id author title date pages extension mime words sentences flesch summary cache txt cord-304562-5xh4p786 Tanabe, Naoya Dupilumab maintenance therapy in an asthmatic patient with coronavirus disease 2019 pneumonia 2020-11-07 .txt text/plain 667 52 57 Dupilumab is widely used as an important biologic 33 agent to control severe condition of asthma, eosinophilic chronic rhinosinusitis, 34 and atopic dermatitis. In the pandemic of severe acute respiratory 35 syndrome-coronavirus-2 (SARS-CoV-2) and its associated respiratory disease, clinical course is summarized in Figure 1 . On day12, chest 51 computed tomography (CT) showed bilateral peripheral-dominant ground glass 52 opacity (GGO) and consolidation ( Fig. 2A) , and because he had several risk 53 factors for severe COVID-19 including obesity and diabetes, he was transferred 54 to intensive care unit at our hospital and received oxygen therapy via face mask 55 (5-6 L/min). Then, mepolizumab Dupilumab is an essential biologic agent for severe type of asthma, 84 eosinophilic chronic rhinosinusitis, and atopic dermatitis. Type 2 inflammation modulates ACE2 and TMPRSS2 in airway 155 epithelial cells Asthma 166 exacerbation associated with COVID-19 pneumonia ./cache/cord-304562-5xh4p786.txt ./txt/cord-304562-5xh4p786.txt