id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-355395-rckzi8vz	Tian, Dandan	Hepatic complications of COVID‐19 and its treatment	2020-05-21		.txt	text/plain	2896	137	40	SARS‐CoV‐2 can cause liver injury through systemic inflammatory response syndrome (SIRS), cytokine storms, ischemia‐reperfusion injury, side effects of treatment drugs, and underlying liver disease and can attack liver cells directly via ACE2. Considering limited number of autopsy cases in patients with COVID-19 studied and the relatively low expression of ACE2 in liver, liver damage directly caused by SARS-CoV-2 infection of hepatocytes deserves further investigation. It was speculated that in addition to the virus itself causing liver injury, immune injury, systemic inflammatory response syndrome (SIRS), cytokine storms, ischemia and hypoxia reperfusion injury, and drug-induced injury may be the main mechanisms that cause secondary liver injury in patients with COVID-19 [11] [12] 14, 27 . Patients with COVID-19 have varying degrees of hypoxemia, with more than 40% requiring oxygen therapy 5 Drug hepatotoxicity( Figure 2) In China, the incidence of drug-induced liver injury is second only to viral hepatitis and fatty liver disease (including alcoholic and non-alcoholic).	./cache/cord-355395-rckzi8vz.txt	./txt/cord-355395-rckzi8vz.txt