id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-339886-th1da1bb	Gardy, Jennifer L.	Towards a genomics-informed, real-time, global pathogen surveillance system	2017-11-13		.txt	text/plain	8776	380	35	Given that outbreaks of emerging infectious diseases (EIDs) most often occur in settings with minimal laboratory capacity, where routine culture and bench-top sequencing are simply not feasible, the need for a portable diagnostic platform capable of in situ clinical metagenomics and outbreak surveillance is evident. Portable genome sequencing technology and digital epidemiology platforms form the foundation for both real-time pathogen and disease surveillance systems and outbreak response efforts, all of which exist within the One Health context, in which surveillance, outbreak detection and response span the human, animal and environmental health domains. For example, genome sequences from a raccoon-associated variant of rabies virus (RRV), when paired with fine-scale geographic information and data from Canadian and US wildlife rabies vaccination programmes, demonstrated that multiple cross-border incursions were responsible for the expansion of RRV into Canada and sustained outbreaks in several provinces 70 ; this finding led to renewed concern about and action against rabies on the part of public health authorities 71 .	./cache/cord-339886-th1da1bb.txt	./txt/cord-339886-th1da1bb.txt