id author title date pages extension mime words sentences flesch summary cache txt cord-355039-qi4fwqbc Azar, William S. COVID-19 and diabetes mellitus: how one pandemic worsens the other 2020-08-02 .txt text/plain 7350 392 44 In this review, we elucidate suggested mechanisms underlying the increased susceptibility of patients with diabetes to infection with SARS-CoV-2 with a more severe COVID-19 disease. The different studies presented suggest that patients with diabetes may not only be prone to a more severe COVID-19 disease, but also to an increased risk of infection with SARS-CoV-2. Although plausible hypotheses for the increased risk of COVID-19 infection in patients with diabetes and other chronic diseases like hypertension are still under investigation, ACE2 seems to play a key role in the association between COVID-19 and DM [60] (Table 1 ). suggested that higher ACE2 expression in the lungs increased susceptibility to SARS-CoV-2 infection with more severe complications and was causally correlated with diabetes [68] . In this review, we describe three potential mechanisms underlying the increased susceptibility of patients with diabetes to a more severe COVID-19 disease, leading to higher morbidity and mortality. ./cache/cord-355039-qi4fwqbc.txt ./txt/cord-355039-qi4fwqbc.txt