id author title date pages extension mime words sentences flesch summary cache txt cord-266034-811lov8f Benameur, Karima Encephalopathy and Encephalitis Associated with Cerebrospinal Fluid Cytokine Alterations and Coronavirus Disease, Atlanta, Georgia, USA, 2020 2020-09-17 .txt text/plain 2447 123 43 CSF analysis also showed markedly increased levels of interleukin (IL)-6, IL-8, and IL-10, but severe acute respiratory syndrome coronavirus 2 was not identified in any CSF sample. Because MRI changes seen in these patients could be caused by hypercoagulability (15) or metabolic encephalopathy (16) , we propose that CSF investigation can improve the distinction between neurologic involvement of SARS-CoV-2 (or neuro-COVID) and neurologic symptoms caused by other COVID-related causes. The failure to detect CSF SARS-CoV-2 RNA does not diminish the likelihood of direct CNS infection because it is only recovered from blood in 1% of the actively infected cases (18) , and increased levels CSF IgM are also more commonly found as evidence for CNS infection than viral recovery in other encephalitides, including those for infection with Japanese encephalitis virus (19) , dengue virus (20) , human parvovirus 4 (21) , and rabies virus (22) . ./cache/cord-266034-811lov8f.txt ./txt/cord-266034-811lov8f.txt