id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-355830-kctpftm9	Perisetti, Abhilash	Putative Mechanisms of diarrhea in COVID-19	2020-06-12		.txt	text/plain	635	42	58	The presence of viral RNA in stools samples has been noted in up to 53.4% of cases of diarrhea in COVID-19, but it is unclear if the presence of RNA correlates with diarrheal symptoms 1 . If the diarrhea is due to the direct cytopathic effects, then stool viral RNA is expected to be positive in significantly higher numbers in COVID-19 as compared to non-cytopathic causes. However, fecal calprotectin is elevated in COVID-19 patients with persistent diarrhea, which is consistent with increased gut inflammation. The COVID-19 patients are known to have altered gut flora 4 , which could be due to the use of antimicrobials, concomitant infections, and the severe illness itself. The composition of gut flora could also be altered by an increase in proinflammatory mediators because of viral-induced inflammation. It is unclear if the factors mentioned above play a role alone or in combination in causing diarrhea in COVID-19 patients.	./cache/cord-355830-kctpftm9.txt	./txt/cord-355830-kctpftm9.txt