id author title date pages extension mime words sentences flesch summary cache txt cord-027811-vk3qnumx Freedberg, Daniel E. Impact of Fiber-Based Enteral Nutrition on the Gut Microbiome of ICU Patients Receiving Broad-Spectrum Antibiotics: A Randomized Pilot Trial 2020-06-11 .txt text/plain 3836 201 50 title: Impact of Fiber-Based Enteral Nutrition on the Gut Microbiome of ICU Patients Receiving Broad-Spectrum Antibiotics: A Randomized Pilot Trial CONCLUSIONS: Enteral fiber was associated with nonsignificant trends toward increased relative abundance of short-chain fatty acid–producing bacteria and increased short-chain fatty acid levels among ICU patients receiving broad-spectrum IV antibiotics. This pilot study was designed to test the hypothesis that fiber-based enteral nutrition increases the levels of SCFA-producing bacteria and SCFA levels in ICU patients receiving broad-spectrum IV antibiotics, with a goal of generating effect size estimates that could be used as the basis for future studies involving fiber. A study testing 7 days of 7 g/d inulin versus maltodextrin supplementation in 22 ICU adults initiating enteral nutrition found no difference in fecal abundance of Faecalibacterium prausnitzii or Bifidobacteria, or in fecal SCFA levels (24) . ./cache/cord-027811-vk3qnumx.txt ./txt/cord-027811-vk3qnumx.txt