id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-317347-by8albr9	van Ginkel, Frederik W.	Age-dependent immune responses and immune protection after avian coronavirus vaccination	2015-05-28		.txt	text/plain	5792	288	53	The delayed and/or lower antibody response combined with lower IgG avidity indices coincided with increased tracheal inflammation and depletion of tracheal epithelia cells and goblet cells upon IBV field strain challenge. Therefore, the ability of SPF chickens of different age to induce an IBV-specific antibody response and protect against challenge with an IBV field strain was measured. In order to measure IgG (IgY), IgA and IgM antibody levels in plasma and tears of chicken, an IBV-specific enzyme-linked immunosorbent assay (ELISA) was developed as previously described [20] . These data are consistent with a delay in the IgA plasma response to IBV in birds vaccinated at a younger age and a non-significant decline in mean IgA titers in the 1-day-old group. This would be consistent with a drop of presumably natural maternal IBV-specific IgM antibodies in these SPF chickens in the day 7 control age group.	./cache/cord-317347-by8albr9.txt	./txt/cord-317347-by8albr9.txt