id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-285812-l7dpv6nx	O’TOOLE, D.	Pathogenicity of experimental infection with ‘pneumotropic’ porcine coronavirus	1989-07-31		.txt	text/plain	3072	163	45	Virus localisation and lesions were studied in 14 one-week-old piglets following combined intranasal-oral inoculation with a British isolate of 'pneumotropic' porcine coronavirus (pcv) and were compared with the effects of transmissible gastroenteritis virus (tgev) infection in five piglets. Virus localisation and lesions were studied in 14 oneweek-old piglets following combined intranasal-oral inoculation with a British isolate of 'pneumotropic' porcine coronavirus (pcv) and were compared with the effects of transmissible gastroenteritis virus (TGEV) infection in five piglets. Following sterilisation of cages and isolators, a second batch of 12 piglets (Large White cross Landrace) aged seven days from two litters were inoculated with rev (five) or TGEV (five) or were uninoculated controls (two). Between two and six days after infection, acute changes were characterised by individual bronchiolar cells bulging into the lumen, ..; 00I'm Immunocytochemistry r-ev antigen was identified in the epithelial cytoplasm of small and medium bronchioles in eight of 14 piglets and its distribution was closely correlated with areas of pneumonia.	./cache/cord-285812-l7dpv6nx.txt	./txt/cord-285812-l7dpv6nx.txt