id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-354307-9uriite7	Cal, Teresa Segura de la	Unexpected favourable course of Coronavirus Disease 2019 in chronic thromboembolic pulmonary hypertension patients	2020-06-26		.txt	text/plain	1311	90	42	title: Unexpected favourable course of Coronavirus Disease 2019 in chronic thromboembolic pulmonary hypertension patients CPETH patients are usually aged and present with comorbidities 1 in contrast with the usual demographics in the pulmonary arterial hypertension (PAH) population. As CTEPH is consequence of thrombus formation, lifelong anticoagulation is mandatory; while treatments to address increased pulmonary pressures include: pulmonary endarterectomy (PEA), percutaneous balloon pulmonary angioplasty (BPA), and PAH-specific medication 1,2 . Patient 3 was a 46-year-old male with chronic obstructive pulmonary disease and CTEPH diagnosed at the age of 43. We considered four main physiopathological pathways potentially involved in this paradoxical behaviour: 1) reduced viral entrance to the pulmonary endothelium, 2) weakened ability to mount a severe inflammatory response, 2) dysregulation of pulmonary vasoactivity and 4) chronic anticoagulation to offset SARS-CoV-2 induced coagulopathy. A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus-induced lung injury	./cache/cord-354307-9uriite7.txt	./txt/cord-354307-9uriite7.txt