id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-001262-8s7g2wvd	Zheng, Guoping	Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study	2014-04-04		.txt	text/plain	4924	286	52	title: Treatment of acute respiratory distress syndrome with allogeneic adipose-derived mesenchymal stem cells: a randomized, placebo-controlled pilot study The objectives of this study were first to examine the possible adverse events after systemic administration of allogeneic adipose-derived MSCs in ARDS patients and second to determine potential efficacy of MSCs on ARDS. METHODS: Twelve adult patients meeting the Berlin definition of acute respiratory distress syndrome with a PaO(2)/FiO(2) ratio of < 200 were randomized to receive allogeneic adipose-derived MSCs or placebo in a 1:1 fashion. Many studies, including publications from our group [11, 12] , have demonstrated compelling evidence of the benefits of MSCs from both bone marrow [13] [14] [15] and adipose tissues [16] [17] [18] in animal models for lung injury and ARDS. In this randomized, placebo-controlled phase I clinical trial, the primary goal was to evaluate the safety and feasibility of systemic administration of allogeneic adipose-derived MSCs in ARDS patients.	./cache/cord-001262-8s7g2wvd.txt	./txt/cord-001262-8s7g2wvd.txt