id author title date pages extension mime words sentences flesch summary cache txt cord-033791-q0wizf2n Kavirayani, Akhila The Lazarus effect of very high-dose intravenous anakinra in severe non-familial CNS-HLH 2020-10-15 .txt text/plain 614 50 29 title: The Lazarus effect of very high-dose intravenous anakinra in severe non-familial CNS-HLH Abbreviations: BAL -bronchoalveolar lavage, CRP -C-reactive protein, TRAPS -Tumour necrosis factor receptor-associated periodic syndrome, WCC -white cell count, FHL -Familial Haemophagocytic lymphohistiocytosis IV methyl prednisolone, 1 dose of IV Immunoglobulin, empiric antibiotics and antivirals-IV aciclovir and IV ceftriaxone, switched to meropenem/teicoplanin upon deterioration (doxycycline/clindamycin/co-amoxiclav also administered subsequently with co-trimoxazole/fluconazole prophylaxis) Inotropes for profound hypotension. Interleukin 1 receptor antagonist to treat cytophagic histiocytic panniculitis with secondary hemophagocytic lymphohistiocytosis Benefit of Anakinra in Treating Pediatric Secondary Hemophagocytic Lymphohistiocytosis Successful treatment of severe paediatric rheumatic disease-associated macrophage activation syndrome with interleukin-1 inhibition following conventional immunosuppressive therapy: case series with 12 patie nts Continuous Intravenous Anakinra Infusion to Calm the Cytokine Storm in Macrophage Activation Syndrome Therapeutic Role of Anakinra, an Interleukin-1 Receptor Antagonist, in the Management of Secondary Hemophagocytic Lymphohistiocytosis/Sepsis/Multiple Organ Dysfunction/Macrophage Activating Syndrome in Critically Ill Children*: Pediatric Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab: Alemtuzumab for Refractory HLH Pediatric CNS-isolated hemophagocytic lymphohistiocytosis ./cache/cord-033791-q0wizf2n.txt ./txt/cord-033791-q0wizf2n.txt