id sid tid token lemma pos cord-006870-f5w6fw6q 1 1 key key JJ cord-006870-f5w6fw6q 2 1 : : : cord-006870-f5w6fw6q 2 2 cord-006870-f5w6fw6q cord-006870-f5w6fw6q NNS cord-006870-f5w6fw6q 2 3 authors author NNS cord-006870-f5w6fw6q 2 4 : : : cord-006870-f5w6fw6q 3 1 nan nan NNP cord-006870-f5w6fw6q 3 2 title title NN cord-006870-f5w6fw6q 3 3 : : : cord-006870-f5w6fw6q 3 4 Abstracts abstract NNS cord-006870-f5w6fw6q 3 5 Presented present VBN cord-006870-f5w6fw6q 3 6 at at IN cord-006870-f5w6fw6q 3 7 the the DT cord-006870-f5w6fw6q 3 8 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3 9 Care Care NNP cord-006870-f5w6fw6q 3 10 Society Society NNP cord-006870-f5w6fw6q 3 11 ( ( -LRB- cord-006870-f5w6fw6q 3 12 NCS NCS NNP cord-006870-f5w6fw6q 3 13 ) ) -RRB- cord-006870-f5w6fw6q 3 14 15th 15th JJ cord-006870-f5w6fw6q 3 15 Annual Annual NNP cord-006870-f5w6fw6q 3 16 Meeting Meeting NNP cord-006870-f5w6fw6q 3 17 date date NN cord-006870-f5w6fw6q 3 18 : : : cord-006870-f5w6fw6q 3 19 2017 2017 CD cord-006870-f5w6fw6q 3 20 - - HYPH cord-006870-f5w6fw6q 3 21 09 09 CD cord-006870-f5w6fw6q 3 22 - - SYM cord-006870-f5w6fw6q 3 23 19 19 CD cord-006870-f5w6fw6q 3 24 journal journal NN cord-006870-f5w6fw6q 3 25 : : : cord-006870-f5w6fw6q 4 1 Neurocrit Neurocrit NNP cord-006870-f5w6fw6q 4 2 Care Care NNP cord-006870-f5w6fw6q 4 3 DOI DOI NNP cord-006870-f5w6fw6q 4 4 : : : cord-006870-f5w6fw6q 4 5 10.1007 10.1007 CD cord-006870-f5w6fw6q 4 6 / / SYM cord-006870-f5w6fw6q 4 7 s12028 s12028 CD cord-006870-f5w6fw6q 4 8 - - HYPH cord-006870-f5w6fw6q 4 9 017 017 CD cord-006870-f5w6fw6q 4 10 - - HYPH cord-006870-f5w6fw6q 4 11 0465 0465 CD cord-006870-f5w6fw6q 4 12 - - SYM cord-006870-f5w6fw6q 4 13 9 9 CD cord-006870-f5w6fw6q 4 14 sha sha NN cord-006870-f5w6fw6q 4 15 : : : cord-006870-f5w6fw6q 5 1 5e2b113bc6fbdd6c4bde7905e6e515f30b9078e1 5e2b113bc6fbdd6c4bde7905e6e515f30b9078e1 CD cord-006870-f5w6fw6q 5 2 doc_id doc_id CD cord-006870-f5w6fw6q 5 3 : : : cord-006870-f5w6fw6q 6 1 6870 6870 CD cord-006870-f5w6fw6q 6 2 cord_uid cord_uid NNS cord-006870-f5w6fw6q 6 3 : : : cord-006870-f5w6fw6q 6 4 f5w6fw6q f5w6fw6q NNP cord-006870-f5w6fw6q 6 5 nan nan NNP cord-006870-f5w6fw6q 6 6 External External NNP cord-006870-f5w6fw6q 6 7 ventricular ventricular JJ cord-006870-f5w6fw6q 6 8 drain drain NN cord-006870-f5w6fw6q 6 9 ( ( -LRB- cord-006870-f5w6fw6q 6 10 EVD EVD NNP cord-006870-f5w6fw6q 6 11 ) ) -RRB- cord-006870-f5w6fw6q 6 12 management management NN cord-006870-f5w6fw6q 6 13 after after IN cord-006870-f5w6fw6q 6 14 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6 16 ( ( -LRB- cord-006870-f5w6fw6q 6 17 SAH SAH NNP cord-006870-f5w6fw6q 6 18 ) ) -RRB- cord-006870-f5w6fw6q 6 19 is be VBZ cord-006870-f5w6fw6q 6 20 thought think VBN cord-006870-f5w6fw6q 6 21 to to TO cord-006870-f5w6fw6q 6 22 influence influence VB cord-006870-f5w6fw6q 6 23 patient patient JJ cord-006870-f5w6fw6q 6 24 outcomes outcome NNS cord-006870-f5w6fw6q 6 25 and and CC cord-006870-f5w6fw6q 6 26 complications complication NNS cord-006870-f5w6fw6q 6 27 . . . cord-006870-f5w6fw6q 7 1 Evidence evidence NN cord-006870-f5w6fw6q 7 2 from from IN cord-006870-f5w6fw6q 7 3 single single JJ cord-006870-f5w6fw6q 7 4 center center NN cord-006870-f5w6fw6q 7 5 randomized randomize VBN cord-006870-f5w6fw6q 7 6 controlled control VBN cord-006870-f5w6fw6q 7 7 trials trial NNS cord-006870-f5w6fw6q 7 8 suggest suggest VBP cord-006870-f5w6fw6q 7 9 that that IN cord-006870-f5w6fw6q 7 10 an an DT cord-006870-f5w6fw6q 7 11 early early JJ cord-006870-f5w6fw6q 7 12 clamp clamp NN cord-006870-f5w6fw6q 7 13 trial trial NN cord-006870-f5w6fw6q 7 14 is be VBZ cord-006870-f5w6fw6q 7 15 safe safe JJ cord-006870-f5w6fw6q 7 16 and and CC cord-006870-f5w6fw6q 7 17 associated associate VBN cord-006870-f5w6fw6q 7 18 with with IN cord-006870-f5w6fw6q 7 19 shorter short JJR cord-006870-f5w6fw6q 7 20 ICU ICU NNP cord-006870-f5w6fw6q 7 21 stay stay NN cord-006870-f5w6fw6q 7 22 and and CC cord-006870-f5w6fw6q 7 23 fewer few JJR cord-006870-f5w6fw6q 7 24 EVD EVD NNP cord-006870-f5w6fw6q 7 25 complications complication NNS cord-006870-f5w6fw6q 7 26 . . . cord-006870-f5w6fw6q 8 1 However however RB cord-006870-f5w6fw6q 8 2 , , , cord-006870-f5w6fw6q 8 3 a a DT cord-006870-f5w6fw6q 8 4 recent recent JJ cord-006870-f5w6fw6q 8 5 survey survey NN cord-006870-f5w6fw6q 8 6 revealed reveal VBD cord-006870-f5w6fw6q 8 7 that that IN cord-006870-f5w6fw6q 8 8 most most JJS cord-006870-f5w6fw6q 8 9 neuro neuro NNP cord-006870-f5w6fw6q 8 10 ICU ICU NNP cord-006870-f5w6fw6q 8 11 's be VBZ cord-006870-f5w6fw6q 8 12 across across IN cord-006870-f5w6fw6q 8 13 the the DT cord-006870-f5w6fw6q 8 14 US US NNP cord-006870-f5w6fw6q 8 15 still still RB cord-006870-f5w6fw6q 8 16 adopt adopt VB cord-006870-f5w6fw6q 8 17 a a DT cord-006870-f5w6fw6q 8 18 gradual gradual JJ cord-006870-f5w6fw6q 8 19 wean wean NN cord-006870-f5w6fw6q 8 20 and and CC cord-006870-f5w6fw6q 8 21 continuously continuously RB cord-006870-f5w6fw6q 8 22 draining drain VBG cord-006870-f5w6fw6q 8 23 EVD EVD NNP cord-006870-f5w6fw6q 8 24 strategy strategy NN cord-006870-f5w6fw6q 8 25 . . . cord-006870-f5w6fw6q 9 1 Therefore therefore RB cord-006870-f5w6fw6q 9 2 , , , cord-006870-f5w6fw6q 9 3 we -PRON- PRP cord-006870-f5w6fw6q 9 4 sought seek VBD cord-006870-f5w6fw6q 9 5 to to TO cord-006870-f5w6fw6q 9 6 determine determine VB cord-006870-f5w6fw6q 9 7 the the DT cord-006870-f5w6fw6q 9 8 optimal optimal JJ cord-006870-f5w6fw6q 9 9 approach approach NN cord-006870-f5w6fw6q 9 10 at at IN cord-006870-f5w6fw6q 9 11 our -PRON- PRP$ cord-006870-f5w6fw6q 9 12 institution institution NN cord-006870-f5w6fw6q 9 13 . . . cord-006870-f5w6fw6q 10 1 We -PRON- PRP cord-006870-f5w6fw6q 10 2 reviewed review VBD cord-006870-f5w6fw6q 10 3 200 200 CD cord-006870-f5w6fw6q 10 4 consecutive consecutive JJ cord-006870-f5w6fw6q 10 5 patients patient NNS cord-006870-f5w6fw6q 10 6 admitted admit VBN cord-006870-f5w6fw6q 10 7 to to IN cord-006870-f5w6fw6q 10 8 our -PRON- PRP$ cord-006870-f5w6fw6q 10 9 institution institution NN cord-006870-f5w6fw6q 10 10 from from IN cord-006870-f5w6fw6q 10 11 2012 2012 CD cord-006870-f5w6fw6q 10 12 to to IN cord-006870-f5w6fw6q 10 13 2017 2017 CD cord-006870-f5w6fw6q 10 14 with with IN cord-006870-f5w6fw6q 10 15 nontraumatic nontraumatic JJ cord-006870-f5w6fw6q 10 16 SAH SAH NNP cord-006870-f5w6fw6q 10 17 requiring require VBG cord-006870-f5w6fw6q 10 18 an an DT cord-006870-f5w6fw6q 10 19 EVD EVD NNP cord-006870-f5w6fw6q 10 20 . . . cord-006870-f5w6fw6q 11 1 In in IN cord-006870-f5w6fw6q 11 2 2015 2015 CD cord-006870-f5w6fw6q 11 3 , , , cord-006870-f5w6fw6q 11 4 our -PRON- PRP$ cord-006870-f5w6fw6q 11 5 neurocritical neurocritical NNP cord-006870-f5w6fw6q 11 6 care care NN cord-006870-f5w6fw6q 11 7 unit unit NN cord-006870-f5w6fw6q 11 8 revised revise VBD cord-006870-f5w6fw6q 11 9 our -PRON- PRP$ cord-006870-f5w6fw6q 11 10 internal internal JJ cord-006870-f5w6fw6q 11 11 EVD EVD NNP cord-006870-f5w6fw6q 11 12 management management NN cord-006870-f5w6fw6q 11 13 guideline guideline NN cord-006870-f5w6fw6q 11 14 from from IN cord-006870-f5w6fw6q 11 15 a a DT cord-006870-f5w6fw6q 11 16 gradual gradual JJ cord-006870-f5w6fw6q 11 17 wean wean NN cord-006870-f5w6fw6q 11 18 to to IN cord-006870-f5w6fw6q 11 19 an an DT cord-006870-f5w6fw6q 11 20 early early JJ cord-006870-f5w6fw6q 11 21 clamp clamp NN cord-006870-f5w6fw6q 11 22 trial trial NN cord-006870-f5w6fw6q 11 23 approach approach NN cord-006870-f5w6fw6q 11 24 . . . cord-006870-f5w6fw6q 12 1 We -PRON- PRP cord-006870-f5w6fw6q 12 2 performed perform VBD cord-006870-f5w6fw6q 12 3 a a DT cord-006870-f5w6fw6q 12 4 retrospective retrospective JJ cord-006870-f5w6fw6q 12 5 multivariate multivariate JJ cord-006870-f5w6fw6q 12 6 analysis analysis NN cord-006870-f5w6fw6q 12 7 to to TO cord-006870-f5w6fw6q 12 8 compare compare VB cord-006870-f5w6fw6q 12 9 outcomes outcome NNS cord-006870-f5w6fw6q 12 10 before before IN cord-006870-f5w6fw6q 12 11 and and CC cord-006870-f5w6fw6q 12 12 after after IN cord-006870-f5w6fw6q 12 13 our -PRON- PRP$ cord-006870-f5w6fw6q 12 14 guideline guideline NN cord-006870-f5w6fw6q 12 15 change change NN cord-006870-f5w6fw6q 12 16 . . . cord-006870-f5w6fw6q 13 1 Patients patient NNS cord-006870-f5w6fw6q 13 2 that that WDT cord-006870-f5w6fw6q 13 3 were be VBD cord-006870-f5w6fw6q 13 4 gradually gradually RB cord-006870-f5w6fw6q 13 5 weaned wean VBN cord-006870-f5w6fw6q 13 6 after after IN cord-006870-f5w6fw6q 13 7 institution institution NN cord-006870-f5w6fw6q 13 8 of of IN cord-006870-f5w6fw6q 13 9 the the DT cord-006870-f5w6fw6q 13 10 new new JJ cord-006870-f5w6fw6q 13 11 guideline guideline NN cord-006870-f5w6fw6q 13 12 were be VBD cord-006870-f5w6fw6q 13 13 also also RB cord-006870-f5w6fw6q 13 14 included include VBN cord-006870-f5w6fw6q 13 15 in in IN cord-006870-f5w6fw6q 13 16 the the DT cord-006870-f5w6fw6q 13 17 early early JJ cord-006870-f5w6fw6q 13 18 clamp clamp NN cord-006870-f5w6fw6q 13 19 trial trial NN cord-006870-f5w6fw6q 13 20 group group NN cord-006870-f5w6fw6q 13 21 . . . cord-006870-f5w6fw6q 14 1 We -PRON- PRP cord-006870-f5w6fw6q 14 2 observed observe VBD cord-006870-f5w6fw6q 14 3 a a DT cord-006870-f5w6fw6q 14 4 significant significant JJ cord-006870-f5w6fw6q 14 5 reduction reduction NN cord-006870-f5w6fw6q 14 6 in in IN cord-006870-f5w6fw6q 14 7 ventriculoperitoneal ventriculoperitoneal NN cord-006870-f5w6fw6q 14 8 shunt shunt NN cord-006870-f5w6fw6q 14 9 ( ( -LRB- cord-006870-f5w6fw6q 14 10 VPS VPS NNP cord-006870-f5w6fw6q 14 11 ) ) -RRB- cord-006870-f5w6fw6q 14 12 rates rate NNS cord-006870-f5w6fw6q 14 13 after after IN cord-006870-f5w6fw6q 14 14 changing change VBG cord-006870-f5w6fw6q 14 15 to to IN cord-006870-f5w6fw6q 14 16 an an DT cord-006870-f5w6fw6q 14 17 early early JJ cord-006870-f5w6fw6q 14 18 clamp clamp NN cord-006870-f5w6fw6q 14 19 trial trial NN cord-006870-f5w6fw6q 14 20 approach approach NN cord-006870-f5w6fw6q 14 21 ( ( -LRB- cord-006870-f5w6fw6q 14 22 13 13 CD cord-006870-f5w6fw6q 14 23 % % NN cord-006870-f5w6fw6q 14 24 early early JJ cord-006870-f5w6fw6q 14 25 clamp clamp NN cord-006870-f5w6fw6q 14 26 vs vs IN cord-006870-f5w6fw6q 14 27 35 35 CD cord-006870-f5w6fw6q 14 28 % % NN cord-006870-f5w6fw6q 14 29 gradual gradual JJ cord-006870-f5w6fw6q 14 30 wean wean NN cord-006870-f5w6fw6q 14 31 , , , cord-006870-f5w6fw6q 14 32 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 14 33 , , , cord-006870-f5w6fw6q 14 34 OR=0.208 OR=0.208 VBN cord-006870-f5w6fw6q 14 35 on on IN cord-006870-f5w6fw6q 14 36 multivariateanalysis multivariateanalysis NN cord-006870-f5w6fw6q 14 37 ) ) -RRB- cord-006870-f5w6fw6q 14 38 . . . cord-006870-f5w6fw6q 15 1 There there EX cord-006870-f5w6fw6q 15 2 was be VBD cord-006870-f5w6fw6q 15 3 no no DT cord-006870-f5w6fw6q 15 4 increase increase NN cord-006870-f5w6fw6q 15 5 in in IN cord-006870-f5w6fw6q 15 6 delayed delay VBN cord-006870-f5w6fw6q 15 7 VPS VPS NNP cord-006870-f5w6fw6q 15 8 placement placement NN cord-006870-f5w6fw6q 15 9 at at IN cord-006870-f5w6fw6q 15 10 3 3 CD cord-006870-f5w6fw6q 15 11 months month NNS cord-006870-f5w6fw6q 15 12 ( ( -LRB- cord-006870-f5w6fw6q 15 13 8.6 8.6 CD cord-006870-f5w6fw6q 15 14 % % NN cord-006870-f5w6fw6q 15 15 vs vs IN cord-006870-f5w6fw6q 15 16 9.3 9.3 CD cord-006870-f5w6fw6q 15 17 % % NN cord-006870-f5w6fw6q 15 18 , , , cord-006870-f5w6fw6q 15 19 p=0.41 p=0.41 NNP cord-006870-f5w6fw6q 15 20 ) ) -RRB- cord-006870-f5w6fw6q 15 21 . . . cord-006870-f5w6fw6q 16 1 An an DT cord-006870-f5w6fw6q 16 2 early early JJ cord-006870-f5w6fw6q 16 3 clamp clamp NN cord-006870-f5w6fw6q 16 4 trial trial NN cord-006870-f5w6fw6q 16 5 approach approach NN cord-006870-f5w6fw6q 16 6 was be VBD cord-006870-f5w6fw6q 16 7 also also RB cord-006870-f5w6fw6q 16 8 associated associate VBN cord-006870-f5w6fw6q 16 9 with with IN cord-006870-f5w6fw6q 16 10 a a DT cord-006870-f5w6fw6q 16 11 shorter short JJR cord-006870-f5w6fw6q 16 12 mean mean JJ cord-006870-f5w6fw6q 16 13 EVD EVD NNP cord-006870-f5w6fw6q 16 14 duration duration NN cord-006870-f5w6fw6q 16 15 ( ( -LRB- cord-006870-f5w6fw6q 16 16 10.2 10.2 CD cord-006870-f5w6fw6q 16 17 vs vs IN cord-006870-f5w6fw6q 16 18 15.6 15.6 CD cord-006870-f5w6fw6q 16 19 days day NNS cord-006870-f5w6fw6q 16 20 , , , cord-006870-f5w6fw6q 16 21 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 16 22 ) ) -RRB- cord-006870-f5w6fw6q 16 23 , , , cord-006870-f5w6fw6q 16 24 shorter short JJR cord-006870-f5w6fw6q 16 25 ICU ICU NNP cord-006870-f5w6fw6q 16 26 length length NN cord-006870-f5w6fw6q 16 27 of of IN cord-006870-f5w6fw6q 16 28 stay stay NN cord-006870-f5w6fw6q 16 29 ( ( -LRB- cord-006870-f5w6fw6q 16 30 14.2 14.2 CD cord-006870-f5w6fw6q 16 31 vs vs IN cord-006870-f5w6fw6q 16 32 16.9 16.9 CD cord-006870-f5w6fw6q 16 33 days day NNS cord-006870-f5w6fw6q 16 34 , , , cord-006870-f5w6fw6q 16 35 p=0.001 p=0.001 NNP cord-006870-f5w6fw6q 16 36 ) ) -RRB- cord-006870-f5w6fw6q 16 37 , , , cord-006870-f5w6fw6q 16 38 shorter short JJR cord-006870-f5w6fw6q 16 39 hospital hospital NN cord-006870-f5w6fw6q 16 40 length length NN cord-006870-f5w6fw6q 16 41 of of IN cord-006870-f5w6fw6q 16 42 stay stay NN cord-006870-f5w6fw6q 16 43 ( ( -LRB- cord-006870-f5w6fw6q 16 44 18.2 18.2 CD cord-006870-f5w6fw6q 16 45 vs vs IN cord-006870-f5w6fw6q 16 46 23.7 23.7 CD cord-006870-f5w6fw6q 16 47 days day NNS cord-006870-f5w6fw6q 16 48 , , , cord-006870-f5w6fw6q 16 49 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 16 50 ) ) -RRB- cord-006870-f5w6fw6q 16 51 , , , cord-006870-f5w6fw6q 16 52 lower low JJR cord-006870-f5w6fw6q 16 53 rates rate NNS cord-006870-f5w6fw6q 16 54 of of IN cord-006870-f5w6fw6q 16 55 non non JJ cord-006870-f5w6fw6q 16 56 - - JJ cord-006870-f5w6fw6q 16 57 functioning functioning JJ cord-006870-f5w6fw6q 16 58 EVD EVD NNP cord-006870-f5w6fw6q 16 59 ( ( -LRB- cord-006870-f5w6fw6q 16 60 15 15 CD cord-006870-f5w6fw6q 16 61 % % NN cord-006870-f5w6fw6q 16 62 vs vs IN cord-006870-f5w6fw6q 16 63 30 30 CD cord-006870-f5w6fw6q 16 64 % % NN cord-006870-f5w6fw6q 16 65 , , , cord-006870-f5w6fw6q 16 66 p=0.025 p=0.025 NNP cord-006870-f5w6fw6q 16 67 ) ) -RRB- cord-006870-f5w6fw6q 16 68 , , , cord-006870-f5w6fw6q 16 69 and and CC cord-006870-f5w6fw6q 16 70 fewer few JJR cord-006870-f5w6fw6q 16 71 ventriculostomyassociated ventriculostomyassociate VBN cord-006870-f5w6fw6q 16 72 infections infection NNS cord-006870-f5w6fw6q 16 73 ( ( -LRB- cord-006870-f5w6fw6q 16 74 1.3 1.3 CD cord-006870-f5w6fw6q 16 75 % % NN cord-006870-f5w6fw6q 16 76 vs vs IN cord-006870-f5w6fw6q 16 77 8.8 8.8 CD cord-006870-f5w6fw6q 16 78 % % NN cord-006870-f5w6fw6q 16 79 , , , cord-006870-f5w6fw6q 16 80 p=0.039 p=0.039 NNP cord-006870-f5w6fw6q 16 81 ) ) -RRB- cord-006870-f5w6fw6q 16 82 . . . cord-006870-f5w6fw6q 17 1 We -PRON- PRP cord-006870-f5w6fw6q 17 2 found find VBD cord-006870-f5w6fw6q 17 3 no no DT cord-006870-f5w6fw6q 17 4 difference difference NN cord-006870-f5w6fw6q 17 5 in in IN cord-006870-f5w6fw6q 17 6 symptomatic symptomatic JJ cord-006870-f5w6fw6q 17 7 vasospasm vasospasm NN cord-006870-f5w6fw6q 17 8 rates rate NNS cord-006870-f5w6fw6q 17 9 between between IN cord-006870-f5w6fw6q 17 10 the the DT cord-006870-f5w6fw6q 17 11 groups group NNS cord-006870-f5w6fw6q 17 12 ( ( -LRB- cord-006870-f5w6fw6q 17 13 20.2 20.2 CD cord-006870-f5w6fw6q 17 14 % % NN cord-006870-f5w6fw6q 17 15 vs vs IN cord-006870-f5w6fw6q 17 16 24.6 24.6 CD cord-006870-f5w6fw6q 17 17 % % NN cord-006870-f5w6fw6q 17 18 , , , cord-006870-f5w6fw6q 17 19 p=0.52 p=0.52 NNP cord-006870-f5w6fw6q 17 20 ) ) -RRB- cord-006870-f5w6fw6q 17 21 . . . cord-006870-f5w6fw6q 18 1 An an DT cord-006870-f5w6fw6q 18 2 early early JJ cord-006870-f5w6fw6q 18 3 clamp clamp NN cord-006870-f5w6fw6q 18 4 trial trial NN cord-006870-f5w6fw6q 18 5 approach approach NN cord-006870-f5w6fw6q 18 6 is be VBZ cord-006870-f5w6fw6q 18 7 associated associate VBN cord-006870-f5w6fw6q 18 8 with with IN cord-006870-f5w6fw6q 18 9 fewer few JJR cord-006870-f5w6fw6q 18 10 complications complication NNS cord-006870-f5w6fw6q 18 11 and and CC cord-006870-f5w6fw6q 18 12 shorter short JJR cord-006870-f5w6fw6q 18 13 length length NN cord-006870-f5w6fw6q 18 14 of of IN cord-006870-f5w6fw6q 18 15 stay stay NN cord-006870-f5w6fw6q 18 16 compared compare VBN cord-006870-f5w6fw6q 18 17 to to IN cord-006870-f5w6fw6q 18 18 a a DT cord-006870-f5w6fw6q 18 19 gradual gradual JJ cord-006870-f5w6fw6q 18 20 EVD EVD NNP cord-006870-f5w6fw6q 18 21 wean wean NN cord-006870-f5w6fw6q 18 22 . . . cord-006870-f5w6fw6q 19 1 Prospective prospective JJ cord-006870-f5w6fw6q 19 2 multicenter multicenter JJ cord-006870-f5w6fw6q 19 3 studies study NNS cord-006870-f5w6fw6q 19 4 are be VBP cord-006870-f5w6fw6q 19 5 needed need VBN cord-006870-f5w6fw6q 19 6 to to TO cord-006870-f5w6fw6q 19 7 provide provide VB cord-006870-f5w6fw6q 19 8 further further JJ cord-006870-f5w6fw6q 19 9 insight insight NN cord-006870-f5w6fw6q 19 10 into into IN cord-006870-f5w6fw6q 19 11 the the DT cord-006870-f5w6fw6q 19 12 best good JJS cord-006870-f5w6fw6q 19 13 strategy strategy NN cord-006870-f5w6fw6q 19 14 . . . cord-006870-f5w6fw6q 20 1 Autoimmune Autoimmune NNP cord-006870-f5w6fw6q 20 2 encephalitis encephalitis RB cord-006870-f5w6fw6q 20 3 refers refer VBZ cord-006870-f5w6fw6q 20 4 to to IN cord-006870-f5w6fw6q 20 5 rare rare JJ cord-006870-f5w6fw6q 20 6 sometimes sometimes RB cord-006870-f5w6fw6q 20 7 paraneoplastic paraneoplastic JJ cord-006870-f5w6fw6q 20 8 conditions condition NNS cord-006870-f5w6fw6q 20 9 in in IN cord-006870-f5w6fw6q 20 10 which which WDT cord-006870-f5w6fw6q 20 11 the the DT cord-006870-f5w6fw6q 20 12 immune immune JJ cord-006870-f5w6fw6q 20 13 system system NN cord-006870-f5w6fw6q 20 14 attacks attack VBZ cord-006870-f5w6fw6q 20 15 the the DT cord-006870-f5w6fw6q 20 16 brain brain NN cord-006870-f5w6fw6q 20 17 , , , cord-006870-f5w6fw6q 20 18 leading lead VBG cord-006870-f5w6fw6q 20 19 to to IN cord-006870-f5w6fw6q 20 20 altered altered JJ cord-006870-f5w6fw6q 20 21 function function NN cord-006870-f5w6fw6q 20 22 . . . cord-006870-f5w6fw6q 21 1 Delayed delay VBN cord-006870-f5w6fw6q 21 2 diagnosis diagnosis NN cord-006870-f5w6fw6q 21 3 and and CC cord-006870-f5w6fw6q 21 4 treatment treatment NN cord-006870-f5w6fw6q 21 5 potentially potentially RB cord-006870-f5w6fw6q 21 6 leads lead VBZ cord-006870-f5w6fw6q 21 7 to to IN cord-006870-f5w6fw6q 21 8 permanent permanent JJ cord-006870-f5w6fw6q 21 9 neurological neurological JJ cord-006870-f5w6fw6q 21 10 injury injury NN cord-006870-f5w6fw6q 21 11 or or CC cord-006870-f5w6fw6q 21 12 death death NN cord-006870-f5w6fw6q 21 13 . . . cord-006870-f5w6fw6q 22 1 The the DT cord-006870-f5w6fw6q 22 2 primary primary JJ cord-006870-f5w6fw6q 22 3 objective objective NN cord-006870-f5w6fw6q 22 4 of of IN cord-006870-f5w6fw6q 22 5 this this DT cord-006870-f5w6fw6q 22 6 study study NN cord-006870-f5w6fw6q 22 7 was be VBD cord-006870-f5w6fw6q 22 8 to to TO cord-006870-f5w6fw6q 22 9 analyze analyze VB cord-006870-f5w6fw6q 22 10 the the DT cord-006870-f5w6fw6q 22 11 admission admission NN cord-006870-f5w6fw6q 22 12 and and CC cord-006870-f5w6fw6q 22 13 discharge discharge NN cord-006870-f5w6fw6q 22 14 modified modify VBN cord-006870-f5w6fw6q 22 15 Rankin Rankin NNP cord-006870-f5w6fw6q 22 16 Scale Scale NNP cord-006870-f5w6fw6q 22 17 ( ( -LRB- cord-006870-f5w6fw6q 22 18 mRS mRS : cord-006870-f5w6fw6q 22 19 ) ) -RRB- cord-006870-f5w6fw6q 22 20 assessments assessment NNS cord-006870-f5w6fw6q 22 21 among among IN cord-006870-f5w6fw6q 22 22 patients patient NNS cord-006870-f5w6fw6q 22 23 diagnosed diagnose VBN cord-006870-f5w6fw6q 22 24 with with IN cord-006870-f5w6fw6q 22 25 autoimmune autoimmune JJ cord-006870-f5w6fw6q 22 26 encephalitis encephalitis RB cord-006870-f5w6fw6q 22 27 , , , cord-006870-f5w6fw6q 22 28 and and CC cord-006870-f5w6fw6q 22 29 to to TO cord-006870-f5w6fw6q 22 30 identify identify VB cord-006870-f5w6fw6q 22 31 any any DT cord-006870-f5w6fw6q 22 32 effectiveness effectiveness NN cord-006870-f5w6fw6q 22 33 of of IN cord-006870-f5w6fw6q 22 34 immunosuppressive immunosuppressive JJ cord-006870-f5w6fw6q 22 35 therapy therapy NN cord-006870-f5w6fw6q 22 36 on on IN cord-006870-f5w6fw6q 22 37 a a DT cord-006870-f5w6fw6q 22 38 subset subset NN cord-006870-f5w6fw6q 22 39 of of IN cord-006870-f5w6fw6q 22 40 these these DT cord-006870-f5w6fw6q 22 41 patients patient NNS cord-006870-f5w6fw6q 22 42 . . . cord-006870-f5w6fw6q 23 1 Through through IN cord-006870-f5w6fw6q 23 2 retrospective retrospective JJ cord-006870-f5w6fw6q 23 3 chart chart NN cord-006870-f5w6fw6q 23 4 review review NN cord-006870-f5w6fw6q 23 5 we -PRON- PRP cord-006870-f5w6fw6q 23 6 identified identify VBD cord-006870-f5w6fw6q 23 7 patients patient NNS cord-006870-f5w6fw6q 23 8 that that WDT cord-006870-f5w6fw6q 23 9 met meet VBD cord-006870-f5w6fw6q 23 10 currently currently RB cord-006870-f5w6fw6q 23 11 accepted accept VBN cord-006870-f5w6fw6q 23 12 clinical clinical JJ cord-006870-f5w6fw6q 23 13 and and CC cord-006870-f5w6fw6q 23 14 serological serological JJ cord-006870-f5w6fw6q 23 15 criterion criterion NN cord-006870-f5w6fw6q 23 16 for for IN cord-006870-f5w6fw6q 23 17 autoimmune autoimmune JJ cord-006870-f5w6fw6q 23 18 encephalitis encephalitis RB cord-006870-f5w6fw6q 23 19 . . . cord-006870-f5w6fw6q 24 1 Clinical clinical JJ cord-006870-f5w6fw6q 24 2 data datum NNS cord-006870-f5w6fw6q 24 3 was be VBD cord-006870-f5w6fw6q 24 4 obtained obtain VBN cord-006870-f5w6fw6q 24 5 on on IN cord-006870-f5w6fw6q 24 6 these these DT cord-006870-f5w6fw6q 24 7 cases case NNS cord-006870-f5w6fw6q 24 8 and and CC cord-006870-f5w6fw6q 24 9 a a DT cord-006870-f5w6fw6q 24 10 modified modify VBN cord-006870-f5w6fw6q 24 11 Rankin Rankin NNP cord-006870-f5w6fw6q 24 12 Score Score NNP cord-006870-f5w6fw6q 24 13 mRS mRS : cord-006870-f5w6fw6q 24 14 was be VBD cord-006870-f5w6fw6q 24 15 assessed assess VBN cord-006870-f5w6fw6q 24 16 on on IN cord-006870-f5w6fw6q 24 17 both both DT cord-006870-f5w6fw6q 24 18 hospital hospital NN cord-006870-f5w6fw6q 24 19 admission admission NN cord-006870-f5w6fw6q 24 20 and and CC cord-006870-f5w6fw6q 24 21 discharge discharge NN cord-006870-f5w6fw6q 24 22 or or CC cord-006870-f5w6fw6q 24 23 subsequent subsequent JJ cord-006870-f5w6fw6q 24 24 ' ' `` cord-006870-f5w6fw6q 24 25 best good JJS cord-006870-f5w6fw6q 24 26 clinical clinical JJ cord-006870-f5w6fw6q 24 27 ' ' '' cord-006870-f5w6fw6q 24 28 visit visit NN cord-006870-f5w6fw6q 24 29 . . . cord-006870-f5w6fw6q 25 1 Assessment assessment NN cord-006870-f5w6fw6q 25 2 of of IN cord-006870-f5w6fw6q 25 3 " " `` cord-006870-f5w6fw6q 25 4 improvement improvement NN cord-006870-f5w6fw6q 25 5 " " '' cord-006870-f5w6fw6q 25 6 from from IN cord-006870-f5w6fw6q 25 7 initial initial JJ cord-006870-f5w6fw6q 25 8 therapy therapy NN cord-006870-f5w6fw6q 25 9 was be VBD cord-006870-f5w6fw6q 25 10 based base VBN cord-006870-f5w6fw6q 25 11 on on IN cord-006870-f5w6fw6q 25 12 any any DT cord-006870-f5w6fw6q 25 13 decrease decrease NN cord-006870-f5w6fw6q 25 14 in in IN cord-006870-f5w6fw6q 25 15 mRS mrs PRP$ cord-006870-f5w6fw6q 25 16 score score NN cord-006870-f5w6fw6q 25 17 and and CC cord-006870-f5w6fw6q 25 18 clinical clinical JJ cord-006870-f5w6fw6q 25 19 neurological neurological JJ cord-006870-f5w6fw6q 25 20 functional functional JJ cord-006870-f5w6fw6q 25 21 improvement improvement NN cord-006870-f5w6fw6q 25 22 in in IN cord-006870-f5w6fw6q 25 23 accordance accordance NN cord-006870-f5w6fw6q 25 24 with with IN cord-006870-f5w6fw6q 25 25 physician physician NN cord-006870-f5w6fw6q 25 26 and and CC cord-006870-f5w6fw6q 25 27 patient patient JJ cord-006870-f5w6fw6q 25 28 affirmation affirmation NN cord-006870-f5w6fw6q 25 29 by by IN cord-006870-f5w6fw6q 25 30 the the DT cord-006870-f5w6fw6q 25 31 time time NN cord-006870-f5w6fw6q 25 32 of of IN cord-006870-f5w6fw6q 25 33 discharge discharge NN cord-006870-f5w6fw6q 25 34 . . . cord-006870-f5w6fw6q 26 1 Seventy seventy CD cord-006870-f5w6fw6q 26 2 - - HYPH cord-006870-f5w6fw6q 26 3 seven seven CD cord-006870-f5w6fw6q 26 4 patients patient NNS cord-006870-f5w6fw6q 26 5 met meet VBD cord-006870-f5w6fw6q 26 6 criterion criterion NN cord-006870-f5w6fw6q 26 7 for for IN cord-006870-f5w6fw6q 26 8 clinical clinical JJ cord-006870-f5w6fw6q 26 9 or or CC cord-006870-f5w6fw6q 26 10 serological serological JJ cord-006870-f5w6fw6q 26 11 autoimmune autoimmune JJ cord-006870-f5w6fw6q 26 12 encephalitis encephalitis RB cord-006870-f5w6fw6q 26 13 . . . cord-006870-f5w6fw6q 27 1 Of of IN cord-006870-f5w6fw6q 27 2 these these DT cord-006870-f5w6fw6q 27 3 patients patient NNS cord-006870-f5w6fw6q 27 4 , , , cord-006870-f5w6fw6q 27 5 11 11 CD cord-006870-f5w6fw6q 27 6 had have VBD cord-006870-f5w6fw6q 27 7 cancer cancer NN cord-006870-f5w6fw6q 27 8 and and CC cord-006870-f5w6fw6q 27 9 66 66 CD cord-006870-f5w6fw6q 27 10 did do VBD cord-006870-f5w6fw6q 27 11 not not RB cord-006870-f5w6fw6q 27 12 have have VB cord-006870-f5w6fw6q 27 13 known know VBN cord-006870-f5w6fw6q 27 14 cancer cancer NN cord-006870-f5w6fw6q 27 15 . . . cord-006870-f5w6fw6q 28 1 Fifty fifty CD cord-006870-f5w6fw6q 28 2 - - HYPH cord-006870-f5w6fw6q 28 3 seven seven CD cord-006870-f5w6fw6q 28 4 ( ( -LRB- cord-006870-f5w6fw6q 28 5 74 74 CD cord-006870-f5w6fw6q 28 6 % % NN cord-006870-f5w6fw6q 28 7 ) ) -RRB- cord-006870-f5w6fw6q 28 8 patients patient NNS cord-006870-f5w6fw6q 28 9 underwent undergo VBD cord-006870-f5w6fw6q 28 10 immunosuppressive immunosuppressive JJ cord-006870-f5w6fw6q 28 11 therapy therapy NN cord-006870-f5w6fw6q 28 12 with with IN cord-006870-f5w6fw6q 28 13 corticosteroids corticosteroid NNS cord-006870-f5w6fw6q 28 14 , , , cord-006870-f5w6fw6q 28 15 IVIg IVIg NNP cord-006870-f5w6fw6q 28 16 , , , cord-006870-f5w6fw6q 28 17 and/or and/or CC cord-006870-f5w6fw6q 28 18 plasma plasma NN cord-006870-f5w6fw6q 28 19 exchange exchange NN cord-006870-f5w6fw6q 28 20 and and CC cord-006870-f5w6fw6q 28 21 30 30 CD cord-006870-f5w6fw6q 28 22 patients patient NNS cord-006870-f5w6fw6q 28 23 experienced experience VBD cord-006870-f5w6fw6q 28 24 a a DT cord-006870-f5w6fw6q 28 25 decrease decrease NN cord-006870-f5w6fw6q 28 26 in in IN cord-006870-f5w6fw6q 28 27 mRS mrs DT cord-006870-f5w6fw6q 28 28 score score NN cord-006870-f5w6fw6q 28 29 . . . cord-006870-f5w6fw6q 29 1 Improvement improvement NN cord-006870-f5w6fw6q 29 2 from from IN cord-006870-f5w6fw6q 29 3 initial initial JJ cord-006870-f5w6fw6q 29 4 treatment treatment NN cord-006870-f5w6fw6q 29 5 was be VBD cord-006870-f5w6fw6q 29 6 21 21 CD cord-006870-f5w6fw6q 29 7 % % NN cord-006870-f5w6fw6q 29 8 , , , cord-006870-f5w6fw6q 29 9 71 71 CD cord-006870-f5w6fw6q 29 10 % % NN cord-006870-f5w6fw6q 29 11 , , , cord-006870-f5w6fw6q 29 12 58 58 CD cord-006870-f5w6fw6q 29 13 % % NN cord-006870-f5w6fw6q 29 14 , , , cord-006870-f5w6fw6q 29 15 and and CC cord-006870-f5w6fw6q 29 16 80 80 CD cord-006870-f5w6fw6q 29 17 % % NN cord-006870-f5w6fw6q 29 18 for for IN cord-006870-f5w6fw6q 29 19 admitting admit VBG cord-006870-f5w6fw6q 29 20 mRS mrs PRP$ cord-006870-f5w6fw6q 29 21 scores score NNS cord-006870-f5w6fw6q 29 22 or or CC cord-006870-f5w6fw6q 29 23 2 2 CD cord-006870-f5w6fw6q 29 24 through through IN cord-006870-f5w6fw6q 29 25 5 5 CD cord-006870-f5w6fw6q 29 26 respectively respectively RB cord-006870-f5w6fw6q 29 27 . . . cord-006870-f5w6fw6q 30 1 The the DT cord-006870-f5w6fw6q 30 2 p p NN cord-006870-f5w6fw6q 30 3 - - HYPH cord-006870-f5w6fw6q 30 4 values value NNS cord-006870-f5w6fw6q 30 5 for for IN cord-006870-f5w6fw6q 30 6 improvement improvement NN cord-006870-f5w6fw6q 30 7 from from IN cord-006870-f5w6fw6q 30 8 initial initial JJ cord-006870-f5w6fw6q 30 9 immune immune JJ cord-006870-f5w6fw6q 30 10 therapy therapy NN cord-006870-f5w6fw6q 30 11 based base VBN cord-006870-f5w6fw6q 30 12 on on IN cord-006870-f5w6fw6q 30 13 an an DT cord-006870-f5w6fw6q 30 14 mRS mrs NN cord-006870-f5w6fw6q 30 15 of of IN cord-006870-f5w6fw6q 30 16 3 3 CD cord-006870-f5w6fw6q 30 17 , , , cord-006870-f5w6fw6q 30 18 4 4 CD cord-006870-f5w6fw6q 30 19 , , , cord-006870-f5w6fw6q 30 20 or or CC cord-006870-f5w6fw6q 30 21 5 5 CD cord-006870-f5w6fw6q 30 22 compared compare VBN cord-006870-f5w6fw6q 30 23 to to IN cord-006870-f5w6fw6q 30 24 an an DT cord-006870-f5w6fw6q 30 25 mRS mrs NN cord-006870-f5w6fw6q 30 26 of of IN cord-006870-f5w6fw6q 30 27 2 2 CD cord-006870-f5w6fw6q 30 28 were be VBD cord-006870-f5w6fw6q 30 29 0.0014 0.0014 CD cord-006870-f5w6fw6q 30 30 , , , cord-006870-f5w6fw6q 30 31 0.035 0.035 CD cord-006870-f5w6fw6q 30 32 , , , cord-006870-f5w6fw6q 30 33 and and CC cord-006870-f5w6fw6q 30 34 0.013 0.013 CD cord-006870-f5w6fw6q 30 35 respectively respectively RB cord-006870-f5w6fw6q 30 36 . . . cord-006870-f5w6fw6q 31 1 Immunosuppressive immunosuppressive JJ cord-006870-f5w6fw6q 31 2 therapies therapy NNS cord-006870-f5w6fw6q 31 3 for for IN cord-006870-f5w6fw6q 31 4 patients patient NNS cord-006870-f5w6fw6q 31 5 with with IN cord-006870-f5w6fw6q 31 6 an an DT cord-006870-f5w6fw6q 31 7 initial initial JJ cord-006870-f5w6fw6q 31 8 mRS mrs DT cord-006870-f5w6fw6q 31 9 score score NN cord-006870-f5w6fw6q 31 10 of of IN cord-006870-f5w6fw6q 31 11 3 3 CD cord-006870-f5w6fw6q 31 12 , , , cord-006870-f5w6fw6q 31 13 4 4 CD cord-006870-f5w6fw6q 31 14 or or CC cord-006870-f5w6fw6q 31 15 5 5 CD cord-006870-f5w6fw6q 31 16 may may MD cord-006870-f5w6fw6q 31 17 have have VB cord-006870-f5w6fw6q 31 18 a a DT cord-006870-f5w6fw6q 31 19 higher high JJR cord-006870-f5w6fw6q 31 20 yield yield NN cord-006870-f5w6fw6q 31 21 than than IN cord-006870-f5w6fw6q 31 22 for for IN cord-006870-f5w6fw6q 31 23 those those DT cord-006870-f5w6fw6q 31 24 with with IN cord-006870-f5w6fw6q 31 25 an an DT cord-006870-f5w6fw6q 31 26 mRS mrs NN cord-006870-f5w6fw6q 31 27 of of IN cord-006870-f5w6fw6q 31 28 2 2 CD cord-006870-f5w6fw6q 31 29 . . . cord-006870-f5w6fw6q 32 1 These these DT cord-006870-f5w6fw6q 32 2 therapies therapy NNS cord-006870-f5w6fw6q 32 3 are be VBP cord-006870-f5w6fw6q 32 4 generally generally RB cord-006870-f5w6fw6q 32 5 reserved reserve VBN cord-006870-f5w6fw6q 32 6 for for IN cord-006870-f5w6fw6q 32 7 those those DT cord-006870-f5w6fw6q 32 8 with with IN cord-006870-f5w6fw6q 32 9 an an DT cord-006870-f5w6fw6q 32 10 mRS mrs NN cord-006870-f5w6fw6q 32 11 of of IN cord-006870-f5w6fw6q 32 12 2 2 CD cord-006870-f5w6fw6q 32 13 or or CC cord-006870-f5w6fw6q 32 14 greater great JJR cord-006870-f5w6fw6q 32 15 . . . cord-006870-f5w6fw6q 33 1 Further further JJ cord-006870-f5w6fw6q 33 2 study study NN cord-006870-f5w6fw6q 33 3 is be VBZ cord-006870-f5w6fw6q 33 4 needed need VBN cord-006870-f5w6fw6q 33 5 to to TO cord-006870-f5w6fw6q 33 6 assess assess VB cord-006870-f5w6fw6q 33 7 functional functional JJ cord-006870-f5w6fw6q 33 8 improvement improvement NN cord-006870-f5w6fw6q 33 9 in in IN cord-006870-f5w6fw6q 33 10 those those DT cord-006870-f5w6fw6q 33 11 with with IN cord-006870-f5w6fw6q 33 12 autoimmune autoimmune NN cord-006870-f5w6fw6q 33 13 mediated mediate VBN cord-006870-f5w6fw6q 33 14 encephalitis encephalitis RB cord-006870-f5w6fw6q 33 15 treated treat VBN cord-006870-f5w6fw6q 33 16 with with IN cord-006870-f5w6fw6q 33 17 immunosuppressive immunosuppressive JJ cord-006870-f5w6fw6q 33 18 therapies therapy NNS cord-006870-f5w6fw6q 33 19 . . . cord-006870-f5w6fw6q 34 1 Many many JJ cord-006870-f5w6fw6q 34 2 patient patient NN cord-006870-f5w6fw6q 34 3 , , , cord-006870-f5w6fw6q 34 4 family family NN cord-006870-f5w6fw6q 34 5 and and CC cord-006870-f5w6fw6q 34 6 hospital hospital NN cord-006870-f5w6fw6q 34 7 factors factor NNS cord-006870-f5w6fw6q 34 8 have have VBP cord-006870-f5w6fw6q 34 9 been be VBN cord-006870-f5w6fw6q 34 10 associated associate VBN cord-006870-f5w6fw6q 34 11 with with IN cord-006870-f5w6fw6q 34 12 obtaining obtain VBG cord-006870-f5w6fw6q 34 13 consent consent NN cord-006870-f5w6fw6q 34 14 for for IN cord-006870-f5w6fw6q 34 15 organ organ NN cord-006870-f5w6fw6q 34 16 donation donation NN cord-006870-f5w6fw6q 34 17 after after IN cord-006870-f5w6fw6q 34 18 brain brain NN cord-006870-f5w6fw6q 34 19 death death NN cord-006870-f5w6fw6q 34 20 ( ( -LRB- cord-006870-f5w6fw6q 34 21 BD BD NNP cord-006870-f5w6fw6q 34 22 ) ) -RRB- cord-006870-f5w6fw6q 34 23 . . . cord-006870-f5w6fw6q 35 1 We -PRON- PRP cord-006870-f5w6fw6q 35 2 evaluated evaluate VBD cord-006870-f5w6fw6q 35 3 potential potential JJ cord-006870-f5w6fw6q 35 4 factors factor NNS cord-006870-f5w6fw6q 35 5 that that WDT cord-006870-f5w6fw6q 35 6 played play VBD cord-006870-f5w6fw6q 35 7 a a DT cord-006870-f5w6fw6q 35 8 role role NN cord-006870-f5w6fw6q 35 9 in in IN cord-006870-f5w6fw6q 35 10 the the DT cord-006870-f5w6fw6q 35 11 consent consent NN cord-006870-f5w6fw6q 35 12 rate rate NN cord-006870-f5w6fw6q 35 13 in in IN cord-006870-f5w6fw6q 35 14 a a DT cord-006870-f5w6fw6q 35 15 large large JJ cord-006870-f5w6fw6q 35 16 tertiary tertiary JJ cord-006870-f5w6fw6q 35 17 hospital hospital NN cord-006870-f5w6fw6q 35 18 over over IN cord-006870-f5w6fw6q 35 19 a a DT cord-006870-f5w6fw6q 35 20 period period NN cord-006870-f5w6fw6q 35 21 of of IN cord-006870-f5w6fw6q 35 22 11.5 11.5 CD cord-006870-f5w6fw6q 35 23 years year NNS cord-006870-f5w6fw6q 35 24 . . . cord-006870-f5w6fw6q 36 1 We -PRON- PRP cord-006870-f5w6fw6q 36 2 evaluated evaluate VBD cord-006870-f5w6fw6q 36 3 all all DT cord-006870-f5w6fw6q 36 4 declarations declaration NNS cord-006870-f5w6fw6q 36 5 in in IN cord-006870-f5w6fw6q 36 6 our -PRON- PRP$ cord-006870-f5w6fw6q 36 7 hospital hospital NN cord-006870-f5w6fw6q 36 8 's 's POS cord-006870-f5w6fw6q 36 9 BD BD NNP cord-006870-f5w6fw6q 36 10 registry registry NN cord-006870-f5w6fw6q 36 11 between between IN cord-006870-f5w6fw6q 36 12 January January NNP cord-006870-f5w6fw6q 36 13 2006 2006 CD cord-006870-f5w6fw6q 36 14 and and CC cord-006870-f5w6fw6q 36 15 June June NNP cord-006870-f5w6fw6q 36 16 2017 2017 CD cord-006870-f5w6fw6q 36 17 regarding regard VBG cord-006870-f5w6fw6q 36 18 consent consent NN cord-006870-f5w6fw6q 36 19 for for IN cord-006870-f5w6fw6q 36 20 donation donation NN cord-006870-f5w6fw6q 36 21 . . . cord-006870-f5w6fw6q 37 1 We -PRON- PRP cord-006870-f5w6fw6q 37 2 cross cross VBP cord-006870-f5w6fw6q 37 3 - - VBD cord-006870-f5w6fw6q 37 4 matched match VBD cord-006870-f5w6fw6q 37 5 the the DT cord-006870-f5w6fw6q 37 6 hospital hospital NN cord-006870-f5w6fw6q 37 7 electronic electronic JJ cord-006870-f5w6fw6q 37 8 medical medical JJ cord-006870-f5w6fw6q 37 9 records record NNS cord-006870-f5w6fw6q 37 10 with with IN cord-006870-f5w6fw6q 37 11 the the DT cord-006870-f5w6fw6q 37 12 records record NNS cord-006870-f5w6fw6q 37 13 of of IN cord-006870-f5w6fw6q 37 14 the the DT cord-006870-f5w6fw6q 37 15 local local JJ cord-006870-f5w6fw6q 37 16 organ organ NN cord-006870-f5w6fw6q 37 17 procurement procurement NN cord-006870-f5w6fw6q 37 18 organization organization NN cord-006870-f5w6fw6q 37 19 to to TO cord-006870-f5w6fw6q 37 20 identify identify VB cord-006870-f5w6fw6q 37 21 this this DT cord-006870-f5w6fw6q 37 22 population population NN cord-006870-f5w6fw6q 37 23 . . . cord-006870-f5w6fw6q 38 1 254 254 CD cord-006870-f5w6fw6q 38 2 patients patient NNS cord-006870-f5w6fw6q 38 3 were be VBD cord-006870-f5w6fw6q 38 4 included include VBN cord-006870-f5w6fw6q 38 5 in in IN cord-006870-f5w6fw6q 38 6 the the DT cord-006870-f5w6fw6q 38 7 registry registry NN cord-006870-f5w6fw6q 38 8 ( ( -LRB- cord-006870-f5w6fw6q 38 9 59 59 CD cord-006870-f5w6fw6q 38 10 . . . cord-006870-f5w6fw6q 38 11 5 5 CD cord-006870-f5w6fw6q 38 12 % % NN cord-006870-f5w6fw6q 38 13 African african JJ cord-006870-f5w6fw6q 38 14 American American NNP cord-006870-f5w6fw6q 38 15 ) ) -RRB- cord-006870-f5w6fw6q 38 16 and and CC cord-006870-f5w6fw6q 38 17 213 213 CD cord-006870-f5w6fw6q 38 18 were be VBD cord-006870-f5w6fw6q 38 19 approached approach VBN cord-006870-f5w6fw6q 38 20 for for IN cord-006870-f5w6fw6q 38 21 donation donation NN cord-006870-f5w6fw6q 38 22 . . . cord-006870-f5w6fw6q 39 1 There there EX cord-006870-f5w6fw6q 39 2 was be VBD cord-006870-f5w6fw6q 39 3 a a DT cord-006870-f5w6fw6q 39 4 71.8 71.8 CD cord-006870-f5w6fw6q 39 5 % % NN cord-006870-f5w6fw6q 39 6 consent consent NN cord-006870-f5w6fw6q 39 7 rate rate NN cord-006870-f5w6fw6q 39 8 for for IN cord-006870-f5w6fw6q 39 9 organ organ NN cord-006870-f5w6fw6q 39 10 donation donation NN cord-006870-f5w6fw6q 39 11 . . . cord-006870-f5w6fw6q 40 1 There there EX cord-006870-f5w6fw6q 40 2 was be VBD cord-006870-f5w6fw6q 40 3 no no DT cord-006870-f5w6fw6q 40 4 significant significant JJ cord-006870-f5w6fw6q 40 5 relationship relationship NN cord-006870-f5w6fw6q 40 6 between between IN cord-006870-f5w6fw6q 40 7 sex sex NN cord-006870-f5w6fw6q 40 8 , , , cord-006870-f5w6fw6q 40 9 admission admission NN cord-006870-f5w6fw6q 40 10 diagnosis diagnosis NN cord-006870-f5w6fw6q 40 11 , , , cord-006870-f5w6fw6q 40 12 ICU ICU NNP cord-006870-f5w6fw6q 40 13 ( ( -LRB- cord-006870-f5w6fw6q 40 14 neuro neuro NNP cord-006870-f5w6fw6q 40 15 vs. vs. FW cord-006870-f5w6fw6q 40 16 medical medical JJ cord-006870-f5w6fw6q 40 17 vs. vs. FW cord-006870-f5w6fw6q 40 18 surgical surgical JJ cord-006870-f5w6fw6q 40 19 ) ) -RRB- cord-006870-f5w6fw6q 40 20 , , , cord-006870-f5w6fw6q 40 21 physician physician NN cord-006870-f5w6fw6q 40 22 specialty specialty NN cord-006870-f5w6fw6q 40 23 ( ( -LRB- cord-006870-f5w6fw6q 40 24 neurology neurology NN cord-006870-f5w6fw6q 40 25 vs. vs. IN cord-006870-f5w6fw6q 40 26 other other JJ cord-006870-f5w6fw6q 40 27 ) ) -RRB- cord-006870-f5w6fw6q 40 28 , , , cord-006870-f5w6fw6q 40 29 time time NN cord-006870-f5w6fw6q 40 30 from from IN cord-006870-f5w6fw6q 40 31 event event NN cord-006870-f5w6fw6q 40 32 to to IN cord-006870-f5w6fw6q 40 33 BD BD NNP cord-006870-f5w6fw6q 40 34 declaration declaration NN cord-006870-f5w6fw6q 40 35 or or CC cord-006870-f5w6fw6q 40 36 religion religion NN cord-006870-f5w6fw6q 40 37 and and CC cord-006870-f5w6fw6q 40 38 decision decision NN cord-006870-f5w6fw6q 40 39 to to TO cord-006870-f5w6fw6q 40 40 donate donate VB cord-006870-f5w6fw6q 40 41 . . . cord-006870-f5w6fw6q 41 1 Families family NNS cord-006870-f5w6fw6q 41 2 were be VBD cord-006870-f5w6fw6q 41 3 more more RBR cord-006870-f5w6fw6q 41 4 likely likely JJ cord-006870-f5w6fw6q 41 5 to to TO cord-006870-f5w6fw6q 41 6 consent consent VB cord-006870-f5w6fw6q 41 7 to to IN cord-006870-f5w6fw6q 41 8 donation donation NN cord-006870-f5w6fw6q 41 9 if if IN cord-006870-f5w6fw6q 41 10 the the DT cord-006870-f5w6fw6q 41 11 patient patient NN cord-006870-f5w6fw6q 41 12 was be VBD cord-006870-f5w6fw6q 41 13 non non JJ cord-006870-f5w6fw6q 41 14 - - JJ cord-006870-f5w6fw6q 41 15 AA aa JJ cord-006870-f5w6fw6q 41 16 ( ( -LRB- cord-006870-f5w6fw6q 41 17 88 88 CD cord-006870-f5w6fw6q 41 18 % % NN cord-006870-f5w6fw6q 41 19 vs vs IN cord-006870-f5w6fw6q 41 20 62 62 CD cord-006870-f5w6fw6q 41 21 % % NN cord-006870-f5w6fw6q 41 22 for for IN cord-006870-f5w6fw6q 41 23 AA AA NNP cord-006870-f5w6fw6q 41 24 , , , cord-006870-f5w6fw6q 41 25 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 41 26 ) ) -RRB- cord-006870-f5w6fw6q 41 27 , , , cord-006870-f5w6fw6q 41 28 was be VBD cord-006870-f5w6fw6q 41 29 younger young JJR cord-006870-f5w6fw6q 41 30 ( ( -LRB- cord-006870-f5w6fw6q 41 31 46.5 46.5 CD cord-006870-f5w6fw6q 41 32 vs vs IN cord-006870-f5w6fw6q 41 33 52.4 52.4 CD cord-006870-f5w6fw6q 41 34 , , , cord-006870-f5w6fw6q 41 35 p=0.026 p=0.026 NNP cord-006870-f5w6fw6q 41 36 ) ) -RRB- cord-006870-f5w6fw6q 41 37 , , , cord-006870-f5w6fw6q 41 38 had have VBD cord-006870-f5w6fw6q 41 39 a a DT cord-006870-f5w6fw6q 41 40 lower low JJR cord-006870-f5w6fw6q 41 41 creatinine creatinine NN cord-006870-f5w6fw6q 41 42 at at IN cord-006870-f5w6fw6q 41 43 the the DT cord-006870-f5w6fw6q 41 44 time time NN cord-006870-f5w6fw6q 41 45 of of IN cord-006870-f5w6fw6q 41 46 death death NN cord-006870-f5w6fw6q 41 47 ( ( -LRB- cord-006870-f5w6fw6q 41 48 1.7 1.7 CD cord-006870-f5w6fw6q 41 49 ± ± CD cord-006870-f5w6fw6q 41 50 1.9 1.9 CD cord-006870-f5w6fw6q 41 51 vs vs IN cord-006870-f5w6fw6q 41 52 2.4 2.4 CD cord-006870-f5w6fw6q 41 53 ± ± CD cord-006870-f5w6fw6q 41 54 2.3 2.3 CD cord-006870-f5w6fw6q 42 1 mg mg NNP cord-006870-f5w6fw6q 42 2 / / SYM cord-006870-f5w6fw6q 42 3 dL dl NN cord-006870-f5w6fw6q 42 4 , , , cord-006870-f5w6fw6q 42 5 p=0.015 p=0.015 NNPS cord-006870-f5w6fw6q 42 6 ) ) -RRB- cord-006870-f5w6fw6q 42 7 , , , cord-006870-f5w6fw6q 42 8 and and CC cord-006870-f5w6fw6q 42 9 had have VBD cord-006870-f5w6fw6q 42 10 an an DT cord-006870-f5w6fw6q 42 11 apnea apnea NN cord-006870-f5w6fw6q 42 12 test test NN cord-006870-f5w6fw6q 42 13 completed complete VBN cord-006870-f5w6fw6q 42 14 ( ( -LRB- cord-006870-f5w6fw6q 42 15 74 74 CD cord-006870-f5w6fw6q 42 16 % % NN cord-006870-f5w6fw6q 42 17 vs vs IN cord-006870-f5w6fw6q 42 18 50 50 CD cord-006870-f5w6fw6q 42 19 % % NN cord-006870-f5w6fw6q 42 20 , , , cord-006870-f5w6fw6q 42 21 p=0.017 p=0.017 NNS cord-006870-f5w6fw6q 42 22 ) ) -RRB- cord-006870-f5w6fw6q 42 23 . . . cord-006870-f5w6fw6q 43 1 In in IN cord-006870-f5w6fw6q 43 2 a a DT cord-006870-f5w6fw6q 43 3 logistic logistic JJ cord-006870-f5w6fw6q 43 4 regression regression NN cord-006870-f5w6fw6q 43 5 model model NN cord-006870-f5w6fw6q 43 6 , , , cord-006870-f5w6fw6q 43 7 only only RB cord-006870-f5w6fw6q 43 8 AA AA NNP cord-006870-f5w6fw6q 43 9 race race NN cord-006870-f5w6fw6q 43 10 and and CC cord-006870-f5w6fw6q 43 11 PaO2 PaO2 NNS cord-006870-f5w6fw6q 43 12 independently independently RB cord-006870-f5w6fw6q 43 13 predicted predict VBD cord-006870-f5w6fw6q 43 14 refusal refusal NN cord-006870-f5w6fw6q 43 15 of of IN cord-006870-f5w6fw6q 43 16 donation donation NN cord-006870-f5w6fw6q 43 17 ( ( -LRB- cord-006870-f5w6fw6q 43 18 odds odd NNS cord-006870-f5w6fw6q 43 19 , , , cord-006870-f5w6fw6q 43 20 95%CI 95%ci CD cord-006870-f5w6fw6q 43 21 , , , cord-006870-f5w6fw6q 43 22 5.3 5.3 CD cord-006870-f5w6fw6q 43 23 , , , cord-006870-f5w6fw6q 43 24 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 43 25 and and CC cord-006870-f5w6fw6q 43 26 0.84 0.84 CD cord-006870-f5w6fw6q 43 27 , , , cord-006870-f5w6fw6q 43 28 p= p= NNP cord-006870-f5w6fw6q 43 29 0.017 0.017 CD cord-006870-f5w6fw6q 43 30 , , , cord-006870-f5w6fw6q 43 31 respectively respectively RB cord-006870-f5w6fw6q 43 32 ) ) -RRB- cord-006870-f5w6fw6q 43 33 . . . cord-006870-f5w6fw6q 44 1 Although although IN cord-006870-f5w6fw6q 44 2 the the DT cord-006870-f5w6fw6q 44 3 majority majority NN cord-006870-f5w6fw6q 44 4 of of IN cord-006870-f5w6fw6q 44 5 BD BD NNP cord-006870-f5w6fw6q 44 6 patients patient NNS cord-006870-f5w6fw6q 44 7 in in IN cord-006870-f5w6fw6q 44 8 this this DT cord-006870-f5w6fw6q 44 9 large large JJ cord-006870-f5w6fw6q 44 10 series series NN cord-006870-f5w6fw6q 44 11 were be VBD cord-006870-f5w6fw6q 44 12 AA AA NNP cord-006870-f5w6fw6q 44 13 , , , cord-006870-f5w6fw6q 44 14 their -PRON- PRP$ cord-006870-f5w6fw6q 44 15 families family NNS cord-006870-f5w6fw6q 44 16 were be VBD cord-006870-f5w6fw6q 44 17 5 5 CD cord-006870-f5w6fw6q 44 18 times time NNS cord-006870-f5w6fw6q 44 19 less less RBR cord-006870-f5w6fw6q 44 20 likely likely JJ cord-006870-f5w6fw6q 44 21 to to TO cord-006870-f5w6fw6q 44 22 consent consent VB cord-006870-f5w6fw6q 44 23 for for IN cord-006870-f5w6fw6q 44 24 organ organ NN cord-006870-f5w6fw6q 44 25 donation donation NN cord-006870-f5w6fw6q 44 26 than than IN cord-006870-f5w6fw6q 44 27 non non JJ cord-006870-f5w6fw6q 44 28 - - JJ cord-006870-f5w6fw6q 44 29 AA aa JJ cord-006870-f5w6fw6q 44 30 families family NNS cord-006870-f5w6fw6q 44 31 . . . cord-006870-f5w6fw6q 45 1 There there EX cord-006870-f5w6fw6q 45 2 is be VBZ cord-006870-f5w6fw6q 45 3 an an DT cord-006870-f5w6fw6q 45 4 urgent urgent JJ cord-006870-f5w6fw6q 45 5 need need NN cord-006870-f5w6fw6q 45 6 to to TO cord-006870-f5w6fw6q 45 7 explore explore VB cord-006870-f5w6fw6q 45 8 the the DT cord-006870-f5w6fw6q 45 9 reasons reason NNS cord-006870-f5w6fw6q 45 10 for for IN cord-006870-f5w6fw6q 45 11 low low JJ cord-006870-f5w6fw6q 45 12 donation donation NN cord-006870-f5w6fw6q 45 13 rates rate NNS cord-006870-f5w6fw6q 45 14 in in IN cord-006870-f5w6fw6q 45 15 this this DT cord-006870-f5w6fw6q 45 16 population population NN cord-006870-f5w6fw6q 45 17 . . . cord-006870-f5w6fw6q 46 1 Post post JJ cord-006870-f5w6fw6q 46 2 - - JJ cord-006870-f5w6fw6q 46 3 anoxic anoxic JJ cord-006870-f5w6fw6q 46 4 myoclonus myoclonus NN cord-006870-f5w6fw6q 46 5 is be VBZ cord-006870-f5w6fw6q 46 6 seen see VBN cord-006870-f5w6fw6q 46 7 in in IN cord-006870-f5w6fw6q 46 8 up up IN cord-006870-f5w6fw6q 46 9 to to TO cord-006870-f5w6fw6q 46 10 20 20 CD cord-006870-f5w6fw6q 46 11 % % NN cord-006870-f5w6fw6q 46 12 of of IN cord-006870-f5w6fw6q 46 13 patients patient NNS cord-006870-f5w6fw6q 46 14 who who WP cord-006870-f5w6fw6q 46 15 remain remain VBP cord-006870-f5w6fw6q 46 16 comatose comatose JJ cord-006870-f5w6fw6q 46 17 , , , cord-006870-f5w6fw6q 46 18 and and CC cord-006870-f5w6fw6q 46 19 historically historically RB cord-006870-f5w6fw6q 46 20 was be VBD cord-006870-f5w6fw6q 46 21 felt feel VBN cord-006870-f5w6fw6q 46 22 to to TO cord-006870-f5w6fw6q 46 23 be be VB cord-006870-f5w6fw6q 46 24 a a DT cord-006870-f5w6fw6q 46 25 poor poor JJ cord-006870-f5w6fw6q 46 26 prognostic prognostic JJ cord-006870-f5w6fw6q 46 27 sign sign NN cord-006870-f5w6fw6q 46 28 . . . cord-006870-f5w6fw6q 47 1 Little little JJ cord-006870-f5w6fw6q 47 2 distinction distinction NN cord-006870-f5w6fw6q 47 3 has have VBZ cord-006870-f5w6fw6q 47 4 been be VBN cord-006870-f5w6fw6q 47 5 made make VBN cord-006870-f5w6fw6q 47 6 in in IN cord-006870-f5w6fw6q 47 7 the the DT cord-006870-f5w6fw6q 47 8 literature literature NN cord-006870-f5w6fw6q 47 9 between between IN cord-006870-f5w6fw6q 47 10 epileptic epileptic JJ cord-006870-f5w6fw6q 47 11 ( ( -LRB- cord-006870-f5w6fw6q 47 12 cortical cortical JJ cord-006870-f5w6fw6q 47 13 ) ) -RRB- cord-006870-f5w6fw6q 47 14 vs vs IN cord-006870-f5w6fw6q 47 15 subcortical subcortical JJ cord-006870-f5w6fw6q 47 16 myoclonus myoclonus NN cord-006870-f5w6fw6q 47 17 . . . cord-006870-f5w6fw6q 48 1 From from IN cord-006870-f5w6fw6q 48 2 604 604 CD cord-006870-f5w6fw6q 48 3 consecutive consecutive JJ cord-006870-f5w6fw6q 48 4 cardiac cardiac JJ cord-006870-f5w6fw6q 48 5 arrest arrest NN cord-006870-f5w6fw6q 48 6 patients patient NNS cord-006870-f5w6fw6q 48 7 that that WDT cord-006870-f5w6fw6q 48 8 did do VBD cord-006870-f5w6fw6q 48 9 not not RB cord-006870-f5w6fw6q 48 10 return return VB cord-006870-f5w6fw6q 48 11 to to IN cord-006870-f5w6fw6q 48 12 baseline baseline NN cord-006870-f5w6fw6q 48 13 ( ( -LRB- cord-006870-f5w6fw6q 48 14 May May NNP cord-006870-f5w6fw6q 48 15 2007-May 2007-may CD cord-006870-f5w6fw6q 48 16 2016 2016 CD cord-006870-f5w6fw6q 48 17 ) ) -RRB- cord-006870-f5w6fw6q 48 18 we -PRON- PRP cord-006870-f5w6fw6q 48 19 identified identify VBD cord-006870-f5w6fw6q 48 20 18 18 CD cord-006870-f5w6fw6q 48 21 % % NN cord-006870-f5w6fw6q 48 22 ( ( -LRB- cord-006870-f5w6fw6q 48 23 N=111 n=111 NN cord-006870-f5w6fw6q 48 24 ) ) -RRB- cord-006870-f5w6fw6q 48 25 patients patient NNS cord-006870-f5w6fw6q 48 26 with with IN cord-006870-f5w6fw6q 48 27 clinical clinical JJ cord-006870-f5w6fw6q 48 28 myoclonus myoclonus NN cord-006870-f5w6fw6q 48 29 . . . cord-006870-f5w6fw6q 49 1 Basic basic JJ cord-006870-f5w6fw6q 49 2 demographics demographic NNS cord-006870-f5w6fw6q 49 3 and and CC cord-006870-f5w6fw6q 49 4 characteristics characteristic NNS cord-006870-f5w6fw6q 49 5 of of IN cord-006870-f5w6fw6q 49 6 their -PRON- PRP$ cord-006870-f5w6fw6q 49 7 arrest arrest NN cord-006870-f5w6fw6q 49 8 were be VBD cord-006870-f5w6fw6q 49 9 collected collect VBN cord-006870-f5w6fw6q 49 10 and and CC cord-006870-f5w6fw6q 49 11 EEG EEG NNP cord-006870-f5w6fw6q 49 12 reports report NNS cord-006870-f5w6fw6q 49 13 were be VBD cord-006870-f5w6fw6q 49 14 reviewed review VBN cord-006870-f5w6fw6q 49 15 . . . cord-006870-f5w6fw6q 50 1 Raw Raw NNP cord-006870-f5w6fw6q 50 2 EEG EEG NNP cord-006870-f5w6fw6q 50 3 including include VBG cord-006870-f5w6fw6q 50 4 video video NN cord-006870-f5w6fw6q 50 5 was be VBD cord-006870-f5w6fw6q 50 6 reviewed review VBN cord-006870-f5w6fw6q 50 7 by by IN cord-006870-f5w6fw6q 50 8 two two CD cord-006870-f5w6fw6q 50 9 epilepsy epilepsy NN cord-006870-f5w6fw6q 50 10 - - HYPH cord-006870-f5w6fw6q 50 11 trained train VBN cord-006870-f5w6fw6q 50 12 neurologists neurologist NNS cord-006870-f5w6fw6q 50 13 , , , cord-006870-f5w6fw6q 50 14 whenever whenever WRB cord-006870-f5w6fw6q 50 15 available available JJ cord-006870-f5w6fw6q 50 16 . . . cord-006870-f5w6fw6q 51 1 Myoclonus Myoclonus NNP cord-006870-f5w6fw6q 51 2 was be VBD cord-006870-f5w6fw6q 51 3 subcategorized subcategorize VBN cord-006870-f5w6fw6q 51 4 into into IN cord-006870-f5w6fw6q 51 5 subcortical subcortical JJ cord-006870-f5w6fw6q 51 6 and and CC cord-006870-f5w6fw6q 51 7 cortical cortical JJ cord-006870-f5w6fw6q 51 8 based base VBN cord-006870-f5w6fw6q 51 9 on on IN cord-006870-f5w6fw6q 51 10 the the DT cord-006870-f5w6fw6q 51 11 presence presence NN cord-006870-f5w6fw6q 51 12 of of IN cord-006870-f5w6fw6q 51 13 a a DT cord-006870-f5w6fw6q 51 14 preceding precede VBG cord-006870-f5w6fw6q 51 15 EEG EEG NNP cord-006870-f5w6fw6q 51 16 correlate correlate VB cord-006870-f5w6fw6q 51 17 . . . cord-006870-f5w6fw6q 52 1 Jerk jerk NN cord-006870-f5w6fw6q 52 2 - - HYPH cord-006870-f5w6fw6q 52 3 locked lock VBN cord-006870-f5w6fw6q 52 4 EEG EEG NNP cord-006870-f5w6fw6q 52 5 back back RB cord-006870-f5w6fw6q 52 6 - - HYPH cord-006870-f5w6fw6q 52 7 averaging averaging NN cord-006870-f5w6fw6q 52 8 was be VBD cord-006870-f5w6fw6q 52 9 performed perform VBN cord-006870-f5w6fw6q 52 10 on on IN cord-006870-f5w6fw6q 52 11 two two CD cord-006870-f5w6fw6q 52 12 representative representative JJ cord-006870-f5w6fw6q 52 13 patients patient NNS cord-006870-f5w6fw6q 52 14 . . . cord-006870-f5w6fw6q 53 1 The the DT cord-006870-f5w6fw6q 53 2 average average JJ cord-006870-f5w6fw6q 53 3 age age NN cord-006870-f5w6fw6q 53 4 of of IN cord-006870-f5w6fw6q 53 5 patients patient NNS cord-006870-f5w6fw6q 53 6 with with IN cord-006870-f5w6fw6q 53 7 myoclonus myoclonus NN cord-006870-f5w6fw6q 53 8 was be VBD cord-006870-f5w6fw6q 53 9 63+/-17 63+/-17 CD cord-006870-f5w6fw6q 53 10 years year NNS cord-006870-f5w6fw6q 53 11 , , , cord-006870-f5w6fw6q 53 12 and and CC cord-006870-f5w6fw6q 53 13 29 29 CD cord-006870-f5w6fw6q 53 14 % % NN cord-006870-f5w6fw6q 53 15 ( ( -LRB- cord-006870-f5w6fw6q 53 16 N=32 N=32 NNP cord-006870-f5w6fw6q 53 17 ) ) -RRB- cord-006870-f5w6fw6q 53 18 survived survive VBD cord-006870-f5w6fw6q 53 19 to to TO cord-006870-f5w6fw6q 53 20 discharge discharge VB cord-006870-f5w6fw6q 53 21 . . . cord-006870-f5w6fw6q 54 1 Cortical cortical JJ cord-006870-f5w6fw6q 54 2 myoclonus myoclonus NN cord-006870-f5w6fw6q 54 3 was be VBD cord-006870-f5w6fw6q 54 4 twice twice RB cord-006870-f5w6fw6q 54 5 as as RB cord-006870-f5w6fw6q 54 6 likely likely JJ cord-006870-f5w6fw6q 54 7 as as IN cord-006870-f5w6fw6q 54 8 subcortical subcortical JJ cord-006870-f5w6fw6q 54 9 myoclonus myoclonus NN cord-006870-f5w6fw6q 54 10 ( ( -LRB- cord-006870-f5w6fw6q 54 11 59 59 CD cord-006870-f5w6fw6q 54 12 % % NN cord-006870-f5w6fw6q 54 13 vs vs IN cord-006870-f5w6fw6q 54 14 23 23 CD cord-006870-f5w6fw6q 54 15 % % NN cord-006870-f5w6fw6q 54 16 , , , cord-006870-f5w6fw6q 54 17 respectively respectively RB cord-006870-f5w6fw6q 54 18 ) ) -RRB- cord-006870-f5w6fw6q 54 19 . . . cord-006870-f5w6fw6q 55 1 Compared compare VBN cord-006870-f5w6fw6q 55 2 with with IN cord-006870-f5w6fw6q 55 3 493 493 CD cord-006870-f5w6fw6q 55 4 patients patient NNS cord-006870-f5w6fw6q 55 5 without without IN cord-006870-f5w6fw6q 55 6 myoclonus myoclonus NN cord-006870-f5w6fw6q 55 7 , , , cord-006870-f5w6fw6q 55 8 patients patient NNS cord-006870-f5w6fw6q 55 9 with with IN cord-006870-f5w6fw6q 55 10 myoclonus myoclonus NN cord-006870-f5w6fw6q 55 11 were be VBD cord-006870-f5w6fw6q 55 12 more more RBR cord-006870-f5w6fw6q 55 13 likely likely JJ cord-006870-f5w6fw6q 55 14 to to TO cord-006870-f5w6fw6q 55 15 have have VB cord-006870-f5w6fw6q 55 16 longer long JJR cord-006870-f5w6fw6q 55 17 , , , cord-006870-f5w6fw6q 55 18 more more RBR cord-006870-f5w6fw6q 55 19 severe severe JJ cord-006870-f5w6fw6q 55 20 arrests arrest NNS cord-006870-f5w6fw6q 55 21 . . . cord-006870-f5w6fw6q 56 1 Patients patient NNS cord-006870-f5w6fw6q 56 2 with with IN cord-006870-f5w6fw6q 56 3 subcortical subcortical JJ cord-006870-f5w6fw6q 56 4 myoclonus myoclonu NNS cord-006870-f5w6fw6q 56 5 were be VBD cord-006870-f5w6fw6q 56 6 at at IN cord-006870-f5w6fw6q 56 7 risk risk NN cord-006870-f5w6fw6q 56 8 for for IN cord-006870-f5w6fw6q 56 9 electrographic electrographic JJ cord-006870-f5w6fw6q 56 10 seizures seizure NNS cord-006870-f5w6fw6q 56 11 , , , cord-006870-f5w6fw6q 56 12 although although IN cord-006870-f5w6fw6q 56 13 at at IN cord-006870-f5w6fw6q 56 14 a a DT cord-006870-f5w6fw6q 56 15 lower low JJR cord-006870-f5w6fw6q 56 16 rate rate NN cord-006870-f5w6fw6q 56 17 than than IN cord-006870-f5w6fw6q 56 18 those those DT cord-006870-f5w6fw6q 56 19 with with IN cord-006870-f5w6fw6q 56 20 cortical cortical JJ cord-006870-f5w6fw6q 56 21 myoclonus myoclonus NN cord-006870-f5w6fw6q 56 22 ( ( -LRB- cord-006870-f5w6fw6q 56 23 8 8 CD cord-006870-f5w6fw6q 56 24 % % NN cord-006870-f5w6fw6q 56 25 vs vs IN cord-006870-f5w6fw6q 56 26 43 43 CD cord-006870-f5w6fw6q 56 27 % % NN cord-006870-f5w6fw6q 56 28 , , , cord-006870-f5w6fw6q 56 29 respectively respectively RB cord-006870-f5w6fw6q 56 30 ) ) -RRB- cord-006870-f5w6fw6q 56 31 . . . cord-006870-f5w6fw6q 57 1 Mortality mortality NN cord-006870-f5w6fw6q 57 2 rates rate NNS cord-006870-f5w6fw6q 57 3 did do VBD cord-006870-f5w6fw6q 57 4 not not RB cord-006870-f5w6fw6q 57 5 differ differ VB cord-006870-f5w6fw6q 57 6 between between IN cord-006870-f5w6fw6q 57 7 patients patient NNS cord-006870-f5w6fw6q 57 8 with with IN cord-006870-f5w6fw6q 57 9 cortical cortical JJ cord-006870-f5w6fw6q 57 10 and and CC cord-006870-f5w6fw6q 57 11 subcortical subcortical JJ cord-006870-f5w6fw6q 57 12 myoclonus myoclonus NN cord-006870-f5w6fw6q 57 13 ( ( -LRB- cord-006870-f5w6fw6q 57 14 74 74 CD cord-006870-f5w6fw6q 57 15 % % NN cord-006870-f5w6fw6q 57 16 vs vs IN cord-006870-f5w6fw6q 57 17 76 76 CD cord-006870-f5w6fw6q 57 18 % % NN cord-006870-f5w6fw6q 57 19 ) ) -RRB- cord-006870-f5w6fw6q 57 20 . . . cord-006870-f5w6fw6q 58 1 Patients patient NNS cord-006870-f5w6fw6q 58 2 with with IN cord-006870-f5w6fw6q 58 3 cortical cortical JJ cord-006870-f5w6fw6q 58 4 myoclonus myoclonu NNS cord-006870-f5w6fw6q 58 5 were be VBD cord-006870-f5w6fw6q 58 6 more more RBR cord-006870-f5w6fw6q 58 7 likely likely JJ cord-006870-f5w6fw6q 58 8 to to TO cord-006870-f5w6fw6q 58 9 be be VB cord-006870-f5w6fw6q 58 10 discharged discharge VBN cord-006870-f5w6fw6q 58 11 in in IN cord-006870-f5w6fw6q 58 12 a a DT cord-006870-f5w6fw6q 58 13 vegetative vegetative JJ cord-006870-f5w6fw6q 58 14 state state NN cord-006870-f5w6fw6q 58 15 compared compare VBN cord-006870-f5w6fw6q 58 16 to to IN cord-006870-f5w6fw6q 58 17 those those DT cord-006870-f5w6fw6q 58 18 with with IN cord-006870-f5w6fw6q 58 19 subcortical subcortical JJ cord-006870-f5w6fw6q 58 20 myoclonus myoclonus NN cord-006870-f5w6fw6q 58 21 ( ( -LRB- cord-006870-f5w6fw6q 58 22 82 82 CD cord-006870-f5w6fw6q 58 23 % % NN cord-006870-f5w6fw6q 58 24 vs vs IN cord-006870-f5w6fw6q 58 25 33 33 CD cord-006870-f5w6fw6q 58 26 % % NN cord-006870-f5w6fw6q 58 27 , , , cord-006870-f5w6fw6q 58 28 respectively respectively RB cord-006870-f5w6fw6q 58 29 ( ( -LRB- cord-006870-f5w6fw6q 58 30 OR or CC cord-006870-f5w6fw6q 58 31 9.3 9.3 CD cord-006870-f5w6fw6q 58 32 ; ; : cord-006870-f5w6fw6q 58 33 95%CI 95%ci CD cord-006870-f5w6fw6q 58 34 1.1 1.1 CD cord-006870-f5w6fw6q 58 35 - - HYPH cord-006870-f5w6fw6q 58 36 76.7 76.7 CD cord-006870-f5w6fw6q 58 37 ) ) -RRB- cord-006870-f5w6fw6q 58 38 . . . cord-006870-f5w6fw6q 59 1 Amongst amongst IN cord-006870-f5w6fw6q 59 2 survivors survivor NNS cord-006870-f5w6fw6q 59 3 , , , cord-006870-f5w6fw6q 59 4 good good JJ cord-006870-f5w6fw6q 59 5 functional functional JJ cord-006870-f5w6fw6q 59 6 outcome outcome NN cord-006870-f5w6fw6q 59 7 at at IN cord-006870-f5w6fw6q 59 8 discharge discharge NN cord-006870-f5w6fw6q 59 9 did do VBD cord-006870-f5w6fw6q 59 10 not not RB cord-006870-f5w6fw6q 59 11 differ differ VB cord-006870-f5w6fw6q 59 12 between between IN cord-006870-f5w6fw6q 59 13 cortical cortical JJ cord-006870-f5w6fw6q 59 14 vs vs IN cord-006870-f5w6fw6q 59 15 subcortical subcortical JJ cord-006870-f5w6fw6q 59 16 myoclonus myoclonus NN cord-006870-f5w6fw6q 59 17 ( ( -LRB- cord-006870-f5w6fw6q 59 18 12 12 CD cord-006870-f5w6fw6q 59 19 vs vs IN cord-006870-f5w6fw6q 59 20 16 16 CD cord-006870-f5w6fw6q 59 21 % % NN cord-006870-f5w6fw6q 59 22 , , , cord-006870-f5w6fw6q 59 23 respectively respectively RB cord-006870-f5w6fw6q 59 24 ) ) -RRB- cord-006870-f5w6fw6q 59 25 . . . cord-006870-f5w6fw6q 60 1 Jerk jerk NN cord-006870-f5w6fw6q 60 2 - - HYPH cord-006870-f5w6fw6q 60 3 locked lock VBN cord-006870-f5w6fw6q 60 4 EEG EEG NNP cord-006870-f5w6fw6q 60 5 back back RB cord-006870-f5w6fw6q 60 6 - - HYPH cord-006870-f5w6fw6q 60 7 averaging averaging NN cord-006870-f5w6fw6q 60 8 was be VBD cord-006870-f5w6fw6q 60 9 useful useful JJ cord-006870-f5w6fw6q 60 10 in in IN cord-006870-f5w6fw6q 60 11 distinguishing distinguish VBG cord-006870-f5w6fw6q 60 12 subcortical subcortical JJ cord-006870-f5w6fw6q 60 13 from from IN cord-006870-f5w6fw6q 60 14 cortical cortical JJ cord-006870-f5w6fw6q 60 15 myoclonus myoclonus NN cord-006870-f5w6fw6q 60 16 . . . cord-006870-f5w6fw6q 61 1 Myoclonus Myoclonus NNP cord-006870-f5w6fw6q 61 2 is be VBZ cord-006870-f5w6fw6q 61 3 seen see VBN cord-006870-f5w6fw6q 61 4 in in IN cord-006870-f5w6fw6q 61 5 every every DT cord-006870-f5w6fw6q 61 6 sixth sixth JJ cord-006870-f5w6fw6q 61 7 patient patient NN cord-006870-f5w6fw6q 61 8 with with IN cord-006870-f5w6fw6q 61 9 cardiac cardiac JJ cord-006870-f5w6fw6q 61 10 arrest arrest NN cord-006870-f5w6fw6q 61 11 . . . cord-006870-f5w6fw6q 62 1 Cortical cortical JJ cord-006870-f5w6fw6q 62 2 and and CC cord-006870-f5w6fw6q 62 3 subcortical subcortical JJ cord-006870-f5w6fw6q 62 4 myoclonus myoclonus NN cord-006870-f5w6fw6q 62 5 can can MD cord-006870-f5w6fw6q 62 6 not not RB cord-006870-f5w6fw6q 62 7 be be VB cord-006870-f5w6fw6q 62 8 distinguished distinguish VBN cord-006870-f5w6fw6q 62 9 using use VBG cord-006870-f5w6fw6q 62 10 clinical clinical JJ cord-006870-f5w6fw6q 62 11 criteria criterion NNS cord-006870-f5w6fw6q 62 12 . . . cord-006870-f5w6fw6q 63 1 Both both DT cord-006870-f5w6fw6q 63 2 may may MD cord-006870-f5w6fw6q 63 3 have have VB cord-006870-f5w6fw6q 63 4 good good JJ cord-006870-f5w6fw6q 63 5 outcomes outcome NNS cord-006870-f5w6fw6q 63 6 when when WRB cord-006870-f5w6fw6q 63 7 managed manage VBN cord-006870-f5w6fw6q 63 8 with with IN cord-006870-f5w6fw6q 63 9 targeted target VBN cord-006870-f5w6fw6q 63 10 temperature temperature NN cord-006870-f5w6fw6q 63 11 management management NN cord-006870-f5w6fw6q 63 12 and and CC cord-006870-f5w6fw6q 63 13 an an DT cord-006870-f5w6fw6q 63 14 aggressive aggressive JJ cord-006870-f5w6fw6q 63 15 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 63 16 regimen regimen NN cord-006870-f5w6fw6q 63 17 . . . cord-006870-f5w6fw6q 64 1 Intoxication intoxication NN cord-006870-f5w6fw6q 64 2 by by IN cord-006870-f5w6fw6q 64 3 central central JJ cord-006870-f5w6fw6q 64 4 nervous nervous JJ cord-006870-f5w6fw6q 64 5 system system NN cord-006870-f5w6fw6q 65 1 ( ( -LRB- cord-006870-f5w6fw6q 65 2 CNS CNS NNP cord-006870-f5w6fw6q 65 3 ) ) -RRB- cord-006870-f5w6fw6q 65 4 depressant depressant JJ cord-006870-f5w6fw6q 65 5 drugs drug NNS cord-006870-f5w6fw6q 65 6 can can MD cord-006870-f5w6fw6q 65 7 lead lead VB cord-006870-f5w6fw6q 65 8 to to IN cord-006870-f5w6fw6q 65 9 anoxic anoxic JJ cord-006870-f5w6fw6q 65 10 brain brain NN cord-006870-f5w6fw6q 65 11 injury injury NN cord-006870-f5w6fw6q 65 12 by by IN cord-006870-f5w6fw6q 65 13 cardiac cardiac JJ cord-006870-f5w6fw6q 65 14 or or CC cord-006870-f5w6fw6q 65 15 respiratory respiratory JJ cord-006870-f5w6fw6q 65 16 arrest arrest NN cord-006870-f5w6fw6q 65 17 . . . cord-006870-f5w6fw6q 66 1 We -PRON- PRP cord-006870-f5w6fw6q 66 2 tested test VBD cord-006870-f5w6fw6q 66 3 the the DT cord-006870-f5w6fw6q 66 4 hypothesis hypothesis NN cord-006870-f5w6fw6q 66 5 whether whether IN cord-006870-f5w6fw6q 66 6 intoxication intoxication NN cord-006870-f5w6fw6q 66 7 by by IN cord-006870-f5w6fw6q 66 8 these these DT cord-006870-f5w6fw6q 66 9 drugs drug NNS cord-006870-f5w6fw6q 66 10 contributes contribute VBZ cord-006870-f5w6fw6q 66 11 to to IN cord-006870-f5w6fw6q 66 12 mortality mortality NN cord-006870-f5w6fw6q 66 13 in in IN cord-006870-f5w6fw6q 66 14 acute acute JJ cord-006870-f5w6fw6q 66 15 anoxic anoxic JJ cord-006870-f5w6fw6q 66 16 brain brain NN cord-006870-f5w6fw6q 66 17 injury injury NN cord-006870-f5w6fw6q 67 1 We -PRON- PRP cord-006870-f5w6fw6q 67 2 utilized utilize VBD cord-006870-f5w6fw6q 67 3 healthcare healthcare NN cord-006870-f5w6fw6q 67 4 cost cost NN cord-006870-f5w6fw6q 67 5 and and CC cord-006870-f5w6fw6q 67 6 utilization utilization NN cord-006870-f5w6fw6q 67 7 project project NN cord-006870-f5w6fw6q 67 8 databases database NNS cord-006870-f5w6fw6q 67 9 ( ( -LRB- cord-006870-f5w6fw6q 67 10 Nationwide Nationwide NNP cord-006870-f5w6fw6q 67 11 Inpatient Inpatient NNP cord-006870-f5w6fw6q 67 12 Sample Sample NNP cord-006870-f5w6fw6q 67 13 and and CC cord-006870-f5w6fw6q 67 14 Kids Kids NNPS cord-006870-f5w6fw6q 67 15 ' ' POS cord-006870-f5w6fw6q 67 16 Inpatient Inpatient NNP cord-006870-f5w6fw6q 67 17 Database Database NNP cord-006870-f5w6fw6q 67 18 ) ) -RRB- cord-006870-f5w6fw6q 67 19 to to TO cord-006870-f5w6fw6q 67 20 obtain obtain VB cord-006870-f5w6fw6q 67 21 patients patient NNS cord-006870-f5w6fw6q 67 22 admitted admit VBN cord-006870-f5w6fw6q 67 23 with with IN cord-006870-f5w6fw6q 67 24 diagnosis diagnosis NN cord-006870-f5w6fw6q 67 25 of of IN cord-006870-f5w6fw6q 67 26 anoxic anoxic JJ cord-006870-f5w6fw6q 67 27 brain brain NN cord-006870-f5w6fw6q 67 28 injury injury NN cord-006870-f5w6fw6q 67 29 . . . cord-006870-f5w6fw6q 68 1 Patients patient NNS cord-006870-f5w6fw6q 68 2 with with IN cord-006870-f5w6fw6q 68 3 drug drug NN cord-006870-f5w6fw6q 68 4 intoxication intoxication NN cord-006870-f5w6fw6q 68 5 ( ( -LRB- cord-006870-f5w6fw6q 68 6 opioid opioid NN cord-006870-f5w6fw6q 68 7 , , , cord-006870-f5w6fw6q 68 8 alcohol alcohol NN cord-006870-f5w6fw6q 68 9 , , , cord-006870-f5w6fw6q 68 10 sedative sedative JJ cord-006870-f5w6fw6q 68 11 / / SYM cord-006870-f5w6fw6q 68 12 hypnotic hypnotic JJ cord-006870-f5w6fw6q 68 13 drugs drug NNS cord-006870-f5w6fw6q 68 14 ) ) -RRB- cord-006870-f5w6fw6q 68 15 were be VBD cord-006870-f5w6fw6q 68 16 identified identify VBN cord-006870-f5w6fw6q 68 17 . . . cord-006870-f5w6fw6q 69 1 Regression regression NN cord-006870-f5w6fw6q 69 2 analysis analysis NN cord-006870-f5w6fw6q 69 3 was be VBD cord-006870-f5w6fw6q 69 4 used use VBN cord-006870-f5w6fw6q 69 5 to to TO cord-006870-f5w6fw6q 69 6 assess assess VB cord-006870-f5w6fw6q 69 7 relationship relationship NN cord-006870-f5w6fw6q 69 8 between between IN cord-006870-f5w6fw6q 69 9 drug drug NN cord-006870-f5w6fw6q 69 10 intoxication intoxication NN cord-006870-f5w6fw6q 69 11 status status NN cord-006870-f5w6fw6q 69 12 to to IN cord-006870-f5w6fw6q 69 13 in in IN cord-006870-f5w6fw6q 69 14 - - HYPH cord-006870-f5w6fw6q 69 15 hospital hospital NN cord-006870-f5w6fw6q 69 16 mortality mortality NN cord-006870-f5w6fw6q 69 17 . . . cord-006870-f5w6fw6q 70 1 The the DT cord-006870-f5w6fw6q 70 2 regression regression NN cord-006870-f5w6fw6q 70 3 model model NN cord-006870-f5w6fw6q 70 4 was be VBD cord-006870-f5w6fw6q 70 5 adjusted adjust VBN cord-006870-f5w6fw6q 70 6 for for IN cord-006870-f5w6fw6q 70 7 age age NN cord-006870-f5w6fw6q 70 8 , , , cord-006870-f5w6fw6q 70 9 gender gender NN cord-006870-f5w6fw6q 70 10 , , , cord-006870-f5w6fw6q 70 11 chronic chronic JJ cord-006870-f5w6fw6q 70 12 medical medical JJ cord-006870-f5w6fw6q 70 13 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 70 14 , , , cord-006870-f5w6fw6q 70 15 presence presence NN cord-006870-f5w6fw6q 70 16 of of IN cord-006870-f5w6fw6q 70 17 cardiac cardiac JJ cord-006870-f5w6fw6q 70 18 arrest arrest NN cord-006870-f5w6fw6q 70 19 and and CC cord-006870-f5w6fw6q 70 20 hospital hospital NN cord-006870-f5w6fw6q 70 21 characteristics characteristic NNS cord-006870-f5w6fw6q 70 22 . . . cord-006870-f5w6fw6q 71 1 We -PRON- PRP cord-006870-f5w6fw6q 71 2 analyzed analyze VBD cord-006870-f5w6fw6q 71 3 a a DT cord-006870-f5w6fw6q 71 4 total total NN cord-006870-f5w6fw6q 71 5 of of IN cord-006870-f5w6fw6q 71 6 12,319 12,319 CD cord-006870-f5w6fw6q 71 7 patients patient NNS cord-006870-f5w6fw6q 71 8 with with IN cord-006870-f5w6fw6q 71 9 anoxic anoxic JJ cord-006870-f5w6fw6q 71 10 brain brain NN cord-006870-f5w6fw6q 71 11 injury injury NN cord-006870-f5w6fw6q 71 12 out out IN cord-006870-f5w6fw6q 71 13 of of IN cord-006870-f5w6fw6q 71 14 which which WDT cord-006870-f5w6fw6q 71 15 197 197 CD cord-006870-f5w6fw6q 71 16 ( ( -LRB- cord-006870-f5w6fw6q 71 17 1.6 1.6 CD cord-006870-f5w6fw6q 71 18 % % NN cord-006870-f5w6fw6q 71 19 ) ) -RRB- cord-006870-f5w6fw6q 71 20 had have VBD cord-006870-f5w6fw6q 71 21 drug drug NN cord-006870-f5w6fw6q 71 22 intoxication intoxication NN cord-006870-f5w6fw6q 71 23 and and CC cord-006870-f5w6fw6q 71 24 35 35 CD cord-006870-f5w6fw6q 71 25 % % NN cord-006870-f5w6fw6q 71 26 were be VBD cord-006870-f5w6fw6q 71 27 reported report VBN cord-006870-f5w6fw6q 71 28 to to TO cord-006870-f5w6fw6q 71 29 have have VB cord-006870-f5w6fw6q 71 30 cardiac cardiac JJ cord-006870-f5w6fw6q 71 31 arrest arrest NN cord-006870-f5w6fw6q 71 32 . . . cord-006870-f5w6fw6q 72 1 Median median JJ cord-006870-f5w6fw6q 72 2 age age NN cord-006870-f5w6fw6q 72 3 was be VBD cord-006870-f5w6fw6q 72 4 58 58 CD cord-006870-f5w6fw6q 72 5 years year NNS cord-006870-f5w6fw6q 72 6 and and CC cord-006870-f5w6fw6q 72 7 54 54 CD cord-006870-f5w6fw6q 72 8 % % NN cord-006870-f5w6fw6q 72 9 patients patient NNS cord-006870-f5w6fw6q 72 10 were be VBD cord-006870-f5w6fw6q 72 11 males male NNS cord-006870-f5w6fw6q 72 12 . . . cord-006870-f5w6fw6q 73 1 In in IN cord-006870-f5w6fw6q 73 2 - - HYPH cord-006870-f5w6fw6q 73 3 hospital hospital NN cord-006870-f5w6fw6q 73 4 mortality mortality NN cord-006870-f5w6fw6q 73 5 was be VBD cord-006870-f5w6fw6q 73 6 57 57 CD cord-006870-f5w6fw6q 73 7 % % NN cord-006870-f5w6fw6q 73 8 . . . cord-006870-f5w6fw6q 74 1 Among among IN cord-006870-f5w6fw6q 74 2 the the DT cord-006870-f5w6fw6q 74 3 survivors survivor NNS cord-006870-f5w6fw6q 74 4 , , , cord-006870-f5w6fw6q 74 5 20 20 CD cord-006870-f5w6fw6q 74 6 % % NN cord-006870-f5w6fw6q 74 7 underwent undergo VBD cord-006870-f5w6fw6q 74 8 feeding feed VBG cord-006870-f5w6fw6q 74 9 tube tube NN cord-006870-f5w6fw6q 74 10 placement placement NN cord-006870-f5w6fw6q 74 11 and and CC cord-006870-f5w6fw6q 74 12 15 15 CD cord-006870-f5w6fw6q 74 13 % % NN cord-006870-f5w6fw6q 74 14 had have VBD cord-006870-f5w6fw6q 74 15 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 74 16 . . . cord-006870-f5w6fw6q 75 1 Drug drug NN cord-006870-f5w6fw6q 75 2 intoxication intoxication NN cord-006870-f5w6fw6q 75 3 was be VBD cord-006870-f5w6fw6q 75 4 a a DT cord-006870-f5w6fw6q 75 5 significant significant JJ cord-006870-f5w6fw6q 75 6 positive positive JJ cord-006870-f5w6fw6q 75 7 predictor predictor NN cord-006870-f5w6fw6q 75 8 of of IN cord-006870-f5w6fw6q 75 9 inhospital inhospital JJ cord-006870-f5w6fw6q 75 10 mortality mortality NN cord-006870-f5w6fw6q 75 11 with with IN cord-006870-f5w6fw6q 75 12 adjusted adjust VBN cord-006870-f5w6fw6q 75 13 odds odd NNS cord-006870-f5w6fw6q 75 14 ratio ratio NN cord-006870-f5w6fw6q 75 15 1.5 1.5 CD cord-006870-f5w6fw6q 75 16 ( ( -LRB- cord-006870-f5w6fw6q 75 17 1.1 1.1 CD cord-006870-f5w6fw6q 75 18 -2.1 -2.1 CD cord-006870-f5w6fw6q 75 19 ) ) -RRB- cord-006870-f5w6fw6q 75 20 , , , cord-006870-f5w6fw6q 75 21 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 75 22 . . . cord-006870-f5w6fw6q 76 1 CNS CNS NNP cord-006870-f5w6fw6q 76 2 depressant depressant JJ cord-006870-f5w6fw6q 76 3 drug drug NN cord-006870-f5w6fw6q 76 4 intoxication intoxication NN cord-006870-f5w6fw6q 76 5 is be VBZ cord-006870-f5w6fw6q 76 6 associated associate VBN cord-006870-f5w6fw6q 76 7 with with IN cord-006870-f5w6fw6q 76 8 higher high JJR cord-006870-f5w6fw6q 76 9 in in IN cord-006870-f5w6fw6q 76 10 - - HYPH cord-006870-f5w6fw6q 76 11 hospital hospital NN cord-006870-f5w6fw6q 76 12 mortality mortality NN cord-006870-f5w6fw6q 76 13 in in IN cord-006870-f5w6fw6q 76 14 patients patient NNS cord-006870-f5w6fw6q 76 15 with with IN cord-006870-f5w6fw6q 76 16 acute acute JJ cord-006870-f5w6fw6q 76 17 anoxic anoxic JJ cord-006870-f5w6fw6q 76 18 brain brain NN cord-006870-f5w6fw6q 76 19 injury injury NN cord-006870-f5w6fw6q 76 20 . . . cord-006870-f5w6fw6q 77 1 Cardiac cardiac JJ cord-006870-f5w6fw6q 77 2 arrest arrest NN cord-006870-f5w6fw6q 77 3 affects affect VBZ cord-006870-f5w6fw6q 77 4 approximately approximately RB cord-006870-f5w6fw6q 77 5 600,000 600,000 CD cord-006870-f5w6fw6q 77 6 individuals individual NNS cord-006870-f5w6fw6q 77 7 every every DT cord-006870-f5w6fw6q 77 8 year year NN cord-006870-f5w6fw6q 77 9 and and CC cord-006870-f5w6fw6q 77 10 is be VBZ cord-006870-f5w6fw6q 77 11 the the DT cord-006870-f5w6fw6q 77 12 third third JJ cord-006870-f5w6fw6q 77 13 most most RBS cord-006870-f5w6fw6q 77 14 common common JJ cord-006870-f5w6fw6q 77 15 cause cause NN cord-006870-f5w6fw6q 77 16 of of IN cord-006870-f5w6fw6q 77 17 mortality mortality NN cord-006870-f5w6fw6q 77 18 in in IN cord-006870-f5w6fw6q 77 19 the the DT cord-006870-f5w6fw6q 77 20 US US NNP cord-006870-f5w6fw6q 77 21 . . . cord-006870-f5w6fw6q 78 1 Currently currently RB cord-006870-f5w6fw6q 78 2 , , , cord-006870-f5w6fw6q 78 3 there there EX cord-006870-f5w6fw6q 78 4 is be VBZ cord-006870-f5w6fw6q 78 5 no no DT cord-006870-f5w6fw6q 78 6 way way NN cord-006870-f5w6fw6q 78 7 of of IN cord-006870-f5w6fw6q 78 8 reliably reliably RB cord-006870-f5w6fw6q 78 9 risk risk VBP cord-006870-f5w6fw6q 78 10 stratifying stratify VBG cord-006870-f5w6fw6q 78 11 survivors survivor NNS cord-006870-f5w6fw6q 78 12 of of IN cord-006870-f5w6fw6q 78 13 cardiac cardiac JJ cord-006870-f5w6fw6q 78 14 arrest arrest NN cord-006870-f5w6fw6q 78 15 . . . cord-006870-f5w6fw6q 79 1 Identifying identify VBG cord-006870-f5w6fw6q 79 2 early early JJ cord-006870-f5w6fw6q 79 3 predictors predictor NNS cord-006870-f5w6fw6q 79 4 of of IN cord-006870-f5w6fw6q 79 5 outcome outcome NN cord-006870-f5w6fw6q 79 6 is be VBZ cord-006870-f5w6fw6q 79 7 vital vital JJ cord-006870-f5w6fw6q 79 8 for for IN cord-006870-f5w6fw6q 79 9 triaging triage VBG cord-006870-f5w6fw6q 79 10 and and CC cord-006870-f5w6fw6q 79 11 clinical clinical JJ cord-006870-f5w6fw6q 79 12 trial trial NN cord-006870-f5w6fw6q 79 13 enrollment enrollment NN cord-006870-f5w6fw6q 79 14 . . . cord-006870-f5w6fw6q 80 1 We -PRON- PRP cord-006870-f5w6fw6q 80 2 proposed propose VBD cord-006870-f5w6fw6q 80 3 to to TO cord-006870-f5w6fw6q 80 4 identify identify VB cord-006870-f5w6fw6q 80 5 key key JJ cord-006870-f5w6fw6q 80 6 clinical clinical JJ cord-006870-f5w6fw6q 80 7 and and CC cord-006870-f5w6fw6q 80 8 laboratory laboratory NN cord-006870-f5w6fw6q 80 9 parameters parameter NNS cord-006870-f5w6fw6q 80 10 that that WDT cord-006870-f5w6fw6q 80 11 can can MD cord-006870-f5w6fw6q 80 12 reliably reliably RB cord-006870-f5w6fw6q 80 13 predict predict VB cord-006870-f5w6fw6q 80 14 long long JJ cord-006870-f5w6fw6q 80 15 - - HYPH cord-006870-f5w6fw6q 80 16 term term NN cord-006870-f5w6fw6q 80 17 outcomes outcome NNS cord-006870-f5w6fw6q 80 18 among among IN cord-006870-f5w6fw6q 80 19 comatose comatose JJ cord-006870-f5w6fw6q 80 20 survivors survivor NNS cord-006870-f5w6fw6q 80 21 of of IN cord-006870-f5w6fw6q 80 22 cardiac cardiac JJ cord-006870-f5w6fw6q 80 23 arrest arrest NN cord-006870-f5w6fw6q 80 24 . . . cord-006870-f5w6fw6q 81 1 This this DT cord-006870-f5w6fw6q 81 2 was be VBD cord-006870-f5w6fw6q 81 3 a a DT cord-006870-f5w6fw6q 81 4 retrospective retrospective JJ cord-006870-f5w6fw6q 81 5 chart chart NN cord-006870-f5w6fw6q 81 6 review review NN cord-006870-f5w6fw6q 81 7 of of IN cord-006870-f5w6fw6q 81 8 comatose comatose JJ cord-006870-f5w6fw6q 81 9 survivors survivor NNS cord-006870-f5w6fw6q 81 10 of of IN cord-006870-f5w6fw6q 81 11 cardiac cardiac JJ cord-006870-f5w6fw6q 81 12 arrest arrest NN cord-006870-f5w6fw6q 81 13 . . . cord-006870-f5w6fw6q 82 1 We -PRON- PRP cord-006870-f5w6fw6q 82 2 gathered gather VBD cord-006870-f5w6fw6q 82 3 data datum NNS cord-006870-f5w6fw6q 82 4 regarding regard VBG cord-006870-f5w6fw6q 82 5 several several JJ cord-006870-f5w6fw6q 82 6 clinical clinical JJ cord-006870-f5w6fw6q 82 7 ( ( -LRB- cord-006870-f5w6fw6q 82 8 age age NN cord-006870-f5w6fw6q 82 9 , , , cord-006870-f5w6fw6q 82 10 pre pre VBN cord-006870-f5w6fw6q 82 11 - - JJ cord-006870-f5w6fw6q 82 12 arrest arrest VB cord-006870-f5w6fw6q 82 13 mRS mRS NNP cord-006870-f5w6fw6q 82 14 , , , cord-006870-f5w6fw6q 82 15 GCS GCS NNP cord-006870-f5w6fw6q 82 16 on on IN cord-006870-f5w6fw6q 82 17 admission admission NN cord-006870-f5w6fw6q 82 18 , , , cord-006870-f5w6fw6q 82 19 24 24 CD cord-006870-f5w6fw6q 82 20 and and CC cord-006870-f5w6fw6q 82 21 48 48 CD cord-006870-f5w6fw6q 82 22 hours hour NNS cord-006870-f5w6fw6q 82 23 , , , cord-006870-f5w6fw6q 82 24 presence presence NN cord-006870-f5w6fw6q 82 25 / / SYM cord-006870-f5w6fw6q 82 26 absence absence NN cord-006870-f5w6fw6q 82 27 of of IN cord-006870-f5w6fw6q 82 28 shock shock NN cord-006870-f5w6fw6q 82 29 and and CC cord-006870-f5w6fw6q 82 30 respiratory respiratory JJ cord-006870-f5w6fw6q 82 31 failure failure NN cord-006870-f5w6fw6q 82 32 ) ) -RRB- cord-006870-f5w6fw6q 82 33 and and CC cord-006870-f5w6fw6q 82 34 laboratory laboratory NN cord-006870-f5w6fw6q 82 35 parameters parameter NNS cord-006870-f5w6fw6q 82 36 ( ( -LRB- cord-006870-f5w6fw6q 82 37 troponins troponin NNS cord-006870-f5w6fw6q 82 38 , , , cord-006870-f5w6fw6q 82 39 lactate lactate NN cord-006870-f5w6fw6q 82 40 , , , cord-006870-f5w6fw6q 82 41 creatinine creatinine NN cord-006870-f5w6fw6q 82 42 , , , cord-006870-f5w6fw6q 82 43 and and CC cord-006870-f5w6fw6q 82 44 ALT ALT NNP cord-006870-f5w6fw6q 82 45 at at IN cord-006870-f5w6fw6q 82 46 admission admission NN cord-006870-f5w6fw6q 82 47 , , , cord-006870-f5w6fw6q 82 48 and and CC cord-006870-f5w6fw6q 82 49 peak peak NN cord-006870-f5w6fw6q 82 50 values value NNS cord-006870-f5w6fw6q 82 51 within within IN cord-006870-f5w6fw6q 82 52 the the DT cord-006870-f5w6fw6q 82 53 first first JJ cord-006870-f5w6fw6q 82 54 24 24 CD cord-006870-f5w6fw6q 82 55 and and CC cord-006870-f5w6fw6q 82 56 48 48 CD cord-006870-f5w6fw6q 82 57 hours hour NNS cord-006870-f5w6fw6q 82 58 ) ) -RRB- cord-006870-f5w6fw6q 82 59 as as RB cord-006870-f5w6fw6q 82 60 well well RB cord-006870-f5w6fw6q 82 61 as as IN cord-006870-f5w6fw6q 82 62 characteristics characteristic NNS cord-006870-f5w6fw6q 82 63 of of IN cord-006870-f5w6fw6q 82 64 the the DT cord-006870-f5w6fw6q 82 65 cardiac cardiac JJ cord-006870-f5w6fw6q 82 66 arrest arrest NN cord-006870-f5w6fw6q 82 67 ( ( -LRB- cord-006870-f5w6fw6q 82 68 duration duration NN cord-006870-f5w6fw6q 82 69 , , , cord-006870-f5w6fw6q 82 70 arrest arrest NN cord-006870-f5w6fw6q 82 71 rhythm rhythm NN cord-006870-f5w6fw6q 82 72 , , , cord-006870-f5w6fw6q 82 73 location location NN cord-006870-f5w6fw6q 82 74 , , , cord-006870-f5w6fw6q 82 75 and and CC cord-006870-f5w6fw6q 82 76 bystander bystander NN cord-006870-f5w6fw6q 82 77 CPR CPR NNP cord-006870-f5w6fw6q 82 78 ) ) -RRB- cord-006870-f5w6fw6q 82 79 . . . cord-006870-f5w6fw6q 83 1 We -PRON- PRP cord-006870-f5w6fw6q 83 2 used use VBD cord-006870-f5w6fw6q 83 3 a a DT cord-006870-f5w6fw6q 83 4 dichotomized dichotomize VBN cord-006870-f5w6fw6q 83 5 GOS GOS NNP cord-006870-f5w6fw6q 83 6 ( ( -LRB- cord-006870-f5w6fw6q 83 7 1 1 CD cord-006870-f5w6fw6q 83 8 - - SYM cord-006870-f5w6fw6q 83 9 3 3 CD cord-006870-f5w6fw6q 83 10 vs vs IN cord-006870-f5w6fw6q 83 11 4 4 CD cord-006870-f5w6fw6q 83 12 - - SYM cord-006870-f5w6fw6q 83 13 5 5 CD cord-006870-f5w6fw6q 83 14 ) ) -RRB- cord-006870-f5w6fw6q 83 15 at at IN cord-006870-f5w6fw6q 83 16 6 6 CD cord-006870-f5w6fw6q 83 17 months month NNS cord-006870-f5w6fw6q 83 18 as as IN cord-006870-f5w6fw6q 83 19 the the DT cord-006870-f5w6fw6q 83 20 primary primary JJ cord-006870-f5w6fw6q 83 21 outcome outcome NN cord-006870-f5w6fw6q 83 22 . . . cord-006870-f5w6fw6q 84 1 We -PRON- PRP cord-006870-f5w6fw6q 84 2 performed perform VBD cord-006870-f5w6fw6q 84 3 univariate univariate JJ cord-006870-f5w6fw6q 84 4 and and CC cord-006870-f5w6fw6q 84 5 multivariable multivariable JJ cord-006870-f5w6fw6q 84 6 analysis analysis NN cord-006870-f5w6fw6q 84 7 to to TO cord-006870-f5w6fw6q 84 8 identify identify VB cord-006870-f5w6fw6q 84 9 predictors predictor NNS cord-006870-f5w6fw6q 84 10 of of IN cord-006870-f5w6fw6q 84 11 poor poor JJ cord-006870-f5w6fw6q 84 12 outcome outcome NN cord-006870-f5w6fw6q 84 13 . . . cord-006870-f5w6fw6q 85 1 A a DT cord-006870-f5w6fw6q 85 2 total total NN cord-006870-f5w6fw6q 85 3 of of IN cord-006870-f5w6fw6q 85 4 98 98 CD cord-006870-f5w6fw6q 85 5 patients patient NNS cord-006870-f5w6fw6q 85 6 were be VBD cord-006870-f5w6fw6q 85 7 enrolled enrol VBN cord-006870-f5w6fw6q 85 8 . . . cord-006870-f5w6fw6q 86 1 On on IN cord-006870-f5w6fw6q 86 2 univariate univariate JJ cord-006870-f5w6fw6q 86 3 analysis analysis NN cord-006870-f5w6fw6q 86 4 , , , cord-006870-f5w6fw6q 86 5 higher high JJR cord-006870-f5w6fw6q 86 6 age age NN cord-006870-f5w6fw6q 86 7 , , , cord-006870-f5w6fw6q 86 8 higher high JJR cord-006870-f5w6fw6q 86 9 pre pre JJ cord-006870-f5w6fw6q 86 10 - - JJ cord-006870-f5w6fw6q 86 11 arrest arrest JJ cord-006870-f5w6fw6q 86 12 mRS mrs XX cord-006870-f5w6fw6q 86 13 , , , cord-006870-f5w6fw6q 86 14 lower low JJR cord-006870-f5w6fw6q 86 15 GCS GCS NNP cord-006870-f5w6fw6q 86 16 at at IN cord-006870-f5w6fw6q 86 17 48 48 CD cord-006870-f5w6fw6q 86 18 hours hour NNS cord-006870-f5w6fw6q 86 19 , , , cord-006870-f5w6fw6q 86 20 non non JJ cord-006870-f5w6fw6q 86 21 VF VF NNP cord-006870-f5w6fw6q 86 22 / / SYM cord-006870-f5w6fw6q 86 23 VT VT NNP cord-006870-f5w6fw6q 86 24 arrest arrest NN cord-006870-f5w6fw6q 86 25 rhythm rhythm NN cord-006870-f5w6fw6q 86 26 , , , cord-006870-f5w6fw6q 86 27 in in IN cord-006870-f5w6fw6q 86 28 - - HYPH cord-006870-f5w6fw6q 86 29 hospital hospital NN cord-006870-f5w6fw6q 86 30 arrest arrest NN cord-006870-f5w6fw6q 86 31 location location NN cord-006870-f5w6fw6q 86 32 , , , cord-006870-f5w6fw6q 86 33 absence absence NN cord-006870-f5w6fw6q 86 34 of of IN cord-006870-f5w6fw6q 86 35 bystander bystander NN cord-006870-f5w6fw6q 86 36 CPR CPR NNP cord-006870-f5w6fw6q 86 37 , , , cord-006870-f5w6fw6q 86 38 and and CC cord-006870-f5w6fw6q 86 39 shock shock NN cord-006870-f5w6fw6q 86 40 were be VBD cord-006870-f5w6fw6q 86 41 statistically statistically RB cord-006870-f5w6fw6q 86 42 significant significant JJ cord-006870-f5w6fw6q 86 43 ( ( -LRB- cord-006870-f5w6fw6q 86 44 p p NN cord-006870-f5w6fw6q 86 45 < < XX cord-006870-f5w6fw6q 86 46 0.05 0.05 CD cord-006870-f5w6fw6q 86 47 ) ) -RRB- cord-006870-f5w6fw6q 86 48 for for IN cord-006870-f5w6fw6q 86 49 poor poor JJ cord-006870-f5w6fw6q 86 50 outcome outcome NN cord-006870-f5w6fw6q 86 51 . . . cord-006870-f5w6fw6q 87 1 In in IN cord-006870-f5w6fw6q 87 2 multivariable multivariable JJ cord-006870-f5w6fw6q 87 3 analysis analysis NN cord-006870-f5w6fw6q 87 4 , , , cord-006870-f5w6fw6q 87 5 only only RB cord-006870-f5w6fw6q 87 6 higher high JJR cord-006870-f5w6fw6q 87 7 prearrest prearrest NNP cord-006870-f5w6fw6q 87 8 mRS mRS , cord-006870-f5w6fw6q 87 9 and and CC cord-006870-f5w6fw6q 87 10 lower low JJR cord-006870-f5w6fw6q 87 11 GCS GCS NNP cord-006870-f5w6fw6q 87 12 at at IN cord-006870-f5w6fw6q 87 13 48 48 CD cord-006870-f5w6fw6q 87 14 hours hour NNS cord-006870-f5w6fw6q 87 15 were be VBD cord-006870-f5w6fw6q 87 16 independent independent JJ cord-006870-f5w6fw6q 87 17 predictors predictor NNS cord-006870-f5w6fw6q 87 18 of of IN cord-006870-f5w6fw6q 87 19 poor poor JJ cord-006870-f5w6fw6q 87 20 outcome outcome NN cord-006870-f5w6fw6q 87 21 ; ; : cord-006870-f5w6fw6q 87 22 no no DT cord-006870-f5w6fw6q 87 23 bystander bystander NN cord-006870-f5w6fw6q 87 24 CPR CPR NNP cord-006870-f5w6fw6q 87 25 demonstrated demonstrate VBD cord-006870-f5w6fw6q 87 26 a a DT cord-006870-f5w6fw6q 87 27 trend trend NN cord-006870-f5w6fw6q 87 28 for for IN cord-006870-f5w6fw6q 87 29 being be VBG cord-006870-f5w6fw6q 87 30 an an DT cord-006870-f5w6fw6q 87 31 independent independent JJ cord-006870-f5w6fw6q 87 32 predictor predictor NN cord-006870-f5w6fw6q 87 33 . . . cord-006870-f5w6fw6q 88 1 None none NN cord-006870-f5w6fw6q 88 2 of of IN cord-006870-f5w6fw6q 88 3 the the DT cord-006870-f5w6fw6q 88 4 early early JJ cord-006870-f5w6fw6q 88 5 laboratory laboratory NN cord-006870-f5w6fw6q 88 6 data datum NNS cord-006870-f5w6fw6q 88 7 achieved achieve VBD cord-006870-f5w6fw6q 88 8 statistical statistical JJ cord-006870-f5w6fw6q 88 9 significance significance NN cord-006870-f5w6fw6q 88 10 for for IN cord-006870-f5w6fw6q 88 11 predicting predict VBG cord-006870-f5w6fw6q 88 12 poor poor JJ cord-006870-f5w6fw6q 88 13 outcome outcome NN cord-006870-f5w6fw6q 88 14 . . . cord-006870-f5w6fw6q 89 1 We -PRON- PRP cord-006870-f5w6fw6q 89 2 identified identify VBD cord-006870-f5w6fw6q 89 3 several several JJ cord-006870-f5w6fw6q 89 4 clinical clinical JJ cord-006870-f5w6fw6q 89 5 predictors predictor NNS cord-006870-f5w6fw6q 89 6 of of IN cord-006870-f5w6fw6q 89 7 poor poor JJ cord-006870-f5w6fw6q 89 8 outcome outcome NN cord-006870-f5w6fw6q 89 9 in in IN cord-006870-f5w6fw6q 89 10 our -PRON- PRP$ cord-006870-f5w6fw6q 89 11 small small JJ cord-006870-f5w6fw6q 89 12 cohort cohort NN cord-006870-f5w6fw6q 89 13 of of IN cord-006870-f5w6fw6q 89 14 comatose comatose JJ cord-006870-f5w6fw6q 89 15 survivors survivor NNS cord-006870-f5w6fw6q 89 16 of of IN cord-006870-f5w6fw6q 89 17 cardiac cardiac JJ cord-006870-f5w6fw6q 89 18 arrest arrest NN cord-006870-f5w6fw6q 89 19 . . . cord-006870-f5w6fw6q 90 1 The the DT cord-006870-f5w6fw6q 90 2 above above JJ cord-006870-f5w6fw6q 90 3 variables variable NNS cord-006870-f5w6fw6q 90 4 need need VBP cord-006870-f5w6fw6q 90 5 to to TO cord-006870-f5w6fw6q 90 6 be be VB cord-006870-f5w6fw6q 90 7 analyzed analyze VBN cord-006870-f5w6fw6q 90 8 among among IN cord-006870-f5w6fw6q 90 9 a a DT cord-006870-f5w6fw6q 90 10 larger large JJR cord-006870-f5w6fw6q 90 11 cohort cohort NN cord-006870-f5w6fw6q 90 12 that that WDT cord-006870-f5w6fw6q 90 13 includes include VBZ cord-006870-f5w6fw6q 90 14 all all DT cord-006870-f5w6fw6q 90 15 survivors survivor NNS cord-006870-f5w6fw6q 90 16 of of IN cord-006870-f5w6fw6q 90 17 cardiac cardiac JJ cord-006870-f5w6fw6q 90 18 arrest arrest NN cord-006870-f5w6fw6q 90 19 in in IN cord-006870-f5w6fw6q 90 20 order order NN cord-006870-f5w6fw6q 90 21 to to TO cord-006870-f5w6fw6q 90 22 develop develop VB cord-006870-f5w6fw6q 90 23 an an DT cord-006870-f5w6fw6q 90 24 injury injury NN cord-006870-f5w6fw6q 90 25 severity severity NN cord-006870-f5w6fw6q 90 26 score score NN cord-006870-f5w6fw6q 90 27 that that WDT cord-006870-f5w6fw6q 90 28 can can MD cord-006870-f5w6fw6q 90 29 help help VB cord-006870-f5w6fw6q 90 30 risk risk NN cord-006870-f5w6fw6q 90 31 stratify stratify VB cord-006870-f5w6fw6q 90 32 cardiac cardiac JJ cord-006870-f5w6fw6q 90 33 arrest arrest NN cord-006870-f5w6fw6q 90 34 survivors survivor NNS cord-006870-f5w6fw6q 90 35 . . . cord-006870-f5w6fw6q 91 1 After after IN cord-006870-f5w6fw6q 91 2 cardiac cardiac JJ cord-006870-f5w6fw6q 91 3 arrest arrest NN cord-006870-f5w6fw6q 91 4 , , , cord-006870-f5w6fw6q 91 5 somatosensory somatosensory NN cord-006870-f5w6fw6q 91 6 evoked evoke VBN cord-006870-f5w6fw6q 91 7 potentials potential NNS cord-006870-f5w6fw6q 91 8 ( ( -LRB- cord-006870-f5w6fw6q 91 9 SSEPs SSEPs NNP cord-006870-f5w6fw6q 91 10 ) ) -RRB- cord-006870-f5w6fw6q 91 11 , , , cord-006870-f5w6fw6q 91 12 EEG EEG NNP cord-006870-f5w6fw6q 91 13 characteristics characteristic NNS cord-006870-f5w6fw6q 91 14 , , , cord-006870-f5w6fw6q 91 15 and and CC cord-006870-f5w6fw6q 91 16 MRI MRI NNP cord-006870-f5w6fw6q 91 17 are be VBP cord-006870-f5w6fw6q 91 18 routinely routinely RB cord-006870-f5w6fw6q 91 19 used use VBN cord-006870-f5w6fw6q 91 20 to to TO cord-006870-f5w6fw6q 91 21 evaluate evaluate VB cord-006870-f5w6fw6q 91 22 comatose comatose JJ cord-006870-f5w6fw6q 91 23 patients patient NNS cord-006870-f5w6fw6q 91 24 . . . cord-006870-f5w6fw6q 92 1 The the DT cord-006870-f5w6fw6q 92 2 relationship relationship NN cord-006870-f5w6fw6q 92 3 between between IN cord-006870-f5w6fw6q 92 4 structural structural JJ cord-006870-f5w6fw6q 92 5 hypoxic hypoxic JJ cord-006870-f5w6fw6q 92 6 injury injury NN cord-006870-f5w6fw6q 92 7 , , , cord-006870-f5w6fw6q 92 8 absent absent JJ cord-006870-f5w6fw6q 92 9 cortical cortical JJ cord-006870-f5w6fw6q 92 10 potentials potential NNS cord-006870-f5w6fw6q 92 11 and and CC cord-006870-f5w6fw6q 92 12 the the DT cord-006870-f5w6fw6q 92 13 generation generation NN cord-006870-f5w6fw6q 92 14 of of IN cord-006870-f5w6fw6q 92 15 background background NN cord-006870-f5w6fw6q 92 16 reactivity reactivity NN cord-006870-f5w6fw6q 92 17 or or CC cord-006870-f5w6fw6q 92 18 epileptogenic epileptogenic JJ cord-006870-f5w6fw6q 92 19 potentials potential NNS cord-006870-f5w6fw6q 92 20 is be VBZ cord-006870-f5w6fw6q 92 21 unclear unclear JJ cord-006870-f5w6fw6q 92 22 . . . cord-006870-f5w6fw6q 93 1 Here here RB cord-006870-f5w6fw6q 93 2 we -PRON- PRP cord-006870-f5w6fw6q 93 3 evaluate evaluate VBP cord-006870-f5w6fw6q 93 4 a a DT cord-006870-f5w6fw6q 93 5 consecutive consecutive JJ cord-006870-f5w6fw6q 93 6 series series NN cord-006870-f5w6fw6q 93 7 of of IN cord-006870-f5w6fw6q 93 8 patients patient NNS cord-006870-f5w6fw6q 93 9 with with IN cord-006870-f5w6fw6q 93 10 cardiac cardiac JJ cord-006870-f5w6fw6q 93 11 arrest arrest NN cord-006870-f5w6fw6q 93 12 that that WDT cord-006870-f5w6fw6q 93 13 were be VBD cord-006870-f5w6fw6q 93 14 studied study VBN cord-006870-f5w6fw6q 93 15 with with IN cord-006870-f5w6fw6q 93 16 SSEPs ssep NNS cord-006870-f5w6fw6q 93 17 and and CC cord-006870-f5w6fw6q 93 18 evaluate evaluate VB cord-006870-f5w6fw6q 93 19 clinical clinical JJ cord-006870-f5w6fw6q 93 20 , , , cord-006870-f5w6fw6q 93 21 EEG EEG NNP cord-006870-f5w6fw6q 93 22 , , , cord-006870-f5w6fw6q 93 23 and and CC cord-006870-f5w6fw6q 93 24 MRI MRI NNP cord-006870-f5w6fw6q 93 25 measures measure NNS cord-006870-f5w6fw6q 93 26 to to TO cord-006870-f5w6fw6q 93 27 study study VB cord-006870-f5w6fw6q 93 28 the the DT cord-006870-f5w6fw6q 93 29 dissociation dissociation NN cord-006870-f5w6fw6q 93 30 between between IN cord-006870-f5w6fw6q 93 31 hypoxia hypoxia NN cord-006870-f5w6fw6q 93 32 - - HYPH cord-006870-f5w6fw6q 93 33 induced induce VBN cord-006870-f5w6fw6q 93 34 thalamic thalamic JJ cord-006870-f5w6fw6q 93 35 disconnection disconnection NN cord-006870-f5w6fw6q 93 36 and and CC cord-006870-f5w6fw6q 93 37 spontaneous spontaneous JJ cord-006870-f5w6fw6q 93 38 cortical cortical JJ cord-006870-f5w6fw6q 93 39 activity activity NN cord-006870-f5w6fw6q 93 40 . . . cord-006870-f5w6fw6q 94 1 In in IN cord-006870-f5w6fw6q 94 2 this this DT cord-006870-f5w6fw6q 94 3 retrospective retrospective JJ cord-006870-f5w6fw6q 94 4 cohort cohort NN cord-006870-f5w6fw6q 94 5 study study NN cord-006870-f5w6fw6q 94 6 , , , cord-006870-f5w6fw6q 94 7 all all DT cord-006870-f5w6fw6q 94 8 comatose comatose JJ cord-006870-f5w6fw6q 94 9 patients patient NNS cord-006870-f5w6fw6q 94 10 post post VBP cord-006870-f5w6fw6q 94 11 - - JJ cord-006870-f5w6fw6q 94 12 cardiac cardiac JJ cord-006870-f5w6fw6q 94 13 arrest arrest NN cord-006870-f5w6fw6q 94 14 who who WP cord-006870-f5w6fw6q 94 15 received receive VBD cord-006870-f5w6fw6q 94 16 SSEPs ssep NNS cord-006870-f5w6fw6q 94 17 were be VBD cord-006870-f5w6fw6q 94 18 identified identify VBN cord-006870-f5w6fw6q 94 19 and and CC cord-006870-f5w6fw6q 94 20 reports report NNS cord-006870-f5w6fw6q 94 21 were be VBD cord-006870-f5w6fw6q 94 22 reviewed review VBN cord-006870-f5w6fw6q 94 23 . . . cord-006870-f5w6fw6q 95 1 71 71 CD cord-006870-f5w6fw6q 95 2 patients patient NNS cord-006870-f5w6fw6q 95 3 were be VBD cord-006870-f5w6fw6q 95 4 found find VBN cord-006870-f5w6fw6q 95 5 ; ; : cord-006870-f5w6fw6q 95 6 one one CD cord-006870-f5w6fw6q 95 7 patient patient NN cord-006870-f5w6fw6q 95 8 with with IN cord-006870-f5w6fw6q 95 9 a a DT cord-006870-f5w6fw6q 95 10 high high JJ cord-006870-f5w6fw6q 95 11 cervical cervical JJ cord-006870-f5w6fw6q 95 12 cord cord NN cord-006870-f5w6fw6q 95 13 injury injury NN cord-006870-f5w6fw6q 95 14 was be VBD cord-006870-f5w6fw6q 95 15 excluded exclude VBN cord-006870-f5w6fw6q 95 16 . . . cord-006870-f5w6fw6q 96 1 We -PRON- PRP cord-006870-f5w6fw6q 96 2 recorded record VBD cord-006870-f5w6fw6q 96 3 presence presence NN cord-006870-f5w6fw6q 96 4 of of IN cord-006870-f5w6fw6q 96 5 cortical cortical JJ cord-006870-f5w6fw6q 96 6 ( ( -LRB- cord-006870-f5w6fw6q 96 7 N20 N20 NNP cord-006870-f5w6fw6q 96 8 ) ) -RRB- cord-006870-f5w6fw6q 96 9 and and CC cord-006870-f5w6fw6q 96 10 subcortical subcortical JJ cord-006870-f5w6fw6q 96 11 evoked evoke VBN cord-006870-f5w6fw6q 96 12 responses response NNS cord-006870-f5w6fw6q 96 13 ( ( -LRB- cord-006870-f5w6fw6q 96 14 P14 P14 NNP cord-006870-f5w6fw6q 96 15 ) ) -RRB- cord-006870-f5w6fw6q 96 16 , , , cord-006870-f5w6fw6q 96 17 whenever whenever WRB cord-006870-f5w6fw6q 96 18 available available JJ cord-006870-f5w6fw6q 96 19 . . . cord-006870-f5w6fw6q 97 1 Based base VBN cord-006870-f5w6fw6q 97 2 on on IN cord-006870-f5w6fw6q 97 3 the the DT cord-006870-f5w6fw6q 97 4 closest close JJS cord-006870-f5w6fw6q 97 5 available available JJ cord-006870-f5w6fw6q 97 6 EEG EEG NNP cord-006870-f5w6fw6q 97 7 ( ( -LRB- cord-006870-f5w6fw6q 97 8 maximum maximum JJ cord-006870-f5w6fw6q 97 9 2 2 CD cord-006870-f5w6fw6q 97 10 days day NNS cord-006870-f5w6fw6q 97 11 from from IN cord-006870-f5w6fw6q 97 12 SSEP SSEP NNS cord-006870-f5w6fw6q 97 13 recording record VBG cord-006870-f5w6fw6q 97 14 ) ) -RRB- cord-006870-f5w6fw6q 97 15 we -PRON- PRP cord-006870-f5w6fw6q 97 16 determined determine VBD cord-006870-f5w6fw6q 97 17 reactivity reactivity NN cord-006870-f5w6fw6q 97 18 , , , cord-006870-f5w6fw6q 97 19 background background NN cord-006870-f5w6fw6q 97 20 characteristics characteristic NNS cord-006870-f5w6fw6q 97 21 ( ( -LRB- cord-006870-f5w6fw6q 97 22 diffuse diffuse JJ cord-006870-f5w6fw6q 97 23 suppression suppression NN cord-006870-f5w6fw6q 97 24 or or CC cord-006870-f5w6fw6q 97 25 burst burst NN cord-006870-f5w6fw6q 97 26 - - HYPH cord-006870-f5w6fw6q 97 27 suppression suppression NN cord-006870-f5w6fw6q 97 28 versus versus IN cord-006870-f5w6fw6q 97 29 all all DT cord-006870-f5w6fw6q 97 30 other other JJ cord-006870-f5w6fw6q 97 31 backgrounds background NNS cord-006870-f5w6fw6q 97 32 ) ) -RRB- cord-006870-f5w6fw6q 97 33 , , , cord-006870-f5w6fw6q 97 34 and and CC cord-006870-f5w6fw6q 97 35 presence presence NN cord-006870-f5w6fw6q 97 36 of of IN cord-006870-f5w6fw6q 97 37 generalized generalized JJ cord-006870-f5w6fw6q 97 38 periodic periodic JJ cord-006870-f5w6fw6q 97 39 discharges discharge NNS cord-006870-f5w6fw6q 97 40 ( ( -LRB- cord-006870-f5w6fw6q 97 41 GPDs gpd NNS cord-006870-f5w6fw6q 97 42 ) ) -RRB- cord-006870-f5w6fw6q 97 43 or or CC cord-006870-f5w6fw6q 97 44 seizures seizure NNS cord-006870-f5w6fw6q 97 45 . . . cord-006870-f5w6fw6q 98 1 Diffusion diffusion NN cord-006870-f5w6fw6q 98 2 weighted weight VBN cord-006870-f5w6fw6q 98 3 or or CC cord-006870-f5w6fw6q 98 4 T2 T2 NNP cord-006870-f5w6fw6q 98 5 FLAIR flair NN cord-006870-f5w6fw6q 98 6 abnormalities abnormality NNS cord-006870-f5w6fw6q 98 7 in in IN cord-006870-f5w6fw6q 98 8 the the DT cord-006870-f5w6fw6q 98 9 thalamus thalamus NN cord-006870-f5w6fw6q 98 10 were be VBD cord-006870-f5w6fw6q 98 11 evaluated evaluate VBN cord-006870-f5w6fw6q 98 12 based base VBN cord-006870-f5w6fw6q 98 13 on on IN cord-006870-f5w6fw6q 98 14 available available JJ cord-006870-f5w6fw6q 98 15 MRIs mri NNS cord-006870-f5w6fw6q 98 16 . . . cord-006870-f5w6fw6q 99 1 Chi Chi NNP cord-006870-f5w6fw6q 99 2 - - HYPH cord-006870-f5w6fw6q 99 3 square square NNP cord-006870-f5w6fw6q 99 4 and and CC cord-006870-f5w6fw6q 99 5 Fisher Fisher NNP cord-006870-f5w6fw6q 99 6 's 's POS cord-006870-f5w6fw6q 99 7 exact exact JJ cord-006870-f5w6fw6q 99 8 test test NN cord-006870-f5w6fw6q 99 9 were be VBD cord-006870-f5w6fw6q 99 10 applied apply VBN cord-006870-f5w6fw6q 99 11 as as IN cord-006870-f5w6fw6q 99 12 applicable applicable JJ cord-006870-f5w6fw6q 99 13 . . . cord-006870-f5w6fw6q 100 1 Of of IN cord-006870-f5w6fw6q 100 2 70 70 CD cord-006870-f5w6fw6q 100 3 patients patient NNS cord-006870-f5w6fw6q 100 4 with with IN cord-006870-f5w6fw6q 100 5 SSEP SSEP NNS cord-006870-f5w6fw6q 100 6 , , , cord-006870-f5w6fw6q 100 7 33 33 CD cord-006870-f5w6fw6q 100 8 ( ( -LRB- cord-006870-f5w6fw6q 100 9 47 47 CD cord-006870-f5w6fw6q 100 10 % % NN cord-006870-f5w6fw6q 100 11 ) ) -RRB- cord-006870-f5w6fw6q 100 12 had have VBD cord-006870-f5w6fw6q 100 13 absent absent JJ cord-006870-f5w6fw6q 100 14 N20s n20s NN cord-006870-f5w6fw6q 100 15 , , , cord-006870-f5w6fw6q 100 16 and and CC cord-006870-f5w6fw6q 100 17 29 29 CD cord-006870-f5w6fw6q 100 18 % % NN cord-006870-f5w6fw6q 100 19 of of IN cord-006870-f5w6fw6q 100 20 those those DT cord-006870-f5w6fw6q 100 21 ( ( -LRB- cord-006870-f5w6fw6q 100 22 n=9 n=9 NN cord-006870-f5w6fw6q 100 23 ) ) -RRB- cord-006870-f5w6fw6q 100 24 had have VBD cord-006870-f5w6fw6q 100 25 absent absent JJ cord-006870-f5w6fw6q 100 26 P14 P14 NNP cord-006870-f5w6fw6q 100 27 . . . cord-006870-f5w6fw6q 101 1 EEG EEG NNP cord-006870-f5w6fw6q 101 2 reactivity reactivity NN cord-006870-f5w6fw6q 101 3 was be VBD cord-006870-f5w6fw6q 101 4 possible possible JJ cord-006870-f5w6fw6q 101 5 , , , cord-006870-f5w6fw6q 101 6 albeit albeit IN cord-006870-f5w6fw6q 101 7 less less RBR cord-006870-f5w6fw6q 101 8 common common JJ cord-006870-f5w6fw6q 101 9 , , , cord-006870-f5w6fw6q 101 10 in in IN cord-006870-f5w6fw6q 101 11 patients patient NNS cord-006870-f5w6fw6q 101 12 with with IN cord-006870-f5w6fw6q 101 13 absent absent JJ cord-006870-f5w6fw6q 101 14 N20s n20s NN cord-006870-f5w6fw6q 102 1 ( ( -LRB- cord-006870-f5w6fw6q 102 2 10 10 CD cord-006870-f5w6fw6q 102 3 % % NN cord-006870-f5w6fw6q 102 4 vs vs IN cord-006870-f5w6fw6q 102 5 51 51 CD cord-006870-f5w6fw6q 102 6 % % NN cord-006870-f5w6fw6q 102 7 , , , cord-006870-f5w6fw6q 102 8 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 102 9 ) ) -RRB- cord-006870-f5w6fw6q 102 10 , , , cord-006870-f5w6fw6q 102 11 but but CC cord-006870-f5w6fw6q 102 12 none none NN cord-006870-f5w6fw6q 102 13 of of IN cord-006870-f5w6fw6q 102 14 the the DT cord-006870-f5w6fw6q 102 15 patients patient NNS cord-006870-f5w6fw6q 102 16 with with IN cord-006870-f5w6fw6q 102 17 absent absent JJ cord-006870-f5w6fw6q 102 18 P14s p14 NNS cord-006870-f5w6fw6q 102 19 had have VBD cord-006870-f5w6fw6q 102 20 a a DT cord-006870-f5w6fw6q 102 21 reactive reactive JJ cord-006870-f5w6fw6q 102 22 EEG EEG NNP cord-006870-f5w6fw6q 102 23 . . . cord-006870-f5w6fw6q 103 1 Those those DT cord-006870-f5w6fw6q 103 2 with with IN cord-006870-f5w6fw6q 103 3 absent absent JJ cord-006870-f5w6fw6q 103 4 N20s n20 NNS cord-006870-f5w6fw6q 103 5 were be VBD cord-006870-f5w6fw6q 103 6 more more RBR cord-006870-f5w6fw6q 103 7 likely likely JJ cord-006870-f5w6fw6q 103 8 to to TO cord-006870-f5w6fw6q 103 9 have have VB cord-006870-f5w6fw6q 103 10 diffusely diffusely RB cord-006870-f5w6fw6q 103 11 suppressed suppress VBN cord-006870-f5w6fw6q 103 12 or or CC cord-006870-f5w6fw6q 103 13 burst burst NN cord-006870-f5w6fw6q 103 14 - - HYPH cord-006870-f5w6fw6q 103 15 suppressed suppress VBN cord-006870-f5w6fw6q 103 16 background background NN cord-006870-f5w6fw6q 103 17 ( ( -LRB- cord-006870-f5w6fw6q 103 18 94 94 CD cord-006870-f5w6fw6q 103 19 % % NN cord-006870-f5w6fw6q 103 20 vs vs IN cord-006870-f5w6fw6q 103 21 51 51 CD cord-006870-f5w6fw6q 103 22 % % NN cord-006870-f5w6fw6q 103 23 , , , cord-006870-f5w6fw6q 103 24 p=0.03 p=0.03 NNP cord-006870-f5w6fw6q 103 25 ) ) -RRB- cord-006870-f5w6fw6q 103 26 and and CC cord-006870-f5w6fw6q 103 27 to to TO cord-006870-f5w6fw6q 103 28 have have VB cord-006870-f5w6fw6q 103 29 abnormal abnormal JJ cord-006870-f5w6fw6q 103 30 thalamic thalamic JJ cord-006870-f5w6fw6q 103 31 signal signal NN cord-006870-f5w6fw6q 103 32 on on IN cord-006870-f5w6fw6q 103 33 MRI MRI NNP cord-006870-f5w6fw6q 103 34 ( ( -LRB- cord-006870-f5w6fw6q 103 35 50 50 CD cord-006870-f5w6fw6q 103 36 % % NN cord-006870-f5w6fw6q 103 37 vs vs IN cord-006870-f5w6fw6q 103 38 12 12 CD cord-006870-f5w6fw6q 103 39 % % NN cord-006870-f5w6fw6q 103 40 , , , cord-006870-f5w6fw6q 103 41 p=0.008 p=0.008 NNP cord-006870-f5w6fw6q 103 42 ) ) -RRB- cord-006870-f5w6fw6q 103 43 . . . cord-006870-f5w6fw6q 104 1 GPDs gpd NNS cord-006870-f5w6fw6q 104 2 , , , cord-006870-f5w6fw6q 104 3 stimulus stimulus NN cord-006870-f5w6fw6q 104 4 - - HYPH cord-006870-f5w6fw6q 104 5 induced induce VBN cord-006870-f5w6fw6q 104 6 GPDs gpd NNS cord-006870-f5w6fw6q 104 7 , , , cord-006870-f5w6fw6q 104 8 and and CC cord-006870-f5w6fw6q 104 9 seizures seizure NNS cord-006870-f5w6fw6q 104 10 were be VBD cord-006870-f5w6fw6q 104 11 equally equally RB cord-006870-f5w6fw6q 104 12 common common JJ cord-006870-f5w6fw6q 104 13 in in IN cord-006870-f5w6fw6q 104 14 those those DT cord-006870-f5w6fw6q 104 15 with with IN cord-006870-f5w6fw6q 104 16 and and CC cord-006870-f5w6fw6q 104 17 without without IN cord-006870-f5w6fw6q 104 18 N20s n20s PRP cord-006870-f5w6fw6q 104 19 . . . cord-006870-f5w6fw6q 105 1 The the DT cord-006870-f5w6fw6q 105 2 integrity integrity NN cord-006870-f5w6fw6q 105 3 of of IN cord-006870-f5w6fw6q 105 4 the the DT cord-006870-f5w6fw6q 105 5 somatosensory somatosensory JJ cord-006870-f5w6fw6q 105 6 thalamo thalamo NN cord-006870-f5w6fw6q 105 7 - - HYPH cord-006870-f5w6fw6q 105 8 cortical cortical JJ cord-006870-f5w6fw6q 105 9 pathway pathway NN cord-006870-f5w6fw6q 105 10 does do VBZ cord-006870-f5w6fw6q 105 11 not not RB cord-006870-f5w6fw6q 105 12 appear appear VB cord-006870-f5w6fw6q 105 13 to to TO cord-006870-f5w6fw6q 105 14 be be VB cord-006870-f5w6fw6q 105 15 necessary necessary JJ cord-006870-f5w6fw6q 105 16 for for IN cord-006870-f5w6fw6q 105 17 presence presence NN cord-006870-f5w6fw6q 105 18 of of IN cord-006870-f5w6fw6q 105 19 reactivity reactivity NN cord-006870-f5w6fw6q 105 20 or or CC cord-006870-f5w6fw6q 105 21 generation generation NN cord-006870-f5w6fw6q 105 22 of of IN cord-006870-f5w6fw6q 105 23 periodic periodic JJ cord-006870-f5w6fw6q 105 24 epileptiform epileptiform NN cord-006870-f5w6fw6q 105 25 discharges discharge NNS cord-006870-f5w6fw6q 105 26 . . . cord-006870-f5w6fw6q 106 1 All all DT cord-006870-f5w6fw6q 106 2 families family NNS cord-006870-f5w6fw6q 106 3 of of IN cord-006870-f5w6fw6q 106 4 patients patient NNS cord-006870-f5w6fw6q 106 5 who who WP cord-006870-f5w6fw6q 106 6 have have VBP cord-006870-f5w6fw6q 106 7 become become VBN cord-006870-f5w6fw6q 106 8 brain brain NN cord-006870-f5w6fw6q 106 9 dead dead JJ cord-006870-f5w6fw6q 106 10 ( ( -LRB- cord-006870-f5w6fw6q 106 11 BD BD NNP cord-006870-f5w6fw6q 106 12 ) ) -RRB- cord-006870-f5w6fw6q 106 13 should should MD cord-006870-f5w6fw6q 106 14 be be VB cord-006870-f5w6fw6q 106 15 offered offer VBN cord-006870-f5w6fw6q 106 16 the the DT cord-006870-f5w6fw6q 106 17 choice choice NN cord-006870-f5w6fw6q 106 18 of of IN cord-006870-f5w6fw6q 106 19 donation donation NN cord-006870-f5w6fw6q 106 20 . . . cord-006870-f5w6fw6q 107 1 This this DT cord-006870-f5w6fw6q 107 2 does do VBZ cord-006870-f5w6fw6q 107 3 not not RB cord-006870-f5w6fw6q 107 4 always always RB cord-006870-f5w6fw6q 107 5 happen happen VB cord-006870-f5w6fw6q 107 6 and and CC cord-006870-f5w6fw6q 107 7 the the DT cord-006870-f5w6fw6q 107 8 factors factor NNS cord-006870-f5w6fw6q 107 9 that that WDT cord-006870-f5w6fw6q 107 10 lead lead VBP cord-006870-f5w6fw6q 107 11 to to IN cord-006870-f5w6fw6q 107 12 approaching approach VBG cord-006870-f5w6fw6q 107 13 them -PRON- PRP cord-006870-f5w6fw6q 107 14 or or CC cord-006870-f5w6fw6q 107 15 not not RB cord-006870-f5w6fw6q 107 16 are be VBP cord-006870-f5w6fw6q 107 17 not not RB cord-006870-f5w6fw6q 107 18 known know VBN cord-006870-f5w6fw6q 107 19 . . . cord-006870-f5w6fw6q 108 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 108 2 objective objective NN cord-006870-f5w6fw6q 108 3 was be VBD cord-006870-f5w6fw6q 108 4 to to TO cord-006870-f5w6fw6q 108 5 evaluate evaluate VB cord-006870-f5w6fw6q 108 6 which which WDT cord-006870-f5w6fw6q 108 7 factors factor NNS cord-006870-f5w6fw6q 108 8 influence influence VBP cord-006870-f5w6fw6q 108 9 the the DT cord-006870-f5w6fw6q 108 10 donation donation NN cord-006870-f5w6fw6q 108 11 coordinators coordinator NNS cord-006870-f5w6fw6q 108 12 ( ( -LRB- cord-006870-f5w6fw6q 108 13 DC DC NNP cord-006870-f5w6fw6q 108 14 ) ) -RRB- cord-006870-f5w6fw6q 108 15 working work VBG cord-006870-f5w6fw6q 108 16 for for IN cord-006870-f5w6fw6q 108 17 an an DT cord-006870-f5w6fw6q 108 18 organ organ NN cord-006870-f5w6fw6q 108 19 procurement procurement NN cord-006870-f5w6fw6q 108 20 organization organization NN cord-006870-f5w6fw6q 108 21 approach approach VBP cord-006870-f5w6fw6q 108 22 families family NNS cord-006870-f5w6fw6q 108 23 after after IN cord-006870-f5w6fw6q 108 24 brain brain NN cord-006870-f5w6fw6q 108 25 death death NN cord-006870-f5w6fw6q 109 1 We -PRON- PRP cord-006870-f5w6fw6q 109 2 evaluated evaluate VBD cord-006870-f5w6fw6q 109 3 all all DT cord-006870-f5w6fw6q 109 4 declarations declaration NNS cord-006870-f5w6fw6q 109 5 in in IN cord-006870-f5w6fw6q 109 6 our -PRON- PRP$ cord-006870-f5w6fw6q 109 7 hospital hospital NN cord-006870-f5w6fw6q 109 8 's 's POS cord-006870-f5w6fw6q 109 9 BD BD NNP cord-006870-f5w6fw6q 109 10 registry registry NN cord-006870-f5w6fw6q 109 11 between between IN cord-006870-f5w6fw6q 109 12 January January NNP cord-006870-f5w6fw6q 109 13 2006 2006 CD cord-006870-f5w6fw6q 109 14 and and CC cord-006870-f5w6fw6q 109 15 June June NNP cord-006870-f5w6fw6q 109 16 2017 2017 CD cord-006870-f5w6fw6q 109 17 regarding regard VBG cord-006870-f5w6fw6q 109 18 consent consent NN cord-006870-f5w6fw6q 109 19 for for IN cord-006870-f5w6fw6q 109 20 donation donation NN cord-006870-f5w6fw6q 109 21 and and CC cord-006870-f5w6fw6q 109 22 cross cross NN cord-006870-f5w6fw6q 109 23 - - JJ cord-006870-f5w6fw6q 109 24 matched match VBN cord-006870-f5w6fw6q 109 25 the the DT cord-006870-f5w6fw6q 109 26 hospital hospital NN cord-006870-f5w6fw6q 109 27 electronic electronic JJ cord-006870-f5w6fw6q 109 28 medical medical JJ cord-006870-f5w6fw6q 109 29 records record NNS cord-006870-f5w6fw6q 109 30 with with IN cord-006870-f5w6fw6q 109 31 the the DT cord-006870-f5w6fw6q 109 32 records record NNS cord-006870-f5w6fw6q 109 33 of of IN cord-006870-f5w6fw6q 109 34 the the DT cord-006870-f5w6fw6q 109 35 local local JJ cord-006870-f5w6fw6q 109 36 organ organ NN cord-006870-f5w6fw6q 109 37 procurement procurement NN cord-006870-f5w6fw6q 109 38 organization organization NN cord-006870-f5w6fw6q 109 39 . . . cord-006870-f5w6fw6q 110 1 In in IN cord-006870-f5w6fw6q 110 2 order order NN cord-006870-f5w6fw6q 110 3 to to TO cord-006870-f5w6fw6q 110 4 refine refine VB cord-006870-f5w6fw6q 110 5 neurologic neurologic JJ cord-006870-f5w6fw6q 110 6 prognosis prognosis NN cord-006870-f5w6fw6q 110 7 in in IN cord-006870-f5w6fw6q 110 8 cardiac cardiac JJ cord-006870-f5w6fw6q 110 9 arrest arrest NN cord-006870-f5w6fw6q 110 10 patients patient NNS cord-006870-f5w6fw6q 110 11 we -PRON- PRP cord-006870-f5w6fw6q 110 12 sought seek VBD cord-006870-f5w6fw6q 110 13 to to TO cord-006870-f5w6fw6q 110 14 incorporate incorporate VB cord-006870-f5w6fw6q 110 15 heart heart NN cord-006870-f5w6fw6q 110 16 rate rate NN cord-006870-f5w6fw6q 110 17 variability variability NN cord-006870-f5w6fw6q 110 18 into into IN cord-006870-f5w6fw6q 110 19 a a DT cord-006870-f5w6fw6q 110 20 multimodal multimodal NN cord-006870-f5w6fw6q 110 21 prediction prediction NN cord-006870-f5w6fw6q 110 22 model model NN cord-006870-f5w6fw6q 110 23 . . . cord-006870-f5w6fw6q 111 1 Heart heart NN cord-006870-f5w6fw6q 111 2 rate rate NN cord-006870-f5w6fw6q 111 3 variability variability NN cord-006870-f5w6fw6q 111 4 has have VBZ cord-006870-f5w6fw6q 111 5 been be VBN cord-006870-f5w6fw6q 111 6 shown show VBN cord-006870-f5w6fw6q 111 7 in in IN cord-006870-f5w6fw6q 111 8 animal animal NN cord-006870-f5w6fw6q 111 9 studies study NNS cord-006870-f5w6fw6q 111 10 to to TO cord-006870-f5w6fw6q 111 11 be be VB cord-006870-f5w6fw6q 111 12 preserved preserve VBN cord-006870-f5w6fw6q 111 13 in in IN cord-006870-f5w6fw6q 111 14 survivors survivor NNS cord-006870-f5w6fw6q 111 15 of of IN cord-006870-f5w6fw6q 111 16 cardiac cardiac JJ cord-006870-f5w6fw6q 111 17 arrest arrest NN cord-006870-f5w6fw6q 111 18 . . . cord-006870-f5w6fw6q 112 1 In in IN cord-006870-f5w6fw6q 112 2 our -PRON- PRP$ cord-006870-f5w6fw6q 112 3 preliminary preliminary JJ cord-006870-f5w6fw6q 112 4 study study NN cord-006870-f5w6fw6q 112 5 , , , cord-006870-f5w6fw6q 112 6 we -PRON- PRP cord-006870-f5w6fw6q 112 7 retrospectively retrospectively RB cord-006870-f5w6fw6q 112 8 analyzed analyze VBD cord-006870-f5w6fw6q 112 9 patients patient NNS cord-006870-f5w6fw6q 112 10 admitted admit VBN cord-006870-f5w6fw6q 112 11 to to IN cord-006870-f5w6fw6q 112 12 the the DT cord-006870-f5w6fw6q 112 13 University University NNP cord-006870-f5w6fw6q 112 14 of of IN cord-006870-f5w6fw6q 112 15 Virginia Virginia NNP cord-006870-f5w6fw6q 112 16 who who WP cord-006870-f5w6fw6q 112 17 had have VBD cord-006870-f5w6fw6q 112 18 undergone undergo VBN cord-006870-f5w6fw6q 112 19 a a DT cord-006870-f5w6fw6q 112 20 cooling cool VBG cord-006870-f5w6fw6q 112 21 protocol protocol NN cord-006870-f5w6fw6q 112 22 following follow VBG cord-006870-f5w6fw6q 112 23 cardiac cardiac JJ cord-006870-f5w6fw6q 112 24 arrest arrest NN cord-006870-f5w6fw6q 112 25 . . . cord-006870-f5w6fw6q 113 1 Analysis analysis NN cord-006870-f5w6fw6q 113 2 of of IN cord-006870-f5w6fw6q 113 3 heart heart NN cord-006870-f5w6fw6q 113 4 rate rate NN cord-006870-f5w6fw6q 113 5 variability variability NN cord-006870-f5w6fw6q 113 6 for for IN cord-006870-f5w6fw6q 113 7 each each DT cord-006870-f5w6fw6q 113 8 patient patient NN cord-006870-f5w6fw6q 113 9 was be VBD cord-006870-f5w6fw6q 113 10 done do VBN cord-006870-f5w6fw6q 113 11 in in IN cord-006870-f5w6fw6q 113 12 the the DT cord-006870-f5w6fw6q 113 13 frequency frequency NN cord-006870-f5w6fw6q 113 14 domain domain NN cord-006870-f5w6fw6q 113 15 using use VBG cord-006870-f5w6fw6q 113 16 the the DT cord-006870-f5w6fw6q 113 17 fast fast JJ cord-006870-f5w6fw6q 113 18 Fourier Fourier NNP cord-006870-f5w6fw6q 113 19 spectral spectral NN cord-006870-f5w6fw6q 113 20 transform transform NN cord-006870-f5w6fw6q 113 21 with with IN cord-006870-f5w6fw6q 113 22 spectral spectral JJ cord-006870-f5w6fw6q 113 23 bands band NNS cord-006870-f5w6fw6q 113 24 at at IN cord-006870-f5w6fw6q 113 25 0.150 0.150 CD cord-006870-f5w6fw6q 113 26 - - HYPH cord-006870-f5w6fw6q 113 27 0.400 0.400 CD cord-006870-f5w6fw6q 113 28 Hz Hz NNP cord-006870-f5w6fw6q 113 29 for for IN cord-006870-f5w6fw6q 113 30 high high JJ cord-006870-f5w6fw6q 113 31 frequency frequency NN cord-006870-f5w6fw6q 113 32 ( ( -LRB- cord-006870-f5w6fw6q 113 33 HF HF NNP cord-006870-f5w6fw6q 113 34 ) ) -RRB- cord-006870-f5w6fw6q 113 35 and and CC cord-006870-f5w6fw6q 113 36 low low JJ cord-006870-f5w6fw6q 113 37 frequency frequency NN cord-006870-f5w6fw6q 113 38 ( ( -LRB- cord-006870-f5w6fw6q 113 39 LF lf NN cord-006870-f5w6fw6q 113 40 ) ) -RRB- cord-006870-f5w6fw6q 113 41 power power NN cord-006870-f5w6fw6q 113 42 within within IN cord-006870-f5w6fw6q 113 43 the the DT cord-006870-f5w6fw6q 113 44 frequency frequency NN cord-006870-f5w6fw6q 113 45 band band NN cord-006870-f5w6fw6q 113 46 0.040 0.040 CD cord-006870-f5w6fw6q 113 47 - - HYPH cord-006870-f5w6fw6q 113 48 0.150 0.150 CD cord-006870-f5w6fw6q 113 49 Hz Hz NNP cord-006870-f5w6fw6q 113 50 . . . cord-006870-f5w6fw6q 114 1 The the DT cord-006870-f5w6fw6q 114 2 unit unit NN cord-006870-f5w6fw6q 114 3 - - HYPH cord-006870-f5w6fw6q 114 4 less less JJR cord-006870-f5w6fw6q 114 5 LF LF NNP cord-006870-f5w6fw6q 114 6 / / SYM cord-006870-f5w6fw6q 114 7 HF HF NNP cord-006870-f5w6fw6q 114 8 ratio ratio NN cord-006870-f5w6fw6q 114 9 was be VBD cord-006870-f5w6fw6q 114 10 considered consider VBN cord-006870-f5w6fw6q 114 11 a a DT cord-006870-f5w6fw6q 114 12 measure measure NN cord-006870-f5w6fw6q 114 13 of of IN cord-006870-f5w6fw6q 114 14 balance balance NN cord-006870-f5w6fw6q 114 15 between between IN cord-006870-f5w6fw6q 114 16 sympathetic sympathetic JJ cord-006870-f5w6fw6q 114 17 and and CC cord-006870-f5w6fw6q 114 18 parasympathetic parasympathetic JJ cord-006870-f5w6fw6q 114 19 tone tone NN cord-006870-f5w6fw6q 114 20 . . . cord-006870-f5w6fw6q 115 1 Over over IN cord-006870-f5w6fw6q 115 2 a a DT cord-006870-f5w6fw6q 115 3 3-year 3-year CD cord-006870-f5w6fw6q 115 4 period period NN cord-006870-f5w6fw6q 115 5 , , , cord-006870-f5w6fw6q 115 6 a a DT cord-006870-f5w6fw6q 115 7 total total NN cord-006870-f5w6fw6q 115 8 of of IN cord-006870-f5w6fw6q 115 9 167 167 CD cord-006870-f5w6fw6q 115 10 patients patient NNS cord-006870-f5w6fw6q 115 11 were be VBD cord-006870-f5w6fw6q 115 12 cooled cool VBN cord-006870-f5w6fw6q 115 13 . . . cord-006870-f5w6fw6q 116 1 45 45 CD cord-006870-f5w6fw6q 116 2 patients patient NNS cord-006870-f5w6fw6q 116 3 ( ( -LRB- cord-006870-f5w6fw6q 116 4 27 27 CD cord-006870-f5w6fw6q 116 5 % % NN cord-006870-f5w6fw6q 116 6 ) ) -RRB- cord-006870-f5w6fw6q 116 7 had have VBD cord-006870-f5w6fw6q 116 8 cEEG cEEG VBN cord-006870-f5w6fw6q 116 9 , , , cord-006870-f5w6fw6q 116 10 13 13 CD cord-006870-f5w6fw6q 116 11 ( ( -LRB- cord-006870-f5w6fw6q 116 12 8 8 CD cord-006870-f5w6fw6q 116 13 % % NN cord-006870-f5w6fw6q 116 14 ) ) -RRB- cord-006870-f5w6fw6q 116 15 had have VBD cord-006870-f5w6fw6q 116 16 routine routine JJ cord-006870-f5w6fw6q 116 17 EEGs eeg NNS cord-006870-f5w6fw6q 116 18 and and CC cord-006870-f5w6fw6q 116 19 17(10 17(10 CD cord-006870-f5w6fw6q 116 20 % % NN cord-006870-f5w6fw6q 116 21 ) ) -RRB- cord-006870-f5w6fw6q 116 22 had have VBD cord-006870-f5w6fw6q 116 23 SSEPs ssep NNS cord-006870-f5w6fw6q 116 24 performed perform VBN cord-006870-f5w6fw6q 116 25 . . . cord-006870-f5w6fw6q 117 1 Numerous numerous JJ cord-006870-f5w6fw6q 117 2 patients patient NNS cord-006870-f5w6fw6q 117 3 ( ( -LRB- cord-006870-f5w6fw6q 117 4 42 42 CD cord-006870-f5w6fw6q 117 5 , , , cord-006870-f5w6fw6q 117 6 25 25 CD cord-006870-f5w6fw6q 117 7 % % NN cord-006870-f5w6fw6q 117 8 of of IN cord-006870-f5w6fw6q 117 9 all all DT cord-006870-f5w6fw6q 117 10 arrests arrest NNS cord-006870-f5w6fw6q 117 11 or or CC cord-006870-f5w6fw6q 117 12 72 72 CD cord-006870-f5w6fw6q 117 13 % % NN cord-006870-f5w6fw6q 117 14 of of IN cord-006870-f5w6fw6q 117 15 all all DT cord-006870-f5w6fw6q 117 16 EEGs eeg NNS cord-006870-f5w6fw6q 117 17 performed perform VBD cord-006870-f5w6fw6q 117 18 ) ) -RRB- cord-006870-f5w6fw6q 117 19 had have VBD cord-006870-f5w6fw6q 117 20 malignant malignant JJ cord-006870-f5w6fw6q 117 21 patterns pattern NNS cord-006870-f5w6fw6q 117 22 , , , cord-006870-f5w6fw6q 117 23 defined define VBN cord-006870-f5w6fw6q 117 24 as as IN cord-006870-f5w6fw6q 117 25 burst burst NN cord-006870-f5w6fw6q 117 26 suppression suppression NN cord-006870-f5w6fw6q 117 27 , , , cord-006870-f5w6fw6q 117 28 severe severe JJ cord-006870-f5w6fw6q 117 29 suppression suppression NN cord-006870-f5w6fw6q 117 30 , , , cord-006870-f5w6fw6q 117 31 or or CC cord-006870-f5w6fw6q 117 32 generalized generalize VBN cord-006870-f5w6fw6q 117 33 periodic periodic JJ cord-006870-f5w6fw6q 117 34 discharges discharge NNS cord-006870-f5w6fw6q 117 35 . . . cord-006870-f5w6fw6q 118 1 Of of IN cord-006870-f5w6fw6q 118 2 the the DT cord-006870-f5w6fw6q 118 3 17 17 CD cord-006870-f5w6fw6q 118 4 SSEPS SSEPS NNP cord-006870-f5w6fw6q 118 5 , , , cord-006870-f5w6fw6q 118 6 10 10 CD cord-006870-f5w6fw6q 118 7 had have VBD cord-006870-f5w6fw6q 118 8 an an DT cord-006870-f5w6fw6q 118 9 absent absent JJ cord-006870-f5w6fw6q 118 10 N20 n20 NN cord-006870-f5w6fw6q 118 11 ( ( -LRB- cord-006870-f5w6fw6q 118 12 none none NN cord-006870-f5w6fw6q 118 13 survived survive VBD cord-006870-f5w6fw6q 118 14 to to TO cord-006870-f5w6fw6q 118 15 discharge discharge VB cord-006870-f5w6fw6q 118 16 ) ) -RRB- cord-006870-f5w6fw6q 118 17 and and CC cord-006870-f5w6fw6q 118 18 7 7 CD cord-006870-f5w6fw6q 118 19 had have VBD cord-006870-f5w6fw6q 118 20 an an DT cord-006870-f5w6fw6q 118 21 N20 N20 NNP cord-006870-f5w6fw6q 118 22 that that WDT cord-006870-f5w6fw6q 118 23 was be VBD cord-006870-f5w6fw6q 118 24 present present JJ cord-006870-f5w6fw6q 118 25 ( ( -LRB- cord-006870-f5w6fw6q 118 26 3 3 CD cord-006870-f5w6fw6q 118 27 survived survive VBD cord-006870-f5w6fw6q 118 28 to to TO cord-006870-f5w6fw6q 118 29 discharge discharge VB cord-006870-f5w6fw6q 118 30 ) ) -RRB- cord-006870-f5w6fw6q 118 31 . . . cord-006870-f5w6fw6q 119 1 2 2 CD cord-006870-f5w6fw6q 119 2 patients patient NNS cord-006870-f5w6fw6q 119 3 with with IN cord-006870-f5w6fw6q 119 4 absent absent JJ cord-006870-f5w6fw6q 119 5 N20s n20s NN cord-006870-f5w6fw6q 119 6 and and CC cord-006870-f5w6fw6q 119 7 malignant malignant JJ cord-006870-f5w6fw6q 119 8 EEGs eeg NNS cord-006870-f5w6fw6q 119 9 had have VBD cord-006870-f5w6fw6q 119 10 lower low JJR cord-006870-f5w6fw6q 119 11 LF LF NNP cord-006870-f5w6fw6q 119 12 / / SYM cord-006870-f5w6fw6q 119 13 HF HF NNP cord-006870-f5w6fw6q 119 14 ratios ratio NNS cord-006870-f5w6fw6q 119 15 when when WRB cord-006870-f5w6fw6q 119 16 compared compare VBN cord-006870-f5w6fw6q 119 17 to to IN cord-006870-f5w6fw6q 119 18 2 2 CD cord-006870-f5w6fw6q 119 19 survivors survivor NNS cord-006870-f5w6fw6q 119 20 with with IN cord-006870-f5w6fw6q 119 21 present present JJ cord-006870-f5w6fw6q 119 22 N20s N20s . cord-006870-f5w6fw6q 120 1 ( ( -LRB- cord-006870-f5w6fw6q 120 2 0.78 0.78 CD cord-006870-f5w6fw6q 120 3 vs. vs. IN cord-006870-f5w6fw6q 120 4 1.46 1.46 CD cord-006870-f5w6fw6q 120 5 ) ) -RRB- cord-006870-f5w6fw6q 120 6 . . . cord-006870-f5w6fw6q 121 1 The the DT cord-006870-f5w6fw6q 121 2 trend trend NN cord-006870-f5w6fw6q 121 3 towards towards IN cord-006870-f5w6fw6q 121 4 parasympathetic parasympathetic JJ cord-006870-f5w6fw6q 121 5 dominance dominance NN cord-006870-f5w6fw6q 121 6 following follow VBG cord-006870-f5w6fw6q 121 7 a a DT cord-006870-f5w6fw6q 121 8 severe severe JJ cord-006870-f5w6fw6q 121 9 neurologic neurologic JJ cord-006870-f5w6fw6q 121 10 injury injury NN cord-006870-f5w6fw6q 121 11 and and CC cord-006870-f5w6fw6q 121 12 loss loss NN cord-006870-f5w6fw6q 121 13 of of IN cord-006870-f5w6fw6q 121 14 normal normal JJ cord-006870-f5w6fw6q 121 15 sympathetic sympathetic JJ cord-006870-f5w6fw6q 121 16 tone tone NN cord-006870-f5w6fw6q 121 17 in in IN cord-006870-f5w6fw6q 121 18 those those DT cord-006870-f5w6fw6q 121 19 patients patient NNS cord-006870-f5w6fw6q 121 20 with with IN cord-006870-f5w6fw6q 121 21 absent absent JJ cord-006870-f5w6fw6q 121 22 N20s n20s NN cord-006870-f5w6fw6q 121 23 and and CC cord-006870-f5w6fw6q 121 24 malignant malignant JJ cord-006870-f5w6fw6q 121 25 EEGs eeg NNS cord-006870-f5w6fw6q 121 26 and and CC cord-006870-f5w6fw6q 121 27 may may MD cord-006870-f5w6fw6q 121 28 serve serve VB cord-006870-f5w6fw6q 121 29 as as IN cord-006870-f5w6fw6q 121 30 an an DT cord-006870-f5w6fw6q 121 31 additional additional JJ cord-006870-f5w6fw6q 121 32 marker marker NN cord-006870-f5w6fw6q 121 33 of of IN cord-006870-f5w6fw6q 121 34 poor poor JJ cord-006870-f5w6fw6q 121 35 prognosis prognosis NN cord-006870-f5w6fw6q 121 36 following follow VBG cord-006870-f5w6fw6q 121 37 cardiac cardiac JJ cord-006870-f5w6fw6q 121 38 arrest arrest NN cord-006870-f5w6fw6q 121 39 . . . cord-006870-f5w6fw6q 122 1 Physicians physician NNS cord-006870-f5w6fw6q 122 2 often often RB cord-006870-f5w6fw6q 122 3 struggle struggle VBP cord-006870-f5w6fw6q 122 4 with with IN cord-006870-f5w6fw6q 122 5 the the DT cord-006870-f5w6fw6q 122 6 intricacies intricacy NNS cord-006870-f5w6fw6q 122 7 of of IN cord-006870-f5w6fw6q 122 8 brain brain NN cord-006870-f5w6fw6q 122 9 death death NN cord-006870-f5w6fw6q 122 10 determination determination NN cord-006870-f5w6fw6q 122 11 and and CC cord-006870-f5w6fw6q 122 12 communication communication NN cord-006870-f5w6fw6q 122 13 about about IN cord-006870-f5w6fw6q 122 14 end end NN cord-006870-f5w6fw6q 122 15 - - HYPH cord-006870-f5w6fw6q 122 16 of of IN cord-006870-f5w6fw6q 122 17 - - HYPH cord-006870-f5w6fw6q 122 18 life life NN cord-006870-f5w6fw6q 122 19 care care NN cord-006870-f5w6fw6q 122 20 . . . cord-006870-f5w6fw6q 123 1 In in IN cord-006870-f5w6fw6q 123 2 an an DT cord-006870-f5w6fw6q 123 3 effort effort NN cord-006870-f5w6fw6q 123 4 to to TO cord-006870-f5w6fw6q 123 5 remedy remedy VB cord-006870-f5w6fw6q 123 6 this this DT cord-006870-f5w6fw6q 123 7 situation situation NN cord-006870-f5w6fw6q 123 8 , , , cord-006870-f5w6fw6q 123 9 we -PRON- PRP cord-006870-f5w6fw6q 123 10 introduced introduce VBD cord-006870-f5w6fw6q 123 11 an an DT cord-006870-f5w6fw6q 123 12 educational educational JJ cord-006870-f5w6fw6q 123 13 initiative initiative NN cord-006870-f5w6fw6q 123 14 at at IN cord-006870-f5w6fw6q 123 15 our -PRON- PRP$ cord-006870-f5w6fw6q 123 16 medical medical JJ cord-006870-f5w6fw6q 123 17 school school NN cord-006870-f5w6fw6q 123 18 to to TO cord-006870-f5w6fw6q 123 19 improve improve VB cord-006870-f5w6fw6q 123 20 student student NN cord-006870-f5w6fw6q 123 21 comprehension comprehension NN cord-006870-f5w6fw6q 123 22 and and CC cord-006870-f5w6fw6q 123 23 comfort comfort NN cord-006870-f5w6fw6q 123 24 dealing deal VBG cord-006870-f5w6fw6q 123 25 with with IN cord-006870-f5w6fw6q 123 26 brain brain NN cord-006870-f5w6fw6q 123 27 death death NN cord-006870-f5w6fw6q 123 28 . . . cord-006870-f5w6fw6q 124 1 Beginning begin VBG cord-006870-f5w6fw6q 124 2 in in IN cord-006870-f5w6fw6q 124 3 July July NNP cord-006870-f5w6fw6q 124 4 2017 2017 CD cord-006870-f5w6fw6q 124 5 , , , cord-006870-f5w6fw6q 124 6 students student NNS cord-006870-f5w6fw6q 124 7 at at IN cord-006870-f5w6fw6q 124 8 our -PRON- PRP$ cord-006870-f5w6fw6q 124 9 medical medical JJ cord-006870-f5w6fw6q 124 10 school school NN cord-006870-f5w6fw6q 124 11 were be VBD cord-006870-f5w6fw6q 124 12 required require VBN cord-006870-f5w6fw6q 124 13 to to TO cord-006870-f5w6fw6q 124 14 attend attend VB cord-006870-f5w6fw6q 124 15 a a DT cord-006870-f5w6fw6q 124 16 90-minute 90-minute JJ cord-006870-f5w6fw6q 124 17 brain brain NN cord-006870-f5w6fw6q 124 18 death death NN cord-006870-f5w6fw6q 124 19 didactic didactic JJ cord-006870-f5w6fw6q 124 20 and and CC cord-006870-f5w6fw6q 124 21 simulation simulation NN cord-006870-f5w6fw6q 124 22 session session NN cord-006870-f5w6fw6q 124 23 during during IN cord-006870-f5w6fw6q 124 24 their -PRON- PRP$ cord-006870-f5w6fw6q 124 25 neurology neurology NN cord-006870-f5w6fw6q 124 26 clerkship clerkship NN cord-006870-f5w6fw6q 124 27 . . . cord-006870-f5w6fw6q 125 1 Students student NNS cord-006870-f5w6fw6q 125 2 completed complete VBD cord-006870-f5w6fw6q 125 3 a a DT cord-006870-f5w6fw6q 125 4 test test NN cord-006870-f5w6fw6q 125 5 immediately immediately RB cord-006870-f5w6fw6q 125 6 before before IN cord-006870-f5w6fw6q 125 7 and and CC cord-006870-f5w6fw6q 125 8 after after IN cord-006870-f5w6fw6q 125 9 participating participate VBG cord-006870-f5w6fw6q 125 10 in in IN cord-006870-f5w6fw6q 125 11 the the DT cord-006870-f5w6fw6q 125 12 initiative initiative NN cord-006870-f5w6fw6q 125 13 . . . cord-006870-f5w6fw6q 126 1 Of of IN cord-006870-f5w6fw6q 126 2 the the DT cord-006870-f5w6fw6q 126 3 145 145 CD cord-006870-f5w6fw6q 126 4 students student NNS cord-006870-f5w6fw6q 126 5 who who WP cord-006870-f5w6fw6q 126 6 participated participate VBD cord-006870-f5w6fw6q 126 7 in in IN cord-006870-f5w6fw6q 126 8 this this DT cord-006870-f5w6fw6q 126 9 educational educational JJ cord-006870-f5w6fw6q 126 10 initiative initiative NN cord-006870-f5w6fw6q 126 11 between between IN cord-006870-f5w6fw6q 126 12 July July NNP cord-006870-f5w6fw6q 126 13 2016 2016 CD cord-006870-f5w6fw6q 126 14 and and CC cord-006870-f5w6fw6q 126 15 June June NNP cord-006870-f5w6fw6q 126 16 2017 2017 CD cord-006870-f5w6fw6q 126 17 , , , cord-006870-f5w6fw6q 126 18 124 124 CD cord-006870-f5w6fw6q 126 19 ( ( -LRB- cord-006870-f5w6fw6q 126 20 86 86 CD cord-006870-f5w6fw6q 126 21 % % NN cord-006870-f5w6fw6q 126 22 ) ) -RRB- cord-006870-f5w6fw6q 126 23 consented consent VBD cord-006870-f5w6fw6q 126 24 to to TO cord-006870-f5w6fw6q 126 25 have have VB cord-006870-f5w6fw6q 126 26 their -PRON- PRP$ cord-006870-f5w6fw6q 126 27 data datum NNS cord-006870-f5w6fw6q 126 28 used use VBN cord-006870-f5w6fw6q 126 29 for for IN cord-006870-f5w6fw6q 126 30 research research NN cord-006870-f5w6fw6q 126 31 purposes purpose NNS cord-006870-f5w6fw6q 126 32 . . . cord-006870-f5w6fw6q 127 1 Students student NNS cord-006870-f5w6fw6q 127 2 correctly correctly RB cord-006870-f5w6fw6q 127 3 answered answer VBD cord-006870-f5w6fw6q 127 4 a a DT cord-006870-f5w6fw6q 127 5 median median NN cord-006870-f5w6fw6q 127 6 of of IN cord-006870-f5w6fw6q 127 7 53 53 CD cord-006870-f5w6fw6q 127 8 % % NN cord-006870-f5w6fw6q 127 9 of of IN cord-006870-f5w6fw6q 127 10 questions question NNS cord-006870-f5w6fw6q 127 11 ( ( -LRB- cord-006870-f5w6fw6q 127 12 IQR IQR NNP cord-006870-f5w6fw6q 127 13 47 47 CD cord-006870-f5w6fw6q 127 14 - - SYM cord-006870-f5w6fw6q 127 15 58 58 CD cord-006870-f5w6fw6q 127 16 % % NN cord-006870-f5w6fw6q 127 17 ) ) -RRB- cord-006870-f5w6fw6q 127 18 on on IN cord-006870-f5w6fw6q 127 19 the the DT cord-006870-f5w6fw6q 127 20 pretest pretest NN cord-006870-f5w6fw6q 127 21 and and CC cord-006870-f5w6fw6q 127 22 86 86 CD cord-006870-f5w6fw6q 127 23 % % NN cord-006870-f5w6fw6q 127 24 of of IN cord-006870-f5w6fw6q 127 25 questions question NNS cord-006870-f5w6fw6q 127 26 ( ( -LRB- cord-006870-f5w6fw6q 127 27 IQR IQR NNP cord-006870-f5w6fw6q 127 28 78 78 CD cord-006870-f5w6fw6q 127 29 - - SYM cord-006870-f5w6fw6q 127 30 89 89 CD cord-006870-f5w6fw6q 127 31 % % NN cord-006870-f5w6fw6q 127 32 ) ) -RRB- cord-006870-f5w6fw6q 127 33 on on IN cord-006870-f5w6fw6q 127 34 the the DT cord-006870-f5w6fw6q 127 35 posttest posttest NNP cord-006870-f5w6fw6q 127 36 ( ( -LRB- cord-006870-f5w6fw6q 127 37 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 127 38 ) ) -RRB- cord-006870-f5w6fw6q 127 39 . . . cord-006870-f5w6fw6q 128 1 Comfort comfort NN cord-006870-f5w6fw6q 128 2 with with IN cord-006870-f5w6fw6q 128 3 both both DT cord-006870-f5w6fw6q 128 4 performing perform VBG cord-006870-f5w6fw6q 128 5 a a DT cord-006870-f5w6fw6q 128 6 brain brain NN cord-006870-f5w6fw6q 128 7 death death NN cord-006870-f5w6fw6q 128 8 evaluation evaluation NN cord-006870-f5w6fw6q 128 9 and and CC cord-006870-f5w6fw6q 128 10 talking talk VBG cord-006870-f5w6fw6q 128 11 to to IN cord-006870-f5w6fw6q 128 12 a a DT cord-006870-f5w6fw6q 128 13 family family NN cord-006870-f5w6fw6q 128 14 about about IN cord-006870-f5w6fw6q 128 15 brain brain NN cord-006870-f5w6fw6q 128 16 death death NN cord-006870-f5w6fw6q 128 17 improved improve VBD cord-006870-f5w6fw6q 128 18 significantly significantly RB cord-006870-f5w6fw6q 128 19 after after IN cord-006870-f5w6fw6q 128 20 this this DT cord-006870-f5w6fw6q 128 21 initiative initiative NN cord-006870-f5w6fw6q 128 22 ( ( -LRB- cord-006870-f5w6fw6q 128 23 18 18 CD cord-006870-f5w6fw6q 128 24 % % NN cord-006870-f5w6fw6q 128 25 of of IN cord-006870-f5w6fw6q 128 26 students student NNS cord-006870-f5w6fw6q 128 27 were be VBD cord-006870-f5w6fw6q 128 28 comfortable comfortable JJ cord-006870-f5w6fw6q 128 29 performing perform VBG cord-006870-f5w6fw6q 128 30 a a DT cord-006870-f5w6fw6q 128 31 brain brain NN cord-006870-f5w6fw6q 128 32 death death NN cord-006870-f5w6fw6q 128 33 evaluation evaluation NN cord-006870-f5w6fw6q 128 34 before before IN cord-006870-f5w6fw6q 128 35 the the DT cord-006870-f5w6fw6q 128 36 initiative initiative NN cord-006870-f5w6fw6q 128 37 and and CC cord-006870-f5w6fw6q 128 38 86 86 CD cord-006870-f5w6fw6q 128 39 % % NN cord-006870-f5w6fw6q 128 40 were be VBD cord-006870-f5w6fw6q 128 41 comfortable comfortable JJ cord-006870-f5w6fw6q 128 42 doing do VBG cord-006870-f5w6fw6q 128 43 so so RB cord-006870-f5w6fw6q 128 44 after after IN cord-006870-f5w6fw6q 128 45 the the DT cord-006870-f5w6fw6q 128 46 initiative initiative NN cord-006870-f5w6fw6q 128 47 , , , cord-006870-f5w6fw6q 128 48 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 128 49 ; ; : cord-006870-f5w6fw6q 128 50 18 18 CD cord-006870-f5w6fw6q 128 51 % % NN cord-006870-f5w6fw6q 128 52 were be VBD cord-006870-f5w6fw6q 128 53 comfortable comfortable JJ cord-006870-f5w6fw6q 128 54 talking talk VBG cord-006870-f5w6fw6q 128 55 to to IN cord-006870-f5w6fw6q 128 56 a a DT cord-006870-f5w6fw6q 128 57 family family NN cord-006870-f5w6fw6q 128 58 about about IN cord-006870-f5w6fw6q 128 59 brain brain NN cord-006870-f5w6fw6q 128 60 death death NN cord-006870-f5w6fw6q 128 61 before before IN cord-006870-f5w6fw6q 128 62 the the DT cord-006870-f5w6fw6q 128 63 initiative initiative NN cord-006870-f5w6fw6q 128 64 and and CC cord-006870-f5w6fw6q 128 65 76 76 CD cord-006870-f5w6fw6q 128 66 % % NN cord-006870-f5w6fw6q 128 67 were be VBD cord-006870-f5w6fw6q 128 68 comfortable comfortable JJ cord-006870-f5w6fw6q 128 69 doing do VBG cord-006870-f5w6fw6q 128 70 so so RB cord-006870-f5w6fw6q 128 71 after after IN cord-006870-f5w6fw6q 128 72 the the DT cord-006870-f5w6fw6q 128 73 initiative initiative NN cord-006870-f5w6fw6q 128 74 , , , cord-006870-f5w6fw6q 128 75 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 128 76 ) ) -RRB- cord-006870-f5w6fw6q 128 77 . . . cord-006870-f5w6fw6q 129 1 Incorporation incorporation NN cord-006870-f5w6fw6q 129 2 of of IN cord-006870-f5w6fw6q 129 3 simulation simulation NN cord-006870-f5w6fw6q 129 4 in in IN cord-006870-f5w6fw6q 129 5 undergraduate undergraduate JJ cord-006870-f5w6fw6q 129 6 medical medical JJ cord-006870-f5w6fw6q 129 7 education education NN cord-006870-f5w6fw6q 129 8 is be VBZ cord-006870-f5w6fw6q 129 9 high high JJ cord-006870-f5w6fw6q 129 10 - - HYPH cord-006870-f5w6fw6q 129 11 yield yield NN cord-006870-f5w6fw6q 129 12 . . . cord-006870-f5w6fw6q 130 1 At at IN cord-006870-f5w6fw6q 130 2 our -PRON- PRP$ cord-006870-f5w6fw6q 130 3 medical medical JJ cord-006870-f5w6fw6q 130 4 school school NN cord-006870-f5w6fw6q 130 5 , , , cord-006870-f5w6fw6q 130 6 knowledge knowledge NN cord-006870-f5w6fw6q 130 7 about about IN cord-006870-f5w6fw6q 130 8 brain brain NN cord-006870-f5w6fw6q 130 9 death death NN cord-006870-f5w6fw6q 130 10 and and CC cord-006870-f5w6fw6q 130 11 comfort comfort NN cord-006870-f5w6fw6q 130 12 performing perform VBG cord-006870-f5w6fw6q 130 13 a a DT cord-006870-f5w6fw6q 130 14 brain brain NN cord-006870-f5w6fw6q 130 15 death death NN cord-006870-f5w6fw6q 130 16 exam exam NN cord-006870-f5w6fw6q 130 17 or or CC cord-006870-f5w6fw6q 130 18 talking talk VBG cord-006870-f5w6fw6q 130 19 to to IN cord-006870-f5w6fw6q 130 20 a a DT cord-006870-f5w6fw6q 130 21 family family NN cord-006870-f5w6fw6q 130 22 about about IN cord-006870-f5w6fw6q 130 23 brain brain NN cord-006870-f5w6fw6q 130 24 death death NN cord-006870-f5w6fw6q 130 25 was be VBD cord-006870-f5w6fw6q 130 26 poor poor JJ cord-006870-f5w6fw6q 130 27 prior prior RB cord-006870-f5w6fw6q 130 28 to to IN cord-006870-f5w6fw6q 130 29 development development NN cord-006870-f5w6fw6q 130 30 of of IN cord-006870-f5w6fw6q 130 31 this this DT cord-006870-f5w6fw6q 130 32 initiative initiative NN cord-006870-f5w6fw6q 130 33 , , , cord-006870-f5w6fw6q 130 34 but but CC cord-006870-f5w6fw6q 130 35 awareness awareness NN cord-006870-f5w6fw6q 130 36 and and CC cord-006870-f5w6fw6q 130 37 comfort comfort NN cord-006870-f5w6fw6q 130 38 dealing deal VBG cord-006870-f5w6fw6q 130 39 with with IN cord-006870-f5w6fw6q 130 40 brain brain NN cord-006870-f5w6fw6q 130 41 death death NN cord-006870-f5w6fw6q 130 42 improved improve VBD cord-006870-f5w6fw6q 130 43 significantly significantly RB cord-006870-f5w6fw6q 130 44 after after IN cord-006870-f5w6fw6q 130 45 this this DT cord-006870-f5w6fw6q 130 46 initiative initiative NN cord-006870-f5w6fw6q 130 47 . . . cord-006870-f5w6fw6q 131 1 This this DT cord-006870-f5w6fw6q 131 2 initiative initiative NN cord-006870-f5w6fw6q 131 3 was be VBD cord-006870-f5w6fw6q 131 4 clearly clearly RB cord-006870-f5w6fw6q 131 5 a a DT cord-006870-f5w6fw6q 131 6 success success NN cord-006870-f5w6fw6q 131 7 and and CC cord-006870-f5w6fw6q 131 8 can can MD cord-006870-f5w6fw6q 131 9 serve serve VB cord-006870-f5w6fw6q 131 10 as as IN cord-006870-f5w6fw6q 131 11 a a DT cord-006870-f5w6fw6q 131 12 model model NN cord-006870-f5w6fw6q 131 13 for for IN cord-006870-f5w6fw6q 131 14 brain brain NN cord-006870-f5w6fw6q 131 15 death death NN cord-006870-f5w6fw6q 131 16 education education NN cord-006870-f5w6fw6q 131 17 at at IN cord-006870-f5w6fw6q 131 18 other other JJ cord-006870-f5w6fw6q 131 19 medical medical JJ cord-006870-f5w6fw6q 131 20 schools school NNS cord-006870-f5w6fw6q 131 21 . . . cord-006870-f5w6fw6q 132 1 Early early JJ cord-006870-f5w6fw6q 132 2 withdrawal withdrawal NN cord-006870-f5w6fw6q 132 3 of of IN cord-006870-f5w6fw6q 132 4 life life NN cord-006870-f5w6fw6q 132 5 support support NN cord-006870-f5w6fw6q 132 6 ( ( -LRB- cord-006870-f5w6fw6q 132 7 EWLS EWLS NNP cord-006870-f5w6fw6q 132 8 ) ) -RRB- cord-006870-f5w6fw6q 132 9 is be VBZ cord-006870-f5w6fw6q 132 10 a a DT cord-006870-f5w6fw6q 132 11 major major JJ cord-006870-f5w6fw6q 132 12 factor factor NN cord-006870-f5w6fw6q 132 13 in in IN cord-006870-f5w6fw6q 132 14 deaths death NNS cord-006870-f5w6fw6q 132 15 following follow VBG cord-006870-f5w6fw6q 132 16 hypoxic hypoxic JJ cord-006870-f5w6fw6q 132 17 ischemic ischemic JJ cord-006870-f5w6fw6q 132 18 injury injury NN cord-006870-f5w6fw6q 132 19 after after IN cord-006870-f5w6fw6q 132 20 cardiac cardiac JJ cord-006870-f5w6fw6q 132 21 arrest arrest NN cord-006870-f5w6fw6q 132 22 ( ( -LRB- cord-006870-f5w6fw6q 132 23 CA CA NNP cord-006870-f5w6fw6q 132 24 ) ) -RRB- cord-006870-f5w6fw6q 132 25 in in IN cord-006870-f5w6fw6q 132 26 patients patient NNS cord-006870-f5w6fw6q 132 27 receiving receive VBG cord-006870-f5w6fw6q 132 28 targeted target VBN cord-006870-f5w6fw6q 132 29 temperature temperature NN cord-006870-f5w6fw6q 132 30 management management NN cord-006870-f5w6fw6q 132 31 ( ( -LRB- cord-006870-f5w6fw6q 132 32 TTM TTM NNP cord-006870-f5w6fw6q 132 33 ) ) -RRB- cord-006870-f5w6fw6q 132 34 . . . cord-006870-f5w6fw6q 133 1 Appropriate appropriate JJ cord-006870-f5w6fw6q 133 2 timing timing NN cord-006870-f5w6fw6q 133 3 of of IN cord-006870-f5w6fw6q 133 4 prognostication prognostication NN cord-006870-f5w6fw6q 133 5 , , , cord-006870-f5w6fw6q 133 6 and and CC cord-006870-f5w6fw6q 133 7 subsequent subsequent JJ cord-006870-f5w6fw6q 133 8 withdrawal withdrawal NN cord-006870-f5w6fw6q 133 9 of of IN cord-006870-f5w6fw6q 133 10 life life NN cord-006870-f5w6fw6q 133 11 support support NN cord-006870-f5w6fw6q 133 12 is be VBZ cord-006870-f5w6fw6q 133 13 recommended recommend VBN cord-006870-f5w6fw6q 133 14 in in IN cord-006870-f5w6fw6q 133 15 recent recent JJ cord-006870-f5w6fw6q 133 16 guidelines guideline NNS cord-006870-f5w6fw6q 133 17 , , , cord-006870-f5w6fw6q 133 18 but but CC cord-006870-f5w6fw6q 133 19 is be VBZ cord-006870-f5w6fw6q 133 20 not not RB cord-006870-f5w6fw6q 133 21 always always RB cord-006870-f5w6fw6q 133 22 followed follow VBN cord-006870-f5w6fw6q 133 23 in in IN cord-006870-f5w6fw6q 133 24 clinical clinical JJ cord-006870-f5w6fw6q 133 25 practice practice NN cord-006870-f5w6fw6q 133 26 . . . cord-006870-f5w6fw6q 134 1 We -PRON- PRP cord-006870-f5w6fw6q 134 2 describe describe VBP cord-006870-f5w6fw6q 134 3 the the DT cord-006870-f5w6fw6q 134 4 impact impact NN cord-006870-f5w6fw6q 134 5 of of IN cord-006870-f5w6fw6q 134 6 EWLS EWLS NNP cord-006870-f5w6fw6q 134 7 in in IN cord-006870-f5w6fw6q 134 8 a a DT cord-006870-f5w6fw6q 134 9 multicenter multicenter JJ cord-006870-f5w6fw6q 134 10 registry registry NN cord-006870-f5w6fw6q 134 11 database database NN cord-006870-f5w6fw6q 134 12 . . . cord-006870-f5w6fw6q 135 1 Using use VBG cord-006870-f5w6fw6q 135 2 data datum NNS cord-006870-f5w6fw6q 135 3 from from IN cord-006870-f5w6fw6q 135 4 the the DT cord-006870-f5w6fw6q 135 5 International International NNP cord-006870-f5w6fw6q 135 6 Cardiac Cardiac NNP cord-006870-f5w6fw6q 135 7 Arrest Arrest NNP cord-006870-f5w6fw6q 135 8 Registry Registry NNP cord-006870-f5w6fw6q 135 9 ( ( -LRB- cord-006870-f5w6fw6q 135 10 INTCAR INTCAR NNP cord-006870-f5w6fw6q 135 11 ) ) -RRB- cord-006870-f5w6fw6q 135 12 , , , cord-006870-f5w6fw6q 135 13 we -PRON- PRP cord-006870-f5w6fw6q 135 14 defined define VBD cord-006870-f5w6fw6q 135 15 EWLS EWLS NNP cord-006870-f5w6fw6q 135 16 as as IN cord-006870-f5w6fw6q 135 17 withdrawal withdrawal NN cord-006870-f5w6fw6q 135 18 in in IN cord-006870-f5w6fw6q 135 19 the the DT cord-006870-f5w6fw6q 135 20 first first JJ cord-006870-f5w6fw6q 135 21 three three CD cord-006870-f5w6fw6q 135 22 days day NNS cord-006870-f5w6fw6q 135 23 of of IN cord-006870-f5w6fw6q 135 24 hospitalization hospitalization NN cord-006870-f5w6fw6q 135 25 . . . cord-006870-f5w6fw6q 136 1 Among among IN cord-006870-f5w6fw6q 136 2 all all DT cord-006870-f5w6fw6q 136 3 patients patient NNS cord-006870-f5w6fw6q 136 4 treated treat VBN cord-006870-f5w6fw6q 136 5 with with IN cord-006870-f5w6fw6q 136 6 targeted target VBN cord-006870-f5w6fw6q 136 7 temperature temperature NN cord-006870-f5w6fw6q 136 8 management management NN cord-006870-f5w6fw6q 136 9 , , , cord-006870-f5w6fw6q 136 10 we -PRON- PRP cord-006870-f5w6fw6q 136 11 developed develop VBD cord-006870-f5w6fw6q 136 12 a a DT cord-006870-f5w6fw6q 136 13 logistic logistic JJ cord-006870-f5w6fw6q 136 14 regression regression NN cord-006870-f5w6fw6q 136 15 model model NN cord-006870-f5w6fw6q 136 16 to to TO cord-006870-f5w6fw6q 136 17 predict predict VB cord-006870-f5w6fw6q 136 18 EWLS EWLS NNP cord-006870-f5w6fw6q 136 19 . . . cord-006870-f5w6fw6q 137 1 We -PRON- PRP cord-006870-f5w6fw6q 137 2 then then RB cord-006870-f5w6fw6q 137 3 performed perform VBD cord-006870-f5w6fw6q 137 4 a a DT cord-006870-f5w6fw6q 137 5 propensity propensity NN cord-006870-f5w6fw6q 137 6 score score NN cord-006870-f5w6fw6q 137 7 and and CC cord-006870-f5w6fw6q 137 8 evaluated evaluate VBD cord-006870-f5w6fw6q 137 9 the the DT cord-006870-f5w6fw6q 137 10 incidence incidence NN cord-006870-f5w6fw6q 137 11 of of IN cord-006870-f5w6fw6q 137 12 good good JJ cord-006870-f5w6fw6q 137 13 outcome outcome NN cord-006870-f5w6fw6q 137 14 between between IN cord-006870-f5w6fw6q 137 15 deciles decile NNS cord-006870-f5w6fw6q 137 16 of of IN cord-006870-f5w6fw6q 137 17 risk risk NN cord-006870-f5w6fw6q 137 18 for for IN cord-006870-f5w6fw6q 137 19 EWLS EWLS NNP cord-006870-f5w6fw6q 137 20 . . . cord-006870-f5w6fw6q 138 1 1311 1311 CD cord-006870-f5w6fw6q 138 2 patients patient NNS cord-006870-f5w6fw6q 138 3 entered enter VBD cord-006870-f5w6fw6q 138 4 into into IN cord-006870-f5w6fw6q 138 5 INTCAR INTCAR NNP cord-006870-f5w6fw6q 138 6 from from IN cord-006870-f5w6fw6q 138 7 2012 2012 CD cord-006870-f5w6fw6q 138 8 - - SYM cord-006870-f5w6fw6q 138 9 2016 2016 CD cord-006870-f5w6fw6q 138 10 from from IN cord-006870-f5w6fw6q 138 11 16 16 CD cord-006870-f5w6fw6q 138 12 different different JJ cord-006870-f5w6fw6q 138 13 hospitals hospital NNS cord-006870-f5w6fw6q 138 14 were be VBD cord-006870-f5w6fw6q 138 15 included include VBN cord-006870-f5w6fw6q 138 16 . . . cord-006870-f5w6fw6q 139 1 Mean mean JJ cord-006870-f5w6fw6q 139 2 age age NN cord-006870-f5w6fw6q 139 3 was be VBD cord-006870-f5w6fw6q 139 4 62 62 CD cord-006870-f5w6fw6q 140 1 ( ( -LRB- cord-006870-f5w6fw6q 140 2 ±16 ±16 NNP cord-006870-f5w6fw6q 140 3 ) ) -RRB- cord-006870-f5w6fw6q 140 4 years year NNS cord-006870-f5w6fw6q 140 5 , , , cord-006870-f5w6fw6q 140 6 mean mean VB cord-006870-f5w6fw6q 140 7 CPR CPR NNP cord-006870-f5w6fw6q 140 8 duration duration NN cord-006870-f5w6fw6q 140 9 was be VBD cord-006870-f5w6fw6q 140 10 28 28 CD cord-006870-f5w6fw6q 140 11 ( ( -LRB- cord-006870-f5w6fw6q 141 1 ± ± NNP cord-006870-f5w6fw6q 141 2 21 21 CD cord-006870-f5w6fw6q 141 3 ) ) -RRB- cord-006870-f5w6fw6q 141 4 minutes minute NNS cord-006870-f5w6fw6q 141 5 , , , cord-006870-f5w6fw6q 141 6 689 689 CD cord-006870-f5w6fw6q 141 7 ( ( -LRB- cord-006870-f5w6fw6q 141 8 53 53 CD cord-006870-f5w6fw6q 141 9 % % NN cord-006870-f5w6fw6q 141 10 ) ) -RRB- cord-006870-f5w6fw6q 141 11 had have VBD cord-006870-f5w6fw6q 141 12 a a DT cord-006870-f5w6fw6q 141 13 shockable shockable JJ cord-006870-f5w6fw6q 141 14 rhythm rhythm NN cord-006870-f5w6fw6q 141 15 , , , cord-006870-f5w6fw6q 141 16 and and CC cord-006870-f5w6fw6q 141 17 812 812 CD cord-006870-f5w6fw6q 141 18 ( ( -LRB- cord-006870-f5w6fw6q 141 19 62 62 CD cord-006870-f5w6fw6q 141 20 % % NN cord-006870-f5w6fw6q 141 21 ) ) -RRB- cord-006870-f5w6fw6q 142 1 received receive VBD cord-006870-f5w6fw6q 142 2 bystander bystander NN cord-006870-f5w6fw6q 142 3 CPR CPR NNP cord-006870-f5w6fw6q 142 4 . . . cord-006870-f5w6fw6q 143 1 Support support NN cord-006870-f5w6fw6q 143 2 was be VBD cord-006870-f5w6fw6q 143 3 withdrawn withdraw VBN cord-006870-f5w6fw6q 143 4 in in IN cord-006870-f5w6fw6q 143 5 609 609 CD cord-006870-f5w6fw6q 143 6 , , , cord-006870-f5w6fw6q 143 7 with with IN cord-006870-f5w6fw6q 143 8 336 336 CD cord-006870-f5w6fw6q 143 9 ( ( -LRB- cord-006870-f5w6fw6q 143 10 55 55 CD cord-006870-f5w6fw6q 143 11 % % NN cord-006870-f5w6fw6q 143 12 ) ) -RRB- cord-006870-f5w6fw6q 143 13 events event NNS cord-006870-f5w6fw6q 143 14 classified classify VBN cord-006870-f5w6fw6q 143 15 as as IN cord-006870-f5w6fw6q 143 16 EWLS EWLS NNP cord-006870-f5w6fw6q 143 17 . . . cord-006870-f5w6fw6q 144 1 ( ( -LRB- cord-006870-f5w6fw6q 144 2 26 26 CD cord-006870-f5w6fw6q 144 3 % % NN cord-006870-f5w6fw6q 144 4 of of IN cord-006870-f5w6fw6q 144 5 total total JJ cord-006870-f5w6fw6q 144 6 cohort cohort NN cord-006870-f5w6fw6q 144 7 ) ) -RRB- cord-006870-f5w6fw6q 144 8 . . . cord-006870-f5w6fw6q 145 1 Among among IN cord-006870-f5w6fw6q 145 2 patients patient NNS cord-006870-f5w6fw6q 145 3 with with IN cord-006870-f5w6fw6q 145 4 support support NN cord-006870-f5w6fw6q 145 5 withdrawal withdrawal NN cord-006870-f5w6fw6q 145 6 , , , cord-006870-f5w6fw6q 145 7 older old JJR cord-006870-f5w6fw6q 145 8 age age NN cord-006870-f5w6fw6q 145 9 ( ( -LRB- cord-006870-f5w6fw6q 145 10 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 145 11 ) ) -RRB- cord-006870-f5w6fw6q 145 12 , , , cord-006870-f5w6fw6q 145 13 nonshockable nonshockable JJ cord-006870-f5w6fw6q 145 14 rhythm rhythm NN cord-006870-f5w6fw6q 145 15 ( ( -LRB- cord-006870-f5w6fw6q 145 16 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 145 17 ) ) -RRB- cord-006870-f5w6fw6q 145 18 , , , cord-006870-f5w6fw6q 145 19 increased increase VBN cord-006870-f5w6fw6q 145 20 ischemic ischemic JJ cord-006870-f5w6fw6q 145 21 time time NN cord-006870-f5w6fw6q 145 22 ( ( -LRB- cord-006870-f5w6fw6q 145 23 p=0.03 p=0.03 NNP cord-006870-f5w6fw6q 145 24 ) ) -RRB- cord-006870-f5w6fw6q 145 25 , , , cord-006870-f5w6fw6q 145 26 and and CC cord-006870-f5w6fw6q 145 27 shock shock NN cord-006870-f5w6fw6q 145 28 on on IN cord-006870-f5w6fw6q 145 29 admission admission NN cord-006870-f5w6fw6q 145 30 ( ( -LRB- cord-006870-f5w6fw6q 145 31 p<0.001 p<0.001 NNS cord-006870-f5w6fw6q 145 32 ) ) -RRB- cord-006870-f5w6fw6q 145 33 were be VBD cord-006870-f5w6fw6q 145 34 associated associate VBN cord-006870-f5w6fw6q 145 35 with with IN cord-006870-f5w6fw6q 145 36 EWLS EWLS NNP cord-006870-f5w6fw6q 145 37 . . . cord-006870-f5w6fw6q 146 1 Among among IN cord-006870-f5w6fw6q 146 2 propensity propensity NN cord-006870-f5w6fw6q 146 3 matched match VBN cord-006870-f5w6fw6q 146 4 patients patient NNS cord-006870-f5w6fw6q 146 5 grouped group VBN cord-006870-f5w6fw6q 146 6 into into IN cord-006870-f5w6fw6q 146 7 deciles decile NNS cord-006870-f5w6fw6q 146 8 of of IN cord-006870-f5w6fw6q 146 9 probability probability NN cord-006870-f5w6fw6q 146 10 for for IN cord-006870-f5w6fw6q 146 11 EWLS EWLS NNP cord-006870-f5w6fw6q 146 12 , , , cord-006870-f5w6fw6q 146 13 survival survival NN cord-006870-f5w6fw6q 146 14 with with IN cord-006870-f5w6fw6q 146 15 good good JJ cord-006870-f5w6fw6q 146 16 functional functional JJ cord-006870-f5w6fw6q 146 17 outcome outcome NN cord-006870-f5w6fw6q 146 18 occurred occur VBD cord-006870-f5w6fw6q 146 19 in in IN cord-006870-f5w6fw6q 146 20 18 18 CD cord-006870-f5w6fw6q 146 21 % % NN cord-006870-f5w6fw6q 146 22 ( ( -LRB- cord-006870-f5w6fw6q 146 23 6th 6th JJ cord-006870-f5w6fw6q 146 24 decile decile NN cord-006870-f5w6fw6q 146 25 ) ) -RRB- cord-006870-f5w6fw6q 146 26 , , , cord-006870-f5w6fw6q 146 27 30 30 CD cord-006870-f5w6fw6q 146 28 % % NN cord-006870-f5w6fw6q 146 29 ( ( -LRB- cord-006870-f5w6fw6q 146 30 7th 7th NN cord-006870-f5w6fw6q 146 31 ) ) -RRB- cord-006870-f5w6fw6q 146 32 , , , cord-006870-f5w6fw6q 146 33 10 10 CD cord-006870-f5w6fw6q 146 34 % % NN cord-006870-f5w6fw6q 146 35 ( ( -LRB- cord-006870-f5w6fw6q 146 36 8th 8th NN cord-006870-f5w6fw6q 146 37 ) ) -RRB- cord-006870-f5w6fw6q 146 38 , , , cord-006870-f5w6fw6q 146 39 6 6 CD cord-006870-f5w6fw6q 146 40 % % NN cord-006870-f5w6fw6q 146 41 ( ( -LRB- cord-006870-f5w6fw6q 146 42 9th 9th NN cord-006870-f5w6fw6q 146 43 ) ) -RRB- cord-006870-f5w6fw6q 146 44 , , , cord-006870-f5w6fw6q 146 45 and and CC cord-006870-f5w6fw6q 146 46 12 12 CD cord-006870-f5w6fw6q 146 47 % % NN cord-006870-f5w6fw6q 146 48 ( ( -LRB- cord-006870-f5w6fw6q 146 49 10th 10th JJ cord-006870-f5w6fw6q 146 50 decile decile NN cord-006870-f5w6fw6q 146 51 ) ) -RRB- cord-006870-f5w6fw6q 146 52 . . . cord-006870-f5w6fw6q 147 1 Early early JJ cord-006870-f5w6fw6q 147 2 withdrawal withdrawal NN cord-006870-f5w6fw6q 147 3 of of IN cord-006870-f5w6fw6q 147 4 life life NN cord-006870-f5w6fw6q 147 5 support support NN cord-006870-f5w6fw6q 147 6 after after IN cord-006870-f5w6fw6q 147 7 cardiac cardiac JJ cord-006870-f5w6fw6q 147 8 arrest arrest NN cord-006870-f5w6fw6q 147 9 occurs occur VBZ cord-006870-f5w6fw6q 147 10 frequently frequently RB cord-006870-f5w6fw6q 147 11 , , , cord-006870-f5w6fw6q 147 12 and and CC cord-006870-f5w6fw6q 147 13 is be VBZ cord-006870-f5w6fw6q 147 14 associated associate VBN cord-006870-f5w6fw6q 147 15 with with IN cord-006870-f5w6fw6q 147 16 age age NN cord-006870-f5w6fw6q 147 17 , , , cord-006870-f5w6fw6q 147 18 duration duration NN cord-006870-f5w6fw6q 147 19 of of IN cord-006870-f5w6fw6q 147 20 CPR CPR NNP cord-006870-f5w6fw6q 147 21 , , , cord-006870-f5w6fw6q 147 22 a a DT cord-006870-f5w6fw6q 147 23 non non JJ cord-006870-f5w6fw6q 147 24 - - JJ cord-006870-f5w6fw6q 147 25 shockable shockable JJ cord-006870-f5w6fw6q 147 26 rhythm rhythm NN cord-006870-f5w6fw6q 147 27 , , , cord-006870-f5w6fw6q 147 28 and and CC cord-006870-f5w6fw6q 147 29 shock shock NN cord-006870-f5w6fw6q 147 30 at at IN cord-006870-f5w6fw6q 147 31 the the DT cord-006870-f5w6fw6q 147 32 time time NN cord-006870-f5w6fw6q 147 33 of of IN cord-006870-f5w6fw6q 147 34 admission admission NN cord-006870-f5w6fw6q 147 35 . . . cord-006870-f5w6fw6q 148 1 A a DT cord-006870-f5w6fw6q 148 2 cohort cohort NN cord-006870-f5w6fw6q 148 3 of of IN cord-006870-f5w6fw6q 148 4 patients patient NNS cord-006870-f5w6fw6q 148 5 propensity propensity NN cord-006870-f5w6fw6q 148 6 - - HYPH cord-006870-f5w6fw6q 148 7 matched match VBN cord-006870-f5w6fw6q 148 8 to to IN cord-006870-f5w6fw6q 148 9 those those DT cord-006870-f5w6fw6q 148 10 with with IN cord-006870-f5w6fw6q 148 11 EWLS EWLS NNP cord-006870-f5w6fw6q 148 12 had have VBD cord-006870-f5w6fw6q 148 13 6 6 CD cord-006870-f5w6fw6q 148 14 - - SYM cord-006870-f5w6fw6q 148 15 30 30 CD cord-006870-f5w6fw6q 148 16 % % NN cord-006870-f5w6fw6q 148 17 survival survival NN cord-006870-f5w6fw6q 148 18 with with IN cord-006870-f5w6fw6q 148 19 favorable favorable JJ cord-006870-f5w6fw6q 148 20 neurologic neurologic JJ cord-006870-f5w6fw6q 148 21 outcomes outcome NNS cord-006870-f5w6fw6q 148 22 . . . cord-006870-f5w6fw6q 149 1 These these DT cord-006870-f5w6fw6q 149 2 data datum NNS cord-006870-f5w6fw6q 149 3 support support VBP cord-006870-f5w6fw6q 149 4 that that IN cord-006870-f5w6fw6q 149 5 in in IN cord-006870-f5w6fw6q 149 6 most most JJS cord-006870-f5w6fw6q 149 7 patients patient NNS cord-006870-f5w6fw6q 149 8 receiving receive VBG cord-006870-f5w6fw6q 149 9 TTM TTM NNP cord-006870-f5w6fw6q 149 10 , , , cord-006870-f5w6fw6q 149 11 conservative conservative JJ cord-006870-f5w6fw6q 149 12 and and CC cord-006870-f5w6fw6q 149 13 delayed delayed JJ cord-006870-f5w6fw6q 149 14 prognostication prognostication NN cord-006870-f5w6fw6q 149 15 after after IN cord-006870-f5w6fw6q 149 16 cardiac cardiac JJ cord-006870-f5w6fw6q 149 17 arrest arrest NN cord-006870-f5w6fw6q 149 18 is be VBZ cord-006870-f5w6fw6q 149 19 appropriate appropriate JJ cord-006870-f5w6fw6q 149 20 . . . cord-006870-f5w6fw6q 150 1 Brain brain NN cord-006870-f5w6fw6q 150 2 herniation herniation NN cord-006870-f5w6fw6q 150 3 ( ( -LRB- cord-006870-f5w6fw6q 150 4 BH BH NNP cord-006870-f5w6fw6q 150 5 ) ) -RRB- cord-006870-f5w6fw6q 150 6 is be VBZ cord-006870-f5w6fw6q 150 7 a a DT cord-006870-f5w6fw6q 150 8 deadly deadly JJ cord-006870-f5w6fw6q 150 9 event event NN cord-006870-f5w6fw6q 150 10 that that WDT cord-006870-f5w6fw6q 150 11 requires require VBZ cord-006870-f5w6fw6q 150 12 immediate immediate JJ cord-006870-f5w6fw6q 150 13 central central JJ cord-006870-f5w6fw6q 150 14 venous venous JJ cord-006870-f5w6fw6q 150 15 access access NN cord-006870-f5w6fw6q 150 16 for for IN cord-006870-f5w6fw6q 150 17 infusion infusion NN cord-006870-f5w6fw6q 150 18 of of IN cord-006870-f5w6fw6q 150 19 hyperosmotic hyperosmotic JJ cord-006870-f5w6fw6q 150 20 agents agent NNS cord-006870-f5w6fw6q 150 21 , , , cord-006870-f5w6fw6q 150 22 especially especially RB cord-006870-f5w6fw6q 150 23 23.4 23.4 CD cord-006870-f5w6fw6q 150 24 % % NN cord-006870-f5w6fw6q 150 25 NaCl nacl NN cord-006870-f5w6fw6q 150 26 . . . cord-006870-f5w6fw6q 151 1 Traditional traditional JJ cord-006870-f5w6fw6q 151 2 venous venous JJ cord-006870-f5w6fw6q 151 3 catheters catheter NNS cord-006870-f5w6fw6q 151 4 , , , cord-006870-f5w6fw6q 151 5 whether whether IN cord-006870-f5w6fw6q 151 6 peripheral peripheral JJ cord-006870-f5w6fw6q 151 7 or or CC cord-006870-f5w6fw6q 151 8 central central JJ cord-006870-f5w6fw6q 151 9 , , , cord-006870-f5w6fw6q 151 10 takes take VBZ cord-006870-f5w6fw6q 151 11 several several JJ cord-006870-f5w6fw6q 151 12 minutes minute NNS cord-006870-f5w6fw6q 151 13 to to TO cord-006870-f5w6fw6q 151 14 place place VB cord-006870-f5w6fw6q 151 15 , , , cord-006870-f5w6fw6q 151 16 and and CC cord-006870-f5w6fw6q 151 17 requires require VBZ cord-006870-f5w6fw6q 151 18 skill skill NN cord-006870-f5w6fw6q 151 19 for for IN cord-006870-f5w6fw6q 151 20 successful successful JJ cord-006870-f5w6fw6q 151 21 placement placement NN cord-006870-f5w6fw6q 151 22 , , , cord-006870-f5w6fw6q 151 23 thus thus RB cord-006870-f5w6fw6q 151 24 delaying delay VBG cord-006870-f5w6fw6q 151 25 critical critical JJ cord-006870-f5w6fw6q 151 26 treatment treatment NN cord-006870-f5w6fw6q 151 27 . . . cord-006870-f5w6fw6q 152 1 Intraosseous Intraosseous NNP cord-006870-f5w6fw6q 152 2 ( ( -LRB- cord-006870-f5w6fw6q 152 3 IO IO NNP cord-006870-f5w6fw6q 152 4 ) ) -RRB- cord-006870-f5w6fw6q 152 5 cannulation cannulation NN cord-006870-f5w6fw6q 152 6 has have VBZ cord-006870-f5w6fw6q 152 7 been be VBN cord-006870-f5w6fw6q 152 8 shown show VBN cord-006870-f5w6fw6q 152 9 , , , cord-006870-f5w6fw6q 152 10 at at IN cord-006870-f5w6fw6q 152 11 least least JJS cord-006870-f5w6fw6q 152 12 during during IN cord-006870-f5w6fw6q 152 13 cardiac cardiac JJ cord-006870-f5w6fw6q 152 14 arrest arrest NN cord-006870-f5w6fw6q 152 15 , , , cord-006870-f5w6fw6q 152 16 to to TO cord-006870-f5w6fw6q 152 17 be be VB cord-006870-f5w6fw6q 152 18 a a DT cord-006870-f5w6fw6q 152 19 secure secure JJ cord-006870-f5w6fw6q 152 20 and and CC cord-006870-f5w6fw6q 152 21 rapid rapid JJ cord-006870-f5w6fw6q 152 22 means mean NNS cord-006870-f5w6fw6q 152 23 of of IN cord-006870-f5w6fw6q 152 24 central central JJ cord-006870-f5w6fw6q 152 25 vascular vascular JJ cord-006870-f5w6fw6q 152 26 access access NN cord-006870-f5w6fw6q 152 27 that that WDT cord-006870-f5w6fw6q 152 28 requires require VBZ cord-006870-f5w6fw6q 152 29 limited limited JJ cord-006870-f5w6fw6q 152 30 training training NN cord-006870-f5w6fw6q 152 31 . . . cord-006870-f5w6fw6q 153 1 However however RB cord-006870-f5w6fw6q 153 2 , , , cord-006870-f5w6fw6q 153 3 limited limited JJ cord-006870-f5w6fw6q 153 4 data data NN cord-006870-f5w6fw6q 153 5 exists exist VBZ cord-006870-f5w6fw6q 153 6 on on IN cord-006870-f5w6fw6q 153 7 the the DT cord-006870-f5w6fw6q 153 8 use use NN cord-006870-f5w6fw6q 153 9 of of IN cord-006870-f5w6fw6q 153 10 IO IO NNP cord-006870-f5w6fw6q 153 11 in in IN cord-006870-f5w6fw6q 153 12 BH BH NNP cord-006870-f5w6fw6q 153 13 for for IN cord-006870-f5w6fw6q 153 14 administering administer VBG cord-006870-f5w6fw6q 153 15 23.4 23.4 CD cord-006870-f5w6fw6q 153 16 % % NN cord-006870-f5w6fw6q 153 17 . . . cord-006870-f5w6fw6q 154 1 The the DT cord-006870-f5w6fw6q 154 2 aim aim NN cord-006870-f5w6fw6q 154 3 of of IN cord-006870-f5w6fw6q 154 4 study study NN cord-006870-f5w6fw6q 154 5 of of IN cord-006870-f5w6fw6q 154 6 this this DT cord-006870-f5w6fw6q 154 7 study study NN cord-006870-f5w6fw6q 154 8 is be VBZ cord-006870-f5w6fw6q 154 9 to to TO cord-006870-f5w6fw6q 154 10 measure measure VB cord-006870-f5w6fw6q 154 11 changes change NNS cord-006870-f5w6fw6q 154 12 in in IN cord-006870-f5w6fw6q 154 13 serum serum NN cord-006870-f5w6fw6q 154 14 sodium sodium NN cord-006870-f5w6fw6q 154 15 and and CC cord-006870-f5w6fw6q 154 16 BH BH NNP cord-006870-f5w6fw6q 154 17 reversal reversal NN cord-006870-f5w6fw6q 154 18 after after IN cord-006870-f5w6fw6q 154 19 administering administer VBG cord-006870-f5w6fw6q 154 20 23.4 23.4 CD cord-006870-f5w6fw6q 154 21 % % NN cord-006870-f5w6fw6q 154 22 via via IN cord-006870-f5w6fw6q 154 23 IO IO NNP cord-006870-f5w6fw6q 154 24 . . . cord-006870-f5w6fw6q 155 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 155 2 chart chart NN cord-006870-f5w6fw6q 155 3 review review NN cord-006870-f5w6fw6q 155 4 of of IN cord-006870-f5w6fw6q 155 5 patients patient NNS cord-006870-f5w6fw6q 155 6 with with IN cord-006870-f5w6fw6q 155 7 acute acute JJ cord-006870-f5w6fw6q 155 8 neurologic neurologic JJ cord-006870-f5w6fw6q 155 9 injury injury NN cord-006870-f5w6fw6q 155 10 requiring require VBG cord-006870-f5w6fw6q 155 11 23.4 23.4 CD cord-006870-f5w6fw6q 155 12 % % NN cord-006870-f5w6fw6q 155 13 and and CC cord-006870-f5w6fw6q 155 14 IO IO NNP cord-006870-f5w6fw6q 155 15 placement placement NN cord-006870-f5w6fw6q 155 16 due due IN cord-006870-f5w6fw6q 155 17 to to IN cord-006870-f5w6fw6q 155 18 a a DT cord-006870-f5w6fw6q 155 19 lack lack NN cord-006870-f5w6fw6q 155 20 of of IN cord-006870-f5w6fw6q 155 21 central central JJ cord-006870-f5w6fw6q 155 22 access access NN cord-006870-f5w6fw6q 155 23 . . . cord-006870-f5w6fw6q 156 1 Demographics demographic NNS cord-006870-f5w6fw6q 156 2 , , , cord-006870-f5w6fw6q 156 3 diagnosis diagnosis NN cord-006870-f5w6fw6q 156 4 , , , cord-006870-f5w6fw6q 156 5 GCS GCS NNP cord-006870-f5w6fw6q 156 6 , , , cord-006870-f5w6fw6q 156 7 sodium sodium NN cord-006870-f5w6fw6q 156 8 ( ( -LRB- cord-006870-f5w6fw6q 156 9 Na+ Na+ NNP cord-006870-f5w6fw6q 156 10 ) ) -RRB- cord-006870-f5w6fw6q 156 11 , , , cord-006870-f5w6fw6q 156 12 and and CC cord-006870-f5w6fw6q 156 13 pupillary pupillary JJ cord-006870-f5w6fw6q 156 14 reactivity reactivity NN cord-006870-f5w6fw6q 156 15 , , , cord-006870-f5w6fw6q 156 16 and and CC cord-006870-f5w6fw6q 156 17 immediate immediate JJ cord-006870-f5w6fw6q 156 18 and and CC cord-006870-f5w6fw6q 156 19 delayed delayed JJ cord-006870-f5w6fw6q 156 20 complications complication NNS cord-006870-f5w6fw6q 156 21 were be VBD cord-006870-f5w6fw6q 156 22 collected collect VBN cord-006870-f5w6fw6q 156 23 . . . cord-006870-f5w6fw6q 157 1 Results result NNS cord-006870-f5w6fw6q 157 2 9 9 CD cord-006870-f5w6fw6q 157 3 patients patient NNS cord-006870-f5w6fw6q 157 4 included include VBD cord-006870-f5w6fw6q 157 5 : : : cord-006870-f5w6fw6q 157 6 4 4 CD cord-006870-f5w6fw6q 157 7 males male NNS cord-006870-f5w6fw6q 157 8 , , , cord-006870-f5w6fw6q 157 9 age age NN cord-006870-f5w6fw6q 157 10 range range VBP cord-006870-f5w6fw6q 157 11 33 33 CD cord-006870-f5w6fw6q 157 12 - - SYM cord-006870-f5w6fw6q 157 13 84 84 CD cord-006870-f5w6fw6q 157 14 yo yo NN cord-006870-f5w6fw6q 157 15 . . . cord-006870-f5w6fw6q 158 1 Diagnosis diagnosis NN cord-006870-f5w6fw6q 158 2 include include VBP cord-006870-f5w6fw6q 158 3 intracerebral intracerebral JJ cord-006870-f5w6fw6q 158 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 158 5 ( ( -LRB- cord-006870-f5w6fw6q 158 6 n=7 n=7 NNS cord-006870-f5w6fw6q 158 7 ) ) -RRB- cord-006870-f5w6fw6q 158 8 , , , cord-006870-f5w6fw6q 158 9 extra extra JJ cord-006870-f5w6fw6q 158 10 - - JJ cord-006870-f5w6fw6q 158 11 axial axial JJ cord-006870-f5w6fw6q 158 12 hematoma hematoma NN cord-006870-f5w6fw6q 158 13 ( ( -LRB- cord-006870-f5w6fw6q 158 14 n=1 n=1 FW cord-006870-f5w6fw6q 158 15 ) ) -RRB- cord-006870-f5w6fw6q 158 16 and and CC cord-006870-f5w6fw6q 158 17 SAH SAH NNP cord-006870-f5w6fw6q 158 18 ( ( -LRB- cord-006870-f5w6fw6q 158 19 n=1 n=1 NNP cord-006870-f5w6fw6q 158 20 ) ) -RRB- cord-006870-f5w6fw6q 158 21 . . . cord-006870-f5w6fw6q 159 1 GCS GCS NNP cord-006870-f5w6fw6q 159 2 ranged range VBD cord-006870-f5w6fw6q 159 3 3 3 CD cord-006870-f5w6fw6q 159 4 to to IN cord-006870-f5w6fw6q 159 5 8 8 CD cord-006870-f5w6fw6q 159 6 . . . cord-006870-f5w6fw6q 160 1 All all DT cord-006870-f5w6fw6q 160 2 patients patient NNS cord-006870-f5w6fw6q 160 3 were be VBD cord-006870-f5w6fw6q 160 4 intubated intubate VBN cord-006870-f5w6fw6q 160 5 . . . cord-006870-f5w6fw6q 161 1 Most Most JJS cord-006870-f5w6fw6q 161 2 patients patient NNS cord-006870-f5w6fw6q 161 3 were be VBD cord-006870-f5w6fw6q 161 4 co co VBN cord-006870-f5w6fw6q 161 5 - - VBN cord-006870-f5w6fw6q 161 6 treated treat VBN cord-006870-f5w6fw6q 161 7 with with IN cord-006870-f5w6fw6q 161 8 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 161 9 , , , cord-006870-f5w6fw6q 161 10 NaBicarb NaBicarb NNP cord-006870-f5w6fw6q 161 11 , , , cord-006870-f5w6fw6q 161 12 mannitol mannitol NN cord-006870-f5w6fw6q 161 13 , , , cord-006870-f5w6fw6q 161 14 and and CC cord-006870-f5w6fw6q 161 15 propofol propofol NN cord-006870-f5w6fw6q 161 16 . . . cord-006870-f5w6fw6q 162 1 IO IO NNP cord-006870-f5w6fw6q 162 2 was be VBD cord-006870-f5w6fw6q 162 3 placed place VBN cord-006870-f5w6fw6q 162 4 in in IN cord-006870-f5w6fw6q 162 5 tibia tibia NN cord-006870-f5w6fw6q 162 6 ( ( -LRB- cord-006870-f5w6fw6q 162 7 1 1 CD cord-006870-f5w6fw6q 162 8 ) ) -RRB- cord-006870-f5w6fw6q 162 9 or or CC cord-006870-f5w6fw6q 162 10 humerus humerus NNP cord-006870-f5w6fw6q 162 11 ( ( -LRB- cord-006870-f5w6fw6q 162 12 8) 8) NNP cord-006870-f5w6fw6q 162 13 ; ; : cord-006870-f5w6fw6q 162 14 all all DT cord-006870-f5w6fw6q 162 15 placed place VBN cord-006870-f5w6fw6q 162 16 correctly correctly RB cord-006870-f5w6fw6q 162 17 on on IN cord-006870-f5w6fw6q 162 18 first first JJ cord-006870-f5w6fw6q 162 19 attempt attempt NN cord-006870-f5w6fw6q 162 20 . . . cord-006870-f5w6fw6q 163 1 Comparing compare VBG cord-006870-f5w6fw6q 163 2 1 1 CD cord-006870-f5w6fw6q 163 3 hr hr NN cord-006870-f5w6fw6q 163 4 post-23.4 post-23.4 NNP cord-006870-f5w6fw6q 163 5 % % NN cord-006870-f5w6fw6q 163 6 NaCl nacl NN cord-006870-f5w6fw6q 163 7 treatment treatment NN cord-006870-f5w6fw6q 163 8 to to IN cord-006870-f5w6fw6q 163 9 pretreatment pretreatment NN cord-006870-f5w6fw6q 163 10 : : : cord-006870-f5w6fw6q 163 11 Na+ na+ CD cord-006870-f5w6fw6q 163 12 level level NN cord-006870-f5w6fw6q 163 13 increased increase VBD cord-006870-f5w6fw6q 163 14 in in IN cord-006870-f5w6fw6q 163 15 6 6 CD cord-006870-f5w6fw6q 163 16 of of IN cord-006870-f5w6fw6q 163 17 9 9 CD cord-006870-f5w6fw6q 163 18 ; ; : cord-006870-f5w6fw6q 163 19 GCS GCS NNP cord-006870-f5w6fw6q 163 20 improvement improvement NN cord-006870-f5w6fw6q 163 21 in in IN cord-006870-f5w6fw6q 163 22 4 4 CD cord-006870-f5w6fw6q 163 23 of of IN cord-006870-f5w6fw6q 163 24 9 9 CD cord-006870-f5w6fw6q 163 25 ; ; : cord-006870-f5w6fw6q 163 26 and and CC cord-006870-f5w6fw6q 163 27 returned return VBD cord-006870-f5w6fw6q 163 28 pupillary pupillary JJ cord-006870-f5w6fw6q 163 29 reactivity reactivity NN cord-006870-f5w6fw6q 163 30 in in IN cord-006870-f5w6fw6q 163 31 4 4 CD cord-006870-f5w6fw6q 163 32 of of IN cord-006870-f5w6fw6q 163 33 7 7 CD cord-006870-f5w6fw6q 163 34 . . . cord-006870-f5w6fw6q 164 1 No no DT cord-006870-f5w6fw6q 164 2 adverse adverse JJ cord-006870-f5w6fw6q 164 3 events event NNS cord-006870-f5w6fw6q 164 4 reported report VBN cord-006870-f5w6fw6q 164 5 , , , cord-006870-f5w6fw6q 164 6 such such JJ cord-006870-f5w6fw6q 164 7 as as IN cord-006870-f5w6fw6q 164 8 shock shock NN cord-006870-f5w6fw6q 164 9 , , , cord-006870-f5w6fw6q 164 10 cardiac cardiac JJ cord-006870-f5w6fw6q 164 11 arrest arrest NN cord-006870-f5w6fw6q 164 12 , , , cord-006870-f5w6fw6q 164 13 tissue tissue NN cord-006870-f5w6fw6q 164 14 or or CC cord-006870-f5w6fw6q 164 15 limb limb NN cord-006870-f5w6fw6q 164 16 injury injury NN cord-006870-f5w6fw6q 164 17 . . . cord-006870-f5w6fw6q 165 1 Preliminary preliminary JJ cord-006870-f5w6fw6q 165 2 data datum NNS cord-006870-f5w6fw6q 165 3 suggest suggest VBP cord-006870-f5w6fw6q 165 4 that that IN cord-006870-f5w6fw6q 165 5 during during IN cord-006870-f5w6fw6q 165 6 BH BH NNP cord-006870-f5w6fw6q 165 7 , , , cord-006870-f5w6fw6q 165 8 IO IO NNP cord-006870-f5w6fw6q 165 9 cannulation cannulation NN cord-006870-f5w6fw6q 165 10 results result NNS cord-006870-f5w6fw6q 165 11 in in IN cord-006870-f5w6fw6q 165 12 safe safe JJ cord-006870-f5w6fw6q 165 13 and and CC cord-006870-f5w6fw6q 165 14 timely timely JJ cord-006870-f5w6fw6q 165 15 23.4 23.4 CD cord-006870-f5w6fw6q 165 16 % % NN cord-006870-f5w6fw6q 165 17 administration administration NN cord-006870-f5w6fw6q 165 18 in in IN cord-006870-f5w6fw6q 165 19 patients patient NNS cord-006870-f5w6fw6q 165 20 with with IN cord-006870-f5w6fw6q 165 21 no no DT cord-006870-f5w6fw6q 165 22 central central JJ cord-006870-f5w6fw6q 165 23 access access NN cord-006870-f5w6fw6q 165 24 . . . cord-006870-f5w6fw6q 166 1 Additional additional JJ cord-006870-f5w6fw6q 166 2 safety safety NN cord-006870-f5w6fw6q 166 3 data datum NNS cord-006870-f5w6fw6q 166 4 is be VBZ cord-006870-f5w6fw6q 166 5 needed need VBN cord-006870-f5w6fw6q 166 6 , , , cord-006870-f5w6fw6q 166 7 particularly particularly RB cord-006870-f5w6fw6q 166 8 with with IN cord-006870-f5w6fw6q 166 9 regards regard NNS cord-006870-f5w6fw6q 166 10 to to IN cord-006870-f5w6fw6q 166 11 the the DT cord-006870-f5w6fw6q 166 12 potential potential NN cord-006870-f5w6fw6q 166 13 for for IN cord-006870-f5w6fw6q 166 14 myonecrosis myonecrosis NNP cord-006870-f5w6fw6q 166 15 . . . cord-006870-f5w6fw6q 167 1 However however RB cord-006870-f5w6fw6q 167 2 , , , cord-006870-f5w6fw6q 167 3 if if IN cord-006870-f5w6fw6q 167 4 safe safe JJ cord-006870-f5w6fw6q 167 5 , , , cord-006870-f5w6fw6q 167 6 IO IO NNP cord-006870-f5w6fw6q 167 7 cannulation cannulation NN cord-006870-f5w6fw6q 167 8 should should MD cord-006870-f5w6fw6q 167 9 replace replace VB cord-006870-f5w6fw6q 167 10 central central JJ cord-006870-f5w6fw6q 167 11 line line NN cord-006870-f5w6fw6q 167 12 placement placement NN cord-006870-f5w6fw6q 167 13 as as IN cord-006870-f5w6fw6q 167 14 the the DT cord-006870-f5w6fw6q 167 15 initial initial JJ cord-006870-f5w6fw6q 167 16 route route NN cord-006870-f5w6fw6q 167 17 of of IN cord-006870-f5w6fw6q 167 18 central central JJ cord-006870-f5w6fw6q 167 19 venous venous JJ cord-006870-f5w6fw6q 167 20 access access NN cord-006870-f5w6fw6q 167 21 during during IN cord-006870-f5w6fw6q 167 22 BH BH NNP cord-006870-f5w6fw6q 167 23 . . . cord-006870-f5w6fw6q 168 1 The the DT cord-006870-f5w6fw6q 168 2 pupillary pupillary JJ cord-006870-f5w6fw6q 168 3 light light JJ cord-006870-f5w6fw6q 168 4 reflex reflex NN cord-006870-f5w6fw6q 168 5 is be VBZ cord-006870-f5w6fw6q 168 6 associated associate VBN cord-006870-f5w6fw6q 168 7 with with IN cord-006870-f5w6fw6q 168 8 outcome outcome NN cord-006870-f5w6fw6q 168 9 after after IN cord-006870-f5w6fw6q 168 10 cardiac cardiac JJ cord-006870-f5w6fw6q 168 11 arrest arrest NN cord-006870-f5w6fw6q 168 12 as as IN cord-006870-f5w6fw6q 168 13 a a DT cord-006870-f5w6fw6q 168 14 dichotomous dichotomous JJ cord-006870-f5w6fw6q 168 15 variable variable NN cord-006870-f5w6fw6q 168 16 ( ( -LRB- cord-006870-f5w6fw6q 168 17 present present JJ cord-006870-f5w6fw6q 168 18 / / SYM cord-006870-f5w6fw6q 168 19 absent absent JJ cord-006870-f5w6fw6q 168 20 ) ) -RRB- cord-006870-f5w6fw6q 168 21 at at IN cord-006870-f5w6fw6q 168 22 various various JJ cord-006870-f5w6fw6q 168 23 time time NN cord-006870-f5w6fw6q 168 24 points point NNS cord-006870-f5w6fw6q 168 25 following follow VBG cord-006870-f5w6fw6q 168 26 resuscitation resuscitation NN cord-006870-f5w6fw6q 168 27 ( ( -LRB- cord-006870-f5w6fw6q 168 28 ROSC rosc NN cord-006870-f5w6fw6q 168 29 ) ) -RRB- cord-006870-f5w6fw6q 168 30 . . . cord-006870-f5w6fw6q 169 1 Infrared Infrared NNP cord-006870-f5w6fw6q 169 2 pupillometry pupillometry NNP cord-006870-f5w6fw6q 169 3 provides provide VBZ cord-006870-f5w6fw6q 169 4 quantitative quantitative JJ cord-006870-f5w6fw6q 169 5 measures measure NNS cord-006870-f5w6fw6q 169 6 including include VBG cord-006870-f5w6fw6q 169 7 pupil pupil NN cord-006870-f5w6fw6q 169 8 diameter diameter NN cord-006870-f5w6fw6q 169 9 ( ( -LRB- cord-006870-f5w6fw6q 169 10 PD PD NNP cord-006870-f5w6fw6q 169 11 ) ) -RRB- cord-006870-f5w6fw6q 169 12 , , , cord-006870-f5w6fw6q 169 13 and and CC cord-006870-f5w6fw6q 169 14 Neurological Neurological NNP cord-006870-f5w6fw6q 169 15 Pupil Pupil NNP cord-006870-f5w6fw6q 169 16 Index Index NNP cord-006870-f5w6fw6q 169 17 ( ( -LRB- cord-006870-f5w6fw6q 169 18 NPi NPi NNP cord-006870-f5w6fw6q 169 19 ) ) -RRB- cord-006870-f5w6fw6q 169 20 which which WDT cord-006870-f5w6fw6q 169 21 ranges range VBZ cord-006870-f5w6fw6q 169 22 from from IN cord-006870-f5w6fw6q 169 23 0 0 CD cord-006870-f5w6fw6q 169 24 ( ( -LRB- cord-006870-f5w6fw6q 169 25 nonreactive nonreactive JJ cord-006870-f5w6fw6q 169 26 ) ) -RRB- cord-006870-f5w6fw6q 169 27 to to IN cord-006870-f5w6fw6q 169 28 5 5 LS cord-006870-f5w6fw6q 169 29 ( ( -LRB- cord-006870-f5w6fw6q 169 30 brisk brisk JJ cord-006870-f5w6fw6q 169 31 ) ) -RRB- cord-006870-f5w6fw6q 169 32 and and CC cord-006870-f5w6fw6q 169 33 reflects reflect VBZ cord-006870-f5w6fw6q 169 34 velocity velocity NN cord-006870-f5w6fw6q 169 35 and and CC cord-006870-f5w6fw6q 169 36 degree degree NN cord-006870-f5w6fw6q 169 37 of of IN cord-006870-f5w6fw6q 169 38 pupil pupil NN cord-006870-f5w6fw6q 169 39 constriction constriction NN cord-006870-f5w6fw6q 169 40 in in IN cord-006870-f5w6fw6q 169 41 response response NN cord-006870-f5w6fw6q 169 42 to to IN cord-006870-f5w6fw6q 169 43 a a DT cord-006870-f5w6fw6q 169 44 standardized standardized JJ cord-006870-f5w6fw6q 169 45 light light JJ cord-006870-f5w6fw6q 169 46 stimulus stimulus NN cord-006870-f5w6fw6q 169 47 . . . cord-006870-f5w6fw6q 170 1 These these DT cord-006870-f5w6fw6q 170 2 measures measure NNS cord-006870-f5w6fw6q 170 3 may may MD cord-006870-f5w6fw6q 170 4 provide provide VB cord-006870-f5w6fw6q 170 5 early early JJ cord-006870-f5w6fw6q 170 6 prognostic prognostic JJ cord-006870-f5w6fw6q 170 7 information information NN cord-006870-f5w6fw6q 170 8 to to TO cord-006870-f5w6fw6q 170 9 guide guide VB cord-006870-f5w6fw6q 170 10 therapy therapy NN cord-006870-f5w6fw6q 170 11 . . . cord-006870-f5w6fw6q 171 1 Comatose comatose JJ cord-006870-f5w6fw6q 171 2 adult adult NN cord-006870-f5w6fw6q 171 3 survivors survivor NNS cord-006870-f5w6fw6q 171 4 of of IN cord-006870-f5w6fw6q 171 5 cardiac cardiac JJ cord-006870-f5w6fw6q 171 6 arrest arrest NN cord-006870-f5w6fw6q 171 7 treated treat VBN cord-006870-f5w6fw6q 171 8 with with IN cord-006870-f5w6fw6q 171 9 targeted target VBN cord-006870-f5w6fw6q 171 10 temperature temperature NN cord-006870-f5w6fw6q 171 11 management management NN cord-006870-f5w6fw6q 171 12 were be VBD cord-006870-f5w6fw6q 171 13 monitored monitor VBN cord-006870-f5w6fw6q 171 14 with with IN cord-006870-f5w6fw6q 171 15 the the DT cord-006870-f5w6fw6q 171 16 Neuroptics Neuroptics NNPS cord-006870-f5w6fw6q 171 17 NPi-200 NPi-200 NNP cord-006870-f5w6fw6q 171 18 pupillometer pupillometer NNP cord-006870-f5w6fw6q 171 19 . . . cord-006870-f5w6fw6q 172 1 Outcomes outcome NNS cord-006870-f5w6fw6q 172 2 were be VBD cord-006870-f5w6fw6q 172 3 defined define VBN cord-006870-f5w6fw6q 172 4 as as IN cord-006870-f5w6fw6q 172 5 good good JJ cord-006870-f5w6fw6q 172 6 ( ( -LRB- cord-006870-f5w6fw6q 172 7 GO go VB cord-006870-f5w6fw6q 172 8 ) ) -RRB- cord-006870-f5w6fw6q 173 1 if if IN cord-006870-f5w6fw6q 173 2 discharge discharge NN cord-006870-f5w6fw6q 173 3 Cerebral Cerebral NNP cord-006870-f5w6fw6q 173 4 Performance Performance NNP cord-006870-f5w6fw6q 173 5 Category Category NNP cord-006870-f5w6fw6q 173 6 score score NN cord-006870-f5w6fw6q 173 7 was be VBD cord-006870-f5w6fw6q 173 8 1 1 CD cord-006870-f5w6fw6q 173 9 - - SYM cord-006870-f5w6fw6q 173 10 2 2 CD cord-006870-f5w6fw6q 173 11 , , , cord-006870-f5w6fw6q 173 12 and and CC cord-006870-f5w6fw6q 173 13 poor poor JJ cord-006870-f5w6fw6q 173 14 ( ( -LRB- cord-006870-f5w6fw6q 173 15 PO po NN cord-006870-f5w6fw6q 173 16 ) ) -RRB- cord-006870-f5w6fw6q 174 1 if if IN cord-006870-f5w6fw6q 174 2 3 3 CD cord-006870-f5w6fw6q 174 3 - - SYM cord-006870-f5w6fw6q 174 4 5 5 CD cord-006870-f5w6fw6q 174 5 . . . cord-006870-f5w6fw6q 175 1 Data datum NNS cord-006870-f5w6fw6q 175 2 are be VBP cord-006870-f5w6fw6q 175 3 presented present VBN cord-006870-f5w6fw6q 175 4 as as IN cord-006870-f5w6fw6q 175 5 median median NN cord-006870-f5w6fw6q 175 6 ( ( -LRB- cord-006870-f5w6fw6q 175 7 IQR IQR NNP cord-006870-f5w6fw6q 175 8 ) ) -RRB- cord-006870-f5w6fw6q 175 9 . . . cord-006870-f5w6fw6q 176 1 Groups group NNS cord-006870-f5w6fw6q 176 2 were be VBD cord-006870-f5w6fw6q 176 3 compared compare VBN cord-006870-f5w6fw6q 176 4 using use VBG cord-006870-f5w6fw6q 176 5 non non JJ cord-006870-f5w6fw6q 176 6 - - JJ cord-006870-f5w6fw6q 176 7 parametric parametric JJ cord-006870-f5w6fw6q 176 8 statistical statistical JJ cord-006870-f5w6fw6q 176 9 tests test NNS cord-006870-f5w6fw6q 176 10 . . . cord-006870-f5w6fw6q 177 1 Fifty fifty CD cord-006870-f5w6fw6q 177 2 - - HYPH cord-006870-f5w6fw6q 177 3 one one CD cord-006870-f5w6fw6q 177 4 patients patient NNS cord-006870-f5w6fw6q 177 5 were be VBD cord-006870-f5w6fw6q 177 6 enrolled enrol VBN cord-006870-f5w6fw6q 177 7 ; ; : cord-006870-f5w6fw6q 177 8 the the DT cord-006870-f5w6fw6q 177 9 median median JJ cord-006870-f5w6fw6q 177 10 age age NN cord-006870-f5w6fw6q 177 11 was be VBD cord-006870-f5w6fw6q 177 12 57 57 CD cord-006870-f5w6fw6q 177 13 ( ( -LRB- cord-006870-f5w6fw6q 177 14 48.5 48.5 CD cord-006870-f5w6fw6q 177 15 - - HYPH cord-006870-f5w6fw6q 177 16 68.5 68.5 CD cord-006870-f5w6fw6q 177 17 ) ) -RRB- cord-006870-f5w6fw6q 177 18 , , , cord-006870-f5w6fw6q 177 19 and and CC cord-006870-f5w6fw6q 177 20 33 33 CD cord-006870-f5w6fw6q 177 21 ( ( -LRB- cord-006870-f5w6fw6q 177 22 65 65 CD cord-006870-f5w6fw6q 177 23 % % NN cord-006870-f5w6fw6q 177 24 ) ) -RRB- cord-006870-f5w6fw6q 177 25 were be VBD cord-006870-f5w6fw6q 177 26 male male JJ cord-006870-f5w6fw6q 177 27 . . . cord-006870-f5w6fw6q 178 1 Initial initial JJ cord-006870-f5w6fw6q 178 2 rhythm rhythm NN cord-006870-f5w6fw6q 178 3 was be VBD cord-006870-f5w6fw6q 178 4 VT VT NNP cord-006870-f5w6fw6q 178 5 / / SYM cord-006870-f5w6fw6q 178 6 VF VF NNP cord-006870-f5w6fw6q 178 7 in in IN cord-006870-f5w6fw6q 178 8 55 55 CD cord-006870-f5w6fw6q 178 9 % % NN cord-006870-f5w6fw6q 178 10 , , , cord-006870-f5w6fw6q 178 11 asystole asystole NN cord-006870-f5w6fw6q 178 12 in in IN cord-006870-f5w6fw6q 178 13 23 23 CD cord-006870-f5w6fw6q 178 14 % % NN cord-006870-f5w6fw6q 178 15 , , , cord-006870-f5w6fw6q 178 16 and and CC cord-006870-f5w6fw6q 178 17 PEA pea NN cord-006870-f5w6fw6q 178 18 in in IN cord-006870-f5w6fw6q 178 19 20 20 CD cord-006870-f5w6fw6q 178 20 % % NN cord-006870-f5w6fw6q 178 21 . . . cord-006870-f5w6fw6q 179 1 Outcome outcome NN cord-006870-f5w6fw6q 179 2 was be VBD cord-006870-f5w6fw6q 179 3 good good JJ cord-006870-f5w6fw6q 179 4 in in IN cord-006870-f5w6fw6q 179 5 16 16 CD cord-006870-f5w6fw6q 179 6 ( ( -LRB- cord-006870-f5w6fw6q 179 7 31 31 CD cord-006870-f5w6fw6q 179 8 % % NN cord-006870-f5w6fw6q 179 9 ) ) -RRB- cord-006870-f5w6fw6q 179 10 patients patient NNS cord-006870-f5w6fw6q 179 11 . . . cord-006870-f5w6fw6q 180 1 The the DT cord-006870-f5w6fw6q 180 2 initial initial JJ cord-006870-f5w6fw6q 180 3 PD PD NNP cord-006870-f5w6fw6q 180 4 did do VBD cord-006870-f5w6fw6q 180 5 not not RB cord-006870-f5w6fw6q 180 6 differ differ VB cord-006870-f5w6fw6q 180 7 between between IN cord-006870-f5w6fw6q 180 8 outcome outcome NN cord-006870-f5w6fw6q 180 9 groups group NNS cord-006870-f5w6fw6q 180 10 [ [ -LRB- cord-006870-f5w6fw6q 181 1 3.1 3.1 LS cord-006870-f5w6fw6q 181 2 ( ( -LRB- cord-006870-f5w6fw6q 181 3 2 2 CD cord-006870-f5w6fw6q 181 4 - - SYM cord-006870-f5w6fw6q 181 5 4.7 4.7 CD cord-006870-f5w6fw6q 181 6 ) ) -RRB- cord-006870-f5w6fw6q 181 7 PO PO NNP cord-006870-f5w6fw6q 181 8 vs vs IN cord-006870-f5w6fw6q 181 9 3.0 3.0 CD cord-006870-f5w6fw6q 181 10 ( ( -LRB- cord-006870-f5w6fw6q 181 11 2 2 CD cord-006870-f5w6fw6q 181 12 - - SYM cord-006870-f5w6fw6q 181 13 4.2 4.2 CD cord-006870-f5w6fw6q 181 14 ) ) -RRB- cord-006870-f5w6fw6q 181 15 GO go VB cord-006870-f5w6fw6q 181 16 ] ] -RRB- cord-006870-f5w6fw6q 181 17 . . . cord-006870-f5w6fw6q 182 1 The the DT cord-006870-f5w6fw6q 182 2 initial initial JJ cord-006870-f5w6fw6q 182 3 NPi NPi NNS cord-006870-f5w6fw6q 182 4 was be VBD cord-006870-f5w6fw6q 182 5 lower low JJR cord-006870-f5w6fw6q 182 6 in in IN cord-006870-f5w6fw6q 182 7 poor poor JJ cord-006870-f5w6fw6q 182 8 outcome outcome NN cord-006870-f5w6fw6q 182 9 patients patient NNS cord-006870-f5w6fw6q 182 10 [ [ -LRB- cord-006870-f5w6fw6q 182 11 3.3 3.3 CD cord-006870-f5w6fw6q 182 12 ( ( -LRB- cord-006870-f5w6fw6q 182 13 1.5 1.5 CD cord-006870-f5w6fw6q 182 14 - - SYM cord-006870-f5w6fw6q 182 15 4 4 CD cord-006870-f5w6fw6q 182 16 ) ) -RRB- cord-006870-f5w6fw6q 182 17 vs vs IN cord-006870-f5w6fw6q 182 18 3.9 3.9 CD cord-006870-f5w6fw6q 182 19 ( ( -LRB- cord-006870-f5w6fw6q 182 20 2.4 2.4 CD cord-006870-f5w6fw6q 182 21 - - SYM cord-006870-f5w6fw6q 182 22 4.2 4.2 CD cord-006870-f5w6fw6q 182 23 ) ) -RRB- cord-006870-f5w6fw6q 182 24 GO go VB cord-006870-f5w6fw6q 182 25 , , , cord-006870-f5w6fw6q 182 26 p=0.005 p=0.005 NNP cord-006870-f5w6fw6q 182 27 ] ] -RRB- cord-006870-f5w6fw6q 183 1 measured measure VBN cord-006870-f5w6fw6q 184 1 4.5 4.5 CD cord-006870-f5w6fw6q 184 2 ( ( -LRB- cord-006870-f5w6fw6q 184 3 3.4 3.4 CD cord-006870-f5w6fw6q 184 4 - - SYM cord-006870-f5w6fw6q 184 5 6.3 6.3 CD cord-006870-f5w6fw6q 184 6 ) ) -RRB- cord-006870-f5w6fw6q 184 7 hours hour NNS cord-006870-f5w6fw6q 184 8 after after IN cord-006870-f5w6fw6q 184 9 ROSC rosc NN cord-006870-f5w6fw6q 184 10 . . . cord-006870-f5w6fw6q 185 1 NPi NPi NNP cord-006870-f5w6fw6q 185 2 dropped drop VBD cord-006870-f5w6fw6q 185 3 below below IN cord-006870-f5w6fw6q 185 4 3 3 CD cord-006870-f5w6fw6q 185 5 in in IN cord-006870-f5w6fw6q 185 6 more more JJR cord-006870-f5w6fw6q 185 7 poor poor JJ cord-006870-f5w6fw6q 185 8 outcome outcome NN cord-006870-f5w6fw6q 185 9 patients patient NNS cord-006870-f5w6fw6q 185 10 [ [ -LRB- cord-006870-f5w6fw6q 185 11 27(77 27(77 CD cord-006870-f5w6fw6q 185 12 % % NN cord-006870-f5w6fw6q 185 13 ) ) -RRB- cord-006870-f5w6fw6q 185 14 vs vs IN cord-006870-f5w6fw6q 185 15 6(37.5 6(37.5 CD cord-006870-f5w6fw6q 185 16 % % NN cord-006870-f5w6fw6q 185 17 ) ) -RRB- cord-006870-f5w6fw6q 185 18 GO go VB cord-006870-f5w6fw6q 185 19 , , , cord-006870-f5w6fw6q 185 20 p=0 p=0 VBP cord-006870-f5w6fw6q 185 21 .015 .015 CD cord-006870-f5w6fw6q 185 22 ] ] -RRB- cord-006870-f5w6fw6q 185 23 , , , cord-006870-f5w6fw6q 185 24 and and CC cord-006870-f5w6fw6q 185 25 to to IN cord-006870-f5w6fw6q 185 26 zero zero CD cord-006870-f5w6fw6q 185 27 in in IN cord-006870-f5w6fw6q 185 28 18(51 18(51 CD cord-006870-f5w6fw6q 185 29 % % NN cord-006870-f5w6fw6q 185 30 ) ) -RRB- cord-006870-f5w6fw6q 185 31 poor poor JJ cord-006870-f5w6fw6q 185 32 vs vs IN cord-006870-f5w6fw6q 185 33 1(6 1(6 CD cord-006870-f5w6fw6q 185 34 % % NN cord-006870-f5w6fw6q 185 35 ) ) -RRB- cord-006870-f5w6fw6q 185 36 good good JJ cord-006870-f5w6fw6q 185 37 outcome outcome NN cord-006870-f5w6fw6q 185 38 patients patient NNS cord-006870-f5w6fw6q 185 39 ( ( -LRB- cord-006870-f5w6fw6q 185 40 p=0.005 p=0.005 NNP cord-006870-f5w6fw6q 185 41 ) ) -RRB- cord-006870-f5w6fw6q 185 42 . . . cord-006870-f5w6fw6q 186 1 Receiver receiver NN cord-006870-f5w6fw6q 186 2 operator operator NN cord-006870-f5w6fw6q 186 3 characteristic characteristic JJ cord-006870-f5w6fw6q 186 4 curves curve NNS cord-006870-f5w6fw6q 186 5 confirmed confirm VBD cord-006870-f5w6fw6q 186 6 that that IN cord-006870-f5w6fw6q 186 7 initial initial JJ cord-006870-f5w6fw6q 186 8 NPi NPi NNS cord-006870-f5w6fw6q 186 9 predicted predict VBD cord-006870-f5w6fw6q 186 10 poor poor JJ cord-006870-f5w6fw6q 186 11 outcome outcome NN cord-006870-f5w6fw6q 186 12 better well RBR cord-006870-f5w6fw6q 186 13 than than IN cord-006870-f5w6fw6q 186 14 pupil pupil NN cord-006870-f5w6fw6q 186 15 diameter diameter NN cord-006870-f5w6fw6q 186 16 ( ( -LRB- cord-006870-f5w6fw6q 186 17 AUC AUC NNP cord-006870-f5w6fw6q 186 18 0.78 0.78 CD cord-006870-f5w6fw6q 186 19 vs vs IN cord-006870-f5w6fw6q 186 20 0.61 0.61 CD cord-006870-f5w6fw6q 186 21 , , , cord-006870-f5w6fw6q 186 22 p=0.016 p=0.016 RB cord-006870-f5w6fw6q 186 23 ) ) -RRB- cord-006870-f5w6fw6q 186 24 . . . cord-006870-f5w6fw6q 187 1 A a DT cord-006870-f5w6fw6q 187 2 low low JJ cord-006870-f5w6fw6q 187 3 Neurological Neurological NNP cord-006870-f5w6fw6q 187 4 Pupil Pupil NNP cord-006870-f5w6fw6q 187 5 index index NN cord-006870-f5w6fw6q 187 6 predicted predict VBD cord-006870-f5w6fw6q 187 7 poor poor JJ cord-006870-f5w6fw6q 187 8 outcome outcome NN cord-006870-f5w6fw6q 187 9 4 4 CD cord-006870-f5w6fw6q 187 10 - - SYM cord-006870-f5w6fw6q 187 11 6 6 CD cord-006870-f5w6fw6q 187 12 hours hour NNS cord-006870-f5w6fw6q 187 13 after after IN cord-006870-f5w6fw6q 187 14 resuscitation resuscitation NN cord-006870-f5w6fw6q 187 15 from from IN cord-006870-f5w6fw6q 187 16 cardiac cardiac JJ cord-006870-f5w6fw6q 187 17 arrest arrest NN cord-006870-f5w6fw6q 187 18 , , , cord-006870-f5w6fw6q 187 19 and and CC cord-006870-f5w6fw6q 187 20 dropped drop VBD cord-006870-f5w6fw6q 187 21 to to IN cord-006870-f5w6fw6q 187 22 abnormal abnormal JJ cord-006870-f5w6fw6q 187 23 levels level NNS cord-006870-f5w6fw6q 187 24 ( ( -LRB- cord-006870-f5w6fw6q 187 25 <3 <3 NN cord-006870-f5w6fw6q 187 26 ) ) -RRB- cord-006870-f5w6fw6q 187 27 and and CC cord-006870-f5w6fw6q 187 28 to to IN cord-006870-f5w6fw6q 187 29 zero zero CD cord-006870-f5w6fw6q 187 30 ( ( -LRB- cord-006870-f5w6fw6q 187 31 reflecting reflect VBG cord-006870-f5w6fw6q 187 32 a a DT cord-006870-f5w6fw6q 187 33 non non JJ cord-006870-f5w6fw6q 187 34 - - JJ cord-006870-f5w6fw6q 187 35 reactive reactive JJ cord-006870-f5w6fw6q 187 36 pupil pupil NN cord-006870-f5w6fw6q 187 37 ) ) -RRB- cord-006870-f5w6fw6q 187 38 more more RBR cord-006870-f5w6fw6q 187 39 often often RB cord-006870-f5w6fw6q 187 40 in in IN cord-006870-f5w6fw6q 187 41 patients patient NNS cord-006870-f5w6fw6q 187 42 with with IN cord-006870-f5w6fw6q 187 43 poor poor JJ cord-006870-f5w6fw6q 187 44 outcomes outcome NNS cord-006870-f5w6fw6q 187 45 . . . cord-006870-f5w6fw6q 188 1 Additional additional JJ cord-006870-f5w6fw6q 188 2 research research NN cord-006870-f5w6fw6q 188 3 is be VBZ cord-006870-f5w6fw6q 188 4 needed need VBN cord-006870-f5w6fw6q 188 5 to to TO cord-006870-f5w6fw6q 188 6 define define VB cord-006870-f5w6fw6q 188 7 potential potential JJ cord-006870-f5w6fw6q 188 8 confounders confounder NNS cord-006870-f5w6fw6q 188 9 , , , cord-006870-f5w6fw6q 188 10 optimal optimal JJ cord-006870-f5w6fw6q 188 11 timing timing NN cord-006870-f5w6fw6q 188 12 , , , cord-006870-f5w6fw6q 188 13 and and CC cord-006870-f5w6fw6q 188 14 thresholds threshold NNS cord-006870-f5w6fw6q 188 15 for for IN cord-006870-f5w6fw6q 188 16 different different JJ cord-006870-f5w6fw6q 188 17 levels level NNS cord-006870-f5w6fw6q 188 18 of of IN cord-006870-f5w6fw6q 188 19 neurological neurological JJ cord-006870-f5w6fw6q 188 20 risk risk NN cord-006870-f5w6fw6q 188 21 with with IN cord-006870-f5w6fw6q 188 22 pupillometry pupillometry NNP cord-006870-f5w6fw6q 188 23 . . . cord-006870-f5w6fw6q 189 1 Prediction prediction NN cord-006870-f5w6fw6q 189 2 of of IN cord-006870-f5w6fw6q 189 3 death death NN cord-006870-f5w6fw6q 189 4 in in IN cord-006870-f5w6fw6q 189 5 a a DT cord-006870-f5w6fw6q 189 6 timely timely JJ cord-006870-f5w6fw6q 189 7 manner manner NN cord-006870-f5w6fw6q 189 8 after after IN cord-006870-f5w6fw6q 189 9 withdrawal withdrawal NN cord-006870-f5w6fw6q 189 10 of of IN cord-006870-f5w6fw6q 189 11 life life NN cord-006870-f5w6fw6q 189 12 support support NN cord-006870-f5w6fw6q 189 13 ( ( -LRB- cord-006870-f5w6fw6q 189 14 WLS WLS NNP cord-006870-f5w6fw6q 189 15 ) ) -RRB- cord-006870-f5w6fw6q 189 16 is be VBZ cord-006870-f5w6fw6q 189 17 essential essential JJ cord-006870-f5w6fw6q 189 18 during during IN cord-006870-f5w6fw6q 189 19 organ organ NN cord-006870-f5w6fw6q 189 20 donation donation NN cord-006870-f5w6fw6q 189 21 after after IN cord-006870-f5w6fw6q 189 22 cardiac cardiac JJ cord-006870-f5w6fw6q 189 23 death death NN cord-006870-f5w6fw6q 189 24 ( ( -LRB- cord-006870-f5w6fw6q 189 25 DCD DCD NNP cord-006870-f5w6fw6q 189 26 ) ) -RRB- cord-006870-f5w6fw6q 189 27 . . . cord-006870-f5w6fw6q 190 1 We -PRON- PRP cord-006870-f5w6fw6q 190 2 aimed aim VBD cord-006870-f5w6fw6q 190 3 to to TO cord-006870-f5w6fw6q 190 4 develop develop VB cord-006870-f5w6fw6q 190 5 a a DT cord-006870-f5w6fw6q 190 6 modified modify VBN cord-006870-f5w6fw6q 190 7 version version NN cord-006870-f5w6fw6q 190 8 of of IN cord-006870-f5w6fw6q 190 9 the the DT cord-006870-f5w6fw6q 190 10 recently recently RB cord-006870-f5w6fw6q 190 11 develop develop VB cord-006870-f5w6fw6q 190 12 DCD DCD NNP cord-006870-f5w6fw6q 190 13 - - HYPH cord-006870-f5w6fw6q 190 14 N N NNP cord-006870-f5w6fw6q 190 15 score score NN cord-006870-f5w6fw6q 190 16 to to TO cord-006870-f5w6fw6q 190 17 improve improve VB cord-006870-f5w6fw6q 190 18 the the DT cord-006870-f5w6fw6q 190 19 specificity specificity NN cord-006870-f5w6fw6q 190 20 of of IN cord-006870-f5w6fw6q 190 21 prediction prediction NN cord-006870-f5w6fw6q 190 22 and and CC cord-006870-f5w6fw6q 190 23 test test VB cord-006870-f5w6fw6q 190 24 it -PRON- PRP cord-006870-f5w6fw6q 190 25 in in IN cord-006870-f5w6fw6q 190 26 a a DT cord-006870-f5w6fw6q 190 27 specific specific JJ cord-006870-f5w6fw6q 190 28 group group NN cord-006870-f5w6fw6q 190 29 of of IN cord-006870-f5w6fw6q 190 30 patients patient NNS cord-006870-f5w6fw6q 190 31 with with IN cord-006870-f5w6fw6q 190 32 catastrophic catastrophic JJ cord-006870-f5w6fw6q 190 33 brain brain NN cord-006870-f5w6fw6q 190 34 injuries injury NNS cord-006870-f5w6fw6q 190 35 referred refer VBN cord-006870-f5w6fw6q 190 36 for for IN cord-006870-f5w6fw6q 190 37 DCD DCD NNP cord-006870-f5w6fw6q 190 38 . . . cord-006870-f5w6fw6q 191 1 We -PRON- PRP cord-006870-f5w6fw6q 191 2 analyzed analyze VBD cord-006870-f5w6fw6q 191 3 prospectively prospectively RB cord-006870-f5w6fw6q 191 4 collected collect VBN cord-006870-f5w6fw6q 191 5 data datum NNS cord-006870-f5w6fw6q 191 6 by by IN cord-006870-f5w6fw6q 191 7 our -PRON- PRP$ cord-006870-f5w6fw6q 191 8 local local JJ cord-006870-f5w6fw6q 191 9 organ organ NN cord-006870-f5w6fw6q 191 10 procurement procurement NN cord-006870-f5w6fw6q 191 11 agency agency NN cord-006870-f5w6fw6q 191 12 on on IN cord-006870-f5w6fw6q 191 13 all all DT cord-006870-f5w6fw6q 191 14 consecutive consecutive JJ cord-006870-f5w6fw6q 191 15 adults adult NNS cord-006870-f5w6fw6q 191 16 with with IN cord-006870-f5w6fw6q 191 17 severe severe JJ cord-006870-f5w6fw6q 191 18 neurological neurological JJ cord-006870-f5w6fw6q 191 19 injury injury NN cord-006870-f5w6fw6q 191 20 evaluated evaluate VBN cord-006870-f5w6fw6q 191 21 for for IN cord-006870-f5w6fw6q 191 22 DCD DCD NNP cord-006870-f5w6fw6q 191 23 across across IN cord-006870-f5w6fw6q 191 24 18 18 CD cord-006870-f5w6fw6q 191 25 centers center NNS cord-006870-f5w6fw6q 191 26 in in IN cord-006870-f5w6fw6q 191 27 the the DT cord-006870-f5w6fw6q 191 28 USA USA NNP cord-006870-f5w6fw6q 191 29 from from IN cord-006870-f5w6fw6q 191 30 March March NNP cord-006870-f5w6fw6q 191 31 2015 2015 CD cord-006870-f5w6fw6q 191 32 to to IN cord-006870-f5w6fw6q 191 33 May May NNP cord-006870-f5w6fw6q 191 34 2017 2017 CD cord-006870-f5w6fw6q 191 35 . . . cord-006870-f5w6fw6q 192 1 We -PRON- PRP cord-006870-f5w6fw6q 192 2 analyzed analyze VBD cord-006870-f5w6fw6q 192 3 three three CD cord-006870-f5w6fw6q 192 4 variables variable NNS cord-006870-f5w6fw6q 192 5 used use VBN cord-006870-f5w6fw6q 192 6 in in IN cord-006870-f5w6fw6q 192 7 the the DT cord-006870-f5w6fw6q 192 8 DCD DCD NNP cord-006870-f5w6fw6q 192 9 - - HYPH cord-006870-f5w6fw6q 192 10 N N NNP cord-006870-f5w6fw6q 192 11 score score NN cord-006870-f5w6fw6q 192 12 ( ( -LRB- cord-006870-f5w6fw6q 192 13 corneal corneal JJ cord-006870-f5w6fw6q 192 14 reflex reflex NN cord-006870-f5w6fw6q 192 15 , , , cord-006870-f5w6fw6q 192 16 cough cough NN cord-006870-f5w6fw6q 192 17 reflex reflex NN cord-006870-f5w6fw6q 192 18 and and CC cord-006870-f5w6fw6q 192 19 oxygenation oxygenation NN cord-006870-f5w6fw6q 192 20 index index NN cord-006870-f5w6fw6q 192 21 ) ) -RRB- cord-006870-f5w6fw6q 192 22 and and CC cord-006870-f5w6fw6q 192 23 substituted substitute VBD cord-006870-f5w6fw6q 192 24 the the DT cord-006870-f5w6fw6q 192 25 fourth fourth JJ cord-006870-f5w6fw6q 192 26 variable variable NN cord-006870-f5w6fw6q 192 27 for for IN cord-006870-f5w6fw6q 192 28 vasopressor vasopressor NN cord-006870-f5w6fw6q 192 29 support support NN cord-006870-f5w6fw6q 192 30 . . . cord-006870-f5w6fw6q 193 1 A a DT cord-006870-f5w6fw6q 193 2 total total NN cord-006870-f5w6fw6q 193 3 of of IN cord-006870-f5w6fw6q 193 4 278 278 CD cord-006870-f5w6fw6q 193 5 patients patient NNS cord-006870-f5w6fw6q 193 6 , , , cord-006870-f5w6fw6q 193 7 mean mean VB cord-006870-f5w6fw6q 193 8 age age NN cord-006870-f5w6fw6q 193 9 50 50 CD cord-006870-f5w6fw6q 194 1 ( ( -LRB- cord-006870-f5w6fw6q 194 2 SD±13 SD±13 NNP cord-006870-f5w6fw6q 194 3 ) ) -RRB- cord-006870-f5w6fw6q 194 4 years year NNS cord-006870-f5w6fw6q 194 5 were be VBD cord-006870-f5w6fw6q 194 6 included include VBN cord-006870-f5w6fw6q 194 7 in in IN cord-006870-f5w6fw6q 194 8 the the DT cord-006870-f5w6fw6q 194 9 final final JJ cord-006870-f5w6fw6q 194 10 analysis analysis NN cord-006870-f5w6fw6q 194 11 . . . cord-006870-f5w6fw6q 195 1 Anoxic Anoxic NNP cord-006870-f5w6fw6q 195 2 brain brain NN cord-006870-f5w6fw6q 195 3 injury injury NN cord-006870-f5w6fw6q 195 4 was be VBD cord-006870-f5w6fw6q 195 5 the the DT cord-006870-f5w6fw6q 195 6 most most RBS cord-006870-f5w6fw6q 195 7 common common JJ cord-006870-f5w6fw6q 195 8 cause cause NN cord-006870-f5w6fw6q 195 9 of of IN cord-006870-f5w6fw6q 195 10 death death NN cord-006870-f5w6fw6q 195 11 ( ( -LRB- cord-006870-f5w6fw6q 195 12 55 55 CD cord-006870-f5w6fw6q 195 13 % % NN cord-006870-f5w6fw6q 195 14 ) ) -RRB- cord-006870-f5w6fw6q 195 15 followed follow VBN cord-006870-f5w6fw6q 195 16 by by IN cord-006870-f5w6fw6q 195 17 stroke stroke NN cord-006870-f5w6fw6q 195 18 ( ( -LRB- cord-006870-f5w6fw6q 195 19 27 27 CD cord-006870-f5w6fw6q 195 20 % % NN cord-006870-f5w6fw6q 195 21 ) ) -RRB- cord-006870-f5w6fw6q 195 22 . . . cord-006870-f5w6fw6q 196 1 In in IN cord-006870-f5w6fw6q 196 2 multivariate multivariate JJ cord-006870-f5w6fw6q 196 3 logistic logistic JJ cord-006870-f5w6fw6q 196 4 regression regression NN cord-006870-f5w6fw6q 196 5 analysis analysis NN cord-006870-f5w6fw6q 196 6 adjusted adjust VBN cord-006870-f5w6fw6q 196 7 for for IN cord-006870-f5w6fw6q 196 8 age age NN cord-006870-f5w6fw6q 196 9 and and CC cord-006870-f5w6fw6q 196 10 cause cause NN cord-006870-f5w6fw6q 196 11 of of IN cord-006870-f5w6fw6q 196 12 death death NN cord-006870-f5w6fw6q 196 13 , , , cord-006870-f5w6fw6q 196 14 absent absent JJ cord-006870-f5w6fw6q 196 15 corneal corneal JJ cord-006870-f5w6fw6q 196 16 reflex reflex NN cord-006870-f5w6fw6q 196 17 ( ( -LRB- cord-006870-f5w6fw6q 196 18 OR or CC cord-006870-f5w6fw6q 196 19 3.2 3.2 CD cord-006870-f5w6fw6q 196 20 , , , cord-006870-f5w6fw6q 197 1 95 95 CD cord-006870-f5w6fw6q 197 2 % % NN cord-006870-f5w6fw6q 197 3 CI CI NNP cord-006870-f5w6fw6q 197 4 1.6 1.6 CD cord-006870-f5w6fw6q 197 5 to to IN cord-006870-f5w6fw6q 197 6 6.0 6.0 CD cord-006870-f5w6fw6q 197 7 , , , cord-006870-f5w6fw6q 197 8 p p NN cord-006870-f5w6fw6q 197 9 = = SYM cord-006870-f5w6fw6q 197 10 0.0005 0.0005 CD cord-006870-f5w6fw6q 197 11 , , , cord-006870-f5w6fw6q 197 12 2 2 CD cord-006870-f5w6fw6q 197 13 points point NNS cord-006870-f5w6fw6q 197 14 ) ) -RRB- cord-006870-f5w6fw6q 197 15 , , , cord-006870-f5w6fw6q 197 16 absent absent JJ cord-006870-f5w6fw6q 197 17 cough cough NN cord-006870-f5w6fw6q 197 18 reflex reflex NN cord-006870-f5w6fw6q 197 19 ( ( -LRB- cord-006870-f5w6fw6q 197 20 OR or CC cord-006870-f5w6fw6q 197 21 2.2 2.2 CD cord-006870-f5w6fw6q 197 22 , , , cord-006870-f5w6fw6q 197 23 95 95 CD cord-006870-f5w6fw6q 197 24 % % NN cord-006870-f5w6fw6q 197 25 CI CI NNP cord-006870-f5w6fw6q 197 26 1.1 1.1 CD cord-006870-f5w6fw6q 197 27 to to IN cord-006870-f5w6fw6q 197 28 4.2 4.2 CD cord-006870-f5w6fw6q 197 29 , , , cord-006870-f5w6fw6q 197 30 p p NN cord-006870-f5w6fw6q 197 31 = = SYM cord-006870-f5w6fw6q 197 32 0.02 0.02 CD cord-006870-f5w6fw6q 197 33 , , , cord-006870-f5w6fw6q 197 34 1 1 CD cord-006870-f5w6fw6q 197 35 point point NN cord-006870-f5w6fw6q 197 36 ) ) -RRB- cord-006870-f5w6fw6q 198 1 , , , cord-006870-f5w6fw6q 198 2 vasopressor vasopressor NN cord-006870-f5w6fw6q 198 3 support support NN cord-006870-f5w6fw6q 198 4 at at IN cord-006870-f5w6fw6q 198 5 high high JJ cord-006870-f5w6fw6q 198 6 doses dose NNS cord-006870-f5w6fw6q 198 7 ( ( -LRB- cord-006870-f5w6fw6q 198 8 OR or CC cord-006870-f5w6fw6q 198 9 4.9 4.9 CD cord-006870-f5w6fw6q 198 10 , , , cord-006870-f5w6fw6q 198 11 95 95 CD cord-006870-f5w6fw6q 198 12 % % NN cord-006870-f5w6fw6q 198 13 CI CI NNP cord-006870-f5w6fw6q 198 14 2.3 2.3 CD cord-006870-f5w6fw6q 198 15 to to IN cord-006870-f5w6fw6q 198 16 10.5 10.5 CD cord-006870-f5w6fw6q 198 17 , , , cord-006870-f5w6fw6q 198 18 p p NN cord-006870-f5w6fw6q 198 19 < < XX cord-006870-f5w6fw6q 198 20 0.0001 0.0001 CD cord-006870-f5w6fw6q 198 21 , , , cord-006870-f5w6fw6q 198 22 2 2 CD cord-006870-f5w6fw6q 198 23 points point NNS cord-006870-f5w6fw6q 198 24 ) ) -RRB- cord-006870-f5w6fw6q 198 25 and and CC cord-006870-f5w6fw6q 198 26 O2 O2 NNP cord-006870-f5w6fw6q 198 27 Ind Ind NNP cord-006870-f5w6fw6q 198 28 CI CI NNP cord-006870-f5w6fw6q 198 29 1.6 1.6 CD cord-006870-f5w6fw6q 198 30 to to IN cord-006870-f5w6fw6q 198 31 5.5 5.5 CD cord-006870-f5w6fw6q 198 32 , , , cord-006870-f5w6fw6q 198 33 p p NN cord-006870-f5w6fw6q 198 34 = = SYM cord-006870-f5w6fw6q 198 35 0.0005 0.0005 CD cord-006870-f5w6fw6q 198 36 , , , cord-006870-f5w6fw6q 198 37 2 2 CD cord-006870-f5w6fw6q 198 38 points point NNS cord-006870-f5w6fw6q 198 39 ) ) -RRB- cord-006870-f5w6fw6q 198 40 were be VBD cord-006870-f5w6fw6q 198 41 associated associate VBN cord-006870-f5w6fw6q 198 42 with with IN cord-006870-f5w6fw6q 198 43 the the DT cord-006870-f5w6fw6q 198 44 likelihood likelihood NN cord-006870-f5w6fw6q 198 45 of of IN cord-006870-f5w6fw6q 198 46 death death NN cord-006870-f5w6fw6q 198 47 within within IN cord-006870-f5w6fw6q 198 48 60 60 CD cord-006870-f5w6fw6q 198 49 minutes minute NNS cord-006870-f5w6fw6q 198 50 of of IN cord-006870-f5w6fw6q 198 51 specificity specificity NN cord-006870-f5w6fw6q 198 52 83 83 CD cord-006870-f5w6fw6q 198 53 % % NN cord-006870-f5w6fw6q 198 54 and and CC cord-006870-f5w6fw6q 198 55 AUC AUC NNP cord-006870-f5w6fw6q 198 56 0.81 0.81 CD cord-006870-f5w6fw6q 198 57 . . . cord-006870-f5w6fw6q 199 1 The the DT cord-006870-f5w6fw6q 199 2 modified modify VBN cord-006870-f5w6fw6q 199 3 DCD DCD NNP cord-006870-f5w6fw6q 199 4 - - HYPH cord-006870-f5w6fw6q 199 5 N N NNP cord-006870-f5w6fw6q 199 6 score score NN cord-006870-f5w6fw6q 199 7 has have VBZ cord-006870-f5w6fw6q 199 8 a a DT cord-006870-f5w6fw6q 199 9 greater great JJR cord-006870-f5w6fw6q 199 10 specificity specificity NN cord-006870-f5w6fw6q 199 11 in in IN cord-006870-f5w6fw6q 199 12 predicting predict VBG cord-006870-f5w6fw6q 199 13 death death NN cord-006870-f5w6fw6q 199 14 within within IN cord-006870-f5w6fw6q 199 15 60 60 CD cord-006870-f5w6fw6q 199 16 minutes minute NNS cord-006870-f5w6fw6q 199 17 of of IN cord-006870-f5w6fw6q 199 18 WLS WLS NNP cord-006870-f5w6fw6q 199 19 and and CC cord-006870-f5w6fw6q 199 20 is be VBZ cord-006870-f5w6fw6q 199 21 developed develop VBN cord-006870-f5w6fw6q 199 22 specifically specifically RB cord-006870-f5w6fw6q 199 23 from from IN cord-006870-f5w6fw6q 199 24 a a DT cord-006870-f5w6fw6q 199 25 cohort cohort NN cord-006870-f5w6fw6q 199 26 of of IN cord-006870-f5w6fw6q 199 27 patients patient NNS cord-006870-f5w6fw6q 199 28 evaluated evaluate VBN cord-006870-f5w6fw6q 199 29 for for IN cord-006870-f5w6fw6q 199 30 DCD DCD NNP cord-006870-f5w6fw6q 199 31 . . . cord-006870-f5w6fw6q 200 1 Future future JJ cord-006870-f5w6fw6q 200 2 prospective prospective JJ cord-006870-f5w6fw6q 200 3 studies study NNS cord-006870-f5w6fw6q 200 4 are be VBP cord-006870-f5w6fw6q 200 5 needed need VBN cord-006870-f5w6fw6q 200 6 for for IN cord-006870-f5w6fw6q 200 7 further further JJ cord-006870-f5w6fw6q 200 8 validation validation NN cord-006870-f5w6fw6q 200 9 of of IN cord-006870-f5w6fw6q 200 10 this this DT cord-006870-f5w6fw6q 200 11 scoring scoring NN cord-006870-f5w6fw6q 200 12 system system NN cord-006870-f5w6fw6q 200 13 . . . cord-006870-f5w6fw6q 201 1 Significant significant JJ cord-006870-f5w6fw6q 201 2 number number NN cord-006870-f5w6fw6q 201 3 of of IN cord-006870-f5w6fw6q 201 4 the the DT cord-006870-f5w6fw6q 201 5 patients patient NNS cord-006870-f5w6fw6q 201 6 with with IN cord-006870-f5w6fw6q 201 7 anoxic anoxic JJ cord-006870-f5w6fw6q 201 8 brain brain NN cord-006870-f5w6fw6q 201 9 injury injury NN cord-006870-f5w6fw6q 201 10 have have VBP cord-006870-f5w6fw6q 201 11 poor poor JJ cord-006870-f5w6fw6q 201 12 neurological neurological JJ cord-006870-f5w6fw6q 201 13 recovery recovery NN cord-006870-f5w6fw6q 201 14 . . . cord-006870-f5w6fw6q 202 1 This this DT cord-006870-f5w6fw6q 202 2 created create VBD cord-006870-f5w6fw6q 202 3 a a DT cord-006870-f5w6fw6q 202 4 significant significant JJ cord-006870-f5w6fw6q 202 5 anxiety anxiety NN cord-006870-f5w6fw6q 202 6 in in IN cord-006870-f5w6fw6q 202 7 families family NNS cord-006870-f5w6fw6q 202 8 who who WP cord-006870-f5w6fw6q 202 9 often often RB cord-006870-f5w6fw6q 202 10 request request VBP cord-006870-f5w6fw6q 202 11 early early JJ cord-006870-f5w6fw6q 202 12 prognostication prognostication NN cord-006870-f5w6fw6q 202 13 . . . cord-006870-f5w6fw6q 203 1 This this DT cord-006870-f5w6fw6q 203 2 study study NN cord-006870-f5w6fw6q 203 3 was be VBD cord-006870-f5w6fw6q 203 4 conducted conduct VBN cord-006870-f5w6fw6q 203 5 to to TO cord-006870-f5w6fw6q 203 6 evaluate evaluate VB cord-006870-f5w6fw6q 203 7 possible possible JJ cord-006870-f5w6fw6q 203 8 ultra ultra JJ cord-006870-f5w6fw6q 203 9 - - JJ cord-006870-f5w6fw6q 203 10 early early JJ cord-006870-f5w6fw6q 203 11 prediction prediction NN cord-006870-f5w6fw6q 203 12 of of IN cord-006870-f5w6fw6q 203 13 good good JJ cord-006870-f5w6fw6q 203 14 neurological neurological JJ cord-006870-f5w6fw6q 203 15 recovery recovery NN cord-006870-f5w6fw6q 203 16 in in IN cord-006870-f5w6fw6q 203 17 patients patient NNS cord-006870-f5w6fw6q 203 18 undergoing undergo VBG cord-006870-f5w6fw6q 203 19 hypothermic hypothermic JJ cord-006870-f5w6fw6q 203 20 protocol protocol NN cord-006870-f5w6fw6q 203 21 for for IN cord-006870-f5w6fw6q 203 22 anoxic anoxic JJ cord-006870-f5w6fw6q 203 23 brain brain NN cord-006870-f5w6fw6q 203 24 injury injury NN cord-006870-f5w6fw6q 203 25 Retrospective Retrospective NNP cord-006870-f5w6fw6q 203 26 chart chart NN cord-006870-f5w6fw6q 203 27 review review NN cord-006870-f5w6fw6q 203 28 of of IN cord-006870-f5w6fw6q 203 29 the the DT cord-006870-f5w6fw6q 203 30 patients patient NNS cord-006870-f5w6fw6q 203 31 with with IN cord-006870-f5w6fw6q 203 32 anoxic anoxic JJ cord-006870-f5w6fw6q 203 33 brain brain NN cord-006870-f5w6fw6q 203 34 injury injury NN cord-006870-f5w6fw6q 203 35 was be VBD cord-006870-f5w6fw6q 203 36 conducted conduct VBN cord-006870-f5w6fw6q 203 37 . . . cord-006870-f5w6fw6q 204 1 All all DT cord-006870-f5w6fw6q 204 2 patient patient JJ cord-006870-f5w6fw6q 204 3 underwent undergo VBD cord-006870-f5w6fw6q 204 4 standard standard JJ cord-006870-f5w6fw6q 204 5 evaluation evaluation NN cord-006870-f5w6fw6q 204 6 and and CC cord-006870-f5w6fw6q 204 7 management management NN cord-006870-f5w6fw6q 204 8 in in IN cord-006870-f5w6fw6q 204 9 the the DT cord-006870-f5w6fw6q 204 10 early early JJ cord-006870-f5w6fw6q 204 11 stages stage NNS cord-006870-f5w6fw6q 204 12 of of IN cord-006870-f5w6fw6q 204 13 ICU ICU NNP cord-006870-f5w6fw6q 204 14 care care NN cord-006870-f5w6fw6q 204 15 , , , cord-006870-f5w6fw6q 204 16 including include VBG cord-006870-f5w6fw6q 204 17 initiating initiate VBG cord-006870-f5w6fw6q 204 18 of of IN cord-006870-f5w6fw6q 204 19 hypothermic hypothermic JJ cord-006870-f5w6fw6q 204 20 protocol protocol NN cord-006870-f5w6fw6q 204 21 with with IN cord-006870-f5w6fw6q 204 22 intravenous intravenous JJ cord-006870-f5w6fw6q 204 23 cooling cooling NN cord-006870-f5w6fw6q 204 24 device device NN cord-006870-f5w6fw6q 204 25 . . . cord-006870-f5w6fw6q 205 1 All all DT cord-006870-f5w6fw6q 205 2 patients patient NNS cord-006870-f5w6fw6q 205 3 underwent undergo VBD cord-006870-f5w6fw6q 205 4 evaluations evaluation NNS cord-006870-f5w6fw6q 205 5 with with IN cord-006870-f5w6fw6q 205 6 EEG EEG NNP cord-006870-f5w6fw6q 205 7 and and CC cord-006870-f5w6fw6q 205 8 SSEP SSEP NNPS cord-006870-f5w6fw6q 205 9 within within IN cord-006870-f5w6fw6q 205 10 first first JJ cord-006870-f5w6fw6q 205 11 day day NN cord-006870-f5w6fw6q 205 12 after after IN cord-006870-f5w6fw6q 205 13 admission admission NN cord-006870-f5w6fw6q 205 14 during during IN cord-006870-f5w6fw6q 205 15 hypothermia hypothermia NN cord-006870-f5w6fw6q 205 16 phase phase NN cord-006870-f5w6fw6q 205 17 and and CC cord-006870-f5w6fw6q 205 18 MRI MRI NNP cord-006870-f5w6fw6q 205 19 brain brain NN cord-006870-f5w6fw6q 205 20 after after IN cord-006870-f5w6fw6q 205 21 re re NN cord-006870-f5w6fw6q 205 22 - - NN cord-006870-f5w6fw6q 205 23 warming warming NN cord-006870-f5w6fw6q 205 24 . . . cord-006870-f5w6fw6q 206 1 Total total NN cord-006870-f5w6fw6q 206 2 of of IN cord-006870-f5w6fw6q 206 3 65 65 CD cord-006870-f5w6fw6q 206 4 charts chart NNS cord-006870-f5w6fw6q 206 5 were be VBD cord-006870-f5w6fw6q 206 6 reviewed review VBN cord-006870-f5w6fw6q 206 7 . . . cord-006870-f5w6fw6q 207 1 9 9 CD cord-006870-f5w6fw6q 207 2 patient patient NN cord-006870-f5w6fw6q 207 3 had have VBD cord-006870-f5w6fw6q 207 4 normal normal JJ cord-006870-f5w6fw6q 207 5 SSEP SSEP NNS cord-006870-f5w6fw6q 207 6 and and CC cord-006870-f5w6fw6q 207 7 normal normal JJ cord-006870-f5w6fw6q 207 8 MRI MRI NNP cord-006870-f5w6fw6q 207 9 . . . cord-006870-f5w6fw6q 208 1 All all DT cord-006870-f5w6fw6q 208 2 patients patient NNS cord-006870-f5w6fw6q 208 3 had have VBD cord-006870-f5w6fw6q 208 4 good good JJ cord-006870-f5w6fw6q 208 5 neurological neurological JJ cord-006870-f5w6fw6q 208 6 recovery recovery NN cord-006870-f5w6fw6q 208 7 , , , cord-006870-f5w6fw6q 208 8 except except IN cord-006870-f5w6fw6q 208 9 for for IN cord-006870-f5w6fw6q 208 10 one one CD cord-006870-f5w6fw6q 208 11 patient patient NN cord-006870-f5w6fw6q 208 12 who who WP cord-006870-f5w6fw6q 208 13 died die VBD cord-006870-f5w6fw6q 208 14 secondary secondary JJ cord-006870-f5w6fw6q 208 15 to to IN cord-006870-f5w6fw6q 208 16 severe severe JJ cord-006870-f5w6fw6q 208 17 cardiac cardiac JJ cord-006870-f5w6fw6q 208 18 failure failure NN cord-006870-f5w6fw6q 208 19 EEG EEG NNP cord-006870-f5w6fw6q 208 20 did do VBD cord-006870-f5w6fw6q 208 21 not not RB cord-006870-f5w6fw6q 208 22 have have VB cord-006870-f5w6fw6q 208 23 any any DT cord-006870-f5w6fw6q 208 24 predictive predictive JJ cord-006870-f5w6fw6q 208 25 value value NN cord-006870-f5w6fw6q 208 26 for for IN cord-006870-f5w6fw6q 208 27 the the DT cord-006870-f5w6fw6q 208 28 good good JJ cord-006870-f5w6fw6q 208 29 neurological neurological JJ cord-006870-f5w6fw6q 208 30 outcome outcome NN cord-006870-f5w6fw6q 208 31 when when WRB cord-006870-f5w6fw6q 208 32 it -PRON- PRP cord-006870-f5w6fw6q 208 33 was be VBD cord-006870-f5w6fw6q 208 34 done do VBN cord-006870-f5w6fw6q 208 35 during during IN cord-006870-f5w6fw6q 208 36 hypothermic hypothermic JJ cord-006870-f5w6fw6q 208 37 protocol protocol NN cord-006870-f5w6fw6q 208 38 . . . cord-006870-f5w6fw6q 209 1 Normal normal JJ cord-006870-f5w6fw6q 209 2 SSEP SSEP NNS cord-006870-f5w6fw6q 209 3 may may MD cord-006870-f5w6fw6q 209 4 a a DT cord-006870-f5w6fw6q 209 5 reliable reliable JJ cord-006870-f5w6fw6q 209 6 predictor predictor NN cord-006870-f5w6fw6q 209 7 for for IN cord-006870-f5w6fw6q 209 8 good good JJ cord-006870-f5w6fw6q 209 9 neurological neurological JJ cord-006870-f5w6fw6q 209 10 recovery recovery NN cord-006870-f5w6fw6q 209 11 . . . cord-006870-f5w6fw6q 210 1 Apnea apnea NN cord-006870-f5w6fw6q 210 2 test test NN cord-006870-f5w6fw6q 210 3 is be VBZ cord-006870-f5w6fw6q 210 4 the the DT cord-006870-f5w6fw6q 210 5 essential essential JJ cord-006870-f5w6fw6q 210 6 component component NN cord-006870-f5w6fw6q 210 7 to to TO cord-006870-f5w6fw6q 210 8 confirm confirm VB cord-006870-f5w6fw6q 210 9 brain brain NN cord-006870-f5w6fw6q 210 10 death death NN cord-006870-f5w6fw6q 210 11 by by IN cord-006870-f5w6fw6q 210 12 stimulation stimulation NN cord-006870-f5w6fw6q 210 13 of of IN cord-006870-f5w6fw6q 210 14 respiratory respiratory JJ cord-006870-f5w6fw6q 210 15 center center NN cord-006870-f5w6fw6q 210 16 in in IN cord-006870-f5w6fw6q 210 17 brainstem brainstem NNP cord-006870-f5w6fw6q 210 18 . . . cord-006870-f5w6fw6q 211 1 Guidelines guideline NNS cord-006870-f5w6fw6q 211 2 recommend recommend VBP cord-006870-f5w6fw6q 211 3 that that DT cord-006870-f5w6fw6q 211 4 apnea apnea NN cord-006870-f5w6fw6q 211 5 testing testing NN cord-006870-f5w6fw6q 211 6 should should MD cord-006870-f5w6fw6q 211 7 meet meet VB cord-006870-f5w6fw6q 211 8 the the DT cord-006870-f5w6fw6q 211 9 criteria criterion NNS cord-006870-f5w6fw6q 211 10 of of IN cord-006870-f5w6fw6q 211 11 disconnection disconnection NN cord-006870-f5w6fw6q 211 12 from from IN cord-006870-f5w6fw6q 211 13 mechanical mechanical JJ cord-006870-f5w6fw6q 211 14 ventilator ventilator NN cord-006870-f5w6fw6q 211 15 , , , cord-006870-f5w6fw6q 211 16 and and CC cord-006870-f5w6fw6q 211 17 oxygen oxygen NN cord-006870-f5w6fw6q 211 18 supplying supplying NN cord-006870-f5w6fw6q 211 19 by by IN cord-006870-f5w6fw6q 211 20 catheter catheter NN cord-006870-f5w6fw6q 211 21 . . . cord-006870-f5w6fw6q 212 1 However however RB cord-006870-f5w6fw6q 212 2 , , , cord-006870-f5w6fw6q 212 3 during during IN cord-006870-f5w6fw6q 212 4 the the DT cord-006870-f5w6fw6q 212 5 apnea apnea NN cord-006870-f5w6fw6q 212 6 test test NN cord-006870-f5w6fw6q 212 7 under under IN cord-006870-f5w6fw6q 212 8 this this DT cord-006870-f5w6fw6q 212 9 technique technique NN cord-006870-f5w6fw6q 212 10 , , , cord-006870-f5w6fw6q 212 11 disconnection disconnection NN cord-006870-f5w6fw6q 212 12 from from IN cord-006870-f5w6fw6q 212 13 ventilator ventilator NN cord-006870-f5w6fw6q 212 14 may may MD cord-006870-f5w6fw6q 212 15 induce induce VB cord-006870-f5w6fw6q 212 16 hypoxia hypoxia NN cord-006870-f5w6fw6q 212 17 due due IN cord-006870-f5w6fw6q 212 18 to to IN cord-006870-f5w6fw6q 212 19 abrupt abrupt JJ cord-006870-f5w6fw6q 212 20 decruitment decruitment NN cord-006870-f5w6fw6q 212 21 of of IN cord-006870-f5w6fw6q 212 22 alveoli alveolus NNS cord-006870-f5w6fw6q 212 23 and and CC cord-006870-f5w6fw6q 212 24 pulmonary pulmonary JJ cord-006870-f5w6fw6q 212 25 barotrauma barotrauma NN cord-006870-f5w6fw6q 212 26 such such JJ cord-006870-f5w6fw6q 212 27 as as IN cord-006870-f5w6fw6q 212 28 pneumothorax pneumothorax NN cord-006870-f5w6fw6q 212 29 . . . cord-006870-f5w6fw6q 213 1 There there EX cord-006870-f5w6fw6q 213 2 are be VBP cord-006870-f5w6fw6q 213 3 some some DT cord-006870-f5w6fw6q 213 4 studies study NNS cord-006870-f5w6fw6q 213 5 that that WDT cord-006870-f5w6fw6q 213 6 suggest suggest VBP cord-006870-f5w6fw6q 213 7 continuous continuous JJ cord-006870-f5w6fw6q 213 8 positive positive JJ cord-006870-f5w6fw6q 213 9 airway airway NN cord-006870-f5w6fw6q 213 10 pressure pressure NN cord-006870-f5w6fw6q 213 11 can can MD cord-006870-f5w6fw6q 213 12 be be VB cord-006870-f5w6fw6q 213 13 effective effective JJ cord-006870-f5w6fw6q 213 14 for for IN cord-006870-f5w6fw6q 213 15 patients patient NNS cord-006870-f5w6fw6q 213 16 with with IN cord-006870-f5w6fw6q 213 17 hemodynamically hemodynamically RB cord-006870-f5w6fw6q 213 18 instability instability NN cord-006870-f5w6fw6q 213 19 and and CC cord-006870-f5w6fw6q 213 20 respiratory respiratory JJ cord-006870-f5w6fw6q 213 21 impairment impairment NN cord-006870-f5w6fw6q 213 22 . . . cord-006870-f5w6fw6q 214 1 We -PRON- PRP cord-006870-f5w6fw6q 214 2 suggest suggest VBP cord-006870-f5w6fw6q 214 3 a a DT cord-006870-f5w6fw6q 214 4 novel novel JJ cord-006870-f5w6fw6q 214 5 method method NN cord-006870-f5w6fw6q 214 6 of of IN cord-006870-f5w6fw6q 214 7 apnea apnea NN cord-006870-f5w6fw6q 214 8 test test NN cord-006870-f5w6fw6q 214 9 by by IN cord-006870-f5w6fw6q 214 10 using use VBG cord-006870-f5w6fw6q 214 11 ambu ambu NNP cord-006870-f5w6fw6q 214 12 bag bag NN cord-006870-f5w6fw6q 214 13 with with IN cord-006870-f5w6fw6q 214 14 positive positive JJ cord-006870-f5w6fw6q 214 15 end end NN cord-006870-f5w6fw6q 214 16 - - HYPH cord-006870-f5w6fw6q 214 17 expiratory expiratory NN cord-006870-f5w6fw6q 214 18 pressure pressure NN cord-006870-f5w6fw6q 214 19 ( ( -LRB- cord-006870-f5w6fw6q 214 20 PEEP peep NN cord-006870-f5w6fw6q 214 21 ) ) -RRB- cord-006870-f5w6fw6q 214 22 valve valve NN cord-006870-f5w6fw6q 214 23 to to TO cord-006870-f5w6fw6q 214 24 avoid avoid VB cord-006870-f5w6fw6q 214 25 abrupt abrupt JJ cord-006870-f5w6fw6q 214 26 change change NN cord-006870-f5w6fw6q 214 27 of of IN cord-006870-f5w6fw6q 214 28 PEEP peep NN cord-006870-f5w6fw6q 214 29 during during IN cord-006870-f5w6fw6q 214 30 the the DT cord-006870-f5w6fw6q 214 31 apnea apnea NN cord-006870-f5w6fw6q 214 32 test test NN cord-006870-f5w6fw6q 214 33 . . . cord-006870-f5w6fw6q 215 1 Apnea apnea NN cord-006870-f5w6fw6q 215 2 testing testing NN cord-006870-f5w6fw6q 215 3 was be VBD cord-006870-f5w6fw6q 215 4 performed perform VBN cord-006870-f5w6fw6q 215 5 by by IN cord-006870-f5w6fw6q 215 6 using use VBG cord-006870-f5w6fw6q 215 7 ambu ambu NNP cord-006870-f5w6fw6q 215 8 bag bag NN cord-006870-f5w6fw6q 215 9 with with IN cord-006870-f5w6fw6q 215 10 PEEP peep NN cord-006870-f5w6fw6q 215 11 valve valve NN cord-006870-f5w6fw6q 215 12 to to IN cord-006870-f5w6fw6q 215 13 26 26 CD cord-006870-f5w6fw6q 215 14 adult adult NN cord-006870-f5w6fw6q 215 15 brain brain NN cord-006870-f5w6fw6q 215 16 death death NN cord-006870-f5w6fw6q 215 17 patients patient NNS cord-006870-f5w6fw6q 215 18 . . . cord-006870-f5w6fw6q 216 1 Ambu Ambu NNP cord-006870-f5w6fw6q 216 2 bag bag NN cord-006870-f5w6fw6q 216 3 was be VBD cord-006870-f5w6fw6q 216 4 not not RB cord-006870-f5w6fw6q 216 5 bagging bag VBG cord-006870-f5w6fw6q 216 6 during during IN cord-006870-f5w6fw6q 216 7 the the DT cord-006870-f5w6fw6q 216 8 testing testing NN cord-006870-f5w6fw6q 216 9 and and CC cord-006870-f5w6fw6q 216 10 just just RB cord-006870-f5w6fw6q 216 11 connected connect VBN cord-006870-f5w6fw6q 216 12 to to TO cord-006870-f5w6fw6q 216 13 endotracheal endotracheal VB cord-006870-f5w6fw6q 216 14 tube tube NN cord-006870-f5w6fw6q 216 15 with with IN cord-006870-f5w6fw6q 216 16 10 10 CD cord-006870-f5w6fw6q 216 17 L l NN cord-006870-f5w6fw6q 216 18 / / SYM cord-006870-f5w6fw6q 216 19 min min NN cord-006870-f5w6fw6q 216 20 of of IN cord-006870-f5w6fw6q 216 21 100 100 CD cord-006870-f5w6fw6q 216 22 % % NN cord-006870-f5w6fw6q 216 23 oxygen oxygen NN cord-006870-f5w6fw6q 216 24 . . . cord-006870-f5w6fw6q 217 1 PEEP peep NN cord-006870-f5w6fw6q 217 2 valve valve NN cord-006870-f5w6fw6q 217 3 was be VBD cord-006870-f5w6fw6q 217 4 applied apply VBN cord-006870-f5w6fw6q 217 5 the the DT cord-006870-f5w6fw6q 217 6 same same JJ cord-006870-f5w6fw6q 217 7 PEEP peep NN cord-006870-f5w6fw6q 217 8 of of IN cord-006870-f5w6fw6q 217 9 previous previous JJ cord-006870-f5w6fw6q 217 10 mechanical mechanical JJ cord-006870-f5w6fw6q 217 11 ventilator ventilator NN cord-006870-f5w6fw6q 217 12 . . . cord-006870-f5w6fw6q 218 1 On on IN cord-006870-f5w6fw6q 218 2 the the DT cord-006870-f5w6fw6q 218 3 apnea apnea NN cord-006870-f5w6fw6q 218 4 testing testing NN cord-006870-f5w6fw6q 218 5 , , , cord-006870-f5w6fw6q 218 6 vital vital JJ cord-006870-f5w6fw6q 218 7 signs sign NNS cord-006870-f5w6fw6q 218 8 and and CC cord-006870-f5w6fw6q 218 9 EKG EKG NNP cord-006870-f5w6fw6q 218 10 were be VBD cord-006870-f5w6fw6q 218 11 monitored monitor VBN cord-006870-f5w6fw6q 218 12 . . . cord-006870-f5w6fw6q 219 1 Arterial arterial JJ cord-006870-f5w6fw6q 219 2 blood blood NN cord-006870-f5w6fw6q 219 3 gas gas NN cord-006870-f5w6fw6q 219 4 analysis analysis NN cord-006870-f5w6fw6q 219 5 were be VBD cord-006870-f5w6fw6q 219 6 measured measure VBN cord-006870-f5w6fw6q 219 7 2 2 CD cord-006870-f5w6fw6q 219 8 and and CC cord-006870-f5w6fw6q 219 9 4 4 CD cord-006870-f5w6fw6q 219 10 minutes minute NNS cord-006870-f5w6fw6q 219 11 after after IN cord-006870-f5w6fw6q 219 12 disconnection disconnection NN cord-006870-f5w6fw6q 219 13 from from IN cord-006870-f5w6fw6q 219 14 mechanical mechanical JJ cord-006870-f5w6fw6q 219 15 ventilator ventilator NN cord-006870-f5w6fw6q 219 16 . . . cord-006870-f5w6fw6q 220 1 There there EX cord-006870-f5w6fw6q 220 2 were be VBD cord-006870-f5w6fw6q 220 3 no no DT cord-006870-f5w6fw6q 220 4 significant significant JJ cord-006870-f5w6fw6q 220 5 differences difference NNS cord-006870-f5w6fw6q 220 6 in in IN cord-006870-f5w6fw6q 220 7 mean mean JJ cord-006870-f5w6fw6q 220 8 PaO2 PaO2 NNS cord-006870-f5w6fw6q 220 9 between between IN cord-006870-f5w6fw6q 220 10 before before RB cord-006870-f5w6fw6q 220 11 and and CC cord-006870-f5w6fw6q 220 12 after after IN cord-006870-f5w6fw6q 220 13 apnea apnea NN cord-006870-f5w6fw6q 220 14 test test NN cord-006870-f5w6fw6q 220 15 ( ( -LRB- cord-006870-f5w6fw6q 220 16 275 275 CD cord-006870-f5w6fw6q 220 17 ± ± CD cord-006870-f5w6fw6q 220 18 181 181 CD cord-006870-f5w6fw6q 220 19 and and CC cord-006870-f5w6fw6q 220 20 260 260 CD cord-006870-f5w6fw6q 220 21 ± ± NNP cord-006870-f5w6fw6q 220 22 178 178 CD cord-006870-f5w6fw6q 220 23 , , , cord-006870-f5w6fw6q 220 24 P=0.7 P=0.7 NNP cord-006870-f5w6fw6q 220 25 ) ) -RRB- cord-006870-f5w6fw6q 220 26 . . . cord-006870-f5w6fw6q 221 1 Mean mean JJ cord-006870-f5w6fw6q 221 2 arterial arterial JJ cord-006870-f5w6fw6q 221 3 blood blood NN cord-006870-f5w6fw6q 221 4 pressure pressure NN cord-006870-f5w6fw6q 221 5 were be VBD cord-006870-f5w6fw6q 221 6 90 90 CD cord-006870-f5w6fw6q 221 7 ± ± NNP cord-006870-f5w6fw6q 221 8 17 17 CD cord-006870-f5w6fw6q 221 9 mmHg mmHg NNS cord-006870-f5w6fw6q 221 10 and and CC cord-006870-f5w6fw6q 221 11 90 90 CD cord-006870-f5w6fw6q 221 12 ± ± NNP cord-006870-f5w6fw6q 221 13 22 22 CD cord-006870-f5w6fw6q 221 14 mmHg mmHg NNS cord-006870-f5w6fw6q 221 15 before before RB cord-006870-f5w6fw6q 221 16 and and CC cord-006870-f5w6fw6q 221 17 after after IN cord-006870-f5w6fw6q 221 18 the the DT cord-006870-f5w6fw6q 221 19 test test NN cord-006870-f5w6fw6q 221 20 , , , cord-006870-f5w6fw6q 221 21 respectively respectively RB cord-006870-f5w6fw6q 221 22 . . . cord-006870-f5w6fw6q 222 1 During during IN cord-006870-f5w6fw6q 222 2 the the DT cord-006870-f5w6fw6q 222 3 intervention intervention NN cord-006870-f5w6fw6q 222 4 and and CC cord-006870-f5w6fw6q 222 5 following follow VBG cord-006870-f5w6fw6q 222 6 observation observation NN cord-006870-f5w6fw6q 222 7 , , , cord-006870-f5w6fw6q 222 8 arrhythmia arrhythmia NN cord-006870-f5w6fw6q 222 9 or or CC cord-006870-f5w6fw6q 222 10 pulmonary pulmonary JJ cord-006870-f5w6fw6q 222 11 complications complication NNS cord-006870-f5w6fw6q 222 12 had have VBD cord-006870-f5w6fw6q 222 13 not not RB cord-006870-f5w6fw6q 222 14 occurred occur VBN cord-006870-f5w6fw6q 222 15 . . . cord-006870-f5w6fw6q 223 1 We -PRON- PRP cord-006870-f5w6fw6q 223 2 suggest suggest VBP cord-006870-f5w6fw6q 223 3 a a DT cord-006870-f5w6fw6q 223 4 novel novel JJ cord-006870-f5w6fw6q 223 5 method method NN cord-006870-f5w6fw6q 223 6 of of IN cord-006870-f5w6fw6q 223 7 apnea apnea NN cord-006870-f5w6fw6q 223 8 testing testing NN cord-006870-f5w6fw6q 223 9 which which WDT cord-006870-f5w6fw6q 223 10 is be VBZ cord-006870-f5w6fw6q 223 11 a a DT cord-006870-f5w6fw6q 223 12 simple simple JJ cord-006870-f5w6fw6q 223 13 and and CC cord-006870-f5w6fw6q 223 14 easy easy JJ cord-006870-f5w6fw6q 223 15 technique technique NN cord-006870-f5w6fw6q 223 16 by by IN cord-006870-f5w6fw6q 223 17 using use VBG cord-006870-f5w6fw6q 223 18 ambu ambu NNP cord-006870-f5w6fw6q 223 19 bag bag NN cord-006870-f5w6fw6q 223 20 with with IN cord-006870-f5w6fw6q 223 21 PEEP peep NN cord-006870-f5w6fw6q 223 22 valve valve NN cord-006870-f5w6fw6q 223 23 to to TO cord-006870-f5w6fw6q 223 24 minimize minimize VB cord-006870-f5w6fw6q 223 25 decruitment decruitment NN cord-006870-f5w6fw6q 223 26 of of IN cord-006870-f5w6fw6q 223 27 alveoli alveolus NNS cord-006870-f5w6fw6q 223 28 . . . cord-006870-f5w6fw6q 224 1 This this DT cord-006870-f5w6fw6q 224 2 method method NN cord-006870-f5w6fw6q 224 3 shows show VBZ cord-006870-f5w6fw6q 224 4 vital vital JJ cord-006870-f5w6fw6q 224 5 signs sign NNS cord-006870-f5w6fw6q 224 6 and and CC cord-006870-f5w6fw6q 224 7 respiratory respiratory JJ cord-006870-f5w6fw6q 224 8 oxygenation oxygenation NN cord-006870-f5w6fw6q 224 9 of of IN cord-006870-f5w6fw6q 224 10 the the DT cord-006870-f5w6fw6q 224 11 patients patient NNS cord-006870-f5w6fw6q 224 12 remained remain VBD cord-006870-f5w6fw6q 224 13 stable stable JJ cord-006870-f5w6fw6q 224 14 during during IN cord-006870-f5w6fw6q 224 15 the the DT cord-006870-f5w6fw6q 224 16 test test NN cord-006870-f5w6fw6q 224 17 . . . cord-006870-f5w6fw6q 225 1 Declaration Declaration NNP cord-006870-f5w6fw6q 225 2 of of IN cord-006870-f5w6fw6q 225 3 brain brain NN cord-006870-f5w6fw6q 225 4 death death NN cord-006870-f5w6fw6q 225 5 based base VBN cord-006870-f5w6fw6q 225 6 on on IN cord-006870-f5w6fw6q 225 7 clinical clinical JJ cord-006870-f5w6fw6q 225 8 exam exam NN cord-006870-f5w6fw6q 225 9 has have VBZ cord-006870-f5w6fw6q 225 10 been be VBN cord-006870-f5w6fw6q 225 11 plagued plague VBN cord-006870-f5w6fw6q 225 12 with with IN cord-006870-f5w6fw6q 225 13 challenges challenge NNS cord-006870-f5w6fw6q 225 14 . . . cord-006870-f5w6fw6q 226 1 As as IN cord-006870-f5w6fw6q 226 2 a a DT cord-006870-f5w6fw6q 226 3 result result NN cord-006870-f5w6fw6q 226 4 , , , cord-006870-f5w6fw6q 226 5 ancillary ancillary JJ cord-006870-f5w6fw6q 226 6 testing testing NN cord-006870-f5w6fw6q 226 7 such such JJ cord-006870-f5w6fw6q 226 8 as as IN cord-006870-f5w6fw6q 226 9 nuclear nuclear JJ cord-006870-f5w6fw6q 226 10 scintigraphy scintigraphy NN cord-006870-f5w6fw6q 226 11 cerebral cerebral JJ cord-006870-f5w6fw6q 226 12 blood blood NN cord-006870-f5w6fw6q 226 13 flow flow NN cord-006870-f5w6fw6q 226 14 ( ( -LRB- cord-006870-f5w6fw6q 226 15 CBF CBF NNP cord-006870-f5w6fw6q 226 16 ) ) -RRB- cord-006870-f5w6fw6q 226 17 studies study NNS cord-006870-f5w6fw6q 226 18 have have VBP cord-006870-f5w6fw6q 226 19 been be VBN cord-006870-f5w6fw6q 226 20 recommended recommend VBN cord-006870-f5w6fw6q 226 21 . . . cord-006870-f5w6fw6q 227 1 We -PRON- PRP cord-006870-f5w6fw6q 227 2 present present VBP cord-006870-f5w6fw6q 227 3 a a DT cord-006870-f5w6fw6q 227 4 case case NN cord-006870-f5w6fw6q 227 5 in in IN cord-006870-f5w6fw6q 227 6 which which WDT cord-006870-f5w6fw6q 227 7 the the DT cord-006870-f5w6fw6q 227 8 apnea apnea NN cord-006870-f5w6fw6q 227 9 test test NN cord-006870-f5w6fw6q 227 10 could could MD cord-006870-f5w6fw6q 227 11 not not RB cord-006870-f5w6fw6q 227 12 be be VB cord-006870-f5w6fw6q 227 13 completed complete VBN cord-006870-f5w6fw6q 227 14 due due JJ cord-006870-f5w6fw6q 227 15 to to IN cord-006870-f5w6fw6q 227 16 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 227 17 instability instability NN cord-006870-f5w6fw6q 227 18 and and CC cord-006870-f5w6fw6q 227 19 where where WRB cord-006870-f5w6fw6q 227 20 the the DT cord-006870-f5w6fw6q 227 21 nuclear nuclear JJ cord-006870-f5w6fw6q 227 22 scintigraphy scintigraphy NN cord-006870-f5w6fw6q 227 23 CBF CBF NNP cord-006870-f5w6fw6q 227 24 study study NN cord-006870-f5w6fw6q 227 25 resulted result VBD cord-006870-f5w6fw6q 227 26 in in IN cord-006870-f5w6fw6q 227 27 a a DT cord-006870-f5w6fw6q 227 28 false false JJ cord-006870-f5w6fw6q 227 29 declaration declaration NN cord-006870-f5w6fw6q 227 30 of of IN cord-006870-f5w6fw6q 227 31 brain brain NN cord-006870-f5w6fw6q 227 32 death death NN cord-006870-f5w6fw6q 227 33 . . . cord-006870-f5w6fw6q 228 1 A a DT cord-006870-f5w6fw6q 228 2 59 59 CD cord-006870-f5w6fw6q 228 3 y y NN cord-006870-f5w6fw6q 228 4 / / SYM cord-006870-f5w6fw6q 228 5 o o NN cord-006870-f5w6fw6q 228 6 male male NN cord-006870-f5w6fw6q 228 7 was be VBD cord-006870-f5w6fw6q 228 8 admitted admit VBN cord-006870-f5w6fw6q 228 9 with with IN cord-006870-f5w6fw6q 228 10 bilateral bilateral JJ cord-006870-f5w6fw6q 228 11 hearing hearing NN cord-006870-f5w6fw6q 228 12 loss loss NN cord-006870-f5w6fw6q 228 13 and and CC cord-006870-f5w6fw6q 228 14 confusion confusion NN cord-006870-f5w6fw6q 228 15 . . . cord-006870-f5w6fw6q 229 1 On on IN cord-006870-f5w6fw6q 229 2 day day NN cord-006870-f5w6fw6q 229 3 two two CD cord-006870-f5w6fw6q 229 4 , , , cord-006870-f5w6fw6q 229 5 the the DT cord-006870-f5w6fw6q 229 6 patient patient NN cord-006870-f5w6fw6q 229 7 developed develop VBD cord-006870-f5w6fw6q 229 8 blurred blurred JJ cord-006870-f5w6fw6q 229 9 vision vision NN cord-006870-f5w6fw6q 229 10 , , , cord-006870-f5w6fw6q 229 11 and and CC cord-006870-f5w6fw6q 229 12 an an DT cord-006870-f5w6fw6q 229 13 MRI MRI NNP cord-006870-f5w6fw6q 229 14 confirmed confirm VBD cord-006870-f5w6fw6q 229 15 bilateral bilateral JJ cord-006870-f5w6fw6q 229 16 cerebellar cerebellar JJ cord-006870-f5w6fw6q 229 17 and and CC cord-006870-f5w6fw6q 229 18 pontine pontine JJ cord-006870-f5w6fw6q 229 19 infarctions infarction NNS cord-006870-f5w6fw6q 229 20 . . . cord-006870-f5w6fw6q 230 1 By by IN cord-006870-f5w6fw6q 230 2 day day NN cord-006870-f5w6fw6q 230 3 four four CD cord-006870-f5w6fw6q 230 4 , , , cord-006870-f5w6fw6q 230 5 he -PRON- PRP cord-006870-f5w6fw6q 230 6 had have VBD cord-006870-f5w6fw6q 230 7 developed develop VBN cord-006870-f5w6fw6q 230 8 diffuse diffuse JJ cord-006870-f5w6fw6q 230 9 cerebral cerebral JJ cord-006870-f5w6fw6q 230 10 edema edema NN cord-006870-f5w6fw6q 230 11 in in IN cord-006870-f5w6fw6q 230 12 the the DT cord-006870-f5w6fw6q 230 13 cerebellum cerebellum NN cord-006870-f5w6fw6q 230 14 , , , cord-006870-f5w6fw6q 230 15 brainstem brainstem NN cord-006870-f5w6fw6q 230 16 , , , cord-006870-f5w6fw6q 230 17 and and CC cord-006870-f5w6fw6q 230 18 bilateral bilateral JJ cord-006870-f5w6fw6q 230 19 occipital occipital JJ cord-006870-f5w6fw6q 230 20 lobes lobe NNS cord-006870-f5w6fw6q 230 21 , , , cord-006870-f5w6fw6q 230 22 and and CC cord-006870-f5w6fw6q 230 23 we -PRON- PRP cord-006870-f5w6fw6q 230 24 proceeded proceed VBD cord-006870-f5w6fw6q 230 25 with with IN cord-006870-f5w6fw6q 230 26 the the DT cord-006870-f5w6fw6q 230 27 clinical clinical JJ cord-006870-f5w6fw6q 230 28 exam exam NN cord-006870-f5w6fw6q 230 29 for for IN cord-006870-f5w6fw6q 230 30 brain brain NN cord-006870-f5w6fw6q 230 31 death death NN cord-006870-f5w6fw6q 230 32 . . . cord-006870-f5w6fw6q 231 1 All all DT cord-006870-f5w6fw6q 231 2 cranial cranial JJ cord-006870-f5w6fw6q 231 3 reflexes reflex NNS cord-006870-f5w6fw6q 231 4 were be VBD cord-006870-f5w6fw6q 231 5 absent absent JJ cord-006870-f5w6fw6q 231 6 ; ; : cord-006870-f5w6fw6q 231 7 however however RB cord-006870-f5w6fw6q 231 8 the the DT cord-006870-f5w6fw6q 231 9 apnea apnea NN cord-006870-f5w6fw6q 231 10 exam exam NN cord-006870-f5w6fw6q 231 11 could could MD cord-006870-f5w6fw6q 231 12 not not RB cord-006870-f5w6fw6q 231 13 be be VB cord-006870-f5w6fw6q 231 14 completed complete VBN cord-006870-f5w6fw6q 231 15 due due JJ cord-006870-f5w6fw6q 231 16 to to IN cord-006870-f5w6fw6q 231 17 blood blood NN cord-006870-f5w6fw6q 231 18 pressure pressure NN cord-006870-f5w6fw6q 231 19 instability instability NN cord-006870-f5w6fw6q 231 20 . . . cord-006870-f5w6fw6q 232 1 A a DT cord-006870-f5w6fw6q 232 2 nuclear nuclear JJ cord-006870-f5w6fw6q 232 3 scintigraphy scintigraphy NN cord-006870-f5w6fw6q 232 4 CBF CBF NNP cord-006870-f5w6fw6q 232 5 study study NN cord-006870-f5w6fw6q 232 6 revealed reveal VBD cord-006870-f5w6fw6q 232 7 the the DT cord-006870-f5w6fw6q 232 8 complete complete JJ cord-006870-f5w6fw6q 232 9 absence absence NN cord-006870-f5w6fw6q 232 10 of of IN cord-006870-f5w6fw6q 232 11 radiotracer radiotracer NN cord-006870-f5w6fw6q 232 12 activity activity NN cord-006870-f5w6fw6q 232 13 , , , cord-006870-f5w6fw6q 232 14 and and CC cord-006870-f5w6fw6q 232 15 the the DT cord-006870-f5w6fw6q 232 16 patient patient NN cord-006870-f5w6fw6q 232 17 was be VBD cord-006870-f5w6fw6q 232 18 pronounced pronounce VBN cord-006870-f5w6fw6q 232 19 dead dead JJ cord-006870-f5w6fw6q 232 20 . . . cord-006870-f5w6fw6q 233 1 Two two CD cord-006870-f5w6fw6q 233 2 hours hour NNS cord-006870-f5w6fw6q 233 3 later later RB cord-006870-f5w6fw6q 233 4 , , , cord-006870-f5w6fw6q 233 5 the the DT cord-006870-f5w6fw6q 233 6 patient patient NN cord-006870-f5w6fw6q 233 7 regained regain VBD cord-006870-f5w6fw6q 233 8 a a DT cord-006870-f5w6fw6q 233 9 gag gag NN cord-006870-f5w6fw6q 233 10 reflex reflex NN cord-006870-f5w6fw6q 233 11 . . . cord-006870-f5w6fw6q 234 1 On on IN cord-006870-f5w6fw6q 234 2 the the DT cord-006870-f5w6fw6q 234 3 following follow VBG cord-006870-f5w6fw6q 234 4 day day NN cord-006870-f5w6fw6q 234 5 , , , cord-006870-f5w6fw6q 234 6 the the DT cord-006870-f5w6fw6q 234 7 clinical clinical JJ cord-006870-f5w6fw6q 234 8 exam exam NN cord-006870-f5w6fw6q 234 9 , , , cord-006870-f5w6fw6q 234 10 with with IN cord-006870-f5w6fw6q 234 11 the the DT cord-006870-f5w6fw6q 234 12 exception exception NN cord-006870-f5w6fw6q 234 13 of of IN cord-006870-f5w6fw6q 234 14 apnea apnea NN cord-006870-f5w6fw6q 234 15 testing testing NN cord-006870-f5w6fw6q 234 16 , , , cord-006870-f5w6fw6q 234 17 was be VBD cord-006870-f5w6fw6q 234 18 again again RB cord-006870-f5w6fw6q 234 19 consistent consistent JJ cord-006870-f5w6fw6q 234 20 with with IN cord-006870-f5w6fw6q 234 21 brain brain NN cord-006870-f5w6fw6q 234 22 death death NN cord-006870-f5w6fw6q 234 23 . . . cord-006870-f5w6fw6q 235 1 A a DT cord-006870-f5w6fw6q 235 2 cerebral cerebral JJ cord-006870-f5w6fw6q 235 3 angiogram angiogram NN cord-006870-f5w6fw6q 235 4 was be VBD cord-006870-f5w6fw6q 235 5 performed perform VBN cord-006870-f5w6fw6q 235 6 and and CC cord-006870-f5w6fw6q 235 7 demonstrated demonstrate VBD cord-006870-f5w6fw6q 235 8 normal normal JJ cord-006870-f5w6fw6q 235 9 blood blood NN cord-006870-f5w6fw6q 235 10 flow flow NN cord-006870-f5w6fw6q 235 11 to to IN cord-006870-f5w6fw6q 235 12 the the DT cord-006870-f5w6fw6q 235 13 anterior anterior JJ cord-006870-f5w6fw6q 235 14 circulation circulation NN cord-006870-f5w6fw6q 235 15 . . . cord-006870-f5w6fw6q 236 1 The the DT cord-006870-f5w6fw6q 236 2 patient patient NN cord-006870-f5w6fw6q 236 3 was be VBD cord-006870-f5w6fw6q 236 4 ultimately ultimately RB cord-006870-f5w6fw6q 236 5 pronounced pronounce VBN cord-006870-f5w6fw6q 236 6 dead dead JJ cord-006870-f5w6fw6q 236 7 on on IN cord-006870-f5w6fw6q 236 8 day day NN cord-006870-f5w6fw6q 236 9 eight eight CD cord-006870-f5w6fw6q 236 10 after after IN cord-006870-f5w6fw6q 236 11 two two CD cord-006870-f5w6fw6q 236 12 separate separate JJ cord-006870-f5w6fw6q 236 13 complete complete JJ cord-006870-f5w6fw6q 236 14 clinical clinical JJ cord-006870-f5w6fw6q 236 15 brain brain NN cord-006870-f5w6fw6q 236 16 death death NN cord-006870-f5w6fw6q 236 17 exams exam NNS cord-006870-f5w6fw6q 236 18 , , , cord-006870-f5w6fw6q 236 19 including include VBG cord-006870-f5w6fw6q 236 20 apnea apnea NN cord-006870-f5w6fw6q 236 21 testing testing NN cord-006870-f5w6fw6q 236 22 , , , cord-006870-f5w6fw6q 236 23 were be VBD cord-006870-f5w6fw6q 236 24 performed perform VBN cord-006870-f5w6fw6q 236 25 . . . cord-006870-f5w6fw6q 237 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 237 2 angiography angiography NN cord-006870-f5w6fw6q 237 3 showed show VBD cord-006870-f5w6fw6q 237 4 essentially essentially RB cord-006870-f5w6fw6q 237 5 normal normal JJ cord-006870-f5w6fw6q 237 6 blood blood NN cord-006870-f5w6fw6q 237 7 flow flow NN cord-006870-f5w6fw6q 237 8 where where WRB cord-006870-f5w6fw6q 237 9 nuclear nuclear JJ cord-006870-f5w6fw6q 237 10 scintigraphy scintigraphy NN cord-006870-f5w6fw6q 237 11 showed show VBD cord-006870-f5w6fw6q 237 12 no no DT cord-006870-f5w6fw6q 237 13 blood blood NN cord-006870-f5w6fw6q 237 14 flow flow NN cord-006870-f5w6fw6q 237 15 . . . cord-006870-f5w6fw6q 238 1 Nuclear nuclear JJ cord-006870-f5w6fw6q 238 2 scintigraphy scintigraphy NN cord-006870-f5w6fw6q 239 1 CBF CBF NNP cord-006870-f5w6fw6q 239 2 studies study NNS cord-006870-f5w6fw6q 239 3 are be VBP cord-006870-f5w6fw6q 239 4 commonly commonly RB cord-006870-f5w6fw6q 239 5 recommended recommend VBN cord-006870-f5w6fw6q 239 6 when when WRB cord-006870-f5w6fw6q 239 7 apnea apnea NN cord-006870-f5w6fw6q 239 8 testing testing NN cord-006870-f5w6fw6q 239 9 can can MD cord-006870-f5w6fw6q 239 10 not not RB cord-006870-f5w6fw6q 239 11 be be VB cord-006870-f5w6fw6q 239 12 completed complete VBN cord-006870-f5w6fw6q 239 13 . . . cord-006870-f5w6fw6q 240 1 Given give VBN cord-006870-f5w6fw6q 240 2 the the DT cord-006870-f5w6fw6q 240 3 dramatic dramatic JJ cord-006870-f5w6fw6q 240 4 differences difference NNS cord-006870-f5w6fw6q 240 5 in in IN cord-006870-f5w6fw6q 240 6 the the DT cord-006870-f5w6fw6q 240 7 results result NNS cord-006870-f5w6fw6q 240 8 observed observe VBN cord-006870-f5w6fw6q 240 9 between between IN cord-006870-f5w6fw6q 240 10 these these DT cord-006870-f5w6fw6q 240 11 modalities modality NNS cord-006870-f5w6fw6q 240 12 , , , cord-006870-f5w6fw6q 240 13 a a DT cord-006870-f5w6fw6q 240 14 reevaluation reevaluation NN cord-006870-f5w6fw6q 240 15 of of IN cord-006870-f5w6fw6q 240 16 this this DT cord-006870-f5w6fw6q 240 17 practice practice NN cord-006870-f5w6fw6q 240 18 should should MD cord-006870-f5w6fw6q 240 19 be be VB cord-006870-f5w6fw6q 240 20 considered consider VBN cord-006870-f5w6fw6q 240 21 . . . cord-006870-f5w6fw6q 241 1 Patients patient NNS cord-006870-f5w6fw6q 241 2 ' ' POS cord-006870-f5w6fw6q 241 3 perceptions perception NNS cord-006870-f5w6fw6q 241 4 of of IN cord-006870-f5w6fw6q 241 5 recovery recovery NN cord-006870-f5w6fw6q 241 6 moderate moderate JJ cord-006870-f5w6fw6q 241 7 outcomes outcome NNS cord-006870-f5w6fw6q 241 8 , , , cord-006870-f5w6fw6q 241 9 however however RB cord-006870-f5w6fw6q 241 10 studies study NNS cord-006870-f5w6fw6q 241 11 exploring explore VBG cord-006870-f5w6fw6q 241 12 the the DT cord-006870-f5w6fw6q 241 13 specific specific JJ cord-006870-f5w6fw6q 241 14 cognitive cognitive JJ cord-006870-f5w6fw6q 241 15 , , , cord-006870-f5w6fw6q 241 16 functional functional JJ cord-006870-f5w6fw6q 241 17 , , , cord-006870-f5w6fw6q 241 18 and and CC cord-006870-f5w6fw6q 241 19 psychological psychological JJ cord-006870-f5w6fw6q 241 20 domains domain NNS cord-006870-f5w6fw6q 241 21 associated associate VBN cord-006870-f5w6fw6q 241 22 with with IN cord-006870-f5w6fw6q 241 23 subjective subjective JJ cord-006870-f5w6fw6q 241 24 perceptions perception NNS cord-006870-f5w6fw6q 241 25 of of IN cord-006870-f5w6fw6q 241 26 recovery recovery NN cord-006870-f5w6fw6q 241 27 at at IN cord-006870-f5w6fw6q 241 28 hospital hospital NN cord-006870-f5w6fw6q 241 29 discharge discharge NN cord-006870-f5w6fw6q 241 30 after after IN cord-006870-f5w6fw6q 241 31 cardiac cardiac JJ cord-006870-f5w6fw6q 241 32 arrest arrest NN cord-006870-f5w6fw6q 241 33 ( ( -LRB- cord-006870-f5w6fw6q 241 34 CA CA NNP cord-006870-f5w6fw6q 241 35 ) ) -RRB- cord-006870-f5w6fw6q 241 36 are be VBP cord-006870-f5w6fw6q 241 37 lacking lack VBG cord-006870-f5w6fw6q 241 38 . . . cord-006870-f5w6fw6q 242 1 This this DT cord-006870-f5w6fw6q 242 2 is be VBZ cord-006870-f5w6fw6q 242 3 a a DT cord-006870-f5w6fw6q 242 4 prospective prospective JJ cord-006870-f5w6fw6q 242 5 , , , cord-006870-f5w6fw6q 242 6 observational observational JJ cord-006870-f5w6fw6q 242 7 cohort cohort NN cord-006870-f5w6fw6q 242 8 of of IN cord-006870-f5w6fw6q 242 9 patients patient NNS cord-006870-f5w6fw6q 242 10 admitted admit VBN cord-006870-f5w6fw6q 242 11 to to IN cord-006870-f5w6fw6q 242 12 Columbia Columbia NNP cord-006870-f5w6fw6q 242 13 University University NNP cord-006870-f5w6fw6q 242 14 Medical Medical NNP cord-006870-f5w6fw6q 242 15 Center Center NNP cord-006870-f5w6fw6q 242 16 after after IN cord-006870-f5w6fw6q 242 17 CA CA NNP cord-006870-f5w6fw6q 242 18 , , , cord-006870-f5w6fw6q 242 19 and and CC cord-006870-f5w6fw6q 242 20 survived survive VBD cord-006870-f5w6fw6q 242 21 to to IN cord-006870-f5w6fw6q 242 22 hospital hospital NN cord-006870-f5w6fw6q 242 23 discharge discharge NN cord-006870-f5w6fw6q 242 24 between between IN cord-006870-f5w6fw6q 242 25 9/2015 9/2015 CD cord-006870-f5w6fw6q 242 26 - - HYPH cord-006870-f5w6fw6q 242 27 5/2017 5/2017 CD cord-006870-f5w6fw6q 242 28 . . . cord-006870-f5w6fw6q 243 1 Patients patient NNS cord-006870-f5w6fw6q 243 2 with with IN cord-006870-f5w6fw6q 243 3 sufficient sufficient JJ cord-006870-f5w6fw6q 243 4 mental mental JJ cord-006870-f5w6fw6q 243 5 status status NN cord-006870-f5w6fw6q 243 6 to to TO cord-006870-f5w6fw6q 243 7 perform perform VB cord-006870-f5w6fw6q 243 8 a a DT cord-006870-f5w6fw6q 243 9 neuropsychological neuropsychological JJ cord-006870-f5w6fw6q 243 10 exam exam NN cord-006870-f5w6fw6q 243 11 and and CC cord-006870-f5w6fw6q 243 12 a a DT cord-006870-f5w6fw6q 243 13 questionnaire questionnaire NN cord-006870-f5w6fw6q 243 14 at at IN cord-006870-f5w6fw6q 243 15 discharge discharge NN cord-006870-f5w6fw6q 243 16 were be VBD cord-006870-f5w6fw6q 243 17 included include VBN cord-006870-f5w6fw6q 243 18 . . . cord-006870-f5w6fw6q 244 1 Subjective subjective JJ cord-006870-f5w6fw6q 244 2 perceptions perception NNS cord-006870-f5w6fw6q 244 3 of of IN cord-006870-f5w6fw6q 244 4 recovery recovery NN cord-006870-f5w6fw6q 244 5 were be VBD cord-006870-f5w6fw6q 244 6 assessed assess VBN cord-006870-f5w6fw6q 244 7 via via IN cord-006870-f5w6fw6q 244 8 responses response NNS cord-006870-f5w6fw6q 244 9 to to IN cord-006870-f5w6fw6q 244 10 the the DT cord-006870-f5w6fw6q 244 11 forced force VBN cord-006870-f5w6fw6q 244 12 - - HYPH cord-006870-f5w6fw6q 244 13 choice choice NN cord-006870-f5w6fw6q 244 14 dichotomized dichotomize VBN cord-006870-f5w6fw6q 244 15 question question NN cord-006870-f5w6fw6q 244 16 , , , cord-006870-f5w6fw6q 244 17 " " '' cord-006870-f5w6fw6q 245 1 Do do VBP cord-006870-f5w6fw6q 245 2 you -PRON- PRP cord-006870-f5w6fw6q 245 3 feel feel VB cord-006870-f5w6fw6q 245 4 that that IN cord-006870-f5w6fw6q 245 5 you -PRON- PRP cord-006870-f5w6fw6q 245 6 have have VBP cord-006870-f5w6fw6q 245 7 made make VBN cord-006870-f5w6fw6q 245 8 a a DT cord-006870-f5w6fw6q 245 9 complete complete JJ cord-006870-f5w6fw6q 245 10 recovery recovery NN cord-006870-f5w6fw6q 245 11 from from IN cord-006870-f5w6fw6q 245 12 the the DT cord-006870-f5w6fw6q 245 13 arrest?"Objective arrest?"objective CD cord-006870-f5w6fw6q 245 14 outcome outcome NN cord-006870-f5w6fw6q 245 15 measures measure NNS cord-006870-f5w6fw6q 245 16 of of IN cord-006870-f5w6fw6q 245 17 recovery recovery NN cord-006870-f5w6fw6q 245 18 included include VBN cord-006870-f5w6fw6q 245 19 : : : cord-006870-f5w6fw6q 245 20 Repeatable repeatable JJ cord-006870-f5w6fw6q 245 21 Battery battery NN cord-006870-f5w6fw6q 245 22 for for IN cord-006870-f5w6fw6q 245 23 Neuropsychological Neuropsychological NNP cord-006870-f5w6fw6q 245 24 Status status NN cord-006870-f5w6fw6q 245 25 ( ( -LRB- cord-006870-f5w6fw6q 245 26 RBANS RBANS NNP cord-006870-f5w6fw6q 245 27 ) ) -RRB- cord-006870-f5w6fw6q 245 28 , , , cord-006870-f5w6fw6q 245 29 Modified Modified NNP cord-006870-f5w6fw6q 245 30 Lawton Lawton NNP cord-006870-f5w6fw6q 245 31 Physical Physical NNP cord-006870-f5w6fw6q 245 32 Self Self NNP cord-006870-f5w6fw6q 245 33 - - HYPH cord-006870-f5w6fw6q 245 34 Maintenance Maintenance NNP cord-006870-f5w6fw6q 245 35 Scale scale NN cord-006870-f5w6fw6q 245 36 ( ( -LRB- cord-006870-f5w6fw6q 245 37 L L NNP cord-006870-f5w6fw6q 245 38 - - HYPH cord-006870-f5w6fw6q 245 39 ADL ADL NNP cord-006870-f5w6fw6q 245 40 ) ) -RRB- cord-006870-f5w6fw6q 245 41 , , , cord-006870-f5w6fw6q 245 42 Barthel Barthel NNP cord-006870-f5w6fw6q 245 43 Index Index NNP cord-006870-f5w6fw6q 245 44 ( ( -LRB- cord-006870-f5w6fw6q 245 45 BI BI NNP cord-006870-f5w6fw6q 245 46 ) ) -RRB- cord-006870-f5w6fw6q 245 47 , , , cord-006870-f5w6fw6q 245 48 Cerebral Cerebral NNP cord-006870-f5w6fw6q 245 49 Performance Performance NNP cord-006870-f5w6fw6q 245 50 Category Category NNP cord-006870-f5w6fw6q 245 51 Scale Scale NNP cord-006870-f5w6fw6q 245 52 ( ( -LRB- cord-006870-f5w6fw6q 245 53 CPC CPC NNP cord-006870-f5w6fw6q 245 54 ) ) -RRB- cord-006870-f5w6fw6q 245 55 , , , cord-006870-f5w6fw6q 245 56 Center Center NNP cord-006870-f5w6fw6q 245 57 for for IN cord-006870-f5w6fw6q 245 58 Epidemiological Epidemiological NNP cord-006870-f5w6fw6q 245 59 Studies Studies NNPS cord-006870-f5w6fw6q 245 60 - - HYPH cord-006870-f5w6fw6q 245 61 Depression depression NN cord-006870-f5w6fw6q 245 62 scale scale NN cord-006870-f5w6fw6q 245 63 ( ( -LRB- cord-006870-f5w6fw6q 245 64 CES CES NNP cord-006870-f5w6fw6q 245 65 - - HYPH cord-006870-f5w6fw6q 245 66 D D NNP cord-006870-f5w6fw6q 245 67 ) ) -RRB- cord-006870-f5w6fw6q 245 68 , , , cord-006870-f5w6fw6q 245 69 and and CC cord-006870-f5w6fw6q 245 70 Post Post NNP cord-006870-f5w6fw6q 245 71 traumatic traumatic JJ cord-006870-f5w6fw6q 245 72 stress stress NN cord-006870-f5w6fw6q 245 73 disorder disorder NN cord-006870-f5w6fw6q 245 74 - - HYPH cord-006870-f5w6fw6q 245 75 checklist checklist NN cord-006870-f5w6fw6q 245 76 ( ( -LRB- cord-006870-f5w6fw6q 245 77 PTSD PTSD NNP cord-006870-f5w6fw6q 245 78 - - HYPH cord-006870-f5w6fw6q 245 79 C C NNP cord-006870-f5w6fw6q 245 80 ) ) -RRB- cord-006870-f5w6fw6q 245 81 . . . cord-006870-f5w6fw6q 246 1 Chi Chi NNP cord-006870-f5w6fw6q 246 2 - - HYPH cord-006870-f5w6fw6q 246 3 square square JJ cord-006870-f5w6fw6q 246 4 , , , cord-006870-f5w6fw6q 246 5 Wilcoxon Wilcoxon NNP cord-006870-f5w6fw6q 246 6 - - HYPH cord-006870-f5w6fw6q 246 7 Rank Rank NNP cord-006870-f5w6fw6q 246 8 Sum Sum NNP cord-006870-f5w6fw6q 246 9 , , , cord-006870-f5w6fw6q 246 10 and and CC cord-006870-f5w6fw6q 246 11 logistic logistic JJ cord-006870-f5w6fw6q 246 12 regression regression NN cord-006870-f5w6fw6q 246 13 were be VBD cord-006870-f5w6fw6q 246 14 used use VBN cord-006870-f5w6fw6q 246 15 to to TO cord-006870-f5w6fw6q 246 16 compare compare VB cord-006870-f5w6fw6q 246 17 the the DT cord-006870-f5w6fw6q 246 18 respondents respondent NNS cord-006870-f5w6fw6q 246 19 , , , cord-006870-f5w6fw6q 246 20 and and CC cord-006870-f5w6fw6q 246 21 determine determine VB cord-006870-f5w6fw6q 246 22 factors factor NNS cord-006870-f5w6fw6q 246 23 associated associate VBN cord-006870-f5w6fw6q 246 24 with with IN cord-006870-f5w6fw6q 246 25 subjective subjective JJ cord-006870-f5w6fw6q 246 26 perceptions perception NNS cord-006870-f5w6fw6q 246 27 of of IN cord-006870-f5w6fw6q 246 28 recovery recovery NN cord-006870-f5w6fw6q 246 29 . . . cord-006870-f5w6fw6q 247 1 64 64 CD cord-006870-f5w6fw6q 247 2 patients patient NNS cord-006870-f5w6fw6q 247 3 were be VBD cord-006870-f5w6fw6q 247 4 included include VBN cord-006870-f5w6fw6q 247 5 with with IN cord-006870-f5w6fw6q 247 6 mean mean JJ cord-006870-f5w6fw6q 247 7 age age NN cord-006870-f5w6fw6q 247 8 of of IN cord-006870-f5w6fw6q 247 9 52±17 52±17 CD cord-006870-f5w6fw6q 247 10 years year NNS cord-006870-f5w6fw6q 247 11 ; ; : cord-006870-f5w6fw6q 247 12 58 58 CD cord-006870-f5w6fw6q 247 13 % % NN cord-006870-f5w6fw6q 247 14 were be VBD cord-006870-f5w6fw6q 247 15 men man NNS cord-006870-f5w6fw6q 247 16 and and CC cord-006870-f5w6fw6q 247 17 48 48 CD cord-006870-f5w6fw6q 247 18 % % NN cord-006870-f5w6fw6q 247 19 were be VBD cord-006870-f5w6fw6q 247 20 white white JJ cord-006870-f5w6fw6q 247 21 . . . cord-006870-f5w6fw6q 248 1 67 67 CD cord-006870-f5w6fw6q 248 2 % % NN cord-006870-f5w6fw6q 248 3 responded respond VBD cord-006870-f5w6fw6q 248 4 not not RB cord-006870-f5w6fw6q 248 5 having have VBG cord-006870-f5w6fw6q 248 6 made make VBN cord-006870-f5w6fw6q 248 7 a a DT cord-006870-f5w6fw6q 248 8 complete complete JJ cord-006870-f5w6fw6q 248 9 recovery recovery NN cord-006870-f5w6fw6q 248 10 . . . cord-006870-f5w6fw6q 249 1 No no DT cord-006870-f5w6fw6q 249 2 significant significant JJ cord-006870-f5w6fw6q 249 3 differences difference NNS cord-006870-f5w6fw6q 249 4 were be VBD cord-006870-f5w6fw6q 249 5 found find VBN cord-006870-f5w6fw6q 249 6 between between IN cord-006870-f5w6fw6q 249 7 respondents respondent NNS cord-006870-f5w6fw6q 249 8 in in IN cord-006870-f5w6fw6q 249 9 terms term NNS cord-006870-f5w6fw6q 249 10 of of IN cord-006870-f5w6fw6q 249 11 demographics demographic NNS cord-006870-f5w6fw6q 249 12 , , , cord-006870-f5w6fw6q 249 13 charlson charlson NNP cord-006870-f5w6fw6q 249 14 comorbidity comorbidity NNP cord-006870-f5w6fw6q 249 15 index index NN cord-006870-f5w6fw6q 249 16 , , , cord-006870-f5w6fw6q 249 17 arrest arrest NN cord-006870-f5w6fw6q 249 18 - - HYPH cord-006870-f5w6fw6q 249 19 related relate VBN cord-006870-f5w6fw6q 249 20 variables variable NNS cord-006870-f5w6fw6q 249 21 , , , cord-006870-f5w6fw6q 249 22 RBANS RBANS NNPS cord-006870-f5w6fw6q 249 23 , , , cord-006870-f5w6fw6q 249 24 L L NNP cord-006870-f5w6fw6q 249 25 - - HYPH cord-006870-f5w6fw6q 249 26 ADL ADL NNP cord-006870-f5w6fw6q 249 27 , , , cord-006870-f5w6fw6q 249 28 BI BI NNP cord-006870-f5w6fw6q 249 29 , , , cord-006870-f5w6fw6q 249 30 Pre Pre NNP cord-006870-f5w6fw6q 249 31 - - JJ cord-006870-f5w6fw6q 249 32 or or CC cord-006870-f5w6fw6q 249 33 post post JJ cord-006870-f5w6fw6q 249 34 - - JJ cord-006870-f5w6fw6q 249 35 arrest arrest JJ cord-006870-f5w6fw6q 249 36 CPC CPC NNP cord-006870-f5w6fw6q 249 37 scores score NNS cord-006870-f5w6fw6q 249 38 . . . cord-006870-f5w6fw6q 250 1 Those those DT cord-006870-f5w6fw6q 250 2 responding respond VBG cord-006870-f5w6fw6q 250 3 that that IN cord-006870-f5w6fw6q 250 4 they -PRON- PRP cord-006870-f5w6fw6q 250 5 had have VBD cord-006870-f5w6fw6q 250 6 not not RB cord-006870-f5w6fw6q 250 7 made make VBN cord-006870-f5w6fw6q 250 8 a a DT cord-006870-f5w6fw6q 250 9 full full JJ cord-006870-f5w6fw6q 250 10 recovery recovery NN cord-006870-f5w6fw6q 250 11 had have VBD cord-006870-f5w6fw6q 250 12 higher high JJR cord-006870-f5w6fw6q 250 13 rates rate NNS cord-006870-f5w6fw6q 250 14 of of IN cord-006870-f5w6fw6q 250 15 PTSD PTSD NNP cord-006870-f5w6fw6q 250 16 - - HYPH cord-006870-f5w6fw6q 250 17 C C NNP cord-006870-f5w6fw6q 250 18 ( ( -LRB- cord-006870-f5w6fw6q 250 19 45 45 CD cord-006870-f5w6fw6q 250 20 % % NN cord-006870-f5w6fw6q 250 21 vs vs IN cord-006870-f5w6fw6q 250 22 0 0 CD cord-006870-f5w6fw6q 250 23 % % NN cord-006870-f5w6fw6q 250 24 , , , cord-006870-f5w6fw6q 250 25 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 250 26 ) ) -RRB- cord-006870-f5w6fw6q 250 27 , , , cord-006870-f5w6fw6q 250 28 and and CC cord-006870-f5w6fw6q 250 29 depression depression NN cord-006870-f5w6fw6q 250 30 ( ( -LRB- cord-006870-f5w6fw6q 250 31 51 51 CD cord-006870-f5w6fw6q 250 32 % % NN cord-006870-f5w6fw6q 250 33 vs vs IN cord-006870-f5w6fw6q 250 34 25 25 CD cord-006870-f5w6fw6q 250 35 % % NN cord-006870-f5w6fw6q 250 36 , , , cord-006870-f5w6fw6q 250 37 p=0.05 p=0.05 NNP cord-006870-f5w6fw6q 250 38 ) ) -RRB- cord-006870-f5w6fw6q 250 39 . . . cord-006870-f5w6fw6q 251 1 Moreover moreover RB cord-006870-f5w6fw6q 251 2 , , , cord-006870-f5w6fw6q 251 3 everyone everyone NN cord-006870-f5w6fw6q 251 4 that that IN cord-006870-f5w6fw6q 251 5 screened screen VBD cord-006870-f5w6fw6q 251 6 for for IN cord-006870-f5w6fw6q 251 7 PTSD PTSD NNP cord-006870-f5w6fw6q 251 8 ( ( -LRB- cord-006870-f5w6fw6q 251 9 N=19 N=19 NNP cord-006870-f5w6fw6q 251 10 ) ) -RRB- cord-006870-f5w6fw6q 251 11 reported report VBD cord-006870-f5w6fw6q 251 12 not not RB cord-006870-f5w6fw6q 251 13 having have VBG cord-006870-f5w6fw6q 251 14 made make VBN cord-006870-f5w6fw6q 251 15 a a DT cord-006870-f5w6fw6q 251 16 complete complete JJ cord-006870-f5w6fw6q 251 17 recovery recovery NN cord-006870-f5w6fw6q 251 18 . . . cord-006870-f5w6fw6q 252 1 Patients patient NNS cord-006870-f5w6fw6q 252 2 with with IN cord-006870-f5w6fw6q 252 3 higher high JJR cord-006870-f5w6fw6q 252 4 PTSD PTSD NNP cord-006870-f5w6fw6q 252 5 scores score NNS cord-006870-f5w6fw6q 252 6 were be VBD cord-006870-f5w6fw6q 252 7 more more RBR cord-006870-f5w6fw6q 252 8 likely likely JJ cord-006870-f5w6fw6q 252 9 to to TO cord-006870-f5w6fw6q 252 10 report report VB cord-006870-f5w6fw6q 252 11 not not RB cord-006870-f5w6fw6q 252 12 having have VBG cord-006870-f5w6fw6q 252 13 made make VBN cord-006870-f5w6fw6q 252 14 a a DT cord-006870-f5w6fw6q 252 15 complete complete JJ cord-006870-f5w6fw6q 252 16 recovery recovery NN cord-006870-f5w6fw6q 252 17 ( ( -LRB- cord-006870-f5w6fw6q 252 18 OR or CC cord-006870-f5w6fw6q 252 19 1.25 1.25 CD cord-006870-f5w6fw6q 252 20 ; ; : cord-006870-f5w6fw6q 252 21 p p NN cord-006870-f5w6fw6q 252 22 < < XX cord-006870-f5w6fw6q 252 23 0.003 0.003 CD cord-006870-f5w6fw6q 252 24 ) ) -RRB- cord-006870-f5w6fw6q 252 25 after after IN cord-006870-f5w6fw6q 252 26 adjusting adjust VBG cord-006870-f5w6fw6q 252 27 for for IN cord-006870-f5w6fw6q 252 28 age age NN cord-006870-f5w6fw6q 252 29 , , , cord-006870-f5w6fw6q 252 30 gender gender NN cord-006870-f5w6fw6q 252 31 and and CC cord-006870-f5w6fw6q 252 32 depression depression NN cord-006870-f5w6fw6q 252 33 scores score NNS cord-006870-f5w6fw6q 252 34 . . . cord-006870-f5w6fw6q 253 1 Presence presence NN cord-006870-f5w6fw6q 253 2 of of IN cord-006870-f5w6fw6q 253 3 post post JJ cord-006870-f5w6fw6q 253 4 traumatic traumatic JJ cord-006870-f5w6fw6q 253 5 stress stress NN cord-006870-f5w6fw6q 253 6 disorder disorder NN cord-006870-f5w6fw6q 253 7 symptomatology symptomatology NN cord-006870-f5w6fw6q 253 8 at at IN cord-006870-f5w6fw6q 253 9 discharge discharge NN cord-006870-f5w6fw6q 253 10 , , , cord-006870-f5w6fw6q 253 11 and and CC cord-006870-f5w6fw6q 253 12 not not RB cord-006870-f5w6fw6q 253 13 neurocognitive neurocognitive JJ cord-006870-f5w6fw6q 253 14 or or CC cord-006870-f5w6fw6q 253 15 functional functional JJ cord-006870-f5w6fw6q 253 16 status status NN cord-006870-f5w6fw6q 253 17 , , , cord-006870-f5w6fw6q 253 18 is be VBZ cord-006870-f5w6fw6q 253 19 highly highly RB cord-006870-f5w6fw6q 253 20 associated associate VBN cord-006870-f5w6fw6q 253 21 with with IN cord-006870-f5w6fw6q 253 22 post post JJ cord-006870-f5w6fw6q 253 23 - - JJ cord-006870-f5w6fw6q 253 24 cardiac cardiac JJ cord-006870-f5w6fw6q 253 25 arrest arrest NN cord-006870-f5w6fw6q 253 26 patients patient NNS cord-006870-f5w6fw6q 253 27 ' ' POS cord-006870-f5w6fw6q 253 28 subjective subjective JJ cord-006870-f5w6fw6q 253 29 perceptions perception NNS cord-006870-f5w6fw6q 253 30 of of IN cord-006870-f5w6fw6q 253 31 recovery recovery NN cord-006870-f5w6fw6q 253 32 . . . cord-006870-f5w6fw6q 254 1 Early early JJ cord-006870-f5w6fw6q 254 2 EEG EEG NNP cord-006870-f5w6fw6q 254 3 background background NN cord-006870-f5w6fw6q 254 4 reactivity reactivity NN cord-006870-f5w6fw6q 254 5 is be VBZ cord-006870-f5w6fw6q 254 6 a a DT cord-006870-f5w6fw6q 254 7 strong strong JJ cord-006870-f5w6fw6q 254 8 predictor predictor NN cord-006870-f5w6fw6q 254 9 of of IN cord-006870-f5w6fw6q 254 10 neurological neurological JJ cord-006870-f5w6fw6q 254 11 recovery recovery NN cord-006870-f5w6fw6q 254 12 after after IN cord-006870-f5w6fw6q 254 13 hypoxic hypoxic JJ cord-006870-f5w6fw6q 254 14 - - HYPH cord-006870-f5w6fw6q 254 15 ischemic ischemic JJ cord-006870-f5w6fw6q 254 16 brain brain NN cord-006870-f5w6fw6q 254 17 injury injury NN cord-006870-f5w6fw6q 254 18 despite despite IN cord-006870-f5w6fw6q 254 19 hypothermia hypothermia NN cord-006870-f5w6fw6q 254 20 and and CC cord-006870-f5w6fw6q 254 21 sedation sedation NN cord-006870-f5w6fw6q 254 22 . . . cord-006870-f5w6fw6q 255 1 Unfortunately unfortunately RB cord-006870-f5w6fw6q 255 2 , , , cord-006870-f5w6fw6q 255 3 expert expert JJ cord-006870-f5w6fw6q 255 4 interrater interrater NN cord-006870-f5w6fw6q 255 5 - - HYPH cord-006870-f5w6fw6q 255 6 agreement agreement NN cord-006870-f5w6fw6q 255 7 on on IN cord-006870-f5w6fw6q 255 8 visual visual JJ cord-006870-f5w6fw6q 255 9 scoring scoring NN cord-006870-f5w6fw6q 255 10 of of IN cord-006870-f5w6fw6q 255 11 EEG EEG NNP cord-006870-f5w6fw6q 255 12 background background NN cord-006870-f5w6fw6q 255 13 reactivity reactivity NN cord-006870-f5w6fw6q 255 14 ranges range VBZ cord-006870-f5w6fw6q 255 15 from from IN cord-006870-f5w6fw6q 255 16 24 24 CD cord-006870-f5w6fw6q 255 17 - - SYM cord-006870-f5w6fw6q 255 18 50 50 CD cord-006870-f5w6fw6q 255 19 % % NN cord-006870-f5w6fw6q 255 20 . . . cord-006870-f5w6fw6q 256 1 Recent recent JJ cord-006870-f5w6fw6q 256 2 studies study NNS cord-006870-f5w6fw6q 256 3 indicate indicate VBP cord-006870-f5w6fw6q 256 4 that that IN cord-006870-f5w6fw6q 256 5 machine machine NN cord-006870-f5w6fw6q 256 6 - - HYPH cord-006870-f5w6fw6q 256 7 learning learning NN cord-006870-f5w6fw6q 256 8 approaches approach NNS cord-006870-f5w6fw6q 256 9 using use VBG cord-006870-f5w6fw6q 256 10 quantitative quantitative JJ cord-006870-f5w6fw6q 256 11 EEG EEG NNP cord-006870-f5w6fw6q 256 12 ( ( -LRB- cord-006870-f5w6fw6q 256 13 QEEG QEEG NNP cord-006870-f5w6fw6q 256 14 ) ) -RRB- cord-006870-f5w6fw6q 256 15 might may MD cord-006870-f5w6fw6q 256 16 yield yield VB cord-006870-f5w6fw6q 256 17 equivalent equivalent JJ cord-006870-f5w6fw6q 256 18 or or CC cord-006870-f5w6fw6q 256 19 superior superior JJ cord-006870-f5w6fw6q 256 20 performance performance NN cord-006870-f5w6fw6q 256 21 to to IN cord-006870-f5w6fw6q 256 22 current current JJ cord-006870-f5w6fw6q 256 23 EEG EEG NNP cord-006870-f5w6fw6q 256 24 reactivity reactivity NN cord-006870-f5w6fw6q 256 25 assessment assessment NN cord-006870-f5w6fw6q 256 26 practices practice NNS cord-006870-f5w6fw6q 256 27 , , , cord-006870-f5w6fw6q 256 28 however however RB cord-006870-f5w6fw6q 256 29 its -PRON- PRP$ cord-006870-f5w6fw6q 256 30 ability ability NN cord-006870-f5w6fw6q 256 31 to to TO cord-006870-f5w6fw6q 256 32 predict predict VB cord-006870-f5w6fw6q 256 33 outcomes outcome NNS cord-006870-f5w6fw6q 256 34 has have VBZ cord-006870-f5w6fw6q 256 35 not not RB cord-006870-f5w6fw6q 256 36 been be VBN cord-006870-f5w6fw6q 256 37 tested test VBN cord-006870-f5w6fw6q 256 38 . . . cord-006870-f5w6fw6q 257 1 We -PRON- PRP cord-006870-f5w6fw6q 257 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 257 3 that that IN cord-006870-f5w6fw6q 257 4 a a DT cord-006870-f5w6fw6q 257 5 QEEG QEEG NNP cord-006870-f5w6fw6q 257 6 reactivity reactivity NN cord-006870-f5w6fw6q 257 7 method method NN cord-006870-f5w6fw6q 257 8 can can MD cord-006870-f5w6fw6q 257 9 predict predict VB cord-006870-f5w6fw6q 257 10 long long JJ cord-006870-f5w6fw6q 257 11 - - HYPH cord-006870-f5w6fw6q 257 12 term term NN cord-006870-f5w6fw6q 257 13 functional functional JJ cord-006870-f5w6fw6q 257 14 outcome outcome NN cord-006870-f5w6fw6q 257 15 in in IN cord-006870-f5w6fw6q 257 16 hypoxic hypoxic JJ cord-006870-f5w6fw6q 257 17 ischemic ischemic JJ cord-006870-f5w6fw6q 257 18 brain brain NN cord-006870-f5w6fw6q 257 19 injury injury NN cord-006870-f5w6fw6q 257 20 . . . cord-006870-f5w6fw6q 258 1 We -PRON- PRP cord-006870-f5w6fw6q 258 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 258 3 reviewed review VBD cord-006870-f5w6fw6q 258 4 clinical clinical JJ cord-006870-f5w6fw6q 258 5 and and CC cord-006870-f5w6fw6q 258 6 EEG EEG NNP cord-006870-f5w6fw6q 258 7 data datum NNS cord-006870-f5w6fw6q 258 8 of of IN cord-006870-f5w6fw6q 258 9 cardiac cardiac JJ cord-006870-f5w6fw6q 258 10 arrest arrest NN cord-006870-f5w6fw6q 258 11 patients patient NNS cord-006870-f5w6fw6q 258 12 managed manage VBD cord-006870-f5w6fw6q 258 13 with with IN cord-006870-f5w6fw6q 258 14 hypothermia hypothermia NN cord-006870-f5w6fw6q 258 15 at at IN cord-006870-f5w6fw6q 258 16 two two CD cord-006870-f5w6fw6q 258 17 university university NN cord-006870-f5w6fw6q 258 18 hospitals hospital NNS cord-006870-f5w6fw6q 258 19 . . . cord-006870-f5w6fw6q 259 1 EEG EEG NNP cord-006870-f5w6fw6q 259 2 reactivity reactivity NN cord-006870-f5w6fw6q 259 3 was be VBD cord-006870-f5w6fw6q 259 4 tested test VBN cord-006870-f5w6fw6q 259 5 daily daily RB cord-006870-f5w6fw6q 259 6 using use VBG cord-006870-f5w6fw6q 259 7 a a DT cord-006870-f5w6fw6q 259 8 structured structured JJ cord-006870-f5w6fw6q 259 9 exam exam NN cord-006870-f5w6fw6q 259 10 consisting consist VBG cord-006870-f5w6fw6q 259 11 of of IN cord-006870-f5w6fw6q 259 12 auditory auditory JJ cord-006870-f5w6fw6q 259 13 , , , cord-006870-f5w6fw6q 259 14 tactile tactile JJ cord-006870-f5w6fw6q 259 15 , , , cord-006870-f5w6fw6q 259 16 and and CC cord-006870-f5w6fw6q 259 17 visual visual JJ cord-006870-f5w6fw6q 259 18 stimulation stimulation NN cord-006870-f5w6fw6q 259 19 . . . cord-006870-f5w6fw6q 260 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 260 2 quantitative quantitative JJ cord-006870-f5w6fw6q 260 3 EEG EEG NNP cord-006870-f5w6fw6q 260 4 method method NN cord-006870-f5w6fw6q 260 5 evaluated evaluate VBD cord-006870-f5w6fw6q 260 6 changes change NNS cord-006870-f5w6fw6q 260 7 in in IN cord-006870-f5w6fw6q 260 8 EEG EEG NNP cord-006870-f5w6fw6q 260 9 spectra spectrum NNS cord-006870-f5w6fw6q 260 10 , , , cord-006870-f5w6fw6q 260 11 entropy entropy NN cord-006870-f5w6fw6q 260 12 , , , cord-006870-f5w6fw6q 260 13 and and CC cord-006870-f5w6fw6q 260 14 frequency frequency NN cord-006870-f5w6fw6q 260 15 features feature NNS cord-006870-f5w6fw6q 260 16 during during IN cord-006870-f5w6fw6q 260 17 30 30 CD cord-006870-f5w6fw6q 260 18 seconds second NNS cord-006870-f5w6fw6q 260 19 before before RB cord-006870-f5w6fw6q 260 20 and and CC cord-006870-f5w6fw6q 260 21 after after IN cord-006870-f5w6fw6q 260 22 each each DT cord-006870-f5w6fw6q 260 23 stimulation stimulation NN cord-006870-f5w6fw6q 260 24 - - HYPH cord-006870-f5w6fw6q 260 25 step step NN cord-006870-f5w6fw6q 260 26 ( ( -LRB- cord-006870-f5w6fw6q 260 27 30 30 CD cord-006870-f5w6fw6q 260 28 QEEG QEEG NNP cord-006870-f5w6fw6q 260 29 features feature NNS cord-006870-f5w6fw6q 260 30 used use VBN cord-006870-f5w6fw6q 260 31 ) ) -RRB- cord-006870-f5w6fw6q 260 32 . . . cord-006870-f5w6fw6q 261 1 Only only RB cord-006870-f5w6fw6q 261 2 the the DT cord-006870-f5w6fw6q 261 3 first first JJ cord-006870-f5w6fw6q 261 4 EEG EEG NNP cord-006870-f5w6fw6q 261 5 reactivity reactivity NN cord-006870-f5w6fw6q 261 6 assessment assessment NN cord-006870-f5w6fw6q 261 7 for for IN cord-006870-f5w6fw6q 261 8 each each DT cord-006870-f5w6fw6q 261 9 subject subject NN cord-006870-f5w6fw6q 261 10 was be VBD cord-006870-f5w6fw6q 261 11 used use VBN cord-006870-f5w6fw6q 261 12 in in IN cord-006870-f5w6fw6q 261 13 the the DT cord-006870-f5w6fw6q 261 14 final final JJ cord-006870-f5w6fw6q 261 15 analysis analysis NN cord-006870-f5w6fw6q 261 16 . . . cord-006870-f5w6fw6q 262 1 Good good JJ cord-006870-f5w6fw6q 262 2 outcome outcome NN cord-006870-f5w6fw6q 262 3 was be VBD cord-006870-f5w6fw6q 262 4 defined define VBN cord-006870-f5w6fw6q 262 5 as as IN cord-006870-f5w6fw6q 262 6 Cerebral Cerebral NNP cord-006870-f5w6fw6q 262 7 Performance Performance NNP cord-006870-f5w6fw6q 262 8 Category Category NNP cord-006870-f5w6fw6q 262 9 of of IN cord-006870-f5w6fw6q 262 10 1 1 CD cord-006870-f5w6fw6q 262 11 - - SYM cord-006870-f5w6fw6q 262 12 2 2 CD cord-006870-f5w6fw6q 262 13 at at IN cord-006870-f5w6fw6q 262 14 six six CD cord-006870-f5w6fw6q 262 15 months month NNS cord-006870-f5w6fw6q 262 16 . . . cord-006870-f5w6fw6q 263 1 A a DT cord-006870-f5w6fw6q 263 2 penalized penalize VBN cord-006870-f5w6fw6q 263 3 multinomial multinomial JJ cord-006870-f5w6fw6q 263 4 logistic logistic JJ cord-006870-f5w6fw6q 263 5 regression regression NN cord-006870-f5w6fw6q 263 6 was be VBD cord-006870-f5w6fw6q 263 7 utilized utilize VBN cord-006870-f5w6fw6q 263 8 for for IN cord-006870-f5w6fw6q 263 9 feature feature NN cord-006870-f5w6fw6q 263 10 selection selection NN cord-006870-f5w6fw6q 263 11 and and CC cord-006870-f5w6fw6q 263 12 a a DT cord-006870-f5w6fw6q 263 13 random random JJ cord-006870-f5w6fw6q 263 14 - - HYPH cord-006870-f5w6fw6q 263 15 forest forest NN cord-006870-f5w6fw6q 263 16 classifier classifier NN cord-006870-f5w6fw6q 263 17 was be VBD cord-006870-f5w6fw6q 263 18 employed employ VBN cord-006870-f5w6fw6q 263 19 in in IN cord-006870-f5w6fw6q 263 20 the the DT cord-006870-f5w6fw6q 263 21 training training NN cord-006870-f5w6fw6q 263 22 and and CC cord-006870-f5w6fw6q 263 23 validation validation NN cord-006870-f5w6fw6q 263 24 sets set NNS cord-006870-f5w6fw6q 263 25 . . . cord-006870-f5w6fw6q 264 1 Model model NN cord-006870-f5w6fw6q 264 2 performance performance NN cord-006870-f5w6fw6q 264 3 evaluation evaluation NN cord-006870-f5w6fw6q 264 4 metric metric NN cord-006870-f5w6fw6q 264 5 was be VBD cord-006870-f5w6fw6q 264 6 the the DT cord-006870-f5w6fw6q 264 7 area area NN cord-006870-f5w6fw6q 264 8 under under IN cord-006870-f5w6fw6q 264 9 ROC ROC NNP cord-006870-f5w6fw6q 264 10 curve curve NN cord-006870-f5w6fw6q 264 11 ( ( -LRB- cord-006870-f5w6fw6q 264 12 AUC AUC NNP cord-006870-f5w6fw6q 264 13 ) ) -RRB- cord-006870-f5w6fw6q 264 14 . . . cord-006870-f5w6fw6q 265 1 Outcome outcome NN cord-006870-f5w6fw6q 265 2 and and CC cord-006870-f5w6fw6q 265 3 EEG EEG NNP cord-006870-f5w6fw6q 265 4 data datum NNS cord-006870-f5w6fw6q 265 5 was be VBD cord-006870-f5w6fw6q 265 6 available available JJ cord-006870-f5w6fw6q 265 7 for for IN cord-006870-f5w6fw6q 265 8 a a DT cord-006870-f5w6fw6q 265 9 total total JJ cord-006870-f5w6fw6q 265 10 77 77 CD cord-006870-f5w6fw6q 265 11 subjects subject NNS cord-006870-f5w6fw6q 265 12 , , , cord-006870-f5w6fw6q 265 13 and and CC cord-006870-f5w6fw6q 265 14 30 30 CD cord-006870-f5w6fw6q 265 15 cases case NNS cord-006870-f5w6fw6q 265 16 were be VBD cord-006870-f5w6fw6q 265 17 excluded exclude VBN cord-006870-f5w6fw6q 265 18 due due IN cord-006870-f5w6fw6q 265 19 to to IN cord-006870-f5w6fw6q 265 20 presence presence NN cord-006870-f5w6fw6q 265 21 of of IN cord-006870-f5w6fw6q 265 22 burst burst NN cord-006870-f5w6fw6q 265 23 - - HYPH cord-006870-f5w6fw6q 265 24 suppression suppression NN cord-006870-f5w6fw6q 265 25 , , , cord-006870-f5w6fw6q 265 26 periodic periodic JJ cord-006870-f5w6fw6q 265 27 epileptiform epileptiform NN cord-006870-f5w6fw6q 265 28 discharges discharge NNS cord-006870-f5w6fw6q 265 29 , , , cord-006870-f5w6fw6q 265 30 or or CC cord-006870-f5w6fw6q 265 31 EEG EEG NNP cord-006870-f5w6fw6q 265 32 artifact artifact NN cord-006870-f5w6fw6q 265 33 . . . cord-006870-f5w6fw6q 266 1 Forty forty CD cord-006870-f5w6fw6q 266 2 - - HYPH cord-006870-f5w6fw6q 266 3 seven seven CD cord-006870-f5w6fw6q 266 4 subjects subject NNS cord-006870-f5w6fw6q 266 5 were be VBD cord-006870-f5w6fw6q 266 6 included include VBN cord-006870-f5w6fw6q 266 7 in in IN cord-006870-f5w6fw6q 266 8 the the DT cord-006870-f5w6fw6q 266 9 final final JJ cord-006870-f5w6fw6q 266 10 analysis analysis NN cord-006870-f5w6fw6q 266 11 . . . cord-006870-f5w6fw6q 267 1 Mean mean JJ cord-006870-f5w6fw6q 267 2 age age NN cord-006870-f5w6fw6q 267 3 was be VBD cord-006870-f5w6fw6q 267 4 57.8 57.8 CD cord-006870-f5w6fw6q 267 5 ( ( -LRB- cord-006870-f5w6fw6q 267 6 standard standard JJ cord-006870-f5w6fw6q 267 7 deviation deviation NN cord-006870-f5w6fw6q 267 8 17.9 17.9 CD cord-006870-f5w6fw6q 267 9 ) ) -RRB- cord-006870-f5w6fw6q 267 10 years year NNS cord-006870-f5w6fw6q 267 11 and and CC cord-006870-f5w6fw6q 267 12 29.8 29.8 CD cord-006870-f5w6fw6q 267 13 % % NN cord-006870-f5w6fw6q 267 14 had have VBD cord-006870-f5w6fw6q 267 15 good good JJ cord-006870-f5w6fw6q 267 16 outcome outcome NN cord-006870-f5w6fw6q 267 17 . . . cord-006870-f5w6fw6q 268 1 The the DT cord-006870-f5w6fw6q 268 2 combination combination NN cord-006870-f5w6fw6q 268 3 of of IN cord-006870-f5w6fw6q 268 4 four four CD cord-006870-f5w6fw6q 268 5 features feature NNS cord-006870-f5w6fw6q 268 6 provided provide VBN cord-006870-f5w6fw6q 268 7 best good JJS cord-006870-f5w6fw6q 268 8 outcome outcome NN cord-006870-f5w6fw6q 268 9 prediction prediction NN cord-006870-f5w6fw6q 268 10 performance performance NN cord-006870-f5w6fw6q 268 11 with with IN cord-006870-f5w6fw6q 268 12 an an DT cord-006870-f5w6fw6q 268 13 AUC AUC NNP cord-006870-f5w6fw6q 268 14 of of IN cord-006870-f5w6fw6q 268 15 0.87 0.87 CD cord-006870-f5w6fw6q 268 16 ( ( -LRB- cord-006870-f5w6fw6q 268 17 Kolmogorov Kolmogorov NNP cord-006870-f5w6fw6q 268 18 - - HYPH cord-006870-f5w6fw6q 268 19 Smirnov Smirnov NNP cord-006870-f5w6fw6q 268 20 test test NN cord-006870-f5w6fw6q 268 21 , , , cord-006870-f5w6fw6q 268 22 skewness skewness NN cord-006870-f5w6fw6q 268 23 , , , cord-006870-f5w6fw6q 268 24 Two two CD cord-006870-f5w6fw6q 268 25 - - HYPH cord-006870-f5w6fw6q 268 26 group group NN cord-006870-f5w6fw6q 268 27 test test NN cord-006870-f5w6fw6q 268 28 , , , cord-006870-f5w6fw6q 268 29 and and CC cord-006870-f5w6fw6q 268 30 Renyi Renyi NNP cord-006870-f5w6fw6q 268 31 entropy entropy NN cord-006870-f5w6fw6q 268 32 ) ) -RRB- cord-006870-f5w6fw6q 268 33 . . . cord-006870-f5w6fw6q 269 1 Early early JJ cord-006870-f5w6fw6q 269 2 QEEG QEEG NNP cord-006870-f5w6fw6q 269 3 reactivity reactivity NN cord-006870-f5w6fw6q 269 4 is be VBZ cord-006870-f5w6fw6q 269 5 predictive predictive JJ cord-006870-f5w6fw6q 269 6 of of IN cord-006870-f5w6fw6q 269 7 good good JJ cord-006870-f5w6fw6q 269 8 outcome outcome NN cord-006870-f5w6fw6q 269 9 at at IN cord-006870-f5w6fw6q 269 10 six six CD cord-006870-f5w6fw6q 269 11 months month NNS cord-006870-f5w6fw6q 269 12 . . . cord-006870-f5w6fw6q 270 1 A a DT cord-006870-f5w6fw6q 270 2 quantitative quantitative JJ cord-006870-f5w6fw6q 270 3 approach approach NN cord-006870-f5w6fw6q 270 4 to to IN cord-006870-f5w6fw6q 270 5 EEG EEG NNP cord-006870-f5w6fw6q 270 6 reactivity reactivity NN cord-006870-f5w6fw6q 270 7 analysis analysis NN cord-006870-f5w6fw6q 270 8 might may MD cord-006870-f5w6fw6q 270 9 facilitate facilitate VB cord-006870-f5w6fw6q 270 10 accurate accurate JJ cord-006870-f5w6fw6q 270 11 and and CC cord-006870-f5w6fw6q 270 12 individualized individualized JJ cord-006870-f5w6fw6q 270 13 prognostication prognostication NN cord-006870-f5w6fw6q 270 14 in in IN cord-006870-f5w6fw6q 270 15 hypoxic hypoxic JJ cord-006870-f5w6fw6q 270 16 - - HYPH cord-006870-f5w6fw6q 270 17 ischemic ischemic JJ cord-006870-f5w6fw6q 270 18 brain brain NN cord-006870-f5w6fw6q 270 19 injury injury NN cord-006870-f5w6fw6q 270 20 . . . cord-006870-f5w6fw6q 271 1 Hypoxic hypoxic JJ cord-006870-f5w6fw6q 271 2 - - HYPH cord-006870-f5w6fw6q 271 3 ischemic ischemic JJ cord-006870-f5w6fw6q 271 4 brain brain NN cord-006870-f5w6fw6q 271 5 injury injury NN cord-006870-f5w6fw6q 271 6 is be VBZ cord-006870-f5w6fw6q 271 7 the the DT cord-006870-f5w6fw6q 271 8 leading leading JJ cord-006870-f5w6fw6q 271 9 cause cause NN cord-006870-f5w6fw6q 271 10 of of IN cord-006870-f5w6fw6q 271 11 morbidity morbidity NN cord-006870-f5w6fw6q 271 12 and and CC cord-006870-f5w6fw6q 271 13 mortality mortality NN cord-006870-f5w6fw6q 271 14 following follow VBG cord-006870-f5w6fw6q 271 15 cardiac cardiac JJ cord-006870-f5w6fw6q 271 16 arrest arrest NN cord-006870-f5w6fw6q 271 17 , , , cord-006870-f5w6fw6q 271 18 and and CC cord-006870-f5w6fw6q 271 19 the the DT cord-006870-f5w6fw6q 271 20 ability ability NN cord-006870-f5w6fw6q 271 21 to to TO cord-006870-f5w6fw6q 271 22 predict predict VB cord-006870-f5w6fw6q 271 23 neurologic neurologic JJ cord-006870-f5w6fw6q 271 24 recovery recovery NN cord-006870-f5w6fw6q 271 25 in in IN cord-006870-f5w6fw6q 271 26 comatose comatose JJ cord-006870-f5w6fw6q 271 27 cardiac cardiac JJ cord-006870-f5w6fw6q 271 28 arrest arrest NN cord-006870-f5w6fw6q 271 29 survivors survivor NNS cord-006870-f5w6fw6q 271 30 is be VBZ cord-006870-f5w6fw6q 271 31 limited limited JJ cord-006870-f5w6fw6q 271 32 . . . cord-006870-f5w6fw6q 272 1 Functional functional JJ cord-006870-f5w6fw6q 272 2 MRI MRI NNP cord-006870-f5w6fw6q 272 3 measures measure NNS cord-006870-f5w6fw6q 272 4 brain brain NN cord-006870-f5w6fw6q 272 5 network network NN cord-006870-f5w6fw6q 272 6 connectivity connectivity NN cord-006870-f5w6fw6q 272 7 and and CC cord-006870-f5w6fw6q 272 8 resting rest VBG cord-006870-f5w6fw6q 272 9 - - HYPH cord-006870-f5w6fw6q 272 10 state state NN cord-006870-f5w6fw6q 272 11 network network NN cord-006870-f5w6fw6q 272 12 connectivity connectivity NN cord-006870-f5w6fw6q 272 13 can can MD cord-006870-f5w6fw6q 272 14 be be VB cord-006870-f5w6fw6q 272 15 measured measure VBN cord-006870-f5w6fw6q 272 16 in in IN cord-006870-f5w6fw6q 272 17 comatose comatose JJ cord-006870-f5w6fw6q 272 18 patients patient NNS cord-006870-f5w6fw6q 272 19 . . . cord-006870-f5w6fw6q 273 1 The the DT cord-006870-f5w6fw6q 273 2 default default NN cord-006870-f5w6fw6q 273 3 mode mode NN cord-006870-f5w6fw6q 273 4 network network NN cord-006870-f5w6fw6q 273 5 ( ( -LRB- cord-006870-f5w6fw6q 273 6 DMN DMN NNP cord-006870-f5w6fw6q 273 7 ) ) -RRB- cord-006870-f5w6fw6q 273 8 is be VBZ cord-006870-f5w6fw6q 273 9 one one CD cord-006870-f5w6fw6q 273 10 resting rest VBG cord-006870-f5w6fw6q 273 11 state state NN cord-006870-f5w6fw6q 273 12 network network NN cord-006870-f5w6fw6q 273 13 that that WDT cord-006870-f5w6fw6q 273 14 has have VBZ cord-006870-f5w6fw6q 273 15 been be VBN cord-006870-f5w6fw6q 273 16 correlated correlate VBN cord-006870-f5w6fw6q 273 17 with with IN cord-006870-f5w6fw6q 273 18 consciousness consciousness NN cord-006870-f5w6fw6q 273 19 . . . cord-006870-f5w6fw6q 274 1 We -PRON- PRP cord-006870-f5w6fw6q 274 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 274 3 the the DT cord-006870-f5w6fw6q 274 4 degree degree NN cord-006870-f5w6fw6q 274 5 of of IN cord-006870-f5w6fw6q 274 6 connectivity connectivity NN cord-006870-f5w6fw6q 274 7 in in IN cord-006870-f5w6fw6q 274 8 the the DT cord-006870-f5w6fw6q 274 9 DMN DMN NNP cord-006870-f5w6fw6q 274 10 and and CC cord-006870-f5w6fw6q 274 11 other other JJ cord-006870-f5w6fw6q 274 12 resting rest VBG cord-006870-f5w6fw6q 274 13 - - HYPH cord-006870-f5w6fw6q 274 14 state state NN cord-006870-f5w6fw6q 274 15 networks network NNS cord-006870-f5w6fw6q 274 16 would would MD cord-006870-f5w6fw6q 274 17 correlate correlate VB cord-006870-f5w6fw6q 274 18 with with IN cord-006870-f5w6fw6q 274 19 consciousness consciousness NN cord-006870-f5w6fw6q 274 20 recovery recovery NN cord-006870-f5w6fw6q 274 21 in in IN cord-006870-f5w6fw6q 274 22 post post JJ cord-006870-f5w6fw6q 274 23 - - JJ cord-006870-f5w6fw6q 274 24 cardiac cardiac JJ cord-006870-f5w6fw6q 274 25 arrest arrest NN cord-006870-f5w6fw6q 274 26 coma coma NN cord-006870-f5w6fw6q 274 27 . . . cord-006870-f5w6fw6q 275 1 Consecutive consecutive JJ cord-006870-f5w6fw6q 275 2 patients patient NNS cord-006870-f5w6fw6q 275 3 with with IN cord-006870-f5w6fw6q 275 4 hypoxic hypoxic JJ cord-006870-f5w6fw6q 275 5 - - HYPH cord-006870-f5w6fw6q 275 6 ischemic ischemic JJ cord-006870-f5w6fw6q 275 7 coma coma NN cord-006870-f5w6fw6q 275 8 were be VBD cord-006870-f5w6fw6q 275 9 enrolled enrol VBN cord-006870-f5w6fw6q 275 10 . . . cord-006870-f5w6fw6q 276 1 Functional functional JJ cord-006870-f5w6fw6q 276 2 MRI MRI NNP cord-006870-f5w6fw6q 276 3 was be VBD cord-006870-f5w6fw6q 276 4 obtained obtain VBN cord-006870-f5w6fw6q 276 5 on on IN cord-006870-f5w6fw6q 276 6 all all DT cord-006870-f5w6fw6q 276 7 patients patient NNS cord-006870-f5w6fw6q 276 8 on on IN cord-006870-f5w6fw6q 276 9 post post JJ cord-006870-f5w6fw6q 276 10 - - JJ cord-006870-f5w6fw6q 276 11 arrest arrest JJ cord-006870-f5w6fw6q 276 12 day day NN cord-006870-f5w6fw6q 276 13 2 2 CD cord-006870-f5w6fw6q 276 14 - - SYM cord-006870-f5w6fw6q 276 15 5 5 CD cord-006870-f5w6fw6q 276 16 on on IN cord-006870-f5w6fw6q 276 17 an an DT cord-006870-f5w6fw6q 276 18 inpatient inpatient JJ cord-006870-f5w6fw6q 276 19 3 3 CD cord-006870-f5w6fw6q 276 20 Tesla Tesla NNP cord-006870-f5w6fw6q 276 21 MRI MRI NNP cord-006870-f5w6fw6q 276 22 . . . cord-006870-f5w6fw6q 277 1 The the DT cord-006870-f5w6fw6q 277 2 connectivity connectivity NN cord-006870-f5w6fw6q 277 3 in in IN cord-006870-f5w6fw6q 277 4 multiple multiple JJ cord-006870-f5w6fw6q 277 5 resting rest VBG cord-006870-f5w6fw6q 277 6 - - HYPH cord-006870-f5w6fw6q 277 7 state state NN cord-006870-f5w6fw6q 277 8 networks network NNS cord-006870-f5w6fw6q 277 9 was be VBD cord-006870-f5w6fw6q 277 10 analyzed analyze VBN cord-006870-f5w6fw6q 277 11 using use VBG cord-006870-f5w6fw6q 277 12 Pearson Pearson NNP cord-006870-f5w6fw6q 277 13 's 's POS cord-006870-f5w6fw6q 277 14 correlations correlation NNS cord-006870-f5w6fw6q 277 15 between between IN cord-006870-f5w6fw6q 277 16 30 30 CD cord-006870-f5w6fw6q 277 17 component component NN cord-006870-f5w6fw6q 277 18 maps map NNS cord-006870-f5w6fw6q 277 19 for for IN cord-006870-f5w6fw6q 277 20 each each DT cord-006870-f5w6fw6q 277 21 subject subject NN cord-006870-f5w6fw6q 277 22 and and CC cord-006870-f5w6fw6q 277 23 14 14 CD cord-006870-f5w6fw6q 277 24 previously previously RB cord-006870-f5w6fw6q 277 25 defined define VBN cord-006870-f5w6fw6q 277 26 standard standard JJ cord-006870-f5w6fw6q 277 27 network network NN cord-006870-f5w6fw6q 277 28 maps map NNS cord-006870-f5w6fw6q 277 29 . . . cord-006870-f5w6fw6q 278 1 Connectivity connectivity NN cord-006870-f5w6fw6q 278 2 in in IN cord-006870-f5w6fw6q 278 3 the the DT cord-006870-f5w6fw6q 278 4 default default NN cord-006870-f5w6fw6q 278 5 mode mode NN cord-006870-f5w6fw6q 278 6 network network NN cord-006870-f5w6fw6q 278 7 and and CC cord-006870-f5w6fw6q 278 8 in in IN cord-006870-f5w6fw6q 278 9 additional additional JJ cord-006870-f5w6fw6q 278 10 resting rest VBG cord-006870-f5w6fw6q 278 11 - - HYPH cord-006870-f5w6fw6q 278 12 state state NN cord-006870-f5w6fw6q 278 13 networks network NNS cord-006870-f5w6fw6q 278 14 was be VBD cord-006870-f5w6fw6q 278 15 correlated correlate VBN cord-006870-f5w6fw6q 278 16 with with IN cord-006870-f5w6fw6q 278 17 outcome outcome NN cord-006870-f5w6fw6q 278 18 . . . cord-006870-f5w6fw6q 279 1 Good good JJ cord-006870-f5w6fw6q 279 2 outcome outcome NN cord-006870-f5w6fw6q 279 3 was be VBD cord-006870-f5w6fw6q 279 4 defined define VBN cord-006870-f5w6fw6q 279 5 as as IN cord-006870-f5w6fw6q 279 6 consciousness consciousness NN cord-006870-f5w6fw6q 279 7 recovery recovery NN cord-006870-f5w6fw6q 279 8 at at IN cord-006870-f5w6fw6q 279 9 any any DT cord-006870-f5w6fw6q 279 10 point point NN cord-006870-f5w6fw6q 279 11 in in IN cord-006870-f5w6fw6q 279 12 the the DT cord-006870-f5w6fw6q 279 13 acute acute JJ cord-006870-f5w6fw6q 279 14 hospitalization hospitalization NN cord-006870-f5w6fw6q 279 15 . . . cord-006870-f5w6fw6q 280 1 15 15 CD cord-006870-f5w6fw6q 280 2 patients patient NNS cord-006870-f5w6fw6q 280 3 were be VBD cord-006870-f5w6fw6q 280 4 included include VBN cord-006870-f5w6fw6q 280 5 in in IN cord-006870-f5w6fw6q 280 6 this this DT cord-006870-f5w6fw6q 280 7 study study NN cord-006870-f5w6fw6q 280 8 . . . cord-006870-f5w6fw6q 281 1 The the DT cord-006870-f5w6fw6q 281 2 mean mean JJ cord-006870-f5w6fw6q 281 3 age age NN cord-006870-f5w6fw6q 281 4 was be VBD cord-006870-f5w6fw6q 281 5 57±14 57±14 CD cord-006870-f5w6fw6q 281 6 years year NNS cord-006870-f5w6fw6q 281 7 ( ( -LRB- cord-006870-f5w6fw6q 281 8 22 22 CD cord-006870-f5w6fw6q 281 9 - - SYM cord-006870-f5w6fw6q 281 10 79 79 CD cord-006870-f5w6fw6q 281 11 ) ) -RRB- cord-006870-f5w6fw6q 281 12 and and CC cord-006870-f5w6fw6q 281 13 9 9 CD cord-006870-f5w6fw6q 281 14 were be VBD cord-006870-f5w6fw6q 281 15 male male JJ cord-006870-f5w6fw6q 281 16 . . . cord-006870-f5w6fw6q 282 1 6 6 CD cord-006870-f5w6fw6q 282 2 patients patient NNS cord-006870-f5w6fw6q 282 3 survived survive VBD cord-006870-f5w6fw6q 282 4 with with IN cord-006870-f5w6fw6q 282 5 good good JJ cord-006870-f5w6fw6q 282 6 outcome outcome NN cord-006870-f5w6fw6q 282 7 . . . cord-006870-f5w6fw6q 283 1 The the DT cord-006870-f5w6fw6q 283 2 primary primary JJ cord-006870-f5w6fw6q 283 3 arrest arrest NN cord-006870-f5w6fw6q 283 4 rhythm rhythm NN cord-006870-f5w6fw6q 283 5 and and CC cord-006870-f5w6fw6q 283 6 the the DT cord-006870-f5w6fw6q 283 7 duration duration NN cord-006870-f5w6fw6q 283 8 of of IN cord-006870-f5w6fw6q 283 9 cardiac cardiac JJ cord-006870-f5w6fw6q 283 10 arrest arrest NN cord-006870-f5w6fw6q 283 11 did do VBD cord-006870-f5w6fw6q 283 12 not not RB cord-006870-f5w6fw6q 283 13 differ differ VB cord-006870-f5w6fw6q 283 14 between between IN cord-006870-f5w6fw6q 283 15 groups group NNS cord-006870-f5w6fw6q 283 16 ( ( -LRB- cord-006870-f5w6fw6q 283 17 primary primary JJ cord-006870-f5w6fw6q 283 18 rhythm rhythm NN cord-006870-f5w6fw6q 283 19 as as IN cord-006870-f5w6fw6q 283 20 VT VT NNP cord-006870-f5w6fw6q 283 21 / / SYM cord-006870-f5w6fw6q 283 22 VF VF NNP cord-006870-f5w6fw6q 283 23 : : : cord-006870-f5w6fw6q 283 24 50 50 CD cord-006870-f5w6fw6q 283 25 % % NN cord-006870-f5w6fw6q 283 26 vs vs IN cord-006870-f5w6fw6q 283 27 44 44 CD cord-006870-f5w6fw6q 283 28 % % NN cord-006870-f5w6fw6q 283 29 , , , cord-006870-f5w6fw6q 283 30 good good JJ cord-006870-f5w6fw6q 283 31 vs vs IN cord-006870-f5w6fw6q 283 32 poor poor JJ cord-006870-f5w6fw6q 283 33 , , , cord-006870-f5w6fw6q 283 34 p= p= JJ cord-006870-f5w6fw6q 283 35 0.8 0.8 CD cord-006870-f5w6fw6q 283 36 ; ; : cord-006870-f5w6fw6q 283 37 cardiac cardiac JJ cord-006870-f5w6fw6q 283 38 arrest arrest NN cord-006870-f5w6fw6q 283 39 duration duration NN cord-006870-f5w6fw6q 283 40 : : : cord-006870-f5w6fw6q 283 41 20.2±11.7 20.2±11.7 CD cord-006870-f5w6fw6q 283 42 minutes minute NNS cord-006870-f5w6fw6q 283 43 vs vs IN cord-006870-f5w6fw6q 283 44 20.2±12.1 20.2±12.1 CD cord-006870-f5w6fw6q 283 45 minutes minute NNS cord-006870-f5w6fw6q 283 46 , , , cord-006870-f5w6fw6q 283 47 good good JJ cord-006870-f5w6fw6q 283 48 vs vs IN cord-006870-f5w6fw6q 283 49 poor poor JJ cord-006870-f5w6fw6q 283 50 , , , cord-006870-f5w6fw6q 283 51 p=0.99 p=0.99 NNP cord-006870-f5w6fw6q 283 52 ) ) -RRB- cord-006870-f5w6fw6q 283 53 . . . cord-006870-f5w6fw6q 284 1 Patients patient NNS cord-006870-f5w6fw6q 284 2 with with IN cord-006870-f5w6fw6q 284 3 good good JJ cord-006870-f5w6fw6q 284 4 outcome outcome NN cord-006870-f5w6fw6q 284 5 had have VBD cord-006870-f5w6fw6q 284 6 significantly significantly RB cord-006870-f5w6fw6q 284 7 higher high JJR cord-006870-f5w6fw6q 284 8 mean mean JJ cord-006870-f5w6fw6q 284 9 network network NN cord-006870-f5w6fw6q 284 10 connectivity connectivity NN cord-006870-f5w6fw6q 284 11 ( ( -LRB- cord-006870-f5w6fw6q 284 12 0.13±0.06 0.13±0.06 CD cord-006870-f5w6fw6q 284 13 vs vs IN cord-006870-f5w6fw6q 284 14 0.07±0.04 0.07±0.04 CD cord-006870-f5w6fw6q 284 15 , , , cord-006870-f5w6fw6q 284 16 good good JJ cord-006870-f5w6fw6q 284 17 vs vs IN cord-006870-f5w6fw6q 284 18 poor poor JJ cord-006870-f5w6fw6q 284 19 , , , cord-006870-f5w6fw6q 284 20 p=0.03 p=0.03 NNP cord-006870-f5w6fw6q 284 21 ) ) -RRB- cord-006870-f5w6fw6q 284 22 . . . cord-006870-f5w6fw6q 285 1 DMN DMN NNP cord-006870-f5w6fw6q 285 2 connectivity connectivity NN cord-006870-f5w6fw6q 285 3 showed show VBD cord-006870-f5w6fw6q 285 4 a a DT cord-006870-f5w6fw6q 285 5 trend trend NN cord-006870-f5w6fw6q 285 6 towards towards IN cord-006870-f5w6fw6q 285 7 significance significance NN cord-006870-f5w6fw6q 285 8 ( ( -LRB- cord-006870-f5w6fw6q 285 9 0.14±0.04 0.14±0.04 CD cord-006870-f5w6fw6q 285 10 vs vs IN cord-006870-f5w6fw6q 285 11 0.09±0.06 0.09±0.06 CD cord-006870-f5w6fw6q 285 12 , , , cord-006870-f5w6fw6q 285 13 good good JJ cord-006870-f5w6fw6q 285 14 vs vs IN cord-006870-f5w6fw6q 285 15 poor poor JJ cord-006870-f5w6fw6q 285 16 , , , cord-006870-f5w6fw6q 285 17 p=0.1 p=0.1 NNP cord-006870-f5w6fw6q 285 18 ) ) -RRB- cord-006870-f5w6fw6q 285 19 . . . cord-006870-f5w6fw6q 286 1 In in IN cord-006870-f5w6fw6q 286 2 comatose comatose JJ cord-006870-f5w6fw6q 286 3 patients patient NNS cord-006870-f5w6fw6q 286 4 following follow VBG cord-006870-f5w6fw6q 286 5 cardiac cardiac JJ cord-006870-f5w6fw6q 286 6 arrest arrest NN cord-006870-f5w6fw6q 286 7 higher high JJR cord-006870-f5w6fw6q 286 8 fMRI fMRI NNP cord-006870-f5w6fw6q 286 9 measured measure VBN cord-006870-f5w6fw6q 286 10 resting rest VBG cord-006870-f5w6fw6q 286 11 state state NN cord-006870-f5w6fw6q 286 12 connectivity connectivity NN cord-006870-f5w6fw6q 286 13 correlated correlate VBN cord-006870-f5w6fw6q 286 14 with with IN cord-006870-f5w6fw6q 286 15 consciousness consciousness NN cord-006870-f5w6fw6q 286 16 recovery recovery NN cord-006870-f5w6fw6q 286 17 . . . cord-006870-f5w6fw6q 287 1 Functional functional JJ cord-006870-f5w6fw6q 287 2 connectivity connectivity NN cord-006870-f5w6fw6q 287 3 may may MD cord-006870-f5w6fw6q 287 4 be be VB cord-006870-f5w6fw6q 287 5 developed develop VBN cord-006870-f5w6fw6q 287 6 as as IN cord-006870-f5w6fw6q 287 7 a a DT cord-006870-f5w6fw6q 287 8 prognostic prognostic JJ cord-006870-f5w6fw6q 287 9 biomarker biomarker NN cord-006870-f5w6fw6q 287 10 . . . cord-006870-f5w6fw6q 288 1 Sedative sedative JJ cord-006870-f5w6fw6q 288 2 and and CC cord-006870-f5w6fw6q 288 3 analgesic analgesic JJ cord-006870-f5w6fw6q 288 4 infusions infusion NNS cord-006870-f5w6fw6q 288 5 and and CC cord-006870-f5w6fw6q 288 6 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 288 7 blockade blockade NN cord-006870-f5w6fw6q 288 8 agents agent NNS cord-006870-f5w6fw6q 288 9 ( ( -LRB- cord-006870-f5w6fw6q 288 10 NMBA NMBA NNP cord-006870-f5w6fw6q 288 11 ) ) -RRB- cord-006870-f5w6fw6q 288 12 are be VBP cord-006870-f5w6fw6q 288 13 commonly commonly RB cord-006870-f5w6fw6q 288 14 used use VBN cord-006870-f5w6fw6q 288 15 for for IN cord-006870-f5w6fw6q 288 16 comfort comfort NN cord-006870-f5w6fw6q 288 17 , , , cord-006870-f5w6fw6q 288 18 suppression suppression NN cord-006870-f5w6fw6q 288 19 of of IN cord-006870-f5w6fw6q 288 20 shivering shivering NN cord-006870-f5w6fw6q 288 21 , , , cord-006870-f5w6fw6q 288 22 and and CC cord-006870-f5w6fw6q 288 23 reduction reduction NN cord-006870-f5w6fw6q 288 24 of of IN cord-006870-f5w6fw6q 288 25 metabolic metabolic JJ cord-006870-f5w6fw6q 288 26 activity activity NN cord-006870-f5w6fw6q 288 27 during during IN cord-006870-f5w6fw6q 288 28 targeted target VBN cord-006870-f5w6fw6q 288 29 temperature temperature NN cord-006870-f5w6fw6q 288 30 management management NN cord-006870-f5w6fw6q 288 31 ( ( -LRB- cord-006870-f5w6fw6q 288 32 TTM TTM NNP cord-006870-f5w6fw6q 288 33 ) ) -RRB- cord-006870-f5w6fw6q 288 34 after after IN cord-006870-f5w6fw6q 288 35 cardiac cardiac JJ cord-006870-f5w6fw6q 288 36 arrest arrest NN cord-006870-f5w6fw6q 288 37 . . . cord-006870-f5w6fw6q 289 1 The the DT cord-006870-f5w6fw6q 289 2 optimal optimal JJ cord-006870-f5w6fw6q 289 3 sedation sedation NN cord-006870-f5w6fw6q 289 4 and and CC cord-006870-f5w6fw6q 289 5 analgesia analgesia NN cord-006870-f5w6fw6q 289 6 regimens regimen NNS cord-006870-f5w6fw6q 289 7 are be VBP cord-006870-f5w6fw6q 289 8 unknown unknown JJ cord-006870-f5w6fw6q 289 9 . . . cord-006870-f5w6fw6q 290 1 We -PRON- PRP cord-006870-f5w6fw6q 290 2 sought seek VBD cord-006870-f5w6fw6q 290 3 to to TO cord-006870-f5w6fw6q 290 4 describe describe VB cord-006870-f5w6fw6q 290 5 variability variability NN cord-006870-f5w6fw6q 290 6 in in IN cord-006870-f5w6fw6q 290 7 sedation sedation NN cord-006870-f5w6fw6q 290 8 and and CC cord-006870-f5w6fw6q 290 9 shivering shiver VBG cord-006870-f5w6fw6q 290 10 management management NN cord-006870-f5w6fw6q 290 11 practices practice NNS cord-006870-f5w6fw6q 290 12 at at IN cord-006870-f5w6fw6q 290 13 US US NNP cord-006870-f5w6fw6q 290 14 and and CC cord-006870-f5w6fw6q 290 15 European european JJ cord-006870-f5w6fw6q 290 16 cardiac cardiac JJ cord-006870-f5w6fw6q 290 17 arrest arrest NN cord-006870-f5w6fw6q 290 18 receiving receive VBG cord-006870-f5w6fw6q 290 19 centers center NNS cord-006870-f5w6fw6q 290 20 . . . cord-006870-f5w6fw6q 291 1 International International NNP cord-006870-f5w6fw6q 291 2 Cardiac Cardiac NNP cord-006870-f5w6fw6q 291 3 Arrest Arrest NNP cord-006870-f5w6fw6q 291 4 Registry Registry NNP cord-006870-f5w6fw6q 291 5 ( ( -LRB- cord-006870-f5w6fw6q 291 6 INTCAR INTCAR NNP cord-006870-f5w6fw6q 291 7 ) ) -RRB- cord-006870-f5w6fw6q 291 8 centers center NNS cord-006870-f5w6fw6q 291 9 were be VBD cord-006870-f5w6fw6q 291 10 surveyed survey VBN cord-006870-f5w6fw6q 291 11 regarding regard VBG cord-006870-f5w6fw6q 291 12 sedation sedation NN cord-006870-f5w6fw6q 291 13 protocols protocol NNS cord-006870-f5w6fw6q 291 14 for for IN cord-006870-f5w6fw6q 291 15 TTM TTM NNP cord-006870-f5w6fw6q 291 16 after after IN cord-006870-f5w6fw6q 291 17 cardiac cardiac JJ cord-006870-f5w6fw6q 291 18 arrest arrest NN cord-006870-f5w6fw6q 291 19 . . . cord-006870-f5w6fw6q 292 1 The the DT cord-006870-f5w6fw6q 292 2 survey survey NN cord-006870-f5w6fw6q 292 3 was be VBD cord-006870-f5w6fw6q 292 4 administered administer VBN cord-006870-f5w6fw6q 292 5 via via IN cord-006870-f5w6fw6q 292 6 REDCap REDCap NNS cord-006870-f5w6fw6q 292 7 with with IN cord-006870-f5w6fw6q 292 8 a a DT cord-006870-f5w6fw6q 292 9 response response NN cord-006870-f5w6fw6q 292 10 rate rate NN cord-006870-f5w6fw6q 292 11 of of IN cord-006870-f5w6fw6q 292 12 48 48 CD cord-006870-f5w6fw6q 292 13 % % NN cord-006870-f5w6fw6q 292 14 . . . cord-006870-f5w6fw6q 293 1 Ten Ten NNP cord-006870-f5w6fw6q 293 2 United United NNP cord-006870-f5w6fw6q 293 3 States States NNP cord-006870-f5w6fw6q 293 4 and and CC cord-006870-f5w6fw6q 293 5 28 28 CD cord-006870-f5w6fw6q 293 6 European european JJ cord-006870-f5w6fw6q 293 7 centers center NNS cord-006870-f5w6fw6q 293 8 completed complete VBD cord-006870-f5w6fw6q 293 9 the the DT cord-006870-f5w6fw6q 293 10 survey survey NN cord-006870-f5w6fw6q 293 11 . . . cord-006870-f5w6fw6q 294 1 Shivering shiver VBG cord-006870-f5w6fw6q 294 2 is be VBZ cord-006870-f5w6fw6q 294 3 measured measure VBN cord-006870-f5w6fw6q 294 4 at at IN cord-006870-f5w6fw6q 294 5 35 35 CD cord-006870-f5w6fw6q 294 6 ( ( -LRB- cord-006870-f5w6fw6q 294 7 92 92 CD cord-006870-f5w6fw6q 294 8 % % NN cord-006870-f5w6fw6q 294 9 ) ) -RRB- cord-006870-f5w6fw6q 294 10 of of IN cord-006870-f5w6fw6q 294 11 centers center NNS cord-006870-f5w6fw6q 294 12 and and CC cord-006870-f5w6fw6q 294 13 recorded record VBD cord-006870-f5w6fw6q 294 14 at at IN cord-006870-f5w6fw6q 294 15 14 14 CD cord-006870-f5w6fw6q 294 16 ( ( -LRB- cord-006870-f5w6fw6q 294 17 37 37 CD cord-006870-f5w6fw6q 294 18 % % NN cord-006870-f5w6fw6q 294 19 ) ) -RRB- cord-006870-f5w6fw6q 294 20 centers center NNS cord-006870-f5w6fw6q 294 21 . . . cord-006870-f5w6fw6q 295 1 Ten ten CD cord-006870-f5w6fw6q 295 2 centers center NNS cord-006870-f5w6fw6q 295 3 use use VBP cord-006870-f5w6fw6q 295 4 NMB NMB NNP cord-006870-f5w6fw6q 295 5 to to TO cord-006870-f5w6fw6q 295 6 control control VB cord-006870-f5w6fw6q 295 7 shivering shivering NN cord-006870-f5w6fw6q 295 8 prophylactically prophylactically RB cord-006870-f5w6fw6q 295 9 , , , cord-006870-f5w6fw6q 295 10 12 12 CD cord-006870-f5w6fw6q 295 11 centers center NNS cord-006870-f5w6fw6q 295 12 use use VBP cord-006870-f5w6fw6q 295 13 NMB NMB NNP cord-006870-f5w6fw6q 295 14 only only RB cord-006870-f5w6fw6q 295 15 if if IN cord-006870-f5w6fw6q 295 16 shivering shivering NN cord-006870-f5w6fw6q 295 17 occurs occur VBZ cord-006870-f5w6fw6q 295 18 , , , cord-006870-f5w6fw6q 295 19 and and CC cord-006870-f5w6fw6q 295 20 16 16 CD cord-006870-f5w6fw6q 295 21 centers center NNS cord-006870-f5w6fw6q 295 22 increase increase VBP cord-006870-f5w6fw6q 295 23 opioids opioid NNS cord-006870-f5w6fw6q 295 24 or or CC cord-006870-f5w6fw6q 295 25 sedatives sedative NNS cord-006870-f5w6fw6q 295 26 when when WRB cord-006870-f5w6fw6q 295 27 shivering shivering NN cord-006870-f5w6fw6q 295 28 occurs occur VBZ cord-006870-f5w6fw6q 295 29 , , , cord-006870-f5w6fw6q 295 30 but but CC cord-006870-f5w6fw6q 295 31 do do VBP cord-006870-f5w6fw6q 295 32 not not RB cord-006870-f5w6fw6q 295 33 use use VB cord-006870-f5w6fw6q 295 34 NMB NMB NNP cord-006870-f5w6fw6q 295 35 . . . cord-006870-f5w6fw6q 296 1 The the DT cord-006870-f5w6fw6q 296 2 most most RBS cord-006870-f5w6fw6q 296 3 common common JJ cord-006870-f5w6fw6q 296 4 sedative sedative NN cord-006870-f5w6fw6q 296 5 was be VBD cord-006870-f5w6fw6q 296 6 propofol propofol NN cord-006870-f5w6fw6q 296 7 ( ( -LRB- cord-006870-f5w6fw6q 296 8 31/38 31/38 CD cord-006870-f5w6fw6q 296 9 centers center NNS cord-006870-f5w6fw6q 296 10 ) ) -RRB- cord-006870-f5w6fw6q 296 11 , , , cord-006870-f5w6fw6q 296 12 followed follow VBN cord-006870-f5w6fw6q 296 13 by by IN cord-006870-f5w6fw6q 296 14 midazolam midazolam NNP cord-006870-f5w6fw6q 296 15 ( ( -LRB- cord-006870-f5w6fw6q 296 16 24/36 24/36 CD cord-006870-f5w6fw6q 296 17 ) ) -RRB- cord-006870-f5w6fw6q 296 18 and and CC cord-006870-f5w6fw6q 296 19 the the DT cord-006870-f5w6fw6q 296 20 most most RBS cord-006870-f5w6fw6q 296 21 common common JJ cord-006870-f5w6fw6q 296 22 analgesic analgesic NN cord-006870-f5w6fw6q 296 23 was be VBD cord-006870-f5w6fw6q 296 24 fentanyl fentanyl NN cord-006870-f5w6fw6q 296 25 ( ( -LRB- cord-006870-f5w6fw6q 296 26 25/38 25/38 CD cord-006870-f5w6fw6q 296 27 ) ) -RRB- cord-006870-f5w6fw6q 296 28 followed follow VBN cord-006870-f5w6fw6q 296 29 by by IN cord-006870-f5w6fw6q 296 30 remifentanyl remifentanyl NNP cord-006870-f5w6fw6q 296 31 ( ( -LRB- cord-006870-f5w6fw6q 296 32 17/25 17/25 CD cord-006870-f5w6fw6q 296 33 ) ) -RRB- cord-006870-f5w6fw6q 296 34 . . . cord-006870-f5w6fw6q 296 35 0 0 NFP cord-006870-f5w6fw6q 296 36 , , , cord-006870-f5w6fw6q 296 37 18 18 CD cord-006870-f5w6fw6q 296 38 , , , cord-006870-f5w6fw6q 296 39 and and CC cord-006870-f5w6fw6q 296 40 21 21 CD cord-006870-f5w6fw6q 296 41 centers center NNS cord-006870-f5w6fw6q 296 42 report report NN cord-006870-f5w6fw6q 296 43 having have VBG cord-006870-f5w6fw6q 296 44 a a DT cord-006870-f5w6fw6q 296 45 sedation sedation NN cord-006870-f5w6fw6q 296 46 target target NN cord-006870-f5w6fw6q 296 47 of of IN cord-006870-f5w6fw6q 296 48 light light NN cord-006870-f5w6fw6q 296 49 , , , cord-006870-f5w6fw6q 296 50 moderate moderate JJ cord-006870-f5w6fw6q 296 51 , , , cord-006870-f5w6fw6q 296 52 or or CC cord-006870-f5w6fw6q 296 53 deep deep JJ cord-006870-f5w6fw6q 296 54 respectively respectively RB cord-006870-f5w6fw6q 296 55 . . . cord-006870-f5w6fw6q 297 1 A a DT cord-006870-f5w6fw6q 297 2 sedation sedation NN cord-006870-f5w6fw6q 297 3 scale scale NN cord-006870-f5w6fw6q 297 4 is be VBZ cord-006870-f5w6fw6q 297 5 used use VBN cord-006870-f5w6fw6q 297 6 at at IN cord-006870-f5w6fw6q 297 7 25 25 CD cord-006870-f5w6fw6q 297 8 ( ( -LRB- cord-006870-f5w6fw6q 297 9 66 66 CD cord-006870-f5w6fw6q 297 10 % % NN cord-006870-f5w6fw6q 297 11 ) ) -RRB- cord-006870-f5w6fw6q 297 12 centers center NNS cord-006870-f5w6fw6q 297 13 , , , cord-006870-f5w6fw6q 297 14 targeted target VBN cord-006870-f5w6fw6q 297 15 to to IN cord-006870-f5w6fw6q 297 16 patient patient JJ cord-006870-f5w6fw6q 297 17 comfort comfort NN cord-006870-f5w6fw6q 297 18 at at IN cord-006870-f5w6fw6q 297 19 8 8 CD cord-006870-f5w6fw6q 297 20 ( ( -LRB- cord-006870-f5w6fw6q 297 21 21 21 CD cord-006870-f5w6fw6q 297 22 % % NN cord-006870-f5w6fw6q 297 23 ) ) -RRB- cord-006870-f5w6fw6q 297 24 centers center NNS cord-006870-f5w6fw6q 297 25 . . . cord-006870-f5w6fw6q 298 1 Daily daily JJ cord-006870-f5w6fw6q 298 2 sedation sedation NN cord-006870-f5w6fw6q 298 3 lightening lightening NN cord-006870-f5w6fw6q 298 4 is be VBZ cord-006870-f5w6fw6q 298 5 protocolized protocolize VBN cord-006870-f5w6fw6q 298 6 when when WRB cord-006870-f5w6fw6q 298 7 rewarming rewarming NN cord-006870-f5w6fw6q 298 8 starts start VBZ cord-006870-f5w6fw6q 298 9 at at IN cord-006870-f5w6fw6q 298 10 6 6 CD cord-006870-f5w6fw6q 298 11 ( ( -LRB- cord-006870-f5w6fw6q 298 12 16 16 CD cord-006870-f5w6fw6q 298 13 % % NN cord-006870-f5w6fw6q 298 14 ) ) -RRB- cord-006870-f5w6fw6q 298 15 centers center NNS cord-006870-f5w6fw6q 298 16 , , , cord-006870-f5w6fw6q 298 17 when when WRB cord-006870-f5w6fw6q 298 18 normothermia normothermia NN cord-006870-f5w6fw6q 298 19 is be VBZ cord-006870-f5w6fw6q 298 20 reached reach VBN cord-006870-f5w6fw6q 298 21 at at IN cord-006870-f5w6fw6q 298 22 28 28 CD cord-006870-f5w6fw6q 298 23 ( ( -LRB- cord-006870-f5w6fw6q 298 24 72 72 CD cord-006870-f5w6fw6q 298 25 % % NN cord-006870-f5w6fw6q 298 26 ) ) -RRB- cord-006870-f5w6fw6q 298 27 and and CC cord-006870-f5w6fw6q 298 28 not not RB cord-006870-f5w6fw6q 298 29 specified specify VBN cord-006870-f5w6fw6q 298 30 in in IN cord-006870-f5w6fw6q 298 31 the the DT cord-006870-f5w6fw6q 298 32 remainder remainder NN cord-006870-f5w6fw6q 298 33 of of IN cord-006870-f5w6fw6q 298 34 groups group NNS cord-006870-f5w6fw6q 298 35 . . . cord-006870-f5w6fw6q 299 1 Of of IN cord-006870-f5w6fw6q 299 2 patients patient NNS cord-006870-f5w6fw6q 299 3 who who WP cord-006870-f5w6fw6q 299 4 awaken awaken VBP cord-006870-f5w6fw6q 299 5 , , , cord-006870-f5w6fw6q 299 6 centers center NNS cord-006870-f5w6fw6q 299 7 report report VBP cord-006870-f5w6fw6q 299 8 that that IN cord-006870-f5w6fw6q 299 9 they -PRON- PRP cord-006870-f5w6fw6q 299 10 expect expect VBP cord-006870-f5w6fw6q 299 11 this this DT cord-006870-f5w6fw6q 299 12 to to TO cord-006870-f5w6fw6q 299 13 occur occur VB cord-006870-f5w6fw6q 299 14 at at IN cord-006870-f5w6fw6q 299 15 24 24 CD cord-006870-f5w6fw6q 299 16 ( ( -LRB- cord-006870-f5w6fw6q 299 17 17 17 CD cord-006870-f5w6fw6q 299 18 centers center NNS cord-006870-f5w6fw6q 299 19 ) ) -RRB- cord-006870-f5w6fw6q 299 20 , , , cord-006870-f5w6fw6q 299 21 48 48 CD cord-006870-f5w6fw6q 299 22 ( ( -LRB- cord-006870-f5w6fw6q 299 23 12 12 CD cord-006870-f5w6fw6q 299 24 centers center NNS cord-006870-f5w6fw6q 299 25 ) ) -RRB- cord-006870-f5w6fw6q 299 26 and and CC cord-006870-f5w6fw6q 299 27 72 72 CD cord-006870-f5w6fw6q 299 28 ( ( -LRB- cord-006870-f5w6fw6q 299 29 6 6 CD cord-006870-f5w6fw6q 299 30 centers center NNS cord-006870-f5w6fw6q 299 31 ) ) -RRB- cord-006870-f5w6fw6q 299 32 hours hour NNS cord-006870-f5w6fw6q 299 33 respectively respectively RB cord-006870-f5w6fw6q 299 34 . . . cord-006870-f5w6fw6q 300 1 Among among IN cord-006870-f5w6fw6q 300 2 cardiac cardiac JJ cord-006870-f5w6fw6q 300 3 arrest arrest NN cord-006870-f5w6fw6q 300 4 receiving receive VBG cord-006870-f5w6fw6q 300 5 centers center NNS cord-006870-f5w6fw6q 300 6 internationally internationally RB cord-006870-f5w6fw6q 300 7 , , , cord-006870-f5w6fw6q 300 8 there there EX cord-006870-f5w6fw6q 300 9 is be VBZ cord-006870-f5w6fw6q 300 10 significant significant JJ cord-006870-f5w6fw6q 300 11 variability variability NN cord-006870-f5w6fw6q 300 12 in in IN cord-006870-f5w6fw6q 300 13 TTM TTM NNP cord-006870-f5w6fw6q 300 14 sedation sedation NN cord-006870-f5w6fw6q 300 15 and and CC cord-006870-f5w6fw6q 300 16 shivering shiver VBG cord-006870-f5w6fw6q 300 17 management management NN cord-006870-f5w6fw6q 300 18 strategy strategy NN cord-006870-f5w6fw6q 300 19 . . . cord-006870-f5w6fw6q 301 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 301 2 hospital hospital NN cord-006870-f5w6fw6q 301 3 policy policy NN cord-006870-f5w6fw6q 301 4 allows allow VBZ cord-006870-f5w6fw6q 301 5 an an DT cord-006870-f5w6fw6q 301 6 optional optional JJ cord-006870-f5w6fw6q 301 7 SBD SBD NNP cord-006870-f5w6fw6q 301 8 ( ( -LRB- cord-006870-f5w6fw6q 301 9 with with IN cord-006870-f5w6fw6q 301 10 an an DT cord-006870-f5w6fw6q 301 11 apnea apnea NN cord-006870-f5w6fw6q 301 12 and and CC cord-006870-f5w6fw6q 301 13 a a DT cord-006870-f5w6fw6q 301 14 cerebral cerebral JJ cord-006870-f5w6fw6q 301 15 blood blood NN cord-006870-f5w6fw6q 301 16 flow flow NN cord-006870-f5w6fw6q 301 17 test test NN cord-006870-f5w6fw6q 301 18 ) ) -RRB- cord-006870-f5w6fw6q 301 19 or or CC cord-006870-f5w6fw6q 301 20 a a DT cord-006870-f5w6fw6q 301 21 DBD DBD NNP cord-006870-f5w6fw6q 301 22 ( ( -LRB- cord-006870-f5w6fw6q 301 23 with with IN cord-006870-f5w6fw6q 301 24 an an DT cord-006870-f5w6fw6q 301 25 apnea apnea NN cord-006870-f5w6fw6q 301 26 test test NN cord-006870-f5w6fw6q 301 27 ) ) -RRB- cord-006870-f5w6fw6q 301 28 . . . cord-006870-f5w6fw6q 302 1 We -PRON- PRP cord-006870-f5w6fw6q 302 2 have have VBP cord-006870-f5w6fw6q 302 3 evaluated evaluate VBN cord-006870-f5w6fw6q 302 4 the the DT cord-006870-f5w6fw6q 302 5 adoption adoption NN cord-006870-f5w6fw6q 302 6 of of IN cord-006870-f5w6fw6q 302 7 and and CC cord-006870-f5w6fw6q 302 8 reason reason NN cord-006870-f5w6fw6q 302 9 for for IN cord-006870-f5w6fw6q 302 10 performing perform VBG cord-006870-f5w6fw6q 302 11 a a DT cord-006870-f5w6fw6q 302 12 single single JJ cord-006870-f5w6fw6q 302 13 brain brain NN cord-006870-f5w6fw6q 302 14 death death NN cord-006870-f5w6fw6q 302 15 exam exam NN cord-006870-f5w6fw6q 302 16 ( ( -LRB- cord-006870-f5w6fw6q 302 17 SBD SBD NNP cord-006870-f5w6fw6q 302 18 ) ) -RRB- cord-006870-f5w6fw6q 302 19 vs vs IN cord-006870-f5w6fw6q 302 20 two two CD cord-006870-f5w6fw6q 302 21 ( ( -LRB- cord-006870-f5w6fw6q 302 22 dual dual JJ cord-006870-f5w6fw6q 302 23 ) ) -RRB- cord-006870-f5w6fw6q 302 24 brain brain NN cord-006870-f5w6fw6q 302 25 death death NN cord-006870-f5w6fw6q 302 26 exams exam NNS cord-006870-f5w6fw6q 302 27 ( ( -LRB- cord-006870-f5w6fw6q 302 28 DBD DBD NNP cord-006870-f5w6fw6q 302 29 ) ) -RRB- cord-006870-f5w6fw6q 302 30 and and CC cord-006870-f5w6fw6q 302 31 their -PRON- PRP$ cord-006870-f5w6fw6q 302 32 impact impact NN cord-006870-f5w6fw6q 302 33 on on IN cord-006870-f5w6fw6q 302 34 organ organ NN cord-006870-f5w6fw6q 302 35 function function NN cord-006870-f5w6fw6q 302 36 and and CC cord-006870-f5w6fw6q 302 37 consent consent NN cord-006870-f5w6fw6q 302 38 for for IN cord-006870-f5w6fw6q 302 39 organ organ NN cord-006870-f5w6fw6q 302 40 donation donation NN cord-006870-f5w6fw6q 302 41 . . . cord-006870-f5w6fw6q 303 1 We -PRON- PRP cord-006870-f5w6fw6q 303 2 evaluated evaluate VBD cord-006870-f5w6fw6q 303 3 our -PRON- PRP$ cord-006870-f5w6fw6q 303 4 hospital hospital NN cord-006870-f5w6fw6q 303 5 's 's POS cord-006870-f5w6fw6q 303 6 BD BD NNP cord-006870-f5w6fw6q 303 7 registry registry NN cord-006870-f5w6fw6q 303 8 between between IN cord-006870-f5w6fw6q 303 9 January January NNP cord-006870-f5w6fw6q 303 10 2006 2006 CD cord-006870-f5w6fw6q 303 11 and and CC cord-006870-f5w6fw6q 303 12 June June NNP cord-006870-f5w6fw6q 303 13 2017 2017 CD cord-006870-f5w6fw6q 303 14 regarding regard VBG cord-006870-f5w6fw6q 303 15 SBD SBD NNP cord-006870-f5w6fw6q 303 16 or or CC cord-006870-f5w6fw6q 303 17 DBD DBD NNP cord-006870-f5w6fw6q 303 18 . . . cord-006870-f5w6fw6q 304 1 We -PRON- PRP cord-006870-f5w6fw6q 304 2 also also RB cord-006870-f5w6fw6q 304 3 cross cross VBP cord-006870-f5w6fw6q 304 4 - - JJ cord-006870-f5w6fw6q 304 5 matched match VBN cord-006870-f5w6fw6q 304 6 our -PRON- PRP$ cord-006870-f5w6fw6q 304 7 electronic electronic JJ cord-006870-f5w6fw6q 304 8 medical medical JJ cord-006870-f5w6fw6q 304 9 records record NNS cord-006870-f5w6fw6q 304 10 with with IN cord-006870-f5w6fw6q 304 11 the the DT cord-006870-f5w6fw6q 304 12 records record NNS cord-006870-f5w6fw6q 304 13 of of IN cord-006870-f5w6fw6q 304 14 the the DT cord-006870-f5w6fw6q 304 15 local local JJ cord-006870-f5w6fw6q 304 16 organ organ NN cord-006870-f5w6fw6q 304 17 procurement procurement NN cord-006870-f5w6fw6q 304 18 organization organization NN cord-006870-f5w6fw6q 304 19 . . . cord-006870-f5w6fw6q 305 1 Of of IN cord-006870-f5w6fw6q 305 2 251 251 CD cord-006870-f5w6fw6q 305 3 BD BD NNP cord-006870-f5w6fw6q 305 4 declarations declaration NNS cord-006870-f5w6fw6q 305 5 , , , cord-006870-f5w6fw6q 305 6 115 115 CD cord-006870-f5w6fw6q 305 7 ( ( -LRB- cord-006870-f5w6fw6q 305 8 46 46 CD cord-006870-f5w6fw6q 305 9 % % NN cord-006870-f5w6fw6q 305 10 ) ) -RRB- cord-006870-f5w6fw6q 305 11 were be VBD cord-006870-f5w6fw6q 305 12 SBD SBD NNP cord-006870-f5w6fw6q 305 13 and and CC cord-006870-f5w6fw6q 305 14 136 136 CD cord-006870-f5w6fw6q 305 15 ( ( -LRB- cord-006870-f5w6fw6q 305 16 54 54 CD cord-006870-f5w6fw6q 305 17 % % NN cord-006870-f5w6fw6q 305 18 ) ) -RRB- cord-006870-f5w6fw6q 305 19 DBD DBD NNP cord-006870-f5w6fw6q 305 20 . . . cord-006870-f5w6fw6q 306 1 During during IN cord-006870-f5w6fw6q 306 2 the the DT cord-006870-f5w6fw6q 306 3 1st 1st JJ cord-006870-f5w6fw6q 306 4 five five CD cord-006870-f5w6fw6q 306 5 years year NNS cord-006870-f5w6fw6q 306 6 , , , cord-006870-f5w6fw6q 306 7 43 43 CD cord-006870-f5w6fw6q 306 8 % % NN cord-006870-f5w6fw6q 306 9 of of IN cord-006870-f5w6fw6q 306 10 all all DT cord-006870-f5w6fw6q 306 11 BD BD NNP cord-006870-f5w6fw6q 306 12 exams exam NNS cord-006870-f5w6fw6q 306 13 were be VBD cord-006870-f5w6fw6q 306 14 SBD SBD NNP cord-006870-f5w6fw6q 306 15 and and CC cord-006870-f5w6fw6q 306 16 during during IN cord-006870-f5w6fw6q 306 17 the the DT cord-006870-f5w6fw6q 306 18 second second JJ cord-006870-f5w6fw6q 306 19 57 57 CD cord-006870-f5w6fw6q 306 20 % % NN cord-006870-f5w6fw6q 306 21 . . . cord-006870-f5w6fw6q 307 1 Patients patient NNS cord-006870-f5w6fw6q 307 2 with with IN cord-006870-f5w6fw6q 307 3 SBD SBD NNP cord-006870-f5w6fw6q 307 4 were be VBD cord-006870-f5w6fw6q 307 5 older old JJR cord-006870-f5w6fw6q 307 6 ( ( -LRB- cord-006870-f5w6fw6q 307 7 50.6±16.5 50.6±16.5 CD cord-006870-f5w6fw6q 307 8 for for IN cord-006870-f5w6fw6q 307 9 SBD SBD NNP cord-006870-f5w6fw6q 307 10 vs vs IN cord-006870-f5w6fw6q 307 11 46.5±17.1 46.5±17.1 CD cord-006870-f5w6fw6q 307 12 years year NNS cord-006870-f5w6fw6q 307 13 for for IN cord-006870-f5w6fw6q 307 14 DBD DBD NNP cord-006870-f5w6fw6q 307 15 , , , cord-006870-f5w6fw6q 307 16 p= p= NNP cord-006870-f5w6fw6q 307 17 0.057 0.057 CD cord-006870-f5w6fw6q 307 18 ) ) -RRB- cord-006870-f5w6fw6q 307 19 , , , cord-006870-f5w6fw6q 307 20 had have VBD cord-006870-f5w6fw6q 307 21 a a DT cord-006870-f5w6fw6q 307 22 primary primary JJ cord-006870-f5w6fw6q 307 23 neurologic neurologic JJ cord-006870-f5w6fw6q 307 24 diagnosis diagnosis NN cord-006870-f5w6fw6q 307 25 ( ( -LRB- cord-006870-f5w6fw6q 307 26 96 96 CD cord-006870-f5w6fw6q 307 27 % % NN cord-006870-f5w6fw6q 307 28 vs vs IN cord-006870-f5w6fw6q 307 29 47 47 CD cord-006870-f5w6fw6q 307 30 % % NN cord-006870-f5w6fw6q 307 31 , , , cord-006870-f5w6fw6q 307 32 p p NN cord-006870-f5w6fw6q 307 33 < < XX cord-006870-f5w6fw6q 307 34 0.001 0.001 CD cord-006870-f5w6fw6q 307 35 ) ) -RRB- cord-006870-f5w6fw6q 307 36 and and CC cord-006870-f5w6fw6q 307 37 were be VBD cord-006870-f5w6fw6q 307 38 admitted admit VBN cord-006870-f5w6fw6q 307 39 to to IN cord-006870-f5w6fw6q 307 40 the the DT cord-006870-f5w6fw6q 307 41 Neuro Neuro NNP cord-006870-f5w6fw6q 307 42 - - HYPH cord-006870-f5w6fw6q 307 43 ICU ICU NNP cord-006870-f5w6fw6q 307 44 ( ( -LRB- cord-006870-f5w6fw6q 307 45 74 74 CD cord-006870-f5w6fw6q 307 46 % % NN cord-006870-f5w6fw6q 307 47 vs vs IN cord-006870-f5w6fw6q 307 48 27 27 CD cord-006870-f5w6fw6q 307 49 % % NN cord-006870-f5w6fw6q 307 50 , , , cord-006870-f5w6fw6q 307 51 p p NN cord-006870-f5w6fw6q 307 52 < < XX cord-006870-f5w6fw6q 307 53 0.001 0.001 CD cord-006870-f5w6fw6q 307 54 ) ) -RRB- cord-006870-f5w6fw6q 307 55 . . . cord-006870-f5w6fw6q 308 1 During during IN cord-006870-f5w6fw6q 308 2 the the DT cord-006870-f5w6fw6q 308 3 2nd 2nd JJ cord-006870-f5w6fw6q 308 4 exam exam NN cord-006870-f5w6fw6q 308 5 , , , cord-006870-f5w6fw6q 308 6 76.7 76.7 CD cord-006870-f5w6fw6q 308 7 % % NN cord-006870-f5w6fw6q 308 8 patients patient NNS cord-006870-f5w6fw6q 308 9 were be VBD cord-006870-f5w6fw6q 308 10 on on IN cord-006870-f5w6fw6q 308 11 equal equal JJ cord-006870-f5w6fw6q 308 12 or or CC cord-006870-f5w6fw6q 308 13 higher high JJR cord-006870-f5w6fw6q 308 14 dose dose NN cord-006870-f5w6fw6q 308 15 of of IN cord-006870-f5w6fw6q 308 16 pressors pressor NNS cord-006870-f5w6fw6q 308 17 . . . cord-006870-f5w6fw6q 309 1 SBD SBD NNP cord-006870-f5w6fw6q 309 2 patients patient NNS cord-006870-f5w6fw6q 309 3 had have VBD cord-006870-f5w6fw6q 309 4 lower low JJR cord-006870-f5w6fw6q 309 5 K+ K+ NNP cord-006870-f5w6fw6q 309 6 , , , cord-006870-f5w6fw6q 309 7 BUN bun NN cord-006870-f5w6fw6q 309 8 , , , cord-006870-f5w6fw6q 309 9 creatinine creatinine NN cord-006870-f5w6fw6q 309 10 and and CC cord-006870-f5w6fw6q 309 11 heart heart NN cord-006870-f5w6fw6q 309 12 rate rate NN cord-006870-f5w6fw6q 309 13 , , , cord-006870-f5w6fw6q 309 14 but but CC cord-006870-f5w6fw6q 309 15 higher high JJR cord-006870-f5w6fw6q 309 16 peak peak NN cord-006870-f5w6fw6q 309 17 Na+ na+ NN cord-006870-f5w6fw6q 309 18 and and CC cord-006870-f5w6fw6q 309 19 apnea apnea NN cord-006870-f5w6fw6q 309 20 PaO2 PaO2 NNS cord-006870-f5w6fw6q 309 21 ( ( -LRB- cord-006870-f5w6fw6q 309 22 for for IN cord-006870-f5w6fw6q 309 23 all all DT cord-006870-f5w6fw6q 309 24 p<0.05 p<0.05 CD cord-006870-f5w6fw6q 309 25 ) ) -RRB- cord-006870-f5w6fw6q 309 26 , , , cord-006870-f5w6fw6q 309 27 although although IN cord-006870-f5w6fw6q 309 28 apnea apnea NN cord-006870-f5w6fw6q 309 29 pH pH NNP cord-006870-f5w6fw6q 309 30 and and CC cord-006870-f5w6fw6q 309 31 PaCO2 PaCO2 NNP cord-006870-f5w6fw6q 309 32 were be VBD cord-006870-f5w6fw6q 309 33 similar similar JJ cord-006870-f5w6fw6q 309 34 . . . cord-006870-f5w6fw6q 310 1 The the DT cord-006870-f5w6fw6q 310 2 time time NN cord-006870-f5w6fw6q 310 3 between between IN cord-006870-f5w6fw6q 310 4 injury injury NN cord-006870-f5w6fw6q 310 5 to to IN cord-006870-f5w6fw6q 310 6 BD BD NNP cord-006870-f5w6fw6q 310 7 pronouncement pronouncement NN cord-006870-f5w6fw6q 310 8 was be VBD cord-006870-f5w6fw6q 310 9 shorter short JJR cord-006870-f5w6fw6q 310 10 in in IN cord-006870-f5w6fw6q 310 11 SBD SBD NNP cord-006870-f5w6fw6q 310 12 by by IN cord-006870-f5w6fw6q 310 13 29.4 29.4 CD cord-006870-f5w6fw6q 310 14 hours hour NNS cord-006870-f5w6fw6q 310 15 . . . cord-006870-f5w6fw6q 311 1 There there EX cord-006870-f5w6fw6q 311 2 was be VBD cord-006870-f5w6fw6q 311 3 no no DT cord-006870-f5w6fw6q 311 4 difference difference NN cord-006870-f5w6fw6q 311 5 in in IN cord-006870-f5w6fw6q 311 6 consent consent NN cord-006870-f5w6fw6q 311 7 rate rate NN cord-006870-f5w6fw6q 311 8 between between IN cord-006870-f5w6fw6q 311 9 SBD SBD NNP cord-006870-f5w6fw6q 311 10 and and CC cord-006870-f5w6fw6q 311 11 DBD DBD NNP cord-006870-f5w6fw6q 311 12 ( ( -LRB- cord-006870-f5w6fw6q 311 13 74 74 CD cord-006870-f5w6fw6q 311 14 % % NN cord-006870-f5w6fw6q 311 15 vs vs IN cord-006870-f5w6fw6q 311 16 70 70 CD cord-006870-f5w6fw6q 311 17 % % NN cord-006870-f5w6fw6q 311 18 , , , cord-006870-f5w6fw6q 311 19 p=0.47 p=0.47 NNP cord-006870-f5w6fw6q 311 20 ) ) -RRB- cord-006870-f5w6fw6q 311 21 . . . cord-006870-f5w6fw6q 312 1 At at IN cord-006870-f5w6fw6q 312 2 our -PRON- PRP$ cord-006870-f5w6fw6q 312 3 institution institution NN cord-006870-f5w6fw6q 312 4 , , , cord-006870-f5w6fw6q 312 5 BD BD NNP cord-006870-f5w6fw6q 312 6 declaration declaration NN cord-006870-f5w6fw6q 312 7 was be VBD cord-006870-f5w6fw6q 312 8 more more RBR cord-006870-f5w6fw6q 312 9 often often RB cord-006870-f5w6fw6q 312 10 done do VBN cord-006870-f5w6fw6q 312 11 by by IN cord-006870-f5w6fw6q 312 12 DBD DBD NNP cord-006870-f5w6fw6q 312 13 exams exam NNS cord-006870-f5w6fw6q 312 14 , , , cord-006870-f5w6fw6q 312 15 although although IN cord-006870-f5w6fw6q 312 16 the the DT cord-006870-f5w6fw6q 312 17 primary primary JJ cord-006870-f5w6fw6q 312 18 diagnosis diagnosis NN cord-006870-f5w6fw6q 312 19 and and CC cord-006870-f5w6fw6q 312 20 the the DT cord-006870-f5w6fw6q 312 21 unit unit NN cord-006870-f5w6fw6q 312 22 of of IN cord-006870-f5w6fw6q 312 23 admission admission NN cord-006870-f5w6fw6q 312 24 influenced influence VBD cord-006870-f5w6fw6q 312 25 the the DT cord-006870-f5w6fw6q 312 26 decision decision NN cord-006870-f5w6fw6q 312 27 . . . cord-006870-f5w6fw6q 313 1 An an DT cord-006870-f5w6fw6q 313 2 increased increase VBN cord-006870-f5w6fw6q 313 3 adoption adoption NN cord-006870-f5w6fw6q 313 4 of of IN cord-006870-f5w6fw6q 313 5 SBD SBD NNP cord-006870-f5w6fw6q 313 6 exams exam NNS cord-006870-f5w6fw6q 313 7 was be VBD cord-006870-f5w6fw6q 313 8 noted note VBN cord-006870-f5w6fw6q 313 9 after after IN cord-006870-f5w6fw6q 313 10 the the DT cord-006870-f5w6fw6q 313 11 2010 2010 CD cord-006870-f5w6fw6q 313 12 AAN AAN NNP cord-006870-f5w6fw6q 313 13 BD BD NNP cord-006870-f5w6fw6q 313 14 Guidelines Guidelines NNP cord-006870-f5w6fw6q 313 15 , , , cord-006870-f5w6fw6q 313 16 supporting support VBG cord-006870-f5w6fw6q 313 17 SBD SBD NNP cord-006870-f5w6fw6q 313 18 exam exam NN cord-006870-f5w6fw6q 313 19 , , , cord-006870-f5w6fw6q 313 20 were be VBD cord-006870-f5w6fw6q 313 21 published publish VBN cord-006870-f5w6fw6q 313 22 . . . cord-006870-f5w6fw6q 314 1 Although although IN cord-006870-f5w6fw6q 314 2 the the DT cord-006870-f5w6fw6q 314 3 number number NN cord-006870-f5w6fw6q 314 4 of of IN cord-006870-f5w6fw6q 314 5 exams exam NNS cord-006870-f5w6fw6q 314 6 did do VBD cord-006870-f5w6fw6q 314 7 not not RB cord-006870-f5w6fw6q 314 8 affect affect VB cord-006870-f5w6fw6q 314 9 rate rate NN cord-006870-f5w6fw6q 314 10 of of IN cord-006870-f5w6fw6q 314 11 consent consent NN cord-006870-f5w6fw6q 314 12 for for IN cord-006870-f5w6fw6q 314 13 donation donation NN cord-006870-f5w6fw6q 314 14 , , , cord-006870-f5w6fw6q 314 15 surrogate surrogate JJ cord-006870-f5w6fw6q 314 16 markers marker NNS cord-006870-f5w6fw6q 314 17 indicated indicate VBD cord-006870-f5w6fw6q 314 18 better well JJR cord-006870-f5w6fw6q 314 19 function function NN cord-006870-f5w6fw6q 314 20 of of IN cord-006870-f5w6fw6q 314 21 organs organ NNS cord-006870-f5w6fw6q 314 22 after after IN cord-006870-f5w6fw6q 314 23 SBD SBD NNP cord-006870-f5w6fw6q 314 24 , , , cord-006870-f5w6fw6q 314 25 while while IN cord-006870-f5w6fw6q 314 26 DBD DBD NNP cord-006870-f5w6fw6q 314 27 patients patient NNS cord-006870-f5w6fw6q 314 28 stayed stay VBD cord-006870-f5w6fw6q 314 29 in in IN cord-006870-f5w6fw6q 314 30 the the DT cord-006870-f5w6fw6q 314 31 ICUs ICUs NNP cord-006870-f5w6fw6q 314 32 over over IN cord-006870-f5w6fw6q 314 33 a a DT cord-006870-f5w6fw6q 314 34 day day NN cord-006870-f5w6fw6q 314 35 longer long RBR cord-006870-f5w6fw6q 314 36 . . . cord-006870-f5w6fw6q 315 1 There there EX cord-006870-f5w6fw6q 315 2 are be VBP cord-006870-f5w6fw6q 315 3 no no DT cord-006870-f5w6fw6q 315 4 data data NN cord-006870-f5w6fw6q 315 5 supporting support VBG cord-006870-f5w6fw6q 315 6 better well JJR cord-006870-f5w6fw6q 315 7 numbers number NNS cord-006870-f5w6fw6q 315 8 or or CC cord-006870-f5w6fw6q 315 9 function function NN cord-006870-f5w6fw6q 315 10 of of IN cord-006870-f5w6fw6q 315 11 organs organ NNS cord-006870-f5w6fw6q 315 12 in in IN cord-006870-f5w6fw6q 315 13 donors donor NNS cord-006870-f5w6fw6q 315 14 after after IN cord-006870-f5w6fw6q 315 15 brain brain NN cord-006870-f5w6fw6q 315 16 death death NN cord-006870-f5w6fw6q 315 17 ( ( -LRB- cord-006870-f5w6fw6q 315 18 BD BD NNP cord-006870-f5w6fw6q 315 19 ) ) -RRB- cord-006870-f5w6fw6q 315 20 , , , cord-006870-f5w6fw6q 315 21 if if IN cord-006870-f5w6fw6q 315 22 there there EX cord-006870-f5w6fw6q 315 23 is be VBZ cord-006870-f5w6fw6q 315 24 a a DT cord-006870-f5w6fw6q 315 25 shorter short JJR cord-006870-f5w6fw6q 315 26 waiting waiting NN cord-006870-f5w6fw6q 315 27 period period NN cord-006870-f5w6fw6q 315 28 ( ( -LRB- cord-006870-f5w6fw6q 315 29 as as IN cord-006870-f5w6fw6q 315 30 expected expect VBN cord-006870-f5w6fw6q 315 31 with with IN cord-006870-f5w6fw6q 315 32 single single JJ cord-006870-f5w6fw6q 315 33 brain brain NN cord-006870-f5w6fw6q 315 34 death death NN cord-006870-f5w6fw6q 315 35 exam exam NN cord-006870-f5w6fw6q 315 36 [ [ -LRB- cord-006870-f5w6fw6q 315 37 SBD SBD NNP cord-006870-f5w6fw6q 315 38 ] ] -RRB- cord-006870-f5w6fw6q 315 39 ) ) -RRB- cord-006870-f5w6fw6q 315 40 from from IN cord-006870-f5w6fw6q 315 41 the the DT cord-006870-f5w6fw6q 315 42 time time NN cord-006870-f5w6fw6q 315 43 that that WDT cord-006870-f5w6fw6q 315 44 BD BD NNP cord-006870-f5w6fw6q 315 45 is be VBZ cord-006870-f5w6fw6q 315 46 declared declare VBN cord-006870-f5w6fw6q 315 47 to to IN cord-006870-f5w6fw6q 315 48 the the DT cord-006870-f5w6fw6q 315 49 time time NN cord-006870-f5w6fw6q 315 50 the the DT cord-006870-f5w6fw6q 315 51 patient patient NN cord-006870-f5w6fw6q 315 52 arrives arrive VBZ cord-006870-f5w6fw6q 315 53 at at IN cord-006870-f5w6fw6q 315 54 the the DT cord-006870-f5w6fw6q 315 55 operating operating NN cord-006870-f5w6fw6q 315 56 room room NN cord-006870-f5w6fw6q 315 57 ( ( -LRB- cord-006870-f5w6fw6q 315 58 OR OR NNP cord-006870-f5w6fw6q 315 59 ) ) -RRB- cord-006870-f5w6fw6q 315 60 . . . cord-006870-f5w6fw6q 316 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 316 2 goal goal NN cord-006870-f5w6fw6q 316 3 was be VBD cord-006870-f5w6fw6q 316 4 to to TO cord-006870-f5w6fw6q 316 5 find find VB cord-006870-f5w6fw6q 316 6 if if IN cord-006870-f5w6fw6q 316 7 the the DT cord-006870-f5w6fw6q 316 8 number number NN cord-006870-f5w6fw6q 316 9 of of IN cord-006870-f5w6fw6q 316 10 brain brain NN cord-006870-f5w6fw6q 316 11 death death NN cord-006870-f5w6fw6q 316 12 exams exam NNS cord-006870-f5w6fw6q 316 13 , , , cord-006870-f5w6fw6q 316 14 either either CC cord-006870-f5w6fw6q 316 15 SBD SBD NNP cord-006870-f5w6fw6q 316 16 or or CC cord-006870-f5w6fw6q 316 17 dual dual JJ cord-006870-f5w6fw6q 316 18 ( ( -LRB- cord-006870-f5w6fw6q 316 19 DBD DBD NNP cord-006870-f5w6fw6q 316 20 ) ) -RRB- cord-006870-f5w6fw6q 316 21 , , , cord-006870-f5w6fw6q 316 22 had have VBD cord-006870-f5w6fw6q 316 23 any any DT cord-006870-f5w6fw6q 316 24 impact impact NN cord-006870-f5w6fw6q 316 25 on on IN cord-006870-f5w6fw6q 316 26 the the DT cord-006870-f5w6fw6q 316 27 number number NN cord-006870-f5w6fw6q 316 28 of of IN cord-006870-f5w6fw6q 316 29 organs organ NNS cord-006870-f5w6fw6q 316 30 recovered recover VBN cord-006870-f5w6fw6q 316 31 and and CC cord-006870-f5w6fw6q 316 32 transplanted transplant VBN cord-006870-f5w6fw6q 317 1 We -PRON- PRP cord-006870-f5w6fw6q 317 2 evaluated evaluate VBD cord-006870-f5w6fw6q 317 3 our -PRON- PRP$ cord-006870-f5w6fw6q 317 4 hospital hospital NN cord-006870-f5w6fw6q 317 5 's 's POS cord-006870-f5w6fw6q 317 6 BD BD NNP cord-006870-f5w6fw6q 317 7 registry registry NN cord-006870-f5w6fw6q 317 8 between between IN cord-006870-f5w6fw6q 317 9 January January NNP cord-006870-f5w6fw6q 317 10 2006 2006 CD cord-006870-f5w6fw6q 317 11 and and CC cord-006870-f5w6fw6q 317 12 June June NNP cord-006870-f5w6fw6q 317 13 2017 2017 CD cord-006870-f5w6fw6q 317 14 regarding regard VBG cord-006870-f5w6fw6q 317 15 SBD SBD NNP cord-006870-f5w6fw6q 317 16 or or CC cord-006870-f5w6fw6q 317 17 DBD DBD NNP cord-006870-f5w6fw6q 317 18 and and CC cord-006870-f5w6fw6q 317 19 cross cross NN cord-006870-f5w6fw6q 317 20 - - JJ cord-006870-f5w6fw6q 317 21 matched match VBN cord-006870-f5w6fw6q 317 22 our -PRON- PRP$ cord-006870-f5w6fw6q 317 23 electronic electronic JJ cord-006870-f5w6fw6q 317 24 medical medical JJ cord-006870-f5w6fw6q 317 25 records record NNS cord-006870-f5w6fw6q 317 26 with with IN cord-006870-f5w6fw6q 317 27 the the DT cord-006870-f5w6fw6q 317 28 records record NNS cord-006870-f5w6fw6q 317 29 of of IN cord-006870-f5w6fw6q 317 30 the the DT cord-006870-f5w6fw6q 317 31 local local JJ cord-006870-f5w6fw6q 317 32 organ organ NN cord-006870-f5w6fw6q 317 33 procurement procurement NN cord-006870-f5w6fw6q 317 34 organization organization NN cord-006870-f5w6fw6q 317 35 Out out IN cord-006870-f5w6fw6q 317 36 of of IN cord-006870-f5w6fw6q 317 37 251 251 CD cord-006870-f5w6fw6q 317 38 BD BD NNP cord-006870-f5w6fw6q 317 39 declarations declaration NNS cord-006870-f5w6fw6q 317 40 , , , cord-006870-f5w6fw6q 317 41 150 150 CD cord-006870-f5w6fw6q 317 42 led lead VBD cord-006870-f5w6fw6q 317 43 to to IN cord-006870-f5w6fw6q 317 44 consent consent NN cord-006870-f5w6fw6q 317 45 , , , cord-006870-f5w6fw6q 317 46 of of IN cord-006870-f5w6fw6q 317 47 which which WDT cord-006870-f5w6fw6q 317 48 74 74 CD cord-006870-f5w6fw6q 317 49 ( ( -LRB- cord-006870-f5w6fw6q 317 50 49.3 49.3 CD cord-006870-f5w6fw6q 317 51 % % NN cord-006870-f5w6fw6q 317 52 ) ) -RRB- cord-006870-f5w6fw6q 317 53 after after IN cord-006870-f5w6fw6q 317 54 SBD SBD NNP cord-006870-f5w6fw6q 317 55 and and CC cord-006870-f5w6fw6q 317 56 76 76 CD cord-006870-f5w6fw6q 317 57 ( ( -LRB- cord-006870-f5w6fw6q 317 58 50.7 50.7 CD cord-006870-f5w6fw6q 317 59 % % NN cord-006870-f5w6fw6q 317 60 ) ) -RRB- cord-006870-f5w6fw6q 317 61 after after IN cord-006870-f5w6fw6q 317 62 DBD DBD NNP cord-006870-f5w6fw6q 317 63 . . . cord-006870-f5w6fw6q 318 1 There there EX cord-006870-f5w6fw6q 318 2 was be VBD cord-006870-f5w6fw6q 318 3 a a DT cord-006870-f5w6fw6q 318 4 trend trend NN cord-006870-f5w6fw6q 318 5 for for IN cord-006870-f5w6fw6q 318 6 longer long JJR cord-006870-f5w6fw6q 318 7 consent consent NN cord-006870-f5w6fw6q 318 8 to to IN cord-006870-f5w6fw6q 318 9 OR or CC cord-006870-f5w6fw6q 318 10 time time NN cord-006870-f5w6fw6q 318 11 for for IN cord-006870-f5w6fw6q 318 12 DBD DBD NNP cord-006870-f5w6fw6q 318 13 ( ( -LRB- cord-006870-f5w6fw6q 318 14 41.7 41.7 CD cord-006870-f5w6fw6q 318 15 ± ± CD cord-006870-f5w6fw6q 318 16 20.1 20.1 CD cord-006870-f5w6fw6q 318 17 hours hour NNS cord-006870-f5w6fw6q 318 18 vs vs IN cord-006870-f5w6fw6q 318 19 36.4 36.4 CD cord-006870-f5w6fw6q 318 20 ± ± CD cord-006870-f5w6fw6q 318 21 13.7 13.7 CD cord-006870-f5w6fw6q 318 22 for for IN cord-006870-f5w6fw6q 318 23 SBD SBD NNP cord-006870-f5w6fw6q 318 24 , , , cord-006870-f5w6fw6q 318 25 p=0.07 p=0.07 NNP cord-006870-f5w6fw6q 318 26 ) ) -RRB- cord-006870-f5w6fw6q 318 27 . . . cord-006870-f5w6fw6q 319 1 There there EX cord-006870-f5w6fw6q 319 2 was be VBD cord-006870-f5w6fw6q 319 3 no no DT cord-006870-f5w6fw6q 319 4 difference difference NN cord-006870-f5w6fw6q 319 5 in in IN cord-006870-f5w6fw6q 319 6 the the DT cord-006870-f5w6fw6q 319 7 number number NN cord-006870-f5w6fw6q 319 8 of of IN cord-006870-f5w6fw6q 319 9 organs organ NNS cord-006870-f5w6fw6q 319 10 recovered recover VBN cord-006870-f5w6fw6q 319 11 or or CC cord-006870-f5w6fw6q 319 12 transplanted transplant VBN cord-006870-f5w6fw6q 319 13 based base VBN cord-006870-f5w6fw6q 319 14 on on IN cord-006870-f5w6fw6q 319 15 the the DT cord-006870-f5w6fw6q 319 16 number number NN cord-006870-f5w6fw6q 319 17 of of IN cord-006870-f5w6fw6q 319 18 exams exam NNS cord-006870-f5w6fw6q 319 19 ( ( -LRB- cord-006870-f5w6fw6q 319 20 4.0 4.0 CD cord-006870-f5w6fw6q 319 21 ± ± CD cord-006870-f5w6fw6q 319 22 1.8 1.8 CD cord-006870-f5w6fw6q 319 23 vs vs IN cord-006870-f5w6fw6q 319 24 3.7 3.7 CD cord-006870-f5w6fw6q 319 25 ± ± CD cord-006870-f5w6fw6q 319 26 1.8 1.8 CD cord-006870-f5w6fw6q 319 27 organs organ NNS cord-006870-f5w6fw6q 319 28 / / SYM cord-006870-f5w6fw6q 319 29 patient patient NN cord-006870-f5w6fw6q 319 30 recovered recover VBD cord-006870-f5w6fw6q 319 31 and and CC cord-006870-f5w6fw6q 319 32 3.2 3.2 CD cord-006870-f5w6fw6q 319 33 ± ± NNP cord-006870-f5w6fw6q 319 34 2.0 2.0 CD cord-006870-f5w6fw6q 319 35 vs vs IN cord-006870-f5w6fw6q 319 36 2.8 2.8 CD cord-006870-f5w6fw6q 319 37 ± ± CD cord-006870-f5w6fw6q 319 38 1.9 1.9 CD cord-006870-f5w6fw6q 319 39 transplanted transplant VBD cord-006870-f5w6fw6q 319 40 for for IN cord-006870-f5w6fw6q 319 41 SBD SBD NNP cord-006870-f5w6fw6q 319 42 vs vs IN cord-006870-f5w6fw6q 319 43 DBD DBD NNP cord-006870-f5w6fw6q 319 44 , , , cord-006870-f5w6fw6q 319 45 respectively respectively RB cord-006870-f5w6fw6q 319 46 , , , cord-006870-f5w6fw6q 319 47 p>0.05 p>0.05 NNP cord-006870-f5w6fw6q 319 48 ) ) -RRB- cord-006870-f5w6fw6q 319 49 . . . cord-006870-f5w6fw6q 320 1 There there EX cord-006870-f5w6fw6q 320 2 was be VBD cord-006870-f5w6fw6q 320 3 a a DT cord-006870-f5w6fw6q 320 4 trend trend NN cord-006870-f5w6fw6q 320 5 for for IN cord-006870-f5w6fw6q 320 6 more more JJR cord-006870-f5w6fw6q 320 7 lungs lung NNS cord-006870-f5w6fw6q 320 8 to to TO cord-006870-f5w6fw6q 320 9 be be VB cord-006870-f5w6fw6q 320 10 transplanted transplant VBN cord-006870-f5w6fw6q 320 11 after after IN cord-006870-f5w6fw6q 320 12 SBD SBD NNP cord-006870-f5w6fw6q 320 13 exam exam NN cord-006870-f5w6fw6q 320 14 ( ( -LRB- cord-006870-f5w6fw6q 320 15 62 62 CD cord-006870-f5w6fw6q 320 16 % % NN cord-006870-f5w6fw6q 320 17 vs vs IN cord-006870-f5w6fw6q 320 18 44 44 CD cord-006870-f5w6fw6q 320 19 % % NN cord-006870-f5w6fw6q 320 20 , , , cord-006870-f5w6fw6q 320 21 p=0.06 p=0.06 NNP cord-006870-f5w6fw6q 320 22 ) ) -RRB- cord-006870-f5w6fw6q 320 23 , , , cord-006870-f5w6fw6q 320 24 but but CC cord-006870-f5w6fw6q 320 25 this this DT cord-006870-f5w6fw6q 320 26 was be VBD cord-006870-f5w6fw6q 320 27 not not RB cord-006870-f5w6fw6q 320 28 found find VBN cord-006870-f5w6fw6q 320 29 with with IN cord-006870-f5w6fw6q 320 30 kidneys kidney NNS cord-006870-f5w6fw6q 320 31 , , , cord-006870-f5w6fw6q 320 32 heart heart NN cord-006870-f5w6fw6q 320 33 , , , cord-006870-f5w6fw6q 320 34 liver liver NN cord-006870-f5w6fw6q 320 35 , , , cord-006870-f5w6fw6q 320 36 pancreas pancreas NN cord-006870-f5w6fw6q 320 37 or or CC cord-006870-f5w6fw6q 320 38 intestines intestine NNS cord-006870-f5w6fw6q 320 39 . . . cord-006870-f5w6fw6q 321 1 In in IN cord-006870-f5w6fw6q 321 2 multiple multiple JJ cord-006870-f5w6fw6q 321 3 logistic logistic JJ cord-006870-f5w6fw6q 321 4 regression regression NN cord-006870-f5w6fw6q 321 5 models model NNS cord-006870-f5w6fw6q 321 6 , , , cord-006870-f5w6fw6q 321 7 adjusting adjust VBG cord-006870-f5w6fw6q 321 8 for for IN cord-006870-f5w6fw6q 321 9 variables variable NNS cord-006870-f5w6fw6q 321 10 pertinent pertinent JJ cord-006870-f5w6fw6q 321 11 to to IN cord-006870-f5w6fw6q 321 12 each each DT cord-006870-f5w6fw6q 321 13 individual individual JJ cord-006870-f5w6fw6q 321 14 organ organ NN cord-006870-f5w6fw6q 321 15 function function NN cord-006870-f5w6fw6q 321 16 ( ( -LRB- cord-006870-f5w6fw6q 321 17 for for IN cord-006870-f5w6fw6q 321 18 example example NN cord-006870-f5w6fw6q 321 19 , , , cord-006870-f5w6fw6q 321 20 BUN bun NN cord-006870-f5w6fw6q 321 21 or or CC cord-006870-f5w6fw6q 321 22 creatinine creatinine NN cord-006870-f5w6fw6q 321 23 level level NN cord-006870-f5w6fw6q 321 24 for for IN cord-006870-f5w6fw6q 321 25 kidneys kidney NNS cord-006870-f5w6fw6q 321 26 , , , cord-006870-f5w6fw6q 321 27 blood blood NN cord-006870-f5w6fw6q 321 28 gases gas NNS cord-006870-f5w6fw6q 321 29 for for IN cord-006870-f5w6fw6q 321 30 lungs lung NNS cord-006870-f5w6fw6q 321 31 etc etc FW cord-006870-f5w6fw6q 321 32 ) ) -RRB- cord-006870-f5w6fw6q 321 33 , , , cord-006870-f5w6fw6q 321 34 the the DT cord-006870-f5w6fw6q 321 35 number number NN cord-006870-f5w6fw6q 321 36 of of IN cord-006870-f5w6fw6q 321 37 exams exam NNS cord-006870-f5w6fw6q 321 38 was be VBD cord-006870-f5w6fw6q 321 39 not not RB cord-006870-f5w6fw6q 321 40 an an DT cord-006870-f5w6fw6q 321 41 independent independent JJ cord-006870-f5w6fw6q 321 42 predictor predictor NN cord-006870-f5w6fw6q 321 43 for for IN cord-006870-f5w6fw6q 321 44 successful successful JJ cord-006870-f5w6fw6q 321 45 transplantation transplantation NN cord-006870-f5w6fw6q 322 1 Conclusions conclusion NNS cord-006870-f5w6fw6q 322 2 SBD SBD NNP cord-006870-f5w6fw6q 322 3 exam exam NN cord-006870-f5w6fw6q 322 4 led lead VBD cord-006870-f5w6fw6q 322 5 to to IN cord-006870-f5w6fw6q 322 6 similar similar JJ cord-006870-f5w6fw6q 322 7 numbers number NNS cord-006870-f5w6fw6q 322 8 of of IN cord-006870-f5w6fw6q 322 9 organs organ NNS cord-006870-f5w6fw6q 322 10 transplanted transplant VBN cord-006870-f5w6fw6q 322 11 compared compare VBN cord-006870-f5w6fw6q 322 12 to to IN cord-006870-f5w6fw6q 322 13 DBD DBD NNP cord-006870-f5w6fw6q 322 14 exam exam NN cord-006870-f5w6fw6q 322 15 in in IN cord-006870-f5w6fw6q 322 16 this this DT cord-006870-f5w6fw6q 322 17 single single JJ cord-006870-f5w6fw6q 322 18 center center NN cord-006870-f5w6fw6q 322 19 registry registry NN cord-006870-f5w6fw6q 322 20 analysis analysis NN cord-006870-f5w6fw6q 322 21 . . . cord-006870-f5w6fw6q 323 1 More more RBR cord-006870-f5w6fw6q 323 2 rapid rapid JJ cord-006870-f5w6fw6q 323 3 brain brain NN cord-006870-f5w6fw6q 323 4 death death NN cord-006870-f5w6fw6q 323 5 declaration declaration NN cord-006870-f5w6fw6q 323 6 , , , cord-006870-f5w6fw6q 323 7 as as IN cord-006870-f5w6fw6q 323 8 with with IN cord-006870-f5w6fw6q 323 9 SBD SBD NNP cord-006870-f5w6fw6q 323 10 , , , cord-006870-f5w6fw6q 323 11 is be VBZ cord-006870-f5w6fw6q 323 12 not not RB cord-006870-f5w6fw6q 323 13 a a DT cord-006870-f5w6fw6q 323 14 factor factor NN cord-006870-f5w6fw6q 323 15 that that WDT cord-006870-f5w6fw6q 323 16 influences influence VBZ cord-006870-f5w6fw6q 323 17 organ organ NN cord-006870-f5w6fw6q 323 18 transplantation transplantation NN cord-006870-f5w6fw6q 324 1 The the DT cord-006870-f5w6fw6q 324 2 Glasgow Glasgow NNP cord-006870-f5w6fw6q 324 3 Coma Coma NNP cord-006870-f5w6fw6q 324 4 Scale Scale NNP cord-006870-f5w6fw6q 324 5 ( ( -LRB- cord-006870-f5w6fw6q 324 6 GCS GCS NNP cord-006870-f5w6fw6q 324 7 ) ) -RRB- cord-006870-f5w6fw6q 324 8 is be VBZ cord-006870-f5w6fw6q 324 9 a a DT cord-006870-f5w6fw6q 324 10 standardized standardized JJ cord-006870-f5w6fw6q 324 11 and and CC cord-006870-f5w6fw6q 324 12 commonly commonly RB cord-006870-f5w6fw6q 324 13 used use VBN cord-006870-f5w6fw6q 324 14 way way NN cord-006870-f5w6fw6q 324 15 of of IN cord-006870-f5w6fw6q 324 16 assessing assess VBG cord-006870-f5w6fw6q 324 17 important important JJ cord-006870-f5w6fw6q 324 18 aspects aspect NNS cord-006870-f5w6fw6q 324 19 of of IN cord-006870-f5w6fw6q 324 20 neurological neurological JJ cord-006870-f5w6fw6q 324 21 condition condition NN cord-006870-f5w6fw6q 324 22 for for IN cord-006870-f5w6fw6q 324 23 critically critically RB cord-006870-f5w6fw6q 324 24 ill ill JJ cord-006870-f5w6fw6q 324 25 patients patient NNS cord-006870-f5w6fw6q 324 26 . . . cord-006870-f5w6fw6q 325 1 While while IN cord-006870-f5w6fw6q 325 2 it -PRON- PRP cord-006870-f5w6fw6q 325 3 is be VBZ cord-006870-f5w6fw6q 325 4 a a DT cord-006870-f5w6fw6q 325 5 validated validated JJ cord-006870-f5w6fw6q 325 6 tool tool NN cord-006870-f5w6fw6q 325 7 for for IN cord-006870-f5w6fw6q 325 8 prognostication prognostication NN cord-006870-f5w6fw6q 325 9 , , , cord-006870-f5w6fw6q 325 10 it -PRON- PRP cord-006870-f5w6fw6q 325 11 is be VBZ cord-006870-f5w6fw6q 325 12 unclear unclear JJ cord-006870-f5w6fw6q 325 13 whether whether IN cord-006870-f5w6fw6q 325 14 serial serial JJ cord-006870-f5w6fw6q 325 15 measurements measurement NNS cord-006870-f5w6fw6q 325 16 add add VBP cord-006870-f5w6fw6q 325 17 value value NN cord-006870-f5w6fw6q 325 18 to to IN cord-006870-f5w6fw6q 325 19 this this DT cord-006870-f5w6fw6q 325 20 prognosis prognosis NN cord-006870-f5w6fw6q 325 21 . . . cord-006870-f5w6fw6q 326 1 We -PRON- PRP cord-006870-f5w6fw6q 326 2 used use VBD cord-006870-f5w6fw6q 326 3 a a DT cord-006870-f5w6fw6q 326 4 large large JJ cord-006870-f5w6fw6q 326 5 set set NN cord-006870-f5w6fw6q 326 6 of of IN cord-006870-f5w6fw6q 326 7 serially serially RB cord-006870-f5w6fw6q 326 8 collected collect VBN cord-006870-f5w6fw6q 326 9 GCS GCS NNP cord-006870-f5w6fw6q 326 10 measurements measurement NNS cord-006870-f5w6fw6q 326 11 to to TO cord-006870-f5w6fw6q 326 12 assess assess VB cord-006870-f5w6fw6q 326 13 the the DT cord-006870-f5w6fw6q 326 14 impact impact NN cord-006870-f5w6fw6q 326 15 of of IN cord-006870-f5w6fw6q 326 16 GCS GCS NNP cord-006870-f5w6fw6q 326 17 score score NN cord-006870-f5w6fw6q 326 18 on on IN cord-006870-f5w6fw6q 326 19 the the DT cord-006870-f5w6fw6q 326 20 trajectory trajectory NN cord-006870-f5w6fw6q 326 21 of of IN cord-006870-f5w6fw6q 326 22 neurological neurological JJ cord-006870-f5w6fw6q 326 23 recovery recovery NN cord-006870-f5w6fw6q 326 24 as as RB cord-006870-f5w6fw6q 326 25 well well RB cord-006870-f5w6fw6q 326 26 as as IN cord-006870-f5w6fw6q 326 27 factors factor NNS cord-006870-f5w6fw6q 326 28 affecting affect VBG cord-006870-f5w6fw6q 326 29 score score NN cord-006870-f5w6fw6q 326 30 variance variance NN cord-006870-f5w6fw6q 326 31 . . . cord-006870-f5w6fw6q 327 1 GCS GCS NNP cord-006870-f5w6fw6q 327 2 total total NN cord-006870-f5w6fw6q 327 3 and and CC cord-006870-f5w6fw6q 327 4 subscores subscore NNS cord-006870-f5w6fw6q 327 5 ( ( -LRB- cord-006870-f5w6fw6q 327 6 483,041 483,041 CD cord-006870-f5w6fw6q 327 7 time time NN cord-006870-f5w6fw6q 327 8 points point VBZ cord-006870-f5w6fw6q 327 9 from from IN cord-006870-f5w6fw6q 327 10 5,456 5,456 CD cord-006870-f5w6fw6q 327 11 patients patient NNS cord-006870-f5w6fw6q 327 12 ) ) -RRB- cord-006870-f5w6fw6q 327 13 recorded record VBN cord-006870-f5w6fw6q 327 14 hourly hourly RB cord-006870-f5w6fw6q 327 15 by by IN cord-006870-f5w6fw6q 327 16 registered register VBN cord-006870-f5w6fw6q 327 17 nurses nurse NNS cord-006870-f5w6fw6q 327 18 in in IN cord-006870-f5w6fw6q 327 19 the the DT cord-006870-f5w6fw6q 327 20 Neurosurgical Neurosurgical NNP cord-006870-f5w6fw6q 327 21 Intensive Intensive NNP cord-006870-f5w6fw6q 327 22 Care Care NNP cord-006870-f5w6fw6q 327 23 Unit Unit NNP cord-006870-f5w6fw6q 327 24 ( ( -LRB- cord-006870-f5w6fw6q 327 25 NSICU NSICU NNP cord-006870-f5w6fw6q 327 26 ) ) -RRB- cord-006870-f5w6fw6q 327 27 between between IN cord-006870-f5w6fw6q 327 28 January January NNP cord-006870-f5w6fw6q 327 29 , , , cord-006870-f5w6fw6q 327 30 2012 2012 CD cord-006870-f5w6fw6q 327 31 and and CC cord-006870-f5w6fw6q 327 32 May May NNP cord-006870-f5w6fw6q 327 33 , , , cord-006870-f5w6fw6q 327 34 2016 2016 CD cord-006870-f5w6fw6q 327 35 were be VBD cord-006870-f5w6fw6q 327 36 analyzed analyze VBN cord-006870-f5w6fw6q 327 37 retrospectively retrospectively RB cord-006870-f5w6fw6q 327 38 . . . cord-006870-f5w6fw6q 328 1 K K NNP cord-006870-f5w6fw6q 328 2 - - HYPH cord-006870-f5w6fw6q 328 3 means mean NNS cord-006870-f5w6fw6q 328 4 clustering clustering NN cord-006870-f5w6fw6q 328 5 provided provide VBD cord-006870-f5w6fw6q 328 6 groups group NNS cord-006870-f5w6fw6q 328 7 with with IN cord-006870-f5w6fw6q 328 8 similar similar JJ cord-006870-f5w6fw6q 328 9 progression progression NN cord-006870-f5w6fw6q 328 10 characteristics characteristic NNS cord-006870-f5w6fw6q 328 11 during during IN cord-006870-f5w6fw6q 328 12 NSICU NSICU NNP cord-006870-f5w6fw6q 328 13 stay stay VB cord-006870-f5w6fw6q 328 14 . . . cord-006870-f5w6fw6q 329 1 K K NNP cord-006870-f5w6fw6q 329 2 - - HYPH cord-006870-f5w6fw6q 329 3 means mean NNS cord-006870-f5w6fw6q 329 4 clustering clustering NN cord-006870-f5w6fw6q 329 5 provided provide VBD cord-006870-f5w6fw6q 329 6 groups group NNS cord-006870-f5w6fw6q 329 7 with with IN cord-006870-f5w6fw6q 329 8 similar similar JJ cord-006870-f5w6fw6q 329 9 progression progression NN cord-006870-f5w6fw6q 329 10 characteristics characteristic NNS cord-006870-f5w6fw6q 329 11 during during IN cord-006870-f5w6fw6q 329 12 NSICU NSICU NNP cord-006870-f5w6fw6q 329 13 stay stay VB cord-006870-f5w6fw6q 329 14 . . . cord-006870-f5w6fw6q 330 1 Descriptive descriptive JJ cord-006870-f5w6fw6q 330 2 features feature NNS cord-006870-f5w6fw6q 330 3 for for IN cord-006870-f5w6fw6q 330 4 each each DT cord-006870-f5w6fw6q 330 5 cluster cluster NN cord-006870-f5w6fw6q 330 6 were be VBD cord-006870-f5w6fw6q 330 7 binned bin VBN cord-006870-f5w6fw6q 330 8 into into IN cord-006870-f5w6fw6q 330 9 histograms histogram NNS cord-006870-f5w6fw6q 330 10 and and CC cord-006870-f5w6fw6q 330 11 evaluated evaluate VBN cord-006870-f5w6fw6q 330 12 for for IN cord-006870-f5w6fw6q 330 13 similarity similarity NN cord-006870-f5w6fw6q 330 14 using use VBG cord-006870-f5w6fw6q 330 15 2 2 CD cord-006870-f5w6fw6q 330 16 and and CC cord-006870-f5w6fw6q 330 17 Kruskal Kruskal NNP cord-006870-f5w6fw6q 330 18 - - HYPH cord-006870-f5w6fw6q 330 19 Wallis Wallis NNP cord-006870-f5w6fw6q 330 20 tests test NNS cord-006870-f5w6fw6q 330 21 . . . cord-006870-f5w6fw6q 331 1 Linear linear JJ cord-006870-f5w6fw6q 331 2 correlations correlation NNS cord-006870-f5w6fw6q 331 3 of of IN cord-006870-f5w6fw6q 331 4 the the DT cord-006870-f5w6fw6q 331 5 sub sub NN cord-006870-f5w6fw6q 331 6 - - NNS cord-006870-f5w6fw6q 331 7 scores score NNS cord-006870-f5w6fw6q 331 8 were be VBD cord-006870-f5w6fw6q 331 9 very very RB cord-006870-f5w6fw6q 331 10 high high JJ cord-006870-f5w6fw6q 332 1 ( ( -LRB- cord-006870-f5w6fw6q 332 2 eye eye NN cord-006870-f5w6fw6q 332 3 - - HYPH cord-006870-f5w6fw6q 332 4 verbal verbal JJ cord-006870-f5w6fw6q 332 5 : : : cord-006870-f5w6fw6q 332 6 0.583 0.583 CD cord-006870-f5w6fw6q 332 7 , , . cord-006870-f5w6fw6q 333 1 eye eye NN cord-006870-f5w6fw6q 333 2 - - HYPH cord-006870-f5w6fw6q 333 3 motor motor NN cord-006870-f5w6fw6q 333 4 : : : cord-006870-f5w6fw6q 333 5 0.686 0.686 CD cord-006870-f5w6fw6q 333 6 , , , cord-006870-f5w6fw6q 333 7 verbal verbal JJ cord-006870-f5w6fw6q 333 8 - - HYPH cord-006870-f5w6fw6q 333 9 motor motor NN cord-006870-f5w6fw6q 333 10 : : : cord-006870-f5w6fw6q 333 11 0.583 0.583 CD cord-006870-f5w6fw6q 333 12 ) ) -RRB- cord-006870-f5w6fw6q 333 13 , , , cord-006870-f5w6fw6q 333 14 while while IN cord-006870-f5w6fw6q 333 15 compositional compositional JJ cord-006870-f5w6fw6q 333 16 variance variance NN cord-006870-f5w6fw6q 333 17 was be VBD cord-006870-f5w6fw6q 333 18 low low JJ cord-006870-f5w6fw6q 333 19 for for IN cord-006870-f5w6fw6q 333 20 aggregate aggregate JJ cord-006870-f5w6fw6q 333 21 scores score NNS cord-006870-f5w6fw6q 333 22 . . . cord-006870-f5w6fw6q 334 1 Hour hour NN cord-006870-f5w6fw6q 334 2 - - HYPH cord-006870-f5w6fw6q 334 3 to to IN cord-006870-f5w6fw6q 334 4 - - HYPH cord-006870-f5w6fw6q 334 5 hour hour NN cord-006870-f5w6fw6q 334 6 variance variance NN cord-006870-f5w6fw6q 334 7 in in IN cord-006870-f5w6fw6q 334 8 GCS GCS NNP cord-006870-f5w6fw6q 334 9 correlates correlate VBZ cord-006870-f5w6fw6q 334 10 to to IN cord-006870-f5w6fw6q 334 11 significant significant JJ cord-006870-f5w6fw6q 334 12 NSICU NSICU NNP cord-006870-f5w6fw6q 334 13 activities activity NNS cord-006870-f5w6fw6q 334 14 such such JJ cord-006870-f5w6fw6q 334 15 as as IN cord-006870-f5w6fw6q 334 16 nursing nursing NN cord-006870-f5w6fw6q 334 17 shift shift NN cord-006870-f5w6fw6q 334 18 changes change NNS cord-006870-f5w6fw6q 334 19 . . . cord-006870-f5w6fw6q 335 1 Among among IN cord-006870-f5w6fw6q 335 2 patients patient NNS cord-006870-f5w6fw6q 335 3 with with IN cord-006870-f5w6fw6q 335 4 similar similar JJ cord-006870-f5w6fw6q 335 5 minimum minimum JJ cord-006870-f5w6fw6q 335 6 GCS GCS NNP cord-006870-f5w6fw6q 335 7 scores score NNS cord-006870-f5w6fw6q 335 8 during during IN cord-006870-f5w6fw6q 335 9 their -PRON- PRP$ cord-006870-f5w6fw6q 335 10 stay stay NN cord-006870-f5w6fw6q 335 11 , , , cord-006870-f5w6fw6q 335 12 those those DT cord-006870-f5w6fw6q 335 13 that that WDT cord-006870-f5w6fw6q 335 14 recovered recover VBD cord-006870-f5w6fw6q 335 15 were be VBD cord-006870-f5w6fw6q 335 16 significantly significantly RB cord-006870-f5w6fw6q 335 17 less less RBR cord-006870-f5w6fw6q 335 18 likely likely JJ cord-006870-f5w6fw6q 335 19 to to TO cord-006870-f5w6fw6q 335 20 have have VB cord-006870-f5w6fw6q 335 21 deteriorated deteriorate VBN cord-006870-f5w6fw6q 335 22 in in IN cord-006870-f5w6fw6q 335 23 the the DT cord-006870-f5w6fw6q 335 24 hospital hospital NN cord-006870-f5w6fw6q 335 25 ( ( -LRB- cord-006870-f5w6fw6q 335 26 2 2 CD cord-006870-f5w6fw6q 335 27 , , , cord-006870-f5w6fw6q 335 28 p<<0.0001 p<<0.0001 NNP cord-006870-f5w6fw6q 335 29 ) ) -RRB- cord-006870-f5w6fw6q 335 30 . . . cord-006870-f5w6fw6q 336 1 For for IN cord-006870-f5w6fw6q 336 2 patients patient NNS cord-006870-f5w6fw6q 336 3 with with IN cord-006870-f5w6fw6q 336 4 a a DT cord-006870-f5w6fw6q 336 5 minimum minimum JJ cord-006870-f5w6fw6q 336 6 GCS<=8 gcs<=8 NN cord-006870-f5w6fw6q 336 7 , , , cord-006870-f5w6fw6q 336 8 those those DT cord-006870-f5w6fw6q 336 9 that that WDT cord-006870-f5w6fw6q 336 10 arrived arrive VBD cord-006870-f5w6fw6q 336 11 at at IN cord-006870-f5w6fw6q 336 12 their -PRON- PRP$ cord-006870-f5w6fw6q 336 13 minimum minimum JJ cord-006870-f5w6fw6q 336 14 score score NN cord-006870-f5w6fw6q 336 15 ( ( -LRB- cord-006870-f5w6fw6q 336 16 i.e. i.e. FW cord-006870-f5w6fw6q 336 17 , , , cord-006870-f5w6fw6q 336 18 did do VBD cord-006870-f5w6fw6q 336 19 not not RB cord-006870-f5w6fw6q 336 20 deteriorate deteriorate VB cord-006870-f5w6fw6q 336 21 in in IN cord-006870-f5w6fw6q 336 22 NSICU NSICU NNP cord-006870-f5w6fw6q 336 23 ) ) -RRB- cord-006870-f5w6fw6q 336 24 were be VBD cord-006870-f5w6fw6q 336 25 18.6 18.6 CD cord-006870-f5w6fw6q 336 26 % % NN cord-006870-f5w6fw6q 336 27 more more RBR cord-006870-f5w6fw6q 336 28 likely likely JJ cord-006870-f5w6fw6q 336 29 to to TO cord-006870-f5w6fw6q 336 30 recover recover VB cord-006870-f5w6fw6q 336 31 than than IN cord-006870-f5w6fw6q 336 32 those those DT cord-006870-f5w6fw6q 336 33 who who WP cord-006870-f5w6fw6q 336 34 deteriorated deteriorate VBD cord-006870-f5w6fw6q 336 35 in in IN cord-006870-f5w6fw6q 336 36 - - HYPH cord-006870-f5w6fw6q 336 37 hospital hospital NN cord-006870-f5w6fw6q 336 38 ( ( -LRB- cord-006870-f5w6fw6q 336 39 KW KW NNP cord-006870-f5w6fw6q 336 40 , , , cord-006870-f5w6fw6q 336 41 p<<0.0001 p<<0.0001 NNP cord-006870-f5w6fw6q 336 42 ) ) -RRB- cord-006870-f5w6fw6q 336 43 . . . cord-006870-f5w6fw6q 337 1 Patients patient NNS cord-006870-f5w6fw6q 337 2 that that IN cord-006870-f5w6fw6q 337 3 experienced experience VBD cord-006870-f5w6fw6q 337 4 recovery recovery NN cord-006870-f5w6fw6q 337 5 show show VBP cord-006870-f5w6fw6q 337 6 significantly significantly RB cord-006870-f5w6fw6q 337 7 greater great JJR cord-006870-f5w6fw6q 337 8 improvement improvement NN cord-006870-f5w6fw6q 337 9 as as RB cord-006870-f5w6fw6q 337 10 early early RB cord-006870-f5w6fw6q 337 11 as as IN cord-006870-f5w6fw6q 337 12 2 2 CD cord-006870-f5w6fw6q 337 13 hours hour NNS cord-006870-f5w6fw6q 337 14 after after IN cord-006870-f5w6fw6q 337 15 their -PRON- PRP$ cord-006870-f5w6fw6q 337 16 minimum minimum JJ cord-006870-f5w6fw6q 337 17 score score NN cord-006870-f5w6fw6q 337 18 ( ( -LRB- cord-006870-f5w6fw6q 337 19 KW KW NNP cord-006870-f5w6fw6q 337 20 , , , cord-006870-f5w6fw6q 337 21 p<<0.0001 p<<0.0001 NNP cord-006870-f5w6fw6q 337 22 ) ) -RRB- cord-006870-f5w6fw6q 337 23 . . . cord-006870-f5w6fw6q 338 1 The the DT cord-006870-f5w6fw6q 338 2 GCS GCS NNP cord-006870-f5w6fw6q 338 3 is be VBZ cord-006870-f5w6fw6q 338 4 unnecessarily unnecessarily RB cord-006870-f5w6fw6q 338 5 complex complex JJ cord-006870-f5w6fw6q 338 6 for for IN cord-006870-f5w6fw6q 338 7 most most JJS cord-006870-f5w6fw6q 338 8 NSICU NSICU NNP cord-006870-f5w6fw6q 338 9 patients patient NNS cord-006870-f5w6fw6q 338 10 and and CC cord-006870-f5w6fw6q 338 11 can can MD cord-006870-f5w6fw6q 338 12 be be VB cord-006870-f5w6fw6q 338 13 represented represent VBN cord-006870-f5w6fw6q 338 14 by by IN cord-006870-f5w6fw6q 338 15 fewer few JJR cord-006870-f5w6fw6q 338 16 variables variable NNS cord-006870-f5w6fw6q 338 17 . . . cord-006870-f5w6fw6q 339 1 Serial serial JJ cord-006870-f5w6fw6q 339 2 GCS GCS NNP cord-006870-f5w6fw6q 339 3 measurements measurement NNS cord-006870-f5w6fw6q 339 4 do do VBP cord-006870-f5w6fw6q 339 5 provide provide VB cord-006870-f5w6fw6q 339 6 value value NN cord-006870-f5w6fw6q 339 7 for for IN cord-006870-f5w6fw6q 339 8 prognosis prognosis NN cord-006870-f5w6fw6q 339 9 and and CC cord-006870-f5w6fw6q 339 10 may may MD cord-006870-f5w6fw6q 339 11 be be VB cord-006870-f5w6fw6q 339 12 able able JJ cord-006870-f5w6fw6q 339 13 to to TO cord-006870-f5w6fw6q 339 14 distinguish distinguish VB cord-006870-f5w6fw6q 339 15 patients patient NNS cord-006870-f5w6fw6q 339 16 with with IN cord-006870-f5w6fw6q 339 17 potential potential NN cord-006870-f5w6fw6q 339 18 to to TO cord-006870-f5w6fw6q 339 19 recover recover VB cord-006870-f5w6fw6q 339 20 early early RB cord-006870-f5w6fw6q 339 21 in in IN cord-006870-f5w6fw6q 339 22 their -PRON- PRP$ cord-006870-f5w6fw6q 339 23 hospital hospital NN cord-006870-f5w6fw6q 339 24 course course NN cord-006870-f5w6fw6q 339 25 . . . cord-006870-f5w6fw6q 340 1 Stroke stroke NN cord-006870-f5w6fw6q 340 2 is be VBZ cord-006870-f5w6fw6q 340 3 a a DT cord-006870-f5w6fw6q 340 4 major major JJ cord-006870-f5w6fw6q 340 5 cause cause NN cord-006870-f5w6fw6q 340 6 of of IN cord-006870-f5w6fw6q 340 7 death death NN cord-006870-f5w6fw6q 340 8 and and CC cord-006870-f5w6fw6q 340 9 disability disability NN cord-006870-f5w6fw6q 340 10 , , , cord-006870-f5w6fw6q 340 11 and and CC cord-006870-f5w6fw6q 340 12 common common JJ cord-006870-f5w6fw6q 340 13 admission admission NN cord-006870-f5w6fw6q 340 14 to to IN cord-006870-f5w6fw6q 340 15 neurological neurological JJ cord-006870-f5w6fw6q 340 16 intensive intensive JJ cord-006870-f5w6fw6q 340 17 care care NN cord-006870-f5w6fw6q 340 18 units unit NNS cord-006870-f5w6fw6q 340 19 . . . cord-006870-f5w6fw6q 341 1 Preferences preference NNS cord-006870-f5w6fw6q 341 2 for for IN cord-006870-f5w6fw6q 341 3 cardiopulmonary cardiopulmonary JJ cord-006870-f5w6fw6q 341 4 resuscitation resuscitation NN cord-006870-f5w6fw6q 341 5 ( ( -LRB- cord-006870-f5w6fw6q 341 6 CPR CPR NNP cord-006870-f5w6fw6q 341 7 ) ) -RRB- cord-006870-f5w6fw6q 341 8 are be VBP cord-006870-f5w6fw6q 341 9 often often RB cord-006870-f5w6fw6q 341 10 discussed discuss VBN cord-006870-f5w6fw6q 341 11 , , , cord-006870-f5w6fw6q 341 12 but but CC cord-006870-f5w6fw6q 341 13 there there EX cord-006870-f5w6fw6q 341 14 is be VBZ cord-006870-f5w6fw6q 341 15 limited limited JJ cord-006870-f5w6fw6q 341 16 understanding understanding NN cord-006870-f5w6fw6q 341 17 of of IN cord-006870-f5w6fw6q 341 18 CPR CPR NNP cord-006870-f5w6fw6q 341 19 outcomes outcome NNS cord-006870-f5w6fw6q 341 20 among among IN cord-006870-f5w6fw6q 341 21 stroke stroke NN cord-006870-f5w6fw6q 341 22 patients patient NNS cord-006870-f5w6fw6q 341 23 . . . cord-006870-f5w6fw6q 342 1 Systematic systematic JJ cord-006870-f5w6fw6q 342 2 review review NN cord-006870-f5w6fw6q 342 3 and and CC cord-006870-f5w6fw6q 342 4 meta meta NNP cord-006870-f5w6fw6q 342 5 - - HYPH cord-006870-f5w6fw6q 342 6 analysis analysis NN cord-006870-f5w6fw6q 342 7 of of IN cord-006870-f5w6fw6q 342 8 published publish VBN cord-006870-f5w6fw6q 342 9 literature literature NN cord-006870-f5w6fw6q 342 10 from from IN cord-006870-f5w6fw6q 342 11 1990 1990 CD cord-006870-f5w6fw6q 342 12 to to IN cord-006870-f5w6fw6q 342 13 2016 2016 CD cord-006870-f5w6fw6q 342 14 among among IN cord-006870-f5w6fw6q 342 15 stroke stroke NN cord-006870-f5w6fw6q 342 16 patients patient NNS cord-006870-f5w6fw6q 342 17 undergoing undergo VBG cord-006870-f5w6fw6q 342 18 in in IN cord-006870-f5w6fw6q 342 19 - - HYPH cord-006870-f5w6fw6q 342 20 hospital hospital NN cord-006870-f5w6fw6q 342 21 CPR CPR NNP cord-006870-f5w6fw6q 342 22 . . . cord-006870-f5w6fw6q 343 1 Preferred preferred JJ cord-006870-f5w6fw6q 343 2 Reporting Reporting NNP cord-006870-f5w6fw6q 343 3 Items Items NNPS cord-006870-f5w6fw6q 343 4 for for IN cord-006870-f5w6fw6q 343 5 Systematic Systematic NNP cord-006870-f5w6fw6q 343 6 Reviews Reviews NNPS cord-006870-f5w6fw6q 343 7 and and CC cord-006870-f5w6fw6q 343 8 Meta Meta NNP cord-006870-f5w6fw6q 343 9 - - HYPH cord-006870-f5w6fw6q 343 10 analysis analysis NN cord-006870-f5w6fw6q 343 11 , , , cord-006870-f5w6fw6q 343 12 Metaanalysis Metaanalysis NNP cord-006870-f5w6fw6q 343 13 of of IN cord-006870-f5w6fw6q 343 14 Observational Observational NNP cord-006870-f5w6fw6q 343 15 Studies Studies NNPS cord-006870-f5w6fw6q 343 16 in in IN cord-006870-f5w6fw6q 343 17 Epidemiology Epidemiology NNP cord-006870-f5w6fw6q 343 18 , , , cord-006870-f5w6fw6q 343 19 and and CC cord-006870-f5w6fw6q 343 20 Utstein Utstein NNP cord-006870-f5w6fw6q 343 21 guidelines guideline NNS cord-006870-f5w6fw6q 343 22 were be VBD cord-006870-f5w6fw6q 343 23 used use VBN cord-006870-f5w6fw6q 343 24 to to TO cord-006870-f5w6fw6q 343 25 construct construct VB cord-006870-f5w6fw6q 343 26 standardized standardized JJ cord-006870-f5w6fw6q 343 27 reporting reporting NN cord-006870-f5w6fw6q 343 28 templates template NNS cord-006870-f5w6fw6q 343 29 . . . cord-006870-f5w6fw6q 344 1 Detailed detailed JJ cord-006870-f5w6fw6q 344 2 searches search NNS cord-006870-f5w6fw6q 344 3 of of IN cord-006870-f5w6fw6q 344 4 PubMed PubMed NNP cord-006870-f5w6fw6q 344 5 and and CC cord-006870-f5w6fw6q 344 6 Cochrane Cochrane NNP cord-006870-f5w6fw6q 344 7 libraries library NNS cord-006870-f5w6fw6q 344 8 were be VBD cord-006870-f5w6fw6q 344 9 supplemented supplement VBN cord-006870-f5w6fw6q 344 10 with with IN cord-006870-f5w6fw6q 344 11 hand hand NN cord-006870-f5w6fw6q 344 12 - - HYPH cord-006870-f5w6fw6q 344 13 searched search VBN cord-006870-f5w6fw6q 344 14 bibliographies bibliography NNS cord-006870-f5w6fw6q 344 15 . . . cord-006870-f5w6fw6q 345 1 Primary primary JJ cord-006870-f5w6fw6q 345 2 data datum NNS cord-006870-f5w6fw6q 345 3 from from IN cord-006870-f5w6fw6q 345 4 studies study NNS cord-006870-f5w6fw6q 345 5 meeting meeting NN cord-006870-f5w6fw6q 345 6 inclusion inclusion NN cord-006870-f5w6fw6q 345 7 criteria criterion NNS cord-006870-f5w6fw6q 345 8 at at IN cord-006870-f5w6fw6q 345 9 two two CD cord-006870-f5w6fw6q 345 10 levels level NNS cord-006870-f5w6fw6q 345 11 were be VBD cord-006870-f5w6fw6q 345 12 extracted extract VBN cord-006870-f5w6fw6q 345 13 , , , cord-006870-f5w6fw6q 345 14 i i NN cord-006870-f5w6fw6q 345 15 ) ) -RRB- cord-006870-f5w6fw6q 345 16 survival survival NN cord-006870-f5w6fw6q 345 17 to to IN cord-006870-f5w6fw6q 345 18 hospital hospital NN cord-006870-f5w6fw6q 345 19 discharge discharge NN cord-006870-f5w6fw6q 345 20 after after IN cord-006870-f5w6fw6q 345 21 CPR CPR NNP cord-006870-f5w6fw6q 345 22 , , , cord-006870-f5w6fw6q 345 23 and and CC cord-006870-f5w6fw6q 345 24 stroke stroke NN cord-006870-f5w6fw6q 345 25 as as IN cord-006870-f5w6fw6q 345 26 a a DT cord-006870-f5w6fw6q 345 27 primary primary JJ cord-006870-f5w6fw6q 345 28 admitting admit VBG cord-006870-f5w6fw6q 345 29 diagnosis diagnosis NN cord-006870-f5w6fw6q 345 30 , , , cord-006870-f5w6fw6q 345 31 and and CC cord-006870-f5w6fw6q 345 32 the the DT cord-006870-f5w6fw6q 345 33 less less RBR cord-006870-f5w6fw6q 345 34 restrictive restrictive JJ cord-006870-f5w6fw6q 345 35 , , , cord-006870-f5w6fw6q 345 36 ii ii LS cord-006870-f5w6fw6q 345 37 ) ) -RRB- cord-006870-f5w6fw6q 345 38 survival survival NN cord-006870-f5w6fw6q 345 39 to to IN cord-006870-f5w6fw6q 345 40 hospital hospital NN cord-006870-f5w6fw6q 345 41 discharge discharge NN cord-006870-f5w6fw6q 345 42 after after IN cord-006870-f5w6fw6q 345 43 CPR CPR NNP cord-006870-f5w6fw6q 345 44 with with IN cord-006870-f5w6fw6q 345 45 stroke stroke NN cord-006870-f5w6fw6q 345 46 listed list VBN cord-006870-f5w6fw6q 345 47 as as IN cord-006870-f5w6fw6q 345 48 a a DT cord-006870-f5w6fw6q 345 49 comorbidity comorbidity NN cord-006870-f5w6fw6q 345 50 , , , cord-006870-f5w6fw6q 345 51 were be VBD cord-006870-f5w6fw6q 345 52 meta meta NNP cord-006870-f5w6fw6q 345 53 - - HYPH cord-006870-f5w6fw6q 345 54 analyzed analyze VBN cord-006870-f5w6fw6q 345 55 to to TO cord-006870-f5w6fw6q 345 56 generate generate VB cord-006870-f5w6fw6q 345 57 weighted weighted JJ cord-006870-f5w6fw6q 345 58 , , , cord-006870-f5w6fw6q 345 59 pooled pool VBN cord-006870-f5w6fw6q 345 60 estimates estimate NNS cord-006870-f5w6fw6q 345 61 of of IN cord-006870-f5w6fw6q 345 62 survival survival NN cord-006870-f5w6fw6q 345 63 to to IN cord-006870-f5w6fw6q 345 64 hospital hospital NN cord-006870-f5w6fw6q 345 65 discharge discharge NN cord-006870-f5w6fw6q 345 66 . . . cord-006870-f5w6fw6q 346 1 Of of IN cord-006870-f5w6fw6q 346 2 818 818 CD cord-006870-f5w6fw6q 346 3 articles article NNS cord-006870-f5w6fw6q 346 4 screened screen VBN cord-006870-f5w6fw6q 346 5 , , , cord-006870-f5w6fw6q 346 6 there there EX cord-006870-f5w6fw6q 346 7 were be VBD cord-006870-f5w6fw6q 346 8 176 176 CD cord-006870-f5w6fw6q 346 9 articles article NNS cord-006870-f5w6fw6q 346 10 ( ( -LRB- cord-006870-f5w6fw6q 346 11 22 22 CD cord-006870-f5w6fw6q 346 12 % % NN cord-006870-f5w6fw6q 346 13 ) ) -RRB- cord-006870-f5w6fw6q 346 14 that that WDT cord-006870-f5w6fw6q 346 15 underwent undergo VBD cord-006870-f5w6fw6q 346 16 full full JJ cord-006870-f5w6fw6q 346 17 review review NN cord-006870-f5w6fw6q 346 18 . . . cord-006870-f5w6fw6q 347 1 Three three CD cord-006870-f5w6fw6q 347 2 articles article NNS cord-006870-f5w6fw6q 347 3 met meet VBD cord-006870-f5w6fw6q 347 4 primary primary JJ cord-006870-f5w6fw6q 347 5 inclusion inclusion NN cord-006870-f5w6fw6q 347 6 criteria criterion NNS cord-006870-f5w6fw6q 347 7 , , , cord-006870-f5w6fw6q 347 8 specifically specifically RB cord-006870-f5w6fw6q 347 9 identifying identify VBG cord-006870-f5w6fw6q 347 10 patients patient NNS cord-006870-f5w6fw6q 347 11 with with IN cord-006870-f5w6fw6q 347 12 stroke stroke NN cord-006870-f5w6fw6q 347 13 as as IN cord-006870-f5w6fw6q 347 14 a a DT cord-006870-f5w6fw6q 347 15 primary primary JJ cord-006870-f5w6fw6q 347 16 admitting admit VBG cord-006870-f5w6fw6q 347 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 347 18 . . . cord-006870-f5w6fw6q 348 1 Twenty twenty CD cord-006870-f5w6fw6q 348 2 additional additional JJ cord-006870-f5w6fw6q 348 3 articles article NNS cord-006870-f5w6fw6q 348 4 met meet VBD cord-006870-f5w6fw6q 348 5 secondary secondary JJ cord-006870-f5w6fw6q 348 6 inclusion inclusion NN cord-006870-f5w6fw6q 348 7 criteria criterion NNS cord-006870-f5w6fw6q 348 8 , , , cord-006870-f5w6fw6q 348 9 listing list VBG cord-006870-f5w6fw6q 348 10 stroke stroke NN cord-006870-f5w6fw6q 348 11 as as IN cord-006870-f5w6fw6q 348 12 a a DT cord-006870-f5w6fw6q 348 13 comorbidity comorbidity NN cord-006870-f5w6fw6q 348 14 . . . cord-006870-f5w6fw6q 349 1 There there EX cord-006870-f5w6fw6q 349 2 was be VBD cord-006870-f5w6fw6q 349 3 an an DT cord-006870-f5w6fw6q 349 4 8 8 CD cord-006870-f5w6fw6q 349 5 % % NN cord-006870-f5w6fw6q 349 6 ( ( -LRB- cord-006870-f5w6fw6q 349 7 95 95 CD cord-006870-f5w6fw6q 349 8 % % NN cord-006870-f5w6fw6q 349 9 Confidence confidence NN cord-006870-f5w6fw6q 349 10 Interval interval NN cord-006870-f5w6fw6q 349 11 ( ( -LRB- cord-006870-f5w6fw6q 349 12 CI CI NNP cord-006870-f5w6fw6q 349 13 ) ) -RRB- cord-006870-f5w6fw6q 349 14 0.01 0.01 CD cord-006870-f5w6fw6q 349 15 , , , cord-006870-f5w6fw6q 349 16 0.14 0.14 CD cord-006870-f5w6fw6q 349 17 ) ) -RRB- cord-006870-f5w6fw6q 349 18 rate rate NN cord-006870-f5w6fw6q 349 19 of of IN cord-006870-f5w6fw6q 349 20 survival survival NN cord-006870-f5w6fw6q 349 21 to to IN cord-006870-f5w6fw6q 349 22 hospital hospital NN cord-006870-f5w6fw6q 349 23 discharge discharge NN cord-006870-f5w6fw6q 349 24 rate rate NN cord-006870-f5w6fw6q 349 25 from from IN cord-006870-f5w6fw6q 349 26 a a DT cord-006870-f5w6fw6q 349 27 combined combine VBN cord-006870-f5w6fw6q 349 28 sample sample NN cord-006870-f5w6fw6q 349 29 of of IN cord-006870-f5w6fw6q 349 30 561 561 CD cord-006870-f5w6fw6q 349 31 patients patient NNS cord-006870-f5w6fw6q 349 32 that that WDT cord-006870-f5w6fw6q 349 33 received receive VBD cord-006870-f5w6fw6q 349 34 in in IN cord-006870-f5w6fw6q 349 35 - - HYPH cord-006870-f5w6fw6q 349 36 hospital hospital NN cord-006870-f5w6fw6q 349 37 CPR CPR NNP cord-006870-f5w6fw6q 349 38 . . . cord-006870-f5w6fw6q 350 1 Among among IN cord-006870-f5w6fw6q 350 2 the the DT cord-006870-f5w6fw6q 350 3 more more RBR cord-006870-f5w6fw6q 350 4 heterogenous heterogenous JJ cord-006870-f5w6fw6q 350 5 population population NN cord-006870-f5w6fw6q 350 6 of of IN cord-006870-f5w6fw6q 350 7 inpatients inpatient NNS cord-006870-f5w6fw6q 350 8 with with IN cord-006870-f5w6fw6q 350 9 stroke stroke NN cord-006870-f5w6fw6q 350 10 listed list VBN cord-006870-f5w6fw6q 350 11 as as IN cord-006870-f5w6fw6q 350 12 a a DT cord-006870-f5w6fw6q 350 13 comorbidity comorbidity NN cord-006870-f5w6fw6q 350 14 , , , cord-006870-f5w6fw6q 350 15 there there EX cord-006870-f5w6fw6q 350 16 was be VBD cord-006870-f5w6fw6q 350 17 16 16 CD cord-006870-f5w6fw6q 350 18 % % NN cord-006870-f5w6fw6q 350 19 ( ( -LRB- cord-006870-f5w6fw6q 350 20 95 95 CD cord-006870-f5w6fw6q 350 21 % % NN cord-006870-f5w6fw6q 350 22 CI CI NNP cord-006870-f5w6fw6q 350 23 0.14 0.14 CD cord-006870-f5w6fw6q 350 24 , , , cord-006870-f5w6fw6q 350 25 0.19 0.19 CD cord-006870-f5w6fw6q 350 26 ) ) -RRB- cord-006870-f5w6fw6q 350 27 rate rate NN cord-006870-f5w6fw6q 350 28 of of IN cord-006870-f5w6fw6q 350 29 survival survival NN cord-006870-f5w6fw6q 350 30 to to IN cord-006870-f5w6fw6q 350 31 hospital hospital NN cord-006870-f5w6fw6q 350 32 discharge discharge NN cord-006870-f5w6fw6q 350 33 . . . cord-006870-f5w6fw6q 351 1 Adherence adherence NN cord-006870-f5w6fw6q 351 2 to to IN cord-006870-f5w6fw6q 351 3 Utstein Utstein NNP cord-006870-f5w6fw6q 351 4 reporting reporting NN cord-006870-f5w6fw6q 351 5 guidelines guideline NNS cord-006870-f5w6fw6q 351 6 was be VBD cord-006870-f5w6fw6q 351 7 poor poor JJ cord-006870-f5w6fw6q 351 8 , , , cord-006870-f5w6fw6q 351 9 and and CC cord-006870-f5w6fw6q 351 10 neurological neurological JJ cord-006870-f5w6fw6q 351 11 outcomes outcome NNS cord-006870-f5w6fw6q 351 12 were be VBD cord-006870-f5w6fw6q 351 13 measured measure VBN cord-006870-f5w6fw6q 351 14 in in IN cord-006870-f5w6fw6q 351 15 6 6 CD cord-006870-f5w6fw6q 351 16 ( ( -LRB- cord-006870-f5w6fw6q 351 17 26 26 CD cord-006870-f5w6fw6q 351 18 % % NN cord-006870-f5w6fw6q 351 19 ) ) -RRB- cord-006870-f5w6fw6q 351 20 of of IN cord-006870-f5w6fw6q 351 21 studies study NNS cord-006870-f5w6fw6q 351 22 . . . cord-006870-f5w6fw6q 352 1 Survival survival NN cord-006870-f5w6fw6q 352 2 to to IN cord-006870-f5w6fw6q 352 3 hospital hospital NN cord-006870-f5w6fw6q 352 4 discharge discharge NN cord-006870-f5w6fw6q 352 5 among among IN cord-006870-f5w6fw6q 352 6 stroke stroke NN cord-006870-f5w6fw6q 352 7 patients patient NNS cord-006870-f5w6fw6q 352 8 is be VBZ cord-006870-f5w6fw6q 352 9 lower low JJR cord-006870-f5w6fw6q 352 10 relative relative JJ cord-006870-f5w6fw6q 352 11 to to IN cord-006870-f5w6fw6q 352 12 general general JJ cord-006870-f5w6fw6q 352 13 hospital hospital NN cord-006870-f5w6fw6q 352 14 populations population NNS cord-006870-f5w6fw6q 352 15 . . . cord-006870-f5w6fw6q 353 1 These these DT cord-006870-f5w6fw6q 353 2 preliminary preliminary JJ cord-006870-f5w6fw6q 353 3 findings finding NNS cord-006870-f5w6fw6q 353 4 highlight highlight VBP cord-006870-f5w6fw6q 353 5 the the DT cord-006870-f5w6fw6q 353 6 need need NN cord-006870-f5w6fw6q 353 7 for for IN cord-006870-f5w6fw6q 353 8 improving improve VBG cord-006870-f5w6fw6q 353 9 the the DT cord-006870-f5w6fw6q 353 10 quality quality NN cord-006870-f5w6fw6q 353 11 of of IN cord-006870-f5w6fw6q 353 12 evidence evidence NN cord-006870-f5w6fw6q 353 13 to to TO cord-006870-f5w6fw6q 353 14 inform inform VB cord-006870-f5w6fw6q 353 15 patient patient NN cord-006870-f5w6fw6q 353 16 and and CC cord-006870-f5w6fw6q 353 17 provider provider NN cord-006870-f5w6fw6q 353 18 discussions discussion NNS cord-006870-f5w6fw6q 353 19 of of IN cord-006870-f5w6fw6q 353 20 CPR CPR NNP cord-006870-f5w6fw6q 353 21 among among IN cord-006870-f5w6fw6q 353 22 stroke stroke NN cord-006870-f5w6fw6q 353 23 patients patient NNS cord-006870-f5w6fw6q 353 24 . . . cord-006870-f5w6fw6q 354 1 There there EX cord-006870-f5w6fw6q 354 2 is be VBZ cord-006870-f5w6fw6q 354 3 often often RB cord-006870-f5w6fw6q 354 4 a a DT cord-006870-f5w6fw6q 354 5 tendency tendency NN cord-006870-f5w6fw6q 354 6 to to TO cord-006870-f5w6fw6q 354 7 treat treat VB cord-006870-f5w6fw6q 354 8 patients patient NNS cord-006870-f5w6fw6q 354 9 with with IN cord-006870-f5w6fw6q 354 10 traumatic traumatic JJ cord-006870-f5w6fw6q 354 11 brain brain NN cord-006870-f5w6fw6q 354 12 injury injury NN cord-006870-f5w6fw6q 354 13 ( ( -LRB- cord-006870-f5w6fw6q 354 14 TBI TBI NNP cord-006870-f5w6fw6q 354 15 ) ) -RRB- cord-006870-f5w6fw6q 354 16 and and CC cord-006870-f5w6fw6q 354 17 a a DT cord-006870-f5w6fw6q 354 18 Glasgow Glasgow NNP cord-006870-f5w6fw6q 354 19 Coma Coma NNP cord-006870-f5w6fw6q 354 20 Scale Scale NNP cord-006870-f5w6fw6q 354 21 ( ( -LRB- cord-006870-f5w6fw6q 354 22 GCS GCS NNP cord-006870-f5w6fw6q 354 23 ) ) -RRB- cord-006870-f5w6fw6q 354 24 score score NN cord-006870-f5w6fw6q 354 25 of of IN cord-006870-f5w6fw6q 354 26 3 3 CD cord-006870-f5w6fw6q 354 27 on on IN cord-006870-f5w6fw6q 354 28 presentation presentation NN cord-006870-f5w6fw6q 354 29 less less RBR cord-006870-f5w6fw6q 354 30 aggressively aggressively RB cord-006870-f5w6fw6q 354 31 because because IN cord-006870-f5w6fw6q 354 32 of of IN cord-006870-f5w6fw6q 354 33 low low JJ cord-006870-f5w6fw6q 354 34 expectations expectation NNS cord-006870-f5w6fw6q 354 35 for for IN cord-006870-f5w6fw6q 354 36 a a DT cord-006870-f5w6fw6q 354 37 good good JJ cord-006870-f5w6fw6q 354 38 outcome outcome NN cord-006870-f5w6fw6q 354 39 . . . cord-006870-f5w6fw6q 355 1 Based base VBN cord-006870-f5w6fw6q 355 2 on on IN cord-006870-f5w6fw6q 355 3 the the DT cord-006870-f5w6fw6q 355 4 CRASH crash NN cord-006870-f5w6fw6q 355 5 trial trial NN cord-006870-f5w6fw6q 355 6 database database NN cord-006870-f5w6fw6q 355 7 , , , cord-006870-f5w6fw6q 355 8 a a DT cord-006870-f5w6fw6q 355 9 prognosis prognosis NN cord-006870-f5w6fw6q 355 10 calculator calculator NN cord-006870-f5w6fw6q 355 11 has have VBZ cord-006870-f5w6fw6q 355 12 been be VBN cord-006870-f5w6fw6q 355 13 developed develop VBN cord-006870-f5w6fw6q 355 14 for for IN cord-006870-f5w6fw6q 355 15 the the DT cord-006870-f5w6fw6q 355 16 prediction prediction NN cord-006870-f5w6fw6q 355 17 of of IN cord-006870-f5w6fw6q 355 18 outcome outcome NN cord-006870-f5w6fw6q 355 19 in in IN cord-006870-f5w6fw6q 355 20 TBI TBI NNP cord-006870-f5w6fw6q 355 21 patients patient NNS cord-006870-f5w6fw6q 355 22 . . . cord-006870-f5w6fw6q 356 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 356 2 aim aim NN cord-006870-f5w6fw6q 356 3 was be VBD cord-006870-f5w6fw6q 356 4 to to TO cord-006870-f5w6fw6q 356 5 investigate investigate VB cord-006870-f5w6fw6q 356 6 whether whether IN cord-006870-f5w6fw6q 356 7 the the DT cord-006870-f5w6fw6q 356 8 CRASH crash NN cord-006870-f5w6fw6q 356 9 calculator calculator NN cord-006870-f5w6fw6q 356 10 can can MD cord-006870-f5w6fw6q 356 11 be be VB cord-006870-f5w6fw6q 356 12 used use VBN cord-006870-f5w6fw6q 356 13 for for IN cord-006870-f5w6fw6q 356 14 prognostication prognostication NN cord-006870-f5w6fw6q 356 15 in in IN cord-006870-f5w6fw6q 356 16 patients patient NNS cord-006870-f5w6fw6q 356 17 with with IN cord-006870-f5w6fw6q 356 18 TBI TBI NNP cord-006870-f5w6fw6q 356 19 and and CC cord-006870-f5w6fw6q 356 20 GCS GCS NNP cord-006870-f5w6fw6q 356 21 of of IN cord-006870-f5w6fw6q 356 22 3 3 CD cord-006870-f5w6fw6q 356 23 on on IN cord-006870-f5w6fw6q 356 24 presentation presentation NN cord-006870-f5w6fw6q 356 25 . . . cord-006870-f5w6fw6q 357 1 We -PRON- PRP cord-006870-f5w6fw6q 357 2 performed perform VBD cord-006870-f5w6fw6q 357 3 a a DT cord-006870-f5w6fw6q 357 4 retrospective retrospective JJ cord-006870-f5w6fw6q 357 5 review review NN cord-006870-f5w6fw6q 357 6 of of IN cord-006870-f5w6fw6q 357 7 patients patient NNS cord-006870-f5w6fw6q 357 8 with with IN cord-006870-f5w6fw6q 357 9 TBI TBI NNP cord-006870-f5w6fw6q 357 10 and and CC cord-006870-f5w6fw6q 357 11 a a DT cord-006870-f5w6fw6q 357 12 GCS GCS NNP cord-006870-f5w6fw6q 357 13 score score NN cord-006870-f5w6fw6q 357 14 of of IN cord-006870-f5w6fw6q 357 15 3 3 CD cord-006870-f5w6fw6q 357 16 from from IN cord-006870-f5w6fw6q 357 17 1/12 1/12 CD cord-006870-f5w6fw6q 357 18 to to IN cord-006870-f5w6fw6q 357 19 9/16 9/16 CD cord-006870-f5w6fw6q 357 20 . . . cord-006870-f5w6fw6q 358 1 The the DT cord-006870-f5w6fw6q 358 2 CRASH crash NN cord-006870-f5w6fw6q 358 3 calculator calculator NN cord-006870-f5w6fw6q 358 4 has have VBZ cord-006870-f5w6fw6q 358 5 been be VBN cord-006870-f5w6fw6q 358 6 validated validate VBN cord-006870-f5w6fw6q 358 7 to to TO cord-006870-f5w6fw6q 358 8 estimate estimate VB cord-006870-f5w6fw6q 358 9 mortality mortality NN cord-006870-f5w6fw6q 358 10 at at IN cord-006870-f5w6fw6q 358 11 14 14 CD cord-006870-f5w6fw6q 358 12 days day NNS cord-006870-f5w6fw6q 358 13 and and CC cord-006870-f5w6fw6q 358 14 death death NN cord-006870-f5w6fw6q 358 15 and and CC cord-006870-f5w6fw6q 358 16 severe severe JJ cord-006870-f5w6fw6q 358 17 disability disability NN cord-006870-f5w6fw6q 358 18 at at IN cord-006870-f5w6fw6q 358 19 six six CD cord-006870-f5w6fw6q 358 20 months month NNS cord-006870-f5w6fw6q 358 21 ( ( -LRB- cord-006870-f5w6fw6q 358 22 Glasgow Glasgow NNP cord-006870-f5w6fw6q 358 23 Outcome Outcome NNP cord-006870-f5w6fw6q 358 24 Scale Scale NNP cord-006870-f5w6fw6q 358 25 - - HYPH cord-006870-f5w6fw6q 358 26 GOS GOS NNP cord-006870-f5w6fw6q 358 27 1 1 CD cord-006870-f5w6fw6q 358 28 - - SYM cord-006870-f5w6fw6q 358 29 3 3 CD cord-006870-f5w6fw6q 358 30 ) ) -RRB- cord-006870-f5w6fw6q 358 31 . . . cord-006870-f5w6fw6q 359 1 The the DT cord-006870-f5w6fw6q 359 2 calculator calculator NN cord-006870-f5w6fw6q 359 3 uses use VBZ cord-006870-f5w6fw6q 359 4 country country NN cord-006870-f5w6fw6q 359 5 of of IN cord-006870-f5w6fw6q 359 6 origin origin NN cord-006870-f5w6fw6q 359 7 ( ( -LRB- cord-006870-f5w6fw6q 359 8 USA USA NNP cord-006870-f5w6fw6q 359 9 in in IN cord-006870-f5w6fw6q 359 10 our -PRON- PRP$ cord-006870-f5w6fw6q 359 11 dataset dataset NN cord-006870-f5w6fw6q 359 12 ) ) -RRB- cord-006870-f5w6fw6q 359 13 , , , cord-006870-f5w6fw6q 359 14 Age Age NNP cord-006870-f5w6fw6q 359 15 , , , cord-006870-f5w6fw6q 359 16 GCS GCS NNP cord-006870-f5w6fw6q 359 17 , , , cord-006870-f5w6fw6q 359 18 pupils pupil NNS cord-006870-f5w6fw6q 359 19 reactivity reactivity NN cord-006870-f5w6fw6q 359 20 to to IN cord-006870-f5w6fw6q 359 21 light light NN cord-006870-f5w6fw6q 359 22 , , , cord-006870-f5w6fw6q 359 23 presence presence NN cord-006870-f5w6fw6q 359 24 of of IN cord-006870-f5w6fw6q 359 25 major major JJ cord-006870-f5w6fw6q 359 26 extracranial extracranial JJ cord-006870-f5w6fw6q 359 27 injury injury NN cord-006870-f5w6fw6q 359 28 , , , cord-006870-f5w6fw6q 359 29 and and CC cord-006870-f5w6fw6q 359 30 findings finding NNS cord-006870-f5w6fw6q 359 31 on on IN cord-006870-f5w6fw6q 359 32 CT CT NNP cord-006870-f5w6fw6q 359 33 scan scan NN cord-006870-f5w6fw6q 359 34 of of IN cord-006870-f5w6fw6q 359 35 brain brain NN cord-006870-f5w6fw6q 359 36 ( ( -LRB- cord-006870-f5w6fw6q 359 37 petechial petechial JJ cord-006870-f5w6fw6q 359 38 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 359 39 , , , cord-006870-f5w6fw6q 359 40 Obliteration obliteration NN cord-006870-f5w6fw6q 359 41 of of IN cord-006870-f5w6fw6q 359 42 the the DT cord-006870-f5w6fw6q 359 43 third third JJ cord-006870-f5w6fw6q 359 44 ventricle ventricle NN cord-006870-f5w6fw6q 359 45 or or CC cord-006870-f5w6fw6q 359 46 basal basal NN cord-006870-f5w6fw6q 359 47 cisterns cistern NNS cord-006870-f5w6fw6q 359 48 , , , cord-006870-f5w6fw6q 359 49 Subarachnoid Subarachnoid NNP cord-006870-f5w6fw6q 359 50 bleeding bleed VBG cord-006870-f5w6fw6q 359 51 , , , cord-006870-f5w6fw6q 359 52 Midline Midline NNP cord-006870-f5w6fw6q 359 53 shift shift NN cord-006870-f5w6fw6q 359 54 , , , cord-006870-f5w6fw6q 359 55 and and CC cord-006870-f5w6fw6q 359 56 Non Non NNP cord-006870-f5w6fw6q 359 57 - - JJ cord-006870-f5w6fw6q 359 58 evacuated evacuate VBN cord-006870-f5w6fw6q 359 59 hematoma hematoma NN cord-006870-f5w6fw6q 359 60 ) ) -RRB- cord-006870-f5w6fw6q 359 61 . . . cord-006870-f5w6fw6q 360 1 The the DT cord-006870-f5w6fw6q 360 2 individual individual JJ cord-006870-f5w6fw6q 360 3 prognosis prognosis NN cord-006870-f5w6fw6q 360 4 for for IN cord-006870-f5w6fw6q 360 5 mortality mortality NN cord-006870-f5w6fw6q 360 6 at at IN cord-006870-f5w6fw6q 360 7 14 14 CD cord-006870-f5w6fw6q 360 8 days day NNS cord-006870-f5w6fw6q 360 9 and and CC cord-006870-f5w6fw6q 360 10 unfavourable unfavourable JJ cord-006870-f5w6fw6q 360 11 outcome outcome NN cord-006870-f5w6fw6q 360 12 at at IN cord-006870-f5w6fw6q 360 13 6 6 CD cord-006870-f5w6fw6q 360 14 months month NNS cord-006870-f5w6fw6q 360 15 was be VBD cord-006870-f5w6fw6q 360 16 calculated calculate VBN cord-006870-f5w6fw6q 360 17 and and CC cord-006870-f5w6fw6q 360 18 compared compare VBN cord-006870-f5w6fw6q 360 19 with with IN cord-006870-f5w6fw6q 360 20 the the DT cord-006870-f5w6fw6q 360 21 actual actual JJ cord-006870-f5w6fw6q 360 22 outcomes outcome NNS cord-006870-f5w6fw6q 360 23 . . . cord-006870-f5w6fw6q 361 1 A a DT cord-006870-f5w6fw6q 361 2 total total NN cord-006870-f5w6fw6q 361 3 of of IN cord-006870-f5w6fw6q 361 4 62 62 CD cord-006870-f5w6fw6q 361 5 patients patient NNS cord-006870-f5w6fw6q 361 6 were be VBD cord-006870-f5w6fw6q 361 7 included include VBN cord-006870-f5w6fw6q 361 8 . . . cord-006870-f5w6fw6q 362 1 A a DT cord-006870-f5w6fw6q 362 2 tend tend VBP cord-006870-f5w6fw6q 362 3 toward toward IN cord-006870-f5w6fw6q 362 4 underestimation underestimation NN cord-006870-f5w6fw6q 362 5 of of IN cord-006870-f5w6fw6q 362 6 the the DT cord-006870-f5w6fw6q 362 7 risk risk NN cord-006870-f5w6fw6q 362 8 of of IN cord-006870-f5w6fw6q 362 9 mortality mortality NN cord-006870-f5w6fw6q 362 10 at at IN cord-006870-f5w6fw6q 362 11 14 14 CD cord-006870-f5w6fw6q 362 12 days day NNS cord-006870-f5w6fw6q 362 13 was be VBD cord-006870-f5w6fw6q 362 14 found find VBN cord-006870-f5w6fw6q 362 15 ( ( -LRB- cord-006870-f5w6fw6q 362 16 Estimated estimate VBN cord-006870-f5w6fw6q 362 17 mortality mortality NN cord-006870-f5w6fw6q 362 18 was be VBD cord-006870-f5w6fw6q 362 19 66 66 CD cord-006870-f5w6fw6q 362 20 % % NN cord-006870-f5w6fw6q 362 21 compared compare VBN cord-006870-f5w6fw6q 362 22 to to IN cord-006870-f5w6fw6q 362 23 actual actual JJ cord-006870-f5w6fw6q 362 24 mortality mortality NN cord-006870-f5w6fw6q 362 25 of of IN cord-006870-f5w6fw6q 362 26 81 81 CD cord-006870-f5w6fw6q 362 27 % % NN cord-006870-f5w6fw6q 362 28 ; ; : cord-006870-f5w6fw6q 362 29 Difference difference NN cord-006870-f5w6fw6q 362 30 of of IN cord-006870-f5w6fw6q 362 31 15 15 CD cord-006870-f5w6fw6q 362 32 % % NN cord-006870-f5w6fw6q 362 33 , , , cord-006870-f5w6fw6q 362 34 p p NN cord-006870-f5w6fw6q 362 35 = = SYM cord-006870-f5w6fw6q 362 36 0.05 0.05 CD cord-006870-f5w6fw6q 362 37 ) ) -RRB- cord-006870-f5w6fw6q 362 38 . . . cord-006870-f5w6fw6q 363 1 However however RB cord-006870-f5w6fw6q 363 2 , , , cord-006870-f5w6fw6q 363 3 the the DT cord-006870-f5w6fw6q 363 4 estimation estimation NN cord-006870-f5w6fw6q 363 5 of of IN cord-006870-f5w6fw6q 363 6 outcome outcome NN cord-006870-f5w6fw6q 363 7 at at IN cord-006870-f5w6fw6q 363 8 6 6 CD cord-006870-f5w6fw6q 363 9 months month NNS cord-006870-f5w6fw6q 363 10 was be VBD cord-006870-f5w6fw6q 363 11 accurate accurate JJ cord-006870-f5w6fw6q 363 12 ( ( -LRB- cord-006870-f5w6fw6q 363 13 Estimated estimate VBN cord-006870-f5w6fw6q 363 14 GOS GOS NNP cord-006870-f5w6fw6q 363 15 1 1 CD cord-006870-f5w6fw6q 363 16 - - SYM cord-006870-f5w6fw6q 363 17 3 3 CD cord-006870-f5w6fw6q 363 18 was be VBD cord-006870-f5w6fw6q 363 19 85.5 85.5 CD cord-006870-f5w6fw6q 363 20 % % NN cord-006870-f5w6fw6q 363 21 compared compare VBN cord-006870-f5w6fw6q 363 22 to to IN cord-006870-f5w6fw6q 363 23 actual actual JJ cord-006870-f5w6fw6q 363 24 of of IN cord-006870-f5w6fw6q 363 25 85.5 85.5 CD cord-006870-f5w6fw6q 363 26 % % NN cord-006870-f5w6fw6q 363 27 , , , cord-006870-f5w6fw6q 363 28 p p NN cord-006870-f5w6fw6q 363 29 = = SYM cord-006870-f5w6fw6q 363 30 1.0 1.0 CD cord-006870-f5w6fw6q 363 31 ) ) -RRB- cord-006870-f5w6fw6q 363 32 . . . cord-006870-f5w6fw6q 364 1 The the DT cord-006870-f5w6fw6q 364 2 CRASH crash NN cord-006870-f5w6fw6q 364 3 prognosis prognosis NN cord-006870-f5w6fw6q 364 4 calculator calculator NN cord-006870-f5w6fw6q 364 5 underestimated underestimate VBD cord-006870-f5w6fw6q 364 6 the the DT cord-006870-f5w6fw6q 364 7 risk risk NN cord-006870-f5w6fw6q 364 8 of of IN cord-006870-f5w6fw6q 364 9 mortality mortality NN cord-006870-f5w6fw6q 364 10 , , , cord-006870-f5w6fw6q 364 11 but but CC cord-006870-f5w6fw6q 364 12 accurately accurately RB cord-006870-f5w6fw6q 364 13 predicted predict VBD cord-006870-f5w6fw6q 364 14 unfavourable unfavourable JJ cord-006870-f5w6fw6q 364 15 6 6 CD cord-006870-f5w6fw6q 364 16 month month NN cord-006870-f5w6fw6q 364 17 outcome outcome NN cord-006870-f5w6fw6q 364 18 in in IN cord-006870-f5w6fw6q 364 19 patients patient NNS cord-006870-f5w6fw6q 364 20 with with IN cord-006870-f5w6fw6q 364 21 TBI TBI NNP cord-006870-f5w6fw6q 364 22 and and CC cord-006870-f5w6fw6q 364 23 GCS GCS NNP cord-006870-f5w6fw6q 364 24 of of IN cord-006870-f5w6fw6q 364 25 3 3 CD cord-006870-f5w6fw6q 364 26 on on IN cord-006870-f5w6fw6q 364 27 presentation presentation NN cord-006870-f5w6fw6q 364 28 . . . cord-006870-f5w6fw6q 365 1 Pending pende VBG cord-006870-f5w6fw6q 365 2 larger large JJR cord-006870-f5w6fw6q 365 3 studies study NNS cord-006870-f5w6fw6q 365 4 to to TO cord-006870-f5w6fw6q 365 5 validate validate VB cord-006870-f5w6fw6q 365 6 our -PRON- PRP$ cord-006870-f5w6fw6q 365 7 findings finding NNS cord-006870-f5w6fw6q 365 8 , , , cord-006870-f5w6fw6q 365 9 we -PRON- PRP cord-006870-f5w6fw6q 365 10 believe believe VBP cord-006870-f5w6fw6q 365 11 that that IN cord-006870-f5w6fw6q 365 12 CRASH crash NN cord-006870-f5w6fw6q 365 13 calculator calculator NN cord-006870-f5w6fw6q 365 14 can can MD cord-006870-f5w6fw6q 365 15 only only RB cord-006870-f5w6fw6q 365 16 support support VB cord-006870-f5w6fw6q 365 17 -not -not : cord-006870-f5w6fw6q 365 18 replace replace VB cord-006870-f5w6fw6q 365 19 -clinical -clinical JJ cord-006870-f5w6fw6q 365 20 judgment judgment NN cord-006870-f5w6fw6q 365 21 . . . cord-006870-f5w6fw6q 366 1 There there EX cord-006870-f5w6fw6q 366 2 are be VBP cord-006870-f5w6fw6q 366 3 no no DT cord-006870-f5w6fw6q 366 4 nationally nationally RB cord-006870-f5w6fw6q 366 5 enforced enforce VBN cord-006870-f5w6fw6q 366 6 standards standard NNS cord-006870-f5w6fw6q 366 7 regarding regard VBG cord-006870-f5w6fw6q 366 8 brain brain NN cord-006870-f5w6fw6q 366 9 death death NN cord-006870-f5w6fw6q 366 10 . . . cord-006870-f5w6fw6q 367 1 Few few JJ cord-006870-f5w6fw6q 367 2 data datum NNS cord-006870-f5w6fw6q 367 3 exist exist VBP cord-006870-f5w6fw6q 367 4 on on IN cord-006870-f5w6fw6q 367 5 how how WRB cord-006870-f5w6fw6q 367 6 brain brain NN cord-006870-f5w6fw6q 367 7 death death NN cord-006870-f5w6fw6q 367 8 is be VBZ cord-006870-f5w6fw6q 367 9 determined determine VBN cord-006870-f5w6fw6q 367 10 across across IN cord-006870-f5w6fw6q 367 11 the the DT cord-006870-f5w6fw6q 367 12 U.S. U.S. NNP cord-006870-f5w6fw6q 368 1 We -PRON- PRP cord-006870-f5w6fw6q 368 2 used use VBD cord-006870-f5w6fw6q 368 3 claims claim NNS cord-006870-f5w6fw6q 368 4 data datum NNS cord-006870-f5w6fw6q 368 5 from from IN cord-006870-f5w6fw6q 368 6 2012 2012 CD cord-006870-f5w6fw6q 368 7 - - SYM cord-006870-f5w6fw6q 368 8 2015 2015 CD cord-006870-f5w6fw6q 368 9 from from IN cord-006870-f5w6fw6q 368 10 a a DT cord-006870-f5w6fw6q 368 11 nationally nationally RB cord-006870-f5w6fw6q 368 12 representative representative JJ cord-006870-f5w6fw6q 368 13 5 5 CD cord-006870-f5w6fw6q 368 14 % % NN cord-006870-f5w6fw6q 368 15 sample sample NN cord-006870-f5w6fw6q 368 16 of of IN cord-006870-f5w6fw6q 368 17 Medicare Medicare NNP cord-006870-f5w6fw6q 368 18 defined define VBN cord-006870-f5w6fw6q 368 19 as as IN cord-006870-f5w6fw6q 368 20 ICD-9-CM ICD-9-CM NNP cord-006870-f5w6fw6q 368 21 code code NN cord-006870-f5w6fw6q 368 22 348.82 348.82 CD cord-006870-f5w6fw6q 368 23 . . . cord-006870-f5w6fw6q 369 1 The the DT cord-006870-f5w6fw6q 369 2 primary primary JJ cord-006870-f5w6fw6q 369 3 outcomes outcome NNS cord-006870-f5w6fw6q 369 4 were be VBD cord-006870-f5w6fw6q 369 5 evaluation evaluation NN cord-006870-f5w6fw6q 369 6 by by IN cord-006870-f5w6fw6q 369 7 a a DT cord-006870-f5w6fw6q 369 8 neurologist neurologist NN cord-006870-f5w6fw6q 369 9 or or CC cord-006870-f5w6fw6q 369 10 neurosurgeon neurosurgeon NN cord-006870-f5w6fw6q 369 11 , , , cord-006870-f5w6fw6q 369 12 defined define VBN cord-006870-f5w6fw6q 369 13 as as IN cord-006870-f5w6fw6q 369 14 a a DT cord-006870-f5w6fw6q 369 15 physician physician NN cord-006870-f5w6fw6q 369 16 evaluation evaluation NN cord-006870-f5w6fw6q 369 17 - - HYPH cord-006870-f5w6fw6q 369 18 and and CC cord-006870-f5w6fw6q 369 19 - - HYPH cord-006870-f5w6fw6q 369 20 management management NN cord-006870-f5w6fw6q 369 21 claim claim NN cord-006870-f5w6fw6q 369 22 associated associate VBN cord-006870-f5w6fw6q 369 23 with with IN cord-006870-f5w6fw6q 369 24 the the DT cord-006870-f5w6fw6q 369 25 Medicare Medicare NNP cord-006870-f5w6fw6q 369 26 provider provider NN cord-006870-f5w6fw6q 369 27 specialty specialty NN cord-006870-f5w6fw6q 369 28 codes code NNS cord-006870-f5w6fw6q 369 29 for for IN cord-006870-f5w6fw6q 369 30 neurology neurology NN cord-006870-f5w6fw6q 369 31 or or CC cord-006870-f5w6fw6q 369 32 neurosurgery neurosurgery NNP cord-006870-f5w6fw6q 369 33 , , , cord-006870-f5w6fw6q 369 34 during during IN cord-006870-f5w6fw6q 369 35 the the DT cord-006870-f5w6fw6q 369 36 dates date NNS cord-006870-f5w6fw6q 369 37 of of IN cord-006870-f5w6fw6q 369 38 the the DT cord-006870-f5w6fw6q 369 39 hospitalization hospitalization NN cord-006870-f5w6fw6q 369 40 . . . cord-006870-f5w6fw6q 370 1 CPT CPT NNP cord-006870-f5w6fw6q 370 2 codes code NNS cord-006870-f5w6fw6q 370 3 were be VBD cord-006870-f5w6fw6q 370 4 used use VBN cord-006870-f5w6fw6q 370 5 to to TO cord-006870-f5w6fw6q 370 6 ascertain ascertain VB cord-006870-f5w6fw6q 370 7 ancillary ancillary JJ cord-006870-f5w6fw6q 370 8 testing testing NN cord-006870-f5w6fw6q 370 9 : : : cord-006870-f5w6fw6q 370 10 brain brain NN cord-006870-f5w6fw6q 370 11 radionuclide radionuclide NN cord-006870-f5w6fw6q 370 12 imaging imaging NN cord-006870-f5w6fw6q 370 13 , , , cord-006870-f5w6fw6q 370 14 transcranial transcranial JJ cord-006870-f5w6fw6q 370 15 Doppler Doppler NNP cord-006870-f5w6fw6q 370 16 ultrasound ultrasound NN cord-006870-f5w6fw6q 370 17 , , , cord-006870-f5w6fw6q 370 18 or or CC cord-006870-f5w6fw6q 370 19 electroencephalography electroencephalography NN cord-006870-f5w6fw6q 370 20 for for IN cord-006870-f5w6fw6q 370 21 brain brain NN cord-006870-f5w6fw6q 370 22 death death NN cord-006870-f5w6fw6q 370 23 determination determination NN cord-006870-f5w6fw6q 370 24 . . . cord-006870-f5w6fw6q 371 1 Exact exact JJ cord-006870-f5w6fw6q 371 2 binomial binomial JJ cord-006870-f5w6fw6q 371 3 confidence confidence NN cord-006870-f5w6fw6q 371 4 intervals interval NNS cord-006870-f5w6fw6q 371 5 ( ( -LRB- cord-006870-f5w6fw6q 371 6 CIs CIs NNP cord-006870-f5w6fw6q 371 7 ) ) -RRB- cord-006870-f5w6fw6q 371 8 were be VBD cord-006870-f5w6fw6q 371 9 used use VBN cord-006870-f5w6fw6q 371 10 to to TO cord-006870-f5w6fw6q 371 11 report report VB cord-006870-f5w6fw6q 371 12 proportions proportion NNS cord-006870-f5w6fw6q 371 13 . . . cord-006870-f5w6fw6q 372 1 We -PRON- PRP cord-006870-f5w6fw6q 372 2 identified identify VBD cord-006870-f5w6fw6q 372 3 312 312 CD cord-006870-f5w6fw6q 372 4 patients patient NNS cord-006870-f5w6fw6q 372 5 with with IN cord-006870-f5w6fw6q 372 6 a a DT cord-006870-f5w6fw6q 372 7 brain brain NN cord-006870-f5w6fw6q 372 8 death death NN cord-006870-f5w6fw6q 372 9 diagnosis diagnosis NN cord-006870-f5w6fw6q 372 10 . . . cord-006870-f5w6fw6q 373 1 Common common JJ cord-006870-f5w6fw6q 373 2 associated associate VBD cord-006870-f5w6fw6q 373 3 neurological neurological JJ cord-006870-f5w6fw6q 373 4 diagnoses diagnosis NNS cord-006870-f5w6fw6q 373 5 were be VBD cord-006870-f5w6fw6q 373 6 stroke stroke NN cord-006870-f5w6fw6q 373 7 ( ( -LRB- cord-006870-f5w6fw6q 373 8 122 122 CD cord-006870-f5w6fw6q 373 9 patients patient NNS cord-006870-f5w6fw6q 373 10 ; ; : cord-006870-f5w6fw6q 373 11 39.1 39.1 CD cord-006870-f5w6fw6q 373 12 % % NN cord-006870-f5w6fw6q 373 13 ) ) -RRB- cord-006870-f5w6fw6q 373 14 , , , cord-006870-f5w6fw6q 373 15 cardiac cardiac JJ cord-006870-f5w6fw6q 373 16 arrest arrest NN cord-006870-f5w6fw6q 373 17 ( ( -LRB- cord-006870-f5w6fw6q 373 18 120 120 CD cord-006870-f5w6fw6q 373 19 ; ; : cord-006870-f5w6fw6q 373 20 38.5 38.5 CD cord-006870-f5w6fw6q 373 21 % % NN cord-006870-f5w6fw6q 373 22 ) ) -RRB- cord-006870-f5w6fw6q 373 23 , , , cord-006870-f5w6fw6q 373 24 and and CC cord-006870-f5w6fw6q 373 25 traumatic traumatic JJ cord-006870-f5w6fw6q 373 26 brain brain NN cord-006870-f5w6fw6q 373 27 injury injury NN cord-006870-f5w6fw6q 373 28 ( ( -LRB- cord-006870-f5w6fw6q 373 29 TBI TBI NNP cord-006870-f5w6fw6q 373 30 ) ) -RRB- cord-006870-f5w6fw6q 373 31 ( ( -LRB- cord-006870-f5w6fw6q 373 32 45 45 CD cord-006870-f5w6fw6q 373 33 ; ; : cord-006870-f5w6fw6q 373 34 14.4 14.4 CD cord-006870-f5w6fw6q 373 35 % % NN cord-006870-f5w6fw6q 373 36 ) ) -RRB- cord-006870-f5w6fw6q 373 37 . . . cord-006870-f5w6fw6q 374 1 Head Head NNP cord-006870-f5w6fw6q 374 2 CT CT NNP cord-006870-f5w6fw6q 374 3 or or CC cord-006870-f5w6fw6q 374 4 brain brain NN cord-006870-f5w6fw6q 374 5 MRI MRI NNP cord-006870-f5w6fw6q 374 6 was be VBD cord-006870-f5w6fw6q 374 7 performed perform VBN cord-006870-f5w6fw6q 374 8 in in IN cord-006870-f5w6fw6q 374 9 79.8 79.8 CD cord-006870-f5w6fw6q 374 10 % % NN cord-006870-f5w6fw6q 374 11 ; ; : cord-006870-f5w6fw6q 374 12 this this DT cord-006870-f5w6fw6q 374 13 was be VBD cord-006870-f5w6fw6q 374 14 true true JJ cord-006870-f5w6fw6q 374 15 of of IN cord-006870-f5w6fw6q 374 16 91.6 91.6 CD cord-006870-f5w6fw6q 374 17 % % NN cord-006870-f5w6fw6q 374 18 of of IN cord-006870-f5w6fw6q 374 19 cases case NNS cord-006870-f5w6fw6q 374 20 of of IN cord-006870-f5w6fw6q 374 21 stroke stroke NN cord-006870-f5w6fw6q 374 22 or or CC cord-006870-f5w6fw6q 374 23 TBI TBI NNP cord-006870-f5w6fw6q 374 24 versus versus IN cord-006870-f5w6fw6q 374 25 68.3 68.3 CD cord-006870-f5w6fw6q 374 26 % % NN cord-006870-f5w6fw6q 374 27 of of IN cord-006870-f5w6fw6q 374 28 cardiac cardiac JJ cord-006870-f5w6fw6q 374 29 arrests arrest NNS cord-006870-f5w6fw6q 374 30 . . . cord-006870-f5w6fw6q 375 1 Neurologists neurologist NNS cord-006870-f5w6fw6q 375 2 were be VBD cord-006870-f5w6fw6q 375 3 involved involve VBN cord-006870-f5w6fw6q 375 4 in in IN cord-006870-f5w6fw6q 375 5 the the DT cord-006870-f5w6fw6q 375 6 care care NN cord-006870-f5w6fw6q 375 7 of of IN cord-006870-f5w6fw6q 375 8 137 137 CD cord-006870-f5w6fw6q 375 9 patients patient NNS cord-006870-f5w6fw6q 375 10 ( ( -LRB- cord-006870-f5w6fw6q 375 11 43.9 43.9 CD cord-006870-f5w6fw6q 375 12 % % NN cord-006870-f5w6fw6q 375 13 ; ; : cord-006870-f5w6fw6q 375 14 95 95 CD cord-006870-f5w6fw6q 375 15 % % NN cord-006870-f5w6fw6q 375 16 CI CI NNP cord-006870-f5w6fw6q 375 17 , , , cord-006870-f5w6fw6q 375 18 38.3 38.3 CD cord-006870-f5w6fw6q 375 19 - - HYPH cord-006870-f5w6fw6q 375 20 49.6 49.6 CD cord-006870-f5w6fw6q 375 21 % % NN cord-006870-f5w6fw6q 375 22 ) ) -RRB- cord-006870-f5w6fw6q 375 23 . . . cord-006870-f5w6fw6q 376 1 They -PRON- PRP cord-006870-f5w6fw6q 376 2 were be VBD cord-006870-f5w6fw6q 376 3 more more RBR cord-006870-f5w6fw6q 376 4 commonly commonly RB cord-006870-f5w6fw6q 376 5 involved involve VBN cord-006870-f5w6fw6q 376 6 in in IN cord-006870-f5w6fw6q 376 7 the the DT cord-006870-f5w6fw6q 376 8 care care NN cord-006870-f5w6fw6q 376 9 of of IN cord-006870-f5w6fw6q 376 10 stroke stroke NN cord-006870-f5w6fw6q 376 11 ( ( -LRB- cord-006870-f5w6fw6q 376 12 50.8 50.8 CD cord-006870-f5w6fw6q 376 13 % % NN cord-006870-f5w6fw6q 376 14 ) ) -RRB- cord-006870-f5w6fw6q 376 15 or or CC cord-006870-f5w6fw6q 376 16 cardiac cardiac JJ cord-006870-f5w6fw6q 376 17 arrest arrest NN cord-006870-f5w6fw6q 376 18 ( ( -LRB- cord-006870-f5w6fw6q 376 19 55.0 55.0 CD cord-006870-f5w6fw6q 376 20 % % NN cord-006870-f5w6fw6q 376 21 ) ) -RRB- cord-006870-f5w6fw6q 376 22 than than IN cord-006870-f5w6fw6q 376 23 TBI TBI NNP cord-006870-f5w6fw6q 376 24 ( ( -LRB- cord-006870-f5w6fw6q 376 25 6.7 6.7 CD cord-006870-f5w6fw6q 376 26 % % NN cord-006870-f5w6fw6q 376 27 ) ) -RRB- cord-006870-f5w6fw6q 376 28 or or CC cord-006870-f5w6fw6q 376 29 other other JJ cord-006870-f5w6fw6q 376 30 conditions condition NNS cord-006870-f5w6fw6q 376 31 ( ( -LRB- cord-006870-f5w6fw6q 376 32 24.0 24.0 CD cord-006870-f5w6fw6q 376 33 % % NN cord-006870-f5w6fw6q 376 34 ) ) -RRB- cord-006870-f5w6fw6q 376 35 . . . cord-006870-f5w6fw6q 377 1 Neurosurgeons neurosurgeon NNS cord-006870-f5w6fw6q 377 2 were be VBD cord-006870-f5w6fw6q 377 3 involved involve VBN cord-006870-f5w6fw6q 377 4 in in IN cord-006870-f5w6fw6q 377 5 98 98 CD cord-006870-f5w6fw6q 377 6 cases case NNS cord-006870-f5w6fw6q 377 7 ( ( -LRB- cord-006870-f5w6fw6q 377 8 31.4 31.4 CD cord-006870-f5w6fw6q 377 9 % % NN cord-006870-f5w6fw6q 377 10 ; ; : cord-006870-f5w6fw6q 377 11 95 95 CD cord-006870-f5w6fw6q 377 12 % % NN cord-006870-f5w6fw6q 377 13 CI CI NNP cord-006870-f5w6fw6q 377 14 , , , cord-006870-f5w6fw6q 377 15 26.3 26.3 CD cord-006870-f5w6fw6q 377 16 - - HYPH cord-006870-f5w6fw6q 377 17 36.9 36.9 CD cord-006870-f5w6fw6q 377 18 % % NN cord-006870-f5w6fw6q 377 19 ) ) -RRB- cord-006870-f5w6fw6q 377 20 , , , cord-006870-f5w6fw6q 377 21 mostly mostly RB cord-006870-f5w6fw6q 377 22 after after IN cord-006870-f5w6fw6q 377 23 TBI TBI NNP cord-006870-f5w6fw6q 377 24 or or CC cord-006870-f5w6fw6q 377 25 stroke stroke NN cord-006870-f5w6fw6q 377 26 . . . cord-006870-f5w6fw6q 378 1 Two two CD cord-006870-f5w6fw6q 378 2 hundred hundred CD cord-006870-f5w6fw6q 378 3 patients patient NNS cord-006870-f5w6fw6q 378 4 ( ( -LRB- cord-006870-f5w6fw6q 378 5 64.1 64.1 CD cord-006870-f5w6fw6q 378 6 % % NN cord-006870-f5w6fw6q 378 7 ; ; : cord-006870-f5w6fw6q 378 8 95 95 CD cord-006870-f5w6fw6q 378 9 % % NN cord-006870-f5w6fw6q 378 10 CI CI NNP cord-006870-f5w6fw6q 378 11 , , , cord-006870-f5w6fw6q 378 12 58.5 58.5 CD cord-006870-f5w6fw6q 378 13 - - HYPH cord-006870-f5w6fw6q 378 14 69.4 69.4 CD cord-006870-f5w6fw6q 378 15 % % NN cord-006870-f5w6fw6q 378 16 ) ) -RRB- cord-006870-f5w6fw6q 378 17 were be VBD cord-006870-f5w6fw6q 378 18 seen see VBN cord-006870-f5w6fw6q 378 19 by by IN cord-006870-f5w6fw6q 378 20 a a DT cord-006870-f5w6fw6q 378 21 neurologist neurologist NN cord-006870-f5w6fw6q 378 22 or or CC cord-006870-f5w6fw6q 378 23 neurosurgeon neurosurgeon NN cord-006870-f5w6fw6q 378 24 . . . cord-006870-f5w6fw6q 379 1 Twenty twenty CD cord-006870-f5w6fw6q 379 2 - - HYPH cord-006870-f5w6fw6q 379 3 nine nine CD cord-006870-f5w6fw6q 379 4 patients patient NNS cord-006870-f5w6fw6q 379 5 ( ( -LRB- cord-006870-f5w6fw6q 379 6 9.3 9.3 CD cord-006870-f5w6fw6q 379 7 % % NN cord-006870-f5w6fw6q 379 8 ; ; : cord-006870-f5w6fw6q 379 9 95 95 CD cord-006870-f5w6fw6q 379 10 % % NN cord-006870-f5w6fw6q 379 11 CI CI NNP cord-006870-f5w6fw6q 379 12 , , , cord-006870-f5w6fw6q 379 13 6.3 6.3 CD cord-006870-f5w6fw6q 379 14 - - SYM cord-006870-f5w6fw6q 379 15 13.1 13.1 CD cord-006870-f5w6fw6q 379 16 % % NN cord-006870-f5w6fw6q 379 17 ) ) -RRB- cord-006870-f5w6fw6q 379 18 underwent undergo VBD cord-006870-f5w6fw6q 379 19 any any DT cord-006870-f5w6fw6q 379 20 ancillary ancillary JJ cord-006870-f5w6fw6q 379 21 testing testing NN cord-006870-f5w6fw6q 379 22 . . . cord-006870-f5w6fw6q 380 1 Two two CD cord-006870-f5w6fw6q 380 2 hundred hundred CD cord-006870-f5w6fw6q 380 3 and and CC cord-006870-f5w6fw6q 380 4 nine nine CD cord-006870-f5w6fw6q 380 5 patients patient NNS cord-006870-f5w6fw6q 380 6 ( ( -LRB- cord-006870-f5w6fw6q 380 7 67.0 67.0 CD cord-006870-f5w6fw6q 380 8 % % NN cord-006870-f5w6fw6q 380 9 ; ; : cord-006870-f5w6fw6q 380 10 95 95 CD cord-006870-f5w6fw6q 380 11 % % NN cord-006870-f5w6fw6q 380 12 CI ci NN cord-006870-f5w6fw6q 380 13 , , , cord-006870-f5w6fw6q 380 14 61.5 61.5 CD cord-006870-f5w6fw6q 380 15 - - HYPH cord-006870-f5w6fw6q 380 16 72.2 72.2 CD cord-006870-f5w6fw6q 380 17 % % NN cord-006870-f5w6fw6q 380 18 ) ) -RRB- cord-006870-f5w6fw6q 380 19 were be VBD cord-006870-f5w6fw6q 380 20 seen see VBN cord-006870-f5w6fw6q 380 21 by by IN cord-006870-f5w6fw6q 380 22 a a DT cord-006870-f5w6fw6q 380 23 neurologist neurologist NN cord-006870-f5w6fw6q 380 24 or or CC cord-006870-f5w6fw6q 380 25 neurosurgeon neurosurgeon NN cord-006870-f5w6fw6q 380 26 or or CC cord-006870-f5w6fw6q 380 27 underwent undergo VBD cord-006870-f5w6fw6q 380 28 ancillary ancillary JJ cord-006870-f5w6fw6q 380 29 testing testing NN cord-006870-f5w6fw6q 380 30 . . . cord-006870-f5w6fw6q 381 1 In in IN cord-006870-f5w6fw6q 381 2 a a DT cord-006870-f5w6fw6q 381 3 nationally nationally RB cord-006870-f5w6fw6q 381 4 representative representative JJ cord-006870-f5w6fw6q 381 5 cohort cohort NN cord-006870-f5w6fw6q 381 6 of of IN cord-006870-f5w6fw6q 381 7 elderly elderly JJ cord-006870-f5w6fw6q 381 8 patients patient NNS cord-006870-f5w6fw6q 381 9 , , , cord-006870-f5w6fw6q 381 10 one one CD cord-006870-f5w6fw6q 381 11 - - HYPH cord-006870-f5w6fw6q 381 12 third third NN cord-006870-f5w6fw6q 381 13 of of IN cord-006870-f5w6fw6q 381 14 patients patient NNS cord-006870-f5w6fw6q 381 15 with with IN cord-006870-f5w6fw6q 381 16 a a DT cord-006870-f5w6fw6q 381 17 brain brain NN cord-006870-f5w6fw6q 381 18 death death NN cord-006870-f5w6fw6q 381 19 diagnosis diagnosis NN cord-006870-f5w6fw6q 381 20 were be VBD cord-006870-f5w6fw6q 381 21 not not RB cord-006870-f5w6fw6q 381 22 evaluated evaluate VBN cord-006870-f5w6fw6q 381 23 by by IN cord-006870-f5w6fw6q 381 24 a a DT cord-006870-f5w6fw6q 381 25 neurologist neurologist NN cord-006870-f5w6fw6q 381 26 or or CC cord-006870-f5w6fw6q 381 27 neurosurgeon neurosurgeon NN cord-006870-f5w6fw6q 381 28 or or CC cord-006870-f5w6fw6q 381 29 by by IN cord-006870-f5w6fw6q 381 30 using use VBG cord-006870-f5w6fw6q 381 31 ancillary ancillary JJ cord-006870-f5w6fw6q 381 32 tests test NNS cord-006870-f5w6fw6q 381 33 . . . cord-006870-f5w6fw6q 382 1 Traumatic traumatic JJ cord-006870-f5w6fw6q 382 2 brain brain NN cord-006870-f5w6fw6q 382 3 injury injury NN cord-006870-f5w6fw6q 382 4 ( ( -LRB- cord-006870-f5w6fw6q 382 5 TBI TBI NNP cord-006870-f5w6fw6q 382 6 ) ) -RRB- cord-006870-f5w6fw6q 382 7 is be VBZ cord-006870-f5w6fw6q 382 8 a a DT cord-006870-f5w6fw6q 382 9 major major JJ cord-006870-f5w6fw6q 382 10 cause cause NN cord-006870-f5w6fw6q 382 11 of of IN cord-006870-f5w6fw6q 382 12 death death NN cord-006870-f5w6fw6q 382 13 and and CC cord-006870-f5w6fw6q 382 14 disability disability NN cord-006870-f5w6fw6q 382 15 in in IN cord-006870-f5w6fw6q 382 16 the the DT cord-006870-f5w6fw6q 382 17 US US NNP cord-006870-f5w6fw6q 382 18 . . . cord-006870-f5w6fw6q 383 1 Recent recent JJ cord-006870-f5w6fw6q 383 2 advances advance NNS cord-006870-f5w6fw6q 383 3 in in IN cord-006870-f5w6fw6q 383 4 3D 3d JJ cord-006870-f5w6fw6q 383 5 illustration illustration NN cord-006870-f5w6fw6q 383 6 ( ( -LRB- cord-006870-f5w6fw6q 383 7 3DI 3DI NNP cord-006870-f5w6fw6q 383 8 ) ) -RRB- cord-006870-f5w6fw6q 383 9 can can MD cord-006870-f5w6fw6q 383 10 precisely precisely RB cord-006870-f5w6fw6q 383 11 quantify quantify VB cord-006870-f5w6fw6q 383 12 intracranial intracranial JJ cord-006870-f5w6fw6q 383 13 pathology pathology NN cord-006870-f5w6fw6q 383 14 on on IN cord-006870-f5w6fw6q 383 15 computed compute VBN cord-006870-f5w6fw6q 383 16 tomography tomography NN cord-006870-f5w6fw6q 383 17 ( ( -LRB- cord-006870-f5w6fw6q 383 18 CT CT NNP cord-006870-f5w6fw6q 383 19 ) ) -RRB- cord-006870-f5w6fw6q 383 20 . . . cord-006870-f5w6fw6q 384 1 The the DT cord-006870-f5w6fw6q 384 2 current current JJ cord-006870-f5w6fw6q 384 3 standard standard NN cord-006870-f5w6fw6q 384 4 of of IN cord-006870-f5w6fw6q 384 5 measurement measurement NN cord-006870-f5w6fw6q 384 6 , , , cord-006870-f5w6fw6q 384 7 ABC/2 ABC/2 NNP cord-006870-f5w6fw6q 384 8 , , , cord-006870-f5w6fw6q 384 9 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 384 10 variability variability NN cord-006870-f5w6fw6q 384 11 in in IN cord-006870-f5w6fw6q 384 12 precision precision NN cord-006870-f5w6fw6q 384 13 with with IN cord-006870-f5w6fw6q 384 14 bleed bleed NN cord-006870-f5w6fw6q 384 15 phenotype phenotype NN cord-006870-f5w6fw6q 384 16 . . . cord-006870-f5w6fw6q 385 1 The the DT cord-006870-f5w6fw6q 385 2 aim aim NN cord-006870-f5w6fw6q 385 3 of of IN cord-006870-f5w6fw6q 385 4 this this DT cord-006870-f5w6fw6q 385 5 project project NN cord-006870-f5w6fw6q 385 6 is be VBZ cord-006870-f5w6fw6q 385 7 to to TO cord-006870-f5w6fw6q 385 8 assess assess VB cord-006870-f5w6fw6q 385 9 accuracy accuracy NN cord-006870-f5w6fw6q 385 10 automated automate VBN cord-006870-f5w6fw6q 385 11 3DI 3di CD cord-006870-f5w6fw6q 385 12 and and CC cord-006870-f5w6fw6q 385 13 compare compare VB cord-006870-f5w6fw6q 385 14 it -PRON- PRP cord-006870-f5w6fw6q 385 15 to to IN cord-006870-f5w6fw6q 385 16 standard standard JJ cord-006870-f5w6fw6q 385 17 ABC/2 ABC/2 NNP cord-006870-f5w6fw6q 385 18 measurements measurement NNS cord-006870-f5w6fw6q 385 19 . . . cord-006870-f5w6fw6q 386 1 Baseline baseline JJ cord-006870-f5w6fw6q 386 2 CT CT NNP cord-006870-f5w6fw6q 386 3 scans scan NNS cord-006870-f5w6fw6q 386 4 collected collect VBN cord-006870-f5w6fw6q 386 5 during during IN cord-006870-f5w6fw6q 386 6 the the DT cord-006870-f5w6fw6q 386 7 ProTECTIII ProTECTIII NNP cord-006870-f5w6fw6q 386 8 multicenter multicenter JJ cord-006870-f5w6fw6q 386 9 clinical clinical JJ cord-006870-f5w6fw6q 386 10 trial trial NN cord-006870-f5w6fw6q 386 11 ( ( -LRB- cord-006870-f5w6fw6q 386 12 n=881 n=881 NNP cord-006870-f5w6fw6q 386 13 ) ) -RRB- cord-006870-f5w6fw6q 386 14 were be VBD cord-006870-f5w6fw6q 386 15 retrospectively retrospectively RB cord-006870-f5w6fw6q 386 16 reviewed review VBN cord-006870-f5w6fw6q 386 17 by by IN cord-006870-f5w6fw6q 386 18 a a DT cord-006870-f5w6fw6q 386 19 central central JJ cord-006870-f5w6fw6q 386 20 neuroradiologist neuroradiologist NN cord-006870-f5w6fw6q 386 21 . . . cord-006870-f5w6fw6q 387 1 Subdural subdural JJ cord-006870-f5w6fw6q 387 2 and and CC cord-006870-f5w6fw6q 387 3 epidural epidural NN cord-006870-f5w6fw6q 387 4 hematomas hematoma NNS cord-006870-f5w6fw6q 387 5 were be VBD cord-006870-f5w6fw6q 387 6 identified identify VBN cord-006870-f5w6fw6q 387 7 ( ( -LRB- cord-006870-f5w6fw6q 387 8 n260 n260 NNP cord-006870-f5w6fw6q 387 9 ) ) -RRB- cord-006870-f5w6fw6q 387 10 . . . cord-006870-f5w6fw6q 388 1 The the DT cord-006870-f5w6fw6q 388 2 radiologist radiologist NN cord-006870-f5w6fw6q 388 3 calculated calculate VBN cord-006870-f5w6fw6q 388 4 ABC/2 ABC/2 NNP cord-006870-f5w6fw6q 388 5 score score NN cord-006870-f5w6fw6q 388 6 using use VBG cord-006870-f5w6fw6q 388 7 OsiriX osirix NN cord-006870-f5w6fw6q 388 8 ( ( -LRB- cord-006870-f5w6fw6q 388 9 Mac Mac NNP cord-006870-f5w6fw6q 388 10 ) ) -RRB- cord-006870-f5w6fw6q 388 11 and and CC cord-006870-f5w6fw6q 388 12 RadiAnt RadiAnt NNP cord-006870-f5w6fw6q 388 13 ( ( -LRB- cord-006870-f5w6fw6q 388 14 PC pc NN cord-006870-f5w6fw6q 388 15 ) ) -RRB- cord-006870-f5w6fw6q 388 16 workstations workstation NNS cord-006870-f5w6fw6q 388 17 . . . cord-006870-f5w6fw6q 389 1 In in IN cord-006870-f5w6fw6q 389 2 a a DT cord-006870-f5w6fw6q 389 3 blinded blinded JJ cord-006870-f5w6fw6q 389 4 fashion fashion NN cord-006870-f5w6fw6q 389 5 , , , cord-006870-f5w6fw6q 389 6 research research NN cord-006870-f5w6fw6q 389 7 assistants assistant NNS cord-006870-f5w6fw6q 389 8 concurrently concurrently RB cord-006870-f5w6fw6q 389 9 generated generate VBD cord-006870-f5w6fw6q 389 10 3DI 3di CD cord-006870-f5w6fw6q 389 11 using use VBG cord-006870-f5w6fw6q 389 12 the the DT cord-006870-f5w6fw6q 389 13 following follow VBG cord-006870-f5w6fw6q 389 14 methods method NNS cord-006870-f5w6fw6q 389 15 : : : cord-006870-f5w6fw6q 389 16 DICOM DICOM NNP cord-006870-f5w6fw6q 389 17 data datum NNS cord-006870-f5w6fw6q 389 18 were be VBD cord-006870-f5w6fw6q 389 19 resampled resample VBN cord-006870-f5w6fw6q 389 20 to to IN cord-006870-f5w6fw6q 389 21 1.5 1.5 CD cord-006870-f5w6fw6q 389 22 mm mm NN cord-006870-f5w6fw6q 389 23 thickness thickness NN cord-006870-f5w6fw6q 389 24 slices slice NNS cord-006870-f5w6fw6q 389 25 and and CC cord-006870-f5w6fw6q 389 26 symmetrized symmetrize VBN cord-006870-f5w6fw6q 389 27 using use VBG cord-006870-f5w6fw6q 389 28 image image NN cord-006870-f5w6fw6q 389 29 analysis analysis NN cord-006870-f5w6fw6q 389 30 software software NN cord-006870-f5w6fw6q 389 31 ( ( -LRB- cord-006870-f5w6fw6q 389 32 Aquarius Aquarius NNP cord-006870-f5w6fw6q 389 33 TeraRecon TeraRecon NNP cord-006870-f5w6fw6q 389 34 Inc Inc NNP cord-006870-f5w6fw6q 389 35 , , , cord-006870-f5w6fw6q 389 36 2012 2012 CD cord-006870-f5w6fw6q 389 37 ) ) -RRB- cord-006870-f5w6fw6q 389 38 . . . cord-006870-f5w6fw6q 390 1 Lesions lesion NNS cord-006870-f5w6fw6q 390 2 were be VBD cord-006870-f5w6fw6q 390 3 then then RB cord-006870-f5w6fw6q 390 4 compiled compile VBN cord-006870-f5w6fw6q 390 5 into into IN cord-006870-f5w6fw6q 390 6 single single JJ cord-006870-f5w6fw6q 390 7 volumetric volumetric JJ cord-006870-f5w6fw6q 390 8 regions region NNS cord-006870-f5w6fw6q 390 9 of of IN cord-006870-f5w6fw6q 390 10 interest interest NN cord-006870-f5w6fw6q 390 11 ( ( -LRB- cord-006870-f5w6fw6q 390 12 3D 3D NNP cord-006870-f5w6fw6q 390 13 Slicer Slicer NNP cord-006870-f5w6fw6q 390 14 v4.5 v4.5 NN cord-006870-f5w6fw6q 390 15 , , , cord-006870-f5w6fw6q 390 16 2015 2015 CD cord-006870-f5w6fw6q 390 17 ) ) -RRB- cord-006870-f5w6fw6q 390 18 . . . cord-006870-f5w6fw6q 391 1 Hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 391 2 were be VBD cord-006870-f5w6fw6q 391 3 divided divide VBN cord-006870-f5w6fw6q 391 4 into into IN cord-006870-f5w6fw6q 391 5 two two CD cord-006870-f5w6fw6q 391 6 groups group NNS cord-006870-f5w6fw6q 391 7 for for IN cord-006870-f5w6fw6q 391 8 analysis analysis NN cord-006870-f5w6fw6q 391 9 : : : cord-006870-f5w6fw6q 392 1 Group group NN cord-006870-f5w6fw6q 392 2 1 1 CD cord-006870-f5w6fw6q 392 3 . . . cord-006870-f5w6fw6q 393 1 volume volume NN cord-006870-f5w6fw6q 393 2 of of IN cord-006870-f5w6fw6q 393 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 393 4 Bland Bland NNP cord-006870-f5w6fw6q 393 5 - - HYPH cord-006870-f5w6fw6q 393 6 Altman Altman NNP cord-006870-f5w6fw6q 393 7 analysis analysis NN cord-006870-f5w6fw6q 393 8 . . . cord-006870-f5w6fw6q 394 1 This this DT cord-006870-f5w6fw6q 394 2 study study NN cord-006870-f5w6fw6q 394 3 was be VBD cord-006870-f5w6fw6q 394 4 IRB IRB NNP cord-006870-f5w6fw6q 394 5 approved approve VBN cord-006870-f5w6fw6q 394 6 . . . cord-006870-f5w6fw6q 395 1 There there EX cord-006870-f5w6fw6q 395 2 is be VBZ cord-006870-f5w6fw6q 395 3 a a DT cord-006870-f5w6fw6q 395 4 significant significant JJ cord-006870-f5w6fw6q 395 5 difference difference NN cord-006870-f5w6fw6q 395 6 between between IN cord-006870-f5w6fw6q 395 7 the the DT cord-006870-f5w6fw6q 395 8 results result NNS cord-006870-f5w6fw6q 395 9 of of IN cord-006870-f5w6fw6q 395 10 the the DT cord-006870-f5w6fw6q 395 11 3DI 3DI NNP cord-006870-f5w6fw6q 395 12 and and CC cord-006870-f5w6fw6q 395 13 ABC/2 ABC/2 NNP cord-006870-f5w6fw6q 395 14 methods method NNS cord-006870-f5w6fw6q 395 15 . . . cord-006870-f5w6fw6q 396 1 In in IN cord-006870-f5w6fw6q 396 2 Group Group NNP cord-006870-f5w6fw6q 396 3 1 1 CD cord-006870-f5w6fw6q 396 4 . . . cord-006870-f5w6fw6q 397 1 the the DT cord-006870-f5w6fw6q 397 2 estimated estimate VBN cord-006870-f5w6fw6q 397 3 relative relative JJ cord-006870-f5w6fw6q 397 4 bias bias NN cord-006870-f5w6fw6q 397 5 between between IN cord-006870-f5w6fw6q 397 6 the the DT cord-006870-f5w6fw6q 397 7 two two CD cord-006870-f5w6fw6q 397 8 measurements measurement NNS cord-006870-f5w6fw6q 397 9 ( ( -LRB- cord-006870-f5w6fw6q 397 10 after after IN cord-006870-f5w6fw6q 397 11 transformation transformation NN cord-006870-f5w6fw6q 397 12 ) ) -RRB- cord-006870-f5w6fw6q 397 13 is be VBZ cord-006870-f5w6fw6q 397 14 0.17 0.17 CD cord-006870-f5w6fw6q 397 15 ( ( -LRB- cord-006870-f5w6fw6q 397 16 SD SD NNP cord-006870-f5w6fw6q 397 17 1.16 1.16 CD cord-006870-f5w6fw6q 397 18 ; ; : cord-006870-f5w6fw6q 397 19 pvalue pvalue NNP cord-006870-f5w6fw6q 397 20 0.044 0.044 CD cord-006870-f5w6fw6q 397 21 ; ; : cord-006870-f5w6fw6q 397 22 95 95 CD cord-006870-f5w6fw6q 397 23 % % NN cord-006870-f5w6fw6q 397 24 CI CI NNP cord-006870-f5w6fw6q 397 25 0.005 0.005 CD cord-006870-f5w6fw6q 397 26 , , , cord-006870-f5w6fw6q 397 27 0.333 0.333 CD cord-006870-f5w6fw6q 397 28 ) ) -RRB- cord-006870-f5w6fw6q 397 29 . . . cord-006870-f5w6fw6q 398 1 In in IN cord-006870-f5w6fw6q 398 2 Group Group NNP cord-006870-f5w6fw6q 398 3 2 2 CD cord-006870-f5w6fw6q 398 4 , , , cord-006870-f5w6fw6q 398 5 the the DT cord-006870-f5w6fw6q 398 6 relative relative JJ cord-006870-f5w6fw6q 398 7 bias bias NN cord-006870-f5w6fw6q 398 8 is be VBZ cord-006870-f5w6fw6q 398 9 -0.712 -0.712 NNP cord-006870-f5w6fw6q 398 10 , , , cord-006870-f5w6fw6q 398 11 SD SD NNP cord-006870-f5w6fw6q 398 12 1.22 1.22 CD cord-006870-f5w6fw6q 398 13 , , , cord-006870-f5w6fw6q 398 14 pvalue pvalue NNP cord-006870-f5w6fw6q 398 15 < < NNP cord-006870-f5w6fw6q 398 16 0.0001 0.0001 CD cord-006870-f5w6fw6q 398 17 , , , cord-006870-f5w6fw6q 398 18 95 95 CD cord-006870-f5w6fw6q 398 19 % % NN cord-006870-f5w6fw6q 398 20 CI ci NN cord-006870-f5w6fw6q 399 1 ( ( -LRB- cord-006870-f5w6fw6q 399 2 -1.013 -1.013 NNP cord-006870-f5w6fw6q 399 3 , , , cord-006870-f5w6fw6q 399 4 -0.410 -0.410 NNP cord-006870-f5w6fw6q 399 5 ) ) -RRB- cord-006870-f5w6fw6q 399 6 . . . cord-006870-f5w6fw6q 400 1 The the DT cord-006870-f5w6fw6q 400 2 3DI 3di CD cord-006870-f5w6fw6q 400 3 method method NN cord-006870-f5w6fw6q 400 4 calculates calculate VBZ cord-006870-f5w6fw6q 400 5 detailed detailed JJ cord-006870-f5w6fw6q 400 6 surface surface NN cord-006870-f5w6fw6q 400 7 area area NN cord-006870-f5w6fw6q 400 8 measurements measurement NNS cord-006870-f5w6fw6q 400 9 in in IN cord-006870-f5w6fw6q 400 10 large large JJ cord-006870-f5w6fw6q 400 11 and and CC cord-006870-f5w6fw6q 400 12 small small JJ cord-006870-f5w6fw6q 400 13 volume volume NN cord-006870-f5w6fw6q 400 14 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 400 15 , , , cord-006870-f5w6fw6q 400 16 while while IN cord-006870-f5w6fw6q 400 17 ABC/2 ABC/2 NNP cord-006870-f5w6fw6q 400 18 averages average VBZ cord-006870-f5w6fw6q 400 19 cross cross JJ cord-006870-f5w6fw6q 400 20 - - JJ cord-006870-f5w6fw6q 400 21 sectional sectional JJ cord-006870-f5w6fw6q 400 22 area area NN cord-006870-f5w6fw6q 400 23 . . . cord-006870-f5w6fw6q 401 1 The the DT cord-006870-f5w6fw6q 401 2 ABC/2 ABC/2 NNP cord-006870-f5w6fw6q 401 3 estimates estimate NNS cord-006870-f5w6fw6q 401 4 vary vary VBP cord-006870-f5w6fw6q 401 5 by by IN cord-006870-f5w6fw6q 401 6 bleed bleed NN cord-006870-f5w6fw6q 401 7 phenotype phenotype NN cord-006870-f5w6fw6q 401 8 and and CC cord-006870-f5w6fw6q 401 9 offer offer VBP cord-006870-f5w6fw6q 401 10 less less JJR cord-006870-f5w6fw6q 401 11 topographical topographical JJ cord-006870-f5w6fw6q 401 12 precision precision NN cord-006870-f5w6fw6q 401 13 than than IN cord-006870-f5w6fw6q 401 14 3DI 3DI NNP cord-006870-f5w6fw6q 401 15 . . . cord-006870-f5w6fw6q 402 1 This this DT cord-006870-f5w6fw6q 402 2 is be VBZ cord-006870-f5w6fw6q 402 3 particularly particularly RB cord-006870-f5w6fw6q 402 4 true true JJ cord-006870-f5w6fw6q 402 5 in in IN cord-006870-f5w6fw6q 402 6 extra extra JJ cord-006870-f5w6fw6q 402 7 - - JJ cord-006870-f5w6fw6q 402 8 axial axial JJ cord-006870-f5w6fw6q 402 9 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 402 10 , , , cord-006870-f5w6fw6q 402 11 which which WDT cord-006870-f5w6fw6q 402 12 are be VBP cord-006870-f5w6fw6q 402 13 Numerous numerous JJ cord-006870-f5w6fw6q 402 14 studies study NNS cord-006870-f5w6fw6q 402 15 have have VBP cord-006870-f5w6fw6q 402 16 shown show VBN cord-006870-f5w6fw6q 402 17 a a DT cord-006870-f5w6fw6q 402 18 significant significant JJ cord-006870-f5w6fw6q 402 19 association association NN cord-006870-f5w6fw6q 402 20 between between IN cord-006870-f5w6fw6q 402 21 hypotension hypotension NN cord-006870-f5w6fw6q 402 22 and and CC cord-006870-f5w6fw6q 402 23 poor poor JJ cord-006870-f5w6fw6q 402 24 outcome outcome NN cord-006870-f5w6fw6q 402 25 in in IN cord-006870-f5w6fw6q 402 26 patients patient NNS cord-006870-f5w6fw6q 402 27 with with IN cord-006870-f5w6fw6q 402 28 head head NN cord-006870-f5w6fw6q 402 29 injuries injury NNS cord-006870-f5w6fw6q 402 30 . . . cord-006870-f5w6fw6q 403 1 Prior prior JJ cord-006870-f5w6fw6q 403 2 investigations investigation NNS cord-006870-f5w6fw6q 403 3 have have VBP cord-006870-f5w6fw6q 403 4 demonstrated demonstrate VBN cord-006870-f5w6fw6q 403 5 that that IN cord-006870-f5w6fw6q 403 6 generation generation NN cord-006870-f5w6fw6q 403 7 of of IN cord-006870-f5w6fw6q 403 8 negative negative JJ cord-006870-f5w6fw6q 403 9 intrathoracic intrathoracic JJ cord-006870-f5w6fw6q 403 10 pressure pressure NN cord-006870-f5w6fw6q 403 11 ( ( -LRB- cord-006870-f5w6fw6q 403 12 ITP ITP NNP cord-006870-f5w6fw6q 403 13 ) ) -RRB- cord-006870-f5w6fw6q 403 14 in in IN cord-006870-f5w6fw6q 403 15 ventilated ventilate VBN cord-006870-f5w6fw6q 403 16 patients patient NNS cord-006870-f5w6fw6q 403 17 with with IN cord-006870-f5w6fw6q 403 18 brain brain NN cord-006870-f5w6fw6q 403 19 injury injury NN cord-006870-f5w6fw6q 403 20 improves improve VBZ cord-006870-f5w6fw6q 403 21 mean mean JJ cord-006870-f5w6fw6q 403 22 arterial arterial JJ cord-006870-f5w6fw6q 403 23 pressure pressure NN cord-006870-f5w6fw6q 403 24 ( ( -LRB- cord-006870-f5w6fw6q 403 25 MAP MAP NNP cord-006870-f5w6fw6q 403 26 ) ) -RRB- cord-006870-f5w6fw6q 403 27 and and CC cord-006870-f5w6fw6q 403 28 lowers lower VBZ cord-006870-f5w6fw6q 403 29 intracranial intracranial JJ cord-006870-f5w6fw6q 403 30 pressure pressure NN cord-006870-f5w6fw6q 403 31 ( ( -LRB- cord-006870-f5w6fw6q 403 32 ICP ICP NNP cord-006870-f5w6fw6q 403 33 ) ) -RRB- cord-006870-f5w6fw6q 403 34 . . . cord-006870-f5w6fw6q 404 1 We -PRON- PRP cord-006870-f5w6fw6q 404 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 404 3 that that DT cord-006870-f5w6fw6q 404 4 augmentation augmentation NN cord-006870-f5w6fw6q 404 5 of of IN cord-006870-f5w6fw6q 404 6 negative negative JJ cord-006870-f5w6fw6q 404 7 ITP ITP NNP cord-006870-f5w6fw6q 404 8 by by IN cord-006870-f5w6fw6q 404 9 breathing breathe VBG cord-006870-f5w6fw6q 404 10 through through IN cord-006870-f5w6fw6q 404 11 an an DT cord-006870-f5w6fw6q 404 12 impedance impedance NN cord-006870-f5w6fw6q 404 13 threshold threshold NN cord-006870-f5w6fw6q 404 14 device device NN cord-006870-f5w6fw6q 404 15 ( ( -LRB- cord-006870-f5w6fw6q 404 16 ITD ITD NNP cord-006870-f5w6fw6q 404 17 ) ) -RRB- cord-006870-f5w6fw6q 404 18 with with IN cord-006870-f5w6fw6q 404 19 7 7 CD cord-006870-f5w6fw6q 404 20 cmH2O cmh2o NN cord-006870-f5w6fw6q 404 21 of of IN cord-006870-f5w6fw6q 404 22 inspiratory inspiratory JJ cord-006870-f5w6fw6q 404 23 resistance resistance NN cord-006870-f5w6fw6q 404 24 would would MD cord-006870-f5w6fw6q 404 25 improve improve VB cord-006870-f5w6fw6q 404 26 mean mean JJ cord-006870-f5w6fw6q 404 27 arterial arterial JJ cord-006870-f5w6fw6q 404 28 pressure pressure NN cord-006870-f5w6fw6q 404 29 in in IN cord-006870-f5w6fw6q 404 30 a a DT cord-006870-f5w6fw6q 404 31 porcine porcine JJ cord-006870-f5w6fw6q 404 32 model model NN cord-006870-f5w6fw6q 404 33 of of IN cord-006870-f5w6fw6q 404 34 intracranial intracranial JJ cord-006870-f5w6fw6q 404 35 hypertension hypertension NN cord-006870-f5w6fw6q 404 36 . . . cord-006870-f5w6fw6q 405 1 Six six CD cord-006870-f5w6fw6q 405 2 spontaneously spontaneously RB cord-006870-f5w6fw6q 405 3 breathing breathe VBG cord-006870-f5w6fw6q 405 4 female female JJ cord-006870-f5w6fw6q 405 5 pigs pig NNS cord-006870-f5w6fw6q 405 6 ( ( -LRB- cord-006870-f5w6fw6q 405 7 42.2 42.2 CD cord-006870-f5w6fw6q 405 8 ± ± CD cord-006870-f5w6fw6q 405 9 3.7 3.7 CD cord-006870-f5w6fw6q 405 10 kg kg NNS cord-006870-f5w6fw6q 405 11 ) ) -RRB- cord-006870-f5w6fw6q 405 12 , , , cord-006870-f5w6fw6q 405 13 anesthetized anesthetize VBN cord-006870-f5w6fw6q 405 14 with with IN cord-006870-f5w6fw6q 405 15 propofol propofol NN cord-006870-f5w6fw6q 405 16 , , , cord-006870-f5w6fw6q 405 17 were be VBD cord-006870-f5w6fw6q 405 18 subjected subject VBN cord-006870-f5w6fw6q 405 19 to to IN cord-006870-f5w6fw6q 405 20 focal focal JJ cord-006870-f5w6fw6q 405 21 brain brain NN cord-006870-f5w6fw6q 405 22 injury injury NN cord-006870-f5w6fw6q 405 23 through through IN cord-006870-f5w6fw6q 405 24 inflation inflation NN cord-006870-f5w6fw6q 405 25 of of IN cord-006870-f5w6fw6q 405 26 an an DT cord-006870-f5w6fw6q 405 27 8 8 CD cord-006870-f5w6fw6q 405 28 French french JJ cord-006870-f5w6fw6q 405 29 Foley Foley NNP cord-006870-f5w6fw6q 405 30 catheter catheter NN cord-006870-f5w6fw6q 405 31 placed place VBN cord-006870-f5w6fw6q 405 32 in in IN cord-006870-f5w6fw6q 405 33 the the DT cord-006870-f5w6fw6q 405 34 epidural epidural NN cord-006870-f5w6fw6q 405 35 space space NN cord-006870-f5w6fw6q 405 36 . . . cord-006870-f5w6fw6q 406 1 Once once RB cord-006870-f5w6fw6q 406 2 a a DT cord-006870-f5w6fw6q 406 3 stable stable JJ cord-006870-f5w6fw6q 406 4 injury injury NN cord-006870-f5w6fw6q 406 5 was be VBD cord-006870-f5w6fw6q 406 6 obtained obtain VBN cord-006870-f5w6fw6q 406 7 , , , cord-006870-f5w6fw6q 406 8 baseline baseline JJ cord-006870-f5w6fw6q 406 9 data datum NNS cord-006870-f5w6fw6q 406 10 were be VBD cord-006870-f5w6fw6q 406 11 collected collect VBN cord-006870-f5w6fw6q 406 12 for for IN cord-006870-f5w6fw6q 406 13 20 20 CD cord-006870-f5w6fw6q 406 14 minutes minute NNS cord-006870-f5w6fw6q 406 15 followed follow VBN cord-006870-f5w6fw6q 406 16 by by IN cord-006870-f5w6fw6q 406 17 20 20 CD cord-006870-f5w6fw6q 406 18 minutes minute NNS cord-006870-f5w6fw6q 406 19 of of IN cord-006870-f5w6fw6q 406 20 ITD ITD NNP cord-006870-f5w6fw6q 406 21 use use NN cord-006870-f5w6fw6q 406 22 . . . cord-006870-f5w6fw6q 407 1 Results result NNS cord-006870-f5w6fw6q 407 2 are be VBP cord-006870-f5w6fw6q 407 3 reported report VBN cord-006870-f5w6fw6q 407 4 as as IN cord-006870-f5w6fw6q 407 5 mean mean JJ cord-006870-f5w6fw6q 407 6 ± ± NNP cord-006870-f5w6fw6q 407 7 SD SD NNP cord-006870-f5w6fw6q 407 8 . . . cord-006870-f5w6fw6q 408 1 The the DT cord-006870-f5w6fw6q 408 2 ITP ITP NNP cord-006870-f5w6fw6q 408 3 without without IN cord-006870-f5w6fw6q 408 4 the the DT cord-006870-f5w6fw6q 408 5 ITD itd NN cord-006870-f5w6fw6q 408 6 during during IN cord-006870-f5w6fw6q 408 7 inspiration inspiration NN cord-006870-f5w6fw6q 408 8 was be VBD cord-006870-f5w6fw6q 408 9 -1.0 -1.0 NNP cord-006870-f5w6fw6q 408 10 ± ± NNP cord-006870-f5w6fw6q 408 11 0.4 0.4 CD cord-006870-f5w6fw6q 408 12 mmHg mmHg NNS cord-006870-f5w6fw6q 408 13 , , , cord-006870-f5w6fw6q 408 14 compared compare VBN cord-006870-f5w6fw6q 408 15 to to IN cord-006870-f5w6fw6q 408 16 -9.0 -9.0 NN cord-006870-f5w6fw6q 408 17 ± ± NNP cord-006870-f5w6fw6q 408 18 0.8 0.8 CD cord-006870-f5w6fw6q 408 19 mmHg mmHg NNS cord-006870-f5w6fw6q 408 20 with with IN cord-006870-f5w6fw6q 408 21 the the DT cord-006870-f5w6fw6q 408 22 ITD ITD NNP cord-006870-f5w6fw6q 408 23 , , , cord-006870-f5w6fw6q 408 24 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 408 25 . . . cord-006870-f5w6fw6q 409 1 Following follow VBG cord-006870-f5w6fw6q 409 2 brain brain NN cord-006870-f5w6fw6q 409 3 injury injury NN cord-006870-f5w6fw6q 409 4 , , , cord-006870-f5w6fw6q 409 5 MAP MAP NNP cord-006870-f5w6fw6q 409 6 ( ( -LRB- cord-006870-f5w6fw6q 409 7 mmHg mmHg NNP cord-006870-f5w6fw6q 409 8 ) ) -RRB- cord-006870-f5w6fw6q 409 9 was be VBD cord-006870-f5w6fw6q 409 10 significantly significantly RB cord-006870-f5w6fw6q 409 11 higher high JJR cord-006870-f5w6fw6q 409 12 during during IN cord-006870-f5w6fw6q 409 13 ITD ITD NNP cord-006870-f5w6fw6q 409 14 use use NN cord-006870-f5w6fw6q 409 15 ( ( -LRB- cord-006870-f5w6fw6q 409 16 95 95 CD cord-006870-f5w6fw6q 409 17 ± ± NN cord-006870-f5w6fw6q 410 1 11 11 CD cord-006870-f5w6fw6q 410 2 vs. vs. IN cord-006870-f5w6fw6q 410 3 89 89 CD cord-006870-f5w6fw6q 410 4 ± ± CD cord-006870-f5w6fw6q 410 5 11 11 CD cord-006870-f5w6fw6q 410 6 ; ; : cord-006870-f5w6fw6q 410 7 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 410 8 ) ) -RRB- cord-006870-f5w6fw6q 410 9 . . . cord-006870-f5w6fw6q 411 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 411 2 perfusion perfusion NN cord-006870-f5w6fw6q 411 3 pressure pressure NN cord-006870-f5w6fw6q 411 4 ( ( -LRB- cord-006870-f5w6fw6q 411 5 mmHg mmHg NNP cord-006870-f5w6fw6q 411 6 ) ) -RRB- cord-006870-f5w6fw6q 411 7 was be VBD cord-006870-f5w6fw6q 411 8 also also RB cord-006870-f5w6fw6q 411 9 significantly significantly RB cord-006870-f5w6fw6q 411 10 higher high JJR cord-006870-f5w6fw6q 411 11 during during IN cord-006870-f5w6fw6q 411 12 ITD ITD NNP cord-006870-f5w6fw6q 411 13 use use NN cord-006870-f5w6fw6q 411 14 ( ( -LRB- cord-006870-f5w6fw6q 411 15 75 75 CD cord-006870-f5w6fw6q 411 16 ± ± CD cord-006870-f5w6fw6q 411 17 11 11 CD cord-006870-f5w6fw6q 411 18 vs. vs. NN cord-006870-f5w6fw6q 411 19 69 69 CD cord-006870-f5w6fw6q 411 20 ± ± CD cord-006870-f5w6fw6q 411 21 10 10 CD cord-006870-f5w6fw6q 411 22 ; ; : cord-006870-f5w6fw6q 411 23 p<0.05 p<0.05 CD cord-006870-f5w6fw6q 411 24 ) ) -RRB- cord-006870-f5w6fw6q 411 25 . . . cord-006870-f5w6fw6q 412 1 ICP ICP NNP cord-006870-f5w6fw6q 412 2 ( ( -LRB- cord-006870-f5w6fw6q 412 3 mmHg mmHg NNP cord-006870-f5w6fw6q 412 4 ) ) -RRB- cord-006870-f5w6fw6q 412 5 was be VBD cord-006870-f5w6fw6q 412 6 not not RB cord-006870-f5w6fw6q 412 7 significantly significantly RB cord-006870-f5w6fw6q 412 8 different different JJ cord-006870-f5w6fw6q 412 9 between between IN cord-006870-f5w6fw6q 412 10 groups group NNS cord-006870-f5w6fw6q 412 11 ( ( -LRB- cord-006870-f5w6fw6q 412 12 20.1 20.1 CD cord-006870-f5w6fw6q 412 13 ± ± NNP cord-006870-f5w6fw6q 412 14 3.4 3.4 CD cord-006870-f5w6fw6q 412 15 vs. vs. NN cord-006870-f5w6fw6q 412 16 19.9 19.9 CD cord-006870-f5w6fw6q 412 17 ± ± CD cord-006870-f5w6fw6q 412 18 3.3 3.3 CD cord-006870-f5w6fw6q 412 19 ; ; : cord-006870-f5w6fw6q 412 20 p=0.19 p=0.19 NNP cord-006870-f5w6fw6q 412 21 ) ) -RRB- cord-006870-f5w6fw6q 413 1 although although IN cord-006870-f5w6fw6q 413 2 end end VB cord-006870-f5w6fw6q 413 3 tidal tidal JJ cord-006870-f5w6fw6q 413 4 carbon carbon NN cord-006870-f5w6fw6q 413 5 dioxide dioxide NN cord-006870-f5w6fw6q 413 6 levels level NNS cord-006870-f5w6fw6q 413 7 ( ( -LRB- cord-006870-f5w6fw6q 413 8 mmHg mmHg NNP cord-006870-f5w6fw6q 413 9 ) ) -RRB- cord-006870-f5w6fw6q 413 10 were be VBD cord-006870-f5w6fw6q 413 11 significantly significantly RB cord-006870-f5w6fw6q 413 12 higher high JJR cord-006870-f5w6fw6q 413 13 during during IN cord-006870-f5w6fw6q 413 14 ITD ITD NNP cord-006870-f5w6fw6q 413 15 use use NN cord-006870-f5w6fw6q 413 16 ( ( -LRB- cord-006870-f5w6fw6q 413 17 26 26 CD cord-006870-f5w6fw6q 413 18 ± ± CD cord-006870-f5w6fw6q 413 19 3 3 CD cord-006870-f5w6fw6q 413 20 vs. vs. NN cord-006870-f5w6fw6q 413 21 20 20 CD cord-006870-f5w6fw6q 413 22 ± ± CD cord-006870-f5w6fw6q 413 23 1 1 CD cord-006870-f5w6fw6q 413 24 ; ; : cord-006870-f5w6fw6q 413 25 p<0.005 p<0.005 LS cord-006870-f5w6fw6q 413 26 ) ) -RRB- cord-006870-f5w6fw6q 413 27 presumably presumably RB cord-006870-f5w6fw6q 413 28 due due JJ cord-006870-f5w6fw6q 413 29 to to TO cord-006870-f5w6fw6q 413 30 lower low JJR cord-006870-f5w6fw6q 413 31 respiratory respiratory JJ cord-006870-f5w6fw6q 413 32 rates rate NNS cord-006870-f5w6fw6q 413 33 during during IN cord-006870-f5w6fw6q 413 34 ITD ITD NNP cord-006870-f5w6fw6q 413 35 use use NN cord-006870-f5w6fw6q 413 36 ( ( -LRB- cord-006870-f5w6fw6q 413 37 29 29 CD cord-006870-f5w6fw6q 413 38 ± ± CD cord-006870-f5w6fw6q 413 39 5 5 CD cord-006870-f5w6fw6q 413 40 vs. vs. NN cord-006870-f5w6fw6q 413 41 35 35 CD cord-006870-f5w6fw6q 413 42 ± ± NNP cord-006870-f5w6fw6q 413 43 7 7 CD cord-006870-f5w6fw6q 413 44 ; ; : cord-006870-f5w6fw6q 413 45 p=0.21 p=0.21 NNP cord-006870-f5w6fw6q 413 46 ) ) -RRB- cord-006870-f5w6fw6q 413 47 . . . cord-006870-f5w6fw6q 414 1 Contralateral contralateral JJ cord-006870-f5w6fw6q 414 2 cerebral cerebral JJ cord-006870-f5w6fw6q 414 3 blood blood NN cord-006870-f5w6fw6q 414 4 flow flow NN cord-006870-f5w6fw6q 414 5 ( ( -LRB- cord-006870-f5w6fw6q 414 6 ml/100gm ml/100gm NNP cord-006870-f5w6fw6q 414 7 / / SYM cord-006870-f5w6fw6q 414 8 min min NN cord-006870-f5w6fw6q 414 9 ) ) -RRB- cord-006870-f5w6fw6q 414 10 was be VBD cord-006870-f5w6fw6q 414 11 similar similar JJ cord-006870-f5w6fw6q 414 12 between between IN cord-006870-f5w6fw6q 414 13 groups group NNS cord-006870-f5w6fw6q 414 14 ( ( -LRB- cord-006870-f5w6fw6q 414 15 34 34 CD cord-006870-f5w6fw6q 414 16 ± ± NNP cord-006870-f5w6fw6q 414 17 18 18 CD cord-006870-f5w6fw6q 414 18 vs. vs. NN cord-006870-f5w6fw6q 414 19 34 34 CD cord-006870-f5w6fw6q 414 20 ± ± CD cord-006870-f5w6fw6q 414 21 17 17 CD cord-006870-f5w6fw6q 414 22 ) ) -RRB- cord-006870-f5w6fw6q 414 23 . . . cord-006870-f5w6fw6q 415 1 In in IN cord-006870-f5w6fw6q 415 2 this this DT cord-006870-f5w6fw6q 415 3 porcine porcine JJ cord-006870-f5w6fw6q 415 4 model model NN cord-006870-f5w6fw6q 415 5 of of IN cord-006870-f5w6fw6q 415 6 intracranial intracranial JJ cord-006870-f5w6fw6q 415 7 hypertension hypertension NN cord-006870-f5w6fw6q 415 8 , , , cord-006870-f5w6fw6q 415 9 spontaneous spontaneous JJ cord-006870-f5w6fw6q 415 10 respirations respiration NNS cord-006870-f5w6fw6q 415 11 through through IN cord-006870-f5w6fw6q 415 12 an an DT cord-006870-f5w6fw6q 415 13 ITD ITD NNP cord-006870-f5w6fw6q 415 14 significantly significantly RB cord-006870-f5w6fw6q 415 15 improved improve VBD cord-006870-f5w6fw6q 415 16 MAP MAP NNP cord-006870-f5w6fw6q 415 17 and and CC cord-006870-f5w6fw6q 415 18 CPP CPP NNP cord-006870-f5w6fw6q 415 19 . . . cord-006870-f5w6fw6q 416 1 This this DT cord-006870-f5w6fw6q 416 2 approach approach NN cord-006870-f5w6fw6q 416 3 could could MD cord-006870-f5w6fw6q 416 4 be be VB cord-006870-f5w6fw6q 416 5 utilized utilize VBN cord-006870-f5w6fw6q 416 6 to to TO cord-006870-f5w6fw6q 416 7 prevent prevent VB cord-006870-f5w6fw6q 416 8 hypotensive hypotensive JJ cord-006870-f5w6fw6q 416 9 episodes episode NNS cord-006870-f5w6fw6q 416 10 in in IN cord-006870-f5w6fw6q 416 11 the the DT cord-006870-f5w6fw6q 416 12 setting setting NN cord-006870-f5w6fw6q 416 13 of of IN cord-006870-f5w6fw6q 416 14 brain brain NN cord-006870-f5w6fw6q 416 15 injury injury NN cord-006870-f5w6fw6q 416 16 . . . cord-006870-f5w6fw6q 417 1 The the DT cord-006870-f5w6fw6q 417 2 impact impact NN cord-006870-f5w6fw6q 417 3 of of IN cord-006870-f5w6fw6q 417 4 applying apply VBG cord-006870-f5w6fw6q 417 5 nanotechnology nanotechnology NN cord-006870-f5w6fw6q 417 6 and and CC cord-006870-f5w6fw6q 417 7 biomedical biomedical JJ cord-006870-f5w6fw6q 417 8 engineering engineering NN cord-006870-f5w6fw6q 417 9 to to TO cord-006870-f5w6fw6q 417 10 improve improve VB cord-006870-f5w6fw6q 417 11 the the DT cord-006870-f5w6fw6q 417 12 management management NN cord-006870-f5w6fw6q 417 13 of of IN cord-006870-f5w6fw6q 417 14 patients patient NNS cord-006870-f5w6fw6q 417 15 with with IN cord-006870-f5w6fw6q 417 16 Spinal Spinal NNP cord-006870-f5w6fw6q 417 17 Cord Cord NNP cord-006870-f5w6fw6q 417 18 Injuries Injuries NNPS cord-006870-f5w6fw6q 417 19 ( ( -LRB- cord-006870-f5w6fw6q 417 20 SCI SCI NNP cord-006870-f5w6fw6q 417 21 ) ) -RRB- cord-006870-f5w6fw6q 417 22 is be VBZ cord-006870-f5w6fw6q 417 23 still still RB cord-006870-f5w6fw6q 417 24 not not RB cord-006870-f5w6fw6q 417 25 accurately accurately RB cord-006870-f5w6fw6q 417 26 described describe VBN cord-006870-f5w6fw6q 417 27 , , , cord-006870-f5w6fw6q 417 28 nor nor CC cord-006870-f5w6fw6q 417 29 understood understand VBN cord-006870-f5w6fw6q 417 30 . . . cord-006870-f5w6fw6q 418 1 A a DT cord-006870-f5w6fw6q 418 2 systematic systematic JJ cord-006870-f5w6fw6q 418 3 review review NN cord-006870-f5w6fw6q 418 4 of of IN cord-006870-f5w6fw6q 418 5 the the DT cord-006870-f5w6fw6q 418 6 literature literature NN cord-006870-f5w6fw6q 418 7 was be VBD cord-006870-f5w6fw6q 418 8 conducted conduct VBN cord-006870-f5w6fw6q 418 9 , , , cord-006870-f5w6fw6q 418 10 according accord VBG cord-006870-f5w6fw6q 418 11 to to IN cord-006870-f5w6fw6q 418 12 PRISMA PRISMA NNP cord-006870-f5w6fw6q 418 13 criteria criterion NNS cord-006870-f5w6fw6q 418 14 , , , cord-006870-f5w6fw6q 418 15 to to TO cord-006870-f5w6fw6q 418 16 identify identify VB cord-006870-f5w6fw6q 418 17 publications publication NNS cord-006870-f5w6fw6q 418 18 revolving revolve VBG cord-006870-f5w6fw6q 418 19 around around IN cord-006870-f5w6fw6q 418 20 " " `` cord-006870-f5w6fw6q 418 21 SCI+nanotechnology sci+nanotechnology NN cord-006870-f5w6fw6q 418 22 " " '' cord-006870-f5w6fw6q 418 23 and and CC cord-006870-f5w6fw6q 418 24 " " `` cord-006870-f5w6fw6q 418 25 SCI+Biomedical sci+biomedical JJ cord-006870-f5w6fw6q 418 26 Engineering Engineering NNP cord-006870-f5w6fw6q 418 27 " " '' cord-006870-f5w6fw6q 418 28 indexed index VBN cord-006870-f5w6fw6q 418 29 on on IN cord-006870-f5w6fw6q 418 30 PubMed PubMed NNP cord-006870-f5w6fw6q 418 31 in in IN cord-006870-f5w6fw6q 418 32 the the DT cord-006870-f5w6fw6q 418 33 period period NN cord-006870-f5w6fw6q 418 34 2007 2007 CD cord-006870-f5w6fw6q 418 35 - - SYM cord-006870-f5w6fw6q 418 36 2017 2017 CD cord-006870-f5w6fw6q 418 37 . . . cord-006870-f5w6fw6q 419 1 Furthermore furthermore RB cord-006870-f5w6fw6q 419 2 , , , cord-006870-f5w6fw6q 419 3 the the DT cord-006870-f5w6fw6q 419 4 database database NN cord-006870-f5w6fw6q 419 5 of of IN cord-006870-f5w6fw6q 419 6 clinicaltrials.gov clinicaltrials.gov NNP cord-006870-f5w6fw6q 419 7 was be VBD cord-006870-f5w6fw6q 419 8 searched search VBN cord-006870-f5w6fw6q 419 9 to to TO cord-006870-f5w6fw6q 419 10 highlight highlight VB cord-006870-f5w6fw6q 419 11 the the DT cord-006870-f5w6fw6q 419 12 stage stage NN cord-006870-f5w6fw6q 419 13 of of IN cord-006870-f5w6fw6q 419 14 translation translation NN cord-006870-f5w6fw6q 419 15 of of IN cord-006870-f5w6fw6q 419 16 this this DT cord-006870-f5w6fw6q 419 17 research research NN cord-006870-f5w6fw6q 419 18 into into IN cord-006870-f5w6fw6q 419 19 clinical clinical JJ cord-006870-f5w6fw6q 419 20 practice practice NN cord-006870-f5w6fw6q 419 21 through through IN cord-006870-f5w6fw6q 419 22 randomized randomized JJ cord-006870-f5w6fw6q 419 23 clinical clinical JJ cord-006870-f5w6fw6q 419 24 trials trial NNS cord-006870-f5w6fw6q 419 25 ( ( -LRB- cord-006870-f5w6fw6q 419 26 RCT RCT NNP cord-006870-f5w6fw6q 419 27 ) ) -RRB- cord-006870-f5w6fw6q 419 28 . . . cord-006870-f5w6fw6q 420 1 Finally finally RB cord-006870-f5w6fw6q 420 2 the the DT cord-006870-f5w6fw6q 420 3 USPTO USPTO NNP cord-006870-f5w6fw6q 420 4 database database NN cord-006870-f5w6fw6q 420 5 was be VBD cord-006870-f5w6fw6q 420 6 interrogated interrogate VBN cord-006870-f5w6fw6q 420 7 to to TO cord-006870-f5w6fw6q 420 8 identify identify VB cord-006870-f5w6fw6q 420 9 the the DT cord-006870-f5w6fw6q 420 10 number number NN cord-006870-f5w6fw6q 420 11 of of IN cord-006870-f5w6fw6q 420 12 pertinent pertinent JJ cord-006870-f5w6fw6q 420 13 patents patent NNS cord-006870-f5w6fw6q 420 14 filed file VBN cord-006870-f5w6fw6q 420 15 in in IN cord-006870-f5w6fw6q 420 16 NorthAmerica NorthAmerica NNP cord-006870-f5w6fw6q 420 17 in in IN cord-006870-f5w6fw6q 420 18 the the DT cord-006870-f5w6fw6q 420 19 same same JJ cord-006870-f5w6fw6q 420 20 timeframe timeframe NN cord-006870-f5w6fw6q 420 21 . . . cord-006870-f5w6fw6q 421 1 The the DT cord-006870-f5w6fw6q 421 2 literature literature NN cord-006870-f5w6fw6q 421 3 on on IN cord-006870-f5w6fw6q 421 4 bioengineering bioengineering NN cord-006870-f5w6fw6q 421 5 and and CC cord-006870-f5w6fw6q 421 6 nanotechnology nanotechnology NN cord-006870-f5w6fw6q 421 7 contributions contribution NNS cord-006870-f5w6fw6q 421 8 to to IN cord-006870-f5w6fw6q 421 9 SCI SCI NNP cord-006870-f5w6fw6q 421 10 is be VBZ cord-006870-f5w6fw6q 421 11 exponentially exponentially RB cord-006870-f5w6fw6q 421 12 growing grow VBG cord-006870-f5w6fw6q 421 13 , , , cord-006870-f5w6fw6q 421 14 with with IN cord-006870-f5w6fw6q 421 15 almost almost RB cord-006870-f5w6fw6q 421 16 50 50 CD cord-006870-f5w6fw6q 421 17 % % NN cord-006870-f5w6fw6q 421 18 of of IN cord-006870-f5w6fw6q 421 19 articles article NNS cord-006870-f5w6fw6q 421 20 published publish VBN cord-006870-f5w6fw6q 421 21 between between IN cord-006870-f5w6fw6q 421 22 2015 2015 CD cord-006870-f5w6fw6q 421 23 and and CC cord-006870-f5w6fw6q 421 24 2016 2016 CD cord-006870-f5w6fw6q 421 25 . . . cord-006870-f5w6fw6q 422 1 Its -PRON- PRP$ cord-006870-f5w6fw6q 422 2 quality quality NN cord-006870-f5w6fw6q 422 3 and and CC cord-006870-f5w6fw6q 422 4 the the DT cord-006870-f5w6fw6q 422 5 interest interest NN cord-006870-f5w6fw6q 422 6 of of IN cord-006870-f5w6fw6q 422 7 the the DT cord-006870-f5w6fw6q 422 8 scientific scientific JJ cord-006870-f5w6fw6q 422 9 community community NN cord-006870-f5w6fw6q 422 10 are be VBP cord-006870-f5w6fw6q 422 11 high high JJ cord-006870-f5w6fw6q 422 12 , , , cord-006870-f5w6fw6q 422 13 as as IN cord-006870-f5w6fw6q 422 14 confirmed confirm VBN cord-006870-f5w6fw6q 422 15 by by IN cord-006870-f5w6fw6q 422 16 the the DT cord-006870-f5w6fw6q 422 17 average average JJ cord-006870-f5w6fw6q 422 18 Impact Impact NNP cord-006870-f5w6fw6q 422 19 Factor Factor NNP cord-006870-f5w6fw6q 422 20 ( ( -LRB- cord-006870-f5w6fw6q 422 21 14.9 14.9 CD cord-006870-f5w6fw6q 422 22 ) ) -RRB- cord-006870-f5w6fw6q 422 23 and and CC cord-006870-f5w6fw6q 422 24 the the DT cord-006870-f5w6fw6q 422 25 average average JJ cord-006870-f5w6fw6q 422 26 number number NN cord-006870-f5w6fw6q 422 27 of of IN cord-006870-f5w6fw6q 422 28 citations citation NNS cord-006870-f5w6fw6q 422 29 ( ( -LRB- cord-006870-f5w6fw6q 422 30 5 5 CD cord-006870-f5w6fw6q 422 31 ) ) -RRB- cord-006870-f5w6fw6q 422 32 of of IN cord-006870-f5w6fw6q 422 33 articles article NNS cord-006870-f5w6fw6q 422 34 published publish VBN cord-006870-f5w6fw6q 422 35 in in IN cord-006870-f5w6fw6q 422 36 the the DT cord-006870-f5w6fw6q 422 37 last last JJ cord-006870-f5w6fw6q 422 38 two two CD cord-006870-f5w6fw6q 422 39 years year NNS cord-006870-f5w6fw6q 422 40 . . . cord-006870-f5w6fw6q 423 1 This this DT cord-006870-f5w6fw6q 423 2 field field NN cord-006870-f5w6fw6q 423 3 still still RB cord-006870-f5w6fw6q 423 4 represents represent VBZ cord-006870-f5w6fw6q 423 5 a a DT cord-006870-f5w6fw6q 423 6 niche niche NN cord-006870-f5w6fw6q 423 7 of of IN cord-006870-f5w6fw6q 423 8 SCI SCI NNP cord-006870-f5w6fw6q 423 9 research research NN cord-006870-f5w6fw6q 423 10 : : : cord-006870-f5w6fw6q 423 11 the the DT cord-006870-f5w6fw6q 423 12 56 56 CD cord-006870-f5w6fw6q 423 13 articles article NNS cord-006870-f5w6fw6q 423 14 reviewed review VBN cord-006870-f5w6fw6q 423 15 represent represent VBP cord-006870-f5w6fw6q 423 16 only only RB cord-006870-f5w6fw6q 423 17 1.2 1.2 CD cord-006870-f5w6fw6q 423 18 % % NN cord-006870-f5w6fw6q 423 19 of of IN cord-006870-f5w6fw6q 423 20 all all DT cord-006870-f5w6fw6q 423 21 articles article NNS cord-006870-f5w6fw6q 423 22 on on IN cord-006870-f5w6fw6q 423 23 SCI SCI NNP cord-006870-f5w6fw6q 423 24 published publish VBN cord-006870-f5w6fw6q 423 25 in in IN cord-006870-f5w6fw6q 423 26 the the DT cord-006870-f5w6fw6q 423 27 same same JJ cord-006870-f5w6fw6q 423 28 decade decade NN cord-006870-f5w6fw6q 423 29 . . . cord-006870-f5w6fw6q 424 1 This this DT cord-006870-f5w6fw6q 424 2 trend trend NN cord-006870-f5w6fw6q 424 3 is be VBZ cord-006870-f5w6fw6q 424 4 confirmed confirm VBN cord-006870-f5w6fw6q 424 5 on on IN cord-006870-f5w6fw6q 424 6 clinicaltrials.gov clinicaltrials.gov NNP cord-006870-f5w6fw6q 424 7 : : : cord-006870-f5w6fw6q 424 8 out out IN cord-006870-f5w6fw6q 424 9 of of IN cord-006870-f5w6fw6q 424 10 886 886 CD cord-006870-f5w6fw6q 424 11 RCT RCT NNP cord-006870-f5w6fw6q 424 12 on on IN cord-006870-f5w6fw6q 424 13 SCI SCI NNP cord-006870-f5w6fw6q 424 14 only only RB cord-006870-f5w6fw6q 424 15 few few JJ cord-006870-f5w6fw6q 424 16 focus focus NN cord-006870-f5w6fw6q 424 17 on on IN cord-006870-f5w6fw6q 424 18 the the DT cord-006870-f5w6fw6q 424 19 application application NN cord-006870-f5w6fw6q 424 20 of of IN cord-006870-f5w6fw6q 424 21 those those DT cord-006870-f5w6fw6q 424 22 technologies technology NNS cord-006870-f5w6fw6q 424 23 , , , cord-006870-f5w6fw6q 424 24 furthermore furthermore RB cord-006870-f5w6fw6q 424 25 34 34 CD cord-006870-f5w6fw6q 424 26 out out IN cord-006870-f5w6fw6q 424 27 of of IN cord-006870-f5w6fw6q 424 28 40 40 CD cord-006870-f5w6fw6q 424 29 articles article NNS cord-006870-f5w6fw6q 424 30 spurring spur VBG cord-006870-f5w6fw6q 424 31 from from IN cord-006870-f5w6fw6q 424 32 the the DT cord-006870-f5w6fw6q 424 33 RCT RCT NNP cord-006870-f5w6fw6q 424 34 identified identify VBN cord-006870-f5w6fw6q 424 35 were be VBD cord-006870-f5w6fw6q 424 36 published publish VBN cord-006870-f5w6fw6q 424 37 after after IN cord-006870-f5w6fw6q 424 38 2010 2010 CD cord-006870-f5w6fw6q 424 39 , , , cord-006870-f5w6fw6q 424 40 and and CC cord-006870-f5w6fw6q 424 41 25 25 CD cord-006870-f5w6fw6q 424 42 % % NN cord-006870-f5w6fw6q 424 43 after after IN cord-006870-f5w6fw6q 424 44 2016 2016 CD cord-006870-f5w6fw6q 424 45 . . . cord-006870-f5w6fw6q 425 1 Interestingly interestingly RB cord-006870-f5w6fw6q 425 2 , , , cord-006870-f5w6fw6q 425 3 with with IN cord-006870-f5w6fw6q 425 4 119 119 CD cord-006870-f5w6fw6q 425 5 patents patent NNS cord-006870-f5w6fw6q 425 6 registered register VBN cord-006870-f5w6fw6q 425 7 by by IN cord-006870-f5w6fw6q 425 8 the the DT cord-006870-f5w6fw6q 425 9 USPTO USPTO NNP cord-006870-f5w6fw6q 425 10 , , , cord-006870-f5w6fw6q 425 11 the the DT cord-006870-f5w6fw6q 425 12 interest interest NN cord-006870-f5w6fw6q 425 13 in in IN cord-006870-f5w6fw6q 425 14 the the DT cord-006870-f5w6fw6q 425 15 commercial commercial JJ cord-006870-f5w6fw6q 425 16 application application NN cord-006870-f5w6fw6q 425 17 of of IN cord-006870-f5w6fw6q 425 18 this this DT cord-006870-f5w6fw6q 425 19 research research NN cord-006870-f5w6fw6q 425 20 seems seem VBZ cord-006870-f5w6fw6q 425 21 vivid vivid JJ cord-006870-f5w6fw6q 425 22 . . . cord-006870-f5w6fw6q 426 1 Currently currently RB cord-006870-f5w6fw6q 426 2 , , , cord-006870-f5w6fw6q 426 3 the the DT cord-006870-f5w6fw6q 426 4 most most RBS cord-006870-f5w6fw6q 426 5 promising promising JJ cord-006870-f5w6fw6q 426 6 areas area NNS cord-006870-f5w6fw6q 426 7 of of IN cord-006870-f5w6fw6q 426 8 research research NN cord-006870-f5w6fw6q 426 9 are be VBP cord-006870-f5w6fw6q 426 10 : : : cord-006870-f5w6fw6q 426 11 nanofabrication nanofabrication NN cord-006870-f5w6fw6q 426 12 / / SYM cord-006870-f5w6fw6q 426 13 nanoscaffolding nanoscaffolde VBG cord-006870-f5w6fw6q 426 14 for for IN cord-006870-f5w6fw6q 426 15 structural structural JJ cord-006870-f5w6fw6q 426 16 repair repair NN cord-006870-f5w6fw6q 426 17 , , , cord-006870-f5w6fw6q 426 18 nanodrugs nanodrugs NNP cord-006870-f5w6fw6q 426 19 for for IN cord-006870-f5w6fw6q 426 20 regeneration regeneration NN cord-006870-f5w6fw6q 426 21 , , , cord-006870-f5w6fw6q 426 22 and and CC cord-006870-f5w6fw6q 426 23 design design NN cord-006870-f5w6fw6q 426 24 of of IN cord-006870-f5w6fw6q 426 25 neural neural JJ cord-006870-f5w6fw6q 426 26 interfaces interface NNS cord-006870-f5w6fw6q 426 27 for for IN cord-006870-f5w6fw6q 426 28 functional functional JJ cord-006870-f5w6fw6q 426 29 therapies therapy NNS cord-006870-f5w6fw6q 426 30 . . . cord-006870-f5w6fw6q 427 1 This this DT cord-006870-f5w6fw6q 427 2 review review NN cord-006870-f5w6fw6q 427 3 showed show VBD cord-006870-f5w6fw6q 427 4 that that IN cord-006870-f5w6fw6q 427 5 both both DT cord-006870-f5w6fw6q 427 6 universities university NNS cord-006870-f5w6fw6q 427 7 and and CC cord-006870-f5w6fw6q 427 8 independent independent JJ cord-006870-f5w6fw6q 427 9 research research NN cord-006870-f5w6fw6q 427 10 institutions institution NNS cord-006870-f5w6fw6q 427 11 ( ( -LRB- cord-006870-f5w6fw6q 427 12 mostly mostly RB cord-006870-f5w6fw6q 427 13 from from IN cord-006870-f5w6fw6q 427 14 USA USA NNP cord-006870-f5w6fw6q 427 15 , , , cord-006870-f5w6fw6q 427 16 China China NNP cord-006870-f5w6fw6q 427 17 and and CC cord-006870-f5w6fw6q 427 18 European European NNP cord-006870-f5w6fw6q 427 19 Union Union NNP cord-006870-f5w6fw6q 427 20 ) ) -RRB- cord-006870-f5w6fw6q 427 21 are be VBP cord-006870-f5w6fw6q 427 22 driving drive VBG cord-006870-f5w6fw6q 427 23 this this DT cord-006870-f5w6fw6q 427 24 research research NN cord-006870-f5w6fw6q 427 25 race race NN cord-006870-f5w6fw6q 427 26 ; ; : cord-006870-f5w6fw6q 427 27 the the DT cord-006870-f5w6fw6q 427 28 figures figure NNS cord-006870-f5w6fw6q 427 29 provided provide VBN cord-006870-f5w6fw6q 427 30 above above RB cord-006870-f5w6fw6q 427 31 suggest suggest VBP cord-006870-f5w6fw6q 427 32 its -PRON- PRP$ cord-006870-f5w6fw6q 427 33 potential potential NN cord-006870-f5w6fw6q 427 34 to to TO cord-006870-f5w6fw6q 427 35 become become VB cord-006870-f5w6fw6q 427 36 a a DT cord-006870-f5w6fw6q 427 37 successful successful JJ cord-006870-f5w6fw6q 427 38 example example NN cord-006870-f5w6fw6q 427 39 of of IN cord-006870-f5w6fw6q 427 40 translational translational JJ cord-006870-f5w6fw6q 427 41 medicine medicine NN cord-006870-f5w6fw6q 427 42 . . . cord-006870-f5w6fw6q 428 1 There there EX cord-006870-f5w6fw6q 428 2 are be VBP cord-006870-f5w6fw6q 428 3 no no DT cord-006870-f5w6fw6q 428 4 neuroprotective neuroprotective JJ cord-006870-f5w6fw6q 428 5 and and CC cord-006870-f5w6fw6q 428 6 neuroregenerative neuroregenerative JJ cord-006870-f5w6fw6q 428 7 treatments treatment NNS cord-006870-f5w6fw6q 428 8 available available JJ cord-006870-f5w6fw6q 428 9 for for IN cord-006870-f5w6fw6q 428 10 Traumatic traumatic JJ cord-006870-f5w6fw6q 428 11 Brain Brain NNP cord-006870-f5w6fw6q 428 12 Injury Injury NNP cord-006870-f5w6fw6q 428 13 ( ( -LRB- cord-006870-f5w6fw6q 428 14 TBI TBI NNP cord-006870-f5w6fw6q 428 15 ) ) -RRB- cord-006870-f5w6fw6q 428 16 . . . cord-006870-f5w6fw6q 429 1 Clinical clinical JJ cord-006870-f5w6fw6q 429 2 trials trial NNS cord-006870-f5w6fw6q 429 3 investigating investigate VBG cord-006870-f5w6fw6q 429 4 potential potential JJ cord-006870-f5w6fw6q 429 5 treatments treatment NNS cord-006870-f5w6fw6q 429 6 such such JJ cord-006870-f5w6fw6q 429 7 as as IN cord-006870-f5w6fw6q 429 8 therapeutic therapeutic JJ cord-006870-f5w6fw6q 429 9 hypothermia hypothermia NN cord-006870-f5w6fw6q 429 10 and and CC cord-006870-f5w6fw6q 429 11 progesterone progesterone NN cord-006870-f5w6fw6q 429 12 have have VBP cord-006870-f5w6fw6q 429 13 failed fail VBN cord-006870-f5w6fw6q 429 14 . . . cord-006870-f5w6fw6q 430 1 Pre pre JJ cord-006870-f5w6fw6q 430 2 - - JJ cord-006870-f5w6fw6q 430 3 clinical clinical JJ cord-006870-f5w6fw6q 430 4 studies study NNS cord-006870-f5w6fw6q 430 5 indicate indicate VBP cord-006870-f5w6fw6q 430 6 there there EX cord-006870-f5w6fw6q 430 7 may may MD cord-006870-f5w6fw6q 430 8 be be VB cord-006870-f5w6fw6q 430 9 a a DT cord-006870-f5w6fw6q 430 10 role role NN cord-006870-f5w6fw6q 430 11 of of IN cord-006870-f5w6fw6q 430 12 stem stem NN cord-006870-f5w6fw6q 430 13 - - HYPH cord-006870-f5w6fw6q 430 14 cells cell NNS cord-006870-f5w6fw6q 430 15 in in IN cord-006870-f5w6fw6q 430 16 promoting promote VBG cord-006870-f5w6fw6q 430 17 neuroprotection neuroprotection NN cord-006870-f5w6fw6q 430 18 / / SYM cord-006870-f5w6fw6q 430 19 neuroregeneration neuroregeneration NN cord-006870-f5w6fw6q 430 20 in in IN cord-006870-f5w6fw6q 430 21 - - HYPH cord-006870-f5w6fw6q 430 22 vivo vivo NN cord-006870-f5w6fw6q 430 23 in in IN cord-006870-f5w6fw6q 430 24 animal animal NN cord-006870-f5w6fw6q 430 25 models model NNS cord-006870-f5w6fw6q 430 26 of of IN cord-006870-f5w6fw6q 430 27 TBI TBI NNP cord-006870-f5w6fw6q 430 28 . . . cord-006870-f5w6fw6q 431 1 We -PRON- PRP cord-006870-f5w6fw6q 431 2 aim aim VBP cord-006870-f5w6fw6q 431 3 to to TO cord-006870-f5w6fw6q 431 4 provide provide VB cord-006870-f5w6fw6q 431 5 a a DT cord-006870-f5w6fw6q 431 6 pre pre JJ cord-006870-f5w6fw6q 431 7 - - JJ cord-006870-f5w6fw6q 431 8 clinical clinical JJ cord-006870-f5w6fw6q 431 9 literature literature NN cord-006870-f5w6fw6q 431 10 review review NN cord-006870-f5w6fw6q 431 11 into into IN cord-006870-f5w6fw6q 431 12 stem stem NN cord-006870-f5w6fw6q 431 13 - - HYPH cord-006870-f5w6fw6q 431 14 cells cell NNS cord-006870-f5w6fw6q 431 15 as as IN cord-006870-f5w6fw6q 431 16 a a DT cord-006870-f5w6fw6q 431 17 potential potential JJ cord-006870-f5w6fw6q 431 18 therapeutic therapeutic JJ cord-006870-f5w6fw6q 431 19 option option NN cord-006870-f5w6fw6q 431 20 in in IN cord-006870-f5w6fw6q 431 21 TBI tbi NN cord-006870-f5w6fw6q 431 22 - - HYPH cord-006870-f5w6fw6q 431 23 animal animal NN cord-006870-f5w6fw6q 431 24 models model NNS cord-006870-f5w6fw6q 431 25 . . . cord-006870-f5w6fw6q 432 1 A a DT cord-006870-f5w6fw6q 432 2 literature literature NN cord-006870-f5w6fw6q 432 3 search search NN cord-006870-f5w6fw6q 432 4 was be VBD cord-006870-f5w6fw6q 432 5 conducted conduct VBN cord-006870-f5w6fw6q 432 6 on on IN cord-006870-f5w6fw6q 432 7 Pubmed Pubmed NNP cord-006870-f5w6fw6q 432 8 and and CC cord-006870-f5w6fw6q 432 9 Google Google NNP cord-006870-f5w6fw6q 432 10 Scholar scholar NN cord-006870-f5w6fw6q 432 11 using use VBG cord-006870-f5w6fw6q 432 12 the the DT cord-006870-f5w6fw6q 432 13 terms term NNS cord-006870-f5w6fw6q 432 14 " " `` cord-006870-f5w6fw6q 432 15 traumatic traumatic JJ cord-006870-f5w6fw6q 432 16 brain brain NN cord-006870-f5w6fw6q 432 17 injury injury NN cord-006870-f5w6fw6q 432 18 " " '' cord-006870-f5w6fw6q 432 19 , , , cord-006870-f5w6fw6q 432 20 " " `` cord-006870-f5w6fw6q 432 21 stem stem NN cord-006870-f5w6fw6q 432 22 - - HYPH cord-006870-f5w6fw6q 432 23 cell cell NN cord-006870-f5w6fw6q 432 24 " " '' cord-006870-f5w6fw6q 432 25 , , , cord-006870-f5w6fw6q 432 26 " " `` cord-006870-f5w6fw6q 432 27 preclinical preclinical JJ cord-006870-f5w6fw6q 432 28 " " '' cord-006870-f5w6fw6q 432 29 , , , cord-006870-f5w6fw6q 432 30 and and CC cord-006870-f5w6fw6q 432 31 " " `` cord-006870-f5w6fw6q 432 32 animal animal NN cord-006870-f5w6fw6q 432 33 studies study NNS cord-006870-f5w6fw6q 432 34 " " '' cord-006870-f5w6fw6q 432 35 . . . cord-006870-f5w6fw6q 433 1 Studies study NNS cord-006870-f5w6fw6q 433 2 were be VBD cord-006870-f5w6fw6q 433 3 included include VBN cord-006870-f5w6fw6q 433 4 if if IN cord-006870-f5w6fw6q 433 5 there there EX cord-006870-f5w6fw6q 433 6 was be VBD cord-006870-f5w6fw6q 433 7 an an DT cord-006870-f5w6fw6q 433 8 in in IN cord-006870-f5w6fw6q 433 9 - - HYPH cord-006870-f5w6fw6q 433 10 vivo vivo NN cord-006870-f5w6fw6q 433 11 animal animal NN cord-006870-f5w6fw6q 433 12 model model NN cord-006870-f5w6fw6q 433 13 of of IN cord-006870-f5w6fw6q 433 14 TBI TBI NNP cord-006870-f5w6fw6q 433 15 with with IN cord-006870-f5w6fw6q 433 16 either either CC cord-006870-f5w6fw6q 433 17 intravenous intravenous JJ cord-006870-f5w6fw6q 433 18 or or CC cord-006870-f5w6fw6q 433 19 intra intra JJ cord-006870-f5w6fw6q 433 20 - - JJ cord-006870-f5w6fw6q 433 21 cortical cortical JJ cord-006870-f5w6fw6q 433 22 stem stem NN cord-006870-f5w6fw6q 433 23 - - HYPH cord-006870-f5w6fw6q 433 24 cell cell NN cord-006870-f5w6fw6q 433 25 transplantation transplantation NN cord-006870-f5w6fw6q 433 26 , , , cord-006870-f5w6fw6q 433 27 along along RB cord-006870-f5w6fw6q 433 28 - - , cord-006870-f5w6fw6q 433 29 with with IN cord-006870-f5w6fw6q 433 30 a a DT cord-006870-f5w6fw6q 433 31 control control NN cord-006870-f5w6fw6q 433 32 group group NN cord-006870-f5w6fw6q 433 33 , , , cord-006870-f5w6fw6q 433 34 and and CC cord-006870-f5w6fw6q 433 35 investigated investigate VBN cord-006870-f5w6fw6q 433 36 either either CC cord-006870-f5w6fw6q 433 37 motor motor NN cord-006870-f5w6fw6q 433 38 or or CC cord-006870-f5w6fw6q 433 39 behavioral behavioral JJ cord-006870-f5w6fw6q 433 40 outcomes outcome NNS cord-006870-f5w6fw6q 433 41 , , , cord-006870-f5w6fw6q 433 42 or or CC cord-006870-f5w6fw6q 433 43 a a DT cord-006870-f5w6fw6q 433 44 combination combination NN cord-006870-f5w6fw6q 433 45 . . . cord-006870-f5w6fw6q 434 1 Twenty twenty CD cord-006870-f5w6fw6q 434 2 - - HYPH cord-006870-f5w6fw6q 434 3 seven seven CD cord-006870-f5w6fw6q 434 4 studies study NNS cord-006870-f5w6fw6q 434 5 ( ( -LRB- cord-006870-f5w6fw6q 434 6 n=1184 n=1184 CD cord-006870-f5w6fw6q 434 7 animals animal NNS cord-006870-f5w6fw6q 434 8 ) ) -RRB- cord-006870-f5w6fw6q 434 9 satisfied satisfy VBD cord-006870-f5w6fw6q 434 10 the the DT cord-006870-f5w6fw6q 434 11 criteria criterion NNS cord-006870-f5w6fw6q 434 12 . . . cord-006870-f5w6fw6q 435 1 774/1184 774/1184 LS cord-006870-f5w6fw6q 435 2 ( ( -LRB- cord-006870-f5w6fw6q 435 3 65.4 65.4 CD cord-006870-f5w6fw6q 435 4 % % NN cord-006870-f5w6fw6q 435 5 ) ) -RRB- cord-006870-f5w6fw6q 435 6 animals animal NNS cord-006870-f5w6fw6q 435 7 were be VBD cord-006870-f5w6fw6q 435 8 investigated investigate VBN cord-006870-f5w6fw6q 435 9 for for IN cord-006870-f5w6fw6q 435 10 outcomes outcome NNS cord-006870-f5w6fw6q 435 11 . . . cord-006870-f5w6fw6q 436 1 17 17 CD cord-006870-f5w6fw6q 436 2 studies study NNS cord-006870-f5w6fw6q 436 3 harvested harvest VBD cord-006870-f5w6fw6q 436 4 stem stem NN cord-006870-f5w6fw6q 436 5 - - HYPH cord-006870-f5w6fw6q 436 6 cells cell NNS cord-006870-f5w6fw6q 436 7 from from IN cord-006870-f5w6fw6q 436 8 human human JJ cord-006870-f5w6fw6q 436 9 - - HYPH cord-006870-f5w6fw6q 436 10 source source NN cord-006870-f5w6fw6q 436 11 , , , cord-006870-f5w6fw6q 436 12 whereas whereas IN cord-006870-f5w6fw6q 436 13 10 10 CD cord-006870-f5w6fw6q 436 14 harvested harvest VBN cord-006870-f5w6fw6q 436 15 stem stem NN cord-006870-f5w6fw6q 436 16 - - HYPH cord-006870-f5w6fw6q 436 17 cells cell NNS cord-006870-f5w6fw6q 436 18 from from IN cord-006870-f5w6fw6q 436 19 animal animal NN cord-006870-f5w6fw6q 436 20 - - HYPH cord-006870-f5w6fw6q 436 21 source source NN cord-006870-f5w6fw6q 436 22 . . . cord-006870-f5w6fw6q 437 1 Bone bone NN cord-006870-f5w6fw6q 437 2 - - HYPH cord-006870-f5w6fw6q 437 3 marrow marrow NN cord-006870-f5w6fw6q 437 4 stromal stromal NN cord-006870-f5w6fw6q 437 5 - - HYPH cord-006870-f5w6fw6q 437 6 cells cell NNS cord-006870-f5w6fw6q 437 7 ( ( -LRB- cord-006870-f5w6fw6q 437 8 BMSC BMSC NNP cord-006870-f5w6fw6q 437 9 ) ) -RRB- cord-006870-f5w6fw6q 437 10 were be VBD cord-006870-f5w6fw6q 437 11 used use VBN cord-006870-f5w6fw6q 437 12 in in IN cord-006870-f5w6fw6q 437 13 17 17 CD cord-006870-f5w6fw6q 437 14 studies study NNS cord-006870-f5w6fw6q 437 15 , , , cord-006870-f5w6fw6q 437 16 neural neural NNP cord-006870-f5w6fw6q 437 17 stemcells stemcells NNP cord-006870-f5w6fw6q 437 18 ( ( -LRB- cord-006870-f5w6fw6q 437 19 NSC NSC NNP cord-006870-f5w6fw6q 437 20 ) ) -RRB- cord-006870-f5w6fw6q 437 21 in in IN cord-006870-f5w6fw6q 437 22 7 7 CD cord-006870-f5w6fw6q 437 23 , , , cord-006870-f5w6fw6q 437 24 and and CC cord-006870-f5w6fw6q 437 25 miscellaneous miscellaneous JJ cord-006870-f5w6fw6q 437 26 in in IN cord-006870-f5w6fw6q 437 27 3 3 CD cord-006870-f5w6fw6q 437 28 . . . cord-006870-f5w6fw6q 438 1 450/774 450/774 LS cord-006870-f5w6fw6q 438 2 ( ( -LRB- cord-006870-f5w6fw6q 438 3 58.1 58.1 CD cord-006870-f5w6fw6q 438 4 % % NN cord-006870-f5w6fw6q 438 5 ) ) -RRB- cord-006870-f5w6fw6q 438 6 animals animal NNS cord-006870-f5w6fw6q 438 7 received receive VBD cord-006870-f5w6fw6q 438 8 any any DT cord-006870-f5w6fw6q 438 9 stem stem NN cord-006870-f5w6fw6q 438 10 - - HYPH cord-006870-f5w6fw6q 438 11 cell cell NN cord-006870-f5w6fw6q 438 12 transplantation transplantation NN cord-006870-f5w6fw6q 438 13 , , , cord-006870-f5w6fw6q 438 14 whereas whereas IN cord-006870-f5w6fw6q 438 15 324 324 CD cord-006870-f5w6fw6q 438 16 were be VBD cord-006870-f5w6fw6q 438 17 controls control NNS cord-006870-f5w6fw6q 438 18 . . . cord-006870-f5w6fw6q 439 1 Of of IN cord-006870-f5w6fw6q 439 2 animals animal NNS cord-006870-f5w6fw6q 439 3 receiving receive VBG cord-006870-f5w6fw6q 439 4 stem stem NN cord-006870-f5w6fw6q 439 5 - - HYPH cord-006870-f5w6fw6q 439 6 cell cell NN cord-006870-f5w6fw6q 439 7 transplantation transplantation NN cord-006870-f5w6fw6q 439 8 ( ( -LRB- cord-006870-f5w6fw6q 439 9 450 450 CD cord-006870-f5w6fw6q 439 10 ) ) -RRB- cord-006870-f5w6fw6q 439 11 , , , cord-006870-f5w6fw6q 439 12 339 339 CD cord-006870-f5w6fw6q 439 13 ( ( -LRB- cord-006870-f5w6fw6q 439 14 75.3 75.3 CD cord-006870-f5w6fw6q 439 15 % % NN cord-006870-f5w6fw6q 439 16 ) ) -RRB- cord-006870-f5w6fw6q 439 17 showed show VBD cord-006870-f5w6fw6q 439 18 significantly significantly RB cord-006870-f5w6fw6q 439 19 better well JJR cord-006870-f5w6fw6q 439 20 outcomes outcome NNS cord-006870-f5w6fw6q 439 21 relative relative JJ cord-006870-f5w6fw6q 439 22 to to TO cord-006870-f5w6fw6q 439 23 control control VB cord-006870-f5w6fw6q 439 24 animals animal NNS cord-006870-f5w6fw6q 439 25 in in IN cord-006870-f5w6fw6q 439 26 each each DT cord-006870-f5w6fw6q 439 27 individual individual JJ cord-006870-f5w6fw6q 439 28 study study NN cord-006870-f5w6fw6q 439 29 , , , cord-006870-f5w6fw6q 439 30 with with IN cord-006870-f5w6fw6q 439 31 exception exception NN cord-006870-f5w6fw6q 439 32 of of IN cord-006870-f5w6fw6q 439 33 one one CD cord-006870-f5w6fw6q 439 34 study study NN cord-006870-f5w6fw6q 439 35 . . . cord-006870-f5w6fw6q 440 1 Amongst amongst IN cord-006870-f5w6fw6q 440 2 transplanted transplant VBN cord-006870-f5w6fw6q 440 3 animals animal NNS cord-006870-f5w6fw6q 440 4 , , , cord-006870-f5w6fw6q 440 5 functional functional JJ cord-006870-f5w6fw6q 440 6 outcomes outcome NNS cord-006870-f5w6fw6q 440 7 did do VBD cord-006870-f5w6fw6q 440 8 not not RB cord-006870-f5w6fw6q 440 9 differ differ VB cord-006870-f5w6fw6q 440 10 significantly significantly RB cord-006870-f5w6fw6q 440 11 when when WRB cord-006870-f5w6fw6q 440 12 grouped group VBN cord-006870-f5w6fw6q 440 13 by by IN cord-006870-f5w6fw6q 440 14 stem stem NN cord-006870-f5w6fw6q 440 15 - - HYPH cord-006870-f5w6fw6q 440 16 cell cell NN cord-006870-f5w6fw6q 440 17 type type NN cord-006870-f5w6fw6q 440 18 ( ( -LRB- cord-006870-f5w6fw6q 440 19 p=0.553 p=0.553 NNP cord-006870-f5w6fw6q 440 20 ) ) -RRB- cord-006870-f5w6fw6q 440 21 , , , cord-006870-f5w6fw6q 440 22 transplantation transplantation NN cord-006870-f5w6fw6q 440 23 route route NN cord-006870-f5w6fw6q 440 24 ( ( -LRB- cord-006870-f5w6fw6q 440 25 p=0.054 p=0.054 NNP cord-006870-f5w6fw6q 440 26 ) ) -RRB- cord-006870-f5w6fw6q 440 27 , , , cord-006870-f5w6fw6q 440 28 and and CC cord-006870-f5w6fw6q 440 29 source source NN cord-006870-f5w6fw6q 440 30 ( ( -LRB- cord-006870-f5w6fw6q 440 31 p=0.784 p=0.784 NNP cord-006870-f5w6fw6q 440 32 ) ) -RRB- cord-006870-f5w6fw6q 440 33 . . . cord-006870-f5w6fw6q 441 1 Animals animal NNS cord-006870-f5w6fw6q 441 2 were be VBD cord-006870-f5w6fw6q 441 3 followedup followedup NNP cord-006870-f5w6fw6q 441 4 until until IN cord-006870-f5w6fw6q 441 5 1 1 CD cord-006870-f5w6fw6q 441 6 week week NN cord-006870-f5w6fw6q 441 7 ( ( -LRB- cord-006870-f5w6fw6q 441 8 n=5 n=5 NNP cord-006870-f5w6fw6q 441 9 studies studies NNPS cord-006870-f5w6fw6q 441 10 ) ) -RRB- cord-006870-f5w6fw6q 441 11 , , , cord-006870-f5w6fw6q 441 12 2 2 CD cord-006870-f5w6fw6q 441 13 weeks week NNS cord-006870-f5w6fw6q 441 14 ( ( -LRB- cord-006870-f5w6fw6q 441 15 n=10 n=10 NNP cord-006870-f5w6fw6q 441 16 ) ) -RRB- cord-006870-f5w6fw6q 441 17 , , , cord-006870-f5w6fw6q 441 18 4 4 CD cord-006870-f5w6fw6q 441 19 weeks week NNS cord-006870-f5w6fw6q 441 20 ( ( -LRB- cord-006870-f5w6fw6q 441 21 n=5 n=5 NNP cord-006870-f5w6fw6q 441 22 ) ) -RRB- cord-006870-f5w6fw6q 441 23 , , , cord-006870-f5w6fw6q 441 24 or or CC cord-006870-f5w6fw6q 441 25 > > XX cord-006870-f5w6fw6q 441 26 4-weeks 4-weeks CD cord-006870-f5w6fw6q 441 27 ( ( -LRB- cord-006870-f5w6fw6q 441 28 n=7 n=7 NNS cord-006870-f5w6fw6q 441 29 ) ) -RRB- cord-006870-f5w6fw6q 441 30 . . . cord-006870-f5w6fw6q 442 1 This this DT cord-006870-f5w6fw6q 442 2 pre pre JJ cord-006870-f5w6fw6q 442 3 - - JJ cord-006870-f5w6fw6q 442 4 clinical clinical JJ cord-006870-f5w6fw6q 442 5 data data NN cord-006870-f5w6fw6q 442 6 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 442 7 that that IN cord-006870-f5w6fw6q 442 8 stem stem NN cord-006870-f5w6fw6q 442 9 - - HYPH cord-006870-f5w6fw6q 442 10 cell cell NN cord-006870-f5w6fw6q 442 11 transplantation transplantation NN cord-006870-f5w6fw6q 442 12 may may MD cord-006870-f5w6fw6q 442 13 have have VB cord-006870-f5w6fw6q 442 14 treatment treatment NN cord-006870-f5w6fw6q 442 15 potential potential NN cord-006870-f5w6fw6q 442 16 in in IN cord-006870-f5w6fw6q 442 17 TBI TBI NNP cord-006870-f5w6fw6q 442 18 as as IN cord-006870-f5w6fw6q 442 19 shown show VBN cord-006870-f5w6fw6q 442 20 by by IN cord-006870-f5w6fw6q 442 21 improvement improvement NN cord-006870-f5w6fw6q 442 22 in in IN cord-006870-f5w6fw6q 442 23 functional functional JJ cord-006870-f5w6fw6q 442 24 outcome outcome NN cord-006870-f5w6fw6q 442 25 in in IN cord-006870-f5w6fw6q 442 26 as as RB cord-006870-f5w6fw6q 442 27 many many JJ cord-006870-f5w6fw6q 442 28 as as IN cord-006870-f5w6fw6q 442 29 three three CD cord-006870-f5w6fw6q 442 30 - - HYPH cord-006870-f5w6fw6q 442 31 quarters quarter NNS cord-006870-f5w6fw6q 442 32 of of IN cord-006870-f5w6fw6q 442 33 all all DT cord-006870-f5w6fw6q 442 34 animals animal NNS cord-006870-f5w6fw6q 442 35 that that WDT cord-006870-f5w6fw6q 442 36 were be VBD cord-006870-f5w6fw6q 442 37 treated treat VBN cord-006870-f5w6fw6q 442 38 with with IN cord-006870-f5w6fw6q 442 39 stem stem NN cord-006870-f5w6fw6q 442 40 - - HYPH cord-006870-f5w6fw6q 442 41 cells cell NNS cord-006870-f5w6fw6q 442 42 . . . cord-006870-f5w6fw6q 443 1 This this DT cord-006870-f5w6fw6q 443 2 data data NN cord-006870-f5w6fw6q 443 3 provides provide VBZ cord-006870-f5w6fw6q 443 4 a a DT cord-006870-f5w6fw6q 443 5 foundation foundation NN cord-006870-f5w6fw6q 443 6 for for IN cord-006870-f5w6fw6q 443 7 the the DT cord-006870-f5w6fw6q 443 8 design design NN cord-006870-f5w6fw6q 443 9 of of IN cord-006870-f5w6fw6q 443 10 clinical clinical JJ cord-006870-f5w6fw6q 443 11 translational translational JJ cord-006870-f5w6fw6q 443 12 studies study NNS cord-006870-f5w6fw6q 443 13 . . . cord-006870-f5w6fw6q 444 1 Age age NN cord-006870-f5w6fw6q 444 2 of of IN cord-006870-f5w6fw6q 444 3 trauma trauma NN cord-006870-f5w6fw6q 444 4 patients patient NNS cord-006870-f5w6fw6q 444 5 including include VBG cord-006870-f5w6fw6q 444 6 those those DT cord-006870-f5w6fw6q 444 7 with with IN cord-006870-f5w6fw6q 444 8 aSDH asdh CD cord-006870-f5w6fw6q 444 9 is be VBZ cord-006870-f5w6fw6q 444 10 increasing increase VBG cord-006870-f5w6fw6q 444 11 as as IN cord-006870-f5w6fw6q 444 12 stated state VBN cord-006870-f5w6fw6q 444 13 by by IN cord-006870-f5w6fw6q 444 14 national national JJ cord-006870-f5w6fw6q 444 15 trauma trauma NN cord-006870-f5w6fw6q 444 16 registers register NNS cord-006870-f5w6fw6q 444 17 . . . cord-006870-f5w6fw6q 445 1 We -PRON- PRP cord-006870-f5w6fw6q 445 2 were be VBD cord-006870-f5w6fw6q 445 3 especially especially RB cord-006870-f5w6fw6q 445 4 interested interested JJ cord-006870-f5w6fw6q 446 1 if if IN cord-006870-f5w6fw6q 446 2 age age NN cord-006870-f5w6fw6q 446 3 > > XX cord-006870-f5w6fw6q 446 4 65 65 CD cord-006870-f5w6fw6q 446 5 years year NNS cord-006870-f5w6fw6q 446 6 significantly significantly RB cord-006870-f5w6fw6q 446 7 influences influence VBZ cord-006870-f5w6fw6q 446 8 outcome outcome VBP cord-006870-f5w6fw6q 446 9 compared compare VBN cord-006870-f5w6fw6q 446 10 to to IN cord-006870-f5w6fw6q 446 11 younger young JJR cord-006870-f5w6fw6q 446 12 patients patient NNS cord-006870-f5w6fw6q 446 13 and and CC cord-006870-f5w6fw6q 446 14 if if IN cord-006870-f5w6fw6q 446 15 other other JJ cord-006870-f5w6fw6q 446 16 factors factor NNS cord-006870-f5w6fw6q 446 17 like like IN cord-006870-f5w6fw6q 446 18 initial initial JJ cord-006870-f5w6fw6q 446 19 GCS GCS NNP cord-006870-f5w6fw6q 446 20 have have VBP cord-006870-f5w6fw6q 446 21 an an DT cord-006870-f5w6fw6q 446 22 influence influence NN cord-006870-f5w6fw6q 446 23 too too RB cord-006870-f5w6fw6q 446 24 . . . cord-006870-f5w6fw6q 447 1 Methods method NNS cord-006870-f5w6fw6q 447 2 midline midline JJ cord-006870-f5w6fw6q 447 3 shift shift NN cord-006870-f5w6fw6q 447 4 , , , cord-006870-f5w6fw6q 447 5 if if IN cord-006870-f5w6fw6q 447 6 aSDH asdh JJ cord-006870-f5w6fw6q 447 7 was be VBD cord-006870-f5w6fw6q 447 8 surgically surgically RB cord-006870-f5w6fw6q 447 9 removed remove VBN cord-006870-f5w6fw6q 447 10 , , , cord-006870-f5w6fw6q 447 11 additional additional JJ cord-006870-f5w6fw6q 447 12 contusions contusion NNS cord-006870-f5w6fw6q 447 13 , , , cord-006870-f5w6fw6q 447 14 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 447 15 and and CC cord-006870-f5w6fw6q 447 16 intake intake NN cord-006870-f5w6fw6q 447 17 of of IN cord-006870-f5w6fw6q 447 18 anticoagulants anticoagulant NNS cord-006870-f5w6fw6q 447 19 . . . cord-006870-f5w6fw6q 448 1 Outcome outcome NN cord-006870-f5w6fw6q 448 2 was be VBD cord-006870-f5w6fw6q 448 3 analyzed analyze VBN cord-006870-f5w6fw6q 448 4 using use VBG cord-006870-f5w6fw6q 448 5 the the DT cord-006870-f5w6fw6q 448 6 Glasgow Glasgow NNP cord-006870-f5w6fw6q 448 7 Outcome outcome NN cord-006870-f5w6fw6q 448 8 Scale Scale NNP cord-006870-f5w6fw6q 448 9 ( ( -LRB- cord-006870-f5w6fw6q 448 10 GOS GOS NNP cord-006870-f5w6fw6q 448 11 ) ) -RRB- cord-006870-f5w6fw6q 448 12 at at IN cord-006870-f5w6fw6q 448 13 hospital hospital NN cord-006870-f5w6fw6q 448 14 discharge discharge NN cord-006870-f5w6fw6q 448 15 ( ( -LRB- cord-006870-f5w6fw6q 448 16 GOS GOS NNP cord-006870-f5w6fw6q 448 17 1 1 CD cord-006870-f5w6fw6q 448 18 ) ) -RRB- cord-006870-f5w6fw6q 448 19 and and CC cord-006870-f5w6fw6q 448 20 if if IN cord-006870-f5w6fw6q 448 21 possible possible JJ cord-006870-f5w6fw6q 448 22 6 6 CD cord-006870-f5w6fw6q 448 23 months month NNS cord-006870-f5w6fw6q 448 24 after after IN cord-006870-f5w6fw6q 448 25 discharge discharge NN cord-006870-f5w6fw6q 448 26 ( ( -LRB- cord-006870-f5w6fw6q 448 27 GOS GOS NNP cord-006870-f5w6fw6q 448 28 2 2 CD cord-006870-f5w6fw6q 448 29 ) ) -RRB- cord-006870-f5w6fw6q 448 30 . . . cord-006870-f5w6fw6q 449 1 Uni uni NN cord-006870-f5w6fw6q 449 2 - - HYPH cord-006870-f5w6fw6q 449 3 and and CC cord-006870-f5w6fw6q 449 4 multivariate multivariate JJ cord-006870-f5w6fw6q 449 5 analysis analysis NN cord-006870-f5w6fw6q 449 6 ( ( -LRB- cord-006870-f5w6fw6q 450 1 cox cox NNP cord-006870-f5w6fw6q 450 2 regression regression NN cord-006870-f5w6fw6q 450 3 model model NN cord-006870-f5w6fw6q 450 4 ) ) -RRB- cord-006870-f5w6fw6q 450 5 was be VBD cord-006870-f5w6fw6q 450 6 performed perform VBN cord-006870-f5w6fw6q 450 7 using use VBG cord-006870-f5w6fw6q 450 8 the the DT cord-006870-f5w6fw6q 450 9 Sigma Sigma NNP cord-006870-f5w6fw6q 450 10 Stat Stat NNP cord-006870-f5w6fw6q 450 11 Softwar Softwar NNP cord-006870-f5w6fw6q 450 12 0.05 0.05 CD cord-006870-f5w6fw6q 450 13 . . . cord-006870-f5w6fw6q 451 1 adverse adverse JJ cord-006870-f5w6fw6q 451 2 outcome outcome NN cord-006870-f5w6fw6q 451 3 p=0.014 p=0.014 NNS cord-006870-f5w6fw6q 451 4 . . . cord-006870-f5w6fw6q 452 1 In in IN cord-006870-f5w6fw6q 452 2 addition addition NN cord-006870-f5w6fw6q 452 3 , , , cord-006870-f5w6fw6q 452 4 all all DT cord-006870-f5w6fw6q 452 5 patients patient NNS cord-006870-f5w6fw6q 452 6 > > XX cord-006870-f5w6fw6q 452 7 65 65 CD cord-006870-f5w6fw6q 452 8 years year NNS cord-006870-f5w6fw6q 452 9 with with IN cord-006870-f5w6fw6q 452 10 an an DT cord-006870-f5w6fw6q 452 11 initial initial JJ cord-006870-f5w6fw6q 452 12 GCS GCS NNP cord-006870-f5w6fw6q 452 13 3 3 CD cord-006870-f5w6fw6q 452 14 died die VBD cord-006870-f5w6fw6q 452 15 whereas whereas IN cord-006870-f5w6fw6q 452 16 only only RB cord-006870-f5w6fw6q 452 17 44 44 CD cord-006870-f5w6fw6q 452 18 % % NN cord-006870-f5w6fw6q 452 19 of of IN cord-006870-f5w6fw6q 452 20 younger young JJR cord-006870-f5w6fw6q 452 21 patients patient NNS cord-006870-f5w6fw6q 452 22 with with IN cord-006870-f5w6fw6q 452 23 initial initial JJ cord-006870-f5w6fw6q 452 24 GCS GCS NNP cord-006870-f5w6fw6q 452 25 3 3 CD cord-006870-f5w6fw6q 452 26 died die VBD cord-006870-f5w6fw6q 452 27 ( ( -LRB- cord-006870-f5w6fw6q 452 28 p<0.005 p<0.005 JJ cord-006870-f5w6fw6q 452 29 ) ) -RRB- cord-006870-f5w6fw6q 452 30 . . . cord-006870-f5w6fw6q 453 1 This this DT cord-006870-f5w6fw6q 453 2 was be VBD cord-006870-f5w6fw6q 453 3 the the DT cord-006870-f5w6fw6q 453 4 only only JJ cord-006870-f5w6fw6q 453 5 significant significant JJ cord-006870-f5w6fw6q 453 6 result result NN cord-006870-f5w6fw6q 453 7 in in IN cord-006870-f5w6fw6q 453 8 the the DT cord-006870-f5w6fw6q 453 9 multivariate multivariate JJ cord-006870-f5w6fw6q 453 10 analysis analysis NN cord-006870-f5w6fw6q 454 1 The the DT cord-006870-f5w6fw6q 454 2 monovariate monovariate JJ cord-006870-f5w6fw6q 454 3 analysis analysis NN cord-006870-f5w6fw6q 454 4 of of IN cord-006870-f5w6fw6q 454 5 our -PRON- PRP$ cord-006870-f5w6fw6q 454 6 data datum NNS cord-006870-f5w6fw6q 454 7 showed show VBD cord-006870-f5w6fw6q 454 8 a a DT cord-006870-f5w6fw6q 454 9 significantly significantly RB cord-006870-f5w6fw6q 454 10 higher high JJR cord-006870-f5w6fw6q 454 11 risk risk NN cord-006870-f5w6fw6q 454 12 for for IN cord-006870-f5w6fw6q 454 13 adverse adverse JJ cord-006870-f5w6fw6q 454 14 outcome outcome NN cord-006870-f5w6fw6q 454 15 after after IN cord-006870-f5w6fw6q 454 16 aSDH asdh XX cord-006870-f5w6fw6q 455 1 whe whe UH cord-006870-f5w6fw6q 455 2 it -PRON- PRP cord-006870-f5w6fw6q 455 3 should should MD cord-006870-f5w6fw6q 455 4 be be VB cord-006870-f5w6fw6q 455 5 considered consider VBN cord-006870-f5w6fw6q 455 6 if if IN cord-006870-f5w6fw6q 455 7 it -PRON- PRP cord-006870-f5w6fw6q 455 8 is be VBZ cord-006870-f5w6fw6q 455 9 reasonable reasonable JJ cord-006870-f5w6fw6q 455 10 to to TO cord-006870-f5w6fw6q 455 11 transfer transfer VB cord-006870-f5w6fw6q 455 12 them -PRON- PRP cord-006870-f5w6fw6q 455 13 from from IN cord-006870-f5w6fw6q 455 14 local local JJ cord-006870-f5w6fw6q 455 15 hospitals hospital NNS cord-006870-f5w6fw6q 455 16 to to IN cord-006870-f5w6fw6q 455 17 a a DT cord-006870-f5w6fw6q 455 18 specialized specialized JJ cord-006870-f5w6fw6q 455 19 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 455 20 clinic clinic NN cord-006870-f5w6fw6q 455 21 , , , cord-006870-f5w6fw6q 455 22 especially especially RB cord-006870-f5w6fw6q 455 23 in in IN cord-006870-f5w6fw6q 455 24 times time NNS cord-006870-f5w6fw6q 455 25 of of IN cord-006870-f5w6fw6q 455 26 limited limited JJ cord-006870-f5w6fw6q 455 27 resources resource NNS cord-006870-f5w6fw6q 455 28 . . . cord-006870-f5w6fw6q 456 1 Reported report VBN cord-006870-f5w6fw6q 456 2 incidence incidence NN cord-006870-f5w6fw6q 456 3 of of IN cord-006870-f5w6fw6q 456 4 pulmonary pulmonary JJ cord-006870-f5w6fw6q 456 5 edema edema NN cord-006870-f5w6fw6q 456 6 in in IN cord-006870-f5w6fw6q 456 7 isolated isolate VBN cord-006870-f5w6fw6q 456 8 head head NN cord-006870-f5w6fw6q 456 9 injury injury NN cord-006870-f5w6fw6q 456 10 varies vary VBZ cord-006870-f5w6fw6q 456 11 from from IN cord-006870-f5w6fw6q 456 12 50 50 CD cord-006870-f5w6fw6q 456 13 - - SYM cord-006870-f5w6fw6q 456 14 85 85 CD cord-006870-f5w6fw6q 456 15 % % NN cord-006870-f5w6fw6q 456 16 . . . cord-006870-f5w6fw6q 457 1 Lung lung NN cord-006870-f5w6fw6q 457 2 sonography sonography NN cord-006870-f5w6fw6q 457 3 is be VBZ cord-006870-f5w6fw6q 457 4 a a DT cord-006870-f5w6fw6q 457 5 potentially potentially RB cord-006870-f5w6fw6q 457 6 useful useful JJ cord-006870-f5w6fw6q 457 7 non non AFX cord-006870-f5w6fw6q 457 8 invasive invasive JJ cord-006870-f5w6fw6q 457 9 technique technique NN cord-006870-f5w6fw6q 457 10 to to TO cord-006870-f5w6fw6q 457 11 detect detect VB cord-006870-f5w6fw6q 457 12 extravascular extravascular JJ cord-006870-f5w6fw6q 457 13 lung lung NN cord-006870-f5w6fw6q 457 14 water(EVLW water(EVLW NNPS cord-006870-f5w6fw6q 457 15 ) ) -RRB- cord-006870-f5w6fw6q 457 16 . . . cord-006870-f5w6fw6q 458 1 This this DT cord-006870-f5w6fw6q 458 2 study study NN cord-006870-f5w6fw6q 458 3 aimed aim VBD cord-006870-f5w6fw6q 458 4 to to TO cord-006870-f5w6fw6q 458 5 identify identify VB cord-006870-f5w6fw6q 458 6 the the DT cord-006870-f5w6fw6q 458 7 presence presence NN cord-006870-f5w6fw6q 458 8 of of IN cord-006870-f5w6fw6q 458 9 EVLW EVLW NNS cord-006870-f5w6fw6q 458 10 using use VBG cord-006870-f5w6fw6q 458 11 lung lung NN cord-006870-f5w6fw6q 458 12 ultrasound ultrasound NN cord-006870-f5w6fw6q 458 13 ( ( -LRB- cord-006870-f5w6fw6q 458 14 B b NN cord-006870-f5w6fw6q 458 15 lines line NNS cord-006870-f5w6fw6q 458 16 > > XX cord-006870-f5w6fw6q 458 17 3 3 CD cord-006870-f5w6fw6q 458 18 per per IN cord-006870-f5w6fw6q 458 19 lung lung NN cord-006870-f5w6fw6q 458 20 field field NN cord-006870-f5w6fw6q 458 21 ) ) -RRB- cord-006870-f5w6fw6q 458 22 in in IN cord-006870-f5w6fw6q 458 23 chead chead NN cord-006870-f5w6fw6q 458 24 injured injure VBN cord-006870-f5w6fw6q 458 25 patients patient NNS cord-006870-f5w6fw6q 458 26 admitted admit VBN cord-006870-f5w6fw6q 458 27 to to IN cord-006870-f5w6fw6q 458 28 ICU ICU NNP cord-006870-f5w6fw6q 458 29 . . . cord-006870-f5w6fw6q 459 1 Secondary secondary JJ cord-006870-f5w6fw6q 459 2 objectives objective NNS cord-006870-f5w6fw6q 459 3 were be VBD cord-006870-f5w6fw6q 459 4 to to TO cord-006870-f5w6fw6q 459 5 compare compare VB cord-006870-f5w6fw6q 459 6 diagnostic diagnostic JJ cord-006870-f5w6fw6q 459 7 accuracy accuracy NN cord-006870-f5w6fw6q 459 8 and and CC cord-006870-f5w6fw6q 459 9 time time NN cord-006870-f5w6fw6q 459 10 to to IN cord-006870-f5w6fw6q 459 11 identification identification NN cord-006870-f5w6fw6q 459 12 of of IN cord-006870-f5w6fw6q 459 13 EVLW EVLW NNS cord-006870-f5w6fw6q 459 14 using use VBG cord-006870-f5w6fw6q 459 15 chest chest NN cord-006870-f5w6fw6q 459 16 x x NN cord-006870-f5w6fw6q 459 17 ray ray NN cord-006870-f5w6fw6q 459 18 versus versus IN cord-006870-f5w6fw6q 459 19 lung lung NN cord-006870-f5w6fw6q 459 20 ultrasound ultrasound NN cord-006870-f5w6fw6q 459 21 . . . cord-006870-f5w6fw6q 460 1 Association Association NNP cord-006870-f5w6fw6q 460 2 of of IN cord-006870-f5w6fw6q 460 3 EVLW EVLW NNP cord-006870-f5w6fw6q 460 4 with with IN cord-006870-f5w6fw6q 460 5 duration duration NN cord-006870-f5w6fw6q 460 6 of of IN cord-006870-f5w6fw6q 460 7 mechanical mechanical JJ cord-006870-f5w6fw6q 460 8 ventilation ventilation NN cord-006870-f5w6fw6q 461 1 ( ( -LRB- cord-006870-f5w6fw6q 461 2 MV)and mv)and NN cord-006870-f5w6fw6q 461 3 ICU ICU NNP cord-006870-f5w6fw6q 461 4 stay stay NN cord-006870-f5w6fw6q 461 5 were be VBD cord-006870-f5w6fw6q 461 6 observed observe VBN cord-006870-f5w6fw6q 461 7 After after IN cord-006870-f5w6fw6q 461 8 Ethical ethical JJ cord-006870-f5w6fw6q 461 9 clearance clearance NN cord-006870-f5w6fw6q 461 10 ( ( -LRB- cord-006870-f5w6fw6q 461 11 IEC IEC NNP cord-006870-f5w6fw6q 461 12 No No NNP cord-006870-f5w6fw6q 461 13 . . . cord-006870-f5w6fw6q 461 14 INT int NN cord-006870-f5w6fw6q 461 15 / / SYM cord-006870-f5w6fw6q 461 16 IEC/2015/372 iec/2015/372 NN cord-006870-f5w6fw6q 461 17 ) ) -RRB- cord-006870-f5w6fw6q 461 18 , , , cord-006870-f5w6fw6q 461 19 120 120 CD cord-006870-f5w6fw6q 461 20 patients patient NNS cord-006870-f5w6fw6q 461 21 with with IN cord-006870-f5w6fw6q 461 22 head head NN cord-006870-f5w6fw6q 461 23 injury injury NN cord-006870-f5w6fw6q 461 24 requiring require VBG cord-006870-f5w6fw6q 461 25 MV MV NNP cord-006870-f5w6fw6q 461 26 and and CC cord-006870-f5w6fw6q 461 27 critical critical JJ cord-006870-f5w6fw6q 461 28 care care NN cord-006870-f5w6fw6q 461 29 were be VBD cord-006870-f5w6fw6q 461 30 enrolled enrol VBN cord-006870-f5w6fw6q 461 31 in in IN cord-006870-f5w6fw6q 461 32 the the DT cord-006870-f5w6fw6q 461 33 study study NN cord-006870-f5w6fw6q 461 34 . . . cord-006870-f5w6fw6q 462 1 Daily daily JJ cord-006870-f5w6fw6q 462 2 routine routine JJ cord-006870-f5w6fw6q 462 3 chest chest NN cord-006870-f5w6fw6q 462 4 x x NN cord-006870-f5w6fw6q 462 5 ray ray NN cord-006870-f5w6fw6q 462 6 and and CC cord-006870-f5w6fw6q 462 7 bedside bedside NN cord-006870-f5w6fw6q 462 8 lung lung NN cord-006870-f5w6fw6q 462 9 ultrasound ultrasound NN cord-006870-f5w6fw6q 462 10 were be VBD cord-006870-f5w6fw6q 462 11 done do VBN cord-006870-f5w6fw6q 462 12 from from IN cord-006870-f5w6fw6q 462 13 the the DT cord-006870-f5w6fw6q 462 14 day day NN cord-006870-f5w6fw6q 462 15 of of IN cord-006870-f5w6fw6q 462 16 ICU ICU NNP cord-006870-f5w6fw6q 462 17 admission admission NN cord-006870-f5w6fw6q 462 18 until until IN cord-006870-f5w6fw6q 462 19 the the DT cord-006870-f5w6fw6q 462 20 patient patient NN cord-006870-f5w6fw6q 462 21 was be VBD cord-006870-f5w6fw6q 462 22 on on IN cord-006870-f5w6fw6q 462 23 mechanical mechanical JJ cord-006870-f5w6fw6q 462 24 ventilator ventilator NN cord-006870-f5w6fw6q 462 25 support support NN cord-006870-f5w6fw6q 462 26 . . . cord-006870-f5w6fw6q 463 1 Four four CD cord-006870-f5w6fw6q 463 2 inter inter JJ cord-006870-f5w6fw6q 463 3 costal costal JJ cord-006870-f5w6fw6q 463 4 spaces space NNS cord-006870-f5w6fw6q 463 5 ( ( -LRB- cord-006870-f5w6fw6q 463 6 ICS ICS NNP cord-006870-f5w6fw6q 463 7 ) ) -RRB- cord-006870-f5w6fw6q 463 8 were be VBD cord-006870-f5w6fw6q 463 9 scanned scan VBN cord-006870-f5w6fw6q 463 10 in in IN cord-006870-f5w6fw6q 463 11 semi semi JJ cord-006870-f5w6fw6q 463 12 recumbent recumbent JJ cord-006870-f5w6fw6q 463 13 position position NN cord-006870-f5w6fw6q 463 14 ; ; : cord-006870-f5w6fw6q 463 15 third third JJ cord-006870-f5w6fw6q 463 16 and and CC cord-006870-f5w6fw6q 463 17 sixth sixth JJ cord-006870-f5w6fw6q 463 18 ICS ICS NNP cord-006870-f5w6fw6q 463 19 on on IN cord-006870-f5w6fw6q 463 20 either either DT cord-006870-f5w6fw6q 463 21 side side NN cord-006870-f5w6fw6q 463 22 of of IN cord-006870-f5w6fw6q 463 23 sternum sternum NN cord-006870-f5w6fw6q 463 24 till till IN cord-006870-f5w6fw6q 463 25 mid mid JJ cord-006870-f5w6fw6q 463 26 clavicular clavicular JJ cord-006870-f5w6fw6q 463 27 line line NN cord-006870-f5w6fw6q 463 28 . . . cord-006870-f5w6fw6q 464 1 EVLW EVLW NNS cord-006870-f5w6fw6q 464 2 was be VBD cord-006870-f5w6fw6q 464 3 reprted reprte VBN cord-006870-f5w6fw6q 464 4 as as IN cord-006870-f5w6fw6q 464 5 > > XX cord-006870-f5w6fw6q 464 6 3 3 CD cord-006870-f5w6fw6q 464 7 B b NN cord-006870-f5w6fw6q 464 8 lines line NNS cord-006870-f5w6fw6q 464 9 per per IN cord-006870-f5w6fw6q 464 10 lung lung NN cord-006870-f5w6fw6q 464 11 field field NN cord-006870-f5w6fw6q 464 12 scan scan JJ cord-006870-f5w6fw6q 464 13 sonographically sonographically RB cord-006870-f5w6fw6q 464 14 . . . cord-006870-f5w6fw6q 465 1 Details detail NNS cord-006870-f5w6fw6q 465 2 of of IN cord-006870-f5w6fw6q 465 3 MV MV NNP cord-006870-f5w6fw6q 465 4 and and CC cord-006870-f5w6fw6q 465 5 ICU ICU NNP cord-006870-f5w6fw6q 465 6 management management NN cord-006870-f5w6fw6q 465 7 were be VBD cord-006870-f5w6fw6q 465 8 noted note VBN cord-006870-f5w6fw6q 465 9 . . . cord-006870-f5w6fw6q 466 1 Evidence evidence NN cord-006870-f5w6fw6q 466 2 of of IN cord-006870-f5w6fw6q 466 3 EVLW EVLW NNS cord-006870-f5w6fw6q 466 4 at at IN cord-006870-f5w6fw6q 466 5 the the DT cord-006870-f5w6fw6q 466 6 time time NN cord-006870-f5w6fw6q 466 7 of of IN cord-006870-f5w6fw6q 466 8 admission admission NN cord-006870-f5w6fw6q 466 9 using use VBG cord-006870-f5w6fw6q 466 10 sonography sonography NN cord-006870-f5w6fw6q 466 11 and and CC cord-006870-f5w6fw6q 466 12 CXR CXR NNP cord-006870-f5w6fw6q 466 13 was be VBD cord-006870-f5w6fw6q 466 14 recorded record VBN cord-006870-f5w6fw6q 466 15 in in IN cord-006870-f5w6fw6q 466 16 32 32 CD cord-006870-f5w6fw6q 466 17 and and CC cord-006870-f5w6fw6q 466 18 6 6 CD cord-006870-f5w6fw6q 466 19 patients patient NNS cord-006870-f5w6fw6q 466 20 respectively respectively RB cord-006870-f5w6fw6q 466 21 . . . cord-006870-f5w6fw6q 467 1 During during IN cord-006870-f5w6fw6q 467 2 ICU ICU NNP cord-006870-f5w6fw6q 467 3 stay stay VBP cord-006870-f5w6fw6q 467 4 61.7 61.7 CD cord-006870-f5w6fw6q 467 5 % % NN cord-006870-f5w6fw6q 467 6 patients patient NNS cord-006870-f5w6fw6q 467 7 showed show VBD cord-006870-f5w6fw6q 467 8 EVLW EVLW NNS cord-006870-f5w6fw6q 467 9 using use VBG cord-006870-f5w6fw6q 467 10 lung lung NN cord-006870-f5w6fw6q 467 11 USG USG NNP cord-006870-f5w6fw6q 467 12 ( ( -LRB- cord-006870-f5w6fw6q 467 13 vs vs IN cord-006870-f5w6fw6q 467 14 43 43 CD cord-006870-f5w6fw6q 467 15 patients patient NNS cord-006870-f5w6fw6q 467 16 on on IN cord-006870-f5w6fw6q 467 17 CXR CXR NNP cord-006870-f5w6fw6q 467 18 ) ) -RRB- cord-006870-f5w6fw6q 467 19 . . . cord-006870-f5w6fw6q 468 1 Mean mean JJ cord-006870-f5w6fw6q 468 2 delay delay NN cord-006870-f5w6fw6q 468 3 in in IN cord-006870-f5w6fw6q 468 4 detection detection NN cord-006870-f5w6fw6q 468 5 of of IN cord-006870-f5w6fw6q 468 6 EVLW EVLW NNS cord-006870-f5w6fw6q 468 7 on on IN cord-006870-f5w6fw6q 468 8 CXR CXR NNP cord-006870-f5w6fw6q 468 9 after after IN cord-006870-f5w6fw6q 468 10 detection detection NN cord-006870-f5w6fw6q 468 11 on on IN cord-006870-f5w6fw6q 468 12 ultrasound ultrasound NN cord-006870-f5w6fw6q 468 13 was be VBD cord-006870-f5w6fw6q 468 14 1.42±0.767 1.42±0.767 JJ cord-006870-f5w6fw6q 468 15 days day NNS cord-006870-f5w6fw6q 468 16 . . . cord-006870-f5w6fw6q 469 1 Patients patient NNS cord-006870-f5w6fw6q 469 2 with with IN cord-006870-f5w6fw6q 469 3 low low JJ cord-006870-f5w6fw6q 469 4 GCS GCS NNP cord-006870-f5w6fw6q 469 5 , , , cord-006870-f5w6fw6q 469 6 S. S. NNP cord-006870-f5w6fw6q 469 7 Albumin Albumin NNP cord-006870-f5w6fw6q 469 8 , , , cord-006870-f5w6fw6q 469 9 Pao2 Pao2 NNP cord-006870-f5w6fw6q 469 10 / / SYM cord-006870-f5w6fw6q 469 11 Fio2 Fio2 NNP cord-006870-f5w6fw6q 469 12 ratio ratio NN cord-006870-f5w6fw6q 469 13 and and CC cord-006870-f5w6fw6q 469 14 greater great JJR cord-006870-f5w6fw6q 469 15 APACHE APACHE NNP cord-006870-f5w6fw6q 469 16 II II NNP cord-006870-f5w6fw6q 469 17 and and CC cord-006870-f5w6fw6q 469 18 SAPS SAPS NNP cord-006870-f5w6fw6q 469 19 II II NNP cord-006870-f5w6fw6q 469 20 had have VBD cord-006870-f5w6fw6q 469 21 significantly significantly RB cord-006870-f5w6fw6q 469 22 higher high JJR cord-006870-f5w6fw6q 469 23 incidence incidence NN cord-006870-f5w6fw6q 469 24 of of IN cord-006870-f5w6fw6q 469 25 EVLW EVLW NNS cord-006870-f5w6fw6q 469 26 . . . cord-006870-f5w6fw6q 470 1 Duration duration NN cord-006870-f5w6fw6q 470 2 of of IN cord-006870-f5w6fw6q 470 3 weaning weaning NN cord-006870-f5w6fw6q 470 4 , , , cord-006870-f5w6fw6q 470 5 mechanical mechanical JJ cord-006870-f5w6fw6q 470 6 ventilation ventilation NN cord-006870-f5w6fw6q 470 7 and and CC cord-006870-f5w6fw6q 470 8 ICU ICU NNP cord-006870-f5w6fw6q 470 9 stay stay NN cord-006870-f5w6fw6q 470 10 was be VBD cord-006870-f5w6fw6q 470 11 significantly significantly RB cord-006870-f5w6fw6q 470 12 longer long RBR cord-006870-f5w6fw6q 470 13 in in IN cord-006870-f5w6fw6q 470 14 patients patient NNS cord-006870-f5w6fw6q 470 15 with with IN cord-006870-f5w6fw6q 470 16 presence presence NN cord-006870-f5w6fw6q 470 17 of of IN cord-006870-f5w6fw6q 470 18 EVLW EVLW NNS cord-006870-f5w6fw6q 470 19 ( ( -LRB- cord-006870-f5w6fw6q 470 20 p p NN cord-006870-f5w6fw6q 470 21 < < XX cord-006870-f5w6fw6q 470 22 0.05 0.05 CD cord-006870-f5w6fw6q 470 23 ) ) -RRB- cord-006870-f5w6fw6q 471 1 Conclusions conclusion NNS cord-006870-f5w6fw6q 471 2 : : : cord-006870-f5w6fw6q 472 1 Lung lung NN cord-006870-f5w6fw6q 472 2 ultrasound ultrasound NN cord-006870-f5w6fw6q 472 3 appears appear VBZ cord-006870-f5w6fw6q 472 4 promising promise VBG cord-006870-f5w6fw6q 472 5 in in IN cord-006870-f5w6fw6q 472 6 detecting detect VBG cord-006870-f5w6fw6q 472 7 EVLW EVLW NNS cord-006870-f5w6fw6q 472 8 earlier early RBR cord-006870-f5w6fw6q 472 9 than than IN cord-006870-f5w6fw6q 472 10 chest chest NN cord-006870-f5w6fw6q 472 11 X x NN cord-006870-f5w6fw6q 472 12 ray ray NN cord-006870-f5w6fw6q 472 13 and and CC cord-006870-f5w6fw6q 472 14 may may MD cord-006870-f5w6fw6q 472 15 aid aid VB cord-006870-f5w6fw6q 472 16 to to TO cord-006870-f5w6fw6q 472 17 minimize minimize VB cord-006870-f5w6fw6q 472 18 the the DT cord-006870-f5w6fw6q 472 19 duration duration NN cord-006870-f5w6fw6q 472 20 of of IN cord-006870-f5w6fw6q 472 21 mechanical mechanical JJ cord-006870-f5w6fw6q 472 22 ventilation ventilation NN cord-006870-f5w6fw6q 472 23 , , , cord-006870-f5w6fw6q 472 24 weaning weaning NN cord-006870-f5w6fw6q 472 25 and and CC cord-006870-f5w6fw6q 472 26 ICU ICU NNP cord-006870-f5w6fw6q 472 27 stay stay VBP cord-006870-f5w6fw6q 472 28 . . . cord-006870-f5w6fw6q 473 1 Antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 473 2 drugs drug NNS cord-006870-f5w6fw6q 473 3 ( ( -LRB- cord-006870-f5w6fw6q 473 4 AEDs aed NNS cord-006870-f5w6fw6q 473 5 ) ) -RRB- cord-006870-f5w6fw6q 473 6 are be VBP cord-006870-f5w6fw6q 473 7 recommended recommend VBN cord-006870-f5w6fw6q 473 8 by by IN cord-006870-f5w6fw6q 473 9 guidelines guideline NNS cord-006870-f5w6fw6q 473 10 for for IN cord-006870-f5w6fw6q 473 11 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 473 12 of of IN cord-006870-f5w6fw6q 473 13 early early JJ cord-006870-f5w6fw6q 473 14 post post JJ cord-006870-f5w6fw6q 473 15 - - JJ cord-006870-f5w6fw6q 473 16 traumatic traumatic JJ cord-006870-f5w6fw6q 473 17 seizures seizure NNS cord-006870-f5w6fw6q 473 18 ( ( -LRB- cord-006870-f5w6fw6q 473 19 PTS PTS NNP cord-006870-f5w6fw6q 473 20 ) ) -RRB- cord-006870-f5w6fw6q 473 21 associated associate VBN cord-006870-f5w6fw6q 473 22 with with IN cord-006870-f5w6fw6q 473 23 traumatic traumatic JJ cord-006870-f5w6fw6q 473 24 brain brain NN cord-006870-f5w6fw6q 473 25 injury injury NN cord-006870-f5w6fw6q 473 26 ( ( -LRB- cord-006870-f5w6fw6q 473 27 TBI TBI NNP cord-006870-f5w6fw6q 473 28 ) ) -RRB- cord-006870-f5w6fw6q 473 29 . . . cord-006870-f5w6fw6q 474 1 There there EX cord-006870-f5w6fw6q 474 2 has have VBZ cord-006870-f5w6fw6q 474 3 been be VBN cord-006870-f5w6fw6q 474 4 an an DT cord-006870-f5w6fw6q 474 5 increased increase VBN cord-006870-f5w6fw6q 474 6 use use NN cord-006870-f5w6fw6q 474 7 of of IN cord-006870-f5w6fw6q 474 8 both both CC cord-006870-f5w6fw6q 474 9 phenytoin phenytoin JJ cord-006870-f5w6fw6q 474 10 and and CC cord-006870-f5w6fw6q 474 11 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 474 12 for for IN cord-006870-f5w6fw6q 474 13 this this DT cord-006870-f5w6fw6q 474 14 indication indication NN cord-006870-f5w6fw6q 474 15 . . . cord-006870-f5w6fw6q 475 1 The the DT cord-006870-f5w6fw6q 475 2 purpose purpose NN cord-006870-f5w6fw6q 475 3 of of IN cord-006870-f5w6fw6q 475 4 this this DT cord-006870-f5w6fw6q 475 5 study study NN cord-006870-f5w6fw6q 475 6 is be VBZ cord-006870-f5w6fw6q 475 7 to to TO cord-006870-f5w6fw6q 475 8 determine determine VB cord-006870-f5w6fw6q 475 9 the the DT cord-006870-f5w6fw6q 475 10 incremental incremental JJ cord-006870-f5w6fw6q 475 11 cost cost NN cord-006870-f5w6fw6q 475 12 - - HYPH cord-006870-f5w6fw6q 475 13 effectiveness effectiveness NN cord-006870-f5w6fw6q 475 14 of of IN cord-006870-f5w6fw6q 475 15 phenytoin phenytoin NN cord-006870-f5w6fw6q 475 16 compared compare VBN cord-006870-f5w6fw6q 475 17 with with IN cord-006870-f5w6fw6q 475 18 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 475 19 for for IN cord-006870-f5w6fw6q 475 20 early early JJ cord-006870-f5w6fw6q 475 21 PTS PTS NNP cord-006870-f5w6fw6q 475 22 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 475 23 in in IN cord-006870-f5w6fw6q 475 24 TBI TBI NNP cord-006870-f5w6fw6q 475 25 patients patient NNS cord-006870-f5w6fw6q 475 26 . . . cord-006870-f5w6fw6q 476 1 A a DT cord-006870-f5w6fw6q 476 2 cost cost NN cord-006870-f5w6fw6q 476 3 - - HYPH cord-006870-f5w6fw6q 476 4 effectiveness effectiveness NN cord-006870-f5w6fw6q 476 5 study study NN cord-006870-f5w6fw6q 476 6 was be VBD cord-006870-f5w6fw6q 476 7 conducted conduct VBN cord-006870-f5w6fw6q 476 8 comparing compare VBG cord-006870-f5w6fw6q 476 9 phenytoin phenytoin NN cord-006870-f5w6fw6q 476 10 and and CC cord-006870-f5w6fw6q 476 11 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 476 12 for for IN cord-006870-f5w6fw6q 476 13 early early JJ cord-006870-f5w6fw6q 476 14 PTS PTS NNP cord-006870-f5w6fw6q 476 15 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 476 16 during during IN cord-006870-f5w6fw6q 476 17 the the DT cord-006870-f5w6fw6q 476 18 7 7 CD cord-006870-f5w6fw6q 476 19 days day NNS cord-006870-f5w6fw6q 476 20 post post JJ cord-006870-f5w6fw6q 476 21 - - JJ cord-006870-f5w6fw6q 476 22 TBI tbi NN cord-006870-f5w6fw6q 476 23 . . . cord-006870-f5w6fw6q 477 1 Patients patient NNS cord-006870-f5w6fw6q 477 2 were be VBD cord-006870-f5w6fw6q 477 3 included include VBN cord-006870-f5w6fw6q 477 4 if if IN cord-006870-f5w6fw6q 477 5 they -PRON- PRP cord-006870-f5w6fw6q 477 6 were be VBD cord-006870-f5w6fw6q 477 7 18 18 CD cord-006870-f5w6fw6q 477 8 years year NNS cord-006870-f5w6fw6q 477 9 or or CC cord-006870-f5w6fw6q 477 10 older old JJR cord-006870-f5w6fw6q 477 11 , , , cord-006870-f5w6fw6q 477 12 received receive VBD cord-006870-f5w6fw6q 477 13 a a DT cord-006870-f5w6fw6q 477 14 study study NN cord-006870-f5w6fw6q 477 15 drug drug NN cord-006870-f5w6fw6q 477 16 , , , cord-006870-f5w6fw6q 477 17 and and CC cord-006870-f5w6fw6q 477 18 had have VBD cord-006870-f5w6fw6q 477 19 a a DT cord-006870-f5w6fw6q 477 20 diagnosis diagnosis NN cord-006870-f5w6fw6q 477 21 of of IN cord-006870-f5w6fw6q 477 22 TBI TBI NNP cord-006870-f5w6fw6q 477 23 . . . cord-006870-f5w6fw6q 478 1 Patients patient NNS cord-006870-f5w6fw6q 478 2 were be VBD cord-006870-f5w6fw6q 478 3 excluded exclude VBN cord-006870-f5w6fw6q 478 4 if if IN cord-006870-f5w6fw6q 478 5 they -PRON- PRP cord-006870-f5w6fw6q 478 6 had have VBD cord-006870-f5w6fw6q 478 7 a a DT cord-006870-f5w6fw6q 478 8 history history NN cord-006870-f5w6fw6q 478 9 of of IN cord-006870-f5w6fw6q 478 10 epilepsy epilepsy NN cord-006870-f5w6fw6q 478 11 , , , cord-006870-f5w6fw6q 478 12 did do VBD cord-006870-f5w6fw6q 478 13 not not RB cord-006870-f5w6fw6q 478 14 sustain sustain VB cord-006870-f5w6fw6q 478 15 a a DT cord-006870-f5w6fw6q 478 16 recent recent JJ cord-006870-f5w6fw6q 478 17 TBI TBI NNP cord-006870-f5w6fw6q 478 18 , , , cord-006870-f5w6fw6q 478 19 were be VBD cord-006870-f5w6fw6q 478 20 initiated initiate VBN cord-006870-f5w6fw6q 478 21 on on IN cord-006870-f5w6fw6q 478 22 both both DT cord-006870-f5w6fw6q 478 23 study study NN cord-006870-f5w6fw6q 478 24 drugs drug NNS cord-006870-f5w6fw6q 478 25 concurrently concurrently RB cord-006870-f5w6fw6q 478 26 , , , cord-006870-f5w6fw6q 478 27 or or CC cord-006870-f5w6fw6q 478 28 were be VBD cord-006870-f5w6fw6q 478 29 switched switch VBN cord-006870-f5w6fw6q 478 30 to to IN cord-006870-f5w6fw6q 478 31 pentobarbital pentobarbital VB cord-006870-f5w6fw6q 478 32 for for IN cord-006870-f5w6fw6q 478 33 elevated elevated JJ cord-006870-f5w6fw6q 478 34 intracranial intracranial JJ cord-006870-f5w6fw6q 478 35 pressure pressure NN cord-006870-f5w6fw6q 478 36 . . . cord-006870-f5w6fw6q 479 1 Data datum NNS cord-006870-f5w6fw6q 479 2 was be VBD cord-006870-f5w6fw6q 479 3 collected collect VBN cord-006870-f5w6fw6q 479 4 via via IN cord-006870-f5w6fw6q 479 5 retrospective retrospective JJ cord-006870-f5w6fw6q 479 6 chart chart NN cord-006870-f5w6fw6q 479 7 review review NN cord-006870-f5w6fw6q 479 8 using use VBG cord-006870-f5w6fw6q 479 9 electronic electronic JJ cord-006870-f5w6fw6q 479 10 medical medical JJ cord-006870-f5w6fw6q 479 11 records record NNS cord-006870-f5w6fw6q 479 12 and and CC cord-006870-f5w6fw6q 479 13 publically publically RB cord-006870-f5w6fw6q 479 14 reported report VBD cord-006870-f5w6fw6q 479 15 costs cost NNS cord-006870-f5w6fw6q 479 16 . . . cord-006870-f5w6fw6q 480 1 Effectiveness Effectiveness NNP cord-006870-f5w6fw6q 480 2 was be VBD cord-006870-f5w6fw6q 480 3 measured measure VBN cord-006870-f5w6fw6q 480 4 as as IN cord-006870-f5w6fw6q 480 5 having have VBG cord-006870-f5w6fw6q 480 6 a a DT cord-006870-f5w6fw6q 480 7 successful successful JJ cord-006870-f5w6fw6q 480 8 seizure seizure NN cord-006870-f5w6fw6q 480 9 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 480 10 regimen regimen NN cord-006870-f5w6fw6q 480 11 ( ( -LRB- cord-006870-f5w6fw6q 480 12 SSPR SSPR NNP cord-006870-f5w6fw6q 480 13 ) ) -RRB- cord-006870-f5w6fw6q 480 14 , , , cord-006870-f5w6fw6q 480 15 which which WDT cord-006870-f5w6fw6q 480 16 was be VBD cord-006870-f5w6fw6q 480 17 defined define VBN cord-006870-f5w6fw6q 480 18 as as IN cord-006870-f5w6fw6q 480 19 1 1 CD cord-006870-f5w6fw6q 480 20 ) ) -RRB- cord-006870-f5w6fw6q 480 21 no no DT cord-006870-f5w6fw6q 480 22 clinical clinical JJ cord-006870-f5w6fw6q 480 23 or or CC cord-006870-f5w6fw6q 480 24 electrographic electrographic JJ cord-006870-f5w6fw6q 480 25 seizure seizure NN cord-006870-f5w6fw6q 480 26 , , , cord-006870-f5w6fw6q 480 27 2 2 CD cord-006870-f5w6fw6q 480 28 ) ) -RRB- cord-006870-f5w6fw6q 481 1 no no DT cord-006870-f5w6fw6q 481 2 discontinuation discontinuation NN cord-006870-f5w6fw6q 481 3 of of IN cord-006870-f5w6fw6q 481 4 study study NN cord-006870-f5w6fw6q 481 5 AED AED NNP cord-006870-f5w6fw6q 481 6 , , , cord-006870-f5w6fw6q 481 7 3 3 CD cord-006870-f5w6fw6q 481 8 ) ) -RRB- cord-006870-f5w6fw6q 481 9 no no DT cord-006870-f5w6fw6q 481 10 cross cross NN cord-006870-f5w6fw6q 481 11 - - HYPH cord-006870-f5w6fw6q 481 12 over over NN cord-006870-f5w6fw6q 481 13 of of IN cord-006870-f5w6fw6q 481 14 study study NN cord-006870-f5w6fw6q 481 15 AED AED NNP cord-006870-f5w6fw6q 481 16 to to IN cord-006870-f5w6fw6q 481 17 different different JJ cord-006870-f5w6fw6q 481 18 AED AED NNP cord-006870-f5w6fw6q 481 19 , , , cord-006870-f5w6fw6q 481 20 or or CC cord-006870-f5w6fw6q 481 21 4 4 CD cord-006870-f5w6fw6q 481 22 ) ) -RRB- cord-006870-f5w6fw6q 482 1 no no DT cord-006870-f5w6fw6q 482 2 addition addition NN cord-006870-f5w6fw6q 482 3 of of IN cord-006870-f5w6fw6q 482 4 AED AED NNP cord-006870-f5w6fw6q 482 5 during during IN cord-006870-f5w6fw6q 482 6 the the DT cord-006870-f5w6fw6q 482 7 7 7 CD cord-006870-f5w6fw6q 482 8 days day NNS cord-006870-f5w6fw6q 482 9 of of IN cord-006870-f5w6fw6q 482 10 therapy therapy NN cord-006870-f5w6fw6q 482 11 . . . cord-006870-f5w6fw6q 483 1 The the DT cord-006870-f5w6fw6q 483 2 costs cost NNS cord-006870-f5w6fw6q 483 3 included include VBD cord-006870-f5w6fw6q 483 4 costs cost NNS cord-006870-f5w6fw6q 483 5 of of IN cord-006870-f5w6fw6q 483 6 the the DT cord-006870-f5w6fw6q 483 7 study study NN cord-006870-f5w6fw6q 483 8 drugs drug NNS cord-006870-f5w6fw6q 483 9 , , , cord-006870-f5w6fw6q 483 10 phenytoin phenytoin JJ cord-006870-f5w6fw6q 483 11 level level NN cord-006870-f5w6fw6q 483 12 , , , cord-006870-f5w6fw6q 483 13 and and CC cord-006870-f5w6fw6q 483 14 EEG EEG NNP cord-006870-f5w6fw6q 483 15 . . . cord-006870-f5w6fw6q 484 1 The the DT cord-006870-f5w6fw6q 484 2 data datum NNS cord-006870-f5w6fw6q 484 3 was be VBD cord-006870-f5w6fw6q 484 4 used use VBN cord-006870-f5w6fw6q 484 5 to to TO cord-006870-f5w6fw6q 484 6 calculate calculate VB cord-006870-f5w6fw6q 484 7 the the DT cord-006870-f5w6fw6q 484 8 primary primary JJ cord-006870-f5w6fw6q 484 9 endpoint endpoint NN cord-006870-f5w6fw6q 484 10 , , , cord-006870-f5w6fw6q 484 11 the the DT cord-006870-f5w6fw6q 484 12 incremental incremental JJ cord-006870-f5w6fw6q 484 13 cost cost NN cord-006870-f5w6fw6q 484 14 for for IN cord-006870-f5w6fw6q 484 15 the the DT cord-006870-f5w6fw6q 484 16 incremental incremental JJ cord-006870-f5w6fw6q 484 17 change change NN cord-006870-f5w6fw6q 484 18 in in IN cord-006870-f5w6fw6q 484 19 SSPR SSPR NNP cord-006870-f5w6fw6q 484 20 or or CC cord-006870-f5w6fw6q 484 21 the the DT cord-006870-f5w6fw6q 484 22 incremental incremental JJ cord-006870-f5w6fw6q 484 23 cost cost NN cord-006870-f5w6fw6q 484 24 effectiveness effectiveness NN cord-006870-f5w6fw6q 484 25 ratio ratio NN cord-006870-f5w6fw6q 484 26 ( ( -LRB- cord-006870-f5w6fw6q 484 27 ICER ICER NNP cord-006870-f5w6fw6q 484 28 ) ) -RRB- cord-006870-f5w6fw6q 484 29 . . . cord-006870-f5w6fw6q 485 1 The the DT cord-006870-f5w6fw6q 485 2 phenytoin phenytoin JJ cord-006870-f5w6fw6q 485 3 regimen regimen NN cord-006870-f5w6fw6q 485 4 ( ( -LRB- cord-006870-f5w6fw6q 485 5 n=136 n=136 NFP cord-006870-f5w6fw6q 485 6 ) ) -RRB- cord-006870-f5w6fw6q 485 7 cost cost VB cord-006870-f5w6fw6q 485 8 $ $ $ cord-006870-f5w6fw6q 485 9 371.76 371.76 CD cord-006870-f5w6fw6q 485 10 and and CC cord-006870-f5w6fw6q 485 11 had have VBD cord-006870-f5w6fw6q 485 12 an an DT cord-006870-f5w6fw6q 485 13 SSPR SSPR NNP cord-006870-f5w6fw6q 485 14 of of IN cord-006870-f5w6fw6q 485 15 81.6 81.6 CD cord-006870-f5w6fw6q 485 16 % % NN cord-006870-f5w6fw6q 485 17 . . . cord-006870-f5w6fw6q 486 1 The the DT cord-006870-f5w6fw6q 486 2 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 486 3 regimen regimen NN cord-006870-f5w6fw6q 486 4 ( ( -LRB- cord-006870-f5w6fw6q 486 5 n=237 n=237 NNP cord-006870-f5w6fw6q 486 6 ) ) -RRB- cord-006870-f5w6fw6q 486 7 cost cost VB cord-006870-f5w6fw6q 486 8 $ $ $ cord-006870-f5w6fw6q 486 9 628.85 628.85 CD cord-006870-f5w6fw6q 486 10 and and CC cord-006870-f5w6fw6q 486 11 had have VBD cord-006870-f5w6fw6q 486 12 an an DT cord-006870-f5w6fw6q 486 13 SSPR SSPR NNP cord-006870-f5w6fw6q 486 14 of of IN cord-006870-f5w6fw6q 486 15 86.1 86.1 CD cord-006870-f5w6fw6q 486 16 % % NN cord-006870-f5w6fw6q 486 17 . . . cord-006870-f5w6fw6q 487 1 The the DT cord-006870-f5w6fw6q 487 2 ICER ICER NNP cord-006870-f5w6fw6q 487 3 was be VBD cord-006870-f5w6fw6q 487 4 $ $ $ cord-006870-f5w6fw6q 487 5 57 57 CD cord-006870-f5w6fw6q 487 6 for for IN cord-006870-f5w6fw6q 487 7 each each DT cord-006870-f5w6fw6q 487 8 1 1 CD cord-006870-f5w6fw6q 487 9 % % NN cord-006870-f5w6fw6q 487 10 increase increase NN cord-006870-f5w6fw6q 487 11 in in IN cord-006870-f5w6fw6q 487 12 SSPR SSPR NNP cord-006870-f5w6fw6q 487 13 with with IN cord-006870-f5w6fw6q 487 14 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 487 15 . . . cord-006870-f5w6fw6q 488 1 The the DT cord-006870-f5w6fw6q 488 2 SSPR SSPR NNS cord-006870-f5w6fw6q 488 3 of of IN cord-006870-f5w6fw6q 488 4 phenytoin phenytoin NN cord-006870-f5w6fw6q 488 5 and and CC cord-006870-f5w6fw6q 488 6 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 488 7 were be VBD cord-006870-f5w6fw6q 488 8 similar similar JJ cord-006870-f5w6fw6q 488 9 . . . cord-006870-f5w6fw6q 489 1 Because because IN cord-006870-f5w6fw6q 489 2 patients patient NNS cord-006870-f5w6fw6q 489 3 who who WP cord-006870-f5w6fw6q 489 4 received receive VBD cord-006870-f5w6fw6q 489 5 phenytoin phenytoin NN cord-006870-f5w6fw6q 489 6 may may MD cord-006870-f5w6fw6q 489 7 differ differ VB cord-006870-f5w6fw6q 489 8 from from IN cord-006870-f5w6fw6q 489 9 those those DT cord-006870-f5w6fw6q 489 10 who who WP cord-006870-f5w6fw6q 489 11 received receive VBD cord-006870-f5w6fw6q 489 12 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 489 13 , , , cord-006870-f5w6fw6q 489 14 further further JJ cord-006870-f5w6fw6q 489 15 analysis analysis NN cord-006870-f5w6fw6q 489 16 is be VBZ cord-006870-f5w6fw6q 489 17 needed need VBN cord-006870-f5w6fw6q 489 18 prior prior RB cord-006870-f5w6fw6q 489 19 to to IN cord-006870-f5w6fw6q 489 20 drawing draw VBG cord-006870-f5w6fw6q 489 21 any any DT cord-006870-f5w6fw6q 489 22 conclusions conclusion NNS cord-006870-f5w6fw6q 489 23 about about IN cord-006870-f5w6fw6q 489 24 the the DT cord-006870-f5w6fw6q 489 25 cost cost NN cord-006870-f5w6fw6q 489 26 - - HYPH cord-006870-f5w6fw6q 489 27 effectiveness effectiveness NN cord-006870-f5w6fw6q 489 28 of of IN cord-006870-f5w6fw6q 489 29 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 489 30 relative relative JJ cord-006870-f5w6fw6q 489 31 to to IN cord-006870-f5w6fw6q 489 32 phenytoin phenytoin NN cord-006870-f5w6fw6q 489 33 . . . cord-006870-f5w6fw6q 490 1 Augmented augment VBN cord-006870-f5w6fw6q 490 2 renal renal JJ cord-006870-f5w6fw6q 490 3 clearance clearance NN cord-006870-f5w6fw6q 490 4 ( ( -LRB- cord-006870-f5w6fw6q 490 5 ARC ARC NNP cord-006870-f5w6fw6q 490 6 ) ) -RRB- cord-006870-f5w6fw6q 490 7 has have VBZ cord-006870-f5w6fw6q 490 8 been be VBN cord-006870-f5w6fw6q 490 9 reported report VBN cord-006870-f5w6fw6q 490 10 in in IN cord-006870-f5w6fw6q 490 11 up up RB cord-006870-f5w6fw6q 490 12 85 85 CD cord-006870-f5w6fw6q 490 13 % % NN cord-006870-f5w6fw6q 490 14 of of IN cord-006870-f5w6fw6q 490 15 critically critically RB cord-006870-f5w6fw6q 490 16 ill ill JJ cord-006870-f5w6fw6q 490 17 TBI TBI NNP cord-006870-f5w6fw6q 490 18 patients patient NNS cord-006870-f5w6fw6q 490 19 and and CC cord-006870-f5w6fw6q 490 20 may may MD cord-006870-f5w6fw6q 490 21 impact impact VB cord-006870-f5w6fw6q 490 22 therapeutic therapeutic JJ cord-006870-f5w6fw6q 490 23 drug drug NN cord-006870-f5w6fw6q 490 24 concentrations concentration NNS cord-006870-f5w6fw6q 490 25 . . . cord-006870-f5w6fw6q 491 1 Improved improved JJ cord-006870-f5w6fw6q 491 2 predictors predictor NNS cord-006870-f5w6fw6q 491 3 of of IN cord-006870-f5w6fw6q 491 4 ARC ARC NNP cord-006870-f5w6fw6q 491 5 are be VBP cord-006870-f5w6fw6q 491 6 needed need VBN cord-006870-f5w6fw6q 491 7 . . . cord-006870-f5w6fw6q 492 1 Serum serum NN cord-006870-f5w6fw6q 492 2 CysC CysC NNP cord-006870-f5w6fw6q 492 3 , , , cord-006870-f5w6fw6q 492 4 a a DT cord-006870-f5w6fw6q 492 5 validated validate VBN cord-006870-f5w6fw6q 492 6 marker marker NN cord-006870-f5w6fw6q 492 7 of of IN cord-006870-f5w6fw6q 492 8 glomerular glomerular JJ cord-006870-f5w6fw6q 492 9 filtration filtration NN cord-006870-f5w6fw6q 492 10 , , , cord-006870-f5w6fw6q 492 11 has have VBZ cord-006870-f5w6fw6q 492 12 not not RB cord-006870-f5w6fw6q 492 13 been be VBN cord-006870-f5w6fw6q 492 14 examined examine VBN cord-006870-f5w6fw6q 492 15 as as IN cord-006870-f5w6fw6q 492 16 a a DT cord-006870-f5w6fw6q 492 17 marker marker NN cord-006870-f5w6fw6q 492 18 for for IN cord-006870-f5w6fw6q 492 19 ARC ARC NNP cord-006870-f5w6fw6q 492 20 in in IN cord-006870-f5w6fw6q 492 21 critically critically RB cord-006870-f5w6fw6q 492 22 ill ill JJ cord-006870-f5w6fw6q 492 23 TBI TBI NNP cord-006870-f5w6fw6q 492 24 patients patient NNS cord-006870-f5w6fw6q 492 25 . . . cord-006870-f5w6fw6q 493 1 This this DT cord-006870-f5w6fw6q 493 2 pilot pilot NN cord-006870-f5w6fw6q 493 3 study study NN cord-006870-f5w6fw6q 493 4 tested test VBD cord-006870-f5w6fw6q 493 5 the the DT cord-006870-f5w6fw6q 493 6 hypothesis hypothesis NN cord-006870-f5w6fw6q 493 7 that that IN cord-006870-f5w6fw6q 493 8 serum serum NN cord-006870-f5w6fw6q 493 9 CysC CysC NNP cord-006870-f5w6fw6q 493 10 concentrations concentration NNS cord-006870-f5w6fw6q 493 11 are be VBP cord-006870-f5w6fw6q 493 12 lower low JJR cord-006870-f5w6fw6q 493 13 than than IN cord-006870-f5w6fw6q 493 14 reference reference NN cord-006870-f5w6fw6q 493 15 values value NNS cord-006870-f5w6fw6q 493 16 following follow VBG cord-006870-f5w6fw6q 493 17 TBI TBI NNP cord-006870-f5w6fw6q 493 18 . . . cord-006870-f5w6fw6q 494 1 Adult adult JJ cord-006870-f5w6fw6q 494 2 TBI TBI NNP cord-006870-f5w6fw6q 494 3 patients patient NNS cord-006870-f5w6fw6q 494 4 enrolled enrol VBN cord-006870-f5w6fw6q 494 5 in in IN cord-006870-f5w6fw6q 494 6 the the DT cord-006870-f5w6fw6q 494 7 UKCCTS UKCCTS NNP cord-006870-f5w6fw6q 494 8 - - HYPH cord-006870-f5w6fw6q 494 9 UNCTracs UNCTracs NNP cord-006870-f5w6fw6q 494 10 prospective prospective JJ cord-006870-f5w6fw6q 494 11 study study NN cord-006870-f5w6fw6q 494 12 of of IN cord-006870-f5w6fw6q 494 13 ARC ARC NNP cord-006870-f5w6fw6q 494 14 effects effect NNS cord-006870-f5w6fw6q 494 15 on on IN cord-006870-f5w6fw6q 494 16 drug drug NN cord-006870-f5w6fw6q 494 17 clearance clearance NN cord-006870-f5w6fw6q 494 18 , , , cord-006870-f5w6fw6q 494 19 were be VBD cord-006870-f5w6fw6q 494 20 eligible eligible JJ cord-006870-f5w6fw6q 494 21 . . . cord-006870-f5w6fw6q 495 1 CysC CysC NNP cord-006870-f5w6fw6q 495 2 serum serum NN cord-006870-f5w6fw6q 495 3 concentrations concentration NNS cord-006870-f5w6fw6q 495 4 ( ( -LRB- cord-006870-f5w6fw6q 495 5 ELISA ELISA NNP cord-006870-f5w6fw6q 495 6 -R -R : cord-006870-f5w6fw6q 495 7 & & CC cord-006870-f5w6fw6q 495 8 D D NNP cord-006870-f5w6fw6q 495 9 CysC CysC NNP cord-006870-f5w6fw6q 495 10 ) ) -RRB- cord-006870-f5w6fw6q 495 11 were be VBD cord-006870-f5w6fw6q 495 12 measured measure VBN cord-006870-f5w6fw6q 495 13 daily daily RB cord-006870-f5w6fw6q 495 14 for for IN cord-006870-f5w6fw6q 495 15 up up IN cord-006870-f5w6fw6q 495 16 to to TO cord-006870-f5w6fw6q 495 17 7 7 CD cord-006870-f5w6fw6q 495 18 days day NNS cord-006870-f5w6fw6q 495 19 and and CC cord-006870-f5w6fw6q 495 20 compared compare VBN cord-006870-f5w6fw6q 495 21 to to IN cord-006870-f5w6fw6q 495 22 reference reference NN cord-006870-f5w6fw6q 495 23 values value NNS cord-006870-f5w6fw6q 495 24 . . . cord-006870-f5w6fw6q 496 1 Descriptive descriptive JJ cord-006870-f5w6fw6q 496 2 statistics statistic NNS cord-006870-f5w6fw6q 496 3 and and CC cord-006870-f5w6fw6q 496 4 student student NN cord-006870-f5w6fw6q 496 5 t t NN cord-006870-f5w6fw6q 496 6 - - HYPH cord-006870-f5w6fw6q 496 7 test test NN cord-006870-f5w6fw6q 496 8 for for IN cord-006870-f5w6fw6q 496 9 continuous continuous JJ cord-006870-f5w6fw6q 496 10 measures measure NNS cord-006870-f5w6fw6q 497 1 ( ( -LRB- cord-006870-f5w6fw6q 497 2 Patient Patient NNP cord-006870-f5w6fw6q 497 3 vs. vs. IN cord-006870-f5w6fw6q 497 4 reference reference NN cord-006870-f5w6fw6q 497 5 lower low JJR cord-006870-f5w6fw6q 497 6 range range NN cord-006870-f5w6fw6q 497 7 CysC CysC NNP cord-006870-f5w6fw6q 497 8 ) ) -RRB- cord-006870-f5w6fw6q 497 9 were be VBD cord-006870-f5w6fw6q 497 10 calculated calculate VBN cord-006870-f5w6fw6q 497 11 . . . cord-006870-f5w6fw6q 498 1 The the DT cord-006870-f5w6fw6q 498 2 first first JJ cord-006870-f5w6fw6q 498 3 ten ten CD cord-006870-f5w6fw6q 498 4 patients patient NNS cord-006870-f5w6fw6q 498 5 [ [ -LRB- cord-006870-f5w6fw6q 498 6 7M/3F 7m/3f CD cord-006870-f5w6fw6q 498 7 , , , cord-006870-f5w6fw6q 498 8 mean mean VB cord-006870-f5w6fw6q 498 9 age= age= NNP cord-006870-f5w6fw6q 498 10 41.5years 41.5years CD cord-006870-f5w6fw6q 498 11 ( ( -LRB- cord-006870-f5w6fw6q 498 12 18 18 CD cord-006870-f5w6fw6q 498 13 - - SYM cord-006870-f5w6fw6q 498 14 59 59 CD cord-006870-f5w6fw6q 498 15 y y NN cord-006870-f5w6fw6q 498 16 / / SYM cord-006870-f5w6fw6q 498 17 o o NN cord-006870-f5w6fw6q 498 18 ) ) -RRB- cord-006870-f5w6fw6q 498 19 , , , cord-006870-f5w6fw6q 498 20 median median JJ cord-006870-f5w6fw6q 498 21 GCS=6 GCS=6 NNP cord-006870-f5w6fw6q 498 22 ( ( -LRB- cord-006870-f5w6fw6q 498 23 IQR3 IQR3 NNP cord-006870-f5w6fw6q 498 24 - - HYPH cord-006870-f5w6fw6q 498 25 7 7 CD cord-006870-f5w6fw6q 498 26 ) ) -RRB- cord-006870-f5w6fw6q 498 27 ] ] -RRB- cord-006870-f5w6fw6q 498 28 provided provide VBD cord-006870-f5w6fw6q 498 29 a a DT cord-006870-f5w6fw6q 498 30 total total NN cord-006870-f5w6fw6q 498 31 of of IN cord-006870-f5w6fw6q 498 32 49 49 CD cord-006870-f5w6fw6q 498 33 serum serum NN cord-006870-f5w6fw6q 498 34 CysC CysC NNP cord-006870-f5w6fw6q 498 35 for for IN cord-006870-f5w6fw6q 498 36 analysis analysis NN cord-006870-f5w6fw6q 498 37 . . . cord-006870-f5w6fw6q 499 1 Each each DT cord-006870-f5w6fw6q 499 2 patient patient NN cord-006870-f5w6fw6q 499 3 provided provide VBN cord-006870-f5w6fw6q 499 4 at at IN cord-006870-f5w6fw6q 499 5 least least JJS cord-006870-f5w6fw6q 499 6 4 4 CD cord-006870-f5w6fw6q 499 7 samples sample NNS cord-006870-f5w6fw6q 499 8 ( ( -LRB- cord-006870-f5w6fw6q 499 9 range range NNP cord-006870-f5w6fw6q 499 10 4 4 CD cord-006870-f5w6fw6q 499 11 - - SYM cord-006870-f5w6fw6q 499 12 7 7 CD cord-006870-f5w6fw6q 499 13 ) ) -RRB- cord-006870-f5w6fw6q 499 14 for for IN cord-006870-f5w6fw6q 499 15 up up IN cord-006870-f5w6fw6q 499 16 to to TO cord-006870-f5w6fw6q 499 17 seven seven CD cord-006870-f5w6fw6q 499 18 days day NNS cord-006870-f5w6fw6q 499 19 . . . cord-006870-f5w6fw6q 500 1 Measured measured JJ cord-006870-f5w6fw6q 500 2 serum serum NN cord-006870-f5w6fw6q 500 3 CysC CysC NNP cord-006870-f5w6fw6q 500 4 concentrations concentration NNS cord-006870-f5w6fw6q 500 5 were be VBD cord-006870-f5w6fw6q 500 6 below below IN cord-006870-f5w6fw6q 500 7 the the DT cord-006870-f5w6fw6q 500 8 reference reference NN cord-006870-f5w6fw6q 500 9 range range NN cord-006870-f5w6fw6q 500 10 in in IN cord-006870-f5w6fw6q 500 11 24 24 CD cord-006870-f5w6fw6q 500 12 of of IN cord-006870-f5w6fw6q 500 13 49 49 CD cord-006870-f5w6fw6q 500 14 samples sample NNS cord-006870-f5w6fw6q 500 15 . . . cord-006870-f5w6fw6q 501 1 The the DT cord-006870-f5w6fw6q 501 2 overall overall JJ cord-006870-f5w6fw6q 501 3 mean mean JJ cord-006870-f5w6fw6q 501 4 CysC CysC NNP cord-006870-f5w6fw6q 501 5 concentration concentration NN cord-006870-f5w6fw6q 501 6 was be VBD cord-006870-f5w6fw6q 501 7 0.589 0.589 CD cord-006870-f5w6fw6q 501 8 + + SYM cord-006870-f5w6fw6q 501 9 0.132 0.132 CD cord-006870-f5w6fw6q 501 10 mg mg NNP cord-006870-f5w6fw6q 501 11 / / SYM cord-006870-f5w6fw6q 501 12 L l NN cord-006870-f5w6fw6q 502 1 vs vs IN cord-006870-f5w6fw6q 502 2 expected expect VBN cord-006870-f5w6fw6q 502 3 mean mean NN cord-006870-f5w6fw6q 502 4 of of IN cord-006870-f5w6fw6q 502 5 0.621 0.621 CD cord-006870-f5w6fw6q 502 6 + + SYM cord-006870-f5w6fw6q 502 7 0.05 0.05 CD cord-006870-f5w6fw6q 502 8 . . . cord-006870-f5w6fw6q 503 1 ( ( -LRB- cord-006870-f5w6fw6q 503 2 NS NS NNP cord-006870-f5w6fw6q 503 3 ) ) -RRB- cord-006870-f5w6fw6q 504 1 Measured measure VBN cord-006870-f5w6fw6q 504 2 values value NNS cord-006870-f5w6fw6q 504 3 fell fall VBD cord-006870-f5w6fw6q 504 4 below below IN cord-006870-f5w6fw6q 504 5 the the DT cord-006870-f5w6fw6q 504 6 lower low JJR cord-006870-f5w6fw6q 504 7 reference reference NN cord-006870-f5w6fw6q 504 8 range range NN cord-006870-f5w6fw6q 504 9 in in IN cord-006870-f5w6fw6q 504 10 5 5 CD cord-006870-f5w6fw6q 504 11 patients patient NNS cord-006870-f5w6fw6q 504 12 ( ( -LRB- cord-006870-f5w6fw6q 504 13 2M/3F 2m/3f CD cord-006870-f5w6fw6q 504 14 ) ) -RRB- cord-006870-f5w6fw6q 504 15 for for IN cord-006870-f5w6fw6q 504 16 the the DT cord-006870-f5w6fw6q 504 17 first first JJ cord-006870-f5w6fw6q 504 18 4 4 CD cord-006870-f5w6fw6q 504 19 study study NN cord-006870-f5w6fw6q 504 20 days day NNS cord-006870-f5w6fw6q 505 1 ( ( -LRB- cord-006870-f5w6fw6q 505 2 Mean mean JJ cord-006870-f5w6fw6q 505 3 = = NFP cord-006870-f5w6fw6q 505 4 0.483 0.483 CD cord-006870-f5w6fw6q 506 1 + + CC cord-006870-f5w6fw6q 507 1 0.101 0.101 CD cord-006870-f5w6fw6q 508 1 vs vs IN cord-006870-f5w6fw6q 508 2 0.622 0.622 CD cord-006870-f5w6fw6q 508 3 + + SYM cord-006870-f5w6fw6q 508 4 0.067 0.067 CD cord-006870-f5w6fw6q 508 5 p<0.05 p<0.05 CD cord-006870-f5w6fw6q 508 6 ) ) -RRB- cord-006870-f5w6fw6q 508 7 . . . cord-006870-f5w6fw6q 509 1 The the DT cord-006870-f5w6fw6q 509 2 mean mean JJ cord-006870-f5w6fw6q 509 3 difference difference NN cord-006870-f5w6fw6q 509 4 between between IN cord-006870-f5w6fw6q 509 5 measured measured JJ cord-006870-f5w6fw6q 509 6 concentration concentration NN cord-006870-f5w6fw6q 509 7 and and CC cord-006870-f5w6fw6q 509 8 reference reference NN cord-006870-f5w6fw6q 509 9 value value NN cord-006870-f5w6fw6q 509 10 was be VBD cord-006870-f5w6fw6q 509 11 0.139 0.139 CD cord-006870-f5w6fw6q 509 12 + + CC cord-006870-f5w6fw6q 510 1 0.07 0.07 CD cord-006870-f5w6fw6q 510 2 mg mg NNP cord-006870-f5w6fw6q 510 3 / / SYM cord-006870-f5w6fw6q 510 4 L. L. NNP cord-006870-f5w6fw6q 511 1 After after IN cord-006870-f5w6fw6q 511 2 4 4 CD cord-006870-f5w6fw6q 511 3 days day NNS cord-006870-f5w6fw6q 511 4 , , , cord-006870-f5w6fw6q 511 5 four four CD cord-006870-f5w6fw6q 511 6 patients patient NNS cord-006870-f5w6fw6q 511 7 ( ( -LRB- cord-006870-f5w6fw6q 511 8 2M/2F 2m/2f CD cord-006870-f5w6fw6q 511 9 ) ) -RRB- cord-006870-f5w6fw6q 511 10 remained remain VBD cord-006870-f5w6fw6q 511 11 below below IN cord-006870-f5w6fw6q 511 12 reference reference NN cord-006870-f5w6fw6q 511 13 values value NNS cord-006870-f5w6fw6q 511 14 with with IN cord-006870-f5w6fw6q 511 15 a a DT cord-006870-f5w6fw6q 511 16 mean mean JJ cord-006870-f5w6fw6q 511 17 difference difference NN cord-006870-f5w6fw6q 511 18 of of IN cord-006870-f5w6fw6q 511 19 0.14 0.14 CD cord-006870-f5w6fw6q 511 20 + + SYM cord-006870-f5w6fw6q 511 21 0.06 0.06 CD cord-006870-f5w6fw6q 511 22 mg mg NNP cord-006870-f5w6fw6q 511 23 / / SYM cord-006870-f5w6fw6q 511 24 dl dl NNP cord-006870-f5w6fw6q 511 25 . . . cord-006870-f5w6fw6q 512 1 Preliminary preliminary JJ cord-006870-f5w6fw6q 512 2 results result NNS cord-006870-f5w6fw6q 512 3 show show VBP cord-006870-f5w6fw6q 512 4 CysC CysC NNP cord-006870-f5w6fw6q 512 5 was be VBD cord-006870-f5w6fw6q 512 6 not not RB cord-006870-f5w6fw6q 512 7 consistently consistently RB cord-006870-f5w6fw6q 512 8 below below IN cord-006870-f5w6fw6q 512 9 reference reference NN cord-006870-f5w6fw6q 512 10 ranges range NNS cord-006870-f5w6fw6q 512 11 in in IN cord-006870-f5w6fw6q 512 12 all all DT cord-006870-f5w6fw6q 512 13 TBI TBI NNP cord-006870-f5w6fw6q 512 14 subjects subject NNS cord-006870-f5w6fw6q 512 15 . . . cord-006870-f5w6fw6q 513 1 A a DT cord-006870-f5w6fw6q 513 2 subset subset NN cord-006870-f5w6fw6q 513 3 of of IN cord-006870-f5w6fw6q 513 4 subjects subject NNS cord-006870-f5w6fw6q 513 5 showed show VBD cord-006870-f5w6fw6q 513 6 significantly significantly RB cord-006870-f5w6fw6q 513 7 lower low JJR cord-006870-f5w6fw6q 513 8 CysC CysC NNP cord-006870-f5w6fw6q 513 9 within within IN cord-006870-f5w6fw6q 513 10 seven seven CD cord-006870-f5w6fw6q 513 11 days day NNS cord-006870-f5w6fw6q 513 12 of of IN cord-006870-f5w6fw6q 513 13 injury injury NN cord-006870-f5w6fw6q 513 14 . . . cord-006870-f5w6fw6q 514 1 The the DT cord-006870-f5w6fw6q 514 2 relationship relationship NN cord-006870-f5w6fw6q 514 3 between between IN cord-006870-f5w6fw6q 514 4 CysC CysC NNP cord-006870-f5w6fw6q 514 5 and and CC cord-006870-f5w6fw6q 514 6 ARC ARC NNP cord-006870-f5w6fw6q 514 7 needs need VBZ cord-006870-f5w6fw6q 514 8 to to TO cord-006870-f5w6fw6q 514 9 be be VB cord-006870-f5w6fw6q 514 10 further further RB cord-006870-f5w6fw6q 514 11 examined examine VBN cord-006870-f5w6fw6q 514 12 as as IN cord-006870-f5w6fw6q 514 13 analysis analysis NN cord-006870-f5w6fw6q 514 14 continues continue VBZ cord-006870-f5w6fw6q 514 15 . . . cord-006870-f5w6fw6q 515 1 Functional functional JJ cord-006870-f5w6fw6q 515 2 connectivity connectivity NN cord-006870-f5w6fw6q 515 3 of of IN cord-006870-f5w6fw6q 515 4 the the DT cord-006870-f5w6fw6q 515 5 default default NN cord-006870-f5w6fw6q 515 6 mode mode NN cord-006870-f5w6fw6q 515 7 network network NN cord-006870-f5w6fw6q 515 8 ( ( -LRB- cord-006870-f5w6fw6q 515 9 DMN DMN NNP cord-006870-f5w6fw6q 515 10 ) ) -RRB- cord-006870-f5w6fw6q 515 11 is be VBZ cord-006870-f5w6fw6q 515 12 believed believe VBN cord-006870-f5w6fw6q 515 13 to to TO cord-006870-f5w6fw6q 515 14 be be VB cord-006870-f5w6fw6q 515 15 necessary necessary JJ cord-006870-f5w6fw6q 515 16 for for IN cord-006870-f5w6fw6q 515 17 recovery recovery NN cord-006870-f5w6fw6q 515 18 of of IN cord-006870-f5w6fw6q 515 19 consciousness consciousness NN cord-006870-f5w6fw6q 515 20 after after IN cord-006870-f5w6fw6q 515 21 coma coma NN cord-006870-f5w6fw6q 515 22 . . . cord-006870-f5w6fw6q 516 1 However however RB cord-006870-f5w6fw6q 516 2 , , , cord-006870-f5w6fw6q 516 3 DMN DMN NNP cord-006870-f5w6fw6q 516 4 connectivity connectivity NN cord-006870-f5w6fw6q 516 5 has have VBZ cord-006870-f5w6fw6q 516 6 not not RB cord-006870-f5w6fw6q 516 7 been be VBN cord-006870-f5w6fw6q 516 8 comprehensively comprehensively RB cord-006870-f5w6fw6q 516 9 studied study VBN cord-006870-f5w6fw6q 516 10 in in IN cord-006870-f5w6fw6q 516 11 patients patient NNS cord-006870-f5w6fw6q 516 12 with with IN cord-006870-f5w6fw6q 516 13 acute acute JJ cord-006870-f5w6fw6q 516 14 severe severe JJ cord-006870-f5w6fw6q 516 15 TBI tbi NN cord-006870-f5w6fw6q 516 16 . . . cord-006870-f5w6fw6q 517 1 We -PRON- PRP cord-006870-f5w6fw6q 517 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 517 3 that that IN cord-006870-f5w6fw6q 517 4 DMN DMN NNP cord-006870-f5w6fw6q 517 5 connectivity connectivity NN cord-006870-f5w6fw6q 517 6 in in IN cord-006870-f5w6fw6q 517 7 patients patient NNS cord-006870-f5w6fw6q 517 8 with with IN cord-006870-f5w6fw6q 517 9 acute acute JJ cord-006870-f5w6fw6q 517 10 severe severe JJ cord-006870-f5w6fw6q 517 11 TBI TBI NNP cord-006870-f5w6fw6q 517 12 is be VBZ cord-006870-f5w6fw6q 517 13 associated associate VBN cord-006870-f5w6fw6q 517 14 with with IN cord-006870-f5w6fw6q 517 15 level level NN cord-006870-f5w6fw6q 517 16 of of IN cord-006870-f5w6fw6q 517 17 consciousness consciousness NN cord-006870-f5w6fw6q 517 18 . . . cord-006870-f5w6fw6q 518 1 We -PRON- PRP cord-006870-f5w6fw6q 518 2 prospectively prospectively RB cord-006870-f5w6fw6q 518 3 enrolled enrol VBD cord-006870-f5w6fw6q 518 4 patients patient NNS cord-006870-f5w6fw6q 518 5 admitted admit VBN cord-006870-f5w6fw6q 518 6 to to IN cord-006870-f5w6fw6q 518 7 the the DT cord-006870-f5w6fw6q 518 8 intensive intensive JJ cord-006870-f5w6fw6q 518 9 care care NN cord-006870-f5w6fw6q 518 10 unit unit NN cord-006870-f5w6fw6q 518 11 for for IN cord-006870-f5w6fw6q 518 12 acute acute JJ cord-006870-f5w6fw6q 518 13 severe severe JJ cord-006870-f5w6fw6q 518 14 TBI tbi NN cord-006870-f5w6fw6q 518 15 and and CC cord-006870-f5w6fw6q 518 16 performed perform VBN cord-006870-f5w6fw6q 518 17 resting rest VBG cord-006870-f5w6fw6q 518 18 - - HYPH cord-006870-f5w6fw6q 518 19 state state NN cord-006870-f5w6fw6q 518 20 functional functional JJ cord-006870-f5w6fw6q 518 21 MRI MRI NNP cord-006870-f5w6fw6q 518 22 ( ( -LRB- cord-006870-f5w6fw6q 518 23 rs rs NNP cord-006870-f5w6fw6q 518 24 - - HYPH cord-006870-f5w6fw6q 518 25 fMRI fMRI NNP cord-006870-f5w6fw6q 518 26 ) ) -RRB- cord-006870-f5w6fw6q 518 27 as as RB cord-006870-f5w6fw6q 518 28 soon soon RB cord-006870-f5w6fw6q 518 29 as as RB cord-006870-f5w6fw6q 518 30 safely safely RB cord-006870-f5w6fw6q 518 31 possible possible JJ cord-006870-f5w6fw6q 518 32 . . . cord-006870-f5w6fw6q 519 1 DMN DMN NNP cord-006870-f5w6fw6q 519 2 functional functional JJ cord-006870-f5w6fw6q 519 3 connectivity connectivity NN cord-006870-f5w6fw6q 519 4 was be VBD cord-006870-f5w6fw6q 519 5 assessed assess VBN cord-006870-f5w6fw6q 519 6 by by IN cord-006870-f5w6fw6q 519 7 rs rs NNP cord-006870-f5w6fw6q 519 8 - - HYPH cord-006870-f5w6fw6q 519 9 fMRI fmri NN cord-006870-f5w6fw6q 519 10 analysis analysis NN cord-006870-f5w6fw6q 519 11 of of IN cord-006870-f5w6fw6q 519 12 the the DT cord-006870-f5w6fw6q 519 13 blood blood NN cord-006870-f5w6fw6q 519 14 - - HYPH cord-006870-f5w6fw6q 519 15 oxygen oxygen NN cord-006870-f5w6fw6q 519 16 level level NN cord-006870-f5w6fw6q 519 17 dependent dependent JJ cord-006870-f5w6fw6q 519 18 ( ( -LRB- cord-006870-f5w6fw6q 519 19 BOLD bold JJ cord-006870-f5w6fw6q 519 20 ) ) -RRB- cord-006870-f5w6fw6q 519 21 signal signal NN cord-006870-f5w6fw6q 519 22 using use VBG cord-006870-f5w6fw6q 519 23 a a DT cord-006870-f5w6fw6q 519 24 seed seed NN cord-006870-f5w6fw6q 519 25 - - HYPH cord-006870-f5w6fw6q 519 26 based base VBN cord-006870-f5w6fw6q 519 27 approach approach NN cord-006870-f5w6fw6q 519 28 . . . cord-006870-f5w6fw6q 520 1 Pearson Pearson NNP cord-006870-f5w6fw6q 520 2 's 's POS cord-006870-f5w6fw6q 520 3 correlation correlation NN cord-006870-f5w6fw6q 520 4 coefficients coefficient NNS cord-006870-f5w6fw6q 520 5 were be VBD cord-006870-f5w6fw6q 520 6 calculated calculate VBN cord-006870-f5w6fw6q 520 7 between between IN cord-006870-f5w6fw6q 520 8 the the DT cord-006870-f5w6fw6q 520 9 mean mean JJ cord-006870-f5w6fw6q 520 10 BOLD bold JJ cord-006870-f5w6fw6q 520 11 time time NN cord-006870-f5w6fw6q 520 12 series series NN cord-006870-f5w6fw6q 520 13 within within IN cord-006870-f5w6fw6q 520 14 DMN DMN NNP cord-006870-f5w6fw6q 520 15 nodes node NNS cord-006870-f5w6fw6q 520 16 and and CC cord-006870-f5w6fw6q 520 17 all all DT cord-006870-f5w6fw6q 520 18 other other JJ cord-006870-f5w6fw6q 520 19 regions region NNS cord-006870-f5w6fw6q 520 20 in in IN cord-006870-f5w6fw6q 520 21 the the DT cord-006870-f5w6fw6q 520 22 brain brain NN cord-006870-f5w6fw6q 520 23 . . . cord-006870-f5w6fw6q 521 1 Level level NN cord-006870-f5w6fw6q 521 2 of of IN cord-006870-f5w6fw6q 521 3 consciousness consciousness NN cord-006870-f5w6fw6q 521 4 was be VBD cord-006870-f5w6fw6q 521 5 assessed assess VBN cord-006870-f5w6fw6q 521 6 at at IN cord-006870-f5w6fw6q 521 7 the the DT cord-006870-f5w6fw6q 521 8 time time NN cord-006870-f5w6fw6q 521 9 of of IN cord-006870-f5w6fw6q 521 10 the the DT cord-006870-f5w6fw6q 521 11 scan scan NN cord-006870-f5w6fw6q 521 12 using use VBG cord-006870-f5w6fw6q 521 13 the the DT cord-006870-f5w6fw6q 521 14 Coma Coma NNP cord-006870-f5w6fw6q 521 15 Recovery Recovery NNP cord-006870-f5w6fw6q 521 16 Scale scale NN cord-006870-f5w6fw6q 521 17 - - HYPH cord-006870-f5w6fw6q 521 18 Revised revise VBN cord-006870-f5w6fw6q 521 19 ( ( -LRB- cord-006870-f5w6fw6q 521 20 CRS CRS NNP cord-006870-f5w6fw6q 521 21 - - HYPH cord-006870-f5w6fw6q 521 22 R R NNP cord-006870-f5w6fw6q 521 23 ) ) -RRB- cord-006870-f5w6fw6q 521 24 . . . cord-006870-f5w6fw6q 522 1 Two two CD cord-006870-f5w6fw6q 522 2 - - HYPH cord-006870-f5w6fw6q 522 3 sample sample NN cord-006870-f5w6fw6q 522 4 t t NN cord-006870-f5w6fw6q 522 5 - - HYPH cord-006870-f5w6fw6q 522 6 tests test NNS cord-006870-f5w6fw6q 522 7 were be VBD cord-006870-f5w6fw6q 522 8 performed perform VBN cord-006870-f5w6fw6q 522 9 to to TO cord-006870-f5w6fw6q 522 10 identify identify VB cord-006870-f5w6fw6q 522 11 brain brain NN cord-006870-f5w6fw6q 522 12 regions region NNS cord-006870-f5w6fw6q 522 13 with with IN cord-006870-f5w6fw6q 522 14 connectivity connectivity NN cord-006870-f5w6fw6q 522 15 differences difference NNS cord-006870-f5w6fw6q 522 16 between between IN cord-006870-f5w6fw6q 522 17 conscious conscious JJ cord-006870-f5w6fw6q 522 18 and and CC cord-006870-f5w6fw6q 522 19 unconscious unconscious JJ cord-006870-f5w6fw6q 522 20 subjects subject NNS cord-006870-f5w6fw6q 522 21 . . . cord-006870-f5w6fw6q 523 1 We -PRON- PRP cord-006870-f5w6fw6q 523 2 then then RB cord-006870-f5w6fw6q 523 3 tested test VBD cord-006870-f5w6fw6q 523 4 for for IN cord-006870-f5w6fw6q 523 5 associations association NNS cord-006870-f5w6fw6q 523 6 between between IN cord-006870-f5w6fw6q 523 7 level level NN cord-006870-f5w6fw6q 523 8 of of IN cord-006870-f5w6fw6q 523 9 consciousness consciousness NN cord-006870-f5w6fw6q 523 10 and and CC cord-006870-f5w6fw6q 523 11 DMN DMN NNP cord-006870-f5w6fw6q 523 12 connectivity connectivity NN cord-006870-f5w6fw6q 523 13 within within IN cord-006870-f5w6fw6q 523 14 these these DT cord-006870-f5w6fw6q 523 15 regions region NNS cord-006870-f5w6fw6q 523 16 . . . cord-006870-f5w6fw6q 524 1 We -PRON- PRP cord-006870-f5w6fw6q 524 2 enrolled enrol VBD cord-006870-f5w6fw6q 524 3 16 16 CD cord-006870-f5w6fw6q 524 4 patients patient NNS cord-006870-f5w6fw6q 524 5 ( ( -LRB- cord-006870-f5w6fw6q 524 6 12 12 CD cord-006870-f5w6fw6q 524 7 male male NN cord-006870-f5w6fw6q 524 8 , , , cord-006870-f5w6fw6q 524 9 mean+/-SD mean+/-sd NN cord-006870-f5w6fw6q 524 10 age age NN cord-006870-f5w6fw6q 524 11 30+/-8 30+/-8 CD cord-006870-f5w6fw6q 524 12 years year NNS cord-006870-f5w6fw6q 524 13 ) ) -RRB- cord-006870-f5w6fw6q 524 14 and and CC cord-006870-f5w6fw6q 524 15 16 16 CD cord-006870-f5w6fw6q 524 16 matched match VBN cord-006870-f5w6fw6q 524 17 controls control NNS cord-006870-f5w6fw6q 524 18 ( ( -LRB- cord-006870-f5w6fw6q 524 19 11 11 CD cord-006870-f5w6fw6q 524 20 male male NN cord-006870-f5w6fw6q 524 21 , , , cord-006870-f5w6fw6q 524 22 age age NN cord-006870-f5w6fw6q 524 23 28+/-8 28+/-8 CD cord-006870-f5w6fw6q 524 24 years year NNS cord-006870-f5w6fw6q 524 25 ) ) -RRB- cord-006870-f5w6fw6q 524 26 . . . cord-006870-f5w6fw6q 525 1 RS RS NNP cord-006870-f5w6fw6q 525 2 - - HYPH cord-006870-f5w6fw6q 525 3 fMRI fMRI NNP cord-006870-f5w6fw6q 525 4 was be VBD cord-006870-f5w6fw6q 525 5 performed perform VBN cord-006870-f5w6fw6q 525 6 9.6+/-4.5 9.6+/-4.5 CD cord-006870-f5w6fw6q 525 7 days day NNS cord-006870-f5w6fw6q 525 8 post post NN cord-006870-f5w6fw6q 525 9 - - JJ cord-006870-f5w6fw6q 525 10 injury injury NN cord-006870-f5w6fw6q 525 11 . . . cord-006870-f5w6fw6q 526 1 At at IN cord-006870-f5w6fw6q 526 2 the the DT cord-006870-f5w6fw6q 526 3 time time NN cord-006870-f5w6fw6q 526 4 of of IN cord-006870-f5w6fw6q 526 5 rs rs NN cord-006870-f5w6fw6q 526 6 - - HYPH cord-006870-f5w6fw6q 526 7 fMRI fMRI NNP cord-006870-f5w6fw6q 526 8 , , , cord-006870-f5w6fw6q 526 9 patients patient NNS cord-006870-f5w6fw6q 526 10 ' ' POS cord-006870-f5w6fw6q 526 11 levels level NNS cord-006870-f5w6fw6q 526 12 of of IN cord-006870-f5w6fw6q 526 13 consciousness consciousness NN cord-006870-f5w6fw6q 526 14 were be VBD cord-006870-f5w6fw6q 526 15 coma coma NN cord-006870-f5w6fw6q 526 16 ( ( -LRB- cord-006870-f5w6fw6q 526 17 n=1 n=1 FW cord-006870-f5w6fw6q 526 18 ) ) -RRB- cord-006870-f5w6fw6q 526 19 , , , cord-006870-f5w6fw6q 526 20 vegetative vegetative JJ cord-006870-f5w6fw6q 526 21 state state NN cord-006870-f5w6fw6q 526 22 ( ( -LRB- cord-006870-f5w6fw6q 526 23 VS VS NNP cord-006870-f5w6fw6q 526 24 ; ; : cord-006870-f5w6fw6q 526 25 n=4 n=4 NNP cord-006870-f5w6fw6q 526 26 ) ) -RRB- cord-006870-f5w6fw6q 526 27 , , , cord-006870-f5w6fw6q 526 28 minimally minimally RB cord-006870-f5w6fw6q 526 29 conscious conscious JJ cord-006870-f5w6fw6q 526 30 state state NN cord-006870-f5w6fw6q 526 31 ( ( -LRB- cord-006870-f5w6fw6q 526 32 MCS MCS NNP cord-006870-f5w6fw6q 526 33 ; ; : cord-006870-f5w6fw6q 526 34 n=7 n=7 NNS cord-006870-f5w6fw6q 526 35 ) ) -RRB- cord-006870-f5w6fw6q 526 36 , , , cord-006870-f5w6fw6q 526 37 and and CC cord-006870-f5w6fw6q 526 38 post post JJ cord-006870-f5w6fw6q 526 39 - - JJ cord-006870-f5w6fw6q 526 40 traumatic traumatic JJ cord-006870-f5w6fw6q 526 41 confusional confusional JJ cord-006870-f5w6fw6q 526 42 state state NN cord-006870-f5w6fw6q 526 43 ( ( -LRB- cord-006870-f5w6fw6q 526 44 PTCS PTCS NNP cord-006870-f5w6fw6q 526 45 ; ; : cord-006870-f5w6fw6q 526 46 n=4 n=4 NNP cord-006870-f5w6fw6q 526 47 ) ) -RRB- cord-006870-f5w6fw6q 526 48 . . . cord-006870-f5w6fw6q 527 1 Connectivity connectivity NN cord-006870-f5w6fw6q 527 2 within within IN cord-006870-f5w6fw6q 527 3 the the DT cord-006870-f5w6fw6q 527 4 medial medial JJ cord-006870-f5w6fw6q 527 5 prefrontal prefrontal JJ cord-006870-f5w6fw6q 527 6 cortex cortex NNS cord-006870-f5w6fw6q 527 7 and and CC cord-006870-f5w6fw6q 527 8 posterior posterior NNP cord-006870-f5w6fw6q 527 9 cingulate cingulate NNP cord-006870-f5w6fw6q 527 10 was be VBD cord-006870-f5w6fw6q 527 11 selectively selectively RB cord-006870-f5w6fw6q 527 12 reduced reduce VBN cord-006870-f5w6fw6q 527 13 in in IN cord-006870-f5w6fw6q 527 14 unconscious unconscious JJ cord-006870-f5w6fw6q 527 15 patients patient NNS cord-006870-f5w6fw6q 527 16 ( ( -LRB- cord-006870-f5w6fw6q 527 17 coma coma NN cord-006870-f5w6fw6q 527 18 and and CC cord-006870-f5w6fw6q 527 19 VS VS NNP cord-006870-f5w6fw6q 527 20 ) ) -RRB- cord-006870-f5w6fw6q 527 21 compared compare VBN cord-006870-f5w6fw6q 527 22 to to IN cord-006870-f5w6fw6q 527 23 conscious conscious JJ cord-006870-f5w6fw6q 527 24 patients patient NNS cord-006870-f5w6fw6q 527 25 ( ( -LRB- cord-006870-f5w6fw6q 527 26 MCS MCS NNP cord-006870-f5w6fw6q 527 27 and and CC cord-006870-f5w6fw6q 527 28 PTCS PTCS NNP cord-006870-f5w6fw6q 527 29 ; ; : cord-006870-f5w6fw6q 527 30 false false JJ cord-006870-f5w6fw6q 527 31 discovery discovery NN cord-006870-f5w6fw6q 527 32 rate rate NN cord-006870-f5w6fw6q 527 33 - - HYPH cord-006870-f5w6fw6q 527 34 corrected correct VBN cord-006870-f5w6fw6q 527 35 P p NN cord-006870-f5w6fw6q 527 36 < < XX cord-006870-f5w6fw6q 527 37 0.05 0.05 CD cord-006870-f5w6fw6q 527 38 ) ) -RRB- cord-006870-f5w6fw6q 527 39 . . . cord-006870-f5w6fw6q 528 1 When when WRB cord-006870-f5w6fw6q 528 2 these these DT cord-006870-f5w6fw6q 528 3 regions region NNS cord-006870-f5w6fw6q 528 4 were be VBD cord-006870-f5w6fw6q 528 5 further further RB cord-006870-f5w6fw6q 528 6 interrogated interrogate VBN cord-006870-f5w6fw6q 528 7 , , , cord-006870-f5w6fw6q 528 8 connectivity connectivity NN cord-006870-f5w6fw6q 528 9 correlated correlate VBN cord-006870-f5w6fw6q 528 10 with with IN cord-006870-f5w6fw6q 528 11 CRS CRS NNP cord-006870-f5w6fw6q 528 12 - - HYPH cord-006870-f5w6fw6q 528 13 Conclusions Conclusions NNP cord-006870-f5w6fw6q 528 14 DMN DMN NNP cord-006870-f5w6fw6q 528 15 functional functional JJ cord-006870-f5w6fw6q 528 16 connectivity connectivity NN cord-006870-f5w6fw6q 528 17 correlates correlate VBZ cord-006870-f5w6fw6q 528 18 with with IN cord-006870-f5w6fw6q 528 19 level level NN cord-006870-f5w6fw6q 528 20 of of IN cord-006870-f5w6fw6q 528 21 consciousness consciousness NN cord-006870-f5w6fw6q 528 22 after after IN cord-006870-f5w6fw6q 528 23 acute acute JJ cord-006870-f5w6fw6q 528 24 severe severe JJ cord-006870-f5w6fw6q 528 25 TBI tbi NN cord-006870-f5w6fw6q 528 26 . . . cord-006870-f5w6fw6q 529 1 Traumatic traumatic JJ cord-006870-f5w6fw6q 529 2 brain brain NN cord-006870-f5w6fw6q 529 3 injury injury NN cord-006870-f5w6fw6q 529 4 ( ( -LRB- cord-006870-f5w6fw6q 529 5 TBI TBI NNP cord-006870-f5w6fw6q 529 6 ) ) -RRB- cord-006870-f5w6fw6q 529 7 is be VBZ cord-006870-f5w6fw6q 529 8 a a DT cord-006870-f5w6fw6q 529 9 substantial substantial JJ cord-006870-f5w6fw6q 529 10 source source NN cord-006870-f5w6fw6q 529 11 of of IN cord-006870-f5w6fw6q 529 12 death death NN cord-006870-f5w6fw6q 529 13 , , , cord-006870-f5w6fw6q 529 14 disability disability NN cord-006870-f5w6fw6q 529 15 , , , cord-006870-f5w6fw6q 529 16 and and CC cord-006870-f5w6fw6q 529 17 healthcare healthcare NN cord-006870-f5w6fw6q 529 18 utilization utilization NN cord-006870-f5w6fw6q 529 19 . . . cord-006870-f5w6fw6q 530 1 Many many JJ cord-006870-f5w6fw6q 530 2 older old JJR cord-006870-f5w6fw6q 530 3 TBI TBI NNP cord-006870-f5w6fw6q 530 4 patients patient NNS cord-006870-f5w6fw6q 530 5 present present JJ cord-006870-f5w6fw6q 530 6 to to IN cord-006870-f5w6fw6q 530 7 community community NN cord-006870-f5w6fw6q 530 8 hospitals hospital NNS cord-006870-f5w6fw6q 530 9 and and CC cord-006870-f5w6fw6q 530 10 are be VBP cord-006870-f5w6fw6q 530 11 transferred transfer VBN cord-006870-f5w6fw6q 530 12 to to IN cord-006870-f5w6fw6q 530 13 trauma trauma NN cord-006870-f5w6fw6q 530 14 centers center NNS cord-006870-f5w6fw6q 530 15 for for IN cord-006870-f5w6fw6q 530 16 further further JJ cord-006870-f5w6fw6q 530 17 care care NN cord-006870-f5w6fw6q 530 18 ; ; : cord-006870-f5w6fw6q 530 19 however however RB cord-006870-f5w6fw6q 530 20 , , , cord-006870-f5w6fw6q 530 21 little little JJ cord-006870-f5w6fw6q 530 22 is be VBZ cord-006870-f5w6fw6q 530 23 known know VBN cord-006870-f5w6fw6q 530 24 about about IN cord-006870-f5w6fw6q 530 25 the the DT cord-006870-f5w6fw6q 530 26 provision provision NN cord-006870-f5w6fw6q 530 27 of of IN cord-006870-f5w6fw6q 530 28 care care NN cord-006870-f5w6fw6q 530 29 and and CC cord-006870-f5w6fw6q 530 30 patient patient JJ cord-006870-f5w6fw6q 530 31 outcomes outcome NNS cord-006870-f5w6fw6q 530 32 at at IN cord-006870-f5w6fw6q 530 33 the the DT cord-006870-f5w6fw6q 530 34 final final JJ cord-006870-f5w6fw6q 530 35 receiving receiving NN cord-006870-f5w6fw6q 530 36 hospital hospital NN cord-006870-f5w6fw6q 530 37 . . . cord-006870-f5w6fw6q 531 1 We -PRON- PRP cord-006870-f5w6fw6q 531 2 described describe VBD cord-006870-f5w6fw6q 531 3 trauma trauma NN cord-006870-f5w6fw6q 531 4 center center NN cord-006870-f5w6fw6q 531 5 care care NN cord-006870-f5w6fw6q 531 6 among among IN cord-006870-f5w6fw6q 531 7 geriatric geriatric JJ cord-006870-f5w6fw6q 531 8 transfer transfer NN cord-006870-f5w6fw6q 531 9 patients patient NNS cord-006870-f5w6fw6q 531 10 with with IN cord-006870-f5w6fw6q 531 11 TBI TBI NNP cord-006870-f5w6fw6q 531 12 . . . cord-006870-f5w6fw6q 532 1 We -PRON- PRP cord-006870-f5w6fw6q 532 2 conducted conduct VBD cord-006870-f5w6fw6q 532 3 a a DT cord-006870-f5w6fw6q 532 4 secondary secondary JJ cord-006870-f5w6fw6q 532 5 analysis analysis NN cord-006870-f5w6fw6q 532 6 on on IN cord-006870-f5w6fw6q 532 7 a a DT cord-006870-f5w6fw6q 532 8 sub sub NN cord-006870-f5w6fw6q 532 9 - - JJ cord-006870-f5w6fw6q 532 10 cohort cohort NN cord-006870-f5w6fw6q 532 11 from from IN cord-006870-f5w6fw6q 532 12 a a DT cord-006870-f5w6fw6q 532 13 prospective prospective JJ cord-006870-f5w6fw6q 532 14 multi multi JJ cord-006870-f5w6fw6q 532 15 - - JJ cord-006870-f5w6fw6q 532 16 center center JJ cord-006870-f5w6fw6q 532 17 study study NN cord-006870-f5w6fw6q 532 18 focusing focus VBG cord-006870-f5w6fw6q 532 19 on on IN cord-006870-f5w6fw6q 532 20 ambulance ambulance NN cord-006870-f5w6fw6q 532 21 and and CC cord-006870-f5w6fw6q 532 22 emergency emergency NN cord-006870-f5w6fw6q 532 23 department department NN cord-006870-f5w6fw6q 532 24 ( ( -LRB- cord-006870-f5w6fw6q 532 25 ED ED NNP cord-006870-f5w6fw6q 532 26 ) ) -RRB- cord-006870-f5w6fw6q 532 27 care care NN cord-006870-f5w6fw6q 532 28 of of IN cord-006870-f5w6fw6q 532 29 injured injure VBN cord-006870-f5w6fw6q 532 30 older old JJR cord-006870-f5w6fw6q 532 31 adults adult NNS cord-006870-f5w6fw6q 532 32 transported transport VBN cord-006870-f5w6fw6q 532 33 via via IN cord-006870-f5w6fw6q 532 34 ambulance ambulance NN cord-006870-f5w6fw6q 532 35 . . . cord-006870-f5w6fw6q 533 1 The the DT cord-006870-f5w6fw6q 533 2 current current JJ cord-006870-f5w6fw6q 533 3 analysis analysis NN cord-006870-f5w6fw6q 533 4 focused focus VBN cord-006870-f5w6fw6q 533 5 on on IN cord-006870-f5w6fw6q 533 6 TBI TBI NNP cord-006870-f5w6fw6q 533 7 patients patient NNS cord-006870-f5w6fw6q 533 8 transferred transfer VBN cord-006870-f5w6fw6q 533 9 to to IN cord-006870-f5w6fw6q 533 10 the the DT cord-006870-f5w6fw6q 533 11 region region NN cord-006870-f5w6fw6q 533 12 's 's POS cord-006870-f5w6fw6q 533 13 Level Level NNP cord-006870-f5w6fw6q 533 14 I I NNP cord-006870-f5w6fw6q 533 15 trauma trauma NN cord-006870-f5w6fw6q 533 16 center center NN cord-006870-f5w6fw6q 533 17 from from IN cord-006870-f5w6fw6q 533 18 another another DT cord-006870-f5w6fw6q 533 19 hospital hospital NN cord-006870-f5w6fw6q 533 20 . . . cord-006870-f5w6fw6q 534 1 Transfer transfer NN cord-006870-f5w6fw6q 534 2 paperwork paperwork NN cord-006870-f5w6fw6q 534 3 from from IN cord-006870-f5w6fw6q 534 4 the the DT cord-006870-f5w6fw6q 534 5 originating originate VBG cord-006870-f5w6fw6q 534 6 hospital hospital NN cord-006870-f5w6fw6q 534 7 was be VBD cord-006870-f5w6fw6q 534 8 reviewed review VBN cord-006870-f5w6fw6q 534 9 and and CC cord-006870-f5w6fw6q 534 10 we -PRON- PRP cord-006870-f5w6fw6q 534 11 conducted conduct VBD cord-006870-f5w6fw6q 534 12 a a DT cord-006870-f5w6fw6q 534 13 detailed detailed JJ cord-006870-f5w6fw6q 534 14 medical medical JJ cord-006870-f5w6fw6q 534 15 record record NN cord-006870-f5w6fw6q 534 16 abstraction abstraction NN cord-006870-f5w6fw6q 534 17 , , , cord-006870-f5w6fw6q 534 18 including include VBG cord-006870-f5w6fw6q 534 19 computed compute VBN cord-006870-f5w6fw6q 534 20 tomography tomography NN cord-006870-f5w6fw6q 534 21 ( ( -LRB- cord-006870-f5w6fw6q 534 22 CT CT NNP cord-006870-f5w6fw6q 534 23 ) ) -RRB- cord-006870-f5w6fw6q 534 24 findings finding NNS cord-006870-f5w6fw6q 534 25 , , , cord-006870-f5w6fw6q 534 26 procedures procedure NNS cord-006870-f5w6fw6q 534 27 , , , cord-006870-f5w6fw6q 534 28 length length NN cord-006870-f5w6fw6q 534 29 of of IN cord-006870-f5w6fw6q 534 30 stay stay NN cord-006870-f5w6fw6q 534 31 ( ( -LRB- cord-006870-f5w6fw6q 534 32 LOS LOS NNP cord-006870-f5w6fw6q 534 33 ) ) -RRB- cord-006870-f5w6fw6q 534 34 , , , cord-006870-f5w6fw6q 534 35 and and CC cord-006870-f5w6fw6q 534 36 ED ED NNP cord-006870-f5w6fw6q 534 37 disposition disposition NN cord-006870-f5w6fw6q 534 38 . . . cord-006870-f5w6fw6q 535 1 Data datum NNS cord-006870-f5w6fw6q 535 2 were be VBD cord-006870-f5w6fw6q 535 3 collected collect VBN cord-006870-f5w6fw6q 535 4 on on IN cord-006870-f5w6fw6q 535 5 205 205 CD cord-006870-f5w6fw6q 535 6 transfer transfer NN cord-006870-f5w6fw6q 535 7 patients patient NNS cord-006870-f5w6fw6q 535 8 . . . cord-006870-f5w6fw6q 536 1 Thirty thirty CD cord-006870-f5w6fw6q 536 2 had have VBD cord-006870-f5w6fw6q 536 3 confirmed confirm VBN cord-006870-f5w6fw6q 536 4 abnormalities abnormality NNS cord-006870-f5w6fw6q 536 5 on on IN cord-006870-f5w6fw6q 536 6 head head NN cord-006870-f5w6fw6q 536 7 CT CT NNP cord-006870-f5w6fw6q 536 8 ( ( -LRB- cord-006870-f5w6fw6q 536 9 14.6 14.6 CD cord-006870-f5w6fw6q 536 10 % % NN cord-006870-f5w6fw6q 536 11 ) ) -RRB- cord-006870-f5w6fw6q 536 12 . . . cord-006870-f5w6fw6q 537 1 The the DT cord-006870-f5w6fw6q 537 2 mean mean JJ cord-006870-f5w6fw6q 537 3 age age NN cord-006870-f5w6fw6q 537 4 was be VBD cord-006870-f5w6fw6q 537 5 78 78 CD cord-006870-f5w6fw6q 537 6 years year NNS cord-006870-f5w6fw6q 538 1 ( ( -LRB- cord-006870-f5w6fw6q 538 2 range range NN cord-006870-f5w6fw6q 538 3 : : : cord-006870-f5w6fw6q 538 4 55 55 CD cord-006870-f5w6fw6q 538 5 - - SYM cord-006870-f5w6fw6q 538 6 91 91 CD cord-006870-f5w6fw6q 538 7 ) ) -RRB- cord-006870-f5w6fw6q 538 8 , , , cord-006870-f5w6fw6q 538 9 57 57 CD cord-006870-f5w6fw6q 538 10 % % NN cord-006870-f5w6fw6q 538 11 female female NN cord-006870-f5w6fw6q 538 12 , , , cord-006870-f5w6fw6q 538 13 and and CC cord-006870-f5w6fw6q 538 14 the the DT cord-006870-f5w6fw6q 538 15 most most RBS cord-006870-f5w6fw6q 538 16 frequent frequent JJ cord-006870-f5w6fw6q 538 17 mechanism mechanism NN cord-006870-f5w6fw6q 538 18 of of IN cord-006870-f5w6fw6q 538 19 injury injury NN cord-006870-f5w6fw6q 538 20 was be VBD cord-006870-f5w6fw6q 538 21 falls fall NNS cord-006870-f5w6fw6q 538 22 ( ( -LRB- cord-006870-f5w6fw6q 538 23 93 93 CD cord-006870-f5w6fw6q 538 24 % % NN cord-006870-f5w6fw6q 538 25 ) ) -RRB- cord-006870-f5w6fw6q 538 26 . . . cord-006870-f5w6fw6q 539 1 Average average JJ cord-006870-f5w6fw6q 539 2 LOS LOS NNP cord-006870-f5w6fw6q 539 3 was be VBD cord-006870-f5w6fw6q 539 4 13.5 13.5 CD cord-006870-f5w6fw6q 539 5 days day NNS cord-006870-f5w6fw6q 539 6 ( ( -LRB- cord-006870-f5w6fw6q 539 7 range range NN cord-006870-f5w6fw6q 539 8 : : : cord-006870-f5w6fw6q 539 9 0 0 CD cord-006870-f5w6fw6q 539 10 - - SYM cord-006870-f5w6fw6q 539 11 230 230 CD cord-006870-f5w6fw6q 539 12 , , , cord-006870-f5w6fw6q 539 13 median median JJ cord-006870-f5w6fw6q 539 14 LOS LOS NNP cord-006870-f5w6fw6q 539 15 4.5 4.5 CD cord-006870-f5w6fw6q 539 16 ) ) -RRB- cord-006870-f5w6fw6q 539 17 , , , cord-006870-f5w6fw6q 539 18 with with IN cord-006870-f5w6fw6q 539 19 8 8 CD cord-006870-f5w6fw6q 539 20 patients patient NNS cord-006870-f5w6fw6q 539 21 staying stay VBG cord-006870-f5w6fw6q 539 22 one one CD cord-006870-f5w6fw6q 539 23 day day NN cord-006870-f5w6fw6q 539 24 or or CC cord-006870-f5w6fw6q 539 25 less less JJR cord-006870-f5w6fw6q 539 26 . . . cord-006870-f5w6fw6q 540 1 CT CT NNP cord-006870-f5w6fw6q 540 2 findings finding NNS cord-006870-f5w6fw6q 540 3 included include VBD cord-006870-f5w6fw6q 540 4 subdural subdural JJ cord-006870-f5w6fw6q 540 5 hematoma hematoma NN cord-006870-f5w6fw6q 540 6 ( ( -LRB- cord-006870-f5w6fw6q 540 7 60 60 CD cord-006870-f5w6fw6q 540 8 % % NN cord-006870-f5w6fw6q 540 9 ) ) -RRB- cord-006870-f5w6fw6q 540 10 , , , cord-006870-f5w6fw6q 540 11 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 540 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 540 13 ( ( -LRB- cord-006870-f5w6fw6q 540 14 50 50 CD cord-006870-f5w6fw6q 540 15 % % NN cord-006870-f5w6fw6q 540 16 ) ) -RRB- cord-006870-f5w6fw6q 540 17 , , , cord-006870-f5w6fw6q 540 18 and and CC cord-006870-f5w6fw6q 540 19 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 540 20 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 540 21 ( ( -LRB- cord-006870-f5w6fw6q 540 22 36.7 36.7 CD cord-006870-f5w6fw6q 540 23 % % NN cord-006870-f5w6fw6q 540 24 ) ) -RRB- cord-006870-f5w6fw6q 540 25 . . . cord-006870-f5w6fw6q 541 1 Five five CD cord-006870-f5w6fw6q 541 2 patients patient NNS cord-006870-f5w6fw6q 541 3 required require VBD cord-006870-f5w6fw6q 541 4 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 541 5 intervention intervention NN cord-006870-f5w6fw6q 541 6 ( ( -LRB- cord-006870-f5w6fw6q 541 7 17 17 CD cord-006870-f5w6fw6q 541 8 % % NN cord-006870-f5w6fw6q 541 9 ) ) -RRB- cord-006870-f5w6fw6q 541 10 , , , cord-006870-f5w6fw6q 541 11 eight eight CD cord-006870-f5w6fw6q 541 12 required require VBD cord-006870-f5w6fw6q 541 13 ICU ICU NNP cord-006870-f5w6fw6q 541 14 admission admission NN cord-006870-f5w6fw6q 541 15 ( ( -LRB- cord-006870-f5w6fw6q 541 16 27 27 CD cord-006870-f5w6fw6q 541 17 % % NN cord-006870-f5w6fw6q 541 18 ) ) -RRB- cord-006870-f5w6fw6q 541 19 , , , cord-006870-f5w6fw6q 541 20 two two CD cord-006870-f5w6fw6q 541 21 were be VBD cord-006870-f5w6fw6q 541 22 discharged discharge VBN cord-006870-f5w6fw6q 541 23 from from IN cord-006870-f5w6fw6q 541 24 the the DT cord-006870-f5w6fw6q 541 25 ED ED NNP cord-006870-f5w6fw6q 541 26 ( ( -LRB- cord-006870-f5w6fw6q 541 27 7 7 CD cord-006870-f5w6fw6q 541 28 % % NN cord-006870-f5w6fw6q 541 29 ) ) -RRB- cord-006870-f5w6fw6q 541 30 , , , cord-006870-f5w6fw6q 541 31 and and CC cord-006870-f5w6fw6q 541 32 two two CD cord-006870-f5w6fw6q 541 33 transitioned transition VBD cord-006870-f5w6fw6q 541 34 to to IN cord-006870-f5w6fw6q 541 35 inpatient inpatient JJ cord-006870-f5w6fw6q 541 36 hospice hospice NN cord-006870-f5w6fw6q 541 37 ( ( -LRB- cord-006870-f5w6fw6q 541 38 7 7 CD cord-006870-f5w6fw6q 541 39 % % NN cord-006870-f5w6fw6q 541 40 ) ) -RRB- cord-006870-f5w6fw6q 541 41 . . . cord-006870-f5w6fw6q 542 1 TBI TBI NNP cord-006870-f5w6fw6q 542 2 is be VBZ cord-006870-f5w6fw6q 542 3 a a DT cord-006870-f5w6fw6q 542 4 frequent frequent JJ cord-006870-f5w6fw6q 542 5 cause cause NN cord-006870-f5w6fw6q 542 6 of of IN cord-006870-f5w6fw6q 542 7 transfers transfer NNS cord-006870-f5w6fw6q 542 8 to to IN cord-006870-f5w6fw6q 542 9 trauma trauma NN cord-006870-f5w6fw6q 542 10 centers center NNS cord-006870-f5w6fw6q 542 11 . . . cord-006870-f5w6fw6q 543 1 In in IN cord-006870-f5w6fw6q 543 2 our -PRON- PRP$ cord-006870-f5w6fw6q 543 3 sample sample NN cord-006870-f5w6fw6q 543 4 , , , cord-006870-f5w6fw6q 543 5 admission admission NN cord-006870-f5w6fw6q 543 6 occurred occur VBD cord-006870-f5w6fw6q 543 7 in in IN cord-006870-f5w6fw6q 543 8 the the DT cord-006870-f5w6fw6q 543 9 majority majority NN cord-006870-f5w6fw6q 543 10 of of IN cord-006870-f5w6fw6q 543 11 patients patient NNS cord-006870-f5w6fw6q 543 12 , , , cord-006870-f5w6fw6q 543 13 but but CC cord-006870-f5w6fw6q 543 14 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 543 15 intervention intervention NN cord-006870-f5w6fw6q 543 16 was be VBD cord-006870-f5w6fw6q 543 17 less less RBR cord-006870-f5w6fw6q 543 18 common common JJ cord-006870-f5w6fw6q 543 19 . . . cord-006870-f5w6fw6q 544 1 However however RB cord-006870-f5w6fw6q 544 2 , , , cord-006870-f5w6fw6q 544 3 for for IN cord-006870-f5w6fw6q 544 4 appropriately appropriately RB cord-006870-f5w6fw6q 544 5 selected select VBN cord-006870-f5w6fw6q 544 6 patients patient NNS cord-006870-f5w6fw6q 544 7 , , , cord-006870-f5w6fw6q 544 8 strategies strategy NNS cord-006870-f5w6fw6q 544 9 such such JJ cord-006870-f5w6fw6q 544 10 as as IN cord-006870-f5w6fw6q 544 11 telemedicine telemedicine NN cord-006870-f5w6fw6q 544 12 may may MD cord-006870-f5w6fw6q 544 13 reduce reduce VB cord-006870-f5w6fw6q 544 14 transfers transfer NNS cord-006870-f5w6fw6q 544 15 thus thus RB cord-006870-f5w6fw6q 544 16 saving save VBG cord-006870-f5w6fw6q 544 17 resources resource NNS cord-006870-f5w6fw6q 544 18 and and CC cord-006870-f5w6fw6q 544 19 improving improve VBG cord-006870-f5w6fw6q 544 20 continuity continuity NN cord-006870-f5w6fw6q 544 21 of of IN cord-006870-f5w6fw6q 544 22 care care NN cord-006870-f5w6fw6q 544 23 for for IN cord-006870-f5w6fw6q 544 24 patients patient NNS cord-006870-f5w6fw6q 544 25 and and CC cord-006870-f5w6fw6q 544 26 their -PRON- PRP$ cord-006870-f5w6fw6q 544 27 families family NNS cord-006870-f5w6fw6q 544 28 . . . cord-006870-f5w6fw6q 545 1 This this DT cord-006870-f5w6fw6q 545 2 is be VBZ cord-006870-f5w6fw6q 545 3 an an DT cord-006870-f5w6fw6q 545 4 area area NN cord-006870-f5w6fw6q 545 5 in in IN cord-006870-f5w6fw6q 545 6 which which WDT cord-006870-f5w6fw6q 545 7 future future JJ cord-006870-f5w6fw6q 545 8 research research NN cord-006870-f5w6fw6q 545 9 is be VBZ cord-006870-f5w6fw6q 545 10 warranted warrant VBN cord-006870-f5w6fw6q 545 11 . . . cord-006870-f5w6fw6q 546 1 The the DT cord-006870-f5w6fw6q 546 2 prospects prospect NNS cord-006870-f5w6fw6q 546 3 and and CC cord-006870-f5w6fw6q 546 4 timing timing NN cord-006870-f5w6fw6q 546 5 of of IN cord-006870-f5w6fw6q 546 6 decannulation decannulation NN cord-006870-f5w6fw6q 546 7 may may MD cord-006870-f5w6fw6q 546 8 affect affect VB cord-006870-f5w6fw6q 546 9 surrogate surrogate JJ cord-006870-f5w6fw6q 546 10 decision decision NN cord-006870-f5w6fw6q 546 11 making make VBG cord-006870-f5w6fw6q 546 12 regarding regard VBG cord-006870-f5w6fw6q 546 13 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 546 14 for for IN cord-006870-f5w6fw6q 546 15 traumatic traumatic JJ cord-006870-f5w6fw6q 546 16 brain brain NN cord-006870-f5w6fw6q 546 17 injury injury NN cord-006870-f5w6fw6q 546 18 ( ( -LRB- cord-006870-f5w6fw6q 546 19 TBI TBI NNP cord-006870-f5w6fw6q 546 20 ) ) -RRB- cord-006870-f5w6fw6q 546 21 patients patient NNS cord-006870-f5w6fw6q 546 22 , , , cord-006870-f5w6fw6q 546 23 yet yet CC cord-006870-f5w6fw6q 546 24 predictors predictor NNS cord-006870-f5w6fw6q 546 25 of of IN cord-006870-f5w6fw6q 546 26 decannulation decannulation NN cord-006870-f5w6fw6q 546 27 are be VBP cord-006870-f5w6fw6q 546 28 unknown unknown JJ cord-006870-f5w6fw6q 546 29 . . . cord-006870-f5w6fw6q 547 1 Methods method NNS cord-006870-f5w6fw6q 547 2 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 547 3 admitted admit VBD cord-006870-f5w6fw6q 547 4 to to IN cord-006870-f5w6fw6q 547 5 an an DT cord-006870-f5w6fw6q 547 6 affiliated affiliated JJ cord-006870-f5w6fw6q 547 7 acute acute JJ cord-006870-f5w6fw6q 547 8 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 547 9 hospital hospital NN cord-006870-f5w6fw6q 547 10 between between IN cord-006870-f5w6fw6q 547 11 January January NNP cord-006870-f5w6fw6q 547 12 2014 2014 CD cord-006870-f5w6fw6q 547 13 and and CC cord-006870-f5w6fw6q 547 14 December December NNP cord-006870-f5w6fw6q 547 15 2014 2014 CD cord-006870-f5w6fw6q 547 16 . . . cord-006870-f5w6fw6q 548 1 Patients patient NNS cord-006870-f5w6fw6q 548 2 who who WP cord-006870-f5w6fw6q 548 3 had have VBD cord-006870-f5w6fw6q 548 4 life life NN cord-006870-f5w6fw6q 548 5 - - HYPH cord-006870-f5w6fw6q 548 6 sustaining sustain VBG cord-006870-f5w6fw6q 548 7 measures measure NNS cord-006870-f5w6fw6q 548 8 withdrawn withdraw VBN cord-006870-f5w6fw6q 548 9 were be VBD cord-006870-f5w6fw6q 548 10 excluded exclude VBN cord-006870-f5w6fw6q 548 11 . . . cord-006870-f5w6fw6q 549 1 Admission admission NN cord-006870-f5w6fw6q 549 2 data datum NNS cord-006870-f5w6fw6q 549 3 , , , cord-006870-f5w6fw6q 549 4 including include VBG cord-006870-f5w6fw6q 549 5 injury injury NN cord-006870-f5w6fw6q 549 6 characteristics characteristic NNS cord-006870-f5w6fw6q 549 7 and and CC cord-006870-f5w6fw6q 549 8 presence presence NN cord-006870-f5w6fw6q 549 9 of of IN cord-006870-f5w6fw6q 549 10 lung lung NN cord-006870-f5w6fw6q 549 11 injury injury NN cord-006870-f5w6fw6q 549 12 on on IN cord-006870-f5w6fw6q 549 13 initial initial JJ cord-006870-f5w6fw6q 549 14 chest chest NN cord-006870-f5w6fw6q 549 15 X X NNP cord-006870-f5w6fw6q 549 16 - - NNP cord-006870-f5w6fw6q 549 17 Ray Ray NNP cord-006870-f5w6fw6q 549 18 , , , cord-006870-f5w6fw6q 549 19 and and CC cord-006870-f5w6fw6q 549 20 inpatient inpatient JJ cord-006870-f5w6fw6q 549 21 complications complication NNS cord-006870-f5w6fw6q 549 22 were be VBD cord-006870-f5w6fw6q 549 23 compared compare VBN cord-006870-f5w6fw6q 549 24 . . . cord-006870-f5w6fw6q 550 1 Patients patient NNS cord-006870-f5w6fw6q 550 2 were be VBD cord-006870-f5w6fw6q 550 3 followed follow VBN cord-006870-f5w6fw6q 550 4 throughout throughout IN cord-006870-f5w6fw6q 550 5 rehab rehab NN cord-006870-f5w6fw6q 550 6 and and CC cord-006870-f5w6fw6q 550 7 to to IN cord-006870-f5w6fw6q 550 8 the the DT cord-006870-f5w6fw6q 550 9 point point NN cord-006870-f5w6fw6q 550 10 of of IN cord-006870-f5w6fw6q 550 11 decannulation decannulation NN cord-006870-f5w6fw6q 550 12 . . . cord-006870-f5w6fw6q 551 1 Patients patient NNS cord-006870-f5w6fw6q 551 2 lost lose VBD cord-006870-f5w6fw6q 551 3 to to TO cord-006870-f5w6fw6q 551 4 follow follow VB cord-006870-f5w6fw6q 551 5 up up RP cord-006870-f5w6fw6q 551 6 were be VBD cord-006870-f5w6fw6q 551 7 eliminated eliminate VBN cord-006870-f5w6fw6q 551 8 from from IN cord-006870-f5w6fw6q 551 9 analysis analysis NN cord-006870-f5w6fw6q 551 10 . . . cord-006870-f5w6fw6q 552 1 Time time NN cord-006870-f5w6fw6q 552 2 of of IN cord-006870-f5w6fw6q 552 3 decannulation decannulation NN cord-006870-f5w6fw6q 552 4 was be VBD cord-006870-f5w6fw6q 552 5 verified verify VBN cord-006870-f5w6fw6q 552 6 by by IN cord-006870-f5w6fw6q 552 7 inpatient inpatient JJ cord-006870-f5w6fw6q 552 8 physician physician NN cord-006870-f5w6fw6q 552 9 notes note NNS cord-006870-f5w6fw6q 552 10 . . . cord-006870-f5w6fw6q 553 1 A a DT cord-006870-f5w6fw6q 553 2 Cox Cox NNP cord-006870-f5w6fw6q 553 3 Proportional Proportional NNP cord-006870-f5w6fw6q 553 4 Hazards Hazards NNP cord-006870-f5w6fw6q 553 5 model model NN cord-006870-f5w6fw6q 553 6 was be VBD cord-006870-f5w6fw6q 553 7 created create VBN cord-006870-f5w6fw6q 553 8 to to TO cord-006870-f5w6fw6q 553 9 determine determine VB cord-006870-f5w6fw6q 553 10 factors factor NNS cord-006870-f5w6fw6q 553 11 associated associate VBN cord-006870-f5w6fw6q 553 12 with with IN cord-006870-f5w6fw6q 553 13 the the DT cord-006870-f5w6fw6q 553 14 time time NN cord-006870-f5w6fw6q 553 15 to to IN cord-006870-f5w6fw6q 553 16 decannulation decannulation NN cord-006870-f5w6fw6q 553 17 and and CC cord-006870-f5w6fw6q 553 18 reported report VBD cord-006870-f5w6fw6q 553 19 as as IN cord-006870-f5w6fw6q 553 20 hazard hazard NN cord-006870-f5w6fw6q 553 21 ratios ratio NNS cord-006870-f5w6fw6q 553 22 ( ( -LRB- cord-006870-f5w6fw6q 553 23 HR HR NNP cord-006870-f5w6fw6q 553 24 ) ) -RRB- cord-006870-f5w6fw6q 553 25 . . . cord-006870-f5w6fw6q 554 1 There there EX cord-006870-f5w6fw6q 554 2 were be VBD cord-006870-f5w6fw6q 554 3 209 209 CD cord-006870-f5w6fw6q 554 4 TBI TBI NNP cord-006870-f5w6fw6q 554 5 patients patient NNS cord-006870-f5w6fw6q 554 6 admitted admit VBD cord-006870-f5w6fw6q 554 7 to to IN cord-006870-f5w6fw6q 554 8 the the DT cord-006870-f5w6fw6q 554 9 ICU ICU NNP cord-006870-f5w6fw6q 554 10 during during IN cord-006870-f5w6fw6q 554 11 study study NN cord-006870-f5w6fw6q 554 12 period period NN cord-006870-f5w6fw6q 554 13 and and CC cord-006870-f5w6fw6q 554 14 94 94 CD cord-006870-f5w6fw6q 554 15 ( ( -LRB- cord-006870-f5w6fw6q 554 16 79 79 CD cord-006870-f5w6fw6q 554 17 % % NN cord-006870-f5w6fw6q 554 18 men man NNS cord-006870-f5w6fw6q 554 19 , , , cord-006870-f5w6fw6q 554 20 mean mean VB cord-006870-f5w6fw6q 555 1 46 46 CD cord-006870-f5w6fw6q 555 2 yearsold yearsold NN cord-006870-f5w6fw6q 555 3 , , , cord-006870-f5w6fw6q 555 4 median median JJ cord-006870-f5w6fw6q 555 5 GCS GCS NNP cord-006870-f5w6fw6q 555 6 7 7 CD cord-006870-f5w6fw6q 555 7 ) ) -RRB- cord-006870-f5w6fw6q 555 8 underwent undergo VBD cord-006870-f5w6fw6q 555 9 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 555 10 after after IN cord-006870-f5w6fw6q 555 11 10 10 CD cord-006870-f5w6fw6q 555 12 ± ± CD cord-006870-f5w6fw6q 555 13 6 6 CD cord-006870-f5w6fw6q 555 14 days day NNS cord-006870-f5w6fw6q 555 15 of of IN cord-006870-f5w6fw6q 555 16 intubation intubation NN cord-006870-f5w6fw6q 555 17 , , , cord-006870-f5w6fw6q 555 18 of of IN cord-006870-f5w6fw6q 555 19 which which WDT cord-006870-f5w6fw6q 555 20 79 79 CD cord-006870-f5w6fw6q 555 21 were be VBD cord-006870-f5w6fw6q 555 22 followed follow VBN cord-006870-f5w6fw6q 555 23 throughout throughout IN cord-006870-f5w6fw6q 555 24 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 555 25 . . . cord-006870-f5w6fw6q 556 1 Overall overall JJ cord-006870-f5w6fw6q 556 2 cannulation cannulation NN cord-006870-f5w6fw6q 556 3 time time NN cord-006870-f5w6fw6q 556 4 was be VBD cord-006870-f5w6fw6q 556 5 37 37 CD cord-006870-f5w6fw6q 556 6 ( ( -LRB- cord-006870-f5w6fw6q 556 7 29 29 CD cord-006870-f5w6fw6q 556 8 - - SYM cord-006870-f5w6fw6q 556 9 65 65 CD cord-006870-f5w6fw6q 556 10 ) ) -RRB- cord-006870-f5w6fw6q 556 11 days day NNS cord-006870-f5w6fw6q 556 12 . . . cord-006870-f5w6fw6q 557 1 55 55 CD cord-006870-f5w6fw6q 557 2 ( ( -LRB- cord-006870-f5w6fw6q 557 3 70 70 CD cord-006870-f5w6fw6q 557 4 % % NN cord-006870-f5w6fw6q 557 5 ) ) -RRB- cord-006870-f5w6fw6q 557 6 patients patient NNS cord-006870-f5w6fw6q 557 7 had have VBD cord-006870-f5w6fw6q 557 8 their -PRON- PRP$ cord-006870-f5w6fw6q 557 9 trach trach NN cord-006870-f5w6fw6q 557 10 removed remove VBN cord-006870-f5w6fw6q 557 11 prior prior RB cord-006870-f5w6fw6q 557 12 to to IN cord-006870-f5w6fw6q 557 13 discharge discharge NN cord-006870-f5w6fw6q 557 14 from from IN cord-006870-f5w6fw6q 557 15 rehab rehab NN cord-006870-f5w6fw6q 557 16 after after IN cord-006870-f5w6fw6q 557 17 35 35 CD cord-006870-f5w6fw6q 557 18 ( ( -LRB- cord-006870-f5w6fw6q 557 19 27 27 CD cord-006870-f5w6fw6q 557 20 - - SYM cord-006870-f5w6fw6q 557 21 49 49 CD cord-006870-f5w6fw6q 557 22 ) ) -RRB- cord-006870-f5w6fw6q 557 23 days day NNS cord-006870-f5w6fw6q 557 24 of of IN cord-006870-f5w6fw6q 557 25 cannulation cannulation NN cord-006870-f5w6fw6q 557 26 . . . cord-006870-f5w6fw6q 558 1 In in IN cord-006870-f5w6fw6q 558 2 a a DT cord-006870-f5w6fw6q 558 3 Cox Cox NNP cord-006870-f5w6fw6q 558 4 Proportional Proportional NNP cord-006870-f5w6fw6q 558 5 model model NN cord-006870-f5w6fw6q 558 6 adjusting adjust VBG cord-006870-f5w6fw6q 558 7 for for IN cord-006870-f5w6fw6q 558 8 sex sex NN cord-006870-f5w6fw6q 558 9 , , , cord-006870-f5w6fw6q 558 10 reintubation reintubation NN cord-006870-f5w6fw6q 558 11 , , , cord-006870-f5w6fw6q 558 12 aspiration aspiration NN cord-006870-f5w6fw6q 558 13 pneumonitis pneumonitis NN cord-006870-f5w6fw6q 558 14 , , , cord-006870-f5w6fw6q 558 15 and and CC cord-006870-f5w6fw6q 558 16 presence presence NN cord-006870-f5w6fw6q 558 17 of of IN cord-006870-f5w6fw6q 558 18 lung lung NN cord-006870-f5w6fw6q 558 19 injury injury NN cord-006870-f5w6fw6q 558 20 on on IN cord-006870-f5w6fw6q 558 21 admission admission NN cord-006870-f5w6fw6q 558 22 chest chest NN cord-006870-f5w6fw6q 558 23 X x NN cord-006870-f5w6fw6q 558 24 - - NN cord-006870-f5w6fw6q 558 25 ray ray NN cord-006870-f5w6fw6q 558 26 ; ; : cord-006870-f5w6fw6q 558 27 a a DT cord-006870-f5w6fw6q 558 28 higher high JJR cord-006870-f5w6fw6q 558 29 hospital hospital NN cord-006870-f5w6fw6q 558 30 discharge discharge NN cord-006870-f5w6fw6q 558 31 GCS GCS NNP cord-006870-f5w6fw6q 558 32 was be VBD cord-006870-f5w6fw6q 558 33 associated associate VBN cord-006870-f5w6fw6q 558 34 with with IN cord-006870-f5w6fw6q 558 35 a a DT cord-006870-f5w6fw6q 558 36 shorter short JJR cord-006870-f5w6fw6q 558 37 time time NN cord-006870-f5w6fw6q 558 38 to to IN cord-006870-f5w6fw6q 558 39 decannulation decannulation NN cord-006870-f5w6fw6q 558 40 ( ( -LRB- cord-006870-f5w6fw6q 558 41 HR HR NNP cord-006870-f5w6fw6q 558 42 , , , cord-006870-f5w6fw6q 558 43 1.147 1.147 CD cord-006870-f5w6fw6q 558 44 ; ; : cord-006870-f5w6fw6q 558 45 95 95 CD cord-006870-f5w6fw6q 558 46 % % NN cord-006870-f5w6fw6q 558 47 CI CI NNP cord-006870-f5w6fw6q 558 48 , , , cord-006870-f5w6fw6q 558 49 1.023 1.023 CD cord-006870-f5w6fw6q 558 50 - - SYM cord-006870-f5w6fw6q 558 51 1.286 1.286 CD cord-006870-f5w6fw6q 558 52 ; ; : cord-006870-f5w6fw6q 558 53 p p NN cord-006870-f5w6fw6q 558 54 = = SYM cord-006870-f5w6fw6q 558 55 .019 .019 CD cord-006870-f5w6fw6q 558 56 ) ) -RRB- cord-006870-f5w6fw6q 558 57 while while IN cord-006870-f5w6fw6q 558 58 patients patient NNS cord-006870-f5w6fw6q 558 59 who who WP cord-006870-f5w6fw6q 558 60 required require VBD cord-006870-f5w6fw6q 558 61 inpatient inpatient JJ cord-006870-f5w6fw6q 558 62 dialysis dialysis NN cord-006870-f5w6fw6q 558 63 had have VBD cord-006870-f5w6fw6q 558 64 a a DT cord-006870-f5w6fw6q 558 65 longer long JJR cord-006870-f5w6fw6q 558 66 time time NN cord-006870-f5w6fw6q 558 67 to to IN cord-006870-f5w6fw6q 558 68 decannulation decannulation NN cord-006870-f5w6fw6q 558 69 ( ( -LRB- cord-006870-f5w6fw6q 558 70 HR hr NN cord-006870-f5w6fw6q 558 71 : : : cord-006870-f5w6fw6q 558 72 0.281 0.281 CD cord-006870-f5w6fw6q 558 73 ; ; : cord-006870-f5w6fw6q 558 74 95 95 CD cord-006870-f5w6fw6q 558 75 % % NN cord-006870-f5w6fw6q 558 76 CI CI NNP cord-006870-f5w6fw6q 558 77 , , , cord-006870-f5w6fw6q 558 78 0.098 0.098 CD cord-006870-f5w6fw6q 558 79 - - SYM cord-006870-f5w6fw6q 558 80 0.803 0.803 CD cord-006870-f5w6fw6q 558 81 ; ; : cord-006870-f5w6fw6q 558 82 p p NN cord-006870-f5w6fw6q 558 83 = = SYM cord-006870-f5w6fw6q 558 84 .018 .018 CD cord-006870-f5w6fw6q 558 85 ) ) -RRB- cord-006870-f5w6fw6q 558 86 . . . cord-006870-f5w6fw6q 559 1 The the DT cord-006870-f5w6fw6q 559 2 majority majority NN cord-006870-f5w6fw6q 559 3 of of IN cord-006870-f5w6fw6q 559 4 TBI TBI NNP cord-006870-f5w6fw6q 559 5 patients patient NNS cord-006870-f5w6fw6q 559 6 that that WDT cord-006870-f5w6fw6q 559 7 require require VBP cord-006870-f5w6fw6q 559 8 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 559 9 will will MD cord-006870-f5w6fw6q 559 10 be be VB cord-006870-f5w6fw6q 559 11 decannulated decannulate VBN cord-006870-f5w6fw6q 559 12 prior prior RB cord-006870-f5w6fw6q 559 13 to to IN cord-006870-f5w6fw6q 559 14 discharge discharge NN cord-006870-f5w6fw6q 559 15 from from IN cord-006870-f5w6fw6q 559 16 rehab rehab NN cord-006870-f5w6fw6q 559 17 . . . cord-006870-f5w6fw6q 560 1 Longer long JJR cord-006870-f5w6fw6q 560 2 durations duration NNS cord-006870-f5w6fw6q 560 3 of of IN cord-006870-f5w6fw6q 560 4 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 560 5 cannulatio cannulatio NNP cord-006870-f5w6fw6q 560 6 hospital hospital NN cord-006870-f5w6fw6q 560 7 discharge discharge NN cord-006870-f5w6fw6q 560 8 and and CC cord-006870-f5w6fw6q 560 9 those those DT cord-006870-f5w6fw6q 560 10 that that WDT cord-006870-f5w6fw6q 560 11 receive receive VBP cord-006870-f5w6fw6q 560 12 inpatient inpatient JJ cord-006870-f5w6fw6q 560 13 dialysis dialysis NN cord-006870-f5w6fw6q 560 14 . . . cord-006870-f5w6fw6q 561 1 Goal Goal NNP cord-006870-f5w6fw6q 561 2 Directed Directed NNP cord-006870-f5w6fw6q 561 3 Therapy Therapy NNP cord-006870-f5w6fw6q 561 4 ( ( -LRB- cord-006870-f5w6fw6q 561 5 GDT GDT NNP cord-006870-f5w6fw6q 561 6 ) ) -RRB- cord-006870-f5w6fw6q 561 7 is be VBZ cord-006870-f5w6fw6q 561 8 thought think VBN cord-006870-f5w6fw6q 561 9 to to TO cord-006870-f5w6fw6q 561 10 be be VB cord-006870-f5w6fw6q 561 11 associated associate VBN cord-006870-f5w6fw6q 561 12 with with IN cord-006870-f5w6fw6q 561 13 outcome outcome NN cord-006870-f5w6fw6q 561 14 after after IN cord-006870-f5w6fw6q 561 15 traumatic traumatic JJ cord-006870-f5w6fw6q 561 16 brain brain NN cord-006870-f5w6fw6q 561 17 injury injury NN cord-006870-f5w6fw6q 561 18 ( ( -LRB- cord-006870-f5w6fw6q 561 19 TBI TBI NNP cord-006870-f5w6fw6q 561 20 ) ) -RRB- cord-006870-f5w6fw6q 561 21 . . . cord-006870-f5w6fw6q 562 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 562 2 team team NN cord-006870-f5w6fw6q 562 3 applied apply VBD cord-006870-f5w6fw6q 562 4 GDT GDT NNP cord-006870-f5w6fw6q 562 5 to to TO cord-006870-f5w6fw6q 562 6 standardize standardize VB cord-006870-f5w6fw6q 562 7 care care NN cord-006870-f5w6fw6q 562 8 in in IN cord-006870-f5w6fw6q 562 9 patients patient NNS cord-006870-f5w6fw6q 562 10 with with IN cord-006870-f5w6fw6q 562 11 moderate moderate JJ cord-006870-f5w6fw6q 562 12 to to IN cord-006870-f5w6fw6q 562 13 severe severe JJ cord-006870-f5w6fw6q 562 14 TBI TBI NNP cord-006870-f5w6fw6q 562 15 , , , cord-006870-f5w6fw6q 562 16 who who WP cord-006870-f5w6fw6q 562 17 were be VBD cord-006870-f5w6fw6q 562 18 enrolled enrol VBN cord-006870-f5w6fw6q 562 19 in in IN cord-006870-f5w6fw6q 562 20 a a DT cord-006870-f5w6fw6q 562 21 large large JJ cord-006870-f5w6fw6q 562 22 multicenter multicenter JJ cord-006870-f5w6fw6q 562 23 clinical clinical JJ cord-006870-f5w6fw6q 562 24 trial trial NN cord-006870-f5w6fw6q 562 25 . . . cord-006870-f5w6fw6q 563 1 Physiologic physiologic JJ cord-006870-f5w6fw6q 563 2 goals goal NNS cord-006870-f5w6fw6q 563 3 were be VBD cord-006870-f5w6fw6q 563 4 defined define VBN cord-006870-f5w6fw6q 563 5 a a DT cord-006870-f5w6fw6q 563 6 priori priori FW cord-006870-f5w6fw6q 563 7 in in IN cord-006870-f5w6fw6q 563 8 order order NN cord-006870-f5w6fw6q 563 9 to to TO cord-006870-f5w6fw6q 563 10 standardize standardize VB cord-006870-f5w6fw6q 563 11 care care NN cord-006870-f5w6fw6q 563 12 across across IN cord-006870-f5w6fw6q 563 13 42 42 CD cord-006870-f5w6fw6q 563 14 sites site NNS cord-006870-f5w6fw6q 563 15 participating participate VBG cord-006870-f5w6fw6q 563 16 in in IN cord-006870-f5w6fw6q 563 17 the the DT cord-006870-f5w6fw6q 563 18 ProTECT ProTECT NNS cord-006870-f5w6fw6q 563 19 III iii CD cord-006870-f5w6fw6q 563 20 trial trial NN cord-006870-f5w6fw6q 563 21 . . . cord-006870-f5w6fw6q 564 1 Data datum NNS cord-006870-f5w6fw6q 564 2 were be VBD cord-006870-f5w6fw6q 564 3 collected collect VBN cord-006870-f5w6fw6q 564 4 hourly hourly RB cord-006870-f5w6fw6q 564 5 for for IN cord-006870-f5w6fw6q 564 6 all all DT cord-006870-f5w6fw6q 564 7 randomized randomized JJ cord-006870-f5w6fw6q 564 8 subjects subject NNS cord-006870-f5w6fw6q 564 9 ( ( -LRB- cord-006870-f5w6fw6q 564 10 n=882 n=882 NNP cord-006870-f5w6fw6q 564 11 ) ) -RRB- cord-006870-f5w6fw6q 564 12 . . . cord-006870-f5w6fw6q 565 1 Hours hour NNS cord-006870-f5w6fw6q 565 2 where where WRB cord-006870-f5w6fw6q 565 3 GDT GDT NNP cord-006870-f5w6fw6q 565 4 were be VBD cord-006870-f5w6fw6q 565 5 not not RB cord-006870-f5w6fw6q 565 6 achieved achieve VBN cord-006870-f5w6fw6q 565 7 were be VBD cord-006870-f5w6fw6q 565 8 classified classify VBN cord-006870-f5w6fw6q 565 9 as as IN cord-006870-f5w6fw6q 565 10 " " `` cord-006870-f5w6fw6q 565 11 transgressions transgression NNS cord-006870-f5w6fw6q 565 12 " " '' cord-006870-f5w6fw6q 565 13 . . . cord-006870-f5w6fw6q 566 1 These these DT cord-006870-f5w6fw6q 566 2 included include VBD cord-006870-f5w6fw6q 566 3 : : : cord-006870-f5w6fw6q 567 1 MAP1.4 MAP1.4 NNP cord-006870-f5w6fw6q 567 2 ; ; : cord-006870-f5w6fw6q 567 3 Platelets180mg Platelets180mg NNP cord-006870-f5w6fw6q 567 4 / / SYM cord-006870-f5w6fw6q 567 5 dl dl NN cord-006870-f5w6fw6q 567 6 ; ; : cord-006870-f5w6fw6q 567 7 and and CC cord-006870-f5w6fw6q 567 8 SBP180mmHg SBP180mmHg NNP cord-006870-f5w6fw6q 567 9 . . . cord-006870-f5w6fw6q 568 1 The the DT cord-006870-f5w6fw6q 568 2 proportion proportion NN cord-006870-f5w6fw6q 568 3 of of IN cord-006870-f5w6fw6q 568 4 hours hour NNS cord-006870-f5w6fw6q 568 5 spent spend VBN cord-006870-f5w6fw6q 568 6 in in IN cord-006870-f5w6fw6q 568 7 transgression transgression NN cord-006870-f5w6fw6q 568 8 was be VBD cord-006870-f5w6fw6q 568 9 calculated calculate VBN cord-006870-f5w6fw6q 568 10 for for IN cord-006870-f5w6fw6q 568 11 each each DT cord-006870-f5w6fw6q 568 12 parameter parameter NN cord-006870-f5w6fw6q 568 13 and and CC cord-006870-f5w6fw6q 568 14 grouped group VBN cord-006870-f5w6fw6q 568 15 by by IN cord-006870-f5w6fw6q 568 16 quartile quartile NN cord-006870-f5w6fw6q 568 17 . . . cord-006870-f5w6fw6q 569 1 Poor poor JJ cord-006870-f5w6fw6q 569 2 outcome outcome NN cord-006870-f5w6fw6q 569 3 was be VBD cord-006870-f5w6fw6q 569 4 defined define VBN cord-006870-f5w6fw6q 569 5 via via IN cord-006870-f5w6fw6q 569 6 stratified stratified JJ cord-006870-f5w6fw6q 569 7 dichotomy dichotomy NN cord-006870-f5w6fw6q 569 8 of of IN cord-006870-f5w6fw6q 569 9 the the DT cord-006870-f5w6fw6q 569 10 GOS GOS NNP cord-006870-f5w6fw6q 569 11 - - HYPH cord-006870-f5w6fw6q 569 12 E. E. NNP cord-006870-f5w6fw6q 569 13 Data Data NNP cord-006870-f5w6fw6q 569 14 were be VBD cord-006870-f5w6fw6q 569 15 adjudicated adjudicate VBN cord-006870-f5w6fw6q 569 16 electronically electronically RB cord-006870-f5w6fw6q 569 17 and and CC cord-006870-f5w6fw6q 569 18 via via IN cord-006870-f5w6fw6q 569 19 expert expert NN cord-006870-f5w6fw6q 569 20 review review NN cord-006870-f5w6fw6q 569 21 . . . cord-006870-f5w6fw6q 570 1 For for IN cord-006870-f5w6fw6q 570 2 each each DT cord-006870-f5w6fw6q 570 3 parameter parameter NN cord-006870-f5w6fw6q 570 4 , , , cord-006870-f5w6fw6q 570 5 the the DT cord-006870-f5w6fw6q 570 6 association association NN cord-006870-f5w6fw6q 570 7 between between IN cord-006870-f5w6fw6q 570 8 outcome outcome NN cord-006870-f5w6fw6q 570 9 and and CC cord-006870-f5w6fw6q 570 10 either either RB cord-006870-f5w6fw6q 570 11 ( ( -LRB- cord-006870-f5w6fw6q 570 12 1 1 LS cord-006870-f5w6fw6q 570 13 ) ) -RRB- cord-006870-f5w6fw6q 570 14 occurrence occurrence NN cord-006870-f5w6fw6q 570 15 of of IN cord-006870-f5w6fw6q 570 16 transgression transgression NN cord-006870-f5w6fw6q 570 17 or or CC cord-006870-f5w6fw6q 570 18 ( ( -LRB- cord-006870-f5w6fw6q 570 19 2 2 LS cord-006870-f5w6fw6q 570 20 ) ) -RRB- cord-006870-f5w6fw6q 570 21 cumulative cumulative JJ cord-006870-f5w6fw6q 570 22 duration duration NN cord-006870-f5w6fw6q 570 23 of of IN cord-006870-f5w6fw6q 570 24 transgression transgression NN cord-006870-f5w6fw6q 570 25 was be VBD cord-006870-f5w6fw6q 570 26 estimated estimate VBN cord-006870-f5w6fw6q 570 27 via via IN cord-006870-f5w6fw6q 570 28 logistic logistic JJ cord-006870-f5w6fw6q 570 29 regression regression NN cord-006870-f5w6fw6q 570 30 model model NN cord-006870-f5w6fw6q 570 31 , , , cord-006870-f5w6fw6q 570 32 and and CC cord-006870-f5w6fw6q 570 33 backward backward JJ cord-006870-f5w6fw6q 570 34 selection selection NN cord-006870-f5w6fw6q 570 35 was be VBD cord-006870-f5w6fw6q 570 36 used use VBN cord-006870-f5w6fw6q 570 37 to to TO cord-006870-f5w6fw6q 570 38 identify identify VB cord-006870-f5w6fw6q 570 39 the the DT cord-006870-f5w6fw6q 570 40 physiologic physiologic JJ cord-006870-f5w6fw6q 570 41 parameters parameter NNS cord-006870-f5w6fw6q 570 42 associated associate VBN cord-006870-f5w6fw6q 570 43 with with IN cord-006870-f5w6fw6q 570 44 outcome outcome NN cord-006870-f5w6fw6q 570 45 . . . cord-006870-f5w6fw6q 571 1 Subgroup subgroup NN cord-006870-f5w6fw6q 571 2 analyses analysis NNS cord-006870-f5w6fw6q 571 3 were be VBD cord-006870-f5w6fw6q 571 4 performed perform VBN cord-006870-f5w6fw6q 571 5 in in IN cord-006870-f5w6fw6q 571 6 subjects subject NNS cord-006870-f5w6fw6q 571 7 with with IN cord-006870-f5w6fw6q 571 8 intracranial intracranial JJ cord-006870-f5w6fw6q 571 9 monitoring monitoring NN cord-006870-f5w6fw6q 571 10 ( ( -LRB- cord-006870-f5w6fw6q 571 11 tICP ticp XX cord-006870-f5w6fw6q 571 12 , , , cord-006870-f5w6fw6q 571 13 n=480 n=480 NNP cord-006870-f5w6fw6q 571 14 ) ) -RRB- cord-006870-f5w6fw6q 571 15 . . . cord-006870-f5w6fw6q 572 1 Parameters parameter NNS cord-006870-f5w6fw6q 572 2 significant significant JJ cord-006870-f5w6fw6q 572 3 at at IN cord-006870-f5w6fw6q 572 4 alpha alpha NN cord-006870-f5w6fw6q 572 5 0.01 0.01 CD cord-006870-f5w6fw6q 572 6 are be VBP cord-006870-f5w6fw6q 572 7 reported report VBN cord-006870-f5w6fw6q 572 8 . . . cord-006870-f5w6fw6q 573 1 Prolonged prolonged JJ cord-006870-f5w6fw6q 573 2 duration duration NN cord-006870-f5w6fw6q 573 3 of of IN cord-006870-f5w6fw6q 573 4 transgression transgression NN cord-006870-f5w6fw6q 573 5 was be VBD cord-006870-f5w6fw6q 573 6 associated associate VBN cord-006870-f5w6fw6q 573 7 with with IN cord-006870-f5w6fw6q 573 8 poor poor JJ cord-006870-f5w6fw6q 573 9 outcome outcome NN cord-006870-f5w6fw6q 573 10 when when WRB cord-006870-f5w6fw6q 573 11 : : : cord-006870-f5w6fw6q 573 12 glucose>180mg glucose>180mg NNP cord-006870-f5w6fw6q 573 13 / / SYM cord-006870-f5w6fw6q 573 14 dl dl NNP cord-006870-f5w6fw6q 573 15 ( ( -LRB- cord-006870-f5w6fw6q 573 16 p=0.0001 p=0.0001 NNP cord-006870-f5w6fw6q 573 17 ) ) -RRB- cord-006870-f5w6fw6q 573 18 ; ; : cord-006870-f5w6fw6q 573 19 Hgb180mg Hgb180mg NNP cord-006870-f5w6fw6q 573 20 / / SYM cord-006870-f5w6fw6q 573 21 dl dl NN cord-006870-f5w6fw6q 573 22 ( ( -LRB- cord-006870-f5w6fw6q 573 23 p=0.0098 p=0.0098 NNP cord-006870-f5w6fw6q 573 24 ) ) -RRB- cord-006870-f5w6fw6q 573 25 and and CC cord-006870-f5w6fw6q 573 26 inversely inversely RB cord-006870-f5w6fw6q 573 27 associated associate VBN cord-006870-f5w6fw6q 573 28 with with IN cord-006870-f5w6fw6q 573 29 MAP180 MAP180 NNP cord-006870-f5w6fw6q 573 30 mg mg NNP cord-006870-f5w6fw6q 573 31 / / SYM cord-006870-f5w6fw6q 573 32 dL dL NNP cord-006870-f5w6fw6q 573 33 ( ( -LRB- cord-006870-f5w6fw6q 573 34 p=0.0015 p=0.0015 NNP cord-006870-f5w6fw6q 573 35 ) ) -RRB- cord-006870-f5w6fw6q 573 36 or or CC cord-006870-f5w6fw6q 574 1 and and CC cord-006870-f5w6fw6q 574 2 was be VBD cord-006870-f5w6fw6q 574 3 inversely inversely RB cord-006870-f5w6fw6q 574 4 associated associate VBN cord-006870-f5w6fw6q 574 5 with with IN cord-006870-f5w6fw6q 574 6 MAP<65mmHg MAP<65mmHg NNP cord-006870-f5w6fw6q 574 7 ( ( -LRB- cord-006870-f5w6fw6q 574 8 p=0.0055 p=0.0055 NNP cord-006870-f5w6fw6q 574 9 ) ) -RRB- cord-006870-f5w6fw6q 574 10 . . . cord-006870-f5w6fw6q 575 1 The the DT cord-006870-f5w6fw6q 575 2 ProTECT ProTECT NNS cord-006870-f5w6fw6q 575 3 III iii CD cord-006870-f5w6fw6q 575 4 clinical clinical JJ cord-006870-f5w6fw6q 575 5 trial trial NN cord-006870-f5w6fw6q 575 6 rigorously rigorously RB cord-006870-f5w6fw6q 575 7 monitored monitor VBD cord-006870-f5w6fw6q 575 8 compliance compliance NN cord-006870-f5w6fw6q 575 9 with with IN cord-006870-f5w6fw6q 575 10 GDT GDT NNP cord-006870-f5w6fw6q 575 11 after after IN cord-006870-f5w6fw6q 575 12 TBI TBI NNP cord-006870-f5w6fw6q 575 13 . . . cord-006870-f5w6fw6q 576 1 Multiple multiple JJ cord-006870-f5w6fw6q 576 2 significant significant JJ cord-006870-f5w6fw6q 576 3 associations association NNS cord-006870-f5w6fw6q 576 4 between between IN cord-006870-f5w6fw6q 576 5 physiologic physiologic JJ cord-006870-f5w6fw6q 576 6 transgressions transgression NNS cord-006870-f5w6fw6q 576 7 and and CC cord-006870-f5w6fw6q 576 8 patient patient JJ cord-006870-f5w6fw6q 576 9 outcome outcome NN cord-006870-f5w6fw6q 576 10 were be VBD cord-006870-f5w6fw6q 576 11 found find VBN cord-006870-f5w6fw6q 576 12 . . . cord-006870-f5w6fw6q 577 1 The the DT cord-006870-f5w6fw6q 577 2 data datum NNS cord-006870-f5w6fw6q 577 3 suggest suggest VBP cord-006870-f5w6fw6q 577 4 that that IN cord-006870-f5w6fw6q 577 5 reducing reduce VBG cord-006870-f5w6fw6q 577 6 physiologic physiologic JJ cord-006870-f5w6fw6q 577 7 transgressions transgression NNS cord-006870-f5w6fw6q 577 8 is be VBZ cord-006870-f5w6fw6q 577 9 important important JJ cord-006870-f5w6fw6q 577 10 to to IN cord-006870-f5w6fw6q 577 11 minimizing minimize VBG cord-006870-f5w6fw6q 577 12 patient patient JJ cord-006870-f5w6fw6q 577 13 morbidity morbidity NN cord-006870-f5w6fw6q 577 14 after after IN cord-006870-f5w6fw6q 577 15 TBI TBI NNP cord-006870-f5w6fw6q 577 16 . . . cord-006870-f5w6fw6q 578 1 The the DT cord-006870-f5w6fw6q 578 2 measurement measurement NN cord-006870-f5w6fw6q 578 3 and and CC cord-006870-f5w6fw6q 578 4 management management NN cord-006870-f5w6fw6q 578 5 of of IN cord-006870-f5w6fw6q 578 6 intracranial intracranial JJ cord-006870-f5w6fw6q 578 7 pressure pressure NN cord-006870-f5w6fw6q 578 8 ( ( -LRB- cord-006870-f5w6fw6q 578 9 ICP ICP NNP cord-006870-f5w6fw6q 578 10 ) ) -RRB- cord-006870-f5w6fw6q 578 11 is be VBZ cord-006870-f5w6fw6q 578 12 a a DT cord-006870-f5w6fw6q 578 13 key key JJ cord-006870-f5w6fw6q 578 14 component component NN cord-006870-f5w6fw6q 578 15 in in IN cord-006870-f5w6fw6q 578 16 the the DT cord-006870-f5w6fw6q 578 17 care care NN cord-006870-f5w6fw6q 578 18 of of IN cord-006870-f5w6fw6q 578 19 severe severe JJ cord-006870-f5w6fw6q 578 20 head head NN cord-006870-f5w6fw6q 578 21 injury injury NN cord-006870-f5w6fw6q 578 22 . . . cord-006870-f5w6fw6q 579 1 Extracranial extracranial JJ cord-006870-f5w6fw6q 579 2 ventricular ventricular JJ cord-006870-f5w6fw6q 579 3 drains drain NNS cord-006870-f5w6fw6q 579 4 ( ( -LRB- cord-006870-f5w6fw6q 579 5 EVD EVD NNP cord-006870-f5w6fw6q 579 6 ) ) -RRB- cord-006870-f5w6fw6q 579 7 have have VBP cord-006870-f5w6fw6q 579 8 remained remain VBN cord-006870-f5w6fw6q 579 9 the the DT cord-006870-f5w6fw6q 579 10 standard standard NN cord-006870-f5w6fw6q 579 11 due due IN cord-006870-f5w6fw6q 579 12 to to IN cord-006870-f5w6fw6q 579 13 the the DT cord-006870-f5w6fw6q 579 14 ability ability NN cord-006870-f5w6fw6q 579 15 to to TO cord-006870-f5w6fw6q 579 16 lower lower VB cord-006870-f5w6fw6q 579 17 ICP ICP NNP cord-006870-f5w6fw6q 579 18 with with IN cord-006870-f5w6fw6q 579 19 the the DT cord-006870-f5w6fw6q 579 20 drainage drainage NN cord-006870-f5w6fw6q 579 21 of of IN cord-006870-f5w6fw6q 579 22 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 579 23 fluid fluid NN cord-006870-f5w6fw6q 579 24 ( ( -LRB- cord-006870-f5w6fw6q 579 25 CSF CSF NNP cord-006870-f5w6fw6q 579 26 ) ) -RRB- cord-006870-f5w6fw6q 579 27 . . . cord-006870-f5w6fw6q 580 1 Placement placement NN cord-006870-f5w6fw6q 580 2 of of IN cord-006870-f5w6fw6q 580 3 an an DT cord-006870-f5w6fw6q 580 4 EVD EVD NNP cord-006870-f5w6fw6q 580 5 is be VBZ cord-006870-f5w6fw6q 580 6 a a DT cord-006870-f5w6fw6q 580 7 more more RBR cord-006870-f5w6fw6q 580 8 invasive invasive JJ cord-006870-f5w6fw6q 580 9 procedure procedure NN cord-006870-f5w6fw6q 580 10 than than IN cord-006870-f5w6fw6q 580 11 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 580 12 ICP ICP NNP cord-006870-f5w6fw6q 580 13 monitors monitor NNS cord-006870-f5w6fw6q 580 14 ( ( -LRB- cord-006870-f5w6fw6q 580 15 IPM IPM NNP cord-006870-f5w6fw6q 580 16 ) ) -RRB- cord-006870-f5w6fw6q 580 17 and and CC cord-006870-f5w6fw6q 580 18 it -PRON- PRP cord-006870-f5w6fw6q 580 19 is be VBZ cord-006870-f5w6fw6q 580 20 unclear unclear JJ cord-006870-f5w6fw6q 580 21 if if IN cord-006870-f5w6fw6q 580 22 the the DT cord-006870-f5w6fw6q 580 23 use use NN cord-006870-f5w6fw6q 580 24 of of IN cord-006870-f5w6fw6q 580 25 an an DT cord-006870-f5w6fw6q 580 26 EVD EVD NNP cord-006870-f5w6fw6q 580 27 improves improve VBZ cord-006870-f5w6fw6q 580 28 outcomes outcome NNS cord-006870-f5w6fw6q 580 29 . . . cord-006870-f5w6fw6q 581 1 We -PRON- PRP cord-006870-f5w6fw6q 581 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 581 3 that that IN cord-006870-f5w6fw6q 581 4 early early JJ cord-006870-f5w6fw6q 581 5 placement placement NN cord-006870-f5w6fw6q 581 6 of of IN cord-006870-f5w6fw6q 581 7 an an DT cord-006870-f5w6fw6q 581 8 EVD EVD NNP cord-006870-f5w6fw6q 581 9 , , , cord-006870-f5w6fw6q 581 10 in in IN cord-006870-f5w6fw6q 581 11 adult adult NN cord-006870-f5w6fw6q 581 12 patients patient NNS cord-006870-f5w6fw6q 581 13 with with IN cord-006870-f5w6fw6q 581 14 severe severe JJ cord-006870-f5w6fw6q 581 15 head head NN cord-006870-f5w6fw6q 581 16 injury injury NN cord-006870-f5w6fw6q 581 17 , , , cord-006870-f5w6fw6q 581 18 would would MD cord-006870-f5w6fw6q 581 19 not not RB cord-006870-f5w6fw6q 581 20 affect affect VB cord-006870-f5w6fw6q 581 21 outcomes outcome NNS cord-006870-f5w6fw6q 581 22 . . . cord-006870-f5w6fw6q 582 1 Utilizing utilize VBG cord-006870-f5w6fw6q 582 2 data datum NNS cord-006870-f5w6fw6q 582 3 from from IN cord-006870-f5w6fw6q 582 4 the the DT cord-006870-f5w6fw6q 582 5 Citicoline Citicoline NNP cord-006870-f5w6fw6q 582 6 Brain Brain NNP cord-006870-f5w6fw6q 582 7 Injury Injury NNP cord-006870-f5w6fw6q 582 8 Treatment Treatment NNP cord-006870-f5w6fw6q 582 9 ( ( -LRB- cord-006870-f5w6fw6q 582 10 COBRIT cobrit NN cord-006870-f5w6fw6q 582 11 ) ) -RRB- cord-006870-f5w6fw6q 582 12 trial trial NN cord-006870-f5w6fw6q 582 13 , , , cord-006870-f5w6fw6q 582 14 a a DT cord-006870-f5w6fw6q 582 15 prospective prospective JJ cord-006870-f5w6fw6q 582 16 multicenter multicenter JJ cord-006870-f5w6fw6q 582 17 study study NN cord-006870-f5w6fw6q 582 18 , , , cord-006870-f5w6fw6q 582 19 we -PRON- PRP cord-006870-f5w6fw6q 582 20 identified identify VBD cord-006870-f5w6fw6q 582 21 224 224 CD cord-006870-f5w6fw6q 582 22 patients patient NNS cord-006870-f5w6fw6q 582 23 who who WP cord-006870-f5w6fw6q 582 24 met meet VBD cord-006870-f5w6fw6q 582 25 the the DT cord-006870-f5w6fw6q 582 26 inclusion inclusion NN cord-006870-f5w6fw6q 582 27 criteria criterion NNS cord-006870-f5w6fw6q 582 28 ; ; : cord-006870-f5w6fw6q 582 29 1 1 LS cord-006870-f5w6fw6q 582 30 ) ) -RRB- cord-006870-f5w6fw6q 582 31 placement placement NN cord-006870-f5w6fw6q 582 32 of of IN cord-006870-f5w6fw6q 582 33 an an DT cord-006870-f5w6fw6q 582 34 ICP ICP NNP cord-006870-f5w6fw6q 582 35 monitoring monitoring NN cord-006870-f5w6fw6q 582 36 device device NN cord-006870-f5w6fw6q 582 37 , , , cord-006870-f5w6fw6q 582 38 2 2 CD cord-006870-f5w6fw6q 582 39 ) ) -RRB- cord-006870-f5w6fw6q 582 40 Glasgow Glasgow NNP cord-006870-f5w6fw6q 582 41 coma coma NN cord-006870-f5w6fw6q 582 42 score score NN cord-006870-f5w6fw6q 582 43 ( ( -LRB- cord-006870-f5w6fw6q 582 44 GCS GCS NNP cord-006870-f5w6fw6q 582 45 ) ) -RRB- cord-006870-f5w6fw6q 583 1 less less JJR cord-006870-f5w6fw6q 583 2 than than IN cord-006870-f5w6fw6q 583 3 9 9 CD cord-006870-f5w6fw6q 583 4 , , , cord-006870-f5w6fw6q 583 5 3 3 CD cord-006870-f5w6fw6q 583 6 ) ) -RRB- cord-006870-f5w6fw6q 583 7 EVD evd NN cord-006870-f5w6fw6q 583 8 placement placement NN cord-006870-f5w6fw6q 583 9 prior prior RB cord-006870-f5w6fw6q 583 10 to to IN cord-006870-f5w6fw6q 583 11 arrival arrival NN cord-006870-f5w6fw6q 583 12 or or CC cord-006870-f5w6fw6q 583 13 within within IN cord-006870-f5w6fw6q 583 14 6 6 CD cord-006870-f5w6fw6q 583 15 hours hour NNS cord-006870-f5w6fw6q 583 16 of of IN cord-006870-f5w6fw6q 583 17 arrival arrival NN cord-006870-f5w6fw6q 583 18 at at IN cord-006870-f5w6fw6q 583 19 the the DT cord-006870-f5w6fw6q 583 20 study study NN cord-006870-f5w6fw6q 583 21 institution institution NN cord-006870-f5w6fw6q 583 22 . . . cord-006870-f5w6fw6q 584 1 Primary primary JJ cord-006870-f5w6fw6q 584 2 outcome outcome NN cord-006870-f5w6fw6q 584 3 was be VBD cord-006870-f5w6fw6q 584 4 Glasgow Glasgow NNP cord-006870-f5w6fw6q 584 5 outcome outcome NN cord-006870-f5w6fw6q 584 6 score score NN cord-006870-f5w6fw6q 584 7 - - HYPH cord-006870-f5w6fw6q 584 8 extended extend VBN cord-006870-f5w6fw6q 584 9 ( ( -LRB- cord-006870-f5w6fw6q 584 10 GOSE GOSE NNP cord-006870-f5w6fw6q 584 11 ) ) -RRB- cord-006870-f5w6fw6q 584 12 at at IN cord-006870-f5w6fw6q 584 13 180 180 CD cord-006870-f5w6fw6q 584 14 days day NNS cord-006870-f5w6fw6q 584 15 post post NN cord-006870-f5w6fw6q 584 16 injury injury NN cord-006870-f5w6fw6q 584 17 . . . cord-006870-f5w6fw6q 585 1 Secondary secondary JJ cord-006870-f5w6fw6q 585 2 outcomes outcome NNS cord-006870-f5w6fw6q 585 3 included include VBD cord-006870-f5w6fw6q 585 4 neuropsychological neuropsychological JJ cord-006870-f5w6fw6q 585 5 evaluations evaluation NNS cord-006870-f5w6fw6q 585 6 at at IN cord-006870-f5w6fw6q 585 7 180 180 CD cord-006870-f5w6fw6q 585 8 days day NNS cord-006870-f5w6fw6q 585 9 post post NN cord-006870-f5w6fw6q 585 10 injury injury NN cord-006870-f5w6fw6q 585 11 , , , cord-006870-f5w6fw6q 585 12 mortality mortality NN cord-006870-f5w6fw6q 585 13 , , , cord-006870-f5w6fw6q 585 14 and and CC cord-006870-f5w6fw6q 585 15 length length NN cord-006870-f5w6fw6q 585 16 of of IN cord-006870-f5w6fw6q 585 17 ICU ICU NNP cord-006870-f5w6fw6q 585 18 stay stay NN cord-006870-f5w6fw6q 585 19 . . . cord-006870-f5w6fw6q 586 1 Logistic logistic JJ cord-006870-f5w6fw6q 586 2 regression regression NN cord-006870-f5w6fw6q 586 3 with with IN cord-006870-f5w6fw6q 586 4 forward forward RB cord-006870-f5w6fw6q 586 5 - - HYPH cord-006870-f5w6fw6q 586 6 stepwise stepwise JJ cord-006870-f5w6fw6q 586 7 predictor predictor NN cord-006870-f5w6fw6q 586 8 adjustment adjustment NN cord-006870-f5w6fw6q 586 9 and and CC cord-006870-f5w6fw6q 586 10 propensity propensity NN cord-006870-f5w6fw6q 586 11 score score NN cord-006870-f5w6fw6q 586 12 adjustment adjustment NN cord-006870-f5w6fw6q 586 13 was be VBD cord-006870-f5w6fw6q 586 14 performed perform VBN cord-006870-f5w6fw6q 586 15 to to TO cord-006870-f5w6fw6q 586 16 assess assess VB cord-006870-f5w6fw6q 586 17 the the DT cord-006870-f5w6fw6q 586 18 independent independent JJ cord-006870-f5w6fw6q 586 19 association association NN cord-006870-f5w6fw6q 586 20 between between IN cord-006870-f5w6fw6q 586 21 EVD EVD NNP cord-006870-f5w6fw6q 586 22 placement placement NN cord-006870-f5w6fw6q 586 23 and and CC cord-006870-f5w6fw6q 586 24 outcomes outcome NNS cord-006870-f5w6fw6q 586 25 . . . cord-006870-f5w6fw6q 587 1 Patients patient NNS cord-006870-f5w6fw6q 587 2 who who WP cord-006870-f5w6fw6q 587 3 received receive VBD cord-006870-f5w6fw6q 587 4 an an DT cord-006870-f5w6fw6q 587 5 EVD EVD NNP cord-006870-f5w6fw6q 587 6 prior prior RB cord-006870-f5w6fw6q 587 7 to to IN cord-006870-f5w6fw6q 587 8 or or CC cord-006870-f5w6fw6q 587 9 within within IN cord-006870-f5w6fw6q 587 10 6 6 CD cord-006870-f5w6fw6q 587 11 hours hour NNS cord-006870-f5w6fw6q 587 12 of of IN cord-006870-f5w6fw6q 587 13 arrival arrival NN cord-006870-f5w6fw6q 587 14 at at IN cord-006870-f5w6fw6q 587 15 the the DT cord-006870-f5w6fw6q 587 16 study study NN cord-006870-f5w6fw6q 587 17 institution institution NN cord-006870-f5w6fw6q 587 18 had have VBD cord-006870-f5w6fw6q 587 19 worse bad JJR cord-006870-f5w6fw6q 587 20 GOSE GOSE NNP cord-006870-f5w6fw6q 587 21 at at IN cord-006870-f5w6fw6q 587 22 180 180 CD cord-006870-f5w6fw6q 587 23 days day NNS cord-006870-f5w6fw6q 587 24 ( ( -LRB- cord-006870-f5w6fw6q 587 25 3.8 3.8 CD cord-006870-f5w6fw6q 587 26 ± ± CD cord-006870-f5w6fw6q 587 27 2.2 2.2 CD cord-006870-f5w6fw6q 587 28 vs vs IN cord-006870-f5w6fw6q 587 29 4.9 4.9 CD cord-006870-f5w6fw6q 587 30 ± ± CD cord-006870-f5w6fw6q 587 31 2.2 2.2 CD cord-006870-f5w6fw6q 587 32 , , , cord-006870-f5w6fw6q 587 33 p=0.007 p=0.007 NNP cord-006870-f5w6fw6q 587 34 ) ) -RRB- cord-006870-f5w6fw6q 587 35 , , , cord-006870-f5w6fw6q 587 36 higher high JJR cord-006870-f5w6fw6q 587 37 in in IN cord-006870-f5w6fw6q 587 38 hospital hospital NN cord-006870-f5w6fw6q 587 39 mortality mortality NN cord-006870-f5w6fw6q 587 40 ( ( -LRB- cord-006870-f5w6fw6q 587 41 23 23 CD cord-006870-f5w6fw6q 587 42 % % NN cord-006870-f5w6fw6q 587 43 vs vs IN cord-006870-f5w6fw6q 587 44 10 10 CD cord-006870-f5w6fw6q 587 45 % % NN cord-006870-f5w6fw6q 587 46 , , , cord-006870-f5w6fw6q 587 47 p p NN cord-006870-f5w6fw6q 587 48 = = SYM cord-006870-f5w6fw6q 587 49 0.021 0.021 CD cord-006870-f5w6fw6q 587 50 ) ) -RRB- cord-006870-f5w6fw6q 587 51 , , , cord-006870-f5w6fw6q 587 52 and and CC cord-006870-f5w6fw6q 587 53 did do VBD cord-006870-f5w6fw6q 587 54 worse bad JJR cord-006870-f5w6fw6q 587 55 on on IN cord-006870-f5w6fw6q 587 56 4 4 CD cord-006870-f5w6fw6q 587 57 out out IN cord-006870-f5w6fw6q 587 58 of of IN cord-006870-f5w6fw6q 587 59 8 8 CD cord-006870-f5w6fw6q 587 60 neuropsychological neuropsychological JJ cord-006870-f5w6fw6q 587 61 measures measure NNS cord-006870-f5w6fw6q 587 62 at at IN cord-006870-f5w6fw6q 587 63 180 180 CD cord-006870-f5w6fw6q 587 64 days day NNS cord-006870-f5w6fw6q 587 65 . . . cord-006870-f5w6fw6q 588 1 There there EX cord-006870-f5w6fw6q 588 2 was be VBD cord-006870-f5w6fw6q 588 3 no no DT cord-006870-f5w6fw6q 588 4 difference difference NN cord-006870-f5w6fw6q 588 5 in in IN cord-006870-f5w6fw6q 588 6 ICU ICU NNP cord-006870-f5w6fw6q 588 7 length length NN cord-006870-f5w6fw6q 588 8 of of IN cord-006870-f5w6fw6q 588 9 stay stay NN cord-006870-f5w6fw6q 588 10 ( ( -LRB- cord-006870-f5w6fw6q 588 11 16.5 16.5 CD cord-006870-f5w6fw6q 588 12 ± ± NNP cord-006870-f5w6fw6q 588 13 9.0 9.0 CD cord-006870-f5w6fw6q 588 14 vs vs IN cord-006870-f5w6fw6q 588 15 13.9 13.9 CD cord-006870-f5w6fw6q 588 16 ± ± CD cord-006870-f5w6fw6q 588 17 10.8 10.8 CD cord-006870-f5w6fw6q 588 18 , , , cord-006870-f5w6fw6q 588 19 p=0.289 p=0.289 NN cord-006870-f5w6fw6q 588 20 ) ) -RRB- cord-006870-f5w6fw6q 588 21 . . . cord-006870-f5w6fw6q 589 1 Early early JJ cord-006870-f5w6fw6q 589 2 placement placement NN cord-006870-f5w6fw6q 589 3 of of IN cord-006870-f5w6fw6q 589 4 EVDs evds NN cord-006870-f5w6fw6q 589 5 in in IN cord-006870-f5w6fw6q 589 6 severe severe JJ cord-006870-f5w6fw6q 589 7 adult adult NN cord-006870-f5w6fw6q 589 8 head head NN cord-006870-f5w6fw6q 589 9 injury injury NN cord-006870-f5w6fw6q 589 10 is be VBZ cord-006870-f5w6fw6q 589 11 independently independently RB cord-006870-f5w6fw6q 589 12 associated associate VBN cord-006870-f5w6fw6q 589 13 with with IN cord-006870-f5w6fw6q 589 14 worse bad JJR cord-006870-f5w6fw6q 589 15 outcomes outcome NNS cord-006870-f5w6fw6q 589 16 and and CC cord-006870-f5w6fw6q 589 17 higher high JJR cord-006870-f5w6fw6q 589 18 in in IN cord-006870-f5w6fw6q 589 19 hospital hospital NN cord-006870-f5w6fw6q 589 20 mortality mortality NN cord-006870-f5w6fw6q 589 21 . . . cord-006870-f5w6fw6q 590 1 Goal Goal NNP cord-006870-f5w6fw6q 590 2 Directed Directed NNP cord-006870-f5w6fw6q 590 3 Therapy Therapy NNP cord-006870-f5w6fw6q 590 4 ( ( -LRB- cord-006870-f5w6fw6q 590 5 GDT GDT NNP cord-006870-f5w6fw6q 590 6 ) ) -RRB- cord-006870-f5w6fw6q 590 7 is be VBZ cord-006870-f5w6fw6q 590 8 thought think VBN cord-006870-f5w6fw6q 590 9 to to TO cord-006870-f5w6fw6q 590 10 be be VB cord-006870-f5w6fw6q 590 11 associated associate VBN cord-006870-f5w6fw6q 590 12 with with IN cord-006870-f5w6fw6q 590 13 outcome outcome NN cord-006870-f5w6fw6q 590 14 after after IN cord-006870-f5w6fw6q 590 15 traumatic traumatic JJ cord-006870-f5w6fw6q 590 16 brain brain NN cord-006870-f5w6fw6q 590 17 injury injury NN cord-006870-f5w6fw6q 590 18 ( ( -LRB- cord-006870-f5w6fw6q 590 19 TBI TBI NNP cord-006870-f5w6fw6q 590 20 ) ) -RRB- cord-006870-f5w6fw6q 590 21 . . . cord-006870-f5w6fw6q 591 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 591 2 team team NN cord-006870-f5w6fw6q 591 3 applied apply VBD cord-006870-f5w6fw6q 591 4 GDT GDT NNP cord-006870-f5w6fw6q 591 5 to to TO cord-006870-f5w6fw6q 591 6 standardize standardize VB cord-006870-f5w6fw6q 591 7 care care NN cord-006870-f5w6fw6q 591 8 in in IN cord-006870-f5w6fw6q 591 9 patients patient NNS cord-006870-f5w6fw6q 591 10 with with IN cord-006870-f5w6fw6q 591 11 moderate moderate JJ cord-006870-f5w6fw6q 591 12 to to IN cord-006870-f5w6fw6q 591 13 severe severe JJ cord-006870-f5w6fw6q 591 14 TBI TBI NNP cord-006870-f5w6fw6q 591 15 , , , cord-006870-f5w6fw6q 591 16 who who WP cord-006870-f5w6fw6q 591 17 were be VBD cord-006870-f5w6fw6q 591 18 enrolled enrol VBN cord-006870-f5w6fw6q 591 19 in in IN cord-006870-f5w6fw6q 591 20 a a DT cord-006870-f5w6fw6q 591 21 large large JJ cord-006870-f5w6fw6q 591 22 multicenter multicenter JJ cord-006870-f5w6fw6q 591 23 clinical clinical JJ cord-006870-f5w6fw6q 591 24 trial trial NN cord-006870-f5w6fw6q 591 25 . . . cord-006870-f5w6fw6q 592 1 Physiologic physiologic JJ cord-006870-f5w6fw6q 592 2 goals goal NNS cord-006870-f5w6fw6q 592 3 were be VBD cord-006870-f5w6fw6q 592 4 defined define VBN cord-006870-f5w6fw6q 592 5 a a DT cord-006870-f5w6fw6q 592 6 priori priori FW cord-006870-f5w6fw6q 592 7 in in IN cord-006870-f5w6fw6q 592 8 order order NN cord-006870-f5w6fw6q 592 9 to to TO cord-006870-f5w6fw6q 592 10 standardize standardize VB cord-006870-f5w6fw6q 592 11 care care NN cord-006870-f5w6fw6q 592 12 across across IN cord-006870-f5w6fw6q 592 13 42 42 CD cord-006870-f5w6fw6q 592 14 sites site NNS cord-006870-f5w6fw6q 592 15 participating participate VBG cord-006870-f5w6fw6q 592 16 in in IN cord-006870-f5w6fw6q 592 17 the the DT cord-006870-f5w6fw6q 592 18 ProTECT ProTECT NNS cord-006870-f5w6fw6q 592 19 III iii CD cord-006870-f5w6fw6q 592 20 trial trial NN cord-006870-f5w6fw6q 592 21 . . . cord-006870-f5w6fw6q 593 1 Data datum NNS cord-006870-f5w6fw6q 593 2 were be VBD cord-006870-f5w6fw6q 593 3 collected collect VBN cord-006870-f5w6fw6q 593 4 hourly hourly RB cord-006870-f5w6fw6q 593 5 for for IN cord-006870-f5w6fw6q 593 6 all all DT cord-006870-f5w6fw6q 593 7 randomized randomized JJ cord-006870-f5w6fw6q 593 8 subjects subject NNS cord-006870-f5w6fw6q 593 9 ( ( -LRB- cord-006870-f5w6fw6q 593 10 n=882 n=882 NNP cord-006870-f5w6fw6q 593 11 ) ) -RRB- cord-006870-f5w6fw6q 593 12 . . . cord-006870-f5w6fw6q 594 1 Hours hour NNS cord-006870-f5w6fw6q 594 2 where where WRB cord-006870-f5w6fw6q 594 3 GDT GDT NNP cord-006870-f5w6fw6q 594 4 were be VBD cord-006870-f5w6fw6q 594 5 not not RB cord-006870-f5w6fw6q 594 6 achieved achieve VBN cord-006870-f5w6fw6q 594 7 were be VBD cord-006870-f5w6fw6q 594 8 classified classify VBN cord-006870-f5w6fw6q 594 9 as as IN cord-006870-f5w6fw6q 594 10 " " `` cord-006870-f5w6fw6q 594 11 transgressions transgression NNS cord-006870-f5w6fw6q 594 12 " " '' cord-006870-f5w6fw6q 594 13 . . . cord-006870-f5w6fw6q 595 1 These these DT cord-006870-f5w6fw6q 595 2 included include VBD cord-006870-f5w6fw6q 595 3 : : : cord-006870-f5w6fw6q 596 1 MAP1.4 MAP1.4 NNP cord-006870-f5w6fw6q 596 2 ; ; : cord-006870-f5w6fw6q 596 3 Platelets180mg Platelets180mg NNP cord-006870-f5w6fw6q 596 4 / / SYM cord-006870-f5w6fw6q 596 5 dl dl NN cord-006870-f5w6fw6q 596 6 ; ; : cord-006870-f5w6fw6q 596 7 and and CC cord-006870-f5w6fw6q 596 8 SBP180mmHg SBP180mmHg NNP cord-006870-f5w6fw6q 596 9 . . . cord-006870-f5w6fw6q 597 1 The the DT cord-006870-f5w6fw6q 597 2 proportion proportion NN cord-006870-f5w6fw6q 597 3 of of IN cord-006870-f5w6fw6q 597 4 hours hour NNS cord-006870-f5w6fw6q 597 5 spent spend VBN cord-006870-f5w6fw6q 597 6 in in IN cord-006870-f5w6fw6q 597 7 transgression transgression NN cord-006870-f5w6fw6q 597 8 was be VBD cord-006870-f5w6fw6q 597 9 calculated calculate VBN cord-006870-f5w6fw6q 597 10 for for IN cord-006870-f5w6fw6q 597 11 each each DT cord-006870-f5w6fw6q 597 12 parameter parameter NN cord-006870-f5w6fw6q 597 13 and and CC cord-006870-f5w6fw6q 597 14 grouped group VBN cord-006870-f5w6fw6q 597 15 by by IN cord-006870-f5w6fw6q 597 16 quartile quartile NN cord-006870-f5w6fw6q 597 17 . . . cord-006870-f5w6fw6q 598 1 Data datum NNS cord-006870-f5w6fw6q 598 2 were be VBD cord-006870-f5w6fw6q 598 3 adjudicated adjudicate VBN cord-006870-f5w6fw6q 598 4 electronically electronically RB cord-006870-f5w6fw6q 598 5 and and CC cord-006870-f5w6fw6q 598 6 via via IN cord-006870-f5w6fw6q 598 7 expert expert NN cord-006870-f5w6fw6q 598 8 review review NN cord-006870-f5w6fw6q 598 9 . . . cord-006870-f5w6fw6q 599 1 For for IN cord-006870-f5w6fw6q 599 2 each each DT cord-006870-f5w6fw6q 599 3 parameter parameter NN cord-006870-f5w6fw6q 599 4 , , , cord-006870-f5w6fw6q 599 5 the the DT cord-006870-f5w6fw6q 599 6 association association NN cord-006870-f5w6fw6q 599 7 between between IN cord-006870-f5w6fw6q 599 8 outcome outcome NN cord-006870-f5w6fw6q 599 9 and and CC cord-006870-f5w6fw6q 599 10 either either RB cord-006870-f5w6fw6q 599 11 ( ( -LRB- cord-006870-f5w6fw6q 599 12 1 1 LS cord-006870-f5w6fw6q 599 13 ) ) -RRB- cord-006870-f5w6fw6q 599 14 occurrence occurrence NN cord-006870-f5w6fw6q 599 15 of of IN cord-006870-f5w6fw6q 599 16 transgression transgression NN cord-006870-f5w6fw6q 599 17 or or CC cord-006870-f5w6fw6q 599 18 ( ( -LRB- cord-006870-f5w6fw6q 599 19 2 2 LS cord-006870-f5w6fw6q 599 20 ) ) -RRB- cord-006870-f5w6fw6q 599 21 cumulative cumulative JJ cord-006870-f5w6fw6q 599 22 duration duration NN cord-006870-f5w6fw6q 599 23 of of IN cord-006870-f5w6fw6q 599 24 transgression transgression NN cord-006870-f5w6fw6q 599 25 was be VBD cord-006870-f5w6fw6q 599 26 estimated estimate VBN cord-006870-f5w6fw6q 599 27 via via IN cord-006870-f5w6fw6q 599 28 logistic logistic JJ cord-006870-f5w6fw6q 599 29 regression regression NN cord-006870-f5w6fw6q 599 30 model model NN cord-006870-f5w6fw6q 599 31 , , , cord-006870-f5w6fw6q 599 32 and and CC cord-006870-f5w6fw6q 599 33 backward backward JJ cord-006870-f5w6fw6q 599 34 selection selection NN cord-006870-f5w6fw6q 599 35 was be VBD cord-006870-f5w6fw6q 599 36 used use VBN cord-006870-f5w6fw6q 599 37 to to TO cord-006870-f5w6fw6q 599 38 identify identify VB cord-006870-f5w6fw6q 599 39 the the DT cord-006870-f5w6fw6q 599 40 physiologic physiologic JJ cord-006870-f5w6fw6q 599 41 parameters parameter NNS cord-006870-f5w6fw6q 599 42 associated associate VBN cord-006870-f5w6fw6q 599 43 with with IN cord-006870-f5w6fw6q 599 44 mortality mortality NN cord-006870-f5w6fw6q 599 45 . . . cord-006870-f5w6fw6q 600 1 Subgroup subgroup NN cord-006870-f5w6fw6q 600 2 analyses analysis NNS cord-006870-f5w6fw6q 600 3 were be VBD cord-006870-f5w6fw6q 600 4 performed perform VBN cord-006870-f5w6fw6q 600 5 in in IN cord-006870-f5w6fw6q 600 6 subjects subject NNS cord-006870-f5w6fw6q 600 7 with with IN cord-006870-f5w6fw6q 600 8 intracranial intracranial JJ cord-006870-f5w6fw6q 600 9 monitoring monitoring NN cord-006870-f5w6fw6q 600 10 ( ( -LRB- cord-006870-f5w6fw6q 600 11 tICP ticp XX cord-006870-f5w6fw6q 600 12 , , , cord-006870-f5w6fw6q 600 13 n=480 n=480 NNP cord-006870-f5w6fw6q 600 14 ) ) -RRB- cord-006870-f5w6fw6q 600 15 . . . cord-006870-f5w6fw6q 601 1 Parameters parameter NNS cord-006870-f5w6fw6q 601 2 significant significant JJ cord-006870-f5w6fw6q 601 3 at at IN cord-006870-f5w6fw6q 601 4 alpha alpha NN cord-006870-f5w6fw6q 601 5 0.01 0.01 CD cord-006870-f5w6fw6q 601 6 are be VBP cord-006870-f5w6fw6q 601 7 reported report VBN cord-006870-f5w6fw6q 601 8 . . . cord-006870-f5w6fw6q 602 1 Mortality mortality NN cord-006870-f5w6fw6q 602 2 was be VBD cord-006870-f5w6fw6q 602 3 17.2 17.2 CD cord-006870-f5w6fw6q 602 4 % % NN cord-006870-f5w6fw6q 602 5 and and CC cord-006870-f5w6fw6q 602 6 23.2 23.2 CD cord-006870-f5w6fw6q 602 7 % % NN cord-006870-f5w6fw6q 602 8 in in IN cord-006870-f5w6fw6q 602 9 the the DT cord-006870-f5w6fw6q 602 10 full full JJ cord-006870-f5w6fw6q 602 11 and and CC cord-006870-f5w6fw6q 602 12 tICP ticp JJ cord-006870-f5w6fw6q 602 13 cohorts cohort NNS cord-006870-f5w6fw6q 602 14 . . . cord-006870-f5w6fw6q 603 1 Prolonged prolonged JJ cord-006870-f5w6fw6q 603 2 duration duration NN cord-006870-f5w6fw6q 603 3 of of IN cord-006870-f5w6fw6q 603 4 transgression transgression NN cord-006870-f5w6fw6q 603 5 was be VBD cord-006870-f5w6fw6q 603 6 associated associate VBN cord-006870-f5w6fw6q 603 7 with with IN cord-006870-f5w6fw6q 603 8 increased increase VBN cord-006870-f5w6fw6q 603 9 mortality mortality NN cord-006870-f5w6fw6q 603 10 for for IN cord-006870-f5w6fw6q 603 11 : : : cord-006870-f5w6fw6q 604 1 Hgb1.4 Hgb1.4 NNP cord-006870-f5w6fw6q 604 2 ( ( -LRB- cord-006870-f5w6fw6q 604 3 p180mg p180mg NNP cord-006870-f5w6fw6q 604 4 / / SYM cord-006870-f5w6fw6q 604 5 dl dl NNP cord-006870-f5w6fw6q 604 6 ( ( -LRB- cord-006870-f5w6fw6q 604 7 p180mg p180mg NNP cord-006870-f5w6fw6q 604 8 / / SYM cord-006870-f5w6fw6q 604 9 dl dl NNP cord-006870-f5w6fw6q 604 10 ( ( -LRB- cord-006870-f5w6fw6q 604 11 p=0.0093 p=0.0093 NNP cord-006870-f5w6fw6q 604 12 ) ) -RRB- cord-006870-f5w6fw6q 604 13 , , , cord-006870-f5w6fw6q 604 14 and and CC cord-006870-f5w6fw6q 605 1 SBP1.4 SBP1.4 NNP cord-006870-f5w6fw6q 605 2 ( ( -LRB- cord-006870-f5w6fw6q 605 3 p1.4 p1.4 JJ cord-006870-f5w6fw6q 605 4 ( ( -LRB- cord-006870-f5w6fw6q 605 5 p=0.0005 p=0.0005 NNP cord-006870-f5w6fw6q 605 6 ) ) -RRB- cord-006870-f5w6fw6q 605 7 . . . cord-006870-f5w6fw6q 606 1 Covariates Covariates NNP cord-006870-f5w6fw6q 606 2 inversely inversely RB cord-006870-f5w6fw6q 606 3 related relate VBN cord-006870-f5w6fw6q 606 4 to to IN cord-006870-f5w6fw6q 606 5 mortality mortality NN cord-006870-f5w6fw6q 606 6 included include VBD cord-006870-f5w6fw6q 606 7 single single JJ cord-006870-f5w6fw6q 606 8 occurrence occurrence NN cord-006870-f5w6fw6q 606 9 of of IN cord-006870-f5w6fw6q 606 10 MAP180mmHg MAP180mmHg NNP cord-006870-f5w6fw6q 606 11 ( ( -LRB- cord-006870-f5w6fw6q 606 12 p<0.0032 p<0.0032 NNP cord-006870-f5w6fw6q 606 13 ) ) -RRB- cord-006870-f5w6fw6q 606 14 . . . cord-006870-f5w6fw6q 607 1 The the DT cord-006870-f5w6fw6q 607 2 ProTECT ProTECT NNS cord-006870-f5w6fw6q 607 3 III iii CD cord-006870-f5w6fw6q 607 4 clinical clinical JJ cord-006870-f5w6fw6q 607 5 trial trial NN cord-006870-f5w6fw6q 607 6 rigorously rigorously RB cord-006870-f5w6fw6q 607 7 monitored monitor VBD cord-006870-f5w6fw6q 607 8 compliance compliance NN cord-006870-f5w6fw6q 607 9 with with IN cord-006870-f5w6fw6q 607 10 GDT GDT NNP cord-006870-f5w6fw6q 607 11 after after IN cord-006870-f5w6fw6q 607 12 TBI TBI NNP cord-006870-f5w6fw6q 607 13 . . . cord-006870-f5w6fw6q 608 1 Multiple multiple JJ cord-006870-f5w6fw6q 608 2 associations association NNS cord-006870-f5w6fw6q 608 3 between between IN cord-006870-f5w6fw6q 608 4 physiologic physiologic JJ cord-006870-f5w6fw6q 608 5 transgressions transgression NNS cord-006870-f5w6fw6q 608 6 and and CC cord-006870-f5w6fw6q 608 7 mortality mortality NN cord-006870-f5w6fw6q 608 8 were be VBD cord-006870-f5w6fw6q 608 9 observed observe VBN cord-006870-f5w6fw6q 608 10 . . . cord-006870-f5w6fw6q 609 1 The the DT cord-006870-f5w6fw6q 609 2 data datum NNS cord-006870-f5w6fw6q 609 3 suggest suggest VBP cord-006870-f5w6fw6q 609 4 that that IN cord-006870-f5w6fw6q 609 5 maintaining maintain VBG cord-006870-f5w6fw6q 609 6 physiologic physiologic JJ cord-006870-f5w6fw6q 609 7 measures measure NNS cord-006870-f5w6fw6q 609 8 within within IN cord-006870-f5w6fw6q 609 9 GDT GDT NNP cord-006870-f5w6fw6q 609 10 guidelines guideline NNS cord-006870-f5w6fw6q 609 11 may may MD cord-006870-f5w6fw6q 609 12 be be VB cord-006870-f5w6fw6q 609 13 important important JJ cord-006870-f5w6fw6q 609 14 in in IN cord-006870-f5w6fw6q 609 15 preventing prevent VBG cord-006870-f5w6fw6q 609 16 deaths death NNS cord-006870-f5w6fw6q 609 17 . . . cord-006870-f5w6fw6q 610 1 Current current JJ cord-006870-f5w6fw6q 610 2 outcome outcome NN cord-006870-f5w6fw6q 610 3 models model NNS cord-006870-f5w6fw6q 610 4 in in IN cord-006870-f5w6fw6q 610 5 moderate moderate JJ cord-006870-f5w6fw6q 610 6 - - HYPH cord-006870-f5w6fw6q 610 7 severe severe JJ cord-006870-f5w6fw6q 610 8 traumatic traumatic JJ cord-006870-f5w6fw6q 610 9 brain brain NN cord-006870-f5w6fw6q 610 10 injury injury NN cord-006870-f5w6fw6q 610 11 ( ( -LRB- cord-006870-f5w6fw6q 610 12 msTBI mstbi NN cord-006870-f5w6fw6q 610 13 ) ) -RRB- cord-006870-f5w6fw6q 610 14 include include VBP cord-006870-f5w6fw6q 610 15 only only RB cord-006870-f5w6fw6q 610 16 admission admission NN cord-006870-f5w6fw6q 610 17 characteristics characteristic NNS cord-006870-f5w6fw6q 610 18 . . . cord-006870-f5w6fw6q 611 1 Yet yet RB cord-006870-f5w6fw6q 611 2 , , , cord-006870-f5w6fw6q 611 3 msTBI mstbi NN cord-006870-f5w6fw6q 611 4 patients patient NNS cord-006870-f5w6fw6q 611 5 commonly commonly RB cord-006870-f5w6fw6q 611 6 have have VBP cord-006870-f5w6fw6q 611 7 prolonged prolong VBN cord-006870-f5w6fw6q 611 8 intensive intensive JJ cord-006870-f5w6fw6q 611 9 - - HYPH cord-006870-f5w6fw6q 611 10 care care NN cord-006870-f5w6fw6q 611 11 - - HYPH cord-006870-f5w6fw6q 611 12 unit(ICU)-stays unit(ICU)-stays NNP cord-006870-f5w6fw6q 611 13 with with IN cord-006870-f5w6fw6q 611 14 high high JJ cord-006870-f5w6fw6q 611 15 risks risk NNS cord-006870-f5w6fw6q 611 16 to to TO cord-006870-f5w6fw6q 611 17 develop develop VB cord-006870-f5w6fw6q 611 18 ICU ICU NNP cord-006870-f5w6fw6q 611 19 complications complication NNS cord-006870-f5w6fw6q 611 20 , , , cord-006870-f5w6fw6q 611 21 lending lend VBG cord-006870-f5w6fw6q 611 22 to to IN cord-006870-f5w6fw6q 611 23 the the DT cord-006870-f5w6fw6q 611 24 hypothesis hypothesis NN cord-006870-f5w6fw6q 611 25 that that IN cord-006870-f5w6fw6q 611 26 these these DT cord-006870-f5w6fw6q 611 27 may may MD cord-006870-f5w6fw6q 611 28 be be VB cord-006870-f5w6fw6q 611 29 additionally additionally RB cord-006870-f5w6fw6q 611 30 associated associate VBN cord-006870-f5w6fw6q 611 31 with with IN cord-006870-f5w6fw6q 611 32 outcomes outcome NNS cord-006870-f5w6fw6q 611 33 . . . cord-006870-f5w6fw6q 612 1 The the DT cord-006870-f5w6fw6q 612 2 objective objective NN cord-006870-f5w6fw6q 612 3 of of IN cord-006870-f5w6fw6q 612 4 this this DT cord-006870-f5w6fw6q 612 5 study study NN cord-006870-f5w6fw6q 612 6 was be VBD cord-006870-f5w6fw6q 612 7 to to TO cord-006870-f5w6fw6q 612 8 examine examine VB cord-006870-f5w6fw6q 612 9 the the DT cord-006870-f5w6fw6q 612 10 incidence incidence NN cord-006870-f5w6fw6q 612 11 rates rate NNS cord-006870-f5w6fw6q 612 12 of of IN cord-006870-f5w6fw6q 612 13 pre pre JJ cord-006870-f5w6fw6q 612 14 - - JJ cord-006870-f5w6fw6q 612 15 specified specified JJ cord-006870-f5w6fw6q 612 16 medical medical JJ cord-006870-f5w6fw6q 612 17 and and CC cord-006870-f5w6fw6q 612 18 neurological neurological JJ cord-006870-f5w6fw6q 612 19 ICU ICU NNP cord-006870-f5w6fw6q 612 20 complications complication NNS cord-006870-f5w6fw6q 612 21 , , , cord-006870-f5w6fw6q 612 22 and and CC cord-006870-f5w6fw6q 612 23 their -PRON- PRP$ cord-006870-f5w6fw6q 612 24 impact impact NN cord-006870-f5w6fw6q 612 25 on on IN cord-006870-f5w6fw6q 612 26 post post JJ cord-006870-f5w6fw6q 612 27 - - JJ cord-006870-f5w6fw6q 612 28 traumatic traumatic JJ cord-006870-f5w6fw6q 612 29 in in IN cord-006870-f5w6fw6q 612 30 - - HYPH cord-006870-f5w6fw6q 612 31 hospital hospital NN cord-006870-f5w6fw6q 612 32 mortality mortality NN cord-006870-f5w6fw6q 612 33 and and CC cord-006870-f5w6fw6q 612 34 12month 12month JJ cord-006870-f5w6fw6q 612 35 functional functional JJ cord-006870-f5w6fw6q 612 36 outcomes outcome NNS cord-006870-f5w6fw6q 612 37 . . . cord-006870-f5w6fw6q 613 1 We -PRON- PRP cord-006870-f5w6fw6q 613 2 analyzed analyze VBD cord-006870-f5w6fw6q 613 3 431 431 CD cord-006870-f5w6fw6q 613 4 msTBI mstbi CD cord-006870-f5w6fw6q 613 5 patients patient NNS cord-006870-f5w6fw6q 613 6 consecutively consecutively RB cord-006870-f5w6fw6q 613 7 enrolled enrol VBD cord-006870-f5w6fw6q 613 8 in in IN cord-006870-f5w6fw6q 613 9 the the DT cord-006870-f5w6fw6q 613 10 prospective prospective JJ cord-006870-f5w6fw6q 613 11 observational observational JJ cord-006870-f5w6fw6q 613 12 OPTIMISMstudy optimismstudy NN cord-006870-f5w6fw6q 613 13 at at IN cord-006870-f5w6fw6q 613 14 a a DT cord-006870-f5w6fw6q 613 15 level-1 level-1 NNP cord-006870-f5w6fw6q 613 16 trauma trauma NN cord-006870-f5w6fw6q 613 17 center center NN cord-006870-f5w6fw6q 613 18 between between IN cord-006870-f5w6fw6q 613 19 11/2009 11/2009 CD cord-006870-f5w6fw6q 613 20 - - HYPH cord-006870-f5w6fw6q 613 21 1/2017 1/2017 CD cord-006870-f5w6fw6q 613 22 . . . cord-006870-f5w6fw6q 614 1 Poor poor JJ cord-006870-f5w6fw6q 614 2 outcome outcome NN cord-006870-f5w6fw6q 614 3 was be VBD cord-006870-f5w6fw6q 614 4 defined define VBN cord-006870-f5w6fw6q 614 5 as as IN cord-006870-f5w6fw6q 614 6 Glasgow Glasgow NNP cord-006870-f5w6fw6q 614 7 Outcome Outcome NNP cord-006870-f5w6fw6q 614 8 Scale Scale NNP cord-006870-f5w6fw6q 614 9 1 1 CD cord-006870-f5w6fw6q 614 10 - - SYM cord-006870-f5w6fw6q 614 11 3 3 CD cord-006870-f5w6fw6q 614 12 . . . cord-006870-f5w6fw6q 615 1 Multivariable multivariable JJ cord-006870-f5w6fw6q 615 2 logistic logistic JJ cord-006870-f5w6fw6q 615 3 regression regression NN cord-006870-f5w6fw6q 615 4 was be VBD cord-006870-f5w6fw6q 615 5 employed employ VBN cord-006870-f5w6fw6q 615 6 to to TO cord-006870-f5w6fw6q 615 7 adjust adjust VB cord-006870-f5w6fw6q 615 8 for for IN cord-006870-f5w6fw6q 615 9 admission admission NN cord-006870-f5w6fw6q 615 10 characteristics characteristic NNS cord-006870-f5w6fw6q 615 11 and and CC cord-006870-f5w6fw6q 615 12 ICU ICU NNP cord-006870-f5w6fw6q 615 13 - - HYPH cord-006870-f5w6fw6q 615 14 length length NN cord-006870-f5w6fw6q 615 15 - - HYPH cord-006870-f5w6fw6q 615 16 of of IN cord-006870-f5w6fw6q 615 17 - - HYPH cord-006870-f5w6fw6q 615 18 stay stay NN cord-006870-f5w6fw6q 615 19 . . . cord-006870-f5w6fw6q 616 1 The the DT cord-006870-f5w6fw6q 616 2 mean mean JJ cord-006870-f5w6fw6q 616 3 age age NN cord-006870-f5w6fw6q 616 4 was be VBD cord-006870-f5w6fw6q 616 5 52±22 52±22 NNP cord-006870-f5w6fw6q 616 6 years year NNS cord-006870-f5w6fw6q 616 7 , , , cord-006870-f5w6fw6q 616 8 73 73 CD cord-006870-f5w6fw6q 616 9 % % NN cord-006870-f5w6fw6q 616 10 were be VBD cord-006870-f5w6fw6q 616 11 men man NNS cord-006870-f5w6fw6q 616 12 , , , cord-006870-f5w6fw6q 616 13 and and CC cord-006870-f5w6fw6q 616 14 median median JJ cord-006870-f5w6fw6q 616 15 motor motor NN cord-006870-f5w6fw6q 616 16 Glasgow Glasgow NNP cord-006870-f5w6fw6q 616 17 - - HYPH cord-006870-f5w6fw6q 616 18 Coma Coma NNP cord-006870-f5w6fw6q 616 19 - - HYPH cord-006870-f5w6fw6q 616 20 Scale Scale NNP cord-006870-f5w6fw6q 616 21 and and CC cord-006870-f5w6fw6q 616 22 Injury injury NN cord-006870-f5w6fw6q 616 23 - - HYPH cord-006870-f5w6fw6q 616 24 Severity severity NN cord-006870-f5w6fw6q 616 25 - - HYPH cord-006870-f5w6fw6q 616 26 Scores score NNS cord-006870-f5w6fw6q 616 27 were be VBD cord-006870-f5w6fw6q 616 28 4 4 CD cord-006870-f5w6fw6q 616 29 ( ( -LRB- cord-006870-f5w6fw6q 616 30 IQR IQR NNP cord-006870-f5w6fw6q 616 31 1;5 1;5 CD cord-006870-f5w6fw6q 616 32 ) ) -RRB- cord-006870-f5w6fw6q 616 33 and and CC cord-006870-f5w6fw6q 616 34 27 27 CD cord-006870-f5w6fw6q 616 35 ( ( -LRB- cord-006870-f5w6fw6q 616 36 IQR IQR NNP cord-006870-f5w6fw6q 616 37 25;38 25;38 CD cord-006870-f5w6fw6q 616 38 ) ) -RRB- cord-006870-f5w6fw6q 616 39 , , , cord-006870-f5w6fw6q 616 40 respectively respectively RB cord-006870-f5w6fw6q 616 41 . . . cord-006870-f5w6fw6q 617 1 The the DT cord-006870-f5w6fw6q 617 2 three three CD cord-006870-f5w6fw6q 617 3 most most RBS cord-006870-f5w6fw6q 617 4 common common JJ cord-006870-f5w6fw6q 617 5 medical medical JJ cord-006870-f5w6fw6q 617 6 and and CC cord-006870-f5w6fw6q 617 7 neurological neurological JJ cord-006870-f5w6fw6q 617 8 ICU ICU NNP cord-006870-f5w6fw6q 617 9 complications complication NNS cord-006870-f5w6fw6q 617 10 were be VBD cord-006870-f5w6fw6q 617 11 : : : cord-006870-f5w6fw6q 617 12 hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 617 13 ( ( -LRB- cord-006870-f5w6fw6q 617 14 83 83 CD cord-006870-f5w6fw6q 617 15 % % NN cord-006870-f5w6fw6q 617 16 ) ) -RRB- cord-006870-f5w6fw6q 617 17 , , , cord-006870-f5w6fw6q 617 18 systemic systemic JJ cord-006870-f5w6fw6q 617 19 inflammatory inflammatory JJ cord-006870-f5w6fw6q 617 20 response response NN cord-006870-f5w6fw6q 617 21 syndrome syndrome NN cord-006870-f5w6fw6q 617 22 ( ( -LRB- cord-006870-f5w6fw6q 617 23 69 69 CD cord-006870-f5w6fw6q 617 24 % % NN cord-006870-f5w6fw6q 617 25 ) ) -RRB- cord-006870-f5w6fw6q 617 26 and and CC cord-006870-f5w6fw6q 617 27 fever fever NN cord-006870-f5w6fw6q 617 28 ( ( -LRB- cord-006870-f5w6fw6q 617 29 66 66 CD cord-006870-f5w6fw6q 617 30 % % NN cord-006870-f5w6fw6q 617 31 ) ) -RRB- cord-006870-f5w6fw6q 617 32 ; ; , cord-006870-f5w6fw6q 617 33 intracranial intracranial JJ cord-006870-f5w6fw6q 617 34 pressure pressure NN cord-006870-f5w6fw6q 617 35 crisis crisis NN cord-006870-f5w6fw6q 617 36 ( ( -LRB- cord-006870-f5w6fw6q 617 37 ICP ICP NNP cord-006870-f5w6fw6q 617 38 ; ; : cord-006870-f5w6fw6q 617 39 [ [ -LRB- cord-006870-f5w6fw6q 617 40 56 56 CD cord-006870-f5w6fw6q 617 41 % % NN cord-006870-f5w6fw6q 617 42 of of IN cord-006870-f5w6fw6q 617 43 n=162 n=162 NNP cord-006870-f5w6fw6q 617 44 with with IN cord-006870-f5w6fw6q 617 45 ICP ICP NNP cord-006870-f5w6fw6q 617 46 - - HYPH cord-006870-f5w6fw6q 617 47 monitor monitor NN cord-006870-f5w6fw6q 617 48 ] ] -RRB- cord-006870-f5w6fw6q 617 49 ) ) -RRB- cord-006870-f5w6fw6q 617 50 , , , cord-006870-f5w6fw6q 617 51 brain brain NN cord-006870-f5w6fw6q 617 52 edema edema NN cord-006870-f5w6fw6q 617 53 requiring require VBG cord-006870-f5w6fw6q 617 54 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 617 55 ( ( -LRB- cord-006870-f5w6fw6q 617 56 46 46 CD cord-006870-f5w6fw6q 617 57 % % NN cord-006870-f5w6fw6q 617 58 ) ) -RRB- cord-006870-f5w6fw6q 617 59 , , , cord-006870-f5w6fw6q 617 60 herniation herniation NN cord-006870-f5w6fw6q 617 61 ( ( -LRB- cord-006870-f5w6fw6q 617 62 45 45 CD cord-006870-f5w6fw6q 617 63 % % NN cord-006870-f5w6fw6q 617 64 ) ) -RRB- cord-006870-f5w6fw6q 617 65 . . . cord-006870-f5w6fw6q 618 1 Multivariable multivariable JJ cord-006870-f5w6fw6q 618 2 models model NNS cord-006870-f5w6fw6q 618 3 were be VBD cord-006870-f5w6fw6q 618 4 adjusted adjust VBN cord-006870-f5w6fw6q 618 5 for for IN cord-006870-f5w6fw6q 618 6 age age NN cord-006870-f5w6fw6q 618 7 , , , cord-006870-f5w6fw6q 618 8 Marshall Marshall NNP cord-006870-f5w6fw6q 618 9 - - HYPH cord-006870-f5w6fw6q 618 10 CT CT NNP cord-006870-f5w6fw6q 618 11 - - HYPH cord-006870-f5w6fw6q 618 12 classification classification NN cord-006870-f5w6fw6q 618 13 , , , cord-006870-f5w6fw6q 618 14 motor motor NN cord-006870-f5w6fw6q 618 15 Glasgow Glasgow NNP cord-006870-f5w6fw6q 618 16 - - HYPH cord-006870-f5w6fw6q 618 17 Coma Coma NNP cord-006870-f5w6fw6q 618 18 - - HYPH cord-006870-f5w6fw6q 618 19 Scale Scale NNP cord-006870-f5w6fw6q 618 20 , , , cord-006870-f5w6fw6q 618 21 pre pre JJ cord-006870-f5w6fw6q 618 22 - - JJ cord-006870-f5w6fw6q 618 23 admission admission JJ cord-006870-f5w6fw6q 618 24 hypotension hypotension NN cord-006870-f5w6fw6q 618 25 , , , cord-006870-f5w6fw6q 618 26 ICU ICU NNP cord-006870-f5w6fw6q 618 27 - - HYPH cord-006870-f5w6fw6q 618 28 length length NN cord-006870-f5w6fw6q 618 29 - - HYPH cord-006870-f5w6fw6q 618 30 of of IN cord-006870-f5w6fw6q 618 31 - - HYPH cord-006870-f5w6fw6q 618 32 stay stay NN cord-006870-f5w6fw6q 618 33 and and CC cord-006870-f5w6fw6q 618 34 Injury injury NN cord-006870-f5w6fw6q 618 35 - - HYPH cord-006870-f5w6fw6q 618 36 Severity severity NN cord-006870-f5w6fw6q 618 37 - - HYPH cord-006870-f5w6fw6q 618 38 Score score NN cord-006870-f5w6fw6q 618 39 . . . cord-006870-f5w6fw6q 619 1 After after IN cord-006870-f5w6fw6q 619 2 adjustment adjustment NN cord-006870-f5w6fw6q 619 3 , , , cord-006870-f5w6fw6q 619 4 in in IN cord-006870-f5w6fw6q 619 5 - - HYPH cord-006870-f5w6fw6q 619 6 hospital hospital NN cord-006870-f5w6fw6q 619 7 mortality mortality NN cord-006870-f5w6fw6q 619 8 was be VBD cord-006870-f5w6fw6q 619 9 significantly significantly RB cord-006870-f5w6fw6q 619 10 associated associate VBN cord-006870-f5w6fw6q 619 11 with with IN cord-006870-f5w6fw6q 619 12 in in IN cord-006870-f5w6fw6q 619 13 - - HYPH cord-006870-f5w6fw6q 619 14 ICU ICU NNP cord-006870-f5w6fw6q 619 15 - - HYPH cord-006870-f5w6fw6q 619 16 cardiacarrest cardiacarr JJS cord-006870-f5w6fw6q 619 17 ( ( -LRB- cord-006870-f5w6fw6q 619 18 OR or CC cord-006870-f5w6fw6q 619 19 23;95%CI 23;95%ci CD cord-006870-f5w6fw6q 619 20 3.5 3.5 CD cord-006870-f5w6fw6q 619 21 - - SYM cord-006870-f5w6fw6q 619 22 152 152 CD cord-006870-f5w6fw6q 619 23 . . . cord-006870-f5w6fw6q 619 24 _SP cord-006870-f5w6fw6q 620 1 Recent recent JJ cord-006870-f5w6fw6q 620 2 studies study NNS cord-006870-f5w6fw6q 620 3 suggest suggest VBP cord-006870-f5w6fw6q 620 4 benefits benefit NNS cord-006870-f5w6fw6q 620 5 for for IN cord-006870-f5w6fw6q 620 6 early early JJ cord-006870-f5w6fw6q 620 7 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 620 8 in in IN cord-006870-f5w6fw6q 620 9 patients patient NNS cord-006870-f5w6fw6q 620 10 with with IN cord-006870-f5w6fw6q 620 11 traumatic traumatic JJ cord-006870-f5w6fw6q 620 12 brain brain NN cord-006870-f5w6fw6q 620 13 injury injury NN cord-006870-f5w6fw6q 620 14 ( ( -LRB- cord-006870-f5w6fw6q 620 15 TBI TBI NNP cord-006870-f5w6fw6q 620 16 ) ) -RRB- cord-006870-f5w6fw6q 620 17 , , , cord-006870-f5w6fw6q 620 18 yet yet CC cord-006870-f5w6fw6q 620 19 data datum NNS cord-006870-f5w6fw6q 620 20 regarding regard VBG cord-006870-f5w6fw6q 620 21 who who WP cord-006870-f5w6fw6q 620 22 will will MD cord-006870-f5w6fw6q 620 23 require require VB cord-006870-f5w6fw6q 620 24 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 620 25 is be VBZ cord-006870-f5w6fw6q 620 26 lacking lack VBG cord-006870-f5w6fw6q 620 27 . . . cord-006870-f5w6fw6q 621 1 ad ad NN cord-006870-f5w6fw6q 621 2 lifesustaining lifesustaine VBG cord-006870-f5w6fw6q 621 3 measures measure NNS cord-006870-f5w6fw6q 621 4 withdrawn withdraw VBN cord-006870-f5w6fw6q 621 5 were be VBD cord-006870-f5w6fw6q 621 6 excluded exclude VBN cord-006870-f5w6fw6q 621 7 . . . cord-006870-f5w6fw6q 622 1 Admission admission NN cord-006870-f5w6fw6q 622 2 and and CC cord-006870-f5w6fw6q 622 3 inpatient inpatient JJ cord-006870-f5w6fw6q 622 4 variables variable NNS cord-006870-f5w6fw6q 622 5 were be VBD cord-006870-f5w6fw6q 622 6 compared compare VBN cord-006870-f5w6fw6q 622 7 . . . cord-006870-f5w6fw6q 623 1 Multivariable multivariable JJ cord-006870-f5w6fw6q 623 2 logistic logistic JJ cord-006870-f5w6fw6q 623 3 regression regression NN cord-006870-f5w6fw6q 623 4 analyses analysis NNS cord-006870-f5w6fw6q 623 5 were be VBD cord-006870-f5w6fw6q 623 6 used use VBN cord-006870-f5w6fw6q 623 7 to to TO cord-006870-f5w6fw6q 623 8 assess assess VB cord-006870-f5w6fw6q 623 9 admission admission NN cord-006870-f5w6fw6q 623 10 and and CC cord-006870-f5w6fw6q 623 11 inpatient inpatient JJ cord-006870-f5w6fw6q 623 12 factors factor NNS cord-006870-f5w6fw6q 623 13 associated associate VBN cord-006870-f5w6fw6q 623 14 with with IN cord-006870-f5w6fw6q 623 15 receiving receive VBG cord-006870-f5w6fw6q 623 16 a a DT cord-006870-f5w6fw6q 623 17 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 623 18 and and CC cord-006870-f5w6fw6q 623 19 to to TO cord-006870-f5w6fw6q 623 20 develop develop VB cord-006870-f5w6fw6q 623 21 models model NNS cord-006870-f5w6fw6q 623 22 predictive predictive JJ cord-006870-f5w6fw6q 623 23 of of IN cord-006870-f5w6fw6q 623 24 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 623 25 . . . cord-006870-f5w6fw6q 624 1 There there EX cord-006870-f5w6fw6q 624 2 were be VBD cord-006870-f5w6fw6q 624 3 209 209 CD cord-006870-f5w6fw6q 624 4 patients patient NNS cord-006870-f5w6fw6q 624 5 ( ( -LRB- cord-006870-f5w6fw6q 624 6 78 78 CD cord-006870-f5w6fw6q 624 7 % % NN cord-006870-f5w6fw6q 624 8 men man NNS cord-006870-f5w6fw6q 624 9 , , , cord-006870-f5w6fw6q 624 10 mean mean VBP cord-006870-f5w6fw6q 624 11 48 48 CD cord-006870-f5w6fw6q 624 12 years year NNS cord-006870-f5w6fw6q 624 13 - - HYPH cord-006870-f5w6fw6q 624 14 old old JJ cord-006870-f5w6fw6q 624 15 , , , cord-006870-f5w6fw6q 624 16 median median JJ cord-006870-f5w6fw6q 624 17 GCS GCS NNP cord-006870-f5w6fw6q 624 18 8) 8) NNP cord-006870-f5w6fw6q 624 19 meeting meeting NN cord-006870-f5w6fw6q 624 20 study study NN cord-006870-f5w6fw6q 624 21 criteria criterion NNS cord-006870-f5w6fw6q 624 22 with with IN cord-006870-f5w6fw6q 624 23 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 624 24 performed perform VBN cord-006870-f5w6fw6q 624 25 in in IN cord-006870-f5w6fw6q 624 26 94 94 CD cord-006870-f5w6fw6q 624 27 ( ( -LRB- cord-006870-f5w6fw6q 624 28 45 45 CD cord-006870-f5w6fw6q 624 29 % % NN cord-006870-f5w6fw6q 624 30 ) ) -RRB- cord-006870-f5w6fw6q 624 31 . . . cord-006870-f5w6fw6q 625 1 Admission admission NN cord-006870-f5w6fw6q 625 2 predictors predictor NNS cord-006870-f5w6fw6q 625 3 of of IN cord-006870-f5w6fw6q 625 4 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 625 5 included include VBD cord-006870-f5w6fw6q 625 6 GCS GCS NNP cord-006870-f5w6fw6q 625 7 , , , cord-006870-f5w6fw6q 625 8 Marshall Marshall NNP cord-006870-f5w6fw6q 625 9 score score NN cord-006870-f5w6fw6q 625 10 , , , cord-006870-f5w6fw6q 625 11 injury injury NN cord-006870-f5w6fw6q 625 12 mechanism mechanism NN cord-006870-f5w6fw6q 625 13 , , , cord-006870-f5w6fw6q 625 14 PaO2 PaO2 NNS cord-006870-f5w6fw6q 625 15 / / SYM cord-006870-f5w6fw6q 625 16 FiO2 FiO2 NNS cord-006870-f5w6fw6q 625 17 ratio ratio NN cord-006870-f5w6fw6q 625 18 , , , cord-006870-f5w6fw6q 625 19 and and CC cord-006870-f5w6fw6q 625 20 number number NN cord-006870-f5w6fw6q 625 21 of of IN cord-006870-f5w6fw6q 625 22 quadrants quadrant NNS cord-006870-f5w6fw6q 625 23 on on IN cord-006870-f5w6fw6q 625 24 chest chest NN cord-006870-f5w6fw6q 625 25 x x NN cord-006870-f5w6fw6q 625 26 - - NN cord-006870-f5w6fw6q 625 27 ray ray NN cord-006870-f5w6fw6q 625 28 with with IN cord-006870-f5w6fw6q 625 29 consolidation consolidation NN cord-006870-f5w6fw6q 625 30 . . . cord-006870-f5w6fw6q 626 1 Inpatient inpatient JJ cord-006870-f5w6fw6q 626 2 factors factor NNS cord-006870-f5w6fw6q 626 3 associated associate VBN cord-006870-f5w6fw6q 626 4 with with IN cord-006870-f5w6fw6q 626 5 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 626 6 included include VBD cord-006870-f5w6fw6q 626 7 the the DT cord-006870-f5w6fw6q 626 8 requirement requirement NN cord-006870-f5w6fw6q 626 9 for for IN cord-006870-f5w6fw6q 626 10 an an DT cord-006870-f5w6fw6q 626 11 external external JJ cord-006870-f5w6fw6q 626 12 ventricular ventricular JJ cord-006870-f5w6fw6q 626 13 drain drain NN cord-006870-f5w6fw6q 626 14 ( ( -LRB- cord-006870-f5w6fw6q 626 15 EVD EVD NNP cord-006870-f5w6fw6q 626 16 ) ) -RRB- cord-006870-f5w6fw6q 626 17 , , , cord-006870-f5w6fw6q 626 18 number number NN cord-006870-f5w6fw6q 626 19 of of IN cord-006870-f5w6fw6q 626 20 operations operation NNS cord-006870-f5w6fw6q 626 21 , , , cord-006870-f5w6fw6q 626 22 pneumothorax pneumothorax NN cord-006870-f5w6fw6q 626 23 , , , cord-006870-f5w6fw6q 626 24 inpatient inpatient JJ cord-006870-f5w6fw6q 626 25 dialysis dialysis NN cord-006870-f5w6fw6q 626 26 , , , cord-006870-f5w6fw6q 626 27 aspiration aspiration NN cord-006870-f5w6fw6q 626 28 , , , cord-006870-f5w6fw6q 626 29 reintubation reintubation NN cord-006870-f5w6fw6q 626 30 , , , cord-006870-f5w6fw6q 626 31 and and CC cord-006870-f5w6fw6q 626 32 the the DT cord-006870-f5w6fw6q 626 33 presence presence NN cord-006870-f5w6fw6q 626 34 of of IN cord-006870-f5w6fw6q 626 35 hospital hospital NN cord-006870-f5w6fw6q 626 36 acquired acquire VBN cord-006870-f5w6fw6q 626 37 infections infection NNS cord-006870-f5w6fw6q 626 38 . . . cord-006870-f5w6fw6q 627 1 Multiple multiple JJ cord-006870-f5w6fw6q 627 2 logistic logistic JJ cord-006870-f5w6fw6q 627 3 regression regression NN cord-006870-f5w6fw6q 627 4 analysis analysis NN cord-006870-f5w6fw6q 627 5 demonstrated demonstrate VBD cord-006870-f5w6fw6q 627 6 that that IN cord-006870-f5w6fw6q 627 7 the the DT cord-006870-f5w6fw6q 627 8 development development NN cord-006870-f5w6fw6q 627 9 of of IN cord-006870-f5w6fw6q 627 10 hospital hospital NN cord-006870-f5w6fw6q 627 11 acquired acquire VBN cord-006870-f5w6fw6q 627 12 infection infection NN cord-006870-f5w6fw6q 627 13 ( ( -LRB- cord-006870-f5w6fw6q 627 14 adjusted adjust VBN cord-006870-f5w6fw6q 627 15 odds odd NNS cord-006870-f5w6fw6q 627 16 ratio ratio NN cord-006870-f5w6fw6q 627 17 [ [ -LRB- cord-006870-f5w6fw6q 627 18 AOR AOR NNP cord-006870-f5w6fw6q 627 19 ] ] -RRB- cord-006870-f5w6fw6q 627 20 , , , cord-006870-f5w6fw6q 627 21 4.78 4.78 CD cord-006870-f5w6fw6q 627 22 ; ; : cord-006870-f5w6fw6q 627 23 95 95 CD cord-006870-f5w6fw6q 627 24 % % NN cord-006870-f5w6fw6q 627 25 confidence confidence NN cord-006870-f5w6fw6q 627 26 interval interval NN cord-006870-f5w6fw6q 627 27 [ [ -LRB- cord-006870-f5w6fw6q 627 28 CI CI NNP cord-006870-f5w6fw6q 627 29 ] ] -RRB- cord-006870-f5w6fw6q 627 30 , , , cord-006870-f5w6fw6q 627 31 2.18 2.18 CD cord-006870-f5w6fw6q 627 32 - - SYM cord-006870-f5w6fw6q 627 33 10.48 10.48 CD cord-006870-f5w6fw6q 627 34 ; ; : cord-006870-f5w6fw6q 627 35 p p NN cord-006870-f5w6fw6q 627 36 < < XX cord-006870-f5w6fw6q 627 37 .001 .001 CD cord-006870-f5w6fw6q 627 38 ) ) -RRB- cord-006870-f5w6fw6q 627 39 , , , cord-006870-f5w6fw6q 627 40 number number NN cord-006870-f5w6fw6q 627 41 of of IN cord-006870-f5w6fw6q 627 42 operations operation NNS cord-006870-f5w6fw6q 627 43 ( ( -LRB- cord-006870-f5w6fw6q 627 44 AOR AOR NNP cord-006870-f5w6fw6q 627 45 , , , cord-006870-f5w6fw6q 627 46 1.47 1.47 CD cord-006870-f5w6fw6q 627 47 ; ; : cord-006870-f5w6fw6q 627 48 95 95 CD cord-006870-f5w6fw6q 627 49 % % NN cord-006870-f5w6fw6q 627 50 CI CI NNP cord-006870-f5w6fw6q 627 51 , , , cord-006870-f5w6fw6q 627 52 1.2 1.2 CD cord-006870-f5w6fw6q 627 53 - - SYM cord-006870-f5w6fw6q 627 54 1.78 1.78 CD cord-006870-f5w6fw6q 627 55 ; ; : cord-006870-f5w6fw6q 627 56 p p NN cord-006870-f5w6fw6q 627 57 < < XX cord-006870-f5w6fw6q 627 58 .001 .001 CD cord-006870-f5w6fw6q 627 59 ) ) -RRB- cord-006870-f5w6fw6q 627 60 , , , cord-006870-f5w6fw6q 627 61 pneumothorax pneumothorax NN cord-006870-f5w6fw6q 627 62 ( ( -LRB- cord-006870-f5w6fw6q 627 63 AOR AOR NNP cord-006870-f5w6fw6q 627 64 , , , cord-006870-f5w6fw6q 627 65 2.64 2.64 CD cord-006870-f5w6fw6q 627 66 ; ; : cord-006870-f5w6fw6q 627 67 95 95 CD cord-006870-f5w6fw6q 627 68 % % NN cord-006870-f5w6fw6q 627 69 CI CI NNP cord-006870-f5w6fw6q 627 70 , , , cord-006870-f5w6fw6q 627 71 1.08 1.08 CD cord-006870-f5w6fw6q 627 72 - - SYM cord-006870-f5w6fw6q 627 73 6.48 6.48 CD cord-006870-f5w6fw6q 627 74 ; ; : cord-006870-f5w6fw6q 627 75 p p NN cord-006870-f5w6fw6q 627 76 = = SYM cord-006870-f5w6fw6q 627 77 .034 .034 CD cord-006870-f5w6fw6q 627 78 ) ) -RRB- cord-006870-f5w6fw6q 627 79 , , , cord-006870-f5w6fw6q 627 80 reintubation reintubation NN cord-006870-f5w6fw6q 627 81 ( ( -LRB- cord-006870-f5w6fw6q 627 82 AOR AOR NNP cord-006870-f5w6fw6q 627 83 , , , cord-006870-f5w6fw6q 627 84 7.18 7.18 CD cord-006870-f5w6fw6q 627 85 ; ; : cord-006870-f5w6fw6q 627 86 95 95 CD cord-006870-f5w6fw6q 627 87 % % NN cord-006870-f5w6fw6q 627 88 CI CI NNP cord-006870-f5w6fw6q 627 89 , , , cord-006870-f5w6fw6q 627 90 2.50 2.50 CD cord-006870-f5w6fw6q 627 91 - - SYM cord-006870-f5w6fw6q 627 92 20.54 20.54 CD cord-006870-f5w6fw6q 627 93 ; ; : cord-006870-f5w6fw6q 627 94 < < XX cord-006870-f5w6fw6q 627 95 .001 .001 CD cord-006870-f5w6fw6q 627 96 ) ) -RRB- cord-006870-f5w6fw6q 627 97 , , , cord-006870-f5w6fw6q 627 98 penetrating penetrate VBG cord-006870-f5w6fw6q 627 99 TBI TBI NNP cord-006870-f5w6fw6q 627 100 ( ( -LRB- cord-006870-f5w6fw6q 627 101 AOR AOR NNP cord-006870-f5w6fw6q 627 102 , , , cord-006870-f5w6fw6q 627 103 0.14 0.14 CD cord-006870-f5w6fw6q 627 104 ; ; : cord-006870-f5w6fw6q 627 105 95 95 CD cord-006870-f5w6fw6q 627 106 % % NN cord-006870-f5w6fw6q 627 107 CI ci NN cord-006870-f5w6fw6q 627 108 , , , cord-006870-f5w6fw6q 627 109 0.03 0.03 CD cord-006870-f5w6fw6q 627 110 - - SYM cord-006870-f5w6fw6q 627 111 0.60 0.60 CD cord-006870-f5w6fw6q 627 112 ; ; : cord-006870-f5w6fw6q 627 113 p=0.008 p=0.008 NNP cord-006870-f5w6fw6q 627 114 ) ) -RRB- cord-006870-f5w6fw6q 627 115 and and CC cord-006870-f5w6fw6q 627 116 placement placement NN cord-006870-f5w6fw6q 627 117 of of IN cord-006870-f5w6fw6q 627 118 EVD EVD NNP cord-006870-f5w6fw6q 627 119 ( ( -LRB- cord-006870-f5w6fw6q 627 120 AOR AOR NNP cord-006870-f5w6fw6q 627 121 , , , cord-006870-f5w6fw6q 627 122 6.73 6.73 CD cord-006870-f5w6fw6q 627 123 ; ; : cord-006870-f5w6fw6q 627 124 95 95 CD cord-006870-f5w6fw6q 627 125 % % NN cord-006870-f5w6fw6q 627 126 CI CI NNP cord-006870-f5w6fw6q 627 127 , , , cord-006870-f5w6fw6q 627 128 3.03 3.03 CD cord-006870-f5w6fw6q 627 129 - - SYM cord-006870-f5w6fw6q 627 130 14.95 14.95 CD cord-006870-f5w6fw6q 627 131 ; ; : cord-006870-f5w6fw6q 627 132 < < XX cord-006870-f5w6fw6q 627 133 .001 .001 CD cord-006870-f5w6fw6q 627 134 ) ) -RRB- cord-006870-f5w6fw6q 627 135 were be VBD cord-006870-f5w6fw6q 627 136 independently independently RB cord-006870-f5w6fw6q 627 137 associated associate VBN cord-006870-f5w6fw6q 627 138 with with IN cord-006870-f5w6fw6q 627 139 patients patient NNS cord-006870-f5w6fw6q 627 140 undergoing undergo VBG cord-006870-f5w6fw6q 627 141 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 627 142 . . . cord-006870-f5w6fw6q 628 1 A a DT cord-006870-f5w6fw6q 628 2 model model NN cord-006870-f5w6fw6q 628 3 of of IN cord-006870-f5w6fw6q 628 4 inpatient inpatient JJ cord-006870-f5w6fw6q 628 5 variables variable NNS cord-006870-f5w6fw6q 628 6 only only RB cord-006870-f5w6fw6q 628 7 was be VBD cord-006870-f5w6fw6q 628 8 more more RBR cord-006870-f5w6fw6q 628 9 strongly strongly RB cord-006870-f5w6fw6q 628 10 associated associate VBN cord-006870-f5w6fw6q 628 11 with with IN cord-006870-f5w6fw6q 628 12 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 628 13 than than IN cord-006870-f5w6fw6q 628 14 one one CD cord-006870-f5w6fw6q 628 15 with with IN cord-006870-f5w6fw6q 628 16 admission admission NN cord-006870-f5w6fw6q 628 17 variables variable NNS cord-006870-f5w6fw6q 628 18 only only RB cord-006870-f5w6fw6q 628 19 ( ( -LRB- cord-006870-f5w6fw6q 628 20 ROC ROC NNP cord-006870-f5w6fw6q 628 21 AUC AUC NNP cord-006870-f5w6fw6q 628 22 0.90 0.90 CD cord-006870-f5w6fw6q 628 23 vs. vs. IN cord-006870-f5w6fw6q 628 24 0.72 0.72 CD cord-006870-f5w6fw6q 628 25 , , , cord-006870-f5w6fw6q 628 26 P<0.001 P<0.001 NNP cord-006870-f5w6fw6q 628 27 ) ) -RRB- cord-006870-f5w6fw6q 628 28 and and CC cord-006870-f5w6fw6q 628 29 did do VBD cord-006870-f5w6fw6q 628 30 not not RB cord-006870-f5w6fw6q 628 31 benefit benefit VB cord-006870-f5w6fw6q 628 32 from from IN cord-006870-f5w6fw6q 628 33 addition addition NN cord-006870-f5w6fw6q 628 34 of of IN cord-006870-f5w6fw6q 628 35 admission admission NN cord-006870-f5w6fw6q 628 36 variables variable NNS cord-006870-f5w6fw6q 628 37 ( ( -LRB- cord-006870-f5w6fw6q 628 38 ROC ROC NNP cord-006870-f5w6fw6q 628 39 AUC AUC NNP cord-006870-f5w6fw6q 628 40 0.91 0.91 CD cord-006870-f5w6fw6q 628 41 vs vs IN cord-006870-f5w6fw6q 628 42 0.90 0.90 CD cord-006870-f5w6fw6q 628 43 , , , cord-006870-f5w6fw6q 628 44 P=0.76 P=0.76 NNP cord-006870-f5w6fw6q 628 45 ) ) -RRB- cord-006870-f5w6fw6q 628 46 . . . cord-006870-f5w6fw6q 629 1 Potentially potentially RB cord-006870-f5w6fw6q 629 2 modifiable modifiable JJ cord-006870-f5w6fw6q 629 3 inpatient inpatient JJ cord-006870-f5w6fw6q 629 4 factors factor NNS cord-006870-f5w6fw6q 629 5 have have VBP cord-006870-f5w6fw6q 629 6 a a DT cord-006870-f5w6fw6q 629 7 stronger strong JJR cord-006870-f5w6fw6q 629 8 association association NN cord-006870-f5w6fw6q 629 9 with with IN cord-006870-f5w6fw6q 629 10 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 629 11 than than IN cord-006870-f5w6fw6q 629 12 do do VB cord-006870-f5w6fw6q 629 13 admission admission NN cord-006870-f5w6fw6q 629 14 characteristics characteristic NNS cord-006870-f5w6fw6q 629 15 . . . cord-006870-f5w6fw6q 630 1 Existing exist VBG cord-006870-f5w6fw6q 630 2 traumatic traumatic JJ cord-006870-f5w6fw6q 630 3 brain brain NN cord-006870-f5w6fw6q 630 4 injury injury NN cord-006870-f5w6fw6q 630 5 ( ( -LRB- cord-006870-f5w6fw6q 630 6 TBI TBI NNP cord-006870-f5w6fw6q 630 7 ) ) -RRB- cord-006870-f5w6fw6q 630 8 guidelines guideline NNS cord-006870-f5w6fw6q 630 9 are be VBP cord-006870-f5w6fw6q 630 10 designed design VBN cord-006870-f5w6fw6q 630 11 primarily primarily RB cord-006870-f5w6fw6q 630 12 for for IN cord-006870-f5w6fw6q 630 13 the the DT cord-006870-f5w6fw6q 630 14 evaluation evaluation NN cord-006870-f5w6fw6q 630 15 and and CC cord-006870-f5w6fw6q 630 16 management management NN cord-006870-f5w6fw6q 630 17 of of IN cord-006870-f5w6fw6q 630 18 TBI TBI NNP cord-006870-f5w6fw6q 630 19 in in IN cord-006870-f5w6fw6q 630 20 tertiary tertiary JJ cord-006870-f5w6fw6q 630 21 care care NN cord-006870-f5w6fw6q 630 22 centers center NNS cord-006870-f5w6fw6q 630 23 with with IN cord-006870-f5w6fw6q 630 24 advanced advanced JJ cord-006870-f5w6fw6q 630 25 neuroscience neuroscience NN cord-006870-f5w6fw6q 630 26 capabilities capability NNS cord-006870-f5w6fw6q 630 27 . . . cord-006870-f5w6fw6q 631 1 Military Military NNP cord-006870-f5w6fw6q 631 2 Special Special NNP cord-006870-f5w6fw6q 631 3 Operations Operations NNP cord-006870-f5w6fw6q 631 4 medical medical JJ cord-006870-f5w6fw6q 631 5 providers provider NNS cord-006870-f5w6fw6q 631 6 , , , cord-006870-f5w6fw6q 631 7 however however RB cord-006870-f5w6fw6q 631 8 , , , cord-006870-f5w6fw6q 631 9 are be VBP cord-006870-f5w6fw6q 631 10 often often RB cord-006870-f5w6fw6q 631 11 required require VBN cord-006870-f5w6fw6q 631 12 to to TO cord-006870-f5w6fw6q 631 13 treat treat VB cord-006870-f5w6fw6q 631 14 and and CC cord-006870-f5w6fw6q 631 15 sustain sustain VB cord-006870-f5w6fw6q 631 16 patients patient NNS cord-006870-f5w6fw6q 631 17 in in IN cord-006870-f5w6fw6q 631 18 austere austere JJ cord-006870-f5w6fw6q 631 19 environments environment NNS cord-006870-f5w6fw6q 631 20 with with IN cord-006870-f5w6fw6q 631 21 limited limited JJ cord-006870-f5w6fw6q 631 22 resources resource NNS cord-006870-f5w6fw6q 631 23 for for IN cord-006870-f5w6fw6q 631 24 up up IN cord-006870-f5w6fw6q 631 25 to to TO cord-006870-f5w6fw6q 631 26 72 72 CD cord-006870-f5w6fw6q 631 27 hours hour NNS cord-006870-f5w6fw6q 631 28 . . . cord-006870-f5w6fw6q 632 1 TBI TBI NNP cord-006870-f5w6fw6q 632 2 management management NN cord-006870-f5w6fw6q 632 3 guidelines guideline NNS cord-006870-f5w6fw6q 632 4 directed direct VBN cord-006870-f5w6fw6q 632 5 specifically specifically RB cord-006870-f5w6fw6q 632 6 toward toward IN cord-006870-f5w6fw6q 632 7 the the DT cord-006870-f5w6fw6q 632 8 care care NN cord-006870-f5w6fw6q 632 9 of of IN cord-006870-f5w6fw6q 632 10 these these DT cord-006870-f5w6fw6q 632 11 patients patient NNS cord-006870-f5w6fw6q 632 12 are be VBP cord-006870-f5w6fw6q 632 13 needed need VBN cord-006870-f5w6fw6q 632 14 . . . cord-006870-f5w6fw6q 633 1 A a DT cord-006870-f5w6fw6q 633 2 review review NN cord-006870-f5w6fw6q 633 3 of of IN cord-006870-f5w6fw6q 633 4 recent recent JJ cord-006870-f5w6fw6q 633 5 operational operational JJ cord-006870-f5w6fw6q 633 6 experiences experience NNS cord-006870-f5w6fw6q 633 7 involving involve VBG cord-006870-f5w6fw6q 633 8 TBI TBI NNP cord-006870-f5w6fw6q 633 9 and and CC cord-006870-f5w6fw6q 633 10 a a DT cord-006870-f5w6fw6q 633 11 survey survey NN cord-006870-f5w6fw6q 633 12 of of IN cord-006870-f5w6fw6q 633 13 Military Military NNP cord-006870-f5w6fw6q 633 14 Special Special NNP cord-006870-f5w6fw6q 633 15 Operations Operations NNPS cord-006870-f5w6fw6q 633 16 Medics Medics NNPS cord-006870-f5w6fw6q 633 17 prompted prompt VBD cord-006870-f5w6fw6q 633 18 a a DT cord-006870-f5w6fw6q 633 19 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 633 20 Expert Expert NNP cord-006870-f5w6fw6q 633 21 Panel Panel NNP cord-006870-f5w6fw6q 633 22 to to TO cord-006870-f5w6fw6q 633 23 develop develop VB cord-006870-f5w6fw6q 633 24 draft draft NN cord-006870-f5w6fw6q 633 25 clinical clinical JJ cord-006870-f5w6fw6q 633 26 practice practice NN cord-006870-f5w6fw6q 633 27 guidelines guideline NNS cord-006870-f5w6fw6q 633 28 / / SYM cord-006870-f5w6fw6q 633 29 recommendations recommendation NNS cord-006870-f5w6fw6q 633 30 for for IN cord-006870-f5w6fw6q 633 31 prolonged prolonged JJ cord-006870-f5w6fw6q 633 32 field field NN cord-006870-f5w6fw6q 633 33 management management NN cord-006870-f5w6fw6q 633 34 of of IN cord-006870-f5w6fw6q 633 35 TBI TBI NNP cord-006870-f5w6fw6q 633 36 . . . cord-006870-f5w6fw6q 634 1 The the DT cord-006870-f5w6fw6q 634 2 panel panel NN cord-006870-f5w6fw6q 634 3 conducted conduct VBD cord-006870-f5w6fw6q 634 4 an an DT cord-006870-f5w6fw6q 634 5 in in IN cord-006870-f5w6fw6q 634 6 - - HYPH cord-006870-f5w6fw6q 634 7 depth depth NN cord-006870-f5w6fw6q 634 8 review review NN cord-006870-f5w6fw6q 634 9 of of IN cord-006870-f5w6fw6q 634 10 literature literature NN cord-006870-f5w6fw6q 634 11 on on IN cord-006870-f5w6fw6q 634 12 TBI TBI NNP cord-006870-f5w6fw6q 634 13 and and CC cord-006870-f5w6fw6q 634 14 related relate VBN cord-006870-f5w6fw6q 634 15 topics topic NNS cord-006870-f5w6fw6q 634 16 and and CC cord-006870-f5w6fw6q 634 17 adapted adapt VBN cord-006870-f5w6fw6q 634 18 existing exist VBG cord-006870-f5w6fw6q 634 19 and and CC cord-006870-f5w6fw6q 634 20 emerging emerge VBG cord-006870-f5w6fw6q 634 21 therapies therapy NNS cord-006870-f5w6fw6q 634 22 to to TO cord-006870-f5w6fw6q 634 23 address address VB cord-006870-f5w6fw6q 634 24 the the DT cord-006870-f5w6fw6q 634 25 unique unique JJ cord-006870-f5w6fw6q 634 26 challenges challenge NNS cord-006870-f5w6fw6q 634 27 encountered encounter VBN cord-006870-f5w6fw6q 634 28 in in IN cord-006870-f5w6fw6q 634 29 prolonged prolonged JJ cord-006870-f5w6fw6q 634 30 field field NN cord-006870-f5w6fw6q 634 31 care care NN cord-006870-f5w6fw6q 634 32 . . . cord-006870-f5w6fw6q 635 1 TBI TBI NNP cord-006870-f5w6fw6q 635 2 management management NN cord-006870-f5w6fw6q 635 3 while while IN cord-006870-f5w6fw6q 635 4 optimal optimal JJ cord-006870-f5w6fw6q 635 5 management management NN cord-006870-f5w6fw6q 635 6 of of IN cord-006870-f5w6fw6q 635 7 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 635 8 is be VBZ cord-006870-f5w6fw6q 635 9 not not RB cord-006870-f5w6fw6q 635 10 fully fully RB cord-006870-f5w6fw6q 635 11 established establish VBN cord-006870-f5w6fw6q 635 12 . . . cord-006870-f5w6fw6q 636 1 The the DT cord-006870-f5w6fw6q 636 2 objective objective NN cord-006870-f5w6fw6q 636 3 of of IN cord-006870-f5w6fw6q 636 4 this this DT cord-006870-f5w6fw6q 636 5 -Coeur -Coeur NNP cord-006870-f5w6fw6q 636 6 arterial arterial JJ cord-006870-f5w6fw6q 636 7 blood blood NN cord-006870-f5w6fw6q 636 8 gas gas NN cord-006870-f5w6fw6q 636 9 was be VBD cord-006870-f5w6fw6q 636 10 drawn draw VBN cord-006870-f5w6fw6q 636 11 ( ( -LRB- cord-006870-f5w6fw6q 636 12 ICP ICP NNP cord-006870-f5w6fw6q 636 13 , , , cord-006870-f5w6fw6q 636 14 CPP CPP NNP cord-006870-f5w6fw6q 636 15 , , , cord-006870-f5w6fw6q 636 16 hemoglobin hemoglobin NN cord-006870-f5w6fw6q 636 17 , , , cord-006870-f5w6fw6q 636 18 temperature temperature NN cord-006870-f5w6fw6q 636 19 , , , cord-006870-f5w6fw6q 636 20 PCO2 PCO2 NNP cord-006870-f5w6fw6q 636 21 and and CC cord-006870-f5w6fw6q 636 22 PaO2 PaO2 NNS cord-006870-f5w6fw6q 636 23 ) ) -RRB- cord-006870-f5w6fw6q 636 24 . . . cord-006870-f5w6fw6q 637 1 Probes probe NNS cord-006870-f5w6fw6q 637 2 were be VBD cord-006870-f5w6fw6q 637 3 localized localize VBN cord-006870-f5w6fw6q 637 4 in in IN cord-006870-f5w6fw6q 637 5 normal normal JJ cord-006870-f5w6fw6q 637 6 appearing appear VBG cord-006870-f5w6fw6q 637 7 white white JJ cord-006870-f5w6fw6q 637 8 matter matter NN cord-006870-f5w6fw6q 637 9 . . . cord-006870-f5w6fw6q 638 1 We -PRON- PRP cord-006870-f5w6fw6q 638 2 used use VBD cord-006870-f5w6fw6q 638 3 a a DT cord-006870-f5w6fw6q 638 4 was be VBD cord-006870-f5w6fw6q 638 5 calculated calculate VBN cord-006870-f5w6fw6q 638 6 . . . cord-006870-f5w6fw6q 639 1 A a DT cord-006870-f5w6fw6q 639 2 total total NN cord-006870-f5w6fw6q 639 3 of of IN cord-006870-f5w6fw6q 639 4 1006 1006 CD cord-006870-f5w6fw6q 639 5 data data NN cord-006870-f5w6fw6q 639 6 sets set NNS cord-006870-f5w6fw6q 639 7 were be VBD cord-006870-f5w6fw6q 639 8 collected collect VBN cord-006870-f5w6fw6q 639 9 from from IN cord-006870-f5w6fw6q 639 10 38 38 CD cord-006870-f5w6fw6q 639 11 patients patient NNS cord-006870-f5w6fw6q 639 12 ( ( -LRB- cord-006870-f5w6fw6q 639 13 mean mean VB cord-006870-f5w6fw6q 639 14 age age NN cord-006870-f5w6fw6q 639 15 44.5±20.0 44.5±20.0 CD cord-006870-f5w6fw6q 639 16 , , , cord-006870-f5w6fw6q 639 17 median median JJ cord-006870-f5w6fw6q 639 18 GCS GCS NNP cord-006870-f5w6fw6q 639 19 4 4 CD cord-006870-f5w6fw6q 639 20 , , , cord-006870-f5w6fw6q 639 21 mortality mortality NN cord-006870-f5w6fw6q 639 22 range range NN cord-006870-f5w6fw6q 639 23 from from IN cord-006870-f5w6fw6q 639 24 94 94 CD cord-006870-f5w6fw6q 639 25 to to IN cord-006870-f5w6fw6q 639 26 400 400 CD cord-006870-f5w6fw6q 639 27 ) ) -RRB- cord-006870-f5w6fw6q 639 28 . . . cord-006870-f5w6fw6q 640 1 Mean mean JJ cord-006870-f5w6fw6q 640 2 PaO2 PaO2 NNS cord-006870-f5w6fw6q 640 3 for for IN cord-006870-f5w6fw6q 640 4 the the DT cord-006870-f5w6fw6q 640 5 group group NN cord-006870-f5w6fw6q 640 6 as as IN cord-006870-f5w6fw6q 640 7 a a DT cord-006870-f5w6fw6q 640 8 whole whole NN cord-006870-f5w6fw6q 640 9 was be VBD cord-006870-f5w6fw6q 640 10 178 178 CD cord-006870-f5w6fw6q 640 11 mmHg mmHg NNS cord-006870-f5w6fw6q 640 12 ( ( -LRB- cord-006870-f5w6fw6q 640 13 ± ± NNP cord-006870-f5w6fw6q 640 14 88 88 CD cord-006870-f5w6fw6q 640 15 ) ) -RRB- cord-006870-f5w6fw6q 640 16 and and CC cord-006870-f5w6fw6q 640 17 mean mean VB cord-006870-f5w6fw6q 640 18 CPP CPP NNP cord-006870-f5w6fw6q 640 19 was be VBD cord-006870-f5w6fw6q 640 20 72 72 CD cord-006870-f5w6fw6q 640 21 mmHg mmHg NNS cord-006870-f5w6fw6q 640 22 ( ( -LRB- cord-006870-f5w6fw6q 640 23 ± ± NNP cord-006870-f5w6fw6q 640 24 12 12 CD cord-006870-f5w6fw6q 640 25 ) ) -RRB- cord-006870-f5w6fw6q 640 26 . . . cord-006870-f5w6fw6q 641 1 Mean mean JJ cord-006870-f5w6fw6q 641 2 duration duration NN cord-006870-f5w6fw6q 641 3 of of IN cord-006870-f5w6fw6q 641 4 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 641 5 monitoring monitoring NN cord-006870-f5w6fw6q 641 6 was be VBD cord-006870-f5w6fw6q 641 7 6.5 6.5 CD cord-006870-f5w6fw6q 641 8 days day NNS cord-006870-f5w6fw6q 641 9 ( ( -LRB- cord-006870-f5w6fw6q 641 10 ± ± CD cord-006870-f5w6fw6q 641 11 3.7 3.7 CD cord-006870-f5w6fw6q 641 12 ) ) -RRB- cord-006870-f5w6fw6q 641 13 . . . cord-006870-f5w6fw6q 642 1 Taking take VBG cord-006870-f5w6fw6q 642 2 into into IN cord-006870-f5w6fw6q 642 3 account account NN cord-006870-f5w6fw6q 642 4 all all DT cord-006870-f5w6fw6q 642 5 determinants determinant NNS cord-006870-f5w6fw6q 642 6 of of IN cord-006870-f5w6fw6q 642 7 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 642 8 and and CC cord-006870-f5w6fw6q 642 9 using use VBG cord-006870-f5w6fw6q 642 10 a a DT cord-006870-f5w6fw6q 642 11 protocolized protocolized JJ cord-006870-f5w6fw6q 642 12 approach approach NN cord-006870-f5w6fw6q 642 13 to to TO cord-006870-f5w6fw6q 642 14 correct correct VB cord-006870-f5w6fw6q 642 15 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 642 16 , , , cord-006870-f5w6fw6q 642 17 the the DT cord-006870-f5w6fw6q 642 18 mmHg mmHg NNS cord-006870-f5w6fw6q 642 19 for for IN cord-006870-f5w6fw6q 642 20 a a DT cord-006870-f5w6fw6q 642 21 few few JJ cord-006870-f5w6fw6q 642 22 days day NNS cord-006870-f5w6fw6q 642 23 . . . cord-006870-f5w6fw6q 643 1 High high JJ cord-006870-f5w6fw6q 643 2 PaO2 pao2 JJ cord-006870-f5w6fw6q 643 3 values value NNS cord-006870-f5w6fw6q 643 4 are be VBP cord-006870-f5w6fw6q 643 5 possibly possibly RB cord-006870-f5w6fw6q 643 6 required require VBN cord-006870-f5w6fw6q 643 7 due due IN cord-006870-f5w6fw6q 643 8 to to IN cord-006870-f5w6fw6q 643 9 the the DT cord-006870-f5w6fw6q 643 10 fact fact NN cord-006870-f5w6fw6q 643 11 that that IN cord-006870-f5w6fw6q 643 12 oxygen oxygen NN cord-006870-f5w6fw6q 643 13 delivery delivery NN cord-006870-f5w6fw6q 643 14 to to IN cord-006870-f5w6fw6q 643 15 the the DT cord-006870-f5w6fw6q 643 16 brain brain NN cord-006870-f5w6fw6q 643 17 is be VBZ cord-006870-f5w6fw6q 643 18 rate rate NN cord-006870-f5w6fw6q 643 19 - - HYPH cord-006870-f5w6fw6q 643 20 limited limit VBN cord-006870-f5w6fw6q 643 21 by by IN cord-006870-f5w6fw6q 643 22 diffusion diffusion NN cord-006870-f5w6fw6q 643 23 and and CC cord-006870-f5w6fw6q 643 24 impaired impair VBN cord-006870-f5w6fw6q 643 25 by by IN cord-006870-f5w6fw6q 643 26 oedema oedema NN cord-006870-f5w6fw6q 643 27 or or CC cord-006870-f5w6fw6q 643 28 microvascular microvascular JJ cord-006870-f5w6fw6q 643 29 ischemia ischemia NN cord-006870-f5w6fw6q 643 30 . . . cord-006870-f5w6fw6q 644 1 It -PRON- PRP cord-006870-f5w6fw6q 644 2 should should MD cord-006870-f5w6fw6q 644 3 be be VB cord-006870-f5w6fw6q 644 4 noted note VBN cord-006870-f5w6fw6q 644 5 that that IN cord-006870-f5w6fw6q 644 6 pulse pulse NN cord-006870-f5w6fw6q 644 7 oximetry oximetry NN cord-006870-f5w6fw6q 644 8 is be VBZ cord-006870-f5w6fw6q 644 9 not not RB cord-006870-f5w6fw6q 644 10 sensitive sensitive JJ cord-006870-f5w6fw6q 644 11 to to TO cord-006870-f5w6fw6q 644 12 detect detect VB cord-006870-f5w6fw6q 644 13 PaO2 PaO2 NNS cord-006870-f5w6fw6q 644 14 below below IN cord-006870-f5w6fw6q 644 15 this this DT cord-006870-f5w6fw6q 644 16 level level NN cord-006870-f5w6fw6q 644 17 . . . cord-006870-f5w6fw6q 645 1 Traumatic traumatic JJ cord-006870-f5w6fw6q 645 2 Brain Brain NNP cord-006870-f5w6fw6q 645 3 Injury Injury NNP cord-006870-f5w6fw6q 645 4 ( ( -LRB- cord-006870-f5w6fw6q 645 5 TBI TBI NNP cord-006870-f5w6fw6q 645 6 ) ) -RRB- cord-006870-f5w6fw6q 645 7 and and CC cord-006870-f5w6fw6q 645 8 stroke stroke NN cord-006870-f5w6fw6q 645 9 are be VBP cord-006870-f5w6fw6q 645 10 extremely extremely RB cord-006870-f5w6fw6q 645 11 common common JJ cord-006870-f5w6fw6q 645 12 causes cause NNS cord-006870-f5w6fw6q 645 13 of of IN cord-006870-f5w6fw6q 645 14 Acute Acute NNP cord-006870-f5w6fw6q 645 15 Brain Brain NNP cord-006870-f5w6fw6q 645 16 Injury Injury NNP cord-006870-f5w6fw6q 645 17 ( ( -LRB- cord-006870-f5w6fw6q 645 18 ABI ABI NNP cord-006870-f5w6fw6q 645 19 ) ) -RRB- cord-006870-f5w6fw6q 645 20 , , , cord-006870-f5w6fw6q 645 21 which which WDT cord-006870-f5w6fw6q 645 22 cause cause VBP cord-006870-f5w6fw6q 645 23 long long JJ cord-006870-f5w6fw6q 645 24 term term NN cord-006870-f5w6fw6q 645 25 disability disability NN cord-006870-f5w6fw6q 645 26 and and CC cord-006870-f5w6fw6q 645 27 permanent permanent JJ cord-006870-f5w6fw6q 645 28 neurological neurological JJ cord-006870-f5w6fw6q 645 29 impairment impairment NN cord-006870-f5w6fw6q 645 30 . . . cord-006870-f5w6fw6q 646 1 Coma coma NN cord-006870-f5w6fw6q 646 2 and and CC cord-006870-f5w6fw6q 646 3 stupor stupor NN cord-006870-f5w6fw6q 646 4 are be VBP cord-006870-f5w6fw6q 646 5 common common JJ cord-006870-f5w6fw6q 646 6 manifestations manifestation NNS cord-006870-f5w6fw6q 646 7 of of IN cord-006870-f5w6fw6q 646 8 ABI ABI NNP cord-006870-f5w6fw6q 646 9 , , , cord-006870-f5w6fw6q 646 10 due due IN cord-006870-f5w6fw6q 646 11 to to IN cord-006870-f5w6fw6q 646 12 interruptions interruption NNS cord-006870-f5w6fw6q 646 13 of of IN cord-006870-f5w6fw6q 646 14 the the DT cord-006870-f5w6fw6q 646 15 Ascending Ascending NNP cord-006870-f5w6fw6q 646 16 Reticular Reticular NNP cord-006870-f5w6fw6q 647 1 Activating activate VBG cord-006870-f5w6fw6q 647 2 System system NN cord-006870-f5w6fw6q 647 3 ( ( -LRB- cord-006870-f5w6fw6q 647 4 ARAS ARAS NNP cord-006870-f5w6fw6q 647 5 ) ) -RRB- cord-006870-f5w6fw6q 647 6 . . . cord-006870-f5w6fw6q 648 1 Neuro Neuro NNP cord-006870-f5w6fw6q 648 2 stimulants stimulant NNS cord-006870-f5w6fw6q 648 3 can can MD cord-006870-f5w6fw6q 648 4 improve improve VB cord-006870-f5w6fw6q 648 5 functioning function VBG cord-006870-f5w6fw6q 648 6 of of IN cord-006870-f5w6fw6q 648 7 the the DT cord-006870-f5w6fw6q 648 8 ARAS ara NNS cord-006870-f5w6fw6q 648 9 . . . cord-006870-f5w6fw6q 649 1 Despite despite IN cord-006870-f5w6fw6q 649 2 decades decade NNS cord-006870-f5w6fw6q 649 3 of of IN cord-006870-f5w6fw6q 649 4 research research NN cord-006870-f5w6fw6q 649 5 there there EX cord-006870-f5w6fw6q 649 6 is be VBZ cord-006870-f5w6fw6q 649 7 a a DT cord-006870-f5w6fw6q 649 8 paucity paucity NN cord-006870-f5w6fw6q 649 9 of of IN cord-006870-f5w6fw6q 649 10 prospective prospective JJ cord-006870-f5w6fw6q 649 11 high high JJ cord-006870-f5w6fw6q 649 12 - - HYPH cord-006870-f5w6fw6q 649 13 level level NN cord-006870-f5w6fw6q 649 14 evidence evidence NN cord-006870-f5w6fw6q 649 15 utilizing utilize VBG cord-006870-f5w6fw6q 649 16 neuro neuro NNP cord-006870-f5w6fw6q 649 17 stimulants stimulant NNS cord-006870-f5w6fw6q 649 18 to to TO cord-006870-f5w6fw6q 649 19 help help VB cord-006870-f5w6fw6q 649 20 with with IN cord-006870-f5w6fw6q 649 21 earlier early JJR cord-006870-f5w6fw6q 649 22 awakening awakening NN cord-006870-f5w6fw6q 649 23 from from IN cord-006870-f5w6fw6q 649 24 coma coma NN cord-006870-f5w6fw6q 649 25 and and CC cord-006870-f5w6fw6q 649 26 stupor stupor NN cord-006870-f5w6fw6q 649 27 in in IN cord-006870-f5w6fw6q 649 28 ABI ABI NNP cord-006870-f5w6fw6q 649 29 . . . cord-006870-f5w6fw6q 650 1 We -PRON- PRP cord-006870-f5w6fw6q 650 2 reviewed review VBD cord-006870-f5w6fw6q 650 3 the the DT cord-006870-f5w6fw6q 650 4 literature literature NN cord-006870-f5w6fw6q 650 5 using use VBG cord-006870-f5w6fw6q 650 6 the the DT cord-006870-f5w6fw6q 650 7 GRADE grade NN cord-006870-f5w6fw6q 650 8 level level NN cord-006870-f5w6fw6q 650 9 of of IN cord-006870-f5w6fw6q 650 10 evidence evidence NN cord-006870-f5w6fw6q 650 11 ( ( -LRB- cord-006870-f5w6fw6q 650 12 LOE LOE NNP cord-006870-f5w6fw6q 650 13 ) ) -RRB- cord-006870-f5w6fw6q 650 14 methodology methodology NN cord-006870-f5w6fw6q 650 15 . . . cord-006870-f5w6fw6q 651 1 We -PRON- PRP cord-006870-f5w6fw6q 651 2 performed perform VBD cord-006870-f5w6fw6q 651 3 a a DT cord-006870-f5w6fw6q 651 4 preliminary preliminary JJ cord-006870-f5w6fw6q 651 5 literature literature NN cord-006870-f5w6fw6q 651 6 search search NN cord-006870-f5w6fw6q 651 7 of of IN cord-006870-f5w6fw6q 651 8 the the DT cord-006870-f5w6fw6q 651 9 National National NNP cord-006870-f5w6fw6q 651 10 Library Library NNP cord-006870-f5w6fw6q 651 11 of of IN cord-006870-f5w6fw6q 651 12 Medicine Medicine NNP cord-006870-f5w6fw6q 651 13 ( ( -LRB- cord-006870-f5w6fw6q 651 14 NLM NLM NNP cord-006870-f5w6fw6q 651 15 ) ) -RRB- cord-006870-f5w6fw6q 651 16 using use VBG cord-006870-f5w6fw6q 651 17 search search NN cord-006870-f5w6fw6q 651 18 terms term NNS cord-006870-f5w6fw6q 651 19 ABI ABI NNP cord-006870-f5w6fw6q 651 20 and and CC cord-006870-f5w6fw6q 651 21 stimulants stimulant NNS cord-006870-f5w6fw6q 651 22 . . . cord-006870-f5w6fw6q 652 1 Within within IN cord-006870-f5w6fw6q 652 2 the the DT cord-006870-f5w6fw6q 652 3 literature literature NN cord-006870-f5w6fw6q 652 4 we -PRON- PRP cord-006870-f5w6fw6q 652 5 searched search VBD cord-006870-f5w6fw6q 652 6 for for IN cord-006870-f5w6fw6q 652 7 timing timing NN cord-006870-f5w6fw6q 652 8 of of IN cord-006870-f5w6fw6q 652 9 stimulant stimulant NN cord-006870-f5w6fw6q 652 10 use use NN cord-006870-f5w6fw6q 652 11 among among IN cord-006870-f5w6fw6q 652 12 ABI ABI NNP cord-006870-f5w6fw6q 652 13 studies study NNS cord-006870-f5w6fw6q 652 14 and and CC cord-006870-f5w6fw6q 652 15 included include VBD cord-006870-f5w6fw6q 652 16 all all DT cord-006870-f5w6fw6q 652 17 forms form NNS cord-006870-f5w6fw6q 652 18 of of IN cord-006870-f5w6fw6q 652 19 ABI ABI NNP cord-006870-f5w6fw6q 652 20 such such JJ cord-006870-f5w6fw6q 652 21 as as IN cord-006870-f5w6fw6q 652 22 TBI TBI NNP cord-006870-f5w6fw6q 652 23 , , , cord-006870-f5w6fw6q 652 24 stroke stroke NN cord-006870-f5w6fw6q 652 25 , , , cord-006870-f5w6fw6q 652 26 and and CC cord-006870-f5w6fw6q 652 27 anoxic anoxic JJ cord-006870-f5w6fw6q 652 28 injury injury NN cord-006870-f5w6fw6q 652 29 . . . cord-006870-f5w6fw6q 653 1 We -PRON- PRP cord-006870-f5w6fw6q 653 2 retrieved retrieve VBD cord-006870-f5w6fw6q 653 3 508 508 CD cord-006870-f5w6fw6q 653 4 total total JJ cord-006870-f5w6fw6q 653 5 results result NNS cord-006870-f5w6fw6q 653 6 , , , cord-006870-f5w6fw6q 653 7 of of IN cord-006870-f5w6fw6q 653 8 which which WDT cord-006870-f5w6fw6q 653 9 we -PRON- PRP cord-006870-f5w6fw6q 653 10 excluded exclude VBD cord-006870-f5w6fw6q 653 11 474 474 CD cord-006870-f5w6fw6q 653 12 since since IN cord-006870-f5w6fw6q 653 13 they -PRON- PRP cord-006870-f5w6fw6q 653 14 did do VBD cord-006870-f5w6fw6q 653 15 not not RB cord-006870-f5w6fw6q 653 16 meet meet VB cord-006870-f5w6fw6q 653 17 GRADE grade NN cord-006870-f5w6fw6q 653 18 high high JJ cord-006870-f5w6fw6q 653 19 LOE LOE NNP cord-006870-f5w6fw6q 653 20 criteria criterion NNS cord-006870-f5w6fw6q 653 21 or or CC cord-006870-f5w6fw6q 653 22 were be VBD cord-006870-f5w6fw6q 653 23 " " `` cord-006870-f5w6fw6q 653 24 n n CC cord-006870-f5w6fw6q 653 25 of of IN cord-006870-f5w6fw6q 653 26 1 1 CD cord-006870-f5w6fw6q 653 27 " " '' cord-006870-f5w6fw6q 653 28 studies study NNS cord-006870-f5w6fw6q 653 29 or or CC cord-006870-f5w6fw6q 653 30 aggregates aggregate NNS cord-006870-f5w6fw6q 653 31 . . . cord-006870-f5w6fw6q 654 1 Only only RB cord-006870-f5w6fw6q 654 2 34 34 CD cord-006870-f5w6fw6q 654 3 high high JJ cord-006870-f5w6fw6q 654 4 LOE LOE NNP cord-006870-f5w6fw6q 654 5 randomized randomized JJ cord-006870-f5w6fw6q 654 6 studies study NNS cord-006870-f5w6fw6q 654 7 or or CC cord-006870-f5w6fw6q 654 8 meta meta NNP cord-006870-f5w6fw6q 654 9 - - HYPH cord-006870-f5w6fw6q 654 10 analyses analysis NNS cord-006870-f5w6fw6q 654 11 were be VBD cord-006870-f5w6fw6q 654 12 found find VBN cord-006870-f5w6fw6q 654 13 . . . cord-006870-f5w6fw6q 655 1 Among among IN cord-006870-f5w6fw6q 655 2 these these DT cord-006870-f5w6fw6q 655 3 various various JJ cord-006870-f5w6fw6q 655 4 stimulants stimulant NNS cord-006870-f5w6fw6q 655 5 were be VBD cord-006870-f5w6fw6q 655 6 investigated investigate VBN cord-006870-f5w6fw6q 655 7 including include VBG cord-006870-f5w6fw6q 655 8 methamphetamines methamphetamine NNS cord-006870-f5w6fw6q 655 9 such such JJ cord-006870-f5w6fw6q 655 10 as as IN cord-006870-f5w6fw6q 655 11 methylphenidate methylphenidate NN cord-006870-f5w6fw6q 655 12 and and CC cord-006870-f5w6fw6q 655 13 lisdexamfetamine lisdexamfetamine NN cord-006870-f5w6fw6q 655 14 , , , cord-006870-f5w6fw6q 655 15 caffeine caffeine NN cord-006870-f5w6fw6q 655 16 , , , cord-006870-f5w6fw6q 655 17 armodafinil armodafinil NN cord-006870-f5w6fw6q 655 18 , , , cord-006870-f5w6fw6q 655 19 galantamine galantamine NNP cord-006870-f5w6fw6q 655 20 , , , cord-006870-f5w6fw6q 655 21 and and CC cord-006870-f5w6fw6q 655 22 amantadine amantadine NNP cord-006870-f5w6fw6q 655 23 . . . cord-006870-f5w6fw6q 656 1 Methylphenidate Methylphenidate NNP cord-006870-f5w6fw6q 656 2 had have VBD cord-006870-f5w6fw6q 656 3 10 10 CD cord-006870-f5w6fw6q 656 4 randomized randomized JJ cord-006870-f5w6fw6q 656 5 trials trial NNS cord-006870-f5w6fw6q 656 6 and and CC cord-006870-f5w6fw6q 656 7 a a DT cord-006870-f5w6fw6q 656 8 meta meta JJ cord-006870-f5w6fw6q 656 9 - - HYPH cord-006870-f5w6fw6q 656 10 analysis analysis NN cord-006870-f5w6fw6q 656 11 in in IN cord-006870-f5w6fw6q 656 12 subacute subacute JJ cord-006870-f5w6fw6q 656 13 TBI TBI NNP cord-006870-f5w6fw6q 656 14 but but CC cord-006870-f5w6fw6q 656 15 reported report VBD cord-006870-f5w6fw6q 656 16 only only JJ cord-006870-f5w6fw6q 656 17 attention attention NN cord-006870-f5w6fw6q 656 18 as as IN cord-006870-f5w6fw6q 656 19 a a DT cord-006870-f5w6fw6q 656 20 main main JJ cord-006870-f5w6fw6q 656 21 outcome outcome NN cord-006870-f5w6fw6q 656 22 . . . cord-006870-f5w6fw6q 657 1 We -PRON- PRP cord-006870-f5w6fw6q 657 2 were be VBD cord-006870-f5w6fw6q 657 3 unable unable JJ cord-006870-f5w6fw6q 657 4 to to TO cord-006870-f5w6fw6q 657 5 draw draw VB cord-006870-f5w6fw6q 657 6 broad broad JJ cord-006870-f5w6fw6q 657 7 - - HYPH cord-006870-f5w6fw6q 657 8 level level NN cord-006870-f5w6fw6q 657 9 recommendations recommendation NNS cord-006870-f5w6fw6q 657 10 about about IN cord-006870-f5w6fw6q 657 11 optimal optimal JJ cord-006870-f5w6fw6q 657 12 timing timing NN cord-006870-f5w6fw6q 657 13 , , , cord-006870-f5w6fw6q 657 14 best good JJS cord-006870-f5w6fw6q 657 15 stimulant stimulant NN cord-006870-f5w6fw6q 657 16 , , , cord-006870-f5w6fw6q 657 17 and and CC cord-006870-f5w6fw6q 657 18 patient patient JJ cord-006870-f5w6fw6q 657 19 centered center VBN cord-006870-f5w6fw6q 657 20 outcomes outcome NNS cord-006870-f5w6fw6q 657 21 from from IN cord-006870-f5w6fw6q 657 22 this this DT cord-006870-f5w6fw6q 657 23 data datum NNS cord-006870-f5w6fw6q 657 24 . . . cord-006870-f5w6fw6q 658 1 There there EX cord-006870-f5w6fw6q 658 2 is be VBZ cord-006870-f5w6fw6q 658 3 insufficient insufficient JJ cord-006870-f5w6fw6q 658 4 data datum NNS cord-006870-f5w6fw6q 658 5 to to TO cord-006870-f5w6fw6q 658 6 recommend recommend VB cord-006870-f5w6fw6q 658 7 optimal optimal JJ cord-006870-f5w6fw6q 658 8 stimulant stimulant NN cord-006870-f5w6fw6q 658 9 , , , cord-006870-f5w6fw6q 658 10 timing timing NN cord-006870-f5w6fw6q 658 11 , , , cord-006870-f5w6fw6q 658 12 and and CC cord-006870-f5w6fw6q 658 13 dosing dose VBG cord-006870-f5w6fw6q 658 14 among among IN cord-006870-f5w6fw6q 658 15 heterogeneous heterogeneous JJ cord-006870-f5w6fw6q 658 16 ABI ABI NNP cord-006870-f5w6fw6q 658 17 disease disease NN cord-006870-f5w6fw6q 658 18 models model NNS cord-006870-f5w6fw6q 658 19 . . . cord-006870-f5w6fw6q 659 1 We -PRON- PRP cord-006870-f5w6fw6q 659 2 propose propose VBP cord-006870-f5w6fw6q 659 3 conducting conduct VBG cord-006870-f5w6fw6q 659 4 future future JJ cord-006870-f5w6fw6q 659 5 homogenous homogenous JJ cord-006870-f5w6fw6q 659 6 ABI ABI NNP cord-006870-f5w6fw6q 659 7 neuro neuro NNP cord-006870-f5w6fw6q 659 8 stimulant stimulant NN cord-006870-f5w6fw6q 659 9 trials trial NNS cord-006870-f5w6fw6q 659 10 in in IN cord-006870-f5w6fw6q 659 11 for for IN cord-006870-f5w6fw6q 659 12 safety safety NN cord-006870-f5w6fw6q 659 13 , , , cord-006870-f5w6fw6q 659 14 tolerability tolerability NN cord-006870-f5w6fw6q 659 15 , , , cord-006870-f5w6fw6q 659 16 dose dose NN cord-006870-f5w6fw6q 659 17 - - HYPH cord-006870-f5w6fw6q 659 18 finding find VBG cord-006870-f5w6fw6q 659 19 , , , cord-006870-f5w6fw6q 659 20 optimal optimal JJ cord-006870-f5w6fw6q 659 21 timing timing NN cord-006870-f5w6fw6q 659 22 , , , cord-006870-f5w6fw6q 659 23 and and CC cord-006870-f5w6fw6q 659 24 outcomes outcome NNS cord-006870-f5w6fw6q 659 25 based base VBN cord-006870-f5w6fw6q 659 26 efficacy efficacy NN cord-006870-f5w6fw6q 659 27 . . . cord-006870-f5w6fw6q 660 1 Neuro Neuro NNP cord-006870-f5w6fw6q 660 2 stimulants stimulant NNS cord-006870-f5w6fw6q 660 3 could could MD cord-006870-f5w6fw6q 660 4 play play VB cord-006870-f5w6fw6q 660 5 a a DT cord-006870-f5w6fw6q 660 6 role role NN cord-006870-f5w6fw6q 660 7 in in IN cord-006870-f5w6fw6q 660 8 earlier early JJR cord-006870-f5w6fw6q 660 9 awakening awakening NN cord-006870-f5w6fw6q 660 10 and and CC cord-006870-f5w6fw6q 660 11 extubation extubation NN cord-006870-f5w6fw6q 660 12 in in IN cord-006870-f5w6fw6q 660 13 ABI ABI NNP cord-006870-f5w6fw6q 660 14 which which WDT cord-006870-f5w6fw6q 660 15 could could MD cord-006870-f5w6fw6q 660 16 improve improve VB cord-006870-f5w6fw6q 660 17 outcomes outcome NNS cord-006870-f5w6fw6q 660 18 similar similar JJ cord-006870-f5w6fw6q 660 19 to to IN cord-006870-f5w6fw6q 660 20 sedation sedation NN cord-006870-f5w6fw6q 660 21 / / SYM cord-006870-f5w6fw6q 660 22 vacation vacation NN cord-006870-f5w6fw6q 660 23 bundles bundle NNS cord-006870-f5w6fw6q 660 24 in in IN cord-006870-f5w6fw6q 660 25 ICU ICU NNP cord-006870-f5w6fw6q 660 26 's 's POS cord-006870-f5w6fw6q 660 27 currently currently RB cord-006870-f5w6fw6q 660 28 if if IN cord-006870-f5w6fw6q 660 29 studied study VBN cord-006870-f5w6fw6q 660 30 adequately adequately RB cord-006870-f5w6fw6q 660 31 . . . cord-006870-f5w6fw6q 661 1 TBI TBI NNP cord-006870-f5w6fw6q 661 2 remains remain VBZ cord-006870-f5w6fw6q 661 3 the the DT cord-006870-f5w6fw6q 661 4 leading leading JJ cord-006870-f5w6fw6q 661 5 cause cause NN cord-006870-f5w6fw6q 661 6 of of IN cord-006870-f5w6fw6q 661 7 death death NN cord-006870-f5w6fw6q 661 8 and and CC cord-006870-f5w6fw6q 661 9 disability disability NN cord-006870-f5w6fw6q 661 10 in in IN cord-006870-f5w6fw6q 661 11 young young JJ cord-006870-f5w6fw6q 661 12 adults adult NNS cord-006870-f5w6fw6q 661 13 in in IN cord-006870-f5w6fw6q 661 14 the the DT cord-006870-f5w6fw6q 661 15 US US NNP cord-006870-f5w6fw6q 661 16 and and CC cord-006870-f5w6fw6q 661 17 Europe Europe NNP cord-006870-f5w6fw6q 661 18 . . . cord-006870-f5w6fw6q 662 1 Thus thus RB cord-006870-f5w6fw6q 662 2 far far RB cord-006870-f5w6fw6q 662 3 , , , cord-006870-f5w6fw6q 662 4 pharmacological pharmacological JJ cord-006870-f5w6fw6q 662 5 and and CC cord-006870-f5w6fw6q 662 6 non non JJ cord-006870-f5w6fw6q 662 7 - - JJ cord-006870-f5w6fw6q 662 8 pharmacological pharmacological JJ cord-006870-f5w6fw6q 662 9 intervention intervention NN cord-006870-f5w6fw6q 662 10 studies study NNS cord-006870-f5w6fw6q 662 11 did do VBD cord-006870-f5w6fw6q 662 12 not not RB cord-006870-f5w6fw6q 662 13 confirm confirm VB cord-006870-f5w6fw6q 662 14 benefits benefit NNS cord-006870-f5w6fw6q 662 15 on on IN cord-006870-f5w6fw6q 662 16 functional functional JJ cord-006870-f5w6fw6q 662 17 outcomes outcome NNS cord-006870-f5w6fw6q 662 18 . . . cord-006870-f5w6fw6q 663 1 The the DT cord-006870-f5w6fw6q 663 2 inducible inducible JJ cord-006870-f5w6fw6q 663 3 enzyme enzyme NN cord-006870-f5w6fw6q 663 4 Nitric nitric NN cord-006870-f5w6fw6q 663 5 Oxide oxide NN cord-006870-f5w6fw6q 663 6 Synthase Synthase NNP cord-006870-f5w6fw6q 663 7 ( ( -LRB- cord-006870-f5w6fw6q 663 8 iNOS inos NN cord-006870-f5w6fw6q 663 9 ) ) -RRB- cord-006870-f5w6fw6q 663 10 is be VBZ cord-006870-f5w6fw6q 663 11 upregulated upregulate VBN cord-006870-f5w6fw6q 663 12 in in IN cord-006870-f5w6fw6q 663 13 response response NN cord-006870-f5w6fw6q 663 14 to to IN cord-006870-f5w6fw6q 663 15 brain brain NN cord-006870-f5w6fw6q 663 16 injury injury NN cord-006870-f5w6fw6q 663 17 , , , cord-006870-f5w6fw6q 663 18 causing cause VBG cord-006870-f5w6fw6q 663 19 excessive excessive JJ cord-006870-f5w6fw6q 663 20 production production NN cord-006870-f5w6fw6q 663 21 of of IN cord-006870-f5w6fw6q 663 22 NO no NN cord-006870-f5w6fw6q 663 23 , , , cord-006870-f5w6fw6q 663 24 a a DT cord-006870-f5w6fw6q 663 25 key key JJ cord-006870-f5w6fw6q 663 26 driver driver NN cord-006870-f5w6fw6q 663 27 of of IN cord-006870-f5w6fw6q 663 28 secondary secondary JJ cord-006870-f5w6fw6q 663 29 injury injury NN cord-006870-f5w6fw6q 663 30 after after IN cord-006870-f5w6fw6q 663 31 TBI TBI NNP cord-006870-f5w6fw6q 663 32 . . . cord-006870-f5w6fw6q 664 1 The the DT cord-006870-f5w6fw6q 664 2 antipterin antipterin NN cord-006870-f5w6fw6q 664 3 VAS203 VAS203 NNP cord-006870-f5w6fw6q 664 4 is be VBZ cord-006870-f5w6fw6q 664 5 a a DT cord-006870-f5w6fw6q 664 6 structural structural JJ cord-006870-f5w6fw6q 664 7 analogue analogue NN cord-006870-f5w6fw6q 664 8 of of IN cord-006870-f5w6fw6q 664 9 the the DT cord-006870-f5w6fw6q 664 10 endogenous endogenous JJ cord-006870-f5w6fw6q 664 11 NOS NOS NNP cord-006870-f5w6fw6q 664 12 cofactor cofactor NN cord-006870-f5w6fw6q 664 13 and and CC cord-006870-f5w6fw6q 664 14 a a DT cord-006870-f5w6fw6q 664 15 potent potent JJ cord-006870-f5w6fw6q 664 16 in in IN cord-006870-f5w6fw6q 664 17 - - HYPH cord-006870-f5w6fw6q 664 18 vivo vivo NN cord-006870-f5w6fw6q 664 19 selective selective JJ cord-006870-f5w6fw6q 664 20 inhibitor inhibitor NN cord-006870-f5w6fw6q 664 21 of of IN cord-006870-f5w6fw6q 664 22 iNOS inos NN cord-006870-f5w6fw6q 664 23 . . . cord-006870-f5w6fw6q 665 1 A a DT cord-006870-f5w6fw6q 665 2 randomized randomized JJ cord-006870-f5w6fw6q 665 3 , , , cord-006870-f5w6fw6q 665 4 placebo placebo NN cord-006870-f5w6fw6q 665 5 - - HYPH cord-006870-f5w6fw6q 665 6 controlled control VBN cord-006870-f5w6fw6q 665 7 Phase Phase NNP cord-006870-f5w6fw6q 665 8 2 2 CD cord-006870-f5w6fw6q 665 9 study study NN cord-006870-f5w6fw6q 665 10 examined examine VBD cord-006870-f5w6fw6q 665 11 3 3 CD cord-006870-f5w6fw6q 665 12 dose dose NN cord-006870-f5w6fw6q 665 13 levels level NNS cord-006870-f5w6fw6q 665 14 of of IN cord-006870-f5w6fw6q 665 15 VAS203 vas203 NN cord-006870-f5w6fw6q 665 16 in in IN cord-006870-f5w6fw6q 665 17 32 32 CD cord-006870-f5w6fw6q 665 18 patients patient NNS cord-006870-f5w6fw6q 665 19 with with IN cord-006870-f5w6fw6q 665 20 acute acute JJ cord-006870-f5w6fw6q 665 21 moderate moderate JJ cord-006870-f5w6fw6q 665 22 or or CC cord-006870-f5w6fw6q 665 23 severe severe JJ cord-006870-f5w6fw6q 665 24 TBI tbi NN cord-006870-f5w6fw6q 665 25 . . . cord-006870-f5w6fw6q 666 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 666 2 microdialysis microdialysis NN cord-006870-f5w6fw6q 666 3 showed show VBD cord-006870-f5w6fw6q 666 4 pharmacologically pharmacologically RB cord-006870-f5w6fw6q 666 5 relevant relevant JJ cord-006870-f5w6fw6q 666 6 drug drug NN cord-006870-f5w6fw6q 666 7 concentrations concentration NNS cord-006870-f5w6fw6q 666 8 close close JJ cord-006870-f5w6fw6q 666 9 to to IN cord-006870-f5w6fw6q 666 10 the the DT cord-006870-f5w6fw6q 666 11 injury injury NN cord-006870-f5w6fw6q 666 12 and and CC cord-006870-f5w6fw6q 666 13 a a DT cord-006870-f5w6fw6q 666 14 tendency tendency NN cord-006870-f5w6fw6q 666 15 for for IN cord-006870-f5w6fw6q 666 16 VAS203 VAS203 NNP cord-006870-f5w6fw6q 666 17 to to TO cord-006870-f5w6fw6q 666 18 increase increase VB cord-006870-f5w6fw6q 666 19 the the DT cord-006870-f5w6fw6q 666 20 arginine arginine NN cord-006870-f5w6fw6q 666 21 / / SYM cord-006870-f5w6fw6q 666 22 citrulline citrulline NN cord-006870-f5w6fw6q 666 23 ratio ratio NN cord-006870-f5w6fw6q 666 24 , , , cord-006870-f5w6fw6q 666 25 an an DT cord-006870-f5w6fw6q 666 26 indirect indirect JJ cord-006870-f5w6fw6q 666 27 marker marker NN cord-006870-f5w6fw6q 666 28 of of IN cord-006870-f5w6fw6q 666 29 NOS NOS NNP cord-006870-f5w6fw6q 666 30 inhibition inhibition NN cord-006870-f5w6fw6q 666 31 ( ( -LRB- cord-006870-f5w6fw6q 666 32 Stover Stover NNP cord-006870-f5w6fw6q 666 33 et et FW cord-006870-f5w6fw6q 666 34 al al NNP cord-006870-f5w6fw6q 666 35 . . . cord-006870-f5w6fw6q 667 1 , , , cord-006870-f5w6fw6q 667 2 J J NNP cord-006870-f5w6fw6q 667 3 Neurotrauma Neurotrauma NNP cord-006870-f5w6fw6q 667 4 2014 2014 CD cord-006870-f5w6fw6q 667 5 ) ) -RRB- cord-006870-f5w6fw6q 667 6 . . . cord-006870-f5w6fw6q 668 1 VAS203 VAS203 NNP cord-006870-f5w6fw6q 668 2 conferred confer VBD cord-006870-f5w6fw6q 668 3 a a DT cord-006870-f5w6fw6q 668 4 significant significant JJ cord-006870-f5w6fw6q 668 5 benefit benefit NN cord-006870-f5w6fw6q 668 6 on on IN cord-006870-f5w6fw6q 668 7 the the DT cord-006870-f5w6fw6q 668 8 extended extended JJ cord-006870-f5w6fw6q 668 9 Glasgow Glasgow NNP cord-006870-f5w6fw6q 668 10 Outcome Outcome NNP cord-006870-f5w6fw6q 668 11 Scale Scale NNP cord-006870-f5w6fw6q 668 12 Interview interview NN cord-006870-f5w6fw6q 668 13 ( ( -LRB- cord-006870-f5w6fw6q 668 14 eGOS ego NNS cord-006870-f5w6fw6q 668 15 - - : cord-006870-f5w6fw6q 668 16 I i NN cord-006870-f5w6fw6q 668 17 ) ) -RRB- cord-006870-f5w6fw6q 668 18 at at IN cord-006870-f5w6fw6q 668 19 6 6 CD cord-006870-f5w6fw6q 668 20 and and CC cord-006870-f5w6fw6q 668 21 12 12 CD cord-006870-f5w6fw6q 668 22 months month NNS cord-006870-f5w6fw6q 668 23 after after IN cord-006870-f5w6fw6q 668 24 injury injury NN cord-006870-f5w6fw6q 668 25 . . . cord-006870-f5w6fw6q 669 1 No no DT cord-006870-f5w6fw6q 669 2 changes change NNS cord-006870-f5w6fw6q 669 3 in in IN cord-006870-f5w6fw6q 669 4 systemic systemic JJ cord-006870-f5w6fw6q 669 5 blood blood NN cord-006870-f5w6fw6q 669 6 pressure pressure NN cord-006870-f5w6fw6q 669 7 or or CC cord-006870-f5w6fw6q 669 8 partial partial JJ cord-006870-f5w6fw6q 669 9 brain brain NN cord-006870-f5w6fw6q 669 10 oxygen oxygen NN cord-006870-f5w6fw6q 669 11 pressure pressure NN cord-006870-f5w6fw6q 669 12 were be VBD cord-006870-f5w6fw6q 669 13 noted note VBN cord-006870-f5w6fw6q 669 14 . . . cord-006870-f5w6fw6q 670 1 A a DT cord-006870-f5w6fw6q 670 2 recent recent JJ cord-006870-f5w6fw6q 670 3 pharmacokinetics pharmacokinetic NNS cord-006870-f5w6fw6q 670 4 and and CC cord-006870-f5w6fw6q 670 5 pharmacodynamics pharmacodynamic NNS cord-006870-f5w6fw6q 670 6 study study VBP cord-006870-f5w6fw6q 670 7 further further RB cord-006870-f5w6fw6q 670 8 corroborated corroborate VBD cord-006870-f5w6fw6q 670 9 the the DT cord-006870-f5w6fw6q 670 10 selective selective JJ cord-006870-f5w6fw6q 670 11 iNOS inos JJ cord-006870-f5w6fw6q 670 12 inhibition inhibition NN cord-006870-f5w6fw6q 670 13 by by IN cord-006870-f5w6fw6q 670 14 VAS203 VAS203 NNP cord-006870-f5w6fw6q 670 15 . . . cord-006870-f5w6fw6q 671 1 The the DT cord-006870-f5w6fw6q 671 2 confirmatory confirmatory JJ cord-006870-f5w6fw6q 671 3 NOSTRA NOSTRA NNP cord-006870-f5w6fw6q 671 4 Phase Phase NNP cord-006870-f5w6fw6q 671 5 3 3 CD cord-006870-f5w6fw6q 671 6 trial trial NN cord-006870-f5w6fw6q 671 7 ( ( -LRB- cord-006870-f5w6fw6q 671 8 EudraCT eudract VB cord-006870-f5w6fw6q 671 9 no no NN cord-006870-f5w6fw6q 671 10 . . NN cord-006870-f5w6fw6q 671 11 2013 2013 CD cord-006870-f5w6fw6q 671 12 - - HYPH cord-006870-f5w6fw6q 671 13 003368 003368 CD cord-006870-f5w6fw6q 671 14 - - HYPH cord-006870-f5w6fw6q 671 15 29 29 CD cord-006870-f5w6fw6q 671 16 ; ; : cord-006870-f5w6fw6q 671 17 ClinicalTrials.gov ClinicalTrials.gov NNP cord-006870-f5w6fw6q 671 18 identifier identifier NN cord-006870-f5w6fw6q 671 19 NCT02794168 NCT02794168 NNP cord-006870-f5w6fw6q 671 20 ) ) -RRB- cord-006870-f5w6fw6q 671 21 was be VBD cord-006870-f5w6fw6q 671 22 initiated initiate VBN cord-006870-f5w6fw6q 671 23 in in IN cord-006870-f5w6fw6q 671 24 2016 2016 CD cord-006870-f5w6fw6q 671 25 . . . cord-006870-f5w6fw6q 672 1 Adult adult NN cord-006870-f5w6fw6q 672 2 patients patient NNS cord-006870-f5w6fw6q 672 3 with with IN cord-006870-f5w6fw6q 672 4 a a DT cord-006870-f5w6fw6q 672 5 nonrequiring nonrequire VBG cord-006870-f5w6fw6q 672 6 intracranial intracranial JJ cord-006870-f5w6fw6q 672 7 pressure pressure NN cord-006870-f5w6fw6q 672 8 monitoring monitoring NN cord-006870-f5w6fw6q 672 9 , , , cord-006870-f5w6fw6q 672 10 are be VBP cord-006870-f5w6fw6q 672 11 randomized randomize VBN cord-006870-f5w6fw6q 672 12 1:1 1:1 CD cord-006870-f5w6fw6q 672 13 to to IN cord-006870-f5w6fw6q 672 14 VAS203 vas203 NN cord-006870-f5w6fw6q 672 15 or or CC cord-006870-f5w6fw6q 672 16 placebo placebo NN cord-006870-f5w6fw6q 672 17 , , , cord-006870-f5w6fw6q 672 18 administered administer VBN cord-006870-f5w6fw6q 672 19 in in IN cord-006870-f5w6fw6q 672 20 addition addition NN cord-006870-f5w6fw6q 672 21 to to IN cord-006870-f5w6fw6q 672 22 standard standard NN cord-006870-f5w6fw6q 672 23 of of IN cord-006870-f5w6fw6q 672 24 care care NN cord-006870-f5w6fw6q 672 25 , , , cord-006870-f5w6fw6q 672 26 as as IN cord-006870-f5w6fw6q 672 27 intravenous intravenous JJ cord-006870-f5w6fw6q 672 28 continuous continuous JJ cord-006870-f5w6fw6q 672 29 infusion infusion NN cord-006870-f5w6fw6q 672 30 for for IN cord-006870-f5w6fw6q 672 31 48 48 CD cord-006870-f5w6fw6q 672 32 hours hour NNS cord-006870-f5w6fw6q 672 33 , , , cord-006870-f5w6fw6q 672 34 starting start VBG cord-006870-f5w6fw6q 672 35 between between IN cord-006870-f5w6fw6q 672 36 6 6 CD cord-006870-f5w6fw6q 672 37 and and CC cord-006870-f5w6fw6q 672 38 18 18 CD cord-006870-f5w6fw6q 672 39 hours hour NNS cord-006870-f5w6fw6q 672 40 post post NN cord-006870-f5w6fw6q 672 41 TBI TBI NNP cord-006870-f5w6fw6q 672 42 . . . cord-006870-f5w6fw6q 673 1 The the DT cord-006870-f5w6fw6q 673 2 primary primary JJ cord-006870-f5w6fw6q 673 3 efficacy efficacy NN cord-006870-f5w6fw6q 673 4 endpoint endpoint NN cord-006870-f5w6fw6q 673 5 is be VBZ cord-006870-f5w6fw6q 674 1 eGOS ego NNS cord-006870-f5w6fw6q 674 2 - - : cord-006870-f5w6fw6q 674 3 I -PRON- PRP cord-006870-f5w6fw6q 674 4 at at IN cord-006870-f5w6fw6q 674 5 6 6 CD cord-006870-f5w6fw6q 674 6 months month NNS cord-006870-f5w6fw6q 674 7 post post NN cord-006870-f5w6fw6q 674 8 injury injury NN cord-006870-f5w6fw6q 674 9 . . . cord-006870-f5w6fw6q 675 1 Additional additional JJ cord-006870-f5w6fw6q 675 2 endpoints endpoint NNS cord-006870-f5w6fw6q 675 3 include include VBP cord-006870-f5w6fw6q 675 4 the the DT cord-006870-f5w6fw6q 675 5 daily daily JJ cord-006870-f5w6fw6q 675 6 therapy therapy NN cord-006870-f5w6fw6q 675 7 intensity intensity NN cord-006870-f5w6fw6q 675 8 level level NN cord-006870-f5w6fw6q 675 9 and and CC cord-006870-f5w6fw6q 675 10 TBI tbi NN cord-006870-f5w6fw6q 675 11 - - HYPH cord-006870-f5w6fw6q 675 12 specific specific JJ cord-006870-f5w6fw6q 675 13 quality quality NN cord-006870-f5w6fw6q 675 14 of of IN cord-006870-f5w6fw6q 675 15 life life NN cord-006870-f5w6fw6q 675 16 measures measure NNS cord-006870-f5w6fw6q 675 17 . . . cord-006870-f5w6fw6q 676 1 Continuous continuous JJ cord-006870-f5w6fw6q 676 2 safety safety NN cord-006870-f5w6fw6q 676 3 monitoring monitoring NN cord-006870-f5w6fw6q 676 4 is be VBZ cord-006870-f5w6fw6q 676 5 performed perform VBN cord-006870-f5w6fw6q 676 6 by by IN cord-006870-f5w6fw6q 676 7 an an DT cord-006870-f5w6fw6q 676 8 independent independent JJ cord-006870-f5w6fw6q 676 9 committee committee NN cord-006870-f5w6fw6q 676 10 . . . cord-006870-f5w6fw6q 677 1 NOSTRA NOSTRA NNP cord-006870-f5w6fw6q 677 2 III III NNP cord-006870-f5w6fw6q 677 3 , , , cord-006870-f5w6fw6q 677 4 the the DT cord-006870-f5w6fw6q 677 5 only only JJ cord-006870-f5w6fw6q 677 6 ongoing ongoing JJ cord-006870-f5w6fw6q 677 7 registration registration NN cord-006870-f5w6fw6q 677 8 study study NN cord-006870-f5w6fw6q 677 9 in in IN cord-006870-f5w6fw6q 677 10 acute acute JJ cord-006870-f5w6fw6q 677 11 moderate moderate JJ cord-006870-f5w6fw6q 677 12 and and CC cord-006870-f5w6fw6q 677 13 severe severe JJ cord-006870-f5w6fw6q 677 14 TBI TBI NNP cord-006870-f5w6fw6q 677 15 , , , cord-006870-f5w6fw6q 677 16 is be VBZ cord-006870-f5w6fw6q 677 17 sponsored sponsor VBN cord-006870-f5w6fw6q 677 18 by by IN cord-006870-f5w6fw6q 677 19 vasopharm vasopharm NNP cord-006870-f5w6fw6q 677 20 GmbH GmbH NNP cord-006870-f5w6fw6q 677 21 , , , cord-006870-f5w6fw6q 677 22 and and CC cord-006870-f5w6fw6q 677 23 plans plan VBZ cord-006870-f5w6fw6q 677 24 to to TO cord-006870-f5w6fw6q 677 25 recruit recruit VB cord-006870-f5w6fw6q 677 26 232 232 CD cord-006870-f5w6fw6q 677 27 patients patient NNS cord-006870-f5w6fw6q 677 28 by by IN cord-006870-f5w6fw6q 677 29 Q3 Q3 NNP cord-006870-f5w6fw6q 677 30 2018 2018 CD cord-006870-f5w6fw6q 677 31 . . . cord-006870-f5w6fw6q 678 1 A a DT cord-006870-f5w6fw6q 678 2 Glasgow Glasgow NNP cord-006870-f5w6fw6q 678 3 Coma Coma NNP cord-006870-f5w6fw6q 678 4 Scale Scale NNP cord-006870-f5w6fw6q 678 5 ( ( -LRB- cord-006870-f5w6fw6q 678 6 GCS GCS NNP cord-006870-f5w6fw6q 678 7 ) ) -RRB- cord-006870-f5w6fw6q 678 8 score score NN cord-006870-f5w6fw6q 678 9 of of IN cord-006870-f5w6fw6q 678 10 3 3 CD cord-006870-f5w6fw6q 678 11 on on IN cord-006870-f5w6fw6q 678 12 presentation presentation NN cord-006870-f5w6fw6q 678 13 in in IN cord-006870-f5w6fw6q 678 14 patients patient NNS cord-006870-f5w6fw6q 678 15 with with IN cord-006870-f5w6fw6q 678 16 traumatic traumatic JJ cord-006870-f5w6fw6q 678 17 brain brain NN cord-006870-f5w6fw6q 678 18 injury injury NN cord-006870-f5w6fw6q 678 19 ( ( -LRB- cord-006870-f5w6fw6q 678 20 TBI TBI NNP cord-006870-f5w6fw6q 678 21 ) ) -RRB- cord-006870-f5w6fw6q 678 22 portends portend VBZ cord-006870-f5w6fw6q 678 23 a a DT cord-006870-f5w6fw6q 678 24 poor poor JJ cord-006870-f5w6fw6q 678 25 prognosis prognosis NN cord-006870-f5w6fw6q 678 26 . . . cord-006870-f5w6fw6q 679 1 Consequently consequently RB cord-006870-f5w6fw6q 679 2 , , , cord-006870-f5w6fw6q 679 3 there there EX cord-006870-f5w6fw6q 679 4 is be VBZ cord-006870-f5w6fw6q 679 5 often often RB cord-006870-f5w6fw6q 679 6 a a DT cord-006870-f5w6fw6q 679 7 tendency tendency NN cord-006870-f5w6fw6q 679 8 to to TO cord-006870-f5w6fw6q 679 9 treat treat VB cord-006870-f5w6fw6q 679 10 these these DT cord-006870-f5w6fw6q 679 11 patients patient NNS cord-006870-f5w6fw6q 679 12 less less RBR cord-006870-f5w6fw6q 679 13 aggressively aggressively RB cord-006870-f5w6fw6q 679 14 because because IN cord-006870-f5w6fw6q 679 15 of of IN cord-006870-f5w6fw6q 679 16 low low JJ cord-006870-f5w6fw6q 679 17 expectations expectation NNS cord-006870-f5w6fw6q 679 18 for for IN cord-006870-f5w6fw6q 679 19 a a DT cord-006870-f5w6fw6q 679 20 good good JJ cord-006870-f5w6fw6q 679 21 outcome outcome NN cord-006870-f5w6fw6q 679 22 . . . cord-006870-f5w6fw6q 680 1 We -PRON- PRP cord-006870-f5w6fw6q 680 2 performed perform VBD cord-006870-f5w6fw6q 680 3 a a DT cord-006870-f5w6fw6q 680 4 retrospective retrospective JJ cord-006870-f5w6fw6q 680 5 review review NN cord-006870-f5w6fw6q 680 6 of of IN cord-006870-f5w6fw6q 680 7 patients patient NNS cord-006870-f5w6fw6q 680 8 with with IN cord-006870-f5w6fw6q 680 9 TBI TBI NNP cord-006870-f5w6fw6q 680 10 and and CC cord-006870-f5w6fw6q 680 11 a a DT cord-006870-f5w6fw6q 680 12 GCS GCS NNP cord-006870-f5w6fw6q 680 13 score score NN cord-006870-f5w6fw6q 680 14 of of IN cord-006870-f5w6fw6q 680 15 3 3 CD cord-006870-f5w6fw6q 680 16 . . . cord-006870-f5w6fw6q 681 1 Demographics demographic NNS cord-006870-f5w6fw6q 681 2 , , , cord-006870-f5w6fw6q 681 3 APACHE APACHE NNP cord-006870-f5w6fw6q 681 4 IV IV NNP cord-006870-f5w6fw6q 681 5 scores score NNS cord-006870-f5w6fw6q 681 6 , , , cord-006870-f5w6fw6q 681 7 pupillary pupillary JJ cord-006870-f5w6fw6q 681 8 reactivity reactivity NN cord-006870-f5w6fw6q 681 9 to to IN cord-006870-f5w6fw6q 681 10 light light NN cord-006870-f5w6fw6q 681 11 , , , cord-006870-f5w6fw6q 681 12 intracranial intracranial JJ cord-006870-f5w6fw6q 681 13 pressure pressure NN cord-006870-f5w6fw6q 681 14 ( ( -LRB- cord-006870-f5w6fw6q 681 15 ICP ICP NNP cord-006870-f5w6fw6q 681 16 ) ) -RRB- cord-006870-f5w6fw6q 681 17 , , , cord-006870-f5w6fw6q 681 18 ICP ICP NNP cord-006870-f5w6fw6q 681 19 burden burden NN cord-006870-f5w6fw6q 681 20 ( ( -LRB- cord-006870-f5w6fw6q 681 21 the the DT cord-006870-f5w6fw6q 681 22 number number NN cord-006870-f5w6fw6q 681 23 of of IN cord-006870-f5w6fw6q 681 24 days day NNS cord-006870-f5w6fw6q 681 25 with with IN cord-006870-f5w6fw6q 681 26 an an DT cord-006870-f5w6fw6q 681 27 ICP ICP NNP cord-006870-f5w6fw6q 681 28 spike spike NN cord-006870-f5w6fw6q 681 29 > > XX cord-006870-f5w6fw6q 681 30 25 25 CD cord-006870-f5w6fw6q 681 31 mm mm CD cord-006870-f5w6fw6q 681 32 Hg Hg NNP cord-006870-f5w6fw6q 681 33 as as IN cord-006870-f5w6fw6q 681 34 a a DT cord-006870-f5w6fw6q 681 35 percentage percentage NN cord-006870-f5w6fw6q 681 36 of of IN cord-006870-f5w6fw6q 681 37 the the DT cord-006870-f5w6fw6q 681 38 total total JJ cord-006870-f5w6fw6q 681 39 number number NN cord-006870-f5w6fw6q 681 40 of of IN cord-006870-f5w6fw6q 681 41 days day NNS cord-006870-f5w6fw6q 681 42 monitored monitor VBN cord-006870-f5w6fw6q 681 43 ) ) -RRB- cord-006870-f5w6fw6q 681 44 , , , cord-006870-f5w6fw6q 681 45 and and CC cord-006870-f5w6fw6q 681 46 outcome outcome NN cord-006870-f5w6fw6q 681 47 ( ( -LRB- cord-006870-f5w6fw6q 681 48 Mortality Mortality NNP cord-006870-f5w6fw6q 681 49 and and CC cord-006870-f5w6fw6q 681 50 Glasgow Glasgow NNP cord-006870-f5w6fw6q 681 51 Outcome Outcome NNP cord-006870-f5w6fw6q 681 52 Scale scale NN cord-006870-f5w6fw6q 681 53 - - HYPH cord-006870-f5w6fw6q 681 54 GOS gos NN cord-006870-f5w6fw6q 681 55 at at IN cord-006870-f5w6fw6q 681 56 6 6 CD cord-006870-f5w6fw6q 681 57 months month NNS cord-006870-f5w6fw6q 681 58 , , , cord-006870-f5w6fw6q 681 59 with with IN cord-006870-f5w6fw6q 681 60 good good JJ cord-006870-f5w6fw6q 681 61 outcome outcome NN cord-006870-f5w6fw6q 681 62 defined define VBN cord-006870-f5w6fw6q 681 63 as as IN cord-006870-f5w6fw6q 681 64 GOS GOS NNP cord-006870-f5w6fw6q 681 65 of of IN cord-006870-f5w6fw6q 681 66 4 4 CD cord-006870-f5w6fw6q 681 67 - - SYM cord-006870-f5w6fw6q 681 68 5 5 CD cord-006870-f5w6fw6q 681 69 ) ) -RRB- cord-006870-f5w6fw6q 681 70 . . . cord-006870-f5w6fw6q 682 1 Patients patient NNS cord-006870-f5w6fw6q 682 2 were be VBD cord-006870-f5w6fw6q 682 3 divided divide VBN cord-006870-f5w6fw6q 682 4 into into IN cord-006870-f5w6fw6q 682 5 2 2 CD cord-006870-f5w6fw6q 682 6 groups group NNS cord-006870-f5w6fw6q 682 7 : : : cord-006870-f5w6fw6q 683 1 Group group NN cord-006870-f5w6fw6q 683 2 1 1 CD cord-006870-f5w6fw6q 683 3 ( ( -LRB- cord-006870-f5w6fw6q 683 4 GOS gos NN cord-006870-f5w6fw6q 683 5 = = SYM cord-006870-f5w6fw6q 683 6 1 1 CD cord-006870-f5w6fw6q 683 7 - - SYM cord-006870-f5w6fw6q 683 8 3 3 CD cord-006870-f5w6fw6q 683 9 ) ) -RRB- cord-006870-f5w6fw6q 683 10 and and CC cord-006870-f5w6fw6q 683 11 Group Group NNP cord-006870-f5w6fw6q 683 12 2 2 CD cord-006870-f5w6fw6q 683 13 ( ( -LRB- cord-006870-f5w6fw6q 683 14 GOS GOS NNP cord-006870-f5w6fw6q 683 15 = = SYM cord-006870-f5w6fw6q 683 16 4 4 CD cord-006870-f5w6fw6q 683 17 - - SYM cord-006870-f5w6fw6q 683 18 5 5 CD cord-006870-f5w6fw6q 683 19 ) ) -RRB- cord-006870-f5w6fw6q 683 20 . . . cord-006870-f5w6fw6q 684 1 A a DT cord-006870-f5w6fw6q 684 2 total total NN cord-006870-f5w6fw6q 684 3 of of IN cord-006870-f5w6fw6q 684 4 62 62 CD cord-006870-f5w6fw6q 684 5 patients patient NNS cord-006870-f5w6fw6q 684 6 were be VBD cord-006870-f5w6fw6q 684 7 included include VBN cord-006870-f5w6fw6q 684 8 . . . cord-006870-f5w6fw6q 685 1 The the DT cord-006870-f5w6fw6q 685 2 overall overall JJ cord-006870-f5w6fw6q 685 3 mortality mortality NN cord-006870-f5w6fw6q 685 4 rate rate NN cord-006870-f5w6fw6q 685 5 was be VBD cord-006870-f5w6fw6q 685 6 80.6 80.6 CD cord-006870-f5w6fw6q 685 7 % % NN cord-006870-f5w6fw6q 685 8 . . . cord-006870-f5w6fw6q 686 1 At at IN cord-006870-f5w6fw6q 686 2 6-month 6-month CD cord-006870-f5w6fw6q 686 3 , , , cord-006870-f5w6fw6q 686 4 9 9 CD cord-006870-f5w6fw6q 686 5 patients patient NNS cord-006870-f5w6fw6q 686 6 ( ( -LRB- cord-006870-f5w6fw6q 686 7 14.5 14.5 CD cord-006870-f5w6fw6q 686 8 % % NN cord-006870-f5w6fw6q 686 9 ) ) -RRB- cord-006870-f5w6fw6q 686 10 achieved achieve VBD cord-006870-f5w6fw6q 686 11 a a DT cord-006870-f5w6fw6q 686 12 GOS GOS NNP cord-006870-f5w6fw6q 686 13 4 4 CD cord-006870-f5w6fw6q 686 14 - - SYM cord-006870-f5w6fw6q 686 15 5 5 CD cord-006870-f5w6fw6q 686 16 . . . cord-006870-f5w6fw6q 687 1 Compared compare VBN cord-006870-f5w6fw6q 687 2 to to IN cord-006870-f5w6fw6q 687 3 Group Group NNP cord-006870-f5w6fw6q 687 4 2 2 CD cord-006870-f5w6fw6q 687 5 ( ( -LRB- cord-006870-f5w6fw6q 687 6 n n NN cord-006870-f5w6fw6q 687 7 = = SYM cord-006870-f5w6fw6q 687 8 9 9 CD cord-006870-f5w6fw6q 687 9 ) ) -RRB- cord-006870-f5w6fw6q 687 10 , , , cord-006870-f5w6fw6q 687 11 Group Group NNP cord-006870-f5w6fw6q 687 12 1(n 1(n CD cord-006870-f5w6fw6q 687 13 = = SYM cord-006870-f5w6fw6q 687 14 53 53 CD cord-006870-f5w6fw6q 687 15 ) ) -RRB- cord-006870-f5w6fw6q 687 16 had have VBD cord-006870-f5w6fw6q 687 17 higher high JJR cord-006870-f5w6fw6q 687 18 average average JJ cord-006870-f5w6fw6q 687 19 APACHE APACHE NNP cord-006870-f5w6fw6q 687 20 IV IV NNP cord-006870-f5w6fw6q 687 21 score score NN cord-006870-f5w6fw6q 687 22 ( ( -LRB- cord-006870-f5w6fw6q 687 23 104 104 CD cord-006870-f5w6fw6q 687 24 ± ± CD cord-006870-f5w6fw6q 687 25 19 19 CD cord-006870-f5w6fw6q 687 26 vs vs IN cord-006870-f5w6fw6q 687 27 89 89 CD cord-006870-f5w6fw6q 687 28 ± ± CD cord-006870-f5w6fw6q 687 29 27 27 CD cord-006870-f5w6fw6q 687 30 , , , cord-006870-f5w6fw6q 687 31 p p NN cord-006870-f5w6fw6q 687 32 = = SYM cord-006870-f5w6fw6q 687 33 0.04 0.04 CD cord-006870-f5w6fw6q 687 34 ) ) -RRB- cord-006870-f5w6fw6q 687 35 , , , cord-006870-f5w6fw6q 687 36 more more JJR cord-006870-f5w6fw6q 687 37 patients patient NNS cord-006870-f5w6fw6q 687 38 with with IN cord-006870-f5w6fw6q 687 39 bilateral bilateral JJ cord-006870-f5w6fw6q 687 40 fixed fix VBN cord-006870-f5w6fw6q 687 41 pupils pupil NNS cord-006870-f5w6fw6q 687 42 ( ( -LRB- cord-006870-f5w6fw6q 687 43 59 59 CD cord-006870-f5w6fw6q 687 44 % % NN cord-006870-f5w6fw6q 687 45 vs vs IN cord-006870-f5w6fw6q 687 46 22 22 CD cord-006870-f5w6fw6q 687 47 % % NN cord-006870-f5w6fw6q 687 48 , , , cord-006870-f5w6fw6q 687 49 p p NN cord-006870-f5w6fw6q 687 50 = = SYM cord-006870-f5w6fw6q 687 51 0.04 0.04 CD cord-006870-f5w6fw6q 687 52 ) ) -RRB- cord-006870-f5w6fw6q 687 53 , , , cord-006870-f5w6fw6q 687 54 and and CC cord-006870-f5w6fw6q 687 55 higher high JJR cord-006870-f5w6fw6q 687 56 ICP ICP NNP cord-006870-f5w6fw6q 687 57 burden burden NN cord-006870-f5w6fw6q 687 58 ( ( -LRB- cord-006870-f5w6fw6q 687 59 50 50 CD cord-006870-f5w6fw6q 687 60 ± ± CD cord-006870-f5w6fw6q 687 61 34 34 CD cord-006870-f5w6fw6q 687 62 vs vs IN cord-006870-f5w6fw6q 687 63 0 0 CD cord-006870-f5w6fw6q 687 64 ± ± CD cord-006870-f5w6fw6q 687 65 0 0 CD cord-006870-f5w6fw6q 687 66 , , , cord-006870-f5w6fw6q 687 67 p p NN cord-006870-f5w6fw6q 687 68 = = SYM cord-006870-f5w6fw6q 687 69 0.0001 0.0001 CD cord-006870-f5w6fw6q 687 70 ) ) -RRB- cord-006870-f5w6fw6q 687 71 . . . cord-006870-f5w6fw6q 688 1 GOS GOS NNP cord-006870-f5w6fw6q 688 2 Score Score NNP cord-006870-f5w6fw6q 688 3 4 4 CD cord-006870-f5w6fw6q 688 4 - - SYM cord-006870-f5w6fw6q 688 5 5 5 CD cord-006870-f5w6fw6q 688 6 was be VBD cord-006870-f5w6fw6q 688 7 achieved achieve VBN cord-006870-f5w6fw6q 688 8 in in IN cord-006870-f5w6fw6q 688 9 41 41 CD cord-006870-f5w6fw6q 688 10 % % NN cord-006870-f5w6fw6q 688 11 of of IN cord-006870-f5w6fw6q 688 12 patients patient NNS cord-006870-f5w6fw6q 688 13 presenting present VBG cord-006870-f5w6fw6q 688 14 with with IN cord-006870-f5w6fw6q 688 15 bilateral bilateral JJ cord-006870-f5w6fw6q 688 16 reactive reactive JJ cord-006870-f5w6fw6q 688 17 pupils pupil NNS cord-006870-f5w6fw6q 688 18 versus versus IN cord-006870-f5w6fw6q 688 19 6.9 6.9 CD cord-006870-f5w6fw6q 688 20 % % NN cord-006870-f5w6fw6q 688 21 of of IN cord-006870-f5w6fw6q 688 22 patients patient NNS cord-006870-f5w6fw6q 688 23 presenting present VBG cord-006870-f5w6fw6q 688 24 with with IN cord-006870-f5w6fw6q 688 25 bilateral bilateral JJ cord-006870-f5w6fw6q 688 26 fixed fix VBN cord-006870-f5w6fw6q 688 27 pupils pupil NNS cord-006870-f5w6fw6q 688 28 ( ( -LRB- cord-006870-f5w6fw6q 688 29 p p NN cord-006870-f5w6fw6q 688 30 = = SYM cord-006870-f5w6fw6q 688 31 0.005 0.005 CD cord-006870-f5w6fw6q 688 32 ) ) -RRB- cord-006870-f5w6fw6q 688 33 . . . cord-006870-f5w6fw6q 689 1 14.5 14.5 CD cord-006870-f5w6fw6q 689 2 % % NN cord-006870-f5w6fw6q 689 3 of of IN cord-006870-f5w6fw6q 689 4 patients patient NNS cord-006870-f5w6fw6q 689 5 with with IN cord-006870-f5w6fw6q 689 6 TBI TBI NNP cord-006870-f5w6fw6q 689 7 and and CC cord-006870-f5w6fw6q 689 8 a a DT cord-006870-f5w6fw6q 689 9 GCS GCS NNP cord-006870-f5w6fw6q 689 10 of of IN cord-006870-f5w6fw6q 689 11 3 3 CD cord-006870-f5w6fw6q 689 12 at at IN cord-006870-f5w6fw6q 689 13 presentation presentation NN cord-006870-f5w6fw6q 689 14 achieved achieve VBD cord-006870-f5w6fw6q 689 15 a a DT cord-006870-f5w6fw6q 689 16 good good JJ cord-006870-f5w6fw6q 689 17 outcome outcome NN cord-006870-f5w6fw6q 689 18 at at IN cord-006870-f5w6fw6q 689 19 6 6 CD cord-006870-f5w6fw6q 689 20 months month NNS cord-006870-f5w6fw6q 689 21 . . . cord-006870-f5w6fw6q 690 1 APACHE APACHE NNP cord-006870-f5w6fw6q 690 2 IV IV NNP cord-006870-f5w6fw6q 690 3 scores score NNS cord-006870-f5w6fw6q 690 4 , , , cord-006870-f5w6fw6q 690 5 ICP ICP NNP cord-006870-f5w6fw6q 690 6 burden burden NN cord-006870-f5w6fw6q 690 7 , , , cord-006870-f5w6fw6q 690 8 and and CC cord-006870-f5w6fw6q 690 9 pupillary pupillary JJ cord-006870-f5w6fw6q 690 10 reactivity reactivity NN cord-006870-f5w6fw6q 690 11 were be VBD cord-006870-f5w6fw6q 690 12 significant significant JJ cord-006870-f5w6fw6q 690 13 predictors predictor NNS cord-006870-f5w6fw6q 690 14 of of IN cord-006870-f5w6fw6q 690 15 outcome outcome NN cord-006870-f5w6fw6q 690 16 . . . cord-006870-f5w6fw6q 691 1 We -PRON- PRP cord-006870-f5w6fw6q 691 2 believe believe VBP cord-006870-f5w6fw6q 691 3 that that IN cord-006870-f5w6fw6q 691 4 patients patient NNS cord-006870-f5w6fw6q 691 5 with with IN cord-006870-f5w6fw6q 691 6 severe severe JJ cord-006870-f5w6fw6q 691 7 TBI TBI NNP cord-006870-f5w6fw6q 691 8 who who WP cord-006870-f5w6fw6q 691 9 present present VBP cord-006870-f5w6fw6q 691 10 with with IN cord-006870-f5w6fw6q 691 11 a a DT cord-006870-f5w6fw6q 691 12 GCS GCS NNP cord-006870-f5w6fw6q 691 13 of of IN cord-006870-f5w6fw6q 691 14 3 3 CD cord-006870-f5w6fw6q 691 15 should should MD cord-006870-f5w6fw6q 691 16 still still RB cord-006870-f5w6fw6q 691 17 be be VB cord-006870-f5w6fw6q 691 18 treated treat VBN cord-006870-f5w6fw6q 691 19 aggressively aggressively RB cord-006870-f5w6fw6q 691 20 initially initially RB cord-006870-f5w6fw6q 691 21 since since IN cord-006870-f5w6fw6q 691 22 a a DT cord-006870-f5w6fw6q 691 23 good good JJ cord-006870-f5w6fw6q 691 24 outcome outcome NN cord-006870-f5w6fw6q 691 25 can can MD cord-006870-f5w6fw6q 691 26 be be VB cord-006870-f5w6fw6q 691 27 obtained obtain VBN cord-006870-f5w6fw6q 691 28 in in IN cord-006870-f5w6fw6q 691 29 a a DT cord-006870-f5w6fw6q 691 30 significant significant JJ cord-006870-f5w6fw6q 691 31 proportion proportion NN cord-006870-f5w6fw6q 691 32 of of IN cord-006870-f5w6fw6q 691 33 patients patient NNS cord-006870-f5w6fw6q 691 34 . . . cord-006870-f5w6fw6q 692 1 Elevated elevated JJ cord-006870-f5w6fw6q 692 2 circulating circulate VBG cord-006870-f5w6fw6q 692 3 catecholamine catecholamine NN cord-006870-f5w6fw6q 692 4 levels level NNS cord-006870-f5w6fw6q 692 5 are be VBP cord-006870-f5w6fw6q 692 6 independently independently RB cord-006870-f5w6fw6q 692 7 associated associate VBN cord-006870-f5w6fw6q 692 8 with with IN cord-006870-f5w6fw6q 692 9 functional functional JJ cord-006870-f5w6fw6q 692 10 outcome outcome NN cord-006870-f5w6fw6q 692 11 and and CC cord-006870-f5w6fw6q 692 12 mortality mortality NN cord-006870-f5w6fw6q 692 13 after after IN cord-006870-f5w6fw6q 692 14 isolated isolate VBN cord-006870-f5w6fw6q 692 15 traumatic traumatic JJ cord-006870-f5w6fw6q 692 16 brain brain NN cord-006870-f5w6fw6q 692 17 injury injury NN cord-006870-f5w6fw6q 692 18 ( ( -LRB- cord-006870-f5w6fw6q 692 19 TBI TBI NNP cord-006870-f5w6fw6q 692 20 ) ) -RRB- cord-006870-f5w6fw6q 692 21 . . . cord-006870-f5w6fw6q 693 1 We -PRON- PRP cord-006870-f5w6fw6q 693 2 assessed assess VBD cord-006870-f5w6fw6q 693 3 the the DT cord-006870-f5w6fw6q 693 4 ability ability NN cord-006870-f5w6fw6q 693 5 of of IN cord-006870-f5w6fw6q 693 6 peripheral peripheral JJ cord-006870-f5w6fw6q 693 7 catecholamine catecholamine NN cord-006870-f5w6fw6q 693 8 levels level NNS cord-006870-f5w6fw6q 693 9 to to TO cord-006870-f5w6fw6q 693 10 improve improve VB cord-006870-f5w6fw6q 693 11 the the DT cord-006870-f5w6fw6q 693 12 prognostic prognostic JJ cord-006870-f5w6fw6q 693 13 performance performance NN cord-006870-f5w6fw6q 693 14 of of IN cord-006870-f5w6fw6q 693 15 the the DT cord-006870-f5w6fw6q 693 16 CRASH crash NN cord-006870-f5w6fw6q 693 17 and and CC cord-006870-f5w6fw6q 693 18 IMPACT IMPACT NNP cord-006870-f5w6fw6q 693 19 - - HYPH cord-006870-f5w6fw6q 693 20 TBI tbi NN cord-006870-f5w6fw6q 693 21 models model NNS cord-006870-f5w6fw6q 693 22 . . . cord-006870-f5w6fw6q 694 1 Prospective prospective JJ cord-006870-f5w6fw6q 694 2 , , , cord-006870-f5w6fw6q 694 3 observational observational JJ cord-006870-f5w6fw6q 694 4 , , , cord-006870-f5w6fw6q 694 5 multicenter multicenter JJ cord-006870-f5w6fw6q 694 6 cohort cohort NN cord-006870-f5w6fw6q 694 7 study study NN cord-006870-f5w6fw6q 694 8 , , , cord-006870-f5w6fw6q 694 9 conducted conduct VBN cord-006870-f5w6fw6q 694 10 at at IN cord-006870-f5w6fw6q 694 11 three three CD cord-006870-f5w6fw6q 694 12 Level Level NNP cord-006870-f5w6fw6q 694 13 1 1 CD cord-006870-f5w6fw6q 694 14 Trauma Trauma NNP cord-006870-f5w6fw6q 694 15 Centers Centers NNPS cord-006870-f5w6fw6q 694 16 in in IN cord-006870-f5w6fw6q 694 17 Canada Canada NNP cord-006870-f5w6fw6q 694 18 and and CC cord-006870-f5w6fw6q 694 19 USA USA NNP cord-006870-f5w6fw6q 694 20 . . . cord-006870-f5w6fw6q 695 1 Epinephrine epinephrine NN cord-006870-f5w6fw6q 695 2 ( ( -LRB- cord-006870-f5w6fw6q 695 3 Epi Epi NNP cord-006870-f5w6fw6q 695 4 ) ) -RRB- cord-006870-f5w6fw6q 695 5 and and CC cord-006870-f5w6fw6q 695 6 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 695 7 ( ( -LRB- cord-006870-f5w6fw6q 695 8 NE NE NNP cord-006870-f5w6fw6q 695 9 ) ) -RRB- cord-006870-f5w6fw6q 695 10 concentrations concentration NNS cord-006870-f5w6fw6q 695 11 were be VBD cord-006870-f5w6fw6q 695 12 measured measure VBN cord-006870-f5w6fw6q 695 13 in in IN cord-006870-f5w6fw6q 695 14 the the DT cord-006870-f5w6fw6q 695 15 peripheral peripheral JJ cord-006870-f5w6fw6q 695 16 blood blood NN cord-006870-f5w6fw6q 695 17 at at IN cord-006870-f5w6fw6q 695 18 admission admission NN cord-006870-f5w6fw6q 695 19 ( ( -LRB- cord-006870-f5w6fw6q 695 20 baseline baseline NN cord-006870-f5w6fw6q 695 21 ) ) -RRB- cord-006870-f5w6fw6q 695 22 , , , cord-006870-f5w6fw6q 695 23 6 6 CD cord-006870-f5w6fw6q 695 24 , , , cord-006870-f5w6fw6q 695 25 12 12 CD cord-006870-f5w6fw6q 695 26 and and CC cord-006870-f5w6fw6q 695 27 24h 24h NNS cord-006870-f5w6fw6q 695 28 after after IN cord-006870-f5w6fw6q 695 29 trauma trauma NN cord-006870-f5w6fw6q 695 30 . . . cord-006870-f5w6fw6q 696 1 Outcome outcome NN cord-006870-f5w6fw6q 696 2 was be VBD cord-006870-f5w6fw6q 696 3 assessed assess VBN cord-006870-f5w6fw6q 696 4 at at IN cord-006870-f5w6fw6q 696 5 6 6 CD cord-006870-f5w6fw6q 696 6 months month NNS cord-006870-f5w6fw6q 696 7 and and CC cord-006870-f5w6fw6q 696 8 dichotomized dichotomize VBN cord-006870-f5w6fw6q 696 9 into into IN cord-006870-f5w6fw6q 696 10 favorable favorable JJ cord-006870-f5w6fw6q 696 11 [ [ -LRB- cord-006870-f5w6fw6q 696 12 Extended extended JJ cord-006870-f5w6fw6q 696 13 Glasgow Glasgow NNP cord-006870-f5w6fw6q 696 14 Outcome outcome NN cord-006870-f5w6fw6q 696 15 Scale scale NN cord-006870-f5w6fw6q 696 16 ( ( -LRB- cord-006870-f5w6fw6q 696 17 GO go VB cord-006870-f5w6fw6q 696 18 -TBI -TBI JJR cord-006870-f5w6fw6q 696 19 models model NNS cord-006870-f5w6fw6q 696 20 , , , cord-006870-f5w6fw6q 696 21 which which WDT cord-006870-f5w6fw6q 696 22 identified identify VBD cord-006870-f5w6fw6q 696 23 core core JJ cord-006870-f5w6fw6q 696 24 prognostic prognostic JJ cord-006870-f5w6fw6q 696 25 markers marker NNS cord-006870-f5w6fw6q 696 26 of of IN cord-006870-f5w6fw6q 696 27 severe severe JJ cord-006870-f5w6fw6q 696 28 TBI tbi NN cord-006870-f5w6fw6q 696 29 . . . cord-006870-f5w6fw6q 697 1 The the DT cord-006870-f5w6fw6q 697 2 baseline baseline JJ cord-006870-f5w6fw6q 697 3 model model NN cord-006870-f5w6fw6q 697 4 ( ( -LRB- cord-006870-f5w6fw6q 697 5 M1 M1 NNP cord-006870-f5w6fw6q 697 6 ) ) -RRB- cord-006870-f5w6fw6q 697 7 included include VBD cord-006870-f5w6fw6q 697 8 age age NN cord-006870-f5w6fw6q 697 9 , , , cord-006870-f5w6fw6q 697 10 GCS GCS NNP cord-006870-f5w6fw6q 697 11 and and CC cord-006870-f5w6fw6q 697 12 pupillary pupillary JJ cord-006870-f5w6fw6q 697 13 size size NN cord-006870-f5w6fw6q 697 14 / / SYM cord-006870-f5w6fw6q 697 15 reactivity reactivity NN cord-006870-f5w6fw6q 697 16 . . . cord-006870-f5w6fw6q 698 1 The the DT cord-006870-f5w6fw6q 698 2 model model NN cord-006870-f5w6fw6q 698 3 2 2 CD cord-006870-f5w6fw6q 698 4 ( ( -LRB- cord-006870-f5w6fw6q 698 5 M2 M2 NNP cord-006870-f5w6fw6q 698 6 ) ) -RRB- cord-006870-f5w6fw6q 698 7 included include VBD cord-006870-f5w6fw6q 698 8 M1 M1 NNP cord-006870-f5w6fw6q 698 9 + + CC cord-006870-f5w6fw6q 698 10 hypoxia hypoxia NN cord-006870-f5w6fw6q 698 11 , , , cord-006870-f5w6fw6q 698 12 hypotension hypotension NN cord-006870-f5w6fw6q 698 13 and and CC cord-006870-f5w6fw6q 698 14 Marshall Marshall NNP cord-006870-f5w6fw6q 698 15 CT CT NNP cord-006870-f5w6fw6q 698 16 classification classification NN cord-006870-f5w6fw6q 698 17 . . . cord-006870-f5w6fw6q 699 1 Model model NN cord-006870-f5w6fw6q 699 2 3 3 CD cord-006870-f5w6fw6q 699 3 and and CC cord-006870-f5w6fw6q 699 4 4 4 CD cord-006870-f5w6fw6q 699 5 included include VBD cord-006870-f5w6fw6q 699 6 M1 M1 NNP cord-006870-f5w6fw6q 699 7 + + CC cord-006870-f5w6fw6q 699 8 Epi Epi NNP cord-006870-f5w6fw6q 699 9 levels level NNS cord-006870-f5w6fw6q 699 10 , , , cord-006870-f5w6fw6q 699 11 and and CC cord-006870-f5w6fw6q 699 12 M1 M1 NNP cord-006870-f5w6fw6q 699 13 + + CC cord-006870-f5w6fw6q 699 14 NE NE NNP cord-006870-f5w6fw6q 699 15 levels level NNS cord-006870-f5w6fw6q 699 16 , , , cord-006870-f5w6fw6q 699 17 respectively respectively RB cord-006870-f5w6fw6q 699 18 . . . cord-006870-f5w6fw6q 700 1 The the DT cord-006870-f5w6fw6q 700 2 risk risk NN cord-006870-f5w6fw6q 700 3 models model NNS cord-006870-f5w6fw6q 700 4 performance performance NN cord-006870-f5w6fw6q 700 5 was be VBD cord-006870-f5w6fw6q 700 6 assessed assess VBN cord-006870-f5w6fw6q 700 7 by by IN cord-006870-f5w6fw6q 700 8 comparing compare VBG cord-006870-f5w6fw6q 700 9 receiver receiver NN cord-006870-f5w6fw6q 700 10 operating operating NN cord-006870-f5w6fw6q 700 11 characteristic characteristic NN cord-006870-f5w6fw6q 700 12 ( ( -LRB- cord-006870-f5w6fw6q 700 13 ROC ROC NNP cord-006870-f5w6fw6q 700 14 ) ) -RRB- cord-006870-f5w6fw6q 700 15 curves curve NNS cord-006870-f5w6fw6q 700 16 , , , cord-006870-f5w6fw6q 700 17 and and CC cord-006870-f5w6fw6q 700 18 by by IN cord-006870-f5w6fw6q 700 19 the the DT cord-006870-f5w6fw6q 700 20 use use NN cord-006870-f5w6fw6q 700 21 of of IN cord-006870-f5w6fw6q 700 22 integrated integrated JJ cord-006870-f5w6fw6q 700 23 discrimination discrimination NN cord-006870-f5w6fw6q 700 24 improvement improvement NN cord-006870-f5w6fw6q 700 25 ( ( -LRB- cord-006870-f5w6fw6q 700 26 IDI IDI NNP cord-006870-f5w6fw6q 700 27 ) ) -RRB- cord-006870-f5w6fw6q 700 28 index index NN cord-006870-f5w6fw6q 700 29 . . . cord-006870-f5w6fw6q 701 1 M3 M3 NNP cord-006870-f5w6fw6q 701 2 had have VBD cord-006870-f5w6fw6q 701 3 significantly significantly RB cord-006870-f5w6fw6q 701 4 higher high JJR cord-006870-f5w6fw6q 701 5 ROC ROC NNP cord-006870-f5w6fw6q 701 6 and and CC cord-006870-f5w6fw6q 701 7 IDI IDI NNP cord-006870-f5w6fw6q 701 8 than than IN cord-006870-f5w6fw6q 701 9 the the DT cord-006870-f5w6fw6q 701 10 baseline baseline JJ cord-006870-f5w6fw6q 701 11 model model NN cord-006870-f5w6fw6q 701 12 ( ( -LRB- cord-006870-f5w6fw6q 701 13 M1 M1 NNP cord-006870-f5w6fw6q 701 14 ) ) -RRB- cord-006870-f5w6fw6q 701 15 , , , cord-006870-f5w6fw6q 701 16 to to TO cord-006870-f5w6fw6q 701 17 predict predict VB cord-006870-f5w6fw6q 701 18 mortality mortality NN cord-006870-f5w6fw6q 701 19 . . . cord-006870-f5w6fw6q 702 1 M3 M3 NNP cord-006870-f5w6fw6q 702 2 had have VBD cord-006870-f5w6fw6q 702 3 a a DT cord-006870-f5w6fw6q 702 4 ROC ROC NNP cord-006870-f5w6fw6q 702 5 = = SYM cord-006870-f5w6fw6q 702 6 0.930 0.930 CD cord-006870-f5w6fw6q 703 1 ( ( -LRB- cord-006870-f5w6fw6q 703 2 0.891 0.891 CD cord-006870-f5w6fw6q 703 3 -0.968 -0.968 NNP cord-006870-f5w6fw6q 703 4 , , , cord-006870-f5w6fw6q 703 5 p p NN cord-006870-f5w6fw6q 703 6 = = SYM cord-006870-f5w6fw6q 703 7 0.012 0.012 CD cord-006870-f5w6fw6q 703 8 ) ) -RRB- cord-006870-f5w6fw6q 703 9 and and CC cord-006870-f5w6fw6q 703 10 IDI IDI NNP cord-006870-f5w6fw6q 703 11 = = SYM cord-006870-f5w6fw6q 703 12 0.14 0.14 CD cord-006870-f5w6fw6q 703 13 ( ( -LRB- cord-006870-f5w6fw6q 703 14 p p NN cord-006870-f5w6fw6q 703 15 = = SYM cord-006870-f5w6fw6q 703 16 0.0001 0.0001 CD cord-006870-f5w6fw6q 703 17 ) ) -RRB- cord-006870-f5w6fw6q 703 18 . . . cord-006870-f5w6fw6q 704 1 The the DT cord-006870-f5w6fw6q 704 2 prediction prediction NN cord-006870-f5w6fw6q 704 3 of of IN cord-006870-f5w6fw6q 704 4 mortality mortality NN cord-006870-f5w6fw6q 704 5 was be VBD cord-006870-f5w6fw6q 704 6 not not RB cord-006870-f5w6fw6q 704 7 improved improve VBN cord-006870-f5w6fw6q 704 8 by by IN cord-006870-f5w6fw6q 704 9 including include VBG cord-006870-f5w6fw6q 704 10 NE NE NNP cord-006870-f5w6fw6q 704 11 [ [ -LRB- cord-006870-f5w6fw6q 704 12 M4 M4 NNP cord-006870-f5w6fw6q 704 13 = = SYM cord-006870-f5w6fw6q 704 14 ROC ROC NNP cord-006870-f5w6fw6q 704 15 = = SYM cord-006870-f5w6fw6q 704 16 0.896 0.896 CD cord-006870-f5w6fw6q 704 17 ( ( -LRB- cord-006870-f5w6fw6q 704 18 0.848 0.848 CD cord-006870-f5w6fw6q 705 1 -0.943 -0.943 NNP cord-006870-f5w6fw6q 705 2 , , , cord-006870-f5w6fw6q 705 3 p p NN cord-006870-f5w6fw6q 705 4 = = SYM cord-006870-f5w6fw6q 705 5 0.245 0.245 CD cord-006870-f5w6fw6q 705 6 ) ) -RRB- cord-006870-f5w6fw6q 706 1 and and CC cord-006870-f5w6fw6q 706 2 IDI IDI NNP cord-006870-f5w6fw6q 706 3 = = SYM cord-006870-f5w6fw6q 706 4 0.02 0.02 CD cord-006870-f5w6fw6q 706 5 ( ( -LRB- cord-006870-f5w6fw6q 706 6 p=0.124 p=0.124 NNP cord-006870-f5w6fw6q 706 7 ) ) -RRB- cord-006870-f5w6fw6q 706 8 ] ] -RRB- cord-006870-f5w6fw6q 706 9 . . . cord-006870-f5w6fw6q 707 1 The the DT cord-006870-f5w6fw6q 707 2 integrated integrated JJ cord-006870-f5w6fw6q 707 3 discrimination discrimination NN cord-006870-f5w6fw6q 707 4 improvement improvement NN cord-006870-f5w6fw6q 707 5 index index NN cord-006870-f5w6fw6q 707 6 indicated indicate VBD cord-006870-f5w6fw6q 707 7 the the DT cord-006870-f5w6fw6q 707 8 prediction prediction NN cord-006870-f5w6fw6q 707 9 of of IN cord-006870-f5w6fw6q 707 10 unfavourable unfavourable JJ cord-006870-f5w6fw6q 707 11 outcome outcome NN cord-006870-f5w6fw6q 707 12 by by IN cord-006870-f5w6fw6q 707 13 the the DT cord-006870-f5w6fw6q 707 14 baseline baseline JJ cord-006870-f5w6fw6q 707 15 model model NN cord-006870-f5w6fw6q 707 16 was be VBD cord-006870-f5w6fw6q 707 17 improved improve VBN cord-006870-f5w6fw6q 707 18 by by IN cord-006870-f5w6fw6q 707 19 including include VBG cord-006870-f5w6fw6q 707 20 EPi EPi NNS cord-006870-f5w6fw6q 707 21 ( ( -LRB- cord-006870-f5w6fw6q 707 22 IDI IDI NNP cord-006870-f5w6fw6q 707 23 = = SYM cord-006870-f5w6fw6q 707 24 0.04 0.04 CD cord-006870-f5w6fw6q 707 25 , , , cord-006870-f5w6fw6q 707 26 p=0.024 p=0.024 NNP cord-006870-f5w6fw6q 707 27 ) ) -RRB- cord-006870-f5w6fw6q 707 28 , , , cord-006870-f5w6fw6q 707 29 and and CC cord-006870-f5w6fw6q 707 30 NE NE NNP cord-006870-f5w6fw6q 707 31 ( ( -LRB- cord-006870-f5w6fw6q 707 32 IDI IDI NNP cord-006870-f5w6fw6q 707 33 = = SYM cord-006870-f5w6fw6q 707 34 0.08 0.08 CD cord-006870-f5w6fw6q 707 35 , , , cord-006870-f5w6fw6q 707 36 p=0.0002 p=0.0002 NNP cord-006870-f5w6fw6q 707 37 ) ) -RRB- cord-006870-f5w6fw6q 707 38 in in IN cord-006870-f5w6fw6q 707 39 the the DT cord-006870-f5w6fw6q 707 40 models model NNS cord-006870-f5w6fw6q 707 41 . . . cord-006870-f5w6fw6q 708 1 Catecholamine Catecholamine NNP cord-006870-f5w6fw6q 708 2 levels level NNS cord-006870-f5w6fw6q 708 3 improved improve VBD cord-006870-f5w6fw6q 708 4 risk risk NN cord-006870-f5w6fw6q 708 5 models model NNS cord-006870-f5w6fw6q 708 6 performance performance NN cord-006870-f5w6fw6q 708 7 to to TO cord-006870-f5w6fw6q 708 8 predict predict VB cord-006870-f5w6fw6q 708 9 mortality mortality NN cord-006870-f5w6fw6q 708 10 and and CC cord-006870-f5w6fw6q 708 11 unfavorable unfavorable JJ cord-006870-f5w6fw6q 708 12 outcome outcome NN cord-006870-f5w6fw6q 708 13 after after IN cord-006870-f5w6fw6q 708 14 traumatic traumatic JJ cord-006870-f5w6fw6q 708 15 brain brain NN cord-006870-f5w6fw6q 708 16 injury injury NN cord-006870-f5w6fw6q 708 17 . . . cord-006870-f5w6fw6q 709 1 Following follow VBG cord-006870-f5w6fw6q 709 2 traumatic traumatic JJ cord-006870-f5w6fw6q 709 3 brain brain NN cord-006870-f5w6fw6q 709 4 injury injury NN cord-006870-f5w6fw6q 709 5 ( ( -LRB- cord-006870-f5w6fw6q 709 6 TBI TBI NNP cord-006870-f5w6fw6q 709 7 ) ) -RRB- cord-006870-f5w6fw6q 709 8 , , , cord-006870-f5w6fw6q 709 9 depression depression NN cord-006870-f5w6fw6q 709 10 is be VBZ cord-006870-f5w6fw6q 709 11 common common JJ cord-006870-f5w6fw6q 709 12 and and CC cord-006870-f5w6fw6q 709 13 may may MD cord-006870-f5w6fw6q 709 14 influence influence VB cord-006870-f5w6fw6q 709 15 recovery recovery NN cord-006870-f5w6fw6q 709 16 . . . cord-006870-f5w6fw6q 710 1 Small small JJ cord-006870-f5w6fw6q 710 2 trials trial NNS cord-006870-f5w6fw6q 710 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 710 4 that that IN cord-006870-f5w6fw6q 710 5 various various JJ cord-006870-f5w6fw6q 710 6 drugs drug NNS cord-006870-f5w6fw6q 710 7 are be VBP cord-006870-f5w6fw6q 710 8 beneficial beneficial JJ cord-006870-f5w6fw6q 710 9 in in IN cord-006870-f5w6fw6q 710 10 managing manage VBG cord-006870-f5w6fw6q 710 11 depression depression NN cord-006870-f5w6fw6q 710 12 following follow VBG cord-006870-f5w6fw6q 710 13 TBI TBI NNP cord-006870-f5w6fw6q 710 14 , , , cord-006870-f5w6fw6q 710 15 but but CC cord-006870-f5w6fw6q 710 16 no no DT cord-006870-f5w6fw6q 710 17 large large JJ cord-006870-f5w6fw6q 710 18 , , , cord-006870-f5w6fw6q 710 19 definitive definitive JJ cord-006870-f5w6fw6q 710 20 study study NN cord-006870-f5w6fw6q 710 21 has have VBZ cord-006870-f5w6fw6q 710 22 been be VBN cord-006870-f5w6fw6q 710 23 conducted conduct VBN cord-006870-f5w6fw6q 710 24 . . . cord-006870-f5w6fw6q 711 1 We -PRON- PRP cord-006870-f5w6fw6q 711 2 performed perform VBD cord-006870-f5w6fw6q 711 3 a a DT cord-006870-f5w6fw6q 711 4 meta meta NN cord-006870-f5w6fw6q 711 5 - - HYPH cord-006870-f5w6fw6q 711 6 analysis analysis NN cord-006870-f5w6fw6q 711 7 to to TO cord-006870-f5w6fw6q 711 8 estimate estimate VB cord-006870-f5w6fw6q 711 9 the the DT cord-006870-f5w6fw6q 711 10 potential potential JJ cord-006870-f5w6fw6q 711 11 benefit benefit NN cord-006870-f5w6fw6q 711 12 of of IN cord-006870-f5w6fw6q 711 13 anti anti JJ cord-006870-f5w6fw6q 711 14 - - JJ cord-006870-f5w6fw6q 711 15 depressant depressant JJ cord-006870-f5w6fw6q 711 16 medications medication NNS cord-006870-f5w6fw6q 711 17 following follow VBG cord-006870-f5w6fw6q 711 18 TBI TBI NNP cord-006870-f5w6fw6q 711 19 . . . cord-006870-f5w6fw6q 712 1 Multiple multiple JJ cord-006870-f5w6fw6q 712 2 databases database NNS cord-006870-f5w6fw6q 712 3 were be VBD cord-006870-f5w6fw6q 712 4 searched search VBN cord-006870-f5w6fw6q 712 5 using use VBG cord-006870-f5w6fw6q 712 6 the the DT cord-006870-f5w6fw6q 712 7 terms term NNS cord-006870-f5w6fw6q 712 8 " " `` cord-006870-f5w6fw6q 712 9 anti anti JJ cord-006870-f5w6fw6q 712 10 - - JJ cord-006870-f5w6fw6q 712 11 depressant depressant JJ cord-006870-f5w6fw6q 712 12 TBI TBI NNP cord-006870-f5w6fw6q 712 13 , , , cord-006870-f5w6fw6q 712 14 " " '' cord-006870-f5w6fw6q 712 15 and and CC cord-006870-f5w6fw6q 712 16 " " `` cord-006870-f5w6fw6q 712 17 depression depression NN cord-006870-f5w6fw6q 712 18 treatment treatment NN cord-006870-f5w6fw6q 712 19 TBI TBI NNP cord-006870-f5w6fw6q 712 20 " " '' cord-006870-f5w6fw6q 712 21 to to TO cord-006870-f5w6fw6q 712 22 find find VB cord-006870-f5w6fw6q 712 23 prospective prospective JJ cord-006870-f5w6fw6q 712 24 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 712 25 treatment treatment NN cord-006870-f5w6fw6q 712 26 studies study NNS cord-006870-f5w6fw6q 712 27 of of IN cord-006870-f5w6fw6q 712 28 depression depression NN cord-006870-f5w6fw6q 712 29 following follow VBG cord-006870-f5w6fw6q 712 30 TBI TBI NNP cord-006870-f5w6fw6q 712 31 . . . cord-006870-f5w6fw6q 713 1 Studies study NNS cord-006870-f5w6fw6q 713 2 were be VBD cord-006870-f5w6fw6q 713 3 excluded exclude VBN cord-006870-f5w6fw6q 713 4 if if IN cord-006870-f5w6fw6q 713 5 they -PRON- PRP cord-006870-f5w6fw6q 713 6 did do VBD cord-006870-f5w6fw6q 713 7 not not RB cord-006870-f5w6fw6q 713 8 measure measure VB cord-006870-f5w6fw6q 713 9 depression depression NN cord-006870-f5w6fw6q 713 10 as as IN cord-006870-f5w6fw6q 713 11 an an DT cord-006870-f5w6fw6q 713 12 outcome outcome NN cord-006870-f5w6fw6q 713 13 . . . cord-006870-f5w6fw6q 714 1 Effect effect NN cord-006870-f5w6fw6q 714 2 sizes size NNS cord-006870-f5w6fw6q 714 3 for for IN cord-006870-f5w6fw6q 714 4 anti anti JJ cord-006870-f5w6fw6q 714 5 - - JJ cord-006870-f5w6fw6q 714 6 depressant depressant JJ cord-006870-f5w6fw6q 714 7 medications medication NNS cord-006870-f5w6fw6q 714 8 in in IN cord-006870-f5w6fw6q 714 9 post post JJ cord-006870-f5w6fw6q 714 10 - - JJ cord-006870-f5w6fw6q 714 11 TBI tbi JJ cord-006870-f5w6fw6q 714 12 patients patient NNS cord-006870-f5w6fw6q 714 13 were be VBD cord-006870-f5w6fw6q 714 14 calculated calculate VBN cord-006870-f5w6fw6q 714 15 for for IN cord-006870-f5w6fw6q 714 16 within within IN cord-006870-f5w6fw6q 714 17 - - HYPH cord-006870-f5w6fw6q 714 18 subjects subject NNS cord-006870-f5w6fw6q 714 19 designs design NNS cord-006870-f5w6fw6q 714 20 that that WDT cord-006870-f5w6fw6q 714 21 examined examine VBD cord-006870-f5w6fw6q 714 22 change change NN cord-006870-f5w6fw6q 714 23 from from IN cord-006870-f5w6fw6q 714 24 baseline baseline NN cord-006870-f5w6fw6q 714 25 after after IN cord-006870-f5w6fw6q 714 26 receiving receive VBG cord-006870-f5w6fw6q 714 27 medical medical JJ cord-006870-f5w6fw6q 714 28 treatment treatment NN cord-006870-f5w6fw6q 714 29 and and CC cord-006870-f5w6fw6q 714 30 treatment treatment NN cord-006870-f5w6fw6q 714 31 - - HYPH cord-006870-f5w6fw6q 714 32 placebo placebo NN cord-006870-f5w6fw6q 714 33 designs design NNS cord-006870-f5w6fw6q 714 34 that that WDT cord-006870-f5w6fw6q 714 35 examined examine VBD cord-006870-f5w6fw6q 714 36 the the DT cord-006870-f5w6fw6q 714 37 differences difference NNS cord-006870-f5w6fw6q 714 38 between between IN cord-006870-f5w6fw6q 714 39 anti anti JJ cord-006870-f5w6fw6q 714 40 - - NNS cord-006870-f5w6fw6q 714 41 depressants depressant NNS cord-006870-f5w6fw6q 714 42 and and CC cord-006870-f5w6fw6q 714 43 placebo placebo NN cord-006870-f5w6fw6q 714 44 groups group NNS cord-006870-f5w6fw6q 714 45 . . . cord-006870-f5w6fw6q 715 1 A a DT cord-006870-f5w6fw6q 715 2 random random JJ cord-006870-f5w6fw6q 715 3 effects effect NNS cord-006870-f5w6fw6q 715 4 model model NN cord-006870-f5w6fw6q 715 5 was be VBD cord-006870-f5w6fw6q 715 6 used use VBN cord-006870-f5w6fw6q 715 7 for for IN cord-006870-f5w6fw6q 715 8 both both DT cord-006870-f5w6fw6q 715 9 analyses analysis NNS cord-006870-f5w6fw6q 715 10 . . . cord-006870-f5w6fw6q 716 1 Of of IN cord-006870-f5w6fw6q 716 2 923 923 CD cord-006870-f5w6fw6q 716 3 titles title NNS cord-006870-f5w6fw6q 716 4 screened screen VBN cord-006870-f5w6fw6q 716 5 , , , cord-006870-f5w6fw6q 716 6 10 10 CD cord-006870-f5w6fw6q 716 7 studies study NNS cord-006870-f5w6fw6q 716 8 were be VBD cord-006870-f5w6fw6q 716 9 included include VBN cord-006870-f5w6fw6q 716 10 , , , cord-006870-f5w6fw6q 716 11 with with IN cord-006870-f5w6fw6q 716 12 288 288 CD cord-006870-f5w6fw6q 716 13 total total JJ cord-006870-f5w6fw6q 716 14 patients patient NNS cord-006870-f5w6fw6q 716 15 . . . cord-006870-f5w6fw6q 717 1 Medications medication NNS cord-006870-f5w6fw6q 717 2 evaluated evaluate VBN cord-006870-f5w6fw6q 717 3 included include VBD cord-006870-f5w6fw6q 717 4 selective selective JJ cord-006870-f5w6fw6q 717 5 serotonin serotonin NN cord-006870-f5w6fw6q 717 6 reuptake reuptake NN cord-006870-f5w6fw6q 717 7 inhibitors inhibitor NNS cord-006870-f5w6fw6q 717 8 , , , cord-006870-f5w6fw6q 717 9 monoamine monoamine NN cord-006870-f5w6fw6q 717 10 oxidase oxidase NN cord-006870-f5w6fw6q 717 11 inhibitors inhibitor NNS cord-006870-f5w6fw6q 717 12 , , , cord-006870-f5w6fw6q 717 13 and and CC cord-006870-f5w6fw6q 717 14 tricyclic tricyclic NN cord-006870-f5w6fw6q 717 15 antidepressants antidepressant NNS cord-006870-f5w6fw6q 717 16 . . . cord-006870-f5w6fw6q 718 1 Pooled pool VBN cord-006870-f5w6fw6q 718 2 estimates estimate NNS cord-006870-f5w6fw6q 718 3 showed show VBD cord-006870-f5w6fw6q 718 4 significant significant JJ cord-006870-f5w6fw6q 718 5 reduction reduction NN cord-006870-f5w6fw6q 718 6 in in IN cord-006870-f5w6fw6q 718 7 depression depression NN cord-006870-f5w6fw6q 718 8 scores score NNS cord-006870-f5w6fw6q 718 9 for for IN cord-006870-f5w6fw6q 718 10 individuals individual NNS cord-006870-f5w6fw6q 718 11 after after IN cord-006870-f5w6fw6q 718 12 pharmacotherapy pharmacotherapy NN cord-006870-f5w6fw6q 718 13 ( ( -LRB- cord-006870-f5w6fw6q 718 14 mean mean JJ cord-006870-f5w6fw6q 718 15 change change NN cord-006870-f5w6fw6q 718 16 [ [ -LRB- cord-006870-f5w6fw6q 718 17 MC MC NNP cord-006870-f5w6fw6q 718 18 ] ] -RRB- cord-006870-f5w6fw6q 718 19 -11.7 -11.7 NNP cord-006870-f5w6fw6q 718 20 , , , cord-006870-f5w6fw6q 718 21 95 95 CD cord-006870-f5w6fw6q 718 22 % % NN cord-006870-f5w6fw6q 718 23 confidence confidence NN cord-006870-f5w6fw6q 718 24 interval interval NN cord-006870-f5w6fw6q 718 25 [ [ -LRB- cord-006870-f5w6fw6q 718 26 CI CI NNP cord-006870-f5w6fw6q 718 27 ] ] -RRB- cord-006870-f5w6fw6q 718 28 : : : cord-006870-f5w6fw6q 719 1 -15.5 -15.5 NFP cord-006870-f5w6fw6q 719 2 to to IN cord-006870-f5w6fw6q 719 3 -8.0 -8.0 NN cord-006870-f5w6fw6q 719 4 ) ) -RRB- cord-006870-f5w6fw6q 719 5 and and CC cord-006870-f5w6fw6q 719 6 significant significant JJ cord-006870-f5w6fw6q 719 7 difference difference NN cord-006870-f5w6fw6q 719 8 in in IN cord-006870-f5w6fw6q 719 9 reduction reduction NN cord-006870-f5w6fw6q 719 10 of of IN cord-006870-f5w6fw6q 719 11 depression depression NN cord-006870-f5w6fw6q 719 12 scores score NNS cord-006870-f5w6fw6q 719 13 between between IN cord-006870-f5w6fw6q 719 14 medications medication NNS cord-006870-f5w6fw6q 719 15 and and CC cord-006870-f5w6fw6q 719 16 placebo placebo NN cord-006870-f5w6fw6q 719 17 in in IN cord-006870-f5w6fw6q 719 18 the the DT cord-006870-f5w6fw6q 719 19 pooled pool VBN cord-006870-f5w6fw6q 719 20 estimate estimate NN cord-006870-f5w6fw6q 719 21 ( ( -LRB- cord-006870-f5w6fw6q 719 22 standardized standardized JJ cord-006870-f5w6fw6q 719 23 mean mean JJ cord-006870-f5w6fw6q 719 24 difference difference NN cord-006870-f5w6fw6q 719 25 of of IN cord-006870-f5w6fw6q 719 26 four four CD cord-006870-f5w6fw6q 719 27 trials trial NNS cord-006870-f5w6fw6q 719 28 [ [ -LRB- cord-006870-f5w6fw6q 719 29 SMD SMD NNP cord-006870-f5w6fw6q 719 30 ] ] -RRB- cord-006870-f5w6fw6q 719 31 -0.4 -0.4 NNS cord-006870-f5w6fw6q 719 32 , , , cord-006870-f5w6fw6q 720 1 95 95 CD cord-006870-f5w6fw6q 720 2 % % NN cord-006870-f5w6fw6q 720 3 CI ci NN cord-006870-f5w6fw6q 720 4 : : : cord-006870-f5w6fw6q 720 5 -0.7 -0.7 NN cord-006870-f5w6fw6q 720 6 to to IN cord-006870-f5w6fw6q 720 7 -0.1 -0.1 CD cord-006870-f5w6fw6q 720 8 ) ) -RRB- cord-006870-f5w6fw6q 720 9 ; ; : cord-006870-f5w6fw6q 720 10 however however RB cord-006870-f5w6fw6q 720 11 only only RB cord-006870-f5w6fw6q 720 12 one one CD cord-006870-f5w6fw6q 720 13 of of IN cord-006870-f5w6fw6q 720 14 the the DT cord-006870-f5w6fw6q 720 15 four four CD cord-006870-f5w6fw6q 720 16 treatment treatment NN cord-006870-f5w6fw6q 720 17 - - HYPH cord-006870-f5w6fw6q 720 18 placebo placebo NN cord-006870-f5w6fw6q 720 19 studies study NNS cord-006870-f5w6fw6q 720 20 found find VBD cord-006870-f5w6fw6q 720 21 medications medication NNS cord-006870-f5w6fw6q 720 22 significantly significantly RB cord-006870-f5w6fw6q 720 23 reduce reduce VBP cord-006870-f5w6fw6q 720 24 depression depression NN cord-006870-f5w6fw6q 720 25 scores score NNS cord-006870-f5w6fw6q 720 26 more more JJR cord-006870-f5w6fw6q 720 27 than than IN cord-006870-f5w6fw6q 720 28 placebo placebo NN cord-006870-f5w6fw6q 720 29 . . . cord-006870-f5w6fw6q 721 1 This this DT cord-006870-f5w6fw6q 721 2 meta meta JJ cord-006870-f5w6fw6q 721 3 - - HYPH cord-006870-f5w6fw6q 721 4 analysis analysis NN cord-006870-f5w6fw6q 721 5 found find VBD cord-006870-f5w6fw6q 721 6 a a DT cord-006870-f5w6fw6q 721 7 significant significant JJ cord-006870-f5w6fw6q 721 8 benefit benefit NN cord-006870-f5w6fw6q 721 9 of of IN cord-006870-f5w6fw6q 721 10 pharmacotherapy pharmacotherapy NN cord-006870-f5w6fw6q 721 11 for for IN cord-006870-f5w6fw6q 721 12 treatment treatment NN cord-006870-f5w6fw6q 721 13 of of IN cord-006870-f5w6fw6q 721 14 depression depression NN cord-006870-f5w6fw6q 721 15 in in IN cord-006870-f5w6fw6q 721 16 patients patient NNS cord-006870-f5w6fw6q 721 17 with with IN cord-006870-f5w6fw6q 721 18 TBI TBI NNP cord-006870-f5w6fw6q 721 19 . . . cord-006870-f5w6fw6q 722 1 However however RB cord-006870-f5w6fw6q 722 2 , , , cord-006870-f5w6fw6q 722 3 there there EX cord-006870-f5w6fw6q 722 4 was be VBD cord-006870-f5w6fw6q 722 5 a a DT cord-006870-f5w6fw6q 722 6 high high JJ cord-006870-f5w6fw6q 722 7 degree degree NN cord-006870-f5w6fw6q 722 8 of of IN cord-006870-f5w6fw6q 722 9 bias bias NN cord-006870-f5w6fw6q 722 10 and and CC cord-006870-f5w6fw6q 722 11 heterogeneity heterogeneity NN cord-006870-f5w6fw6q 722 12 regarding regard VBG cord-006870-f5w6fw6q 722 13 TBI TBI NNP cord-006870-f5w6fw6q 722 14 severity severity NN cord-006870-f5w6fw6q 722 15 , , , cord-006870-f5w6fw6q 722 16 time time NN cord-006870-f5w6fw6q 722 17 since since IN cord-006870-f5w6fw6q 722 18 injury injury NN cord-006870-f5w6fw6q 722 19 , , , cord-006870-f5w6fw6q 722 20 depression depression NN cord-006870-f5w6fw6q 722 21 severity severity NN cord-006870-f5w6fw6q 722 22 , , , cord-006870-f5w6fw6q 722 23 and and CC cord-006870-f5w6fw6q 722 24 demographics demographic NNS cord-006870-f5w6fw6q 722 25 . . . cord-006870-f5w6fw6q 723 1 Larger large JJR cord-006870-f5w6fw6q 723 2 prospective prospective JJ cord-006870-f5w6fw6q 723 3 studies study NNS cord-006870-f5w6fw6q 723 4 on on IN cord-006870-f5w6fw6q 723 5 the the DT cord-006870-f5w6fw6q 723 6 impact impact NN cord-006870-f5w6fw6q 723 7 of of IN cord-006870-f5w6fw6q 723 8 anti anti JJ cord-006870-f5w6fw6q 723 9 - - NNS cord-006870-f5w6fw6q 723 10 depressants depressant NNS cord-006870-f5w6fw6q 723 11 on on IN cord-006870-f5w6fw6q 723 12 post post JJ cord-006870-f5w6fw6q 723 13 - - JJ cord-006870-f5w6fw6q 723 14 TBI tbi JJ cord-006870-f5w6fw6q 723 15 depression depression NN cord-006870-f5w6fw6q 723 16 are be VBP cord-006870-f5w6fw6q 723 17 warranted warrant VBN cord-006870-f5w6fw6q 723 18 to to TO cord-006870-f5w6fw6q 723 19 better better RB cord-006870-f5w6fw6q 723 20 understand understand VB cord-006870-f5w6fw6q 723 21 treatment treatment NN cord-006870-f5w6fw6q 723 22 effects effect NNS cord-006870-f5w6fw6q 723 23 and and CC cord-006870-f5w6fw6q 723 24 the the DT cord-006870-f5w6fw6q 723 25 relationship relationship NN cord-006870-f5w6fw6q 723 26 of of IN cord-006870-f5w6fw6q 723 27 post post JJ cord-006870-f5w6fw6q 723 28 - - JJ cord-006870-f5w6fw6q 723 29 TBI tbi JJ cord-006870-f5w6fw6q 723 30 depression depression NN cord-006870-f5w6fw6q 723 31 and and CC cord-006870-f5w6fw6q 723 32 outcome outcome NN cord-006870-f5w6fw6q 723 33 more more RBR cord-006870-f5w6fw6q 723 34 broadly broadly RB cord-006870-f5w6fw6q 723 35 . . . cord-006870-f5w6fw6q 724 1 Pleural Pleural NNP cord-006870-f5w6fw6q 724 2 effusion effusion NN cord-006870-f5w6fw6q 724 3 ( ( -LRB- cord-006870-f5w6fw6q 724 4 PE PE NNP cord-006870-f5w6fw6q 724 5 ) ) -RRB- cord-006870-f5w6fw6q 724 6 has have VBZ cord-006870-f5w6fw6q 724 7 been be VBN cord-006870-f5w6fw6q 724 8 reported report VBN cord-006870-f5w6fw6q 724 9 in in IN cord-006870-f5w6fw6q 724 10 62 62 CD cord-006870-f5w6fw6q 724 11 % % NN cord-006870-f5w6fw6q 724 12 of of IN cord-006870-f5w6fw6q 724 13 medical medical JJ cord-006870-f5w6fw6q 724 14 ICU ICU NNP cord-006870-f5w6fw6q 724 15 . . . cord-006870-f5w6fw6q 725 1 There there EX cord-006870-f5w6fw6q 725 2 is be VBZ cord-006870-f5w6fw6q 725 3 little little JJ cord-006870-f5w6fw6q 725 4 published publish VBN cord-006870-f5w6fw6q 725 5 data datum NNS cord-006870-f5w6fw6q 725 6 on on IN cord-006870-f5w6fw6q 725 7 the the DT cord-006870-f5w6fw6q 725 8 prevalence prevalence NN cord-006870-f5w6fw6q 725 9 and and CC cord-006870-f5w6fw6q 725 10 clinical clinical JJ cord-006870-f5w6fw6q 725 11 significance significance NN cord-006870-f5w6fw6q 725 12 of of IN cord-006870-f5w6fw6q 725 13 PE PE NNP cord-006870-f5w6fw6q 725 14 in in IN cord-006870-f5w6fw6q 725 15 mechanically mechanically RB cord-006870-f5w6fw6q 725 16 ventilated ventilate VBN cord-006870-f5w6fw6q 725 17 patients patient NNS cord-006870-f5w6fw6q 725 18 with with IN cord-006870-f5w6fw6q 725 19 traumatic traumatic JJ cord-006870-f5w6fw6q 725 20 brain brain NN cord-006870-f5w6fw6q 725 21 injury injury NN cord-006870-f5w6fw6q 725 22 . . . cord-006870-f5w6fw6q 726 1 Head Head NNP cord-006870-f5w6fw6q 726 2 injury injury NN cord-006870-f5w6fw6q 726 3 patients patient NNS cord-006870-f5w6fw6q 726 4 admitted admit VBD cord-006870-f5w6fw6q 726 5 to to IN cord-006870-f5w6fw6q 726 6 ICU ICU NNP cord-006870-f5w6fw6q 726 7 for for IN cord-006870-f5w6fw6q 726 8 mechanical mechanical JJ cord-006870-f5w6fw6q 726 9 ventilation ventilation NN cord-006870-f5w6fw6q 726 10 ( ( -LRB- cord-006870-f5w6fw6q 726 11 MV MV NNP cord-006870-f5w6fw6q 726 12 ) ) -RRB- cord-006870-f5w6fw6q 726 13 within within IN cord-006870-f5w6fw6q 726 14 48 48 CD cord-006870-f5w6fw6q 726 15 - - SYM cord-006870-f5w6fw6q 726 16 72 72 CD cord-006870-f5w6fw6q 726 17 hours hour NNS cord-006870-f5w6fw6q 726 18 and and CC cord-006870-f5w6fw6q 726 19 GCS GCS NNP cord-006870-f5w6fw6q 726 20 > > XX cord-006870-f5w6fw6q 727 1 5 5 CD cord-006870-f5w6fw6q 727 2 were be VBD cord-006870-f5w6fw6q 727 3 assessed assess VBN cord-006870-f5w6fw6q 727 4 for for IN cord-006870-f5w6fw6q 727 5 eligibility eligibility NN cord-006870-f5w6fw6q 727 6 . . . cord-006870-f5w6fw6q 728 1 Presence presence NN cord-006870-f5w6fw6q 728 2 of of IN cord-006870-f5w6fw6q 728 3 PE PE NNP cord-006870-f5w6fw6q 728 4 was be VBD cord-006870-f5w6fw6q 728 5 assessed assess VBN cord-006870-f5w6fw6q 728 6 by by IN cord-006870-f5w6fw6q 728 7 serial serial JJ cord-006870-f5w6fw6q 728 8 CXR CXR NNP cord-006870-f5w6fw6q 728 9 on on IN cord-006870-f5w6fw6q 728 10 daily daily JJ cord-006870-f5w6fw6q 728 11 basis basis NN cord-006870-f5w6fw6q 728 12 and and CC cord-006870-f5w6fw6q 728 13 volume volume NN cord-006870-f5w6fw6q 728 14 of of IN cord-006870-f5w6fw6q 728 15 effusion effusion NN cord-006870-f5w6fw6q 728 16 was be VBD cord-006870-f5w6fw6q 728 17 estimated estimate VBN cord-006870-f5w6fw6q 728 18 and and CC cord-006870-f5w6fw6q 728 19 recorded record VBN cord-006870-f5w6fw6q 728 20 . . . cord-006870-f5w6fw6q 729 1 In in IN cord-006870-f5w6fw6q 729 2 case case NN cord-006870-f5w6fw6q 729 3 there there EX cord-006870-f5w6fw6q 729 4 was be VBD cord-006870-f5w6fw6q 729 5 no no DT cord-006870-f5w6fw6q 729 6 evidence evidence NN cord-006870-f5w6fw6q 729 7 of of IN cord-006870-f5w6fw6q 729 8 PE PE NNP cord-006870-f5w6fw6q 729 9 on on IN cord-006870-f5w6fw6q 729 10 CXR CXR NNP cord-006870-f5w6fw6q 729 11 , , , cord-006870-f5w6fw6q 729 12 a a DT cord-006870-f5w6fw6q 729 13 bedside bedside NN cord-006870-f5w6fw6q 729 14 sonography sonography NN cord-006870-f5w6fw6q 729 15 in in IN cord-006870-f5w6fw6q 729 16 semi semi JJ cord-006870-f5w6fw6q 729 17 recumbent recumbent JJ cord-006870-f5w6fw6q 729 18 position position NN cord-006870-f5w6fw6q 729 19 was be VBD cord-006870-f5w6fw6q 729 20 done do VBN cord-006870-f5w6fw6q 729 21 within within IN cord-006870-f5w6fw6q 729 22 72 72 CD cord-006870-f5w6fw6q 729 23 h h NN cord-006870-f5w6fw6q 729 24 of of IN cord-006870-f5w6fw6q 729 25 ICU ICU NNP cord-006870-f5w6fw6q 729 26 admission admission NN cord-006870-f5w6fw6q 729 27 . . . cord-006870-f5w6fw6q 730 1 Pleural Pleural NNP cord-006870-f5w6fw6q 730 2 fluid fluid NN cord-006870-f5w6fw6q 730 3 volume volume NN cord-006870-f5w6fw6q 730 4 was be VBD cord-006870-f5w6fw6q 730 5 estimated estimate VBN cord-006870-f5w6fw6q 730 6 based base VBN cord-006870-f5w6fw6q 730 7 on on IN cord-006870-f5w6fw6q 730 8 4-point 4-point CD cord-006870-f5w6fw6q 730 9 classifications classification NNS cord-006870-f5w6fw6q 730 10 on on IN cord-006870-f5w6fw6q 730 11 sonography sonography NN cord-006870-f5w6fw6q 730 12 . . . cord-006870-f5w6fw6q 731 1 Details detail NNS cord-006870-f5w6fw6q 731 2 of of IN cord-006870-f5w6fw6q 731 3 mechanical mechanical JJ cord-006870-f5w6fw6q 731 4 ventilation ventilation NN cord-006870-f5w6fw6q 731 5 and and CC cord-006870-f5w6fw6q 731 6 ICU ICU NNP cord-006870-f5w6fw6q 731 7 management management NN cord-006870-f5w6fw6q 731 8 were be VBD cord-006870-f5w6fw6q 731 9 recorded record VBN cord-006870-f5w6fw6q 731 10 . . . cord-006870-f5w6fw6q 732 1 Successful successful JJ cord-006870-f5w6fw6q 732 2 weaning weaning NN cord-006870-f5w6fw6q 732 3 was be VBD cord-006870-f5w6fw6q 732 4 defined define VBN cord-006870-f5w6fw6q 732 5 as as IN cord-006870-f5w6fw6q 732 6 ability ability NN cord-006870-f5w6fw6q 732 7 to to TO cord-006870-f5w6fw6q 732 8 breath breath VB cord-006870-f5w6fw6q 732 9 spontaneously spontaneously RB cord-006870-f5w6fw6q 732 10 for for IN cord-006870-f5w6fw6q 732 11 48 48 CD cord-006870-f5w6fw6q 732 12 h. h. NNP cord-006870-f5w6fw6q 732 13 Primary primary JJ cord-006870-f5w6fw6q 732 14 aim aim NN cord-006870-f5w6fw6q 732 15 was be VBD cord-006870-f5w6fw6q 732 16 to to TO cord-006870-f5w6fw6q 732 17 observe observe VB cord-006870-f5w6fw6q 732 18 prevalence prevalence NN cord-006870-f5w6fw6q 732 19 of of IN cord-006870-f5w6fw6q 732 20 PE PE NNP cord-006870-f5w6fw6q 732 21 in in IN cord-006870-f5w6fw6q 732 22 MV MV NNP cord-006870-f5w6fw6q 732 23 head head NN cord-006870-f5w6fw6q 732 24 injured injure VBN cord-006870-f5w6fw6q 732 25 patients patient NNS cord-006870-f5w6fw6q 732 26 . . . cord-006870-f5w6fw6q 733 1 As as IN cord-006870-f5w6fw6q 733 2 secondary secondary JJ cord-006870-f5w6fw6q 733 3 measure measure NN cord-006870-f5w6fw6q 733 4 ; ; : cord-006870-f5w6fw6q 733 5 impact impact NN cord-006870-f5w6fw6q 733 6 of of IN cord-006870-f5w6fw6q 733 7 PE PE NNP cord-006870-f5w6fw6q 733 8 on on IN cord-006870-f5w6fw6q 733 9 duration duration NN cord-006870-f5w6fw6q 733 10 of of IN cord-006870-f5w6fw6q 733 11 MV MV NNP cord-006870-f5w6fw6q 733 12 , , , cord-006870-f5w6fw6q 733 13 weaning weaning NN cord-006870-f5w6fw6q 733 14 and and CC cord-006870-f5w6fw6q 733 15 length length NN cord-006870-f5w6fw6q 733 16 of of IN cord-006870-f5w6fw6q 733 17 ICU ICU NNP cord-006870-f5w6fw6q 733 18 stay stay NN cord-006870-f5w6fw6q 733 19 were be VBD cord-006870-f5w6fw6q 733 20 compared compare VBN cord-006870-f5w6fw6q 733 21 . . . cord-006870-f5w6fw6q 734 1 Study study NN cord-006870-f5w6fw6q 734 2 enrolled enrol VBD cord-006870-f5w6fw6q 734 3 90 90 CD cord-006870-f5w6fw6q 734 4 patients patient NNS cord-006870-f5w6fw6q 734 5 . . . cord-006870-f5w6fw6q 735 1 Three three CD cord-006870-f5w6fw6q 735 2 baseline baseline NN cord-006870-f5w6fw6q 736 1 CXR CXR NNP cord-006870-f5w6fw6q 736 2 showed show VBD cord-006870-f5w6fw6q 736 3 PE PE NNP cord-006870-f5w6fw6q 736 4 . . . cord-006870-f5w6fw6q 737 1 Total total NN cord-006870-f5w6fw6q 737 2 of of IN cord-006870-f5w6fw6q 737 3 27(30 27(30 CD cord-006870-f5w6fw6q 737 4 % % NN cord-006870-f5w6fw6q 737 5 ) ) -RRB- cord-006870-f5w6fw6q 737 6 patients patient NNS cord-006870-f5w6fw6q 737 7 developed develop VBD cord-006870-f5w6fw6q 737 8 PE PE NNP cord-006870-f5w6fw6q 737 9 in in IN cord-006870-f5w6fw6q 737 10 ICU ICU NNP cord-006870-f5w6fw6q 737 11 . . . cord-006870-f5w6fw6q 738 1 9 9 CD cord-006870-f5w6fw6q 738 2 patients patient NNS cord-006870-f5w6fw6q 738 3 had have VBD cord-006870-f5w6fw6q 738 4 evidence evidence NN cord-006870-f5w6fw6q 738 5 of of IN cord-006870-f5w6fw6q 738 6 PE PE NNP cord-006870-f5w6fw6q 738 7 on on IN cord-006870-f5w6fw6q 738 8 both both CC cord-006870-f5w6fw6q 738 9 CXR CXR NNP cord-006870-f5w6fw6q 738 10 and and CC cord-006870-f5w6fw6q 738 11 USG USG NNP cord-006870-f5w6fw6q 738 12 . . . cord-006870-f5w6fw6q 739 1 18 18 CD cord-006870-f5w6fw6q 739 2 patients patient NNS cord-006870-f5w6fw6q 739 3 had have VBD cord-006870-f5w6fw6q 739 4 only only RB cord-006870-f5w6fw6q 739 5 sonographic sonographic JJ cord-006870-f5w6fw6q 739 6 evidence evidence NN cord-006870-f5w6fw6q 739 7 of of IN cord-006870-f5w6fw6q 739 8 PE PE NNP cord-006870-f5w6fw6q 739 9 , , , cord-006870-f5w6fw6q 739 10 which which WDT cord-006870-f5w6fw6q 739 11 were be VBD cord-006870-f5w6fw6q 739 12 not not RB cord-006870-f5w6fw6q 739 13 detected detect VBN cord-006870-f5w6fw6q 739 14 on on IN cord-006870-f5w6fw6q 739 15 CXR CXR NNP cord-006870-f5w6fw6q 739 16 . . . cord-006870-f5w6fw6q 740 1 Significantly significantly RB cord-006870-f5w6fw6q 740 2 more more RBR cord-006870-f5w6fw6q 740 3 minimal minimal JJ cord-006870-f5w6fw6q 740 4 effusions effusion NNS cord-006870-f5w6fw6q 740 5 were be VBD cord-006870-f5w6fw6q 740 6 detected detect VBN cord-006870-f5w6fw6q 740 7 on on IN cord-006870-f5w6fw6q 740 8 sonography sonography NN cord-006870-f5w6fw6q 740 9 ( ( -LRB- cord-006870-f5w6fw6q 740 10 10/27 10/27 CD cord-006870-f5w6fw6q 740 11 , , , cord-006870-f5w6fw6q 740 12 p=0.03 p=0.03 NNP cord-006870-f5w6fw6q 740 13 ) ) -RRB- cord-006870-f5w6fw6q 740 14 . . . cord-006870-f5w6fw6q 741 1 Duration duration NN cord-006870-f5w6fw6q 741 2 of of IN cord-006870-f5w6fw6q 741 3 mechanical mechanical JJ cord-006870-f5w6fw6q 741 4 ventilation ventilation NN cord-006870-f5w6fw6q 741 5 and and CC cord-006870-f5w6fw6q 741 6 duration duration NN cord-006870-f5w6fw6q 741 7 of of IN cord-006870-f5w6fw6q 741 8 ICU ICU NNP cord-006870-f5w6fw6q 741 9 stay stay NN cord-006870-f5w6fw6q 741 10 were be VBD cord-006870-f5w6fw6q 741 11 significantly significantly RB cord-006870-f5w6fw6q 741 12 more more JJR cord-006870-f5w6fw6q 741 13 in in IN cord-006870-f5w6fw6q 741 14 patients patient NNS cord-006870-f5w6fw6q 741 15 with with IN cord-006870-f5w6fw6q 741 16 PE PE NNP cord-006870-f5w6fw6q 741 17 . . . cord-006870-f5w6fw6q 742 1 ( ( -LRB- cord-006870-f5w6fw6q 742 2 p= p= NNP cord-006870-f5w6fw6q 742 3 0.009 0.009 CD cord-006870-f5w6fw6q 742 4 , , , cord-006870-f5w6fw6q 742 5 Mann Mann NNP cord-006870-f5w6fw6q 742 6 Whitney Whitney NNP cord-006870-f5w6fw6q 742 7 rank rank NN cord-006870-f5w6fw6q 742 8 sum sum NN cord-006870-f5w6fw6q 742 9 test test NN cord-006870-f5w6fw6q 742 10 ) ) -RRB- cord-006870-f5w6fw6q 743 1 There there EX cord-006870-f5w6fw6q 743 2 was be VBD cord-006870-f5w6fw6q 743 3 no no DT cord-006870-f5w6fw6q 743 4 significance significance NN cord-006870-f5w6fw6q 743 5 difference difference NN cord-006870-f5w6fw6q 743 6 in in IN cord-006870-f5w6fw6q 743 7 duration duration NN cord-006870-f5w6fw6q 743 8 of of IN cord-006870-f5w6fw6q 743 9 weaning weaning NN cord-006870-f5w6fw6q 743 10 in in IN cord-006870-f5w6fw6q 743 11 patients patient NNS cord-006870-f5w6fw6q 743 12 with with IN cord-006870-f5w6fw6q 743 13 and and CC cord-006870-f5w6fw6q 743 14 without without IN cord-006870-f5w6fw6q 743 15 effusion effusion NN cord-006870-f5w6fw6q 743 16 ( ( -LRB- cord-006870-f5w6fw6q 743 17 2.9±2.2 2.9±2.2 CD cord-006870-f5w6fw6q 743 18 , , , cord-006870-f5w6fw6q 743 19 2.1±1.3 2.1±1.3 CD cord-006870-f5w6fw6q 743 20 , , , cord-006870-f5w6fw6q 743 21 p=0.084 p=0.084 NNP cord-006870-f5w6fw6q 743 22 ) ) -RRB- cord-006870-f5w6fw6q 743 23 . . . cord-006870-f5w6fw6q 744 1 Chest chest NN cord-006870-f5w6fw6q 744 2 ultrasonography ultrasonography NN cord-006870-f5w6fw6q 744 3 increased increase VBD cord-006870-f5w6fw6q 744 4 the the DT cord-006870-f5w6fw6q 744 5 detection detection NN cord-006870-f5w6fw6q 744 6 rate rate NN cord-006870-f5w6fw6q 744 7 of of IN cord-006870-f5w6fw6q 744 8 pleural pleural JJ cord-006870-f5w6fw6q 744 9 fluid fluid NN cord-006870-f5w6fw6q 744 10 . . . cord-006870-f5w6fw6q 745 1 Patients patient NNS cord-006870-f5w6fw6q 745 2 with with IN cord-006870-f5w6fw6q 745 3 PE PE NNP cord-006870-f5w6fw6q 745 4 had have VBD cord-006870-f5w6fw6q 745 5 longer long JJR cord-006870-f5w6fw6q 745 6 duration duration NN cord-006870-f5w6fw6q 745 7 of of IN cord-006870-f5w6fw6q 745 8 mechanical mechanical JJ cord-006870-f5w6fw6q 745 9 ventilation ventilation NN cord-006870-f5w6fw6q 745 10 . . . cord-006870-f5w6fw6q 746 1 Early early JJ cord-006870-f5w6fw6q 746 2 detection detection NN cord-006870-f5w6fw6q 746 3 may may MD cord-006870-f5w6fw6q 746 4 be be VB cord-006870-f5w6fw6q 746 5 associated associate VBN cord-006870-f5w6fw6q 746 6 with with IN cord-006870-f5w6fw6q 746 7 shorter short JJR cord-006870-f5w6fw6q 746 8 period period NN cord-006870-f5w6fw6q 746 9 of of IN cord-006870-f5w6fw6q 746 10 mechanical mechanical JJ cord-006870-f5w6fw6q 746 11 ventilation ventilation NN cord-006870-f5w6fw6q 746 12 and and CC cord-006870-f5w6fw6q 746 13 ICU ICU NNP cord-006870-f5w6fw6q 746 14 stay stay VBP cord-006870-f5w6fw6q 746 15 Spine Spine NNP cord-006870-f5w6fw6q 746 16 surgery surgery NN cord-006870-f5w6fw6q 746 17 can can MD cord-006870-f5w6fw6q 746 18 trigger trigger VB cord-006870-f5w6fw6q 746 19 a a DT cord-006870-f5w6fw6q 746 20 systemic systemic JJ cord-006870-f5w6fw6q 746 21 inflammatory inflammatory JJ cord-006870-f5w6fw6q 746 22 response response NN cord-006870-f5w6fw6q 746 23 syndrome syndrome NN cord-006870-f5w6fw6q 746 24 and and CC cord-006870-f5w6fw6q 746 25 lead lead VB cord-006870-f5w6fw6q 746 26 to to IN cord-006870-f5w6fw6q 746 27 hypotension hypotension NN cord-006870-f5w6fw6q 746 28 requiring require VBG cord-006870-f5w6fw6q 746 29 vasopressors vasopressor NNS cord-006870-f5w6fw6q 746 30 . . . cord-006870-f5w6fw6q 747 1 As as IN cord-006870-f5w6fw6q 747 2 sepsis sepsis NN cord-006870-f5w6fw6q 747 3 is be VBZ cord-006870-f5w6fw6q 747 4 a a DT cord-006870-f5w6fw6q 747 5 major major JJ cord-006870-f5w6fw6q 747 6 differential differential JJ cord-006870-f5w6fw6q 747 7 diagnosis diagnosis NN cord-006870-f5w6fw6q 747 8 in in IN cord-006870-f5w6fw6q 747 9 the the DT cord-006870-f5w6fw6q 747 10 post post JJ cord-006870-f5w6fw6q 747 11 - - JJ cord-006870-f5w6fw6q 747 12 operative operative JJ cord-006870-f5w6fw6q 747 13 period period NN cord-006870-f5w6fw6q 747 14 , , , cord-006870-f5w6fw6q 747 15 the the DT cord-006870-f5w6fw6q 747 16 objective objective NN cord-006870-f5w6fw6q 747 17 of of IN cord-006870-f5w6fw6q 747 18 this this DT cord-006870-f5w6fw6q 747 19 study study NN cord-006870-f5w6fw6q 747 20 is be VBZ cord-006870-f5w6fw6q 747 21 to to TO cord-006870-f5w6fw6q 747 22 understand understand VB cord-006870-f5w6fw6q 747 23 the the DT cord-006870-f5w6fw6q 747 24 prevalence prevalence NN cord-006870-f5w6fw6q 747 25 of of IN cord-006870-f5w6fw6q 747 26 a a DT cord-006870-f5w6fw6q 747 27 true true JJ cord-006870-f5w6fw6q 747 28 systemic systemic JJ cord-006870-f5w6fw6q 747 29 infection infection NN cord-006870-f5w6fw6q 747 30 in in IN cord-006870-f5w6fw6q 747 31 this this DT cord-006870-f5w6fw6q 747 32 setting setting NN cord-006870-f5w6fw6q 747 33 . . . cord-006870-f5w6fw6q 748 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 748 2 review review NN cord-006870-f5w6fw6q 748 3 of of IN cord-006870-f5w6fw6q 748 4 all all DT cord-006870-f5w6fw6q 748 5 consecutive consecutive JJ cord-006870-f5w6fw6q 748 6 adults adult NNS cord-006870-f5w6fw6q 748 7 with with IN cord-006870-f5w6fw6q 748 8 post post JJ cord-006870-f5w6fw6q 748 9 - - JJ cord-006870-f5w6fw6q 748 10 operative operative JJ cord-006870-f5w6fw6q 748 11 shock shock NN cord-006870-f5w6fw6q 748 12 requiring require VBG cord-006870-f5w6fw6q 748 13 vasopressors vasopressor NNS cord-006870-f5w6fw6q 748 14 following follow VBG cord-006870-f5w6fw6q 748 15 spine spine NN cord-006870-f5w6fw6q 748 16 surgery surgery NN cord-006870-f5w6fw6q 748 17 in in IN cord-006870-f5w6fw6q 748 18 an an DT cord-006870-f5w6fw6q 748 19 academic academic JJ cord-006870-f5w6fw6q 748 20 tertiary tertiary JJ cord-006870-f5w6fw6q 748 21 medical medical JJ cord-006870-f5w6fw6q 748 22 center center NN cord-006870-f5w6fw6q 748 23 . . . cord-006870-f5w6fw6q 749 1 A a DT cord-006870-f5w6fw6q 749 2 total total NN cord-006870-f5w6fw6q 749 3 of of IN cord-006870-f5w6fw6q 749 4 43 43 CD cord-006870-f5w6fw6q 749 5 patients patient NNS cord-006870-f5w6fw6q 749 6 , , , cord-006870-f5w6fw6q 749 7 median median JJ cord-006870-f5w6fw6q 749 8 age age NN cord-006870-f5w6fw6q 749 9 69 69 CD cord-006870-f5w6fw6q 749 10 years year NNS cord-006870-f5w6fw6q 750 1 ( ( -LRB- cord-006870-f5w6fw6q 750 2 IQR IQR NNP cord-006870-f5w6fw6q 750 3 57 57 CD cord-006870-f5w6fw6q 750 4 - - SYM cord-006870-f5w6fw6q 750 5 74 74 CD cord-006870-f5w6fw6q 750 6 ) ) -RRB- cord-006870-f5w6fw6q 750 7 , , , cord-006870-f5w6fw6q 750 8 were be VBD cord-006870-f5w6fw6q 750 9 included include VBN cord-006870-f5w6fw6q 750 10 in in IN cord-006870-f5w6fw6q 750 11 the the DT cord-006870-f5w6fw6q 750 12 final final JJ cord-006870-f5w6fw6q 750 13 analysis analysis NN cord-006870-f5w6fw6q 750 14 . . . cord-006870-f5w6fw6q 751 1 Comorbidities comorbiditie NNS cord-006870-f5w6fw6q 751 2 included include VBD cord-006870-f5w6fw6q 751 3 a a DT cord-006870-f5w6fw6q 751 4 median median JJ cord-006870-f5w6fw6q 751 5 BMI bmi NN cord-006870-f5w6fw6q 751 6 of of IN cord-006870-f5w6fw6q 751 7 28 28 CD cord-006870-f5w6fw6q 751 8 ( ( -LRB- cord-006870-f5w6fw6q 751 9 IQR IQR NNP cord-006870-f5w6fw6q 751 10 23 23 CD cord-006870-f5w6fw6q 751 11 - - SYM cord-006870-f5w6fw6q 751 12 33 33 CD cord-006870-f5w6fw6q 751 13 ) ) -RRB- cord-006870-f5w6fw6q 751 14 , , , cord-006870-f5w6fw6q 751 15 coronary coronary JJ cord-006870-f5w6fw6q 751 16 artery artery NN cord-006870-f5w6fw6q 751 17 disease disease NN cord-006870-f5w6fw6q 751 18 ( ( -LRB- cord-006870-f5w6fw6q 751 19 28 28 CD cord-006870-f5w6fw6q 751 20 % % NN cord-006870-f5w6fw6q 751 21 ) ) -RRB- cord-006870-f5w6fw6q 751 22 and and CC cord-006870-f5w6fw6q 751 23 diabetes diabetes NN cord-006870-f5w6fw6q 751 24 mellitus mellitus NN cord-006870-f5w6fw6q 751 25 ( ( -LRB- cord-006870-f5w6fw6q 751 26 16 16 CD cord-006870-f5w6fw6q 751 27 % % NN cord-006870-f5w6fw6q 751 28 ) ) -RRB- cord-006870-f5w6fw6q 751 29 . . . cord-006870-f5w6fw6q 752 1 Median median JJ cord-006870-f5w6fw6q 752 2 estimated estimate VBN cord-006870-f5w6fw6q 752 3 blood blood NN cord-006870-f5w6fw6q 752 4 loss loss NN cord-006870-f5w6fw6q 752 5 was be VBD cord-006870-f5w6fw6q 752 6 1200 1200 CD cord-006870-f5w6fw6q 752 7 cc cc NN cord-006870-f5w6fw6q 752 8 ( ( -LRB- cord-006870-f5w6fw6q 752 9 IQR IQR NNP cord-006870-f5w6fw6q 752 10 450 450 CD cord-006870-f5w6fw6q 752 11 to to IN cord-006870-f5w6fw6q 752 12 2150 2150 CD cord-006870-f5w6fw6q 752 13 cc cc NN cord-006870-f5w6fw6q 752 14 ) ) -RRB- cord-006870-f5w6fw6q 752 15 . . . cord-006870-f5w6fw6q 753 1 Circulatory circulatory JJ cord-006870-f5w6fw6q 753 2 volume volume NN cord-006870-f5w6fw6q 753 3 was be VBD cord-006870-f5w6fw6q 753 4 adequately adequately RB cord-006870-f5w6fw6q 753 5 replaced replace VBN cord-006870-f5w6fw6q 753 6 in in IN cord-006870-f5w6fw6q 753 7 a a DT cord-006870-f5w6fw6q 753 8 total total NN cord-006870-f5w6fw6q 753 9 of of IN cord-006870-f5w6fw6q 753 10 72 72 CD cord-006870-f5w6fw6q 753 11 % % NN cord-006870-f5w6fw6q 753 12 patients patient NNS cord-006870-f5w6fw6q 753 13 within within IN cord-006870-f5w6fw6q 753 14 6 6 CD cord-006870-f5w6fw6q 753 15 hours hour NNS cord-006870-f5w6fw6q 753 16 post post NN cord-006870-f5w6fw6q 753 17 - - NN cord-006870-f5w6fw6q 753 18 op op NN cord-006870-f5w6fw6q 753 19 . . . cord-006870-f5w6fw6q 754 1 All all DT cord-006870-f5w6fw6q 754 2 patients patient NNS cord-006870-f5w6fw6q 754 3 received receive VBD cord-006870-f5w6fw6q 754 4 crystalloids crystalloid NNS cord-006870-f5w6fw6q 754 5 , , , cord-006870-f5w6fw6q 754 6 and and CC cord-006870-f5w6fw6q 754 7 an an DT cord-006870-f5w6fw6q 754 8 additional additional JJ cord-006870-f5w6fw6q 754 9 42 42 CD cord-006870-f5w6fw6q 754 10 % % NN cord-006870-f5w6fw6q 754 11 received receive VBD cord-006870-f5w6fw6q 754 12 multiple multiple JJ cord-006870-f5w6fw6q 754 13 ( ( -LRB- cord-006870-f5w6fw6q 754 14 > > NFP cord-006870-f5w6fw6q 754 15 4 4 CD cord-006870-f5w6fw6q 754 16 ) ) -RRB- cord-006870-f5w6fw6q 754 17 units unit NNS cord-006870-f5w6fw6q 754 18 of of IN cord-006870-f5w6fw6q 754 19 PRBCs prbc NNS cord-006870-f5w6fw6q 754 20 transfusion transfusion NN cord-006870-f5w6fw6q 754 21 . . . cord-006870-f5w6fw6q 755 1 Adequate adequate JJ cord-006870-f5w6fw6q 755 2 urine urine NN cord-006870-f5w6fw6q 755 3 output output NN cord-006870-f5w6fw6q 755 4 was be VBD cord-006870-f5w6fw6q 755 5 confirmed confirm VBN cord-006870-f5w6fw6q 755 6 in in IN cord-006870-f5w6fw6q 755 7 42 42 CD cord-006870-f5w6fw6q 755 8 ( ( -LRB- cord-006870-f5w6fw6q 755 9 98 98 CD cord-006870-f5w6fw6q 755 10 % % NN cord-006870-f5w6fw6q 755 11 ) ) -RRB- cord-006870-f5w6fw6q 755 12 of of IN cord-006870-f5w6fw6q 755 13 the the DT cord-006870-f5w6fw6q 755 14 patients patient NNS cord-006870-f5w6fw6q 755 15 . . . cord-006870-f5w6fw6q 756 1 The the DT cord-006870-f5w6fw6q 756 2 maximum maximum JJ cord-006870-f5w6fw6q 756 3 median median JJ cord-006870-f5w6fw6q 756 4 rate rate NN cord-006870-f5w6fw6q 756 5 and and CC cord-006870-f5w6fw6q 756 6 duration duration NN cord-006870-f5w6fw6q 756 7 of of IN cord-006870-f5w6fw6q 756 8 each each DT cord-006870-f5w6fw6q 756 9 vasopressor vasopressor NN cord-006870-f5w6fw6q 756 10 infusion infusion NN cord-006870-f5w6fw6q 756 11 was be VBD cord-006870-f5w6fw6q 756 12 as as IN cord-006870-f5w6fw6q 756 13 follows follow VBZ cord-006870-f5w6fw6q 756 14 : : : cord-006870-f5w6fw6q 757 1 phenylephrine phenylephrine NNP cord-006870-f5w6fw6q 757 2 100 100 CD cord-006870-f5w6fw6q 757 3 mcg mcg NNP cord-006870-f5w6fw6q 757 4 / / SYM cord-006870-f5w6fw6q 757 5 min min NN cord-006870-f5w6fw6q 758 1 ( ( -LRB- cord-006870-f5w6fw6q 758 2 IQR IQR NNP cord-006870-f5w6fw6q 758 3 60 60 CD cord-006870-f5w6fw6q 758 4 - - SYM cord-006870-f5w6fw6q 758 5 150 150 CD cord-006870-f5w6fw6q 758 6 , , , cord-006870-f5w6fw6q 758 7 n n NN cord-006870-f5w6fw6q 758 8 = = SYM cord-006870-f5w6fw6q 758 9 39 39 CD cord-006870-f5w6fw6q 758 10 ) ) -RRB- cord-006870-f5w6fw6q 758 11 , , , cord-006870-f5w6fw6q 758 12 21 21 CD cord-006870-f5w6fw6q 758 13 hours hour NNS cord-006870-f5w6fw6q 759 1 ( ( -LRB- cord-006870-f5w6fw6q 759 2 IQR IQR NNP cord-006870-f5w6fw6q 759 3 12 12 CD cord-006870-f5w6fw6q 759 4 - - SYM cord-006870-f5w6fw6q 759 5 46 46 CD cord-006870-f5w6fw6q 759 6 ) ) -RRB- cord-006870-f5w6fw6q 759 7 , , . cord-006870-f5w6fw6q 760 1 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 760 2 40 40 CD cord-006870-f5w6fw6q 760 3 mcg mcg NNP cord-006870-f5w6fw6q 760 4 / / SYM cord-006870-f5w6fw6q 760 5 min min NN cord-006870-f5w6fw6q 761 1 ( ( -LRB- cord-006870-f5w6fw6q 761 2 IQR IQR NNP cord-006870-f5w6fw6q 761 3 20 20 CD cord-006870-f5w6fw6q 761 4 - - SYM cord-006870-f5w6fw6q 761 5 95 95 CD cord-006870-f5w6fw6q 761 6 , , , cord-006870-f5w6fw6q 761 7 n n NN cord-006870-f5w6fw6q 761 8 = = SYM cord-006870-f5w6fw6q 761 9 13 13 CD cord-006870-f5w6fw6q 761 10 ) ) -RRB- cord-006870-f5w6fw6q 761 11 , , , cord-006870-f5w6fw6q 761 12 16 16 CD cord-006870-f5w6fw6q 761 13 hours hour NNS cord-006870-f5w6fw6q 761 14 ( ( -LRB- cord-006870-f5w6fw6q 761 15 IQR IQR NNP cord-006870-f5w6fw6q 761 16 8 8 CD cord-006870-f5w6fw6q 761 17 - - SYM cord-006870-f5w6fw6q 761 18 62 62 CD cord-006870-f5w6fw6q 761 19 ) ) -RRB- cord-006870-f5w6fw6q 761 20 , , , cord-006870-f5w6fw6q 761 21 epinephrine epinephrine NN cord-006870-f5w6fw6q 761 22 10 10 CD cord-006870-f5w6fw6q 761 23 mcg mcg NNP cord-006870-f5w6fw6q 761 24 / / SYM cord-006870-f5w6fw6q 761 25 min min NN cord-006870-f5w6fw6q 762 1 ( ( -LRB- cord-006870-f5w6fw6q 762 2 IQR IQR NNP cord-006870-f5w6fw6q 762 3 10 10 CD cord-006870-f5w6fw6q 762 4 - - SYM cord-006870-f5w6fw6q 762 5 50 50 CD cord-006870-f5w6fw6q 762 6 , , , cord-006870-f5w6fw6q 762 7 n n NN cord-006870-f5w6fw6q 762 8 = = SYM cord-006870-f5w6fw6q 762 9 3 3 CD cord-006870-f5w6fw6q 762 10 ) ) -RRB- cord-006870-f5w6fw6q 762 11 , , , cord-006870-f5w6fw6q 762 12 12 12 CD cord-006870-f5w6fw6q 762 13 hours hour NNS cord-006870-f5w6fw6q 763 1 ( ( -LRB- cord-006870-f5w6fw6q 763 2 IQR IQR NNP cord-006870-f5w6fw6q 763 3 8 8 CD cord-006870-f5w6fw6q 763 4 - - SYM cord-006870-f5w6fw6q 763 5 16 16 CD cord-006870-f5w6fw6q 763 6 ) ) -RRB- cord-006870-f5w6fw6q 763 7 and and CC cord-006870-f5w6fw6q 763 8 vasopressin vasopressin NN cord-006870-f5w6fw6q 763 9 0.04 0.04 CD cord-006870-f5w6fw6q 763 10 units unit NNS cord-006870-f5w6fw6q 763 11 / / SYM cord-006870-f5w6fw6q 763 12 min min NN cord-006870-f5w6fw6q 763 13 , , , cord-006870-f5w6fw6q 763 14 23 23 CD cord-006870-f5w6fw6q 763 15 hours hour NNS cord-006870-f5w6fw6q 763 16 ( ( -LRB- cord-006870-f5w6fw6q 763 17 4 4 CD cord-006870-f5w6fw6q 763 18 - - SYM cord-006870-f5w6fw6q 763 19 31 31 CD cord-006870-f5w6fw6q 763 20 , , , cord-006870-f5w6fw6q 763 21 n n NN cord-006870-f5w6fw6q 763 22 = = SYM cord-006870-f5w6fw6q 763 23 3 3 CD cord-006870-f5w6fw6q 763 24 ) ) -RRB- cord-006870-f5w6fw6q 763 25 . . . cord-006870-f5w6fw6q 764 1 Of of IN cord-006870-f5w6fw6q 764 2 the the DT cord-006870-f5w6fw6q 764 3 43 43 CD cord-006870-f5w6fw6q 764 4 patients patient NNS cord-006870-f5w6fw6q 764 5 , , , cord-006870-f5w6fw6q 764 6 34 34 CD cord-006870-f5w6fw6q 764 7 ( ( -LRB- cord-006870-f5w6fw6q 764 8 79 79 CD cord-006870-f5w6fw6q 764 9 % % NN cord-006870-f5w6fw6q 764 10 ) ) -RRB- cord-006870-f5w6fw6q 764 11 met meet VBD cord-006870-f5w6fw6q 764 12 at at IN cord-006870-f5w6fw6q 764 13 least least JJS cord-006870-f5w6fw6q 764 14 2 2 CD cord-006870-f5w6fw6q 764 15 SIRS SIRS NNP cord-006870-f5w6fw6q 764 16 criteria criterion NNS cord-006870-f5w6fw6q 764 17 . . . cord-006870-f5w6fw6q 765 1 Infection infection NN cord-006870-f5w6fw6q 765 2 was be VBD cord-006870-f5w6fw6q 765 3 confirmed confirm VBN cord-006870-f5w6fw6q 765 4 in in IN cord-006870-f5w6fw6q 765 5 a a DT cord-006870-f5w6fw6q 765 6 total total NN cord-006870-f5w6fw6q 765 7 of of IN cord-006870-f5w6fw6q 765 8 10 10 CD cord-006870-f5w6fw6q 765 9 patients patient NNS cord-006870-f5w6fw6q 765 10 ; ; : cord-006870-f5w6fw6q 765 11 positive positive JJ cord-006870-f5w6fw6q 765 12 respiratory respiratory JJ cord-006870-f5w6fw6q 765 13 or or CC cord-006870-f5w6fw6q 765 14 blood blood NN cord-006870-f5w6fw6q 765 15 cultures culture NNS cord-006870-f5w6fw6q 765 16 in in IN cord-006870-f5w6fw6q 765 17 7 7 CD cord-006870-f5w6fw6q 765 18 ( ( -LRB- cord-006870-f5w6fw6q 765 19 16 16 CD cord-006870-f5w6fw6q 765 20 % % NN cord-006870-f5w6fw6q 765 21 ) ) -RRB- cord-006870-f5w6fw6q 765 22 patients patient NNS cord-006870-f5w6fw6q 765 23 and and CC cord-006870-f5w6fw6q 765 24 positive positive JJ cord-006870-f5w6fw6q 765 25 urinalysis urinalysis NN cord-006870-f5w6fw6q 765 26 or or CC cord-006870-f5w6fw6q 765 27 urine urine NN cord-006870-f5w6fw6q 765 28 culture culture NN cord-006870-f5w6fw6q 765 29 in in IN cord-006870-f5w6fw6q 765 30 5 5 CD cord-006870-f5w6fw6q 765 31 ( ( -LRB- cord-006870-f5w6fw6q 765 32 12 12 CD cord-006870-f5w6fw6q 765 33 % % NN cord-006870-f5w6fw6q 765 34 ) ) -RRB- cord-006870-f5w6fw6q 765 35 . . . cord-006870-f5w6fw6q 766 1 Two two CD cord-006870-f5w6fw6q 766 2 patients patient NNS cord-006870-f5w6fw6q 766 3 ( ( -LRB- cord-006870-f5w6fw6q 766 4 5 5 CD cord-006870-f5w6fw6q 766 5 % % NN cord-006870-f5w6fw6q 766 6 ) ) -RRB- cord-006870-f5w6fw6q 766 7 were be VBD cord-006870-f5w6fw6q 766 8 diagnosed diagnose VBN cord-006870-f5w6fw6q 766 9 with with IN cord-006870-f5w6fw6q 766 10 myocardial myocardial JJ cord-006870-f5w6fw6q 766 11 infarction infarction NN cord-006870-f5w6fw6q 766 12 . . . cord-006870-f5w6fw6q 767 1 No no DT cord-006870-f5w6fw6q 767 2 patients patient NNS cord-006870-f5w6fw6q 767 3 had have VBD cord-006870-f5w6fw6q 767 4 pulmonary pulmonary JJ cord-006870-f5w6fw6q 767 5 embolism embolism NN cord-006870-f5w6fw6q 767 6 . . . cord-006870-f5w6fw6q 768 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 768 2 study study NN cord-006870-f5w6fw6q 768 3 suggests suggest VBZ cord-006870-f5w6fw6q 768 4 that that IN cord-006870-f5w6fw6q 768 5 the the DT cord-006870-f5w6fw6q 768 6 risk risk NN cord-006870-f5w6fw6q 768 7 of of IN cord-006870-f5w6fw6q 768 8 infection infection NN cord-006870-f5w6fw6q 768 9 and and CC cord-006870-f5w6fw6q 768 10 sepsis sepsis NN cord-006870-f5w6fw6q 768 11 in in IN cord-006870-f5w6fw6q 768 12 patients patient NNS cord-006870-f5w6fw6q 768 13 with with IN cord-006870-f5w6fw6q 768 14 persistent persistent JJ cord-006870-f5w6fw6q 768 15 shock shock NN cord-006870-f5w6fw6q 768 16 following follow VBG cord-006870-f5w6fw6q 768 17 spine spine NN cord-006870-f5w6fw6q 768 18 surgery surgery NN cord-006870-f5w6fw6q 768 19 is be VBZ cord-006870-f5w6fw6q 768 20 small small JJ cord-006870-f5w6fw6q 768 21 but but CC cord-006870-f5w6fw6q 768 22 not not RB cord-006870-f5w6fw6q 768 23 negligible negligible JJ cord-006870-f5w6fw6q 768 24 . . . cord-006870-f5w6fw6q 769 1 Larger large JJR cord-006870-f5w6fw6q 769 2 multicenter multicenter JJ cord-006870-f5w6fw6q 769 3 studies study NNS cord-006870-f5w6fw6q 769 4 are be VBP cord-006870-f5w6fw6q 769 5 needed need VBN cord-006870-f5w6fw6q 769 6 to to TO cord-006870-f5w6fw6q 769 7 confirm confirm VB cord-006870-f5w6fw6q 769 8 our -PRON- PRP$ cord-006870-f5w6fw6q 769 9 findings finding NNS cord-006870-f5w6fw6q 769 10 and and CC cord-006870-f5w6fw6q 769 11 to to TO cord-006870-f5w6fw6q 769 12 identify identify VB cord-006870-f5w6fw6q 769 13 the the DT cord-006870-f5w6fw6q 769 14 predictive predictive JJ cord-006870-f5w6fw6q 769 15 factors factor NNS cord-006870-f5w6fw6q 769 16 . . . cord-006870-f5w6fw6q 770 1 Ischemic ischemic JJ cord-006870-f5w6fw6q 770 2 and and CC cord-006870-f5w6fw6q 770 3 hyperemic hyperemic JJ cord-006870-f5w6fw6q 770 4 injuries injury NNS cord-006870-f5w6fw6q 770 5 may may MD cord-006870-f5w6fw6q 770 6 occur occur VB cord-006870-f5w6fw6q 770 7 unnoticed unnoticed JJ cord-006870-f5w6fw6q 770 8 after after IN cord-006870-f5w6fw6q 770 9 severe severe JJ cord-006870-f5w6fw6q 770 10 traumatic traumatic JJ cord-006870-f5w6fw6q 770 11 brain brain NN cord-006870-f5w6fw6q 770 12 injury injury NN cord-006870-f5w6fw6q 770 13 ( ( -LRB- cord-006870-f5w6fw6q 770 14 TBI TBI NNP cord-006870-f5w6fw6q 770 15 ) ) -RRB- cord-006870-f5w6fw6q 770 16 and and CC cord-006870-f5w6fw6q 770 17 contribute contribute VB cord-006870-f5w6fw6q 770 18 to to IN cord-006870-f5w6fw6q 770 19 additional additional JJ cord-006870-f5w6fw6q 770 20 brain brain NN cord-006870-f5w6fw6q 770 21 damage damage NN cord-006870-f5w6fw6q 770 22 . . . cord-006870-f5w6fw6q 771 1 Maintaining maintain VBG cord-006870-f5w6fw6q 771 2 an an DT cord-006870-f5w6fw6q 771 3 adequate adequate JJ cord-006870-f5w6fw6q 771 4 cerebral cerebral JJ cord-006870-f5w6fw6q 771 5 perfusion perfusion NN cord-006870-f5w6fw6q 771 6 is be VBZ cord-006870-f5w6fw6q 771 7 considered consider VBN cord-006870-f5w6fw6q 771 8 crucial crucial JJ cord-006870-f5w6fw6q 771 9 in in IN cord-006870-f5w6fw6q 771 10 preventing prevent VBG cord-006870-f5w6fw6q 771 11 such such JJ cord-006870-f5w6fw6q 771 12 injuries injury NNS cord-006870-f5w6fw6q 771 13 , , , cord-006870-f5w6fw6q 771 14 as as IN cord-006870-f5w6fw6q 771 15 deviations deviation NNS cord-006870-f5w6fw6q 771 16 from from IN cord-006870-f5w6fw6q 771 17 autoregulation autoregulation NN cord-006870-f5w6fw6q 771 18 - - HYPH cord-006870-f5w6fw6q 771 19 guided guide VBN cord-006870-f5w6fw6q 771 20 optimal optimal JJ cord-006870-f5w6fw6q 771 21 cerebral cerebral JJ cord-006870-f5w6fw6q 771 22 perfusion perfusion NN cord-006870-f5w6fw6q 771 23 pressure pressure NN cord-006870-f5w6fw6q 771 24 ( ( -LRB- cord-006870-f5w6fw6q 771 25 CPPopt CPPopt NNP cord-006870-f5w6fw6q 771 26 ) ) -RRB- cord-006870-f5w6fw6q 771 27 are be VBP cord-006870-f5w6fw6q 771 28 associated associate VBN cord-006870-f5w6fw6q 771 29 with with IN cord-006870-f5w6fw6q 771 30 greater great JJR cord-006870-f5w6fw6q 771 31 mortality mortality NN cord-006870-f5w6fw6q 771 32 and and CC cord-006870-f5w6fw6q 771 33 disability disability NN cord-006870-f5w6fw6q 771 34 . . . cord-006870-f5w6fw6q 772 1 This this DT cord-006870-f5w6fw6q 772 2 makes make VBZ cord-006870-f5w6fw6q 772 3 reliable reliable JJ cord-006870-f5w6fw6q 772 4 estimation estimation NN cord-006870-f5w6fw6q 772 5 of of IN cord-006870-f5w6fw6q 772 6 CPPopt CPPopt NNP cord-006870-f5w6fw6q 772 7 an an DT cord-006870-f5w6fw6q 772 8 interesting interesting JJ cord-006870-f5w6fw6q 772 9 diagnostic diagnostic JJ cord-006870-f5w6fw6q 772 10 and and CC cord-006870-f5w6fw6q 772 11 treatment treatment NN cord-006870-f5w6fw6q 772 12 tool tool NN cord-006870-f5w6fw6q 772 13 for for IN cord-006870-f5w6fw6q 772 14 monitoring monitoring NN cord-006870-f5w6fw6q 772 15 . . . cord-006870-f5w6fw6q 773 1 CPPopt CPPopt NNP cord-006870-f5w6fw6q 773 2 is be VBZ cord-006870-f5w6fw6q 773 3 defined define VBN cord-006870-f5w6fw6q 773 4 as as IN cord-006870-f5w6fw6q 773 5 the the DT cord-006870-f5w6fw6q 773 6 cerebral cerebral JJ cord-006870-f5w6fw6q 773 7 perfusion perfusion NN cord-006870-f5w6fw6q 773 8 pressure pressure NN cord-006870-f5w6fw6q 773 9 ( ( -LRB- cord-006870-f5w6fw6q 773 10 CPP CPP NNP cord-006870-f5w6fw6q 773 11 ) ) -RRB- cord-006870-f5w6fw6q 773 12 at at IN cord-006870-f5w6fw6q 773 13 which which WDT cord-006870-f5w6fw6q 773 14 the the DT cord-006870-f5w6fw6q 773 15 pressure pressure NN cord-006870-f5w6fw6q 773 16 reactivity reactivity NN cord-006870-f5w6fw6q 773 17 index index NN cord-006870-f5w6fw6q 773 18 ( ( -LRB- cord-006870-f5w6fw6q 773 19 PRx PRx NNP cord-006870-f5w6fw6q 773 20 ) ) -RRB- cord-006870-f5w6fw6q 773 21 is be VBZ cord-006870-f5w6fw6q 773 22 minimal minimal JJ cord-006870-f5w6fw6q 773 23 . . . cord-006870-f5w6fw6q 774 1 The the DT cord-006870-f5w6fw6q 774 2 leading leading JJ cord-006870-f5w6fw6q 774 3 method method NN cord-006870-f5w6fw6q 774 4 for for IN cord-006870-f5w6fw6q 774 5 estimating estimate VBG cord-006870-f5w6fw6q 774 6 CPPopt CPPopt NNP cord-006870-f5w6fw6q 774 7 automatically automatically RB cord-006870-f5w6fw6q 774 8 , , , cord-006870-f5w6fw6q 774 9 by by IN cord-006870-f5w6fw6q 774 10 Aries Aries NNP cord-006870-f5w6fw6q 774 11 et et NNP cord-006870-f5w6fw6q 774 12 al al NNP cord-006870-f5w6fw6q 774 13 . . . cord-006870-f5w6fw6q 775 1 ( ( -LRB- cord-006870-f5w6fw6q 775 2 2012 2012 CD cord-006870-f5w6fw6q 775 3 ) ) -RRB- cord-006870-f5w6fw6q 775 4 , , , cord-006870-f5w6fw6q 775 5 fits fit VBZ cord-006870-f5w6fw6q 775 6 a a DT cord-006870-f5w6fw6q 775 7 parabola parabola NN cord-006870-f5w6fw6q 775 8 to to IN cord-006870-f5w6fw6q 775 9 pairs pair NNS cord-006870-f5w6fw6q 775 10 of of IN cord-006870-f5w6fw6q 775 11 PRx PRx NNS cord-006870-f5w6fw6q 775 12 and and CC cord-006870-f5w6fw6q 775 13 CPP CPP NNP cord-006870-f5w6fw6q 775 14 data datum NNS cord-006870-f5w6fw6q 775 15 . . . cord-006870-f5w6fw6q 776 1 The the DT cord-006870-f5w6fw6q 776 2 method method NN cord-006870-f5w6fw6q 776 3 uses use VBZ cord-006870-f5w6fw6q 776 4 preset preset JJ cord-006870-f5w6fw6q 776 5 heuristics heuristic NNS cord-006870-f5w6fw6q 776 6 to to TO cord-006870-f5w6fw6q 776 7 reject reject VB cord-006870-f5w6fw6q 776 8 the the DT cord-006870-f5w6fw6q 776 9 fit fit NN cord-006870-f5w6fw6q 776 10 as as RB cord-006870-f5w6fw6q 776 11 unreliable unreliable JJ cord-006870-f5w6fw6q 776 12 , , , cord-006870-f5w6fw6q 776 13 namely namely RB cord-006870-f5w6fw6q 776 14 when when WRB cord-006870-f5w6fw6q 776 15 the the DT cord-006870-f5w6fw6q 776 16 parabola parabola NN cord-006870-f5w6fw6q 776 17 is be VBZ cord-006870-f5w6fw6q 776 18 too too RB cord-006870-f5w6fw6q 776 19 " " `` cord-006870-f5w6fw6q 776 20 shallow shallow JJ cord-006870-f5w6fw6q 776 21 " " '' cord-006870-f5w6fw6q 776 22 or or CC cord-006870-f5w6fw6q 776 23 does do VBZ cord-006870-f5w6fw6q 776 24 not not RB cord-006870-f5w6fw6q 776 25 cover cover VB cord-006870-f5w6fw6q 776 26 a a DT cord-006870-f5w6fw6q 776 27 certain certain JJ cord-006870-f5w6fw6q 776 28 CPP CPP NNP cord-006870-f5w6fw6q 776 29 range range NN cord-006870-f5w6fw6q 776 30 . . . cord-006870-f5w6fw6q 777 1 As as IN cord-006870-f5w6fw6q 777 2 a a DT cord-006870-f5w6fw6q 777 3 result result NN cord-006870-f5w6fw6q 777 4 , , , cord-006870-f5w6fw6q 777 5 the the DT cord-006870-f5w6fw6q 777 6 2012 2012 CD cord-006870-f5w6fw6q 777 7 CPPopt CPPopt NNP cord-006870-f5w6fw6q 777 8 estimates estimate NNS cord-006870-f5w6fw6q 777 9 could could MD cord-006870-f5w6fw6q 777 10 be be VB cord-006870-f5w6fw6q 777 11 generated generate VBN cord-006870-f5w6fw6q 777 12 only only RB cord-006870-f5w6fw6q 777 13 about about RB cord-006870-f5w6fw6q 777 14 50 50 CD cord-006870-f5w6fw6q 777 15 - - SYM cord-006870-f5w6fw6q 777 16 60 60 CD cord-006870-f5w6fw6q 777 17 % % NN cord-006870-f5w6fw6q 777 18 of of IN cord-006870-f5w6fw6q 777 19 the the DT cord-006870-f5w6fw6q 777 20 time time NN cord-006870-f5w6fw6q 777 21 . . . cord-006870-f5w6fw6q 778 1 Moreover moreover RB cord-006870-f5w6fw6q 778 2 , , , cord-006870-f5w6fw6q 778 3 the the DT cord-006870-f5w6fw6q 778 4 manually manually RB cord-006870-f5w6fw6q 778 5 set set VBN cord-006870-f5w6fw6q 778 6 heuristics heuristic NNS cord-006870-f5w6fw6q 778 7 potentially potentially RB cord-006870-f5w6fw6q 778 8 restrict restrict VBP cord-006870-f5w6fw6q 778 9 the the DT cord-006870-f5w6fw6q 778 10 generality generality NN cord-006870-f5w6fw6q 778 11 of of IN cord-006870-f5w6fw6q 778 12 the the DT cord-006870-f5w6fw6q 778 13 model model NN cord-006870-f5w6fw6q 778 14 . . . cord-006870-f5w6fw6q 779 1 Here here RB cord-006870-f5w6fw6q 779 2 , , , cord-006870-f5w6fw6q 779 3 we -PRON- PRP cord-006870-f5w6fw6q 779 4 propose propose VBP cord-006870-f5w6fw6q 779 5 an an DT cord-006870-f5w6fw6q 779 6 alternative alternative JJ cord-006870-f5w6fw6q 779 7 method method NN cord-006870-f5w6fw6q 779 8 based base VBN cord-006870-f5w6fw6q 779 9 on on IN cord-006870-f5w6fw6q 779 10 Bayesian bayesian JJ cord-006870-f5w6fw6q 779 11 inference inference NN cord-006870-f5w6fw6q 779 12 . . . cord-006870-f5w6fw6q 780 1 Treating treat VBG cord-006870-f5w6fw6q 780 2 PRx PRx NNS cord-006870-f5w6fw6q 780 3 at at IN cord-006870-f5w6fw6q 780 4 each each DT cord-006870-f5w6fw6q 780 5 time time NN cord-006870-f5w6fw6q 780 6 as as IN cord-006870-f5w6fw6q 780 7 a a DT cord-006870-f5w6fw6q 780 8 function function NN cord-006870-f5w6fw6q 780 9 of of IN cord-006870-f5w6fw6q 780 10 CPP CPP NNP cord-006870-f5w6fw6q 780 11 corrupted corrupt VBN cord-006870-f5w6fw6q 780 12 by by IN cord-006870-f5w6fw6q 780 13 noise noise NN cord-006870-f5w6fw6q 780 14 serves serve VBZ cord-006870-f5w6fw6q 780 15 as as IN cord-006870-f5w6fw6q 780 16 a a DT cord-006870-f5w6fw6q 780 17 " " `` cord-006870-f5w6fw6q 780 18 forward forward JJ cord-006870-f5w6fw6q 780 19 model model NN cord-006870-f5w6fw6q 780 20 " " '' cord-006870-f5w6fw6q 780 21 that that WDT cord-006870-f5w6fw6q 780 22 can can MD cord-006870-f5w6fw6q 780 23 be be VB cord-006870-f5w6fw6q 780 24 inverted invert VBN cord-006870-f5w6fw6q 780 25 to to TO cord-006870-f5w6fw6q 780 26 yield yield VB cord-006870-f5w6fw6q 780 27 , , , cord-006870-f5w6fw6q 780 28 for for IN cord-006870-f5w6fw6q 780 29 a a DT cord-006870-f5w6fw6q 780 30 given give VBN cord-006870-f5w6fw6q 780 31 data data NN cord-006870-f5w6fw6q 780 32 set set NN cord-006870-f5w6fw6q 780 33 , , , cord-006870-f5w6fw6q 780 34 a a DT cord-006870-f5w6fw6q 780 35 temporally temporally RB cord-006870-f5w6fw6q 780 36 evolving evolve VBG cord-006870-f5w6fw6q 780 37 posterior posterior JJ cord-006870-f5w6fw6q 780 38 probability probability NN cord-006870-f5w6fw6q 780 39 distribution distribution NN cord-006870-f5w6fw6q 780 40 over over IN cord-006870-f5w6fw6q 780 41 CPPopt CPPopt NNP cord-006870-f5w6fw6q 780 42 . . . cord-006870-f5w6fw6q 781 1 The the DT cord-006870-f5w6fw6q 781 2 mean mean NN cord-006870-f5w6fw6q 781 3 of of IN cord-006870-f5w6fw6q 781 4 this this DT cord-006870-f5w6fw6q 781 5 distribution distribution NN cord-006870-f5w6fw6q 781 6 is be VBZ cord-006870-f5w6fw6q 781 7 a a DT cord-006870-f5w6fw6q 781 8 Bayesian bayesian JJ cord-006870-f5w6fw6q 781 9 estimate estimate NN cord-006870-f5w6fw6q 781 10 of of IN cord-006870-f5w6fw6q 781 11 CPPopt CPPopt NNP cord-006870-f5w6fw6q 781 12 ; ; : cord-006870-f5w6fw6q 781 13 we -PRON- PRP cord-006870-f5w6fw6q 781 14 find find VBP cord-006870-f5w6fw6q 781 15 that that IN cord-006870-f5w6fw6q 781 16 these these DT cord-006870-f5w6fw6q 781 17 estimates estimate NNS cord-006870-f5w6fw6q 781 18 are be VBP cord-006870-f5w6fw6q 781 19 generally generally RB cord-006870-f5w6fw6q 781 20 consistent consistent JJ cord-006870-f5w6fw6q 781 21 with with IN cord-006870-f5w6fw6q 781 22 those those DT cord-006870-f5w6fw6q 781 23 obtained obtain VBN cord-006870-f5w6fw6q 781 24 from from IN cord-006870-f5w6fw6q 781 25 the the DT cord-006870-f5w6fw6q 781 26 classic classic JJ cord-006870-f5w6fw6q 781 27 method method NN cord-006870-f5w6fw6q 781 28 . . . cord-006870-f5w6fw6q 782 1 Importantly importantly RB cord-006870-f5w6fw6q 782 2 , , , cord-006870-f5w6fw6q 782 3 the the DT cord-006870-f5w6fw6q 782 4 width width NN cord-006870-f5w6fw6q 782 5 of of IN cord-006870-f5w6fw6q 782 6 the the DT cord-006870-f5w6fw6q 782 7 distribution distribution NN cord-006870-f5w6fw6q 782 8 at at IN cord-006870-f5w6fw6q 782 9 a a DT cord-006870-f5w6fw6q 782 10 given give VBN cord-006870-f5w6fw6q 782 11 time time NN cord-006870-f5w6fw6q 782 12 serves serve VBZ cord-006870-f5w6fw6q 782 13 as as IN cord-006870-f5w6fw6q 782 14 a a DT cord-006870-f5w6fw6q 782 15 metric metric NN cord-006870-f5w6fw6q 782 16 of of IN cord-006870-f5w6fw6q 782 17 uncertainty uncertainty NN cord-006870-f5w6fw6q 782 18 about about IN cord-006870-f5w6fw6q 782 19 CPPopt CPPopt NNP cord-006870-f5w6fw6q 782 20 estimation estimation NN cord-006870-f5w6fw6q 782 21 . . . cord-006870-f5w6fw6q 783 1 We -PRON- PRP cord-006870-f5w6fw6q 783 2 find find VBP cord-006870-f5w6fw6q 783 3 that that IN cord-006870-f5w6fw6q 783 4 this this DT cord-006870-f5w6fw6q 783 5 uncertainty uncertainty NN cord-006870-f5w6fw6q 783 6 tends tend VBZ cord-006870-f5w6fw6q 783 7 to to TO cord-006870-f5w6fw6q 783 8 be be VB cord-006870-f5w6fw6q 783 9 large large JJ cord-006870-f5w6fw6q 783 10 at at IN cord-006870-f5w6fw6q 783 11 time time NN cord-006870-f5w6fw6q 783 12 points point NNS cord-006870-f5w6fw6q 783 13 where where WRB cord-006870-f5w6fw6q 783 14 the the DT cord-006870-f5w6fw6q 783 15 classic classic JJ cord-006870-f5w6fw6q 783 16 method method NN cord-006870-f5w6fw6q 783 17 with with IN cord-006870-f5w6fw6q 783 18 preset preset JJ cord-006870-f5w6fw6q 783 19 heuristics heuristic NNS cord-006870-f5w6fw6q 783 20 rejects reject VBZ cord-006870-f5w6fw6q 783 21 the the DT cord-006870-f5w6fw6q 783 22 fitted fit VBN cord-006870-f5w6fw6q 783 23 parabola parabola NN cord-006870-f5w6fw6q 783 24 . . . cord-006870-f5w6fw6q 784 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 784 2 method method NN cord-006870-f5w6fw6q 784 3 makes make VBZ cord-006870-f5w6fw6q 784 4 manually manually RB cord-006870-f5w6fw6q 784 5 setting set VBG cord-006870-f5w6fw6q 784 6 rejection rejection NN cord-006870-f5w6fw6q 784 7 criteria criterion NNS cord-006870-f5w6fw6q 784 8 unnecessary unnecessary JJ cord-006870-f5w6fw6q 784 9 . . . cord-006870-f5w6fw6q 785 1 Bayesian bayesian JJ cord-006870-f5w6fw6q 785 2 estimation estimation NN cord-006870-f5w6fw6q 785 3 of of IN cord-006870-f5w6fw6q 785 4 CPPopt CPPopt NNP cord-006870-f5w6fw6q 785 5 holds hold VBZ cord-006870-f5w6fw6q 785 6 promise promise NN cord-006870-f5w6fw6q 785 7 as as IN cord-006870-f5w6fw6q 785 8 a a DT cord-006870-f5w6fw6q 785 9 tool tool NN cord-006870-f5w6fw6q 785 10 for for IN cord-006870-f5w6fw6q 785 11 providing provide VBG cord-006870-f5w6fw6q 785 12 additional additional JJ cord-006870-f5w6fw6q 785 13 decision decision NN cord-006870-f5w6fw6q 785 14 support support NN cord-006870-f5w6fw6q 785 15 in in IN cord-006870-f5w6fw6q 785 16 the the DT cord-006870-f5w6fw6q 785 17 care care NN cord-006870-f5w6fw6q 785 18 of of IN cord-006870-f5w6fw6q 785 19 individual individual JJ cord-006870-f5w6fw6q 785 20 TBI TBI NNP cord-006870-f5w6fw6q 785 21 patients patient NNS cord-006870-f5w6fw6q 785 22 . . . cord-006870-f5w6fw6q 786 1 Quantitative quantitative JJ cord-006870-f5w6fw6q 786 2 parameters parameter NNS cord-006870-f5w6fw6q 786 3 derived derive VBN cord-006870-f5w6fw6q 786 4 from from IN cord-006870-f5w6fw6q 786 5 continuous continuous JJ cord-006870-f5w6fw6q 786 6 EEG EEG NNP cord-006870-f5w6fw6q 786 7 ( ( -LRB- cord-006870-f5w6fw6q 786 8 cEEG ceeg JJ cord-006870-f5w6fw6q 786 9 ) ) -RRB- cord-006870-f5w6fw6q 786 10 have have VBP cord-006870-f5w6fw6q 786 11 been be VBN cord-006870-f5w6fw6q 786 12 useful useful JJ cord-006870-f5w6fw6q 786 13 to to TO cord-006870-f5w6fw6q 786 14 understand understand VB cord-006870-f5w6fw6q 786 15 evolution evolution NN cord-006870-f5w6fw6q 786 16 of of IN cord-006870-f5w6fw6q 786 17 traumatic traumatic JJ cord-006870-f5w6fw6q 786 18 brain brain NN cord-006870-f5w6fw6q 786 19 injury injury NN cord-006870-f5w6fw6q 786 20 ( ( -LRB- cord-006870-f5w6fw6q 786 21 TBI TBI NNP cord-006870-f5w6fw6q 786 22 ) ) -RRB- cord-006870-f5w6fw6q 786 23 and and CC cord-006870-f5w6fw6q 786 24 the the DT cord-006870-f5w6fw6q 786 25 impact impact NN cord-006870-f5w6fw6q 786 26 on on IN cord-006870-f5w6fw6q 786 27 regional regional JJ cord-006870-f5w6fw6q 786 28 networks network NNS cord-006870-f5w6fw6q 786 29 . . . cord-006870-f5w6fw6q 787 1 These these DT cord-006870-f5w6fw6q 787 2 parameters parameter NNS cord-006870-f5w6fw6q 787 3 are be VBP cord-006870-f5w6fw6q 787 4 often often RB cord-006870-f5w6fw6q 787 5 interrogated interrogate VBN cord-006870-f5w6fw6q 787 6 at at IN cord-006870-f5w6fw6q 787 7 a a DT cord-006870-f5w6fw6q 787 8 global global JJ cord-006870-f5w6fw6q 787 9 level level NN cord-006870-f5w6fw6q 787 10 rather rather RB cord-006870-f5w6fw6q 787 11 than than IN cord-006870-f5w6fw6q 787 12 region region NN cord-006870-f5w6fw6q 787 13 - - HYPH cord-006870-f5w6fw6q 787 14 specific specific JJ cord-006870-f5w6fw6q 787 15 . . . cord-006870-f5w6fw6q 788 1 The the DT cord-006870-f5w6fw6q 788 2 regional regional JJ cord-006870-f5w6fw6q 788 3 evaluation evaluation NN cord-006870-f5w6fw6q 788 4 of of IN cord-006870-f5w6fw6q 788 5 quantitative quantitative JJ cord-006870-f5w6fw6q 788 6 EEG EEG NNP cord-006870-f5w6fw6q 788 7 parameters parameter NNS cord-006870-f5w6fw6q 788 8 may may MD cord-006870-f5w6fw6q 788 9 provide provide VB cord-006870-f5w6fw6q 788 10 an an DT cord-006870-f5w6fw6q 788 11 objective objective JJ cord-006870-f5w6fw6q 788 12 assessment assessment NN cord-006870-f5w6fw6q 788 13 of of IN cord-006870-f5w6fw6q 788 14 regional regional JJ cord-006870-f5w6fw6q 788 15 network network NN cord-006870-f5w6fw6q 788 16 function function NN cord-006870-f5w6fw6q 788 17 , , , cord-006870-f5w6fw6q 788 18 and and CC cord-006870-f5w6fw6q 788 19 be be VB cord-006870-f5w6fw6q 788 20 of of IN cord-006870-f5w6fw6q 788 21 predictive predictive JJ cord-006870-f5w6fw6q 788 22 value value NN cord-006870-f5w6fw6q 788 23 for for IN cord-006870-f5w6fw6q 788 24 prognostication prognostication NN cord-006870-f5w6fw6q 788 25 Continuous Continuous NNP cord-006870-f5w6fw6q 788 26 EEG EEG NNP cord-006870-f5w6fw6q 788 27 was be VBD cord-006870-f5w6fw6q 788 28 performed perform VBN cord-006870-f5w6fw6q 788 29 in in IN cord-006870-f5w6fw6q 788 30 54 54 CD cord-006870-f5w6fw6q 788 31 patients patient NNS cord-006870-f5w6fw6q 788 32 with with IN cord-006870-f5w6fw6q 788 33 TBI TBI NNP cord-006870-f5w6fw6q 788 34 , , , cord-006870-f5w6fw6q 788 35 and and CC cord-006870-f5w6fw6q 788 36 MRI MRI NNP cord-006870-f5w6fw6q 788 37 imaging imaging NN cord-006870-f5w6fw6q 788 38 was be VBD cord-006870-f5w6fw6q 788 39 obtained obtain VBN cord-006870-f5w6fw6q 788 40 during during IN cord-006870-f5w6fw6q 788 41 acute acute JJ cord-006870-f5w6fw6q 788 42 and and CC cord-006870-f5w6fw6q 788 43 chronic chronic JJ cord-006870-f5w6fw6q 788 44 time time NN cord-006870-f5w6fw6q 788 45 points point NNS cord-006870-f5w6fw6q 788 46 post post NN cord-006870-f5w6fw6q 788 47 injury injury NN cord-006870-f5w6fw6q 788 48 ( ( -LRB- cord-006870-f5w6fw6q 788 49 within within IN cord-006870-f5w6fw6q 788 50 30 30 CD cord-006870-f5w6fw6q 788 51 days day NNS cord-006870-f5w6fw6q 788 52 and and CC cord-006870-f5w6fw6q 788 53 6 6 CD cord-006870-f5w6fw6q 788 54 months month NNS cord-006870-f5w6fw6q 788 55 , , , cord-006870-f5w6fw6q 788 56 respectively respectively RB cord-006870-f5w6fw6q 788 57 ) ) -RRB- cord-006870-f5w6fw6q 788 58 . . . cord-006870-f5w6fw6q 789 1 The the DT cord-006870-f5w6fw6q 789 2 Extended Extended NNP cord-006870-f5w6fw6q 789 3 Glasgow Glasgow NNP cord-006870-f5w6fw6q 789 4 Outcome outcome NN cord-006870-f5w6fw6q 789 5 Scale scale NN cord-006870-f5w6fw6q 789 6 ( ( -LRB- cord-006870-f5w6fw6q 789 7 GOSE GOSE NNP cord-006870-f5w6fw6q 789 8 ) ) -RRB- cord-006870-f5w6fw6q 789 9 assessed assess VBD cord-006870-f5w6fw6q 789 10 clinical clinical JJ cord-006870-f5w6fw6q 789 11 recovery recovery NN cord-006870-f5w6fw6q 789 12 at at IN cord-006870-f5w6fw6q 789 13 6 6 CD cord-006870-f5w6fw6q 789 14 months month NNS cord-006870-f5w6fw6q 789 15 , , , cord-006870-f5w6fw6q 789 16 with with IN cord-006870-f5w6fw6q 789 17 good good JJ cord-006870-f5w6fw6q 789 18 recovery recovery NN cord-006870-f5w6fw6q 789 19 defined define VBN cord-006870-f5w6fw6q 789 20 as as IN cord-006870-f5w6fw6q 789 21 GOSE GOSE NNP cord-006870-f5w6fw6q 789 22 score score NN cord-006870-f5w6fw6q 789 23 5 5 CD cord-006870-f5w6fw6q 789 24 - - SYM cord-006870-f5w6fw6q 789 25 8 8 CD cord-006870-f5w6fw6q 789 26 and and CC cord-006870-f5w6fw6q 789 27 poor poor JJ cord-006870-f5w6fw6q 789 28 as as IN cord-006870-f5w6fw6q 789 29 GOSE GOSE NNP cord-006870-f5w6fw6q 789 30 score score NN cord-006870-f5w6fw6q 789 31 1 1 CD cord-006870-f5w6fw6q 789 32 - - SYM cord-006870-f5w6fw6q 789 33 4 4 CD cord-006870-f5w6fw6q 789 34 . . . cord-006870-f5w6fw6q 790 1 Volumetric volumetric JJ cord-006870-f5w6fw6q 790 2 measurements measurement NNS cord-006870-f5w6fw6q 790 3 of of IN cord-006870-f5w6fw6q 790 4 selected select VBN cord-006870-f5w6fw6q 790 5 brain brain NN cord-006870-f5w6fw6q 790 6 regions region NNS cord-006870-f5w6fw6q 790 7 , , , cord-006870-f5w6fw6q 790 8 both both CC cord-006870-f5w6fw6q 790 9 cortical cortical JJ cord-006870-f5w6fw6q 790 10 and and CC cord-006870-f5w6fw6q 790 11 subcortical subcortical JJ cord-006870-f5w6fw6q 790 12 , , , cord-006870-f5w6fw6q 790 13 were be VBD cord-006870-f5w6fw6q 790 14 obtained obtain VBN cord-006870-f5w6fw6q 790 15 at at IN cord-006870-f5w6fw6q 790 16 acute acute JJ cord-006870-f5w6fw6q 790 17 and and CC cord-006870-f5w6fw6q 790 18 chronic chronic JJ cord-006870-f5w6fw6q 790 19 time time NN cord-006870-f5w6fw6q 790 20 points point NNS cord-006870-f5w6fw6q 790 21 . . . cord-006870-f5w6fw6q 791 1 Quantitative quantitative JJ cord-006870-f5w6fw6q 791 2 parameters parameter NNS cord-006870-f5w6fw6q 791 3 derived derive VBN cord-006870-f5w6fw6q 791 4 from from IN cord-006870-f5w6fw6q 791 5 cEEG ceeg JJ cord-006870-f5w6fw6q 791 6 , , , cord-006870-f5w6fw6q 791 7 such such JJ cord-006870-f5w6fw6q 791 8 as as IN cord-006870-f5w6fw6q 791 9 percent percent NN cord-006870-f5w6fw6q 791 10 alpha alpha NN cord-006870-f5w6fw6q 791 11 variability variability NN cord-006870-f5w6fw6q 791 12 ( ( -LRB- cord-006870-f5w6fw6q 791 13 PAV PAV NNP cord-006870-f5w6fw6q 791 14 ) ) -RRB- cord-006870-f5w6fw6q 791 15 and and CC cord-006870-f5w6fw6q 791 16 hemispheric hemispheric JJ cord-006870-f5w6fw6q 791 17 symmetry symmetry NN cord-006870-f5w6fw6q 791 18 , , , cord-006870-f5w6fw6q 791 19 were be VBD cord-006870-f5w6fw6q 791 20 calculated calculate VBN cord-006870-f5w6fw6q 791 21 continuously continuously RB cord-006870-f5w6fw6q 791 22 and and CC cord-006870-f5w6fw6q 791 23 anatomically anatomically RB cord-006870-f5w6fw6q 791 24 ( ( -LRB- cord-006870-f5w6fw6q 791 25 frontal frontal JJ cord-006870-f5w6fw6q 791 26 , , , cord-006870-f5w6fw6q 791 27 temporal temporal JJ cord-006870-f5w6fw6q 791 28 , , , cord-006870-f5w6fw6q 791 29 occipital occipital NNP cord-006870-f5w6fw6q 791 30 ) ) -RRB- cord-006870-f5w6fw6q 791 31 through through IN cord-006870-f5w6fw6q 791 32 the the DT cord-006870-f5w6fw6q 791 33 acute acute JJ cord-006870-f5w6fw6q 791 34 hospitalization hospitalization NN cord-006870-f5w6fw6q 791 35 course course NN cord-006870-f5w6fw6q 791 36 . . . cord-006870-f5w6fw6q 792 1 We -PRON- PRP cord-006870-f5w6fw6q 792 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 792 3 that that IN cord-006870-f5w6fw6q 792 4 persistent persistent JJ cord-006870-f5w6fw6q 792 5 regional regional JJ cord-006870-f5w6fw6q 792 6 variation variation NN cord-006870-f5w6fw6q 792 7 in in IN cord-006870-f5w6fw6q 792 8 alpha alpha NN cord-006870-f5w6fw6q 792 9 power power NN cord-006870-f5w6fw6q 792 10 post post NN cord-006870-f5w6fw6q 792 11 injury injury NN cord-006870-f5w6fw6q 792 12 would would MD cord-006870-f5w6fw6q 792 13 lead lead VB cord-006870-f5w6fw6q 792 14 to to IN cord-006870-f5w6fw6q 792 15 brain brain NN cord-006870-f5w6fw6q 792 16 regionspecific regionspecific NN cord-006870-f5w6fw6q 792 17 atrophy atrophy NN cord-006870-f5w6fw6q 792 18 and and CC cord-006870-f5w6fw6q 792 19 may may MD cord-006870-f5w6fw6q 792 20 predict predict VB cord-006870-f5w6fw6q 792 21 outcome outcome NN cord-006870-f5w6fw6q 792 22 at at IN cord-006870-f5w6fw6q 792 23 6 6 CD cord-006870-f5w6fw6q 792 24 months month NNS cord-006870-f5w6fw6q 792 25 Acute acute JJ cord-006870-f5w6fw6q 792 26 PAV PAV NNP cord-006870-f5w6fw6q 792 27 within within IN cord-006870-f5w6fw6q 792 28 the the DT cord-006870-f5w6fw6q 792 29 first first JJ cord-006870-f5w6fw6q 792 30 48 48 CD cord-006870-f5w6fw6q 792 31 hours hour NNS cord-006870-f5w6fw6q 792 32 post post NN cord-006870-f5w6fw6q 792 33 injury injury NN cord-006870-f5w6fw6q 792 34 was be VBD cord-006870-f5w6fw6q 792 35 poor poor JJ cord-006870-f5w6fw6q 792 36 in in IN cord-006870-f5w6fw6q 792 37 patients patient NNS cord-006870-f5w6fw6q 792 38 with with IN cord-006870-f5w6fw6q 792 39 poor poor JJ cord-006870-f5w6fw6q 792 40 outcome outcome NN cord-006870-f5w6fw6q 792 41 . . . cord-006870-f5w6fw6q 793 1 In in IN cord-006870-f5w6fw6q 793 2 addition addition NN cord-006870-f5w6fw6q 793 3 , , , cord-006870-f5w6fw6q 793 4 patients patient NNS cord-006870-f5w6fw6q 793 5 with with IN cord-006870-f5w6fw6q 793 6 poor poor JJ cord-006870-f5w6fw6q 793 7 outcome outcome NN cord-006870-f5w6fw6q 793 8 had have VBD cord-006870-f5w6fw6q 793 9 significantly significantly RB cord-006870-f5w6fw6q 793 10 more more JJR cord-006870-f5w6fw6q 793 11 atrophy atrophy NN cord-006870-f5w6fw6q 793 12 in in IN cord-006870-f5w6fw6q 793 13 the the DT cord-006870-f5w6fw6q 793 14 thalamus thalamus NN cord-006870-f5w6fw6q 793 15 , , , cord-006870-f5w6fw6q 793 16 hippocampus hippocampus NN cord-006870-f5w6fw6q 793 17 , , , cord-006870-f5w6fw6q 793 18 and and CC cord-006870-f5w6fw6q 793 19 temporal temporal JJ cord-006870-f5w6fw6q 793 20 and and CC cord-006870-f5w6fw6q 793 21 occipital occipital JJ cord-006870-f5w6fw6q 793 22 lobes lobe NNS cord-006870-f5w6fw6q 793 23 . . . cord-006870-f5w6fw6q 794 1 Asymmetry asymmetry NN cord-006870-f5w6fw6q 794 2 of of IN cord-006870-f5w6fw6q 794 3 the the DT cord-006870-f5w6fw6q 794 4 hemisphere hemisphere NN cord-006870-f5w6fw6q 794 5 PAV PAV NNP cord-006870-f5w6fw6q 794 6 values value NNS cord-006870-f5w6fw6q 794 7 correlated correlate VBN cord-006870-f5w6fw6q 794 8 with with IN cord-006870-f5w6fw6q 794 9 both both DT cord-006870-f5w6fw6q 794 10 brain brain NN cord-006870-f5w6fw6q 794 11 atrophy atrophy NN cord-006870-f5w6fw6q 794 12 and and CC cord-006870-f5w6fw6q 794 13 clinical clinical JJ cord-006870-f5w6fw6q 794 14 outcome outcome NN cord-006870-f5w6fw6q 794 15 Regional regional JJ cord-006870-f5w6fw6q 794 16 asymmetry asymmetry NN cord-006870-f5w6fw6q 794 17 of of IN cord-006870-f5w6fw6q 794 18 PAV PAV NNP cord-006870-f5w6fw6q 794 19 within within IN cord-006870-f5w6fw6q 794 20 the the DT cord-006870-f5w6fw6q 794 21 first first JJ cord-006870-f5w6fw6q 794 22 48 48 CD cord-006870-f5w6fw6q 794 23 hours hour NNS cord-006870-f5w6fw6q 794 24 post post NN cord-006870-f5w6fw6q 794 25 injury injury NN cord-006870-f5w6fw6q 794 26 correlates correlate VBZ cord-006870-f5w6fw6q 794 27 with with IN cord-006870-f5w6fw6q 794 28 chronic chronic JJ cord-006870-f5w6fw6q 794 29 brain brain NN cord-006870-f5w6fw6q 794 30 atrophy atrophy NN cord-006870-f5w6fw6q 794 31 and and CC cord-006870-f5w6fw6q 794 32 clinical clinical JJ cord-006870-f5w6fw6q 794 33 outcome outcome NN cord-006870-f5w6fw6q 794 34 after after IN cord-006870-f5w6fw6q 794 35 TBI TBI NNP cord-006870-f5w6fw6q 794 36 After after IN cord-006870-f5w6fw6q 794 37 moderate moderate JJ cord-006870-f5w6fw6q 794 38 and and CC cord-006870-f5w6fw6q 794 39 severe severe JJ cord-006870-f5w6fw6q 794 40 traumatic traumatic JJ cord-006870-f5w6fw6q 794 41 brain brain NN cord-006870-f5w6fw6q 794 42 injuries injury NNS cord-006870-f5w6fw6q 794 43 ( ( -LRB- cord-006870-f5w6fw6q 794 44 TBIs TBIs NNP cord-006870-f5w6fw6q 794 45 ) ) -RRB- cord-006870-f5w6fw6q 794 46 , , , cord-006870-f5w6fw6q 794 47 individuals individual NNS cord-006870-f5w6fw6q 794 48 are be VBP cord-006870-f5w6fw6q 794 49 often often RB cord-006870-f5w6fw6q 794 50 admitted admit VBN cord-006870-f5w6fw6q 794 51 to to IN cord-006870-f5w6fw6q 794 52 an an DT cord-006870-f5w6fw6q 794 53 intensive intensive JJ cord-006870-f5w6fw6q 794 54 care care NN cord-006870-f5w6fw6q 794 55 unit unit NN cord-006870-f5w6fw6q 794 56 ( ( -LRB- cord-006870-f5w6fw6q 794 57 ICU ICU NNP cord-006870-f5w6fw6q 794 58 ) ) -RRB- cord-006870-f5w6fw6q 794 59 , , , cord-006870-f5w6fw6q 794 60 and and CC cord-006870-f5w6fw6q 794 61 later later RB cord-006870-f5w6fw6q 794 62 require require VB cord-006870-f5w6fw6q 794 63 intensive intensive JJ cord-006870-f5w6fw6q 794 64 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 794 65 . . . cord-006870-f5w6fw6q 795 1 Many many JJ cord-006870-f5w6fw6q 795 2 neuro neuro NNP cord-006870-f5w6fw6q 795 3 - - HYPH cord-006870-f5w6fw6q 795 4 ICUs ICUs NNP cord-006870-f5w6fw6q 795 5 engage engage VBP cord-006870-f5w6fw6q 795 6 therapists therapist NNS cord-006870-f5w6fw6q 795 7 and and CC cord-006870-f5w6fw6q 795 8 physiatrists physiatrist NNS cord-006870-f5w6fw6q 795 9 for for IN cord-006870-f5w6fw6q 795 10 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 795 11 and and CC cord-006870-f5w6fw6q 795 12 therapy therapy NN cord-006870-f5w6fw6q 795 13 during during IN cord-006870-f5w6fw6q 795 14 a a DT cord-006870-f5w6fw6q 795 15 patient patient NN cord-006870-f5w6fw6q 795 16 's 's POS cord-006870-f5w6fw6q 795 17 ICU ICU NNP cord-006870-f5w6fw6q 795 18 admission admission NN cord-006870-f5w6fw6q 795 19 . . . cord-006870-f5w6fw6q 796 1 However however RB cord-006870-f5w6fw6q 796 2 , , , cord-006870-f5w6fw6q 796 3 the the DT cord-006870-f5w6fw6q 796 4 optimal optimal JJ cord-006870-f5w6fw6q 796 5 timing timing NN cord-006870-f5w6fw6q 796 6 , , , cord-006870-f5w6fw6q 796 7 intensity intensity NN cord-006870-f5w6fw6q 796 8 , , , cord-006870-f5w6fw6q 796 9 and and CC cord-006870-f5w6fw6q 796 10 components component NNS cord-006870-f5w6fw6q 796 11 of of IN cord-006870-f5w6fw6q 796 12 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 796 13 needed need VBN cord-006870-f5w6fw6q 796 14 while while IN cord-006870-f5w6fw6q 796 15 in in IN cord-006870-f5w6fw6q 796 16 the the DT cord-006870-f5w6fw6q 796 17 ICU ICU NNP cord-006870-f5w6fw6q 796 18 are be VBP cord-006870-f5w6fw6q 796 19 not not RB cord-006870-f5w6fw6q 796 20 known know VBN cord-006870-f5w6fw6q 796 21 and and CC cord-006870-f5w6fw6q 796 22 practice practice NN cord-006870-f5w6fw6q 796 23 patterns pattern NNS cord-006870-f5w6fw6q 796 24 are be VBP cord-006870-f5w6fw6q 796 25 highly highly RB cord-006870-f5w6fw6q 796 26 variable variable JJ cord-006870-f5w6fw6q 796 27 . . . cord-006870-f5w6fw6q 797 1 The the DT cord-006870-f5w6fw6q 797 2 goal goal NN cord-006870-f5w6fw6q 797 3 of of IN cord-006870-f5w6fw6q 797 4 this this DT cord-006870-f5w6fw6q 797 5 study study NN cord-006870-f5w6fw6q 797 6 is be VBZ cord-006870-f5w6fw6q 797 7 to to TO cord-006870-f5w6fw6q 797 8 describe describe VB cord-006870-f5w6fw6q 797 9 the the DT cord-006870-f5w6fw6q 797 10 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 797 11 practices practice NNS cord-006870-f5w6fw6q 797 12 to to TO cord-006870-f5w6fw6q 797 13 identify identify VB cord-006870-f5w6fw6q 797 14 whether whether IN cord-006870-f5w6fw6q 797 15 there there EX cord-006870-f5w6fw6q 797 16 is be VBZ cord-006870-f5w6fw6q 797 17 consensus consensus NN cord-006870-f5w6fw6q 797 18 on on IN cord-006870-f5w6fw6q 797 19 best good JJS cord-006870-f5w6fw6q 797 20 practices practice NNS cord-006870-f5w6fw6q 797 21 . . . cord-006870-f5w6fw6q 798 1 An an DT cord-006870-f5w6fw6q 798 2 electronic electronic JJ cord-006870-f5w6fw6q 798 3 survey survey NN cord-006870-f5w6fw6q 798 4 asking ask VBG cord-006870-f5w6fw6q 798 5 participants participant NNS cord-006870-f5w6fw6q 798 6 to to TO cord-006870-f5w6fw6q 798 7 describe describe VB cord-006870-f5w6fw6q 798 8 TBI TBI NNP cord-006870-f5w6fw6q 798 9 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 798 10 practices practice NNS cord-006870-f5w6fw6q 798 11 in in IN cord-006870-f5w6fw6q 798 12 their -PRON- PRP$ cord-006870-f5w6fw6q 798 13 ICU ICU NNP cord-006870-f5w6fw6q 798 14 was be VBD cord-006870-f5w6fw6q 798 15 distributed distribute VBN cord-006870-f5w6fw6q 798 16 via via IN cord-006870-f5w6fw6q 798 17 REDCap REDCap NNS cord-006870-f5w6fw6q 798 18 through through IN cord-006870-f5w6fw6q 798 19 the the DT cord-006870-f5w6fw6q 798 20 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 798 21 Care Care NNP cord-006870-f5w6fw6q 798 22 Society Society NNP cord-006870-f5w6fw6q 798 23 ( ( -LRB- cord-006870-f5w6fw6q 798 24 NCS NCS NNP cord-006870-f5w6fw6q 798 25 ) ) -RRB- cord-006870-f5w6fw6q 798 26 and and CC cord-006870-f5w6fw6q 798 27 American American NNP cord-006870-f5w6fw6q 798 28 Congress Congress NNP cord-006870-f5w6fw6q 798 29 of of IN cord-006870-f5w6fw6q 798 30 Rehabilitation Rehabilitation NNP cord-006870-f5w6fw6q 798 31 Medicine Medicine NNP cord-006870-f5w6fw6q 798 32 ( ( -LRB- cord-006870-f5w6fw6q 798 33 ACRM ACRM NNP cord-006870-f5w6fw6q 798 34 ) ) -RRB- cord-006870-f5w6fw6q 798 35 websites website NNS cord-006870-f5w6fw6q 798 36 . . . cord-006870-f5w6fw6q 799 1 Potential potential JJ cord-006870-f5w6fw6q 799 2 respondents respondent NNS cord-006870-f5w6fw6q 799 3 were be VBD cord-006870-f5w6fw6q 799 4 first first RB cord-006870-f5w6fw6q 799 5 asked ask VBN cord-006870-f5w6fw6q 799 6 if if IN cord-006870-f5w6fw6q 799 7 they -PRON- PRP cord-006870-f5w6fw6q 799 8 cared care VBD cord-006870-f5w6fw6q 799 9 for for IN cord-006870-f5w6fw6q 799 10 patients patient NNS cord-006870-f5w6fw6q 799 11 with with IN cord-006870-f5w6fw6q 799 12 TBI TBI NNP cord-006870-f5w6fw6q 799 13 in in IN cord-006870-f5w6fw6q 799 14 the the DT cord-006870-f5w6fw6q 799 15 ICU ICU NNP cord-006870-f5w6fw6q 799 16 , , , cord-006870-f5w6fw6q 799 17 and and CC cord-006870-f5w6fw6q 799 18 if if IN cord-006870-f5w6fw6q 799 19 they -PRON- PRP cord-006870-f5w6fw6q 799 20 answered answer VBD cord-006870-f5w6fw6q 799 21 " " `` cord-006870-f5w6fw6q 799 22 yes yes UH cord-006870-f5w6fw6q 799 23 , , , cord-006870-f5w6fw6q 799 24 " " '' cord-006870-f5w6fw6q 799 25 they -PRON- PRP cord-006870-f5w6fw6q 799 26 were be VBD cord-006870-f5w6fw6q 799 27 invited invite VBN cord-006870-f5w6fw6q 799 28 to to TO cord-006870-f5w6fw6q 799 29 complete complete VB cord-006870-f5w6fw6q 799 30 the the DT cord-006870-f5w6fw6q 799 31 survey survey NN cord-006870-f5w6fw6q 799 32 . . . cord-006870-f5w6fw6q 800 1 Two two CD cord-006870-f5w6fw6q 800 2 email email NN cord-006870-f5w6fw6q 800 3 reminders reminder NNS cord-006870-f5w6fw6q 800 4 were be VBD cord-006870-f5w6fw6q 800 5 sent send VBN cord-006870-f5w6fw6q 800 6 to to IN cord-006870-f5w6fw6q 800 7 each each DT cord-006870-f5w6fw6q 800 8 group group NN cord-006870-f5w6fw6q 800 9 for for IN cord-006870-f5w6fw6q 800 10 completion completion NN cord-006870-f5w6fw6q 800 11 . . . cord-006870-f5w6fw6q 801 1 After after IN cord-006870-f5w6fw6q 801 2 51 51 CD cord-006870-f5w6fw6q 801 3 weeks week NNS cord-006870-f5w6fw6q 801 4 , , , cord-006870-f5w6fw6q 801 5 the the DT cord-006870-f5w6fw6q 801 6 data datum NNS cord-006870-f5w6fw6q 801 7 were be VBD cord-006870-f5w6fw6q 801 8 extracted extract VBN cord-006870-f5w6fw6q 801 9 and and CC cord-006870-f5w6fw6q 801 10 analysis analysis NN cord-006870-f5w6fw6q 801 11 completed complete VBN cord-006870-f5w6fw6q 801 12 . . . cord-006870-f5w6fw6q 802 1 There there EX cord-006870-f5w6fw6q 802 2 were be VBD cord-006870-f5w6fw6q 802 3 47 47 CD cord-006870-f5w6fw6q 802 4 respondents respondent NNS cord-006870-f5w6fw6q 802 5 who who WP cord-006870-f5w6fw6q 802 6 reported report VBD cord-006870-f5w6fw6q 802 7 that that IN cord-006870-f5w6fw6q 802 8 they -PRON- PRP cord-006870-f5w6fw6q 802 9 cared care VBD cord-006870-f5w6fw6q 802 10 for for IN cord-006870-f5w6fw6q 802 11 patients patient NNS cord-006870-f5w6fw6q 802 12 with with IN cord-006870-f5w6fw6q 802 13 TBI TBI NNP cord-006870-f5w6fw6q 802 14 in in IN cord-006870-f5w6fw6q 802 15 the the DT cord-006870-f5w6fw6q 802 16 ICU ICU NNP cord-006870-f5w6fw6q 802 17 ( ( -LRB- cord-006870-f5w6fw6q 802 18 17 17 CD cord-006870-f5w6fw6q 802 19 attending attend VBG cord-006870-f5w6fw6q 802 20 physicians physician NNS cord-006870-f5w6fw6q 802 21 , , , cord-006870-f5w6fw6q 802 22 6 6 CD cord-006870-f5w6fw6q 802 23 advanced advanced JJ cord-006870-f5w6fw6q 802 24 care care NN cord-006870-f5w6fw6q 802 25 practitioners practitioner NNS cord-006870-f5w6fw6q 802 26 , , , cord-006870-f5w6fw6q 802 27 15 15 CD cord-006870-f5w6fw6q 802 28 therapists therapist NNS cord-006870-f5w6fw6q 802 29 , , , cord-006870-f5w6fw6q 802 30 4 4 CD cord-006870-f5w6fw6q 802 31 nurses nurse NNS cord-006870-f5w6fw6q 802 32 , , , cord-006870-f5w6fw6q 802 33 4 4 CD cord-006870-f5w6fw6q 802 34 fellows fellow NNS cord-006870-f5w6fw6q 802 35 , , , cord-006870-f5w6fw6q 802 36 and and CC cord-006870-f5w6fw6q 802 37 1 1 CD cord-006870-f5w6fw6q 802 38 other other JJ cord-006870-f5w6fw6q 802 39 ) ) -RRB- cord-006870-f5w6fw6q 802 40 . . . cord-006870-f5w6fw6q 803 1 Of of IN cord-006870-f5w6fw6q 803 2 these these DT cord-006870-f5w6fw6q 803 3 , , , cord-006870-f5w6fw6q 803 4 96 96 CD cord-006870-f5w6fw6q 803 5 % % NN cord-006870-f5w6fw6q 803 6 recommended recommend VBD cord-006870-f5w6fw6q 803 7 early early JJ cord-006870-f5w6fw6q 803 8 rehabilitative rehabilitative JJ cord-006870-f5w6fw6q 803 9 care care NN cord-006870-f5w6fw6q 803 10 . . . cord-006870-f5w6fw6q 804 1 The the DT cord-006870-f5w6fw6q 804 2 most most RBS cord-006870-f5w6fw6q 804 3 common common JJ cord-006870-f5w6fw6q 804 4 reasons reason NNS cord-006870-f5w6fw6q 804 5 to to TO cord-006870-f5w6fw6q 804 6 wait wait VB cord-006870-f5w6fw6q 804 7 for for IN cord-006870-f5w6fw6q 804 8 the the DT cord-006870-f5w6fw6q 804 9 initiation initiation NN cord-006870-f5w6fw6q 804 10 of of IN cord-006870-f5w6fw6q 804 11 physical physical JJ cord-006870-f5w6fw6q 804 12 therapy therapy NN cord-006870-f5w6fw6q 804 13 and and CC cord-006870-f5w6fw6q 804 14 occupational occupational JJ cord-006870-f5w6fw6q 804 15 therapy therapy NN cord-006870-f5w6fw6q 804 16 were be VBD cord-006870-f5w6fw6q 804 17 normalization normalization NN cord-006870-f5w6fw6q 804 18 of of IN cord-006870-f5w6fw6q 804 19 intracranial intracranial JJ cord-006870-f5w6fw6q 804 20 pressure pressure NN cord-006870-f5w6fw6q 804 21 ( ( -LRB- cord-006870-f5w6fw6q 804 22 ICP ICP NNP cord-006870-f5w6fw6q 804 23 ) ) -RRB- cord-006870-f5w6fw6q 804 24 ( ( -LRB- cord-006870-f5w6fw6q 804 25 86 86 CD cord-006870-f5w6fw6q 804 26 % % NN cord-006870-f5w6fw6q 804 27 and and CC cord-006870-f5w6fw6q 804 28 89 89 CD cord-006870-f5w6fw6q 804 29 % % NN cord-006870-f5w6fw6q 804 30 respectively respectively RB cord-006870-f5w6fw6q 804 31 ) ) -RRB- cord-006870-f5w6fw6q 804 32 and and CC cord-006870-f5w6fw6q 804 33 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 804 34 stability stability NN cord-006870-f5w6fw6q 804 35 ( ( -LRB- cord-006870-f5w6fw6q 804 36 66 66 CD cord-006870-f5w6fw6q 804 37 % % NN cord-006870-f5w6fw6q 804 38 and and CC cord-006870-f5w6fw6q 804 39 69 69 CD cord-006870-f5w6fw6q 804 40 % % NN cord-006870-f5w6fw6q 804 41 respectively respectively RB cord-006870-f5w6fw6q 804 42 ) ) -RRB- cord-006870-f5w6fw6q 804 43 . . . cord-006870-f5w6fw6q 805 1 Speech speech NN cord-006870-f5w6fw6q 805 2 therapy therapy NN cord-006870-f5w6fw6q 805 3 was be VBD cord-006870-f5w6fw6q 805 4 typically typically RB cord-006870-f5w6fw6q 805 5 recommended recommend VBN cord-006870-f5w6fw6q 805 6 after after IN cord-006870-f5w6fw6q 805 7 extubation extubation NN cord-006870-f5w6fw6q 805 8 ( ( -LRB- cord-006870-f5w6fw6q 805 9 65 65 CD cord-006870-f5w6fw6q 805 10 % % NN cord-006870-f5w6fw6q 805 11 ) ) -RRB- cord-006870-f5w6fw6q 805 12 and and CC cord-006870-f5w6fw6q 805 13 normalization normalization NN cord-006870-f5w6fw6q 805 14 of of IN cord-006870-f5w6fw6q 805 15 ICP ICP NNP cord-006870-f5w6fw6q 805 16 ( ( -LRB- cord-006870-f5w6fw6q 805 17 58 58 CD cord-006870-f5w6fw6q 805 18 % % NN cord-006870-f5w6fw6q 805 19 ) ) -RRB- cord-006870-f5w6fw6q 805 20 . . . cord-006870-f5w6fw6q 806 1 The the DT cord-006870-f5w6fw6q 806 2 majority majority NN cord-006870-f5w6fw6q 806 3 of of IN cord-006870-f5w6fw6q 806 4 clinicians clinician NNS cord-006870-f5w6fw6q 806 5 caring care VBG cord-006870-f5w6fw6q 806 6 for for IN cord-006870-f5w6fw6q 806 7 patients patient NNS cord-006870-f5w6fw6q 806 8 with with IN cord-006870-f5w6fw6q 806 9 TBI TBI NNP cord-006870-f5w6fw6q 806 10 in in IN cord-006870-f5w6fw6q 806 11 the the DT cord-006870-f5w6fw6q 806 12 ICU ICU NNP cord-006870-f5w6fw6q 806 13 support support NN cord-006870-f5w6fw6q 806 14 early early JJ cord-006870-f5w6fw6q 806 15 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 806 16 efforts effort NNS cord-006870-f5w6fw6q 806 17 , , , cord-006870-f5w6fw6q 806 18 typically typically RB cord-006870-f5w6fw6q 806 19 after after IN cord-006870-f5w6fw6q 806 20 a a DT cord-006870-f5w6fw6q 806 21 patient patient NN cord-006870-f5w6fw6q 806 22 is be VBZ cord-006870-f5w6fw6q 806 23 extubated extubate VBN cord-006870-f5w6fw6q 806 24 , , , cord-006870-f5w6fw6q 806 25 intracranial intracranial JJ cord-006870-f5w6fw6q 806 26 pressure pressure NN cord-006870-f5w6fw6q 806 27 has have VBZ cord-006870-f5w6fw6q 806 28 normalized normalize VBN cord-006870-f5w6fw6q 806 29 and and CC cord-006870-f5w6fw6q 806 30 the the DT cord-006870-f5w6fw6q 806 31 patient patient NN cord-006870-f5w6fw6q 806 32 is be VBZ cord-006870-f5w6fw6q 806 33 hemodynamically hemodynamically RB cord-006870-f5w6fw6q 806 34 stable stable JJ cord-006870-f5w6fw6q 806 35 . . . cord-006870-f5w6fw6q 807 1 Prospective prospective JJ cord-006870-f5w6fw6q 807 2 studies study NNS cord-006870-f5w6fw6q 807 3 evaluating evaluate VBG cord-006870-f5w6fw6q 807 4 the the DT cord-006870-f5w6fw6q 807 5 merits merit NNS cord-006870-f5w6fw6q 807 6 of of IN cord-006870-f5w6fw6q 807 7 these these DT cord-006870-f5w6fw6q 807 8 self self NN cord-006870-f5w6fw6q 807 9 - - HYPH cord-006870-f5w6fw6q 807 10 reported report VBN cord-006870-f5w6fw6q 807 11 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 807 12 initiation initiation NN cord-006870-f5w6fw6q 807 13 criteria criterion NNS cord-006870-f5w6fw6q 807 14 are be VBP cord-006870-f5w6fw6q 807 15 warranted warrant VBN cord-006870-f5w6fw6q 807 16 . . . cord-006870-f5w6fw6q 808 1 High high JJ cord-006870-f5w6fw6q 808 2 - - HYPH cord-006870-f5w6fw6q 808 3 dose dose NN cord-006870-f5w6fw6q 808 4 methylprednisolone methylprednisolone NN cord-006870-f5w6fw6q 808 5 ( ( -LRB- cord-006870-f5w6fw6q 808 6 HDMP HDMP NNP cord-006870-f5w6fw6q 808 7 ) ) -RRB- cord-006870-f5w6fw6q 808 8 has have VBZ cord-006870-f5w6fw6q 808 9 been be VBN cord-006870-f5w6fw6q 808 10 studied study VBN cord-006870-f5w6fw6q 808 11 as as IN cord-006870-f5w6fw6q 808 12 a a DT cord-006870-f5w6fw6q 808 13 potential potential JJ cord-006870-f5w6fw6q 808 14 therapeutic therapeutic JJ cord-006870-f5w6fw6q 808 15 option option NN cord-006870-f5w6fw6q 808 16 for for IN cord-006870-f5w6fw6q 808 17 acute acute JJ cord-006870-f5w6fw6q 808 18 SCI SCI NNP cord-006870-f5w6fw6q 808 19 , , , cord-006870-f5w6fw6q 808 20 with with IN cord-006870-f5w6fw6q 808 21 mixed mixed JJ cord-006870-f5w6fw6q 808 22 results result NNS cord-006870-f5w6fw6q 808 23 regarding regard VBG cord-006870-f5w6fw6q 808 24 efficacy efficacy NN cord-006870-f5w6fw6q 808 25 and and CC cord-006870-f5w6fw6q 808 26 consistent consistent JJ cord-006870-f5w6fw6q 808 27 suggestion suggestion NN cord-006870-f5w6fw6q 808 28 of of IN cord-006870-f5w6fw6q 808 29 complications complication NNS cord-006870-f5w6fw6q 808 30 . . . cord-006870-f5w6fw6q 809 1 We -PRON- PRP cord-006870-f5w6fw6q 809 2 conducted conduct VBD cord-006870-f5w6fw6q 809 3 a a DT cord-006870-f5w6fw6q 809 4 retrospective retrospective JJ cord-006870-f5w6fw6q 809 5 cohort cohort NN cord-006870-f5w6fw6q 809 6 study study NN cord-006870-f5w6fw6q 809 7 of of IN cord-006870-f5w6fw6q 809 8 acute acute JJ cord-006870-f5w6fw6q 809 9 SCI SCI NNP cord-006870-f5w6fw6q 809 10 patients patient NNS cord-006870-f5w6fw6q 809 11 extracted extract VBN cord-006870-f5w6fw6q 809 12 from from IN cord-006870-f5w6fw6q 809 13 the the DT cord-006870-f5w6fw6q 809 14 Medical Medical NNP cord-006870-f5w6fw6q 809 15 Information Information NNP cord-006870-f5w6fw6q 809 16 Mart Mart NNP cord-006870-f5w6fw6q 809 17 for for IN cord-006870-f5w6fw6q 809 18 Intensive Intensive NNP cord-006870-f5w6fw6q 809 19 Care Care NNP cord-006870-f5w6fw6q 809 20 III III NNP cord-006870-f5w6fw6q 809 21 ( ( -LRB- cord-006870-f5w6fw6q 809 22 MIMIC MIMIC NNP cord-006870-f5w6fw6q 809 23 - - HYPH cord-006870-f5w6fw6q 809 24 III III NNP cord-006870-f5w6fw6q 809 25 ) ) -RRB- cord-006870-f5w6fw6q 809 26 database database NN cord-006870-f5w6fw6q 809 27 to to TO cord-006870-f5w6fw6q 809 28 evaluate evaluate VB cord-006870-f5w6fw6q 809 29 the the DT cord-006870-f5w6fw6q 809 30 hypothesis hypothesis NN cord-006870-f5w6fw6q 809 31 that that IN cord-006870-f5w6fw6q 809 32 steroid steroid NN cord-006870-f5w6fw6q 809 33 - - HYPH cord-006870-f5w6fw6q 809 34 related relate VBN cord-006870-f5w6fw6q 809 35 adverse adverse JJ cord-006870-f5w6fw6q 809 36 drug drug NN cord-006870-f5w6fw6q 809 37 events event NNS cord-006870-f5w6fw6q 809 38 ( ( -LRB- cord-006870-f5w6fw6q 809 39 ADEs ADEs NNP cord-006870-f5w6fw6q 809 40 ) ) -RRB- cord-006870-f5w6fw6q 809 41 occur occur VBP cord-006870-f5w6fw6q 809 42 less less RBR cord-006870-f5w6fw6q 809 43 often often RB cord-006870-f5w6fw6q 809 44 than than IN cord-006870-f5w6fw6q 809 45 in in IN cord-006870-f5w6fw6q 809 46 published publish VBN cord-006870-f5w6fw6q 809 47 clinical clinical JJ cord-006870-f5w6fw6q 809 48 trials trial NNS cord-006870-f5w6fw6q 809 49 using use VBG cord-006870-f5w6fw6q 809 50 HDMP HDMP NNP cord-006870-f5w6fw6q 809 51 . . . cord-006870-f5w6fw6q 810 1 Three three CD cord-006870-f5w6fw6q 810 2 groups group NNS cord-006870-f5w6fw6q 810 3 of of IN cord-006870-f5w6fw6q 810 4 patients patient NNS cord-006870-f5w6fw6q 810 5 coded code VBN cord-006870-f5w6fw6q 810 6 for for IN cord-006870-f5w6fw6q 810 7 acute acute JJ cord-006870-f5w6fw6q 810 8 SCI SCI NNP cord-006870-f5w6fw6q 810 9 were be VBD cord-006870-f5w6fw6q 810 10 identified identify VBN cord-006870-f5w6fw6q 810 11 from from IN cord-006870-f5w6fw6q 810 12 MIMIC MIMIC NNP cord-006870-f5w6fw6q 810 13 - - HYPH cord-006870-f5w6fw6q 810 14 III III NNP cord-006870-f5w6fw6q 810 15 from from IN cord-006870-f5w6fw6q 810 16 June June NNP cord-006870-f5w6fw6q 810 17 2001 2001 CD cord-006870-f5w6fw6q 810 18 to to IN cord-006870-f5w6fw6q 810 19 October October NNP cord-006870-f5w6fw6q 810 20 2012 2012 CD cord-006870-f5w6fw6q 810 21 : : : cord-006870-f5w6fw6q 811 1 HDMP HDMP NNP cord-006870-f5w6fw6q 811 2 recipients recipient NNS cord-006870-f5w6fw6q 811 3 per per IN cord-006870-f5w6fw6q 811 4 NASCIS NASCIS NNP cord-006870-f5w6fw6q 811 5 II II NNP cord-006870-f5w6fw6q 811 6 / / SYM cord-006870-f5w6fw6q 811 7 III iii CD cord-006870-f5w6fw6q 811 8 protocols protocol NNS cord-006870-f5w6fw6q 811 9 ( ( -LRB- cord-006870-f5w6fw6q 811 10 HDMP HDMP NNP cord-006870-f5w6fw6q 811 11 , , , cord-006870-f5w6fw6q 811 12 n n NN cord-006870-f5w6fw6q 811 13 = = SYM cord-006870-f5w6fw6q 811 14 55 55 CD cord-006870-f5w6fw6q 811 15 ) ) -RRB- cord-006870-f5w6fw6q 811 16 , , , cord-006870-f5w6fw6q 811 17 patients patient NNS cord-006870-f5w6fw6q 811 18 who who WP cord-006870-f5w6fw6q 811 19 received receive VBD cord-006870-f5w6fw6q 811 20 some some DT cord-006870-f5w6fw6q 811 21 steroids steroid NNS cord-006870-f5w6fw6q 811 22 but but CC cord-006870-f5w6fw6q 811 23 not not RB cord-006870-f5w6fw6q 811 24 per per IN cord-006870-f5w6fw6q 811 25 NASCIS NASCIS NNP cord-006870-f5w6fw6q 811 26 II II NNP cord-006870-f5w6fw6q 811 27 / / SYM cord-006870-f5w6fw6q 811 28 III iii CD cord-006870-f5w6fw6q 811 29 protocols protocol NNS cord-006870-f5w6fw6q 811 30 ( ( -LRB- cord-006870-f5w6fw6q 811 31 Non Non NNP cord-006870-f5w6fw6q 811 32 - - NNP cord-006870-f5w6fw6q 811 33 HDMP HDMP NNP cord-006870-f5w6fw6q 811 34 , , , cord-006870-f5w6fw6q 811 35 n n NN cord-006870-f5w6fw6q 811 36 = = SYM cord-006870-f5w6fw6q 811 37 47 47 CD cord-006870-f5w6fw6q 811 38 ) ) -RRB- cord-006870-f5w6fw6q 811 39 , , , cord-006870-f5w6fw6q 811 40 and and CC cord-006870-f5w6fw6q 811 41 patients patient NNS cord-006870-f5w6fw6q 811 42 who who WP cord-006870-f5w6fw6q 811 43 did do VBD cord-006870-f5w6fw6q 811 44 not not RB cord-006870-f5w6fw6q 811 45 receive receive VB cord-006870-f5w6fw6q 811 46 steroids steroid NNS cord-006870-f5w6fw6q 811 47 ( ( -LRB- cord-006870-f5w6fw6q 811 48 No no DT cord-006870-f5w6fw6q 811 49 Steroids Steroids NNP cord-006870-f5w6fw6q 811 50 , , , cord-006870-f5w6fw6q 811 51 n n NN cord-006870-f5w6fw6q 811 52 = = SYM cord-006870-f5w6fw6q 811 53 198 198 CD cord-006870-f5w6fw6q 811 54 ) ) -RRB- cord-006870-f5w6fw6q 811 55 . . . cord-006870-f5w6fw6q 812 1 Demographics demographic NNS cord-006870-f5w6fw6q 812 2 and and CC cord-006870-f5w6fw6q 812 3 data datum NNS cord-006870-f5w6fw6q 812 4 on on IN cord-006870-f5w6fw6q 812 5 complications complication NNS cord-006870-f5w6fw6q 812 6 of of IN cord-006870-f5w6fw6q 812 7 steroid steroid NN cord-006870-f5w6fw6q 812 8 therapy therapy NN cord-006870-f5w6fw6q 812 9 were be VBD cord-006870-f5w6fw6q 812 10 extracted extract VBN cord-006870-f5w6fw6q 812 11 . . . cord-006870-f5w6fw6q 813 1 One one CD cord-006870-f5w6fw6q 813 2 - - HYPH cord-006870-f5w6fw6q 813 3 way way NN cord-006870-f5w6fw6q 813 4 ANOVA ANOVA NNP cord-006870-f5w6fw6q 813 5 or or CC cord-006870-f5w6fw6q 813 6 Student Student NNP cord-006870-f5w6fw6q 813 7 's 's POS cord-006870-f5w6fw6q 813 8 t t NN cord-006870-f5w6fw6q 813 9 test test NN cord-006870-f5w6fw6q 813 10 were be VBD cord-006870-f5w6fw6q 813 11 used use VBN cord-006870-f5w6fw6q 813 12 to to TO cord-006870-f5w6fw6q 813 13 evaluate evaluate VB cord-006870-f5w6fw6q 813 14 continuous continuous JJ cord-006870-f5w6fw6q 813 15 variables variable NNS cord-006870-f5w6fw6q 813 16 ; ; : cord-006870-f5w6fw6q 813 17 chi chi JJ cord-006870-f5w6fw6q 813 18 - - HYPH cord-006870-f5w6fw6q 813 19 squared squared JJ cord-006870-f5w6fw6q 813 20 or or CC cord-006870-f5w6fw6q 813 21 Fisher Fisher NNP cord-006870-f5w6fw6q 813 22 's 's POS cord-006870-f5w6fw6q 813 23 exact exact JJ cord-006870-f5w6fw6q 813 24 test test NN cord-006870-f5w6fw6q 813 25 were be VBD cord-006870-f5w6fw6q 813 26 used use VBN cord-006870-f5w6fw6q 813 27 for for IN cord-006870-f5w6fw6q 813 28 nominal nominal JJ cord-006870-f5w6fw6q 813 29 or or CC cord-006870-f5w6fw6q 813 30 categorical categorical JJ cord-006870-f5w6fw6q 813 31 variables variable NNS cord-006870-f5w6fw6q 813 32 . . . cord-006870-f5w6fw6q 814 1 There there EX cord-006870-f5w6fw6q 814 2 were be VBD cord-006870-f5w6fw6q 814 3 no no DT cord-006870-f5w6fw6q 814 4 differences difference NNS cord-006870-f5w6fw6q 814 5 in in IN cord-006870-f5w6fw6q 814 6 steroid steroid NN cord-006870-f5w6fw6q 814 7 - - HYPH cord-006870-f5w6fw6q 814 8 related relate VBN cord-006870-f5w6fw6q 814 9 ADEs ade NNS cord-006870-f5w6fw6q 814 10 between between IN cord-006870-f5w6fw6q 814 11 the the DT cord-006870-f5w6fw6q 814 12 three three CD cord-006870-f5w6fw6q 814 13 groups group NNS cord-006870-f5w6fw6q 814 14 . . . cord-006870-f5w6fw6q 815 1 There there EX cord-006870-f5w6fw6q 815 2 were be VBD cord-006870-f5w6fw6q 815 3 higher high JJR cord-006870-f5w6fw6q 815 4 average average JJ cord-006870-f5w6fw6q 815 5 blood blood NN cord-006870-f5w6fw6q 815 6 glucose glucose NN cord-006870-f5w6fw6q 815 7 readings reading NNS cord-006870-f5w6fw6q 815 8 in in IN cord-006870-f5w6fw6q 815 9 recipients recipient NNS cord-006870-f5w6fw6q 815 10 of of IN cord-006870-f5w6fw6q 815 11 any any DT cord-006870-f5w6fw6q 815 12 steroids steroid NNS cord-006870-f5w6fw6q 815 13 compared compare VBN cord-006870-f5w6fw6q 815 14 with with IN cord-006870-f5w6fw6q 815 15 the the DT cord-006870-f5w6fw6q 815 16 No No NNP cord-006870-f5w6fw6q 815 17 Steroids Steroids NNP cord-006870-f5w6fw6q 815 18 group group NN cord-006870-f5w6fw6q 815 19 , , , cord-006870-f5w6fw6q 815 20 and and CC cord-006870-f5w6fw6q 815 21 more more JJR cord-006870-f5w6fw6q 815 22 variation variation NN cord-006870-f5w6fw6q 815 23 in in IN cord-006870-f5w6fw6q 815 24 blood blood NN cord-006870-f5w6fw6q 815 25 glucose glucose NN cord-006870-f5w6fw6q 815 26 readings reading NNS cord-006870-f5w6fw6q 815 27 in in IN cord-006870-f5w6fw6q 815 28 HDMP HDMP NNP cord-006870-f5w6fw6q 815 29 recipients recipient NNS cord-006870-f5w6fw6q 815 30 compared compare VBN cord-006870-f5w6fw6q 815 31 with with IN cord-006870-f5w6fw6q 815 32 the the DT cord-006870-f5w6fw6q 815 33 other other JJ cord-006870-f5w6fw6q 815 34 two two CD cord-006870-f5w6fw6q 815 35 groups group NNS cord-006870-f5w6fw6q 815 36 . . . cord-006870-f5w6fw6q 816 1 There there EX cord-006870-f5w6fw6q 816 2 was be VBD cord-006870-f5w6fw6q 816 3 a a DT cord-006870-f5w6fw6q 816 4 higher high JJR cord-006870-f5w6fw6q 816 5 ICU ICU NNP cord-006870-f5w6fw6q 816 6 LOS LOS NNP cord-006870-f5w6fw6q 816 7 and and CC cord-006870-f5w6fw6q 816 8 ventilator ventilator NN cord-006870-f5w6fw6q 816 9 time time NN cord-006870-f5w6fw6q 816 10 in in IN cord-006870-f5w6fw6q 816 11 the the DT cord-006870-f5w6fw6q 816 12 HDMP HDMP NNP cord-006870-f5w6fw6q 816 13 group group NN cord-006870-f5w6fw6q 816 14 compared compare VBN cord-006870-f5w6fw6q 816 15 with with IN cord-006870-f5w6fw6q 816 16 the the DT cord-006870-f5w6fw6q 816 17 other other JJ cord-006870-f5w6fw6q 816 18 two two CD cord-006870-f5w6fw6q 816 19 groups group NNS cord-006870-f5w6fw6q 816 20 . . . cord-006870-f5w6fw6q 817 1 Compared compare VBN cord-006870-f5w6fw6q 817 2 with with IN cord-006870-f5w6fw6q 817 3 three three CD cord-006870-f5w6fw6q 817 4 other other JJ cord-006870-f5w6fw6q 817 5 trials trial NNS cord-006870-f5w6fw6q 817 6 examining examine VBG cord-006870-f5w6fw6q 817 7 similar similar JJ cord-006870-f5w6fw6q 817 8 use use NN cord-006870-f5w6fw6q 817 9 of of IN cord-006870-f5w6fw6q 817 10 HDMP HDMP NNP cord-006870-f5w6fw6q 817 11 in in IN cord-006870-f5w6fw6q 817 12 acute acute JJ cord-006870-f5w6fw6q 817 13 SCI SCI NNP cord-006870-f5w6fw6q 817 14 , , , cord-006870-f5w6fw6q 817 15 there there EX cord-006870-f5w6fw6q 817 16 were be VBD cord-006870-f5w6fw6q 817 17 higher high JJR cord-006870-f5w6fw6q 817 18 rates rate NNS cord-006870-f5w6fw6q 817 19 of of IN cord-006870-f5w6fw6q 817 20 pneumonias pneumonia NNS cord-006870-f5w6fw6q 817 21 overall overall RB cord-006870-f5w6fw6q 817 22 , , , cord-006870-f5w6fw6q 817 23 though though IN cord-006870-f5w6fw6q 817 24 lower low JJR cord-006870-f5w6fw6q 817 25 rates rate NNS cord-006870-f5w6fw6q 817 26 of of IN cord-006870-f5w6fw6q 817 27 urinary urinary JJ cord-006870-f5w6fw6q 817 28 tract tract JJ cord-006870-f5w6fw6q 817 29 infections infection NNS cord-006870-f5w6fw6q 817 30 , , , cord-006870-f5w6fw6q 817 31 skin skin NN cord-006870-f5w6fw6q 817 32 & & CC cord-006870-f5w6fw6q 817 33 soft soft JJ cord-006870-f5w6fw6q 817 34 tissue tissue NN cord-006870-f5w6fw6q 817 35 infections infection NNS cord-006870-f5w6fw6q 817 36 , , , cord-006870-f5w6fw6q 817 37 pressure pressure NN cord-006870-f5w6fw6q 817 38 ulcers ulcer NNS cord-006870-f5w6fw6q 817 39 , , , cord-006870-f5w6fw6q 817 40 and and CC cord-006870-f5w6fw6q 817 41 superficial superficial JJ cord-006870-f5w6fw6q 817 42 thromboemboli thromboemboli NNS cord-006870-f5w6fw6q 817 43 / / SYM cord-006870-f5w6fw6q 817 44 thrombophlebitis thrombophlebitis NNP cord-006870-f5w6fw6q 817 45 . . . cord-006870-f5w6fw6q 818 1 The the DT cord-006870-f5w6fw6q 818 2 results result NNS cord-006870-f5w6fw6q 818 3 of of IN cord-006870-f5w6fw6q 818 4 this this DT cord-006870-f5w6fw6q 818 5 study study NN cord-006870-f5w6fw6q 818 6 are be VBP cord-006870-f5w6fw6q 818 7 consistent consistent JJ cord-006870-f5w6fw6q 818 8 with with IN cord-006870-f5w6fw6q 818 9 previous previous JJ cord-006870-f5w6fw6q 818 10 works work NNS cord-006870-f5w6fw6q 818 11 related relate VBN cord-006870-f5w6fw6q 818 12 to to IN cord-006870-f5w6fw6q 818 13 the the DT cord-006870-f5w6fw6q 818 14 potential potential NN cord-006870-f5w6fw6q 818 15 for for IN cord-006870-f5w6fw6q 818 16 harm harm NN cord-006870-f5w6fw6q 818 17 regarding regard VBG cord-006870-f5w6fw6q 818 18 the the DT cord-006870-f5w6fw6q 818 19 use use NN cord-006870-f5w6fw6q 818 20 of of IN cord-006870-f5w6fw6q 818 21 HDMP HDMP NNP cord-006870-f5w6fw6q 818 22 or or CC cord-006870-f5w6fw6q 818 23 any any DT cord-006870-f5w6fw6q 818 24 steroids steroid NNS cord-006870-f5w6fw6q 818 25 in in IN cord-006870-f5w6fw6q 818 26 acute acute JJ cord-006870-f5w6fw6q 818 27 SCI SCI NNP cord-006870-f5w6fw6q 818 28 . . . cord-006870-f5w6fw6q 819 1 Changes change NNS cord-006870-f5w6fw6q 819 2 in in IN cord-006870-f5w6fw6q 819 3 selected select VBN cord-006870-f5w6fw6q 819 4 adverse adverse JJ cord-006870-f5w6fw6q 819 5 event event NN cord-006870-f5w6fw6q 819 6 profiles profile NNS cord-006870-f5w6fw6q 819 7 may may MD cord-006870-f5w6fw6q 819 8 be be VB cord-006870-f5w6fw6q 819 9 due due JJ cord-006870-f5w6fw6q 819 10 to to IN cord-006870-f5w6fw6q 819 11 standardization standardization NN cord-006870-f5w6fw6q 819 12 of of IN cord-006870-f5w6fw6q 819 13 ICU ICU NNP cord-006870-f5w6fw6q 819 14 supportive supportive JJ cord-006870-f5w6fw6q 819 15 care care NN cord-006870-f5w6fw6q 819 16 over over IN cord-006870-f5w6fw6q 819 17 time time NN cord-006870-f5w6fw6q 819 18 . . . cord-006870-f5w6fw6q 820 1 Cervical cervical JJ cord-006870-f5w6fw6q 820 2 spinal spinal JJ cord-006870-f5w6fw6q 820 3 immobilization immobilization NN cord-006870-f5w6fw6q 820 4 and and CC cord-006870-f5w6fw6q 820 5 clearance clearance NN cord-006870-f5w6fw6q 820 6 protocols protocol NNS cord-006870-f5w6fw6q 820 7 are be VBP cord-006870-f5w6fw6q 820 8 important important JJ cord-006870-f5w6fw6q 820 9 steps step NNS cord-006870-f5w6fw6q 820 10 in in IN cord-006870-f5w6fw6q 820 11 the the DT cord-006870-f5w6fw6q 820 12 minimization minimization NN cord-006870-f5w6fw6q 820 13 of of IN cord-006870-f5w6fw6q 820 14 secondary secondary JJ cord-006870-f5w6fw6q 820 15 spinal spinal JJ cord-006870-f5w6fw6q 820 16 cord cord NN cord-006870-f5w6fw6q 820 17 injury injury NN cord-006870-f5w6fw6q 820 18 . . . cord-006870-f5w6fw6q 821 1 Patients patient NNS cord-006870-f5w6fw6q 821 2 with with IN cord-006870-f5w6fw6q 821 3 primary primary JJ cord-006870-f5w6fw6q 821 4 neurologic neurologic JJ cord-006870-f5w6fw6q 821 5 diseases disease NNS cord-006870-f5w6fw6q 821 6 are be VBP cord-006870-f5w6fw6q 821 7 frequently frequently RB cord-006870-f5w6fw6q 821 8 found find VBN cord-006870-f5w6fw6q 821 9 down down RP cord-006870-f5w6fw6q 821 10 and and CC cord-006870-f5w6fw6q 821 11 placed place VBN cord-006870-f5w6fw6q 821 12 in in IN cord-006870-f5w6fw6q 821 13 rigid rigid JJ cord-006870-f5w6fw6q 821 14 cervical cervical JJ cord-006870-f5w6fw6q 821 15 collars collar NNS cord-006870-f5w6fw6q 821 16 despite despite IN cord-006870-f5w6fw6q 821 17 sustaining sustain VBG cord-006870-f5w6fw6q 821 18 minimal minimal JJ cord-006870-f5w6fw6q 821 19 - - HYPH cord-006870-f5w6fw6q 821 20 to to IN cord-006870-f5w6fw6q 821 21 - - HYPH cord-006870-f5w6fw6q 821 22 no no DT cord-006870-f5w6fw6q 821 23 cervical cervical JJ cord-006870-f5w6fw6q 821 24 injury injury NN cord-006870-f5w6fw6q 821 25 . . . cord-006870-f5w6fw6q 822 1 In in IN cord-006870-f5w6fw6q 822 2 these these DT cord-006870-f5w6fw6q 822 3 patients patient NNS cord-006870-f5w6fw6q 822 4 , , , cord-006870-f5w6fw6q 822 5 neurologic neurologic JJ cord-006870-f5w6fw6q 822 6 dysfunction dysfunction NN cord-006870-f5w6fw6q 822 7 can can MD cord-006870-f5w6fw6q 822 8 complicate complicate VB cord-006870-f5w6fw6q 822 9 and and CC cord-006870-f5w6fw6q 822 10 delay delay VB cord-006870-f5w6fw6q 822 11 cervical cervical JJ cord-006870-f5w6fw6q 822 12 clearance clearance NN cord-006870-f5w6fw6q 822 13 . . . cord-006870-f5w6fw6q 823 1 Decreasing decrease VBG cord-006870-f5w6fw6q 823 2 time time NN cord-006870-f5w6fw6q 823 3 spent spend VBN cord-006870-f5w6fw6q 823 4 in in IN cord-006870-f5w6fw6q 823 5 cervical cervical JJ cord-006870-f5w6fw6q 823 6 spinal spinal JJ cord-006870-f5w6fw6q 823 7 immobilization immobilization NN cord-006870-f5w6fw6q 823 8 could could MD cord-006870-f5w6fw6q 823 9 improve improve VB cord-006870-f5w6fw6q 823 10 patient patient JJ cord-006870-f5w6fw6q 823 11 care care NN cord-006870-f5w6fw6q 823 12 by by IN cord-006870-f5w6fw6q 823 13 allowing allow VBG cord-006870-f5w6fw6q 823 14 greater great JJR cord-006870-f5w6fw6q 823 15 access access NN cord-006870-f5w6fw6q 823 16 to to IN cord-006870-f5w6fw6q 823 17 / / SYM cord-006870-f5w6fw6q 823 18 range range NN cord-006870-f5w6fw6q 823 19 - - HYPH cord-006870-f5w6fw6q 823 20 of of IN cord-006870-f5w6fw6q 823 21 - - HYPH cord-006870-f5w6fw6q 823 22 motion motion NN cord-006870-f5w6fw6q 823 23 of of IN cord-006870-f5w6fw6q 823 24 the the DT cord-006870-f5w6fw6q 823 25 neck neck NN cord-006870-f5w6fw6q 823 26 , , , cord-006870-f5w6fw6q 823 27 increasing increase VBG cord-006870-f5w6fw6q 823 28 patient patient JJ cord-006870-f5w6fw6q 823 29 comfort comfort NN cord-006870-f5w6fw6q 823 30 , , , cord-006870-f5w6fw6q 823 31 and and CC cord-006870-f5w6fw6q 823 32 decreasing decrease VBG cord-006870-f5w6fw6q 823 33 skin skin NN cord-006870-f5w6fw6q 823 34 breakdown breakdown NN cord-006870-f5w6fw6q 823 35 . . . cord-006870-f5w6fw6q 824 1 Through through IN cord-006870-f5w6fw6q 824 2 retrospective retrospective JJ cord-006870-f5w6fw6q 824 3 chart chart NN cord-006870-f5w6fw6q 824 4 review review NN cord-006870-f5w6fw6q 824 5 over over IN cord-006870-f5w6fw6q 824 6 a a DT cord-006870-f5w6fw6q 824 7 28-month 28-month JJ cord-006870-f5w6fw6q 824 8 period period NN cord-006870-f5w6fw6q 824 9 , , , cord-006870-f5w6fw6q 824 10 we -PRON- PRP cord-006870-f5w6fw6q 824 11 collected collect VBD cord-006870-f5w6fw6q 824 12 the the DT cord-006870-f5w6fw6q 824 13 following follow VBG cord-006870-f5w6fw6q 824 14 : : : cord-006870-f5w6fw6q 824 15 the the DT cord-006870-f5w6fw6q 824 16 rationale rationale NN cord-006870-f5w6fw6q 824 17 behind behind IN cord-006870-f5w6fw6q 824 18 each each DT cord-006870-f5w6fw6q 824 19 MRI MRI NNP cord-006870-f5w6fw6q 824 20 , , , cord-006870-f5w6fw6q 824 21 any any DT cord-006870-f5w6fw6q 824 22 MRI MRI NNP cord-006870-f5w6fw6q 824 23 evidence evidence NN cord-006870-f5w6fw6q 824 24 of of IN cord-006870-f5w6fw6q 824 25 cervical cervical JJ cord-006870-f5w6fw6q 824 26 instability instability NN cord-006870-f5w6fw6q 824 27 , , , cord-006870-f5w6fw6q 824 28 the the DT cord-006870-f5w6fw6q 824 29 result result NN cord-006870-f5w6fw6q 824 30 of of IN cord-006870-f5w6fw6q 824 31 any any DT cord-006870-f5w6fw6q 824 32 CT CT NNP cord-006870-f5w6fw6q 824 33 imaging imaging NN cord-006870-f5w6fw6q 824 34 , , , cord-006870-f5w6fw6q 824 35 and and CC cord-006870-f5w6fw6q 824 36 the the DT cord-006870-f5w6fw6q 824 37 basic basic JJ cord-006870-f5w6fw6q 824 38 mechanism mechanism NN cord-006870-f5w6fw6q 824 39 of of IN cord-006870-f5w6fw6q 824 40 any any DT cord-006870-f5w6fw6q 824 41 trauma trauma NN cord-006870-f5w6fw6q 824 42 . . . cord-006870-f5w6fw6q 825 1 For for IN cord-006870-f5w6fw6q 825 2 patients patient NNS cord-006870-f5w6fw6q 825 3 that that WDT cord-006870-f5w6fw6q 825 4 were be VBD cord-006870-f5w6fw6q 825 5 simply simply RB cord-006870-f5w6fw6q 825 6 found find VBN cord-006870-f5w6fw6q 825 7 down down RP cord-006870-f5w6fw6q 825 8 , , , cord-006870-f5w6fw6q 825 9 any any DT cord-006870-f5w6fw6q 825 10 evidence evidence NN cord-006870-f5w6fw6q 825 11 of of IN cord-006870-f5w6fw6q 825 12 trauma trauma NN cord-006870-f5w6fw6q 825 13 either either CC cord-006870-f5w6fw6q 825 14 by by IN cord-006870-f5w6fw6q 825 15 history history NN cord-006870-f5w6fw6q 825 16 or or CC cord-006870-f5w6fw6q 825 17 physical physical JJ cord-006870-f5w6fw6q 825 18 exam exam NN cord-006870-f5w6fw6q 825 19 was be VBD cord-006870-f5w6fw6q 825 20 recorded record VBN cord-006870-f5w6fw6q 825 21 . . . cord-006870-f5w6fw6q 826 1 During during IN cord-006870-f5w6fw6q 826 2 the the DT cord-006870-f5w6fw6q 826 3 study study NN cord-006870-f5w6fw6q 826 4 period period NN cord-006870-f5w6fw6q 826 5 , , , cord-006870-f5w6fw6q 826 6 there there EX cord-006870-f5w6fw6q 826 7 were be VBD cord-006870-f5w6fw6q 826 8 306 306 CD cord-006870-f5w6fw6q 826 9 instances instance NNS cord-006870-f5w6fw6q 826 10 where where WRB cord-006870-f5w6fw6q 826 11 an an DT cord-006870-f5w6fw6q 826 12 MRI MRI NNP cord-006870-f5w6fw6q 826 13 of of IN cord-006870-f5w6fw6q 826 14 the the DT cord-006870-f5w6fw6q 826 15 cervical cervical JJ cord-006870-f5w6fw6q 826 16 spine spine NN cord-006870-f5w6fw6q 826 17 was be VBD cord-006870-f5w6fw6q 826 18 performed perform VBN cord-006870-f5w6fw6q 826 19 . . . cord-006870-f5w6fw6q 827 1 Of of IN cord-006870-f5w6fw6q 827 2 those those DT cord-006870-f5w6fw6q 827 3 MRIs mri NNS cord-006870-f5w6fw6q 827 4 , , , cord-006870-f5w6fw6q 827 5 176 176 CD cord-006870-f5w6fw6q 827 6 ( ( -LRB- cord-006870-f5w6fw6q 827 7 58 58 CD cord-006870-f5w6fw6q 827 8 % % NN cord-006870-f5w6fw6q 827 9 ) ) -RRB- cord-006870-f5w6fw6q 827 10 , , , cord-006870-f5w6fw6q 827 11 were be VBD cord-006870-f5w6fw6q 827 12 performed perform VBN cord-006870-f5w6fw6q 827 13 for for IN cord-006870-f5w6fw6q 827 14 cervical cervical JJ cord-006870-f5w6fw6q 827 15 spinal spinal JJ cord-006870-f5w6fw6q 827 16 clearance clearance NN cord-006870-f5w6fw6q 827 17 . . . cord-006870-f5w6fw6q 828 1 Sixty sixty CD cord-006870-f5w6fw6q 828 2 - - HYPH cord-006870-f5w6fw6q 828 3 one one CD cord-006870-f5w6fw6q 828 4 ( ( -LRB- cord-006870-f5w6fw6q 828 5 35 35 CD cord-006870-f5w6fw6q 828 6 % % NN cord-006870-f5w6fw6q 828 7 ) ) -RRB- cord-006870-f5w6fw6q 828 8 of of IN cord-006870-f5w6fw6q 828 9 MRIs mri NNS cord-006870-f5w6fw6q 828 10 were be VBD cord-006870-f5w6fw6q 828 11 ordered order VBN cord-006870-f5w6fw6q 828 12 without without IN cord-006870-f5w6fw6q 828 13 any any DT cord-006870-f5w6fw6q 828 14 CT CT NNP cord-006870-f5w6fw6q 828 15 imaging imaging NN cord-006870-f5w6fw6q 828 16 first first RB cord-006870-f5w6fw6q 828 17 . . . cord-006870-f5w6fw6q 829 1 Of of IN cord-006870-f5w6fw6q 829 2 the the DT cord-006870-f5w6fw6q 829 3 patients patient NNS cord-006870-f5w6fw6q 829 4 with with IN cord-006870-f5w6fw6q 829 5 a a DT cord-006870-f5w6fw6q 829 6 normal normal JJ cord-006870-f5w6fw6q 829 7 CT CT NNP cord-006870-f5w6fw6q 829 8 , , , cord-006870-f5w6fw6q 829 9 six six CD cord-006870-f5w6fw6q 829 10 ( ( -LRB- cord-006870-f5w6fw6q 829 11 3.4 3.4 CD cord-006870-f5w6fw6q 829 12 % % NN cord-006870-f5w6fw6q 829 13 ) ) -RRB- cord-006870-f5w6fw6q 829 14 were be VBD cord-006870-f5w6fw6q 829 15 found find VBN cord-006870-f5w6fw6q 829 16 to to TO cord-006870-f5w6fw6q 829 17 have have VB cord-006870-f5w6fw6q 829 18 MRI MRI NNP cord-006870-f5w6fw6q 829 19 evidence evidence NN cord-006870-f5w6fw6q 829 20 of of IN cord-006870-f5w6fw6q 829 21 cervical cervical JJ cord-006870-f5w6fw6q 829 22 instability instability NN cord-006870-f5w6fw6q 829 23 . . . cord-006870-f5w6fw6q 830 1 Notably notably RB cord-006870-f5w6fw6q 830 2 , , , cord-006870-f5w6fw6q 830 3 of of IN cord-006870-f5w6fw6q 830 4 the the DT cord-006870-f5w6fw6q 830 5 62 62 CD cord-006870-f5w6fw6q 830 6 patients patient NNS cord-006870-f5w6fw6q 830 7 who who WP cord-006870-f5w6fw6q 830 8 were be VBD cord-006870-f5w6fw6q 830 9 found find VBN cord-006870-f5w6fw6q 830 10 down down RP cord-006870-f5w6fw6q 830 11 , , , cord-006870-f5w6fw6q 830 12 there there EX cord-006870-f5w6fw6q 830 13 was be VBD cord-006870-f5w6fw6q 830 14 only only RB cord-006870-f5w6fw6q 830 15 one one CD cord-006870-f5w6fw6q 830 16 instance instance NN cord-006870-f5w6fw6q 830 17 where where WRB cord-006870-f5w6fw6q 830 18 the the DT cord-006870-f5w6fw6q 830 19 MRI MRI NNP cord-006870-f5w6fw6q 830 20 demonstrated demonstrate VBD cord-006870-f5w6fw6q 830 21 instability instability NN cord-006870-f5w6fw6q 830 22 . . . cord-006870-f5w6fw6q 831 1 That that DT cord-006870-f5w6fw6q 831 2 patient patient NN cord-006870-f5w6fw6q 831 3 had have VBD cord-006870-f5w6fw6q 831 4 extensive extensive JJ cord-006870-f5w6fw6q 831 5 facial facial JJ cord-006870-f5w6fw6q 831 6 injuries injury NNS cord-006870-f5w6fw6q 831 7 suggestive suggestive JJ cord-006870-f5w6fw6q 831 8 of of IN cord-006870-f5w6fw6q 831 9 an an DT cord-006870-f5w6fw6q 831 10 unwitnessed unwitnessed JJ cord-006870-f5w6fw6q 831 11 fall fall NN cord-006870-f5w6fw6q 831 12 . . . cord-006870-f5w6fw6q 832 1 In in IN cord-006870-f5w6fw6q 832 2 the the DT cord-006870-f5w6fw6q 832 3 40 40 CD cord-006870-f5w6fw6q 832 4 patients patient NNS cord-006870-f5w6fw6q 832 5 that that WDT cord-006870-f5w6fw6q 832 6 were be VBD cord-006870-f5w6fw6q 832 7 found find VBN cord-006870-f5w6fw6q 832 8 down down RP cord-006870-f5w6fw6q 832 9 with with IN cord-006870-f5w6fw6q 832 10 no no DT cord-006870-f5w6fw6q 832 11 history history NN cord-006870-f5w6fw6q 832 12 or or CC cord-006870-f5w6fw6q 832 13 evidence evidence NN cord-006870-f5w6fw6q 832 14 on on IN cord-006870-f5w6fw6q 832 15 physical physical JJ cord-006870-f5w6fw6q 832 16 exam exam NN cord-006870-f5w6fw6q 832 17 of of IN cord-006870-f5w6fw6q 832 18 trauma trauma NN cord-006870-f5w6fw6q 832 19 , , , cord-006870-f5w6fw6q 832 20 there there EX cord-006870-f5w6fw6q 832 21 was be VBD cord-006870-f5w6fw6q 832 22 no no DT cord-006870-f5w6fw6q 832 23 MRI MRI NNP cord-006870-f5w6fw6q 832 24 instability instability NN cord-006870-f5w6fw6q 832 25 . . . cord-006870-f5w6fw6q 833 1 For for IN cord-006870-f5w6fw6q 833 2 patients patient NNS cord-006870-f5w6fw6q 833 3 that that WDT cord-006870-f5w6fw6q 833 4 are be VBP cord-006870-f5w6fw6q 833 5 found find VBN cord-006870-f5w6fw6q 833 6 down down RP cord-006870-f5w6fw6q 833 7 without without IN cord-006870-f5w6fw6q 833 8 any any DT cord-006870-f5w6fw6q 833 9 history history NN cord-006870-f5w6fw6q 833 10 or or CC cord-006870-f5w6fw6q 833 11 evidence evidence NN cord-006870-f5w6fw6q 833 12 on on IN cord-006870-f5w6fw6q 833 13 physical physical JJ cord-006870-f5w6fw6q 833 14 exam exam NN cord-006870-f5w6fw6q 833 15 of of IN cord-006870-f5w6fw6q 833 16 trauma trauma NN cord-006870-f5w6fw6q 833 17 , , , cord-006870-f5w6fw6q 833 18 a a DT cord-006870-f5w6fw6q 833 19 CT CT NNP cord-006870-f5w6fw6q 833 20 of of IN cord-006870-f5w6fw6q 833 21 the the DT cord-006870-f5w6fw6q 833 22 cervical cervical JJ cord-006870-f5w6fw6q 833 23 spine spine NN cord-006870-f5w6fw6q 833 24 is be VBZ cord-006870-f5w6fw6q 833 25 likely likely RB cord-006870-f5w6fw6q 833 26 sufficient sufficient JJ cord-006870-f5w6fw6q 833 27 for for IN cord-006870-f5w6fw6q 833 28 cervical cervical JJ cord-006870-f5w6fw6q 833 29 spinal spinal JJ cord-006870-f5w6fw6q 833 30 clearance clearance NN cord-006870-f5w6fw6q 833 31 . . . cord-006870-f5w6fw6q 834 1 Acute acute JJ cord-006870-f5w6fw6q 834 2 subdural subdural JJ cord-006870-f5w6fw6q 834 3 hematoma hematoma NN cord-006870-f5w6fw6q 834 4 ( ( -LRB- cord-006870-f5w6fw6q 834 5 ASDH ASDH NNP cord-006870-f5w6fw6q 834 6 ) ) -RRB- cord-006870-f5w6fw6q 834 7 represents represent VBZ cord-006870-f5w6fw6q 834 8 a a DT cord-006870-f5w6fw6q 834 9 major major JJ cord-006870-f5w6fw6q 834 10 clinical clinical JJ cord-006870-f5w6fw6q 834 11 entity entity NN cord-006870-f5w6fw6q 834 12 in in IN cord-006870-f5w6fw6q 834 13 severe severe JJ cord-006870-f5w6fw6q 834 14 traumatic traumatic JJ cord-006870-f5w6fw6q 834 15 brain brain NN cord-006870-f5w6fw6q 834 16 ( ( -LRB- cord-006870-f5w6fw6q 834 17 sTBI stbi NN cord-006870-f5w6fw6q 834 18 ) ) -RRB- cord-006870-f5w6fw6q 834 19 , , , cord-006870-f5w6fw6q 834 20 approximately approximately RB cord-006870-f5w6fw6q 834 21 60 60 CD cord-006870-f5w6fw6q 834 22 % % NN cord-006870-f5w6fw6q 834 23 are be VBP cord-006870-f5w6fw6q 834 24 accompanied accompany VBN cord-006870-f5w6fw6q 834 25 by by IN cord-006870-f5w6fw6q 834 26 various various JJ cord-006870-f5w6fw6q 834 27 extents extent NNS cord-006870-f5w6fw6q 834 28 of of IN cord-006870-f5w6fw6q 834 29 ASDH ASDH NNP cord-006870-f5w6fw6q 834 30 . . . cord-006870-f5w6fw6q 835 1 STBI STBI NNP cord-006870-f5w6fw6q 835 2 has have VBZ cord-006870-f5w6fw6q 835 3 been be VBN cord-006870-f5w6fw6q 835 4 reported report VBN cord-006870-f5w6fw6q 835 5 to to TO cord-006870-f5w6fw6q 835 6 cause cause VB cord-006870-f5w6fw6q 835 7 cerebral cerebral JJ cord-006870-f5w6fw6q 835 8 circulatory circulatory JJ cord-006870-f5w6fw6q 835 9 disturbances disturbance NNS cord-006870-f5w6fw6q 835 10 at at IN cord-006870-f5w6fw6q 835 11 an an DT cord-006870-f5w6fw6q 835 12 acute acute JJ cord-006870-f5w6fw6q 835 13 stage stage NN cord-006870-f5w6fw6q 835 14 and and CC cord-006870-f5w6fw6q 835 15 had have VBD cord-006870-f5w6fw6q 835 16 the the DT cord-006870-f5w6fw6q 835 17 worst bad JJS cord-006870-f5w6fw6q 835 18 circulatory circulatory JJ cord-006870-f5w6fw6q 835 19 disturbance disturbance NN cord-006870-f5w6fw6q 835 20 among among IN cord-006870-f5w6fw6q 835 21 sTBI stbi NN cord-006870-f5w6fw6q 835 22 . . . cord-006870-f5w6fw6q 836 1 In in IN cord-006870-f5w6fw6q 836 2 this this DT cord-006870-f5w6fw6q 836 3 study study NN cord-006870-f5w6fw6q 836 4 , , , cord-006870-f5w6fw6q 836 5 we -PRON- PRP cord-006870-f5w6fw6q 836 6 focused focus VBD cord-006870-f5w6fw6q 836 7 on on IN cord-006870-f5w6fw6q 836 8 the the DT cord-006870-f5w6fw6q 836 9 cerebral cerebral JJ cord-006870-f5w6fw6q 836 10 circulation circulation NN cord-006870-f5w6fw6q 836 11 of of IN cord-006870-f5w6fw6q 836 12 ASDH ASDH NNP cord-006870-f5w6fw6q 836 13 , , , cord-006870-f5w6fw6q 836 14 evaluated evaluate VBD cord-006870-f5w6fw6q 836 15 the the DT cord-006870-f5w6fw6q 836 16 absolute absolute JJ cord-006870-f5w6fw6q 836 17 left left JJ cord-006870-f5w6fw6q 836 18 - - HYPH cord-006870-f5w6fw6q 836 19 right right JJ cord-006870-f5w6fw6q 836 20 difference difference NN cord-006870-f5w6fw6q 836 21 between between IN cord-006870-f5w6fw6q 836 22 cerebral cerebral JJ cord-006870-f5w6fw6q 836 23 hemispheres hemisphere NNS cord-006870-f5w6fw6q 836 24 and and CC cord-006870-f5w6fw6q 836 25 compared compare VBD cord-006870-f5w6fw6q 836 26 the the DT cord-006870-f5w6fw6q 836 27 cerebral cerebral JJ cord-006870-f5w6fw6q 836 28 circulation circulation NN cord-006870-f5w6fw6q 836 29 between between IN cord-006870-f5w6fw6q 836 30 the the DT cord-006870-f5w6fw6q 836 31 favorable favorable JJ cord-006870-f5w6fw6q 836 32 outcome outcome NN cord-006870-f5w6fw6q 836 33 group group NN cord-006870-f5w6fw6q 836 34 and and CC cord-006870-f5w6fw6q 836 35 the the DT cord-006870-f5w6fw6q 836 36 unfavorable unfavorable JJ cord-006870-f5w6fw6q 836 37 group group NN cord-006870-f5w6fw6q 836 38 . . . cord-006870-f5w6fw6q 837 1 We -PRON- PRP cord-006870-f5w6fw6q 837 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 837 3 reviewed review VBD cord-006870-f5w6fw6q 837 4 31 31 CD cord-006870-f5w6fw6q 837 5 patients patient NNS cord-006870-f5w6fw6q 837 6 with with IN cord-006870-f5w6fw6q 837 7 ASDH ASDH NNP cord-006870-f5w6fw6q 837 8 . . . cord-006870-f5w6fw6q 838 1 They -PRON- PRP cord-006870-f5w6fw6q 838 2 were be VBD cord-006870-f5w6fw6q 838 3 admitted admit VBN cord-006870-f5w6fw6q 838 4 to to IN cord-006870-f5w6fw6q 838 5 our -PRON- PRP$ cord-006870-f5w6fw6q 838 6 hospital hospital NN cord-006870-f5w6fw6q 838 7 from from IN cord-006870-f5w6fw6q 838 8 2002 2002 CD cord-006870-f5w6fw6q 838 9 to2011 to2011 NNP cord-006870-f5w6fw6q 838 10 . . . cord-006870-f5w6fw6q 839 1 In in IN cord-006870-f5w6fw6q 839 2 these these DT cord-006870-f5w6fw6q 839 3 patients patient NNS cord-006870-f5w6fw6q 839 4 , , , cord-006870-f5w6fw6q 839 5 we -PRON- PRP cord-006870-f5w6fw6q 839 6 simultaneously simultaneously RB cord-006870-f5w6fw6q 839 7 performed perform VBD cord-006870-f5w6fw6q 839 8 xenon xenon NN cord-006870-f5w6fw6q 839 9 - - HYPH cord-006870-f5w6fw6q 839 10 computed compute VBN cord-006870-f5w6fw6q 839 11 tomography tomography NN cord-006870-f5w6fw6q 839 12 ( ( -LRB- cord-006870-f5w6fw6q 839 13 Xe Xe NNP cord-006870-f5w6fw6q 839 14 - - HYPH cord-006870-f5w6fw6q 839 15 CT CT NNP cord-006870-f5w6fw6q 839 16 ) ) -RRB- cord-006870-f5w6fw6q 839 17 and and CC cord-006870-f5w6fw6q 839 18 perfusion perfusion NN cord-006870-f5w6fw6q 839 19 CT CT NNP cord-006870-f5w6fw6q 839 20 to to TO cord-006870-f5w6fw6q 839 21 evaluate evaluate VB cord-006870-f5w6fw6q 839 22 the the DT cord-006870-f5w6fw6q 839 23 cerebral cerebral JJ cord-006870-f5w6fw6q 839 24 circulation circulation NN cord-006870-f5w6fw6q 839 25 on on IN cord-006870-f5w6fw6q 839 26 post post JJ cord-006870-f5w6fw6q 839 27 - - JJ cord-006870-f5w6fw6q 839 28 injury injury JJ cord-006870-f5w6fw6q 839 29 days day NNS cord-006870-f5w6fw6q 839 30 1 1 CD cord-006870-f5w6fw6q 839 31 - - SYM cord-006870-f5w6fw6q 839 32 3 3 CD cord-006870-f5w6fw6q 839 33 . . . cord-006870-f5w6fw6q 840 1 We -PRON- PRP cord-006870-f5w6fw6q 840 2 measured measure VBD cord-006870-f5w6fw6q 840 3 CBF CBF NNP cord-006870-f5w6fw6q 840 4 using use VBG cord-006870-f5w6fw6q 840 5 Xe Xe NNP cord-006870-f5w6fw6q 840 6 - - HYPH cord-006870-f5w6fw6q 840 7 CT CT NNP cord-006870-f5w6fw6q 840 8 and and CC cord-006870-f5w6fw6q 840 9 mean mean VB cord-006870-f5w6fw6q 840 10 transit transit NN cord-006870-f5w6fw6q 840 11 time time NN cord-006870-f5w6fw6q 840 12 using use VBG cord-006870-f5w6fw6q 840 13 perfusion perfusion NN cord-006870-f5w6fw6q 840 14 CT CT NNP cord-006870-f5w6fw6q 840 15 and and CC cord-006870-f5w6fw6q 840 16 calculated calculate VBD cord-006870-f5w6fw6q 840 17 the the DT cord-006870-f5w6fw6q 840 18 cerebral cerebral JJ cord-006870-f5w6fw6q 840 19 blood blood NN cord-006870-f5w6fw6q 840 20 volume volume NN cord-006870-f5w6fw6q 840 21 ( ( -LRB- cord-006870-f5w6fw6q 840 22 CBV CBV NNP cord-006870-f5w6fw6q 840 23 ) ) -RRB- cord-006870-f5w6fw6q 840 24 . . . cord-006870-f5w6fw6q 841 1 A a DT cord-006870-f5w6fw6q 841 2 significant significant JJ cord-006870-f5w6fw6q 841 3 absolute absolute JJ cord-006870-f5w6fw6q 841 4 difference difference NN cord-006870-f5w6fw6q 841 5 in in IN cord-006870-f5w6fw6q 841 6 cerebral cerebral JJ cord-006870-f5w6fw6q 841 7 circulation circulation NN cord-006870-f5w6fw6q 841 8 between between IN cord-006870-f5w6fw6q 841 9 the the DT cord-006870-f5w6fw6q 841 10 hemispheres hemisphere NNS cord-006870-f5w6fw6q 841 11 among among IN cord-006870-f5w6fw6q 841 12 different different JJ cord-006870-f5w6fw6q 841 13 types type NNS cord-006870-f5w6fw6q 841 14 of of IN cord-006870-f5w6fw6q 841 15 TBI TBI NNP cord-006870-f5w6fw6q 841 16 was be VBD cord-006870-f5w6fw6q 841 17 observed observe VBN cord-006870-f5w6fw6q 841 18 in in IN cord-006870-f5w6fw6q 841 19 MTT MTT NNP cord-006870-f5w6fw6q 841 20 . . . cord-006870-f5w6fw6q 842 1 There there EX cord-006870-f5w6fw6q 842 2 was be VBD cord-006870-f5w6fw6q 842 3 no no DT cord-006870-f5w6fw6q 842 4 significant significant JJ cord-006870-f5w6fw6q 842 5 difference difference NN cord-006870-f5w6fw6q 842 6 in in IN cord-006870-f5w6fw6q 842 7 these these DT cord-006870-f5w6fw6q 842 8 parameters parameter NNS cord-006870-f5w6fw6q 842 9 between between IN cord-006870-f5w6fw6q 842 10 left left JJ cord-006870-f5w6fw6q 842 11 - - HYPH cord-006870-f5w6fw6q 842 12 right right JJ cord-006870-f5w6fw6q 842 13 hemispheres hemisphere NNS cord-006870-f5w6fw6q 842 14 with with IN cord-006870-f5w6fw6q 842 15 ASDH ASDH NNP cord-006870-f5w6fw6q 842 16 among among IN cord-006870-f5w6fw6q 842 17 the the DT cord-006870-f5w6fw6q 842 18 favorable favorable JJ cord-006870-f5w6fw6q 842 19 outcome outcome NN cord-006870-f5w6fw6q 842 20 group group NN cord-006870-f5w6fw6q 842 21 and and CC cord-006870-f5w6fw6q 842 22 unfavorable unfavorable JJ cord-006870-f5w6fw6q 842 23 group group NN cord-006870-f5w6fw6q 842 24 . . . cord-006870-f5w6fw6q 843 1 Although although IN cord-006870-f5w6fw6q 843 2 there there EX cord-006870-f5w6fw6q 843 3 was be VBD cord-006870-f5w6fw6q 843 4 no no DT cord-006870-f5w6fw6q 843 5 significant significant JJ cord-006870-f5w6fw6q 843 6 difference difference NN cord-006870-f5w6fw6q 843 7 in in IN cord-006870-f5w6fw6q 843 8 age age NN cord-006870-f5w6fw6q 843 9 , , , cord-006870-f5w6fw6q 843 10 GCS GCS NNP cord-006870-f5w6fw6q 843 11 at at IN cord-006870-f5w6fw6q 843 12 the the DT cord-006870-f5w6fw6q 843 13 onset onset NN cord-006870-f5w6fw6q 843 14 of of IN cord-006870-f5w6fw6q 843 15 treatment treatment NN cord-006870-f5w6fw6q 843 16 , , , cord-006870-f5w6fw6q 843 17 CBF CBF NNP cord-006870-f5w6fw6q 843 18 and and CC cord-006870-f5w6fw6q 843 19 CBV CBV NNP cord-006870-f5w6fw6q 843 20 , , , cord-006870-f5w6fw6q 843 21 there there EX cord-006870-f5w6fw6q 843 22 was be VBD cord-006870-f5w6fw6q 843 23 significant significant JJ cord-006870-f5w6fw6q 843 24 difference difference NN cord-006870-f5w6fw6q 843 25 only only RB cord-006870-f5w6fw6q 843 26 in in IN cord-006870-f5w6fw6q 843 27 MTT MTT NNP cord-006870-f5w6fw6q 843 28 between between IN cord-006870-f5w6fw6q 843 29 the the DT cord-006870-f5w6fw6q 843 30 favorable favorable JJ cord-006870-f5w6fw6q 843 31 outcome outcome NN cord-006870-f5w6fw6q 843 32 group group NN cord-006870-f5w6fw6q 843 33 and and CC cord-006870-f5w6fw6q 843 34 unfavorable unfavorable JJ cord-006870-f5w6fw6q 843 35 group group NN cord-006870-f5w6fw6q 843 36 . . . cord-006870-f5w6fw6q 844 1 The the DT cord-006870-f5w6fw6q 844 2 circulatory circulatory JJ cord-006870-f5w6fw6q 844 3 disturbance disturbance NN cord-006870-f5w6fw6q 844 4 in in IN cord-006870-f5w6fw6q 844 5 patients patient NNS cord-006870-f5w6fw6q 844 6 with with IN cord-006870-f5w6fw6q 844 7 ASDH ASDH NNP cord-006870-f5w6fw6q 844 8 occurs occur VBZ cord-006870-f5w6fw6q 844 9 diffusely diffusely RB cord-006870-f5w6fw6q 844 10 despite despite IN cord-006870-f5w6fw6q 844 11 the the DT cord-006870-f5w6fw6q 844 12 focal focal JJ cord-006870-f5w6fw6q 844 13 injury injury NN cord-006870-f5w6fw6q 844 14 . . . cord-006870-f5w6fw6q 845 1 Additionally additionally RB cord-006870-f5w6fw6q 845 2 , , , cord-006870-f5w6fw6q 845 3 in in IN cord-006870-f5w6fw6q 845 4 unfavorable unfavorable JJ cord-006870-f5w6fw6q 845 5 patients patient NNS cord-006870-f5w6fw6q 845 6 , , , cord-006870-f5w6fw6q 845 7 the the DT cord-006870-f5w6fw6q 845 8 circulatory circulatory JJ cord-006870-f5w6fw6q 845 9 disturbance disturbance NN cord-006870-f5w6fw6q 845 10 is be VBZ cord-006870-f5w6fw6q 845 11 worse bad JJR cord-006870-f5w6fw6q 845 12 than than IN cord-006870-f5w6fw6q 845 13 in in IN cord-006870-f5w6fw6q 845 14 favorable favorable JJ cord-006870-f5w6fw6q 845 15 patients patient NNS cord-006870-f5w6fw6q 845 16 . . . cord-006870-f5w6fw6q 846 1 Because because IN cord-006870-f5w6fw6q 846 2 ASDH ASDH NNP cord-006870-f5w6fw6q 846 3 suffered suffer VBD cord-006870-f5w6fw6q 846 4 ischemia ischemia NN cord-006870-f5w6fw6q 846 5 more more RBR cord-006870-f5w6fw6q 846 6 than than IN cord-006870-f5w6fw6q 846 7 other other JJ cord-006870-f5w6fw6q 846 8 types type NNS cord-006870-f5w6fw6q 846 9 of of IN cord-006870-f5w6fw6q 846 10 sTBI stbi NN cord-006870-f5w6fw6q 846 11 , , , cord-006870-f5w6fw6q 846 12 we -PRON- PRP cord-006870-f5w6fw6q 846 13 had have VBD cord-006870-f5w6fw6q 846 14 to to TO cord-006870-f5w6fw6q 846 15 perform perform VB cord-006870-f5w6fw6q 846 16 not not RB cord-006870-f5w6fw6q 846 17 only only JJ cord-006870-f5w6fw6q 846 18 removal removal NN cord-006870-f5w6fw6q 846 19 of of IN cord-006870-f5w6fw6q 846 20 the the DT cord-006870-f5w6fw6q 846 21 occupying occupy VBG cord-006870-f5w6fw6q 846 22 lesions lesion NNS cord-006870-f5w6fw6q 846 23 , , , cord-006870-f5w6fw6q 846 24 but but CC cord-006870-f5w6fw6q 846 25 also also RB cord-006870-f5w6fw6q 846 26 neurointensive neurointensive JJ cord-006870-f5w6fw6q 846 27 care care NN cord-006870-f5w6fw6q 846 28 , , , cord-006870-f5w6fw6q 846 29 including include VBG cord-006870-f5w6fw6q 846 30 whole whole JJ cord-006870-f5w6fw6q 846 31 - - HYPH cord-006870-f5w6fw6q 846 32 body body NN cord-006870-f5w6fw6q 846 33 management management NN cord-006870-f5w6fw6q 846 34 and and CC cord-006870-f5w6fw6q 846 35 hypothermia hypothermia NN cord-006870-f5w6fw6q 846 36 therapy therapy NN cord-006870-f5w6fw6q 846 37 for for IN cord-006870-f5w6fw6q 846 38 the the DT cord-006870-f5w6fw6q 846 39 ischemic ischemic JJ cord-006870-f5w6fw6q 846 40 brain brain NN cord-006870-f5w6fw6q 846 41 after after IN cord-006870-f5w6fw6q 846 42 surgery surgery NN cord-006870-f5w6fw6q 846 43 . . . cord-006870-f5w6fw6q 847 1 We -PRON- PRP cord-006870-f5w6fw6q 847 2 have have VBP cord-006870-f5w6fw6q 847 3 to to TO cord-006870-f5w6fw6q 847 4 adopt adopt VB cord-006870-f5w6fw6q 847 5 a a DT cord-006870-f5w6fw6q 847 6 treatment treatment NN cord-006870-f5w6fw6q 847 7 strategy strategy NN cord-006870-f5w6fw6q 847 8 appropriate appropriate JJ cord-006870-f5w6fw6q 847 9 to to IN cord-006870-f5w6fw6q 847 10 the the DT cord-006870-f5w6fw6q 847 11 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 847 12 of of IN cord-006870-f5w6fw6q 847 13 the the DT cord-006870-f5w6fw6q 847 14 different different JJ cord-006870-f5w6fw6q 847 15 TBI TBI NNP cord-006870-f5w6fw6q 847 16 types type NNS cord-006870-f5w6fw6q 847 17 . . . cord-006870-f5w6fw6q 848 1 Kcentra Kcentra NNP cord-006870-f5w6fw6q 848 2 is be VBZ cord-006870-f5w6fw6q 848 3 4-factor 4-factor CD cord-006870-f5w6fw6q 848 4 prothrombin prothrombin NN cord-006870-f5w6fw6q 848 5 complex complex NN cord-006870-f5w6fw6q 848 6 concentrate concentrate NN cord-006870-f5w6fw6q 848 7 that that WDT cord-006870-f5w6fw6q 848 8 is be VBZ cord-006870-f5w6fw6q 848 9 FDA FDA NNP cord-006870-f5w6fw6q 848 10 approved approve VBN cord-006870-f5w6fw6q 848 11 for for IN cord-006870-f5w6fw6q 848 12 reversal reversal NN cord-006870-f5w6fw6q 848 13 of of IN cord-006870-f5w6fw6q 848 14 warfarin warfarin NN cord-006870-f5w6fw6q 848 15 . . . cord-006870-f5w6fw6q 849 1 There there EX cord-006870-f5w6fw6q 849 2 is be VBZ cord-006870-f5w6fw6q 849 3 limited limited JJ cord-006870-f5w6fw6q 849 4 research research NN cord-006870-f5w6fw6q 849 5 describing describe VBG cord-006870-f5w6fw6q 849 6 the the DT cord-006870-f5w6fw6q 849 7 use use NN cord-006870-f5w6fw6q 849 8 of of IN cord-006870-f5w6fw6q 849 9 Kcentra Kcentra NNP cord-006870-f5w6fw6q 849 10 for for IN cord-006870-f5w6fw6q 849 11 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 849 12 in in IN cord-006870-f5w6fw6q 849 13 the the DT cord-006870-f5w6fw6q 849 14 setting setting NN cord-006870-f5w6fw6q 849 15 of of IN cord-006870-f5w6fw6q 849 16 traumatic traumatic JJ cord-006870-f5w6fw6q 849 17 intracranial intracranial JJ cord-006870-f5w6fw6q 849 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 849 19 . . . cord-006870-f5w6fw6q 850 1 Here here RB cord-006870-f5w6fw6q 850 2 , , , cord-006870-f5w6fw6q 850 3 we -PRON- PRP cord-006870-f5w6fw6q 850 4 show show VBP cord-006870-f5w6fw6q 850 5 the the DT cord-006870-f5w6fw6q 850 6 largest large JJS cord-006870-f5w6fw6q 850 7 ever ever RB cord-006870-f5w6fw6q 850 8 retrospective retrospective JJ cord-006870-f5w6fw6q 850 9 review review NN cord-006870-f5w6fw6q 850 10 for for IN cord-006870-f5w6fw6q 850 11 the the DT cord-006870-f5w6fw6q 850 12 use use NN cord-006870-f5w6fw6q 850 13 of of IN cord-006870-f5w6fw6q 850 14 Kcentra Kcentra NNP cord-006870-f5w6fw6q 850 15 in in IN cord-006870-f5w6fw6q 850 16 the the DT cord-006870-f5w6fw6q 850 17 setting setting NN cord-006870-f5w6fw6q 850 18 of of IN cord-006870-f5w6fw6q 850 19 traumatic traumatic JJ cord-006870-f5w6fw6q 850 20 intracranial intracranial JJ cord-006870-f5w6fw6q 850 21 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 850 22 . . . cord-006870-f5w6fw6q 851 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 851 2 chart chart NN cord-006870-f5w6fw6q 851 3 review review NN cord-006870-f5w6fw6q 851 4 was be VBD cord-006870-f5w6fw6q 851 5 performed perform VBN cord-006870-f5w6fw6q 851 6 from from IN cord-006870-f5w6fw6q 851 7 2013 2013 CD cord-006870-f5w6fw6q 851 8 - - SYM cord-006870-f5w6fw6q 851 9 2016 2016 CD cord-006870-f5w6fw6q 851 10 for for IN cord-006870-f5w6fw6q 851 11 patients patient NNS cord-006870-f5w6fw6q 851 12 with with IN cord-006870-f5w6fw6q 851 13 intracranial intracranial JJ cord-006870-f5w6fw6q 851 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 851 15 who who WP cord-006870-f5w6fw6q 851 16 presented present VBD cord-006870-f5w6fw6q 851 17 to to IN cord-006870-f5w6fw6q 851 18 the the DT cord-006870-f5w6fw6q 851 19 R R NNP cord-006870-f5w6fw6q 851 20 Adams Adams NNP cord-006870-f5w6fw6q 851 21 Cowley Cowley NNP cord-006870-f5w6fw6q 851 22 Shock Shock NNP cord-006870-f5w6fw6q 851 23 Trauma Trauma NNP cord-006870-f5w6fw6q 851 24 Center Center NNP cord-006870-f5w6fw6q 851 25 . . . cord-006870-f5w6fw6q 852 1 Patients patient NNS cord-006870-f5w6fw6q 852 2 who who WP cord-006870-f5w6fw6q 852 3 received receive VBD cord-006870-f5w6fw6q 852 4 Kcentra Kcentra NNP cord-006870-f5w6fw6q 852 5 were be VBD cord-006870-f5w6fw6q 852 6 identified identify VBN cord-006870-f5w6fw6q 852 7 . . . cord-006870-f5w6fw6q 853 1 Basic basic JJ cord-006870-f5w6fw6q 853 2 clinical clinical JJ cord-006870-f5w6fw6q 853 3 information information NN cord-006870-f5w6fw6q 853 4 was be VBD cord-006870-f5w6fw6q 853 5 obtained obtain VBN cord-006870-f5w6fw6q 853 6 including include VBG cord-006870-f5w6fw6q 853 7 cardiac cardiac JJ cord-006870-f5w6fw6q 853 8 / / SYM cord-006870-f5w6fw6q 853 9 stroke stroke NN cord-006870-f5w6fw6q 853 10 history history NN cord-006870-f5w6fw6q 853 11 , , , cord-006870-f5w6fw6q 853 12 blood blood NN cord-006870-f5w6fw6q 853 13 pressure pressure NN cord-006870-f5w6fw6q 853 14 , , , cord-006870-f5w6fw6q 853 15 Glasgow Glasgow NNP cord-006870-f5w6fw6q 853 16 Coma Coma NNP cord-006870-f5w6fw6q 853 17 Score Score NNP cord-006870-f5w6fw6q 853 18 , , , cord-006870-f5w6fw6q 853 19 medication medication NN cord-006870-f5w6fw6q 853 20 history history NN cord-006870-f5w6fw6q 853 21 , , , cord-006870-f5w6fw6q 853 22 and and CC cord-006870-f5w6fw6q 853 23 categorization categorization NN cord-006870-f5w6fw6q 853 24 of of IN cord-006870-f5w6fw6q 853 25 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 853 26 . . . cord-006870-f5w6fw6q 854 1 Pre pre JJ cord-006870-f5w6fw6q 854 2 and and CC cord-006870-f5w6fw6q 854 3 post post VB cord-006870-f5w6fw6q 854 4 INR INR NNP cord-006870-f5w6fw6q 854 5 level level NN cord-006870-f5w6fw6q 854 6 was be VBD cord-006870-f5w6fw6q 854 7 assessed assess VBN cord-006870-f5w6fw6q 854 8 . . . cord-006870-f5w6fw6q 855 1 Hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 855 2 expansion expansion NN cord-006870-f5w6fw6q 855 3 was be VBD cord-006870-f5w6fw6q 855 4 assessed assess VBN cord-006870-f5w6fw6q 855 5 with with IN cord-006870-f5w6fw6q 855 6 CT CT NNP cord-006870-f5w6fw6q 855 7 scan scan VB cord-006870-f5w6fw6q 855 8 up up IN cord-006870-f5w6fw6q 855 9 to to TO cord-006870-f5w6fw6q 855 10 up up IN cord-006870-f5w6fw6q 855 11 to to TO cord-006870-f5w6fw6q 855 12 24 24 CD cord-006870-f5w6fw6q 855 13 hours hour NNS cord-006870-f5w6fw6q 855 14 . . . cord-006870-f5w6fw6q 856 1 Disposition disposition NN cord-006870-f5w6fw6q 856 2 and and CC cord-006870-f5w6fw6q 856 3 thromboembolic thromboembolic JJ cord-006870-f5w6fw6q 856 4 events event NNS cord-006870-f5w6fw6q 856 5 were be VBD cord-006870-f5w6fw6q 856 6 recorded record VBN cord-006870-f5w6fw6q 856 7 . . . cord-006870-f5w6fw6q 857 1 Forty forty CD cord-006870-f5w6fw6q 857 2 - - HYPH cord-006870-f5w6fw6q 857 3 four four CD cord-006870-f5w6fw6q 857 4 patients patient NNS cord-006870-f5w6fw6q 857 5 were be VBD cord-006870-f5w6fw6q 857 6 identified identify VBN cord-006870-f5w6fw6q 857 7 as as IN cord-006870-f5w6fw6q 857 8 receiving receive VBG cord-006870-f5w6fw6q 857 9 Kcentra Kcentra NNP cord-006870-f5w6fw6q 857 10 in in IN cord-006870-f5w6fw6q 857 11 the the DT cord-006870-f5w6fw6q 857 12 setting setting NN cord-006870-f5w6fw6q 857 13 of of IN cord-006870-f5w6fw6q 857 14 traumatic traumatic JJ cord-006870-f5w6fw6q 857 15 intracranial intracranial JJ cord-006870-f5w6fw6q 857 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 857 17 . . . cord-006870-f5w6fw6q 858 1 Pre pre JJ cord-006870-f5w6fw6q 858 2 and and CC cord-006870-f5w6fw6q 858 3 post post VB cord-006870-f5w6fw6q 858 4 Kcentra Kcentra NNP cord-006870-f5w6fw6q 858 5 dosing dose VBG cord-006870-f5w6fw6q 858 6 INR INR NNP cord-006870-f5w6fw6q 858 7 was be VBD cord-006870-f5w6fw6q 858 8 found find VBN cord-006870-f5w6fw6q 858 9 to to TO cord-006870-f5w6fw6q 858 10 be be VB cord-006870-f5w6fw6q 858 11 significantly significantly RB cord-006870-f5w6fw6q 858 12 different different JJ cord-006870-f5w6fw6q 858 13 ( ( -LRB- cord-006870-f5w6fw6q 858 14 p<0.001 p<0.001 JJ cord-006870-f5w6fw6q 858 15 ) ) -RRB- cord-006870-f5w6fw6q 858 16 across across IN cord-006870-f5w6fw6q 858 17 the the DT cord-006870-f5w6fw6q 858 18 two two CD cord-006870-f5w6fw6q 858 19 groups group NNS cord-006870-f5w6fw6q 858 20 assessed assess VBN cord-006870-f5w6fw6q 858 21 ( ( -LRB- cord-006870-f5w6fw6q 858 22 warfarin warfarin NNP cord-006870-f5w6fw6q 858 23 and and CC cord-006870-f5w6fw6q 858 24 TBI TBI NNP cord-006870-f5w6fw6q 858 25 / / SYM cord-006870-f5w6fw6q 858 26 NOAC NOAC NNP cord-006870-f5w6fw6q 858 27 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 858 28 ) ) -RRB- cord-006870-f5w6fw6q 858 29 . . . cord-006870-f5w6fw6q 859 1 Seventeen seventeen CD cord-006870-f5w6fw6q 859 2 patients patient NNS cord-006870-f5w6fw6q 859 3 ( ( -LRB- cord-006870-f5w6fw6q 859 4 38.6 38.6 CD cord-006870-f5w6fw6q 859 5 % % NN cord-006870-f5w6fw6q 859 6 ) ) -RRB- cord-006870-f5w6fw6q 859 7 had have VBD cord-006870-f5w6fw6q 859 8 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 859 9 expansion expansion NN cord-006870-f5w6fw6q 859 10 as as IN cord-006870-f5w6fw6q 859 11 determined determine VBN cord-006870-f5w6fw6q 859 12 on on IN cord-006870-f5w6fw6q 859 13 CT CT NNP cord-006870-f5w6fw6q 859 14 scan scan NN cord-006870-f5w6fw6q 859 15 . . . cord-006870-f5w6fw6q 860 1 Disposition Disposition NNP cord-006870-f5w6fw6q 860 2 ( ( -LRB- cord-006870-f5w6fw6q 860 3 home home NN cord-006870-f5w6fw6q 860 4 vs vs IN cord-006870-f5w6fw6q 860 5 rehab rehab NN cord-006870-f5w6fw6q 860 6 vs vs IN cord-006870-f5w6fw6q 860 7 death death NN cord-006870-f5w6fw6q 860 8 ) ) -RRB- cord-006870-f5w6fw6q 860 9 was be VBD cord-006870-f5w6fw6q 860 10 found find VBN cord-006870-f5w6fw6q 860 11 to to TO cord-006870-f5w6fw6q 860 12 have have VB cord-006870-f5w6fw6q 860 13 three three CD cord-006870-f5w6fw6q 860 14 significant significant JJ cord-006870-f5w6fw6q 860 15 variables variable NNS cord-006870-f5w6fw6q 860 16 : : : cord-006870-f5w6fw6q 860 17 history history NN cord-006870-f5w6fw6q 860 18 of of IN cord-006870-f5w6fw6q 860 19 stroke stroke NN cord-006870-f5w6fw6q 860 20 , , , cord-006870-f5w6fw6q 860 21 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 860 22 expansion expansion NN cord-006870-f5w6fw6q 860 23 , , , cord-006870-f5w6fw6q 860 24 and and CC cord-006870-f5w6fw6q 860 25 admission admission NN cord-006870-f5w6fw6q 860 26 Glasgow Glasgow NNP cord-006870-f5w6fw6q 860 27 Coma Coma NNP cord-006870-f5w6fw6q 860 28 Score Score NNP cord-006870-f5w6fw6q 860 29 . . . cord-006870-f5w6fw6q 861 1 Eight eight CD cord-006870-f5w6fw6q 861 2 patients patient NNS cord-006870-f5w6fw6q 861 3 ( ( -LRB- cord-006870-f5w6fw6q 861 4 18.2 18.2 CD cord-006870-f5w6fw6q 861 5 % % NN cord-006870-f5w6fw6q 861 6 ) ) -RRB- cord-006870-f5w6fw6q 861 7 were be VBD cord-006870-f5w6fw6q 861 8 found find VBN cord-006870-f5w6fw6q 861 9 to to TO cord-006870-f5w6fw6q 861 10 have have VB cord-006870-f5w6fw6q 861 11 thromboembolic thromboembolic JJ cord-006870-f5w6fw6q 861 12 events event NNS cord-006870-f5w6fw6q 861 13 . . . cord-006870-f5w6fw6q 862 1 Here here RB cord-006870-f5w6fw6q 862 2 , , , cord-006870-f5w6fw6q 862 3 we -PRON- PRP cord-006870-f5w6fw6q 862 4 show show VBP cord-006870-f5w6fw6q 862 5 the the DT cord-006870-f5w6fw6q 862 6 largest large JJS cord-006870-f5w6fw6q 862 7 retrospective retrospective JJ cord-006870-f5w6fw6q 862 8 review review NN cord-006870-f5w6fw6q 862 9 describing describe VBG cord-006870-f5w6fw6q 862 10 the the DT cord-006870-f5w6fw6q 862 11 clinical clinical JJ cord-006870-f5w6fw6q 862 12 use use NN cord-006870-f5w6fw6q 862 13 of of IN cord-006870-f5w6fw6q 862 14 Kcentra Kcentra NNP cord-006870-f5w6fw6q 862 15 for for IN cord-006870-f5w6fw6q 862 16 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 862 17 reversal reversal NN cord-006870-f5w6fw6q 862 18 in in IN cord-006870-f5w6fw6q 862 19 the the DT cord-006870-f5w6fw6q 862 20 setting setting NN cord-006870-f5w6fw6q 862 21 of of IN cord-006870-f5w6fw6q 862 22 intracranial intracranial JJ cord-006870-f5w6fw6q 862 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 862 24 . . . cord-006870-f5w6fw6q 863 1 Overall overall RB cord-006870-f5w6fw6q 863 2 , , , cord-006870-f5w6fw6q 863 3 Kcentra Kcentra NNP cord-006870-f5w6fw6q 863 4 is be VBZ cord-006870-f5w6fw6q 863 5 shown show VBN cord-006870-f5w6fw6q 863 6 to to TO cord-006870-f5w6fw6q 863 7 be be VB cord-006870-f5w6fw6q 863 8 a a DT cord-006870-f5w6fw6q 863 9 safe safe JJ cord-006870-f5w6fw6q 863 10 and and CC cord-006870-f5w6fw6q 863 11 effective effective JJ cord-006870-f5w6fw6q 863 12 drug drug NN cord-006870-f5w6fw6q 863 13 for for IN cord-006870-f5w6fw6q 863 14 the the DT cord-006870-f5w6fw6q 863 15 reversal reversal NN cord-006870-f5w6fw6q 863 16 INR INR NNP cord-006870-f5w6fw6q 863 17 . . . cord-006870-f5w6fw6q 864 1 Importantly importantly RB cord-006870-f5w6fw6q 864 2 , , , cord-006870-f5w6fw6q 864 3 our -PRON- PRP$ cord-006870-f5w6fw6q 864 4 reported report VBN cord-006870-f5w6fw6q 864 5 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 864 6 rate rate NN cord-006870-f5w6fw6q 864 7 of of IN cord-006870-f5w6fw6q 864 8 38.6 38.6 CD cord-006870-f5w6fw6q 864 9 % % NN cord-006870-f5w6fw6q 864 10 is be VBZ cord-006870-f5w6fw6q 864 11 lower low JJR cord-006870-f5w6fw6q 864 12 than than IN cord-006870-f5w6fw6q 864 13 established establish VBN cord-006870-f5w6fw6q 864 14 rates rate NNS cord-006870-f5w6fw6q 864 15 reported report VBN cord-006870-f5w6fw6q 864 16 in in IN cord-006870-f5w6fw6q 864 17 the the DT cord-006870-f5w6fw6q 864 18 literature literature NN cord-006870-f5w6fw6q 864 19 for for IN cord-006870-f5w6fw6q 864 20 warfarin warfarin NN cord-006870-f5w6fw6q 864 21 / / SYM cord-006870-f5w6fw6q 864 22 coagulopathic coagulopathic JJ cord-006870-f5w6fw6q 864 23 patients patient NNS cord-006870-f5w6fw6q 864 24 with with IN cord-006870-f5w6fw6q 864 25 intracerebral intracerebral JJ cord-006870-f5w6fw6q 864 26 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 864 27 ( ( -LRB- cord-006870-f5w6fw6q 864 28 50 50 CD cord-006870-f5w6fw6q 864 29 - - SYM cord-006870-f5w6fw6q 864 30 60 60 CD cord-006870-f5w6fw6q 864 31 % % NN cord-006870-f5w6fw6q 864 32 ) ) -RRB- cord-006870-f5w6fw6q 864 33 . . . cord-006870-f5w6fw6q 865 1 The the DT cord-006870-f5w6fw6q 865 2 prognostic prognostic JJ cord-006870-f5w6fw6q 865 3 importance importance NN cord-006870-f5w6fw6q 865 4 of of IN cord-006870-f5w6fw6q 865 5 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 865 6 expansion expansion NN cord-006870-f5w6fw6q 865 7 was be VBD cord-006870-f5w6fw6q 865 8 highlighted highlight VBN cord-006870-f5w6fw6q 865 9 in in IN cord-006870-f5w6fw6q 865 10 the the DT cord-006870-f5w6fw6q 865 11 disposition disposition NN cord-006870-f5w6fw6q 865 12 analysis analysis NN cord-006870-f5w6fw6q 865 13 which which WDT cord-006870-f5w6fw6q 865 14 showed show VBD cord-006870-f5w6fw6q 865 15 that that IN cord-006870-f5w6fw6q 865 16 zero zero CD cord-006870-f5w6fw6q 865 17 patients patient NNS cord-006870-f5w6fw6q 865 18 were be VBD cord-006870-f5w6fw6q 865 19 discharge discharge NN cord-006870-f5w6fw6q 865 20 home home RB cord-006870-f5w6fw6q 865 21 if if IN cord-006870-f5w6fw6q 865 22 there there EX cord-006870-f5w6fw6q 865 23 was be VBD cord-006870-f5w6fw6q 865 24 recorded record VBN cord-006870-f5w6fw6q 865 25 expansion expansion NN cord-006870-f5w6fw6q 865 26 . . . cord-006870-f5w6fw6q 865 27 _SP cord-006870-f5w6fw6q 866 1 Despite despite IN cord-006870-f5w6fw6q 866 2 the the DT cord-006870-f5w6fw6q 866 3 impact impact NN cord-006870-f5w6fw6q 866 4 of of IN cord-006870-f5w6fw6q 866 5 post post JJ cord-006870-f5w6fw6q 866 6 - - JJ cord-006870-f5w6fw6q 866 7 traumatic traumatic JJ cord-006870-f5w6fw6q 866 8 amnesia amnesia NN cord-006870-f5w6fw6q 866 9 ( ( -LRB- cord-006870-f5w6fw6q 866 10 PTA PTA NNP cord-006870-f5w6fw6q 866 11 ) ) -RRB- cord-006870-f5w6fw6q 866 12 duration duration NN cord-006870-f5w6fw6q 866 13 on on IN cord-006870-f5w6fw6q 866 14 long long JJ cord-006870-f5w6fw6q 866 15 - - HYPH cord-006870-f5w6fw6q 866 16 term term NN cord-006870-f5w6fw6q 866 17 functional functional JJ cord-006870-f5w6fw6q 866 18 outcome outcome NN cord-006870-f5w6fw6q 866 19 after after IN cord-006870-f5w6fw6q 866 20 traumatic traumatic JJ cord-006870-f5w6fw6q 866 21 brain brain NN cord-006870-f5w6fw6q 866 22 injury injury NN cord-006870-f5w6fw6q 866 23 ( ( -LRB- cord-006870-f5w6fw6q 866 24 TBI TBI NNP cord-006870-f5w6fw6q 866 25 ) ) -RRB- cord-006870-f5w6fw6q 866 26 , , , cord-006870-f5w6fw6q 866 27 radiologic radiologic JJ cord-006870-f5w6fw6q 866 28 predictors predictor NNS cord-006870-f5w6fw6q 866 29 of of IN cord-006870-f5w6fw6q 866 30 PTA PTA NNP cord-006870-f5w6fw6q 866 31 duration duration NN cord-006870-f5w6fw6q 866 32 are be VBP cord-006870-f5w6fw6q 866 33 lacking lack VBG cord-006870-f5w6fw6q 866 34 . . . cord-006870-f5w6fw6q 867 1 We -PRON- PRP cord-006870-f5w6fw6q 867 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 867 3 that that IN cord-006870-f5w6fw6q 867 4 the the DT cord-006870-f5w6fw6q 867 5 number number NN cord-006870-f5w6fw6q 867 6 of of IN cord-006870-f5w6fw6q 867 7 traumatic traumatic JJ cord-006870-f5w6fw6q 867 8 microbleeds microbleed NNS cord-006870-f5w6fw6q 867 9 ( ( -LRB- cord-006870-f5w6fw6q 867 10 TMBs TMBs NNP cord-006870-f5w6fw6q 867 11 ) ) -RRB- cord-006870-f5w6fw6q 867 12 detected detect VBN cord-006870-f5w6fw6q 867 13 by by IN cord-006870-f5w6fw6q 867 14 gradient gradient NN cord-006870-f5w6fw6q 867 15 recalled recall VBN cord-006870-f5w6fw6q 867 16 echo echo NN cord-006870-f5w6fw6q 867 17 ( ( -LRB- cord-006870-f5w6fw6q 867 18 GRE GRE NNP cord-006870-f5w6fw6q 867 19 ) ) -RRB- cord-006870-f5w6fw6q 867 20 magnetic magnetic JJ cord-006870-f5w6fw6q 867 21 resonance resonance NN cord-006870-f5w6fw6q 867 22 imaging imaging NN cord-006870-f5w6fw6q 867 23 ( ( -LRB- cord-006870-f5w6fw6q 867 24 MRI MRI NNP cord-006870-f5w6fw6q 867 25 ) ) -RRB- cord-006870-f5w6fw6q 867 26 in in IN cord-006870-f5w6fw6q 867 27 neuroanatomic neuroanatomic JJ cord-006870-f5w6fw6q 867 28 regions region NNS cord-006870-f5w6fw6q 867 29 that that WDT cord-006870-f5w6fw6q 867 30 mediate mediate VBP cord-006870-f5w6fw6q 867 31 memory memory NN cord-006870-f5w6fw6q 867 32 correlates correlate VBZ cord-006870-f5w6fw6q 867 33 more more RBR cord-006870-f5w6fw6q 867 34 strongly strongly RB cord-006870-f5w6fw6q 867 35 with with IN cord-006870-f5w6fw6q 867 36 PTA PTA NNP cord-006870-f5w6fw6q 867 37 duration duration NN cord-006870-f5w6fw6q 867 38 than than IN cord-006870-f5w6fw6q 867 39 does do VBZ cord-006870-f5w6fw6q 867 40 the the DT cord-006870-f5w6fw6q 867 41 number number NN cord-006870-f5w6fw6q 867 42 of of IN cord-006870-f5w6fw6q 867 43 global global JJ cord-006870-f5w6fw6q 867 44 TMBs tmb NNS cord-006870-f5w6fw6q 867 45 . . . cord-006870-f5w6fw6q 868 1 Using use VBG cord-006870-f5w6fw6q 868 2 a a DT cord-006870-f5w6fw6q 868 3 prospective prospective JJ cord-006870-f5w6fw6q 868 4 outcome outcome NN cord-006870-f5w6fw6q 868 5 database database NN cord-006870-f5w6fw6q 868 6 of of IN cord-006870-f5w6fw6q 868 7 patients patient NNS cord-006870-f5w6fw6q 868 8 treated treat VBN cord-006870-f5w6fw6q 868 9 for for IN cord-006870-f5w6fw6q 868 10 mild mild NN cord-006870-f5w6fw6q 868 11 - - HYPH cord-006870-f5w6fw6q 868 12 to to IN cord-006870-f5w6fw6q 868 13 - - HYPH cord-006870-f5w6fw6q 868 14 severe severe JJ cord-006870-f5w6fw6q 868 15 TBI tbi NN cord-006870-f5w6fw6q 868 16 at at IN cord-006870-f5w6fw6q 868 17 an an DT cord-006870-f5w6fw6q 868 18 inpatient inpatient JJ cord-006870-f5w6fw6q 868 19 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 868 20 hospital hospital NN cord-006870-f5w6fw6q 868 21 , , , cord-006870-f5w6fw6q 868 22 we -PRON- PRP cord-006870-f5w6fw6q 868 23 retrospectively retrospectively RB cord-006870-f5w6fw6q 868 24 identified identify VBD cord-006870-f5w6fw6q 868 25 65 65 CD cord-006870-f5w6fw6q 868 26 patients patient NNS cord-006870-f5w6fw6q 868 27 who who WP cord-006870-f5w6fw6q 868 28 underwent undergo VBD cord-006870-f5w6fw6q 868 29 acute acute JJ cord-006870-f5w6fw6q 868 30 MRI MRI NNP cord-006870-f5w6fw6q 868 31 with with IN cord-006870-f5w6fw6q 868 32 GRE GRE NNP cord-006870-f5w6fw6q 868 33 . . . cord-006870-f5w6fw6q 869 1 PTA PTA NNP cord-006870-f5w6fw6q 869 2 duration duration NN cord-006870-f5w6fw6q 869 3 was be VBD cord-006870-f5w6fw6q 869 4 determined determine VBN cord-006870-f5w6fw6q 869 5 by by IN cord-006870-f5w6fw6q 869 6 the the DT cord-006870-f5w6fw6q 869 7 Galveston Galveston NNP cord-006870-f5w6fw6q 869 8 Orientation Orientation NNP cord-006870-f5w6fw6q 869 9 and and CC cord-006870-f5w6fw6q 869 10 Amnesia Amnesia NNP cord-006870-f5w6fw6q 869 11 Test Test NNP cord-006870-f5w6fw6q 869 12 , , , cord-006870-f5w6fw6q 869 13 Orientation Orientation NNP cord-006870-f5w6fw6q 869 14 Log Log NNP cord-006870-f5w6fw6q 869 15 or or CC cord-006870-f5w6fw6q 869 16 chart chart NN cord-006870-f5w6fw6q 869 17 review review NN cord-006870-f5w6fw6q 869 18 . . . cord-006870-f5w6fw6q 870 1 A a DT cord-006870-f5w6fw6q 870 2 rater rater NN cord-006870-f5w6fw6q 870 3 blinded blind VBN cord-006870-f5w6fw6q 870 4 to to IN cord-006870-f5w6fw6q 870 5 PTA PTA NNP cord-006870-f5w6fw6q 870 6 duration duration NN cord-006870-f5w6fw6q 870 7 identified identify VBD cord-006870-f5w6fw6q 870 8 TMBs tmb NNS cord-006870-f5w6fw6q 870 9 on on IN cord-006870-f5w6fw6q 870 10 the the DT cord-006870-f5w6fw6q 870 11 GRE GRE NNP cord-006870-f5w6fw6q 870 12 datasets dataset NNS cord-006870-f5w6fw6q 870 13 globally globally RB cord-006870-f5w6fw6q 870 14 and and CC cord-006870-f5w6fw6q 870 15 in in IN cord-006870-f5w6fw6q 870 16 neuroanatomic neuroanatomic JJ cord-006870-f5w6fw6q 870 17 regions region NNS cord-006870-f5w6fw6q 870 18 that that WDT cord-006870-f5w6fw6q 870 19 mediate mediate VBP cord-006870-f5w6fw6q 870 20 memory memory NN cord-006870-f5w6fw6q 870 21 , , , cord-006870-f5w6fw6q 870 22 including include VBG cord-006870-f5w6fw6q 870 23 the the DT cord-006870-f5w6fw6q 870 24 hippocampus hippocampus NN cord-006870-f5w6fw6q 870 25 , , , cord-006870-f5w6fw6q 870 26 fornix fornix NNP cord-006870-f5w6fw6q 870 27 , , , cord-006870-f5w6fw6q 870 28 corpus corpus NNP cord-006870-f5w6fw6q 870 29 callosum callosum NNP cord-006870-f5w6fw6q 870 30 , , , cord-006870-f5w6fw6q 870 31 thalamus thalamus NNP cord-006870-f5w6fw6q 870 32 , , , cord-006870-f5w6fw6q 870 33 and and CC cord-006870-f5w6fw6q 870 34 the the DT cord-006870-f5w6fw6q 870 35 temporal temporal JJ cord-006870-f5w6fw6q 870 36 lobe lobe NN cord-006870-f5w6fw6q 870 37 . . . cord-006870-f5w6fw6q 871 1 Associations association NNS cord-006870-f5w6fw6q 871 2 between between IN cord-006870-f5w6fw6q 871 3 global global JJ cord-006870-f5w6fw6q 871 4 and and CC cord-006870-f5w6fw6q 871 5 regional regional JJ cord-006870-f5w6fw6q 871 6 TMBs tmb NNS cord-006870-f5w6fw6q 871 7 ( ( -LRB- cord-006870-f5w6fw6q 871 8 in in IN cord-006870-f5w6fw6q 871 9 the the DT cord-006870-f5w6fw6q 871 10 5 5 CD cord-006870-f5w6fw6q 871 11 mentioned mention VBN cord-006870-f5w6fw6q 871 12 locations location NNS cord-006870-f5w6fw6q 871 13 ) ) -RRB- cord-006870-f5w6fw6q 871 14 and and CC cord-006870-f5w6fw6q 871 15 PTA PTA NNP cord-006870-f5w6fw6q 871 16 duration duration NN cord-006870-f5w6fw6q 871 17 were be VBD cord-006870-f5w6fw6q 871 18 tested test VBN cord-006870-f5w6fw6q 871 19 using use VBG cord-006870-f5w6fw6q 871 20 Spearman Spearman NNP cord-006870-f5w6fw6q 871 21 rank rank NN cord-006870-f5w6fw6q 871 22 correlation correlation NN cord-006870-f5w6fw6q 871 23 coefficients coefficient NNS cord-006870-f5w6fw6q 871 24 . . . cord-006870-f5w6fw6q 872 1 The the DT cord-006870-f5w6fw6q 872 2 cohort cohort NN cord-006870-f5w6fw6q 872 3 was be VBD cord-006870-f5w6fw6q 872 4 comprised comprise VBN cord-006870-f5w6fw6q 872 5 of of IN cord-006870-f5w6fw6q 872 6 25 25 CD cord-006870-f5w6fw6q 872 7 % % NN cord-006870-f5w6fw6q 872 8 ( ( -LRB- cord-006870-f5w6fw6q 872 9 _SP cord-006870-f5w6fw6q 872 10 Hippocampus Hippocampus NNP cord-006870-f5w6fw6q 872 11 and and CC cord-006870-f5w6fw6q 872 12 corpus corpus NNP cord-006870-f5w6fw6q 872 13 callosum callosum NNP cord-006870-f5w6fw6q 872 14 TMBs TMBs NNP cord-006870-f5w6fw6q 872 15 are be VBP cord-006870-f5w6fw6q 872 16 associated associate VBN cord-006870-f5w6fw6q 872 17 with with IN cord-006870-f5w6fw6q 872 18 PTA PTA NNP cord-006870-f5w6fw6q 872 19 duration duration NN cord-006870-f5w6fw6q 872 20 , , , cord-006870-f5w6fw6q 872 21 and and CC cord-006870-f5w6fw6q 872 22 thus thus RB cord-006870-f5w6fw6q 872 23 may may MD cord-006870-f5w6fw6q 872 24 have have VB cord-006870-f5w6fw6q 872 25 greater great JJR cord-006870-f5w6fw6q 872 26 utility utility NN cord-006870-f5w6fw6q 872 27 for for IN cord-006870-f5w6fw6q 872 28 predicting predict VBG cord-006870-f5w6fw6q 872 29 functional functional JJ cord-006870-f5w6fw6q 872 30 outcomes outcome NNS cord-006870-f5w6fw6q 872 31 than than IN cord-006870-f5w6fw6q 872 32 global global JJ cord-006870-f5w6fw6q 872 33 TMB tmb NN cord-006870-f5w6fw6q 872 34 number number NN cord-006870-f5w6fw6q 872 35 . . . cord-006870-f5w6fw6q 873 1 Validation validation NN cord-006870-f5w6fw6q 873 2 of of IN cord-006870-f5w6fw6q 873 3 these these DT cord-006870-f5w6fw6q 873 4 findings finding NNS cord-006870-f5w6fw6q 873 5 in in IN cord-006870-f5w6fw6q 873 6 larger large JJR cord-006870-f5w6fw6q 873 7 prospective prospective JJ cord-006870-f5w6fw6q 873 8 studies study NNS cord-006870-f5w6fw6q 873 9 is be VBZ cord-006870-f5w6fw6q 873 10 indicated indicate VBN cord-006870-f5w6fw6q 873 11 . . . cord-006870-f5w6fw6q 874 1 Using use VBG cord-006870-f5w6fw6q 874 2 a a DT cord-006870-f5w6fw6q 874 3 large large JJ cord-006870-f5w6fw6q 874 4 two two CD cord-006870-f5w6fw6q 874 5 - - HYPH cord-006870-f5w6fw6q 874 6 center center NN cord-006870-f5w6fw6q 874 7 cohort cohort NN cord-006870-f5w6fw6q 874 8 of of IN cord-006870-f5w6fw6q 874 9 413 413 CD cord-006870-f5w6fw6q 874 10 penetrating penetrate VBG cord-006870-f5w6fw6q 874 11 traumatic traumatic JJ cord-006870-f5w6fw6q 874 12 brain brain NN cord-006870-f5w6fw6q 874 13 injury injury NN cord-006870-f5w6fw6q 874 14 ( ( -LRB- cord-006870-f5w6fw6q 874 15 pTBI ptbi NN cord-006870-f5w6fw6q 874 16 ) ) -RRB- cord-006870-f5w6fw6q 874 17 patients patient NNS cord-006870-f5w6fw6q 874 18 , , , cord-006870-f5w6fw6q 874 19 we -PRON- PRP cord-006870-f5w6fw6q 874 20 previously previously RB cord-006870-f5w6fw6q 874 21 developed develop VBD cord-006870-f5w6fw6q 874 22 the the DT cord-006870-f5w6fw6q 874 23 Survival Survival NNP cord-006870-f5w6fw6q 874 24 after after IN cord-006870-f5w6fw6q 875 1 Acute acute JJ cord-006870-f5w6fw6q 875 2 Civilian Civilian NNP cord-006870-f5w6fw6q 875 3 Penetrating Penetrating NNP cord-006870-f5w6fw6q 875 4 Brain Brain NNP cord-006870-f5w6fw6q 875 5 Injuries Injuries NNPS cord-006870-f5w6fw6q 875 6 ( ( -LRB- cord-006870-f5w6fw6q 875 7 SPIN spin NN cord-006870-f5w6fw6q 875 8 ) ) -RRB- cord-006870-f5w6fw6q 875 9 Score score NN cord-006870-f5w6fw6q 875 10 , , , cord-006870-f5w6fw6q 875 11 a a DT cord-006870-f5w6fw6q 875 12 logistic logistic JJ cord-006870-f5w6fw6q 875 13 regressionbased regressionbase VBN cord-006870-f5w6fw6q 875 14 parsimonious parsimonious JJ cord-006870-f5w6fw6q 875 15 risk risk NN cord-006870-f5w6fw6q 875 16 stratification stratification NN cord-006870-f5w6fw6q 875 17 scale scale NN cord-006870-f5w6fw6q 875 18 for for IN cord-006870-f5w6fw6q 875 19 estimating estimate VBG cord-006870-f5w6fw6q 875 20 survival survival NN cord-006870-f5w6fw6q 875 21 after after IN cord-006870-f5w6fw6q 875 22 civilian civilian JJ cord-006870-f5w6fw6q 875 23 pTBI ptbi NN cord-006870-f5w6fw6q 875 24 . . . cord-006870-f5w6fw6q 876 1 The the DT cord-006870-f5w6fw6q 876 2 objective objective NN cord-006870-f5w6fw6q 876 3 of of IN cord-006870-f5w6fw6q 876 4 the the DT cord-006870-f5w6fw6q 876 5 present present JJ cord-006870-f5w6fw6q 876 6 study study NN cord-006870-f5w6fw6q 876 7 was be VBD cord-006870-f5w6fw6q 876 8 to to TO cord-006870-f5w6fw6q 876 9 externally externally RB cord-006870-f5w6fw6q 876 10 validate validate VB cord-006870-f5w6fw6q 876 11 the the DT cord-006870-f5w6fw6q 876 12 SPIN spin NN cord-006870-f5w6fw6q 876 13 - - HYPH cord-006870-f5w6fw6q 876 14 Score score NN cord-006870-f5w6fw6q 876 15 . . . cord-006870-f5w6fw6q 877 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 877 2 multicenter multicenter JJ cord-006870-f5w6fw6q 877 3 validation validation NN cord-006870-f5w6fw6q 877 4 cohort cohort NN cord-006870-f5w6fw6q 877 5 comprised comprise VBD cord-006870-f5w6fw6q 877 6 362 362 CD cord-006870-f5w6fw6q 877 7 pTBI ptbi NN cord-006870-f5w6fw6q 877 8 patients patient NNS cord-006870-f5w6fw6q 877 9 retrospectively retrospectively RB cord-006870-f5w6fw6q 877 10 identified identify VBN cord-006870-f5w6fw6q 877 11 from from IN cord-006870-f5w6fw6q 877 12 three three CD cord-006870-f5w6fw6q 877 13 U.S. U.S. NNP cord-006870-f5w6fw6q 877 14 Level-1 Level-1 NNP cord-006870-f5w6fw6q 877 15 trauma trauma NN cord-006870-f5w6fw6q 877 16 center center NN cord-006870-f5w6fw6q 877 17 registries registry NNS cord-006870-f5w6fw6q 877 18 . . . cord-006870-f5w6fw6q 878 1 The the DT cord-006870-f5w6fw6q 878 2 SPIN spin NN cord-006870-f5w6fw6q 878 3 score score NN cord-006870-f5w6fw6q 878 4 variables variable NNS cord-006870-f5w6fw6q 878 5 ( ( -LRB- cord-006870-f5w6fw6q 878 6 motor motor NN cord-006870-f5w6fw6q 878 7 GCS GCS NNP cord-006870-f5w6fw6q 878 8 [ [ -LRB- cord-006870-f5w6fw6q 878 9 mGCS mGCS NNP cord-006870-f5w6fw6q 878 10 ] ] -RRB- cord-006870-f5w6fw6q 878 11 , , , cord-006870-f5w6fw6q 878 12 sex sex NN cord-006870-f5w6fw6q 878 13 , , , cord-006870-f5w6fw6q 878 14 pupillary pupillary JJ cord-006870-f5w6fw6q 878 15 reactivity reactivity NN cord-006870-f5w6fw6q 878 16 , , , cord-006870-f5w6fw6q 878 17 self self NN cord-006870-f5w6fw6q 878 18 - - HYPH cord-006870-f5w6fw6q 878 19 inflicted inflict VBN cord-006870-f5w6fw6q 878 20 pTBI ptbi NN cord-006870-f5w6fw6q 878 21 , , , cord-006870-f5w6fw6q 878 22 transfer transfer NN cord-006870-f5w6fw6q 878 23 status status NN cord-006870-f5w6fw6q 878 24 , , , cord-006870-f5w6fw6q 878 25 Injury injury NN cord-006870-f5w6fw6q 878 26 Severity severity NN cord-006870-f5w6fw6q 878 27 Score score NN cord-006870-f5w6fw6q 878 28 [ [ -LRB- cord-006870-f5w6fw6q 878 29 ISS ISS NNP cord-006870-f5w6fw6q 878 30 ] ] -RRB- cord-006870-f5w6fw6q 878 31 and and CC cord-006870-f5w6fw6q 878 32 INR INR NNP cord-006870-f5w6fw6q 878 33 ) ) -RRB- cord-006870-f5w6fw6q 878 34 were be VBD cord-006870-f5w6fw6q 878 35 collected collect VBN cord-006870-f5w6fw6q 878 36 from from IN cord-006870-f5w6fw6q 878 37 the the DT cord-006870-f5w6fw6q 878 38 trauma trauma NN cord-006870-f5w6fw6q 878 39 registries registry NNS cord-006870-f5w6fw6q 878 40 supplemented supplement VBN cord-006870-f5w6fw6q 878 41 by by IN cord-006870-f5w6fw6q 878 42 chart chart NN cord-006870-f5w6fw6q 878 43 review review NN cord-006870-f5w6fw6q 878 44 . . . cord-006870-f5w6fw6q 879 1 Using use VBG cord-006870-f5w6fw6q 879 2 the the DT cord-006870-f5w6fw6q 879 3 SPIN spin NN cord-006870-f5w6fw6q 879 4 - - HYPH cord-006870-f5w6fw6q 879 5 score score NN cord-006870-f5w6fw6q 879 6 multivariable multivariable JJ cord-006870-f5w6fw6q 879 7 logistic logistic JJ cord-006870-f5w6fw6q 879 8 regression regression NN cord-006870-f5w6fw6q 879 9 model model NN cord-006870-f5w6fw6q 879 10 from from IN cord-006870-f5w6fw6q 879 11 the the DT cord-006870-f5w6fw6q 879 12 original original JJ cord-006870-f5w6fw6q 879 13 study study NN cord-006870-f5w6fw6q 879 14 , , , cord-006870-f5w6fw6q 879 15 receiver receiver NN cord-006870-f5w6fw6q 879 16 - - HYPH cord-006870-f5w6fw6q 879 17 operating operate VBG cord-006870-f5w6fw6q 879 18 - - HYPH cord-006870-f5w6fw6q 879 19 characteristic characteristic JJ cord-006870-f5w6fw6q 879 20 area area NN cord-006870-f5w6fw6q 879 21 - - HYPH cord-006870-f5w6fw6q 879 22 under under IN cord-006870-f5w6fw6q 879 23 - - HYPH cord-006870-f5w6fw6q 879 24 the the DT cord-006870-f5w6fw6q 879 25 - - HYPH cord-006870-f5w6fw6q 879 26 curve curve NN cord-006870-f5w6fw6q 879 27 ( ( -LRB- cord-006870-f5w6fw6q 879 28 ROC ROC NNP cord-006870-f5w6fw6q 879 29 - - HYPH cord-006870-f5w6fw6q 879 30 AUC AUC NNP cord-006870-f5w6fw6q 879 31 ) ) -RRB- cord-006870-f5w6fw6q 879 32 analysis analysis NN cord-006870-f5w6fw6q 879 33 and and CC cord-006870-f5w6fw6q 879 34 Hosmer Hosmer NNP cord-006870-f5w6fw6q 879 35 - - HYPH cord-006870-f5w6fw6q 879 36 Lemeshow Lemeshow NNP cord-006870-f5w6fw6q 880 1 Goodness goodness NN cord-006870-f5w6fw6q 880 2 - - HYPH cord-006870-f5w6fw6q 880 3 of of IN cord-006870-f5w6fw6q 880 4 - - HYPH cord-006870-f5w6fw6q 880 5 fit fit JJ cord-006870-f5w6fw6q 880 6 testing testing NN cord-006870-f5w6fw6q 880 7 was be VBD cord-006870-f5w6fw6q 880 8 performed perform VBN cord-006870-f5w6fw6q 880 9 . . . cord-006870-f5w6fw6q 881 1 The the DT cord-006870-f5w6fw6q 881 2 mean mean JJ cord-006870-f5w6fw6q 881 3 age age NN cord-006870-f5w6fw6q 881 4 was be VBD cord-006870-f5w6fw6q 881 5 32±15 32±15 NNP cord-006870-f5w6fw6q 881 6 years year NNS cord-006870-f5w6fw6q 881 7 , , , cord-006870-f5w6fw6q 881 8 and and CC cord-006870-f5w6fw6q 881 9 patients patient NNS cord-006870-f5w6fw6q 881 10 were be VBD cord-006870-f5w6fw6q 881 11 predominantly predominantly RB cord-006870-f5w6fw6q 881 12 male male JJ cord-006870-f5w6fw6q 881 13 ( ( -LRB- cord-006870-f5w6fw6q 881 14 85 85 CD cord-006870-f5w6fw6q 881 15 % % NN cord-006870-f5w6fw6q 881 16 ) ) -RRB- cord-006870-f5w6fw6q 881 17 , , , cord-006870-f5w6fw6q 881 18 with with IN cord-006870-f5w6fw6q 881 19 41 41 CD cord-006870-f5w6fw6q 881 20 % % NN cord-006870-f5w6fw6q 881 21 white white JJ cord-006870-f5w6fw6q 881 22 and and CC cord-006870-f5w6fw6q 881 23 28 28 CD cord-006870-f5w6fw6q 881 24 % % NN cord-006870-f5w6fw6q 881 25 black black NN cord-006870-f5w6fw6q 881 26 . . . cord-006870-f5w6fw6q 882 1 In in IN cord-006870-f5w6fw6q 882 2 - - HYPH cord-006870-f5w6fw6q 882 3 hospital hospital NN cord-006870-f5w6fw6q 882 4 mortality mortality NN cord-006870-f5w6fw6q 882 5 was be VBD cord-006870-f5w6fw6q 882 6 52 52 CD cord-006870-f5w6fw6q 882 7 % % NN cord-006870-f5w6fw6q 882 8 , , , cord-006870-f5w6fw6q 882 9 and and CC cord-006870-f5w6fw6q 882 10 6-month 6-month CD cord-006870-f5w6fw6q 882 11 mortality mortality NN cord-006870-f5w6fw6q 882 12 of of IN cord-006870-f5w6fw6q 882 13 discharge discharge NN cord-006870-f5w6fw6q 882 14 survivors survivor NNS cord-006870-f5w6fw6q 882 15 was be VBD cord-006870-f5w6fw6q 882 16 3 3 CD cord-006870-f5w6fw6q 882 17 . . . cord-006870-f5w6fw6q 882 18 _SP cord-006870-f5w6fw6q 883 1 In in IN cord-006870-f5w6fw6q 883 2 this this DT cord-006870-f5w6fw6q 883 3 multicenter multicenter JJ cord-006870-f5w6fw6q 883 4 external external JJ cord-006870-f5w6fw6q 883 5 validation validation NN cord-006870-f5w6fw6q 883 6 study study NN cord-006870-f5w6fw6q 883 7 , , , cord-006870-f5w6fw6q 883 8 the the DT cord-006870-f5w6fw6q 883 9 full full JJ cord-006870-f5w6fw6q 883 10 SPIN spin NN cord-006870-f5w6fw6q 883 11 - - HYPH cord-006870-f5w6fw6q 883 12 model model NN cord-006870-f5w6fw6q 883 13 predicts predict VBZ cord-006870-f5w6fw6q 883 14 in in IN cord-006870-f5w6fw6q 883 15 - - HYPH cord-006870-f5w6fw6q 883 16 hospital hospital NN cord-006870-f5w6fw6q 883 17 survival survival NN cord-006870-f5w6fw6q 883 18 after after IN cord-006870-f5w6fw6q 883 19 pTBI ptbi NN cord-006870-f5w6fw6q 883 20 with with IN cord-006870-f5w6fw6q 883 21 excellent excellent JJ cord-006870-f5w6fw6q 883 22 discrimination discrimination NN cord-006870-f5w6fw6q 883 23 and and CC cord-006870-f5w6fw6q 883 24 calibration calibration NN cord-006870-f5w6fw6q 883 25 . . . cord-006870-f5w6fw6q 884 1 After after IN cord-006870-f5w6fw6q 884 2 removing remove VBG cord-006870-f5w6fw6q 884 3 INR INR NNP cord-006870-f5w6fw6q 884 4 from from IN cord-006870-f5w6fw6q 884 5 the the DT cord-006870-f5w6fw6q 884 6 model model NN cord-006870-f5w6fw6q 884 7 , , , cord-006870-f5w6fw6q 884 8 discrimination discrimination NN cord-006870-f5w6fw6q 884 9 remained remain VBD cord-006870-f5w6fw6q 884 10 excellent excellent JJ cord-006870-f5w6fw6q 884 11 , , , cord-006870-f5w6fw6q 884 12 but but CC cord-006870-f5w6fw6q 884 13 model model NN cord-006870-f5w6fw6q 884 14 calibration calibration NN cord-006870-f5w6fw6q 884 15 diminished diminish VBD cord-006870-f5w6fw6q 884 16 . . . cord-006870-f5w6fw6q 885 1 The the DT cord-006870-f5w6fw6q 885 2 full full JJ cord-006870-f5w6fw6q 885 3 SPIN spin NN cord-006870-f5w6fw6q 885 4 - - HYPH cord-006870-f5w6fw6q 885 5 score score NN cord-006870-f5w6fw6q 885 6 may may MD cord-006870-f5w6fw6q 885 7 provide provide VB cord-006870-f5w6fw6q 885 8 important important JJ cord-006870-f5w6fw6q 885 9 information information NN cord-006870-f5w6fw6q 885 10 to to TO cord-006870-f5w6fw6q 885 11 guide guide VB cord-006870-f5w6fw6q 885 12 families family NNS cord-006870-f5w6fw6q 885 13 and and CC cord-006870-f5w6fw6q 885 14 physicians physician NNS cord-006870-f5w6fw6q 885 15 after after IN cord-006870-f5w6fw6q 885 16 civilian civilian JJ cord-006870-f5w6fw6q 885 17 pTBI ptbi NN cord-006870-f5w6fw6q 885 18 . . . cord-006870-f5w6fw6q 886 1 Limited limited JJ cord-006870-f5w6fw6q 886 2 data datum NNS cord-006870-f5w6fw6q 886 3 has have VBZ cord-006870-f5w6fw6q 886 4 described describe VBN cord-006870-f5w6fw6q 886 5 alterations alteration NNS cord-006870-f5w6fw6q 886 6 in in IN cord-006870-f5w6fw6q 886 7 vancomycin vancomycin NN cord-006870-f5w6fw6q 886 8 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 886 9 ( ( -LRB- cord-006870-f5w6fw6q 886 10 PK PK NNP cord-006870-f5w6fw6q 886 11 ) ) -RRB- cord-006870-f5w6fw6q 886 12 parameters parameter NNS cord-006870-f5w6fw6q 886 13 in in IN cord-006870-f5w6fw6q 886 14 traumatic traumatic JJ cord-006870-f5w6fw6q 886 15 brain brain NN cord-006870-f5w6fw6q 886 16 injury injury NN cord-006870-f5w6fw6q 886 17 ( ( -LRB- cord-006870-f5w6fw6q 886 18 TBI TBI NNP cord-006870-f5w6fw6q 886 19 ) ) -RRB- cord-006870-f5w6fw6q 886 20 patients patient NNS cord-006870-f5w6fw6q 886 21 that that WDT cord-006870-f5w6fw6q 886 22 have have VBP cord-006870-f5w6fw6q 886 23 resulted result VBN cord-006870-f5w6fw6q 886 24 in in IN cord-006870-f5w6fw6q 886 25 sub sub JJ cord-006870-f5w6fw6q 886 26 - - JJ cord-006870-f5w6fw6q 886 27 therapeutic therapeutic JJ cord-006870-f5w6fw6q 886 28 concentrations concentration NNS cord-006870-f5w6fw6q 886 29 . . . cord-006870-f5w6fw6q 887 1 The the DT cord-006870-f5w6fw6q 887 2 primary primary JJ cord-006870-f5w6fw6q 887 3 objective objective NN cord-006870-f5w6fw6q 887 4 of of IN cord-006870-f5w6fw6q 887 5 this this DT cord-006870-f5w6fw6q 887 6 study study NN cord-006870-f5w6fw6q 887 7 is be VBZ cord-006870-f5w6fw6q 887 8 to to TO cord-006870-f5w6fw6q 887 9 evaluate evaluate VB cord-006870-f5w6fw6q 887 10 the the DT cord-006870-f5w6fw6q 887 11 PK PK NNP cord-006870-f5w6fw6q 887 12 parameters parameter NNS cord-006870-f5w6fw6q 887 13 of of IN cord-006870-f5w6fw6q 887 14 vancomycin vancomycin NN cord-006870-f5w6fw6q 887 15 in in IN cord-006870-f5w6fw6q 887 16 TBI TBI NNP cord-006870-f5w6fw6q 887 17 patients patient NNS cord-006870-f5w6fw6q 887 18 to to TO cord-006870-f5w6fw6q 887 19 determine determine VB cord-006870-f5w6fw6q 887 20 if if IN cord-006870-f5w6fw6q 887 21 using use VBG cord-006870-f5w6fw6q 887 22 the the DT cord-006870-f5w6fw6q 887 23 common common JJ cord-006870-f5w6fw6q 887 24 clinical clinical JJ cord-006870-f5w6fw6q 887 25 practice practice NN cord-006870-f5w6fw6q 887 26 of of IN cord-006870-f5w6fw6q 887 27 capping cap VBG cord-006870-f5w6fw6q 887 28 creatinine creatinine NN cord-006870-f5w6fw6q 887 29 clearance clearance NN cord-006870-f5w6fw6q 887 30 ( ( -LRB- cord-006870-f5w6fw6q 887 31 CrCl CrCl NNP cord-006870-f5w6fw6q 887 32 ) ) -RRB- cord-006870-f5w6fw6q 887 33 to to IN cord-006870-f5w6fw6q 887 34 120 120 CD cord-006870-f5w6fw6q 887 35 mL ml NN cord-006870-f5w6fw6q 887 36 / / SYM cord-006870-f5w6fw6q 887 37 min min NN cord-006870-f5w6fw6q 887 38 in in IN cord-006870-f5w6fw6q 887 39 determining determine VBG cord-006870-f5w6fw6q 887 40 dosing dosing NN cord-006870-f5w6fw6q 887 41 impacts impact NNS cord-006870-f5w6fw6q 887 42 achievement achievement NN cord-006870-f5w6fw6q 887 43 of of IN cord-006870-f5w6fw6q 887 44 therapeutic therapeutic JJ cord-006870-f5w6fw6q 887 45 concentrations concentration NNS cord-006870-f5w6fw6q 887 46 . . . cord-006870-f5w6fw6q 888 1 This this DT cord-006870-f5w6fw6q 888 2 was be VBD cord-006870-f5w6fw6q 888 3 a a DT cord-006870-f5w6fw6q 888 4 single single JJ cord-006870-f5w6fw6q 888 5 - - HYPH cord-006870-f5w6fw6q 888 6 center center NN cord-006870-f5w6fw6q 888 7 , , , cord-006870-f5w6fw6q 888 8 retrospective retrospective JJ cord-006870-f5w6fw6q 888 9 study study NN cord-006870-f5w6fw6q 888 10 of of IN cord-006870-f5w6fw6q 888 11 patients patient NNS cord-006870-f5w6fw6q 888 12 at at IN cord-006870-f5w6fw6q 888 13 least least JJS cord-006870-f5w6fw6q 888 14 18 18 CD cord-006870-f5w6fw6q 888 15 years year NNS cord-006870-f5w6fw6q 888 16 of of IN cord-006870-f5w6fw6q 888 17 age age NN cord-006870-f5w6fw6q 888 18 with with IN cord-006870-f5w6fw6q 888 19 TBI TBI NNP cord-006870-f5w6fw6q 888 20 who who WP cord-006870-f5w6fw6q 888 21 received receive VBD cord-006870-f5w6fw6q 888 22 vancomycin vancomycin NN cord-006870-f5w6fw6q 888 23 and and CC cord-006870-f5w6fw6q 888 24 one one CD cord-006870-f5w6fw6q 888 25 reported report VBD cord-006870-f5w6fw6q 888 26 steady steady JJ cord-006870-f5w6fw6q 888 27 - - HYPH cord-006870-f5w6fw6q 888 28 state state NN cord-006870-f5w6fw6q 888 29 vancomycin vancomycin NN cord-006870-f5w6fw6q 888 30 serum serum NN cord-006870-f5w6fw6q 888 31 level level NN cord-006870-f5w6fw6q 888 32 from from IN cord-006870-f5w6fw6q 888 33 April April NNP cord-006870-f5w6fw6q 888 34 2014 2014 CD cord-006870-f5w6fw6q 888 35 to to IN cord-006870-f5w6fw6q 888 36 December December NNP cord-006870-f5w6fw6q 888 37 2015 2015 CD cord-006870-f5w6fw6q 888 38 . . . cord-006870-f5w6fw6q 889 1 Predicted predict VBN cord-006870-f5w6fw6q 889 2 PK PK NNP cord-006870-f5w6fw6q 889 3 parameters parameter NNS cord-006870-f5w6fw6q 889 4 based base VBN cord-006870-f5w6fw6q 889 5 on on IN cord-006870-f5w6fw6q 889 6 population population NN cord-006870-f5w6fw6q 889 7 data datum NNS cord-006870-f5w6fw6q 889 8 using use VBG cord-006870-f5w6fw6q 889 9 actual actual JJ cord-006870-f5w6fw6q 889 10 and and CC cord-006870-f5w6fw6q 889 11 capped capped JJ cord-006870-f5w6fw6q 889 12 creatinine creatinine NN cord-006870-f5w6fw6q 889 13 clearance clearance NN cord-006870-f5w6fw6q 889 14 ( ( -LRB- cord-006870-f5w6fw6q 889 15 CrCl CrCl NNP cord-006870-f5w6fw6q 889 16 ) ) -RRB- cord-006870-f5w6fw6q 889 17 at at IN cord-006870-f5w6fw6q 889 18 120mL 120mL NNP cord-006870-f5w6fw6q 889 19 / / SYM cord-006870-f5w6fw6q 889 20 min min NNP cord-006870-f5w6fw6q 889 21 were be VBD cord-006870-f5w6fw6q 889 22 compared compare VBN cord-006870-f5w6fw6q 889 23 with with IN cord-006870-f5w6fw6q 889 24 calculated calculate VBN cord-006870-f5w6fw6q 889 25 PK PK NNP cord-006870-f5w6fw6q 889 26 parameters parameter NNS cord-006870-f5w6fw6q 889 27 based base VBN cord-006870-f5w6fw6q 889 28 on on IN cord-006870-f5w6fw6q 889 29 serum serum NN cord-006870-f5w6fw6q 889 30 trough trough NN cord-006870-f5w6fw6q 889 31 concentrations concentration NNS cord-006870-f5w6fw6q 889 32 at at IN cord-006870-f5w6fw6q 889 33 steady steady JJ cord-006870-f5w6fw6q 889 34 state state NN cord-006870-f5w6fw6q 889 35 . . . cord-006870-f5w6fw6q 890 1 The the DT cord-006870-f5w6fw6q 890 2 difference difference NN cord-006870-f5w6fw6q 890 3 was be VBD cord-006870-f5w6fw6q 890 4 assessed assess VBN cord-006870-f5w6fw6q 890 5 using use VBG cord-006870-f5w6fw6q 890 6 a a DT cord-006870-f5w6fw6q 890 7 two two CD cord-006870-f5w6fw6q 890 8 - - HYPH cord-006870-f5w6fw6q 890 9 sample sample NN cord-006870-f5w6fw6q 890 10 Wilcoxon Wilcoxon NNP cord-006870-f5w6fw6q 890 11 rank rank NN cord-006870-f5w6fw6q 890 12 - - HYPH cord-006870-f5w6fw6q 890 13 sum sum NN cord-006870-f5w6fw6q 890 14 test test NN cord-006870-f5w6fw6q 890 15 where where WRB cord-006870-f5w6fw6q 890 16 p p NN cord-006870-f5w6fw6q 890 17 < < XX cord-006870-f5w6fw6q 890 18 0.05 0.05 CD cord-006870-f5w6fw6q 890 19 was be VBD cord-006870-f5w6fw6q 890 20 considered consider VBN cord-006870-f5w6fw6q 890 21 statistically statistically RB cord-006870-f5w6fw6q 890 22 significant significant JJ cord-006870-f5w6fw6q 890 23 . . . cord-006870-f5w6fw6q 891 1 When when WRB cord-006870-f5w6fw6q 891 2 using use VBG cord-006870-f5w6fw6q 891 3 actual actual JJ cord-006870-f5w6fw6q 891 4 CrCl crcl NN cord-006870-f5w6fw6q 891 5 [ [ -LRB- cord-006870-f5w6fw6q 891 6 median median NN cord-006870-f5w6fw6q 891 7 167 167 CD cord-006870-f5w6fw6q 891 8 mL ml NN cord-006870-f5w6fw6q 891 9 / / SYM cord-006870-f5w6fw6q 891 10 min min NN cord-006870-f5w6fw6q 891 11 _SP cord-006870-f5w6fw6q 891 12 Patients Patients NNP cord-006870-f5w6fw6q 891 13 with with IN cord-006870-f5w6fw6q 891 14 TBI TBI NNP cord-006870-f5w6fw6q 891 15 experienced experience VBD cord-006870-f5w6fw6q 891 16 CrCl CrCl NNP cord-006870-f5w6fw6q 891 17 that that WDT cord-006870-f5w6fw6q 891 18 were be VBD cord-006870-f5w6fw6q 891 19 greater great JJR cord-006870-f5w6fw6q 891 20 than than IN cord-006870-f5w6fw6q 891 21 predicted predict VBN cord-006870-f5w6fw6q 891 22 . . . cord-006870-f5w6fw6q 892 1 Based base VBN cord-006870-f5w6fw6q 892 2 on on IN cord-006870-f5w6fw6q 892 3 the the DT cord-006870-f5w6fw6q 892 4 results result NNS cord-006870-f5w6fw6q 892 5 of of IN cord-006870-f5w6fw6q 892 6 this this DT cord-006870-f5w6fw6q 892 7 study study NN cord-006870-f5w6fw6q 892 8 , , , cord-006870-f5w6fw6q 892 9 actual actual JJ cord-006870-f5w6fw6q 892 10 CrCl crcl NN cord-006870-f5w6fw6q 892 11 is be VBZ cord-006870-f5w6fw6q 892 12 more more RBR cord-006870-f5w6fw6q 892 13 accurate accurate JJ cord-006870-f5w6fw6q 892 14 at at IN cord-006870-f5w6fw6q 892 15 predicting predict VBG cord-006870-f5w6fw6q 892 16 vancomycin vancomycin FW cord-006870-f5w6fw6q 892 17 PK PK NNP cord-006870-f5w6fw6q 892 18 than than IN cord-006870-f5w6fw6q 892 19 the the DT cord-006870-f5w6fw6q 892 20 common common JJ cord-006870-f5w6fw6q 892 21 practice practice NN cord-006870-f5w6fw6q 892 22 of of IN cord-006870-f5w6fw6q 892 23 capping cap VBG cord-006870-f5w6fw6q 892 24 CrCl CrCl NNP cord-006870-f5w6fw6q 892 25 at at IN cord-006870-f5w6fw6q 892 26 120mL 120mL NNP cord-006870-f5w6fw6q 892 27 / / SYM cord-006870-f5w6fw6q 892 28 min min NN cord-006870-f5w6fw6q 892 29 . . . cord-006870-f5w6fw6q 893 1 Therefore therefore RB cord-006870-f5w6fw6q 893 2 , , , cord-006870-f5w6fw6q 893 3 actual actual JJ cord-006870-f5w6fw6q 893 4 CrCl crcl NN cord-006870-f5w6fw6q 893 5 should should MD cord-006870-f5w6fw6q 893 6 be be VB cord-006870-f5w6fw6q 893 7 used use VBN cord-006870-f5w6fw6q 893 8 when when WRB cord-006870-f5w6fw6q 893 9 determining determine VBG cord-006870-f5w6fw6q 893 10 vancomycin vancomycin FW cord-006870-f5w6fw6q 893 11 dosing dose VBG cord-006870-f5w6fw6q 893 12 regimens regimen NNS cord-006870-f5w6fw6q 893 13 in in IN cord-006870-f5w6fw6q 893 14 patients patient NNS cord-006870-f5w6fw6q 893 15 with with IN cord-006870-f5w6fw6q 893 16 TBI TBI NNP cord-006870-f5w6fw6q 893 17 to to TO cord-006870-f5w6fw6q 893 18 achieve achieve VB cord-006870-f5w6fw6q 893 19 desired desire VBN cord-006870-f5w6fw6q 893 20 therapeutic therapeutic JJ cord-006870-f5w6fw6q 893 21 concentrations concentration NNS cord-006870-f5w6fw6q 893 22 . . . cord-006870-f5w6fw6q 894 1 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 894 2 care care NN cord-006870-f5w6fw6q 894 3 is be VBZ cord-006870-f5w6fw6q 894 4 traditionally traditionally RB cord-006870-f5w6fw6q 894 5 provided provide VBN cord-006870-f5w6fw6q 894 6 within within IN cord-006870-f5w6fw6q 894 7 institutions institution NNS cord-006870-f5w6fw6q 894 8 in in IN cord-006870-f5w6fw6q 894 9 urban urban JJ cord-006870-f5w6fw6q 894 10 centers center NNS cord-006870-f5w6fw6q 894 11 while while IN cord-006870-f5w6fw6q 894 12 access access NN cord-006870-f5w6fw6q 894 13 in in IN cord-006870-f5w6fw6q 894 14 rural rural JJ cord-006870-f5w6fw6q 894 15 communities community NNS cord-006870-f5w6fw6q 894 16 has have VBZ cord-006870-f5w6fw6q 894 17 been be VBN cord-006870-f5w6fw6q 894 18 limited limit VBN cord-006870-f5w6fw6q 894 19 . . . cord-006870-f5w6fw6q 895 1 Transport transport NN cord-006870-f5w6fw6q 895 2 to to IN cord-006870-f5w6fw6q 895 3 urban urban JJ cord-006870-f5w6fw6q 895 4 centers center NNS cord-006870-f5w6fw6q 895 5 is be VBZ cord-006870-f5w6fw6q 895 6 not not RB cord-006870-f5w6fw6q 895 7 always always RB cord-006870-f5w6fw6q 895 8 favorable favorable JJ cord-006870-f5w6fw6q 895 9 for for IN cord-006870-f5w6fw6q 895 10 a a DT cord-006870-f5w6fw6q 895 11 variety variety NN cord-006870-f5w6fw6q 895 12 of of IN cord-006870-f5w6fw6q 895 13 reasons reason NNS cord-006870-f5w6fw6q 895 14 including include VBG cord-006870-f5w6fw6q 895 15 critical critical JJ cord-006870-f5w6fw6q 895 16 patient patient JJ cord-006870-f5w6fw6q 895 17 condition condition NN cord-006870-f5w6fw6q 895 18 , , , cord-006870-f5w6fw6q 895 19 family family NN cord-006870-f5w6fw6q 895 20 wishes wish VBZ cord-006870-f5w6fw6q 895 21 , , , cord-006870-f5w6fw6q 895 22 weather weather NN cord-006870-f5w6fw6q 895 23 , , , cord-006870-f5w6fw6q 895 24 and and CC cord-006870-f5w6fw6q 895 25 geography geography NN cord-006870-f5w6fw6q 895 26 . . . cord-006870-f5w6fw6q 896 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 896 2 hypothesis hypothesis NN cord-006870-f5w6fw6q 896 3 is be VBZ cord-006870-f5w6fw6q 896 4 that that IN cord-006870-f5w6fw6q 896 5 tele tele NNP cord-006870-f5w6fw6q 896 6 - - HYPH cord-006870-f5w6fw6q 896 7 neurocritical neurocritical NNP cord-006870-f5w6fw6q 896 8 ( ( -LRB- cord-006870-f5w6fw6q 896 9 Tele Tele NNP cord-006870-f5w6fw6q 896 10 - - HYPH cord-006870-f5w6fw6q 896 11 NCC NCC NNP cord-006870-f5w6fw6q 896 12 ) ) -RRB- cord-006870-f5w6fw6q 896 13 can can MD cord-006870-f5w6fw6q 896 14 extend extend VB cord-006870-f5w6fw6q 896 15 access access NN cord-006870-f5w6fw6q 896 16 to to IN cord-006870-f5w6fw6q 896 17 this this DT cord-006870-f5w6fw6q 896 18 service service NN cord-006870-f5w6fw6q 896 19 with with IN cord-006870-f5w6fw6q 896 20 meaningful meaningful JJ cord-006870-f5w6fw6q 896 21 impact impact NN cord-006870-f5w6fw6q 896 22 on on IN cord-006870-f5w6fw6q 896 23 ICU ICU NNP cord-006870-f5w6fw6q 896 24 outcomes outcome NNS cord-006870-f5w6fw6q 896 25 . . . cord-006870-f5w6fw6q 897 1 A a DT cord-006870-f5w6fw6q 897 2 Tele Tele NNP cord-006870-f5w6fw6q 897 3 - - HYPH cord-006870-f5w6fw6q 897 4 NCC NCC NNP cord-006870-f5w6fw6q 897 5 pilot pilot NN cord-006870-f5w6fw6q 897 6 study study NN cord-006870-f5w6fw6q 897 7 was be VBD cord-006870-f5w6fw6q 897 8 initiated initiate VBN cord-006870-f5w6fw6q 897 9 within within IN cord-006870-f5w6fw6q 897 10 Intermountain Intermountain NNP cord-006870-f5w6fw6q 897 11 Healthcare Healthcare NNP cord-006870-f5w6fw6q 897 12 . . . cord-006870-f5w6fw6q 898 1 Starting start VBG cord-006870-f5w6fw6q 898 2 5/1/17 5/1/17 CD cord-006870-f5w6fw6q 898 3 , , , cord-006870-f5w6fw6q 898 4 the the DT cord-006870-f5w6fw6q 898 5 study study NN cord-006870-f5w6fw6q 898 6 included include VBD cord-006870-f5w6fw6q 898 7 all all DT cord-006870-f5w6fw6q 898 8 ischemic ischemic JJ cord-006870-f5w6fw6q 898 9 stroke stroke NN cord-006870-f5w6fw6q 898 10 patients patient NNS cord-006870-f5w6fw6q 898 11 admitted admit VBD cord-006870-f5w6fw6q 898 12 to to IN cord-006870-f5w6fw6q 898 13 the the DT cord-006870-f5w6fw6q 898 14 ICU ICU NNP cord-006870-f5w6fw6q 898 15 of of IN cord-006870-f5w6fw6q 898 16 one one CD cord-006870-f5w6fw6q 898 17 primary primary JJ cord-006870-f5w6fw6q 898 18 stroke stroke NN cord-006870-f5w6fw6q 898 19 center center NN cord-006870-f5w6fw6q 898 20 in in IN cord-006870-f5w6fw6q 898 21 Utah Utah NNP cord-006870-f5w6fw6q 898 22 . . . cord-006870-f5w6fw6q 899 1 Tele Tele NNP cord-006870-f5w6fw6q 899 2 - - HYPH cord-006870-f5w6fw6q 899 3 NCC NCC NNP cord-006870-f5w6fw6q 899 4 consultations consultation NNS cord-006870-f5w6fw6q 899 5 were be VBD cord-006870-f5w6fw6q 899 6 provided provide VBN cord-006870-f5w6fw6q 899 7 by by IN cord-006870-f5w6fw6q 899 8 NCC NCC NNP cord-006870-f5w6fw6q 899 9 physicians physician NNS cord-006870-f5w6fw6q 899 10 at at IN cord-006870-f5w6fw6q 899 11 our -PRON- PRP$ cord-006870-f5w6fw6q 899 12 flagship flagship NN cord-006870-f5w6fw6q 899 13 hospital hospital NN cord-006870-f5w6fw6q 899 14 located locate VBN cord-006870-f5w6fw6q 899 15 three three CD cord-006870-f5w6fw6q 899 16 hundred hundred CD cord-006870-f5w6fw6q 899 17 miles mile NNS cord-006870-f5w6fw6q 899 18 from from IN cord-006870-f5w6fw6q 899 19 the the DT cord-006870-f5w6fw6q 899 20 spoke spoke JJ cord-006870-f5w6fw6q 899 21 site site NN cord-006870-f5w6fw6q 899 22 . . . cord-006870-f5w6fw6q 900 1 Tele Tele NNP cord-006870-f5w6fw6q 900 2 - - HYPH cord-006870-f5w6fw6q 900 3 NCC NCC NNP cord-006870-f5w6fw6q 900 4 consultations consultation NNS cord-006870-f5w6fw6q 900 5 occurred occur VBD cord-006870-f5w6fw6q 900 6 via via IN cord-006870-f5w6fw6q 900 7 an an DT cord-006870-f5w6fw6q 900 8 existing exist VBG cord-006870-f5w6fw6q 900 9 telehealth telehealth NN cord-006870-f5w6fw6q 900 10 platform platform NN cord-006870-f5w6fw6q 900 11 developed develop VBN cord-006870-f5w6fw6q 900 12 inhouse inhouse NN cord-006870-f5w6fw6q 900 13 . . . cord-006870-f5w6fw6q 901 1 Primary primary JJ cord-006870-f5w6fw6q 901 2 outcomes outcome NNS cord-006870-f5w6fw6q 901 3 for for IN cord-006870-f5w6fw6q 901 4 this this DT cord-006870-f5w6fw6q 901 5 pilot pilot NN cord-006870-f5w6fw6q 901 6 study study NN cord-006870-f5w6fw6q 901 7 were be VBD cord-006870-f5w6fw6q 901 8 ICU ICU NNP cord-006870-f5w6fw6q 901 9 and and CC cord-006870-f5w6fw6q 901 10 hospital hospital NN cord-006870-f5w6fw6q 901 11 lengths length NNS cord-006870-f5w6fw6q 901 12 of of IN cord-006870-f5w6fw6q 901 13 stay stay NN cord-006870-f5w6fw6q 901 14 ( ( -LRB- cord-006870-f5w6fw6q 901 15 LOS LOS NNP cord-006870-f5w6fw6q 901 16 ) ) -RRB- cord-006870-f5w6fw6q 901 17 . . . cord-006870-f5w6fw6q 902 1 Secondary secondary JJ cord-006870-f5w6fw6q 902 2 outcomes outcome NNS cord-006870-f5w6fw6q 902 3 include include VBP cord-006870-f5w6fw6q 902 4 stroke stroke NN cord-006870-f5w6fw6q 902 5 complication complication NN cord-006870-f5w6fw6q 902 6 rates rate NNS cord-006870-f5w6fw6q 902 7 and and CC cord-006870-f5w6fw6q 902 8 results result NNS cord-006870-f5w6fw6q 902 9 on on IN cord-006870-f5w6fw6q 902 10 a a DT cord-006870-f5w6fw6q 902 11 provider provider NN cord-006870-f5w6fw6q 902 12 satisfaction satisfaction NN cord-006870-f5w6fw6q 902 13 questionnaire questionnaire NN cord-006870-f5w6fw6q 902 14 . . . cord-006870-f5w6fw6q 903 1 To to IN cord-006870-f5w6fw6q 903 2 date,12 date,12 NFP cord-006870-f5w6fw6q 903 3 Tele Tele NNP cord-006870-f5w6fw6q 903 4 - - HYPH cord-006870-f5w6fw6q 903 5 NCC NCC NNP cord-006870-f5w6fw6q 903 6 consultations consultation NNS cord-006870-f5w6fw6q 903 7 have have VBP cord-006870-f5w6fw6q 903 8 been be VBN cord-006870-f5w6fw6q 903 9 performed perform VBN cord-006870-f5w6fw6q 903 10 with with IN cord-006870-f5w6fw6q 903 11 median median JJ cord-006870-f5w6fw6q 903 12 hospital hospital NN cord-006870-f5w6fw6q 903 13 LOS LOS NNP cord-006870-f5w6fw6q 903 14 = = SYM cord-006870-f5w6fw6q 903 15 3 3 CD cord-006870-f5w6fw6q 903 16 days day NNS cord-006870-f5w6fw6q 903 17 ( ( -LRB- cord-006870-f5w6fw6q 903 18 IQR IQR NNP cord-006870-f5w6fw6q 903 19 2.8 2.8 CD cord-006870-f5w6fw6q 903 20 -4.3 -4.3 NFP cord-006870-f5w6fw6q 903 21 ) ) -RRB- cord-006870-f5w6fw6q 903 22 and and CC cord-006870-f5w6fw6q 903 23 ICU ICU NNP cord-006870-f5w6fw6q 903 24 LOS LOS NNP cord-006870-f5w6fw6q 903 25 = = SYM cord-006870-f5w6fw6q 903 26 1.6 1.6 CD cord-006870-f5w6fw6q 903 27 days day NNS cord-006870-f5w6fw6q 903 28 ( ( -LRB- cord-006870-f5w6fw6q 903 29 IQR IQR NNP cord-006870-f5w6fw6q 903 30 1 1 CD cord-006870-f5w6fw6q 903 31 -2 -2 CD cord-006870-f5w6fw6q 903 32 ) ) -RRB- cord-006870-f5w6fw6q 903 33 . . . cord-006870-f5w6fw6q 904 1 In in IN cord-006870-f5w6fw6q 904 2 the the DT cord-006870-f5w6fw6q 904 3 12 12 CD cord-006870-f5w6fw6q 904 4 months month NNS cord-006870-f5w6fw6q 904 5 prior prior RB cord-006870-f5w6fw6q 904 6 to to IN cord-006870-f5w6fw6q 904 7 the the DT cord-006870-f5w6fw6q 904 8 pilot pilot NN cord-006870-f5w6fw6q 904 9 , , , cord-006870-f5w6fw6q 904 10 there there EX cord-006870-f5w6fw6q 904 11 were be VBD cord-006870-f5w6fw6q 904 12 109 109 CD cord-006870-f5w6fw6q 904 13 admissions admission NNS cord-006870-f5w6fw6q 904 14 to to IN cord-006870-f5w6fw6q 904 15 the the DT cord-006870-f5w6fw6q 904 16 ICU ICU NNP cord-006870-f5w6fw6q 904 17 for for IN cord-006870-f5w6fw6q 904 18 ischemic ischemic JJ cord-006870-f5w6fw6q 904 19 stroke stroke NN cord-006870-f5w6fw6q 904 20 with with IN cord-006870-f5w6fw6q 904 21 median median JJ cord-006870-f5w6fw6q 904 22 LOS LOS NNP cord-006870-f5w6fw6q 904 23 = = SYM cord-006870-f5w6fw6q 904 24 4 4 CD cord-006870-f5w6fw6q 904 25 days day NNS cord-006870-f5w6fw6q 904 26 ( ( -LRB- cord-006870-f5w6fw6q 904 27 IQR IQR NNP cord-006870-f5w6fw6q 904 28 2.8 2.8 CD cord-006870-f5w6fw6q 904 29 -5.8 -5.8 NFP cord-006870-f5w6fw6q 904 30 ) ) -RRB- cord-006870-f5w6fw6q 904 31 and and CC cord-006870-f5w6fw6q 904 32 ICU ICU NNP cord-006870-f5w6fw6q 904 33 LOS LOS NNP cord-006870-f5w6fw6q 904 34 = = SYM cord-006870-f5w6fw6q 904 35 1.8 1.8 CD cord-006870-f5w6fw6q 904 36 ( ( -LRB- cord-006870-f5w6fw6q 904 37 IQR IQR NNP cord-006870-f5w6fw6q 904 38 1 1 CD cord-006870-f5w6fw6q 904 39 -2.6 -2.6 CD cord-006870-f5w6fw6q 904 40 ) ) -RRB- cord-006870-f5w6fw6q 904 41 . . . cord-006870-f5w6fw6q 905 1 For for IN cord-006870-f5w6fw6q 905 2 this this DT cord-006870-f5w6fw6q 905 3 small small JJ cord-006870-f5w6fw6q 905 4 sample sample NN cord-006870-f5w6fw6q 905 5 size size NN cord-006870-f5w6fw6q 905 6 , , , cord-006870-f5w6fw6q 905 7 the the DT cord-006870-f5w6fw6q 905 8 p p NN cord-006870-f5w6fw6q 905 9 - - HYPH cord-006870-f5w6fw6q 905 10 values value NNS cord-006870-f5w6fw6q 905 11 for for IN cord-006870-f5w6fw6q 905 12 comparison comparison NN cord-006870-f5w6fw6q 905 13 of of IN cord-006870-f5w6fw6q 905 14 hospital hospital NN cord-006870-f5w6fw6q 905 15 and and CC cord-006870-f5w6fw6q 905 16 ICU ICU NNP cord-006870-f5w6fw6q 905 17 lengths length NNS cord-006870-f5w6fw6q 905 18 of of IN cord-006870-f5w6fw6q 905 19 stay stay NN cord-006870-f5w6fw6q 905 20 before before RB cord-006870-f5w6fw6q 905 21 and and CC cord-006870-f5w6fw6q 905 22 after after IN cord-006870-f5w6fw6q 905 23 Tele Tele NNP cord-006870-f5w6fw6q 905 24 - - HYPH cord-006870-f5w6fw6q 905 25 NCC NCC NNP cord-006870-f5w6fw6q 905 26 are be VBP cord-006870-f5w6fw6q 905 27 0.39 0.39 CD cord-006870-f5w6fw6q 905 28 and and CC cord-006870-f5w6fw6q 905 29 0.78 0.78 CD cord-006870-f5w6fw6q 905 30 respectively respectively RB cord-006870-f5w6fw6q 905 31 . . . cord-006870-f5w6fw6q 906 1 Tele Tele NNP cord-006870-f5w6fw6q 906 2 - - HYPH cord-006870-f5w6fw6q 906 3 NCC NCC NNP cord-006870-f5w6fw6q 906 4 care care NN cord-006870-f5w6fw6q 906 5 can can MD cord-006870-f5w6fw6q 906 6 have have VB cord-006870-f5w6fw6q 906 7 significant significant JJ cord-006870-f5w6fw6q 906 8 impact impact NN cord-006870-f5w6fw6q 906 9 on on IN cord-006870-f5w6fw6q 906 10 ICU ICU NNP cord-006870-f5w6fw6q 906 11 outcomes outcome NNS cord-006870-f5w6fw6q 906 12 by by IN cord-006870-f5w6fw6q 906 13 expanding expand VBG cord-006870-f5w6fw6q 906 14 access access NN cord-006870-f5w6fw6q 906 15 to to IN cord-006870-f5w6fw6q 906 16 critical critical JJ cord-006870-f5w6fw6q 906 17 support support NN cord-006870-f5w6fw6q 906 18 from from IN cord-006870-f5w6fw6q 906 19 neurocritical neurocritical NNP cord-006870-f5w6fw6q 906 20 care care NN cord-006870-f5w6fw6q 906 21 specialists specialist NNS cord-006870-f5w6fw6q 906 22 . . . cord-006870-f5w6fw6q 907 1 Tele Tele NNP cord-006870-f5w6fw6q 907 2 - - HYPH cord-006870-f5w6fw6q 907 3 NCC NCC NNP cord-006870-f5w6fw6q 907 4 expands expand VBZ cord-006870-f5w6fw6q 907 5 access access NN cord-006870-f5w6fw6q 907 6 to to IN cord-006870-f5w6fw6q 907 7 not not RB cord-006870-f5w6fw6q 907 8 only only RB cord-006870-f5w6fw6q 907 9 consultation consultation NN cord-006870-f5w6fw6q 907 10 on on IN cord-006870-f5w6fw6q 907 11 critical critical JJ cord-006870-f5w6fw6q 907 12 neurological neurological JJ cord-006870-f5w6fw6q 907 13 emergencies emergency NNS cord-006870-f5w6fw6q 907 14 , , , cord-006870-f5w6fw6q 907 15 but but CC cord-006870-f5w6fw6q 907 16 also also RB cord-006870-f5w6fw6q 907 17 on on IN cord-006870-f5w6fw6q 907 18 when when WRB cord-006870-f5w6fw6q 907 19 to to IN cord-006870-f5w6fw6q 907 20 de de NN cord-006870-f5w6fw6q 907 21 - - VB cord-006870-f5w6fw6q 907 22 escalate escalate VB cord-006870-f5w6fw6q 907 23 from from IN cord-006870-f5w6fw6q 907 24 the the DT cord-006870-f5w6fw6q 907 25 ICU ICU NNP cord-006870-f5w6fw6q 907 26 or or CC cord-006870-f5w6fw6q 907 27 in in IN cord-006870-f5w6fw6q 907 28 end end NN cord-006870-f5w6fw6q 907 29 of of IN cord-006870-f5w6fw6q 907 30 life life NN cord-006870-f5w6fw6q 907 31 discussions discussion NNS cord-006870-f5w6fw6q 907 32 with with IN cord-006870-f5w6fw6q 907 33 which which WDT cord-006870-f5w6fw6q 907 34 general general JJ cord-006870-f5w6fw6q 907 35 ICU ICU NNP cord-006870-f5w6fw6q 907 36 teams team NNS cord-006870-f5w6fw6q 907 37 may may MD cord-006870-f5w6fw6q 907 38 not not RB cord-006870-f5w6fw6q 907 39 be be VB cord-006870-f5w6fw6q 907 40 comfortable comfortable JJ cord-006870-f5w6fw6q 907 41 . . . cord-006870-f5w6fw6q 908 1 These these DT cord-006870-f5w6fw6q 908 2 impacts impact NNS cord-006870-f5w6fw6q 908 3 could could MD cord-006870-f5w6fw6q 908 4 be be VB cord-006870-f5w6fw6q 908 5 measured measure VBN cord-006870-f5w6fw6q 908 6 as as IN cord-006870-f5w6fw6q 908 7 important important JJ cord-006870-f5w6fw6q 908 8 decreases decrease NNS cord-006870-f5w6fw6q 908 9 in in IN cord-006870-f5w6fw6q 908 10 hospital hospital NN cord-006870-f5w6fw6q 908 11 and and CC cord-006870-f5w6fw6q 908 12 ICU ICU NNP cord-006870-f5w6fw6q 908 13 LOS LOS NNP cord-006870-f5w6fw6q 908 14 . . . cord-006870-f5w6fw6q 909 1 Hospital hospital NN cord-006870-f5w6fw6q 909 2 readmissions readmission NNS cord-006870-f5w6fw6q 909 3 increase increase VBP cord-006870-f5w6fw6q 909 4 health health NN cord-006870-f5w6fw6q 909 5 care care NN cord-006870-f5w6fw6q 909 6 costs cost NNS cord-006870-f5w6fw6q 909 7 , , , cord-006870-f5w6fw6q 909 8 increase increase VB cord-006870-f5w6fw6q 909 9 patient patient JJ cord-006870-f5w6fw6q 909 10 exposure exposure NN cord-006870-f5w6fw6q 909 11 to to IN cord-006870-f5w6fw6q 909 12 nosocomial nosocomial JJ cord-006870-f5w6fw6q 909 13 disease disease NN cord-006870-f5w6fw6q 909 14 , , , cord-006870-f5w6fw6q 909 15 and and CC cord-006870-f5w6fw6q 909 16 imply imply VB cord-006870-f5w6fw6q 909 17 patients patient NNS cord-006870-f5w6fw6q 909 18 were be VBD cord-006870-f5w6fw6q 909 19 not not RB cord-006870-f5w6fw6q 909 20 stable stable JJ cord-006870-f5w6fw6q 909 21 for for IN cord-006870-f5w6fw6q 909 22 discharge discharge NN cord-006870-f5w6fw6q 909 23 . . . cord-006870-f5w6fw6q 910 1 Because because IN cord-006870-f5w6fw6q 910 2 readmissions readmission NNS cord-006870-f5w6fw6q 910 3 are be VBP cord-006870-f5w6fw6q 910 4 a a DT cord-006870-f5w6fw6q 910 5 target target NN cord-006870-f5w6fw6q 910 6 for for IN cord-006870-f5w6fw6q 910 7 hospitals hospital NNS cord-006870-f5w6fw6q 910 8 and and CC cord-006870-f5w6fw6q 910 9 payers payer NNS cord-006870-f5w6fw6q 910 10 , , , cord-006870-f5w6fw6q 910 11 several several JJ cord-006870-f5w6fw6q 910 12 centers center NNS cord-006870-f5w6fw6q 910 13 have have VBP cord-006870-f5w6fw6q 910 14 developed develop VBN cord-006870-f5w6fw6q 910 15 predictive predictive JJ cord-006870-f5w6fw6q 910 16 readmission readmission NN cord-006870-f5w6fw6q 910 17 scores score NNS cord-006870-f5w6fw6q 910 18 in in IN cord-006870-f5w6fw6q 910 19 order order NN cord-006870-f5w6fw6q 910 20 to to TO cord-006870-f5w6fw6q 910 21 identify identify VB cord-006870-f5w6fw6q 910 22 high high JJ cord-006870-f5w6fw6q 910 23 - - HYPH cord-006870-f5w6fw6q 910 24 risk risk NN cord-006870-f5w6fw6q 910 25 patients patient NNS cord-006870-f5w6fw6q 910 26 . . . cord-006870-f5w6fw6q 911 1 We -PRON- PRP cord-006870-f5w6fw6q 911 2 contend contend VBP cord-006870-f5w6fw6q 911 3 that that IN cord-006870-f5w6fw6q 911 4 these these DT cord-006870-f5w6fw6q 911 5 general general JJ cord-006870-f5w6fw6q 911 6 readmission readmission NN cord-006870-f5w6fw6q 911 7 scores score NNS cord-006870-f5w6fw6q 911 8 are be VBP cord-006870-f5w6fw6q 911 9 not not RB cord-006870-f5w6fw6q 911 10 suitable suitable JJ cord-006870-f5w6fw6q 911 11 for for IN cord-006870-f5w6fw6q 911 12 neurocritically neurocritically RB cord-006870-f5w6fw6q 911 13 ill ill JJ cord-006870-f5w6fw6q 911 14 patients patient NNS cord-006870-f5w6fw6q 911 15 and and CC cord-006870-f5w6fw6q 911 16 that that DT cord-006870-f5w6fw6q 911 17 specific specific JJ cord-006870-f5w6fw6q 911 18 predictive predictive JJ cord-006870-f5w6fw6q 911 19 score score NN cord-006870-f5w6fw6q 911 20 must must MD cord-006870-f5w6fw6q 911 21 be be VB cord-006870-f5w6fw6q 911 22 developed develop VBN cord-006870-f5w6fw6q 911 23 to to TO cord-006870-f5w6fw6q 911 24 identify identify VB cord-006870-f5w6fw6q 911 25 high high JJ cord-006870-f5w6fw6q 911 26 - - HYPH cord-006870-f5w6fw6q 911 27 risk risk NN cord-006870-f5w6fw6q 911 28 patients patient NNS cord-006870-f5w6fw6q 911 29 . . . cord-006870-f5w6fw6q 912 1 We -PRON- PRP cord-006870-f5w6fw6q 912 2 conducted conduct VBD cord-006870-f5w6fw6q 912 3 a a DT cord-006870-f5w6fw6q 912 4 retrospective retrospective JJ cord-006870-f5w6fw6q 912 5 chart chart NN cord-006870-f5w6fw6q 912 6 review review NN cord-006870-f5w6fw6q 912 7 of of IN cord-006870-f5w6fw6q 912 8 340 340 CD cord-006870-f5w6fw6q 912 9 consecutive consecutive JJ cord-006870-f5w6fw6q 912 10 patients patient NNS cord-006870-f5w6fw6q 912 11 admitted admit VBN cord-006870-f5w6fw6q 912 12 to to IN cord-006870-f5w6fw6q 912 13 our -PRON- PRP$ cord-006870-f5w6fw6q 912 14 neuroscience neuroscience NN cord-006870-f5w6fw6q 912 15 critical critical JJ cord-006870-f5w6fw6q 912 16 care care NN cord-006870-f5w6fw6q 912 17 unit unit NN cord-006870-f5w6fw6q 912 18 . . . cord-006870-f5w6fw6q 913 1 We -PRON- PRP cord-006870-f5w6fw6q 913 2 recorded record VBD cord-006870-f5w6fw6q 913 3 the the DT cord-006870-f5w6fw6q 913 4 readmission readmission NN cord-006870-f5w6fw6q 913 5 scores score NNS cord-006870-f5w6fw6q 913 6 , , , cord-006870-f5w6fw6q 913 7 reason reason NN cord-006870-f5w6fw6q 913 8 for for IN cord-006870-f5w6fw6q 913 9 admission admission NN cord-006870-f5w6fw6q 913 10 , , , cord-006870-f5w6fw6q 913 11 length length NN cord-006870-f5w6fw6q 913 12 of of IN cord-006870-f5w6fw6q 913 13 stay stay NN cord-006870-f5w6fw6q 913 14 , , , cord-006870-f5w6fw6q 913 15 and and CC cord-006870-f5w6fw6q 913 16 if if IN cord-006870-f5w6fw6q 913 17 they -PRON- PRP cord-006870-f5w6fw6q 913 18 were be VBD cord-006870-f5w6fw6q 913 19 readmitted readmitte VBN cord-006870-f5w6fw6q 913 20 . . . cord-006870-f5w6fw6q 914 1 We -PRON- PRP cord-006870-f5w6fw6q 914 2 then then RB cord-006870-f5w6fw6q 914 3 compared compare VBD cord-006870-f5w6fw6q 914 4 the the DT cord-006870-f5w6fw6q 914 5 median median NN cord-006870-f5w6fw6q 914 6 readmission readmission NN cord-006870-f5w6fw6q 914 7 scores score NNS cord-006870-f5w6fw6q 914 8 between between IN cord-006870-f5w6fw6q 914 9 the the DT cord-006870-f5w6fw6q 914 10 two two CD cord-006870-f5w6fw6q 914 11 groups group NNS cord-006870-f5w6fw6q 914 12 . . . cord-006870-f5w6fw6q 915 1 After after IN cord-006870-f5w6fw6q 915 2 removing remove VBG cord-006870-f5w6fw6q 915 3 patients patient NNS cord-006870-f5w6fw6q 915 4 without without IN cord-006870-f5w6fw6q 915 5 readmission readmission NN cord-006870-f5w6fw6q 915 6 scores score NNS cord-006870-f5w6fw6q 915 7 or or CC cord-006870-f5w6fw6q 915 8 died die VBD cord-006870-f5w6fw6q 915 9 at at IN cord-006870-f5w6fw6q 915 10 the the DT cord-006870-f5w6fw6q 915 11 end end NN cord-006870-f5w6fw6q 915 12 of of IN cord-006870-f5w6fw6q 915 13 the the DT cord-006870-f5w6fw6q 915 14 original original JJ cord-006870-f5w6fw6q 915 15 admission admission NN cord-006870-f5w6fw6q 915 16 , , , cord-006870-f5w6fw6q 915 17 we -PRON- PRP cord-006870-f5w6fw6q 915 18 analyzed analyze VBD cord-006870-f5w6fw6q 915 19 the the DT cord-006870-f5w6fw6q 915 20 records record NNS cord-006870-f5w6fw6q 915 21 of of IN cord-006870-f5w6fw6q 915 22 279 279 CD cord-006870-f5w6fw6q 915 23 patients patient NNS cord-006870-f5w6fw6q 915 24 . . . cord-006870-f5w6fw6q 916 1 Patients patient NNS cord-006870-f5w6fw6q 916 2 were be VBD cord-006870-f5w6fw6q 916 3 more more RBR cord-006870-f5w6fw6q 916 4 likely likely JJ cord-006870-f5w6fw6q 916 5 to to TO cord-006870-f5w6fw6q 916 6 be be VB cord-006870-f5w6fw6q 916 7 readmitted readmitte VBN cord-006870-f5w6fw6q 916 8 if if IN cord-006870-f5w6fw6q 916 9 they -PRON- PRP cord-006870-f5w6fw6q 916 10 were be VBD cord-006870-f5w6fw6q 916 11 initially initially RB cord-006870-f5w6fw6q 916 12 emergently emergently RB cord-006870-f5w6fw6q 916 13 hospitalized hospitalize VBN cord-006870-f5w6fw6q 916 14 or or CC cord-006870-f5w6fw6q 916 15 had have VBD cord-006870-f5w6fw6q 916 16 malignancy malignancy NN cord-006870-f5w6fw6q 916 17 . . . cord-006870-f5w6fw6q 917 1 Readmitted readmitte VBN cord-006870-f5w6fw6q 917 2 patients patient NNS cord-006870-f5w6fw6q 917 3 had have VBD cord-006870-f5w6fw6q 917 4 a a DT cord-006870-f5w6fw6q 917 5 longer long RBR cord-006870-f5w6fw6q 917 6 original original JJ cord-006870-f5w6fw6q 917 7 hospital hospital NN cord-006870-f5w6fw6q 917 8 length length NN cord-006870-f5w6fw6q 917 9 of of IN cord-006870-f5w6fw6q 917 10 stay stay NN cord-006870-f5w6fw6q 917 11 . . . cord-006870-f5w6fw6q 918 1 We -PRON- PRP cord-006870-f5w6fw6q 918 2 found find VBD cord-006870-f5w6fw6q 918 3 no no DT cord-006870-f5w6fw6q 918 4 difference difference NN cord-006870-f5w6fw6q 918 5 median median JJ cord-006870-f5w6fw6q 918 6 readmission readmission NN cord-006870-f5w6fw6q 918 7 score score NN cord-006870-f5w6fw6q 918 8 between between IN cord-006870-f5w6fw6q 918 9 those those DT cord-006870-f5w6fw6q 918 10 who who WP cord-006870-f5w6fw6q 918 11 were be VBD cord-006870-f5w6fw6q 918 12 readmitted readmitte VBN cord-006870-f5w6fw6q 918 13 , , , cord-006870-f5w6fw6q 918 14 and and CC cord-006870-f5w6fw6q 918 15 those those DT cord-006870-f5w6fw6q 918 16 who who WP cord-006870-f5w6fw6q 918 17 were be VBD cord-006870-f5w6fw6q 918 18 not not RB cord-006870-f5w6fw6q 918 19 . . . cord-006870-f5w6fw6q 919 1 Most most RBS cord-006870-f5w6fw6q 919 2 readmitted readmitte VBN cord-006870-f5w6fw6q 919 3 patients patient NNS cord-006870-f5w6fw6q 919 4 ( ( -LRB- cord-006870-f5w6fw6q 919 5 65.8 65.8 CD cord-006870-f5w6fw6q 919 6 % % NN cord-006870-f5w6fw6q 919 7 ) ) -RRB- cord-006870-f5w6fw6q 919 8 had have VBD cord-006870-f5w6fw6q 919 9 an an DT cord-006870-f5w6fw6q 919 10 original original JJ cord-006870-f5w6fw6q 919 11 " " `` cord-006870-f5w6fw6q 919 12 low low JJ cord-006870-f5w6fw6q 919 13 - - HYPH cord-006870-f5w6fw6q 919 14 risk risk NN cord-006870-f5w6fw6q 919 15 " " '' cord-006870-f5w6fw6q 919 16 readmission readmission NN cord-006870-f5w6fw6q 919 17 score score NN cord-006870-f5w6fw6q 919 18 . . . cord-006870-f5w6fw6q 920 1 We -PRON- PRP cord-006870-f5w6fw6q 920 2 found find VBD cord-006870-f5w6fw6q 920 3 that that IN cord-006870-f5w6fw6q 920 4 our -PRON- PRP$ cord-006870-f5w6fw6q 920 5 center center NN cord-006870-f5w6fw6q 920 6 's 's POS cord-006870-f5w6fw6q 920 7 score score NN cord-006870-f5w6fw6q 920 8 was be VBD cord-006870-f5w6fw6q 920 9 poor poor JJ cord-006870-f5w6fw6q 920 10 in in IN cord-006870-f5w6fw6q 920 11 predicting predict VBG cord-006870-f5w6fw6q 920 12 readmission readmission NN cord-006870-f5w6fw6q 920 13 for for IN cord-006870-f5w6fw6q 920 14 neurocritical neurocritical JJ cord-006870-f5w6fw6q 920 15 care care NN cord-006870-f5w6fw6q 920 16 patients patient NNS cord-006870-f5w6fw6q 920 17 and and CC cord-006870-f5w6fw6q 920 18 that that IN cord-006870-f5w6fw6q 920 19 several several JJ cord-006870-f5w6fw6q 920 20 components component NNS cord-006870-f5w6fw6q 920 21 of of IN cord-006870-f5w6fw6q 920 22 the the DT cord-006870-f5w6fw6q 920 23 score score NN cord-006870-f5w6fw6q 920 24 do do VBP cord-006870-f5w6fw6q 920 25 not not RB cord-006870-f5w6fw6q 920 26 apply apply VB cord-006870-f5w6fw6q 920 27 to to IN cord-006870-f5w6fw6q 920 28 our -PRON- PRP$ cord-006870-f5w6fw6q 920 29 patient patient JJ cord-006870-f5w6fw6q 920 30 population population NN cord-006870-f5w6fw6q 920 31 . . . cord-006870-f5w6fw6q 921 1 We -PRON- PRP cord-006870-f5w6fw6q 921 2 propose propose VBP cord-006870-f5w6fw6q 921 3 that that DT cord-006870-f5w6fw6q 921 4 to to TO cord-006870-f5w6fw6q 921 5 accurately accurately RB cord-006870-f5w6fw6q 921 6 predict predict VB cord-006870-f5w6fw6q 921 7 readmission readmission NN cord-006870-f5w6fw6q 921 8 , , , cord-006870-f5w6fw6q 921 9 centers center NNS cord-006870-f5w6fw6q 921 10 should should MD cord-006870-f5w6fw6q 921 11 create create VB cord-006870-f5w6fw6q 921 12 their -PRON- PRP$ cord-006870-f5w6fw6q 921 13 own own JJ cord-006870-f5w6fw6q 921 14 unique unique JJ cord-006870-f5w6fw6q 921 15 readmission readmission NN cord-006870-f5w6fw6q 921 16 scores score NNS cord-006870-f5w6fw6q 921 17 for for IN cord-006870-f5w6fw6q 921 18 more more RBR cord-006870-f5w6fw6q 921 19 homogeneous homogeneous JJ cord-006870-f5w6fw6q 921 20 admission admission NN cord-006870-f5w6fw6q 921 21 populations population NNS cord-006870-f5w6fw6q 921 22 . . . cord-006870-f5w6fw6q 922 1 Clinical clinical JJ cord-006870-f5w6fw6q 922 2 evaluation evaluation NN cord-006870-f5w6fw6q 922 3 of of IN cord-006870-f5w6fw6q 922 4 the the DT cord-006870-f5w6fw6q 922 5 level level NN cord-006870-f5w6fw6q 922 6 of of IN cord-006870-f5w6fw6q 922 7 consciousness consciousness NN cord-006870-f5w6fw6q 922 8 in in IN cord-006870-f5w6fw6q 922 9 non non JJ cord-006870-f5w6fw6q 922 10 - - JJ cord-006870-f5w6fw6q 922 11 communicative communicative JJ cord-006870-f5w6fw6q 922 12 patients patient NNS cord-006870-f5w6fw6q 922 13 can can MD cord-006870-f5w6fw6q 922 14 be be VB cord-006870-f5w6fw6q 922 15 very very RB cord-006870-f5w6fw6q 922 16 challenging challenging JJ cord-006870-f5w6fw6q 922 17 . . . cord-006870-f5w6fw6q 923 1 In in IN cord-006870-f5w6fw6q 923 2 this this DT cord-006870-f5w6fw6q 923 3 study study NN cord-006870-f5w6fw6q 923 4 , , , cord-006870-f5w6fw6q 923 5 we -PRON- PRP cord-006870-f5w6fw6q 923 6 aimed aim VBD cord-006870-f5w6fw6q 923 7 to to TO cord-006870-f5w6fw6q 923 8 evaluate evaluate VB cord-006870-f5w6fw6q 923 9 the the DT cord-006870-f5w6fw6q 923 10 nurses nurse NNS cord-006870-f5w6fw6q 923 11 and and CC cord-006870-f5w6fw6q 923 12 nursing nursing NN cord-006870-f5w6fw6q 923 13 assistants assistant NNS cord-006870-f5w6fw6q 923 14 ' ' POS cord-006870-f5w6fw6q 923 15 ( ( -LRB- cord-006870-f5w6fw6q 923 16 NAs NAs NNP cord-006870-f5w6fw6q 923 17 ) ) -RRB- cord-006870-f5w6fw6q 923 18 perception perception NN cord-006870-f5w6fw6q 923 19 of of IN cord-006870-f5w6fw6q 923 20 the the DT cord-006870-f5w6fw6q 923 21 consciousness consciousness NN cord-006870-f5w6fw6q 923 22 on on IN cord-006870-f5w6fw6q 923 23 patients patient NNS cord-006870-f5w6fw6q 923 24 suffering suffer VBG cord-006870-f5w6fw6q 923 25 from from IN cord-006870-f5w6fw6q 923 26 disorder disorder NN cord-006870-f5w6fw6q 923 27 of of IN cord-006870-f5w6fw6q 923 28 consciousness consciousness NN cord-006870-f5w6fw6q 923 29 ( ( -LRB- cord-006870-f5w6fw6q 923 30 DOC DOC NNP cord-006870-f5w6fw6q 923 31 ) ) -RRB- cord-006870-f5w6fw6q 923 32 . . . cord-006870-f5w6fw6q 924 1 Through through IN cord-006870-f5w6fw6q 924 2 their -PRON- PRP$ cord-006870-f5w6fw6q 924 3 activities activity NNS cord-006870-f5w6fw6q 924 4 , , , cord-006870-f5w6fw6q 924 5 nurses nurse NNS cord-006870-f5w6fw6q 924 6 and and CC cord-006870-f5w6fw6q 924 7 NAs NAs NNPS cord-006870-f5w6fw6q 924 8 have have VBP cord-006870-f5w6fw6q 924 9 an an DT cord-006870-f5w6fw6q 924 10 extended extended JJ cord-006870-f5w6fw6q 924 11 observation observation NN cord-006870-f5w6fw6q 924 12 time time NN cord-006870-f5w6fw6q 924 13 of of IN cord-006870-f5w6fw6q 924 14 patient patient NN cord-006870-f5w6fw6q 924 15 's 's POS cord-006870-f5w6fw6q 924 16 behavior behavior NN cord-006870-f5w6fw6q 924 17 , , , cord-006870-f5w6fw6q 924 18 and and CC cord-006870-f5w6fw6q 924 19 make make VB cord-006870-f5w6fw6q 924 20 repeated repeat VBN cord-006870-f5w6fw6q 924 21 implicit implicit JJ cord-006870-f5w6fw6q 924 22 assessments assessment NNS cord-006870-f5w6fw6q 924 23 of of IN cord-006870-f5w6fw6q 924 24 patients patient NNS cord-006870-f5w6fw6q 924 25 ' ' POS cord-006870-f5w6fw6q 924 26 clinical clinical JJ cord-006870-f5w6fw6q 924 27 state state NN cord-006870-f5w6fw6q 924 28 of of IN cord-006870-f5w6fw6q 924 29 consciousness consciousness NN cord-006870-f5w6fw6q 924 30 . . . cord-006870-f5w6fw6q 925 1 We -PRON- PRP cord-006870-f5w6fw6q 925 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 925 3 that that IN cord-006870-f5w6fw6q 925 4 even even RB cord-006870-f5w6fw6q 925 5 in in IN cord-006870-f5w6fw6q 925 6 the the DT cord-006870-f5w6fw6q 925 7 absence absence NN cord-006870-f5w6fw6q 925 8 of of IN cord-006870-f5w6fw6q 925 9 a a DT cord-006870-f5w6fw6q 925 10 structured structured JJ cord-006870-f5w6fw6q 925 11 and and CC cord-006870-f5w6fw6q 925 12 explicit explicit JJ cord-006870-f5w6fw6q 925 13 evaluation evaluation NN cord-006870-f5w6fw6q 925 14 of of IN cord-006870-f5w6fw6q 925 15 consciousness consciousness NN cord-006870-f5w6fw6q 925 16 ( ( -LRB- cord-006870-f5w6fw6q 925 17 in in IN cord-006870-f5w6fw6q 925 18 contrast contrast NN cord-006870-f5w6fw6q 925 19 for for IN cord-006870-f5w6fw6q 925 20 instance instance NN cord-006870-f5w6fw6q 925 21 with with IN cord-006870-f5w6fw6q 925 22 the the DT cord-006870-f5w6fw6q 925 23 Coma Coma NNP cord-006870-f5w6fw6q 925 24 Recovery Recovery NNP cord-006870-f5w6fw6q 925 25 Scale Scale NNP cord-006870-f5w6fw6q 925 26 Revised revise VBD cord-006870-f5w6fw6q 925 27 -CRS -CRS : cord-006870-f5w6fw6q 925 28 - - HYPH cord-006870-f5w6fw6q 925 29 R r NN cord-006870-f5w6fw6q 925 30 ) ) -RRB- cord-006870-f5w6fw6q 925 31 , , , cord-006870-f5w6fw6q 925 32 nursing nursing NN cord-006870-f5w6fw6q 925 33 expertise expertise NN cord-006870-f5w6fw6q 925 34 could could MD cord-006870-f5w6fw6q 925 35 be be VB cord-006870-f5w6fw6q 925 36 a a DT cord-006870-f5w6fw6q 925 37 valuable valuable JJ cord-006870-f5w6fw6q 925 38 measure measure NN cord-006870-f5w6fw6q 925 39 to to TO cord-006870-f5w6fw6q 925 40 improve improve VB cord-006870-f5w6fw6q 925 41 assessment assessment NN cord-006870-f5w6fw6q 925 42 of of IN cord-006870-f5w6fw6q 925 43 state state NN cord-006870-f5w6fw6q 925 44 of of IN cord-006870-f5w6fw6q 925 45 consciousness consciousness NN cord-006870-f5w6fw6q 925 46 in in IN cord-006870-f5w6fw6q 925 47 DOC doc NN cord-006870-f5w6fw6q 925 48 patients patient NNS cord-006870-f5w6fw6q 925 49 . . . cord-006870-f5w6fw6q 926 1 This this DT cord-006870-f5w6fw6q 926 2 was be VBD cord-006870-f5w6fw6q 926 3 a a DT cord-006870-f5w6fw6q 926 4 prospective prospective JJ cord-006870-f5w6fw6q 926 5 observational observational JJ cord-006870-f5w6fw6q 926 6 single single JJ cord-006870-f5w6fw6q 926 7 - - HYPH cord-006870-f5w6fw6q 926 8 center center NN cord-006870-f5w6fw6q 926 9 study study NN cord-006870-f5w6fw6q 926 10 . . . cord-006870-f5w6fw6q 927 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 927 2 primary primary JJ cord-006870-f5w6fw6q 927 3 objective objective NN cord-006870-f5w6fw6q 927 4 was be VBD cord-006870-f5w6fw6q 927 5 to to TO cord-006870-f5w6fw6q 927 6 correlate correlate VB cord-006870-f5w6fw6q 927 7 the the DT cord-006870-f5w6fw6q 927 8 nurses nurse NNS cord-006870-f5w6fw6q 927 9 and and CC cord-006870-f5w6fw6q 927 10 NA NA NNP cord-006870-f5w6fw6q 927 11 's 's POS cord-006870-f5w6fw6q 927 12 assessment assessment NN cord-006870-f5w6fw6q 927 13 of of IN cord-006870-f5w6fw6q 927 14 DOC doc NN cord-006870-f5w6fw6q 927 15 - - HYPH cord-006870-f5w6fw6q 927 16 patients patient NNS cord-006870-f5w6fw6q 927 17 ' ' POS cord-006870-f5w6fw6q 927 18 consciousness consciousness NN cord-006870-f5w6fw6q 927 19 quantified quantify VBN cord-006870-f5w6fw6q 927 20 through through IN cord-006870-f5w6fw6q 927 21 an an DT cord-006870-f5w6fw6q 927 22 Analogic analogic JJ cord-006870-f5w6fw6q 927 23 Visual visual JJ cord-006870-f5w6fw6q 927 24 Scale scale NN cord-006870-f5w6fw6q 927 25 ( ( -LRB- cord-006870-f5w6fw6q 927 26 the the DT cord-006870-f5w6fw6q 927 27 " " `` cord-006870-f5w6fw6q 927 28 DOC doc NN cord-006870-f5w6fw6q 927 29 - - HYPH cord-006870-f5w6fw6q 927 30 feeling feeling NN cord-006870-f5w6fw6q 927 31 score score NN cord-006870-f5w6fw6q 927 32 " " '' cord-006870-f5w6fw6q 927 33 ) ) -RRB- cord-006870-f5w6fw6q 927 34 with with IN cord-006870-f5w6fw6q 927 35 the the DT cord-006870-f5w6fw6q 927 36 results result NNS cord-006870-f5w6fw6q 927 37 of of IN cord-006870-f5w6fw6q 927 38 the the DT cord-006870-f5w6fw6q 927 39 standard standard JJ cord-006870-f5w6fw6q 927 40 methods method NNS cord-006870-f5w6fw6q 927 41 ( ( -LRB- cord-006870-f5w6fw6q 927 42 including include VBG cord-006870-f5w6fw6q 927 43 CRS CRS NNP cord-006870-f5w6fw6q 927 44 - - HYPH cord-006870-f5w6fw6q 927 45 R R NNP cord-006870-f5w6fw6q 927 46 , , , cord-006870-f5w6fw6q 927 47 fMRI fMRI NNP cord-006870-f5w6fw6q 927 48 , , , cord-006870-f5w6fw6q 927 49 electrophysiology electrophysiology NNP cord-006870-f5w6fw6q 927 50 ) ) -RRB- cord-006870-f5w6fw6q 927 51 . . . cord-006870-f5w6fw6q 928 1 The the DT cord-006870-f5w6fw6q 928 2 secondary secondary JJ cord-006870-f5w6fw6q 928 3 objective objective NN cord-006870-f5w6fw6q 928 4 was be VBD cord-006870-f5w6fw6q 928 5 to to TO cord-006870-f5w6fw6q 928 6 identify identify VB cord-006870-f5w6fw6q 928 7 elements element NNS cord-006870-f5w6fw6q 928 8 which which WDT cord-006870-f5w6fw6q 928 9 correlate correlate VBP cord-006870-f5w6fw6q 928 10 with with IN cord-006870-f5w6fw6q 928 11 this this DT cord-006870-f5w6fw6q 928 12 assessment assessment NN cord-006870-f5w6fw6q 928 13 and/or and/or CC cord-006870-f5w6fw6q 928 14 with with IN cord-006870-f5w6fw6q 928 15 the the DT cord-006870-f5w6fw6q 928 16 expert expert NN cord-006870-f5w6fw6q 928 17 's 's POS cord-006870-f5w6fw6q 928 18 diagnosis diagnosis NN cord-006870-f5w6fw6q 928 19 ( ( -LRB- cord-006870-f5w6fw6q 928 20 such such JJ cord-006870-f5w6fw6q 928 21 as as IN cord-006870-f5w6fw6q 928 22 visual visual JJ cord-006870-f5w6fw6q 928 23 pursuit pursuit NN cord-006870-f5w6fw6q 928 24 , , , cord-006870-f5w6fw6q 928 25 patient patient NN cord-006870-f5w6fw6q 928 26 's 's POS cord-006870-f5w6fw6q 928 27 participation participation NN cord-006870-f5w6fw6q 928 28 to to IN cord-006870-f5w6fw6q 928 29 nursing nursing NN cord-006870-f5w6fw6q 928 30 , , , cord-006870-f5w6fw6q 928 31 motor motor NN cord-006870-f5w6fw6q 928 32 responses response NNS cord-006870-f5w6fw6q 928 33 to to IN cord-006870-f5w6fw6q 928 34 verbal verbal JJ cord-006870-f5w6fw6q 928 35 command command NN cord-006870-f5w6fw6q 928 36 or or CC cord-006870-f5w6fw6q 928 37 adapted adapt VBN cord-006870-f5w6fw6q 928 38 reactions reaction NNS cord-006870-f5w6fw6q 928 39 to to IN cord-006870-f5w6fw6q 928 40 painful painful JJ cord-006870-f5w6fw6q 928 41 care care NN cord-006870-f5w6fw6q 928 42 ) ) -RRB- cord-006870-f5w6fw6q 928 43 . . . cord-006870-f5w6fw6q 928 44 . . . cord-006870-f5w6fw6q 929 1 Linear linear JJ cord-006870-f5w6fw6q 929 2 regression regression NN cord-006870-f5w6fw6q 929 3 reveals reveal VBZ cord-006870-f5w6fw6q 929 4 a a DT cord-006870-f5w6fw6q 929 5 good good JJ cord-006870-f5w6fw6q 929 6 correlation correlation NN cord-006870-f5w6fw6q 929 7 between between IN cord-006870-f5w6fw6q 929 8 the the DT cord-006870-f5w6fw6q 929 9 " " `` cord-006870-f5w6fw6q 929 10 DOC doc NN cord-006870-f5w6fw6q 929 11 - - HYPH cord-006870-f5w6fw6q 929 12 feeling feeling NN cord-006870-f5w6fw6q 929 13 score score NN cord-006870-f5w6fw6q 929 14 " " '' cord-006870-f5w6fw6q 929 15 and and CC cord-006870-f5w6fw6q 929 16 the the DT cord-006870-f5w6fw6q 929 17 CRS CRS NNP cord-006870-f5w6fw6q 929 18 - - HYPH cord-006870-f5w6fw6q 929 19 R R NNP cord-006870-f5w6fw6q 929 20 gold gold NN cord-006870-f5w6fw6q 929 21 standard standard NN cord-006870-f5w6fw6q 929 22 ( ( -LRB- cord-006870-f5w6fw6q 929 23 R2 R2 NNP cord-006870-f5w6fw6q 929 24 = = SYM cord-006870-f5w6fw6q 929 25 0.37 0.37 CD cord-006870-f5w6fw6q 929 26 , , , cord-006870-f5w6fw6q 929 27 p p NN cord-006870-f5w6fw6q 929 28 - - HYPH cord-006870-f5w6fw6q 929 29 value value NN cord-006870-f5w6fw6q 929 30 < < NNP cord-006870-f5w6fw6q 929 31 0.0002 0.0002 CD cord-006870-f5w6fw6q 929 32 , , , cord-006870-f5w6fw6q 929 33 Figure figure NN cord-006870-f5w6fw6q 929 34 2 2 CD cord-006870-f5w6fw6q 929 35 ) ) -RRB- cord-006870-f5w6fw6q 929 36 . . . cord-006870-f5w6fw6q 930 1 Global global JJ cord-006870-f5w6fw6q 930 2 assessment assessment NN cord-006870-f5w6fw6q 930 3 of of IN cord-006870-f5w6fw6q 930 4 the the DT cord-006870-f5w6fw6q 930 5 level level NN cord-006870-f5w6fw6q 930 6 of of IN cord-006870-f5w6fw6q 930 7 consciousness consciousness NN cord-006870-f5w6fw6q 930 8 by by IN cord-006870-f5w6fw6q 930 9 all all PDT cord-006870-f5w6fw6q 930 10 the the DT cord-006870-f5w6fw6q 930 11 caregivers caregiver NNS cord-006870-f5w6fw6q 930 12 interacting interact VBG cord-006870-f5w6fw6q 930 13 with with IN cord-006870-f5w6fw6q 930 14 the the DT cord-006870-f5w6fw6q 930 15 patient patient NN cord-006870-f5w6fw6q 930 16 using use VBG cord-006870-f5w6fw6q 930 17 the the DT cord-006870-f5w6fw6q 930 18 " " `` cord-006870-f5w6fw6q 930 19 DOC doc NN cord-006870-f5w6fw6q 930 20 - - HYPH cord-006870-f5w6fw6q 930 21 feeling feeling NN cord-006870-f5w6fw6q 930 22 score score NN cord-006870-f5w6fw6q 930 23 " " '' cord-006870-f5w6fw6q 930 24 is be VBZ cord-006870-f5w6fw6q 930 25 reliable reliable JJ cord-006870-f5w6fw6q 930 26 and and CC cord-006870-f5w6fw6q 930 27 can can MD cord-006870-f5w6fw6q 930 28 improve improve VB cord-006870-f5w6fw6q 930 29 assessment assessment NN cord-006870-f5w6fw6q 930 30 of of IN cord-006870-f5w6fw6q 930 31 state state NN cord-006870-f5w6fw6q 930 32 of of IN cord-006870-f5w6fw6q 930 33 consciousness consciousness NN cord-006870-f5w6fw6q 930 34 in in IN cord-006870-f5w6fw6q 930 35 DOC doc NN cord-006870-f5w6fw6q 930 36 patients patient NNS cord-006870-f5w6fw6q 930 37 . . . cord-006870-f5w6fw6q 931 1 Investigating investigate VBG cord-006870-f5w6fw6q 931 2 causes cause NNS cord-006870-f5w6fw6q 931 3 of of IN cord-006870-f5w6fw6q 931 4 deterioration deterioration NN cord-006870-f5w6fw6q 931 5 in in IN cord-006870-f5w6fw6q 931 6 neurological neurological JJ cord-006870-f5w6fw6q 931 7 patients patient NNS cord-006870-f5w6fw6q 931 8 is be VBZ cord-006870-f5w6fw6q 931 9 important important JJ cord-006870-f5w6fw6q 931 10 to to TO cord-006870-f5w6fw6q 931 11 anticipate anticipate VB cord-006870-f5w6fw6q 931 12 these these DT cord-006870-f5w6fw6q 931 13 complications complication NNS cord-006870-f5w6fw6q 931 14 and and CC cord-006870-f5w6fw6q 931 15 improve improve VB cord-006870-f5w6fw6q 931 16 outcomes outcome NNS cord-006870-f5w6fw6q 931 17 . . . cord-006870-f5w6fw6q 932 1 This this DT cord-006870-f5w6fw6q 932 2 is be VBZ cord-006870-f5w6fw6q 932 3 a a DT cord-006870-f5w6fw6q 932 4 prospective prospective JJ cord-006870-f5w6fw6q 932 5 observational observational JJ cord-006870-f5w6fw6q 932 6 study study NN cord-006870-f5w6fw6q 932 7 performed perform VBN cord-006870-f5w6fw6q 932 8 at at IN cord-006870-f5w6fw6q 932 9 an an DT cord-006870-f5w6fw6q 932 10 academic academic JJ cord-006870-f5w6fw6q 932 11 tertiary tertiary JJ cord-006870-f5w6fw6q 932 12 care care NN cord-006870-f5w6fw6q 932 13 trauma trauma NN cord-006870-f5w6fw6q 932 14 , , , cord-006870-f5w6fw6q 932 15 stroke stroke NN cord-006870-f5w6fw6q 932 16 and and CC cord-006870-f5w6fw6q 932 17 neurorehabilitation neurorehabilitation NNP cord-006870-f5w6fw6q 932 18 center center NN cord-006870-f5w6fw6q 932 19 . . . cord-006870-f5w6fw6q 933 1 Data datum NNS cord-006870-f5w6fw6q 933 2 was be VBD cord-006870-f5w6fw6q 933 3 collected collect VBN cord-006870-f5w6fw6q 933 4 over over IN cord-006870-f5w6fw6q 933 5 a a DT cord-006870-f5w6fw6q 933 6 year year NN cord-006870-f5w6fw6q 933 7 from from IN cord-006870-f5w6fw6q 933 8 Rapid Rapid NNP cord-006870-f5w6fw6q 933 9 Response Response NNP cord-006870-f5w6fw6q 933 10 System System NNP cord-006870-f5w6fw6q 933 11 activations activation NNS cord-006870-f5w6fw6q 933 12 ( ( -LRB- cord-006870-f5w6fw6q 933 13 RRSa RRSa NNP cord-006870-f5w6fw6q 933 14 ) ) -RRB- cord-006870-f5w6fw6q 933 15 . . . cord-006870-f5w6fw6q 934 1 In in IN cord-006870-f5w6fw6q 934 2 one one CD cord-006870-f5w6fw6q 934 3 year year NN cord-006870-f5w6fw6q 934 4 , , , cord-006870-f5w6fw6q 934 5 our -PRON- PRP$ cord-006870-f5w6fw6q 934 6 center center NN cord-006870-f5w6fw6q 934 7 had have VBD cord-006870-f5w6fw6q 934 8 5388 5388 CD cord-006870-f5w6fw6q 934 9 admissions admission NNS cord-006870-f5w6fw6q 934 10 . . . cord-006870-f5w6fw6q 935 1 169 169 CD cord-006870-f5w6fw6q 935 2 RRSa RRSa NNS cord-006870-f5w6fw6q 935 3 were be VBD cord-006870-f5w6fw6q 935 4 performed perform VBN cord-006870-f5w6fw6q 935 5 on on IN cord-006870-f5w6fw6q 935 6 140 140 CD cord-006870-f5w6fw6q 935 7 patients patient NNS cord-006870-f5w6fw6q 935 8 . . . cord-006870-f5w6fw6q 936 1 Most Most JJS cord-006870-f5w6fw6q 936 2 common common JJ cord-006870-f5w6fw6q 936 3 admission admission NN cord-006870-f5w6fw6q 936 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 936 5 was be VBD cord-006870-f5w6fw6q 936 6 ischemic ischemic JJ cord-006870-f5w6fw6q 936 7 stroke stroke NN cord-006870-f5w6fw6q 936 8 45 45 CD cord-006870-f5w6fw6q 936 9 ( ( -LRB- cord-006870-f5w6fw6q 936 10 32 32 CD cord-006870-f5w6fw6q 936 11 % % NN cord-006870-f5w6fw6q 936 12 ) ) -RRB- cord-006870-f5w6fw6q 936 13 . . . cord-006870-f5w6fw6q 937 1 Most Most JJS cord-006870-f5w6fw6q 937 2 common common JJ cord-006870-f5w6fw6q 937 3 RRSa RRSa NNP cord-006870-f5w6fw6q 937 4 organ organ NN cord-006870-f5w6fw6q 937 5 system system NN cord-006870-f5w6fw6q 937 6 involvement involvement NN cord-006870-f5w6fw6q 937 7 was be VBD cord-006870-f5w6fw6q 937 8 respiratory respiratory JJ cord-006870-f5w6fw6q 937 9 system system NN cord-006870-f5w6fw6q 937 10 ( ( -LRB- cord-006870-f5w6fw6q 937 11 n=59 n=59 FW cord-006870-f5w6fw6q 937 12 , , , cord-006870-f5w6fw6q 937 13 34.8 34.8 CD cord-006870-f5w6fw6q 937 14 % % NN cord-006870-f5w6fw6q 937 15 ) ) -RRB- cord-006870-f5w6fw6q 937 16 . . . cord-006870-f5w6fw6q 938 1 The the DT cord-006870-f5w6fw6q 938 2 only only JJ cord-006870-f5w6fw6q 938 3 predictors predictor NNS cord-006870-f5w6fw6q 938 4 of of IN cord-006870-f5w6fw6q 938 5 death death NN cord-006870-f5w6fw6q 938 6 or or CC cord-006870-f5w6fw6q 938 7 new new JJ cord-006870-f5w6fw6q 938 8 limitation limitation NN cord-006870-f5w6fw6q 938 9 of of IN cord-006870-f5w6fw6q 938 10 care care NN cord-006870-f5w6fw6q 938 11 in in IN cord-006870-f5w6fw6q 938 12 those those DT cord-006870-f5w6fw6q 938 13 patients patient NNS cord-006870-f5w6fw6q 938 14 who who WP cord-006870-f5w6fw6q 938 15 had have VBD cord-006870-f5w6fw6q 938 16 RRSa RRSa NNS cord-006870-f5w6fw6q 938 17 were be VBD cord-006870-f5w6fw6q 938 18 age age NN cord-006870-f5w6fw6q 938 19 ( ( -LRB- cord-006870-f5w6fw6q 938 20 67 67 CD cord-006870-f5w6fw6q 938 21 years year NNS cord-006870-f5w6fw6q 938 22 vs vs IN cord-006870-f5w6fw6q 938 23 58 58 CD cord-006870-f5w6fw6q 938 24 years year NNS cord-006870-f5w6fw6q 938 25 , , , cord-006870-f5w6fw6q 938 26 p p NN cord-006870-f5w6fw6q 938 27 < < XX cord-006870-f5w6fw6q 938 28 0.01 0.01 CD cord-006870-f5w6fw6q 938 29 ) ) -RRB- cord-006870-f5w6fw6q 938 30 and and CC cord-006870-f5w6fw6q 938 31 history history NN cord-006870-f5w6fw6q 938 32 of of IN cord-006870-f5w6fw6q 938 33 cancer cancer NN cord-006870-f5w6fw6q 938 34 8 8 CD cord-006870-f5w6fw6q 938 35 ( ( -LRB- cord-006870-f5w6fw6q 938 36 26 26 CD cord-006870-f5w6fw6q 938 37 % % NN cord-006870-f5w6fw6q 938 38 ) ) -RRB- cord-006870-f5w6fw6q 939 1 vs vs IN cord-006870-f5w6fw6q 939 2 11 11 CD cord-006870-f5w6fw6q 939 3 ( ( -LRB- cord-006870-f5w6fw6q 939 4 19 19 CD cord-006870-f5w6fw6q 939 5 % % NN cord-006870-f5w6fw6q 939 6 ) ) -RRB- cord-006870-f5w6fw6q 939 7 p=0.02 p=0.02 NN cord-006870-f5w6fw6q 939 8 . . . cord-006870-f5w6fw6q 940 1 62.1 62.1 CD cord-006870-f5w6fw6q 940 2 % % NN cord-006870-f5w6fw6q 940 3 ( ( -LRB- cord-006870-f5w6fw6q 940 4 n=105 n=105 NNP cord-006870-f5w6fw6q 940 5 ) ) -RRB- cord-006870-f5w6fw6q 940 6 of of IN cord-006870-f5w6fw6q 940 7 RRSa RRSa NNS cord-006870-f5w6fw6q 940 8 happened happen VBD cord-006870-f5w6fw6q 940 9 during during IN cord-006870-f5w6fw6q 940 10 day day NN cord-006870-f5w6fw6q 940 11 shift shift NN cord-006870-f5w6fw6q 940 12 and and CC cord-006870-f5w6fw6q 940 13 37.9 37.9 CD cord-006870-f5w6fw6q 940 14 % % NN cord-006870-f5w6fw6q 940 15 ( ( -LRB- cord-006870-f5w6fw6q 940 16 n=64 n=64 NNP cord-006870-f5w6fw6q 940 17 ) ) -RRB- cord-006870-f5w6fw6q 940 18 during during IN cord-006870-f5w6fw6q 940 19 night night NN cord-006870-f5w6fw6q 940 20 shift shift NN cord-006870-f5w6fw6q 940 21 . . . cord-006870-f5w6fw6q 941 1 20.7 20.7 CD cord-006870-f5w6fw6q 941 2 % % NN cord-006870-f5w6fw6q 941 3 ( ( -LRB- cord-006870-f5w6fw6q 941 4 n=35 n=35 NNP cord-006870-f5w6fw6q 941 5 ) ) -RRB- cord-006870-f5w6fw6q 941 6 of of IN cord-006870-f5w6fw6q 941 7 RRSa RRSa NNS cord-006870-f5w6fw6q 941 8 happened happen VBD cord-006870-f5w6fw6q 941 9 around around IN cord-006870-f5w6fw6q 941 10 shift shift NN cord-006870-f5w6fw6q 941 11 change change NN cord-006870-f5w6fw6q 941 12 and and CC cord-006870-f5w6fw6q 941 13 were be VBD cord-006870-f5w6fw6q 941 14 more more RBR cord-006870-f5w6fw6q 941 15 likely likely JJ cord-006870-f5w6fw6q 941 16 to to TO cord-006870-f5w6fw6q 941 17 result result VB cord-006870-f5w6fw6q 941 18 in in IN cord-006870-f5w6fw6q 941 19 an an DT cord-006870-f5w6fw6q 941 20 unplanned unplanned JJ cord-006870-f5w6fw6q 941 21 ICU ICU NNP cord-006870-f5w6fw6q 941 22 admission admission NN cord-006870-f5w6fw6q 941 23 . . . cord-006870-f5w6fw6q 942 1 37.7 37.7 CD cord-006870-f5w6fw6q 942 2 % % NN cord-006870-f5w6fw6q 942 3 ( ( -LRB- cord-006870-f5w6fw6q 942 4 n=63 n=63 NNP cord-006870-f5w6fw6q 942 5 ) ) -RRB- cord-006870-f5w6fw6q 942 6 of of IN cord-006870-f5w6fw6q 942 7 RRSa RRSa NNS cord-006870-f5w6fw6q 942 8 happened happen VBD cord-006870-f5w6fw6q 942 9 within within IN cord-006870-f5w6fw6q 942 10 24 24 CD cord-006870-f5w6fw6q 942 11 hours hour NNS cord-006870-f5w6fw6q 942 12 of of IN cord-006870-f5w6fw6q 942 13 admission admission NN cord-006870-f5w6fw6q 942 14 and and CC cord-006870-f5w6fw6q 942 15 were be VBD cord-006870-f5w6fw6q 942 16 more more RBR cord-006870-f5w6fw6q 942 17 likely likely JJ cord-006870-f5w6fw6q 942 18 to to TO cord-006870-f5w6fw6q 942 19 result result VB cord-006870-f5w6fw6q 942 20 in in IN cord-006870-f5w6fw6q 942 21 unplanned unplanned JJ cord-006870-f5w6fw6q 942 22 ICU ICU NNP cord-006870-f5w6fw6q 942 23 admissions admission NNS cord-006870-f5w6fw6q 942 24 . . . cord-006870-f5w6fw6q 943 1 The the DT cord-006870-f5w6fw6q 943 2 most most RBS cord-006870-f5w6fw6q 943 3 common common JJ cord-006870-f5w6fw6q 943 4 reasons reason NNS cord-006870-f5w6fw6q 943 5 for for IN cord-006870-f5w6fw6q 943 6 in in IN cord-006870-f5w6fw6q 943 7 hospital hospital NN cord-006870-f5w6fw6q 943 8 decompensation decompensation NN cord-006870-f5w6fw6q 943 9 in in IN cord-006870-f5w6fw6q 943 10 neurological neurological JJ cord-006870-f5w6fw6q 943 11 inpatients inpatient NNS cord-006870-f5w6fw6q 943 12 are be VBP cord-006870-f5w6fw6q 943 13 nonneurological nonneurological JJ cord-006870-f5w6fw6q 943 14 . . . cord-006870-f5w6fw6q 944 1 Most Most JJS cord-006870-f5w6fw6q 944 2 common common JJ cord-006870-f5w6fw6q 944 3 organ organ NN cord-006870-f5w6fw6q 944 4 system system NN cord-006870-f5w6fw6q 944 5 involvement involvement NN cord-006870-f5w6fw6q 944 6 responsible responsible JJ cord-006870-f5w6fw6q 944 7 for for IN cord-006870-f5w6fw6q 944 8 RRSa RRSa NNS cord-006870-f5w6fw6q 944 9 is be VBZ cord-006870-f5w6fw6q 944 10 respiratory respiratory JJ cord-006870-f5w6fw6q 944 11 system system NN cord-006870-f5w6fw6q 944 12 . . . cord-006870-f5w6fw6q 945 1 The the DT cord-006870-f5w6fw6q 945 2 only only JJ cord-006870-f5w6fw6q 945 3 predictors predictor NNS cord-006870-f5w6fw6q 945 4 of of IN cord-006870-f5w6fw6q 945 5 death death NN cord-006870-f5w6fw6q 945 6 or or CC cord-006870-f5w6fw6q 945 7 new new JJ cord-006870-f5w6fw6q 945 8 limitation limitation NN cord-006870-f5w6fw6q 945 9 of of IN cord-006870-f5w6fw6q 945 10 care care NN cord-006870-f5w6fw6q 945 11 were be VBD cord-006870-f5w6fw6q 945 12 history history NN cord-006870-f5w6fw6q 945 13 of of IN cord-006870-f5w6fw6q 945 14 cancer cancer NN cord-006870-f5w6fw6q 945 15 and and CC cord-006870-f5w6fw6q 945 16 age age NN cord-006870-f5w6fw6q 945 17 67 67 CD cord-006870-f5w6fw6q 945 18 and and CC cord-006870-f5w6fw6q 945 19 older old JJR cord-006870-f5w6fw6q 945 20 . . . cord-006870-f5w6fw6q 946 1 RRSa RRSa NNP cord-006870-f5w6fw6q 946 2 activations activation NNS cord-006870-f5w6fw6q 946 3 were be VBD cord-006870-f5w6fw6q 946 4 more more RBR cord-006870-f5w6fw6q 946 5 frequent frequent JJ cord-006870-f5w6fw6q 946 6 during during IN cord-006870-f5w6fw6q 946 7 day day NN cord-006870-f5w6fw6q 946 8 shift shift NN cord-006870-f5w6fw6q 946 9 . . . cord-006870-f5w6fw6q 947 1 However however RB cord-006870-f5w6fw6q 947 2 , , , cord-006870-f5w6fw6q 947 3 there there EX cord-006870-f5w6fw6q 947 4 was be VBD cord-006870-f5w6fw6q 947 5 no no RB cord-006870-f5w6fw6q 947 6 different different JJ cord-006870-f5w6fw6q 947 7 in in IN cord-006870-f5w6fw6q 947 8 the the DT cord-006870-f5w6fw6q 947 9 outcomes outcome NNS cord-006870-f5w6fw6q 947 10 we -PRON- PRP cord-006870-f5w6fw6q 947 11 evaluated evaluate VBD cord-006870-f5w6fw6q 947 12 between between IN cord-006870-f5w6fw6q 947 13 day day NN cord-006870-f5w6fw6q 947 14 and and CC cord-006870-f5w6fw6q 947 15 night night NN cord-006870-f5w6fw6q 947 16 shifts shift NNS cord-006870-f5w6fw6q 947 17 . . . cord-006870-f5w6fw6q 948 1 RRSa RRSa NNS cord-006870-f5w6fw6q 948 2 happening happen VBG cord-006870-f5w6fw6q 948 3 around around IN cord-006870-f5w6fw6q 948 4 shift shift NN cord-006870-f5w6fw6q 948 5 change change NN cord-006870-f5w6fw6q 948 6 wew wew NNP cord-006870-f5w6fw6q 948 7 more more RBR cord-006870-f5w6fw6q 948 8 likely likely JJ cord-006870-f5w6fw6q 948 9 to to TO cord-006870-f5w6fw6q 948 10 result result VB cord-006870-f5w6fw6q 948 11 in in IN cord-006870-f5w6fw6q 948 12 unplanned unplanned JJ cord-006870-f5w6fw6q 948 13 ICU ICU NNP cord-006870-f5w6fw6q 948 14 admission admission NN cord-006870-f5w6fw6q 948 15 . . . cord-006870-f5w6fw6q 949 1 RRSa RRSa NNS cord-006870-f5w6fw6q 949 2 within within IN cord-006870-f5w6fw6q 949 3 24 24 CD cord-006870-f5w6fw6q 949 4 hours hour NNS cord-006870-f5w6fw6q 949 5 of of IN cord-006870-f5w6fw6q 949 6 admission admission NN cord-006870-f5w6fw6q 949 7 showed show VBD cord-006870-f5w6fw6q 949 8 an an DT cord-006870-f5w6fw6q 949 9 increased increase VBN cord-006870-f5w6fw6q 949 10 risk risk NN cord-006870-f5w6fw6q 949 11 of of IN cord-006870-f5w6fw6q 949 12 unplanned unplanned JJ cord-006870-f5w6fw6q 949 13 ICU ICU NNP cord-006870-f5w6fw6q 949 14 admission admission NN cord-006870-f5w6fw6q 949 15 when when WRB cord-006870-f5w6fw6q 949 16 compared compare VBN cord-006870-f5w6fw6q 949 17 to to IN cord-006870-f5w6fw6q 949 18 RRSa RRSa NNS cord-006870-f5w6fw6q 949 19 happening happen VBG cord-006870-f5w6fw6q 949 20 after after IN cord-006870-f5w6fw6q 949 21 24 24 CD cord-006870-f5w6fw6q 949 22 hours hour NNS cord-006870-f5w6fw6q 949 23 of of IN cord-006870-f5w6fw6q 949 24 admission admission NN cord-006870-f5w6fw6q 949 25 . . . cord-006870-f5w6fw6q 950 1 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 950 2 care care NN cord-006870-f5w6fw6q 950 3 is be VBZ cord-006870-f5w6fw6q 950 4 a a DT cord-006870-f5w6fw6q 950 5 growing grow VBG cord-006870-f5w6fw6q 950 6 field field NN cord-006870-f5w6fw6q 950 7 with with IN cord-006870-f5w6fw6q 950 8 an an DT cord-006870-f5w6fw6q 950 9 increasing increase VBG cord-006870-f5w6fw6q 950 10 number number NN cord-006870-f5w6fw6q 950 11 of of IN cord-006870-f5w6fw6q 950 12 dedicated dedicated JJ cord-006870-f5w6fw6q 950 13 neuroscience neuroscience NN cord-006870-f5w6fw6q 950 14 intensive intensive JJ cord-006870-f5w6fw6q 950 15 care care NN cord-006870-f5w6fw6q 950 16 units unit NNS cord-006870-f5w6fw6q 950 17 . . . cord-006870-f5w6fw6q 951 1 In in IN cord-006870-f5w6fw6q 951 2 this this DT cord-006870-f5w6fw6q 951 3 dynamic dynamic JJ cord-006870-f5w6fw6q 951 4 context context NN cord-006870-f5w6fw6q 951 5 , , , cord-006870-f5w6fw6q 951 6 it -PRON- PRP cord-006870-f5w6fw6q 951 7 is be VBZ cord-006870-f5w6fw6q 951 8 unclear unclear JJ cord-006870-f5w6fw6q 951 9 which which WDT cord-006870-f5w6fw6q 951 10 types type NNS cord-006870-f5w6fw6q 951 11 of of IN cord-006870-f5w6fw6q 951 12 physicians physician NNS cord-006870-f5w6fw6q 951 13 provide provide VBP cord-006870-f5w6fw6q 951 14 neurocritical neurocritical JJ cord-006870-f5w6fw6q 951 15 care care NN cord-006870-f5w6fw6q 951 16 across across IN cord-006870-f5w6fw6q 951 17 the the DT cord-006870-f5w6fw6q 951 18 United United NNP cord-006870-f5w6fw6q 951 19 States States NNP cord-006870-f5w6fw6q 951 20 . . . cord-006870-f5w6fw6q 952 1 We -PRON- PRP cord-006870-f5w6fw6q 952 2 performed perform VBD cord-006870-f5w6fw6q 952 3 a a DT cord-006870-f5w6fw6q 952 4 retrospective retrospective JJ cord-006870-f5w6fw6q 952 5 cohort cohort NN cord-006870-f5w6fw6q 952 6 study study NN cord-006870-f5w6fw6q 952 7 using use VBG cord-006870-f5w6fw6q 952 8 claims claim NNS cord-006870-f5w6fw6q 952 9 data datum NNS cord-006870-f5w6fw6q 952 10 from from IN cord-006870-f5w6fw6q 952 11 a a DT cord-006870-f5w6fw6q 952 12 nationally nationally RB cord-006870-f5w6fw6q 952 13 representative representative JJ cord-006870-f5w6fw6q 952 14 5 5 CD cord-006870-f5w6fw6q 952 15 % % NN cord-006870-f5w6fw6q 952 16 within within IN cord-006870-f5w6fw6q 952 17 analyzed analyze VBN cord-006870-f5w6fw6q 952 18 critical critical JJ cord-006870-f5w6fw6q 952 19 care care NN cord-006870-f5w6fw6q 952 20 procedures procedure NNS cord-006870-f5w6fw6q 952 21 . . . cord-006870-f5w6fw6q 953 1 The the DT cord-006870-f5w6fw6q 953 2 primary primary JJ cord-006870-f5w6fw6q 953 3 outcome outcome NN cord-006870-f5w6fw6q 953 4 was be VBD cord-006870-f5w6fw6q 953 5 physician physician NN cord-006870-f5w6fw6q 953 6 specialty specialty NN cord-006870-f5w6fw6q 953 7 , , , cord-006870-f5w6fw6q 953 8 defined define VBN cord-006870-f5w6fw6q 953 9 by by IN cord-006870-f5w6fw6q 953 10 Medicare Medicare NNP cord-006870-f5w6fw6q 953 11 provider provider NN cord-006870-f5w6fw6q 953 12 specialty specialty NN cord-006870-f5w6fw6q 953 13 codes code NNS cord-006870-f5w6fw6q 953 14 . . . cord-006870-f5w6fw6q 954 1 In in IN cord-006870-f5w6fw6q 954 2 a a DT cord-006870-f5w6fw6q 954 3 sensitivity sensitivity NN cord-006870-f5w6fw6q 954 4 analysis analysis NN cord-006870-f5w6fw6q 954 5 , , , cord-006870-f5w6fw6q 954 6 we -PRON- PRP cord-006870-f5w6fw6q 954 7 excluded exclude VBD cord-006870-f5w6fw6q 954 8 claims claim NNS cord-006870-f5w6fw6q 954 9 for for IN cord-006870-f5w6fw6q 954 10 services service NNS cord-006870-f5w6fw6q 954 11 on on IN cord-006870-f5w6fw6q 954 12 the the DT cord-006870-f5w6fw6q 954 13 day day NN cord-006870-f5w6fw6q 954 14 of of IN cord-006870-f5w6fw6q 954 15 admission admission NN cord-006870-f5w6fw6q 954 16 and and CC cord-006870-f5w6fw6q 954 17 claims claim NNS cord-006870-f5w6fw6q 954 18 associated associate VBN cord-006870-f5w6fw6q 954 19 with with IN cord-006870-f5w6fw6q 954 20 a a DT cord-006870-f5w6fw6q 954 21 diagnosis diagnosis NN cord-006870-f5w6fw6q 954 22 of of IN cord-006870-f5w6fw6q 954 23 cardiac cardiac JJ cord-006870-f5w6fw6q 954 24 arrest arrest NN cord-006870-f5w6fw6q 954 25 , , , cord-006870-f5w6fw6q 954 26 since since IN cord-006870-f5w6fw6q 954 27 these these DT cord-006870-f5w6fw6q 954 28 activities activity NNS cord-006870-f5w6fw6q 954 29 may may MD cord-006870-f5w6fw6q 954 30 often often RB cord-006870-f5w6fw6q 954 31 occur occur VB cord-006870-f5w6fw6q 954 32 outside outside RB cord-006870-f5w6fw6q 954 33 of of IN cord-006870-f5w6fw6q 954 34 neuroscience neuroscience NN cord-006870-f5w6fw6q 954 35 intensive intensive JJ cord-006870-f5w6fw6q 954 36 care care NN cord-006870-f5w6fw6q 954 37 units unit NNS cord-006870-f5w6fw6q 954 38 . . . cord-006870-f5w6fw6q 955 1 We -PRON- PRP cord-006870-f5w6fw6q 955 2 identified identify VBD cord-006870-f5w6fw6q 955 3 _SP cord-006870-f5w6fw6q 955 4 Between between IN cord-006870-f5w6fw6q 955 5 2009 2009 CD cord-006870-f5w6fw6q 955 6 and and CC cord-006870-f5w6fw6q 955 7 2014 2014 CD cord-006870-f5w6fw6q 955 8 , , , cord-006870-f5w6fw6q 955 9 neurologists neurologist NNS cord-006870-f5w6fw6q 955 10 were be VBD cord-006870-f5w6fw6q 955 11 responsible responsible JJ cord-006870-f5w6fw6q 955 12 for for IN cord-006870-f5w6fw6q 955 13 approximately approximately RB cord-006870-f5w6fw6q 955 14 one one CD cord-006870-f5w6fw6q 955 15 - - HYPH cord-006870-f5w6fw6q 955 16 quarter quarter NN cord-006870-f5w6fw6q 955 17 of of IN cord-006870-f5w6fw6q 955 18 neurocritical neurocritical NNP cord-006870-f5w6fw6q 955 19 care care NN cord-006870-f5w6fw6q 955 20 services service NNS cord-006870-f5w6fw6q 955 21 among among IN cord-006870-f5w6fw6q 955 22 a a DT cord-006870-f5w6fw6q 955 23 nationally nationally RB cord-006870-f5w6fw6q 955 24 representative representative JJ cord-006870-f5w6fw6q 955 25 cohort cohort NN cord-006870-f5w6fw6q 955 26 of of IN cord-006870-f5w6fw6q 955 27 elderly elderly JJ cord-006870-f5w6fw6q 955 28 patients patient NNS cord-006870-f5w6fw6q 955 29 . . . cord-006870-f5w6fw6q 956 1 Critically critically RB cord-006870-f5w6fw6q 956 2 - - HYPH cord-006870-f5w6fw6q 956 3 ill ill JJ cord-006870-f5w6fw6q 956 4 patients patient NNS cord-006870-f5w6fw6q 956 5 on on IN cord-006870-f5w6fw6q 956 6 mechanical mechanical JJ cord-006870-f5w6fw6q 956 7 ventilation ventilation NN cord-006870-f5w6fw6q 956 8 ( ( -LRB- cord-006870-f5w6fw6q 956 9 MV MV NNP cord-006870-f5w6fw6q 956 10 ) ) -RRB- cord-006870-f5w6fw6q 956 11 can can MD cord-006870-f5w6fw6q 956 12 not not RB cord-006870-f5w6fw6q 956 13 verbally verbally RB cord-006870-f5w6fw6q 956 14 communicate communicate VB cord-006870-f5w6fw6q 956 15 . . . cord-006870-f5w6fw6q 957 1 Research research NN cord-006870-f5w6fw6q 957 2 suggests suggest VBZ cord-006870-f5w6fw6q 957 3 several several JJ cord-006870-f5w6fw6q 957 4 phenomena phenomenon NNS cord-006870-f5w6fw6q 957 5 occur occur VBP cord-006870-f5w6fw6q 957 6 in in IN cord-006870-f5w6fw6q 957 7 patients patient NNS cord-006870-f5w6fw6q 957 8 during during IN cord-006870-f5w6fw6q 957 9 MV MV NNP cord-006870-f5w6fw6q 957 10 because because IN cord-006870-f5w6fw6q 957 11 of of IN cord-006870-f5w6fw6q 957 12 impaired impaired JJ cord-006870-f5w6fw6q 957 13 communication communication NN cord-006870-f5w6fw6q 957 14 including include VBG cord-006870-f5w6fw6q 957 15 anxiety anxiety NN cord-006870-f5w6fw6q 957 16 , , , cord-006870-f5w6fw6q 957 17 loss loss NN cord-006870-f5w6fw6q 957 18 of of IN cord-006870-f5w6fw6q 957 19 control control NN cord-006870-f5w6fw6q 957 20 , , , cord-006870-f5w6fw6q 957 21 loneliness loneliness NN cord-006870-f5w6fw6q 957 22 , , , cord-006870-f5w6fw6q 957 23 and and CC cord-006870-f5w6fw6q 957 24 compromised compromised JJ cord-006870-f5w6fw6q 957 25 interaction interaction NN cord-006870-f5w6fw6q 957 26 ( ( -LRB- cord-006870-f5w6fw6q 957 27 Schou Schou NNP cord-006870-f5w6fw6q 957 28 and and CC cord-006870-f5w6fw6q 957 29 Egerod Egerod NNP cord-006870-f5w6fw6q 957 30 , , , cord-006870-f5w6fw6q 957 31 2008 2008 CD cord-006870-f5w6fw6q 957 32 ) ) -RRB- cord-006870-f5w6fw6q 957 33 . . . cord-006870-f5w6fw6q 958 1 For for IN cord-006870-f5w6fw6q 958 2 neurocritical neurocritical JJ cord-006870-f5w6fw6q 958 3 care care NN cord-006870-f5w6fw6q 958 4 patients patient NNS cord-006870-f5w6fw6q 958 5 , , , cord-006870-f5w6fw6q 958 6 this this DT cord-006870-f5w6fw6q 958 7 can can MD cord-006870-f5w6fw6q 958 8 be be VB cord-006870-f5w6fw6q 958 9 especially especially RB cord-006870-f5w6fw6q 958 10 profound profound JJ cord-006870-f5w6fw6q 958 11 when when WRB cord-006870-f5w6fw6q 958 12 coupled couple VBN cord-006870-f5w6fw6q 958 13 with with IN cord-006870-f5w6fw6q 958 14 cognitive cognitive JJ cord-006870-f5w6fw6q 958 15 and and CC cord-006870-f5w6fw6q 958 16 motor motor NN cord-006870-f5w6fw6q 958 17 / / SYM cord-006870-f5w6fw6q 958 18 sensory sensory JJ cord-006870-f5w6fw6q 958 19 deficits deficit NNS cord-006870-f5w6fw6q 958 20 . . . cord-006870-f5w6fw6q 959 1 Currently currently RB cord-006870-f5w6fw6q 959 2 , , , cord-006870-f5w6fw6q 959 3 the the DT cord-006870-f5w6fw6q 959 4 BLOM BLOM NNP cord-006870-f5w6fw6q 959 5 ® ® POS cord-006870-f5w6fw6q 959 6 speaking speak VBG cord-006870-f5w6fw6q 959 7 valve valve NN cord-006870-f5w6fw6q 959 8 ( ( -LRB- cord-006870-f5w6fw6q 959 9 SV SV NNP cord-006870-f5w6fw6q 959 10 ) ) -RRB- cord-006870-f5w6fw6q 959 11 is be VBZ cord-006870-f5w6fw6q 959 12 the the DT cord-006870-f5w6fw6q 959 13 only only JJ cord-006870-f5w6fw6q 959 14 approved approve VBN cord-006870-f5w6fw6q 959 15 product product NN cord-006870-f5w6fw6q 959 16 available available JJ cord-006870-f5w6fw6q 959 17 that that WDT cord-006870-f5w6fw6q 959 18 allows allow VBZ cord-006870-f5w6fw6q 959 19 phonation phonation NN cord-006870-f5w6fw6q 959 20 in in IN cord-006870-f5w6fw6q 959 21 ventilator ventilator NN cord-006870-f5w6fw6q 959 22 - - HYPH cord-006870-f5w6fw6q 959 23 dependent dependent JJ cord-006870-f5w6fw6q 959 24 patients patient NNS cord-006870-f5w6fw6q 959 25 with with IN cord-006870-f5w6fw6q 959 26 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 959 27 . . . cord-006870-f5w6fw6q 960 1 SV SV NNP cord-006870-f5w6fw6q 960 2 trials trial NNS cord-006870-f5w6fw6q 960 3 are be VBP cord-006870-f5w6fw6q 960 4 known know VBN cord-006870-f5w6fw6q 960 5 to to TO cord-006870-f5w6fw6q 960 6 facilitate facilitate VB cord-006870-f5w6fw6q 960 7 vent vent NN cord-006870-f5w6fw6q 960 8 - - HYPH cord-006870-f5w6fw6q 960 9 weaning weaning NN cord-006870-f5w6fw6q 960 10 . . . cord-006870-f5w6fw6q 961 1 The the DT cord-006870-f5w6fw6q 961 2 current current JJ cord-006870-f5w6fw6q 961 3 standard standard NN cord-006870-f5w6fw6q 961 4 of of IN cord-006870-f5w6fw6q 961 5 care care NN cord-006870-f5w6fw6q 961 6 ( ( -LRB- cord-006870-f5w6fw6q 961 7 Passy Passy NNP cord-006870-f5w6fw6q 961 8 - - HYPH cord-006870-f5w6fw6q 961 9 Muir Muir NNP cord-006870-f5w6fw6q 961 10 speaking speak VBG cord-006870-f5w6fw6q 961 11 valve valve NN cord-006870-f5w6fw6q 961 12 , , , cord-006870-f5w6fw6q 961 13 30 30 CD cord-006870-f5w6fw6q 961 14 minute minute NN cord-006870-f5w6fw6q 961 15 trials trial NNS cord-006870-f5w6fw6q 961 16 ) ) -RRB- cord-006870-f5w6fw6q 961 17 , , , cord-006870-f5w6fw6q 961 18 is be VBZ cord-006870-f5w6fw6q 961 19 contra contra NNP cord-006870-f5w6fw6q 961 20 - - : cord-006870-f5w6fw6q 961 21 indicated indicate VBN cord-006870-f5w6fw6q 961 22 in in IN cord-006870-f5w6fw6q 961 23 patients patient NNS cord-006870-f5w6fw6q 961 24 who who WP cord-006870-f5w6fw6q 961 25 can can MD cord-006870-f5w6fw6q 961 26 not not RB cord-006870-f5w6fw6q 961 27 tolerate tolerate VB cord-006870-f5w6fw6q 961 28 cuff cuff NN cord-006870-f5w6fw6q 961 29 deflation deflation NN cord-006870-f5w6fw6q 961 30 . . . cord-006870-f5w6fw6q 962 1 As as IN cord-006870-f5w6fw6q 962 2 such such JJ cord-006870-f5w6fw6q 962 3 , , , cord-006870-f5w6fw6q 962 4 the the DT cord-006870-f5w6fw6q 962 5 BLOM BLOM NNP cord-006870-f5w6fw6q 962 6 ® ® HYPH cord-006870-f5w6fw6q 962 7 SV SV NNP cord-006870-f5w6fw6q 962 8 was be VBD cord-006870-f5w6fw6q 962 9 evaluated evaluate VBN cord-006870-f5w6fw6q 962 10 for for IN cord-006870-f5w6fw6q 962 11 clinical clinical JJ cord-006870-f5w6fw6q 962 12 and and CC cord-006870-f5w6fw6q 962 13 quality quality JJ cord-006870-f5w6fw6q 962 14 efficacy efficacy NN cord-006870-f5w6fw6q 962 15 . . . cord-006870-f5w6fw6q 963 1 We -PRON- PRP cord-006870-f5w6fw6q 963 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 963 3 evaluated evaluate VBD cord-006870-f5w6fw6q 963 4 clinical clinical JJ cord-006870-f5w6fw6q 963 5 outcomes outcome NNS cord-006870-f5w6fw6q 963 6 associated associate VBN cord-006870-f5w6fw6q 963 7 with with IN cord-006870-f5w6fw6q 963 8 BLOM BLOM NNP cord-006870-f5w6fw6q 963 9 ® ® POS cord-006870-f5w6fw6q 963 10 SV SV NNP cord-006870-f5w6fw6q 963 11 on on IN cord-006870-f5w6fw6q 963 12 MV MV NNP cord-006870-f5w6fw6q 963 13 during during IN cord-006870-f5w6fw6q 963 14 a a DT cord-006870-f5w6fw6q 963 15 trial trial NN cord-006870-f5w6fw6q 963 16 in in IN cord-006870-f5w6fw6q 963 17 a a DT cord-006870-f5w6fw6q 963 18 neuroICU neuroicu NN cord-006870-f5w6fw6q 963 19 of of IN cord-006870-f5w6fw6q 963 20 a a DT cord-006870-f5w6fw6q 963 21 large large JJ cord-006870-f5w6fw6q 963 22 tertiary tertiary JJ cord-006870-f5w6fw6q 963 23 center center NN cord-006870-f5w6fw6q 963 24 between between IN cord-006870-f5w6fw6q 963 25 6/1/2014 6/1/2014 CD cord-006870-f5w6fw6q 963 26 and and CC cord-006870-f5w6fw6q 963 27 5/31/2016 5/31/2016 CD cord-006870-f5w6fw6q 963 28 . . . cord-006870-f5w6fw6q 964 1 Baseline baseline JJ cord-006870-f5w6fw6q 964 2 demographics demographic NNS cord-006870-f5w6fw6q 964 3 , , , cord-006870-f5w6fw6q 964 4 diagnoses diagnosis NNS cord-006870-f5w6fw6q 964 5 , , , cord-006870-f5w6fw6q 964 6 physiologic physiologic JJ cord-006870-f5w6fw6q 964 7 , , , cord-006870-f5w6fw6q 964 8 sedation sedation NN cord-006870-f5w6fw6q 964 9 , , , cord-006870-f5w6fw6q 964 10 delirium delirium NN cord-006870-f5w6fw6q 964 11 , , , cord-006870-f5w6fw6q 964 12 mobility mobility NN cord-006870-f5w6fw6q 964 13 and and CC cord-006870-f5w6fw6q 964 14 swallowing swallowing NN cord-006870-f5w6fw6q 964 15 parameters parameter NNS cord-006870-f5w6fw6q 964 16 , , , cord-006870-f5w6fw6q 964 17 length length NN cord-006870-f5w6fw6q 964 18 of of IN cord-006870-f5w6fw6q 964 19 stay stay NN cord-006870-f5w6fw6q 964 20 , , , cord-006870-f5w6fw6q 964 21 ventilator ventilator NN cord-006870-f5w6fw6q 964 22 modes mode NNS cord-006870-f5w6fw6q 964 23 and and CC cord-006870-f5w6fw6q 964 24 settings setting NNS cord-006870-f5w6fw6q 964 25 , , , cord-006870-f5w6fw6q 964 26 ventilator ventilator NN cord-006870-f5w6fw6q 964 27 days day NNS cord-006870-f5w6fw6q 964 28 , , , cord-006870-f5w6fw6q 964 29 work work NN cord-006870-f5w6fw6q 964 30 of of IN cord-006870-f5w6fw6q 964 31 breathing breathing NN cord-006870-f5w6fw6q 964 32 and and CC cord-006870-f5w6fw6q 964 33 presence presence NN cord-006870-f5w6fw6q 964 34 of of IN cord-006870-f5w6fw6q 964 35 pneumonia pneumonia NN cord-006870-f5w6fw6q 964 36 were be VBD cord-006870-f5w6fw6q 964 37 abstracted abstract VBN cord-006870-f5w6fw6q 964 38 along along IN cord-006870-f5w6fw6q 964 39 with with IN cord-006870-f5w6fw6q 964 40 patient patient NN cord-006870-f5w6fw6q 964 41 , , , cord-006870-f5w6fw6q 964 42 family family NN cord-006870-f5w6fw6q 964 43 and and CC cord-006870-f5w6fw6q 964 44 interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 964 45 staff staff NN cord-006870-f5w6fw6q 964 46 satisfaction satisfaction NN cord-006870-f5w6fw6q 964 47 survey survey NN cord-006870-f5w6fw6q 964 48 results result NNS cord-006870-f5w6fw6q 964 49 . . . cord-006870-f5w6fw6q 965 1 28 28 CD cord-006870-f5w6fw6q 965 2 patients patient NNS cord-006870-f5w6fw6q 965 3 were be VBD cord-006870-f5w6fw6q 965 4 recommended recommend VBN cord-006870-f5w6fw6q 965 5 for for IN cord-006870-f5w6fw6q 965 6 BLOM BLOM NNP cord-006870-f5w6fw6q 966 1 ® ® VB cord-006870-f5w6fw6q 966 2 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 966 3 . . . cord-006870-f5w6fw6q 967 1 22 22 CD cord-006870-f5w6fw6q 967 2 patients patient NNS cord-006870-f5w6fw6q 967 3 received receive VBD cord-006870-f5w6fw6q 967 4 SV sv NN cord-006870-f5w6fw6q 967 5 trials trial NNS cord-006870-f5w6fw6q 967 6 . . . cord-006870-f5w6fw6q 968 1 Of of IN cord-006870-f5w6fw6q 968 2 the the DT cord-006870-f5w6fw6q 968 3 185 185 CD cord-006870-f5w6fw6q 968 4 trials trial NNS cord-006870-f5w6fw6q 968 5 were be VBD cord-006870-f5w6fw6q 968 6 performed perform VBN cord-006870-f5w6fw6q 968 7 , , , cord-006870-f5w6fw6q 968 8 28 28 CD cord-006870-f5w6fw6q 968 9 % % NN cord-006870-f5w6fw6q 968 10 ( ( -LRB- cord-006870-f5w6fw6q 968 11 52 52 CD cord-006870-f5w6fw6q 968 12 ) ) -RRB- cord-006870-f5w6fw6q 968 13 were be VBD cord-006870-f5w6fw6q 968 14 optimal optimal JJ cord-006870-f5w6fw6q 968 15 / / SYM cord-006870-f5w6fw6q 968 16 completed complete VBN cord-006870-f5w6fw6q 968 17 ( ( -LRB- cord-006870-f5w6fw6q 968 18 30 30 CD cord-006870-f5w6fw6q 968 19 + + SYM cord-006870-f5w6fw6q 968 20 minutes minute NNS cord-006870-f5w6fw6q 968 21 ) ) -RRB- cord-006870-f5w6fw6q 968 22 ; ; : cord-006870-f5w6fw6q 968 23 36 36 CD cord-006870-f5w6fw6q 968 24 % % NN cord-006870-f5w6fw6q 968 25 ( ( -LRB- cord-006870-f5w6fw6q 968 26 68 68 CD cord-006870-f5w6fw6q 968 27 ) ) -RRB- cord-006870-f5w6fw6q 968 28 were be VBD cord-006870-f5w6fw6q 968 29 suboptimal suboptimal JJ cord-006870-f5w6fw6q 968 30 / / SYM cord-006870-f5w6fw6q 968 31 completed complete VBN cord-006870-f5w6fw6q 968 32 trials trial NNS cord-006870-f5w6fw6q 968 33 ( ( -LRB- cord-006870-f5w6fw6q 968 34 0 0 CD cord-006870-f5w6fw6q 968 35 - - SYM cord-006870-f5w6fw6q 968 36 29 29 CD cord-006870-f5w6fw6q 968 37 minutes minute NNS cord-006870-f5w6fw6q 968 38 ) ) -RRB- cord-006870-f5w6fw6q 968 39 ; ; : cord-006870-f5w6fw6q 968 40 14 14 CD cord-006870-f5w6fw6q 968 41 % % NN cord-006870-f5w6fw6q 968 42 ( ( -LRB- cord-006870-f5w6fw6q 968 43 27 27 CD cord-006870-f5w6fw6q 968 44 ) ) -RRB- cord-006870-f5w6fw6q 968 45 unable unable JJ cord-006870-f5w6fw6q 968 46 to to TO cord-006870-f5w6fw6q 968 47 complete complete VB cord-006870-f5w6fw6q 968 48 . . . cord-006870-f5w6fw6q 969 1 Satisfaction satisfaction NN cord-006870-f5w6fw6q 969 2 results result NNS cord-006870-f5w6fw6q 969 3 from from IN cord-006870-f5w6fw6q 969 4 patients patient NNS cord-006870-f5w6fw6q 969 5 / / SYM cord-006870-f5w6fw6q 969 6 families family NNS cord-006870-f5w6fw6q 969 7 were be VBD cord-006870-f5w6fw6q 969 8 positive positive JJ cord-006870-f5w6fw6q 969 9 compared compare VBN cord-006870-f5w6fw6q 969 10 to to IN cord-006870-f5w6fw6q 969 11 the the DT cord-006870-f5w6fw6q 969 12 interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 969 13 team team NN cord-006870-f5w6fw6q 969 14 survey survey NN cord-006870-f5w6fw6q 969 15 results result NNS cord-006870-f5w6fw6q 969 16 . . . cord-006870-f5w6fw6q 970 1 Remaining remain VBG cord-006870-f5w6fw6q 970 2 parameters parameter NNS cord-006870-f5w6fw6q 970 3 currently currently RB cord-006870-f5w6fw6q 970 4 in in IN cord-006870-f5w6fw6q 970 5 analysis analysis NN cord-006870-f5w6fw6q 970 6 with with IN cord-006870-f5w6fw6q 970 7 results result NNS cord-006870-f5w6fw6q 970 8 pending pende VBG cord-006870-f5w6fw6q 970 9 , , , cord-006870-f5w6fw6q 970 10 to to TO cord-006870-f5w6fw6q 970 11 be be VB cord-006870-f5w6fw6q 970 12 completed complete VBN cord-006870-f5w6fw6q 970 13 by by IN cord-006870-f5w6fw6q 970 14 end end NN cord-006870-f5w6fw6q 970 15 of of IN cord-006870-f5w6fw6q 970 16 August August NNP cord-006870-f5w6fw6q 970 17 , , , cord-006870-f5w6fw6q 970 18 2017 2017 CD cord-006870-f5w6fw6q 970 19 . . . cord-006870-f5w6fw6q 971 1 Impaired impaired JJ cord-006870-f5w6fw6q 971 2 communication communication NN cord-006870-f5w6fw6q 971 3 during during IN cord-006870-f5w6fw6q 971 4 MV MV NNP cord-006870-f5w6fw6q 971 5 is be VBZ cord-006870-f5w6fw6q 971 6 suboptimal suboptimal JJ cord-006870-f5w6fw6q 971 7 for for IN cord-006870-f5w6fw6q 971 8 neurocritical neurocritical JJ cord-006870-f5w6fw6q 971 9 care care NN cord-006870-f5w6fw6q 971 10 patients patient NNS cord-006870-f5w6fw6q 971 11 . . . cord-006870-f5w6fw6q 972 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 972 2 clinical clinical JJ cord-006870-f5w6fw6q 972 3 experiences experience NNS cord-006870-f5w6fw6q 972 4 with with IN cord-006870-f5w6fw6q 972 5 BLOM BLOM NNP cord-006870-f5w6fw6q 972 6 ® ® POS cord-006870-f5w6fw6q 972 7 SV SV NNP cord-006870-f5w6fw6q 972 8 showed show VBD cord-006870-f5w6fw6q 972 9 positive positive JJ cord-006870-f5w6fw6q 972 10 and and CC cord-006870-f5w6fw6q 972 11 negative negative JJ cord-006870-f5w6fw6q 972 12 outcomes outcome NNS cord-006870-f5w6fw6q 972 13 . . . cord-006870-f5w6fw6q 973 1 Positive positive JJ cord-006870-f5w6fw6q 973 2 benefits benefit NNS cord-006870-f5w6fw6q 973 3 were be VBD cord-006870-f5w6fw6q 973 4 enhanced enhance VBN cord-006870-f5w6fw6q 973 5 patient patient NN cord-006870-f5w6fw6q 973 6 / / SYM cord-006870-f5w6fw6q 973 7 family family NN cord-006870-f5w6fw6q 973 8 engagement engagement NN cord-006870-f5w6fw6q 973 9 and and CC cord-006870-f5w6fw6q 973 10 family family NN cord-006870-f5w6fw6q 973 11 satisfaction satisfaction NN cord-006870-f5w6fw6q 973 12 . . . cord-006870-f5w6fw6q 974 1 Unanticipated unanticipated JJ cord-006870-f5w6fw6q 974 2 obstacles obstacle NNS cord-006870-f5w6fw6q 974 3 included include VBD cord-006870-f5w6fw6q 974 4 significant significant JJ cord-006870-f5w6fw6q 974 5 increase increase NN cord-006870-f5w6fw6q 974 6 in in IN cord-006870-f5w6fw6q 974 7 patient patient JJ cord-006870-f5w6fw6q 974 8 fatigue fatigue NN cord-006870-f5w6fw6q 974 9 during during IN cord-006870-f5w6fw6q 974 10 SV SV NNP cord-006870-f5w6fw6q 974 11 trials trial NNS cord-006870-f5w6fw6q 974 12 , , , cord-006870-f5w6fw6q 974 13 often often RB cord-006870-f5w6fw6q 974 14 delaying delay VBG cord-006870-f5w6fw6q 974 15 ventilator ventilator NN cord-006870-f5w6fw6q 974 16 weaning wean VBG cord-006870-f5w6fw6q 974 17 . . . cord-006870-f5w6fw6q 975 1 Further further JJ cord-006870-f5w6fw6q 975 2 study study NN cord-006870-f5w6fw6q 975 3 is be VBZ cord-006870-f5w6fw6q 975 4 needed need VBN cord-006870-f5w6fw6q 975 5 to to TO cord-006870-f5w6fw6q 975 6 determine determine VB cord-006870-f5w6fw6q 975 7 efficacy efficacy NN cord-006870-f5w6fw6q 975 8 in in IN cord-006870-f5w6fw6q 975 9 this this DT cord-006870-f5w6fw6q 975 10 population population NN cord-006870-f5w6fw6q 975 11 . . . cord-006870-f5w6fw6q 976 1 Patients patient NNS cord-006870-f5w6fw6q 976 2 with with IN cord-006870-f5w6fw6q 976 3 clinical clinical JJ cord-006870-f5w6fw6q 976 4 signs sign NNS cord-006870-f5w6fw6q 976 5 of of IN cord-006870-f5w6fw6q 976 6 cerebral cerebral JJ cord-006870-f5w6fw6q 976 7 herniation herniation NN cord-006870-f5w6fw6q 976 8 require require VBP cord-006870-f5w6fw6q 976 9 immediate immediate JJ cord-006870-f5w6fw6q 976 10 intervention intervention NN cord-006870-f5w6fw6q 976 11 known know VBN cord-006870-f5w6fw6q 976 12 as as IN cord-006870-f5w6fw6q 976 13 a a DT cord-006870-f5w6fw6q 976 14 " " `` cord-006870-f5w6fw6q 976 15 brain brain NN cord-006870-f5w6fw6q 976 16 code code NN cord-006870-f5w6fw6q 976 17 " " '' cord-006870-f5w6fw6q 976 18 . . . cord-006870-f5w6fw6q 977 1 In in IN cord-006870-f5w6fw6q 977 2 our -PRON- PRP$ cord-006870-f5w6fw6q 977 3 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 977 4 Critical Critical NNP cord-006870-f5w6fw6q 977 5 Care Care NNP cord-006870-f5w6fw6q 977 6 Unit Unit NNP cord-006870-f5w6fw6q 977 7 ( ( -LRB- cord-006870-f5w6fw6q 977 8 NCCU NCCU NNP cord-006870-f5w6fw6q 977 9 ) ) -RRB- cord-006870-f5w6fw6q 977 10 , , , cord-006870-f5w6fw6q 977 11 a a DT cord-006870-f5w6fw6q 977 12 rapid rapid JJ cord-006870-f5w6fw6q 977 13 response response NN cord-006870-f5w6fw6q 977 14 program program NN cord-006870-f5w6fw6q 977 15 is be VBZ cord-006870-f5w6fw6q 977 16 in in IN cord-006870-f5w6fw6q 977 17 place place NN cord-006870-f5w6fw6q 977 18 to to TO cord-006870-f5w6fw6q 977 19 ensure ensure VB cord-006870-f5w6fw6q 977 20 the the DT cord-006870-f5w6fw6q 977 21 safety safety NN cord-006870-f5w6fw6q 977 22 of of IN cord-006870-f5w6fw6q 977 23 23.4 23.4 CD cord-006870-f5w6fw6q 977 24 % % NN cord-006870-f5w6fw6q 977 25 hypertonic hypertonic NN cord-006870-f5w6fw6q 977 26 saline saline NN cord-006870-f5w6fw6q 977 27 's 's POS cord-006870-f5w6fw6q 977 28 use use NN cord-006870-f5w6fw6q 977 29 ( ( -LRB- cord-006870-f5w6fw6q 977 30 high high JJ cord-006870-f5w6fw6q 977 31 risk risk NN cord-006870-f5w6fw6q 977 32 medication medication NN cord-006870-f5w6fw6q 977 33 ) ) -RRB- cord-006870-f5w6fw6q 977 34 and and CC cord-006870-f5w6fw6q 977 35 to to TO cord-006870-f5w6fw6q 977 36 expedite expedite VB cord-006870-f5w6fw6q 977 37 its -PRON- PRP$ cord-006870-f5w6fw6q 977 38 delivery delivery NN cord-006870-f5w6fw6q 977 39 to to IN cord-006870-f5w6fw6q 977 40 the the DT cord-006870-f5w6fw6q 977 41 bedside bedside NN cord-006870-f5w6fw6q 977 42 given give VBN cord-006870-f5w6fw6q 977 43 the the DT cord-006870-f5w6fw6q 977 44 emergent emergent JJ cord-006870-f5w6fw6q 977 45 need need NN cord-006870-f5w6fw6q 977 46 for for IN cord-006870-f5w6fw6q 977 47 this this DT cord-006870-f5w6fw6q 977 48 medication medication NN cord-006870-f5w6fw6q 977 49 when when WRB cord-006870-f5w6fw6q 977 50 ordered order VBN cord-006870-f5w6fw6q 977 51 . . . cord-006870-f5w6fw6q 978 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 978 2 institution institution NN cord-006870-f5w6fw6q 978 3 , , , cord-006870-f5w6fw6q 978 4 however however RB cord-006870-f5w6fw6q 978 5 , , , cord-006870-f5w6fw6q 978 6 is be VBZ cord-006870-f5w6fw6q 978 7 lacking lack VBG cord-006870-f5w6fw6q 978 8 a a DT cord-006870-f5w6fw6q 978 9 more more RBR cord-006870-f5w6fw6q 978 10 holistic holistic JJ cord-006870-f5w6fw6q 978 11 and and CC cord-006870-f5w6fw6q 978 12 structured structured JJ cord-006870-f5w6fw6q 978 13 approach approach NN cord-006870-f5w6fw6q 978 14 to to IN cord-006870-f5w6fw6q 978 15 cerebral cerebral JJ cord-006870-f5w6fw6q 978 16 herniation herniation NN cord-006870-f5w6fw6q 978 17 syndrome syndrome NN cord-006870-f5w6fw6q 978 18 that that WDT cord-006870-f5w6fw6q 978 19 include include VBP cord-006870-f5w6fw6q 978 20 components component NNS cord-006870-f5w6fw6q 978 21 of of IN cord-006870-f5w6fw6q 978 22 Tiers Tiers NNPS cord-006870-f5w6fw6q 978 23 Zero Zero NNP cord-006870-f5w6fw6q 978 24 to to IN cord-006870-f5w6fw6q 978 25 Three three CD cord-006870-f5w6fw6q 978 26 Emergency Emergency NNP cord-006870-f5w6fw6q 978 27 Neurological Neurological NNP cord-006870-f5w6fw6q 978 28 Life Life NNP cord-006870-f5w6fw6q 978 29 Support Support NNP cord-006870-f5w6fw6q 978 30 Elevated elevate VBD cord-006870-f5w6fw6q 978 31 ICP ICP NNP cord-006870-f5w6fw6q 978 32 or or CC cord-006870-f5w6fw6q 978 33 Herniation Herniation NNP cord-006870-f5w6fw6q 978 34 Protocol Protocol NNP cord-006870-f5w6fw6q 978 35 . . . cord-006870-f5w6fw6q 979 1 The the DT cord-006870-f5w6fw6q 979 2 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 979 3 Care Care NNP cord-006870-f5w6fw6q 979 4 Communication Communication NNP cord-006870-f5w6fw6q 979 5 Council Council NNP cord-006870-f5w6fw6q 979 6 consists consist VBZ cord-006870-f5w6fw6q 979 7 of of IN cord-006870-f5w6fw6q 979 8 bedside bedside NN cord-006870-f5w6fw6q 979 9 staff staff NN cord-006870-f5w6fw6q 979 10 nurses nurse NNS cord-006870-f5w6fw6q 979 11 , , , cord-006870-f5w6fw6q 979 12 nursing nursing NN cord-006870-f5w6fw6q 979 13 leadership leadership NN cord-006870-f5w6fw6q 979 14 , , , cord-006870-f5w6fw6q 979 15 Advanced Advanced NNP cord-006870-f5w6fw6q 979 16 Practice Practice NNP cord-006870-f5w6fw6q 979 17 Providers Providers NNPS cord-006870-f5w6fw6q 979 18 ( ( -LRB- cord-006870-f5w6fw6q 979 19 Nurse Nurse NNP cord-006870-f5w6fw6q 979 20 Practitioners Practitioners NNPS cord-006870-f5w6fw6q 979 21 and and CC cord-006870-f5w6fw6q 979 22 Clinical Clinical NNP cord-006870-f5w6fw6q 979 23 Nurse Nurse NNP cord-006870-f5w6fw6q 979 24 Specialist Specialist NNP cord-006870-f5w6fw6q 979 25 ) ) -RRB- cord-006870-f5w6fw6q 979 26 , , , cord-006870-f5w6fw6q 979 27 Pharmacists pharmacist NNS cord-006870-f5w6fw6q 979 28 , , , cord-006870-f5w6fw6q 979 29 Respiratory respiratory JJ cord-006870-f5w6fw6q 979 30 Therapists Therapists NNPS cord-006870-f5w6fw6q 979 31 and and CC cord-006870-f5w6fw6q 979 32 Physicians Physicians NNPS cord-006870-f5w6fw6q 979 33 . . . cord-006870-f5w6fw6q 980 1 The the DT cord-006870-f5w6fw6q 980 2 Council Council NNP cord-006870-f5w6fw6q 980 3 identified identify VBD cord-006870-f5w6fw6q 980 4 processes process NNS cord-006870-f5w6fw6q 980 5 during during IN cord-006870-f5w6fw6q 980 6 neurological neurological JJ cord-006870-f5w6fw6q 980 7 brain brain NN cord-006870-f5w6fw6q 980 8 codes code NNS cord-006870-f5w6fw6q 980 9 that that WDT cord-006870-f5w6fw6q 980 10 could could MD cord-006870-f5w6fw6q 980 11 be be VB cord-006870-f5w6fw6q 980 12 improved improve VBN cord-006870-f5w6fw6q 980 13 as as IN cord-006870-f5w6fw6q 980 14 a a DT cord-006870-f5w6fw6q 980 15 result result NN cord-006870-f5w6fw6q 980 16 of of IN cord-006870-f5w6fw6q 980 17 using use VBG cord-006870-f5w6fw6q 980 18 a a DT cord-006870-f5w6fw6q 980 19 bedside bedside NN cord-006870-f5w6fw6q 980 20 debriefing debriefing NN cord-006870-f5w6fw6q 980 21 tool tool NN cord-006870-f5w6fw6q 980 22 . . . cord-006870-f5w6fw6q 981 1 The the DT cord-006870-f5w6fw6q 981 2 Unit Unit NNP cord-006870-f5w6fw6q 981 3 Leadership Leadership NNP cord-006870-f5w6fw6q 981 4 Council Council NNP cord-006870-f5w6fw6q 981 5 of of IN cord-006870-f5w6fw6q 981 6 the the DT cord-006870-f5w6fw6q 981 7 NCCU NCCU NNP cord-006870-f5w6fw6q 981 8 reviewed review VBN cord-006870-f5w6fw6q 981 9 literature literature NN cord-006870-f5w6fw6q 981 10 on on IN cord-006870-f5w6fw6q 981 11 hospital hospital NN cord-006870-f5w6fw6q 981 12 debriefing debriefing NN cord-006870-f5w6fw6q 981 13 tools tool NNS cord-006870-f5w6fw6q 981 14 and and CC cord-006870-f5w6fw6q 981 15 referenced reference VBD cord-006870-f5w6fw6q 981 16 this this DT cord-006870-f5w6fw6q 981 17 organizations organization NNS cord-006870-f5w6fw6q 981 18 current current JJ cord-006870-f5w6fw6q 981 19 Resuscitation Resuscitation NNP cord-006870-f5w6fw6q 981 20 Debriefing Debriefing NNP cord-006870-f5w6fw6q 981 21 Tool Tool NNP cord-006870-f5w6fw6q 981 22 . . . cord-006870-f5w6fw6q 982 1 From from IN cord-006870-f5w6fw6q 982 2 these these DT cord-006870-f5w6fw6q 982 3 sources source NNS cord-006870-f5w6fw6q 982 4 , , , cord-006870-f5w6fw6q 982 5 a a DT cord-006870-f5w6fw6q 982 6 Brain Brain NNP cord-006870-f5w6fw6q 982 7 Code Code NNP cord-006870-f5w6fw6q 982 8 Debriefing Debriefing NNP cord-006870-f5w6fw6q 982 9 form form NN cord-006870-f5w6fw6q 982 10 was be VBD cord-006870-f5w6fw6q 982 11 constructed construct VBN cord-006870-f5w6fw6q 982 12 . . . cord-006870-f5w6fw6q 983 1 A a DT cord-006870-f5w6fw6q 983 2 clinical clinical JJ cord-006870-f5w6fw6q 983 3 tool tool NN cord-006870-f5w6fw6q 983 4 was be VBD cord-006870-f5w6fw6q 983 5 developed develop VBN cord-006870-f5w6fw6q 983 6 with with IN cord-006870-f5w6fw6q 983 7 the the DT cord-006870-f5w6fw6q 983 8 expectation expectation NN cord-006870-f5w6fw6q 983 9 of of IN cord-006870-f5w6fw6q 983 10 standardizing standardize VBG cord-006870-f5w6fw6q 983 11 the the DT cord-006870-f5w6fw6q 983 12 brain brain NN cord-006870-f5w6fw6q 983 13 code code NN cord-006870-f5w6fw6q 983 14 process process NN cord-006870-f5w6fw6q 983 15 in in IN cord-006870-f5w6fw6q 983 16 this this DT cord-006870-f5w6fw6q 983 17 NCCU NCCU NNP cord-006870-f5w6fw6q 983 18 . . . cord-006870-f5w6fw6q 984 1 The the DT cord-006870-f5w6fw6q 984 2 Brain Brain NNP cord-006870-f5w6fw6q 984 3 Code Code NNP cord-006870-f5w6fw6q 984 4 Debriefing Debriefing NNP cord-006870-f5w6fw6q 984 5 Form Form NNP cord-006870-f5w6fw6q 984 6 will will MD cord-006870-f5w6fw6q 984 7 be be VB cord-006870-f5w6fw6q 984 8 piloted pilot VBN cord-006870-f5w6fw6q 984 9 to to TO cord-006870-f5w6fw6q 984 10 determine determine VB cord-006870-f5w6fw6q 984 11 unit unit NN cord-006870-f5w6fw6q 984 12 and and CC cord-006870-f5w6fw6q 984 13 system system NN cord-006870-f5w6fw6q 984 14 wide wide JJ cord-006870-f5w6fw6q 984 15 value value NN cord-006870-f5w6fw6q 984 16 . . . cord-006870-f5w6fw6q 985 1 Pre pre JJ cord-006870-f5w6fw6q 985 2 - - JJ cord-006870-f5w6fw6q 985 3 and and CC cord-006870-f5w6fw6q 985 4 postimplementation postimplementation NN cord-006870-f5w6fw6q 985 5 data datum NNS cord-006870-f5w6fw6q 985 6 will will MD cord-006870-f5w6fw6q 985 7 be be VB cord-006870-f5w6fw6q 985 8 collected collect VBN cord-006870-f5w6fw6q 985 9 to to TO cord-006870-f5w6fw6q 985 10 discover discover VB cord-006870-f5w6fw6q 985 11 areas area NNS cord-006870-f5w6fw6q 985 12 of of IN cord-006870-f5w6fw6q 985 13 improvement improvement NN cord-006870-f5w6fw6q 985 14 for for IN cord-006870-f5w6fw6q 985 15 optimized optimize VBN cord-006870-f5w6fw6q 985 16 patient patient JJ cord-006870-f5w6fw6q 985 17 care care NN cord-006870-f5w6fw6q 985 18 . . . cord-006870-f5w6fw6q 986 1 Through through IN cord-006870-f5w6fw6q 986 2 the the DT cord-006870-f5w6fw6q 986 3 development development NN cord-006870-f5w6fw6q 986 4 of of IN cord-006870-f5w6fw6q 986 5 this this DT cord-006870-f5w6fw6q 986 6 debriefing debriefing NN cord-006870-f5w6fw6q 986 7 tool tool NN cord-006870-f5w6fw6q 986 8 , , , cord-006870-f5w6fw6q 986 9 it -PRON- PRP cord-006870-f5w6fw6q 986 10 was be VBD cord-006870-f5w6fw6q 986 11 ascertained ascertain VBN cord-006870-f5w6fw6q 986 12 that that IN cord-006870-f5w6fw6q 986 13 a a DT cord-006870-f5w6fw6q 986 14 Clinical Clinical NNP cord-006870-f5w6fw6q 986 15 Practice Practice NNP cord-006870-f5w6fw6q 986 16 Guideline Guideline NNP cord-006870-f5w6fw6q 986 17 for for IN cord-006870-f5w6fw6q 986 18 impending impend VBG cord-006870-f5w6fw6q 986 19 cerebral cerebral JJ cord-006870-f5w6fw6q 986 20 herniation herniation NN cord-006870-f5w6fw6q 986 21 would would MD cord-006870-f5w6fw6q 986 22 be be VB cord-006870-f5w6fw6q 986 23 beneficial beneficial JJ cord-006870-f5w6fw6q 986 24 to to TO cord-006870-f5w6fw6q 986 25 further further JJ cord-006870-f5w6fw6q 986 26 guide guide VB cord-006870-f5w6fw6q 986 27 and and CC cord-006870-f5w6fw6q 986 28 direct direct JJ cord-006870-f5w6fw6q 986 29 evidence evidence NN cord-006870-f5w6fw6q 986 30 - - HYPH cord-006870-f5w6fw6q 986 31 based base VBN cord-006870-f5w6fw6q 986 32 care care NN cord-006870-f5w6fw6q 986 33 . . . cord-006870-f5w6fw6q 987 1 Thus thus RB cord-006870-f5w6fw6q 987 2 , , , cord-006870-f5w6fw6q 987 3 a a DT cord-006870-f5w6fw6q 987 4 preliminary preliminary JJ cord-006870-f5w6fw6q 987 5 algorithm algorithm NN cord-006870-f5w6fw6q 987 6 for for IN cord-006870-f5w6fw6q 987 7 identification identification NN cord-006870-f5w6fw6q 987 8 and and CC cord-006870-f5w6fw6q 987 9 emergency emergency NN cord-006870-f5w6fw6q 987 10 treatment treatment NN cord-006870-f5w6fw6q 987 11 is be VBZ cord-006870-f5w6fw6q 987 12 in in IN cord-006870-f5w6fw6q 987 13 process process NN cord-006870-f5w6fw6q 987 14 . . . cord-006870-f5w6fw6q 988 1 The the DT cord-006870-f5w6fw6q 988 2 Americas Americas NNPS cord-006870-f5w6fw6q 988 3 Medical Medical NNP cord-006870-f5w6fw6q 988 4 Center Center NNP cord-006870-f5w6fw6q 988 5 is be VBZ cord-006870-f5w6fw6q 988 6 a a DT cord-006870-f5w6fw6q 988 7 212-bed 212-bed CD cord-006870-f5w6fw6q 988 8 tertiary tertiary JJ cord-006870-f5w6fw6q 988 9 hospital hospital NN cord-006870-f5w6fw6q 988 10 complex complex NN cord-006870-f5w6fw6q 988 11 , , , cord-006870-f5w6fw6q 988 12 located locate VBN cord-006870-f5w6fw6q 988 13 in in IN cord-006870-f5w6fw6q 988 14 the the DT cord-006870-f5w6fw6q 988 15 city city NN cord-006870-f5w6fw6q 988 16 of of IN cord-006870-f5w6fw6q 988 17 Rio Rio NNP cord-006870-f5w6fw6q 988 18 de de NNP cord-006870-f5w6fw6q 988 19 Janeiro Janeiro NNP cord-006870-f5w6fw6q 988 20 . . . cord-006870-f5w6fw6q 989 1 The the DT cord-006870-f5w6fw6q 989 2 center center NN cord-006870-f5w6fw6q 989 3 was be VBD cord-006870-f5w6fw6q 989 4 elected elect VBN cord-006870-f5w6fw6q 989 5 by by IN cord-006870-f5w6fw6q 989 6 the the DT cord-006870-f5w6fw6q 989 7 International International NNP cord-006870-f5w6fw6q 989 8 and and CC cord-006870-f5w6fw6q 989 9 the the DT cord-006870-f5w6fw6q 989 10 Brazilian brazilian JJ cord-006870-f5w6fw6q 989 11 Olympic Olympic NNP cord-006870-f5w6fw6q 989 12 Committees Committees NNPS cord-006870-f5w6fw6q 989 13 as as IN cord-006870-f5w6fw6q 989 14 the the DT cord-006870-f5w6fw6q 989 15 referral referral JJ cord-006870-f5w6fw6q 989 16 hospital hospital NN cord-006870-f5w6fw6q 989 17 for for IN cord-006870-f5w6fw6q 989 18 the the DT cord-006870-f5w6fw6q 989 19 Olympic Olympic NNP cord-006870-f5w6fw6q 989 20 Family Family NNP cord-006870-f5w6fw6q 989 21 ( ( -LRB- cord-006870-f5w6fw6q 989 22 OF of IN cord-006870-f5w6fw6q 989 23 ) ) -RRB- cord-006870-f5w6fw6q 989 24 , , , cord-006870-f5w6fw6q 989 25 comprised comprise VBN cord-006870-f5w6fw6q 989 26 of of IN cord-006870-f5w6fw6q 989 27 athletes athlete NNS cord-006870-f5w6fw6q 989 28 and and CC cord-006870-f5w6fw6q 989 29 their -PRON- PRP$ cord-006870-f5w6fw6q 989 30 crews crew NNS cord-006870-f5w6fw6q 989 31 , , , cord-006870-f5w6fw6q 989 32 support support NN cord-006870-f5w6fw6q 989 33 and and CC cord-006870-f5w6fw6q 989 34 technical technical JJ cord-006870-f5w6fw6q 989 35 personnel personnel NNS cord-006870-f5w6fw6q 989 36 , , , cord-006870-f5w6fw6q 989 37 credentialed credentialed JJ cord-006870-f5w6fw6q 989 38 media medium NNS cord-006870-f5w6fw6q 989 39 and and CC cord-006870-f5w6fw6q 989 40 credentialed credentialed JJ cord-006870-f5w6fw6q 989 41 governmental governmental JJ cord-006870-f5w6fw6q 989 42 representatives representative NNS cord-006870-f5w6fw6q 989 43 from from IN cord-006870-f5w6fw6q 989 44 the the DT cord-006870-f5w6fw6q 989 45 participating participate VBG cord-006870-f5w6fw6q 989 46 countries country NNS cord-006870-f5w6fw6q 989 47 . . . cord-006870-f5w6fw6q 990 1 The the DT cord-006870-f5w6fw6q 990 2 Neurology Neurology NNP cord-006870-f5w6fw6q 990 3 and and CC cord-006870-f5w6fw6q 990 4 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 990 5 care care NN cord-006870-f5w6fw6q 990 6 teams team NNS cord-006870-f5w6fw6q 990 7 were be VBD cord-006870-f5w6fw6q 990 8 selected select VBN cord-006870-f5w6fw6q 990 9 to to TO cord-006870-f5w6fw6q 990 10 head head VB cord-006870-f5w6fw6q 990 11 a a DT cord-006870-f5w6fw6q 990 12 comprehensive comprehensive JJ cord-006870-f5w6fw6q 990 13 program program NN cord-006870-f5w6fw6q 990 14 of of IN cord-006870-f5w6fw6q 990 15 acute acute JJ cord-006870-f5w6fw6q 990 16 emergency emergency NN cord-006870-f5w6fw6q 990 17 neurology neurology NN cord-006870-f5w6fw6q 990 18 , , , cord-006870-f5w6fw6q 990 19 including include VBG cord-006870-f5w6fw6q 990 20 a a DT cord-006870-f5w6fw6q 990 21 10-bed 10-bed CD cord-006870-f5w6fw6q 990 22 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 990 23 care care NN cord-006870-f5w6fw6q 990 24 unit unit NN cord-006870-f5w6fw6q 990 25 ( ( -LRB- cord-006870-f5w6fw6q 990 26 NICU NICU NNP cord-006870-f5w6fw6q 990 27 ) ) -RRB- cord-006870-f5w6fw6q 990 28 , , , cord-006870-f5w6fw6q 990 29 and and CC cord-006870-f5w6fw6q 990 30 24 24 CD cord-006870-f5w6fw6q 990 31 - - SYM cord-006870-f5w6fw6q 990 32 7 7 CD cord-006870-f5w6fw6q 990 33 emergency emergency NN cord-006870-f5w6fw6q 990 34 neurology neurology NN cord-006870-f5w6fw6q 990 35 service service NN cord-006870-f5w6fw6q 990 36 . . . cord-006870-f5w6fw6q 991 1 We -PRON- PRP cord-006870-f5w6fw6q 991 2 hereby hereby RB cord-006870-f5w6fw6q 991 3 describe describe VBP cord-006870-f5w6fw6q 991 4 our -PRON- PRP$ cord-006870-f5w6fw6q 991 5 experience experience NN cord-006870-f5w6fw6q 991 6 during during IN cord-006870-f5w6fw6q 991 7 the the DT cord-006870-f5w6fw6q 991 8 2016 2016 CD cord-006870-f5w6fw6q 991 9 Olympic Olympic NNP cord-006870-f5w6fw6q 991 10 Games Games NNPS cord-006870-f5w6fw6q 991 11 in in IN cord-006870-f5w6fw6q 991 12 Rio Rio NNP cord-006870-f5w6fw6q 991 13 de de NNP cord-006870-f5w6fw6q 991 14 Janeiro Janeiro NNP cord-006870-f5w6fw6q 991 15 , , , cord-006870-f5w6fw6q 991 16 Brazil Brazil NNP cord-006870-f5w6fw6q 991 17 Results result VBZ cord-006870-f5w6fw6q 992 1 63 63 CD cord-006870-f5w6fw6q 992 2 neurological neurological JJ cord-006870-f5w6fw6q 992 3 assessments assessment NNS cord-006870-f5w6fw6q 992 4 were be VBD cord-006870-f5w6fw6q 992 5 conducted conduct VBN cord-006870-f5w6fw6q 992 6 in in IN cord-006870-f5w6fw6q 992 7 patients patient NNS cord-006870-f5w6fw6q 992 8 from from IN cord-006870-f5w6fw6q 992 9 the the DT cord-006870-f5w6fw6q 992 10 OF of NN cord-006870-f5w6fw6q 992 11 , , , cord-006870-f5w6fw6q 992 12 22 22 CD cord-006870-f5w6fw6q 992 13 of of IN cord-006870-f5w6fw6q 992 14 these these DT cord-006870-f5w6fw6q 992 15 involving involve VBG cord-006870-f5w6fw6q 992 16 athletes athlete NNS cord-006870-f5w6fw6q 992 17 from from IN cord-006870-f5w6fw6q 992 18 19 19 CD cord-006870-f5w6fw6q 992 19 countries country NNS cord-006870-f5w6fw6q 992 20 . . . cord-006870-f5w6fw6q 993 1 The the DT cord-006870-f5w6fw6q 993 2 most most RBS cord-006870-f5w6fw6q 993 3 common common JJ cord-006870-f5w6fw6q 993 4 reason reason NN cord-006870-f5w6fw6q 993 5 among among IN cord-006870-f5w6fw6q 993 6 athletes athlete NNS cord-006870-f5w6fw6q 993 7 were be VBD cord-006870-f5w6fw6q 993 8 traumatic traumatic JJ cord-006870-f5w6fw6q 993 9 brain brain NN cord-006870-f5w6fw6q 993 10 injuries injury NNS cord-006870-f5w6fw6q 993 11 ( ( -LRB- cord-006870-f5w6fw6q 993 12 TBI TBI NNP cord-006870-f5w6fw6q 993 13 ) ) -RRB- cord-006870-f5w6fw6q 993 14 , , , cord-006870-f5w6fw6q 993 15 with with IN cord-006870-f5w6fw6q 993 16 6 6 CD cord-006870-f5w6fw6q 993 17 politraumas politraumas NN cord-006870-f5w6fw6q 993 18 ( ( -LRB- cord-006870-f5w6fw6q 993 19 all all DT cord-006870-f5w6fw6q 993 20 involving involve VBG cord-006870-f5w6fw6q 993 21 cycling cycle VBG cord-006870-f5w6fw6q 993 22 ) ) -RRB- cord-006870-f5w6fw6q 993 23 , , , cord-006870-f5w6fw6q 993 24 7 7 CD cord-006870-f5w6fw6q 993 25 mild mild JJ cord-006870-f5w6fw6q 993 26 TBI TBI NNP cord-006870-f5w6fw6q 993 27 ( ( -LRB- cord-006870-f5w6fw6q 993 28 3 3 CD cord-006870-f5w6fw6q 993 29 of of IN cord-006870-f5w6fw6q 993 30 boxing boxing NN cord-006870-f5w6fw6q 993 31 , , , cord-006870-f5w6fw6q 993 32 2 2 CD cord-006870-f5w6fw6q 993 33 of of IN cord-006870-f5w6fw6q 993 34 field field NN cord-006870-f5w6fw6q 993 35 hockey hockey NN cord-006870-f5w6fw6q 993 36 , , , cord-006870-f5w6fw6q 993 37 1 1 CD cord-006870-f5w6fw6q 993 38 of of IN cord-006870-f5w6fw6q 993 39 rowing rowing NN cord-006870-f5w6fw6q 993 40 and and CC cord-006870-f5w6fw6q 993 41 1 1 CD cord-006870-f5w6fw6q 993 42 of of IN cord-006870-f5w6fw6q 993 43 cycling cycling NN cord-006870-f5w6fw6q 993 44 ) ) -RRB- cord-006870-f5w6fw6q 993 45 and and CC cord-006870-f5w6fw6q 993 46 2 2 CD cord-006870-f5w6fw6q 993 47 moderate moderate JJ cord-006870-f5w6fw6q 993 48 TBI TBI NNP cord-006870-f5w6fw6q 993 49 ( ( -LRB- cord-006870-f5w6fw6q 993 50 cycling cycling NN cord-006870-f5w6fw6q 993 51 and and CC cord-006870-f5w6fw6q 993 52 water water NN cord-006870-f5w6fw6q 993 53 polo polo NN cord-006870-f5w6fw6q 993 54 ) ) -RRB- cord-006870-f5w6fw6q 993 55 . . . cord-006870-f5w6fw6q 994 1 Three three CD cord-006870-f5w6fw6q 994 2 patients patient NNS cord-006870-f5w6fw6q 994 3 were be VBD cord-006870-f5w6fw6q 994 4 admitted admit VBN cord-006870-f5w6fw6q 994 5 to to IN cord-006870-f5w6fw6q 994 6 the the DT cord-006870-f5w6fw6q 994 7 NICU NICU NNP cord-006870-f5w6fw6q 994 8 : : : cord-006870-f5w6fw6q 994 9 2 2 CD cord-006870-f5w6fw6q 994 10 ischemic ischemic JJ cord-006870-f5w6fw6q 994 11 strokes stroke NNS cord-006870-f5w6fw6q 994 12 and and CC cord-006870-f5w6fw6q 994 13 3 3 CD cord-006870-f5w6fw6q 994 14 politraumas politraumas NN cord-006870-f5w6fw6q 994 15 with with IN cord-006870-f5w6fw6q 994 16 TBI TBI NNP cord-006870-f5w6fw6q 994 17 . . . cord-006870-f5w6fw6q 995 1 Motor motor NN cord-006870-f5w6fw6q 995 2 vehicle vehicle NN cord-006870-f5w6fw6q 995 3 accidents accident NNS cord-006870-f5w6fw6q 995 4 with with IN cord-006870-f5w6fw6q 995 5 associated associate VBN cord-006870-f5w6fw6q 995 6 TBI TBI NNP cord-006870-f5w6fw6q 995 7 involving involve VBG cord-006870-f5w6fw6q 995 8 the the DT cord-006870-f5w6fw6q 995 9 OF of NN cord-006870-f5w6fw6q 995 10 were be VBD cord-006870-f5w6fw6q 995 11 surprisingly surprisingly RB cord-006870-f5w6fw6q 995 12 frequent frequent JJ cord-006870-f5w6fw6q 995 13 , , , cord-006870-f5w6fw6q 995 14 with with IN cord-006870-f5w6fw6q 995 15 10 10 CD cord-006870-f5w6fw6q 995 16 assessments assessment NNS cord-006870-f5w6fw6q 995 17 , , , cord-006870-f5w6fw6q 995 18 none none NN cord-006870-f5w6fw6q 995 19 requiring require VBG cord-006870-f5w6fw6q 995 20 admissions admission NNS cord-006870-f5w6fw6q 995 21 . . . cord-006870-f5w6fw6q 996 1 Finally finally RB cord-006870-f5w6fw6q 996 2 , , , cord-006870-f5w6fw6q 996 3 39 39 CD cord-006870-f5w6fw6q 996 4 CT CT NNP cord-006870-f5w6fw6q 996 5 scans scan NNS cord-006870-f5w6fw6q 996 6 of of IN cord-006870-f5w6fw6q 996 7 head head NN cord-006870-f5w6fw6q 996 8 , , , cord-006870-f5w6fw6q 996 9 22 22 CD cord-006870-f5w6fw6q 996 10 CT CT NNP cord-006870-f5w6fw6q 996 11 scans scan NNS cord-006870-f5w6fw6q 996 12 of of IN cord-006870-f5w6fw6q 996 13 the the DT cord-006870-f5w6fw6q 996 14 cervical cervical JJ cord-006870-f5w6fw6q 996 15 spine spine NN cord-006870-f5w6fw6q 996 16 and and CC cord-006870-f5w6fw6q 996 17 14 14 CD cord-006870-f5w6fw6q 996 18 MRI MRI NNP cord-006870-f5w6fw6q 996 19 scans scan NNS cord-006870-f5w6fw6q 996 20 ( ( -LRB- cord-006870-f5w6fw6q 996 21 3 3 CD cord-006870-f5w6fw6q 996 22 brain brain NN cord-006870-f5w6fw6q 996 23 and and CC cord-006870-f5w6fw6q 996 24 11 11 CD cord-006870-f5w6fw6q 996 25 spine spine NN cord-006870-f5w6fw6q 996 26 MRI MRI NNP cord-006870-f5w6fw6q 996 27 ) ) -RRB- cord-006870-f5w6fw6q 996 28 were be VBD cord-006870-f5w6fw6q 996 29 performed perform VBN cord-006870-f5w6fw6q 996 30 to to TO cord-006870-f5w6fw6q 996 31 assess assess VB cord-006870-f5w6fw6q 996 32 the the DT cord-006870-f5w6fw6q 996 33 patients patient NNS cord-006870-f5w6fw6q 996 34 . . . cord-006870-f5w6fw6q 997 1 Of of IN cord-006870-f5w6fw6q 997 2 note note NN cord-006870-f5w6fw6q 997 3 , , , cord-006870-f5w6fw6q 997 4 cases case NNS cord-006870-f5w6fw6q 997 5 of of IN cord-006870-f5w6fw6q 997 6 seizures seizure NNS cord-006870-f5w6fw6q 997 7 , , , cord-006870-f5w6fw6q 997 8 functional functional JJ cord-006870-f5w6fw6q 997 9 deficits deficit NNS cord-006870-f5w6fw6q 997 10 , , , cord-006870-f5w6fw6q 997 11 multiple multiple JJ cord-006870-f5w6fw6q 997 12 sclerosis sclerosis NN cord-006870-f5w6fw6q 997 13 flare flare NN cord-006870-f5w6fw6q 997 14 and and CC cord-006870-f5w6fw6q 997 15 psychiatric psychiatric JJ cord-006870-f5w6fw6q 997 16 complaints complaint NNS cord-006870-f5w6fw6q 997 17 were be VBD cord-006870-f5w6fw6q 997 18 observed observe VBN cord-006870-f5w6fw6q 997 19 affecting affect VBG cord-006870-f5w6fw6q 997 20 the the DT cord-006870-f5w6fw6q 997 21 OF of NN cord-006870-f5w6fw6q 997 22 . . . cord-006870-f5w6fw6q 998 1 Not not RB cord-006870-f5w6fw6q 998 2 only only RB cord-006870-f5w6fw6q 998 3 that that IN cord-006870-f5w6fw6q 998 4 multiple multiple JJ cord-006870-f5w6fw6q 998 5 sports sport NNS cord-006870-f5w6fw6q 998 6 - - HYPH cord-006870-f5w6fw6q 998 7 related relate VBN cord-006870-f5w6fw6q 998 8 injuries injury NNS cord-006870-f5w6fw6q 998 9 were be VBD cord-006870-f5w6fw6q 998 10 observed observe VBN cord-006870-f5w6fw6q 998 11 , , , cord-006870-f5w6fw6q 998 12 cases case NNS cord-006870-f5w6fw6q 998 13 of of IN cord-006870-f5w6fw6q 998 14 diverse diverse JJ cord-006870-f5w6fw6q 998 15 acute acute JJ cord-006870-f5w6fw6q 998 16 neurological neurological JJ cord-006870-f5w6fw6q 998 17 issues issue NNS cord-006870-f5w6fw6q 998 18 were be VBD cord-006870-f5w6fw6q 998 19 reported report VBN cord-006870-f5w6fw6q 998 20 involving involve VBG cord-006870-f5w6fw6q 998 21 members member NNS cord-006870-f5w6fw6q 998 22 of of IN cord-006870-f5w6fw6q 998 23 the the DT cord-006870-f5w6fw6q 998 24 OF of NN cord-006870-f5w6fw6q 998 25 . . . cord-006870-f5w6fw6q 999 1 Olympic Olympic NNP cord-006870-f5w6fw6q 999 2 Games Games NNPS cord-006870-f5w6fw6q 999 3 are be VBP cord-006870-f5w6fw6q 999 4 complex complex JJ cord-006870-f5w6fw6q 999 5 events event NNS cord-006870-f5w6fw6q 999 6 mobilizing mobilize VBG cord-006870-f5w6fw6q 999 7 thousands thousand NNS cord-006870-f5w6fw6q 999 8 of of IN cord-006870-f5w6fw6q 999 9 people people NNS cord-006870-f5w6fw6q 999 10 , , , cord-006870-f5w6fw6q 999 11 and and CC cord-006870-f5w6fw6q 999 12 a a DT cord-006870-f5w6fw6q 999 13 comprehensive comprehensive JJ cord-006870-f5w6fw6q 999 14 and and CC cord-006870-f5w6fw6q 999 15 detailed detailed JJ cord-006870-f5w6fw6q 999 16 plan plan NN cord-006870-f5w6fw6q 999 17 for for IN cord-006870-f5w6fw6q 999 18 neurological neurological JJ cord-006870-f5w6fw6q 999 19 emergencies emergency NNS cord-006870-f5w6fw6q 999 20 is be VBZ cord-006870-f5w6fw6q 999 21 of of IN cord-006870-f5w6fw6q 999 22 extreme extreme JJ cord-006870-f5w6fw6q 999 23 importance importance NN cord-006870-f5w6fw6q 999 24 The the DT cord-006870-f5w6fw6q 999 25 term term NN cord-006870-f5w6fw6q 999 26 " " `` cord-006870-f5w6fw6q 999 27 handoff handoff NN cord-006870-f5w6fw6q 999 28 " " '' cord-006870-f5w6fw6q 999 29 has have VBZ cord-006870-f5w6fw6q 999 30 been be VBN cord-006870-f5w6fw6q 999 31 defined define VBN cord-006870-f5w6fw6q 999 32 as as IN cord-006870-f5w6fw6q 999 33 the the DT cord-006870-f5w6fw6q 999 34 " " `` cord-006870-f5w6fw6q 999 35 transfer transfer NN cord-006870-f5w6fw6q 999 36 and and CC cord-006870-f5w6fw6q 999 37 acceptance acceptance NN cord-006870-f5w6fw6q 999 38 of of IN cord-006870-f5w6fw6q 999 39 responsibility responsibility NN cord-006870-f5w6fw6q 999 40 for for IN cord-006870-f5w6fw6q 999 41 patient patient JJ cord-006870-f5w6fw6q 999 42 care care NN cord-006870-f5w6fw6q 999 43 that that WDT cord-006870-f5w6fw6q 999 44 is be VBZ cord-006870-f5w6fw6q 999 45 achieved achieve VBN cord-006870-f5w6fw6q 999 46 through through IN cord-006870-f5w6fw6q 999 47 effective effective JJ cord-006870-f5w6fw6q 999 48 communication communication NN cord-006870-f5w6fw6q 999 49 , , , cord-006870-f5w6fw6q 999 50 passing pass VBG cord-006870-f5w6fw6q 999 51 patient patient NN cord-006870-f5w6fw6q 999 52 - - HYPH cord-006870-f5w6fw6q 999 53 specific specific JJ cord-006870-f5w6fw6q 999 54 information information NN cord-006870-f5w6fw6q 999 55 from from IN cord-006870-f5w6fw6q 999 56 one one CD cord-006870-f5w6fw6q 999 57 caregiver caregiver NN cord-006870-f5w6fw6q 999 58 or or CC cord-006870-f5w6fw6q 999 59 team team NN cord-006870-f5w6fw6q 999 60 of of IN cord-006870-f5w6fw6q 999 61 caregivers caregiver NNS cord-006870-f5w6fw6q 999 62 to to IN cord-006870-f5w6fw6q 999 63 another another DT cord-006870-f5w6fw6q 999 64 to to TO cord-006870-f5w6fw6q 999 65 ensure ensure VB cord-006870-f5w6fw6q 999 66 the the DT cord-006870-f5w6fw6q 999 67 continuity continuity NN cord-006870-f5w6fw6q 999 68 and and CC cord-006870-f5w6fw6q 999 69 safety safety NN cord-006870-f5w6fw6q 999 70 of of IN cord-006870-f5w6fw6q 999 71 the the DT cord-006870-f5w6fw6q 999 72 patient patient NN cord-006870-f5w6fw6q 999 73 's 's POS cord-006870-f5w6fw6q 999 74 care care NN cord-006870-f5w6fw6q 999 75 " " '' cord-006870-f5w6fw6q 999 76 ( ( -LRB- cord-006870-f5w6fw6q 999 77 Patterson Patterson NNP cord-006870-f5w6fw6q 999 78 and and CC cord-006870-f5w6fw6q 999 79 Wears Wears NNP cord-006870-f5w6fw6q 999 80 , , , cord-006870-f5w6fw6q 999 81 2010 2010 CD cord-006870-f5w6fw6q 999 82 ) ) -RRB- cord-006870-f5w6fw6q 999 83 . . . cord-006870-f5w6fw6q 1000 1 The the DT cord-006870-f5w6fw6q 1000 2 Joint Joint NNP cord-006870-f5w6fw6q 1000 3 Commission Commission NNP cord-006870-f5w6fw6q 1000 4 reported report VBD cord-006870-f5w6fw6q 1000 5 that that IN cord-006870-f5w6fw6q 1000 6 two two CD cord-006870-f5w6fw6q 1000 7 - - HYPH cord-006870-f5w6fw6q 1000 8 thirds third NNS cord-006870-f5w6fw6q 1000 9 of of IN cord-006870-f5w6fw6q 1000 10 sentinel sentinel JJ cord-006870-f5w6fw6q 1000 11 events event NNS cord-006870-f5w6fw6q 1000 12 occur occur VBP cord-006870-f5w6fw6q 1000 13 at at IN cord-006870-f5w6fw6q 1000 14 the the DT cord-006870-f5w6fw6q 1000 15 time time NN cord-006870-f5w6fw6q 1000 16 of of IN cord-006870-f5w6fw6q 1000 17 patient patient JJ cord-006870-f5w6fw6q 1000 18 handoff handoff NN cord-006870-f5w6fw6q 1000 19 , , , cord-006870-f5w6fw6q 1000 20 which which WDT cord-006870-f5w6fw6q 1000 21 led lead VBD cord-006870-f5w6fw6q 1000 22 to to IN cord-006870-f5w6fw6q 1000 23 a a DT cord-006870-f5w6fw6q 1000 24 National National NNP cord-006870-f5w6fw6q 1000 25 Patient Patient NNP cord-006870-f5w6fw6q 1000 26 Safety Safety NNP cord-006870-f5w6fw6q 1000 27 Goal Goal NNP cord-006870-f5w6fw6q 1000 28 , , , cord-006870-f5w6fw6q 1000 29 requiring require VBG cord-006870-f5w6fw6q 1000 30 standardized standardized JJ cord-006870-f5w6fw6q 1000 31 process process NN cord-006870-f5w6fw6q 1000 32 for for IN cord-006870-f5w6fw6q 1000 33 handoffs handoff NNS cord-006870-f5w6fw6q 1000 34 ( ( -LRB- cord-006870-f5w6fw6q 1000 35 The the DT cord-006870-f5w6fw6q 1000 36 Joint Joint NNP cord-006870-f5w6fw6q 1000 37 Commission Commission NNP cord-006870-f5w6fw6q 1000 38 on on IN cord-006870-f5w6fw6q 1000 39 Accreditation Accreditation NNP cord-006870-f5w6fw6q 1000 40 of of IN cord-006870-f5w6fw6q 1000 41 Healthcare Healthcare NNP cord-006870-f5w6fw6q 1000 42 Organizations Organizations NNPS cord-006870-f5w6fw6q 1000 43 , , , cord-006870-f5w6fw6q 1000 44 2006 2006 CD cord-006870-f5w6fw6q 1000 45 ) ) -RRB- cord-006870-f5w6fw6q 1000 46 . . . cord-006870-f5w6fw6q 1001 1 To to TO cord-006870-f5w6fw6q 1001 2 support support VB cord-006870-f5w6fw6q 1001 3 this this DT cord-006870-f5w6fw6q 1001 4 NPSG NPSG NNP cord-006870-f5w6fw6q 1001 5 , , , cord-006870-f5w6fw6q 1001 6 a a DT cord-006870-f5w6fw6q 1001 7 NCCU NCCU NNP cord-006870-f5w6fw6q 1001 8 specific specific JJ cord-006870-f5w6fw6q 1001 9 handoff handoff NN cord-006870-f5w6fw6q 1001 10 tool tool NN cord-006870-f5w6fw6q 1001 11 and and CC cord-006870-f5w6fw6q 1001 12 timeout timeout NN cord-006870-f5w6fw6q 1001 13 process process NN cord-006870-f5w6fw6q 1001 14 were be VBD cord-006870-f5w6fw6q 1001 15 created create VBN cord-006870-f5w6fw6q 1001 16 to to TO cord-006870-f5w6fw6q 1001 17 support support VB cord-006870-f5w6fw6q 1001 18 the the DT cord-006870-f5w6fw6q 1001 19 transition transition NN cord-006870-f5w6fw6q 1001 20 from from IN cord-006870-f5w6fw6q 1001 21 OR or CC cord-006870-f5w6fw6q 1001 22 to to IN cord-006870-f5w6fw6q 1001 23 NCCU NCCU NNP cord-006870-f5w6fw6q 1001 24 . . . cord-006870-f5w6fw6q 1002 1 NCCU NCCU NNP cord-006870-f5w6fw6q 1002 2 postoperative postoperative JJ cord-006870-f5w6fw6q 1002 3 handoffs handoff NNS cord-006870-f5w6fw6q 1002 4 were be VBD cord-006870-f5w6fw6q 1002 5 identified identify VBN cord-006870-f5w6fw6q 1002 6 as as IN cord-006870-f5w6fw6q 1002 7 an an DT cord-006870-f5w6fw6q 1002 8 area area NN cord-006870-f5w6fw6q 1002 9 to to TO cord-006870-f5w6fw6q 1002 10 enhance enhance VB cord-006870-f5w6fw6q 1002 11 staff staff NN cord-006870-f5w6fw6q 1002 12 satisfaction satisfaction NN cord-006870-f5w6fw6q 1002 13 and and CC cord-006870-f5w6fw6q 1002 14 patient patient JJ cord-006870-f5w6fw6q 1002 15 safety safety NN cord-006870-f5w6fw6q 1002 16 . . . cord-006870-f5w6fw6q 1003 1 Baseline baseline JJ cord-006870-f5w6fw6q 1003 2 data datum NNS cord-006870-f5w6fw6q 1003 3 to to TO cord-006870-f5w6fw6q 1003 4 evaluate evaluate VB cord-006870-f5w6fw6q 1003 5 the the DT cord-006870-f5w6fw6q 1003 6 frequency frequency NN cord-006870-f5w6fw6q 1003 7 of of IN cord-006870-f5w6fw6q 1003 8 neurosurgery neurosurgery NNP cord-006870-f5w6fw6q 1003 9 report report NN cord-006870-f5w6fw6q 1003 10 was be VBD cord-006870-f5w6fw6q 1003 11 performed perform VBN cord-006870-f5w6fw6q 1003 12 in in IN cord-006870-f5w6fw6q 1003 13 May May NNP cord-006870-f5w6fw6q 1003 14 2017 2017 CD cord-006870-f5w6fw6q 1003 15 . . . cord-006870-f5w6fw6q 1004 1 Using use VBG cord-006870-f5w6fw6q 1004 2 a a DT cord-006870-f5w6fw6q 1004 3 Qualtrics Qualtrics NNP cord-006870-f5w6fw6q 1004 4 survey survey NN cord-006870-f5w6fw6q 1004 5 in in IN cord-006870-f5w6fw6q 1004 6 June June NNP cord-006870-f5w6fw6q 1004 7 2017 2017 CD cord-006870-f5w6fw6q 1004 8 , , , cord-006870-f5w6fw6q 1004 9 staff staff NN cord-006870-f5w6fw6q 1004 10 satisfaction satisfaction NN cord-006870-f5w6fw6q 1004 11 with with IN cord-006870-f5w6fw6q 1004 12 current current JJ cord-006870-f5w6fw6q 1004 13 NS NS NNP cord-006870-f5w6fw6q 1005 1 OR or CC cord-006870-f5w6fw6q 1005 2 report report NN cord-006870-f5w6fw6q 1005 3 was be VBD cord-006870-f5w6fw6q 1005 4 obtained obtain VBN cord-006870-f5w6fw6q 1005 5 from from IN cord-006870-f5w6fw6q 1005 6 NCCU NCCU NNP cord-006870-f5w6fw6q 1005 7 RNs RNs NNPS cord-006870-f5w6fw6q 1005 8 , , , cord-006870-f5w6fw6q 1005 9 NPs NPs NNP cord-006870-f5w6fw6q 1005 10 , , , cord-006870-f5w6fw6q 1005 11 and and CC cord-006870-f5w6fw6q 1005 12 fellows fellow NNS cord-006870-f5w6fw6q 1005 13 evaluating evaluate VBG cord-006870-f5w6fw6q 1005 14 whether whether IN cord-006870-f5w6fw6q 1005 15 they -PRON- PRP cord-006870-f5w6fw6q 1005 16 felt feel VBD cord-006870-f5w6fw6q 1005 17 they -PRON- PRP cord-006870-f5w6fw6q 1005 18 received receive VBD cord-006870-f5w6fw6q 1005 19 : : : cord-006870-f5w6fw6q 1005 20 accurate accurate JJ cord-006870-f5w6fw6q 1005 21 medical medical JJ cord-006870-f5w6fw6q 1005 22 history history NN cord-006870-f5w6fw6q 1005 23 , , , cord-006870-f5w6fw6q 1005 24 accurate accurate JJ cord-006870-f5w6fw6q 1005 25 information information NN cord-006870-f5w6fw6q 1005 26 about about IN cord-006870-f5w6fw6q 1005 27 performed perform VBN cord-006870-f5w6fw6q 1005 28 procedure procedure NN cord-006870-f5w6fw6q 1005 29 , , , cord-006870-f5w6fw6q 1005 30 sufficient sufficient JJ cord-006870-f5w6fw6q 1005 31 handoff handoff NN cord-006870-f5w6fw6q 1005 32 for for IN cord-006870-f5w6fw6q 1005 33 patient patient JJ cord-006870-f5w6fw6q 1005 34 care care NN cord-006870-f5w6fw6q 1005 35 , , , cord-006870-f5w6fw6q 1005 36 specific specific JJ cord-006870-f5w6fw6q 1005 37 patient patient JJ cord-006870-f5w6fw6q 1005 38 goals goal NNS cord-006870-f5w6fw6q 1005 39 , , , cord-006870-f5w6fw6q 1005 40 recent recent JJ cord-006870-f5w6fw6q 1005 41 pharmacological pharmacological JJ cord-006870-f5w6fw6q 1005 42 intervention intervention NN cord-006870-f5w6fw6q 1005 43 , , , cord-006870-f5w6fw6q 1005 44 anticipated anticipate VBN cord-006870-f5w6fw6q 1005 45 concerns concern NNS cord-006870-f5w6fw6q 1005 46 regarding regard VBG cord-006870-f5w6fw6q 1005 47 diagnosis diagnosis NN cord-006870-f5w6fw6q 1005 48 / / SYM cord-006870-f5w6fw6q 1005 49 procedure procedure NN cord-006870-f5w6fw6q 1005 50 , , , cord-006870-f5w6fw6q 1005 51 estimated estimate VBN cord-006870-f5w6fw6q 1005 52 blood blood NN cord-006870-f5w6fw6q 1005 53 loss loss NN cord-006870-f5w6fw6q 1005 54 , , , cord-006870-f5w6fw6q 1005 55 blood blood NN cord-006870-f5w6fw6q 1005 56 / / SYM cord-006870-f5w6fw6q 1005 57 fluid fluid NN cord-006870-f5w6fw6q 1005 58 intake intake NN cord-006870-f5w6fw6q 1005 59 , , , cord-006870-f5w6fw6q 1005 60 airway airway NN cord-006870-f5w6fw6q 1005 61 concerns concern NNS cord-006870-f5w6fw6q 1005 62 , , , cord-006870-f5w6fw6q 1005 63 complications complication NNS cord-006870-f5w6fw6q 1005 64 and and CC cord-006870-f5w6fw6q 1005 65 overall overall JJ cord-006870-f5w6fw6q 1005 66 satisfaction satisfaction NN cord-006870-f5w6fw6q 1005 67 with with IN cord-006870-f5w6fw6q 1005 68 handoff handoff NN cord-006870-f5w6fw6q 1005 69 . . . cord-006870-f5w6fw6q 1006 1 A a DT cord-006870-f5w6fw6q 1006 2 taskforce taskforce NN cord-006870-f5w6fw6q 1006 3 of of IN cord-006870-f5w6fw6q 1006 4 RNs rn NNS cord-006870-f5w6fw6q 1006 5 , , , cord-006870-f5w6fw6q 1006 6 NPs NPs NNP cord-006870-f5w6fw6q 1006 7 , , , cord-006870-f5w6fw6q 1006 8 neurointensivists neurointensivists NNP cord-006870-f5w6fw6q 1006 9 , , , cord-006870-f5w6fw6q 1006 10 and and CC cord-006870-f5w6fw6q 1006 11 neurosurgeons neurosurgeon NNS cord-006870-f5w6fw6q 1006 12 was be VBD cord-006870-f5w6fw6q 1006 13 established establish VBN cord-006870-f5w6fw6q 1006 14 , , , cord-006870-f5w6fw6q 1006 15 ending end VBG cord-006870-f5w6fw6q 1006 16 with with IN cord-006870-f5w6fw6q 1006 17 the the DT cord-006870-f5w6fw6q 1006 18 creation creation NN cord-006870-f5w6fw6q 1006 19 of of IN cord-006870-f5w6fw6q 1006 20 a a DT cord-006870-f5w6fw6q 1006 21 handoff handoff NN cord-006870-f5w6fw6q 1006 22 tool tool NN cord-006870-f5w6fw6q 1006 23 and and CC cord-006870-f5w6fw6q 1006 24 timeout timeout NN cord-006870-f5w6fw6q 1006 25 process process NN cord-006870-f5w6fw6q 1006 26 . . . cord-006870-f5w6fw6q 1007 1 The the DT cord-006870-f5w6fw6q 1007 2 new new JJ cord-006870-f5w6fw6q 1007 3 tool tool NN cord-006870-f5w6fw6q 1007 4 and and CC cord-006870-f5w6fw6q 1007 5 process process NN cord-006870-f5w6fw6q 1007 6 were be VBD cord-006870-f5w6fw6q 1007 7 initiated initiate VBN cord-006870-f5w6fw6q 1007 8 and and CC cord-006870-f5w6fw6q 1007 9 two two CD cord-006870-f5w6fw6q 1007 10 months month NNS cord-006870-f5w6fw6q 1007 11 later later RB cord-006870-f5w6fw6q 1007 12 , , , cord-006870-f5w6fw6q 1007 13 a a DT cord-006870-f5w6fw6q 1007 14 repeat repeat NN cord-006870-f5w6fw6q 1007 15 survey survey NN cord-006870-f5w6fw6q 1007 16 was be VBD cord-006870-f5w6fw6q 1007 17 sent send VBN cord-006870-f5w6fw6q 1007 18 to to TO cord-006870-f5w6fw6q 1007 19 evaluate evaluate VB cord-006870-f5w6fw6q 1007 20 staff staff NN cord-006870-f5w6fw6q 1007 21 satisfaction satisfaction NN cord-006870-f5w6fw6q 1007 22 and and CC cord-006870-f5w6fw6q 1007 23 perceived perceive VBN cord-006870-f5w6fw6q 1007 24 effectiveness effectiveness NN cord-006870-f5w6fw6q 1007 25 of of IN cord-006870-f5w6fw6q 1007 26 the the DT cord-006870-f5w6fw6q 1007 27 new new JJ cord-006870-f5w6fw6q 1007 28 process process NN cord-006870-f5w6fw6q 1007 29 and and CC cord-006870-f5w6fw6q 1007 30 handoff handoff NN cord-006870-f5w6fw6q 1007 31 tool tool NN cord-006870-f5w6fw6q 1007 32 . . . cord-006870-f5w6fw6q 1008 1 Currently currently RB cord-006870-f5w6fw6q 1008 2 being be VBG cord-006870-f5w6fw6q 1008 3 tabulated tabulate VBN cord-006870-f5w6fw6q 1008 4 at at IN cord-006870-f5w6fw6q 1008 5 time time NN cord-006870-f5w6fw6q 1008 6 of of IN cord-006870-f5w6fw6q 1008 7 submission submission NN cord-006870-f5w6fw6q 1008 8 . . . cord-006870-f5w6fw6q 1009 1 Using use VBG cord-006870-f5w6fw6q 1009 2 standardized standardize VBN cord-006870-f5w6fw6q 1009 3 , , , cord-006870-f5w6fw6q 1009 4 open open JJ cord-006870-f5w6fw6q 1009 5 communication communication NN cord-006870-f5w6fw6q 1009 6 techniques technique NNS cord-006870-f5w6fw6q 1009 7 including include VBG cord-006870-f5w6fw6q 1009 8 handoff handoff NN cord-006870-f5w6fw6q 1009 9 tools tool NNS cord-006870-f5w6fw6q 1009 10 and and CC cord-006870-f5w6fw6q 1009 11 a a DT cord-006870-f5w6fw6q 1009 12 timeout timeout NN cord-006870-f5w6fw6q 1009 13 throughout throughout IN cord-006870-f5w6fw6q 1009 14 the the DT cord-006870-f5w6fw6q 1009 15 perioperative perioperative JJ cord-006870-f5w6fw6q 1009 16 period period NN cord-006870-f5w6fw6q 1009 17 is be VBZ cord-006870-f5w6fw6q 1009 18 crucial crucial JJ cord-006870-f5w6fw6q 1009 19 to to IN cord-006870-f5w6fw6q 1009 20 positive positive JJ cord-006870-f5w6fw6q 1009 21 outcomes outcome NNS cord-006870-f5w6fw6q 1009 22 and and CC cord-006870-f5w6fw6q 1009 23 can can MD cord-006870-f5w6fw6q 1009 24 improve improve VB cord-006870-f5w6fw6q 1009 25 perioperative perioperative JJ cord-006870-f5w6fw6q 1009 26 care care NN cord-006870-f5w6fw6q 1009 27 in in IN cord-006870-f5w6fw6q 1009 28 the the DT cord-006870-f5w6fw6q 1009 29 NCCU NCCU NNP cord-006870-f5w6fw6q 1009 30 patient patient NN cord-006870-f5w6fw6q 1009 31 and and CC cord-006870-f5w6fw6q 1009 32 increase increase VB cord-006870-f5w6fw6q 1009 33 satisfaction satisfaction NN cord-006870-f5w6fw6q 1009 34 and and CC cord-006870-f5w6fw6q 1009 35 collaboration collaboration NN cord-006870-f5w6fw6q 1009 36 of of IN cord-006870-f5w6fw6q 1009 37 all all DT cord-006870-f5w6fw6q 1009 38 team team NN cord-006870-f5w6fw6q 1009 39 member member NN cord-006870-f5w6fw6q 1009 40 during during IN cord-006870-f5w6fw6q 1009 41 OR or CC cord-006870-f5w6fw6q 1009 42 handoff handoff NN cord-006870-f5w6fw6q 1009 43 . . . cord-006870-f5w6fw6q 1010 1 In in IN cord-006870-f5w6fw6q 1010 2 the the DT cord-006870-f5w6fw6q 1010 3 age age NN cord-006870-f5w6fw6q 1010 4 of of IN cord-006870-f5w6fw6q 1010 5 the the DT cord-006870-f5w6fw6q 1010 6 Healthcare Healthcare NNP cord-006870-f5w6fw6q 1010 7 Reform Reform NNP cord-006870-f5w6fw6q 1010 8 and and CC cord-006870-f5w6fw6q 1010 9 rising rise VBG cord-006870-f5w6fw6q 1010 10 costs cost NNS cord-006870-f5w6fw6q 1010 11 , , , cord-006870-f5w6fw6q 1010 12 it -PRON- PRP cord-006870-f5w6fw6q 1010 13 is be VBZ cord-006870-f5w6fw6q 1010 14 important important JJ cord-006870-f5w6fw6q 1010 15 for for IN cord-006870-f5w6fw6q 1010 16 strategic strategic JJ cord-006870-f5w6fw6q 1010 17 service service NN cord-006870-f5w6fw6q 1010 18 lines line NNS cord-006870-f5w6fw6q 1010 19 to to TO cord-006870-f5w6fw6q 1010 20 explore explore VB cord-006870-f5w6fw6q 1010 21 cost cost NN cord-006870-f5w6fw6q 1010 22 saving saving NN cord-006870-f5w6fw6q 1010 23 and and CC cord-006870-f5w6fw6q 1010 24 care care VB cord-006870-f5w6fw6q 1010 25 efficiency efficiency NN cord-006870-f5w6fw6q 1010 26 strategies strategy NNS cord-006870-f5w6fw6q 1010 27 . . . cord-006870-f5w6fw6q 1011 1 Beginning begin VBG cord-006870-f5w6fw6q 1011 2 in in IN cord-006870-f5w6fw6q 1011 3 September September NNP cord-006870-f5w6fw6q 1011 4 2016 2016 CD cord-006870-f5w6fw6q 1011 5 , , , cord-006870-f5w6fw6q 1011 6 physician physician NN cord-006870-f5w6fw6q 1011 7 and and CC cord-006870-f5w6fw6q 1011 8 administrative administrative JJ cord-006870-f5w6fw6q 1011 9 leadership leadership NN cord-006870-f5w6fw6q 1011 10 within within IN cord-006870-f5w6fw6q 1011 11 the the DT cord-006870-f5w6fw6q 1011 12 Duke Duke NNP cord-006870-f5w6fw6q 1011 13 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 1011 14 intensive intensive JJ cord-006870-f5w6fw6q 1011 15 care care NN cord-006870-f5w6fw6q 1011 16 unit unit NN cord-006870-f5w6fw6q 1011 17 ( ( -LRB- cord-006870-f5w6fw6q 1011 18 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 1011 19 ) ) -RRB- cord-006870-f5w6fw6q 1011 20 began begin VBD cord-006870-f5w6fw6q 1011 21 investigating investigate VBG cord-006870-f5w6fw6q 1011 22 per per IN cord-006870-f5w6fw6q 1011 23 patient patient JJ cord-006870-f5w6fw6q 1011 24 cost cost NN cord-006870-f5w6fw6q 1011 25 to to TO cord-006870-f5w6fw6q 1011 26 explore explore VB cord-006870-f5w6fw6q 1011 27 opportunities opportunity NNS cord-006870-f5w6fw6q 1011 28 to to TO cord-006870-f5w6fw6q 1011 29 decrease decrease VB cord-006870-f5w6fw6q 1011 30 direct direct JJ cord-006870-f5w6fw6q 1011 31 cost cost NN cord-006870-f5w6fw6q 1011 32 to to IN cord-006870-f5w6fw6q 1011 33 the the DT cord-006870-f5w6fw6q 1011 34 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 1011 35 , , , cord-006870-f5w6fw6q 1011 36 cost cost VBN cord-006870-f5w6fw6q 1011 37 to to IN cord-006870-f5w6fw6q 1011 38 the the DT cord-006870-f5w6fw6q 1011 39 patient patient NN cord-006870-f5w6fw6q 1011 40 , , , cord-006870-f5w6fw6q 1011 41 and and CC cord-006870-f5w6fw6q 1011 42 reduce reduce VB cord-006870-f5w6fw6q 1011 43 redundancy redundancy NN cord-006870-f5w6fw6q 1011 44 of of IN cord-006870-f5w6fw6q 1011 45 care care NN cord-006870-f5w6fw6q 1011 46 . . . cord-006870-f5w6fw6q 1012 1 With with IN cord-006870-f5w6fw6q 1012 2 assistance assistance NN cord-006870-f5w6fw6q 1012 3 from from IN cord-006870-f5w6fw6q 1012 4 Health Health NNP cord-006870-f5w6fw6q 1012 5 System System NNP cord-006870-f5w6fw6q 1012 6 Finance Finance NNP cord-006870-f5w6fw6q 1012 7 , , , cord-006870-f5w6fw6q 1012 8 the the DT cord-006870-f5w6fw6q 1012 9 team team NN cord-006870-f5w6fw6q 1012 10 assessed assess VBD cord-006870-f5w6fw6q 1012 11 the the DT cord-006870-f5w6fw6q 1012 12 following follow VBG cord-006870-f5w6fw6q 1012 13 data data NN cord-006870-f5w6fw6q 1012 14 points point NNS cord-006870-f5w6fw6q 1012 15 within within IN cord-006870-f5w6fw6q 1012 16 each each DT cord-006870-f5w6fw6q 1012 17 cost cost NN cord-006870-f5w6fw6q 1012 18 group group NN cord-006870-f5w6fw6q 1012 19 and and CC cord-006870-f5w6fw6q 1012 20 compared compare VBD cord-006870-f5w6fw6q 1012 21 these these DT cord-006870-f5w6fw6q 1012 22 values value NNS cord-006870-f5w6fw6q 1012 23 to to IN cord-006870-f5w6fw6q 1012 24 that that DT cord-006870-f5w6fw6q 1012 25 of of IN cord-006870-f5w6fw6q 1012 26 our -PRON- PRP$ cord-006870-f5w6fw6q 1012 27 peers peer NNS cord-006870-f5w6fw6q 1012 28 within within IN cord-006870-f5w6fw6q 1012 29 the the DT cord-006870-f5w6fw6q 1012 30 US US NNP cord-006870-f5w6fw6q 1012 31 News News NNP cord-006870-f5w6fw6q 1012 32 and and CC cord-006870-f5w6fw6q 1012 33 World World NNP cord-006870-f5w6fw6q 1012 34 Report Report NNP cord-006870-f5w6fw6q 1012 35 Top Top NNP cord-006870-f5w6fw6q 1012 36 Honor Honor NNP cord-006870-f5w6fw6q 1012 37 Roll roll NN cord-006870-f5w6fw6q 1012 38 : : : cord-006870-f5w6fw6q 1013 1 · · NFP cord-006870-f5w6fw6q 1013 2 Number number NN cord-006870-f5w6fw6q 1013 3 of of IN cord-006870-f5w6fw6q 1013 4 Units Units NNPS cord-006870-f5w6fw6q 1013 5 · · NFP cord-006870-f5w6fw6q 1013 6 Direct direct JJ cord-006870-f5w6fw6q 1013 7 Cost cost NN cord-006870-f5w6fw6q 1013 8 per per IN cord-006870-f5w6fw6q 1013 9 Unit unit NN cord-006870-f5w6fw6q 1013 10 · · NFP cord-006870-f5w6fw6q 1013 11 Total total VB cord-006870-f5w6fw6q 1013 12 Direct direct JJ cord-006870-f5w6fw6q 1013 13 Cost cost NN cord-006870-f5w6fw6q 1013 14 Our -PRON- PRP$ cord-006870-f5w6fw6q 1013 15 performance performance NN cord-006870-f5w6fw6q 1013 16 according accord VBG cord-006870-f5w6fw6q 1013 17 to to IN cord-006870-f5w6fw6q 1013 18 our -PRON- PRP$ cord-006870-f5w6fw6q 1013 19 peers peer NNS cord-006870-f5w6fw6q 1013 20 in in IN cord-006870-f5w6fw6q 1013 21 the the DT cord-006870-f5w6fw6q 1013 22 following follow VBG cord-006870-f5w6fw6q 1013 23 cost cost NN cord-006870-f5w6fw6q 1013 24 areas area NNS cord-006870-f5w6fw6q 1013 25 was be VBD cord-006870-f5w6fw6q 1013 26 : : : cord-006870-f5w6fw6q 1013 27 1.Pharmacy 1.pharmacy CD cord-006870-f5w6fw6q 1013 28 - - HYPH cord-006870-f5w6fw6q 1013 29 ranked rank VBN cord-006870-f5w6fw6q 1013 30 8th 8th NN cord-006870-f5w6fw6q 1013 31 out out IN cord-006870-f5w6fw6q 1013 32 of of IN cord-006870-f5w6fw6q 1013 33 15 15 CD cord-006870-f5w6fw6q 1013 34 2.Laboratories 2.laboratories CD cord-006870-f5w6fw6q 1013 35 - - HYPH cord-006870-f5w6fw6q 1013 36 ranked rank VBN cord-006870-f5w6fw6q 1013 37 12th 12th NN cord-006870-f5w6fw6q 1013 38 out out IN cord-006870-f5w6fw6q 1013 39 of of IN cord-006870-f5w6fw6q 1013 40 15 15 CD cord-006870-f5w6fw6q 1013 41 3.Radiology 3.radiology CD cord-006870-f5w6fw6q 1013 42 - - HYPH cord-006870-f5w6fw6q 1013 43 ranked rank VBN cord-006870-f5w6fw6q 1013 44 14th 14th RB cord-006870-f5w6fw6q 1013 45 out out IN cord-006870-f5w6fw6q 1013 46 of of IN cord-006870-f5w6fw6q 1013 47 15 15 CD cord-006870-f5w6fw6q 1013 48 4.Cardiovascular 4.cardiovascular CD cord-006870-f5w6fw6q 1013 49 - - HYPH cord-006870-f5w6fw6q 1013 50 ranked rank VBN cord-006870-f5w6fw6q 1013 51 14th 14th NN cord-006870-f5w6fw6q 1013 52 out out IN cord-006870-f5w6fw6q 1013 53 of of IN cord-006870-f5w6fw6q 1013 54 15 15 CD cord-006870-f5w6fw6q 1013 55 . . . cord-006870-f5w6fw6q 1014 1 Based base VBN cord-006870-f5w6fw6q 1014 2 on on IN cord-006870-f5w6fw6q 1014 3 these these DT cord-006870-f5w6fw6q 1014 4 performance performance NN cord-006870-f5w6fw6q 1014 5 metrics metric NNS cord-006870-f5w6fw6q 1014 6 , , , cord-006870-f5w6fw6q 1014 7 Neuroscience Neuroscience NNP cord-006870-f5w6fw6q 1014 8 administrative administrative JJ cord-006870-f5w6fw6q 1014 9 and and CC cord-006870-f5w6fw6q 1014 10 medical medical JJ cord-006870-f5w6fw6q 1014 11 leadership leadership NN cord-006870-f5w6fw6q 1014 12 developed develop VBD cord-006870-f5w6fw6q 1014 13 a a DT cord-006870-f5w6fw6q 1014 14 project project NN cord-006870-f5w6fw6q 1014 15 grid grid NN cord-006870-f5w6fw6q 1014 16 of of IN cord-006870-f5w6fw6q 1014 17 prospective prospective JJ cord-006870-f5w6fw6q 1014 18 initiatives initiative NNS cord-006870-f5w6fw6q 1014 19 and and CC cord-006870-f5w6fw6q 1014 20 identified identify VBD cord-006870-f5w6fw6q 1014 21 the the DT cord-006870-f5w6fw6q 1014 22 following follow VBG cord-006870-f5w6fw6q 1014 23 for for IN cord-006870-f5w6fw6q 1014 24 each each DT cord-006870-f5w6fw6q 1014 25 cost cost NN cord-006870-f5w6fw6q 1014 26 area area NN cord-006870-f5w6fw6q 1014 27 : : : cord-006870-f5w6fw6q 1014 28 · · NFP cord-006870-f5w6fw6q 1014 29 Stakeholder Stakeholder NNP cord-006870-f5w6fw6q 1014 30 - - HYPH cord-006870-f5w6fw6q 1014 31 led lead VBN cord-006870-f5w6fw6q 1014 32 teams team NNS cord-006870-f5w6fw6q 1014 33 inclusive inclusive JJ cord-006870-f5w6fw6q 1014 34 of of IN cord-006870-f5w6fw6q 1014 35 providers provider NNS cord-006870-f5w6fw6q 1014 36 , , , cord-006870-f5w6fw6q 1014 37 nursing nursing NN cord-006870-f5w6fw6q 1014 38 , , , cord-006870-f5w6fw6q 1014 39 and and CC cord-006870-f5w6fw6q 1014 40 administration administration NN cord-006870-f5w6fw6q 1014 41 · · NFP cord-006870-f5w6fw6q 1014 42 Duration duration NN cord-006870-f5w6fw6q 1014 43 or or CC cord-006870-f5w6fw6q 1014 44 impact impact NN cord-006870-f5w6fw6q 1014 45 of of IN cord-006870-f5w6fw6q 1014 46 each each DT cord-006870-f5w6fw6q 1014 47 initiative initiative NN cord-006870-f5w6fw6q 1014 48 : : : cord-006870-f5w6fw6q 1014 49 short short JJ cord-006870-f5w6fw6q 1014 50 , , , cord-006870-f5w6fw6q 1014 51 medium medium NN cord-006870-f5w6fw6q 1014 52 , , , cord-006870-f5w6fw6q 1014 53 or or CC cord-006870-f5w6fw6q 1014 54 long long JJ cord-006870-f5w6fw6q 1014 55 · · NFP cord-006870-f5w6fw6q 1014 56 Activity activity NN cord-006870-f5w6fw6q 1014 57 phases phase NNS cord-006870-f5w6fw6q 1014 58 based base VBN cord-006870-f5w6fw6q 1014 59 on on IN cord-006870-f5w6fw6q 1014 60 duration duration NN cord-006870-f5w6fw6q 1014 61 The the DT cord-006870-f5w6fw6q 1014 62 stakeholder stakeholder NN cord-006870-f5w6fw6q 1014 63 - - HYPH cord-006870-f5w6fw6q 1014 64 led lead VBN cord-006870-f5w6fw6q 1014 65 groups group NNS cord-006870-f5w6fw6q 1014 66 would would MD cord-006870-f5w6fw6q 1014 67 propose propose VB cord-006870-f5w6fw6q 1014 68 and and CC cord-006870-f5w6fw6q 1014 69 validate validate VB cord-006870-f5w6fw6q 1014 70 projects project NNS cord-006870-f5w6fw6q 1014 71 based base VBN cord-006870-f5w6fw6q 1014 72 on on IN cord-006870-f5w6fw6q 1014 73 scope scope NN cord-006870-f5w6fw6q 1014 74 and and CC cord-006870-f5w6fw6q 1014 75 duration duration NN cord-006870-f5w6fw6q 1014 76 . . . cord-006870-f5w6fw6q 1015 1 At at IN cord-006870-f5w6fw6q 1015 2 each each DT cord-006870-f5w6fw6q 1015 3 group group NN cord-006870-f5w6fw6q 1015 4 's 's POS cord-006870-f5w6fw6q 1015 5 meeting meeting NN cord-006870-f5w6fw6q 1015 6 , , , cord-006870-f5w6fw6q 1015 7 members member NNS cord-006870-f5w6fw6q 1015 8 reviewed review VBD cord-006870-f5w6fw6q 1015 9 charge charge NN cord-006870-f5w6fw6q 1015 10 level level NN cord-006870-f5w6fw6q 1015 11 financial financial JJ cord-006870-f5w6fw6q 1015 12 data datum NNS cord-006870-f5w6fw6q 1015 13 by by IN cord-006870-f5w6fw6q 1015 14 activity activity NN cord-006870-f5w6fw6q 1015 15 code code NN cord-006870-f5w6fw6q 1015 16 for for IN cord-006870-f5w6fw6q 1015 17 the the DT cord-006870-f5w6fw6q 1015 18 group group NN cord-006870-f5w6fw6q 1015 19 's 's POS cord-006870-f5w6fw6q 1015 20 respective respective JJ cord-006870-f5w6fw6q 1015 21 cost cost NN cord-006870-f5w6fw6q 1015 22 area area NN cord-006870-f5w6fw6q 1015 23 to to TO cord-006870-f5w6fw6q 1015 24 develop develop VB cord-006870-f5w6fw6q 1015 25 applicable applicable JJ cord-006870-f5w6fw6q 1015 26 initiatives initiative NNS cord-006870-f5w6fw6q 1015 27 . . . cord-006870-f5w6fw6q 1016 1 Multiple multiple JJ cord-006870-f5w6fw6q 1016 2 initiatives initiative NNS cord-006870-f5w6fw6q 1016 3 are be VBP cord-006870-f5w6fw6q 1016 4 currently currently RB cord-006870-f5w6fw6q 1016 5 underway underway JJ cord-006870-f5w6fw6q 1016 6 including include VBG cord-006870-f5w6fw6q 1016 7 those those DT cord-006870-f5w6fw6q 1016 8 within within IN cord-006870-f5w6fw6q 1016 9 the the DT cord-006870-f5w6fw6q 1016 10 cost cost NN cord-006870-f5w6fw6q 1016 11 areas area NNS cord-006870-f5w6fw6q 1016 12 of of IN cord-006870-f5w6fw6q 1016 13 Pharmacy Pharmacy NNP cord-006870-f5w6fw6q 1016 14 , , , cord-006870-f5w6fw6q 1016 15 Laboratories Laboratories NNPS cord-006870-f5w6fw6q 1016 16 , , , cord-006870-f5w6fw6q 1016 17 and and CC cord-006870-f5w6fw6q 1016 18 Radiology Radiology NNP cord-006870-f5w6fw6q 1016 19 . . . cord-006870-f5w6fw6q 1017 1 Included include VBN cord-006870-f5w6fw6q 1017 2 among among IN cord-006870-f5w6fw6q 1017 3 these these DT cord-006870-f5w6fw6q 1017 4 initiatives initiative NNS cord-006870-f5w6fw6q 1017 5 is be VBZ cord-006870-f5w6fw6q 1017 6 a a DT cord-006870-f5w6fw6q 1017 7 change change NN cord-006870-f5w6fw6q 1017 8 in in IN cord-006870-f5w6fw6q 1017 9 routine routine JJ cord-006870-f5w6fw6q 1017 10 resistant resistant JJ cord-006870-f5w6fw6q 1017 11 organism organism NN cord-006870-f5w6fw6q 1017 12 screening screening NN cord-006870-f5w6fw6q 1017 13 and and CC cord-006870-f5w6fw6q 1017 14 cervical cervical JJ cord-006870-f5w6fw6q 1017 15 spine spine NN cord-006870-f5w6fw6q 1017 16 clearance clearance NN cord-006870-f5w6fw6q 1017 17 . . . cord-006870-f5w6fw6q 1018 1 Other other JJ cord-006870-f5w6fw6q 1018 2 initiatives initiative NNS cord-006870-f5w6fw6q 1018 3 will will MD cord-006870-f5w6fw6q 1018 4 be be VB cord-006870-f5w6fw6q 1018 5 target target VB cord-006870-f5w6fw6q 1018 6 intravenous intravenous JJ cord-006870-f5w6fw6q 1018 7 anti anti JJ cord-006870-f5w6fw6q 1018 8 - - JJ cord-006870-f5w6fw6q 1018 9 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1018 10 treatment treatment NN cord-006870-f5w6fw6q 1018 11 and and CC cord-006870-f5w6fw6q 1018 12 laboratory laboratory NN cord-006870-f5w6fw6q 1018 13 frequency frequency NN cord-006870-f5w6fw6q 1018 14 . . . cord-006870-f5w6fw6q 1019 1 The the DT cord-006870-f5w6fw6q 1019 2 total total JJ cord-006870-f5w6fw6q 1019 3 cost cost NN cord-006870-f5w6fw6q 1019 4 savings saving NNS cord-006870-f5w6fw6q 1019 5 from from IN cord-006870-f5w6fw6q 1019 6 these these DT cord-006870-f5w6fw6q 1019 7 initiatives initiative NNS cord-006870-f5w6fw6q 1019 8 can can MD cord-006870-f5w6fw6q 1019 9 only only RB cord-006870-f5w6fw6q 1019 10 be be VB cord-006870-f5w6fw6q 1019 11 estimated estimate VBN cord-006870-f5w6fw6q 1019 12 at at IN cord-006870-f5w6fw6q 1019 13 this this DT cord-006870-f5w6fw6q 1019 14 point point NN cord-006870-f5w6fw6q 1019 15 but but CC cord-006870-f5w6fw6q 1019 16 will will MD cord-006870-f5w6fw6q 1019 17 likely likely RB cord-006870-f5w6fw6q 1019 18 be be VB cord-006870-f5w6fw6q 1019 19 in in IN cord-006870-f5w6fw6q 1019 20 excess excess NN cord-006870-f5w6fw6q 1019 21 of of IN cord-006870-f5w6fw6q 1019 22 $ $ $ cord-006870-f5w6fw6q 1019 23 50,000 50,000 CD cord-006870-f5w6fw6q 1019 24 for for IN cord-006870-f5w6fw6q 1019 25 the the DT cord-006870-f5w6fw6q 1019 26 calendar calendar NN cord-006870-f5w6fw6q 1019 27 year year NN cord-006870-f5w6fw6q 1019 28 . . . cord-006870-f5w6fw6q 1020 1 It -PRON- PRP cord-006870-f5w6fw6q 1020 2 is be VBZ cord-006870-f5w6fw6q 1020 3 uncertain uncertain JJ cord-006870-f5w6fw6q 1020 4 whether whether IN cord-006870-f5w6fw6q 1020 5 dedicated dedicated JJ cord-006870-f5w6fw6q 1020 6 neurocritical neurocritical JJ cord-006870-f5w6fw6q 1020 7 care care NN cord-006870-f5w6fw6q 1020 8 units unit NNS cord-006870-f5w6fw6q 1020 9 are be VBP cord-006870-f5w6fw6q 1020 10 associated associate VBN cord-006870-f5w6fw6q 1020 11 with with IN cord-006870-f5w6fw6q 1020 12 improved improved JJ cord-006870-f5w6fw6q 1020 13 outcomes outcome NNS cord-006870-f5w6fw6q 1020 14 for for IN cord-006870-f5w6fw6q 1020 15 critically critically RB cord-006870-f5w6fw6q 1020 16 ill ill RB cord-006870-f5w6fw6q 1020 17 neurologically neurologically RB cord-006870-f5w6fw6q 1020 18 injured injured JJ cord-006870-f5w6fw6q 1020 19 patients patient NNS cord-006870-f5w6fw6q 1020 20 in in IN cord-006870-f5w6fw6q 1020 21 the the DT cord-006870-f5w6fw6q 1020 22 era era NN cord-006870-f5w6fw6q 1020 23 of of IN cord-006870-f5w6fw6q 1020 24 collaborative collaborative JJ cord-006870-f5w6fw6q 1020 25 protocol protocol NN cord-006870-f5w6fw6q 1020 26 - - HYPH cord-006870-f5w6fw6q 1020 27 driven drive VBN cord-006870-f5w6fw6q 1020 28 care care NN cord-006870-f5w6fw6q 1020 29 . . . cord-006870-f5w6fw6q 1021 1 We -PRON- PRP cord-006870-f5w6fw6q 1021 2 examined examine VBD cord-006870-f5w6fw6q 1021 3 the the DT cord-006870-f5w6fw6q 1021 4 association association NN cord-006870-f5w6fw6q 1021 5 between between IN cord-006870-f5w6fw6q 1021 6 dedicated dedicated NNP cord-006870-f5w6fw6q 1021 7 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1021 8 care care NN cord-006870-f5w6fw6q 1021 9 units unit NNS cord-006870-f5w6fw6q 1021 10 and and CC cord-006870-f5w6fw6q 1021 11 mortality mortality NN cord-006870-f5w6fw6q 1021 12 , , , cord-006870-f5w6fw6q 1021 13 and and CC cord-006870-f5w6fw6q 1021 14 the the DT cord-006870-f5w6fw6q 1021 15 effects effect NNS cord-006870-f5w6fw6q 1021 16 of of IN cord-006870-f5w6fw6q 1021 17 standardized standardized JJ cord-006870-f5w6fw6q 1021 18 management management NN cord-006870-f5w6fw6q 1021 19 protocols protocol NNS cord-006870-f5w6fw6q 1021 20 for for IN cord-006870-f5w6fw6q 1021 21 severe severe JJ cord-006870-f5w6fw6q 1021 22 traumatic traumatic JJ cord-006870-f5w6fw6q 1021 23 brain brain NN cord-006870-f5w6fw6q 1021 24 injury injury NN cord-006870-f5w6fw6q 1021 25 . . . cord-006870-f5w6fw6q 1022 1 We -PRON- PRP cord-006870-f5w6fw6q 1022 2 surveyed survey VBD cord-006870-f5w6fw6q 1022 3 trauma trauma NN cord-006870-f5w6fw6q 1022 4 medical medical JJ cord-006870-f5w6fw6q 1022 5 directors director NNS cord-006870-f5w6fw6q 1022 6 from from IN cord-006870-f5w6fw6q 1022 7 centers center NNS cord-006870-f5w6fw6q 1022 8 participating participate VBG cord-006870-f5w6fw6q 1022 9 in in IN cord-006870-f5w6fw6q 1022 10 the the DT cord-006870-f5w6fw6q 1022 11 American American NNP cord-006870-f5w6fw6q 1022 12 College College NNP cord-006870-f5w6fw6q 1022 13 of of IN cord-006870-f5w6fw6q 1022 14 Surgeons Surgeons NNPS cord-006870-f5w6fw6q 1022 15 Trauma Trauma NNP cord-006870-f5w6fw6q 1022 16 Quality Quality NNP cord-006870-f5w6fw6q 1022 17 Improvement Improvement NNP cord-006870-f5w6fw6q 1022 18 Program Program NNP cord-006870-f5w6fw6q 1022 19 ( ( -LRB- cord-006870-f5w6fw6q 1022 20 TQIP TQIP NNP cord-006870-f5w6fw6q 1022 21 ) ) -RRB- cord-006870-f5w6fw6q 1022 22 to to TO cord-006870-f5w6fw6q 1022 23 obtain obtain VB cord-006870-f5w6fw6q 1022 24 information information NN cord-006870-f5w6fw6q 1022 25 about about IN cord-006870-f5w6fw6q 1022 26 ICU ICU NNP cord-006870-f5w6fw6q 1022 27 structure structure NN cord-006870-f5w6fw6q 1022 28 and and CC cord-006870-f5w6fw6q 1022 29 processes process NNS cord-006870-f5w6fw6q 1022 30 of of IN cord-006870-f5w6fw6q 1022 31 care care NN cord-006870-f5w6fw6q 1022 32 . . . cord-006870-f5w6fw6q 1023 1 Survey survey NN cord-006870-f5w6fw6q 1023 2 data datum NNS cord-006870-f5w6fw6q 1023 3 were be VBD cord-006870-f5w6fw6q 1023 4 then then RB cord-006870-f5w6fw6q 1023 5 linked link VBN cord-006870-f5w6fw6q 1023 6 to to IN cord-006870-f5w6fw6q 1023 7 the the DT cord-006870-f5w6fw6q 1023 8 TQIP TQIP NNP cord-006870-f5w6fw6q 1023 9 registry registry NN cord-006870-f5w6fw6q 1023 10 , , , cord-006870-f5w6fw6q 1023 11 and and CC cord-006870-f5w6fw6q 1023 12 random random JJ cord-006870-f5w6fw6q 1023 13 - - HYPH cord-006870-f5w6fw6q 1023 14 intercept intercept VB cord-006870-f5w6fw6q 1023 15 hierarchical hierarchical JJ cord-006870-f5w6fw6q 1023 16 multivariable multivariable JJ cord-006870-f5w6fw6q 1023 17 modeling modeling NN cord-006870-f5w6fw6q 1023 18 was be VBD cord-006870-f5w6fw6q 1023 19 used use VBN cord-006870-f5w6fw6q 1023 20 to to TO cord-006870-f5w6fw6q 1023 21 evaluate evaluate VB cord-006870-f5w6fw6q 1023 22 the the DT cord-006870-f5w6fw6q 1023 23 association association NN cord-006870-f5w6fw6q 1023 24 between between IN cord-006870-f5w6fw6q 1023 25 dedicated dedicated NNP cord-006870-f5w6fw6q 1023 26 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1023 27 care care NN cord-006870-f5w6fw6q 1023 28 ( ( -LRB- cord-006870-f5w6fw6q 1023 29 NCC NCC NNP cord-006870-f5w6fw6q 1023 30 ) ) -RRB- cord-006870-f5w6fw6q 1023 31 units unit NNS cord-006870-f5w6fw6q 1023 32 , , , cord-006870-f5w6fw6q 1023 33 the the DT cord-006870-f5w6fw6q 1023 34 presence presence NN cord-006870-f5w6fw6q 1023 35 of of IN cord-006870-f5w6fw6q 1023 36 standardized standardized JJ cord-006870-f5w6fw6q 1023 37 management management NN cord-006870-f5w6fw6q 1023 38 protocols protocol NNS cord-006870-f5w6fw6q 1023 39 and and CC cord-006870-f5w6fw6q 1023 40 mortality mortality NN cord-006870-f5w6fw6q 1023 41 . . . cord-006870-f5w6fw6q 1024 1 We -PRON- PRP cord-006870-f5w6fw6q 1024 2 performed perform VBD cord-006870-f5w6fw6q 1024 3 three three CD cord-006870-f5w6fw6q 1024 4 sensitivity sensitivity NN cord-006870-f5w6fw6q 1024 5 analyses analysis NNS cord-006870-f5w6fw6q 1024 6 reclassifying reclassify VBG cord-006870-f5w6fw6q 1024 7 NCC NCC NNP cord-006870-f5w6fw6q 1024 8 units unit NNS cord-006870-f5w6fw6q 1024 9 by by IN cord-006870-f5w6fw6q 1024 10 restricting restrict VBG cord-006870-f5w6fw6q 1024 11 to to IN cord-006870-f5w6fw6q 1024 12 closed closed JJ cord-006870-f5w6fw6q 1024 13 units unit NNS cord-006870-f5w6fw6q 1024 14 , , , cord-006870-f5w6fw6q 1024 15 under under IN cord-006870-f5w6fw6q 1024 16 UCNS UCNS NNP cord-006870-f5w6fw6q 1024 17 director director NN cord-006870-f5w6fw6q 1024 18 leadership leadership NN cord-006870-f5w6fw6q 1024 19 , , , cord-006870-f5w6fw6q 1024 20 and and CC cord-006870-f5w6fw6q 1024 21 exclusion exclusion NN cord-006870-f5w6fw6q 1024 22 of of IN cord-006870-f5w6fw6q 1024 23 neurotrauma neurotrauma NNP cord-006870-f5w6fw6q 1024 24 units unit NNS cord-006870-f5w6fw6q 1024 25 . . . cord-006870-f5w6fw6q 1025 1 Data datum NNS cord-006870-f5w6fw6q 1025 2 was be VBD cord-006870-f5w6fw6q 1025 3 analyzed analyze VBN cord-006870-f5w6fw6q 1025 4 from from IN cord-006870-f5w6fw6q 1025 5 9,773 9,773 CD cord-006870-f5w6fw6q 1025 6 adult adult NN cord-006870-f5w6fw6q 1025 7 patients patient NNS cord-006870-f5w6fw6q 1025 8 with with IN cord-006870-f5w6fw6q 1025 9 isolated isolate VBN cord-006870-f5w6fw6q 1025 10 severe severe JJ cord-006870-f5w6fw6q 1025 11 traumatic traumatic JJ cord-006870-f5w6fw6q 1025 12 brain brain NN cord-006870-f5w6fw6q 1025 13 injury injury NN cord-006870-f5w6fw6q 1025 14 admitted admit VBN cord-006870-f5w6fw6q 1025 15 to to IN cord-006870-f5w6fw6q 1025 16 134 134 CD cord-006870-f5w6fw6q 1025 17 TQIP TQIP NNP cord-006870-f5w6fw6q 1025 18 centers center NNS cord-006870-f5w6fw6q 1025 19 between between IN cord-006870-f5w6fw6q 1025 20 2011 2011 CD cord-006870-f5w6fw6q 1025 21 to to IN cord-006870-f5w6fw6q 1025 22 2013 2013 CD cord-006870-f5w6fw6q 1025 23 . . . cord-006870-f5w6fw6q 1026 1 Fifty fifty CD cord-006870-f5w6fw6q 1026 2 ICUs icu NNS cord-006870-f5w6fw6q 1026 3 were be VBD cord-006870-f5w6fw6q 1026 4 dedicated dedicated JJ cord-006870-f5w6fw6q 1026 5 neurocritical neurocritical JJ cord-006870-f5w6fw6q 1026 6 care care NN cord-006870-f5w6fw6q 1026 7 units unit NNS cord-006870-f5w6fw6q 1026 8 , , , cord-006870-f5w6fw6q 1026 9 whereas whereas IN cord-006870-f5w6fw6q 1026 10 84 84 CD cord-006870-f5w6fw6q 1026 11 were be VBD cord-006870-f5w6fw6q 1026 12 general general JJ cord-006870-f5w6fw6q 1026 13 ICUs ICUs NNP cord-006870-f5w6fw6q 1026 14 . . . cord-006870-f5w6fw6q 1027 1 Rates rate NNS cord-006870-f5w6fw6q 1027 2 of of IN cord-006870-f5w6fw6q 1027 3 standardized standardized JJ cord-006870-f5w6fw6q 1027 4 management management NN cord-006870-f5w6fw6q 1027 5 protocols protocol NNS cord-006870-f5w6fw6q 1027 6 were be VBD cord-006870-f5w6fw6q 1027 7 similar similar JJ cord-006870-f5w6fw6q 1027 8 comparing compare VBG cord-006870-f5w6fw6q 1027 9 dedicated dedicated JJ cord-006870-f5w6fw6q 1027 10 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1027 11 care care NN cord-006870-f5w6fw6q 1027 12 units unit NNS cord-006870-f5w6fw6q 1027 13 and and CC cord-006870-f5w6fw6q 1027 14 general general JJ cord-006870-f5w6fw6q 1027 15 ICUs ICUs NNP cord-006870-f5w6fw6q 1027 16 . . . cord-006870-f5w6fw6q 1028 1 Care care VB cord-006870-f5w6fw6q 1028 2 in in IN cord-006870-f5w6fw6q 1028 3 a a DT cord-006870-f5w6fw6q 1028 4 dedicated dedicated JJ cord-006870-f5w6fw6q 1028 5 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1028 6 care care NN cord-006870-f5w6fw6q 1028 7 unit unit NN cord-006870-f5w6fw6q 1028 8 was be VBD cord-006870-f5w6fw6q 1028 9 not not RB cord-006870-f5w6fw6q 1028 10 associated associate VBN cord-006870-f5w6fw6q 1028 11 with with IN cord-006870-f5w6fw6q 1028 12 improved improved JJ cord-006870-f5w6fw6q 1028 13 risk risk NN cord-006870-f5w6fw6q 1028 14 - - HYPH cord-006870-f5w6fw6q 1028 15 adjusted adjust VBN cord-006870-f5w6fw6q 1028 16 in in IN cord-006870-f5w6fw6q 1028 17 - - HYPH cord-006870-f5w6fw6q 1028 18 hospital hospital NN cord-006870-f5w6fw6q 1028 19 survival survival NN cord-006870-f5w6fw6q 1028 20 ( ( -LRB- cord-006870-f5w6fw6q 1028 21 OR or NN cord-006870-f5w6fw6q 1028 22 0.97 0.97 CD cord-006870-f5w6fw6q 1028 23 ; ; . cord-006870-f5w6fw6q 1029 1 ( ( -LRB- cord-006870-f5w6fw6q 1029 2 95 95 CD cord-006870-f5w6fw6q 1029 3 % % NN cord-006870-f5w6fw6q 1029 4 CI CI NNP cord-006870-f5w6fw6q 1029 5 0.80 0.80 CD cord-006870-f5w6fw6q 1029 6 - - HYPH cord-006870-f5w6fw6q 1029 7 1.19 1.19 CD cord-006870-f5w6fw6q 1029 8 ; ; : cord-006870-f5w6fw6q 1029 9 P= p= NN cord-006870-f5w6fw6q 1029 10 0.79 0.79 CD cord-006870-f5w6fw6q 1029 11 ) ) -RRB- cord-006870-f5w6fw6q 1029 12 . . . cord-006870-f5w6fw6q 1030 1 The the DT cord-006870-f5w6fw6q 1030 2 results result NNS cord-006870-f5w6fw6q 1030 3 from from IN cord-006870-f5w6fw6q 1030 4 the the DT cord-006870-f5w6fw6q 1030 5 model model NN cord-006870-f5w6fw6q 1030 6 were be VBD cord-006870-f5w6fw6q 1030 7 robust robust JJ cord-006870-f5w6fw6q 1030 8 in in IN cord-006870-f5w6fw6q 1030 9 our -PRON- PRP$ cord-006870-f5w6fw6q 1030 10 sensitivity sensitivity NN cord-006870-f5w6fw6q 1030 11 analyses analysis NNS cord-006870-f5w6fw6q 1030 12 . . . cord-006870-f5w6fw6q 1031 1 The the DT cord-006870-f5w6fw6q 1031 2 presence presence NN cord-006870-f5w6fw6q 1031 3 of of IN cord-006870-f5w6fw6q 1031 4 a a DT cord-006870-f5w6fw6q 1031 5 standardized standardized JJ cord-006870-f5w6fw6q 1031 6 management management NN cord-006870-f5w6fw6q 1031 7 protocol protocol NN cord-006870-f5w6fw6q 1031 8 for for IN cord-006870-f5w6fw6q 1031 9 these these DT cord-006870-f5w6fw6q 1031 10 patients patient NNS cord-006870-f5w6fw6q 1031 11 was be VBD cord-006870-f5w6fw6q 1031 12 associated associate VBN cord-006870-f5w6fw6q 1031 13 with with IN cord-006870-f5w6fw6q 1031 14 lower low JJR cord-006870-f5w6fw6q 1031 15 risk risk NN cord-006870-f5w6fw6q 1031 16 - - HYPH cord-006870-f5w6fw6q 1031 17 adjusted adjust VBN cord-006870-f5w6fw6q 1031 18 in in IN cord-006870-f5w6fw6q 1031 19 - - HYPH cord-006870-f5w6fw6q 1031 20 hospital hospital NN cord-006870-f5w6fw6q 1031 21 mortality mortality NN cord-006870-f5w6fw6q 1031 22 ( ( -LRB- cord-006870-f5w6fw6q 1031 23 OR or CC cord-006870-f5w6fw6q 1031 24 0.77 0.77 CD cord-006870-f5w6fw6q 1031 25 ; ; : cord-006870-f5w6fw6q 1031 26 95 95 CD cord-006870-f5w6fw6q 1031 27 % % NN cord-006870-f5w6fw6q 1031 28 CI CI NNP cord-006870-f5w6fw6q 1031 29 0.63 0.63 CD cord-006870-f5w6fw6q 1031 30 - - HYPH cord-006870-f5w6fw6q 1031 31 0.93 0.93 CD cord-006870-f5w6fw6q 1031 32 ; ; : cord-006870-f5w6fw6q 1031 33 P=0.009 p=0.009 NN cord-006870-f5w6fw6q 1031 34 ) ) -RRB- cord-006870-f5w6fw6q 1031 35 . . . cord-006870-f5w6fw6q 1032 1 Compared compare VBN cord-006870-f5w6fw6q 1032 2 to to IN cord-006870-f5w6fw6q 1032 3 dedicated dedicated JJ cord-006870-f5w6fw6q 1032 4 NCC NCC NNP cord-006870-f5w6fw6q 1032 5 models model NNS cord-006870-f5w6fw6q 1032 6 , , , cord-006870-f5w6fw6q 1032 7 standardized standardized JJ cord-006870-f5w6fw6q 1032 8 management management NN cord-006870-f5w6fw6q 1032 9 protocols protocol NNS cord-006870-f5w6fw6q 1032 10 for for IN cord-006870-f5w6fw6q 1032 11 severe severe JJ cord-006870-f5w6fw6q 1032 12 traumatic traumatic JJ cord-006870-f5w6fw6q 1032 13 brain brain NN cord-006870-f5w6fw6q 1033 1 injured injured JJ cord-006870-f5w6fw6q 1033 2 patients patient NNS cord-006870-f5w6fw6q 1033 3 are be VBP cord-006870-f5w6fw6q 1033 4 low low JJ cord-006870-f5w6fw6q 1033 5 - - HYPH cord-006870-f5w6fw6q 1033 6 cost cost NN cord-006870-f5w6fw6q 1033 7 process process NN cord-006870-f5w6fw6q 1033 8 - - HYPH cord-006870-f5w6fw6q 1033 9 targeted target VBN cord-006870-f5w6fw6q 1033 10 intervention intervention NN cord-006870-f5w6fw6q 1033 11 strategies strategy NNS cord-006870-f5w6fw6q 1033 12 that that WDT cord-006870-f5w6fw6q 1033 13 may may MD cord-006870-f5w6fw6q 1033 14 improve improve VB cord-006870-f5w6fw6q 1033 15 clinical clinical JJ cord-006870-f5w6fw6q 1033 16 outcomes outcome NNS cord-006870-f5w6fw6q 1033 17 . . . cord-006870-f5w6fw6q 1034 1 Understanding understand VBG cord-006870-f5w6fw6q 1034 2 the the DT cord-006870-f5w6fw6q 1034 3 differences difference NNS cord-006870-f5w6fw6q 1034 4 in in IN cord-006870-f5w6fw6q 1034 5 processes process NNS cord-006870-f5w6fw6q 1034 6 of of IN cord-006870-f5w6fw6q 1034 7 care care NN cord-006870-f5w6fw6q 1034 8 within within IN cord-006870-f5w6fw6q 1034 9 the the DT cord-006870-f5w6fw6q 1034 10 context context NN cord-006870-f5w6fw6q 1034 11 of of IN cord-006870-f5w6fw6q 1034 12 ICU ICU NNP cord-006870-f5w6fw6q 1034 13 structure structure NN cord-006870-f5w6fw6q 1034 14 is be VBZ cord-006870-f5w6fw6q 1034 15 necessary necessary JJ cord-006870-f5w6fw6q 1034 16 to to TO cord-006870-f5w6fw6q 1034 17 better better RB cord-006870-f5w6fw6q 1034 18 understand understand VB cord-006870-f5w6fw6q 1034 19 mortality mortality NN cord-006870-f5w6fw6q 1034 20 differences difference NNS cord-006870-f5w6fw6q 1034 21 observed observe VBN cord-006870-f5w6fw6q 1034 22 between between IN cord-006870-f5w6fw6q 1034 23 centers center NNS cord-006870-f5w6fw6q 1034 24 , , , cord-006870-f5w6fw6q 1034 25 and and CC cord-006870-f5w6fw6q 1034 26 may may MD cord-006870-f5w6fw6q 1034 27 help help VB cord-006870-f5w6fw6q 1034 28 in in IN cord-006870-f5w6fw6q 1034 29 the the DT cord-006870-f5w6fw6q 1034 30 design design NN cord-006870-f5w6fw6q 1034 31 of of IN cord-006870-f5w6fw6q 1034 32 future future JJ cord-006870-f5w6fw6q 1034 33 trials trial NNS cord-006870-f5w6fw6q 1034 34 for for IN cord-006870-f5w6fw6q 1034 35 severe severe JJ cord-006870-f5w6fw6q 1034 36 TBI TBI NNP cord-006870-f5w6fw6q 1034 37 patients patient NNS cord-006870-f5w6fw6q 1034 38 . . . cord-006870-f5w6fw6q 1035 1 Complex complex JJ cord-006870-f5w6fw6q 1035 2 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 1035 3 care care NN cord-006870-f5w6fw6q 1035 4 of of IN cord-006870-f5w6fw6q 1035 5 patients patient NNS cord-006870-f5w6fw6q 1035 6 in in IN cord-006870-f5w6fw6q 1035 7 the the DT cord-006870-f5w6fw6q 1035 8 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1035 9 care care NN cord-006870-f5w6fw6q 1035 10 unit unit NN cord-006870-f5w6fw6q 1035 11 requires require VBZ cord-006870-f5w6fw6q 1035 12 reliable reliable JJ cord-006870-f5w6fw6q 1035 13 and and CC cord-006870-f5w6fw6q 1035 14 effective effective JJ cord-006870-f5w6fw6q 1035 15 communication communication NN cord-006870-f5w6fw6q 1035 16 to to TO cord-006870-f5w6fw6q 1035 17 minimize minimize VB cord-006870-f5w6fw6q 1035 18 medical medical JJ cord-006870-f5w6fw6q 1035 19 errors error NNS cord-006870-f5w6fw6q 1035 20 . . . cord-006870-f5w6fw6q 1036 1 We -PRON- PRP cord-006870-f5w6fw6q 1036 2 implemented implement VBD cord-006870-f5w6fw6q 1036 3 a a DT cord-006870-f5w6fw6q 1036 4 structured structured JJ cord-006870-f5w6fw6q 1036 5 rounding rounding NN cord-006870-f5w6fw6q 1036 6 process process NN cord-006870-f5w6fw6q 1036 7 that that WDT cord-006870-f5w6fw6q 1036 8 incorporates incorporate VBZ cord-006870-f5w6fw6q 1036 9 AHRQ AHRQ NNP cord-006870-f5w6fw6q 1036 10 - - HYPH cord-006870-f5w6fw6q 1036 11 endorsed endorse VBN cord-006870-f5w6fw6q 1036 12 Team Team NNP cord-006870-f5w6fw6q 1036 13 Strategies Strategies NNPS cord-006870-f5w6fw6q 1036 14 and and CC cord-006870-f5w6fw6q 1036 15 Tools Tools NNPS cord-006870-f5w6fw6q 1036 16 to to TO cord-006870-f5w6fw6q 1036 17 Enhance enhance VB cord-006870-f5w6fw6q 1036 18 Performance Performance NNP cord-006870-f5w6fw6q 1036 19 and and CC cord-006870-f5w6fw6q 1036 20 Patient Patient NNP cord-006870-f5w6fw6q 1036 21 Safety Safety NNP cord-006870-f5w6fw6q 1036 22 ( ( -LRB- cord-006870-f5w6fw6q 1036 23 Team Team NNP cord-006870-f5w6fw6q 1036 24 STEPPS STEPPS NNP cord-006870-f5w6fw6q 1036 25 ) ) -RRB- cord-006870-f5w6fw6q 1036 26 to to TO cord-006870-f5w6fw6q 1036 27 improve improve VB cord-006870-f5w6fw6q 1036 28 interprofessional interprofessional JJ cord-006870-f5w6fw6q 1036 29 collaboration collaboration NN cord-006870-f5w6fw6q 1036 30 between between IN cord-006870-f5w6fw6q 1036 31 team team NN cord-006870-f5w6fw6q 1036 32 members member NNS cord-006870-f5w6fw6q 1036 33 . . . cord-006870-f5w6fw6q 1037 1 We -PRON- PRP cord-006870-f5w6fw6q 1037 2 convened convene VBD cord-006870-f5w6fw6q 1037 3 a a DT cord-006870-f5w6fw6q 1037 4 project project NN cord-006870-f5w6fw6q 1037 5 team team NN cord-006870-f5w6fw6q 1037 6 of of IN cord-006870-f5w6fw6q 1037 7 physicians physician NNS cord-006870-f5w6fw6q 1037 8 , , , cord-006870-f5w6fw6q 1037 9 advanced advanced JJ cord-006870-f5w6fw6q 1037 10 practice practice NN cord-006870-f5w6fw6q 1037 11 providers provider NNS cord-006870-f5w6fw6q 1037 12 ( ( -LRB- cord-006870-f5w6fw6q 1037 13 APPs app NNS cord-006870-f5w6fw6q 1037 14 ) ) -RRB- cord-006870-f5w6fw6q 1037 15 , , , cord-006870-f5w6fw6q 1037 16 nurses nurse NNS cord-006870-f5w6fw6q 1037 17 , , , cord-006870-f5w6fw6q 1037 18 respiratory respiratory JJ cord-006870-f5w6fw6q 1037 19 therapists therapist NNS cord-006870-f5w6fw6q 1037 20 , , , cord-006870-f5w6fw6q 1037 21 and and CC cord-006870-f5w6fw6q 1037 22 pharmacists pharmacist NNS cord-006870-f5w6fw6q 1037 23 in in IN cord-006870-f5w6fw6q 1037 24 a a DT cord-006870-f5w6fw6q 1037 25 16-bed 16-bed CD cord-006870-f5w6fw6q 1037 26 NICU NICU NNP cord-006870-f5w6fw6q 1037 27 . . . cord-006870-f5w6fw6q 1038 1 We -PRON- PRP cord-006870-f5w6fw6q 1038 2 defined define VBD cord-006870-f5w6fw6q 1038 3 structured structured JJ cord-006870-f5w6fw6q 1038 4 rounding rounding NN cord-006870-f5w6fw6q 1038 5 processes process NNS cord-006870-f5w6fw6q 1038 6 and and CC cord-006870-f5w6fw6q 1038 7 implemented implement VBN cord-006870-f5w6fw6q 1038 8 Team Team NNP cord-006870-f5w6fw6q 1038 9 STEPPS STEPPS NNP cord-006870-f5w6fw6q 1038 10 strategies strategy NNS cord-006870-f5w6fw6q 1038 11 to to TO cord-006870-f5w6fw6q 1038 12 promote promote VB cord-006870-f5w6fw6q 1038 13 closed close VBN cord-006870-f5w6fw6q 1038 14 - - HYPH cord-006870-f5w6fw6q 1038 15 loop loop NN cord-006870-f5w6fw6q 1038 16 communication communication NN cord-006870-f5w6fw6q 1038 17 between between IN cord-006870-f5w6fw6q 1038 18 team team NN cord-006870-f5w6fw6q 1038 19 members member NNS cord-006870-f5w6fw6q 1038 20 during during IN cord-006870-f5w6fw6q 1038 21 daily daily JJ cord-006870-f5w6fw6q 1038 22 rounds round NNS cord-006870-f5w6fw6q 1038 23 . . . cord-006870-f5w6fw6q 1039 1 The the DT cord-006870-f5w6fw6q 1039 2 Assessment Assessment NNP cord-006870-f5w6fw6q 1039 3 of of IN cord-006870-f5w6fw6q 1039 4 Interprofessional Interprofessional NNP cord-006870-f5w6fw6q 1039 5 Team Team NNP cord-006870-f5w6fw6q 1039 6 Collaboration Collaboration NNP cord-006870-f5w6fw6q 1039 7 Scale Scale NNP cord-006870-f5w6fw6q 1039 8 ( ( -LRB- cord-006870-f5w6fw6q 1039 9 AITCS AITCS NNP cord-006870-f5w6fw6q 1039 10 - - HYPH cord-006870-f5w6fw6q 1039 11 II II NNP cord-006870-f5w6fw6q 1039 12 ) ) -RRB- cord-006870-f5w6fw6q 1039 13 was be VBD cord-006870-f5w6fw6q 1039 14 administered administer VBN cord-006870-f5w6fw6q 1039 15 to to TO cord-006870-f5w6fw6q 1039 16 team team VB cord-006870-f5w6fw6q 1039 17 members member NNS cord-006870-f5w6fw6q 1039 18 at at IN cord-006870-f5w6fw6q 1039 19 baseline baseline NN cord-006870-f5w6fw6q 1039 20 and and CC cord-006870-f5w6fw6q 1039 21 16 16 CD cord-006870-f5w6fw6q 1039 22 months month NNS cord-006870-f5w6fw6q 1039 23 post post NN cord-006870-f5w6fw6q 1039 24 - - NN cord-006870-f5w6fw6q 1039 25 intervention intervention NN cord-006870-f5w6fw6q 1039 26 . . . cord-006870-f5w6fw6q 1040 1 Impact impact NN cord-006870-f5w6fw6q 1040 2 on on IN cord-006870-f5w6fw6q 1040 3 overall overall JJ cord-006870-f5w6fw6q 1040 4 team team NN cord-006870-f5w6fw6q 1040 5 collaboration collaboration NN cord-006870-f5w6fw6q 1040 6 and and CC cord-006870-f5w6fw6q 1040 7 subscale subscale NN cord-006870-f5w6fw6q 1040 8 domains domain NNS cord-006870-f5w6fw6q 1040 9 of of IN cord-006870-f5w6fw6q 1040 10 team team NN cord-006870-f5w6fw6q 1040 11 partnership partnership NN cord-006870-f5w6fw6q 1040 12 , , , cord-006870-f5w6fw6q 1040 13 cooperation cooperation NN cord-006870-f5w6fw6q 1040 14 and and CC cord-006870-f5w6fw6q 1040 15 coordination coordination NN cord-006870-f5w6fw6q 1040 16 was be VBD cord-006870-f5w6fw6q 1040 17 assessed assess VBN cord-006870-f5w6fw6q 1040 18 . . . cord-006870-f5w6fw6q 1041 1 The the DT cord-006870-f5w6fw6q 1041 2 possible possible JJ cord-006870-f5w6fw6q 1041 3 range range NN cord-006870-f5w6fw6q 1041 4 of of IN cord-006870-f5w6fw6q 1041 5 the the DT cord-006870-f5w6fw6q 1041 6 overall overall JJ cord-006870-f5w6fw6q 1041 7 collaboration collaboration NN cord-006870-f5w6fw6q 1041 8 score score NN cord-006870-f5w6fw6q 1041 9 is be VBZ cord-006870-f5w6fw6q 1041 10 23 23 CD cord-006870-f5w6fw6q 1041 11 to to IN cord-006870-f5w6fw6q 1041 12 115 115 CD cord-006870-f5w6fw6q 1041 13 ; ; : cord-006870-f5w6fw6q 1041 14 higher high JJR cord-006870-f5w6fw6q 1041 15 scores score NNS cord-006870-f5w6fw6q 1041 16 indicate indicate VBP cord-006870-f5w6fw6q 1041 17 better well JJR cord-006870-f5w6fw6q 1041 18 collaboration collaboration NN cord-006870-f5w6fw6q 1041 19 . . . cord-006870-f5w6fw6q 1042 1 The the DT cord-006870-f5w6fw6q 1042 2 survey survey NN cord-006870-f5w6fw6q 1042 3 was be VBD cord-006870-f5w6fw6q 1042 4 completed complete VBN cord-006870-f5w6fw6q 1042 5 by by IN cord-006870-f5w6fw6q 1042 6 61 61 CD cord-006870-f5w6fw6q 1042 7 ( ( -LRB- cord-006870-f5w6fw6q 1042 8 85 85 CD cord-006870-f5w6fw6q 1042 9 % % NN cord-006870-f5w6fw6q 1042 10 ) ) -RRB- cord-006870-f5w6fw6q 1042 11 staff staff NN cord-006870-f5w6fw6q 1042 12 at at IN cord-006870-f5w6fw6q 1042 13 baseline baseline NN cord-006870-f5w6fw6q 1042 14 , , , cord-006870-f5w6fw6q 1042 15 and and CC cord-006870-f5w6fw6q 1042 16 54 54 CD cord-006870-f5w6fw6q 1043 1 ( ( -LRB- cord-006870-f5w6fw6q 1043 2 77 77 CD cord-006870-f5w6fw6q 1043 3 % % NN cord-006870-f5w6fw6q 1043 4 ) ) -RRB- cord-006870-f5w6fw6q 1043 5 staff staff NN cord-006870-f5w6fw6q 1043 6 post post NN cord-006870-f5w6fw6q 1043 7 - - NN cord-006870-f5w6fw6q 1043 8 intervention intervention NN cord-006870-f5w6fw6q 1043 9 . . . cord-006870-f5w6fw6q 1044 1 Overall overall JJ cord-006870-f5w6fw6q 1044 2 team team NN cord-006870-f5w6fw6q 1044 3 collaboration collaboration NN cord-006870-f5w6fw6q 1044 4 scores score NNS cord-006870-f5w6fw6q 1044 5 improved improve VBD cord-006870-f5w6fw6q 1044 6 significantly significantly RB cord-006870-f5w6fw6q 1044 7 pre pre VBD cord-006870-f5w6fw6q 1044 8 and and CC cord-006870-f5w6fw6q 1044 9 post post JJ cord-006870-f5w6fw6q 1044 10 - - NN cord-006870-f5w6fw6q 1044 11 intervention intervention JJ cord-006870-f5w6fw6q 1044 12 ( ( -LRB- cord-006870-f5w6fw6q 1044 13 78.0 78.0 CD cord-006870-f5w6fw6q 1044 14 ± ± NNP cord-006870-f5w6fw6q 1044 15 18 18 CD cord-006870-f5w6fw6q 1044 16 vs vs IN cord-006870-f5w6fw6q 1044 17 89.7 89.7 CD cord-006870-f5w6fw6q 1044 18 ± ± NNP cord-006870-f5w6fw6q 1044 19 15 15 CD cord-006870-f5w6fw6q 1044 20 , , , cord-006870-f5w6fw6q 1044 21 p p NN cord-006870-f5w6fw6q 1044 22 < < XX cord-006870-f5w6fw6q 1044 23 .001 .001 CD cord-006870-f5w6fw6q 1044 24 ) ) -RRB- cord-006870-f5w6fw6q 1044 25 , , , cord-006870-f5w6fw6q 1044 26 as as IN cord-006870-f5w6fw6q 1044 27 did do VBD cord-006870-f5w6fw6q 1044 28 subdomain subdomain NN cord-006870-f5w6fw6q 1044 29 scores score NNS cord-006870-f5w6fw6q 1044 30 of of IN cord-006870-f5w6fw6q 1044 31 team team NN cord-006870-f5w6fw6q 1044 32 partnership partnership NN cord-006870-f5w6fw6q 1044 33 ( ( -LRB- cord-006870-f5w6fw6q 1044 34 27.9 27.9 CD cord-006870-f5w6fw6q 1044 35 ±6.9 ±6.9 NNS cord-006870-f5w6fw6q 1044 36 vs vs IN cord-006870-f5w6fw6q 1044 37 31.9 31.9 CD cord-006870-f5w6fw6q 1044 38 ± ± CD cord-006870-f5w6fw6q 1044 39 5.2 5.2 CD cord-006870-f5w6fw6q 1044 40 , , , cord-006870-f5w6fw6q 1044 41 p p NN cord-006870-f5w6fw6q 1044 42 < < XX cord-006870-f5w6fw6q 1044 43 .001 .001 CD cord-006870-f5w6fw6q 1044 44 ) ) -RRB- cord-006870-f5w6fw6q 1044 45 , , , cord-006870-f5w6fw6q 1044 46 collaboration collaboration NN cord-006870-f5w6fw6q 1044 47 ( ( -LRB- cord-006870-f5w6fw6q 1044 48 28.1 28.1 CD cord-006870-f5w6fw6q 1044 49 ± ± CD cord-006870-f5w6fw6q 1044 50 6.3 6.3 CD cord-006870-f5w6fw6q 1044 51 vs vs IN cord-006870-f5w6fw6q 1044 52 32.1 32.1 CD cord-006870-f5w6fw6q 1044 53 ± ± CD cord-006870-f5w6fw6q 1044 54 5.7 5.7 CD cord-006870-f5w6fw6q 1044 55 ) ) -RRB- cord-006870-f5w6fw6q 1044 56 , , , cord-006870-f5w6fw6q 1044 57 and and CC cord-006870-f5w6fw6q 1044 58 coordination coordination NN cord-006870-f5w6fw6q 1044 59 ( ( -LRB- cord-006870-f5w6fw6q 1044 60 22.1 22.1 CD cord-006870-f5w6fw6q 1044 61 ±6.6 ±6.6 JJ cord-006870-f5w6fw6q 1044 62 vs vs IN cord-006870-f5w6fw6q 1044 63 25.7 25.7 CD cord-006870-f5w6fw6q 1044 64 ± ± CD cord-006870-f5w6fw6q 1044 65 5.7 5.7 CD cord-006870-f5w6fw6q 1044 66 . . . cord-006870-f5w6fw6q 1045 1 , , , cord-006870-f5w6fw6q 1045 2 p p NN cord-006870-f5w6fw6q 1045 3 < < XX cord-006870-f5w6fw6q 1045 4 .001 .001 CD cord-006870-f5w6fw6q 1045 5 ) ) -RRB- cord-006870-f5w6fw6q 1045 6 . . . cord-006870-f5w6fw6q 1046 1 Perceived perceive VBN cord-006870-f5w6fw6q 1046 2 shared share VBN cord-006870-f5w6fw6q 1046 3 understanding understanding NN cord-006870-f5w6fw6q 1046 4 of of IN cord-006870-f5w6fw6q 1046 5 patient patient JJ cord-006870-f5w6fw6q 1046 6 daily daily JJ cord-006870-f5w6fw6q 1046 7 goals goal NNS cord-006870-f5w6fw6q 1046 8 between between IN cord-006870-f5w6fw6q 1046 9 nurses nurse NNS cord-006870-f5w6fw6q 1046 10 and and CC cord-006870-f5w6fw6q 1046 11 providers provider NNS cord-006870-f5w6fw6q 1046 12 ( ( -LRB- cord-006870-f5w6fw6q 1046 13 physicians physician NNS cord-006870-f5w6fw6q 1046 14 / / SYM cord-006870-f5w6fw6q 1046 15 APPs app NNS cord-006870-f5w6fw6q 1046 16 ) ) -RRB- cord-006870-f5w6fw6q 1046 17 increased increase VBD cord-006870-f5w6fw6q 1046 18 from from IN cord-006870-f5w6fw6q 1046 19 58 58 CD cord-006870-f5w6fw6q 1046 20 % % NN cord-006870-f5w6fw6q 1046 21 to to IN cord-006870-f5w6fw6q 1046 22 91 91 CD cord-006870-f5w6fw6q 1046 23 % % NN cord-006870-f5w6fw6q 1047 1 ( ( -LRB- cord-006870-f5w6fw6q 1047 2 Chi Chi NNP cord-006870-f5w6fw6q 1047 3 - - HYPH cord-006870-f5w6fw6q 1047 4 square square NNP cord-006870-f5w6fw6q 1047 5 15.7 15.7 CD cord-006870-f5w6fw6q 1047 6 ; ; : cord-006870-f5w6fw6q 1047 7 p p NN cord-006870-f5w6fw6q 1047 8 < < XX cord-006870-f5w6fw6q 1047 9 .001 .001 CD cord-006870-f5w6fw6q 1047 10 ) ) -RRB- cord-006870-f5w6fw6q 1047 11 . . . cord-006870-f5w6fw6q 1048 1 68 68 CD cord-006870-f5w6fw6q 1048 2 % % NN cord-006870-f5w6fw6q 1048 3 of of IN cord-006870-f5w6fw6q 1048 4 staff staff NN cord-006870-f5w6fw6q 1048 5 reported report VBD cord-006870-f5w6fw6q 1048 6 that that IN cord-006870-f5w6fw6q 1048 7 the the DT cord-006870-f5w6fw6q 1048 8 intervention intervention NN cord-006870-f5w6fw6q 1048 9 shortened shorten VBD cord-006870-f5w6fw6q 1048 10 or or CC cord-006870-f5w6fw6q 1048 11 did do VBD cord-006870-f5w6fw6q 1048 12 not not RB cord-006870-f5w6fw6q 1048 13 affect affect VB cord-006870-f5w6fw6q 1048 14 the the DT cord-006870-f5w6fw6q 1048 15 duration duration NN cord-006870-f5w6fw6q 1048 16 of of IN cord-006870-f5w6fw6q 1048 17 rounds round NNS cord-006870-f5w6fw6q 1048 18 . . . cord-006870-f5w6fw6q 1049 1 Of of IN cord-006870-f5w6fw6q 1049 2 those those DT cord-006870-f5w6fw6q 1049 3 who who WP cord-006870-f5w6fw6q 1049 4 reported report VBD cord-006870-f5w6fw6q 1049 5 longer long JJR cord-006870-f5w6fw6q 1049 6 duration duration NN cord-006870-f5w6fw6q 1049 7 of of IN cord-006870-f5w6fw6q 1049 8 rounds round NNS cord-006870-f5w6fw6q 1049 9 , , , cord-006870-f5w6fw6q 1049 10 100 100 CD cord-006870-f5w6fw6q 1049 11 % % NN cord-006870-f5w6fw6q 1049 12 responded respond VBD cord-006870-f5w6fw6q 1049 13 that that IN cord-006870-f5w6fw6q 1049 14 the the DT cord-006870-f5w6fw6q 1049 15 intervention intervention NN cord-006870-f5w6fw6q 1049 16 was be VBD cord-006870-f5w6fw6q 1049 17 worthwhile worthwhile JJ cord-006870-f5w6fw6q 1049 18 . . . cord-006870-f5w6fw6q 1050 1 Interprofessional Interprofessional NNP cord-006870-f5w6fw6q 1050 2 team team NN cord-006870-f5w6fw6q 1050 3 collaboration collaboration NN cord-006870-f5w6fw6q 1050 4 can can MD cord-006870-f5w6fw6q 1050 5 be be VB cord-006870-f5w6fw6q 1050 6 enhanced enhance VBN cord-006870-f5w6fw6q 1050 7 by by IN cord-006870-f5w6fw6q 1050 8 structured structured JJ cord-006870-f5w6fw6q 1050 9 rounding rounding NN cord-006870-f5w6fw6q 1050 10 and and CC cord-006870-f5w6fw6q 1050 11 communication communication NN cord-006870-f5w6fw6q 1050 12 workflows workflow NNS cord-006870-f5w6fw6q 1050 13 . . . cord-006870-f5w6fw6q 1051 1 By by IN cord-006870-f5w6fw6q 1051 2 promoting promote VBG cord-006870-f5w6fw6q 1051 3 closed close VBN cord-006870-f5w6fw6q 1051 4 - - HYPH cord-006870-f5w6fw6q 1051 5 loop loop NN cord-006870-f5w6fw6q 1051 6 communication communication NN cord-006870-f5w6fw6q 1051 7 during during IN cord-006870-f5w6fw6q 1051 8 daily daily JJ cord-006870-f5w6fw6q 1051 9 rounds round NNS cord-006870-f5w6fw6q 1051 10 , , , cord-006870-f5w6fw6q 1051 11 shared share VBD cord-006870-f5w6fw6q 1051 12 understanding understanding NN cord-006870-f5w6fw6q 1051 13 of of IN cord-006870-f5w6fw6q 1051 14 patient patient JJ cord-006870-f5w6fw6q 1051 15 daily daily JJ cord-006870-f5w6fw6q 1051 16 goals goal NNS cord-006870-f5w6fw6q 1051 17 between between IN cord-006870-f5w6fw6q 1051 18 team team NN cord-006870-f5w6fw6q 1051 19 members member NNS cord-006870-f5w6fw6q 1051 20 is be VBZ cord-006870-f5w6fw6q 1051 21 increased increase VBN cord-006870-f5w6fw6q 1051 22 , , , cord-006870-f5w6fw6q 1051 23 and and CC cord-006870-f5w6fw6q 1051 24 may may MD cord-006870-f5w6fw6q 1051 25 optimize optimize VB cord-006870-f5w6fw6q 1051 26 quality quality NN cord-006870-f5w6fw6q 1051 27 and and CC cord-006870-f5w6fw6q 1051 28 safety safety NN cord-006870-f5w6fw6q 1051 29 of of IN cord-006870-f5w6fw6q 1051 30 patient patient JJ cord-006870-f5w6fw6q 1051 31 care care NN cord-006870-f5w6fw6q 1051 32 . . . cord-006870-f5w6fw6q 1052 1 Advanced advanced JJ cord-006870-f5w6fw6q 1052 2 practice practice NN cord-006870-f5w6fw6q 1052 3 providers provider NNS cord-006870-f5w6fw6q 1052 4 ( ( -LRB- cord-006870-f5w6fw6q 1052 5 APPs app NNS cord-006870-f5w6fw6q 1052 6 ) ) -RRB- cord-006870-f5w6fw6q 1052 7 are be VBP cord-006870-f5w6fw6q 1052 8 increasingly increasingly RB cord-006870-f5w6fw6q 1052 9 utilized utilize VBN cord-006870-f5w6fw6q 1052 10 to to TO cord-006870-f5w6fw6q 1052 11 provide provide VB cord-006870-f5w6fw6q 1052 12 clinical clinical JJ cord-006870-f5w6fw6q 1052 13 care care NN cord-006870-f5w6fw6q 1052 14 within within IN cord-006870-f5w6fw6q 1052 15 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1052 16 care care NN cord-006870-f5w6fw6q 1052 17 units unit NNS cord-006870-f5w6fw6q 1052 18 ( ( -LRB- cord-006870-f5w6fw6q 1052 19 NSICU NSICU NNP cord-006870-f5w6fw6q 1052 20 ) ) -RRB- cord-006870-f5w6fw6q 1052 21 . . . cord-006870-f5w6fw6q 1053 1 Despite despite IN cord-006870-f5w6fw6q 1053 2 the the DT cord-006870-f5w6fw6q 1053 3 complex complex JJ cord-006870-f5w6fw6q 1053 4 issues issue NNS cord-006870-f5w6fw6q 1053 5 in in IN cord-006870-f5w6fw6q 1053 6 this this DT cord-006870-f5w6fw6q 1053 7 patient patient JJ cord-006870-f5w6fw6q 1053 8 population population NN cord-006870-f5w6fw6q 1053 9 , , , cord-006870-f5w6fw6q 1053 10 the the DT cord-006870-f5w6fw6q 1053 11 specific specific JJ cord-006870-f5w6fw6q 1053 12 educational educational JJ cord-006870-f5w6fw6q 1053 13 and and CC cord-006870-f5w6fw6q 1053 14 orientation orientation NN cord-006870-f5w6fw6q 1053 15 needs need NNS cord-006870-f5w6fw6q 1053 16 of of IN cord-006870-f5w6fw6q 1053 17 these these DT cord-006870-f5w6fw6q 1053 18 providers provider NNS cord-006870-f5w6fw6q 1053 19 have have VBP cord-006870-f5w6fw6q 1053 20 not not RB cord-006870-f5w6fw6q 1053 21 been be VBN cord-006870-f5w6fw6q 1053 22 established establish VBN cord-006870-f5w6fw6q 1053 23 . . . cord-006870-f5w6fw6q 1054 1 To to TO cord-006870-f5w6fw6q 1054 2 meet meet VB cord-006870-f5w6fw6q 1054 3 the the DT cord-006870-f5w6fw6q 1054 4 demands demand NNS cord-006870-f5w6fw6q 1054 5 for for IN cord-006870-f5w6fw6q 1054 6 rapidly rapidly RB cord-006870-f5w6fw6q 1054 7 and and CC cord-006870-f5w6fw6q 1054 8 effectively effectively RB cord-006870-f5w6fw6q 1054 9 training train VBG cord-006870-f5w6fw6q 1054 10 APPs app NNS cord-006870-f5w6fw6q 1054 11 to to TO cord-006870-f5w6fw6q 1054 12 provide provide VB cord-006870-f5w6fw6q 1054 13 advanced advanced JJ cord-006870-f5w6fw6q 1054 14 neurocritical neurocritical JJ cord-006870-f5w6fw6q 1054 15 care care NN cord-006870-f5w6fw6q 1054 16 ( ( -LRB- cord-006870-f5w6fw6q 1054 17 NCC NCC NNP cord-006870-f5w6fw6q 1054 18 ) ) -RRB- cord-006870-f5w6fw6q 1054 19 , , , cord-006870-f5w6fw6q 1054 20 a a DT cord-006870-f5w6fw6q 1054 21 structured structured JJ cord-006870-f5w6fw6q 1054 22 educational educational JJ cord-006870-f5w6fw6q 1054 23 curriculum curriculum NN cord-006870-f5w6fw6q 1054 24 was be VBD cord-006870-f5w6fw6q 1054 25 developed develop VBN cord-006870-f5w6fw6q 1054 26 and and CC cord-006870-f5w6fw6q 1054 27 integrated integrate VBN cord-006870-f5w6fw6q 1054 28 within within IN cord-006870-f5w6fw6q 1054 29 the the DT cord-006870-f5w6fw6q 1054 30 standard standard JJ cord-006870-f5w6fw6q 1054 31 orientation orientation NN cord-006870-f5w6fw6q 1054 32 and and CC cord-006870-f5w6fw6q 1054 33 on on IN cord-006870-f5w6fw6q 1054 34 - - HYPH cord-006870-f5w6fw6q 1054 35 boarding boarding NN cord-006870-f5w6fw6q 1054 36 process process NN cord-006870-f5w6fw6q 1054 37 for for IN cord-006870-f5w6fw6q 1054 38 newly newly RB cord-006870-f5w6fw6q 1054 39 - - HYPH cord-006870-f5w6fw6q 1054 40 hired hire VBN cord-006870-f5w6fw6q 1054 41 APP app NN cord-006870-f5w6fw6q 1054 42 within within IN cord-006870-f5w6fw6q 1054 43 our -PRON- PRP$ cord-006870-f5w6fw6q 1054 44 NSICU NSICU NNP cord-006870-f5w6fw6q 1054 45 . . . cord-006870-f5w6fw6q 1055 1 This this DT cord-006870-f5w6fw6q 1055 2 curriculum curriculum NN cord-006870-f5w6fw6q 1055 3 was be VBD cord-006870-f5w6fw6q 1055 4 designed design VBN cord-006870-f5w6fw6q 1055 5 with with IN cord-006870-f5w6fw6q 1055 6 measurable measurable JJ cord-006870-f5w6fw6q 1055 7 learning learning NN cord-006870-f5w6fw6q 1055 8 goals goal NNS cord-006870-f5w6fw6q 1055 9 , , , cord-006870-f5w6fw6q 1055 10 objective objective JJ cord-006870-f5w6fw6q 1055 11 assessments assessment NNS cord-006870-f5w6fw6q 1055 12 of of IN cord-006870-f5w6fw6q 1055 13 goal goal NN cord-006870-f5w6fw6q 1055 14 achievement achievement NN cord-006870-f5w6fw6q 1055 15 , , , cord-006870-f5w6fw6q 1055 16 and and CC cord-006870-f5w6fw6q 1055 17 opportunities opportunity NNS cord-006870-f5w6fw6q 1055 18 for for IN cord-006870-f5w6fw6q 1055 19 additional additional JJ cord-006870-f5w6fw6q 1055 20 education education NN cord-006870-f5w6fw6q 1055 21 and and CC cord-006870-f5w6fw6q 1055 22 remediation remediation NN cord-006870-f5w6fw6q 1055 23 at at IN cord-006870-f5w6fw6q 1055 24 multiple multiple JJ cord-006870-f5w6fw6q 1055 25 steps step NNS cord-006870-f5w6fw6q 1055 26 within within IN cord-006870-f5w6fw6q 1055 27 the the DT cord-006870-f5w6fw6q 1055 28 program program NN cord-006870-f5w6fw6q 1055 29 . . . cord-006870-f5w6fw6q 1056 1 The the DT cord-006870-f5w6fw6q 1056 2 curriculum curriculum NN cord-006870-f5w6fw6q 1056 3 has have VBZ cord-006870-f5w6fw6q 1056 4 three three CD cord-006870-f5w6fw6q 1056 5 phases phase NNS cord-006870-f5w6fw6q 1056 6 with with IN cord-006870-f5w6fw6q 1056 7 distinct distinct JJ cord-006870-f5w6fw6q 1056 8 goals goal NNS cord-006870-f5w6fw6q 1056 9 and and CC cord-006870-f5w6fw6q 1056 10 assessments assessment NNS cord-006870-f5w6fw6q 1056 11 . . . cord-006870-f5w6fw6q 1057 1 Phase phase NN cord-006870-f5w6fw6q 1058 1 I -PRON- PRP cord-006870-f5w6fw6q 1058 2 covers cover VBZ cord-006870-f5w6fw6q 1058 3 basic basic JJ cord-006870-f5w6fw6q 1058 4 triage triage NN cord-006870-f5w6fw6q 1058 5 and and CC cord-006870-f5w6fw6q 1058 6 resuscitation resuscitation NN cord-006870-f5w6fw6q 1058 7 issues issue NNS cord-006870-f5w6fw6q 1058 8 for for IN cord-006870-f5w6fw6q 1058 9 the the DT cord-006870-f5w6fw6q 1058 10 acutely acutely RB cord-006870-f5w6fw6q 1058 11 - - HYPH cord-006870-f5w6fw6q 1058 12 decompensating decompensate VBG cord-006870-f5w6fw6q 1058 13 patient patient NN cord-006870-f5w6fw6q 1058 14 . . . cord-006870-f5w6fw6q 1059 1 Phase phase NN cord-006870-f5w6fw6q 1059 2 II II NNP cord-006870-f5w6fw6q 1059 3 covers cover VBZ cord-006870-f5w6fw6q 1059 4 general general JJ cord-006870-f5w6fw6q 1059 5 critical critical JJ cord-006870-f5w6fw6q 1059 6 care care NN cord-006870-f5w6fw6q 1059 7 principles principle NNS cord-006870-f5w6fw6q 1059 8 in in IN cord-006870-f5w6fw6q 1059 9 significantly significantly RB cord-006870-f5w6fw6q 1059 10 greater great JJR cord-006870-f5w6fw6q 1059 11 depth depth NN cord-006870-f5w6fw6q 1059 12 . . . cord-006870-f5w6fw6q 1060 1 Phase phase NN cord-006870-f5w6fw6q 1060 2 III III NNP cord-006870-f5w6fw6q 1060 3 provides provide VBZ cord-006870-f5w6fw6q 1060 4 detailed detailed JJ cord-006870-f5w6fw6q 1060 5 experience experience NN cord-006870-f5w6fw6q 1060 6 and and CC cord-006870-f5w6fw6q 1060 7 exposure exposure NN cord-006870-f5w6fw6q 1060 8 to to IN cord-006870-f5w6fw6q 1060 9 specific specific JJ cord-006870-f5w6fw6q 1060 10 NCC NCC NNP cord-006870-f5w6fw6q 1060 11 issues issue NNS cord-006870-f5w6fw6q 1060 12 . . . cord-006870-f5w6fw6q 1061 1 Each each DT cord-006870-f5w6fw6q 1061 2 phase phase NN cord-006870-f5w6fw6q 1061 3 incorporates incorporate VBZ cord-006870-f5w6fw6q 1061 4 relevant relevant JJ cord-006870-f5w6fw6q 1061 5 reading reading NN cord-006870-f5w6fw6q 1061 6 assignments assignment NNS cord-006870-f5w6fw6q 1061 7 with with IN cord-006870-f5w6fw6q 1061 8 a a DT cord-006870-f5w6fw6q 1061 9 tailored tailored JJ cord-006870-f5w6fw6q 1061 10 study study NN cord-006870-f5w6fw6q 1061 11 guide guide NN cord-006870-f5w6fw6q 1061 12 , , , cord-006870-f5w6fw6q 1061 13 as as RB cord-006870-f5w6fw6q 1061 14 well well RB cord-006870-f5w6fw6q 1061 15 as as IN cord-006870-f5w6fw6q 1061 16 a a DT cord-006870-f5w6fw6q 1061 17 multiple multiple JJ cord-006870-f5w6fw6q 1061 18 - - HYPH cord-006870-f5w6fw6q 1061 19 choice choice NN cord-006870-f5w6fw6q 1061 20 question question NN cord-006870-f5w6fw6q 1061 21 post post NN cord-006870-f5w6fw6q 1061 22 - - JJ cord-006870-f5w6fw6q 1061 23 test test NN cord-006870-f5w6fw6q 1061 24 to to TO cord-006870-f5w6fw6q 1061 25 demonstrate demonstrate VB cord-006870-f5w6fw6q 1061 26 knowledge knowledge NN cord-006870-f5w6fw6q 1061 27 acquisition acquisition NN cord-006870-f5w6fw6q 1061 28 . . . cord-006870-f5w6fw6q 1062 1 Phases Phases NNP cord-006870-f5w6fw6q 1062 2 II II NNP cord-006870-f5w6fw6q 1062 3 and and CC cord-006870-f5w6fw6q 1062 4 III III NNP cord-006870-f5w6fw6q 1062 5 also also RB cord-006870-f5w6fw6q 1062 6 include include VBP cord-006870-f5w6fw6q 1062 7 an an DT cord-006870-f5w6fw6q 1062 8 oral oral JJ cord-006870-f5w6fw6q 1062 9 exam exam NN cord-006870-f5w6fw6q 1062 10 incorporating incorporate VBG cord-006870-f5w6fw6q 1062 11 hypothetical hypothetical JJ cord-006870-f5w6fw6q 1062 12 patient patient NN cord-006870-f5w6fw6q 1062 13 scenarios scenario NNS cord-006870-f5w6fw6q 1062 14 to to TO cord-006870-f5w6fw6q 1062 15 allow allow VB cord-006870-f5w6fw6q 1062 16 the the DT cord-006870-f5w6fw6q 1062 17 APP app NN cord-006870-f5w6fw6q 1062 18 to to TO cord-006870-f5w6fw6q 1062 19 demonstrate demonstrate VB cord-006870-f5w6fw6q 1062 20 comprehension comprehension NN cord-006870-f5w6fw6q 1062 21 and and CC cord-006870-f5w6fw6q 1062 22 application application NN cord-006870-f5w6fw6q 1062 23 of of IN cord-006870-f5w6fw6q 1062 24 the the DT cord-006870-f5w6fw6q 1062 25 goals goal NNS cord-006870-f5w6fw6q 1062 26 for for IN cord-006870-f5w6fw6q 1062 27 each each DT cord-006870-f5w6fw6q 1062 28 phase phase NN cord-006870-f5w6fw6q 1062 29 . . . cord-006870-f5w6fw6q 1063 1 Each each DT cord-006870-f5w6fw6q 1063 2 phase phase NN cord-006870-f5w6fw6q 1063 3 lasts last VBZ cord-006870-f5w6fw6q 1063 4 approximately approximately RB cord-006870-f5w6fw6q 1063 5 4 4 CD cord-006870-f5w6fw6q 1063 6 to to TO cord-006870-f5w6fw6q 1063 7 8 8 CD cord-006870-f5w6fw6q 1063 8 weeks week NNS cord-006870-f5w6fw6q 1063 9 with with IN cord-006870-f5w6fw6q 1063 10 the the DT cord-006870-f5w6fw6q 1063 11 expectation expectation NN cord-006870-f5w6fw6q 1063 12 that that IN cord-006870-f5w6fw6q 1063 13 the the DT cord-006870-f5w6fw6q 1063 14 entire entire JJ cord-006870-f5w6fw6q 1063 15 orientation orientation NN cord-006870-f5w6fw6q 1063 16 curriculum curriculum NN cord-006870-f5w6fw6q 1063 17 will will MD cord-006870-f5w6fw6q 1063 18 be be VB cord-006870-f5w6fw6q 1063 19 completed complete VBN cord-006870-f5w6fw6q 1063 20 within within IN cord-006870-f5w6fw6q 1063 21 six six CD cord-006870-f5w6fw6q 1063 22 months month NNS cord-006870-f5w6fw6q 1063 23 of of IN cord-006870-f5w6fw6q 1063 24 employment employment NN cord-006870-f5w6fw6q 1063 25 . . . cord-006870-f5w6fw6q 1064 1 In in IN cord-006870-f5w6fw6q 1064 2 addition addition NN cord-006870-f5w6fw6q 1064 3 to to IN cord-006870-f5w6fw6q 1064 4 the the DT cord-006870-f5w6fw6q 1064 5 educational educational JJ cord-006870-f5w6fw6q 1064 6 curriculum curriculum NN cord-006870-f5w6fw6q 1064 7 , , , cord-006870-f5w6fw6q 1064 8 phases phase NNS cord-006870-f5w6fw6q 1064 9 I -PRON- PRP cord-006870-f5w6fw6q 1064 10 and and CC cord-006870-f5w6fw6q 1064 11 II II NNP cord-006870-f5w6fw6q 1064 12 include include VBP cord-006870-f5w6fw6q 1064 13 working work VBG cord-006870-f5w6fw6q 1064 14 alongside alongside IN cord-006870-f5w6fw6q 1064 15 a a DT cord-006870-f5w6fw6q 1064 16 more more RBR cord-006870-f5w6fw6q 1064 17 senior senior JJ cord-006870-f5w6fw6q 1064 18 APP app NN cord-006870-f5w6fw6q 1064 19 preceptor preceptor NN cord-006870-f5w6fw6q 1064 20 and and CC cord-006870-f5w6fw6q 1064 21 providing provide VBG cord-006870-f5w6fw6q 1064 22 bedside bedside NN cord-006870-f5w6fw6q 1064 23 care care NN cord-006870-f5w6fw6q 1064 24 for for IN cord-006870-f5w6fw6q 1064 25 a a DT cord-006870-f5w6fw6q 1064 26 progressively progressively RB cord-006870-f5w6fw6q 1064 27 increasing increase VBG cord-006870-f5w6fw6q 1064 28 number number NN cord-006870-f5w6fw6q 1064 29 of of IN cord-006870-f5w6fw6q 1064 30 patients patient NNS cord-006870-f5w6fw6q 1064 31 . . . cord-006870-f5w6fw6q 1065 1 APPs app NNS cord-006870-f5w6fw6q 1065 2 not not RB cord-006870-f5w6fw6q 1065 3 meeting meet VBG cord-006870-f5w6fw6q 1065 4 minimum minimum NN cord-006870-f5w6fw6q 1065 5 established establish VBN cord-006870-f5w6fw6q 1065 6 standards standard NNS cord-006870-f5w6fw6q 1065 7 on on IN cord-006870-f5w6fw6q 1065 8 any any DT cord-006870-f5w6fw6q 1065 9 aspect aspect NN cord-006870-f5w6fw6q 1065 10 of of IN cord-006870-f5w6fw6q 1065 11 the the DT cord-006870-f5w6fw6q 1065 12 curriculum curriculum NN cord-006870-f5w6fw6q 1065 13 are be VBP cord-006870-f5w6fw6q 1065 14 provided provide VBN cord-006870-f5w6fw6q 1065 15 additional additional JJ cord-006870-f5w6fw6q 1065 16 remediation remediation NN cord-006870-f5w6fw6q 1065 17 and and CC cord-006870-f5w6fw6q 1065 18 instruction instruction NN cord-006870-f5w6fw6q 1065 19 by by IN cord-006870-f5w6fw6q 1065 20 the the DT cord-006870-f5w6fw6q 1065 21 preceptor preceptor NN cord-006870-f5w6fw6q 1065 22 and and CC cord-006870-f5w6fw6q 1065 23 NCC NCC NNP cord-006870-f5w6fw6q 1065 24 faculty faculty NN cord-006870-f5w6fw6q 1065 25 based base VBN cord-006870-f5w6fw6q 1065 26 on on IN cord-006870-f5w6fw6q 1065 27 an an DT cord-006870-f5w6fw6q 1065 28 individualized individualized JJ cord-006870-f5w6fw6q 1065 29 learning learning NN cord-006870-f5w6fw6q 1065 30 plan plan NN cord-006870-f5w6fw6q 1065 31 . . . cord-006870-f5w6fw6q 1066 1 A a DT cord-006870-f5w6fw6q 1066 2 standardized standardized JJ cord-006870-f5w6fw6q 1066 3 educational educational JJ cord-006870-f5w6fw6q 1066 4 curriculum curriculum NN cord-006870-f5w6fw6q 1066 5 provides provide VBZ cord-006870-f5w6fw6q 1066 6 a a DT cord-006870-f5w6fw6q 1066 7 structured structured JJ cord-006870-f5w6fw6q 1066 8 learning learning NN cord-006870-f5w6fw6q 1066 9 environment environment NN cord-006870-f5w6fw6q 1066 10 for for IN cord-006870-f5w6fw6q 1066 11 new new JJ cord-006870-f5w6fw6q 1066 12 APPs app NNS cord-006870-f5w6fw6q 1066 13 in in IN cord-006870-f5w6fw6q 1066 14 the the DT cord-006870-f5w6fw6q 1066 15 field field NN cord-006870-f5w6fw6q 1066 16 of of IN cord-006870-f5w6fw6q 1066 17 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1066 18 care care NN cord-006870-f5w6fw6q 1066 19 . . . cord-006870-f5w6fw6q 1067 1 Reimbursement reimbursement NN cord-006870-f5w6fw6q 1067 2 changes change NNS cord-006870-f5w6fw6q 1067 3 from from IN cord-006870-f5w6fw6q 1067 4 the the DT cord-006870-f5w6fw6q 1067 5 Centers Centers NNPS cord-006870-f5w6fw6q 1067 6 for for IN cord-006870-f5w6fw6q 1067 7 Medicare Medicare NNP cord-006870-f5w6fw6q 1067 8 and and CC cord-006870-f5w6fw6q 1067 9 Medicaid Medicaid NNP cord-006870-f5w6fw6q 1067 10 Services Services NNPS cord-006870-f5w6fw6q 1067 11 and and CC cord-006870-f5w6fw6q 1067 12 value value NN cord-006870-f5w6fw6q 1067 13 based base VBN cord-006870-f5w6fw6q 1067 14 purchasing purchasing NN cord-006870-f5w6fw6q 1067 15 systems system NNS cord-006870-f5w6fw6q 1067 16 have have VBP cord-006870-f5w6fw6q 1067 17 made make VBN cord-006870-f5w6fw6q 1067 18 quality quality NN cord-006870-f5w6fw6q 1067 19 improvement improvement NN cord-006870-f5w6fw6q 1067 20 linked link VBN cord-006870-f5w6fw6q 1067 21 to to IN cord-006870-f5w6fw6q 1067 22 clinical clinical JJ cord-006870-f5w6fw6q 1067 23 outcomes outcome NNS cord-006870-f5w6fw6q 1067 24 more more RBR cord-006870-f5w6fw6q 1067 25 crucial crucial JJ cord-006870-f5w6fw6q 1067 26 than than IN cord-006870-f5w6fw6q 1067 27 ever ever RB cord-006870-f5w6fw6q 1067 28 . . . cord-006870-f5w6fw6q 1068 1 In in IN cord-006870-f5w6fw6q 1068 2 one one CD cord-006870-f5w6fw6q 1068 3 neuroscience neuroscience NN cord-006870-f5w6fw6q 1068 4 ICU ICU NNP cord-006870-f5w6fw6q 1068 5 , , , cord-006870-f5w6fw6q 1068 6 providers provider NNS cord-006870-f5w6fw6q 1068 7 and and CC cord-006870-f5w6fw6q 1068 8 nurses nurse NNS cord-006870-f5w6fw6q 1068 9 collaborate collaborate VBP cord-006870-f5w6fw6q 1068 10 to to TO cord-006870-f5w6fw6q 1068 11 address address VB cord-006870-f5w6fw6q 1068 12 key key JJ cord-006870-f5w6fw6q 1068 13 infection infection NN cord-006870-f5w6fw6q 1068 14 parameters parameter VBZ cord-006870-f5w6fw6q 1068 15 that that IN cord-006870-f5w6fw6q 1068 16 impact impact NN cord-006870-f5w6fw6q 1068 17 patient patient NN cord-006870-f5w6fw6q 1068 18 outcomes outcome NNS cord-006870-f5w6fw6q 1068 19 . . . cord-006870-f5w6fw6q 1069 1 Quality quality JJ cord-006870-f5w6fw6q 1069 2 metric metric JJ cord-006870-f5w6fw6q 1069 3 data datum NNS cord-006870-f5w6fw6q 1069 4 in in IN cord-006870-f5w6fw6q 1069 5 one one CD cord-006870-f5w6fw6q 1069 6 neuroscience neuroscience NN cord-006870-f5w6fw6q 1069 7 ICU ICU NNP cord-006870-f5w6fw6q 1069 8 was be VBD cord-006870-f5w6fw6q 1069 9 collected collect VBN cord-006870-f5w6fw6q 1069 10 over over IN cord-006870-f5w6fw6q 1069 11 a a DT cord-006870-f5w6fw6q 1069 12 period period NN cord-006870-f5w6fw6q 1069 13 of of IN cord-006870-f5w6fw6q 1069 14 3 3 CD cord-006870-f5w6fw6q 1069 15 fiscal fiscal JJ cord-006870-f5w6fw6q 1069 16 years year NNS cord-006870-f5w6fw6q 1069 17 . . . cord-006870-f5w6fw6q 1070 1 Outcome outcome NN cord-006870-f5w6fw6q 1070 2 measures measure NNS cord-006870-f5w6fw6q 1070 3 , , , cord-006870-f5w6fw6q 1070 4 consisting consist VBG cord-006870-f5w6fw6q 1070 5 of of IN cord-006870-f5w6fw6q 1070 6 glycemic glycemic NN cord-006870-f5w6fw6q 1070 7 and and CC cord-006870-f5w6fw6q 1070 8 temperature temperature NN cord-006870-f5w6fw6q 1070 9 control control NN cord-006870-f5w6fw6q 1070 10 , , , cord-006870-f5w6fw6q 1070 11 and and CC cord-006870-f5w6fw6q 1070 12 ventilator ventilator NN cord-006870-f5w6fw6q 1070 13 weaning weaning NN cord-006870-f5w6fw6q 1070 14 strategies strategy NNS cord-006870-f5w6fw6q 1070 15 , , , cord-006870-f5w6fw6q 1070 16 were be VBD cord-006870-f5w6fw6q 1070 17 obtained obtain VBN cord-006870-f5w6fw6q 1070 18 after after IN cord-006870-f5w6fw6q 1070 19 certain certain JJ cord-006870-f5w6fw6q 1070 20 parameters parameter NNS cord-006870-f5w6fw6q 1070 21 were be VBD cord-006870-f5w6fw6q 1070 22 enforced enforce VBN cord-006870-f5w6fw6q 1070 23 over over IN cord-006870-f5w6fw6q 1070 24 two two CD cord-006870-f5w6fw6q 1070 25 years year NNS cord-006870-f5w6fw6q 1070 26 and and CC cord-006870-f5w6fw6q 1070 27 then then RB cord-006870-f5w6fw6q 1070 28 compared compare VBN cord-006870-f5w6fw6q 1070 29 to to IN cord-006870-f5w6fw6q 1070 30 the the DT cord-006870-f5w6fw6q 1070 31 initial initial JJ cord-006870-f5w6fw6q 1070 32 year year NN cord-006870-f5w6fw6q 1070 33 . . . cord-006870-f5w6fw6q 1071 1 The the DT cord-006870-f5w6fw6q 1071 2 urinary urinary JJ cord-006870-f5w6fw6q 1071 3 catheter catheter NN cord-006870-f5w6fw6q 1071 4 utilization utilization NN cord-006870-f5w6fw6q 1071 5 has have VBZ cord-006870-f5w6fw6q 1071 6 decreased decrease VBN cord-006870-f5w6fw6q 1071 7 by by IN cord-006870-f5w6fw6q 1071 8 over over IN cord-006870-f5w6fw6q 1071 9 10 10 CD cord-006870-f5w6fw6q 1071 10 % % NN cord-006870-f5w6fw6q 1071 11 , , , cord-006870-f5w6fw6q 1071 12 with with IN cord-006870-f5w6fw6q 1071 13 catheter catheter NN cord-006870-f5w6fw6q 1071 14 associated associate VBD cord-006870-f5w6fw6q 1071 15 urinary urinary JJ cord-006870-f5w6fw6q 1071 16 tract tract NN cord-006870-f5w6fw6q 1071 17 infections infection NNS cord-006870-f5w6fw6q 1071 18 decreased decrease VBD cord-006870-f5w6fw6q 1071 19 by by IN cord-006870-f5w6fw6q 1071 20 80 80 CD cord-006870-f5w6fw6q 1071 21 % % NN cord-006870-f5w6fw6q 1071 22 in in IN cord-006870-f5w6fw6q 1071 23 3 3 CD cord-006870-f5w6fw6q 1071 24 years year NNS cord-006870-f5w6fw6q 1071 25 ( ( -LRB- cord-006870-f5w6fw6q 1071 26 p p NN cord-006870-f5w6fw6q 1071 27 - - HYPH cord-006870-f5w6fw6q 1071 28 value value NN cord-006870-f5w6fw6q 1071 29 < < XX cord-006870-f5w6fw6q 1071 30 0.0001 0.0001 CD cord-006870-f5w6fw6q 1071 31 ) ) -RRB- cord-006870-f5w6fw6q 1071 32 . . . cord-006870-f5w6fw6q 1072 1 Central central JJ cord-006870-f5w6fw6q 1072 2 line line NN cord-006870-f5w6fw6q 1072 3 utilization utilization NN cord-006870-f5w6fw6q 1072 4 decreased decrease VBD cord-006870-f5w6fw6q 1072 5 by by IN cord-006870-f5w6fw6q 1072 6 5 5 CD cord-006870-f5w6fw6q 1072 7 % % NN cord-006870-f5w6fw6q 1072 8 , , , cord-006870-f5w6fw6q 1072 9 with with IN cord-006870-f5w6fw6q 1072 10 a a DT cord-006870-f5w6fw6q 1072 11 60 60 CD cord-006870-f5w6fw6q 1072 12 % % NN cord-006870-f5w6fw6q 1072 13 decrease decrease NN cord-006870-f5w6fw6q 1072 14 in in IN cord-006870-f5w6fw6q 1072 15 central central JJ cord-006870-f5w6fw6q 1072 16 line line NN cord-006870-f5w6fw6q 1072 17 associated associate VBN cord-006870-f5w6fw6q 1072 18 blood blood NN cord-006870-f5w6fw6q 1072 19 stream stream NN cord-006870-f5w6fw6q 1072 20 infections infection NNS cord-006870-f5w6fw6q 1072 21 in in IN cord-006870-f5w6fw6q 1072 22 3 3 CD cord-006870-f5w6fw6q 1072 23 years year NNS cord-006870-f5w6fw6q 1072 24 ( ( -LRB- cord-006870-f5w6fw6q 1072 25 p p NN cord-006870-f5w6fw6q 1072 26 - - HYPH cord-006870-f5w6fw6q 1072 27 value value NN cord-006870-f5w6fw6q 1072 28 0.45 0.45 CD cord-006870-f5w6fw6q 1072 29 ) ) -RRB- cord-006870-f5w6fw6q 1072 30 . . . cord-006870-f5w6fw6q 1073 1 New new JJ cord-006870-f5w6fw6q 1073 2 ventilator ventilator NN cord-006870-f5w6fw6q 1073 3 weaning wean VBG cord-006870-f5w6fw6q 1073 4 strategies strategy NNS cord-006870-f5w6fw6q 1073 5 were be VBD cord-006870-f5w6fw6q 1073 6 put put VBN cord-006870-f5w6fw6q 1073 7 into into IN cord-006870-f5w6fw6q 1073 8 place place NN cord-006870-f5w6fw6q 1073 9 utilizing utilize VBG cord-006870-f5w6fw6q 1073 10 adaptive adaptive JJ cord-006870-f5w6fw6q 1073 11 support support NN cord-006870-f5w6fw6q 1073 12 ventilation ventilation NN cord-006870-f5w6fw6q 1073 13 mode mode NN cord-006870-f5w6fw6q 1073 14 , , , cord-006870-f5w6fw6q 1073 15 which which WDT cord-006870-f5w6fw6q 1073 16 decreased decrease VBD cord-006870-f5w6fw6q 1073 17 total total JJ cord-006870-f5w6fw6q 1073 18 ventilator ventilator NN cord-006870-f5w6fw6q 1073 19 days day NNS cord-006870-f5w6fw6q 1073 20 by by IN cord-006870-f5w6fw6q 1073 21 1000 1000 CD cord-006870-f5w6fw6q 1073 22 days day NNS cord-006870-f5w6fw6q 1073 23 / / SYM cord-006870-f5w6fw6q 1073 24 year year NN cord-006870-f5w6fw6q 1073 25 . . . cord-006870-f5w6fw6q 1074 1 Successful successful JJ cord-006870-f5w6fw6q 1074 2 weaning weaning NN cord-006870-f5w6fw6q 1074 3 and and CC cord-006870-f5w6fw6q 1074 4 extubations extubation NNS cord-006870-f5w6fw6q 1074 5 resulted result VBD cord-006870-f5w6fw6q 1074 6 in in IN cord-006870-f5w6fw6q 1074 7 no no DT cord-006870-f5w6fw6q 1074 8 recorded record VBN cord-006870-f5w6fw6q 1074 9 ventilator ventilator NN cord-006870-f5w6fw6q 1074 10 - - HYPH cord-006870-f5w6fw6q 1074 11 associated associate VBN cord-006870-f5w6fw6q 1074 12 pneumonia pneumonia NN cord-006870-f5w6fw6q 1074 13 in in IN cord-006870-f5w6fw6q 1074 14 the the DT cord-006870-f5w6fw6q 1074 15 last last JJ cord-006870-f5w6fw6q 1074 16 3 3 CD cord-006870-f5w6fw6q 1074 17 years year NNS cord-006870-f5w6fw6q 1074 18 . . . cord-006870-f5w6fw6q 1075 1 This this DT cord-006870-f5w6fw6q 1075 2 neuroscience neuroscience NN cord-006870-f5w6fw6q 1075 3 ICU ICU NNP cord-006870-f5w6fw6q 1075 4 maintains maintain VBZ cord-006870-f5w6fw6q 1075 5 glucose glucose NN cord-006870-f5w6fw6q 1075 6 below below IN cord-006870-f5w6fw6q 1075 7 180mg 180mg NNP cord-006870-f5w6fw6q 1075 8 / / SYM cord-006870-f5w6fw6q 1075 9 dl dl NN cord-006870-f5w6fw6q 1075 10 more more JJR cord-006870-f5w6fw6q 1075 11 than than IN cord-006870-f5w6fw6q 1075 12 85 85 CD cord-006870-f5w6fw6q 1075 13 % % NN cord-006870-f5w6fw6q 1075 14 of of IN cord-006870-f5w6fw6q 1075 15 the the DT cord-006870-f5w6fw6q 1075 16 time time NN cord-006870-f5w6fw6q 1075 17 . . . cord-006870-f5w6fw6q 1076 1 Regarding regard VBG cord-006870-f5w6fw6q 1076 2 temperature temperature NN cord-006870-f5w6fw6q 1076 3 control control NN cord-006870-f5w6fw6q 1076 4 data datum NNS cord-006870-f5w6fw6q 1076 5 , , , cord-006870-f5w6fw6q 1076 6 a a DT cord-006870-f5w6fw6q 1076 7 normothermia normothermia NN cord-006870-f5w6fw6q 1076 8 protocol protocol NN cord-006870-f5w6fw6q 1076 9 was be VBD cord-006870-f5w6fw6q 1076 10 implemented implement VBN cord-006870-f5w6fw6q 1076 11 that that WDT cord-006870-f5w6fw6q 1076 12 utilizes utilize VBZ cord-006870-f5w6fw6q 1076 13 aggressive aggressive JJ cord-006870-f5w6fw6q 1076 14 temperature temperature NN cord-006870-f5w6fw6q 1076 15 control control NN cord-006870-f5w6fw6q 1076 16 coupled couple VBN cord-006870-f5w6fw6q 1076 17 with with IN cord-006870-f5w6fw6q 1076 18 bromocriptine bromocriptine NNP cord-006870-f5w6fw6q 1076 19 administration administration NN cord-006870-f5w6fw6q 1076 20 . . . cord-006870-f5w6fw6q 1077 1 As as IN cord-006870-f5w6fw6q 1077 2 a a DT cord-006870-f5w6fw6q 1077 3 result result NN cord-006870-f5w6fw6q 1077 4 , , , cord-006870-f5w6fw6q 1077 5 95 95 CD cord-006870-f5w6fw6q 1077 6 % % NN cord-006870-f5w6fw6q 1077 7 of of IN cord-006870-f5w6fw6q 1077 8 patients patient NNS cord-006870-f5w6fw6q 1077 9 had have VBD cord-006870-f5w6fw6q 1077 10 a a DT cord-006870-f5w6fw6q 1077 11 temperature temperature NN cord-006870-f5w6fw6q 1077 12 less less JJR cord-006870-f5w6fw6q 1077 13 than than IN cord-006870-f5w6fw6q 1077 14 38 38 CD cord-006870-f5w6fw6q 1077 15 ° ° NN cord-006870-f5w6fw6q 1077 16 C c NN cord-006870-f5w6fw6q 1077 17 . . . cord-006870-f5w6fw6q 1078 1 All all DT cord-006870-f5w6fw6q 1078 2 of of IN cord-006870-f5w6fw6q 1078 3 the the DT cord-006870-f5w6fw6q 1078 4 quality quality NN cord-006870-f5w6fw6q 1078 5 initiatives initiative NNS cord-006870-f5w6fw6q 1078 6 that that WDT cord-006870-f5w6fw6q 1078 7 have have VBP cord-006870-f5w6fw6q 1078 8 been be VBN cord-006870-f5w6fw6q 1078 9 implemented implement VBN cord-006870-f5w6fw6q 1078 10 have have VBP cord-006870-f5w6fw6q 1078 11 improved improve VBN cord-006870-f5w6fw6q 1078 12 the the DT cord-006870-f5w6fw6q 1078 13 observed observed JJ cord-006870-f5w6fw6q 1078 14 / / SYM cord-006870-f5w6fw6q 1078 15 expected expect VBN cord-006870-f5w6fw6q 1078 16 mortality mortality NN cord-006870-f5w6fw6q 1078 17 ratio ratio NN cord-006870-f5w6fw6q 1078 18 by by IN cord-006870-f5w6fw6q 1078 19 4.4 4.4 CD cord-006870-f5w6fw6q 1078 20 % % NN cord-006870-f5w6fw6q 1078 21 . . . cord-006870-f5w6fw6q 1079 1 This this DT cord-006870-f5w6fw6q 1079 2 study study NN cord-006870-f5w6fw6q 1079 3 shows show VBZ cord-006870-f5w6fw6q 1079 4 that that IN cord-006870-f5w6fw6q 1079 5 by by IN cord-006870-f5w6fw6q 1079 6 optimizing optimize VBG cord-006870-f5w6fw6q 1079 7 infection infection NN cord-006870-f5w6fw6q 1079 8 control control NN cord-006870-f5w6fw6q 1079 9 , , , cord-006870-f5w6fw6q 1079 10 temperature temperature NN cord-006870-f5w6fw6q 1079 11 management management NN cord-006870-f5w6fw6q 1079 12 , , , cord-006870-f5w6fw6q 1079 13 glycemic glycemic NN cord-006870-f5w6fw6q 1079 14 control control NN cord-006870-f5w6fw6q 1079 15 and and CC cord-006870-f5w6fw6q 1079 16 ventilation ventilation NN cord-006870-f5w6fw6q 1079 17 strategies strategy NNS cord-006870-f5w6fw6q 1079 18 , , , cord-006870-f5w6fw6q 1079 19 there there EX cord-006870-f5w6fw6q 1079 20 is be VBZ cord-006870-f5w6fw6q 1079 21 an an DT cord-006870-f5w6fw6q 1079 22 overall overall JJ cord-006870-f5w6fw6q 1079 23 positive positive JJ cord-006870-f5w6fw6q 1079 24 impact impact NN cord-006870-f5w6fw6q 1079 25 on on IN cord-006870-f5w6fw6q 1079 26 the the DT cord-006870-f5w6fw6q 1079 27 patient patient NN cord-006870-f5w6fw6q 1079 28 's 's POS cord-006870-f5w6fw6q 1079 29 morbidity morbidity NN cord-006870-f5w6fw6q 1079 30 and and CC cord-006870-f5w6fw6q 1079 31 mortality mortality NN cord-006870-f5w6fw6q 1079 32 . . . cord-006870-f5w6fw6q 1080 1 As as IN cord-006870-f5w6fw6q 1080 2 evidenced evidence VBN cord-006870-f5w6fw6q 1080 3 by by IN cord-006870-f5w6fw6q 1080 4 these these DT cord-006870-f5w6fw6q 1080 5 results result NNS cord-006870-f5w6fw6q 1080 6 , , , cord-006870-f5w6fw6q 1080 7 this this DT cord-006870-f5w6fw6q 1080 8 institution institution NN cord-006870-f5w6fw6q 1080 9 is be VBZ cord-006870-f5w6fw6q 1080 10 now now RB cord-006870-f5w6fw6q 1080 11 a a DT cord-006870-f5w6fw6q 1080 12 top top JJ cord-006870-f5w6fw6q 1080 13 performer performer NN cord-006870-f5w6fw6q 1080 14 when when WRB cord-006870-f5w6fw6q 1080 15 compared compare VBN cord-006870-f5w6fw6q 1080 16 in in IN cord-006870-f5w6fw6q 1080 17 a a DT cord-006870-f5w6fw6q 1080 18 national national JJ cord-006870-f5w6fw6q 1080 19 clinical clinical JJ cord-006870-f5w6fw6q 1080 20 database database NN cord-006870-f5w6fw6q 1080 21 . . . cord-006870-f5w6fw6q 1081 1 This this DT cord-006870-f5w6fw6q 1081 2 presentation presentation NN cord-006870-f5w6fw6q 1081 3 will will MD cord-006870-f5w6fw6q 1081 4 share share VB cord-006870-f5w6fw6q 1081 5 the the DT cord-006870-f5w6fw6q 1081 6 pragmatic pragmatic JJ cord-006870-f5w6fw6q 1081 7 strategies strategy NNS cord-006870-f5w6fw6q 1081 8 to to TO cord-006870-f5w6fw6q 1081 9 create create VB cord-006870-f5w6fw6q 1081 10 a a DT cord-006870-f5w6fw6q 1081 11 culture culture NN cord-006870-f5w6fw6q 1081 12 of of IN cord-006870-f5w6fw6q 1081 13 quality quality NN cord-006870-f5w6fw6q 1081 14 improvement improvement NN cord-006870-f5w6fw6q 1081 15 in in IN cord-006870-f5w6fw6q 1081 16 any any DT cord-006870-f5w6fw6q 1081 17 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1081 18 care care NN cord-006870-f5w6fw6q 1081 19 unit unit NN cord-006870-f5w6fw6q 1081 20 or or CC cord-006870-f5w6fw6q 1081 21 patient patient NN cord-006870-f5w6fw6q 1081 22 care care NN cord-006870-f5w6fw6q 1081 23 organization organization NN cord-006870-f5w6fw6q 1081 24 . . . cord-006870-f5w6fw6q 1082 1 Health health NN cord-006870-f5w6fw6q 1082 2 care care NN cord-006870-f5w6fw6q 1082 3 records record NNS cord-006870-f5w6fw6q 1082 4 are be VBP cord-006870-f5w6fw6q 1082 5 not not RB cord-006870-f5w6fw6q 1082 6 accessible accessible JJ cord-006870-f5w6fw6q 1082 7 universally universally RB cord-006870-f5w6fw6q 1082 8 at at IN cord-006870-f5w6fw6q 1082 9 point point NN cord-006870-f5w6fw6q 1082 10 of of IN cord-006870-f5w6fw6q 1082 11 care care NN cord-006870-f5w6fw6q 1082 12 delivery delivery NN cord-006870-f5w6fw6q 1082 13 . . . cord-006870-f5w6fw6q 1083 1 In in IN cord-006870-f5w6fw6q 1083 2 developing develop VBG cord-006870-f5w6fw6q 1083 3 countries country NNS cord-006870-f5w6fw6q 1083 4 like like IN cord-006870-f5w6fw6q 1083 5 Thailand Thailand NNP cord-006870-f5w6fw6q 1083 6 a a DT cord-006870-f5w6fw6q 1083 7 large large JJ cord-006870-f5w6fw6q 1083 8 proportion proportion NN cord-006870-f5w6fw6q 1083 9 of of IN cord-006870-f5w6fw6q 1083 10 health health NN cord-006870-f5w6fw6q 1083 11 care care NN cord-006870-f5w6fw6q 1083 12 records record NNS cord-006870-f5w6fw6q 1083 13 are be VBP cord-006870-f5w6fw6q 1083 14 still still RB cord-006870-f5w6fw6q 1083 15 paper paper NN cord-006870-f5w6fw6q 1083 16 based base VBN cord-006870-f5w6fw6q 1083 17 . . . cord-006870-f5w6fw6q 1084 1 Patients patient NNS cord-006870-f5w6fw6q 1084 2 may may MD cord-006870-f5w6fw6q 1084 3 not not RB cord-006870-f5w6fw6q 1084 4 able able JJ cord-006870-f5w6fw6q 1084 5 to to TO cord-006870-f5w6fw6q 1084 6 convey convey VB cord-006870-f5w6fw6q 1084 7 relevant relevant JJ cord-006870-f5w6fw6q 1084 8 information information NN cord-006870-f5w6fw6q 1084 9 about about IN cord-006870-f5w6fw6q 1084 10 their -PRON- PRP$ cord-006870-f5w6fw6q 1084 11 own own JJ cord-006870-f5w6fw6q 1084 12 medical medical JJ cord-006870-f5w6fw6q 1084 13 problems problem NNS cord-006870-f5w6fw6q 1084 14 and and CC cord-006870-f5w6fw6q 1084 15 medications medication NNS cord-006870-f5w6fw6q 1084 16 during during IN cord-006870-f5w6fw6q 1084 17 patient patient NN cord-006870-f5w6fw6q 1084 18 - - HYPH cord-006870-f5w6fw6q 1084 19 physician physician NN cord-006870-f5w6fw6q 1084 20 encounters encounter NNS cord-006870-f5w6fw6q 1084 21 or or CC cord-006870-f5w6fw6q 1084 22 in in IN cord-006870-f5w6fw6q 1084 23 the the DT cord-006870-f5w6fw6q 1084 24 event event NN cord-006870-f5w6fw6q 1084 25 of of IN cord-006870-f5w6fw6q 1084 26 emergency emergency NN cord-006870-f5w6fw6q 1084 27 . . . cord-006870-f5w6fw6q 1085 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1085 2 purpose purpose NN cord-006870-f5w6fw6q 1085 3 was be VBD cord-006870-f5w6fw6q 1085 4 to to TO cord-006870-f5w6fw6q 1085 5 create create VB cord-006870-f5w6fw6q 1085 6 a a DT cord-006870-f5w6fw6q 1085 7 simple simple JJ cord-006870-f5w6fw6q 1085 8 platform platform NN cord-006870-f5w6fw6q 1085 9 for for IN cord-006870-f5w6fw6q 1085 10 recording record VBG cord-006870-f5w6fw6q 1085 11 relevant relevant JJ cord-006870-f5w6fw6q 1085 12 basic basic JJ cord-006870-f5w6fw6q 1085 13 healthcare healthcare NN cord-006870-f5w6fw6q 1085 14 information information NN cord-006870-f5w6fw6q 1085 15 through through IN cord-006870-f5w6fw6q 1085 16 a a DT cord-006870-f5w6fw6q 1085 17 system system NN cord-006870-f5w6fw6q 1085 18 that that WDT cord-006870-f5w6fw6q 1085 19 can can MD cord-006870-f5w6fw6q 1085 20 be be VB cord-006870-f5w6fw6q 1085 21 securely securely RB cord-006870-f5w6fw6q 1085 22 accessed access VBN cord-006870-f5w6fw6q 1085 23 even even RB cord-006870-f5w6fw6q 1085 24 in in IN cord-006870-f5w6fw6q 1085 25 countries country NNS cord-006870-f5w6fw6q 1085 26 like like IN cord-006870-f5w6fw6q 1085 27 Thailand Thailand NNP cord-006870-f5w6fw6q 1085 28 . . . cord-006870-f5w6fw6q 1086 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1086 2 vision vision NN cord-006870-f5w6fw6q 1086 3 is be VBZ cord-006870-f5w6fw6q 1086 4 to to TO cord-006870-f5w6fw6q 1086 5 improve improve VB cord-006870-f5w6fw6q 1086 6 healthcare healthcare NN cord-006870-f5w6fw6q 1086 7 communications communication NNS cord-006870-f5w6fw6q 1086 8 and and CC cord-006870-f5w6fw6q 1086 9 leverage leverage VB cord-006870-f5w6fw6q 1086 10 social social JJ cord-006870-f5w6fw6q 1086 11 media medium NNS cord-006870-f5w6fw6q 1086 12 in in IN cord-006870-f5w6fw6q 1086 13 Thailand Thailand NNP cord-006870-f5w6fw6q 1086 14 and and CC cord-006870-f5w6fw6q 1086 15 other other JJ cord-006870-f5w6fw6q 1086 16 developing develop VBG cord-006870-f5w6fw6q 1086 17 countries country NNS cord-006870-f5w6fw6q 1086 18 , , , cord-006870-f5w6fw6q 1086 19 particularly particularly RB cord-006870-f5w6fw6q 1086 20 for for IN cord-006870-f5w6fw6q 1086 21 patients patient NNS cord-006870-f5w6fw6q 1086 22 with with IN cord-006870-f5w6fw6q 1086 23 lower low JJR cord-006870-f5w6fw6q 1086 24 levels level NNS cord-006870-f5w6fw6q 1086 25 of of IN cord-006870-f5w6fw6q 1086 26 education education NN cord-006870-f5w6fw6q 1086 27 or or CC cord-006870-f5w6fw6q 1086 28 socioeconomic socioeconomic JJ cord-006870-f5w6fw6q 1086 29 status status NN cord-006870-f5w6fw6q 1086 30 . . . cord-006870-f5w6fw6q 1087 1 We -PRON- PRP cord-006870-f5w6fw6q 1087 2 created create VBD cord-006870-f5w6fw6q 1087 3 a a DT cord-006870-f5w6fw6q 1087 4 cloud cloud NN cord-006870-f5w6fw6q 1087 5 - - HYPH cord-006870-f5w6fw6q 1087 6 based base VBN cord-006870-f5w6fw6q 1087 7 personal personal JJ cord-006870-f5w6fw6q 1087 8 healthcare healthcare NN cord-006870-f5w6fw6q 1087 9 information information NN cord-006870-f5w6fw6q 1087 10 platform platform NN cord-006870-f5w6fw6q 1087 11 ' ' `` cord-006870-f5w6fw6q 1087 12 MEiD MEiD NNP cord-006870-f5w6fw6q 1087 13 ' ' '' cord-006870-f5w6fw6q 1087 14 that that WDT cord-006870-f5w6fw6q 1087 15 uses use VBZ cord-006870-f5w6fw6q 1087 16 a a DT cord-006870-f5w6fw6q 1087 17 QR qr NN cord-006870-f5w6fw6q 1087 18 code code NN cord-006870-f5w6fw6q 1087 19 scanned scan VBN cord-006870-f5w6fw6q 1087 20 from from IN cord-006870-f5w6fw6q 1087 21 wristbands wristband NNS cord-006870-f5w6fw6q 1087 22 and and CC cord-006870-f5w6fw6q 1087 23 other other JJ cord-006870-f5w6fw6q 1087 24 products product NNS cord-006870-f5w6fw6q 1087 25 like like IN cord-006870-f5w6fw6q 1087 26 stickers sticker NNS cord-006870-f5w6fw6q 1087 27 to to TO cord-006870-f5w6fw6q 1087 28 access access VB cord-006870-f5w6fw6q 1087 29 patient patient JJ cord-006870-f5w6fw6q 1087 30 information information NN cord-006870-f5w6fw6q 1087 31 . . . cord-006870-f5w6fw6q 1088 1 Conventional conventional JJ cord-006870-f5w6fw6q 1088 2 methods method NNS cord-006870-f5w6fw6q 1088 3 require require VBP cord-006870-f5w6fw6q 1088 4 a a DT cord-006870-f5w6fw6q 1088 5 treating treat VBG cord-006870-f5w6fw6q 1088 6 team team NN cord-006870-f5w6fw6q 1088 7 to to TO cord-006870-f5w6fw6q 1088 8 request request VB cord-006870-f5w6fw6q 1088 9 medical medical JJ cord-006870-f5w6fw6q 1088 10 records record NNS cord-006870-f5w6fw6q 1088 11 from from IN cord-006870-f5w6fw6q 1088 12 a a DT cord-006870-f5w6fw6q 1088 13 patients patient NNS cord-006870-f5w6fw6q 1088 14 ' ' POS cord-006870-f5w6fw6q 1088 15 prior prior JJ cord-006870-f5w6fw6q 1088 16 hospital hospital NN cord-006870-f5w6fw6q 1088 17 visits visit NNS cord-006870-f5w6fw6q 1088 18 including include VBG cord-006870-f5w6fw6q 1088 19 visits visit NNS cord-006870-f5w6fw6q 1088 20 at at IN cord-006870-f5w6fw6q 1088 21 different different JJ cord-006870-f5w6fw6q 1088 22 medical medical JJ cord-006870-f5w6fw6q 1088 23 facilities facility NNS cord-006870-f5w6fw6q 1088 24 . . . cord-006870-f5w6fw6q 1089 1 Time time NN cord-006870-f5w6fw6q 1089 2 lost lose VBN cord-006870-f5w6fw6q 1089 3 during during IN cord-006870-f5w6fw6q 1089 4 this this DT cord-006870-f5w6fw6q 1089 5 process process NN cord-006870-f5w6fw6q 1089 6 can can MD cord-006870-f5w6fw6q 1089 7 potentially potentially RB cord-006870-f5w6fw6q 1089 8 cause cause VB cord-006870-f5w6fw6q 1089 9 delay delay NN cord-006870-f5w6fw6q 1089 10 in in IN cord-006870-f5w6fw6q 1089 11 treatment treatment NN cord-006870-f5w6fw6q 1089 12 decisions decision NNS cord-006870-f5w6fw6q 1089 13 . . . cord-006870-f5w6fw6q 1090 1 We -PRON- PRP cord-006870-f5w6fw6q 1090 2 also also RB cord-006870-f5w6fw6q 1090 3 aim aim VBP cord-006870-f5w6fw6q 1090 4 to to TO cord-006870-f5w6fw6q 1090 5 improve improve VB cord-006870-f5w6fw6q 1090 6 health health NN cord-006870-f5w6fw6q 1090 7 literacy literacy NN cord-006870-f5w6fw6q 1090 8 in in IN cord-006870-f5w6fw6q 1090 9 Thailand Thailand NNP cord-006870-f5w6fw6q 1090 10 . . . cord-006870-f5w6fw6q 1091 1 Application application NN cord-006870-f5w6fw6q 1091 2 name name NN cord-006870-f5w6fw6q 1091 3 ' ' `` cord-006870-f5w6fw6q 1091 4 MEiDTH MEiDTH NNP cord-006870-f5w6fw6q 1091 5 ' ' '' cord-006870-f5w6fw6q 1091 6 is be VBZ cord-006870-f5w6fw6q 1091 7 available available JJ cord-006870-f5w6fw6q 1091 8 in in IN cord-006870-f5w6fw6q 1091 9 both both DT cord-006870-f5w6fw6q 1091 10 apple apple NN cord-006870-f5w6fw6q 1091 11 store store NN cord-006870-f5w6fw6q 1091 12 and and CC cord-006870-f5w6fw6q 1091 13 google google NNP cord-006870-f5w6fw6q 1091 14 play play VBP cord-006870-f5w6fw6q 1091 15 . . . cord-006870-f5w6fw6q 1092 1 We -PRON- PRP cord-006870-f5w6fw6q 1092 2 launched launch VBD cord-006870-f5w6fw6q 1092 3 MEiD MEiD NNP cord-006870-f5w6fw6q 1092 4 in in IN cord-006870-f5w6fw6q 1092 5 Thailand Thailand NNP cord-006870-f5w6fw6q 1092 6 in in IN cord-006870-f5w6fw6q 1092 7 April April NNP cord-006870-f5w6fw6q 1092 8 of of IN cord-006870-f5w6fw6q 1092 9 2017 2017 CD cord-006870-f5w6fw6q 1092 10 . . . cord-006870-f5w6fw6q 1093 1 We -PRON- PRP cord-006870-f5w6fw6q 1093 2 have have VBP cord-006870-f5w6fw6q 1093 3 more more JJR cord-006870-f5w6fw6q 1093 4 than than IN cord-006870-f5w6fw6q 1093 5 1,000 1,000 CD cord-006870-f5w6fw6q 1093 6 active active JJ cord-006870-f5w6fw6q 1093 7 users user NNS cord-006870-f5w6fw6q 1093 8 and and CC cord-006870-f5w6fw6q 1093 9 have have VBP cord-006870-f5w6fw6q 1093 10 sold sell VBN cord-006870-f5w6fw6q 1093 11 more more JJR cord-006870-f5w6fw6q 1093 12 than than IN cord-006870-f5w6fw6q 1093 13 3000 3000 CD cord-006870-f5w6fw6q 1093 14 wristbands wristband NNS cord-006870-f5w6fw6q 1093 15 . . . cord-006870-f5w6fw6q 1094 1 The the DT cord-006870-f5w6fw6q 1094 2 MEiD MEiD NNP cord-006870-f5w6fw6q 1094 3 Thailand Thailand NNP cord-006870-f5w6fw6q 1094 4 Facebook Facebook NNP cord-006870-f5w6fw6q 1094 5 page page NN cord-006870-f5w6fw6q 1094 6 has have VBZ cord-006870-f5w6fw6q 1094 7 received receive VBN cord-006870-f5w6fw6q 1094 8 20,367 20,367 CD cord-006870-f5w6fw6q 1094 9 likes like NNS cord-006870-f5w6fw6q 1094 10 . . . cord-006870-f5w6fw6q 1095 1 There there EX cord-006870-f5w6fw6q 1095 2 are be VBP cord-006870-f5w6fw6q 1095 3 at at RB cord-006870-f5w6fw6q 1095 4 least least RBS cord-006870-f5w6fw6q 1095 5 two two CD cord-006870-f5w6fw6q 1095 6 patients patient NNS cord-006870-f5w6fw6q 1095 7 that that WDT cord-006870-f5w6fw6q 1095 8 have have VBP cord-006870-f5w6fw6q 1095 9 already already RB cord-006870-f5w6fw6q 1095 10 benefited benefit VBN cord-006870-f5w6fw6q 1095 11 from from IN cord-006870-f5w6fw6q 1095 12 this this DT cord-006870-f5w6fw6q 1095 13 product product NN cord-006870-f5w6fw6q 1095 14 : : : cord-006870-f5w6fw6q 1095 15 one one CD cord-006870-f5w6fw6q 1095 16 of of IN cord-006870-f5w6fw6q 1095 17 these these DT cord-006870-f5w6fw6q 1095 18 patients patient NNS cord-006870-f5w6fw6q 1095 19 received receive VBD cord-006870-f5w6fw6q 1095 20 intravenous intravenous JJ cord-006870-f5w6fw6q 1095 21 tissue tissue NN cord-006870-f5w6fw6q 1095 22 plasminogen plasminogen NN cord-006870-f5w6fw6q 1095 23 and and CC cord-006870-f5w6fw6q 1095 24 had have VBD cord-006870-f5w6fw6q 1095 25 a a DT cord-006870-f5w6fw6q 1095 26 good good JJ cord-006870-f5w6fw6q 1095 27 outcome outcome NN cord-006870-f5w6fw6q 1095 28 . . . cord-006870-f5w6fw6q 1096 1 Timely timely JJ cord-006870-f5w6fw6q 1096 2 access access NN cord-006870-f5w6fw6q 1096 3 to to IN cord-006870-f5w6fw6q 1096 4 his -PRON- PRP$ cord-006870-f5w6fw6q 1096 5 past past JJ cord-006870-f5w6fw6q 1096 6 medical medical JJ cord-006870-f5w6fw6q 1096 7 history history NN cord-006870-f5w6fw6q 1096 8 and and CC cord-006870-f5w6fw6q 1096 9 medications medication NNS cord-006870-f5w6fw6q 1096 10 via via IN cord-006870-f5w6fw6q 1096 11 MEiD MEiD NNP cord-006870-f5w6fw6q 1096 12 was be VBD cord-006870-f5w6fw6q 1096 13 a a DT cord-006870-f5w6fw6q 1096 14 key key NN cord-006870-f5w6fw6q 1096 15 in in IN cord-006870-f5w6fw6q 1096 16 this this DT cord-006870-f5w6fw6q 1096 17 case case NN cord-006870-f5w6fw6q 1096 18 . . . cord-006870-f5w6fw6q 1097 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1097 2 cloud cloud NN cord-006870-f5w6fw6q 1097 3 based base VBD cord-006870-f5w6fw6q 1097 4 personal personal JJ cord-006870-f5w6fw6q 1097 5 healthcare healthcare NN cord-006870-f5w6fw6q 1097 6 information information NN cord-006870-f5w6fw6q 1097 7 platform platform NN cord-006870-f5w6fw6q 1097 8 using use VBG cord-006870-f5w6fw6q 1097 9 QR QR NNP cord-006870-f5w6fw6q 1097 10 codes code NNS cord-006870-f5w6fw6q 1097 11 from from IN cord-006870-f5w6fw6q 1097 12 wristbands wristband NNS cord-006870-f5w6fw6q 1097 13 and and CC cord-006870-f5w6fw6q 1097 14 stickers sticker NNS cord-006870-f5w6fw6q 1097 15 can can MD cord-006870-f5w6fw6q 1097 16 help help VB cord-006870-f5w6fw6q 1097 17 increase increase VB cord-006870-f5w6fw6q 1097 18 health health NN cord-006870-f5w6fw6q 1097 19 literacy literacy NN cord-006870-f5w6fw6q 1097 20 , , , cord-006870-f5w6fw6q 1097 21 decrease decrease VB cord-006870-f5w6fw6q 1097 22 times time NNS cord-006870-f5w6fw6q 1097 23 to to TO cord-006870-f5w6fw6q 1097 24 appropriate appropriate VB cord-006870-f5w6fw6q 1097 25 treatment treatment NN cord-006870-f5w6fw6q 1097 26 , , , cord-006870-f5w6fw6q 1097 27 improve improve VB cord-006870-f5w6fw6q 1097 28 patient patient JJ cord-006870-f5w6fw6q 1097 29 safety safety NN cord-006870-f5w6fw6q 1097 30 and and CC cord-006870-f5w6fw6q 1097 31 decrease decrease VB cord-006870-f5w6fw6q 1097 32 healthcare healthcare NN cord-006870-f5w6fw6q 1097 33 costs cost NNS cord-006870-f5w6fw6q 1097 34 . . . cord-006870-f5w6fw6q 1098 1 Clinical clinical JJ cord-006870-f5w6fw6q 1098 2 pharmacists pharmacist NNS cord-006870-f5w6fw6q 1098 3 have have VBP cord-006870-f5w6fw6q 1098 4 become become VBN cord-006870-f5w6fw6q 1098 5 an an DT cord-006870-f5w6fw6q 1098 6 integral integral JJ cord-006870-f5w6fw6q 1098 7 part part NN cord-006870-f5w6fw6q 1098 8 of of IN cord-006870-f5w6fw6q 1098 9 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 1098 10 medical medical JJ cord-006870-f5w6fw6q 1098 11 teams team NNS cord-006870-f5w6fw6q 1098 12 . . . cord-006870-f5w6fw6q 1099 1 Expanding expand VBG cord-006870-f5w6fw6q 1099 2 the the DT cord-006870-f5w6fw6q 1099 3 role role NN cord-006870-f5w6fw6q 1099 4 of of IN cord-006870-f5w6fw6q 1099 5 pharmacists pharmacist NNS cord-006870-f5w6fw6q 1099 6 in in IN cord-006870-f5w6fw6q 1099 7 the the DT cord-006870-f5w6fw6q 1099 8 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1099 9 care care NN cord-006870-f5w6fw6q 1099 10 units unit NNS cord-006870-f5w6fw6q 1099 11 has have VBZ cord-006870-f5w6fw6q 1099 12 the the DT cord-006870-f5w6fw6q 1099 13 potential potential NN cord-006870-f5w6fw6q 1099 14 to to TO cord-006870-f5w6fw6q 1099 15 positively positively RB cord-006870-f5w6fw6q 1099 16 impact impact VB cord-006870-f5w6fw6q 1099 17 the the DT cord-006870-f5w6fw6q 1099 18 quality quality NN cord-006870-f5w6fw6q 1099 19 of of IN cord-006870-f5w6fw6q 1099 20 patient patient JJ cord-006870-f5w6fw6q 1099 21 care care NN cord-006870-f5w6fw6q 1099 22 and and CC cord-006870-f5w6fw6q 1099 23 provide provide VB cord-006870-f5w6fw6q 1099 24 costs cost NNS cord-006870-f5w6fw6q 1099 25 savings saving NNS cord-006870-f5w6fw6q 1099 26 . . . cord-006870-f5w6fw6q 1100 1 This this DT cord-006870-f5w6fw6q 1100 2 study study NN cord-006870-f5w6fw6q 1100 3 examines examine VBZ cord-006870-f5w6fw6q 1100 4 these these DT cord-006870-f5w6fw6q 1100 5 potential potential JJ cord-006870-f5w6fw6q 1100 6 benefits benefit NNS cord-006870-f5w6fw6q 1100 7 at at IN cord-006870-f5w6fw6q 1100 8 one one CD cord-006870-f5w6fw6q 1100 9 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1100 10 care care NN cord-006870-f5w6fw6q 1100 11 unit unit NN cord-006870-f5w6fw6q 1100 12 . . . cord-006870-f5w6fw6q 1101 1 We -PRON- PRP cord-006870-f5w6fw6q 1101 2 reviewed review VBD cord-006870-f5w6fw6q 1101 3 patient patient JJ cord-006870-f5w6fw6q 1101 4 medication medication NN cord-006870-f5w6fw6q 1101 5 profiles profile NNS cord-006870-f5w6fw6q 1101 6 and and CC cord-006870-f5w6fw6q 1101 7 had have VBD cord-006870-f5w6fw6q 1101 8 formal formal JJ cord-006870-f5w6fw6q 1101 9 rounds round NNS cord-006870-f5w6fw6q 1101 10 with with IN cord-006870-f5w6fw6q 1101 11 a a DT cord-006870-f5w6fw6q 1101 12 pharmacist pharmacist NN cord-006870-f5w6fw6q 1101 13 four four CD cord-006870-f5w6fw6q 1101 14 times time NNS cord-006870-f5w6fw6q 1101 15 per per IN cord-006870-f5w6fw6q 1101 16 week week NN cord-006870-f5w6fw6q 1101 17 . . . cord-006870-f5w6fw6q 1102 1 For for IN cord-006870-f5w6fw6q 1102 2 the the DT cord-006870-f5w6fw6q 1102 3 purposes purpose NNS cord-006870-f5w6fw6q 1102 4 of of IN cord-006870-f5w6fw6q 1102 5 this this DT cord-006870-f5w6fw6q 1102 6 study study NN cord-006870-f5w6fw6q 1102 7 , , , cord-006870-f5w6fw6q 1102 8 the the DT cord-006870-f5w6fw6q 1102 9 focus focus NN cord-006870-f5w6fw6q 1102 10 was be VBD cord-006870-f5w6fw6q 1102 11 on on IN cord-006870-f5w6fw6q 1102 12 minimization minimization NN cord-006870-f5w6fw6q 1102 13 of of IN cord-006870-f5w6fw6q 1102 14 a a DT cord-006870-f5w6fw6q 1102 15 select select JJ cord-006870-f5w6fw6q 1102 16 number number NN cord-006870-f5w6fw6q 1102 17 of of IN cord-006870-f5w6fw6q 1102 18 high high JJ cord-006870-f5w6fw6q 1102 19 expense expense NN cord-006870-f5w6fw6q 1102 20 drugs drug NNS cord-006870-f5w6fw6q 1102 21 . . . cord-006870-f5w6fw6q 1103 1 Nine nine CD cord-006870-f5w6fw6q 1103 2 months month NNS cord-006870-f5w6fw6q 1103 3 of of IN cord-006870-f5w6fw6q 1103 4 baseline baseline JJ cord-006870-f5w6fw6q 1103 5 data datum NNS cord-006870-f5w6fw6q 1103 6 was be VBD cord-006870-f5w6fw6q 1103 7 compared compare VBN cord-006870-f5w6fw6q 1103 8 to to IN cord-006870-f5w6fw6q 1103 9 three three CD cord-006870-f5w6fw6q 1103 10 months month NNS cord-006870-f5w6fw6q 1103 11 of of IN cord-006870-f5w6fw6q 1103 12 post post NN cord-006870-f5w6fw6q 1103 13 intervention intervention NN cord-006870-f5w6fw6q 1103 14 data datum NNS cord-006870-f5w6fw6q 1103 15 . . . cord-006870-f5w6fw6q 1104 1 Interventions intervention NNS cord-006870-f5w6fw6q 1104 2 were be VBD cord-006870-f5w6fw6q 1104 3 performed perform VBN cord-006870-f5w6fw6q 1104 4 at at IN cord-006870-f5w6fw6q 1104 5 the the DT cord-006870-f5w6fw6q 1104 6 time time NN cord-006870-f5w6fw6q 1104 7 of of IN cord-006870-f5w6fw6q 1104 8 rounding rounding NN cord-006870-f5w6fw6q 1104 9 , , , cord-006870-f5w6fw6q 1104 10 which which WDT cord-006870-f5w6fw6q 1104 11 involved involve VBD cord-006870-f5w6fw6q 1104 12 timely timely JJ cord-006870-f5w6fw6q 1104 13 conversion conversion NN cord-006870-f5w6fw6q 1104 14 to to IN cord-006870-f5w6fw6q 1104 15 enteral enteral JJ cord-006870-f5w6fw6q 1104 16 formulas formula NNS cord-006870-f5w6fw6q 1104 17 , , , cord-006870-f5w6fw6q 1104 18 changes change NNS cord-006870-f5w6fw6q 1104 19 to to IN cord-006870-f5w6fw6q 1104 20 alternative alternative JJ cord-006870-f5w6fw6q 1104 21 medications medication NNS cord-006870-f5w6fw6q 1104 22 or or CC cord-006870-f5w6fw6q 1104 23 discontinuation discontinuation NN cord-006870-f5w6fw6q 1104 24 of of IN cord-006870-f5w6fw6q 1104 25 medications medication NNS cord-006870-f5w6fw6q 1104 26 . . . cord-006870-f5w6fw6q 1105 1 We -PRON- PRP cord-006870-f5w6fw6q 1105 2 then then RB cord-006870-f5w6fw6q 1105 3 performed perform VBD cord-006870-f5w6fw6q 1105 4 a a DT cord-006870-f5w6fw6q 1105 5 cost cost NN cord-006870-f5w6fw6q 1105 6 - - HYPH cord-006870-f5w6fw6q 1105 7 benefit benefit NN cord-006870-f5w6fw6q 1105 8 analysis analysis NN cord-006870-f5w6fw6q 1105 9 to to TO cord-006870-f5w6fw6q 1105 10 assess assess VB cord-006870-f5w6fw6q 1105 11 the the DT cord-006870-f5w6fw6q 1105 12 net net JJ cord-006870-f5w6fw6q 1105 13 amount amount NN cord-006870-f5w6fw6q 1105 14 of of IN cord-006870-f5w6fw6q 1105 15 money money NN cord-006870-f5w6fw6q 1105 16 saved save VBN cord-006870-f5w6fw6q 1105 17 by by IN cord-006870-f5w6fw6q 1105 18 reducing reduce VBG cord-006870-f5w6fw6q 1105 19 inappropriate inappropriate JJ cord-006870-f5w6fw6q 1105 20 pharmacy pharmacy NN cord-006870-f5w6fw6q 1105 21 drug drug NN cord-006870-f5w6fw6q 1105 22 use use NN cord-006870-f5w6fw6q 1105 23 following follow VBG cord-006870-f5w6fw6q 1105 24 the the DT cord-006870-f5w6fw6q 1105 25 interventions intervention NNS cord-006870-f5w6fw6q 1105 26 . . . cord-006870-f5w6fw6q 1106 1 Average average JJ cord-006870-f5w6fw6q 1106 2 cost cost NN cord-006870-f5w6fw6q 1106 3 of of IN cord-006870-f5w6fw6q 1106 4 nicardipine nicardipine NN cord-006870-f5w6fw6q 1106 5 was be VBD cord-006870-f5w6fw6q 1106 6 $ $ $ cord-006870-f5w6fw6q 1106 7 34,122 34,122 CD cord-006870-f5w6fw6q 1106 8 pre pre NN cord-006870-f5w6fw6q 1106 9 - - NN cord-006870-f5w6fw6q 1106 10 intervention intervention NN cord-006870-f5w6fw6q 1106 11 , , , cord-006870-f5w6fw6q 1106 12 compared compare VBN cord-006870-f5w6fw6q 1106 13 to to IN cord-006870-f5w6fw6q 1106 14 $ $ $ cord-006870-f5w6fw6q 1106 15 23 23 CD cord-006870-f5w6fw6q 1106 16 , , , cord-006870-f5w6fw6q 1106 17 871 871 CD cord-006870-f5w6fw6q 1106 18 post post NN cord-006870-f5w6fw6q 1106 19 - - NN cord-006870-f5w6fw6q 1106 20 intervention intervention JJ cord-006870-f5w6fw6q 1106 21 ( ( -LRB- cord-006870-f5w6fw6q 1106 22 pvalue pvalue NNP cord-006870-f5w6fw6q 1106 23 0.0229 0.0229 CD cord-006870-f5w6fw6q 1106 24 ) ) -RRB- cord-006870-f5w6fw6q 1106 25 . . . cord-006870-f5w6fw6q 1107 1 The the DT cord-006870-f5w6fw6q 1107 2 cost cost NN cord-006870-f5w6fw6q 1107 3 of of IN cord-006870-f5w6fw6q 1107 4 IV IV NNP cord-006870-f5w6fw6q 1107 5 levetiracetam levetiracetam VBZ cord-006870-f5w6fw6q 1107 6 usage usage NN cord-006870-f5w6fw6q 1107 7 on on IN cord-006870-f5w6fw6q 1107 8 average average JJ cord-006870-f5w6fw6q 1107 9 was be VBD cord-006870-f5w6fw6q 1107 10 $ $ $ cord-006870-f5w6fw6q 1107 11 4,719 4,719 CD cord-006870-f5w6fw6q 1107 12 pre pre JJ cord-006870-f5w6fw6q 1107 13 - - NN cord-006870-f5w6fw6q 1107 14 intervention intervention NN cord-006870-f5w6fw6q 1107 15 and and CC cord-006870-f5w6fw6q 1107 16 $ $ $ cord-006870-f5w6fw6q 1107 17 3,612 3,612 CD cord-006870-f5w6fw6q 1107 18 post post JJ cord-006870-f5w6fw6q 1107 19 - - NN cord-006870-f5w6fw6q 1107 20 intervention intervention JJ cord-006870-f5w6fw6q 1107 21 ( ( -LRB- cord-006870-f5w6fw6q 1107 22 p p NN cord-006870-f5w6fw6q 1107 23 - - HYPH cord-006870-f5w6fw6q 1107 24 value value NN cord-006870-f5w6fw6q 1107 25 0.102 0.102 CD cord-006870-f5w6fw6q 1107 26 ) ) -RRB- cord-006870-f5w6fw6q 1107 27 , , , cord-006870-f5w6fw6q 1107 28 while while IN cord-006870-f5w6fw6q 1107 29 the the DT cord-006870-f5w6fw6q 1107 30 cost cost NN cord-006870-f5w6fw6q 1107 31 of of IN cord-006870-f5w6fw6q 1107 32 IV IV NNP cord-006870-f5w6fw6q 1107 33 dexmedetomidine dexmedetomidine NNP cord-006870-f5w6fw6q 1107 34 was be VBD cord-006870-f5w6fw6q 1107 35 $ $ $ cord-006870-f5w6fw6q 1107 36 2355 2355 CD cord-006870-f5w6fw6q 1107 37 pre pre JJ cord-006870-f5w6fw6q 1107 38 - - NN cord-006870-f5w6fw6q 1107 39 intervention intervention NN cord-006870-f5w6fw6q 1107 40 compared compare VBN cord-006870-f5w6fw6q 1107 41 to to IN cord-006870-f5w6fw6q 1107 42 $ $ $ cord-006870-f5w6fw6q 1107 43 1800 1800 CD cord-006870-f5w6fw6q 1107 44 post post JJ cord-006870-f5w6fw6q 1107 45 - - NN cord-006870-f5w6fw6q 1107 46 intervention intervention JJ cord-006870-f5w6fw6q 1107 47 ( ( -LRB- cord-006870-f5w6fw6q 1107 48 p p NN cord-006870-f5w6fw6q 1107 49 - - HYPH cord-006870-f5w6fw6q 1107 50 value value NN cord-006870-f5w6fw6q 1107 51 0.5226 0.5226 CD cord-006870-f5w6fw6q 1107 52 ) ) -RRB- cord-006870-f5w6fw6q 1107 53 . . . cord-006870-f5w6fw6q 1108 1 Average average JJ cord-006870-f5w6fw6q 1108 2 expense expense NN cord-006870-f5w6fw6q 1108 3 per per IN cord-006870-f5w6fw6q 1108 4 month month NN cord-006870-f5w6fw6q 1108 5 was be VBD cord-006870-f5w6fw6q 1108 6 reduced reduce VBN cord-006870-f5w6fw6q 1108 7 by by IN cord-006870-f5w6fw6q 1108 8 approximately approximately RB cord-006870-f5w6fw6q 1108 9 $ $ $ cord-006870-f5w6fw6q 1108 10 11,900 11,900 CD cord-006870-f5w6fw6q 1108 11 per per IN cord-006870-f5w6fw6q 1108 12 month month NN cord-006870-f5w6fw6q 1108 13 compared compare VBN cord-006870-f5w6fw6q 1108 14 to to IN cord-006870-f5w6fw6q 1108 15 the the DT cord-006870-f5w6fw6q 1108 16 average average JJ cord-006870-f5w6fw6q 1108 17 expense expense NN cord-006870-f5w6fw6q 1108 18 per per IN cord-006870-f5w6fw6q 1108 19 month month NN cord-006870-f5w6fw6q 1108 20 from from IN cord-006870-f5w6fw6q 1108 21 the the DT cord-006870-f5w6fw6q 1108 22 previous previous JJ cord-006870-f5w6fw6q 1108 23 9 9 CD cord-006870-f5w6fw6q 1108 24 months month NNS cord-006870-f5w6fw6q 1108 25 ( ( -LRB- cord-006870-f5w6fw6q 1108 26 p p NN cord-006870-f5w6fw6q 1108 27 - - HYPH cord-006870-f5w6fw6q 1108 28 value value NN cord-006870-f5w6fw6q 1108 29 0.0128 0.0128 CD cord-006870-f5w6fw6q 1108 30 ) ) -RRB- cord-006870-f5w6fw6q 1108 31 . . . cord-006870-f5w6fw6q 1109 1 Appropriate appropriate JJ cord-006870-f5w6fw6q 1109 2 use use NN cord-006870-f5w6fw6q 1109 3 of of IN cord-006870-f5w6fw6q 1109 4 stress stress NN cord-006870-f5w6fw6q 1109 5 ulcer ulcer NN cord-006870-f5w6fw6q 1109 6 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 1109 7 was be VBD cord-006870-f5w6fw6q 1109 8 also also RB cord-006870-f5w6fw6q 1109 9 positively positively RB cord-006870-f5w6fw6q 1109 10 impacted impact VBN cord-006870-f5w6fw6q 1109 11 ; ; : cord-006870-f5w6fw6q 1109 12 patient patient JJ cord-006870-f5w6fw6q 1109 13 days day NNS cord-006870-f5w6fw6q 1109 14 / / SYM cord-006870-f5w6fw6q 1109 15 month month NN cord-006870-f5w6fw6q 1109 16 on on IN cord-006870-f5w6fw6q 1109 17 famotidine famotidine NNP cord-006870-f5w6fw6q 1109 18 was be VBD cord-006870-f5w6fw6q 1109 19 reduced reduce VBN cord-006870-f5w6fw6q 1109 20 by by IN cord-006870-f5w6fw6q 1109 21 approximately approximately RB cord-006870-f5w6fw6q 1109 22 30 30 CD cord-006870-f5w6fw6q 1109 23 % % NN cord-006870-f5w6fw6q 1109 24 from from IN cord-006870-f5w6fw6q 1109 25 baseline baseline NN cord-006870-f5w6fw6q 1109 26 , , , cord-006870-f5w6fw6q 1109 27 222 222 CD cord-006870-f5w6fw6q 1109 28 patient patient JJ cord-006870-f5w6fw6q 1109 29 days day NNS cord-006870-f5w6fw6q 1109 30 ( ( -LRB- cord-006870-f5w6fw6q 1109 31 pre pre JJ cord-006870-f5w6fw6q 1109 32 - - NN cord-006870-f5w6fw6q 1109 33 intervention intervention NN cord-006870-f5w6fw6q 1109 34 ) ) -RRB- cord-006870-f5w6fw6q 1109 35 vs vs IN cord-006870-f5w6fw6q 1109 36 150 150 CD cord-006870-f5w6fw6q 1109 37 days day NNS cord-006870-f5w6fw6q 1109 38 post post NN cord-006870-f5w6fw6q 1109 39 - - NN cord-006870-f5w6fw6q 1109 40 intervention intervention NN cord-006870-f5w6fw6q 1109 41 . . . cord-006870-f5w6fw6q 1110 1 Pharmacist pharmacist NN cord-006870-f5w6fw6q 1110 2 interventions intervention NNS cord-006870-f5w6fw6q 1110 3 within within IN cord-006870-f5w6fw6q 1110 4 a a DT cord-006870-f5w6fw6q 1110 5 neurocritical neurocritical JJ cord-006870-f5w6fw6q 1110 6 care care NN cord-006870-f5w6fw6q 1110 7 unit unit NN cord-006870-f5w6fw6q 1110 8 are be VBP cord-006870-f5w6fw6q 1110 9 known know VBN cord-006870-f5w6fw6q 1110 10 to to TO cord-006870-f5w6fw6q 1110 11 be be VB cord-006870-f5w6fw6q 1110 12 beneficial beneficial JJ cord-006870-f5w6fw6q 1110 13 clinically clinically RB cord-006870-f5w6fw6q 1110 14 for for IN cord-006870-f5w6fw6q 1110 15 patients patient NNS cord-006870-f5w6fw6q 1110 16 , , , cord-006870-f5w6fw6q 1110 17 however however RB cord-006870-f5w6fw6q 1110 18 this this DT cord-006870-f5w6fw6q 1110 19 study study NN cord-006870-f5w6fw6q 1110 20 also also RB cord-006870-f5w6fw6q 1110 21 shows show VBZ cord-006870-f5w6fw6q 1110 22 that that IN cord-006870-f5w6fw6q 1110 23 their -PRON- PRP$ cord-006870-f5w6fw6q 1110 24 interventions intervention NNS cord-006870-f5w6fw6q 1110 25 offer offer VBP cord-006870-f5w6fw6q 1110 26 substantial substantial JJ cord-006870-f5w6fw6q 1110 27 cost cost NN cord-006870-f5w6fw6q 1110 28 benefits benefit NNS cord-006870-f5w6fw6q 1110 29 and and CC cord-006870-f5w6fw6q 1110 30 should should MD cord-006870-f5w6fw6q 1110 31 justify justify VB cord-006870-f5w6fw6q 1110 32 creating create VBG cord-006870-f5w6fw6q 1110 33 collaborations collaboration NNS cord-006870-f5w6fw6q 1110 34 between between IN cord-006870-f5w6fw6q 1110 35 pharmacists pharmacist NNS cord-006870-f5w6fw6q 1110 36 and and CC cord-006870-f5w6fw6q 1110 37 neurointensivists neurointensivist NNS cord-006870-f5w6fw6q 1110 38 . . . cord-006870-f5w6fw6q 1111 1 Multi multi JJ cord-006870-f5w6fw6q 1111 2 - - JJ cord-006870-f5w6fw6q 1111 3 disciplinary disciplinary JJ cord-006870-f5w6fw6q 1111 4 rounds round NNS cord-006870-f5w6fw6q 1111 5 have have VBP cord-006870-f5w6fw6q 1111 6 been be VBN cord-006870-f5w6fw6q 1111 7 shown show VBN cord-006870-f5w6fw6q 1111 8 to to TO cord-006870-f5w6fw6q 1111 9 improve improve VB cord-006870-f5w6fw6q 1111 10 patient patient JJ cord-006870-f5w6fw6q 1111 11 outcomes outcome NNS cord-006870-f5w6fw6q 1111 12 . . . cord-006870-f5w6fw6q 1112 1 The the DT cord-006870-f5w6fw6q 1112 2 objective objective NN cord-006870-f5w6fw6q 1112 3 of of IN cord-006870-f5w6fw6q 1112 4 this this DT cord-006870-f5w6fw6q 1112 5 study study NN cord-006870-f5w6fw6q 1112 6 is be VBZ cord-006870-f5w6fw6q 1112 7 to to TO cord-006870-f5w6fw6q 1112 8 observe observe VB cord-006870-f5w6fw6q 1112 9 the the DT cord-006870-f5w6fw6q 1112 10 effect effect NN cord-006870-f5w6fw6q 1112 11 on on IN cord-006870-f5w6fw6q 1112 12 patient patient JJ cord-006870-f5w6fw6q 1112 13 care care NN cord-006870-f5w6fw6q 1112 14 , , , cord-006870-f5w6fw6q 1112 15 team team NN cord-006870-f5w6fw6q 1112 16 dynamic dynamic JJ cord-006870-f5w6fw6q 1112 17 , , , cord-006870-f5w6fw6q 1112 18 and and CC cord-006870-f5w6fw6q 1112 19 nursing nursing NN cord-006870-f5w6fw6q 1112 20 satisfaction satisfaction NN cord-006870-f5w6fw6q 1112 21 before before IN cord-006870-f5w6fw6q 1112 22 and and CC cord-006870-f5w6fw6q 1112 23 after after IN cord-006870-f5w6fw6q 1112 24 the the DT cord-006870-f5w6fw6q 1112 25 implementation implementation NN cord-006870-f5w6fw6q 1112 26 of of IN cord-006870-f5w6fw6q 1112 27 a a DT cord-006870-f5w6fw6q 1112 28 nursing nursing NN cord-006870-f5w6fw6q 1112 29 - - HYPH cord-006870-f5w6fw6q 1112 30 led lead VBN cord-006870-f5w6fw6q 1112 31 rounding rounding NN cord-006870-f5w6fw6q 1112 32 model model NN cord-006870-f5w6fw6q 1112 33 in in IN cord-006870-f5w6fw6q 1112 34 the the DT cord-006870-f5w6fw6q 1112 35 Neurological Neurological NNP cord-006870-f5w6fw6q 1112 36 ICU ICU NNP cord-006870-f5w6fw6q 1112 37 . . . cord-006870-f5w6fw6q 1113 1 Prior prior RB cord-006870-f5w6fw6q 1113 2 to to IN cord-006870-f5w6fw6q 1113 3 the the DT cord-006870-f5w6fw6q 1113 4 implementation implementation NN cord-006870-f5w6fw6q 1113 5 of of IN cord-006870-f5w6fw6q 1113 6 the the DT cord-006870-f5w6fw6q 1113 7 nursing nursing NN cord-006870-f5w6fw6q 1113 8 - - HYPH cord-006870-f5w6fw6q 1113 9 led lead VBN cord-006870-f5w6fw6q 1113 10 rounds round NNS cord-006870-f5w6fw6q 1113 11 quality quality NN cord-006870-f5w6fw6q 1113 12 initiative initiative NN cord-006870-f5w6fw6q 1113 13 , , , cord-006870-f5w6fw6q 1113 14 nurses nurse NNS cord-006870-f5w6fw6q 1113 15 in in IN cord-006870-f5w6fw6q 1113 16 the the DT cord-006870-f5w6fw6q 1113 17 neurointensive neurointensive NNP cord-006870-f5w6fw6q 1113 18 care care NN cord-006870-f5w6fw6q 1113 19 unit unit NN cord-006870-f5w6fw6q 1113 20 ( ( -LRB- cord-006870-f5w6fw6q 1113 21 NICU NICU NNP cord-006870-f5w6fw6q 1113 22 ) ) -RRB- cord-006870-f5w6fw6q 1113 23 were be VBD cord-006870-f5w6fw6q 1113 24 asked ask VBN cord-006870-f5w6fw6q 1113 25 to to TO cord-006870-f5w6fw6q 1113 26 answer answer VB cord-006870-f5w6fw6q 1113 27 a a DT cord-006870-f5w6fw6q 1113 28 brief brief JJ cord-006870-f5w6fw6q 1113 29 survey survey NN cord-006870-f5w6fw6q 1113 30 on on IN cord-006870-f5w6fw6q 1113 31 basic basic JJ cord-006870-f5w6fw6q 1113 32 demographics demographic NNS cord-006870-f5w6fw6q 1113 33 and and CC cord-006870-f5w6fw6q 1113 34 perceptions perception NNS cord-006870-f5w6fw6q 1113 35 of of IN cord-006870-f5w6fw6q 1113 36 team team NN cord-006870-f5w6fw6q 1113 37 dynamics dynamic NNS cord-006870-f5w6fw6q 1113 38 and and CC cord-006870-f5w6fw6q 1113 39 satisfaction satisfaction NN cord-006870-f5w6fw6q 1113 40 in in IN cord-006870-f5w6fw6q 1113 41 the the DT cord-006870-f5w6fw6q 1113 42 NICU NICU NNP cord-006870-f5w6fw6q 1113 43 . . . cord-006870-f5w6fw6q 1114 1 A a DT cord-006870-f5w6fw6q 1114 2 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 1114 3 systems system NNS cord-006870-f5w6fw6q 1114 4 - - HYPH cord-006870-f5w6fw6q 1114 5 based base VBN cord-006870-f5w6fw6q 1114 6 rounding rounding NN cord-006870-f5w6fw6q 1114 7 sheet sheet NN cord-006870-f5w6fw6q 1114 8 inclusive inclusive JJ cord-006870-f5w6fw6q 1114 9 of of IN cord-006870-f5w6fw6q 1114 10 the the DT cord-006870-f5w6fw6q 1114 11 ABCDEF ABCDEF NNP cord-006870-f5w6fw6q 1114 12 bundle bundle NN cord-006870-f5w6fw6q 1114 13 and and CC cord-006870-f5w6fw6q 1114 14 previous previous JJ cord-006870-f5w6fw6q 1114 15 NICU NICU NNP cord-006870-f5w6fw6q 1114 16 checklist checklist NN cord-006870-f5w6fw6q 1114 17 was be VBD cord-006870-f5w6fw6q 1114 18 created create VBN cord-006870-f5w6fw6q 1114 19 and and CC cord-006870-f5w6fw6q 1114 20 revised revise VBN cord-006870-f5w6fw6q 1114 21 with with IN cord-006870-f5w6fw6q 1114 22 extensive extensive JJ cord-006870-f5w6fw6q 1114 23 bedside bedside NN cord-006870-f5w6fw6q 1114 24 and and CC cord-006870-f5w6fw6q 1114 25 senior senior JJ cord-006870-f5w6fw6q 1114 26 nursing nursing NN cord-006870-f5w6fw6q 1114 27 educator educator NN cord-006870-f5w6fw6q 1114 28 input input NN cord-006870-f5w6fw6q 1114 29 . . . cord-006870-f5w6fw6q 1115 1 While while IN cord-006870-f5w6fw6q 1115 2 rounding round VBG cord-006870-f5w6fw6q 1115 3 , , , cord-006870-f5w6fw6q 1115 4 nurses nurse NNS cord-006870-f5w6fw6q 1115 5 presented present VBN cord-006870-f5w6fw6q 1115 6 and and CC cord-006870-f5w6fw6q 1115 7 clinicians clinician NNS cord-006870-f5w6fw6q 1115 8 were be VBD cord-006870-f5w6fw6q 1115 9 to to TO cord-006870-f5w6fw6q 1115 10 in in IN cord-006870-f5w6fw6q 1115 11 real real JJ cord-006870-f5w6fw6q 1115 12 - - HYPH cord-006870-f5w6fw6q 1115 13 time time NN cord-006870-f5w6fw6q 1115 14 come come VB cord-006870-f5w6fw6q 1115 15 up up RP cord-006870-f5w6fw6q 1115 16 with with IN cord-006870-f5w6fw6q 1115 17 an an DT cord-006870-f5w6fw6q 1115 18 assessment assessment NN cord-006870-f5w6fw6q 1115 19 and and CC cord-006870-f5w6fw6q 1115 20 plan plan NN cord-006870-f5w6fw6q 1115 21 and and CC cord-006870-f5w6fw6q 1115 22 relay relay VB cord-006870-f5w6fw6q 1115 23 these these DT cord-006870-f5w6fw6q 1115 24 to to IN cord-006870-f5w6fw6q 1115 25 the the DT cord-006870-f5w6fw6q 1115 26 nurse nurse NN cord-006870-f5w6fw6q 1115 27 and and CC cord-006870-f5w6fw6q 1115 28 other other JJ cord-006870-f5w6fw6q 1115 29 team team NN cord-006870-f5w6fw6q 1115 30 members member NNS cord-006870-f5w6fw6q 1115 31 . . . cord-006870-f5w6fw6q 1116 1 Any any DT cord-006870-f5w6fw6q 1116 2 questions question NNS cord-006870-f5w6fw6q 1116 3 , , , cord-006870-f5w6fw6q 1116 4 educational educational JJ cord-006870-f5w6fw6q 1116 5 pearls pearl NNS cord-006870-f5w6fw6q 1116 6 or or CC cord-006870-f5w6fw6q 1116 7 concerns concern NNS cord-006870-f5w6fw6q 1116 8 by by IN cord-006870-f5w6fw6q 1116 9 the the DT cord-006870-f5w6fw6q 1116 10 clinician clinician JJ cord-006870-f5w6fw6q 1116 11 team team NN cord-006870-f5w6fw6q 1116 12 or or CC cord-006870-f5w6fw6q 1116 13 the the DT cord-006870-f5w6fw6q 1116 14 bedside bedside NN cord-006870-f5w6fw6q 1116 15 nurse nurse NN cord-006870-f5w6fw6q 1116 16 were be VBD cord-006870-f5w6fw6q 1116 17 encouraged encourage VBN cord-006870-f5w6fw6q 1116 18 during during IN cord-006870-f5w6fw6q 1116 19 these these DT cord-006870-f5w6fw6q 1116 20 rounds round NNS cord-006870-f5w6fw6q 1116 21 . . . cord-006870-f5w6fw6q 1117 1 Nurses nurse NNS cord-006870-f5w6fw6q 1117 2 completed complete VBD cord-006870-f5w6fw6q 1117 3 a a DT cord-006870-f5w6fw6q 1117 4 6 6 CD cord-006870-f5w6fw6q 1117 5 month month NN cord-006870-f5w6fw6q 1117 6 post post NN cord-006870-f5w6fw6q 1117 7 - - NN cord-006870-f5w6fw6q 1117 8 implementation implementation JJ cord-006870-f5w6fw6q 1117 9 survey survey NN cord-006870-f5w6fw6q 1117 10 . . . cord-006870-f5w6fw6q 1118 1 42 42 CD cord-006870-f5w6fw6q 1118 2 of of IN cord-006870-f5w6fw6q 1118 3 the the DT cord-006870-f5w6fw6q 1118 4 full full JJ cord-006870-f5w6fw6q 1118 5 - - HYPH cord-006870-f5w6fw6q 1118 6 time time NN cord-006870-f5w6fw6q 1118 7 NICU NICU NNP cord-006870-f5w6fw6q 1118 8 nurses nurse NNS cord-006870-f5w6fw6q 1118 9 ( ( -LRB- cord-006870-f5w6fw6q 1118 10 71 71 CD cord-006870-f5w6fw6q 1118 11 % % NN cord-006870-f5w6fw6q 1118 12 ) ) -RRB- cord-006870-f5w6fw6q 1118 13 responded respond VBD cord-006870-f5w6fw6q 1118 14 to to IN cord-006870-f5w6fw6q 1118 15 both both CC cord-006870-f5w6fw6q 1118 16 the the DT cord-006870-f5w6fw6q 1118 17 pre pre NN cord-006870-f5w6fw6q 1118 18 - - NN cord-006870-f5w6fw6q 1118 19 implementation implementation NN cord-006870-f5w6fw6q 1118 20 and and CC cord-006870-f5w6fw6q 1118 21 postimplementation postimplementation NN cord-006870-f5w6fw6q 1118 22 surveys survey NNS cord-006870-f5w6fw6q 1118 23 . . . cord-006870-f5w6fw6q 1119 1 A a DT cord-006870-f5w6fw6q 1119 2 bimodal bimodal JJ cord-006870-f5w6fw6q 1119 3 distribution distribution NN cord-006870-f5w6fw6q 1119 4 of of IN cord-006870-f5w6fw6q 1119 5 nursing nursing NN cord-006870-f5w6fw6q 1119 6 experience experience NN cord-006870-f5w6fw6q 1119 7 was be VBD cord-006870-f5w6fw6q 1119 8 noted note VBN cord-006870-f5w6fw6q 1119 9 with with IN cord-006870-f5w6fw6q 1119 10 41 41 CD cord-006870-f5w6fw6q 1119 11 % % NN cord-006870-f5w6fw6q 1119 12 new new JJ cord-006870-f5w6fw6q 1119 13 nurses nurse NNS cord-006870-f5w6fw6q 1119 14 ( ( -LRB- cord-006870-f5w6fw6q 1119 15 < < NNP cord-006870-f5w6fw6q 1119 16 1 1 CD cord-006870-f5w6fw6q 1119 17 year year NN cord-006870-f5w6fw6q 1119 18 ) ) -RRB- cord-006870-f5w6fw6q 1119 19 and and CC cord-006870-f5w6fw6q 1119 20 31 31 CD cord-006870-f5w6fw6q 1119 21 % % NN cord-006870-f5w6fw6q 1119 22 experienced experienced JJ cord-006870-f5w6fw6q 1119 23 nurses nurse NNS cord-006870-f5w6fw6q 1119 24 ( ( -LRB- cord-006870-f5w6fw6q 1119 25 5 5 CD cord-006870-f5w6fw6q 1119 26 years+ years+ NN cord-006870-f5w6fw6q 1119 27 ) ) -RRB- cord-006870-f5w6fw6q 1119 28 . . . cord-006870-f5w6fw6q 1120 1 More More JJR cord-006870-f5w6fw6q 1120 2 than than IN cord-006870-f5w6fw6q 1120 3 half half NN cord-006870-f5w6fw6q 1120 4 of of IN cord-006870-f5w6fw6q 1120 5 the the DT cord-006870-f5w6fw6q 1120 6 nurses nurse NNS cord-006870-f5w6fw6q 1120 7 ( ( -LRB- cord-006870-f5w6fw6q 1120 8 68 68 CD cord-006870-f5w6fw6q 1120 9 % % NN cord-006870-f5w6fw6q 1120 10 ) ) -RRB- cord-006870-f5w6fw6q 1120 11 reported report VBD cord-006870-f5w6fw6q 1120 12 doing do VBG cord-006870-f5w6fw6q 1120 13 both both CC cord-006870-f5w6fw6q 1120 14 night night NN cord-006870-f5w6fw6q 1120 15 and and CC cord-006870-f5w6fw6q 1120 16 day day NN cord-006870-f5w6fw6q 1120 17 shifts shift NNS cord-006870-f5w6fw6q 1120 18 as as IN cord-006870-f5w6fw6q 1120 19 opposed oppose VBN cord-006870-f5w6fw6q 1120 20 to to IN cord-006870-f5w6fw6q 1120 21 being be VBG cord-006870-f5w6fw6q 1120 22 exclusive exclusive JJ cord-006870-f5w6fw6q 1120 23 to to IN cord-006870-f5w6fw6q 1120 24 only only JJ cord-006870-f5w6fw6q 1120 25 day day NN cord-006870-f5w6fw6q 1120 26 or or CC cord-006870-f5w6fw6q 1120 27 night night NN cord-006870-f5w6fw6q 1120 28 . . . cord-006870-f5w6fw6q 1121 1 There there EX cord-006870-f5w6fw6q 1121 2 was be VBD cord-006870-f5w6fw6q 1121 3 an an DT cord-006870-f5w6fw6q 1121 4 increase increase NN cord-006870-f5w6fw6q 1121 5 in in IN cord-006870-f5w6fw6q 1121 6 the the DT cord-006870-f5w6fw6q 1121 7 nursing nursing NN cord-006870-f5w6fw6q 1121 8 perceptions perception NNS cord-006870-f5w6fw6q 1121 9 of of IN cord-006870-f5w6fw6q 1121 10 participation participation NN cord-006870-f5w6fw6q 1121 11 during during IN cord-006870-f5w6fw6q 1121 12 rounds round NNS cord-006870-f5w6fw6q 1121 13 as as RB cord-006870-f5w6fw6q 1121 14 well well RB cord-006870-f5w6fw6q 1121 15 as as IN cord-006870-f5w6fw6q 1121 16 education education NN cord-006870-f5w6fw6q 1121 17 during during IN cord-006870-f5w6fw6q 1121 18 rounds round NNS cord-006870-f5w6fw6q 1121 19 . . . cord-006870-f5w6fw6q 1122 1 Nurses nurse NNS cord-006870-f5w6fw6q 1122 2 felt feel VBD cord-006870-f5w6fw6q 1122 3 significantly significantly RB cord-006870-f5w6fw6q 1122 4 more more RBR cord-006870-f5w6fw6q 1122 5 involved involved JJ cord-006870-f5w6fw6q 1122 6 with with IN cord-006870-f5w6fw6q 1122 7 patient patient JJ cord-006870-f5w6fw6q 1122 8 decision decision NN cord-006870-f5w6fw6q 1122 9 making making NN cord-006870-f5w6fw6q 1122 10 and and CC cord-006870-f5w6fw6q 1122 11 felt feel VBD cord-006870-f5w6fw6q 1122 12 that that IN cord-006870-f5w6fw6q 1122 13 they -PRON- PRP cord-006870-f5w6fw6q 1122 14 were be VBD cord-006870-f5w6fw6q 1122 15 able able JJ cord-006870-f5w6fw6q 1122 16 to to TO cord-006870-f5w6fw6q 1122 17 give give VB cord-006870-f5w6fw6q 1122 18 input input NN cord-006870-f5w6fw6q 1122 19 into into IN cord-006870-f5w6fw6q 1122 20 the the DT cord-006870-f5w6fw6q 1122 21 patients patient NNS cord-006870-f5w6fw6q 1122 22 care care VBP cord-006870-f5w6fw6q 1122 23 . . . cord-006870-f5w6fw6q 1123 1 The the DT cord-006870-f5w6fw6q 1123 2 implementation implementation NN cord-006870-f5w6fw6q 1123 3 of of IN cord-006870-f5w6fw6q 1123 4 a a DT cord-006870-f5w6fw6q 1123 5 nursing nursing NN cord-006870-f5w6fw6q 1123 6 - - HYPH cord-006870-f5w6fw6q 1123 7 led lead VBN cord-006870-f5w6fw6q 1123 8 rounding round VBG cord-006870-f5w6fw6q 1123 9 structure structure NN cord-006870-f5w6fw6q 1123 10 may may MD cord-006870-f5w6fw6q 1123 11 be be VB cord-006870-f5w6fw6q 1123 12 beneficial beneficial JJ cord-006870-f5w6fw6q 1123 13 to to IN cord-006870-f5w6fw6q 1123 14 communication communication NN cord-006870-f5w6fw6q 1123 15 , , , cord-006870-f5w6fw6q 1123 16 education education NN cord-006870-f5w6fw6q 1123 17 and and CC cord-006870-f5w6fw6q 1123 18 overall overall JJ cord-006870-f5w6fw6q 1123 19 patient patient JJ cord-006870-f5w6fw6q 1123 20 care care NN cord-006870-f5w6fw6q 1123 21 . . . cord-006870-f5w6fw6q 1124 1 As as IN cord-006870-f5w6fw6q 1124 2 the the DT cord-006870-f5w6fw6q 1124 3 project project NN cord-006870-f5w6fw6q 1124 4 continues continue VBZ cord-006870-f5w6fw6q 1124 5 , , , cord-006870-f5w6fw6q 1124 6 we -PRON- PRP cord-006870-f5w6fw6q 1124 7 hope hope VBP cord-006870-f5w6fw6q 1124 8 to to TO cord-006870-f5w6fw6q 1124 9 further further RB cord-006870-f5w6fw6q 1124 10 examine examine VB cord-006870-f5w6fw6q 1124 11 common common JJ cord-006870-f5w6fw6q 1124 12 ICU ICU NNP cord-006870-f5w6fw6q 1124 13 objective objective JJ cord-006870-f5w6fw6q 1124 14 measures measure NNS cord-006870-f5w6fw6q 1124 15 as as RB cord-006870-f5w6fw6q 1124 16 well well RB cord-006870-f5w6fw6q 1124 17 as as IN cord-006870-f5w6fw6q 1124 18 other other JJ cord-006870-f5w6fw6q 1124 19 subjective subjective JJ cord-006870-f5w6fw6q 1124 20 measures measure NNS cord-006870-f5w6fw6q 1124 21 such such JJ cord-006870-f5w6fw6q 1124 22 as as IN cord-006870-f5w6fw6q 1124 23 patient patient JJ cord-006870-f5w6fw6q 1124 24 satisfaction satisfaction NN cord-006870-f5w6fw6q 1124 25 scores score NNS cord-006870-f5w6fw6q 1124 26 and and CC cord-006870-f5w6fw6q 1124 27 communication communication NN cord-006870-f5w6fw6q 1124 28 perceptions perception NNS cord-006870-f5w6fw6q 1124 29 . . . cord-006870-f5w6fw6q 1125 1 With with IN cord-006870-f5w6fw6q 1125 2 increased increase VBN cord-006870-f5w6fw6q 1125 3 elective elective JJ cord-006870-f5w6fw6q 1125 4 and and CC cord-006870-f5w6fw6q 1125 5 non non JJ cord-006870-f5w6fw6q 1125 6 - - JJ cord-006870-f5w6fw6q 1125 7 elective elective JJ cord-006870-f5w6fw6q 1125 8 volume volume NN cord-006870-f5w6fw6q 1125 9 , , , cord-006870-f5w6fw6q 1125 10 directing direct VBG cord-006870-f5w6fw6q 1125 11 the the DT cord-006870-f5w6fw6q 1125 12 flow flow NN cord-006870-f5w6fw6q 1125 13 of of IN cord-006870-f5w6fw6q 1125 14 admissions admission NNS cord-006870-f5w6fw6q 1125 15 has have VBZ cord-006870-f5w6fw6q 1125 16 become become VBN cord-006870-f5w6fw6q 1125 17 essential essential JJ cord-006870-f5w6fw6q 1125 18 to to IN cord-006870-f5w6fw6q 1125 19 the the DT cord-006870-f5w6fw6q 1125 20 efficient efficient JJ cord-006870-f5w6fw6q 1125 21 operation operation NN cord-006870-f5w6fw6q 1125 22 of of IN cord-006870-f5w6fw6q 1125 23 inpatient inpatient JJ cord-006870-f5w6fw6q 1125 24 strategic strategic JJ cord-006870-f5w6fw6q 1125 25 service service NN cord-006870-f5w6fw6q 1125 26 lines line NNS cord-006870-f5w6fw6q 1125 27 . . . cord-006870-f5w6fw6q 1126 1 This this DT cord-006870-f5w6fw6q 1126 2 is be VBZ cord-006870-f5w6fw6q 1126 3 especially especially RB cord-006870-f5w6fw6q 1126 4 true true JJ cord-006870-f5w6fw6q 1126 5 in in IN cord-006870-f5w6fw6q 1126 6 the the DT cord-006870-f5w6fw6q 1126 7 Neurosciences Neurosciences NNPS cord-006870-f5w6fw6q 1126 8 where where WRB cord-006870-f5w6fw6q 1126 9 widespread widespread JJ cord-006870-f5w6fw6q 1126 10 acute acute JJ cord-006870-f5w6fw6q 1126 11 ischemic ischemic JJ cord-006870-f5w6fw6q 1126 12 stroke stroke NN cord-006870-f5w6fw6q 1126 13 intervention intervention NN cord-006870-f5w6fw6q 1126 14 has have VBZ cord-006870-f5w6fw6q 1126 15 placed place VBN cord-006870-f5w6fw6q 1126 16 an an DT cord-006870-f5w6fw6q 1126 17 especially especially RB cord-006870-f5w6fw6q 1126 18 high high JJ cord-006870-f5w6fw6q 1126 19 demand demand NN cord-006870-f5w6fw6q 1126 20 on on IN cord-006870-f5w6fw6q 1126 21 Comprehensive Comprehensive NNP cord-006870-f5w6fw6q 1126 22 Stroke Stroke NNP cord-006870-f5w6fw6q 1126 23 Centers Centers NNPS cord-006870-f5w6fw6q 1126 24 . . . cord-006870-f5w6fw6q 1127 1 As as IN cord-006870-f5w6fw6q 1127 2 a a DT cord-006870-f5w6fw6q 1127 3 result result NN cord-006870-f5w6fw6q 1127 4 , , , cord-006870-f5w6fw6q 1127 5 an an DT cord-006870-f5w6fw6q 1127 6 important important JJ cord-006870-f5w6fw6q 1127 7 collaboration collaboration NN cord-006870-f5w6fw6q 1127 8 was be VBD cord-006870-f5w6fw6q 1127 9 formed form VBN cord-006870-f5w6fw6q 1127 10 at at IN cord-006870-f5w6fw6q 1127 11 Duke Duke NNP cord-006870-f5w6fw6q 1127 12 between between IN cord-006870-f5w6fw6q 1127 13 the the DT cord-006870-f5w6fw6q 1127 14 Health Health NNP cord-006870-f5w6fw6q 1127 15 System System NNP cord-006870-f5w6fw6q 1127 16 , , , cord-006870-f5w6fw6q 1127 17 Transfer Transfer NNP cord-006870-f5w6fw6q 1127 18 Center Center NNP cord-006870-f5w6fw6q 1127 19 and and CC cord-006870-f5w6fw6q 1127 20 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 1127 21 to to TO cord-006870-f5w6fw6q 1127 22 create create VB cord-006870-f5w6fw6q 1127 23 an an DT cord-006870-f5w6fw6q 1127 24 algorithm algorithm NN cord-006870-f5w6fw6q 1127 25 - - HYPH cord-006870-f5w6fw6q 1127 26 driven drive VBN cord-006870-f5w6fw6q 1127 27 multi multi JJ cord-006870-f5w6fw6q 1127 28 - - JJ cord-006870-f5w6fw6q 1127 29 hospital hospital JJ cord-006870-f5w6fw6q 1127 30 triage triage NN cord-006870-f5w6fw6q 1127 31 and and CC cord-006870-f5w6fw6q 1127 32 pre pre JJ cord-006870-f5w6fw6q 1127 33 - - JJ cord-006870-f5w6fw6q 1127 34 hospital hospital JJ cord-006870-f5w6fw6q 1127 35 care care NN cord-006870-f5w6fw6q 1127 36 system system NN cord-006870-f5w6fw6q 1127 37 called call VBN cord-006870-f5w6fw6q 1127 38 PHAST PHAST NNP cord-006870-f5w6fw6q 1127 39 ( ( -LRB- cord-006870-f5w6fw6q 1127 40 Pre Pre NNP cord-006870-f5w6fw6q 1127 41 - - NNP cord-006870-f5w6fw6q 1127 42 Hospital Hospital NNP cord-006870-f5w6fw6q 1127 43 Acute Acute NNP cord-006870-f5w6fw6q 1127 44 Services Services NNPS cord-006870-f5w6fw6q 1127 45 Team Team NNP cord-006870-f5w6fw6q 1127 46 ) ) -RRB- cord-006870-f5w6fw6q 1127 47 . . . cord-006870-f5w6fw6q 1128 1 In in IN cord-006870-f5w6fw6q 1128 2 this this DT cord-006870-f5w6fw6q 1128 3 abstract abstract NN cord-006870-f5w6fw6q 1128 4 , , , cord-006870-f5w6fw6q 1128 5 we -PRON- PRP cord-006870-f5w6fw6q 1128 6 present present VBP cord-006870-f5w6fw6q 1128 7 the the DT cord-006870-f5w6fw6q 1128 8 formation formation NN cord-006870-f5w6fw6q 1128 9 and and CC cord-006870-f5w6fw6q 1128 10 current current JJ cord-006870-f5w6fw6q 1128 11 state state NN cord-006870-f5w6fw6q 1128 12 of of IN cord-006870-f5w6fw6q 1128 13 this this DT cord-006870-f5w6fw6q 1128 14 service service NN cord-006870-f5w6fw6q 1128 15 . . . cord-006870-f5w6fw6q 1129 1 This this DT cord-006870-f5w6fw6q 1129 2 effort effort NN cord-006870-f5w6fw6q 1129 3 was be VBD cord-006870-f5w6fw6q 1129 4 formally formally RB cord-006870-f5w6fw6q 1129 5 begun begin VBN cord-006870-f5w6fw6q 1129 6 in in IN cord-006870-f5w6fw6q 1129 7 the the DT cord-006870-f5w6fw6q 1129 8 Spring Spring NNP cord-006870-f5w6fw6q 1129 9 of of IN cord-006870-f5w6fw6q 1129 10 2015 2015 CD cord-006870-f5w6fw6q 1129 11 with with IN cord-006870-f5w6fw6q 1129 12 an an DT cord-006870-f5w6fw6q 1129 13 initial initial JJ cord-006870-f5w6fw6q 1129 14 focus focus NN cord-006870-f5w6fw6q 1129 15 on on IN cord-006870-f5w6fw6q 1129 16 centralizing centralize VBG cord-006870-f5w6fw6q 1129 17 the the DT cord-006870-f5w6fw6q 1129 18 admission admission NN cord-006870-f5w6fw6q 1129 19 process process NN cord-006870-f5w6fw6q 1129 20 into into IN cord-006870-f5w6fw6q 1129 21 the the DT cord-006870-f5w6fw6q 1129 22 Duke Duke NNP cord-006870-f5w6fw6q 1129 23 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 1129 24 Intensive Intensive NNP cord-006870-f5w6fw6q 1129 25 Care Care NNP cord-006870-f5w6fw6q 1129 26 Unit Unit NNP cord-006870-f5w6fw6q 1129 27 ( ( -LRB- cord-006870-f5w6fw6q 1129 28 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 1129 29 ) ) -RRB- cord-006870-f5w6fw6q 1129 30 by by IN cord-006870-f5w6fw6q 1129 31 an an DT cord-006870-f5w6fw6q 1129 32 ICU ICU NNP cord-006870-f5w6fw6q 1129 33 physician physician NN cord-006870-f5w6fw6q 1129 34 . . . cord-006870-f5w6fw6q 1130 1 After after IN cord-006870-f5w6fw6q 1130 2 some some DT cord-006870-f5w6fw6q 1130 3 initial initial JJ cord-006870-f5w6fw6q 1130 4 success success NN cord-006870-f5w6fw6q 1130 5 , , , cord-006870-f5w6fw6q 1130 6 it -PRON- PRP cord-006870-f5w6fw6q 1130 7 was be VBD cord-006870-f5w6fw6q 1130 8 clear clear JJ cord-006870-f5w6fw6q 1130 9 that that IN cord-006870-f5w6fw6q 1130 10 the the DT cord-006870-f5w6fw6q 1130 11 service service NN cord-006870-f5w6fw6q 1130 12 line line NN cord-006870-f5w6fw6q 1130 13 would would MD cord-006870-f5w6fw6q 1130 14 benefit benefit VB cord-006870-f5w6fw6q 1130 15 from from IN cord-006870-f5w6fw6q 1130 16 a a DT cord-006870-f5w6fw6q 1130 17 more more RBR cord-006870-f5w6fw6q 1130 18 formalized formalized JJ cord-006870-f5w6fw6q 1130 19 process process NN cord-006870-f5w6fw6q 1130 20 . . . cord-006870-f5w6fw6q 1131 1 As as IN cord-006870-f5w6fw6q 1131 2 a a DT cord-006870-f5w6fw6q 1131 3 result result NN cord-006870-f5w6fw6q 1131 4 , , , cord-006870-f5w6fw6q 1131 5 a a DT cord-006870-f5w6fw6q 1131 6 successful successful JJ cord-006870-f5w6fw6q 1131 7 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 1131 8 collaboration collaboration NN cord-006870-f5w6fw6q 1131 9 with with IN cord-006870-f5w6fw6q 1131 10 a a DT cord-006870-f5w6fw6q 1131 11 core core NN cord-006870-f5w6fw6q 1131 12 group group NN cord-006870-f5w6fw6q 1131 13 of of IN cord-006870-f5w6fw6q 1131 14 physicians physician NNS cord-006870-f5w6fw6q 1131 15 and and CC cord-006870-f5w6fw6q 1131 16 administrators administrator NNS cord-006870-f5w6fw6q 1131 17 was be VBD cord-006870-f5w6fw6q 1131 18 formed form VBN cord-006870-f5w6fw6q 1131 19 to to TO cord-006870-f5w6fw6q 1131 20 develop develop VB cord-006870-f5w6fw6q 1131 21 algorithms algorithm NNS cord-006870-f5w6fw6q 1131 22 and and CC cord-006870-f5w6fw6q 1131 23 to to TO cord-006870-f5w6fw6q 1131 24 overcome overcome VB cord-006870-f5w6fw6q 1131 25 multiple multiple JJ cord-006870-f5w6fw6q 1131 26 administrative administrative JJ cord-006870-f5w6fw6q 1131 27 and and CC cord-006870-f5w6fw6q 1131 28 legal legal JJ cord-006870-f5w6fw6q 1131 29 hurdles hurdle NNS cord-006870-f5w6fw6q 1131 30 . . . cord-006870-f5w6fw6q 1132 1 Over over IN cord-006870-f5w6fw6q 1132 2 a a DT cord-006870-f5w6fw6q 1132 3 period period NN cord-006870-f5w6fw6q 1132 4 of of IN cord-006870-f5w6fw6q 1132 5 24 24 CD cord-006870-f5w6fw6q 1132 6 months month NNS cord-006870-f5w6fw6q 1132 7 , , , cord-006870-f5w6fw6q 1132 8 multiple multiple JJ cord-006870-f5w6fw6q 1132 9 algorithms algorithm NNS cord-006870-f5w6fw6q 1132 10 were be VBD cord-006870-f5w6fw6q 1132 11 developed develop VBN cord-006870-f5w6fw6q 1132 12 to to TO cord-006870-f5w6fw6q 1132 13 systematize systematize VB cord-006870-f5w6fw6q 1132 14 Neuroscience Neuroscience NNP cord-006870-f5w6fw6q 1132 15 admissions admission NNS cord-006870-f5w6fw6q 1132 16 including include VBG cord-006870-f5w6fw6q 1132 17 Acute Acute NNP cord-006870-f5w6fw6q 1132 18 Ischemic Ischemic NNP cord-006870-f5w6fw6q 1132 19 Stroke Stroke NNP cord-006870-f5w6fw6q 1132 20 and and CC cord-006870-f5w6fw6q 1132 21 Vascular Vascular NNP cord-006870-f5w6fw6q 1132 22 and and CC cord-006870-f5w6fw6q 1132 23 Non non JJ cord-006870-f5w6fw6q 1132 24 - - JJ cord-006870-f5w6fw6q 1132 25 Vascular vascular JJ cord-006870-f5w6fw6q 1132 26 Neuroscience Neuroscience NNP cord-006870-f5w6fw6q 1132 27 emergencies emergency NNS cord-006870-f5w6fw6q 1132 28 . . . cord-006870-f5w6fw6q 1133 1 In in IN cord-006870-f5w6fw6q 1133 2 an an DT cord-006870-f5w6fw6q 1133 3 effort effort NN cord-006870-f5w6fw6q 1133 4 to to TO cord-006870-f5w6fw6q 1133 5 decrease decrease VB cord-006870-f5w6fw6q 1133 6 door door NN cord-006870-f5w6fw6q 1133 7 - - HYPH cord-006870-f5w6fw6q 1133 8 to to IN cord-006870-f5w6fw6q 1133 9 - - HYPH cord-006870-f5w6fw6q 1133 10 intervention intervention NN cord-006870-f5w6fw6q 1133 11 times time NNS cord-006870-f5w6fw6q 1133 12 as as RB cord-006870-f5w6fw6q 1133 13 well well RB cord-006870-f5w6fw6q 1133 14 as as IN cord-006870-f5w6fw6q 1133 15 effectively effectively RB cord-006870-f5w6fw6q 1133 16 mitigate mitigate VB cord-006870-f5w6fw6q 1133 17 the the DT cord-006870-f5w6fw6q 1133 18 impact impact NN cord-006870-f5w6fw6q 1133 19 of of IN cord-006870-f5w6fw6q 1133 20 limited limited JJ cord-006870-f5w6fw6q 1133 21 bed bed NN cord-006870-f5w6fw6q 1133 22 - - HYPH cord-006870-f5w6fw6q 1133 23 space space NN cord-006870-f5w6fw6q 1133 24 availability availability NN cord-006870-f5w6fw6q 1133 25 , , , cord-006870-f5w6fw6q 1133 26 this this DT cord-006870-f5w6fw6q 1133 27 system system NN cord-006870-f5w6fw6q 1133 28 now now RB cord-006870-f5w6fw6q 1133 29 serves serve VBZ cord-006870-f5w6fw6q 1133 30 3 3 CD cord-006870-f5w6fw6q 1133 31 hospitals hospital NNS cord-006870-f5w6fw6q 1133 32 including include VBG cord-006870-f5w6fw6q 1133 33 2 2 CD cord-006870-f5w6fw6q 1133 34 with with IN cord-006870-f5w6fw6q 1133 35 acute acute JJ cord-006870-f5w6fw6q 1133 36 neurointerventional neurointerventional JJ cord-006870-f5w6fw6q 1133 37 services service NNS cord-006870-f5w6fw6q 1133 38 and and CC cord-006870-f5w6fw6q 1133 39 the the DT cord-006870-f5w6fw6q 1133 40 3rd 3rd NN cord-006870-f5w6fw6q 1133 41 with with IN cord-006870-f5w6fw6q 1133 42 a a DT cord-006870-f5w6fw6q 1133 43 burgeoning burgeon VBG cord-006870-f5w6fw6q 1133 44 Neurohospitalist Neurohospitalist NNP cord-006870-f5w6fw6q 1133 45 program program NN cord-006870-f5w6fw6q 1133 46 and and CC cord-006870-f5w6fw6q 1133 47 incorporated incorporate VBN cord-006870-f5w6fw6q 1133 48 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 1133 49 services service NNS cord-006870-f5w6fw6q 1133 50 . . . cord-006870-f5w6fw6q 1134 1 In in IN cord-006870-f5w6fw6q 1134 2 addition addition NN cord-006870-f5w6fw6q 1134 3 to to IN cord-006870-f5w6fw6q 1134 4 systematizing systematize VBG cord-006870-f5w6fw6q 1134 5 the the DT cord-006870-f5w6fw6q 1134 6 transfer transfer NN cord-006870-f5w6fw6q 1134 7 and and CC cord-006870-f5w6fw6q 1134 8 admission admission NN cord-006870-f5w6fw6q 1134 9 process process NN cord-006870-f5w6fw6q 1134 10 , , , cord-006870-f5w6fw6q 1134 11 quality quality NN cord-006870-f5w6fw6q 1134 12 assurance assurance NN cord-006870-f5w6fw6q 1134 13 , , , cord-006870-f5w6fw6q 1134 14 improvement improvement NN cord-006870-f5w6fw6q 1134 15 , , , cord-006870-f5w6fw6q 1134 16 and and CC cord-006870-f5w6fw6q 1134 17 educational educational JJ cord-006870-f5w6fw6q 1134 18 processes process NNS cord-006870-f5w6fw6q 1134 19 are be VBP cord-006870-f5w6fw6q 1134 20 in in IN cord-006870-f5w6fw6q 1134 21 a a DT cord-006870-f5w6fw6q 1134 22 place place NN cord-006870-f5w6fw6q 1134 23 . . . cord-006870-f5w6fw6q 1135 1 The the DT cord-006870-f5w6fw6q 1135 2 current current JJ cord-006870-f5w6fw6q 1135 3 state state NN cord-006870-f5w6fw6q 1135 4 of of IN cord-006870-f5w6fw6q 1135 5 PHAST PHAST NNP cord-006870-f5w6fw6q 1135 6 is be VBZ cord-006870-f5w6fw6q 1135 7 that that DT cord-006870-f5w6fw6q 1135 8 of of IN cord-006870-f5w6fw6q 1135 9 a a DT cord-006870-f5w6fw6q 1135 10 young young JJ cord-006870-f5w6fw6q 1135 11 but but CC cord-006870-f5w6fw6q 1135 12 maturing maturing JJ cord-006870-f5w6fw6q 1135 13 and and CC cord-006870-f5w6fw6q 1135 14 now now RB cord-006870-f5w6fw6q 1135 15 essential essential JJ cord-006870-f5w6fw6q 1135 16 service service NN cord-006870-f5w6fw6q 1135 17 for for IN cord-006870-f5w6fw6q 1135 18 Duke Duke NNP cord-006870-f5w6fw6q 1135 19 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 1135 20 . . . cord-006870-f5w6fw6q 1136 1 Extubation extubation NN cord-006870-f5w6fw6q 1136 2 involves involve VBZ cord-006870-f5w6fw6q 1136 3 removal removal NN cord-006870-f5w6fw6q 1136 4 of of IN cord-006870-f5w6fw6q 1136 5 an an DT cord-006870-f5w6fw6q 1136 6 endotracheal endotracheal NN cord-006870-f5w6fw6q 1136 7 tube tube NN cord-006870-f5w6fw6q 1136 8 ( ( -LRB- cord-006870-f5w6fw6q 1136 9 ETT ETT NNP cord-006870-f5w6fw6q 1136 10 ) ) -RRB- cord-006870-f5w6fw6q 1136 11 and and CC cord-006870-f5w6fw6q 1136 12 is be VBZ cord-006870-f5w6fw6q 1136 13 a a DT cord-006870-f5w6fw6q 1136 14 common common JJ cord-006870-f5w6fw6q 1136 15 intensive intensive JJ cord-006870-f5w6fw6q 1136 16 care care NN cord-006870-f5w6fw6q 1136 17 unit unit NN cord-006870-f5w6fw6q 1136 18 ( ( -LRB- cord-006870-f5w6fw6q 1136 19 ICU ICU NNP cord-006870-f5w6fw6q 1136 20 ) ) -RRB- cord-006870-f5w6fw6q 1136 21 procedure procedure NN cord-006870-f5w6fw6q 1136 22 . . . cord-006870-f5w6fw6q 1137 1 Extubation extubation NN cord-006870-f5w6fw6q 1137 2 failure failure NN cord-006870-f5w6fw6q 1137 3 occurs occur VBZ cord-006870-f5w6fw6q 1137 4 in in IN cord-006870-f5w6fw6q 1137 5 8 8 CD cord-006870-f5w6fw6q 1137 6 - - SYM cord-006870-f5w6fw6q 1137 7 20 20 CD cord-006870-f5w6fw6q 1137 8 % % NN cord-006870-f5w6fw6q 1137 9 of of IN cord-006870-f5w6fw6q 1137 10 ICU ICU NNP cord-006870-f5w6fw6q 1137 11 patients patient NNS cord-006870-f5w6fw6q 1137 12 and and CC cord-006870-f5w6fw6q 1137 13 can can MD cord-006870-f5w6fw6q 1137 14 be be VB cord-006870-f5w6fw6q 1137 15 difficult difficult JJ cord-006870-f5w6fw6q 1137 16 to to TO cord-006870-f5w6fw6q 1137 17 predict predict VB cord-006870-f5w6fw6q 1137 18 accurately accurately RB cord-006870-f5w6fw6q 1137 19 . . . cord-006870-f5w6fw6q 1138 1 We -PRON- PRP cord-006870-f5w6fw6q 1138 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 1138 3 that that IN cord-006870-f5w6fw6q 1138 4 a a DT cord-006870-f5w6fw6q 1138 5 multivariate multivariate JJ cord-006870-f5w6fw6q 1138 6 Re re NN cord-006870-f5w6fw6q 1138 7 - - HYPH cord-006870-f5w6fw6q 1138 8 Intubation Intubation NNP cord-006870-f5w6fw6q 1138 9 Scale scale NN cord-006870-f5w6fw6q 1138 10 Calculation Calculation NNP cord-006870-f5w6fw6q 1138 11 ( ( -LRB- cord-006870-f5w6fw6q 1138 12 RISC RISC NNP cord-006870-f5w6fw6q 1138 13 ) ) -RRB- cord-006870-f5w6fw6q 1138 14 model model NN cord-006870-f5w6fw6q 1138 15 could could MD cord-006870-f5w6fw6q 1138 16 predict predict VB cord-006870-f5w6fw6q 1138 17 extubation extubation NN cord-006870-f5w6fw6q 1138 18 failure failure NN cord-006870-f5w6fw6q 1138 19 better well JJR cord-006870-f5w6fw6q 1138 20 than than IN cord-006870-f5w6fw6q 1138 21 a a DT cord-006870-f5w6fw6q 1138 22 single single JJ cord-006870-f5w6fw6q 1138 23 variable variable NN cord-006870-f5w6fw6q 1138 24 like like IN cord-006870-f5w6fw6q 1138 25 Rapid Rapid NNP cord-006870-f5w6fw6q 1138 26 Shallow Shallow NNP cord-006870-f5w6fw6q 1138 27 Breathing Breathing NNP cord-006870-f5w6fw6q 1138 28 Index Index NNP cord-006870-f5w6fw6q 1138 29 ( ( -LRB- cord-006870-f5w6fw6q 1138 30 RSBI RSBI NNP cord-006870-f5w6fw6q 1138 31 ) ) -RRB- cord-006870-f5w6fw6q 1138 32 . . . cord-006870-f5w6fw6q 1139 1 After after IN cord-006870-f5w6fw6q 1139 2 IRB IRB NNP cord-006870-f5w6fw6q 1139 3 approval approval NN cord-006870-f5w6fw6q 1139 4 , , , cord-006870-f5w6fw6q 1139 5 we -PRON- PRP cord-006870-f5w6fw6q 1139 6 conducted conduct VBD cord-006870-f5w6fw6q 1139 7 a a DT cord-006870-f5w6fw6q 1139 8 retrospective retrospective JJ cord-006870-f5w6fw6q 1139 9 review review NN cord-006870-f5w6fw6q 1139 10 of of IN cord-006870-f5w6fw6q 1139 11 data datum NNS cord-006870-f5w6fw6q 1139 12 on on IN cord-006870-f5w6fw6q 1139 13 mechanically mechanically RB cord-006870-f5w6fw6q 1139 14 ventilated ventilate VBN cord-006870-f5w6fw6q 1139 15 ICU ICU NNP cord-006870-f5w6fw6q 1139 16 patients patient NNS cord-006870-f5w6fw6q 1139 17 above above IN cord-006870-f5w6fw6q 1139 18 18 18 CD cord-006870-f5w6fw6q 1139 19 years year NNS cord-006870-f5w6fw6q 1139 20 of of IN cord-006870-f5w6fw6q 1139 21 age age NN cord-006870-f5w6fw6q 1139 22 who who WP cord-006870-f5w6fw6q 1139 23 were be VBD cord-006870-f5w6fw6q 1139 24 not not RB cord-006870-f5w6fw6q 1139 25 receiving receive VBG cord-006870-f5w6fw6q 1139 26 mechanical mechanical JJ cord-006870-f5w6fw6q 1139 27 ventilation ventilation NN cord-006870-f5w6fw6q 1139 28 through through IN cord-006870-f5w6fw6q 1139 29 a a DT cord-006870-f5w6fw6q 1139 30 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 1139 31 tube tube NN cord-006870-f5w6fw6q 1139 32 from from IN cord-006870-f5w6fw6q 1139 33 January January NNP cord-006870-f5w6fw6q 1139 34 1 1 CD cord-006870-f5w6fw6q 1139 35 , , , cord-006870-f5w6fw6q 1139 36 2006 2006 CD cord-006870-f5w6fw6q 1139 37 , , , cord-006870-f5w6fw6q 1139 38 through through IN cord-006870-f5w6fw6q 1139 39 December December NNP cord-006870-f5w6fw6q 1139 40 31 31 CD cord-006870-f5w6fw6q 1139 41 , , , cord-006870-f5w6fw6q 1139 42 2015 2015 CD cord-006870-f5w6fw6q 1139 43 at at IN cord-006870-f5w6fw6q 1139 44 Mayo Mayo NNP cord-006870-f5w6fw6q 1139 45 Clinic Clinic NNP cord-006870-f5w6fw6q 1139 46 Rochester Rochester NNP cord-006870-f5w6fw6q 1139 47 . . . cord-006870-f5w6fw6q 1140 1 Various various JJ cord-006870-f5w6fw6q 1140 2 data data NN cord-006870-f5w6fw6q 1140 3 points point NNS cord-006870-f5w6fw6q 1140 4 were be VBD cord-006870-f5w6fw6q 1140 5 gathered gather VBN cord-006870-f5w6fw6q 1140 6 on on IN cord-006870-f5w6fw6q 1140 7 these these DT cord-006870-f5w6fw6q 1140 8 patients patient NNS cord-006870-f5w6fw6q 1140 9 via via IN cord-006870-f5w6fw6q 1140 10 electronic electronic JJ cord-006870-f5w6fw6q 1140 11 medical medical JJ cord-006870-f5w6fw6q 1140 12 records record NNS cord-006870-f5w6fw6q 1140 13 search search NN cord-006870-f5w6fw6q 1140 14 , , , cord-006870-f5w6fw6q 1140 15 and and CC cord-006870-f5w6fw6q 1140 16 reintubations reintubation NNS cord-006870-f5w6fw6q 1140 17 within within IN cord-006870-f5w6fw6q 1140 18 72 72 CD cord-006870-f5w6fw6q 1140 19 hours hour NNS cord-006870-f5w6fw6q 1140 20 of of IN cord-006870-f5w6fw6q 1140 21 extubation extubation NN cord-006870-f5w6fw6q 1140 22 were be VBD cord-006870-f5w6fw6q 1140 23 identified identify VBN cord-006870-f5w6fw6q 1140 24 . . . cord-006870-f5w6fw6q 1141 1 Univariate univariate JJ cord-006870-f5w6fw6q 1141 2 and and CC cord-006870-f5w6fw6q 1141 3 multivariate multivariate JJ cord-006870-f5w6fw6q 1141 4 logistic logistic JJ cord-006870-f5w6fw6q 1141 5 regression regression NN cord-006870-f5w6fw6q 1141 6 models model NNS cord-006870-f5w6fw6q 1141 7 were be VBD cord-006870-f5w6fw6q 1141 8 used use VBN cord-006870-f5w6fw6q 1141 9 to to TO cord-006870-f5w6fw6q 1141 10 predict predict VB cord-006870-f5w6fw6q 1141 11 reintubation reintubation NN cord-006870-f5w6fw6q 1141 12 after after IN cord-006870-f5w6fw6q 1141 13 extubation extubation NN cord-006870-f5w6fw6q 1141 14 and and CC cord-006870-f5w6fw6q 1141 15 construct construct VB cord-006870-f5w6fw6q 1141 16 a a DT cord-006870-f5w6fw6q 1141 17 RISC RISC NNP cord-006870-f5w6fw6q 1141 18 estimate estimate NN cord-006870-f5w6fw6q 1141 19 . . . cord-006870-f5w6fw6q 1142 1 We -PRON- PRP cord-006870-f5w6fw6q 1142 2 included include VBD cord-006870-f5w6fw6q 1142 3 a a DT cord-006870-f5w6fw6q 1142 4 total total NN cord-006870-f5w6fw6q 1142 5 of of IN cord-006870-f5w6fw6q 1142 6 6161 6161 CD cord-006870-f5w6fw6q 1142 7 patients patient NNS cord-006870-f5w6fw6q 1142 8 which which WDT cord-006870-f5w6fw6q 1142 9 were be VBD cord-006870-f5w6fw6q 1142 10 randomly randomly RB cord-006870-f5w6fw6q 1142 11 divided divide VBN cord-006870-f5w6fw6q 1142 12 into into IN cord-006870-f5w6fw6q 1142 13 a a DT cord-006870-f5w6fw6q 1142 14 derivation derivation NN cord-006870-f5w6fw6q 1142 15 set set NN cord-006870-f5w6fw6q 1142 16 ( ( -LRB- cord-006870-f5w6fw6q 1142 17 N=3080 N=3080 NNP cord-006870-f5w6fw6q 1142 18 ) ) -RRB- cord-006870-f5w6fw6q 1142 19 and and CC cord-006870-f5w6fw6q 1142 20 validation validation NN cord-006870-f5w6fw6q 1142 21 set set NN cord-006870-f5w6fw6q 1142 22 ( ( -LRB- cord-006870-f5w6fw6q 1142 23 N=3081 N=3081 NNP cord-006870-f5w6fw6q 1142 24 ) ) -RRB- cord-006870-f5w6fw6q 1142 25 . . . cord-006870-f5w6fw6q 1143 1 In in IN cord-006870-f5w6fw6q 1143 2 the the DT cord-006870-f5w6fw6q 1143 3 derivation derivation NN cord-006870-f5w6fw6q 1143 4 set set VBN cord-006870-f5w6fw6q 1143 5 , , , cord-006870-f5w6fw6q 1143 6 patients patient NNS cord-006870-f5w6fw6q 1143 7 had have VBD cord-006870-f5w6fw6q 1143 8 a a DT cord-006870-f5w6fw6q 1143 9 mean mean JJ cord-006870-f5w6fw6q 1143 10 age age NN cord-006870-f5w6fw6q 1143 11 of of IN cord-006870-f5w6fw6q 1143 12 62±17 62±17 CD cord-006870-f5w6fw6q 1143 13 years year NNS cord-006870-f5w6fw6q 1143 14 , , , cord-006870-f5w6fw6q 1143 15 and and CC cord-006870-f5w6fw6q 1143 16 59 59 CD cord-006870-f5w6fw6q 1143 17 % % NN cord-006870-f5w6fw6q 1143 18 were be VBD cord-006870-f5w6fw6q 1143 19 men man NNS cord-006870-f5w6fw6q 1143 20 . . . cord-006870-f5w6fw6q 1144 1 Three three CD cord-006870-f5w6fw6q 1144 2 hundred hundred CD cord-006870-f5w6fw6q 1144 3 and and CC cord-006870-f5w6fw6q 1144 4 ninety ninety CD cord-006870-f5w6fw6q 1144 5 three three CD cord-006870-f5w6fw6q 1144 6 extubation extubation NN cord-006870-f5w6fw6q 1144 7 failures failure NNS cord-006870-f5w6fw6q 1144 8 occurred occur VBD cord-006870-f5w6fw6q 1144 9 within within IN cord-006870-f5w6fw6q 1144 10 72 72 CD cord-006870-f5w6fw6q 1144 11 hours hour NNS cord-006870-f5w6fw6q 1144 12 . . . cord-006870-f5w6fw6q 1145 1 Predictors predictor NNS cord-006870-f5w6fw6q 1145 2 of of IN cord-006870-f5w6fw6q 1145 3 extubation extubation NN cord-006870-f5w6fw6q 1145 4 failure failure NN cord-006870-f5w6fw6q 1145 5 included include VBD cord-006870-f5w6fw6q 1145 6 underweight underweight JJ cord-006870-f5w6fw6q 1145 7 status status NN cord-006870-f5w6fw6q 1145 8 , , , cord-006870-f5w6fw6q 1145 9 GCS GCS NNP cord-006870-f5w6fw6q 1145 10 score>=10 score>=10 NNP cord-006870-f5w6fw6q 1145 11 , , , cord-006870-f5w6fw6q 1145 12 mean mean VB cord-006870-f5w6fw6q 1145 13 airway airway NN cord-006870-f5w6fw6q 1145 14 pressure pressure NN cord-006870-f5w6fw6q 1145 15 at at IN cord-006870-f5w6fw6q 1145 16 1 1 CD cord-006870-f5w6fw6q 1145 17 minute=1500mL minute=1500mL NNP cord-006870-f5w6fw6q 1145 18 and and CC cord-006870-f5w6fw6q 1145 19 total total JJ cord-006870-f5w6fw6q 1145 20 mechanical mechanical JJ cord-006870-f5w6fw6q 1145 21 ventilation ventilation NN cord-006870-f5w6fw6q 1145 22 days>=5 days>=5 NN cord-006870-f5w6fw6q 1145 23 in in IN cord-006870-f5w6fw6q 1145 24 the the DT cord-006870-f5w6fw6q 1145 25 final final JJ cord-006870-f5w6fw6q 1145 26 multivariable multivariable JJ cord-006870-f5w6fw6q 1145 27 model model NN cord-006870-f5w6fw6q 1145 28 . . . cord-006870-f5w6fw6q 1146 1 RISC RISC NNP cord-006870-f5w6fw6q 1146 2 score score NN cord-006870-f5w6fw6q 1146 3 was be VBD cord-006870-f5w6fw6q 1146 4 calculated calculate VBN cord-006870-f5w6fw6q 1146 5 using use VBG cord-006870-f5w6fw6q 1146 6 the the DT cord-006870-f5w6fw6q 1146 7 validation validation NN cord-006870-f5w6fw6q 1146 8 set set VBN cord-006870-f5w6fw6q 1146 9 and and CC cord-006870-f5w6fw6q 1146 10 ranged range VBD cord-006870-f5w6fw6q 1146 11 from from IN cord-006870-f5w6fw6q 1146 12 0 0 CD cord-006870-f5w6fw6q 1146 13 to to IN cord-006870-f5w6fw6q 1146 14 8 8 CD cord-006870-f5w6fw6q 1146 15 . . . cord-006870-f5w6fw6q 1147 1 Logistic logistic JJ cord-006870-f5w6fw6q 1147 2 model model NN cord-006870-f5w6fw6q 1147 3 result result NN cord-006870-f5w6fw6q 1147 4 shows show VBZ cord-006870-f5w6fw6q 1147 5 that that IN cord-006870-f5w6fw6q 1147 6 , , , cord-006870-f5w6fw6q 1147 7 as as IN cord-006870-f5w6fw6q 1147 8 RISC RISC NNP cord-006870-f5w6fw6q 1147 9 increased increase VBD cord-006870-f5w6fw6q 1147 10 by by IN cord-006870-f5w6fw6q 1147 11 1 1 CD cord-006870-f5w6fw6q 1147 12 , , , cord-006870-f5w6fw6q 1147 13 the the DT cord-006870-f5w6fw6q 1147 14 odds odd NNS cord-006870-f5w6fw6q 1147 15 of of IN cord-006870-f5w6fw6q 1147 16 having have VBG cord-006870-f5w6fw6q 1147 17 extubation extubation NN cord-006870-f5w6fw6q 1147 18 failure failure NN cord-006870-f5w6fw6q 1147 19 was be VBD cord-006870-f5w6fw6q 1147 20 1.6 1.6 CD cord-006870-f5w6fw6q 1147 21 fold fold VB cord-006870-f5w6fw6q 1147 22 higher higher RBR cord-006870-f5w6fw6q 1147 23 ( ( -LRB- cord-006870-f5w6fw6q 1147 24 C C NNP cord-006870-f5w6fw6q 1147 25 - - HYPH cord-006870-f5w6fw6q 1147 26 index=0.72 index=0.72 NNP cord-006870-f5w6fw6q 1147 27 ) ) -RRB- cord-006870-f5w6fw6q 1147 28 . . . cord-006870-f5w6fw6q 1148 1 ROC ROC NNP cord-006870-f5w6fw6q 1148 2 analysis analysis NN cord-006870-f5w6fw6q 1148 3 shows show VBZ cord-006870-f5w6fw6q 1148 4 that that IN cord-006870-f5w6fw6q 1148 5 the the DT cord-006870-f5w6fw6q 1148 6 best good JJS cord-006870-f5w6fw6q 1148 7 cut cut VBN cord-006870-f5w6fw6q 1148 8 off off RP cord-006870-f5w6fw6q 1148 9 for for IN cord-006870-f5w6fw6q 1148 10 RISC RISC NNP cord-006870-f5w6fw6q 1148 11 was be VBD cord-006870-f5w6fw6q 1148 12 > > XX cord-006870-f5w6fw6q 1148 13 = = SYM cord-006870-f5w6fw6q 1148 14 4 4 CD cord-006870-f5w6fw6q 1148 15 vs. vs. NN cord-006870-f5w6fw6q 1148 16 < < NNP cord-006870-f5w6fw6q 1148 17 4 4 CD cord-006870-f5w6fw6q 1148 18 , , , cord-006870-f5w6fw6q 1148 19 which which WDT cord-006870-f5w6fw6q 1148 20 demonstrated demonstrate VBD cord-006870-f5w6fw6q 1148 21 a a DT cord-006870-f5w6fw6q 1148 22 sensitivity sensitivity NN cord-006870-f5w6fw6q 1148 23 of of IN cord-006870-f5w6fw6q 1148 24 0.80 0.80 CD cord-006870-f5w6fw6q 1148 25 , , , cord-006870-f5w6fw6q 1148 26 specificity specificity NN cord-006870-f5w6fw6q 1148 27 of of IN cord-006870-f5w6fw6q 1148 28 0.54 0.54 CD cord-006870-f5w6fw6q 1148 29 and and CC cord-006870-f5w6fw6q 1148 30 AUC=0.67 AUC=0.67 NNP cord-006870-f5w6fw6q 1148 31 . . . cord-006870-f5w6fw6q 1149 1 The the DT cord-006870-f5w6fw6q 1149 2 current current JJ cord-006870-f5w6fw6q 1149 3 RISC RISC NNP cord-006870-f5w6fw6q 1149 4 model model NN cord-006870-f5w6fw6q 1149 5 warrants warrant NNS cord-006870-f5w6fw6q 1149 6 further further JJ cord-006870-f5w6fw6q 1149 7 exploration exploration NN cord-006870-f5w6fw6q 1149 8 in in IN cord-006870-f5w6fw6q 1149 9 a a DT cord-006870-f5w6fw6q 1149 10 prospective prospective JJ cord-006870-f5w6fw6q 1149 11 study study NN cord-006870-f5w6fw6q 1149 12 to to TO cord-006870-f5w6fw6q 1149 13 help help VB cord-006870-f5w6fw6q 1149 14 critical critical JJ cord-006870-f5w6fw6q 1149 15 care care NN cord-006870-f5w6fw6q 1149 16 providers provider NNS cord-006870-f5w6fw6q 1149 17 to to TO cord-006870-f5w6fw6q 1149 18 decide decide VB cord-006870-f5w6fw6q 1149 19 when when WRB cord-006870-f5w6fw6q 1149 20 extubation extubation NN cord-006870-f5w6fw6q 1149 21 can can MD cord-006870-f5w6fw6q 1149 22 be be VB cord-006870-f5w6fw6q 1149 23 done do VBN cord-006870-f5w6fw6q 1149 24 more more RBR cord-006870-f5w6fw6q 1149 25 safely safely RB cord-006870-f5w6fw6q 1149 26 . . . cord-006870-f5w6fw6q 1150 1 This this DT cord-006870-f5w6fw6q 1150 2 report report NN cord-006870-f5w6fw6q 1150 3 presents present VBZ cord-006870-f5w6fw6q 1150 4 results result NNS cord-006870-f5w6fw6q 1150 5 of of IN cord-006870-f5w6fw6q 1150 6 the the DT cord-006870-f5w6fw6q 1150 7 2nd 2nd JJ cord-006870-f5w6fw6q 1150 8 nationwide nationwide JJ cord-006870-f5w6fw6q 1150 9 survey survey NN cord-006870-f5w6fw6q 1150 10 concerning concern VBG cord-006870-f5w6fw6q 1150 11 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1150 12 care care NN cord-006870-f5w6fw6q 1150 13 units unit NNS cord-006870-f5w6fw6q 1150 14 ( ( -LRB- cord-006870-f5w6fw6q 1150 15 NCUs NCUs NNP cord-006870-f5w6fw6q 1150 16 ) ) -RRB- cord-006870-f5w6fw6q 1150 17 in in IN cord-006870-f5w6fw6q 1150 18 China China NNP cord-006870-f5w6fw6q 1150 19 . . . cord-006870-f5w6fw6q 1151 1 This this DT cord-006870-f5w6fw6q 1151 2 is be VBZ cord-006870-f5w6fw6q 1151 3 an an DT cord-006870-f5w6fw6q 1151 4 observational observational JJ cord-006870-f5w6fw6q 1151 5 cross cross JJ cord-006870-f5w6fw6q 1151 6 - - JJ cord-006870-f5w6fw6q 1151 7 sectional sectional JJ cord-006870-f5w6fw6q 1151 8 survey survey NN cord-006870-f5w6fw6q 1151 9 and and CC cord-006870-f5w6fw6q 1151 10 close close RB cord-006870-f5w6fw6q 1151 11 - - HYPH cord-006870-f5w6fw6q 1151 12 ended end VBN cord-006870-f5w6fw6q 1151 13 self self NN cord-006870-f5w6fw6q 1151 14 - - HYPH cord-006870-f5w6fw6q 1151 15 reported report VBN cord-006870-f5w6fw6q 1151 16 questions question NNS cord-006870-f5w6fw6q 1151 17 were be VBD cord-006870-f5w6fw6q 1151 18 used use VBN cord-006870-f5w6fw6q 1151 19 . . . cord-006870-f5w6fw6q 1152 1 The the DT cord-006870-f5w6fw6q 1152 2 questionnaire questionnaire NN cord-006870-f5w6fw6q 1152 3 was be VBD cord-006870-f5w6fw6q 1152 4 sent send VBN cord-006870-f5w6fw6q 1152 5 to to IN cord-006870-f5w6fw6q 1152 6 31 31 CD cord-006870-f5w6fw6q 1152 7 different different JJ cord-006870-f5w6fw6q 1152 8 provinces province NNS cord-006870-f5w6fw6q 1152 9 ( ( -LRB- cord-006870-f5w6fw6q 1152 10 autonomous autonomous JJ cord-006870-f5w6fw6q 1152 11 regions region NNS cord-006870-f5w6fw6q 1152 12 and and CC cord-006870-f5w6fw6q 1152 13 municipalities municipality NNS cord-006870-f5w6fw6q 1152 14 ) ) -RRB- cord-006870-f5w6fw6q 1152 15 across across IN cord-006870-f5w6fw6q 1152 16 China China NNP cord-006870-f5w6fw6q 1152 17 from from IN cord-006870-f5w6fw6q 1152 18 October October NNP cord-006870-f5w6fw6q 1152 19 1st 1st NN cord-006870-f5w6fw6q 1152 20 , , , cord-006870-f5w6fw6q 1152 21 2015 2015 CD cord-006870-f5w6fw6q 1152 22 to to IN cord-006870-f5w6fw6q 1152 23 January January NNP cord-006870-f5w6fw6q 1152 24 1st 1st NN cord-006870-f5w6fw6q 1152 25 , , , cord-006870-f5w6fw6q 1152 26 2016 2016 CD cord-006870-f5w6fw6q 1152 27 . . . cord-006870-f5w6fw6q 1153 1 Basic basic JJ cord-006870-f5w6fw6q 1153 2 information information NN cord-006870-f5w6fw6q 1153 3 , , , cord-006870-f5w6fw6q 1153 4 equipment equipment NN cord-006870-f5w6fw6q 1153 5 and and CC cord-006870-f5w6fw6q 1153 6 device device NN cord-006870-f5w6fw6q 1153 7 information information NN cord-006870-f5w6fw6q 1153 8 , , , cord-006870-f5w6fw6q 1153 9 and and CC cord-006870-f5w6fw6q 1153 10 staffing staffing NN cord-006870-f5w6fw6q 1153 11 and and CC cord-006870-f5w6fw6q 1153 12 organization organization NN cord-006870-f5w6fw6q 1153 13 information information NN cord-006870-f5w6fw6q 1153 14 were be VBD cord-006870-f5w6fw6q 1153 15 investigated investigate VBN cord-006870-f5w6fw6q 1153 16 . . . cord-006870-f5w6fw6q 1154 1 In in IN cord-006870-f5w6fw6q 1154 2 total total NN cord-006870-f5w6fw6q 1154 3 , , , cord-006870-f5w6fw6q 1154 4 101 101 CD cord-006870-f5w6fw6q 1154 5 questionnaires questionnaire NNS cord-006870-f5w6fw6q 1154 6 from from IN cord-006870-f5w6fw6q 1154 7 101 101 CD cord-006870-f5w6fw6q 1154 8 NCUs ncus NN cord-006870-f5w6fw6q 1154 9 at at IN cord-006870-f5w6fw6q 1154 10 92 92 CD cord-006870-f5w6fw6q 1154 11 hospitals hospital NNS cord-006870-f5w6fw6q 1154 12 in in IN cord-006870-f5w6fw6q 1154 13 28 28 CD cord-006870-f5w6fw6q 1154 14 regions region NNS cord-006870-f5w6fw6q 1154 15 were be VBD cord-006870-f5w6fw6q 1154 16 received receive VBN cord-006870-f5w6fw6q 1154 17 . . . cord-006870-f5w6fw6q 1155 1 Most Most JJS cord-006870-f5w6fw6q 1155 2 of of IN cord-006870-f5w6fw6q 1155 3 the the DT cord-006870-f5w6fw6q 1155 4 hospitals hospital NNS cord-006870-f5w6fw6q 1155 5 with with IN cord-006870-f5w6fw6q 1155 6 NCUs NCUs NNP cord-006870-f5w6fw6q 1155 7 were be VBD cord-006870-f5w6fw6q 1155 8 large large JJ cord-006870-f5w6fw6q 1155 9 - - HYPH cord-006870-f5w6fw6q 1155 10 scale scale NN cord-006870-f5w6fw6q 1155 11 ( ( -LRB- cord-006870-f5w6fw6q 1155 12 average average JJ cord-006870-f5w6fw6q 1155 13 hospital hospital NN cord-006870-f5w6fw6q 1155 14 beds bed NNS cord-006870-f5w6fw6q 1155 15 : : : cord-006870-f5w6fw6q 1155 16 2150 2150 CD cord-006870-f5w6fw6q 1155 17 ) ) -RRB- cord-006870-f5w6fw6q 1155 18 , , , cord-006870-f5w6fw6q 1155 19 teaching teaching NN cord-006870-f5w6fw6q 1155 20 ( ( -LRB- cord-006870-f5w6fw6q 1155 21 84.8 84.8 CD cord-006870-f5w6fw6q 1155 22 % % NN cord-006870-f5w6fw6q 1155 23 ) ) -RRB- cord-006870-f5w6fw6q 1155 24 , , , cord-006870-f5w6fw6q 1155 25 and and CC cord-006870-f5w6fw6q 1155 26 tertiary tertiary JJ cord-006870-f5w6fw6q 1155 27 hospitals hospital NNS cord-006870-f5w6fw6q 1155 28 ( ( -LRB- cord-006870-f5w6fw6q 1155 29 97.8 97.8 CD cord-006870-f5w6fw6q 1155 30 % % NN cord-006870-f5w6fw6q 1155 31 ) ) -RRB- cord-006870-f5w6fw6q 1155 32 . . . cord-006870-f5w6fw6q 1156 1 The the DT cord-006870-f5w6fw6q 1156 2 average average JJ cord-006870-f5w6fw6q 1156 3 number number NN cord-006870-f5w6fw6q 1156 4 of of IN cord-006870-f5w6fw6q 1156 5 NCU NCU NNP cord-006870-f5w6fw6q 1156 6 beds bed NNS cord-006870-f5w6fw6q 1156 7 was be VBD cord-006870-f5w6fw6q 1156 8 14 14 CD cord-006870-f5w6fw6q 1156 9 , , , cord-006870-f5w6fw6q 1156 10 occupying occupy VBG cord-006870-f5w6fw6q 1156 11 11.2 11.2 CD cord-006870-f5w6fw6q 1156 12 % % NN cord-006870-f5w6fw6q 1156 13 of of IN cord-006870-f5w6fw6q 1156 14 the the DT cord-006870-f5w6fw6q 1156 15 total total JJ cord-006870-f5w6fw6q 1156 16 number number NN cord-006870-f5w6fw6q 1156 17 of of IN cord-006870-f5w6fw6q 1156 18 beds bed NNS cord-006870-f5w6fw6q 1156 19 in in IN cord-006870-f5w6fw6q 1156 20 their -PRON- PRP$ cord-006870-f5w6fw6q 1156 21 department department NN cord-006870-f5w6fw6q 1156 22 . . . cord-006870-f5w6fw6q 1157 1 Most Most JJS cord-006870-f5w6fw6q 1157 2 of of IN cord-006870-f5w6fw6q 1157 3 the the DT cord-006870-f5w6fw6q 1157 4 equipment equipment NN cord-006870-f5w6fw6q 1157 5 and and CC cord-006870-f5w6fw6q 1157 6 devices device NNS cord-006870-f5w6fw6q 1157 7 ( ( -LRB- cord-006870-f5w6fw6q 1157 8 37/50 37/50 CD cord-006870-f5w6fw6q 1157 9 ) ) -RRB- cord-006870-f5w6fw6q 1157 10 were be VBD cord-006870-f5w6fw6q 1157 11 available available JJ cord-006870-f5w6fw6q 1157 12 in in IN cord-006870-f5w6fw6q 1157 13 over over IN cord-006870-f5w6fw6q 1157 14 80 80 CD cord-006870-f5w6fw6q 1157 15 % % NN cord-006870-f5w6fw6q 1157 16 of of IN cord-006870-f5w6fw6q 1157 17 the the DT cord-006870-f5w6fw6q 1157 18 101 101 CD cord-006870-f5w6fw6q 1157 19 NCUs ncus NN cord-006870-f5w6fw6q 1157 20 . . . cord-006870-f5w6fw6q 1158 1 However however RB cord-006870-f5w6fw6q 1158 2 , , , cord-006870-f5w6fw6q 1158 3 some some DT cord-006870-f5w6fw6q 1158 4 devices device NNS cord-006870-f5w6fw6q 1158 5 were be VBD cord-006870-f5w6fw6q 1158 6 centralized centralize VBN cord-006870-f5w6fw6q 1158 7 by by IN cord-006870-f5w6fw6q 1158 8 hospital hospital NN cord-006870-f5w6fw6q 1158 9 and and CC cord-006870-f5w6fw6q 1158 10 operated operate VBN cord-006870-f5w6fw6q 1158 11 with with IN cord-006870-f5w6fw6q 1158 12 assistance assistance NN cord-006870-f5w6fw6q 1158 13 from from IN cord-006870-f5w6fw6q 1158 14 other other JJ cord-006870-f5w6fw6q 1158 15 departments department NNS cord-006870-f5w6fw6q 1158 16 . . . cord-006870-f5w6fw6q 1159 1 A a DT cord-006870-f5w6fw6q 1159 2 total total NN cord-006870-f5w6fw6q 1159 3 of of IN cord-006870-f5w6fw6q 1159 4 1250 1250 CD cord-006870-f5w6fw6q 1159 5 full full JJ cord-006870-f5w6fw6q 1159 6 - - HYPH cord-006870-f5w6fw6q 1159 7 time time NN cord-006870-f5w6fw6q 1159 8 doctors doctor NNS cord-006870-f5w6fw6q 1159 9 and and CC cord-006870-f5w6fw6q 1159 10 1978 1978 CD cord-006870-f5w6fw6q 1159 11 full full JJ cord-006870-f5w6fw6q 1159 12 - - HYPH cord-006870-f5w6fw6q 1159 13 time time NN cord-006870-f5w6fw6q 1159 14 nurses nurse NNS cord-006870-f5w6fw6q 1159 15 were be VBD cord-006870-f5w6fw6q 1159 16 employed employ VBN cord-006870-f5w6fw6q 1159 17 at at IN cord-006870-f5w6fw6q 1159 18 the the DT cord-006870-f5w6fw6q 1159 19 NCUs NCUs NNP cord-006870-f5w6fw6q 1159 20 . . . cord-006870-f5w6fw6q 1160 1 A a DT cord-006870-f5w6fw6q 1160 2 few few JJ cord-006870-f5w6fw6q 1160 3 of of IN cord-006870-f5w6fw6q 1160 4 the the DT cord-006870-f5w6fw6q 1160 5 NCUs NCUs NNP cord-006870-f5w6fw6q 1160 6 achieved achieve VBD cord-006870-f5w6fw6q 1160 7 a a DT cord-006870-f5w6fw6q 1160 8 doctor doctor NN cord-006870-f5w6fw6q 1160 9 - - HYPH cord-006870-f5w6fw6q 1160 10 to to IN cord-006870-f5w6fw6q 1160 11 - - HYPH cord-006870-f5w6fw6q 1160 12 bed bed NN cord-006870-f5w6fw6q 1160 13 ratio ratio NN cord-006870-f5w6fw6q 1160 14 of of IN cord-006870-f5w6fw6q 1160 15 0.5:1 0.5:1 CD cord-006870-f5w6fw6q 1160 16 ( ( -LRB- cord-006870-f5w6fw6q 1160 17 40.6 40.6 CD cord-006870-f5w6fw6q 1160 18 % % NN cord-006870-f5w6fw6q 1160 19 ) ) -RRB- cord-006870-f5w6fw6q 1160 20 and and CC cord-006870-f5w6fw6q 1160 21 a a DT cord-006870-f5w6fw6q 1160 22 nurse nurse NN cord-006870-f5w6fw6q 1160 23 - - HYPH cord-006870-f5w6fw6q 1160 24 to to IN cord-006870-f5w6fw6q 1160 25 - - HYPH cord-006870-f5w6fw6q 1160 26 bed bed NN cord-006870-f5w6fw6q 1160 27 ratio ratio NN cord-006870-f5w6fw6q 1160 28 of of IN cord-006870-f5w6fw6q 1160 29 1:1 1:1 CD cord-006870-f5w6fw6q 1160 30 ( ( -LRB- cord-006870-f5w6fw6q 1160 31 37.6 37.6 CD cord-006870-f5w6fw6q 1160 32 % % NN cord-006870-f5w6fw6q 1160 33 ) ) -RRB- cord-006870-f5w6fw6q 1160 34 . . . cord-006870-f5w6fw6q 1161 1 And and CC cord-006870-f5w6fw6q 1161 2 respiratory respiratory JJ cord-006870-f5w6fw6q 1161 3 therapists therapist NNS cord-006870-f5w6fw6q 1161 4 , , , cord-006870-f5w6fw6q 1161 5 clinical clinical JJ cord-006870-f5w6fw6q 1161 6 dieticians dietician NNS cord-006870-f5w6fw6q 1161 7 , , , cord-006870-f5w6fw6q 1161 8 clinical clinical JJ cord-006870-f5w6fw6q 1161 9 pharmacists pharmacist NNS cord-006870-f5w6fw6q 1161 10 , , , cord-006870-f5w6fw6q 1161 11 and and CC cord-006870-f5w6fw6q 1161 12 physiotherapists physiotherapist NNS cord-006870-f5w6fw6q 1161 13 were be VBD cord-006870-f5w6fw6q 1161 14 present present JJ cord-006870-f5w6fw6q 1161 15 in in IN cord-006870-f5w6fw6q 1161 16 5.9 5.9 CD cord-006870-f5w6fw6q 1161 17 % % NN cord-006870-f5w6fw6q 1161 18 , , , cord-006870-f5w6fw6q 1161 19 32.7 32.7 CD cord-006870-f5w6fw6q 1161 20 % % NN cord-006870-f5w6fw6q 1161 21 , , , cord-006870-f5w6fw6q 1161 22 36.6 36.6 CD cord-006870-f5w6fw6q 1161 23 % % NN cord-006870-f5w6fw6q 1161 24 and and CC cord-006870-f5w6fw6q 1161 25 49.5 49.5 CD cord-006870-f5w6fw6q 1161 26 % % NN cord-006870-f5w6fw6q 1161 27 of of IN cord-006870-f5w6fw6q 1161 28 the the DT cord-006870-f5w6fw6q 1161 29 101 101 CD cord-006870-f5w6fw6q 1161 30 NCUs ncus NN cord-006870-f5w6fw6q 1161 31 . . . cord-006870-f5w6fw6q 1162 1 The the DT cord-006870-f5w6fw6q 1162 2 number number NN cord-006870-f5w6fw6q 1162 3 of of IN cord-006870-f5w6fw6q 1162 4 NCUs NCUs NNP cord-006870-f5w6fw6q 1162 5 increased increase VBD cord-006870-f5w6fw6q 1162 6 , , , cord-006870-f5w6fw6q 1162 7 the the DT cord-006870-f5w6fw6q 1162 8 availability availability NN cord-006870-f5w6fw6q 1162 9 of of IN cord-006870-f5w6fw6q 1162 10 NCU NCU NNP cord-006870-f5w6fw6q 1162 11 equipment equipment NN cord-006870-f5w6fw6q 1162 12 became become VBD cord-006870-f5w6fw6q 1162 13 more more RBR cord-006870-f5w6fw6q 1162 14 sufficient sufficient JJ cord-006870-f5w6fw6q 1162 15 , , , cord-006870-f5w6fw6q 1162 16 and and CC cord-006870-f5w6fw6q 1162 17 the the DT cord-006870-f5w6fw6q 1162 18 staffing staffing NN cord-006870-f5w6fw6q 1162 19 of of IN cord-006870-f5w6fw6q 1162 20 NCUs NCUs NNP cord-006870-f5w6fw6q 1162 21 improved improve VBN cord-006870-f5w6fw6q 1162 22 . . . cord-006870-f5w6fw6q 1163 1 However however RB cord-006870-f5w6fw6q 1163 2 , , , cord-006870-f5w6fw6q 1163 3 we -PRON- PRP cord-006870-f5w6fw6q 1163 4 should should MD cord-006870-f5w6fw6q 1163 5 pay pay VB cord-006870-f5w6fw6q 1163 6 attention attention NN cord-006870-f5w6fw6q 1163 7 to to IN cord-006870-f5w6fw6q 1163 8 the the DT cord-006870-f5w6fw6q 1163 9 management management NN cord-006870-f5w6fw6q 1163 10 of of IN cord-006870-f5w6fw6q 1163 11 specialized specialized JJ cord-006870-f5w6fw6q 1163 12 NCU NCU NNP cord-006870-f5w6fw6q 1163 13 equipment equipment NN cord-006870-f5w6fw6q 1163 14 , , , cord-006870-f5w6fw6q 1163 15 the the DT cord-006870-f5w6fw6q 1163 16 shortage shortage NN cord-006870-f5w6fw6q 1163 17 of of IN cord-006870-f5w6fw6q 1163 18 NCU NCU NNP cord-006870-f5w6fw6q 1163 19 staff staff NN cord-006870-f5w6fw6q 1163 20 , , , cord-006870-f5w6fw6q 1163 21 and and CC cord-006870-f5w6fw6q 1163 22 the the DT cord-006870-f5w6fw6q 1163 23 need need NN cord-006870-f5w6fw6q 1163 24 of of IN cord-006870-f5w6fw6q 1163 25 NCU NCU NNP cord-006870-f5w6fw6q 1163 26 training training NN cord-006870-f5w6fw6q 1163 27 . . . cord-006870-f5w6fw6q 1164 1 Automated automated JJ cord-006870-f5w6fw6q 1164 2 devices device NNS cord-006870-f5w6fw6q 1164 3 collecting collect VBG cord-006870-f5w6fw6q 1164 4 quantitative quantitative JJ cord-006870-f5w6fw6q 1164 5 measurements measurement NNS cord-006870-f5w6fw6q 1164 6 of of IN cord-006870-f5w6fw6q 1164 7 pupil pupil NN cord-006870-f5w6fw6q 1164 8 size size NN cord-006870-f5w6fw6q 1164 9 and and CC cord-006870-f5w6fw6q 1164 10 reactivity reactivity NN cord-006870-f5w6fw6q 1164 11 are be VBP cord-006870-f5w6fw6q 1164 12 increasingly increasingly RB cord-006870-f5w6fw6q 1164 13 used use VBN cord-006870-f5w6fw6q 1164 14 for for IN cord-006870-f5w6fw6q 1164 15 critically critically RB cord-006870-f5w6fw6q 1164 16 ill ill JJ cord-006870-f5w6fw6q 1164 17 patients patient NNS cord-006870-f5w6fw6q 1164 18 with with IN cord-006870-f5w6fw6q 1164 19 neurologic neurologic JJ cord-006870-f5w6fw6q 1164 20 disease disease NN cord-006870-f5w6fw6q 1164 21 . . . cord-006870-f5w6fw6q 1165 1 However however RB cord-006870-f5w6fw6q 1165 2 , , , cord-006870-f5w6fw6q 1165 3 there there EX cord-006870-f5w6fw6q 1165 4 is be VBZ cord-006870-f5w6fw6q 1165 5 limited limited JJ cord-006870-f5w6fw6q 1165 6 data datum NNS cord-006870-f5w6fw6q 1165 7 on on IN cord-006870-f5w6fw6q 1165 8 the the DT cord-006870-f5w6fw6q 1165 9 effect effect NN cord-006870-f5w6fw6q 1165 10 of of IN cord-006870-f5w6fw6q 1165 11 ambient ambient JJ cord-006870-f5w6fw6q 1165 12 light light JJ cord-006870-f5w6fw6q 1165 13 conditions condition NNS cord-006870-f5w6fw6q 1165 14 on on IN cord-006870-f5w6fw6q 1165 15 pupil pupil NN cord-006870-f5w6fw6q 1165 16 metrics metric NNS cord-006870-f5w6fw6q 1165 17 . . . cord-006870-f5w6fw6q 1166 1 To to TO cord-006870-f5w6fw6q 1166 2 address address VB cord-006870-f5w6fw6q 1166 3 this this DT cord-006870-f5w6fw6q 1166 4 issue issue NN cord-006870-f5w6fw6q 1166 5 , , , cord-006870-f5w6fw6q 1166 6 we -PRON- PRP cord-006870-f5w6fw6q 1166 7 we -PRON- PRP cord-006870-f5w6fw6q 1166 8 tested test VBD cord-006870-f5w6fw6q 1166 9 the the DT cord-006870-f5w6fw6q 1166 10 range range NN cord-006870-f5w6fw6q 1166 11 of of IN cord-006870-f5w6fw6q 1166 12 pupil pupil NN cord-006870-f5w6fw6q 1166 13 reactivity reactivity NN cord-006870-f5w6fw6q 1166 14 in in IN cord-006870-f5w6fw6q 1166 15 healthy healthy JJ cord-006870-f5w6fw6q 1166 16 volunteers volunteer NNS cord-006870-f5w6fw6q 1166 17 in in IN cord-006870-f5w6fw6q 1166 18 both both DT cord-006870-f5w6fw6q 1166 19 light light JJ cord-006870-f5w6fw6q 1166 20 and and CC cord-006870-f5w6fw6q 1166 21 dark dark JJ cord-006870-f5w6fw6q 1166 22 conditions condition NNS cord-006870-f5w6fw6q 1166 23 . . . cord-006870-f5w6fw6q 1167 1 We -PRON- PRP cord-006870-f5w6fw6q 1167 2 measured measure VBD cord-006870-f5w6fw6q 1167 3 quantitative quantitative JJ cord-006870-f5w6fw6q 1167 4 pupil pupil NN cord-006870-f5w6fw6q 1167 5 size size NN cord-006870-f5w6fw6q 1167 6 and and CC cord-006870-f5w6fw6q 1167 7 reactivity reactivity NN cord-006870-f5w6fw6q 1167 8 in in IN cord-006870-f5w6fw6q 1167 9 seven seven CD cord-006870-f5w6fw6q 1167 10 healthy healthy JJ cord-006870-f5w6fw6q 1167 11 volunteers volunteer NNS cord-006870-f5w6fw6q 1167 12 with with IN cord-006870-f5w6fw6q 1167 13 the the DT cord-006870-f5w6fw6q 1167 14 Neuroptics-200 Neuroptics-200 NNP cord-006870-f5w6fw6q 1167 15 pupillometer pupillometer NN cord-006870-f5w6fw6q 1167 16 in in IN cord-006870-f5w6fw6q 1167 17 both both CC cord-006870-f5w6fw6q 1167 18 bright bright JJ cord-006870-f5w6fw6q 1167 19 and and CC cord-006870-f5w6fw6q 1167 20 dark dark JJ cord-006870-f5w6fw6q 1167 21 ambient ambient JJ cord-006870-f5w6fw6q 1167 22 lighting lighting NN cord-006870-f5w6fw6q 1167 23 conditions condition NNS cord-006870-f5w6fw6q 1167 24 . . . cord-006870-f5w6fw6q 1168 1 Bright bright JJ cord-006870-f5w6fw6q 1168 2 conditions condition NNS cord-006870-f5w6fw6q 1168 3 were be VBD cord-006870-f5w6fw6q 1168 4 created create VBN cord-006870-f5w6fw6q 1168 5 by by IN cord-006870-f5w6fw6q 1168 6 overhead overhead JJ cord-006870-f5w6fw6q 1168 7 LED LED NNP cord-006870-f5w6fw6q 1168 8 lighting light VBG cord-006870-f5w6fw6q 1168 9 in in IN cord-006870-f5w6fw6q 1168 10 a a DT cord-006870-f5w6fw6q 1168 11 room room NN cord-006870-f5w6fw6q 1168 12 with with IN cord-006870-f5w6fw6q 1168 13 ample ample JJ cord-006870-f5w6fw6q 1168 14 natural natural JJ cord-006870-f5w6fw6q 1168 15 light light NN cord-006870-f5w6fw6q 1168 16 . . . cord-006870-f5w6fw6q 1169 1 Dark dark JJ cord-006870-f5w6fw6q 1169 2 conditions condition NNS cord-006870-f5w6fw6q 1169 3 consisted consist VBD cord-006870-f5w6fw6q 1169 4 of of IN cord-006870-f5w6fw6q 1169 5 a a DT cord-006870-f5w6fw6q 1169 6 windowless windowless JJ cord-006870-f5w6fw6q 1169 7 room room NN cord-006870-f5w6fw6q 1169 8 with with IN cord-006870-f5w6fw6q 1169 9 no no DT cord-006870-f5w6fw6q 1169 10 overhead overhead JJ cord-006870-f5w6fw6q 1169 11 light light JJ cord-006870-f5w6fw6q 1169 12 source source NN cord-006870-f5w6fw6q 1169 13 . . . cord-006870-f5w6fw6q 1170 1 The the DT cord-006870-f5w6fw6q 1170 2 primary primary JJ cord-006870-f5w6fw6q 1170 3 outcome outcome NN cord-006870-f5w6fw6q 1170 4 was be VBD cord-006870-f5w6fw6q 1170 5 the the DT cord-006870-f5w6fw6q 1170 6 Neurologic Neurologic NNP cord-006870-f5w6fw6q 1170 7 Pupil Pupil NNP cord-006870-f5w6fw6q 1170 8 Index Index NNP cord-006870-f5w6fw6q 1170 9 ( ( -LRB- cord-006870-f5w6fw6q 1170 10 NPi NPi NNP cord-006870-f5w6fw6q 1170 11 ) ) -RRB- cord-006870-f5w6fw6q 1170 12 , , , cord-006870-f5w6fw6q 1170 13 a a DT cord-006870-f5w6fw6q 1170 14 composite composite JJ cord-006870-f5w6fw6q 1170 15 metric metric NN cord-006870-f5w6fw6q 1170 16 ranging range VBG cord-006870-f5w6fw6q 1170 17 from from IN cord-006870-f5w6fw6q 1170 18 0 0 CD cord-006870-f5w6fw6q 1170 19 - - SYM cord-006870-f5w6fw6q 1170 20 5 5 CD cord-006870-f5w6fw6q 1170 21 in in IN cord-006870-f5w6fw6q 1170 22 which which WDT cord-006870-f5w6fw6q 1171 1 > > XX cord-006870-f5w6fw6q 1172 1 3 3 CD cord-006870-f5w6fw6q 1172 2 is be VBZ cord-006870-f5w6fw6q 1172 3 considered consider VBN cord-006870-f5w6fw6q 1172 4 normal normal JJ cord-006870-f5w6fw6q 1172 5 . . . cord-006870-f5w6fw6q 1173 1 Secondary secondary JJ cord-006870-f5w6fw6q 1173 2 outcomes outcome NNS cord-006870-f5w6fw6q 1173 3 included include VBD cord-006870-f5w6fw6q 1173 4 resting rest VBG cord-006870-f5w6fw6q 1173 5 and and CC cord-006870-f5w6fw6q 1173 6 constricted constricted JJ cord-006870-f5w6fw6q 1173 7 pupil pupil NN cord-006870-f5w6fw6q 1173 8 size size NN cord-006870-f5w6fw6q 1173 9 , , , cord-006870-f5w6fw6q 1173 10 change change NN cord-006870-f5w6fw6q 1173 11 in in IN cord-006870-f5w6fw6q 1173 12 pupil pupil NN cord-006870-f5w6fw6q 1173 13 size size NN cord-006870-f5w6fw6q 1173 14 , , , cord-006870-f5w6fw6q 1173 15 constriction constriction NN cord-006870-f5w6fw6q 1173 16 velocity velocity NN cord-006870-f5w6fw6q 1173 17 , , , cord-006870-f5w6fw6q 1173 18 dilation dilation NN cord-006870-f5w6fw6q 1173 19 velocity velocity NN cord-006870-f5w6fw6q 1173 20 and and CC cord-006870-f5w6fw6q 1173 21 latency latency NN cord-006870-f5w6fw6q 1173 22 . . . cord-006870-f5w6fw6q 1174 1 Results result NNS cord-006870-f5w6fw6q 1174 2 were be VBD cord-006870-f5w6fw6q 1174 3 analyzed analyze VBN cord-006870-f5w6fw6q 1174 4 with with IN cord-006870-f5w6fw6q 1174 5 multi multi JJ cord-006870-f5w6fw6q 1174 6 - - JJ cord-006870-f5w6fw6q 1174 7 level level JJ cord-006870-f5w6fw6q 1174 8 linear linear JJ cord-006870-f5w6fw6q 1174 9 regression regression NN cord-006870-f5w6fw6q 1174 10 to to TO cord-006870-f5w6fw6q 1174 11 account account VB cord-006870-f5w6fw6q 1174 12 for for IN cord-006870-f5w6fw6q 1174 13 both both DT cord-006870-f5w6fw6q 1174 14 inter inter JJ cord-006870-f5w6fw6q 1174 15 and and CC cord-006870-f5w6fw6q 1174 16 intra intra JJ cord-006870-f5w6fw6q 1174 17 - - JJ cord-006870-f5w6fw6q 1174 18 subject subject JJ cord-006870-f5w6fw6q 1174 19 variability variability NN cord-006870-f5w6fw6q 1174 20 . . . cord-006870-f5w6fw6q 1175 1 Seven seven CD cord-006870-f5w6fw6q 1175 2 subjects subject NNS cord-006870-f5w6fw6q 1175 3 underwent undergo VBD cord-006870-f5w6fw6q 1175 4 ten ten CD cord-006870-f5w6fw6q 1175 5 pupil pupil NN cord-006870-f5w6fw6q 1175 6 - - HYPH cord-006870-f5w6fw6q 1175 7 readings reading NNS cord-006870-f5w6fw6q 1175 8 in in IN cord-006870-f5w6fw6q 1175 9 bright bright JJ cord-006870-f5w6fw6q 1175 10 and and CC cord-006870-f5w6fw6q 1175 11 dark dark JJ cord-006870-f5w6fw6q 1175 12 conditions condition NNS cord-006870-f5w6fw6q 1175 13 , , , cord-006870-f5w6fw6q 1175 14 yielding yield VBG cord-006870-f5w6fw6q 1175 15 140 140 CD cord-006870-f5w6fw6q 1175 16 total total JJ cord-006870-f5w6fw6q 1175 17 measurements measurement NNS cord-006870-f5w6fw6q 1175 18 . . . cord-006870-f5w6fw6q 1176 1 Mean mean JJ cord-006870-f5w6fw6q 1176 2 resting rest VBG cord-006870-f5w6fw6q 1176 3 pupil pupil NN cord-006870-f5w6fw6q 1176 4 sizes size NNS cord-006870-f5w6fw6q 1176 5 were be VBD cord-006870-f5w6fw6q 1176 6 3.56 3.56 CD cord-006870-f5w6fw6q 1176 7 v. v. CC cord-006870-f5w6fw6q 1176 8 [ [ -LRB- cord-006870-f5w6fw6q 1176 9 13.8 13.8 CD cord-006870-f5w6fw6q 1176 10 - - HYPH cord-006870-f5w6fw6q 1176 11 16.4 16.4 CD cord-006870-f5w6fw6q 1176 12 ] ] -RRB- cord-006870-f5w6fw6q 1176 13 , , , cord-006870-f5w6fw6q 1176 14 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1176 15 ) ) -RRB- cord-006870-f5w6fw6q 1176 16 . . . cord-006870-f5w6fw6q 1177 1 All all DT cord-006870-f5w6fw6q 1177 2 additional additional JJ cord-006870-f5w6fw6q 1177 3 secondary secondary JJ cord-006870-f5w6fw6q 1177 4 outcomes outcome NNS cord-006870-f5w6fw6q 1177 5 except except IN cord-006870-f5w6fw6q 1177 6 latency latency NNP cord-006870-f5w6fw6q 1177 7 were be VBD cord-006870-f5w6fw6q 1177 8 also also RB cord-006870-f5w6fw6q 1177 9 significantly significantly RB cord-006870-f5w6fw6q 1177 10 different different JJ cord-006870-f5w6fw6q 1177 11 between between IN cord-006870-f5w6fw6q 1177 12 conditions condition NNS cord-006870-f5w6fw6q 1177 13 . . . cord-006870-f5w6fw6q 1178 1 We -PRON- PRP cord-006870-f5w6fw6q 1178 2 found find VBD cord-006870-f5w6fw6q 1178 3 that that IN cord-006870-f5w6fw6q 1178 4 ambient ambient JJ cord-006870-f5w6fw6q 1178 5 light light JJ cord-006870-f5w6fw6q 1178 6 levels level NNS cord-006870-f5w6fw6q 1178 7 impact impact NN cord-006870-f5w6fw6q 1178 8 pupil pupil NN cord-006870-f5w6fw6q 1178 9 parameters parameter NNS cord-006870-f5w6fw6q 1178 10 in in IN cord-006870-f5w6fw6q 1178 11 healthy healthy JJ cord-006870-f5w6fw6q 1178 12 subjects subject NNS cord-006870-f5w6fw6q 1178 13 . . . cord-006870-f5w6fw6q 1179 1 However however RB cord-006870-f5w6fw6q 1179 2 , , , cord-006870-f5w6fw6q 1179 3 changes change NNS cord-006870-f5w6fw6q 1179 4 in in IN cord-006870-f5w6fw6q 1179 5 NPi NPi NNS cord-006870-f5w6fw6q 1179 6 are be VBP cord-006870-f5w6fw6q 1179 7 small small JJ cord-006870-f5w6fw6q 1179 8 and and CC cord-006870-f5w6fw6q 1179 9 more more RBR cord-006870-f5w6fw6q 1179 10 consistent consistent JJ cord-006870-f5w6fw6q 1179 11 in in IN cord-006870-f5w6fw6q 1179 12 varying vary VBG cord-006870-f5w6fw6q 1179 13 lighting lighting NN cord-006870-f5w6fw6q 1179 14 conditions condition NNS cord-006870-f5w6fw6q 1179 15 than than IN cord-006870-f5w6fw6q 1179 16 other other JJ cord-006870-f5w6fw6q 1179 17 metrics metric NNS cord-006870-f5w6fw6q 1179 18 . . . cord-006870-f5w6fw6q 1180 1 Further further JJ cord-006870-f5w6fw6q 1180 2 testing testing NN cord-006870-f5w6fw6q 1180 3 of of IN cord-006870-f5w6fw6q 1180 4 patients patient NNS cord-006870-f5w6fw6q 1180 5 with with IN cord-006870-f5w6fw6q 1180 6 poor poor JJ cord-006870-f5w6fw6q 1180 7 pupil pupil NN cord-006870-f5w6fw6q 1180 8 reactivity reactivity NN cord-006870-f5w6fw6q 1180 9 is be VBZ cord-006870-f5w6fw6q 1180 10 necessary necessary JJ cord-006870-f5w6fw6q 1180 11 to to TO cord-006870-f5w6fw6q 1180 12 determine determine VB cord-006870-f5w6fw6q 1180 13 if if IN cord-006870-f5w6fw6q 1180 14 ambient ambient JJ cord-006870-f5w6fw6q 1180 15 light light JJ cord-006870-f5w6fw6q 1180 16 conditions condition NNS cord-006870-f5w6fw6q 1180 17 could could MD cord-006870-f5w6fw6q 1180 18 influence influence VB cord-006870-f5w6fw6q 1180 19 clinical clinical JJ cord-006870-f5w6fw6q 1180 20 assessment assessment NN cord-006870-f5w6fw6q 1180 21 in in IN cord-006870-f5w6fw6q 1180 22 the the DT cord-006870-f5w6fw6q 1180 23 critically critically RB cord-006870-f5w6fw6q 1180 24 ill ill JJ cord-006870-f5w6fw6q 1180 25 . . . cord-006870-f5w6fw6q 1181 1 Practitioners practitioner NNS cord-006870-f5w6fw6q 1181 2 should should MD cord-006870-f5w6fw6q 1181 3 standardize standardize VB cord-006870-f5w6fw6q 1181 4 lighting lighting NN cord-006870-f5w6fw6q 1181 5 conditions condition NNS cord-006870-f5w6fw6q 1181 6 to to TO cord-006870-f5w6fw6q 1181 7 maximize maximize VB cord-006870-f5w6fw6q 1181 8 the the DT cord-006870-f5w6fw6q 1181 9 reliability reliability NN cord-006870-f5w6fw6q 1181 10 of of IN cord-006870-f5w6fw6q 1181 11 their -PRON- PRP$ cord-006870-f5w6fw6q 1181 12 measurements measurement NNS cord-006870-f5w6fw6q 1181 13 . . . cord-006870-f5w6fw6q 1182 1 Neural neural JJ cord-006870-f5w6fw6q 1182 2 stem stem NN cord-006870-f5w6fw6q 1182 3 cells cell NNS cord-006870-f5w6fw6q 1182 4 ( ( -LRB- cord-006870-f5w6fw6q 1182 5 NSCs nscs NN cord-006870-f5w6fw6q 1182 6 ) ) -RRB- cord-006870-f5w6fw6q 1182 7 are be VBP cord-006870-f5w6fw6q 1182 8 known know VBN cord-006870-f5w6fw6q 1182 9 to to TO cord-006870-f5w6fw6q 1182 10 have have VB cord-006870-f5w6fw6q 1182 11 anti anti JJ cord-006870-f5w6fw6q 1182 12 - - JJ cord-006870-f5w6fw6q 1182 13 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1182 14 effect effect NN cord-006870-f5w6fw6q 1182 15 in in IN cord-006870-f5w6fw6q 1182 16 strokes stroke NNS cord-006870-f5w6fw6q 1182 17 in in IN cord-006870-f5w6fw6q 1182 18 previous previous JJ cord-006870-f5w6fw6q 1182 19 studies study NNS cord-006870-f5w6fw6q 1182 20 . . . cord-006870-f5w6fw6q 1183 1 However however RB cord-006870-f5w6fw6q 1183 2 , , , cord-006870-f5w6fw6q 1183 3 the the DT cord-006870-f5w6fw6q 1183 4 mechanism mechanism NN cord-006870-f5w6fw6q 1183 5 of of IN cord-006870-f5w6fw6q 1183 6 anti anti JJ cord-006870-f5w6fw6q 1183 7 - - JJ cord-006870-f5w6fw6q 1183 8 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1183 9 effect effect NN cord-006870-f5w6fw6q 1183 10 in in IN cord-006870-f5w6fw6q 1183 11 direct direct JJ cord-006870-f5w6fw6q 1183 12 co co NN cord-006870-f5w6fw6q 1183 13 - - NN cord-006870-f5w6fw6q 1183 14 culture culture NN cord-006870-f5w6fw6q 1183 15 with with IN cord-006870-f5w6fw6q 1183 16 NSCs nsc NNS cord-006870-f5w6fw6q 1183 17 in in IN cord-006870-f5w6fw6q 1183 18 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1183 19 stroke stroke NN cord-006870-f5w6fw6q 1183 20 remains remain VBZ cord-006870-f5w6fw6q 1183 21 unclear unclear JJ cord-006870-f5w6fw6q 1183 22 . . . cord-006870-f5w6fw6q 1184 1 The the DT cord-006870-f5w6fw6q 1184 2 aim aim NN cord-006870-f5w6fw6q 1184 3 of of IN cord-006870-f5w6fw6q 1184 4 this this DT cord-006870-f5w6fw6q 1184 5 study study NN cord-006870-f5w6fw6q 1184 6 was be VBD cord-006870-f5w6fw6q 1184 7 to to TO cord-006870-f5w6fw6q 1184 8 investigate investigate VB cord-006870-f5w6fw6q 1184 9 whether whether IN cord-006870-f5w6fw6q 1184 10 direct direct JJ cord-006870-f5w6fw6q 1184 11 co co NN cord-006870-f5w6fw6q 1184 12 - - NN cord-006870-f5w6fw6q 1184 13 culture culture NN cord-006870-f5w6fw6q 1184 14 with with IN cord-006870-f5w6fw6q 1184 15 NSCs nscs NN cord-006870-f5w6fw6q 1184 16 modulates modulate VBZ cord-006870-f5w6fw6q 1184 17 hemolysate hemolysate RB cord-006870-f5w6fw6q 1184 18 - - HYPH cord-006870-f5w6fw6q 1184 19 induced induce VBN cord-006870-f5w6fw6q 1184 20 inflammation inflammation NN cord-006870-f5w6fw6q 1184 21 in in IN cord-006870-f5w6fw6q 1184 22 Raw Raw NNP cord-006870-f5w6fw6q 1184 23 264.7 264.7 CD cord-006870-f5w6fw6q 1184 24 cells cell NNS cord-006870-f5w6fw6q 1184 25 . . . cord-006870-f5w6fw6q 1185 1 We -PRON- PRP cord-006870-f5w6fw6q 1185 2 stimulated stimulate VBD cord-006870-f5w6fw6q 1185 3 Raw Raw NNP cord-006870-f5w6fw6q 1185 4 264.7 264.7 CD cord-006870-f5w6fw6q 1185 5 cells cell NNS cord-006870-f5w6fw6q 1185 6 with with IN cord-006870-f5w6fw6q 1185 7 hemolysate hemolysate NN cord-006870-f5w6fw6q 1185 8 to to TO cord-006870-f5w6fw6q 1185 9 induce induce VB cord-006870-f5w6fw6q 1185 10 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1185 11 inflammation inflammation NN cord-006870-f5w6fw6q 1185 12 in in IN cord-006870-f5w6fw6q 1185 13 vitro vitro FW cord-006870-f5w6fw6q 1185 14 . . . cord-006870-f5w6fw6q 1186 1 Hemolysate Hemolysate NNP cord-006870-f5w6fw6q 1186 2 - - HYPH cord-006870-f5w6fw6q 1186 3 activated activate VBN cord-006870-f5w6fw6q 1186 4 Raw Raw NNP cord-006870-f5w6fw6q 1186 5 264.7 264.7 CD cord-006870-f5w6fw6q 1186 6 cells cell NNS cord-006870-f5w6fw6q 1186 7 were be VBD cord-006870-f5w6fw6q 1186 8 co co JJ cord-006870-f5w6fw6q 1186 9 - - JJ cord-006870-f5w6fw6q 1186 10 cultured cultured JJ cord-006870-f5w6fw6q 1186 11 with with IN cord-006870-f5w6fw6q 1186 12 HB1.F3 HB1.F3 NNP cord-006870-f5w6fw6q 1187 1 directly directly RB cord-006870-f5w6fw6q 1187 2 for for IN cord-006870-f5w6fw6q 1187 3 4 4 CD cord-006870-f5w6fw6q 1187 4 hours hour NNS cord-006870-f5w6fw6q 1187 5 . . . cord-006870-f5w6fw6q 1188 1 Following follow VBG cord-006870-f5w6fw6q 1188 2 direct direct JJ cord-006870-f5w6fw6q 1188 3 co co NN cord-006870-f5w6fw6q 1188 4 - - NN cord-006870-f5w6fw6q 1188 5 culture culture NN cord-006870-f5w6fw6q 1188 6 , , , cord-006870-f5w6fw6q 1188 7 the the DT cord-006870-f5w6fw6q 1188 8 production production NN cord-006870-f5w6fw6q 1188 9 of of IN cord-006870-f5w6fw6q 1188 10 cycloxygenase-2 cycloxygenase-2 NNP cord-006870-f5w6fw6q 1188 11 ( ( -LRB- cord-006870-f5w6fw6q 1188 12 COX-2 COX-2 NNP cord-006870-f5w6fw6q 1188 13 ) ) -RRB- cord-006870-f5w6fw6q 1188 14 , , , cord-006870-f5w6fw6q 1188 15 Interleukin interleukin NN cord-006870-f5w6fw6q 1188 16 - - HYPH cord-006870-f5w6fw6q 1188 17 signal signal NN cord-006870-f5w6fw6q 1188 18 regulated regulate VBN cord-006870-f5w6fw6q 1188 19 kinase kinase NN cord-006870-f5w6fw6q 1188 20 ( ( -LRB- cord-006870-f5w6fw6q 1188 21 ERK ERK NNP cord-006870-f5w6fw6q 1188 22 ) ) -RRB- cord-006870-f5w6fw6q 1188 23 were be VBD cord-006870-f5w6fw6q 1188 24 assessed assess VBN cord-006870-f5w6fw6q 1188 25 by by IN cord-006870-f5w6fw6q 1188 26 western western JJ cord-006870-f5w6fw6q 1188 27 blotting blotting NN cord-006870-f5w6fw6q 1188 28 , , , cord-006870-f5w6fw6q 1188 29 and and CC cord-006870-f5w6fw6q 1188 30 tumor tumor NN cord-006870-f5w6fw6q 1188 31 necrosis necrosis NN cord-006870-f5w6fw6q 1188 32 factor factor NN cord-006870-f5w6fw6q 1188 33 ( ( -LRB- cord-006870-f5w6fw6q 1188 34 TNFevaluated tnfevaluate VBN cord-006870-f5w6fw6q 1188 35 by by IN cord-006870-f5w6fw6q 1188 36 enzyme enzyme NN cord-006870-f5w6fw6q 1188 37 - - HYPH cord-006870-f5w6fw6q 1188 38 linked link VBN cord-006870-f5w6fw6q 1188 39 immunosorbent immunosorbent JJ cord-006870-f5w6fw6q 1188 40 assay assay NN cord-006870-f5w6fw6q 1188 41 ( ( -LRB- cord-006870-f5w6fw6q 1188 42 ELISA ELISA NNP cord-006870-f5w6fw6q 1188 43 ) ) -RRB- cord-006870-f5w6fw6q 1188 44 . . . cord-006870-f5w6fw6q 1189 1 Hemolysate Hemolysate NNP cord-006870-f5w6fw6q 1189 2 generates generate VBZ cord-006870-f5w6fw6q 1189 3 an an DT cord-006870-f5w6fw6q 1189 4 activation activation NN cord-006870-f5w6fw6q 1189 5 of of IN cord-006870-f5w6fw6q 1189 6 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1189 7 response response NN cord-006870-f5w6fw6q 1189 8 in in IN cord-006870-f5w6fw6q 1189 9 Raw Raw NNP cord-006870-f5w6fw6q 1189 10 264.7 264.7 CD cord-006870-f5w6fw6q 1189 11 cells cell NNS cord-006870-f5w6fw6q 1189 12 . . . cord-006870-f5w6fw6q 1190 1 Direct direct JJ cord-006870-f5w6fw6q 1190 2 co co NN cord-006870-f5w6fw6q 1190 3 - - NN cord-006870-f5w6fw6q 1190 4 culture culture NN cord-006870-f5w6fw6q 1190 5 with with IN cord-006870-f5w6fw6q 1190 6 HB1.F3 HB1.F3 NNP cord-006870-f5w6fw6q 1190 7 significantly significantly RB cord-006870-f5w6fw6q 1190 8 suppressed suppress VBD cord-006870-f5w6fw6q 1190 9 the the DT cord-006870-f5w6fw6q 1190 10 phosphorylation phosphorylation NN cord-006870-f5w6fw6q 1190 11 of of IN cord-006870-f5w6fw6q 1190 12 ERK ERK NNP cord-006870-f5w6fw6q 1190 13 1/2 1/2 CD cord-006870-f5w6fw6q 1190 14 in in IN cord-006870-f5w6fw6q 1190 15 hemolysate hemolysate NN cord-006870-f5w6fw6q 1190 16 - - HYPH cord-006870-f5w6fw6q 1190 17 activated activate VBN cord-006870-f5w6fw6q 1190 18 Raw Raw NNP cord-006870-f5w6fw6q 1190 19 264.7 264.7 CD cord-006870-f5w6fw6q 1190 20 cells cell NNS cord-006870-f5w6fw6q 1190 21 . . . cord-006870-f5w6fw6q 1191 1 The the DT cord-006870-f5w6fw6q 1191 2 expression expression NN cord-006870-f5w6fw6q 1191 3 of of IN cord-006870-f5w6fw6q 1191 4 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1191 5 mediators mediator NNS cord-006870-f5w6fw6q 1191 6 such such JJ cord-006870-f5w6fw6q 1191 7 as as IN cord-006870-f5w6fw6q 1191 8 COX-2 COX-2 NNP cord-006870-f5w6fw6q 1191 9 , , , cord-006870-f5w6fw6q 1191 10 IL IL NNP cord-006870-f5w6fw6q 1191 11 - - : cord-006870-f5w6fw6q 1191 12 by by IN cord-006870-f5w6fw6q 1191 13 direct direct JJ cord-006870-f5w6fw6q 1191 14 co co NN cord-006870-f5w6fw6q 1191 15 - - NN cord-006870-f5w6fw6q 1191 16 culture culture NN cord-006870-f5w6fw6q 1191 17 with with IN cord-006870-f5w6fw6q 1191 18 HB1 HB1 NNP cord-006870-f5w6fw6q 1191 19 . . . cord-006870-f5w6fw6q 1192 1 F3 f3 NN cord-006870-f5w6fw6q 1192 2 cell cell NN cord-006870-f5w6fw6q 1192 3 . . . cord-006870-f5w6fw6q 1193 1 In in IN cord-006870-f5w6fw6q 1193 2 addition addition NN cord-006870-f5w6fw6q 1193 3 , , , cord-006870-f5w6fw6q 1193 4 the the DT cord-006870-f5w6fw6q 1193 5 expression expression NN cord-006870-f5w6fw6q 1193 6 of of IN cord-006870-f5w6fw6q 1193 7 COX-2 COX-2 NNP cord-006870-f5w6fw6q 1193 8 , , , cord-006870-f5w6fw6q 1193 9 IL IL NNP cord-006870-f5w6fw6q 1193 10 - - HYPH cord-006870-f5w6fw6q 1193 11 attenuated attenuate VBN cord-006870-f5w6fw6q 1193 12 by by IN cord-006870-f5w6fw6q 1193 13 ERK ERK NNP cord-006870-f5w6fw6q 1193 14 inhibitor inhibitor NN cord-006870-f5w6fw6q 1193 15 ( ( -LRB- cord-006870-f5w6fw6q 1193 16 U0126 U0126 NNP cord-006870-f5w6fw6q 1193 17 ) ) -RRB- cord-006870-f5w6fw6q 1193 18 . . . cord-006870-f5w6fw6q 1194 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1194 2 results result NNS cord-006870-f5w6fw6q 1194 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 1194 4 that that IN cord-006870-f5w6fw6q 1194 5 direct direct JJ cord-006870-f5w6fw6q 1194 6 co co NN cord-006870-f5w6fw6q 1194 7 - - NN cord-006870-f5w6fw6q 1194 8 culture culture NN cord-006870-f5w6fw6q 1194 9 with with IN cord-006870-f5w6fw6q 1194 10 HB1.F3 HB1.F3 NNP cord-006870-f5w6fw6q 1194 11 cells cell NNS cord-006870-f5w6fw6q 1194 12 reduced reduce VBD cord-006870-f5w6fw6q 1194 13 the the DT cord-006870-f5w6fw6q 1194 14 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1194 15 responses response NNS cord-006870-f5w6fw6q 1194 16 in in IN cord-006870-f5w6fw6q 1194 17 hemolysate hemolysate NN cord-006870-f5w6fw6q 1194 18 - - HYPH cord-006870-f5w6fw6q 1194 19 activated activate VBN cord-006870-f5w6fw6q 1194 20 inflammation inflammation NN cord-006870-f5w6fw6q 1194 21 via via IN cord-006870-f5w6fw6q 1194 22 suppressing suppress VBG cord-006870-f5w6fw6q 1194 23 ERK1/2 ERK1/2 NNP cord-006870-f5w6fw6q 1194 24 pathway pathway NN cord-006870-f5w6fw6q 1194 25 . . . cord-006870-f5w6fw6q 1195 1 This this DT cord-006870-f5w6fw6q 1195 2 suggests suggest VBZ cord-006870-f5w6fw6q 1195 3 that that IN cord-006870-f5w6fw6q 1195 4 NSCs nscs NN cord-006870-f5w6fw6q 1195 5 treatment treatment NN cord-006870-f5w6fw6q 1195 6 can can MD cord-006870-f5w6fw6q 1195 7 suppress suppress VB cord-006870-f5w6fw6q 1195 8 the the DT cord-006870-f5w6fw6q 1195 9 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1195 10 response response NN cord-006870-f5w6fw6q 1195 11 in in IN cord-006870-f5w6fw6q 1195 12 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1195 13 stroke stroke NN cord-006870-f5w6fw6q 1195 14 . . . cord-006870-f5w6fw6q 1196 1 No no DT cord-006870-f5w6fw6q 1196 2 pharmacological pharmacological JJ cord-006870-f5w6fw6q 1196 3 intervention intervention NN cord-006870-f5w6fw6q 1196 4 improves improve VBZ cord-006870-f5w6fw6q 1196 5 outcomes outcome NNS cord-006870-f5w6fw6q 1196 6 after after IN cord-006870-f5w6fw6q 1196 7 primary primary JJ cord-006870-f5w6fw6q 1196 8 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1196 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1196 10 ( ( -LRB- cord-006870-f5w6fw6q 1196 11 ICH ICH NNP cord-006870-f5w6fw6q 1196 12 ) ) -RRB- cord-006870-f5w6fw6q 1196 13 . . . cord-006870-f5w6fw6q 1197 1 We -PRON- PRP cord-006870-f5w6fw6q 1197 2 developed develop VBD cord-006870-f5w6fw6q 1197 3 a a DT cord-006870-f5w6fw6q 1197 4 novel novel JJ cord-006870-f5w6fw6q 1197 5 therapeutic therapeutic JJ cord-006870-f5w6fw6q 1197 6 approach approach NN cord-006870-f5w6fw6q 1197 7 based base VBN cord-006870-f5w6fw6q 1197 8 on on IN cord-006870-f5w6fw6q 1197 9 known know VBN cord-006870-f5w6fw6q 1197 10 biological biological JJ cord-006870-f5w6fw6q 1197 11 function function NN cord-006870-f5w6fw6q 1197 12 of of IN cord-006870-f5w6fw6q 1197 13 endogenous endogenous JJ cord-006870-f5w6fw6q 1197 14 apolipoprotein apolipoprotein NN cord-006870-f5w6fw6q 1197 15 E e NN cord-006870-f5w6fw6q 1197 16 ( ( -LRB- cord-006870-f5w6fw6q 1197 17 apoE apoE NNS cord-006870-f5w6fw6q 1197 18 ) ) -RRB- cord-006870-f5w6fw6q 1197 19 . . . cord-006870-f5w6fw6q 1198 1 ApoE ApoE NNP cord-006870-f5w6fw6q 1198 2 is be VBZ cord-006870-f5w6fw6q 1198 3 a a DT cord-006870-f5w6fw6q 1198 4 key key JJ cord-006870-f5w6fw6q 1198 5 mediator mediator NN cord-006870-f5w6fw6q 1198 6 of of IN cord-006870-f5w6fw6q 1198 7 neuroinflammatory neuroinflammatory NNP cord-006870-f5w6fw6q 1198 8 responses response NNS cord-006870-f5w6fw6q 1198 9 and and CC cord-006870-f5w6fw6q 1198 10 modifies modify VBZ cord-006870-f5w6fw6q 1198 11 recovery recovery NN cord-006870-f5w6fw6q 1198 12 from from IN cord-006870-f5w6fw6q 1198 13 a a DT cord-006870-f5w6fw6q 1198 14 variety variety NN cord-006870-f5w6fw6q 1198 15 of of IN cord-006870-f5w6fw6q 1198 16 acute acute JJ cord-006870-f5w6fw6q 1198 17 and and CC cord-006870-f5w6fw6q 1198 18 chronic chronic JJ cord-006870-f5w6fw6q 1198 19 brain brain NN cord-006870-f5w6fw6q 1198 20 injuries injury NNS cord-006870-f5w6fw6q 1198 21 . . . cord-006870-f5w6fw6q 1199 1 Unfortunately unfortunately RB cord-006870-f5w6fw6q 1199 2 , , , cord-006870-f5w6fw6q 1199 3 intact intact JJ cord-006870-f5w6fw6q 1199 4 apoE apoe CC cord-006870-f5w6fw6q 1199 5 holoprotein holoprotein NNP cord-006870-f5w6fw6q 1199 6 does do VBZ cord-006870-f5w6fw6q 1199 7 not not RB cord-006870-f5w6fw6q 1199 8 cross cross VB cord-006870-f5w6fw6q 1199 9 the the DT cord-006870-f5w6fw6q 1199 10 blood blood NN cord-006870-f5w6fw6q 1199 11 brain brain NN cord-006870-f5w6fw6q 1199 12 barrier barrier NN cord-006870-f5w6fw6q 1199 13 ( ( -LRB- cord-006870-f5w6fw6q 1199 14 BBB BBB NNP cord-006870-f5w6fw6q 1199 15 ) ) -RRB- cord-006870-f5w6fw6q 1199 16 and and CC cord-006870-f5w6fw6q 1199 17 can can MD cord-006870-f5w6fw6q 1199 18 not not RB cord-006870-f5w6fw6q 1199 19 be be VB cord-006870-f5w6fw6q 1199 20 administered administer VBN cord-006870-f5w6fw6q 1199 21 as as IN cord-006870-f5w6fw6q 1199 22 a a DT cord-006870-f5w6fw6q 1199 23 neurotherapeutic neurotherapeutic NN cord-006870-f5w6fw6q 1199 24 . . . cord-006870-f5w6fw6q 1200 1 We -PRON- PRP cord-006870-f5w6fw6q 1200 2 created create VBD cord-006870-f5w6fw6q 1200 3 apoEmimetic apoemimetic JJ cord-006870-f5w6fw6q 1200 4 peptides peptide NNS cord-006870-f5w6fw6q 1200 5 that that WDT cord-006870-f5w6fw6q 1200 6 cross cross VBP cord-006870-f5w6fw6q 1200 7 the the DT cord-006870-f5w6fw6q 1200 8 BBB BBB NNP cord-006870-f5w6fw6q 1200 9 and and CC cord-006870-f5w6fw6q 1200 10 down down RB cord-006870-f5w6fw6q 1200 11 - - HYPH cord-006870-f5w6fw6q 1200 12 regulate regulate VB cord-006870-f5w6fw6q 1200 13 neuroinflammatory neuroinflammatory JJ cord-006870-f5w6fw6q 1200 14 responses response NNS cord-006870-f5w6fw6q 1200 15 in in IN cord-006870-f5w6fw6q 1200 16 vitro vitro FW cord-006870-f5w6fw6q 1200 17 and and CC cord-006870-f5w6fw6q 1200 18 in in IN cord-006870-f5w6fw6q 1200 19 vivo vivo NNP cord-006870-f5w6fw6q 1200 20 . . . cord-006870-f5w6fw6q 1201 1 CN-105 CN-105 NNP cord-006870-f5w6fw6q 1201 2 , , , cord-006870-f5w6fw6q 1201 3 our -PRON- PRP$ cord-006870-f5w6fw6q 1201 4 lead lead NN cord-006870-f5w6fw6q 1201 5 candidate candidate NN cord-006870-f5w6fw6q 1201 6 , , , cord-006870-f5w6fw6q 1201 7 is be VBZ cord-006870-f5w6fw6q 1201 8 a a DT cord-006870-f5w6fw6q 1201 9 5-amino 5-amino CD cord-006870-f5w6fw6q 1201 10 acid acid NN cord-006870-f5w6fw6q 1201 11 apoE apoE NNS cord-006870-f5w6fw6q 1201 12 - - HYPH cord-006870-f5w6fw6q 1201 13 mimetic mimetic NN cord-006870-f5w6fw6q 1201 14 peptide peptide NN cord-006870-f5w6fw6q 1201 15 derived derive VBN cord-006870-f5w6fw6q 1201 16 from from IN cord-006870-f5w6fw6q 1201 17 apoE apoE NNPS cord-006870-f5w6fw6q 1201 18 's 's POS cord-006870-f5w6fw6q 1201 19 receptorregion receptorregion NN cord-006870-f5w6fw6q 1201 20 . . . cord-006870-f5w6fw6q 1202 1 CN-105 CN-105 NNP cord-006870-f5w6fw6q 1202 2 retains retain VBZ cord-006870-f5w6fw6q 1202 3 anti anti JJ cord-006870-f5w6fw6q 1202 4 - - JJ cord-006870-f5w6fw6q 1202 5 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1202 6 and and CC cord-006870-f5w6fw6q 1202 7 neuroprotective neuroprotective JJ cord-006870-f5w6fw6q 1202 8 effects effect NNS cord-006870-f5w6fw6q 1202 9 of of IN cord-006870-f5w6fw6q 1202 10 intact intact JJ cord-006870-f5w6fw6q 1202 11 apoE apoE NNS cord-006870-f5w6fw6q 1202 12 , , , cord-006870-f5w6fw6q 1202 13 was be VBD cord-006870-f5w6fw6q 1202 14 well well RB cord-006870-f5w6fw6q 1202 15 - - HYPH cord-006870-f5w6fw6q 1202 16 tolerated tolerate VBN cord-006870-f5w6fw6q 1202 17 in in IN cord-006870-f5w6fw6q 1202 18 preclinical preclinical JJ cord-006870-f5w6fw6q 1202 19 studies study NNS cord-006870-f5w6fw6q 1202 20 , , , cord-006870-f5w6fw6q 1202 21 readily readily RB cord-006870-f5w6fw6q 1202 22 crosses cross VBZ cord-006870-f5w6fw6q 1202 23 the the DT cord-006870-f5w6fw6q 1202 24 BBB BBB NNP cord-006870-f5w6fw6q 1202 25 , , , cord-006870-f5w6fw6q 1202 26 and and CC cord-006870-f5w6fw6q 1202 27 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 1202 28 excellent excellent JJ cord-006870-f5w6fw6q 1202 29 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 1202 30 , , , cord-006870-f5w6fw6q 1202 31 safety safety NN cord-006870-f5w6fw6q 1202 32 , , , cord-006870-f5w6fw6q 1202 33 and and CC cord-006870-f5w6fw6q 1202 34 tolerability tolerability NN cord-006870-f5w6fw6q 1202 35 profiles profile NNS cord-006870-f5w6fw6q 1202 36 in in IN cord-006870-f5w6fw6q 1202 37 Phase phase NN cord-006870-f5w6fw6q 1202 38 1 1 CD cord-006870-f5w6fw6q 1202 39 studies study NNS cord-006870-f5w6fw6q 1202 40 . . . cord-006870-f5w6fw6q 1203 1 This this DT cord-006870-f5w6fw6q 1203 2 is be VBZ cord-006870-f5w6fw6q 1203 3 a a DT cord-006870-f5w6fw6q 1203 4 multicenter multicenter JJ cord-006870-f5w6fw6q 1203 5 , , , cord-006870-f5w6fw6q 1203 6 open open JJ cord-006870-f5w6fw6q 1203 7 - - HYPH cord-006870-f5w6fw6q 1203 8 label label NN cord-006870-f5w6fw6q 1203 9 phase phase NN cord-006870-f5w6fw6q 1203 10 2a 2a CD cord-006870-f5w6fw6q 1203 11 trial trial NN cord-006870-f5w6fw6q 1203 12 of of IN cord-006870-f5w6fw6q 1203 13 CN-105 CN-105 NNP cord-006870-f5w6fw6q 1203 14 in in IN cord-006870-f5w6fw6q 1203 15 patients patient NNS cord-006870-f5w6fw6q 1203 16 with with IN cord-006870-f5w6fw6q 1203 17 acute acute JJ cord-006870-f5w6fw6q 1203 18 primary primary JJ cord-006870-f5w6fw6q 1203 19 supratentorial supratentorial NN cord-006870-f5w6fw6q 1203 20 ICH ICH NNP cord-006870-f5w6fw6q 1203 21 . . . cord-006870-f5w6fw6q 1204 1 A a DT cord-006870-f5w6fw6q 1204 2 total total NN cord-006870-f5w6fw6q 1204 3 of of IN cord-006870-f5w6fw6q 1204 4 60 60 CD cord-006870-f5w6fw6q 1204 5 participants participant NNS cord-006870-f5w6fw6q 1204 6 between between IN cord-006870-f5w6fw6q 1204 7 the the DT cord-006870-f5w6fw6q 1204 8 ages age NNS cord-006870-f5w6fw6q 1204 9 30 30 CD cord-006870-f5w6fw6q 1204 10 and and CC cord-006870-f5w6fw6q 1204 11 80 80 CD cord-006870-f5w6fw6q 1204 12 years year NNS cord-006870-f5w6fw6q 1204 13 across across IN cord-006870-f5w6fw6q 1204 14 4 4 CD cord-006870-f5w6fw6q 1204 15 study study NN cord-006870-f5w6fw6q 1204 16 centers center NNS cord-006870-f5w6fw6q 1204 17 , , , cord-006870-f5w6fw6q 1204 18 with with IN cord-006870-f5w6fw6q 1204 19 a a DT cord-006870-f5w6fw6q 1204 20 confirmed confirm VBN cord-006870-f5w6fw6q 1204 21 radiographic radiographic JJ cord-006870-f5w6fw6q 1204 22 diagnosis diagnosis NN cord-006870-f5w6fw6q 1204 23 of of IN cord-006870-f5w6fw6q 1204 24 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1204 25 , , , cord-006870-f5w6fw6q 1204 26 primary primary JJ cord-006870-f5w6fw6q 1204 27 supratentorial supratentorial NN cord-006870-f5w6fw6q 1204 28 ICH ICH NNP cord-006870-f5w6fw6q 1204 29 . . . cord-006870-f5w6fw6q 1205 1 Patients patient NNS cord-006870-f5w6fw6q 1205 2 will will MD cord-006870-f5w6fw6q 1205 3 be be VB cord-006870-f5w6fw6q 1205 4 evaluated evaluate VBN cord-006870-f5w6fw6q 1205 5 for for IN cord-006870-f5w6fw6q 1205 6 eligibility eligibility NN cord-006870-f5w6fw6q 1205 7 within within IN cord-006870-f5w6fw6q 1205 8 12 12 CD cord-006870-f5w6fw6q 1205 9 hours hour NNS cord-006870-f5w6fw6q 1205 10 of of IN cord-006870-f5w6fw6q 1205 11 symptom symptom NN cord-006870-f5w6fw6q 1205 12 onset onset NN cord-006870-f5w6fw6q 1205 13 . . . cord-006870-f5w6fw6q 1206 1 Eligible eligible JJ cord-006870-f5w6fw6q 1206 2 participants participant NNS cord-006870-f5w6fw6q 1206 3 will will MD cord-006870-f5w6fw6q 1206 4 receive receive VB cord-006870-f5w6fw6q 1206 5 CN-105 CN-105 NNP cord-006870-f5w6fw6q 1207 1 intravenously intravenously RB cord-006870-f5w6fw6q 1207 2 over over IN cord-006870-f5w6fw6q 1207 3 30 30 CD cord-006870-f5w6fw6q 1207 4 - - HYPH cord-006870-f5w6fw6q 1207 5 -minute -minute CD cord-006870-f5w6fw6q 1207 6 infusion infusion NN cord-006870-f5w6fw6q 1207 7 every every DT cord-006870-f5w6fw6q 1207 8 6 6 CD cord-006870-f5w6fw6q 1207 9 hours hour NNS cord-006870-f5w6fw6q 1207 10 up up IN cord-006870-f5w6fw6q 1207 11 to to TO cord-006870-f5w6fw6q 1207 12 3 3 CD cord-006870-f5w6fw6q 1207 13 day day NN cord-006870-f5w6fw6q 1207 14 maximum maximum NN cord-006870-f5w6fw6q 1207 15 . . . cord-006870-f5w6fw6q 1208 1 Participants participant NNS cord-006870-f5w6fw6q 1208 2 will will MD cord-006870-f5w6fw6q 1208 3 be be VB cord-006870-f5w6fw6q 1208 4 monitored monitor VBN cord-006870-f5w6fw6q 1208 5 daily daily RB cord-006870-f5w6fw6q 1208 6 throughout throughout IN cord-006870-f5w6fw6q 1208 7 the the DT cord-006870-f5w6fw6q 1208 8 Treatment Treatment NNP cord-006870-f5w6fw6q 1208 9 phase phase NN cord-006870-f5w6fw6q 1208 10 and and CC cord-006870-f5w6fw6q 1208 11 receive receive VBP cord-006870-f5w6fw6q 1208 12 standard standard JJ cord-006870-f5w6fw6q 1208 13 - - HYPH cord-006870-f5w6fw6q 1208 14 of of IN cord-006870-f5w6fw6q 1208 15 - - HYPH cord-006870-f5w6fw6q 1208 16 care care NN cord-006870-f5w6fw6q 1208 17 treatment treatment NN cord-006870-f5w6fw6q 1208 18 for for IN cord-006870-f5w6fw6q 1208 19 the the DT cord-006870-f5w6fw6q 1208 20 duration duration NN cord-006870-f5w6fw6q 1208 21 of of IN cord-006870-f5w6fw6q 1208 22 the the DT cord-006870-f5w6fw6q 1208 23 study study NN cord-006870-f5w6fw6q 1208 24 . . . cord-006870-f5w6fw6q 1209 1 Primary primary NN cord-006870-f5w6fw6q 1209 2 : : : cord-006870-f5w6fw6q 1210 1 To to TO cord-006870-f5w6fw6q 1210 2 assess assess VB cord-006870-f5w6fw6q 1210 3 safety safety NN cord-006870-f5w6fw6q 1210 4 of of IN cord-006870-f5w6fw6q 1210 5 CN-105 CN-105 NNP cord-006870-f5w6fw6q 1210 6 administration administration NN cord-006870-f5w6fw6q 1210 7 in in IN cord-006870-f5w6fw6q 1210 8 primary primary JJ cord-006870-f5w6fw6q 1210 9 ICH ICH NNP cord-006870-f5w6fw6q 1210 10 . . . cord-006870-f5w6fw6q 1211 1 Secondary secondary JJ cord-006870-f5w6fw6q 1211 2 : : : cord-006870-f5w6fw6q 1211 3 To to TO cord-006870-f5w6fw6q 1211 4 evaluate evaluate VB cord-006870-f5w6fw6q 1211 5 effects effect NNS cord-006870-f5w6fw6q 1211 6 of of IN cord-006870-f5w6fw6q 1211 7 CN-105 CN-105 NNP cord-006870-f5w6fw6q 1211 8 administration administration NN cord-006870-f5w6fw6q 1211 9 on on IN cord-006870-f5w6fw6q 1211 10 30 30 CD cord-006870-f5w6fw6q 1211 11 - - HYPH cord-006870-f5w6fw6q 1211 12 -day -day CD cord-006870-f5w6fw6q 1211 13 mortality mortality NN cord-006870-f5w6fw6q 1211 14 and and CC cord-006870-f5w6fw6q 1211 15 functional functional JJ cord-006870-f5w6fw6q 1211 16 outcomes outcome NNS cord-006870-f5w6fw6q 1211 17 . . . cord-006870-f5w6fw6q 1212 1 Exploratory exploratory JJ cord-006870-f5w6fw6q 1212 2 : : : cord-006870-f5w6fw6q 1213 1 To to TO cord-006870-f5w6fw6q 1213 2 investigate investigate VB cord-006870-f5w6fw6q 1213 3 feasibility feasibility NN cord-006870-f5w6fw6q 1213 4 of of IN cord-006870-f5w6fw6q 1213 5 radiographic radiographic JJ cord-006870-f5w6fw6q 1213 6 surrogates surrogate NNS cord-006870-f5w6fw6q 1213 7 of of IN cord-006870-f5w6fw6q 1213 8 clinical clinical JJ cord-006870-f5w6fw6q 1213 9 outcomes outcome NNS cord-006870-f5w6fw6q 1213 10 using use VBG cord-006870-f5w6fw6q 1213 11 perihematomal perihematomal NN cord-006870-f5w6fw6q 1213 12 edema edema NN cord-006870-f5w6fw6q 1213 13 measurements measurement NNS cord-006870-f5w6fw6q 1213 14 on on IN cord-006870-f5w6fw6q 1213 15 serial serial JJ cord-006870-f5w6fw6q 1213 16 brain brain NN cord-006870-f5w6fw6q 1213 17 CT CT NNP cord-006870-f5w6fw6q 1213 18 and and CC cord-006870-f5w6fw6q 1213 19 MRI MRI NNP cord-006870-f5w6fw6q 1213 20 , , , cord-006870-f5w6fw6q 1213 21 and and CC cord-006870-f5w6fw6q 1213 22 investigate investigate VB cord-006870-f5w6fw6q 1213 23 feasibility feasibility NN cord-006870-f5w6fw6q 1213 24 of of IN cord-006870-f5w6fw6q 1213 25 serial serial JJ cord-006870-f5w6fw6q 1213 26 biochemical biochemical JJ cord-006870-f5w6fw6q 1213 27 markers marker NNS cord-006870-f5w6fw6q 1213 28 of of IN cord-006870-f5w6fw6q 1213 29 neuroinflammation neuroinflammation NN cord-006870-f5w6fw6q 1213 30 as as IN cord-006870-f5w6fw6q 1213 31 surrogate surrogate JJ cord-006870-f5w6fw6q 1213 32 measure measure NN cord-006870-f5w6fw6q 1213 33 of of IN cord-006870-f5w6fw6q 1213 34 perihematomal perihematomal JJ cord-006870-f5w6fw6q 1213 35 edema edema NN cord-006870-f5w6fw6q 1213 36 and and CC cord-006870-f5w6fw6q 1213 37 clinical clinical JJ cord-006870-f5w6fw6q 1213 38 outcome outcome NN cord-006870-f5w6fw6q 1213 39 . . . cord-006870-f5w6fw6q 1214 1 CN-105 CN-105 NNP cord-006870-f5w6fw6q 1214 2 represents represent VBZ cord-006870-f5w6fw6q 1214 3 a a DT cord-006870-f5w6fw6q 1214 4 first first JJ cord-006870-f5w6fw6q 1214 5 - - HYPH cord-006870-f5w6fw6q 1214 6 in in IN cord-006870-f5w6fw6q 1214 7 - - HYPH cord-006870-f5w6fw6q 1214 8 class class NN cord-006870-f5w6fw6q 1214 9 agent agent NN cord-006870-f5w6fw6q 1214 10 now now RB cord-006870-f5w6fw6q 1214 11 entering enter VBG cord-006870-f5w6fw6q 1214 12 Phase phase NN cord-006870-f5w6fw6q 1214 13 2 2 CD cord-006870-f5w6fw6q 1214 14 clinical clinical JJ cord-006870-f5w6fw6q 1214 15 trials trial NNS cord-006870-f5w6fw6q 1214 16 in in IN cord-006870-f5w6fw6q 1214 17 patients patient NNS cord-006870-f5w6fw6q 1214 18 with with IN cord-006870-f5w6fw6q 1214 19 acute acute JJ cord-006870-f5w6fw6q 1214 20 ICH ICH NNP cord-006870-f5w6fw6q 1214 21 . . . cord-006870-f5w6fw6q 1215 1 Novel novel JJ cord-006870-f5w6fw6q 1215 2 oral oral JJ cord-006870-f5w6fw6q 1215 3 anticoagulant anticoagulant NN cord-006870-f5w6fw6q 1215 4 ( ( -LRB- cord-006870-f5w6fw6q 1215 5 NOAC NOAC NNP cord-006870-f5w6fw6q 1215 6 ) ) -RRB- cord-006870-f5w6fw6q 1216 1 associated associated JJ cord-006870-f5w6fw6q 1216 2 intracranial intracranial JJ cord-006870-f5w6fw6q 1216 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1216 4 is be VBZ cord-006870-f5w6fw6q 1216 5 a a DT cord-006870-f5w6fw6q 1216 6 life life NN cord-006870-f5w6fw6q 1216 7 - - HYPH cord-006870-f5w6fw6q 1216 8 threatening threaten VBG cord-006870-f5w6fw6q 1216 9 condition condition NN cord-006870-f5w6fw6q 1216 10 for for IN cord-006870-f5w6fw6q 1216 11 which which WDT cord-006870-f5w6fw6q 1216 12 activated activate VBD cord-006870-f5w6fw6q 1216 13 prothrombin prothrombin NN cord-006870-f5w6fw6q 1216 14 complex complex JJ cord-006870-f5w6fw6q 1216 15 concentrate concentrate NN cord-006870-f5w6fw6q 1216 16 factor factor NN cord-006870-f5w6fw6q 1216 17 eight eight CD cord-006870-f5w6fw6q 1216 18 inhibitor inhibitor NN cord-006870-f5w6fw6q 1216 19 bypassing bypass VBG cord-006870-f5w6fw6q 1216 20 activity activity NN cord-006870-f5w6fw6q 1216 21 ( ( -LRB- cord-006870-f5w6fw6q 1216 22 FEIBA FEIBA NNP cord-006870-f5w6fw6q 1216 23 ) ) -RRB- cord-006870-f5w6fw6q 1216 24 may may MD cord-006870-f5w6fw6q 1216 25 be be VB cord-006870-f5w6fw6q 1216 26 used use VBN cord-006870-f5w6fw6q 1216 27 for for IN cord-006870-f5w6fw6q 1216 28 reversal reversal NN cord-006870-f5w6fw6q 1216 29 . . . cord-006870-f5w6fw6q 1217 1 Few few JJ cord-006870-f5w6fw6q 1217 2 studies study NNS cord-006870-f5w6fw6q 1217 3 report report VBP cord-006870-f5w6fw6q 1217 4 its -PRON- PRP$ cord-006870-f5w6fw6q 1217 5 use use NN cord-006870-f5w6fw6q 1217 6 in in IN cord-006870-f5w6fw6q 1217 7 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1217 8 or or CC cord-006870-f5w6fw6q 1217 9 traumatic traumatic JJ cord-006870-f5w6fw6q 1217 10 intracranial intracranial JJ cord-006870-f5w6fw6q 1217 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1217 12 . . . cord-006870-f5w6fw6q 1218 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1218 2 institutional institutional JJ cord-006870-f5w6fw6q 1218 3 protocol protocol NN cord-006870-f5w6fw6q 1218 4 is be VBZ cord-006870-f5w6fw6q 1218 5 reversal reversal JJ cord-006870-f5w6fw6q 1218 6 with with IN cord-006870-f5w6fw6q 1218 7 FEIBA FEIBA NNP cord-006870-f5w6fw6q 1218 8 25 25 CD cord-006870-f5w6fw6q 1218 9 units unit NNS cord-006870-f5w6fw6q 1218 10 / / SYM cord-006870-f5w6fw6q 1218 11 kg kg NNS cord-006870-f5w6fw6q 1218 12 and and CC cord-006870-f5w6fw6q 1218 13 escalating escalate VBG cord-006870-f5w6fw6q 1218 14 doses dose NNS cord-006870-f5w6fw6q 1218 15 as as IN cord-006870-f5w6fw6q 1218 16 needed need VBN cord-006870-f5w6fw6q 1218 17 . . . cord-006870-f5w6fw6q 1219 1 The the DT cord-006870-f5w6fw6q 1219 2 safety safety NN cord-006870-f5w6fw6q 1219 3 and and CC cord-006870-f5w6fw6q 1219 4 efficacy efficacy NN cord-006870-f5w6fw6q 1219 5 of of IN cord-006870-f5w6fw6q 1219 6 this this DT cord-006870-f5w6fw6q 1219 7 protocol protocol NN cord-006870-f5w6fw6q 1219 8 was be VBD cord-006870-f5w6fw6q 1219 9 assessed assess VBN cord-006870-f5w6fw6q 1219 10 . . . cord-006870-f5w6fw6q 1220 1 We -PRON- PRP cord-006870-f5w6fw6q 1220 2 performed perform VBD cord-006870-f5w6fw6q 1220 3 a a DT cord-006870-f5w6fw6q 1220 4 retrospective retrospective JJ cord-006870-f5w6fw6q 1220 5 review review NN cord-006870-f5w6fw6q 1220 6 of of IN cord-006870-f5w6fw6q 1220 7 adult adult NN cord-006870-f5w6fw6q 1220 8 patients patient NNS cord-006870-f5w6fw6q 1220 9 presenting present VBG cord-006870-f5w6fw6q 1220 10 to to IN cord-006870-f5w6fw6q 1220 11 a a DT cord-006870-f5w6fw6q 1220 12 Level Level NNP cord-006870-f5w6fw6q 1220 13 1 1 CD cord-006870-f5w6fw6q 1220 14 trauma trauma NN cord-006870-f5w6fw6q 1220 15 center center NN cord-006870-f5w6fw6q 1220 16 between between IN cord-006870-f5w6fw6q 1220 17 2014 2014 CD cord-006870-f5w6fw6q 1220 18 - - SYM cord-006870-f5w6fw6q 1220 19 2016 2016 CD cord-006870-f5w6fw6q 1220 20 with with IN cord-006870-f5w6fw6q 1220 21 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1220 22 or or CC cord-006870-f5w6fw6q 1220 23 traumatic traumatic JJ cord-006870-f5w6fw6q 1220 24 intracranial intracranial JJ cord-006870-f5w6fw6q 1220 25 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1220 26 while while IN cord-006870-f5w6fw6q 1220 27 on on IN cord-006870-f5w6fw6q 1220 28 a a DT cord-006870-f5w6fw6q 1220 29 NOAC NOAC NNP cord-006870-f5w6fw6q 1220 30 . . . cord-006870-f5w6fw6q 1221 1 We -PRON- PRP cord-006870-f5w6fw6q 1221 2 evaluated evaluate VBD cord-006870-f5w6fw6q 1221 3 the the DT cord-006870-f5w6fw6q 1221 4 medication medication NN cord-006870-f5w6fw6q 1221 5 they -PRON- PRP cord-006870-f5w6fw6q 1221 6 presented present VBD cord-006870-f5w6fw6q 1221 7 on on IN cord-006870-f5w6fw6q 1221 8 , , , cord-006870-f5w6fw6q 1221 9 indication indication NN cord-006870-f5w6fw6q 1221 10 for for IN cord-006870-f5w6fw6q 1221 11 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 1221 12 , , , cord-006870-f5w6fw6q 1221 13 location location NN cord-006870-f5w6fw6q 1221 14 and and CC cord-006870-f5w6fw6q 1221 15 size size NN cord-006870-f5w6fw6q 1221 16 of of IN cord-006870-f5w6fw6q 1221 17 the the DT cord-006870-f5w6fw6q 1221 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1221 19 , , , cord-006870-f5w6fw6q 1221 20 presentation presentation NN cord-006870-f5w6fw6q 1221 21 GCS GCS NNP cord-006870-f5w6fw6q 1221 22 , , , cord-006870-f5w6fw6q 1221 23 dosage dosage NN cord-006870-f5w6fw6q 1221 24 of of IN cord-006870-f5w6fw6q 1221 25 FEIBA FEIBA NNP cord-006870-f5w6fw6q 1221 26 recieved recieve VBD cord-006870-f5w6fw6q 1221 27 , , , cord-006870-f5w6fw6q 1221 28 change change NN cord-006870-f5w6fw6q 1221 29 in in IN cord-006870-f5w6fw6q 1221 30 size size NN cord-006870-f5w6fw6q 1221 31 of of IN cord-006870-f5w6fw6q 1221 32 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1221 33 on on IN cord-006870-f5w6fw6q 1221 34 serial serial JJ cord-006870-f5w6fw6q 1221 35 imaging imaging NN cord-006870-f5w6fw6q 1221 36 as as RB cord-006870-f5w6fw6q 1221 37 well well RB cord-006870-f5w6fw6q 1221 38 as as IN cord-006870-f5w6fw6q 1221 39 time time NN cord-006870-f5w6fw6q 1221 40 between between IN cord-006870-f5w6fw6q 1221 41 serial serial JJ cord-006870-f5w6fw6q 1221 42 images image NNS cord-006870-f5w6fw6q 1221 43 , , , cord-006870-f5w6fw6q 1221 44 complications complication NNS cord-006870-f5w6fw6q 1221 45 from from IN cord-006870-f5w6fw6q 1221 46 reversal reversal NN cord-006870-f5w6fw6q 1221 47 , , , cord-006870-f5w6fw6q 1221 48 and and CC cord-006870-f5w6fw6q 1221 49 need need VB cord-006870-f5w6fw6q 1221 50 for for IN cord-006870-f5w6fw6q 1221 51 blood blood NN cord-006870-f5w6fw6q 1221 52 product product NN cord-006870-f5w6fw6q 1221 53 transfusion transfusion NN cord-006870-f5w6fw6q 1221 54 . . . cord-006870-f5w6fw6q 1222 1 We -PRON- PRP cord-006870-f5w6fw6q 1222 2 identified identify VBD cord-006870-f5w6fw6q 1222 3 19 19 CD cord-006870-f5w6fw6q 1222 4 patients patient NNS cord-006870-f5w6fw6q 1222 5 with with IN cord-006870-f5w6fw6q 1222 6 an an DT cord-006870-f5w6fw6q 1222 7 acute acute JJ cord-006870-f5w6fw6q 1222 8 intracranial intracranial JJ cord-006870-f5w6fw6q 1222 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1222 10 while while IN cord-006870-f5w6fw6q 1222 11 on on IN cord-006870-f5w6fw6q 1222 12 NOACs noac NNS cord-006870-f5w6fw6q 1222 13 . . . cord-006870-f5w6fw6q 1223 1 Patients patient NNS cord-006870-f5w6fw6q 1223 2 underwent undergo VBD cord-006870-f5w6fw6q 1223 3 a a DT cord-006870-f5w6fw6q 1223 4 baseline baseline JJ cord-006870-f5w6fw6q 1223 5 head head NN cord-006870-f5w6fw6q 1223 6 CT CT NNP cord-006870-f5w6fw6q 1223 7 documenting document VBG cord-006870-f5w6fw6q 1223 8 acute acute JJ cord-006870-f5w6fw6q 1223 9 intracranial intracranial JJ cord-006870-f5w6fw6q 1223 10 blood blood NN cord-006870-f5w6fw6q 1223 11 , , , cord-006870-f5w6fw6q 1223 12 were be VBD cord-006870-f5w6fw6q 1223 13 reversed reverse VBN cord-006870-f5w6fw6q 1223 14 with with IN cord-006870-f5w6fw6q 1223 15 FEIBA FEIBA NNP cord-006870-f5w6fw6q 1223 16 ( ( -LRB- cord-006870-f5w6fw6q 1223 17 25 25 CD cord-006870-f5w6fw6q 1223 18 u u NNP cord-006870-f5w6fw6q 1223 19 / / SYM cord-006870-f5w6fw6q 1223 20 kg kg NNP cord-006870-f5w6fw6q 1223 21 ) ) -RRB- cord-006870-f5w6fw6q 1223 22 , , , cord-006870-f5w6fw6q 1223 23 and and CC cord-006870-f5w6fw6q 1223 24 underwent undergo VBD cord-006870-f5w6fw6q 1223 25 repeat repeat NN cord-006870-f5w6fw6q 1223 26 imaging image VBG cord-006870-f5w6fw6q 1223 27 6 6 CD cord-006870-f5w6fw6q 1223 28 hours hour NNS cord-006870-f5w6fw6q 1223 29 later later RB cord-006870-f5w6fw6q 1223 30 per per IN cord-006870-f5w6fw6q 1223 31 protocol protocol NN cord-006870-f5w6fw6q 1223 32 . . . cord-006870-f5w6fw6q 1224 1 Ten ten CD cord-006870-f5w6fw6q 1224 2 ( ( -LRB- cord-006870-f5w6fw6q 1224 3 59 59 CD cord-006870-f5w6fw6q 1224 4 % % NN cord-006870-f5w6fw6q 1224 5 , , , cord-006870-f5w6fw6q 1224 6 10/17 10/17 CD cord-006870-f5w6fw6q 1224 7 ) ) -RRB- cord-006870-f5w6fw6q 1224 8 patients patient NNS cord-006870-f5w6fw6q 1224 9 had have VBD cord-006870-f5w6fw6q 1224 10 no no DT cord-006870-f5w6fw6q 1224 11 increase increase NN cord-006870-f5w6fw6q 1224 12 in in IN cord-006870-f5w6fw6q 1224 13 hematoma hematoma NN cord-006870-f5w6fw6q 1224 14 volume volume NN cord-006870-f5w6fw6q 1224 15 on on IN cord-006870-f5w6fw6q 1224 16 repeat repeat NN cord-006870-f5w6fw6q 1224 17 imaging imaging NN cord-006870-f5w6fw6q 1224 18 . . . cord-006870-f5w6fw6q 1225 1 Two two CD cord-006870-f5w6fw6q 1225 2 underwent undergo VBD cord-006870-f5w6fw6q 1225 3 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 1225 4 procedures procedure NNS cord-006870-f5w6fw6q 1225 5 ( ( -LRB- cord-006870-f5w6fw6q 1225 6 aneurysm aneurysm NN cord-006870-f5w6fw6q 1225 7 coiling coiling NN cord-006870-f5w6fw6q 1225 8 , , , cord-006870-f5w6fw6q 1225 9 sub sub JJ cord-006870-f5w6fw6q 1225 10 - - JJ cord-006870-f5w6fw6q 1225 11 occipital occipital JJ cord-006870-f5w6fw6q 1225 12 craniectomy craniectomy NN cord-006870-f5w6fw6q 1225 13 ) ) -RRB- cord-006870-f5w6fw6q 1225 14 without without IN cord-006870-f5w6fw6q 1225 15 intra intra JJ cord-006870-f5w6fw6q 1225 16 - - JJ cord-006870-f5w6fw6q 1225 17 operative operative JJ cord-006870-f5w6fw6q 1225 18 bleeding bleed VBG cord-006870-f5w6fw6q 1225 19 complications complication NNS cord-006870-f5w6fw6q 1225 20 . . . cord-006870-f5w6fw6q 1226 1 Five five CD cord-006870-f5w6fw6q 1226 2 ( ( -LRB- cord-006870-f5w6fw6q 1226 3 29 29 CD cord-006870-f5w6fw6q 1226 4 % % NN cord-006870-f5w6fw6q 1226 5 5/17 5/17 CD cord-006870-f5w6fw6q 1226 6 ) ) -RRB- cord-006870-f5w6fw6q 1226 7 patients patient NNS cord-006870-f5w6fw6q 1226 8 had have VBD cord-006870-f5w6fw6q 1226 9 clinically clinically RB cord-006870-f5w6fw6q 1226 10 insignificant insignificant JJ cord-006870-f5w6fw6q 1226 11 increase increase NN cord-006870-f5w6fw6q 1226 12 in in IN cord-006870-f5w6fw6q 1226 13 size size NN cord-006870-f5w6fw6q 1226 14 of of IN cord-006870-f5w6fw6q 1226 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1226 16 . . . cord-006870-f5w6fw6q 1227 1 Of of IN cord-006870-f5w6fw6q 1227 2 those those DT cord-006870-f5w6fw6q 1227 3 , , , cord-006870-f5w6fw6q 1227 4 one one CD cord-006870-f5w6fw6q 1227 5 underwent undergo VBD cord-006870-f5w6fw6q 1227 6 a a DT cord-006870-f5w6fw6q 1227 7 subsequent subsequent JJ cord-006870-f5w6fw6q 1227 8 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 1227 9 procedure procedure NN cord-006870-f5w6fw6q 1227 10 , , , cord-006870-f5w6fw6q 1227 11 which which WDT cord-006870-f5w6fw6q 1227 12 was be VBD cord-006870-f5w6fw6q 1227 13 already already RB cord-006870-f5w6fw6q 1227 14 anticipated anticipate VBN cord-006870-f5w6fw6q 1227 15 . . . cord-006870-f5w6fw6q 1228 1 Two two CD cord-006870-f5w6fw6q 1228 2 ( ( -LRB- cord-006870-f5w6fw6q 1228 3 12 12 CD cord-006870-f5w6fw6q 1228 4 % % NN cord-006870-f5w6fw6q 1228 5 , , , cord-006870-f5w6fw6q 1228 6 2/17 2/17 CD cord-006870-f5w6fw6q 1228 7 ) ) -RRB- cord-006870-f5w6fw6q 1228 8 patients patient NNS cord-006870-f5w6fw6q 1228 9 had have VBD cord-006870-f5w6fw6q 1228 10 clinically clinically RB cord-006870-f5w6fw6q 1228 11 significant significant JJ cord-006870-f5w6fw6q 1228 12 hematoma hematoma NN cord-006870-f5w6fw6q 1228 13 enlargement enlargement NN cord-006870-f5w6fw6q 1228 14 . . . cord-006870-f5w6fw6q 1229 1 Of of IN cord-006870-f5w6fw6q 1229 2 those those DT cord-006870-f5w6fw6q 1229 3 , , , cord-006870-f5w6fw6q 1229 4 one one CD cord-006870-f5w6fw6q 1229 5 underwent undergo VBD cord-006870-f5w6fw6q 1229 6 urgent urgent JJ cord-006870-f5w6fw6q 1229 7 craniectomy craniectomy NN cord-006870-f5w6fw6q 1229 8 ( ( -LRB- cord-006870-f5w6fw6q 1229 9 indicated indicate VBN cord-006870-f5w6fw6q 1229 10 based base VBN cord-006870-f5w6fw6q 1229 11 on on IN cord-006870-f5w6fw6q 1229 12 initial initial JJ cord-006870-f5w6fw6q 1229 13 presentation presentation NN cord-006870-f5w6fw6q 1229 14 ) ) -RRB- cord-006870-f5w6fw6q 1229 15 and and CC cord-006870-f5w6fw6q 1229 16 one one CD cord-006870-f5w6fw6q 1229 17 required require VBD cord-006870-f5w6fw6q 1229 18 a a DT cord-006870-f5w6fw6q 1229 19 ventriculostomy ventriculostomy NN cord-006870-f5w6fw6q 1229 20 for for IN cord-006870-f5w6fw6q 1229 21 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 1229 22 . . . cord-006870-f5w6fw6q 1230 1 Two two CD cord-006870-f5w6fw6q 1230 2 patients patient NNS cord-006870-f5w6fw6q 1230 3 had have VBD cord-006870-f5w6fw6q 1230 4 no no DT cord-006870-f5w6fw6q 1230 5 repeat repeat NN cord-006870-f5w6fw6q 1230 6 imaging imaging NN cord-006870-f5w6fw6q 1230 7 . . . cord-006870-f5w6fw6q 1231 1 Adjusted adjust VBN cord-006870-f5w6fw6q 1231 2 dose dose NN cord-006870-f5w6fw6q 1231 3 FEIBA FEIBA NNP cord-006870-f5w6fw6q 1231 4 ( ( -LRB- cord-006870-f5w6fw6q 1231 5 25 25 CD cord-006870-f5w6fw6q 1231 6 units unit NNS cord-006870-f5w6fw6q 1231 7 / / SYM cord-006870-f5w6fw6q 1231 8 kg kg NN cord-006870-f5w6fw6q 1231 9 ) ) -RRB- cord-006870-f5w6fw6q 1231 10 may may MD cord-006870-f5w6fw6q 1231 11 be be VB cord-006870-f5w6fw6q 1231 12 an an DT cord-006870-f5w6fw6q 1231 13 effective effective JJ cord-006870-f5w6fw6q 1231 14 alternative alternative NN cord-006870-f5w6fw6q 1231 15 to to IN cord-006870-f5w6fw6q 1231 16 standard standard JJ cord-006870-f5w6fw6q 1231 17 dose dose NN cord-006870-f5w6fw6q 1231 18 ( ( -LRB- cord-006870-f5w6fw6q 1231 19 50 50 CD cord-006870-f5w6fw6q 1231 20 unit unit NN cord-006870-f5w6fw6q 1231 21 / / SYM cord-006870-f5w6fw6q 1231 22 kg kg NNP cord-006870-f5w6fw6q 1231 23 ) ) -RRB- cord-006870-f5w6fw6q 1231 24 for for IN cord-006870-f5w6fw6q 1231 25 reversal reversal NN cord-006870-f5w6fw6q 1231 26 of of IN cord-006870-f5w6fw6q 1231 27 NOACs noac NNS cord-006870-f5w6fw6q 1231 28 in in IN cord-006870-f5w6fw6q 1231 29 acute acute JJ cord-006870-f5w6fw6q 1231 30 intracranial intracranial JJ cord-006870-f5w6fw6q 1231 31 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1231 32 . . . cord-006870-f5w6fw6q 1232 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1232 2 experience experience NN cord-006870-f5w6fw6q 1232 3 showed show VBD cord-006870-f5w6fw6q 1232 4 clinically clinically RB cord-006870-f5w6fw6q 1232 5 significant significant JJ cord-006870-f5w6fw6q 1232 6 hematoma hematoma NN cord-006870-f5w6fw6q 1232 7 expansion expansion NN cord-006870-f5w6fw6q 1232 8 in in IN cord-006870-f5w6fw6q 1232 9 12 12 CD cord-006870-f5w6fw6q 1232 10 % % NN cord-006870-f5w6fw6q 1232 11 of of IN cord-006870-f5w6fw6q 1232 12 patients patient NNS cord-006870-f5w6fw6q 1232 13 and and CC cord-006870-f5w6fw6q 1232 14 no no DT cord-006870-f5w6fw6q 1232 15 increase increase NN cord-006870-f5w6fw6q 1232 16 in in IN cord-006870-f5w6fw6q 1232 17 unplanned unplanned JJ cord-006870-f5w6fw6q 1232 18 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 1232 19 procedures procedure NNS cord-006870-f5w6fw6q 1232 20 after after IN cord-006870-f5w6fw6q 1232 21 reversal reversal NN cord-006870-f5w6fw6q 1232 22 with with IN cord-006870-f5w6fw6q 1232 23 FEIBA FEIBA NNP cord-006870-f5w6fw6q 1232 24 . . . cord-006870-f5w6fw6q 1233 1 Here here RB cord-006870-f5w6fw6q 1233 2 we -PRON- PRP cord-006870-f5w6fw6q 1233 3 sought seek VBD cord-006870-f5w6fw6q 1233 4 to to TO cord-006870-f5w6fw6q 1233 5 determine determine VB cord-006870-f5w6fw6q 1233 6 if if IN cord-006870-f5w6fw6q 1233 7 there there EX cord-006870-f5w6fw6q 1233 8 is be VBZ cord-006870-f5w6fw6q 1233 9 an an DT cord-006870-f5w6fw6q 1233 10 association association NN cord-006870-f5w6fw6q 1233 11 between between IN cord-006870-f5w6fw6q 1233 12 recanalization recanalization NN cord-006870-f5w6fw6q 1233 13 success success NN cord-006870-f5w6fw6q 1233 14 and and CC cord-006870-f5w6fw6q 1233 15 rate rate NN cord-006870-f5w6fw6q 1233 16 of of IN cord-006870-f5w6fw6q 1233 17 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1233 18 transformation transformation NN cord-006870-f5w6fw6q 1233 19 amongst amongst IN cord-006870-f5w6fw6q 1233 20 patients patient NNS cord-006870-f5w6fw6q 1233 21 who who WP cord-006870-f5w6fw6q 1233 22 have have VBP cord-006870-f5w6fw6q 1233 23 undergone undergo VBN cord-006870-f5w6fw6q 1233 24 intra intra JJ cord-006870-f5w6fw6q 1233 25 - - JJ cord-006870-f5w6fw6q 1233 26 arterial arterial JJ cord-006870-f5w6fw6q 1233 27 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 1233 28 for for IN cord-006870-f5w6fw6q 1233 29 ischemic ischemic JJ cord-006870-f5w6fw6q 1233 30 stroke stroke NN cord-006870-f5w6fw6q 1233 31 secondary secondary JJ cord-006870-f5w6fw6q 1233 32 to to IN cord-006870-f5w6fw6q 1233 33 anterior anterior JJ cord-006870-f5w6fw6q 1233 34 circulation circulation NN cord-006870-f5w6fw6q 1233 35 large large JJ cord-006870-f5w6fw6q 1233 36 vessel vessel NN cord-006870-f5w6fw6q 1233 37 occlusion occlusion NN cord-006870-f5w6fw6q 1233 38 ( ( -LRB- cord-006870-f5w6fw6q 1233 39 LVO LVO NNP cord-006870-f5w6fw6q 1233 40 ) ) -RRB- cord-006870-f5w6fw6q 1233 41 , , . cord-006870-f5w6fw6q 1234 1 many many JJ cord-006870-f5w6fw6q 1234 2 treated treat VBN cord-006870-f5w6fw6q 1234 3 at at IN cord-006870-f5w6fw6q 1234 4 extended extended JJ cord-006870-f5w6fw6q 1234 5 time time NN cord-006870-f5w6fw6q 1234 6 from from IN cord-006870-f5w6fw6q 1234 7 last last RB cord-006870-f5w6fw6q 1234 8 seen see VBN cord-006870-f5w6fw6q 1234 9 well well UH cord-006870-f5w6fw6q 1234 10 ( ( -LRB- cord-006870-f5w6fw6q 1234 11 LSW LSW NNP cord-006870-f5w6fw6q 1234 12 ) ) -RRB- cord-006870-f5w6fw6q 1234 13 after after IN cord-006870-f5w6fw6q 1234 14 MRI MRI NNP cord-006870-f5w6fw6q 1234 15 assessment assessment NN cord-006870-f5w6fw6q 1234 16 . . . cord-006870-f5w6fw6q 1235 1 Stroke stroke NN cord-006870-f5w6fw6q 1235 2 patients patient NNS cord-006870-f5w6fw6q 1235 3 with with IN cord-006870-f5w6fw6q 1236 1 anterior anterior NNP cord-006870-f5w6fw6q 1236 2 circulation circulation NN cord-006870-f5w6fw6q 1236 3 LVO LVO NNP cord-006870-f5w6fw6q 1236 4 treated treat VBD cord-006870-f5w6fw6q 1236 5 with with IN cord-006870-f5w6fw6q 1236 6 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 1236 7 between between IN cord-006870-f5w6fw6q 1236 8 April April NNP cord-006870-f5w6fw6q 1236 9 , , , cord-006870-f5w6fw6q 1236 10 2011 2011 CD cord-006870-f5w6fw6q 1236 11 to to IN cord-006870-f5w6fw6q 1236 12 June June NNP cord-006870-f5w6fw6q 1236 13 , , , cord-006870-f5w6fw6q 1236 14 2017 2017 CD cord-006870-f5w6fw6q 1236 15 were be VBD cord-006870-f5w6fw6q 1236 16 studied study VBN cord-006870-f5w6fw6q 1236 17 . . . cord-006870-f5w6fw6q 1237 1 Group group NN cord-006870-f5w6fw6q 1237 2 - - HYPH cord-006870-f5w6fw6q 1237 3 wise wise JJ cord-006870-f5w6fw6q 1237 4 comparisons comparison NNS cord-006870-f5w6fw6q 1237 5 were be VBD cord-006870-f5w6fw6q 1237 6 made make VBN cord-006870-f5w6fw6q 1237 7 between between IN cord-006870-f5w6fw6q 1237 8 patients patient NNS cord-006870-f5w6fw6q 1237 9 with with IN cord-006870-f5w6fw6q 1237 10 post post JJ cord-006870-f5w6fw6q 1237 11 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 1237 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1237 13 ( ( -LRB- cord-006870-f5w6fw6q 1237 14 as as IN cord-006870-f5w6fw6q 1237 15 confirmed confirm VBN cord-006870-f5w6fw6q 1237 16 by by IN cord-006870-f5w6fw6q 1237 17 a a DT cord-006870-f5w6fw6q 1237 18 single single JJ cord-006870-f5w6fw6q 1237 19 , , , cord-006870-f5w6fw6q 1237 20 blinded blinded JJ cord-006870-f5w6fw6q 1237 21 neuro neuro NNP cord-006870-f5w6fw6q 1237 22 - - HYPH cord-006870-f5w6fw6q 1237 23 radiologist radiologist NNP cord-006870-f5w6fw6q 1237 24 reviewer reviewer NN cord-006870-f5w6fw6q 1237 25 ) ) -RRB- cord-006870-f5w6fw6q 1237 26 and and CC cord-006870-f5w6fw6q 1237 27 patients patient NNS cord-006870-f5w6fw6q 1237 28 without without IN cord-006870-f5w6fw6q 1237 29 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1237 30 . . . cord-006870-f5w6fw6q 1238 1 Failed fail VBN cord-006870-f5w6fw6q 1238 2 or or CC cord-006870-f5w6fw6q 1238 3 incomplete incomplete JJ cord-006870-f5w6fw6q 1238 4 recanalization recanalization NN cord-006870-f5w6fw6q 1238 5 was be VBD cord-006870-f5w6fw6q 1238 6 defined define VBN cord-006870-f5w6fw6q 1238 7 as as IN cord-006870-f5w6fw6q 1238 8 mTICI mTICI NNP cord-006870-f5w6fw6q 1238 9 < < XX cord-006870-f5w6fw6q 1238 10 2B. 2b. CD cord-006870-f5w6fw6q 1238 11 Symptomatic symptomatic JJ cord-006870-f5w6fw6q 1238 12 intracranial intracranial JJ cord-006870-f5w6fw6q 1238 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1238 14 ( ( -LRB- cord-006870-f5w6fw6q 1238 15 SICH SICH NNP cord-006870-f5w6fw6q 1238 16 ) ) -RRB- cord-006870-f5w6fw6q 1238 17 was be VBD cord-006870-f5w6fw6q 1238 18 defined define VBN cord-006870-f5w6fw6q 1238 19 as as IN cord-006870-f5w6fw6q 1238 20 validated validate VBN cord-006870-f5w6fw6q 1238 21 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1238 22 conversion conversion NN cord-006870-f5w6fw6q 1238 23 or or CC cord-006870-f5w6fw6q 1238 24 parenchymal parenchymal JJ cord-006870-f5w6fw6q 1238 25 hematoma hematoma NN cord-006870-f5w6fw6q 1238 26 plus plus CC cord-006870-f5w6fw6q 1238 27 4 4 CD cord-006870-f5w6fw6q 1238 28 point point NN cord-006870-f5w6fw6q 1238 29 decrease decrease NN cord-006870-f5w6fw6q 1238 30 in in IN cord-006870-f5w6fw6q 1238 31 NIHSSS NIHSSS NNP cord-006870-f5w6fw6q 1238 32 . . . cord-006870-f5w6fw6q 1239 1 Pertinent pertinent JJ cord-006870-f5w6fw6q 1239 2 baseline baseline JJ cord-006870-f5w6fw6q 1239 3 characteristics characteristic NNS cord-006870-f5w6fw6q 1239 4 were be VBD cord-006870-f5w6fw6q 1239 5 recorded record VBN cord-006870-f5w6fw6q 1239 6 and and CC cord-006870-f5w6fw6q 1239 7 analyzed analyze VBN cord-006870-f5w6fw6q 1239 8 . . . cord-006870-f5w6fw6q 1240 1 SICH SICH NNP cord-006870-f5w6fw6q 1240 2 was be VBD cord-006870-f5w6fw6q 1240 3 more more RBR cord-006870-f5w6fw6q 1240 4 prevalent prevalent JJ cord-006870-f5w6fw6q 1240 5 amongst amongst IN cord-006870-f5w6fw6q 1240 6 patients patient NNS cord-006870-f5w6fw6q 1240 7 with with IN cord-006870-f5w6fw6q 1240 8 TICI<2B tici<2b NN cord-006870-f5w6fw6q 1240 9 recanalization recanalization NN cord-006870-f5w6fw6q 1240 10 ( ( -LRB- cord-006870-f5w6fw6q 1240 11 OR or CC cord-006870-f5w6fw6q 1240 12 2.76 2.76 CD cord-006870-f5w6fw6q 1240 13 [ [ -LRB- cord-006870-f5w6fw6q 1240 14 95CI 95ci CD cord-006870-f5w6fw6q 1240 15 1.33 1.33 CD cord-006870-f5w6fw6q 1240 16 -5.71 -5.71 CD cord-006870-f5w6fw6q 1240 17 ] ] -RRB- cord-006870-f5w6fw6q 1240 18 ) ) -RRB- cord-006870-f5w6fw6q 1240 19 . . . cord-006870-f5w6fw6q 1241 1 Interestingly interestingly RB cord-006870-f5w6fw6q 1241 2 there there EX cord-006870-f5w6fw6q 1241 3 was be VBD cord-006870-f5w6fw6q 1241 4 a a DT cord-006870-f5w6fw6q 1241 5 low low JJ cord-006870-f5w6fw6q 1241 6 rate rate NN cord-006870-f5w6fw6q 1241 7 of of IN cord-006870-f5w6fw6q 1241 8 SICH SICH NNP cord-006870-f5w6fw6q 1241 9 amongst amongst IN cord-006870-f5w6fw6q 1241 10 patients patient NNS cord-006870-f5w6fw6q 1241 11 with with IN cord-006870-f5w6fw6q 1241 12 TICI=0 tici=0 NN cord-006870-f5w6fw6q 1241 13 recanalization recanalization NN cord-006870-f5w6fw6q 1241 14 ( ( -LRB- cord-006870-f5w6fw6q 1241 15 2/12 2/12 CD cord-006870-f5w6fw6q 1241 16 [ [ -LRB- cord-006870-f5w6fw6q 1241 17 16.7 16.7 CD cord-006870-f5w6fw6q 1241 18 % % NN cord-006870-f5w6fw6q 1241 19 ] ] -RRB- cord-006870-f5w6fw6q 1241 20 ) ) -RRB- cord-006870-f5w6fw6q 1241 21 . . . cord-006870-f5w6fw6q 1242 1 Although although IN cord-006870-f5w6fw6q 1242 2 many many JJ cord-006870-f5w6fw6q 1242 3 patients patient NNS cord-006870-f5w6fw6q 1242 4 were be VBD cord-006870-f5w6fw6q 1242 5 treated treat VBN cord-006870-f5w6fw6q 1242 6 at at IN cord-006870-f5w6fw6q 1242 7 advanced advanced JJ cord-006870-f5w6fw6q 1242 8 time time NN cord-006870-f5w6fw6q 1242 9 LSW LSW NNP cord-006870-f5w6fw6q 1242 10 no no DT cord-006870-f5w6fw6q 1242 11 excess excess JJ cord-006870-f5w6fw6q 1242 12 rate rate NN cord-006870-f5w6fw6q 1242 13 of of IN cord-006870-f5w6fw6q 1242 14 SICH SICH NNP cord-006870-f5w6fw6q 1242 15 was be VBD cord-006870-f5w6fw6q 1242 16 observed observe VBN cord-006870-f5w6fw6q 1242 17 . . . cord-006870-f5w6fw6q 1243 1 Baseline baseline JJ cord-006870-f5w6fw6q 1243 2 characteristics characteristic NNS cord-006870-f5w6fw6q 1243 3 including include VBG cord-006870-f5w6fw6q 1243 4 age age NN cord-006870-f5w6fw6q 1243 5 , , , cord-006870-f5w6fw6q 1243 6 presentation presentation NN cord-006870-f5w6fw6q 1243 7 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1243 8 , , , cord-006870-f5w6fw6q 1243 9 and and CC cord-006870-f5w6fw6q 1243 10 presentation presentation NN cord-006870-f5w6fw6q 1243 11 ASPECTS aspect NNS cord-006870-f5w6fw6q 1243 12 were be VBD cord-006870-f5w6fw6q 1243 13 similar similar JJ cord-006870-f5w6fw6q 1243 14 among among IN cord-006870-f5w6fw6q 1243 15 the the DT cord-006870-f5w6fw6q 1243 16 two two CD cord-006870-f5w6fw6q 1243 17 groups group NNS cord-006870-f5w6fw6q 1243 18 . . . cord-006870-f5w6fw6q 1244 1 Rates rate NNS cord-006870-f5w6fw6q 1244 2 of of IN cord-006870-f5w6fw6q 1244 3 SICH SICH NNP cord-006870-f5w6fw6q 1244 4 are be VBP cord-006870-f5w6fw6q 1244 5 low low JJ cord-006870-f5w6fw6q 1244 6 after after IN cord-006870-f5w6fw6q 1244 7 successful successful JJ cord-006870-f5w6fw6q 1244 8 MRI MRI NNP cord-006870-f5w6fw6q 1244 9 seleted selete VBD cord-006870-f5w6fw6q 1244 10 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 1244 11 regardless regardless RB cord-006870-f5w6fw6q 1244 12 ot ot IN cord-006870-f5w6fw6q 1244 13 time time NN cord-006870-f5w6fw6q 1244 14 LSW LSW NNP cord-006870-f5w6fw6q 1244 15 . . . cord-006870-f5w6fw6q 1245 1 Patients patient NNS cord-006870-f5w6fw6q 1245 2 with with IN cord-006870-f5w6fw6q 1245 3 poor poor JJ cord-006870-f5w6fw6q 1245 4 recanalization recanalization NN cord-006870-f5w6fw6q 1245 5 show show NN cord-006870-f5w6fw6q 1245 6 increased increase VBN cord-006870-f5w6fw6q 1245 7 rates rate NNS cord-006870-f5w6fw6q 1245 8 of of IN cord-006870-f5w6fw6q 1245 9 SICH SICH NNP cord-006870-f5w6fw6q 1245 10 in in IN cord-006870-f5w6fw6q 1245 11 keeping keep VBG cord-006870-f5w6fw6q 1245 12 with with IN cord-006870-f5w6fw6q 1245 13 past past JJ cord-006870-f5w6fw6q 1245 14 literature literature NN cord-006870-f5w6fw6q 1245 15 . . . cord-006870-f5w6fw6q 1246 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1246 2 data datum NNS cord-006870-f5w6fw6q 1246 3 suggest suggest VBP cord-006870-f5w6fw6q 1246 4 that that IN cord-006870-f5w6fw6q 1246 5 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 1246 6 after after IN cord-006870-f5w6fw6q 1246 7 MRI MRI NNP cord-006870-f5w6fw6q 1246 8 selection selection NN cord-006870-f5w6fw6q 1246 9 may may MD cord-006870-f5w6fw6q 1246 10 be be VB cord-006870-f5w6fw6q 1246 11 safe safe JJ cord-006870-f5w6fw6q 1246 12 and and CC cord-006870-f5w6fw6q 1246 13 effective effective JJ cord-006870-f5w6fw6q 1246 14 for for IN cord-006870-f5w6fw6q 1246 15 patients patient NNS cord-006870-f5w6fw6q 1246 16 at at IN cord-006870-f5w6fw6q 1246 17 extended extended JJ cord-006870-f5w6fw6q 1246 18 time time NN cord-006870-f5w6fw6q 1246 19 LSW LSW NNP cord-006870-f5w6fw6q 1246 20 of of IN cord-006870-f5w6fw6q 1246 21 tor tor NN cord-006870-f5w6fw6q 1246 22 patients patient NNS cord-006870-f5w6fw6q 1246 23 with with IN cord-006870-f5w6fw6q 1246 24 unknown unknown JJ cord-006870-f5w6fw6q 1246 25 LSW lsw NN cord-006870-f5w6fw6q 1246 26 . . . cord-006870-f5w6fw6q 1247 1 CTA CTA NNP cord-006870-f5w6fw6q 1247 2 spot spot NN cord-006870-f5w6fw6q 1247 3 sign sign NN cord-006870-f5w6fw6q 1247 4 is be VBZ cord-006870-f5w6fw6q 1247 5 associated associate VBN cord-006870-f5w6fw6q 1247 6 with with IN cord-006870-f5w6fw6q 1247 7 hematoma hematoma NN cord-006870-f5w6fw6q 1247 8 growth growth NN cord-006870-f5w6fw6q 1247 9 , , , cord-006870-f5w6fw6q 1247 10 a a DT cord-006870-f5w6fw6q 1247 11 common common JJ cord-006870-f5w6fw6q 1247 12 complication complication NN cord-006870-f5w6fw6q 1247 13 of of IN cord-006870-f5w6fw6q 1247 14 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1247 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1247 16 ( ( -LRB- cord-006870-f5w6fw6q 1247 17 ICH ICH NNP cord-006870-f5w6fw6q 1247 18 ) ) -RRB- cord-006870-f5w6fw6q 1247 19 that that WDT cord-006870-f5w6fw6q 1247 20 portends portend VBZ cord-006870-f5w6fw6q 1247 21 worse bad JJR cord-006870-f5w6fw6q 1247 22 outcomes outcome NNS cord-006870-f5w6fw6q 1247 23 . . . cord-006870-f5w6fw6q 1248 1 Magnesium magnesium NN cord-006870-f5w6fw6q 1248 2 and and CC cord-006870-f5w6fw6q 1248 3 calcium calcium NN cord-006870-f5w6fw6q 1248 4 are be VBP cord-006870-f5w6fw6q 1248 5 cofactors cofactor NNS cord-006870-f5w6fw6q 1248 6 in in IN cord-006870-f5w6fw6q 1248 7 the the DT cord-006870-f5w6fw6q 1248 8 clotting clotting NN cord-006870-f5w6fw6q 1248 9 cascade cascade NN cord-006870-f5w6fw6q 1248 10 and and CC cord-006870-f5w6fw6q 1248 11 for for IN cord-006870-f5w6fw6q 1248 12 platelet platelet NN cord-006870-f5w6fw6q 1248 13 aggregation aggregation NN cord-006870-f5w6fw6q 1248 14 . . . cord-006870-f5w6fw6q 1249 1 We -PRON- PRP cord-006870-f5w6fw6q 1249 2 tested test VBD cord-006870-f5w6fw6q 1249 3 the the DT cord-006870-f5w6fw6q 1249 4 hypothesis hypothesis NN cord-006870-f5w6fw6q 1249 5 that that IN cord-006870-f5w6fw6q 1249 6 magnesium magnesium NN cord-006870-f5w6fw6q 1249 7 and and CC cord-006870-f5w6fw6q 1249 8 calcium calcium NN cord-006870-f5w6fw6q 1249 9 levels level NNS cord-006870-f5w6fw6q 1249 10 are be VBP cord-006870-f5w6fw6q 1249 11 associated associate VBN cord-006870-f5w6fw6q 1249 12 with with IN cord-006870-f5w6fw6q 1249 13 the the DT cord-006870-f5w6fw6q 1249 14 presence presence NN cord-006870-f5w6fw6q 1249 15 of of IN cord-006870-f5w6fw6q 1249 16 the the DT cord-006870-f5w6fw6q 1249 17 CTA CTA NNP cord-006870-f5w6fw6q 1249 18 spot spot NN cord-006870-f5w6fw6q 1249 19 sign sign NN cord-006870-f5w6fw6q 1249 20 . . . cord-006870-f5w6fw6q 1250 1 Patients patient NNS cord-006870-f5w6fw6q 1250 2 with with IN cord-006870-f5w6fw6q 1250 3 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1250 4 ICH ICH NNP cord-006870-f5w6fw6q 1250 5 presenting present VBG cord-006870-f5w6fw6q 1250 6 to to IN cord-006870-f5w6fw6q 1250 7 Northwestern Northwestern NNP cord-006870-f5w6fw6q 1250 8 Memorial Memorial NNP cord-006870-f5w6fw6q 1250 9 Hospital Hospital NNP cord-006870-f5w6fw6q 1250 10 were be VBD cord-006870-f5w6fw6q 1250 11 identified identify VBN cord-006870-f5w6fw6q 1250 12 from from IN cord-006870-f5w6fw6q 1250 13 a a DT cord-006870-f5w6fw6q 1250 14 prospective prospective JJ cord-006870-f5w6fw6q 1250 15 observational observational JJ cord-006870-f5w6fw6q 1250 16 registry registry NN cord-006870-f5w6fw6q 1250 17 . . . cord-006870-f5w6fw6q 1251 1 Inclusion inclusion NN cord-006870-f5w6fw6q 1251 2 criteria criterion NNS cord-006870-f5w6fw6q 1251 3 included include VBD cord-006870-f5w6fw6q 1251 4 CTA CTA NNP cord-006870-f5w6fw6q 1251 5 obtained obtain VBD cord-006870-f5w6fw6q 1251 6 within within IN cord-006870-f5w6fw6q 1251 7 24 24 CD cord-006870-f5w6fw6q 1251 8 hours hour NNS cord-006870-f5w6fw6q 1251 9 of of IN cord-006870-f5w6fw6q 1251 10 symptoms symptom NNS cord-006870-f5w6fw6q 1251 11 onset onset NN cord-006870-f5w6fw6q 1251 12 and and CC cord-006870-f5w6fw6q 1251 13 admission admission NN cord-006870-f5w6fw6q 1251 14 magnesium magnesium NN cord-006870-f5w6fw6q 1251 15 and and CC cord-006870-f5w6fw6q 1251 16 calcium calcium NN cord-006870-f5w6fw6q 1251 17 levels level NNS cord-006870-f5w6fw6q 1251 18 . . . cord-006870-f5w6fw6q 1252 1 CTA CTA NNP cord-006870-f5w6fw6q 1252 2 spot spot NN cord-006870-f5w6fw6q 1252 3 sign sign NN cord-006870-f5w6fw6q 1252 4 ( ( -LRB- cord-006870-f5w6fw6q 1252 5 active active JJ cord-006870-f5w6fw6q 1252 6 contrast contrast NN cord-006870-f5w6fw6q 1252 7 extravasation extravasation NN cord-006870-f5w6fw6q 1252 8 on on IN cord-006870-f5w6fw6q 1252 9 CT CT NNP cord-006870-f5w6fw6q 1252 10 angiography angiography NN cord-006870-f5w6fw6q 1252 11 ) ) -RRB- cord-006870-f5w6fw6q 1252 12 was be VBD cord-006870-f5w6fw6q 1252 13 identified identify VBN cord-006870-f5w6fw6q 1252 14 by by IN cord-006870-f5w6fw6q 1252 15 a a DT cord-006870-f5w6fw6q 1252 16 board board NN cord-006870-f5w6fw6q 1252 17 - - HYPH cord-006870-f5w6fw6q 1252 18 certified certify VBN cord-006870-f5w6fw6q 1252 19 neurointensivist neurointensivist NN cord-006870-f5w6fw6q 1252 20 or or CC cord-006870-f5w6fw6q 1252 21 neuroradiologist neuroradiologist NNP cord-006870-f5w6fw6q 1252 22 . . . cord-006870-f5w6fw6q 1253 1 Variables variable NNS cord-006870-f5w6fw6q 1253 2 suggesting suggest VBG cord-006870-f5w6fw6q 1253 3 association association NN cord-006870-f5w6fw6q 1253 4 with with IN cord-006870-f5w6fw6q 1253 5 spot spot NN cord-006870-f5w6fw6q 1253 6 sign sign NN cord-006870-f5w6fw6q 1253 7 at at IN cord-006870-f5w6fw6q 1253 8 p<0.1 p<0.1 NNP cord-006870-f5w6fw6q 1253 9 were be VBD cord-006870-f5w6fw6q 1253 10 assessed assess VBN cord-006870-f5w6fw6q 1253 11 for for IN cord-006870-f5w6fw6q 1253 12 inclusion inclusion NN cord-006870-f5w6fw6q 1253 13 in in IN cord-006870-f5w6fw6q 1253 14 a a DT cord-006870-f5w6fw6q 1253 15 logistic logistic JJ cord-006870-f5w6fw6q 1253 16 regression regression NN cord-006870-f5w6fw6q 1253 17 model model NN cord-006870-f5w6fw6q 1253 18 , , , cord-006870-f5w6fw6q 1253 19 and and CC cord-006870-f5w6fw6q 1253 20 a a DT cord-006870-f5w6fw6q 1253 21 parsimonious parsimonious JJ cord-006870-f5w6fw6q 1253 22 predictive predictive JJ cord-006870-f5w6fw6q 1253 23 model model NN cord-006870-f5w6fw6q 1253 24 for for IN cord-006870-f5w6fw6q 1253 25 CT CT NNP cord-006870-f5w6fw6q 1253 26 spot spot NN cord-006870-f5w6fw6q 1253 27 sign sign NN cord-006870-f5w6fw6q 1253 28 was be VBD cord-006870-f5w6fw6q 1253 29 developed develop VBN cord-006870-f5w6fw6q 1253 30 using use VBG cord-006870-f5w6fw6q 1253 31 backward backward RB cord-006870-f5w6fw6q 1253 32 stepwise stepwise JJ cord-006870-f5w6fw6q 1253 33 variable variable JJ cord-006870-f5w6fw6q 1253 34 selection selection NN cord-006870-f5w6fw6q 1253 35 . . . cord-006870-f5w6fw6q 1254 1 146 146 CD cord-006870-f5w6fw6q 1254 2 patients patient NNS cord-006870-f5w6fw6q 1254 3 ( ( -LRB- cord-006870-f5w6fw6q 1254 4 age age NN cord-006870-f5w6fw6q 1254 5 63 63 CD cord-006870-f5w6fw6q 1254 6 ± ± CD cord-006870-f5w6fw6q 1254 7 14.5 14.5 CD cord-006870-f5w6fw6q 1254 8 years year NNS cord-006870-f5w6fw6q 1254 9 , , , cord-006870-f5w6fw6q 1254 10 47 47 CD cord-006870-f5w6fw6q 1254 11 % % NN cord-006870-f5w6fw6q 1254 12 male male NN cord-006870-f5w6fw6q 1254 13 , , , cord-006870-f5w6fw6q 1254 14 median median JJ cord-006870-f5w6fw6q 1254 15 ICH ICH NNP cord-006870-f5w6fw6q 1254 16 score score VBP cord-006870-f5w6fw6q 1254 17 1 1 CD cord-006870-f5w6fw6q 1254 18 [ [ -LRB- cord-006870-f5w6fw6q 1254 19 IQR IQR NNP cord-006870-f5w6fw6q 1254 20 1 1 CD cord-006870-f5w6fw6q 1254 21 - - SYM cord-006870-f5w6fw6q 1254 22 3 3 CD cord-006870-f5w6fw6q 1254 23 ] ] -RRB- cord-006870-f5w6fw6q 1254 24 ) ) -RRB- cord-006870-f5w6fw6q 1254 25 were be VBD cord-006870-f5w6fw6q 1254 26 included include VBN cord-006870-f5w6fw6q 1254 27 . . . cord-006870-f5w6fw6q 1255 1 Seventeen seventeen CD cord-006870-f5w6fw6q 1255 2 ( ( -LRB- cord-006870-f5w6fw6q 1255 3 11.6 11.6 CD cord-006870-f5w6fw6q 1255 4 % % NN cord-006870-f5w6fw6q 1255 5 ) ) -RRB- cord-006870-f5w6fw6q 1255 6 patients patient NNS cord-006870-f5w6fw6q 1255 7 with with IN cord-006870-f5w6fw6q 1255 8 CTA CTA NNP cord-006870-f5w6fw6q 1255 9 spot spot NN cord-006870-f5w6fw6q 1255 10 sign sign NN cord-006870-f5w6fw6q 1255 11 were be VBD cord-006870-f5w6fw6q 1255 12 identified identify VBN cord-006870-f5w6fw6q 1255 13 . . . cord-006870-f5w6fw6q 1256 1 Admission admission NN cord-006870-f5w6fw6q 1256 2 magnesium magnesium NN cord-006870-f5w6fw6q 1256 3 was be VBD cord-006870-f5w6fw6q 1256 4 1.96 1.96 CD cord-006870-f5w6fw6q 1256 5 + + CC cord-006870-f5w6fw6q 1257 1 /-0.27 /-0.27 NN cord-006870-f5w6fw6q 1257 2 and and CC cord-006870-f5w6fw6q 1257 3 calcium calcium NN cord-006870-f5w6fw6q 1257 4 was be VBD cord-006870-f5w6fw6q 1257 5 9.27 9.27 CD cord-006870-f5w6fw6q 1257 6 + + CC cord-006870-f5w6fw6q 1258 1 /-0.56 /-0.56 NNP cord-006870-f5w6fw6q 1258 2 . . . cord-006870-f5w6fw6q 1259 1 Lower low JJR cord-006870-f5w6fw6q 1259 2 magnesium magnesium NN cord-006870-f5w6fw6q 1259 3 ( ( -LRB- cord-006870-f5w6fw6q 1259 4 OR or NN cord-006870-f5w6fw6q 1259 5 0.074 0.074 CD cord-006870-f5w6fw6q 1259 6 , , , cord-006870-f5w6fw6q 1259 7 95 95 CD cord-006870-f5w6fw6q 1259 8 % % NN cord-006870-f5w6fw6q 1259 9 CI CI NNP cord-006870-f5w6fw6q 1259 10 0.007 0.007 CD cord-006870-f5w6fw6q 1259 11 - - HYPH cord-006870-f5w6fw6q 1259 12 0.746 0.746 CD cord-006870-f5w6fw6q 1259 13 , , , cord-006870-f5w6fw6q 1259 14 p p NN cord-006870-f5w6fw6q 1259 15 0.027 0.027 CD cord-006870-f5w6fw6q 1259 16 ) ) -RRB- cord-006870-f5w6fw6q 1259 17 , , , cord-006870-f5w6fw6q 1259 18 lower low JJR cord-006870-f5w6fw6q 1259 19 calcium calcium NN cord-006870-f5w6fw6q 1259 20 ( ( -LRB- cord-006870-f5w6fw6q 1259 21 OR OR NNP cord-006870-f5w6fw6q 1259 22 0.390 0.390 CD cord-006870-f5w6fw6q 1259 23 , , , cord-006870-f5w6fw6q 1259 24 95 95 CD cord-006870-f5w6fw6q 1259 25 % % NN cord-006870-f5w6fw6q 1259 26 CI CI NNP cord-006870-f5w6fw6q 1259 27 0.156 0.156 CD cord-006870-f5w6fw6q 1259 28 - - SYM cord-006870-f5w6fw6q 1259 29 0.973 0.973 CD cord-006870-f5w6fw6q 1259 30 , , , cord-006870-f5w6fw6q 1259 31 p p NN cord-006870-f5w6fw6q 1259 32 0.044 0.044 CD cord-006870-f5w6fw6q 1259 33 ) ) -RRB- cord-006870-f5w6fw6q 1259 34 , , , cord-006870-f5w6fw6q 1259 35 and and CC cord-006870-f5w6fw6q 1259 36 higher high JJR cord-006870-f5w6fw6q 1259 37 ICH ICH NNP cord-006870-f5w6fw6q 1259 38 Score Score NNP cord-006870-f5w6fw6q 1259 39 ( ( -LRB- cord-006870-f5w6fw6q 1259 40 OR or CC cord-006870-f5w6fw6q 1259 41 1.98 1.98 CD cord-006870-f5w6fw6q 1259 42 , , , cord-006870-f5w6fw6q 1259 43 95 95 CD cord-006870-f5w6fw6q 1259 44 % % NN cord-006870-f5w6fw6q 1259 45 CI CI NNP cord-006870-f5w6fw6q 1259 46 1.28 1.28 CD cord-006870-f5w6fw6q 1259 47 - - HYPH cord-006870-f5w6fw6q 1259 48 3.07 3.07 CD cord-006870-f5w6fw6q 1259 49 , , , cord-006870-f5w6fw6q 1259 50 p p NN cord-006870-f5w6fw6q 1259 51 0.002 0.002 CD cord-006870-f5w6fw6q 1259 52 ) ) -RRB- cord-006870-f5w6fw6q 1259 53 were be VBD cord-006870-f5w6fw6q 1259 54 independently independently RB cord-006870-f5w6fw6q 1259 55 associated associate VBN cord-006870-f5w6fw6q 1259 56 with with IN cord-006870-f5w6fw6q 1259 57 CT CT NNP cord-006870-f5w6fw6q 1259 58 spot spot NN cord-006870-f5w6fw6q 1259 59 sign sign NN cord-006870-f5w6fw6q 1259 60 . . . cord-006870-f5w6fw6q 1260 1 Magnesium magnesium NN cord-006870-f5w6fw6q 1260 2 and and CC cord-006870-f5w6fw6q 1260 3 calcium calcium NN cord-006870-f5w6fw6q 1260 4 level level NN cord-006870-f5w6fw6q 1260 5 on on IN cord-006870-f5w6fw6q 1260 6 admission admission NN cord-006870-f5w6fw6q 1260 7 are be VBP cord-006870-f5w6fw6q 1260 8 associated associate VBN cord-006870-f5w6fw6q 1260 9 with with IN cord-006870-f5w6fw6q 1260 10 the the DT cord-006870-f5w6fw6q 1260 11 presence presence NN cord-006870-f5w6fw6q 1260 12 of of IN cord-006870-f5w6fw6q 1260 13 a a DT cord-006870-f5w6fw6q 1260 14 CTA CTA NNP cord-006870-f5w6fw6q 1260 15 spot spot NN cord-006870-f5w6fw6q 1260 16 sign sign NN cord-006870-f5w6fw6q 1260 17 in in IN cord-006870-f5w6fw6q 1260 18 patients patient NNS cord-006870-f5w6fw6q 1260 19 with with IN cord-006870-f5w6fw6q 1260 20 ICH ICH NNP cord-006870-f5w6fw6q 1260 21 . . . cord-006870-f5w6fw6q 1261 1 Magnesium magnesium NN cord-006870-f5w6fw6q 1261 2 and and CC cord-006870-f5w6fw6q 1261 3 calcium calcium NN cord-006870-f5w6fw6q 1261 4 supplementation supplementation NN cord-006870-f5w6fw6q 1261 5 may may MD cord-006870-f5w6fw6q 1261 6 be be VB cord-006870-f5w6fw6q 1261 7 attractive attractive JJ cord-006870-f5w6fw6q 1261 8 therapeutic therapeutic JJ cord-006870-f5w6fw6q 1261 9 targets target NNS cord-006870-f5w6fw6q 1261 10 for for IN cord-006870-f5w6fw6q 1261 11 preventing prevent VBG cord-006870-f5w6fw6q 1261 12 harm harm NN cord-006870-f5w6fw6q 1261 13 from from IN cord-006870-f5w6fw6q 1261 14 hematoma hematoma NN cord-006870-f5w6fw6q 1261 15 growth growth NN cord-006870-f5w6fw6q 1261 16 . . . cord-006870-f5w6fw6q 1262 1 Cerebellar cerebellar JJ cord-006870-f5w6fw6q 1262 2 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 1262 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1262 4 ( ( -LRB- cord-006870-f5w6fw6q 1262 5 IPH IPH NNP cord-006870-f5w6fw6q 1262 6 ) ) -RRB- cord-006870-f5w6fw6q 1262 7 is be VBZ cord-006870-f5w6fw6q 1262 8 a a DT cord-006870-f5w6fw6q 1262 9 rare rare JJ cord-006870-f5w6fw6q 1262 10 and and CC cord-006870-f5w6fw6q 1262 11 likely likely JJ cord-006870-f5w6fw6q 1262 12 underreported underreported JJ cord-006870-f5w6fw6q 1262 13 complication complication NN cord-006870-f5w6fw6q 1262 14 of of IN cord-006870-f5w6fw6q 1262 15 subdural subdural JJ cord-006870-f5w6fw6q 1262 16 hematoma hematoma NN cord-006870-f5w6fw6q 1262 17 ( ( -LRB- cord-006870-f5w6fw6q 1262 18 SDH SDH NNP cord-006870-f5w6fw6q 1262 19 ) ) -RRB- cord-006870-f5w6fw6q 1262 20 evacuation evacuation NN cord-006870-f5w6fw6q 1262 21 . . . cord-006870-f5w6fw6q 1263 1 We -PRON- PRP cord-006870-f5w6fw6q 1263 2 present present VBP cord-006870-f5w6fw6q 1263 3 two two CD cord-006870-f5w6fw6q 1263 4 cases case NNS cord-006870-f5w6fw6q 1263 5 of of IN cord-006870-f5w6fw6q 1263 6 post post JJ cord-006870-f5w6fw6q 1263 7 - - JJ cord-006870-f5w6fw6q 1263 8 operative operative JJ cord-006870-f5w6fw6q 1263 9 IPH iph NN cord-006870-f5w6fw6q 1263 10 and and CC cord-006870-f5w6fw6q 1263 11 review review VB cord-006870-f5w6fw6q 1263 12 the the DT cord-006870-f5w6fw6q 1263 13 literature literature NN cord-006870-f5w6fw6q 1263 14 . . . cord-006870-f5w6fw6q 1264 1 Case case NN cord-006870-f5w6fw6q 1264 2 1 1 CD cord-006870-f5w6fw6q 1264 3 . . . cord-006870-f5w6fw6q 1265 1 An an DT cord-006870-f5w6fw6q 1265 2 83-year 83-year JJ cord-006870-f5w6fw6q 1265 3 - - HYPH cord-006870-f5w6fw6q 1265 4 old old JJ cord-006870-f5w6fw6q 1265 5 man man NN cord-006870-f5w6fw6q 1265 6 underwent undergo VBD cord-006870-f5w6fw6q 1265 7 craniotomy craniotomy NN cord-006870-f5w6fw6q 1265 8 for for IN cord-006870-f5w6fw6q 1265 9 evacuation evacuation NN cord-006870-f5w6fw6q 1265 10 of of IN cord-006870-f5w6fw6q 1265 11 a a DT cord-006870-f5w6fw6q 1265 12 chronic chronic JJ cord-006870-f5w6fw6q 1265 13 right right NN cord-006870-f5w6fw6q 1265 14 frontoparietal frontoparietal JJ cord-006870-f5w6fw6q 1265 15 SDH SDH NNP cord-006870-f5w6fw6q 1265 16 . . . cord-006870-f5w6fw6q 1266 1 Post post JJ cord-006870-f5w6fw6q 1266 2 - - JJ cord-006870-f5w6fw6q 1266 3 op op NNP cord-006870-f5w6fw6q 1266 4 CT CT NNP cord-006870-f5w6fw6q 1266 5 showed show VBD cord-006870-f5w6fw6q 1266 6 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 1266 7 . . . cord-006870-f5w6fw6q 1267 1 The the DT cord-006870-f5w6fw6q 1267 2 patient patient NN cord-006870-f5w6fw6q 1267 3 was be VBD cord-006870-f5w6fw6q 1267 4 extubated extubate VBN cord-006870-f5w6fw6q 1267 5 and and CC cord-006870-f5w6fw6q 1267 6 clinically clinically RB cord-006870-f5w6fw6q 1267 7 improved improve VBN cord-006870-f5w6fw6q 1267 8 . . . cord-006870-f5w6fw6q 1268 1 Three three CD cord-006870-f5w6fw6q 1268 2 days day NNS cord-006870-f5w6fw6q 1268 3 post post RB cord-006870-f5w6fw6q 1268 4 - - RB cord-006870-f5w6fw6q 1268 5 operatively operatively RB cord-006870-f5w6fw6q 1268 6 , , , cord-006870-f5w6fw6q 1268 7 he -PRON- PRP cord-006870-f5w6fw6q 1268 8 became become VBD cord-006870-f5w6fw6q 1268 9 lethargic lethargic JJ cord-006870-f5w6fw6q 1268 10 and and CC cord-006870-f5w6fw6q 1268 11 a a DT cord-006870-f5w6fw6q 1268 12 CT CT NNP cord-006870-f5w6fw6q 1268 13 brain brain NN cord-006870-f5w6fw6q 1268 14 revealed reveal VBD cord-006870-f5w6fw6q 1268 15 a a DT cord-006870-f5w6fw6q 1268 16 4cc 4cc CD cord-006870-f5w6fw6q 1268 17 right right JJ cord-006870-f5w6fw6q 1268 18 cerebellar cerebellar JJ cord-006870-f5w6fw6q 1268 19 IPH iph NN cord-006870-f5w6fw6q 1268 20 . . . cord-006870-f5w6fw6q 1269 1 He -PRON- PRP cord-006870-f5w6fw6q 1269 2 was be VBD cord-006870-f5w6fw6q 1269 3 unable unable JJ cord-006870-f5w6fw6q 1269 4 to to TO cord-006870-f5w6fw6q 1269 5 safely safely RB cord-006870-f5w6fw6q 1269 6 swallow swallow VB cord-006870-f5w6fw6q 1269 7 , , , cord-006870-f5w6fw6q 1269 8 declined decline VBD cord-006870-f5w6fw6q 1269 9 a a DT cord-006870-f5w6fw6q 1269 10 feeding feeding NN cord-006870-f5w6fw6q 1269 11 tube tube NN cord-006870-f5w6fw6q 1269 12 and and CC cord-006870-f5w6fw6q 1269 13 died die VBD cord-006870-f5w6fw6q 1269 14 under under IN cord-006870-f5w6fw6q 1269 15 hospice hospice NN cord-006870-f5w6fw6q 1269 16 care care NN cord-006870-f5w6fw6q 1269 17 nine nine CD cord-006870-f5w6fw6q 1269 18 days day NNS cord-006870-f5w6fw6q 1269 19 later later RB cord-006870-f5w6fw6q 1269 20 . . . cord-006870-f5w6fw6q 1270 1 Case case NN cord-006870-f5w6fw6q 1270 2 2 2 CD cord-006870-f5w6fw6q 1270 3 . . . cord-006870-f5w6fw6q 1271 1 A a DT cord-006870-f5w6fw6q 1271 2 72year 72year CD cord-006870-f5w6fw6q 1271 3 - - HYPH cord-006870-f5w6fw6q 1271 4 old old JJ cord-006870-f5w6fw6q 1271 5 man man NN cord-006870-f5w6fw6q 1271 6 underwent undergo VBD cord-006870-f5w6fw6q 1271 7 craniotomy craniotomy NN cord-006870-f5w6fw6q 1271 8 for for IN cord-006870-f5w6fw6q 1271 9 evacuation evacuation NN cord-006870-f5w6fw6q 1271 10 for for IN cord-006870-f5w6fw6q 1271 11 a a DT cord-006870-f5w6fw6q 1271 12 left left JJ cord-006870-f5w6fw6q 1271 13 convexity convexity NN cord-006870-f5w6fw6q 1271 14 SDH SDH NNP cord-006870-f5w6fw6q 1271 15 . . . cord-006870-f5w6fw6q 1272 1 Routine routine JJ cord-006870-f5w6fw6q 1272 2 post post JJ cord-006870-f5w6fw6q 1272 3 - - JJ cord-006870-f5w6fw6q 1272 4 op op JJ cord-006870-f5w6fw6q 1272 5 CT CT NNP cord-006870-f5w6fw6q 1272 6 revealed reveal VBD cord-006870-f5w6fw6q 1272 7 an an DT cord-006870-f5w6fw6q 1272 8 incidental incidental JJ cord-006870-f5w6fw6q 1272 9 left left JJ cord-006870-f5w6fw6q 1272 10 cerebellar cerebellar JJ cord-006870-f5w6fw6q 1272 11 IPH iph NN cord-006870-f5w6fw6q 1272 12 . . . cord-006870-f5w6fw6q 1273 1 He -PRON- PRP cord-006870-f5w6fw6q 1273 2 returned return VBD cord-006870-f5w6fw6q 1273 3 to to IN cord-006870-f5w6fw6q 1273 4 baseline baseline VB cord-006870-f5w6fw6q 1273 5 one one CD cord-006870-f5w6fw6q 1273 6 month month NN cord-006870-f5w6fw6q 1273 7 later later RB cord-006870-f5w6fw6q 1273 8 . . . cord-006870-f5w6fw6q 1274 1 Only only RB cord-006870-f5w6fw6q 1274 2 four four CD cord-006870-f5w6fw6q 1274 3 such such JJ cord-006870-f5w6fw6q 1274 4 cases case NNS cord-006870-f5w6fw6q 1274 5 have have VBP cord-006870-f5w6fw6q 1274 6 been be VBN cord-006870-f5w6fw6q 1274 7 reported report VBN cord-006870-f5w6fw6q 1274 8 in in IN cord-006870-f5w6fw6q 1274 9 the the DT cord-006870-f5w6fw6q 1274 10 literature literature NN cord-006870-f5w6fw6q 1274 11 ( ( -LRB- cord-006870-f5w6fw6q 1274 12 1 1 CD cord-006870-f5w6fw6q 1274 13 - - SYM cord-006870-f5w6fw6q 1274 14 4 4 CD cord-006870-f5w6fw6q 1274 15 ) ) -RRB- cord-006870-f5w6fw6q 1274 16 . . . cord-006870-f5w6fw6q 1275 1 Two two CD cord-006870-f5w6fw6q 1275 2 cases case NNS cord-006870-f5w6fw6q 1275 3 led lead VBD cord-006870-f5w6fw6q 1275 4 to to IN cord-006870-f5w6fw6q 1275 5 death death NN cord-006870-f5w6fw6q 1275 6 within within IN cord-006870-f5w6fw6q 1275 7 one one CD cord-006870-f5w6fw6q 1275 8 week week NN cord-006870-f5w6fw6q 1275 9 and and CC cord-006870-f5w6fw6q 1275 10 two two CD cord-006870-f5w6fw6q 1275 11 recovered recover VBD cord-006870-f5w6fw6q 1275 12 , , , cord-006870-f5w6fw6q 1275 13 one one CD cord-006870-f5w6fw6q 1275 14 with with IN cord-006870-f5w6fw6q 1275 15 significant significant JJ cord-006870-f5w6fw6q 1275 16 deficits deficit NNS cord-006870-f5w6fw6q 1275 17 . . . cord-006870-f5w6fw6q 1276 1 Five five CD cord-006870-f5w6fw6q 1276 2 more more JJR cord-006870-f5w6fw6q 1276 3 occurred occur VBD cord-006870-f5w6fw6q 1276 4 following follow VBG cord-006870-f5w6fw6q 1276 5 burr burr NNP cord-006870-f5w6fw6q 1276 6 hole hole NN cord-006870-f5w6fw6q 1276 7 drainage drainage NN cord-006870-f5w6fw6q 1276 8 of of IN cord-006870-f5w6fw6q 1276 9 SDH SDH NNP cord-006870-f5w6fw6q 1276 10 and and CC cord-006870-f5w6fw6q 1276 11 two two CD cord-006870-f5w6fw6q 1276 12 others other NNS cord-006870-f5w6fw6q 1276 13 following follow VBG cord-006870-f5w6fw6q 1276 14 drainage drainage NN cord-006870-f5w6fw6q 1276 15 of of IN cord-006870-f5w6fw6q 1276 16 subdural subdural JJ cord-006870-f5w6fw6q 1276 17 hygromas hygromas NNPS cord-006870-f5w6fw6q 1276 18 ( ( -LRB- cord-006870-f5w6fw6q 1276 19 2 2 CD cord-006870-f5w6fw6q 1276 20 , , , cord-006870-f5w6fw6q 1276 21 5 5 CD cord-006870-f5w6fw6q 1276 22 - - SYM cord-006870-f5w6fw6q 1276 23 10 10 CD cord-006870-f5w6fw6q 1276 24 ) ) -RRB- cord-006870-f5w6fw6q 1276 25 . . . cord-006870-f5w6fw6q 1277 1 The the DT cord-006870-f5w6fw6q 1277 2 incidence incidence NN cord-006870-f5w6fw6q 1277 3 of of IN cord-006870-f5w6fw6q 1277 4 cerebellar cerebellar JJ cord-006870-f5w6fw6q 1277 5 IPH iph NN cord-006870-f5w6fw6q 1277 6 following follow VBG cord-006870-f5w6fw6q 1277 7 supratentorial supratentorial JJ cord-006870-f5w6fw6q 1277 8 craniotomy craniotomy NN cord-006870-f5w6fw6q 1277 9 has have VBZ cord-006870-f5w6fw6q 1277 10 been be VBN cord-006870-f5w6fw6q 1277 11 reported report VBN cord-006870-f5w6fw6q 1277 12 in in IN cord-006870-f5w6fw6q 1277 13 up up IN cord-006870-f5w6fw6q 1277 14 to to TO cord-006870-f5w6fw6q 1277 15 0.29 0.29 CD cord-006870-f5w6fw6q 1277 16 % % NN cord-006870-f5w6fw6q 1277 17 of of IN cord-006870-f5w6fw6q 1277 18 cases case NNS cord-006870-f5w6fw6q 1277 19 with with IN cord-006870-f5w6fw6q 1277 20 significant significant JJ cord-006870-f5w6fw6q 1277 21 morbidity morbidity NN cord-006870-f5w6fw6q 1277 22 or or CC cord-006870-f5w6fw6q 1277 23 mortality mortality NN cord-006870-f5w6fw6q 1277 24 ( ( -LRB- cord-006870-f5w6fw6q 1277 25 3 3 CD cord-006870-f5w6fw6q 1277 26 ) ) -RRB- cord-006870-f5w6fw6q 1277 27 . . . cord-006870-f5w6fw6q 1278 1 It -PRON- PRP cord-006870-f5w6fw6q 1278 2 occurs occur VBZ cord-006870-f5w6fw6q 1278 3 irrespective irrespective RB cord-006870-f5w6fw6q 1278 4 of of IN cord-006870-f5w6fw6q 1278 5 age age NN cord-006870-f5w6fw6q 1278 6 , , , cord-006870-f5w6fw6q 1278 7 pre pre JJ cord-006870-f5w6fw6q 1278 8 - - JJ cord-006870-f5w6fw6q 1278 9 existing existing JJ cord-006870-f5w6fw6q 1278 10 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 1278 11 or or CC cord-006870-f5w6fw6q 1278 12 arteriovenous arteriovenous JJ cord-006870-f5w6fw6q 1278 13 malformations malformation NNS cord-006870-f5w6fw6q 1278 14 . . . cord-006870-f5w6fw6q 1279 1 Size size NN cord-006870-f5w6fw6q 1279 2 of of IN cord-006870-f5w6fw6q 1279 3 insult insult NN cord-006870-f5w6fw6q 1279 4 and and CC cord-006870-f5w6fw6q 1279 5 amount amount NN cord-006870-f5w6fw6q 1279 6 of of IN cord-006870-f5w6fw6q 1279 7 CSF CSF NNP cord-006870-f5w6fw6q 1279 8 loss loss NN cord-006870-f5w6fw6q 1279 9 do do VBP cord-006870-f5w6fw6q 1279 10 not not RB cord-006870-f5w6fw6q 1279 11 correlate correlate VB cord-006870-f5w6fw6q 1279 12 to to IN cord-006870-f5w6fw6q 1279 13 IPH IPH NNP cord-006870-f5w6fw6q 1279 14 , , , cord-006870-f5w6fw6q 1279 15 despite despite IN cord-006870-f5w6fw6q 1279 16 the the DT cord-006870-f5w6fw6q 1279 17 fact fact NN cord-006870-f5w6fw6q 1279 18 that that IN cord-006870-f5w6fw6q 1279 19 cerebral cerebral JJ cord-006870-f5w6fw6q 1279 20 blood blood NN cord-006870-f5w6fw6q 1279 21 flow flow NN cord-006870-f5w6fw6q 1279 22 imaging imaging NN cord-006870-f5w6fw6q 1279 23 shows show VBZ cord-006870-f5w6fw6q 1279 24 over over IN cord-006870-f5w6fw6q 1279 25 - - HYPH cord-006870-f5w6fw6q 1279 26 drainage drainage NN cord-006870-f5w6fw6q 1279 27 of of IN cord-006870-f5w6fw6q 1279 28 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 1279 29 fluid fluid NN cord-006870-f5w6fw6q 1279 30 ( ( -LRB- cord-006870-f5w6fw6q 1279 31 CSF CSF NNP cord-006870-f5w6fw6q 1279 32 ) ) -RRB- cord-006870-f5w6fw6q 1279 33 , , , cord-006870-f5w6fw6q 1279 34 causes cause VBZ cord-006870-f5w6fw6q 1279 35 intracranial intracranial JJ cord-006870-f5w6fw6q 1279 36 hypotension hypotension NN cord-006870-f5w6fw6q 1279 37 and and CC cord-006870-f5w6fw6q 1279 38 subsequent subsequent JJ cord-006870-f5w6fw6q 1279 39 damage damage NN cord-006870-f5w6fw6q 1279 40 to to IN cord-006870-f5w6fw6q 1279 41 dural dural JJ cord-006870-f5w6fw6q 1279 42 veins vein NNS cord-006870-f5w6fw6q 1279 43 ( ( -LRB- cord-006870-f5w6fw6q 1279 44 3,11 3,11 CD cord-006870-f5w6fw6q 1279 45 ) ) -RRB- cord-006870-f5w6fw6q 1279 46 . . . cord-006870-f5w6fw6q 1280 1 IPH IPH NNP cord-006870-f5w6fw6q 1280 2 also also RB cord-006870-f5w6fw6q 1280 3 occurs occur VBZ cord-006870-f5w6fw6q 1280 4 independently independently RB cord-006870-f5w6fw6q 1280 5 of of IN cord-006870-f5w6fw6q 1280 6 operating operate VBG cord-006870-f5w6fw6q 1280 7 room room NN cord-006870-f5w6fw6q 1280 8 position position NN cord-006870-f5w6fw6q 1280 9 , , , cord-006870-f5w6fw6q 1280 10 even even RB cord-006870-f5w6fw6q 1280 11 though though IN cord-006870-f5w6fw6q 1280 12 having have VBG cord-006870-f5w6fw6q 1280 13 the the DT cord-006870-f5w6fw6q 1280 14 head head NN cord-006870-f5w6fw6q 1280 15 turned turn VBN cord-006870-f5w6fw6q 1280 16 is be VBZ cord-006870-f5w6fw6q 1280 17 thought think VBN cord-006870-f5w6fw6q 1280 18 to to TO cord-006870-f5w6fw6q 1280 19 compress compress VB cord-006870-f5w6fw6q 1280 20 venous venous JJ cord-006870-f5w6fw6q 1280 21 drainage drainage NN cord-006870-f5w6fw6q 1280 22 in in IN cord-006870-f5w6fw6q 1280 23 the the DT cord-006870-f5w6fw6q 1280 24 neck neck NN cord-006870-f5w6fw6q 1280 25 and and CC cord-006870-f5w6fw6q 1280 26 cause cause VB cord-006870-f5w6fw6q 1280 27 congestion congestion NN cord-006870-f5w6fw6q 1280 28 ( ( -LRB- cord-006870-f5w6fw6q 1280 29 3 3 CD cord-006870-f5w6fw6q 1280 30 ) ) -RRB- cord-006870-f5w6fw6q 1280 31 . . . cord-006870-f5w6fw6q 1281 1 Cerebellar cerebellar JJ cord-006870-f5w6fw6q 1281 2 vasculature vasculature NN cord-006870-f5w6fw6q 1281 3 may may MD cord-006870-f5w6fw6q 1281 4 be be VB cord-006870-f5w6fw6q 1281 5 more more RBR cord-006870-f5w6fw6q 1281 6 sensitive sensitive JJ cord-006870-f5w6fw6q 1281 7 to to IN cord-006870-f5w6fw6q 1281 8 changes change NNS cord-006870-f5w6fw6q 1281 9 in in IN cord-006870-f5w6fw6q 1281 10 intracranial intracranial JJ cord-006870-f5w6fw6q 1281 11 pressure pressure NN cord-006870-f5w6fw6q 1281 12 , , , cord-006870-f5w6fw6q 1281 13 though though IN cord-006870-f5w6fw6q 1281 14 why why WRB cord-006870-f5w6fw6q 1281 15 this this DT cord-006870-f5w6fw6q 1281 16 does do VBZ cord-006870-f5w6fw6q 1281 17 not not RB cord-006870-f5w6fw6q 1281 18 lead lead VB cord-006870-f5w6fw6q 1281 19 to to IN cord-006870-f5w6fw6q 1281 20 complications complication NNS cord-006870-f5w6fw6q 1281 21 more more RBR cord-006870-f5w6fw6q 1281 22 routinely routinely RB cord-006870-f5w6fw6q 1281 23 is be VBZ cord-006870-f5w6fw6q 1281 24 not not RB cord-006870-f5w6fw6q 1281 25 clear clear JJ cord-006870-f5w6fw6q 1281 26 . . . cord-006870-f5w6fw6q 1282 1 Cerebellar cerebellar JJ cord-006870-f5w6fw6q 1282 2 IPH iph NN cord-006870-f5w6fw6q 1282 3 should should MD cord-006870-f5w6fw6q 1282 4 be be VB cord-006870-f5w6fw6q 1282 5 considered consider VBN cord-006870-f5w6fw6q 1282 6 in in IN cord-006870-f5w6fw6q 1282 7 cases case NNS cord-006870-f5w6fw6q 1282 8 of of IN cord-006870-f5w6fw6q 1282 9 neurological neurological JJ cord-006870-f5w6fw6q 1282 10 decline decline NN cord-006870-f5w6fw6q 1282 11 after after IN cord-006870-f5w6fw6q 1282 12 SDH SDH NNP cord-006870-f5w6fw6q 1282 13 evacuation evacuation NN cord-006870-f5w6fw6q 1282 14 . . . cord-006870-f5w6fw6q 1283 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1283 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1283 3 ( ( -LRB- cord-006870-f5w6fw6q 1283 4 ICH ICH NNP cord-006870-f5w6fw6q 1283 5 ) ) -RRB- cord-006870-f5w6fw6q 1283 6 location location NN cord-006870-f5w6fw6q 1283 7 predicts predict VBZ cord-006870-f5w6fw6q 1283 8 outcome outcome NN cord-006870-f5w6fw6q 1283 9 , , , cord-006870-f5w6fw6q 1283 10 but but CC cord-006870-f5w6fw6q 1283 11 most most JJS cord-006870-f5w6fw6q 1283 12 studies study NNS cord-006870-f5w6fw6q 1283 13 have have VBP cord-006870-f5w6fw6q 1283 14 examined examine VBN cord-006870-f5w6fw6q 1283 15 differences difference NNS cord-006870-f5w6fw6q 1283 16 between between IN cord-006870-f5w6fw6q 1283 17 deep deep JJ cord-006870-f5w6fw6q 1283 18 , , , cord-006870-f5w6fw6q 1283 19 lobar lobar JJ cord-006870-f5w6fw6q 1283 20 , , , cord-006870-f5w6fw6q 1283 21 and and CC cord-006870-f5w6fw6q 1283 22 infratentorial infratentorial JJ cord-006870-f5w6fw6q 1283 23 locations location NNS cord-006870-f5w6fw6q 1283 24 . . . cord-006870-f5w6fw6q 1284 1 This this DT cord-006870-f5w6fw6q 1284 2 study study NN cord-006870-f5w6fw6q 1284 3 aims aim VBZ cord-006870-f5w6fw6q 1284 4 to to TO cord-006870-f5w6fw6q 1284 5 characterize characterize VB cord-006870-f5w6fw6q 1284 6 specific specific JJ cord-006870-f5w6fw6q 1284 7 deep deep JJ cord-006870-f5w6fw6q 1284 8 ICH ICH NNP cord-006870-f5w6fw6q 1284 9 locations location NNS cord-006870-f5w6fw6q 1284 10 in in IN cord-006870-f5w6fw6q 1284 11 a a DT cord-006870-f5w6fw6q 1284 12 diverse diverse JJ cord-006870-f5w6fw6q 1284 13 cohort cohort NN cord-006870-f5w6fw6q 1284 14 . . . cord-006870-f5w6fw6q 1285 1 The the DT cord-006870-f5w6fw6q 1285 2 Ethnic ethnic JJ cord-006870-f5w6fw6q 1285 3 / / SYM cord-006870-f5w6fw6q 1285 4 Racial Racial NNP cord-006870-f5w6fw6q 1285 5 Variations Variations NNPS cord-006870-f5w6fw6q 1285 6 of of IN cord-006870-f5w6fw6q 1285 7 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1285 8 Hemorrhage Hemorrhage NNP cord-006870-f5w6fw6q 1285 9 ( ( -LRB- cord-006870-f5w6fw6q 1285 10 ERICH ERICH NNP cord-006870-f5w6fw6q 1285 11 ) ) -RRB- cord-006870-f5w6fw6q 1285 12 study study NN cord-006870-f5w6fw6q 1285 13 is be VBZ cord-006870-f5w6fw6q 1285 14 a a DT cord-006870-f5w6fw6q 1285 15 multi multi JJ cord-006870-f5w6fw6q 1285 16 - - JJ cord-006870-f5w6fw6q 1285 17 center center JJ cord-006870-f5w6fw6q 1285 18 , , , cord-006870-f5w6fw6q 1285 19 prospective prospective JJ cord-006870-f5w6fw6q 1285 20 , , , cord-006870-f5w6fw6q 1285 21 U.S.-based u.s.-based JJ cord-006870-f5w6fw6q 1285 22 study study NN cord-006870-f5w6fw6q 1285 23 . . . cord-006870-f5w6fw6q 1286 1 1345 1345 CD cord-006870-f5w6fw6q 1286 2 subjects subject NNS cord-006870-f5w6fw6q 1286 3 with with IN cord-006870-f5w6fw6q 1286 4 supratentorial supratentorial NNP cord-006870-f5w6fw6q 1286 5 deep deep JJ cord-006870-f5w6fw6q 1286 6 ICH ICH NNP cord-006870-f5w6fw6q 1286 7 , , , cord-006870-f5w6fw6q 1286 8 known know VBN cord-006870-f5w6fw6q 1286 9 ICH ICH NNP cord-006870-f5w6fw6q 1286 10 volume volume NN cord-006870-f5w6fw6q 1286 11 , , , cord-006870-f5w6fw6q 1286 12 and and CC cord-006870-f5w6fw6q 1286 13 three three CD cord-006870-f5w6fw6q 1286 14 - - HYPH cord-006870-f5w6fw6q 1286 15 month month NN cord-006870-f5w6fw6q 1286 16 follow follow NN cord-006870-f5w6fw6q 1286 17 - - HYPH cord-006870-f5w6fw6q 1286 18 up up RP cord-006870-f5w6fw6q 1286 19 data datum NNS cord-006870-f5w6fw6q 1286 20 were be VBD cord-006870-f5w6fw6q 1286 21 included include VBN cord-006870-f5w6fw6q 1286 22 . . . cord-006870-f5w6fw6q 1287 1 Logistic logistic JJ cord-006870-f5w6fw6q 1287 2 regression regression NN cord-006870-f5w6fw6q 1287 3 was be VBD cord-006870-f5w6fw6q 1287 4 used use VBN cord-006870-f5w6fw6q 1287 5 to to TO cord-006870-f5w6fw6q 1287 6 evaluate evaluate VB cord-006870-f5w6fw6q 1287 7 the the DT cord-006870-f5w6fw6q 1287 8 association association NN cord-006870-f5w6fw6q 1287 9 between between IN cord-006870-f5w6fw6q 1287 10 location location NN cord-006870-f5w6fw6q 1287 11 and and CC cord-006870-f5w6fw6q 1287 12 poor poor JJ cord-006870-f5w6fw6q 1287 13 outcome outcome NN cord-006870-f5w6fw6q 1288 1 ( ( -LRB- cord-006870-f5w6fw6q 1288 2 mRS mrs VB cord-006870-f5w6fw6q 1288 3 > > XX cord-006870-f5w6fw6q 1288 4 3 3 CD cord-006870-f5w6fw6q 1288 5 ) ) -RRB- cord-006870-f5w6fw6q 1288 6 . . . cord-006870-f5w6fw6q 1289 1 Receiver receiver NN cord-006870-f5w6fw6q 1289 2 operating operating NN cord-006870-f5w6fw6q 1289 3 curve curve NN cord-006870-f5w6fw6q 1289 4 ( ( -LRB- cord-006870-f5w6fw6q 1289 5 ROC ROC NNP cord-006870-f5w6fw6q 1289 6 ) ) -RRB- cord-006870-f5w6fw6q 1289 7 analysis analysis NN cord-006870-f5w6fw6q 1289 8 was be VBD cord-006870-f5w6fw6q 1289 9 performed perform VBN cord-006870-f5w6fw6q 1289 10 to to TO cord-006870-f5w6fw6q 1289 11 identify identify VB cord-006870-f5w6fw6q 1289 12 ICH ICH NNP cord-006870-f5w6fw6q 1289 13 volumes volume NNS cord-006870-f5w6fw6q 1289 14 specific specific JJ cord-006870-f5w6fw6q 1289 15 for for IN cord-006870-f5w6fw6q 1289 16 poor poor JJ cord-006870-f5w6fw6q 1289 17 outcome outcome NN cord-006870-f5w6fw6q 1289 18 by by IN cord-006870-f5w6fw6q 1289 19 location location NN cord-006870-f5w6fw6q 1289 20 . . . cord-006870-f5w6fw6q 1290 1 671 671 CD cord-006870-f5w6fw6q 1290 2 thalamic thalamic JJ cord-006870-f5w6fw6q 1290 3 , , , cord-006870-f5w6fw6q 1290 4 581 581 CD cord-006870-f5w6fw6q 1290 5 putaminal putaminal NN cord-006870-f5w6fw6q 1290 6 , , , cord-006870-f5w6fw6q 1290 7 and and CC cord-006870-f5w6fw6q 1290 8 83 83 CD cord-006870-f5w6fw6q 1290 9 caudate caudate NN cord-006870-f5w6fw6q 1290 10 ICHs ICHs NNPS cord-006870-f5w6fw6q 1290 11 were be VBD cord-006870-f5w6fw6q 1290 12 included include VBN cord-006870-f5w6fw6q 1290 13 . . . cord-006870-f5w6fw6q 1291 1 Median median JJ cord-006870-f5w6fw6q 1291 2 ICH ICH NNP cord-006870-f5w6fw6q 1291 3 volume volume NN cord-006870-f5w6fw6q 1291 4 was be VBD cord-006870-f5w6fw6q 1291 5 largest large JJS cord-006870-f5w6fw6q 1291 6 in in IN cord-006870-f5w6fw6q 1291 7 putamen putaman NNS cord-006870-f5w6fw6q 1291 8 ( ( -LRB- cord-006870-f5w6fw6q 1291 9 15 15 CD cord-006870-f5w6fw6q 1291 10 mL ml NN cord-006870-f5w6fw6q 1291 11 ) ) -RRB- cord-006870-f5w6fw6q 1291 12 , , , cord-006870-f5w6fw6q 1291 13 followed follow VBN cord-006870-f5w6fw6q 1291 14 by by IN cord-006870-f5w6fw6q 1291 15 thalamus thalamus NNP cord-006870-f5w6fw6q 1291 16 ( ( -LRB- cord-006870-f5w6fw6q 1291 17 9 9 CD cord-006870-f5w6fw6q 1291 18 mL ml NN cord-006870-f5w6fw6q 1291 19 ) ) -RRB- cord-006870-f5w6fw6q 1291 20 and and CC cord-006870-f5w6fw6q 1291 21 caudate caudate NNP cord-006870-f5w6fw6q 1291 22 ( ( -LRB- cord-006870-f5w6fw6q 1291 23 4 4 CD cord-006870-f5w6fw6q 1291 24 mL ml NN cord-006870-f5w6fw6q 1291 25 , , , cord-006870-f5w6fw6q 1291 26 p<.001 p<.001 JJ cord-006870-f5w6fw6q 1291 27 ) ) -RRB- cord-006870-f5w6fw6q 1291 28 . . . cord-006870-f5w6fw6q 1292 1 Intraventricular intraventricular JJ cord-006870-f5w6fw6q 1292 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1292 3 ( ( -LRB- cord-006870-f5w6fw6q 1292 4 IVH IVH NNP cord-006870-f5w6fw6q 1292 5 ) ) -RRB- cord-006870-f5w6fw6q 1292 6 was be VBD cord-006870-f5w6fw6q 1292 7 most most RBS cord-006870-f5w6fw6q 1292 8 prevalent prevalent JJ cord-006870-f5w6fw6q 1292 9 in in IN cord-006870-f5w6fw6q 1292 10 caudate caudate NNP cord-006870-f5w6fw6q 1292 11 ( ( -LRB- cord-006870-f5w6fw6q 1292 12 94 94 CD cord-006870-f5w6fw6q 1292 13 % % NN cord-006870-f5w6fw6q 1292 14 ) ) -RRB- cord-006870-f5w6fw6q 1292 15 , , , cord-006870-f5w6fw6q 1292 16 followed follow VBN cord-006870-f5w6fw6q 1292 17 by by IN cord-006870-f5w6fw6q 1292 18 thalamus thalamus NNP cord-006870-f5w6fw6q 1292 19 ( ( -LRB- cord-006870-f5w6fw6q 1292 20 65 65 CD cord-006870-f5w6fw6q 1292 21 % % NN cord-006870-f5w6fw6q 1292 22 ) ) -RRB- cord-006870-f5w6fw6q 1292 23 and and CC cord-006870-f5w6fw6q 1292 24 putamen putaman NNS cord-006870-f5w6fw6q 1292 25 ( ( -LRB- cord-006870-f5w6fw6q 1292 26 23 23 CD cord-006870-f5w6fw6q 1292 27 % % NN cord-006870-f5w6fw6q 1292 28 , , , cord-006870-f5w6fw6q 1292 29 p p NN cord-006870-f5w6fw6q 1292 30 < < XX cord-006870-f5w6fw6q 1292 31 0.001 0.001 CD cord-006870-f5w6fw6q 1292 32 ) ) -RRB- cord-006870-f5w6fw6q 1292 33 . . . cord-006870-f5w6fw6q 1293 1 Subjects subject NNS cord-006870-f5w6fw6q 1293 2 with with IN cord-006870-f5w6fw6q 1293 3 thalamic thalamic JJ cord-006870-f5w6fw6q 1293 4 ICH ICH NNP cord-006870-f5w6fw6q 1293 5 were be VBD cord-006870-f5w6fw6q 1293 6 older old JJR cord-006870-f5w6fw6q 1293 7 ( ( -LRB- cord-006870-f5w6fw6q 1293 8 62 62 CD cord-006870-f5w6fw6q 1293 9 vs vs IN cord-006870-f5w6fw6q 1293 10 57 57 CD cord-006870-f5w6fw6q 1293 11 vs vs IN cord-006870-f5w6fw6q 1293 12 58 58 CD cord-006870-f5w6fw6q 1293 13 years year NNS cord-006870-f5w6fw6q 1293 14 , , , cord-006870-f5w6fw6q 1293 15 p p NN cord-006870-f5w6fw6q 1293 16 < < XX cord-006870-f5w6fw6q 1293 17 0.001 0.001 CD cord-006870-f5w6fw6q 1293 18 ) ) -RRB- cord-006870-f5w6fw6q 1293 19 and and CC cord-006870-f5w6fw6q 1293 20 more more RBR cord-006870-f5w6fw6q 1293 21 likely likely JJ cord-006870-f5w6fw6q 1293 22 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1293 23 ( ( -LRB- cord-006870-f5w6fw6q 1293 24 91 91 CD cord-006870-f5w6fw6q 1293 25 % % NN cord-006870-f5w6fw6q 1293 26 vs vs IN cord-006870-f5w6fw6q 1293 27 85 85 CD cord-006870-f5w6fw6q 1293 28 % % NN cord-006870-f5w6fw6q 1293 29 vs vs IN cord-006870-f5w6fw6q 1293 30 82 82 CD cord-006870-f5w6fw6q 1293 31 % % NN cord-006870-f5w6fw6q 1293 32 , , , cord-006870-f5w6fw6q 1293 33 p= p= NNP cord-006870-f5w6fw6q 1293 34 0.002 0.002 CD cord-006870-f5w6fw6q 1293 35 ) ) -RRB- cord-006870-f5w6fw6q 1293 36 than than IN cord-006870-f5w6fw6q 1293 37 those those DT cord-006870-f5w6fw6q 1293 38 with with IN cord-006870-f5w6fw6q 1293 39 putaminal putaminal JJ cord-006870-f5w6fw6q 1293 40 and and CC cord-006870-f5w6fw6q 1293 41 caudate caudate NNP cord-006870-f5w6fw6q 1293 42 ICH ICH NNP cord-006870-f5w6fw6q 1293 43 , , , cord-006870-f5w6fw6q 1293 44 respectively respectively RB cord-006870-f5w6fw6q 1293 45 . . . cord-006870-f5w6fw6q 1294 1 Compared compare VBN cord-006870-f5w6fw6q 1294 2 to to IN cord-006870-f5w6fw6q 1294 3 thalamic thalamic JJ cord-006870-f5w6fw6q 1294 4 , , , cord-006870-f5w6fw6q 1294 5 putaminal putaminal JJ cord-006870-f5w6fw6q 1294 6 ICH ICH NNP cord-006870-f5w6fw6q 1294 7 had have VBD cord-006870-f5w6fw6q 1294 8 more more JJR cord-006870-f5w6fw6q 1294 9 ICH ICH NNP cord-006870-f5w6fw6q 1294 10 expansion expansion NN cord-006870-f5w6fw6q 1294 11 ( ( -LRB- cord-006870-f5w6fw6q 1294 12 23 23 CD cord-006870-f5w6fw6q 1294 13 % % NN cord-006870-f5w6fw6q 1294 14 vs vs IN cord-006870-f5w6fw6q 1294 15 15 15 CD cord-006870-f5w6fw6q 1294 16 % % NN cord-006870-f5w6fw6q 1294 17 , , , cord-006870-f5w6fw6q 1294 18 p p NN cord-006870-f5w6fw6q 1294 19 < < XX cord-006870-f5w6fw6q 1294 20 0.001 0.001 CD cord-006870-f5w6fw6q 1294 21 ) ) -RRB- cord-006870-f5w6fw6q 1294 22 and and CC cord-006870-f5w6fw6q 1294 23 surgery surgery NN cord-006870-f5w6fw6q 1294 24 ( ( -LRB- cord-006870-f5w6fw6q 1294 25 20 20 CD cord-006870-f5w6fw6q 1294 26 % % NN cord-006870-f5w6fw6q 1294 27 vs vs IN cord-006870-f5w6fw6q 1294 28 14 14 CD cord-006870-f5w6fw6q 1294 29 % % NN cord-006870-f5w6fw6q 1294 30 p p NN cord-006870-f5w6fw6q 1294 31 = = SYM cord-006870-f5w6fw6q 1294 32 0.004 0.004 CD cord-006870-f5w6fw6q 1294 33 ) ) -RRB- cord-006870-f5w6fw6q 1295 1 but but CC cord-006870-f5w6fw6q 1295 2 fewer few JJR cord-006870-f5w6fw6q 1295 3 external external JJ cord-006870-f5w6fw6q 1295 4 ventricular ventricular JJ cord-006870-f5w6fw6q 1295 5 drains drain NNS cord-006870-f5w6fw6q 1295 6 ( ( -LRB- cord-006870-f5w6fw6q 1295 7 15 15 CD cord-006870-f5w6fw6q 1295 8 % % NN cord-006870-f5w6fw6q 1295 9 vs vs IN cord-006870-f5w6fw6q 1295 10 27 27 CD cord-006870-f5w6fw6q 1295 11 % % NN cord-006870-f5w6fw6q 1295 12 , , , cord-006870-f5w6fw6q 1295 13 p p NN cord-006870-f5w6fw6q 1295 14 < < XX cord-006870-f5w6fw6q 1295 15 0.001 0.001 CD cord-006870-f5w6fw6q 1295 16 ) ) -RRB- cord-006870-f5w6fw6q 1295 17 . . . cord-006870-f5w6fw6q 1296 1 Thalamic thalamic JJ cord-006870-f5w6fw6q 1296 2 location location NN cord-006870-f5w6fw6q 1296 3 predicted predict VBD cord-006870-f5w6fw6q 1296 4 poor poor JJ cord-006870-f5w6fw6q 1296 5 outcome outcome NN cord-006870-f5w6fw6q 1296 6 ( ( -LRB- cord-006870-f5w6fw6q 1296 7 OR or CC cord-006870-f5w6fw6q 1296 8 2.25 2.25 CD cord-006870-f5w6fw6q 1296 9 , , , cord-006870-f5w6fw6q 1297 1 95 95 CD cord-006870-f5w6fw6q 1297 2 % % NN cord-006870-f5w6fw6q 1297 3 CI CI NNP cord-006870-f5w6fw6q 1297 4 1.35 1.35 CD cord-006870-f5w6fw6q 1297 5 - - HYPH cord-006870-f5w6fw6q 1297 6 3.73 3.73 CD cord-006870-f5w6fw6q 1297 7 ) ) -RRB- cord-006870-f5w6fw6q 1297 8 at at IN cord-006870-f5w6fw6q 1297 9 90 90 CD cord-006870-f5w6fw6q 1297 10 days day NNS cord-006870-f5w6fw6q 1297 11 after after IN cord-006870-f5w6fw6q 1297 12 adjustment adjustment NN cord-006870-f5w6fw6q 1297 13 for for IN cord-006870-f5w6fw6q 1297 14 age age NN cord-006870-f5w6fw6q 1297 15 , , , cord-006870-f5w6fw6q 1297 16 sex sex NN cord-006870-f5w6fw6q 1297 17 , , , cord-006870-f5w6fw6q 1297 18 premorbid premorbid NN cord-006870-f5w6fw6q 1297 19 disability disability NN cord-006870-f5w6fw6q 1297 20 , , , cord-006870-f5w6fw6q 1297 21 ICH ICH NNP cord-006870-f5w6fw6q 1297 22 volume volume NN cord-006870-f5w6fw6q 1297 23 , , , cord-006870-f5w6fw6q 1297 24 ICH ICH NNP cord-006870-f5w6fw6q 1297 25 expansion expansion NN cord-006870-f5w6fw6q 1297 26 , , , cord-006870-f5w6fw6q 1297 27 IVH IVH NNP cord-006870-f5w6fw6q 1297 28 , , , cord-006870-f5w6fw6q 1297 29 and and CC cord-006870-f5w6fw6q 1297 30 admission admission NN cord-006870-f5w6fw6q 1297 31 GCS GCS NNP cord-006870-f5w6fw6q 1297 32 . . . cord-006870-f5w6fw6q 1298 1 ROC ROC NNP cord-006870-f5w6fw6q 1298 2 analysis analysis NN cord-006870-f5w6fw6q 1298 3 identified identify VBD cord-006870-f5w6fw6q 1298 4 10 10 CD cord-006870-f5w6fw6q 1298 5 mL ml NN cord-006870-f5w6fw6q 1298 6 for for IN cord-006870-f5w6fw6q 1298 7 thalamic thalamic JJ cord-006870-f5w6fw6q 1298 8 and and CC cord-006870-f5w6fw6q 1298 9 29 29 CD cord-006870-f5w6fw6q 1298 10 mL ml NN cord-006870-f5w6fw6q 1298 11 for for IN cord-006870-f5w6fw6q 1298 12 putaminal putaminal JJ cord-006870-f5w6fw6q 1298 13 ICH ICH NNP cord-006870-f5w6fw6q 1298 14 without without IN cord-006870-f5w6fw6q 1298 15 IVH IVH NNP cord-006870-f5w6fw6q 1298 16 as as IN cord-006870-f5w6fw6q 1298 17 having have VBG cord-006870-f5w6fw6q 1298 18 95 95 CD cord-006870-f5w6fw6q 1298 19 % % NN cord-006870-f5w6fw6q 1298 20 specificity specificity NN cord-006870-f5w6fw6q 1298 21 for for IN cord-006870-f5w6fw6q 1298 22 poor poor JJ cord-006870-f5w6fw6q 1298 23 outcome outcome NN cord-006870-f5w6fw6q 1298 24 . . . cord-006870-f5w6fw6q 1299 1 There there EX cord-006870-f5w6fw6q 1299 2 are be VBP cord-006870-f5w6fw6q 1299 3 significant significant JJ cord-006870-f5w6fw6q 1299 4 differences difference NNS cord-006870-f5w6fw6q 1299 5 in in IN cord-006870-f5w6fw6q 1299 6 characteristics characteristic NNS cord-006870-f5w6fw6q 1299 7 and and CC cord-006870-f5w6fw6q 1299 8 outcomes outcome NNS cord-006870-f5w6fw6q 1299 9 within within IN cord-006870-f5w6fw6q 1299 10 deep deep JJ cord-006870-f5w6fw6q 1299 11 ICH ICH NNP cord-006870-f5w6fw6q 1299 12 . . . cord-006870-f5w6fw6q 1300 1 Specificity specificity NN cord-006870-f5w6fw6q 1300 2 estimates estimate NNS cord-006870-f5w6fw6q 1300 3 for for IN cord-006870-f5w6fw6q 1300 4 the the DT cord-006870-f5w6fw6q 1300 5 identified identify VBN cord-006870-f5w6fw6q 1300 6 ICH ICH NNP cord-006870-f5w6fw6q 1300 7 volume volume NN cord-006870-f5w6fw6q 1300 8 thresholds threshold NNS cord-006870-f5w6fw6q 1300 9 require require VBP cord-006870-f5w6fw6q 1300 10 external external JJ cord-006870-f5w6fw6q 1300 11 validation validation NN cord-006870-f5w6fw6q 1300 12 . . . cord-006870-f5w6fw6q 1301 1 These these DT cord-006870-f5w6fw6q 1301 2 findings finding NNS cord-006870-f5w6fw6q 1301 3 may may MD cord-006870-f5w6fw6q 1301 4 have have VB cord-006870-f5w6fw6q 1301 5 implications implication NNS cord-006870-f5w6fw6q 1301 6 for for IN cord-006870-f5w6fw6q 1301 7 prognostication prognostication NN cord-006870-f5w6fw6q 1301 8 and and CC cord-006870-f5w6fw6q 1301 9 clinical clinical JJ cord-006870-f5w6fw6q 1301 10 trial trial NN cord-006870-f5w6fw6q 1301 11 design design NN cord-006870-f5w6fw6q 1301 12 . . . cord-006870-f5w6fw6q 1302 1 Racial racial JJ cord-006870-f5w6fw6q 1302 2 differences difference NNS cord-006870-f5w6fw6q 1302 3 in in IN cord-006870-f5w6fw6q 1302 4 outcome outcome NN cord-006870-f5w6fw6q 1302 5 after after IN cord-006870-f5w6fw6q 1302 6 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1302 7 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1302 8 ( ( -LRB- cord-006870-f5w6fw6q 1302 9 ICH ICH NNP cord-006870-f5w6fw6q 1302 10 ) ) -RRB- cord-006870-f5w6fw6q 1302 11 among among IN cord-006870-f5w6fw6q 1302 12 Asians Asians NNPS cord-006870-f5w6fw6q 1302 13 , , , cord-006870-f5w6fw6q 1302 14 Native native JJ cord-006870-f5w6fw6q 1302 15 Hawaiians Hawaiians NNPS cord-006870-f5w6fw6q 1302 16 and and CC cord-006870-f5w6fw6q 1302 17 other other JJ cord-006870-f5w6fw6q 1302 18 Pacific Pacific NNP cord-006870-f5w6fw6q 1302 19 Islanders Islanders NNPS cord-006870-f5w6fw6q 1302 20 ( ( -LRB- cord-006870-f5w6fw6q 1302 21 NHOPI NHOPI NNPS cord-006870-f5w6fw6q 1302 22 ) ) -RRB- cord-006870-f5w6fw6q 1302 23 have have VBP cord-006870-f5w6fw6q 1302 24 been be VBN cord-006870-f5w6fw6q 1302 25 inadequately inadequately RB cord-006870-f5w6fw6q 1302 26 studied study VBN cord-006870-f5w6fw6q 1302 27 since since IN cord-006870-f5w6fw6q 1302 28 these these DT cord-006870-f5w6fw6q 1302 29 racial racial JJ cord-006870-f5w6fw6q 1302 30 groups group NNS cord-006870-f5w6fw6q 1302 31 have have VBP cord-006870-f5w6fw6q 1302 32 been be VBN cord-006870-f5w6fw6q 1302 33 historically historically RB cord-006870-f5w6fw6q 1302 34 aggregated aggregate VBN cord-006870-f5w6fw6q 1302 35 into into IN cord-006870-f5w6fw6q 1302 36 a a DT cord-006870-f5w6fw6q 1302 37 single single JJ cord-006870-f5w6fw6q 1302 38 racial racial JJ cord-006870-f5w6fw6q 1302 39 category category NN cord-006870-f5w6fw6q 1302 40 . . . cord-006870-f5w6fw6q 1303 1 A a DT cord-006870-f5w6fw6q 1303 2 multiracial multiracial JJ cord-006870-f5w6fw6q 1303 3 prospective prospective JJ cord-006870-f5w6fw6q 1303 4 cohort cohort NN cord-006870-f5w6fw6q 1303 5 study study NN cord-006870-f5w6fw6q 1303 6 of of IN cord-006870-f5w6fw6q 1303 7 ICH ICH NNP cord-006870-f5w6fw6q 1303 8 patients patient NNS cord-006870-f5w6fw6q 1303 9 was be VBD cord-006870-f5w6fw6q 1303 10 conducted conduct VBN cord-006870-f5w6fw6q 1303 11 from from IN cord-006870-f5w6fw6q 1303 12 2011 2011 CD cord-006870-f5w6fw6q 1303 13 to to IN cord-006870-f5w6fw6q 1303 14 2016 2016 CD cord-006870-f5w6fw6q 1303 15 at at IN cord-006870-f5w6fw6q 1303 16 a a DT cord-006870-f5w6fw6q 1303 17 tertiary tertiary JJ cord-006870-f5w6fw6q 1303 18 center center NN cord-006870-f5w6fw6q 1303 19 in in IN cord-006870-f5w6fw6q 1303 20 Honolulu Honolulu NNP cord-006870-f5w6fw6q 1303 21 , , , cord-006870-f5w6fw6q 1303 22 HI HI NNP cord-006870-f5w6fw6q 1303 23 to to TO cord-006870-f5w6fw6q 1303 24 assess assess VB cord-006870-f5w6fw6q 1303 25 racial racial JJ cord-006870-f5w6fw6q 1303 26 disparities disparity NNS cord-006870-f5w6fw6q 1303 27 in in IN cord-006870-f5w6fw6q 1303 28 come come NN cord-006870-f5w6fw6q 1303 29 after after IN cord-006870-f5w6fw6q 1303 30 ICH ICH NNP cord-006870-f5w6fw6q 1303 31 . . . cord-006870-f5w6fw6q 1304 1 Favorable favorable JJ cord-006870-f5w6fw6q 1304 2 outcome outcome NN cord-006870-f5w6fw6q 1304 3 was be VBD cord-006870-f5w6fw6q 1304 4 defined define VBN cord-006870-f5w6fw6q 1304 5 as as IN cord-006870-f5w6fw6q 1304 6 3month 3month NN cord-006870-f5w6fw6q 1304 7 modified modify VBN cord-006870-f5w6fw6q 1304 8 Rankin Rankin NNP cord-006870-f5w6fw6q 1304 9 Scale Scale NNP cord-006870-f5w6fw6q 1304 10 ( ( -LRB- cord-006870-f5w6fw6q 1304 11 mRS mRS : cord-006870-f5w6fw6q 1304 12 ) ) -RRB- cord-006870-f5w6fw6q 1304 13 score score VB cord-006870-f5w6fw6q 1304 14 £ £ $ cord-006870-f5w6fw6q 1304 15 2 2 CD cord-006870-f5w6fw6q 1304 16 . . . cord-006870-f5w6fw6q 1305 1 Patients patient NNS cord-006870-f5w6fw6q 1305 2 with with IN cord-006870-f5w6fw6q 1305 3 no no DT cord-006870-f5w6fw6q 1305 4 available available JJ cord-006870-f5w6fw6q 1305 5 3-month 3-month CD cord-006870-f5w6fw6q 1305 6 functional functional JJ cord-006870-f5w6fw6q 1305 7 outcome outcome NN cord-006870-f5w6fw6q 1305 8 , , , cord-006870-f5w6fw6q 1305 9 race race NN cord-006870-f5w6fw6q 1305 10 other other JJ cord-006870-f5w6fw6q 1305 11 than than IN cord-006870-f5w6fw6q 1305 12 Asians Asians NNPS cord-006870-f5w6fw6q 1305 13 and and CC cord-006870-f5w6fw6q 1305 14 NHOPI NHOPI NNPS cord-006870-f5w6fw6q 1305 15 , , , cord-006870-f5w6fw6q 1305 16 and and CC cord-006870-f5w6fw6q 1305 17 baseline baseline JJ cord-006870-f5w6fw6q 1305 18 mRS mrs XX cord-006870-f5w6fw6q 1305 19 > > XX cord-006870-f5w6fw6q 1305 20 0 0 NFP cord-006870-f5w6fw6q 1305 21 were be VBD cord-006870-f5w6fw6q 1305 22 excluded exclude VBN cord-006870-f5w6fw6q 1305 23 . . . cord-006870-f5w6fw6q 1306 1 Multivariable multivariable JJ cord-006870-f5w6fw6q 1306 2 analyses analysis NNS cord-006870-f5w6fw6q 1306 3 using use VBG cord-006870-f5w6fw6q 1306 4 logistic logistic JJ cord-006870-f5w6fw6q 1306 5 regression regression NN cord-006870-f5w6fw6q 1306 6 were be VBD cord-006870-f5w6fw6q 1306 7 performed perform VBN cord-006870-f5w6fw6q 1306 8 to to TO cord-006870-f5w6fw6q 1306 9 assess assess VB cord-006870-f5w6fw6q 1306 10 the the DT cord-006870-f5w6fw6q 1306 11 impact impact NN cord-006870-f5w6fw6q 1306 12 of of IN cord-006870-f5w6fw6q 1306 13 race race NN cord-006870-f5w6fw6q 1306 14 on on IN cord-006870-f5w6fw6q 1306 15 favorable favorable JJ cord-006870-f5w6fw6q 1306 16 outcome outcome NN cord-006870-f5w6fw6q 1306 17 after after IN cord-006870-f5w6fw6q 1306 18 adjusting adjust VBG cord-006870-f5w6fw6q 1306 19 for for IN cord-006870-f5w6fw6q 1306 20 the the DT cord-006870-f5w6fw6q 1306 21 ICH ICH NNP cord-006870-f5w6fw6q 1306 22 Score Score NNP cord-006870-f5w6fw6q 1306 23 , , , cord-006870-f5w6fw6q 1306 24 early early RB cord-006870-f5w6fw6q 1306 25 do do VB cord-006870-f5w6fw6q 1306 26 - - HYPH cord-006870-f5w6fw6q 1306 27 not not RB cord-006870-f5w6fw6q 1306 28 - - HYPH cord-006870-f5w6fw6q 1306 29 resuscitate resuscitate VB cord-006870-f5w6fw6q 1306 30 ( ( -LRB- cord-006870-f5w6fw6q 1306 31 DNR DNR NNP cord-006870-f5w6fw6q 1306 32 ) ) -RRB- cord-006870-f5w6fw6q 1306 33 order order NN cord-006870-f5w6fw6q 1306 34 and and CC cord-006870-f5w6fw6q 1306 35 dementia dementia NN cord-006870-f5w6fw6q 1306 36 / / SYM cord-006870-f5w6fw6q 1306 37 cognitive cognitive JJ cord-006870-f5w6fw6q 1306 38 impairment impairment NN cord-006870-f5w6fw6q 1306 39 . . . cord-006870-f5w6fw6q 1307 1 A a DT cord-006870-f5w6fw6q 1307 2 total total NN cord-006870-f5w6fw6q 1307 3 of of IN cord-006870-f5w6fw6q 1307 4 220 220 CD cord-006870-f5w6fw6q 1307 5 patients patient NNS cord-006870-f5w6fw6q 1307 6 ( ( -LRB- cord-006870-f5w6fw6q 1307 7 161 161 CD cord-006870-f5w6fw6q 1307 8 Asians Asians NNPS cord-006870-f5w6fw6q 1307 9 , , , cord-006870-f5w6fw6q 1307 10 59 59 CD cord-006870-f5w6fw6q 1307 11 NHOPI NHOPI NNPS cord-006870-f5w6fw6q 1307 12 ) ) -RRB- cord-006870-f5w6fw6q 1307 13 were be VBD cord-006870-f5w6fw6q 1307 14 studied study VBN cord-006870-f5w6fw6q 1307 15 . . . cord-006870-f5w6fw6q 1308 1 Overall overall RB cord-006870-f5w6fw6q 1308 2 , , , cord-006870-f5w6fw6q 1308 3 65 65 CD cord-006870-f5w6fw6q 1308 4 ( ( -LRB- cord-006870-f5w6fw6q 1308 5 29.5 29.5 CD cord-006870-f5w6fw6q 1308 6 % % NN cord-006870-f5w6fw6q 1308 7 ) ) -RRB- cord-006870-f5w6fw6q 1308 8 achieved achieve VBD cord-006870-f5w6fw6q 1308 9 favorable favorable JJ cord-006870-f5w6fw6q 1308 10 outcome outcome NN cord-006870-f5w6fw6q 1308 11 at at IN cord-006870-f5w6fw6q 1308 12 3 3 CD cord-006870-f5w6fw6q 1308 13 months month NNS cord-006870-f5w6fw6q 1308 14 . . . cord-006870-f5w6fw6q 1309 1 NHOPI NHOPI NNPS cord-006870-f5w6fw6q 1309 2 were be VBD cord-006870-f5w6fw6q 1309 3 younger young JJR cord-006870-f5w6fw6q 1309 4 than than IN cord-006870-f5w6fw6q 1309 5 Asians Asians NNPS cord-006870-f5w6fw6q 1309 6 ( ( -LRB- cord-006870-f5w6fw6q 1309 7 51.8±15.3 51.8±15.3 CD cord-006870-f5w6fw6q 1309 8 vs. vs. IN cord-006870-f5w6fw6q 1309 9 63.9±16.7 63.9±16.7 CD cord-006870-f5w6fw6q 1309 10 years year NNS cord-006870-f5w6fw6q 1309 11 respectively respectively RB cord-006870-f5w6fw6q 1309 12 , , , cord-006870-f5w6fw6q 1309 13 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 1309 14 ) ) -RRB- cord-006870-f5w6fw6q 1309 15 , , , cord-006870-f5w6fw6q 1309 16 and and CC cord-006870-f5w6fw6q 1309 17 had have VBD cord-006870-f5w6fw6q 1309 18 higher high JJR cord-006870-f5w6fw6q 1309 19 prevalence prevalence NN cord-006870-f5w6fw6q 1309 20 of of IN cord-006870-f5w6fw6q 1309 21 diabetes diabete NNS cord-006870-f5w6fw6q 1309 22 ( ( -LRB- cord-006870-f5w6fw6q 1309 23 39.0 39.0 CD cord-006870-f5w6fw6q 1309 24 % % NN cord-006870-f5w6fw6q 1309 25 vs. vs. CC cord-006870-f5w6fw6q 1309 26 21.1 21.1 CD cord-006870-f5w6fw6q 1309 27 % % NN cord-006870-f5w6fw6q 1309 28 respectively respectively RB cord-006870-f5w6fw6q 1309 29 , , , cord-006870-f5w6fw6q 1309 30 p=0.007 p=0.007 NNP cord-006870-f5w6fw6q 1309 31 ) ) -RRB- cord-006870-f5w6fw6q 1309 32 , , , cord-006870-f5w6fw6q 1309 33 obesity obesity NN cord-006870-f5w6fw6q 1309 34 ( ( -LRB- cord-006870-f5w6fw6q 1309 35 58.9 58.9 CD cord-006870-f5w6fw6q 1309 36 % % NN cord-006870-f5w6fw6q 1309 37 vs. vs. CC cord-006870-f5w6fw6q 1309 38 23.1 23.1 CD cord-006870-f5w6fw6q 1309 39 respectively respectively RB cord-006870-f5w6fw6q 1309 40 , , , cord-006870-f5w6fw6q 1309 41 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 1309 42 ) ) -RRB- cord-006870-f5w6fw6q 1309 43 , , , cord-006870-f5w6fw6q 1309 44 and and CC cord-006870-f5w6fw6q 1309 45 lower low JJR cord-006870-f5w6fw6q 1309 46 prevalence prevalence NN cord-006870-f5w6fw6q 1309 47 of of IN cord-006870-f5w6fw6q 1309 48 early early JJ cord-006870-f5w6fw6q 1309 49 DNR DNR NNP cord-006870-f5w6fw6q 1309 50 order order NN cord-006870-f5w6fw6q 1309 51 ( ( -LRB- cord-006870-f5w6fw6q 1309 52 3.4 3.4 CD cord-006870-f5w6fw6q 1309 53 % % NN cord-006870-f5w6fw6q 1309 54 vs. vs. CC cord-006870-f5w6fw6q 1309 55 24.2 24.2 CD cord-006870-f5w6fw6q 1309 56 % % NN cord-006870-f5w6fw6q 1309 57 respectively respectively RB cord-006870-f5w6fw6q 1309 58 , , , cord-006870-f5w6fw6q 1309 59 p=0.0004 p=0.0004 NN cord-006870-f5w6fw6q 1309 60 ) ) -RRB- cord-006870-f5w6fw6q 1309 61 and and CC cord-006870-f5w6fw6q 1309 62 advance advance NN cord-006870-f5w6fw6q 1309 63 directive directive NN cord-006870-f5w6fw6q 1309 64 presence presence NN cord-006870-f5w6fw6q 1309 65 ( ( -LRB- cord-006870-f5w6fw6q 1309 66 6.8 6.8 CD cord-006870-f5w6fw6q 1309 67 % % NN cord-006870-f5w6fw6q 1309 68 vs. vs. CC cord-006870-f5w6fw6q 1309 69 29.2 29.2 CD cord-006870-f5w6fw6q 1309 70 % % NN cord-006870-f5w6fw6q 1309 71 respectively respectively RB cord-006870-f5w6fw6q 1309 72 , , , cord-006870-f5w6fw6q 1309 73 p=0.0005 p=0.0005 NNP cord-006870-f5w6fw6q 1309 74 ) ) -RRB- cord-006870-f5w6fw6q 1309 75 . . . cord-006870-f5w6fw6q 1310 1 NHOPI nhopi JJ cord-006870-f5w6fw6q 1310 2 race race NN cord-006870-f5w6fw6q 1310 3 was be VBD cord-006870-f5w6fw6q 1310 4 a a DT cord-006870-f5w6fw6q 1310 5 predictor predictor NN cord-006870-f5w6fw6q 1310 6 of of IN cord-006870-f5w6fw6q 1310 7 favorable favorable JJ cord-006870-f5w6fw6q 1310 8 outcome outcome NN cord-006870-f5w6fw6q 1310 9 in in IN cord-006870-f5w6fw6q 1310 10 the the DT cord-006870-f5w6fw6q 1310 11 unadjusted unadjusted JJ cord-006870-f5w6fw6q 1310 12 model model NN cord-006870-f5w6fw6q 1310 13 ( ( -LRB- cord-006870-f5w6fw6q 1310 14 OR or CC cord-006870-f5w6fw6q 1310 15 2.47 2.47 CD cord-006870-f5w6fw6q 1310 16 , , , cord-006870-f5w6fw6q 1310 17 95 95 CD cord-006870-f5w6fw6q 1310 18 % % NN cord-006870-f5w6fw6q 1310 19 CI ci NN cord-006870-f5w6fw6q 1310 20 : : : cord-006870-f5w6fw6q 1310 21 1.32 1.32 CD cord-006870-f5w6fw6q 1310 22 , , , cord-006870-f5w6fw6q 1310 23 4.62 4.62 CD cord-006870-f5w6fw6q 1310 24 ) ) -RRB- cord-006870-f5w6fw6q 1310 25 and and CC cord-006870-f5w6fw6q 1310 26 after after IN cord-006870-f5w6fw6q 1310 27 adjusting adjust VBG cord-006870-f5w6fw6q 1310 28 for for IN cord-006870-f5w6fw6q 1310 29 the the DT cord-006870-f5w6fw6q 1310 30 ICH ICH NNP cord-006870-f5w6fw6q 1310 31 Score Score NNP cord-006870-f5w6fw6q 1310 32 ( ( -LRB- cord-006870-f5w6fw6q 1310 33 OR or CC cord-006870-f5w6fw6q 1310 34 2.30 2.30 CD cord-006870-f5w6fw6q 1311 1 , , , cord-006870-f5w6fw6q 1311 2 95 95 CD cord-006870-f5w6fw6q 1311 3 % % NN cord-006870-f5w6fw6q 1311 4 CI ci NN cord-006870-f5w6fw6q 1311 5 : : : cord-006870-f5w6fw6q 1311 6 1.06 1.06 CD cord-006870-f5w6fw6q 1311 7 , , , cord-006870-f5w6fw6q 1311 8 4.97 4.97 CD cord-006870-f5w6fw6q 1311 9 ) ) -RRB- cord-006870-f5w6fw6q 1311 10 but but CC cord-006870-f5w6fw6q 1312 1 not not RB cord-006870-f5w6fw6q 1312 2 in in IN cord-006870-f5w6fw6q 1312 3 the the DT cord-006870-f5w6fw6q 1312 4 final final JJ cord-006870-f5w6fw6q 1312 5 model model NN cord-006870-f5w6fw6q 1312 6 ( ( -LRB- cord-006870-f5w6fw6q 1312 7 OR or CC cord-006870-f5w6fw6q 1312 8 2.04 2.04 CD cord-006870-f5w6fw6q 1312 9 , , , cord-006870-f5w6fw6q 1312 10 95 95 CD cord-006870-f5w6fw6q 1312 11 % % NN cord-006870-f5w6fw6q 1312 12 CI ci NN cord-006870-f5w6fw6q 1312 13 : : : cord-006870-f5w6fw6q 1312 14 0.94 0.94 CD cord-006870-f5w6fw6q 1312 15 , , , cord-006870-f5w6fw6q 1312 16 4.42 4.42 CD cord-006870-f5w6fw6q 1312 17 ) ) -RRB- cord-006870-f5w6fw6q 1312 18 . . . cord-006870-f5w6fw6q 1313 1 In in IN cord-006870-f5w6fw6q 1313 2 the the DT cord-006870-f5w6fw6q 1313 3 final final JJ cord-006870-f5w6fw6q 1313 4 model model NN cord-006870-f5w6fw6q 1313 5 , , , cord-006870-f5w6fw6q 1313 6 the the DT cord-006870-f5w6fw6q 1313 7 ICH ICH NNP cord-006870-f5w6fw6q 1313 8 Score Score NNP cord-006870-f5w6fw6q 1313 9 remained remain VBD cord-006870-f5w6fw6q 1313 10 as as IN cord-006870-f5w6fw6q 1313 11 the the DT cord-006870-f5w6fw6q 1313 12 only only JJ cord-006870-f5w6fw6q 1313 13 independent independent JJ cord-006870-f5w6fw6q 1313 14 negative negative JJ cord-006870-f5w6fw6q 1313 15 predictor predictor NN cord-006870-f5w6fw6q 1313 16 of of IN cord-006870-f5w6fw6q 1313 17 outcome outcome NN cord-006870-f5w6fw6q 1313 18 ( ( -LRB- cord-006870-f5w6fw6q 1313 19 OR or CC cord-006870-f5w6fw6q 1313 20 0.26 0.26 CD cord-006870-f5w6fw6q 1313 21 , , . cord-006870-f5w6fw6q 1314 1 95 95 CD cord-006870-f5w6fw6q 1314 2 % % NN cord-006870-f5w6fw6q 1314 3 CI ci NN cord-006870-f5w6fw6q 1314 4 : : : cord-006870-f5w6fw6q 1315 1 0.17 0.17 CD cord-006870-f5w6fw6q 1315 2 , , , cord-006870-f5w6fw6q 1315 3 0.41 0.41 CD cord-006870-f5w6fw6q 1315 4 per per IN cord-006870-f5w6fw6q 1315 5 point point NN cord-006870-f5w6fw6q 1315 6 ) ) -RRB- cord-006870-f5w6fw6q 1315 7 . . . cord-006870-f5w6fw6q 1316 1 NHOPI NHOPI NNS cord-006870-f5w6fw6q 1316 2 are be VBP cord-006870-f5w6fw6q 1316 3 more more RBR cord-006870-f5w6fw6q 1316 4 likely likely JJ cord-006870-f5w6fw6q 1316 5 to to TO cord-006870-f5w6fw6q 1316 6 achieve achieve VB cord-006870-f5w6fw6q 1316 7 favorable favorable JJ cord-006870-f5w6fw6q 1316 8 functional functional JJ cord-006870-f5w6fw6q 1316 9 outcome outcome NN cord-006870-f5w6fw6q 1316 10 after after IN cord-006870-f5w6fw6q 1316 11 ICH ICH NNP cord-006870-f5w6fw6q 1316 12 compared compare VBD cord-006870-f5w6fw6q 1316 13 to to IN cord-006870-f5w6fw6q 1316 14 Asians Asians NNPS cord-006870-f5w6fw6q 1316 15 even even RB cord-006870-f5w6fw6q 1316 16 after after IN cord-006870-f5w6fw6q 1316 17 controlling control VBG cord-006870-f5w6fw6q 1316 18 for for IN cord-006870-f5w6fw6q 1316 19 ICH ICH NNP cord-006870-f5w6fw6q 1316 20 severity severity NN cord-006870-f5w6fw6q 1316 21 . . . cord-006870-f5w6fw6q 1317 1 However however RB cord-006870-f5w6fw6q 1317 2 , , , cord-006870-f5w6fw6q 1317 3 this this DT cord-006870-f5w6fw6q 1317 4 association association NN cord-006870-f5w6fw6q 1317 5 was be VBD cord-006870-f5w6fw6q 1317 6 attenuated attenuate VBN cord-006870-f5w6fw6q 1317 7 after after IN cord-006870-f5w6fw6q 1317 8 adjusting adjust VBG cord-006870-f5w6fw6q 1317 9 for for IN cord-006870-f5w6fw6q 1317 10 DNR DNR NNP cord-006870-f5w6fw6q 1317 11 status status NN cord-006870-f5w6fw6q 1317 12 and and CC cord-006870-f5w6fw6q 1317 13 baseline baseline JJ cord-006870-f5w6fw6q 1317 14 cognitive cognitive JJ cord-006870-f5w6fw6q 1317 15 factors factor NNS cord-006870-f5w6fw6q 1317 16 . . . cord-006870-f5w6fw6q 1318 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1318 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1319 1 ( ( -LRB- cord-006870-f5w6fw6q 1319 2 ICH ICH NNP cord-006870-f5w6fw6q 1319 3 ) ) -RRB- cord-006870-f5w6fw6q 1319 4 patients patient NNS cord-006870-f5w6fw6q 1319 5 often often RB cord-006870-f5w6fw6q 1319 6 require require VBP cord-006870-f5w6fw6q 1319 7 continuous continuous JJ cord-006870-f5w6fw6q 1319 8 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1319 9 infusions infusion NNS cord-006870-f5w6fw6q 1319 10 . . . cord-006870-f5w6fw6q 1320 1 We -PRON- PRP cord-006870-f5w6fw6q 1320 2 sought seek VBD cord-006870-f5w6fw6q 1320 3 to to TO cord-006870-f5w6fw6q 1320 4 identify identify VB cord-006870-f5w6fw6q 1320 5 clinical clinical JJ cord-006870-f5w6fw6q 1320 6 and and CC cord-006870-f5w6fw6q 1320 7 care care NN cord-006870-f5w6fw6q 1320 8 process process NN cord-006870-f5w6fw6q 1320 9 predictors predictor NNS cord-006870-f5w6fw6q 1320 10 of of IN cord-006870-f5w6fw6q 1320 11 anti anti JJ cord-006870-f5w6fw6q 1320 12 - - JJ cord-006870-f5w6fw6q 1320 13 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1320 14 infusion infusion NN cord-006870-f5w6fw6q 1320 15 duration duration NN cord-006870-f5w6fw6q 1320 16 , , , cord-006870-f5w6fw6q 1320 17 and and CC cord-006870-f5w6fw6q 1320 18 tested test VBD cord-006870-f5w6fw6q 1320 19 whether whether IN cord-006870-f5w6fw6q 1320 20 infusion infusion NN cord-006870-f5w6fw6q 1320 21 duration duration NN cord-006870-f5w6fw6q 1320 22 independently independently RB cord-006870-f5w6fw6q 1320 23 predicts predict VBZ cord-006870-f5w6fw6q 1320 24 intensive intensive JJ cord-006870-f5w6fw6q 1320 25 care care NN cord-006870-f5w6fw6q 1320 26 unit unit NN cord-006870-f5w6fw6q 1320 27 length length NN cord-006870-f5w6fw6q 1320 28 of of IN cord-006870-f5w6fw6q 1320 29 stay stay NN cord-006870-f5w6fw6q 1320 30 ( ( -LRB- cord-006870-f5w6fw6q 1320 31 ICU ICU NNP cord-006870-f5w6fw6q 1320 32 LOS LOS NNP cord-006870-f5w6fw6q 1320 33 ) ) -RRB- cord-006870-f5w6fw6q 1320 34 after after IN cord-006870-f5w6fw6q 1320 35 adjusting adjust VBG cord-006870-f5w6fw6q 1320 36 for for IN cord-006870-f5w6fw6q 1320 37 validated validate VBN cord-006870-f5w6fw6q 1320 38 measures measure NNS cord-006870-f5w6fw6q 1320 39 of of IN cord-006870-f5w6fw6q 1320 40 ICH ICH NNP cord-006870-f5w6fw6q 1320 41 illness illness NN cord-006870-f5w6fw6q 1320 42 severity severity NN cord-006870-f5w6fw6q 1320 43 . . . cord-006870-f5w6fw6q 1321 1 We -PRON- PRP cord-006870-f5w6fw6q 1321 2 identified identify VBD cord-006870-f5w6fw6q 1321 3 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1321 4 ICH ICH NNP cord-006870-f5w6fw6q 1321 5 patients patient NNS cord-006870-f5w6fw6q 1321 6 admitted admit VBD cord-006870-f5w6fw6q 1321 7 12/2013 12/2013 CD cord-006870-f5w6fw6q 1321 8 - - HYPH cord-006870-f5w6fw6q 1321 9 9/2015 9/2015 CD cord-006870-f5w6fw6q 1321 10 to to IN cord-006870-f5w6fw6q 1321 11 a a DT cord-006870-f5w6fw6q 1321 12 tertiary tertiary JJ cord-006870-f5w6fw6q 1321 13 center center NN cord-006870-f5w6fw6q 1321 14 , , , cord-006870-f5w6fw6q 1321 15 excluding exclude VBG cord-006870-f5w6fw6q 1321 16 those those DT cord-006870-f5w6fw6q 1321 17 transitioned transition VBN cord-006870-f5w6fw6q 1321 18 to to IN cord-006870-f5w6fw6q 1321 19 comfort comfort NN cord-006870-f5w6fw6q 1321 20 care care NN cord-006870-f5w6fw6q 1321 21 within within IN cord-006870-f5w6fw6q 1321 22 24 24 CD cord-006870-f5w6fw6q 1321 23 hours hour NNS cord-006870-f5w6fw6q 1321 24 . . . cord-006870-f5w6fw6q 1322 1 We -PRON- PRP cord-006870-f5w6fw6q 1322 2 abstracted abstract VBD cord-006870-f5w6fw6q 1322 3 demographic demographic JJ cord-006870-f5w6fw6q 1322 4 and and CC cord-006870-f5w6fw6q 1322 5 clinical clinical JJ cord-006870-f5w6fw6q 1322 6 variables variable NNS cord-006870-f5w6fw6q 1322 7 from from IN cord-006870-f5w6fw6q 1322 8 the the DT cord-006870-f5w6fw6q 1322 9 medical medical JJ cord-006870-f5w6fw6q 1322 10 record record NN cord-006870-f5w6fw6q 1322 11 . . . cord-006870-f5w6fw6q 1323 1 We -PRON- PRP cord-006870-f5w6fw6q 1323 2 calculated calculate VBD cord-006870-f5w6fw6q 1323 3 the the DT cord-006870-f5w6fw6q 1323 4 total total JJ cord-006870-f5w6fw6q 1323 5 duration duration NN cord-006870-f5w6fw6q 1323 6 each each DT cord-006870-f5w6fw6q 1323 7 patient patient NN cord-006870-f5w6fw6q 1323 8 received receive VBD cord-006870-f5w6fw6q 1323 9 continuous continuous JJ cord-006870-f5w6fw6q 1323 10 infusion infusion NN cord-006870-f5w6fw6q 1323 11 of of IN cord-006870-f5w6fw6q 1323 12 an an DT cord-006870-f5w6fw6q 1323 13 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1323 14 medication medication NN cord-006870-f5w6fw6q 1323 15 . . . cord-006870-f5w6fw6q 1324 1 We -PRON- PRP cord-006870-f5w6fw6q 1324 2 categorized categorize VBD cord-006870-f5w6fw6q 1324 3 Glasgow Glasgow NNP cord-006870-f5w6fw6q 1324 4 Coma Coma NNP cord-006870-f5w6fw6q 1324 5 Scale Scale NNP cord-006870-f5w6fw6q 1324 6 score score NN cord-006870-f5w6fw6q 1324 7 as as IN cord-006870-f5w6fw6q 1324 8 14 14 CD cord-006870-f5w6fw6q 1324 9 - - SYM cord-006870-f5w6fw6q 1324 10 15 15 CD cord-006870-f5w6fw6q 1324 11 ; ; : cord-006870-f5w6fw6q 1324 12 8 8 CD cord-006870-f5w6fw6q 1324 13 - - SYM cord-006870-f5w6fw6q 1324 14 13 13 CD cord-006870-f5w6fw6q 1324 15 ; ; : cord-006870-f5w6fw6q 1324 16 or or CC cord-006870-f5w6fw6q 1324 17 < < XX cord-006870-f5w6fw6q 1324 18 8 8 CD cord-006870-f5w6fw6q 1324 19 . . . cord-006870-f5w6fw6q 1325 1 Two two CD cord-006870-f5w6fw6q 1325 2 reviewers reviewer NNS cord-006870-f5w6fw6q 1325 3 independently independently RB cord-006870-f5w6fw6q 1325 4 classified classify VBD cord-006870-f5w6fw6q 1325 5 ICH ICH NNP cord-006870-f5w6fw6q 1325 6 location location NN cord-006870-f5w6fw6q 1325 7 and and CC cord-006870-f5w6fw6q 1325 8 etiology etiology NN cord-006870-f5w6fw6q 1325 9 . . . cord-006870-f5w6fw6q 1326 1 We -PRON- PRP cord-006870-f5w6fw6q 1326 2 determined determine VBD cord-006870-f5w6fw6q 1326 3 univariate univariate JJ cord-006870-f5w6fw6q 1326 4 associations association NNS cord-006870-f5w6fw6q 1326 5 of of IN cord-006870-f5w6fw6q 1326 6 clinical clinical JJ cord-006870-f5w6fw6q 1326 7 variables variable NNS cord-006870-f5w6fw6q 1326 8 to to IN cord-006870-f5w6fw6q 1326 9 anti anti JJ cord-006870-f5w6fw6q 1326 10 - - JJ cord-006870-f5w6fw6q 1326 11 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1326 12 infusion infusion NN cord-006870-f5w6fw6q 1326 13 and and CC cord-006870-f5w6fw6q 1326 14 performed perform VBN cord-006870-f5w6fw6q 1326 15 regression regression NN cord-006870-f5w6fw6q 1326 16 analysis analysis NN cord-006870-f5w6fw6q 1326 17 to to TO cord-006870-f5w6fw6q 1326 18 determine determine VB cord-006870-f5w6fw6q 1326 19 the the DT cord-006870-f5w6fw6q 1326 20 effect effect NN cord-006870-f5w6fw6q 1326 21 of of IN cord-006870-f5w6fw6q 1326 22 continuous continuous JJ cord-006870-f5w6fw6q 1326 23 infusion infusion NN cord-006870-f5w6fw6q 1326 24 on on IN cord-006870-f5w6fw6q 1326 25 ICU ICU NNP cord-006870-f5w6fw6q 1326 26 LOS LOS NNP cord-006870-f5w6fw6q 1326 27 . . . cord-006870-f5w6fw6q 1327 1 We -PRON- PRP cord-006870-f5w6fw6q 1327 2 identified identify VBD cord-006870-f5w6fw6q 1327 3 495 495 CD cord-006870-f5w6fw6q 1327 4 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1327 5 ICH ICH NNP cord-006870-f5w6fw6q 1327 6 patients patient NNS cord-006870-f5w6fw6q 1327 7 and and CC cord-006870-f5w6fw6q 1327 8 excluded exclude VBD cord-006870-f5w6fw6q 1327 9 50 50 CD cord-006870-f5w6fw6q 1327 10 for for IN cord-006870-f5w6fw6q 1327 11 early early JJ cord-006870-f5w6fw6q 1327 12 comfort comfort NN cord-006870-f5w6fw6q 1327 13 care care NN cord-006870-f5w6fw6q 1327 14 . . . cord-006870-f5w6fw6q 1328 1 In in IN cord-006870-f5w6fw6q 1328 2 the the DT cord-006870-f5w6fw6q 1328 3 remaining remain VBG cord-006870-f5w6fw6q 1328 4 445 445 CD cord-006870-f5w6fw6q 1328 5 , , , cord-006870-f5w6fw6q 1328 6 mean mean JJ cord-006870-f5w6fw6q 1328 7 age age NN cord-006870-f5w6fw6q 1328 8 was be VBD cord-006870-f5w6fw6q 1328 9 70 70 CD cord-006870-f5w6fw6q 1328 10 [ [ -LRB- cord-006870-f5w6fw6q 1328 11 69 69 CD cord-006870-f5w6fw6q 1328 12 - - SYM cord-006870-f5w6fw6q 1328 13 71 71 CD cord-006870-f5w6fw6q 1328 14 ] ] -RRB- cord-006870-f5w6fw6q 1328 15 years year NNS cord-006870-f5w6fw6q 1329 1 , , , cord-006870-f5w6fw6q 1329 2 45 45 CD cord-006870-f5w6fw6q 1329 3 % % NN cord-006870-f5w6fw6q 1329 4 were be VBD cord-006870-f5w6fw6q 1329 5 female female JJ cord-006870-f5w6fw6q 1329 6 , , , cord-006870-f5w6fw6q 1329 7 median median JJ cord-006870-f5w6fw6q 1329 8 ICH ICH NNP cord-006870-f5w6fw6q 1329 9 score score NN cord-006870-f5w6fw6q 1329 10 was be VBD cord-006870-f5w6fw6q 1329 11 1 1 CD cord-006870-f5w6fw6q 1329 12 [ [ -LRB- cord-006870-f5w6fw6q 1329 13 1 1 CD cord-006870-f5w6fw6q 1329 14 - - SYM cord-006870-f5w6fw6q 1329 15 2 2 CD cord-006870-f5w6fw6q 1329 16 ] ] -RRB- cord-006870-f5w6fw6q 1329 17 , , , cord-006870-f5w6fw6q 1329 18 and and CC cord-006870-f5w6fw6q 1329 19 44 44 CD cord-006870-f5w6fw6q 1329 20 % % NN cord-006870-f5w6fw6q 1329 21 had have VBD cord-006870-f5w6fw6q 1329 22 lobar lobar NN cord-006870-f5w6fw6q 1329 23 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 1329 24 . . . cord-006870-f5w6fw6q 1330 1 Continuous continuous JJ cord-006870-f5w6fw6q 1330 2 infusion infusion NN cord-006870-f5w6fw6q 1330 3 included include VBD cord-006870-f5w6fw6q 1330 4 nicardipine nicardipine RB cord-006870-f5w6fw6q 1330 5 , , , cord-006870-f5w6fw6q 1330 6 clevidipine clevidipine NN cord-006870-f5w6fw6q 1330 7 , , , cord-006870-f5w6fw6q 1330 8 labetalol labetalol NN cord-006870-f5w6fw6q 1330 9 and and CC cord-006870-f5w6fw6q 1330 10 diltiazem diltiazem NN cord-006870-f5w6fw6q 1330 11 . . . cord-006870-f5w6fw6q 1331 1 A a DT cord-006870-f5w6fw6q 1331 2 total total NN cord-006870-f5w6fw6q 1331 3 of of IN cord-006870-f5w6fw6q 1331 4 127 127 CD cord-006870-f5w6fw6q 1331 5 ( ( -LRB- cord-006870-f5w6fw6q 1331 6 28 28 CD cord-006870-f5w6fw6q 1331 7 % % NN cord-006870-f5w6fw6q 1331 8 ) ) -RRB- cord-006870-f5w6fw6q 1331 9 patients patient NNS cord-006870-f5w6fw6q 1331 10 received receive VBD cord-006870-f5w6fw6q 1331 11 anti anti JJ cord-006870-f5w6fw6q 1331 12 - - JJ cord-006870-f5w6fw6q 1331 13 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1331 14 infusions infusion NNS cord-006870-f5w6fw6q 1331 15 , , , cord-006870-f5w6fw6q 1331 16 mean mean VBP cord-006870-f5w6fw6q 1331 17 13 13 CD cord-006870-f5w6fw6q 1331 18 hours hour NNS cord-006870-f5w6fw6q 1331 19 . . . cord-006870-f5w6fw6q 1332 1 Mean mean JJ cord-006870-f5w6fw6q 1332 2 time time NN cord-006870-f5w6fw6q 1332 3 to to IN cord-006870-f5w6fw6q 1332 4 enteral enteral JJ cord-006870-f5w6fw6q 1332 5 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1332 6 administration administration NN cord-006870-f5w6fw6q 1332 7 medication medication NN cord-006870-f5w6fw6q 1332 8 was be VBD cord-006870-f5w6fw6q 1332 9 32.5 32.5 CD cord-006870-f5w6fw6q 1332 10 hours hour NNS cord-006870-f5w6fw6q 1332 11 , , , cord-006870-f5w6fw6q 1332 12 and and CC cord-006870-f5w6fw6q 1332 13 mean mean VB cord-006870-f5w6fw6q 1332 14 ICU ICU NNP cord-006870-f5w6fw6q 1332 15 length length NN cord-006870-f5w6fw6q 1332 16 of of IN cord-006870-f5w6fw6q 1332 17 stay stay NN cord-006870-f5w6fw6q 1332 18 was be VBD cord-006870-f5w6fw6q 1332 19 3.4 3.4 CD cord-006870-f5w6fw6q 1332 20 days day NNS cord-006870-f5w6fw6q 1332 21 [ [ -LRB- cord-006870-f5w6fw6q 1332 22 3.0 3.0 CD cord-006870-f5w6fw6q 1332 23 -3.8 -3.8 NNP cord-006870-f5w6fw6q 1332 24 ] ] -RRB- cord-006870-f5w6fw6q 1332 25 . . . cord-006870-f5w6fw6q 1333 1 Predictors predictor NNS cord-006870-f5w6fw6q 1333 2 of of IN cord-006870-f5w6fw6q 1333 3 longer long JJR cord-006870-f5w6fw6q 1333 4 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1333 5 infusion infusion NN cord-006870-f5w6fw6q 1333 6 duration duration NN cord-006870-f5w6fw6q 1333 7 were be VBD cord-006870-f5w6fw6q 1333 8 male male JJ cord-006870-f5w6fw6q 1333 9 gender gender NN cord-006870-f5w6fw6q 1333 10 ( ( -LRB- cord-006870-f5w6fw6q 1333 11 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 1333 12 ) ) -RRB- cord-006870-f5w6fw6q 1333 13 , , , cord-006870-f5w6fw6q 1333 14 non non JJ cord-006870-f5w6fw6q 1333 15 - - JJ cord-006870-f5w6fw6q 1333 16 lobar lobar JJ cord-006870-f5w6fw6q 1333 17 ICH ICH NNP cord-006870-f5w6fw6q 1333 18 ( ( -LRB- cord-006870-f5w6fw6q 1333 19 p=0.0002 p=0.0002 NNP cord-006870-f5w6fw6q 1333 20 ) ) -RRB- cord-006870-f5w6fw6q 1333 21 , , , cord-006870-f5w6fw6q 1333 22 non non JJ cord-006870-f5w6fw6q 1333 23 - - JJ cord-006870-f5w6fw6q 1333 24 caucasian caucasian JJ cord-006870-f5w6fw6q 1333 25 race race NN cord-006870-f5w6fw6q 1333 26 ( ( -LRB- cord-006870-f5w6fw6q 1333 27 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1333 28 ) ) -RRB- cord-006870-f5w6fw6q 1333 29 , , , cord-006870-f5w6fw6q 1333 30 younger young JJR cord-006870-f5w6fw6q 1333 31 age age NN cord-006870-f5w6fw6q 1333 32 ( ( -LRB- cord-006870-f5w6fw6q 1333 33 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 1333 34 ) ) -RRB- cord-006870-f5w6fw6q 1333 35 , , , cord-006870-f5w6fw6q 1333 36 higher high JJR cord-006870-f5w6fw6q 1333 37 initial initial JJ cord-006870-f5w6fw6q 1333 38 systolic systolic NN cord-006870-f5w6fw6q 1333 39 ( ( -LRB- cord-006870-f5w6fw6q 1333 40 p=0.03 p=0.03 NN cord-006870-f5w6fw6q 1333 41 ) ) -RRB- cord-006870-f5w6fw6q 1333 42 and and CC cord-006870-f5w6fw6q 1333 43 diastolic diastolic JJ cord-006870-f5w6fw6q 1333 44 BP BP NNP cord-006870-f5w6fw6q 1333 45 ( ( -LRB- cord-006870-f5w6fw6q 1333 46 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 1333 47 ) ) -RRB- cord-006870-f5w6fw6q 1333 48 , , , cord-006870-f5w6fw6q 1333 49 worse bad JJR cord-006870-f5w6fw6q 1333 50 GCS GCS NNP cord-006870-f5w6fw6q 1333 51 category category NN cord-006870-f5w6fw6q 1333 52 ( ( -LRB- cord-006870-f5w6fw6q 1333 53 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1333 54 ) ) -RRB- cord-006870-f5w6fw6q 1333 55 , , , cord-006870-f5w6fw6q 1333 56 and and CC cord-006870-f5w6fw6q 1333 57 longer long JJR cord-006870-f5w6fw6q 1333 58 time time NN cord-006870-f5w6fw6q 1333 59 to to IN cord-006870-f5w6fw6q 1333 60 first first JJ cord-006870-f5w6fw6q 1333 61 enteral enteral JJ cord-006870-f5w6fw6q 1333 62 medication medication NN cord-006870-f5w6fw6q 1333 63 ( ( -LRB- cord-006870-f5w6fw6q 1333 64 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 1333 65 ) ) -RRB- cord-006870-f5w6fw6q 1333 66 . . . cord-006870-f5w6fw6q 1334 1 Anti anti JJ cord-006870-f5w6fw6q 1334 2 - - JJ cord-006870-f5w6fw6q 1334 3 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1334 4 infusion infusion NN cord-006870-f5w6fw6q 1334 5 duration duration NN cord-006870-f5w6fw6q 1334 6 independently independently RB cord-006870-f5w6fw6q 1334 7 predicted predict VBD cord-006870-f5w6fw6q 1334 8 ICU ICU NNP cord-006870-f5w6fw6q 1334 9 LOS LOS NNP cord-006870-f5w6fw6q 1334 10 ( ( -LRB- cord-006870-f5w6fw6q 1334 11 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 1334 12 ) ) -RRB- cord-006870-f5w6fw6q 1334 13 after after IN cord-006870-f5w6fw6q 1334 14 adjusting adjust VBG cord-006870-f5w6fw6q 1334 15 for for IN cord-006870-f5w6fw6q 1334 16 age age NN cord-006870-f5w6fw6q 1334 17 , , , cord-006870-f5w6fw6q 1334 18 race race NN cord-006870-f5w6fw6q 1334 19 , , , cord-006870-f5w6fw6q 1334 20 GCS GCS NNP cord-006870-f5w6fw6q 1334 21 category category NN cord-006870-f5w6fw6q 1334 22 , , , cord-006870-f5w6fw6q 1334 23 time time NN cord-006870-f5w6fw6q 1334 24 to to IN cord-006870-f5w6fw6q 1334 25 enteral enteral NNP cord-006870-f5w6fw6q 1334 26 antihypertensives antihypertensives NNP cord-006870-f5w6fw6q 1334 27 , , , cord-006870-f5w6fw6q 1334 28 and and CC cord-006870-f5w6fw6q 1334 29 ICH ICH NNP cord-006870-f5w6fw6q 1334 30 score score VB cord-006870-f5w6fw6q 1334 31 . . . cord-006870-f5w6fw6q 1335 1 Worse bad JJR cord-006870-f5w6fw6q 1335 2 GCS GCS NNP cord-006870-f5w6fw6q 1335 3 category category NN cord-006870-f5w6fw6q 1335 4 , , , cord-006870-f5w6fw6q 1335 5 younger young JJR cord-006870-f5w6fw6q 1335 6 age age NN cord-006870-f5w6fw6q 1335 7 , , , cord-006870-f5w6fw6q 1335 8 non non JJ cord-006870-f5w6fw6q 1335 9 - - JJ cord-006870-f5w6fw6q 1335 10 lobar lobar JJ cord-006870-f5w6fw6q 1335 11 ICH ICH NNP cord-006870-f5w6fw6q 1335 12 location location NN cord-006870-f5w6fw6q 1335 13 , , , cord-006870-f5w6fw6q 1335 14 and and CC cord-006870-f5w6fw6q 1335 15 race race NN cord-006870-f5w6fw6q 1335 16 are be VBP cord-006870-f5w6fw6q 1335 17 significant significant JJ cord-006870-f5w6fw6q 1335 18 independent independent JJ cord-006870-f5w6fw6q 1335 19 predictors predictor NNS cord-006870-f5w6fw6q 1335 20 continuous continuous JJ cord-006870-f5w6fw6q 1335 21 IV iv CD cord-006870-f5w6fw6q 1335 22 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1335 23 infusion infusion NN cord-006870-f5w6fw6q 1335 24 duration duration NN cord-006870-f5w6fw6q 1335 25 , , , cord-006870-f5w6fw6q 1335 26 which which WDT cord-006870-f5w6fw6q 1335 27 is be VBZ cord-006870-f5w6fw6q 1335 28 significantly significantly RB cord-006870-f5w6fw6q 1335 29 associated associate VBN cord-006870-f5w6fw6q 1335 30 with with IN cord-006870-f5w6fw6q 1335 31 longer long JJR cord-006870-f5w6fw6q 1335 32 ICU ICU NNP cord-006870-f5w6fw6q 1335 33 stay stay NN cord-006870-f5w6fw6q 1335 34 . . . cord-006870-f5w6fw6q 1336 1 Patients patient NNS cord-006870-f5w6fw6q 1336 2 with with IN cord-006870-f5w6fw6q 1336 3 sICH sich NN cord-006870-f5w6fw6q 1336 4 have have VB cord-006870-f5w6fw6q 1336 5 a a DT cord-006870-f5w6fw6q 1336 6 high high JJ cord-006870-f5w6fw6q 1336 7 risk risk NN cord-006870-f5w6fw6q 1336 8 of of IN cord-006870-f5w6fw6q 1336 9 VTE VTE NNP cord-006870-f5w6fw6q 1336 10 . . . cord-006870-f5w6fw6q 1337 1 Pharmacological pharmacological JJ cord-006870-f5w6fw6q 1337 2 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 1337 3 such such JJ cord-006870-f5w6fw6q 1337 4 as as IN cord-006870-f5w6fw6q 1337 5 unfractionated unfractionated NNP cord-006870-f5w6fw6q 1337 6 heparin(UFH heparin(UFH NNP cord-006870-f5w6fw6q 1337 7 ) ) -RRB- cord-006870-f5w6fw6q 1337 8 has have VBZ cord-006870-f5w6fw6q 1337 9 been be VBN cord-006870-f5w6fw6q 1337 10 demonstrated demonstrate VBN cord-006870-f5w6fw6q 1337 11 to to TO cord-006870-f5w6fw6q 1337 12 reduce reduce VB cord-006870-f5w6fw6q 1337 13 VTE VTE NNP cord-006870-f5w6fw6q 1337 14 . . . cord-006870-f5w6fw6q 1338 1 However however RB cord-006870-f5w6fw6q 1338 2 , , , cord-006870-f5w6fw6q 1338 3 published publish VBN cord-006870-f5w6fw6q 1338 4 datasets dataset NNS cord-006870-f5w6fw6q 1338 5 exclude exclude VBP cord-006870-f5w6fw6q 1338 6 patients patient NNS cord-006870-f5w6fw6q 1338 7 with with IN cord-006870-f5w6fw6q 1338 8 recent recent JJ cord-006870-f5w6fw6q 1338 9 ICH ICH NNP cord-006870-f5w6fw6q 1338 10 out out IN cord-006870-f5w6fw6q 1338 11 of of IN cord-006870-f5w6fw6q 1338 12 concern concern NN cord-006870-f5w6fw6q 1338 13 for for IN cord-006870-f5w6fw6q 1338 14 hematoma hematoma NN cord-006870-f5w6fw6q 1338 15 enlargement enlargement NN cord-006870-f5w6fw6q 1338 16 . . . cord-006870-f5w6fw6q 1339 1 AHA/ AHA/ NNP cord-006870-f5w6fw6q 1340 1 ASA ASA NNP cord-006870-f5w6fw6q 1340 2 guidelines guideline NNS cord-006870-f5w6fw6q 1340 3 recommend recommend VBP cord-006870-f5w6fw6q 1340 4 UFH UFH NNP cord-006870-f5w6fw6q 1340 5 1 1 CD cord-006870-f5w6fw6q 1340 6 - - SYM cord-006870-f5w6fw6q 1340 7 4 4 CD cord-006870-f5w6fw6q 1340 8 days day NNS cord-006870-f5w6fw6q 1340 9 after after IN cord-006870-f5w6fw6q 1340 10 hematoma hematoma NN cord-006870-f5w6fw6q 1340 11 stabilization stabilization NN cord-006870-f5w6fw6q 1340 12 while while IN cord-006870-f5w6fw6q 1340 13 the the DT cord-006870-f5w6fw6q 1340 14 ESO ESO NNP cord-006870-f5w6fw6q 1340 15 has have VBZ cord-006870-f5w6fw6q 1340 16 no no DT cord-006870-f5w6fw6q 1340 17 recommendations recommendation NNS cord-006870-f5w6fw6q 1340 18 on on IN cord-006870-f5w6fw6q 1340 19 timing timing NN cord-006870-f5w6fw6q 1340 20 of of IN cord-006870-f5w6fw6q 1340 21 UFH UFH NNP cord-006870-f5w6fw6q 1340 22 . . . cord-006870-f5w6fw6q 1341 1 There there EX cord-006870-f5w6fw6q 1341 2 are be VBP cord-006870-f5w6fw6q 1341 3 few few JJ cord-006870-f5w6fw6q 1341 4 data datum NNS cord-006870-f5w6fw6q 1341 5 for for IN cord-006870-f5w6fw6q 1341 6 patients patient NNS cord-006870-f5w6fw6q 1341 7 who who WP cord-006870-f5w6fw6q 1341 8 received receive VBD cord-006870-f5w6fw6q 1341 9 UFH UFH NNP cord-006870-f5w6fw6q 1341 10 before before IN cord-006870-f5w6fw6q 1341 11 48 48 CD cord-006870-f5w6fw6q 1341 12 hours hour NNS cord-006870-f5w6fw6q 1341 13 . . . cord-006870-f5w6fw6q 1342 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1342 2 institutional institutional JJ cord-006870-f5w6fw6q 1342 3 practice practice NN cord-006870-f5w6fw6q 1342 4 is be VBZ cord-006870-f5w6fw6q 1342 5 to to TO cord-006870-f5w6fw6q 1342 6 begin begin VB cord-006870-f5w6fw6q 1342 7 UFH UFH NNP cord-006870-f5w6fw6q 1342 8 following follow VBG cord-006870-f5w6fw6q 1342 9 sICH sich NN cord-006870-f5w6fw6q 1342 10 after after IN cord-006870-f5w6fw6q 1342 11 24 24 CD cord-006870-f5w6fw6q 1342 12 hours hour NNS cord-006870-f5w6fw6q 1342 13 of of IN cord-006870-f5w6fw6q 1342 14 clinical clinical JJ cord-006870-f5w6fw6q 1342 15 and and CC cord-006870-f5w6fw6q 1342 16 radiographic radiographic JJ cord-006870-f5w6fw6q 1342 17 stability stability NN cord-006870-f5w6fw6q 1342 18 . . . cord-006870-f5w6fw6q 1343 1 We -PRON- PRP cord-006870-f5w6fw6q 1343 2 examine examine VBP cord-006870-f5w6fw6q 1343 3 the the DT cord-006870-f5w6fw6q 1343 4 impact impact NN cord-006870-f5w6fw6q 1343 5 of of IN cord-006870-f5w6fw6q 1343 6 this this DT cord-006870-f5w6fw6q 1343 7 practice practice NN cord-006870-f5w6fw6q 1343 8 on on IN cord-006870-f5w6fw6q 1343 9 risk risk NN cord-006870-f5w6fw6q 1343 10 of of IN cord-006870-f5w6fw6q 1343 11 hematoma hematoma NN cord-006870-f5w6fw6q 1343 12 expansion expansion NN cord-006870-f5w6fw6q 1343 13 . . . cord-006870-f5w6fw6q 1344 1 We -PRON- PRP cord-006870-f5w6fw6q 1344 2 performed perform VBD cord-006870-f5w6fw6q 1344 3 a a DT cord-006870-f5w6fw6q 1344 4 retrospective retrospective JJ cord-006870-f5w6fw6q 1344 5 cohort cohort NN cord-006870-f5w6fw6q 1344 6 analysis analysis NN cord-006870-f5w6fw6q 1344 7 of of IN cord-006870-f5w6fw6q 1344 8 87 87 CD cord-006870-f5w6fw6q 1344 9 sICH sich NN cord-006870-f5w6fw6q 1344 10 patients patient NNS cord-006870-f5w6fw6q 1344 11 admitted admit VBN cord-006870-f5w6fw6q 1344 12 in in IN cord-006870-f5w6fw6q 1344 13 2012 2012 CD cord-006870-f5w6fw6q 1344 14 - - SYM cord-006870-f5w6fw6q 1344 15 2013 2013 CD cord-006870-f5w6fw6q 1344 16 to to IN cord-006870-f5w6fw6q 1344 17 a a DT cord-006870-f5w6fw6q 1344 18 single single JJ cord-006870-f5w6fw6q 1344 19 US US NNP cord-006870-f5w6fw6q 1344 20 university university NN cord-006870-f5w6fw6q 1344 21 hospital hospital NN cord-006870-f5w6fw6q 1344 22 . . . cord-006870-f5w6fw6q 1345 1 Demographic demographic JJ cord-006870-f5w6fw6q 1345 2 and and CC cord-006870-f5w6fw6q 1345 3 clinical clinical JJ cord-006870-f5w6fw6q 1345 4 characteristics characteristic NNS cord-006870-f5w6fw6q 1345 5 were be VBD cord-006870-f5w6fw6q 1345 6 abstracted abstract VBN cord-006870-f5w6fw6q 1345 7 . . . cord-006870-f5w6fw6q 1346 1 ICH ICH NNP cord-006870-f5w6fw6q 1346 2 was be VBD cord-006870-f5w6fw6q 1346 3 measured measure VBN cord-006870-f5w6fw6q 1346 4 via via IN cord-006870-f5w6fw6q 1346 5 3D 3D NNP cord-006870-f5w6fw6q 1346 6 volumetrics volumetrics NNP cord-006870-f5w6fw6q 1346 7 for for IN cord-006870-f5w6fw6q 1346 8 an an DT cord-006870-f5w6fw6q 1346 9 admission admission NN cord-006870-f5w6fw6q 1346 10 CT CT NNP cord-006870-f5w6fw6q 1346 11 , , , cord-006870-f5w6fw6q 1346 12 a a DT cord-006870-f5w6fw6q 1346 13 24 24 CD cord-006870-f5w6fw6q 1346 14 hour hour NN cord-006870-f5w6fw6q 1346 15 follow follow NN cord-006870-f5w6fw6q 1346 16 - - HYPH cord-006870-f5w6fw6q 1346 17 up up NN cord-006870-f5w6fw6q 1346 18 , , , cord-006870-f5w6fw6q 1346 19 and and CC cord-006870-f5w6fw6q 1346 20 a a DT cord-006870-f5w6fw6q 1346 21 follow follow NN cord-006870-f5w6fw6q 1346 22 - - HYPH cord-006870-f5w6fw6q 1346 23 up up NN cord-006870-f5w6fw6q 1346 24 prior prior RB cord-006870-f5w6fw6q 1346 25 to to IN cord-006870-f5w6fw6q 1346 26 discharge discharge NN cord-006870-f5w6fw6q 1346 27 . . . cord-006870-f5w6fw6q 1347 1 Percent percent NN cord-006870-f5w6fw6q 1347 2 hematoma hematoma NN cord-006870-f5w6fw6q 1347 3 growth growth NN cord-006870-f5w6fw6q 1347 4 between between IN cord-006870-f5w6fw6q 1347 5 24-hour 24-hour JJ cord-006870-f5w6fw6q 1347 6 CT CT NNP cord-006870-f5w6fw6q 1347 7 and and CC cord-006870-f5w6fw6q 1347 8 discharge discharge NN cord-006870-f5w6fw6q 1347 9 CT CT NNP cord-006870-f5w6fw6q 1347 10 was be VBD cord-006870-f5w6fw6q 1347 11 calculated calculate VBN cord-006870-f5w6fw6q 1347 12 . . . cord-006870-f5w6fw6q 1348 1 Risk risk NN cord-006870-f5w6fw6q 1348 2 factors factor NNS cord-006870-f5w6fw6q 1348 3 for for IN cord-006870-f5w6fw6q 1348 4 expansion expansion NN cord-006870-f5w6fw6q 1348 5 > > SYM cord-006870-f5w6fw6q 1348 6 5 5 CD cord-006870-f5w6fw6q 1348 7 % % NN cord-006870-f5w6fw6q 1348 8 , , , cord-006870-f5w6fw6q 1348 9 including include VBG cord-006870-f5w6fw6q 1348 10 early early JJ cord-006870-f5w6fw6q 1348 11 heparin heparin NN cord-006870-f5w6fw6q 1348 12 use use NN cord-006870-f5w6fw6q 1348 13 , , , cord-006870-f5w6fw6q 1348 14 were be VBD cord-006870-f5w6fw6q 1348 15 analyzed analyze VBN cord-006870-f5w6fw6q 1348 16 via via IN cord-006870-f5w6fw6q 1348 17 oneway oneway NNP cord-006870-f5w6fw6q 1348 18 T t NN cord-006870-f5w6fw6q 1348 19 - - HYPH cord-006870-f5w6fw6q 1348 20 test test NN cord-006870-f5w6fw6q 1348 21 and and CC cord-006870-f5w6fw6q 1348 22 Chi Chi NNP cord-006870-f5w6fw6q 1348 23 - - HYPH cord-006870-f5w6fw6q 1348 24 squared square VBN cord-006870-f5w6fw6q 1348 25 tests test NNS cord-006870-f5w6fw6q 1348 26 . . . cord-006870-f5w6fw6q 1349 1 Results result NNS cord-006870-f5w6fw6q 1349 2 87 87 CD cord-006870-f5w6fw6q 1349 3 sICH sich NN cord-006870-f5w6fw6q 1349 4 patients patient NNS cord-006870-f5w6fw6q 1349 5 analyzed analyze VBN cord-006870-f5w6fw6q 1349 6 had have VBD cord-006870-f5w6fw6q 1349 7 a a DT cord-006870-f5w6fw6q 1349 8 median median NN cord-006870-f5w6fw6q 1349 9 ICH ICH NNP cord-006870-f5w6fw6q 1349 10 score score NN cord-006870-f5w6fw6q 1349 11 of of IN cord-006870-f5w6fw6q 1349 12 2(IQR1 2(iqr1 CD cord-006870-f5w6fw6q 1349 13 - - SYM cord-006870-f5w6fw6q 1349 14 3 3 CD cord-006870-f5w6fw6q 1349 15 ) ) -RRB- cord-006870-f5w6fw6q 1349 16 and and CC cord-006870-f5w6fw6q 1350 1 median median JJ cord-006870-f5w6fw6q 1350 2 admission admission NN cord-006870-f5w6fw6q 1350 3 GCS GCS NNP cord-006870-f5w6fw6q 1350 4 of of IN cord-006870-f5w6fw6q 1350 5 10(IQR6 10(iqr6 CD cord-006870-f5w6fw6q 1350 6 - - SYM cord-006870-f5w6fw6q 1350 7 13 13 CD cord-006870-f5w6fw6q 1350 8 ) ) -RRB- cord-006870-f5w6fw6q 1350 9 . . . cord-006870-f5w6fw6q 1351 1 39%(34/87 39%(34/87 LS cord-006870-f5w6fw6q 1351 2 ) ) -RRB- cord-006870-f5w6fw6q 1352 1 patients patient NNS cord-006870-f5w6fw6q 1352 2 received receive VBD cord-006870-f5w6fw6q 1352 3 early early JJ cord-006870-f5w6fw6q 1352 4 UFH UFH NNP cord-006870-f5w6fw6q 1352 5 . . . cord-006870-f5w6fw6q 1353 1 18%(16/87 18%(16/87 LS cord-006870-f5w6fw6q 1353 2 ) ) -RRB- cord-006870-f5w6fw6q 1353 3 suffered suffer VBN cord-006870-f5w6fw6q 1353 4 hematoma hematoma NN cord-006870-f5w6fw6q 1353 5 expansion expansion NN cord-006870-f5w6fw6q 1353 6 > > XX cord-006870-f5w6fw6q 1353 7 5 5 CD cord-006870-f5w6fw6q 1353 8 % % NN cord-006870-f5w6fw6q 1353 9 . . . cord-006870-f5w6fw6q 1354 1 Overall overall JJ cord-006870-f5w6fw6q 1354 2 mean mean JJ cord-006870-f5w6fw6q 1354 3 hematoma hematoma NN cord-006870-f5w6fw6q 1354 4 growth growth NN cord-006870-f5w6fw6q 1354 5 was be VBD cord-006870-f5w6fw6q 1354 6 higher high JJR cord-006870-f5w6fw6q 1354 7 with with IN cord-006870-f5w6fw6q 1354 8 early early JJ cord-006870-f5w6fw6q 1354 9 UFH UFH NNP cord-006870-f5w6fw6q 1354 10 ( ( -LRB- cord-006870-f5w6fw6q 1354 11 UFH24hr UFH24hr NNP cord-006870-f5w6fw6q 1354 12 -15%,p=0.0007 -15%,p=0.0007 NN cord-006870-f5w6fw6q 1354 13 ) ) -RRB- cord-006870-f5w6fw6q 1354 14 . . . cord-006870-f5w6fw6q 1355 1 In in IN cord-006870-f5w6fw6q 1355 2 multivariate multivariate JJ cord-006870-f5w6fw6q 1355 3 analysis analysis NN cord-006870-f5w6fw6q 1355 4 , , , cord-006870-f5w6fw6q 1355 5 ICH ICH NNP cord-006870-f5w6fw6q 1355 6 score score VBP cord-006870-f5w6fw6q 1355 7 , , , cord-006870-f5w6fw6q 1355 8 GCS GCS NNP cord-006870-f5w6fw6q 1355 9 and and CC cord-006870-f5w6fw6q 1355 10 initial initial JJ cord-006870-f5w6fw6q 1355 11 hematoma hematoma NN cord-006870-f5w6fw6q 1355 12 size size NN cord-006870-f5w6fw6q 1355 13 did do VBD cord-006870-f5w6fw6q 1355 14 not not RB cord-006870-f5w6fw6q 1355 15 predict predict VB cord-006870-f5w6fw6q 1355 16 > > SYM cord-006870-f5w6fw6q 1355 17 5 5 CD cord-006870-f5w6fw6q 1355 18 % % NN cord-006870-f5w6fw6q 1355 19 hematoma hematoma NN cord-006870-f5w6fw6q 1355 20 expansion expansion NN cord-006870-f5w6fw6q 1355 21 . . . cord-006870-f5w6fw6q 1356 1 Early early JJ cord-006870-f5w6fw6q 1356 2 VTE VTE NNP cord-006870-f5w6fw6q 1356 3 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 1356 4 at at IN cord-006870-f5w6fw6q 1356 5 24 24 CD cord-006870-f5w6fw6q 1356 6 hours hour NNS cord-006870-f5w6fw6q 1356 7 from from IN cord-006870-f5w6fw6q 1356 8 sICH sich NN cord-006870-f5w6fw6q 1356 9 had have VBD cord-006870-f5w6fw6q 1356 10 a a DT cord-006870-f5w6fw6q 1356 11 statistically statistically RB cord-006870-f5w6fw6q 1356 12 significant significant JJ cord-006870-f5w6fw6q 1356 13 increase increase NN cord-006870-f5w6fw6q 1356 14 in in IN cord-006870-f5w6fw6q 1356 15 hematoma hematoma NN cord-006870-f5w6fw6q 1356 16 size size NN cord-006870-f5w6fw6q 1356 17 , , , cord-006870-f5w6fw6q 1356 18 but but CC cord-006870-f5w6fw6q 1356 19 this this DT cord-006870-f5w6fw6q 1356 20 increase increase NN cord-006870-f5w6fw6q 1356 21 is be VBZ cord-006870-f5w6fw6q 1356 22 clinically clinically RB cord-006870-f5w6fw6q 1356 23 insignificant insignificant JJ cord-006870-f5w6fw6q 1356 24 . . . cord-006870-f5w6fw6q 1357 1 In in IN cord-006870-f5w6fw6q 1357 2 this this DT cord-006870-f5w6fw6q 1357 3 cohort cohort NN cord-006870-f5w6fw6q 1357 4 , , , cord-006870-f5w6fw6q 1357 5 early early RB cord-006870-f5w6fw6q 1357 6 UFH UFH NNP cord-006870-f5w6fw6q 1357 7 did do VBD cord-006870-f5w6fw6q 1357 8 not not RB cord-006870-f5w6fw6q 1357 9 increase increase VB cord-006870-f5w6fw6q 1357 10 risk risk NN cord-006870-f5w6fw6q 1357 11 of of IN cord-006870-f5w6fw6q 1357 12 significant significant JJ cord-006870-f5w6fw6q 1357 13 hematoma hematoma NN cord-006870-f5w6fw6q 1357 14 expansion expansion NN cord-006870-f5w6fw6q 1357 15 . . . cord-006870-f5w6fw6q 1358 1 Further further JJ cord-006870-f5w6fw6q 1358 2 prospective prospective JJ cord-006870-f5w6fw6q 1358 3 trials trial NNS cord-006870-f5w6fw6q 1358 4 are be VBP cord-006870-f5w6fw6q 1358 5 warranted warrant VBN cord-006870-f5w6fw6q 1358 6 , , , cord-006870-f5w6fw6q 1358 7 given give VBN cord-006870-f5w6fw6q 1358 8 the the DT cord-006870-f5w6fw6q 1358 9 high high JJ cord-006870-f5w6fw6q 1358 10 risk risk NN cord-006870-f5w6fw6q 1358 11 of of IN cord-006870-f5w6fw6q 1358 12 VTE VTE NNP cord-006870-f5w6fw6q 1358 13 in in IN cord-006870-f5w6fw6q 1358 14 this this DT cord-006870-f5w6fw6q 1358 15 population population NN cord-006870-f5w6fw6q 1358 16 . . . cord-006870-f5w6fw6q 1359 1 Antiplatelet Antiplatelet NNP cord-006870-f5w6fw6q 1359 2 therapy therapy NN cord-006870-f5w6fw6q 1359 3 at at IN cord-006870-f5w6fw6q 1359 4 the the DT cord-006870-f5w6fw6q 1359 5 time time NN cord-006870-f5w6fw6q 1359 6 of of IN cord-006870-f5w6fw6q 1359 7 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1359 8 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1359 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1359 10 ( ( -LRB- cord-006870-f5w6fw6q 1359 11 sICH sich NN cord-006870-f5w6fw6q 1359 12 ) ) -RRB- cord-006870-f5w6fw6q 1359 13 may may MD cord-006870-f5w6fw6q 1359 14 increase increase VB cord-006870-f5w6fw6q 1359 15 the the DT cord-006870-f5w6fw6q 1359 16 risk risk NN cord-006870-f5w6fw6q 1359 17 of of IN cord-006870-f5w6fw6q 1359 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1359 19 expansion expansion NN cord-006870-f5w6fw6q 1359 20 and and CC cord-006870-f5w6fw6q 1359 21 mortality mortality NN cord-006870-f5w6fw6q 1359 22 . . . cord-006870-f5w6fw6q 1360 1 Current current JJ cord-006870-f5w6fw6q 1360 2 guidelines guideline NNS cord-006870-f5w6fw6q 1360 3 recommend recommend VBP cord-006870-f5w6fw6q 1360 4 consideration consideration NN cord-006870-f5w6fw6q 1360 5 of of IN cord-006870-f5w6fw6q 1360 6 a a DT cord-006870-f5w6fw6q 1360 7 single single JJ cord-006870-f5w6fw6q 1360 8 dose dose NN cord-006870-f5w6fw6q 1360 9 of of IN cord-006870-f5w6fw6q 1360 10 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1360 11 in in IN cord-006870-f5w6fw6q 1360 12 sICH sich NN cord-006870-f5w6fw6q 1360 13 associated associate VBN cord-006870-f5w6fw6q 1360 14 with with IN cord-006870-f5w6fw6q 1360 15 cyclooxygenase-1 cyclooxygenase-1 NNP cord-006870-f5w6fw6q 1360 16 inhibitors inhibitor NNS cord-006870-f5w6fw6q 1360 17 or or CC cord-006870-f5w6fw6q 1360 18 adenosine adenosine NN cord-006870-f5w6fw6q 1360 19 diphosphate diphosphate NN cord-006870-f5w6fw6q 1360 20 receptor receptor NN cord-006870-f5w6fw6q 1360 21 inhibitors inhibitor NNS cord-006870-f5w6fw6q 1360 22 . . . cord-006870-f5w6fw6q 1361 1 This this DT cord-006870-f5w6fw6q 1361 2 study study NN cord-006870-f5w6fw6q 1361 3 sought seek VBD cord-006870-f5w6fw6q 1361 4 to to TO cord-006870-f5w6fw6q 1361 5 compare compare VB cord-006870-f5w6fw6q 1361 6 outcomes outcome NNS cord-006870-f5w6fw6q 1361 7 in in IN cord-006870-f5w6fw6q 1361 8 patients patient NNS cord-006870-f5w6fw6q 1361 9 that that WDT cord-006870-f5w6fw6q 1361 10 received receive VBD cord-006870-f5w6fw6q 1361 11 desmopressin desmopressin NN cord-006870-f5w6fw6q 1361 12 for for IN cord-006870-f5w6fw6q 1361 13 antiplatelet antiplatelet JJ cord-006870-f5w6fw6q 1361 14 reversal reversal NN cord-006870-f5w6fw6q 1361 15 in in IN cord-006870-f5w6fw6q 1361 16 the the DT cord-006870-f5w6fw6q 1361 17 setting setting NN cord-006870-f5w6fw6q 1361 18 of of IN cord-006870-f5w6fw6q 1361 19 sICH sich NN cord-006870-f5w6fw6q 1361 20 to to IN cord-006870-f5w6fw6q 1361 21 similar similar JJ cord-006870-f5w6fw6q 1361 22 patients patient NNS cord-006870-f5w6fw6q 1361 23 that that WDT cord-006870-f5w6fw6q 1361 24 did do VBD cord-006870-f5w6fw6q 1361 25 not not RB cord-006870-f5w6fw6q 1361 26 receive receive VB cord-006870-f5w6fw6q 1361 27 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1361 28 . . . cord-006870-f5w6fw6q 1362 1 This this DT cord-006870-f5w6fw6q 1362 2 retrospective retrospective JJ cord-006870-f5w6fw6q 1362 3 chart chart NN cord-006870-f5w6fw6q 1362 4 review review NN cord-006870-f5w6fw6q 1362 5 of of IN cord-006870-f5w6fw6q 1362 6 the the DT cord-006870-f5w6fw6q 1362 7 electronic electronic JJ cord-006870-f5w6fw6q 1362 8 medical medical JJ cord-006870-f5w6fw6q 1362 9 record record NN cord-006870-f5w6fw6q 1362 10 included include VBD cord-006870-f5w6fw6q 1362 11 adult adult NN cord-006870-f5w6fw6q 1362 12 patients patient NNS cord-006870-f5w6fw6q 1362 13 admitted admit VBN cord-006870-f5w6fw6q 1362 14 for for IN cord-006870-f5w6fw6q 1362 15 sICH sich NN cord-006870-f5w6fw6q 1362 16 that that WDT cord-006870-f5w6fw6q 1362 17 were be VBD cord-006870-f5w6fw6q 1362 18 on on IN cord-006870-f5w6fw6q 1362 19 antiplatelet antiplatelet JJ cord-006870-f5w6fw6q 1362 20 agents agent NNS cord-006870-f5w6fw6q 1362 21 at at IN cord-006870-f5w6fw6q 1362 22 the the DT cord-006870-f5w6fw6q 1362 23 time time NN cord-006870-f5w6fw6q 1362 24 of of IN cord-006870-f5w6fw6q 1362 25 diagnosis diagnosis NN cord-006870-f5w6fw6q 1362 26 . . . cord-006870-f5w6fw6q 1363 1 Patients patient NNS cord-006870-f5w6fw6q 1363 2 that that WDT cord-006870-f5w6fw6q 1363 3 received receive VBD cord-006870-f5w6fw6q 1363 4 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1363 5 were be VBD cord-006870-f5w6fw6q 1363 6 compared compare VBN cord-006870-f5w6fw6q 1363 7 to to IN cord-006870-f5w6fw6q 1363 8 similar similar JJ cord-006870-f5w6fw6q 1363 9 patients patient NNS cord-006870-f5w6fw6q 1363 10 that that WDT cord-006870-f5w6fw6q 1363 11 did do VBD cord-006870-f5w6fw6q 1363 12 not not RB cord-006870-f5w6fw6q 1363 13 receive receive VB cord-006870-f5w6fw6q 1363 14 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1363 15 . . . cord-006870-f5w6fw6q 1364 1 Exclusion exclusion NN cord-006870-f5w6fw6q 1364 2 criteria criterion NNS cord-006870-f5w6fw6q 1364 3 included include VBD cord-006870-f5w6fw6q 1364 4 traumatic traumatic JJ cord-006870-f5w6fw6q 1364 5 brain brain NN cord-006870-f5w6fw6q 1364 6 injury injury NN cord-006870-f5w6fw6q 1364 7 , , , cord-006870-f5w6fw6q 1364 8 active active JJ cord-006870-f5w6fw6q 1364 9 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 1364 10 and and CC cord-006870-f5w6fw6q 1364 11 thrombocytopenia thrombocytopenia NN cord-006870-f5w6fw6q 1364 12 . . . cord-006870-f5w6fw6q 1365 1 The the DT cord-006870-f5w6fw6q 1365 2 primary primary JJ cord-006870-f5w6fw6q 1365 3 outcome outcome NN cord-006870-f5w6fw6q 1365 4 was be VBD cord-006870-f5w6fw6q 1365 5 the the DT cord-006870-f5w6fw6q 1365 6 incidence incidence NN cord-006870-f5w6fw6q 1365 7 of of IN cord-006870-f5w6fw6q 1365 8 hematoma hematoma NN cord-006870-f5w6fw6q 1365 9 expansion expansion NN cord-006870-f5w6fw6q 1365 10 . . . cord-006870-f5w6fw6q 1366 1 Additional additional JJ cord-006870-f5w6fw6q 1366 2 outcomes outcome NNS cord-006870-f5w6fw6q 1366 3 included include VBD cord-006870-f5w6fw6q 1366 4 average average JJ cord-006870-f5w6fw6q 1366 5 increase increase NN cord-006870-f5w6fw6q 1366 6 in in IN cord-006870-f5w6fw6q 1366 7 hematoma hematoma NN cord-006870-f5w6fw6q 1366 8 volume volume NN cord-006870-f5w6fw6q 1366 9 , , , cord-006870-f5w6fw6q 1366 10 in in IN cord-006870-f5w6fw6q 1366 11 - - HYPH cord-006870-f5w6fw6q 1366 12 hospital hospital NN cord-006870-f5w6fw6q 1366 13 mortality mortality NN cord-006870-f5w6fw6q 1366 14 and and CC cord-006870-f5w6fw6q 1366 15 functional functional JJ cord-006870-f5w6fw6q 1366 16 outcome outcome NN cord-006870-f5w6fw6q 1366 17 at at IN cord-006870-f5w6fw6q 1366 18 hospital hospital NN cord-006870-f5w6fw6q 1366 19 discharge discharge NN cord-006870-f5w6fw6q 1366 20 . . . cord-006870-f5w6fw6q 1367 1 Overall overall RB cord-006870-f5w6fw6q 1367 2 , , , cord-006870-f5w6fw6q 1367 3 73 73 CD cord-006870-f5w6fw6q 1367 4 patients patient NNS cord-006870-f5w6fw6q 1367 5 ( ( -LRB- cord-006870-f5w6fw6q 1367 6 36 36 CD cord-006870-f5w6fw6q 1367 7 received receive VBN cord-006870-f5w6fw6q 1367 8 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1367 9 , , , cord-006870-f5w6fw6q 1367 10 37 37 CD cord-006870-f5w6fw6q 1367 11 did do VBD cord-006870-f5w6fw6q 1367 12 not not RB cord-006870-f5w6fw6q 1367 13 receive receive VB cord-006870-f5w6fw6q 1367 14 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1367 15 ) ) -RRB- cord-006870-f5w6fw6q 1367 16 were be VBD cord-006870-f5w6fw6q 1367 17 included include VBN cord-006870-f5w6fw6q 1367 18 for for IN cord-006870-f5w6fw6q 1367 19 analysis analysis NN cord-006870-f5w6fw6q 1367 20 . . . cord-006870-f5w6fw6q 1368 1 Incidence incidence NN cord-006870-f5w6fw6q 1368 2 of of IN cord-006870-f5w6fw6q 1368 3 hematoma hematoma NN cord-006870-f5w6fw6q 1368 4 expansion expansion NN cord-006870-f5w6fw6q 1368 5 was be VBD cord-006870-f5w6fw6q 1368 6 not not RB cord-006870-f5w6fw6q 1368 7 different different JJ cord-006870-f5w6fw6q 1368 8 between between IN cord-006870-f5w6fw6q 1368 9 groups group NNS cord-006870-f5w6fw6q 1368 10 ( ( -LRB- cord-006870-f5w6fw6q 1368 11 36 36 CD cord-006870-f5w6fw6q 1368 12 % % NN cord-006870-f5w6fw6q 1368 13 with with IN cord-006870-f5w6fw6q 1368 14 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1368 15 vs vs IN cord-006870-f5w6fw6q 1368 16 22 22 CD cord-006870-f5w6fw6q 1368 17 % % NN cord-006870-f5w6fw6q 1368 18 without without IN cord-006870-f5w6fw6q 1368 19 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1368 20 , , , cord-006870-f5w6fw6q 1368 21 p=0.17 p=0.17 NNP cord-006870-f5w6fw6q 1368 22 ) ) -RRB- cord-006870-f5w6fw6q 1368 23 . . . cord-006870-f5w6fw6q 1369 1 Average average JJ cord-006870-f5w6fw6q 1369 2 largest large JJS cord-006870-f5w6fw6q 1369 3 increase increase NN cord-006870-f5w6fw6q 1369 4 in in IN cord-006870-f5w6fw6q 1369 5 hematoma hematoma NN cord-006870-f5w6fw6q 1369 6 volume volume NN cord-006870-f5w6fw6q 1369 7 on on IN cord-006870-f5w6fw6q 1369 8 follow follow NN cord-006870-f5w6fw6q 1369 9 - - HYPH cord-006870-f5w6fw6q 1369 10 up up NN cord-006870-f5w6fw6q 1369 11 imaging imaging NN cord-006870-f5w6fw6q 1369 12 from from IN cord-006870-f5w6fw6q 1369 13 baseline baseline NN cord-006870-f5w6fw6q 1369 14 was be VBD cord-006870-f5w6fw6q 1369 15 not not RB cord-006870-f5w6fw6q 1369 16 different different JJ cord-006870-f5w6fw6q 1370 1 ( ( -LRB- cord-006870-f5w6fw6q 1370 2 10.5±16.7 10.5±16.7 CD cord-006870-f5w6fw6q 1370 3 mL ml NN cord-006870-f5w6fw6q 1370 4 with with IN cord-006870-f5w6fw6q 1370 5 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1370 6 vs vs IN cord-006870-f5w6fw6q 1370 7 10.2±26.7 10.2±26.7 CD cord-006870-f5w6fw6q 1370 8 mL ml NN cord-006870-f5w6fw6q 1370 9 without without IN cord-006870-f5w6fw6q 1370 10 desmopressin desmopressin NN cord-006870-f5w6fw6q 1370 11 , , , cord-006870-f5w6fw6q 1370 12 p=0.96 p=0.96 NNP cord-006870-f5w6fw6q 1370 13 . . . cord-006870-f5w6fw6q 1371 1 In in IN cord-006870-f5w6fw6q 1371 2 - - HYPH cord-006870-f5w6fw6q 1371 3 hospital hospital NN cord-006870-f5w6fw6q 1371 4 mortality mortality NN cord-006870-f5w6fw6q 1371 5 was be VBD cord-006870-f5w6fw6q 1371 6 significantly significantly RB cord-006870-f5w6fw6q 1371 7 higher high JJR cord-006870-f5w6fw6q 1371 8 in in IN cord-006870-f5w6fw6q 1371 9 the the DT cord-006870-f5w6fw6q 1371 10 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1371 11 group group NN cord-006870-f5w6fw6q 1371 12 ( ( -LRB- cord-006870-f5w6fw6q 1371 13 20 20 CD cord-006870-f5w6fw6q 1371 14 % % NN cord-006870-f5w6fw6q 1371 15 vs vs IN cord-006870-f5w6fw6q 1371 16 8 8 CD cord-006870-f5w6fw6q 1371 17 % % NN cord-006870-f5w6fw6q 1371 18 without without IN cord-006870-f5w6fw6q 1371 19 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1371 20 , , , cord-006870-f5w6fw6q 1371 21 p=0.016 p=0.016 JJS cord-006870-f5w6fw6q 1371 22 ) ) -RRB- cord-006870-f5w6fw6q 1371 23 as as RB cord-006870-f5w6fw6q 1371 24 well well RB cord-006870-f5w6fw6q 1371 25 as as IN cord-006870-f5w6fw6q 1371 26 the the DT cord-006870-f5w6fw6q 1371 27 incidence incidence NN cord-006870-f5w6fw6q 1371 28 of of IN cord-006870-f5w6fw6q 1371 29 a a DT cord-006870-f5w6fw6q 1371 30 Modified Modified NNP cord-006870-f5w6fw6q 1371 31 Rankin Rankin NNP cord-006870-f5w6fw6q 1371 32 Score Score NNP cord-006870-f5w6fw6q 1371 33 of of IN cord-006870-f5w6fw6q 1371 34 4 4 CD cord-006870-f5w6fw6q 1371 35 - - SYM cord-006870-f5w6fw6q 1371 36 6 6 CD cord-006870-f5w6fw6q 1371 37 at at IN cord-006870-f5w6fw6q 1371 38 discharge discharge NN cord-006870-f5w6fw6q 1371 39 ( ( -LRB- cord-006870-f5w6fw6q 1371 40 39 39 CD cord-006870-f5w6fw6q 1371 41 % % NN cord-006870-f5w6fw6q 1371 42 vs vs IN cord-006870-f5w6fw6q 1371 43 28 28 CD cord-006870-f5w6fw6q 1371 44 % % NN cord-006870-f5w6fw6q 1371 45 without without IN cord-006870-f5w6fw6q 1371 46 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1371 47 , , , cord-006870-f5w6fw6q 1371 48 p=0.029 p=0.029 NNP cord-006870-f5w6fw6q 1371 49 ) ) -RRB- cord-006870-f5w6fw6q 1371 50 . . . cord-006870-f5w6fw6q 1372 1 Administration Administration NNP cord-006870-f5w6fw6q 1372 2 of of IN cord-006870-f5w6fw6q 1372 3 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1372 4 for for IN cord-006870-f5w6fw6q 1372 5 antiplatelet antiplatelet JJ cord-006870-f5w6fw6q 1372 6 reversal reversal NN cord-006870-f5w6fw6q 1372 7 in in IN cord-006870-f5w6fw6q 1372 8 sICH sich NN cord-006870-f5w6fw6q 1372 9 does do VBZ cord-006870-f5w6fw6q 1372 10 not not RB cord-006870-f5w6fw6q 1372 11 appear appear VB cord-006870-f5w6fw6q 1372 12 to to TO cord-006870-f5w6fw6q 1372 13 reduce reduce VB cord-006870-f5w6fw6q 1372 14 the the DT cord-006870-f5w6fw6q 1372 15 incidence incidence NN cord-006870-f5w6fw6q 1372 16 of of IN cord-006870-f5w6fw6q 1372 17 hematoma hematoma NN cord-006870-f5w6fw6q 1372 18 expansion expansion NN cord-006870-f5w6fw6q 1372 19 . . . cord-006870-f5w6fw6q 1373 1 Further further JJ cord-006870-f5w6fw6q 1373 2 studies study NNS cord-006870-f5w6fw6q 1373 3 assessing assess VBG cord-006870-f5w6fw6q 1373 4 temporal temporal JJ cord-006870-f5w6fw6q 1373 5 relation relation NN cord-006870-f5w6fw6q 1373 6 of of IN cord-006870-f5w6fw6q 1373 7 desmopressin desmopressin NNP cord-006870-f5w6fw6q 1373 8 administration administration NNP cord-006870-f5w6fw6q 1373 9 and and CC cord-006870-f5w6fw6q 1373 10 hematoma hematoma NN cord-006870-f5w6fw6q 1373 11 expansion expansion NN cord-006870-f5w6fw6q 1373 12 are be VBP cord-006870-f5w6fw6q 1373 13 needed need VBN cord-006870-f5w6fw6q 1373 14 to to TO cord-006870-f5w6fw6q 1373 15 confirm confirm VB cord-006870-f5w6fw6q 1373 16 the the DT cord-006870-f5w6fw6q 1373 17 results result NNS cord-006870-f5w6fw6q 1373 18 of of IN cord-006870-f5w6fw6q 1373 19 this this DT cord-006870-f5w6fw6q 1373 20 single single JJ cord-006870-f5w6fw6q 1373 21 - - HYPH cord-006870-f5w6fw6q 1373 22 center center NN cord-006870-f5w6fw6q 1373 23 retrospective retrospective JJ cord-006870-f5w6fw6q 1373 24 study study NN cord-006870-f5w6fw6q 1373 25 . . . cord-006870-f5w6fw6q 1374 1 Clinical clinical JJ cord-006870-f5w6fw6q 1374 2 outcome outcome NN cord-006870-f5w6fw6q 1374 3 after after IN cord-006870-f5w6fw6q 1374 4 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1374 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1374 6 ( ( -LRB- cord-006870-f5w6fw6q 1374 7 ICH ICH NNP cord-006870-f5w6fw6q 1374 8 ) ) -RRB- cord-006870-f5w6fw6q 1374 9 remains remain VBZ cord-006870-f5w6fw6q 1374 10 poor poor JJ cord-006870-f5w6fw6q 1374 11 . . . cord-006870-f5w6fw6q 1375 1 Definitive definitive JJ cord-006870-f5w6fw6q 1375 2 phase-3 phase-3 NNP cord-006870-f5w6fw6q 1375 3 trials trial NNS cord-006870-f5w6fw6q 1375 4 in in IN cord-006870-f5w6fw6q 1375 5 ICH ICH NNP cord-006870-f5w6fw6q 1375 6 have have VBP cord-006870-f5w6fw6q 1375 7 failed fail VBN cord-006870-f5w6fw6q 1375 8 to to TO cord-006870-f5w6fw6q 1375 9 demonstrate demonstrate VB cord-006870-f5w6fw6q 1375 10 improved improved JJ cord-006870-f5w6fw6q 1375 11 outcomes outcome NNS cord-006870-f5w6fw6q 1375 12 with with IN cord-006870-f5w6fw6q 1375 13 intensive intensive JJ cord-006870-f5w6fw6q 1375 14 systolic systolic JJ cord-006870-f5w6fw6q 1375 15 blood blood NN cord-006870-f5w6fw6q 1375 16 pressure pressure NN cord-006870-f5w6fw6q 1375 17 ( ( -LRB- cord-006870-f5w6fw6q 1375 18 BP BP NNP cord-006870-f5w6fw6q 1375 19 ) ) -RRB- cord-006870-f5w6fw6q 1375 20 lowering lowering NN cord-006870-f5w6fw6q 1375 21 . . . cord-006870-f5w6fw6q 1376 1 We -PRON- PRP cord-006870-f5w6fw6q 1376 2 sought seek VBD cord-006870-f5w6fw6q 1376 3 to to TO cord-006870-f5w6fw6q 1376 4 determine determine VB cord-006870-f5w6fw6q 1376 5 whether whether IN cord-006870-f5w6fw6q 1376 6 other other JJ cord-006870-f5w6fw6q 1376 7 BP BP NNP cord-006870-f5w6fw6q 1376 8 parameters parameter NNS cord-006870-f5w6fw6q 1376 9 - - : cord-006870-f5w6fw6q 1376 10 diastolic diastolic JJ cord-006870-f5w6fw6q 1376 11 BP BP NNP cord-006870-f5w6fw6q 1376 12 , , , cord-006870-f5w6fw6q 1376 13 pulse pulse NN cord-006870-f5w6fw6q 1376 14 pressure pressure NN cord-006870-f5w6fw6q 1376 15 ( ( -LRB- cord-006870-f5w6fw6q 1376 16 PP PP NNP cord-006870-f5w6fw6q 1376 17 ) ) -RRB- cord-006870-f5w6fw6q 1376 18 , , , cord-006870-f5w6fw6q 1376 19 and and CC cord-006870-f5w6fw6q 1376 20 mean mean VB cord-006870-f5w6fw6q 1376 21 arterial arterial JJ cord-006870-f5w6fw6q 1376 22 pressure pressure NN cord-006870-f5w6fw6q 1376 23 ( ( -LRB- cord-006870-f5w6fw6q 1376 24 MAP)-showed map)-showed RB cord-006870-f5w6fw6q 1376 25 an an DT cord-006870-f5w6fw6q 1376 26 association association NN cord-006870-f5w6fw6q 1376 27 with with IN cord-006870-f5w6fw6q 1376 28 clinical clinical JJ cord-006870-f5w6fw6q 1376 29 outcome outcome NN cord-006870-f5w6fw6q 1376 30 in in IN cord-006870-f5w6fw6q 1376 31 ICH ICH NNP cord-006870-f5w6fw6q 1376 32 . . . cord-006870-f5w6fw6q 1377 1 We -PRON- PRP cord-006870-f5w6fw6q 1377 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 1377 3 analyzed analyze VBD cord-006870-f5w6fw6q 1377 4 a a DT cord-006870-f5w6fw6q 1377 5 prospective prospective JJ cord-006870-f5w6fw6q 1377 6 cohort cohort NN cord-006870-f5w6fw6q 1377 7 of of IN cord-006870-f5w6fw6q 1377 8 672 672 CD cord-006870-f5w6fw6q 1377 9 patients patient NNS cord-006870-f5w6fw6q 1377 10 with with IN cord-006870-f5w6fw6q 1377 11 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1377 12 ICH ICH NNP cord-006870-f5w6fw6q 1377 13 and and CC cord-006870-f5w6fw6q 1377 14 documented document VBD cord-006870-f5w6fw6q 1377 15 demographic demographic JJ cord-006870-f5w6fw6q 1377 16 characteristics characteristic NNS cord-006870-f5w6fw6q 1377 17 , , , cord-006870-f5w6fw6q 1377 18 stroke stroke NN cord-006870-f5w6fw6q 1377 19 severity severity NN cord-006870-f5w6fw6q 1377 20 , , , cord-006870-f5w6fw6q 1377 21 and and CC cord-006870-f5w6fw6q 1377 22 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 1377 23 parameters parameter NNS cord-006870-f5w6fw6q 1377 24 . . . cord-006870-f5w6fw6q 1378 1 Consecutive consecutive JJ cord-006870-f5w6fw6q 1378 2 hourlyBP hourlyBP NNP cord-006870-f5w6fw6q 1378 3 recordings recording NNS cord-006870-f5w6fw6q 1378 4 allowed allow VBN cord-006870-f5w6fw6q 1378 5 for for IN cord-006870-f5w6fw6q 1378 6 computation computation NN cord-006870-f5w6fw6q 1378 7 of of IN cord-006870-f5w6fw6q 1378 8 systolic systolic JJ cord-006870-f5w6fw6q 1378 9 BP BP NNP cord-006870-f5w6fw6q 1378 10 , , , cord-006870-f5w6fw6q 1378 11 diastolic diastolic JJ cord-006870-f5w6fw6q 1378 12 BP BP NNP cord-006870-f5w6fw6q 1378 13 , , , cord-006870-f5w6fw6q 1378 14 PP PP NNP cord-006870-f5w6fw6q 1378 15 , , , cord-006870-f5w6fw6q 1378 16 and and CC cord-006870-f5w6fw6q 1378 17 MAP MAP NNP cord-006870-f5w6fw6q 1378 18 . . . cord-006870-f5w6fw6q 1379 1 Threshold threshold NN cord-006870-f5w6fw6q 1379 2 BP BP NNP cord-006870-f5w6fw6q 1379 3 values value NNS cord-006870-f5w6fw6q 1379 4 that that WDT cord-006870-f5w6fw6q 1379 5 transitioned transition VBD cord-006870-f5w6fw6q 1379 6 patients patient NNS cord-006870-f5w6fw6q 1379 7 from from IN cord-006870-f5w6fw6q 1379 8 survival survival NN cord-006870-f5w6fw6q 1379 9 to to IN cord-006870-f5w6fw6q 1379 10 death death NN cord-006870-f5w6fw6q 1379 11 were be VBD cord-006870-f5w6fw6q 1379 12 determined determine VBN cord-006870-f5w6fw6q 1379 13 from from IN cord-006870-f5w6fw6q 1379 14 ROC ROC NNP cord-006870-f5w6fw6q 1379 15 curves curve NNS cord-006870-f5w6fw6q 1379 16 . . . cord-006870-f5w6fw6q 1380 1 Using use VBG cord-006870-f5w6fw6q 1380 2 inhospital inhospital JJ cord-006870-f5w6fw6q 1380 3 mortality mortality NN cord-006870-f5w6fw6q 1380 4 as as IN cord-006870-f5w6fw6q 1380 5 outcome outcome NN cord-006870-f5w6fw6q 1380 6 , , , cord-006870-f5w6fw6q 1380 7 BP BP NNP cord-006870-f5w6fw6q 1380 8 parameters parameter NNS cord-006870-f5w6fw6q 1380 9 were be VBD cord-006870-f5w6fw6q 1380 10 evaluated evaluate VBN cord-006870-f5w6fw6q 1380 11 with with IN cord-006870-f5w6fw6q 1380 12 multivariable multivariable JJ cord-006870-f5w6fw6q 1380 13 logistic logistic JJ cord-006870-f5w6fw6q 1380 14 regression regression NN cord-006870-f5w6fw6q 1380 15 analysis analysis NN cord-006870-f5w6fw6q 1380 16 . . . cord-006870-f5w6fw6q 1381 1 Patients patient NNS cord-006870-f5w6fw6q 1381 2 who who WP cord-006870-f5w6fw6q 1381 3 died die VBD cord-006870-f5w6fw6q 1381 4 during during IN cord-006870-f5w6fw6q 1381 5 hospitalization hospitalization NN cord-006870-f5w6fw6q 1381 6 had have VBD cord-006870-f5w6fw6q 1382 1 higher high JJR cord-006870-f5w6fw6q 1382 2 mean mean JJ cord-006870-f5w6fw6q 1382 3 PP PP NNP cord-006870-f5w6fw6q 1383 1 compared compare VBN cord-006870-f5w6fw6q 1383 2 to to IN cord-006870-f5w6fw6q 1383 3 survivors survivor NNS cord-006870-f5w6fw6q 1383 4 ( ( -LRB- cord-006870-f5w6fw6q 1383 5 68.5 68.5 CD cord-006870-f5w6fw6q 1383 6 ±16.4mmHg ±16.4mmHg NNS cord-006870-f5w6fw6q 1383 7 vs. vs. FW cord-006870-f5w6fw6q 1383 8 65.4 65.4 CD cord-006870-f5w6fw6q 1383 9 ±12.4 ±12.4 NN cord-006870-f5w6fw6q 1383 10 mmHg mmHg NNS cord-006870-f5w6fw6q 1383 11 ; ; : cord-006870-f5w6fw6q 1383 12 p=0.032 p=0.032 ADD cord-006870-f5w6fw6q 1383 13 ) ) -RRB- cord-006870-f5w6fw6q 1383 14 . . . cord-006870-f5w6fw6q 1384 1 The the DT cord-006870-f5w6fw6q 1384 2 following following JJ cord-006870-f5w6fw6q 1384 3 admission admission NN cord-006870-f5w6fw6q 1384 4 variables variable NNS cord-006870-f5w6fw6q 1384 5 were be VBD cord-006870-f5w6fw6q 1384 6 associated associate VBN cord-006870-f5w6fw6q 1384 7 with with IN cord-006870-f5w6fw6q 1384 8 significantly significantly RB cord-006870-f5w6fw6q 1384 9 higher high JJR cord-006870-f5w6fw6q 1384 10 in in IN cord-006870-f5w6fw6q 1384 11 - - HYPH cord-006870-f5w6fw6q 1384 12 hospital hospital NN cord-006870-f5w6fw6q 1384 13 mortality mortality NN cord-006870-f5w6fw6q 1384 14 ( ( -LRB- cord-006870-f5w6fw6q 1384 15 p p NN cord-006870-f5w6fw6q 1384 16 < < XX cord-006870-f5w6fw6q 1384 17 0.001 0.001 CD cord-006870-f5w6fw6q 1384 18 ) ) -RRB- cord-006870-f5w6fw6q 1384 19 : : : cord-006870-f5w6fw6q 1384 20 poorer poor JJR cord-006870-f5w6fw6q 1384 21 admission admission NN cord-006870-f5w6fw6q 1384 22 clinical clinical JJ cord-006870-f5w6fw6q 1384 23 condition condition NN cord-006870-f5w6fw6q 1384 24 , , , cord-006870-f5w6fw6q 1384 25 intraventricular intraventricular JJ cord-006870-f5w6fw6q 1384 26 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1384 27 , , , cord-006870-f5w6fw6q 1384 28 and and CC cord-006870-f5w6fw6q 1384 29 increased increase VBN cord-006870-f5w6fw6q 1384 30 admission admission NN cord-006870-f5w6fw6q 1384 31 normalized normalize VBN cord-006870-f5w6fw6q 1384 32 hematoma hematoma NN cord-006870-f5w6fw6q 1384 33 volume volume NN cord-006870-f5w6fw6q 1384 34 . . . cord-006870-f5w6fw6q 1385 1 ROC ROC NNP cord-006870-f5w6fw6q 1385 2 analysis analysis NN cord-006870-f5w6fw6q 1385 3 showed show VBD cord-006870-f5w6fw6q 1385 4 that that IN cord-006870-f5w6fw6q 1385 5 mean mean JJ cord-006870-f5w6fw6q 1385 6 PP PP NNP cord-006870-f5w6fw6q 1385 7 dichotomized dichotomize VBD cord-006870-f5w6fw6q 1385 8 at at IN cord-006870-f5w6fw6q 1385 9 72.17 72.17 CD cord-006870-f5w6fw6q 1385 10 mmHg mmHg NNS cord-006870-f5w6fw6q 1385 11 , , , cord-006870-f5w6fw6q 1385 12 provided provide VBD cord-006870-f5w6fw6q 1385 13 a a DT cord-006870-f5w6fw6q 1385 14 transition transition NN cord-006870-f5w6fw6q 1385 15 point point NN cord-006870-f5w6fw6q 1385 16 that that WDT cord-006870-f5w6fw6q 1385 17 maximized maximize VBD cord-006870-f5w6fw6q 1385 18 sensitivity sensitivity NN cord-006870-f5w6fw6q 1385 19 and and CC cord-006870-f5w6fw6q 1385 20 specific specific JJ cord-006870-f5w6fw6q 1385 21 for for IN cord-006870-f5w6fw6q 1385 22 mortality mortality NN cord-006870-f5w6fw6q 1385 23 . . . cord-006870-f5w6fw6q 1386 1 The the DT cord-006870-f5w6fw6q 1386 2 association association NN cord-006870-f5w6fw6q 1386 3 of of IN cord-006870-f5w6fw6q 1386 4 this this DT cord-006870-f5w6fw6q 1386 5 increased increase VBD cord-006870-f5w6fw6q 1386 6 dichotomized dichotomize VBN cord-006870-f5w6fw6q 1386 7 PP PP NNP cord-006870-f5w6fw6q 1386 8 with with IN cord-006870-f5w6fw6q 1386 9 higher high JJR cord-006870-f5w6fw6q 1386 10 in in IN cord-006870-f5w6fw6q 1386 11 - - HYPH cord-006870-f5w6fw6q 1386 12 hospital hospital NN cord-006870-f5w6fw6q 1386 13 mortality mortality NN cord-006870-f5w6fw6q 1386 14 was be VBD cord-006870-f5w6fw6q 1386 15 maintained maintain VBN cord-006870-f5w6fw6q 1386 16 in in IN cord-006870-f5w6fw6q 1386 17 multivariable multivariable JJ cord-006870-f5w6fw6q 1386 18 logistic logistic JJ cord-006870-f5w6fw6q 1386 19 regression regression NN cord-006870-f5w6fw6q 1386 20 analysis analysis NN cord-006870-f5w6fw6q 1386 21 ( ( -LRB- cord-006870-f5w6fw6q 1386 22 OR or CC cord-006870-f5w6fw6q 1386 23 3.0 3.0 CD cord-006870-f5w6fw6q 1386 24 ; ; : cord-006870-f5w6fw6q 1386 25 95%CI 95%ci CD cord-006870-f5w6fw6q 1386 26 1.7 1.7 CD cord-006870-f5w6fw6q 1386 27 - - SYM cord-006870-f5w6fw6q 1386 28 5.3 5.3 CD cord-006870-f5w6fw6q 1386 29 ; ; : cord-006870-f5w6fw6q 1386 30 p p NN cord-006870-f5w6fw6q 1386 31 < < XX cord-006870-f5w6fw6q 1386 32 0.001 0.001 CD cord-006870-f5w6fw6q 1386 33 ) ) -RRB- cord-006870-f5w6fw6q 1386 34 adjusting adjust VBG cord-006870-f5w6fw6q 1386 35 for for IN cord-006870-f5w6fw6q 1386 36 potential potential JJ cord-006870-f5w6fw6q 1386 37 confounders confounder NNS cord-006870-f5w6fw6q 1386 38 . . . cord-006870-f5w6fw6q 1387 1 Widened widen VBN cord-006870-f5w6fw6q 1387 2 PP PP NNP cord-006870-f5w6fw6q 1387 3 may may MD cord-006870-f5w6fw6q 1387 4 be be VB cord-006870-f5w6fw6q 1387 5 an an DT cord-006870-f5w6fw6q 1387 6 independent independent JJ cord-006870-f5w6fw6q 1387 7 predictor predictor NN cord-006870-f5w6fw6q 1387 8 for for IN cord-006870-f5w6fw6q 1387 9 higher high JJR cord-006870-f5w6fw6q 1387 10 mortality mortality NN cord-006870-f5w6fw6q 1387 11 in in IN cord-006870-f5w6fw6q 1387 12 ICH ICH NNP cord-006870-f5w6fw6q 1387 13 . . . cord-006870-f5w6fw6q 1388 1 This this DT cord-006870-f5w6fw6q 1388 2 association association NN cord-006870-f5w6fw6q 1388 3 requires require VBZ cord-006870-f5w6fw6q 1388 4 further further JJ cord-006870-f5w6fw6q 1388 5 study study NN cord-006870-f5w6fw6q 1388 6 . . . cord-006870-f5w6fw6q 1389 1 A a DT cord-006870-f5w6fw6q 1389 2 National National NNP cord-006870-f5w6fw6q 1389 3 Confidential Confidential NNP cord-006870-f5w6fw6q 1389 4 Enquiry Enquiry NNP cord-006870-f5w6fw6q 1389 5 into into IN cord-006870-f5w6fw6q 1389 6 Patient Patient NNP cord-006870-f5w6fw6q 1389 7 Outcome outcome NN cord-006870-f5w6fw6q 1389 8 and and CC cord-006870-f5w6fw6q 1389 9 Death death NN cord-006870-f5w6fw6q 1389 10 ( ( -LRB- cord-006870-f5w6fw6q 1389 11 NCEPOD NCEPOD NNP cord-006870-f5w6fw6q 1389 12 ) ) -RRB- cord-006870-f5w6fw6q 1389 13 report report NN cord-006870-f5w6fw6q 1389 14 concerning concern VBG cord-006870-f5w6fw6q 1389 15 management management NN cord-006870-f5w6fw6q 1389 16 of of IN cord-006870-f5w6fw6q 1389 17 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 1389 18 subarachnoid subarachnoid NNP cord-006870-f5w6fw6q 1389 19 haemorrhages haemorrhage NNS cord-006870-f5w6fw6q 1389 20 in in IN cord-006870-f5w6fw6q 1389 21 the the DT cord-006870-f5w6fw6q 1389 22 UK UK NNP cord-006870-f5w6fw6q 1389 23 suggested suggest VBD cord-006870-f5w6fw6q 1389 24 up up RP cord-006870-f5w6fw6q 1389 25 to to IN cord-006870-f5w6fw6q 1389 26 half half NN cord-006870-f5w6fw6q 1389 27 of of IN cord-006870-f5w6fw6q 1389 28 patients patient NNS cord-006870-f5w6fw6q 1389 29 received receive VBD cord-006870-f5w6fw6q 1389 30 suboptimal suboptimal JJ cord-006870-f5w6fw6q 1389 31 consideration consideration NN cord-006870-f5w6fw6q 1389 32 for for IN cord-006870-f5w6fw6q 1389 33 organ organ NN cord-006870-f5w6fw6q 1389 34 donation donation NN cord-006870-f5w6fw6q 1389 35 . . . cord-006870-f5w6fw6q 1390 1 As as IN cord-006870-f5w6fw6q 1390 2 demand demand NN cord-006870-f5w6fw6q 1390 3 for for IN cord-006870-f5w6fw6q 1390 4 organs organ NNS cord-006870-f5w6fw6q 1390 5 continues continue VBZ cord-006870-f5w6fw6q 1390 6 to to TO cord-006870-f5w6fw6q 1390 7 increase increase VB cord-006870-f5w6fw6q 1390 8 , , , cord-006870-f5w6fw6q 1390 9 so so RB cord-006870-f5w6fw6q 1390 10 does do VBZ cord-006870-f5w6fw6q 1390 11 the the DT cord-006870-f5w6fw6q 1390 12 need need NN cord-006870-f5w6fw6q 1390 13 to to TO cord-006870-f5w6fw6q 1390 14 pursue pursue VB cord-006870-f5w6fw6q 1390 15 all all DT cord-006870-f5w6fw6q 1390 16 potential potential JJ cord-006870-f5w6fw6q 1390 17 sources source NNS cord-006870-f5w6fw6q 1390 18 of of IN cord-006870-f5w6fw6q 1390 19 donor donor NN cord-006870-f5w6fw6q 1390 20 organs organ NNS cord-006870-f5w6fw6q 1390 21 . . . cord-006870-f5w6fw6q 1391 1 Subarachnoid subarachnoid NN cord-006870-f5w6fw6q 1391 2 haemorrhages haemorrhage NNS cord-006870-f5w6fw6q 1391 3 have have VBP cord-006870-f5w6fw6q 1391 4 an an DT cord-006870-f5w6fw6q 1391 5 estimated estimate VBN cord-006870-f5w6fw6q 1391 6 mortality mortality NN cord-006870-f5w6fw6q 1391 7 of of IN cord-006870-f5w6fw6q 1391 8 50 50 CD cord-006870-f5w6fw6q 1391 9 % % NN cord-006870-f5w6fw6q 1391 10 and and CC cord-006870-f5w6fw6q 1391 11 can can MD cord-006870-f5w6fw6q 1391 12 potentially potentially RB cord-006870-f5w6fw6q 1391 13 provide provide VB cord-006870-f5w6fw6q 1391 14 younger young JJR cord-006870-f5w6fw6q 1391 15 donor donor NN cord-006870-f5w6fw6q 1391 16 organs organ NNS cord-006870-f5w6fw6q 1391 17 with with IN cord-006870-f5w6fw6q 1391 18 less less RBR cord-006870-f5w6fw6q 1391 19 chronic chronic JJ cord-006870-f5w6fw6q 1391 20 pathology pathology NN cord-006870-f5w6fw6q 1391 21 . . . cord-006870-f5w6fw6q 1392 1 This this DT cord-006870-f5w6fw6q 1392 2 is be VBZ cord-006870-f5w6fw6q 1392 3 a a DT cord-006870-f5w6fw6q 1392 4 comprehensive comprehensive JJ cord-006870-f5w6fw6q 1392 5 picture picture NN cord-006870-f5w6fw6q 1392 6 of of IN cord-006870-f5w6fw6q 1392 7 donation donation NN cord-006870-f5w6fw6q 1392 8 rates rate NNS cord-006870-f5w6fw6q 1392 9 within within IN cord-006870-f5w6fw6q 1392 10 a a DT cord-006870-f5w6fw6q 1392 11 tertiary tertiary JJ cord-006870-f5w6fw6q 1392 12 centre centre NN cord-006870-f5w6fw6q 1392 13 . . . cord-006870-f5w6fw6q 1393 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 1393 2 data datum NNS cord-006870-f5w6fw6q 1393 3 regarding regard VBG cord-006870-f5w6fw6q 1393 4 all all DT cord-006870-f5w6fw6q 1393 5 deceased deceased JJ cord-006870-f5w6fw6q 1393 6 patients patient NNS cord-006870-f5w6fw6q 1393 7 on on IN cord-006870-f5w6fw6q 1393 8 the the DT cord-006870-f5w6fw6q 1393 9 Neuro Neuro NNP cord-006870-f5w6fw6q 1393 10 - - HYPH cord-006870-f5w6fw6q 1393 11 Intensive Intensive NNP cord-006870-f5w6fw6q 1393 12 Care Care NNP cord-006870-f5w6fw6q 1393 13 Unit Unit NNP cord-006870-f5w6fw6q 1393 14 during during IN cord-006870-f5w6fw6q 1393 15 2016 2016 CD cord-006870-f5w6fw6q 1393 16 with with IN cord-006870-f5w6fw6q 1393 17 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 1393 18 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 1393 19 haemorrhage haemorrhage NN cord-006870-f5w6fw6q 1393 20 as as IN cord-006870-f5w6fw6q 1393 21 the the DT cord-006870-f5w6fw6q 1393 22 cause cause NN cord-006870-f5w6fw6q 1393 23 of of IN cord-006870-f5w6fw6q 1393 24 death death NN cord-006870-f5w6fw6q 1393 25 was be VBD cord-006870-f5w6fw6q 1393 26 obtained obtain VBN cord-006870-f5w6fw6q 1393 27 from from IN cord-006870-f5w6fw6q 1393 28 the the DT cord-006870-f5w6fw6q 1393 29 NHS NHS NNP cord-006870-f5w6fw6q 1393 30 Blood Blood NNP cord-006870-f5w6fw6q 1393 31 and and CC cord-006870-f5w6fw6q 1393 32 Transfusion Transfusion NNP cord-006870-f5w6fw6q 1393 33 team team NN cord-006870-f5w6fw6q 1393 34 . . . cord-006870-f5w6fw6q 1394 1 The the DT cord-006870-f5w6fw6q 1394 2 local local JJ cord-006870-f5w6fw6q 1394 3 audit audit NN cord-006870-f5w6fw6q 1394 4 committee committee NN cord-006870-f5w6fw6q 1394 5 provided provide VBD cord-006870-f5w6fw6q 1394 6 ethical ethical JJ cord-006870-f5w6fw6q 1394 7 approval approval NN cord-006870-f5w6fw6q 1394 8 . . . cord-006870-f5w6fw6q 1395 1 Data datum NNS cord-006870-f5w6fw6q 1395 2 regarding regard VBG cord-006870-f5w6fw6q 1395 3 organ organ NN cord-006870-f5w6fw6q 1395 4 donation donation NN cord-006870-f5w6fw6q 1395 5 was be VBD cord-006870-f5w6fw6q 1395 6 extracted extract VBN cord-006870-f5w6fw6q 1395 7 and and CC cord-006870-f5w6fw6q 1395 8 compared compare VBN cord-006870-f5w6fw6q 1395 9 to to IN cord-006870-f5w6fw6q 1395 10 national national JJ cord-006870-f5w6fw6q 1395 11 data datum NNS cord-006870-f5w6fw6q 1395 12 , , , cord-006870-f5w6fw6q 1395 13 then then RB cord-006870-f5w6fw6q 1395 14 analysed analyse VBD cord-006870-f5w6fw6q 1395 15 using use VBG cord-006870-f5w6fw6q 1395 16 Fisher Fisher NNP cord-006870-f5w6fw6q 1395 17 's 's POS cord-006870-f5w6fw6q 1395 18 Exact Exact NNP cord-006870-f5w6fw6q 1395 19 Test test NN cord-006870-f5w6fw6q 1395 20 . . . cord-006870-f5w6fw6q 1396 1 Referral referral NN cord-006870-f5w6fw6q 1396 2 rates rate NNS cord-006870-f5w6fw6q 1396 3 were be VBD cord-006870-f5w6fw6q 1396 4 100 100 CD cord-006870-f5w6fw6q 1396 5 % % NN cord-006870-f5w6fw6q 1396 6 . . . cord-006870-f5w6fw6q 1397 1 This this DT cord-006870-f5w6fw6q 1397 2 is be VBZ cord-006870-f5w6fw6q 1397 3 greater great JJR cord-006870-f5w6fw6q 1397 4 than than IN cord-006870-f5w6fw6q 1397 5 the the DT cord-006870-f5w6fw6q 1397 6 national national JJ cord-006870-f5w6fw6q 1397 7 average average NN cord-006870-f5w6fw6q 1397 8 of of IN cord-006870-f5w6fw6q 1397 9 57.7 57.7 CD cord-006870-f5w6fw6q 1397 10 % % NN cord-006870-f5w6fw6q 1397 11 ( ( -LRB- cord-006870-f5w6fw6q 1397 12 p=0.001 p=0.001 NNP cord-006870-f5w6fw6q 1397 13 ) ) -RRB- cord-006870-f5w6fw6q 1397 14 , , , cord-006870-f5w6fw6q 1397 15 yet yet CC cord-006870-f5w6fw6q 1397 16 only only RB cord-006870-f5w6fw6q 1397 17 30.8 30.8 CD cord-006870-f5w6fw6q 1397 18 % % NN cord-006870-f5w6fw6q 1397 19 of of IN cord-006870-f5w6fw6q 1397 20 referred refer VBN cord-006870-f5w6fw6q 1397 21 patients patient NNS cord-006870-f5w6fw6q 1397 22 proceeded proceed VBD cord-006870-f5w6fw6q 1397 23 to to IN cord-006870-f5w6fw6q 1397 24 organ organ NN cord-006870-f5w6fw6q 1397 25 donation donation NN cord-006870-f5w6fw6q 1397 26 . . . cord-006870-f5w6fw6q 1398 1 Consent consent NN cord-006870-f5w6fw6q 1398 2 was be VBD cord-006870-f5w6fw6q 1398 3 withheld withhold VBN cord-006870-f5w6fw6q 1398 4 in in IN cord-006870-f5w6fw6q 1398 5 52.8 52.8 CD cord-006870-f5w6fw6q 1398 6 % % NN cord-006870-f5w6fw6q 1398 7 of of IN cord-006870-f5w6fw6q 1398 8 potential potential JJ cord-006870-f5w6fw6q 1398 9 donors donor NNS cord-006870-f5w6fw6q 1398 10 . . . cord-006870-f5w6fw6q 1399 1 Nationally nationally RB cord-006870-f5w6fw6q 1399 2 37.9 37.9 CD cord-006870-f5w6fw6q 1399 3 % % NN cord-006870-f5w6fw6q 1399 4 of of IN cord-006870-f5w6fw6q 1399 5 donors donor NNS cord-006870-f5w6fw6q 1399 6 are be VBP cord-006870-f5w6fw6q 1399 7 lost lose VBN cord-006870-f5w6fw6q 1399 8 due due IN cord-006870-f5w6fw6q 1399 9 to to IN cord-006870-f5w6fw6q 1399 10 non non JJ cord-006870-f5w6fw6q 1399 11 - - JJ cord-006870-f5w6fw6q 1399 12 consent consent JJ cord-006870-f5w6fw6q 1399 13 ( ( -LRB- cord-006870-f5w6fw6q 1399 14 p=0.235 p=0.235 NNP cord-006870-f5w6fw6q 1399 15 ) ) -RRB- cord-006870-f5w6fw6q 1399 16 . . . cord-006870-f5w6fw6q 1400 1 32.1 32.1 CD cord-006870-f5w6fw6q 1400 2 % % NN cord-006870-f5w6fw6q 1400 3 of of IN cord-006870-f5w6fw6q 1400 4 consented consent VBN cord-006870-f5w6fw6q 1400 5 patients patient NNS cord-006870-f5w6fw6q 1400 6 were be VBD cord-006870-f5w6fw6q 1400 7 unable unable JJ cord-006870-f5w6fw6q 1400 8 to to TO cord-006870-f5w6fw6q 1400 9 donate donate VB cord-006870-f5w6fw6q 1400 10 organs organ NNS cord-006870-f5w6fw6q 1400 11 , , , cord-006870-f5w6fw6q 1400 12 similar similar JJ cord-006870-f5w6fw6q 1400 13 to to IN cord-006870-f5w6fw6q 1400 14 national national JJ cord-006870-f5w6fw6q 1400 15 figures figure NNS cord-006870-f5w6fw6q 1400 16 ( ( -LRB- cord-006870-f5w6fw6q 1400 17 p=1.00 p=1.00 NNP cord-006870-f5w6fw6q 1400 18 ) ) -RRB- cord-006870-f5w6fw6q 1400 19 . . . cord-006870-f5w6fw6q 1401 1 Referral referral NN cord-006870-f5w6fw6q 1401 2 rates rate NNS cord-006870-f5w6fw6q 1401 3 within within IN cord-006870-f5w6fw6q 1401 4 this this DT cord-006870-f5w6fw6q 1401 5 centre centre NN cord-006870-f5w6fw6q 1401 6 are be VBP cord-006870-f5w6fw6q 1401 7 excellent excellent JJ cord-006870-f5w6fw6q 1401 8 ; ; : cord-006870-f5w6fw6q 1401 9 consent consent NN cord-006870-f5w6fw6q 1401 10 remains remain VBZ cord-006870-f5w6fw6q 1401 11 the the DT cord-006870-f5w6fw6q 1401 12 main main JJ cord-006870-f5w6fw6q 1401 13 obstacle obstacle NN cord-006870-f5w6fw6q 1401 14 . . . cord-006870-f5w6fw6q 1402 1 Consent consent NN cord-006870-f5w6fw6q 1402 2 rates rate NNS cord-006870-f5w6fw6q 1402 3 can can MD cord-006870-f5w6fw6q 1402 4 be be VB cord-006870-f5w6fw6q 1402 5 improved improve VBN cord-006870-f5w6fw6q 1402 6 using use VBG cord-006870-f5w6fw6q 1402 7 a a DT cord-006870-f5w6fw6q 1402 8 long long JJ cord-006870-f5w6fw6q 1402 9 contact contact NN cord-006870-f5w6fw6q 1402 10 model model NN cord-006870-f5w6fw6q 1402 11 where where WRB cord-006870-f5w6fw6q 1402 12 specialist specialist NN cord-006870-f5w6fw6q 1402 13 nurses nurse NNS cord-006870-f5w6fw6q 1402 14 in in IN cord-006870-f5w6fw6q 1402 15 organ organ NN cord-006870-f5w6fw6q 1402 16 donation donation NN cord-006870-f5w6fw6q 1402 17 establish establish VB cord-006870-f5w6fw6q 1402 18 relationships relationship NNS cord-006870-f5w6fw6q 1402 19 with with IN cord-006870-f5w6fw6q 1402 20 relatives relative NNS cord-006870-f5w6fw6q 1402 21 prior prior RB cord-006870-f5w6fw6q 1402 22 to to IN cord-006870-f5w6fw6q 1402 23 any any DT cord-006870-f5w6fw6q 1402 24 discussion discussion NN cord-006870-f5w6fw6q 1402 25 of of IN cord-006870-f5w6fw6q 1402 26 donation donation NN cord-006870-f5w6fw6q 1402 27 . . . cord-006870-f5w6fw6q 1403 1 The the DT cord-006870-f5w6fw6q 1403 2 ideal ideal JJ cord-006870-f5w6fw6q 1403 3 discussion discussion NN cord-006870-f5w6fw6q 1403 4 is be VBZ cord-006870-f5w6fw6q 1403 5 a a DT cord-006870-f5w6fw6q 1403 6 pre pre JJ cord-006870-f5w6fw6q 1403 7 - - JJ cord-006870-f5w6fw6q 1403 8 planned planned JJ cord-006870-f5w6fw6q 1403 9 collaboration collaboration NN cord-006870-f5w6fw6q 1403 10 involving involve VBG cord-006870-f5w6fw6q 1403 11 a a DT cord-006870-f5w6fw6q 1403 12 senior senior JJ cord-006870-f5w6fw6q 1403 13 doctor doctor NN cord-006870-f5w6fw6q 1403 14 and and CC cord-006870-f5w6fw6q 1403 15 a a DT cord-006870-f5w6fw6q 1403 16 specialist specialist JJ cord-006870-f5w6fw6q 1403 17 nurse nurse NN cord-006870-f5w6fw6q 1403 18 . . . cord-006870-f5w6fw6q 1404 1 Early early JJ cord-006870-f5w6fw6q 1404 2 brain brain NN cord-006870-f5w6fw6q 1404 3 stem stem NN cord-006870-f5w6fw6q 1404 4 testing testing NN cord-006870-f5w6fw6q 1404 5 may may MD cord-006870-f5w6fw6q 1404 6 facilitate facilitate VB cord-006870-f5w6fw6q 1404 7 earlier early JJR cord-006870-f5w6fw6q 1404 8 acceptance acceptance NN cord-006870-f5w6fw6q 1404 9 of of IN cord-006870-f5w6fw6q 1404 10 death death NN cord-006870-f5w6fw6q 1404 11 by by IN cord-006870-f5w6fw6q 1404 12 relatives relative NNS cord-006870-f5w6fw6q 1404 13 whilst whilst IN cord-006870-f5w6fw6q 1404 14 reducing reduce VBG cord-006870-f5w6fw6q 1404 15 the the DT cord-006870-f5w6fw6q 1404 16 duration duration NN cord-006870-f5w6fw6q 1404 17 of of IN cord-006870-f5w6fw6q 1404 18 the the DT cord-006870-f5w6fw6q 1404 19 multi multi JJ cord-006870-f5w6fw6q 1404 20 - - JJ cord-006870-f5w6fw6q 1404 21 systemic systemic JJ cord-006870-f5w6fw6q 1404 22 effects effect NNS cord-006870-f5w6fw6q 1404 23 of of IN cord-006870-f5w6fw6q 1404 24 the the DT cord-006870-f5w6fw6q 1404 25 associated associate VBN cord-006870-f5w6fw6q 1404 26 hyperresponsive hyperresponsive NNP cord-006870-f5w6fw6q 1404 27 cascade cascade NN cord-006870-f5w6fw6q 1404 28 on on IN cord-006870-f5w6fw6q 1404 29 donor donor NN cord-006870-f5w6fw6q 1404 30 organs organ NNS cord-006870-f5w6fw6q 1404 31 . . . cord-006870-f5w6fw6q 1405 1 Neurosurgeons neurosurgeon NNS cord-006870-f5w6fw6q 1405 2 should should MD cord-006870-f5w6fw6q 1405 3 be be VB cord-006870-f5w6fw6q 1405 4 encouraged encourage VBN cord-006870-f5w6fw6q 1405 5 to to TO cord-006870-f5w6fw6q 1405 6 suggest suggest VB cord-006870-f5w6fw6q 1405 7 organ organ NN cord-006870-f5w6fw6q 1405 8 donation donation NN cord-006870-f5w6fw6q 1405 9 when when WRB cord-006870-f5w6fw6q 1405 10 declining decline VBG cord-006870-f5w6fw6q 1405 11 referrals referral NNS cord-006870-f5w6fw6q 1405 12 . . . cord-006870-f5w6fw6q 1406 1 Further further JJ cord-006870-f5w6fw6q 1406 2 work work NN cord-006870-f5w6fw6q 1406 3 is be VBZ cord-006870-f5w6fw6q 1406 4 needed need VBN cord-006870-f5w6fw6q 1406 5 to to TO cord-006870-f5w6fw6q 1406 6 assess assess VB cord-006870-f5w6fw6q 1406 7 the the DT cord-006870-f5w6fw6q 1406 8 barriers barrier NNS cord-006870-f5w6fw6q 1406 9 to to IN cord-006870-f5w6fw6q 1406 10 instituting institute VBG cord-006870-f5w6fw6q 1406 11 these these DT cord-006870-f5w6fw6q 1406 12 measures measure NNS cord-006870-f5w6fw6q 1406 13 and and CC cord-006870-f5w6fw6q 1406 14 inspiring inspiring JJ cord-006870-f5w6fw6q 1406 15 change change NN cord-006870-f5w6fw6q 1406 16 . . . cord-006870-f5w6fw6q 1407 1 Spontaneous spontaneous JJ cord-006870-f5w6fw6q 1407 2 brainstem brainstem NN cord-006870-f5w6fw6q 1407 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1407 4 has have VBZ cord-006870-f5w6fw6q 1407 5 been be VBN cord-006870-f5w6fw6q 1407 6 historically historically RB cord-006870-f5w6fw6q 1407 7 associated associate VBN cord-006870-f5w6fw6q 1407 8 with with IN cord-006870-f5w6fw6q 1407 9 high high JJ cord-006870-f5w6fw6q 1407 10 mortality mortality NN cord-006870-f5w6fw6q 1407 11 . . . cord-006870-f5w6fw6q 1408 1 However however RB cord-006870-f5w6fw6q 1408 2 , , , cord-006870-f5w6fw6q 1408 3 updated update VBN cord-006870-f5w6fw6q 1408 4 data datum NNS cord-006870-f5w6fw6q 1408 5 on on IN cord-006870-f5w6fw6q 1408 6 the the DT cord-006870-f5w6fw6q 1408 7 frequency frequency NN cord-006870-f5w6fw6q 1408 8 and and CC cord-006870-f5w6fw6q 1408 9 outcome outcome NN cord-006870-f5w6fw6q 1408 10 of of IN cord-006870-f5w6fw6q 1408 11 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1408 12 brainstem brainstem NN cord-006870-f5w6fw6q 1408 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1408 14 is be VBZ cord-006870-f5w6fw6q 1408 15 scarce scarce JJ cord-006870-f5w6fw6q 1408 16 vis vis FW cord-006870-f5w6fw6q 1408 17 - - HYPH cord-006870-f5w6fw6q 1408 18 a a FW cord-006870-f5w6fw6q 1408 19 - - HYPH cord-006870-f5w6fw6q 1408 20 vis vis FW cord-006870-f5w6fw6q 1408 21 advances advance NNS cord-006870-f5w6fw6q 1408 22 in in IN cord-006870-f5w6fw6q 1408 23 neuro neuro NNP cord-006870-f5w6fw6q 1408 24 - - HYPH cord-006870-f5w6fw6q 1408 25 critical critical JJ cord-006870-f5w6fw6q 1408 26 care care NN cord-006870-f5w6fw6q 1408 27 . . . cord-006870-f5w6fw6q 1409 1 The the DT cord-006870-f5w6fw6q 1409 2 purpose purpose NN cord-006870-f5w6fw6q 1409 3 of of IN cord-006870-f5w6fw6q 1409 4 this this DT cord-006870-f5w6fw6q 1409 5 study study NN cord-006870-f5w6fw6q 1409 6 was be VBD cord-006870-f5w6fw6q 1409 7 to to TO cord-006870-f5w6fw6q 1409 8 investigate investigate VB cord-006870-f5w6fw6q 1409 9 the the DT cord-006870-f5w6fw6q 1409 10 frequency frequency NN cord-006870-f5w6fw6q 1409 11 and and CC cord-006870-f5w6fw6q 1409 12 outcome outcome NN cord-006870-f5w6fw6q 1409 13 of of IN cord-006870-f5w6fw6q 1409 14 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1409 15 brainstem brainstem NN cord-006870-f5w6fw6q 1409 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1409 17 . . . cord-006870-f5w6fw6q 1410 1 Records record NNS cord-006870-f5w6fw6q 1410 2 of of IN cord-006870-f5w6fw6q 1410 3 consecutive consecutive JJ cord-006870-f5w6fw6q 1410 4 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1410 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1410 6 ( ( -LRB- cord-006870-f5w6fw6q 1410 7 ICH ICH NNP cord-006870-f5w6fw6q 1410 8 ) ) -RRB- cord-006870-f5w6fw6q 1410 9 patients patient NNS cord-006870-f5w6fw6q 1410 10 presenting present VBG cord-006870-f5w6fw6q 1410 11 to to IN cord-006870-f5w6fw6q 1410 12 an an DT cord-006870-f5w6fw6q 1410 13 urban urban JJ cord-006870-f5w6fw6q 1410 14 academic academic JJ cord-006870-f5w6fw6q 1410 15 medical medical JJ cord-006870-f5w6fw6q 1410 16 center center NN cord-006870-f5w6fw6q 1410 17 from from IN cord-006870-f5w6fw6q 1410 18 January January NNP cord-006870-f5w6fw6q 1410 19 2010 2010 CD cord-006870-f5w6fw6q 1410 20 though though IN cord-006870-f5w6fw6q 1410 21 December December NNP cord-006870-f5w6fw6q 1410 22 2015 2015 CD cord-006870-f5w6fw6q 1410 23 were be VBD cord-006870-f5w6fw6q 1410 24 reviewed review VBN cord-006870-f5w6fw6q 1410 25 . . . cord-006870-f5w6fw6q 1411 1 Cases case NNS cord-006870-f5w6fw6q 1411 2 with with IN cord-006870-f5w6fw6q 1411 3 brainstem brainstem NN cord-006870-f5w6fw6q 1411 4 hematomas hematoma NNS cord-006870-f5w6fw6q 1411 5 were be VBD cord-006870-f5w6fw6q 1411 6 isolated isolate VBN cord-006870-f5w6fw6q 1411 7 for for IN cord-006870-f5w6fw6q 1411 8 analysis analysis NN cord-006870-f5w6fw6q 1411 9 . . . cord-006870-f5w6fw6q 1412 1 Data datum NNS cord-006870-f5w6fw6q 1412 2 on on IN cord-006870-f5w6fw6q 1412 3 demographics demographic NNS cord-006870-f5w6fw6q 1412 4 and and CC cord-006870-f5w6fw6q 1412 5 outcomes outcome NNS cord-006870-f5w6fw6q 1412 6 were be VBD cord-006870-f5w6fw6q 1412 7 collected collect VBN cord-006870-f5w6fw6q 1412 8 and and CC cord-006870-f5w6fw6q 1412 9 analyzed analyze VBN cord-006870-f5w6fw6q 1412 10 . . . cord-006870-f5w6fw6q 1413 1 Sub sub JJ cord-006870-f5w6fw6q 1413 2 - - JJ cord-006870-f5w6fw6q 1413 3 group group NN cord-006870-f5w6fw6q 1413 4 analysis analysis NN cord-006870-f5w6fw6q 1413 5 was be VBD cord-006870-f5w6fw6q 1413 6 also also RB cord-006870-f5w6fw6q 1413 7 done do VBN cord-006870-f5w6fw6q 1413 8 to to TO cord-006870-f5w6fw6q 1413 9 look look VB cord-006870-f5w6fw6q 1413 10 at at IN cord-006870-f5w6fw6q 1413 11 outcomes outcome NNS cord-006870-f5w6fw6q 1413 12 based base VBN cord-006870-f5w6fw6q 1413 13 on on IN cord-006870-f5w6fw6q 1413 14 location location NN cord-006870-f5w6fw6q 1413 15 of of IN cord-006870-f5w6fw6q 1413 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1413 17 in in IN cord-006870-f5w6fw6q 1413 18 the the DT cord-006870-f5w6fw6q 1413 19 brainstem brainstem NN cord-006870-f5w6fw6q 1413 20 . . . cord-006870-f5w6fw6q 1414 1 Of of IN cord-006870-f5w6fw6q 1414 2 181 181 CD cord-006870-f5w6fw6q 1414 3 consecutive consecutive JJ cord-006870-f5w6fw6q 1414 4 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1414 5 ICH ICH NNP cord-006870-f5w6fw6q 1414 6 patients patient NNS cord-006870-f5w6fw6q 1414 7 , , , cord-006870-f5w6fw6q 1414 8 13 13 CD cord-006870-f5w6fw6q 1414 9 ( ( -LRB- cord-006870-f5w6fw6q 1414 10 7.18 7.18 CD cord-006870-f5w6fw6q 1414 11 % % NN cord-006870-f5w6fw6q 1414 12 ) ) -RRB- cord-006870-f5w6fw6q 1414 13 presented present VBN cord-006870-f5w6fw6q 1414 14 with with IN cord-006870-f5w6fw6q 1414 15 brainstem brainstem NN cord-006870-f5w6fw6q 1414 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1414 17 ; ; : cord-006870-f5w6fw6q 1414 18 7 7 CD cord-006870-f5w6fw6q 1414 19 ( ( -LRB- cord-006870-f5w6fw6q 1414 20 53.8 53.8 CD cord-006870-f5w6fw6q 1414 21 % % NN cord-006870-f5w6fw6q 1414 22 ) ) -RRB- cord-006870-f5w6fw6q 1414 23 were be VBD cord-006870-f5w6fw6q 1414 24 pontine pontine JJ cord-006870-f5w6fw6q 1414 25 , , , cord-006870-f5w6fw6q 1414 26 2 2 CD cord-006870-f5w6fw6q 1414 27 ( ( -LRB- cord-006870-f5w6fw6q 1414 28 15.4 15.4 CD cord-006870-f5w6fw6q 1414 29 % % NN cord-006870-f5w6fw6q 1414 30 ) ) -RRB- cord-006870-f5w6fw6q 1414 31 mesencephalic mesencephalic NNP cord-006870-f5w6fw6q 1414 32 , , , cord-006870-f5w6fw6q 1414 33 and and CC cord-006870-f5w6fw6q 1414 34 4 4 CD cord-006870-f5w6fw6q 1414 35 ( ( -LRB- cord-006870-f5w6fw6q 1414 36 30.8 30.8 CD cord-006870-f5w6fw6q 1414 37 % % NN cord-006870-f5w6fw6q 1414 38 ) ) -RRB- cord-006870-f5w6fw6q 1414 39 were be VBD cord-006870-f5w6fw6q 1414 40 located locate VBN cord-006870-f5w6fw6q 1414 41 in in IN cord-006870-f5w6fw6q 1414 42 both both CC cord-006870-f5w6fw6q 1414 43 the the DT cord-006870-f5w6fw6q 1414 44 pons pon NNS cord-006870-f5w6fw6q 1414 45 and and CC cord-006870-f5w6fw6q 1414 46 the the DT cord-006870-f5w6fw6q 1414 47 midbrain midbrain NN cord-006870-f5w6fw6q 1414 48 . . . cord-006870-f5w6fw6q 1415 1 The the DT cord-006870-f5w6fw6q 1415 2 average average JJ cord-006870-f5w6fw6q 1415 3 age age NN cord-006870-f5w6fw6q 1415 4 was be VBD cord-006870-f5w6fw6q 1415 5 52.92 52.92 CD cord-006870-f5w6fw6q 1415 6 years year NNS cord-006870-f5w6fw6q 1415 7 and and CC cord-006870-f5w6fw6q 1415 8 ( ( -LRB- cord-006870-f5w6fw6q 1415 9 38.46 38.46 CD cord-006870-f5w6fw6q 1415 10 % % NN cord-006870-f5w6fw6q 1415 11 ) ) -RRB- cord-006870-f5w6fw6q 1415 12 were be VBD cord-006870-f5w6fw6q 1415 13 men man NNS cord-006870-f5w6fw6q 1415 14 . . . cord-006870-f5w6fw6q 1416 1 Median Median NNP cord-006870-f5w6fw6q 1416 2 Glasgow Glasgow NNP cord-006870-f5w6fw6q 1416 3 Coma Coma NNP cord-006870-f5w6fw6q 1416 4 Scale Scale NNP cord-006870-f5w6fw6q 1416 5 on on IN cord-006870-f5w6fw6q 1416 6 presentation presentation NN cord-006870-f5w6fw6q 1416 7 was be VBD cord-006870-f5w6fw6q 1416 8 6.5 6.5 CD cord-006870-f5w6fw6q 1416 9 . . . cord-006870-f5w6fw6q 1417 1 Thirty thirty CD cord-006870-f5w6fw6q 1417 2 - - HYPH cord-006870-f5w6fw6q 1417 3 day day NN cord-006870-f5w6fw6q 1417 4 mortality mortality NN cord-006870-f5w6fw6q 1417 5 rate rate NN cord-006870-f5w6fw6q 1417 6 was be VBD cord-006870-f5w6fw6q 1417 7 62.5 62.5 CD cord-006870-f5w6fw6q 1417 8 % % NN cord-006870-f5w6fw6q 1417 9 , , , cord-006870-f5w6fw6q 1417 10 with with IN cord-006870-f5w6fw6q 1417 11 6 6 CD cord-006870-f5w6fw6q 1417 12 in in IN cord-006870-f5w6fw6q 1417 13 - - HYPH cord-006870-f5w6fw6q 1417 14 hospital hospital NN cord-006870-f5w6fw6q 1417 15 deaths death NNS cord-006870-f5w6fw6q 1417 16 and and CC cord-006870-f5w6fw6q 1417 17 2 2 CD cord-006870-f5w6fw6q 1417 18 deaths death NNS cord-006870-f5w6fw6q 1417 19 post post VBP cord-006870-f5w6fw6q 1417 20 discharge discharge NN cord-006870-f5w6fw6q 1417 21 . . . cord-006870-f5w6fw6q 1418 1 Two two CD cord-006870-f5w6fw6q 1418 2 and and CC cord-006870-f5w6fw6q 1418 3 3 3 CD cord-006870-f5w6fw6q 1418 4 patients patient NNS cord-006870-f5w6fw6q 1418 5 were be VBD cord-006870-f5w6fw6q 1418 6 discharged discharge VBN cord-006870-f5w6fw6q 1418 7 home home RB cord-006870-f5w6fw6q 1418 8 or or CC cord-006870-f5w6fw6q 1418 9 a a DT cord-006870-f5w6fw6q 1418 10 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 1418 11 facility facility NN cord-006870-f5w6fw6q 1418 12 , , , cord-006870-f5w6fw6q 1418 13 respectively respectively RB cord-006870-f5w6fw6q 1418 14 . . . cord-006870-f5w6fw6q 1419 1 In in IN cord-006870-f5w6fw6q 1419 2 subgroup subgroup NN cord-006870-f5w6fw6q 1419 3 analysis analysis NN cord-006870-f5w6fw6q 1419 4 , , , cord-006870-f5w6fw6q 1419 5 thirty thirty CD cord-006870-f5w6fw6q 1419 6 - - HYPH cord-006870-f5w6fw6q 1419 7 day day NN cord-006870-f5w6fw6q 1419 8 mortality mortality NN cord-006870-f5w6fw6q 1419 9 for for IN cord-006870-f5w6fw6q 1419 10 midbrain midbrain NN cord-006870-f5w6fw6q 1419 11 , , , cord-006870-f5w6fw6q 1419 12 pons pons NNP cord-006870-f5w6fw6q 1419 13 and and CC cord-006870-f5w6fw6q 1419 14 combined combined JJ cord-006870-f5w6fw6q 1419 15 pons pons NNP cord-006870-f5w6fw6q 1419 16 / / SYM cord-006870-f5w6fw6q 1419 17 midbrain midbrain NN cord-006870-f5w6fw6q 1419 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1419 19 was be VBD cord-006870-f5w6fw6q 1419 20 0 0 CD cord-006870-f5w6fw6q 1419 21 % % NN cord-006870-f5w6fw6q 1419 22 , , , cord-006870-f5w6fw6q 1419 23 57 57 CD cord-006870-f5w6fw6q 1419 24 % % NN cord-006870-f5w6fw6q 1419 25 and and CC cord-006870-f5w6fw6q 1419 26 100 100 CD cord-006870-f5w6fw6q 1419 27 % % NN cord-006870-f5w6fw6q 1419 28 , , , cord-006870-f5w6fw6q 1419 29 respectively respectively RB cord-006870-f5w6fw6q 1419 30 . . . cord-006870-f5w6fw6q 1420 1 Spontaneous spontaneous JJ cord-006870-f5w6fw6q 1420 2 brainstem brainstem NN cord-006870-f5w6fw6q 1420 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1420 4 remains remain VBZ cord-006870-f5w6fw6q 1420 5 an an DT cord-006870-f5w6fw6q 1420 6 uncommon uncommon JJ cord-006870-f5w6fw6q 1420 7 but but CC cord-006870-f5w6fw6q 1420 8 highly highly RB cord-006870-f5w6fw6q 1420 9 fatal fatal JJ cord-006870-f5w6fw6q 1420 10 clinical clinical JJ cord-006870-f5w6fw6q 1420 11 entity entity NN cord-006870-f5w6fw6q 1420 12 . . . cord-006870-f5w6fw6q 1421 1 More More JJR cord-006870-f5w6fw6q 1421 2 than than IN cord-006870-f5w6fw6q 1421 3 one one CD cord-006870-f5w6fw6q 1421 4 - - HYPH cord-006870-f5w6fw6q 1421 5 half half NN cord-006870-f5w6fw6q 1421 6 die die NN cord-006870-f5w6fw6q 1421 7 within within IN cord-006870-f5w6fw6q 1421 8 30 30 CD cord-006870-f5w6fw6q 1421 9 days day NNS cord-006870-f5w6fw6q 1421 10 . . . cord-006870-f5w6fw6q 1422 1 Only only RB cord-006870-f5w6fw6q 1422 2 a a DT cord-006870-f5w6fw6q 1422 3 minority minority NN cord-006870-f5w6fw6q 1422 4 are be VBP cord-006870-f5w6fw6q 1422 5 discharged discharge VBN cord-006870-f5w6fw6q 1422 6 to to IN cord-006870-f5w6fw6q 1422 7 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 1422 8 or or CC cord-006870-f5w6fw6q 1422 9 home home NN cord-006870-f5w6fw6q 1422 10 . . . cord-006870-f5w6fw6q 1423 1 In in IN cord-006870-f5w6fw6q 1423 2 sub sub JJ cord-006870-f5w6fw6q 1423 3 - - JJ cord-006870-f5w6fw6q 1423 4 group group JJ cord-006870-f5w6fw6q 1423 5 analysis analysis NN cord-006870-f5w6fw6q 1423 6 , , , cord-006870-f5w6fw6q 1423 7 location location NN cord-006870-f5w6fw6q 1423 8 of of IN cord-006870-f5w6fw6q 1423 9 brainstem brainstem NN cord-006870-f5w6fw6q 1423 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1423 11 was be VBD cord-006870-f5w6fw6q 1423 12 shown show VBN cord-006870-f5w6fw6q 1423 13 to to TO cord-006870-f5w6fw6q 1423 14 influence influence VB cord-006870-f5w6fw6q 1423 15 outcome outcome NN cord-006870-f5w6fw6q 1423 16 , , , cord-006870-f5w6fw6q 1423 17 with with IN cord-006870-f5w6fw6q 1423 18 100 100 CD cord-006870-f5w6fw6q 1423 19 % % NN cord-006870-f5w6fw6q 1423 20 mortality mortality NN cord-006870-f5w6fw6q 1423 21 in in IN cord-006870-f5w6fw6q 1423 22 case case NN cord-006870-f5w6fw6q 1423 23 of of IN cord-006870-f5w6fw6q 1423 24 combined combined JJ cord-006870-f5w6fw6q 1423 25 pons pons NNP cord-006870-f5w6fw6q 1423 26 / / SYM cord-006870-f5w6fw6q 1423 27 midbrain midbrain NN cord-006870-f5w6fw6q 1423 28 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1423 29 , , , cord-006870-f5w6fw6q 1423 30 and and CC cord-006870-f5w6fw6q 1423 31 more more JJR cord-006870-f5w6fw6q 1423 32 than than IN cord-006870-f5w6fw6q 1423 33 50 50 CD cord-006870-f5w6fw6q 1423 34 % % NN cord-006870-f5w6fw6q 1423 35 mortality mortality NN cord-006870-f5w6fw6q 1423 36 with with IN cord-006870-f5w6fw6q 1423 37 pontine pontine JJ cord-006870-f5w6fw6q 1423 38 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1423 39 . . . cord-006870-f5w6fw6q 1424 1 Midbrain Midbrain NNP cord-006870-f5w6fw6q 1424 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1424 3 was be VBD cord-006870-f5w6fw6q 1424 4 associated associate VBN cord-006870-f5w6fw6q 1424 5 with with IN cord-006870-f5w6fw6q 1424 6 good good JJ cord-006870-f5w6fw6q 1424 7 outcome outcome NN cord-006870-f5w6fw6q 1424 8 with with IN cord-006870-f5w6fw6q 1424 9 100 100 CD cord-006870-f5w6fw6q 1424 10 % % NN cord-006870-f5w6fw6q 1424 11 survival survival NN cord-006870-f5w6fw6q 1424 12 . . . cord-006870-f5w6fw6q 1424 13 _SP cord-006870-f5w6fw6q 1425 1 Patients patient NNS cord-006870-f5w6fw6q 1425 2 with with IN cord-006870-f5w6fw6q 1425 3 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1425 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1425 5 ( ( -LRB- cord-006870-f5w6fw6q 1425 6 ICH ICH NNP cord-006870-f5w6fw6q 1425 7 ) ) -RRB- cord-006870-f5w6fw6q 1425 8 frequently frequently RB cord-006870-f5w6fw6q 1425 9 present present JJ cord-006870-f5w6fw6q 1425 10 with with IN cord-006870-f5w6fw6q 1425 11 hypertension hypertension NN cord-006870-f5w6fw6q 1425 12 . . . cord-006870-f5w6fw6q 1426 1 It -PRON- PRP cord-006870-f5w6fw6q 1426 2 is be VBZ cord-006870-f5w6fw6q 1426 3 unclear unclear JJ cord-006870-f5w6fw6q 1426 4 whether whether IN cord-006870-f5w6fw6q 1426 5 this this DT cord-006870-f5w6fw6q 1426 6 is be VBZ cord-006870-f5w6fw6q 1426 7 due due JJ cord-006870-f5w6fw6q 1426 8 to to IN cord-006870-f5w6fw6q 1426 9 preexisting preexisting JJ cord-006870-f5w6fw6q 1426 10 hypertension hypertension NN cord-006870-f5w6fw6q 1426 11 ( ( -LRB- cord-006870-f5w6fw6q 1426 12 prHTN prhtn NN cord-006870-f5w6fw6q 1426 13 ) ) -RRB- cord-006870-f5w6fw6q 1426 14 causing cause VBG cord-006870-f5w6fw6q 1426 15 the the DT cord-006870-f5w6fw6q 1426 16 bleed bleed NN cord-006870-f5w6fw6q 1426 17 , , , cord-006870-f5w6fw6q 1426 18 an an DT cord-006870-f5w6fw6q 1426 19 effect effect NN cord-006870-f5w6fw6q 1426 20 of of IN cord-006870-f5w6fw6q 1426 21 the the DT cord-006870-f5w6fw6q 1426 22 bleed bleed NN cord-006870-f5w6fw6q 1426 23 , , , cord-006870-f5w6fw6q 1426 24 or or CC cord-006870-f5w6fw6q 1426 25 both both DT cord-006870-f5w6fw6q 1426 26 . . . cord-006870-f5w6fw6q 1427 1 We -PRON- PRP cord-006870-f5w6fw6q 1427 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 1427 3 analyzed analyze VBD cord-006870-f5w6fw6q 1427 4 a a DT cord-006870-f5w6fw6q 1427 5 single single JJ cord-006870-f5w6fw6q 1427 6 - - HYPH cord-006870-f5w6fw6q 1427 7 institution institution NN cord-006870-f5w6fw6q 1427 8 cohort cohort NN cord-006870-f5w6fw6q 1427 9 of of IN cord-006870-f5w6fw6q 1427 10 ICH ICH NNP cord-006870-f5w6fw6q 1427 11 patients patient NNS cord-006870-f5w6fw6q 1427 12 presenting present VBG cord-006870-f5w6fw6q 1427 13 between between IN cord-006870-f5w6fw6q 1427 14 2013 2013 CD cord-006870-f5w6fw6q 1427 15 and and CC cord-006870-f5w6fw6q 1427 16 2016 2016 CD cord-006870-f5w6fw6q 1427 17 . . . cord-006870-f5w6fw6q 1428 1 Data datum NNS cord-006870-f5w6fw6q 1428 2 included include VBD cord-006870-f5w6fw6q 1428 3 home home NN cord-006870-f5w6fw6q 1428 4 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1428 5 use use NN cord-006870-f5w6fw6q 1428 6 ; ; , cord-006870-f5w6fw6q 1428 7 aSBP asbp XX cord-006870-f5w6fw6q 1428 8 ; ; : cord-006870-f5w6fw6q 1428 9 TTE TTE NNP cord-006870-f5w6fw6q 1428 10 , , , cord-006870-f5w6fw6q 1428 11 and and CC cord-006870-f5w6fw6q 1428 12 EKG ekg NN cord-006870-f5w6fw6q 1428 13 and and CC cord-006870-f5w6fw6q 1428 14 imaging imaging NN cord-006870-f5w6fw6q 1428 15 results result NNS cord-006870-f5w6fw6q 1428 16 ; ; : cord-006870-f5w6fw6q 1428 17 and and CC cord-006870-f5w6fw6q 1428 18 nicardipine nicardipine NNP cord-006870-f5w6fw6q 1428 19 administration administration NN cord-006870-f5w6fw6q 1428 20 . . . cord-006870-f5w6fw6q 1429 1 The the DT cord-006870-f5w6fw6q 1429 2 primary primary JJ cord-006870-f5w6fw6q 1429 3 objective objective NN cord-006870-f5w6fw6q 1429 4 was be VBD cord-006870-f5w6fw6q 1429 5 to to TO cord-006870-f5w6fw6q 1429 6 assess assess VB cord-006870-f5w6fw6q 1429 7 the the DT cord-006870-f5w6fw6q 1429 8 relationship relationship NN cord-006870-f5w6fw6q 1429 9 between between IN cord-006870-f5w6fw6q 1429 10 prHTN prHTN NNS cord-006870-f5w6fw6q 1429 11 and and CC cord-006870-f5w6fw6q 1429 12 aSBP asbp XX cord-006870-f5w6fw6q 1429 13 , , , cord-006870-f5w6fw6q 1429 14 while while IN cord-006870-f5w6fw6q 1429 15 the the DT cord-006870-f5w6fw6q 1429 16 secondary secondary JJ cord-006870-f5w6fw6q 1429 17 objectives objective NNS cord-006870-f5w6fw6q 1429 18 were be VBD cord-006870-f5w6fw6q 1429 19 to to TO cord-006870-f5w6fw6q 1429 20 assess assess VB cord-006870-f5w6fw6q 1429 21 the the DT cord-006870-f5w6fw6q 1429 22 relationship relationship NN cord-006870-f5w6fw6q 1429 23 between between IN cord-006870-f5w6fw6q 1429 24 prHTN prhtn NN cord-006870-f5w6fw6q 1429 25 , , , cord-006870-f5w6fw6q 1429 26 imaging imaging NN cord-006870-f5w6fw6q 1429 27 and and CC cord-006870-f5w6fw6q 1429 28 acute acute JJ cord-006870-f5w6fw6q 1429 29 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1429 30 requirements requirement NNS cord-006870-f5w6fw6q 1429 31 . . . cord-006870-f5w6fw6q 1430 1 112 112 CD cord-006870-f5w6fw6q 1430 2 ICH ICH NNP cord-006870-f5w6fw6q 1430 3 patients patient NNS cord-006870-f5w6fw6q 1430 4 met meet VBD cord-006870-f5w6fw6q 1430 5 inclusion inclusion NN cord-006870-f5w6fw6q 1430 6 criteria criterion NNS cord-006870-f5w6fw6q 1430 7 . . . cord-006870-f5w6fw6q 1431 1 In in IN cord-006870-f5w6fw6q 1431 2 our -PRON- PRP$ cord-006870-f5w6fw6q 1431 3 assessment assessment NN cord-006870-f5w6fw6q 1431 4 for for IN cord-006870-f5w6fw6q 1431 5 prHTN prHTN NNS cord-006870-f5w6fw6q 1431 6 , , , cord-006870-f5w6fw6q 1431 7 we -PRON- PRP cord-006870-f5w6fw6q 1431 8 found find VBD cord-006870-f5w6fw6q 1431 9 that that IN cord-006870-f5w6fw6q 1431 10 46 46 CD cord-006870-f5w6fw6q 1431 11 % % NN cord-006870-f5w6fw6q 1431 12 of of IN cord-006870-f5w6fw6q 1431 13 patients patient NNS cord-006870-f5w6fw6q 1431 14 were be VBD cord-006870-f5w6fw6q 1431 15 on on IN cord-006870-f5w6fw6q 1431 16 antihypertensives antihypertensives NNP cord-006870-f5w6fw6q 1431 17 , , , cord-006870-f5w6fw6q 1431 18 16 16 CD cord-006870-f5w6fw6q 1431 19 % % NN cord-006870-f5w6fw6q 1431 20 had have VBD cord-006870-f5w6fw6q 1431 21 LVH LVH NNP cord-006870-f5w6fw6q 1431 22 on on IN cord-006870-f5w6fw6q 1431 23 EKG EKG NNP cord-006870-f5w6fw6q 1431 24 , , , cord-006870-f5w6fw6q 1431 25 and and CC cord-006870-f5w6fw6q 1431 26 15 15 CD cord-006870-f5w6fw6q 1431 27 % % NN cord-006870-f5w6fw6q 1431 28 had have VBD cord-006870-f5w6fw6q 1431 29 LVH LVH NNP cord-006870-f5w6fw6q 1431 30 on on IN cord-006870-f5w6fw6q 1431 31 TTE TTE NNP cord-006870-f5w6fw6q 1431 32 . . . cord-006870-f5w6fw6q 1432 1 There there EX cord-006870-f5w6fw6q 1432 2 was be VBD cord-006870-f5w6fw6q 1432 3 a a DT cord-006870-f5w6fw6q 1432 4 significant significant JJ cord-006870-f5w6fw6q 1432 5 relationship relationship NN cord-006870-f5w6fw6q 1432 6 between between IN cord-006870-f5w6fw6q 1432 7 LVH LVH NNP cord-006870-f5w6fw6q 1432 8 on on IN cord-006870-f5w6fw6q 1432 9 TTE TTE NNP cord-006870-f5w6fw6q 1432 10 and and CC cord-006870-f5w6fw6q 1432 11 LVH LVH NNP cord-006870-f5w6fw6q 1432 12 on on IN cord-006870-f5w6fw6q 1432 13 EKG EKG NNP cord-006870-f5w6fw6q 1432 14 ( ( -LRB- cord-006870-f5w6fw6q 1432 15 p<0.001 p<0.001 JJ cord-006870-f5w6fw6q 1432 16 ) ) -RRB- cord-006870-f5w6fw6q 1432 17 , , , cord-006870-f5w6fw6q 1432 18 but but CC cord-006870-f5w6fw6q 1432 19 not not RB cord-006870-f5w6fw6q 1432 20 between between IN cord-006870-f5w6fw6q 1432 21 home home NN cord-006870-f5w6fw6q 1432 22 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1432 23 use use NN cord-006870-f5w6fw6q 1432 24 and and CC cord-006870-f5w6fw6q 1432 25 presence presence NN cord-006870-f5w6fw6q 1432 26 of of IN cord-006870-f5w6fw6q 1432 27 LVH LVH NNP cord-006870-f5w6fw6q 1432 28 using use VBG cord-006870-f5w6fw6q 1432 29 either either DT cord-006870-f5w6fw6q 1432 30 modality modality NN cord-006870-f5w6fw6q 1432 31 . . . cord-006870-f5w6fw6q 1433 1 aSBP aSBP NNP cord-006870-f5w6fw6q 1433 2 was be VBD cord-006870-f5w6fw6q 1433 3 higher high JJR cord-006870-f5w6fw6q 1433 4 for for IN cord-006870-f5w6fw6q 1433 5 all all DT cord-006870-f5w6fw6q 1433 6 patients patient NNS cord-006870-f5w6fw6q 1433 7 with with IN cord-006870-f5w6fw6q 1433 8 markers marker NNS cord-006870-f5w6fw6q 1433 9 of of IN cord-006870-f5w6fw6q 1433 10 pHTN phtn NN cord-006870-f5w6fw6q 1433 11 , , , cord-006870-f5w6fw6q 1433 12 but but CC cord-006870-f5w6fw6q 1433 13 this this DT cord-006870-f5w6fw6q 1433 14 was be VBD cord-006870-f5w6fw6q 1433 15 only only RB cord-006870-f5w6fw6q 1433 16 significant significant JJ cord-006870-f5w6fw6q 1433 17 for for IN cord-006870-f5w6fw6q 1433 18 patients patient NNS cord-006870-f5w6fw6q 1433 19 with with IN cord-006870-f5w6fw6q 1433 20 LVH LVH NNP cord-006870-f5w6fw6q 1433 21 on on IN cord-006870-f5w6fw6q 1433 22 TTE TTE NNP cord-006870-f5w6fw6q 1433 23 ( ( -LRB- cord-006870-f5w6fw6q 1433 24 181mmHg 181mmHg NNS cord-006870-f5w6fw6q 1433 25 , , , cord-006870-f5w6fw6q 1433 26 IQR IQR NNP cord-006870-f5w6fw6q 1433 27 153 153 CD cord-006870-f5w6fw6q 1433 28 - - SYM cord-006870-f5w6fw6q 1433 29 214 214 CD cord-006870-f5w6fw6q 1433 30 vs. vs. FW cord-006870-f5w6fw6q 1433 31 152mmHg 152mmHg NNS cord-006870-f5w6fw6q 1433 32 , , , cord-006870-f5w6fw6q 1433 33 IQR IQR NNP cord-006870-f5w6fw6q 1433 34 137 137 CD cord-006870-f5w6fw6q 1433 35 - - SYM cord-006870-f5w6fw6q 1433 36 169 169 CD cord-006870-f5w6fw6q 1433 37 , , , cord-006870-f5w6fw6q 1433 38 p p NN cord-006870-f5w6fw6q 1433 39 < < XX cord-006870-f5w6fw6q 1433 40 0.001 0.001 CD cord-006870-f5w6fw6q 1433 41 ) ) -RRB- cord-006870-f5w6fw6q 1433 42 and and CC cord-006870-f5w6fw6q 1433 43 patients patient NNS cord-006870-f5w6fw6q 1433 44 with with IN cord-006870-f5w6fw6q 1433 45 LVH LVH NNP cord-006870-f5w6fw6q 1433 46 on on IN cord-006870-f5w6fw6q 1433 47 EKG EKG NNP cord-006870-f5w6fw6q 1433 48 ( ( -LRB- cord-006870-f5w6fw6q 1433 49 195 195 CD cord-006870-f5w6fw6q 1433 50 mm mm NN cord-006870-f5w6fw6q 1434 1 Hg Hg NNP cord-006870-f5w6fw6q 1434 2 , , , cord-006870-f5w6fw6q 1434 3 IQR IQR NNP cord-006870-f5w6fw6q 1434 4 155 155 CD cord-006870-f5w6fw6q 1434 5 - - SYM cord-006870-f5w6fw6q 1434 6 216 216 CD cord-006870-f5w6fw6q 1434 7 vs. vs. NN cord-006870-f5w6fw6q 1434 8 147 147 CD cord-006870-f5w6fw6q 1434 9 mm mm NN cord-006870-f5w6fw6q 1435 1 Hg Hg NNP cord-006870-f5w6fw6q 1435 2 , , , cord-006870-f5w6fw6q 1435 3 IQR IQR NNP cord-006870-f5w6fw6q 1435 4 129 129 CD cord-006870-f5w6fw6q 1435 5 - - SYM cord-006870-f5w6fw6q 1435 6 163 163 CD cord-006870-f5w6fw6q 1435 7 , , , cord-006870-f5w6fw6q 1435 8 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1435 9 ) ) -RRB- cord-006870-f5w6fw6q 1435 10 . . . cord-006870-f5w6fw6q 1436 1 All all DT cord-006870-f5w6fw6q 1436 2 patients patient NNS cord-006870-f5w6fw6q 1436 3 with with IN cord-006870-f5w6fw6q 1436 4 markers marker NNS cord-006870-f5w6fw6q 1436 5 of of IN cord-006870-f5w6fw6q 1436 6 prHTN prHTN NNS cord-006870-f5w6fw6q 1436 7 were be VBD cord-006870-f5w6fw6q 1436 8 more more RBR cord-006870-f5w6fw6q 1436 9 likely likely JJ cord-006870-f5w6fw6q 1436 10 to to TO cord-006870-f5w6fw6q 1436 11 require require VB cord-006870-f5w6fw6q 1436 12 nicardipine nicardipine JJ cord-006870-f5w6fw6q 1436 13 , , , cord-006870-f5w6fw6q 1436 14 but but CC cord-006870-f5w6fw6q 1436 15 this this DT cord-006870-f5w6fw6q 1436 16 was be VBD cord-006870-f5w6fw6q 1436 17 only only RB cord-006870-f5w6fw6q 1436 18 significant significant JJ cord-006870-f5w6fw6q 1436 19 for for IN cord-006870-f5w6fw6q 1436 20 patients patient NNS cord-006870-f5w6fw6q 1436 21 with with IN cord-006870-f5w6fw6q 1436 22 LVH LVH NNP cord-006870-f5w6fw6q 1436 23 on on IN cord-006870-f5w6fw6q 1436 24 TTE TTE NNP cord-006870-f5w6fw6q 1436 25 ( ( -LRB- cord-006870-f5w6fw6q 1436 26 94 94 CD cord-006870-f5w6fw6q 1436 27 % % NN cord-006870-f5w6fw6q 1436 28 vs. vs. CC cord-006870-f5w6fw6q 1436 29 64 64 CD cord-006870-f5w6fw6q 1436 30 % % NN cord-006870-f5w6fw6q 1436 31 , , , cord-006870-f5w6fw6q 1436 32 p=0.016 p=0.016 JJS cord-006870-f5w6fw6q 1436 33 ) ) -RRB- cord-006870-f5w6fw6q 1436 34 and and CC cord-006870-f5w6fw6q 1436 35 patients patient NNS cord-006870-f5w6fw6q 1436 36 with with IN cord-006870-f5w6fw6q 1436 37 LVH LVH NNP cord-006870-f5w6fw6q 1436 38 on on IN cord-006870-f5w6fw6q 1436 39 EKG EKG NNP cord-006870-f5w6fw6q 1436 40 ( ( -LRB- cord-006870-f5w6fw6q 1436 41 83 83 CD cord-006870-f5w6fw6q 1436 42 % % NN cord-006870-f5w6fw6q 1436 43 vs. vs. IN cord-006870-f5w6fw6q 1436 44 52 52 CD cord-006870-f5w6fw6q 1436 45 % % NN cord-006870-f5w6fw6q 1436 46 , , , cord-006870-f5w6fw6q 1436 47 p=0.018 p=0.018 NNP cord-006870-f5w6fw6q 1436 48 ) ) -RRB- cord-006870-f5w6fw6q 1436 49 . . . cord-006870-f5w6fw6q 1437 1 All all DT cord-006870-f5w6fw6q 1437 2 patients patient NNS cord-006870-f5w6fw6q 1437 3 with with IN cord-006870-f5w6fw6q 1437 4 markers marker NNS cord-006870-f5w6fw6q 1437 5 of of IN cord-006870-f5w6fw6q 1437 6 prHTN prHTN NNS cord-006870-f5w6fw6q 1437 7 were be VBD cord-006870-f5w6fw6q 1437 8 more more RBR cord-006870-f5w6fw6q 1437 9 likely likely JJ cord-006870-f5w6fw6q 1437 10 to to TO cord-006870-f5w6fw6q 1437 11 have have VB cord-006870-f5w6fw6q 1437 12 deep deep JJ cord-006870-f5w6fw6q 1437 13 bleeds bleed NNS cord-006870-f5w6fw6q 1437 14 ( ( -LRB- cord-006870-f5w6fw6q 1437 15 p=0.017 p=0.017 NNS cord-006870-f5w6fw6q 1438 1 for for IN cord-006870-f5w6fw6q 1438 2 patients patient NNS cord-006870-f5w6fw6q 1438 3 with with IN cord-006870-f5w6fw6q 1438 4 LVH LVH NNP cord-006870-f5w6fw6q 1438 5 on on IN cord-006870-f5w6fw6q 1438 6 EKG EKG NNP cord-006870-f5w6fw6q 1438 7 vs. vs. FW cord-006870-f5w6fw6q 1438 8 those those DT cord-006870-f5w6fw6q 1438 9 without without IN cord-006870-f5w6fw6q 1438 10 LVH LVH NNP cord-006870-f5w6fw6q 1438 11 on on IN cord-006870-f5w6fw6q 1438 12 EKG EKG NNP cord-006870-f5w6fw6q 1438 13 ) ) -RRB- cord-006870-f5w6fw6q 1438 14 . . . cord-006870-f5w6fw6q 1439 1 There there EX cord-006870-f5w6fw6q 1439 2 was be VBD cord-006870-f5w6fw6q 1439 3 no no DT cord-006870-f5w6fw6q 1439 4 relationship relationship NN cord-006870-f5w6fw6q 1439 5 between between IN cord-006870-f5w6fw6q 1439 6 any any DT cord-006870-f5w6fw6q 1439 7 markers marker NNS cord-006870-f5w6fw6q 1439 8 of of IN cord-006870-f5w6fw6q 1439 9 prHTN prHTN NNS cord-006870-f5w6fw6q 1439 10 and and CC cord-006870-f5w6fw6q 1439 11 the the DT cord-006870-f5w6fw6q 1439 12 presence presence NN cord-006870-f5w6fw6q 1439 13 of of IN cord-006870-f5w6fw6q 1439 14 a a DT cord-006870-f5w6fw6q 1439 15 spot spot NN cord-006870-f5w6fw6q 1439 16 sign sign NN cord-006870-f5w6fw6q 1439 17 . . . cord-006870-f5w6fw6q 1440 1 In in IN cord-006870-f5w6fw6q 1440 2 patients patient NNS cord-006870-f5w6fw6q 1440 3 with with IN cord-006870-f5w6fw6q 1440 4 ICH ICH NNP cord-006870-f5w6fw6q 1440 5 , , , cord-006870-f5w6fw6q 1440 6 prHTN prHTN NNP cord-006870-f5w6fw6q 1440 7 is be VBZ cord-006870-f5w6fw6q 1440 8 related relate VBN cord-006870-f5w6fw6q 1440 9 to to IN cord-006870-f5w6fw6q 1440 10 higher high JJR cord-006870-f5w6fw6q 1440 11 aSBP asbp XX cord-006870-f5w6fw6q 1440 12 , , , cord-006870-f5w6fw6q 1440 13 deep deep JJ cord-006870-f5w6fw6q 1440 14 bleed bleed NN cord-006870-f5w6fw6q 1440 15 location location NN cord-006870-f5w6fw6q 1440 16 , , , cord-006870-f5w6fw6q 1440 17 and and CC cord-006870-f5w6fw6q 1440 18 increased increase VBD cord-006870-f5w6fw6q 1440 19 acute acute JJ cord-006870-f5w6fw6q 1440 20 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1440 21 requirements requirement NNS cord-006870-f5w6fw6q 1440 22 . . . cord-006870-f5w6fw6q 1441 1 All all DT cord-006870-f5w6fw6q 1441 2 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1441 3 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1441 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1441 5 ( ( -LRB- cord-006870-f5w6fw6q 1441 6 sICH sich NN cord-006870-f5w6fw6q 1441 7 ) ) -RRB- cord-006870-f5w6fw6q 1441 8 patients patient NNS cord-006870-f5w6fw6q 1441 9 , , , cord-006870-f5w6fw6q 1441 10 including include VBG cord-006870-f5w6fw6q 1441 11 those those DT cord-006870-f5w6fw6q 1441 12 with with IN cord-006870-f5w6fw6q 1441 13 low low JJ cord-006870-f5w6fw6q 1441 14 severity severity NN cord-006870-f5w6fw6q 1441 15 are be VBP cord-006870-f5w6fw6q 1441 16 uniformly uniformly RB cord-006870-f5w6fw6q 1441 17 admitted admit VBN cord-006870-f5w6fw6q 1441 18 to to IN cord-006870-f5w6fw6q 1441 19 the the DT cord-006870-f5w6fw6q 1441 20 intensive intensive JJ cord-006870-f5w6fw6q 1441 21 care care NN cord-006870-f5w6fw6q 1441 22 unit unit NN cord-006870-f5w6fw6q 1441 23 ( ( -LRB- cord-006870-f5w6fw6q 1441 24 ICU ICU NNP cord-006870-f5w6fw6q 1441 25 ) ) -RRB- cord-006870-f5w6fw6q 1441 26 at at IN cord-006870-f5w6fw6q 1441 27 our -PRON- PRP$ cord-006870-f5w6fw6q 1441 28 institution institution NN cord-006870-f5w6fw6q 1441 29 . . . cord-006870-f5w6fw6q 1442 1 Many many JJ cord-006870-f5w6fw6q 1442 2 may may MD cord-006870-f5w6fw6q 1442 3 not not RB cord-006870-f5w6fw6q 1442 4 benefit benefit VB cord-006870-f5w6fw6q 1442 5 from from IN cord-006870-f5w6fw6q 1442 6 this this DT cord-006870-f5w6fw6q 1442 7 high high JJ cord-006870-f5w6fw6q 1442 8 - - HYPH cord-006870-f5w6fw6q 1442 9 intensity intensity NN cord-006870-f5w6fw6q 1442 10 observation observation NN cord-006870-f5w6fw6q 1442 11 and and CC cord-006870-f5w6fw6q 1442 12 leave leave VB cord-006870-f5w6fw6q 1442 13 the the DT cord-006870-f5w6fw6q 1442 14 ICU ICU NNP cord-006870-f5w6fw6q 1442 15 within within IN cord-006870-f5w6fw6q 1442 16 24 24 CD cord-006870-f5w6fw6q 1442 17 hours hour NNS cord-006870-f5w6fw6q 1442 18 without without IN cord-006870-f5w6fw6q 1442 19 experiencing experience VBG cord-006870-f5w6fw6q 1442 20 any any DT cord-006870-f5w6fw6q 1442 21 complications complication NNS cord-006870-f5w6fw6q 1442 22 . . . cord-006870-f5w6fw6q 1443 1 Identifying identify VBG cord-006870-f5w6fw6q 1443 2 low low JJ cord-006870-f5w6fw6q 1443 3 - - HYPH cord-006870-f5w6fw6q 1443 4 risk risk NN cord-006870-f5w6fw6q 1443 5 characteristics characteristic NNS cord-006870-f5w6fw6q 1443 6 could could MD cord-006870-f5w6fw6q 1443 7 aid aid VB cord-006870-f5w6fw6q 1443 8 in in IN cord-006870-f5w6fw6q 1443 9 triaging triage VBG cord-006870-f5w6fw6q 1443 10 such such JJ cord-006870-f5w6fw6q 1443 11 patients patient NNS cord-006870-f5w6fw6q 1443 12 to to TO cord-006870-f5w6fw6q 1443 13 stroke stroke VB cord-006870-f5w6fw6q 1443 14 units unit NNS cord-006870-f5w6fw6q 1443 15 instead instead RB cord-006870-f5w6fw6q 1443 16 . . . cord-006870-f5w6fw6q 1444 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 1444 2 data datum NNS cord-006870-f5w6fw6q 1444 3 collection collection NN cord-006870-f5w6fw6q 1444 4 of of IN cord-006870-f5w6fw6q 1444 5 all all DT cord-006870-f5w6fw6q 1444 6 sICH sich NN cord-006870-f5w6fw6q 1444 7 patients patient NNS cord-006870-f5w6fw6q 1444 8 admitted admit VBN cord-006870-f5w6fw6q 1444 9 to to IN cord-006870-f5w6fw6q 1444 10 our -PRON- PRP$ cord-006870-f5w6fw6q 1444 11 institution institution NN cord-006870-f5w6fw6q 1444 12 from from IN cord-006870-f5w6fw6q 1444 13 June June NNP cord-006870-f5w6fw6q 1444 14 1 1 CD cord-006870-f5w6fw6q 1444 15 , , , cord-006870-f5w6fw6q 1444 16 2013-June 2013-june CD cord-006870-f5w6fw6q 1444 17 30 30 CD cord-006870-f5w6fw6q 1444 18 , , , cord-006870-f5w6fw6q 1444 19 2016 2016 CD cord-006870-f5w6fw6q 1444 20 included include VBN cord-006870-f5w6fw6q 1444 21 ICH ICH NNP cord-006870-f5w6fw6q 1444 22 score score VB cord-006870-f5w6fw6q 1444 23 , , , cord-006870-f5w6fw6q 1444 24 need need VB cord-006870-f5w6fw6q 1444 25 for for IN cord-006870-f5w6fw6q 1444 26 surgical surgical JJ cord-006870-f5w6fw6q 1444 27 interventions intervention NNS cord-006870-f5w6fw6q 1444 28 , , , cord-006870-f5w6fw6q 1444 29 medical medical JJ cord-006870-f5w6fw6q 1444 30 complications complication NNS cord-006870-f5w6fw6q 1444 31 , , , cord-006870-f5w6fw6q 1444 32 and and CC cord-006870-f5w6fw6q 1444 33 ICU ICU NNP cord-006870-f5w6fw6q 1444 34 / / SYM cord-006870-f5w6fw6q 1444 35 hospital hospital NN cord-006870-f5w6fw6q 1444 36 LOS LOS NNP cord-006870-f5w6fw6q 1444 37 . . . cord-006870-f5w6fw6q 1445 1 We -PRON- PRP cord-006870-f5w6fw6q 1445 2 analyzed analyze VBD cord-006870-f5w6fw6q 1445 3 variables variable NNS cord-006870-f5w6fw6q 1445 4 predicting predict VBG cord-006870-f5w6fw6q 1445 5 short short JJ cord-006870-f5w6fw6q 1445 6 ( ( -LRB- cord-006870-f5w6fw6q 1445 7 < < XX cord-006870-f5w6fw6q 1445 8 24 24 CD cord-006870-f5w6fw6q 1445 9 hour hour NN cord-006870-f5w6fw6q 1445 10 ) ) -RRB- cord-006870-f5w6fw6q 1446 1 ICU ICU NNP cord-006870-f5w6fw6q 1446 2 LOS LOS NNP cord-006870-f5w6fw6q 1446 3 among among IN cord-006870-f5w6fw6q 1446 4 low low JJ cord-006870-f5w6fw6q 1446 5 severity severity NN cord-006870-f5w6fw6q 1447 1 ( ( -LRB- cord-006870-f5w6fw6q 1447 2 LS ls NN cord-006870-f5w6fw6q 1447 3 - - HYPH cord-006870-f5w6fw6q 1447 4 ICH ICH NNP cord-006870-f5w6fw6q 1447 5 ) ) -RRB- cord-006870-f5w6fw6q 1447 6 patients patient NNS cord-006870-f5w6fw6q 1447 7 ( ( -LRB- cord-006870-f5w6fw6q 1447 8 defined define VBN cord-006870-f5w6fw6q 1447 9 as as IN cord-006870-f5w6fw6q 1447 10 those those DT cord-006870-f5w6fw6q 1447 11 with with IN cord-006870-f5w6fw6q 1447 12 ICH ICH NNP cord-006870-f5w6fw6q 1447 13 score score NN cord-006870-f5w6fw6q 1447 14 0 0 CD cord-006870-f5w6fw6q 1447 15 - - SYM cord-006870-f5w6fw6q 1447 16 1 1 CD cord-006870-f5w6fw6q 1447 17 ) ) -RRB- cord-006870-f5w6fw6q 1447 18 . . . cord-006870-f5w6fw6q 1448 1 163 163 CD cord-006870-f5w6fw6q 1448 2 ( ( -LRB- cord-006870-f5w6fw6q 1448 3 52 52 CD cord-006870-f5w6fw6q 1448 4 % % NN cord-006870-f5w6fw6q 1448 5 ) ) -RRB- cord-006870-f5w6fw6q 1448 6 of of IN cord-006870-f5w6fw6q 1448 7 313 313 CD cord-006870-f5w6fw6q 1448 8 sICH sich NN cord-006870-f5w6fw6q 1448 9 patients patient NNS cord-006870-f5w6fw6q 1448 10 had have VBD cord-006870-f5w6fw6q 1448 11 ICH ICH NNP cord-006870-f5w6fw6q 1448 12 scores score NNS cord-006870-f5w6fw6q 1448 13 of of IN cord-006870-f5w6fw6q 1448 14 0 0 CD cord-006870-f5w6fw6q 1448 15 - - SYM cord-006870-f5w6fw6q 1448 16 1 1 CD cord-006870-f5w6fw6q 1448 17 , , , cord-006870-f5w6fw6q 1448 18 of of IN cord-006870-f5w6fw6q 1448 19 which which WDT cord-006870-f5w6fw6q 1448 20 just just RB cord-006870-f5w6fw6q 1448 21 under under IN cord-006870-f5w6fw6q 1448 22 half half PDT cord-006870-f5w6fw6q 1448 23 ( ( -LRB- cord-006870-f5w6fw6q 1448 24 78 78 CD cord-006870-f5w6fw6q 1448 25 ) ) -RRB- cord-006870-f5w6fw6q 1448 26 had have VBD cord-006870-f5w6fw6q 1448 27 ICU ICU NNP cord-006870-f5w6fw6q 1448 28 LOS LOS NNP cord-006870-f5w6fw6q 1448 29 24 24 CD cord-006870-f5w6fw6q 1448 30 hr hr NN cord-006870-f5w6fw6q 1448 31 . . . cord-006870-f5w6fw6q 1449 1 They -PRON- PRP cord-006870-f5w6fw6q 1449 2 also also RB cord-006870-f5w6fw6q 1449 3 spent spend VBD cord-006870-f5w6fw6q 1449 4 significantly significantly RB cord-006870-f5w6fw6q 1449 5 fewer few JJR cord-006870-f5w6fw6q 1449 6 days day NNS cord-006870-f5w6fw6q 1449 7 in in IN cord-006870-f5w6fw6q 1449 8 hospital hospital NN cord-006870-f5w6fw6q 1449 9 ( ( -LRB- cord-006870-f5w6fw6q 1449 10 4 4 CD cord-006870-f5w6fw6q 1449 11 vs vs IN cord-006870-f5w6fw6q 1449 12 9.7 9.7 CD cord-006870-f5w6fw6q 1449 13 , , , cord-006870-f5w6fw6q 1449 14 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1449 15 ) ) -RRB- cord-006870-f5w6fw6q 1449 16 . . . cord-006870-f5w6fw6q 1450 1 We -PRON- PRP cord-006870-f5w6fw6q 1450 2 could could MD cord-006870-f5w6fw6q 1450 3 not not RB cord-006870-f5w6fw6q 1450 4 identify identify VB cord-006870-f5w6fw6q 1450 5 a a DT cord-006870-f5w6fw6q 1450 6 clear clear JJ cord-006870-f5w6fw6q 1450 7 ICH ICH NNP cord-006870-f5w6fw6q 1450 8 score score NN cord-006870-f5w6fw6q 1450 9 cutoff cutoff NN cord-006870-f5w6fw6q 1450 10 that that WDT cord-006870-f5w6fw6q 1450 11 was be VBD cord-006870-f5w6fw6q 1450 12 sensitive sensitive JJ cord-006870-f5w6fw6q 1450 13 enough enough RB cord-006870-f5w6fw6q 1450 14 to to TO cord-006870-f5w6fw6q 1450 15 predict predict VB cord-006870-f5w6fw6q 1450 16 short short JJ cord-006870-f5w6fw6q 1450 17 ICU ICU NNP cord-006870-f5w6fw6q 1450 18 LOS LOS NNP cord-006870-f5w6fw6q 1450 19 . . . cord-006870-f5w6fw6q 1451 1 However however RB cord-006870-f5w6fw6q 1451 2 , , , cord-006870-f5w6fw6q 1451 3 requirement requirement NN cord-006870-f5w6fw6q 1451 4 for for IN cord-006870-f5w6fw6q 1451 5 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1451 6 infusion infusion NN cord-006870-f5w6fw6q 1451 7 and and CC cord-006870-f5w6fw6q 1451 8 early early JJ cord-006870-f5w6fw6q 1451 9 clinical clinical JJ cord-006870-f5w6fw6q 1451 10 deterioration deterioration NN cord-006870-f5w6fw6q 1451 11 correlated correlate VBD cord-006870-f5w6fw6q 1451 12 strongly strongly RB cord-006870-f5w6fw6q 1451 13 with with IN cord-006870-f5w6fw6q 1451 14 longer long JJR cord-006870-f5w6fw6q 1451 15 ICU ICU NNP cord-006870-f5w6fw6q 1451 16 LOS LOS NNP cord-006870-f5w6fw6q 1451 17 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1451 18 . . . cord-006870-f5w6fw6q 1452 1 There there EX cord-006870-f5w6fw6q 1452 2 appears appear VBZ cord-006870-f5w6fw6q 1452 3 to to TO cord-006870-f5w6fw6q 1452 4 be be VB cord-006870-f5w6fw6q 1452 5 a a DT cord-006870-f5w6fw6q 1452 6 subset subset NN cord-006870-f5w6fw6q 1452 7 of of IN cord-006870-f5w6fw6q 1452 8 mild mild JJ cord-006870-f5w6fw6q 1452 9 ICH ICH NNP cord-006870-f5w6fw6q 1452 10 patients patient NNS cord-006870-f5w6fw6q 1452 11 ( ( -LRB- cord-006870-f5w6fw6q 1452 12 ICH ICH NNP cord-006870-f5w6fw6q 1452 13 score score VB cord-006870-f5w6fw6q 1452 14 0 0 CD cord-006870-f5w6fw6q 1452 15 - - SYM cord-006870-f5w6fw6q 1452 16 1 1 CD cord-006870-f5w6fw6q 1452 17 ) ) -RRB- cord-006870-f5w6fw6q 1452 18 who who WP cord-006870-f5w6fw6q 1452 19 do do VBP cord-006870-f5w6fw6q 1452 20 not not RB cord-006870-f5w6fw6q 1452 21 require require VB cord-006870-f5w6fw6q 1452 22 ICU ICU NNP cord-006870-f5w6fw6q 1452 23 observation observation NN cord-006870-f5w6fw6q 1452 24 . . . cord-006870-f5w6fw6q 1453 1 A a DT cord-006870-f5w6fw6q 1453 2 risk risk NN cord-006870-f5w6fw6q 1453 3 assessment assessment NN cord-006870-f5w6fw6q 1453 4 score score NN cord-006870-f5w6fw6q 1453 5 incorporating incorporate VBG cord-006870-f5w6fw6q 1453 6 GCS GCS NNP cord-006870-f5w6fw6q 1453 7 and and CC cord-006870-f5w6fw6q 1453 8 ICH ICH NNP cord-006870-f5w6fw6q 1453 9 volume volume NN cord-006870-f5w6fw6q 1453 10 may may MD cord-006870-f5w6fw6q 1453 11 be be VB cord-006870-f5w6fw6q 1453 12 able able JJ cord-006870-f5w6fw6q 1453 13 to to TO cord-006870-f5w6fw6q 1453 14 delineate delineate VB cord-006870-f5w6fw6q 1453 15 this this DT cord-006870-f5w6fw6q 1453 16 low low JJ cord-006870-f5w6fw6q 1453 17 - - HYPH cord-006870-f5w6fw6q 1453 18 risk risk NN cord-006870-f5w6fw6q 1453 19 population population NN cord-006870-f5w6fw6q 1453 20 who who WP cord-006870-f5w6fw6q 1453 21 could could MD cord-006870-f5w6fw6q 1453 22 instead instead RB cord-006870-f5w6fw6q 1453 23 be be VB cord-006870-f5w6fw6q 1453 24 admitted admit VBN cord-006870-f5w6fw6q 1453 25 to to IN cord-006870-f5w6fw6q 1453 26 a a DT cord-006870-f5w6fw6q 1453 27 stroke stroke NN cord-006870-f5w6fw6q 1453 28 unit unit NN cord-006870-f5w6fw6q 1453 29 , , , cord-006870-f5w6fw6q 1453 30 with with IN cord-006870-f5w6fw6q 1453 31 the the DT cord-006870-f5w6fw6q 1453 32 potential potential NN cord-006870-f5w6fw6q 1453 33 for for IN cord-006870-f5w6fw6q 1453 34 significant significant JJ cord-006870-f5w6fw6q 1453 35 cost cost NN cord-006870-f5w6fw6q 1453 36 saving saving NN cord-006870-f5w6fw6q 1453 37 and and CC cord-006870-f5w6fw6q 1453 38 hospital hospital NN cord-006870-f5w6fw6q 1453 39 efficiency efficiency NN cord-006870-f5w6fw6q 1453 40 . . . cord-006870-f5w6fw6q 1454 1 Obesity obesity NN cord-006870-f5w6fw6q 1454 2 has have VBZ cord-006870-f5w6fw6q 1454 3 been be VBN cord-006870-f5w6fw6q 1454 4 linked link VBN cord-006870-f5w6fw6q 1454 5 with with IN cord-006870-f5w6fw6q 1454 6 relative relative JJ cord-006870-f5w6fw6q 1454 7 longevity longevity NN cord-006870-f5w6fw6q 1454 8 in in IN cord-006870-f5w6fw6q 1454 9 several several JJ cord-006870-f5w6fw6q 1454 10 disease disease NN cord-006870-f5w6fw6q 1454 11 conditions condition NNS cord-006870-f5w6fw6q 1454 12 . . . cord-006870-f5w6fw6q 1455 1 This this DT cord-006870-f5w6fw6q 1455 2 relationship relationship NN cord-006870-f5w6fw6q 1455 3 has have VBZ cord-006870-f5w6fw6q 1455 4 been be VBN cord-006870-f5w6fw6q 1455 5 termed term VBN cord-006870-f5w6fw6q 1455 6 the the DT cord-006870-f5w6fw6q 1455 7 " " `` cord-006870-f5w6fw6q 1455 8 obesity obesity NN cord-006870-f5w6fw6q 1455 9 paradox paradox NN cord-006870-f5w6fw6q 1455 10 . . . cord-006870-f5w6fw6q 1456 1 " " `` cord-006870-f5w6fw6q 1456 2 In in IN cord-006870-f5w6fw6q 1456 3 this this DT cord-006870-f5w6fw6q 1456 4 study study NN cord-006870-f5w6fw6q 1456 5 we -PRON- PRP cord-006870-f5w6fw6q 1456 6 sought seek VBD cord-006870-f5w6fw6q 1456 7 to to TO cord-006870-f5w6fw6q 1456 8 evaluate evaluate VB cord-006870-f5w6fw6q 1456 9 the the DT cord-006870-f5w6fw6q 1456 10 impact impact NN cord-006870-f5w6fw6q 1456 11 of of IN cord-006870-f5w6fw6q 1456 12 obesity obesity NN cord-006870-f5w6fw6q 1456 13 on on IN cord-006870-f5w6fw6q 1456 14 short short JJ cord-006870-f5w6fw6q 1456 15 - - HYPH cord-006870-f5w6fw6q 1456 16 term term NN cord-006870-f5w6fw6q 1456 17 outcomes outcome NNS cord-006870-f5w6fw6q 1456 18 in in IN cord-006870-f5w6fw6q 1456 19 patients patient NNS cord-006870-f5w6fw6q 1456 20 with with IN cord-006870-f5w6fw6q 1456 21 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1456 22 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1456 23 ( ( -LRB- cord-006870-f5w6fw6q 1456 24 ICH ICH NNP cord-006870-f5w6fw6q 1456 25 ) ) -RRB- cord-006870-f5w6fw6q 1456 26 . . . cord-006870-f5w6fw6q 1457 1 Patients patient NNS cord-006870-f5w6fw6q 1457 2 admitted admit VBN cord-006870-f5w6fw6q 1457 3 with with IN cord-006870-f5w6fw6q 1457 4 a a DT cord-006870-f5w6fw6q 1457 5 diagnosis diagnosis NN cord-006870-f5w6fw6q 1457 6 of of IN cord-006870-f5w6fw6q 1457 7 ICH ICH NNP cord-006870-f5w6fw6q 1457 8 were be VBD cord-006870-f5w6fw6q 1457 9 selected select VBN cord-006870-f5w6fw6q 1457 10 from from IN cord-006870-f5w6fw6q 1457 11 the the DT cord-006870-f5w6fw6q 1457 12 2003 2003 CD cord-006870-f5w6fw6q 1457 13 - - SYM cord-006870-f5w6fw6q 1457 14 2014 2014 CD cord-006870-f5w6fw6q 1457 15 Nationwide Nationwide NNP cord-006870-f5w6fw6q 1457 16 Inpatient Inpatient NNP cord-006870-f5w6fw6q 1457 17 Sample Sample NNP cord-006870-f5w6fw6q 1457 18 ( ( -LRB- cord-006870-f5w6fw6q 1457 19 NIS NIS NNP cord-006870-f5w6fw6q 1457 20 ) ) -RRB- cord-006870-f5w6fw6q 1457 21 database database NN cord-006870-f5w6fw6q 1457 22 , , , cord-006870-f5w6fw6q 1457 23 using use VBG cord-006870-f5w6fw6q 1457 24 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 1457 25 codes code NNS cord-006870-f5w6fw6q 1457 26 . . . cord-006870-f5w6fw6q 1458 1 Patients patient NNS cord-006870-f5w6fw6q 1458 2 with with IN cord-006870-f5w6fw6q 1458 3 ICH ICH NNP cord-006870-f5w6fw6q 1458 4 were be VBD cord-006870-f5w6fw6q 1458 5 dichotomized dichotomize VBN cord-006870-f5w6fw6q 1458 6 based base VBN cord-006870-f5w6fw6q 1458 7 on on IN cord-006870-f5w6fw6q 1458 8 the the DT cord-006870-f5w6fw6q 1458 9 presence presence NN cord-006870-f5w6fw6q 1458 10 of of IN cord-006870-f5w6fw6q 1458 11 obesity obesity NN cord-006870-f5w6fw6q 1458 12 as as IN cord-006870-f5w6fw6q 1458 13 a a DT cord-006870-f5w6fw6q 1458 14 coexisting coexist VBG cord-006870-f5w6fw6q 1458 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 1458 16 based base VBN cord-006870-f5w6fw6q 1458 17 on on IN cord-006870-f5w6fw6q 1458 18 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 1458 19 codes code NNS cord-006870-f5w6fw6q 1458 20 and and CC cord-006870-f5w6fw6q 1458 21 diagnosis diagnosis NN cord-006870-f5w6fw6q 1458 22 related relate VBN cord-006870-f5w6fw6q 1458 23 groups group NNS cord-006870-f5w6fw6q 1458 24 . . . cord-006870-f5w6fw6q 1459 1 The the DT cord-006870-f5w6fw6q 1459 2 primary primary JJ cord-006870-f5w6fw6q 1459 3 outcome outcome NN cord-006870-f5w6fw6q 1459 4 measure measure NN cord-006870-f5w6fw6q 1459 5 was be VBD cord-006870-f5w6fw6q 1459 6 in in IN cord-006870-f5w6fw6q 1459 7 - - HYPH cord-006870-f5w6fw6q 1459 8 hospital hospital NN cord-006870-f5w6fw6q 1459 9 mortality mortality NN cord-006870-f5w6fw6q 1459 10 . . . cord-006870-f5w6fw6q 1460 1 Length length NN cord-006870-f5w6fw6q 1460 2 of of IN cord-006870-f5w6fw6q 1460 3 stay stay NN cord-006870-f5w6fw6q 1460 4 and and CC cord-006870-f5w6fw6q 1460 5 total total JJ cord-006870-f5w6fw6q 1460 6 charges charge NNS cord-006870-f5w6fw6q 1460 7 were be VBD cord-006870-f5w6fw6q 1460 8 also also RB cord-006870-f5w6fw6q 1460 9 examined examine VBN cord-006870-f5w6fw6q 1460 10 as as IN cord-006870-f5w6fw6q 1460 11 resource resource NN cord-006870-f5w6fw6q 1460 12 utilization utilization NN cord-006870-f5w6fw6q 1460 13 measures measure NNS cord-006870-f5w6fw6q 1460 14 . . . cord-006870-f5w6fw6q 1461 1 Of of IN cord-006870-f5w6fw6q 1461 2 _SP cord-006870-f5w6fw6q 1461 3 Obesity Obesity NNP cord-006870-f5w6fw6q 1461 4 is be VBZ cord-006870-f5w6fw6q 1461 5 a a DT cord-006870-f5w6fw6q 1461 6 major major JJ cord-006870-f5w6fw6q 1461 7 health health NN cord-006870-f5w6fw6q 1461 8 care care NN cord-006870-f5w6fw6q 1461 9 burden burden NN cord-006870-f5w6fw6q 1461 10 as as IN cord-006870-f5w6fw6q 1461 11 evidenced evidence VBN cord-006870-f5w6fw6q 1461 12 by by IN cord-006870-f5w6fw6q 1461 13 higher high JJR cord-006870-f5w6fw6q 1461 14 resources resource NNS cord-006870-f5w6fw6q 1461 15 utilization utilization NN cord-006870-f5w6fw6q 1461 16 . . . cord-006870-f5w6fw6q 1462 1 Counterintuitively counterintuitively RB cord-006870-f5w6fw6q 1462 2 , , , cord-006870-f5w6fw6q 1462 3 obesity obesity NN cord-006870-f5w6fw6q 1462 4 appears appear VBZ cord-006870-f5w6fw6q 1462 5 to to TO cord-006870-f5w6fw6q 1462 6 be be VB cord-006870-f5w6fw6q 1462 7 associated associate VBN cord-006870-f5w6fw6q 1462 8 with with IN cord-006870-f5w6fw6q 1462 9 lower low JJR cord-006870-f5w6fw6q 1462 10 in in IN cord-006870-f5w6fw6q 1462 11 - - HYPH cord-006870-f5w6fw6q 1462 12 hospital hospital NN cord-006870-f5w6fw6q 1462 13 mortality mortality NN cord-006870-f5w6fw6q 1462 14 in in IN cord-006870-f5w6fw6q 1462 15 ICH ICH NNP cord-006870-f5w6fw6q 1462 16 patients patient NNS cord-006870-f5w6fw6q 1462 17 . . . cord-006870-f5w6fw6q 1463 1 One one CD cord-006870-f5w6fw6q 1463 2 possible possible JJ cord-006870-f5w6fw6q 1463 3 physiological physiological JJ cord-006870-f5w6fw6q 1463 4 basis basis NN cord-006870-f5w6fw6q 1463 5 for for IN cord-006870-f5w6fw6q 1463 6 this this DT cord-006870-f5w6fw6q 1463 7 could could MD cord-006870-f5w6fw6q 1463 8 be be VB cord-006870-f5w6fw6q 1463 9 that that IN cord-006870-f5w6fw6q 1463 10 the the DT cord-006870-f5w6fw6q 1463 11 higher high JJR cord-006870-f5w6fw6q 1463 12 LDL ldl NN cord-006870-f5w6fw6q 1463 13 levels level NNS cord-006870-f5w6fw6q 1463 14 on on IN cord-006870-f5w6fw6q 1463 15 presentation presentation NN cord-006870-f5w6fw6q 1463 16 result result NN cord-006870-f5w6fw6q 1463 17 in in IN cord-006870-f5w6fw6q 1463 18 a a DT cord-006870-f5w6fw6q 1463 19 lower low JJR cord-006870-f5w6fw6q 1463 20 likelihood likelihood NN cord-006870-f5w6fw6q 1463 21 of of IN cord-006870-f5w6fw6q 1463 22 hematoma hematoma NN cord-006870-f5w6fw6q 1463 23 expansion expansion NN cord-006870-f5w6fw6q 1463 24 . . . cord-006870-f5w6fw6q 1464 1 Recent recent JJ cord-006870-f5w6fw6q 1464 2 short short JJ cord-006870-f5w6fw6q 1464 3 - - HYPH cord-006870-f5w6fw6q 1464 4 term term NN cord-006870-f5w6fw6q 1464 5 outcome outcome NN cord-006870-f5w6fw6q 1464 6 analysis analysis NN cord-006870-f5w6fw6q 1464 7 indicates indicate VBZ cord-006870-f5w6fw6q 1464 8 association association NNP cord-006870-f5w6fw6q 1464 9 of of IN cord-006870-f5w6fw6q 1464 10 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1464 11 intraventricular intraventricular JJ cord-006870-f5w6fw6q 1464 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1464 13 ( ( -LRB- cord-006870-f5w6fw6q 1464 14 IVH IVH NNP cord-006870-f5w6fw6q 1464 15 ) ) -RRB- cord-006870-f5w6fw6q 1465 1 related relate VBN cord-006870-f5w6fw6q 1465 2 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 1465 3 with with IN cord-006870-f5w6fw6q 1465 4 incontinence incontinence NN cord-006870-f5w6fw6q 1465 5 and and CC cord-006870-f5w6fw6q 1465 6 gait gait JJ cord-006870-f5w6fw6q 1465 7 dysfunction dysfunction NN cord-006870-f5w6fw6q 1465 8 . . . cord-006870-f5w6fw6q 1466 1 We -PRON- PRP cord-006870-f5w6fw6q 1466 2 explore explore VBP cord-006870-f5w6fw6q 1466 3 the the DT cord-006870-f5w6fw6q 1466 4 association association NN cord-006870-f5w6fw6q 1466 5 of of IN cord-006870-f5w6fw6q 1466 6 hydrocephalus hydrocephalus NNP cord-006870-f5w6fw6q 1466 7 scores scores NNPS cord-006870-f5w6fw6q 1466 8 , , , cord-006870-f5w6fw6q 1466 9 intraventricular intraventricular NNP cord-006870-f5w6fw6q 1466 10 alteplase alteplase NN cord-006870-f5w6fw6q 1466 11 and and CC cord-006870-f5w6fw6q 1466 12 clinical clinical JJ cord-006870-f5w6fw6q 1466 13 variables variable NNS cord-006870-f5w6fw6q 1466 14 with with IN cord-006870-f5w6fw6q 1466 15 these these DT cord-006870-f5w6fw6q 1466 16 outcomes outcome NNS cord-006870-f5w6fw6q 1466 17 at at IN cord-006870-f5w6fw6q 1466 18 long long JJ cord-006870-f5w6fw6q 1466 19 term term NN cord-006870-f5w6fw6q 1466 20 follow follow VB cord-006870-f5w6fw6q 1466 21 up up RP cord-006870-f5w6fw6q 1466 22 in in IN cord-006870-f5w6fw6q 1466 23 survivors survivor NNS cord-006870-f5w6fw6q 1466 24 from from IN cord-006870-f5w6fw6q 1466 25 the the DT cord-006870-f5w6fw6q 1466 26 CLEAR clear JJ cord-006870-f5w6fw6q 1466 27 III III NNP cord-006870-f5w6fw6q 1466 28 trial trial NN cord-006870-f5w6fw6q 1466 29 . . . cord-006870-f5w6fw6q 1467 1 CLEAR CLEAR NNP cord-006870-f5w6fw6q 1467 2 III III NNP cord-006870-f5w6fw6q 1467 3 , , , cord-006870-f5w6fw6q 1467 4 a a DT cord-006870-f5w6fw6q 1467 5 randomized randomized JJ cord-006870-f5w6fw6q 1467 6 , , , cord-006870-f5w6fw6q 1467 7 multi multi JJ cord-006870-f5w6fw6q 1467 8 - - JJ cord-006870-f5w6fw6q 1467 9 center center JJ cord-006870-f5w6fw6q 1467 10 , , , cord-006870-f5w6fw6q 1467 11 double double JJ cord-006870-f5w6fw6q 1467 12 - - HYPH cord-006870-f5w6fw6q 1467 13 blinded blinded JJ cord-006870-f5w6fw6q 1467 14 , , , cord-006870-f5w6fw6q 1467 15 placebo placebo NN cord-006870-f5w6fw6q 1467 16 - - HYPH cord-006870-f5w6fw6q 1467 17 controlled control VBN cord-006870-f5w6fw6q 1467 18 trial trial NN cord-006870-f5w6fw6q 1467 19 was be VBD cord-006870-f5w6fw6q 1467 20 conducted conduct VBN cord-006870-f5w6fw6q 1467 21 to to TO cord-006870-f5w6fw6q 1467 22 determine determine VB cord-006870-f5w6fw6q 1467 23 if if IN cord-006870-f5w6fw6q 1467 24 pragmatically pragmatically RB cord-006870-f5w6fw6q 1467 25 employed employ VBN cord-006870-f5w6fw6q 1467 26 external external JJ cord-006870-f5w6fw6q 1467 27 ventricular ventricular JJ cord-006870-f5w6fw6q 1467 28 drainage drainage NN cord-006870-f5w6fw6q 1467 29 ( ( -LRB- cord-006870-f5w6fw6q 1467 30 EVD EVD NNP cord-006870-f5w6fw6q 1467 31 ) ) -RRB- cord-006870-f5w6fw6q 1467 32 plus plus CC cord-006870-f5w6fw6q 1467 33 intraventricular intraventricular NNP cord-006870-f5w6fw6q 1467 34 alteplase alteplase NNP cord-006870-f5w6fw6q 1467 35 improved improve VBD cord-006870-f5w6fw6q 1467 36 outcome outcome NN cord-006870-f5w6fw6q 1467 37 , , , cord-006870-f5w6fw6q 1467 38 in in IN cord-006870-f5w6fw6q 1467 39 comparison comparison NN cord-006870-f5w6fw6q 1467 40 to to IN cord-006870-f5w6fw6q 1467 41 EVD EVD NNP cord-006870-f5w6fw6q 1467 42 plus plus CC cord-006870-f5w6fw6q 1467 43 saline saline NN cord-006870-f5w6fw6q 1467 44 in in IN cord-006870-f5w6fw6q 1467 45 patients patient NNS cord-006870-f5w6fw6q 1467 46 with with IN cord-006870-f5w6fw6q 1467 47 IVH IVH NNP cord-006870-f5w6fw6q 1467 48 causing cause VBG cord-006870-f5w6fw6q 1467 49 obstructive obstructive JJ cord-006870-f5w6fw6q 1467 50 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 1467 51 . . . cord-006870-f5w6fw6q 1468 1 We -PRON- PRP cord-006870-f5w6fw6q 1468 2 assessed assess VBD cord-006870-f5w6fw6q 1468 3 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 1468 4 scores score NNS cord-006870-f5w6fw6q 1468 5 on on IN cord-006870-f5w6fw6q 1468 6 survivors survivor NNS cord-006870-f5w6fw6q 1468 7 at at IN cord-006870-f5w6fw6q 1468 8 diagnosis diagnosis NN cord-006870-f5w6fw6q 1468 9 , , , cord-006870-f5w6fw6q 1468 10 days day NNS cord-006870-f5w6fw6q 1468 11 30 30 CD cord-006870-f5w6fw6q 1468 12 and and CC cord-006870-f5w6fw6q 1468 13 365 365 CD cord-006870-f5w6fw6q 1468 14 . . . cord-006870-f5w6fw6q 1469 1 Incontinence incontinence NN cord-006870-f5w6fw6q 1469 2 and and CC cord-006870-f5w6fw6q 1469 3 dysmobility dysmobility NN cord-006870-f5w6fw6q 1469 4 were be VBD cord-006870-f5w6fw6q 1469 5 defined define VBN cord-006870-f5w6fw6q 1469 6 using use VBG cord-006870-f5w6fw6q 1469 7 12-month 12-month JJ cord-006870-f5w6fw6q 1469 8 Barthel Barthel NNP cord-006870-f5w6fw6q 1469 9 Index Index NNP cord-006870-f5w6fw6q 1469 10 subscores subscore NNS cord-006870-f5w6fw6q 1469 11 ( ( -LRB- cord-006870-f5w6fw6q 1469 12 < < NNP cord-006870-f5w6fw6q 1469 13 10 10 CD cord-006870-f5w6fw6q 1469 14 for for IN cord-006870-f5w6fw6q 1469 15 bladder bladder NN cord-006870-f5w6fw6q 1469 16 and and CC cord-006870-f5w6fw6q 1469 17 < < XX cord-006870-f5w6fw6q 1469 18 15 15 CD cord-006870-f5w6fw6q 1469 19 for for IN cord-006870-f5w6fw6q 1469 20 mobility mobility NN cord-006870-f5w6fw6q 1469 21 , , , cord-006870-f5w6fw6q 1469 22 respectively respectively RB cord-006870-f5w6fw6q 1469 23 ) ) -RRB- cord-006870-f5w6fw6q 1469 24 . . . cord-006870-f5w6fw6q 1470 1 Outcome outcome NN cord-006870-f5w6fw6q 1470 2 measures measure NNS cord-006870-f5w6fw6q 1470 3 were be VBD cord-006870-f5w6fw6q 1470 4 predictors predictor NNS cord-006870-f5w6fw6q 1470 5 of of IN cord-006870-f5w6fw6q 1470 6 incontinence incontinence NN cord-006870-f5w6fw6q 1470 7 and and CC cord-006870-f5w6fw6q 1470 8 gait gait JJ cord-006870-f5w6fw6q 1470 9 dysmobility dysmobility NN cord-006870-f5w6fw6q 1470 10 at at IN cord-006870-f5w6fw6q 1470 11 1 1 CD cord-006870-f5w6fw6q 1470 12 year year NN cord-006870-f5w6fw6q 1470 13 after after IN cord-006870-f5w6fw6q 1470 14 ICH ICH NNP cord-006870-f5w6fw6q 1470 15 . . . cord-006870-f5w6fw6q 1470 16 _SP cord-006870-f5w6fw6q 1471 1 This this DT cord-006870-f5w6fw6q 1471 2 prospective prospective JJ cord-006870-f5w6fw6q 1471 3 observational observational JJ cord-006870-f5w6fw6q 1471 4 study study NN cord-006870-f5w6fw6q 1471 5 analyzed analyze VBD cord-006870-f5w6fw6q 1471 6 consecutive consecutive JJ cord-006870-f5w6fw6q 1471 7 ICH ICH NNP cord-006870-f5w6fw6q 1471 8 - - HYPH cord-006870-f5w6fw6q 1471 9 patients patient NNS cord-006870-f5w6fw6q 1471 10 ( ( -LRB- cord-006870-f5w6fw6q 1471 11 n=246 n=246 NNP cord-006870-f5w6fw6q 1471 12 ) ) -RRB- cord-006870-f5w6fw6q 1471 13 treated treat VBN cord-006870-f5w6fw6q 1471 14 at at IN cord-006870-f5w6fw6q 1471 15 the the DT cord-006870-f5w6fw6q 1471 16 neurological neurological JJ cord-006870-f5w6fw6q 1471 17 and and CC cord-006870-f5w6fw6q 1471 18 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 1471 19 departments department NNS cord-006870-f5w6fw6q 1471 20 of of IN cord-006870-f5w6fw6q 1471 21 the the DT cord-006870-f5w6fw6q 1471 22 University University NNP cord-006870-f5w6fw6q 1471 23 - - HYPH cord-006870-f5w6fw6q 1471 24 hospital hospital NN cord-006870-f5w6fw6q 1471 25 Erlangen Erlangen NNP cord-006870-f5w6fw6q 1471 26 , , , cord-006870-f5w6fw6q 1471 27 Germany Germany NNP cord-006870-f5w6fw6q 1471 28 over over IN cord-006870-f5w6fw6q 1471 29 a a DT cord-006870-f5w6fw6q 1471 30 21month 21month JJ cord-006870-f5w6fw6q 1471 31 inclusion inclusion NN cord-006870-f5w6fw6q 1471 32 period period NN cord-006870-f5w6fw6q 1471 33 ( ( -LRB- cord-006870-f5w6fw6q 1471 34 05/2013 05/2013 CD cord-006870-f5w6fw6q 1471 35 - - SYM cord-006870-f5w6fw6q 1471 36 01/2015 01/2015 CD cord-006870-f5w6fw6q 1471 37 ) ) -RRB- cord-006870-f5w6fw6q 1471 38 . . . cord-006870-f5w6fw6q 1472 1 We -PRON- PRP cord-006870-f5w6fw6q 1472 2 analyzed analyze VBD cord-006870-f5w6fw6q 1472 3 the the DT cord-006870-f5w6fw6q 1472 4 influence influence NN cord-006870-f5w6fw6q 1472 5 of of IN cord-006870-f5w6fw6q 1472 6 patient patient JJ cord-006870-f5w6fw6q 1472 7 characteristics characteristic NNS cord-006870-f5w6fw6q 1472 8 , , , cord-006870-f5w6fw6q 1472 9 inhospital inhospital NNP cord-006870-f5w6fw6q 1472 10 measures measure NNS cord-006870-f5w6fw6q 1472 11 and and CC cord-006870-f5w6fw6q 1472 12 functional functional JJ cord-006870-f5w6fw6q 1472 13 status status NN cord-006870-f5w6fw6q 1472 14 on on IN cord-006870-f5w6fw6q 1472 15 treatment treatment NN cord-006870-f5w6fw6q 1472 16 recommendations recommendation NNS cord-006870-f5w6fw6q 1472 17 and and CC cord-006870-f5w6fw6q 1472 18 on on IN cord-006870-f5w6fw6q 1472 19 OAC OAC NNP cord-006870-f5w6fw6q 1472 20 initiation initiation NN cord-006870-f5w6fw6q 1472 21 during during IN cord-006870-f5w6fw6q 1472 22 12-month 12-month JJ cord-006870-f5w6fw6q 1472 23 follow follow NN cord-006870-f5w6fw6q 1472 24 - - HYPH cord-006870-f5w6fw6q 1472 25 up up NN cord-006870-f5w6fw6q 1472 26 . . . cord-006870-f5w6fw6q 1472 27 _SP cord-006870-f5w6fw6q 1473 1 Clear clear JJ cord-006870-f5w6fw6q 1473 2 treatment treatment NN cord-006870-f5w6fw6q 1473 3 recommendations recommendation NNS cord-006870-f5w6fw6q 1473 4 by by IN cord-006870-f5w6fw6q 1473 5 attending attend VBG cord-006870-f5w6fw6q 1473 6 stroke stroke NN cord-006870-f5w6fw6q 1473 7 physicians physician NNS cord-006870-f5w6fw6q 1473 8 seem seem VBP cord-006870-f5w6fw6q 1473 9 necessary necessary JJ cord-006870-f5w6fw6q 1473 10 to to TO cord-006870-f5w6fw6q 1473 11 ensure ensure VB cord-006870-f5w6fw6q 1473 12 OAC OAC NNP cord-006870-f5w6fw6q 1473 13 initiation initiation NN cord-006870-f5w6fw6q 1473 14 after after IN cord-006870-f5w6fw6q 1473 15 ICH ICH NNP cord-006870-f5w6fw6q 1473 16 . . . cord-006870-f5w6fw6q 1474 1 OAC OAC NNP cord-006870-f5w6fw6q 1474 2 showed show VBD cord-006870-f5w6fw6q 1474 3 beneficial beneficial JJ cord-006870-f5w6fw6q 1474 4 associations association NNS cord-006870-f5w6fw6q 1474 5 ; ; : cord-006870-f5w6fw6q 1474 6 however however RB cord-006870-f5w6fw6q 1474 7 data datum NNS cord-006870-f5w6fw6q 1474 8 here here RB cord-006870-f5w6fw6q 1474 9 suggests suggest VBZ cord-006870-f5w6fw6q 1474 10 the the DT cord-006870-f5w6fw6q 1474 11 presence presence NN cord-006870-f5w6fw6q 1474 12 of of IN cord-006870-f5w6fw6q 1474 13 an an DT cord-006870-f5w6fw6q 1474 14 indication indication NN cord-006870-f5w6fw6q 1474 15 bias bias NN cord-006870-f5w6fw6q 1474 16 introduced introduce VBN cord-006870-f5w6fw6q 1474 17 by by IN cord-006870-f5w6fw6q 1474 18 treatment treatment NN cord-006870-f5w6fw6q 1474 19 recommendations recommendation NNS cord-006870-f5w6fw6q 1474 20 and and CC cord-006870-f5w6fw6q 1474 21 outpatient outpatient NN cord-006870-f5w6fw6q 1474 22 care care NN cord-006870-f5w6fw6q 1474 23 during during IN cord-006870-f5w6fw6q 1474 24 follow follow NN cord-006870-f5w6fw6q 1474 25 - - HYPH cord-006870-f5w6fw6q 1474 26 up up NN cord-006870-f5w6fw6q 1474 27 . . . cord-006870-f5w6fw6q 1475 1 Therefore therefore RB cord-006870-f5w6fw6q 1475 2 , , , cord-006870-f5w6fw6q 1475 3 observed observe VBD cord-006870-f5w6fw6q 1475 4 association association NN cord-006870-f5w6fw6q 1475 5 with with IN cord-006870-f5w6fw6q 1475 6 age age NN cord-006870-f5w6fw6q 1475 7 and and CC cord-006870-f5w6fw6q 1475 8 functional functional JJ cord-006870-f5w6fw6q 1475 9 status status NN cord-006870-f5w6fw6q 1475 10 might may MD cord-006870-f5w6fw6q 1475 11 affect affect VB cord-006870-f5w6fw6q 1475 12 unadjusted unadjusted JJ cord-006870-f5w6fw6q 1475 13 analyses analysis NNS cord-006870-f5w6fw6q 1475 14 . . . cord-006870-f5w6fw6q 1476 1 Although although IN cord-006870-f5w6fw6q 1476 2 recently recently RB cord-006870-f5w6fw6q 1476 3 , , , cord-006870-f5w6fw6q 1476 4 Non non JJ cord-006870-f5w6fw6q 1476 5 - - NN cord-006870-f5w6fw6q 1476 6 vitamin vitamin NN cord-006870-f5w6fw6q 1476 7 K K NNP cord-006870-f5w6fw6q 1476 8 Antagonist Antagonist NNP cord-006870-f5w6fw6q 1476 9 Oral oral JJ cord-006870-f5w6fw6q 1476 10 Anticoagulants anticoagulant NNS cord-006870-f5w6fw6q 1476 11 ( ( -LRB- cord-006870-f5w6fw6q 1476 12 NOACs noac NNS cord-006870-f5w6fw6q 1476 13 ) ) -RRB- cord-006870-f5w6fw6q 1476 14 therapy therapy NN cord-006870-f5w6fw6q 1476 15 in in IN cord-006870-f5w6fw6q 1476 16 patients patient NNS cord-006870-f5w6fw6q 1476 17 with with IN cord-006870-f5w6fw6q 1476 18 non non JJ cord-006870-f5w6fw6q 1476 19 valvular valvular JJ cord-006870-f5w6fw6q 1476 20 atrial atrial JJ cord-006870-f5w6fw6q 1476 21 fibrillation fibrillation NN cord-006870-f5w6fw6q 1476 22 have have VBP cord-006870-f5w6fw6q 1476 23 half half PDT cord-006870-f5w6fw6q 1476 24 the the DT cord-006870-f5w6fw6q 1476 25 incidence incidence NN cord-006870-f5w6fw6q 1476 26 of of IN cord-006870-f5w6fw6q 1476 27 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1476 28 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1476 29 ( ( -LRB- cord-006870-f5w6fw6q 1476 30 ICH ICH NNP cord-006870-f5w6fw6q 1476 31 ) ) -RRB- cord-006870-f5w6fw6q 1476 32 compared compare VBN cord-006870-f5w6fw6q 1476 33 to to IN cord-006870-f5w6fw6q 1476 34 warfarin warfarin NN cord-006870-f5w6fw6q 1476 35 . . . cord-006870-f5w6fw6q 1477 1 However however RB cord-006870-f5w6fw6q 1477 2 , , , cord-006870-f5w6fw6q 1477 3 it -PRON- PRP cord-006870-f5w6fw6q 1477 4 would would MD cord-006870-f5w6fw6q 1477 5 be be VB cord-006870-f5w6fw6q 1477 6 still still RB cord-006870-f5w6fw6q 1477 7 controversial controversial JJ cord-006870-f5w6fw6q 1477 8 subject subject NN cord-006870-f5w6fw6q 1477 9 that that DT cord-006870-f5w6fw6q 1477 10 outcome outcome NN cord-006870-f5w6fw6q 1477 11 of of IN cord-006870-f5w6fw6q 1477 12 NOAC NOAC NNP cord-006870-f5w6fw6q 1477 13 - - HYPH cord-006870-f5w6fw6q 1477 14 associated associate VBN cord-006870-f5w6fw6q 1477 15 ICH ICH NNP cord-006870-f5w6fw6q 1477 16 ( ( -LRB- cord-006870-f5w6fw6q 1477 17 NICH NICH NNP cord-006870-f5w6fw6q 1477 18 ) ) -RRB- cord-006870-f5w6fw6q 1477 19 might may MD cord-006870-f5w6fw6q 1477 20 be be VB cord-006870-f5w6fw6q 1477 21 worse bad JJR cord-006870-f5w6fw6q 1477 22 or or CC cord-006870-f5w6fw6q 1477 23 better well JJR cord-006870-f5w6fw6q 1477 24 than than IN cord-006870-f5w6fw6q 1477 25 warfarin warfarin NN cord-006870-f5w6fw6q 1477 26 - - HYPH cord-006870-f5w6fw6q 1477 27 associated associate VBN cord-006870-f5w6fw6q 1477 28 ICH ICH NNP cord-006870-f5w6fw6q 1477 29 ( ( -LRB- cord-006870-f5w6fw6q 1477 30 WICH wich RB cord-006870-f5w6fw6q 1477 31 ) ) -RRB- cord-006870-f5w6fw6q 1477 32 . . . cord-006870-f5w6fw6q 1478 1 In in IN cord-006870-f5w6fw6q 1478 2 this this DT cord-006870-f5w6fw6q 1478 3 study study NN cord-006870-f5w6fw6q 1478 4 , , , cord-006870-f5w6fw6q 1478 5 we -PRON- PRP cord-006870-f5w6fw6q 1478 6 investigated investigate VBD cord-006870-f5w6fw6q 1478 7 clinical clinical JJ cord-006870-f5w6fw6q 1478 8 outcome outcome NN cord-006870-f5w6fw6q 1478 9 and and CC cord-006870-f5w6fw6q 1478 10 radiological radiological JJ cord-006870-f5w6fw6q 1478 11 finding finding NN cord-006870-f5w6fw6q 1478 12 of of IN cord-006870-f5w6fw6q 1478 13 ICH ICH NNP cord-006870-f5w6fw6q 1478 14 between between IN cord-006870-f5w6fw6q 1478 15 two two CD cord-006870-f5w6fw6q 1478 16 different different JJ cord-006870-f5w6fw6q 1478 17 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 1478 18 treatments treatment NNS cord-006870-f5w6fw6q 1478 19 . . . cord-006870-f5w6fw6q 1479 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 1479 2 review review NN cord-006870-f5w6fw6q 1479 3 of of IN cord-006870-f5w6fw6q 1479 4 medical medical JJ cord-006870-f5w6fw6q 1479 5 records record NNS cord-006870-f5w6fw6q 1479 6 was be VBD cord-006870-f5w6fw6q 1479 7 performed perform VBN cord-006870-f5w6fw6q 1479 8 for for IN cord-006870-f5w6fw6q 1479 9 1,197 1,197 CD cord-006870-f5w6fw6q 1479 10 patients patient NNS cord-006870-f5w6fw6q 1479 11 who who WP cord-006870-f5w6fw6q 1479 12 admitted admit VBD cord-006870-f5w6fw6q 1479 13 with with IN cord-006870-f5w6fw6q 1479 14 ICH ICH NNP cord-006870-f5w6fw6q 1479 15 from from IN cord-006870-f5w6fw6q 1479 16 2003 2003 CD cord-006870-f5w6fw6q 1479 17 to to IN cord-006870-f5w6fw6q 1479 18 2016 2016 CD cord-006870-f5w6fw6q 1479 19 in in IN cord-006870-f5w6fw6q 1479 20 Seoul Seoul NNP cord-006870-f5w6fw6q 1479 21 National National NNP cord-006870-f5w6fw6q 1479 22 University University NNP cord-006870-f5w6fw6q 1479 23 Bundang Bundang NNP cord-006870-f5w6fw6q 1479 24 Hospital Hospital NNP cord-006870-f5w6fw6q 1479 25 . . . cord-006870-f5w6fw6q 1480 1 Clinical clinical JJ cord-006870-f5w6fw6q 1480 2 characteristics characteristic NNS cord-006870-f5w6fw6q 1480 3 , , , cord-006870-f5w6fw6q 1480 4 functional functional JJ cord-006870-f5w6fw6q 1480 5 outcome outcome NN cord-006870-f5w6fw6q 1480 6 , , , cord-006870-f5w6fw6q 1480 7 location location NN cord-006870-f5w6fw6q 1480 8 and and CC cord-006870-f5w6fw6q 1480 9 volume volume NN cord-006870-f5w6fw6q 1480 10 of of IN cord-006870-f5w6fw6q 1480 11 ICH ICH NNP cord-006870-f5w6fw6q 1480 12 , , , cord-006870-f5w6fw6q 1480 13 and and CC cord-006870-f5w6fw6q 1480 14 all all DT cord-006870-f5w6fw6q 1480 15 - - HYPH cord-006870-f5w6fw6q 1480 16 cause cause NN cord-006870-f5w6fw6q 1480 17 mortality mortality NN cord-006870-f5w6fw6q 1480 18 within within IN cord-006870-f5w6fw6q 1480 19 90 90 CD cord-006870-f5w6fw6q 1480 20 days day NNS cord-006870-f5w6fw6q 1480 21 were be VBD cord-006870-f5w6fw6q 1480 22 analyzed analyze VBN cord-006870-f5w6fw6q 1480 23 . . . cord-006870-f5w6fw6q 1481 1 Among among IN cord-006870-f5w6fw6q 1481 2 those those DT cord-006870-f5w6fw6q 1481 3 patients patient NNS cord-006870-f5w6fw6q 1481 4 , , , cord-006870-f5w6fw6q 1481 5 47 47 CD cord-006870-f5w6fw6q 1481 6 patients patient NNS cord-006870-f5w6fw6q 1481 7 with with IN cord-006870-f5w6fw6q 1481 8 WICH WICH NNP cord-006870-f5w6fw6q 1481 9 and and CC cord-006870-f5w6fw6q 1481 10 8 8 CD cord-006870-f5w6fw6q 1481 11 patients patient NNS cord-006870-f5w6fw6q 1481 12 with with IN cord-006870-f5w6fw6q 1481 13 NICH NICH NNP cord-006870-f5w6fw6q 1481 14 were be VBD cord-006870-f5w6fw6q 1481 15 included include VBN cord-006870-f5w6fw6q 1481 16 . . . cord-006870-f5w6fw6q 1482 1 Lesion lesion NN cord-006870-f5w6fw6q 1482 2 location location NN cord-006870-f5w6fw6q 1482 3 was be VBD cord-006870-f5w6fw6q 1482 4 common common JJ cord-006870-f5w6fw6q 1482 5 in in IN cord-006870-f5w6fw6q 1482 6 supratentorial supratentorial NNP cord-006870-f5w6fw6q 1482 7 deep deep JJ cord-006870-f5w6fw6q 1482 8 area area NN cord-006870-f5w6fw6q 1482 9 ( ( -LRB- cord-006870-f5w6fw6q 1482 10 50.0 50.0 CD cord-006870-f5w6fw6q 1482 11 % % NN cord-006870-f5w6fw6q 1482 12 , , , cord-006870-f5w6fw6q 1482 13 44.7 44.7 CD cord-006870-f5w6fw6q 1482 14 % % NN cord-006870-f5w6fw6q 1482 15 ) ) -RRB- cord-006870-f5w6fw6q 1482 16 , , , cord-006870-f5w6fw6q 1482 17 lobar lobar NNP cord-006870-f5w6fw6q 1482 18 area area NN cord-006870-f5w6fw6q 1482 19 ( ( -LRB- cord-006870-f5w6fw6q 1482 20 37.5 37.5 CD cord-006870-f5w6fw6q 1482 21 % % NN cord-006870-f5w6fw6q 1482 22 , , , cord-006870-f5w6fw6q 1482 23 31.9 31.9 CD cord-006870-f5w6fw6q 1482 24 % % NN cord-006870-f5w6fw6q 1482 25 ) ) -RRB- cord-006870-f5w6fw6q 1482 26 and and CC cord-006870-f5w6fw6q 1482 27 brainstem brainstem NN cord-006870-f5w6fw6q 1482 28 and and CC cord-006870-f5w6fw6q 1482 29 cerebellum cerebellum NN cord-006870-f5w6fw6q 1482 30 ( ( -LRB- cord-006870-f5w6fw6q 1482 31 12.5 12.5 CD cord-006870-f5w6fw6q 1482 32 % % NN cord-006870-f5w6fw6q 1482 33 , , , cord-006870-f5w6fw6q 1482 34 23.4 23.4 CD cord-006870-f5w6fw6q 1482 35 % % NN cord-006870-f5w6fw6q 1482 36 ) ) -RRB- cord-006870-f5w6fw6q 1482 37 in in IN cord-006870-f5w6fw6q 1482 38 the the DT cord-006870-f5w6fw6q 1482 39 NICH NICH NNP cord-006870-f5w6fw6q 1482 40 and and CC cord-006870-f5w6fw6q 1482 41 WICH WICH NNP cord-006870-f5w6fw6q 1482 42 group group NN cord-006870-f5w6fw6q 1482 43 , , , cord-006870-f5w6fw6q 1482 44 respectively respectively RB cord-006870-f5w6fw6q 1482 45 . . . cord-006870-f5w6fw6q 1483 1 No no DT cord-006870-f5w6fw6q 1483 2 significant significant JJ cord-006870-f5w6fw6q 1483 3 difference difference NN cord-006870-f5w6fw6q 1483 4 found find VBN cord-006870-f5w6fw6q 1483 5 in in IN cord-006870-f5w6fw6q 1483 6 initial initial JJ cord-006870-f5w6fw6q 1483 7 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1483 8 ( ( -LRB- cord-006870-f5w6fw6q 1483 9 15.5 15.5 CD cord-006870-f5w6fw6q 1483 10 vs vs IN cord-006870-f5w6fw6q 1483 11 10 10 CD cord-006870-f5w6fw6q 1483 12 ) ) -RRB- cord-006870-f5w6fw6q 1483 13 , , , cord-006870-f5w6fw6q 1483 14 discharge discharge NN cord-006870-f5w6fw6q 1483 15 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1483 16 ( ( -LRB- cord-006870-f5w6fw6q 1483 17 16.5 16.5 CD cord-006870-f5w6fw6q 1483 18 vs vs IN cord-006870-f5w6fw6q 1483 19 8) 8) NNP cord-006870-f5w6fw6q 1483 20 , , , cord-006870-f5w6fw6q 1483 21 mRS mRS '' cord-006870-f5w6fw6q 1483 22 ( ( -LRB- cord-006870-f5w6fw6q 1483 23 0 0 CD cord-006870-f5w6fw6q 1483 24 to to IN cord-006870-f5w6fw6q 1483 25 2 2 CD cord-006870-f5w6fw6q 1483 26 ) ) -RRB- cord-006870-f5w6fw6q 1483 27 at at IN cord-006870-f5w6fw6q 1483 28 discharge discharge NN cord-006870-f5w6fw6q 1483 29 ( ( -LRB- cord-006870-f5w6fw6q 1483 30 14.9 14.9 CD cord-006870-f5w6fw6q 1483 31 % % NN cord-006870-f5w6fw6q 1483 32 vs vs IN cord-006870-f5w6fw6q 1483 33 25.0 25.0 CD cord-006870-f5w6fw6q 1483 34 % % NN cord-006870-f5w6fw6q 1483 35 ) ) -RRB- cord-006870-f5w6fw6q 1483 36 , , , cord-006870-f5w6fw6q 1483 37 mRS mRS '' cord-006870-f5w6fw6q 1483 38 ( ( -LRB- cord-006870-f5w6fw6q 1483 39 0 0 CD cord-006870-f5w6fw6q 1483 40 to to IN cord-006870-f5w6fw6q 1483 41 3 3 CD cord-006870-f5w6fw6q 1483 42 ) ) -RRB- cord-006870-f5w6fw6q 1483 43 at at IN cord-006870-f5w6fw6q 1483 44 discharge discharge NN cord-006870-f5w6fw6q 1483 45 ( ( -LRB- cord-006870-f5w6fw6q 1483 46 36.2 36.2 CD cord-006870-f5w6fw6q 1483 47 % % NN cord-006870-f5w6fw6q 1483 48 vs vs IN cord-006870-f5w6fw6q 1483 49 25.0 25.0 CD cord-006870-f5w6fw6q 1483 50 ) ) -RRB- cord-006870-f5w6fw6q 1483 51 , , , cord-006870-f5w6fw6q 1483 52 mRS mRS '' cord-006870-f5w6fw6q 1483 53 ( ( -LRB- cord-006870-f5w6fw6q 1483 54 0 0 CD cord-006870-f5w6fw6q 1483 55 to to IN cord-006870-f5w6fw6q 1483 56 2 2 CD cord-006870-f5w6fw6q 1483 57 ) ) -RRB- cord-006870-f5w6fw6q 1483 58 at at IN cord-006870-f5w6fw6q 1483 59 90 90 CD cord-006870-f5w6fw6q 1483 60 days day NNS cord-006870-f5w6fw6q 1483 61 ( ( -LRB- cord-006870-f5w6fw6q 1483 62 25.5 25.5 CD cord-006870-f5w6fw6q 1483 63 % % NN cord-006870-f5w6fw6q 1483 64 vs vs IN cord-006870-f5w6fw6q 1483 65 12.5 12.5 CD cord-006870-f5w6fw6q 1483 66 ) ) -RRB- cord-006870-f5w6fw6q 1483 67 and and CC cord-006870-f5w6fw6q 1483 68 mRS mrs XX cord-006870-f5w6fw6q 1483 69 ( ( -LRB- cord-006870-f5w6fw6q 1483 70 0 0 CD cord-006870-f5w6fw6q 1483 71 to to IN cord-006870-f5w6fw6q 1483 72 3 3 CD cord-006870-f5w6fw6q 1483 73 ) ) -RRB- cord-006870-f5w6fw6q 1483 74 at at IN cord-006870-f5w6fw6q 1483 75 90 90 CD cord-006870-f5w6fw6q 1483 76 days day NNS cord-006870-f5w6fw6q 1483 77 ( ( -LRB- cord-006870-f5w6fw6q 1483 78 25.5 25.5 CD cord-006870-f5w6fw6q 1483 79 % % NN cord-006870-f5w6fw6q 1483 80 vs vs IN cord-006870-f5w6fw6q 1483 81 12.5 12.5 CD cord-006870-f5w6fw6q 1483 82 ) ) -RRB- cord-006870-f5w6fw6q 1483 83 in in IN cord-006870-f5w6fw6q 1483 84 NICH NICH NNP cord-006870-f5w6fw6q 1483 85 and and CC cord-006870-f5w6fw6q 1483 86 WICH WICH NNP cord-006870-f5w6fw6q 1483 87 group group NN cord-006870-f5w6fw6q 1483 88 . . . cord-006870-f5w6fw6q 1484 1 We -PRON- PRP cord-006870-f5w6fw6q 1484 2 did do VBD cord-006870-f5w6fw6q 1484 3 not not RB cord-006870-f5w6fw6q 1484 4 find find VB cord-006870-f5w6fw6q 1484 5 any any DT cord-006870-f5w6fw6q 1484 6 difference difference NN cord-006870-f5w6fw6q 1484 7 between between IN cord-006870-f5w6fw6q 1484 8 NICH NICH NNP cord-006870-f5w6fw6q 1484 9 and and CC cord-006870-f5w6fw6q 1484 10 WICH WICH NNP cord-006870-f5w6fw6q 1484 11 for for IN cord-006870-f5w6fw6q 1484 12 allcause allcause NN cord-006870-f5w6fw6q 1484 13 mortality mortality NN cord-006870-f5w6fw6q 1484 14 at at IN cord-006870-f5w6fw6q 1484 15 discharge discharge NN cord-006870-f5w6fw6q 1484 16 ( ( -LRB- cord-006870-f5w6fw6q 1484 17 17 17 CD cord-006870-f5w6fw6q 1484 18 % % NN cord-006870-f5w6fw6q 1484 19 vs vs IN cord-006870-f5w6fw6q 1484 20 0 0 CD cord-006870-f5w6fw6q 1484 21 % % NN cord-006870-f5w6fw6q 1484 22 ) ) -RRB- cord-006870-f5w6fw6q 1484 23 , , , cord-006870-f5w6fw6q 1484 24 90 90 CD cord-006870-f5w6fw6q 1484 25 days day NNS cord-006870-f5w6fw6q 1484 26 ( ( -LRB- cord-006870-f5w6fw6q 1484 27 27.7 27.7 CD cord-006870-f5w6fw6q 1484 28 % % NN cord-006870-f5w6fw6q 1484 29 vs vs IN cord-006870-f5w6fw6q 1484 30 0 0 CD cord-006870-f5w6fw6q 1484 31 % % NN cord-006870-f5w6fw6q 1484 32 ) ) -RRB- cord-006870-f5w6fw6q 1484 33 , , , cord-006870-f5w6fw6q 1484 34 and and CC cord-006870-f5w6fw6q 1484 35 1year 1year NN cord-006870-f5w6fw6q 1484 36 ( ( -LRB- cord-006870-f5w6fw6q 1484 37 34 34 CD cord-006870-f5w6fw6q 1484 38 % % NN cord-006870-f5w6fw6q 1484 39 vs vs IN cord-006870-f5w6fw6q 1484 40 25 25 CD cord-006870-f5w6fw6q 1484 41 % % NN cord-006870-f5w6fw6q 1484 42 ) ) -RRB- cord-006870-f5w6fw6q 1484 43 . . . cord-006870-f5w6fw6q 1485 1 Median median JJ cord-006870-f5w6fw6q 1485 2 baseline baseline NN cord-006870-f5w6fw6q 1485 3 ICH ICH NNP cord-006870-f5w6fw6q 1485 4 volume volume NN cord-006870-f5w6fw6q 1485 5 was be VBD cord-006870-f5w6fw6q 1485 6 not not RB cord-006870-f5w6fw6q 1485 7 significant significant JJ cord-006870-f5w6fw6q 1485 8 difference difference NN cord-006870-f5w6fw6q 1485 9 in in IN cord-006870-f5w6fw6q 1485 10 two two CD cord-006870-f5w6fw6q 1485 11 groups group NNS cord-006870-f5w6fw6q 1485 12 ( ( -LRB- cord-006870-f5w6fw6q 1485 13 3676.2 3676.2 CD cord-006870-f5w6fw6q 1485 14 vs vs IN cord-006870-f5w6fw6q 1485 15 1542.24 1542.24 CD cord-006870-f5w6fw6q 1485 16 ) ) -RRB- cord-006870-f5w6fw6q 1485 17 . . . cord-006870-f5w6fw6q 1486 1 In in IN cord-006870-f5w6fw6q 1486 2 our -PRON- PRP$ cord-006870-f5w6fw6q 1486 3 study study NN cord-006870-f5w6fw6q 1486 4 , , , cord-006870-f5w6fw6q 1486 5 functional functional JJ cord-006870-f5w6fw6q 1486 6 outcome outcome NN cord-006870-f5w6fw6q 1486 7 , , , cord-006870-f5w6fw6q 1486 8 mortality mortality NN cord-006870-f5w6fw6q 1486 9 , , , cord-006870-f5w6fw6q 1486 10 and and CC cord-006870-f5w6fw6q 1486 11 baseline baseline JJ cord-006870-f5w6fw6q 1486 12 ICH ICH NNP cord-006870-f5w6fw6q 1486 13 volume volume NN cord-006870-f5w6fw6q 1486 14 were be VBD cord-006870-f5w6fw6q 1486 15 similar similar JJ cord-006870-f5w6fw6q 1486 16 following follow VBG cord-006870-f5w6fw6q 1486 17 NICH NICH NNP cord-006870-f5w6fw6q 1486 18 and and CC cord-006870-f5w6fw6q 1486 19 WICH WICH NNP cord-006870-f5w6fw6q 1486 20 . . . cord-006870-f5w6fw6q 1487 1 Because because IN cord-006870-f5w6fw6q 1487 2 of of IN cord-006870-f5w6fw6q 1487 3 low low JJ cord-006870-f5w6fw6q 1487 4 statistical statistical JJ cord-006870-f5w6fw6q 1487 5 power power NN cord-006870-f5w6fw6q 1487 6 due due IN cord-006870-f5w6fw6q 1487 7 to to IN cord-006870-f5w6fw6q 1487 8 small small JJ cord-006870-f5w6fw6q 1487 9 sample sample NN cord-006870-f5w6fw6q 1487 10 size size NN cord-006870-f5w6fw6q 1487 11 in in IN cord-006870-f5w6fw6q 1487 12 our -PRON- PRP$ cord-006870-f5w6fw6q 1487 13 study study NN cord-006870-f5w6fw6q 1487 14 , , , cord-006870-f5w6fw6q 1487 15 further further JJ cord-006870-f5w6fw6q 1487 16 studies study NNS cord-006870-f5w6fw6q 1487 17 with with IN cord-006870-f5w6fw6q 1487 18 prospective prospective JJ cord-006870-f5w6fw6q 1487 19 larger large JJR cord-006870-f5w6fw6q 1487 20 patient patient JJ cord-006870-f5w6fw6q 1487 21 cohorts cohort NNS cord-006870-f5w6fw6q 1487 22 will will MD cord-006870-f5w6fw6q 1487 23 need need VB cord-006870-f5w6fw6q 1487 24 to to TO cord-006870-f5w6fw6q 1487 25 be be VB cord-006870-f5w6fw6q 1487 26 conducted conduct VBN cord-006870-f5w6fw6q 1487 27 . . . cord-006870-f5w6fw6q 1488 1 Novel novel JJ cord-006870-f5w6fw6q 1488 2 Oral oral JJ cord-006870-f5w6fw6q 1488 3 Anticoagulants anticoagulant NNS cord-006870-f5w6fw6q 1488 4 ( ( -LRB- cord-006870-f5w6fw6q 1488 5 NOAC NOAC NNP cord-006870-f5w6fw6q 1488 6 ) ) -RRB- cord-006870-f5w6fw6q 1488 7 are be VBP cord-006870-f5w6fw6q 1488 8 increasingly increasingly RB cord-006870-f5w6fw6q 1488 9 used use VBN cord-006870-f5w6fw6q 1488 10 as as IN cord-006870-f5w6fw6q 1488 11 an an DT cord-006870-f5w6fw6q 1488 12 alternative alternative NN cord-006870-f5w6fw6q 1488 13 to to IN cord-006870-f5w6fw6q 1488 14 vitamin vitamin NN cord-006870-f5w6fw6q 1488 15 - - HYPH cord-006870-f5w6fw6q 1488 16 K k NN cord-006870-f5w6fw6q 1488 17 antagonists antagonist NNS cord-006870-f5w6fw6q 1488 18 ( ( -LRB- cord-006870-f5w6fw6q 1488 19 VKA VKA NNP cord-006870-f5w6fw6q 1488 20 ) ) -RRB- cord-006870-f5w6fw6q 1488 21 such such JJ cord-006870-f5w6fw6q 1488 22 as as IN cord-006870-f5w6fw6q 1488 23 warfarin warfarin NN cord-006870-f5w6fw6q 1488 24 for for IN cord-006870-f5w6fw6q 1488 25 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 1488 26 and and CC cord-006870-f5w6fw6q 1488 27 have have VBP cord-006870-f5w6fw6q 1488 28 shown show VBN cord-006870-f5w6fw6q 1488 29 lower low JJR cord-006870-f5w6fw6q 1488 30 rates rate NNS cord-006870-f5w6fw6q 1488 31 of of IN cord-006870-f5w6fw6q 1488 32 intracranial intracranial JJ cord-006870-f5w6fw6q 1488 33 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1488 34 in in IN cord-006870-f5w6fw6q 1488 35 several several JJ cord-006870-f5w6fw6q 1488 36 randomized randomized JJ cord-006870-f5w6fw6q 1488 37 clinical clinical JJ cord-006870-f5w6fw6q 1488 38 trials trial NNS cord-006870-f5w6fw6q 1488 39 . . . cord-006870-f5w6fw6q 1489 1 It -PRON- PRP cord-006870-f5w6fw6q 1489 2 has have VBZ cord-006870-f5w6fw6q 1489 3 been be VBN cord-006870-f5w6fw6q 1489 4 suggested suggest VBN cord-006870-f5w6fw6q 1489 5 that that IN cord-006870-f5w6fw6q 1489 6 NOAC NOAC NNP cord-006870-f5w6fw6q 1489 7 - - HYPH cord-006870-f5w6fw6q 1489 8 IPHs IPHs NNP cord-006870-f5w6fw6q 1489 9 might may MD cord-006870-f5w6fw6q 1489 10 be be VB cord-006870-f5w6fw6q 1489 11 particularly particularly RB cord-006870-f5w6fw6q 1489 12 dangerous dangerous JJ cord-006870-f5w6fw6q 1489 13 , , , cord-006870-f5w6fw6q 1489 14 yet yet CC cord-006870-f5w6fw6q 1489 15 the the DT cord-006870-f5w6fw6q 1489 16 literature literature NN cord-006870-f5w6fw6q 1489 17 regarding regard VBG cord-006870-f5w6fw6q 1489 18 hematoma hematoma NN cord-006870-f5w6fw6q 1489 19 characteristics characteristic NNS cord-006870-f5w6fw6q 1489 20 and and CC cord-006870-f5w6fw6q 1489 21 outcomes outcome NNS cord-006870-f5w6fw6q 1489 22 between between IN cord-006870-f5w6fw6q 1489 23 NOAC NOAC NNP cord-006870-f5w6fw6q 1489 24 - - HYPH cord-006870-f5w6fw6q 1489 25 IPHs IPHs NNP cord-006870-f5w6fw6q 1489 26 and and CC cord-006870-f5w6fw6q 1489 27 VKA vka NN cord-006870-f5w6fw6q 1489 28 - - HYPH cord-006870-f5w6fw6q 1489 29 IPHs IPHs NNP cord-006870-f5w6fw6q 1489 30 is be VBZ cord-006870-f5w6fw6q 1489 31 inconclusive inconclusive JJ cord-006870-f5w6fw6q 1489 32 . . . cord-006870-f5w6fw6q 1490 1 Given give VBN cord-006870-f5w6fw6q 1490 2 the the DT cord-006870-f5w6fw6q 1490 3 lack lack NN cord-006870-f5w6fw6q 1490 4 of of IN cord-006870-f5w6fw6q 1490 5 standardized standardized JJ cord-006870-f5w6fw6q 1490 6 reversal reversal NN cord-006870-f5w6fw6q 1490 7 strategies strategy NNS cord-006870-f5w6fw6q 1490 8 and and CC cord-006870-f5w6fw6q 1490 9 lack lack NN cord-006870-f5w6fw6q 1490 10 of of IN cord-006870-f5w6fw6q 1490 11 information information NN cord-006870-f5w6fw6q 1490 12 on on IN cord-006870-f5w6fw6q 1490 13 outcomes outcome NNS cord-006870-f5w6fw6q 1490 14 following follow VBG cord-006870-f5w6fw6q 1490 15 NOAC NOAC NNP cord-006870-f5w6fw6q 1490 16 - - HYPH cord-006870-f5w6fw6q 1490 17 associated associate VBN cord-006870-f5w6fw6q 1490 18 IPH IPH NNP cord-006870-f5w6fw6q 1490 19 , , , cord-006870-f5w6fw6q 1490 20 the the DT cord-006870-f5w6fw6q 1490 21 aim aim NN cord-006870-f5w6fw6q 1490 22 of of IN cord-006870-f5w6fw6q 1490 23 this this DT cord-006870-f5w6fw6q 1490 24 meta meta NNP cord-006870-f5w6fw6q 1490 25 - - HYPH cord-006870-f5w6fw6q 1490 26 analysis analysis NN cord-006870-f5w6fw6q 1490 27 was be VBD cord-006870-f5w6fw6q 1490 28 to to TO cord-006870-f5w6fw6q 1490 29 compare compare VB cord-006870-f5w6fw6q 1490 30 1 1 CD cord-006870-f5w6fw6q 1490 31 ) ) -RRB- cord-006870-f5w6fw6q 1490 32 mortality mortality NN cord-006870-f5w6fw6q 1490 33 ; ; : cord-006870-f5w6fw6q 1490 34 2 2 LS cord-006870-f5w6fw6q 1490 35 ) ) -RRB- cord-006870-f5w6fw6q 1490 36 hematoma hematoma NN cord-006870-f5w6fw6q 1490 37 volume volume NN cord-006870-f5w6fw6q 1490 38 , , , cord-006870-f5w6fw6q 1490 39 and and CC cord-006870-f5w6fw6q 1490 40 3 3 LS cord-006870-f5w6fw6q 1490 41 ) ) -RRB- cord-006870-f5w6fw6q 1490 42 risk risk NN cord-006870-f5w6fw6q 1490 43 of of IN cord-006870-f5w6fw6q 1490 44 hematoma hematoma NN cord-006870-f5w6fw6q 1490 45 expansion expansion NN cord-006870-f5w6fw6q 1490 46 in in IN cord-006870-f5w6fw6q 1490 47 patients patient NNS cord-006870-f5w6fw6q 1490 48 who who WP cord-006870-f5w6fw6q 1490 49 developed develop VBD cord-006870-f5w6fw6q 1490 50 an an DT cord-006870-f5w6fw6q 1490 51 IPH IPH NNP cord-006870-f5w6fw6q 1490 52 on on IN cord-006870-f5w6fw6q 1490 53 NOACs noac NNS cord-006870-f5w6fw6q 1490 54 versus versus IN cord-006870-f5w6fw6q 1490 55 VKA VKA NNP cord-006870-f5w6fw6q 1490 56 . . . cord-006870-f5w6fw6q 1491 1 A a DT cord-006870-f5w6fw6q 1491 2 meta meta JJ cord-006870-f5w6fw6q 1491 3 - - HYPH cord-006870-f5w6fw6q 1491 4 analysis analysis NN cord-006870-f5w6fw6q 1491 5 of of IN cord-006870-f5w6fw6q 1491 6 the the DT cord-006870-f5w6fw6q 1491 7 literature literature NN cord-006870-f5w6fw6q 1491 8 through through IN cord-006870-f5w6fw6q 1491 9 December December NNP cord-006870-f5w6fw6q 1491 10 2016 2016 CD cord-006870-f5w6fw6q 1491 11 was be VBD cord-006870-f5w6fw6q 1491 12 conducted conduct VBN cord-006870-f5w6fw6q 1491 13 using use VBG cord-006870-f5w6fw6q 1491 14 PubMed PubMed NNP cord-006870-f5w6fw6q 1491 15 , , , cord-006870-f5w6fw6q 1491 16 EMBASE EMBASE NNP cord-006870-f5w6fw6q 1491 17 and and CC cord-006870-f5w6fw6q 1491 18 Cochrane Cochrane NNP cord-006870-f5w6fw6q 1491 19 databases database NNS cord-006870-f5w6fw6q 1491 20 in in IN cord-006870-f5w6fw6q 1491 21 accordance accordance NN cord-006870-f5w6fw6q 1491 22 with with IN cord-006870-f5w6fw6q 1491 23 PRISMA PRISMA NNP cord-006870-f5w6fw6q 1491 24 guidelines guideline NNS cord-006870-f5w6fw6q 1491 25 . . . cord-006870-f5w6fw6q 1492 1 Pooled pool VBN cord-006870-f5w6fw6q 1492 2 risk risk NN cord-006870-f5w6fw6q 1492 3 ratios ratio NNS cord-006870-f5w6fw6q 1492 4 ( ( -LRB- cord-006870-f5w6fw6q 1492 5 RR RR NNP cord-006870-f5w6fw6q 1492 6 ) ) -RRB- cord-006870-f5w6fw6q 1492 7 were be VBD cord-006870-f5w6fw6q 1492 8 calculated calculate VBN cord-006870-f5w6fw6q 1492 9 for for IN cord-006870-f5w6fw6q 1492 10 mortality mortality NN cord-006870-f5w6fw6q 1492 11 and and CC cord-006870-f5w6fw6q 1492 12 hematoma hematoma NN cord-006870-f5w6fw6q 1492 13 expansion expansion NN cord-006870-f5w6fw6q 1492 14 and and CC cord-006870-f5w6fw6q 1492 15 pooled pool VBN cord-006870-f5w6fw6q 1492 16 mean mean JJ cord-006870-f5w6fw6q 1492 17 difference difference NN cord-006870-f5w6fw6q 1492 18 ( ( -LRB- cord-006870-f5w6fw6q 1492 19 MD MD NNP cord-006870-f5w6fw6q 1492 20 ) ) -RRB- cord-006870-f5w6fw6q 1492 21 was be VBD cord-006870-f5w6fw6q 1492 22 calculated calculate VBN cord-006870-f5w6fw6q 1492 23 for for IN cord-006870-f5w6fw6q 1492 24 hematoma hematoma NN cord-006870-f5w6fw6q 1492 25 volume volume NN cord-006870-f5w6fw6q 1492 26 ( ( -LRB- cord-006870-f5w6fw6q 1492 27 ml ml NN cord-006870-f5w6fw6q 1492 28 ) ) -RRB- cord-006870-f5w6fw6q 1492 29 using use VBG cord-006870-f5w6fw6q 1492 30 random random JJ cord-006870-f5w6fw6q 1492 31 - - HYPH cord-006870-f5w6fw6q 1492 32 effect effect NN cord-006870-f5w6fw6q 1492 33 ( ( -LRB- cord-006870-f5w6fw6q 1492 34 RE re NN cord-006870-f5w6fw6q 1492 35 ) ) -RRB- cord-006870-f5w6fw6q 1492 36 and and CC cord-006870-f5w6fw6q 1492 37 fixed fix VBN cord-006870-f5w6fw6q 1492 38 - - HYPH cord-006870-f5w6fw6q 1492 39 effect effect NN cord-006870-f5w6fw6q 1492 40 ( ( -LRB- cord-006870-f5w6fw6q 1492 41 FE FE NNP cord-006870-f5w6fw6q 1492 42 ) ) -RRB- cord-006870-f5w6fw6q 1492 43 models model NNS cord-006870-f5w6fw6q 1492 44 . . . cord-006870-f5w6fw6q 1493 1 NOAC NOAC NNP cord-006870-f5w6fw6q 1493 2 - - HYPH cord-006870-f5w6fw6q 1493 3 IPH IPH NNP cord-006870-f5w6fw6q 1493 4 was be VBD cord-006870-f5w6fw6q 1493 5 not not RB cord-006870-f5w6fw6q 1493 6 associated associate VBN cord-006870-f5w6fw6q 1493 7 with with IN cord-006870-f5w6fw6q 1493 8 increased increase VBN cord-006870-f5w6fw6q 1493 9 mortality mortality NN cord-006870-f5w6fw6q 1493 10 ( ( -LRB- cord-006870-f5w6fw6q 1493 11 RE RE NNP cord-006870-f5w6fw6q 1493 12 and and CC cord-006870-f5w6fw6q 1493 13 FE FE NNP cord-006870-f5w6fw6q 1493 14 : : : cord-006870-f5w6fw6q 1493 15 RR rr NN cord-006870-f5w6fw6q 1493 16 : : : cord-006870-f5w6fw6q 1493 17 1.07 1.07 CD cord-006870-f5w6fw6q 1493 18 ; ; : cord-006870-f5w6fw6q 1493 19 95%-CI 95%-ci CD cord-006870-f5w6fw6q 1493 20 : : : cord-006870-f5w6fw6q 1493 21 0.89;1.28 0.89;1.28 CD cord-006870-f5w6fw6q 1493 22 , , , cord-006870-f5w6fw6q 1493 23 I2=0.00 I2=0.00 NNP cord-006870-f5w6fw6q 1493 24 % % NN cord-006870-f5w6fw6q 1493 25 , , , cord-006870-f5w6fw6q 1493 26 p p NN cord-006870-f5w6fw6q 1493 27 - - : cord-006870-f5w6fw6q 1493 28 heterogeneity=0.29 heterogeneity=0.29 NNP cord-006870-f5w6fw6q 1493 29 ; ; : cord-006870-f5w6fw6q 1493 30 7 7 CD cord-006870-f5w6fw6q 1493 31 studies study NNS cord-006870-f5w6fw6q 1493 32 ) ) -RRB- cord-006870-f5w6fw6q 1493 33 and and CC cord-006870-f5w6fw6q 1493 34 hematoma hematoma NN cord-006870-f5w6fw6q 1493 35 expansion expansion NN cord-006870-f5w6fw6q 1493 36 ( ( -LRB- cord-006870-f5w6fw6q 1493 37 RE RE NNP cord-006870-f5w6fw6q 1493 38 and and CC cord-006870-f5w6fw6q 1493 39 FE FE NNP cord-006870-f5w6fw6q 1493 40 : : : cord-006870-f5w6fw6q 1493 41 RR rr NN cord-006870-f5w6fw6q 1493 42 : : : cord-006870-f5w6fw6q 1493 43 0.97 0.97 CD cord-006870-f5w6fw6q 1493 44 ; ; : cord-006870-f5w6fw6q 1493 45 95%-CI 95%-ci CD cord-006870-f5w6fw6q 1493 46 : : SYM cord-006870-f5w6fw6q 1493 47 0.77;1.21 0.77;1.21 CD cord-006870-f5w6fw6q 1493 48 , , , cord-006870-f5w6fw6q 1493 49 I2=0.00 I2=0.00 NNP cord-006870-f5w6fw6q 1493 50 % % NN cord-006870-f5w6fw6q 1493 51 , , , cord-006870-f5w6fw6q 1493 52 p p NN cord-006870-f5w6fw6q 1493 53 - - : cord-006870-f5w6fw6q 1493 54 heterogeneity=0.48 heterogeneity=0.48 NNP cord-006870-f5w6fw6q 1493 55 ; ; : cord-006870-f5w6fw6q 1493 56 4 4 CD cord-006870-f5w6fw6q 1493 57 studies study NNS cord-006870-f5w6fw6q 1493 58 ) ) -RRB- cord-006870-f5w6fw6q 1493 59 compared compare VBN cord-006870-f5w6fw6q 1493 60 to to IN cord-006870-f5w6fw6q 1493 61 VKA VKA NNP cord-006870-f5w6fw6q 1493 62 - - HYPH cord-006870-f5w6fw6q 1493 63 IPH IPH NNP cord-006870-f5w6fw6q 1493 64 . . . cord-006870-f5w6fw6q 1494 1 The the DT cord-006870-f5w6fw6q 1494 2 hematoma hematoma NN cord-006870-f5w6fw6q 1494 3 volume volume NN cord-006870-f5w6fw6q 1494 4 of of IN cord-006870-f5w6fw6q 1494 5 NOAC NOAC NNP cord-006870-f5w6fw6q 1494 6 - - HYPH cord-006870-f5w6fw6q 1494 7 IPH IPH NNP cord-006870-f5w6fw6q 1494 8 was be VBD cord-006870-f5w6fw6q 1494 9 smaller small JJR cord-006870-f5w6fw6q 1494 10 than than IN cord-006870-f5w6fw6q 1494 11 VKA VKA NNP cord-006870-f5w6fw6q 1494 12 - - HYPH cord-006870-f5w6fw6q 1494 13 IPH IPH NNP cord-006870-f5w6fw6q 1495 1 ( ( -LRB- cord-006870-f5w6fw6q 1495 2 RE RE NNP cord-006870-f5w6fw6q 1495 3 : : : cord-006870-f5w6fw6q 1495 4 MD MD NNP cord-006870-f5w6fw6q 1495 5 : : : cord-006870-f5w6fw6q 1495 6 -8.83ml -8.83ml : cord-006870-f5w6fw6q 1495 7 ; ; : cord-006870-f5w6fw6q 1495 8 95%-CI 95%-ci CD cord-006870-f5w6fw6q 1495 9 : : : cord-006870-f5w6fw6q 1496 1 -17.00 -17.00 LS cord-006870-f5w6fw6q 1496 2 ; ; : cord-006870-f5w6fw6q 1497 1 -0.67 -0.67 NFP cord-006870-f5w6fw6q 1497 2 , , , cord-006870-f5w6fw6q 1497 3 FE FE NNP cord-006870-f5w6fw6q 1497 4 : : : cord-006870-f5w6fw6q 1497 5 MD MD NNP cord-006870-f5w6fw6q 1497 6 : : : cord-006870-f5w6fw6q 1497 7 -6.48ml -6.48ml : cord-006870-f5w6fw6q 1497 8 ; ; : cord-006870-f5w6fw6q 1498 1 95%-CI 95%-ci CD cord-006870-f5w6fw6q 1498 2 : : : cord-006870-f5w6fw6q 1498 3 -9.85 -9.85 : cord-006870-f5w6fw6q 1498 4 ; ; : cord-006870-f5w6fw6q 1498 5 -3.10 -3.10 CD cord-006870-f5w6fw6q 1498 6 ; ; : cord-006870-f5w6fw6q 1498 7 5 5 CD cord-006870-f5w6fw6q 1498 8 studies study NNS cord-006870-f5w6fw6q 1498 9 ) ) -RRB- cord-006870-f5w6fw6q 1498 10 , , , cord-006870-f5w6fw6q 1498 11 but but CC cord-006870-f5w6fw6q 1498 12 with with IN cord-006870-f5w6fw6q 1498 13 considerable considerable JJ cord-006870-f5w6fw6q 1498 14 heterogeneity heterogeneity NN cord-006870-f5w6fw6q 1498 15 that that WDT cord-006870-f5w6fw6q 1498 16 could could MD cord-006870-f5w6fw6q 1498 17 not not RB cord-006870-f5w6fw6q 1498 18 be be VB cord-006870-f5w6fw6q 1498 19 alleviated alleviate VBN cord-006870-f5w6fw6q 1498 20 ( ( -LRB- cord-006870-f5w6fw6q 1498 21 I2=79.1 I2=79.1 NNP cord-006870-f5w6fw6q 1498 22 % % NN cord-006870-f5w6fw6q 1498 23 , , , cord-006870-f5w6fw6q 1498 24 p p NN cord-006870-f5w6fw6q 1498 25 - - HYPH cord-006870-f5w6fw6q 1498 26 heterogeneity0.05 heterogeneity0.05 NNP cord-006870-f5w6fw6q 1498 27 ) ) -RRB- cord-006870-f5w6fw6q 1498 28 . . . cord-006870-f5w6fw6q 1499 1 NOAC NOAC NNP cord-006870-f5w6fw6q 1499 2 - - HYPH cord-006870-f5w6fw6q 1499 3 IPH IPH NNP cord-006870-f5w6fw6q 1499 4 was be VBD cord-006870-f5w6fw6q 1499 5 not not RB cord-006870-f5w6fw6q 1499 6 associated associate VBN cord-006870-f5w6fw6q 1499 7 with with IN cord-006870-f5w6fw6q 1499 8 increased increase VBN cord-006870-f5w6fw6q 1499 9 mortality mortality NN cord-006870-f5w6fw6q 1499 10 or or CC cord-006870-f5w6fw6q 1499 11 hematoma hematoma NN cord-006870-f5w6fw6q 1499 12 expansion expansion NN cord-006870-f5w6fw6q 1499 13 compared compare VBN cord-006870-f5w6fw6q 1499 14 to to IN cord-006870-f5w6fw6q 1499 15 VKA VKA NNP cord-006870-f5w6fw6q 1499 16 - - HYPH cord-006870-f5w6fw6q 1499 17 IPH IPH NNP cord-006870-f5w6fw6q 1499 18 and and CC cord-006870-f5w6fw6q 1499 19 may may MD cord-006870-f5w6fw6q 1499 20 be be VB cord-006870-f5w6fw6q 1499 21 associated associate VBN cord-006870-f5w6fw6q 1499 22 with with IN cord-006870-f5w6fw6q 1499 23 a a DT cord-006870-f5w6fw6q 1499 24 smaller small JJR cord-006870-f5w6fw6q 1499 25 hematoma hematoma NN cord-006870-f5w6fw6q 1499 26 volume volume NN cord-006870-f5w6fw6q 1499 27 . . . cord-006870-f5w6fw6q 1500 1 Controversy controversy NN cord-006870-f5w6fw6q 1500 2 exists exist VBZ cord-006870-f5w6fw6q 1500 3 regarding regard VBG cord-006870-f5w6fw6q 1500 4 blood blood NN cord-006870-f5w6fw6q 1500 5 pressure pressure NN cord-006870-f5w6fw6q 1500 6 ( ( -LRB- cord-006870-f5w6fw6q 1500 7 BP BP NNP cord-006870-f5w6fw6q 1500 8 ) ) -RRB- cord-006870-f5w6fw6q 1500 9 reduction reduction NN cord-006870-f5w6fw6q 1500 10 and and CC cord-006870-f5w6fw6q 1500 11 perihematomal perihematomal NNP cord-006870-f5w6fw6q 1500 12 ischemia ischemia NN cord-006870-f5w6fw6q 1500 13 ( ( -LRB- cord-006870-f5w6fw6q 1500 14 PHI PHI NNP cord-006870-f5w6fw6q 1500 15 ) ) -RRB- cord-006870-f5w6fw6q 1500 16 . . . cord-006870-f5w6fw6q 1501 1 We -PRON- PRP cord-006870-f5w6fw6q 1501 2 investigated investigate VBD cord-006870-f5w6fw6q 1501 3 the the DT cord-006870-f5w6fw6q 1501 4 association association NN cord-006870-f5w6fw6q 1501 5 of of IN cord-006870-f5w6fw6q 1501 6 acute acute JJ cord-006870-f5w6fw6q 1501 7 BP BP NNP cord-006870-f5w6fw6q 1501 8 reduction reduction NN cord-006870-f5w6fw6q 1501 9 and and CC cord-006870-f5w6fw6q 1501 10 presence presence NN cord-006870-f5w6fw6q 1501 11 of of IN cord-006870-f5w6fw6q 1501 12 qualitative qualitative JJ cord-006870-f5w6fw6q 1501 13 and and CC cord-006870-f5w6fw6q 1501 14 quantitative quantitative JJ cord-006870-f5w6fw6q 1501 15 PHI phi NN cord-006870-f5w6fw6q 1501 16 in in IN cord-006870-f5w6fw6q 1501 17 a a DT cord-006870-f5w6fw6q 1501 18 large large JJ cord-006870-f5w6fw6q 1501 19 prospective prospective JJ cord-006870-f5w6fw6q 1501 20 cohort cohort NN cord-006870-f5w6fw6q 1501 21 of of IN cord-006870-f5w6fw6q 1501 22 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1501 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1501 24 ( ( -LRB- cord-006870-f5w6fw6q 1501 25 ICH ICH NNP cord-006870-f5w6fw6q 1501 26 ) ) -RRB- cord-006870-f5w6fw6q 1501 27 . . . cord-006870-f5w6fw6q 1502 1 Consecutive consecutive JJ cord-006870-f5w6fw6q 1502 2 patients patient NNS cord-006870-f5w6fw6q 1502 3 from from IN cord-006870-f5w6fw6q 1502 4 the the DT cord-006870-f5w6fw6q 1502 5 prospective prospective JJ cord-006870-f5w6fw6q 1502 6 NIH NIH NNP cord-006870-f5w6fw6q 1502 7 funded fund VBN cord-006870-f5w6fw6q 1502 8 DASH1 DASH1 NNP cord-006870-f5w6fw6q 1502 9 study study NN cord-006870-f5w6fw6q 1502 10 ( ( -LRB- cord-006870-f5w6fw6q 1502 11 > > NFP cord-006870-f5w6fw6q 1502 12 18 18 CD cord-006870-f5w6fw6q 1502 13 years year NNS cord-006870-f5w6fw6q 1502 14 , , , cord-006870-f5w6fw6q 1502 15 primary primary JJ cord-006870-f5w6fw6q 1502 16 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1502 17 ICH ICH NNP cord-006870-f5w6fw6q 1502 18 ) ) -RRB- cord-006870-f5w6fw6q 1502 19 were be VBD cord-006870-f5w6fw6q 1502 20 included include VBN cord-006870-f5w6fw6q 1502 21 . . . cord-006870-f5w6fw6q 1503 1 PHE PHE NNP cord-006870-f5w6fw6q 1503 2 volume volume NN cord-006870-f5w6fw6q 1503 3 was be VBD cord-006870-f5w6fw6q 1503 4 outlined outline VBN cord-006870-f5w6fw6q 1503 5 on on IN cord-006870-f5w6fw6q 1503 6 T2 T2 NNP cord-006870-f5w6fw6q 1503 7 / / SYM cord-006870-f5w6fw6q 1503 8 FLAIR FLAIR NNP cord-006870-f5w6fw6q 1503 9 and and CC cord-006870-f5w6fw6q 1503 10 ICH ICH NNP cord-006870-f5w6fw6q 1503 11 volume volume NN cord-006870-f5w6fw6q 1503 12 on on IN cord-006870-f5w6fw6q 1503 13 GRE GRE NNP cord-006870-f5w6fw6q 1503 14 ; ; : cord-006870-f5w6fw6q 1503 15 these these DT cord-006870-f5w6fw6q 1503 16 and and CC cord-006870-f5w6fw6q 1503 17 ADC ADC NNP cord-006870-f5w6fw6q 1503 18 were be VBD cord-006870-f5w6fw6q 1503 19 co co JJ cord-006870-f5w6fw6q 1503 20 - - VBN cord-006870-f5w6fw6q 1503 21 registered register VBN cord-006870-f5w6fw6q 1503 22 . . . cord-006870-f5w6fw6q 1504 1 Tissue tissue NN cord-006870-f5w6fw6q 1504 2 characteristics characteristic NNS cord-006870-f5w6fw6q 1504 3 was be VBD cord-006870-f5w6fw6q 1504 4 defined define VBN cord-006870-f5w6fw6q 1504 5 as as IN cord-006870-f5w6fw6q 1504 6 : : : cord-006870-f5w6fw6q 1505 1 CE CE NNP cord-006870-f5w6fw6q 1505 2 = = SYM cord-006870-f5w6fw6q 1505 3 ADC ADC NNP cord-006870-f5w6fw6q 1505 4 1200 1200 CD cord-006870-f5w6fw6q 1505 5 x x SYM cord-006870-f5w6fw6q 1505 6 10 10 CD cord-006870-f5w6fw6q 1505 7 - - SYM cord-006870-f5w6fw6q 1505 8 6 6 CD cord-006870-f5w6fw6q 1505 9 mm2 mm2 NNPS cord-006870-f5w6fw6q 1505 10 / / SYM cord-006870-f5w6fw6q 1505 11 sec sec NNP cord-006870-f5w6fw6q 1505 12 . . . cord-006870-f5w6fw6q 1506 1 The the DT cord-006870-f5w6fw6q 1506 2 association association NN cord-006870-f5w6fw6q 1506 3 of of IN cord-006870-f5w6fw6q 1506 4 clinical clinical JJ cord-006870-f5w6fw6q 1506 5 , , , cord-006870-f5w6fw6q 1506 6 radiographic radiographic JJ cord-006870-f5w6fw6q 1506 7 factors factor NNS cord-006870-f5w6fw6q 1506 8 and and CC cord-006870-f5w6fw6q 1506 9 BP BP NNP cord-006870-f5w6fw6q 1506 10 at at IN cord-006870-f5w6fw6q 1506 11 baseline baseline NN cord-006870-f5w6fw6q 1506 12 and and CC cord-006870-f5w6fw6q 1506 13 24 24 CD cord-006870-f5w6fw6q 1506 14 hours hour NNS cord-006870-f5w6fw6q 1506 15 with with IN cord-006870-f5w6fw6q 1506 16 qualitative qualitative JJ cord-006870-f5w6fw6q 1506 17 perihematomal perihematomal NNS cord-006870-f5w6fw6q 1506 18 and/or and/or CC cord-006870-f5w6fw6q 1506 19 remote remote JJ cord-006870-f5w6fw6q 1506 20 ischemia ischemia NN cord-006870-f5w6fw6q 1506 21 ( ( -LRB- cord-006870-f5w6fw6q 1506 22 i.e. i.e. FW cord-006870-f5w6fw6q 1506 23 DWI DWI NNP cord-006870-f5w6fw6q 1506 24 bright bright JJ cord-006870-f5w6fw6q 1506 25 ADC ADC NNP cord-006870-f5w6fw6q 1506 26 dark dark NN cord-006870-f5w6fw6q 1506 27 ) ) -RRB- cord-006870-f5w6fw6q 1506 28 and and CC cord-006870-f5w6fw6q 1506 29 quantitative quantitative JJ cord-006870-f5w6fw6q 1506 30 CE CE NNP cord-006870-f5w6fw6q 1506 31 on on IN cord-006870-f5w6fw6q 1506 32 ADC ADC NNP cord-006870-f5w6fw6q 1506 33 were be VBD cord-006870-f5w6fw6q 1506 34 determined determine VBN cord-006870-f5w6fw6q 1506 35 . . . cord-006870-f5w6fw6q 1507 1 164 164 CD cord-006870-f5w6fw6q 1507 2 patients patient NNS cord-006870-f5w6fw6q 1507 3 ( ( -LRB- cord-006870-f5w6fw6q 1507 4 50 50 CD cord-006870-f5w6fw6q 1507 5 % % NN cord-006870-f5w6fw6q 1507 6 female female NN cord-006870-f5w6fw6q 1507 7 ) ) -RRB- cord-006870-f5w6fw6q 1507 8 with with IN cord-006870-f5w6fw6q 1507 9 mean mean JJ cord-006870-f5w6fw6q 1507 10 age age NN cord-006870-f5w6fw6q 1507 11 64 64 CD cord-006870-f5w6fw6q 1507 12 ± ± NNP cord-006870-f5w6fw6q 1507 13 15 15 CD cord-006870-f5w6fw6q 1507 14 , , , cord-006870-f5w6fw6q 1507 15 and and CC cord-006870-f5w6fw6q 1507 16 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1507 17 8 8 CD cord-006870-f5w6fw6q 1507 18 ( ( -LRB- cord-006870-f5w6fw6q 1507 19 IQR IQR NNP cord-006870-f5w6fw6q 1507 20 3 3 CD cord-006870-f5w6fw6q 1507 21 , , , cord-006870-f5w6fw6q 1507 22 17 17 CD cord-006870-f5w6fw6q 1507 23 ) ) -RRB- cord-006870-f5w6fw6q 1507 24 were be VBD cord-006870-f5w6fw6q 1507 25 included include VBN cord-006870-f5w6fw6q 1507 26 . . . cord-006870-f5w6fw6q 1508 1 MRI MRI NNP cord-006870-f5w6fw6q 1508 2 time time NN cord-006870-f5w6fw6q 1508 3 was be VBD cord-006870-f5w6fw6q 1508 4 34.6 34.6 CD cord-006870-f5w6fw6q 1508 5 hours hour NNS cord-006870-f5w6fw6q 1508 6 ( ( -LRB- cord-006870-f5w6fw6q 1508 7 IQR IQR NNP cord-006870-f5w6fw6q 1508 8 21 21 CD cord-006870-f5w6fw6q 1508 9 , , , cord-006870-f5w6fw6q 1508 10 60 60 CD cord-006870-f5w6fw6q 1508 11 ) ) -RRB- cord-006870-f5w6fw6q 1508 12 . . . cord-006870-f5w6fw6q 1509 1 37 37 CD cord-006870-f5w6fw6q 1509 2 % % NN cord-006870-f5w6fw6q 1509 3 had have VBD cord-006870-f5w6fw6q 1509 4 lobar lobar NN cord-006870-f5w6fw6q 1509 5 ICH ICH NNP cord-006870-f5w6fw6q 1509 6 . . . cord-006870-f5w6fw6q 1510 1 ICH ICH NNP cord-006870-f5w6fw6q 1510 2 volume volume NN cord-006870-f5w6fw6q 1510 3 was be VBD cord-006870-f5w6fw6q 1510 4 12 12 CD cord-006870-f5w6fw6q 1510 5 cc cc NNS cord-006870-f5w6fw6q 1510 6 ( ( -LRB- cord-006870-f5w6fw6q 1510 7 IQR IQR NNP cord-006870-f5w6fw6q 1510 8 5 5 CD cord-006870-f5w6fw6q 1510 9 , , , cord-006870-f5w6fw6q 1510 10 33 33 CD cord-006870-f5w6fw6q 1510 11 ) ) -RRB- cord-006870-f5w6fw6q 1510 12 . . . cord-006870-f5w6fw6q 1511 1 44 44 CD cord-006870-f5w6fw6q 1511 2 % % NN cord-006870-f5w6fw6q 1511 3 had have VBD cord-006870-f5w6fw6q 1511 4 perihematomal perihematomal NNS cord-006870-f5w6fw6q 1511 5 ( ( -LRB- cord-006870-f5w6fw6q 1511 6 33 33 CD cord-006870-f5w6fw6q 1511 7 % % NN cord-006870-f5w6fw6q 1511 8 ) ) -RRB- cord-006870-f5w6fw6q 1511 9 or or CC cord-006870-f5w6fw6q 1511 10 remote remote JJ cord-006870-f5w6fw6q 1511 11 ischemia ischemia NN cord-006870-f5w6fw6q 1511 12 ( ( -LRB- cord-006870-f5w6fw6q 1511 13 21 21 CD cord-006870-f5w6fw6q 1511 14 % % NN cord-006870-f5w6fw6q 1511 15 ) ) -RRB- cord-006870-f5w6fw6q 1511 16 . . . cord-006870-f5w6fw6q 1512 1 99 99 CD cord-006870-f5w6fw6q 1512 2 % % NN cord-006870-f5w6fw6q 1512 3 of of IN cord-006870-f5w6fw6q 1512 4 patients patient NNS cord-006870-f5w6fw6q 1512 5 had have VBD cord-006870-f5w6fw6q 1512 6 areas area NNS cord-006870-f5w6fw6q 1512 7 of of IN cord-006870-f5w6fw6q 1512 8 perihematomal perihematomal NNP cord-006870-f5w6fw6q 1512 9 ADC ADC NNP cord-006870-f5w6fw6q 1512 10 1 1 CD cord-006870-f5w6fw6q 1512 11 cc cc CD cord-006870-f5w6fw6q 1512 12 ) ) -RRB- cord-006870-f5w6fw6q 1512 13 was be VBD cord-006870-f5w6fw6q 1512 14 associated associate VBN cord-006870-f5w6fw6q 1512 15 with with IN cord-006870-f5w6fw6q 1512 16 higher high JJR cord-006870-f5w6fw6q 1512 17 absolute absolute JJ cord-006870-f5w6fw6q 1512 18 ( ( -LRB- cord-006870-f5w6fw6q 1512 19 52±30 52±30 JJ cord-006870-f5w6fw6q 1512 20 mm mm NN cord-006870-f5w6fw6q 1512 21 Hg hg NN cord-006870-f5w6fw6q 1512 22 , , , cord-006870-f5w6fw6q 1512 23 p=0.05 p=0.05 JJ cord-006870-f5w6fw6q 1512 24 ) ) -RRB- cord-006870-f5w6fw6q 1512 25 and and CC cord-006870-f5w6fw6q 1512 26 relative relative JJ cord-006870-f5w6fw6q 1512 27 ( ( -LRB- cord-006870-f5w6fw6q 1512 28 38 38 CD cord-006870-f5w6fw6q 1512 29 % % NN cord-006870-f5w6fw6q 1512 30 ± ± NNP cord-006870-f5w6fw6q 1512 31 16 16 CD cord-006870-f5w6fw6q 1512 32 % % NN cord-006870-f5w6fw6q 1512 33 vs vs IN cord-006870-f5w6fw6q 1512 34 33 33 CD cord-006870-f5w6fw6q 1512 35 % % NN cord-006870-f5w6fw6q 1512 36 ± ± NNP cord-006870-f5w6fw6q 1512 37 15 15 CD cord-006870-f5w6fw6q 1512 38 % % NN cord-006870-f5w6fw6q 1512 39 , , , cord-006870-f5w6fw6q 1512 40 p=0.058 p=0.058 NNP cord-006870-f5w6fw6q 1512 41 ) ) -RRB- cord-006870-f5w6fw6q 1513 1 MAP MAP NNP cord-006870-f5w6fw6q 1513 2 reduction reduction NN cord-006870-f5w6fw6q 1513 3 , , , cord-006870-f5w6fw6q 1513 4 younger young JJR cord-006870-f5w6fw6q 1513 5 age age NN cord-006870-f5w6fw6q 1513 6 ( ( -LRB- cord-006870-f5w6fw6q 1513 7 p=0.03 p=0.03 NN cord-006870-f5w6fw6q 1513 8 ) ) -RRB- cord-006870-f5w6fw6q 1514 1 , , , cord-006870-f5w6fw6q 1514 2 h h NNP cord-006870-f5w6fw6q 1514 3 / / SYM cord-006870-f5w6fw6q 1514 4 o o NN cord-006870-f5w6fw6q 1514 5 TIA TIA NNP cord-006870-f5w6fw6q 1514 6 / / SYM cord-006870-f5w6fw6q 1514 7 stroke stroke NN cord-006870-f5w6fw6q 1514 8 ( ( -LRB- cord-006870-f5w6fw6q 1514 9 p=0.04 p=0.04 NNP cord-006870-f5w6fw6q 1514 10 ) ) -RRB- cord-006870-f5w6fw6q 1514 11 and and CC cord-006870-f5w6fw6q 1514 12 larger large JJR cord-006870-f5w6fw6q 1514 13 ICH ICH NNP cord-006870-f5w6fw6q 1514 14 volumes volume NNS cord-006870-f5w6fw6q 1514 15 ( ( -LRB- cord-006870-f5w6fw6q 1514 16 32 32 CD cord-006870-f5w6fw6q 1514 17 vs vs IN cord-006870-f5w6fw6q 1514 18 7 7 CD cord-006870-f5w6fw6q 1514 19 cc cc NN cord-006870-f5w6fw6q 1514 20 ) ) -RRB- cord-006870-f5w6fw6q 1514 21 ( ( -LRB- cord-006870-f5w6fw6q 1514 22 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1514 23 ) ) -RRB- cord-006870-f5w6fw6q 1514 24 . . . cord-006870-f5w6fw6q 1515 1 In in IN cord-006870-f5w6fw6q 1515 2 multivariate multivariate JJ cord-006870-f5w6fw6q 1515 3 analysis analysis NN cord-006870-f5w6fw6q 1515 4 , , , cord-006870-f5w6fw6q 1515 5 MAP MAP NNP cord-006870-f5w6fw6q 1515 6 reduction reduction NN cord-006870-f5w6fw6q 1515 7 was be VBD cord-006870-f5w6fw6q 1515 8 not not RB cord-006870-f5w6fw6q 1515 9 significantly significantly RB cord-006870-f5w6fw6q 1515 10 associated associate VBN cord-006870-f5w6fw6q 1515 11 with with IN cord-006870-f5w6fw6q 1515 12 CE CE NNP cord-006870-f5w6fw6q 1515 13 whereas whereas IN cord-006870-f5w6fw6q 1515 14 ICH ICH NNP cord-006870-f5w6fw6q 1515 15 volume volume NN cord-006870-f5w6fw6q 1515 16 was be VBD cord-006870-f5w6fw6q 1515 17 ( ( -LRB- cord-006870-f5w6fw6q 1515 18 p=0.00 p=0.00 NNP cord-006870-f5w6fw6q 1515 19 ) ) -RRB- cord-006870-f5w6fw6q 1515 20 . . . cord-006870-f5w6fw6q 1516 1 Perihematomal Perihematomal NNP cord-006870-f5w6fw6q 1516 2 and and CC cord-006870-f5w6fw6q 1516 3 remote remote JJ cord-006870-f5w6fw6q 1516 4 ischemia ischemia NN cord-006870-f5w6fw6q 1516 5 is be VBZ cord-006870-f5w6fw6q 1516 6 frequently frequently RB cord-006870-f5w6fw6q 1516 7 seen see VBN cord-006870-f5w6fw6q 1516 8 after after IN cord-006870-f5w6fw6q 1516 9 ICH ICH NNP cord-006870-f5w6fw6q 1516 10 , , , cord-006870-f5w6fw6q 1516 11 but but CC cord-006870-f5w6fw6q 1516 12 the the DT cord-006870-f5w6fw6q 1516 13 severity severity NN cord-006870-f5w6fw6q 1516 14 of of IN cord-006870-f5w6fw6q 1516 15 PHI PHI NNP cord-006870-f5w6fw6q 1516 16 is be VBZ cord-006870-f5w6fw6q 1516 17 small small JJ cord-006870-f5w6fw6q 1516 18 and and CC cord-006870-f5w6fw6q 1516 19 of of IN cord-006870-f5w6fw6q 1516 20 unclear unclear JJ cord-006870-f5w6fw6q 1516 21 significance significance NN cord-006870-f5w6fw6q 1516 22 . . . cord-006870-f5w6fw6q 1517 1 BP BP NNP cord-006870-f5w6fw6q 1517 2 reduction reduction NN cord-006870-f5w6fw6q 1517 3 may may MD cord-006870-f5w6fw6q 1517 4 be be VB cord-006870-f5w6fw6q 1517 5 associated associate VBN cord-006870-f5w6fw6q 1517 6 with with IN cord-006870-f5w6fw6q 1517 7 PHI phi NN cord-006870-f5w6fw6q 1517 8 but but CC cord-006870-f5w6fw6q 1517 9 this this DT cord-006870-f5w6fw6q 1517 10 was be VBD cord-006870-f5w6fw6q 1517 11 not not RB cord-006870-f5w6fw6q 1517 12 an an DT cord-006870-f5w6fw6q 1517 13 independent independent JJ cord-006870-f5w6fw6q 1517 14 predictor predictor NN cord-006870-f5w6fw6q 1517 15 . . . cord-006870-f5w6fw6q 1518 1 Introduction introduction NN cord-006870-f5w6fw6q 1518 2 : : : cord-006870-f5w6fw6q 1519 1 Patients patient NNS cord-006870-f5w6fw6q 1519 2 with with IN cord-006870-f5w6fw6q 1519 3 Left Left NNP cord-006870-f5w6fw6q 1519 4 Ventricular Ventricular NNP cord-006870-f5w6fw6q 1519 5 Assist Assist NNP cord-006870-f5w6fw6q 1519 6 Devices Devices NNPS cord-006870-f5w6fw6q 1519 7 ( ( -LRB- cord-006870-f5w6fw6q 1519 8 LVADs LVADs NNP cord-006870-f5w6fw6q 1519 9 ) ) -RRB- cord-006870-f5w6fw6q 1519 10 receive receive VBP cord-006870-f5w6fw6q 1519 11 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 1519 12 and and CC cord-006870-f5w6fw6q 1519 13 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 1519 14 therapy therapy NN cord-006870-f5w6fw6q 1519 15 to to TO cord-006870-f5w6fw6q 1519 16 prevent prevent VB cord-006870-f5w6fw6q 1519 17 pump pump NN cord-006870-f5w6fw6q 1519 18 thrombosis thrombosis NN cord-006870-f5w6fw6q 1519 19 . . . cord-006870-f5w6fw6q 1520 1 Consequently consequently RB cord-006870-f5w6fw6q 1520 2 , , , cord-006870-f5w6fw6q 1520 3 neurological neurological JJ cord-006870-f5w6fw6q 1520 4 events event NNS cord-006870-f5w6fw6q 1520 5 including include VBG cord-006870-f5w6fw6q 1520 6 intracranial intracranial JJ cord-006870-f5w6fw6q 1520 7 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1520 8 ( ( -LRB- cord-006870-f5w6fw6q 1520 9 ICH ICH NNP cord-006870-f5w6fw6q 1520 10 ) ) -RRB- cord-006870-f5w6fw6q 1520 11 are be VBP cord-006870-f5w6fw6q 1520 12 one one CD cord-006870-f5w6fw6q 1520 13 of of IN cord-006870-f5w6fw6q 1520 14 the the DT cord-006870-f5w6fw6q 1520 15 most most RBS cord-006870-f5w6fw6q 1520 16 feared fear VBN cord-006870-f5w6fw6q 1520 17 causes cause NNS cord-006870-f5w6fw6q 1520 18 of of IN cord-006870-f5w6fw6q 1520 19 morbidity morbidity NN cord-006870-f5w6fw6q 1520 20 and and CC cord-006870-f5w6fw6q 1520 21 mortality mortality NN cord-006870-f5w6fw6q 1520 22 in in IN cord-006870-f5w6fw6q 1520 23 these these DT cord-006870-f5w6fw6q 1520 24 patients patient NNS cord-006870-f5w6fw6q 1520 25 . . . cord-006870-f5w6fw6q 1521 1 There there EX cord-006870-f5w6fw6q 1521 2 is be VBZ cord-006870-f5w6fw6q 1521 3 little little JJ cord-006870-f5w6fw6q 1521 4 evidence evidence NN cord-006870-f5w6fw6q 1521 5 to to TO cord-006870-f5w6fw6q 1521 6 guide guide VB cord-006870-f5w6fw6q 1521 7 initiation initiation NN cord-006870-f5w6fw6q 1521 8 of of IN cord-006870-f5w6fw6q 1521 9 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 1521 10 after after IN cord-006870-f5w6fw6q 1521 11 such such JJ cord-006870-f5w6fw6q 1521 12 ICH ICH NNP cord-006870-f5w6fw6q 1521 13 events event NNS cord-006870-f5w6fw6q 1521 14 . . . cord-006870-f5w6fw6q 1522 1 Methods method NNS cord-006870-f5w6fw6q 1522 2 : : : cord-006870-f5w6fw6q 1522 3 This this DT cord-006870-f5w6fw6q 1522 4 is be VBZ cord-006870-f5w6fw6q 1522 5 a a DT cord-006870-f5w6fw6q 1522 6 retrospective retrospective JJ cord-006870-f5w6fw6q 1522 7 , , , cord-006870-f5w6fw6q 1522 8 single single JJ cord-006870-f5w6fw6q 1522 9 academic academic JJ cord-006870-f5w6fw6q 1522 10 center center NN cord-006870-f5w6fw6q 1522 11 analysis analysis NN cord-006870-f5w6fw6q 1522 12 of of IN cord-006870-f5w6fw6q 1522 13 LVAD LVAD NNP cord-006870-f5w6fw6q 1522 14 patients patient NNS cord-006870-f5w6fw6q 1522 15 from from IN cord-006870-f5w6fw6q 1522 16 2014 2014 CD cord-006870-f5w6fw6q 1522 17 - - SYM cord-006870-f5w6fw6q 1522 18 2017 2017 CD cord-006870-f5w6fw6q 1522 19 . . . cord-006870-f5w6fw6q 1523 1 The the DT cord-006870-f5w6fw6q 1523 2 electronic electronic JJ cord-006870-f5w6fw6q 1523 3 medical medical JJ cord-006870-f5w6fw6q 1523 4 record record NN cord-006870-f5w6fw6q 1523 5 was be VBD cord-006870-f5w6fw6q 1523 6 reviewed review VBN cord-006870-f5w6fw6q 1523 7 after after IN cord-006870-f5w6fw6q 1523 8 IRB IRB NNP cord-006870-f5w6fw6q 1523 9 approval approval NN cord-006870-f5w6fw6q 1523 10 for for IN cord-006870-f5w6fw6q 1523 11 the the DT cord-006870-f5w6fw6q 1523 12 physiologic physiologic JJ cord-006870-f5w6fw6q 1523 13 , , , cord-006870-f5w6fw6q 1523 14 laboratory laboratory NN cord-006870-f5w6fw6q 1523 15 , , , cord-006870-f5w6fw6q 1523 16 and and CC cord-006870-f5w6fw6q 1523 17 radiographic radiographic JJ cord-006870-f5w6fw6q 1523 18 data datum NNS cord-006870-f5w6fw6q 1523 19 of of IN cord-006870-f5w6fw6q 1523 20 these these DT cord-006870-f5w6fw6q 1523 21 patients patient NNS cord-006870-f5w6fw6q 1523 22 as as RB cord-006870-f5w6fw6q 1523 23 well well RB cord-006870-f5w6fw6q 1523 24 as as IN cord-006870-f5w6fw6q 1523 25 survival survival NN cord-006870-f5w6fw6q 1523 26 or or CC cord-006870-f5w6fw6q 1523 27 cause cause NN cord-006870-f5w6fw6q 1523 28 of of IN cord-006870-f5w6fw6q 1523 29 death death NN cord-006870-f5w6fw6q 1523 30 by by IN cord-006870-f5w6fw6q 1523 31 30 30 CD cord-006870-f5w6fw6q 1523 32 days day NNS cord-006870-f5w6fw6q 1523 33 or or CC cord-006870-f5w6fw6q 1523 34 by by IN cord-006870-f5w6fw6q 1523 35 discharge discharge NN cord-006870-f5w6fw6q 1523 36 . . . cord-006870-f5w6fw6q 1524 1 Results result NNS cord-006870-f5w6fw6q 1524 2 : : : cord-006870-f5w6fw6q 1525 1 During during IN cord-006870-f5w6fw6q 1525 2 the the DT cord-006870-f5w6fw6q 1525 3 analysis analysis NN cord-006870-f5w6fw6q 1525 4 , , , cord-006870-f5w6fw6q 1525 5 51 51 CD cord-006870-f5w6fw6q 1525 6 patients patient NNS cord-006870-f5w6fw6q 1525 7 were be VBD cord-006870-f5w6fw6q 1525 8 reviewed review VBN cord-006870-f5w6fw6q 1525 9 , , , cord-006870-f5w6fw6q 1525 10 7 7 CD cord-006870-f5w6fw6q 1525 11 of of IN cord-006870-f5w6fw6q 1525 12 which which WDT cord-006870-f5w6fw6q 1525 13 ( ( -LRB- cord-006870-f5w6fw6q 1525 14 13.7 13.7 CD cord-006870-f5w6fw6q 1525 15 % % NN cord-006870-f5w6fw6q 1525 16 ) ) -RRB- cord-006870-f5w6fw6q 1525 17 had have VBD cord-006870-f5w6fw6q 1525 18 intracranial intracranial JJ cord-006870-f5w6fw6q 1525 19 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1525 20 . . . cord-006870-f5w6fw6q 1526 1 One one CD cord-006870-f5w6fw6q 1526 2 patient patient NN cord-006870-f5w6fw6q 1526 3 was be VBD cord-006870-f5w6fw6q 1526 4 excluded exclude VBN cord-006870-f5w6fw6q 1526 5 from from IN cord-006870-f5w6fw6q 1526 6 analysis analysis NN cord-006870-f5w6fw6q 1526 7 after after IN cord-006870-f5w6fw6q 1526 8 care care NN cord-006870-f5w6fw6q 1526 9 was be VBD cord-006870-f5w6fw6q 1526 10 transitioned transition VBN cord-006870-f5w6fw6q 1526 11 to to IN cord-006870-f5w6fw6q 1526 12 hospice hospice NN cord-006870-f5w6fw6q 1526 13 , , , cord-006870-f5w6fw6q 1526 14 thus thus RB cord-006870-f5w6fw6q 1526 15 follow follow NN cord-006870-f5w6fw6q 1526 16 - - HYPH cord-006870-f5w6fw6q 1526 17 up up NN cord-006870-f5w6fw6q 1526 18 scans scan NNS cord-006870-f5w6fw6q 1526 19 were be VBD cord-006870-f5w6fw6q 1526 20 not not RB cord-006870-f5w6fw6q 1526 21 obtained obtain VBN cord-006870-f5w6fw6q 1526 22 . . . cord-006870-f5w6fw6q 1527 1 The the DT cord-006870-f5w6fw6q 1527 2 remaining remain VBG cord-006870-f5w6fw6q 1527 3 6 6 CD cord-006870-f5w6fw6q 1527 4 patients patient NNS cord-006870-f5w6fw6q 1527 5 were be VBD cord-006870-f5w6fw6q 1527 6 receiving receive VBG cord-006870-f5w6fw6q 1527 7 both both DT cord-006870-f5w6fw6q 1527 8 aspirin aspirin NN cord-006870-f5w6fw6q 1527 9 ( ( -LRB- cord-006870-f5w6fw6q 1527 10 81 81 CD cord-006870-f5w6fw6q 1527 11 - - SYM cord-006870-f5w6fw6q 1527 12 325 325 CD cord-006870-f5w6fw6q 1527 13 mg mg NNP cord-006870-f5w6fw6q 1527 14 daily daily JJ cord-006870-f5w6fw6q 1527 15 ) ) -RRB- cord-006870-f5w6fw6q 1527 16 and and CC cord-006870-f5w6fw6q 1527 17 warfarin warfarin NNP cord-006870-f5w6fw6q 1527 18 ( ( -LRB- cord-006870-f5w6fw6q 1527 19 2 2 CD cord-006870-f5w6fw6q 1527 20 - - SYM cord-006870-f5w6fw6q 1527 21 8 8 CD cord-006870-f5w6fw6q 1527 22 mg mg NNP cord-006870-f5w6fw6q 1527 23 daily daily RB cord-006870-f5w6fw6q 1527 24 ) ) -RRB- cord-006870-f5w6fw6q 1527 25 with with IN cord-006870-f5w6fw6q 1527 26 an an DT cord-006870-f5w6fw6q 1527 27 INR INR NNP cord-006870-f5w6fw6q 1527 28 of of IN cord-006870-f5w6fw6q 1527 29 1.5 1.5 CD cord-006870-f5w6fw6q 1527 30 - - SYM cord-006870-f5w6fw6q 1527 31 3.3 3.3 CD cord-006870-f5w6fw6q 1528 1 ( ( -LRB- cord-006870-f5w6fw6q 1528 2 mean=2.8 mean=2.8 NN cord-006870-f5w6fw6q 1528 3 ) ) -RRB- cord-006870-f5w6fw6q 1528 4 at at IN cord-006870-f5w6fw6q 1528 5 the the DT cord-006870-f5w6fw6q 1528 6 time time NN cord-006870-f5w6fw6q 1528 7 of of IN cord-006870-f5w6fw6q 1528 8 ICH ICH NNP cord-006870-f5w6fw6q 1528 9 . . . cord-006870-f5w6fw6q 1529 1 Aspirin aspirin NN cord-006870-f5w6fw6q 1529 2 ( ( -LRB- cord-006870-f5w6fw6q 1529 3 81 81 CD cord-006870-f5w6fw6q 1529 4 - - SYM cord-006870-f5w6fw6q 1529 5 325 325 CD cord-006870-f5w6fw6q 1529 6 mg mg NNP cord-006870-f5w6fw6q 1529 7 daily daily NN cord-006870-f5w6fw6q 1529 8 ) ) -RRB- cord-006870-f5w6fw6q 1529 9 was be VBD cord-006870-f5w6fw6q 1529 10 resumed resume VBN cord-006870-f5w6fw6q 1529 11 within within IN cord-006870-f5w6fw6q 1529 12 1 1 CD cord-006870-f5w6fw6q 1529 13 - - SYM cord-006870-f5w6fw6q 1529 14 2 2 CD cord-006870-f5w6fw6q 1530 1 ( ( -LRB- cord-006870-f5w6fw6q 1530 2 mean=1.1 mean=1.1 NNP cord-006870-f5w6fw6q 1530 3 ) ) -RRB- cord-006870-f5w6fw6q 1530 4 days day NNS cord-006870-f5w6fw6q 1530 5 post post NN cord-006870-f5w6fw6q 1530 6 ICH ICH NNP cord-006870-f5w6fw6q 1530 7 . . . cord-006870-f5w6fw6q 1531 1 Warfarin Warfarin NNP cord-006870-f5w6fw6q 1531 2 was be VBD cord-006870-f5w6fw6q 1531 3 resumed resume VBN cord-006870-f5w6fw6q 1531 4 1 1 CD cord-006870-f5w6fw6q 1531 5 - - SYM cord-006870-f5w6fw6q 1531 6 20 20 CD cord-006870-f5w6fw6q 1532 1 ( ( -LRB- cord-006870-f5w6fw6q 1532 2 mean=6.6 mean=6.6 NNP cord-006870-f5w6fw6q 1532 3 ) ) -RRB- cord-006870-f5w6fw6q 1532 4 days day NNS cord-006870-f5w6fw6q 1532 5 post post NN cord-006870-f5w6fw6q 1532 6 ICH ICH NNP cord-006870-f5w6fw6q 1532 7 at at IN cord-006870-f5w6fw6q 1532 8 2 2 CD cord-006870-f5w6fw6q 1532 9 - - SYM cord-006870-f5w6fw6q 1532 10 8 8 CD cord-006870-f5w6fw6q 1532 11 mg mg NNP cord-006870-f5w6fw6q 1532 12 ( ( -LRB- cord-006870-f5w6fw6q 1532 13 mean=4 mean=4 DT cord-006870-f5w6fw6q 1532 14 mg mg NNP cord-006870-f5w6fw6q 1532 15 ) ) -RRB- cord-006870-f5w6fw6q 1532 16 with with IN cord-006870-f5w6fw6q 1532 17 goal goal NN cord-006870-f5w6fw6q 1532 18 INR INR NNP cord-006870-f5w6fw6q 1532 19 ( ( -LRB- cord-006870-f5w6fw6q 1532 20 1.7 1.7 CD cord-006870-f5w6fw6q 1532 21 - - HYPH cord-006870-f5w6fw6q 1532 22 2)-(2 2)-(2 CD cord-006870-f5w6fw6q 1532 23 - - SYM cord-006870-f5w6fw6q 1532 24 3 3 CD cord-006870-f5w6fw6q 1532 25 ) ) -RRB- cord-006870-f5w6fw6q 1532 26 depending depend VBG cord-006870-f5w6fw6q 1532 27 on on IN cord-006870-f5w6fw6q 1532 28 device device NN cord-006870-f5w6fw6q 1532 29 . . . cord-006870-f5w6fw6q 1533 1 There there EX cord-006870-f5w6fw6q 1533 2 was be VBD cord-006870-f5w6fw6q 1533 3 1 1 CD cord-006870-f5w6fw6q 1533 4 death death NN cord-006870-f5w6fw6q 1533 5 due due IN cord-006870-f5w6fw6q 1533 6 to to IN cord-006870-f5w6fw6q 1533 7 withdrawal withdrawal NN cord-006870-f5w6fw6q 1533 8 of of IN cord-006870-f5w6fw6q 1533 9 life life NN cord-006870-f5w6fw6q 1533 10 support support NN cord-006870-f5w6fw6q 1533 11 in in IN cord-006870-f5w6fw6q 1533 12 setting setting NN cord-006870-f5w6fw6q 1533 13 of of IN cord-006870-f5w6fw6q 1533 14 multiple multiple JJ cord-006870-f5w6fw6q 1533 15 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 1533 16 , , , cord-006870-f5w6fw6q 1533 17 though though IN cord-006870-f5w6fw6q 1533 18 follow follow NN cord-006870-f5w6fw6q 1533 19 - - HYPH cord-006870-f5w6fw6q 1533 20 up up NN cord-006870-f5w6fw6q 1533 21 scan scan JJ cord-006870-f5w6fw6q 1533 22 7 7 CD cord-006870-f5w6fw6q 1533 23 days day NNS cord-006870-f5w6fw6q 1533 24 post post NN cord-006870-f5w6fw6q 1534 1 warfarin warfarin JJ cord-006870-f5w6fw6q 1534 2 resumption resumption NN cord-006870-f5w6fw6q 1534 3 revealed reveal VBD cord-006870-f5w6fw6q 1534 4 no no DT cord-006870-f5w6fw6q 1534 5 evidence evidence NN cord-006870-f5w6fw6q 1534 6 of of IN cord-006870-f5w6fw6q 1534 7 rebleed rebleed NNP cord-006870-f5w6fw6q 1534 8 . . . cord-006870-f5w6fw6q 1535 1 The the DT cord-006870-f5w6fw6q 1535 2 remaining remain VBG cord-006870-f5w6fw6q 1535 3 5 5 CD cord-006870-f5w6fw6q 1535 4 patients patient NNS cord-006870-f5w6fw6q 1535 5 showed show VBD cord-006870-f5w6fw6q 1535 6 no no DT cord-006870-f5w6fw6q 1535 7 evidence evidence NN cord-006870-f5w6fw6q 1535 8 of of IN cord-006870-f5w6fw6q 1535 9 rebleed rebleed NNP cord-006870-f5w6fw6q 1535 10 on on IN cord-006870-f5w6fw6q 1535 11 CT CT NNP cord-006870-f5w6fw6q 1535 12 scans scan NNS cord-006870-f5w6fw6q 1535 13 at at IN cord-006870-f5w6fw6q 1535 14 2 2 CD cord-006870-f5w6fw6q 1535 15 months month NNS cord-006870-f5w6fw6q 1535 16 post post VBP cord-006870-f5w6fw6q 1535 17 warfarin warfarin JJ cord-006870-f5w6fw6q 1535 18 resumption resumption NN cord-006870-f5w6fw6q 1535 19 and and CC cord-006870-f5w6fw6q 1535 20 were be VBD cord-006870-f5w6fw6q 1535 21 subsequently subsequently RB cord-006870-f5w6fw6q 1535 22 discharged discharge VBN cord-006870-f5w6fw6q 1535 23 to to IN cord-006870-f5w6fw6q 1535 24 rehab rehab NN cord-006870-f5w6fw6q 1535 25 facilities facility NNS cord-006870-f5w6fw6q 1535 26 or or CC cord-006870-f5w6fw6q 1535 27 home home RB cord-006870-f5w6fw6q 1535 28 with with IN cord-006870-f5w6fw6q 1535 29 Modified Modified NNP cord-006870-f5w6fw6q 1535 30 Rankin Rankin NNP cord-006870-f5w6fw6q 1535 31 Scores score NNS cord-006870-f5w6fw6q 1535 32 0 0 CD cord-006870-f5w6fw6q 1535 33 - - SYM cord-006870-f5w6fw6q 1535 34 4 4 CD cord-006870-f5w6fw6q 1536 1 ( ( -LRB- cord-006870-f5w6fw6q 1536 2 mean=2.8 mean=2.8 NN cord-006870-f5w6fw6q 1536 3 ) ) -RRB- cord-006870-f5w6fw6q 1536 4 . . . cord-006870-f5w6fw6q 1537 1 Conclusion conclusion NN cord-006870-f5w6fw6q 1537 2 : : : cord-006870-f5w6fw6q 1538 1 In in IN cord-006870-f5w6fw6q 1538 2 this this DT cord-006870-f5w6fw6q 1538 3 review review NN cord-006870-f5w6fw6q 1538 4 of of IN cord-006870-f5w6fw6q 1538 5 51 51 CD cord-006870-f5w6fw6q 1538 6 LVAD LVAD NNP cord-006870-f5w6fw6q 1538 7 patients patient NNS cord-006870-f5w6fw6q 1538 8 , , , cord-006870-f5w6fw6q 1538 9 about about RB cord-006870-f5w6fw6q 1538 10 13 13 CD cord-006870-f5w6fw6q 1538 11 % % NN cord-006870-f5w6fw6q 1538 12 suffered suffer VBD cord-006870-f5w6fw6q 1538 13 ICH ICH NNP cord-006870-f5w6fw6q 1538 14 , , , cord-006870-f5w6fw6q 1538 15 and and CC cord-006870-f5w6fw6q 1538 16 of of IN cord-006870-f5w6fw6q 1538 17 those those DT cord-006870-f5w6fw6q 1538 18 6 6 CD cord-006870-f5w6fw6q 1538 19 survivors survivor NNS cord-006870-f5w6fw6q 1538 20 aspirin aspirin NN cord-006870-f5w6fw6q 1538 21 was be VBD cord-006870-f5w6fw6q 1538 22 safely safely RB cord-006870-f5w6fw6q 1538 23 resumed resume VBN cord-006870-f5w6fw6q 1538 24 within within IN cord-006870-f5w6fw6q 1538 25 2 2 CD cord-006870-f5w6fw6q 1538 26 days day NNS cord-006870-f5w6fw6q 1538 27 and and CC cord-006870-f5w6fw6q 1538 28 warfarin warfarin NN cord-006870-f5w6fw6q 1538 29 was be VBD cord-006870-f5w6fw6q 1538 30 safely safely RB cord-006870-f5w6fw6q 1538 31 resumed resume VBN cord-006870-f5w6fw6q 1538 32 as as RB cord-006870-f5w6fw6q 1538 33 early early RB cord-006870-f5w6fw6q 1538 34 as as IN cord-006870-f5w6fw6q 1538 35 7 7 CD cord-006870-f5w6fw6q 1538 36 days day NNS cord-006870-f5w6fw6q 1538 37 post post NN cord-006870-f5w6fw6q 1538 38 - - NN cord-006870-f5w6fw6q 1538 39 event event NN cord-006870-f5w6fw6q 1538 40 . . . cord-006870-f5w6fw6q 1539 1 Further further JJ cord-006870-f5w6fw6q 1539 2 studies study NNS cord-006870-f5w6fw6q 1539 3 are be VBP cord-006870-f5w6fw6q 1539 4 needed need VBN cord-006870-f5w6fw6q 1539 5 in in IN cord-006870-f5w6fw6q 1539 6 order order NN cord-006870-f5w6fw6q 1539 7 to to TO cord-006870-f5w6fw6q 1539 8 establish establish VB cord-006870-f5w6fw6q 1539 9 safe safe JJ cord-006870-f5w6fw6q 1539 10 practice practice NN cord-006870-f5w6fw6q 1539 11 guidelines guideline NNS cord-006870-f5w6fw6q 1539 12 and and CC cord-006870-f5w6fw6q 1539 13 risk risk NN cord-006870-f5w6fw6q 1539 14 factors factor NNS cord-006870-f5w6fw6q 1539 15 to to TO cord-006870-f5w6fw6q 1539 16 prevent prevent VB cord-006870-f5w6fw6q 1539 17 ICH ICH NNP cord-006870-f5w6fw6q 1539 18 . . . cord-006870-f5w6fw6q 1540 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1540 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1540 3 ( ( -LRB- cord-006870-f5w6fw6q 1540 4 ICH ICH NNP cord-006870-f5w6fw6q 1540 5 ) ) -RRB- cord-006870-f5w6fw6q 1540 6 remains remain VBZ cord-006870-f5w6fw6q 1540 7 a a DT cord-006870-f5w6fw6q 1540 8 devastating devastating JJ cord-006870-f5w6fw6q 1540 9 form form NN cord-006870-f5w6fw6q 1540 10 of of IN cord-006870-f5w6fw6q 1540 11 stroke stroke NN cord-006870-f5w6fw6q 1540 12 , , , cord-006870-f5w6fw6q 1540 13 and and CC cord-006870-f5w6fw6q 1540 14 perihematomal perihematomal NN cord-006870-f5w6fw6q 1540 15 edema edema NN cord-006870-f5w6fw6q 1540 16 worsen worsen NN cord-006870-f5w6fw6q 1540 17 outcomes outcome NNS cord-006870-f5w6fw6q 1540 18 after after IN cord-006870-f5w6fw6q 1540 19 ICH ICH NNP cord-006870-f5w6fw6q 1540 20 . . . cord-006870-f5w6fw6q 1541 1 Recent recent JJ cord-006870-f5w6fw6q 1541 2 studies study NNS cord-006870-f5w6fw6q 1541 3 have have VBP cord-006870-f5w6fw6q 1541 4 demonstrated demonstrate VBN cord-006870-f5w6fw6q 1541 5 the the DT cord-006870-f5w6fw6q 1541 6 safety safety NN cord-006870-f5w6fw6q 1541 7 of of IN cord-006870-f5w6fw6q 1541 8 minimally minimally RB cord-006870-f5w6fw6q 1541 9 invasive invasive JJ cord-006870-f5w6fw6q 1541 10 surgery surgery NN cord-006870-f5w6fw6q 1541 11 ( ( -LRB- cord-006870-f5w6fw6q 1541 12 MIS MIS NNP cord-006870-f5w6fw6q 1541 13 ) ) -RRB- cord-006870-f5w6fw6q 1541 14 for for IN cord-006870-f5w6fw6q 1541 15 hematoma hematoma NN cord-006870-f5w6fw6q 1541 16 removal removal NN cord-006870-f5w6fw6q 1541 17 , , , cord-006870-f5w6fw6q 1541 18 but but CC cord-006870-f5w6fw6q 1541 19 the the DT cord-006870-f5w6fw6q 1541 20 efficacy efficacy NN cord-006870-f5w6fw6q 1541 21 of of IN cord-006870-f5w6fw6q 1541 22 MIS MIS NNP cord-006870-f5w6fw6q 1541 23 in in IN cord-006870-f5w6fw6q 1541 24 the the DT cord-006870-f5w6fw6q 1541 25 treatment treatment NN cord-006870-f5w6fw6q 1541 26 of of IN cord-006870-f5w6fw6q 1541 27 ICH ICH NNP cord-006870-f5w6fw6q 1541 28 is be VBZ cord-006870-f5w6fw6q 1541 29 controversial controversial JJ cord-006870-f5w6fw6q 1541 30 . . . cord-006870-f5w6fw6q 1542 1 This this DT cord-006870-f5w6fw6q 1542 2 study study NN cord-006870-f5w6fw6q 1542 3 aimed aim VBD cord-006870-f5w6fw6q 1542 4 to to TO cord-006870-f5w6fw6q 1542 5 evaluate evaluate VB cord-006870-f5w6fw6q 1542 6 the the DT cord-006870-f5w6fw6q 1542 7 effect effect NN cord-006870-f5w6fw6q 1542 8 of of IN cord-006870-f5w6fw6q 1542 9 MIS mi NNS cord-006870-f5w6fw6q 1542 10 compared compare VBN cord-006870-f5w6fw6q 1542 11 with with IN cord-006870-f5w6fw6q 1542 12 medical medical JJ cord-006870-f5w6fw6q 1542 13 treatment treatment NN cord-006870-f5w6fw6q 1542 14 for for IN cord-006870-f5w6fw6q 1542 15 basal basal NN cord-006870-f5w6fw6q 1542 16 ganglia ganglion NNS cord-006870-f5w6fw6q 1542 17 ICH ICH NNP cord-006870-f5w6fw6q 1542 18 . . . cord-006870-f5w6fw6q 1543 1 We -PRON- PRP cord-006870-f5w6fw6q 1543 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 1543 3 analyzed analyze VBD cord-006870-f5w6fw6q 1543 4 the the DT cord-006870-f5w6fw6q 1543 5 clinical clinical JJ cord-006870-f5w6fw6q 1543 6 outcomes outcome NNS cord-006870-f5w6fw6q 1543 7 of of IN cord-006870-f5w6fw6q 1543 8 prospectively prospectively RB cord-006870-f5w6fw6q 1543 9 collected collect VBN cord-006870-f5w6fw6q 1543 10 data datum NNS cord-006870-f5w6fw6q 1543 11 from from IN cord-006870-f5w6fw6q 1543 12 two two CD cord-006870-f5w6fw6q 1543 13 stroke stroke NN cord-006870-f5w6fw6q 1543 14 centers center NNS cord-006870-f5w6fw6q 1543 15 . . . cord-006870-f5w6fw6q 1544 1 The the DT cord-006870-f5w6fw6q 1544 2 treatment treatment NN cord-006870-f5w6fw6q 1544 3 strategies strategy NNS cord-006870-f5w6fw6q 1544 4 of of IN cord-006870-f5w6fw6q 1544 5 the the DT cord-006870-f5w6fw6q 1544 6 two two CD cord-006870-f5w6fw6q 1544 7 stroke stroke NN cord-006870-f5w6fw6q 1544 8 centers center NNS cord-006870-f5w6fw6q 1544 9 for for IN cord-006870-f5w6fw6q 1544 10 basal basal NN cord-006870-f5w6fw6q 1544 11 ganglia ganglion NNS cord-006870-f5w6fw6q 1544 12 ICH ICH NNP cord-006870-f5w6fw6q 1544 13 are be VBP cord-006870-f5w6fw6q 1544 14 different different JJ cord-006870-f5w6fw6q 1544 15 ; ; : cord-006870-f5w6fw6q 1544 16 one one CD cord-006870-f5w6fw6q 1544 17 stroke stroke NN cord-006870-f5w6fw6q 1544 18 center center NN cord-006870-f5w6fw6q 1544 19 underwent undergo VBD cord-006870-f5w6fw6q 1544 20 MIS MIS NNP cord-006870-f5w6fw6q 1544 21 and and CC cord-006870-f5w6fw6q 1544 22 the the DT cord-006870-f5w6fw6q 1544 23 other other JJ cord-006870-f5w6fw6q 1544 24 stroke stroke NN cord-006870-f5w6fw6q 1544 25 center center NN cord-006870-f5w6fw6q 1544 26 medically medically RB cord-006870-f5w6fw6q 1544 27 treated treat VBN cord-006870-f5w6fw6q 1544 28 according accord VBG cord-006870-f5w6fw6q 1544 29 to to IN cord-006870-f5w6fw6q 1544 30 the the DT cord-006870-f5w6fw6q 1544 31 current current JJ cord-006870-f5w6fw6q 1544 32 guidelines guideline NNS cord-006870-f5w6fw6q 1544 33 . . . cord-006870-f5w6fw6q 1545 1 We -PRON- PRP cord-006870-f5w6fw6q 1545 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 1545 3 that that IN cord-006870-f5w6fw6q 1545 4 MIS MIS NNP cord-006870-f5w6fw6q 1545 5 could could MD cord-006870-f5w6fw6q 1545 6 reduce reduce VB cord-006870-f5w6fw6q 1545 7 perihematomal perihematomal NN cord-006870-f5w6fw6q 1545 8 edema edema NN cord-006870-f5w6fw6q 1545 9 and and CC cord-006870-f5w6fw6q 1545 10 improve improve VB cord-006870-f5w6fw6q 1545 11 functional functional JJ cord-006870-f5w6fw6q 1545 12 outcomes outcome NNS cord-006870-f5w6fw6q 1545 13 compared compare VBN cord-006870-f5w6fw6q 1545 14 to to IN cord-006870-f5w6fw6q 1545 15 medical medical JJ cord-006870-f5w6fw6q 1545 16 treatment treatment NN cord-006870-f5w6fw6q 1545 17 . . . cord-006870-f5w6fw6q 1546 1 Primary primary JJ cord-006870-f5w6fw6q 1546 2 outcome outcome NN cord-006870-f5w6fw6q 1546 3 of of IN cord-006870-f5w6fw6q 1546 4 this this DT cord-006870-f5w6fw6q 1546 5 study study NN cord-006870-f5w6fw6q 1546 6 was be VBD cord-006870-f5w6fw6q 1546 7 a a DT cord-006870-f5w6fw6q 1546 8 modified modify VBN cord-006870-f5w6fw6q 1546 9 Rankin Rankin NNP cord-006870-f5w6fw6q 1546 10 scale scale NN cord-006870-f5w6fw6q 1546 11 ( ( -LRB- cord-006870-f5w6fw6q 1546 12 mRS mrs UH cord-006870-f5w6fw6q 1546 13 ) ) -RRB- cord-006870-f5w6fw6q 1546 14 at at IN cord-006870-f5w6fw6q 1546 15 3 3 CD cord-006870-f5w6fw6q 1546 16 months month NNS cord-006870-f5w6fw6q 1546 17 after after IN cord-006870-f5w6fw6q 1546 18 ICH ICH NNP cord-006870-f5w6fw6q 1546 19 occurrence occurrence NN cord-006870-f5w6fw6q 1546 20 . . . cord-006870-f5w6fw6q 1547 1 A a DT cord-006870-f5w6fw6q 1547 2 total total NN cord-006870-f5w6fw6q 1547 3 of of IN cord-006870-f5w6fw6q 1547 4 155 155 CD cord-006870-f5w6fw6q 1547 5 patients patient NNS cord-006870-f5w6fw6q 1547 6 with with IN cord-006870-f5w6fw6q 1547 7 basal basal NN cord-006870-f5w6fw6q 1547 8 ganglia ganglion NNS cord-006870-f5w6fw6q 1547 9 ICH ICH NNP cord-006870-f5w6fw6q 1547 10 were be VBD cord-006870-f5w6fw6q 1547 11 treated treat VBN cord-006870-f5w6fw6q 1547 12 with with IN cord-006870-f5w6fw6q 1547 13 different different JJ cord-006870-f5w6fw6q 1547 14 treatment treatment NN cord-006870-f5w6fw6q 1547 15 strategies strategy NNS cord-006870-f5w6fw6q 1547 16 ; ; : cord-006870-f5w6fw6q 1547 17 86 86 CD cord-006870-f5w6fw6q 1547 18 patients patient NNS cord-006870-f5w6fw6q 1547 19 underwent undergo VBD cord-006870-f5w6fw6q 1547 20 MIS MIS NNP cord-006870-f5w6fw6q 1547 21 and and CC cord-006870-f5w6fw6q 1547 22 69 69 CD cord-006870-f5w6fw6q 1547 23 patients patient NNS cord-006870-f5w6fw6q 1547 24 received receive VBD cord-006870-f5w6fw6q 1547 25 medical medical JJ cord-006870-f5w6fw6q 1547 26 treatment treatment NN cord-006870-f5w6fw6q 1547 27 . . . cord-006870-f5w6fw6q 1548 1 No no DT cord-006870-f5w6fw6q 1548 2 statistically statistically RB cord-006870-f5w6fw6q 1548 3 significant significant JJ cord-006870-f5w6fw6q 1548 4 differences difference NNS cord-006870-f5w6fw6q 1548 5 were be VBD cord-006870-f5w6fw6q 1548 6 found find VBN cord-006870-f5w6fw6q 1548 7 in in IN cord-006870-f5w6fw6q 1548 8 age age NN cord-006870-f5w6fw6q 1548 9 , , , cord-006870-f5w6fw6q 1548 10 sex sex NN cord-006870-f5w6fw6q 1548 11 , , , cord-006870-f5w6fw6q 1548 12 hematoma hematoma NN cord-006870-f5w6fw6q 1548 13 volume volume NN cord-006870-f5w6fw6q 1548 14 , , , cord-006870-f5w6fw6q 1548 15 and and CC cord-006870-f5w6fw6q 1548 16 Glasgow Glasgow NNP cord-006870-f5w6fw6q 1548 17 Coma Coma NNP cord-006870-f5w6fw6q 1548 18 Scale Scale NNP cord-006870-f5w6fw6q 1548 19 scores score NNS cord-006870-f5w6fw6q 1548 20 between between IN cord-006870-f5w6fw6q 1548 21 the the DT cord-006870-f5w6fw6q 1548 22 groups group NNS cord-006870-f5w6fw6q 1548 23 . . . cord-006870-f5w6fw6q 1549 1 A a DT cord-006870-f5w6fw6q 1549 2 better well JJR cord-006870-f5w6fw6q 1549 3 functional functional JJ cord-006870-f5w6fw6q 1549 4 recovery recovery NN cord-006870-f5w6fw6q 1549 5 ( ( -LRB- cord-006870-f5w6fw6q 1549 6 mRS mrs VB cord-006870-f5w6fw6q 1549 7 < < XX cord-006870-f5w6fw6q 1549 8 3 3 CD cord-006870-f5w6fw6q 1549 9 ) ) -RRB- cord-006870-f5w6fw6q 1549 10 at at IN cord-006870-f5w6fw6q 1549 11 3 3 CD cord-006870-f5w6fw6q 1549 12 months month NNS cord-006870-f5w6fw6q 1549 13 was be VBD cord-006870-f5w6fw6q 1549 14 found find VBN cord-006870-f5w6fw6q 1549 15 in in IN cord-006870-f5w6fw6q 1549 16 the the DT cord-006870-f5w6fw6q 1549 17 medical medical JJ cord-006870-f5w6fw6q 1549 18 treatment treatment NN cord-006870-f5w6fw6q 1549 19 group group NN cord-006870-f5w6fw6q 1549 20 than than IN cord-006870-f5w6fw6q 1549 21 the the DT cord-006870-f5w6fw6q 1549 22 MIS MIS NNP cord-006870-f5w6fw6q 1549 23 group group NN cord-006870-f5w6fw6q 1549 24 ( ( -LRB- cord-006870-f5w6fw6q 1549 25 46.4 46.4 CD cord-006870-f5w6fw6q 1549 26 % % NN cord-006870-f5w6fw6q 1549 27 vs vs IN cord-006870-f5w6fw6q 1549 28 14.0 14.0 CD cord-006870-f5w6fw6q 1549 29 % % NN cord-006870-f5w6fw6q 1549 30 , , , cord-006870-f5w6fw6q 1549 31 p p NN cord-006870-f5w6fw6q 1549 32 < < XX cord-006870-f5w6fw6q 1549 33 0.05 0.05 CD cord-006870-f5w6fw6q 1549 34 ) ) -RRB- cord-006870-f5w6fw6q 1549 35 . . . cord-006870-f5w6fw6q 1550 1 No no DT cord-006870-f5w6fw6q 1550 2 significant significant JJ cord-006870-f5w6fw6q 1550 3 differences difference NNS cord-006870-f5w6fw6q 1550 4 were be VBD cord-006870-f5w6fw6q 1550 5 observed observe VBN cord-006870-f5w6fw6q 1550 6 between between IN cord-006870-f5w6fw6q 1550 7 groups group NNS cord-006870-f5w6fw6q 1550 8 in in IN cord-006870-f5w6fw6q 1550 9 terms term NNS cord-006870-f5w6fw6q 1550 10 of of IN cord-006870-f5w6fw6q 1550 11 mortality mortality NN cord-006870-f5w6fw6q 1550 12 . . . cord-006870-f5w6fw6q 1551 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1551 2 findings finding NNS cord-006870-f5w6fw6q 1551 3 suggest suggest VBP cord-006870-f5w6fw6q 1551 4 that that IN cord-006870-f5w6fw6q 1551 5 the the DT cord-006870-f5w6fw6q 1551 6 best good JJS cord-006870-f5w6fw6q 1551 7 medical medical JJ cord-006870-f5w6fw6q 1551 8 treatment treatment NN cord-006870-f5w6fw6q 1551 9 improves improve VBZ cord-006870-f5w6fw6q 1551 10 functional functional JJ cord-006870-f5w6fw6q 1551 11 recovery recovery NN cord-006870-f5w6fw6q 1551 12 after after IN cord-006870-f5w6fw6q 1551 13 basal basal NN cord-006870-f5w6fw6q 1551 14 ganglia ganglion NNS cord-006870-f5w6fw6q 1551 15 ICH ICH NNP cord-006870-f5w6fw6q 1551 16 compared compare VBN cord-006870-f5w6fw6q 1551 17 to to IN cord-006870-f5w6fw6q 1551 18 MIS MIS NNP cord-006870-f5w6fw6q 1551 19 . . . cord-006870-f5w6fw6q 1552 1 These these DT cord-006870-f5w6fw6q 1552 2 results result NNS cord-006870-f5w6fw6q 1552 3 are be VBP cord-006870-f5w6fw6q 1552 4 contrary contrary JJ cord-006870-f5w6fw6q 1552 5 to to IN cord-006870-f5w6fw6q 1552 6 other other JJ cord-006870-f5w6fw6q 1552 7 studies study NNS cord-006870-f5w6fw6q 1552 8 of of IN cord-006870-f5w6fw6q 1552 9 ICH ICH NNP cord-006870-f5w6fw6q 1552 10 , , , cord-006870-f5w6fw6q 1552 11 and and CC cord-006870-f5w6fw6q 1552 12 further further JJ cord-006870-f5w6fw6q 1552 13 randomized randomized JJ cord-006870-f5w6fw6q 1552 14 trials trial NNS cord-006870-f5w6fw6q 1552 15 are be VBP cord-006870-f5w6fw6q 1552 16 required require VBN cord-006870-f5w6fw6q 1552 17 . . . cord-006870-f5w6fw6q 1553 1 Perihematomal perihematomal NN cord-006870-f5w6fw6q 1553 2 edema edema NN cord-006870-f5w6fw6q 1553 3 ( ( -LRB- cord-006870-f5w6fw6q 1553 4 PHE PHE NNP cord-006870-f5w6fw6q 1553 5 ) ) -RRB- cord-006870-f5w6fw6q 1553 6 after after IN cord-006870-f5w6fw6q 1553 7 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1553 8 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1553 9 ( ( -LRB- cord-006870-f5w6fw6q 1553 10 ICH ICH NNP cord-006870-f5w6fw6q 1553 11 ) ) -RRB- cord-006870-f5w6fw6q 1553 12 is be VBZ cord-006870-f5w6fw6q 1553 13 thought think VBN cord-006870-f5w6fw6q 1553 14 to to TO cord-006870-f5w6fw6q 1553 15 be be VB cord-006870-f5w6fw6q 1553 16 predominantly predominantly RB cord-006870-f5w6fw6q 1553 17 vasogenic vasogenic JJ cord-006870-f5w6fw6q 1553 18 . . . cord-006870-f5w6fw6q 1554 1 The the DT cord-006870-f5w6fw6q 1554 2 presence presence NN cord-006870-f5w6fw6q 1554 3 and and CC cord-006870-f5w6fw6q 1554 4 extent extent NN cord-006870-f5w6fw6q 1554 5 of of IN cord-006870-f5w6fw6q 1554 6 cytotoxic cytotoxic JJ cord-006870-f5w6fw6q 1554 7 edema edema NN cord-006870-f5w6fw6q 1554 8 ( ( -LRB- cord-006870-f5w6fw6q 1554 9 CE CE NNP cord-006870-f5w6fw6q 1554 10 ) ) -RRB- cord-006870-f5w6fw6q 1554 11 is be VBZ cord-006870-f5w6fw6q 1554 12 controversial controversial JJ cord-006870-f5w6fw6q 1554 13 . . . cord-006870-f5w6fw6q 1555 1 We -PRON- PRP cord-006870-f5w6fw6q 1555 2 investigated investigate VBD cord-006870-f5w6fw6q 1555 3 PHE phe NN cord-006870-f5w6fw6q 1555 4 diffusivity diffusivity NN cord-006870-f5w6fw6q 1555 5 ( ( -LRB- cord-006870-f5w6fw6q 1555 6 PHED PHED NNP cord-006870-f5w6fw6q 1555 7 ) ) -RRB- cord-006870-f5w6fw6q 1555 8 and and CC cord-006870-f5w6fw6q 1555 9 factors factor NNS cord-006870-f5w6fw6q 1555 10 associated associate VBN cord-006870-f5w6fw6q 1555 11 with with IN cord-006870-f5w6fw6q 1555 12 CE CE NNP cord-006870-f5w6fw6q 1555 13 . . . cord-006870-f5w6fw6q 1556 1 Consecutive consecutive JJ cord-006870-f5w6fw6q 1556 2 patients patient NNS cord-006870-f5w6fw6q 1556 3 from from IN cord-006870-f5w6fw6q 1556 4 the the DT cord-006870-f5w6fw6q 1556 5 prospective prospective JJ cord-006870-f5w6fw6q 1556 6 NIH NIH NNP cord-006870-f5w6fw6q 1556 7 funded fund VBN cord-006870-f5w6fw6q 1556 8 DASH1 DASH1 NNP cord-006870-f5w6fw6q 1556 9 study study NN cord-006870-f5w6fw6q 1556 10 ( ( -LRB- cord-006870-f5w6fw6q 1556 11 > > NFP cord-006870-f5w6fw6q 1556 12 18 18 CD cord-006870-f5w6fw6q 1556 13 years year NNS cord-006870-f5w6fw6q 1556 14 , , , cord-006870-f5w6fw6q 1556 15 primary primary JJ cord-006870-f5w6fw6q 1556 16 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1556 17 ICH ICH NNP cord-006870-f5w6fw6q 1556 18 ) ) -RRB- cord-006870-f5w6fw6q 1556 19 were be VBD cord-006870-f5w6fw6q 1556 20 included include VBN cord-006870-f5w6fw6q 1556 21 . . . cord-006870-f5w6fw6q 1557 1 PHE PHE NNP cord-006870-f5w6fw6q 1557 2 volume volume NN cord-006870-f5w6fw6q 1557 3 was be VBD cord-006870-f5w6fw6q 1557 4 outlined outline VBN cord-006870-f5w6fw6q 1557 5 on on IN cord-006870-f5w6fw6q 1557 6 T2 T2 NNP cord-006870-f5w6fw6q 1557 7 / / SYM cord-006870-f5w6fw6q 1557 8 FLAIR FLAIR NNP cord-006870-f5w6fw6q 1557 9 and and CC cord-006870-f5w6fw6q 1557 10 ICH ICH NNP cord-006870-f5w6fw6q 1557 11 volume volume NN cord-006870-f5w6fw6q 1557 12 on on IN cord-006870-f5w6fw6q 1557 13 GRE GRE NNP cord-006870-f5w6fw6q 1557 14 ; ; : cord-006870-f5w6fw6q 1557 15 these these DT cord-006870-f5w6fw6q 1557 16 and and CC cord-006870-f5w6fw6q 1557 17 ADC ADC NNP cord-006870-f5w6fw6q 1557 18 were be VBD cord-006870-f5w6fw6q 1557 19 co co JJ cord-006870-f5w6fw6q 1557 20 - - VBN cord-006870-f5w6fw6q 1557 21 registered register VBN cord-006870-f5w6fw6q 1557 22 . . . cord-006870-f5w6fw6q 1558 1 Tissue tissue NN cord-006870-f5w6fw6q 1558 2 characteristics characteristic NNS cord-006870-f5w6fw6q 1558 3 was be VBD cord-006870-f5w6fw6q 1558 4 defined define VBN cord-006870-f5w6fw6q 1558 5 as as IN cord-006870-f5w6fw6q 1558 6 : : : cord-006870-f5w6fw6q 1559 1 CE CE NNP cord-006870-f5w6fw6q 1559 2 = = SYM cord-006870-f5w6fw6q 1559 3 ADC ADC NNP cord-006870-f5w6fw6q 1559 4 1200 1200 CD cord-006870-f5w6fw6q 1559 5 x x SYM cord-006870-f5w6fw6q 1559 6 10 10 CD cord-006870-f5w6fw6q 1559 7 - - SYM cord-006870-f5w6fw6q 1559 8 6 6 CD cord-006870-f5w6fw6q 1559 9 mm2 mm2 NNPS cord-006870-f5w6fw6q 1559 10 / / SYM cord-006870-f5w6fw6q 1559 11 sec sec NNP cord-006870-f5w6fw6q 1559 12 . . . cord-006870-f5w6fw6q 1560 1 Clinical clinical JJ cord-006870-f5w6fw6q 1560 2 and and CC cord-006870-f5w6fw6q 1560 3 radiographic radiographic JJ cord-006870-f5w6fw6q 1560 4 factors factor NNS cord-006870-f5w6fw6q 1560 5 associated associate VBN cord-006870-f5w6fw6q 1560 6 with with IN cord-006870-f5w6fw6q 1560 7 CE CE NNP cord-006870-f5w6fw6q 1560 8 were be VBD cord-006870-f5w6fw6q 1560 9 determined determine VBN cord-006870-f5w6fw6q 1560 10 . . . cord-006870-f5w6fw6q 1560 11 _SP cord-006870-f5w6fw6q 1561 1 Cytotoxic cytotoxic JJ cord-006870-f5w6fw6q 1561 2 edema edema NN cord-006870-f5w6fw6q 1561 3 is be VBZ cord-006870-f5w6fw6q 1561 4 detected detect VBN cord-006870-f5w6fw6q 1561 5 in in IN cord-006870-f5w6fw6q 1561 6 the the DT cord-006870-f5w6fw6q 1561 7 perihematomal perihematomal JJ cord-006870-f5w6fw6q 1561 8 area area NN cord-006870-f5w6fw6q 1561 9 , , , cord-006870-f5w6fw6q 1561 10 early early RB cord-006870-f5w6fw6q 1561 11 after after IN cord-006870-f5w6fw6q 1561 12 ICH ICH NNP cord-006870-f5w6fw6q 1561 13 and and CC cord-006870-f5w6fw6q 1561 14 is be VBZ cord-006870-f5w6fw6q 1561 15 associated associate VBN cord-006870-f5w6fw6q 1561 16 with with IN cord-006870-f5w6fw6q 1561 17 younger young JJR cord-006870-f5w6fw6q 1561 18 age age NN cord-006870-f5w6fw6q 1561 19 , , , cord-006870-f5w6fw6q 1561 20 larger large JJR cord-006870-f5w6fw6q 1561 21 ICH ICH NNP cord-006870-f5w6fw6q 1561 22 and and CC cord-006870-f5w6fw6q 1561 23 prior prior RB cord-006870-f5w6fw6q 1561 24 h h NNP cord-006870-f5w6fw6q 1561 25 / / SYM cord-006870-f5w6fw6q 1561 26 o o NN cord-006870-f5w6fw6q 1561 27 TIA TIA NNP cord-006870-f5w6fw6q 1561 28 / / SYM cord-006870-f5w6fw6q 1561 29 stroke stroke NN cord-006870-f5w6fw6q 1561 30 . . . cord-006870-f5w6fw6q 1562 1 Its -PRON- PRP$ cord-006870-f5w6fw6q 1562 2 clinical clinical JJ cord-006870-f5w6fw6q 1562 3 significance significance NN cord-006870-f5w6fw6q 1562 4 needs need VBZ cord-006870-f5w6fw6q 1562 5 to to TO cord-006870-f5w6fw6q 1562 6 be be VB cord-006870-f5w6fw6q 1562 7 studied study VBN cord-006870-f5w6fw6q 1562 8 further further RB cord-006870-f5w6fw6q 1562 9 . . . cord-006870-f5w6fw6q 1563 1 Hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1563 2 stroke stroke NN cord-006870-f5w6fw6q 1563 3 carries carry VBZ cord-006870-f5w6fw6q 1563 4 a a DT cord-006870-f5w6fw6q 1563 5 high high JJ cord-006870-f5w6fw6q 1563 6 mortality mortality NN cord-006870-f5w6fw6q 1563 7 rate rate NN cord-006870-f5w6fw6q 1563 8 and and CC cord-006870-f5w6fw6q 1563 9 determining determine VBG cord-006870-f5w6fw6q 1563 10 prognostic prognostic JJ cord-006870-f5w6fw6q 1563 11 factors factor NNS cord-006870-f5w6fw6q 1563 12 during during IN cord-006870-f5w6fw6q 1563 13 initial initial JJ cord-006870-f5w6fw6q 1563 14 presentation presentation NN cord-006870-f5w6fw6q 1563 15 can can MD cord-006870-f5w6fw6q 1563 16 aid aid VB cord-006870-f5w6fw6q 1563 17 redirecting redirect VBG cord-006870-f5w6fw6q 1563 18 intensive intensive JJ cord-006870-f5w6fw6q 1563 19 care care NN cord-006870-f5w6fw6q 1563 20 unit unit NN cord-006870-f5w6fw6q 1563 21 ( ( -LRB- cord-006870-f5w6fw6q 1563 22 ICU ICU NNP cord-006870-f5w6fw6q 1563 23 ) ) -RRB- cord-006870-f5w6fw6q 1563 24 management management NN cord-006870-f5w6fw6q 1563 25 . . . cord-006870-f5w6fw6q 1564 1 We -PRON- PRP cord-006870-f5w6fw6q 1564 2 described describe VBD cord-006870-f5w6fw6q 1564 3 the the DT cord-006870-f5w6fw6q 1564 4 physiological physiological JJ cord-006870-f5w6fw6q 1564 5 profile profile NN cord-006870-f5w6fw6q 1564 6 and and CC cord-006870-f5w6fw6q 1564 7 clinical clinical JJ cord-006870-f5w6fw6q 1564 8 outcomes outcome NNS cord-006870-f5w6fw6q 1564 9 of of IN cord-006870-f5w6fw6q 1564 10 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1564 11 stroke stroke NN cord-006870-f5w6fw6q 1564 12 patients patient NNS cord-006870-f5w6fw6q 1564 13 in in IN cord-006870-f5w6fw6q 1564 14 a a DT cord-006870-f5w6fw6q 1564 15 Colombian colombian JJ cord-006870-f5w6fw6q 1564 16 ICU ICU NNP cord-006870-f5w6fw6q 1564 17 . . . cord-006870-f5w6fw6q 1565 1 We -PRON- PRP cord-006870-f5w6fw6q 1565 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 1565 3 reviewed review VBD cord-006870-f5w6fw6q 1565 4 all all DT cord-006870-f5w6fw6q 1565 5 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1565 6 stroke stroke NN cord-006870-f5w6fw6q 1565 7 patients patient NNS cord-006870-f5w6fw6q 1565 8 admitted admit VBN cord-006870-f5w6fw6q 1565 9 to to IN cord-006870-f5w6fw6q 1565 10 our -PRON- PRP$ cord-006870-f5w6fw6q 1565 11 ICU ICU NNP cord-006870-f5w6fw6q 1565 12 from from IN cord-006870-f5w6fw6q 1565 13 2014 2014 CD cord-006870-f5w6fw6q 1565 14 - - SYM cord-006870-f5w6fw6q 1565 15 2017 2017 CD cord-006870-f5w6fw6q 1565 16 . . . cord-006870-f5w6fw6q 1566 1 Clinical clinical JJ cord-006870-f5w6fw6q 1566 2 characteristics characteristic NNS cord-006870-f5w6fw6q 1566 3 , , , cord-006870-f5w6fw6q 1566 4 outcomes outcome NNS cord-006870-f5w6fw6q 1566 5 , , , cord-006870-f5w6fw6q 1566 6 available available JJ cord-006870-f5w6fw6q 1566 7 laboratory laboratory NN cord-006870-f5w6fw6q 1566 8 values value NNS cord-006870-f5w6fw6q 1566 9 and and CC cord-006870-f5w6fw6q 1566 10 hourly hourly JJ cord-006870-f5w6fw6q 1566 11 vital vital JJ cord-006870-f5w6fw6q 1566 12 signs sign NNS cord-006870-f5w6fw6q 1566 13 from from IN cord-006870-f5w6fw6q 1566 14 the the DT cord-006870-f5w6fw6q 1566 15 first first JJ cord-006870-f5w6fw6q 1566 16 48 48 CD cord-006870-f5w6fw6q 1566 17 hours hour NNS cord-006870-f5w6fw6q 1566 18 in in IN cord-006870-f5w6fw6q 1566 19 the the DT cord-006870-f5w6fw6q 1566 20 ICU ICU NNP cord-006870-f5w6fw6q 1566 21 were be VBD cord-006870-f5w6fw6q 1566 22 retrieved retrieve VBN cord-006870-f5w6fw6q 1566 23 and and CC cord-006870-f5w6fw6q 1566 24 analyzed analyze VBN cord-006870-f5w6fw6q 1566 25 . . . cord-006870-f5w6fw6q 1567 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1567 2 primary primary JJ cord-006870-f5w6fw6q 1567 3 stroke stroke NN cord-006870-f5w6fw6q 1567 4 center center NN cord-006870-f5w6fw6q 1567 5 admitted admit VBD cord-006870-f5w6fw6q 1567 6 395 395 CD cord-006870-f5w6fw6q 1567 7 patients patient NNS cord-006870-f5w6fw6q 1567 8 , , , cord-006870-f5w6fw6q 1567 9 72 72 CD cord-006870-f5w6fw6q 1567 10 ( ( -LRB- cord-006870-f5w6fw6q 1567 11 18 18 CD cord-006870-f5w6fw6q 1567 12 % % NN cord-006870-f5w6fw6q 1567 13 ) ) -RRB- cord-006870-f5w6fw6q 1567 14 were be VBD cord-006870-f5w6fw6q 1567 15 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1567 16 . . . cord-006870-f5w6fw6q 1568 1 Out out IN cord-006870-f5w6fw6q 1568 2 of of IN cord-006870-f5w6fw6q 1568 3 these these DT cord-006870-f5w6fw6q 1568 4 , , , cord-006870-f5w6fw6q 1568 5 47 47 CD cord-006870-f5w6fw6q 1568 6 required require VBN cord-006870-f5w6fw6q 1568 7 ICU ICU NNP cord-006870-f5w6fw6q 1568 8 management management NN cord-006870-f5w6fw6q 1568 9 , , , cord-006870-f5w6fw6q 1568 10 representing represent VBG cord-006870-f5w6fw6q 1568 11 1 1 CD cord-006870-f5w6fw6q 1568 12 % % NN cord-006870-f5w6fw6q 1568 13 of of IN cord-006870-f5w6fw6q 1568 14 the the DT cord-006870-f5w6fw6q 1568 15 total total JJ cord-006870-f5w6fw6q 1568 16 4687 4687 CD cord-006870-f5w6fw6q 1568 17 ICU ICU NNP cord-006870-f5w6fw6q 1568 18 admissions admission NNS cord-006870-f5w6fw6q 1568 19 during during IN cord-006870-f5w6fw6q 1568 20 this this DT cord-006870-f5w6fw6q 1568 21 time time NN cord-006870-f5w6fw6q 1568 22 frame frame NN cord-006870-f5w6fw6q 1568 23 . . . cord-006870-f5w6fw6q 1569 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1569 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1569 3 ( ( -LRB- cord-006870-f5w6fw6q 1569 4 ICH ICH NNP cord-006870-f5w6fw6q 1569 5 ) ) -RRB- cord-006870-f5w6fw6q 1569 6 was be VBD cord-006870-f5w6fw6q 1569 7 present present JJ cord-006870-f5w6fw6q 1569 8 in in IN cord-006870-f5w6fw6q 1569 9 32 32 CD cord-006870-f5w6fw6q 1569 10 patients patient NNS cord-006870-f5w6fw6q 1569 11 while while IN cord-006870-f5w6fw6q 1569 12 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 1569 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1569 14 ( ( -LRB- cord-006870-f5w6fw6q 1569 15 SAH SAH NNP cord-006870-f5w6fw6q 1569 16 ) ) -RRB- cord-006870-f5w6fw6q 1569 17 was be VBD cord-006870-f5w6fw6q 1569 18 seen see VBN cord-006870-f5w6fw6q 1569 19 in in IN cord-006870-f5w6fw6q 1569 20 15 15 CD cord-006870-f5w6fw6q 1569 21 . . . cord-006870-f5w6fw6q 1570 1 The the DT cord-006870-f5w6fw6q 1570 2 latter latter JJ cord-006870-f5w6fw6q 1570 3 had have VBD cord-006870-f5w6fw6q 1570 4 a a DT cord-006870-f5w6fw6q 1570 5 median median JJ cord-006870-f5w6fw6q 1570 6 Fisher Fisher NNP cord-006870-f5w6fw6q 1570 7 score score NN cord-006870-f5w6fw6q 1570 8 of of IN cord-006870-f5w6fw6q 1570 9 4 4 CD cord-006870-f5w6fw6q 1570 10 . . . cord-006870-f5w6fw6q 1571 1 For for IN cord-006870-f5w6fw6q 1571 2 all all DT cord-006870-f5w6fw6q 1571 3 patients patient NNS cord-006870-f5w6fw6q 1571 4 , , , cord-006870-f5w6fw6q 1571 5 the the DT cord-006870-f5w6fw6q 1571 6 most most RBS cord-006870-f5w6fw6q 1571 7 common common JJ cord-006870-f5w6fw6q 1571 8 risk risk NN cord-006870-f5w6fw6q 1571 9 factors factor NNS cord-006870-f5w6fw6q 1571 10 were be VBD cord-006870-f5w6fw6q 1571 11 hypertension hypertension NN cord-006870-f5w6fw6q 1571 12 ( ( -LRB- cord-006870-f5w6fw6q 1571 13 61.7 61.7 CD cord-006870-f5w6fw6q 1571 14 % % NN cord-006870-f5w6fw6q 1571 15 ) ) -RRB- cord-006870-f5w6fw6q 1571 16 , , , cord-006870-f5w6fw6q 1571 17 dyslipidemia dyslipidemia NN cord-006870-f5w6fw6q 1571 18 ( ( -LRB- cord-006870-f5w6fw6q 1571 19 29.8 29.8 CD cord-006870-f5w6fw6q 1571 20 % % NN cord-006870-f5w6fw6q 1571 21 ) ) -RRB- cord-006870-f5w6fw6q 1571 22 and and CC cord-006870-f5w6fw6q 1571 23 smoking smoking NN cord-006870-f5w6fw6q 1571 24 ( ( -LRB- cord-006870-f5w6fw6q 1571 25 17.0 17.0 CD cord-006870-f5w6fw6q 1571 26 % % NN cord-006870-f5w6fw6q 1571 27 ) ) -RRB- cord-006870-f5w6fw6q 1571 28 . . . cord-006870-f5w6fw6q 1572 1 ICU ICU NNP cord-006870-f5w6fw6q 1572 2 mortality mortality NN cord-006870-f5w6fw6q 1572 3 was be VBD cord-006870-f5w6fw6q 1572 4 25.5 25.5 CD cord-006870-f5w6fw6q 1572 5 % % NN cord-006870-f5w6fw6q 1572 6 ( ( -LRB- cord-006870-f5w6fw6q 1572 7 53.3 53.3 CD cord-006870-f5w6fw6q 1572 8 % % NN cord-006870-f5w6fw6q 1572 9 with with IN cord-006870-f5w6fw6q 1572 10 ICH ICH NNP cord-006870-f5w6fw6q 1572 11 and and CC cord-006870-f5w6fw6q 1572 12 12.5 12.5 CD cord-006870-f5w6fw6q 1572 13 % % NN cord-006870-f5w6fw6q 1572 14 with with IN cord-006870-f5w6fw6q 1572 15 SAH SAH NNP cord-006870-f5w6fw6q 1572 16 ) ) -RRB- cord-006870-f5w6fw6q 1572 17 . . . cord-006870-f5w6fw6q 1573 1 Mean mean JJ cord-006870-f5w6fw6q 1573 2 Sequential Sequential NNP cord-006870-f5w6fw6q 1573 3 Organ Organ NNP cord-006870-f5w6fw6q 1573 4 Failure Failure NNP cord-006870-f5w6fw6q 1573 5 Assessment Assessment NNP cord-006870-f5w6fw6q 1573 6 ( ( -LRB- cord-006870-f5w6fw6q 1573 7 SOFA SOFA NNP cord-006870-f5w6fw6q 1573 8 ) ) -RRB- cord-006870-f5w6fw6q 1573 9 score score NN cord-006870-f5w6fw6q 1573 10 was be VBD cord-006870-f5w6fw6q 1573 11 significantly significantly RB cord-006870-f5w6fw6q 1573 12 greater great JJR cord-006870-f5w6fw6q 1573 13 in in IN cord-006870-f5w6fw6q 1573 14 patients patient NNS cord-006870-f5w6fw6q 1573 15 who who WP cord-006870-f5w6fw6q 1573 16 died die VBD cord-006870-f5w6fw6q 1573 17 ( ( -LRB- cord-006870-f5w6fw6q 1573 18 8.8 8.8 CD cord-006870-f5w6fw6q 1573 19 vs. vs. IN cord-006870-f5w6fw6q 1573 20 1.8 1.8 CD cord-006870-f5w6fw6q 1573 21 , , , cord-006870-f5w6fw6q 1573 22 p<0.05 p<0.05 CD cord-006870-f5w6fw6q 1573 23 ) ) -RRB- cord-006870-f5w6fw6q 1573 24 and and CC cord-006870-f5w6fw6q 1573 25 mean mean VB cord-006870-f5w6fw6q 1573 26 Glasgow Glasgow NNP cord-006870-f5w6fw6q 1573 27 Coma Coma NNP cord-006870-f5w6fw6q 1573 28 Scale Scale NNP cord-006870-f5w6fw6q 1573 29 was be VBD cord-006870-f5w6fw6q 1573 30 significantly significantly RB cord-006870-f5w6fw6q 1573 31 lower low JJR cord-006870-f5w6fw6q 1573 32 ( ( -LRB- cord-006870-f5w6fw6q 1573 33 8.1 8.1 CD cord-006870-f5w6fw6q 1573 34 vs. vs. IN cord-006870-f5w6fw6q 1573 35 13.2 13.2 CD cord-006870-f5w6fw6q 1573 36 , , , cord-006870-f5w6fw6q 1573 37 p<0.05 p<0.05 CD cord-006870-f5w6fw6q 1573 38 ) ) -RRB- cord-006870-f5w6fw6q 1573 39 . . . cord-006870-f5w6fw6q 1574 1 Vasopressors vasopressor NNS cord-006870-f5w6fw6q 1574 2 were be VBD cord-006870-f5w6fw6q 1574 3 required require VBN cord-006870-f5w6fw6q 1574 4 in in IN cord-006870-f5w6fw6q 1574 5 18 18 CD cord-006870-f5w6fw6q 1574 6 patients patient NNS cord-006870-f5w6fw6q 1574 7 ( ( -LRB- cord-006870-f5w6fw6q 1574 8 38.3 38.3 CD cord-006870-f5w6fw6q 1574 9 % % NN cord-006870-f5w6fw6q 1574 10 ) ) -RRB- cord-006870-f5w6fw6q 1574 11 , , , cord-006870-f5w6fw6q 1574 12 mechanical mechanical JJ cord-006870-f5w6fw6q 1574 13 ventilation ventilation NN cord-006870-f5w6fw6q 1574 14 in in IN cord-006870-f5w6fw6q 1574 15 22 22 CD cord-006870-f5w6fw6q 1574 16 ( ( -LRB- cord-006870-f5w6fw6q 1574 17 46.8 46.8 CD cord-006870-f5w6fw6q 1574 18 % % NN cord-006870-f5w6fw6q 1574 19 ) ) -RRB- cord-006870-f5w6fw6q 1574 20 , , , cord-006870-f5w6fw6q 1574 21 and and CC cord-006870-f5w6fw6q 1574 22 half half NN cord-006870-f5w6fw6q 1574 23 of of IN cord-006870-f5w6fw6q 1574 24 the the DT cord-006870-f5w6fw6q 1574 25 patients patient NNS cord-006870-f5w6fw6q 1574 26 requiring require VBG cord-006870-f5w6fw6q 1574 27 either either CC cord-006870-f5w6fw6q 1574 28 support support NN cord-006870-f5w6fw6q 1574 29 therapy therapy NN cord-006870-f5w6fw6q 1574 30 died die VBD cord-006870-f5w6fw6q 1574 31 . . . cord-006870-f5w6fw6q 1575 1 Only only RB cord-006870-f5w6fw6q 1575 2 5 5 CD cord-006870-f5w6fw6q 1575 3 patients patient NNS cord-006870-f5w6fw6q 1575 4 ( ( -LRB- cord-006870-f5w6fw6q 1575 5 10.6 10.6 CD cord-006870-f5w6fw6q 1575 6 % % NN cord-006870-f5w6fw6q 1575 7 ) ) -RRB- cord-006870-f5w6fw6q 1575 8 had have VBD cord-006870-f5w6fw6q 1575 9 fever fever NN cord-006870-f5w6fw6q 1575 10 in in IN cord-006870-f5w6fw6q 1575 11 the the DT cord-006870-f5w6fw6q 1575 12 first first JJ cord-006870-f5w6fw6q 1575 13 48 48 CD cord-006870-f5w6fw6q 1575 14 hours hour NNS cord-006870-f5w6fw6q 1575 15 and and CC cord-006870-f5w6fw6q 1575 16 all all DT cord-006870-f5w6fw6q 1575 17 died die VBD cord-006870-f5w6fw6q 1575 18 . . . cord-006870-f5w6fw6q 1576 1 Mean mean JJ cord-006870-f5w6fw6q 1576 2 coefficient coefficient NN cord-006870-f5w6fw6q 1576 3 of of IN cord-006870-f5w6fw6q 1576 4 variation variation NN cord-006870-f5w6fw6q 1576 5 for for IN cord-006870-f5w6fw6q 1576 6 systolic systolic JJ cord-006870-f5w6fw6q 1576 7 , , . cord-006870-f5w6fw6q 1577 1 diastolic diastolic JJ cord-006870-f5w6fw6q 1577 2 and and CC cord-006870-f5w6fw6q 1577 3 mean mean VB cord-006870-f5w6fw6q 1577 4 blood blood NN cord-006870-f5w6fw6q 1577 5 pressure pressure NN cord-006870-f5w6fw6q 1577 6 was be VBD cord-006870-f5w6fw6q 1577 7 significantly significantly RB cord-006870-f5w6fw6q 1577 8 lower low JJR cord-006870-f5w6fw6q 1577 9 in in IN cord-006870-f5w6fw6q 1577 10 patients patient NNS cord-006870-f5w6fw6q 1577 11 who who WP cord-006870-f5w6fw6q 1577 12 survived survive VBD cord-006870-f5w6fw6q 1577 13 . . . cord-006870-f5w6fw6q 1578 1 Mortality mortality NN cord-006870-f5w6fw6q 1578 2 cases case NNS cord-006870-f5w6fw6q 1578 3 were be VBD cord-006870-f5w6fw6q 1578 4 more more RBR cord-006870-f5w6fw6q 1578 5 likely likely JJ cord-006870-f5w6fw6q 1578 6 to to TO cord-006870-f5w6fw6q 1578 7 have have VB cord-006870-f5w6fw6q 1578 8 hypokalemia hypokalemia NN cord-006870-f5w6fw6q 1578 9 and and CC cord-006870-f5w6fw6q 1578 10 hypomagnesemia hypomagnesemia NN cord-006870-f5w6fw6q 1578 11 than than IN cord-006870-f5w6fw6q 1578 12 surviving survive VBG cord-006870-f5w6fw6q 1578 13 patients patient NNS cord-006870-f5w6fw6q 1578 14 ( ( -LRB- cord-006870-f5w6fw6q 1578 15 50.0 50.0 CD cord-006870-f5w6fw6q 1578 16 % % NN cord-006870-f5w6fw6q 1578 17 vs. vs. CC cord-006870-f5w6fw6q 1578 18 25.7 25.7 CD cord-006870-f5w6fw6q 1578 19 % % NN cord-006870-f5w6fw6q 1578 20 and and CC cord-006870-f5w6fw6q 1578 21 58.33 58.33 CD cord-006870-f5w6fw6q 1578 22 % % NN cord-006870-f5w6fw6q 1578 23 vs. vs. IN cord-006870-f5w6fw6q 1578 24 40 40 CD cord-006870-f5w6fw6q 1578 25 % % NN cord-006870-f5w6fw6q 1578 26 , , , cord-006870-f5w6fw6q 1578 27 respectively respectively RB cord-006870-f5w6fw6q 1578 28 ) ) -RRB- cord-006870-f5w6fw6q 1578 29 . . . cord-006870-f5w6fw6q 1579 1 ICU ICU NNP cord-006870-f5w6fw6q 1579 2 - - HYPH cord-006870-f5w6fw6q 1579 3 admitted admit VBN cord-006870-f5w6fw6q 1579 4 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1579 5 stroke stroke NN cord-006870-f5w6fw6q 1579 6 patients patient NNS cord-006870-f5w6fw6q 1579 7 have have VBP cord-006870-f5w6fw6q 1579 8 a a DT cord-006870-f5w6fw6q 1579 9 poor poor JJ cord-006870-f5w6fw6q 1579 10 prognosis prognosis NN cord-006870-f5w6fw6q 1579 11 . . . cord-006870-f5w6fw6q 1580 1 SOFA SOFA NNP cord-006870-f5w6fw6q 1580 2 and and CC cord-006870-f5w6fw6q 1580 3 GCS GCS NNP cord-006870-f5w6fw6q 1580 4 are be VBP cord-006870-f5w6fw6q 1580 5 accurate accurate JJ cord-006870-f5w6fw6q 1580 6 predictors predictor NNS cord-006870-f5w6fw6q 1580 7 of of IN cord-006870-f5w6fw6q 1580 8 mortality mortality NN cord-006870-f5w6fw6q 1580 9 . . . cord-006870-f5w6fw6q 1581 1 Certain certain JJ cord-006870-f5w6fw6q 1581 2 electrolyte electrolyte JJ cord-006870-f5w6fw6q 1581 3 disturbances disturbance NNS cord-006870-f5w6fw6q 1581 4 , , , cord-006870-f5w6fw6q 1581 5 fever fever NN cord-006870-f5w6fw6q 1581 6 and and CC cord-006870-f5w6fw6q 1581 7 a a DT cord-006870-f5w6fw6q 1581 8 higher high JJR cord-006870-f5w6fw6q 1581 9 variation variation NN cord-006870-f5w6fw6q 1581 10 of of IN cord-006870-f5w6fw6q 1581 11 blood blood NN cord-006870-f5w6fw6q 1581 12 pressure pressure NN cord-006870-f5w6fw6q 1581 13 during during IN cord-006870-f5w6fw6q 1581 14 the the DT cord-006870-f5w6fw6q 1581 15 first first JJ cord-006870-f5w6fw6q 1581 16 48 48 CD cord-006870-f5w6fw6q 1581 17 hours hour NNS cord-006870-f5w6fw6q 1581 18 were be VBD cord-006870-f5w6fw6q 1581 19 associated associate VBN cord-006870-f5w6fw6q 1581 20 with with IN cord-006870-f5w6fw6q 1581 21 a a DT cord-006870-f5w6fw6q 1581 22 worse bad JJR cord-006870-f5w6fw6q 1581 23 outcome outcome NN cord-006870-f5w6fw6q 1581 24 . . . cord-006870-f5w6fw6q 1582 1 The the DT cord-006870-f5w6fw6q 1582 2 association association NN cord-006870-f5w6fw6q 1582 3 between between IN cord-006870-f5w6fw6q 1582 4 worsening worsen VBG cord-006870-f5w6fw6q 1582 5 cerebral cerebral JJ cord-006870-f5w6fw6q 1582 6 edema edema NN cord-006870-f5w6fw6q 1582 7 and and CC cord-006870-f5w6fw6q 1582 8 unfavorable unfavorable JJ cord-006870-f5w6fw6q 1582 9 outcome outcome NN cord-006870-f5w6fw6q 1582 10 in in IN cord-006870-f5w6fw6q 1582 11 ICH ICH NNP cord-006870-f5w6fw6q 1582 12 patients patient NNS cord-006870-f5w6fw6q 1582 13 has have VBZ cord-006870-f5w6fw6q 1582 14 been be VBN cord-006870-f5w6fw6q 1582 15 described describe VBN cord-006870-f5w6fw6q 1582 16 in in IN cord-006870-f5w6fw6q 1582 17 RCTs rct NNS cord-006870-f5w6fw6q 1582 18 . . . cord-006870-f5w6fw6q 1583 1 The the DT cord-006870-f5w6fw6q 1583 2 objective objective NN cord-006870-f5w6fw6q 1583 3 of of IN cord-006870-f5w6fw6q 1583 4 this this DT cord-006870-f5w6fw6q 1583 5 analysis analysis NN cord-006870-f5w6fw6q 1583 6 was be VBD cord-006870-f5w6fw6q 1583 7 to to TO cord-006870-f5w6fw6q 1583 8 compare compare VB cord-006870-f5w6fw6q 1583 9 hospitalized hospitalize VBN cord-006870-f5w6fw6q 1583 10 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1583 11 ICH ICH NNP cord-006870-f5w6fw6q 1583 12 patients patient NNS cord-006870-f5w6fw6q 1583 13 with with IN cord-006870-f5w6fw6q 1583 14 and and CC cord-006870-f5w6fw6q 1583 15 without without IN cord-006870-f5w6fw6q 1583 16 perihematomal perihematomal JJ cord-006870-f5w6fw6q 1583 17 edema edema NN cord-006870-f5w6fw6q 1583 18 ( ( -LRB- cord-006870-f5w6fw6q 1583 19 PHE PHE NNP cord-006870-f5w6fw6q 1583 20 ) ) -RRB- cord-006870-f5w6fw6q 1583 21 expansion expansion NN cord-006870-f5w6fw6q 1583 22 and and CC cord-006870-f5w6fw6q 1583 23 to to TO cord-006870-f5w6fw6q 1583 24 evaluate evaluate VB cord-006870-f5w6fw6q 1583 25 relationships relationship NNS cord-006870-f5w6fw6q 1583 26 between between IN cord-006870-f5w6fw6q 1583 27 hypertonic hypertonic JJ cord-006870-f5w6fw6q 1583 28 saline saline NN cord-006870-f5w6fw6q 1583 29 ( ( -LRB- cord-006870-f5w6fw6q 1583 30 HTS HTS NNP cord-006870-f5w6fw6q 1583 31 ) ) -RRB- cord-006870-f5w6fw6q 1583 32 use use VBP cord-006870-f5w6fw6q 1583 33 , , , cord-006870-f5w6fw6q 1583 34 peak peak NN cord-006870-f5w6fw6q 1583 35 serum serum NN cord-006870-f5w6fw6q 1583 36 Na Na NNP cord-006870-f5w6fw6q 1583 37 , , , cord-006870-f5w6fw6q 1583 38 PHE PHE NNP cord-006870-f5w6fw6q 1583 39 expansion expansion NN cord-006870-f5w6fw6q 1583 40 , , , cord-006870-f5w6fw6q 1583 41 and and CC cord-006870-f5w6fw6q 1583 42 short short JJ cord-006870-f5w6fw6q 1583 43 - - HYPH cord-006870-f5w6fw6q 1583 44 term term NN cord-006870-f5w6fw6q 1583 45 outcomes outcome NNS cord-006870-f5w6fw6q 1583 46 . . . cord-006870-f5w6fw6q 1584 1 We -PRON- PRP cord-006870-f5w6fw6q 1584 2 conducted conduct VBD cord-006870-f5w6fw6q 1584 3 a a DT cord-006870-f5w6fw6q 1584 4 cross cross JJ cord-006870-f5w6fw6q 1584 5 - - JJ cord-006870-f5w6fw6q 1584 6 sectional sectional JJ cord-006870-f5w6fw6q 1584 7 study study NN cord-006870-f5w6fw6q 1584 8 of of IN cord-006870-f5w6fw6q 1584 9 consecutive consecutive JJ cord-006870-f5w6fw6q 1584 10 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1584 11 ICH ICH NNP cord-006870-f5w6fw6q 1584 12 patients patient NNS cord-006870-f5w6fw6q 1584 13 admitted admit VBD cord-006870-f5w6fw6q 1584 14 to to IN cord-006870-f5w6fw6q 1584 15 a a DT cord-006870-f5w6fw6q 1584 16 single single JJ cord-006870-f5w6fw6q 1584 17 center center NN cord-006870-f5w6fw6q 1584 18 from from IN cord-006870-f5w6fw6q 1584 19 11/2014 11/2014 NNS cord-006870-f5w6fw6q 1584 20 - - SYM cord-006870-f5w6fw6q 1584 21 11/2015 11/2015 CD cord-006870-f5w6fw6q 1584 22 . . . cord-006870-f5w6fw6q 1585 1 Head Head NNP cord-006870-f5w6fw6q 1585 2 CTs ct NNS cord-006870-f5w6fw6q 1585 3 during during IN cord-006870-f5w6fw6q 1585 4 the the DT cord-006870-f5w6fw6q 1585 5 first first JJ cord-006870-f5w6fw6q 1585 6 week week NN cord-006870-f5w6fw6q 1585 7 of of IN cord-006870-f5w6fw6q 1585 8 admission admission NN cord-006870-f5w6fw6q 1585 9 , , , cord-006870-f5w6fw6q 1585 10 use use NN cord-006870-f5w6fw6q 1585 11 of of IN cord-006870-f5w6fw6q 1585 12 HTS HTS NNP cord-006870-f5w6fw6q 1585 13 , , , cord-006870-f5w6fw6q 1585 14 and and CC cord-006870-f5w6fw6q 1585 15 PHE PHE NNP cord-006870-f5w6fw6q 1585 16 ( ( -LRB- cord-006870-f5w6fw6q 1585 17 using use VBG cord-006870-f5w6fw6q 1585 18 ABC/2 ABC/2 NNP cord-006870-f5w6fw6q 1585 19 method method NN cord-006870-f5w6fw6q 1585 20 ) ) -RRB- cord-006870-f5w6fw6q 1585 21 were be VBD cord-006870-f5w6fw6q 1585 22 evaluated evaluate VBN cord-006870-f5w6fw6q 1585 23 . . . cord-006870-f5w6fw6q 1586 1 PHE PHE NNP cord-006870-f5w6fw6q 1586 2 expansion expansion NN cord-006870-f5w6fw6q 1586 3 of of IN cord-006870-f5w6fw6q 1586 4 10 10 CD cord-006870-f5w6fw6q 1586 5 % % NN cord-006870-f5w6fw6q 1586 6 or or CC cord-006870-f5w6fw6q 1586 7 more more JJR cord-006870-f5w6fw6q 1586 8 was be VBD cord-006870-f5w6fw6q 1586 9 considered consider VBN cord-006870-f5w6fw6q 1586 10 worsening worsen VBG cord-006870-f5w6fw6q 1586 11 edema edema NN cord-006870-f5w6fw6q 1586 12 . . . cord-006870-f5w6fw6q 1587 1 Outcomes outcome NNS cord-006870-f5w6fw6q 1587 2 of of IN cord-006870-f5w6fw6q 1587 3 interest interest NN cord-006870-f5w6fw6q 1587 4 included include VBD cord-006870-f5w6fw6q 1587 5 time time NN cord-006870-f5w6fw6q 1587 6 to to TO cord-006870-f5w6fw6q 1587 7 peak peak VB cord-006870-f5w6fw6q 1587 8 Na Na NNP cord-006870-f5w6fw6q 1587 9 , , , cord-006870-f5w6fw6q 1587 10 poor poor JJ cord-006870-f5w6fw6q 1587 11 disposition disposition NN cord-006870-f5w6fw6q 1587 12 ( ( -LRB- cord-006870-f5w6fw6q 1587 13 not not RB cord-006870-f5w6fw6q 1587 14 home home NN cord-006870-f5w6fw6q 1587 15 or or CC cord-006870-f5w6fw6q 1587 16 inpatient inpatient JJ cord-006870-f5w6fw6q 1587 17 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 1587 18 ) ) -RRB- cord-006870-f5w6fw6q 1587 19 , , , cord-006870-f5w6fw6q 1587 20 discharge discharge NN cord-006870-f5w6fw6q 1587 21 mRS mrs PRP$ cord-006870-f5w6fw6q 1587 22 4 4 CD cord-006870-f5w6fw6q 1587 23 - - SYM cord-006870-f5w6fw6q 1587 24 6 6 CD cord-006870-f5w6fw6q 1587 25 , , , cord-006870-f5w6fw6q 1587 26 and and CC cord-006870-f5w6fw6q 1587 27 in in IN cord-006870-f5w6fw6q 1587 28 - - HYPH cord-006870-f5w6fw6q 1587 29 hospital hospital NN cord-006870-f5w6fw6q 1587 30 death death NN cord-006870-f5w6fw6q 1587 31 . . . cord-006870-f5w6fw6q 1588 1 Of of IN cord-006870-f5w6fw6q 1588 2 180 180 CD cord-006870-f5w6fw6q 1588 3 ICH ICH NNP cord-006870-f5w6fw6q 1588 4 patients patient NNS cord-006870-f5w6fw6q 1588 5 , , , cord-006870-f5w6fw6q 1588 6 43 43 CD cord-006870-f5w6fw6q 1588 7 % % NN cord-006870-f5w6fw6q 1588 8 experienced experience VBD cord-006870-f5w6fw6q 1588 9 worsening worsen VBG cord-006870-f5w6fw6q 1588 10 PHE PHE NNP cord-006870-f5w6fw6q 1588 11 . . . cord-006870-f5w6fw6q 1589 1 There there EX cord-006870-f5w6fw6q 1589 2 was be VBD cord-006870-f5w6fw6q 1589 3 no no DT cord-006870-f5w6fw6q 1589 4 difference difference NN cord-006870-f5w6fw6q 1589 5 in in IN cord-006870-f5w6fw6q 1589 6 age age NN cord-006870-f5w6fw6q 1589 7 , , , cord-006870-f5w6fw6q 1589 8 race race NN cord-006870-f5w6fw6q 1589 9 , , , cord-006870-f5w6fw6q 1589 10 sex sex NN cord-006870-f5w6fw6q 1589 11 , , , cord-006870-f5w6fw6q 1589 12 arrival arrival NN cord-006870-f5w6fw6q 1589 13 BP BP NNP cord-006870-f5w6fw6q 1589 14 arrival arrival NN cord-006870-f5w6fw6q 1589 15 , , , cord-006870-f5w6fw6q 1589 16 or or CC cord-006870-f5w6fw6q 1589 17 vascular vascular JJ cord-006870-f5w6fw6q 1589 18 risk risk NN cord-006870-f5w6fw6q 1589 19 factors factor NNS cord-006870-f5w6fw6q 1589 20 in in IN cord-006870-f5w6fw6q 1589 21 patients patient NNS cord-006870-f5w6fw6q 1589 22 with with IN cord-006870-f5w6fw6q 1589 23 or or CC cord-006870-f5w6fw6q 1589 24 without without IN cord-006870-f5w6fw6q 1589 25 worsening worsen VBG cord-006870-f5w6fw6q 1589 26 PHE PHE NNP cord-006870-f5w6fw6q 1589 27 . . . cord-006870-f5w6fw6q 1590 1 However however RB cord-006870-f5w6fw6q 1590 2 , , , cord-006870-f5w6fw6q 1590 3 for for IN cord-006870-f5w6fw6q 1590 4 each each DT cord-006870-f5w6fw6q 1590 5 mm mm NNP cord-006870-f5w6fw6q 1590 6 of of IN cord-006870-f5w6fw6q 1590 7 midline midline JJ cord-006870-f5w6fw6q 1590 8 shift shift NN cord-006870-f5w6fw6q 1590 9 ( ( -LRB- cord-006870-f5w6fw6q 1590 10 MLS MLS NNP cord-006870-f5w6fw6q 1590 11 ) ) -RRB- cord-006870-f5w6fw6q 1590 12 present present JJ cord-006870-f5w6fw6q 1590 13 on on IN cord-006870-f5w6fw6q 1590 14 initial initial JJ cord-006870-f5w6fw6q 1590 15 head head NN cord-006870-f5w6fw6q 1590 16 CT CT NNP cord-006870-f5w6fw6q 1590 17 , , , cord-006870-f5w6fw6q 1590 18 odds odd NNS cord-006870-f5w6fw6q 1590 19 of of IN cord-006870-f5w6fw6q 1590 20 PHE PHE NNP cord-006870-f5w6fw6q 1590 21 expansion expansion NN cord-006870-f5w6fw6q 1590 22 was be VBD cord-006870-f5w6fw6q 1590 23 decreased decrease VBN cord-006870-f5w6fw6q 1590 24 by by IN cord-006870-f5w6fw6q 1590 25 16 16 CD cord-006870-f5w6fw6q 1590 26 % % NN cord-006870-f5w6fw6q 1590 27 ( ( -LRB- cord-006870-f5w6fw6q 1590 28 OR or CC cord-006870-f5w6fw6q 1590 29 0.84 0.84 CD cord-006870-f5w6fw6q 1590 30 , , , cord-006870-f5w6fw6q 1590 31 95%CI 95%ci CD cord-006870-f5w6fw6q 1590 32 0.73 0.73 CD cord-006870-f5w6fw6q 1590 33 - - HYPH cord-006870-f5w6fw6q 1590 34 0.97 0.97 CD cord-006870-f5w6fw6q 1590 35 , , , cord-006870-f5w6fw6q 1590 36 p=0.014 p=0.014 NNS cord-006870-f5w6fw6q 1590 37 ) ) -RRB- cord-006870-f5w6fw6q 1590 38 . . . cord-006870-f5w6fw6q 1591 1 MLS MLS NNP cord-006870-f5w6fw6q 1591 2 on on IN cord-006870-f5w6fw6q 1591 3 initial initial JJ cord-006870-f5w6fw6q 1591 4 head head NN cord-006870-f5w6fw6q 1592 1 CT CT NNP cord-006870-f5w6fw6q 1592 2 was be VBD cord-006870-f5w6fw6q 1592 3 the the DT cord-006870-f5w6fw6q 1592 4 best good JJS cord-006870-f5w6fw6q 1592 5 discriminator discriminator NN cord-006870-f5w6fw6q 1592 6 of of IN cord-006870-f5w6fw6q 1592 7 PHE PHE NNP cord-006870-f5w6fw6q 1592 8 expansion expansion NN cord-006870-f5w6fw6q 1592 9 ( ( -LRB- cord-006870-f5w6fw6q 1592 10 AUC AUC NNP cord-006870-f5w6fw6q 1592 11 0.811 0.811 CD cord-006870-f5w6fw6q 1593 1 ( ( -LRB- cord-006870-f5w6fw6q 1593 2 95%CI 95%ci CD cord-006870-f5w6fw6q 1593 3 0.663 0.663 CD cord-006870-f5w6fw6q 1593 4 - - HYPH cord-006870-f5w6fw6q 1593 5 0.958 0.958 CD cord-006870-f5w6fw6q 1593 6 ) ) -RRB- cord-006870-f5w6fw6q 1593 7 . . . cord-006870-f5w6fw6q 1594 1 Although although IN cord-006870-f5w6fw6q 1594 2 hampered hamper VBN cord-006870-f5w6fw6q 1594 3 by by IN cord-006870-f5w6fw6q 1594 4 small small JJ cord-006870-f5w6fw6q 1594 5 sample sample NN cord-006870-f5w6fw6q 1594 6 size size NN cord-006870-f5w6fw6q 1594 7 , , , cord-006870-f5w6fw6q 1594 8 our -PRON- PRP$ cord-006870-f5w6fw6q 1594 9 data data NN cord-006870-f5w6fw6q 1594 10 indicates indicate VBZ cord-006870-f5w6fw6q 1594 11 that that IN cord-006870-f5w6fw6q 1594 12 finding find VBG cord-006870-f5w6fw6q 1594 13 that that IN cord-006870-f5w6fw6q 1594 14 ICH ICH NNP cord-006870-f5w6fw6q 1594 15 patients patient NNS cord-006870-f5w6fw6q 1594 16 with with IN cord-006870-f5w6fw6q 1594 17 degree degree NN cord-006870-f5w6fw6q 1594 18 of of IN cord-006870-f5w6fw6q 1594 19 MLS MLS NNP cord-006870-f5w6fw6q 1594 20 on on IN cord-006870-f5w6fw6q 1594 21 initial initial JJ cord-006870-f5w6fw6q 1594 22 head head NN cord-006870-f5w6fw6q 1594 23 CT CT NNP cord-006870-f5w6fw6q 1594 24 is be VBZ cord-006870-f5w6fw6q 1594 25 the the DT cord-006870-f5w6fw6q 1594 26 best good JJS cord-006870-f5w6fw6q 1594 27 radiographic radiographic JJ cord-006870-f5w6fw6q 1594 28 predictor predictor NN cord-006870-f5w6fw6q 1594 29 of of IN cord-006870-f5w6fw6q 1594 30 had have VBD cord-006870-f5w6fw6q 1594 31 lower low JJR cord-006870-f5w6fw6q 1594 32 odds odd NNS cord-006870-f5w6fw6q 1594 33 of of IN cord-006870-f5w6fw6q 1594 34 PHE PHE NNP cord-006870-f5w6fw6q 1594 35 expansion expansion NN cord-006870-f5w6fw6q 1594 36 . . . cord-006870-f5w6fw6q 1595 1 Those those DT cord-006870-f5w6fw6q 1595 2 without without IN cord-006870-f5w6fw6q 1595 3 MLS MLS NNP cord-006870-f5w6fw6q 1595 4 at at IN cord-006870-f5w6fw6q 1595 5 presentation presentation NN cord-006870-f5w6fw6q 1595 6 may may MD cord-006870-f5w6fw6q 1595 7 be be VB cord-006870-f5w6fw6q 1595 8 at at IN cord-006870-f5w6fw6q 1595 9 risk risk NN cord-006870-f5w6fw6q 1595 10 of of IN cord-006870-f5w6fw6q 1595 11 PHE PHE NNP cord-006870-f5w6fw6q 1595 12 expansion expansion NN cord-006870-f5w6fw6q 1595 13 , , , cord-006870-f5w6fw6q 1595 14 and and CC cord-006870-f5w6fw6q 1595 15 counterintuitively counterintuitively RB cord-006870-f5w6fw6q 1595 16 may may MD cord-006870-f5w6fw6q 1595 17 be be VB cord-006870-f5w6fw6q 1595 18 those those DT cord-006870-f5w6fw6q 1595 19 most most RBS cord-006870-f5w6fw6q 1595 20 in in IN cord-006870-f5w6fw6q 1595 21 need need NN cord-006870-f5w6fw6q 1595 22 of of IN cord-006870-f5w6fw6q 1595 23 aggressive aggressive JJ cord-006870-f5w6fw6q 1595 24 medical medical JJ cord-006870-f5w6fw6q 1595 25 management management NN cord-006870-f5w6fw6q 1595 26 . . . cord-006870-f5w6fw6q 1596 1 may may MD cord-006870-f5w6fw6q 1596 2 suggest suggest VB cord-006870-f5w6fw6q 1596 3 a a DT cord-006870-f5w6fw6q 1596 4 role role NN cord-006870-f5w6fw6q 1596 5 for for IN cord-006870-f5w6fw6q 1596 6 intensive intensive JJ cord-006870-f5w6fw6q 1596 7 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 1596 8 in in IN cord-006870-f5w6fw6q 1596 9 patients patient NNS cord-006870-f5w6fw6q 1596 10 with with IN cord-006870-f5w6fw6q 1596 11 favorable favorable JJ cord-006870-f5w6fw6q 1596 12 imaging imaging NN cord-006870-f5w6fw6q 1596 13 at at IN cord-006870-f5w6fw6q 1596 14 presentation presentation NN cord-006870-f5w6fw6q 1596 15 . . . cord-006870-f5w6fw6q 1597 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1597 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1597 3 ( ( -LRB- cord-006870-f5w6fw6q 1597 4 ICH ICH NNP cord-006870-f5w6fw6q 1597 5 ) ) -RRB- cord-006870-f5w6fw6q 1597 6 is be VBZ cord-006870-f5w6fw6q 1597 7 a a DT cord-006870-f5w6fw6q 1597 8 devastating devastating JJ cord-006870-f5w6fw6q 1597 9 stroke stroke NN cord-006870-f5w6fw6q 1597 10 with with IN cord-006870-f5w6fw6q 1597 11 high high JJ cord-006870-f5w6fw6q 1597 12 mortality mortality NN cord-006870-f5w6fw6q 1597 13 rates rate NNS cord-006870-f5w6fw6q 1597 14 . . . cord-006870-f5w6fw6q 1598 1 Previous previous JJ cord-006870-f5w6fw6q 1598 2 studies study NNS cord-006870-f5w6fw6q 1598 3 have have VBP cord-006870-f5w6fw6q 1598 4 shown show VBN cord-006870-f5w6fw6q 1598 5 a a DT cord-006870-f5w6fw6q 1598 6 potential potential JJ cord-006870-f5w6fw6q 1598 7 role role NN cord-006870-f5w6fw6q 1598 8 of of IN cord-006870-f5w6fw6q 1598 9 immune immune JJ cord-006870-f5w6fw6q 1598 10 cells cell NNS cord-006870-f5w6fw6q 1598 11 as as IN cord-006870-f5w6fw6q 1598 12 a a DT cord-006870-f5w6fw6q 1598 13 prognostication prognostication NN cord-006870-f5w6fw6q 1598 14 method method NN cord-006870-f5w6fw6q 1598 15 . . . cord-006870-f5w6fw6q 1599 1 A a DT cord-006870-f5w6fw6q 1599 2 high high JJ cord-006870-f5w6fw6q 1599 3 neutrophil neutrophil NN cord-006870-f5w6fw6q 1599 4 to to IN cord-006870-f5w6fw6q 1599 5 lymphocyte lymphocyte NN cord-006870-f5w6fw6q 1599 6 ratio ratio NN cord-006870-f5w6fw6q 1599 7 was be VBD cord-006870-f5w6fw6q 1599 8 associated associate VBN cord-006870-f5w6fw6q 1599 9 with with IN cord-006870-f5w6fw6q 1599 10 poor poor JJ cord-006870-f5w6fw6q 1599 11 outcomes outcome NNS cord-006870-f5w6fw6q 1599 12 after after IN cord-006870-f5w6fw6q 1599 13 ICH ICH NNP cord-006870-f5w6fw6q 1599 14 . . . cord-006870-f5w6fw6q 1600 1 We -PRON- PRP cord-006870-f5w6fw6q 1600 2 sought seek VBD cord-006870-f5w6fw6q 1600 3 to to TO cord-006870-f5w6fw6q 1600 4 determine determine VB cord-006870-f5w6fw6q 1600 5 whether whether IN cord-006870-f5w6fw6q 1600 6 absolute absolute JJ cord-006870-f5w6fw6q 1600 7 lymphocyte lymphocyte NN cord-006870-f5w6fw6q 1600 8 count(ALC count(alc NN cord-006870-f5w6fw6q 1600 9 ) ) -RRB- cord-006870-f5w6fw6q 1601 1 at at IN cord-006870-f5w6fw6q 1601 2 admission admission NN cord-006870-f5w6fw6q 1601 3 was be VBD cord-006870-f5w6fw6q 1601 4 predictive predictive JJ cord-006870-f5w6fw6q 1601 5 of of IN cord-006870-f5w6fw6q 1601 6 outcomes outcome NNS cord-006870-f5w6fw6q 1601 7 in in IN cord-006870-f5w6fw6q 1601 8 patients patient NNS cord-006870-f5w6fw6q 1601 9 with with IN cord-006870-f5w6fw6q 1601 10 ICH ICH NNP cord-006870-f5w6fw6q 1601 11 . . . cord-006870-f5w6fw6q 1602 1 We -PRON- PRP cord-006870-f5w6fw6q 1602 2 performed perform VBD cord-006870-f5w6fw6q 1602 3 a a DT cord-006870-f5w6fw6q 1602 4 retrospective retrospective JJ cord-006870-f5w6fw6q 1602 5 chart chart NN cord-006870-f5w6fw6q 1602 6 review review NN cord-006870-f5w6fw6q 1602 7 of of IN cord-006870-f5w6fw6q 1602 8 all all DT cord-006870-f5w6fw6q 1602 9 patients patient NNS cord-006870-f5w6fw6q 1602 10 admitted admit VBN cord-006870-f5w6fw6q 1602 11 to to IN cord-006870-f5w6fw6q 1602 12 our -PRON- PRP$ cord-006870-f5w6fw6q 1602 13 hospital hospital NN cord-006870-f5w6fw6q 1602 14 with with IN cord-006870-f5w6fw6q 1602 15 a a DT cord-006870-f5w6fw6q 1602 16 diagnosis diagnosis NN cord-006870-f5w6fw6q 1602 17 of of IN cord-006870-f5w6fw6q 1602 18 ICH ICH NNP cord-006870-f5w6fw6q 1602 19 from from IN cord-006870-f5w6fw6q 1602 20 January January NNP cord-006870-f5w6fw6q 1602 21 2012 2012 CD cord-006870-f5w6fw6q 1602 22 to to IN cord-006870-f5w6fw6q 1602 23 December December NNP cord-006870-f5w6fw6q 1602 24 2016.We 2016.we CD cord-006870-f5w6fw6q 1602 25 collected collect VBD cord-006870-f5w6fw6q 1602 26 baseline baseline JJ cord-006870-f5w6fw6q 1602 27 demographic demographic JJ cord-006870-f5w6fw6q 1602 28 characteristics characteristic NNS cord-006870-f5w6fw6q 1602 29 , , , cord-006870-f5w6fw6q 1602 30 medical medical JJ cord-006870-f5w6fw6q 1602 31 history history NN cord-006870-f5w6fw6q 1602 32 , , , cord-006870-f5w6fw6q 1602 33 ICH ICH NNP cord-006870-f5w6fw6q 1602 34 scores score NNS cord-006870-f5w6fw6q 1602 35 , , , cord-006870-f5w6fw6q 1602 36 differential differential JJ cord-006870-f5w6fw6q 1602 37 leucocyte leucocyte NNP cord-006870-f5w6fw6q 1602 38 , , , cord-006870-f5w6fw6q 1602 39 platelet platelet NN cord-006870-f5w6fw6q 1602 40 and and CC cord-006870-f5w6fw6q 1602 41 total total JJ cord-006870-f5w6fw6q 1602 42 leucocyte(TLC leucocyte(TLC NNP cord-006870-f5w6fw6q 1602 43 ) ) -RRB- cord-006870-f5w6fw6q 1602 44 counts count VBZ cord-006870-f5w6fw6q 1602 45 at at IN cord-006870-f5w6fw6q 1602 46 admission admission NN cord-006870-f5w6fw6q 1602 47 . . . cord-006870-f5w6fw6q 1603 1 The the DT cord-006870-f5w6fw6q 1603 2 functional functional JJ cord-006870-f5w6fw6q 1603 3 outcomes outcome NNS cord-006870-f5w6fw6q 1603 4 after after IN cord-006870-f5w6fw6q 1603 5 ICH ICH NNP cord-006870-f5w6fw6q 1603 6 were be VBD cord-006870-f5w6fw6q 1603 7 measured measure VBN cord-006870-f5w6fw6q 1603 8 using use VBG cord-006870-f5w6fw6q 1603 9 modified modify VBN cord-006870-f5w6fw6q 1603 10 rankin rankin NNP cord-006870-f5w6fw6q 1603 11 scale scale NN cord-006870-f5w6fw6q 1603 12 ( ( -LRB- cord-006870-f5w6fw6q 1603 13 MRS MRS NNP cord-006870-f5w6fw6q 1603 14 ) ) -RRB- cord-006870-f5w6fw6q 1603 15 at at IN cord-006870-f5w6fw6q 1603 16 discharge discharge NN cord-006870-f5w6fw6q 1603 17 . . . cord-006870-f5w6fw6q 1604 1 MRS MRS NNP cord-006870-f5w6fw6q 1604 2 of of IN cord-006870-f5w6fw6q 1604 3 5 5 CD cord-006870-f5w6fw6q 1604 4 and and CC cord-006870-f5w6fw6q 1604 5 6 6 CD cord-006870-f5w6fw6q 1604 6 were be VBD cord-006870-f5w6fw6q 1604 7 considered consider VBN cord-006870-f5w6fw6q 1604 8 poor poor JJ cord-006870-f5w6fw6q 1604 9 outcomes outcome NNS cord-006870-f5w6fw6q 1604 10 . . . cord-006870-f5w6fw6q 1605 1 Statistical statistical JJ cord-006870-f5w6fw6q 1605 2 analysis analysis NN cord-006870-f5w6fw6q 1605 3 was be VBD cord-006870-f5w6fw6q 1605 4 done do VBN cord-006870-f5w6fw6q 1605 5 after after IN cord-006870-f5w6fw6q 1605 6 grouping group VBG cord-006870-f5w6fw6q 1605 7 lab lab NN cord-006870-f5w6fw6q 1605 8 values value NNS cord-006870-f5w6fw6q 1605 9 into into IN cord-006870-f5w6fw6q 1605 10 higher high JJR cord-006870-f5w6fw6q 1605 11 and and CC cord-006870-f5w6fw6q 1605 12 lower low JJR cord-006870-f5w6fw6q 1605 13 groups group NNS cord-006870-f5w6fw6q 1605 14 with with IN cord-006870-f5w6fw6q 1605 15 respect respect NN cord-006870-f5w6fw6q 1605 16 to to IN cord-006870-f5w6fw6q 1605 17 the the DT cord-006870-f5w6fw6q 1605 18 normal normal JJ cord-006870-f5w6fw6q 1605 19 reference reference NN cord-006870-f5w6fw6q 1605 20 ranges range NNS cord-006870-f5w6fw6q 1606 1 A a DT cord-006870-f5w6fw6q 1606 2 total total NN cord-006870-f5w6fw6q 1606 3 of of IN cord-006870-f5w6fw6q 1606 4 257 257 CD cord-006870-f5w6fw6q 1606 5 patients patient NNS cord-006870-f5w6fw6q 1606 6 with with IN cord-006870-f5w6fw6q 1606 7 ICH ICH NNP cord-006870-f5w6fw6q 1606 8 were be VBD cord-006870-f5w6fw6q 1606 9 admitted admit VBN cord-006870-f5w6fw6q 1606 10 to to IN cord-006870-f5w6fw6q 1606 11 our -PRON- PRP$ cord-006870-f5w6fw6q 1606 12 center center NN cord-006870-f5w6fw6q 1606 13 during during IN cord-006870-f5w6fw6q 1606 14 the the DT cord-006870-f5w6fw6q 1606 15 study study NN cord-006870-f5w6fw6q 1606 16 period period NN cord-006870-f5w6fw6q 1606 17 . . . cord-006870-f5w6fw6q 1607 1 111 111 CD cord-006870-f5w6fw6q 1607 2 patients patient NNS cord-006870-f5w6fw6q 1607 3 were be VBD cord-006870-f5w6fw6q 1607 4 included include VBN cord-006870-f5w6fw6q 1607 5 in in IN cord-006870-f5w6fw6q 1607 6 the the DT cord-006870-f5w6fw6q 1607 7 study study NN cord-006870-f5w6fw6q 1607 8 and and CC cord-006870-f5w6fw6q 1607 9 the the DT cord-006870-f5w6fw6q 1607 10 rest rest NN cord-006870-f5w6fw6q 1607 11 were be VBD cord-006870-f5w6fw6q 1607 12 excluded exclude VBN cord-006870-f5w6fw6q 1607 13 due due IN cord-006870-f5w6fw6q 1607 14 to to IN cord-006870-f5w6fw6q 1607 15 lack lack NN cord-006870-f5w6fw6q 1607 16 of of IN cord-006870-f5w6fw6q 1607 17 differential differential JJ cord-006870-f5w6fw6q 1607 18 leucocyte leucocyte NN cord-006870-f5w6fw6q 1607 19 counts count VBZ cord-006870-f5w6fw6q 1607 20 at at IN cord-006870-f5w6fw6q 1607 21 admission admission NN cord-006870-f5w6fw6q 1607 22 . . . cord-006870-f5w6fw6q 1608 1 34 34 CD cord-006870-f5w6fw6q 1608 2 % % NN cord-006870-f5w6fw6q 1608 3 ( ( -LRB- cord-006870-f5w6fw6q 1608 4 38 38 CD cord-006870-f5w6fw6q 1608 5 of of IN cord-006870-f5w6fw6q 1608 6 111 111 CD cord-006870-f5w6fw6q 1608 7 ) ) -RRB- cord-006870-f5w6fw6q 1608 8 had have VBD cord-006870-f5w6fw6q 1608 9 poor poor JJ cord-006870-f5w6fw6q 1608 10 outcomes outcome NNS cord-006870-f5w6fw6q 1608 11 . . . cord-006870-f5w6fw6q 1609 1 Univariate Univariate NNP cord-006870-f5w6fw6q 1609 2 analysis analysis NN cord-006870-f5w6fw6q 1609 3 using use VBG cord-006870-f5w6fw6q 1609 4 Fisher Fisher NNP cord-006870-f5w6fw6q 1609 5 's 's POS cord-006870-f5w6fw6q 1609 6 exact exact JJ cord-006870-f5w6fw6q 1609 7 test test NN cord-006870-f5w6fw6q 1609 8 showed show VBD cord-006870-f5w6fw6q 1609 9 significant significant JJ cord-006870-f5w6fw6q 1609 10 association association NN cord-006870-f5w6fw6q 1609 11 between between IN cord-006870-f5w6fw6q 1609 12 low low JJ cord-006870-f5w6fw6q 1609 13 ALC ALC NNP cord-006870-f5w6fw6q 1609 14 levels level NNS cord-006870-f5w6fw6q 1609 15 ( ( -LRB- cord-006870-f5w6fw6q 1609 16 10.5 10.5 CD cord-006870-f5w6fw6q 1609 17 ) ) -RRB- cord-006870-f5w6fw6q 1609 18 were be VBD cord-006870-f5w6fw6q 1609 19 also also RB cord-006870-f5w6fw6q 1609 20 found find VBN cord-006870-f5w6fw6q 1609 21 to to TO cord-006870-f5w6fw6q 1609 22 be be VB cord-006870-f5w6fw6q 1609 23 significantly significantly RB cord-006870-f5w6fw6q 1609 24 associated associate VBN cord-006870-f5w6fw6q 1609 25 with with IN cord-006870-f5w6fw6q 1609 26 worse bad JJR cord-006870-f5w6fw6q 1609 27 outcomes outcome NNS cord-006870-f5w6fw6q 1609 28 ( ( -LRB- cord-006870-f5w6fw6q 1609 29 p p NN cord-006870-f5w6fw6q 1609 30 = = SYM cord-006870-f5w6fw6q 1609 31 0.0036 0.0036 CD cord-006870-f5w6fw6q 1609 32 , , , cord-006870-f5w6fw6q 1609 33 0.0001 0.0001 CD cord-006870-f5w6fw6q 1609 34 , , , cord-006870-f5w6fw6q 1609 35 0.0022 0.0022 CD cord-006870-f5w6fw6q 1609 36 , , , cord-006870-f5w6fw6q 1609 37 respectively respectively RB cord-006870-f5w6fw6q 1609 38 ) ) -RRB- cord-006870-f5w6fw6q 1609 39 . . . cord-006870-f5w6fw6q 1610 1 However however RB cord-006870-f5w6fw6q 1610 2 , , , cord-006870-f5w6fw6q 1610 3 after after IN cord-006870-f5w6fw6q 1610 4 multivariate multivariate JJ cord-006870-f5w6fw6q 1610 5 analysis analysis NN cord-006870-f5w6fw6q 1610 6 , , , cord-006870-f5w6fw6q 1610 7 only only RB cord-006870-f5w6fw6q 1610 8 low low JJ cord-006870-f5w6fw6q 1610 9 absolute absolute JJ cord-006870-f5w6fw6q 1610 10 lymphocyte lymphocyte NN cord-006870-f5w6fw6q 1610 11 counts count NNS cord-006870-f5w6fw6q 1610 12 retained retain VBD cord-006870-f5w6fw6q 1610 13 significant significant JJ cord-006870-f5w6fw6q 1610 14 association association NN cord-006870-f5w6fw6q 1610 15 ( ( -LRB- cord-006870-f5w6fw6q 1610 16 p p NN cord-006870-f5w6fw6q 1610 17 = = SYM cord-006870-f5w6fw6q 1610 18 0.0268 0.0268 CD cord-006870-f5w6fw6q 1610 19 ) ) -RRB- cord-006870-f5w6fw6q 1610 20 . . . cord-006870-f5w6fw6q 1611 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1611 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1611 3 patients patient NNS cord-006870-f5w6fw6q 1611 4 with with IN cord-006870-f5w6fw6q 1611 5 low low JJ cord-006870-f5w6fw6q 1611 6 absolute absolute JJ cord-006870-f5w6fw6q 1611 7 lymphocyte lymphocyte NN cord-006870-f5w6fw6q 1611 8 counts count VBZ cord-006870-f5w6fw6q 1611 9 at at IN cord-006870-f5w6fw6q 1611 10 admission admission NN cord-006870-f5w6fw6q 1611 11 have have VBP cord-006870-f5w6fw6q 1611 12 a a DT cord-006870-f5w6fw6q 1611 13 higher high JJR cord-006870-f5w6fw6q 1611 14 probability probability NN cord-006870-f5w6fw6q 1611 15 of of IN cord-006870-f5w6fw6q 1611 16 poor poor JJ cord-006870-f5w6fw6q 1611 17 outcomes outcome NNS cord-006870-f5w6fw6q 1611 18 at at IN cord-006870-f5w6fw6q 1611 19 discharge discharge NN cord-006870-f5w6fw6q 1611 20 . . . cord-006870-f5w6fw6q 1612 1 Further further JJ cord-006870-f5w6fw6q 1612 2 studies study NNS cord-006870-f5w6fw6q 1612 3 are be VBP cord-006870-f5w6fw6q 1612 4 required require VBN cord-006870-f5w6fw6q 1612 5 to to TO cord-006870-f5w6fw6q 1612 6 confirm confirm VB cord-006870-f5w6fw6q 1612 7 our -PRON- PRP$ cord-006870-f5w6fw6q 1612 8 results result NNS cord-006870-f5w6fw6q 1612 9 . . . cord-006870-f5w6fw6q 1613 1 Intraventricular intraventricular JJ cord-006870-f5w6fw6q 1613 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1613 3 ( ( -LRB- cord-006870-f5w6fw6q 1613 4 IVH IVH NNP cord-006870-f5w6fw6q 1613 5 ) ) -RRB- cord-006870-f5w6fw6q 1613 6 is be VBZ cord-006870-f5w6fw6q 1613 7 a a DT cord-006870-f5w6fw6q 1613 8 significant significant JJ cord-006870-f5w6fw6q 1613 9 predictor predictor NN cord-006870-f5w6fw6q 1613 10 of of IN cord-006870-f5w6fw6q 1613 11 poor poor JJ cord-006870-f5w6fw6q 1613 12 outcome outcome NN cord-006870-f5w6fw6q 1613 13 after after IN cord-006870-f5w6fw6q 1613 14 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1613 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1613 16 ( ( -LRB- cord-006870-f5w6fw6q 1613 17 ICH ICH NNP cord-006870-f5w6fw6q 1613 18 ) ) -RRB- cord-006870-f5w6fw6q 1613 19 , , , cord-006870-f5w6fw6q 1613 20 and and CC cord-006870-f5w6fw6q 1613 21 may may MD cord-006870-f5w6fw6q 1613 22 differentially differentially RB cord-006870-f5w6fw6q 1613 23 predict predict VB cord-006870-f5w6fw6q 1613 24 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 1613 25 and and CC cord-006870-f5w6fw6q 1613 26 mortality mortality NN cord-006870-f5w6fw6q 1613 27 among among IN cord-006870-f5w6fw6q 1613 28 blacks black NNS cord-006870-f5w6fw6q 1613 29 vs. vs. IN cord-006870-f5w6fw6q 1613 30 nonblacks nonblack NNS cord-006870-f5w6fw6q 1613 31 . . . cord-006870-f5w6fw6q 1614 1 We -PRON- PRP cord-006870-f5w6fw6q 1614 2 aimed aim VBD cord-006870-f5w6fw6q 1614 3 to to TO cord-006870-f5w6fw6q 1614 4 confirm confirm VB cord-006870-f5w6fw6q 1614 5 these these DT cord-006870-f5w6fw6q 1614 6 findings finding NNS cord-006870-f5w6fw6q 1614 7 in in IN cord-006870-f5w6fw6q 1614 8 a a DT cord-006870-f5w6fw6q 1614 9 separate separate JJ cord-006870-f5w6fw6q 1614 10 cohort cohort NN cord-006870-f5w6fw6q 1614 11 of of IN cord-006870-f5w6fw6q 1614 12 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1614 13 ICH ICH NNP cord-006870-f5w6fw6q 1614 14 patients patient NNS cord-006870-f5w6fw6q 1614 15 with with IN cord-006870-f5w6fw6q 1614 16 severe severe JJ cord-006870-f5w6fw6q 1614 17 IVH IVH NNP cord-006870-f5w6fw6q 1614 18 . . . cord-006870-f5w6fw6q 1615 1 The the DT cord-006870-f5w6fw6q 1615 2 CLEARIII CLEARIII NNP cord-006870-f5w6fw6q 1615 3 - - HYPH cord-006870-f5w6fw6q 1615 4 IVH IVH NNP cord-006870-f5w6fw6q 1615 5 trial trial NN cord-006870-f5w6fw6q 1615 6 was be VBD cord-006870-f5w6fw6q 1615 7 a a DT cord-006870-f5w6fw6q 1615 8 randomized randomized JJ cord-006870-f5w6fw6q 1615 9 , , , cord-006870-f5w6fw6q 1615 10 multi multi JJ cord-006870-f5w6fw6q 1615 11 - - JJ cord-006870-f5w6fw6q 1615 12 center center JJ cord-006870-f5w6fw6q 1615 13 placebo placebo NN cord-006870-f5w6fw6q 1615 14 controlled control VBN cord-006870-f5w6fw6q 1615 15 trial trial NN cord-006870-f5w6fw6q 1615 16 examining examine VBG cord-006870-f5w6fw6q 1615 17 the the DT cord-006870-f5w6fw6q 1615 18 effect effect NN cord-006870-f5w6fw6q 1615 19 of of IN cord-006870-f5w6fw6q 1615 20 intraventricular intraventricular JJ cord-006870-f5w6fw6q 1615 21 alteplase alteplase NNP cord-006870-f5w6fw6q 1615 22 versus versus IN cord-006870-f5w6fw6q 1615 23 saline saline NN cord-006870-f5w6fw6q 1615 24 , , , cord-006870-f5w6fw6q 1615 25 on on IN cord-006870-f5w6fw6q 1615 26 outcomes outcome NNS cord-006870-f5w6fw6q 1615 27 in in IN cord-006870-f5w6fw6q 1615 28 patients patient NNS cord-006870-f5w6fw6q 1615 29 with with IN cord-006870-f5w6fw6q 1615 30 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1615 31 IVH IVH NNP cord-006870-f5w6fw6q 1615 32 . . . cord-006870-f5w6fw6q 1616 1 We -PRON- PRP cord-006870-f5w6fw6q 1616 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 1616 3 analyzed analyze VBD cord-006870-f5w6fw6q 1616 4 data datum NNS cord-006870-f5w6fw6q 1616 5 on on IN cord-006870-f5w6fw6q 1616 6 all all DT cord-006870-f5w6fw6q 1616 7 500 500 CD cord-006870-f5w6fw6q 1616 8 patients patient NNS cord-006870-f5w6fw6q 1616 9 , , , cord-006870-f5w6fw6q 1616 10 including include VBG cord-006870-f5w6fw6q 1616 11 self self NN cord-006870-f5w6fw6q 1616 12 - - HYPH cord-006870-f5w6fw6q 1616 13 reported report VBN cord-006870-f5w6fw6q 1616 14 race race NN cord-006870-f5w6fw6q 1616 15 / / SYM cord-006870-f5w6fw6q 1616 16 ethnicity ethnicity NN cord-006870-f5w6fw6q 1616 17 , , , cord-006870-f5w6fw6q 1616 18 medical medical JJ cord-006870-f5w6fw6q 1616 19 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 1616 20 , , , cord-006870-f5w6fw6q 1616 21 presentation presentation NN cord-006870-f5w6fw6q 1616 22 characteristics characteristic NNS cord-006870-f5w6fw6q 1616 23 and and CC cord-006870-f5w6fw6q 1616 24 functional functional JJ cord-006870-f5w6fw6q 1616 25 outcomes outcome NNS cord-006870-f5w6fw6q 1616 26 . . . cord-006870-f5w6fw6q 1617 1 Represented represent VBN cord-006870-f5w6fw6q 1617 2 race race NN cord-006870-f5w6fw6q 1617 3 / / SYM cord-006870-f5w6fw6q 1617 4 ethnic ethnic JJ cord-006870-f5w6fw6q 1617 5 groups group NNS cord-006870-f5w6fw6q 1617 6 with with IN cord-006870-f5w6fw6q 1617 7 > > XX cord-006870-f5w6fw6q 1617 8 5 5 CD cord-006870-f5w6fw6q 1617 9 subjects subject NNS cord-006870-f5w6fw6q 1617 10 per per IN cord-006870-f5w6fw6q 1617 11 group group NN cord-006870-f5w6fw6q 1617 12 were be VBD cord-006870-f5w6fw6q 1617 13 252(50.4 252(50.4 CD cord-006870-f5w6fw6q 1617 14 % % NN cord-006870-f5w6fw6q 1617 15 ) ) -RRB- cord-006870-f5w6fw6q 1618 1 White white JJ cord-006870-f5w6fw6q 1618 2 / / SYM cord-006870-f5w6fw6q 1618 3 non non JJ cord-006870-f5w6fw6q 1618 4 - - JJ cord-006870-f5w6fw6q 1618 5 Hispanic hispanic JJ cord-006870-f5w6fw6q 1618 6 ( ( -LRB- cord-006870-f5w6fw6q 1618 7 WNH WNH NNP cord-006870-f5w6fw6q 1618 8 ) ) -RRB- cord-006870-f5w6fw6q 1618 9 , , , cord-006870-f5w6fw6q 1618 10 53(10.6 53(10.6 CD cord-006870-f5w6fw6q 1618 11 % % NN cord-006870-f5w6fw6q 1618 12 ) ) -RRB- cord-006870-f5w6fw6q 1619 1 White white JJ cord-006870-f5w6fw6q 1619 2 / / SYM cord-006870-f5w6fw6q 1619 3 Hispanic hispanic JJ cord-006870-f5w6fw6q 1619 4 ( ( -LRB- cord-006870-f5w6fw6q 1619 5 WH WH NNP cord-006870-f5w6fw6q 1619 6 ) ) -RRB- cord-006870-f5w6fw6q 1619 7 , , , cord-006870-f5w6fw6q 1619 8 168(33.6 168(33.6 CD cord-006870-f5w6fw6q 1619 9 % % NN cord-006870-f5w6fw6q 1619 10 ) ) -RRB- cord-006870-f5w6fw6q 1620 1 Black black JJ cord-006870-f5w6fw6q 1620 2 / / SYM cord-006870-f5w6fw6q 1620 3 African african JJ cord-006870-f5w6fw6q 1620 4 American american JJ cord-006870-f5w6fw6q 1620 5 / / SYM cord-006870-f5w6fw6q 1620 6 non non JJ cord-006870-f5w6fw6q 1620 7 - - JJ cord-006870-f5w6fw6q 1620 8 Hispanic hispanic JJ cord-006870-f5w6fw6q 1620 9 ( ( -LRB- cord-006870-f5w6fw6q 1620 10 BNH BNH NNP cord-006870-f5w6fw6q 1620 11 ) ) -RRB- cord-006870-f5w6fw6q 1620 12 , , , cord-006870-f5w6fw6q 1620 13 and and CC cord-006870-f5w6fw6q 1620 14 14(2.8 14(2.8 CD cord-006870-f5w6fw6q 1620 15 % % NN cord-006870-f5w6fw6q 1620 16 ) ) -RRB- cord-006870-f5w6fw6q 1621 1 Asian Asian NNP cord-006870-f5w6fw6q 1621 2 . . . cord-006870-f5w6fw6q 1622 1 BNH BNH NNP cord-006870-f5w6fw6q 1622 2 were be VBD cord-006870-f5w6fw6q 1622 3 significantly significantly RB cord-006870-f5w6fw6q 1622 4 younger young JJR cord-006870-f5w6fw6q 1622 5 than than IN cord-006870-f5w6fw6q 1622 6 rest rest NN cord-006870-f5w6fw6q 1622 7 of of IN cord-006870-f5w6fw6q 1622 8 the the DT cord-006870-f5w6fw6q 1622 9 cohort cohort NN cord-006870-f5w6fw6q 1622 10 with with IN cord-006870-f5w6fw6q 1622 11 median median JJ cord-006870-f5w6fw6q 1622 12 age age NN cord-006870-f5w6fw6q 1622 13 [ [ -LRB- cord-006870-f5w6fw6q 1622 14 interquartile interquartile JJ cord-006870-f5w6fw6q 1622 15 range range NN cord-006870-f5w6fw6q 1622 16 ] ] -RRB- cord-006870-f5w6fw6q 1622 17 55 55 CD cord-006870-f5w6fw6q 1622 18 [ [ -LRB- cord-006870-f5w6fw6q 1622 19 46,60 46,60 CD cord-006870-f5w6fw6q 1622 20 ] ] -RRB- cord-006870-f5w6fw6q 1622 21 years year NNS cord-006870-f5w6fw6q 1622 22 , , , cord-006870-f5w6fw6q 1622 23 had have VBD cord-006870-f5w6fw6q 1622 24 more more JJR cord-006870-f5w6fw6q 1622 25 hypertension(97 hypertension(97 NNP cord-006870-f5w6fw6q 1622 26 % % NN cord-006870-f5w6fw6q 1622 27 , , , cord-006870-f5w6fw6q 1622 28 p=0.056 p=0.056 NNP cord-006870-f5w6fw6q 1622 29 ) ) -RRB- cord-006870-f5w6fw6q 1622 30 , , , cord-006870-f5w6fw6q 1622 31 and and CC cord-006870-f5w6fw6q 1622 32 significantly significantly RB cord-006870-f5w6fw6q 1622 33 higher high JJR cord-006870-f5w6fw6q 1622 34 rates rate NNS cord-006870-f5w6fw6q 1622 35 of of IN cord-006870-f5w6fw6q 1622 36 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1622 37 medication medication NN cord-006870-f5w6fw6q 1622 38 non non NN cord-006870-f5w6fw6q 1622 39 - - JJ cord-006870-f5w6fw6q 1622 40 compliance compliance JJ cord-006870-f5w6fw6q 1622 41 ( ( -LRB- cord-006870-f5w6fw6q 1622 42 70.8 70.8 CD cord-006870-f5w6fw6q 1622 43 % % NN cord-006870-f5w6fw6q 1622 44 , , , cord-006870-f5w6fw6q 1622 45 p=0.048 p=0.048 NNP cord-006870-f5w6fw6q 1622 46 ) ) -RRB- cord-006870-f5w6fw6q 1622 47 . . . cord-006870-f5w6fw6q 1623 1 WNH WNH NNP cord-006870-f5w6fw6q 1623 2 had have VBD cord-006870-f5w6fw6q 1623 3 more more RBR cord-006870-f5w6fw6q 1623 4 frequent frequent JJ cord-006870-f5w6fw6q 1623 5 coronary coronary JJ cord-006870-f5w6fw6q 1623 6 artery artery NN cord-006870-f5w6fw6q 1623 7 disease disease NN cord-006870-f5w6fw6q 1623 8 ( ( -LRB- cord-006870-f5w6fw6q 1623 9 14.7 14.7 CD cord-006870-f5w6fw6q 1623 10 % % NN cord-006870-f5w6fw6q 1623 11 , , , cord-006870-f5w6fw6q 1623 12 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1623 13 ) ) -RRB- cord-006870-f5w6fw6q 1623 14 , , , cord-006870-f5w6fw6q 1623 15 use use NN cord-006870-f5w6fw6q 1623 16 of of IN cord-006870-f5w6fw6q 1623 17 vitamin vitamin NN cord-006870-f5w6fw6q 1623 18 K K NNP cord-006870-f5w6fw6q 1623 19 antagonists antagonist NNS cord-006870-f5w6fw6q 1623 20 ( ( -LRB- cord-006870-f5w6fw6q 1623 21 10.7 10.7 CD cord-006870-f5w6fw6q 1623 22 % % NN cord-006870-f5w6fw6q 1623 23 , , , cord-006870-f5w6fw6q 1623 24 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 1623 25 ) ) -RRB- cord-006870-f5w6fw6q 1623 26 and and CC cord-006870-f5w6fw6q 1623 27 elevated elevate VBD cord-006870-f5w6fw6q 1623 28 INR INR NNP cord-006870-f5w6fw6q 1623 29 on on IN cord-006870-f5w6fw6q 1623 30 presentation presentation NN cord-006870-f5w6fw6q 1623 31 ( ( -LRB- cord-006870-f5w6fw6q 1623 32 9.1 9.1 CD cord-006870-f5w6fw6q 1623 33 % % NN cord-006870-f5w6fw6q 1623 34 , , , cord-006870-f5w6fw6q 1623 35 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 1623 36 ) ) -RRB- cord-006870-f5w6fw6q 1623 37 . . . cord-006870-f5w6fw6q 1624 1 BNH BNH NNP cord-006870-f5w6fw6q 1624 2 had have VBD cord-006870-f5w6fw6q 1624 3 significantly significantly RB cord-006870-f5w6fw6q 1624 4 more more RBR cord-006870-f5w6fw6q 1624 5 frequent frequent JJ cord-006870-f5w6fw6q 1624 6 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 1624 7 on on IN cord-006870-f5w6fw6q 1624 8 presentation presentation NN cord-006870-f5w6fw6q 1624 9 ( ( -LRB- cord-006870-f5w6fw6q 1624 10 23.8 23.8 CD cord-006870-f5w6fw6q 1624 11 % % NN cord-006870-f5w6fw6q 1624 12 , , , cord-006870-f5w6fw6q 1624 13 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 1624 14 ) ) -RRB- cord-006870-f5w6fw6q 1624 15 , , , cord-006870-f5w6fw6q 1624 16 and and CC cord-006870-f5w6fw6q 1624 17 a a DT cord-006870-f5w6fw6q 1624 18 higher high JJR cord-006870-f5w6fw6q 1624 19 rate rate NN cord-006870-f5w6fw6q 1624 20 of of IN cord-006870-f5w6fw6q 1624 21 ventriculoperitoneal ventriculoperitoneal NN cord-006870-f5w6fw6q 1624 22 shunt shunt NN cord-006870-f5w6fw6q 1624 23 placement placement NN cord-006870-f5w6fw6q 1624 24 ( ( -LRB- cord-006870-f5w6fw6q 1624 25 25 25 CD cord-006870-f5w6fw6q 1624 26 % % NN cord-006870-f5w6fw6q 1624 27 , , , cord-006870-f5w6fw6q 1624 28 p=0.015 p=0.015 NNP cord-006870-f5w6fw6q 1624 29 ) ) -RRB- cord-006870-f5w6fw6q 1624 30 . . . cord-006870-f5w6fw6q 1625 1 Neither neither CC cord-006870-f5w6fw6q 1625 2 ICH ICH NNP cord-006870-f5w6fw6q 1625 3 nor nor CC cord-006870-f5w6fw6q 1625 4 IVH IVH NNP cord-006870-f5w6fw6q 1625 5 volume volume NN cord-006870-f5w6fw6q 1625 6 at at IN cord-006870-f5w6fw6q 1625 7 enrollment enrollment NN cord-006870-f5w6fw6q 1625 8 , , , cord-006870-f5w6fw6q 1625 9 nor nor CC cord-006870-f5w6fw6q 1625 10 IVH IVH NNP cord-006870-f5w6fw6q 1625 11 remaining remain VBG cord-006870-f5w6fw6q 1625 12 at at IN cord-006870-f5w6fw6q 1625 13 end end NN cord-006870-f5w6fw6q 1625 14 of of IN cord-006870-f5w6fw6q 1625 15 treatment treatment NN cord-006870-f5w6fw6q 1625 16 differed differ VBD cord-006870-f5w6fw6q 1625 17 significantly significantly RB cord-006870-f5w6fw6q 1625 18 between between IN cord-006870-f5w6fw6q 1625 19 race race NN cord-006870-f5w6fw6q 1625 20 / / SYM cord-006870-f5w6fw6q 1625 21 ethnic ethnic JJ cord-006870-f5w6fw6q 1625 22 groups group NNS cord-006870-f5w6fw6q 1625 23 . . . cord-006870-f5w6fw6q 1626 1 However however RB cord-006870-f5w6fw6q 1626 2 , , , cord-006870-f5w6fw6q 1626 3 BNH BNH NNP cord-006870-f5w6fw6q 1626 4 patients patient NNS cord-006870-f5w6fw6q 1626 5 were be VBD cord-006870-f5w6fw6q 1626 6 more more RBR cord-006870-f5w6fw6q 1626 7 likely likely JJ cord-006870-f5w6fw6q 1626 8 to to TO cord-006870-f5w6fw6q 1626 9 have have VB cord-006870-f5w6fw6q 1626 10 greater great JJR cord-006870-f5w6fw6q 1626 11 than than IN cord-006870-f5w6fw6q 1626 12 80 80 CD cord-006870-f5w6fw6q 1626 13 % % NN cord-006870-f5w6fw6q 1626 14 IVH IVH NNP cord-006870-f5w6fw6q 1626 15 reduction reduction NN cord-006870-f5w6fw6q 1626 16 , , , cord-006870-f5w6fw6q 1626 17 a a DT cord-006870-f5w6fw6q 1626 18 recognized recognize VBN cord-006870-f5w6fw6q 1626 19 endpoint endpoint NN cord-006870-f5w6fw6q 1626 20 for for IN cord-006870-f5w6fw6q 1626 21 better well JJR cord-006870-f5w6fw6q 1626 22 functional functional JJ cord-006870-f5w6fw6q 1626 23 outcomes outcome NNS cord-006870-f5w6fw6q 1626 24 in in IN cord-006870-f5w6fw6q 1626 25 CLEARIII CLEARIII NNP cord-006870-f5w6fw6q 1626 26 ( ( -LRB- cord-006870-f5w6fw6q 1626 27 26.8 26.8 CD cord-006870-f5w6fw6q 1626 28 % % NN cord-006870-f5w6fw6q 1626 29 vs. vs. IN cord-006870-f5w6fw6q 1626 30 25%-WH 25%-wh CD cord-006870-f5w6fw6q 1626 31 ; ; : cord-006870-f5w6fw6q 1626 32 17.1%-WNH 17.1%-WNH NNP cord-006870-f5w6fw6q 1626 33 ; ; : cord-006870-f5w6fw6q 1626 34 7.1%-Asian 7.1%-asian CD cord-006870-f5w6fw6q 1626 35 ; ; : cord-006870-f5w6fw6q 1626 36 p=0.019 p=0.019 NNP cord-006870-f5w6fw6q 1626 37 ) ) -RRB- cord-006870-f5w6fw6q 1626 38 , , , cord-006870-f5w6fw6q 1626 39 and and CC cord-006870-f5w6fw6q 1626 40 this this DT cord-006870-f5w6fw6q 1626 41 difference difference NN cord-006870-f5w6fw6q 1626 42 persisted persist VBD cord-006870-f5w6fw6q 1626 43 in in IN cord-006870-f5w6fw6q 1626 44 those those DT cord-006870-f5w6fw6q 1626 45 who who WP cord-006870-f5w6fw6q 1626 46 received receive VBD cord-006870-f5w6fw6q 1626 47 intraventricular intraventricular JJ cord-006870-f5w6fw6q 1626 48 alteplase alteplase NN cord-006870-f5w6fw6q 1626 49 ( ( -LRB- cord-006870-f5w6fw6q 1626 50 p=0.04 p=0.04 NNP cord-006870-f5w6fw6q 1626 51 ) ) -RRB- cord-006870-f5w6fw6q 1626 52 and and CC cord-006870-f5w6fw6q 1626 53 after after IN cord-006870-f5w6fw6q 1626 54 adjustment adjustment NN cord-006870-f5w6fw6q 1626 55 for for IN cord-006870-f5w6fw6q 1626 56 diagnostic diagnostic JJ cord-006870-f5w6fw6q 1626 57 IVH IVH NNP cord-006870-f5w6fw6q 1626 58 volume volume NN cord-006870-f5w6fw6q 1626 59 ( ( -LRB- cord-006870-f5w6fw6q 1626 60 p=0.03 p=0.03 NN cord-006870-f5w6fw6q 1626 61 ) ) -RRB- cord-006870-f5w6fw6q 1626 62 . . . cord-006870-f5w6fw6q 1627 1 Race race NN cord-006870-f5w6fw6q 1627 2 / / SYM cord-006870-f5w6fw6q 1627 3 ethnicity ethnicity NN cord-006870-f5w6fw6q 1627 4 was be VBD cord-006870-f5w6fw6q 1627 5 not not RB cord-006870-f5w6fw6q 1627 6 an an DT cord-006870-f5w6fw6q 1627 7 independent independent JJ cord-006870-f5w6fw6q 1627 8 predictor predictor NN cord-006870-f5w6fw6q 1627 9 of of IN cord-006870-f5w6fw6q 1627 10 mortality mortality NN cord-006870-f5w6fw6q 1627 11 or or CC cord-006870-f5w6fw6q 1627 12 poor poor JJ cord-006870-f5w6fw6q 1627 13 outcome outcome NN cord-006870-f5w6fw6q 1627 14 at at IN cord-006870-f5w6fw6q 1627 15 30 30 CD cord-006870-f5w6fw6q 1627 16 or or CC cord-006870-f5w6fw6q 1627 17 180 180 CD cord-006870-f5w6fw6q 1627 18 days day NNS cord-006870-f5w6fw6q 1627 19 on on IN cord-006870-f5w6fw6q 1627 20 multivariable multivariable JJ cord-006870-f5w6fw6q 1627 21 logistic logistic JJ cord-006870-f5w6fw6q 1627 22 regression regression NN cord-006870-f5w6fw6q 1627 23 . . . cord-006870-f5w6fw6q 1628 1 Although although IN cord-006870-f5w6fw6q 1628 2 functional functional JJ cord-006870-f5w6fw6q 1628 3 outcomes outcome NNS cord-006870-f5w6fw6q 1628 4 did do VBD cord-006870-f5w6fw6q 1628 5 not not RB cord-006870-f5w6fw6q 1628 6 differ differ VB cord-006870-f5w6fw6q 1628 7 significantly significantly RB cord-006870-f5w6fw6q 1628 8 among among IN cord-006870-f5w6fw6q 1628 9 race race NN cord-006870-f5w6fw6q 1628 10 / / SYM cord-006870-f5w6fw6q 1628 11 ethnic ethnic JJ cord-006870-f5w6fw6q 1628 12 groups group NNS cord-006870-f5w6fw6q 1628 13 , , , cord-006870-f5w6fw6q 1628 14 differences difference NNS cord-006870-f5w6fw6q 1628 15 in in IN cord-006870-f5w6fw6q 1628 16 risk risk NN cord-006870-f5w6fw6q 1628 17 factors factor NNS cord-006870-f5w6fw6q 1628 18 , , , cord-006870-f5w6fw6q 1628 19 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 1628 20 / / SYM cord-006870-f5w6fw6q 1628 21 shunting shunt VBG cord-006870-f5w6fw6q 1628 22 post post NN cord-006870-f5w6fw6q 1628 23 IVH ivh NN cord-006870-f5w6fw6q 1628 24 and and CC cord-006870-f5w6fw6q 1628 25 response response NN cord-006870-f5w6fw6q 1628 26 to to IN cord-006870-f5w6fw6q 1628 27 thrombolytic thrombolytic NN cord-006870-f5w6fw6q 1628 28 therapy therapy NN cord-006870-f5w6fw6q 1628 29 warrant warrant VBP cord-006870-f5w6fw6q 1628 30 further further JJ cord-006870-f5w6fw6q 1628 31 exploration exploration NN cord-006870-f5w6fw6q 1628 32 . . . cord-006870-f5w6fw6q 1629 1 Investigators investigator NNS cord-006870-f5w6fw6q 1629 2 from from IN cord-006870-f5w6fw6q 1629 3 the the DT cord-006870-f5w6fw6q 1629 4 Randomized randomized JJ cord-006870-f5w6fw6q 1629 5 trial trial NN cord-006870-f5w6fw6q 1629 6 of of IN cord-006870-f5w6fw6q 1629 7 Unruptured Unruptured NNP cord-006870-f5w6fw6q 1629 8 Brain Brain NNP cord-006870-f5w6fw6q 1629 9 Arteriovenous Arteriovenous NNP cord-006870-f5w6fw6q 1629 10 malformations malformation NNS cord-006870-f5w6fw6q 1629 11 ( ( -LRB- cord-006870-f5w6fw6q 1629 12 AVM AVM NNP cord-006870-f5w6fw6q 1629 13 ) ) -RRB- cord-006870-f5w6fw6q 1629 14 trial trial NN cord-006870-f5w6fw6q 1629 15 ( ( -LRB- cord-006870-f5w6fw6q 1629 16 ARUBA ARUBA NNP cord-006870-f5w6fw6q 1629 17 ) ) -RRB- cord-006870-f5w6fw6q 1629 18 reported report VBD cord-006870-f5w6fw6q 1629 19 in in IN cord-006870-f5w6fw6q 1629 20 2013 2013 CD cord-006870-f5w6fw6q 1629 21 that that IN cord-006870-f5w6fw6q 1629 22 interventions intervention NNS cord-006870-f5w6fw6q 1629 23 to to TO cord-006870-f5w6fw6q 1629 24 obliterate obliterate VB cord-006870-f5w6fw6q 1629 25 unruptured unruptured JJ cord-006870-f5w6fw6q 1629 26 AVMs avm NNS cord-006870-f5w6fw6q 1629 27 resulted result VBD cord-006870-f5w6fw6q 1629 28 in in IN cord-006870-f5w6fw6q 1629 29 greater great JJR cord-006870-f5w6fw6q 1629 30 morbidity morbidity NN cord-006870-f5w6fw6q 1629 31 and and CC cord-006870-f5w6fw6q 1629 32 mortality mortality NN cord-006870-f5w6fw6q 1629 33 compared compare VBN cord-006870-f5w6fw6q 1629 34 to to IN cord-006870-f5w6fw6q 1629 35 medical medical JJ cord-006870-f5w6fw6q 1629 36 management management NN cord-006870-f5w6fw6q 1629 37 . . . cord-006870-f5w6fw6q 1630 1 We -PRON- PRP cord-006870-f5w6fw6q 1630 2 investigated investigate VBD cord-006870-f5w6fw6q 1630 3 whether whether IN cord-006870-f5w6fw6q 1630 4 patterns pattern NNS cord-006870-f5w6fw6q 1630 5 of of IN cord-006870-f5w6fw6q 1630 6 AVM AVM NNP cord-006870-f5w6fw6q 1630 7 treatment treatment NN cord-006870-f5w6fw6q 1630 8 changed change VBD cord-006870-f5w6fw6q 1630 9 after after IN cord-006870-f5w6fw6q 1630 10 ARUBA ARUBA NNP cord-006870-f5w6fw6q 1630 11 's 's POS cord-006870-f5w6fw6q 1630 12 publication publication NN cord-006870-f5w6fw6q 1630 13 . . . cord-006870-f5w6fw6q 1631 1 We -PRON- PRP cord-006870-f5w6fw6q 1631 2 used use VBD cord-006870-f5w6fw6q 1631 3 inpatient inpatient JJ cord-006870-f5w6fw6q 1631 4 and and CC cord-006870-f5w6fw6q 1631 5 outpatient outpatient NN cord-006870-f5w6fw6q 1631 6 claims claim NNS cord-006870-f5w6fw6q 1631 7 data datum NNS cord-006870-f5w6fw6q 1631 8 from from IN cord-006870-f5w6fw6q 1631 9 2009 2009 CD cord-006870-f5w6fw6q 1631 10 - - SYM cord-006870-f5w6fw6q 1631 11 2015 2015 CD cord-006870-f5w6fw6q 1631 12 from from IN cord-006870-f5w6fw6q 1631 13 a a DT cord-006870-f5w6fw6q 1631 14 nationally nationally RB cord-006870-f5w6fw6q 1631 15 representative representative JJ cord-006870-f5w6fw6q 1631 16 5 5 CD cord-006870-f5w6fw6q 1631 17 % % NN cord-006870-f5w6fw6q 1631 18 sample sample NN cord-006870-f5w6fw6q 1631 19 of of IN cord-006870-f5w6fw6q 1631 20 Medicare Medicare NNP cord-006870-f5w6fw6q 1631 21 beneficiaries beneficiary NNS cord-006870-f5w6fw6q 1631 22 . . . cord-006870-f5w6fw6q 1632 1 Unruptured unruptured JJ cord-006870-f5w6fw6q 1632 2 brain brain NN cord-006870-f5w6fw6q 1632 3 AVMs avm NNS cord-006870-f5w6fw6q 1632 4 were be VBD cord-006870-f5w6fw6q 1632 5 identified identify VBN cord-006870-f5w6fw6q 1632 6 using use VBG cord-006870-f5w6fw6q 1632 7 ICD-9-CM ICD-9-CM NNP cord-006870-f5w6fw6q 1632 8 code code NN cord-006870-f5w6fw6q 1632 9 747.81 747.81 CD cord-006870-f5w6fw6q 1632 10 . . . cord-006870-f5w6fw6q 1633 1 The the DT cord-006870-f5w6fw6q 1633 2 date date NN cord-006870-f5w6fw6q 1633 3 of of IN cord-006870-f5w6fw6q 1633 4 first first JJ cord-006870-f5w6fw6q 1633 5 AVM AVM NNP cord-006870-f5w6fw6q 1633 6 diagnosis diagnosis NN cord-006870-f5w6fw6q 1633 7 was be VBD cord-006870-f5w6fw6q 1633 8 coded code VBN cord-006870-f5w6fw6q 1633 9 as as IN cord-006870-f5w6fw6q 1633 10 occurring occur VBG cord-006870-f5w6fw6q 1633 11 before before IN cord-006870-f5w6fw6q 1633 12 or or CC cord-006870-f5w6fw6q 1633 13 on on IN cord-006870-f5w6fw6q 1633 14 November November NNP cord-006870-f5w6fw6q 1633 15 20 20 CD cord-006870-f5w6fw6q 1633 16 , , , cord-006870-f5w6fw6q 1633 17 2013 2013 CD cord-006870-f5w6fw6q 1633 18 ( ( -LRB- cord-006870-f5w6fw6q 1633 19 online online JJ cord-006870-f5w6fw6q 1633 20 publication publication NN cord-006870-f5w6fw6q 1633 21 of of IN cord-006870-f5w6fw6q 1633 22 ARUBA ARUBA NNP cord-006870-f5w6fw6q 1633 23 ) ) -RRB- cord-006870-f5w6fw6q 1633 24 versus versus IN cord-006870-f5w6fw6q 1633 25 after after RB cord-006870-f5w6fw6q 1633 26 . . . cord-006870-f5w6fw6q 1634 1 Outcomes outcome NNS cord-006870-f5w6fw6q 1634 2 were be VBD cord-006870-f5w6fw6q 1634 3 referral referral JJ cord-006870-f5w6fw6q 1634 4 to to IN cord-006870-f5w6fw6q 1634 5 a a DT cord-006870-f5w6fw6q 1634 6 neurologist neurologist NN cord-006870-f5w6fw6q 1634 7 or or CC cord-006870-f5w6fw6q 1634 8 neurosurgeon neurosurgeon NN cord-006870-f5w6fw6q 1634 9 , , , cord-006870-f5w6fw6q 1634 10 and and CC cord-006870-f5w6fw6q 1634 11 interventional interventional JJ cord-006870-f5w6fw6q 1634 12 treatment treatment NN cord-006870-f5w6fw6q 1634 13 . . . cord-006870-f5w6fw6q 1635 1 Interventional interventional JJ cord-006870-f5w6fw6q 1635 2 treatments treatment NNS cord-006870-f5w6fw6q 1635 3 were be VBD cord-006870-f5w6fw6q 1635 4 identified identify VBN cord-006870-f5w6fw6q 1635 5 using use VBG cord-006870-f5w6fw6q 1635 6 CPT CPT NNP cord-006870-f5w6fw6q 1635 7 codes code NNS cord-006870-f5w6fw6q 1635 8 61680 61680 CD cord-006870-f5w6fw6q 1635 9 - - SYM cord-006870-f5w6fw6q 1635 10 61692 61692 CD cord-006870-f5w6fw6q 1635 11 , , , cord-006870-f5w6fw6q 1635 12 61623 61623 CD cord-006870-f5w6fw6q 1635 13 - - SYM cord-006870-f5w6fw6q 1635 14 61624 61624 CD cord-006870-f5w6fw6q 1635 15 , , , cord-006870-f5w6fw6q 1635 16 61796 61796 CD cord-006870-f5w6fw6q 1635 17 , , , cord-006870-f5w6fw6q 1635 18 61798 61798 CD cord-006870-f5w6fw6q 1635 19 , , , cord-006870-f5w6fw6q 1635 20 or or CC cord-006870-f5w6fw6q 1635 21 77371 77371 CD cord-006870-f5w6fw6q 1635 22 - - HYPH cord-006870-f5w6fw6q 1635 23 77372 77372 CD cord-006870-f5w6fw6q 1635 24 . . . cord-006870-f5w6fw6q 1636 1 The the DT cord-006870-f5w6fw6q 1636 2 likelihood likelihood NN cord-006870-f5w6fw6q 1636 3 of of IN cord-006870-f5w6fw6q 1636 4 outcomes outcome NNS cord-006870-f5w6fw6q 1636 5 after after IN cord-006870-f5w6fw6q 1636 6 versus versus IN cord-006870-f5w6fw6q 1636 7 before before IN cord-006870-f5w6fw6q 1636 8 ARUBA ARUBA NNP cord-006870-f5w6fw6q 1636 9 was be VBD cord-006870-f5w6fw6q 1636 10 compared compare VBN cord-006870-f5w6fw6q 1636 11 using use VBG cord-006870-f5w6fw6q 1636 12 survival survival NN cord-006870-f5w6fw6q 1636 13 analysis analysis NN cord-006870-f5w6fw6q 1636 14 with with IN cord-006870-f5w6fw6q 1636 15 log log NN cord-006870-f5w6fw6q 1636 16 - - HYPH cord-006870-f5w6fw6q 1636 17 rank rank NN cord-006870-f5w6fw6q 1636 18 tests test NNS cord-006870-f5w6fw6q 1636 19 and and CC cord-006870-f5w6fw6q 1636 20 Cox Cox NNP cord-006870-f5w6fw6q 1636 21 proportional proportional JJ cord-006870-f5w6fw6q 1636 22 hazards hazard NNS cord-006870-f5w6fw6q 1636 23 models model NNS cord-006870-f5w6fw6q 1636 24 adjusted adjust VBN cord-006870-f5w6fw6q 1636 25 for for IN cord-006870-f5w6fw6q 1636 26 age age NN cord-006870-f5w6fw6q 1636 27 , , , cord-006870-f5w6fw6q 1636 28 sex sex NN cord-006870-f5w6fw6q 1636 29 , , , cord-006870-f5w6fw6q 1636 30 race race NN cord-006870-f5w6fw6q 1636 31 , , , cord-006870-f5w6fw6q 1636 32 and and CC cord-006870-f5w6fw6q 1636 33 the the DT cord-006870-f5w6fw6q 1636 34 Charlson Charlson NNP cord-006870-f5w6fw6q 1636 35 Comorbidity Comorbidity NNP cord-006870-f5w6fw6q 1636 36 Index Index NNP cord-006870-f5w6fw6q 1636 37 . . . cord-006870-f5w6fw6q 1637 1 We -PRON- PRP cord-006870-f5w6fw6q 1637 2 censored censor VBD cord-006870-f5w6fw6q 1637 3 patients patient NNS cord-006870-f5w6fw6q 1637 4 at at IN cord-006870-f5w6fw6q 1637 5 diagnosis diagnosis NN cord-006870-f5w6fw6q 1637 6 of of IN cord-006870-f5w6fw6q 1637 7 intracranial intracranial JJ cord-006870-f5w6fw6q 1637 8 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1637 9 . . . cord-006870-f5w6fw6q 1638 1 We -PRON- PRP cord-006870-f5w6fw6q 1638 2 identified identify VBD cord-006870-f5w6fw6q 1638 3 1,444 1,444 CD cord-006870-f5w6fw6q 1638 4 patients patient NNS cord-006870-f5w6fw6q 1638 5 with with IN cord-006870-f5w6fw6q 1638 6 a a DT cord-006870-f5w6fw6q 1638 7 mean mean JJ cord-006870-f5w6fw6q 1638 8 2.8 2.8 CD cord-006870-f5w6fw6q 1638 9 ( ( -LRB- cord-006870-f5w6fw6q 1638 10 ±2.0 ±2.0 NNS cord-006870-f5w6fw6q 1638 11 ) ) -RRB- cord-006870-f5w6fw6q 1638 12 years year NNS cord-006870-f5w6fw6q 1638 13 of of IN cord-006870-f5w6fw6q 1638 14 follow follow NN cord-006870-f5w6fw6q 1638 15 - - HYPH cord-006870-f5w6fw6q 1638 16 up up NN cord-006870-f5w6fw6q 1638 17 after after IN cord-006870-f5w6fw6q 1638 18 diagnosis diagnosis NN cord-006870-f5w6fw6q 1638 19 of of IN cord-006870-f5w6fw6q 1638 20 unruptured unruptured JJ cord-006870-f5w6fw6q 1638 21 brain brain NN cord-006870-f5w6fw6q 1638 22 AVM AVM NNP cord-006870-f5w6fw6q 1638 23 . . . cord-006870-f5w6fw6q 1639 1 Diagnosis diagnosis NN cord-006870-f5w6fw6q 1639 2 was be VBD cord-006870-f5w6fw6q 1639 3 most most RBS cord-006870-f5w6fw6q 1639 4 often often RB cord-006870-f5w6fw6q 1639 5 by by IN cord-006870-f5w6fw6q 1639 6 neurologists neurologist NNS cord-006870-f5w6fw6q 1639 7 ( ( -LRB- cord-006870-f5w6fw6q 1639 8 20.6 20.6 CD cord-006870-f5w6fw6q 1639 9 % % NN cord-006870-f5w6fw6q 1639 10 ) ) -RRB- cord-006870-f5w6fw6q 1639 11 , , , cord-006870-f5w6fw6q 1639 12 neurosurgeons neurosurgeon NNS cord-006870-f5w6fw6q 1639 13 ( ( -LRB- cord-006870-f5w6fw6q 1639 14 14.4 14.4 CD cord-006870-f5w6fw6q 1639 15 % % NN cord-006870-f5w6fw6q 1639 16 ) ) -RRB- cord-006870-f5w6fw6q 1639 17 , , , cord-006870-f5w6fw6q 1639 18 and and CC cord-006870-f5w6fw6q 1639 19 internal internal JJ cord-006870-f5w6fw6q 1639 20 medicine medicine NN cord-006870-f5w6fw6q 1639 21 specialists specialist NNS cord-006870-f5w6fw6q 1639 22 ( ( -LRB- cord-006870-f5w6fw6q 1639 23 11.3 11.3 CD cord-006870-f5w6fw6q 1639 24 % % NN cord-006870-f5w6fw6q 1639 25 ) ) -RRB- cord-006870-f5w6fw6q 1639 26 . . . cord-006870-f5w6fw6q 1640 1 After after IN cord-006870-f5w6fw6q 1640 2 ARUBA ARUBA NNP cord-006870-f5w6fw6q 1640 3 publication publication NN cord-006870-f5w6fw6q 1640 4 , , , cord-006870-f5w6fw6q 1640 5 there there EX cord-006870-f5w6fw6q 1640 6 were be VBD cord-006870-f5w6fw6q 1640 7 no no DT cord-006870-f5w6fw6q 1640 8 changes change NNS cord-006870-f5w6fw6q 1640 9 in in IN cord-006870-f5w6fw6q 1640 10 1-year 1-year CD cord-006870-f5w6fw6q 1640 11 cumulative cumulative JJ cord-006870-f5w6fw6q 1640 12 rates rate NNS cord-006870-f5w6fw6q 1640 13 of of IN cord-006870-f5w6fw6q 1640 14 referral referral NN cord-006870-f5w6fw6q 1640 15 to to IN cord-006870-f5w6fw6q 1640 16 a a DT cord-006870-f5w6fw6q 1640 17 neurosurgeon neurosurgeon NN cord-006870-f5w6fw6q 1640 18 ( ( -LRB- cord-006870-f5w6fw6q 1640 19 26.9 26.9 CD cord-006870-f5w6fw6q 1640 20 % % NN cord-006870-f5w6fw6q 1640 21 after after IN cord-006870-f5w6fw6q 1640 22 , , , cord-006870-f5w6fw6q 1640 23 26.8 26.8 CD cord-006870-f5w6fw6q 1640 24 % % NN cord-006870-f5w6fw6q 1640 25 before before RB cord-006870-f5w6fw6q 1640 26 ; ; : cord-006870-f5w6fw6q 1640 27 P p NN cord-006870-f5w6fw6q 1640 28 = = SYM cord-006870-f5w6fw6q 1640 29 0.99 0.99 CD cord-006870-f5w6fw6q 1640 30 ) ) -RRB- cord-006870-f5w6fw6q 1640 31 or or CC cord-006870-f5w6fw6q 1640 32 neurologist neurologist NN cord-006870-f5w6fw6q 1640 33 ( ( -LRB- cord-006870-f5w6fw6q 1640 34 46.8 46.8 CD cord-006870-f5w6fw6q 1640 35 % % NN cord-006870-f5w6fw6q 1640 36 after after IN cord-006870-f5w6fw6q 1640 37 , , , cord-006870-f5w6fw6q 1640 38 47.7 47.7 CD cord-006870-f5w6fw6q 1640 39 % % NN cord-006870-f5w6fw6q 1640 40 before before RB cord-006870-f5w6fw6q 1640 41 ; ; : cord-006870-f5w6fw6q 1640 42 P p NN cord-006870-f5w6fw6q 1640 43 = = SYM cord-006870-f5w6fw6q 1640 44 0.97 0.97 CD cord-006870-f5w6fw6q 1640 45 ) ) -RRB- cord-006870-f5w6fw6q 1640 46 , , , cord-006870-f5w6fw6q 1640 47 but but CC cord-006870-f5w6fw6q 1640 48 there there EX cord-006870-f5w6fw6q 1640 49 was be VBD cord-006870-f5w6fw6q 1640 50 an an DT cord-006870-f5w6fw6q 1640 51 increase increase NN cord-006870-f5w6fw6q 1640 52 in in IN cord-006870-f5w6fw6q 1640 53 AVM AVM NNP cord-006870-f5w6fw6q 1640 54 treatment treatment NN cord-006870-f5w6fw6q 1640 55 ( ( -LRB- cord-006870-f5w6fw6q 1640 56 7.0 7.0 CD cord-006870-f5w6fw6q 1640 57 % % NN cord-006870-f5w6fw6q 1640 58 after after IN cord-006870-f5w6fw6q 1640 59 , , , cord-006870-f5w6fw6q 1640 60 3.5 3.5 CD cord-006870-f5w6fw6q 1640 61 % % NN cord-006870-f5w6fw6q 1640 62 before before RB cord-006870-f5w6fw6q 1640 63 ; ; : cord-006870-f5w6fw6q 1640 64 P p NN cord-006870-f5w6fw6q 1640 65 = = SYM cord-006870-f5w6fw6q 1640 66 0.0096 0.0096 CD cord-006870-f5w6fw6q 1640 67 ) ) -RRB- cord-006870-f5w6fw6q 1640 68 . . . cord-006870-f5w6fw6q 1641 1 After after IN cord-006870-f5w6fw6q 1641 2 adjustment adjustment NN cord-006870-f5w6fw6q 1641 3 for for IN cord-006870-f5w6fw6q 1641 4 demographics demographic NNS cord-006870-f5w6fw6q 1641 5 and and CC cord-006870-f5w6fw6q 1641 6 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 1641 7 , , , cord-006870-f5w6fw6q 1641 8 there there EX cord-006870-f5w6fw6q 1641 9 was be VBD cord-006870-f5w6fw6q 1641 10 an an DT cord-006870-f5w6fw6q 1641 11 increased increase VBN cord-006870-f5w6fw6q 1641 12 likelihood likelihood NN cord-006870-f5w6fw6q 1641 13 of of IN cord-006870-f5w6fw6q 1641 14 interventional interventional JJ cord-006870-f5w6fw6q 1641 15 management management NN cord-006870-f5w6fw6q 1641 16 ( ( -LRB- cord-006870-f5w6fw6q 1641 17 HR HR NNP cord-006870-f5w6fw6q 1641 18 1.9 1.9 CD cord-006870-f5w6fw6q 1641 19 ; ; : cord-006870-f5w6fw6q 1641 20 95 95 CD cord-006870-f5w6fw6q 1641 21 % % NN cord-006870-f5w6fw6q 1641 22 CI CI NNP cord-006870-f5w6fw6q 1641 23 , , , cord-006870-f5w6fw6q 1641 24 1.1 1.1 CD cord-006870-f5w6fw6q 1641 25 - - SYM cord-006870-f5w6fw6q 1641 26 3.2 3.2 CD cord-006870-f5w6fw6q 1641 27 ) ) -RRB- cord-006870-f5w6fw6q 1641 28 after after IN cord-006870-f5w6fw6q 1641 29 ARUBA ARUBA NNP cord-006870-f5w6fw6q 1641 30 's 's POS cord-006870-f5w6fw6q 1641 31 publication publication NN cord-006870-f5w6fw6q 1641 32 . . . cord-006870-f5w6fw6q 1642 1 In in IN cord-006870-f5w6fw6q 1642 2 a a DT cord-006870-f5w6fw6q 1642 3 nationally nationally RB cord-006870-f5w6fw6q 1642 4 representative representative JJ cord-006870-f5w6fw6q 1642 5 cohort cohort NN cord-006870-f5w6fw6q 1642 6 of of IN cord-006870-f5w6fw6q 1642 7 elderly elderly JJ cord-006870-f5w6fw6q 1642 8 patients patient NNS cord-006870-f5w6fw6q 1642 9 , , , cord-006870-f5w6fw6q 1642 10 we -PRON- PRP cord-006870-f5w6fw6q 1642 11 found find VBD cord-006870-f5w6fw6q 1642 12 an an DT cord-006870-f5w6fw6q 1642 13 increase increase NN cord-006870-f5w6fw6q 1642 14 in in IN cord-006870-f5w6fw6q 1642 15 interventional interventional JJ cord-006870-f5w6fw6q 1642 16 AVM AVM NNP cord-006870-f5w6fw6q 1642 17 management management NN cord-006870-f5w6fw6q 1642 18 after after IN cord-006870-f5w6fw6q 1642 19 publication publication NN cord-006870-f5w6fw6q 1642 20 of of IN cord-006870-f5w6fw6q 1642 21 ARUBA ARUBA NNP cord-006870-f5w6fw6q 1642 22 . . . cord-006870-f5w6fw6q 1643 1 This this DT cord-006870-f5w6fw6q 1643 2 is be VBZ cord-006870-f5w6fw6q 1643 3 notable notable JJ cord-006870-f5w6fw6q 1643 4 given give VBN cord-006870-f5w6fw6q 1643 5 that that IN cord-006870-f5w6fw6q 1643 6 our -PRON- PRP$ cord-006870-f5w6fw6q 1643 7 data datum NNS cord-006870-f5w6fw6q 1643 8 pertain pertain VBP cord-006870-f5w6fw6q 1643 9 to to IN cord-006870-f5w6fw6q 1643 10 older old JJR cord-006870-f5w6fw6q 1643 11 patients patient NNS cord-006870-f5w6fw6q 1643 12 who who WP cord-006870-f5w6fw6q 1643 13 are be VBP cord-006870-f5w6fw6q 1643 14 generally generally RB cord-006870-f5w6fw6q 1643 15 seen see VBN cord-006870-f5w6fw6q 1643 16 as as IN cord-006870-f5w6fw6q 1643 17 less less RBR cord-006870-f5w6fw6q 1643 18 suitable suitable JJ cord-006870-f5w6fw6q 1643 19 surgical surgical JJ cord-006870-f5w6fw6q 1643 20 candidates candidate NNS cord-006870-f5w6fw6q 1643 21 . . . cord-006870-f5w6fw6q 1644 1 Elderly elderly JJ cord-006870-f5w6fw6q 1644 2 patients patient NNS cord-006870-f5w6fw6q 1644 3 with with IN cord-006870-f5w6fw6q 1644 4 severe severe JJ cord-006870-f5w6fw6q 1644 5 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1644 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1644 7 ( ( -LRB- cord-006870-f5w6fw6q 1644 8 ICH ICH NNP cord-006870-f5w6fw6q 1644 9 ) ) -RRB- cord-006870-f5w6fw6q 1644 10 are be VBP cord-006870-f5w6fw6q 1644 11 often often RB cord-006870-f5w6fw6q 1644 12 projected project VBN cord-006870-f5w6fw6q 1644 13 to to TO cord-006870-f5w6fw6q 1644 14 have have VB cord-006870-f5w6fw6q 1644 15 future future JJ cord-006870-f5w6fw6q 1644 16 functional functional JJ cord-006870-f5w6fw6q 1644 17 dependence dependence NN cord-006870-f5w6fw6q 1644 18 but but CC cord-006870-f5w6fw6q 1644 19 unclear unclear JJ cord-006870-f5w6fw6q 1644 20 degree degree NN cord-006870-f5w6fw6q 1644 21 of of IN cord-006870-f5w6fw6q 1644 22 cognitive cognitive JJ cord-006870-f5w6fw6q 1644 23 recovery recovery NN cord-006870-f5w6fw6q 1644 24 . . . cord-006870-f5w6fw6q 1645 1 Surrogates surrogate NNS cord-006870-f5w6fw6q 1645 2 for for IN cord-006870-f5w6fw6q 1645 3 such such JJ cord-006870-f5w6fw6q 1645 4 patients patient NNS cord-006870-f5w6fw6q 1645 5 frequently frequently RB cord-006870-f5w6fw6q 1645 6 weigh weigh VBP cord-006870-f5w6fw6q 1645 7 multiple multiple JJ cord-006870-f5w6fw6q 1645 8 concerns concern NNS cord-006870-f5w6fw6q 1645 9 when when WRB cord-006870-f5w6fw6q 1645 10 facing face VBG cord-006870-f5w6fw6q 1645 11 the the DT cord-006870-f5w6fw6q 1645 12 difficult difficult JJ cord-006870-f5w6fw6q 1645 13 decision decision NN cord-006870-f5w6fw6q 1645 14 of of IN cord-006870-f5w6fw6q 1645 15 whether whether IN cord-006870-f5w6fw6q 1645 16 to to TO cord-006870-f5w6fw6q 1645 17 prolong prolong VB cord-006870-f5w6fw6q 1645 18 life life NN cord-006870-f5w6fw6q 1645 19 with with IN cord-006870-f5w6fw6q 1645 20 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 1645 21 and and CC cord-006870-f5w6fw6q 1645 22 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 1645 23 tube tube NN cord-006870-f5w6fw6q 1645 24 insertion insertion NN cord-006870-f5w6fw6q 1645 25 versus versus IN cord-006870-f5w6fw6q 1645 26 pursue pursue JJ cord-006870-f5w6fw6q 1645 27 comfort comfort NN cord-006870-f5w6fw6q 1645 28 care care NN cord-006870-f5w6fw6q 1645 29 . . . cord-006870-f5w6fw6q 1646 1 We -PRON- PRP cord-006870-f5w6fw6q 1646 2 aimed aim VBD cord-006870-f5w6fw6q 1646 3 to to TO cord-006870-f5w6fw6q 1646 4 characterize characterize VB cord-006870-f5w6fw6q 1646 5 distinct distinct JJ cord-006870-f5w6fw6q 1646 6 groups group NNS cord-006870-f5w6fw6q 1646 7 of of IN cord-006870-f5w6fw6q 1646 8 surrogates surrogate NNS cord-006870-f5w6fw6q 1646 9 in in IN cord-006870-f5w6fw6q 1646 10 these these DT cord-006870-f5w6fw6q 1646 11 situations situation NNS cord-006870-f5w6fw6q 1646 12 , , , cord-006870-f5w6fw6q 1646 13 based base VBN cord-006870-f5w6fw6q 1646 14 solely solely RB cord-006870-f5w6fw6q 1646 15 on on IN cord-006870-f5w6fw6q 1646 16 how how WRB cord-006870-f5w6fw6q 1646 17 they -PRON- PRP cord-006870-f5w6fw6q 1646 18 prioritize prioritize VBP cord-006870-f5w6fw6q 1646 19 their -PRON- PRP$ cord-006870-f5w6fw6q 1646 20 concerns concern NNS cord-006870-f5w6fw6q 1646 21 . . . cord-006870-f5w6fw6q 1647 1 Subjects subject NNS cord-006870-f5w6fw6q 1647 2 recruited recruit VBN cord-006870-f5w6fw6q 1647 3 from from IN cord-006870-f5w6fw6q 1647 4 a a DT cord-006870-f5w6fw6q 1647 5 probability probability NN cord-006870-f5w6fw6q 1647 6 - - HYPH cord-006870-f5w6fw6q 1647 7 based base VBN cord-006870-f5w6fw6q 1647 8 US US NNP cord-006870-f5w6fw6q 1647 9 population population NN cord-006870-f5w6fw6q 1647 10 sample sample NN cord-006870-f5w6fw6q 1647 11 completed complete VBD cord-006870-f5w6fw6q 1647 12 an an DT cord-006870-f5w6fw6q 1647 13 online online JJ cord-006870-f5w6fw6q 1647 14 best well RBS cord-006870-f5w6fw6q 1647 15 - - HYPH cord-006870-f5w6fw6q 1647 16 worst bad JJS cord-006870-f5w6fw6q 1647 17 survey survey NN cord-006870-f5w6fw6q 1647 18 that that WDT cord-006870-f5w6fw6q 1647 19 presented present VBD cord-006870-f5w6fw6q 1647 20 the the DT cord-006870-f5w6fw6q 1647 21 above above JJ cord-006870-f5w6fw6q 1647 22 scenario scenario NN cord-006870-f5w6fw6q 1647 23 and and CC cord-006870-f5w6fw6q 1647 24 asked ask VBD cord-006870-f5w6fw6q 1647 25 the the DT cord-006870-f5w6fw6q 1647 26 respondent respondent NN cord-006870-f5w6fw6q 1647 27 to to TO cord-006870-f5w6fw6q 1647 28 prioritize prioritize VB cord-006870-f5w6fw6q 1647 29 concerns concern NNS cord-006870-f5w6fw6q 1647 30 as as IN cord-006870-f5w6fw6q 1647 31 the the DT cord-006870-f5w6fw6q 1647 32 patient patient NN cord-006870-f5w6fw6q 1647 33 's 's POS cord-006870-f5w6fw6q 1647 34 surrogate surrogate NN cord-006870-f5w6fw6q 1647 35 . . . cord-006870-f5w6fw6q 1648 1 Clusters cluster NNS cord-006870-f5w6fw6q 1648 2 were be VBD cord-006870-f5w6fw6q 1648 3 identified identify VBN cord-006870-f5w6fw6q 1648 4 with with IN cord-006870-f5w6fw6q 1648 5 latent latent JJ cord-006870-f5w6fw6q 1648 6 class class NN cord-006870-f5w6fw6q 1648 7 analysis analysis NN cord-006870-f5w6fw6q 1648 8 after after IN cord-006870-f5w6fw6q 1648 9 weighting weight VBG cord-006870-f5w6fw6q 1648 10 data datum NNS cord-006870-f5w6fw6q 1648 11 to to TO cord-006870-f5w6fw6q 1648 12 match match VB cord-006870-f5w6fw6q 1648 13 the the DT cord-006870-f5w6fw6q 1648 14 US US NNP cord-006870-f5w6fw6q 1648 15 Census Census NNP cord-006870-f5w6fw6q 1648 16 demographic demographic JJ cord-006870-f5w6fw6q 1648 17 distribution distribution NN cord-006870-f5w6fw6q 1648 18 . . . cord-006870-f5w6fw6q 1649 1 Class class NN cord-006870-f5w6fw6q 1649 2 solutions solution NNS cord-006870-f5w6fw6q 1649 3 were be VBD cord-006870-f5w6fw6q 1649 4 replicated replicate VBN cord-006870-f5w6fw6q 1649 5 20 20 CD cord-006870-f5w6fw6q 1649 6 times time NNS cord-006870-f5w6fw6q 1649 7 from from IN cord-006870-f5w6fw6q 1649 8 random random JJ cord-006870-f5w6fw6q 1649 9 starting starting NN cord-006870-f5w6fw6q 1649 10 seeds seed NNS cord-006870-f5w6fw6q 1649 11 , , , cord-006870-f5w6fw6q 1649 12 with with IN cord-006870-f5w6fw6q 1649 13 the the DT cord-006870-f5w6fw6q 1649 14 solution solution NN cord-006870-f5w6fw6q 1649 15 chosen choose VBN cord-006870-f5w6fw6q 1649 16 after after IN cord-006870-f5w6fw6q 1649 17 factoring factor VBG cord-006870-f5w6fw6q 1649 18 in in IN cord-006870-f5w6fw6q 1649 19 Akaike Akaike NNP cord-006870-f5w6fw6q 1649 20 's 's POS cord-006870-f5w6fw6q 1649 21 information information NN cord-006870-f5w6fw6q 1649 22 criterion criterion NN cord-006870-f5w6fw6q 1649 23 . . . cord-006870-f5w6fw6q 1650 1 We -PRON- PRP cord-006870-f5w6fw6q 1650 2 identified identify VBD cord-006870-f5w6fw6q 1650 3 4 4 CD cord-006870-f5w6fw6q 1650 4 distinct distinct JJ cord-006870-f5w6fw6q 1650 5 decisional decisional JJ cord-006870-f5w6fw6q 1650 6 groups group NNS cord-006870-f5w6fw6q 1650 7 among among IN cord-006870-f5w6fw6q 1650 8 792 792 CD cord-006870-f5w6fw6q 1650 9 respondents respondent NNS cord-006870-f5w6fw6q 1650 10 ( ( -LRB- cord-006870-f5w6fw6q 1650 11 response response NN cord-006870-f5w6fw6q 1650 12 rate rate NN cord-006870-f5w6fw6q 1650 13 = = SYM cord-006870-f5w6fw6q 1650 14 44.6 44.6 CD cord-006870-f5w6fw6q 1650 15 % % NN cord-006870-f5w6fw6q 1650 16 ) ) -RRB- cord-006870-f5w6fw6q 1650 17 . . . cord-006870-f5w6fw6q 1651 1 All all DT cord-006870-f5w6fw6q 1651 2 groups group NNS cord-006870-f5w6fw6q 1651 3 reported report VBD cord-006870-f5w6fw6q 1651 4 multiple multiple JJ cord-006870-f5w6fw6q 1651 5 concerns concern NNS cord-006870-f5w6fw6q 1651 6 as as IN cord-006870-f5w6fw6q 1651 7 important important JJ cord-006870-f5w6fw6q 1651 8 , , , cord-006870-f5w6fw6q 1651 9 but but CC cord-006870-f5w6fw6q 1651 10 Group Group NNP cord-006870-f5w6fw6q 1651 11 1 1 CD cord-006870-f5w6fw6q 1651 12 ( ( -LRB- cord-006870-f5w6fw6q 1651 13 34.4 34.4 CD cord-006870-f5w6fw6q 1651 14 % % NN cord-006870-f5w6fw6q 1651 15 ) ) -RRB- cord-006870-f5w6fw6q 1651 16 was be VBD cord-006870-f5w6fw6q 1651 17 more more RBR cord-006870-f5w6fw6q 1651 18 concerned concerned JJ cord-006870-f5w6fw6q 1651 19 than than IN cord-006870-f5w6fw6q 1651 20 any any DT cord-006870-f5w6fw6q 1651 21 other other JJ cord-006870-f5w6fw6q 1651 22 that that IN cord-006870-f5w6fw6q 1651 23 the the DT cord-006870-f5w6fw6q 1651 24 patient patient NN cord-006870-f5w6fw6q 1651 25 was be VBD cord-006870-f5w6fw6q 1651 26 too too RB cord-006870-f5w6fw6q 1651 27 old old JJ cord-006870-f5w6fw6q 1651 28 to to TO cord-006870-f5w6fw6q 1651 29 live live VB cord-006870-f5w6fw6q 1651 30 with with IN cord-006870-f5w6fw6q 1651 31 disability disability NN cord-006870-f5w6fw6q 1651 32 . . . cord-006870-f5w6fw6q 1652 1 Group group NN cord-006870-f5w6fw6q 1652 2 2 2 CD cord-006870-f5w6fw6q 1652 3 ( ( -LRB- cord-006870-f5w6fw6q 1652 4 26.4 26.4 CD cord-006870-f5w6fw6q 1652 5 % % NN cord-006870-f5w6fw6q 1652 6 ) ) -RRB- cord-006870-f5w6fw6q 1652 7 focused focus VBD cord-006870-f5w6fw6q 1652 8 on on IN cord-006870-f5w6fw6q 1652 9 ensuring ensure VBG cord-006870-f5w6fw6q 1652 10 agreement agreement NN cord-006870-f5w6fw6q 1652 11 among among IN cord-006870-f5w6fw6q 1652 12 other other JJ cord-006870-f5w6fw6q 1652 13 family family NN cord-006870-f5w6fw6q 1652 14 members member NNS cord-006870-f5w6fw6q 1652 15 . . . cord-006870-f5w6fw6q 1653 1 Group group NN cord-006870-f5w6fw6q 1653 2 3 3 CD cord-006870-f5w6fw6q 1653 3 ( ( -LRB- cord-006870-f5w6fw6q 1653 4 20.7 20.7 CD cord-006870-f5w6fw6q 1653 5 % % NN cord-006870-f5w6fw6q 1653 6 ) ) -RRB- cord-006870-f5w6fw6q 1653 7 was be VBD cord-006870-f5w6fw6q 1653 8 concerned concern VBN cord-006870-f5w6fw6q 1653 9 that that IN cord-006870-f5w6fw6q 1653 10 the the DT cord-006870-f5w6fw6q 1653 11 patient patient NN cord-006870-f5w6fw6q 1653 12 might may MD cord-006870-f5w6fw6q 1653 13 suffer suffer VB cord-006870-f5w6fw6q 1653 14 if if IN cord-006870-f5w6fw6q 1653 15 tube tube NN cord-006870-f5w6fw6q 1653 16 feeding feeding NN cord-006870-f5w6fw6q 1653 17 and and CC cord-006870-f5w6fw6q 1653 18 IV IV NNP cord-006870-f5w6fw6q 1653 19 fluids fluid NNS cord-006870-f5w6fw6q 1653 20 were be VBD cord-006870-f5w6fw6q 1653 21 stopped stop VBN cord-006870-f5w6fw6q 1653 22 and and CC cord-006870-f5w6fw6q 1653 23 that that IN cord-006870-f5w6fw6q 1653 24 the the DT cord-006870-f5w6fw6q 1653 25 prognosis prognosis NN cord-006870-f5w6fw6q 1653 26 could could MD cord-006870-f5w6fw6q 1653 27 be be VB cord-006870-f5w6fw6q 1653 28 incorrect incorrect JJ cord-006870-f5w6fw6q 1653 29 . . . cord-006870-f5w6fw6q 1654 1 Group group NN cord-006870-f5w6fw6q 1654 2 4 4 CD cord-006870-f5w6fw6q 1654 3 ( ( -LRB- cord-006870-f5w6fw6q 1654 4 18.6 18.6 CD cord-006870-f5w6fw6q 1654 5 % % NN cord-006870-f5w6fw6q 1654 6 ) ) -RRB- cord-006870-f5w6fw6q 1654 7 had have VBD cord-006870-f5w6fw6q 1654 8 numerous numerous JJ cord-006870-f5w6fw6q 1654 9 considerations consideration NNS cord-006870-f5w6fw6q 1654 10 that that WDT cord-006870-f5w6fw6q 1654 11 were be VBD cord-006870-f5w6fw6q 1654 12 comparably comparably RB cord-006870-f5w6fw6q 1654 13 important important JJ cord-006870-f5w6fw6q 1654 14 but but CC cord-006870-f5w6fw6q 1654 15 prioritized prioritize VBN cord-006870-f5w6fw6q 1654 16 paying pay VBG cord-006870-f5w6fw6q 1654 17 for for IN cord-006870-f5w6fw6q 1654 18 long long JJ cord-006870-f5w6fw6q 1654 19 - - HYPH cord-006870-f5w6fw6q 1654 20 term term NN cord-006870-f5w6fw6q 1654 21 care care NN cord-006870-f5w6fw6q 1654 22 . . . cord-006870-f5w6fw6q 1655 1 Groups group NNS cord-006870-f5w6fw6q 1655 2 varied vary VBN cord-006870-f5w6fw6q 1655 3 in in IN cord-006870-f5w6fw6q 1655 4 whether whether IN cord-006870-f5w6fw6q 1655 5 they -PRON- PRP cord-006870-f5w6fw6q 1655 6 would would MD cord-006870-f5w6fw6q 1655 7 actually actually RB cord-006870-f5w6fw6q 1655 8 request request VB cord-006870-f5w6fw6q 1655 9 prolonging prolong VBG cord-006870-f5w6fw6q 1655 10 care care NN cord-006870-f5w6fw6q 1655 11 for for IN cord-006870-f5w6fw6q 1655 12 the the DT cord-006870-f5w6fw6q 1655 13 patient patient NN cord-006870-f5w6fw6q 1655 14 ( ( -LRB- cord-006870-f5w6fw6q 1655 15 Group group NN cord-006870-f5w6fw6q 1655 16 1 1 CD cord-006870-f5w6fw6q 1655 17 = = SYM cord-006870-f5w6fw6q 1655 18 5.20 5.20 CD cord-006870-f5w6fw6q 1655 19 % % NN cord-006870-f5w6fw6q 1655 20 , , , cord-006870-f5w6fw6q 1655 21 G2 G2 NNP cord-006870-f5w6fw6q 1655 22 = = SYM cord-006870-f5w6fw6q 1655 23 9.46 9.46 CD cord-006870-f5w6fw6q 1655 24 % % NN cord-006870-f5w6fw6q 1655 25 , , , cord-006870-f5w6fw6q 1655 26 G3 G3 NNP cord-006870-f5w6fw6q 1655 27 = = SYM cord-006870-f5w6fw6q 1655 28 31.13 31.13 CD cord-006870-f5w6fw6q 1655 29 % % NN cord-006870-f5w6fw6q 1655 30 , , , cord-006870-f5w6fw6q 1655 31 G4 G4 NNP cord-006870-f5w6fw6q 1655 32 = = SYM cord-006870-f5w6fw6q 1655 33 23.12 23.12 CD cord-006870-f5w6fw6q 1655 34 % % NN cord-006870-f5w6fw6q 1655 35 , , , cord-006870-f5w6fw6q 1655 36 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 1655 37 ) ) -RRB- cord-006870-f5w6fw6q 1655 38 . . . cord-006870-f5w6fw6q 1656 1 In in IN cord-006870-f5w6fw6q 1656 2 a a DT cord-006870-f5w6fw6q 1656 3 multivariate multivariate JJ cord-006870-f5w6fw6q 1656 4 model model NN cord-006870-f5w6fw6q 1656 5 , , , cord-006870-f5w6fw6q 1656 6 religious religious JJ cord-006870-f5w6fw6q 1656 7 affiliation affiliation NN cord-006870-f5w6fw6q 1656 8 and and CC cord-006870-f5w6fw6q 1656 9 frequency frequency NN cord-006870-f5w6fw6q 1656 10 of of IN cord-006870-f5w6fw6q 1656 11 attending attend VBG cord-006870-f5w6fw6q 1656 12 religious religious JJ cord-006870-f5w6fw6q 1656 13 services service NNS cord-006870-f5w6fw6q 1656 14 were be VBD cord-006870-f5w6fw6q 1656 15 the the DT cord-006870-f5w6fw6q 1656 16 only only JJ cord-006870-f5w6fw6q 1656 17 variables variable NNS cord-006870-f5w6fw6q 1656 18 independently independently RB cord-006870-f5w6fw6q 1656 19 predicting predict VBG cord-006870-f5w6fw6q 1656 20 group group NN cord-006870-f5w6fw6q 1656 21 membership membership NN cord-006870-f5w6fw6q 1656 22 . . . cord-006870-f5w6fw6q 1657 1 We -PRON- PRP cord-006870-f5w6fw6q 1657 2 identified identify VBD cord-006870-f5w6fw6q 1657 3 4 4 CD cord-006870-f5w6fw6q 1657 4 distinct distinct JJ cord-006870-f5w6fw6q 1657 5 profiles profile NNS cord-006870-f5w6fw6q 1657 6 of of IN cord-006870-f5w6fw6q 1657 7 decisional decisional JJ cord-006870-f5w6fw6q 1657 8 patterns pattern NNS cord-006870-f5w6fw6q 1657 9 for for IN cord-006870-f5w6fw6q 1657 10 surrogates surrogate NNS cord-006870-f5w6fw6q 1657 11 of of IN cord-006870-f5w6fw6q 1657 12 severe severe JJ cord-006870-f5w6fw6q 1657 13 ICH ICH NNP cord-006870-f5w6fw6q 1657 14 patients patient NNS cord-006870-f5w6fw6q 1657 15 with with IN cord-006870-f5w6fw6q 1657 16 uncertain uncertain JJ cord-006870-f5w6fw6q 1657 17 prognosis prognosis NN cord-006870-f5w6fw6q 1657 18 . . . cord-006870-f5w6fw6q 1658 1 These these DT cord-006870-f5w6fw6q 1658 2 data datum NNS cord-006870-f5w6fw6q 1658 3 will will MD cord-006870-f5w6fw6q 1658 4 inform inform VB cord-006870-f5w6fw6q 1658 5 development development NN cord-006870-f5w6fw6q 1658 6 of of IN cord-006870-f5w6fw6q 1658 7 strategically strategically RB cord-006870-f5w6fw6q 1658 8 tailored tailor VBN cord-006870-f5w6fw6q 1658 9 decision decision NN cord-006870-f5w6fw6q 1658 10 aids aids NNP cord-006870-f5w6fw6q 1658 11 . . . cord-006870-f5w6fw6q 1659 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 1659 2 venous venous JJ cord-006870-f5w6fw6q 1659 3 sinus sinus NN cord-006870-f5w6fw6q 1659 4 thrombosis thrombosis NN cord-006870-f5w6fw6q 1659 5 ( ( -LRB- cord-006870-f5w6fw6q 1659 6 CVST CVST NNP cord-006870-f5w6fw6q 1659 7 ) ) -RRB- cord-006870-f5w6fw6q 1659 8 represents represent VBZ cord-006870-f5w6fw6q 1659 9 an an DT cord-006870-f5w6fw6q 1659 10 important important JJ cord-006870-f5w6fw6q 1659 11 cause cause NN cord-006870-f5w6fw6q 1659 12 of of IN cord-006870-f5w6fw6q 1659 13 both both CC cord-006870-f5w6fw6q 1659 14 ischemic ischemic JJ cord-006870-f5w6fw6q 1659 15 and and CC cord-006870-f5w6fw6q 1659 16 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1659 17 strokes stroke NNS cord-006870-f5w6fw6q 1659 18 in in IN cord-006870-f5w6fw6q 1659 19 young young JJ cord-006870-f5w6fw6q 1659 20 people people NNS cord-006870-f5w6fw6q 1659 21 . . . cord-006870-f5w6fw6q 1660 1 While while IN cord-006870-f5w6fw6q 1660 2 recent recent JJ cord-006870-f5w6fw6q 1660 3 guidelines guideline NNS cord-006870-f5w6fw6q 1660 4 recommend recommend VBP cord-006870-f5w6fw6q 1660 5 management management NN cord-006870-f5w6fw6q 1660 6 in in IN cord-006870-f5w6fw6q 1660 7 a a DT cord-006870-f5w6fw6q 1660 8 stroke stroke NN cord-006870-f5w6fw6q 1660 9 unit unit NN cord-006870-f5w6fw6q 1660 10 , , , cord-006870-f5w6fw6q 1660 11 the the DT cord-006870-f5w6fw6q 1660 12 impact impact NN cord-006870-f5w6fw6q 1660 13 of of IN cord-006870-f5w6fw6q 1660 14 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 1660 15 care care NN cord-006870-f5w6fw6q 1660 16 in in IN cord-006870-f5w6fw6q 1660 17 this this DT cord-006870-f5w6fw6q 1660 18 condition condition NN cord-006870-f5w6fw6q 1660 19 has have VBZ cord-006870-f5w6fw6q 1660 20 not not RB cord-006870-f5w6fw6q 1660 21 been be VBN cord-006870-f5w6fw6q 1660 22 studied study VBN cord-006870-f5w6fw6q 1660 23 . . . cord-006870-f5w6fw6q 1661 1 We -PRON- PRP cord-006870-f5w6fw6q 1661 2 aimed aim VBD cord-006870-f5w6fw6q 1661 3 to to TO cord-006870-f5w6fw6q 1661 4 assess assess VB cord-006870-f5w6fw6q 1661 5 whether whether IN cord-006870-f5w6fw6q 1661 6 the the DT cord-006870-f5w6fw6q 1661 7 introduction introduction NN cord-006870-f5w6fw6q 1661 8 of of IN cord-006870-f5w6fw6q 1661 9 a a DT cord-006870-f5w6fw6q 1661 10 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 1661 11 Care Care NNP cord-006870-f5w6fw6q 1661 12 program program NN cord-006870-f5w6fw6q 1661 13 influenced influence VBD cord-006870-f5w6fw6q 1661 14 clinical clinical JJ cord-006870-f5w6fw6q 1661 15 outcomes outcome NNS cord-006870-f5w6fw6q 1661 16 in in IN cord-006870-f5w6fw6q 1661 17 CVST CVST NNP cord-006870-f5w6fw6q 1661 18 patients patient NNS cord-006870-f5w6fw6q 1661 19 . . . cord-006870-f5w6fw6q 1662 1 We -PRON- PRP cord-006870-f5w6fw6q 1662 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 1662 3 reviewed review VBD cord-006870-f5w6fw6q 1662 4 electronic electronic JJ cord-006870-f5w6fw6q 1662 5 medical medical JJ cord-006870-f5w6fw6q 1662 6 records record NNS cord-006870-f5w6fw6q 1662 7 of of IN cord-006870-f5w6fw6q 1662 8 adult adult NN cord-006870-f5w6fw6q 1662 9 patients patient NNS cord-006870-f5w6fw6q 1662 10 admitted admit VBN cord-006870-f5w6fw6q 1662 11 to to IN cord-006870-f5w6fw6q 1662 12 Yale Yale NNP cord-006870-f5w6fw6q 1662 13 New New NNP cord-006870-f5w6fw6q 1662 14 Haven Haven NNP cord-006870-f5w6fw6q 1662 15 Hospital Hospital NNP cord-006870-f5w6fw6q 1662 16 's 's POS cord-006870-f5w6fw6q 1662 17 Neuroscience Neuroscience NNP cord-006870-f5w6fw6q 1662 18 ICU ICU NNP cord-006870-f5w6fw6q 1662 19 ( ( -LRB- cord-006870-f5w6fw6q 1662 20 NICU NICU NNP cord-006870-f5w6fw6q 1662 21 ) ) -RRB- cord-006870-f5w6fw6q 1662 22 between between IN cord-006870-f5w6fw6q 1662 23 2011 2011 CD cord-006870-f5w6fw6q 1662 24 and and CC cord-006870-f5w6fw6q 1662 25 2017 2017 CD cord-006870-f5w6fw6q 1662 26 with with IN cord-006870-f5w6fw6q 1662 27 a a DT cord-006870-f5w6fw6q 1662 28 diagnosis diagnosis NN cord-006870-f5w6fw6q 1662 29 of of IN cord-006870-f5w6fw6q 1662 30 CVST CVST NNP cord-006870-f5w6fw6q 1662 31 . . . cord-006870-f5w6fw6q 1663 1 Demographics demographic NNS cord-006870-f5w6fw6q 1663 2 , , , cord-006870-f5w6fw6q 1663 3 vascular vascular JJ cord-006870-f5w6fw6q 1663 4 risk risk NN cord-006870-f5w6fw6q 1663 5 factors factor NNS cord-006870-f5w6fw6q 1663 6 , , , cord-006870-f5w6fw6q 1663 7 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 1663 8 , , , cord-006870-f5w6fw6q 1663 9 length length NN cord-006870-f5w6fw6q 1663 10 of of IN cord-006870-f5w6fw6q 1663 11 stay stay NN cord-006870-f5w6fw6q 1663 12 and and CC cord-006870-f5w6fw6q 1663 13 discharge discharge NN cord-006870-f5w6fw6q 1663 14 modified modify VBN cord-006870-f5w6fw6q 1663 15 Rankin Rankin NNP cord-006870-f5w6fw6q 1663 16 scale scale NN cord-006870-f5w6fw6q 1663 17 ( ( -LRB- cord-006870-f5w6fw6q 1663 18 mRS mRS : cord-006870-f5w6fw6q 1663 19 ) ) -RRB- cord-006870-f5w6fw6q 1663 20 were be VBD cord-006870-f5w6fw6q 1663 21 collected collect VBN cord-006870-f5w6fw6q 1663 22 . . . cord-006870-f5w6fw6q 1664 1 Patients patient NNS cord-006870-f5w6fw6q 1664 2 were be VBD cord-006870-f5w6fw6q 1664 3 excluded exclude VBN cord-006870-f5w6fw6q 1664 4 for for IN cord-006870-f5w6fw6q 1664 5 age age NN cord-006870-f5w6fw6q 1664 6 24 24 CD cord-006870-f5w6fw6q 1664 7 hours hour NNS cord-006870-f5w6fw6q 1664 8 of of IN cord-006870-f5w6fw6q 1664 9 presentation presentation NN cord-006870-f5w6fw6q 1664 10 . . . cord-006870-f5w6fw6q 1665 1 We -PRON- PRP cord-006870-f5w6fw6q 1665 2 compared compare VBD cord-006870-f5w6fw6q 1665 3 two two CD cord-006870-f5w6fw6q 1665 4 time time NN cord-006870-f5w6fw6q 1665 5 periods period NNS cord-006870-f5w6fw6q 1665 6 , , , cord-006870-f5w6fw6q 1665 7 before before IN cord-006870-f5w6fw6q 1665 8 ( ( -LRB- cord-006870-f5w6fw6q 1665 9 epoch epoch NN cord-006870-f5w6fw6q 1665 10 1 1 CD cord-006870-f5w6fw6q 1665 11 , , , cord-006870-f5w6fw6q 1665 12 2010 2010 CD cord-006870-f5w6fw6q 1665 13 - - SYM cord-006870-f5w6fw6q 1665 14 2012 2012 CD cord-006870-f5w6fw6q 1665 15 ) ) -RRB- cord-006870-f5w6fw6q 1665 16 and and CC cord-006870-f5w6fw6q 1665 17 after after IN cord-006870-f5w6fw6q 1665 18 ( ( -LRB- cord-006870-f5w6fw6q 1665 19 epoch epoch NN cord-006870-f5w6fw6q 1665 20 2 2 CD cord-006870-f5w6fw6q 1665 21 , , , cord-006870-f5w6fw6q 1665 22 2013 2013 CD cord-006870-f5w6fw6q 1665 23 - - SYM cord-006870-f5w6fw6q 1665 24 2017 2017 CD cord-006870-f5w6fw6q 1665 25 ) ) -RRB- cord-006870-f5w6fw6q 1665 26 the the DT cord-006870-f5w6fw6q 1665 27 introduction introduction NN cord-006870-f5w6fw6q 1665 28 of of IN cord-006870-f5w6fw6q 1665 29 continuous continuous JJ cord-006870-f5w6fw6q 1665 30 staffing staffing NN cord-006870-f5w6fw6q 1665 31 of of IN cord-006870-f5w6fw6q 1665 32 CVST CVST NNP cord-006870-f5w6fw6q 1665 33 cases case NNS cord-006870-f5w6fw6q 1665 34 by by IN cord-006870-f5w6fw6q 1665 35 neurointensivists neurointensivist NNS cord-006870-f5w6fw6q 1665 36 in in IN cord-006870-f5w6fw6q 1665 37 the the DT cord-006870-f5w6fw6q 1665 38 NICU NICU NNP cord-006870-f5w6fw6q 1665 39 . . . cord-006870-f5w6fw6q 1666 1 Univariable univariable JJ cord-006870-f5w6fw6q 1666 2 and and CC cord-006870-f5w6fw6q 1666 3 multivariable multivariable JJ cord-006870-f5w6fw6q 1666 4 logistic logistic JJ cord-006870-f5w6fw6q 1666 5 regression regression NN cord-006870-f5w6fw6q 1666 6 were be VBD cord-006870-f5w6fw6q 1666 7 utilized utilize VBN cord-006870-f5w6fw6q 1666 8 to to TO cord-006870-f5w6fw6q 1666 9 model model VB cord-006870-f5w6fw6q 1666 10 the the DT cord-006870-f5w6fw6q 1666 11 odds odd NNS cord-006870-f5w6fw6q 1666 12 of of IN cord-006870-f5w6fw6q 1666 13 poor poor JJ cord-006870-f5w6fw6q 1666 14 outcome outcome NN cord-006870-f5w6fw6q 1666 15 ( ( -LRB- cord-006870-f5w6fw6q 1666 16 dichotomized dichotomize VBN cord-006870-f5w6fw6q 1666 17 mRS mrs PRP$ cord-006870-f5w6fw6q 1666 18 0 0 CD cord-006870-f5w6fw6q 1666 19 - - SYM cord-006870-f5w6fw6q 1666 20 2 2 CD cord-006870-f5w6fw6q 1666 21 vs vs IN cord-006870-f5w6fw6q 1666 22 3 3 CD cord-006870-f5w6fw6q 1666 23 - - SYM cord-006870-f5w6fw6q 1666 24 6 6 CD cord-006870-f5w6fw6q 1666 25 ) ) -RRB- cord-006870-f5w6fw6q 1666 26 . . . cord-006870-f5w6fw6q 1667 1 Fifty fifty CD cord-006870-f5w6fw6q 1667 2 - - HYPH cord-006870-f5w6fw6q 1667 3 three three CD cord-006870-f5w6fw6q 1667 4 patients patient NNS cord-006870-f5w6fw6q 1667 5 with with IN cord-006870-f5w6fw6q 1667 6 CVST CVST NNP cord-006870-f5w6fw6q 1667 7 met meet VBD cord-006870-f5w6fw6q 1667 8 the the DT cord-006870-f5w6fw6q 1667 9 inclusion inclusion NN cord-006870-f5w6fw6q 1667 10 criteria criterion NNS cord-006870-f5w6fw6q 1667 11 during during IN cord-006870-f5w6fw6q 1667 12 the the DT cord-006870-f5w6fw6q 1667 13 study study NN cord-006870-f5w6fw6q 1667 14 period period NN cord-006870-f5w6fw6q 1667 15 ( ( -LRB- cord-006870-f5w6fw6q 1667 16 mean mean UH cord-006870-f5w6fw6q 1667 17 age age NN cord-006870-f5w6fw6q 1667 18 39 39 CD cord-006870-f5w6fw6q 1668 1 ( ( -LRB- cord-006870-f5w6fw6q 1668 2 + + CC cord-006870-f5w6fw6q 1668 3 /-17 /-17 NFP cord-006870-f5w6fw6q 1668 4 ) ) -RRB- cord-006870-f5w6fw6q 1668 5 years year NNS cord-006870-f5w6fw6q 1668 6 , , , cord-006870-f5w6fw6q 1668 7 51 51 CD cord-006870-f5w6fw6q 1668 8 % % NN cord-006870-f5w6fw6q 1668 9 female female NN cord-006870-f5w6fw6q 1668 10 ) ) -RRB- cord-006870-f5w6fw6q 1668 11 . . . cord-006870-f5w6fw6q 1669 1 20 20 CD cord-006870-f5w6fw6q 1669 2 patients patient NNS cord-006870-f5w6fw6q 1669 3 were be VBD cord-006870-f5w6fw6q 1669 4 identified identify VBN cord-006870-f5w6fw6q 1669 5 for for IN cord-006870-f5w6fw6q 1669 6 Epoch Epoch NNP cord-006870-f5w6fw6q 1669 7 1 1 CD cord-006870-f5w6fw6q 1669 8 and and CC cord-006870-f5w6fw6q 1669 9 33 33 CD cord-006870-f5w6fw6q 1669 10 patients patient NNS cord-006870-f5w6fw6q 1669 11 for for IN cord-006870-f5w6fw6q 1669 12 Epoch Epoch NNP cord-006870-f5w6fw6q 1669 13 2 2 CD cord-006870-f5w6fw6q 1669 14 . . . cord-006870-f5w6fw6q 1670 1 Overall overall RB cord-006870-f5w6fw6q 1670 2 , , , cord-006870-f5w6fw6q 1670 3 40 40 CD cord-006870-f5w6fw6q 1670 4 patients patient NNS cord-006870-f5w6fw6q 1670 5 ( ( -LRB- cord-006870-f5w6fw6q 1670 6 76 76 CD cord-006870-f5w6fw6q 1670 7 % % NN cord-006870-f5w6fw6q 1670 8 ) ) -RRB- cord-006870-f5w6fw6q 1670 9 had have VBD cord-006870-f5w6fw6q 1670 10 a a DT cord-006870-f5w6fw6q 1670 11 good good JJ cord-006870-f5w6fw6q 1670 12 ( ( -LRB- cord-006870-f5w6fw6q 1670 13 mRS mrs PRP$ cord-006870-f5w6fw6q 1670 14 0 0 CD cord-006870-f5w6fw6q 1670 15 - - SYM cord-006870-f5w6fw6q 1670 16 2 2 CD cord-006870-f5w6fw6q 1670 17 ) ) -RRB- cord-006870-f5w6fw6q 1670 18 outcome outcome NN cord-006870-f5w6fw6q 1670 19 . . . cord-006870-f5w6fw6q 1671 1 For for IN cord-006870-f5w6fw6q 1671 2 epochs epoch NNS cord-006870-f5w6fw6q 1671 3 1 1 CD cord-006870-f5w6fw6q 1671 4 and and CC cord-006870-f5w6fw6q 1671 5 2 2 CD cord-006870-f5w6fw6q 1671 6 , , , cord-006870-f5w6fw6q 1671 7 good good JJ cord-006870-f5w6fw6q 1671 8 outcomes outcome NNS cord-006870-f5w6fw6q 1671 9 were be VBD cord-006870-f5w6fw6q 1671 10 observed observe VBN cord-006870-f5w6fw6q 1671 11 in in IN cord-006870-f5w6fw6q 1671 12 12 12 CD cord-006870-f5w6fw6q 1671 13 ( ( -LRB- cord-006870-f5w6fw6q 1671 14 60 60 CD cord-006870-f5w6fw6q 1671 15 % % NN cord-006870-f5w6fw6q 1671 16 ) ) -RRB- cord-006870-f5w6fw6q 1671 17 and and CC cord-006870-f5w6fw6q 1671 18 28 28 CD cord-006870-f5w6fw6q 1671 19 ( ( -LRB- cord-006870-f5w6fw6q 1671 20 85 85 CD cord-006870-f5w6fw6q 1671 21 % % NN cord-006870-f5w6fw6q 1671 22 ) ) -RRB- cord-006870-f5w6fw6q 1671 23 patients patient NNS cord-006870-f5w6fw6q 1671 24 , , , cord-006870-f5w6fw6q 1671 25 respectively respectively RB cord-006870-f5w6fw6q 1671 26 ( ( -LRB- cord-006870-f5w6fw6q 1671 27 p=0.04 p=0.04 NN cord-006870-f5w6fw6q 1671 28 ) ) -RRB- cord-006870-f5w6fw6q 1671 29 . . . cord-006870-f5w6fw6q 1672 1 In in IN cord-006870-f5w6fw6q 1672 2 both both DT cord-006870-f5w6fw6q 1672 3 univariable univariable JJ cord-006870-f5w6fw6q 1672 4 and and CC cord-006870-f5w6fw6q 1672 5 multivariable multivariable JJ cord-006870-f5w6fw6q 1672 6 regression regression NN cord-006870-f5w6fw6q 1672 7 analysis analysis NN cord-006870-f5w6fw6q 1672 8 ( ( -LRB- cord-006870-f5w6fw6q 1672 9 adjusted adjust VBN cord-006870-f5w6fw6q 1672 10 for for IN cord-006870-f5w6fw6q 1672 11 age age NN cord-006870-f5w6fw6q 1672 12 and and CC cord-006870-f5w6fw6q 1672 13 sex sex NN cord-006870-f5w6fw6q 1672 14 ) ) -RRB- cord-006870-f5w6fw6q 1672 15 , , , cord-006870-f5w6fw6q 1672 16 admission admission NN cord-006870-f5w6fw6q 1672 17 during during IN cord-006870-f5w6fw6q 1672 18 epoch epoch NN cord-006870-f5w6fw6q 1672 19 2 2 CD cord-006870-f5w6fw6q 1672 20 was be VBD cord-006870-f5w6fw6q 1672 21 associated associate VBN cord-006870-f5w6fw6q 1672 22 with with IN cord-006870-f5w6fw6q 1672 23 a a DT cord-006870-f5w6fw6q 1672 24 significantly significantly RB cord-006870-f5w6fw6q 1672 25 reduced reduce VBN cord-006870-f5w6fw6q 1672 26 odds odd NNS cord-006870-f5w6fw6q 1672 27 of of IN cord-006870-f5w6fw6q 1672 28 a a DT cord-006870-f5w6fw6q 1672 29 poor poor JJ cord-006870-f5w6fw6q 1672 30 outcome outcome NN cord-006870-f5w6fw6q 1672 31 ( ( -LRB- cord-006870-f5w6fw6q 1672 32 OR or CC cord-006870-f5w6fw6q 1672 33 0.27 0.27 CD cord-006870-f5w6fw6q 1672 34 , , , cord-006870-f5w6fw6q 1672 35 CI CI NNP cord-006870-f5w6fw6q 1672 36 0.07 0.07 CD cord-006870-f5w6fw6q 1672 37 -0.98 -0.98 CD cord-006870-f5w6fw6q 1672 38 ; ; : cord-006870-f5w6fw6q 1672 39 p p NN cord-006870-f5w6fw6q 1672 40 = = SYM cord-006870-f5w6fw6q 1672 41 0.048 0.048 CD cord-006870-f5w6fw6q 1672 42 ) ) -RRB- cord-006870-f5w6fw6q 1672 43 and and CC cord-006870-f5w6fw6q 1672 44 ( ( -LRB- cord-006870-f5w6fw6q 1672 45 OR or CC cord-006870-f5w6fw6q 1672 46 0.27 0.27 CD cord-006870-f5w6fw6q 1672 47 , , , cord-006870-f5w6fw6q 1672 48 CI CI NNP cord-006870-f5w6fw6q 1672 49 0.07 0.07 CD cord-006870-f5w6fw6q 1672 50 - - SYM cord-006870-f5w6fw6q 1672 51 1 1 CD cord-006870-f5w6fw6q 1672 52 ; ; : cord-006870-f5w6fw6q 1672 53 p=0.05 p=0.05 JJ cord-006870-f5w6fw6q 1672 54 ) ) -RRB- cord-006870-f5w6fw6q 1672 55 , , , cord-006870-f5w6fw6q 1672 56 respectively respectively RB cord-006870-f5w6fw6q 1672 57 . . . cord-006870-f5w6fw6q 1673 1 In in IN cord-006870-f5w6fw6q 1673 2 this this DT cord-006870-f5w6fw6q 1673 3 small small JJ cord-006870-f5w6fw6q 1673 4 , , , cord-006870-f5w6fw6q 1673 5 single single JJ cord-006870-f5w6fw6q 1673 6 - - HYPH cord-006870-f5w6fw6q 1673 7 center center NN cord-006870-f5w6fw6q 1673 8 cohort cohort NN cord-006870-f5w6fw6q 1673 9 of of IN cord-006870-f5w6fw6q 1673 10 patients patient NNS cord-006870-f5w6fw6q 1673 11 with with IN cord-006870-f5w6fw6q 1673 12 CVST CVST NNP cord-006870-f5w6fw6q 1673 13 , , , cord-006870-f5w6fw6q 1673 14 most most JJS cord-006870-f5w6fw6q 1673 15 patients patient NNS cord-006870-f5w6fw6q 1673 16 experienced experience VBD cord-006870-f5w6fw6q 1673 17 a a DT cord-006870-f5w6fw6q 1673 18 good good JJ cord-006870-f5w6fw6q 1673 19 outcome outcome NN cord-006870-f5w6fw6q 1673 20 . . . cord-006870-f5w6fw6q 1674 1 The the DT cord-006870-f5w6fw6q 1674 2 institution institution NN cord-006870-f5w6fw6q 1674 3 of of IN cord-006870-f5w6fw6q 1674 4 continuous continuous JJ cord-006870-f5w6fw6q 1674 5 neurointensivist neurointensivist JJ cord-006870-f5w6fw6q 1674 6 coverage coverage NN cord-006870-f5w6fw6q 1674 7 was be VBD cord-006870-f5w6fw6q 1674 8 independently independently RB cord-006870-f5w6fw6q 1674 9 associated associate VBN cord-006870-f5w6fw6q 1674 10 with with IN cord-006870-f5w6fw6q 1674 11 better well JJR cord-006870-f5w6fw6q 1674 12 outcomes outcome NNS cord-006870-f5w6fw6q 1674 13 . . . cord-006870-f5w6fw6q 1675 1 Further further JJ cord-006870-f5w6fw6q 1675 2 validation validation NN cord-006870-f5w6fw6q 1675 3 in in IN cord-006870-f5w6fw6q 1675 4 prospective prospective JJ cord-006870-f5w6fw6q 1675 5 , , , cord-006870-f5w6fw6q 1675 6 multicenter multicenter JJ cord-006870-f5w6fw6q 1675 7 cohort cohort NN cord-006870-f5w6fw6q 1675 8 studies study NNS cord-006870-f5w6fw6q 1675 9 is be VBZ cord-006870-f5w6fw6q 1675 10 needed need VBN cord-006870-f5w6fw6q 1675 11 . . . cord-006870-f5w6fw6q 1676 1 Thrombelastography Thrombelastography NNP cord-006870-f5w6fw6q 1676 2 ( ( -LRB- cord-006870-f5w6fw6q 1676 3 TEG TEG NNP cord-006870-f5w6fw6q 1676 4 ) ) -RRB- cord-006870-f5w6fw6q 1676 5 provides provide VBZ cord-006870-f5w6fw6q 1676 6 a a DT cord-006870-f5w6fw6q 1676 7 dynamic dynamic JJ cord-006870-f5w6fw6q 1676 8 assessment assessment NN cord-006870-f5w6fw6q 1676 9 of of IN cord-006870-f5w6fw6q 1676 10 clot clot NN cord-006870-f5w6fw6q 1676 11 formation formation NN cord-006870-f5w6fw6q 1676 12 , , , cord-006870-f5w6fw6q 1676 13 strength strength NN cord-006870-f5w6fw6q 1676 14 , , , cord-006870-f5w6fw6q 1676 15 and and CC cord-006870-f5w6fw6q 1676 16 stability stability NN cord-006870-f5w6fw6q 1676 17 . . . cord-006870-f5w6fw6q 1677 1 We -PRON- PRP cord-006870-f5w6fw6q 1677 2 examined examine VBD cord-006870-f5w6fw6q 1677 3 relationships relationship NNS cord-006870-f5w6fw6q 1677 4 between between IN cord-006870-f5w6fw6q 1677 5 TEG TEG NNP cord-006870-f5w6fw6q 1677 6 parameters parameter NNS cord-006870-f5w6fw6q 1677 7 and and CC cord-006870-f5w6fw6q 1677 8 outcomes outcome NNS cord-006870-f5w6fw6q 1677 9 from from IN cord-006870-f5w6fw6q 1677 10 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1677 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1677 12 ( ( -LRB- cord-006870-f5w6fw6q 1677 13 ICH ICH NNP cord-006870-f5w6fw6q 1677 14 ) ) -RRB- cord-006870-f5w6fw6q 1677 15 . . . cord-006870-f5w6fw6q 1678 1 We -PRON- PRP cord-006870-f5w6fw6q 1678 2 prospectively prospectively RB cord-006870-f5w6fw6q 1678 3 enrolled enrol VBD cord-006870-f5w6fw6q 1678 4 patients patient NNS cord-006870-f5w6fw6q 1678 5 with with IN cord-006870-f5w6fw6q 1678 6 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1678 7 ICH ICH NNP cord-006870-f5w6fw6q 1678 8 between between IN cord-006870-f5w6fw6q 1678 9 2009 2009 CD cord-006870-f5w6fw6q 1678 10 to to IN cord-006870-f5w6fw6q 1678 11 2017 2017 CD cord-006870-f5w6fw6q 1678 12 . . . cord-006870-f5w6fw6q 1679 1 TEG TEG NNP cord-006870-f5w6fw6q 1679 2 was be VBD cord-006870-f5w6fw6q 1679 3 performed perform VBN cord-006870-f5w6fw6q 1679 4 at at IN cord-006870-f5w6fw6q 1679 5 the the DT cord-006870-f5w6fw6q 1679 6 time time NN cord-006870-f5w6fw6q 1679 7 of of IN cord-006870-f5w6fw6q 1679 8 admission admission NN cord-006870-f5w6fw6q 1679 9 . . . cord-006870-f5w6fw6q 1680 1 We -PRON- PRP cord-006870-f5w6fw6q 1680 2 divided divide VBD cord-006870-f5w6fw6q 1680 3 patients patient NNS cord-006870-f5w6fw6q 1680 4 into into IN cord-006870-f5w6fw6q 1680 5 two two CD cord-006870-f5w6fw6q 1680 6 groups group NNS cord-006870-f5w6fw6q 1680 7 based base VBN cord-006870-f5w6fw6q 1680 8 on on IN cord-006870-f5w6fw6q 1680 9 the the DT cord-006870-f5w6fw6q 1680 10 presence presence NN cord-006870-f5w6fw6q 1680 11 or or CC cord-006870-f5w6fw6q 1680 12 absence absence NN cord-006870-f5w6fw6q 1680 13 of of IN cord-006870-f5w6fw6q 1680 14 hematoma hematoma NN cord-006870-f5w6fw6q 1680 15 expansion expansion NN cord-006870-f5w6fw6q 1680 16 ( ( -LRB- cord-006870-f5w6fw6q 1680 17 HE HE NNP cord-006870-f5w6fw6q 1680 18 ) ) -RRB- cord-006870-f5w6fw6q 1680 19 . . . cord-006870-f5w6fw6q 1681 1 Clinical clinical JJ cord-006870-f5w6fw6q 1681 2 characteristics characteristic NNS cord-006870-f5w6fw6q 1681 3 , , , cord-006870-f5w6fw6q 1681 4 baseline baseline JJ cord-006870-f5w6fw6q 1681 5 TEG TEG NNP cord-006870-f5w6fw6q 1681 6 values value NNS cord-006870-f5w6fw6q 1681 7 , , , cord-006870-f5w6fw6q 1681 8 and and CC cord-006870-f5w6fw6q 1681 9 outcomes outcome NNS cord-006870-f5w6fw6q 1681 10 were be VBD cord-006870-f5w6fw6q 1681 11 compared compare VBN cord-006870-f5w6fw6q 1681 12 between between IN cord-006870-f5w6fw6q 1681 13 the the DT cord-006870-f5w6fw6q 1681 14 two two CD cord-006870-f5w6fw6q 1681 15 groups group NNS cord-006870-f5w6fw6q 1681 16 . . . cord-006870-f5w6fw6q 1682 1 Multivariable multivariable JJ cord-006870-f5w6fw6q 1682 2 regression regression NN cord-006870-f5w6fw6q 1682 3 analysis analysis NN cord-006870-f5w6fw6q 1682 4 was be VBD cord-006870-f5w6fw6q 1682 5 conducted conduct VBN cord-006870-f5w6fw6q 1682 6 to to TO cord-006870-f5w6fw6q 1682 7 compare compare VB cord-006870-f5w6fw6q 1682 8 the the DT cord-006870-f5w6fw6q 1682 9 differences difference NNS cord-006870-f5w6fw6q 1682 10 of of IN cord-006870-f5w6fw6q 1682 11 TEG TEG NNP cord-006870-f5w6fw6q 1682 12 components component NNS cord-006870-f5w6fw6q 1682 13 between between IN cord-006870-f5w6fw6q 1682 14 the the DT cord-006870-f5w6fw6q 1682 15 two two CD cord-006870-f5w6fw6q 1682 16 groups group NNS cord-006870-f5w6fw6q 1682 17 after after IN cord-006870-f5w6fw6q 1682 18 adjusting adjust VBG cord-006870-f5w6fw6q 1682 19 for for IN cord-006870-f5w6fw6q 1682 20 potential potential JJ cord-006870-f5w6fw6q 1682 21 confounding confounding JJ cord-006870-f5w6fw6q 1682 22 effects effect NNS cord-006870-f5w6fw6q 1682 23 . . . cord-006870-f5w6fw6q 1683 1 We -PRON- PRP cord-006870-f5w6fw6q 1683 2 included include VBD cord-006870-f5w6fw6q 1683 3 275 275 CD cord-006870-f5w6fw6q 1683 4 patients patient NNS cord-006870-f5w6fw6q 1683 5 , , , cord-006870-f5w6fw6q 1683 6 67 67 CD cord-006870-f5w6fw6q 1683 7 ( ( -LRB- cord-006870-f5w6fw6q 1683 8 24 24 CD cord-006870-f5w6fw6q 1683 9 % % NN cord-006870-f5w6fw6q 1683 10 ) ) -RRB- cord-006870-f5w6fw6q 1683 11 with with IN cord-006870-f5w6fw6q 1683 12 HE HE NNP cord-006870-f5w6fw6q 1683 13 and and CC cord-006870-f5w6fw6q 1683 14 210 210 CD cord-006870-f5w6fw6q 1683 15 ( ( -LRB- cord-006870-f5w6fw6q 1683 16 76 76 CD cord-006870-f5w6fw6q 1683 17 % % NN cord-006870-f5w6fw6q 1683 18 ) ) -RRB- cord-006870-f5w6fw6q 1683 19 without without IN cord-006870-f5w6fw6q 1683 20 HE he PRP cord-006870-f5w6fw6q 1683 21 . . . cord-006870-f5w6fw6q 1684 1 Patients patient NNS cord-006870-f5w6fw6q 1684 2 with with IN cord-006870-f5w6fw6q 1684 3 HE he PRP cord-006870-f5w6fw6q 1684 4 were be VBD cord-006870-f5w6fw6q 1684 5 more more RBR cord-006870-f5w6fw6q 1684 6 often often RB cord-006870-f5w6fw6q 1684 7 male male JJ cord-006870-f5w6fw6q 1684 8 and and CC cord-006870-f5w6fw6q 1684 9 had have VBD cord-006870-f5w6fw6q 1684 10 higher high JJR cord-006870-f5w6fw6q 1684 11 rates rate NNS cord-006870-f5w6fw6q 1684 12 of of IN cord-006870-f5w6fw6q 1684 13 aspirin aspirin NN cord-006870-f5w6fw6q 1684 14 use use NN cord-006870-f5w6fw6q 1684 15 , , , cord-006870-f5w6fw6q 1684 16 lower low JJR cord-006870-f5w6fw6q 1684 17 incidence incidence NN cord-006870-f5w6fw6q 1684 18 of of IN cord-006870-f5w6fw6q 1684 19 intraventricular intraventricular JJ cord-006870-f5w6fw6q 1684 20 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1684 21 , , , cord-006870-f5w6fw6q 1684 22 and and CC cord-006870-f5w6fw6q 1684 23 larger large JJR cord-006870-f5w6fw6q 1684 24 baseline baseline JJ cord-006870-f5w6fw6q 1684 25 hematoma hematoma NN cord-006870-f5w6fw6q 1684 26 volumes volume NNS cord-006870-f5w6fw6q 1684 27 . . . cord-006870-f5w6fw6q 1685 1 After after IN cord-006870-f5w6fw6q 1685 2 controlling control VBG cord-006870-f5w6fw6q 1685 3 for for IN cord-006870-f5w6fw6q 1685 4 potential potential JJ cord-006870-f5w6fw6q 1685 5 confounders confounder NNS cord-006870-f5w6fw6q 1685 6 , , , cord-006870-f5w6fw6q 1685 7 mean mean JJ cord-006870-f5w6fw6q 1685 8 R r NN cord-006870-f5w6fw6q 1685 9 time time NN cord-006870-f5w6fw6q 1685 10 was be VBD cord-006870-f5w6fw6q 1685 11 independently independently RB cord-006870-f5w6fw6q 1685 12 associated associate VBN cord-006870-f5w6fw6q 1685 13 with with IN cord-006870-f5w6fw6q 1685 14 HE HE NNP cord-006870-f5w6fw6q 1685 15 ( ( -LRB- cord-006870-f5w6fw6q 1685 16 5.3 5.3 CD cord-006870-f5w6fw6q 1685 17 ± ± NNP cord-006870-f5w6fw6q 1685 18 0.4 0.4 CD cord-006870-f5w6fw6q 1685 19 vs. vs. NN cord-006870-f5w6fw6q 1685 20 4.8 4.8 CD cord-006870-f5w6fw6q 1685 21 ± ± NNP cord-006870-f5w6fw6q 1685 22 0.2 0.2 CD cord-006870-f5w6fw6q 1685 23 mi mi NNP cord-006870-f5w6fw6q 1685 24 significantly significantly RB cord-006870-f5w6fw6q 1685 25 higher high JJR cord-006870-f5w6fw6q 1685 26 risk risk NN cord-006870-f5w6fw6q 1685 27 of of IN cord-006870-f5w6fw6q 1685 28 HE he PRP cord-006870-f5w6fw6q 1685 29 with with IN cord-006870-f5w6fw6q 1685 30 OR OR NNP cord-006870-f5w6fw6q 1685 31 2.63 2.63 CD cord-006870-f5w6fw6q 1686 1 ( ( -LRB- cord-006870-f5w6fw6q 1686 2 95 95 CD cord-006870-f5w6fw6q 1686 3 % % NN cord-006870-f5w6fw6q 1686 4 CI ci NN cord-006870-f5w6fw6q 1686 5 : : : cord-006870-f5w6fw6q 1686 6 1.49 1.49 CD cord-006870-f5w6fw6q 1686 7 , , , cord-006870-f5w6fw6q 1686 8 4.65 4.65 CD cord-006870-f5w6fw6q 1686 9 ) ) -RRB- cord-006870-f5w6fw6q 1686 10 , , , cord-006870-f5w6fw6q 1686 11 p=<0.001 p=<0.001 NNP cord-006870-f5w6fw6q 1686 12 . . . cord-006870-f5w6fw6q 1687 1 Patients patient NNS cord-006870-f5w6fw6q 1687 2 with with IN cord-006870-f5w6fw6q 1687 3 hematoma hematoma NN cord-006870-f5w6fw6q 1687 4 expansion expansion NN cord-006870-f5w6fw6q 1687 5 were be VBD cord-006870-f5w6fw6q 1687 6 more more RBR cord-006870-f5w6fw6q 1687 7 likely likely JJ cord-006870-f5w6fw6q 1687 8 to to TO cord-006870-f5w6fw6q 1687 9 have have VB cord-006870-f5w6fw6q 1687 10 poor poor JJ cord-006870-f5w6fw6q 1687 11 neurological neurological JJ cord-006870-f5w6fw6q 1687 12 outcome outcome NN cord-006870-f5w6fw6q 1687 13 ( ( -LRB- cord-006870-f5w6fw6q 1687 14 mRS mrs PRP$ cord-006870-f5w6fw6q 1687 15 4 4 CD cord-006870-f5w6fw6q 1687 16 - - SYM cord-006870-f5w6fw6q 1687 17 6 6 CD cord-006870-f5w6fw6q 1687 18 ) ) -RRB- cord-006870-f5w6fw6q 1687 19 at at IN cord-006870-f5w6fw6q 1687 20 discharge discharge NN cord-006870-f5w6fw6q 1687 21 ( ( -LRB- cord-006870-f5w6fw6q 1687 22 91 91 CD cord-006870-f5w6fw6q 1687 23 % % NN cord-006870-f5w6fw6q 1687 24 vs. vs. IN cord-006870-f5w6fw6q 1687 25 73 73 CD cord-006870-f5w6fw6q 1687 26 % % NN cord-006870-f5w6fw6q 1687 27 , , , cord-006870-f5w6fw6q 1687 28 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 1687 29 ) ) -RRB- cord-006870-f5w6fw6q 1687 30 and and CC cord-006870-f5w6fw6q 1687 31 had have VBD cord-006870-f5w6fw6q 1687 32 higher high JJR cord-006870-f5w6fw6q 1687 33 mortality mortality NN cord-006870-f5w6fw6q 1687 34 rates rate NNS cord-006870-f5w6fw6q 1687 35 ( ( -LRB- cord-006870-f5w6fw6q 1687 36 28 28 CD cord-006870-f5w6fw6q 1687 37 % % NN cord-006870-f5w6fw6q 1687 38 vs. vs. IN cord-006870-f5w6fw6q 1687 39 14 14 CD cord-006870-f5w6fw6q 1687 40 % % NN cord-006870-f5w6fw6q 1687 41 , , , cord-006870-f5w6fw6q 1687 42 p=0.005 p=0.005 NNP cord-006870-f5w6fw6q 1687 43 ) ) -RRB- cord-006870-f5w6fw6q 1687 44 . . . cord-006870-f5w6fw6q 1688 1 Overall overall RB cord-006870-f5w6fw6q 1688 2 , , , cord-006870-f5w6fw6q 1688 3 47 47 CD cord-006870-f5w6fw6q 1688 4 patients patient NNS cord-006870-f5w6fw6q 1688 5 ( ( -LRB- cord-006870-f5w6fw6q 1688 6 17 17 CD cord-006870-f5w6fw6q 1688 7 % % NN cord-006870-f5w6fw6q 1688 8 ) ) -RRB- cord-006870-f5w6fw6q 1688 9 died die VBD cord-006870-f5w6fw6q 1688 10 in in IN cord-006870-f5w6fw6q 1688 11 the the DT cord-006870-f5w6fw6q 1688 12 hospital hospital NN cord-006870-f5w6fw6q 1688 13 . . . cord-006870-f5w6fw6q 1689 1 Following follow VBG cord-006870-f5w6fw6q 1689 2 multivariable multivariable JJ cord-006870-f5w6fw6q 1689 3 analysis analysis NN cord-006870-f5w6fw6q 1689 4 , , , cord-006870-f5w6fw6q 1689 5 patients patient NNS cord-006870-f5w6fw6q 1689 6 who who WP cord-006870-f5w6fw6q 1689 7 died die VBD cord-006870-f5w6fw6q 1689 8 had have VBD cord-006870-f5w6fw6q 1689 9 significantly significantly RB cord-006870-f5w6fw6q 1689 10 lower low JJR cord-006870-f5w6fw6q 1689 11 mean mean JJ cord-006870-f5w6fw6q 1689 12 delta delta NN cord-006870-f5w6fw6q 1689 13 ( ( -LRB- cord-006870-f5w6fw6q 1690 1 0.4 0.4 CD cord-006870-f5w6fw6q 1690 2 ± ± CD cord-006870-f5w6fw6q 1690 3 0.2 0.2 CD cord-006870-f5w6fw6q 1690 4 vs. vs. NN cord-006870-f5w6fw6q 1690 5 0.6 0.6 CD cord-006870-f5w6fw6q 1690 6 ± ± CD cord-006870-f5w6fw6q 1690 7 0.2 0.2 CD cord-006870-f5w6fw6q 1690 8 mins min NNS cord-006870-f5w6fw6q 1690 9 . . . cord-006870-f5w6fw6q 1690 10 ; ; : cord-006870-f5w6fw6q 1690 11 p=0.04 p=0.04 NN cord-006870-f5w6fw6q 1690 12 ) ) -RRB- cord-006870-f5w6fw6q 1690 13 and and CC cord-006870-f5w6fw6q 1690 14 smaller small JJR cord-006870-f5w6fw6q 1690 15 angle angle NN cord-006870-f5w6fw6q 1690 16 ( ( -LRB- cord-006870-f5w6fw6q 1691 1 69.9 69.9 CD cord-006870-f5w6fw6q 1691 2 ± ± NNP cord-006870-f5w6fw6q 1691 3 3.1 3.1 CD cord-006870-f5w6fw6q 1691 4 vs. vs. IN cord-006870-f5w6fw6q 1691 5 66.1 66.1 CD cord-006870-f5w6fw6q 1691 6 ± ± CD cord-006870-f5w6fw6q 1691 7 1.9 1.9 CD cord-006870-f5w6fw6q 1691 8 degrees degree NNS cord-006870-f5w6fw6q 1691 9 ; ; : cord-006870-f5w6fw6q 1691 10 p=0.01 p=0.01 JJ cord-006870-f5w6fw6q 1691 11 ) ) -RRB- cord-006870-f5w6fw6q 1691 12 than than IN cord-006870-f5w6fw6q 1691 13 those those DT cord-006870-f5w6fw6q 1691 14 who who WP cord-006870-f5w6fw6q 1691 15 lived live VBD cord-006870-f5w6fw6q 1691 16 . . . cord-006870-f5w6fw6q 1692 1 Hematoma hematoma NN cord-006870-f5w6fw6q 1692 2 expansion expansion NN cord-006870-f5w6fw6q 1692 3 and and CC cord-006870-f5w6fw6q 1692 4 mortality mortality NN cord-006870-f5w6fw6q 1692 5 from from IN cord-006870-f5w6fw6q 1692 6 ICH ICH NNP cord-006870-f5w6fw6q 1692 7 are be VBP cord-006870-f5w6fw6q 1692 8 independently independently RB cord-006870-f5w6fw6q 1692 9 associated associate VBN cord-006870-f5w6fw6q 1692 10 with with IN cord-006870-f5w6fw6q 1692 11 slower slow JJR cord-006870-f5w6fw6q 1692 12 clot clot NN cord-006870-f5w6fw6q 1692 13 formation formation NN cord-006870-f5w6fw6q 1692 14 on on IN cord-006870-f5w6fw6q 1692 15 TEG TEG NNP cord-006870-f5w6fw6q 1692 16 . . . cord-006870-f5w6fw6q 1693 1 Baseline Baseline NNP cord-006870-f5w6fw6q 1693 2 TEG TEG NNP cord-006870-f5w6fw6q 1693 3 identifies identify VBZ cord-006870-f5w6fw6q 1693 4 significant significant JJ cord-006870-f5w6fw6q 1693 5 coagulation coagulation NN cord-006870-f5w6fw6q 1693 6 disturbances disturbance NNS cord-006870-f5w6fw6q 1693 7 which which WDT cord-006870-f5w6fw6q 1693 8 may may MD cord-006870-f5w6fw6q 1693 9 predict predict VB cord-006870-f5w6fw6q 1693 10 poor poor JJ cord-006870-f5w6fw6q 1693 11 outcome outcome NN cord-006870-f5w6fw6q 1693 12 and and CC cord-006870-f5w6fw6q 1693 13 represent represent VB cord-006870-f5w6fw6q 1693 14 potential potential JJ cord-006870-f5w6fw6q 1693 15 targets target NNS cord-006870-f5w6fw6q 1693 16 for for IN cord-006870-f5w6fw6q 1693 17 therapeutic therapeutic JJ cord-006870-f5w6fw6q 1693 18 intervention intervention NN cord-006870-f5w6fw6q 1693 19 . . . cord-006870-f5w6fw6q 1694 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 1694 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1694 3 ( ( -LRB- cord-006870-f5w6fw6q 1694 4 ICH ICH NNP cord-006870-f5w6fw6q 1694 5 ) ) -RRB- cord-006870-f5w6fw6q 1694 6 patients patient NNS cord-006870-f5w6fw6q 1694 7 often often RB cord-006870-f5w6fw6q 1694 8 present present JJ cord-006870-f5w6fw6q 1694 9 with with IN cord-006870-f5w6fw6q 1694 10 acute acute JJ cord-006870-f5w6fw6q 1694 11 hypertension hypertension NN cord-006870-f5w6fw6q 1694 12 requiring require VBG cord-006870-f5w6fw6q 1694 13 intravenous intravenous JJ cord-006870-f5w6fw6q 1694 14 and and CC cord-006870-f5w6fw6q 1694 15 enteral enteral JJ cord-006870-f5w6fw6q 1694 16 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1694 17 medications medication NNS cord-006870-f5w6fw6q 1694 18 . . . cord-006870-f5w6fw6q 1695 1 We -PRON- PRP cord-006870-f5w6fw6q 1695 2 performed perform VBD cord-006870-f5w6fw6q 1695 3 a a DT cord-006870-f5w6fw6q 1695 4 cohort cohort NN cord-006870-f5w6fw6q 1695 5 study study NN cord-006870-f5w6fw6q 1695 6 to to TO cord-006870-f5w6fw6q 1695 7 determine determine VB cord-006870-f5w6fw6q 1695 8 clinical clinical JJ cord-006870-f5w6fw6q 1695 9 predictors predictor NNS cord-006870-f5w6fw6q 1695 10 of of IN cord-006870-f5w6fw6q 1695 11 time time NN cord-006870-f5w6fw6q 1695 12 to to IN cord-006870-f5w6fw6q 1695 13 enteral enteral JJ cord-006870-f5w6fw6q 1695 14 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1695 15 medication medication NN cord-006870-f5w6fw6q 1695 16 and and CC cord-006870-f5w6fw6q 1695 17 its -PRON- PRP$ cord-006870-f5w6fw6q 1695 18 effect effect NN cord-006870-f5w6fw6q 1695 19 on on IN cord-006870-f5w6fw6q 1695 20 ICU ICU NNP cord-006870-f5w6fw6q 1695 21 length length NN cord-006870-f5w6fw6q 1695 22 of of IN cord-006870-f5w6fw6q 1695 23 stay stay NN cord-006870-f5w6fw6q 1695 24 ( ( -LRB- cord-006870-f5w6fw6q 1695 25 ICU ICU NNP cord-006870-f5w6fw6q 1695 26 LOS LOS NNP cord-006870-f5w6fw6q 1695 27 ) ) -RRB- cord-006870-f5w6fw6q 1695 28 . . . cord-006870-f5w6fw6q 1696 1 We -PRON- PRP cord-006870-f5w6fw6q 1696 2 identified identify VBD cord-006870-f5w6fw6q 1696 3 consecutive consecutive JJ cord-006870-f5w6fw6q 1696 4 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1696 5 ICH ICH NNP cord-006870-f5w6fw6q 1696 6 patients patient NNS cord-006870-f5w6fw6q 1696 7 admitted admit VBN cord-006870-f5w6fw6q 1696 8 from from IN cord-006870-f5w6fw6q 1696 9 12/2013 12/2013 CD cord-006870-f5w6fw6q 1696 10 to to IN cord-006870-f5w6fw6q 1696 11 9/2015 9/2015 CD cord-006870-f5w6fw6q 1696 12 to to IN cord-006870-f5w6fw6q 1696 13 a a DT cord-006870-f5w6fw6q 1696 14 tertiary tertiary JJ cord-006870-f5w6fw6q 1696 15 center center NN cord-006870-f5w6fw6q 1696 16 , , , cord-006870-f5w6fw6q 1696 17 and and CC cord-006870-f5w6fw6q 1696 18 excluded exclude VBD cord-006870-f5w6fw6q 1696 19 those those DT cord-006870-f5w6fw6q 1696 20 transitioned transition VBN cord-006870-f5w6fw6q 1696 21 to to IN cord-006870-f5w6fw6q 1696 22 comfort comfort NN cord-006870-f5w6fw6q 1696 23 care care NN cord-006870-f5w6fw6q 1696 24 ( ( -LRB- cord-006870-f5w6fw6q 1696 25 CMO CMO NNP cord-006870-f5w6fw6q 1696 26 ) ) -RRB- cord-006870-f5w6fw6q 1696 27 within within IN cord-006870-f5w6fw6q 1696 28 24 24 CD cord-006870-f5w6fw6q 1696 29 hours hour NNS cord-006870-f5w6fw6q 1696 30 of of IN cord-006870-f5w6fw6q 1696 31 admission admission NN cord-006870-f5w6fw6q 1696 32 . . . cord-006870-f5w6fw6q 1697 1 We -PRON- PRP cord-006870-f5w6fw6q 1697 2 calculated calculate VBD cord-006870-f5w6fw6q 1697 3 time time NN cord-006870-f5w6fw6q 1697 4 from from IN cord-006870-f5w6fw6q 1697 5 hospital hospital NN cord-006870-f5w6fw6q 1697 6 admission admission NN cord-006870-f5w6fw6q 1697 7 to to IN cord-006870-f5w6fw6q 1697 8 first first JJ cord-006870-f5w6fw6q 1697 9 enteral enteral JJ cord-006870-f5w6fw6q 1697 10 ( ( -LRB- cord-006870-f5w6fw6q 1697 11 oral oral JJ cord-006870-f5w6fw6q 1697 12 or or CC cord-006870-f5w6fw6q 1697 13 feeding feed VBG cord-006870-f5w6fw6q 1697 14 tube tube NN cord-006870-f5w6fw6q 1697 15 ) ) -RRB- cord-006870-f5w6fw6q 1697 16 antihypertensive antihypertensive NN cord-006870-f5w6fw6q 1697 17 . . . cord-006870-f5w6fw6q 1698 1 We -PRON- PRP cord-006870-f5w6fw6q 1698 2 abstracted abstract VBD cord-006870-f5w6fw6q 1698 3 demographic demographic JJ cord-006870-f5w6fw6q 1698 4 and and CC cord-006870-f5w6fw6q 1698 5 clinical clinical JJ cord-006870-f5w6fw6q 1698 6 variables variable NNS cord-006870-f5w6fw6q 1698 7 . . . cord-006870-f5w6fw6q 1699 1 Two two CD cord-006870-f5w6fw6q 1699 2 reviewers reviewer NNS cord-006870-f5w6fw6q 1699 3 examined examine VBD cord-006870-f5w6fw6q 1699 4 medical medical JJ cord-006870-f5w6fw6q 1699 5 records record NNS cord-006870-f5w6fw6q 1699 6 and and CC cord-006870-f5w6fw6q 1699 7 classified classify VBD cord-006870-f5w6fw6q 1699 8 ICH ICH NNP cord-006870-f5w6fw6q 1699 9 location location NN cord-006870-f5w6fw6q 1699 10 and and CC cord-006870-f5w6fw6q 1699 11 etiology etiology NN cord-006870-f5w6fw6q 1699 12 . . . cord-006870-f5w6fw6q 1700 1 We -PRON- PRP cord-006870-f5w6fw6q 1700 2 determined determine VBD cord-006870-f5w6fw6q 1700 3 univariate univariate JJ cord-006870-f5w6fw6q 1700 4 and and CC cord-006870-f5w6fw6q 1700 5 adjusted adjusted JJ cord-006870-f5w6fw6q 1700 6 associations association NNS cord-006870-f5w6fw6q 1700 7 of of IN cord-006870-f5w6fw6q 1700 8 clinical clinical JJ cord-006870-f5w6fw6q 1700 9 variables variable NNS cord-006870-f5w6fw6q 1700 10 to to IN cord-006870-f5w6fw6q 1700 11 time time NN cord-006870-f5w6fw6q 1700 12 to to IN cord-006870-f5w6fw6q 1700 13 enteral enteral JJ cord-006870-f5w6fw6q 1700 14 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1700 15 medication medication NN cord-006870-f5w6fw6q 1700 16 and and CC cord-006870-f5w6fw6q 1700 17 performed perform VBN cord-006870-f5w6fw6q 1700 18 regression regression NN cord-006870-f5w6fw6q 1700 19 analysis analysis NN cord-006870-f5w6fw6q 1700 20 to to TO cord-006870-f5w6fw6q 1700 21 determine determine VB cord-006870-f5w6fw6q 1700 22 effect effect NN cord-006870-f5w6fw6q 1700 23 on on IN cord-006870-f5w6fw6q 1700 24 ICU ICU NNP cord-006870-f5w6fw6q 1700 25 LOS LOS NNP cord-006870-f5w6fw6q 1700 26 . . . cord-006870-f5w6fw6q 1701 1 We -PRON- PRP cord-006870-f5w6fw6q 1701 2 identified identify VBD cord-006870-f5w6fw6q 1701 3 495 495 CD cord-006870-f5w6fw6q 1701 4 patients patient NNS cord-006870-f5w6fw6q 1701 5 and and CC cord-006870-f5w6fw6q 1701 6 excluded exclude VBD cord-006870-f5w6fw6q 1701 7 50 50 CD cord-006870-f5w6fw6q 1701 8 for for IN cord-006870-f5w6fw6q 1701 9 early early JJ cord-006870-f5w6fw6q 1701 10 transition transition NN cord-006870-f5w6fw6q 1701 11 to to IN cord-006870-f5w6fw6q 1701 12 CMO CMO NNP cord-006870-f5w6fw6q 1701 13 . . . cord-006870-f5w6fw6q 1702 1 Endotracheal endotracheal JJ cord-006870-f5w6fw6q 1702 2 intubation intubation NN cord-006870-f5w6fw6q 1702 3 ( ( -LRB- cord-006870-f5w6fw6q 1702 4 p=0.03 p=0.03 NN cord-006870-f5w6fw6q 1702 5 ) ) -RRB- cord-006870-f5w6fw6q 1702 6 , , , cord-006870-f5w6fw6q 1702 7 higher high JJR cord-006870-f5w6fw6q 1702 8 ICH ICH NNP cord-006870-f5w6fw6q 1702 9 score score NN cord-006870-f5w6fw6q 1702 10 ( ( -LRB- cord-006870-f5w6fw6q 1702 11 p<0.001 p<0.001 NNS cord-006870-f5w6fw6q 1702 12 ) ) -RRB- cord-006870-f5w6fw6q 1702 13 , , , cord-006870-f5w6fw6q 1702 14 no no DT cord-006870-f5w6fw6q 1702 15 outpatient outpatient NN cord-006870-f5w6fw6q 1702 16 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1702 17 use use NN cord-006870-f5w6fw6q 1702 18 ( ( -LRB- cord-006870-f5w6fw6q 1702 19 p=0.001 p=0.001 NNP cord-006870-f5w6fw6q 1702 20 ) ) -RRB- cord-006870-f5w6fw6q 1702 21 , , , cord-006870-f5w6fw6q 1702 22 and and CC cord-006870-f5w6fw6q 1702 23 non non JJ cord-006870-f5w6fw6q 1702 24 - - JJ cord-006870-f5w6fw6q 1702 25 lobar lobar JJ cord-006870-f5w6fw6q 1702 26 ICH ICH NNP cord-006870-f5w6fw6q 1702 27 location location NN cord-006870-f5w6fw6q 1702 28 ( ( -LRB- cord-006870-f5w6fw6q 1702 29 p=0.005 p=0.005 NNP cord-006870-f5w6fw6q 1702 30 ) ) -RRB- cord-006870-f5w6fw6q 1702 31 predicted predict VBN cord-006870-f5w6fw6q 1702 32 longer long JJR cord-006870-f5w6fw6q 1702 33 time time NN cord-006870-f5w6fw6q 1702 34 to to TO cord-006870-f5w6fw6q 1702 35 starting start VBG cord-006870-f5w6fw6q 1702 36 enteral enteral JJ cord-006870-f5w6fw6q 1702 37 antihypertensive antihypertensive RB cord-006870-f5w6fw6q 1702 38 in in IN cord-006870-f5w6fw6q 1702 39 adjusted adjust VBN cord-006870-f5w6fw6q 1702 40 analysis analysis NN cord-006870-f5w6fw6q 1702 41 . . . cord-006870-f5w6fw6q 1703 1 Presenting present VBG cord-006870-f5w6fw6q 1703 2 systolic systolic JJ cord-006870-f5w6fw6q 1703 3 or or CC cord-006870-f5w6fw6q 1703 4 diastolic diastolic JJ cord-006870-f5w6fw6q 1703 5 BP BP NNP cord-006870-f5w6fw6q 1703 6 , , , cord-006870-f5w6fw6q 1703 7 time time NN cord-006870-f5w6fw6q 1703 8 of of IN cord-006870-f5w6fw6q 1703 9 ICU ICU NNP cord-006870-f5w6fw6q 1703 10 admission admission NN cord-006870-f5w6fw6q 1703 11 ( ( -LRB- cord-006870-f5w6fw6q 1703 12 day day NN cord-006870-f5w6fw6q 1703 13 vs. vs. IN cord-006870-f5w6fw6q 1703 14 night night NN cord-006870-f5w6fw6q 1703 15 ) ) -RRB- cord-006870-f5w6fw6q 1703 16 , , , cord-006870-f5w6fw6q 1703 17 sex sex NN cord-006870-f5w6fw6q 1703 18 , , , cord-006870-f5w6fw6q 1703 19 and and CC cord-006870-f5w6fw6q 1703 20 race race NN cord-006870-f5w6fw6q 1703 21 were be VBD cord-006870-f5w6fw6q 1703 22 not not RB cord-006870-f5w6fw6q 1703 23 significant significant JJ cord-006870-f5w6fw6q 1703 24 predictors predictor NNS cord-006870-f5w6fw6q 1703 25 of of IN cord-006870-f5w6fw6q 1703 26 time time NN cord-006870-f5w6fw6q 1703 27 to to IN cord-006870-f5w6fw6q 1703 28 enteral enteral JJ cord-006870-f5w6fw6q 1703 29 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1703 30 . . . cord-006870-f5w6fw6q 1704 1 Time time NN cord-006870-f5w6fw6q 1704 2 to to TO cord-006870-f5w6fw6q 1704 3 enteral enteral JJ cord-006870-f5w6fw6q 1704 4 anti anti JJ cord-006870-f5w6fw6q 1704 5 - - JJ cord-006870-f5w6fw6q 1704 6 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1704 7 is be VBZ cord-006870-f5w6fw6q 1704 8 the the DT cord-006870-f5w6fw6q 1704 9 strongest strong JJS cord-006870-f5w6fw6q 1704 10 predictor predictor NN cord-006870-f5w6fw6q 1704 11 of of IN cord-006870-f5w6fw6q 1704 12 ICU ICU NNP cord-006870-f5w6fw6q 1704 13 LOS LOS NNP cord-006870-f5w6fw6q 1704 14 ( ( -LRB- cord-006870-f5w6fw6q 1704 15 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 1704 16 ) ) -RRB- cord-006870-f5w6fw6q 1704 17 after after IN cord-006870-f5w6fw6q 1704 18 adjustment adjustment NN cord-006870-f5w6fw6q 1704 19 for for IN cord-006870-f5w6fw6q 1704 20 age age NN cord-006870-f5w6fw6q 1704 21 , , , cord-006870-f5w6fw6q 1704 22 GCS GCS NNP cord-006870-f5w6fw6q 1704 23 , , , cord-006870-f5w6fw6q 1704 24 ICH ICH NNP cord-006870-f5w6fw6q 1704 25 score score NN cord-006870-f5w6fw6q 1704 26 , , , cord-006870-f5w6fw6q 1704 27 sex sex NN cord-006870-f5w6fw6q 1704 28 , , , cord-006870-f5w6fw6q 1704 29 race race NN cord-006870-f5w6fw6q 1704 30 , , , cord-006870-f5w6fw6q 1704 31 and and CC cord-006870-f5w6fw6q 1704 32 duration duration NN cord-006870-f5w6fw6q 1704 33 of of IN cord-006870-f5w6fw6q 1704 34 IV IV NNP cord-006870-f5w6fw6q 1704 35 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1704 36 infusion infusion NN cord-006870-f5w6fw6q 1704 37 . . . cord-006870-f5w6fw6q 1705 1 Patients patient NNS cord-006870-f5w6fw6q 1705 2 with with IN cord-006870-f5w6fw6q 1705 3 higher high JJR cord-006870-f5w6fw6q 1705 4 ICH ICH NNP cord-006870-f5w6fw6q 1705 5 scores score NNS cord-006870-f5w6fw6q 1705 6 , , , cord-006870-f5w6fw6q 1705 7 intubation intubation NN cord-006870-f5w6fw6q 1705 8 , , , cord-006870-f5w6fw6q 1705 9 no no DT cord-006870-f5w6fw6q 1705 10 prior prior JJ cord-006870-f5w6fw6q 1705 11 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1705 12 use use NN cord-006870-f5w6fw6q 1705 13 , , , cord-006870-f5w6fw6q 1705 14 and and CC cord-006870-f5w6fw6q 1705 15 non non JJ cord-006870-f5w6fw6q 1705 16 - - JJ cord-006870-f5w6fw6q 1705 17 lobar lobar JJ cord-006870-f5w6fw6q 1705 18 ICH ICH NNP cord-006870-f5w6fw6q 1705 19 are be VBP cord-006870-f5w6fw6q 1705 20 at at IN cord-006870-f5w6fw6q 1705 21 risk risk NN cord-006870-f5w6fw6q 1705 22 for for IN cord-006870-f5w6fw6q 1705 23 increased increase VBN cord-006870-f5w6fw6q 1705 24 time time NN cord-006870-f5w6fw6q 1705 25 to to IN cord-006870-f5w6fw6q 1705 26 enteral enteral JJ cord-006870-f5w6fw6q 1705 27 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1705 28 administration administration NN cord-006870-f5w6fw6q 1705 29 . . . cord-006870-f5w6fw6q 1706 1 Timely timely RB cord-006870-f5w6fw6q 1706 2 enteral enteral JJ cord-006870-f5w6fw6q 1706 3 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 1706 4 administration administration NN cord-006870-f5w6fw6q 1706 5 is be VBZ cord-006870-f5w6fw6q 1706 6 an an DT cord-006870-f5w6fw6q 1706 7 important important JJ cord-006870-f5w6fw6q 1706 8 and and CC cord-006870-f5w6fw6q 1706 9 potentially potentially RB cord-006870-f5w6fw6q 1706 10 modifiable modifiable JJ cord-006870-f5w6fw6q 1706 11 predictor predictor NN cord-006870-f5w6fw6q 1706 12 of of IN cord-006870-f5w6fw6q 1706 13 ICU ICU NNP cord-006870-f5w6fw6q 1706 14 LOS LOS NNP cord-006870-f5w6fw6q 1706 15 in in IN cord-006870-f5w6fw6q 1706 16 acute acute JJ cord-006870-f5w6fw6q 1706 17 ICH ICH NNP cord-006870-f5w6fw6q 1706 18 . . . cord-006870-f5w6fw6q 1707 1 Overall overall JJ cord-006870-f5w6fw6q 1707 2 mortality mortality NN cord-006870-f5w6fw6q 1707 3 from from IN cord-006870-f5w6fw6q 1707 4 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1707 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1707 6 ( ( -LRB- cord-006870-f5w6fw6q 1707 7 ICH ICH NNP cord-006870-f5w6fw6q 1707 8 ) ) -RRB- cord-006870-f5w6fw6q 1707 9 represents represent VBZ cord-006870-f5w6fw6q 1707 10 a a DT cord-006870-f5w6fw6q 1707 11 combination combination NN cord-006870-f5w6fw6q 1707 12 mortality mortality NN cord-006870-f5w6fw6q 1707 13 from from IN cord-006870-f5w6fw6q 1707 14 a a DT cord-006870-f5w6fw6q 1707 15 potentially potentially RB cord-006870-f5w6fw6q 1707 16 fatal fatal JJ cord-006870-f5w6fw6q 1707 17 disease disease NN cord-006870-f5w6fw6q 1707 18 as as RB cord-006870-f5w6fw6q 1707 19 well well RB cord-006870-f5w6fw6q 1707 20 as as IN cord-006870-f5w6fw6q 1707 21 practice practice NN cord-006870-f5w6fw6q 1707 22 variation variation NN cord-006870-f5w6fw6q 1707 23 around around IN cord-006870-f5w6fw6q 1707 24 treatment treatment NN cord-006870-f5w6fw6q 1707 25 withdrawal withdrawal NN cord-006870-f5w6fw6q 1707 26 of of IN cord-006870-f5w6fw6q 1707 27 care care NN cord-006870-f5w6fw6q 1707 28 . . . cord-006870-f5w6fw6q 1708 1 Early early JJ cord-006870-f5w6fw6q 1708 2 Do do VB cord-006870-f5w6fw6q 1708 3 - - HYPH cord-006870-f5w6fw6q 1708 4 Not not RB cord-006870-f5w6fw6q 1708 5 - - HYPH cord-006870-f5w6fw6q 1708 6 Resuscitate resuscitate VB cord-006870-f5w6fw6q 1708 7 ( ( -LRB- cord-006870-f5w6fw6q 1708 8 DNR DNR NNP cord-006870-f5w6fw6q 1708 9 ) ) -RRB- cord-006870-f5w6fw6q 1708 10 rates rate NNS cord-006870-f5w6fw6q 1708 11 are be VBP cord-006870-f5w6fw6q 1708 12 independently independently RB cord-006870-f5w6fw6q 1708 13 associated associate VBN cord-006870-f5w6fw6q 1708 14 with with IN cord-006870-f5w6fw6q 1708 15 in in IN cord-006870-f5w6fw6q 1708 16 - - HYPH cord-006870-f5w6fw6q 1708 17 hospital hospital NN cord-006870-f5w6fw6q 1708 18 mortality mortality NN cord-006870-f5w6fw6q 1708 19 and and CC cord-006870-f5w6fw6q 1708 20 may may MD cord-006870-f5w6fw6q 1708 21 serve serve VB cord-006870-f5w6fw6q 1708 22 as as IN cord-006870-f5w6fw6q 1708 23 a a DT cord-006870-f5w6fw6q 1708 24 proxy proxy NN cord-006870-f5w6fw6q 1708 25 for for IN cord-006870-f5w6fw6q 1708 26 withholding withhold VBG cord-006870-f5w6fw6q 1708 27 aggressive aggressive JJ cord-006870-f5w6fw6q 1708 28 care care NN cord-006870-f5w6fw6q 1708 29 . . . cord-006870-f5w6fw6q 1709 1 The the DT cord-006870-f5w6fw6q 1709 2 2007 2007 CD cord-006870-f5w6fw6q 1709 3 American American NNP cord-006870-f5w6fw6q 1709 4 Heart Heart NNP cord-006870-f5w6fw6q 1709 5 Association Association NNP cord-006870-f5w6fw6q 1709 6 ( ( -LRB- cord-006870-f5w6fw6q 1709 7 AHA AHA NNP cord-006870-f5w6fw6q 1709 8 ) ) -RRB- cord-006870-f5w6fw6q 1710 1 Guidelines guideline NNS cord-006870-f5w6fw6q 1710 2 recommended recommend VBD cord-006870-f5w6fw6q 1710 3 that that IN cord-006870-f5w6fw6q 1710 4 DNR DNR NNP cord-006870-f5w6fw6q 1710 5 orders order NNS cord-006870-f5w6fw6q 1710 6 should should MD cord-006870-f5w6fw6q 1710 7 not not RB cord-006870-f5w6fw6q 1710 8 be be VB cord-006870-f5w6fw6q 1710 9 applied apply VBN cord-006870-f5w6fw6q 1710 10 before before IN cord-006870-f5w6fw6q 1710 11 24 24 CD cord-006870-f5w6fw6q 1710 12 hours hour NNS cord-006870-f5w6fw6q 1710 13 out out IN cord-006870-f5w6fw6q 1710 14 of of IN cord-006870-f5w6fw6q 1710 15 a a DT cord-006870-f5w6fw6q 1710 16 concern concern NN cord-006870-f5w6fw6q 1710 17 that that IN cord-006870-f5w6fw6q 1710 18 less less RBR cord-006870-f5w6fw6q 1710 19 aggressive aggressive JJ cord-006870-f5w6fw6q 1710 20 care care NN cord-006870-f5w6fw6q 1710 21 would would MD cord-006870-f5w6fw6q 1710 22 lead lead VB cord-006870-f5w6fw6q 1710 23 to to IN cord-006870-f5w6fw6q 1710 24 a a DT cord-006870-f5w6fw6q 1710 25 self self NN cord-006870-f5w6fw6q 1710 26 - - HYPH cord-006870-f5w6fw6q 1710 27 fulfilling fulfil VBG cord-006870-f5w6fw6q 1710 28 prophecy prophecy NN cord-006870-f5w6fw6q 1710 29 and and CC cord-006870-f5w6fw6q 1710 30 excess excess JJ cord-006870-f5w6fw6q 1710 31 mortality mortality NN cord-006870-f5w6fw6q 1710 32 . . . cord-006870-f5w6fw6q 1711 1 We -PRON- PRP cord-006870-f5w6fw6q 1711 2 performed perform VBD cord-006870-f5w6fw6q 1711 3 a a DT cord-006870-f5w6fw6q 1711 4 retrospective retrospective JJ cord-006870-f5w6fw6q 1711 5 analysis analysis NN cord-006870-f5w6fw6q 1711 6 of of IN cord-006870-f5w6fw6q 1711 7 temporal temporal JJ cord-006870-f5w6fw6q 1711 8 trends trend NNS cord-006870-f5w6fw6q 1711 9 among among IN cord-006870-f5w6fw6q 1711 10 primary primary JJ cord-006870-f5w6fw6q 1711 11 ICH ICH NNP cord-006870-f5w6fw6q 1711 12 patients patient NNS cord-006870-f5w6fw6q 1711 13 presenting present VBG cord-006870-f5w6fw6q 1711 14 to to IN cord-006870-f5w6fw6q 1711 15 all all DT cord-006870-f5w6fw6q 1711 16 nonfederal nonfederal JJ cord-006870-f5w6fw6q 1711 17 emergency emergency NN cord-006870-f5w6fw6q 1711 18 departments department NNS cord-006870-f5w6fw6q 1711 19 in in IN cord-006870-f5w6fw6q 1711 20 California California NNP cord-006870-f5w6fw6q 1711 21 from from IN cord-006870-f5w6fw6q 1711 22 1999 1999 CD cord-006870-f5w6fw6q 1711 23 to to IN cord-006870-f5w6fw6q 1711 24 2014 2014 CD cord-006870-f5w6fw6q 1711 25 using use VBG cord-006870-f5w6fw6q 1711 26 data datum NNS cord-006870-f5w6fw6q 1711 27 from from IN cord-006870-f5w6fw6q 1711 28 the the DT cord-006870-f5w6fw6q 1711 29 Office Office NNP cord-006870-f5w6fw6q 1711 30 of of IN cord-006870-f5w6fw6q 1711 31 Statewide Statewide NNP cord-006870-f5w6fw6q 1711 32 Health Health NNP cord-006870-f5w6fw6q 1711 33 Planning Planning NNP cord-006870-f5w6fw6q 1711 34 and and CC cord-006870-f5w6fw6q 1711 35 Development Development NNP cord-006870-f5w6fw6q 1711 36 ( ( -LRB- cord-006870-f5w6fw6q 1711 37 OSHPD OSHPD NNP cord-006870-f5w6fw6q 1711 38 ) ) -RRB- cord-006870-f5w6fw6q 1711 39 . . . cord-006870-f5w6fw6q 1712 1 Demographic demographic JJ cord-006870-f5w6fw6q 1712 2 information information NN cord-006870-f5w6fw6q 1712 3 , , , cord-006870-f5w6fw6q 1712 4 clinical clinical JJ cord-006870-f5w6fw6q 1712 5 covariates covariate NNS cord-006870-f5w6fw6q 1712 6 ( ( -LRB- cord-006870-f5w6fw6q 1712 7 such such JJ cord-006870-f5w6fw6q 1712 8 as as IN cord-006870-f5w6fw6q 1712 9 mechanical mechanical JJ cord-006870-f5w6fw6q 1712 10 ventilation ventilation NN cord-006870-f5w6fw6q 1712 11 , , , cord-006870-f5w6fw6q 1712 12 craniotomy craniotomy NN cord-006870-f5w6fw6q 1712 13 ) ) -RRB- cord-006870-f5w6fw6q 1712 14 , , , cord-006870-f5w6fw6q 1712 15 and and CC cord-006870-f5w6fw6q 1712 16 early early JJ cord-006870-f5w6fw6q 1712 17 DNR DNR NNP cord-006870-f5w6fw6q 1712 18 status status NN cord-006870-f5w6fw6q 1712 19 within within IN cord-006870-f5w6fw6q 1712 20 24 24 CD cord-006870-f5w6fw6q 1712 21 hours hour NNS cord-006870-f5w6fw6q 1712 22 were be VBD cord-006870-f5w6fw6q 1712 23 collected collect VBN cord-006870-f5w6fw6q 1712 24 and and CC cord-006870-f5w6fw6q 1712 25 analyzed analyze VBN cord-006870-f5w6fw6q 1712 26 using use VBG cord-006870-f5w6fw6q 1712 27 segmented segmented JJ cord-006870-f5w6fw6q 1712 28 regression regression NN cord-006870-f5w6fw6q 1712 29 to to TO cord-006870-f5w6fw6q 1712 30 evaluate evaluate VB cord-006870-f5w6fw6q 1712 31 for for IN cord-006870-f5w6fw6q 1712 32 differences difference NNS cord-006870-f5w6fw6q 1712 33 in in IN cord-006870-f5w6fw6q 1712 34 linear linear JJ cord-006870-f5w6fw6q 1712 35 trends trend NNS cord-006870-f5w6fw6q 1712 36 from from IN cord-006870-f5w6fw6q 1712 37 1999 1999 CD cord-006870-f5w6fw6q 1712 38 - - SYM cord-006870-f5w6fw6q 1712 39 2006 2006 CD cord-006870-f5w6fw6q 1712 40 compared compare VBN cord-006870-f5w6fw6q 1712 41 with with IN cord-006870-f5w6fw6q 1712 42 2007 2007 CD cord-006870-f5w6fw6q 1712 43 - - SYM cord-006870-f5w6fw6q 1712 44 2014 2014 CD cord-006870-f5w6fw6q 1712 45 . . . cord-006870-f5w6fw6q 1713 1 Over over IN cord-006870-f5w6fw6q 1713 2 a a DT cord-006870-f5w6fw6q 1713 3 _SP cord-006870-f5w6fw6q 1713 4 Use Use NNP cord-006870-f5w6fw6q 1713 5 of of IN cord-006870-f5w6fw6q 1713 6 early early JJ cord-006870-f5w6fw6q 1713 7 DNR DNR NNP cord-006870-f5w6fw6q 1713 8 orders order NNS cord-006870-f5w6fw6q 1713 9 for for IN cord-006870-f5w6fw6q 1713 10 ICH ICH NNP cord-006870-f5w6fw6q 1713 11 patients patient NNS cord-006870-f5w6fw6q 1713 12 has have VBZ cord-006870-f5w6fw6q 1713 13 steadily steadily RB cord-006870-f5w6fw6q 1713 14 decreased decrease VBN cord-006870-f5w6fw6q 1713 15 over over IN cord-006870-f5w6fw6q 1713 16 the the DT cord-006870-f5w6fw6q 1713 17 last last JJ cord-006870-f5w6fw6q 1713 18 15 15 CD cord-006870-f5w6fw6q 1713 19 years year NNS cord-006870-f5w6fw6q 1713 20 , , , cord-006870-f5w6fw6q 1713 21 even even RB cord-006870-f5w6fw6q 1713 22 after after IN cord-006870-f5w6fw6q 1713 23 adjusting adjust VBG cord-006870-f5w6fw6q 1713 24 for for IN cord-006870-f5w6fw6q 1713 25 age age NN cord-006870-f5w6fw6q 1713 26 and and CC cord-006870-f5w6fw6q 1713 27 disease disease NN cord-006870-f5w6fw6q 1713 28 severity severity NN cord-006870-f5w6fw6q 1713 29 . . . cord-006870-f5w6fw6q 1714 1 The the DT cord-006870-f5w6fw6q 1714 2 pace pace NN cord-006870-f5w6fw6q 1714 3 of of IN cord-006870-f5w6fw6q 1714 4 this this DT cord-006870-f5w6fw6q 1714 5 downward downward JJ cord-006870-f5w6fw6q 1714 6 trend trend NN cord-006870-f5w6fw6q 1714 7 did do VBD cord-006870-f5w6fw6q 1714 8 not not RB cord-006870-f5w6fw6q 1714 9 significantly significantly RB cord-006870-f5w6fw6q 1714 10 change change VB cord-006870-f5w6fw6q 1714 11 around around IN cord-006870-f5w6fw6q 1714 12 the the DT cord-006870-f5w6fw6q 1714 13 time time NN cord-006870-f5w6fw6q 1714 14 when when WRB cord-006870-f5w6fw6q 1714 15 recommendations recommendation NNS cord-006870-f5w6fw6q 1714 16 on on IN cord-006870-f5w6fw6q 1714 17 early early JJ cord-006870-f5w6fw6q 1714 18 DNR DNR NNP cord-006870-f5w6fw6q 1714 19 use use NN cord-006870-f5w6fw6q 1714 20 for for IN cord-006870-f5w6fw6q 1714 21 ICH ICH NNP cord-006870-f5w6fw6q 1714 22 in in IN cord-006870-f5w6fw6q 1714 23 AHA AHA NNP cord-006870-f5w6fw6q 1714 24 guidelines guideline NNS cord-006870-f5w6fw6q 1714 25 were be VBD cord-006870-f5w6fw6q 1714 26 revised revise VBN cord-006870-f5w6fw6q 1714 27 in in IN cord-006870-f5w6fw6q 1714 28 2007 2007 CD cord-006870-f5w6fw6q 1714 29 . . . cord-006870-f5w6fw6q 1715 1 Spontaneous spontaneous JJ cord-006870-f5w6fw6q 1715 2 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1715 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1715 4 ( ( -LRB- cord-006870-f5w6fw6q 1715 5 ICH ICH NNP cord-006870-f5w6fw6q 1715 6 ) ) -RRB- cord-006870-f5w6fw6q 1715 7 is be VBZ cord-006870-f5w6fw6q 1715 8 a a DT cord-006870-f5w6fw6q 1715 9 common common JJ cord-006870-f5w6fw6q 1715 10 form form NN cord-006870-f5w6fw6q 1715 11 of of IN cord-006870-f5w6fw6q 1715 12 stroke stroke NN cord-006870-f5w6fw6q 1715 13 that that WDT cord-006870-f5w6fw6q 1715 14 often often RB cord-006870-f5w6fw6q 1715 15 results result VBZ cord-006870-f5w6fw6q 1715 16 in in IN cord-006870-f5w6fw6q 1715 17 severe severe JJ cord-006870-f5w6fw6q 1715 18 morbidity morbidity NN cord-006870-f5w6fw6q 1715 19 or or CC cord-006870-f5w6fw6q 1715 20 death death NN cord-006870-f5w6fw6q 1715 21 . . . cord-006870-f5w6fw6q 1716 1 For for IN cord-006870-f5w6fw6q 1716 2 most most JJS cord-006870-f5w6fw6q 1716 3 ICH ICH NNP cord-006870-f5w6fw6q 1716 4 , , , cord-006870-f5w6fw6q 1716 5 there there EX cord-006870-f5w6fw6q 1716 6 are be VBP cord-006870-f5w6fw6q 1716 7 no no DT cord-006870-f5w6fw6q 1716 8 proven prove VBN cord-006870-f5w6fw6q 1716 9 therapies therapy NNS cord-006870-f5w6fw6q 1716 10 for for IN cord-006870-f5w6fw6q 1716 11 acute acute JJ cord-006870-f5w6fw6q 1716 12 management management NN cord-006870-f5w6fw6q 1716 13 . . . cord-006870-f5w6fw6q 1717 1 Evidence evidence NN cord-006870-f5w6fw6q 1717 2 suggests suggest VBZ cord-006870-f5w6fw6q 1717 3 minimally minimally RB cord-006870-f5w6fw6q 1717 4 invasive invasive JJ cord-006870-f5w6fw6q 1717 5 surgical surgical JJ cord-006870-f5w6fw6q 1717 6 evacuation evacuation NN cord-006870-f5w6fw6q 1717 7 of of IN cord-006870-f5w6fw6q 1717 8 ICH ICH NNP cord-006870-f5w6fw6q 1717 9 may may MD cord-006870-f5w6fw6q 1717 10 result result VB cord-006870-f5w6fw6q 1717 11 in in IN cord-006870-f5w6fw6q 1717 12 improved improved JJ cord-006870-f5w6fw6q 1717 13 patient patient JJ cord-006870-f5w6fw6q 1717 14 outcomes outcome NNS cord-006870-f5w6fw6q 1717 15 . . . cord-006870-f5w6fw6q 1718 1 The the DT cord-006870-f5w6fw6q 1718 2 ENRICH enrich JJ cord-006870-f5w6fw6q 1718 3 clinical clinical JJ cord-006870-f5w6fw6q 1718 4 trial trial NN cord-006870-f5w6fw6q 1718 5 is be VBZ cord-006870-f5w6fw6q 1718 6 designed design VBN cord-006870-f5w6fw6q 1718 7 to to TO cord-006870-f5w6fw6q 1718 8 determine determine VB cord-006870-f5w6fw6q 1718 9 the the DT cord-006870-f5w6fw6q 1718 10 efficacy efficacy NN cord-006870-f5w6fw6q 1718 11 and and CC cord-006870-f5w6fw6q 1718 12 economic economic JJ cord-006870-f5w6fw6q 1718 13 impact impact NN cord-006870-f5w6fw6q 1718 14 of of IN cord-006870-f5w6fw6q 1718 15 early early JJ cord-006870-f5w6fw6q 1718 16 ICH ICH NNP cord-006870-f5w6fw6q 1718 17 evacuation evacuation NN cord-006870-f5w6fw6q 1718 18 using use VBG cord-006870-f5w6fw6q 1718 19 minimally minimally RB cord-006870-f5w6fw6q 1718 20 invasive invasive JJ cord-006870-f5w6fw6q 1718 21 , , , cord-006870-f5w6fw6q 1718 22 transulcal transulcal JJ cord-006870-f5w6fw6q 1718 23 , , , cord-006870-f5w6fw6q 1718 24 parafascicular parafascicular JJ cord-006870-f5w6fw6q 1718 25 surgery surgery NN cord-006870-f5w6fw6q 1718 26 ( ( -LRB- cord-006870-f5w6fw6q 1718 27 MIPS MIPS NNP cord-006870-f5w6fw6q 1718 28 ) ) -RRB- cord-006870-f5w6fw6q 1718 29 compared compare VBN cord-006870-f5w6fw6q 1718 30 to to IN cord-006870-f5w6fw6q 1718 31 standard standard JJ cord-006870-f5w6fw6q 1718 32 guideline guideline NN cord-006870-f5w6fw6q 1718 33 - - HYPH cord-006870-f5w6fw6q 1718 34 based base VBN cord-006870-f5w6fw6q 1718 35 management management NN cord-006870-f5w6fw6q 1718 36 . . . cord-006870-f5w6fw6q 1719 1 In in IN cord-006870-f5w6fw6q 1719 2 this this DT cord-006870-f5w6fw6q 1719 3 abstract abstract NN cord-006870-f5w6fw6q 1719 4 we -PRON- PRP cord-006870-f5w6fw6q 1719 5 present present VBP cord-006870-f5w6fw6q 1719 6 the the DT cord-006870-f5w6fw6q 1719 7 trial trial NN cord-006870-f5w6fw6q 1719 8 design design NN cord-006870-f5w6fw6q 1719 9 and and CC cord-006870-f5w6fw6q 1719 10 rationale rationale NN cord-006870-f5w6fw6q 1719 11 at at IN cord-006870-f5w6fw6q 1719 12 the the DT cord-006870-f5w6fw6q 1719 13 foundation foundation NN cord-006870-f5w6fw6q 1719 14 of of IN cord-006870-f5w6fw6q 1719 15 the the DT cord-006870-f5w6fw6q 1719 16 ENRICH enrich VB cord-006870-f5w6fw6q 1719 17 clinical clinical JJ cord-006870-f5w6fw6q 1719 18 trial trial NN cord-006870-f5w6fw6q 1719 19 . . . cord-006870-f5w6fw6q 1720 1 ENRICH enrich VB cord-006870-f5w6fw6q 1720 2 is be VBZ cord-006870-f5w6fw6q 1720 3 an an DT cord-006870-f5w6fw6q 1720 4 adaptive adaptive JJ cord-006870-f5w6fw6q 1720 5 , , , cord-006870-f5w6fw6q 1720 6 prospective prospective JJ cord-006870-f5w6fw6q 1720 7 , , , cord-006870-f5w6fw6q 1720 8 multi multi JJ cord-006870-f5w6fw6q 1720 9 - - JJ cord-006870-f5w6fw6q 1720 10 center center JJ cord-006870-f5w6fw6q 1720 11 clinical clinical JJ cord-006870-f5w6fw6q 1720 12 trial trial NN cord-006870-f5w6fw6q 1720 13 designed design VBN cord-006870-f5w6fw6q 1720 14 to to TO cord-006870-f5w6fw6q 1720 15 enroll enroll VB cord-006870-f5w6fw6q 1720 16 up up IN cord-006870-f5w6fw6q 1720 17 to to TO cord-006870-f5w6fw6q 1720 18 300 300 CD cord-006870-f5w6fw6q 1720 19 patients patient NNS cord-006870-f5w6fw6q 1720 20 with with IN cord-006870-f5w6fw6q 1720 21 acute acute JJ cord-006870-f5w6fw6q 1720 22 ICH ICH NNP cord-006870-f5w6fw6q 1720 23 . . . cord-006870-f5w6fw6q 1721 1 Patients patient NNS cord-006870-f5w6fw6q 1721 2 are be VBP cord-006870-f5w6fw6q 1721 3 block block NN cord-006870-f5w6fw6q 1721 4 - - HYPH cord-006870-f5w6fw6q 1721 5 randomized randomize VBN cord-006870-f5w6fw6q 1721 6 based base VBN cord-006870-f5w6fw6q 1721 7 on on IN cord-006870-f5w6fw6q 1721 8 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1721 9 location location NN cord-006870-f5w6fw6q 1721 10 ( ( -LRB- cord-006870-f5w6fw6q 1721 11 lobar lobar NNP cord-006870-f5w6fw6q 1721 12 vs vs IN cord-006870-f5w6fw6q 1721 13 basal basal NN cord-006870-f5w6fw6q 1721 14 ganglia ganglion NNS cord-006870-f5w6fw6q 1721 15 ) ) -RRB- cord-006870-f5w6fw6q 1721 16 1:1 1:1 CD cord-006870-f5w6fw6q 1721 17 to to IN cord-006870-f5w6fw6q 1721 18 MIPS MIPS NNP cord-006870-f5w6fw6q 1721 19 or or CC cord-006870-f5w6fw6q 1721 20 standard standard JJ cord-006870-f5w6fw6q 1721 21 management management NN cord-006870-f5w6fw6q 1721 22 . . . cord-006870-f5w6fw6q 1722 1 Included include VBN cord-006870-f5w6fw6q 1722 2 patients patient NNS cord-006870-f5w6fw6q 1722 3 are be VBP cord-006870-f5w6fw6q 1722 4 18 18 CD cord-006870-f5w6fw6q 1722 5 -80 -80 NNP cord-006870-f5w6fw6q 1722 6 years year NNS cord-006870-f5w6fw6q 1722 7 , , , cord-006870-f5w6fw6q 1722 8 GCS GCS NNP cord-006870-f5w6fw6q 1722 9 5 5 CD cord-006870-f5w6fw6q 1722 10 - - SYM cord-006870-f5w6fw6q 1722 11 14 14 CD cord-006870-f5w6fw6q 1722 12 , , , cord-006870-f5w6fw6q 1722 13 baseline baseline JJ cord-006870-f5w6fw6q 1722 14 mRS mRS NNP cord-006870-f5w6fw6q 1722 15 7 7 CD cord-006870-f5w6fw6q 1722 16 , , , cord-006870-f5w6fw6q 1722 17 presenting present VBG cord-006870-f5w6fw6q 1722 18 within within IN cord-006870-f5w6fw6q 1722 19 24 24 CD cord-006870-f5w6fw6q 1722 20 hours hour NNS cord-006870-f5w6fw6q 1722 21 from from IN cord-006870-f5w6fw6q 1722 22 last last JJ cord-006870-f5w6fw6q 1722 23 known know VBN cord-006870-f5w6fw6q 1722 24 well well RB cord-006870-f5w6fw6q 1722 25 and and CC cord-006870-f5w6fw6q 1722 26 found find VBD cord-006870-f5w6fw6q 1722 27 to to TO cord-006870-f5w6fw6q 1722 28 have have VB cord-006870-f5w6fw6q 1722 29 a a DT cord-006870-f5w6fw6q 1722 30 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1722 31 , , , cord-006870-f5w6fw6q 1722 32 CTA cta NN cord-006870-f5w6fw6q 1722 33 - - HYPH cord-006870-f5w6fw6q 1722 34 negative negative JJ cord-006870-f5w6fw6q 1722 35 , , , cord-006870-f5w6fw6q 1722 36 supratentorial supratentorial JJ cord-006870-f5w6fw6q 1722 37 ICH ICH NNP cord-006870-f5w6fw6q 1722 38 ( ( -LRB- cord-006870-f5w6fw6q 1722 39 30 30 CD cord-006870-f5w6fw6q 1722 40 - - SYM cord-006870-f5w6fw6q 1722 41 80 80 CD cord-006870-f5w6fw6q 1722 42 mL ml NN cord-006870-f5w6fw6q 1722 43 ) ) -RRB- cord-006870-f5w6fw6q 1722 44 . . . cord-006870-f5w6fw6q 1723 1 Primary primary JJ cord-006870-f5w6fw6q 1723 2 efficacy efficacy NN cord-006870-f5w6fw6q 1723 3 will will MD cord-006870-f5w6fw6q 1723 4 be be VB cord-006870-f5w6fw6q 1723 5 determined determine VBN cord-006870-f5w6fw6q 1723 6 by by IN cord-006870-f5w6fw6q 1723 7 demonstrating demonstrate VBG cord-006870-f5w6fw6q 1723 8 significant significant JJ cord-006870-f5w6fw6q 1723 9 improvement improvement NN cord-006870-f5w6fw6q 1723 10 in in IN cord-006870-f5w6fw6q 1723 11 the the DT cord-006870-f5w6fw6q 1723 12 mean mean JJ cord-006870-f5w6fw6q 1723 13 utility utility NN cord-006870-f5w6fw6q 1723 14 - - HYPH cord-006870-f5w6fw6q 1723 15 weighted weight VBN cord-006870-f5w6fw6q 1723 16 mRS mrs NN cord-006870-f5w6fw6q 1723 17 at at IN cord-006870-f5w6fw6q 1723 18 180 180 CD cord-006870-f5w6fw6q 1723 19 days day NNS cord-006870-f5w6fw6q 1723 20 after after IN cord-006870-f5w6fw6q 1723 21 enrollment enrollment NN cord-006870-f5w6fw6q 1723 22 . . . cord-006870-f5w6fw6q 1724 1 Economic economic JJ cord-006870-f5w6fw6q 1724 2 effect effect NN cord-006870-f5w6fw6q 1724 3 of of IN cord-006870-f5w6fw6q 1724 4 MIPS MIPS NNP cord-006870-f5w6fw6q 1724 5 will will MD cord-006870-f5w6fw6q 1724 6 be be VB cord-006870-f5w6fw6q 1724 7 determined determine VBN cord-006870-f5w6fw6q 1724 8 by by IN cord-006870-f5w6fw6q 1724 9 quantifying quantify VBG cord-006870-f5w6fw6q 1724 10 the the DT cord-006870-f5w6fw6q 1724 11 cost cost NN cord-006870-f5w6fw6q 1724 12 per per IN cord-006870-f5w6fw6q 1724 13 quality quality NN cord-006870-f5w6fw6q 1724 14 - - HYPH cord-006870-f5w6fw6q 1724 15 adjusted adjust VBN cord-006870-f5w6fw6q 1724 16 life life NN cord-006870-f5w6fw6q 1724 17 - - HYPH cord-006870-f5w6fw6q 1724 18 years year NNS cord-006870-f5w6fw6q 1724 19 gained gain VBN cord-006870-f5w6fw6q 1724 20 at at IN cord-006870-f5w6fw6q 1724 21 pre pre JJ cord-006870-f5w6fw6q 1724 22 - - JJ cord-006870-f5w6fw6q 1724 23 determined determined JJ cord-006870-f5w6fw6q 1724 24 time time NN cord-006870-f5w6fw6q 1724 25 points point NNS cord-006870-f5w6fw6q 1724 26 . . . cord-006870-f5w6fw6q 1725 1 The the DT cord-006870-f5w6fw6q 1725 2 rationale rationale NN cord-006870-f5w6fw6q 1725 3 for for IN cord-006870-f5w6fw6q 1725 4 early early JJ cord-006870-f5w6fw6q 1725 5 intervention intervention NN cord-006870-f5w6fw6q 1725 6 is be VBZ cord-006870-f5w6fw6q 1725 7 to to TO cord-006870-f5w6fw6q 1725 8 interrupt interrupt VB cord-006870-f5w6fw6q 1725 9 the the DT cord-006870-f5w6fw6q 1725 10 time time NN cord-006870-f5w6fw6q 1725 11 - - HYPH cord-006870-f5w6fw6q 1725 12 dependent dependent JJ cord-006870-f5w6fw6q 1725 13 ICH ICH NNP cord-006870-f5w6fw6q 1725 14 related relate VBD cord-006870-f5w6fw6q 1725 15 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 1725 16 caused cause VBN cord-006870-f5w6fw6q 1725 17 by by IN cord-006870-f5w6fw6q 1725 18 mechanical mechanical JJ cord-006870-f5w6fw6q 1725 19 pressures pressure NNS cord-006870-f5w6fw6q 1725 20 and and CC cord-006870-f5w6fw6q 1725 21 the the DT cord-006870-f5w6fw6q 1725 22 pro pro JJ cord-006870-f5w6fw6q 1725 23 - - JJ cord-006870-f5w6fw6q 1725 24 inflammatory inflammatory JJ cord-006870-f5w6fw6q 1725 25 secondary secondary JJ cord-006870-f5w6fw6q 1725 26 cascade cascade NN cord-006870-f5w6fw6q 1725 27 that that WDT cord-006870-f5w6fw6q 1725 28 leads lead VBZ cord-006870-f5w6fw6q 1725 29 to to IN cord-006870-f5w6fw6q 1725 30 worsened worsen VBN cord-006870-f5w6fw6q 1725 31 cellular cellular JJ cord-006870-f5w6fw6q 1725 32 injury injury NN cord-006870-f5w6fw6q 1725 33 and and CC cord-006870-f5w6fw6q 1725 34 edema edema NN cord-006870-f5w6fw6q 1725 35 formation formation NN cord-006870-f5w6fw6q 1725 36 . . . cord-006870-f5w6fw6q 1726 1 The the DT cord-006870-f5w6fw6q 1726 2 planned planned JJ cord-006870-f5w6fw6q 1726 3 enrichment enrichment NN cord-006870-f5w6fw6q 1726 4 strategy strategy NN cord-006870-f5w6fw6q 1726 5 acknowledges acknowledge VBZ cord-006870-f5w6fw6q 1726 6 that that IN cord-006870-f5w6fw6q 1726 7 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 1726 8 in in IN cord-006870-f5w6fw6q 1726 9 varied varied JJ cord-006870-f5w6fw6q 1726 10 locations location NNS cord-006870-f5w6fw6q 1726 11 may may MD cord-006870-f5w6fw6q 1726 12 have have VB cord-006870-f5w6fw6q 1726 13 a a DT cord-006870-f5w6fw6q 1726 14 differential differential JJ cord-006870-f5w6fw6q 1726 15 response response NN cord-006870-f5w6fw6q 1726 16 to to IN cord-006870-f5w6fw6q 1726 17 MIPS MIPS NNP cord-006870-f5w6fw6q 1726 18 . . . cord-006870-f5w6fw6q 1727 1 Study study NN cord-006870-f5w6fw6q 1727 2 adaptation adaptation NN cord-006870-f5w6fw6q 1727 3 , , , cord-006870-f5w6fw6q 1727 4 in in IN cord-006870-f5w6fw6q 1727 5 the the DT cord-006870-f5w6fw6q 1727 6 form form NN cord-006870-f5w6fw6q 1727 7 of of IN cord-006870-f5w6fw6q 1727 8 enrichment enrichment NN cord-006870-f5w6fw6q 1727 9 , , , cord-006870-f5w6fw6q 1727 10 may may MD cord-006870-f5w6fw6q 1727 11 occur occur VB cord-006870-f5w6fw6q 1727 12 if if IN cord-006870-f5w6fw6q 1727 13 pre pre JJ cord-006870-f5w6fw6q 1727 14 - - JJ cord-006870-f5w6fw6q 1727 15 determined determined JJ cord-006870-f5w6fw6q 1727 16 futility futility NN cord-006870-f5w6fw6q 1727 17 rules rule NNS cord-006870-f5w6fw6q 1727 18 are be VBP cord-006870-f5w6fw6q 1727 19 met meet VBN cord-006870-f5w6fw6q 1727 20 for for IN cord-006870-f5w6fw6q 1727 21 the the DT cord-006870-f5w6fw6q 1727 22 primary primary JJ cord-006870-f5w6fw6q 1727 23 outcome outcome NN cord-006870-f5w6fw6q 1727 24 in in IN cord-006870-f5w6fw6q 1727 25 either either DT cord-006870-f5w6fw6q 1727 26 of of IN cord-006870-f5w6fw6q 1727 27 the the DT cord-006870-f5w6fw6q 1727 28 two two CD cord-006870-f5w6fw6q 1727 29 locations location NNS cord-006870-f5w6fw6q 1727 30 . . . cord-006870-f5w6fw6q 1728 1 ENRICH enrich VB cord-006870-f5w6fw6q 1728 2 is be VBZ cord-006870-f5w6fw6q 1728 3 designed design VBN cord-006870-f5w6fw6q 1728 4 to to TO cord-006870-f5w6fw6q 1728 5 establish establish VB cord-006870-f5w6fw6q 1728 6 the the DT cord-006870-f5w6fw6q 1728 7 clinical clinical JJ cord-006870-f5w6fw6q 1728 8 and and CC cord-006870-f5w6fw6q 1728 9 economic economic JJ cord-006870-f5w6fw6q 1728 10 value value NN cord-006870-f5w6fw6q 1728 11 of of IN cord-006870-f5w6fw6q 1728 12 early early JJ cord-006870-f5w6fw6q 1728 13 MIPS MIPS NNP cord-006870-f5w6fw6q 1728 14 in in IN cord-006870-f5w6fw6q 1728 15 the the DT cord-006870-f5w6fw6q 1728 16 treatment treatment NN cord-006870-f5w6fw6q 1728 17 of of IN cord-006870-f5w6fw6q 1728 18 ICH ICH NNP cord-006870-f5w6fw6q 1728 19 . . . cord-006870-f5w6fw6q 1729 1 Enrollment enrollment NN cord-006870-f5w6fw6q 1729 2 was be VBD cord-006870-f5w6fw6q 1729 3 initiated initiate VBN cord-006870-f5w6fw6q 1729 4 in in IN cord-006870-f5w6fw6q 1729 5 December December NNP cord-006870-f5w6fw6q 1729 6 2016 2016 CD cord-006870-f5w6fw6q 1729 7 . . . cord-006870-f5w6fw6q 1730 1 Early early JJ cord-006870-f5w6fw6q 1730 2 seizures seizure NNS cord-006870-f5w6fw6q 1730 3 ( ( -LRB- cord-006870-f5w6fw6q 1730 4 < < NNP cord-006870-f5w6fw6q 1730 5 30 30 CD cord-006870-f5w6fw6q 1730 6 days day NNS cord-006870-f5w6fw6q 1730 7 ) ) -RRB- cord-006870-f5w6fw6q 1730 8 after after IN cord-006870-f5w6fw6q 1730 9 intracerebral intracerebral JJ cord-006870-f5w6fw6q 1730 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1730 11 ( ( -LRB- cord-006870-f5w6fw6q 1730 12 ICH ICH NNP cord-006870-f5w6fw6q 1730 13 ) ) -RRB- cord-006870-f5w6fw6q 1730 14 may may MD cord-006870-f5w6fw6q 1730 15 be be VB cord-006870-f5w6fw6q 1730 16 associated associate VBN cord-006870-f5w6fw6q 1730 17 with with IN cord-006870-f5w6fw6q 1730 18 the the DT cord-006870-f5w6fw6q 1730 19 presence presence NN cord-006870-f5w6fw6q 1730 20 and and CC cord-006870-f5w6fw6q 1730 21 degree degree NN cord-006870-f5w6fw6q 1730 22 of of IN cord-006870-f5w6fw6q 1730 23 perihematomal perihematomal NNP cord-006870-f5w6fw6q 1730 24 cytotoxic cytotoxic JJ cord-006870-f5w6fw6q 1730 25 injury injury NN cord-006870-f5w6fw6q 1730 26 . . . cord-006870-f5w6fw6q 1731 1 We -PRON- PRP cord-006870-f5w6fw6q 1731 2 explored explore VBD cord-006870-f5w6fw6q 1731 3 the the DT cord-006870-f5w6fw6q 1731 4 association association NN cord-006870-f5w6fw6q 1731 5 between between IN cord-006870-f5w6fw6q 1731 6 perihematomal perihematomal NNP cord-006870-f5w6fw6q 1731 7 diffusivity diffusivity NNP cord-006870-f5w6fw6q 1731 8 ( ( -LRB- cord-006870-f5w6fw6q 1731 9 PHD PHD NNP cord-006870-f5w6fw6q 1731 10 ) ) -RRB- cord-006870-f5w6fw6q 1731 11 and and CC cord-006870-f5w6fw6q 1731 12 early early JJ cord-006870-f5w6fw6q 1731 13 seizures seizure NNS cord-006870-f5w6fw6q 1731 14 after after IN cord-006870-f5w6fw6q 1731 15 ICH ICH NNP cord-006870-f5w6fw6q 1731 16 . . . cord-006870-f5w6fw6q 1732 1 Consecutive consecutive JJ cord-006870-f5w6fw6q 1732 2 patients patient NNS cord-006870-f5w6fw6q 1732 3 from from IN cord-006870-f5w6fw6q 1732 4 the the DT cord-006870-f5w6fw6q 1732 5 prospective prospective JJ cord-006870-f5w6fw6q 1732 6 NIH NIH NNP cord-006870-f5w6fw6q 1732 7 funded fund VBN cord-006870-f5w6fw6q 1732 8 DASH dash NN cord-006870-f5w6fw6q 1732 9 study study NN cord-006870-f5w6fw6q 1732 10 ( ( -LRB- cord-006870-f5w6fw6q 1732 11 > > NFP cord-006870-f5w6fw6q 1732 12 18 18 CD cord-006870-f5w6fw6q 1732 13 years year NNS cord-006870-f5w6fw6q 1732 14 , , , cord-006870-f5w6fw6q 1732 15 spontaneous spontaneous JJ cord-006870-f5w6fw6q 1732 16 ICH ICH NNP cord-006870-f5w6fw6q 1732 17 ) ) -RRB- cord-006870-f5w6fw6q 1732 18 were be VBD cord-006870-f5w6fw6q 1732 19 included include VBN cord-006870-f5w6fw6q 1732 20 . . . cord-006870-f5w6fw6q 1733 1 All all DT cord-006870-f5w6fw6q 1733 2 patients patient NNS cord-006870-f5w6fw6q 1733 3 had have VBD cord-006870-f5w6fw6q 1733 4 multimodal multimodal NN cord-006870-f5w6fw6q 1733 5 MRI MRI NNP cord-006870-f5w6fw6q 1733 6 within within IN cord-006870-f5w6fw6q 1733 7 2 2 CD cord-006870-f5w6fw6q 1733 8 weeks week NNS cord-006870-f5w6fw6q 1733 9 . . . cord-006870-f5w6fw6q 1734 1 Perihematomal perihematomal NN cord-006870-f5w6fw6q 1734 2 edema edema NN cord-006870-f5w6fw6q 1734 3 ( ( -LRB- cord-006870-f5w6fw6q 1734 4 PHE PHE NNP cord-006870-f5w6fw6q 1734 5 ) ) -RRB- cord-006870-f5w6fw6q 1734 6 volume volume NN cord-006870-f5w6fw6q 1734 7 was be VBD cord-006870-f5w6fw6q 1734 8 outlined outline VBN cord-006870-f5w6fw6q 1734 9 on on IN cord-006870-f5w6fw6q 1734 10 T2 T2 NNP cord-006870-f5w6fw6q 1734 11 / / SYM cord-006870-f5w6fw6q 1734 12 FLAIR FLAIR NNP cord-006870-f5w6fw6q 1734 13 and and CC cord-006870-f5w6fw6q 1734 14 ICH ICH NNP cord-006870-f5w6fw6q 1734 15 volume volume NN cord-006870-f5w6fw6q 1734 16 on on IN cord-006870-f5w6fw6q 1734 17 GRE GRE NNP cord-006870-f5w6fw6q 1734 18 ; ; : cord-006870-f5w6fw6q 1734 19 these these DT cord-006870-f5w6fw6q 1734 20 and and CC cord-006870-f5w6fw6q 1734 21 ADC ADC NNP cord-006870-f5w6fw6q 1734 22 were be VBD cord-006870-f5w6fw6q 1734 23 coregistered coregistere VBN cord-006870-f5w6fw6q 1734 24 to to TO cord-006870-f5w6fw6q 1734 25 analyze analyze VB cord-006870-f5w6fw6q 1734 26 PHD PHD NNP cord-006870-f5w6fw6q 1734 27 . . . cord-006870-f5w6fw6q 1735 1 EEG EEG NNP cord-006870-f5w6fw6q 1735 2 monitoring monitoring NN cord-006870-f5w6fw6q 1735 3 was be VBD cord-006870-f5w6fw6q 1735 4 performed perform VBN cord-006870-f5w6fw6q 1735 5 for for IN cord-006870-f5w6fw6q 1735 6 clinical clinical JJ cord-006870-f5w6fw6q 1735 7 suspicion suspicion NN cord-006870-f5w6fw6q 1735 8 of of IN cord-006870-f5w6fw6q 1735 9 seizure seizure NN cord-006870-f5w6fw6q 1735 10 . . . cord-006870-f5w6fw6q 1736 1 Mean mean JJ cord-006870-f5w6fw6q 1736 2 ADC ADC NNP cord-006870-f5w6fw6q 1736 3 values value NNS cord-006870-f5w6fw6q 1736 4 of of IN cord-006870-f5w6fw6q 1736 5 PHE PHE NNP cord-006870-f5w6fw6q 1736 6 and and CC cord-006870-f5w6fw6q 1736 7 the the DT cord-006870-f5w6fw6q 1736 8 percentage percentage NN cord-006870-f5w6fw6q 1736 9 of of IN cord-006870-f5w6fw6q 1736 10 PHE PHE NNP cord-006870-f5w6fw6q 1736 11 volume volume NN cord-006870-f5w6fw6q 1736 12 were be VBD cord-006870-f5w6fw6q 1736 13 compared compare VBN cord-006870-f5w6fw6q 1736 14 between between IN cord-006870-f5w6fw6q 1736 15 the the DT cord-006870-f5w6fw6q 1736 16 seizure seizure NN cord-006870-f5w6fw6q 1736 17 and and CC cord-006870-f5w6fw6q 1736 18 no no DT cord-006870-f5w6fw6q 1736 19 - - HYPH cord-006870-f5w6fw6q 1736 20 seizure seizure NN cord-006870-f5w6fw6q 1736 21 groups group NNS cord-006870-f5w6fw6q 1736 22 , , , cord-006870-f5w6fw6q 1736 23 with with IN cord-006870-f5w6fw6q 1736 24 ADC adc NN cord-006870-f5w6fw6q 1736 25 values value NNS cord-006870-f5w6fw6q 1736 26 1200 1200 CD cord-006870-f5w6fw6q 1736 27 as as IN cord-006870-f5w6fw6q 1736 28 vasogenic vasogenic NNP cord-006870-f5w6fw6q 1736 29 edema edema NN cord-006870-f5w6fw6q 1736 30 . . . cord-006870-f5w6fw6q 1737 1 Results result NNS cord-006870-f5w6fw6q 1737 2 26 26 CD cord-006870-f5w6fw6q 1737 3 ( ( -LRB- cord-006870-f5w6fw6q 1737 4 11 11 CD cord-006870-f5w6fw6q 1737 5 % % NN cord-006870-f5w6fw6q 1737 6 ) ) -RRB- cord-006870-f5w6fw6q 1737 7 of of IN cord-006870-f5w6fw6q 1737 8 a a DT cord-006870-f5w6fw6q 1737 9 total total NN cord-006870-f5w6fw6q 1737 10 of of IN cord-006870-f5w6fw6q 1737 11 229 229 CD cord-006870-f5w6fw6q 1737 12 patients patient NNS cord-006870-f5w6fw6q 1737 13 had have VBD cord-006870-f5w6fw6q 1737 14 early early JJ cord-006870-f5w6fw6q 1737 15 seizures seizure NNS cord-006870-f5w6fw6q 1737 16 at at IN cord-006870-f5w6fw6q 1737 17 a a DT cord-006870-f5w6fw6q 1737 18 median median NN cord-006870-f5w6fw6q 1737 19 of of IN cord-006870-f5w6fw6q 1737 20 day day NN cord-006870-f5w6fw6q 1737 21 2 2 CD cord-006870-f5w6fw6q 1737 22 post post NN cord-006870-f5w6fw6q 1737 23 ICH ICH NNP cord-006870-f5w6fw6q 1737 24 . . . cord-006870-f5w6fw6q 1738 1 Mean mean JJ cord-006870-f5w6fw6q 1738 2 ADC ADC NNP cord-006870-f5w6fw6q 1738 3 in in IN cord-006870-f5w6fw6q 1738 4 the the DT cord-006870-f5w6fw6q 1738 5 PHE PHE NNP cord-006870-f5w6fw6q 1738 6 region region NN cord-006870-f5w6fw6q 1738 7 was be VBD cord-006870-f5w6fw6q 1738 8 higher high JJR cord-006870-f5w6fw6q 1738 9 in in IN cord-006870-f5w6fw6q 1738 10 the the DT cord-006870-f5w6fw6q 1738 11 seizure seizure NN cord-006870-f5w6fw6q 1738 12 group group NN cord-006870-f5w6fw6q 1738 13 ( ( -LRB- cord-006870-f5w6fw6q 1738 14 mean mean NNP cord-006870-f5w6fw6q 1738 15 : : : cord-006870-f5w6fw6q 1739 1 1169 1169 CD cord-006870-f5w6fw6q 1739 2 + + CC cord-006870-f5w6fw6q 1740 1 /-127 /-127 NFP cord-006870-f5w6fw6q 1740 2 vs vs IN cord-006870-f5w6fw6q 1740 3 1066 1066 CD cord-006870-f5w6fw6q 1741 1 + + CC cord-006870-f5w6fw6q 1742 1 /-154 /-154 NFP cord-006870-f5w6fw6q 1742 2 , , , cord-006870-f5w6fw6q 1742 3 p=0.001 p=0.001 NNP cord-006870-f5w6fw6q 1742 4 ) ) -RRB- cord-006870-f5w6fw6q 1742 5 . . . cord-006870-f5w6fw6q 1743 1 ICH ICH NNP cord-006870-f5w6fw6q 1743 2 , , , cord-006870-f5w6fw6q 1743 3 absolute absolute JJ cord-006870-f5w6fw6q 1743 4 , , , cord-006870-f5w6fw6q 1743 5 and and CC cord-006870-f5w6fw6q 1743 6 relative relative JJ cord-006870-f5w6fw6q 1743 7 PHE PHE NNP cord-006870-f5w6fw6q 1743 8 volumes volume NNS cord-006870-f5w6fw6q 1743 9 were be VBD cord-006870-f5w6fw6q 1743 10 not not RB cord-006870-f5w6fw6q 1743 11 different different JJ cord-006870-f5w6fw6q 1743 12 between between IN cord-006870-f5w6fw6q 1743 13 groups group NNS cord-006870-f5w6fw6q 1743 14 . . . cord-006870-f5w6fw6q 1744 1 The the DT cord-006870-f5w6fw6q 1744 2 PHE PHE NNP cord-006870-f5w6fw6q 1744 3 of of IN cord-006870-f5w6fw6q 1744 4 the the DT cord-006870-f5w6fw6q 1744 5 seizure seizure NN cord-006870-f5w6fw6q 1744 6 group group NN cord-006870-f5w6fw6q 1744 7 had have VBD cord-006870-f5w6fw6q 1744 8 a a DT cord-006870-f5w6fw6q 1744 9 lower low JJR cord-006870-f5w6fw6q 1744 10 percentage percentage NN cord-006870-f5w6fw6q 1744 11 of of IN cord-006870-f5w6fw6q 1744 12 cytotoxic cytotoxic JJ cord-006870-f5w6fw6q 1744 13 edema edema NN cord-006870-f5w6fw6q 1744 14 ( ( -LRB- cord-006870-f5w6fw6q 1744 15 5 5 CD cord-006870-f5w6fw6q 1744 16 % % NN cord-006870-f5w6fw6q 1744 17 vs vs IN cord-006870-f5w6fw6q 1744 18 8 8 CD cord-006870-f5w6fw6q 1744 19 % % NN cord-006870-f5w6fw6q 1744 20 , , , cord-006870-f5w6fw6q 1744 21 p=0.007 p=0.007 NNP cord-006870-f5w6fw6q 1744 22 ) ) -RRB- cord-006870-f5w6fw6q 1744 23 and and CC cord-006870-f5w6fw6q 1744 24 a a DT cord-006870-f5w6fw6q 1744 25 higher high JJR cord-006870-f5w6fw6q 1744 26 percentage percentage NN cord-006870-f5w6fw6q 1744 27 of of IN cord-006870-f5w6fw6q 1744 28 vasogenic vasogenic NN cord-006870-f5w6fw6q 1744 29 edema edema NN cord-006870-f5w6fw6q 1744 30 ( ( -LRB- cord-006870-f5w6fw6q 1744 31 43 43 CD cord-006870-f5w6fw6q 1744 32 % % NN cord-006870-f5w6fw6q 1744 33 vs vs IN cord-006870-f5w6fw6q 1744 34 30 30 CD cord-006870-f5w6fw6q 1744 35 % % NN cord-006870-f5w6fw6q 1744 36 , , , cord-006870-f5w6fw6q 1744 37 p p NN cord-006870-f5w6fw6q 1744 38 1300 1300 CD cord-006870-f5w6fw6q 1744 39 was be VBD cord-006870-f5w6fw6q 1744 40 the the DT cord-006870-f5w6fw6q 1744 41 most most RBS cord-006870-f5w6fw6q 1744 42 predictive predictive JJ cord-006870-f5w6fw6q 1744 43 of of IN cord-006870-f5w6fw6q 1744 44 seizure seizure NN cord-006870-f5w6fw6q 1744 45 with with IN cord-006870-f5w6fw6q 1744 46 AUC AUC NNP cord-006870-f5w6fw6q 1744 47 = = NFP cord-006870-f5w6fw6q 1745 1 0.73 0.73 CD cord-006870-f5w6fw6q 1745 2 , , , cord-006870-f5w6fw6q 1745 3 though though IN cord-006870-f5w6fw6q 1745 4 ADC ADC NNP cord-006870-f5w6fw6q 1745 5 thresholds threshold NNS cord-006870-f5w6fw6q 1745 6 between between IN cord-006870-f5w6fw6q 1745 7 1200 1200 CD cord-006870-f5w6fw6q 1745 8 - - SYM cord-006870-f5w6fw6q 1745 9 1400 1400 CD cord-006870-f5w6fw6q 1745 10 had have VBD cord-006870-f5w6fw6q 1745 11 largely largely RB cord-006870-f5w6fw6q 1745 12 similar similar JJ cord-006870-f5w6fw6q 1745 13 AUC AUC NNP cord-006870-f5w6fw6q 1745 14 's 's POS cord-006870-f5w6fw6q 1745 15 . . . cord-006870-f5w6fw6q 1746 1 PHE PHE NNP cord-006870-f5w6fw6q 1746 2 volume volume NN cord-006870-f5w6fw6q 1746 3 of of IN cord-006870-f5w6fw6q 1746 4 > > $ cord-006870-f5w6fw6q 1746 5 24 24 CD cord-006870-f5w6fw6q 1746 6 % % NN cord-006870-f5w6fw6q 1746 7 ( ( -LRB- cord-006870-f5w6fw6q 1746 8 of of IN cord-006870-f5w6fw6q 1746 9 ADC ADC NNP cord-006870-f5w6fw6q 1746 10 > > XX cord-006870-f5w6fw6q 1746 11 1300 1300 CD cord-006870-f5w6fw6q 1746 12 ) ) -RRB- cord-006870-f5w6fw6q 1746 13 identified identify VBD cord-006870-f5w6fw6q 1746 14 patients patient NNS cord-006870-f5w6fw6q 1746 15 with with IN cord-006870-f5w6fw6q 1746 16 seizure seizure NN cord-006870-f5w6fw6q 1746 17 with with IN cord-006870-f5w6fw6q 1746 18 sensitivity sensitivity NN cord-006870-f5w6fw6q 1746 19 of of IN cord-006870-f5w6fw6q 1746 20 0.81 0.81 CD cord-006870-f5w6fw6q 1746 21 , , , cord-006870-f5w6fw6q 1746 22 specificity specificity NN cord-006870-f5w6fw6q 1746 23 of of IN cord-006870-f5w6fw6q 1746 24 0.63 0.63 CD cord-006870-f5w6fw6q 1746 25 , , , cord-006870-f5w6fw6q 1746 26 and and CC cord-006870-f5w6fw6q 1746 27 remained remain VBD cord-006870-f5w6fw6q 1746 28 significant significant JJ cord-006870-f5w6fw6q 1746 29 in in IN cord-006870-f5w6fw6q 1746 30 multivariable multivariable JJ cord-006870-f5w6fw6q 1746 31 analysis analysis NN cord-006870-f5w6fw6q 1746 32 . . . cord-006870-f5w6fw6q 1747 1 Patients patient NNS cord-006870-f5w6fw6q 1747 2 with with IN cord-006870-f5w6fw6q 1747 3 early early JJ cord-006870-f5w6fw6q 1747 4 post post JJ cord-006870-f5w6fw6q 1747 5 - - JJ cord-006870-f5w6fw6q 1747 6 ICH ich JJ cord-006870-f5w6fw6q 1747 7 seizures seizure NNS cord-006870-f5w6fw6q 1747 8 have have VBP cord-006870-f5w6fw6q 1747 9 higher high JJR cord-006870-f5w6fw6q 1747 10 mean mean JJ cord-006870-f5w6fw6q 1747 11 perihematomal perihematomal NNP cord-006870-f5w6fw6q 1747 12 ADC ADC NNP cord-006870-f5w6fw6q 1747 13 and and CC cord-006870-f5w6fw6q 1747 14 a a DT cord-006870-f5w6fw6q 1747 15 larger large JJR cord-006870-f5w6fw6q 1747 16 percentage percentage NN cord-006870-f5w6fw6q 1747 17 of of IN cord-006870-f5w6fw6q 1747 18 vasogenic vasogenic NN cord-006870-f5w6fw6q 1747 19 edema edema NN cord-006870-f5w6fw6q 1747 20 in in IN cord-006870-f5w6fw6q 1747 21 the the DT cord-006870-f5w6fw6q 1747 22 perihematomal perihematomal NN cord-006870-f5w6fw6q 1747 23 region region NN cord-006870-f5w6fw6q 1747 24 . . . cord-006870-f5w6fw6q 1748 1 Vasogenic Vasogenic NNP cord-006870-f5w6fw6q 1748 2 edema edema NN cord-006870-f5w6fw6q 1748 3 due due IN cord-006870-f5w6fw6q 1748 4 to to IN cord-006870-f5w6fw6q 1748 5 BBB BBB NNP cord-006870-f5w6fw6q 1748 6 breakdown breakdown NN cord-006870-f5w6fw6q 1748 7 and and CC cord-006870-f5w6fw6q 1748 8 perihematomal perihematomal NN cord-006870-f5w6fw6q 1748 9 inflammation inflammation NN cord-006870-f5w6fw6q 1748 10 rather rather RB cord-006870-f5w6fw6q 1748 11 than than IN cord-006870-f5w6fw6q 1748 12 cytotoxic cytotoxic JJ cord-006870-f5w6fw6q 1748 13 injury injury NN cord-006870-f5w6fw6q 1748 14 is be VBZ cord-006870-f5w6fw6q 1748 15 associated associate VBN cord-006870-f5w6fw6q 1748 16 with with IN cord-006870-f5w6fw6q 1748 17 early early JJ cord-006870-f5w6fw6q 1748 18 post post NN cord-006870-f5w6fw6q 1748 19 ICH ICH NNP cord-006870-f5w6fw6q 1748 20 seizures seizure NNS cord-006870-f5w6fw6q 1748 21 . . . cord-006870-f5w6fw6q 1749 1 Novel novel JJ cord-006870-f5w6fw6q 1749 2 neuroprotective neuroprotective JJ cord-006870-f5w6fw6q 1749 3 treatments treatment NNS cord-006870-f5w6fw6q 1749 4 hold hold VBP cord-006870-f5w6fw6q 1749 5 the the DT cord-006870-f5w6fw6q 1749 6 promise promise NN cord-006870-f5w6fw6q 1749 7 to to TO cord-006870-f5w6fw6q 1749 8 improve improve VB cord-006870-f5w6fw6q 1749 9 patient patient JJ cord-006870-f5w6fw6q 1749 10 outcomes outcome NNS cord-006870-f5w6fw6q 1749 11 by by IN cord-006870-f5w6fw6q 1749 12 broadening broaden VBG cord-006870-f5w6fw6q 1749 13 time time NN cord-006870-f5w6fw6q 1749 14 windows window NNS cord-006870-f5w6fw6q 1749 15 of of IN cord-006870-f5w6fw6q 1749 16 intervention intervention NN cord-006870-f5w6fw6q 1749 17 and and CC cord-006870-f5w6fw6q 1749 18 reducing reduce VBG cord-006870-f5w6fw6q 1749 19 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 1749 20 and and CC cord-006870-f5w6fw6q 1749 21 reperfusion reperfusion NN cord-006870-f5w6fw6q 1749 22 injury injury NN cord-006870-f5w6fw6q 1749 23 in in IN cord-006870-f5w6fw6q 1749 24 the the DT cord-006870-f5w6fw6q 1749 25 era era NN cord-006870-f5w6fw6q 1749 26 of of IN cord-006870-f5w6fw6q 1749 27 mechanical mechanical JJ cord-006870-f5w6fw6q 1749 28 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 1749 29 for for IN cord-006870-f5w6fw6q 1749 30 acute acute JJ cord-006870-f5w6fw6q 1749 31 ischemic ischemic JJ cord-006870-f5w6fw6q 1749 32 stroke stroke NN cord-006870-f5w6fw6q 1749 33 . . . cord-006870-f5w6fw6q 1750 1 Hibernating hibernate VBG cord-006870-f5w6fw6q 1750 2 species specie NNS cord-006870-f5w6fw6q 1750 3 , , , cord-006870-f5w6fw6q 1750 4 such such JJ cord-006870-f5w6fw6q 1750 5 as as IN cord-006870-f5w6fw6q 1750 6 arctic arctic JJ cord-006870-f5w6fw6q 1750 7 ground ground NN cord-006870-f5w6fw6q 1750 8 squirrels squirrel NNS cord-006870-f5w6fw6q 1750 9 ( ( -LRB- cord-006870-f5w6fw6q 1750 10 AGS AGS NNP cord-006870-f5w6fw6q 1750 11 ) ) -RRB- cord-006870-f5w6fw6q 1750 12 , , , cord-006870-f5w6fw6q 1750 13 demonstrate demonstrate VBP cord-006870-f5w6fw6q 1750 14 remarkable remarkable JJ cord-006870-f5w6fw6q 1750 15 resilience resilience NN cord-006870-f5w6fw6q 1750 16 to to IN cord-006870-f5w6fw6q 1750 17 ischemic ischemic JJ cord-006870-f5w6fw6q 1750 18 and and CC cord-006870-f5w6fw6q 1750 19 reperfusion reperfusion NN cord-006870-f5w6fw6q 1750 20 injuries injury NNS cord-006870-f5w6fw6q 1750 21 . . . cord-006870-f5w6fw6q 1751 1 Bioinformatic bioinformatic JJ cord-006870-f5w6fw6q 1751 2 analyses analysis NNS cord-006870-f5w6fw6q 1751 3 of of IN cord-006870-f5w6fw6q 1751 4 genomes genome NNS cord-006870-f5w6fw6q 1751 5 of of IN cord-006870-f5w6fw6q 1751 6 hibernating hibernate VBG cord-006870-f5w6fw6q 1751 7 species species NN cord-006870-f5w6fw6q 1751 8 reveals reveal VBZ cord-006870-f5w6fw6q 1751 9 signatures signature NNS cord-006870-f5w6fw6q 1751 10 of of IN cord-006870-f5w6fw6q 1751 11 convergent convergent JJ cord-006870-f5w6fw6q 1751 12 evolution evolution NN cord-006870-f5w6fw6q 1751 13 in in IN cord-006870-f5w6fw6q 1751 14 genes gene NNS cord-006870-f5w6fw6q 1751 15 regulating regulate VBG cord-006870-f5w6fw6q 1751 16 stability stability NN cord-006870-f5w6fw6q 1751 17 and and CC cord-006870-f5w6fw6q 1751 18 formation formation NN cord-006870-f5w6fw6q 1751 19 of of IN cord-006870-f5w6fw6q 1751 20 mitochondrial mitochondrial JJ cord-006870-f5w6fw6q 1751 21 respirasomes respirasome NNS cord-006870-f5w6fw6q 1751 22 . . . cord-006870-f5w6fw6q 1752 1 Hypoxia hypoxia NN cord-006870-f5w6fw6q 1752 2 pre pre JJ cord-006870-f5w6fw6q 1752 3 - - JJ cord-006870-f5w6fw6q 1752 4 conditioning conditioning JJ cord-006870-f5w6fw6q 1752 5 ( ( -LRB- cord-006870-f5w6fw6q 1752 6 HPC HPC NNP cord-006870-f5w6fw6q 1752 7 ) ) -RRB- cord-006870-f5w6fw6q 1752 8 also also RB cord-006870-f5w6fw6q 1752 9 leads lead VBZ cord-006870-f5w6fw6q 1752 10 to to IN cord-006870-f5w6fw6q 1752 11 improved improve VBN cord-006870-f5w6fw6q 1752 12 survival survival NN cord-006870-f5w6fw6q 1752 13 upon upon IN cord-006870-f5w6fw6q 1752 14 subsequent subsequent JJ cord-006870-f5w6fw6q 1752 15 exposure exposure NN cord-006870-f5w6fw6q 1752 16 to to IN cord-006870-f5w6fw6q 1752 17 hypoxia hypoxia NN cord-006870-f5w6fw6q 1752 18 , , , cord-006870-f5w6fw6q 1752 19 and and CC cord-006870-f5w6fw6q 1752 20 is be VBZ cord-006870-f5w6fw6q 1752 21 associated associate VBN cord-006870-f5w6fw6q 1752 22 with with IN cord-006870-f5w6fw6q 1752 23 increased increase VBN cord-006870-f5w6fw6q 1752 24 stabilization stabilization NN cord-006870-f5w6fw6q 1752 25 of of IN cord-006870-f5w6fw6q 1752 26 respirasomes respirasomes NNP cord-006870-f5w6fw6q 1752 27 . . . cord-006870-f5w6fw6q 1753 1 The the DT cord-006870-f5w6fw6q 1753 2 respirasome respirasome NN cord-006870-f5w6fw6q 1753 3 is be VBZ cord-006870-f5w6fw6q 1753 4 a a DT cord-006870-f5w6fw6q 1753 5 macromolecule macromolecule NN cord-006870-f5w6fw6q 1753 6 consisting consist VBG cord-006870-f5w6fw6q 1753 7 of of IN cord-006870-f5w6fw6q 1753 8 oligomers oligomer NNS cord-006870-f5w6fw6q 1753 9 of of IN cord-006870-f5w6fw6q 1753 10 complex complex NN cord-006870-f5w6fw6q 1753 11 I i NN cord-006870-f5w6fw6q 1753 12 , , , cord-006870-f5w6fw6q 1753 13 III III NNP cord-006870-f5w6fw6q 1753 14 , , , cord-006870-f5w6fw6q 1753 15 and and CC cord-006870-f5w6fw6q 1753 16 IV IV NNP cord-006870-f5w6fw6q 1753 17 . . . cord-006870-f5w6fw6q 1754 1 Cox7a2l Cox7a2l NNP cord-006870-f5w6fw6q 1754 2 is be VBZ cord-006870-f5w6fw6q 1754 3 a a DT cord-006870-f5w6fw6q 1754 4 key key JJ cord-006870-f5w6fw6q 1754 5 mediator mediator NN cord-006870-f5w6fw6q 1754 6 of of IN cord-006870-f5w6fw6q 1754 7 respirasome respirasome NNP cord-006870-f5w6fw6q 1754 8 stability stability NN cord-006870-f5w6fw6q 1754 9 via via IN cord-006870-f5w6fw6q 1754 10 interactions interaction NNS cord-006870-f5w6fw6q 1754 11 with with IN cord-006870-f5w6fw6q 1754 12 Complex Complex NNP cord-006870-f5w6fw6q 1754 13 I I NNP cord-006870-f5w6fw6q 1754 14 and and CC cord-006870-f5w6fw6q 1754 15 III III NNP cord-006870-f5w6fw6q 1754 16 . . . cord-006870-f5w6fw6q 1755 1 In in IN cord-006870-f5w6fw6q 1755 2 this this DT cord-006870-f5w6fw6q 1755 3 study study NN cord-006870-f5w6fw6q 1755 4 , , , cord-006870-f5w6fw6q 1755 5 we -PRON- PRP cord-006870-f5w6fw6q 1755 6 explored explore VBD cord-006870-f5w6fw6q 1755 7 the the DT cord-006870-f5w6fw6q 1755 8 role role NN cord-006870-f5w6fw6q 1755 9 of of IN cord-006870-f5w6fw6q 1755 10 Cox7a2l Cox7a2l NNP cord-006870-f5w6fw6q 1755 11 in in IN cord-006870-f5w6fw6q 1755 12 mediating mediate VBG cord-006870-f5w6fw6q 1755 13 respirasome respirasome JJ cord-006870-f5w6fw6q 1755 14 stabilization stabilization NN cord-006870-f5w6fw6q 1755 15 in in IN cord-006870-f5w6fw6q 1755 16 AGS AGS NNP cord-006870-f5w6fw6q 1755 17 neural neural JJ cord-006870-f5w6fw6q 1755 18 stem stem NN cord-006870-f5w6fw6q 1755 19 and and CC cord-006870-f5w6fw6q 1755 20 progenitor progenitor NN cord-006870-f5w6fw6q 1755 21 cells cell NNS cord-006870-f5w6fw6q 1755 22 ( ( -LRB- cord-006870-f5w6fw6q 1755 23 NSC NSC NNP cord-006870-f5w6fw6q 1755 24 / / SYM cord-006870-f5w6fw6q 1755 25 NPCs npc NNS cord-006870-f5w6fw6q 1755 26 ) ) -RRB- cord-006870-f5w6fw6q 1755 27 as as RB cord-006870-f5w6fw6q 1755 28 well well RB cord-006870-f5w6fw6q 1755 29 as as IN cord-006870-f5w6fw6q 1755 30 mouse mouse NN cord-006870-f5w6fw6q 1755 31 NSC NSC NNP cord-006870-f5w6fw6q 1755 32 / / SYM cord-006870-f5w6fw6q 1755 33 NPCs npc NNS cord-006870-f5w6fw6q 1755 34 exposed expose VBN cord-006870-f5w6fw6q 1755 35 to to IN cord-006870-f5w6fw6q 1755 36 HPC HPC NNP cord-006870-f5w6fw6q 1755 37 . . . cord-006870-f5w6fw6q 1756 1 Respirasome respirasome JJ cord-006870-f5w6fw6q 1756 2 stability stability NN cord-006870-f5w6fw6q 1756 3 was be VBD cord-006870-f5w6fw6q 1756 4 assessed assess VBN cord-006870-f5w6fw6q 1756 5 using use VBG cord-006870-f5w6fw6q 1756 6 blue blue JJ cord-006870-f5w6fw6q 1756 7 native native JJ cord-006870-f5w6fw6q 1756 8 gel gel NN cord-006870-f5w6fw6q 1756 9 electrophoresis electrophoresis NN cord-006870-f5w6fw6q 1756 10 and and CC cord-006870-f5w6fw6q 1756 11 mitochondrial mitochondrial JJ cord-006870-f5w6fw6q 1756 12 metabolism metabolism NN cord-006870-f5w6fw6q 1756 13 assessed assess VBN cord-006870-f5w6fw6q 1756 14 by by IN cord-006870-f5w6fw6q 1756 15 measuring measure VBG cord-006870-f5w6fw6q 1756 16 oxygen oxygen NN cord-006870-f5w6fw6q 1756 17 consumption consumption NN cord-006870-f5w6fw6q 1756 18 in in IN cord-006870-f5w6fw6q 1756 19 vitro vitro FW cord-006870-f5w6fw6q 1756 20 ( ( -LRB- cord-006870-f5w6fw6q 1756 21 Seahorse seahorse JJ cord-006870-f5w6fw6q 1756 22 metabolic metabolic JJ cord-006870-f5w6fw6q 1756 23 analyzer analyzer NN cord-006870-f5w6fw6q 1756 24 ) ) -RRB- cord-006870-f5w6fw6q 1756 25 . . . cord-006870-f5w6fw6q 1757 1 Exposure exposure NN cord-006870-f5w6fw6q 1757 2 to to IN cord-006870-f5w6fw6q 1757 3 mild mild JJ cord-006870-f5w6fw6q 1757 4 hypoxia hypoxia NN cord-006870-f5w6fw6q 1757 5 and and CC cord-006870-f5w6fw6q 1757 6 induction induction NN cord-006870-f5w6fw6q 1757 7 of of IN cord-006870-f5w6fw6q 1757 8 HIF HIF NNP cord-006870-f5w6fw6q 1757 9 leads lead VBZ cord-006870-f5w6fw6q 1757 10 to to IN cord-006870-f5w6fw6q 1757 11 stabilization stabilization NN cord-006870-f5w6fw6q 1757 12 of of IN cord-006870-f5w6fw6q 1757 13 respirasomes respirasomes NNP cord-006870-f5w6fw6q 1757 14 , , , cord-006870-f5w6fw6q 1757 15 upregulation upregulation NN cord-006870-f5w6fw6q 1757 16 of of IN cord-006870-f5w6fw6q 1757 17 HIF HIF NNP cord-006870-f5w6fw6q 1757 18 , , , cord-006870-f5w6fw6q 1757 19 and and CC cord-006870-f5w6fw6q 1757 20 modulation modulation NN cord-006870-f5w6fw6q 1757 21 of of IN cord-006870-f5w6fw6q 1757 22 mitochondrial mitochondrial JJ cord-006870-f5w6fw6q 1757 23 metabolism metabolism NN cord-006870-f5w6fw6q 1757 24 . . . cord-006870-f5w6fw6q 1758 1 Interestingly interestingly RB cord-006870-f5w6fw6q 1758 2 , , , cord-006870-f5w6fw6q 1758 3 overexpression overexpression NN cord-006870-f5w6fw6q 1758 4 of of IN cord-006870-f5w6fw6q 1758 5 the the DT cord-006870-f5w6fw6q 1758 6 AGS AGS NNP cord-006870-f5w6fw6q 1758 7 isoform isoform NN cord-006870-f5w6fw6q 1758 8 of of IN cord-006870-f5w6fw6q 1758 9 Cox7a2l Cox7a2l NNP cord-006870-f5w6fw6q 1758 10 , , , cord-006870-f5w6fw6q 1758 11 which which WDT cord-006870-f5w6fw6q 1758 12 has have VBZ cord-006870-f5w6fw6q 1758 13 amino amino JJ cord-006870-f5w6fw6q 1758 14 acid acid JJ cord-006870-f5w6fw6q 1758 15 substitutions substitution NNS cord-006870-f5w6fw6q 1758 16 in in IN cord-006870-f5w6fw6q 1758 17 residues residue NNS cord-006870-f5w6fw6q 1758 18 mediating mediate VBG cord-006870-f5w6fw6q 1758 19 respirasome respirasome NN cord-006870-f5w6fw6q 1758 20 stability stability NN cord-006870-f5w6fw6q 1758 21 , , , cord-006870-f5w6fw6q 1758 22 recapitulates recapitulate VBZ cord-006870-f5w6fw6q 1758 23 the the DT cord-006870-f5w6fw6q 1758 24 effects effect NNS cord-006870-f5w6fw6q 1758 25 of of IN cord-006870-f5w6fw6q 1758 26 hypoxia hypoxia NN cord-006870-f5w6fw6q 1758 27 on on IN cord-006870-f5w6fw6q 1758 28 respirasome respirasome JJ cord-006870-f5w6fw6q 1758 29 stability stability NN cord-006870-f5w6fw6q 1758 30 and and CC cord-006870-f5w6fw6q 1758 31 mitochondrial mitochondrial JJ cord-006870-f5w6fw6q 1758 32 metabolism metabolism NN cord-006870-f5w6fw6q 1758 33 without without IN cord-006870-f5w6fw6q 1758 34 altering alter VBG cord-006870-f5w6fw6q 1758 35 HIF HIF NNP cord-006870-f5w6fw6q 1758 36 expression expression NN cord-006870-f5w6fw6q 1758 37 . . . cord-006870-f5w6fw6q 1759 1 Targeting target VBG cord-006870-f5w6fw6q 1759 2 respirasome respirasome NN cord-006870-f5w6fw6q 1759 3 stability stability NN cord-006870-f5w6fw6q 1759 4 by by IN cord-006870-f5w6fw6q 1759 5 modulating modulate VBG cord-006870-f5w6fw6q 1759 6 Cox7a2l cox7a2l CD cord-006870-f5w6fw6q 1759 7 is be VBZ cord-006870-f5w6fw6q 1759 8 a a DT cord-006870-f5w6fw6q 1759 9 potentially potentially RB cord-006870-f5w6fw6q 1759 10 novel novel JJ cord-006870-f5w6fw6q 1759 11 neuroprotective neuroprotective JJ cord-006870-f5w6fw6q 1759 12 target target NN cord-006870-f5w6fw6q 1759 13 for for IN cord-006870-f5w6fw6q 1759 14 treatment treatment NN cord-006870-f5w6fw6q 1759 15 of of IN cord-006870-f5w6fw6q 1759 16 ischemic ischemic JJ cord-006870-f5w6fw6q 1759 17 injuries injury NNS cord-006870-f5w6fw6q 1759 18 . . . cord-006870-f5w6fw6q 1760 1 Testing test VBG cord-006870-f5w6fw6q 1760 2 of of IN cord-006870-f5w6fw6q 1760 3 these these DT cord-006870-f5w6fw6q 1760 4 hypotheses hypothesis NNS cord-006870-f5w6fw6q 1760 5 in in IN cord-006870-f5w6fw6q 1760 6 pre pre JJ cord-006870-f5w6fw6q 1760 7 - - JJ cord-006870-f5w6fw6q 1760 8 clinical clinical JJ cord-006870-f5w6fw6q 1760 9 models model NNS cord-006870-f5w6fw6q 1760 10 of of IN cord-006870-f5w6fw6q 1760 11 stroke stroke NN cord-006870-f5w6fw6q 1760 12 is be VBZ cord-006870-f5w6fw6q 1760 13 on on RB cord-006870-f5w6fw6q 1760 14 - - HYPH cord-006870-f5w6fw6q 1760 15 going going NN cord-006870-f5w6fw6q 1760 16 . . . cord-006870-f5w6fw6q 1761 1 Acute acute JJ cord-006870-f5w6fw6q 1761 2 stroke stroke NN cord-006870-f5w6fw6q 1761 3 symptoms symptom NNS cord-006870-f5w6fw6q 1761 4 need need VBP cord-006870-f5w6fw6q 1761 5 timely timely JJ cord-006870-f5w6fw6q 1761 6 diagnostics diagnostic NNS cord-006870-f5w6fw6q 1761 7 in in IN cord-006870-f5w6fw6q 1761 8 order order NN cord-006870-f5w6fw6q 1761 9 to to TO cord-006870-f5w6fw6q 1761 10 ensure ensure VB cord-006870-f5w6fw6q 1761 11 best good JJS cord-006870-f5w6fw6q 1761 12 outcomes outcome NNS cord-006870-f5w6fw6q 1761 13 . . . cord-006870-f5w6fw6q 1762 1 As as IN cord-006870-f5w6fw6q 1762 2 a a DT cord-006870-f5w6fw6q 1762 3 non non JJ cord-006870-f5w6fw6q 1762 4 - - JJ cord-006870-f5w6fw6q 1762 5 academic academic JJ cord-006870-f5w6fw6q 1762 6 , , , cord-006870-f5w6fw6q 1762 7 community community NN cord-006870-f5w6fw6q 1762 8 - - HYPH cord-006870-f5w6fw6q 1762 9 based base VBN cord-006870-f5w6fw6q 1762 10 center center NN cord-006870-f5w6fw6q 1762 11 located locate VBN cord-006870-f5w6fw6q 1762 12 in in IN cord-006870-f5w6fw6q 1762 13 rural rural JJ cord-006870-f5w6fw6q 1762 14 Western Western NNP cord-006870-f5w6fw6q 1762 15 NC NC NNP cord-006870-f5w6fw6q 1762 16 , , , cord-006870-f5w6fw6q 1762 17 where where WRB cord-006870-f5w6fw6q 1762 18 we -PRON- PRP cord-006870-f5w6fw6q 1762 19 are be VBP cord-006870-f5w6fw6q 1762 20 the the DT cord-006870-f5w6fw6q 1762 21 regions region NNS cord-006870-f5w6fw6q 1762 22 only only RB cord-006870-f5w6fw6q 1762 23 Comprehensive Comprehensive NNP cord-006870-f5w6fw6q 1762 24 Stroke Stroke NNP cord-006870-f5w6fw6q 1762 25 Center Center NNP cord-006870-f5w6fw6q 1762 26 , , , cord-006870-f5w6fw6q 1762 27 we -PRON- PRP cord-006870-f5w6fw6q 1762 28 developed develop VBD cord-006870-f5w6fw6q 1762 29 a a DT cord-006870-f5w6fw6q 1762 30 process process NN cord-006870-f5w6fw6q 1762 31 to to TO cord-006870-f5w6fw6q 1762 32 intake intake VB cord-006870-f5w6fw6q 1762 33 stroke stroke NN cord-006870-f5w6fw6q 1762 34 patients patient NNS cord-006870-f5w6fw6q 1762 35 quickly quickly RB cord-006870-f5w6fw6q 1762 36 directly directly RB cord-006870-f5w6fw6q 1762 37 from from IN cord-006870-f5w6fw6q 1762 38 CT CT NNP cord-006870-f5w6fw6q 1762 39 to to IN cord-006870-f5w6fw6q 1762 40 Interventional Interventional NNP cord-006870-f5w6fw6q 1762 41 Radiology Radiology NNP cord-006870-f5w6fw6q 1762 42 when when WRB cord-006870-f5w6fw6q 1762 43 applicable applicable JJ cord-006870-f5w6fw6q 1762 44 . . . cord-006870-f5w6fw6q 1763 1 A a DT cord-006870-f5w6fw6q 1763 2 smooth smooth JJ cord-006870-f5w6fw6q 1763 3 transition transition NN cord-006870-f5w6fw6q 1763 4 reduces reduce VBZ cord-006870-f5w6fw6q 1763 5 the the DT cord-006870-f5w6fw6q 1763 6 quantity quantity NN cord-006870-f5w6fw6q 1763 7 of of IN cord-006870-f5w6fw6q 1763 8 time time NN cord-006870-f5w6fw6q 1763 9 from from IN cord-006870-f5w6fw6q 1763 10 imaging image VBG cord-006870-f5w6fw6q 1763 11 to to IN cord-006870-f5w6fw6q 1763 12 interventional interventional JJ cord-006870-f5w6fw6q 1763 13 suite suite NN cord-006870-f5w6fw6q 1763 14 , , , cord-006870-f5w6fw6q 1763 15 ultimately ultimately RB cord-006870-f5w6fw6q 1763 16 reducing reduce VBG cord-006870-f5w6fw6q 1763 17 the the DT cord-006870-f5w6fw6q 1763 18 time time NN cord-006870-f5w6fw6q 1763 19 it -PRON- PRP cord-006870-f5w6fw6q 1763 20 takes take VBZ cord-006870-f5w6fw6q 1763 21 to to TO cord-006870-f5w6fw6q 1763 22 prepare prepare VB cord-006870-f5w6fw6q 1763 23 to to TO cord-006870-f5w6fw6q 1763 24 actively actively RB cord-006870-f5w6fw6q 1763 25 treat treat VB cord-006870-f5w6fw6q 1763 26 a a DT cord-006870-f5w6fw6q 1763 27 patient patient NN cord-006870-f5w6fw6q 1763 28 . . . cord-006870-f5w6fw6q 1764 1 Interventional Interventional NNP cord-006870-f5w6fw6q 1764 2 Radiology Radiology NNP cord-006870-f5w6fw6q 1764 3 Value Value NNP cord-006870-f5w6fw6q 1764 4 Stream Stream NNP cord-006870-f5w6fw6q 1764 5 Mapping Mapping NNP cord-006870-f5w6fw6q 1764 6 started start VBD cord-006870-f5w6fw6q 1764 7 in in IN cord-006870-f5w6fw6q 1764 8 June June NNP cord-006870-f5w6fw6q 1764 9 2016 2016 CD cord-006870-f5w6fw6q 1764 10 . . . cord-006870-f5w6fw6q 1765 1 Multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 1765 2 team team NN cord-006870-f5w6fw6q 1765 3 worked work VBD cord-006870-f5w6fw6q 1765 4 in in IN cord-006870-f5w6fw6q 1765 5 multiple multiple JJ cord-006870-f5w6fw6q 1765 6 work work NN cord-006870-f5w6fw6q 1765 7 groups group NNS cord-006870-f5w6fw6q 1765 8 to to TO cord-006870-f5w6fw6q 1765 9 design design VB cord-006870-f5w6fw6q 1765 10 and and CC cord-006870-f5w6fw6q 1765 11 create create VB cord-006870-f5w6fw6q 1765 12 " " `` cord-006870-f5w6fw6q 1765 13 Code Code NNP cord-006870-f5w6fw6q 1765 14 IR IR NNP cord-006870-f5w6fw6q 1765 15 Stroke stroke NN cord-006870-f5w6fw6q 1765 16 Now now RB cord-006870-f5w6fw6q 1765 17 " " '' cord-006870-f5w6fw6q 1765 18 . . . cord-006870-f5w6fw6q 1766 1 Flow flow NN cord-006870-f5w6fw6q 1766 2 chart chart NN cord-006870-f5w6fw6q 1766 3 created create VBN cord-006870-f5w6fw6q 1766 4 to to TO cord-006870-f5w6fw6q 1766 5 show show VB cord-006870-f5w6fw6q 1766 6 multiple multiple JJ cord-006870-f5w6fw6q 1766 7 moving move VBG cord-006870-f5w6fw6q 1766 8 parts part NNS cord-006870-f5w6fw6q 1766 9 simultaneously simultaneously RB cord-006870-f5w6fw6q 1766 10 , , , cord-006870-f5w6fw6q 1766 11 to to TO cord-006870-f5w6fw6q 1766 12 streamline streamline VB cord-006870-f5w6fw6q 1766 13 transition transition NN cord-006870-f5w6fw6q 1766 14 from from IN cord-006870-f5w6fw6q 1766 15 ER ER NNP cord-006870-f5w6fw6q 1766 16 ( ( -LRB- cord-006870-f5w6fw6q 1766 17 sometimes sometimes RB cord-006870-f5w6fw6q 1766 18 this this DT cord-006870-f5w6fw6q 1766 19 includes include VBZ cord-006870-f5w6fw6q 1766 20 triage triage NN cord-006870-f5w6fw6q 1766 21 from from IN cord-006870-f5w6fw6q 1766 22 the the DT cord-006870-f5w6fw6q 1766 23 region region NN cord-006870-f5w6fw6q 1766 24 also also RB cord-006870-f5w6fw6q 1766 25 ) ) -RRB- cord-006870-f5w6fw6q 1766 26 to to IN cord-006870-f5w6fw6q 1766 27 IR IR NNP cord-006870-f5w6fw6q 1766 28 . . . cord-006870-f5w6fw6q 1767 1 An an DT cord-006870-f5w6fw6q 1767 2 IR IR NNP cord-006870-f5w6fw6q 1767 3 " " `` cord-006870-f5w6fw6q 1767 4 ready ready JJ cord-006870-f5w6fw6q 1767 5 " " '' cord-006870-f5w6fw6q 1767 6 criteria criterion NNS cord-006870-f5w6fw6q 1767 7 was be VBD cord-006870-f5w6fw6q 1767 8 made make VBN cord-006870-f5w6fw6q 1767 9 , , , cord-006870-f5w6fw6q 1767 10 ER ER NNP cord-006870-f5w6fw6q 1767 11 and and CC cord-006870-f5w6fw6q 1767 12 IR IR NNP cord-006870-f5w6fw6q 1767 13 checklists checklist NNS cord-006870-f5w6fw6q 1767 14 , , , cord-006870-f5w6fw6q 1767 15 followed follow VBN cord-006870-f5w6fw6q 1767 16 by by IN cord-006870-f5w6fw6q 1767 17 post post NN cord-006870-f5w6fw6q 1767 18 procedure procedure NN cord-006870-f5w6fw6q 1767 19 debrief debrief NN cord-006870-f5w6fw6q 1767 20 and and CC cord-006870-f5w6fw6q 1767 21 treatment treatment NN cord-006870-f5w6fw6q 1767 22 plans plan NNS cord-006870-f5w6fw6q 1767 23 / / SYM cord-006870-f5w6fw6q 1767 24 order order NN cord-006870-f5w6fw6q 1767 25 set set VBN cord-006870-f5w6fw6q 1767 26 to to TO cord-006870-f5w6fw6q 1767 27 standardize standardize VB cord-006870-f5w6fw6q 1767 28 care care NN cord-006870-f5w6fw6q 1767 29 and and CC cord-006870-f5w6fw6q 1767 30 documentation documentation NN cord-006870-f5w6fw6q 1767 31 . . . cord-006870-f5w6fw6q 1768 1 First First NNP cord-006870-f5w6fw6q 1768 2 Mock Mock NNP cord-006870-f5w6fw6q 1768 3 Code Code NNP cord-006870-f5w6fw6q 1768 4 IR IR NNP cord-006870-f5w6fw6q 1768 5 was be VBD cord-006870-f5w6fw6q 1768 6 done do VBN cord-006870-f5w6fw6q 1768 7 3/28/17 3/28/17 CD cord-006870-f5w6fw6q 1768 8 , , , cord-006870-f5w6fw6q 1768 9 this this DT cord-006870-f5w6fw6q 1768 10 was be VBD cord-006870-f5w6fw6q 1768 11 critiqued critique VBN cord-006870-f5w6fw6q 1768 12 / / WP cord-006870-f5w6fw6q 1768 13 perfected perfect VBN cord-006870-f5w6fw6q 1768 14 . . . cord-006870-f5w6fw6q 1769 1 " " `` cord-006870-f5w6fw6q 1769 2 Go go VB cord-006870-f5w6fw6q 1769 3 Live live JJ cord-006870-f5w6fw6q 1769 4 " " '' cord-006870-f5w6fw6q 1769 5 date date NN cord-006870-f5w6fw6q 1769 6 : : : cord-006870-f5w6fw6q 1769 7 4/3/17 4/3/17 CD cord-006870-f5w6fw6q 1769 8 . . . cord-006870-f5w6fw6q 1770 1 We -PRON- PRP cord-006870-f5w6fw6q 1770 2 continue continue VBP cord-006870-f5w6fw6q 1770 3 process process NN cord-006870-f5w6fw6q 1770 4 improvement improvement NN cord-006870-f5w6fw6q 1770 5 today today NN cord-006870-f5w6fw6q 1770 6 . . . cord-006870-f5w6fw6q 1771 1 In in IN cord-006870-f5w6fw6q 1771 2 first first JJ cord-006870-f5w6fw6q 1771 3 three three CD cord-006870-f5w6fw6q 1771 4 months month NNS cord-006870-f5w6fw6q 1771 5 , , , cord-006870-f5w6fw6q 1771 6 13 13 CD cord-006870-f5w6fw6q 1771 7 patients patient NNS cord-006870-f5w6fw6q 1771 8 have have VBP cord-006870-f5w6fw6q 1771 9 gone go VBN cord-006870-f5w6fw6q 1771 10 through through IN cord-006870-f5w6fw6q 1771 11 this this DT cord-006870-f5w6fw6q 1771 12 process process NN cord-006870-f5w6fw6q 1771 13 . . . cord-006870-f5w6fw6q 1772 1 Average average JJ cord-006870-f5w6fw6q 1772 2 compliance compliance NN cord-006870-f5w6fw6q 1772 3 for for IN cord-006870-f5w6fw6q 1772 4 goal goal NN cord-006870-f5w6fw6q 1772 5 Door Door NNP cord-006870-f5w6fw6q 1772 6 to to TO cord-006870-f5w6fw6q 1772 7 Puncture puncture VB cord-006870-f5w6fw6q 1773 1 < < XX cord-006870-f5w6fw6q 1773 2 90min 90min NNP cord-006870-f5w6fw6q 1773 3 went go VBD cord-006870-f5w6fw6q 1773 4 from from IN cord-006870-f5w6fw6q 1773 5 78.6 78.6 CD cord-006870-f5w6fw6q 1773 6 % % NN cord-006870-f5w6fw6q 1773 7 to to IN cord-006870-f5w6fw6q 1773 8 100 100 CD cord-006870-f5w6fw6q 1773 9 % % NN cord-006870-f5w6fw6q 1773 10 . . . cord-006870-f5w6fw6q 1774 1 Door door NN cord-006870-f5w6fw6q 1774 2 to to IN cord-006870-f5w6fw6q 1774 3 Groin Groin NNP cord-006870-f5w6fw6q 1774 4 times time NNS cord-006870-f5w6fw6q 1774 5 reduced reduce VBN cord-006870-f5w6fw6q 1774 6 from from IN cord-006870-f5w6fw6q 1774 7 72 72 CD cord-006870-f5w6fw6q 1774 8 minutes minute NNS cord-006870-f5w6fw6q 1774 9 to to IN cord-006870-f5w6fw6q 1774 10 62minutes 62minutes CD cord-006870-f5w6fw6q 1774 11 . . . cord-006870-f5w6fw6q 1775 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1775 2 performance performance NN cord-006870-f5w6fw6q 1775 3 is be VBZ cord-006870-f5w6fw6q 1775 4 26 26 CD cord-006870-f5w6fw6q 1775 5 minutes minute NNS cord-006870-f5w6fw6q 1775 6 quicker quick RBR cord-006870-f5w6fw6q 1775 7 than than IN cord-006870-f5w6fw6q 1775 8 other other JJ cord-006870-f5w6fw6q 1775 9 Comprehensive Comprehensive NNP cord-006870-f5w6fw6q 1775 10 Stroke Stroke NNP cord-006870-f5w6fw6q 1775 11 Centers Centers NNPS cord-006870-f5w6fw6q 1775 12 ( ( -LRB- cord-006870-f5w6fw6q 1775 13 88 88 CD cord-006870-f5w6fw6q 1775 14 m m NN cord-006870-f5w6fw6q 1775 15 avg avg NN cord-006870-f5w6fw6q 1775 16 GWTG GWTG NNP cord-006870-f5w6fw6q 1775 17 database database NN cord-006870-f5w6fw6q 1775 18 ) ) -RRB- cord-006870-f5w6fw6q 1775 19 . . . cord-006870-f5w6fw6q 1776 1 Saved save VBN cord-006870-f5w6fw6q 1776 2 an an DT cord-006870-f5w6fw6q 1776 3 average average NN cord-006870-f5w6fw6q 1776 4 of of IN cord-006870-f5w6fw6q 1776 5 19 19 CD cord-006870-f5w6fw6q 1776 6 million million CD cord-006870-f5w6fw6q 1776 7 neurons neuron NNS cord-006870-f5w6fw6q 1776 8 per per IN cord-006870-f5w6fw6q 1776 9 patient patient NN cord-006870-f5w6fw6q 1776 10 . . . cord-006870-f5w6fw6q 1777 1 Total total NN cord-006870-f5w6fw6q 1777 2 of of IN cord-006870-f5w6fw6q 1777 3 247 247 CD cord-006870-f5w6fw6q 1777 4 million million CD cord-006870-f5w6fw6q 1777 5 neurons neuron NNS cord-006870-f5w6fw6q 1777 6 saved save VBN cord-006870-f5w6fw6q 1777 7 on on IN cord-006870-f5w6fw6q 1777 8 average average JJ cord-006870-f5w6fw6q 1777 9 since since IN cord-006870-f5w6fw6q 1777 10 4/3/17 4/3/17 CD cord-006870-f5w6fw6q 1777 11 ! ! . cord-006870-f5w6fw6q 1778 1 Door door NN cord-006870-f5w6fw6q 1778 2 to to IN cord-006870-f5w6fw6q 1778 3 Groin Groin NNP cord-006870-f5w6fw6q 1778 4 times time NNS cord-006870-f5w6fw6q 1778 5 can can MD cord-006870-f5w6fw6q 1778 6 be be VB cord-006870-f5w6fw6q 1778 7 reduced reduce VBN cord-006870-f5w6fw6q 1778 8 with with IN cord-006870-f5w6fw6q 1778 9 streamline streamline NN cord-006870-f5w6fw6q 1778 10 approach approach NN cord-006870-f5w6fw6q 1778 11 to to TO cord-006870-f5w6fw6q 1778 12 care care VB cord-006870-f5w6fw6q 1778 13 . . . cord-006870-f5w6fw6q 1779 1 Multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 1779 2 team team NN cord-006870-f5w6fw6q 1779 3 approach approach NN cord-006870-f5w6fw6q 1779 4 , , , cord-006870-f5w6fw6q 1779 5 including include VBG cord-006870-f5w6fw6q 1779 6 House House NNP cord-006870-f5w6fw6q 1779 7 Supervisors Supervisors NNPS cord-006870-f5w6fw6q 1779 8 , , , cord-006870-f5w6fw6q 1779 9 Anesthesia Anesthesia NNP cord-006870-f5w6fw6q 1779 10 , , , cord-006870-f5w6fw6q 1779 11 Switch Switch NNP cord-006870-f5w6fw6q 1779 12 - - HYPH cord-006870-f5w6fw6q 1779 13 board board NN cord-006870-f5w6fw6q 1779 14 in in IN cord-006870-f5w6fw6q 1779 15 addition addition NN cord-006870-f5w6fw6q 1779 16 to to IN cord-006870-f5w6fw6q 1779 17 the the DT cord-006870-f5w6fw6q 1779 18 bedside bedside NN cord-006870-f5w6fw6q 1779 19 staff staff NN cord-006870-f5w6fw6q 1779 20 and and CC cord-006870-f5w6fw6q 1779 21 providers provider NNS cord-006870-f5w6fw6q 1779 22 can can MD cord-006870-f5w6fw6q 1779 23 make make VB cord-006870-f5w6fw6q 1779 24 a a DT cord-006870-f5w6fw6q 1779 25 smooth smooth JJ cord-006870-f5w6fw6q 1779 26 transition transition NN cord-006870-f5w6fw6q 1779 27 from from IN cord-006870-f5w6fw6q 1779 28 the the DT cord-006870-f5w6fw6q 1779 29 time time NN cord-006870-f5w6fw6q 1779 30 a a DT cord-006870-f5w6fw6q 1779 31 large large JJ cord-006870-f5w6fw6q 1779 32 vessel vessel NN cord-006870-f5w6fw6q 1779 33 occlusion occlusion NN cord-006870-f5w6fw6q 1779 34 is be VBZ cord-006870-f5w6fw6q 1779 35 identified identify VBN cord-006870-f5w6fw6q 1779 36 to to IN cord-006870-f5w6fw6q 1779 37 getting get VBG cord-006870-f5w6fw6q 1779 38 the the DT cord-006870-f5w6fw6q 1779 39 patient patient NN cord-006870-f5w6fw6q 1779 40 to to IN cord-006870-f5w6fw6q 1779 41 the the DT cord-006870-f5w6fw6q 1779 42 interventional interventional JJ cord-006870-f5w6fw6q 1779 43 suite suite NN cord-006870-f5w6fw6q 1779 44 . . . cord-006870-f5w6fw6q 1780 1 Activation activation NN cord-006870-f5w6fw6q 1780 2 of of IN cord-006870-f5w6fw6q 1780 3 " " `` cord-006870-f5w6fw6q 1780 4 Code Code NNP cord-006870-f5w6fw6q 1780 5 IR IR NNP cord-006870-f5w6fw6q 1780 6 Stroke stroke NN cord-006870-f5w6fw6q 1781 1 Now now RB cord-006870-f5w6fw6q 1781 2 " " `` cord-006870-f5w6fw6q 1781 3 page page NN cord-006870-f5w6fw6q 1781 4 activates activate VBZ cord-006870-f5w6fw6q 1781 5 this this DT cord-006870-f5w6fw6q 1781 6 team team NN cord-006870-f5w6fw6q 1781 7 24/7 24/7 RB cord-006870-f5w6fw6q 1781 8 . . . cord-006870-f5w6fw6q 1782 1 It -PRON- PRP cord-006870-f5w6fw6q 1782 2 is be VBZ cord-006870-f5w6fw6q 1782 3 unknown unknown JJ cord-006870-f5w6fw6q 1782 4 whether whether IN cord-006870-f5w6fw6q 1782 5 antithrombotics antithrombotic NNS cord-006870-f5w6fw6q 1782 6 for for IN cord-006870-f5w6fw6q 1782 7 secondary secondary JJ cord-006870-f5w6fw6q 1782 8 stroke stroke NN cord-006870-f5w6fw6q 1782 9 prevention prevention NN cord-006870-f5w6fw6q 1782 10 in in IN cord-006870-f5w6fw6q 1782 11 patients patient NNS cord-006870-f5w6fw6q 1782 12 with with IN cord-006870-f5w6fw6q 1782 13 acute acute JJ cord-006870-f5w6fw6q 1782 14 ischemic ischemic JJ cord-006870-f5w6fw6q 1782 15 stroke stroke NN cord-006870-f5w6fw6q 1782 16 ( ( -LRB- cord-006870-f5w6fw6q 1782 17 AIS AIS NNP cord-006870-f5w6fw6q 1782 18 ) ) -RRB- cord-006870-f5w6fw6q 1782 19 due due IN cord-006870-f5w6fw6q 1782 20 to to IN cord-006870-f5w6fw6q 1782 21 infective infective JJ cord-006870-f5w6fw6q 1782 22 endocarditis endocarditis NN cord-006870-f5w6fw6q 1783 1 ( ( -LRB- cord-006870-f5w6fw6q 1783 2 IE IE NNP cord-006870-f5w6fw6q 1783 3 ) ) -RRB- cord-006870-f5w6fw6q 1783 4 reduce reduce VB cord-006870-f5w6fw6q 1783 5 the the DT cord-006870-f5w6fw6q 1783 6 rate rate NN cord-006870-f5w6fw6q 1783 7 of of IN cord-006870-f5w6fw6q 1783 8 secondary secondary JJ cord-006870-f5w6fw6q 1783 9 AIS AIS NNP cord-006870-f5w6fw6q 1783 10 or or CC cord-006870-f5w6fw6q 1783 11 increase increase VB cord-006870-f5w6fw6q 1783 12 major major JJ cord-006870-f5w6fw6q 1783 13 bleeding bleeding NN cord-006870-f5w6fw6q 1783 14 . . . cord-006870-f5w6fw6q 1784 1 We -PRON- PRP cord-006870-f5w6fw6q 1784 2 conducted conduct VBD cord-006870-f5w6fw6q 1784 3 a a DT cord-006870-f5w6fw6q 1784 4 multi multi JJ cord-006870-f5w6fw6q 1784 5 - - JJ cord-006870-f5w6fw6q 1784 6 center center JJ cord-006870-f5w6fw6q 1784 7 , , , cord-006870-f5w6fw6q 1784 8 retrospective retrospective JJ cord-006870-f5w6fw6q 1784 9 cohort cohort NN cord-006870-f5w6fw6q 1784 10 study study NN cord-006870-f5w6fw6q 1784 11 from from IN cord-006870-f5w6fw6q 1784 12 2007 2007 CD cord-006870-f5w6fw6q 1784 13 - - SYM cord-006870-f5w6fw6q 1784 14 2015 2015 CD cord-006870-f5w6fw6q 1784 15 of of IN cord-006870-f5w6fw6q 1784 16 patients patient NNS cord-006870-f5w6fw6q 1784 17 with with IN cord-006870-f5w6fw6q 1784 18 AIS AIS NNP cord-006870-f5w6fw6q 1784 19 secondary secondary JJ cord-006870-f5w6fw6q 1784 20 to to IN cord-006870-f5w6fw6q 1784 21 left left JJ cord-006870-f5w6fw6q 1784 22 - - HYPH cord-006870-f5w6fw6q 1784 23 sided sided JJ cord-006870-f5w6fw6q 1784 24 IE ie NN cord-006870-f5w6fw6q 1784 25 , , , cord-006870-f5w6fw6q 1784 26 separated separate VBD cord-006870-f5w6fw6q 1784 27 into into IN cord-006870-f5w6fw6q 1784 28 two two CD cord-006870-f5w6fw6q 1784 29 groups group NNS cord-006870-f5w6fw6q 1784 30 ( ( -LRB- cord-006870-f5w6fw6q 1784 31 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 1784 32 vs vs IN cord-006870-f5w6fw6q 1784 33 no no DT cord-006870-f5w6fw6q 1784 34 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 1784 35 ) ) -RRB- cord-006870-f5w6fw6q 1784 36 . . . cord-006870-f5w6fw6q 1785 1 Antithrombotics antithrombotic NNS cord-006870-f5w6fw6q 1785 2 included include VBD cord-006870-f5w6fw6q 1785 3 antiplatelets antiplatelet NNS cord-006870-f5w6fw6q 1785 4 and/or and/or CC cord-006870-f5w6fw6q 1785 5 therapeutic therapeutic JJ cord-006870-f5w6fw6q 1785 6 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 1785 7 . . . cord-006870-f5w6fw6q 1786 1 The the DT cord-006870-f5w6fw6q 1786 2 primary primary JJ cord-006870-f5w6fw6q 1786 3 outcome outcome NN cord-006870-f5w6fw6q 1786 4 was be VBD cord-006870-f5w6fw6q 1786 5 a a DT cord-006870-f5w6fw6q 1786 6 composite composite NN cord-006870-f5w6fw6q 1786 7 of of IN cord-006870-f5w6fw6q 1786 8 recurrent recurrent JJ cord-006870-f5w6fw6q 1786 9 AIS AIS NNP cord-006870-f5w6fw6q 1786 10 and and CC cord-006870-f5w6fw6q 1786 11 major major JJ cord-006870-f5w6fw6q 1786 12 bleeding bleeding NN cord-006870-f5w6fw6q 1786 13 . . . cord-006870-f5w6fw6q 1787 1 Secondary secondary JJ cord-006870-f5w6fw6q 1787 2 outcomes outcome NNS cord-006870-f5w6fw6q 1787 3 included include VBD cord-006870-f5w6fw6q 1787 4 AIS AIS NNP cord-006870-f5w6fw6q 1787 5 and and CC cord-006870-f5w6fw6q 1787 6 major major JJ cord-006870-f5w6fw6q 1787 7 bleeding bleeding NN cord-006870-f5w6fw6q 1787 8 individually individually RB cord-006870-f5w6fw6q 1787 9 . . . cord-006870-f5w6fw6q 1788 1 A a DT cord-006870-f5w6fw6q 1788 2 binary binary JJ cord-006870-f5w6fw6q 1788 3 logistic logistic JJ cord-006870-f5w6fw6q 1788 4 regression regression NN cord-006870-f5w6fw6q 1788 5 model model NN cord-006870-f5w6fw6q 1788 6 adjusted adjust VBN cord-006870-f5w6fw6q 1788 7 for for IN cord-006870-f5w6fw6q 1788 8 age age NN cord-006870-f5w6fw6q 1788 9 and and CC cord-006870-f5w6fw6q 1788 10 native native JJ cord-006870-f5w6fw6q 1788 11 vs vs IN cord-006870-f5w6fw6q 1788 12 prosthetic prosthetic JJ cord-006870-f5w6fw6q 1788 13 valve valve NN cord-006870-f5w6fw6q 1788 14 involvement involvement NN cord-006870-f5w6fw6q 1788 15 was be VBD cord-006870-f5w6fw6q 1788 16 used use VBN cord-006870-f5w6fw6q 1788 17 for for IN cord-006870-f5w6fw6q 1788 18 outcome outcome NN cord-006870-f5w6fw6q 1788 19 evaluation evaluation NN cord-006870-f5w6fw6q 1788 20 . . . cord-006870-f5w6fw6q 1789 1 The the DT cord-006870-f5w6fw6q 1789 2 final final JJ cord-006870-f5w6fw6q 1789 3 analysis analysis NN cord-006870-f5w6fw6q 1789 4 included include VBD cord-006870-f5w6fw6q 1789 5 123 123 CD cord-006870-f5w6fw6q 1789 6 patients patient NNS cord-006870-f5w6fw6q 1789 7 ( ( -LRB- cord-006870-f5w6fw6q 1789 8 91 91 CD cord-006870-f5w6fw6q 1789 9 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 1789 10 vs vs IN cord-006870-f5w6fw6q 1789 11 32 32 CD cord-006870-f5w6fw6q 1789 12 no no DT cord-006870-f5w6fw6q 1789 13 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 1789 14 ) ) -RRB- cord-006870-f5w6fw6q 1789 15 . . . cord-006870-f5w6fw6q 1790 1 Median median JJ cord-006870-f5w6fw6q 1790 2 age age NN cord-006870-f5w6fw6q 1790 3 was be VBD cord-006870-f5w6fw6q 1790 4 61 61 CD cord-006870-f5w6fw6q 1790 5 years year NNS cord-006870-f5w6fw6q 1790 6 and and CC cord-006870-f5w6fw6q 1790 7 25 25 CD cord-006870-f5w6fw6q 1790 8 ( ( -LRB- cord-006870-f5w6fw6q 1790 9 20 20 CD cord-006870-f5w6fw6q 1790 10 % % NN cord-006870-f5w6fw6q 1790 11 ) ) -RRB- cord-006870-f5w6fw6q 1790 12 patients patient NNS cord-006870-f5w6fw6q 1790 13 had have VBD cord-006870-f5w6fw6q 1790 14 prosthetic prosthetic JJ cord-006870-f5w6fw6q 1790 15 valve valve NN cord-006870-f5w6fw6q 1790 16 infections infection NNS cord-006870-f5w6fw6q 1790 17 . . . cord-006870-f5w6fw6q 1791 1 Infecting infect VBG cord-006870-f5w6fw6q 1791 2 organisms organism NNS cord-006870-f5w6fw6q 1791 3 were be VBD cord-006870-f5w6fw6q 1791 4 mostly mostly RB cord-006870-f5w6fw6q 1791 5 methicillin methicillin JJ cord-006870-f5w6fw6q 1791 6 sensitive sensitive JJ cord-006870-f5w6fw6q 1791 7 S. S. NNP cord-006870-f5w6fw6q 1791 8 aureus aureus NN cord-006870-f5w6fw6q 1791 9 ( ( -LRB- cord-006870-f5w6fw6q 1791 10 29 29 CD cord-006870-f5w6fw6q 1791 11 % % NN cord-006870-f5w6fw6q 1791 12 ) ) -RRB- cord-006870-f5w6fw6q 1791 13 or or CC cord-006870-f5w6fw6q 1791 14 Streptococcus Streptococcus NNP cord-006870-f5w6fw6q 1791 15 spp spp NNS cord-006870-f5w6fw6q 1791 16 . . . cord-006870-f5w6fw6q 1792 1 ( ( -LRB- cord-006870-f5w6fw6q 1792 2 26 26 CD cord-006870-f5w6fw6q 1792 3 % % NN cord-006870-f5w6fw6q 1792 4 ) ) -RRB- cord-006870-f5w6fw6q 1792 5 . . . cord-006870-f5w6fw6q 1793 1 Valve valve NN cord-006870-f5w6fw6q 1793 2 repair repair NN cord-006870-f5w6fw6q 1793 3 / / SYM cord-006870-f5w6fw6q 1793 4 replacement replacement NN cord-006870-f5w6fw6q 1793 5 occurred occur VBD cord-006870-f5w6fw6q 1793 6 in in IN cord-006870-f5w6fw6q 1793 7 34 34 CD cord-006870-f5w6fw6q 1793 8 ( ( -LRB- cord-006870-f5w6fw6q 1793 9 28 28 CD cord-006870-f5w6fw6q 1793 10 % % NN cord-006870-f5w6fw6q 1793 11 ) ) -RRB- cord-006870-f5w6fw6q 1793 12 patients patient NNS cord-006870-f5w6fw6q 1793 13 . . . cord-006870-f5w6fw6q 1794 1 Aspirin aspirin VB cord-006870-f5w6fw6q 1794 2 with with IN cord-006870-f5w6fw6q 1794 3 or or CC cord-006870-f5w6fw6q 1794 4 without without IN cord-006870-f5w6fw6q 1794 5 another another DT cord-006870-f5w6fw6q 1794 6 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 1794 7 ( ( -LRB- cord-006870-f5w6fw6q 1794 8 85 85 CD cord-006870-f5w6fw6q 1794 9 % % NN cord-006870-f5w6fw6q 1794 10 ) ) -RRB- cord-006870-f5w6fw6q 1794 11 was be VBD cord-006870-f5w6fw6q 1794 12 the the DT cord-006870-f5w6fw6q 1794 13 most most RBS cord-006870-f5w6fw6q 1794 14 common common JJ cord-006870-f5w6fw6q 1794 15 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 1794 16 treatment treatment NN cord-006870-f5w6fw6q 1794 17 . . . cord-006870-f5w6fw6q 1795 1 The the DT cord-006870-f5w6fw6q 1795 2 primary primary JJ cord-006870-f5w6fw6q 1795 3 outcome outcome NN cord-006870-f5w6fw6q 1795 4 occurred occur VBD cord-006870-f5w6fw6q 1795 5 in in IN cord-006870-f5w6fw6q 1795 6 25.3 25.3 CD cord-006870-f5w6fw6q 1795 7 % % NN cord-006870-f5w6fw6q 1795 8 vs vs IN cord-006870-f5w6fw6q 1795 9 15.6 15.6 CD cord-006870-f5w6fw6q 1795 10 % % NN cord-006870-f5w6fw6q 1795 11 of of IN cord-006870-f5w6fw6q 1795 12 patients patient NNS cord-006870-f5w6fw6q 1795 13 with with IN cord-006870-f5w6fw6q 1795 14 antithrombotics antithrombotic NNS cord-006870-f5w6fw6q 1795 15 vs vs IN cord-006870-f5w6fw6q 1795 16 no no DT cord-006870-f5w6fw6q 1795 17 antithrombotics antithrombotic NNS cord-006870-f5w6fw6q 1795 18 , , , cord-006870-f5w6fw6q 1795 19 respectively respectively RB cord-006870-f5w6fw6q 1795 20 ( ( -LRB- cord-006870-f5w6fw6q 1795 21 OR or CC cord-006870-f5w6fw6q 1795 22 2.2 2.2 CD cord-006870-f5w6fw6q 1795 23 ; ; : cord-006870-f5w6fw6q 1795 24 95 95 CD cord-006870-f5w6fw6q 1795 25 % % NN cord-006870-f5w6fw6q 1795 26 CI CI NNP cord-006870-f5w6fw6q 1795 27 0.7 0.7 CD cord-006870-f5w6fw6q 1795 28 to to IN cord-006870-f5w6fw6q 1795 29 6.9 6.9 CD cord-006870-f5w6fw6q 1795 30 ) ) -RRB- cord-006870-f5w6fw6q 1795 31 . . . cord-006870-f5w6fw6q 1796 1 AIS AIS NNP cord-006870-f5w6fw6q 1796 2 ( ( -LRB- cord-006870-f5w6fw6q 1796 3 6.6 6.6 CD cord-006870-f5w6fw6q 1796 4 % % NN cord-006870-f5w6fw6q 1796 5 vs vs IN cord-006870-f5w6fw6q 1796 6 2.9 2.9 CD cord-006870-f5w6fw6q 1796 7 % % NN cord-006870-f5w6fw6q 1796 8 ; ; , cord-006870-f5w6fw6q 1796 9 OR or CC cord-006870-f5w6fw6q 1796 10 2.2 2.2 CD cord-006870-f5w6fw6q 1796 11 ; ; : cord-006870-f5w6fw6q 1796 12 95 95 CD cord-006870-f5w6fw6q 1796 13 % % NN cord-006870-f5w6fw6q 1796 14 CI CI NNP cord-006870-f5w6fw6q 1796 15 0.2 0.2 CD cord-006870-f5w6fw6q 1796 16 to to IN cord-006870-f5w6fw6q 1796 17 20 20 CD cord-006870-f5w6fw6q 1796 18 ) ) -RRB- cord-006870-f5w6fw6q 1796 19 and and CC cord-006870-f5w6fw6q 1796 20 major major JJ cord-006870-f5w6fw6q 1796 21 bleeding bleeding NN cord-006870-f5w6fw6q 1796 22 ( ( -LRB- cord-006870-f5w6fw6q 1796 23 18.7 18.7 CD cord-006870-f5w6fw6q 1796 24 % % NN cord-006870-f5w6fw6q 1796 25 vs vs IN cord-006870-f5w6fw6q 1796 26 12.5 12.5 CD cord-006870-f5w6fw6q 1796 27 % % NN cord-006870-f5w6fw6q 1796 28 ; ; : cord-006870-f5w6fw6q 1796 29 OR or CC cord-006870-f5w6fw6q 1796 30 2.3 2.3 CD cord-006870-f5w6fw6q 1796 31 ; ; : cord-006870-f5w6fw6q 1796 32 95 95 CD cord-006870-f5w6fw6q 1796 33 % % NN cord-006870-f5w6fw6q 1796 34 CI CI NNP cord-006870-f5w6fw6q 1796 35 0.7 0.7 CD cord-006870-f5w6fw6q 1796 36 to to IN cord-006870-f5w6fw6q 1796 37 8.1 8.1 CD cord-006870-f5w6fw6q 1796 38 ) ) -RRB- cord-006870-f5w6fw6q 1796 39 were be VBD cord-006870-f5w6fw6q 1796 40 similar similar JJ cord-006870-f5w6fw6q 1796 41 between between IN cord-006870-f5w6fw6q 1796 42 groups group NNS cord-006870-f5w6fw6q 1796 43 . . . cord-006870-f5w6fw6q 1797 1 A a DT cord-006870-f5w6fw6q 1797 2 subgroup subgroup NN cord-006870-f5w6fw6q 1797 3 analysis analysis NN cord-006870-f5w6fw6q 1797 4 of of IN cord-006870-f5w6fw6q 1797 5 aspirin aspirin NN cord-006870-f5w6fw6q 1797 6 monotherapy monotherapy NN cord-006870-f5w6fw6q 1797 7 vs vs IN cord-006870-f5w6fw6q 1797 8 no no DT cord-006870-f5w6fw6q 1797 9 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 1797 10 yielded yield VBD cord-006870-f5w6fw6q 1797 11 similar similar JJ cord-006870-f5w6fw6q 1797 12 results result NNS cord-006870-f5w6fw6q 1797 13 for for IN cord-006870-f5w6fw6q 1797 14 the the DT cord-006870-f5w6fw6q 1797 15 primary primary JJ cord-006870-f5w6fw6q 1797 16 outcome outcome NN cord-006870-f5w6fw6q 1797 17 ( ( -LRB- cord-006870-f5w6fw6q 1797 18 28.6 28.6 CD cord-006870-f5w6fw6q 1797 19 % % NN cord-006870-f5w6fw6q 1797 20 vs vs IN cord-006870-f5w6fw6q 1797 21 15.6 15.6 CD cord-006870-f5w6fw6q 1797 22 % % NN cord-006870-f5w6fw6q 1797 23 ; ; , cord-006870-f5w6fw6q 1797 24 OR or CC cord-006870-f5w6fw6q 1797 25 3.1 3.1 CD cord-006870-f5w6fw6q 1797 26 ; ; . cord-006870-f5w6fw6q 1798 1 95 95 CD cord-006870-f5w6fw6q 1798 2 % % NN cord-006870-f5w6fw6q 1798 3 CI CI NNP cord-006870-f5w6fw6q 1798 4 0.9 0.9 CD cord-006870-f5w6fw6q 1798 5 to to IN cord-006870-f5w6fw6q 1798 6 11.1 11.1 CD cord-006870-f5w6fw6q 1798 7 ) ) -RRB- cord-006870-f5w6fw6q 1798 8 and and CC cord-006870-f5w6fw6q 1798 9 AIS AIS NNP cord-006870-f5w6fw6q 1798 10 ( ( -LRB- cord-006870-f5w6fw6q 1798 11 7.1 7.1 CD cord-006870-f5w6fw6q 1798 12 % % NN cord-006870-f5w6fw6q 1798 13 vs vs IN cord-006870-f5w6fw6q 1798 14 3.1 3.1 CD cord-006870-f5w6fw6q 1798 15 % % NN cord-006870-f5w6fw6q 1798 16 ; ; : cord-006870-f5w6fw6q 1798 17 OR or CC cord-006870-f5w6fw6q 1798 18 2.3 2.3 CD cord-006870-f5w6fw6q 1798 19 ; ; : cord-006870-f5w6fw6q 1798 20 95 95 CD cord-006870-f5w6fw6q 1798 21 % % NN cord-006870-f5w6fw6q 1798 22 CI CI NNP cord-006870-f5w6fw6q 1798 23 0.2 0.2 CD cord-006870-f5w6fw6q 1798 24 to to IN cord-006870-f5w6fw6q 1798 25 25.0 25.0 CD cord-006870-f5w6fw6q 1798 26 ) ) -RRB- cord-006870-f5w6fw6q 1798 27 . . . cord-006870-f5w6fw6q 1799 1 Major major JJ cord-006870-f5w6fw6q 1799 2 bleeding bleeding NN cord-006870-f5w6fw6q 1799 3 was be VBD cord-006870-f5w6fw6q 1799 4 increased increase VBN cord-006870-f5w6fw6q 1799 5 , , , cord-006870-f5w6fw6q 1799 6 however however RB cord-006870-f5w6fw6q 1799 7 ( ( -LRB- cord-006870-f5w6fw6q 1799 8 26.2 26.2 CD cord-006870-f5w6fw6q 1799 9 % % NN cord-006870-f5w6fw6q 1799 10 vs vs IN cord-006870-f5w6fw6q 1799 11 12.5 12.5 CD cord-006870-f5w6fw6q 1799 12 % % NN cord-006870-f5w6fw6q 1799 13 ; ; , cord-006870-f5w6fw6q 1799 14 OR or CC cord-006870-f5w6fw6q 1799 15 4.1 4.1 CD cord-006870-f5w6fw6q 1799 16 ; ; : cord-006870-f5w6fw6q 1799 17 95 95 CD cord-006870-f5w6fw6q 1799 18 % % NN cord-006870-f5w6fw6q 1799 19 CI CI NNP cord-006870-f5w6fw6q 1799 20 1.01 1.01 CD cord-006870-f5w6fw6q 1799 21 to to IN cord-006870-f5w6fw6q 1799 22 16.7 16.7 CD cord-006870-f5w6fw6q 1799 23 ; ; : cord-006870-f5w6fw6q 1799 24 p=0.048 p=0.048 NNP cord-006870-f5w6fw6q 1799 25 ) ) -RRB- cord-006870-f5w6fw6q 1799 26 . . . cord-006870-f5w6fw6q 1800 1 Antithrombotics antithrombotic NNS cord-006870-f5w6fw6q 1800 2 after after IN cord-006870-f5w6fw6q 1800 3 AIS AIS NNP cord-006870-f5w6fw6q 1800 4 secondary secondary JJ cord-006870-f5w6fw6q 1800 5 to to IN cord-006870-f5w6fw6q 1800 6 IE IE NNP cord-006870-f5w6fw6q 1800 7 were be VBD cord-006870-f5w6fw6q 1800 8 not not RB cord-006870-f5w6fw6q 1800 9 associated associate VBN cord-006870-f5w6fw6q 1800 10 with with IN cord-006870-f5w6fw6q 1800 11 a a DT cord-006870-f5w6fw6q 1800 12 decrease decrease NN cord-006870-f5w6fw6q 1800 13 in in IN cord-006870-f5w6fw6q 1800 14 recurrent recurrent JJ cord-006870-f5w6fw6q 1800 15 AIS AIS NNP cord-006870-f5w6fw6q 1800 16 or or CC cord-006870-f5w6fw6q 1800 17 an an DT cord-006870-f5w6fw6q 1800 18 increase increase NN cord-006870-f5w6fw6q 1800 19 in in IN cord-006870-f5w6fw6q 1800 20 major major JJ cord-006870-f5w6fw6q 1800 21 bleeding bleeding NN cord-006870-f5w6fw6q 1800 22 . . . cord-006870-f5w6fw6q 1801 1 Aspirin aspirin NN cord-006870-f5w6fw6q 1801 2 monotherapy monotherapy NN cord-006870-f5w6fw6q 1801 3 was be VBD cord-006870-f5w6fw6q 1801 4 associated associate VBN cord-006870-f5w6fw6q 1801 5 with with IN cord-006870-f5w6fw6q 1801 6 an an DT cord-006870-f5w6fw6q 1801 7 increase increase NN cord-006870-f5w6fw6q 1801 8 in in IN cord-006870-f5w6fw6q 1801 9 major major JJ cord-006870-f5w6fw6q 1801 10 bleeding bleeding NN cord-006870-f5w6fw6q 1801 11 without without IN cord-006870-f5w6fw6q 1801 12 any any DT cord-006870-f5w6fw6q 1801 13 reduction reduction NN cord-006870-f5w6fw6q 1801 14 in in IN cord-006870-f5w6fw6q 1801 15 AIS AIS NNP cord-006870-f5w6fw6q 1801 16 . . . cord-006870-f5w6fw6q 1802 1 Malignant malignant JJ cord-006870-f5w6fw6q 1802 2 Hemispheric Hemispheric NNP cord-006870-f5w6fw6q 1802 3 Stroke Stroke NNP cord-006870-f5w6fw6q 1802 4 ( ( -LRB- cord-006870-f5w6fw6q 1802 5 MHS MHS NNP cord-006870-f5w6fw6q 1802 6 ) ) -RRB- cord-006870-f5w6fw6q 1802 7 represents represent VBZ cord-006870-f5w6fw6q 1802 8 between between IN cord-006870-f5w6fw6q 1802 9 2 2 CD cord-006870-f5w6fw6q 1802 10 - - SYM cord-006870-f5w6fw6q 1802 11 8 8 CD cord-006870-f5w6fw6q 1802 12 % % NN cord-006870-f5w6fw6q 1802 13 of of IN cord-006870-f5w6fw6q 1802 14 all all DT cord-006870-f5w6fw6q 1802 15 hospitalized hospitalize VBN cord-006870-f5w6fw6q 1802 16 ischemic ischemic JJ cord-006870-f5w6fw6q 1802 17 stroke stroke NN cord-006870-f5w6fw6q 1802 18 in in IN cord-006870-f5w6fw6q 1802 19 the the DT cord-006870-f5w6fw6q 1802 20 United United NNP cord-006870-f5w6fw6q 1802 21 States States NNP cord-006870-f5w6fw6q 1802 22 . . . cord-006870-f5w6fw6q 1803 1 Pooled pool VBN cord-006870-f5w6fw6q 1803 2 analysis analysis NN cord-006870-f5w6fw6q 1803 3 of of IN cord-006870-f5w6fw6q 1803 4 3 3 CD cord-006870-f5w6fw6q 1803 5 European european JJ cord-006870-f5w6fw6q 1803 6 studies study NNS cord-006870-f5w6fw6q 1803 7 has have VBZ cord-006870-f5w6fw6q 1803 8 demonstrated demonstrate VBN cord-006870-f5w6fw6q 1803 9 that that IN cord-006870-f5w6fw6q 1803 10 decompressive decompressive JJ cord-006870-f5w6fw6q 1803 11 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 1803 12 ( ( -LRB- cord-006870-f5w6fw6q 1803 13 DCHC DCHC NNP cord-006870-f5w6fw6q 1803 14 ) ) -RRB- cord-006870-f5w6fw6q 1803 15 for for IN cord-006870-f5w6fw6q 1803 16 MHS MHS NNP cord-006870-f5w6fw6q 1803 17 reduces reduce VBZ cord-006870-f5w6fw6q 1803 18 mortality mortality NN cord-006870-f5w6fw6q 1803 19 compared compare VBN cord-006870-f5w6fw6q 1803 20 with with IN cord-006870-f5w6fw6q 1803 21 conservative conservative JJ cord-006870-f5w6fw6q 1803 22 medical medical JJ cord-006870-f5w6fw6q 1803 23 management management NN cord-006870-f5w6fw6q 1803 24 and and CC cord-006870-f5w6fw6q 1803 25 may may MD cord-006870-f5w6fw6q 1803 26 also also RB cord-006870-f5w6fw6q 1803 27 improve improve VB cord-006870-f5w6fw6q 1803 28 functional functional JJ cord-006870-f5w6fw6q 1803 29 outcomes outcome NNS cord-006870-f5w6fw6q 1803 30 . . . cord-006870-f5w6fw6q 1804 1 These these DT cord-006870-f5w6fw6q 1804 2 trials trial NNS cord-006870-f5w6fw6q 1804 3 however however RB cord-006870-f5w6fw6q 1804 4 , , , cord-006870-f5w6fw6q 1804 5 excluded exclude VBD cord-006870-f5w6fw6q 1804 6 patients patient NNS cord-006870-f5w6fw6q 1804 7 with with IN cord-006870-f5w6fw6q 1804 8 major major JJ cord-006870-f5w6fw6q 1804 9 medical medical JJ cord-006870-f5w6fw6q 1804 10 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 1804 11 that that WDT cord-006870-f5w6fw6q 1804 12 might may MD cord-006870-f5w6fw6q 1804 13 confound confound VB cord-006870-f5w6fw6q 1804 14 clinical clinical JJ cord-006870-f5w6fw6q 1804 15 outcomes outcome NNS cord-006870-f5w6fw6q 1804 16 . . . cord-006870-f5w6fw6q 1805 1 APACHE APACHE NNP cord-006870-f5w6fw6q 1805 2 II II NNP cord-006870-f5w6fw6q 1805 3 and and CC cord-006870-f5w6fw6q 1805 4 SOFA sofa NN cord-006870-f5w6fw6q 1805 5 scores score NNS cord-006870-f5w6fw6q 1805 6 are be VBP cord-006870-f5w6fw6q 1805 7 validated validate VBN cord-006870-f5w6fw6q 1805 8 ICU ICU NNP cord-006870-f5w6fw6q 1805 9 scoring score VBG cord-006870-f5w6fw6q 1805 10 systems system NNS cord-006870-f5w6fw6q 1805 11 to to TO cord-006870-f5w6fw6q 1805 12 help help VB cord-006870-f5w6fw6q 1805 13 characterize characterize VB cord-006870-f5w6fw6q 1805 14 disease disease NN cord-006870-f5w6fw6q 1805 15 severity severity NN cord-006870-f5w6fw6q 1805 16 and and CC cord-006870-f5w6fw6q 1805 17 estimated estimate VBN cord-006870-f5w6fw6q 1805 18 hospital hospital NN cord-006870-f5w6fw6q 1805 19 mortality mortality NN cord-006870-f5w6fw6q 1805 20 . . . cord-006870-f5w6fw6q 1806 1 This this DT cord-006870-f5w6fw6q 1806 2 study study NN cord-006870-f5w6fw6q 1806 3 aims aim VBZ cord-006870-f5w6fw6q 1806 4 to to TO cord-006870-f5w6fw6q 1806 5 evaluate evaluate VB cord-006870-f5w6fw6q 1806 6 APACHE APACHE NNP cord-006870-f5w6fw6q 1806 7 II II NNP cord-006870-f5w6fw6q 1806 8 and and CC cord-006870-f5w6fw6q 1806 9 SOFA sofa NN cord-006870-f5w6fw6q 1806 10 scores score NNS cord-006870-f5w6fw6q 1806 11 in in IN cord-006870-f5w6fw6q 1806 12 predicting predict VBG cord-006870-f5w6fw6q 1806 13 outcomes outcome NNS cord-006870-f5w6fw6q 1806 14 for for IN cord-006870-f5w6fw6q 1806 15 patients patient NNS cord-006870-f5w6fw6q 1806 16 undergoing undergo VBG cord-006870-f5w6fw6q 1806 17 DCHC DCHC NNP cord-006870-f5w6fw6q 1806 18 for for IN cord-006870-f5w6fw6q 1806 19 MHS MHS NNP cord-006870-f5w6fw6q 1806 20 . . . cord-006870-f5w6fw6q 1807 1 This this DT cord-006870-f5w6fw6q 1807 2 is be VBZ cord-006870-f5w6fw6q 1807 3 a a DT cord-006870-f5w6fw6q 1807 4 single single JJ cord-006870-f5w6fw6q 1807 5 center center NN cord-006870-f5w6fw6q 1807 6 retrospective retrospective JJ cord-006870-f5w6fw6q 1807 7 analysis analysis NN cord-006870-f5w6fw6q 1807 8 of of IN cord-006870-f5w6fw6q 1807 9 patients patient NNS cord-006870-f5w6fw6q 1807 10 who who WP cord-006870-f5w6fw6q 1807 11 underwent undergo VBD cord-006870-f5w6fw6q 1807 12 early early JJ cord-006870-f5w6fw6q 1807 13 DCHC DCHC NNP cord-006870-f5w6fw6q 1807 14 for for IN cord-006870-f5w6fw6q 1807 15 MHS MHS NNP cord-006870-f5w6fw6q 1807 16 between between IN cord-006870-f5w6fw6q 1807 17 May May NNP cord-006870-f5w6fw6q 1807 18 2010 2010 CD cord-006870-f5w6fw6q 1807 19 through through IN cord-006870-f5w6fw6q 1807 20 January January NNP cord-006870-f5w6fw6q 1807 21 2017 2017 CD cord-006870-f5w6fw6q 1807 22 at at IN cord-006870-f5w6fw6q 1807 23 UNC UNC NNP cord-006870-f5w6fw6q 1807 24 Chapel Chapel NNP cord-006870-f5w6fw6q 1807 25 Hill Hill NNP cord-006870-f5w6fw6q 1807 26 . . . cord-006870-f5w6fw6q 1808 1 APACHE APACHE NNP cord-006870-f5w6fw6q 1808 2 II II NNP cord-006870-f5w6fw6q 1808 3 and and CC cord-006870-f5w6fw6q 1808 4 SOFA sofa NN cord-006870-f5w6fw6q 1808 5 scores score NNS cord-006870-f5w6fw6q 1808 6 were be VBD cord-006870-f5w6fw6q 1808 7 calculated calculate VBN cord-006870-f5w6fw6q 1808 8 for for IN cord-006870-f5w6fw6q 1808 9 the the DT cord-006870-f5w6fw6q 1808 10 date date NN cord-006870-f5w6fw6q 1808 11 of of IN cord-006870-f5w6fw6q 1808 12 admission admission NN cord-006870-f5w6fw6q 1808 13 or or CC cord-006870-f5w6fw6q 1808 14 date date NN cord-006870-f5w6fw6q 1808 15 of of IN cord-006870-f5w6fw6q 1808 16 first first JJ cord-006870-f5w6fw6q 1808 17 presentation presentation NN cord-006870-f5w6fw6q 1808 18 to to IN cord-006870-f5w6fw6q 1808 19 neurologic neurologic JJ cord-006870-f5w6fw6q 1808 20 care care NN cord-006870-f5w6fw6q 1808 21 . . . cord-006870-f5w6fw6q 1809 1 Outcomes outcome NNS cord-006870-f5w6fw6q 1809 2 included include VBD cord-006870-f5w6fw6q 1809 3 mortality mortality NN cord-006870-f5w6fw6q 1809 4 at at IN cord-006870-f5w6fw6q 1809 5 discharge discharge NN cord-006870-f5w6fw6q 1809 6 , , , cord-006870-f5w6fw6q 1809 7 mortality mortality NN cord-006870-f5w6fw6q 1809 8 at at IN cord-006870-f5w6fw6q 1809 9 30 30 CD cord-006870-f5w6fw6q 1809 10 day day NN cord-006870-f5w6fw6q 1809 11 , , , cord-006870-f5w6fw6q 1809 12 and and CC cord-006870-f5w6fw6q 1809 13 functional functional JJ cord-006870-f5w6fw6q 1809 14 outcome outcome NN cord-006870-f5w6fw6q 1809 15 at at IN cord-006870-f5w6fw6q 1809 16 last last JJ cord-006870-f5w6fw6q 1809 17 follow follow NN cord-006870-f5w6fw6q 1809 18 up up RP cord-006870-f5w6fw6q 1809 19 , , , cord-006870-f5w6fw6q 1809 20 up up IN cord-006870-f5w6fw6q 1809 21 to to IN cord-006870-f5w6fw6q 1809 22 one one CD cord-006870-f5w6fw6q 1809 23 year year NN cord-006870-f5w6fw6q 1809 24 . . . cord-006870-f5w6fw6q 1810 1 Multivariate multivariate JJ cord-006870-f5w6fw6q 1810 2 analysis analysis NN cord-006870-f5w6fw6q 1810 3 included include VBD cord-006870-f5w6fw6q 1810 4 timing timing NN cord-006870-f5w6fw6q 1810 5 of of IN cord-006870-f5w6fw6q 1810 6 surgery surgery NN cord-006870-f5w6fw6q 1810 7 , , , cord-006870-f5w6fw6q 1810 8 age age NN cord-006870-f5w6fw6q 1810 9 , , , cord-006870-f5w6fw6q 1810 10 laterality laterality NN cord-006870-f5w6fw6q 1810 11 , , , cord-006870-f5w6fw6q 1810 12 presence presence NN cord-006870-f5w6fw6q 1810 13 of of IN cord-006870-f5w6fw6q 1810 14 midline midline JJ cord-006870-f5w6fw6q 1810 15 shift shift NN cord-006870-f5w6fw6q 1810 16 , , , cord-006870-f5w6fw6q 1810 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1810 18 or or CC cord-006870-f5w6fw6q 1810 19 multiple multiple JJ cord-006870-f5w6fw6q 1810 20 territory territory NN cord-006870-f5w6fw6q 1810 21 infarction infarction NN cord-006870-f5w6fw6q 1810 22 . . . cord-006870-f5w6fw6q 1811 1 We -PRON- PRP cord-006870-f5w6fw6q 1811 2 identified identify VBD cord-006870-f5w6fw6q 1811 3 44 44 CD cord-006870-f5w6fw6q 1811 4 patients patient NNS cord-006870-f5w6fw6q 1811 5 who who WP cord-006870-f5w6fw6q 1811 6 met meet VBD cord-006870-f5w6fw6q 1811 7 inclusion inclusion NN cord-006870-f5w6fw6q 1811 8 and and CC cord-006870-f5w6fw6q 1811 9 exclusion exclusion NN cord-006870-f5w6fw6q 1811 10 criteria criterion NNS cord-006870-f5w6fw6q 1811 11 . . . cord-006870-f5w6fw6q 1812 1 The the DT cord-006870-f5w6fw6q 1812 2 median median JJ cord-006870-f5w6fw6q 1812 3 age age NN cord-006870-f5w6fw6q 1812 4 was be VBD cord-006870-f5w6fw6q 1812 5 58 58 CD cord-006870-f5w6fw6q 1812 6 ( ( -LRB- cord-006870-f5w6fw6q 1812 7 25 25 CD cord-006870-f5w6fw6q 1812 8 to to IN cord-006870-f5w6fw6q 1812 9 78 78 CD cord-006870-f5w6fw6q 1812 10 ) ) -RRB- cord-006870-f5w6fw6q 1812 11 , , , cord-006870-f5w6fw6q 1812 12 -nine -nine CD cord-006870-f5w6fw6q 1812 13 percent percent NN cord-006870-f5w6fw6q 1812 14 of of IN cord-006870-f5w6fw6q 1812 15 patients patient NNS cord-006870-f5w6fw6q 1812 16 received receive VBD cord-006870-f5w6fw6q 1812 17 surgery surgery NN cord-006870-f5w6fw6q 1812 18 by by IN cord-006870-f5w6fw6q 1812 19 hospital hospital NN cord-006870-f5w6fw6q 1812 20 day day NN cord-006870-f5w6fw6q 1812 21 2 2 CD cord-006870-f5w6fw6q 1812 22 . . . cord-006870-f5w6fw6q 1813 1 Full full JJ cord-006870-f5w6fw6q 1813 2 statistical statistical JJ cord-006870-f5w6fw6q 1813 3 analysis analysis NN cord-006870-f5w6fw6q 1813 4 is be VBZ cord-006870-f5w6fw6q 1813 5 pending pende VBG cord-006870-f5w6fw6q 1813 6 . . . cord-006870-f5w6fw6q 1814 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1814 2 hypothesis hypothesis NN cord-006870-f5w6fw6q 1814 3 is be VBZ cord-006870-f5w6fw6q 1814 4 a a DT cord-006870-f5w6fw6q 1814 5 positive positive JJ cord-006870-f5w6fw6q 1814 6 correlation correlation NN cord-006870-f5w6fw6q 1814 7 between between IN cord-006870-f5w6fw6q 1814 8 ICU ICU NNP cord-006870-f5w6fw6q 1814 9 severity severity NN cord-006870-f5w6fw6q 1814 10 scores score NNS cord-006870-f5w6fw6q 1814 11 and and CC cord-006870-f5w6fw6q 1814 12 mortality mortality NN cord-006870-f5w6fw6q 1814 13 . . . cord-006870-f5w6fw6q 1815 1 Given give VBN cord-006870-f5w6fw6q 1815 2 APACHE APACHE NNP cord-006870-f5w6fw6q 1815 3 II II NNP cord-006870-f5w6fw6q 1815 4 and and CC cord-006870-f5w6fw6q 1815 5 SOFA sofa NN cord-006870-f5w6fw6q 1815 6 scores score NNS cord-006870-f5w6fw6q 1815 7 capture capture VBP cord-006870-f5w6fw6q 1815 8 the the DT cord-006870-f5w6fw6q 1815 9 effects effect NNS cord-006870-f5w6fw6q 1815 10 of of IN cord-006870-f5w6fw6q 1815 11 acute acute JJ cord-006870-f5w6fw6q 1815 12 and and CC cord-006870-f5w6fw6q 1815 13 chronic chronic JJ cord-006870-f5w6fw6q 1815 14 disease disease NN cord-006870-f5w6fw6q 1815 15 that that WDT cord-006870-f5w6fw6q 1815 16 would would MD cord-006870-f5w6fw6q 1815 17 affect affect VB cord-006870-f5w6fw6q 1815 18 patient patient JJ cord-006870-f5w6fw6q 1815 19 recovery recovery NN cord-006870-f5w6fw6q 1815 20 , , , cord-006870-f5w6fw6q 1815 21 we -PRON- PRP cord-006870-f5w6fw6q 1815 22 hope hope VBP cord-006870-f5w6fw6q 1815 23 to to TO cord-006870-f5w6fw6q 1815 24 provide provide VB cord-006870-f5w6fw6q 1815 25 a a DT cord-006870-f5w6fw6q 1815 26 more more RBR cord-006870-f5w6fw6q 1815 27 comprehensive comprehensive JJ cord-006870-f5w6fw6q 1815 28 prognostication prognostication NN cord-006870-f5w6fw6q 1815 29 of of IN cord-006870-f5w6fw6q 1815 30 outcomes outcome NNS cord-006870-f5w6fw6q 1815 31 following follow VBG cord-006870-f5w6fw6q 1815 32 surgery surgery NN cord-006870-f5w6fw6q 1815 33 to to TO cord-006870-f5w6fw6q 1815 34 help help VB cord-006870-f5w6fw6q 1815 35 guide guide VB cord-006870-f5w6fw6q 1815 36 physicians physician NNS cord-006870-f5w6fw6q 1815 37 and and CC cord-006870-f5w6fw6q 1815 38 family family NN cord-006870-f5w6fw6q 1815 39 members member NNS cord-006870-f5w6fw6q 1815 40 of of IN cord-006870-f5w6fw6q 1815 41 these these DT cord-006870-f5w6fw6q 1815 42 patients patient NNS cord-006870-f5w6fw6q 1815 43 in in IN cord-006870-f5w6fw6q 1815 44 their -PRON- PRP$ cord-006870-f5w6fw6q 1815 45 decision decision NN cord-006870-f5w6fw6q 1815 46 - - HYPH cord-006870-f5w6fw6q 1815 47 making making NN cord-006870-f5w6fw6q 1815 48 process process NN cord-006870-f5w6fw6q 1815 49 . . . cord-006870-f5w6fw6q 1816 1 We -PRON- PRP cord-006870-f5w6fw6q 1816 2 conducted conduct VBD cord-006870-f5w6fw6q 1816 3 this this DT cord-006870-f5w6fw6q 1816 4 study study NN cord-006870-f5w6fw6q 1816 5 to to TO cord-006870-f5w6fw6q 1816 6 investigate investigate VB cord-006870-f5w6fw6q 1816 7 the the DT cord-006870-f5w6fw6q 1816 8 effects effect NNS cord-006870-f5w6fw6q 1816 9 of of IN cord-006870-f5w6fw6q 1816 10 decompressive decompressive JJ cord-006870-f5w6fw6q 1816 11 craniectomy craniectomy NN cord-006870-f5w6fw6q 1816 12 ( ( -LRB- cord-006870-f5w6fw6q 1816 13 DC DC NNP cord-006870-f5w6fw6q 1816 14 ) ) -RRB- cord-006870-f5w6fw6q 1816 15 combined combine VBN cord-006870-f5w6fw6q 1816 16 with with IN cord-006870-f5w6fw6q 1816 17 hypothermia hypothermia NN cord-006870-f5w6fw6q 1816 18 on on IN cord-006870-f5w6fw6q 1816 19 mortality mortality NN cord-006870-f5w6fw6q 1816 20 and and CC cord-006870-f5w6fw6q 1816 21 neurological neurological JJ cord-006870-f5w6fw6q 1816 22 outcomes outcome NNS cord-006870-f5w6fw6q 1816 23 in in IN cord-006870-f5w6fw6q 1816 24 patients patient NNS cord-006870-f5w6fw6q 1816 25 with with IN cord-006870-f5w6fw6q 1816 26 large large JJ cord-006870-f5w6fw6q 1816 27 hemispheric hemispheric JJ cord-006870-f5w6fw6q 1816 28 infarction infarction NN cord-006870-f5w6fw6q 1816 29 . . . cord-006870-f5w6fw6q 1817 1 Within within IN cord-006870-f5w6fw6q 1817 2 48 48 CD cord-006870-f5w6fw6q 1817 3 hours hour NNS cord-006870-f5w6fw6q 1817 4 of of IN cord-006870-f5w6fw6q 1817 5 symptom symptom NN cord-006870-f5w6fw6q 1817 6 onset onset NN cord-006870-f5w6fw6q 1817 7 , , , cord-006870-f5w6fw6q 1817 8 patients patient NNS cord-006870-f5w6fw6q 1817 9 were be VBD cord-006870-f5w6fw6q 1817 10 randomized randomize VBN cord-006870-f5w6fw6q 1817 11 to to IN cord-006870-f5w6fw6q 1817 12 one one CD cord-006870-f5w6fw6q 1817 13 of of IN cord-006870-f5w6fw6q 1817 14 the the DT cord-006870-f5w6fw6q 1817 15 following follow VBG cord-006870-f5w6fw6q 1817 16 three three CD cord-006870-f5w6fw6q 1817 17 groups group NNS cord-006870-f5w6fw6q 1817 18 : : : cord-006870-f5w6fw6q 1817 19 DC DC NNP cord-006870-f5w6fw6q 1817 20 group group NN cord-006870-f5w6fw6q 1817 21 , , , cord-006870-f5w6fw6q 1817 22 DC DC NNP cord-006870-f5w6fw6q 1817 23 plus plus CC cord-006870-f5w6fw6q 1817 24 head head NN cord-006870-f5w6fw6q 1817 25 - - HYPH cord-006870-f5w6fw6q 1817 26 surface surface NN cord-006870-f5w6fw6q 1817 27 cooling cooling NN cord-006870-f5w6fw6q 1817 28 ( ( -LRB- cord-006870-f5w6fw6q 1817 29 DCSC DCSC NNP cord-006870-f5w6fw6q 1817 30 ) ) -RRB- cord-006870-f5w6fw6q 1817 31 group group NN cord-006870-f5w6fw6q 1817 32 and and CC cord-006870-f5w6fw6q 1817 33 DC DC NNP cord-006870-f5w6fw6q 1817 34 plus plus CC cord-006870-f5w6fw6q 1817 35 endovascular endovascular JJ cord-006870-f5w6fw6q 1817 36 hypothermia hypothermia NN cord-006870-f5w6fw6q 1817 37 ( ( -LRB- cord-006870-f5w6fw6q 1817 38 DCEH DCEH NNP cord-006870-f5w6fw6q 1817 39 ) ) -RRB- cord-006870-f5w6fw6q 1817 40 group group NN cord-006870-f5w6fw6q 1817 41 . . . cord-006870-f5w6fw6q 1818 1 We -PRON- PRP cord-006870-f5w6fw6q 1818 2 combined combine VBD cord-006870-f5w6fw6q 1818 3 the the DT cord-006870-f5w6fw6q 1818 4 data datum NNS cord-006870-f5w6fw6q 1818 5 of of IN cord-006870-f5w6fw6q 1818 6 the the DT cord-006870-f5w6fw6q 1818 7 DCSC DCSC NNP cord-006870-f5w6fw6q 1818 8 and and CC cord-006870-f5w6fw6q 1818 9 DCEH DCEH NNP cord-006870-f5w6fw6q 1818 10 group group NN cord-006870-f5w6fw6q 1818 11 to to IN cord-006870-f5w6fw6q 1818 12 DCH DCH NNP cord-006870-f5w6fw6q 1818 13 group group NN cord-006870-f5w6fw6q 1818 14 during during IN cord-006870-f5w6fw6q 1818 15 analysis analysis NN cord-006870-f5w6fw6q 1818 16 . . . cord-006870-f5w6fw6q 1819 1 The the DT cord-006870-f5w6fw6q 1819 2 primary primary JJ cord-006870-f5w6fw6q 1819 3 endpoints endpoint NNS cord-006870-f5w6fw6q 1819 4 were be VBD cord-006870-f5w6fw6q 1819 5 mortality mortality NN cord-006870-f5w6fw6q 1819 6 and and CC cord-006870-f5w6fw6q 1819 7 modified modify VBN cord-006870-f5w6fw6q 1819 8 Rankin Rankin NNP cord-006870-f5w6fw6q 1819 9 Scale Scale NNP cord-006870-f5w6fw6q 1819 10 ( ( -LRB- cord-006870-f5w6fw6q 1819 11 mRS mRS : cord-006870-f5w6fw6q 1819 12 ) ) -RRB- cord-006870-f5w6fw6q 1819 13 score score VB cord-006870-f5w6fw6q 1819 14 at at IN cord-006870-f5w6fw6q 1819 15 6 6 CD cord-006870-f5w6fw6q 1819 16 months month NNS cord-006870-f5w6fw6q 1819 17 . . . cord-006870-f5w6fw6q 1820 1 There there EX cord-006870-f5w6fw6q 1820 2 were be VBD cord-006870-f5w6fw6q 1820 3 9 9 CD cord-006870-f5w6fw6q 1820 4 patients patient NNS cord-006870-f5w6fw6q 1820 5 in in IN cord-006870-f5w6fw6q 1820 6 the the DT cord-006870-f5w6fw6q 1820 7 DC DC NNP cord-006870-f5w6fw6q 1820 8 group group NN cord-006870-f5w6fw6q 1820 9 , , , cord-006870-f5w6fw6q 1820 10 14 14 CD cord-006870-f5w6fw6q 1820 11 patients patient NNS cord-006870-f5w6fw6q 1820 12 in in IN cord-006870-f5w6fw6q 1820 13 the the DT cord-006870-f5w6fw6q 1820 14 DCSC DCSC NNP cord-006870-f5w6fw6q 1820 15 group group NN cord-006870-f5w6fw6q 1820 16 and and CC cord-006870-f5w6fw6q 1820 17 11 11 CD cord-006870-f5w6fw6q 1820 18 patients patient NNS cord-006870-f5w6fw6q 1820 19 in in IN cord-006870-f5w6fw6q 1820 20 the the DT cord-006870-f5w6fw6q 1820 21 DCEH DCEH NNP cord-006870-f5w6fw6q 1820 22 group group NN cord-006870-f5w6fw6q 1820 23 . . . cord-006870-f5w6fw6q 1821 1 For for IN cord-006870-f5w6fw6q 1821 2 all all DT cord-006870-f5w6fw6q 1821 3 patients patient NNS cord-006870-f5w6fw6q 1821 4 , , , cord-006870-f5w6fw6q 1821 5 the the DT cord-006870-f5w6fw6q 1821 6 mortality mortality NN cord-006870-f5w6fw6q 1821 7 at at IN cord-006870-f5w6fw6q 1821 8 discharge discharge NN cord-006870-f5w6fw6q 1821 9 and and CC cord-006870-f5w6fw6q 1821 10 after after IN cord-006870-f5w6fw6q 1821 11 6 6 CD cord-006870-f5w6fw6q 1821 12 months month NNS cord-006870-f5w6fw6q 1821 13 was be VBD cord-006870-f5w6fw6q 1821 14 8.8 8.8 CD cord-006870-f5w6fw6q 1821 15 % % NN cord-006870-f5w6fw6q 1821 16 ( ( -LRB- cord-006870-f5w6fw6q 1821 17 3/34 3/34 CD cord-006870-f5w6fw6q 1821 18 ) ) -RRB- cord-006870-f5w6fw6q 1821 19 and and CC cord-006870-f5w6fw6q 1821 20 35.3 35.3 CD cord-006870-f5w6fw6q 1821 21 % % NN cord-006870-f5w6fw6q 1821 22 ( ( -LRB- cord-006870-f5w6fw6q 1821 23 12/34 12/34 CD cord-006870-f5w6fw6q 1821 24 ) ) -RRB- cord-006870-f5w6fw6q 1821 25 , , , cord-006870-f5w6fw6q 1821 26 respectively respectively RB cord-006870-f5w6fw6q 1821 27 . . . cord-006870-f5w6fw6q 1822 1 The the DT cord-006870-f5w6fw6q 1822 2 DCH DCH NNP cord-006870-f5w6fw6q 1822 3 group group NN cord-006870-f5w6fw6q 1822 4 had have VBD cord-006870-f5w6fw6q 1822 5 lower low JJR cord-006870-f5w6fw6q 1822 6 mortality mortality NN cord-006870-f5w6fw6q 1822 7 , , , cord-006870-f5w6fw6q 1822 8 but but CC cord-006870-f5w6fw6q 1822 9 the the DT cord-006870-f5w6fw6q 1822 10 difference difference NN cord-006870-f5w6fw6q 1822 11 was be VBD cord-006870-f5w6fw6q 1822 12 not not RB cord-006870-f5w6fw6q 1822 13 statistically statistically RB cord-006870-f5w6fw6q 1822 14 significant significant JJ cord-006870-f5w6fw6q 1822 15 ( ( -LRB- cord-006870-f5w6fw6q 1822 16 at at IN cord-006870-f5w6fw6q 1822 17 discharge discharge NN cord-006870-f5w6fw6q 1822 18 , , , cord-006870-f5w6fw6q 1822 19 4.0 4.0 CD cord-006870-f5w6fw6q 1822 20 % % NN cord-006870-f5w6fw6q 1822 21 vs. vs. NN cord-006870-f5w6fw6q 1822 22 22.2 22.2 CD cord-006870-f5w6fw6q 1822 23 % % NN cord-006870-f5w6fw6q 1822 24 , , , cord-006870-f5w6fw6q 1822 25 P=0.098 P=0.098 NNP cord-006870-f5w6fw6q 1822 26 ; ; : cord-006870-f5w6fw6q 1822 27 6 6 CD cord-006870-f5w6fw6q 1822 28 months month NNS cord-006870-f5w6fw6q 1822 29 , , , cord-006870-f5w6fw6q 1822 30 32.0 32.0 CD cord-006870-f5w6fw6q 1822 31 % % NN cord-006870-f5w6fw6q 1822 32 vs. vs. IN cord-006870-f5w6fw6q 1822 33 44.4 44.4 CD cord-006870-f5w6fw6q 1822 34 % % NN cord-006870-f5w6fw6q 1822 35 , , , cord-006870-f5w6fw6q 1822 36 P=0.449 P=0.449 NNP cord-006870-f5w6fw6q 1822 37 ) ) -RRB- cord-006870-f5w6fw6q 1822 38 . . . cord-006870-f5w6fw6q 1823 1 After after IN cord-006870-f5w6fw6q 1823 2 6 6 CD cord-006870-f5w6fw6q 1823 3 months month NNS cord-006870-f5w6fw6q 1823 4 , , , cord-006870-f5w6fw6q 1823 5 22 22 CD cord-006870-f5w6fw6q 1823 6 patients patient NNS cord-006870-f5w6fw6q 1823 7 survived survive VBD cord-006870-f5w6fw6q 1823 8 , , , cord-006870-f5w6fw6q 1823 9 and and CC cord-006870-f5w6fw6q 1823 10 54.5 54.5 CD cord-006870-f5w6fw6q 1823 11 % % NN cord-006870-f5w6fw6q 1823 12 of of IN cord-006870-f5w6fw6q 1823 13 the the DT cord-006870-f5w6fw6q 1823 14 surviving survive VBG cord-006870-f5w6fw6q 1823 15 patients patient NNS cord-006870-f5w6fw6q 1823 16 had have VBD cord-006870-f5w6fw6q 1823 17 good good JJ cord-006870-f5w6fw6q 1823 18 neurological neurological JJ cord-006870-f5w6fw6q 1823 19 outcomes outcome NNS cord-006870-f5w6fw6q 1823 20 ( ( -LRB- cord-006870-f5w6fw6q 1823 21 mRS mRS `` cord-006870-f5w6fw6q 1823 22 score score NN cord-006870-f5w6fw6q 1823 23 of of IN cord-006870-f5w6fw6q 1823 24 1 1 CD cord-006870-f5w6fw6q 1823 25 - - SYM cord-006870-f5w6fw6q 1823 26 3 3 CD cord-006870-f5w6fw6q 1823 27 ) ) -RRB- cord-006870-f5w6fw6q 1823 28 . . . cord-006870-f5w6fw6q 1824 1 The the DT cord-006870-f5w6fw6q 1824 2 DCH DCH NNP cord-006870-f5w6fw6q 1824 3 group group NN cord-006870-f5w6fw6q 1824 4 had have VBD cord-006870-f5w6fw6q 1824 5 better well JJR cord-006870-f5w6fw6q 1824 6 neurological neurological JJ cord-006870-f5w6fw6q 1824 7 outcomes outcome NNS cord-006870-f5w6fw6q 1824 8 , , , cord-006870-f5w6fw6q 1824 9 but but CC cord-006870-f5w6fw6q 1824 10 this this DT cord-006870-f5w6fw6q 1824 11 difference difference NN cord-006870-f5w6fw6q 1824 12 was be VBD cord-006870-f5w6fw6q 1824 13 also also RB cord-006870-f5w6fw6q 1824 14 not not RB cord-006870-f5w6fw6q 1824 15 statistically statistically RB cord-006870-f5w6fw6q 1824 16 significant significant JJ cord-006870-f5w6fw6q 1824 17 ( ( -LRB- cord-006870-f5w6fw6q 1824 18 10/17 10/17 CD cord-006870-f5w6fw6q 1824 19 , , , cord-006870-f5w6fw6q 1824 20 58.8 58.8 CD cord-006870-f5w6fw6q 1824 21 % % NN cord-006870-f5w6fw6q 1824 22 vs. vs. IN cord-006870-f5w6fw6q 1824 23 2/5 2/5 CD cord-006870-f5w6fw6q 1824 24 , , , cord-006870-f5w6fw6q 1824 25 40.0 40.0 CD cord-006870-f5w6fw6q 1824 26 % % NN cord-006870-f5w6fw6q 1824 27 ; ; : cord-006870-f5w6fw6q 1824 28 P=0.457 P=0.457 NNP cord-006870-f5w6fw6q 1824 29 ) ) -RRB- cord-006870-f5w6fw6q 1824 30 . . . cord-006870-f5w6fw6q 1825 1 The the DT cord-006870-f5w6fw6q 1825 2 total total JJ cord-006870-f5w6fw6q 1825 3 number number NN cord-006870-f5w6fw6q 1825 4 of of IN cord-006870-f5w6fw6q 1825 5 patients patient NNS cord-006870-f5w6fw6q 1825 6 experiencing experience VBG cord-006870-f5w6fw6q 1825 7 complications complication NNS cord-006870-f5w6fw6q 1825 8 in in IN cord-006870-f5w6fw6q 1825 9 the the DT cord-006870-f5w6fw6q 1825 10 DC DC NNP cord-006870-f5w6fw6q 1825 11 group group NN cord-006870-f5w6fw6q 1825 12 and and CC cord-006870-f5w6fw6q 1825 13 the the DT cord-006870-f5w6fw6q 1825 14 DCH DCH NNP cord-006870-f5w6fw6q 1825 15 group group NN cord-006870-f5w6fw6q 1825 16 was be VBD cord-006870-f5w6fw6q 1825 17 15 15 CD cord-006870-f5w6fw6q 1825 18 ( ( -LRB- cord-006870-f5w6fw6q 1825 19 7.2 7.2 CD cord-006870-f5w6fw6q 1825 20 % % NN cord-006870-f5w6fw6q 1825 21 ) ) -RRB- cord-006870-f5w6fw6q 1825 22 and and CC cord-006870-f5w6fw6q 1825 23 59 59 CD cord-006870-f5w6fw6q 1825 24 ( ( -LRB- cord-006870-f5w6fw6q 1825 25 10.3 10.3 CD cord-006870-f5w6fw6q 1825 26 % % NN cord-006870-f5w6fw6q 1825 27 ) ) -RRB- cord-006870-f5w6fw6q 1825 28 , , , cord-006870-f5w6fw6q 1825 29 respectively respectively RB cord-006870-f5w6fw6q 1825 30 . . . cord-006870-f5w6fw6q 1826 1 Treatment treatment NN cord-006870-f5w6fw6q 1826 2 with with IN cord-006870-f5w6fw6q 1826 3 hypothermia hypothermia NN cord-006870-f5w6fw6q 1826 4 led lead VBD cord-006870-f5w6fw6q 1826 5 to to IN cord-006870-f5w6fw6q 1826 6 decreased decrease VBN cord-006870-f5w6fw6q 1826 7 mortality mortality NN cord-006870-f5w6fw6q 1826 8 and and CC cord-006870-f5w6fw6q 1826 9 improved improved JJ cord-006870-f5w6fw6q 1826 10 neurological neurological JJ cord-006870-f5w6fw6q 1826 11 outcomes outcome NNS cord-006870-f5w6fw6q 1826 12 in in IN cord-006870-f5w6fw6q 1826 13 LHI LHI NNP cord-006870-f5w6fw6q 1826 14 patients patient NNS cord-006870-f5w6fw6q 1826 15 who who WP cord-006870-f5w6fw6q 1826 16 received receive VBD cord-006870-f5w6fw6q 1826 17 DC DC NNP cord-006870-f5w6fw6q 1826 18 . . . cord-006870-f5w6fw6q 1827 1 A a DT cord-006870-f5w6fw6q 1827 2 multi multi JJ cord-006870-f5w6fw6q 1827 3 - - JJ cord-006870-f5w6fw6q 1827 4 center center JJ cord-006870-f5w6fw6q 1827 5 RCT RCT NNP cord-006870-f5w6fw6q 1827 6 is be VBZ cord-006870-f5w6fw6q 1827 7 needed need VBN cord-006870-f5w6fw6q 1827 8 to to TO cord-006870-f5w6fw6q 1827 9 confirm confirm VB cord-006870-f5w6fw6q 1827 10 these these DT cord-006870-f5w6fw6q 1827 11 results result NNS cord-006870-f5w6fw6q 1827 12 . . . cord-006870-f5w6fw6q 1828 1 DESTINY DESTINY NNP cord-006870-f5w6fw6q 1828 2 II II NNP cord-006870-f5w6fw6q 1828 3 investigated investigate VBD cord-006870-f5w6fw6q 1828 4 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 1828 5 in in IN cord-006870-f5w6fw6q 1828 6 patients patient NNS cord-006870-f5w6fw6q 1828 7 61-years 61-years CD cord-006870-f5w6fw6q 1828 8 and and CC cord-006870-f5w6fw6q 1828 9 older old JJR cord-006870-f5w6fw6q 1828 10 for for IN cord-006870-f5w6fw6q 1828 11 the the DT cord-006870-f5w6fw6q 1828 12 treatment treatment NN cord-006870-f5w6fw6q 1828 13 of of IN cord-006870-f5w6fw6q 1828 14 malignant malignant JJ cord-006870-f5w6fw6q 1828 15 cerebral cerebral JJ cord-006870-f5w6fw6q 1828 16 edema edema NN cord-006870-f5w6fw6q 1828 17 . . . cord-006870-f5w6fw6q 1829 1 We -PRON- PRP cord-006870-f5w6fw6q 1829 2 sought seek VBD cord-006870-f5w6fw6q 1829 3 to to TO cord-006870-f5w6fw6q 1829 4 describe describe VB cord-006870-f5w6fw6q 1829 5 the the DT cord-006870-f5w6fw6q 1829 6 treatment treatment NN cord-006870-f5w6fw6q 1829 7 effect effect NN cord-006870-f5w6fw6q 1829 8 of of IN cord-006870-f5w6fw6q 1829 9 early early JJ cord-006870-f5w6fw6q 1829 10 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 1829 11 in in IN cord-006870-f5w6fw6q 1829 12 DESTINY DESTINY NNP cord-006870-f5w6fw6q 1829 13 II II NNP cord-006870-f5w6fw6q 1829 14 , , , cord-006870-f5w6fw6q 1829 15 using use VBG cord-006870-f5w6fw6q 1829 16 number number NN cord-006870-f5w6fw6q 1829 17 needed need VBN cord-006870-f5w6fw6q 1829 18 to to TO cord-006870-f5w6fw6q 1829 19 treat treat VB cord-006870-f5w6fw6q 1829 20 to to TO cord-006870-f5w6fw6q 1829 21 benefit benefit VB cord-006870-f5w6fw6q 1829 22 ( ( -LRB- cord-006870-f5w6fw6q 1829 23 NNTB NNTB NNP cord-006870-f5w6fw6q 1829 24 ) ) -RRB- cord-006870-f5w6fw6q 1829 25 and and CC cord-006870-f5w6fw6q 1829 26 benefit benefit VB cord-006870-f5w6fw6q 1829 27 per per IN cord-006870-f5w6fw6q 1829 28 hundred hundred CD cord-006870-f5w6fw6q 1829 29 ( ( -LRB- cord-006870-f5w6fw6q 1829 30 BPH BPH NNP cord-006870-f5w6fw6q 1829 31 ) ) -RRB- cord-006870-f5w6fw6q 1829 32 treated treat VBD cord-006870-f5w6fw6q 1829 33 at at IN cord-006870-f5w6fw6q 1829 34 6 6 CD cord-006870-f5w6fw6q 1829 35 and and CC cord-006870-f5w6fw6q 1829 36 12months 12months CD cord-006870-f5w6fw6q 1829 37 . . . cord-006870-f5w6fw6q 1830 1 As as IN cord-006870-f5w6fw6q 1830 2 an an DT cord-006870-f5w6fw6q 1830 3 mRS mrs NN cord-006870-f5w6fw6q 1830 4 of of IN cord-006870-f5w6fw6q 1830 5 5 5 CD cord-006870-f5w6fw6q 1830 6 is be VBZ cord-006870-f5w6fw6q 1830 7 generally generally RB cord-006870-f5w6fw6q 1830 8 undesirable undesirable JJ cord-006870-f5w6fw6q 1830 9 , , , cord-006870-f5w6fw6q 1830 10 we -PRON- PRP cord-006870-f5w6fw6q 1830 11 also also RB cord-006870-f5w6fw6q 1830 12 present present VBP cord-006870-f5w6fw6q 1830 13 NNTB NNTB NNP cord-006870-f5w6fw6q 1830 14 and and CC cord-006870-f5w6fw6q 1830 15 BPH BPH NNP cord-006870-f5w6fw6q 1830 16 excluding exclude VBG cord-006870-f5w6fw6q 1830 17 this this DT cord-006870-f5w6fw6q 1830 18 outcome outcome NN cord-006870-f5w6fw6q 1830 19 . . . cord-006870-f5w6fw6q 1831 1 For for IN cord-006870-f5w6fw6q 1831 2 all all DT cord-006870-f5w6fw6q 1831 3 possible possible JJ cord-006870-f5w6fw6q 1831 4 dichotomizations dichotomization NNS cord-006870-f5w6fw6q 1831 5 of of IN cord-006870-f5w6fw6q 1831 6 the the DT cord-006870-f5w6fw6q 1831 7 mRS mRS NNP cord-006870-f5w6fw6q 1831 8 , , , cord-006870-f5w6fw6q 1831 9 net net JJ cord-006870-f5w6fw6q 1831 10 NNTB NNTB NNP cord-006870-f5w6fw6q 1831 11 was be VBD cord-006870-f5w6fw6q 1831 12 derived derive VBN cord-006870-f5w6fw6q 1831 13 by by IN cord-006870-f5w6fw6q 1831 14 taking take VBG cord-006870-f5w6fw6q 1831 15 the the DT cord-006870-f5w6fw6q 1831 16 inverse inverse NN cord-006870-f5w6fw6q 1831 17 of of IN cord-006870-f5w6fw6q 1831 18 absolute absolute JJ cord-006870-f5w6fw6q 1831 19 risk risk NN cord-006870-f5w6fw6q 1831 20 difference difference NN cord-006870-f5w6fw6q 1831 21 , , , cord-006870-f5w6fw6q 1831 22 and and CC cord-006870-f5w6fw6q 1831 23 net net JJ cord-006870-f5w6fw6q 1831 24 BPH BPH NNS cord-006870-f5w6fw6q 1831 25 by by IN cord-006870-f5w6fw6q 1831 26 multiplying multiply VBG cord-006870-f5w6fw6q 1831 27 absolute absolute JJ cord-006870-f5w6fw6q 1831 28 risk risk NN cord-006870-f5w6fw6q 1831 29 difference difference NN cord-006870-f5w6fw6q 1831 30 by by IN cord-006870-f5w6fw6q 1831 31 100 100 CD cord-006870-f5w6fw6q 1831 32 . . . cord-006870-f5w6fw6q 1832 1 For for IN cord-006870-f5w6fw6q 1832 2 benefits benefit NNS cord-006870-f5w6fw6q 1832 3 simultaneously simultaneously RB cord-006870-f5w6fw6q 1832 4 across across IN cord-006870-f5w6fw6q 1832 5 all all DT cord-006870-f5w6fw6q 1832 6 disability disability NN cord-006870-f5w6fw6q 1832 7 transitions transition NNS cord-006870-f5w6fw6q 1832 8 on on IN cord-006870-f5w6fw6q 1832 9 the the DT cord-006870-f5w6fw6q 1832 10 mRS mRS NNP cord-006870-f5w6fw6q 1832 11 , , , cord-006870-f5w6fw6q 1832 12 NNTB NNTB NNP cord-006870-f5w6fw6q 1832 13 , , , cord-006870-f5w6fw6q 1832 14 and and CC cord-006870-f5w6fw6q 1832 15 BPH BPH NNP cord-006870-f5w6fw6q 1832 16 , , , cord-006870-f5w6fw6q 1832 17 estimates estimate NNS cord-006870-f5w6fw6q 1832 18 were be VBD cord-006870-f5w6fw6q 1832 19 derived derive VBN cord-006870-f5w6fw6q 1832 20 using use VBG cord-006870-f5w6fw6q 1832 21 joint joint JJ cord-006870-f5w6fw6q 1832 22 outcome outcome NN cord-006870-f5w6fw6q 1832 23 tables table NNS cord-006870-f5w6fw6q 1832 24 : : : cord-006870-f5w6fw6q 1832 25 1 1 LS cord-006870-f5w6fw6q 1832 26 ) ) -RRB- cord-006870-f5w6fw6q 1832 27 algorithmic algorithmic JJ cord-006870-f5w6fw6q 1832 28 minimum minimum NN cord-006870-f5w6fw6q 1832 29 and and CC cord-006870-f5w6fw6q 1832 30 maximum maximum NN cord-006870-f5w6fw6q 1832 31 and and CC cord-006870-f5w6fw6q 1832 32 2 2 LS cord-006870-f5w6fw6q 1832 33 ) ) -RRB- cord-006870-f5w6fw6q 1832 34 four four CD cord-006870-f5w6fw6q 1832 35 independent independent JJ cord-006870-f5w6fw6q 1832 36 experts expert NNS cord-006870-f5w6fw6q 1832 37 . . . cord-006870-f5w6fw6q 1833 1 The the DT cord-006870-f5w6fw6q 1833 2 expert expert NN cord-006870-f5w6fw6q 1833 3 data data NN cord-006870-f5w6fw6q 1833 4 is be VBZ cord-006870-f5w6fw6q 1833 5 presented present VBN cord-006870-f5w6fw6q 1833 6 as as IN cord-006870-f5w6fw6q 1833 7 geometric geometric JJ cord-006870-f5w6fw6q 1833 8 mean mean NN cord-006870-f5w6fw6q 1833 9 . . . cord-006870-f5w6fw6q 1834 1 The the DT cord-006870-f5w6fw6q 1834 2 algorithmic algorithmic JJ cord-006870-f5w6fw6q 1834 3 NNTB nntb NN cord-006870-f5w6fw6q 1834 4 was be VBD cord-006870-f5w6fw6q 1834 5 2.34 2.34 CD cord-006870-f5w6fw6q 1834 6 ( ( -LRB- cord-006870-f5w6fw6q 1834 7 range range NN cord-006870-f5w6fw6q 1834 8 1.89 1.89 CD cord-006870-f5w6fw6q 1834 9 - - HYPH cord-006870-f5w6fw6q 1834 10 2.78 2.78 CD cord-006870-f5w6fw6q 1834 11 ) ) -RRB- cord-006870-f5w6fw6q 1834 12 at at IN cord-006870-f5w6fw6q 1834 13 6-months 6-months CD cord-006870-f5w6fw6q 1834 14 and and CC cord-006870-f5w6fw6q 1834 15 2.71 2.71 CD cord-006870-f5w6fw6q 1834 16 ( ( -LRB- cord-006870-f5w6fw6q 1834 17 2.38 2.38 CD cord-006870-f5w6fw6q 1834 18 - - SYM cord-006870-f5w6fw6q 1834 19 3.03 3.03 CD cord-006870-f5w6fw6q 1834 20 ) ) -RRB- cord-006870-f5w6fw6q 1834 21 at at IN cord-006870-f5w6fw6q 1834 22 12-months 12-months CD cord-006870-f5w6fw6q 1834 23 , , , cord-006870-f5w6fw6q 1834 24 while while IN cord-006870-f5w6fw6q 1834 25 BPH BPH NNP cord-006870-f5w6fw6q 1834 26 was be VBD cord-006870-f5w6fw6q 1834 27 44.5 44.5 CD cord-006870-f5w6fw6q 1834 28 ( ( -LRB- cord-006870-f5w6fw6q 1834 29 36 36 CD cord-006870-f5w6fw6q 1834 30 - - SYM cord-006870-f5w6fw6q 1834 31 53 53 CD cord-006870-f5w6fw6q 1834 32 ) ) -RRB- cord-006870-f5w6fw6q 1834 33 and and CC cord-006870-f5w6fw6q 1834 34 37.5 37.5 CD cord-006870-f5w6fw6q 1834 35 ( ( -LRB- cord-006870-f5w6fw6q 1834 36 33 33 CD cord-006870-f5w6fw6q 1834 37 - - SYM cord-006870-f5w6fw6q 1834 38 42 42 CD cord-006870-f5w6fw6q 1834 39 ) ) -RRB- cord-006870-f5w6fw6q 1834 40 . . . cord-006870-f5w6fw6q 1835 1 The the DT cord-006870-f5w6fw6q 1835 2 expert expert NN cord-006870-f5w6fw6q 1835 3 NNTB nntb NN cord-006870-f5w6fw6q 1835 4 was be VBD cord-006870-f5w6fw6q 1835 5 2.25 2.25 CD cord-006870-f5w6fw6q 1835 6 ( ( -LRB- cord-006870-f5w6fw6q 1835 7 2.08 2.08 CD cord-006870-f5w6fw6q 1835 8 - - SYM cord-006870-f5w6fw6q 1835 9 2.56 2.56 CD cord-006870-f5w6fw6q 1835 10 ) ) -RRB- cord-006870-f5w6fw6q 1835 11 at at IN cord-006870-f5w6fw6q 1835 12 6-months 6-months CD cord-006870-f5w6fw6q 1835 13 and and CC cord-006870-f5w6fw6q 1835 14 2.78 2.78 CD cord-006870-f5w6fw6q 1835 15 ( ( -LRB- cord-006870-f5w6fw6q 1835 16 2.63 2.63 CD cord-006870-f5w6fw6q 1835 17 - - SYM cord-006870-f5w6fw6q 1835 18 2.94 2.94 CD cord-006870-f5w6fw6q 1835 19 ) ) -RRB- cord-006870-f5w6fw6q 1835 20 at at IN cord-006870-f5w6fw6q 1835 21 12-months 12-months CD cord-006870-f5w6fw6q 1835 22 , , , cord-006870-f5w6fw6q 1835 23 and and CC cord-006870-f5w6fw6q 1835 24 the the DT cord-006870-f5w6fw6q 1835 25 BPH BPH NNP cord-006870-f5w6fw6q 1835 26 was be VBD cord-006870-f5w6fw6q 1835 27 44.4 44.4 CD cord-006870-f5w6fw6q 1835 28 ( ( -LRB- cord-006870-f5w6fw6q 1835 29 39 39 CD cord-006870-f5w6fw6q 1835 30 - - SYM cord-006870-f5w6fw6q 1835 31 48 48 CD cord-006870-f5w6fw6q 1835 32 ) ) -RRB- cord-006870-f5w6fw6q 1835 33 , , , cord-006870-f5w6fw6q 1835 34 and and CC cord-006870-f5w6fw6q 1835 35 35.9 35.9 CD cord-006870-f5w6fw6q 1835 36 ( ( -LRB- cord-006870-f5w6fw6q 1835 37 34 34 CD cord-006870-f5w6fw6q 1835 38 - - SYM cord-006870-f5w6fw6q 1835 39 38 38 CD cord-006870-f5w6fw6q 1835 40 ) ) -RRB- cord-006870-f5w6fw6q 1835 41 respectively respectively RB cord-006870-f5w6fw6q 1835 42 . . . cord-006870-f5w6fw6q 1836 1 Excluding exclude VBG cord-006870-f5w6fw6q 1836 2 mRS mrs PRP cord-006870-f5w6fw6q 1836 3 5 5 CD cord-006870-f5w6fw6q 1837 1 The the DT cord-006870-f5w6fw6q 1837 2 algorithmic algorithmic JJ cord-006870-f5w6fw6q 1837 3 NNTB nntb NN cord-006870-f5w6fw6q 1837 4 was be VBD cord-006870-f5w6fw6q 1837 5 4.38 4.38 CD cord-006870-f5w6fw6q 1838 1 ( ( -LRB- cord-006870-f5w6fw6q 1838 2 range range NNP cord-006870-f5w6fw6q 1838 3 4 4 CD cord-006870-f5w6fw6q 1838 4 - - CD cord-006870-f5w6fw6q 1838 5 4.76 4.76 CD cord-006870-f5w6fw6q 1838 6 ) ) -RRB- cord-006870-f5w6fw6q 1838 7 at at IN cord-006870-f5w6fw6q 1838 8 6-months 6-months CD cord-006870-f5w6fw6q 1838 9 and and CC cord-006870-f5w6fw6q 1838 10 4.44 4.44 CD cord-006870-f5w6fw6q 1838 11 ( ( -LRB- cord-006870-f5w6fw6q 1838 12 3.35 3.35 CD cord-006870-f5w6fw6q 1838 13 - - SYM cord-006870-f5w6fw6q 1838 14 4.55 4.55 CD cord-006870-f5w6fw6q 1838 15 ) ) -RRB- cord-006870-f5w6fw6q 1838 16 at at IN cord-006870-f5w6fw6q 1838 17 12-months 12-months CD cord-006870-f5w6fw6q 1838 18 , , , cord-006870-f5w6fw6q 1838 19 while while IN cord-006870-f5w6fw6q 1838 20 BPH BPH NNP cord-006870-f5w6fw6q 1838 21 was be VBD cord-006870-f5w6fw6q 1838 22 23 23 CD cord-006870-f5w6fw6q 1838 23 ( ( -LRB- cord-006870-f5w6fw6q 1838 24 21 21 CD cord-006870-f5w6fw6q 1838 25 - - SYM cord-006870-f5w6fw6q 1838 26 25 25 CD cord-006870-f5w6fw6q 1838 27 ) ) -RRB- cord-006870-f5w6fw6q 1838 28 and and CC cord-006870-f5w6fw6q 1838 29 22.5 22.5 CD cord-006870-f5w6fw6q 1838 30 ( ( -LRB- cord-006870-f5w6fw6q 1838 31 22 22 CD cord-006870-f5w6fw6q 1838 32 - - SYM cord-006870-f5w6fw6q 1838 33 23 23 CD cord-006870-f5w6fw6q 1838 34 ) ) -RRB- cord-006870-f5w6fw6q 1838 35 . . . cord-006870-f5w6fw6q 1839 1 The the DT cord-006870-f5w6fw6q 1839 2 expert expert NN cord-006870-f5w6fw6q 1839 3 NNTB nntb NN cord-006870-f5w6fw6q 1839 4 was be VBD cord-006870-f5w6fw6q 1839 5 4.36 4.36 CD cord-006870-f5w6fw6q 1839 6 ( ( -LRB- cord-006870-f5w6fw6q 1839 7 4.0 4.0 CD cord-006870-f5w6fw6q 1839 8 - - SYM cord-006870-f5w6fw6q 1839 9 4.76 4.76 CD cord-006870-f5w6fw6q 1839 10 ) ) -RRB- cord-006870-f5w6fw6q 1839 11 at at IN cord-006870-f5w6fw6q 1839 12 6-months 6-months CD cord-006870-f5w6fw6q 1839 13 , , , cord-006870-f5w6fw6q 1839 14 and and CC cord-006870-f5w6fw6q 1839 15 4.4 4.4 CD cord-006870-f5w6fw6q 1839 16 ( ( -LRB- cord-006870-f5w6fw6q 1839 17 4.35 4.35 CD cord-006870-f5w6fw6q 1839 18 - - SYM cord-006870-f5w6fw6q 1839 19 4.54 4.54 CD cord-006870-f5w6fw6q 1839 20 ) ) -RRB- cord-006870-f5w6fw6q 1839 21 at at IN cord-006870-f5w6fw6q 1839 22 12-months 12-months CD cord-006870-f5w6fw6q 1839 23 , , , cord-006870-f5w6fw6q 1839 24 and and CC cord-006870-f5w6fw6q 1839 25 BPH BPH NNP cord-006870-f5w6fw6q 1839 26 was be VBD cord-006870-f5w6fw6q 1839 27 22.9 22.9 CD cord-006870-f5w6fw6q 1839 28 ( ( -LRB- cord-006870-f5w6fw6q 1839 29 21 21 CD cord-006870-f5w6fw6q 1839 30 - - SYM cord-006870-f5w6fw6q 1839 31 25 25 CD cord-006870-f5w6fw6q 1839 32 ) ) -RRB- cord-006870-f5w6fw6q 1839 33 and and CC cord-006870-f5w6fw6q 1839 34 22.7 22.7 CD cord-006870-f5w6fw6q 1839 35 ( ( -LRB- cord-006870-f5w6fw6q 1839 36 22 22 CD cord-006870-f5w6fw6q 1839 37 - - SYM cord-006870-f5w6fw6q 1839 38 23 23 CD cord-006870-f5w6fw6q 1839 39 ) ) -RRB- cord-006870-f5w6fw6q 1839 40 respectively respectively RB cord-006870-f5w6fw6q 1839 41 . . . cord-006870-f5w6fw6q 1840 1 Early early JJ cord-006870-f5w6fw6q 1840 2 systematic systematic JJ cord-006870-f5w6fw6q 1840 3 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 1840 4 improves improve VBZ cord-006870-f5w6fw6q 1840 5 outcome outcome NN cord-006870-f5w6fw6q 1840 6 ( ( -LRB- cord-006870-f5w6fw6q 1840 7 including include VBG cord-006870-f5w6fw6q 1840 8 mRS mrs PRP$ cord-006870-f5w6fw6q 1840 9 5 5 CD cord-006870-f5w6fw6q 1840 10 ) ) -RRB- cord-006870-f5w6fw6q 1840 11 for for IN cord-006870-f5w6fw6q 1840 12 every every DT cord-006870-f5w6fw6q 1840 13 2 2 CD cord-006870-f5w6fw6q 1840 14 - - SYM cord-006870-f5w6fw6q 1840 15 3 3 CD cord-006870-f5w6fw6q 1840 16 patients patient NNS cord-006870-f5w6fw6q 1840 17 treated treat VBN cord-006870-f5w6fw6q 1840 18 . . . cord-006870-f5w6fw6q 1841 1 Excluding exclude VBG cord-006870-f5w6fw6q 1841 2 patients patient NNS cord-006870-f5w6fw6q 1841 3 with with IN cord-006870-f5w6fw6q 1841 4 mRS mRS NNP cord-006870-f5w6fw6q 1841 5 5 5 CD cord-006870-f5w6fw6q 1841 6 , , , cord-006870-f5w6fw6q 1841 7 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 1841 8 improves improve VBZ cord-006870-f5w6fw6q 1841 9 outcome outcome NN cord-006870-f5w6fw6q 1841 10 for for IN cord-006870-f5w6fw6q 1841 11 every every DT cord-006870-f5w6fw6q 1841 12 4.4 4.4 CD cord-006870-f5w6fw6q 1841 13 patients patient NNS cord-006870-f5w6fw6q 1841 14 treated treat VBN cord-006870-f5w6fw6q 1841 15 . . . cord-006870-f5w6fw6q 1842 1 The the DT cord-006870-f5w6fw6q 1842 2 algorithmic algorithmic JJ cord-006870-f5w6fw6q 1842 3 range range NN cord-006870-f5w6fw6q 1842 4 provides provide VBZ cord-006870-f5w6fw6q 1842 5 bounds bound NNS cord-006870-f5w6fw6q 1842 6 to to IN cord-006870-f5w6fw6q 1842 7 the the DT cord-006870-f5w6fw6q 1842 8 data datum NNS cord-006870-f5w6fw6q 1842 9 , , , cord-006870-f5w6fw6q 1842 10 while while IN cord-006870-f5w6fw6q 1842 11 the the DT cord-006870-f5w6fw6q 1842 12 expert expert NN cord-006870-f5w6fw6q 1842 13 geometric geometric JJ cord-006870-f5w6fw6q 1842 14 mean mean NN cord-006870-f5w6fw6q 1842 15 provides provide VBZ cord-006870-f5w6fw6q 1842 16 the the DT cord-006870-f5w6fw6q 1842 17 most most RBS cord-006870-f5w6fw6q 1842 18 accurate accurate JJ cord-006870-f5w6fw6q 1842 19 point point NN cord-006870-f5w6fw6q 1842 20 estimate estimate NN cord-006870-f5w6fw6q 1842 21 . . . cord-006870-f5w6fw6q 1843 1 These these DT cord-006870-f5w6fw6q 1843 2 data datum NNS cord-006870-f5w6fw6q 1843 3 provide provide VBP cord-006870-f5w6fw6q 1843 4 a a DT cord-006870-f5w6fw6q 1843 5 powerful powerful JJ cord-006870-f5w6fw6q 1843 6 tool tool NN cord-006870-f5w6fw6q 1843 7 to to TO cord-006870-f5w6fw6q 1843 8 describe describe VB cord-006870-f5w6fw6q 1843 9 the the DT cord-006870-f5w6fw6q 1843 10 potential potential JJ cord-006870-f5w6fw6q 1843 11 treatment treatment NN cord-006870-f5w6fw6q 1843 12 outcomes outcome NNS cord-006870-f5w6fw6q 1843 13 to to IN cord-006870-f5w6fw6q 1843 14 families family NNS cord-006870-f5w6fw6q 1843 15 during during IN cord-006870-f5w6fw6q 1843 16 the the DT cord-006870-f5w6fw6q 1843 17 first first JJ cord-006870-f5w6fw6q 1843 18 day day NN cord-006870-f5w6fw6q 1843 19 following follow VBG cord-006870-f5w6fw6q 1843 20 a a DT cord-006870-f5w6fw6q 1843 21 malignant malignant JJ cord-006870-f5w6fw6q 1843 22 middle middle JJ cord-006870-f5w6fw6q 1843 23 cerebral cerebral JJ cord-006870-f5w6fw6q 1843 24 artery artery NN cord-006870-f5w6fw6q 1843 25 infarction infarction NN cord-006870-f5w6fw6q 1843 26 . . . cord-006870-f5w6fw6q 1844 1 Background Background NNP cord-006870-f5w6fw6q 1844 2 Cerebral cerebral JJ cord-006870-f5w6fw6q 1844 3 bypass bypass NN cord-006870-f5w6fw6q 1844 4 surgery surgery NN cord-006870-f5w6fw6q 1844 5 is be VBZ cord-006870-f5w6fw6q 1844 6 performed perform VBN cord-006870-f5w6fw6q 1844 7 to to TO cord-006870-f5w6fw6q 1844 8 restore restore VB cord-006870-f5w6fw6q 1844 9 , , , cord-006870-f5w6fw6q 1844 10 or or CC cord-006870-f5w6fw6q 1844 11 revascularize revascularize JJ cord-006870-f5w6fw6q 1844 12 blood blood NN cord-006870-f5w6fw6q 1844 13 flow flow NN cord-006870-f5w6fw6q 1844 14 to to IN cord-006870-f5w6fw6q 1844 15 the the DT cord-006870-f5w6fw6q 1844 16 brain brain NN cord-006870-f5w6fw6q 1844 17 . . . cord-006870-f5w6fw6q 1845 1 Previous previous JJ cord-006870-f5w6fw6q 1845 2 studies study NNS cord-006870-f5w6fw6q 1845 3 have have VBP cord-006870-f5w6fw6q 1845 4 not not RB cord-006870-f5w6fw6q 1845 5 shown show VBN cord-006870-f5w6fw6q 1845 6 whether whether IN cord-006870-f5w6fw6q 1845 7 emergency emergency NN cord-006870-f5w6fw6q 1845 8 surgical surgical JJ cord-006870-f5w6fw6q 1845 9 reperfusion reperfusion NN cord-006870-f5w6fw6q 1845 10 therapy therapy NN cord-006870-f5w6fw6q 1845 11 may may MD cord-006870-f5w6fw6q 1845 12 be be VB cord-006870-f5w6fw6q 1845 13 effective effective JJ cord-006870-f5w6fw6q 1845 14 in in IN cord-006870-f5w6fw6q 1845 15 acute acute JJ cord-006870-f5w6fw6q 1845 16 ischemic ischemic JJ cord-006870-f5w6fw6q 1845 17 stroke stroke NN cord-006870-f5w6fw6q 1845 18 patients patient NNS cord-006870-f5w6fw6q 1845 19 with with IN cord-006870-f5w6fw6q 1845 20 large large JJ cord-006870-f5w6fw6q 1845 21 artery artery NN cord-006870-f5w6fw6q 1845 22 occlusion occlusion NN cord-006870-f5w6fw6q 1845 23 and and CC cord-006870-f5w6fw6q 1845 24 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 1845 25 deterioration deterioration NN cord-006870-f5w6fw6q 1845 26 . . . cord-006870-f5w6fw6q 1846 1 Objective objective JJ cord-006870-f5w6fw6q 1847 1 To to TO cord-006870-f5w6fw6q 1847 2 evaluate evaluate VB cord-006870-f5w6fw6q 1847 3 the the DT cord-006870-f5w6fw6q 1847 4 effect effect NN cord-006870-f5w6fw6q 1847 5 of of IN cord-006870-f5w6fw6q 1847 6 emergency emergency NN cord-006870-f5w6fw6q 1847 7 STA STA NNP cord-006870-f5w6fw6q 1847 8 - - HYPH cord-006870-f5w6fw6q 1847 9 MCA MCA NNP cord-006870-f5w6fw6q 1847 10 bypass bypass NN cord-006870-f5w6fw6q 1847 11 surgery surgery NN cord-006870-f5w6fw6q 1847 12 on on IN cord-006870-f5w6fw6q 1847 13 the the DT cord-006870-f5w6fw6q 1847 14 outcome outcome NN cord-006870-f5w6fw6q 1847 15 of of IN cord-006870-f5w6fw6q 1847 16 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 1847 17 compromised compromised JJ cord-006870-f5w6fw6q 1847 18 patients patient NNS cord-006870-f5w6fw6q 1847 19 who who WP cord-006870-f5w6fw6q 1847 20 had have VBD cord-006870-f5w6fw6q 1847 21 progressive progressive JJ cord-006870-f5w6fw6q 1847 22 or or CC cord-006870-f5w6fw6q 1847 23 fluctuating fluctuating JJ cord-006870-f5w6fw6q 1847 24 stroke stroke NN cord-006870-f5w6fw6q 1847 25 despite despite IN cord-006870-f5w6fw6q 1847 26 best good JJS cord-006870-f5w6fw6q 1847 27 medical medical JJ cord-006870-f5w6fw6q 1847 28 treatments treatment NNS cord-006870-f5w6fw6q 1847 29 . . . cord-006870-f5w6fw6q 1848 1 We -PRON- PRP cord-006870-f5w6fw6q 1848 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 1848 3 reviewed review VBD cord-006870-f5w6fw6q 1848 4 the the DT cord-006870-f5w6fw6q 1848 5 clinical clinical JJ cord-006870-f5w6fw6q 1848 6 and and CC cord-006870-f5w6fw6q 1848 7 radiological radiological JJ cord-006870-f5w6fw6q 1848 8 data datum NNS cord-006870-f5w6fw6q 1848 9 of of IN cord-006870-f5w6fw6q 1848 10 57 57 CD cord-006870-f5w6fw6q 1848 11 consecutive consecutive JJ cord-006870-f5w6fw6q 1848 12 patients patient NNS cord-006870-f5w6fw6q 1848 13 treated treat VBN cord-006870-f5w6fw6q 1848 14 by by IN cord-006870-f5w6fw6q 1848 15 both both DT cord-006870-f5w6fw6q 1848 16 emergency emergency NN cord-006870-f5w6fw6q 1848 17 bypass bypass NN cord-006870-f5w6fw6q 1848 18 surgery surgery NN cord-006870-f5w6fw6q 1848 19 ( ( -LRB- cord-006870-f5w6fw6q 1848 20 31 31 CD cord-006870-f5w6fw6q 1848 21 cases case NNS cord-006870-f5w6fw6q 1848 22 , , , cord-006870-f5w6fw6q 1848 23 54.4 54.4 CD cord-006870-f5w6fw6q 1848 24 % % NN cord-006870-f5w6fw6q 1848 25 ) ) -RRB- cord-006870-f5w6fw6q 1848 26 and and CC cord-006870-f5w6fw6q 1848 27 elective elective JJ cord-006870-f5w6fw6q 1848 28 bypass bypass NN cord-006870-f5w6fw6q 1848 29 surgery surgery NN cord-006870-f5w6fw6q 1848 30 ( ( -LRB- cord-006870-f5w6fw6q 1848 31 26 26 CD cord-006870-f5w6fw6q 1848 32 cases case NNS cord-006870-f5w6fw6q 1848 33 , , , cord-006870-f5w6fw6q 1848 34 45.6 45.6 CD cord-006870-f5w6fw6q 1848 35 % % NN cord-006870-f5w6fw6q 1848 36 ) ) -RRB- cord-006870-f5w6fw6q 1848 37 due due IN cord-006870-f5w6fw6q 1848 38 to to IN cord-006870-f5w6fw6q 1848 39 large large JJ cord-006870-f5w6fw6q 1848 40 artery artery NN cord-006870-f5w6fw6q 1848 41 occlusion occlusion NN cord-006870-f5w6fw6q 1848 42 at at IN cord-006870-f5w6fw6q 1848 43 a a DT cord-006870-f5w6fw6q 1848 44 single single JJ cord-006870-f5w6fw6q 1848 45 center center NN cord-006870-f5w6fw6q 1848 46 . . . cord-006870-f5w6fw6q 1849 1 The the DT cord-006870-f5w6fw6q 1849 2 effect effect NN cord-006870-f5w6fw6q 1849 3 of of IN cord-006870-f5w6fw6q 1849 4 surgical surgical JJ cord-006870-f5w6fw6q 1849 5 therapy therapy NN cord-006870-f5w6fw6q 1849 6 was be VBD cord-006870-f5w6fw6q 1849 7 measured measure VBN cord-006870-f5w6fw6q 1849 8 with with IN cord-006870-f5w6fw6q 1849 9 the the DT cord-006870-f5w6fw6q 1849 10 modified modify VBN cord-006870-f5w6fw6q 1849 11 Rankin Rankin NNP cord-006870-f5w6fw6q 1849 12 scale scale NN cord-006870-f5w6fw6q 1849 13 ( ( -LRB- cord-006870-f5w6fw6q 1849 14 mRS mrs UH cord-006870-f5w6fw6q 1849 15 ) ) -RRB- cord-006870-f5w6fw6q 1849 16 at at IN cord-006870-f5w6fw6q 1849 17 3 3 CD cord-006870-f5w6fw6q 1849 18 months month NNS cord-006870-f5w6fw6q 1849 19 . . . cord-006870-f5w6fw6q 1850 1 Clinical clinical JJ cord-006870-f5w6fw6q 1850 2 severity severity NN cord-006870-f5w6fw6q 1850 3 was be VBD cord-006870-f5w6fw6q 1850 4 evaluated evaluate VBN cord-006870-f5w6fw6q 1850 5 by by IN cord-006870-f5w6fw6q 1850 6 the the DT cord-006870-f5w6fw6q 1850 7 National National NNP cord-006870-f5w6fw6q 1850 8 Institutes Institutes NNPS cord-006870-f5w6fw6q 1850 9 of of IN cord-006870-f5w6fw6q 1850 10 Health Health NNP cord-006870-f5w6fw6q 1850 11 Stroke Stroke NNP cord-006870-f5w6fw6q 1850 12 Scale Scale NNP cord-006870-f5w6fw6q 1850 13 ( ( -LRB- cord-006870-f5w6fw6q 1850 14 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1850 15 ) ) -RRB- cord-006870-f5w6fw6q 1850 16 between between IN cord-006870-f5w6fw6q 1850 17 pre pre JJ cord-006870-f5w6fw6q 1850 18 - - JJ cord-006870-f5w6fw6q 1850 19 and and CC cord-006870-f5w6fw6q 1850 20 post post JJ cord-006870-f5w6fw6q 1850 21 - - JJ cord-006870-f5w6fw6q 1850 22 operative operative JJ cord-006870-f5w6fw6q 1850 23 state state NN cord-006870-f5w6fw6q 1850 24 . . . cord-006870-f5w6fw6q 1851 1 Major major JJ cord-006870-f5w6fw6q 1851 2 perioperative perioperative JJ cord-006870-f5w6fw6q 1851 3 complications complication NNS cord-006870-f5w6fw6q 1851 4 were be VBD cord-006870-f5w6fw6q 1851 5 defined define VBN cord-006870-f5w6fw6q 1851 6 as as IN cord-006870-f5w6fw6q 1851 7 any any DT cord-006870-f5w6fw6q 1851 8 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1851 9 stroke stroke NN cord-006870-f5w6fw6q 1851 10 , , , cord-006870-f5w6fw6q 1851 11 myocardial myocardial JJ cord-006870-f5w6fw6q 1851 12 infarction infarction NN cord-006870-f5w6fw6q 1851 13 and and CC cord-006870-f5w6fw6q 1851 14 death death NN cord-006870-f5w6fw6q 1851 15 . . . cord-006870-f5w6fw6q 1852 1 Results result NNS cord-006870-f5w6fw6q 1853 1 Occlusive occlusive NN cord-006870-f5w6fw6q 1853 2 sites site NNS cord-006870-f5w6fw6q 1853 3 were be VBD cord-006870-f5w6fw6q 1853 4 the the DT cord-006870-f5w6fw6q 1853 5 cervical cervical JJ cord-006870-f5w6fw6q 1853 6 internal internal JJ cord-006870-f5w6fw6q 1853 7 carotid carotid JJ cord-006870-f5w6fw6q 1853 8 artery artery NN cord-006870-f5w6fw6q 1853 9 in in IN cord-006870-f5w6fw6q 1853 10 32 32 CD cord-006870-f5w6fw6q 1853 11 ( ( -LRB- cord-006870-f5w6fw6q 1853 12 56.1 56.1 CD cord-006870-f5w6fw6q 1853 13 % % NN cord-006870-f5w6fw6q 1853 14 ) ) -RRB- cord-006870-f5w6fw6q 1853 15 patients patient NNS cord-006870-f5w6fw6q 1853 16 and and CC cord-006870-f5w6fw6q 1853 17 the the DT cord-006870-f5w6fw6q 1853 18 middle middle JJ cord-006870-f5w6fw6q 1853 19 patients patient NNS cord-006870-f5w6fw6q 1853 20 in in IN cord-006870-f5w6fw6q 1853 21 emergency emergency NN cord-006870-f5w6fw6q 1853 22 surgery surgery NN cord-006870-f5w6fw6q 1853 23 group group NN cord-006870-f5w6fw6q 1853 24 and and CC cord-006870-f5w6fw6q 1853 25 24 24 CD cord-006870-f5w6fw6q 1853 26 ( ( -LRB- cord-006870-f5w6fw6q 1853 27 92.3 92.3 CD cord-006870-f5w6fw6q 1853 28 % % NN cord-006870-f5w6fw6q 1853 29 ) ) -RRB- cord-006870-f5w6fw6q 1853 30 patients patient NNS cord-006870-f5w6fw6q 1853 31 in in IN cord-006870-f5w6fw6q 1853 32 elective elective JJ cord-006870-f5w6fw6q 1853 33 surgery surgery NN cord-006870-f5w6fw6q 1853 34 group group NN cord-006870-f5w6fw6q 1853 35 . . . cord-006870-f5w6fw6q 1854 1 Emergency emergency NN cord-006870-f5w6fw6q 1854 2 bypass bypass NN cord-006870-f5w6fw6q 1854 3 surgery surgery NN cord-006870-f5w6fw6q 1854 4 improved improve VBD cord-006870-f5w6fw6q 1854 5 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1854 6 ( ( -LRB- cord-006870-f5w6fw6q 1854 7 preoperatively preoperatively NNP cord-006870-f5w6fw6q 1854 8 , , , cord-006870-f5w6fw6q 1854 9 9 9 CD cord-006870-f5w6fw6q 1854 10 [ [ -LRB- cord-006870-f5w6fw6q 1854 11 4 4 CD cord-006870-f5w6fw6q 1854 12 - - SYM cord-006870-f5w6fw6q 1854 13 16 16 CD cord-006870-f5w6fw6q 1854 14 ] ] -RRB- cord-006870-f5w6fw6q 1854 15 ; ; : cord-006870-f5w6fw6q 1854 16 2 2 CD cord-006870-f5w6fw6q 1854 17 weeks week NNS cord-006870-f5w6fw6q 1854 18 postoperatively postoperatively RB cord-006870-f5w6fw6q 1854 19 , , , cord-006870-f5w6fw6q 1854 20 6 6 CD cord-006870-f5w6fw6q 1854 21 [ [ -LRB- cord-006870-f5w6fw6q 1854 22 2 2 CD cord-006870-f5w6fw6q 1854 23 - - SYM cord-006870-f5w6fw6q 1854 24 11 11 CD cord-006870-f5w6fw6q 1854 25 ] ] -RRB- cord-006870-f5w6fw6q 1854 26 ) ) -RRB- cord-006870-f5w6fw6q 1854 27 . . . cord-006870-f5w6fw6q 1855 1 Major major JJ cord-006870-f5w6fw6q 1855 2 perioperative perioperative JJ cord-006870-f5w6fw6q 1855 3 complications complication NNS cord-006870-f5w6fw6q 1855 4 in in IN cord-006870-f5w6fw6q 1855 5 30 30 CD cord-006870-f5w6fw6q 1855 6 days day NNS cord-006870-f5w6fw6q 1855 7 were be VBD cord-006870-f5w6fw6q 1855 8 happened happen VBN cord-006870-f5w6fw6q 1855 9 in in IN cord-006870-f5w6fw6q 1855 10 three three CD cord-006870-f5w6fw6q 1855 11 patients patient NNS cord-006870-f5w6fw6q 1855 12 ( ( -LRB- cord-006870-f5w6fw6q 1855 13 9.7 9.7 CD cord-006870-f5w6fw6q 1855 14 % % NN cord-006870-f5w6fw6q 1855 15 ) ) -RRB- cord-006870-f5w6fw6q 1855 16 after after IN cord-006870-f5w6fw6q 1855 17 emergency emergency NN cord-006870-f5w6fw6q 1855 18 bypass bypass NN cord-006870-f5w6fw6q 1855 19 surgery surgery NN cord-006870-f5w6fw6q 1855 20 , , , cord-006870-f5w6fw6q 1855 21 and and CC cord-006870-f5w6fw6q 1855 22 four four CD cord-006870-f5w6fw6q 1855 23 patients patient NNS cord-006870-f5w6fw6q 1855 24 ( ( -LRB- cord-006870-f5w6fw6q 1855 25 15.4 15.4 CD cord-006870-f5w6fw6q 1855 26 % % NN cord-006870-f5w6fw6q 1855 27 ) ) -RRB- cord-006870-f5w6fw6q 1855 28 after after IN cord-006870-f5w6fw6q 1855 29 elective elective JJ cord-006870-f5w6fw6q 1855 30 bypass bypass NN cord-006870-f5w6fw6q 1855 31 surgery surgery NN cord-006870-f5w6fw6q 1855 32 . . . cord-006870-f5w6fw6q 1856 1 Emergency emergency NN cord-006870-f5w6fw6q 1856 2 revascularization revascularization NN cord-006870-f5w6fw6q 1856 3 surgery surgery NN cord-006870-f5w6fw6q 1856 4 may may MD cord-006870-f5w6fw6q 1856 5 be be VB cord-006870-f5w6fw6q 1856 6 effective effective JJ cord-006870-f5w6fw6q 1856 7 alternative alternative JJ cord-006870-f5w6fw6q 1856 8 treatment treatment NN cord-006870-f5w6fw6q 1856 9 for for IN cord-006870-f5w6fw6q 1856 10 acute acute JJ cord-006870-f5w6fw6q 1856 11 ischemic ischemic JJ cord-006870-f5w6fw6q 1856 12 stroke stroke NN cord-006870-f5w6fw6q 1856 13 patients patient NNS cord-006870-f5w6fw6q 1856 14 with with IN cord-006870-f5w6fw6q 1856 15 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 1856 16 deterioration deterioration NN cord-006870-f5w6fw6q 1856 17 refractory refractory JJ cord-006870-f5w6fw6q 1856 18 to to IN cord-006870-f5w6fw6q 1856 19 maximal maximal JJ cord-006870-f5w6fw6q 1856 20 medical medical JJ cord-006870-f5w6fw6q 1856 21 treatments treatment NNS cord-006870-f5w6fw6q 1856 22 without without IN cord-006870-f5w6fw6q 1856 23 significant significant JJ cord-006870-f5w6fw6q 1856 24 complications complication NNS cord-006870-f5w6fw6q 1856 25 . . . cord-006870-f5w6fw6q 1857 1 Larger large JJR cord-006870-f5w6fw6q 1857 2 randomized randomized JJ cord-006870-f5w6fw6q 1857 3 clinical clinical JJ cord-006870-f5w6fw6q 1857 4 study study NN cord-006870-f5w6fw6q 1857 5 is be VBZ cord-006870-f5w6fw6q 1857 6 needed need VBN cord-006870-f5w6fw6q 1857 7 to to TO cord-006870-f5w6fw6q 1857 8 evaluate evaluate VB cord-006870-f5w6fw6q 1857 9 the the DT cord-006870-f5w6fw6q 1857 10 effect effect NN cord-006870-f5w6fw6q 1857 11 of of IN cord-006870-f5w6fw6q 1857 12 emergency emergency NN cord-006870-f5w6fw6q 1857 13 revascularization revascularization NN cord-006870-f5w6fw6q 1857 14 surgery surgery NN cord-006870-f5w6fw6q 1857 15 in in IN cord-006870-f5w6fw6q 1857 16 acute acute JJ cord-006870-f5w6fw6q 1857 17 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 1857 18 deterioration deterioration NN cord-006870-f5w6fw6q 1857 19 . . . cord-006870-f5w6fw6q 1858 1 Multiple multiple JJ cord-006870-f5w6fw6q 1858 2 studies study NNS cord-006870-f5w6fw6q 1858 3 have have VBP cord-006870-f5w6fw6q 1858 4 reported report VBN cord-006870-f5w6fw6q 1858 5 lower low JJR cord-006870-f5w6fw6q 1858 6 mortality mortality NN cord-006870-f5w6fw6q 1858 7 rates rate NNS cord-006870-f5w6fw6q 1858 8 in in IN cord-006870-f5w6fw6q 1858 9 obese obese JJ cord-006870-f5w6fw6q 1858 10 patients patient NNS cord-006870-f5w6fw6q 1858 11 with with IN cord-006870-f5w6fw6q 1858 12 various various JJ cord-006870-f5w6fw6q 1858 13 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 1858 14 disorders disorder NNS cord-006870-f5w6fw6q 1858 15 , , , cord-006870-f5w6fw6q 1858 16 a a DT cord-006870-f5w6fw6q 1858 17 phenomenon phenomenon NN cord-006870-f5w6fw6q 1858 18 called call VBN cord-006870-f5w6fw6q 1858 19 as as IN cord-006870-f5w6fw6q 1858 20 the the DT cord-006870-f5w6fw6q 1858 21 ' ' `` cord-006870-f5w6fw6q 1858 22 obesity obesity NN cord-006870-f5w6fw6q 1858 23 paradox paradox NN cord-006870-f5w6fw6q 1858 24 ' ' '' cord-006870-f5w6fw6q 1858 25 . . . cord-006870-f5w6fw6q 1859 1 Such such JJ cord-006870-f5w6fw6q 1859 2 relationship relationship NN cord-006870-f5w6fw6q 1859 3 has have VBZ cord-006870-f5w6fw6q 1859 4 been be VBN cord-006870-f5w6fw6q 1859 5 largely largely RB cord-006870-f5w6fw6q 1859 6 unreported unreported JJ cord-006870-f5w6fw6q 1859 7 in in IN cord-006870-f5w6fw6q 1859 8 patients patient NNS cord-006870-f5w6fw6q 1859 9 with with IN cord-006870-f5w6fw6q 1859 10 neurological neurological JJ cord-006870-f5w6fw6q 1859 11 pathologies pathology NNS cord-006870-f5w6fw6q 1859 12 especially especially RB cord-006870-f5w6fw6q 1859 13 stroke stroke VBP cord-006870-f5w6fw6q 1859 14 . . . cord-006870-f5w6fw6q 1860 1 This this DT cord-006870-f5w6fw6q 1860 2 study study NN cord-006870-f5w6fw6q 1860 3 reports report VBZ cord-006870-f5w6fw6q 1860 4 the the DT cord-006870-f5w6fw6q 1860 5 effect effect NN cord-006870-f5w6fw6q 1860 6 of of IN cord-006870-f5w6fw6q 1860 7 obesity obesity NN cord-006870-f5w6fw6q 1860 8 on on IN cord-006870-f5w6fw6q 1860 9 prognosis prognosis NN cord-006870-f5w6fw6q 1860 10 in in IN cord-006870-f5w6fw6q 1860 11 patients patient NNS cord-006870-f5w6fw6q 1860 12 with with IN cord-006870-f5w6fw6q 1860 13 ischemic ischemic JJ cord-006870-f5w6fw6q 1860 14 stroke stroke NN cord-006870-f5w6fw6q 1860 15 . . . cord-006870-f5w6fw6q 1861 1 Analysis Analysis NNP cord-006870-f5w6fw6q 1861 2 of of IN cord-006870-f5w6fw6q 1861 3 National National NNP cord-006870-f5w6fw6q 1861 4 Inpatient Inpatient NNP cord-006870-f5w6fw6q 1861 5 Sample Sample NNP cord-006870-f5w6fw6q 1861 6 data datum NNS cord-006870-f5w6fw6q 1861 7 ( ( -LRB- cord-006870-f5w6fw6q 1861 8 2003 2003 CD cord-006870-f5w6fw6q 1861 9 - - SYM cord-006870-f5w6fw6q 1861 10 2013 2013 CD cord-006870-f5w6fw6q 1861 11 ) ) -RRB- cord-006870-f5w6fw6q 1861 12 showed show VBD cord-006870-f5w6fw6q 1861 13 a a DT cord-006870-f5w6fw6q 1861 14 total total NN cord-006870-f5w6fw6q 1861 15 of of IN cord-006870-f5w6fw6q 1861 16 1,168,847 1,168,847 CD cord-006870-f5w6fw6q 1861 17 patients patient NNS cord-006870-f5w6fw6q 1861 18 discharged discharge VBN cord-006870-f5w6fw6q 1861 19 with with IN cord-006870-f5w6fw6q 1861 20 primary primary JJ cord-006870-f5w6fw6q 1861 21 diagnosis diagnosis NN cord-006870-f5w6fw6q 1861 22 of of IN cord-006870-f5w6fw6q 1861 23 IS IS NNP cord-006870-f5w6fw6q 1861 24 , , , cord-006870-f5w6fw6q 1861 25 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 1861 26 Code Code NNP cord-006870-f5w6fw6q 1861 27 433.xx 433.xx CD cord-006870-f5w6fw6q 1861 28 and and CC cord-006870-f5w6fw6q 1861 29 434.xx 434.xx CD cord-006870-f5w6fw6q 1861 30 . . . cord-006870-f5w6fw6q 1862 1 Patients patient NNS cord-006870-f5w6fw6q 1862 2 with with IN cord-006870-f5w6fw6q 1862 3 obesity obesity NN cord-006870-f5w6fw6q 1862 4 were be VBD cord-006870-f5w6fw6q 1862 5 identified identify VBN cord-006870-f5w6fw6q 1862 6 using use VBG cord-006870-f5w6fw6q 1862 7 Agency Agency NNP cord-006870-f5w6fw6q 1862 8 of of IN cord-006870-f5w6fw6q 1862 9 Healthcare Healthcare NNP cord-006870-f5w6fw6q 1862 10 Research Research NNP cord-006870-f5w6fw6q 1862 11 and and CC cord-006870-f5w6fw6q 1862 12 Quality Quality NNP cord-006870-f5w6fw6q 1862 13 ( ( -LRB- cord-006870-f5w6fw6q 1862 14 AHRQ AHRQ NNP cord-006870-f5w6fw6q 1862 15 ) ) -RRB- cord-006870-f5w6fw6q 1862 16 criteria criterion NNS cord-006870-f5w6fw6q 1862 17 . . . cord-006870-f5w6fw6q 1863 1 We -PRON- PRP cord-006870-f5w6fw6q 1863 2 used use VBD cord-006870-f5w6fw6q 1863 3 binary binary JJ cord-006870-f5w6fw6q 1863 4 regression regression NN cord-006870-f5w6fw6q 1863 5 to to TO cord-006870-f5w6fw6q 1863 6 compare compare VB cord-006870-f5w6fw6q 1863 7 inhospital inhospital JJ cord-006870-f5w6fw6q 1863 8 mortality mortality NN cord-006870-f5w6fw6q 1863 9 between between IN cord-006870-f5w6fw6q 1863 10 obese obese JJ cord-006870-f5w6fw6q 1863 11 and and CC cord-006870-f5w6fw6q 1863 12 non non JJ cord-006870-f5w6fw6q 1863 13 - - JJ cord-006870-f5w6fw6q 1863 14 obese obese JJ cord-006870-f5w6fw6q 1863 15 patients patient NNS cord-006870-f5w6fw6q 1863 16 with with IN cord-006870-f5w6fw6q 1863 17 ischemic ischemic JJ cord-006870-f5w6fw6q 1863 18 stroke stroke NN cord-006870-f5w6fw6q 1863 19 . . . cord-006870-f5w6fw6q 1864 1 From from IN cord-006870-f5w6fw6q 1864 2 2003 2003 CD cord-006870-f5w6fw6q 1864 3 - - SYM cord-006870-f5w6fw6q 1864 4 2013 2013 CD cord-006870-f5w6fw6q 1864 5 , , , cord-006870-f5w6fw6q 1864 6 1,168,847 1,168,847 CD cord-006870-f5w6fw6q 1864 7 patients patient NNS cord-006870-f5w6fw6q 1864 8 with with IN cord-006870-f5w6fw6q 1864 9 ischemic ischemic JJ cord-006870-f5w6fw6q 1864 10 stroke stroke NN cord-006870-f5w6fw6q 1864 11 were be VBD cord-006870-f5w6fw6q 1864 12 identified identify VBN cord-006870-f5w6fw6q 1864 13 of of IN cord-006870-f5w6fw6q 1864 14 which which WDT cord-006870-f5w6fw6q 1864 15 8.7 8.7 CD cord-006870-f5w6fw6q 1864 16 % % NN cord-006870-f5w6fw6q 1864 17 were be VBD cord-006870-f5w6fw6q 1864 18 found find VBN cord-006870-f5w6fw6q 1864 19 to to TO cord-006870-f5w6fw6q 1864 20 be be VB cord-006870-f5w6fw6q 1864 21 obese obese JJ cord-006870-f5w6fw6q 1864 22 . . . cord-006870-f5w6fw6q 1865 1 Obese obese JJ cord-006870-f5w6fw6q 1865 2 patients patient NNS cord-006870-f5w6fw6q 1865 3 with with IN cord-006870-f5w6fw6q 1865 4 ischemic ischemic JJ cord-006870-f5w6fw6q 1865 5 stroke stroke NN cord-006870-f5w6fw6q 1865 6 were be VBD cord-006870-f5w6fw6q 1865 7 more more RBR cord-006870-f5w6fw6q 1865 8 often often RB cord-006870-f5w6fw6q 1865 9 younger young JJR cord-006870-f5w6fw6q 1865 10 , , , cord-006870-f5w6fw6q 1865 11 female female JJ cord-006870-f5w6fw6q 1865 12 , , , cord-006870-f5w6fw6q 1865 13 and and CC cord-006870-f5w6fw6q 1865 14 African african JJ cord-006870-f5w6fw6q 1865 15 American American NNP cord-006870-f5w6fw6q 1865 16 as as IN cord-006870-f5w6fw6q 1865 17 compared compare VBN cord-006870-f5w6fw6q 1865 18 to to IN cord-006870-f5w6fw6q 1865 19 Caucasian Caucasian NNP cord-006870-f5w6fw6q 1865 20 . . . cord-006870-f5w6fw6q 1866 1 After after IN cord-006870-f5w6fw6q 1866 2 risk risk NN cord-006870-f5w6fw6q 1866 3 adjustment adjustment NN cord-006870-f5w6fw6q 1866 4 for for IN cord-006870-f5w6fw6q 1866 5 demographics demographic NNS cord-006870-f5w6fw6q 1866 6 , , , cord-006870-f5w6fw6q 1866 7 and and CC cord-006870-f5w6fw6q 1866 8 baseline baseline JJ cord-006870-f5w6fw6q 1866 9 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 1866 10 , , , cord-006870-f5w6fw6q 1866 11 obese obese JJ cord-006870-f5w6fw6q 1866 12 patients patient NNS cord-006870-f5w6fw6q 1866 13 with with IN cord-006870-f5w6fw6q 1866 14 ischemic ischemic JJ cord-006870-f5w6fw6q 1866 15 stroke stroke NN cord-006870-f5w6fw6q 1866 16 had have VBD cord-006870-f5w6fw6q 1866 17 lower low JJR cord-006870-f5w6fw6q 1866 18 observed observe VBN cord-006870-f5w6fw6q 1866 19 in in IN cord-006870-f5w6fw6q 1866 20 hospital hospital NN cord-006870-f5w6fw6q 1866 21 mortality mortality NN cord-006870-f5w6fw6q 1866 22 as as IN cord-006870-f5w6fw6q 1866 23 compared compare VBN cord-006870-f5w6fw6q 1866 24 with with IN cord-006870-f5w6fw6q 1866 25 non non JJ cord-006870-f5w6fw6q 1866 26 - - JJ cord-006870-f5w6fw6q 1866 27 obese obese JJ cord-006870-f5w6fw6q 1866 28 patients patient NNS cord-006870-f5w6fw6q 1866 29 with with IN cord-006870-f5w6fw6q 1866 30 ischemic ischemic JJ cord-006870-f5w6fw6q 1866 31 stroke stroke NN cord-006870-f5w6fw6q 1866 32 ( ( -LRB- cord-006870-f5w6fw6q 1866 33 2.5 2.5 CD cord-006870-f5w6fw6q 1866 34 % % NN cord-006870-f5w6fw6q 1866 35 vs vs IN cord-006870-f5w6fw6q 1866 36 4 4 CD cord-006870-f5w6fw6q 1866 37 % % NN cord-006870-f5w6fw6q 1866 38 , , , cord-006870-f5w6fw6q 1866 39 OR or CC cord-006870-f5w6fw6q 1866 40 : : : cord-006870-f5w6fw6q 1866 41 0.717 0.717 CD cord-006870-f5w6fw6q 1866 42 CI=0.681 CI=0.681 VBN cord-006870-f5w6fw6q 1866 43 - - HYPH cord-006870-f5w6fw6q 1866 44 0.756 0.756 CD cord-006870-f5w6fw6q 1866 45 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 1866 46 ) ) -RRB- cord-006870-f5w6fw6q 1866 47 . . . cord-006870-f5w6fw6q 1867 1 From from IN cord-006870-f5w6fw6q 1867 2 an an DT cord-006870-f5w6fw6q 1867 3 eleven eleven CD cord-006870-f5w6fw6q 1867 4 year year NN cord-006870-f5w6fw6q 1867 5 nationwide nationwide JJ cord-006870-f5w6fw6q 1867 6 cohort cohort NN cord-006870-f5w6fw6q 1867 7 of of IN cord-006870-f5w6fw6q 1867 8 patients patient NNS cord-006870-f5w6fw6q 1867 9 with with IN cord-006870-f5w6fw6q 1867 10 ischemic ischemic JJ cord-006870-f5w6fw6q 1867 11 strokes stroke NNS cord-006870-f5w6fw6q 1867 12 , , , cord-006870-f5w6fw6q 1867 13 we -PRON- PRP cord-006870-f5w6fw6q 1867 14 observed observe VBD cord-006870-f5w6fw6q 1867 15 a a DT cord-006870-f5w6fw6q 1867 16 significant significant JJ cord-006870-f5w6fw6q 1867 17 protective protective JJ cord-006870-f5w6fw6q 1867 18 effect effect NN cord-006870-f5w6fw6q 1867 19 of of IN cord-006870-f5w6fw6q 1867 20 obesity obesity NN cord-006870-f5w6fw6q 1867 21 and and CC cord-006870-f5w6fw6q 1867 22 better well JJR cord-006870-f5w6fw6q 1867 23 prognosis prognosis NN cord-006870-f5w6fw6q 1867 24 including include VBG cord-006870-f5w6fw6q 1867 25 a a DT cord-006870-f5w6fw6q 1867 26 lower low JJR cord-006870-f5w6fw6q 1867 27 mortality mortality NN cord-006870-f5w6fw6q 1867 28 rate rate NN cord-006870-f5w6fw6q 1867 29 . . . cord-006870-f5w6fw6q 1868 1 More More JJR cord-006870-f5w6fw6q 1868 2 prospective prospective JJ cord-006870-f5w6fw6q 1868 3 studies study NNS cord-006870-f5w6fw6q 1868 4 are be VBP cord-006870-f5w6fw6q 1868 5 warranted warrant VBN cord-006870-f5w6fw6q 1868 6 to to TO cord-006870-f5w6fw6q 1868 7 further further RB cord-006870-f5w6fw6q 1868 8 analyze analyze VB cord-006870-f5w6fw6q 1868 9 this this DT cord-006870-f5w6fw6q 1868 10 counter counter JJ cord-006870-f5w6fw6q 1868 11 - - JJ cord-006870-f5w6fw6q 1868 12 intuitive intuitive JJ cord-006870-f5w6fw6q 1868 13 trend trend NN cord-006870-f5w6fw6q 1868 14 . . . cord-006870-f5w6fw6q 1869 1 Very very RB cord-006870-f5w6fw6q 1869 2 early early JJ cord-006870-f5w6fw6q 1869 3 mobilization mobilization NN cord-006870-f5w6fw6q 1869 4 of of IN cord-006870-f5w6fw6q 1869 5 critical critical JJ cord-006870-f5w6fw6q 1869 6 care care NN cord-006870-f5w6fw6q 1869 7 patients patient NNS cord-006870-f5w6fw6q 1869 8 improves improve VBZ cord-006870-f5w6fw6q 1869 9 outcome outcome NN cord-006870-f5w6fw6q 1869 10 , , , cord-006870-f5w6fw6q 1869 11 length length NN cord-006870-f5w6fw6q 1869 12 of of IN cord-006870-f5w6fw6q 1869 13 stay stay NN cord-006870-f5w6fw6q 1869 14 , , , cord-006870-f5w6fw6q 1869 15 and and CC cord-006870-f5w6fw6q 1869 16 patient patient JJ cord-006870-f5w6fw6q 1869 17 satisfaction satisfaction NN cord-006870-f5w6fw6q 1869 18 . . . cord-006870-f5w6fw6q 1870 1 Data datum NNS cord-006870-f5w6fw6q 1870 2 for for IN cord-006870-f5w6fw6q 1870 3 efficacy efficacy NN cord-006870-f5w6fw6q 1870 4 of of IN cord-006870-f5w6fw6q 1870 5 very very RB cord-006870-f5w6fw6q 1870 6 early early JJ cord-006870-f5w6fw6q 1870 7 mobilization mobilization NN cord-006870-f5w6fw6q 1870 8 for for IN cord-006870-f5w6fw6q 1870 9 stroke stroke NN cord-006870-f5w6fw6q 1870 10 patients patient NNS cord-006870-f5w6fw6q 1870 11 have have VBP cord-006870-f5w6fw6q 1870 12 been be VBN cord-006870-f5w6fw6q 1870 13 mixed mix VBN cord-006870-f5w6fw6q 1870 14 , , , cord-006870-f5w6fw6q 1870 15 and and CC cord-006870-f5w6fw6q 1870 16 there there EX cord-006870-f5w6fw6q 1870 17 is be VBZ cord-006870-f5w6fw6q 1870 18 limited limited JJ cord-006870-f5w6fw6q 1870 19 outcomes outcome NNS cord-006870-f5w6fw6q 1870 20 data datum NNS cord-006870-f5w6fw6q 1870 21 for for IN cord-006870-f5w6fw6q 1870 22 patients patient NNS cord-006870-f5w6fw6q 1870 23 mobilized mobilize VBN cord-006870-f5w6fw6q 1870 24 within within IN cord-006870-f5w6fw6q 1870 25 24 24 CD cord-006870-f5w6fw6q 1870 26 hours hour NNS cord-006870-f5w6fw6q 1870 27 of of IN cord-006870-f5w6fw6q 1870 28 receiving receive VBG cord-006870-f5w6fw6q 1870 29 intravenous intravenous JJ cord-006870-f5w6fw6q 1870 30 alteplase alteplase NN cord-006870-f5w6fw6q 1870 31 ( ( -LRB- cord-006870-f5w6fw6q 1870 32 IV IV NNP cord-006870-f5w6fw6q 1870 33 tPA tPA NNP cord-006870-f5w6fw6q 1870 34 ) ) -RRB- cord-006870-f5w6fw6q 1870 35 . . . cord-006870-f5w6fw6q 1871 1 The the DT cord-006870-f5w6fw6q 1871 2 objective objective NN cord-006870-f5w6fw6q 1871 3 of of IN cord-006870-f5w6fw6q 1871 4 this this DT cord-006870-f5w6fw6q 1871 5 retrospective retrospective JJ cord-006870-f5w6fw6q 1871 6 observational observational JJ cord-006870-f5w6fw6q 1871 7 study study NN cord-006870-f5w6fw6q 1871 8 was be VBD cord-006870-f5w6fw6q 1871 9 to to TO cord-006870-f5w6fw6q 1871 10 determine determine VB cord-006870-f5w6fw6q 1871 11 if if IN cord-006870-f5w6fw6q 1871 12 patients patient NNS cord-006870-f5w6fw6q 1871 13 receiving receive VBG cord-006870-f5w6fw6q 1871 14 IV IV NNP cord-006870-f5w6fw6q 1871 15 tPA tPA NNP cord-006870-f5w6fw6q 1871 16 who who WP cord-006870-f5w6fw6q 1871 17 were be VBD cord-006870-f5w6fw6q 1871 18 mobilized mobilize VBN cord-006870-f5w6fw6q 1871 19 earlier early RBR cord-006870-f5w6fw6q 1871 20 were be VBD cord-006870-f5w6fw6q 1871 21 more more RBR cord-006870-f5w6fw6q 1871 22 likely likely JJ cord-006870-f5w6fw6q 1871 23 to to TO cord-006870-f5w6fw6q 1871 24 discharge discharge VB cord-006870-f5w6fw6q 1871 25 home home RB cord-006870-f5w6fw6q 1871 26 . . . cord-006870-f5w6fw6q 1872 1 Medical medical JJ cord-006870-f5w6fw6q 1872 2 records record NNS cord-006870-f5w6fw6q 1872 3 of of IN cord-006870-f5w6fw6q 1872 4 ischemic ischemic JJ cord-006870-f5w6fw6q 1872 5 stroke stroke NN cord-006870-f5w6fw6q 1872 6 patients patient NNS cord-006870-f5w6fw6q 1872 7 who who WP cord-006870-f5w6fw6q 1872 8 received receive VBD cord-006870-f5w6fw6q 1872 9 IV IV NNP cord-006870-f5w6fw6q 1872 10 tPA tPA NNP cord-006870-f5w6fw6q 1872 11 between between IN cord-006870-f5w6fw6q 1872 12 2012 2012 CD cord-006870-f5w6fw6q 1872 13 and and CC cord-006870-f5w6fw6q 1872 14 2016 2016 CD cord-006870-f5w6fw6q 1872 15 at at IN cord-006870-f5w6fw6q 1872 16 two two CD cord-006870-f5w6fw6q 1872 17 urban urban JJ cord-006870-f5w6fw6q 1872 18 facilities facility NNS cord-006870-f5w6fw6q 1872 19 were be VBD cord-006870-f5w6fw6q 1872 20 reviewed review VBN cord-006870-f5w6fw6q 1872 21 for for IN cord-006870-f5w6fw6q 1872 22 mobility mobility NN cord-006870-f5w6fw6q 1872 23 protocol protocol NN cord-006870-f5w6fw6q 1872 24 activities activity NNS cord-006870-f5w6fw6q 1872 25 . . . cord-006870-f5w6fw6q 1873 1 Patients patient NNS cord-006870-f5w6fw6q 1873 2 who who WP cord-006870-f5w6fw6q 1873 3 received receive VBD cord-006870-f5w6fw6q 1873 4 endovascular endovascular JJ cord-006870-f5w6fw6q 1873 5 treatment treatment NN cord-006870-f5w6fw6q 1873 6 , , , cord-006870-f5w6fw6q 1873 7 were be VBD cord-006870-f5w6fw6q 1873 8 placed place VBN cord-006870-f5w6fw6q 1873 9 on on IN cord-006870-f5w6fw6q 1873 10 comfort comfort NN cord-006870-f5w6fw6q 1873 11 care care NN cord-006870-f5w6fw6q 1873 12 day day NN cord-006870-f5w6fw6q 1873 13 zero zero CD cord-006870-f5w6fw6q 1873 14 or or CC cord-006870-f5w6fw6q 1873 15 one one CD cord-006870-f5w6fw6q 1873 16 , , , cord-006870-f5w6fw6q 1873 17 mobilized mobilize VBN cord-006870-f5w6fw6q 1873 18 after after IN cord-006870-f5w6fw6q 1873 19 the the DT cord-006870-f5w6fw6q 1873 20 first first JJ cord-006870-f5w6fw6q 1873 21 24 24 CD cord-006870-f5w6fw6q 1873 22 hours hour NNS cord-006870-f5w6fw6q 1873 23 , , , cord-006870-f5w6fw6q 1873 24 and and CC cord-006870-f5w6fw6q 1873 25 transferred transfer VBN cord-006870-f5w6fw6q 1873 26 out out RP cord-006870-f5w6fw6q 1873 27 or or CC cord-006870-f5w6fw6q 1873 28 left leave VBN cord-006870-f5w6fw6q 1873 29 against against IN cord-006870-f5w6fw6q 1873 30 medical medical JJ cord-006870-f5w6fw6q 1873 31 advice advice NN cord-006870-f5w6fw6q 1873 32 were be VBD cord-006870-f5w6fw6q 1873 33 excluded exclude VBN cord-006870-f5w6fw6q 1873 34 . . . cord-006870-f5w6fw6q 1874 1 Multinomial multinomial JJ cord-006870-f5w6fw6q 1874 2 regression regression NN cord-006870-f5w6fw6q 1874 3 was be VBD cord-006870-f5w6fw6q 1874 4 used use VBN cord-006870-f5w6fw6q 1874 5 to to TO cord-006870-f5w6fw6q 1874 6 determine determine VB cord-006870-f5w6fw6q 1874 7 if if IN cord-006870-f5w6fw6q 1874 8 there there EX cord-006870-f5w6fw6q 1874 9 were be VBD cord-006870-f5w6fw6q 1874 10 significant significant JJ cord-006870-f5w6fw6q 1874 11 differences difference NNS cord-006870-f5w6fw6q 1874 12 in in IN cord-006870-f5w6fw6q 1874 13 patients patient NNS cord-006870-f5w6fw6q 1874 14 ' ' POS cord-006870-f5w6fw6q 1874 15 discharge discharge NN cord-006870-f5w6fw6q 1874 16 status status NN cord-006870-f5w6fw6q 1874 17 by by IN cord-006870-f5w6fw6q 1874 18 time time NN cord-006870-f5w6fw6q 1874 19 first first RB cord-006870-f5w6fw6q 1874 20 mobilized mobilize VBD cord-006870-f5w6fw6q 1874 21 , , , cord-006870-f5w6fw6q 1874 22 adjusting adjust VBG cord-006870-f5w6fw6q 1874 23 for for IN cord-006870-f5w6fw6q 1874 24 stroke stroke NN cord-006870-f5w6fw6q 1874 25 severity severity NN cord-006870-f5w6fw6q 1874 26 using use VBG cord-006870-f5w6fw6q 1874 27 the the DT cord-006870-f5w6fw6q 1874 28 National National NNP cord-006870-f5w6fw6q 1874 29 Institutes Institutes NNPS cord-006870-f5w6fw6q 1874 30 of of IN cord-006870-f5w6fw6q 1874 31 Health Health NNP cord-006870-f5w6fw6q 1874 32 Stroke Stroke NNP cord-006870-f5w6fw6q 1874 33 Scale Scale NNP cord-006870-f5w6fw6q 1874 34 ( ( -LRB- cord-006870-f5w6fw6q 1874 35 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1874 36 ) ) -RRB- cord-006870-f5w6fw6q 1874 37 , , , cord-006870-f5w6fw6q 1874 38 age age NN cord-006870-f5w6fw6q 1874 39 and and CC cord-006870-f5w6fw6q 1874 40 gender gender NN cord-006870-f5w6fw6q 1874 41 . . . cord-006870-f5w6fw6q 1875 1 Of of IN cord-006870-f5w6fw6q 1875 2 the the DT cord-006870-f5w6fw6q 1875 3 268 268 CD cord-006870-f5w6fw6q 1875 4 patients patient NNS cord-006870-f5w6fw6q 1875 5 included include VBN cord-006870-f5w6fw6q 1875 6 , , , cord-006870-f5w6fw6q 1875 7 46.6 46.6 CD cord-006870-f5w6fw6q 1875 8 % % NN cord-006870-f5w6fw6q 1875 9 ( ( -LRB- cord-006870-f5w6fw6q 1875 10 n=125 n=125 NNP cord-006870-f5w6fw6q 1875 11 ) ) -RRB- cord-006870-f5w6fw6q 1875 12 were be VBD cord-006870-f5w6fw6q 1875 13 female female JJ cord-006870-f5w6fw6q 1875 14 , , , cord-006870-f5w6fw6q 1875 15 mean mean JJ cord-006870-f5w6fw6q 1875 16 age age NN cord-006870-f5w6fw6q 1875 17 was be VBD cord-006870-f5w6fw6q 1875 18 68.6 68.6 CD cord-006870-f5w6fw6q 1875 19 ( ( -LRB- cord-006870-f5w6fw6q 1875 20 ±14.8 ±14.8 NNP cord-006870-f5w6fw6q 1875 21 ) ) -RRB- cord-006870-f5w6fw6q 1875 22 , , , cord-006870-f5w6fw6q 1875 23 and and CC cord-006870-f5w6fw6q 1875 24 the the DT cord-006870-f5w6fw6q 1875 25 median median NN cord-006870-f5w6fw6q 1875 26 admit admit VBP cord-006870-f5w6fw6q 1875 27 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1875 28 was be VBD cord-006870-f5w6fw6q 1875 29 5.0 5.0 CD cord-006870-f5w6fw6q 1875 30 [ [ -LRB- cord-006870-f5w6fw6q 1875 31 IQR iqr NN cord-006870-f5w6fw6q 1875 32 : : : cord-006870-f5w6fw6q 1875 33 3.0 3.0 CD cord-006870-f5w6fw6q 1875 34 , , , cord-006870-f5w6fw6q 1875 35 10.0 10.0 CD cord-006870-f5w6fw6q 1875 36 ] ] -RRB- cord-006870-f5w6fw6q 1875 37 . . . cord-006870-f5w6fw6q 1876 1 The the DT cord-006870-f5w6fw6q 1876 2 median median JJ cord-006870-f5w6fw6q 1876 3 time time NN cord-006870-f5w6fw6q 1876 4 first first RB cord-006870-f5w6fw6q 1876 5 mobilized mobilize VBD cord-006870-f5w6fw6q 1876 6 was be VBD cord-006870-f5w6fw6q 1876 7 9.0 9.0 CD cord-006870-f5w6fw6q 1876 8 hours hour NNS cord-006870-f5w6fw6q 1877 1 [ [ -LRB- cord-006870-f5w6fw6q 1877 2 IQR IQR NNP cord-006870-f5w6fw6q 1877 3 : : : cord-006870-f5w6fw6q 1877 4 4.3 4.3 CD cord-006870-f5w6fw6q 1877 5 , , , cord-006870-f5w6fw6q 1877 6 15.0 15.0 CD cord-006870-f5w6fw6q 1877 7 ] ] -RRB- cord-006870-f5w6fw6q 1877 8 , , , cord-006870-f5w6fw6q 1877 9 71.3 71.3 CD cord-006870-f5w6fw6q 1877 10 % % NN cord-006870-f5w6fw6q 1877 11 ( ( -LRB- cord-006870-f5w6fw6q 1877 12 n=191 n=191 NNP cord-006870-f5w6fw6q 1877 13 ) ) -RRB- cord-006870-f5w6fw6q 1877 14 of of IN cord-006870-f5w6fw6q 1877 15 patients patient NNS cord-006870-f5w6fw6q 1877 16 were be VBD cord-006870-f5w6fw6q 1877 17 discharged discharge VBN cord-006870-f5w6fw6q 1877 18 to to IN cord-006870-f5w6fw6q 1877 19 home home NN cord-006870-f5w6fw6q 1877 20 , , , cord-006870-f5w6fw6q 1877 21 12.3 12.3 CD cord-006870-f5w6fw6q 1877 22 % % NN cord-006870-f5w6fw6q 1877 23 ( ( -LRB- cord-006870-f5w6fw6q 1877 24 n=33 n=33 NNP cord-006870-f5w6fw6q 1877 25 ) ) -RRB- cord-006870-f5w6fw6q 1877 26 , , , cord-006870-f5w6fw6q 1877 27 a a DT cord-006870-f5w6fw6q 1877 28 skilled skilled JJ cord-006870-f5w6fw6q 1877 29 nursing nursing NN cord-006870-f5w6fw6q 1877 30 facility facility NN cord-006870-f5w6fw6q 1877 31 ( ( -LRB- cord-006870-f5w6fw6q 1877 32 SNF SNF NNP cord-006870-f5w6fw6q 1877 33 ) ) -RRB- cord-006870-f5w6fw6q 1877 34 , , , cord-006870-f5w6fw6q 1877 35 13.8 13.8 CD cord-006870-f5w6fw6q 1877 36 % % NN cord-006870-f5w6fw6q 1877 37 ( ( -LRB- cord-006870-f5w6fw6q 1877 38 n=37 n=37 NNP cord-006870-f5w6fw6q 1877 39 ) ) -RRB- cord-006870-f5w6fw6q 1877 40 , , , cord-006870-f5w6fw6q 1877 41 an an DT cord-006870-f5w6fw6q 1877 42 inpatient inpatient JJ cord-006870-f5w6fw6q 1877 43 rehab rehab NN cord-006870-f5w6fw6q 1877 44 facility facility NN cord-006870-f5w6fw6q 1877 45 ( ( -LRB- cord-006870-f5w6fw6q 1877 46 IRF IRF NNP cord-006870-f5w6fw6q 1877 47 ) ) -RRB- cord-006870-f5w6fw6q 1877 48 , , , cord-006870-f5w6fw6q 1877 49 and and CC cord-006870-f5w6fw6q 1877 50 2.6 2.6 CD cord-006870-f5w6fw6q 1877 51 % % NN cord-006870-f5w6fw6q 1877 52 ( ( -LRB- cord-006870-f5w6fw6q 1877 53 n=7 n=7 JJ cord-006870-f5w6fw6q 1877 54 ) ) -RRB- cord-006870-f5w6fw6q 1877 55 hospice hospice NN cord-006870-f5w6fw6q 1877 56 or or CC cord-006870-f5w6fw6q 1877 57 expired expire VBD cord-006870-f5w6fw6q 1877 58 . . . cord-006870-f5w6fw6q 1878 1 There there EX cord-006870-f5w6fw6q 1878 2 was be VBD cord-006870-f5w6fw6q 1878 3 suggestive suggestive JJ cord-006870-f5w6fw6q 1878 4 , , , cord-006870-f5w6fw6q 1878 5 but but CC cord-006870-f5w6fw6q 1878 6 inconclusive inconclusive JJ cord-006870-f5w6fw6q 1878 7 evidence evidence NN cord-006870-f5w6fw6q 1878 8 for for IN cord-006870-f5w6fw6q 1878 9 a a DT cord-006870-f5w6fw6q 1878 10 relationship relationship NN cord-006870-f5w6fw6q 1878 11 between between IN cord-006870-f5w6fw6q 1878 12 time time NN cord-006870-f5w6fw6q 1878 13 first first RB cord-006870-f5w6fw6q 1878 14 mobilized mobilize VBD cord-006870-f5w6fw6q 1878 15 and and CC cord-006870-f5w6fw6q 1878 16 discharged discharge VBN cord-006870-f5w6fw6q 1878 17 to to IN cord-006870-f5w6fw6q 1878 18 SNF SNF NNP cord-006870-f5w6fw6q 1878 19 versus versus IN cord-006870-f5w6fw6q 1878 20 home home NN cord-006870-f5w6fw6q 1878 21 ( ( -LRB- cord-006870-f5w6fw6q 1878 22 p=.071 p=.071 NNP cord-006870-f5w6fw6q 1878 23 ) ) -RRB- cord-006870-f5w6fw6q 1878 24 . . . cord-006870-f5w6fw6q 1879 1 For for IN cord-006870-f5w6fw6q 1879 2 every every DT cord-006870-f5w6fw6q 1879 3 one one CD cord-006870-f5w6fw6q 1879 4 hour hour NN cord-006870-f5w6fw6q 1879 5 increase increase NN cord-006870-f5w6fw6q 1879 6 in in IN cord-006870-f5w6fw6q 1879 7 time time NN cord-006870-f5w6fw6q 1879 8 mobilized mobilize VBN cord-006870-f5w6fw6q 1879 9 , , , cord-006870-f5w6fw6q 1879 10 patients patient NNS cord-006870-f5w6fw6q 1879 11 were be VBD cord-006870-f5w6fw6q 1879 12 1.07 1.07 CD cord-006870-f5w6fw6q 1879 13 ( ( -LRB- cord-006870-f5w6fw6q 1879 14 95 95 CD cord-006870-f5w6fw6q 1879 15 % % NN cord-006870-f5w6fw6q 1879 16 CI= ci= CD cord-006870-f5w6fw6q 1879 17 1.00 1.00 CD cord-006870-f5w6fw6q 1879 18 -1.15 -1.15 CD cord-006870-f5w6fw6q 1879 19 ) ) -RRB- cord-006870-f5w6fw6q 1879 20 times time NNS cord-006870-f5w6fw6q 1879 21 more more RBR cord-006870-f5w6fw6q 1879 22 likely likely JJ cord-006870-f5w6fw6q 1879 23 to to TO cord-006870-f5w6fw6q 1879 24 be be VB cord-006870-f5w6fw6q 1879 25 discharged discharge VBN cord-006870-f5w6fw6q 1879 26 to to IN cord-006870-f5w6fw6q 1879 27 SNF SNF NNP cord-006870-f5w6fw6q 1879 28 than than IN cord-006870-f5w6fw6q 1879 29 home home NN cord-006870-f5w6fw6q 1879 30 . . . cord-006870-f5w6fw6q 1880 1 This this DT cord-006870-f5w6fw6q 1880 2 study study NN cord-006870-f5w6fw6q 1880 3 reveals reveal VBZ cord-006870-f5w6fw6q 1880 4 very very RB cord-006870-f5w6fw6q 1880 5 early early JJ cord-006870-f5w6fw6q 1880 6 mobility mobility NN cord-006870-f5w6fw6q 1880 7 is be VBZ cord-006870-f5w6fw6q 1880 8 potentially potentially RB cord-006870-f5w6fw6q 1880 9 efficacious efficacious JJ cord-006870-f5w6fw6q 1880 10 after after IN cord-006870-f5w6fw6q 1880 11 IV IV NNP cord-006870-f5w6fw6q 1880 12 tPA tPA NNP cord-006870-f5w6fw6q 1880 13 . . . cord-006870-f5w6fw6q 1881 1 Longer long JJR cord-006870-f5w6fw6q 1881 2 time time NN cord-006870-f5w6fw6q 1881 3 to to IN cord-006870-f5w6fw6q 1881 4 first first JJ cord-006870-f5w6fw6q 1881 5 mobility mobility NN cord-006870-f5w6fw6q 1881 6 was be VBD cord-006870-f5w6fw6q 1881 7 associated associate VBN cord-006870-f5w6fw6q 1881 8 with with IN cord-006870-f5w6fw6q 1881 9 discharge discharge NN cord-006870-f5w6fw6q 1881 10 to to IN cord-006870-f5w6fw6q 1881 11 skilled skilled JJ cord-006870-f5w6fw6q 1881 12 nursing nursing NN cord-006870-f5w6fw6q 1881 13 facility facility NN cord-006870-f5w6fw6q 1881 14 , , , cord-006870-f5w6fw6q 1881 15 although although IN cord-006870-f5w6fw6q 1881 16 this this DT cord-006870-f5w6fw6q 1881 17 was be VBD cord-006870-f5w6fw6q 1881 18 not not RB cord-006870-f5w6fw6q 1881 19 statistically statistically RB cord-006870-f5w6fw6q 1881 20 significant significant JJ cord-006870-f5w6fw6q 1881 21 . . . cord-006870-f5w6fw6q 1882 1 Medical medical JJ cord-006870-f5w6fw6q 1882 2 management management NN cord-006870-f5w6fw6q 1882 3 of of IN cord-006870-f5w6fw6q 1882 4 cerebral cerebral JJ cord-006870-f5w6fw6q 1882 5 edema edema NN cord-006870-f5w6fw6q 1882 6 after after IN cord-006870-f5w6fw6q 1882 7 large large JJ cord-006870-f5w6fw6q 1882 8 volume volume NN cord-006870-f5w6fw6q 1882 9 stroke stroke NN cord-006870-f5w6fw6q 1882 10 varies vary VBZ cord-006870-f5w6fw6q 1882 11 greatly greatly RB cord-006870-f5w6fw6q 1882 12 across across IN cord-006870-f5w6fw6q 1882 13 institutions institution NNS cord-006870-f5w6fw6q 1882 14 . . . cord-006870-f5w6fw6q 1883 1 Hypertonic Hypertonic NNP cord-006870-f5w6fw6q 1883 2 saline saline NN cord-006870-f5w6fw6q 1883 3 has have VBZ cord-006870-f5w6fw6q 1883 4 emerged emerge VBN cord-006870-f5w6fw6q 1883 5 as as IN cord-006870-f5w6fw6q 1883 6 a a DT cord-006870-f5w6fw6q 1883 7 common common JJ cord-006870-f5w6fw6q 1883 8 treatment treatment NN cord-006870-f5w6fw6q 1883 9 strategy strategy NN cord-006870-f5w6fw6q 1883 10 to to TO cord-006870-f5w6fw6q 1883 11 attempt attempt VB cord-006870-f5w6fw6q 1883 12 to to TO cord-006870-f5w6fw6q 1883 13 reduce reduce VB cord-006870-f5w6fw6q 1883 14 edema edema NN cord-006870-f5w6fw6q 1883 15 and and CC cord-006870-f5w6fw6q 1883 16 theoretically theoretically RB cord-006870-f5w6fw6q 1883 17 prevent prevent VB cord-006870-f5w6fw6q 1883 18 the the DT cord-006870-f5w6fw6q 1883 19 need need NN cord-006870-f5w6fw6q 1883 20 for for IN cord-006870-f5w6fw6q 1883 21 decompressive decompressive JJ cord-006870-f5w6fw6q 1883 22 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 1883 23 . . . cord-006870-f5w6fw6q 1884 1 There there EX cord-006870-f5w6fw6q 1884 2 is be VBZ cord-006870-f5w6fw6q 1884 3 no no DT cord-006870-f5w6fw6q 1884 4 established establish VBN cord-006870-f5w6fw6q 1884 5 protocol protocol NN cord-006870-f5w6fw6q 1884 6 for for IN cord-006870-f5w6fw6q 1884 7 hypertonic hypertonic NNP cord-006870-f5w6fw6q 1884 8 saline saline NNP cord-006870-f5w6fw6q 1884 9 administration administration NN cord-006870-f5w6fw6q 1884 10 and and CC cord-006870-f5w6fw6q 1884 11 there there EX cord-006870-f5w6fw6q 1884 12 have have VBP cord-006870-f5w6fw6q 1884 13 been be VBN cord-006870-f5w6fw6q 1884 14 concerns concern NNS cord-006870-f5w6fw6q 1884 15 regarding regard VBG cord-006870-f5w6fw6q 1884 16 safety safety NN cord-006870-f5w6fw6q 1884 17 . . . cord-006870-f5w6fw6q 1885 1 In in IN cord-006870-f5w6fw6q 1885 2 a a DT cord-006870-f5w6fw6q 1885 3 single single JJ cord-006870-f5w6fw6q 1885 4 - - HYPH cord-006870-f5w6fw6q 1885 5 center center NN cord-006870-f5w6fw6q 1885 6 , , , cord-006870-f5w6fw6q 1885 7 retrospective retrospective JJ cord-006870-f5w6fw6q 1885 8 analysis analysis NN cord-006870-f5w6fw6q 1885 9 we -PRON- PRP cord-006870-f5w6fw6q 1885 10 identified identify VBD cord-006870-f5w6fw6q 1885 11 patients patient NNS cord-006870-f5w6fw6q 1885 12 who who WP cord-006870-f5w6fw6q 1885 13 received receive VBD cord-006870-f5w6fw6q 1885 14 hypertonic hypertonic JJ cord-006870-f5w6fw6q 1885 15 saline saline NN cord-006870-f5w6fw6q 1885 16 for for IN cord-006870-f5w6fw6q 1885 17 malignant malignant JJ cord-006870-f5w6fw6q 1885 18 edema edema NN cord-006870-f5w6fw6q 1885 19 after after IN cord-006870-f5w6fw6q 1885 20 an an DT cord-006870-f5w6fw6q 1885 21 ischemic ischemic JJ cord-006870-f5w6fw6q 1885 22 stroke stroke NN cord-006870-f5w6fw6q 1885 23 involving involve VBG cord-006870-f5w6fw6q 1885 24 the the DT cord-006870-f5w6fw6q 1885 25 entire entire JJ cord-006870-f5w6fw6q 1885 26 hemisphere hemisphere NN cord-006870-f5w6fw6q 1885 27 or or CC cord-006870-f5w6fw6q 1885 28 diffuse diffuse VB cord-006870-f5w6fw6q 1885 29 middle middle JJ cord-006870-f5w6fw6q 1885 30 cerebral cerebral JJ cord-006870-f5w6fw6q 1885 31 artery artery NN cord-006870-f5w6fw6q 1885 32 ( ( -LRB- cord-006870-f5w6fw6q 1885 33 MCA MCA NNP cord-006870-f5w6fw6q 1885 34 ) ) -RRB- cord-006870-f5w6fw6q 1885 35 territory territory NN cord-006870-f5w6fw6q 1885 36 . . . cord-006870-f5w6fw6q 1886 1 We -PRON- PRP cord-006870-f5w6fw6q 1886 2 compared compare VBD cord-006870-f5w6fw6q 1886 3 patients patient NNS cord-006870-f5w6fw6q 1886 4 who who WP cord-006870-f5w6fw6q 1886 5 received receive VBD cord-006870-f5w6fw6q 1886 6 continuous continuous JJ cord-006870-f5w6fw6q 1886 7 infusions infusion NNS cord-006870-f5w6fw6q 1886 8 of of IN cord-006870-f5w6fw6q 1886 9 2 2 CD cord-006870-f5w6fw6q 1886 10 % % NN cord-006870-f5w6fw6q 1886 11 or or CC cord-006870-f5w6fw6q 1886 12 3 3 CD cord-006870-f5w6fw6q 1886 13 % % NN cord-006870-f5w6fw6q 1886 14 hypertonic hypertonic JJ cord-006870-f5w6fw6q 1886 15 saline saline NN cord-006870-f5w6fw6q 1886 16 to to IN cord-006870-f5w6fw6q 1886 17 those those DT cord-006870-f5w6fw6q 1886 18 who who WP cord-006870-f5w6fw6q 1886 19 received receive VBD cord-006870-f5w6fw6q 1886 20 continuous continuous JJ cord-006870-f5w6fw6q 1886 21 infusions infusion NNS cord-006870-f5w6fw6q 1886 22 with with IN cord-006870-f5w6fw6q 1886 23 boluses bolus NNS cord-006870-f5w6fw6q 1886 24 of of IN cord-006870-f5w6fw6q 1886 25 23.4 23.4 CD cord-006870-f5w6fw6q 1886 26 % % NN cord-006870-f5w6fw6q 1886 27 . . . cord-006870-f5w6fw6q 1887 1 The the DT cord-006870-f5w6fw6q 1887 2 primary primary JJ cord-006870-f5w6fw6q 1887 3 endpoint endpoint NN cord-006870-f5w6fw6q 1887 4 was be VBD cord-006870-f5w6fw6q 1887 5 time time NN cord-006870-f5w6fw6q 1887 6 to to TO cord-006870-f5w6fw6q 1887 7 goal goal VB cord-006870-f5w6fw6q 1887 8 sodium sodium NN cord-006870-f5w6fw6q 1887 9 ( ( -LRB- cord-006870-f5w6fw6q 1887 10 150 150 CD cord-006870-f5w6fw6q 1887 11 ) ) -RRB- cord-006870-f5w6fw6q 1887 12 . . . cord-006870-f5w6fw6q 1888 1 Secondary secondary JJ cord-006870-f5w6fw6q 1888 2 endpoints endpoint NNS cord-006870-f5w6fw6q 1888 3 included include VBD cord-006870-f5w6fw6q 1888 4 the the DT cord-006870-f5w6fw6q 1888 5 need need NN cord-006870-f5w6fw6q 1888 6 for for IN cord-006870-f5w6fw6q 1888 7 surgical surgical JJ cord-006870-f5w6fw6q 1888 8 decompression decompression NN cord-006870-f5w6fw6q 1888 9 and and CC cord-006870-f5w6fw6q 1888 10 adverse adverse JJ cord-006870-f5w6fw6q 1888 11 events event NNS cord-006870-f5w6fw6q 1888 12 . . . cord-006870-f5w6fw6q 1889 1 We -PRON- PRP cord-006870-f5w6fw6q 1889 2 included include VBD cord-006870-f5w6fw6q 1889 3 28 28 CD cord-006870-f5w6fw6q 1889 4 patients patient NNS cord-006870-f5w6fw6q 1889 5 who who WP cord-006870-f5w6fw6q 1889 6 received receive VBD cord-006870-f5w6fw6q 1889 7 only only RB cord-006870-f5w6fw6q 1889 8 continuous continuous JJ cord-006870-f5w6fw6q 1889 9 infusions infusion NNS cord-006870-f5w6fw6q 1889 10 of of IN cord-006870-f5w6fw6q 1889 11 hypertonic hypertonic JJ cord-006870-f5w6fw6q 1889 12 saline saline NN cord-006870-f5w6fw6q 1889 13 and and CC cord-006870-f5w6fw6q 1889 14 20 20 CD cord-006870-f5w6fw6q 1889 15 patients patient NNS cord-006870-f5w6fw6q 1889 16 who who WP cord-006870-f5w6fw6q 1889 17 received receive VBD cord-006870-f5w6fw6q 1889 18 a a DT cord-006870-f5w6fw6q 1889 19 combination combination NN cord-006870-f5w6fw6q 1889 20 of of IN cord-006870-f5w6fw6q 1889 21 continuous continuous JJ cord-006870-f5w6fw6q 1889 22 infusions infusion NNS cord-006870-f5w6fw6q 1889 23 and and CC cord-006870-f5w6fw6q 1889 24 bolus bolus NN cord-006870-f5w6fw6q 1889 25 doses dose NNS cord-006870-f5w6fw6q 1889 26 . . . cord-006870-f5w6fw6q 1890 1 We -PRON- PRP cord-006870-f5w6fw6q 1890 2 found find VBD cord-006870-f5w6fw6q 1890 3 no no DT cord-006870-f5w6fw6q 1890 4 significant significant JJ cord-006870-f5w6fw6q 1890 5 difference difference NN cord-006870-f5w6fw6q 1890 6 between between IN cord-006870-f5w6fw6q 1890 7 number number NN cord-006870-f5w6fw6q 1890 8 of of IN cord-006870-f5w6fw6q 1890 9 patients patient NNS cord-006870-f5w6fw6q 1890 10 who who WP cord-006870-f5w6fw6q 1890 11 reached reach VBD cord-006870-f5w6fw6q 1890 12 goal goal NN cord-006870-f5w6fw6q 1890 13 sodium sodium NN cord-006870-f5w6fw6q 1890 14 ( ( -LRB- cord-006870-f5w6fw6q 1890 15 14 14 CD cord-006870-f5w6fw6q 1890 16 vs vs IN cord-006870-f5w6fw6q 1890 17 14 14 CD cord-006870-f5w6fw6q 1890 18 respectively respectively RB cord-006870-f5w6fw6q 1890 19 , , , cord-006870-f5w6fw6q 1890 20 p=0.17 p=0.17 NNP cord-006870-f5w6fw6q 1890 21 ) ) -RRB- cord-006870-f5w6fw6q 1890 22 or or CC cord-006870-f5w6fw6q 1890 23 time time NN cord-006870-f5w6fw6q 1890 24 to to TO cord-006870-f5w6fw6q 1890 25 goal goal VB cord-006870-f5w6fw6q 1890 26 sodium sodium NN cord-006870-f5w6fw6q 1890 27 ( ( -LRB- cord-006870-f5w6fw6q 1890 28 20 20 CD cord-006870-f5w6fw6q 1890 29 hours hour NNS cord-006870-f5w6fw6q 1890 30 vs vs IN cord-006870-f5w6fw6q 1890 31 23.5 23.5 CD cord-006870-f5w6fw6q 1890 32 hours hour NNS cord-006870-f5w6fw6q 1890 33 , , , cord-006870-f5w6fw6q 1890 34 p=0.68 p=0.68 NN cord-006870-f5w6fw6q 1890 35 ) ) -RRB- cord-006870-f5w6fw6q 1890 36 . . . cord-006870-f5w6fw6q 1891 1 There there EX cord-006870-f5w6fw6q 1891 2 was be VBD cord-006870-f5w6fw6q 1891 3 a a DT cord-006870-f5w6fw6q 1891 4 significant significant JJ cord-006870-f5w6fw6q 1891 5 difference difference NN cord-006870-f5w6fw6q 1891 6 in in IN cord-006870-f5w6fw6q 1891 7 the the DT cord-006870-f5w6fw6q 1891 8 number number NN cord-006870-f5w6fw6q 1891 9 of of IN cord-006870-f5w6fw6q 1891 10 patients patient NNS cord-006870-f5w6fw6q 1891 11 who who WP cord-006870-f5w6fw6q 1891 12 underwent undergo VBD cord-006870-f5w6fw6q 1891 13 surgical surgical JJ cord-006870-f5w6fw6q 1891 14 decompression decompression NN cord-006870-f5w6fw6q 1891 15 ( ( -LRB- cord-006870-f5w6fw6q 1891 16 4 4 CD cord-006870-f5w6fw6q 1891 17 vs vs IN cord-006870-f5w6fw6q 1891 18 8 8 CD cord-006870-f5w6fw6q 1891 19 , , , cord-006870-f5w6fw6q 1891 20 p=0.04 p=0.04 NNP cord-006870-f5w6fw6q 1891 21 ) ) -RRB- cord-006870-f5w6fw6q 1891 22 . . . cord-006870-f5w6fw6q 1892 1 There there EX cord-006870-f5w6fw6q 1892 2 was be VBD cord-006870-f5w6fw6q 1892 3 not not RB cord-006870-f5w6fw6q 1892 4 a a DT cord-006870-f5w6fw6q 1892 5 significant significant JJ cord-006870-f5w6fw6q 1892 6 difference difference NN cord-006870-f5w6fw6q 1892 7 in in IN cord-006870-f5w6fw6q 1892 8 the the DT cord-006870-f5w6fw6q 1892 9 rate rate NN cord-006870-f5w6fw6q 1892 10 of of IN cord-006870-f5w6fw6q 1892 11 acute acute JJ cord-006870-f5w6fw6q 1892 12 kidney kidney NN cord-006870-f5w6fw6q 1892 13 injury injury NN cord-006870-f5w6fw6q 1892 14 or or CC cord-006870-f5w6fw6q 1892 15 development development NN cord-006870-f5w6fw6q 1892 16 of of IN cord-006870-f5w6fw6q 1892 17 acidosis acidosis NN cord-006870-f5w6fw6q 1892 18 between between IN cord-006870-f5w6fw6q 1892 19 groups group NNS cord-006870-f5w6fw6q 1892 20 ( ( -LRB- cord-006870-f5w6fw6q 1892 21 5 5 CD cord-006870-f5w6fw6q 1892 22 vs. vs. NN cord-006870-f5w6fw6q 1892 23 5 5 CD cord-006870-f5w6fw6q 1892 24 , , , cord-006870-f5w6fw6q 1892 25 p=0.55 p=0.55 NNP cord-006870-f5w6fw6q 1892 26 ) ) -RRB- cord-006870-f5w6fw6q 1892 27 . . . cord-006870-f5w6fw6q 1893 1 Both both DT cord-006870-f5w6fw6q 1893 2 hypertonic hypertonic JJ cord-006870-f5w6fw6q 1893 3 strategies strategy NNS cord-006870-f5w6fw6q 1893 4 appear appear VBP cord-006870-f5w6fw6q 1893 5 to to TO cord-006870-f5w6fw6q 1893 6 be be VB cord-006870-f5w6fw6q 1893 7 safe safe JJ cord-006870-f5w6fw6q 1893 8 . . . cord-006870-f5w6fw6q 1894 1 Bolus bolus NN cord-006870-f5w6fw6q 1894 2 dosing dosing NN cord-006870-f5w6fw6q 1894 3 , , , cord-006870-f5w6fw6q 1894 4 on on IN cord-006870-f5w6fw6q 1894 5 review review NN cord-006870-f5w6fw6q 1894 6 , , , cord-006870-f5w6fw6q 1894 7 was be VBD cord-006870-f5w6fw6q 1894 8 more more RBR cord-006870-f5w6fw6q 1894 9 often often RB cord-006870-f5w6fw6q 1894 10 instituted institute VBN cord-006870-f5w6fw6q 1894 11 during during IN cord-006870-f5w6fw6q 1894 12 clinical clinical JJ cord-006870-f5w6fw6q 1894 13 deterioration deterioration NN cord-006870-f5w6fw6q 1894 14 , , , cord-006870-f5w6fw6q 1894 15 accounting account VBG cord-006870-f5w6fw6q 1894 16 for for IN cord-006870-f5w6fw6q 1894 17 the the DT cord-006870-f5w6fw6q 1894 18 higher high JJR cord-006870-f5w6fw6q 1894 19 rate rate NN cord-006870-f5w6fw6q 1894 20 of of IN cord-006870-f5w6fw6q 1894 21 surgical surgical JJ cord-006870-f5w6fw6q 1894 22 intervention intervention NN cord-006870-f5w6fw6q 1894 23 . . . cord-006870-f5w6fw6q 1895 1 We -PRON- PRP cord-006870-f5w6fw6q 1895 2 feel feel VBP cord-006870-f5w6fw6q 1895 3 we -PRON- PRP cord-006870-f5w6fw6q 1895 4 can can MD cord-006870-f5w6fw6q 1895 5 safely safely RB cord-006870-f5w6fw6q 1895 6 be be VB cord-006870-f5w6fw6q 1895 7 more more RBR cord-006870-f5w6fw6q 1895 8 aggressive aggressive JJ cord-006870-f5w6fw6q 1895 9 earlier early RBR cord-006870-f5w6fw6q 1895 10 in in IN cord-006870-f5w6fw6q 1895 11 the the DT cord-006870-f5w6fw6q 1895 12 clinical clinical JJ cord-006870-f5w6fw6q 1895 13 course course NN cord-006870-f5w6fw6q 1895 14 to to TO cord-006870-f5w6fw6q 1895 15 potentially potentially RB cord-006870-f5w6fw6q 1895 16 avoid avoid VB cord-006870-f5w6fw6q 1895 17 surgical surgical JJ cord-006870-f5w6fw6q 1895 18 decompression decompression NN cord-006870-f5w6fw6q 1895 19 . . . cord-006870-f5w6fw6q 1896 1 Furthermore furthermore RB cord-006870-f5w6fw6q 1896 2 , , , cord-006870-f5w6fw6q 1896 3 we -PRON- PRP cord-006870-f5w6fw6q 1896 4 may may MD cord-006870-f5w6fw6q 1896 5 need need VB cord-006870-f5w6fw6q 1896 6 to to TO cord-006870-f5w6fw6q 1896 7 look look VB cord-006870-f5w6fw6q 1896 8 more more RBR cord-006870-f5w6fw6q 1896 9 closely closely RB cord-006870-f5w6fw6q 1896 10 at at IN cord-006870-f5w6fw6q 1896 11 our -PRON- PRP$ cord-006870-f5w6fw6q 1896 12 target target NN cord-006870-f5w6fw6q 1896 13 sodium sodium NN cord-006870-f5w6fw6q 1896 14 , , , cord-006870-f5w6fw6q 1896 15 evaluating evaluate VBG cord-006870-f5w6fw6q 1896 16 whether whether IN cord-006870-f5w6fw6q 1896 17 it -PRON- PRP cord-006870-f5w6fw6q 1896 18 should should MD cord-006870-f5w6fw6q 1896 19 be be VB cord-006870-f5w6fw6q 1896 20 based base VBN cord-006870-f5w6fw6q 1896 21 on on IN cord-006870-f5w6fw6q 1896 22 the the DT cord-006870-f5w6fw6q 1896 23 patient patient NN cord-006870-f5w6fw6q 1896 24 's 's POS cord-006870-f5w6fw6q 1896 25 baseline baseline JJ cord-006870-f5w6fw6q 1896 26 sodium sodium NN cord-006870-f5w6fw6q 1896 27 or or CC cord-006870-f5w6fw6q 1896 28 a a DT cord-006870-f5w6fw6q 1896 29 universal universal JJ cord-006870-f5w6fw6q 1896 30 value value NN cord-006870-f5w6fw6q 1896 31 . . . cord-006870-f5w6fw6q 1897 1 Even even RB cord-006870-f5w6fw6q 1897 2 though though IN cord-006870-f5w6fw6q 1897 3 recanalization recanalization NN cord-006870-f5w6fw6q 1897 4 is be VBZ cord-006870-f5w6fw6q 1897 5 strongly strongly RB cord-006870-f5w6fw6q 1897 6 associated associate VBN cord-006870-f5w6fw6q 1897 7 with with IN cord-006870-f5w6fw6q 1897 8 improved improved JJ cord-006870-f5w6fw6q 1897 9 functional functional JJ cord-006870-f5w6fw6q 1897 10 outcomes outcome NNS cord-006870-f5w6fw6q 1897 11 and and CC cord-006870-f5w6fw6q 1897 12 reduced reduce VBN cord-006870-f5w6fw6q 1897 13 mortality mortality NN cord-006870-f5w6fw6q 1897 14 , , , cord-006870-f5w6fw6q 1897 15 clinical clinical JJ cord-006870-f5w6fw6q 1897 16 benefit benefit NN cord-006870-f5w6fw6q 1897 17 from from IN cord-006870-f5w6fw6q 1897 18 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 1897 19 is be VBZ cord-006870-f5w6fw6q 1897 20 reduced reduce VBN cord-006870-f5w6fw6q 1897 21 as as IN cord-006870-f5w6fw6q 1897 22 stroke stroke NN cord-006870-f5w6fw6q 1897 23 onset onset NN cord-006870-f5w6fw6q 1897 24 to to IN cord-006870-f5w6fw6q 1897 25 treatment treatment NN cord-006870-f5w6fw6q 1897 26 time time NN cord-006870-f5w6fw6q 1897 27 increases increase NNS cord-006870-f5w6fw6q 1897 28 . . . cord-006870-f5w6fw6q 1898 1 In in IN cord-006870-f5w6fw6q 1898 2 the the DT cord-006870-f5w6fw6q 1898 3 recent recent JJ cord-006870-f5w6fw6q 1898 4 study study NN cord-006870-f5w6fw6q 1898 5 , , , cord-006870-f5w6fw6q 1898 6 endovascular endovascular JJ cord-006870-f5w6fw6q 1898 7 treatment(EVT treatment(evt NN cord-006870-f5w6fw6q 1898 8 ) ) -RRB- cord-006870-f5w6fw6q 1898 9 has have VBZ cord-006870-f5w6fw6q 1898 10 been be VBN cord-006870-f5w6fw6q 1898 11 demonstrated demonstrate VBN cord-006870-f5w6fw6q 1898 12 to to TO cord-006870-f5w6fw6q 1898 13 improve improve VB cord-006870-f5w6fw6q 1898 14 functional functional JJ cord-006870-f5w6fw6q 1898 15 outcome outcome NN cord-006870-f5w6fw6q 1898 16 in in IN cord-006870-f5w6fw6q 1898 17 patients patient NNS cord-006870-f5w6fw6q 1898 18 with with IN cord-006870-f5w6fw6q 1898 19 acute acute JJ cord-006870-f5w6fw6q 1898 20 ischemic ischemic JJ cord-006870-f5w6fw6q 1898 21 stroke stroke NN cord-006870-f5w6fw6q 1898 22 ( ( -LRB- cord-006870-f5w6fw6q 1898 23 AIS AIS NNP cord-006870-f5w6fw6q 1898 24 ) ) -RRB- cord-006870-f5w6fw6q 1898 25 within within IN cord-006870-f5w6fw6q 1898 26 the the DT cord-006870-f5w6fw6q 1898 27 time time NN cord-006870-f5w6fw6q 1898 28 window window NN cord-006870-f5w6fw6q 1898 29 of of IN cord-006870-f5w6fw6q 1898 30 onset onset NN cord-006870-f5w6fw6q 1898 31 to to IN cord-006870-f5w6fw6q 1898 32 6 6 CD cord-006870-f5w6fw6q 1898 33 or or CC cord-006870-f5w6fw6q 1898 34 8 8 CD cord-006870-f5w6fw6q 1898 35 hours hour NNS cord-006870-f5w6fw6q 1898 36 . . . cord-006870-f5w6fw6q 1899 1 However however RB cord-006870-f5w6fw6q 1899 2 , , , cord-006870-f5w6fw6q 1899 3 beyond beyond IN cord-006870-f5w6fw6q 1899 4 usual usual JJ cord-006870-f5w6fw6q 1899 5 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 1899 6 time time NN cord-006870-f5w6fw6q 1899 7 window window NN cord-006870-f5w6fw6q 1899 8 , , , cord-006870-f5w6fw6q 1899 9 early early JJ cord-006870-f5w6fw6q 1899 10 neurologic neurologic JJ cord-006870-f5w6fw6q 1899 11 deterioration(END deterioration(END NNS cord-006870-f5w6fw6q 1899 12 ) ) -RRB- cord-006870-f5w6fw6q 1899 13 related relate VBN cord-006870-f5w6fw6q 1899 14 with with IN cord-006870-f5w6fw6q 1899 15 proximal proximal JJ cord-006870-f5w6fw6q 1899 16 artery artery NN cord-006870-f5w6fw6q 1899 17 occlusion occlusion NN cord-006870-f5w6fw6q 1899 18 is be VBZ cord-006870-f5w6fw6q 1899 19 not not RB cord-006870-f5w6fw6q 1899 20 uncommon uncommon JJ cord-006870-f5w6fw6q 1899 21 in in IN cord-006870-f5w6fw6q 1899 22 AIS AIS NNP cord-006870-f5w6fw6q 1899 23 . . . cord-006870-f5w6fw6q 1900 1 With with IN cord-006870-f5w6fw6q 1900 2 this this DT cord-006870-f5w6fw6q 1900 3 , , , cord-006870-f5w6fw6q 1900 4 we -PRON- PRP cord-006870-f5w6fw6q 1900 5 report report VBP cord-006870-f5w6fw6q 1900 6 AIS AIS NNP cord-006870-f5w6fw6q 1900 7 case case NN cord-006870-f5w6fw6q 1900 8 series series NN cord-006870-f5w6fw6q 1900 9 treated treat VBN cord-006870-f5w6fw6q 1900 10 with with IN cord-006870-f5w6fw6q 1900 11 EVT evt NN cord-006870-f5w6fw6q 1900 12 because because IN cord-006870-f5w6fw6q 1900 13 of of IN cord-006870-f5w6fw6q 1900 14 END end NN cord-006870-f5w6fw6q 1900 15 related relate VBN cord-006870-f5w6fw6q 1900 16 proximal proximal JJ cord-006870-f5w6fw6q 1900 17 artery artery NN cord-006870-f5w6fw6q 1900 18 occlusion occlusion NN cord-006870-f5w6fw6q 1900 19 . . . cord-006870-f5w6fw6q 1901 1 From from IN cord-006870-f5w6fw6q 1901 2 January January NNP cord-006870-f5w6fw6q 1901 3 2012 2012 CD cord-006870-f5w6fw6q 1901 4 through through IN cord-006870-f5w6fw6q 1901 5 March March NNP cord-006870-f5w6fw6q 1901 6 2017 2017 CD cord-006870-f5w6fw6q 1901 7 , , , cord-006870-f5w6fw6q 1901 8 all all DT cord-006870-f5w6fw6q 1901 9 261 261 CD cord-006870-f5w6fw6q 1901 10 patients patient NNS cord-006870-f5w6fw6q 1901 11 underwent undergo VBD cord-006870-f5w6fw6q 1901 12 IAT IAT NNP cord-006870-f5w6fw6q 1901 13 for for IN cord-006870-f5w6fw6q 1901 14 AIS AIS NNP cord-006870-f5w6fw6q 1901 15 with with IN cord-006870-f5w6fw6q 1901 16 anterior anterior JJ cord-006870-f5w6fw6q 1901 17 circulation circulation NN cord-006870-f5w6fw6q 1901 18 stroke stroke NN cord-006870-f5w6fw6q 1901 19 . . . cord-006870-f5w6fw6q 1902 1 Among among IN cord-006870-f5w6fw6q 1902 2 them -PRON- PRP cord-006870-f5w6fw6q 1902 3 , , , cord-006870-f5w6fw6q 1902 4 twenty twenty CD cord-006870-f5w6fw6q 1902 5 - - HYPH cord-006870-f5w6fw6q 1902 6 four four CD cord-006870-f5w6fw6q 1902 7 patients patient NNS cord-006870-f5w6fw6q 1902 8 underwent undergo VBD cord-006870-f5w6fw6q 1902 9 EVT evt NN cord-006870-f5w6fw6q 1902 10 due due JJ cord-006870-f5w6fw6q 1902 11 to to IN cord-006870-f5w6fw6q 1902 12 END END NNP cord-006870-f5w6fw6q 1902 13 . . . cord-006870-f5w6fw6q 1903 1 At at IN cord-006870-f5w6fw6q 1903 2 admission admission NN cord-006870-f5w6fw6q 1903 3 , , , cord-006870-f5w6fw6q 1903 4 all all DT cord-006870-f5w6fw6q 1903 5 twenty twenty CD cord-006870-f5w6fw6q 1903 6 - - HYPH cord-006870-f5w6fw6q 1903 7 four four CD cord-006870-f5w6fw6q 1903 8 patients patient NNS cord-006870-f5w6fw6q 1903 9 showed show VBD cord-006870-f5w6fw6q 1903 10 near near RB cord-006870-f5w6fw6q 1903 11 to to TO cord-006870-f5w6fw6q 1903 12 complete complete JJ cord-006870-f5w6fw6q 1903 13 occlusion occlusion NN cord-006870-f5w6fw6q 1903 14 of of IN cord-006870-f5w6fw6q 1903 15 a a DT cord-006870-f5w6fw6q 1903 16 proximal proximal JJ cord-006870-f5w6fw6q 1903 17 artery artery NN cord-006870-f5w6fw6q 1903 18 and and CC cord-006870-f5w6fw6q 1903 19 had have VBD cord-006870-f5w6fw6q 1903 20 diffusion diffusion NN cord-006870-f5w6fw6q 1903 21 - - HYPH cord-006870-f5w6fw6q 1903 22 perfusion perfusion NN cord-006870-f5w6fw6q 1903 23 mismatch mismatch NN cord-006870-f5w6fw6q 1903 24 . . . cord-006870-f5w6fw6q 1904 1 Mean mean JJ cord-006870-f5w6fw6q 1904 2 age age NN cord-006870-f5w6fw6q 1904 3 was be VBD cord-006870-f5w6fw6q 1904 4 68 68 CD cord-006870-f5w6fw6q 1904 5 . . . cord-006870-f5w6fw6q 1905 1 Initial initial JJ cord-006870-f5w6fw6q 1905 2 median median JJ cord-006870-f5w6fw6q 1905 3 initial initial JJ cord-006870-f5w6fw6q 1905 4 National National NNP cord-006870-f5w6fw6q 1905 5 Institutes Institutes NNPS cord-006870-f5w6fw6q 1905 6 of of IN cord-006870-f5w6fw6q 1905 7 Health Health NNP cord-006870-f5w6fw6q 1905 8 Stroke Stroke NNP cord-006870-f5w6fw6q 1905 9 Scale Scale NNP cord-006870-f5w6fw6q 1905 10 ( ( -LRB- cord-006870-f5w6fw6q 1905 11 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1905 12 ) ) -RRB- cord-006870-f5w6fw6q 1905 13 was be VBD cord-006870-f5w6fw6q 1905 14 5 5 CD cord-006870-f5w6fw6q 1905 15 and and CC cord-006870-f5w6fw6q 1905 16 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1905 17 after after IN cord-006870-f5w6fw6q 1905 18 END END NNP cord-006870-f5w6fw6q 1905 19 was be VBD cord-006870-f5w6fw6q 1905 20 12 12 CD cord-006870-f5w6fw6q 1905 21 . . . cord-006870-f5w6fw6q 1906 1 All all DT cord-006870-f5w6fw6q 1906 2 patients patient NNS cord-006870-f5w6fw6q 1906 3 had have VBD cord-006870-f5w6fw6q 1906 4 diffusion diffusion NN cord-006870-f5w6fw6q 1906 5 - - HYPH cord-006870-f5w6fw6q 1906 6 perfusion perfusion NN cord-006870-f5w6fw6q 1906 7 mismatch mismatch NN cord-006870-f5w6fw6q 1906 8 over over IN cord-006870-f5w6fw6q 1906 9 200 200 CD cord-006870-f5w6fw6q 1906 10 % % NN cord-006870-f5w6fw6q 1906 11 . . . cord-006870-f5w6fw6q 1907 1 Seven seven CD cord-006870-f5w6fw6q 1907 2 patients patient NNS cord-006870-f5w6fw6q 1907 3 treated treat VBN cord-006870-f5w6fw6q 1907 4 with with IN cord-006870-f5w6fw6q 1907 5 IV IV NNP cord-006870-f5w6fw6q 1907 6 - - HYPH cord-006870-f5w6fw6q 1907 7 tPA tPA NNP cord-006870-f5w6fw6q 1907 8 before before IN cord-006870-f5w6fw6q 1907 9 EVT EVT NNP cord-006870-f5w6fw6q 1907 10 . . . cord-006870-f5w6fw6q 1908 1 Good good JJ cord-006870-f5w6fw6q 1908 2 recanalization recanalization NN cord-006870-f5w6fw6q 1908 3 ( ( -LRB- cord-006870-f5w6fw6q 1908 4 TICI TICI NNP cord-006870-f5w6fw6q 1908 5 2b/3 2b/3 CD cord-006870-f5w6fw6q 1908 6 ) ) -RRB- cord-006870-f5w6fw6q 1908 7 was be VBD cord-006870-f5w6fw6q 1908 8 achieved achieve VBN cord-006870-f5w6fw6q 1908 9 in in IN cord-006870-f5w6fw6q 1908 10 91.7 91.7 CD cord-006870-f5w6fw6q 1908 11 % % NN cord-006870-f5w6fw6q 1908 12 . . . cord-006870-f5w6fw6q 1909 1 The the DT cord-006870-f5w6fw6q 1909 2 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1909 3 complication complication NN cord-006870-f5w6fw6q 1909 4 was be VBD cord-006870-f5w6fw6q 1909 5 seen see VBN cord-006870-f5w6fw6q 1909 6 in in IN cord-006870-f5w6fw6q 1909 7 the the DT cord-006870-f5w6fw6q 1909 8 follow follow NN cord-006870-f5w6fw6q 1909 9 - - HYPH cord-006870-f5w6fw6q 1909 10 up up NN cord-006870-f5w6fw6q 1909 11 computed compute VBN cord-006870-f5w6fw6q 1909 12 tomography tomography NN cord-006870-f5w6fw6q 1909 13 scan scan NN cord-006870-f5w6fw6q 1909 14 in in IN cord-006870-f5w6fw6q 1909 15 4 4 CD cord-006870-f5w6fw6q 1909 16 of of IN cord-006870-f5w6fw6q 1909 17 24 24 CD cord-006870-f5w6fw6q 1909 18 cases case NNS cord-006870-f5w6fw6q 1909 19 : : : cord-006870-f5w6fw6q 1909 20 three three CD cord-006870-f5w6fw6q 1909 21 were be VBD cord-006870-f5w6fw6q 1909 22 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 1909 23 transformation transformation NN cord-006870-f5w6fw6q 1909 24 , , , cord-006870-f5w6fw6q 1909 25 another another DT cord-006870-f5w6fw6q 1909 26 was be VBD cord-006870-f5w6fw6q 1909 27 the the DT cord-006870-f5w6fw6q 1909 28 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 1909 29 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1909 30 . . . cord-006870-f5w6fw6q 1910 1 The the DT cord-006870-f5w6fw6q 1910 2 thromboembolic thromboembolic JJ cord-006870-f5w6fw6q 1910 3 mortality mortality NN cord-006870-f5w6fw6q 1910 4 case case NN cord-006870-f5w6fw6q 1910 5 . . . cord-006870-f5w6fw6q 1911 1 In in IN cord-006870-f5w6fw6q 1911 2 our -PRON- PRP$ cord-006870-f5w6fw6q 1911 3 report report NN cord-006870-f5w6fw6q 1911 4 , , , cord-006870-f5w6fw6q 1911 5 EVT evt NN cord-006870-f5w6fw6q 1911 6 in in IN cord-006870-f5w6fw6q 1911 7 AIS AIS NNP cord-006870-f5w6fw6q 1911 8 with with IN cord-006870-f5w6fw6q 1911 9 END END NNP cord-006870-f5w6fw6q 1911 10 achieved achieve VBN cord-006870-f5w6fw6q 1911 11 safe safe JJ cord-006870-f5w6fw6q 1911 12 and and CC cord-006870-f5w6fw6q 1911 13 successful successful JJ cord-006870-f5w6fw6q 1911 14 recanalization recanalization NN cord-006870-f5w6fw6q 1911 15 . . . cord-006870-f5w6fw6q 1912 1 And and CC cord-006870-f5w6fw6q 1912 2 successful successful JJ cord-006870-f5w6fw6q 1912 3 recanalization recanalization NN cord-006870-f5w6fw6q 1912 4 was be VBD cord-006870-f5w6fw6q 1912 5 associated associate VBN cord-006870-f5w6fw6q 1912 6 with with IN cord-006870-f5w6fw6q 1912 7 good good JJ cord-006870-f5w6fw6q 1912 8 clinical clinical JJ cord-006870-f5w6fw6q 1912 9 outcome outcome NN cord-006870-f5w6fw6q 1912 10 . . . cord-006870-f5w6fw6q 1913 1 We -PRON- PRP cord-006870-f5w6fw6q 1913 2 think think VBP cord-006870-f5w6fw6q 1913 3 EVT EVT NNP cord-006870-f5w6fw6q 1913 4 could could MD cord-006870-f5w6fw6q 1913 5 be be VB cord-006870-f5w6fw6q 1913 6 a a DT cord-006870-f5w6fw6q 1913 7 useful useful JJ cord-006870-f5w6fw6q 1913 8 method method NN cord-006870-f5w6fw6q 1913 9 in in IN cord-006870-f5w6fw6q 1913 10 case case NN cord-006870-f5w6fw6q 1913 11 of of IN cord-006870-f5w6fw6q 1913 12 END end NN cord-006870-f5w6fw6q 1913 13 in in IN cord-006870-f5w6fw6q 1913 14 AIS AIS NNP cord-006870-f5w6fw6q 1913 15 patients patient NNS cord-006870-f5w6fw6q 1913 16 with with IN cord-006870-f5w6fw6q 1913 17 proximal proximal JJ cord-006870-f5w6fw6q 1913 18 artery artery NN cord-006870-f5w6fw6q 1913 19 near near IN cord-006870-f5w6fw6q 1913 20 to to TO cord-006870-f5w6fw6q 1913 21 complete complete JJ cord-006870-f5w6fw6q 1913 22 occlusion occlusion NN cord-006870-f5w6fw6q 1913 23 , , , cord-006870-f5w6fw6q 1913 24 even even RB cord-006870-f5w6fw6q 1913 25 beyond beyond IN cord-006870-f5w6fw6q 1913 26 usual usual JJ cord-006870-f5w6fw6q 1913 27 6 6 CD cord-006870-f5w6fw6q 1913 28 to to TO cord-006870-f5w6fw6q 1913 29 8 8 CD cord-006870-f5w6fw6q 1913 30 hours hour NNS cord-006870-f5w6fw6q 1913 31 time time NN cord-006870-f5w6fw6q 1913 32 window window NN cord-006870-f5w6fw6q 1913 33 for for IN cord-006870-f5w6fw6q 1913 34 EVT evt NN cord-006870-f5w6fw6q 1913 35 . . . cord-006870-f5w6fw6q 1914 1 Jugular jugular NN cord-006870-f5w6fw6q 1914 2 bulb bulb NN cord-006870-f5w6fw6q 1914 3 venous venous JJ cord-006870-f5w6fw6q 1914 4 monitoring monitoring NN cord-006870-f5w6fw6q 1914 5 can can MD cord-006870-f5w6fw6q 1914 6 provide provide VB cord-006870-f5w6fw6q 1914 7 information information NN cord-006870-f5w6fw6q 1914 8 about about IN cord-006870-f5w6fw6q 1914 9 cerebral cerebral JJ cord-006870-f5w6fw6q 1914 10 hemodynamics hemodynamic NNS cord-006870-f5w6fw6q 1914 11 and and CC cord-006870-f5w6fw6q 1914 12 metabolism metabolism NN cord-006870-f5w6fw6q 1914 13 . . . cord-006870-f5w6fw6q 1915 1 We -PRON- PRP cord-006870-f5w6fw6q 1915 2 investigated investigate VBD cord-006870-f5w6fw6q 1915 3 the the DT cord-006870-f5w6fw6q 1915 4 feasibility feasibility NN cord-006870-f5w6fw6q 1915 5 and and CC cord-006870-f5w6fw6q 1915 6 clinical clinical JJ cord-006870-f5w6fw6q 1915 7 application application NN cord-006870-f5w6fw6q 1915 8 of of IN cord-006870-f5w6fw6q 1915 9 jugular jugular NN cord-006870-f5w6fw6q 1915 10 bulb bulb NN cord-006870-f5w6fw6q 1915 11 venous venous JJ cord-006870-f5w6fw6q 1915 12 monitoring monitoring NN cord-006870-f5w6fw6q 1915 13 in in IN cord-006870-f5w6fw6q 1915 14 acute acute JJ cord-006870-f5w6fw6q 1915 15 ischemic ischemic JJ cord-006870-f5w6fw6q 1915 16 stroke stroke NN cord-006870-f5w6fw6q 1915 17 patients patient NNS cord-006870-f5w6fw6q 1915 18 at at IN cord-006870-f5w6fw6q 1915 19 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1915 20 care care NNP cord-006870-f5w6fw6q 1915 21 unit unit NN cord-006870-f5w6fw6q 1915 22 . . . cord-006870-f5w6fw6q 1916 1 From from IN cord-006870-f5w6fw6q 1916 2 March March NNP cord-006870-f5w6fw6q 1916 3 2015 2015 CD cord-006870-f5w6fw6q 1916 4 to to IN cord-006870-f5w6fw6q 1916 5 June June NNP cord-006870-f5w6fw6q 1916 6 2017 2017 CD cord-006870-f5w6fw6q 1916 7 , , , cord-006870-f5w6fw6q 1916 8 we -PRON- PRP cord-006870-f5w6fw6q 1916 9 conducted conduct VBD cord-006870-f5w6fw6q 1916 10 jugular jugular NN cord-006870-f5w6fw6q 1916 11 bulb bulb NN cord-006870-f5w6fw6q 1916 12 venous venous JJ cord-006870-f5w6fw6q 1916 13 monitoring monitoring NN cord-006870-f5w6fw6q 1916 14 in in IN cord-006870-f5w6fw6q 1916 15 33 33 CD cord-006870-f5w6fw6q 1916 16 patients patient NNS cord-006870-f5w6fw6q 1916 17 in in IN cord-006870-f5w6fw6q 1916 18 a a DT cord-006870-f5w6fw6q 1916 19 tertiary tertiary JJ cord-006870-f5w6fw6q 1916 20 referral referral JJ cord-006870-f5w6fw6q 1916 21 hospital hospital NN cord-006870-f5w6fw6q 1916 22 . . . cord-006870-f5w6fw6q 1917 1 Five five CD cord-006870-f5w6fw6q 1917 2 patients patient NNS cord-006870-f5w6fw6q 1917 3 were be VBD cord-006870-f5w6fw6q 1917 4 excluded exclude VBN cord-006870-f5w6fw6q 1917 5 ; ; : cord-006870-f5w6fw6q 1917 6 3 3 CD cord-006870-f5w6fw6q 1917 7 without without IN cord-006870-f5w6fw6q 1917 8 ventilator ventilator NN cord-006870-f5w6fw6q 1917 9 care care NN cord-006870-f5w6fw6q 1917 10 and and CC cord-006870-f5w6fw6q 1917 11 2 2 CD cord-006870-f5w6fw6q 1917 12 other other JJ cord-006870-f5w6fw6q 1917 13 diseases disease NNS cord-006870-f5w6fw6q 1917 14 than than IN cord-006870-f5w6fw6q 1917 15 stroke stroke NN cord-006870-f5w6fw6q 1917 16 . . . cord-006870-f5w6fw6q 1918 1 Jugular jugular NN cord-006870-f5w6fw6q 1918 2 venous venous JJ cord-006870-f5w6fw6q 1918 3 catheters catheter NNS cord-006870-f5w6fw6q 1918 4 were be VBD cord-006870-f5w6fw6q 1918 5 placed place VBN cord-006870-f5w6fw6q 1918 6 in in IN cord-006870-f5w6fw6q 1918 7 internal internal JJ cord-006870-f5w6fw6q 1918 8 jugular jugular NN cord-006870-f5w6fw6q 1918 9 vein vein NN cord-006870-f5w6fw6q 1918 10 by by IN cord-006870-f5w6fw6q 1918 11 ultrasound ultrasound NN cord-006870-f5w6fw6q 1918 12 - - HYPH cord-006870-f5w6fw6q 1918 13 guided guide VBN cord-006870-f5w6fw6q 1918 14 method method NN cord-006870-f5w6fw6q 1918 15 . . . cord-006870-f5w6fw6q 1919 1 Lactate lactate NN cord-006870-f5w6fw6q 1919 2 , , , cord-006870-f5w6fw6q 1919 3 venous venous JJ cord-006870-f5w6fw6q 1919 4 oxygen oxygen NN cord-006870-f5w6fw6q 1919 5 saturation saturation NN cord-006870-f5w6fw6q 1919 6 ( ( -LRB- cord-006870-f5w6fw6q 1919 7 SjvO2 SjvO2 NNP cord-006870-f5w6fw6q 1919 8 ) ) -RRB- cord-006870-f5w6fw6q 1919 9 , , , cord-006870-f5w6fw6q 1919 10 and and CC cord-006870-f5w6fw6q 1919 11 arteriovenous arteriovenous JJ cord-006870-f5w6fw6q 1919 12 oxygen oxygen NN cord-006870-f5w6fw6q 1919 13 saturation saturation NN cord-006870-f5w6fw6q 1919 14 differnece differnece NN cord-006870-f5w6fw6q 1919 15 ( ( -LRB- cord-006870-f5w6fw6q 1919 16 AVDO2 AVDO2 NNP cord-006870-f5w6fw6q 1919 17 ) ) -RRB- cord-006870-f5w6fw6q 1919 18 were be VBD cord-006870-f5w6fw6q 1919 19 monitored monitor VBN cord-006870-f5w6fw6q 1919 20 every every DT cord-006870-f5w6fw6q 1919 21 4 4 CD cord-006870-f5w6fw6q 1919 22 hours hour NNS cord-006870-f5w6fw6q 1919 23 . . . cord-006870-f5w6fw6q 1920 1 Metabolic metabolic JJ cord-006870-f5w6fw6q 1920 2 derangement derangement NN cord-006870-f5w6fw6q 1920 3 was be VBD cord-006870-f5w6fw6q 1920 4 defined define VBN cord-006870-f5w6fw6q 1920 5 when when WRB cord-006870-f5w6fw6q 1920 6 lactate lactate NN cord-006870-f5w6fw6q 1920 7 level level NN cord-006870-f5w6fw6q 1920 8 was be VBD cord-006870-f5w6fw6q 1920 9 more more JJR cord-006870-f5w6fw6q 1920 10 than than IN cord-006870-f5w6fw6q 1920 11 2.0 2.0 CD cord-006870-f5w6fw6q 1920 12 mmol mmol NN cord-006870-f5w6fw6q 1920 13 / / SYM cord-006870-f5w6fw6q 1920 14 l l NN cord-006870-f5w6fw6q 1920 15 . . . cord-006870-f5w6fw6q 1921 1 Patients patient NNS cord-006870-f5w6fw6q 1921 2 were be VBD cord-006870-f5w6fw6q 1921 3 divided divide VBN cord-006870-f5w6fw6q 1921 4 according accord VBG cord-006870-f5w6fw6q 1921 5 to to IN cord-006870-f5w6fw6q 1921 6 presence presence NN cord-006870-f5w6fw6q 1921 7 of of IN cord-006870-f5w6fw6q 1921 8 clinical clinical JJ cord-006870-f5w6fw6q 1921 9 deterioration deterioration NN cord-006870-f5w6fw6q 1921 10 . . . cord-006870-f5w6fw6q 1922 1 For for IN cord-006870-f5w6fw6q 1922 2 long long JJ cord-006870-f5w6fw6q 1922 3 - - HYPH cord-006870-f5w6fw6q 1922 4 term term NN cord-006870-f5w6fw6q 1922 5 prognosis prognosis NN cord-006870-f5w6fw6q 1922 6 , , , cord-006870-f5w6fw6q 1922 7 modified modify VBN cord-006870-f5w6fw6q 1922 8 Rankin Rankin NNP cord-006870-f5w6fw6q 1922 9 Scale Scale NNP cord-006870-f5w6fw6q 1922 10 5 5 CD cord-006870-f5w6fw6q 1922 11 - - SYM cord-006870-f5w6fw6q 1922 12 6 6 CD cord-006870-f5w6fw6q 1922 13 at at IN cord-006870-f5w6fw6q 1922 14 3 3 CD cord-006870-f5w6fw6q 1922 15 months month NNS cord-006870-f5w6fw6q 1922 16 were be VBD cord-006870-f5w6fw6q 1922 17 defined define VBN cord-006870-f5w6fw6q 1922 18 as as IN cord-006870-f5w6fw6q 1922 19 poor poor JJ cord-006870-f5w6fw6q 1922 20 outcome outcome NN cord-006870-f5w6fw6q 1922 21 . . . cord-006870-f5w6fw6q 1923 1 Twelve twelve CD cord-006870-f5w6fw6q 1923 2 patients patient NNS cord-006870-f5w6fw6q 1923 3 ( ( -LRB- cord-006870-f5w6fw6q 1923 4 42.9 42.9 CD cord-006870-f5w6fw6q 1923 5 % % NN cord-006870-f5w6fw6q 1923 6 ) ) -RRB- cord-006870-f5w6fw6q 1923 7 showed show VBD cord-006870-f5w6fw6q 1923 8 metabolic metabolic JJ cord-006870-f5w6fw6q 1923 9 derangement derangement NN cord-006870-f5w6fw6q 1923 10 and and CC cord-006870-f5w6fw6q 1923 11 they -PRON- PRP cord-006870-f5w6fw6q 1923 12 experienced experience VBD cord-006870-f5w6fw6q 1923 13 more more RBR cord-006870-f5w6fw6q 1923 14 frequent frequent JJ cord-006870-f5w6fw6q 1923 15 clinical clinical JJ cord-006870-f5w6fw6q 1923 16 deteriorations deterioration NNS cord-006870-f5w6fw6q 1923 17 compared compare VBN cord-006870-f5w6fw6q 1923 18 to to IN cord-006870-f5w6fw6q 1923 19 patients patient NNS cord-006870-f5w6fw6q 1923 20 without without IN cord-006870-f5w6fw6q 1923 21 metabolic metabolic JJ cord-006870-f5w6fw6q 1923 22 derangement derangement NN cord-006870-f5w6fw6q 1923 23 ( ( -LRB- cord-006870-f5w6fw6q 1923 24 n=9 n=9 NN cord-006870-f5w6fw6q 1923 25 , , , cord-006870-f5w6fw6q 1923 26 64.3 64.3 CD cord-006870-f5w6fw6q 1923 27 % % NN cord-006870-f5w6fw6q 1923 28 vs. vs. IN cord-006870-f5w6fw6q 1923 29 n=3 n=3 NN cord-006870-f5w6fw6q 1923 30 , , , cord-006870-f5w6fw6q 1923 31 21.4 21.4 CD cord-006870-f5w6fw6q 1923 32 % % NN cord-006870-f5w6fw6q 1923 33 , , , cord-006870-f5w6fw6q 1923 34 p=0.022 p=0.022 NNP cord-006870-f5w6fw6q 1923 35 ) ) -RRB- cord-006870-f5w6fw6q 1923 36 . . . cord-006870-f5w6fw6q 1924 1 Clinical clinical JJ cord-006870-f5w6fw6q 1924 2 deterioration deterioration NN cord-006870-f5w6fw6q 1924 3 was be VBD cord-006870-f5w6fw6q 1924 4 noted note VBN cord-006870-f5w6fw6q 1924 5 in in IN cord-006870-f5w6fw6q 1924 6 14 14 CD cord-006870-f5w6fw6q 1924 7 patients patient NNS cord-006870-f5w6fw6q 1924 8 , , , cord-006870-f5w6fw6q 1924 9 and and CC cord-006870-f5w6fw6q 1924 10 lactate lactate NN cord-006870-f5w6fw6q 1924 11 level level NN cord-006870-f5w6fw6q 1924 12 was be VBD cord-006870-f5w6fw6q 1924 13 significantly significantly RB cord-006870-f5w6fw6q 1924 14 higher high JJR cord-006870-f5w6fw6q 1924 15 in in IN cord-006870-f5w6fw6q 1924 16 the the DT cord-006870-f5w6fw6q 1924 17 presence presence NN cord-006870-f5w6fw6q 1924 18 of of IN cord-006870-f5w6fw6q 1924 19 clinical clinical JJ cord-006870-f5w6fw6q 1924 20 deterioration deterioration NN cord-006870-f5w6fw6q 1924 21 group group NN cord-006870-f5w6fw6q 1924 22 ( ( -LRB- cord-006870-f5w6fw6q 1924 23 1.44±0.48 1.44±0.48 CD cord-006870-f5w6fw6q 1924 24 vs. vs. FW cord-006870-f5w6fw6q 1924 25 1.04±0.20mmol 1.04±0.20mmol CD cord-006870-f5w6fw6q 1924 26 / / SYM cord-006870-f5w6fw6q 1924 27 l l NN cord-006870-f5w6fw6q 1924 28 , , , cord-006870-f5w6fw6q 1924 29 p=0.009 p=0.009 NNP cord-006870-f5w6fw6q 1924 30 ) ) -RRB- cord-006870-f5w6fw6q 1924 31 . . . cord-006870-f5w6fw6q 1925 1 Adjusting adjust VBG cord-006870-f5w6fw6q 1925 2 other other JJ cord-006870-f5w6fw6q 1925 3 potential potential JJ cord-006870-f5w6fw6q 1925 4 variables variable NNS cord-006870-f5w6fw6q 1925 5 ( ( -LRB- cord-006870-f5w6fw6q 1925 6 age age NN cord-006870-f5w6fw6q 1925 7 , , , cord-006870-f5w6fw6q 1925 8 baseline baseline JJ cord-006870-f5w6fw6q 1925 9 stroke stroke NN cord-006870-f5w6fw6q 1925 10 severity severity NN cord-006870-f5w6fw6q 1925 11 , , , cord-006870-f5w6fw6q 1925 12 SjvO2 SjvO2 NNP cord-006870-f5w6fw6q 1925 13 , , , cord-006870-f5w6fw6q 1925 14 and and CC cord-006870-f5w6fw6q 1925 15 AVDO2 AVDO2 NNP cord-006870-f5w6fw6q 1925 16 ) ) -RRB- cord-006870-f5w6fw6q 1925 17 , , , cord-006870-f5w6fw6q 1925 18 metabolic metabolic JJ cord-006870-f5w6fw6q 1925 19 derangement derangement NN cord-006870-f5w6fw6q 1925 20 was be VBD cord-006870-f5w6fw6q 1925 21 an an DT cord-006870-f5w6fw6q 1925 22 independent independent JJ cord-006870-f5w6fw6q 1925 23 factor factor NN cord-006870-f5w6fw6q 1925 24 associated associate VBN cord-006870-f5w6fw6q 1925 25 with with IN cord-006870-f5w6fw6q 1925 26 clinical clinical JJ cord-006870-f5w6fw6q 1925 27 deterioration deterioration NN cord-006870-f5w6fw6q 1925 28 ( ( -LRB- cord-006870-f5w6fw6q 1925 29 OR or CC cord-006870-f5w6fw6q 1925 30 6.60 6.60 CD cord-006870-f5w6fw6q 1925 31 , , , cord-006870-f5w6fw6q 1925 32 95 95 CD cord-006870-f5w6fw6q 1925 33 % % NN cord-006870-f5w6fw6q 1925 34 CI CI NNP cord-006870-f5w6fw6q 1925 35 1.23 1.23 CD cord-006870-f5w6fw6q 1925 36 - - SYM cord-006870-f5w6fw6q 1925 37 35.44 35.44 CD cord-006870-f5w6fw6q 1925 38 , , , cord-006870-f5w6fw6q 1925 39 p=0.028 p=0.028 NN cord-006870-f5w6fw6q 1925 40 ) ) -RRB- cord-006870-f5w6fw6q 1925 41 . . . cord-006870-f5w6fw6q 1926 1 Meanwhile meanwhile RB cord-006870-f5w6fw6q 1926 2 , , , cord-006870-f5w6fw6q 1926 3 poor poor JJ cord-006870-f5w6fw6q 1926 4 outcome outcome NN cord-006870-f5w6fw6q 1926 5 group group NN cord-006870-f5w6fw6q 1926 6 ( ( -LRB- cord-006870-f5w6fw6q 1926 7 n=12 n=12 NNP cord-006870-f5w6fw6q 1926 8 ) ) -RRB- cord-006870-f5w6fw6q 1926 9 showed show VBD cord-006870-f5w6fw6q 1926 10 no no DT cord-006870-f5w6fw6q 1926 11 difference difference NN cord-006870-f5w6fw6q 1926 12 on on IN cord-006870-f5w6fw6q 1926 13 lactate lactate NN cord-006870-f5w6fw6q 1926 14 level level NN cord-006870-f5w6fw6q 1926 15 , , , cord-006870-f5w6fw6q 1926 16 but but CC cord-006870-f5w6fw6q 1926 17 AVDO2 AVDO2 NNS cord-006870-f5w6fw6q 1926 18 were be VBD cord-006870-f5w6fw6q 1926 19 higher high JJR cord-006870-f5w6fw6q 1926 20 in in IN cord-006870-f5w6fw6q 1926 21 poor poor JJ cord-006870-f5w6fw6q 1926 22 outcome outcome NN cord-006870-f5w6fw6q 1926 23 group group NN cord-006870-f5w6fw6q 1926 24 ( ( -LRB- cord-006870-f5w6fw6q 1926 25 29.54±5.51 29.54±5.51 CD cord-006870-f5w6fw6q 1926 26 v. v. CC cord-006870-f5w6fw6q 1926 27 24.95±5.65 24.95±5.65 CD cord-006870-f5w6fw6q 1926 28 , , , cord-006870-f5w6fw6q 1926 29 p=0.041 p=0.041 NNP cord-006870-f5w6fw6q 1926 30 ) ) -RRB- cord-006870-f5w6fw6q 1926 31 . . . cord-006870-f5w6fw6q 1927 1 AVDO2 AVDO2 NNP cord-006870-f5w6fw6q 1927 2 remained remain VBD cord-006870-f5w6fw6q 1927 3 an an DT cord-006870-f5w6fw6q 1927 4 independent independent JJ cord-006870-f5w6fw6q 1927 5 factor factor NN cord-006870-f5w6fw6q 1927 6 for for IN cord-006870-f5w6fw6q 1927 7 poor poor JJ cord-006870-f5w6fw6q 1927 8 outcome outcome NN cord-006870-f5w6fw6q 1927 9 after after IN cord-006870-f5w6fw6q 1927 10 multivariable multivariable JJ cord-006870-f5w6fw6q 1927 11 logistic logistic JJ cord-006870-f5w6fw6q 1927 12 regression regression NN cord-006870-f5w6fw6q 1927 13 analysis analysis NN cord-006870-f5w6fw6q 1927 14 ( ( -LRB- cord-006870-f5w6fw6q 1927 15 OR or CC cord-006870-f5w6fw6q 1927 16 3.68 3.68 CD cord-006870-f5w6fw6q 1927 17 , , , cord-006870-f5w6fw6q 1927 18 95 95 CD cord-006870-f5w6fw6q 1927 19 % % NN cord-006870-f5w6fw6q 1927 20 CI CI NNP cord-006870-f5w6fw6q 1927 21 1.08 1.08 CD cord-006870-f5w6fw6q 1927 22 - - SYM cord-006870-f5w6fw6q 1927 23 12.55 12.55 CD cord-006870-f5w6fw6q 1927 24 , , , cord-006870-f5w6fw6q 1927 25 p=0.038 p=0.038 NNP cord-006870-f5w6fw6q 1927 26 ) ) -RRB- cord-006870-f5w6fw6q 1927 27 . . . cord-006870-f5w6fw6q 1928 1 This this DT cord-006870-f5w6fw6q 1928 2 study study NN cord-006870-f5w6fw6q 1928 3 showed show VBD cord-006870-f5w6fw6q 1928 4 that that IN cord-006870-f5w6fw6q 1928 5 lactate lactate NN cord-006870-f5w6fw6q 1928 6 was be VBD cord-006870-f5w6fw6q 1928 7 associated associate VBN cord-006870-f5w6fw6q 1928 8 with with IN cord-006870-f5w6fw6q 1928 9 clinical clinical JJ cord-006870-f5w6fw6q 1928 10 deterioration deterioration NN cord-006870-f5w6fw6q 1928 11 during during IN cord-006870-f5w6fw6q 1928 12 neurocritical neurocritical JJ cord-006870-f5w6fw6q 1928 13 care care NN cord-006870-f5w6fw6q 1928 14 , , , cord-006870-f5w6fw6q 1928 15 whereas whereas IN cord-006870-f5w6fw6q 1928 16 venous venous JJ cord-006870-f5w6fw6q 1928 17 desaturation desaturation NN cord-006870-f5w6fw6q 1928 18 contributed contribute VBD cord-006870-f5w6fw6q 1928 19 to to IN cord-006870-f5w6fw6q 1928 20 long long JJ cord-006870-f5w6fw6q 1928 21 - - HYPH cord-006870-f5w6fw6q 1928 22 term term NN cord-006870-f5w6fw6q 1928 23 prognosis prognosis NN cord-006870-f5w6fw6q 1928 24 . . . cord-006870-f5w6fw6q 1929 1 Jugular jugular NN cord-006870-f5w6fw6q 1929 2 bulb bulb NN cord-006870-f5w6fw6q 1929 3 venous venous JJ cord-006870-f5w6fw6q 1929 4 monitoring monitoring NN cord-006870-f5w6fw6q 1929 5 is be VBZ cord-006870-f5w6fw6q 1929 6 a a DT cord-006870-f5w6fw6q 1929 7 feasible feasible JJ cord-006870-f5w6fw6q 1929 8 tool tool NN cord-006870-f5w6fw6q 1929 9 in in IN cord-006870-f5w6fw6q 1929 10 patients patient NNS cord-006870-f5w6fw6q 1929 11 with with IN cord-006870-f5w6fw6q 1929 12 acute acute JJ cord-006870-f5w6fw6q 1929 13 ischemic ischemic JJ cord-006870-f5w6fw6q 1929 14 stroke stroke NN cord-006870-f5w6fw6q 1929 15 at at IN cord-006870-f5w6fw6q 1929 16 neurocritical neurocritical NNP cord-006870-f5w6fw6q 1929 17 care care NNP cord-006870-f5w6fw6q 1929 18 unit unit NN cord-006870-f5w6fw6q 1929 19 . . . cord-006870-f5w6fw6q 1930 1 Swift swift JJ cord-006870-f5w6fw6q 1930 2 recognition recognition NN cord-006870-f5w6fw6q 1930 3 of of IN cord-006870-f5w6fw6q 1930 4 stroke stroke NN cord-006870-f5w6fw6q 1930 5 symptoms symptom NNS cord-006870-f5w6fw6q 1930 6 , , , cord-006870-f5w6fw6q 1930 7 immediate immediate JJ cord-006870-f5w6fw6q 1930 8 access access NN cord-006870-f5w6fw6q 1930 9 to to IN cord-006870-f5w6fw6q 1930 10 testing test VBG cord-006870-f5w6fw6q 1930 11 and and CC cord-006870-f5w6fw6q 1930 12 timely timely JJ cord-006870-f5w6fw6q 1930 13 treatment treatment NN cord-006870-f5w6fw6q 1930 14 plays play VBZ cord-006870-f5w6fw6q 1930 15 a a DT cord-006870-f5w6fw6q 1930 16 vital vital JJ cord-006870-f5w6fw6q 1930 17 role role NN cord-006870-f5w6fw6q 1930 18 in in IN cord-006870-f5w6fw6q 1930 19 functional functional JJ cord-006870-f5w6fw6q 1930 20 outcomes outcome NNS cord-006870-f5w6fw6q 1930 21 ( ( -LRB- cord-006870-f5w6fw6q 1930 22 Middleton Middleton NNP cord-006870-f5w6fw6q 1930 23 et et NNP cord-006870-f5w6fw6q 1930 24 al al NNP cord-006870-f5w6fw6q 1930 25 . . NNP cord-006870-f5w6fw6q 1930 26 , , , cord-006870-f5w6fw6q 1930 27 2015 2015 CD cord-006870-f5w6fw6q 1930 28 ) ) -RRB- cord-006870-f5w6fw6q 1930 29 . . . cord-006870-f5w6fw6q 1931 1 Delays delay NNS cord-006870-f5w6fw6q 1931 2 can can MD cord-006870-f5w6fw6q 1931 3 postpone postpone VB cord-006870-f5w6fw6q 1931 4 treatment treatment NN cord-006870-f5w6fw6q 1931 5 and and CC cord-006870-f5w6fw6q 1931 6 complicate complicate VB cord-006870-f5w6fw6q 1931 7 recovery recovery NN cord-006870-f5w6fw6q 1931 8 . . . cord-006870-f5w6fw6q 1932 1 Delays delay NNS cord-006870-f5w6fw6q 1932 2 at at IN cord-006870-f5w6fw6q 1932 3 this this DT cord-006870-f5w6fw6q 1932 4 facility facility NN cord-006870-f5w6fw6q 1932 5 included include VBD cord-006870-f5w6fw6q 1932 6 registration registration NN cord-006870-f5w6fw6q 1932 7 , , , cord-006870-f5w6fw6q 1932 8 order order NN cord-006870-f5w6fw6q 1932 9 entry entry NN cord-006870-f5w6fw6q 1932 10 times time NNS cord-006870-f5w6fw6q 1932 11 , , , cord-006870-f5w6fw6q 1932 12 and and CC cord-006870-f5w6fw6q 1932 13 imaging imaging NN cord-006870-f5w6fw6q 1932 14 . . . cord-006870-f5w6fw6q 1933 1 PI PI NNP cord-006870-f5w6fw6q 1933 2 included include VBD cord-006870-f5w6fw6q 1933 3 evaluating evaluate VBG cord-006870-f5w6fw6q 1933 4 and and CC cord-006870-f5w6fw6q 1933 5 eliminating eliminate VBG cord-006870-f5w6fw6q 1933 6 interruptions interruption NNS cord-006870-f5w6fw6q 1933 7 , , , cord-006870-f5w6fw6q 1933 8 with with IN cord-006870-f5w6fw6q 1933 9 a a DT cord-006870-f5w6fw6q 1933 10 goal goal NN cord-006870-f5w6fw6q 1933 11 of of IN cord-006870-f5w6fw6q 1933 12 reducing reduce VBG cord-006870-f5w6fw6q 1933 13 the the DT cord-006870-f5w6fw6q 1933 14 time time NN cord-006870-f5w6fw6q 1933 15 to to IN cord-006870-f5w6fw6q 1933 16 treatment treatment NN cord-006870-f5w6fw6q 1933 17 . . . cord-006870-f5w6fw6q 1934 1 Process process NN cord-006870-f5w6fw6q 1934 2 Improvement improvement NN cord-006870-f5w6fw6q 1934 3 ( ( -LRB- cord-006870-f5w6fw6q 1934 4 PI PI NNP cord-006870-f5w6fw6q 1934 5 ) ) -RRB- cord-006870-f5w6fw6q 1934 6 utilized utilize VBD cord-006870-f5w6fw6q 1934 7 an an DT cord-006870-f5w6fw6q 1934 8 evidence evidence NN cord-006870-f5w6fw6q 1934 9 - - HYPH cord-006870-f5w6fw6q 1934 10 based base VBN cord-006870-f5w6fw6q 1934 11 algorithm algorithm NN cord-006870-f5w6fw6q 1934 12 to to TO cord-006870-f5w6fw6q 1934 13 improve improve VB cord-006870-f5w6fw6q 1934 14 performance performance NN cord-006870-f5w6fw6q 1934 15 metrics metric NNS cord-006870-f5w6fw6q 1934 16 and and CC cord-006870-f5w6fw6q 1934 17 treatment treatment NN cord-006870-f5w6fw6q 1934 18 of of IN cord-006870-f5w6fw6q 1934 19 acute acute JJ cord-006870-f5w6fw6q 1934 20 strokes stroke NNS cord-006870-f5w6fw6q 1934 21 . . . cord-006870-f5w6fw6q 1935 1 Setting set VBG cord-006870-f5w6fw6q 1935 2 was be VBD cord-006870-f5w6fw6q 1935 3 a a DT cord-006870-f5w6fw6q 1935 4 suburban suburban JJ cord-006870-f5w6fw6q 1935 5 , , , cord-006870-f5w6fw6q 1935 6 ANCC ANCC NNP cord-006870-f5w6fw6q 1935 7 Magnet Magnet NNP cord-006870-f5w6fw6q 1935 8 recognized recognize VBD cord-006870-f5w6fw6q 1935 9 primary primary JJ cord-006870-f5w6fw6q 1935 10 stroke stroke NN cord-006870-f5w6fw6q 1935 11 center center NN cord-006870-f5w6fw6q 1935 12 with with IN cord-006870-f5w6fw6q 1935 13 16 16 CD cord-006870-f5w6fw6q 1935 14 beds bed NNS cord-006870-f5w6fw6q 1935 15 in in IN cord-006870-f5w6fw6q 1935 16 the the DT cord-006870-f5w6fw6q 1935 17 ED ED NNP cord-006870-f5w6fw6q 1935 18 that that WDT cord-006870-f5w6fw6q 1935 19 experiences experience VBZ cord-006870-f5w6fw6q 1935 20 24,010 24,010 CD cord-006870-f5w6fw6q 1935 21 ED ED NNP cord-006870-f5w6fw6q 1935 22 visits visit NNS cord-006870-f5w6fw6q 1935 23 and and CC cord-006870-f5w6fw6q 1935 24 6,619 6,619 CD cord-006870-f5w6fw6q 1935 25 admissions admission NNS cord-006870-f5w6fw6q 1935 26 per per IN cord-006870-f5w6fw6q 1935 27 year year NN cord-006870-f5w6fw6q 1935 28 . . . cord-006870-f5w6fw6q 1936 1 Patients patient NNS cord-006870-f5w6fw6q 1936 2 included include VBN cord-006870-f5w6fw6q 1936 3 in in IN cord-006870-f5w6fw6q 1936 4 the the DT cord-006870-f5w6fw6q 1936 5 acute acute JJ cord-006870-f5w6fw6q 1936 6 stroke stroke NN cord-006870-f5w6fw6q 1936 7 protocol protocol NN cord-006870-f5w6fw6q 1936 8 presented present VBN cord-006870-f5w6fw6q 1936 9 with with IN cord-006870-f5w6fw6q 1936 10 signs sign NNS cord-006870-f5w6fw6q 1936 11 and and CC cord-006870-f5w6fw6q 1936 12 symptoms symptom NNS cord-006870-f5w6fw6q 1936 13 of of IN cord-006870-f5w6fw6q 1936 14 stroke stroke NN cord-006870-f5w6fw6q 1936 15 and and CC cord-006870-f5w6fw6q 1936 16 last last JJ cord-006870-f5w6fw6q 1936 17 known know VBN cord-006870-f5w6fw6q 1936 18 well well RB cord-006870-f5w6fw6q 1936 19 within within IN cord-006870-f5w6fw6q 1936 20 12 12 CD cord-006870-f5w6fw6q 1936 21 hours hour NNS cord-006870-f5w6fw6q 1936 22 of of IN cord-006870-f5w6fw6q 1936 23 symptom symptom NN cord-006870-f5w6fw6q 1936 24 onset onset NN cord-006870-f5w6fw6q 1936 25 . . . cord-006870-f5w6fw6q 1937 1 Participation participation NN cord-006870-f5w6fw6q 1937 2 included include VBD cord-006870-f5w6fw6q 1937 3 ED ED NNP cord-006870-f5w6fw6q 1937 4 staff staff NN cord-006870-f5w6fw6q 1937 5 , , , cord-006870-f5w6fw6q 1937 6 and and CC cord-006870-f5w6fw6q 1937 7 staff staff NN cord-006870-f5w6fw6q 1937 8 working work VBG cord-006870-f5w6fw6q 1937 9 in in IN cord-006870-f5w6fw6q 1937 10 areas area NNS cord-006870-f5w6fw6q 1937 11 impacted impact VBN cord-006870-f5w6fw6q 1937 12 by by IN cord-006870-f5w6fw6q 1937 13 stroke stroke NN cord-006870-f5w6fw6q 1937 14 care care NN cord-006870-f5w6fw6q 1937 15 . . . cord-006870-f5w6fw6q 1938 1 Code Code NNP cord-006870-f5w6fw6q 1938 2 Stroke Stroke NNP cord-006870-f5w6fw6q 1938 3 was be VBD cord-006870-f5w6fw6q 1938 4 initiated initiate VBN cord-006870-f5w6fw6q 1938 5 for for IN cord-006870-f5w6fw6q 1938 6 patients patient NNS cord-006870-f5w6fw6q 1938 7 who who WP cord-006870-f5w6fw6q 1938 8 fit fit VBP cord-006870-f5w6fw6q 1938 9 the the DT cord-006870-f5w6fw6q 1938 10 criteria criterion NNS cord-006870-f5w6fw6q 1938 11 . . . cord-006870-f5w6fw6q 1939 1 An an DT cord-006870-f5w6fw6q 1939 2 overhead overhead JJ cord-006870-f5w6fw6q 1939 3 page page NN cord-006870-f5w6fw6q 1939 4 was be VBD cord-006870-f5w6fw6q 1939 5 implemented implement VBN cord-006870-f5w6fw6q 1939 6 notifying notify VBG cord-006870-f5w6fw6q 1939 7 the the DT cord-006870-f5w6fw6q 1939 8 team team NN cord-006870-f5w6fw6q 1939 9 throughout throughout IN cord-006870-f5w6fw6q 1939 10 the the DT cord-006870-f5w6fw6q 1939 11 hospital hospital NN cord-006870-f5w6fw6q 1939 12 . . . cord-006870-f5w6fw6q 1940 1 Radiology radiology NN cord-006870-f5w6fw6q 1940 2 would would MD cord-006870-f5w6fw6q 1940 3 prioritize prioritize VB cord-006870-f5w6fw6q 1940 4 CT CT NNP cord-006870-f5w6fw6q 1940 5 and and CC cord-006870-f5w6fw6q 1940 6 call call VB cord-006870-f5w6fw6q 1940 7 the the DT cord-006870-f5w6fw6q 1940 8 ED ED NNP cord-006870-f5w6fw6q 1940 9 as as RB cord-006870-f5w6fw6q 1940 10 soon soon RB cord-006870-f5w6fw6q 1940 11 as as IN cord-006870-f5w6fw6q 1940 12 CT CT NNP cord-006870-f5w6fw6q 1940 13 was be VBD cord-006870-f5w6fw6q 1940 14 ready ready JJ cord-006870-f5w6fw6q 1940 15 . . . cord-006870-f5w6fw6q 1941 1 In in IN cord-006870-f5w6fw6q 1941 2 the the DT cord-006870-f5w6fw6q 1941 3 meantime meantime NN cord-006870-f5w6fw6q 1941 4 , , , cord-006870-f5w6fw6q 1941 5 ED ED NNP cord-006870-f5w6fw6q 1941 6 team team NN cord-006870-f5w6fw6q 1941 7 continued continue VBD cord-006870-f5w6fw6q 1941 8 assessments assessment NNS cord-006870-f5w6fw6q 1941 9 . . . cord-006870-f5w6fw6q 1942 1 With with IN cord-006870-f5w6fw6q 1942 2 CT CT NNP cord-006870-f5w6fw6q 1942 3 resulted result VBD cord-006870-f5w6fw6q 1942 4 , , , cord-006870-f5w6fw6q 1942 5 the the DT cord-006870-f5w6fw6q 1942 6 physician physician NN cord-006870-f5w6fw6q 1942 7 would would MD cord-006870-f5w6fw6q 1942 8 determine determine VB cord-006870-f5w6fw6q 1942 9 whether whether IN cord-006870-f5w6fw6q 1942 10 the the DT cord-006870-f5w6fw6q 1942 11 patient patient NN cord-006870-f5w6fw6q 1942 12 was be VBD cord-006870-f5w6fw6q 1942 13 eligible eligible JJ cord-006870-f5w6fw6q 1942 14 for for IN cord-006870-f5w6fw6q 1942 15 tPA tPA NNP cord-006870-f5w6fw6q 1942 16 . . . cord-006870-f5w6fw6q 1943 1 The the DT cord-006870-f5w6fw6q 1943 2 acute acute JJ cord-006870-f5w6fw6q 1943 3 stroke stroke NN cord-006870-f5w6fw6q 1943 4 protocol protocol NN cord-006870-f5w6fw6q 1943 5 included include VBD cord-006870-f5w6fw6q 1943 6 a a DT cord-006870-f5w6fw6q 1943 7 list list NN cord-006870-f5w6fw6q 1943 8 of of IN cord-006870-f5w6fw6q 1943 9 inclusion inclusion NN cord-006870-f5w6fw6q 1943 10 / / SYM cord-006870-f5w6fw6q 1943 11 exclusion exclusion NN cord-006870-f5w6fw6q 1943 12 criteria criterion NNS cord-006870-f5w6fw6q 1943 13 for for IN cord-006870-f5w6fw6q 1943 14 tPA tPA NNP cord-006870-f5w6fw6q 1943 15 administration administration NN cord-006870-f5w6fw6q 1943 16 . . . cord-006870-f5w6fw6q 1944 1 Other other JJ cord-006870-f5w6fw6q 1944 2 treatment treatment NN cord-006870-f5w6fw6q 1944 3 requirements requirement NNS cord-006870-f5w6fw6q 1944 4 included include VBD cord-006870-f5w6fw6q 1944 5 reminders reminder NNS cord-006870-f5w6fw6q 1944 6 for for IN cord-006870-f5w6fw6q 1944 7 frequency frequency NN cord-006870-f5w6fw6q 1944 8 of of IN cord-006870-f5w6fw6q 1944 9 vital vital JJ cord-006870-f5w6fw6q 1944 10 signs sign NNS cord-006870-f5w6fw6q 1944 11 , , , cord-006870-f5w6fw6q 1944 12 neuro neuro NNP cord-006870-f5w6fw6q 1944 13 checks check NNS cord-006870-f5w6fw6q 1944 14 and and CC cord-006870-f5w6fw6q 1944 15 assessments assessment NNS cord-006870-f5w6fw6q 1944 16 . . . cord-006870-f5w6fw6q 1945 1 Implementation implementation NN cord-006870-f5w6fw6q 1945 2 began begin VBD cord-006870-f5w6fw6q 1945 3 in in IN cord-006870-f5w6fw6q 1945 4 May May NNP cord-006870-f5w6fw6q 1945 5 2016 2016 CD cord-006870-f5w6fw6q 1945 6 and and CC cord-006870-f5w6fw6q 1945 7 the the DT cord-006870-f5w6fw6q 1945 8 team team NN cord-006870-f5w6fw6q 1945 9 began begin VBD cord-006870-f5w6fw6q 1945 10 to to TO cord-006870-f5w6fw6q 1945 11 see see VB cord-006870-f5w6fw6q 1945 12 a a DT cord-006870-f5w6fw6q 1945 13 significant significant JJ cord-006870-f5w6fw6q 1945 14 decrease decrease NN cord-006870-f5w6fw6q 1945 15 in in IN cord-006870-f5w6fw6q 1945 16 CT CT NNP cord-006870-f5w6fw6q 1945 17 times time NNS cord-006870-f5w6fw6q 1945 18 and and CC cord-006870-f5w6fw6q 1945 19 better well JJR cord-006870-f5w6fw6q 1945 20 compliance compliance NN cord-006870-f5w6fw6q 1945 21 of of IN cord-006870-f5w6fw6q 1945 22 dysphagia dysphagia NN cord-006870-f5w6fw6q 1945 23 screening screening NN cord-006870-f5w6fw6q 1945 24 and and CC cord-006870-f5w6fw6q 1945 25 NIH NIH NNP cord-006870-f5w6fw6q 1945 26 assessments assessment NNS cord-006870-f5w6fw6q 1945 27 . . . cord-006870-f5w6fw6q 1946 1 CT CT NNP cord-006870-f5w6fw6q 1946 2 TAT TAT NNP cord-006870-f5w6fw6q 1946 3 completed complete VBD cord-006870-f5w6fw6q 1946 4 within within IN cord-006870-f5w6fw6q 1946 5 45 45 CD cord-006870-f5w6fw6q 1946 6 minutes minute NNS cord-006870-f5w6fw6q 1946 7 increased increase VBD cord-006870-f5w6fw6q 1946 8 from from IN cord-006870-f5w6fw6q 1946 9 62 62 CD cord-006870-f5w6fw6q 1946 10 % % NN cord-006870-f5w6fw6q 1946 11 to to TO cord-006870-f5w6fw6q 1946 12 83 83 CD cord-006870-f5w6fw6q 1946 13 % % NN cord-006870-f5w6fw6q 1946 14 . . . cord-006870-f5w6fw6q 1947 1 NIH NIH NNP cord-006870-f5w6fw6q 1947 2 Stroke Stroke NNP cord-006870-f5w6fw6q 1947 3 Scale Scale NNP cord-006870-f5w6fw6q 1947 4 completion completion NN cord-006870-f5w6fw6q 1947 5 rose rise VBD cord-006870-f5w6fw6q 1947 6 from from IN cord-006870-f5w6fw6q 1947 7 79 79 CD cord-006870-f5w6fw6q 1947 8 % % NN cord-006870-f5w6fw6q 1947 9 to to TO cord-006870-f5w6fw6q 1947 10 100 100 CD cord-006870-f5w6fw6q 1947 11 % % NN cord-006870-f5w6fw6q 1947 12 . . . cord-006870-f5w6fw6q 1948 1 Compliance compliance NN cord-006870-f5w6fw6q 1948 2 with with IN cord-006870-f5w6fw6q 1948 3 completing complete VBG cord-006870-f5w6fw6q 1948 4 dysphasia dysphasia NN cord-006870-f5w6fw6q 1948 5 screening screening NN cord-006870-f5w6fw6q 1948 6 increased increase VBD cord-006870-f5w6fw6q 1948 7 from from IN cord-006870-f5w6fw6q 1948 8 86 86 CD cord-006870-f5w6fw6q 1948 9 % % NN cord-006870-f5w6fw6q 1948 10 to to IN cord-006870-f5w6fw6q 1948 11 93 93 CD cord-006870-f5w6fw6q 1948 12 % % NN cord-006870-f5w6fw6q 1948 13 . . . cord-006870-f5w6fw6q 1949 1 Results result NNS cord-006870-f5w6fw6q 1949 2 stem stem VBP cord-006870-f5w6fw6q 1949 3 from from IN cord-006870-f5w6fw6q 1949 4 a a DT cord-006870-f5w6fw6q 1949 5 commitment commitment NN cord-006870-f5w6fw6q 1949 6 to to IN cord-006870-f5w6fw6q 1949 7 excellence excellence NN cord-006870-f5w6fw6q 1949 8 from from IN cord-006870-f5w6fw6q 1949 9 the the DT cord-006870-f5w6fw6q 1949 10 entire entire JJ cord-006870-f5w6fw6q 1949 11 team team NN cord-006870-f5w6fw6q 1949 12 . . . cord-006870-f5w6fw6q 1950 1 PI PI NNP cord-006870-f5w6fw6q 1950 2 continues continue VBZ cord-006870-f5w6fw6q 1950 3 to to TO cord-006870-f5w6fw6q 1950 4 further further RB cord-006870-f5w6fw6q 1950 5 improve improve VB cord-006870-f5w6fw6q 1950 6 care care NN cord-006870-f5w6fw6q 1950 7 for for IN cord-006870-f5w6fw6q 1950 8 stroke stroke NN cord-006870-f5w6fw6q 1950 9 patients patient NNS cord-006870-f5w6fw6q 1950 10 . . . cord-006870-f5w6fw6q 1951 1 Induced induce VBN cord-006870-f5w6fw6q 1951 2 hypertensive hypertensive JJ cord-006870-f5w6fw6q 1951 3 therapy therapy NN cord-006870-f5w6fw6q 1951 4 ( ( -LRB- cord-006870-f5w6fw6q 1951 5 IHT IHT NNP cord-006870-f5w6fw6q 1951 6 ) ) -RRB- cord-006870-f5w6fw6q 1951 7 has have VBZ cord-006870-f5w6fw6q 1951 8 used use VBN cord-006870-f5w6fw6q 1951 9 to to TO cord-006870-f5w6fw6q 1951 10 enhance enhance VB cord-006870-f5w6fw6q 1951 11 cerebral cerebral JJ cord-006870-f5w6fw6q 1951 12 perfusion perfusion NN cord-006870-f5w6fw6q 1951 13 pressure pressure NN cord-006870-f5w6fw6q 1951 14 in in IN cord-006870-f5w6fw6q 1951 15 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 1951 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 1951 17 and and CC cord-006870-f5w6fw6q 1951 18 stroke stroke NN cord-006870-f5w6fw6q 1951 19 , , , cord-006870-f5w6fw6q 1951 20 but but CC cord-006870-f5w6fw6q 1951 21 there there EX cord-006870-f5w6fw6q 1951 22 is be VBZ cord-006870-f5w6fw6q 1951 23 no no DT cord-006870-f5w6fw6q 1951 24 established establish VBN cord-006870-f5w6fw6q 1951 25 indication indication NN cord-006870-f5w6fw6q 1951 26 for for IN cord-006870-f5w6fw6q 1951 27 IHT IHT NNP cord-006870-f5w6fw6q 1951 28 in in IN cord-006870-f5w6fw6q 1951 29 ischemic ischemic JJ cord-006870-f5w6fw6q 1951 30 stroke stroke NN cord-006870-f5w6fw6q 1951 31 . . . cord-006870-f5w6fw6q 1952 1 We -PRON- PRP cord-006870-f5w6fw6q 1952 2 report report VBP cord-006870-f5w6fw6q 1952 3 the the DT cord-006870-f5w6fw6q 1952 4 usage usage NN cord-006870-f5w6fw6q 1952 5 of of IN cord-006870-f5w6fw6q 1952 6 IHT IHT NNP cord-006870-f5w6fw6q 1952 7 in in IN cord-006870-f5w6fw6q 1952 8 acute acute JJ cord-006870-f5w6fw6q 1952 9 ischemic ischemic JJ cord-006870-f5w6fw6q 1952 10 patients patient NNS cord-006870-f5w6fw6q 1952 11 with with IN cord-006870-f5w6fw6q 1952 12 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 1952 13 instability instability NN cord-006870-f5w6fw6q 1952 14 caused cause VBN cord-006870-f5w6fw6q 1952 15 by by IN cord-006870-f5w6fw6q 1952 16 steno steno NN cord-006870-f5w6fw6q 1952 17 - - HYPH cord-006870-f5w6fw6q 1952 18 occlusive occlusive JJ cord-006870-f5w6fw6q 1952 19 disease disease NN cord-006870-f5w6fw6q 1952 20 of of IN cord-006870-f5w6fw6q 1952 21 a a DT cord-006870-f5w6fw6q 1952 22 main main JJ cord-006870-f5w6fw6q 1952 23 cerebral cerebral JJ cord-006870-f5w6fw6q 1952 24 artery artery NN cord-006870-f5w6fw6q 1952 25 . . . cord-006870-f5w6fw6q 1953 1 We -PRON- PRP cord-006870-f5w6fw6q 1953 2 reviewed review VBD cord-006870-f5w6fw6q 1953 3 acute acute JJ cord-006870-f5w6fw6q 1953 4 ischemic ischemic JJ cord-006870-f5w6fw6q 1953 5 stroke stroke NN cord-006870-f5w6fw6q 1953 6 patients patient NNS cord-006870-f5w6fw6q 1953 7 with with IN cord-006870-f5w6fw6q 1953 8 cerebral cerebral JJ cord-006870-f5w6fw6q 1953 9 perfusion perfusion NN cord-006870-f5w6fw6q 1953 10 deficit deficit NN cord-006870-f5w6fw6q 1953 11 due due JJ cord-006870-f5w6fw6q 1953 12 to to IN cord-006870-f5w6fw6q 1953 13 intracranial intracranial JJ cord-006870-f5w6fw6q 1953 14 and and CC cord-006870-f5w6fw6q 1953 15 extracranial extracranial JJ cord-006870-f5w6fw6q 1953 16 steno steno NN cord-006870-f5w6fw6q 1953 17 - - HYPH cord-006870-f5w6fw6q 1953 18 occlusive occlusive JJ cord-006870-f5w6fw6q 1953 19 disease disease NN cord-006870-f5w6fw6q 1953 20 . . . cord-006870-f5w6fw6q 1954 1 IHT IHT NNP cord-006870-f5w6fw6q 1954 2 was be VBD cord-006870-f5w6fw6q 1954 3 applied apply VBN cord-006870-f5w6fw6q 1954 4 for for IN cord-006870-f5w6fw6q 1954 5 early early JJ cord-006870-f5w6fw6q 1954 6 neurological neurological JJ cord-006870-f5w6fw6q 1954 7 deterioration deterioration NN cord-006870-f5w6fw6q 1954 8 and and CC cord-006870-f5w6fw6q 1954 9 maintained maintain VBN cord-006870-f5w6fw6q 1954 10 until until IN cord-006870-f5w6fw6q 1954 11 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 1954 12 instability instability NN cord-006870-f5w6fw6q 1954 13 was be VBD cord-006870-f5w6fw6q 1954 14 stabilized stabilize VBN cord-006870-f5w6fw6q 1954 15 over over IN cord-006870-f5w6fw6q 1954 16 24 24 CD cord-006870-f5w6fw6q 1954 17 hours hour NNS cord-006870-f5w6fw6q 1954 18 or or CC cord-006870-f5w6fw6q 1954 19 neurointervention neurointervention NN cord-006870-f5w6fw6q 1954 20 including include VBG cord-006870-f5w6fw6q 1954 21 angioplasty angioplasty NN cord-006870-f5w6fw6q 1954 22 and and CC cord-006870-f5w6fw6q 1954 23 extracranial extracranial JJ cord-006870-f5w6fw6q 1954 24 intracranial intracranial JJ cord-006870-f5w6fw6q 1954 25 arterial arterial JJ cord-006870-f5w6fw6q 1954 26 bypass bypass NN cord-006870-f5w6fw6q 1954 27 surgery surgery NN cord-006870-f5w6fw6q 1954 28 were be VBD cord-006870-f5w6fw6q 1954 29 performed perform VBN cord-006870-f5w6fw6q 1954 30 . . . cord-006870-f5w6fw6q 1955 1 52 52 CD cord-006870-f5w6fw6q 1955 2 patients patient NNS cord-006870-f5w6fw6q 1955 3 were be VBD cord-006870-f5w6fw6q 1955 4 analyzed analyze VBN cord-006870-f5w6fw6q 1955 5 . . . cord-006870-f5w6fw6q 1956 1 Territories territory NNS cord-006870-f5w6fw6q 1956 2 of of IN cord-006870-f5w6fw6q 1956 3 stroke stroke NN cord-006870-f5w6fw6q 1956 4 were be VBD cord-006870-f5w6fw6q 1956 5 31 31 CD cord-006870-f5w6fw6q 1956 6 of of IN cord-006870-f5w6fw6q 1956 7 anterior anterior JJ cord-006870-f5w6fw6q 1956 8 circulation circulation NN cord-006870-f5w6fw6q 1956 9 of of IN cord-006870-f5w6fw6q 1956 10 intracranial intracranial JJ cord-006870-f5w6fw6q 1956 11 vessels vessel NNS cord-006870-f5w6fw6q 1956 12 , , , cord-006870-f5w6fw6q 1956 13 11 11 CD cord-006870-f5w6fw6q 1956 14 of of IN cord-006870-f5w6fw6q 1956 15 posterior posterior JJ cord-006870-f5w6fw6q 1956 16 vessels vessel NNS cord-006870-f5w6fw6q 1956 17 , , , cord-006870-f5w6fw6q 1956 18 and and CC cord-006870-f5w6fw6q 1956 19 10 10 CD cord-006870-f5w6fw6q 1956 20 of of IN cord-006870-f5w6fw6q 1956 21 extracranial extracranial JJ cord-006870-f5w6fw6q 1956 22 vessels vessel NNS cord-006870-f5w6fw6q 1956 23 . . . cord-006870-f5w6fw6q 1957 1 Mean mean JJ cord-006870-f5w6fw6q 1957 2 duration duration NN cord-006870-f5w6fw6q 1957 3 of of IN cord-006870-f5w6fw6q 1957 4 IH IH NNP cord-006870-f5w6fw6q 1957 5 therapy therapy NN cord-006870-f5w6fw6q 1957 6 was be VBD cord-006870-f5w6fw6q 1957 7 4176.04 4176.04 CD cord-006870-f5w6fw6q 1957 8 minutes minute NNS cord-006870-f5w6fw6q 1957 9 . . . cord-006870-f5w6fw6q 1958 1 Pre pre JJ cord-006870-f5w6fw6q 1958 2 and and CC cord-006870-f5w6fw6q 1958 3 post post VB cord-006870-f5w6fw6q 1958 4 NIHSS NIHSS NNP cord-006870-f5w6fw6q 1958 5 score score NN cord-006870-f5w6fw6q 1958 6 of of IN cord-006870-f5w6fw6q 1958 7 IH IH NNP cord-006870-f5w6fw6q 1958 8 therapy therapy NN cord-006870-f5w6fw6q 1958 9 was be VBD cord-006870-f5w6fw6q 1958 10 8.19 8.19 CD cord-006870-f5w6fw6q 1958 11 and and CC cord-006870-f5w6fw6q 1958 12 7.35 7.35 CD cord-006870-f5w6fw6q 1958 13 , , , cord-006870-f5w6fw6q 1958 14 respectively respectively RB cord-006870-f5w6fw6q 1958 15 . . . cord-006870-f5w6fw6q 1959 1 30 30 CD cord-006870-f5w6fw6q 1959 2 patients patient NNS cord-006870-f5w6fw6q 1959 3 ( ( -LRB- cord-006870-f5w6fw6q 1959 4 57.7 57.7 CD cord-006870-f5w6fw6q 1959 5 % % NN cord-006870-f5w6fw6q 1959 6 ) ) -RRB- cord-006870-f5w6fw6q 1959 7 were be VBD cord-006870-f5w6fw6q 1959 8 showed show VBN cord-006870-f5w6fw6q 1959 9 improvement improvement NN cord-006870-f5w6fw6q 1959 10 and and CC cord-006870-f5w6fw6q 1959 11 13 13 CD cord-006870-f5w6fw6q 1959 12 patients patient NNS cord-006870-f5w6fw6q 1959 13 ( ( -LRB- cord-006870-f5w6fw6q 1959 14 25 25 CD cord-006870-f5w6fw6q 1959 15 % % NN cord-006870-f5w6fw6q 1959 16 ) ) -RRB- cord-006870-f5w6fw6q 1959 17 were be VBD cord-006870-f5w6fw6q 1959 18 stabilized stabilize VBN cord-006870-f5w6fw6q 1959 19 without without IN cord-006870-f5w6fw6q 1959 20 further further JJ cord-006870-f5w6fw6q 1959 21 aggravation aggravation NN cord-006870-f5w6fw6q 1959 22 . . . cord-006870-f5w6fw6q 1960 1 16 16 CD cord-006870-f5w6fw6q 1960 2 patients patient NNS cord-006870-f5w6fw6q 1960 3 revealed reveal VBD cord-006870-f5w6fw6q 1960 4 bradycardia bradycardia JJ cord-006870-f5w6fw6q 1960 5 . . . cord-006870-f5w6fw6q 1961 1 There there EX cord-006870-f5w6fw6q 1961 2 was be VBD cord-006870-f5w6fw6q 1961 3 no no DT cord-006870-f5w6fw6q 1961 4 fatal fatal JJ cord-006870-f5w6fw6q 1961 5 complication complication NN cord-006870-f5w6fw6q 1961 6 of of IN cord-006870-f5w6fw6q 1961 7 therapy therapy NN cord-006870-f5w6fw6q 1961 8 . . . cord-006870-f5w6fw6q 1962 1 15 15 CD cord-006870-f5w6fw6q 1962 2 patients patient NNS cord-006870-f5w6fw6q 1962 3 were be VBD cord-006870-f5w6fw6q 1962 4 performed perform VBN cord-006870-f5w6fw6q 1962 5 further further JJ cord-006870-f5w6fw6q 1962 6 treatment treatment NN cord-006870-f5w6fw6q 1962 7 include include VBP cord-006870-f5w6fw6q 1962 8 bypass bypass NN cord-006870-f5w6fw6q 1962 9 surgery surgery NN cord-006870-f5w6fw6q 1962 10 , , , cord-006870-f5w6fw6q 1962 11 angioplasty angioplasty NN cord-006870-f5w6fw6q 1962 12 , , , cord-006870-f5w6fw6q 1962 13 and and CC cord-006870-f5w6fw6q 1962 14 stenting stente VBG cord-006870-f5w6fw6q 1962 15 after after IN cord-006870-f5w6fw6q 1962 16 IH IH NNP cord-006870-f5w6fw6q 1962 17 therapy therapy NN cord-006870-f5w6fw6q 1962 18 . . . cord-006870-f5w6fw6q 1963 1 At at IN cord-006870-f5w6fw6q 1963 2 3 3 CD cord-006870-f5w6fw6q 1963 3 months month NNS cord-006870-f5w6fw6q 1963 4 follow follow VBP cord-006870-f5w6fw6q 1963 5 up up RB cord-006870-f5w6fw6q 1963 6 , , , cord-006870-f5w6fw6q 1963 7 34 34 CD cord-006870-f5w6fw6q 1963 8 patients patient NNS cord-006870-f5w6fw6q 1963 9 showed show VBD cord-006870-f5w6fw6q 1963 10 good good JJ cord-006870-f5w6fw6q 1963 11 outcomes outcome NNS cord-006870-f5w6fw6q 1963 12 ( ( -LRB- cord-006870-f5w6fw6q 1963 13 modified modify VBN cord-006870-f5w6fw6q 1963 14 Rankin Rankin NNP cord-006870-f5w6fw6q 1963 15 scale scale NN cord-006870-f5w6fw6q 1963 16 0 0 CD cord-006870-f5w6fw6q 1963 17 , , , cord-006870-f5w6fw6q 1963 18 1 1 CD cord-006870-f5w6fw6q 1963 19 , , , cord-006870-f5w6fw6q 1963 20 and and CC cord-006870-f5w6fw6q 1963 21 2 2 CD cord-006870-f5w6fw6q 1963 22 ) ) -RRB- cord-006870-f5w6fw6q 1963 23 . . . cord-006870-f5w6fw6q 1964 1 IHT IHT NNP cord-006870-f5w6fw6q 1964 2 may may MD cord-006870-f5w6fw6q 1964 3 be be VB cord-006870-f5w6fw6q 1964 4 safe safe JJ cord-006870-f5w6fw6q 1964 5 and and CC cord-006870-f5w6fw6q 1964 6 effective effective JJ cord-006870-f5w6fw6q 1964 7 for for IN cord-006870-f5w6fw6q 1964 8 the the DT cord-006870-f5w6fw6q 1964 9 neurologic neurologic JJ cord-006870-f5w6fw6q 1964 10 deterioration deterioration NN cord-006870-f5w6fw6q 1964 11 or or CC cord-006870-f5w6fw6q 1964 12 progression progression NN cord-006870-f5w6fw6q 1964 13 of of IN cord-006870-f5w6fw6q 1964 14 acute acute JJ cord-006870-f5w6fw6q 1964 15 ischemic ischemic JJ cord-006870-f5w6fw6q 1964 16 stroke stroke NN cord-006870-f5w6fw6q 1964 17 with with IN cord-006870-f5w6fw6q 1964 18 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 1964 19 instability instability NN cord-006870-f5w6fw6q 1964 20 due due IN cord-006870-f5w6fw6q 1964 21 to to IN cord-006870-f5w6fw6q 1964 22 severe severe JJ cord-006870-f5w6fw6q 1964 23 steno steno NN cord-006870-f5w6fw6q 1964 24 - - HYPH cord-006870-f5w6fw6q 1964 25 occlusive occlusive JJ cord-006870-f5w6fw6q 1964 26 disease disease NN cord-006870-f5w6fw6q 1964 27 of of IN cord-006870-f5w6fw6q 1964 28 major major JJ cord-006870-f5w6fw6q 1964 29 cerebral cerebral JJ cord-006870-f5w6fw6q 1964 30 artery artery NN cord-006870-f5w6fw6q 1964 31 . . . cord-006870-f5w6fw6q 1965 1 Large large JJ cord-006870-f5w6fw6q 1965 2 randomized randomized JJ cord-006870-f5w6fw6q 1965 3 trials trial NNS cord-006870-f5w6fw6q 1965 4 are be VBP cord-006870-f5w6fw6q 1965 5 needed need VBN cord-006870-f5w6fw6q 1965 6 to to TO cord-006870-f5w6fw6q 1965 7 confirm confirm VB cord-006870-f5w6fw6q 1965 8 this this DT cord-006870-f5w6fw6q 1965 9 result result NN cord-006870-f5w6fw6q 1965 10 . . . cord-006870-f5w6fw6q 1966 1 Most Most JJS cord-006870-f5w6fw6q 1966 2 patients patient NNS cord-006870-f5w6fw6q 1966 3 with with IN cord-006870-f5w6fw6q 1966 4 progressive progressive JJ cord-006870-f5w6fw6q 1966 5 stroke stroke NN cord-006870-f5w6fw6q 1966 6 have have VB cord-006870-f5w6fw6q 1966 7 a a DT cord-006870-f5w6fw6q 1966 8 poor poor JJ cord-006870-f5w6fw6q 1966 9 prognosis prognosis NN cord-006870-f5w6fw6q 1966 10 . . . cord-006870-f5w6fw6q 1967 1 The the DT cord-006870-f5w6fw6q 1967 2 aim aim NN cord-006870-f5w6fw6q 1967 3 of of IN cord-006870-f5w6fw6q 1967 4 our -PRON- PRP$ cord-006870-f5w6fw6q 1967 5 study study NN cord-006870-f5w6fw6q 1967 6 was be VBD cord-006870-f5w6fw6q 1967 7 investigate investigate VB cord-006870-f5w6fw6q 1967 8 the the DT cord-006870-f5w6fw6q 1967 9 factors factor NNS cord-006870-f5w6fw6q 1967 10 related relate VBN cord-006870-f5w6fw6q 1967 11 with with IN cord-006870-f5w6fw6q 1967 12 progressive progressive JJ cord-006870-f5w6fw6q 1967 13 neurologic neurologic JJ cord-006870-f5w6fw6q 1967 14 deficit deficit NN cord-006870-f5w6fw6q 1967 15 ( ( -LRB- cord-006870-f5w6fw6q 1967 16 PND PND NNP cord-006870-f5w6fw6q 1967 17 ) ) -RRB- cord-006870-f5w6fw6q 1967 18 in in IN cord-006870-f5w6fw6q 1967 19 the the DT cord-006870-f5w6fw6q 1967 20 patients patient NNS cord-006870-f5w6fw6q 1967 21 receiving receive VBG cord-006870-f5w6fw6q 1967 22 recanalization recanalization NN cord-006870-f5w6fw6q 1967 23 therapy therapy NN cord-006870-f5w6fw6q 1967 24 for for IN cord-006870-f5w6fw6q 1967 25 acute acute JJ cord-006870-f5w6fw6q 1967 26 ischemic ischemic JJ cord-006870-f5w6fw6q 1967 27 stroke stroke NN cord-006870-f5w6fw6q 1967 28 . . . cord-006870-f5w6fw6q 1968 1 -month -month JJ cord-006870-f5w6fw6q 1968 2 period period NN cord-006870-f5w6fw6q 1968 3 , , , cord-006870-f5w6fw6q 1968 4 were be VBD cord-006870-f5w6fw6q 1968 5 enrolled enrol VBN cord-006870-f5w6fw6q 1968 6 . . . cord-006870-f5w6fw6q 1969 1 Blood blood NN cord-006870-f5w6fw6q 1969 2 pressures pressure NNS cord-006870-f5w6fw6q 1969 3 ( ( -LRB- cord-006870-f5w6fw6q 1969 4 BPs bp NNS cord-006870-f5w6fw6q 1969 5 ) ) -RRB- cord-006870-f5w6fw6q 1969 6 at at IN cord-006870-f5w6fw6q 1969 7 0 0 CD cord-006870-f5w6fw6q 1969 8 , , , cord-006870-f5w6fw6q 1969 9 12 12 CD cord-006870-f5w6fw6q 1969 10 , , , cord-006870-f5w6fw6q 1969 11 and and CC cord-006870-f5w6fw6q 1969 12 24 24 CD cord-006870-f5w6fw6q 1969 13 hours hour NNS cord-006870-f5w6fw6q 1969 14 after after IN cord-006870-f5w6fw6q 1969 15 admission admission NN cord-006870-f5w6fw6q 1969 16 and and CC cord-006870-f5w6fw6q 1969 17 BP BP NNP cord-006870-f5w6fw6q 1969 18 variation variation NN cord-006870-f5w6fw6q 1969 19 ( ( -LRB- cord-006870-f5w6fw6q 1969 20 BPV BPV NNP cord-006870-f5w6fw6q 1969 21 ) ) -RRB- cord-006870-f5w6fw6q 1969 22 for for IN cord-006870-f5w6fw6q 1969 23 the the DT cord-006870-f5w6fw6q 1969 24 first first JJ cord-006870-f5w6fw6q 1969 25 24 24 CD cord-006870-f5w6fw6q 1969 26 hours hour NNS cord-006870-f5w6fw6q 1969 27 were be VBD cord-006870-f5w6fw6q 1969 28 collected collect VBN cord-006870-f5w6fw6q 1969 29 . . . cord-006870-f5w6fw6q 1970 1 Variables variable NNS cord-006870-f5w6fw6q 1970 2 associated associate VBN cord-006870-f5w6fw6q 1970 3 with with IN cord-006870-f5w6fw6q 1970 4 PND PND NNP cord-006870-f5w6fw6q 1970 5 were be VBD cord-006870-f5w6fw6q 1970 6 analyzed analyze VBN cord-006870-f5w6fw6q 1970 7 . . . cord-006870-f5w6fw6q 1971 1 Among among IN cord-006870-f5w6fw6q 1971 2 216 216 CD cord-006870-f5w6fw6q 1971 3 enrolled enrol VBN cord-006870-f5w6fw6q 1971 4 patients patient NNS cord-006870-f5w6fw6q 1971 5 , , , cord-006870-f5w6fw6q 1971 6 68 68 CD cord-006870-f5w6fw6q 1971 7 patients patient NNS cord-006870-f5w6fw6q 1971 8 showed show VBD cord-006870-f5w6fw6q 1971 9 PND PND NNP cord-006870-f5w6fw6q 1971 10 . . . cord-006870-f5w6fw6q 1972 1 The the DT cord-006870-f5w6fw6q 1972 2 patients patient NNS cord-006870-f5w6fw6q 1972 3 with with IN cord-006870-f5w6fw6q 1972 4 PND PND NNP cord-006870-f5w6fw6q 1972 5 had have VBD cord-006870-f5w6fw6q 1972 6 higher high JJR cord-006870-f5w6fw6q 1972 7 systolic systolic JJ cord-006870-f5w6fw6q 1972 8 BPs bp NNS cord-006870-f5w6fw6q 1972 9 at at IN cord-006870-f5w6fw6q 1972 10 0 0 CD cord-006870-f5w6fw6q 1972 11 , , , cord-006870-f5w6fw6q 1972 12 12 12 CD cord-006870-f5w6fw6q 1972 13 , , , cord-006870-f5w6fw6q 1972 14 and and CC cord-006870-f5w6fw6q 1972 15 24 24 CD cord-006870-f5w6fw6q 1972 16 hours hour NNS cord-006870-f5w6fw6q 1972 17 after after IN cord-006870-f5w6fw6q 1972 18 admission admission NN cord-006870-f5w6fw6q 1972 19 and and CC cord-006870-f5w6fw6q 1972 20 higher high JJR cord-006870-f5w6fw6q 1972 21 BPV BPV NNP cord-006870-f5w6fw6q 1972 22 than than IN cord-006870-f5w6fw6q 1972 23 the the DT cord-006870-f5w6fw6q 1972 24 others other NNS cord-006870-f5w6fw6q 1972 25 ( ( -LRB- cord-006870-f5w6fw6q 1972 26 p p NN cord-006870-f5w6fw6q 1972 27 < < XX cord-006870-f5w6fw6q 1972 28 0.05 0.05 CD cord-006870-f5w6fw6q 1972 29 ) ) -RRB- cord-006870-f5w6fw6q 1972 30 . . . cord-006870-f5w6fw6q 1973 1 Posterior posterior JJ cord-006870-f5w6fw6q 1973 2 circulation circulation NN cord-006870-f5w6fw6q 1973 3 stroke stroke NN cord-006870-f5w6fw6q 1973 4 was be VBD cord-006870-f5w6fw6q 1973 5 more more RBR cord-006870-f5w6fw6q 1973 6 prevalent prevalent JJ cord-006870-f5w6fw6q 1973 7 in in IN cord-006870-f5w6fw6q 1973 8 the the DT cord-006870-f5w6fw6q 1973 9 patients patient NNS cord-006870-f5w6fw6q 1973 10 with with IN cord-006870-f5w6fw6q 1973 11 PND PND NNP cord-006870-f5w6fw6q 1973 12 ( ( -LRB- cord-006870-f5w6fw6q 1973 13 p p NN cord-006870-f5w6fw6q 1973 14 < < XX cord-006870-f5w6fw6q 1973 15 0.01 0.01 CD cord-006870-f5w6fw6q 1973 16 ) ) -RRB- cord-006870-f5w6fw6q 1973 17 . . . cord-006870-f5w6fw6q 1974 1 In in IN cord-006870-f5w6fw6q 1974 2 logistic logistic JJ cord-006870-f5w6fw6q 1974 3 regression regression NN cord-006870-f5w6fw6q 1974 4 analysis analysis NN cord-006870-f5w6fw6q 1974 5 , , , cord-006870-f5w6fw6q 1974 6 PND PND NNP cord-006870-f5w6fw6q 1974 7 was be VBD cord-006870-f5w6fw6q 1974 8 independently independently RB cord-006870-f5w6fw6q 1974 9 associated associate VBN cord-006870-f5w6fw6q 1974 10 with with IN cord-006870-f5w6fw6q 1974 11 posterior posterior JJ cord-006870-f5w6fw6q 1974 12 circulation circulation NN cord-006870-f5w6fw6q 1974 13 stroke stroke NN cord-006870-f5w6fw6q 1974 14 [ [ -LRB- cord-006870-f5w6fw6q 1974 15 odds odd NNS cord-006870-f5w6fw6q 1974 16 ratio ratio NN cord-006870-f5w6fw6q 1974 17 ( ( -LRB- cord-006870-f5w6fw6q 1974 18 OR or NN cord-006870-f5w6fw6q 1974 19 ) ) -RRB- cord-006870-f5w6fw6q 1974 20 = = NFP cord-006870-f5w6fw6q 1975 1 3.35 3.35 CD cord-006870-f5w6fw6q 1975 2 , , , cord-006870-f5w6fw6q 1975 3 p p NN cord-006870-f5w6fw6q 1975 4 < < XX cord-006870-f5w6fw6q 1975 5 0.001 0.001 CD cord-006870-f5w6fw6q 1975 6 ] ] -RRB- cord-006870-f5w6fw6q 1975 7 and and CC cord-006870-f5w6fw6q 1975 8 systolic systolic JJ cord-006870-f5w6fw6q 1975 9 BP BP NNP cord-006870-f5w6fw6q 1975 10 at at IN cord-006870-f5w6fw6q 1975 11 24 24 CD cord-006870-f5w6fw6q 1975 12 hours hour NNS cord-006870-f5w6fw6q 1975 13 after after IN cord-006870-f5w6fw6q 1975 14 admission admission NN cord-006870-f5w6fw6q 1975 15 ( ( -LRB- cord-006870-f5w6fw6q 1975 16 OR or RB cord-006870-f5w6fw6q 1976 1 = = SYM cord-006870-f5w6fw6q 1976 2 1.02 1.02 CD cord-006870-f5w6fw6q 1976 3 , , , cord-006870-f5w6fw6q 1976 4 p p NN cord-006870-f5w6fw6q 1976 5 = = SYM cord-006870-f5w6fw6q 1976 6 0.03 0.03 CD cord-006870-f5w6fw6q 1976 7 ) ) -RRB- cord-006870-f5w6fw6q 1976 8 . . . cord-006870-f5w6fw6q 1977 1 PND PND NNP cord-006870-f5w6fw6q 1977 2 may may MD cord-006870-f5w6fw6q 1977 3 be be VB cord-006870-f5w6fw6q 1977 4 associated associate VBN cord-006870-f5w6fw6q 1977 5 with with IN cord-006870-f5w6fw6q 1977 6 elevated elevated JJ cord-006870-f5w6fw6q 1977 7 systolic systolic JJ cord-006870-f5w6fw6q 1977 8 BP BP NNP cord-006870-f5w6fw6q 1977 9 for for IN cord-006870-f5w6fw6q 1977 10 the the DT cord-006870-f5w6fw6q 1977 11 first first JJ cord-006870-f5w6fw6q 1977 12 24 24 CD cord-006870-f5w6fw6q 1977 13 hours hour NNS cord-006870-f5w6fw6q 1977 14 after after IN cord-006870-f5w6fw6q 1977 15 admission admission NN cord-006870-f5w6fw6q 1977 16 in in IN cord-006870-f5w6fw6q 1977 17 the the DT cord-006870-f5w6fw6q 1977 18 patients patient NNS cord-006870-f5w6fw6q 1977 19 receiving receive VBG cord-006870-f5w6fw6q 1977 20 recanalization recanalization NN cord-006870-f5w6fw6q 1977 21 therapy therapy NN cord-006870-f5w6fw6q 1977 22 for for IN cord-006870-f5w6fw6q 1977 23 acute acute JJ cord-006870-f5w6fw6q 1977 24 ischemic ischemic JJ cord-006870-f5w6fw6q 1977 25 stroke stroke NN cord-006870-f5w6fw6q 1977 26 . . . cord-006870-f5w6fw6q 1978 1 Telestroke Telestroke NNP cord-006870-f5w6fw6q 1978 2 has have VBZ cord-006870-f5w6fw6q 1978 3 revolutionized revolutionize VBN cord-006870-f5w6fw6q 1978 4 stroke stroke NN cord-006870-f5w6fw6q 1978 5 care care NN cord-006870-f5w6fw6q 1978 6 delivery delivery NN cord-006870-f5w6fw6q 1978 7 in in IN cord-006870-f5w6fw6q 1978 8 the the DT cord-006870-f5w6fw6q 1978 9 modern modern JJ cord-006870-f5w6fw6q 1978 10 era era NN cord-006870-f5w6fw6q 1978 11 . . . cord-006870-f5w6fw6q 1979 1 Massachusetts Massachusetts NNP cord-006870-f5w6fw6q 1979 2 General General NNP cord-006870-f5w6fw6q 1979 3 Hospital Hospital NNP cord-006870-f5w6fw6q 1979 4 ( ( -LRB- cord-006870-f5w6fw6q 1979 5 MGH MGH NNP cord-006870-f5w6fw6q 1979 6 ) ) -RRB- cord-006870-f5w6fw6q 1979 7 uses use VBZ cord-006870-f5w6fw6q 1979 8 the the DT cord-006870-f5w6fw6q 1979 9 most most RBS cord-006870-f5w6fw6q 1979 10 common common JJ cord-006870-f5w6fw6q 1979 11 model model NN cord-006870-f5w6fw6q 1979 12 , , , cord-006870-f5w6fw6q 1979 13 the the DT cord-006870-f5w6fw6q 1979 14 hub hub NN cord-006870-f5w6fw6q 1979 15 and and CC cord-006870-f5w6fw6q 1979 16 spoke speak VBD cord-006870-f5w6fw6q 1979 17 . . . cord-006870-f5w6fw6q 1980 1 The the DT cord-006870-f5w6fw6q 1980 2 demonstration demonstration NN cord-006870-f5w6fw6q 1980 3 of of IN cord-006870-f5w6fw6q 1980 4 superiority superiority NN cord-006870-f5w6fw6q 1980 5 of of IN cord-006870-f5w6fw6q 1980 6 endovascular endovascular JJ cord-006870-f5w6fw6q 1980 7 therapy therapy NN cord-006870-f5w6fw6q 1980 8 ( ( -LRB- cord-006870-f5w6fw6q 1980 9 ET ET NNP cord-006870-f5w6fw6q 1980 10 ) ) -RRB- cord-006870-f5w6fw6q 1980 11 with with IN cord-006870-f5w6fw6q 1980 12 intravenous intravenous JJ cord-006870-f5w6fw6q 1980 13 tPA tPA NNP cord-006870-f5w6fw6q 1980 14 over over IN cord-006870-f5w6fw6q 1980 15 tPA tPA NNP cord-006870-f5w6fw6q 1980 16 alone alone JJ cord-006870-f5w6fw6q 1980 17 for for IN cord-006870-f5w6fw6q 1980 18 acute acute JJ cord-006870-f5w6fw6q 1980 19 stroke stroke NN cord-006870-f5w6fw6q 1980 20 patients patient NNS cord-006870-f5w6fw6q 1980 21 with with IN cord-006870-f5w6fw6q 1980 22 large large JJ cord-006870-f5w6fw6q 1980 23 vessel vessel NN cord-006870-f5w6fw6q 1980 24 occlusions occlusion NNS cord-006870-f5w6fw6q 1980 25 prompts prompt VBZ cord-006870-f5w6fw6q 1980 26 a a DT cord-006870-f5w6fw6q 1980 27 thorough thorough JJ cord-006870-f5w6fw6q 1980 28 assessment assessment NN cord-006870-f5w6fw6q 1980 29 of of IN cord-006870-f5w6fw6q 1980 30 Telestroke Telestroke NNP cord-006870-f5w6fw6q 1980 31 's 's POS cord-006870-f5w6fw6q 1980 32 role role NN cord-006870-f5w6fw6q 1980 33 in in IN cord-006870-f5w6fw6q 1980 34 the the DT cord-006870-f5w6fw6q 1980 35 delivery delivery NN cord-006870-f5w6fw6q 1980 36 of of IN cord-006870-f5w6fw6q 1980 37 ET ET NNP cord-006870-f5w6fw6q 1980 38 , , , cord-006870-f5w6fw6q 1980 39 particularly particularly RB cord-006870-f5w6fw6q 1980 40 in in IN cord-006870-f5w6fw6q 1980 41 terms term NNS cord-006870-f5w6fw6q 1980 42 of of IN cord-006870-f5w6fw6q 1980 43 transferring transfer VBG cord-006870-f5w6fw6q 1980 44 patients patient NNS cord-006870-f5w6fw6q 1980 45 to to TO cord-006870-f5w6fw6q 1980 46 hubs hub NNS cord-006870-f5w6fw6q 1980 47 capable capable JJ cord-006870-f5w6fw6q 1980 48 of of IN cord-006870-f5w6fw6q 1980 49 ET ET NNP cord-006870-f5w6fw6q 1980 50 . . . cord-006870-f5w6fw6q 1981 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 1981 2 primary primary JJ cord-006870-f5w6fw6q 1981 3 objective objective NN cord-006870-f5w6fw6q 1981 4 was be VBD cord-006870-f5w6fw6q 1981 5 to to TO cord-006870-f5w6fw6q 1981 6 examine examine VB cord-006870-f5w6fw6q 1981 7 associations association NNS cord-006870-f5w6fw6q 1981 8 between between IN cord-006870-f5w6fw6q 1981 9 transfer transfer NN cord-006870-f5w6fw6q 1981 10 time time NN cord-006870-f5w6fw6q 1981 11 and and CC cord-006870-f5w6fw6q 1981 12 clinical clinical JJ cord-006870-f5w6fw6q 1981 13 outcomes outcome NNS cord-006870-f5w6fw6q 1981 14 . . . cord-006870-f5w6fw6q 1982 1 Patients patient NNS cord-006870-f5w6fw6q 1982 2 were be VBD cord-006870-f5w6fw6q 1982 3 selected select VBN cord-006870-f5w6fw6q 1982 4 from from IN cord-006870-f5w6fw6q 1982 5 the the DT cord-006870-f5w6fw6q 1982 6 Get get NN cord-006870-f5w6fw6q 1982 7 with with IN cord-006870-f5w6fw6q 1982 8 the the DT cord-006870-f5w6fw6q 1982 9 Guidelines Guidelines NNPS cord-006870-f5w6fw6q 1982 10 - - HYPH cord-006870-f5w6fw6q 1982 11 Stroke stroke NN cord-006870-f5w6fw6q 1982 12 registry registry NN cord-006870-f5w6fw6q 1982 13 who who WP cord-006870-f5w6fw6q 1982 14 were be VBD cord-006870-f5w6fw6q 1982 15 transferred transfer VBN cord-006870-f5w6fw6q 1982 16 to to IN cord-006870-f5w6fw6q 1982 17 MGH MGH NNP cord-006870-f5w6fw6q 1982 18 from from IN cord-006870-f5w6fw6q 1982 19 Jan Jan NNP cord-006870-f5w6fw6q 1982 20 2011 2011 CD cord-006870-f5w6fw6q 1982 21 to to IN cord-006870-f5w6fw6q 1982 22 Oct Oct NNP cord-006870-f5w6fw6q 1982 23 2015 2015 CD cord-006870-f5w6fw6q 1982 24 who who WP cord-006870-f5w6fw6q 1982 25 had have VBD cord-006870-f5w6fw6q 1982 26 NIHSS>6 nihss>6 NN cord-006870-f5w6fw6q 1982 27 and and CC cord-006870-f5w6fw6q 1982 28 last last JJ cord-006870-f5w6fw6q 1982 29 known know VBN cord-006870-f5w6fw6q 1982 30 well<12h well<12h NNS cord-006870-f5w6fw6q 1982 31 on on IN cord-006870-f5w6fw6q 1982 32 MGH MGH NNP cord-006870-f5w6fw6q 1982 33 arrival arrival NN cord-006870-f5w6fw6q 1982 34 ( ( -LRB- cord-006870-f5w6fw6q 1982 35 n=618 n=618 NFP cord-006870-f5w6fw6q 1982 36 ) ) -RRB- cord-006870-f5w6fw6q 1982 37 . . . cord-006870-f5w6fw6q 1983 1 We -PRON- PRP cord-006870-f5w6fw6q 1983 2 excluded exclude VBD cord-006870-f5w6fw6q 1983 3 patients patient NNS cord-006870-f5w6fw6q 1983 4 for for IN cord-006870-f5w6fw6q 1983 5 whom whom WP cord-006870-f5w6fw6q 1983 6 we -PRON- PRP cord-006870-f5w6fw6q 1983 7 could could MD cord-006870-f5w6fw6q 1983 8 not not RB cord-006870-f5w6fw6q 1983 9 calculate calculate VB cord-006870-f5w6fw6q 1983 10 the the DT cord-006870-f5w6fw6q 1983 11 primary primary JJ cord-006870-f5w6fw6q 1983 12 predictor predictor NN cord-006870-f5w6fw6q 1983 13 , , , cord-006870-f5w6fw6q 1983 14 transfer transfer NN cord-006870-f5w6fw6q 1983 15 time time NN cord-006870-f5w6fw6q 1983 16 ( ( -LRB- cord-006870-f5w6fw6q 1983 17 defined define VBN cord-006870-f5w6fw6q 1983 18 as as IN cord-006870-f5w6fw6q 1983 19 the the DT cord-006870-f5w6fw6q 1983 20 MGH MGH NNP cord-006870-f5w6fw6q 1983 21 arrival arrival NN cord-006870-f5w6fw6q 1983 22 time time NN cord-006870-f5w6fw6q 1984 1 minus minus CC cord-006870-f5w6fw6q 1985 1 the the DT cord-006870-f5w6fw6q 1985 2 telestroke telestroke NNP cord-006870-f5w6fw6q 1985 3 consult consult VBP cord-006870-f5w6fw6q 1985 4 answered answer VBN cord-006870-f5w6fw6q 1985 5 time time NN cord-006870-f5w6fw6q 1985 6 , , , cord-006870-f5w6fw6q 1985 7 n=384 n=384 NNP cord-006870-f5w6fw6q 1985 8 ) ) -RRB- cord-006870-f5w6fw6q 1985 9 . . . cord-006870-f5w6fw6q 1986 1 Several several JJ cord-006870-f5w6fw6q 1986 2 clinical clinical JJ cord-006870-f5w6fw6q 1986 3 outcomes outcome NNS cord-006870-f5w6fw6q 1986 4 were be VBD cord-006870-f5w6fw6q 1986 5 explored explore VBN cord-006870-f5w6fw6q 1986 6 by by IN cord-006870-f5w6fw6q 1986 7 linear linear JJ cord-006870-f5w6fw6q 1986 8 and and CC cord-006870-f5w6fw6q 1986 9 logistic logistic JJ cord-006870-f5w6fw6q 1986 10 regression regression NN cord-006870-f5w6fw6q 1986 11 to to TO cord-006870-f5w6fw6q 1986 12 determine determine VB cord-006870-f5w6fw6q 1986 13 association association NN cord-006870-f5w6fw6q 1986 14 with with IN cord-006870-f5w6fw6q 1986 15 transfer transfer NN cord-006870-f5w6fw6q 1986 16 time time NN cord-006870-f5w6fw6q 1986 17 . . . cord-006870-f5w6fw6q 1987 1 Of of IN cord-006870-f5w6fw6q 1987 2 the the DT cord-006870-f5w6fw6q 1987 3 234 234 CD cord-006870-f5w6fw6q 1987 4 patients patient NNS cord-006870-f5w6fw6q 1987 5 in in IN cord-006870-f5w6fw6q 1987 6 the the DT cord-006870-f5w6fw6q 1987 7 study study NN cord-006870-f5w6fw6q 1987 8 , , , cord-006870-f5w6fw6q 1987 9 120 120 CD cord-006870-f5w6fw6q 1987 10 ( ( -LRB- cord-006870-f5w6fw6q 1987 11 51 51 CD cord-006870-f5w6fw6q 1987 12 % % NN cord-006870-f5w6fw6q 1987 13 ) ) -RRB- cord-006870-f5w6fw6q 1987 14 were be VBD cord-006870-f5w6fw6q 1987 15 transferred transfer VBN cord-006870-f5w6fw6q 1987 16 by by IN cord-006870-f5w6fw6q 1987 17 ambulance ambulance NN cord-006870-f5w6fw6q 1987 18 , , , cord-006870-f5w6fw6q 1987 19 114 114 CD cord-006870-f5w6fw6q 1987 20 ( ( -LRB- cord-006870-f5w6fw6q 1987 21 49 49 CD cord-006870-f5w6fw6q 1987 22 % % NN cord-006870-f5w6fw6q 1987 23 ) ) -RRB- cord-006870-f5w6fw6q 1987 24 by by IN cord-006870-f5w6fw6q 1987 25 helicopter helicopter NN cord-006870-f5w6fw6q 1987 26 , , , cord-006870-f5w6fw6q 1987 27 and and CC cord-006870-f5w6fw6q 1987 28 63 63 CD cord-006870-f5w6fw6q 1987 29 ( ( -LRB- cord-006870-f5w6fw6q 1987 30 27 27 CD cord-006870-f5w6fw6q 1987 31 % % NN cord-006870-f5w6fw6q 1987 32 ) ) -RRB- cord-006870-f5w6fw6q 1988 1 underwent undergo VBD cord-006870-f5w6fw6q 1988 2 ET ET NNP cord-006870-f5w6fw6q 1988 3 at at IN cord-006870-f5w6fw6q 1988 4 MGH MGH NNP cord-006870-f5w6fw6q 1988 5 . . . cord-006870-f5w6fw6q 1989 1 Median median JJ cord-006870-f5w6fw6q 1989 2 transfer transfer NN cord-006870-f5w6fw6q 1989 3 time time NN cord-006870-f5w6fw6q 1989 4 was be VBD cord-006870-f5w6fw6q 1989 5 132 132 CD cord-006870-f5w6fw6q 1989 6 min min NN cord-006870-f5w6fw6q 1989 7 , , , cord-006870-f5w6fw6q 1989 8 and and CC cord-006870-f5w6fw6q 1989 9 median median JJ cord-006870-f5w6fw6q 1989 10 ASPECTS aspects JJ cord-006870-f5w6fw6q 1989 11 decrease decrease NN cord-006870-f5w6fw6q 1989 12 was be VBD cord-006870-f5w6fw6q 1989 13 2 2 CD cord-006870-f5w6fw6q 1989 14 during during IN cord-006870-f5w6fw6q 1989 15 transfer transfer NN cord-006870-f5w6fw6q 1989 16 . . . cord-006870-f5w6fw6q 1990 1 Longer long JJR cord-006870-f5w6fw6q 1990 2 transfer transfer VB cord-006870-f5w6fw6q 1990 3 time time NN cord-006870-f5w6fw6q 1990 4 was be VBD cord-006870-f5w6fw6q 1990 5 associated associate VBN cord-006870-f5w6fw6q 1990 6 with with IN cord-006870-f5w6fw6q 1990 7 decreased decrease VBN cord-006870-f5w6fw6q 1990 8 likelihood likelihood NN cord-006870-f5w6fw6q 1990 9 of of IN cord-006870-f5w6fw6q 1990 10 undergoing undergo VBG cord-006870-f5w6fw6q 1990 11 ET ET NNP cord-006870-f5w6fw6q 1990 12 ( ( -LRB- cord-006870-f5w6fw6q 1990 13 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 1990 14 ) ) -RRB- cord-006870-f5w6fw6q 1990 15 . . . cord-006870-f5w6fw6q 1991 1 However however RB cord-006870-f5w6fw6q 1991 2 , , , cord-006870-f5w6fw6q 1991 3 transfer transfer NN cord-006870-f5w6fw6q 1991 4 time time NN cord-006870-f5w6fw6q 1991 5 was be VBD cord-006870-f5w6fw6q 1991 6 not not RB cord-006870-f5w6fw6q 1991 7 significantly significantly RB cord-006870-f5w6fw6q 1991 8 associated associate VBN cord-006870-f5w6fw6q 1991 9 with with IN cord-006870-f5w6fw6q 1991 10 ASPECTS aspects JJ cord-006870-f5w6fw6q 1991 11 decrease decrease NN cord-006870-f5w6fw6q 1991 12 during during IN cord-006870-f5w6fw6q 1991 13 transfer transfer NN cord-006870-f5w6fw6q 1991 14 . . . cord-006870-f5w6fw6q 1992 1 For for IN cord-006870-f5w6fw6q 1992 2 those those DT cord-006870-f5w6fw6q 1992 3 patients patient NNS cord-006870-f5w6fw6q 1992 4 undergoing undergo VBG cord-006870-f5w6fw6q 1992 5 ET ET NNP cord-006870-f5w6fw6q 1992 6 , , , cord-006870-f5w6fw6q 1992 7 transfer transfer NN cord-006870-f5w6fw6q 1992 8 times time NNS cord-006870-f5w6fw6q 1992 9 bore bear VBD cord-006870-f5w6fw6q 1992 10 no no DT cord-006870-f5w6fw6q 1992 11 association association NN cord-006870-f5w6fw6q 1992 12 to to IN cord-006870-f5w6fw6q 1992 13 90 90 CD cord-006870-f5w6fw6q 1992 14 day day NN cord-006870-f5w6fw6q 1992 15 mRS mrs NN cord-006870-f5w6fw6q 1992 16 . . . cord-006870-f5w6fw6q 1993 1 This this DT cord-006870-f5w6fw6q 1993 2 study study NN cord-006870-f5w6fw6q 1993 3 identifies identify VBZ cord-006870-f5w6fw6q 1993 4 an an DT cord-006870-f5w6fw6q 1993 5 association association NN cord-006870-f5w6fw6q 1993 6 between between IN cord-006870-f5w6fw6q 1993 7 longer long JJR cord-006870-f5w6fw6q 1993 8 transfer transfer NN cord-006870-f5w6fw6q 1993 9 time time NN cord-006870-f5w6fw6q 1993 10 and and CC cord-006870-f5w6fw6q 1993 11 decreased decrease VBD cord-006870-f5w6fw6q 1993 12 likelihood likelihood NN cord-006870-f5w6fw6q 1993 13 of of IN cord-006870-f5w6fw6q 1993 14 undergoing undergo VBG cord-006870-f5w6fw6q 1993 15 ET ET NNP cord-006870-f5w6fw6q 1993 16 . . . cord-006870-f5w6fw6q 1994 1 Reasons reason NNS cord-006870-f5w6fw6q 1994 2 are be VBP cord-006870-f5w6fw6q 1994 3 varied varied JJ cord-006870-f5w6fw6q 1994 4 , , , cord-006870-f5w6fw6q 1994 5 and and CC cord-006870-f5w6fw6q 1994 6 are be VBP cord-006870-f5w6fw6q 1994 7 not not RB cord-006870-f5w6fw6q 1994 8 clearly clearly RB cord-006870-f5w6fw6q 1994 9 related relate VBN cord-006870-f5w6fw6q 1994 10 to to IN cord-006870-f5w6fw6q 1994 11 imaging imaging NN cord-006870-f5w6fw6q 1994 12 progression progression NN cord-006870-f5w6fw6q 1994 13 alone alone RB cord-006870-f5w6fw6q 1994 14 . . . cord-006870-f5w6fw6q 1995 1 Only only RB cord-006870-f5w6fw6q 1995 2 27 27 CD cord-006870-f5w6fw6q 1995 3 % % NN cord-006870-f5w6fw6q 1995 4 of of IN cord-006870-f5w6fw6q 1995 5 transferred transfer VBN cord-006870-f5w6fw6q 1995 6 patients patient NNS cord-006870-f5w6fw6q 1995 7 underwent undergo VBD cord-006870-f5w6fw6q 1995 8 ET ET NNP cord-006870-f5w6fw6q 1995 9 . . . cord-006870-f5w6fw6q 1996 1 More more RBR cord-006870-f5w6fw6q 1996 2 efficient efficient JJ cord-006870-f5w6fw6q 1996 3 spoke speak VBD cord-006870-f5w6fw6q 1996 4 triage triage NN cord-006870-f5w6fw6q 1996 5 and and CC cord-006870-f5w6fw6q 1996 6 transfer transfer NN cord-006870-f5w6fw6q 1996 7 may may MD cord-006870-f5w6fw6q 1996 8 improve improve VB cord-006870-f5w6fw6q 1996 9 the the DT cord-006870-f5w6fw6q 1996 10 ratio ratio NN cord-006870-f5w6fw6q 1996 11 of of IN cord-006870-f5w6fw6q 1996 12 patients patient NNS cord-006870-f5w6fw6q 1996 13 treated treat VBN cord-006870-f5w6fw6q 1996 14 with with IN cord-006870-f5w6fw6q 1996 15 ET ET NNP cord-006870-f5w6fw6q 1996 16 . . . cord-006870-f5w6fw6q 1997 1 These these DT cord-006870-f5w6fw6q 1997 2 data datum NNS cord-006870-f5w6fw6q 1997 3 provide provide VBP cord-006870-f5w6fw6q 1997 4 an an DT cord-006870-f5w6fw6q 1997 5 important important JJ cord-006870-f5w6fw6q 1997 6 perspective perspective NN cord-006870-f5w6fw6q 1997 7 during during IN cord-006870-f5w6fw6q 1997 8 this this DT cord-006870-f5w6fw6q 1997 9 period period NN cord-006870-f5w6fw6q 1997 10 of of IN cord-006870-f5w6fw6q 1997 11 stroke stroke NN cord-006870-f5w6fw6q 1997 12 triage triage NN cord-006870-f5w6fw6q 1997 13 evolution evolution NN cord-006870-f5w6fw6q 1997 14 . . . cord-006870-f5w6fw6q 1998 1 Intra intra JJ cord-006870-f5w6fw6q 1998 2 - - JJ cord-006870-f5w6fw6q 1998 3 arterial arterial JJ cord-006870-f5w6fw6q 1998 4 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 1998 5 ( ( -LRB- cord-006870-f5w6fw6q 1998 6 IAT IAT NNP cord-006870-f5w6fw6q 1998 7 ) ) -RRB- cord-006870-f5w6fw6q 1998 8 has have VBZ cord-006870-f5w6fw6q 1998 9 been be VBN cord-006870-f5w6fw6q 1998 10 approved approve VBN cord-006870-f5w6fw6q 1998 11 for for IN cord-006870-f5w6fw6q 1998 12 acute acute JJ cord-006870-f5w6fw6q 1998 13 treatment treatment NN cord-006870-f5w6fw6q 1998 14 of of IN cord-006870-f5w6fw6q 1998 15 ischemic ischemic JJ cord-006870-f5w6fw6q 1998 16 strokes stroke NNS cord-006870-f5w6fw6q 1998 17 ( ( -LRB- cord-006870-f5w6fw6q 1998 18 IS be VBZ cord-006870-f5w6fw6q 1998 19 ) ) -RRB- cord-006870-f5w6fw6q 1998 20 . . . cord-006870-f5w6fw6q 1999 1 With with IN cord-006870-f5w6fw6q 1999 2 the the DT cord-006870-f5w6fw6q 1999 3 advent advent NN cord-006870-f5w6fw6q 1999 4 of of IN cord-006870-f5w6fw6q 1999 5 several several JJ cord-006870-f5w6fw6q 1999 6 new new JJ cord-006870-f5w6fw6q 1999 7 devices device NNS cord-006870-f5w6fw6q 1999 8 for for IN cord-006870-f5w6fw6q 1999 9 IAT IAT NNP cord-006870-f5w6fw6q 1999 10 , , , cord-006870-f5w6fw6q 1999 11 this this DT cord-006870-f5w6fw6q 1999 12 procedure procedure NN cord-006870-f5w6fw6q 1999 13 has have VBZ cord-006870-f5w6fw6q 1999 14 become become VBN cord-006870-f5w6fw6q 1999 15 more more RBR cord-006870-f5w6fw6q 1999 16 widely widely RB cord-006870-f5w6fw6q 1999 17 utilized utilize VBN cord-006870-f5w6fw6q 1999 18 with with IN cord-006870-f5w6fw6q 1999 19 better well JJR cord-006870-f5w6fw6q 1999 20 outcomes outcome NNS cord-006870-f5w6fw6q 1999 21 . . . cord-006870-f5w6fw6q 2000 1 We -PRON- PRP cord-006870-f5w6fw6q 2000 2 performed perform VBD cord-006870-f5w6fw6q 2000 3 this this DT cord-006870-f5w6fw6q 2000 4 analysis analysis NN cord-006870-f5w6fw6q 2000 5 to to TO cord-006870-f5w6fw6q 2000 6 evaluate evaluate VB cord-006870-f5w6fw6q 2000 7 trends trend NNS cord-006870-f5w6fw6q 2000 8 and and CC cord-006870-f5w6fw6q 2000 9 predictors predictor NNS cord-006870-f5w6fw6q 2000 10 of of IN cord-006870-f5w6fw6q 2000 11 utilization utilization NN cord-006870-f5w6fw6q 2000 12 of of IN cord-006870-f5w6fw6q 2000 13 IAT IAT NNP cord-006870-f5w6fw6q 2000 14 over over IN cord-006870-f5w6fw6q 2000 15 an an DT cord-006870-f5w6fw6q 2000 16 8 8 CD cord-006870-f5w6fw6q 2000 17 year year NN cord-006870-f5w6fw6q 2000 18 period period NN cord-006870-f5w6fw6q 2000 19 . . . cord-006870-f5w6fw6q 2001 1 Analysis analysis NN cord-006870-f5w6fw6q 2001 2 of of IN cord-006870-f5w6fw6q 2001 3 Nationwide Nationwide NNP cord-006870-f5w6fw6q 2001 4 Inpatient Inpatient NNP cord-006870-f5w6fw6q 2001 5 Sample Sample NNP cord-006870-f5w6fw6q 2001 6 data datum NNS cord-006870-f5w6fw6q 2001 7 ( ( -LRB- cord-006870-f5w6fw6q 2001 8 2006 2006 CD cord-006870-f5w6fw6q 2001 9 to to IN cord-006870-f5w6fw6q 2001 10 2013 2013 CD cord-006870-f5w6fw6q 2001 11 ) ) -RRB- cord-006870-f5w6fw6q 2001 12 showed show VBD cord-006870-f5w6fw6q 2001 13 a a DT cord-006870-f5w6fw6q 2001 14 total total NN cord-006870-f5w6fw6q 2001 15 of of IN cord-006870-f5w6fw6q 2001 16 850,997 850,997 CD cord-006870-f5w6fw6q 2001 17 patients patient NNS cord-006870-f5w6fw6q 2001 18 discharged discharge VBN cord-006870-f5w6fw6q 2001 19 with with IN cord-006870-f5w6fw6q 2001 20 a a DT cord-006870-f5w6fw6q 2001 21 primary primary JJ cord-006870-f5w6fw6q 2001 22 diagnosis diagnosis NN cord-006870-f5w6fw6q 2001 23 of of IN cord-006870-f5w6fw6q 2001 24 IS IS NNP cord-006870-f5w6fw6q 2001 25 , , , cord-006870-f5w6fw6q 2001 26 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 2001 27 Code Code NNP cord-006870-f5w6fw6q 2001 28 433.xx 433.xx CD cord-006870-f5w6fw6q 2001 29 , , , cord-006870-f5w6fw6q 2001 30 and and CC cord-006870-f5w6fw6q 2001 31 434.xx 434.xx CD cord-006870-f5w6fw6q 2001 32 . . . cord-006870-f5w6fw6q 2002 1 IAT IAT NNP cord-006870-f5w6fw6q 2002 2 was be VBD cord-006870-f5w6fw6q 2002 3 ascertained ascertain VBN cord-006870-f5w6fw6q 2002 4 by by IN cord-006870-f5w6fw6q 2002 5 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 2002 6 procedure procedure NN cord-006870-f5w6fw6q 2002 7 code code NN cord-006870-f5w6fw6q 2002 8 39.74 39.74 CD cord-006870-f5w6fw6q 2002 9 . . . cord-006870-f5w6fw6q 2003 1 Independent independent JJ cord-006870-f5w6fw6q 2003 2 predictors predictor NNS cord-006870-f5w6fw6q 2003 3 of of IN cord-006870-f5w6fw6q 2003 4 IAT IAT NNP cord-006870-f5w6fw6q 2003 5 were be VBD cord-006870-f5w6fw6q 2003 6 studied study VBN cord-006870-f5w6fw6q 2003 7 using use VBG cord-006870-f5w6fw6q 2003 8 binary binary JJ cord-006870-f5w6fw6q 2003 9 logistic logistic JJ cord-006870-f5w6fw6q 2003 10 regression regression NN cord-006870-f5w6fw6q 2003 11 . . . cord-006870-f5w6fw6q 2004 1 The the DT cord-006870-f5w6fw6q 2004 2 predictors predictor NNS cord-006870-f5w6fw6q 2004 3 included include VBN cord-006870-f5w6fw6q 2004 4 in in IN cord-006870-f5w6fw6q 2004 5 the the DT cord-006870-f5w6fw6q 2004 6 model model NN cord-006870-f5w6fw6q 2004 7 were be VBD cord-006870-f5w6fw6q 2004 8 age age NN cord-006870-f5w6fw6q 2004 9 , , , cord-006870-f5w6fw6q 2004 10 sex sex NN cord-006870-f5w6fw6q 2004 11 , , , cord-006870-f5w6fw6q 2004 12 race race NN cord-006870-f5w6fw6q 2004 13 , , , cord-006870-f5w6fw6q 2004 14 teaching teaching NN cord-006870-f5w6fw6q 2004 15 status status NN cord-006870-f5w6fw6q 2004 16 , , , cord-006870-f5w6fw6q 2004 17 and and CC cord-006870-f5w6fw6q 2004 18 insurance insurance NN cord-006870-f5w6fw6q 2004 19 type type NN cord-006870-f5w6fw6q 2004 20 . . . cord-006870-f5w6fw6q 2005 1 Results result NNS cord-006870-f5w6fw6q 2005 2 4903 4903 CD cord-006870-f5w6fw6q 2005 3 or or CC cord-006870-f5w6fw6q 2005 4 0.6 0.6 CD cord-006870-f5w6fw6q 2005 5 % % NN cord-006870-f5w6fw6q 2005 6 of of IN cord-006870-f5w6fw6q 2005 7 IS IS NNP cord-006870-f5w6fw6q 2005 8 patients patient NNS cord-006870-f5w6fw6q 2005 9 received receive VBD cord-006870-f5w6fw6q 2005 10 IAT IAT NNP cord-006870-f5w6fw6q 2005 11 . . . cord-006870-f5w6fw6q 2006 1 Mean mean JJ cord-006870-f5w6fw6q 2006 2 age age NN cord-006870-f5w6fw6q 2006 3 of of IN cord-006870-f5w6fw6q 2006 4 patients patient NNS cord-006870-f5w6fw6q 2006 5 receiving receive VBG cord-006870-f5w6fw6q 2006 6 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 2006 7 was be VBD cord-006870-f5w6fw6q 2006 8 71.01 71.01 CD cord-006870-f5w6fw6q 2006 9 years year NNS cord-006870-f5w6fw6q 2006 10 . . . cord-006870-f5w6fw6q 2007 1 Percentage percentage NN cord-006870-f5w6fw6q 2007 2 of of IN cord-006870-f5w6fw6q 2007 3 IS is NN cord-006870-f5w6fw6q 2007 4 patients patient NNS cord-006870-f5w6fw6q 2007 5 receiving receive VBG cord-006870-f5w6fw6q 2007 6 IAT IAT NNP cord-006870-f5w6fw6q 2007 7 has have VBZ cord-006870-f5w6fw6q 2007 8 consistently consistently RB cord-006870-f5w6fw6q 2007 9 increased increase VBN cord-006870-f5w6fw6q 2007 10 from from IN cord-006870-f5w6fw6q 2007 11 0.037 0.037 CD cord-006870-f5w6fw6q 2007 12 % % NN cord-006870-f5w6fw6q 2007 13 in in IN cord-006870-f5w6fw6q 2007 14 2006 2006 CD cord-006870-f5w6fw6q 2007 15 to to IN cord-006870-f5w6fw6q 2007 16 1 1 CD cord-006870-f5w6fw6q 2007 17 % % NN cord-006870-f5w6fw6q 2007 18 in in IN cord-006870-f5w6fw6q 2007 19 2013 2013 CD cord-006870-f5w6fw6q 2007 20 . . . cord-006870-f5w6fw6q 2008 1 We -PRON- PRP cord-006870-f5w6fw6q 2008 2 also also RB cord-006870-f5w6fw6q 2008 3 observed observe VBD cord-006870-f5w6fw6q 2008 4 significant significant JJ cord-006870-f5w6fw6q 2008 5 year year NN cord-006870-f5w6fw6q 2008 6 to to IN cord-006870-f5w6fw6q 2008 7 year year NN cord-006870-f5w6fw6q 2008 8 decrease decrease NN cord-006870-f5w6fw6q 2008 9 in in IN cord-006870-f5w6fw6q 2008 10 mortality mortality NN cord-006870-f5w6fw6q 2008 11 among among IN cord-006870-f5w6fw6q 2008 12 patients patient NNS cord-006870-f5w6fw6q 2008 13 receiving receive VBG cord-006870-f5w6fw6q 2008 14 IAT IAT NNP cord-006870-f5w6fw6q 2008 15 . . . cord-006870-f5w6fw6q 2009 1 In in IN cord-006870-f5w6fw6q 2009 2 2006 2006 CD cord-006870-f5w6fw6q 2009 3 , , , cord-006870-f5w6fw6q 2009 4 26.2 26.2 CD cord-006870-f5w6fw6q 2009 5 % % NN cord-006870-f5w6fw6q 2009 6 of of IN cord-006870-f5w6fw6q 2009 7 IAT IAT NNP cord-006870-f5w6fw6q 2009 8 patients patient NNS cord-006870-f5w6fw6q 2009 9 died die VBD cord-006870-f5w6fw6q 2009 10 as as IN cord-006870-f5w6fw6q 2009 11 compared compare VBN cord-006870-f5w6fw6q 2009 12 to to IN cord-006870-f5w6fw6q 2009 13 15.8 15.8 CD cord-006870-f5w6fw6q 2009 14 % % NN cord-006870-f5w6fw6q 2009 15 in in IN cord-006870-f5w6fw6q 2009 16 2013 2013 CD cord-006870-f5w6fw6q 2009 17 . . . cord-006870-f5w6fw6q 2010 1 Using use VBG cord-006870-f5w6fw6q 2010 2 binary binary JJ cord-006870-f5w6fw6q 2010 3 logistic logistic JJ cord-006870-f5w6fw6q 2010 4 regression regression NN cord-006870-f5w6fw6q 2010 5 , , , cord-006870-f5w6fw6q 2010 6 the the DT cord-006870-f5w6fw6q 2010 7 statistically statistically RB cord-006870-f5w6fw6q 2010 8 significant significant JJ cord-006870-f5w6fw6q 2010 9 independent independent JJ cord-006870-f5w6fw6q 2010 10 predictors predictor NNS cord-006870-f5w6fw6q 2010 11 of of IN cord-006870-f5w6fw6q 2010 12 IAT IAT NNP cord-006870-f5w6fw6q 2010 13 utilization utilization NN cord-006870-f5w6fw6q 2010 14 were be VBD cord-006870-f5w6fw6q 2010 15 Age age NN cord-006870-f5w6fw6q 2010 16 ( ( -LRB- cord-006870-f5w6fw6q 2010 17 OR= OR= NNP cord-006870-f5w6fw6q 2010 18 0.978 0.978 CD cord-006870-f5w6fw6q 2010 19 , , , cord-006870-f5w6fw6q 2010 20 p=0.000 p=0.000 NNP cord-006870-f5w6fw6q 2010 21 ) ) -RRB- cord-006870-f5w6fw6q 2010 22 , , , cord-006870-f5w6fw6q 2010 23 Female female JJ cord-006870-f5w6fw6q 2010 24 gender gender NN cord-006870-f5w6fw6q 2011 1 ( ( -LRB- cord-006870-f5w6fw6q 2011 2 OR=1.120 OR=1.120 NNP cord-006870-f5w6fw6q 2011 3 , , , cord-006870-f5w6fw6q 2011 4 p=0.019 p=0.019 NNP cord-006870-f5w6fw6q 2011 5 ) ) -RRB- cord-006870-f5w6fw6q 2011 6 , , , cord-006870-f5w6fw6q 2011 7 Insurance insurance NN cord-006870-f5w6fw6q 2011 8 type type NN cord-006870-f5w6fw6q 2011 9 as as IN cord-006870-f5w6fw6q 2011 10 compared compare VBN cord-006870-f5w6fw6q 2011 11 to to IN cord-006870-f5w6fw6q 2011 12 Medicare Medicare NNP cord-006870-f5w6fw6q 2011 13 ( ( -LRB- cord-006870-f5w6fw6q 2011 14 Private private JJ cord-006870-f5w6fw6q 2011 15 insurance insurance NN cord-006870-f5w6fw6q 2012 1 OR=1.199 OR=1.199 NNP cord-006870-f5w6fw6q 2013 1 p=0.006 p=0.006 NNS cord-006870-f5w6fw6q 2013 2 , , , cord-006870-f5w6fw6q 2013 3 and and CC cord-006870-f5w6fw6q 2013 4 self self NN cord-006870-f5w6fw6q 2013 5 - - HYPH cord-006870-f5w6fw6q 2013 6 pay pay NN cord-006870-f5w6fw6q 2013 7 OR=0.778 OR=0.778 NNS cord-006870-f5w6fw6q 2013 8 p=0.05 p=0.05 JJ cord-006870-f5w6fw6q 2013 9 ) ) -RRB- cord-006870-f5w6fw6q 2013 10 . . . cord-006870-f5w6fw6q 2014 1 As as IN cord-006870-f5w6fw6q 2014 2 compared compare VBN cord-006870-f5w6fw6q 2014 3 to to IN cord-006870-f5w6fw6q 2014 4 Caucasians Caucasians NNPS cord-006870-f5w6fw6q 2014 5 , , , cord-006870-f5w6fw6q 2014 6 African African NNPS cord-006870-f5w6fw6q 2014 7 Americans Americans NNPS cord-006870-f5w6fw6q 2014 8 were be VBD cord-006870-f5w6fw6q 2014 9 less less RBR cord-006870-f5w6fw6q 2014 10 likely likely JJ cord-006870-f5w6fw6q 2014 11 to to TO cord-006870-f5w6fw6q 2014 12 receive receive VB cord-006870-f5w6fw6q 2014 13 treatment treatment NN cord-006870-f5w6fw6q 2014 14 ( ( -LRB- cord-006870-f5w6fw6q 2014 15 OR=0.531 or=0.531 NN cord-006870-f5w6fw6q 2015 1 p=0.000 p=0.000 NNP cord-006870-f5w6fw6q 2015 2 ) ) -RRB- cord-006870-f5w6fw6q 2015 3 . . . cord-006870-f5w6fw6q 2016 1 Also also RB cord-006870-f5w6fw6q 2016 2 , , , cord-006870-f5w6fw6q 2016 3 a a DT cord-006870-f5w6fw6q 2016 4 teaching teaching NN cord-006870-f5w6fw6q 2016 5 hospital hospital NN cord-006870-f5w6fw6q 2016 6 was be VBD cord-006870-f5w6fw6q 2016 7 found find VBN cord-006870-f5w6fw6q 2016 8 to to TO cord-006870-f5w6fw6q 2016 9 be be VB cord-006870-f5w6fw6q 2016 10 more more RBR cord-006870-f5w6fw6q 2016 11 likely likely JJ cord-006870-f5w6fw6q 2016 12 to to TO cord-006870-f5w6fw6q 2016 13 administer administer VB cord-006870-f5w6fw6q 2016 14 IAT IAT NNP cord-006870-f5w6fw6q 2016 15 as as IN cord-006870-f5w6fw6q 2016 16 compared compare VBN cord-006870-f5w6fw6q 2016 17 to to IN cord-006870-f5w6fw6q 2016 18 a a DT cord-006870-f5w6fw6q 2016 19 non non JJ cord-006870-f5w6fw6q 2016 20 - - JJ cord-006870-f5w6fw6q 2016 21 teaching teaching JJ cord-006870-f5w6fw6q 2016 22 hospital hospital NN cord-006870-f5w6fw6q 2016 23 ( ( -LRB- cord-006870-f5w6fw6q 2016 24 OR or CC cord-006870-f5w6fw6q 2016 25 = = SYM cord-006870-f5w6fw6q 2016 26 5.941 5.941 CD cord-006870-f5w6fw6q 2016 27 , , , cord-006870-f5w6fw6q 2016 28 p=0.000 p=0.000 NNP cord-006870-f5w6fw6q 2016 29 ) ) -RRB- cord-006870-f5w6fw6q 2016 30 . . . cord-006870-f5w6fw6q 2017 1 IS be VBZ cord-006870-f5w6fw6q 2017 2 patients patient NNS cord-006870-f5w6fw6q 2017 3 with with IN cord-006870-f5w6fw6q 2017 4 younger young JJR cord-006870-f5w6fw6q 2017 5 age age NN cord-006870-f5w6fw6q 2017 6 , , , cord-006870-f5w6fw6q 2017 7 female female JJ cord-006870-f5w6fw6q 2017 8 gender gender NN cord-006870-f5w6fw6q 2017 9 , , , cord-006870-f5w6fw6q 2017 10 private private JJ cord-006870-f5w6fw6q 2017 11 insurance insurance NN cord-006870-f5w6fw6q 2017 12 and and CC cord-006870-f5w6fw6q 2017 13 patients patient NNS cord-006870-f5w6fw6q 2017 14 admitted admit VBN cord-006870-f5w6fw6q 2017 15 to to IN cord-006870-f5w6fw6q 2017 16 teaching teach VBG cord-006870-f5w6fw6q 2017 17 hospitals hospital NNS cord-006870-f5w6fw6q 2017 18 are be VBP cord-006870-f5w6fw6q 2017 19 more more RBR cord-006870-f5w6fw6q 2017 20 likely likely JJ cord-006870-f5w6fw6q 2017 21 and and CC cord-006870-f5w6fw6q 2017 22 African african JJ cord-006870-f5w6fw6q 2017 23 Americans Americans NNPS cord-006870-f5w6fw6q 2017 24 are be VBP cord-006870-f5w6fw6q 2017 25 less less RBR cord-006870-f5w6fw6q 2017 26 likely likely JJ cord-006870-f5w6fw6q 2017 27 to to TO cord-006870-f5w6fw6q 2017 28 receive receive VB cord-006870-f5w6fw6q 2017 29 IAT IAT NNP cord-006870-f5w6fw6q 2017 30 . . . cord-006870-f5w6fw6q 2018 1 This this DT cord-006870-f5w6fw6q 2018 2 study study NN cord-006870-f5w6fw6q 2018 3 showed show VBD cord-006870-f5w6fw6q 2018 4 that that IN cord-006870-f5w6fw6q 2018 5 IAT IAT NNP cord-006870-f5w6fw6q 2018 6 utilization utilization NN cord-006870-f5w6fw6q 2018 7 has have VBZ cord-006870-f5w6fw6q 2018 8 increased increase VBN cord-006870-f5w6fw6q 2018 9 significantly significantly RB cord-006870-f5w6fw6q 2018 10 since since IN cord-006870-f5w6fw6q 2018 11 2006 2006 CD cord-006870-f5w6fw6q 2018 12 with with IN cord-006870-f5w6fw6q 2018 13 a a DT cord-006870-f5w6fw6q 2018 14 steep steep JJ cord-006870-f5w6fw6q 2018 15 decline decline NN cord-006870-f5w6fw6q 2018 16 in in IN cord-006870-f5w6fw6q 2018 17 the the DT cord-006870-f5w6fw6q 2018 18 in in IN cord-006870-f5w6fw6q 2018 19 - - HYPH cord-006870-f5w6fw6q 2018 20 hospital hospital NN cord-006870-f5w6fw6q 2018 21 mortality mortality NN cord-006870-f5w6fw6q 2018 22 . . . cord-006870-f5w6fw6q 2019 1 This this DT cord-006870-f5w6fw6q 2019 2 may may MD cord-006870-f5w6fw6q 2019 3 point point VB cord-006870-f5w6fw6q 2019 4 to to IN cord-006870-f5w6fw6q 2019 5 improved improve VBN cord-006870-f5w6fw6q 2019 6 IAT IAT NNP cord-006870-f5w6fw6q 2019 7 devices device NNS cord-006870-f5w6fw6q 2019 8 and and CC cord-006870-f5w6fw6q 2019 9 better well JJR cord-006870-f5w6fw6q 2019 10 patients patient NNS cord-006870-f5w6fw6q 2019 11 ' ' POS cord-006870-f5w6fw6q 2019 12 selection selection NN cord-006870-f5w6fw6q 2019 13 . . . cord-006870-f5w6fw6q 2020 1 Telestroke Telestroke NNP cord-006870-f5w6fw6q 2020 2 plays play VBZ cord-006870-f5w6fw6q 2020 3 an an DT cord-006870-f5w6fw6q 2020 4 integral integral JJ cord-006870-f5w6fw6q 2020 5 role role NN cord-006870-f5w6fw6q 2020 6 in in IN cord-006870-f5w6fw6q 2020 7 stroke stroke NN cord-006870-f5w6fw6q 2020 8 care care NN cord-006870-f5w6fw6q 2020 9 . . . cord-006870-f5w6fw6q 2021 1 Nationally nationally RB cord-006870-f5w6fw6q 2021 2 the the DT cord-006870-f5w6fw6q 2021 3 most most RBS cord-006870-f5w6fw6q 2021 4 common common JJ cord-006870-f5w6fw6q 2021 5 model model NN cord-006870-f5w6fw6q 2021 6 is be VBZ cord-006870-f5w6fw6q 2021 7 the the DT cord-006870-f5w6fw6q 2021 8 hub hub NN cord-006870-f5w6fw6q 2021 9 and and CC cord-006870-f5w6fw6q 2021 10 spoke speak VBD cord-006870-f5w6fw6q 2021 11 , , , cord-006870-f5w6fw6q 2021 12 which which WDT cord-006870-f5w6fw6q 2021 13 is be VBZ cord-006870-f5w6fw6q 2021 14 used use VBN cord-006870-f5w6fw6q 2021 15 at at IN cord-006870-f5w6fw6q 2021 16 our -PRON- PRP$ cord-006870-f5w6fw6q 2021 17 institution institution NN cord-006870-f5w6fw6q 2021 18 . . . cord-006870-f5w6fw6q 2022 1 Understanding Understanding NNP cord-006870-f5w6fw6q 2022 2 Telestroke Telestroke NNP cord-006870-f5w6fw6q 2022 3 's 's POS cord-006870-f5w6fw6q 2022 4 role role NN cord-006870-f5w6fw6q 2022 5 in in IN cord-006870-f5w6fw6q 2022 6 the the DT cord-006870-f5w6fw6q 2022 7 transfer transfer NN cord-006870-f5w6fw6q 2022 8 of of IN cord-006870-f5w6fw6q 2022 9 candidate candidate NN cord-006870-f5w6fw6q 2022 10 patients patient NNS cord-006870-f5w6fw6q 2022 11 for for IN cord-006870-f5w6fw6q 2022 12 endovascular endovascular JJ cord-006870-f5w6fw6q 2022 13 therapy therapy NN cord-006870-f5w6fw6q 2022 14 ( ( -LRB- cord-006870-f5w6fw6q 2022 15 ET ET NNP cord-006870-f5w6fw6q 2022 16 ) ) -RRB- cord-006870-f5w6fw6q 2022 17 is be VBZ cord-006870-f5w6fw6q 2022 18 critical critical JJ cord-006870-f5w6fw6q 2022 19 to to IN cord-006870-f5w6fw6q 2022 20 minimizing minimize VBG cord-006870-f5w6fw6q 2022 21 delays delay NNS cord-006870-f5w6fw6q 2022 22 . . . cord-006870-f5w6fw6q 2023 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2023 2 primary primary JJ cord-006870-f5w6fw6q 2023 3 objective objective NN cord-006870-f5w6fw6q 2023 4 was be VBD cord-006870-f5w6fw6q 2023 5 to to TO cord-006870-f5w6fw6q 2023 6 evaluate evaluate VB cord-006870-f5w6fw6q 2023 7 predictors predictor NNS cord-006870-f5w6fw6q 2023 8 of of IN cord-006870-f5w6fw6q 2023 9 transfer transfer NN cord-006870-f5w6fw6q 2023 10 delay delay NN cord-006870-f5w6fw6q 2023 11 . . . cord-006870-f5w6fw6q 2024 1 Patients patient NNS cord-006870-f5w6fw6q 2024 2 were be VBD cord-006870-f5w6fw6q 2024 3 selected select VBN cord-006870-f5w6fw6q 2024 4 from from IN cord-006870-f5w6fw6q 2024 5 the the DT cord-006870-f5w6fw6q 2024 6 Get get NN cord-006870-f5w6fw6q 2024 7 with with IN cord-006870-f5w6fw6q 2024 8 the the DT cord-006870-f5w6fw6q 2024 9 Guidelines Guidelines NNPS cord-006870-f5w6fw6q 2024 10 - - HYPH cord-006870-f5w6fw6q 2024 11 Stroke stroke NN cord-006870-f5w6fw6q 2024 12 registry registry NN cord-006870-f5w6fw6q 2024 13 who who WP cord-006870-f5w6fw6q 2024 14 were be VBD cord-006870-f5w6fw6q 2024 15 transferred transfer VBN cord-006870-f5w6fw6q 2024 16 to to IN cord-006870-f5w6fw6q 2024 17 MGH MGH NNP cord-006870-f5w6fw6q 2024 18 from from IN cord-006870-f5w6fw6q 2024 19 Jan Jan NNP cord-006870-f5w6fw6q 2024 20 2011 2011 CD cord-006870-f5w6fw6q 2024 21 to to IN cord-006870-f5w6fw6q 2024 22 Oct Oct NNP cord-006870-f5w6fw6q 2024 23 2015 2015 CD cord-006870-f5w6fw6q 2024 24 with with IN cord-006870-f5w6fw6q 2024 25 NIHSS>6 nihss>6 NN cord-006870-f5w6fw6q 2024 26 and and CC cord-006870-f5w6fw6q 2024 27 last last JJ cord-006870-f5w6fw6q 2024 28 known know VBN cord-006870-f5w6fw6q 2024 29 well<12h well<12h NNS cord-006870-f5w6fw6q 2024 30 on on IN cord-006870-f5w6fw6q 2024 31 MGH MGH NNP cord-006870-f5w6fw6q 2024 32 arrival arrival NN cord-006870-f5w6fw6q 2024 33 ( ( -LRB- cord-006870-f5w6fw6q 2024 34 n=618 n=618 NFP cord-006870-f5w6fw6q 2024 35 ) ) -RRB- cord-006870-f5w6fw6q 2024 36 . . . cord-006870-f5w6fw6q 2025 1 We -PRON- PRP cord-006870-f5w6fw6q 2025 2 excluded exclude VBD cord-006870-f5w6fw6q 2025 3 patients patient NNS cord-006870-f5w6fw6q 2025 4 for for IN cord-006870-f5w6fw6q 2025 5 whom whom WP cord-006870-f5w6fw6q 2025 6 we -PRON- PRP cord-006870-f5w6fw6q 2025 7 could could MD cord-006870-f5w6fw6q 2025 8 not not RB cord-006870-f5w6fw6q 2025 9 calculate calculate VB cord-006870-f5w6fw6q 2025 10 transfer transfer NN cord-006870-f5w6fw6q 2025 11 time time NN cord-006870-f5w6fw6q 2025 12 ( ( -LRB- cord-006870-f5w6fw6q 2025 13 the the DT cord-006870-f5w6fw6q 2025 14 MGH MGH NNP cord-006870-f5w6fw6q 2025 15 arrival arrival NN cord-006870-f5w6fw6q 2025 16 time time NN cord-006870-f5w6fw6q 2025 17 minus minus IN cord-006870-f5w6fw6q 2025 18 the the DT cord-006870-f5w6fw6q 2025 19 telestroke telestroke NNP cord-006870-f5w6fw6q 2025 20 consult consult NN cord-006870-f5w6fw6q 2025 21 answered answer VBN cord-006870-f5w6fw6q 2025 22 time time NN cord-006870-f5w6fw6q 2025 23 , , , cord-006870-f5w6fw6q 2025 24 n=384 n=384 NNP cord-006870-f5w6fw6q 2025 25 ) ) -RRB- cord-006870-f5w6fw6q 2025 26 . . . cord-006870-f5w6fw6q 2026 1 Ideal ideal JJ cord-006870-f5w6fw6q 2026 2 time time NN cord-006870-f5w6fw6q 2026 3 was be VBD cord-006870-f5w6fw6q 2026 4 calculated calculate VBN cord-006870-f5w6fw6q 2026 5 using use VBG cord-006870-f5w6fw6q 2026 6 Google Google NNP cord-006870-f5w6fw6q 2026 7 Maps Maps NNP cord-006870-f5w6fw6q 2026 8 incorporating incorporate VBG cord-006870-f5w6fw6q 2026 9 date date NN cord-006870-f5w6fw6q 2026 10 / / SYM cord-006870-f5w6fw6q 2026 11 time time NN cord-006870-f5w6fw6q 2026 12 information information NN cord-006870-f5w6fw6q 2026 13 for for IN cord-006870-f5w6fw6q 2026 14 ground ground NN cord-006870-f5w6fw6q 2026 15 transfers transfer NNS cord-006870-f5w6fw6q 2026 16 and and CC cord-006870-f5w6fw6q 2026 17 straight straight JJ cord-006870-f5w6fw6q 2026 18 line line NN cord-006870-f5w6fw6q 2026 19 distance distance NN cord-006870-f5w6fw6q 2026 20 at at IN cord-006870-f5w6fw6q 2026 21 130 130 CD cord-006870-f5w6fw6q 2026 22 mph mph NN cord-006870-f5w6fw6q 2026 23 for for IN cord-006870-f5w6fw6q 2026 24 helicopter helicopter NN cord-006870-f5w6fw6q 2026 25 transfers transfer NNS cord-006870-f5w6fw6q 2026 26 . . . cord-006870-f5w6fw6q 2027 1 Ideal ideal JJ cord-006870-f5w6fw6q 2027 2 time time NN cord-006870-f5w6fw6q 2027 3 was be VBD cord-006870-f5w6fw6q 2027 4 subtracted subtract VBN cord-006870-f5w6fw6q 2027 5 from from IN cord-006870-f5w6fw6q 2027 6 actual actual JJ cord-006870-f5w6fw6q 2027 7 time time NN cord-006870-f5w6fw6q 2027 8 to to TO cord-006870-f5w6fw6q 2027 9 calculate calculate VB cord-006870-f5w6fw6q 2027 10 delay delay NN cord-006870-f5w6fw6q 2027 11 , , , cord-006870-f5w6fw6q 2027 12 accounting account VBG cord-006870-f5w6fw6q 2027 13 for for IN cord-006870-f5w6fw6q 2027 14 distance distance NN cord-006870-f5w6fw6q 2027 15 , , , cord-006870-f5w6fw6q 2027 16 mode mode NN cord-006870-f5w6fw6q 2027 17 of of IN cord-006870-f5w6fw6q 2027 18 transport transport NN cord-006870-f5w6fw6q 2027 19 , , , cord-006870-f5w6fw6q 2027 20 weather weather NN cord-006870-f5w6fw6q 2027 21 , , , cord-006870-f5w6fw6q 2027 22 and and CC cord-006870-f5w6fw6q 2027 23 traffic traffic NN cord-006870-f5w6fw6q 2027 24 . . . cord-006870-f5w6fw6q 2028 1 Analysis analysis NN cord-006870-f5w6fw6q 2028 2 of of IN cord-006870-f5w6fw6q 2028 3 covariance covariance NN cord-006870-f5w6fw6q 2028 4 was be VBD cord-006870-f5w6fw6q 2028 5 used use VBN cord-006870-f5w6fw6q 2028 6 to to TO cord-006870-f5w6fw6q 2028 7 explore explore VB cord-006870-f5w6fw6q 2028 8 3 3 CD cord-006870-f5w6fw6q 2028 9 possible possible JJ cord-006870-f5w6fw6q 2028 10 predictors predictor NNS cord-006870-f5w6fw6q 2028 11 of of IN cord-006870-f5w6fw6q 2028 12 delay delay NN cord-006870-f5w6fw6q 2028 13 ( ( -LRB- cord-006870-f5w6fw6q 2028 14 night night NN cord-006870-f5w6fw6q 2028 15 vs. vs. IN cord-006870-f5w6fw6q 2028 16 day day NN cord-006870-f5w6fw6q 2028 17 , , , cord-006870-f5w6fw6q 2028 18 weekend weekend NN cord-006870-f5w6fw6q 2028 19 vs. vs. IN cord-006870-f5w6fw6q 2028 20 weekday weekday NN cord-006870-f5w6fw6q 2028 21 , , , cord-006870-f5w6fw6q 2028 22 tPA tPA NNP cord-006870-f5w6fw6q 2028 23 delivery delivery NN cord-006870-f5w6fw6q 2028 24 at at IN cord-006870-f5w6fw6q 2028 25 spoke speak VBD cord-006870-f5w6fw6q 2028 26 ) ) -RRB- cord-006870-f5w6fw6q 2028 27 . . . cord-006870-f5w6fw6q 2029 1 Of of IN cord-006870-f5w6fw6q 2029 2 the the DT cord-006870-f5w6fw6q 2029 3 234 234 CD cord-006870-f5w6fw6q 2029 4 patients patient NNS cord-006870-f5w6fw6q 2029 5 in in IN cord-006870-f5w6fw6q 2029 6 the the DT cord-006870-f5w6fw6q 2029 7 study study NN cord-006870-f5w6fw6q 2029 8 , , , cord-006870-f5w6fw6q 2029 9 120 120 CD cord-006870-f5w6fw6q 2029 10 ( ( -LRB- cord-006870-f5w6fw6q 2029 11 51 51 CD cord-006870-f5w6fw6q 2029 12 % % NN cord-006870-f5w6fw6q 2029 13 ) ) -RRB- cord-006870-f5w6fw6q 2029 14 were be VBD cord-006870-f5w6fw6q 2029 15 transferred transfer VBN cord-006870-f5w6fw6q 2029 16 by by IN cord-006870-f5w6fw6q 2029 17 ambulance ambulance NN cord-006870-f5w6fw6q 2029 18 , , , cord-006870-f5w6fw6q 2029 19 114 114 CD cord-006870-f5w6fw6q 2029 20 ( ( -LRB- cord-006870-f5w6fw6q 2029 21 49 49 CD cord-006870-f5w6fw6q 2029 22 % % NN cord-006870-f5w6fw6q 2029 23 ) ) -RRB- cord-006870-f5w6fw6q 2029 24 by by IN cord-006870-f5w6fw6q 2029 25 helicopter helicopter NN cord-006870-f5w6fw6q 2029 26 , , , cord-006870-f5w6fw6q 2029 27 and and CC cord-006870-f5w6fw6q 2029 28 63 63 CD cord-006870-f5w6fw6q 2029 29 underwent undergo VBD cord-006870-f5w6fw6q 2029 30 ET ET NNP cord-006870-f5w6fw6q 2029 31 . . . cord-006870-f5w6fw6q 2030 1 A a DT cord-006870-f5w6fw6q 2030 2 significant significant JJ cord-006870-f5w6fw6q 2030 3 proportion proportion NN cord-006870-f5w6fw6q 2030 4 of of IN cord-006870-f5w6fw6q 2030 5 the the DT cord-006870-f5w6fw6q 2030 6 variation variation NN cord-006870-f5w6fw6q 2030 7 in in IN cord-006870-f5w6fw6q 2030 8 delay delay NN cord-006870-f5w6fw6q 2030 9 was be VBD cord-006870-f5w6fw6q 2030 10 explained explain VBN cord-006870-f5w6fw6q 2030 11 by by IN cord-006870-f5w6fw6q 2030 12 the the DT cord-006870-f5w6fw6q 2030 13 predictors predictor NNS cord-006870-f5w6fw6q 2030 14 ( ( -LRB- cord-006870-f5w6fw6q 2030 15 F=6.43 F=6.43 NNP cord-006870-f5w6fw6q 2030 16 , , , cord-006870-f5w6fw6q 2030 17 p<0.0005 p<0.0005 NN cord-006870-f5w6fw6q 2030 18 ) ) -RRB- cord-006870-f5w6fw6q 2030 19 . . . cord-006870-f5w6fw6q 2031 1 Nocturnal nocturnal JJ cord-006870-f5w6fw6q 2031 2 transfer transfer NN cord-006870-f5w6fw6q 2031 3 ( ( -LRB- cord-006870-f5w6fw6q 2031 4 1800 1800 CD cord-006870-f5w6fw6q 2031 5 - - HYPH cord-006870-f5w6fw6q 2031 6 0600hrs 0600hrs CD cord-006870-f5w6fw6q 2031 7 ) ) -RRB- cord-006870-f5w6fw6q 2031 8 was be VBD cord-006870-f5w6fw6q 2031 9 associated associate VBN cord-006870-f5w6fw6q 2031 10 with with IN cord-006870-f5w6fw6q 2031 11 significantly significantly RB cord-006870-f5w6fw6q 2031 12 longer long JJR cord-006870-f5w6fw6q 2031 13 delay delay NN cord-006870-f5w6fw6q 2031 14 ( ( -LRB- cord-006870-f5w6fw6q 2031 15 20.53 20.53 CD cord-006870-f5w6fw6q 2031 16 additional additional JJ cord-006870-f5w6fw6q 2031 17 minutes minute NNS cord-006870-f5w6fw6q 2031 18 relative relative JJ cord-006870-f5w6fw6q 2031 19 to to IN cord-006870-f5w6fw6q 2031 20 daytime daytime JJ cord-006870-f5w6fw6q 2031 21 transfers transfer NNS cord-006870-f5w6fw6q 2031 22 , , , cord-006870-f5w6fw6q 2031 23 p<0.0005 p<0.0005 NN cord-006870-f5w6fw6q 2031 24 ) ) -RRB- cord-006870-f5w6fw6q 2031 25 . . . cord-006870-f5w6fw6q 2032 1 Weekend weekend NN cord-006870-f5w6fw6q 2032 2 vs. vs. IN cord-006870-f5w6fw6q 2032 3 weekday weekday NN cord-006870-f5w6fw6q 2032 4 transfer transfer NN cord-006870-f5w6fw6q 2032 5 and and CC cord-006870-f5w6fw6q 2032 6 tPA tPA NNP cord-006870-f5w6fw6q 2032 7 delivery delivery NN cord-006870-f5w6fw6q 2032 8 at at IN cord-006870-f5w6fw6q 2032 9 spoke speak VBD cord-006870-f5w6fw6q 2032 10 hospital hospital NN cord-006870-f5w6fw6q 2032 11 did do VBD cord-006870-f5w6fw6q 2032 12 not not RB cord-006870-f5w6fw6q 2032 13 contribute contribute VB cord-006870-f5w6fw6q 2032 14 significantly significantly RB cord-006870-f5w6fw6q 2032 15 to to TO cord-006870-f5w6fw6q 2032 16 model model VB cord-006870-f5w6fw6q 2032 17 variance variance NN cord-006870-f5w6fw6q 2032 18 . . . cord-006870-f5w6fw6q 2033 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2033 2 findings finding NNS cord-006870-f5w6fw6q 2033 3 highlight highlight VBP cord-006870-f5w6fw6q 2033 4 the the DT cord-006870-f5w6fw6q 2033 5 importance importance NN cord-006870-f5w6fw6q 2033 6 of of IN cord-006870-f5w6fw6q 2033 7 refining refining NN cord-006870-f5w6fw6q 2033 8 protocol protocol NN cord-006870-f5w6fw6q 2033 9 approaches approach NNS cord-006870-f5w6fw6q 2033 10 . . . cord-006870-f5w6fw6q 2034 1 Nocturnal nocturnal JJ cord-006870-f5w6fw6q 2034 2 transfers transfer NNS cord-006870-f5w6fw6q 2034 3 were be VBD cord-006870-f5w6fw6q 2034 4 associated associate VBN cord-006870-f5w6fw6q 2034 5 with with IN cord-006870-f5w6fw6q 2034 6 substantial substantial JJ cord-006870-f5w6fw6q 2034 7 delay delay NN cord-006870-f5w6fw6q 2034 8 relative relative NN cord-006870-f5w6fw6q 2034 9 to to IN cord-006870-f5w6fw6q 2034 10 daytime daytime JJ cord-006870-f5w6fw6q 2034 11 transfers transfer NNS cord-006870-f5w6fw6q 2034 12 . . . cord-006870-f5w6fw6q 2035 1 In in IN cord-006870-f5w6fw6q 2035 2 contrast contrast NN cord-006870-f5w6fw6q 2035 3 , , , cord-006870-f5w6fw6q 2035 4 delivery delivery NN cord-006870-f5w6fw6q 2035 5 of of IN cord-006870-f5w6fw6q 2035 6 tPA tPA NNP cord-006870-f5w6fw6q 2035 7 was be VBD cord-006870-f5w6fw6q 2035 8 not not RB cord-006870-f5w6fw6q 2035 9 associated associate VBN cord-006870-f5w6fw6q 2035 10 with with IN cord-006870-f5w6fw6q 2035 11 delays delay NNS cord-006870-f5w6fw6q 2035 12 , , , cord-006870-f5w6fw6q 2035 13 underscoring underscore VBG cord-006870-f5w6fw6q 2035 14 the the DT cord-006870-f5w6fw6q 2035 15 impact impact NN cord-006870-f5w6fw6q 2035 16 of of IN cord-006870-f5w6fw6q 2035 17 effective effective JJ cord-006870-f5w6fw6q 2035 18 protocols protocol NNS cord-006870-f5w6fw6q 2035 19 that that WDT cord-006870-f5w6fw6q 2035 20 are be VBP cord-006870-f5w6fw6q 2035 21 in in IN cord-006870-f5w6fw6q 2035 22 place place NN cord-006870-f5w6fw6q 2035 23 . . . cord-006870-f5w6fw6q 2036 1 Metrics metric NNS cord-006870-f5w6fw6q 2036 2 and and CC cord-006870-f5w6fw6q 2036 3 protocols protocol NNS cord-006870-f5w6fw6q 2036 4 for for IN cord-006870-f5w6fw6q 2036 5 transfer transfer NN cord-006870-f5w6fw6q 2036 6 , , , cord-006870-f5w6fw6q 2036 7 especially especially RB cord-006870-f5w6fw6q 2036 8 at at IN cord-006870-f5w6fw6q 2036 9 night night NN cord-006870-f5w6fw6q 2036 10 , , , cord-006870-f5w6fw6q 2036 11 may may MD cord-006870-f5w6fw6q 2036 12 have have VB cord-006870-f5w6fw6q 2036 13 a a DT cord-006870-f5w6fw6q 2036 14 positive positive JJ cord-006870-f5w6fw6q 2036 15 impact impact NN cord-006870-f5w6fw6q 2036 16 on on IN cord-006870-f5w6fw6q 2036 17 transfer transfer NN cord-006870-f5w6fw6q 2036 18 times time NNS cord-006870-f5w6fw6q 2036 19 . . . cord-006870-f5w6fw6q 2037 1 The the DT cord-006870-f5w6fw6q 2037 2 use use NN cord-006870-f5w6fw6q 2037 3 of of IN cord-006870-f5w6fw6q 2037 4 anticoagulant anticoagulant JJ cord-006870-f5w6fw6q 2037 5 therapy therapy NN cord-006870-f5w6fw6q 2037 6 in in IN cord-006870-f5w6fw6q 2037 7 the the DT cord-006870-f5w6fw6q 2037 8 acute acute JJ cord-006870-f5w6fw6q 2037 9 stage stage NN cord-006870-f5w6fw6q 2037 10 of of IN cord-006870-f5w6fw6q 2037 11 ischemic ischemic JJ cord-006870-f5w6fw6q 2037 12 stroke stroke NN cord-006870-f5w6fw6q 2037 13 is be VBZ cord-006870-f5w6fw6q 2037 14 controversial controversial JJ cord-006870-f5w6fw6q 2037 15 . . . cord-006870-f5w6fw6q 2038 1 Novel novel JJ cord-006870-f5w6fw6q 2038 2 oral oral JJ cord-006870-f5w6fw6q 2038 3 anticoagulant anticoagulant NN cord-006870-f5w6fw6q 2038 4 ( ( -LRB- cord-006870-f5w6fw6q 2038 5 NOAC NOAC NNP cord-006870-f5w6fw6q 2038 6 ) ) -RRB- cord-006870-f5w6fw6q 2038 7 is be VBZ cord-006870-f5w6fw6q 2038 8 effective effective JJ cord-006870-f5w6fw6q 2038 9 in in IN cord-006870-f5w6fw6q 2038 10 preventing prevent VBG cord-006870-f5w6fw6q 2038 11 recurrent recurrent JJ cord-006870-f5w6fw6q 2038 12 embolism embolism NN cord-006870-f5w6fw6q 2038 13 in in IN cord-006870-f5w6fw6q 2038 14 patients patient NNS cord-006870-f5w6fw6q 2038 15 with with IN cord-006870-f5w6fw6q 2038 16 non non JJ cord-006870-f5w6fw6q 2038 17 - - JJ cord-006870-f5w6fw6q 2038 18 valvular valvular JJ cord-006870-f5w6fw6q 2038 19 atrial atrial JJ cord-006870-f5w6fw6q 2038 20 fibrillation fibrillation NN cord-006870-f5w6fw6q 2038 21 ( ( -LRB- cord-006870-f5w6fw6q 2038 22 NVAF NVAF NNP cord-006870-f5w6fw6q 2038 23 ) ) -RRB- cord-006870-f5w6fw6q 2038 24 , , , cord-006870-f5w6fw6q 2038 25 but but CC cord-006870-f5w6fw6q 2038 26 the the DT cord-006870-f5w6fw6q 2038 27 risk risk NN cord-006870-f5w6fw6q 2038 28 of of IN cord-006870-f5w6fw6q 2038 29 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 2038 30 transformation transformation NN cord-006870-f5w6fw6q 2038 31 is be VBZ cord-006870-f5w6fw6q 2038 32 the the DT cord-006870-f5w6fw6q 2038 33 major major JJ cord-006870-f5w6fw6q 2038 34 concern concern NN cord-006870-f5w6fw6q 2038 35 for for IN cord-006870-f5w6fw6q 2038 36 its -PRON- PRP$ cord-006870-f5w6fw6q 2038 37 early early JJ cord-006870-f5w6fw6q 2038 38 use use NN cord-006870-f5w6fw6q 2038 39 in in IN cord-006870-f5w6fw6q 2038 40 ischemic ischemic JJ cord-006870-f5w6fw6q 2038 41 stroke stroke NN cord-006870-f5w6fw6q 2038 42 . . . cord-006870-f5w6fw6q 2039 1 We -PRON- PRP cord-006870-f5w6fw6q 2039 2 aimed aim VBD cord-006870-f5w6fw6q 2039 3 to to TO cord-006870-f5w6fw6q 2039 4 study study VB cord-006870-f5w6fw6q 2039 5 the the DT cord-006870-f5w6fw6q 2039 6 use use NN cord-006870-f5w6fw6q 2039 7 of of IN cord-006870-f5w6fw6q 2039 8 NOAC NOAC NNP cord-006870-f5w6fw6q 2039 9 in in IN cord-006870-f5w6fw6q 2039 10 patients patient NNS cord-006870-f5w6fw6q 2039 11 with with IN cord-006870-f5w6fw6q 2039 12 acute acute JJ cord-006870-f5w6fw6q 2039 13 ischemic ischemic JJ cord-006870-f5w6fw6q 2039 14 stroke stroke NN cord-006870-f5w6fw6q 2039 15 and and CC cord-006870-f5w6fw6q 2039 16 NVAF NVAF NNP cord-006870-f5w6fw6q 2039 17 . . . cord-006870-f5w6fw6q 2040 1 Patients patient NNS cord-006870-f5w6fw6q 2040 2 with with IN cord-006870-f5w6fw6q 2040 3 acute acute JJ cord-006870-f5w6fw6q 2040 4 ischemic ischemic JJ cord-006870-f5w6fw6q 2040 5 stroke stroke NN cord-006870-f5w6fw6q 2040 6 and and CC cord-006870-f5w6fw6q 2040 7 NVAF NVAF NNP cord-006870-f5w6fw6q 2040 8 , , , cord-006870-f5w6fw6q 2040 9 who who WP cord-006870-f5w6fw6q 2040 10 were be VBD cord-006870-f5w6fw6q 2040 11 admitted admit VBN cord-006870-f5w6fw6q 2040 12 to to IN cord-006870-f5w6fw6q 2040 13 our -PRON- PRP$ cord-006870-f5w6fw6q 2040 14 acute acute JJ cord-006870-f5w6fw6q 2040 15 stroke stroke NN cord-006870-f5w6fw6q 2040 16 unit unit NN cord-006870-f5w6fw6q 2040 17 from from IN cord-006870-f5w6fw6q 2040 18 2014 2014 CD cord-006870-f5w6fw6q 2040 19 to to IN cord-006870-f5w6fw6q 2040 20 2016 2016 CD cord-006870-f5w6fw6q 2040 21 , , , cord-006870-f5w6fw6q 2040 22 were be VBD cord-006870-f5w6fw6q 2040 23 recruited recruit VBN cord-006870-f5w6fw6q 2040 24 in in IN cord-006870-f5w6fw6q 2040 25 this this DT cord-006870-f5w6fw6q 2040 26 single single JJ cord-006870-f5w6fw6q 2040 27 - - HYPH cord-006870-f5w6fw6q 2040 28 centre centre NN cord-006870-f5w6fw6q 2040 29 cohort cohort NN cord-006870-f5w6fw6q 2040 30 study study NN cord-006870-f5w6fw6q 2040 31 . . . cord-006870-f5w6fw6q 2041 1 The the DT cord-006870-f5w6fw6q 2041 2 timing timing NN cord-006870-f5w6fw6q 2041 3 of of IN cord-006870-f5w6fw6q 2041 4 initiation initiation NN cord-006870-f5w6fw6q 2041 5 of of IN cord-006870-f5w6fw6q 2041 6 NOAC NOAC NNP cord-006870-f5w6fw6q 2041 7 is be VBZ cord-006870-f5w6fw6q 2041 8 at at IN cord-006870-f5w6fw6q 2041 9 the the DT cord-006870-f5w6fw6q 2041 10 discretion discretion NN cord-006870-f5w6fw6q 2041 11 of of IN cord-006870-f5w6fw6q 2041 12 the the DT cord-006870-f5w6fw6q 2041 13 treating treat VBG cord-006870-f5w6fw6q 2041 14 physician physician NN cord-006870-f5w6fw6q 2041 15 based base VBN cord-006870-f5w6fw6q 2041 16 on on IN cord-006870-f5w6fw6q 2041 17 the the DT cord-006870-f5w6fw6q 2041 18 stroke stroke NN cord-006870-f5w6fw6q 2041 19 severity severity NN cord-006870-f5w6fw6q 2041 20 and and CC cord-006870-f5w6fw6q 2041 21 infarct infarct NN cord-006870-f5w6fw6q 2041 22 size size NN cord-006870-f5w6fw6q 2041 23 . . . cord-006870-f5w6fw6q 2042 1 NVAF NVAF NNP cord-006870-f5w6fw6q 2042 2 attributed attribute VBN cord-006870-f5w6fw6q 2042 3 to to IN cord-006870-f5w6fw6q 2042 4 32.5 32.5 CD cord-006870-f5w6fw6q 2042 5 % % NN cord-006870-f5w6fw6q 2042 6 ( ( -LRB- cord-006870-f5w6fw6q 2042 7 214/ 214/ CD cord-006870-f5w6fw6q 2042 8 659 659 CD cord-006870-f5w6fw6q 2042 9 ) ) -RRB- cord-006870-f5w6fw6q 2042 10 of of IN cord-006870-f5w6fw6q 2042 11 all all DT cord-006870-f5w6fw6q 2042 12 ischemic ischemic JJ cord-006870-f5w6fw6q 2042 13 stroke stroke NN cord-006870-f5w6fw6q 2042 14 cases case NNS cord-006870-f5w6fw6q 2042 15 . . . cord-006870-f5w6fw6q 2043 1 The the DT cord-006870-f5w6fw6q 2043 2 early early JJ cord-006870-f5w6fw6q 2043 3 recurrent recurrent JJ cord-006870-f5w6fw6q 2043 4 embolism embolism NN cord-006870-f5w6fw6q 2043 5 rates rate NNS cord-006870-f5w6fw6q 2043 6 were be VBD cord-006870-f5w6fw6q 2043 7 1.4 1.4 CD cord-006870-f5w6fw6q 2043 8 % % NN cord-006870-f5w6fw6q 2043 9 , , , cord-006870-f5w6fw6q 2043 10 3.3 3.3 CD cord-006870-f5w6fw6q 2043 11 % % NN cord-006870-f5w6fw6q 2043 12 and and CC cord-006870-f5w6fw6q 2043 13 4.7 4.7 CD cord-006870-f5w6fw6q 2043 14 % % NN cord-006870-f5w6fw6q 2043 15 at at IN cord-006870-f5w6fw6q 2043 16 one one CD cord-006870-f5w6fw6q 2043 17 week week NN cord-006870-f5w6fw6q 2043 18 , , , cord-006870-f5w6fw6q 2043 19 two two CD cord-006870-f5w6fw6q 2043 20 weeks week NNS cord-006870-f5w6fw6q 2043 21 and and CC cord-006870-f5w6fw6q 2043 22 one one CD cord-006870-f5w6fw6q 2043 23 month month NN cord-006870-f5w6fw6q 2043 24 respectively respectively RB cord-006870-f5w6fw6q 2043 25 . . . cord-006870-f5w6fw6q 2044 1 NOACs noac NNS cord-006870-f5w6fw6q 2044 2 were be VBD cord-006870-f5w6fw6q 2044 3 prescribed prescribe VBN cord-006870-f5w6fw6q 2044 4 in in IN cord-006870-f5w6fw6q 2044 5 105 105 CD cord-006870-f5w6fw6q 2044 6 patients patient NNS cord-006870-f5w6fw6q 2044 7 . . . cord-006870-f5w6fw6q 2045 1 NOACs noac NNS cord-006870-f5w6fw6q 2045 2 were be VBD cord-006870-f5w6fw6q 2045 3 initiated initiate VBN cord-006870-f5w6fw6q 2045 4 within within IN cord-006870-f5w6fw6q 2045 5 one one CD cord-006870-f5w6fw6q 2045 6 week week NN cord-006870-f5w6fw6q 2045 7 in in IN cord-006870-f5w6fw6q 2045 8 47 47 CD cord-006870-f5w6fw6q 2045 9 patients patient NNS cord-006870-f5w6fw6q 2045 10 ( ( -LRB- cord-006870-f5w6fw6q 2045 11 44.8 44.8 CD cord-006870-f5w6fw6q 2045 12 % % NN cord-006870-f5w6fw6q 2045 13 ) ) -RRB- cord-006870-f5w6fw6q 2045 14 . . . cord-006870-f5w6fw6q 2046 1 The the DT cord-006870-f5w6fw6q 2046 2 median median JJ cord-006870-f5w6fw6q 2046 3 time time NN cord-006870-f5w6fw6q 2046 4 to to IN cord-006870-f5w6fw6q 2046 5 NOAC NOAC NNP cord-006870-f5w6fw6q 2046 6 initiation initiation NN cord-006870-f5w6fw6q 2046 7 were be VBD cord-006870-f5w6fw6q 2046 8 five five CD cord-006870-f5w6fw6q 2046 9 days day NNS cord-006870-f5w6fw6q 2046 10 ( ( -LRB- cord-006870-f5w6fw6q 2046 11 IQR IQR NNP cord-006870-f5w6fw6q 2046 12 1.8 1.8 CD cord-006870-f5w6fw6q 2046 13 -18.0 -18.0 CD cord-006870-f5w6fw6q 2046 14 ) ) -RRB- cord-006870-f5w6fw6q 2046 15 , , , cord-006870-f5w6fw6q 2046 16 nine nine CD cord-006870-f5w6fw6q 2046 17 days day NNS cord-006870-f5w6fw6q 2046 18 ( ( -LRB- cord-006870-f5w6fw6q 2046 19 IQR IQR NNP cord-006870-f5w6fw6q 2046 20 6.3 6.3 CD cord-006870-f5w6fw6q 2046 21 -25.3 -25.3 CD cord-006870-f5w6fw6q 2046 22 ) ) -RRB- cord-006870-f5w6fw6q 2046 23 and and CC cord-006870-f5w6fw6q 2046 24 20 20 CD cord-006870-f5w6fw6q 2046 25 days day NNS cord-006870-f5w6fw6q 2046 26 ( ( -LRB- cord-006870-f5w6fw6q 2046 27 IQR IQR NNP cord-006870-f5w6fw6q 2046 28 12.0 12.0 CD cord-006870-f5w6fw6q 2046 29 -37.0 -37.0 NFP cord-006870-f5w6fw6q 2046 30 ) ) -RRB- cord-006870-f5w6fw6q 2046 31 for for IN cord-006870-f5w6fw6q 2046 32 patients patient NNS cord-006870-f5w6fw6q 2046 33 with with IN cord-006870-f5w6fw6q 2046 34 no no DT cord-006870-f5w6fw6q 2046 35 / / SYM cord-006870-f5w6fw6q 2046 36 small small JJ cord-006870-f5w6fw6q 2046 37 - - HYPH cord-006870-f5w6fw6q 2046 38 sized sized JJ cord-006870-f5w6fw6q 2046 39 infarct infarct NN cord-006870-f5w6fw6q 2046 40 , , , cord-006870-f5w6fw6q 2046 41 moderate moderate JJ cord-006870-f5w6fw6q 2046 42 - - HYPH cord-006870-f5w6fw6q 2046 43 sized sized JJ cord-006870-f5w6fw6q 2046 44 infarct infarct NN cord-006870-f5w6fw6q 2046 45 , , , cord-006870-f5w6fw6q 2046 46 and and CC cord-006870-f5w6fw6q 2046 47 large large JJ cord-006870-f5w6fw6q 2046 48 - - HYPH cord-006870-f5w6fw6q 2046 49 sized sized JJ cord-006870-f5w6fw6q 2046 50 infarct infarct NN cord-006870-f5w6fw6q 2046 51 respectively respectively RB cord-006870-f5w6fw6q 2046 52 . . . cord-006870-f5w6fw6q 2047 1 At at IN cord-006870-f5w6fw6q 2047 2 one one CD cord-006870-f5w6fw6q 2047 3 month month NN cord-006870-f5w6fw6q 2047 4 , , , cord-006870-f5w6fw6q 2047 5 two two CD cord-006870-f5w6fw6q 2047 6 patients patient NNS cord-006870-f5w6fw6q 2047 7 had have VBD cord-006870-f5w6fw6q 2047 8 recurrent recurrent JJ cord-006870-f5w6fw6q 2047 9 ischemic ischemic JJ cord-006870-f5w6fw6q 2047 10 stroke stroke NN cord-006870-f5w6fw6q 2047 11 despite despite IN cord-006870-f5w6fw6q 2047 12 treated treat VBN cord-006870-f5w6fw6q 2047 13 with with IN cord-006870-f5w6fw6q 2047 14 NOAC NOAC NNP cord-006870-f5w6fw6q 2047 15 . . . cord-006870-f5w6fw6q 2048 1 Only only RB cord-006870-f5w6fw6q 2048 2 one one CD cord-006870-f5w6fw6q 2048 3 patient patient NN cord-006870-f5w6fw6q 2048 4 , , , cord-006870-f5w6fw6q 2048 5 who who WP cord-006870-f5w6fw6q 2048 6 had have VBD cord-006870-f5w6fw6q 2048 7 a a DT cord-006870-f5w6fw6q 2048 8 large large JJ cord-006870-f5w6fw6q 2048 9 - - HYPH cord-006870-f5w6fw6q 2048 10 sized sized JJ cord-006870-f5w6fw6q 2048 11 infarct infarct NN cord-006870-f5w6fw6q 2048 12 , , , cord-006870-f5w6fw6q 2048 13 developed develop VBD cord-006870-f5w6fw6q 2048 14 symptomatic symptomatic JJ cord-006870-f5w6fw6q 2048 15 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 2048 16 transformation transformation NN cord-006870-f5w6fw6q 2048 17 . . . cord-006870-f5w6fw6q 2049 1 Early early JJ cord-006870-f5w6fw6q 2049 2 use use NN cord-006870-f5w6fw6q 2049 3 of of IN cord-006870-f5w6fw6q 2049 4 NOAC NOAC NNP cord-006870-f5w6fw6q 2049 5 in in IN cord-006870-f5w6fw6q 2049 6 ischemic ischemic JJ cord-006870-f5w6fw6q 2049 7 stroke stroke NN cord-006870-f5w6fw6q 2049 8 appears appear VBZ cord-006870-f5w6fw6q 2049 9 to to TO cord-006870-f5w6fw6q 2049 10 be be VB cord-006870-f5w6fw6q 2049 11 safe safe JJ cord-006870-f5w6fw6q 2049 12 . . . cord-006870-f5w6fw6q 2050 1 Further further JJ cord-006870-f5w6fw6q 2050 2 large large JJ cord-006870-f5w6fw6q 2050 3 prospective prospective JJ cord-006870-f5w6fw6q 2050 4 studies study NNS cord-006870-f5w6fw6q 2050 5 are be VBP cord-006870-f5w6fw6q 2050 6 required require VBN cord-006870-f5w6fw6q 2050 7 to to TO cord-006870-f5w6fw6q 2050 8 evaluate evaluate VB cord-006870-f5w6fw6q 2050 9 the the DT cord-006870-f5w6fw6q 2050 10 risk risk NN cord-006870-f5w6fw6q 2050 11 and and CC cord-006870-f5w6fw6q 2050 12 benefit benefit NN cord-006870-f5w6fw6q 2050 13 of of IN cord-006870-f5w6fw6q 2050 14 NOAC NOAC NNP cord-006870-f5w6fw6q 2050 15 use use NN cord-006870-f5w6fw6q 2050 16 in in IN cord-006870-f5w6fw6q 2050 17 acute acute JJ cord-006870-f5w6fw6q 2050 18 ischemic ischemic JJ cord-006870-f5w6fw6q 2050 19 stroke stroke NN cord-006870-f5w6fw6q 2050 20 . . . cord-006870-f5w6fw6q 2051 1 Osmotherapy Osmotherapy NNP cord-006870-f5w6fw6q 2051 2 ( ( -LRB- cord-006870-f5w6fw6q 2051 3 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2051 4 saline saline NN cord-006870-f5w6fw6q 2051 5 or or CC cord-006870-f5w6fw6q 2051 6 mannitol mannitol NN cord-006870-f5w6fw6q 2051 7 ) ) -RRB- cord-006870-f5w6fw6q 2051 8 is be VBZ cord-006870-f5w6fw6q 2051 9 the the DT cord-006870-f5w6fw6q 2051 10 mainstay mainstay NN cord-006870-f5w6fw6q 2051 11 of of IN cord-006870-f5w6fw6q 2051 12 available available JJ cord-006870-f5w6fw6q 2051 13 therapy therapy NN cord-006870-f5w6fw6q 2051 14 to to TO cord-006870-f5w6fw6q 2051 15 counter counter VB cord-006870-f5w6fw6q 2051 16 cerebral cerebral JJ cord-006870-f5w6fw6q 2051 17 edema edema NN cord-006870-f5w6fw6q 2051 18 that that WDT cord-006870-f5w6fw6q 2051 19 can can MD cord-006870-f5w6fw6q 2051 20 develop develop VB cord-006870-f5w6fw6q 2051 21 after after IN cord-006870-f5w6fw6q 2051 22 large large JJ cord-006870-f5w6fw6q 2051 23 hemispheric hemispheric JJ cord-006870-f5w6fw6q 2051 24 infarction infarction NN cord-006870-f5w6fw6q 2051 25 . . . cord-006870-f5w6fw6q 2052 1 In in IN cord-006870-f5w6fw6q 2052 2 a a DT cord-006870-f5w6fw6q 2052 3 post post JJ cord-006870-f5w6fw6q 2052 4 - - JJ cord-006870-f5w6fw6q 2052 5 hoc hoc JJ cord-006870-f5w6fw6q 2052 6 analysis analysis NN cord-006870-f5w6fw6q 2052 7 of of IN cord-006870-f5w6fw6q 2052 8 the the DT cord-006870-f5w6fw6q 2052 9 GAMES games NN cord-006870-f5w6fw6q 2052 10 - - HYPH cord-006870-f5w6fw6q 2052 11 RP RP NNP cord-006870-f5w6fw6q 2052 12 trial trial NN cord-006870-f5w6fw6q 2052 13 , , , cord-006870-f5w6fw6q 2052 14 we -PRON- PRP cord-006870-f5w6fw6q 2052 15 hypothesized hypothesize VBD cord-006870-f5w6fw6q 2052 16 that that IN cord-006870-f5w6fw6q 2052 17 patients patient NNS cord-006870-f5w6fw6q 2052 18 with with IN cord-006870-f5w6fw6q 2052 19 large large JJ cord-006870-f5w6fw6q 2052 20 infarction infarction NN cord-006870-f5w6fw6q 2052 21 , , , cord-006870-f5w6fw6q 2052 22 treated treat VBN cord-006870-f5w6fw6q 2052 23 with with IN cord-006870-f5w6fw6q 2052 24 intravenous intravenous JJ cord-006870-f5w6fw6q 2052 25 glyburide glyburide NN cord-006870-f5w6fw6q 2052 26 , , , cord-006870-f5w6fw6q 2052 27 might may MD cord-006870-f5w6fw6q 2052 28 require require VB cord-006870-f5w6fw6q 2052 29 less less JJR cord-006870-f5w6fw6q 2052 30 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 2052 31 than than IN cord-006870-f5w6fw6q 2052 32 placebo placebo NN cord-006870-f5w6fw6q 2052 33 treated treat VBN cord-006870-f5w6fw6q 2052 34 patients patient NNS cord-006870-f5w6fw6q 2052 35 . . . cord-006870-f5w6fw6q 2053 1 GAMES games NN cord-006870-f5w6fw6q 2053 2 - - HYPH cord-006870-f5w6fw6q 2053 3 RP RP NNP cord-006870-f5w6fw6q 2053 4 was be VBD cord-006870-f5w6fw6q 2053 5 a a DT cord-006870-f5w6fw6q 2053 6 multi multi JJ cord-006870-f5w6fw6q 2053 7 - - JJ cord-006870-f5w6fw6q 2053 8 center center JJ cord-006870-f5w6fw6q 2053 9 prospective prospective NN cord-006870-f5w6fw6q 2053 10 , , , cord-006870-f5w6fw6q 2053 11 double double JJ cord-006870-f5w6fw6q 2053 12 blind blind JJ cord-006870-f5w6fw6q 2053 13 , , , cord-006870-f5w6fw6q 2053 14 randomized randomized JJ cord-006870-f5w6fw6q 2053 15 , , , cord-006870-f5w6fw6q 2053 16 placebo placebo NN cord-006870-f5w6fw6q 2053 17 controlled control VBN cord-006870-f5w6fw6q 2053 18 study study NN cord-006870-f5w6fw6q 2053 19 which which WDT cord-006870-f5w6fw6q 2053 20 enrolled enrol VBD cord-006870-f5w6fw6q 2053 21 84 84 CD cord-006870-f5w6fw6q 2053 22 patients patient NNS cord-006870-f5w6fw6q 2053 23 with with IN cord-006870-f5w6fw6q 2053 24 large large JJ cord-006870-f5w6fw6q 2053 25 anterior anterior JJ cord-006870-f5w6fw6q 2053 26 circulation circulation NN cord-006870-f5w6fw6q 2053 27 infarction infarction NN cord-006870-f5w6fw6q 2053 28 . . . cord-006870-f5w6fw6q 2054 1 Patients patient NNS cord-006870-f5w6fw6q 2054 2 were be VBD cord-006870-f5w6fw6q 2054 3 randomized randomize VBN cord-006870-f5w6fw6q 2054 4 to to IN cord-006870-f5w6fw6q 2054 5 IV IV NNP cord-006870-f5w6fw6q 2054 6 glyburide glyburide NNP cord-006870-f5w6fw6q 2054 7 administration administration NN cord-006870-f5w6fw6q 2054 8 ( ( -LRB- cord-006870-f5w6fw6q 2054 9 BIIB093 BIIB093 NNP cord-006870-f5w6fw6q 2054 10 ; ; : cord-006870-f5w6fw6q 2054 11 n=44 n=44 NN cord-006870-f5w6fw6q 2054 12 ) ) -RRB- cord-006870-f5w6fw6q 2054 13 or or CC cord-006870-f5w6fw6q 2054 14 placebo placebo NN cord-006870-f5w6fw6q 2054 15 ( ( -LRB- cord-006870-f5w6fw6q 2054 16 n=40 n=40 JJ cord-006870-f5w6fw6q 2054 17 ) ) -RRB- cord-006870-f5w6fw6q 2054 18 with with IN cord-006870-f5w6fw6q 2054 19 target target NN cord-006870-f5w6fw6q 2054 20 time time NN cord-006870-f5w6fw6q 2054 21 from from IN cord-006870-f5w6fw6q 2054 22 symptom symptom NN cord-006870-f5w6fw6q 2054 23 onset onset NN cord-006870-f5w6fw6q 2054 24 to to IN cord-006870-f5w6fw6q 2054 25 drug drug NN cord-006870-f5w6fw6q 2054 26 infusion infusion NN cord-006870-f5w6fw6q 2054 27 decompressive decompressive NNP cord-006870-f5w6fw6q 2054 28 craniectomy craniectomy NNP cord-006870-f5w6fw6q 2054 29 ( ( -LRB- cord-006870-f5w6fw6q 2054 30 DC DC NNP cord-006870-f5w6fw6q 2054 31 ) ) -RRB- cord-006870-f5w6fw6q 2054 32 , , , cord-006870-f5w6fw6q 2054 33 or or CC cord-006870-f5w6fw6q 2054 34 both both DT cord-006870-f5w6fw6q 2054 35 . . . cord-006870-f5w6fw6q 2055 1 Total total JJ cord-006870-f5w6fw6q 2055 2 bolus bolus NN cord-006870-f5w6fw6q 2055 3 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 2055 4 dosing dosing NN cord-006870-f5w6fw6q 2055 5 was be VBD cord-006870-f5w6fw6q 2055 6 quantified quantify VBN cord-006870-f5w6fw6q 2055 7 by by IN cord-006870-f5w6fw6q 2055 8 an an DT cord-006870-f5w6fw6q 2055 9 " " `` cord-006870-f5w6fw6q 2055 10 osmolar osmolar JJ cord-006870-f5w6fw6q 2055 11 load load NN cord-006870-f5w6fw6q 2055 12 " " '' cord-006870-f5w6fw6q 2055 13 ( ( -LRB- cord-006870-f5w6fw6q 2055 14 volume volume NN cord-006870-f5w6fw6q 2055 15 in in IN cord-006870-f5w6fw6q 2055 16 L L NNP cord-006870-f5w6fw6q 2055 17 * * NFP cord-006870-f5w6fw6q 2055 18 osmolarity osmolarity NN cord-006870-f5w6fw6q 2055 19 in in IN cord-006870-f5w6fw6q 2055 20 mOsm mOsm NNP cord-006870-f5w6fw6q 2055 21 / / SYM cord-006870-f5w6fw6q 2055 22 L L NNP cord-006870-f5w6fw6q 2055 23 ) ) -RRB- cord-006870-f5w6fw6q 2055 24 . . . cord-006870-f5w6fw6q 2056 1 Of of IN cord-006870-f5w6fw6q 2056 2 the the DT cord-006870-f5w6fw6q 2056 3 84 84 CD cord-006870-f5w6fw6q 2056 4 subjects subject NNS cord-006870-f5w6fw6q 2056 5 , , , cord-006870-f5w6fw6q 2056 6 the the DT cord-006870-f5w6fw6q 2056 7 percentage percentage NN cord-006870-f5w6fw6q 2056 8 of of IN cord-006870-f5w6fw6q 2056 9 patients patient NNS cord-006870-f5w6fw6q 2056 10 who who WP cord-006870-f5w6fw6q 2056 11 received receive VBD cord-006870-f5w6fw6q 2056 12 bolus bolus NN cord-006870-f5w6fw6q 2056 13 osmotherapy osmotherapy NNP cord-006870-f5w6fw6q 2056 14 did do VBD cord-006870-f5w6fw6q 2056 15 not not RB cord-006870-f5w6fw6q 2056 16 differ differ VB cord-006870-f5w6fw6q 2056 17 between between IN cord-006870-f5w6fw6q 2056 18 the the DT cord-006870-f5w6fw6q 2056 19 glyburide glyburide NN cord-006870-f5w6fw6q 2056 20 and and CC cord-006870-f5w6fw6q 2056 21 placebo placebo NN cord-006870-f5w6fw6q 2056 22 treated treat VBN cord-006870-f5w6fw6q 2056 23 subjects subject NNS cord-006870-f5w6fw6q 2056 24 ( ( -LRB- cord-006870-f5w6fw6q 2056 25 51 51 CD cord-006870-f5w6fw6q 2056 26 % % NN cord-006870-f5w6fw6q 2056 27 v. v. CC cord-006870-f5w6fw6q 2056 28 53 53 CD cord-006870-f5w6fw6q 2056 29 % % NN cord-006870-f5w6fw6q 2056 30 ; ; , cord-006870-f5w6fw6q 2056 31 p=0.89 p=0.89 NNP cord-006870-f5w6fw6q 2056 32 ) ) -RRB- cord-006870-f5w6fw6q 2056 33 . . . cord-006870-f5w6fw6q 2057 1 There there EX cord-006870-f5w6fw6q 2057 2 was be VBD cord-006870-f5w6fw6q 2057 3 no no DT cord-006870-f5w6fw6q 2057 4 difference difference NN cord-006870-f5w6fw6q 2057 5 in in IN cord-006870-f5w6fw6q 2057 6 mean mean JJ cord-006870-f5w6fw6q 2057 7 total total JJ cord-006870-f5w6fw6q 2057 8 osmolar osmolar JJ cord-006870-f5w6fw6q 2057 9 load load NN cord-006870-f5w6fw6q 2057 10 received receive VBN cord-006870-f5w6fw6q 2057 11 ( ( -LRB- cord-006870-f5w6fw6q 2057 12 mOsm mOsm NNP cord-006870-f5w6fw6q 2057 13 ) ) -RRB- cord-006870-f5w6fw6q 2057 14 or or CC cord-006870-f5w6fw6q 2057 15 hours hour NNS cord-006870-f5w6fw6q 2057 16 from from IN cord-006870-f5w6fw6q 2057 17 drug drug NN cord-006870-f5w6fw6q 2057 18 bolus bolus NN cord-006870-f5w6fw6q 2057 19 to to IN cord-006870-f5w6fw6q 2057 20 osmotherapy osmotherapy NNP cord-006870-f5w6fw6q 2057 21 administration administration NNP cord-006870-f5w6fw6q 2057 22 . . . cord-006870-f5w6fw6q 2058 1 Overall overall RB cord-006870-f5w6fw6q 2058 2 , , , cord-006870-f5w6fw6q 2058 3 40 40 CD cord-006870-f5w6fw6q 2058 4 subjects subject NNS cord-006870-f5w6fw6q 2058 5 received receive VBD cord-006870-f5w6fw6q 2058 6 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 2058 7 . . . cord-006870-f5w6fw6q 2059 1 The the DT cord-006870-f5w6fw6q 2059 2 baseline baseline JJ cord-006870-f5w6fw6q 2059 3 DWI DWI NNP cord-006870-f5w6fw6q 2059 4 lesion lesion NN cord-006870-f5w6fw6q 2059 5 volume volume NN cord-006870-f5w6fw6q 2059 6 ( ( -LRB- cord-006870-f5w6fw6q 2059 7 mL ml NN cord-006870-f5w6fw6q 2059 8 ) ) -RRB- cord-006870-f5w6fw6q 2059 9 was be VBD cord-006870-f5w6fw6q 2059 10 significantly significantly RB cord-006870-f5w6fw6q 2059 11 larger large JJR cord-006870-f5w6fw6q 2059 12 in in IN cord-006870-f5w6fw6q 2059 13 the the DT cord-006870-f5w6fw6q 2059 14 osmotherapy osmotherapy NNP cord-006870-f5w6fw6q 2059 15 treated treat VBN cord-006870-f5w6fw6q 2059 16 group group NN cord-006870-f5w6fw6q 2059 17 ( ( -LRB- cord-006870-f5w6fw6q 2059 18 170.2 170.2 CD cord-006870-f5w6fw6q 2059 19 ±53.3 ±53.3 CD cord-006870-f5w6fw6q 2059 20 v. v. CC cord-006870-f5w6fw6q 2059 21 147.4 147.4 CD cord-006870-f5w6fw6q 2059 22 ±45.5 ±45.5 NN cord-006870-f5w6fw6q 2059 23 ; ; : cord-006870-f5w6fw6q 2059 24 p=0.047 p=0.047 NNS cord-006870-f5w6fw6q 2059 25 ) ) -RRB- cord-006870-f5w6fw6q 2059 26 . . . cord-006870-f5w6fw6q 2060 1 The the DT cord-006870-f5w6fw6q 2060 2 presence presence NN cord-006870-f5w6fw6q 2060 3 of of IN cord-006870-f5w6fw6q 2060 4 adjudicated adjudicate VBN cord-006870-f5w6fw6q 2060 5 malignant malignant JJ cord-006870-f5w6fw6q 2060 6 edema edema NN cord-006870-f5w6fw6q 2060 7 on on IN cord-006870-f5w6fw6q 2060 8 imaging imaging NN cord-006870-f5w6fw6q 2060 9 was be VBD cord-006870-f5w6fw6q 2060 10 more more RBR cord-006870-f5w6fw6q 2060 11 common common JJ cord-006870-f5w6fw6q 2060 12 in in IN cord-006870-f5w6fw6q 2060 13 the the DT cord-006870-f5w6fw6q 2060 14 osmotherapy osmotherapy NNP cord-006870-f5w6fw6q 2060 15 group group NNP cord-006870-f5w6fw6q 2060 16 ( ( -LRB- cord-006870-f5w6fw6q 2060 17 63 63 CD cord-006870-f5w6fw6q 2060 18 % % NN cord-006870-f5w6fw6q 2060 19 v. v. CC cord-006870-f5w6fw6q 2060 20 30 30 CD cord-006870-f5w6fw6q 2060 21 % % NN cord-006870-f5w6fw6q 2060 22 , , , cord-006870-f5w6fw6q 2060 23 p=0.004 p=0.004 NNP cord-006870-f5w6fw6q 2060 24 ) ) -RRB- cord-006870-f5w6fw6q 2060 25 , , , cord-006870-f5w6fw6q 2060 26 as as IN cord-006870-f5w6fw6q 2060 27 was be VBD cord-006870-f5w6fw6q 2060 28 DC DC NNP cord-006870-f5w6fw6q 2060 29 ( ( -LRB- cord-006870-f5w6fw6q 2060 30 45 45 CD cord-006870-f5w6fw6q 2060 31 % % NN cord-006870-f5w6fw6q 2060 32 v. v. CC cord-006870-f5w6fw6q 2060 33 8 8 CD cord-006870-f5w6fw6q 2060 34 % % NN cord-006870-f5w6fw6q 2060 35 ; ; , cord-006870-f5w6fw6q 2060 36 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 2060 37 ) ) -RRB- cord-006870-f5w6fw6q 2060 38 . . . cord-006870-f5w6fw6q 2061 1 Among among IN cord-006870-f5w6fw6q 2061 2 patients patient NNS cord-006870-f5w6fw6q 2061 3 with with IN cord-006870-f5w6fw6q 2061 4 adjudicated adjudicate VBN cord-006870-f5w6fw6q 2061 5 clinical clinical JJ cord-006870-f5w6fw6q 2061 6 neurologic neurologic JJ cord-006870-f5w6fw6q 2061 7 deterioration deterioration NN cord-006870-f5w6fw6q 2061 8 from from IN cord-006870-f5w6fw6q 2061 9 edema edema NN cord-006870-f5w6fw6q 2061 10 , , , cord-006870-f5w6fw6q 2061 11 31 31 CD cord-006870-f5w6fw6q 2061 12 % % NN cord-006870-f5w6fw6q 2061 13 ( ( -LRB- cord-006870-f5w6fw6q 2061 14 n=11 n=11 NNP cord-006870-f5w6fw6q 2061 15 ) ) -RRB- cord-006870-f5w6fw6q 2061 16 did do VBD cord-006870-f5w6fw6q 2061 17 not not RB cord-006870-f5w6fw6q 2061 18 receive receive VB cord-006870-f5w6fw6q 2061 19 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 2061 20 . . . cord-006870-f5w6fw6q 2062 1 Treatment treatment NN cord-006870-f5w6fw6q 2062 2 with with IN cord-006870-f5w6fw6q 2062 3 IV IV NNP cord-006870-f5w6fw6q 2062 4 glyburide glyburide NN cord-006870-f5w6fw6q 2062 5 was be VBD cord-006870-f5w6fw6q 2062 6 not not RB cord-006870-f5w6fw6q 2062 7 associated associate VBN cord-006870-f5w6fw6q 2062 8 with with IN cord-006870-f5w6fw6q 2062 9 less less JJR cord-006870-f5w6fw6q 2062 10 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 2062 11 , , , cord-006870-f5w6fw6q 2062 12 possibly possibly RB cord-006870-f5w6fw6q 2062 13 due due IN cord-006870-f5w6fw6q 2062 14 to to IN cord-006870-f5w6fw6q 2062 15 a a DT cord-006870-f5w6fw6q 2062 16 ceiling ceiling NN cord-006870-f5w6fw6q 2062 17 effect effect NN cord-006870-f5w6fw6q 2062 18 resulting result VBG cord-006870-f5w6fw6q 2062 19 from from IN cord-006870-f5w6fw6q 2062 20 the the DT cord-006870-f5w6fw6q 2062 21 large large JJ cord-006870-f5w6fw6q 2062 22 infarct infarct NN cord-006870-f5w6fw6q 2062 23 volumes volume NNS cord-006870-f5w6fw6q 2062 24 . . . cord-006870-f5w6fw6q 2063 1 However however RB cord-006870-f5w6fw6q 2063 2 , , , cord-006870-f5w6fw6q 2063 3 osmotherapy osmotherapy NNP cord-006870-f5w6fw6q 2063 4 use use NN cord-006870-f5w6fw6q 2063 5 was be VBD cord-006870-f5w6fw6q 2063 6 associated associate VBN cord-006870-f5w6fw6q 2063 7 with with IN cord-006870-f5w6fw6q 2063 8 larger large JJR cord-006870-f5w6fw6q 2063 9 infarct infarct NN cord-006870-f5w6fw6q 2063 10 volumes volume NNS cord-006870-f5w6fw6q 2063 11 , , , cord-006870-f5w6fw6q 2063 12 malignant malignant JJ cord-006870-f5w6fw6q 2063 13 edema edema NN cord-006870-f5w6fw6q 2063 14 , , , cord-006870-f5w6fw6q 2063 15 and and CC cord-006870-f5w6fw6q 2063 16 higher high JJR cord-006870-f5w6fw6q 2063 17 incidence incidence NN cord-006870-f5w6fw6q 2063 18 of of IN cord-006870-f5w6fw6q 2063 19 DC DC NNP cord-006870-f5w6fw6q 2063 20 . . . cord-006870-f5w6fw6q 2064 1 Use Use NNP cord-006870-f5w6fw6q 2064 2 of of IN cord-006870-f5w6fw6q 2064 3 osmotherapy osmotherapy NNP cord-006870-f5w6fw6q 2064 4 did do VBD cord-006870-f5w6fw6q 2064 5 not not RB cord-006870-f5w6fw6q 2064 6 always always RB cord-006870-f5w6fw6q 2064 7 follow follow VB cord-006870-f5w6fw6q 2064 8 the the DT cord-006870-f5w6fw6q 2064 9 appearance appearance NN cord-006870-f5w6fw6q 2064 10 of of IN cord-006870-f5w6fw6q 2064 11 clinical clinical JJ cord-006870-f5w6fw6q 2064 12 or or CC cord-006870-f5w6fw6q 2064 13 radiographic radiographic JJ cord-006870-f5w6fw6q 2064 14 malignant malignant JJ cord-006870-f5w6fw6q 2064 15 edema edema NN cord-006870-f5w6fw6q 2064 16 . . . cord-006870-f5w6fw6q 2065 1 Acute acute JJ cord-006870-f5w6fw6q 2065 2 ischemic ischemic JJ cord-006870-f5w6fw6q 2065 3 stroke stroke NN cord-006870-f5w6fw6q 2065 4 patients patient NNS cord-006870-f5w6fw6q 2065 5 receiving receive VBG cord-006870-f5w6fw6q 2065 6 intravenous intravenous JJ cord-006870-f5w6fw6q 2065 7 alteplase alteplase NN cord-006870-f5w6fw6q 2065 8 ( ( -LRB- cord-006870-f5w6fw6q 2065 9 IV IV NNP cord-006870-f5w6fw6q 2065 10 - - HYPH cord-006870-f5w6fw6q 2065 11 tPA tPA NNP cord-006870-f5w6fw6q 2065 12 ) ) -RRB- cord-006870-f5w6fw6q 2065 13 are be VBP cord-006870-f5w6fw6q 2065 14 placed place VBN cord-006870-f5w6fw6q 2065 15 on on IN cord-006870-f5w6fw6q 2065 16 bedrest bedrest NN cord-006870-f5w6fw6q 2065 17 for for IN cord-006870-f5w6fw6q 2065 18 24 24 CD cord-006870-f5w6fw6q 2065 19 hours hour NNS cord-006870-f5w6fw6q 2065 20 or or CC cord-006870-f5w6fw6q 2065 21 longer long JJR cord-006870-f5w6fw6q 2065 22 due due JJ cord-006870-f5w6fw6q 2065 23 to to IN cord-006870-f5w6fw6q 2065 24 provider provider NN cord-006870-f5w6fw6q 2065 25 fear fear NN cord-006870-f5w6fw6q 2065 26 of of IN cord-006870-f5w6fw6q 2065 27 worsening worsen VBG cord-006870-f5w6fw6q 2065 28 stroke stroke NN cord-006870-f5w6fw6q 2065 29 symptoms symptom NNS cord-006870-f5w6fw6q 2065 30 from from IN cord-006870-f5w6fw6q 2065 31 decreased decrease VBN cord-006870-f5w6fw6q 2065 32 cerebral cerebral JJ cord-006870-f5w6fw6q 2065 33 perfusion perfusion NN cord-006870-f5w6fw6q 2065 34 . . . cord-006870-f5w6fw6q 2066 1 This this DT cord-006870-f5w6fw6q 2066 2 is be VBZ cord-006870-f5w6fw6q 2066 3 based base VBN cord-006870-f5w6fw6q 2066 4 on on IN cord-006870-f5w6fw6q 2066 5 medical medical JJ cord-006870-f5w6fw6q 2066 6 uncertainty uncertainty NN cord-006870-f5w6fw6q 2066 7 and and CC cord-006870-f5w6fw6q 2066 8 lack lack NN cord-006870-f5w6fw6q 2066 9 of of IN cord-006870-f5w6fw6q 2066 10 robust robust JJ cord-006870-f5w6fw6q 2066 11 studies study NNS cord-006870-f5w6fw6q 2066 12 , , , cord-006870-f5w6fw6q 2066 13 despite despite IN cord-006870-f5w6fw6q 2066 14 American American NNP cord-006870-f5w6fw6q 2066 15 Stroke Stroke NNP cord-006870-f5w6fw6q 2066 16 Association Association NNP cord-006870-f5w6fw6q 2066 17 ( ( -LRB- cord-006870-f5w6fw6q 2066 18 ASA ASA NNP cord-006870-f5w6fw6q 2066 19 ) ) -RRB- cord-006870-f5w6fw6q 2066 20 recommendations recommendation NNS cord-006870-f5w6fw6q 2066 21 for for IN cord-006870-f5w6fw6q 2066 22 mobilization mobilization NN cord-006870-f5w6fw6q 2066 23 when when WRB cord-006870-f5w6fw6q 2066 24 hemodynamically hemodynamically RB cord-006870-f5w6fw6q 2066 25 stable stable JJ cord-006870-f5w6fw6q 2066 26 . . . cord-006870-f5w6fw6q 2067 1 This this DT cord-006870-f5w6fw6q 2067 2 retrospective retrospective JJ cord-006870-f5w6fw6q 2067 3 observational observational JJ cord-006870-f5w6fw6q 2067 4 study study NN cord-006870-f5w6fw6q 2067 5 evaluates evaluate VBZ cord-006870-f5w6fw6q 2067 6 very very RB cord-006870-f5w6fw6q 2067 7 early early JJ cord-006870-f5w6fw6q 2067 8 mobility mobility NN cord-006870-f5w6fw6q 2067 9 in in IN cord-006870-f5w6fw6q 2067 10 acute acute JJ cord-006870-f5w6fw6q 2067 11 ischemic ischemic JJ cord-006870-f5w6fw6q 2067 12 stroke stroke NN cord-006870-f5w6fw6q 2067 13 patients patient NNS cord-006870-f5w6fw6q 2067 14 post post VBP cord-006870-f5w6fw6q 2067 15 IV IV NNP cord-006870-f5w6fw6q 2067 16 - - HYPH cord-006870-f5w6fw6q 2067 17 tPA tPA NNP cord-006870-f5w6fw6q 2067 18 while while IN cord-006870-f5w6fw6q 2067 19 evaluating evaluate VBG cord-006870-f5w6fw6q 2067 20 for for IN cord-006870-f5w6fw6q 2067 21 change change NN cord-006870-f5w6fw6q 2067 22 in in IN cord-006870-f5w6fw6q 2067 23 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2067 24 . . . cord-006870-f5w6fw6q 2068 1 Medical medical JJ cord-006870-f5w6fw6q 2068 2 records record NNS cord-006870-f5w6fw6q 2068 3 of of IN cord-006870-f5w6fw6q 2068 4 ischemic ischemic JJ cord-006870-f5w6fw6q 2068 5 stroke stroke NN cord-006870-f5w6fw6q 2068 6 patients patient NNS cord-006870-f5w6fw6q 2068 7 who who WP cord-006870-f5w6fw6q 2068 8 received receive VBD cord-006870-f5w6fw6q 2068 9 IV IV NNP cord-006870-f5w6fw6q 2068 10 - - HYPH cord-006870-f5w6fw6q 2068 11 tPA tPA NNP cord-006870-f5w6fw6q 2068 12 between between IN cord-006870-f5w6fw6q 2068 13 2012 2012 CD cord-006870-f5w6fw6q 2068 14 and and CC cord-006870-f5w6fw6q 2068 15 2016 2016 CD cord-006870-f5w6fw6q 2068 16 at at IN cord-006870-f5w6fw6q 2068 17 two two CD cord-006870-f5w6fw6q 2068 18 urban urban JJ cord-006870-f5w6fw6q 2068 19 hospitals hospital NNS cord-006870-f5w6fw6q 2068 20 were be VBD cord-006870-f5w6fw6q 2068 21 reviewed review VBN cord-006870-f5w6fw6q 2068 22 for for IN cord-006870-f5w6fw6q 2068 23 mobility mobility NN cord-006870-f5w6fw6q 2068 24 protocol protocol NN cord-006870-f5w6fw6q 2068 25 activities activity NNS cord-006870-f5w6fw6q 2068 26 . . . cord-006870-f5w6fw6q 2069 1 Patients patient NNS cord-006870-f5w6fw6q 2069 2 who who WP cord-006870-f5w6fw6q 2069 3 were be VBD cord-006870-f5w6fw6q 2069 4 given give VBN cord-006870-f5w6fw6q 2069 5 endovascular endovascular JJ cord-006870-f5w6fw6q 2069 6 treatment treatment NN cord-006870-f5w6fw6q 2069 7 , , , cord-006870-f5w6fw6q 2069 8 placed place VBN cord-006870-f5w6fw6q 2069 9 on on IN cord-006870-f5w6fw6q 2069 10 comfort comfort NN cord-006870-f5w6fw6q 2069 11 care care NN cord-006870-f5w6fw6q 2069 12 on on IN cord-006870-f5w6fw6q 2069 13 day day NN cord-006870-f5w6fw6q 2069 14 zero zero CD cord-006870-f5w6fw6q 2069 15 or or CC cord-006870-f5w6fw6q 2069 16 one one CD cord-006870-f5w6fw6q 2069 17 , , , cord-006870-f5w6fw6q 2069 18 mobilized mobilize VBN cord-006870-f5w6fw6q 2069 19 after after IN cord-006870-f5w6fw6q 2069 20 the the DT cord-006870-f5w6fw6q 2069 21 first first JJ cord-006870-f5w6fw6q 2069 22 24 24 CD cord-006870-f5w6fw6q 2069 23 hours hour NNS cord-006870-f5w6fw6q 2069 24 , , , cord-006870-f5w6fw6q 2069 25 transferred transfer VBN cord-006870-f5w6fw6q 2069 26 out out RP cord-006870-f5w6fw6q 2069 27 or or CC cord-006870-f5w6fw6q 2069 28 left leave VBN cord-006870-f5w6fw6q 2069 29 against against IN cord-006870-f5w6fw6q 2069 30 medical medical JJ cord-006870-f5w6fw6q 2069 31 advice advice NN cord-006870-f5w6fw6q 2069 32 were be VBD cord-006870-f5w6fw6q 2069 33 excluded exclude VBN cord-006870-f5w6fw6q 2069 34 from from IN cord-006870-f5w6fw6q 2069 35 the the DT cord-006870-f5w6fw6q 2069 36 analysis analysis NN cord-006870-f5w6fw6q 2069 37 . . . cord-006870-f5w6fw6q 2070 1 Multiple multiple JJ cord-006870-f5w6fw6q 2070 2 linear linear JJ cord-006870-f5w6fw6q 2070 3 regression regression NN cord-006870-f5w6fw6q 2070 4 was be VBD cord-006870-f5w6fw6q 2070 5 used use VBN cord-006870-f5w6fw6q 2070 6 to to TO cord-006870-f5w6fw6q 2070 7 determine determine VB cord-006870-f5w6fw6q 2070 8 if if IN cord-006870-f5w6fw6q 2070 9 those those DT cord-006870-f5w6fw6q 2070 10 patients patient NNS cord-006870-f5w6fw6q 2070 11 mobilized mobilize VBD cord-006870-f5w6fw6q 2070 12 earlier early RBR cord-006870-f5w6fw6q 2070 13 saw see VBD cord-006870-f5w6fw6q 2070 14 a a DT cord-006870-f5w6fw6q 2070 15 greater great JJR cord-006870-f5w6fw6q 2070 16 change change NN cord-006870-f5w6fw6q 2070 17 between between IN cord-006870-f5w6fw6q 2070 18 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2070 19 at at IN cord-006870-f5w6fw6q 2070 20 admit admit NN cord-006870-f5w6fw6q 2070 21 and and CC cord-006870-f5w6fw6q 2070 22 24 24 CD cord-006870-f5w6fw6q 2070 23 hours hour NNS cord-006870-f5w6fw6q 2070 24 post post NN cord-006870-f5w6fw6q 2070 25 IV IV NNP cord-006870-f5w6fw6q 2070 26 - - HYPH cord-006870-f5w6fw6q 2070 27 tPA tPA NNP cord-006870-f5w6fw6q 2070 28 administration administration NN cord-006870-f5w6fw6q 2070 29 , , , cord-006870-f5w6fw6q 2070 30 adjusting adjust VBG cord-006870-f5w6fw6q 2070 31 for for IN cord-006870-f5w6fw6q 2070 32 age age NN cord-006870-f5w6fw6q 2070 33 and and CC cord-006870-f5w6fw6q 2070 34 gender gender NN cord-006870-f5w6fw6q 2070 35 . . . cord-006870-f5w6fw6q 2071 1 Of of IN cord-006870-f5w6fw6q 2071 2 the the DT cord-006870-f5w6fw6q 2071 3 268 268 CD cord-006870-f5w6fw6q 2071 4 patients patient NNS cord-006870-f5w6fw6q 2071 5 included include VBN cord-006870-f5w6fw6q 2071 6 in in IN cord-006870-f5w6fw6q 2071 7 the the DT cord-006870-f5w6fw6q 2071 8 final final JJ cord-006870-f5w6fw6q 2071 9 analysis analysis NN cord-006870-f5w6fw6q 2071 10 , , , cord-006870-f5w6fw6q 2071 11 46.6 46.6 CD cord-006870-f5w6fw6q 2071 12 % % NN cord-006870-f5w6fw6q 2071 13 ( ( -LRB- cord-006870-f5w6fw6q 2071 14 n=125 n=125 NNP cord-006870-f5w6fw6q 2071 15 ) ) -RRB- cord-006870-f5w6fw6q 2071 16 were be VBD cord-006870-f5w6fw6q 2071 17 female female JJ cord-006870-f5w6fw6q 2071 18 , , , cord-006870-f5w6fw6q 2071 19 mean mean JJ cord-006870-f5w6fw6q 2071 20 age age NN cord-006870-f5w6fw6q 2071 21 was be VBD cord-006870-f5w6fw6q 2071 22 68 68 CD cord-006870-f5w6fw6q 2071 23 . . . cord-006870-f5w6fw6q 2072 1 The the DT cord-006870-f5w6fw6q 2072 2 multiple multiple JJ cord-006870-f5w6fw6q 2072 3 linear linear JJ cord-006870-f5w6fw6q 2072 4 regression regression NN cord-006870-f5w6fw6q 2072 5 results result NNS cord-006870-f5w6fw6q 2072 6 showed show VBD cord-006870-f5w6fw6q 2072 7 no no DT cord-006870-f5w6fw6q 2072 8 significant significant JJ cord-006870-f5w6fw6q 2072 9 relationship relationship NN cord-006870-f5w6fw6q 2072 10 between between IN cord-006870-f5w6fw6q 2072 11 change change NN cord-006870-f5w6fw6q 2072 12 in in IN cord-006870-f5w6fw6q 2072 13 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2072 14 from from IN cord-006870-f5w6fw6q 2072 15 admit admit VB cord-006870-f5w6fw6q 2072 16 to to IN cord-006870-f5w6fw6q 2072 17 24 24 CD cord-006870-f5w6fw6q 2072 18 hours hour NNS cord-006870-f5w6fw6q 2072 19 post post NN cord-006870-f5w6fw6q 2072 20 IV IV NNP cord-006870-f5w6fw6q 2072 21 - - HYPH cord-006870-f5w6fw6q 2072 22 tPA tPA NNP cord-006870-f5w6fw6q 2072 23 and and CC cord-006870-f5w6fw6q 2072 24 earlier early JJR cord-006870-f5w6fw6q 2072 25 mobilization mobilization NN cord-006870-f5w6fw6q 2072 26 , , , cord-006870-f5w6fw6q 2072 27 after after IN cord-006870-f5w6fw6q 2072 28 adjusting adjust VBG cord-006870-f5w6fw6q 2072 29 for for IN cord-006870-f5w6fw6q 2072 30 age age NN cord-006870-f5w6fw6q 2072 31 and and CC cord-006870-f5w6fw6q 2072 32 gender gender NN cord-006870-f5w6fw6q 2072 33 ( ( -LRB- cord-006870-f5w6fw6q 2072 34 ß= ß= NFP cord-006870-f5w6fw6q 2072 35 -0.065 -0.065 NNP cord-006870-f5w6fw6q 2072 36 change change NN cord-006870-f5w6fw6q 2072 37 in in IN cord-006870-f5w6fw6q 2072 38 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2072 39 points point NNS cord-006870-f5w6fw6q 2072 40 per per IN cord-006870-f5w6fw6q 2072 41 hour hour NN cord-006870-f5w6fw6q 2072 42 ; ; : cord-006870-f5w6fw6q 2072 43 p=0.181 p=0.181 ADD cord-006870-f5w6fw6q 2072 44 ) ) -RRB- cord-006870-f5w6fw6q 2072 45 . . . cord-006870-f5w6fw6q 2073 1 This this DT cord-006870-f5w6fw6q 2073 2 study study NN cord-006870-f5w6fw6q 2073 3 reveals reveal VBZ cord-006870-f5w6fw6q 2073 4 early early JJ cord-006870-f5w6fw6q 2073 5 mobility mobility NN cord-006870-f5w6fw6q 2073 6 does do VBZ cord-006870-f5w6fw6q 2073 7 not not RB cord-006870-f5w6fw6q 2073 8 worsen worsen VB cord-006870-f5w6fw6q 2073 9 stroke stroke NN cord-006870-f5w6fw6q 2073 10 symptoms symptom NNS cord-006870-f5w6fw6q 2073 11 or or CC cord-006870-f5w6fw6q 2073 12 severity severity NN cord-006870-f5w6fw6q 2073 13 based base VBN cord-006870-f5w6fw6q 2073 14 on on IN cord-006870-f5w6fw6q 2073 15 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2073 16 . . . cord-006870-f5w6fw6q 2074 1 This this DT cord-006870-f5w6fw6q 2074 2 suggests suggest VBZ cord-006870-f5w6fw6q 2074 3 that that IN cord-006870-f5w6fw6q 2074 4 very very RB cord-006870-f5w6fw6q 2074 5 early early JJ cord-006870-f5w6fw6q 2074 6 mobility mobility NN cord-006870-f5w6fw6q 2074 7 of of IN cord-006870-f5w6fw6q 2074 8 patients patient NNS cord-006870-f5w6fw6q 2074 9 after after IN cord-006870-f5w6fw6q 2074 10 IV IV NNP cord-006870-f5w6fw6q 2074 11 - - HYPH cord-006870-f5w6fw6q 2074 12 tPA tPA NNP cord-006870-f5w6fw6q 2074 13 is be VBZ cord-006870-f5w6fw6q 2074 14 safe safe JJ cord-006870-f5w6fw6q 2074 15 as as IN cord-006870-f5w6fw6q 2074 16 recommended recommend VBN cord-006870-f5w6fw6q 2074 17 by by IN cord-006870-f5w6fw6q 2074 18 ASA ASA NNP cord-006870-f5w6fw6q 2074 19 . . . cord-006870-f5w6fw6q 2075 1 Interhospital Interhospital NNP cord-006870-f5w6fw6q 2075 2 transfers transfer VBZ cord-006870-f5w6fw6q 2075 3 to to IN cord-006870-f5w6fw6q 2075 4 a a DT cord-006870-f5w6fw6q 2075 5 Stroke Stroke NNP cord-006870-f5w6fw6q 2075 6 Center Center NNP cord-006870-f5w6fw6q 2075 7 following follow VBG cord-006870-f5w6fw6q 2075 8 IV IV NNP cord-006870-f5w6fw6q 2075 9 - - HYPH cord-006870-f5w6fw6q 2075 10 tPA tPA NNP cord-006870-f5w6fw6q 2075 11 administration administration NN cord-006870-f5w6fw6q 2075 12 are be VBP cord-006870-f5w6fw6q 2075 13 increasingly increasingly RB cord-006870-f5w6fw6q 2075 14 common common JJ cord-006870-f5w6fw6q 2075 15 . . . cord-006870-f5w6fw6q 2076 1 However however RB cord-006870-f5w6fw6q 2076 2 , , , cord-006870-f5w6fw6q 2076 3 no no DT cord-006870-f5w6fw6q 2076 4 studies study NNS cord-006870-f5w6fw6q 2076 5 have have VBP cord-006870-f5w6fw6q 2076 6 evaluated evaluate VBN cord-006870-f5w6fw6q 2076 7 ICU ICU NNP cord-006870-f5w6fw6q 2076 8 needs need NNS cord-006870-f5w6fw6q 2076 9 in in IN cord-006870-f5w6fw6q 2076 10 these these DT cord-006870-f5w6fw6q 2076 11 transfer transfer NN cord-006870-f5w6fw6q 2076 12 patients patient NNS cord-006870-f5w6fw6q 2076 13 and and CC cord-006870-f5w6fw6q 2076 14 such such JJ cord-006870-f5w6fw6q 2076 15 understanding understanding NN cord-006870-f5w6fw6q 2076 16 may may MD cord-006870-f5w6fw6q 2076 17 have have VB cord-006870-f5w6fw6q 2076 18 a a DT cord-006870-f5w6fw6q 2076 19 significant significant JJ cord-006870-f5w6fw6q 2076 20 impact impact NN cord-006870-f5w6fw6q 2076 21 on on IN cord-006870-f5w6fw6q 2076 22 resource resource NN cord-006870-f5w6fw6q 2076 23 utilization utilization NN cord-006870-f5w6fw6q 2076 24 . . . cord-006870-f5w6fw6q 2077 1 The the DT cord-006870-f5w6fw6q 2077 2 aim aim NN cord-006870-f5w6fw6q 2077 3 of of IN cord-006870-f5w6fw6q 2077 4 this this DT cord-006870-f5w6fw6q 2077 5 study study NN cord-006870-f5w6fw6q 2077 6 is be VBZ cord-006870-f5w6fw6q 2077 7 to to TO cord-006870-f5w6fw6q 2077 8 compare compare VB cord-006870-f5w6fw6q 2077 9 the the DT cord-006870-f5w6fw6q 2077 10 frequency frequency NN cord-006870-f5w6fw6q 2077 11 , , , cord-006870-f5w6fw6q 2077 12 timing timing NN cord-006870-f5w6fw6q 2077 13 , , , cord-006870-f5w6fw6q 2077 14 and and CC cord-006870-f5w6fw6q 2077 15 nature nature NN cord-006870-f5w6fw6q 2077 16 of of IN cord-006870-f5w6fw6q 2077 17 ICU ICU NNP cord-006870-f5w6fw6q 2077 18 - - HYPH cord-006870-f5w6fw6q 2077 19 level level NN cord-006870-f5w6fw6q 2077 20 needs need NNS cord-006870-f5w6fw6q 2077 21 in in IN cord-006870-f5w6fw6q 2077 22 post post JJ cord-006870-f5w6fw6q 2077 23 - - JJ cord-006870-f5w6fw6q 2077 24 IV IV NNP cord-006870-f5w6fw6q 2077 25 - - HYPH cord-006870-f5w6fw6q 2077 26 tPA tPA NNP cord-006870-f5w6fw6q 2077 27 patients patient NNS cord-006870-f5w6fw6q 2077 28 that that WDT cord-006870-f5w6fw6q 2077 29 were be VBD cord-006870-f5w6fw6q 2077 30 transferred transfer VBN cord-006870-f5w6fw6q 2077 31 versus versus IN cord-006870-f5w6fw6q 2077 32 those those DT cord-006870-f5w6fw6q 2077 33 who who WP cord-006870-f5w6fw6q 2077 34 present present VBP cord-006870-f5w6fw6q 2077 35 directly directly RB cord-006870-f5w6fw6q 2077 36 to to IN cord-006870-f5w6fw6q 2077 37 the the DT cord-006870-f5w6fw6q 2077 38 admitting admit VBG cord-006870-f5w6fw6q 2077 39 hospital hospital NN cord-006870-f5w6fw6q 2077 40 . . . cord-006870-f5w6fw6q 2078 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 2078 2 chart chart NN cord-006870-f5w6fw6q 2078 3 review review NN cord-006870-f5w6fw6q 2078 4 of of IN cord-006870-f5w6fw6q 2078 5 consecutive consecutive JJ cord-006870-f5w6fw6q 2078 6 , , , cord-006870-f5w6fw6q 2078 7 tPA tPA NNP cord-006870-f5w6fw6q 2078 8 - - HYPH cord-006870-f5w6fw6q 2078 9 treated treat VBN cord-006870-f5w6fw6q 2078 10 ischemic ischemic JJ cord-006870-f5w6fw6q 2078 11 stroke stroke NN cord-006870-f5w6fw6q 2078 12 patients patient NNS cord-006870-f5w6fw6q 2078 13 admitted admit VBD cord-006870-f5w6fw6q 2078 14 to to IN cord-006870-f5w6fw6q 2078 15 the the DT cord-006870-f5w6fw6q 2078 16 ICU ICU NNP cord-006870-f5w6fw6q 2078 17 at at IN cord-006870-f5w6fw6q 2078 18 a a DT cord-006870-f5w6fw6q 2078 19 Comprehensive Comprehensive NNP cord-006870-f5w6fw6q 2078 20 Stroke Stroke NNP cord-006870-f5w6fw6q 2078 21 Center Center NNP cord-006870-f5w6fw6q 2078 22 servicing service VBG cord-006870-f5w6fw6q 2078 23 a a DT cord-006870-f5w6fw6q 2078 24 large large JJ cord-006870-f5w6fw6q 2078 25 Telestroke Telestroke NNP cord-006870-f5w6fw6q 2078 26 referral referral NN cord-006870-f5w6fw6q 2078 27 network network NN cord-006870-f5w6fw6q 2078 28 from from IN cord-006870-f5w6fw6q 2078 29 11/2013 11/2013 CD cord-006870-f5w6fw6q 2078 30 to to IN cord-006870-f5w6fw6q 2078 31 7/2015 7/2015 NNP cord-006870-f5w6fw6q 2078 32 was be VBD cord-006870-f5w6fw6q 2078 33 performed perform VBN cord-006870-f5w6fw6q 2078 34 . . . cord-006870-f5w6fw6q 2079 1 We -PRON- PRP cord-006870-f5w6fw6q 2079 2 evaluated evaluate VBD cord-006870-f5w6fw6q 2079 3 patient patient JJ cord-006870-f5w6fw6q 2079 4 demographics demographic NNS cord-006870-f5w6fw6q 2079 5 , , , cord-006870-f5w6fw6q 2079 6 stroke stroke NN cord-006870-f5w6fw6q 2079 7 characteristics characteristic NNS cord-006870-f5w6fw6q 2079 8 , , , cord-006870-f5w6fw6q 2079 9 and and CC cord-006870-f5w6fw6q 2079 10 ICU ICU NNP cord-006870-f5w6fw6q 2079 11 needs need VBZ cord-006870-f5w6fw6q 2079 12 between between IN cord-006870-f5w6fw6q 2079 13 transfer transfer NN cord-006870-f5w6fw6q 2079 14 and and CC cord-006870-f5w6fw6q 2079 15 non non JJ cord-006870-f5w6fw6q 2079 16 - - JJ cord-006870-f5w6fw6q 2079 17 transfer transfer JJ cord-006870-f5w6fw6q 2079 18 patients patient NNS cord-006870-f5w6fw6q 2079 19 before before IN cord-006870-f5w6fw6q 2079 20 and and CC cord-006870-f5w6fw6q 2079 21 after after IN cord-006870-f5w6fw6q 2079 22 ICU ICU NNP cord-006870-f5w6fw6q 2079 23 admission admission NN cord-006870-f5w6fw6q 2079 24 . . . cord-006870-f5w6fw6q 2080 1 Results result NNS cord-006870-f5w6fw6q 2080 2 331 331 CD cord-006870-f5w6fw6q 2080 3 patients patient NNS cord-006870-f5w6fw6q 2080 4 were be VBD cord-006870-f5w6fw6q 2080 5 admitted admit VBN cord-006870-f5w6fw6q 2080 6 to to IN cord-006870-f5w6fw6q 2080 7 the the DT cord-006870-f5w6fw6q 2080 8 ICU ICU NNP cord-006870-f5w6fw6q 2080 9 post post NN cord-006870-f5w6fw6q 2080 10 - - NNP cord-006870-f5w6fw6q 2080 11 tPA tpa NN cord-006870-f5w6fw6q 2080 12 . . . cord-006870-f5w6fw6q 2080 13 237 237 CD cord-006870-f5w6fw6q 2080 14 patients patient NNS cord-006870-f5w6fw6q 2080 15 ( ( -LRB- cord-006870-f5w6fw6q 2080 16 71.6 71.6 CD cord-006870-f5w6fw6q 2080 17 % % NN cord-006870-f5w6fw6q 2080 18 ) ) -RRB- cord-006870-f5w6fw6q 2080 19 were be VBD cord-006870-f5w6fw6q 2080 20 transferred transfer VBN cord-006870-f5w6fw6q 2080 21 from from IN cord-006870-f5w6fw6q 2080 22 an an DT cord-006870-f5w6fw6q 2080 23 outside outside JJ cord-006870-f5w6fw6q 2080 24 hospital hospital NN cord-006870-f5w6fw6q 2080 25 , , , cord-006870-f5w6fw6q 2080 26 of of IN cord-006870-f5w6fw6q 2080 27 which which WDT cord-006870-f5w6fw6q 2080 28 123 123 CD cord-006870-f5w6fw6q 2080 29 patients patient NNS cord-006870-f5w6fw6q 2080 30 had have VBD cord-006870-f5w6fw6q 2080 31 ICU ICU NNP cord-006870-f5w6fw6q 2080 32 needs need NNS cord-006870-f5w6fw6q 2080 33 ( ( -LRB- cord-006870-f5w6fw6q 2080 34 51.9 51.9 CD cord-006870-f5w6fw6q 2080 35 % % NN cord-006870-f5w6fw6q 2080 36 ) ) -RRB- cord-006870-f5w6fw6q 2080 37 . . . cord-006870-f5w6fw6q 2081 1 This this DT cord-006870-f5w6fw6q 2081 2 frequency frequency NN cord-006870-f5w6fw6q 2081 3 of of IN cord-006870-f5w6fw6q 2081 4 ICU ICU NNP cord-006870-f5w6fw6q 2081 5 needs need NNS cord-006870-f5w6fw6q 2081 6 was be VBD cord-006870-f5w6fw6q 2081 7 no no RB cord-006870-f5w6fw6q 2081 8 different different JJ cord-006870-f5w6fw6q 2081 9 when when WRB cord-006870-f5w6fw6q 2081 10 compared compare VBN cord-006870-f5w6fw6q 2081 11 to to IN cord-006870-f5w6fw6q 2081 12 the the DT cord-006870-f5w6fw6q 2081 13 non non JJ cord-006870-f5w6fw6q 2081 14 - - JJ cord-006870-f5w6fw6q 2081 15 transfer transfer JJ cord-006870-f5w6fw6q 2081 16 patients patient NNS cord-006870-f5w6fw6q 2081 17 ( ( -LRB- cord-006870-f5w6fw6q 2081 18 47/94 47/94 CD cord-006870-f5w6fw6q 2081 19 , , , cord-006870-f5w6fw6q 2081 20 50.0 50.0 CD cord-006870-f5w6fw6q 2081 21 % % NN cord-006870-f5w6fw6q 2081 22 , , , cord-006870-f5w6fw6q 2081 23 p p NN cord-006870-f5w6fw6q 2081 24 = = SYM cord-006870-f5w6fw6q 2081 25 0.81 0.81 CD cord-006870-f5w6fw6q 2081 26 ) ) -RRB- cord-006870-f5w6fw6q 2081 27 . . . cord-006870-f5w6fw6q 2082 1 Similar similar JJ cord-006870-f5w6fw6q 2082 2 ICU ICU NNP cord-006870-f5w6fw6q 2082 3 needs need NNS cord-006870-f5w6fw6q 2082 4 were be VBD cord-006870-f5w6fw6q 2082 5 observed observe VBN cord-006870-f5w6fw6q 2082 6 for for IN cord-006870-f5w6fw6q 2082 7 each each DT cord-006870-f5w6fw6q 2082 8 specific specific JJ cord-006870-f5w6fw6q 2082 9 ICU ICU NNP cord-006870-f5w6fw6q 2082 10 intervention intervention NN cord-006870-f5w6fw6q 2082 11 between between IN cord-006870-f5w6fw6q 2082 12 transfer transfer NN cord-006870-f5w6fw6q 2082 13 and and CC cord-006870-f5w6fw6q 2082 14 non non JJ cord-006870-f5w6fw6q 2082 15 - - JJ cord-006870-f5w6fw6q 2082 16 transfer transfer JJ cord-006870-f5w6fw6q 2082 17 patients patient NNS cord-006870-f5w6fw6q 2082 18 ( ( -LRB- cord-006870-f5w6fw6q 2082 19 IV IV NNP cord-006870-f5w6fw6q 2082 20 antihypertensive antihypertensive NN cord-006870-f5w6fw6q 2082 21 , , , cord-006870-f5w6fw6q 2082 22 vasopressor vasopressor NN cord-006870-f5w6fw6q 2082 23 requirement requirement NN cord-006870-f5w6fw6q 2082 24 , , , cord-006870-f5w6fw6q 2082 25 IV IV NNP cord-006870-f5w6fw6q 2082 26 rate rate NN cord-006870-f5w6fw6q 2082 27 control control NN cord-006870-f5w6fw6q 2082 28 , , , cord-006870-f5w6fw6q 2082 29 respiratory respiratory JJ cord-006870-f5w6fw6q 2082 30 support support NN cord-006870-f5w6fw6q 2082 31 , , , cord-006870-f5w6fw6q 2082 32 IA IA NNP cord-006870-f5w6fw6q 2082 33 therapy therapy NN cord-006870-f5w6fw6q 2082 34 , , , cord-006870-f5w6fw6q 2082 35 ICP ICP NNP cord-006870-f5w6fw6q 2082 36 monitoring monitoring NN cord-006870-f5w6fw6q 2082 37 , , , cord-006870-f5w6fw6q 2082 38 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2082 39 therapy therapy NN cord-006870-f5w6fw6q 2082 40 , , , cord-006870-f5w6fw6q 2082 41 and and CC cord-006870-f5w6fw6q 2082 42 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 2082 43 intervention intervention NN cord-006870-f5w6fw6q 2082 44 , , , cord-006870-f5w6fw6q 2082 45 all all DT cord-006870-f5w6fw6q 2082 46 p p NN cord-006870-f5w6fw6q 2082 47 > > XX cord-006870-f5w6fw6q 2082 48 0 0 CD cord-006870-f5w6fw6q 2082 49 association association NN cord-006870-f5w6fw6q 2082 50 with with IN cord-006870-f5w6fw6q 2082 51 ICU ICU NNP cord-006870-f5w6fw6q 2082 52 needs need NNS cord-006870-f5w6fw6q 2082 53 ( ( -LRB- cord-006870-f5w6fw6q 2082 54 OR or CC cord-006870-f5w6fw6q 2082 55 11.9 11.9 CD cord-006870-f5w6fw6q 2082 56 in in IN cord-006870-f5w6fw6q 2082 57 transfer transfer NN cord-006870-f5w6fw6q 2082 58 patients patient NNS cord-006870-f5w6fw6q 2082 59 , , , cord-006870-f5w6fw6q 2082 60 OR or CC cord-006870-f5w6fw6q 2082 61 9.7 9.7 CD cord-006870-f5w6fw6q 2082 62 in in IN cord-006870-f5w6fw6q 2082 63 non non JJ cord-006870-f5w6fw6q 2082 64 - - JJ cord-006870-f5w6fw6q 2082 65 transfer transfer JJ cord-006870-f5w6fw6q 2082 66 ; ; : cord-006870-f5w6fw6q 2082 67 both both DT cord-006870-f5w6fw6q 2082 68 p p XX cord-006870-f5w6fw6q 2082 69 < < XX cord-006870-f5w6fw6q 2082 70 0.0001 0.0001 CD cord-006870-f5w6fw6q 2082 71 ) ) -RRB- cord-006870-f5w6fw6q 2082 72 . . . cord-006870-f5w6fw6q 2083 1 Transferring transfer VBG cord-006870-f5w6fw6q 2083 2 post post JJ cord-006870-f5w6fw6q 2083 3 - - JJ cord-006870-f5w6fw6q 2083 4 IV IV NNP cord-006870-f5w6fw6q 2083 5 - - HYPH cord-006870-f5w6fw6q 2083 6 tPA tPA NNP cord-006870-f5w6fw6q 2083 7 patients patient NNS cord-006870-f5w6fw6q 2083 8 is be VBZ cord-006870-f5w6fw6q 2083 9 not not RB cord-006870-f5w6fw6q 2083 10 associated associate VBN cord-006870-f5w6fw6q 2083 11 with with IN cord-006870-f5w6fw6q 2083 12 increased increase VBN cord-006870-f5w6fw6q 2083 13 ICU ICU NNP cord-006870-f5w6fw6q 2083 14 needs need NNS cord-006870-f5w6fw6q 2083 15 . . . cord-006870-f5w6fw6q 2084 1 About about RB cord-006870-f5w6fw6q 2084 2 one one CD cord-006870-f5w6fw6q 2084 3 - - HYPH cord-006870-f5w6fw6q 2084 4 half half NN cord-006870-f5w6fw6q 2084 5 of of IN cord-006870-f5w6fw6q 2084 6 post post JJ cord-006870-f5w6fw6q 2084 7 - - JJ cord-006870-f5w6fw6q 2084 8 tPA tpa JJ cord-006870-f5w6fw6q 2084 9 patients patient NNS cord-006870-f5w6fw6q 2084 10 do do VBP cord-006870-f5w6fw6q 2084 11 not not RB cord-006870-f5w6fw6q 2084 12 have have VB cord-006870-f5w6fw6q 2084 13 ICU ICU NNP cord-006870-f5w6fw6q 2084 14 needs need NNS cord-006870-f5w6fw6q 2084 15 , , , cord-006870-f5w6fw6q 2084 16 and and CC cord-006870-f5w6fw6q 2084 17 these these DT cord-006870-f5w6fw6q 2084 18 patients patient NNS cord-006870-f5w6fw6q 2084 19 typically typically RB cord-006870-f5w6fw6q 2084 20 have have VBP cord-006870-f5w6fw6q 2084 21 milder mild JJR cord-006870-f5w6fw6q 2084 22 stroke stroke NN cord-006870-f5w6fw6q 2084 23 severity severity NN cord-006870-f5w6fw6q 2084 24 . . . cord-006870-f5w6fw6q 2085 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2085 2 data data NN cord-006870-f5w6fw6q 2085 3 supports support VBZ cord-006870-f5w6fw6q 2085 4 the the DT cord-006870-f5w6fw6q 2085 5 safety safety NN cord-006870-f5w6fw6q 2085 6 of of IN cord-006870-f5w6fw6q 2085 7 transferring transfer VBG cord-006870-f5w6fw6q 2085 8 post post JJ cord-006870-f5w6fw6q 2085 9 - - JJ cord-006870-f5w6fw6q 2085 10 tPA tpa JJ cord-006870-f5w6fw6q 2085 11 patients patient NNS cord-006870-f5w6fw6q 2085 12 , , , cord-006870-f5w6fw6q 2085 13 and and CC cord-006870-f5w6fw6q 2085 14 to to TO cord-006870-f5w6fw6q 2085 15 potentially potentially RB cord-006870-f5w6fw6q 2085 16 monitor monitor VB cord-006870-f5w6fw6q 2085 17 a a DT cord-006870-f5w6fw6q 2085 18 subgroup subgroup NN cord-006870-f5w6fw6q 2085 19 of of IN cord-006870-f5w6fw6q 2085 20 these these DT cord-006870-f5w6fw6q 2085 21 patients patient NNS cord-006870-f5w6fw6q 2085 22 in in IN cord-006870-f5w6fw6q 2085 23 a a DT cord-006870-f5w6fw6q 2085 24 non non JJ cord-006870-f5w6fw6q 2085 25 - - JJ cord-006870-f5w6fw6q 2085 26 ICU icu JJ cord-006870-f5w6fw6q 2085 27 setting setting NN cord-006870-f5w6fw6q 2085 28 . . . cord-006870-f5w6fw6q 2086 1 The the DT cord-006870-f5w6fw6q 2086 2 ability ability NN cord-006870-f5w6fw6q 2086 3 to to TO cord-006870-f5w6fw6q 2086 4 appropriately appropriately RB cord-006870-f5w6fw6q 2086 5 triage triage VB cord-006870-f5w6fw6q 2086 6 post post NN cord-006870-f5w6fw6q 2086 7 - - JJ cord-006870-f5w6fw6q 2086 8 tPA tpa JJ cord-006870-f5w6fw6q 2086 9 patients patient NNS cord-006870-f5w6fw6q 2086 10 may may MD cord-006870-f5w6fw6q 2086 11 lead lead VB cord-006870-f5w6fw6q 2086 12 to to IN cord-006870-f5w6fw6q 2086 13 more more RBR cord-006870-f5w6fw6q 2086 14 efficient efficient JJ cord-006870-f5w6fw6q 2086 15 and and CC cord-006870-f5w6fw6q 2086 16 cost cost NN cord-006870-f5w6fw6q 2086 17 - - HYPH cord-006870-f5w6fw6q 2086 18 effective effective JJ cord-006870-f5w6fw6q 2086 19 stroke stroke NN cord-006870-f5w6fw6q 2086 20 care care NN cord-006870-f5w6fw6q 2086 21 . . . cord-006870-f5w6fw6q 2087 1 Stroke stroke NN cord-006870-f5w6fw6q 2087 2 patients patient NNS cord-006870-f5w6fw6q 2087 3 requiring require VBG cord-006870-f5w6fw6q 2087 4 decompressive decompressive JJ cord-006870-f5w6fw6q 2087 5 craniectomy craniectomy NNP cord-006870-f5w6fw6q 2087 6 remain remain VBP cord-006870-f5w6fw6q 2087 7 at at IN cord-006870-f5w6fw6q 2087 8 high high JJ cord-006870-f5w6fw6q 2087 9 risk risk NN cord-006870-f5w6fw6q 2087 10 of of IN cord-006870-f5w6fw6q 2087 11 prolonged prolong VBN cord-006870-f5w6fw6q 2087 12 mechanical mechanical JJ cord-006870-f5w6fw6q 2087 13 ventilation ventilation NN cord-006870-f5w6fw6q 2087 14 as as RB cord-006870-f5w6fw6q 2087 15 well well RB cord-006870-f5w6fw6q 2087 16 as as IN cord-006870-f5w6fw6q 2087 17 ventilator ventilator NN cord-006870-f5w6fw6q 2087 18 associated associate VBD cord-006870-f5w6fw6q 2087 19 pneumonia pneumonia NN cord-006870-f5w6fw6q 2087 20 ( ( -LRB- cord-006870-f5w6fw6q 2087 21 VAP VAP NNP cord-006870-f5w6fw6q 2087 22 ) ) -RRB- cord-006870-f5w6fw6q 2087 23 . . . cord-006870-f5w6fw6q 2088 1 Early early JJ cord-006870-f5w6fw6q 2088 2 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2088 3 placement placement NN cord-006870-f5w6fw6q 2088 4 may may MD cord-006870-f5w6fw6q 2088 5 provide provide VB cord-006870-f5w6fw6q 2088 6 a a DT cord-006870-f5w6fw6q 2088 7 reduction reduction NN cord-006870-f5w6fw6q 2088 8 in in IN cord-006870-f5w6fw6q 2088 9 the the DT cord-006870-f5w6fw6q 2088 10 duration duration NN cord-006870-f5w6fw6q 2088 11 of of IN cord-006870-f5w6fw6q 2088 12 mechanical mechanical JJ cord-006870-f5w6fw6q 2088 13 ventilation ventilation NN cord-006870-f5w6fw6q 2088 14 however however RB cord-006870-f5w6fw6q 2088 15 prediction prediction NN cord-006870-f5w6fw6q 2088 16 of of IN cord-006870-f5w6fw6q 2088 17 those those DT cord-006870-f5w6fw6q 2088 18 who who WP cord-006870-f5w6fw6q 2088 19 ultimately ultimately RB cord-006870-f5w6fw6q 2088 20 require require VBP cord-006870-f5w6fw6q 2088 21 a a DT cord-006870-f5w6fw6q 2088 22 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2088 23 remains remain VBZ cord-006870-f5w6fw6q 2088 24 a a DT cord-006870-f5w6fw6q 2088 25 clinical clinical JJ cord-006870-f5w6fw6q 2088 26 challenge challenge NN cord-006870-f5w6fw6q 2088 27 . . . cord-006870-f5w6fw6q 2089 1 A a DT cord-006870-f5w6fw6q 2089 2 preoperative preoperative JJ cord-006870-f5w6fw6q 2089 3 assessment assessment NN cord-006870-f5w6fw6q 2089 4 of of IN cord-006870-f5w6fw6q 2089 5 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2089 6 dependence dependence NN cord-006870-f5w6fw6q 2089 7 may may MD cord-006870-f5w6fw6q 2089 8 help help VB cord-006870-f5w6fw6q 2089 9 to to TO cord-006870-f5w6fw6q 2089 10 guide guide VB cord-006870-f5w6fw6q 2089 11 decision decision NN cord-006870-f5w6fw6q 2089 12 making making NN cord-006870-f5w6fw6q 2089 13 . . . cord-006870-f5w6fw6q 2090 1 The the DT cord-006870-f5w6fw6q 2090 2 authors author NNS cord-006870-f5w6fw6q 2090 3 compare compare VBP cord-006870-f5w6fw6q 2090 4 key key JJ cord-006870-f5w6fw6q 2090 5 outcome outcome NN cord-006870-f5w6fw6q 2090 6 data datum NNS cord-006870-f5w6fw6q 2090 7 after after IN cord-006870-f5w6fw6q 2090 8 early early RB cord-006870-f5w6fw6q 2090 9 versus versus IN cord-006870-f5w6fw6q 2090 10 late late JJ cord-006870-f5w6fw6q 2090 11 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2090 12 and and CC cord-006870-f5w6fw6q 2090 13 develop develop VB cord-006870-f5w6fw6q 2090 14 a a DT cord-006870-f5w6fw6q 2090 15 preoperative preoperative JJ cord-006870-f5w6fw6q 2090 16 decision decision NN cord-006870-f5w6fw6q 2090 17 - - HYPH cord-006870-f5w6fw6q 2090 18 making make VBG cord-006870-f5w6fw6q 2090 19 tool tool NN cord-006870-f5w6fw6q 2090 20 to to TO cord-006870-f5w6fw6q 2090 21 predict predict VB cord-006870-f5w6fw6q 2090 22 postoperative postoperative JJ cord-006870-f5w6fw6q 2090 23 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2090 24 dependence dependence NN cord-006870-f5w6fw6q 2090 25 . . . cord-006870-f5w6fw6q 2091 1 A a DT cord-006870-f5w6fw6q 2091 2 subsequent subsequent JJ cord-006870-f5w6fw6q 2091 3 validation validation NN cord-006870-f5w6fw6q 2091 4 utilizing utilize VBG cord-006870-f5w6fw6q 2091 5 a a DT cord-006870-f5w6fw6q 2091 6 decision decision NN cord-006870-f5w6fw6q 2091 7 tree tree NN cord-006870-f5w6fw6q 2091 8 analysis analysis NN cord-006870-f5w6fw6q 2091 9 applied apply VBN cord-006870-f5w6fw6q 2091 10 prospectively prospectively RB cord-006870-f5w6fw6q 2091 11 is be VBZ cord-006870-f5w6fw6q 2091 12 ongoing ongoing JJ cord-006870-f5w6fw6q 2091 13 and and CC cord-006870-f5w6fw6q 2091 14 will will MD cord-006870-f5w6fw6q 2091 15 be be VB cord-006870-f5w6fw6q 2091 16 presented present VBN cord-006870-f5w6fw6q 2091 17 . . . cord-006870-f5w6fw6q 2092 1 We -PRON- PRP cord-006870-f5w6fw6q 2092 2 performed perform VBD cord-006870-f5w6fw6q 2092 3 a a DT cord-006870-f5w6fw6q 2092 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2092 5 analysis analysis NN cord-006870-f5w6fw6q 2092 6 of of IN cord-006870-f5w6fw6q 2092 7 prospectively prospectively RB cord-006870-f5w6fw6q 2092 8 collected collect VBN cord-006870-f5w6fw6q 2092 9 registry registry NN cord-006870-f5w6fw6q 2092 10 data datum NNS cord-006870-f5w6fw6q 2092 11 and and CC cord-006870-f5w6fw6q 2092 12 developed develop VBD cord-006870-f5w6fw6q 2092 13 a a DT cord-006870-f5w6fw6q 2092 14 propensity propensity NN cord-006870-f5w6fw6q 2092 15 weighted weight VBN cord-006870-f5w6fw6q 2092 16 decision decision NN cord-006870-f5w6fw6q 2092 17 tree tree NN cord-006870-f5w6fw6q 2092 18 analysis analysis NN cord-006870-f5w6fw6q 2092 19 to to TO cord-006870-f5w6fw6q 2092 20 predict predict VB cord-006870-f5w6fw6q 2092 21 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2092 22 requirement requirement NN cord-006870-f5w6fw6q 2092 23 utilizing utilize VBG cord-006870-f5w6fw6q 2092 24 factors factor NNS cord-006870-f5w6fw6q 2092 25 present present VBP cord-006870-f5w6fw6q 2092 26 prior prior RB cord-006870-f5w6fw6q 2092 27 to to IN cord-006870-f5w6fw6q 2092 28 surgical surgical JJ cord-006870-f5w6fw6q 2092 29 decompression decompression NN cord-006870-f5w6fw6q 2092 30 . . . cord-006870-f5w6fw6q 2093 1 Outcomes outcome NNS cord-006870-f5w6fw6q 2093 2 include include VBP cord-006870-f5w6fw6q 2093 3 probability probability NN cord-006870-f5w6fw6q 2093 4 functions function NNS cord-006870-f5w6fw6q 2093 5 for for IN cord-006870-f5w6fw6q 2093 6 ICU ICU NNP cord-006870-f5w6fw6q 2093 7 LOS LOS NNP cord-006870-f5w6fw6q 2093 8 , , , cord-006870-f5w6fw6q 2093 9 Hospital Hospital NNP cord-006870-f5w6fw6q 2093 10 LOS LOS NNP cord-006870-f5w6fw6q 2093 11 , , , cord-006870-f5w6fw6q 2093 12 and and CC cord-006870-f5w6fw6q 2093 13 mortality mortality NN cord-006870-f5w6fw6q 2093 14 based base VBN cord-006870-f5w6fw6q 2093 15 on on IN cord-006870-f5w6fw6q 2093 16 data datum NNS cord-006870-f5w6fw6q 2093 17 for for IN cord-006870-f5w6fw6q 2093 18 early early JJ cord-006870-f5w6fw6q 2093 19 ( ( -LRB- cord-006870-f5w6fw6q 2093 20 10 10 CD cord-006870-f5w6fw6q 2093 21 day day NN cord-006870-f5w6fw6q 2093 22 ) ) -RRB- cord-006870-f5w6fw6q 2093 23 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2093 24 . . . cord-006870-f5w6fw6q 2094 1 A a DT cord-006870-f5w6fw6q 2094 2 subsequent subsequent JJ cord-006870-f5w6fw6q 2094 3 validation validation NN cord-006870-f5w6fw6q 2094 4 of of IN cord-006870-f5w6fw6q 2094 5 the the DT cord-006870-f5w6fw6q 2094 6 decision decision NN cord-006870-f5w6fw6q 2094 7 tree tree NN cord-006870-f5w6fw6q 2094 8 is be VBZ cord-006870-f5w6fw6q 2094 9 being be VBG cord-006870-f5w6fw6q 2094 10 applied apply VBN cord-006870-f5w6fw6q 2094 11 prospectively prospectively RB cord-006870-f5w6fw6q 2094 12 to to TO cord-006870-f5w6fw6q 2094 13 evaluate evaluate VB cord-006870-f5w6fw6q 2094 14 its -PRON- PRP$ cord-006870-f5w6fw6q 2094 15 predictive predictive JJ cord-006870-f5w6fw6q 2094 16 value value NN cord-006870-f5w6fw6q 2094 17 . . . cord-006870-f5w6fw6q 2095 1 A a DT cord-006870-f5w6fw6q 2095 2 total total NN cord-006870-f5w6fw6q 2095 3 of of IN cord-006870-f5w6fw6q 2095 4 168 168 CD cord-006870-f5w6fw6q 2095 5 surgical surgical JJ cord-006870-f5w6fw6q 2095 6 decompressions decompression NNS cord-006870-f5w6fw6q 2095 7 were be VBD cord-006870-f5w6fw6q 2095 8 performed perform VBN cord-006870-f5w6fw6q 2095 9 on on IN cord-006870-f5w6fw6q 2095 10 patients patient NNS cord-006870-f5w6fw6q 2095 11 with with IN cord-006870-f5w6fw6q 2095 12 acute acute JJ cord-006870-f5w6fw6q 2095 13 ischemic ischemic JJ cord-006870-f5w6fw6q 2095 14 or or CC cord-006870-f5w6fw6q 2095 15 spontaneous spontaneous JJ cord-006870-f5w6fw6q 2095 16 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 2095 17 stroke stroke NN cord-006870-f5w6fw6q 2095 18 between between IN cord-006870-f5w6fw6q 2095 19 2010 2010 CD cord-006870-f5w6fw6q 2095 20 - - SYM cord-006870-f5w6fw6q 2095 21 2015 2015 CD cord-006870-f5w6fw6q 2095 22 . . . cord-006870-f5w6fw6q 2096 1 Forty forty CD cord-006870-f5w6fw6q 2096 2 eight eight CD cord-006870-f5w6fw6q 2096 3 patients patient NNS cord-006870-f5w6fw6q 2096 4 ( ( -LRB- cord-006870-f5w6fw6q 2096 5 28.5 28.5 CD cord-006870-f5w6fw6q 2096 6 % % NN cord-006870-f5w6fw6q 2096 7 ) ) -RRB- cord-006870-f5w6fw6q 2096 8 required require VBD cord-006870-f5w6fw6q 2096 9 a a DT cord-006870-f5w6fw6q 2096 10 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2096 11 , , , cord-006870-f5w6fw6q 2096 12 whereas whereas IN cord-006870-f5w6fw6q 2096 13 35 35 CD cord-006870-f5w6fw6q 2096 14 ( ( -LRB- cord-006870-f5w6fw6q 2096 15 20.8 20.8 CD cord-006870-f5w6fw6q 2096 16 % % NN cord-006870-f5w6fw6q 2096 17 ) ) -RRB- cord-006870-f5w6fw6q 2096 18 developed develop VBD cord-006870-f5w6fw6q 2096 19 VAP VAP NNP cord-006870-f5w6fw6q 2096 20 , , , cord-006870-f5w6fw6q 2096 21 and and CC cord-006870-f5w6fw6q 2096 22 126 126 CD cord-006870-f5w6fw6q 2096 23 ( ( -LRB- cord-006870-f5w6fw6q 2096 24 75 75 CD cord-006870-f5w6fw6q 2096 25 % % NN cord-006870-f5w6fw6q 2096 26 ) ) -RRB- cord-006870-f5w6fw6q 2096 27 survived survive VBD cord-006870-f5w6fw6q 2096 28 hospitalization hospitalization NN cord-006870-f5w6fw6q 2096 29 . . . cord-006870-f5w6fw6q 2097 1 Mean mean JJ cord-006870-f5w6fw6q 2097 2 ICU ICU NNP cord-006870-f5w6fw6q 2097 3 and and CC cord-006870-f5w6fw6q 2097 4 hospital hospital NN cord-006870-f5w6fw6q 2097 5 LOS LOS NNP cord-006870-f5w6fw6q 2097 6 were be VBD cord-006870-f5w6fw6q 2097 7 15.1 15.1 CD cord-006870-f5w6fw6q 2097 8 and and CC cord-006870-f5w6fw6q 2097 9 25.8 25.8 CD cord-006870-f5w6fw6q 2097 10 days day NNS cord-006870-f5w6fw6q 2097 11 respectively respectively RB cord-006870-f5w6fw6q 2097 12 . . . cord-006870-f5w6fw6q 2098 1 Utilizing utilize VBG cord-006870-f5w6fw6q 2098 2 GCS GCS NNP cord-006870-f5w6fw6q 2098 3 , , , cord-006870-f5w6fw6q 2098 4 SOFA sofa NN cord-006870-f5w6fw6q 2098 5 score score NN cord-006870-f5w6fw6q 2098 6 and and CC cord-006870-f5w6fw6q 2098 7 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 2098 8 presence presence NN cord-006870-f5w6fw6q 2098 9 , , , cord-006870-f5w6fw6q 2098 10 our -PRON- PRP$ cord-006870-f5w6fw6q 2098 11 decision decision NN cord-006870-f5w6fw6q 2098 12 tree tree NN cord-006870-f5w6fw6q 2098 13 analysis analysis NN cord-006870-f5w6fw6q 2098 14 provided provide VBD cord-006870-f5w6fw6q 2098 15 a a DT cord-006870-f5w6fw6q 2098 16 63 63 CD cord-006870-f5w6fw6q 2098 17 % % NN cord-006870-f5w6fw6q 2098 18 sensitivity sensitivity NN cord-006870-f5w6fw6q 2098 19 and and CC cord-006870-f5w6fw6q 2098 20 84 84 CD cord-006870-f5w6fw6q 2098 21 % % NN cord-006870-f5w6fw6q 2098 22 specificity specificity NN cord-006870-f5w6fw6q 2098 23 for for IN cord-006870-f5w6fw6q 2098 24 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2098 25 prediction prediction NN cord-006870-f5w6fw6q 2098 26 . . . cord-006870-f5w6fw6q 2099 1 Early early JJ cord-006870-f5w6fw6q 2099 2 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2099 3 conferred confer VBD cord-006870-f5w6fw6q 2099 4 significantly significantly RB cord-006870-f5w6fw6q 2099 5 fewer few JJR cord-006870-f5w6fw6q 2099 6 ventilator ventilator NN cord-006870-f5w6fw6q 2099 7 days day NNS cord-006870-f5w6fw6q 2099 8 ( ( -LRB- cord-006870-f5w6fw6q 2099 9 p<0.001 p<0.001 JJ cord-006870-f5w6fw6q 2099 10 ) ) -RRB- cord-006870-f5w6fw6q 2099 11 and and CC cord-006870-f5w6fw6q 2099 12 shorter short JJR cord-006870-f5w6fw6q 2099 13 hospital hospital NN cord-006870-f5w6fw6q 2099 14 LOS LOS NNP cord-006870-f5w6fw6q 2099 15 ( ( -LRB- cord-006870-f5w6fw6q 2099 16 p=0.014 p=0.014 NNS cord-006870-f5w6fw6q 2099 17 ) ) -RRB- cord-006870-f5w6fw6q 2099 18 with with IN cord-006870-f5w6fw6q 2099 19 similar similar JJ cord-006870-f5w6fw6q 2099 20 VAP VAP NNP cord-006870-f5w6fw6q 2099 21 and and CC cord-006870-f5w6fw6q 2099 22 mortality mortality NN cord-006870-f5w6fw6q 2099 23 rates rate NNS cord-006870-f5w6fw6q 2099 24 between between IN cord-006870-f5w6fw6q 2099 25 groups group NNS cord-006870-f5w6fw6q 2099 26 . . . cord-006870-f5w6fw6q 2100 1 Early early JJ cord-006870-f5w6fw6q 2100 2 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2100 3 shortens shorten VBZ cord-006870-f5w6fw6q 2100 4 duration duration NN cord-006870-f5w6fw6q 2100 5 of of IN cord-006870-f5w6fw6q 2100 6 mechanical mechanical JJ cord-006870-f5w6fw6q 2100 7 ventilation ventilation NN cord-006870-f5w6fw6q 2100 8 and and CC cord-006870-f5w6fw6q 2100 9 length length NN cord-006870-f5w6fw6q 2100 10 of of IN cord-006870-f5w6fw6q 2100 11 stay stay NN cord-006870-f5w6fw6q 2100 12 following follow VBG cord-006870-f5w6fw6q 2100 13 surgical surgical JJ cord-006870-f5w6fw6q 2100 14 decompression decompression NN cord-006870-f5w6fw6q 2100 15 for for IN cord-006870-f5w6fw6q 2100 16 stroke stroke NN cord-006870-f5w6fw6q 2100 17 , , , cord-006870-f5w6fw6q 2100 18 however however RB cord-006870-f5w6fw6q 2100 19 without without IN cord-006870-f5w6fw6q 2100 20 a a DT cord-006870-f5w6fw6q 2100 21 demonstrable demonstrable JJ cord-006870-f5w6fw6q 2100 22 impact impact NN cord-006870-f5w6fw6q 2100 23 in in IN cord-006870-f5w6fw6q 2100 24 mortality mortality NN cord-006870-f5w6fw6q 2100 25 or or CC cord-006870-f5w6fw6q 2100 26 VAP VAP NNP cord-006870-f5w6fw6q 2100 27 rates rate NNS cord-006870-f5w6fw6q 2100 28 . . . cord-006870-f5w6fw6q 2101 1 A a DT cord-006870-f5w6fw6q 2101 2 preoperative preoperative JJ cord-006870-f5w6fw6q 2101 3 decision decision NN cord-006870-f5w6fw6q 2101 4 tree tree NN cord-006870-f5w6fw6q 2101 5 awards award VBZ cord-006870-f5w6fw6q 2101 6 a a DT cord-006870-f5w6fw6q 2101 7 practical practical JJ cord-006870-f5w6fw6q 2101 8 tool tool NN cord-006870-f5w6fw6q 2101 9 that that WDT cord-006870-f5w6fw6q 2101 10 may may MD cord-006870-f5w6fw6q 2101 11 provide provide VB cord-006870-f5w6fw6q 2101 12 insight insight NN cord-006870-f5w6fw6q 2101 13 to to TO cord-006870-f5w6fw6q 2101 14 guide guide VB cord-006870-f5w6fw6q 2101 15 preoperative preoperative JJ cord-006870-f5w6fw6q 2101 16 decision decision NN cord-006870-f5w6fw6q 2101 17 - - HYPH cord-006870-f5w6fw6q 2101 18 making making NN cord-006870-f5w6fw6q 2101 19 with with IN cord-006870-f5w6fw6q 2101 20 patient patient JJ cord-006870-f5w6fw6q 2101 21 families family NNS cord-006870-f5w6fw6q 2101 22 . . . cord-006870-f5w6fw6q 2102 1 Patients patient NNS cord-006870-f5w6fw6q 2102 2 suspected suspect VBD cord-006870-f5w6fw6q 2102 3 acute acute JJ cord-006870-f5w6fw6q 2102 4 stroke stroke NN cord-006870-f5w6fw6q 2102 5 are be VBP cord-006870-f5w6fw6q 2102 6 critical critical JJ cord-006870-f5w6fw6q 2102 7 in in IN cord-006870-f5w6fw6q 2102 8 time time NN cord-006870-f5w6fw6q 2102 9 delay delay NN cord-006870-f5w6fw6q 2102 10 of of IN cord-006870-f5w6fw6q 2102 11 endovascular endovascular JJ cord-006870-f5w6fw6q 2102 12 or or CC cord-006870-f5w6fw6q 2102 13 intravenous intravenous JJ cord-006870-f5w6fw6q 2102 14 thrombolytic thrombolytic NN cord-006870-f5w6fw6q 2102 15 therapy therapy NN cord-006870-f5w6fw6q 2102 16 . . . cord-006870-f5w6fw6q 2103 1 Prehospital prehospital JJ cord-006870-f5w6fw6q 2103 2 notification notification NN cord-006870-f5w6fw6q 2103 3 from from IN cord-006870-f5w6fw6q 2103 4 emergency emergency NN cord-006870-f5w6fw6q 2103 5 medical medical JJ cord-006870-f5w6fw6q 2103 6 services service NNS cord-006870-f5w6fw6q 2103 7 ( ( -LRB- cord-006870-f5w6fw6q 2103 8 EMS EMS NNP cord-006870-f5w6fw6q 2103 9 ) ) -RRB- cord-006870-f5w6fw6q 2103 10 may may MD cord-006870-f5w6fw6q 2103 11 shorten shorten VB cord-006870-f5w6fw6q 2103 12 the the DT cord-006870-f5w6fw6q 2103 13 door door NN cord-006870-f5w6fw6q 2103 14 to to TO cord-006870-f5w6fw6q 2103 15 recanalization recanalization VB cord-006870-f5w6fw6q 2103 16 time time NN cord-006870-f5w6fw6q 2103 17 . . . cord-006870-f5w6fw6q 2104 1 The the DT cord-006870-f5w6fw6q 2104 2 ' ' `` cord-006870-f5w6fw6q 2104 3 Brain Brain NNP cord-006870-f5w6fw6q 2104 4 Saver Saver NNP cord-006870-f5w6fw6q 2104 5 ' ' '' cord-006870-f5w6fw6q 2104 6 , , , cord-006870-f5w6fw6q 2104 7 web web NN cord-006870-f5w6fw6q 2104 8 - - HYPH cord-006870-f5w6fw6q 2104 9 based base VBN cord-006870-f5w6fw6q 2104 10 prehospital prehospital JJ cord-006870-f5w6fw6q 2104 11 notification notification NN cord-006870-f5w6fw6q 2104 12 system system NN cord-006870-f5w6fw6q 2104 13 could could MD cord-006870-f5w6fw6q 2104 14 reduce reduce VB cord-006870-f5w6fw6q 2104 15 the the DT cord-006870-f5w6fw6q 2104 16 time time NN cord-006870-f5w6fw6q 2104 17 interval interval NN cord-006870-f5w6fw6q 2104 18 from from IN cord-006870-f5w6fw6q 2104 19 symptom symptom NN cord-006870-f5w6fw6q 2104 20 onset onset NN cord-006870-f5w6fw6q 2104 21 to to IN cord-006870-f5w6fw6q 2104 22 recanalization recanalization NN cord-006870-f5w6fw6q 2104 23 . . . cord-006870-f5w6fw6q 2105 1 Beginning begin VBG cord-006870-f5w6fw6q 2105 2 in in IN cord-006870-f5w6fw6q 2105 3 March March NNP cord-006870-f5w6fw6q 2105 4 2016 2016 CD cord-006870-f5w6fw6q 2105 5 , , , cord-006870-f5w6fw6q 2105 6 stroke stroke NN cord-006870-f5w6fw6q 2105 7 team team NN cord-006870-f5w6fw6q 2105 8 consisted consist VBD cord-006870-f5w6fw6q 2105 9 of of IN cord-006870-f5w6fw6q 2105 10 stroke stroke NN cord-006870-f5w6fw6q 2105 11 specialized specialized JJ cord-006870-f5w6fw6q 2105 12 doctors doctor NNS cord-006870-f5w6fw6q 2105 13 , , , cord-006870-f5w6fw6q 2105 14 nurses nurse NNS cord-006870-f5w6fw6q 2105 15 and and CC cord-006870-f5w6fw6q 2105 16 radiologists radiologist NNS cord-006870-f5w6fw6q 2105 17 of of IN cord-006870-f5w6fw6q 2105 18 multi multi JJ cord-006870-f5w6fw6q 2105 19 departments department NNS cord-006870-f5w6fw6q 2105 20 received receive VBD cord-006870-f5w6fw6q 2105 21 direct direct JJ cord-006870-f5w6fw6q 2105 22 alarms alarm NNS cord-006870-f5w6fw6q 2105 23 via via IN cord-006870-f5w6fw6q 2105 24 smart smart JJ cord-006870-f5w6fw6q 2105 25 phone phone NN cord-006870-f5w6fw6q 2105 26 application application NN cord-006870-f5w6fw6q 2105 27 from from IN cord-006870-f5w6fw6q 2105 28 paramedics paramedic NNS cord-006870-f5w6fw6q 2105 29 of of IN cord-006870-f5w6fw6q 2105 30 EMS EMS NNP cord-006870-f5w6fw6q 2105 31 about about IN cord-006870-f5w6fw6q 2105 32 transport transport NN cord-006870-f5w6fw6q 2105 33 information information NN cord-006870-f5w6fw6q 2105 34 of of IN cord-006870-f5w6fw6q 2105 35 patients patient NNS cord-006870-f5w6fw6q 2105 36 with with IN cord-006870-f5w6fw6q 2105 37 suspected suspect VBN cord-006870-f5w6fw6q 2105 38 stroke stroke NN cord-006870-f5w6fw6q 2105 39 . . . cord-006870-f5w6fw6q 2106 1 We -PRON- PRP cord-006870-f5w6fw6q 2106 2 compared compare VBD cord-006870-f5w6fw6q 2106 3 baseline baseline JJ cord-006870-f5w6fw6q 2106 4 characteristics characteristic NNS cord-006870-f5w6fw6q 2106 5 and and CC cord-006870-f5w6fw6q 2106 6 prehospital/ prehospital/ CD cord-006870-f5w6fw6q 2106 7 in in IN cord-006870-f5w6fw6q 2106 8 - - HYPH cord-006870-f5w6fw6q 2106 9 hospital hospital NN cord-006870-f5w6fw6q 2106 10 delay delay NN cord-006870-f5w6fw6q 2106 11 time time NN cord-006870-f5w6fw6q 2106 12 in in IN cord-006870-f5w6fw6q 2106 13 stroke stroke NN cord-006870-f5w6fw6q 2106 14 patients patient NNS cord-006870-f5w6fw6q 2106 15 treated treat VBN cord-006870-f5w6fw6q 2106 16 with with IN cord-006870-f5w6fw6q 2106 17 intravenous intravenous JJ cord-006870-f5w6fw6q 2106 18 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 2106 19 or or CC cord-006870-f5w6fw6q 2106 20 endovascular endovascular JJ cord-006870-f5w6fw6q 2106 21 treatment treatment NN cord-006870-f5w6fw6q 2106 22 for for IN cord-006870-f5w6fw6q 2106 23 12 12 CD cord-006870-f5w6fw6q 2106 24 months month NNS cord-006870-f5w6fw6q 2106 25 with with IN cord-006870-f5w6fw6q 2106 26 and and CC cord-006870-f5w6fw6q 2106 27 without without IN cord-006870-f5w6fw6q 2106 28 EMS EMS NNP cord-006870-f5w6fw6q 2106 29 use use VBP cord-006870-f5w6fw6q 2106 30 Brain Brain NNP cord-006870-f5w6fw6q 2106 31 Saver Saver NNP cord-006870-f5w6fw6q 2106 32 Protocol Protocol NNP cord-006870-f5w6fw6q 2106 33 . . . cord-006870-f5w6fw6q 2107 1 167 167 CD cord-006870-f5w6fw6q 2107 2 patients patient NNS cord-006870-f5w6fw6q 2107 3 ( ( -LRB- cord-006870-f5w6fw6q 2107 4 69 69 CD cord-006870-f5w6fw6q 2107 5 patients patient NNS cord-006870-f5w6fw6q 2107 6 with with IN cord-006870-f5w6fw6q 2107 7 protocol protocol NN cord-006870-f5w6fw6q 2107 8 and and CC cord-006870-f5w6fw6q 2107 9 98 98 CD cord-006870-f5w6fw6q 2107 10 patients patient NNS cord-006870-f5w6fw6q 2107 11 without without IN cord-006870-f5w6fw6q 2107 12 protocol protocol NN cord-006870-f5w6fw6q 2107 13 ) ) -RRB- cord-006870-f5w6fw6q 2107 14 were be VBD cord-006870-f5w6fw6q 2107 15 enrolled enrol VBN cord-006870-f5w6fw6q 2107 16 in in IN cord-006870-f5w6fw6q 2107 17 this this DT cord-006870-f5w6fw6q 2107 18 program program NN cord-006870-f5w6fw6q 2107 19 . . . cord-006870-f5w6fw6q 2108 1 The the DT cord-006870-f5w6fw6q 2108 2 patients patient NNS cord-006870-f5w6fw6q 2108 3 who who WP cord-006870-f5w6fw6q 2108 4 used use VBD cord-006870-f5w6fw6q 2108 5 Brain Brain NNP cord-006870-f5w6fw6q 2108 6 Saver Saver NNP cord-006870-f5w6fw6q 2108 7 had have VBD cord-006870-f5w6fw6q 2108 8 shorter short JJR cord-006870-f5w6fw6q 2108 9 median median JJ cord-006870-f5w6fw6q 2108 10 onset onset NN cord-006870-f5w6fw6q 2108 11 - - HYPH cord-006870-f5w6fw6q 2108 12 to to IN cord-006870-f5w6fw6q 2108 13 - - HYPH cord-006870-f5w6fw6q 2108 14 arrival arrival NN cord-006870-f5w6fw6q 2108 15 times time NNS cord-006870-f5w6fw6q 2108 16 ( ( -LRB- cord-006870-f5w6fw6q 2108 17 63 63 CD cord-006870-f5w6fw6q 2108 18 minutes minute NNS cord-006870-f5w6fw6q 2108 19 versus versus IN cord-006870-f5w6fw6q 2108 20 142 142 CD cord-006870-f5w6fw6q 2108 21 minutes minute NNS cord-006870-f5w6fw6q 2108 22 , , , cord-006870-f5w6fw6q 2108 23 P p NN cord-006870-f5w6fw6q 2108 24 < < XX cord-006870-f5w6fw6q 2108 25 .001 .001 CD cord-006870-f5w6fw6q 2108 26 ) ) -RRB- cord-006870-f5w6fw6q 2108 27 and and CC cord-006870-f5w6fw6q 2108 28 in in IN cord-006870-f5w6fw6q 2108 29 in in IN cord-006870-f5w6fw6q 2108 30 - - HYPH cord-006870-f5w6fw6q 2108 31 hospital hospital NN cord-006870-f5w6fw6q 2108 32 delay delay NN cord-006870-f5w6fw6q 2108 33 time time NN cord-006870-f5w6fw6q 2108 34 ( ( -LRB- cord-006870-f5w6fw6q 2108 35 35 35 CD cord-006870-f5w6fw6q 2108 36 minutes minute NNS cord-006870-f5w6fw6q 2108 37 versus versus IN cord-006870-f5w6fw6q 2108 38 52 52 CD cord-006870-f5w6fw6q 2108 39 minutes minute NNS cord-006870-f5w6fw6q 2108 40 , , , cord-006870-f5w6fw6q 2108 41 P<.001 P<.001 NNP cord-006870-f5w6fw6q 2108 42 ) ) -RRB- cord-006870-f5w6fw6q 2108 43 . . . cord-006870-f5w6fw6q 2109 1 Prehospital prehospital JJ cord-006870-f5w6fw6q 2109 2 notification notification NN cord-006870-f5w6fw6q 2109 3 by by IN cord-006870-f5w6fw6q 2109 4 Brain Brain NNP cord-006870-f5w6fw6q 2109 5 Saver Saver NNP cord-006870-f5w6fw6q 2109 6 was be VBD cord-006870-f5w6fw6q 2109 7 associated associate VBN cord-006870-f5w6fw6q 2109 8 with with IN cord-006870-f5w6fw6q 2109 9 shorter short JJR cord-006870-f5w6fw6q 2109 10 median median JJ cord-006870-f5w6fw6q 2109 11 door door NN cord-006870-f5w6fw6q 2109 12 - - HYPH cord-006870-f5w6fw6q 2109 13 to to IN cord-006870-f5w6fw6q 2109 14 - - HYPH cord-006870-f5w6fw6q 2109 15 imaging imaging NN cord-006870-f5w6fw6q 2109 16 time time NN cord-006870-f5w6fw6q 2109 17 ( ( -LRB- cord-006870-f5w6fw6q 2109 18 5 5 CD cord-006870-f5w6fw6q 2109 19 minutes minute NNS cord-006870-f5w6fw6q 2109 20 versus versus IN cord-006870-f5w6fw6q 2109 21 12 12 CD cord-006870-f5w6fw6q 2109 22 minutes minute NNS cord-006870-f5w6fw6q 2109 23 , , , cord-006870-f5w6fw6q 2109 24 P<.001 P<.001 NNP cord-006870-f5w6fw6q 2109 25 ) ) -RRB- cord-006870-f5w6fw6q 2109 26 , , , cord-006870-f5w6fw6q 2109 27 door door NN cord-006870-f5w6fw6q 2109 28 - - HYPH cord-006870-f5w6fw6q 2109 29 to to IN cord-006870-f5w6fw6q 2109 30 - - HYPH cord-006870-f5w6fw6q 2109 31 needle needle NN cord-006870-f5w6fw6q 2109 32 time time NN cord-006870-f5w6fw6q 2109 33 ( ( -LRB- cord-006870-f5w6fw6q 2109 34 20 20 CD cord-006870-f5w6fw6q 2109 35 minutes minute NNS cord-006870-f5w6fw6q 2109 36 versus versus IN cord-006870-f5w6fw6q 2109 37 31 31 CD cord-006870-f5w6fw6q 2109 38 minutes minute NNS cord-006870-f5w6fw6q 2109 39 , , , cord-006870-f5w6fw6q 2109 40 P p NN cord-006870-f5w6fw6q 2109 41 < < XX cord-006870-f5w6fw6q 2109 42 .05 .05 NFP cord-006870-f5w6fw6q 2109 43 ) ) -RRB- cord-006870-f5w6fw6q 2109 44 , , , cord-006870-f5w6fw6q 2109 45 door door NN cord-006870-f5w6fw6q 2109 46 to to TO cord-006870-f5w6fw6q 2109 47 puncture puncture VB cord-006870-f5w6fw6q 2109 48 time time NN cord-006870-f5w6fw6q 2109 49 ( ( -LRB- cord-006870-f5w6fw6q 2109 50 55 55 CD cord-006870-f5w6fw6q 2109 51 minutes minute NNS cord-006870-f5w6fw6q 2109 52 versus versus IN cord-006870-f5w6fw6q 2109 53 137 137 CD cord-006870-f5w6fw6q 2109 54 minutes minute NNS cord-006870-f5w6fw6q 2109 55 , , , cord-006870-f5w6fw6q 2109 56 P p NN cord-006870-f5w6fw6q 2109 57 < < XX cord-006870-f5w6fw6q 2109 58 .001 .001 CD cord-006870-f5w6fw6q 2109 59 ) ) -RRB- cord-006870-f5w6fw6q 2110 1 We -PRON- PRP cord-006870-f5w6fw6q 2110 2 found find VBD cord-006870-f5w6fw6q 2110 3 that that IN cord-006870-f5w6fw6q 2110 4 prehospital prehospital JJ cord-006870-f5w6fw6q 2110 5 notification notification NN cord-006870-f5w6fw6q 2110 6 was be VBD cord-006870-f5w6fw6q 2110 7 associated associate VBN cord-006870-f5w6fw6q 2110 8 with with IN cord-006870-f5w6fw6q 2110 9 faster fast JJR cord-006870-f5w6fw6q 2110 10 door door NN cord-006870-f5w6fw6q 2110 11 - - HYPH cord-006870-f5w6fw6q 2110 12 to to IN cord-006870-f5w6fw6q 2110 13 - - HYPH cord-006870-f5w6fw6q 2110 14 imaging imaging NN cord-006870-f5w6fw6q 2110 15 time time NN cord-006870-f5w6fw6q 2110 16 , , , cord-006870-f5w6fw6q 2110 17 door door NN cord-006870-f5w6fw6q 2110 18 - - HYPH cord-006870-f5w6fw6q 2110 19 to to IN cord-006870-f5w6fw6q 2110 20 - - HYPH cord-006870-f5w6fw6q 2110 21 needle needle NN cord-006870-f5w6fw6q 2110 22 time time NN cord-006870-f5w6fw6q 2110 23 and and CC cord-006870-f5w6fw6q 2110 24 door door NN cord-006870-f5w6fw6q 2110 25 - - HYPH cord-006870-f5w6fw6q 2110 26 to to IN cord-006870-f5w6fw6q 2110 27 - - HYPH cord-006870-f5w6fw6q 2110 28 puncture puncture NN cord-006870-f5w6fw6q 2110 29 time time NN cord-006870-f5w6fw6q 2110 30 in in IN cord-006870-f5w6fw6q 2110 31 patients patient NNS cord-006870-f5w6fw6q 2110 32 presenting present VBG cord-006870-f5w6fw6q 2110 33 within within IN cord-006870-f5w6fw6q 2110 34 6 6 CD cord-006870-f5w6fw6q 2110 35 hours hour NNS cord-006870-f5w6fw6q 2110 36 of of IN cord-006870-f5w6fw6q 2110 37 symptom symptom NN cord-006870-f5w6fw6q 2110 38 onset onset NN cord-006870-f5w6fw6q 2110 39 . . . cord-006870-f5w6fw6q 2111 1 Close close JJ cord-006870-f5w6fw6q 2111 2 collaboration collaboration NN cord-006870-f5w6fw6q 2111 3 between between IN cord-006870-f5w6fw6q 2111 4 stroke stroke NN cord-006870-f5w6fw6q 2111 5 team team NN cord-006870-f5w6fw6q 2111 6 in in IN cord-006870-f5w6fw6q 2111 7 hospitals hospital NNS cord-006870-f5w6fw6q 2111 8 and and CC cord-006870-f5w6fw6q 2111 9 the the DT cord-006870-f5w6fw6q 2111 10 EMS EMS NNP cord-006870-f5w6fw6q 2111 11 system system NN cord-006870-f5w6fw6q 2111 12 gives give VBZ cord-006870-f5w6fw6q 2111 13 stroke stroke NN cord-006870-f5w6fw6q 2111 14 suspected suspect VBN cord-006870-f5w6fw6q 2111 15 patients patient NNS cord-006870-f5w6fw6q 2111 16 an an DT cord-006870-f5w6fw6q 2111 17 in in IN cord-006870-f5w6fw6q 2111 18 - - HYPH cord-006870-f5w6fw6q 2111 19 time time NN cord-006870-f5w6fw6q 2111 20 emergency emergency NN cord-006870-f5w6fw6q 2111 21 care care NN cord-006870-f5w6fw6q 2111 22 system system NN cord-006870-f5w6fw6q 2111 23 . . . cord-006870-f5w6fw6q 2112 1 Infection infection NN cord-006870-f5w6fw6q 2112 2 is be VBZ cord-006870-f5w6fw6q 2112 3 a a DT cord-006870-f5w6fw6q 2112 4 common common JJ cord-006870-f5w6fw6q 2112 5 complication complication NN cord-006870-f5w6fw6q 2112 6 in in IN cord-006870-f5w6fw6q 2112 7 the the DT cord-006870-f5w6fw6q 2112 8 acute acute JJ cord-006870-f5w6fw6q 2112 9 phase phase NN cord-006870-f5w6fw6q 2112 10 after after IN cord-006870-f5w6fw6q 2112 11 ischemic ischemic JJ cord-006870-f5w6fw6q 2112 12 stroke stroke NN cord-006870-f5w6fw6q 2112 13 . . . cord-006870-f5w6fw6q 2113 1 Furthermore furthermore RB cord-006870-f5w6fw6q 2113 2 , , , cord-006870-f5w6fw6q 2113 3 malnutrition malnutrition NN cord-006870-f5w6fw6q 2113 4 is be VBZ cord-006870-f5w6fw6q 2113 5 associated associate VBN cord-006870-f5w6fw6q 2113 6 with with IN cord-006870-f5w6fw6q 2113 7 unfavorable unfavorable JJ cord-006870-f5w6fw6q 2113 8 outcome outcome NN cord-006870-f5w6fw6q 2113 9 in in IN cord-006870-f5w6fw6q 2113 10 patients patient NNS cord-006870-f5w6fw6q 2113 11 with with IN cord-006870-f5w6fw6q 2113 12 stroke stroke NN cord-006870-f5w6fw6q 2113 13 . . . cord-006870-f5w6fw6q 2114 1 Therefore therefore RB cord-006870-f5w6fw6q 2114 2 , , , cord-006870-f5w6fw6q 2114 3 we -PRON- PRP cord-006870-f5w6fw6q 2114 4 investigated investigate VBD cord-006870-f5w6fw6q 2114 5 that that IN cord-006870-f5w6fw6q 2114 6 premorbid premorbid NN cord-006870-f5w6fw6q 2114 7 undernutrition undernutrition NN cord-006870-f5w6fw6q 2114 8 identified identify VBN cord-006870-f5w6fw6q 2114 9 by by IN cord-006870-f5w6fw6q 2114 10 objective objective JJ cord-006870-f5w6fw6q 2114 11 and and CC cord-006870-f5w6fw6q 2114 12 quantitative quantitative JJ cord-006870-f5w6fw6q 2114 13 method method NN cord-006870-f5w6fw6q 2114 14 , , , cord-006870-f5w6fw6q 2114 15 Nutritional Nutritional NNP cord-006870-f5w6fw6q 2114 16 Risk Risk NNP cord-006870-f5w6fw6q 2114 17 Index Index NNP cord-006870-f5w6fw6q 2114 18 ( ( -LRB- cord-006870-f5w6fw6q 2114 19 NRI NRI NNP cord-006870-f5w6fw6q 2114 20 ) ) -RRB- cord-006870-f5w6fw6q 2114 21 was be VBD cord-006870-f5w6fw6q 2114 22 related relate VBN cord-006870-f5w6fw6q 2114 23 to to IN cord-006870-f5w6fw6q 2114 24 the the DT cord-006870-f5w6fw6q 2114 25 risk risk NN cord-006870-f5w6fw6q 2114 26 of of IN cord-006870-f5w6fw6q 2114 27 infection infection NN cord-006870-f5w6fw6q 2114 28 after after IN cord-006870-f5w6fw6q 2114 29 ischemic ischemic JJ cord-006870-f5w6fw6q 2114 30 stroke stroke NN cord-006870-f5w6fw6q 2114 31 . . . cord-006870-f5w6fw6q 2115 1 A a DT cord-006870-f5w6fw6q 2115 2 consecutive consecutive JJ cord-006870-f5w6fw6q 2115 3 852 852 CD cord-006870-f5w6fw6q 2115 4 patients patient NNS cord-006870-f5w6fw6q 2115 5 who who WP cord-006870-f5w6fw6q 2115 6 were be VBD cord-006870-f5w6fw6q 2115 7 admitted admit VBN cord-006870-f5w6fw6q 2115 8 within within IN cord-006870-f5w6fw6q 2115 9 7 7 CD cord-006870-f5w6fw6q 2115 10 days day NNS cord-006870-f5w6fw6q 2115 11 after after IN cord-006870-f5w6fw6q 2115 12 ischemic ischemic JJ cord-006870-f5w6fw6q 2115 13 stroke stroke NN cord-006870-f5w6fw6q 2115 14 onset onset NN cord-006870-f5w6fw6q 2115 15 between between IN cord-006870-f5w6fw6q 2115 16 October October NNP cord-006870-f5w6fw6q 2115 17 2010 2010 CD cord-006870-f5w6fw6q 2115 18 and and CC cord-006870-f5w6fw6q 2115 19 October October NNP cord-006870-f5w6fw6q 2115 20 2015 2015 CD cord-006870-f5w6fw6q 2115 21 were be VBD cord-006870-f5w6fw6q 2115 22 included include VBN cord-006870-f5w6fw6q 2115 23 . . . cord-006870-f5w6fw6q 2116 1 We -PRON- PRP cord-006870-f5w6fw6q 2116 2 assessed assess VBD cord-006870-f5w6fw6q 2116 3 initial initial JJ cord-006870-f5w6fw6q 2116 4 nutritional nutritional JJ cord-006870-f5w6fw6q 2116 5 status status NN cord-006870-f5w6fw6q 2116 6 using use VBG cord-006870-f5w6fw6q 2116 7 NRI NRI NNP cord-006870-f5w6fw6q 2116 8 , , , cord-006870-f5w6fw6q 2116 9 and and CC cord-006870-f5w6fw6q 2116 10 NRI NRI NNP cord-006870-f5w6fw6q 2116 11 formula formula NN cord-006870-f5w6fw6q 2116 12 as as IN cord-006870-f5w6fw6q 2116 13 follows follow VBZ cord-006870-f5w6fw6q 2116 14 : : : cord-006870-f5w6fw6q 2116 15 NRI NRI NNP cord-006870-f5w6fw6q 2116 16 = = NFP cord-006870-f5w6fw6q 2117 1 ( ( -LRB- cord-006870-f5w6fw6q 2117 2 1.519 1.519 CD cord-006870-f5w6fw6q 2117 3 × × NN cord-006870-f5w6fw6q 2117 4 serum serum NN cord-006870-f5w6fw6q 2117 5 albumin albumin NN cord-006870-f5w6fw6q 2117 6 , , , cord-006870-f5w6fw6q 2117 7 g g NN cord-006870-f5w6fw6q 2117 8 / / SYM cord-006870-f5w6fw6q 2117 9 dL dl NN cord-006870-f5w6fw6q 2117 10 ) ) -RRB- cord-006870-f5w6fw6q 2117 11 + + CC cord-006870-f5w6fw6q 2117 12 { { -LRB- cord-006870-f5w6fw6q 2117 13 41.7 41.7 CD cord-006870-f5w6fw6q 2117 14 × × NN cord-006870-f5w6fw6q 2117 15 present present JJ cord-006870-f5w6fw6q 2117 16 weight weight NN cord-006870-f5w6fw6q 2117 17 ( ( -LRB- cord-006870-f5w6fw6q 2117 18 kg)/ideal kg)/ideal DT cord-006870-f5w6fw6q 2117 19 body body NN cord-006870-f5w6fw6q 2117 20 weight weight NN cord-006870-f5w6fw6q 2117 21 ( ( -LRB- cord-006870-f5w6fw6q 2117 22 kg kg NNP cord-006870-f5w6fw6q 2117 23 ) ) -RRB- cord-006870-f5w6fw6q 2117 24 } } -RRB- cord-006870-f5w6fw6q 2117 25 . . . cord-006870-f5w6fw6q 2118 1 The the DT cord-006870-f5w6fw6q 2118 2 patients patient NNS cord-006870-f5w6fw6q 2118 3 were be VBD cord-006870-f5w6fw6q 2118 4 categorized categorize VBN cord-006870-f5w6fw6q 2118 5 into into IN cord-006870-f5w6fw6q 2118 6 three three CD cord-006870-f5w6fw6q 2118 7 groups group NNS cord-006870-f5w6fw6q 2118 8 on on IN cord-006870-f5w6fw6q 2118 9 the the DT cord-006870-f5w6fw6q 2118 10 basis basis NN cord-006870-f5w6fw6q 2118 11 of of IN cord-006870-f5w6fw6q 2118 12 NRI NRI NNP cord-006870-f5w6fw6q 2119 1 [ [ -LRB- cord-006870-f5w6fw6q 2119 2 No no DT cord-006870-f5w6fw6q 2119 3 risk risk NN cord-006870-f5w6fw6q 2119 4 ( ( -LRB- cord-006870-f5w6fw6q 2119 5 NRI NRI NNP cord-006870-f5w6fw6q 2119 6 > > XX cord-006870-f5w6fw6q 2119 7 97.5 97.5 CD cord-006870-f5w6fw6q 2119 8 ) ) -RRB- cord-006870-f5w6fw6q 2119 9 , , , cord-006870-f5w6fw6q 2119 10 Moderate moderate JJ cord-006870-f5w6fw6q 2119 11 risk risk NN cord-006870-f5w6fw6q 2119 12 ( ( -LRB- cord-006870-f5w6fw6q 2119 13 NRI NRI NNP cord-006870-f5w6fw6q 2119 14 83.5 83.5 CD cord-006870-f5w6fw6q 2119 15 - - HYPH cord-006870-f5w6fw6q 2119 16 97.5 97.5 CD cord-006870-f5w6fw6q 2119 17 ) ) -RRB- cord-006870-f5w6fw6q 2119 18 , , , cord-006870-f5w6fw6q 2119 19 and and CC cord-006870-f5w6fw6q 2119 20 Severe severe JJ cord-006870-f5w6fw6q 2119 21 risk risk NN cord-006870-f5w6fw6q 2119 22 ( ( -LRB- cord-006870-f5w6fw6q 2119 23 NRI NRI NNP cord-006870-f5w6fw6q 2119 24 < < XX cord-006870-f5w6fw6q 2119 25 83.5 83.5 CD cord-006870-f5w6fw6q 2119 26 ) ) -RRB- cord-006870-f5w6fw6q 2119 27 ] ] -RRB- cord-006870-f5w6fw6q 2119 28 . . . cord-006870-f5w6fw6q 2120 1 We -PRON- PRP cord-006870-f5w6fw6q 2120 2 compared compare VBD cord-006870-f5w6fw6q 2120 3 the the DT cord-006870-f5w6fw6q 2120 4 clinical clinical JJ cord-006870-f5w6fw6q 2120 5 characteristics characteristic NNS cord-006870-f5w6fw6q 2120 6 and and CC cord-006870-f5w6fw6q 2120 7 NRI NRI NNP cord-006870-f5w6fw6q 2120 8 according accord VBG cord-006870-f5w6fw6q 2120 9 to to IN cord-006870-f5w6fw6q 2120 10 the the DT cord-006870-f5w6fw6q 2120 11 presence presence NN cord-006870-f5w6fw6q 2120 12 of of IN cord-006870-f5w6fw6q 2120 13 infection infection NN cord-006870-f5w6fw6q 2120 14 . . . cord-006870-f5w6fw6q 2121 1 Among among IN cord-006870-f5w6fw6q 2121 2 the the DT cord-006870-f5w6fw6q 2121 3 included include VBN cord-006870-f5w6fw6q 2121 4 patients patient NNS cord-006870-f5w6fw6q 2121 5 ( ( -LRB- cord-006870-f5w6fw6q 2121 6 mean mean VB cord-006870-f5w6fw6q 2121 7 age age NN cord-006870-f5w6fw6q 2121 8 , , , cord-006870-f5w6fw6q 2121 9 67.7 67.7 CD cord-006870-f5w6fw6q 2121 10 years year NNS cord-006870-f5w6fw6q 2121 11 , , , cord-006870-f5w6fw6q 2121 12 male male NN cord-006870-f5w6fw6q 2121 13 , , , cord-006870-f5w6fw6q 2121 14 60.6 60.6 CD cord-006870-f5w6fw6q 2121 15 % % NN cord-006870-f5w6fw6q 2121 16 ) ) -RRB- cord-006870-f5w6fw6q 2121 17 , , , cord-006870-f5w6fw6q 2121 18 85 85 CD cord-006870-f5w6fw6q 2121 19 ( ( -LRB- cord-006870-f5w6fw6q 2121 20 10.0 10.0 CD cord-006870-f5w6fw6q 2121 21 % % NN cord-006870-f5w6fw6q 2121 22 ) ) -RRB- cord-006870-f5w6fw6q 2121 23 patients patient NNS cord-006870-f5w6fw6q 2121 24 experienced experience VBD cord-006870-f5w6fw6q 2121 25 infection infection NN cord-006870-f5w6fw6q 2121 26 during during IN cord-006870-f5w6fw6q 2121 27 hospitalization hospitalization NN cord-006870-f5w6fw6q 2121 28 . . . cord-006870-f5w6fw6q 2122 1 The the DT cord-006870-f5w6fw6q 2122 2 rate rate NN cord-006870-f5w6fw6q 2122 3 of of IN cord-006870-f5w6fw6q 2122 4 pneumonia pneumonia NN cord-006870-f5w6fw6q 2122 5 was be VBD cord-006870-f5w6fw6q 2122 6 81.2 81.2 CD cord-006870-f5w6fw6q 2122 7 % % NN cord-006870-f5w6fw6q 2122 8 ( ( -LRB- cord-006870-f5w6fw6q 2122 9 n=69 n=69 NNP cord-006870-f5w6fw6q 2122 10 ) ) -RRB- cord-006870-f5w6fw6q 2122 11 , , , cord-006870-f5w6fw6q 2122 12 and and CC cord-006870-f5w6fw6q 2122 13 the the DT cord-006870-f5w6fw6q 2122 14 rate rate NN cord-006870-f5w6fw6q 2122 15 of of IN cord-006870-f5w6fw6q 2122 16 urinary urinary JJ cord-006870-f5w6fw6q 2122 17 tract tract NN cord-006870-f5w6fw6q 2122 18 infection infection NN cord-006870-f5w6fw6q 2122 19 was be VBD cord-006870-f5w6fw6q 2122 20 11.8 11.8 CD cord-006870-f5w6fw6q 2122 21 % % NN cord-006870-f5w6fw6q 2122 22 ( ( -LRB- cord-006870-f5w6fw6q 2122 23 n=10 n=10 NNP cord-006870-f5w6fw6q 2122 24 ) ) -RRB- cord-006870-f5w6fw6q 2122 25 among among IN cord-006870-f5w6fw6q 2122 26 total total JJ cord-006870-f5w6fw6q 2122 27 infection infection NN cord-006870-f5w6fw6q 2122 28 . . . cord-006870-f5w6fw6q 2123 1 The the DT cord-006870-f5w6fw6q 2123 2 proportion proportion NN cord-006870-f5w6fw6q 2123 3 of of IN cord-006870-f5w6fw6q 2123 4 lower low JJR cord-006870-f5w6fw6q 2123 5 NRI NRI NNP cord-006870-f5w6fw6q 2123 6 patients patient NNS cord-006870-f5w6fw6q 2123 7 ( ( -LRB- cord-006870-f5w6fw6q 2123 8 Moderate moderate JJ cord-006870-f5w6fw6q 2123 9 risk risk NN cord-006870-f5w6fw6q 2123 10 and and CC cord-006870-f5w6fw6q 2123 11 Severe severe JJ cord-006870-f5w6fw6q 2123 12 risk risk NN cord-006870-f5w6fw6q 2123 13 ) ) -RRB- cord-006870-f5w6fw6q 2123 14 was be VBD cord-006870-f5w6fw6q 2123 15 significantly significantly RB cord-006870-f5w6fw6q 2123 16 greater great JJR cord-006870-f5w6fw6q 2123 17 in in IN cord-006870-f5w6fw6q 2123 18 the the DT cord-006870-f5w6fw6q 2123 19 infection infection NN cord-006870-f5w6fw6q 2123 20 group group NN cord-006870-f5w6fw6q 2123 21 ( ( -LRB- cord-006870-f5w6fw6q 2123 22 45.9 45.9 CD cord-006870-f5w6fw6q 2123 23 % % NN cord-006870-f5w6fw6q 2123 24 vs. vs. CC cord-006870-f5w6fw6q 2123 25 17.9 17.9 CD cord-006870-f5w6fw6q 2123 26 % % NN cord-006870-f5w6fw6q 2123 27 and and CC cord-006870-f5w6fw6q 2123 28 10.6 10.6 CD cord-006870-f5w6fw6q 2123 29 % % NN cord-006870-f5w6fw6q 2123 30 vs. vs. CC cord-006870-f5w6fw6q 2123 31 2.7 2.7 CD cord-006870-f5w6fw6q 2123 32 % % NN cord-006870-f5w6fw6q 2123 33 , , , cord-006870-f5w6fw6q 2123 34 P p NN cord-006870-f5w6fw6q 2123 35 < < XX cord-006870-f5w6fw6q 2123 36 0.001 0.001 CD cord-006870-f5w6fw6q 2123 37 ) ) -RRB- cord-006870-f5w6fw6q 2123 38 . . . cord-006870-f5w6fw6q 2124 1 Moreover moreover RB cord-006870-f5w6fw6q 2124 2 , , , cord-006870-f5w6fw6q 2124 3 higher high JJR cord-006870-f5w6fw6q 2124 4 NRI NRI NNP cord-006870-f5w6fw6q 2124 5 patients patient NNS cord-006870-f5w6fw6q 2124 6 were be VBD cord-006870-f5w6fw6q 2124 7 less less RBR cord-006870-f5w6fw6q 2124 8 likely likely JJ cord-006870-f5w6fw6q 2124 9 to to TO cord-006870-f5w6fw6q 2124 10 be be VB cord-006870-f5w6fw6q 2124 11 admitted admit VBN cord-006870-f5w6fw6q 2124 12 to to IN cord-006870-f5w6fw6q 2124 13 the the DT cord-006870-f5w6fw6q 2124 14 intensive intensive JJ cord-006870-f5w6fw6q 2124 15 care care NN cord-006870-f5w6fw6q 2124 16 unit unit NN cord-006870-f5w6fw6q 2124 17 ( ( -LRB- cord-006870-f5w6fw6q 2124 18 1.4 1.4 CD cord-006870-f5w6fw6q 2124 19 % % NN cord-006870-f5w6fw6q 2124 20 vs. vs. IN cord-006870-f5w6fw6q 2124 21 5.1 5.1 CD cord-006870-f5w6fw6q 2124 22 % % NN cord-006870-f5w6fw6q 2124 23 vs. vs. CC cord-006870-f5w6fw6q 2124 24 6.7 6.7 CD cord-006870-f5w6fw6q 2124 25 % % NN cord-006870-f5w6fw6q 2124 26 , , , cord-006870-f5w6fw6q 2124 27 P p NN cord-006870-f5w6fw6q 2124 28 = = SYM cord-006870-f5w6fw6q 2124 29 0.004 0.004 CD cord-006870-f5w6fw6q 2124 30 ) ) -RRB- cord-006870-f5w6fw6q 2124 31 . . . cord-006870-f5w6fw6q 2125 1 A a DT cord-006870-f5w6fw6q 2125 2 multivariate multivariate JJ cord-006870-f5w6fw6q 2125 3 analysis analysis NN cord-006870-f5w6fw6q 2125 4 revealed reveal VBD cord-006870-f5w6fw6q 2125 5 that that IN cord-006870-f5w6fw6q 2125 6 lower low JJR cord-006870-f5w6fw6q 2125 7 NRI NRI NNP cord-006870-f5w6fw6q 2125 8 groups group NNS cord-006870-f5w6fw6q 2125 9 had have VBD cord-006870-f5w6fw6q 2125 10 a a DT cord-006870-f5w6fw6q 2125 11 higher high JJR cord-006870-f5w6fw6q 2125 12 risk risk NN cord-006870-f5w6fw6q 2125 13 of of IN cord-006870-f5w6fw6q 2125 14 infection infection NN cord-006870-f5w6fw6q 2125 15 [ [ -LRB- cord-006870-f5w6fw6q 2125 16 Odds odd NNS cord-006870-f5w6fw6q 2125 17 ratio ratio NN cord-006870-f5w6fw6q 2125 18 ( ( -LRB- cord-006870-f5w6fw6q 2125 19 95 95 CD cord-006870-f5w6fw6q 2125 20 % % NN cord-006870-f5w6fw6q 2125 21 confidence confidence NN cord-006870-f5w6fw6q 2125 22 interval interval NN cord-006870-f5w6fw6q 2125 23 ) ) -RRB- cord-006870-f5w6fw6q 2125 24 ; ; : cord-006870-f5w6fw6q 2125 25 Moderate moderate JJ cord-006870-f5w6fw6q 2125 26 risk risk NN cord-006870-f5w6fw6q 2125 27 3.98 3.98 CD cord-006870-f5w6fw6q 2125 28 ( ( -LRB- cord-006870-f5w6fw6q 2125 29 1.95 1.95 CD cord-006870-f5w6fw6q 2125 30 -8.13 -8.13 SYM cord-006870-f5w6fw6q 2125 31 ) ) -RRB- cord-006870-f5w6fw6q 2125 32 ; ; : cord-006870-f5w6fw6q 2125 33 Severe severe JJ cord-006870-f5w6fw6q 2125 34 risk risk NN cord-006870-f5w6fw6q 2125 35 4.21 4.21 CD cord-006870-f5w6fw6q 2125 36 ( ( -LRB- cord-006870-f5w6fw6q 2125 37 1.10 1.10 CD cord-006870-f5w6fw6q 2125 38 -16.14 -16.14 NNS cord-006870-f5w6fw6q 2125 39 ) ) -RRB- cord-006870-f5w6fw6q 2125 40 , , , cord-006870-f5w6fw6q 2125 41 P p NN cord-006870-f5w6fw6q 2125 42 for for IN cord-006870-f5w6fw6q 2125 43 trend trend NN cord-006870-f5w6fw6q 2125 44 = = SYM cord-006870-f5w6fw6q 2125 45 0.001 0.001 CD cord-006870-f5w6fw6q 2125 46 ] ] -RRB- cord-006870-f5w6fw6q 2125 47 . . . cord-006870-f5w6fw6q 2126 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2126 2 study study NN cord-006870-f5w6fw6q 2126 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 2126 4 that that IN cord-006870-f5w6fw6q 2126 5 the the DT cord-006870-f5w6fw6q 2126 6 lower low JJR cord-006870-f5w6fw6q 2126 7 NRIs nri NNS cord-006870-f5w6fw6q 2126 8 predicted predict VBD cord-006870-f5w6fw6q 2126 9 infection infection NN cord-006870-f5w6fw6q 2126 10 complications complication NNS cord-006870-f5w6fw6q 2126 11 and and CC cord-006870-f5w6fw6q 2126 12 severe severe JJ cord-006870-f5w6fw6q 2126 13 infections infection NNS cord-006870-f5w6fw6q 2126 14 after after IN cord-006870-f5w6fw6q 2126 15 ischemic ischemic JJ cord-006870-f5w6fw6q 2126 16 stroke stroke NN cord-006870-f5w6fw6q 2126 17 . . . cord-006870-f5w6fw6q 2127 1 This this DT cord-006870-f5w6fw6q 2127 2 suggests suggest VBZ cord-006870-f5w6fw6q 2127 3 that that DT cord-006870-f5w6fw6q 2127 4 assessment assessment NN cord-006870-f5w6fw6q 2127 5 of of IN cord-006870-f5w6fw6q 2127 6 nutrition nutrition NN cord-006870-f5w6fw6q 2127 7 depletion depletion NN cord-006870-f5w6fw6q 2127 8 could could MD cord-006870-f5w6fw6q 2127 9 be be VB cord-006870-f5w6fw6q 2127 10 a a DT cord-006870-f5w6fw6q 2127 11 useful useful JJ cord-006870-f5w6fw6q 2127 12 predictor predictor NN cord-006870-f5w6fw6q 2127 13 and and CC cord-006870-f5w6fw6q 2127 14 a a DT cord-006870-f5w6fw6q 2127 15 modifiable modifiable JJ cord-006870-f5w6fw6q 2127 16 risk risk NN cord-006870-f5w6fw6q 2127 17 factor factor NN cord-006870-f5w6fw6q 2127 18 for for IN cord-006870-f5w6fw6q 2127 19 infection infection NN cord-006870-f5w6fw6q 2127 20 following follow VBG cord-006870-f5w6fw6q 2127 21 stroke stroke NN cord-006870-f5w6fw6q 2127 22 . . . cord-006870-f5w6fw6q 2128 1 CYP2C19 CYP2C19 NNP cord-006870-f5w6fw6q 2128 2 plays play VBZ cord-006870-f5w6fw6q 2128 3 a a DT cord-006870-f5w6fw6q 2128 4 major major JJ cord-006870-f5w6fw6q 2128 5 role role NN cord-006870-f5w6fw6q 2128 6 in in IN cord-006870-f5w6fw6q 2128 7 the the DT cord-006870-f5w6fw6q 2128 8 metabolism metabolism NN cord-006870-f5w6fw6q 2128 9 of of IN cord-006870-f5w6fw6q 2128 10 the the DT cord-006870-f5w6fw6q 2128 11 clop[idogrel clop[idogrel NNS cord-006870-f5w6fw6q 2128 12 . . . cord-006870-f5w6fw6q 2129 1 CYP2C19 CYP2C19 NNP cord-006870-f5w6fw6q 2129 2 generates generate VBZ cord-006870-f5w6fw6q 2129 3 an an DT cord-006870-f5w6fw6q 2129 4 active active JJ cord-006870-f5w6fw6q 2129 5 oxidized oxidize VBN cord-006870-f5w6fw6q 2129 6 metabolite metabolite NN cord-006870-f5w6fw6q 2129 7 of of IN cord-006870-f5w6fw6q 2129 8 clopidogrel clopidogrel NN cord-006870-f5w6fw6q 2129 9 that that WDT cord-006870-f5w6fw6q 2129 10 exerts exert VBZ cord-006870-f5w6fw6q 2129 11 antipl;atelet antipl;atelet CD cord-006870-f5w6fw6q 2129 12 activity activity NN cord-006870-f5w6fw6q 2129 13 by by IN cord-006870-f5w6fw6q 2129 14 inhibiting inhibit VBG cord-006870-f5w6fw6q 2129 15 P2Y12 P2Y12 NNP cord-006870-f5w6fw6q 2129 16 reeceptor reeceptor NNP cord-006870-f5w6fw6q 2129 17 . . . cord-006870-f5w6fw6q 2130 1 The the DT cord-006870-f5w6fw6q 2130 2 major major JJ cord-006870-f5w6fw6q 2130 3 alleles allele NNS cord-006870-f5w6fw6q 2130 4 of of IN cord-006870-f5w6fw6q 2130 5 the the DT cord-006870-f5w6fw6q 2130 6 CYP2C19 CYP2C19 NNP cord-006870-f5w6fw6q 2130 7 gene gene NN cord-006870-f5w6fw6q 2130 8 are be VBP cord-006870-f5w6fw6q 2130 9 * * NFP cord-006870-f5w6fw6q 2130 10 1 1 CD cord-006870-f5w6fw6q 2130 11 , , , cord-006870-f5w6fw6q 2131 1 * * NFP cord-006870-f5w6fw6q 2131 2 2 2 CD cord-006870-f5w6fw6q 2131 3 , , , cord-006870-f5w6fw6q 2131 4 * * NFP cord-006870-f5w6fw6q 2131 5 3 3 CD cord-006870-f5w6fw6q 2131 6 and and CC cord-006870-f5w6fw6q 2131 7 * * NFP cord-006870-f5w6fw6q 2131 8 17 17 CD cord-006870-f5w6fw6q 2131 9 and and CC cord-006870-f5w6fw6q 2131 10 approximately approximately RB cord-006870-f5w6fw6q 2131 11 30 30 CD cord-006870-f5w6fw6q 2131 12 % % NN cord-006870-f5w6fw6q 2131 13 of of IN cord-006870-f5w6fw6q 2131 14 Caucasians Caucasians NNPS cord-006870-f5w6fw6q 2131 15 and and CC cord-006870-f5w6fw6q 2131 16 55 55 CD cord-006870-f5w6fw6q 2131 17 % % NN cord-006870-f5w6fw6q 2131 18 of of IN cord-006870-f5w6fw6q 2131 19 Asians Asians NNPS cord-006870-f5w6fw6q 2131 20 have have VBP cord-006870-f5w6fw6q 2131 21 one one CD cord-006870-f5w6fw6q 2131 22 or or CC cord-006870-f5w6fw6q 2131 23 more more JJR cord-006870-f5w6fw6q 2131 24 loss loss NN cord-006870-f5w6fw6q 2131 25 of of IN cord-006870-f5w6fw6q 2131 26 function function NN cord-006870-f5w6fw6q 2131 27 alleles allele NNS cord-006870-f5w6fw6q 2131 28 In in IN cord-006870-f5w6fw6q 2131 29 this this DT cord-006870-f5w6fw6q 2131 30 study study NN cord-006870-f5w6fw6q 2131 31 , , , cord-006870-f5w6fw6q 2131 32 patients patient NNS cord-006870-f5w6fw6q 2131 33 with with IN cord-006870-f5w6fw6q 2131 34 at at RB cord-006870-f5w6fw6q 2131 35 least least RBS cord-006870-f5w6fw6q 2131 36 two two CD cord-006870-f5w6fw6q 2131 37 * * NFP cord-006870-f5w6fw6q 2131 38 2 2 CD cord-006870-f5w6fw6q 2131 39 or or CC cord-006870-f5w6fw6q 2131 40 * * NFP cord-006870-f5w6fw6q 2131 41 3 3 CD cord-006870-f5w6fw6q 2131 42 allels allel NNS cord-006870-f5w6fw6q 2131 43 were be VBD cord-006870-f5w6fw6q 2131 44 classified classify VBN cord-006870-f5w6fw6q 2131 45 as as IN cord-006870-f5w6fw6q 2131 46 poor poor JJ cord-006870-f5w6fw6q 2131 47 metabolizer(PM metabolizer(PM NNS cord-006870-f5w6fw6q 2131 48 ) ) -RRB- cord-006870-f5w6fw6q 2131 49 , , , cord-006870-f5w6fw6q 2131 50 those those DT cord-006870-f5w6fw6q 2131 51 with with IN cord-006870-f5w6fw6q 2131 52 one one CD cord-006870-f5w6fw6q 2131 53 * * NFP cord-006870-f5w6fw6q 2131 54 2 2 CD cord-006870-f5w6fw6q 2131 55 or or CC cord-006870-f5w6fw6q 2131 56 * * NFP cord-006870-f5w6fw6q 2131 57 3 3 CD cord-006870-f5w6fw6q 2131 58 allele allele NN cord-006870-f5w6fw6q 2131 59 were be VBD cord-006870-f5w6fw6q 2131 60 classified classify VBN cord-006870-f5w6fw6q 2131 61 as as IN cord-006870-f5w6fw6q 2131 62 intermediate intermediate JJ cord-006870-f5w6fw6q 2131 63 metabolizer(IM metabolizer(IM NNP cord-006870-f5w6fw6q 2131 64 ) ) -RRB- cord-006870-f5w6fw6q 2131 65 , , , cord-006870-f5w6fw6q 2131 66 and and CC cord-006870-f5w6fw6q 2131 67 those those DT cord-006870-f5w6fw6q 2131 68 without without IN cord-006870-f5w6fw6q 2131 69 a a DT cord-006870-f5w6fw6q 2131 70 * * CD cord-006870-f5w6fw6q 2131 71 2 2 CD cord-006870-f5w6fw6q 2131 72 , , , cord-006870-f5w6fw6q 2131 73 * * NFP cord-006870-f5w6fw6q 2131 74 3 3 CD cord-006870-f5w6fw6q 2131 75 or or CC cord-006870-f5w6fw6q 2131 76 * * NFP cord-006870-f5w6fw6q 2131 77 17 17 CD cord-006870-f5w6fw6q 2131 78 alleles allele NNS cord-006870-f5w6fw6q 2131 79 were be VBD cord-006870-f5w6fw6q 2131 80 classified classify VBN cord-006870-f5w6fw6q 2131 81 as as IN cord-006870-f5w6fw6q 2131 82 extensive extensive JJ cord-006870-f5w6fw6q 2131 83 metabolizer metabolizer NN cord-006870-f5w6fw6q 2131 84 . . . cord-006870-f5w6fw6q 2132 1 In in IN cord-006870-f5w6fw6q 2132 2 addition addition NN cord-006870-f5w6fw6q 2132 3 . . . cord-006870-f5w6fw6q 2133 1 those those DT cord-006870-f5w6fw6q 2133 2 with with IN cord-006870-f5w6fw6q 2133 3 ( ( -LRB- cord-006870-f5w6fw6q 2133 4 * * NFP cord-006870-f5w6fw6q 2133 5 2/*17 2/*17 CD cord-006870-f5w6fw6q 2133 6 or or CC cord-006870-f5w6fw6q 2133 7 * * NFP cord-006870-f5w6fw6q 2133 8 3/*17 3/*17 CD cord-006870-f5w6fw6q 2133 9 ) ) -RRB- cord-006870-f5w6fw6q 2133 10 were be VBD cord-006870-f5w6fw6q 2133 11 classified classify VBN cord-006870-f5w6fw6q 2133 12 as as IN cord-006870-f5w6fw6q 2133 13 unknown unknown JJ cord-006870-f5w6fw6q 2133 14 metabolizer metabolizer NN cord-006870-f5w6fw6q 2133 15 . . . cord-006870-f5w6fw6q 2134 1 784 784 CD cord-006870-f5w6fw6q 2134 2 stroke stroke NN cord-006870-f5w6fw6q 2134 3 patients patient NNS cord-006870-f5w6fw6q 2134 4 were be VBD cord-006870-f5w6fw6q 2134 5 enrolled enrol VBN cord-006870-f5w6fw6q 2134 6 for for IN cord-006870-f5w6fw6q 2134 7 this this DT cord-006870-f5w6fw6q 2134 8 trial trial NN cord-006870-f5w6fw6q 2134 9 . . . cord-006870-f5w6fw6q 2135 1 The the DT cord-006870-f5w6fw6q 2135 2 mean mean JJ cord-006870-f5w6fw6q 2135 3 age age NN cord-006870-f5w6fw6q 2135 4 was be VBD cord-006870-f5w6fw6q 2135 5 61 61 CD cord-006870-f5w6fw6q 2135 6 years year NNS cord-006870-f5w6fw6q 2135 7 , , , cord-006870-f5w6fw6q 2135 8 and and CC cord-006870-f5w6fw6q 2135 9 32 32 CD cord-006870-f5w6fw6q 2135 10 % % NN cord-006870-f5w6fw6q 2135 11 were be VBD cord-006870-f5w6fw6q 2135 12 women woman NNS cord-006870-f5w6fw6q 2135 13 . . . cord-006870-f5w6fw6q 2136 1 61 61 CD cord-006870-f5w6fw6q 2136 2 % % NN cord-006870-f5w6fw6q 2136 3 had have VBD cord-006870-f5w6fw6q 2136 4 a a DT cord-006870-f5w6fw6q 2136 5 history history NN cord-006870-f5w6fw6q 2136 6 of of IN cord-006870-f5w6fw6q 2136 7 hypertension hypertension NN cord-006870-f5w6fw6q 2136 8 , , , cord-006870-f5w6fw6q 2136 9 29 29 CD cord-006870-f5w6fw6q 2136 10 % % NN cord-006870-f5w6fw6q 2136 11 of of IN cord-006870-f5w6fw6q 2136 12 DM DM NNP cord-006870-f5w6fw6q 2136 13 and and CC cord-006870-f5w6fw6q 2136 14 28 28 CD cord-006870-f5w6fw6q 2136 15 % % NN cord-006870-f5w6fw6q 2136 16 of of IN cord-006870-f5w6fw6q 2136 17 dyslipidemia dyslipidemia NN cord-006870-f5w6fw6q 2136 18 . . . cord-006870-f5w6fw6q 2137 1 Of of IN cord-006870-f5w6fw6q 2137 2 the the DT cord-006870-f5w6fw6q 2137 3 participants participant NNS cord-006870-f5w6fw6q 2137 4 , , , cord-006870-f5w6fw6q 2137 5 37 37 CD cord-006870-f5w6fw6q 2137 6 % % NN cord-006870-f5w6fw6q 2137 7 were be VBD cord-006870-f5w6fw6q 2137 8 classifies classifie NNS cord-006870-f5w6fw6q 2137 9 as as IN cord-006870-f5w6fw6q 2137 10 EM EM NNP cord-006870-f5w6fw6q 2137 11 , , , cord-006870-f5w6fw6q 2137 12 1 1 CD cord-006870-f5w6fw6q 2137 13 % % NN cord-006870-f5w6fw6q 2137 14 as as IN cord-006870-f5w6fw6q 2137 15 UM UM NNP cord-006870-f5w6fw6q 2137 16 , , , cord-006870-f5w6fw6q 2137 17 45 45 CD cord-006870-f5w6fw6q 2137 18 % % NN cord-006870-f5w6fw6q 2137 19 as as IN cord-006870-f5w6fw6q 2137 20 IM IM NNP cord-006870-f5w6fw6q 2137 21 , , , cord-006870-f5w6fw6q 2137 22 16 16 CD cord-006870-f5w6fw6q 2137 23 % % NN cord-006870-f5w6fw6q 2137 24 as as IN cord-006870-f5w6fw6q 2137 25 PM pm NN cord-006870-f5w6fw6q 2137 26 and and CC cord-006870-f5w6fw6q 2137 27 1 1 CD cord-006870-f5w6fw6q 2137 28 % % NN cord-006870-f5w6fw6q 2137 29 as as IN cord-006870-f5w6fw6q 2137 30 unknown unknown JJ cord-006870-f5w6fw6q 2137 31 metabolizer metabolizer NN cord-006870-f5w6fw6q 2137 32 . . . cord-006870-f5w6fw6q 2138 1 38 38 CD cord-006870-f5w6fw6q 2138 2 % % NN cord-006870-f5w6fw6q 2138 3 had have VBD cord-006870-f5w6fw6q 2138 4 good good JJ cord-006870-f5w6fw6q 2138 5 genotype genotype NN cord-006870-f5w6fw6q 2138 6 for for IN cord-006870-f5w6fw6q 2138 7 clopidogrel clopidogrel JJ cord-006870-f5w6fw6q 2138 8 metabolism metabolism NN cord-006870-f5w6fw6q 2138 9 and and CC cord-006870-f5w6fw6q 2138 10 62 62 CD cord-006870-f5w6fw6q 2138 11 % % NN cord-006870-f5w6fw6q 2138 12 had have VBD cord-006870-f5w6fw6q 2138 13 poor poor JJ cord-006870-f5w6fw6q 2138 14 genotype genotype NN cord-006870-f5w6fw6q 2138 15 . . . cord-006870-f5w6fw6q 2139 1 There there EX cord-006870-f5w6fw6q 2139 2 were be VBD cord-006870-f5w6fw6q 2139 3 no no DT cord-006870-f5w6fw6q 2139 4 significant significant JJ cord-006870-f5w6fw6q 2139 5 diffirences diffirence NNS cord-006870-f5w6fw6q 2139 6 in in IN cord-006870-f5w6fw6q 2139 7 the the DT cord-006870-f5w6fw6q 2139 8 demographic demographic JJ cord-006870-f5w6fw6q 2139 9 and and CC cord-006870-f5w6fw6q 2139 10 clinical clinical JJ cord-006870-f5w6fw6q 2139 11 findings finding NNS cord-006870-f5w6fw6q 2139 12 between between IN cord-006870-f5w6fw6q 2139 13 the the DT cord-006870-f5w6fw6q 2139 14 good good JJ cord-006870-f5w6fw6q 2139 15 and and CC cord-006870-f5w6fw6q 2139 16 poor poor JJ cord-006870-f5w6fw6q 2139 17 genotype genotype NN cord-006870-f5w6fw6q 2139 18 groups group NNS cord-006870-f5w6fw6q 2140 1 The the DT cord-006870-f5w6fw6q 2140 2 prevalence prevalence NN cord-006870-f5w6fw6q 2140 3 of of IN cord-006870-f5w6fw6q 2140 4 CYP2C19 CYP2C19 NNP cord-006870-f5w6fw6q 2140 5 polymorphisms polymorphism NNS cord-006870-f5w6fw6q 2140 6 is be VBZ cord-006870-f5w6fw6q 2140 7 different different JJ cord-006870-f5w6fw6q 2140 8 according accord VBG cord-006870-f5w6fw6q 2140 9 to to IN cord-006870-f5w6fw6q 2140 10 the the DT cord-006870-f5w6fw6q 2140 11 ethnicity ethnicity NN cord-006870-f5w6fw6q 2140 12 . . . cord-006870-f5w6fw6q 2141 1 The the DT cord-006870-f5w6fw6q 2141 2 racial racial JJ cord-006870-f5w6fw6q 2141 3 difference difference NN cord-006870-f5w6fw6q 2141 4 in in IN cord-006870-f5w6fw6q 2141 5 platelet platelet NN cord-006870-f5w6fw6q 2141 6 function function NN cord-006870-f5w6fw6q 2141 7 may may MD cord-006870-f5w6fw6q 2141 8 lead lead VB cord-006870-f5w6fw6q 2141 9 to to IN cord-006870-f5w6fw6q 2141 10 diffrerences diffrerence NNS cord-006870-f5w6fw6q 2141 11 in in IN cord-006870-f5w6fw6q 2141 12 the the DT cord-006870-f5w6fw6q 2141 13 treatment treatment NN cord-006870-f5w6fw6q 2141 14 as as RB cord-006870-f5w6fw6q 2141 15 well well RB cord-006870-f5w6fw6q 2141 16 as as IN cord-006870-f5w6fw6q 2141 17 new new JJ cord-006870-f5w6fw6q 2141 18 targets target NNS cord-006870-f5w6fw6q 2141 19 for for IN cord-006870-f5w6fw6q 2141 20 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 2141 21 therapy therapy NN cord-006870-f5w6fw6q 2142 1 The the DT cord-006870-f5w6fw6q 2142 2 social social JJ cord-006870-f5w6fw6q 2142 3 brain brain NN cord-006870-f5w6fw6q 2142 4 hypothesis hypothesis NN cord-006870-f5w6fw6q 2142 5 is be VBZ cord-006870-f5w6fw6q 2142 6 an an DT cord-006870-f5w6fw6q 2142 7 evolutionary evolutionary JJ cord-006870-f5w6fw6q 2142 8 theory theory NN cord-006870-f5w6fw6q 2142 9 proposing propose VBG cord-006870-f5w6fw6q 2142 10 that that IN cord-006870-f5w6fw6q 2142 11 the the DT cord-006870-f5w6fw6q 2142 12 number number NN cord-006870-f5w6fw6q 2142 13 of of IN cord-006870-f5w6fw6q 2142 14 contacts contact NNS cord-006870-f5w6fw6q 2142 15 in in IN cord-006870-f5w6fw6q 2142 16 a a DT cord-006870-f5w6fw6q 2142 17 primate primate NN cord-006870-f5w6fw6q 2142 18 's 's POS cord-006870-f5w6fw6q 2142 19 social social JJ cord-006870-f5w6fw6q 2142 20 network network NN cord-006870-f5w6fw6q 2142 21 is be VBZ cord-006870-f5w6fw6q 2142 22 proportional proportional JJ cord-006870-f5w6fw6q 2142 23 to to IN cord-006870-f5w6fw6q 2142 24 neocortical neocortical JJ cord-006870-f5w6fw6q 2142 25 volume volume NN cord-006870-f5w6fw6q 2142 26 . . . cord-006870-f5w6fw6q 2143 1 We -PRON- PRP cord-006870-f5w6fw6q 2143 2 tested test VBD cord-006870-f5w6fw6q 2143 3 the the DT cord-006870-f5w6fw6q 2143 4 hypothesis hypothesis NN cord-006870-f5w6fw6q 2143 5 in in IN cord-006870-f5w6fw6q 2143 6 a a DT cord-006870-f5w6fw6q 2143 7 patient patient JJ cord-006870-f5w6fw6q 2143 8 population population NN cord-006870-f5w6fw6q 2143 9 with with IN cord-006870-f5w6fw6q 2143 10 social social JJ cord-006870-f5w6fw6q 2143 11 network network NN cord-006870-f5w6fw6q 2143 12 data datum NNS cord-006870-f5w6fw6q 2143 13 before before IN cord-006870-f5w6fw6q 2143 14 and and CC cord-006870-f5w6fw6q 2143 15 after after IN cord-006870-f5w6fw6q 2143 16 vascular vascular JJ cord-006870-f5w6fw6q 2143 17 events event NNS cord-006870-f5w6fw6q 2143 18 . . . cord-006870-f5w6fw6q 2144 1 We -PRON- PRP cord-006870-f5w6fw6q 2144 2 studied study VBD cord-006870-f5w6fw6q 2144 3 whether whether IN cord-006870-f5w6fw6q 2144 4 social social JJ cord-006870-f5w6fw6q 2144 5 network network NN cord-006870-f5w6fw6q 2144 6 indices index NNS cord-006870-f5w6fw6q 2144 7 would would MD cord-006870-f5w6fw6q 2144 8 decrease decrease VB cord-006870-f5w6fw6q 2144 9 after after IN cord-006870-f5w6fw6q 2144 10 stroke stroke NN cord-006870-f5w6fw6q 2144 11 , , , cord-006870-f5w6fw6q 2144 12 but but CC cord-006870-f5w6fw6q 2144 13 not not RB cord-006870-f5w6fw6q 2144 14 after after IN cord-006870-f5w6fw6q 2144 15 myocardial myocardial JJ cord-006870-f5w6fw6q 2144 16 infarction infarction NN cord-006870-f5w6fw6q 2144 17 ( ( -LRB- cord-006870-f5w6fw6q 2144 18 MI MI NNP cord-006870-f5w6fw6q 2144 19 ) ) -RRB- cord-006870-f5w6fw6q 2144 20 , , , cord-006870-f5w6fw6q 2144 21 as as IN cord-006870-f5w6fw6q 2144 22 anticipated anticipate VBN cord-006870-f5w6fw6q 2144 23 by by IN cord-006870-f5w6fw6q 2144 24 the the DT cord-006870-f5w6fw6q 2144 25 theory theory NN cord-006870-f5w6fw6q 2144 26 . . . cord-006870-f5w6fw6q 2145 1 We -PRON- PRP cord-006870-f5w6fw6q 2145 2 examined examine VBD cord-006870-f5w6fw6q 2145 3 trajectories trajectory NNS cord-006870-f5w6fw6q 2145 4 of of IN cord-006870-f5w6fw6q 2145 5 the the DT cord-006870-f5w6fw6q 2145 6 Lubben Lubben NNP cord-006870-f5w6fw6q 2145 7 Social Social NNP cord-006870-f5w6fw6q 2145 8 Network Network NNP cord-006870-f5w6fw6q 2145 9 Scale Scale NNP cord-006870-f5w6fw6q 2145 10 score score NN cord-006870-f5w6fw6q 2145 11 ( ( -LRB- cord-006870-f5w6fw6q 2145 12 range range NN cord-006870-f5w6fw6q 2145 13 0 0 CD cord-006870-f5w6fw6q 2145 14 - - SYM cord-006870-f5w6fw6q 2145 15 50 50 CD cord-006870-f5w6fw6q 2145 16 , , , cord-006870-f5w6fw6q 2145 17 higher high JJR cord-006870-f5w6fw6q 2145 18 values value NNS cord-006870-f5w6fw6q 2145 19 indicating indicate VBG cord-006870-f5w6fw6q 2145 20 larger large JJR cord-006870-f5w6fw6q 2145 21 network network NN cord-006870-f5w6fw6q 2145 22 ) ) -RRB- cord-006870-f5w6fw6q 2145 23 before before IN cord-006870-f5w6fw6q 2145 24 and and CC cord-006870-f5w6fw6q 2145 25 after after IN cord-006870-f5w6fw6q 2145 26 vascular vascular JJ cord-006870-f5w6fw6q 2145 27 events event NNS cord-006870-f5w6fw6q 2145 28 in in IN cord-006870-f5w6fw6q 2145 29 participants participant NNS cord-006870-f5w6fw6q 2145 30 from from IN cord-006870-f5w6fw6q 2145 31 the the DT cord-006870-f5w6fw6q 2145 32 Cardiovascular Cardiovascular NNP cord-006870-f5w6fw6q 2145 33 Health Health NNP cord-006870-f5w6fw6q 2145 34 Study Study NNP cord-006870-f5w6fw6q 2145 35 . . . cord-006870-f5w6fw6q 2146 1 We -PRON- PRP cord-006870-f5w6fw6q 2146 2 used use VBD cord-006870-f5w6fw6q 2146 3 a a DT cord-006870-f5w6fw6q 2146 4 repeated repeat VBN cord-006870-f5w6fw6q 2146 5 measures measure NNS cord-006870-f5w6fw6q 2146 6 design design NN cord-006870-f5w6fw6q 2146 7 with with IN cord-006870-f5w6fw6q 2146 8 linear linear JJ cord-006870-f5w6fw6q 2146 9 mixed mixed JJ cord-006870-f5w6fw6q 2146 10 models model NNS cord-006870-f5w6fw6q 2146 11 to to TO cord-006870-f5w6fw6q 2146 12 compare compare VB cord-006870-f5w6fw6q 2146 13 the the DT cord-006870-f5w6fw6q 2146 14 change change NN cord-006870-f5w6fw6q 2146 15 in in IN cord-006870-f5w6fw6q 2146 16 social social JJ cord-006870-f5w6fw6q 2146 17 network network NN cord-006870-f5w6fw6q 2146 18 score score NN cord-006870-f5w6fw6q 2146 19 before before IN cord-006870-f5w6fw6q 2146 20 and and CC cord-006870-f5w6fw6q 2146 21 after after IN cord-006870-f5w6fw6q 2146 22 events event NNS cord-006870-f5w6fw6q 2146 23 in in IN cord-006870-f5w6fw6q 2146 24 382 382 CD cord-006870-f5w6fw6q 2146 25 persons person NNS cord-006870-f5w6fw6q 2146 26 with with IN cord-006870-f5w6fw6q 2146 27 ischemic ischemic JJ cord-006870-f5w6fw6q 2146 28 stroke stroke NN cord-006870-f5w6fw6q 2146 29 and and CC cord-006870-f5w6fw6q 2146 30 395 395 CD cord-006870-f5w6fw6q 2146 31 with with IN cord-006870-f5w6fw6q 2146 32 MI MI NNP cord-006870-f5w6fw6q 2146 33 . . . cord-006870-f5w6fw6q 2147 1 Over over IN cord-006870-f5w6fw6q 2147 2 a a DT cord-006870-f5w6fw6q 2147 3 mean mean NN cord-006870-f5w6fw6q 2147 4 of of IN cord-006870-f5w6fw6q 2147 5 11.1 11.1 CD cord-006870-f5w6fw6q 2147 6 years year NNS cord-006870-f5w6fw6q 2147 7 of of IN cord-006870-f5w6fw6q 2147 8 follow follow NN cord-006870-f5w6fw6q 2147 9 - - HYPH cord-006870-f5w6fw6q 2147 10 up up NN cord-006870-f5w6fw6q 2147 11 for for IN cord-006870-f5w6fw6q 2147 12 stroke stroke NN cord-006870-f5w6fw6q 2147 13 and and CC cord-006870-f5w6fw6q 2147 14 12.4 12.4 CD cord-006870-f5w6fw6q 2147 15 years year NNS cord-006870-f5w6fw6q 2147 16 for for IN cord-006870-f5w6fw6q 2147 17 MI MI NNP cord-006870-f5w6fw6q 2147 18 , , , cord-006870-f5w6fw6q 2147 19 we -PRON- PRP cord-006870-f5w6fw6q 2147 20 examined examine VBD cord-006870-f5w6fw6q 2147 21 an an DT cord-006870-f5w6fw6q 2147 22 average average NN cord-006870-f5w6fw6q 2147 23 of of IN cord-006870-f5w6fw6q 2147 24 4 4 CD cord-006870-f5w6fw6q 2147 25 social social JJ cord-006870-f5w6fw6q 2147 26 network network NN cord-006870-f5w6fw6q 2147 27 scores score NNS cord-006870-f5w6fw6q 2147 28 for for IN cord-006870-f5w6fw6q 2147 29 each each DT cord-006870-f5w6fw6q 2147 30 participant participant NN cord-006870-f5w6fw6q 2147 31 . . . cord-006870-f5w6fw6q 2148 1 We -PRON- PRP cord-006870-f5w6fw6q 2148 2 controlled control VBD cord-006870-f5w6fw6q 2148 3 for for IN cord-006870-f5w6fw6q 2148 4 socio socio NNS cord-006870-f5w6fw6q 2148 5 - - HYPH cord-006870-f5w6fw6q 2148 6 demographics demographic NNS cord-006870-f5w6fw6q 2148 7 , , , cord-006870-f5w6fw6q 2148 8 baseline baseline JJ cord-006870-f5w6fw6q 2148 9 cognitive cognitive JJ cord-006870-f5w6fw6q 2148 10 function function NN cord-006870-f5w6fw6q 2148 11 , , , cord-006870-f5w6fw6q 2148 12 and and CC cord-006870-f5w6fw6q 2148 13 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 2148 14 . . . cord-006870-f5w6fw6q 2149 1 Social social JJ cord-006870-f5w6fw6q 2149 2 network network NN cord-006870-f5w6fw6q 2149 3 scores score NNS cord-006870-f5w6fw6q 2149 4 declined decline VBD cord-006870-f5w6fw6q 2149 5 significantly significantly RB cord-006870-f5w6fw6q 2149 6 after after IN cord-006870-f5w6fw6q 2149 7 stroke stroke NN cord-006870-f5w6fw6q 2149 8 ( ( -LRB- cord-006870-f5w6fw6q 2149 9 an an DT cord-006870-f5w6fw6q 2149 10 additional additional JJ cord-006870-f5w6fw6q 2149 11 -0.14 -0.14 CD cord-006870-f5w6fw6q 2149 12 points point NNS cord-006870-f5w6fw6q 2149 13 every every DT cord-006870-f5w6fw6q 2149 14 year year NN cord-006870-f5w6fw6q 2149 15 , , , cord-006870-f5w6fw6q 2149 16 95 95 CD cord-006870-f5w6fw6q 2149 17 % % NN cord-006870-f5w6fw6q 2149 18 CI CI NNP cord-006870-f5w6fw6q 2149 19 -0.27 -0.27 CD cord-006870-f5w6fw6q 2149 20 , , , cord-006870-f5w6fw6q 2149 21 -0.01 -0.01 CD cord-006870-f5w6fw6q 2149 22 , , , cord-006870-f5w6fw6q 2149 23 P=0.04 P=0.04 NNP cord-006870-f5w6fw6q 2149 24 ) ) -RRB- cord-006870-f5w6fw6q 2149 25 , , , cord-006870-f5w6fw6q 2149 26 but but CC cord-006870-f5w6fw6q 2149 27 not not RB cord-006870-f5w6fw6q 2149 28 after after IN cord-006870-f5w6fw6q 2149 29 MI MI NNP cord-006870-f5w6fw6q 2149 30 ( ( -LRB- cord-006870-f5w6fw6q 2149 31 -0.06 -0.06 CD cord-006870-f5w6fw6q 2149 32 , , , cord-006870-f5w6fw6q 2149 33 95 95 CD cord-006870-f5w6fw6q 2149 34 % % NN cord-006870-f5w6fw6q 2149 35 CI CI NNP cord-006870-f5w6fw6q 2149 36 -0.16 -0.16 CD cord-006870-f5w6fw6q 2149 37 , , , cord-006870-f5w6fw6q 2149 38 0.04 0.04 CD cord-006870-f5w6fw6q 2149 39 , , , cord-006870-f5w6fw6q 2149 40 P=0.24 P=0.24 NNP cord-006870-f5w6fw6q 2149 41 ) ) -RRB- cord-006870-f5w6fw6q 2149 42 compared compare VBN cord-006870-f5w6fw6q 2149 43 to to IN cord-006870-f5w6fw6q 2149 44 the the DT cord-006870-f5w6fw6q 2149 45 baseline baseline JJ cord-006870-f5w6fw6q 2149 46 slope slope NN cord-006870-f5w6fw6q 2149 47 in in IN cord-006870-f5w6fw6q 2149 48 fully fully RB cord-006870-f5w6fw6q 2149 49 adjusted adjust VBN cord-006870-f5w6fw6q 2149 50 models model NNS cord-006870-f5w6fw6q 2149 51 . . . cord-006870-f5w6fw6q 2150 1 Social social JJ cord-006870-f5w6fw6q 2150 2 network network NN cord-006870-f5w6fw6q 2150 3 score score NN cord-006870-f5w6fw6q 2150 4 declined decline VBD cord-006870-f5w6fw6q 2150 5 more more RBR cord-006870-f5w6fw6q 2150 6 steeply steeply RB cord-006870-f5w6fw6q 2150 7 after after IN cord-006870-f5w6fw6q 2150 8 stroke stroke NN cord-006870-f5w6fw6q 2150 9 than than IN cord-006870-f5w6fw6q 2150 10 after after IN cord-006870-f5w6fw6q 2150 11 MI MI NNP cord-006870-f5w6fw6q 2150 12 , , , cord-006870-f5w6fw6q 2150 13 even even RB cord-006870-f5w6fw6q 2150 14 after after IN cord-006870-f5w6fw6q 2150 15 adjusting adjust VBG cord-006870-f5w6fw6q 2150 16 for for IN cord-006870-f5w6fw6q 2150 17 potential potential JJ cord-006870-f5w6fw6q 2150 18 confounders confounder NNS cord-006870-f5w6fw6q 2150 19 . . . cord-006870-f5w6fw6q 2151 1 These these DT cord-006870-f5w6fw6q 2151 2 findings finding NNS cord-006870-f5w6fw6q 2151 3 support support VBP cord-006870-f5w6fw6q 2151 4 the the DT cord-006870-f5w6fw6q 2151 5 social social JJ cord-006870-f5w6fw6q 2151 6 brain brain NN cord-006870-f5w6fw6q 2151 7 hypothesis hypothesis NN cord-006870-f5w6fw6q 2151 8 but but CC cord-006870-f5w6fw6q 2151 9 do do VBP cord-006870-f5w6fw6q 2151 10 not not RB cord-006870-f5w6fw6q 2151 11 address address VB cord-006870-f5w6fw6q 2151 12 mechanism mechanism NN cord-006870-f5w6fw6q 2151 13 . . . cord-006870-f5w6fw6q 2152 1 Shrinkage shrinkage NN cord-006870-f5w6fw6q 2152 2 of of IN cord-006870-f5w6fw6q 2152 3 the the DT cord-006870-f5w6fw6q 2152 4 social social JJ cord-006870-f5w6fw6q 2152 5 networks network NNS cord-006870-f5w6fw6q 2152 6 may may MD cord-006870-f5w6fw6q 2152 7 be be VB cord-006870-f5w6fw6q 2152 8 a a DT cord-006870-f5w6fw6q 2152 9 specific specific JJ cord-006870-f5w6fw6q 2152 10 target target NN cord-006870-f5w6fw6q 2152 11 for for IN cord-006870-f5w6fw6q 2152 12 interventions intervention NNS cord-006870-f5w6fw6q 2152 13 to to TO cord-006870-f5w6fw6q 2152 14 optimize optimize VB cord-006870-f5w6fw6q 2152 15 recovery recovery NN cord-006870-f5w6fw6q 2152 16 in in IN cord-006870-f5w6fw6q 2152 17 vascular vascular JJ cord-006870-f5w6fw6q 2152 18 diseases disease NNS cord-006870-f5w6fw6q 2152 19 , , , cord-006870-f5w6fw6q 2152 20 particularly particularly RB cord-006870-f5w6fw6q 2152 21 stroke stroke NN cord-006870-f5w6fw6q 2152 22 . . . cord-006870-f5w6fw6q 2153 1 Emergency Emergency NNP cord-006870-f5w6fw6q 2153 2 Neurological Neurological NNP cord-006870-f5w6fw6q 2153 3 Life Life NNP cord-006870-f5w6fw6q 2153 4 Support Support NNP cord-006870-f5w6fw6q 2153 5 ( ( -LRB- cord-006870-f5w6fw6q 2153 6 ENLS ENLS NNP cord-006870-f5w6fw6q 2153 7 ) ) -RRB- cord-006870-f5w6fw6q 2153 8 protocols protocol NNS cord-006870-f5w6fw6q 2153 9 are be VBP cord-006870-f5w6fw6q 2153 10 an an DT cord-006870-f5w6fw6q 2153 11 essential essential JJ cord-006870-f5w6fw6q 2153 12 component component NN cord-006870-f5w6fw6q 2153 13 to to IN cord-006870-f5w6fw6q 2153 14 assessment assessment NN cord-006870-f5w6fw6q 2153 15 and and CC cord-006870-f5w6fw6q 2153 16 management management NN cord-006870-f5w6fw6q 2153 17 of of IN cord-006870-f5w6fw6q 2153 18 patients patient NNS cord-006870-f5w6fw6q 2153 19 within within IN cord-006870-f5w6fw6q 2153 20 the the DT cord-006870-f5w6fw6q 2153 21 first first JJ cord-006870-f5w6fw6q 2153 22 hours hour NNS cord-006870-f5w6fw6q 2153 23 of of IN cord-006870-f5w6fw6q 2153 24 the the DT cord-006870-f5w6fw6q 2153 25 neurological neurological JJ cord-006870-f5w6fw6q 2153 26 emergency emergency NN cord-006870-f5w6fw6q 2153 27 . . . cord-006870-f5w6fw6q 2154 1 With with IN cord-006870-f5w6fw6q 2154 2 increasing increase VBG cord-006870-f5w6fw6q 2154 3 focus focus NN cord-006870-f5w6fw6q 2154 4 on on IN cord-006870-f5w6fw6q 2154 5 emergent emergent JJ cord-006870-f5w6fw6q 2154 6 endovascular endovascular JJ cord-006870-f5w6fw6q 2154 7 treatment treatment NN cord-006870-f5w6fw6q 2154 8 for for IN cord-006870-f5w6fw6q 2154 9 large large JJ cord-006870-f5w6fw6q 2154 10 vessel vessel NN cord-006870-f5w6fw6q 2154 11 occlusion occlusion NN cord-006870-f5w6fw6q 2154 12 ( ( -LRB- cord-006870-f5w6fw6q 2154 13 LVO LVO NNP cord-006870-f5w6fw6q 2154 14 ) ) -RRB- cord-006870-f5w6fw6q 2154 15 in in IN cord-006870-f5w6fw6q 2154 16 acute acute JJ cord-006870-f5w6fw6q 2154 17 ischemic ischemic JJ cord-006870-f5w6fw6q 2154 18 stroke stroke NN cord-006870-f5w6fw6q 2154 19 our -PRON- PRP$ cord-006870-f5w6fw6q 2154 20 institution institution NN cord-006870-f5w6fw6q 2154 21 incorporated incorporate VBD cord-006870-f5w6fw6q 2154 22 Stroke Stroke NNP cord-006870-f5w6fw6q 2154 23 VAN VAN NNP cord-006870-f5w6fw6q 2154 24 assessment assessment NN cord-006870-f5w6fw6q 2154 25 as as IN cord-006870-f5w6fw6q 2154 26 part part NN cord-006870-f5w6fw6q 2154 27 of of IN cord-006870-f5w6fw6q 2154 28 the the DT cord-006870-f5w6fw6q 2154 29 ENLS ENLS NNP cord-006870-f5w6fw6q 2154 30 Acute Acute NNP cord-006870-f5w6fw6q 2154 31 Stroke Stroke NNP cord-006870-f5w6fw6q 2154 32 Initial Initial NNP cord-006870-f5w6fw6q 2154 33 Assessment Assessment NNP cord-006870-f5w6fw6q 2154 34 protocol protocol NN cord-006870-f5w6fw6q 2154 35 . . . cord-006870-f5w6fw6q 2155 1 Stroke stroke NN cord-006870-f5w6fw6q 2155 2 VAN VAN NNP cord-006870-f5w6fw6q 2155 3 screening screening NN cord-006870-f5w6fw6q 2155 4 tool tool NN cord-006870-f5w6fw6q 2155 5 was be VBD cord-006870-f5w6fw6q 2155 6 taught teach VBN cord-006870-f5w6fw6q 2155 7 to to IN cord-006870-f5w6fw6q 2155 8 all all DT cord-006870-f5w6fw6q 2155 9 nurses nurse NNS cord-006870-f5w6fw6q 2155 10 in in IN cord-006870-f5w6fw6q 2155 11 the the DT cord-006870-f5w6fw6q 2155 12 Emergency Emergency NNP cord-006870-f5w6fw6q 2155 13 Department Department NNP cord-006870-f5w6fw6q 2155 14 ( ( -LRB- cord-006870-f5w6fw6q 2155 15 ED ED NNP cord-006870-f5w6fw6q 2155 16 ) ) -RRB- cord-006870-f5w6fw6q 2155 17 who who WP cord-006870-f5w6fw6q 2155 18 triage triage VBP cord-006870-f5w6fw6q 2155 19 stroke stroke NN cord-006870-f5w6fw6q 2155 20 . . . cord-006870-f5w6fw6q 2156 1 All all DT cord-006870-f5w6fw6q 2156 2 patients patient NNS cord-006870-f5w6fw6q 2156 3 who who WP cord-006870-f5w6fw6q 2156 4 presented present VBD cord-006870-f5w6fw6q 2156 5 to to IN cord-006870-f5w6fw6q 2156 6 the the DT cord-006870-f5w6fw6q 2156 7 ED ED NNP cord-006870-f5w6fw6q 2156 8 with with IN cord-006870-f5w6fw6q 2156 9 suspected suspect VBN cord-006870-f5w6fw6q 2156 10 stroke stroke NN cord-006870-f5w6fw6q 2156 11 had have VBD cord-006870-f5w6fw6q 2156 12 a a DT cord-006870-f5w6fw6q 2156 13 VAN VAN NNP cord-006870-f5w6fw6q 2156 14 assessment assessment NN cord-006870-f5w6fw6q 2156 15 completed complete VBN cord-006870-f5w6fw6q 2156 16 prior prior RB cord-006870-f5w6fw6q 2156 17 to to IN cord-006870-f5w6fw6q 2156 18 ED ED NNP cord-006870-f5w6fw6q 2156 19 physician physician NN cord-006870-f5w6fw6q 2156 20 evaluation evaluation NN cord-006870-f5w6fw6q 2156 21 and and CC cord-006870-f5w6fw6q 2156 22 CT CT NNP cord-006870-f5w6fw6q 2156 23 imaging imaging NN cord-006870-f5w6fw6q 2156 24 . . . cord-006870-f5w6fw6q 2157 1 Patients patient NNS cord-006870-f5w6fw6q 2157 2 with with IN cord-006870-f5w6fw6q 2157 3 weakness weakness NN cord-006870-f5w6fw6q 2157 4 in in IN cord-006870-f5w6fw6q 2157 5 addition addition NN cord-006870-f5w6fw6q 2157 6 to to IN cord-006870-f5w6fw6q 2157 7 visual visual JJ cord-006870-f5w6fw6q 2157 8 changes change NNS cord-006870-f5w6fw6q 2157 9 , , , cord-006870-f5w6fw6q 2157 10 aphasia aphasia NNP cord-006870-f5w6fw6q 2157 11 , , , cord-006870-f5w6fw6q 2157 12 or or CC cord-006870-f5w6fw6q 2157 13 neglect neglect NN cord-006870-f5w6fw6q 2157 14 were be VBD cord-006870-f5w6fw6q 2157 15 considered consider VBN cord-006870-f5w6fw6q 2157 16 VAN van NN cord-006870-f5w6fw6q 2157 17 + + SYM cord-006870-f5w6fw6q 2157 18 and and CC cord-006870-f5w6fw6q 2157 19 triaged triage VBD cord-006870-f5w6fw6q 2157 20 immediately immediately RB cord-006870-f5w6fw6q 2157 21 to to IN cord-006870-f5w6fw6q 2157 22 CT CT NNP cord-006870-f5w6fw6q 2157 23 angiogram angiogram NN cord-006870-f5w6fw6q 2157 24 head head NN cord-006870-f5w6fw6q 2157 25 / / SYM cord-006870-f5w6fw6q 2157 26 neck neck NN cord-006870-f5w6fw6q 2157 27 with with IN cord-006870-f5w6fw6q 2157 28 immediate immediate JJ cord-006870-f5w6fw6q 2157 29 notification notification NN cord-006870-f5w6fw6q 2157 30 to to IN cord-006870-f5w6fw6q 2157 31 the the DT cord-006870-f5w6fw6q 2157 32 Neurointerventionalist Neurointerventionalist NNP cord-006870-f5w6fw6q 2157 33 . . . cord-006870-f5w6fw6q 2158 1 A a DT cord-006870-f5w6fw6q 2158 2 sample sample NN cord-006870-f5w6fw6q 2158 3 of of IN cord-006870-f5w6fw6q 2158 4 76 76 CD cord-006870-f5w6fw6q 2158 5 patients patient NNS cord-006870-f5w6fw6q 2158 6 presenting present VBG cord-006870-f5w6fw6q 2158 7 to to IN cord-006870-f5w6fw6q 2158 8 the the DT cord-006870-f5w6fw6q 2158 9 ED ED NNP cord-006870-f5w6fw6q 2158 10 as as IN cord-006870-f5w6fw6q 2158 11 a a DT cord-006870-f5w6fw6q 2158 12 stroke stroke NN cord-006870-f5w6fw6q 2158 13 alert alert NN cord-006870-f5w6fw6q 2158 14 over over IN cord-006870-f5w6fw6q 2158 15 an an DT cord-006870-f5w6fw6q 2158 16 8 8 CD cord-006870-f5w6fw6q 2158 17 month month NN cord-006870-f5w6fw6q 2158 18 time time NN cord-006870-f5w6fw6q 2158 19 period period NN cord-006870-f5w6fw6q 2158 20 were be VBD cord-006870-f5w6fw6q 2158 21 utilized utilize VBN cord-006870-f5w6fw6q 2158 22 . . . cord-006870-f5w6fw6q 2159 1 Using use VBG cord-006870-f5w6fw6q 2159 2 the the DT cord-006870-f5w6fw6q 2159 3 Stroke Stroke NNP cord-006870-f5w6fw6q 2159 4 VAN VAN NNP cord-006870-f5w6fw6q 2159 5 assessment assessment NN cord-006870-f5w6fw6q 2159 6 tool tool NN cord-006870-f5w6fw6q 2159 7 was be VBD cord-006870-f5w6fw6q 2159 8 found find VBN cord-006870-f5w6fw6q 2159 9 to to TO cord-006870-f5w6fw6q 2159 10 improve improve VB cord-006870-f5w6fw6q 2159 11 time time NN cord-006870-f5w6fw6q 2159 12 to to IN cord-006870-f5w6fw6q 2159 13 identification identification NN cord-006870-f5w6fw6q 2159 14 of of IN cord-006870-f5w6fw6q 2159 15 LVO LVO NNP cord-006870-f5w6fw6q 2159 16 by by IN cord-006870-f5w6fw6q 2159 17 reducing reduce VBG cord-006870-f5w6fw6q 2159 18 time time NN cord-006870-f5w6fw6q 2159 19 from from IN cord-006870-f5w6fw6q 2159 20 arrival arrival NN cord-006870-f5w6fw6q 2159 21 to to IN cord-006870-f5w6fw6q 2159 22 CTA CTA NNP cord-006870-f5w6fw6q 2159 23 for for IN cord-006870-f5w6fw6q 2159 24 VAN VAN NNP cord-006870-f5w6fw6q 2159 25 positive positive JJ cord-006870-f5w6fw6q 2159 26 patients patient NNS cord-006870-f5w6fw6q 2159 27 from from IN cord-006870-f5w6fw6q 2159 28 77 77 CD cord-006870-f5w6fw6q 2159 29 minutes minute NNS cord-006870-f5w6fw6q 2159 30 pre pre NN cord-006870-f5w6fw6q 2159 31 - - NN cord-006870-f5w6fw6q 2159 32 intervention intervention JJ cord-006870-f5w6fw6q 2159 33 ( ( -LRB- cord-006870-f5w6fw6q 2159 34 n=31 n=31 NNP cord-006870-f5w6fw6q 2159 35 ) ) -RRB- cord-006870-f5w6fw6q 2159 36 to to IN cord-006870-f5w6fw6q 2159 37 27 27 CD cord-006870-f5w6fw6q 2159 38 minutes minute NNS cord-006870-f5w6fw6q 2159 39 post post NN cord-006870-f5w6fw6q 2159 40 - - NN cord-006870-f5w6fw6q 2159 41 intervention intervention JJ cord-006870-f5w6fw6q 2159 42 ( ( -LRB- cord-006870-f5w6fw6q 2159 43 n=35 n=35 NNP cord-006870-f5w6fw6q 2159 44 ) ) -RRB- cord-006870-f5w6fw6q 2159 45 . . . cord-006870-f5w6fw6q 2160 1 This this DT cord-006870-f5w6fw6q 2160 2 was be VBD cord-006870-f5w6fw6q 2160 3 a a DT cord-006870-f5w6fw6q 2160 4 significant significant JJ cord-006870-f5w6fw6q 2160 5 decrease decrease NN cord-006870-f5w6fw6q 2160 6 in in IN cord-006870-f5w6fw6q 2160 7 time time NN cord-006870-f5w6fw6q 2160 8 to to IN cord-006870-f5w6fw6q 2160 9 identification identification NN cord-006870-f5w6fw6q 2160 10 of of IN cord-006870-f5w6fw6q 2160 11 patients patient NNS cord-006870-f5w6fw6q 2160 12 presenting present VBG cord-006870-f5w6fw6q 2160 13 with with IN cord-006870-f5w6fw6q 2160 14 LVO LVO NNP cord-006870-f5w6fw6q 2160 15 ( ( -LRB- cord-006870-f5w6fw6q 2160 16 p<0.05 p<0.05 NNP cord-006870-f5w6fw6q 2160 17 ) ) -RRB- cord-006870-f5w6fw6q 2160 18 , , , cord-006870-f5w6fw6q 2160 19 improving improve VBG cord-006870-f5w6fw6q 2160 20 time time NN cord-006870-f5w6fw6q 2160 21 to to IN cord-006870-f5w6fw6q 2160 22 endovascular endovascular JJ cord-006870-f5w6fw6q 2160 23 treatment treatment NN cord-006870-f5w6fw6q 2160 24 . . . cord-006870-f5w6fw6q 2161 1 Incorporating incorporate VBG cord-006870-f5w6fw6q 2161 2 Stroke Stroke NNP cord-006870-f5w6fw6q 2161 3 VAN VAN NNP cord-006870-f5w6fw6q 2161 4 as as IN cord-006870-f5w6fw6q 2161 5 part part NN cord-006870-f5w6fw6q 2161 6 of of IN cord-006870-f5w6fw6q 2161 7 the the DT cord-006870-f5w6fw6q 2161 8 Acute Acute NNP cord-006870-f5w6fw6q 2161 9 Stroke Stroke NNP cord-006870-f5w6fw6q 2161 10 Assessment Assessment NNP cord-006870-f5w6fw6q 2161 11 Protocol Protocol NNP cord-006870-f5w6fw6q 2161 12 improved improve VBD cord-006870-f5w6fw6q 2161 13 identification identification NN cord-006870-f5w6fw6q 2161 14 of of IN cord-006870-f5w6fw6q 2161 15 patients patient NNS cord-006870-f5w6fw6q 2161 16 presenting present VBG cord-006870-f5w6fw6q 2161 17 with with IN cord-006870-f5w6fw6q 2161 18 LVO LVO NNP cord-006870-f5w6fw6q 2161 19 , , , cord-006870-f5w6fw6q 2161 20 decreased decrease VBD cord-006870-f5w6fw6q 2161 21 time time NN cord-006870-f5w6fw6q 2161 22 to to IN cord-006870-f5w6fw6q 2161 23 CTA CTA NNP cord-006870-f5w6fw6q 2161 24 imaging imaging NN cord-006870-f5w6fw6q 2161 25 and and CC cord-006870-f5w6fw6q 2161 26 improved improved JJ cord-006870-f5w6fw6q 2161 27 time time NN cord-006870-f5w6fw6q 2161 28 to to IN cord-006870-f5w6fw6q 2161 29 endovascular endovascular JJ cord-006870-f5w6fw6q 2161 30 treatment treatment NN cord-006870-f5w6fw6q 2161 31 which which WDT cord-006870-f5w6fw6q 2161 32 is be VBZ cord-006870-f5w6fw6q 2161 33 well well RB cord-006870-f5w6fw6q 2161 34 documented document VBN cord-006870-f5w6fw6q 2161 35 with with IN cord-006870-f5w6fw6q 2161 36 improved improve VBN cord-006870-f5w6fw6q 2161 37 neurological neurological JJ cord-006870-f5w6fw6q 2161 38 prognosis prognosis NN cord-006870-f5w6fw6q 2161 39 . . . cord-006870-f5w6fw6q 2162 1 Time time NN cord-006870-f5w6fw6q 2162 2 is be VBZ cord-006870-f5w6fw6q 2162 3 essential essential JJ cord-006870-f5w6fw6q 2162 4 in in IN cord-006870-f5w6fw6q 2162 5 neurological neurological JJ cord-006870-f5w6fw6q 2162 6 emergencies emergency NNS cord-006870-f5w6fw6q 2162 7 . . . cord-006870-f5w6fw6q 2163 1 The the DT cord-006870-f5w6fw6q 2163 2 VAN VAN NNP cord-006870-f5w6fw6q 2163 3 assessment assessment NN cord-006870-f5w6fw6q 2163 4 is be VBZ cord-006870-f5w6fw6q 2163 5 quick quick JJ cord-006870-f5w6fw6q 2163 6 and and CC cord-006870-f5w6fw6q 2163 7 easy easy JJ cord-006870-f5w6fw6q 2163 8 to to TO cord-006870-f5w6fw6q 2163 9 perform perform VB cord-006870-f5w6fw6q 2163 10 , , , cord-006870-f5w6fw6q 2163 11 requires require VBZ cord-006870-f5w6fw6q 2163 12 no no DT cord-006870-f5w6fw6q 2163 13 scoring scoring NN cord-006870-f5w6fw6q 2163 14 or or CC cord-006870-f5w6fw6q 2163 15 calculations calculation NNS cord-006870-f5w6fw6q 2163 16 , , , cord-006870-f5w6fw6q 2163 17 and and CC cord-006870-f5w6fw6q 2163 18 is be VBZ cord-006870-f5w6fw6q 2163 19 the the DT cord-006870-f5w6fw6q 2163 20 only only JJ cord-006870-f5w6fw6q 2163 21 LVO LVO NNP cord-006870-f5w6fw6q 2163 22 screening screening NN cord-006870-f5w6fw6q 2163 23 tool tool NN cord-006870-f5w6fw6q 2163 24 tested test VBN cord-006870-f5w6fw6q 2163 25 in in IN cord-006870-f5w6fw6q 2163 26 the the DT cord-006870-f5w6fw6q 2163 27 ED ED NNP cord-006870-f5w6fw6q 2163 28 by by IN cord-006870-f5w6fw6q 2163 29 ED ED NNP cord-006870-f5w6fw6q 2163 30 nurse nurse NN cord-006870-f5w6fw6q 2163 31 and and CC cord-006870-f5w6fw6q 2163 32 physicians physician NNS cord-006870-f5w6fw6q 2163 33 . . . cord-006870-f5w6fw6q 2164 1 We -PRON- PRP cord-006870-f5w6fw6q 2164 2 suggest suggest VBP cord-006870-f5w6fw6q 2164 3 incorporating incorporate VBG cord-006870-f5w6fw6q 2164 4 Stroke Stroke NNP cord-006870-f5w6fw6q 2164 5 VAN VAN NNP cord-006870-f5w6fw6q 2164 6 to to IN cord-006870-f5w6fw6q 2164 7 the the DT cord-006870-f5w6fw6q 2164 8 ENLS ENLS NNP cord-006870-f5w6fw6q 2164 9 Acute Acute NNP cord-006870-f5w6fw6q 2164 10 Stroke Stroke NNP cord-006870-f5w6fw6q 2164 11 protocol protocol NN cord-006870-f5w6fw6q 2164 12 as as IN cord-006870-f5w6fw6q 2164 13 a a DT cord-006870-f5w6fw6q 2164 14 way way NN cord-006870-f5w6fw6q 2164 15 to to TO cord-006870-f5w6fw6q 2164 16 improve improve VB cord-006870-f5w6fw6q 2164 17 identification identification NN cord-006870-f5w6fw6q 2164 18 of of IN cord-006870-f5w6fw6q 2164 19 LVO LVO NNP cord-006870-f5w6fw6q 2164 20 and and CC cord-006870-f5w6fw6q 2164 21 improve improve VB cord-006870-f5w6fw6q 2164 22 time time NN cord-006870-f5w6fw6q 2164 23 to to IN cord-006870-f5w6fw6q 2164 24 endovascular endovascular JJ cord-006870-f5w6fw6q 2164 25 treatment treatment NN cord-006870-f5w6fw6q 2164 26 . . . cord-006870-f5w6fw6q 2165 1 Elevated Elevated NNP cord-006870-f5w6fw6q 2165 2 Blood Blood NNP cord-006870-f5w6fw6q 2165 3 pressure pressure NN cord-006870-f5w6fw6q 2165 4 ( ( -LRB- cord-006870-f5w6fw6q 2165 5 BP BP NNP cord-006870-f5w6fw6q 2165 6 ) ) -RRB- cord-006870-f5w6fw6q 2165 7 is be VBZ cord-006870-f5w6fw6q 2165 8 known know VBN cord-006870-f5w6fw6q 2165 9 to to TO cord-006870-f5w6fw6q 2165 10 be be VB cord-006870-f5w6fw6q 2165 11 related relate VBN cord-006870-f5w6fw6q 2165 12 to to IN cord-006870-f5w6fw6q 2165 13 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 2165 14 transformation transformation NN cord-006870-f5w6fw6q 2165 15 ( ( -LRB- cord-006870-f5w6fw6q 2165 16 HT HT NNP cord-006870-f5w6fw6q 2165 17 ) ) -RRB- cord-006870-f5w6fw6q 2165 18 after after IN cord-006870-f5w6fw6q 2165 19 ischemic ischemic JJ cord-006870-f5w6fw6q 2165 20 stroke stroke NN cord-006870-f5w6fw6q 2165 21 . . . cord-006870-f5w6fw6q 2166 1 However however RB cord-006870-f5w6fw6q 2166 2 , , , cord-006870-f5w6fw6q 2166 3 the the DT cord-006870-f5w6fw6q 2166 4 effect effect NN cord-006870-f5w6fw6q 2166 5 of of IN cord-006870-f5w6fw6q 2166 6 BP BP NNP cord-006870-f5w6fw6q 2166 7 variation variation NN cord-006870-f5w6fw6q 2166 8 on on IN cord-006870-f5w6fw6q 2166 9 the the DT cord-006870-f5w6fw6q 2166 10 HT HT NNP cord-006870-f5w6fw6q 2166 11 remains remain VBZ cord-006870-f5w6fw6q 2166 12 unclear unclear JJ cord-006870-f5w6fw6q 2166 13 , , , cord-006870-f5w6fw6q 2166 14 especially especially RB cord-006870-f5w6fw6q 2166 15 in in IN cord-006870-f5w6fw6q 2166 16 patients patient NNS cord-006870-f5w6fw6q 2166 17 with with IN cord-006870-f5w6fw6q 2166 18 successful successful JJ cord-006870-f5w6fw6q 2166 19 recanalization recanalization NN cord-006870-f5w6fw6q 2166 20 after after IN cord-006870-f5w6fw6q 2166 21 mechanical mechanical JJ cord-006870-f5w6fw6q 2166 22 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 2166 23 . . . cord-006870-f5w6fw6q 2167 1 Therefore therefore RB cord-006870-f5w6fw6q 2167 2 , , , cord-006870-f5w6fw6q 2167 3 we -PRON- PRP cord-006870-f5w6fw6q 2167 4 investigated investigate VBD cord-006870-f5w6fw6q 2167 5 the the DT cord-006870-f5w6fw6q 2167 6 relationship relationship NN cord-006870-f5w6fw6q 2167 7 between between IN cord-006870-f5w6fw6q 2167 8 BP BP NNP cord-006870-f5w6fw6q 2167 9 and and CC cord-006870-f5w6fw6q 2167 10 HT HT NNP cord-006870-f5w6fw6q 2167 11 after after IN cord-006870-f5w6fw6q 2167 12 mechanical mechanical JJ cord-006870-f5w6fw6q 2167 13 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 2167 14 following follow VBG cord-006870-f5w6fw6q 2167 15 ischemic ischemic JJ cord-006870-f5w6fw6q 2167 16 stroke stroke NN cord-006870-f5w6fw6q 2167 17 . . . cord-006870-f5w6fw6q 2168 1 A a DT cord-006870-f5w6fw6q 2168 2 consecutive consecutive JJ cord-006870-f5w6fw6q 2168 3 141 141 CD cord-006870-f5w6fw6q 2168 4 patients patient NNS cord-006870-f5w6fw6q 2168 5 with with IN cord-006870-f5w6fw6q 2168 6 acute acute JJ cord-006870-f5w6fw6q 2168 7 ischemic ischemic JJ cord-006870-f5w6fw6q 2168 8 stroke stroke NN cord-006870-f5w6fw6q 2168 9 and and CC cord-006870-f5w6fw6q 2168 10 successful successful JJ cord-006870-f5w6fw6q 2168 11 recanalization recanalization NN cord-006870-f5w6fw6q 2168 12 ( ( -LRB- cord-006870-f5w6fw6q 2168 13 TICI TICI NNP cord-006870-f5w6fw6q 2168 14 2b 2b CD cord-006870-f5w6fw6q 2168 15 or or CC cord-006870-f5w6fw6q 2168 16 TICI TICI NNP cord-006870-f5w6fw6q 2168 17 3 3 CD cord-006870-f5w6fw6q 2168 18 ) ) -RRB- cord-006870-f5w6fw6q 2168 19 were be VBD cord-006870-f5w6fw6q 2168 20 included include VBN cord-006870-f5w6fw6q 2168 21 for for IN cord-006870-f5w6fw6q 2168 22 the the DT cord-006870-f5w6fw6q 2168 23 analysis analysis NN cord-006870-f5w6fw6q 2168 24 between between IN cord-006870-f5w6fw6q 2168 25 January January NNP cord-006870-f5w6fw6q 2168 26 2013 2013 CD cord-006870-f5w6fw6q 2168 27 and and CC cord-006870-f5w6fw6q 2168 28 November November NNP cord-006870-f5w6fw6q 2168 29 2016 2016 CD cord-006870-f5w6fw6q 2168 30 . . . cord-006870-f5w6fw6q 2169 1 The the DT cord-006870-f5w6fw6q 2169 2 information information NN cord-006870-f5w6fw6q 2169 3 on on IN cord-006870-f5w6fw6q 2169 4 BP BP NNP cord-006870-f5w6fw6q 2169 5 was be VBD cord-006870-f5w6fw6q 2169 6 obtained obtain VBN cord-006870-f5w6fw6q 2169 7 over over IN cord-006870-f5w6fw6q 2169 8 the the DT cord-006870-f5w6fw6q 2169 9 first first JJ cord-006870-f5w6fw6q 2169 10 24 24 CD cord-006870-f5w6fw6q 2169 11 hours hour NNS cord-006870-f5w6fw6q 2169 12 using use VBG cord-006870-f5w6fw6q 2169 13 various various JJ cord-006870-f5w6fw6q 2169 14 parameters parameter NNS cord-006870-f5w6fw6q 2169 15 including include VBG cord-006870-f5w6fw6q 2169 16 mean mean VB cord-006870-f5w6fw6q 2169 17 , , , cord-006870-f5w6fw6q 2169 18 maximum maximum JJ cord-006870-f5w6fw6q 2169 19 ( ( -LRB- cord-006870-f5w6fw6q 2169 20 max max NNP cord-006870-f5w6fw6q 2169 21 ) ) -RRB- cord-006870-f5w6fw6q 2169 22 , , , cord-006870-f5w6fw6q 2169 23 minimum minimum NN cord-006870-f5w6fw6q 2169 24 ( ( -LRB- cord-006870-f5w6fw6q 2169 25 CV CV NNP cord-006870-f5w6fw6q 2169 26 ) ) -RRB- cord-006870-f5w6fw6q 2169 27 , , , cord-006870-f5w6fw6q 2169 28 and and CC cord-006870-f5w6fw6q 2169 29 successive successive JJ cord-006870-f5w6fw6q 2169 30 variations variation NNS cord-006870-f5w6fw6q 2169 31 ( ( -LRB- cord-006870-f5w6fw6q 2169 32 SV sv NN cord-006870-f5w6fw6q 2169 33 ) ) -RRB- cord-006870-f5w6fw6q 2169 34 for for IN cord-006870-f5w6fw6q 2169 35 systolic systolic JJ cord-006870-f5w6fw6q 2169 36 , , , cord-006870-f5w6fw6q 2169 37 diastolic diastolic JJ cord-006870-f5w6fw6q 2169 38 BP BP NNP cord-006870-f5w6fw6q 2169 39 , , , cord-006870-f5w6fw6q 2169 40 and and CC cord-006870-f5w6fw6q 2170 1 mean mean VB cord-006870-f5w6fw6q 2170 2 BP BP NNP cord-006870-f5w6fw6q 2170 3 . . . cord-006870-f5w6fw6q 2171 1 We -PRON- PRP cord-006870-f5w6fw6q 2171 2 defined define VBD cord-006870-f5w6fw6q 2171 3 major major JJ cord-006870-f5w6fw6q 2171 4 HT ht NN cord-006870-f5w6fw6q 2171 5 as as IN cord-006870-f5w6fw6q 2171 6 a a DT cord-006870-f5w6fw6q 2171 7 parenchymal parenchymal NN cord-006870-f5w6fw6q 2171 8 hematoma hematoma NN cord-006870-f5w6fw6q 2171 9 type type NN cord-006870-f5w6fw6q 2171 10 2 2 CD cord-006870-f5w6fw6q 2171 11 ( ( -LRB- cord-006870-f5w6fw6q 2171 12 PH2 PH2 NNP cord-006870-f5w6fw6q 2171 13 ) ) -RRB- cord-006870-f5w6fw6q 2171 14 . . . cord-006870-f5w6fw6q 2172 1 Among among IN cord-006870-f5w6fw6q 2172 2 the the DT cord-006870-f5w6fw6q 2172 3 included include VBN cord-006870-f5w6fw6q 2172 4 patients patient NNS cord-006870-f5w6fw6q 2172 5 ( ( -LRB- cord-006870-f5w6fw6q 2172 6 age age NN cord-006870-f5w6fw6q 2172 7 , , , cord-006870-f5w6fw6q 2172 8 66.3 66.3 CD cord-006870-f5w6fw6q 2172 9 ; ; : cord-006870-f5w6fw6q 2172 10 and and CC cord-006870-f5w6fw6q 2172 11 male male NN cord-006870-f5w6fw6q 2172 12 , , , cord-006870-f5w6fw6q 2172 13 55.2 55.2 CD cord-006870-f5w6fw6q 2172 14 % % NN cord-006870-f5w6fw6q 2172 15 ) ) -RRB- cord-006870-f5w6fw6q 2172 16 , , , cord-006870-f5w6fw6q 2172 17 16 16 CD cord-006870-f5w6fw6q 2172 18 patients patient NNS cord-006870-f5w6fw6q 2172 19 ( ( -LRB- cord-006870-f5w6fw6q 2172 20 11.3 11.3 CD cord-006870-f5w6fw6q 2172 21 % % NN cord-006870-f5w6fw6q 2172 22 ) ) -RRB- cord-006870-f5w6fw6q 2172 23 developed develop VBD cord-006870-f5w6fw6q 2172 24 major major JJ cord-006870-f5w6fw6q 2172 25 HT HT NNP cord-006870-f5w6fw6q 2172 26 over over IN cord-006870-f5w6fw6q 2172 27 the the DT cord-006870-f5w6fw6q 2172 28 first first JJ cord-006870-f5w6fw6q 2172 29 24 24 CD cord-006870-f5w6fw6q 2172 30 hours hour NNS cord-006870-f5w6fw6q 2172 31 after after IN cord-006870-f5w6fw6q 2172 32 successful successful JJ cord-006870-f5w6fw6q 2172 33 recanalization recanalization NN cord-006870-f5w6fw6q 2172 34 . . . cord-006870-f5w6fw6q 2173 1 Systolic systolic JJ cord-006870-f5w6fw6q 2173 2 BP BP NNP cord-006870-f5w6fw6q 2173 3 max max NNP cord-006870-f5w6fw6q 2173 4 - - HYPH cord-006870-f5w6fw6q 2173 5 min min NNP cord-006870-f5w6fw6q 2173 6 was be VBD cord-006870-f5w6fw6q 2173 7 significantly significantly RB cord-006870-f5w6fw6q 2173 8 increased increase VBN cord-006870-f5w6fw6q 2173 9 in in IN cord-006870-f5w6fw6q 2173 10 patients patient NNS cord-006870-f5w6fw6q 2173 11 with with IN cord-006870-f5w6fw6q 2173 12 major major JJ cord-006870-f5w6fw6q 2173 13 HT ht NN cord-006870-f5w6fw6q 2173 14 compared compare VBN cord-006870-f5w6fw6q 2173 15 to to IN cord-006870-f5w6fw6q 2173 16 those those DT cord-006870-f5w6fw6q 2173 17 without without IN cord-006870-f5w6fw6q 2173 18 major major JJ cord-006870-f5w6fw6q 2173 19 HT HT NNP cord-006870-f5w6fw6q 2173 20 ( ( -LRB- cord-006870-f5w6fw6q 2173 21 61.2 61.2 CD cord-006870-f5w6fw6q 2173 22 mmHg mmHg NNS cord-006870-f5w6fw6q 2173 23 vs. vs. NN cord-006870-f5w6fw6q 2173 24 44.2 44.2 CD cord-006870-f5w6fw6q 2173 25 mmHg mmHg NNS cord-006870-f5w6fw6q 2173 26 , , , cord-006870-f5w6fw6q 2173 27 P p NN cord-006870-f5w6fw6q 2173 28 = = SYM cord-006870-f5w6fw6q 2173 29 0.034 0.034 CD cord-006870-f5w6fw6q 2173 30 ) ) -RRB- cord-006870-f5w6fw6q 2174 1 while while IN cord-006870-f5w6fw6q 2174 2 other other JJ cord-006870-f5w6fw6q 2174 3 BP BP NNP cord-006870-f5w6fw6q 2174 4 parameters parameter NNS cord-006870-f5w6fw6q 2174 5 were be VBD cord-006870-f5w6fw6q 2174 6 not not RB cord-006870-f5w6fw6q 2174 7 . . . cord-006870-f5w6fw6q 2175 1 In in IN cord-006870-f5w6fw6q 2175 2 addition addition NN cord-006870-f5w6fw6q 2175 3 , , , cord-006870-f5w6fw6q 2175 4 systolic systolic JJ cord-006870-f5w6fw6q 2175 5 BP BP NNP cord-006870-f5w6fw6q 2175 6 max max NNP cord-006870-f5w6fw6q 2175 7 - - HYPH cord-006870-f5w6fw6q 2175 8 min min NNP cord-006870-f5w6fw6q 2175 9 was be VBD cord-006870-f5w6fw6q 2175 10 significantly significantly RB cord-006870-f5w6fw6q 2175 11 associated associate VBN cord-006870-f5w6fw6q 2175 12 with with IN cord-006870-f5w6fw6q 2175 13 symptomatic symptomatic JJ cord-006870-f5w6fw6q 2175 14 HT ht NN cord-006870-f5w6fw6q 2175 15 ( ( -LRB- cord-006870-f5w6fw6q 2175 16 n=11 n=11 NNP cord-006870-f5w6fw6q 2175 17 , , , cord-006870-f5w6fw6q 2175 18 7.8 7.8 CD cord-006870-f5w6fw6q 2175 19 % % NN cord-006870-f5w6fw6q 2175 20 , , , cord-006870-f5w6fw6q 2175 21 P p NN cord-006870-f5w6fw6q 2175 22 = = SYM cord-006870-f5w6fw6q 2175 23 0.007 0.007 CD cord-006870-f5w6fw6q 2175 24 ) ) -RRB- cord-006870-f5w6fw6q 2175 25 . . . cord-006870-f5w6fw6q 2176 1 After after IN cord-006870-f5w6fw6q 2176 2 adjusting adjust VBG cord-006870-f5w6fw6q 2176 3 for for IN cord-006870-f5w6fw6q 2176 4 confounders confounder NNS cord-006870-f5w6fw6q 2176 5 , , , cord-006870-f5w6fw6q 2176 6 systolic systolic JJ cord-006870-f5w6fw6q 2176 7 BP BP NNP cord-006870-f5w6fw6q 2176 8 max max NNP cord-006870-f5w6fw6q 2176 9 - - HYPH cord-006870-f5w6fw6q 2176 10 min min NNP cord-006870-f5w6fw6q 2176 11 was be VBD cord-006870-f5w6fw6q 2176 12 independently independently RB cord-006870-f5w6fw6q 2176 13 associated associate VBN cord-006870-f5w6fw6q 2176 14 with with IN cord-006870-f5w6fw6q 2176 15 major major JJ cord-006870-f5w6fw6q 2176 16 HT HT NNP cord-006870-f5w6fw6q 2176 17 ( ( -LRB- cord-006870-f5w6fw6q 2176 18 Odds odd NNS cord-006870-f5w6fw6q 2176 19 ratio ratio NN cord-006870-f5w6fw6q 2176 20 , , , cord-006870-f5w6fw6q 2176 21 1.028 1.028 CD cord-006870-f5w6fw6q 2176 22 ; ; : cord-006870-f5w6fw6q 2176 23 95 95 CD cord-006870-f5w6fw6q 2176 24 % % NN cord-006870-f5w6fw6q 2176 25 confidence confidence NN cord-006870-f5w6fw6q 2176 26 interval interval NN cord-006870-f5w6fw6q 2176 27 , , , cord-006870-f5w6fw6q 2176 28 1.004 1.004 CD cord-006870-f5w6fw6q 2176 29 - - HYPH cord-006870-f5w6fw6q 2176 30 1.051 1.051 CD cord-006870-f5w6fw6q 2176 31 ) ) -RRB- cord-006870-f5w6fw6q 2176 32 . . . cord-006870-f5w6fw6q 2177 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2177 2 results result NNS cord-006870-f5w6fw6q 2177 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 2177 4 that that IN cord-006870-f5w6fw6q 2177 5 absolute absolute JJ cord-006870-f5w6fw6q 2177 6 change change NN cord-006870-f5w6fw6q 2177 7 of of IN cord-006870-f5w6fw6q 2177 8 systemic systemic JJ cord-006870-f5w6fw6q 2177 9 BP BP NNP cord-006870-f5w6fw6q 2177 10 over over IN cord-006870-f5w6fw6q 2177 11 the the DT cord-006870-f5w6fw6q 2177 12 first first JJ cord-006870-f5w6fw6q 2177 13 24 24 CD cord-006870-f5w6fw6q 2177 14 hours hour NNS cord-006870-f5w6fw6q 2177 15 was be VBD cord-006870-f5w6fw6q 2177 16 associated associate VBN cord-006870-f5w6fw6q 2177 17 with with IN cord-006870-f5w6fw6q 2177 18 major major JJ cord-006870-f5w6fw6q 2177 19 and and CC cord-006870-f5w6fw6q 2177 20 symptomatic symptomatic JJ cord-006870-f5w6fw6q 2177 21 HT ht NN cord-006870-f5w6fw6q 2177 22 after after IN cord-006870-f5w6fw6q 2177 23 successful successful JJ cord-006870-f5w6fw6q 2177 24 mechanical mechanical JJ cord-006870-f5w6fw6q 2177 25 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 2177 26 after after IN cord-006870-f5w6fw6q 2177 27 acute acute JJ cord-006870-f5w6fw6q 2177 28 ischemic ischemic JJ cord-006870-f5w6fw6q 2177 29 stroke stroke NN cord-006870-f5w6fw6q 2177 30 . . . cord-006870-f5w6fw6q 2178 1 This this DT cord-006870-f5w6fw6q 2178 2 suggests suggest VBZ cord-006870-f5w6fw6q 2178 3 that that IN cord-006870-f5w6fw6q 2178 4 maintaining maintain VBG cord-006870-f5w6fw6q 2178 5 stable stable JJ cord-006870-f5w6fw6q 2178 6 systolic systolic JJ cord-006870-f5w6fw6q 2178 7 BP BP NNP cord-006870-f5w6fw6q 2178 8 is be VBZ cord-006870-f5w6fw6q 2178 9 an an DT cord-006870-f5w6fw6q 2178 10 important important JJ cord-006870-f5w6fw6q 2178 11 factor factor NN cord-006870-f5w6fw6q 2178 12 in in IN cord-006870-f5w6fw6q 2178 13 possibly possibly RB cord-006870-f5w6fw6q 2178 14 preventing prevent VBG cord-006870-f5w6fw6q 2178 15 major major JJ cord-006870-f5w6fw6q 2178 16 HT ht NN cord-006870-f5w6fw6q 2178 17 after after IN cord-006870-f5w6fw6q 2178 18 successful successful JJ cord-006870-f5w6fw6q 2178 19 recanalization recanalization NN cord-006870-f5w6fw6q 2178 20 . . . cord-006870-f5w6fw6q 2179 1 The the DT cord-006870-f5w6fw6q 2179 2 benefits benefit NNS cord-006870-f5w6fw6q 2179 3 of of IN cord-006870-f5w6fw6q 2179 4 intravenous intravenous JJ cord-006870-f5w6fw6q 2179 5 tissue tissue NN cord-006870-f5w6fw6q 2179 6 - - HYPH cord-006870-f5w6fw6q 2179 7 plasminogen plasminogen NN cord-006870-f5w6fw6q 2179 8 activator activator NN cord-006870-f5w6fw6q 2179 9 in in IN cord-006870-f5w6fw6q 2179 10 acute acute JJ cord-006870-f5w6fw6q 2179 11 ischemic ischemic JJ cord-006870-f5w6fw6q 2179 12 stroke stroke NN cord-006870-f5w6fw6q 2179 13 are be VBP cord-006870-f5w6fw6q 2179 14 highly highly RB cord-006870-f5w6fw6q 2179 15 timedependent timedependent JJ cord-006870-f5w6fw6q 2179 16 . . . cord-006870-f5w6fw6q 2180 1 However however RB cord-006870-f5w6fw6q 2180 2 , , , cord-006870-f5w6fw6q 2180 3 there there EX cord-006870-f5w6fw6q 2180 4 are be VBP cord-006870-f5w6fw6q 2180 5 so so RB cord-006870-f5w6fw6q 2180 6 many many JJ cord-006870-f5w6fw6q 2180 7 cross cross JJ cord-006870-f5w6fw6q 2180 8 - - JJ cord-006870-f5w6fw6q 2180 9 departmental departmental JJ cord-006870-f5w6fw6q 2180 10 tasks task NNS cord-006870-f5w6fw6q 2180 11 to to IN cord-006870-f5w6fw6q 2180 12 eligible eligible JJ cord-006870-f5w6fw6q 2180 13 patent patent NN cord-006870-f5w6fw6q 2180 14 that that WDT cord-006870-f5w6fw6q 2180 15 many many JJ cord-006870-f5w6fw6q 2180 16 stroke stroke NN cord-006870-f5w6fw6q 2180 17 centers center NNS cord-006870-f5w6fw6q 2180 18 have have VBP cord-006870-f5w6fw6q 2180 19 difficulty difficulty NN cord-006870-f5w6fw6q 2180 20 achieving achieve VBG cord-006870-f5w6fw6q 2180 21 the the DT cord-006870-f5w6fw6q 2180 22 guideline guideline NN cord-006870-f5w6fw6q 2180 23 recommended recommend VBD cord-006870-f5w6fw6q 2180 24 1-hour 1-hour CD cord-006870-f5w6fw6q 2180 25 door door NN cord-006870-f5w6fw6q 2180 26 - - HYPH cord-006870-f5w6fw6q 2180 27 to to IN cord-006870-f5w6fw6q 2180 28 - - HYPH cord-006870-f5w6fw6q 2180 29 needle needle NN cord-006870-f5w6fw6q 2180 30 ( ( -LRB- cord-006870-f5w6fw6q 2180 31 DTN DTN NNP cord-006870-f5w6fw6q 2180 32 ) ) -RRB- cord-006870-f5w6fw6q 2180 33 time time NN cord-006870-f5w6fw6q 2180 34 . . . cord-006870-f5w6fw6q 2181 1 We -PRON- PRP cord-006870-f5w6fw6q 2181 2 have have VBP cord-006870-f5w6fw6q 2181 3 developed develop VBN cord-006870-f5w6fw6q 2181 4 web web NN cord-006870-f5w6fw6q 2181 5 based base VBN cord-006870-f5w6fw6q 2181 6 visual visual JJ cord-006870-f5w6fw6q 2181 7 task task NN cord-006870-f5w6fw6q 2181 8 management management NN cord-006870-f5w6fw6q 2181 9 system system NN cord-006870-f5w6fw6q 2181 10 called call VBN cord-006870-f5w6fw6q 2181 11 " " `` cord-006870-f5w6fw6q 2181 12 Task Task NNP cord-006870-f5w6fw6q 2181 13 Calc Calc NNP cord-006870-f5w6fw6q 2181 14 . . . cord-006870-f5w6fw6q 2182 1 Stroke stroke NN cord-006870-f5w6fw6q 2182 2 " " '' cord-006870-f5w6fw6q 2182 3 ( ( -LRB- cord-006870-f5w6fw6q 2182 4 TCS TCS NNP cord-006870-f5w6fw6q 2182 5 ) ) -RRB- cord-006870-f5w6fw6q 2182 6 by by IN cord-006870-f5w6fw6q 2182 7 using use VBG cord-006870-f5w6fw6q 2182 8 information information NN cord-006870-f5w6fw6q 2182 9 and and CC cord-006870-f5w6fw6q 2182 10 communication communication NN cord-006870-f5w6fw6q 2182 11 technology technology NN cord-006870-f5w6fw6q 2182 12 . . . cord-006870-f5w6fw6q 2183 1 Herein herein RB cord-006870-f5w6fw6q 2183 2 , , , cord-006870-f5w6fw6q 2183 3 we -PRON- PRP cord-006870-f5w6fw6q 2183 4 performed perform VBD cord-006870-f5w6fw6q 2183 5 a a DT cord-006870-f5w6fw6q 2183 6 trial trial NN cord-006870-f5w6fw6q 2183 7 installation installation NN cord-006870-f5w6fw6q 2183 8 and and CC cord-006870-f5w6fw6q 2183 9 preliminary preliminary JJ cord-006870-f5w6fw6q 2183 10 evaluation evaluation NN cord-006870-f5w6fw6q 2183 11 of of IN cord-006870-f5w6fw6q 2183 12 TCS TCS NNP cord-006870-f5w6fw6q 2183 13 . . . cord-006870-f5w6fw6q 2184 1 The the DT cord-006870-f5w6fw6q 2184 2 application application NN cord-006870-f5w6fw6q 2184 3 software software NN cord-006870-f5w6fw6q 2184 4 of of IN cord-006870-f5w6fw6q 2184 5 TCS TCS NNP cord-006870-f5w6fw6q 2184 6 was be VBD cord-006870-f5w6fw6q 2184 7 designed design VBN cord-006870-f5w6fw6q 2184 8 to to TO cord-006870-f5w6fw6q 2184 9 run run VB cord-006870-f5w6fw6q 2184 10 on on IN cord-006870-f5w6fw6q 2184 11 the the DT cord-006870-f5w6fw6q 2184 12 Google Google NNP cord-006870-f5w6fw6q 2184 13 Cloud Cloud NNP cord-006870-f5w6fw6q 2184 14 Platform Platform NNP cord-006870-f5w6fw6q 2184 15 . . . cord-006870-f5w6fw6q 2185 1 TCS TCS NNP cord-006870-f5w6fw6q 2185 2 alerts alert VBZ cord-006870-f5w6fw6q 2185 3 the the DT cord-006870-f5w6fw6q 2185 4 relevant relevant JJ cord-006870-f5w6fw6q 2185 5 hospital hospital NN cord-006870-f5w6fw6q 2185 6 staff staff NN cord-006870-f5w6fw6q 2185 7 to to IN cord-006870-f5w6fw6q 2185 8 the the DT cord-006870-f5w6fw6q 2185 9 patient patient NN cord-006870-f5w6fw6q 2185 10 's 's POS cord-006870-f5w6fw6q 2185 11 arrival arrival NN cord-006870-f5w6fw6q 2185 12 condition condition NN cord-006870-f5w6fw6q 2185 13 and and CC cord-006870-f5w6fw6q 2185 14 time time NN cord-006870-f5w6fw6q 2185 15 , , , cord-006870-f5w6fw6q 2185 16 and and CC cord-006870-f5w6fw6q 2185 17 displayed display VBD cord-006870-f5w6fw6q 2185 18 tasks task NNS cord-006870-f5w6fw6q 2185 19 to to TO cord-006870-f5w6fw6q 2185 20 be be VB cord-006870-f5w6fw6q 2185 21 performed perform VBN cord-006870-f5w6fw6q 2185 22 and and CC cord-006870-f5w6fw6q 2185 23 its -PRON- PRP$ cord-006870-f5w6fw6q 2185 24 treatment treatment NN cord-006870-f5w6fw6q 2185 25 status status NN cord-006870-f5w6fw6q 2185 26 by by IN cord-006870-f5w6fw6q 2185 27 changing change VBG cord-006870-f5w6fw6q 2185 28 color color NN cord-006870-f5w6fw6q 2185 29 in in IN cord-006870-f5w6fw6q 2185 30 real real JJ cord-006870-f5w6fw6q 2185 31 time time NN cord-006870-f5w6fw6q 2185 32 on on IN cord-006870-f5w6fw6q 2185 33 networked networked JJ cord-006870-f5w6fw6q 2185 34 wall wall NN cord-006870-f5w6fw6q 2185 35 - - HYPH cord-006870-f5w6fw6q 2185 36 mounted mount VBN cord-006870-f5w6fw6q 2185 37 smart smart JJ cord-006870-f5w6fw6q 2185 38 devices device NNS cord-006870-f5w6fw6q 2185 39 in in IN cord-006870-f5w6fw6q 2185 40 the the DT cord-006870-f5w6fw6q 2185 41 several several JJ cord-006870-f5w6fw6q 2185 42 relevant relevant JJ cord-006870-f5w6fw6q 2185 43 departments department NNS cord-006870-f5w6fw6q 2185 44 . . . cord-006870-f5w6fw6q 2186 1 We -PRON- PRP cord-006870-f5w6fw6q 2186 2 started start VBD cord-006870-f5w6fw6q 2186 3 a a DT cord-006870-f5w6fw6q 2186 4 trial trial NN cord-006870-f5w6fw6q 2186 5 installation installation NN cord-006870-f5w6fw6q 2186 6 of of IN cord-006870-f5w6fw6q 2186 7 TCS TCS NNP cord-006870-f5w6fw6q 2186 8 during during IN cord-006870-f5w6fw6q 2186 9 the the DT cord-006870-f5w6fw6q 2186 10 daytime daytime NN cord-006870-f5w6fw6q 2186 11 from from IN cord-006870-f5w6fw6q 2186 12 August August NNP cord-006870-f5w6fw6q 2186 13 2015 2015 CD cord-006870-f5w6fw6q 2186 14 . . . cord-006870-f5w6fw6q 2187 1 We -PRON- PRP cord-006870-f5w6fw6q 2187 2 compared compare VBD cord-006870-f5w6fw6q 2187 3 lead lead NN cord-006870-f5w6fw6q 2187 4 times time NNS cord-006870-f5w6fw6q 2187 5 before before IN cord-006870-f5w6fw6q 2187 6 ( ( -LRB- cord-006870-f5w6fw6q 2187 7 August August NNP cord-006870-f5w6fw6q 2187 8 2014 2014 CD cord-006870-f5w6fw6q 2187 9 to to IN cord-006870-f5w6fw6q 2187 10 July July NNP cord-006870-f5w6fw6q 2187 11 2015 2015 CD cord-006870-f5w6fw6q 2187 12 ) ) -RRB- cord-006870-f5w6fw6q 2187 13 and and CC cord-006870-f5w6fw6q 2187 14 after after IN cord-006870-f5w6fw6q 2187 15 ( ( -LRB- cord-006870-f5w6fw6q 2187 16 August August NNP cord-006870-f5w6fw6q 2187 17 2015 2015 CD cord-006870-f5w6fw6q 2187 18 to to IN cord-006870-f5w6fw6q 2187 19 July July NNP cord-006870-f5w6fw6q 2187 20 2016 2016 CD cord-006870-f5w6fw6q 2187 21 ) ) -RRB- cord-006870-f5w6fw6q 2188 1 trial trial NN cord-006870-f5w6fw6q 2188 2 installation installation NN cord-006870-f5w6fw6q 2188 3 of of IN cord-006870-f5w6fw6q 2188 4 TCS TCS NNP cord-006870-f5w6fw6q 2188 5 . . . cord-006870-f5w6fw6q 2189 1 Trial trial NN cord-006870-f5w6fw6q 2189 2 installation installation NN cord-006870-f5w6fw6q 2189 3 of of IN cord-006870-f5w6fw6q 2189 4 TCS TCS NNP cord-006870-f5w6fw6q 2189 5 in in IN cord-006870-f5w6fw6q 2189 6 our -PRON- PRP$ cord-006870-f5w6fw6q 2189 7 hospital hospital NN cord-006870-f5w6fw6q 2189 8 showed show VBD cord-006870-f5w6fw6q 2189 9 successful successful JJ cord-006870-f5w6fw6q 2189 10 information information NN cord-006870-f5w6fw6q 2189 11 sharing sharing NN cord-006870-f5w6fw6q 2189 12 . . . cord-006870-f5w6fw6q 2190 1 A a DT cord-006870-f5w6fw6q 2190 2 total total NN cord-006870-f5w6fw6q 2190 3 of of IN cord-006870-f5w6fw6q 2190 4 33 33 CD cord-006870-f5w6fw6q 2190 5 patients patient NNS cord-006870-f5w6fw6q 2190 6 included include VBN cord-006870-f5w6fw6q 2190 7 ( ( -LRB- cord-006870-f5w6fw6q 2190 8 pre pre VB cord-006870-f5w6fw6q 2190 9 : : : cord-006870-f5w6fw6q 2190 10 13 13 CD cord-006870-f5w6fw6q 2190 11 , , , cord-006870-f5w6fw6q 2190 12 post post NN cord-006870-f5w6fw6q 2190 13 : : : cord-006870-f5w6fw6q 2190 14 20 20 CD cord-006870-f5w6fw6q 2190 15 ) ) -RRB- cord-006870-f5w6fw6q 2190 16 . . . cord-006870-f5w6fw6q 2191 1 After after IN cord-006870-f5w6fw6q 2191 2 the the DT cord-006870-f5w6fw6q 2191 3 installation installation NN cord-006870-f5w6fw6q 2191 4 , , , cord-006870-f5w6fw6q 2191 5 significant significant JJ cord-006870-f5w6fw6q 2191 6 reductions reduction NNS cord-006870-f5w6fw6q 2191 7 occurred occur VBD cord-006870-f5w6fw6q 2191 8 in in IN cord-006870-f5w6fw6q 2191 9 the the DT cord-006870-f5w6fw6q 2191 10 median median JJ cord-006870-f5w6fw6q 2191 11 time time NN cord-006870-f5w6fw6q 2191 12 from from IN cord-006870-f5w6fw6q 2191 13 door door NN cord-006870-f5w6fw6q 2191 14 to to TO cord-006870-f5w6fw6q 2191 15 complete complete VB cord-006870-f5w6fw6q 2191 16 blood blood NN cord-006870-f5w6fw6q 2191 17 count count NN cord-006870-f5w6fw6q 2191 18 time time NN cord-006870-f5w6fw6q 2191 19 [ [ -LRB- cord-006870-f5w6fw6q 2191 20 26.6 26.6 CD cord-006870-f5w6fw6q 2191 21 vs. vs. CC cord-006870-f5w6fw6q 2191 22 17.5 17.5 CD cord-006870-f5w6fw6q 2191 23 min min NN cord-006870-f5w6fw6q 2191 24 , , , cord-006870-f5w6fw6q 2191 25 p p NN cord-006870-f5w6fw6q 2191 26 < < XX cord-006870-f5w6fw6q 2191 27 0.001 0.001 CD cord-006870-f5w6fw6q 2191 28 ] ] -RRB- cord-006870-f5w6fw6q 2191 29 and and CC cord-006870-f5w6fw6q 2191 30 a a DT cord-006870-f5w6fw6q 2191 31 trend trend NN cord-006870-f5w6fw6q 2191 32 toward toward IN cord-006870-f5w6fw6q 2191 33 a a DT cord-006870-f5w6fw6q 2191 34 reduction reduction NN cord-006870-f5w6fw6q 2191 35 from from IN cord-006870-f5w6fw6q 2191 36 door door NN cord-006870-f5w6fw6q 2191 37 to to IN cord-006870-f5w6fw6q 2191 38 needle needle NN cord-006870-f5w6fw6q 2191 39 time time NN cord-006870-f5w6fw6q 2191 40 [ [ -LRB- cord-006870-f5w6fw6q 2191 41 36.0 36.0 CD cord-006870-f5w6fw6q 2191 42 vs. vs. IN cord-006870-f5w6fw6q 2191 43 30.0 30.0 CD cord-006870-f5w6fw6q 2191 44 min min NNP cord-006870-f5w6fw6q 2191 45 , , , cord-006870-f5w6fw6q 2191 46 p p NN cord-006870-f5w6fw6q 2191 47 = = SYM cord-006870-f5w6fw6q 2191 48 0.175 0.175 CD cord-006870-f5w6fw6q 2191 49 ] ] -RRB- cord-006870-f5w6fw6q 2191 50 . . . cord-006870-f5w6fw6q 2192 1 TCS TCS NNP cord-006870-f5w6fw6q 2192 2 may may MD cord-006870-f5w6fw6q 2192 3 be be VB cord-006870-f5w6fw6q 2192 4 useful useful JJ cord-006870-f5w6fw6q 2192 5 tool tool NN cord-006870-f5w6fw6q 2192 6 to to TO cord-006870-f5w6fw6q 2192 7 reduce reduce VB cord-006870-f5w6fw6q 2192 8 the the DT cord-006870-f5w6fw6q 2192 9 lead lead NN cord-006870-f5w6fw6q 2192 10 times time NNS cord-006870-f5w6fw6q 2192 11 of of IN cord-006870-f5w6fw6q 2192 12 acute acute JJ cord-006870-f5w6fw6q 2192 13 stroke stroke NN cord-006870-f5w6fw6q 2192 14 patients patient NNS cord-006870-f5w6fw6q 2192 15 . . . cord-006870-f5w6fw6q 2193 1 TCS TCS NNP cord-006870-f5w6fw6q 2193 2 is be VBZ cord-006870-f5w6fw6q 2193 3 a a DT cord-006870-f5w6fw6q 2193 4 new new JJ cord-006870-f5w6fw6q 2193 5 approach approach NN cord-006870-f5w6fw6q 2193 6 that that WDT cord-006870-f5w6fw6q 2193 7 has have VBZ cord-006870-f5w6fw6q 2193 8 the the DT cord-006870-f5w6fw6q 2193 9 potential potential NN cord-006870-f5w6fw6q 2193 10 to to TO cord-006870-f5w6fw6q 2193 11 promote promote VB cord-006870-f5w6fw6q 2193 12 efficiency efficiency NN cord-006870-f5w6fw6q 2193 13 for for IN cord-006870-f5w6fw6q 2193 14 acute acute JJ cord-006870-f5w6fw6q 2193 15 stroke stroke NN cord-006870-f5w6fw6q 2193 16 care care NN cord-006870-f5w6fw6q 2193 17 . . . cord-006870-f5w6fw6q 2194 1 Prior prior JJ cord-006870-f5w6fw6q 2194 2 history history NN cord-006870-f5w6fw6q 2194 3 of of IN cord-006870-f5w6fw6q 2194 4 intracranial intracranial JJ cord-006870-f5w6fw6q 2194 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2194 6 ( ( -LRB- cord-006870-f5w6fw6q 2194 7 ICH ICH NNP cord-006870-f5w6fw6q 2194 8 ) ) -RRB- cord-006870-f5w6fw6q 2194 9 has have VBZ cord-006870-f5w6fw6q 2194 10 been be VBN cord-006870-f5w6fw6q 2194 11 considered consider VBN cord-006870-f5w6fw6q 2194 12 a a DT cord-006870-f5w6fw6q 2194 13 contraindication contraindication NN cord-006870-f5w6fw6q 2194 14 to to IN cord-006870-f5w6fw6q 2194 15 administration administration NN cord-006870-f5w6fw6q 2194 16 of of IN cord-006870-f5w6fw6q 2194 17 intravenous intravenous JJ cord-006870-f5w6fw6q 2194 18 recombinant recombinant JJ cord-006870-f5w6fw6q 2194 19 tissue tissue NN cord-006870-f5w6fw6q 2194 20 plasminogen plasminogen NN cord-006870-f5w6fw6q 2194 21 activator activator NN cord-006870-f5w6fw6q 2194 22 in in IN cord-006870-f5w6fw6q 2194 23 acute acute JJ cord-006870-f5w6fw6q 2194 24 ischemic ischemic JJ cord-006870-f5w6fw6q 2194 25 stroke stroke NN cord-006870-f5w6fw6q 2194 26 , , , cord-006870-f5w6fw6q 2194 27 per per IN cord-006870-f5w6fw6q 2194 28 the the DT cord-006870-f5w6fw6q 2194 29 original original JJ cord-006870-f5w6fw6q 2194 30 Activase Activase NNP cord-006870-f5w6fw6q 2194 31 FDA FDA NNP cord-006870-f5w6fw6q 2194 32 label label NN cord-006870-f5w6fw6q 2194 33 and and CC cord-006870-f5w6fw6q 2194 34 2013 2013 CD cord-006870-f5w6fw6q 2194 35 AHA AHA NNP cord-006870-f5w6fw6q 2194 36 / / SYM cord-006870-f5w6fw6q 2194 37 ASA ASA NNP cord-006870-f5w6fw6q 2194 38 guidelines guideline NNS cord-006870-f5w6fw6q 2194 39 . . . cord-006870-f5w6fw6q 2195 1 However however RB cord-006870-f5w6fw6q 2195 2 , , , cord-006870-f5w6fw6q 2195 3 limited limited JJ cord-006870-f5w6fw6q 2195 4 data datum NNS cord-006870-f5w6fw6q 2195 5 are be VBP cord-006870-f5w6fw6q 2195 6 available available JJ cord-006870-f5w6fw6q 2195 7 on on IN cord-006870-f5w6fw6q 2195 8 the the DT cord-006870-f5w6fw6q 2195 9 risks risk NNS cord-006870-f5w6fw6q 2195 10 of of IN cord-006870-f5w6fw6q 2195 11 lysis lysis NN cord-006870-f5w6fw6q 2195 12 in in IN cord-006870-f5w6fw6q 2195 13 patients patient NNS cord-006870-f5w6fw6q 2195 14 with with IN cord-006870-f5w6fw6q 2195 15 prior prior JJ cord-006870-f5w6fw6q 2195 16 ICH ICH NNP cord-006870-f5w6fw6q 2195 17 . . . cord-006870-f5w6fw6q 2196 1 We -PRON- PRP cord-006870-f5w6fw6q 2196 2 performed perform VBD cord-006870-f5w6fw6q 2196 3 a a DT cord-006870-f5w6fw6q 2196 4 cross cross JJ cord-006870-f5w6fw6q 2196 5 - - JJ cord-006870-f5w6fw6q 2196 6 sectional sectional JJ cord-006870-f5w6fw6q 2196 7 study study NN cord-006870-f5w6fw6q 2196 8 of of IN cord-006870-f5w6fw6q 2196 9 adult adult NN cord-006870-f5w6fw6q 2196 10 patients patient NNS cord-006870-f5w6fw6q 2196 11 who who WP cord-006870-f5w6fw6q 2196 12 received receive VBD cord-006870-f5w6fw6q 2196 13 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 2196 14 , , , cord-006870-f5w6fw6q 2196 15 using use VBG cord-006870-f5w6fw6q 2196 16 administrative administrative JJ cord-006870-f5w6fw6q 2196 17 claims claim NNS cord-006870-f5w6fw6q 2196 18 data datum NNS cord-006870-f5w6fw6q 2196 19 on on IN cord-006870-f5w6fw6q 2196 20 admissions admission NNS cord-006870-f5w6fw6q 2196 21 to to IN cord-006870-f5w6fw6q 2196 22 acute acute JJ cord-006870-f5w6fw6q 2196 23 care care NN cord-006870-f5w6fw6q 2196 24 hospitals hospital NNS cord-006870-f5w6fw6q 2196 25 in in IN cord-006870-f5w6fw6q 2196 26 California California NNP cord-006870-f5w6fw6q 2196 27 between between IN cord-006870-f5w6fw6q 2196 28 2005 2005 CD cord-006870-f5w6fw6q 2196 29 - - SYM cord-006870-f5w6fw6q 2196 30 2011 2011 CD cord-006870-f5w6fw6q 2196 31 . . . cord-006870-f5w6fw6q 2197 1 Diagnosis diagnosis NN cord-006870-f5w6fw6q 2197 2 codes code NNS cord-006870-f5w6fw6q 2197 3 were be VBD cord-006870-f5w6fw6q 2197 4 used use VBN cord-006870-f5w6fw6q 2197 5 to to TO cord-006870-f5w6fw6q 2197 6 identify identify VB cord-006870-f5w6fw6q 2197 7 patients patient NNS cord-006870-f5w6fw6q 2197 8 who who WP cord-006870-f5w6fw6q 2197 9 received receive VBD cord-006870-f5w6fw6q 2197 10 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 2197 11 , , , cord-006870-f5w6fw6q 2197 12 and and CC cord-006870-f5w6fw6q 2197 13 to to TO cord-006870-f5w6fw6q 2197 14 ascertain ascertain VB cord-006870-f5w6fw6q 2197 15 ( ( -LRB- cord-006870-f5w6fw6q 2197 16 1 1 LS cord-006870-f5w6fw6q 2197 17 ) ) -RRB- cord-006870-f5w6fw6q 2197 18 a a DT cord-006870-f5w6fw6q 2197 19 prior prior JJ cord-006870-f5w6fw6q 2197 20 diagnosis diagnosis NN cord-006870-f5w6fw6q 2197 21 of of IN cord-006870-f5w6fw6q 2197 22 ICH ICH NNP cord-006870-f5w6fw6q 2197 23 , , , cord-006870-f5w6fw6q 2197 24 including include VBG cord-006870-f5w6fw6q 2197 25 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 2197 26 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2197 27 ( ( -LRB- cord-006870-f5w6fw6q 2197 28 IPH IPH NNP cord-006870-f5w6fw6q 2197 29 ) ) -RRB- cord-006870-f5w6fw6q 2197 30 , , , cord-006870-f5w6fw6q 2197 31 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2197 32 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2197 33 ( ( -LRB- cord-006870-f5w6fw6q 2197 34 SAH SAH NNP cord-006870-f5w6fw6q 2197 35 ) ) -RRB- cord-006870-f5w6fw6q 2197 36 , , , cord-006870-f5w6fw6q 2197 37 subdural subdural JJ cord-006870-f5w6fw6q 2197 38 hematoma hematoma NN cord-006870-f5w6fw6q 2197 39 ( ( -LRB- cord-006870-f5w6fw6q 2197 40 SDH SDH NNP cord-006870-f5w6fw6q 2197 41 ) ) -RRB- cord-006870-f5w6fw6q 2197 42 , , , cord-006870-f5w6fw6q 2197 43 or or CC cord-006870-f5w6fw6q 2197 44 epidural epidural NN cord-006870-f5w6fw6q 2197 45 hematoma hematoma NN cord-006870-f5w6fw6q 2197 46 ( ( -LRB- cord-006870-f5w6fw6q 2197 47 EDH EDH NNP cord-006870-f5w6fw6q 2197 48 ) ) -RRB- cord-006870-f5w6fw6q 2197 49 ; ; : cord-006870-f5w6fw6q 2197 50 and and CC cord-006870-f5w6fw6q 2197 51 ( ( -LRB- cord-006870-f5w6fw6q 2197 52 2 2 LS cord-006870-f5w6fw6q 2197 53 ) ) -RRB- cord-006870-f5w6fw6q 2197 54 relevant relevant JJ cord-006870-f5w6fw6q 2197 55 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 2197 56 , , , cord-006870-f5w6fw6q 2197 57 including include VBG cord-006870-f5w6fw6q 2197 58 hypertension hypertension NN cord-006870-f5w6fw6q 2197 59 , , , cord-006870-f5w6fw6q 2197 60 smoking smoking NN cord-006870-f5w6fw6q 2197 61 , , , cord-006870-f5w6fw6q 2197 62 diabetes diabetes NN cord-006870-f5w6fw6q 2197 63 , , , cord-006870-f5w6fw6q 2197 64 heart heart NN cord-006870-f5w6fw6q 2197 65 failure failure NN cord-006870-f5w6fw6q 2197 66 , , , cord-006870-f5w6fw6q 2197 67 atrial atrial JJ cord-006870-f5w6fw6q 2197 68 fibrillation fibrillation NN cord-006870-f5w6fw6q 2197 69 , , , cord-006870-f5w6fw6q 2197 70 renal renal JJ cord-006870-f5w6fw6q 2197 71 disease disease NN cord-006870-f5w6fw6q 2197 72 , , , cord-006870-f5w6fw6q 2197 73 malignancy malignancy NN cord-006870-f5w6fw6q 2197 74 , , , cord-006870-f5w6fw6q 2197 75 and and CC cord-006870-f5w6fw6q 2197 76 demographic demographic JJ cord-006870-f5w6fw6q 2197 77 data datum NNS cord-006870-f5w6fw6q 2197 78 . . . cord-006870-f5w6fw6q 2198 1 We -PRON- PRP cord-006870-f5w6fw6q 2198 2 used use VBD cord-006870-f5w6fw6q 2198 3 univariable univariable JJ cord-006870-f5w6fw6q 2198 4 and and CC cord-006870-f5w6fw6q 2198 5 multivariable multivariable JJ cord-006870-f5w6fw6q 2198 6 logistic logistic JJ cord-006870-f5w6fw6q 2198 7 regression regression NN cord-006870-f5w6fw6q 2198 8 to to TO cord-006870-f5w6fw6q 2198 9 model model VB cord-006870-f5w6fw6q 2198 10 the the DT cord-006870-f5w6fw6q 2198 11 odds odd NNS cord-006870-f5w6fw6q 2198 12 of of IN cord-006870-f5w6fw6q 2198 13 in in IN cord-006870-f5w6fw6q 2198 14 - - HYPH cord-006870-f5w6fw6q 2198 15 hospital hospital NN cord-006870-f5w6fw6q 2198 16 mortality mortality NN cord-006870-f5w6fw6q 2198 17 as as IN cord-006870-f5w6fw6q 2198 18 a a DT cord-006870-f5w6fw6q 2198 19 function function NN cord-006870-f5w6fw6q 2198 20 of of IN cord-006870-f5w6fw6q 2198 21 prior prior JJ cord-006870-f5w6fw6q 2198 22 ICH ICH NNP cord-006870-f5w6fw6q 2198 23 , , , cord-006870-f5w6fw6q 2198 24 after after IN cord-006870-f5w6fw6q 2198 25 adjusting adjust VBG cord-006870-f5w6fw6q 2198 26 for for IN cord-006870-f5w6fw6q 2198 27 potential potential JJ cord-006870-f5w6fw6q 2198 28 confounders confounder NNS cord-006870-f5w6fw6q 2198 29 . . . cord-006870-f5w6fw6q 2199 1 60,142 60,142 CD cord-006870-f5w6fw6q 2199 2 patients patient NNS cord-006870-f5w6fw6q 2199 3 received receive VBD cord-006870-f5w6fw6q 2199 4 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 2199 5 during during IN cord-006870-f5w6fw6q 2199 6 the the DT cord-006870-f5w6fw6q 2199 7 study study NN cord-006870-f5w6fw6q 2199 8 period period NN cord-006870-f5w6fw6q 2199 9 ( ( -LRB- cord-006870-f5w6fw6q 2199 10 mean mean VB cord-006870-f5w6fw6q 2199 11 age age NN cord-006870-f5w6fw6q 2199 12 65 65 CD cord-006870-f5w6fw6q 2199 13 [ [ -LRB- cord-006870-f5w6fw6q 2199 14 SD SD NNP cord-006870-f5w6fw6q 2199 15 15 15 CD cord-006870-f5w6fw6q 2199 16 ] ] -RRB- cord-006870-f5w6fw6q 2199 17 , , , cord-006870-f5w6fw6q 2199 18 female female JJ cord-006870-f5w6fw6q 2199 19 count count NN cord-006870-f5w6fw6q 2200 1 26,613 26,613 CD cord-006870-f5w6fw6q 2200 2 [ [ -LRB- cord-006870-f5w6fw6q 2200 3 44 44 CD cord-006870-f5w6fw6q 2200 4 % % NN cord-006870-f5w6fw6q 2200 5 ] ] -RRB- cord-006870-f5w6fw6q 2200 6 ) ) -RRB- cord-006870-f5w6fw6q 2200 7 . . . cord-006870-f5w6fw6q 2201 1 Of of IN cord-006870-f5w6fw6q 2201 2 these these DT cord-006870-f5w6fw6q 2201 3 , , , cord-006870-f5w6fw6q 2201 4 824 824 CD cord-006870-f5w6fw6q 2201 5 patients patient NNS cord-006870-f5w6fw6q 2201 6 ( ( -LRB- cord-006870-f5w6fw6q 2201 7 1.4 1.4 CD cord-006870-f5w6fw6q 2201 8 % % NN cord-006870-f5w6fw6q 2201 9 ) ) -RRB- cord-006870-f5w6fw6q 2201 10 had have VBD cord-006870-f5w6fw6q 2201 11 a a DT cord-006870-f5w6fw6q 2201 12 documented document VBN cord-006870-f5w6fw6q 2201 13 diagnosis diagnosis NN cord-006870-f5w6fw6q 2201 14 of of IN cord-006870-f5w6fw6q 2201 15 prior prior JJ cord-006870-f5w6fw6q 2201 16 ICH ICH NNP cord-006870-f5w6fw6q 2201 17 on on IN cord-006870-f5w6fw6q 2201 18 admission admission NN cord-006870-f5w6fw6q 2201 19 . . . cord-006870-f5w6fw6q 2202 1 Inhospital Inhospital NNP cord-006870-f5w6fw6q 2202 2 mortality mortality NN cord-006870-f5w6fw6q 2202 3 was be VBD cord-006870-f5w6fw6q 2202 4 7 7 CD cord-006870-f5w6fw6q 2202 5 % % NN cord-006870-f5w6fw6q 2202 6 overall overall JJ cord-006870-f5w6fw6q 2202 7 , , , cord-006870-f5w6fw6q 2202 8 6.9 6.9 CD cord-006870-f5w6fw6q 2202 9 % % NN cord-006870-f5w6fw6q 2202 10 for for IN cord-006870-f5w6fw6q 2202 11 patients patient NNS cord-006870-f5w6fw6q 2202 12 without without IN cord-006870-f5w6fw6q 2202 13 prior prior JJ cord-006870-f5w6fw6q 2202 14 ICH ICH NNP cord-006870-f5w6fw6q 2202 15 , , , cord-006870-f5w6fw6q 2202 16 and and CC cord-006870-f5w6fw6q 2202 17 33.1 33.1 CD cord-006870-f5w6fw6q 2202 18 % % NN cord-006870-f5w6fw6q 2202 19 for for IN cord-006870-f5w6fw6q 2202 20 patients patient NNS cord-006870-f5w6fw6q 2202 21 with with IN cord-006870-f5w6fw6q 2202 22 prior prior JJ cord-006870-f5w6fw6q 2202 23 ICH ICH NNP cord-006870-f5w6fw6q 2202 24 . . . cord-006870-f5w6fw6q 2203 1 In in IN cord-006870-f5w6fw6q 2203 2 multivariable multivariable JJ cord-006870-f5w6fw6q 2203 3 analysis analysis NN cord-006870-f5w6fw6q 2203 4 , , , cord-006870-f5w6fw6q 2203 5 all all DT cord-006870-f5w6fw6q 2203 6 prior prior JJ cord-006870-f5w6fw6q 2203 7 ICH ICH NNP cord-006870-f5w6fw6q 2203 8 subtypes subtype NNS cord-006870-f5w6fw6q 2203 9 remained remain VBD cord-006870-f5w6fw6q 2203 10 independently independently RB cord-006870-f5w6fw6q 2203 11 associated associate VBN cord-006870-f5w6fw6q 2203 12 with with IN cord-006870-f5w6fw6q 2203 13 in in IN cord-006870-f5w6fw6q 2203 14 - - HYPH cord-006870-f5w6fw6q 2203 15 hospital hospital NN cord-006870-f5w6fw6q 2203 16 mortality mortality NN cord-006870-f5w6fw6q 2203 17 , , , cord-006870-f5w6fw6q 2203 18 including include VBG cord-006870-f5w6fw6q 2203 19 IPH IPH NNP cord-006870-f5w6fw6q 2203 20 ( ( -LRB- cord-006870-f5w6fw6q 2203 21 OR OR NNP cord-006870-f5w6fw6q 2203 22 5.9 5.9 CD cord-006870-f5w6fw6q 2203 23 , , , cord-006870-f5w6fw6q 2203 24 CI CI NNP cord-006870-f5w6fw6q 2203 25 4.9 4.9 CD cord-006870-f5w6fw6q 2203 26 - - HYPH cord-006870-f5w6fw6q 2203 27 7.1 7.1 CD cord-006870-f5w6fw6q 2203 28 , , , cord-006870-f5w6fw6q 2203 29 P p NN cord-006870-f5w6fw6q 2203 30 < < XX cord-006870-f5w6fw6q 2203 31 2e-16 2e-16 CD cord-006870-f5w6fw6q 2203 32 ) ) -RRB- cord-006870-f5w6fw6q 2203 33 ; ; : cord-006870-f5w6fw6q 2203 34 SAH SAH NNP cord-006870-f5w6fw6q 2203 35 ( ( -LRB- cord-006870-f5w6fw6q 2203 36 OR OR NNP cord-006870-f5w6fw6q 2203 37 6.5 6.5 CD cord-006870-f5w6fw6q 2203 38 , , , cord-006870-f5w6fw6q 2203 39 CI CI NNP cord-006870-f5w6fw6q 2203 40 4.8 4.8 CD cord-006870-f5w6fw6q 2203 41 - - HYPH cord-006870-f5w6fw6q 2203 42 8.8 8.8 CD cord-006870-f5w6fw6q 2203 43 , , , cord-006870-f5w6fw6q 2203 44 P p NN cord-006870-f5w6fw6q 2203 45 < < XX cord-006870-f5w6fw6q 2203 46 2e-16 2e-16 CD cord-006870-f5w6fw6q 2203 47 ) ) -RRB- cord-006870-f5w6fw6q 2203 48 ; ; : cord-006870-f5w6fw6q 2203 49 and and CC cord-006870-f5w6fw6q 2203 50 SDH SDH NNP cord-006870-f5w6fw6q 2203 51 ( ( -LRB- cord-006870-f5w6fw6q 2203 52 OR or CC cord-006870-f5w6fw6q 2203 53 3.8 3.8 CD cord-006870-f5w6fw6q 2203 54 , , , cord-006870-f5w6fw6q 2203 55 CI CI NNP cord-006870-f5w6fw6q 2203 56 1.8 1.8 CD cord-006870-f5w6fw6q 2203 57 - - HYPH cord-006870-f5w6fw6q 2203 58 7.5 7.5 CD cord-006870-f5w6fw6q 2203 59 , , , cord-006870-f5w6fw6q 2203 60 P=0.0002 P=0.0002 NNP cord-006870-f5w6fw6q 2203 61 ) ) -RRB- cord-006870-f5w6fw6q 2203 62 . . . cord-006870-f5w6fw6q 2204 1 Only only RB cord-006870-f5w6fw6q 2204 2 4 4 CD cord-006870-f5w6fw6q 2204 3 patients patient NNS cord-006870-f5w6fw6q 2204 4 had have VBD cord-006870-f5w6fw6q 2204 5 EDH EDH NNP cord-006870-f5w6fw6q 2204 6 and and CC cord-006870-f5w6fw6q 2204 7 testing testing NN cord-006870-f5w6fw6q 2204 8 was be VBD cord-006870-f5w6fw6q 2204 9 not not RB cord-006870-f5w6fw6q 2204 10 possible possible JJ cord-006870-f5w6fw6q 2204 11 . . . cord-006870-f5w6fw6q 2205 1 1.4 1.4 CD cord-006870-f5w6fw6q 2205 2 % % NN cord-006870-f5w6fw6q 2205 3 of of IN cord-006870-f5w6fw6q 2205 4 patients patient NNS cord-006870-f5w6fw6q 2205 5 who who WP cord-006870-f5w6fw6q 2205 6 received receive VBD cord-006870-f5w6fw6q 2205 7 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 2205 8 during during IN cord-006870-f5w6fw6q 2205 9 the the DT cord-006870-f5w6fw6q 2205 10 study study NN cord-006870-f5w6fw6q 2205 11 period period NN cord-006870-f5w6fw6q 2205 12 had have VBD cord-006870-f5w6fw6q 2205 13 prior prior JJ cord-006870-f5w6fw6q 2205 14 diagnosis diagnosis NN cord-006870-f5w6fw6q 2205 15 of of IN cord-006870-f5w6fw6q 2205 16 ICH ICH NNP cord-006870-f5w6fw6q 2205 17 . . . cord-006870-f5w6fw6q 2206 1 Prior prior RB cord-006870-f5w6fw6q 2206 2 ICH ICH NNP cord-006870-f5w6fw6q 2206 3 was be VBD cord-006870-f5w6fw6q 2206 4 found find VBN cord-006870-f5w6fw6q 2206 5 to to TO cord-006870-f5w6fw6q 2206 6 be be VB cord-006870-f5w6fw6q 2206 7 significantly significantly RB cord-006870-f5w6fw6q 2206 8 associated associate VBN cord-006870-f5w6fw6q 2206 9 with with IN cord-006870-f5w6fw6q 2206 10 in in IN cord-006870-f5w6fw6q 2206 11 - - HYPH cord-006870-f5w6fw6q 2206 12 hospital hospital NN cord-006870-f5w6fw6q 2206 13 mortality mortality NN cord-006870-f5w6fw6q 2206 14 regardless regardless RB cord-006870-f5w6fw6q 2206 15 of of IN cord-006870-f5w6fw6q 2206 16 ICH ICH NNP cord-006870-f5w6fw6q 2206 17 subtype subtype NN cord-006870-f5w6fw6q 2206 18 . . . cord-006870-f5w6fw6q 2207 1 We -PRON- PRP cord-006870-f5w6fw6q 2207 2 evaluated evaluate VBD cord-006870-f5w6fw6q 2207 3 the the DT cord-006870-f5w6fw6q 2207 4 association association NN cord-006870-f5w6fw6q 2207 5 between between IN cord-006870-f5w6fw6q 2207 6 early early JJ cord-006870-f5w6fw6q 2207 7 neurological neurological JJ cord-006870-f5w6fw6q 2207 8 improvement improvement NN cord-006870-f5w6fw6q 2207 9 ( ( -LRB- cord-006870-f5w6fw6q 2207 10 ENI ENI NNP cord-006870-f5w6fw6q 2207 11 ) ) -RRB- cord-006870-f5w6fw6q 2207 12 after after IN cord-006870-f5w6fw6q 2207 13 ERT ERT NNP cord-006870-f5w6fw6q 2207 14 and and CC cord-006870-f5w6fw6q 2207 15 time time NN cord-006870-f5w6fw6q 2207 16 spent spend VBN cord-006870-f5w6fw6q 2207 17 from from IN cord-006870-f5w6fw6q 2207 18 symptom symptom NN cord-006870-f5w6fw6q 2207 19 onset onset NN cord-006870-f5w6fw6q 2207 20 to to IN cord-006870-f5w6fw6q 2207 21 recanalization recanalization NN cord-006870-f5w6fw6q 2207 22 , , , cord-006870-f5w6fw6q 2207 23 according accord VBG cord-006870-f5w6fw6q 2207 24 to to IN cord-006870-f5w6fw6q 2207 25 the the DT cord-006870-f5w6fw6q 2207 26 degree degree NN cord-006870-f5w6fw6q 2207 27 of of IN cord-006870-f5w6fw6q 2207 28 collateral collateral JJ cord-006870-f5w6fw6q 2207 29 circulation circulation NN cord-006870-f5w6fw6q 2207 30 measured measure VBN cord-006870-f5w6fw6q 2207 31 using use VBG cord-006870-f5w6fw6q 2207 32 multiphase multiphase NN cord-006870-f5w6fw6q 2207 33 CTA CTA NNP cord-006870-f5w6fw6q 2207 34 . . . cord-006870-f5w6fw6q 2208 1 Patients patient NNS cord-006870-f5w6fw6q 2208 2 with with IN cord-006870-f5w6fw6q 2208 3 anterior anterior JJ cord-006870-f5w6fw6q 2208 4 circulation circulation NN cord-006870-f5w6fw6q 2208 5 occlusion occlusion NN cord-006870-f5w6fw6q 2208 6 who who WP cord-006870-f5w6fw6q 2208 7 underwent undergo VBD cord-006870-f5w6fw6q 2208 8 ERT ERT NNP cord-006870-f5w6fw6q 2208 9 based base VBN cord-006870-f5w6fw6q 2208 10 on on IN cord-006870-f5w6fw6q 2208 11 a a DT cord-006870-f5w6fw6q 2208 12 non non JJ cord-006870-f5w6fw6q 2208 13 - - JJ cord-006870-f5w6fw6q 2208 14 contrast contrast JJ cord-006870-f5w6fw6q 2208 15 brain brain NN cord-006870-f5w6fw6q 2208 16 CT CT NNP cord-006870-f5w6fw6q 2208 17 and and CC cord-006870-f5w6fw6q 2208 18 multiphase multiphase NN cord-006870-f5w6fw6q 2208 19 CTA CTA NNP cord-006870-f5w6fw6q 2208 20 were be VBD cord-006870-f5w6fw6q 2208 21 evaluated evaluate VBN cord-006870-f5w6fw6q 2208 22 . . . cord-006870-f5w6fw6q 2209 1 Collateral collateral NN cord-006870-f5w6fw6q 2209 2 status status NN cord-006870-f5w6fw6q 2209 3 was be VBD cord-006870-f5w6fw6q 2209 4 evaluated evaluate VBN cord-006870-f5w6fw6q 2209 5 using use VBG cord-006870-f5w6fw6q 2209 6 a a DT cord-006870-f5w6fw6q 2209 7 pial pial JJ cord-006870-f5w6fw6q 2209 8 arterial arterial NN cord-006870-f5w6fw6q 2209 9 filling filling NN cord-006870-f5w6fw6q 2209 10 score score NN cord-006870-f5w6fw6q 2209 11 , , , cord-006870-f5w6fw6q 2209 12 which which WDT cord-006870-f5w6fw6q 2209 13 was be VBD cord-006870-f5w6fw6q 2209 14 developed develop VBN cord-006870-f5w6fw6q 2209 15 into into IN cord-006870-f5w6fw6q 2209 16 a a DT cord-006870-f5w6fw6q 2209 17 six six CD cord-006870-f5w6fw6q 2209 18 - - HYPH cord-006870-f5w6fw6q 2209 19 point point NN cord-006870-f5w6fw6q 2209 20 scale scale NN cord-006870-f5w6fw6q 2209 21 . . . cord-006870-f5w6fw6q 2210 1 ENI ENI NNP cord-006870-f5w6fw6q 2210 2 was be VBD cord-006870-f5w6fw6q 2210 3 defined define VBN cord-006870-f5w6fw6q 2210 4 as as IN cord-006870-f5w6fw6q 2210 5 equal equal JJ cord-006870-f5w6fw6q 2210 6 to to IN cord-006870-f5w6fw6q 2210 7 more more JJR cord-006870-f5w6fw6q 2210 8 than than IN cord-006870-f5w6fw6q 2210 9 50 50 CD cord-006870-f5w6fw6q 2210 10 % % NN cord-006870-f5w6fw6q 2210 11 , , , cord-006870-f5w6fw6q 2210 12 or or CC cord-006870-f5w6fw6q 2210 13 as as IN cord-006870-f5w6fw6q 2210 14 an an DT cord-006870-f5w6fw6q 2210 15 8-point 8-point CD cord-006870-f5w6fw6q 2210 16 decrement decrement NN cord-006870-f5w6fw6q 2210 17 in in IN cord-006870-f5w6fw6q 2210 18 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2210 19 from from IN cord-006870-f5w6fw6q 2210 20 baseline baseline NN cord-006870-f5w6fw6q 2210 21 . . . cord-006870-f5w6fw6q 2211 1 Neurological neurological JJ cord-006870-f5w6fw6q 2211 2 statuses status NNS cord-006870-f5w6fw6q 2211 3 at at IN cord-006870-f5w6fw6q 2211 4 day day NN cord-006870-f5w6fw6q 2211 5 1 1 CD cord-006870-f5w6fw6q 2211 6 and and CC cord-006870-f5w6fw6q 2211 7 at at IN cord-006870-f5w6fw6q 2211 8 day day NN cord-006870-f5w6fw6q 2211 9 7 7 CD cord-006870-f5w6fw6q 2211 10 ( ( -LRB- cord-006870-f5w6fw6q 2211 11 or or CC cord-006870-f5w6fw6q 2211 12 discharge discharge NN cord-006870-f5w6fw6q 2211 13 ) ) -RRB- cord-006870-f5w6fw6q 2211 14 were be VBD cord-006870-f5w6fw6q 2211 15 determined determine VBN cord-006870-f5w6fw6q 2211 16 by by IN cord-006870-f5w6fw6q 2211 17 a a DT cord-006870-f5w6fw6q 2211 18 certified certify VBN cord-006870-f5w6fw6q 2211 19 neurologist neurologist NN cord-006870-f5w6fw6q 2211 20 using use VBG cord-006870-f5w6fw6q 2211 21 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2211 22 . . . cord-006870-f5w6fw6q 2212 1 The the DT cord-006870-f5w6fw6q 2212 2 collateral collateral JJ cord-006870-f5w6fw6q 2212 3 circulation circulation NN cord-006870-f5w6fw6q 2212 4 degree degree NN cord-006870-f5w6fw6q 2212 5 measured measure VBN cord-006870-f5w6fw6q 2212 6 by by IN cord-006870-f5w6fw6q 2212 7 multiphase multiphase NN cord-006870-f5w6fw6q 2212 8 CTA CTA NNP cord-006870-f5w6fw6q 2212 9 was be VBD cord-006870-f5w6fw6q 2212 10 inversely inversely RB cord-006870-f5w6fw6q 2212 11 correlated correlate VBN cord-006870-f5w6fw6q 2212 12 with with IN cord-006870-f5w6fw6q 2212 13 baseline baseline JJ cord-006870-f5w6fw6q 2212 14 stroke stroke NN cord-006870-f5w6fw6q 2212 15 severity severity NN cord-006870-f5w6fw6q 2212 16 ( ( -LRB- cord-006870-f5w6fw6q 2212 17 p=0.02 p=0.02 NN cord-006870-f5w6fw6q 2212 18 ) ) -RRB- cord-006870-f5w6fw6q 2212 19 . . . cord-006870-f5w6fw6q 2213 1 The the DT cord-006870-f5w6fw6q 2213 2 proportion proportion NN cord-006870-f5w6fw6q 2213 3 of of IN cord-006870-f5w6fw6q 2213 4 ENI ENI NNP cord-006870-f5w6fw6q 2213 5 at at IN cord-006870-f5w6fw6q 2213 6 day day NN cord-006870-f5w6fw6q 2213 7 1 1 CD cord-006870-f5w6fw6q 2213 8 was be VBD cord-006870-f5w6fw6q 2213 9 significantly significantly RB cord-006870-f5w6fw6q 2213 10 lower low JJR cord-006870-f5w6fw6q 2213 11 in in IN cord-006870-f5w6fw6q 2213 12 patients patient NNS cord-006870-f5w6fw6q 2213 13 with with IN cord-006870-f5w6fw6q 2213 14 poor poor JJ cord-006870-f5w6fw6q 2213 15 collateral collateral JJ cord-006870-f5w6fw6q 2213 16 status status NN cord-006870-f5w6fw6q 2213 17 ( ( -LRB- cord-006870-f5w6fw6q 2213 18 score score NN cord-006870-f5w6fw6q 2213 19 0~4 0~4 CD cord-006870-f5w6fw6q 2213 20 ) ) -RRB- cord-006870-f5w6fw6q 2213 21 according accord VBG cord-006870-f5w6fw6q 2213 22 to to IN cord-006870-f5w6fw6q 2213 23 the the DT cord-006870-f5w6fw6q 2213 24 time time NN cord-006870-f5w6fw6q 2213 25 from from IN cord-006870-f5w6fw6q 2213 26 symptom symptom NN cord-006870-f5w6fw6q 2213 27 onset onset NN cord-006870-f5w6fw6q 2213 28 to to IN cord-006870-f5w6fw6q 2213 29 recanalization recanalization NN cord-006870-f5w6fw6q 2213 30 ( ( -LRB- cord-006870-f5w6fw6q 2213 31 0 0 CD cord-006870-f5w6fw6q 2213 32 - - SYM cord-006870-f5w6fw6q 2213 33 180 180 CD cord-006870-f5w6fw6q 2213 34 , , , cord-006870-f5w6fw6q 2213 35 50.0 50.0 CD cord-006870-f5w6fw6q 2213 36 % % NN cord-006870-f5w6fw6q 2213 37 ; ; : cord-006870-f5w6fw6q 2213 38 180 180 CD cord-006870-f5w6fw6q 2213 39 - - SYM cord-006870-f5w6fw6q 2213 40 360 360 CD cord-006870-f5w6fw6q 2213 41 , , , cord-006870-f5w6fw6q 2213 42 14.8 14.8 CD cord-006870-f5w6fw6q 2213 43 % % NN cord-006870-f5w6fw6q 2213 44 ; ; : cord-006870-f5w6fw6q 2213 45 > > XX cord-006870-f5w6fw6q 2213 46 360 360 CD cord-006870-f5w6fw6q 2213 47 , , , cord-006870-f5w6fw6q 2213 48 14.3 14.3 CD cord-006870-f5w6fw6q 2213 49 % % NN cord-006870-f5w6fw6q 2213 50 ; ; : cord-006870-f5w6fw6q 2213 51 p=0.02 p=0.02 NNP cord-006870-f5w6fw6q 2213 52 ) ) -RRB- cord-006870-f5w6fw6q 2213 53 . . . cord-006870-f5w6fw6q 2214 1 However however RB cord-006870-f5w6fw6q 2214 2 , , , cord-006870-f5w6fw6q 2214 3 the the DT cord-006870-f5w6fw6q 2214 4 proportion proportion NN cord-006870-f5w6fw6q 2214 5 was be VBD cord-006870-f5w6fw6q 2214 6 similar similar JJ cord-006870-f5w6fw6q 2214 7 in in IN cord-006870-f5w6fw6q 2214 8 patients patient NNS cord-006870-f5w6fw6q 2214 9 with with IN cord-006870-f5w6fw6q 2214 10 a a DT cord-006870-f5w6fw6q 2214 11 good good JJ cord-006870-f5w6fw6q 2214 12 -180 -180 NN cord-006870-f5w6fw6q 2214 13 , , , cord-006870-f5w6fw6q 2214 14 57.1 57.1 CD cord-006870-f5w6fw6q 2214 15 % % NN cord-006870-f5w6fw6q 2214 16 ; ; : cord-006870-f5w6fw6q 2214 17 180 180 CD cord-006870-f5w6fw6q 2214 18 - - SYM cord-006870-f5w6fw6q 2214 19 360 360 CD cord-006870-f5w6fw6q 2214 20 , , , cord-006870-f5w6fw6q 2214 21 50.0 50.0 CD cord-006870-f5w6fw6q 2214 22 % % NN cord-006870-f5w6fw6q 2214 23 ; ; : cord-006870-f5w6fw6q 2214 24 360 360 CD cord-006870-f5w6fw6q 2214 25 - - HYPH cord-006870-f5w6fw6q 2214 26 480 480 CD cord-006870-f5w6fw6q 2214 27 , , , cord-006870-f5w6fw6q 2214 28 50.0 50.0 CD cord-006870-f5w6fw6q 2214 29 % % NN cord-006870-f5w6fw6q 2214 30 ; ; : cord-006870-f5w6fw6q 2214 31 > > XX cord-006870-f5w6fw6q 2214 32 480 480 CD cord-006870-f5w6fw6q 2214 33 , , , cord-006870-f5w6fw6q 2214 34 50.0 50.0 CD cord-006870-f5w6fw6q 2214 35 % % NN cord-006870-f5w6fw6q 2214 36 ; ; : cord-006870-f5w6fw6q 2214 37 p=0.97 p=0.97 NNP cord-006870-f5w6fw6q 2214 38 , , , cord-006870-f5w6fw6q 2214 39 day day NN cord-006870-f5w6fw6q 2214 40 7 7 CD cord-006870-f5w6fw6q 2214 41 or or CC cord-006870-f5w6fw6q 2214 42 discharge discharge NN cord-006870-f5w6fw6q 2214 43 ; ; : cord-006870-f5w6fw6q 2214 44 0 0 CD cord-006870-f5w6fw6q 2214 45 - - SYM cord-006870-f5w6fw6q 2214 46 180 180 CD cord-006870-f5w6fw6q 2214 47 , , , cord-006870-f5w6fw6q 2214 48 81.0 81.0 CD cord-006870-f5w6fw6q 2214 49 % % NN cord-006870-f5w6fw6q 2214 50 ; ; : cord-006870-f5w6fw6q 2214 51 180 180 CD cord-006870-f5w6fw6q 2214 52 - - SYM cord-006870-f5w6fw6q 2214 53 360 360 CD cord-006870-f5w6fw6q 2214 54 , , , cord-006870-f5w6fw6q 2214 55 71.4 71.4 CD cord-006870-f5w6fw6q 2214 56 % % NN cord-006870-f5w6fw6q 2214 57 ; ; : cord-006870-f5w6fw6q 2214 58 360 360 CD cord-006870-f5w6fw6q 2214 59 - - HYPH cord-006870-f5w6fw6q 2214 60 480 480 CD cord-006870-f5w6fw6q 2214 61 , , , cord-006870-f5w6fw6q 2214 62 100.0 100.0 CD cord-006870-f5w6fw6q 2214 63 % % NN cord-006870-f5w6fw6q 2214 64 ; ; : cord-006870-f5w6fw6q 2214 65 > > XX cord-006870-f5w6fw6q 2214 66 480 480 CD cord-006870-f5w6fw6q 2214 67 , , , cord-006870-f5w6fw6q 2214 68 66.7 66.7 CD cord-006870-f5w6fw6q 2214 69 % % NN cord-006870-f5w6fw6q 2214 70 ; ; : cord-006870-f5w6fw6q 2214 71 p=0.68 p=0.68 NN cord-006870-f5w6fw6q 2214 72 ) ) -RRB- cord-006870-f5w6fw6q 2214 73 . . . cord-006870-f5w6fw6q 2215 1 Collateral collateral NN cord-006870-f5w6fw6q 2215 2 status status NN cord-006870-f5w6fw6q 2215 3 was be VBD cord-006870-f5w6fw6q 2215 4 the the DT cord-006870-f5w6fw6q 2215 5 best good JJS cord-006870-f5w6fw6q 2215 6 predictor predictor NN cord-006870-f5w6fw6q 2215 7 for for IN cord-006870-f5w6fw6q 2215 8 ENI ENI NNP cord-006870-f5w6fw6q 2215 9 after after IN cord-006870-f5w6fw6q 2215 10 ERT ERT NNP cord-006870-f5w6fw6q 2215 11 . . . cord-006870-f5w6fw6q 2216 1 ENI ENI NNP cord-006870-f5w6fw6q 2216 2 was be VBD cord-006870-f5w6fw6q 2216 3 achieved achieve VBN cord-006870-f5w6fw6q 2216 4 in in IN cord-006870-f5w6fw6q 2216 5 only only RB cord-006870-f5w6fw6q 2216 6 5 5 CD cord-006870-f5w6fw6q 2216 7 ( ( -LRB- cord-006870-f5w6fw6q 2216 8 14.3 14.3 CD cord-006870-f5w6fw6q 2216 9 % % NN cord-006870-f5w6fw6q 2216 10 ) ) -RRB- cord-006870-f5w6fw6q 2216 11 patients patient NNS cord-006870-f5w6fw6q 2216 12 with with IN cord-006870-f5w6fw6q 2216 13 poor poor JJ cord-006870-f5w6fw6q 2216 14 collateral collateral JJ cord-006870-f5w6fw6q 2216 15 status status NN cord-006870-f5w6fw6q 2216 16 , , , cord-006870-f5w6fw6q 2216 17 and and CC cord-006870-f5w6fw6q 2216 18 their -PRON- PRP$ cord-006870-f5w6fw6q 2216 19 time time NN cord-006870-f5w6fw6q 2216 20 from from IN cord-006870-f5w6fw6q 2216 21 symptom symptom NN cord-006870-f5w6fw6q 2216 22 onset onset NN cord-006870-f5w6fw6q 2216 23 to to IN cord-006870-f5w6fw6q 2216 24 recanalization recanalization NN cord-006870-f5w6fw6q 2216 25 was be VBD cord-006870-f5w6fw6q 2216 26 more more JJR cord-006870-f5w6fw6q 2216 27 than than IN cord-006870-f5w6fw6q 2216 28 180 180 CD cord-006870-f5w6fw6q 2216 29 minutes minute NNS cord-006870-f5w6fw6q 2216 30 . . . cord-006870-f5w6fw6q 2217 1 The the DT cord-006870-f5w6fw6q 2217 2 time time NN cord-006870-f5w6fw6q 2217 3 window window NN cord-006870-f5w6fw6q 2217 4 for for IN cord-006870-f5w6fw6q 2217 5 ERT ERT NNP cord-006870-f5w6fw6q 2217 6 might may MD cord-006870-f5w6fw6q 2217 7 differ differ VB cord-006870-f5w6fw6q 2217 8 according accord VBG cord-006870-f5w6fw6q 2217 9 to to IN cord-006870-f5w6fw6q 2217 10 baseline baseline JJ cord-006870-f5w6fw6q 2217 11 collateral collateral JJ cord-006870-f5w6fw6q 2217 12 status status NN cord-006870-f5w6fw6q 2217 13 measured measure VBN cord-006870-f5w6fw6q 2217 14 by by IN cord-006870-f5w6fw6q 2217 15 multiphase multiphase NN cord-006870-f5w6fw6q 2217 16 CTA CTA NNP cord-006870-f5w6fw6q 2217 17 . . . cord-006870-f5w6fw6q 2218 1 The the DT cord-006870-f5w6fw6q 2218 2 current current JJ cord-006870-f5w6fw6q 2218 3 time time NN cord-006870-f5w6fw6q 2218 4 window window NN cord-006870-f5w6fw6q 2218 5 for for IN cord-006870-f5w6fw6q 2218 6 ERT ERT NNP cord-006870-f5w6fw6q 2218 7 within within IN cord-006870-f5w6fw6q 2218 8 6 6 CD cord-006870-f5w6fw6q 2218 9 hours hour NNS cord-006870-f5w6fw6q 2218 10 from from IN cord-006870-f5w6fw6q 2218 11 symptom symptom NN cord-006870-f5w6fw6q 2218 12 onset onset NN cord-006870-f5w6fw6q 2218 13 to to IN cord-006870-f5w6fw6q 2218 14 groin groin NN cord-006870-f5w6fw6q 2218 15 puncture puncture NN cord-006870-f5w6fw6q 2218 16 could could MD cord-006870-f5w6fw6q 2218 17 be be VB cord-006870-f5w6fw6q 2218 18 Atrial atrial JJ cord-006870-f5w6fw6q 2218 19 fibrillation fibrillation NN cord-006870-f5w6fw6q 2218 20 ( ( -LRB- cord-006870-f5w6fw6q 2218 21 AF AF NNP cord-006870-f5w6fw6q 2218 22 ) ) -RRB- cord-006870-f5w6fw6q 2218 23 is be VBZ cord-006870-f5w6fw6q 2218 24 the the DT cord-006870-f5w6fw6q 2218 25 most most RBS cord-006870-f5w6fw6q 2218 26 common common JJ cord-006870-f5w6fw6q 2218 27 cardiac cardiac JJ cord-006870-f5w6fw6q 2218 28 arrhythmia arrhythmia NN cord-006870-f5w6fw6q 2218 29 among among IN cord-006870-f5w6fw6q 2218 30 adults adult NNS cord-006870-f5w6fw6q 2218 31 . . . cord-006870-f5w6fw6q 2219 1 Despite despite IN cord-006870-f5w6fw6q 2219 2 of of IN cord-006870-f5w6fw6q 2219 3 the the DT cord-006870-f5w6fw6q 2219 4 proven prove VBN cord-006870-f5w6fw6q 2219 5 advantage advantage NN cord-006870-f5w6fw6q 2219 6 in in IN cord-006870-f5w6fw6q 2219 7 primary primary JJ cord-006870-f5w6fw6q 2219 8 and and CC cord-006870-f5w6fw6q 2219 9 secondary secondary JJ cord-006870-f5w6fw6q 2219 10 stroke stroke NN cord-006870-f5w6fw6q 2219 11 prevention prevention NN cord-006870-f5w6fw6q 2219 12 in in IN cord-006870-f5w6fw6q 2219 13 patients patient NNS cord-006870-f5w6fw6q 2219 14 with with IN cord-006870-f5w6fw6q 2219 15 AF AF NNP cord-006870-f5w6fw6q 2219 16 , , , cord-006870-f5w6fw6q 2219 17 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 2219 18 therapy therapy NN cord-006870-f5w6fw6q 2219 19 has have VBZ cord-006870-f5w6fw6q 2219 20 been be VBN cord-006870-f5w6fw6q 2219 21 reported report VBN cord-006870-f5w6fw6q 2219 22 to to TO cord-006870-f5w6fw6q 2219 23 be be VB cord-006870-f5w6fw6q 2219 24 still still RB cord-006870-f5w6fw6q 2219 25 underused underused JJ cord-006870-f5w6fw6q 2219 26 in in IN cord-006870-f5w6fw6q 2219 27 many many JJ cord-006870-f5w6fw6q 2219 28 countries country NNS cord-006870-f5w6fw6q 2219 29 . . . cord-006870-f5w6fw6q 2220 1 However however RB cord-006870-f5w6fw6q 2220 2 , , , cord-006870-f5w6fw6q 2220 3 there there EX cord-006870-f5w6fw6q 2220 4 is be VBZ cord-006870-f5w6fw6q 2220 5 a a DT cord-006870-f5w6fw6q 2220 6 little little JJ cord-006870-f5w6fw6q 2220 7 data datum NNS cord-006870-f5w6fw6q 2220 8 about about IN cord-006870-f5w6fw6q 2220 9 the the DT cord-006870-f5w6fw6q 2220 10 incidence incidence NN cord-006870-f5w6fw6q 2220 11 of of IN cord-006870-f5w6fw6q 2220 12 AF AF NNP cord-006870-f5w6fw6q 2220 13 and and CC cord-006870-f5w6fw6q 2220 14 any any DT cord-006870-f5w6fw6q 2220 15 changing change VBG cord-006870-f5w6fw6q 2220 16 pattern pattern NN cord-006870-f5w6fw6q 2220 17 of of IN cord-006870-f5w6fw6q 2220 18 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 2220 19 therapy therapy NN cord-006870-f5w6fw6q 2220 20 among among IN cord-006870-f5w6fw6q 2220 21 patients patient NNS cord-006870-f5w6fw6q 2220 22 with with IN cord-006870-f5w6fw6q 2220 23 AF AF NNP cord-006870-f5w6fw6q 2220 24 over over IN cord-006870-f5w6fw6q 2220 25 the the DT cord-006870-f5w6fw6q 2220 26 past past JJ cord-006870-f5w6fw6q 2220 27 decade decade NN cord-006870-f5w6fw6q 2220 28 in in IN cord-006870-f5w6fw6q 2220 29 Korea Korea NNP cord-006870-f5w6fw6q 2220 30 . . . cord-006870-f5w6fw6q 2221 1 Data datum NNS cord-006870-f5w6fw6q 2221 2 source source NN cord-006870-f5w6fw6q 2221 3 for for IN cord-006870-f5w6fw6q 2221 4 this this DT cord-006870-f5w6fw6q 2221 5 study study NN cord-006870-f5w6fw6q 2221 6 were be VBD cord-006870-f5w6fw6q 2221 7 obtained obtain VBN cord-006870-f5w6fw6q 2221 8 from from IN cord-006870-f5w6fw6q 2221 9 the the DT cord-006870-f5w6fw6q 2221 10 nationwide nationwide JJ cord-006870-f5w6fw6q 2221 11 sample sample NN cord-006870-f5w6fw6q 2221 12 cohort cohort NN cord-006870-f5w6fw6q 2221 13 comprising comprise VBG cord-006870-f5w6fw6q 2221 14 1,025,340 1,025,340 CD cord-006870-f5w6fw6q 2221 15 individuals individual NNS cord-006870-f5w6fw6q 2221 16 ( ( -LRB- cord-006870-f5w6fw6q 2221 17 2 2 CD cord-006870-f5w6fw6q 2221 18 % % NN cord-006870-f5w6fw6q 2221 19 of of IN cord-006870-f5w6fw6q 2221 20 entire entire JJ cord-006870-f5w6fw6q 2221 21 population population NN cord-006870-f5w6fw6q 2221 22 in in IN cord-006870-f5w6fw6q 2221 23 Korea Korea NNP cord-006870-f5w6fw6q 2221 24 ) ) -RRB- cord-006870-f5w6fw6q 2221 25 which which WDT cord-006870-f5w6fw6q 2221 26 were be VBD cord-006870-f5w6fw6q 2221 27 established establish VBN cord-006870-f5w6fw6q 2221 28 by by IN cord-006870-f5w6fw6q 2221 29 Nationwide Nationwide NNP cord-006870-f5w6fw6q 2221 30 Health Health NNP cord-006870-f5w6fw6q 2221 31 Insurance Insurance NNP cord-006870-f5w6fw6q 2221 32 System System NNP cord-006870-f5w6fw6q 2221 33 . . . cord-006870-f5w6fw6q 2222 1 During during IN cord-006870-f5w6fw6q 2222 2 a a DT cord-006870-f5w6fw6q 2222 3 10-year 10-year CD cord-006870-f5w6fw6q 2222 4 follow follow NN cord-006870-f5w6fw6q 2222 5 - - HYPH cord-006870-f5w6fw6q 2222 6 up up NN cord-006870-f5w6fw6q 2222 7 period period NN cord-006870-f5w6fw6q 2222 8 , , , cord-006870-f5w6fw6q 2222 9 there there EX cord-006870-f5w6fw6q 2222 10 was be VBD cord-006870-f5w6fw6q 2222 11 16 16 CD cord-006870-f5w6fw6q 2222 12 , , , cord-006870-f5w6fw6q 2222 13 273 273 CD cord-006870-f5w6fw6q 2222 14 developed develop VBN cord-006870-f5w6fw6q 2222 15 AF af NN cord-006870-f5w6fw6q 2222 16 ( ( -LRB- cord-006870-f5w6fw6q 2222 17 1.58 1.58 CD cord-006870-f5w6fw6q 2222 18 % % NN cord-006870-f5w6fw6q 2222 19 ) ) -RRB- cord-006870-f5w6fw6q 2222 20 . . . cord-006870-f5w6fw6q 2223 1 the the DT cord-006870-f5w6fw6q 2223 2 incidence incidence NN cord-006870-f5w6fw6q 2223 3 of of IN cord-006870-f5w6fw6q 2223 4 patients patient NNS cord-006870-f5w6fw6q 2223 5 with with IN cord-006870-f5w6fw6q 2223 6 AF AF NNP cord-006870-f5w6fw6q 2223 7 remained remain VBD cord-006870-f5w6fw6q 2223 8 relatively relatively RB cord-006870-f5w6fw6q 2223 9 constant constant JJ cord-006870-f5w6fw6q 2223 10 during during IN cord-006870-f5w6fw6q 2223 11 study study NN cord-006870-f5w6fw6q 2223 12 period period NN cord-006870-f5w6fw6q 2223 13 ( ( -LRB- cord-006870-f5w6fw6q 2223 14 8.23 8.23 CD cord-006870-f5w6fw6q 2223 15 % % NN cord-006870-f5w6fw6q 2223 16 in in IN cord-006870-f5w6fw6q 2223 17 2004 2004 CD cord-006870-f5w6fw6q 2223 18 vs vs IN cord-006870-f5w6fw6q 2223 19 8.24 8.24 CD cord-006870-f5w6fw6q 2223 20 % % NN cord-006870-f5w6fw6q 2223 21 in in IN cord-006870-f5w6fw6q 2223 22 2013 2013 CD cord-006870-f5w6fw6q 2223 23 ) ) -RRB- cord-006870-f5w6fw6q 2223 24 . . . cord-006870-f5w6fw6q 2224 1 The the DT cord-006870-f5w6fw6q 2224 2 proportion proportion NN cord-006870-f5w6fw6q 2224 3 of of IN cord-006870-f5w6fw6q 2224 4 patients patient NNS cord-006870-f5w6fw6q 2224 5 with with IN cord-006870-f5w6fw6q 2224 6 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 2224 7 therapy therapy NN cord-006870-f5w6fw6q 2224 8 increased increase VBD cord-006870-f5w6fw6q 2224 9 from from IN cord-006870-f5w6fw6q 2224 10 18.5 18.5 CD cord-006870-f5w6fw6q 2224 11 % % NN cord-006870-f5w6fw6q 2224 12 in in IN cord-006870-f5w6fw6q 2224 13 2004 2004 CD cord-006870-f5w6fw6q 2224 14 to to IN cord-006870-f5w6fw6q 2224 15 36.5 36.5 CD cord-006870-f5w6fw6q 2224 16 % % NN cord-006870-f5w6fw6q 2224 17 in in IN cord-006870-f5w6fw6q 2224 18 2013 2013 CD cord-006870-f5w6fw6q 2224 19 significantly significantly RB cord-006870-f5w6fw6q 2224 20 ( ( -LRB- cord-006870-f5w6fw6q 2224 21 p p NN cord-006870-f5w6fw6q 2224 22 for for IN cord-006870-f5w6fw6q 2224 23 trends trend NNS cord-006870-f5w6fw6q 2224 24 < < XX cord-006870-f5w6fw6q 2224 25 0.001 0.001 CD cord-006870-f5w6fw6q 2224 26 ) ) -RRB- cord-006870-f5w6fw6q 2224 27 . . . cord-006870-f5w6fw6q 2225 1 However however RB cord-006870-f5w6fw6q 2225 2 , , , cord-006870-f5w6fw6q 2225 3 the the DT cord-006870-f5w6fw6q 2225 4 proportion proportion NN cord-006870-f5w6fw6q 2225 5 of of IN cord-006870-f5w6fw6q 2225 6 patients patient NNS cord-006870-f5w6fw6q 2225 7 with with IN cord-006870-f5w6fw6q 2225 8 antiplatelet antiplatelet JJ cord-006870-f5w6fw6q 2225 9 agents agent NNS cord-006870-f5w6fw6q 2225 10 was be VBD cord-006870-f5w6fw6q 2225 11 higher high JJR cord-006870-f5w6fw6q 2225 12 than than IN cord-006870-f5w6fw6q 2225 13 with with IN cord-006870-f5w6fw6q 2225 14 oral oral JJ cord-006870-f5w6fw6q 2225 15 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2225 16 . . . cord-006870-f5w6fw6q 2226 1 AF AF NNP cord-006870-f5w6fw6q 2226 2 steadily steadily RB cord-006870-f5w6fw6q 2226 3 increased increase VBD cord-006870-f5w6fw6q 2226 4 over over IN cord-006870-f5w6fw6q 2226 5 recent recent JJ cord-006870-f5w6fw6q 2226 6 10 10 CD cord-006870-f5w6fw6q 2226 7 years year NNS cord-006870-f5w6fw6q 2226 8 in in IN cord-006870-f5w6fw6q 2226 9 Korea Korea NNP cord-006870-f5w6fw6q 2226 10 . . . cord-006870-f5w6fw6q 2227 1 However however RB cord-006870-f5w6fw6q 2227 2 , , , cord-006870-f5w6fw6q 2227 3 only only RB cord-006870-f5w6fw6q 2227 4 36.5 36.5 CD cord-006870-f5w6fw6q 2227 5 % % NN cord-006870-f5w6fw6q 2227 6 of of IN cord-006870-f5w6fw6q 2227 7 AF AF NNP cord-006870-f5w6fw6q 2227 8 patients patient NNS cord-006870-f5w6fw6q 2227 9 were be VBD cord-006870-f5w6fw6q 2227 10 receiving receive VBG cord-006870-f5w6fw6q 2227 11 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 2227 12 therapy therapy NN cord-006870-f5w6fw6q 2227 13 . . . cord-006870-f5w6fw6q 2228 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2228 2 study study NN cord-006870-f5w6fw6q 2228 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 2228 4 that that IN cord-006870-f5w6fw6q 2228 5 there there EX cord-006870-f5w6fw6q 2228 6 was be VBD cord-006870-f5w6fw6q 2228 7 huge huge JJ cord-006870-f5w6fw6q 2228 8 gap gap NN cord-006870-f5w6fw6q 2228 9 between between IN cord-006870-f5w6fw6q 2228 10 the the DT cord-006870-f5w6fw6q 2228 11 clinical clinical JJ cord-006870-f5w6fw6q 2228 12 practice practice NN cord-006870-f5w6fw6q 2228 13 and and CC cord-006870-f5w6fw6q 2228 14 treatment treatment NN cord-006870-f5w6fw6q 2228 15 guideline guideline NN cord-006870-f5w6fw6q 2228 16 in in IN cord-006870-f5w6fw6q 2228 17 antithrombotic antithrombotic JJ cord-006870-f5w6fw6q 2228 18 medication medication NN cord-006870-f5w6fw6q 2228 19 for for IN cord-006870-f5w6fw6q 2228 20 AF AF NNP cord-006870-f5w6fw6q 2228 21 patients patient NNS cord-006870-f5w6fw6q 2228 22 in in IN cord-006870-f5w6fw6q 2228 23 Korea Korea NNP cord-006870-f5w6fw6q 2228 24 over over IN cord-006870-f5w6fw6q 2228 25 the the DT cord-006870-f5w6fw6q 2228 26 past past JJ cord-006870-f5w6fw6q 2228 27 decade decade NN cord-006870-f5w6fw6q 2228 28 . . . cord-006870-f5w6fw6q 2229 1 OhioHealth OhioHealth NNP cord-006870-f5w6fw6q 2230 1 ( ( -LRB- cord-006870-f5w6fw6q 2230 2 OH oh UH cord-006870-f5w6fw6q 2230 3 ) ) -RRB- cord-006870-f5w6fw6q 2230 4 possesses possess VBZ cord-006870-f5w6fw6q 2230 5 one one CD cord-006870-f5w6fw6q 2230 6 of of IN cord-006870-f5w6fw6q 2230 7 the the DT cord-006870-f5w6fw6q 2230 8 nation nation NN cord-006870-f5w6fw6q 2230 9 's 's POS cord-006870-f5w6fw6q 2230 10 largest large JJS cord-006870-f5w6fw6q 2230 11 neuroscience neuroscience NN cord-006870-f5w6fw6q 2230 12 programs program NNS cord-006870-f5w6fw6q 2230 13 and and CC cord-006870-f5w6fw6q 2230 14 is be VBZ cord-006870-f5w6fw6q 2230 15 the the DT cord-006870-f5w6fw6q 2230 16 leading leading JJ cord-006870-f5w6fw6q 2230 17 volume volume NN cord-006870-f5w6fw6q 2230 18 provider provider NN cord-006870-f5w6fw6q 2230 19 of of IN cord-006870-f5w6fw6q 2230 20 stroke stroke NN cord-006870-f5w6fw6q 2230 21 care care NN cord-006870-f5w6fw6q 2230 22 in in IN cord-006870-f5w6fw6q 2230 23 Ohio Ohio NNP cord-006870-f5w6fw6q 2230 24 . . . cord-006870-f5w6fw6q 2231 1 OH oh UH cord-006870-f5w6fw6q 2231 2 is be VBZ cord-006870-f5w6fw6q 2231 3 comprised comprise VBN cord-006870-f5w6fw6q 2231 4 of of IN cord-006870-f5w6fw6q 2231 5 12 12 CD cord-006870-f5w6fw6q 2231 6 hospital hospital NN cord-006870-f5w6fw6q 2231 7 - - HYPH cord-006870-f5w6fw6q 2231 8 based base VBN cord-006870-f5w6fw6q 2231 9 sites site NNS cord-006870-f5w6fw6q 2231 10 , , , cord-006870-f5w6fw6q 2231 11 4 4 CD cord-006870-f5w6fw6q 2231 12 primary primary JJ cord-006870-f5w6fw6q 2231 13 stroke stroke NN cord-006870-f5w6fw6q 2231 14 centers center NNS cord-006870-f5w6fw6q 2231 15 , , , cord-006870-f5w6fw6q 2231 16 1 1 CD cord-006870-f5w6fw6q 2231 17 comprehensive comprehensive JJ cord-006870-f5w6fw6q 2231 18 stroke stroke NN cord-006870-f5w6fw6q 2231 19 center center NN cord-006870-f5w6fw6q 2231 20 , , , cord-006870-f5w6fw6q 2231 21 and and CC cord-006870-f5w6fw6q 2231 22 a a DT cord-006870-f5w6fw6q 2231 23 virtual virtual JJ cord-006870-f5w6fw6q 2231 24 health health NN cord-006870-f5w6fw6q 2231 25 ( ( -LRB- cord-006870-f5w6fw6q 2231 26 VH VH NNP cord-006870-f5w6fw6q 2231 27 ) ) -RRB- cord-006870-f5w6fw6q 2231 28 stroke stroke NN cord-006870-f5w6fw6q 2231 29 network network NN cord-006870-f5w6fw6q 2231 30 that that WDT cord-006870-f5w6fw6q 2231 31 serves serve VBZ cord-006870-f5w6fw6q 2231 32 24 24 CD cord-006870-f5w6fw6q 2231 33 hospitals hospital NNS cord-006870-f5w6fw6q 2231 34 throughout throughout IN cord-006870-f5w6fw6q 2231 35 the the DT cord-006870-f5w6fw6q 2231 36 state state NN cord-006870-f5w6fw6q 2231 37 . . . cord-006870-f5w6fw6q 2232 1 In in IN cord-006870-f5w6fw6q 2232 2 August August NNP cord-006870-f5w6fw6q 2232 3 2016 2016 CD cord-006870-f5w6fw6q 2232 4 , , , cord-006870-f5w6fw6q 2232 5 stroke stroke NN cord-006870-f5w6fw6q 2232 6 services service NNS cord-006870-f5w6fw6q 2232 7 at at IN cord-006870-f5w6fw6q 2232 8 OhioHealth OhioHealth NNP cord-006870-f5w6fw6q 2232 9 were be VBD cord-006870-f5w6fw6q 2232 10 restructured restructure VBN cord-006870-f5w6fw6q 2232 11 to to TO cord-006870-f5w6fw6q 2232 12 enable enable VB cord-006870-f5w6fw6q 2232 13 dedicated dedicated JJ cord-006870-f5w6fw6q 2232 14 clinical clinical JJ cord-006870-f5w6fw6q 2232 15 time time NN cord-006870-f5w6fw6q 2232 16 for for IN cord-006870-f5w6fw6q 2232 17 VH VH NNP cord-006870-f5w6fw6q 2232 18 providers provider NNS cord-006870-f5w6fw6q 2232 19 , , , cord-006870-f5w6fw6q 2232 20 require require VBP cord-006870-f5w6fw6q 2232 21 expertise expertise NN cord-006870-f5w6fw6q 2232 22 , , , cord-006870-f5w6fw6q 2232 23 training training NN cord-006870-f5w6fw6q 2232 24 , , , cord-006870-f5w6fw6q 2232 25 and and CC cord-006870-f5w6fw6q 2232 26 quality quality NN cord-006870-f5w6fw6q 2232 27 review review NN cord-006870-f5w6fw6q 2232 28 participation participation NN cord-006870-f5w6fw6q 2232 29 for for IN cord-006870-f5w6fw6q 2232 30 stroke stroke NN cord-006870-f5w6fw6q 2232 31 responders responder NNS cord-006870-f5w6fw6q 2232 32 , , , cord-006870-f5w6fw6q 2232 33 streamline streamline VB cord-006870-f5w6fw6q 2232 34 activation activation NN cord-006870-f5w6fw6q 2232 35 algorithms algorithm NNS cord-006870-f5w6fw6q 2232 36 to to TO cord-006870-f5w6fw6q 2232 37 limit limit VB cord-006870-f5w6fw6q 2232 38 hand hand NN cord-006870-f5w6fw6q 2232 39 - - HYPH cord-006870-f5w6fw6q 2232 40 offs off NNS cord-006870-f5w6fw6q 2232 41 , , , cord-006870-f5w6fw6q 2232 42 and and CC cord-006870-f5w6fw6q 2232 43 eliminate eliminate VB cord-006870-f5w6fw6q 2232 44 identified identify VBN cord-006870-f5w6fw6q 2232 45 barriers barrier NNS cord-006870-f5w6fw6q 2232 46 to to IN cord-006870-f5w6fw6q 2232 47 VH VH NNP cord-006870-f5w6fw6q 2232 48 consultation consultation NN cord-006870-f5w6fw6q 2232 49 . . . cord-006870-f5w6fw6q 2233 1 A a DT cord-006870-f5w6fw6q 2233 2 6 6 CD cord-006870-f5w6fw6q 2233 3 month month NN cord-006870-f5w6fw6q 2233 4 interim interim JJ cord-006870-f5w6fw6q 2233 5 analysis analysis NN cord-006870-f5w6fw6q 2233 6 was be VBD cord-006870-f5w6fw6q 2233 7 planned plan VBN cord-006870-f5w6fw6q 2233 8 to to TO cord-006870-f5w6fw6q 2233 9 assess assess VB cord-006870-f5w6fw6q 2233 10 the the DT cord-006870-f5w6fw6q 2233 11 impact impact NN cord-006870-f5w6fw6q 2233 12 of of IN cord-006870-f5w6fw6q 2233 13 these these DT cord-006870-f5w6fw6q 2233 14 changes change NNS cord-006870-f5w6fw6q 2233 15 ( ( -LRB- cord-006870-f5w6fw6q 2233 16 termed term VBN cord-006870-f5w6fw6q 2233 17 " " `` cord-006870-f5w6fw6q 2233 18 Stroke Stroke NNP cord-006870-f5w6fw6q 2233 19 2.0 2.0 CD cord-006870-f5w6fw6q 2233 20 " " '' cord-006870-f5w6fw6q 2233 21 ) ) -RRB- cord-006870-f5w6fw6q 2233 22 . . . cord-006870-f5w6fw6q 2234 1 Comparative comparative JJ cord-006870-f5w6fw6q 2234 2 analyses analysis NNS cord-006870-f5w6fw6q 2234 3 were be VBD cord-006870-f5w6fw6q 2234 4 performed perform VBN cord-006870-f5w6fw6q 2234 5 between between IN cord-006870-f5w6fw6q 2234 6 the the DT cord-006870-f5w6fw6q 2234 7 first first JJ cord-006870-f5w6fw6q 2234 8 6 6 CD cord-006870-f5w6fw6q 2234 9 months month NNS cord-006870-f5w6fw6q 2234 10 of of IN cord-006870-f5w6fw6q 2234 11 Stroke stroke NN cord-006870-f5w6fw6q 2234 12 2.0 2.0 CD cord-006870-f5w6fw6q 2234 13 and and CC cord-006870-f5w6fw6q 2234 14 the the DT cord-006870-f5w6fw6q 2234 15 similar similar JJ cord-006870-f5w6fw6q 2234 16 time time NN cord-006870-f5w6fw6q 2234 17 period period NN cord-006870-f5w6fw6q 2234 18 of of IN cord-006870-f5w6fw6q 2234 19 the the DT cord-006870-f5w6fw6q 2234 20 year year NN cord-006870-f5w6fw6q 2234 21 prior prior RB cord-006870-f5w6fw6q 2234 22 to to IN cord-006870-f5w6fw6q 2234 23 restructuring restructuring NN cord-006870-f5w6fw6q 2234 24 . . . cord-006870-f5w6fw6q 2235 1 Pre pre JJ cord-006870-f5w6fw6q 2235 2 - - JJ cord-006870-f5w6fw6q 2235 3 defined define VBN cord-006870-f5w6fw6q 2235 4 metrics metric NNS cord-006870-f5w6fw6q 2235 5 included include VBD cord-006870-f5w6fw6q 2235 6 consultation consultation NN cord-006870-f5w6fw6q 2235 7 volume volume NN cord-006870-f5w6fw6q 2235 8 , , , cord-006870-f5w6fw6q 2235 9 VH VH NNP cord-006870-f5w6fw6q 2235 10 response response NN cord-006870-f5w6fw6q 2235 11 time time NN cord-006870-f5w6fw6q 2235 12 , , , cord-006870-f5w6fw6q 2235 13 IV IV NNP cord-006870-f5w6fw6q 2235 14 - - HYPH cord-006870-f5w6fw6q 2235 15 tPA tPA NNP cord-006870-f5w6fw6q 2235 16 time time NN cord-006870-f5w6fw6q 2235 17 to to IN cord-006870-f5w6fw6q 2235 18 treatment treatment NN cord-006870-f5w6fw6q 2235 19 , , , cord-006870-f5w6fw6q 2235 20 research research NN cord-006870-f5w6fw6q 2235 21 enrollment enrollment NN cord-006870-f5w6fw6q 2235 22 volume volume NN cord-006870-f5w6fw6q 2235 23 , , , cord-006870-f5w6fw6q 2235 24 endovascular endovascular JJ cord-006870-f5w6fw6q 2235 25 referral referral JJ cord-006870-f5w6fw6q 2235 26 rate rate NN cord-006870-f5w6fw6q 2235 27 and and CC cord-006870-f5w6fw6q 2235 28 time time NN cord-006870-f5w6fw6q 2235 29 to to IN cord-006870-f5w6fw6q 2235 30 treatment treatment NN cord-006870-f5w6fw6q 2235 31 , , , cord-006870-f5w6fw6q 2235 32 ischemic ischemic JJ cord-006870-f5w6fw6q 2235 33 stroke stroke NN cord-006870-f5w6fw6q 2235 34 ( ( -LRB- cord-006870-f5w6fw6q 2235 35 IS be VBZ cord-006870-f5w6fw6q 2235 36 ) ) -RRB- cord-006870-f5w6fw6q 2235 37 observed observe VBN cord-006870-f5w6fw6q 2235 38 : : : cord-006870-f5w6fw6q 2235 39 expected expect VBN cord-006870-f5w6fw6q 2236 1 ( ( -LRB- cord-006870-f5w6fw6q 2236 2 O o UH cord-006870-f5w6fw6q 2236 3 : : : cord-006870-f5w6fw6q 2236 4 E e NN cord-006870-f5w6fw6q 2236 5 ) ) -RRB- cord-006870-f5w6fw6q 2236 6 mortality mortality NN cord-006870-f5w6fw6q 2236 7 data datum NNS cord-006870-f5w6fw6q 2236 8 , , , cord-006870-f5w6fw6q 2236 9 and and CC cord-006870-f5w6fw6q 2236 10 patient patient JJ cord-006870-f5w6fw6q 2236 11 retention retention NN cord-006870-f5w6fw6q 2236 12 rate rate NN cord-006870-f5w6fw6q 2236 13 at at IN cord-006870-f5w6fw6q 2236 14 associate associate JJ cord-006870-f5w6fw6q 2236 15 VH VH NNP cord-006870-f5w6fw6q 2236 16 sites site NNS cord-006870-f5w6fw6q 2236 17 . . . cord-006870-f5w6fw6q 2237 1 During during IN cord-006870-f5w6fw6q 2237 2 the the DT cord-006870-f5w6fw6q 2237 3 first first JJ cord-006870-f5w6fw6q 2237 4 6 6 CD cord-006870-f5w6fw6q 2237 5 months month NNS cord-006870-f5w6fw6q 2237 6 of of IN cord-006870-f5w6fw6q 2237 7 Stroke stroke NN cord-006870-f5w6fw6q 2237 8 2.0 2.0 CD cord-006870-f5w6fw6q 2237 9 , , , cord-006870-f5w6fw6q 2237 10 2007 2007 CD cord-006870-f5w6fw6q 2237 11 encounters encounter NNS cord-006870-f5w6fw6q 2237 12 were be VBD cord-006870-f5w6fw6q 2237 13 seen see VBN cord-006870-f5w6fw6q 2237 14 ( ( -LRB- cord-006870-f5w6fw6q 2237 15 historical historical JJ cord-006870-f5w6fw6q 2237 16 700 700 CD cord-006870-f5w6fw6q 2237 17 ) ) -RRB- cord-006870-f5w6fw6q 2237 18 with with IN cord-006870-f5w6fw6q 2237 19 a a DT cord-006870-f5w6fw6q 2237 20 mean mean JJ cord-006870-f5w6fw6q 2237 21 activation activation NN cord-006870-f5w6fw6q 2237 22 to to IN cord-006870-f5w6fw6q 2237 23 VH VH NNP cord-006870-f5w6fw6q 2237 24 log log NN cord-006870-f5w6fw6q 2237 25 in in IN cord-006870-f5w6fw6q 2237 26 of of IN cord-006870-f5w6fw6q 2237 27 4.3 4.3 CD cord-006870-f5w6fw6q 2237 28 minutes minute NNS cord-006870-f5w6fw6q 2237 29 . . . cord-006870-f5w6fw6q 2238 1 Both both DT cord-006870-f5w6fw6q 2238 2 volume volume NN cord-006870-f5w6fw6q 2238 3 of of IN cord-006870-f5w6fw6q 2238 4 patients patient NNS cord-006870-f5w6fw6q 2238 5 treated treat VBN cord-006870-f5w6fw6q 2238 6 with with IN cord-006870-f5w6fw6q 2238 7 IV IV NNP cord-006870-f5w6fw6q 2238 8 - - HYPH cord-006870-f5w6fw6q 2238 9 tPA tPA NNP cord-006870-f5w6fw6q 2238 10 ( ( -LRB- cord-006870-f5w6fw6q 2238 11 154 154 CD cord-006870-f5w6fw6q 2238 12 vs. vs. IN cord-006870-f5w6fw6q 2238 13 96 96 CD cord-006870-f5w6fw6q 2238 14 , , , cord-006870-f5w6fw6q 2238 15 p p NN cord-006870-f5w6fw6q 2238 16 < < XX cord-006870-f5w6fw6q 2238 17 0.05 0.05 CD cord-006870-f5w6fw6q 2238 18 ) ) -RRB- cord-006870-f5w6fw6q 2238 19 and and CC cord-006870-f5w6fw6q 2238 20 mean mean VB cord-006870-f5w6fw6q 2238 21 treatment treatment NN cord-006870-f5w6fw6q 2238 22 times time NNS cord-006870-f5w6fw6q 2238 23 ( ( -LRB- cord-006870-f5w6fw6q 2238 24 63 63 CD cord-006870-f5w6fw6q 2238 25 vs. vs. NN cord-006870-f5w6fw6q 2238 26 86 86 CD cord-006870-f5w6fw6q 2238 27 minutes minute NNS cord-006870-f5w6fw6q 2238 28 ; ; : cord-006870-f5w6fw6q 2238 29 p p NN cord-006870-f5w6fw6q 2238 30 < < XX cord-006870-f5w6fw6q 2238 31 0.005 0.005 CD cord-006870-f5w6fw6q 2238 32 ) ) -RRB- cord-006870-f5w6fw6q 2238 33 were be VBD cord-006870-f5w6fw6q 2238 34 significantly significantly RB cord-006870-f5w6fw6q 2238 35 reduced reduce VBN cord-006870-f5w6fw6q 2238 36 . . . cord-006870-f5w6fw6q 2239 1 Mean mean JJ cord-006870-f5w6fw6q 2239 2 time time NN cord-006870-f5w6fw6q 2239 3 to to IN cord-006870-f5w6fw6q 2239 4 endovascular endovascular JJ cord-006870-f5w6fw6q 2239 5 intervention intervention NN cord-006870-f5w6fw6q 2239 6 was be VBD cord-006870-f5w6fw6q 2239 7 less less JJR cord-006870-f5w6fw6q 2239 8 during during IN cord-006870-f5w6fw6q 2239 9 Stroke Stroke NNP cord-006870-f5w6fw6q 2239 10 2.0 2.0 CD cord-006870-f5w6fw6q 2239 11 ( ( -LRB- cord-006870-f5w6fw6q 2239 12 98 98 CD cord-006870-f5w6fw6q 2239 13 vs. vs. NN cord-006870-f5w6fw6q 2239 14 140 140 CD cord-006870-f5w6fw6q 2239 15 minutes minute NNS cord-006870-f5w6fw6q 2239 16 , , , cord-006870-f5w6fw6q 2239 17 p p NN cord-006870-f5w6fw6q 2239 18 < < XX cord-006870-f5w6fw6q 2239 19 0.05 0.05 CD cord-006870-f5w6fw6q 2239 20 ) ) -RRB- cord-006870-f5w6fw6q 2239 21 . . . cord-006870-f5w6fw6q 2240 1 System system NN cord-006870-f5w6fw6q 2240 2 - - HYPH cord-006870-f5w6fw6q 2240 3 wide wide JJ cord-006870-f5w6fw6q 2240 4 O o NN cord-006870-f5w6fw6q 2241 1 : : : cord-006870-f5w6fw6q 2241 2 E e NN cord-006870-f5w6fw6q 2241 3 mortality mortality NN cord-006870-f5w6fw6q 2241 4 was be VBD cord-006870-f5w6fw6q 2241 5 reduced reduce VBN cord-006870-f5w6fw6q 2241 6 after after IN cord-006870-f5w6fw6q 2241 7 restructuring restructure VBG cord-006870-f5w6fw6q 2241 8 ( ( -LRB- cord-006870-f5w6fw6q 2241 9 0.513 0.513 CD cord-006870-f5w6fw6q 2241 10 vs. vs. IN cord-006870-f5w6fw6q 2241 11 0.704 0.704 CD cord-006870-f5w6fw6q 2241 12 , , , cord-006870-f5w6fw6q 2241 13 p p NN cord-006870-f5w6fw6q 2241 14 < < XX cord-006870-f5w6fw6q 2241 15 0.05 0.05 CD cord-006870-f5w6fw6q 2241 16 ) ) -RRB- cord-006870-f5w6fw6q 2241 17 , , , cord-006870-f5w6fw6q 2241 18 accounting account VBG cord-006870-f5w6fw6q 2241 19 for for IN cord-006870-f5w6fw6q 2241 20 21 21 CD cord-006870-f5w6fw6q 2241 21 additional additional JJ cord-006870-f5w6fw6q 2241 22 lives life NNS cord-006870-f5w6fw6q 2241 23 saved save VBN cord-006870-f5w6fw6q 2241 24 . . . cord-006870-f5w6fw6q 2242 1 Acute acute JJ cord-006870-f5w6fw6q 2242 2 stroke stroke NN cord-006870-f5w6fw6q 2242 3 research research NN cord-006870-f5w6fw6q 2242 4 enrollment enrollment NN cord-006870-f5w6fw6q 2242 5 doubled double VBD cord-006870-f5w6fw6q 2242 6 ( ( -LRB- cord-006870-f5w6fw6q 2242 7 77 77 CD cord-006870-f5w6fw6q 2242 8 vs. vs. IN cord-006870-f5w6fw6q 2242 9 38 38 CD cord-006870-f5w6fw6q 2242 10 ) ) -RRB- cord-006870-f5w6fw6q 2242 11 during during IN cord-006870-f5w6fw6q 2242 12 this this DT cord-006870-f5w6fw6q 2242 13 same same JJ cord-006870-f5w6fw6q 2242 14 period period NN cord-006870-f5w6fw6q 2242 15 . . . cord-006870-f5w6fw6q 2243 1 Transfer transfer NN cord-006870-f5w6fw6q 2243 2 rates rate NNS cord-006870-f5w6fw6q 2243 3 to to IN cord-006870-f5w6fw6q 2243 4 VH VH NNP cord-006870-f5w6fw6q 2243 5 hub hub NN cord-006870-f5w6fw6q 2243 6 were be VBD cord-006870-f5w6fw6q 2243 7 unchanged unchanged JJ cord-006870-f5w6fw6q 2243 8 ( ( -LRB- cord-006870-f5w6fw6q 2243 9 59 59 CD cord-006870-f5w6fw6q 2243 10 vs. vs. IN cord-006870-f5w6fw6q 2243 11 59 59 CD cord-006870-f5w6fw6q 2243 12 % % NN cord-006870-f5w6fw6q 2243 13 , , , cord-006870-f5w6fw6q 2243 14 p p NN cord-006870-f5w6fw6q 2243 15 = = SYM cord-006870-f5w6fw6q 2243 16 1.0 1.0 CD cord-006870-f5w6fw6q 2243 17 ) ) -RRB- cord-006870-f5w6fw6q 2243 18 . . . cord-006870-f5w6fw6q 2244 1 Strategic strategic JJ cord-006870-f5w6fw6q 2244 2 changes change NNS cord-006870-f5w6fw6q 2244 3 in in IN cord-006870-f5w6fw6q 2244 4 staffing staffing NN cord-006870-f5w6fw6q 2244 5 , , , cord-006870-f5w6fw6q 2244 6 expertise expertise NN cord-006870-f5w6fw6q 2244 7 , , , cord-006870-f5w6fw6q 2244 8 VH VH NNP cord-006870-f5w6fw6q 2244 9 structure structure NN cord-006870-f5w6fw6q 2244 10 , , , cord-006870-f5w6fw6q 2244 11 and and CC cord-006870-f5w6fw6q 2244 12 access access NN cord-006870-f5w6fw6q 2244 13 can can MD cord-006870-f5w6fw6q 2244 14 have have VB cord-006870-f5w6fw6q 2244 15 profound profound JJ cord-006870-f5w6fw6q 2244 16 and and CC cord-006870-f5w6fw6q 2244 17 positive positive JJ cord-006870-f5w6fw6q 2244 18 changes change NNS cord-006870-f5w6fw6q 2244 19 on on IN cord-006870-f5w6fw6q 2244 20 a a DT cord-006870-f5w6fw6q 2244 21 well well RB cord-006870-f5w6fw6q 2244 22 - - HYPH cord-006870-f5w6fw6q 2244 23 functioning function VBG cord-006870-f5w6fw6q 2244 24 stroke stroke NN cord-006870-f5w6fw6q 2244 25 system system NN cord-006870-f5w6fw6q 2244 26 . . . cord-006870-f5w6fw6q 2245 1 Strokes stroke NNS cord-006870-f5w6fw6q 2245 2 due due JJ cord-006870-f5w6fw6q 2245 3 to to IN cord-006870-f5w6fw6q 2245 4 CNS cns JJ cord-006870-f5w6fw6q 2245 5 fungal fungal JJ cord-006870-f5w6fw6q 2245 6 infections infection NNS cord-006870-f5w6fw6q 2245 7 ( ( -LRB- cord-006870-f5w6fw6q 2245 8 SCFI SCFI NNP cord-006870-f5w6fw6q 2245 9 ) ) -RRB- cord-006870-f5w6fw6q 2245 10 are be VBP cord-006870-f5w6fw6q 2245 11 often often RB cord-006870-f5w6fw6q 2245 12 misdiagnosed misdiagnose VBN cord-006870-f5w6fw6q 2245 13 . . . cord-006870-f5w6fw6q 2246 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 2246 2 study study NN cord-006870-f5w6fw6q 2246 3 of of IN cord-006870-f5w6fw6q 2246 4 electronically electronically RB cord-006870-f5w6fw6q 2246 5 - - HYPH cord-006870-f5w6fw6q 2246 6 extracted extract VBN cord-006870-f5w6fw6q 2246 7 records record NNS cord-006870-f5w6fw6q 2246 8 in in IN cord-006870-f5w6fw6q 2246 9 patients patient NNS cord-006870-f5w6fw6q 2246 10 with with IN cord-006870-f5w6fw6q 2246 11 strokes stroke NNS cord-006870-f5w6fw6q 2246 12 & & CC cord-006870-f5w6fw6q 2246 13 positive positive JJ cord-006870-f5w6fw6q 2246 14 fungal fungal JJ cord-006870-f5w6fw6q 2246 15 studies study NNS cord-006870-f5w6fw6q 2246 16 , , , cord-006870-f5w6fw6q 2246 17 from from IN cord-006870-f5w6fw6q 2246 18 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 2246 19 fluid fluid NN cord-006870-f5w6fw6q 2246 20 ( ( -LRB- cord-006870-f5w6fw6q 2246 21 CSF CSF NNP cord-006870-f5w6fw6q 2246 22 ) ) -RRB- cord-006870-f5w6fw6q 2246 23 or or CC cord-006870-f5w6fw6q 2246 24 brain brain NN cord-006870-f5w6fw6q 2246 25 biopsy biopsy NN cord-006870-f5w6fw6q 2246 26 . . . cord-006870-f5w6fw6q 2247 1 Other other JJ cord-006870-f5w6fw6q 2247 2 stroke stroke NN cord-006870-f5w6fw6q 2247 3 etiologies etiology NNS cord-006870-f5w6fw6q 2247 4 were be VBD cord-006870-f5w6fw6q 2247 5 excluded exclude VBN cord-006870-f5w6fw6q 2247 6 . . . cord-006870-f5w6fw6q 2248 1 Thirteen thirteen CD cord-006870-f5w6fw6q 2248 2 patients patient NNS cord-006870-f5w6fw6q 2248 3 had have VBD cord-006870-f5w6fw6q 2248 4 SCFI SCFI VBN cord-006870-f5w6fw6q 2248 5 by by IN cord-006870-f5w6fw6q 2248 6 a a DT cord-006870-f5w6fw6q 2248 7 priori priori FW cord-006870-f5w6fw6q 2248 8 exclusion exclusion NN cord-006870-f5w6fw6q 2248 9 & & CC cord-006870-f5w6fw6q 2248 10 inclusion inclusion NN cord-006870-f5w6fw6q 2248 11 criteria criterion NNS cord-006870-f5w6fw6q 2248 12 . . . cord-006870-f5w6fw6q 2249 1 Nine nine CD cord-006870-f5w6fw6q 2249 2 were be VBD cord-006870-f5w6fw6q 2249 3 males male NNS cord-006870-f5w6fw6q 2249 4 . . . cord-006870-f5w6fw6q 2250 1 Mean mean JJ cord-006870-f5w6fw6q 2250 2 age age NN cord-006870-f5w6fw6q 2250 3 was be VBD cord-006870-f5w6fw6q 2250 4 53 53 CD cord-006870-f5w6fw6q 2250 5 + + SYM cord-006870-f5w6fw6q 2250 6 17 17 CD cord-006870-f5w6fw6q 2250 7 years year NNS cord-006870-f5w6fw6q 2250 8 . . . cord-006870-f5w6fw6q 2251 1 Symptoms symptom NNS cord-006870-f5w6fw6q 2251 2 were be VBD cord-006870-f5w6fw6q 2251 3 mild mild JJ cord-006870-f5w6fw6q 2251 4 [ [ -LRB- cord-006870-f5w6fw6q 2251 5 NIHSS NIHSS NNP cord-006870-f5w6fw6q 2251 6 6 6 CD cord-006870-f5w6fw6q 2251 7 ( ( -LRB- cord-006870-f5w6fw6q 2251 8 2 2 CD cord-006870-f5w6fw6q 2251 9 , , , cord-006870-f5w6fw6q 2251 10 9.5 9.5 CD cord-006870-f5w6fw6q 2251 11 ) ) -RRB- cord-006870-f5w6fw6q 2251 12 ( ( -LRB- cord-006870-f5w6fw6q 2251 13 median median NN cord-006870-f5w6fw6q 2251 14 and and CC cord-006870-f5w6fw6q 2251 15 IQR IQR NNP cord-006870-f5w6fw6q 2251 16 ) ) -RRB- cord-006870-f5w6fw6q 2251 17 ] ] -RRB- cord-006870-f5w6fw6q 2251 18 . . . cord-006870-f5w6fw6q 2252 1 Focal focal JJ cord-006870-f5w6fw6q 2252 2 deficits deficit NNS cord-006870-f5w6fw6q 2252 3 & & CC cord-006870-f5w6fw6q 2252 4 headaches headache NNS cord-006870-f5w6fw6q 2252 5 ( ( -LRB- cord-006870-f5w6fw6q 2252 6 both both DT cord-006870-f5w6fw6q 2252 7 76.9 76.9 CD cord-006870-f5w6fw6q 2252 8 % % NN cord-006870-f5w6fw6q 2252 9 ) ) -RRB- cord-006870-f5w6fw6q 2252 10 were be VBD cord-006870-f5w6fw6q 2252 11 common common JJ cord-006870-f5w6fw6q 2252 12 . . . cord-006870-f5w6fw6q 2253 1 Seventy seventy CD cord-006870-f5w6fw6q 2253 2 - - HYPH cord-006870-f5w6fw6q 2253 3 percent percent NN cord-006870-f5w6fw6q 2253 4 were be VBD cord-006870-f5w6fw6q 2253 5 immuno immuno JJ cord-006870-f5w6fw6q 2253 6 - - HYPH cord-006870-f5w6fw6q 2253 7 compromised compromised JJ cord-006870-f5w6fw6q 2253 8 ( ( -LRB- cord-006870-f5w6fw6q 2253 9 medications medication NNS cord-006870-f5w6fw6q 2253 10 , , , cord-006870-f5w6fw6q 2253 11 malignancy malignancy NN cord-006870-f5w6fw6q 2253 12 , , , cord-006870-f5w6fw6q 2253 13 transplant transplant NN cord-006870-f5w6fw6q 2253 14 recipients recipient NNS cord-006870-f5w6fw6q 2253 15 ) ) -RRB- cord-006870-f5w6fw6q 2253 16 . . . cord-006870-f5w6fw6q 2254 1 Clinical clinical JJ cord-006870-f5w6fw6q 2254 2 course course NN cord-006870-f5w6fw6q 2254 3 was be VBD cord-006870-f5w6fw6q 2254 4 indolent indolent JJ cord-006870-f5w6fw6q 2254 5 in in IN cord-006870-f5w6fw6q 2254 6 30.7 30.7 CD cord-006870-f5w6fw6q 2254 7 % % NN cord-006870-f5w6fw6q 2254 8 . . . cord-006870-f5w6fw6q 2255 1 Seventy seventy CD cord-006870-f5w6fw6q 2255 2 - - HYPH cord-006870-f5w6fw6q 2255 3 percent percent NN cord-006870-f5w6fw6q 2255 4 had have VBD cord-006870-f5w6fw6q 2255 5 poor poor JJ cord-006870-f5w6fw6q 2255 6 outcome outcome NN cord-006870-f5w6fw6q 2255 7 ( ( -LRB- cord-006870-f5w6fw6q 2255 8 2-LTAC 2-ltac CD cord-006870-f5w6fw6q 2255 9 , , , cord-006870-f5w6fw6q 2255 10 4-SNF 4-snf CD cord-006870-f5w6fw6q 2255 11 , , , cord-006870-f5w6fw6q 2255 12 2-dead 2-dead CD cord-006870-f5w6fw6q 2255 13 ) ) -RRB- cord-006870-f5w6fw6q 2255 14 . . . cord-006870-f5w6fw6q 2256 1 Ninety ninety CD cord-006870-f5w6fw6q 2256 2 - - HYPH cord-006870-f5w6fw6q 2256 3 two two CD cord-006870-f5w6fw6q 2256 4 percent percent NN cord-006870-f5w6fw6q 2256 5 had have VBD cord-006870-f5w6fw6q 2256 6 CSF CSF NNP cord-006870-f5w6fw6q 2256 7 pleocytosis pleocytosis NNP cord-006870-f5w6fw6q 2256 8 ( ( -LRB- cord-006870-f5w6fw6q 2256 9 Range:27 range:27 NN cord-006870-f5w6fw6q 2256 10 - - SYM cord-006870-f5w6fw6q 2256 11 471 471 CD cord-006870-f5w6fw6q 2256 12 ) ) -RRB- cord-006870-f5w6fw6q 2256 13 while while IN cord-006870-f5w6fw6q 2256 14 61 61 CD cord-006870-f5w6fw6q 2256 15 % % NN cord-006870-f5w6fw6q 2256 16 had have VBD cord-006870-f5w6fw6q 2256 17 CSF csf NN cord-006870-f5w6fw6q 2256 18 glucose glucose NN cord-006870-f5w6fw6q 2256 19 less less JJR cord-006870-f5w6fw6q 2256 20 than than IN cord-006870-f5w6fw6q 2256 21 40mg 40mg NN cord-006870-f5w6fw6q 2256 22 / / SYM cord-006870-f5w6fw6q 2256 23 dL dl NN cord-006870-f5w6fw6q 2257 1 ( ( -LRB- cord-006870-f5w6fw6q 2257 2 Range range NN cord-006870-f5w6fw6q 2257 3 : : : cord-006870-f5w6fw6q 2257 4 2 2 CD cord-006870-f5w6fw6q 2257 5 - - SYM cord-006870-f5w6fw6q 2257 6 37 37 CD cord-006870-f5w6fw6q 2257 7 ) ) -RRB- cord-006870-f5w6fw6q 2257 8 . . . cord-006870-f5w6fw6q 2258 1 Seventy seventy CD cord-006870-f5w6fw6q 2258 2 - - HYPH cord-006870-f5w6fw6q 2258 3 five five CD cord-006870-f5w6fw6q 2258 4 percent percent NN cord-006870-f5w6fw6q 2258 5 had have VBD cord-006870-f5w6fw6q 2258 6 lymphocytic lymphocytic JJ cord-006870-f5w6fw6q 2258 7 predominance predominance NN cord-006870-f5w6fw6q 2258 8 . . . cord-006870-f5w6fw6q 2259 1 Seven seven CD cord-006870-f5w6fw6q 2259 2 strokes stroke NNS cord-006870-f5w6fw6q 2259 3 were be VBD cord-006870-f5w6fw6q 2259 4 from from IN cord-006870-f5w6fw6q 2259 5 yeasts yeast NNS cord-006870-f5w6fw6q 2259 6 ( ( -LRB- cord-006870-f5w6fw6q 2259 7 4-Cryptococcus 4-cryptococcus CD cord-006870-f5w6fw6q 2259 8 , , , cord-006870-f5w6fw6q 2259 9 1-Coccidiomycosis 1-coccidiomycosis CD cord-006870-f5w6fw6q 2259 10 , , , cord-006870-f5w6fw6q 2259 11 1-Histoplasma 1-histoplasma CD cord-006870-f5w6fw6q 2259 12 , , , cord-006870-f5w6fw6q 2259 13 1-Candida 1-candida CD cord-006870-f5w6fw6q 2259 14 ) ) -RRB- cord-006870-f5w6fw6q 2259 15 and and CC cord-006870-f5w6fw6q 2259 16 6 6 CD cord-006870-f5w6fw6q 2259 17 from from IN cord-006870-f5w6fw6q 2259 18 molds mold NNS cord-006870-f5w6fw6q 2259 19 ( ( -LRB- cord-006870-f5w6fw6q 2259 20 4-zygomycetes 4-zygomycetes CD cord-006870-f5w6fw6q 2259 21 , , , cord-006870-f5w6fw6q 2259 22 2-Aspergillus 2-aspergillus CD cord-006870-f5w6fw6q 2259 23 ) ) -RRB- cord-006870-f5w6fw6q 2259 24 . . . cord-006870-f5w6fw6q 2260 1 Sixty sixty CD cord-006870-f5w6fw6q 2260 2 - - HYPH cord-006870-f5w6fw6q 2260 3 two two CD cord-006870-f5w6fw6q 2260 4 percent percent NN cord-006870-f5w6fw6q 2260 5 had have VBD cord-006870-f5w6fw6q 2260 6 posterior posterior JJ cord-006870-f5w6fw6q 2260 7 circulation circulation NN cord-006870-f5w6fw6q 2260 8 involvement involvement NN cord-006870-f5w6fw6q 2260 9 ( ( -LRB- cord-006870-f5w6fw6q 2260 10 71.4 71.4 CD cord-006870-f5w6fw6q 2260 11 % % NN cord-006870-f5w6fw6q 2260 12 yeast yeast NN cord-006870-f5w6fw6q 2260 13 vs vs IN cord-006870-f5w6fw6q 2260 14 50 50 CD cord-006870-f5w6fw6q 2260 15 % % NN cord-006870-f5w6fw6q 2260 16 molds mold NNS cord-006870-f5w6fw6q 2260 17 ) ) -RRB- cord-006870-f5w6fw6q 2260 18 . . . cord-006870-f5w6fw6q 2261 1 There there EX cord-006870-f5w6fw6q 2261 2 was be VBD cord-006870-f5w6fw6q 2261 3 lepto lepto NN cord-006870-f5w6fw6q 2261 4 - - HYPH cord-006870-f5w6fw6q 2261 5 meningeal meningeal JJ cord-006870-f5w6fw6q 2261 6 enhancement enhancement NN cord-006870-f5w6fw6q 2261 7 in in IN cord-006870-f5w6fw6q 2261 8 83 83 CD cord-006870-f5w6fw6q 2261 9 % % NN cord-006870-f5w6fw6q 2261 10 of of IN cord-006870-f5w6fw6q 2261 11 yeast yeast NN cord-006870-f5w6fw6q 2261 12 vs. vs. IN cord-006870-f5w6fw6q 2261 13 0 0 CD cord-006870-f5w6fw6q 2261 14 % % NN cord-006870-f5w6fw6q 2261 15 of of IN cord-006870-f5w6fw6q 2261 16 molds mold NNS cord-006870-f5w6fw6q 2261 17 infections infection NNS cord-006870-f5w6fw6q 2261 18 ( ( -LRB- cord-006870-f5w6fw6q 2261 19 p= p= JJ cord-006870-f5w6fw6q 2261 20 0.01 0.01 CD cord-006870-f5w6fw6q 2261 21 ) ) -RRB- cord-006870-f5w6fw6q 2261 22 . . . cord-006870-f5w6fw6q 2262 1 The the DT cord-006870-f5w6fw6q 2262 2 basal basal NN cord-006870-f5w6fw6q 2262 3 ganglia ganglion NNS cord-006870-f5w6fw6q 2262 4 ( ( -LRB- cord-006870-f5w6fw6q 2262 5 BG BG NNP cord-006870-f5w6fw6q 2262 6 ) ) -RRB- cord-006870-f5w6fw6q 2262 7 was be VBD cord-006870-f5w6fw6q 2262 8 involved involve VBN cord-006870-f5w6fw6q 2262 9 in in IN cord-006870-f5w6fw6q 2262 10 75 75 CD cord-006870-f5w6fw6q 2262 11 % % NN cord-006870-f5w6fw6q 2262 12 of of IN cord-006870-f5w6fw6q 2262 13 intravenous intravenous JJ cord-006870-f5w6fw6q 2262 14 - - HYPH cord-006870-f5w6fw6q 2262 15 drug drug NN cord-006870-f5w6fw6q 2262 16 users user NNS cord-006870-f5w6fw6q 2262 17 ( ( -LRB- cord-006870-f5w6fw6q 2262 18 IVDU IVDU NNP cord-006870-f5w6fw6q 2262 19 ) ) -RRB- cord-006870-f5w6fw6q 2262 20 vs. vs. IN cord-006870-f5w6fw6q 2262 21 0 0 CD cord-006870-f5w6fw6q 2262 22 % % NN cord-006870-f5w6fw6q 2262 23 of of IN cord-006870-f5w6fw6q 2262 24 non non JJ cord-006870-f5w6fw6q 2262 25 - - JJ cord-006870-f5w6fw6q 2262 26 IVDU ivdu JJ cord-006870-f5w6fw6q 2262 27 ( ( -LRB- cord-006870-f5w6fw6q 2262 28 p=0.01 p=0.01 JJ cord-006870-f5w6fw6q 2262 29 ) ) -RRB- cord-006870-f5w6fw6q 2262 30 . . . cord-006870-f5w6fw6q 2263 1 One one PRP cord-006870-f5w6fw6q 2263 2 had have VBD cord-006870-f5w6fw6q 2263 3 abnormal abnormal JJ cord-006870-f5w6fw6q 2263 4 CNS CNS NNP cord-006870-f5w6fw6q 2263 5 vessel vessel NN cord-006870-f5w6fw6q 2263 6 imaging imaging NN cord-006870-f5w6fw6q 2263 7 directly directly RB cord-006870-f5w6fw6q 2263 8 attributed attribute VBN cord-006870-f5w6fw6q 2263 9 to to IN cord-006870-f5w6fw6q 2263 10 the the DT cord-006870-f5w6fw6q 2263 11 ischemic ischemic JJ cord-006870-f5w6fw6q 2263 12 lesions lesion NNS cord-006870-f5w6fw6q 2263 13 . . . cord-006870-f5w6fw6q 2264 1 In in IN cord-006870-f5w6fw6q 2264 2 this this DT cord-006870-f5w6fw6q 2264 3 series series NN cord-006870-f5w6fw6q 2264 4 , , , cord-006870-f5w6fw6q 2264 5 patients patient NNS cord-006870-f5w6fw6q 2264 6 were be VBD cord-006870-f5w6fw6q 2264 7 young young JJ cord-006870-f5w6fw6q 2264 8 , , , cord-006870-f5w6fw6q 2264 9 immunocompromised immunocompromised JJ cord-006870-f5w6fw6q 2264 10 or or CC cord-006870-f5w6fw6q 2264 11 IVDU ivdu RB cord-006870-f5w6fw6q 2264 12 . . . cord-006870-f5w6fw6q 2265 1 Stroke stroke NN cord-006870-f5w6fw6q 2265 2 sizes size NNS cord-006870-f5w6fw6q 2265 3 & & CC cord-006870-f5w6fw6q 2265 4 clinical clinical JJ cord-006870-f5w6fw6q 2265 5 deficits deficit NNS cord-006870-f5w6fw6q 2265 6 were be VBD cord-006870-f5w6fw6q 2265 7 modest modest JJ cord-006870-f5w6fw6q 2265 8 with with IN cord-006870-f5w6fw6q 2265 9 no no DT cord-006870-f5w6fw6q 2265 10 angiographic angiographic JJ cord-006870-f5w6fw6q 2265 11 evidence evidence NN cord-006870-f5w6fw6q 2265 12 of of IN cord-006870-f5w6fw6q 2265 13 vasculitis vasculitis NN cord-006870-f5w6fw6q 2265 14 . . . cord-006870-f5w6fw6q 2266 1 Majority majority NN cord-006870-f5w6fw6q 2266 2 had have VBD cord-006870-f5w6fw6q 2266 3 CSF CSF NNP cord-006870-f5w6fw6q 2266 4 pleocytosis pleocytosis NNP cord-006870-f5w6fw6q 2266 5 & & CC cord-006870-f5w6fw6q 2266 6 hypoglycorrhachia hypoglycorrhachia NNP cord-006870-f5w6fw6q 2266 7 . . . cord-006870-f5w6fw6q 2267 1 Posterior posterior JJ cord-006870-f5w6fw6q 2267 2 circulation circulation NN cord-006870-f5w6fw6q 2267 3 involvement involvement NN cord-006870-f5w6fw6q 2267 4 was be VBD cord-006870-f5w6fw6q 2267 5 typical typical JJ cord-006870-f5w6fw6q 2267 6 . . . cord-006870-f5w6fw6q 2268 1 Lepto lepto NN cord-006870-f5w6fw6q 2268 2 - - HYPH cord-006870-f5w6fw6q 2268 3 meningeal meningeal JJ cord-006870-f5w6fw6q 2268 4 meningitis meningitis NN cord-006870-f5w6fw6q 2268 5 was be VBD cord-006870-f5w6fw6q 2268 6 only only RB cord-006870-f5w6fw6q 2268 7 seen see VBN cord-006870-f5w6fw6q 2268 8 in in IN cord-006870-f5w6fw6q 2268 9 yeast yeast NN cord-006870-f5w6fw6q 2268 10 infections infection NNS cord-006870-f5w6fw6q 2268 11 . . . cord-006870-f5w6fw6q 2269 1 The the DT cord-006870-f5w6fw6q 2269 2 BG BG NNP cord-006870-f5w6fw6q 2269 3 was be VBD cord-006870-f5w6fw6q 2269 4 spared spare VBN cord-006870-f5w6fw6q 2269 5 in in IN cord-006870-f5w6fw6q 2269 6 non non JJ cord-006870-f5w6fw6q 2269 7 - - JJ cord-006870-f5w6fw6q 2269 8 IVDU ivdu JJ cord-006870-f5w6fw6q 2269 9 but but CC cord-006870-f5w6fw6q 2269 10 common common JJ cord-006870-f5w6fw6q 2269 11 in in IN cord-006870-f5w6fw6q 2269 12 IVDU IVDU NNP cord-006870-f5w6fw6q 2269 13 . . . cord-006870-f5w6fw6q 2270 1 Mechanism mechanism NN cord-006870-f5w6fw6q 2270 2 of of IN cord-006870-f5w6fw6q 2270 3 stroke stroke NN cord-006870-f5w6fw6q 2270 4 in in IN cord-006870-f5w6fw6q 2270 5 yeast yeast NN cord-006870-f5w6fw6q 2270 6 infections infection NNS cord-006870-f5w6fw6q 2270 7 is be VBZ cord-006870-f5w6fw6q 2270 8 probably probably RB cord-006870-f5w6fw6q 2270 9 from from IN cord-006870-f5w6fw6q 2270 10 meningitis meningitis NN cord-006870-f5w6fw6q 2270 11 & & CC cord-006870-f5w6fw6q 2270 12 secondary secondary JJ cord-006870-f5w6fw6q 2270 13 involvement involvement NN cord-006870-f5w6fw6q 2270 14 of of IN cord-006870-f5w6fw6q 2270 15 small small JJ cord-006870-f5w6fw6q 2270 16 perforating perforate VBG cord-006870-f5w6fw6q 2270 17 branches branch NNS cord-006870-f5w6fw6q 2270 18 . . . cord-006870-f5w6fw6q 2271 1 Mechanism mechanism NN cord-006870-f5w6fw6q 2271 2 in in IN cord-006870-f5w6fw6q 2271 3 mold mold NN cord-006870-f5w6fw6q 2271 4 infections infection NNS cord-006870-f5w6fw6q 2271 5 in in IN cord-006870-f5w6fw6q 2271 6 immuno immuno JJ cord-006870-f5w6fw6q 2271 7 - - JJ cord-006870-f5w6fw6q 2271 8 competent competent JJ cord-006870-f5w6fw6q 2271 9 IVDU IVDU NNP cord-006870-f5w6fw6q 2271 10 is be VBZ cord-006870-f5w6fw6q 2271 11 probably probably RB cord-006870-f5w6fw6q 2271 12 direct direct JJ cord-006870-f5w6fw6q 2271 13 angio angio NN cord-006870-f5w6fw6q 2271 14 - - HYPH cord-006870-f5w6fw6q 2271 15 invasiveness invasiveness NN cord-006870-f5w6fw6q 2271 16 in in IN cord-006870-f5w6fw6q 2271 17 small small JJ cord-006870-f5w6fw6q 2271 18 vessels vessel NNS cord-006870-f5w6fw6q 2271 19 of of IN cord-006870-f5w6fw6q 2271 20 the the DT cord-006870-f5w6fw6q 2271 21 BG BG NNP cord-006870-f5w6fw6q 2271 22 . . . cord-006870-f5w6fw6q 2272 1 Outcomes outcome NNS cord-006870-f5w6fw6q 2272 2 are be VBP cord-006870-f5w6fw6q 2272 3 poor poor JJ cord-006870-f5w6fw6q 2272 4 in in IN cord-006870-f5w6fw6q 2272 5 spite spite NN cord-006870-f5w6fw6q 2272 6 of of IN cord-006870-f5w6fw6q 2272 7 therapy therapy NN cord-006870-f5w6fw6q 2272 8 . . . cord-006870-f5w6fw6q 2273 1 SCFI SCFI NNP cord-006870-f5w6fw6q 2273 2 should should MD cord-006870-f5w6fw6q 2273 3 be be VB cord-006870-f5w6fw6q 2273 4 considered consider VBN cord-006870-f5w6fw6q 2273 5 in in IN cord-006870-f5w6fw6q 2273 6 selected select VBN cord-006870-f5w6fw6q 2273 7 cases case NNS cord-006870-f5w6fw6q 2273 8 of of IN cord-006870-f5w6fw6q 2273 9 cryptogenic cryptogenic NNP cord-006870-f5w6fw6q 2273 10 ( ( -LRB- cord-006870-f5w6fw6q 2273 11 recurrent recurrent JJ cord-006870-f5w6fw6q 2273 12 or or CC cord-006870-f5w6fw6q 2273 13 progressive progressive JJ cord-006870-f5w6fw6q 2273 14 ) ) -RRB- cord-006870-f5w6fw6q 2273 15 strokes stroke NNS cord-006870-f5w6fw6q 2273 16 with with IN cord-006870-f5w6fw6q 2273 17 clinical clinical JJ cord-006870-f5w6fw6q 2273 18 , , , cord-006870-f5w6fw6q 2273 19 CSF CSF NNP cord-006870-f5w6fw6q 2273 20 and and CC cord-006870-f5w6fw6q 2273 21 MRI MRI NNP cord-006870-f5w6fw6q 2273 22 features feature VBZ cord-006870-f5w6fw6q 2273 23 described describe VBN cord-006870-f5w6fw6q 2273 24 . . . cord-006870-f5w6fw6q 2274 1 Life life NN cord-006870-f5w6fw6q 2274 2 - - HYPH cord-006870-f5w6fw6q 2274 3 threatening threaten VBG cord-006870-f5w6fw6q 2274 4 bleeding bleeding NN cord-006870-f5w6fw6q 2274 5 requires require VBZ cord-006870-f5w6fw6q 2274 6 prompt prompt JJ cord-006870-f5w6fw6q 2274 7 reversal reversal NN cord-006870-f5w6fw6q 2274 8 of of IN cord-006870-f5w6fw6q 2274 9 factor factor NN cord-006870-f5w6fw6q 2274 10 Xa Xa NNP cord-006870-f5w6fw6q 2274 11 ( ( -LRB- cord-006870-f5w6fw6q 2274 12 FXa FXa NNPS cord-006870-f5w6fw6q 2274 13 ) ) -RRB- cord-006870-f5w6fw6q 2274 14 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2274 15 . . . cord-006870-f5w6fw6q 2275 1 Their -PRON- PRP$ cord-006870-f5w6fw6q 2275 2 anticoagulant anticoagulant JJ cord-006870-f5w6fw6q 2275 3 effects effect NNS cord-006870-f5w6fw6q 2275 4 can can MD cord-006870-f5w6fw6q 2275 5 be be VB cord-006870-f5w6fw6q 2275 6 reversed reverse VBN cord-006870-f5w6fw6q 2275 7 with with IN cord-006870-f5w6fw6q 2275 8 the the DT cord-006870-f5w6fw6q 2275 9 antidote antidote NN cord-006870-f5w6fw6q 2275 10 andexanet andexanet NNP cord-006870-f5w6fw6q 2275 11 alfa alfa NNP cord-006870-f5w6fw6q 2275 12 . . . cord-006870-f5w6fw6q 2276 1 The the DT cord-006870-f5w6fw6q 2276 2 efficacy efficacy NN cord-006870-f5w6fw6q 2276 3 of of IN cord-006870-f5w6fw6q 2276 4 andexanet andexanet NN cord-006870-f5w6fw6q 2276 5 to to TO cord-006870-f5w6fw6q 2276 6 reverse reverse VB cord-006870-f5w6fw6q 2276 7 bleeding bleeding NN cord-006870-f5w6fw6q 2276 8 in in IN cord-006870-f5w6fw6q 2276 9 an an DT cord-006870-f5w6fw6q 2276 10 apixaban apixaban NNP cord-006870-f5w6fw6q 2276 11 anticoagulated anticoagulate VBN cord-006870-f5w6fw6q 2276 12 porcine porcine JJ cord-006870-f5w6fw6q 2276 13 trauma trauma NN cord-006870-f5w6fw6q 2276 14 model model NN cord-006870-f5w6fw6q 2276 15 was be VBD cord-006870-f5w6fw6q 2276 16 investigated investigate VBN cord-006870-f5w6fw6q 2276 17 . . . cord-006870-f5w6fw6q 2277 1 After after IN cord-006870-f5w6fw6q 2277 2 ethical ethical JJ cord-006870-f5w6fw6q 2277 3 approval approval NN cord-006870-f5w6fw6q 2277 4 , , , cord-006870-f5w6fw6q 2277 5 male male JJ cord-006870-f5w6fw6q 2277 6 pigs pig NNS cord-006870-f5w6fw6q 2277 7 ( ( -LRB- cord-006870-f5w6fw6q 2277 8 n=15 n=15 NNP cord-006870-f5w6fw6q 2277 9 ) ) -RRB- cord-006870-f5w6fw6q 2277 10 were be VBD cord-006870-f5w6fw6q 2277 11 given give VBN cord-006870-f5w6fw6q 2277 12 apixaban apixaban NNP cord-006870-f5w6fw6q 2277 13 for for IN cord-006870-f5w6fw6q 2277 14 3 3 CD cord-006870-f5w6fw6q 2277 15 days day NNS cord-006870-f5w6fw6q 2277 16 ( ( -LRB- cord-006870-f5w6fw6q 2277 17 20 20 CD cord-006870-f5w6fw6q 2277 18 mg mg NNP cord-006870-f5w6fw6q 2277 19 daily daily RB cord-006870-f5w6fw6q 2277 20 ) ) -RRB- cord-006870-f5w6fw6q 2277 21 ; ; : cord-006870-f5w6fw6q 2277 22 the the DT cord-006870-f5w6fw6q 2277 23 sham sham NN cord-006870-f5w6fw6q 2277 24 group group NN cord-006870-f5w6fw6q 2277 25 ( ( -LRB- cord-006870-f5w6fw6q 2277 26 n=5 n=5 NNP cord-006870-f5w6fw6q 2277 27 ) ) -RRB- cord-006870-f5w6fw6q 2277 28 received receive VBD cord-006870-f5w6fw6q 2277 29 placebo placebo NN cord-006870-f5w6fw6q 2277 30 . . . cord-006870-f5w6fw6q 2278 1 Standardized standardized JJ cord-006870-f5w6fw6q 2278 2 polytrauma polytrauma NN cord-006870-f5w6fw6q 2278 3 by by IN cord-006870-f5w6fw6q 2278 4 blunt blunt JJ cord-006870-f5w6fw6q 2278 5 liver liver NN cord-006870-f5w6fw6q 2278 6 injury injury NN cord-006870-f5w6fw6q 2278 7 and and CC cord-006870-f5w6fw6q 2278 8 bilateral bilateral JJ cord-006870-f5w6fw6q 2278 9 femur femur NN cord-006870-f5w6fw6q 2278 10 fractures fracture NNS cord-006870-f5w6fw6q 2278 11 were be VBD cord-006870-f5w6fw6q 2278 12 inflicted inflict VBN cord-006870-f5w6fw6q 2278 13 . . . cord-006870-f5w6fw6q 2279 1 12 12 CD cord-006870-f5w6fw6q 2279 2 minutes minute NNS cord-006870-f5w6fw6q 2279 3 post post NN cord-006870-f5w6fw6q 2279 4 - - NN cord-006870-f5w6fw6q 2279 5 trauma trauma NN cord-006870-f5w6fw6q 2279 6 , , , cord-006870-f5w6fw6q 2279 7 animals animal NNS cord-006870-f5w6fw6q 2279 8 were be VBD cord-006870-f5w6fw6q 2279 9 randomized randomize VBN cord-006870-f5w6fw6q 2279 10 ( ( -LRB- cord-006870-f5w6fw6q 2279 11 n=5 n=5 JJ cord-006870-f5w6fw6q 2279 12 per per IN cord-006870-f5w6fw6q 2279 13 group group NN cord-006870-f5w6fw6q 2279 14 ) ) -RRB- cord-006870-f5w6fw6q 2279 15 to to IN cord-006870-f5w6fw6q 2279 16 a a DT cord-006870-f5w6fw6q 2279 17 single single JJ cord-006870-f5w6fw6q 2279 18 andexanet andexanet NN cord-006870-f5w6fw6q 2279 19 bolus bolus NN cord-006870-f5w6fw6q 2279 20 ( ( -LRB- cord-006870-f5w6fw6q 2279 21 1,000 1,000 CD cord-006870-f5w6fw6q 2279 22 mg mg NNP cord-006870-f5w6fw6q 2279 23 ) ) -RRB- cord-006870-f5w6fw6q 2279 24 , , , cord-006870-f5w6fw6q 2279 25 a a DT cord-006870-f5w6fw6q 2279 26 bolus bolus NN cord-006870-f5w6fw6q 2279 27 ( ( -LRB- cord-006870-f5w6fw6q 2279 28 1,000 1,000 CD cord-006870-f5w6fw6q 2279 29 mg mg NNP cord-006870-f5w6fw6q 2279 30 ) ) -RRB- cord-006870-f5w6fw6q 2279 31 + + CC cord-006870-f5w6fw6q 2279 32 infusion infusion NN cord-006870-f5w6fw6q 2279 33 ( ( -LRB- cord-006870-f5w6fw6q 2279 34 1,200 1,200 CD cord-006870-f5w6fw6q 2279 35 mg mg NN cord-006870-f5w6fw6q 2279 36 over over IN cord-006870-f5w6fw6q 2279 37 2 2 CD cord-006870-f5w6fw6q 2279 38 hours hour NNS cord-006870-f5w6fw6q 2279 39 ) ) -RRB- cord-006870-f5w6fw6q 2279 40 regimen regimen NN cord-006870-f5w6fw6q 2279 41 , , , cord-006870-f5w6fw6q 2279 42 or or CC cord-006870-f5w6fw6q 2279 43 vehicle vehicle NN cord-006870-f5w6fw6q 2279 44 ( ( -LRB- cord-006870-f5w6fw6q 2279 45 control control NN cord-006870-f5w6fw6q 2279 46 ) ) -RRB- cord-006870-f5w6fw6q 2279 47 . . . cord-006870-f5w6fw6q 2280 1 Blood blood NN cord-006870-f5w6fw6q 2280 2 loss loss NN cord-006870-f5w6fw6q 2280 3 ( ( -LRB- cord-006870-f5w6fw6q 2280 4 BL BL NNP cord-006870-f5w6fw6q 2280 5 ) ) -RRB- cord-006870-f5w6fw6q 2280 6 and and CC cord-006870-f5w6fw6q 2280 7 hemodynamics hemodynamic NNS cord-006870-f5w6fw6q 2280 8 were be VBD cord-006870-f5w6fw6q 2280 9 monitored monitor VBN cord-006870-f5w6fw6q 2280 10 over over IN cord-006870-f5w6fw6q 2280 11 6 6 CD cord-006870-f5w6fw6q 2280 12 hours hour NNS cord-006870-f5w6fw6q 2280 13 or or CC cord-006870-f5w6fw6q 2280 14 until until IN cord-006870-f5w6fw6q 2280 15 death death NN cord-006870-f5w6fw6q 2280 16 and and CC cord-006870-f5w6fw6q 2280 17 analyzed analyze VBN cord-006870-f5w6fw6q 2280 18 by by IN cord-006870-f5w6fw6q 2280 19 ANOVA ANOVA NNP cord-006870-f5w6fw6q 2280 20 ( ( -LRB- cord-006870-f5w6fw6q 2280 21 mean±SEM mean±SEM NNS cord-006870-f5w6fw6q 2280 22 ) ) -RRB- cord-006870-f5w6fw6q 2280 23 . . . cord-006870-f5w6fw6q 2281 1 Apixaban Apixaban NNP cord-006870-f5w6fw6q 2281 2 anti anti JJ cord-006870-f5w6fw6q 2281 3 - - JJ cord-006870-f5w6fw6q 2281 4 FXa fxa JJ cord-006870-f5w6fw6q 2281 5 levels level NNS cord-006870-f5w6fw6q 2281 6 were be VBD cord-006870-f5w6fw6q 2281 7 183±26 183±26 CD cord-006870-f5w6fw6q 2281 8 ng ng NN cord-006870-f5w6fw6q 2281 9 / / SYM cord-006870-f5w6fw6q 2281 10 mL ml XX cord-006870-f5w6fw6q 2281 11 with with IN cord-006870-f5w6fw6q 2281 12 no no DT cord-006870-f5w6fw6q 2281 13 differences difference NNS cord-006870-f5w6fw6q 2281 14 between between IN cord-006870-f5w6fw6q 2281 15 anticoagulated anticoagulated JJ cord-006870-f5w6fw6q 2281 16 groups group NNS cord-006870-f5w6fw6q 2281 17 prior prior RB cord-006870-f5w6fw6q 2281 18 to to IN cord-006870-f5w6fw6q 2281 19 injury injury NN cord-006870-f5w6fw6q 2281 20 . . . cord-006870-f5w6fw6q 2282 1 BL BL NNP cord-006870-f5w6fw6q 2282 2 in in IN cord-006870-f5w6fw6q 2282 3 the the DT cord-006870-f5w6fw6q 2282 4 sham sham NN cord-006870-f5w6fw6q 2282 5 animals animal NNS cord-006870-f5w6fw6q 2282 6 was be VBD cord-006870-f5w6fw6q 2282 7 494 494 CD cord-006870-f5w6fw6q 2282 8 ± ± CD cord-006870-f5w6fw6q 2282 9 24 24 CD cord-006870-f5w6fw6q 2282 10 mL ml NN cord-006870-f5w6fw6q 2282 11 12 12 CD cord-006870-f5w6fw6q 2282 12 minutes minute NNS cord-006870-f5w6fw6q 2282 13 after after IN cord-006870-f5w6fw6q 2282 14 injury injury NN cord-006870-f5w6fw6q 2283 1 ( ( -LRB- cord-006870-f5w6fw6q 2283 2 total total JJ cord-006870-f5w6fw6q 2283 3 BL BL NNP cord-006870-f5w6fw6q 2283 4 651±39 651±39 CD cord-006870-f5w6fw6q 2283 5 mL ml NN cord-006870-f5w6fw6q 2283 6 at at IN cord-006870-f5w6fw6q 2283 7 " " `` cord-006870-f5w6fw6q 2283 8 x x SYM cord-006870-f5w6fw6q 2283 9 " " '' cord-006870-f5w6fw6q 2283 10 hours hour NNS cord-006870-f5w6fw6q 2283 11 ; ; : cord-006870-f5w6fw6q 2283 12 100 100 CD cord-006870-f5w6fw6q 2283 13 % % NN cord-006870-f5w6fw6q 2283 14 survival survival NN cord-006870-f5w6fw6q 2283 15 ) ) -RRB- cord-006870-f5w6fw6q 2283 16 . . . cord-006870-f5w6fw6q 2284 1 Anticoagulation Anticoagulation NNP cord-006870-f5w6fw6q 2284 2 with with IN cord-006870-f5w6fw6q 2284 3 apixaban apixaban NNP cord-006870-f5w6fw6q 2284 4 significantly significantly RB cord-006870-f5w6fw6q 2284 5 increased increase VBD cord-006870-f5w6fw6q 2284 6 BL BL NNP cord-006870-f5w6fw6q 2284 7 12 12 CD cord-006870-f5w6fw6q 2284 8 minutes minute NNS cord-006870-f5w6fw6q 2284 9 after after IN cord-006870-f5w6fw6q 2284 10 injury injury NN cord-006870-f5w6fw6q 2284 11 ( ( -LRB- cord-006870-f5w6fw6q 2284 12 873±25 873±25 CD cord-006870-f5w6fw6q 2284 13 mL ml NN cord-006870-f5w6fw6q 2284 14 ; ; : cord-006870-f5w6fw6q 2284 15 P<0.01 P<0.01 NNP cord-006870-f5w6fw6q 2284 16 ) ) -RRB- cord-006870-f5w6fw6q 2284 17 . . . cord-006870-f5w6fw6q 2285 1 Controls control NNS cord-006870-f5w6fw6q 2285 2 exhibited exhibit VBD cord-006870-f5w6fw6q 2285 3 a a DT cord-006870-f5w6fw6q 2285 4 total total JJ cord-006870-f5w6fw6q 2285 5 BL bl NN cord-006870-f5w6fw6q 2285 6 of of IN cord-006870-f5w6fw6q 2285 7 3,913±235 3,913±235 CD cord-006870-f5w6fw6q 2285 8 mL ml NN cord-006870-f5w6fw6q 2285 9 with with IN cord-006870-f5w6fw6q 2285 10 100 100 CD cord-006870-f5w6fw6q 2285 11 % % NN cord-006870-f5w6fw6q 2285 12 mortality mortality NN cord-006870-f5w6fw6q 2285 13 ( ( -LRB- cord-006870-f5w6fw6q 2285 14 mean mean JJ cord-006870-f5w6fw6q 2285 15 survival survival NN cord-006870-f5w6fw6q 2285 16 time time NN cord-006870-f5w6fw6q 2285 17 = = SYM cord-006870-f5w6fw6q 2285 18 165 165 CD cord-006870-f5w6fw6q 2285 19 minutes minute NNS cord-006870-f5w6fw6q 2285 20 ) ) -RRB- cord-006870-f5w6fw6q 2285 21 . . . cord-006870-f5w6fw6q 2286 1 Treatment treatment NN cord-006870-f5w6fw6q 2286 2 with with IN cord-006870-f5w6fw6q 2286 3 a a DT cord-006870-f5w6fw6q 2286 4 bolus bolus NN cord-006870-f5w6fw6q 2286 5 or or CC cord-006870-f5w6fw6q 2286 6 bolus+infusion bolus+infusion NN cord-006870-f5w6fw6q 2286 7 of of IN cord-006870-f5w6fw6q 2286 8 andexanet andexanet NNP cord-006870-f5w6fw6q 2286 9 was be VBD cord-006870-f5w6fw6q 2286 10 associated associate VBN cord-006870-f5w6fw6q 2286 11 with with IN cord-006870-f5w6fw6q 2286 12 a a DT cord-006870-f5w6fw6q 2286 13 significant significant JJ cord-006870-f5w6fw6q 2286 14 reduction reduction NN cord-006870-f5w6fw6q 2286 15 in in IN cord-006870-f5w6fw6q 2286 16 BL BL NNP cord-006870-f5w6fw6q 2286 17 versus versus IN cord-006870-f5w6fw6q 2286 18 sham sham JJ cord-006870-f5w6fw6q 2286 19 ( ( -LRB- cord-006870-f5w6fw6q 2286 20 P<0.05 P<0.05 NNP cord-006870-f5w6fw6q 2286 21 ) ) -RRB- cord-006870-f5w6fw6q 2286 22 and and CC cord-006870-f5w6fw6q 2286 23 100 100 CD cord-006870-f5w6fw6q 2286 24 % % NN cord-006870-f5w6fw6q 2286 25 survival survival NN cord-006870-f5w6fw6q 2286 26 . . . cord-006870-f5w6fw6q 2287 1 Two two CD cord-006870-f5w6fw6q 2287 2 hours hour NNS cord-006870-f5w6fw6q 2287 3 after after IN cord-006870-f5w6fw6q 2287 4 injury injury NN cord-006870-f5w6fw6q 2287 5 , , , cord-006870-f5w6fw6q 2287 6 apixaban apixaban NNP cord-006870-f5w6fw6q 2287 7 anti anti JJ cord-006870-f5w6fw6q 2287 8 - - JJ cord-006870-f5w6fw6q 2287 9 FXa fxa JJ cord-006870-f5w6fw6q 2287 10 levels level NNS cord-006870-f5w6fw6q 2287 11 in in IN cord-006870-f5w6fw6q 2287 12 bolus bolus NN cord-006870-f5w6fw6q 2287 13 animals animal NNS cord-006870-f5w6fw6q 2287 14 were be VBD cord-006870-f5w6fw6q 2287 15 99±45 99±45 NNP cord-006870-f5w6fw6q 2287 16 ng ng NN cord-006870-f5w6fw6q 2287 17 / / SYM cord-006870-f5w6fw6q 2287 18 mL mL NNP cord-006870-f5w6fw6q 2287 19 , , , cord-006870-f5w6fw6q 2287 20 whereas whereas IN cord-006870-f5w6fw6q 2287 21 the the DT cord-006870-f5w6fw6q 2287 22 bolus+infusion bolus+infusion NNP cord-006870-f5w6fw6q 2287 23 regimen regimen NN cord-006870-f5w6fw6q 2287 24 resulted result VBD cord-006870-f5w6fw6q 2287 25 in in IN cord-006870-f5w6fw6q 2287 26 levels level NNS cord-006870-f5w6fw6q 2287 27 of of IN cord-006870-f5w6fw6q 2287 28 17±6 17±6 CD cord-006870-f5w6fw6q 2287 29 ng ng NN cord-006870-f5w6fw6q 2287 30 / / SYM cord-006870-f5w6fw6q 2287 31 mL ml NN cord-006870-f5w6fw6q 2287 32 ( ( -LRB- cord-006870-f5w6fw6q 2287 33 P<0.05 P<0.05 NNS cord-006870-f5w6fw6q 2287 34 ) ) -RRB- cord-006870-f5w6fw6q 2287 35 . . . cord-006870-f5w6fw6q 2288 1 Hemodynamic Hemodynamic NNP cord-006870-f5w6fw6q 2288 2 parameters parameter NNS cord-006870-f5w6fw6q 2288 3 ( ( -LRB- cord-006870-f5w6fw6q 2288 4 e.g. e.g. RB cord-006870-f5w6fw6q 2288 5 , , , cord-006870-f5w6fw6q 2288 6 cardiac cardiac JJ cord-006870-f5w6fw6q 2288 7 output output NN cord-006870-f5w6fw6q 2288 8 ) ) -RRB- cord-006870-f5w6fw6q 2288 9 and and CC cord-006870-f5w6fw6q 2288 10 markers marker NNS cord-006870-f5w6fw6q 2288 11 of of IN cord-006870-f5w6fw6q 2288 12 shock shock NN cord-006870-f5w6fw6q 2288 13 ( ( -LRB- cord-006870-f5w6fw6q 2288 14 e.g. e.g. RB cord-006870-f5w6fw6q 2288 15 , , , cord-006870-f5w6fw6q 2288 16 lactate lactate NN cord-006870-f5w6fw6q 2288 17 ) ) -RRB- cord-006870-f5w6fw6q 2288 18 recovered recover VBD cord-006870-f5w6fw6q 2288 19 to to TO cord-006870-f5w6fw6q 2288 20 pre pre VB cord-006870-f5w6fw6q 2288 21 - - JJ cord-006870-f5w6fw6q 2288 22 trauma trauma JJ cord-006870-f5w6fw6q 2288 23 levels level NNS cord-006870-f5w6fw6q 2288 24 in in IN cord-006870-f5w6fw6q 2288 25 andexanet andexanet NN cord-006870-f5w6fw6q 2288 26 - - HYPH cord-006870-f5w6fw6q 2288 27 treated treat VBN cord-006870-f5w6fw6q 2288 28 groups group NNS cord-006870-f5w6fw6q 2288 29 . . . cord-006870-f5w6fw6q 2289 1 Clinically clinically RB cord-006870-f5w6fw6q 2289 2 and and CC cord-006870-f5w6fw6q 2289 3 macroscopically macroscopically RB cord-006870-f5w6fw6q 2289 4 , , , cord-006870-f5w6fw6q 2289 5 no no DT cord-006870-f5w6fw6q 2289 6 adverse adverse JJ cord-006870-f5w6fw6q 2289 7 events event NNS cord-006870-f5w6fw6q 2289 8 were be VBD cord-006870-f5w6fw6q 2289 9 observed observe VBN cord-006870-f5w6fw6q 2289 10 . . . cord-006870-f5w6fw6q 2290 1 In in IN cord-006870-f5w6fw6q 2290 2 this this DT cord-006870-f5w6fw6q 2290 3 study study NN cord-006870-f5w6fw6q 2290 4 , , , cord-006870-f5w6fw6q 2290 5 andexanet andexanet VBZ cord-006870-f5w6fw6q 2290 6 effectively effectively RB cord-006870-f5w6fw6q 2290 7 and and CC cord-006870-f5w6fw6q 2290 8 safely safely RB cord-006870-f5w6fw6q 2290 9 reversed reverse VBD cord-006870-f5w6fw6q 2290 10 apixaban apixaban NNP cord-006870-f5w6fw6q 2290 11 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2290 12 and and CC cord-006870-f5w6fw6q 2290 13 reduced reduce VBN cord-006870-f5w6fw6q 2290 14 BL BL NNP cord-006870-f5w6fw6q 2290 15 induced induce VBN cord-006870-f5w6fw6q 2290 16 by by IN cord-006870-f5w6fw6q 2290 17 severe severe JJ cord-006870-f5w6fw6q 2290 18 trauma trauma NN cord-006870-f5w6fw6q 2290 19 under under IN cord-006870-f5w6fw6q 2290 20 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2290 21 . . . cord-006870-f5w6fw6q 2291 1 The the DT cord-006870-f5w6fw6q 2291 2 bolus bolus NN cord-006870-f5w6fw6q 2291 3 alone alone RB cord-006870-f5w6fw6q 2291 4 had have VBD cord-006870-f5w6fw6q 2291 5 a a DT cord-006870-f5w6fw6q 2291 6 similar similar JJ cord-006870-f5w6fw6q 2291 7 impact impact NN cord-006870-f5w6fw6q 2291 8 on on IN cord-006870-f5w6fw6q 2291 9 survival survival NN cord-006870-f5w6fw6q 2291 10 and and CC cord-006870-f5w6fw6q 2291 11 BL BL NNP cord-006870-f5w6fw6q 2291 12 as as IN cord-006870-f5w6fw6q 2291 13 the the DT cord-006870-f5w6fw6q 2291 14 bolus+infusion bolus+infusion NNP cord-006870-f5w6fw6q 2291 15 regimen regimen NN cord-006870-f5w6fw6q 2291 16 in in IN cord-006870-f5w6fw6q 2291 17 this this DT cord-006870-f5w6fw6q 2291 18 lethal lethal JJ cord-006870-f5w6fw6q 2291 19 porcine porcine JJ cord-006870-f5w6fw6q 2291 20 model model NN cord-006870-f5w6fw6q 2291 21 . . . cord-006870-f5w6fw6q 2292 1 Current current JJ cord-006870-f5w6fw6q 2292 2 guidelines guideline NNS cord-006870-f5w6fw6q 2292 3 for for IN cord-006870-f5w6fw6q 2292 4 management management NN cord-006870-f5w6fw6q 2292 5 of of IN cord-006870-f5w6fw6q 2292 6 pain pain NN cord-006870-f5w6fw6q 2292 7 , , , cord-006870-f5w6fw6q 2292 8 agitation agitation NN cord-006870-f5w6fw6q 2292 9 , , , cord-006870-f5w6fw6q 2292 10 and and CC cord-006870-f5w6fw6q 2292 11 delirium delirium NN cord-006870-f5w6fw6q 2292 12 in in IN cord-006870-f5w6fw6q 2292 13 mechanically mechanically RB cord-006870-f5w6fw6q 2292 14 ventilated ventilate VBN cord-006870-f5w6fw6q 2292 15 patients patient NNS cord-006870-f5w6fw6q 2292 16 in in IN cord-006870-f5w6fw6q 2292 17 the the DT cord-006870-f5w6fw6q 2292 18 intensive intensive JJ cord-006870-f5w6fw6q 2292 19 care care NN cord-006870-f5w6fw6q 2292 20 unit unit NN cord-006870-f5w6fw6q 2292 21 ( ( -LRB- cord-006870-f5w6fw6q 2292 22 ICU ICU NNP cord-006870-f5w6fw6q 2292 23 ) ) -RRB- cord-006870-f5w6fw6q 2292 24 recommend recommend VBP cord-006870-f5w6fw6q 2292 25 an an DT cord-006870-f5w6fw6q 2292 26 analgesia analgesia NN cord-006870-f5w6fw6q 2292 27 - - HYPH cord-006870-f5w6fw6q 2292 28 first first JJ cord-006870-f5w6fw6q 2292 29 approach approach NN cord-006870-f5w6fw6q 2292 30 to to IN cord-006870-f5w6fw6q 2292 31 sedation sedation NN cord-006870-f5w6fw6q 2292 32 management management NN cord-006870-f5w6fw6q 2292 33 . . . cord-006870-f5w6fw6q 2293 1 However however RB cord-006870-f5w6fw6q 2293 2 , , , cord-006870-f5w6fw6q 2293 3 these these DT cord-006870-f5w6fw6q 2293 4 guidelines guideline NNS cord-006870-f5w6fw6q 2293 5 are be VBP cord-006870-f5w6fw6q 2293 6 derived derive VBN cord-006870-f5w6fw6q 2293 7 from from IN cord-006870-f5w6fw6q 2293 8 non non JJ cord-006870-f5w6fw6q 2293 9 - - JJ cord-006870-f5w6fw6q 2293 10 neurologic neurologic JJ cord-006870-f5w6fw6q 2293 11 patient patient JJ cord-006870-f5w6fw6q 2293 12 populations population NNS cord-006870-f5w6fw6q 2293 13 leaving leave VBG cord-006870-f5w6fw6q 2293 14 uncertainty uncertainty NN cord-006870-f5w6fw6q 2293 15 in in IN cord-006870-f5w6fw6q 2293 16 their -PRON- PRP$ cord-006870-f5w6fw6q 2293 17 generalization generalization NN cord-006870-f5w6fw6q 2293 18 to to IN cord-006870-f5w6fw6q 2293 19 this this DT cord-006870-f5w6fw6q 2293 20 population population NN cord-006870-f5w6fw6q 2293 21 . . . cord-006870-f5w6fw6q 2294 1 The the DT cord-006870-f5w6fw6q 2294 2 purpose purpose NN cord-006870-f5w6fw6q 2294 3 of of IN cord-006870-f5w6fw6q 2294 4 this this DT cord-006870-f5w6fw6q 2294 5 study study NN cord-006870-f5w6fw6q 2294 6 was be VBD cord-006870-f5w6fw6q 2294 7 to to TO cord-006870-f5w6fw6q 2294 8 evaluate evaluate VB cord-006870-f5w6fw6q 2294 9 implementation implementation NN cord-006870-f5w6fw6q 2294 10 of of IN cord-006870-f5w6fw6q 2294 11 an an DT cord-006870-f5w6fw6q 2294 12 analgesia analgesia NN cord-006870-f5w6fw6q 2294 13 - - HYPH cord-006870-f5w6fw6q 2294 14 first first JJ cord-006870-f5w6fw6q 2294 15 sedation sedation NN cord-006870-f5w6fw6q 2294 16 clinical clinical JJ cord-006870-f5w6fw6q 2294 17 pathway pathway NN cord-006870-f5w6fw6q 2294 18 in in IN cord-006870-f5w6fw6q 2294 19 the the DT cord-006870-f5w6fw6q 2294 20 neuroscience neuroscience NN cord-006870-f5w6fw6q 2294 21 ICU ICU NNP cord-006870-f5w6fw6q 2294 22 . . . cord-006870-f5w6fw6q 2295 1 A a DT cord-006870-f5w6fw6q 2295 2 single single JJ cord-006870-f5w6fw6q 2295 3 - - HYPH cord-006870-f5w6fw6q 2295 4 center center NN cord-006870-f5w6fw6q 2295 5 cohort cohort NN cord-006870-f5w6fw6q 2295 6 study study NN cord-006870-f5w6fw6q 2295 7 was be VBD cord-006870-f5w6fw6q 2295 8 performed perform VBN cord-006870-f5w6fw6q 2295 9 within within IN cord-006870-f5w6fw6q 2295 10 the the DT cord-006870-f5w6fw6q 2295 11 neuroscience neuroscience NN cord-006870-f5w6fw6q 2295 12 ICU ICU NNP cord-006870-f5w6fw6q 2295 13 including include VBG cord-006870-f5w6fw6q 2295 14 patients patient NNS cord-006870-f5w6fw6q 2295 15 mechanically mechanically RB cord-006870-f5w6fw6q 2295 16 ventilated ventilate VBN cord-006870-f5w6fw6q 2295 17 for for IN cord-006870-f5w6fw6q 2295 18 greater great JJR cord-006870-f5w6fw6q 2295 19 than than IN cord-006870-f5w6fw6q 2295 20 48 48 CD cord-006870-f5w6fw6q 2295 21 hours hour NNS cord-006870-f5w6fw6q 2295 22 over over IN cord-006870-f5w6fw6q 2295 23 a a DT cord-006870-f5w6fw6q 2295 24 time time NN cord-006870-f5w6fw6q 2295 25 period period NN cord-006870-f5w6fw6q 2295 26 of of IN cord-006870-f5w6fw6q 2295 27 three three CD cord-006870-f5w6fw6q 2295 28 months month NNS cord-006870-f5w6fw6q 2295 29 before before IN cord-006870-f5w6fw6q 2295 30 and and CC cord-006870-f5w6fw6q 2295 31 after after IN cord-006870-f5w6fw6q 2295 32 clinical clinical JJ cord-006870-f5w6fw6q 2295 33 pathway pathway NN cord-006870-f5w6fw6q 2295 34 implementation implementation NN cord-006870-f5w6fw6q 2295 35 . . . cord-006870-f5w6fw6q 2296 1 Providers provider NNS cord-006870-f5w6fw6q 2296 2 were be VBD cord-006870-f5w6fw6q 2296 3 educated educate VBN cord-006870-f5w6fw6q 2296 4 on on IN cord-006870-f5w6fw6q 2296 5 the the DT cord-006870-f5w6fw6q 2296 6 pathway pathway NN cord-006870-f5w6fw6q 2296 7 with with IN cord-006870-f5w6fw6q 2296 8 emphasis emphasis NN cord-006870-f5w6fw6q 2296 9 on on IN cord-006870-f5w6fw6q 2296 10 frequent frequent JJ cord-006870-f5w6fw6q 2296 11 assessment assessment NN cord-006870-f5w6fw6q 2296 12 of of IN cord-006870-f5w6fw6q 2296 13 Richmond Richmond NNP cord-006870-f5w6fw6q 2296 14 Agitation Agitation NNP cord-006870-f5w6fw6q 2296 15 - - HYPH cord-006870-f5w6fw6q 2296 16 Sedation sedation NN cord-006870-f5w6fw6q 2296 17 Scales scale NNS cord-006870-f5w6fw6q 2296 18 ( ( -LRB- cord-006870-f5w6fw6q 2296 19 RASS RASS NNP cord-006870-f5w6fw6q 2296 20 ) ) -RRB- cord-006870-f5w6fw6q 2296 21 , , , cord-006870-f5w6fw6q 2296 22 Critical Critical NNP cord-006870-f5w6fw6q 2296 23 Care Care NNP cord-006870-f5w6fw6q 2296 24 Pain pain NN cord-006870-f5w6fw6q 2296 25 Observation observation NN cord-006870-f5w6fw6q 2296 26 Tool tool NN cord-006870-f5w6fw6q 2296 27 ( ( -LRB- cord-006870-f5w6fw6q 2296 28 CPOT CPOT NNP cord-006870-f5w6fw6q 2296 29 ) ) -RRB- cord-006870-f5w6fw6q 2296 30 , , , cord-006870-f5w6fw6q 2296 31 and and CC cord-006870-f5w6fw6q 2296 32 Confusion Confusion NNP cord-006870-f5w6fw6q 2296 33 Assessment Assessment NNP cord-006870-f5w6fw6q 2296 34 Method Method NNP cord-006870-f5w6fw6q 2296 35 - - HYPH cord-006870-f5w6fw6q 2296 36 ICU ICU NNP cord-006870-f5w6fw6q 2296 37 ( ( -LRB- cord-006870-f5w6fw6q 2296 38 CAM CAM NNP cord-006870-f5w6fw6q 2296 39 - - HYPH cord-006870-f5w6fw6q 2296 40 ICU ICU NNP cord-006870-f5w6fw6q 2296 41 ) ) -RRB- cord-006870-f5w6fw6q 2296 42 scores score NNS cord-006870-f5w6fw6q 2296 43 and and CC cord-006870-f5w6fw6q 2296 44 systematic systematic JJ cord-006870-f5w6fw6q 2296 45 de de NN cord-006870-f5w6fw6q 2296 46 - - NN cord-006870-f5w6fw6q 2296 47 escalation escalation NN cord-006870-f5w6fw6q 2296 48 of of IN cord-006870-f5w6fw6q 2296 49 sedatives sedative NNS cord-006870-f5w6fw6q 2296 50 through through IN cord-006870-f5w6fw6q 2296 51 adequate adequate JJ cord-006870-f5w6fw6q 2296 52 pain pain NN cord-006870-f5w6fw6q 2296 53 and and CC cord-006870-f5w6fw6q 2296 54 delirium delirium NN cord-006870-f5w6fw6q 2296 55 management management NN cord-006870-f5w6fw6q 2296 56 . . . cord-006870-f5w6fw6q 2297 1 Outcome outcome NN cord-006870-f5w6fw6q 2297 2 measures measure NNS cord-006870-f5w6fw6q 2297 3 included include VBD cord-006870-f5w6fw6q 2297 4 frequency frequency NN cord-006870-f5w6fw6q 2297 5 and and CC cord-006870-f5w6fw6q 2297 6 magnitude magnitude NN cord-006870-f5w6fw6q 2297 7 of of IN cord-006870-f5w6fw6q 2297 8 RASS RASS NNP cord-006870-f5w6fw6q 2297 9 , , , cord-006870-f5w6fw6q 2297 10 CPOT CPOT NNP cord-006870-f5w6fw6q 2297 11 , , , cord-006870-f5w6fw6q 2297 12 and and CC cord-006870-f5w6fw6q 2297 13 CAM CAM NNP cord-006870-f5w6fw6q 2297 14 - - HYPH cord-006870-f5w6fw6q 2297 15 ICU ICU NNP cord-006870-f5w6fw6q 2297 16 scores score NNS cord-006870-f5w6fw6q 2297 17 , , , cord-006870-f5w6fw6q 2297 18 analgesic analgesic JJ cord-006870-f5w6fw6q 2297 19 and and CC cord-006870-f5w6fw6q 2297 20 sedative sedative JJ cord-006870-f5w6fw6q 2297 21 medication medication NN cord-006870-f5w6fw6q 2297 22 prescription prescription NN cord-006870-f5w6fw6q 2297 23 / / SYM cord-006870-f5w6fw6q 2297 24 administration administration NN cord-006870-f5w6fw6q 2297 25 per per IN cord-006870-f5w6fw6q 2297 26 day day NN cord-006870-f5w6fw6q 2297 27 of of IN cord-006870-f5w6fw6q 2297 28 mechanical mechanical JJ cord-006870-f5w6fw6q 2297 29 ventilation ventilation NN cord-006870-f5w6fw6q 2297 30 ( ( -LRB- cord-006870-f5w6fw6q 2297 31 MV MV NNP cord-006870-f5w6fw6q 2297 32 ) ) -RRB- cord-006870-f5w6fw6q 2297 33 . . . cord-006870-f5w6fw6q 2298 1 A a DT cord-006870-f5w6fw6q 2298 2 total total NN cord-006870-f5w6fw6q 2298 3 of of IN cord-006870-f5w6fw6q 2298 4 107 107 CD cord-006870-f5w6fw6q 2298 5 patients patient NNS cord-006870-f5w6fw6q 2298 6 met meet VBD cord-006870-f5w6fw6q 2298 7 inclusion inclusion NN cord-006870-f5w6fw6q 2298 8 criteria criterion NNS cord-006870-f5w6fw6q 2298 9 ( ( -LRB- cord-006870-f5w6fw6q 2298 10 67 67 CD cord-006870-f5w6fw6q 2298 11 pre pre JJ cord-006870-f5w6fw6q 2298 12 - - JJ cord-006870-f5w6fw6q 2298 13 pathway pathway JJ cord-006870-f5w6fw6q 2298 14 and and CC cord-006870-f5w6fw6q 2298 15 40 40 CD cord-006870-f5w6fw6q 2298 16 post post JJ cord-006870-f5w6fw6q 2298 17 - - JJ cord-006870-f5w6fw6q 2298 18 pathway pathway JJ cord-006870-f5w6fw6q 2298 19 ) ) -RRB- cord-006870-f5w6fw6q 2298 20 . . . cord-006870-f5w6fw6q 2299 1 There there EX cord-006870-f5w6fw6q 2299 2 was be VBD cord-006870-f5w6fw6q 2299 3 no no DT cord-006870-f5w6fw6q 2299 4 statistically statistically RB cord-006870-f5w6fw6q 2299 5 significant significant JJ cord-006870-f5w6fw6q 2299 6 difference difference NN cord-006870-f5w6fw6q 2299 7 in in IN cord-006870-f5w6fw6q 2299 8 the the DT cord-006870-f5w6fw6q 2299 9 median median JJ cord-006870-f5w6fw6q 2299 10 frequency frequency NN cord-006870-f5w6fw6q 2299 11 of of IN cord-006870-f5w6fw6q 2299 12 RASS RASS NNP cord-006870-f5w6fw6q 2299 13 ( ( -LRB- cord-006870-f5w6fw6q 2299 14 4.8 4.8 CD cord-006870-f5w6fw6q 2299 15 vs. vs. IN cord-006870-f5w6fw6q 2299 16 4.1 4.1 CD cord-006870-f5w6fw6q 2299 17 ) ) -RRB- cord-006870-f5w6fw6q 2299 18 and and CC cord-006870-f5w6fw6q 2299 19 CPOT CPOT NNP cord-006870-f5w6fw6q 2299 20 ( ( -LRB- cord-006870-f5w6fw6q 2299 21 6.7 6.7 CD cord-006870-f5w6fw6q 2299 22 vs. vs. IN cord-006870-f5w6fw6q 2299 23 6.4 6.4 CD cord-006870-f5w6fw6q 2299 24 ) ) -RRB- cord-006870-f5w6fw6q 2299 25 assessments assessment NNS cord-006870-f5w6fw6q 2299 26 per per IN cord-006870-f5w6fw6q 2299 27 day day NN cord-006870-f5w6fw6q 2299 28 of of IN cord-006870-f5w6fw6q 2299 29 MV MV NNP cord-006870-f5w6fw6q 2299 30 or or CC cord-006870-f5w6fw6q 2299 31 in in IN cord-006870-f5w6fw6q 2299 32 median median JJ cord-006870-f5w6fw6q 2299 33 RASS RASS NNP cord-006870-f5w6fw6q 2299 34 ( ( -LRB- cord-006870-f5w6fw6q 2299 35 -3 -3 NNP cord-006870-f5w6fw6q 2299 36 vs. vs. IN cord-006870-f5w6fw6q 2299 37 -3 -3 NNP cord-006870-f5w6fw6q 2299 38 ) ) -RRB- cord-006870-f5w6fw6q 2299 39 and and CC cord-006870-f5w6fw6q 2299 40 CPOT CPOT NNP cord-006870-f5w6fw6q 2299 41 ( ( -LRB- cord-006870-f5w6fw6q 2299 42 0 0 NFP cord-006870-f5w6fw6q 2299 43 vs. vs. NN cord-006870-f5w6fw6q 2299 44 0 0 CD cord-006870-f5w6fw6q 2299 45 ) ) -RRB- cord-006870-f5w6fw6q 2299 46 scores score NNS cord-006870-f5w6fw6q 2299 47 . . . cord-006870-f5w6fw6q 2300 1 Mean mean JJ cord-006870-f5w6fw6q 2300 2 acetaminophen acetaminophen NN cord-006870-f5w6fw6q 2300 3 usage usage NN cord-006870-f5w6fw6q 2300 4 increased increase VBD cord-006870-f5w6fw6q 2300 5 from from IN cord-006870-f5w6fw6q 2300 6 85.1 85.1 CD cord-006870-f5w6fw6q 2300 7 % % NN cord-006870-f5w6fw6q 2300 8 to to TO cord-006870-f5w6fw6q 2300 9 100 100 CD cord-006870-f5w6fw6q 2300 10 % % NN cord-006870-f5w6fw6q 2300 11 ( ( -LRB- cord-006870-f5w6fw6q 2300 12 p p NN cord-006870-f5w6fw6q 2300 13 < < XX cord-006870-f5w6fw6q 2300 14 0.001 0.001 CD cord-006870-f5w6fw6q 2300 15 ) ) -RRB- cord-006870-f5w6fw6q 2300 16 post post JJ cord-006870-f5w6fw6q 2300 17 - - JJ cord-006870-f5w6fw6q 2300 18 pathway pathway JJ cord-006870-f5w6fw6q 2300 19 implementation implementation NN cord-006870-f5w6fw6q 2300 20 . . . cord-006870-f5w6fw6q 2301 1 There there EX cord-006870-f5w6fw6q 2301 2 was be VBD cord-006870-f5w6fw6q 2301 3 no no DT cord-006870-f5w6fw6q 2301 4 statistically statistically RB cord-006870-f5w6fw6q 2301 5 significant significant JJ cord-006870-f5w6fw6q 2301 6 difference difference NN cord-006870-f5w6fw6q 2301 7 in in IN cord-006870-f5w6fw6q 2301 8 mean mean JJ cord-006870-f5w6fw6q 2301 9 opioid opioid NN cord-006870-f5w6fw6q 2301 10 or or CC cord-006870-f5w6fw6q 2301 11 propofol propofol NN cord-006870-f5w6fw6q 2301 12 usage usage NN cord-006870-f5w6fw6q 2301 13 , , , cord-006870-f5w6fw6q 2301 14 however however RB cord-006870-f5w6fw6q 2301 15 a a DT cord-006870-f5w6fw6q 2301 16 trend trend NN cord-006870-f5w6fw6q 2301 17 toward toward IN cord-006870-f5w6fw6q 2301 18 increased increase VBN cord-006870-f5w6fw6q 2301 19 morphine morphine NN cord-006870-f5w6fw6q 2301 20 and and CC cord-006870-f5w6fw6q 2301 21 decreased decrease VBD cord-006870-f5w6fw6q 2301 22 propofol propofol NN cord-006870-f5w6fw6q 2301 23 usage usage NN cord-006870-f5w6fw6q 2301 24 was be VBD cord-006870-f5w6fw6q 2301 25 observed observe VBN cord-006870-f5w6fw6q 2301 26 post post JJ cord-006870-f5w6fw6q 2301 27 - - JJ cord-006870-f5w6fw6q 2301 28 pathway pathway JJ cord-006870-f5w6fw6q 2301 29 . . . cord-006870-f5w6fw6q 2302 1 Analgesia analgesia NN cord-006870-f5w6fw6q 2302 2 - - HYPH cord-006870-f5w6fw6q 2302 3 first first JJ cord-006870-f5w6fw6q 2302 4 sedation sedation NN cord-006870-f5w6fw6q 2302 5 pathway pathway NN cord-006870-f5w6fw6q 2302 6 implementation implementation NN cord-006870-f5w6fw6q 2302 7 trended trend VBD cord-006870-f5w6fw6q 2302 8 towards towards IN cord-006870-f5w6fw6q 2302 9 increased increase VBN cord-006870-f5w6fw6q 2302 10 opioid opioid JJ cord-006870-f5w6fw6q 2302 11 analgesic analgesic NN cord-006870-f5w6fw6q 2302 12 and and CC cord-006870-f5w6fw6q 2302 13 decreased decrease VBD cord-006870-f5w6fw6q 2302 14 sedative sedative JJ cord-006870-f5w6fw6q 2302 15 use use NN cord-006870-f5w6fw6q 2302 16 , , , cord-006870-f5w6fw6q 2302 17 however however RB cord-006870-f5w6fw6q 2302 18 only only RB cord-006870-f5w6fw6q 2302 19 increased increase VBD cord-006870-f5w6fw6q 2302 20 acetaminophen acetaminophen NN cord-006870-f5w6fw6q 2302 21 usage usage NN cord-006870-f5w6fw6q 2302 22 was be VBD cord-006870-f5w6fw6q 2302 23 significant significant JJ cord-006870-f5w6fw6q 2302 24 . . . cord-006870-f5w6fw6q 2303 1 This this DT cord-006870-f5w6fw6q 2303 2 highlights highlight VBZ cord-006870-f5w6fw6q 2303 3 challenges challenge NNS cord-006870-f5w6fw6q 2303 4 in in IN cord-006870-f5w6fw6q 2303 5 changing change VBG cord-006870-f5w6fw6q 2303 6 unit unit NN cord-006870-f5w6fw6q 2303 7 - - HYPH cord-006870-f5w6fw6q 2303 8 based base VBN cord-006870-f5w6fw6q 2303 9 practices practice NNS cord-006870-f5w6fw6q 2303 10 and and CC cord-006870-f5w6fw6q 2303 11 future future JJ cord-006870-f5w6fw6q 2303 12 directions direction NNS cord-006870-f5w6fw6q 2303 13 include include VBP cord-006870-f5w6fw6q 2303 14 focus focus NN cord-006870-f5w6fw6q 2303 15 on on IN cord-006870-f5w6fw6q 2303 16 the the DT cord-006870-f5w6fw6q 2303 17 frequency frequency NN cord-006870-f5w6fw6q 2303 18 and and CC cord-006870-f5w6fw6q 2303 19 reliability reliability NN cord-006870-f5w6fw6q 2303 20 of of IN cord-006870-f5w6fw6q 2303 21 pain pain NN cord-006870-f5w6fw6q 2303 22 , , , cord-006870-f5w6fw6q 2303 23 agitation agitation NN cord-006870-f5w6fw6q 2303 24 and and CC cord-006870-f5w6fw6q 2303 25 delirium delirium NN cord-006870-f5w6fw6q 2303 26 assessment assessment NN cord-006870-f5w6fw6q 2303 27 . . . cord-006870-f5w6fw6q 2304 1 Interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 2304 2 coordination coordination NN cord-006870-f5w6fw6q 2304 3 and and CC cord-006870-f5w6fw6q 2304 4 communication communication NN cord-006870-f5w6fw6q 2304 5 remains remain VBZ cord-006870-f5w6fw6q 2304 6 necessary necessary JJ cord-006870-f5w6fw6q 2304 7 for for IN cord-006870-f5w6fw6q 2304 8 effective effective JJ cord-006870-f5w6fw6q 2304 9 unit unit NN cord-006870-f5w6fw6q 2304 10 - - HYPH cord-006870-f5w6fw6q 2304 11 based base VBN cord-006870-f5w6fw6q 2304 12 practice practice NN cord-006870-f5w6fw6q 2304 13 changes change NNS cord-006870-f5w6fw6q 2304 14 . . . cord-006870-f5w6fw6q 2305 1 Andexanet Andexanet NNP cord-006870-f5w6fw6q 2305 2 alfa alfa NNP cord-006870-f5w6fw6q 2305 3 ( ( -LRB- cord-006870-f5w6fw6q 2305 4 andexanet andexanet NNP cord-006870-f5w6fw6q 2305 5 ) ) -RRB- cord-006870-f5w6fw6q 2305 6 , , , cord-006870-f5w6fw6q 2305 7 a a DT cord-006870-f5w6fw6q 2305 8 modified modify VBN cord-006870-f5w6fw6q 2305 9 , , , cord-006870-f5w6fw6q 2305 10 recombinant recombinant JJ cord-006870-f5w6fw6q 2305 11 human human JJ cord-006870-f5w6fw6q 2305 12 factor factor NN cord-006870-f5w6fw6q 2305 13 Xa Xa NNP cord-006870-f5w6fw6q 2305 14 ( ( -LRB- cord-006870-f5w6fw6q 2305 15 FXa FXa NNS cord-006870-f5w6fw6q 2305 16 ) ) -RRB- cord-006870-f5w6fw6q 2305 17 molecule molecule NN cord-006870-f5w6fw6q 2305 18 , , , cord-006870-f5w6fw6q 2305 19 binds bind VBZ cord-006870-f5w6fw6q 2305 20 and and CC cord-006870-f5w6fw6q 2305 21 sequesters sequester VBZ cord-006870-f5w6fw6q 2305 22 FXa FXa NNS cord-006870-f5w6fw6q 2305 23 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2305 24 . . . cord-006870-f5w6fw6q 2306 1 In in IN cord-006870-f5w6fw6q 2306 2 a a DT cord-006870-f5w6fw6q 2306 3 phase phase NN cord-006870-f5w6fw6q 2306 4 2 2 CD cord-006870-f5w6fw6q 2306 5 study study NN cord-006870-f5w6fw6q 2306 6 of of IN cord-006870-f5w6fw6q 2306 7 apixaban apixaban NNP cord-006870-f5w6fw6q 2306 8 , , , cord-006870-f5w6fw6q 2306 9 rivaroxaban rivaroxaban NNP cord-006870-f5w6fw6q 2306 10 , , , cord-006870-f5w6fw6q 2306 11 edoxaban edoxaban NNP cord-006870-f5w6fw6q 2306 12 , , , cord-006870-f5w6fw6q 2306 13 and and CC cord-006870-f5w6fw6q 2306 14 enoxaparin enoxaparin VBZ cord-006870-f5w6fw6q 2306 15 in in IN cord-006870-f5w6fw6q 2306 16 healthy healthy JJ cord-006870-f5w6fw6q 2306 17 volunteers volunteer NNS cord-006870-f5w6fw6q 2306 18 , , , cord-006870-f5w6fw6q 2306 19 andexanet andexanet VBP cord-006870-f5w6fw6q 2306 20 rapidly rapidly RB cord-006870-f5w6fw6q 2306 21 reversed reverse VBN cord-006870-f5w6fw6q 2306 22 pharmacodynamic pharmacodynamic JJ cord-006870-f5w6fw6q 2306 23 markers marker NNS cord-006870-f5w6fw6q 2306 24 of of IN cord-006870-f5w6fw6q 2306 25 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2306 26 . . . cord-006870-f5w6fw6q 2307 1 Here here RB cord-006870-f5w6fw6q 2307 2 , , , cord-006870-f5w6fw6q 2307 3 the the DT cord-006870-f5w6fw6q 2307 4 ability ability NN cord-006870-f5w6fw6q 2307 5 of of IN cord-006870-f5w6fw6q 2307 6 andexanet andexanet NN cord-006870-f5w6fw6q 2307 7 to to TO cord-006870-f5w6fw6q 2307 8 reverse reverse VB cord-006870-f5w6fw6q 2307 9 the the DT cord-006870-f5w6fw6q 2307 10 anticoagulant anticoagulant JJ cord-006870-f5w6fw6q 2307 11 activity activity NN cord-006870-f5w6fw6q 2307 12 of of IN cord-006870-f5w6fw6q 2307 13 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2307 14 was be VBD cord-006870-f5w6fw6q 2307 15 investigated investigate VBN cord-006870-f5w6fw6q 2307 16 . . . cord-006870-f5w6fw6q 2308 1 In in IN cord-006870-f5w6fw6q 2308 2 a a DT cord-006870-f5w6fw6q 2308 3 randomized randomized JJ cord-006870-f5w6fw6q 2308 4 , , , cord-006870-f5w6fw6q 2308 5 double double JJ cord-006870-f5w6fw6q 2308 6 - - HYPH cord-006870-f5w6fw6q 2308 7 blind blind JJ cord-006870-f5w6fw6q 2308 8 , , , cord-006870-f5w6fw6q 2308 9 phase phase NN cord-006870-f5w6fw6q 2308 10 2 2 CD cord-006870-f5w6fw6q 2308 11 study study NN cord-006870-f5w6fw6q 2308 12 in in IN cord-006870-f5w6fw6q 2308 13 healthy healthy JJ cord-006870-f5w6fw6q 2308 14 subjects subject NNS cord-006870-f5w6fw6q 2308 15 , , , cord-006870-f5w6fw6q 2308 16 andexanet andexanet NNP cord-006870-f5w6fw6q 2308 17 ( ( -LRB- cord-006870-f5w6fw6q 2308 18 n=12 n=12 NNP cord-006870-f5w6fw6q 2308 19 ) ) -RRB- cord-006870-f5w6fw6q 2308 20 or or CC cord-006870-f5w6fw6q 2308 21 placebo placebo NN cord-006870-f5w6fw6q 2308 22 ( ( -LRB- cord-006870-f5w6fw6q 2308 23 n=6 n=6 NN cord-006870-f5w6fw6q 2308 24 ) ) -RRB- cord-006870-f5w6fw6q 2308 25 was be VBD cord-006870-f5w6fw6q 2308 26 administered administer VBN cord-006870-f5w6fw6q 2308 27 intravenously intravenously RB cord-006870-f5w6fw6q 2308 28 following follow VBG cord-006870-f5w6fw6q 2308 29 80 80 CD cord-006870-f5w6fw6q 2308 30 mg mg NN cord-006870-f5w6fw6q 2308 31 PO po NN cord-006870-f5w6fw6q 2308 32 QD QD NNP cord-006870-f5w6fw6q 2308 33 betrixaban betrixaban VBN cord-006870-f5w6fw6q 2308 34 to to IN cord-006870-f5w6fw6q 2308 35 steady steady JJ cord-006870-f5w6fw6q 2308 36 state state NN cord-006870-f5w6fw6q 2308 37 ( ( -LRB- cord-006870-f5w6fw6q 2308 38 7 7 CD cord-006870-f5w6fw6q 2308 39 days day NNS cord-006870-f5w6fw6q 2308 40 ) ) -RRB- cord-006870-f5w6fw6q 2308 41 . . . cord-006870-f5w6fw6q 2309 1 In in IN cord-006870-f5w6fw6q 2309 2 Cohort cohort NN cord-006870-f5w6fw6q 2309 3 1 1 CD cord-006870-f5w6fw6q 2309 4 ( ( -LRB- cord-006870-f5w6fw6q 2309 5 andexanet andexanet NNP cord-006870-f5w6fw6q 2309 6 bolus bolus NN cord-006870-f5w6fw6q 2309 7 only only RB cord-006870-f5w6fw6q 2309 8 ) ) -RRB- cord-006870-f5w6fw6q 2309 9 , , , cord-006870-f5w6fw6q 2309 10 subjects subject NNS cord-006870-f5w6fw6q 2309 11 ( ( -LRB- cord-006870-f5w6fw6q 2309 12 n=6 n=6 NNP cord-006870-f5w6fw6q 2309 13 ) ) -RRB- cord-006870-f5w6fw6q 2309 14 received receive VBD cord-006870-f5w6fw6q 2309 15 a a DT cord-006870-f5w6fw6q 2309 16 800-mg 800-mg CD cord-006870-f5w6fw6q 2309 17 andexanet andexanet NN cord-006870-f5w6fw6q 2309 18 bolus bolus NN cord-006870-f5w6fw6q 2309 19 3 3 CD cord-006870-f5w6fw6q 2309 20 hours hour NNS cord-006870-f5w6fw6q 2309 21 after after IN cord-006870-f5w6fw6q 2309 22 the the DT cord-006870-f5w6fw6q 2309 23 last last JJ cord-006870-f5w6fw6q 2309 24 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2309 25 dose dose NN cord-006870-f5w6fw6q 2309 26 ( ( -LRB- cord-006870-f5w6fw6q 2309 27 Day Day NNP cord-006870-f5w6fw6q 2309 28 7 7 CD cord-006870-f5w6fw6q 2309 29 ) ) -RRB- cord-006870-f5w6fw6q 2309 30 or or CC cord-006870-f5w6fw6q 2309 31 placebo placebo NN cord-006870-f5w6fw6q 2309 32 ( ( -LRB- cord-006870-f5w6fw6q 2309 33 n=3 n=3 NN cord-006870-f5w6fw6q 2309 34 ) ) -RRB- cord-006870-f5w6fw6q 2309 35 . . . cord-006870-f5w6fw6q 2310 1 In in IN cord-006870-f5w6fw6q 2310 2 Cohort cohort NN cord-006870-f5w6fw6q 2310 3 2 2 CD cord-006870-f5w6fw6q 2310 4 ( ( -LRB- cord-006870-f5w6fw6q 2310 5 andexanet andexanet NNP cord-006870-f5w6fw6q 2310 6 bolus bolus NN cord-006870-f5w6fw6q 2310 7 plus plus CC cord-006870-f5w6fw6q 2310 8 2-hour 2-hour CD cord-006870-f5w6fw6q 2310 9 infusion infusion NN cord-006870-f5w6fw6q 2310 10 ) ) -RRB- cord-006870-f5w6fw6q 2310 11 , , , cord-006870-f5w6fw6q 2310 12 subjects subject NNS cord-006870-f5w6fw6q 2310 13 ( ( -LRB- cord-006870-f5w6fw6q 2310 14 n=6 n=6 NNP cord-006870-f5w6fw6q 2310 15 ) ) -RRB- cord-006870-f5w6fw6q 2310 16 received receive VBD cord-006870-f5w6fw6q 2310 17 a a DT cord-006870-f5w6fw6q 2310 18 800 800 CD cord-006870-f5w6fw6q 2310 19 mg mg NN cord-006870-f5w6fw6q 2310 20 andexanet andexanet NN cord-006870-f5w6fw6q 2310 21 bolus bolus NN cord-006870-f5w6fw6q 2310 22 4 4 CD cord-006870-f5w6fw6q 2310 23 hours hour NNS cord-006870-f5w6fw6q 2310 24 after after IN cord-006870-f5w6fw6q 2310 25 the the DT cord-006870-f5w6fw6q 2310 26 last last JJ cord-006870-f5w6fw6q 2310 27 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2310 28 dose dose NN cord-006870-f5w6fw6q 2310 29 , , , cord-006870-f5w6fw6q 2310 30 followed follow VBN cord-006870-f5w6fw6q 2310 31 by by IN cord-006870-f5w6fw6q 2310 32 a a DT cord-006870-f5w6fw6q 2310 33 2-hour 2-hour CD cord-006870-f5w6fw6q 2310 34 infusion infusion NN cord-006870-f5w6fw6q 2310 35 of of IN cord-006870-f5w6fw6q 2310 36 andexanet andexanet NNP cord-006870-f5w6fw6q 2310 37 ( ( -LRB- cord-006870-f5w6fw6q 2310 38 8mg 8mg NNP cord-006870-f5w6fw6q 2310 39 / / SYM cord-006870-f5w6fw6q 2310 40 min min NNP cord-006870-f5w6fw6q 2310 41 ) ) -RRB- cord-006870-f5w6fw6q 2310 42 or or CC cord-006870-f5w6fw6q 2310 43 placebo placebo NN cord-006870-f5w6fw6q 2310 44 ( ( -LRB- cord-006870-f5w6fw6q 2310 45 n=3 n=3 NN cord-006870-f5w6fw6q 2310 46 ) ) -RRB- cord-006870-f5w6fw6q 2310 47 . . . cord-006870-f5w6fw6q 2311 1 Endpoints endpoint NNS cord-006870-f5w6fw6q 2311 2 included include VBD cord-006870-f5w6fw6q 2311 3 safety safety NN cord-006870-f5w6fw6q 2311 4 and and CC cord-006870-f5w6fw6q 2311 5 pharmacodynamic pharmacodynamic JJ cord-006870-f5w6fw6q 2311 6 markers marker NNS cord-006870-f5w6fw6q 2311 7 of of IN cord-006870-f5w6fw6q 2311 8 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2311 9 reversal reversal NN cord-006870-f5w6fw6q 2311 10 . . . cord-006870-f5w6fw6q 2312 1 Following follow VBG cord-006870-f5w6fw6q 2312 2 treatment treatment NN cord-006870-f5w6fw6q 2312 3 with with IN cord-006870-f5w6fw6q 2312 4 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2312 5 in in IN cord-006870-f5w6fw6q 2312 6 Cohort Cohort NNP cord-006870-f5w6fw6q 2312 7 1 1 CD cord-006870-f5w6fw6q 2312 8 , , , cord-006870-f5w6fw6q 2312 9 andexanet andexanet NN cord-006870-f5w6fw6q 2312 10 rapidly rapidly RB cord-006870-f5w6fw6q 2312 11 decreased decrease VBD cord-006870-f5w6fw6q 2312 12 anti anti JJ cord-006870-f5w6fw6q 2312 13 - - JJ cord-006870-f5w6fw6q 2312 14 FXa fxa JJ cord-006870-f5w6fw6q 2312 15 activity activity NN cord-006870-f5w6fw6q 2312 16 from from IN cord-006870-f5w6fw6q 2312 17 29.9±11.6 29.9±11.6 CD cord-006870-f5w6fw6q 2312 18 to to IN cord-006870-f5w6fw6q 2312 19 6.5±4.5ng 6.5±4.5ng CD cord-006870-f5w6fw6q 2312 20 / / SYM cord-006870-f5w6fw6q 2312 21 mL ml NN cord-006870-f5w6fw6q 2312 22 , , , cord-006870-f5w6fw6q 2312 23 while while IN cord-006870-f5w6fw6q 2312 24 the the DT cord-006870-f5w6fw6q 2312 25 anti anti JJ cord-006870-f5w6fw6q 2312 26 - - JJ cord-006870-f5w6fw6q 2312 27 FXa fxa JJ cord-006870-f5w6fw6q 2312 28 levels level NNS cord-006870-f5w6fw6q 2312 29 following follow VBG cord-006870-f5w6fw6q 2312 30 placebo placebo NN cord-006870-f5w6fw6q 2312 31 were be VBD cord-006870-f5w6fw6q 2312 32 largely largely RB cord-006870-f5w6fw6q 2312 33 unchanged unchanged JJ cord-006870-f5w6fw6q 2312 34 ( ( -LRB- cord-006870-f5w6fw6q 2312 35 45.2±44.8 45.2±44.8 CD cord-006870-f5w6fw6q 2312 36 to to IN cord-006870-f5w6fw6q 2312 37 43.6±37.7ng 43.6±37.7ng CD cord-006870-f5w6fw6q 2312 38 / / SYM cord-006870-f5w6fw6q 2312 39 mL ml NN cord-006870-f5w6fw6q 2312 40 ) ) -RRB- cord-006870-f5w6fw6q 2312 41 . . . cord-006870-f5w6fw6q 2313 1 Unbound unbound JJ cord-006870-f5w6fw6q 2313 2 betrixaban betrixaban NN cord-006870-f5w6fw6q 2313 3 plasma plasma NN cord-006870-f5w6fw6q 2313 4 concentration concentration NN cord-006870-f5w6fw6q 2313 5 decreased decrease VBD cord-006870-f5w6fw6q 2313 6 from from IN cord-006870-f5w6fw6q 2313 7 12.3±5.6 12.3±5.6 CD cord-006870-f5w6fw6q 2313 8 to to IN cord-006870-f5w6fw6q 2313 9 3.6±2.7ng 3.6±2.7ng CD cord-006870-f5w6fw6q 2313 10 / / SYM cord-006870-f5w6fw6q 2313 11 mL ml NN cord-006870-f5w6fw6q 2313 12 with with IN cord-006870-f5w6fw6q 2313 13 andexanet andexanet NN cord-006870-f5w6fw6q 2313 14 , , , cord-006870-f5w6fw6q 2313 15 but but CC cord-006870-f5w6fw6q 2313 16 remained remain VBD cord-006870-f5w6fw6q 2313 17 constant constant JJ cord-006870-f5w6fw6q 2313 18 following follow VBG cord-006870-f5w6fw6q 2313 19 placebo placebo NN cord-006870-f5w6fw6q 2313 20 administration administration NN cord-006870-f5w6fw6q 2313 21 ( ( -LRB- cord-006870-f5w6fw6q 2313 22 18.3±17.9 18.3±17.9 CD cord-006870-f5w6fw6q 2313 23 to to IN cord-006870-f5w6fw6q 2313 24 19.3±18.1ng 19.3±18.1ng CD cord-006870-f5w6fw6q 2313 25 / / SYM cord-006870-f5w6fw6q 2313 26 mL ml NN cord-006870-f5w6fw6q 2313 27 ) ) -RRB- cord-006870-f5w6fw6q 2313 28 . . . cord-006870-f5w6fw6q 2314 1 Similar similar JJ cord-006870-f5w6fw6q 2314 2 results result NNS cord-006870-f5w6fw6q 2314 3 were be VBD cord-006870-f5w6fw6q 2314 4 observed observe VBN cord-006870-f5w6fw6q 2314 5 in in IN cord-006870-f5w6fw6q 2314 6 Cohort Cohort NNP cord-006870-f5w6fw6q 2314 7 2 2 CD cord-006870-f5w6fw6q 2314 8 following follow VBG cord-006870-f5w6fw6q 2314 9 andexanet andexanet NNP cord-006870-f5w6fw6q 2314 10 bolus bolus NN cord-006870-f5w6fw6q 2314 11 ( ( -LRB- cord-006870-f5w6fw6q 2314 12 2 2 CD cord-006870-f5w6fw6q 2314 13 minutes minute NNS cord-006870-f5w6fw6q 2314 14 after after IN cord-006870-f5w6fw6q 2314 15 bolus bolus NN cord-006870-f5w6fw6q 2314 16 ) ) -RRB- cord-006870-f5w6fw6q 2314 17 , , , cord-006870-f5w6fw6q 2314 18 and and CC cord-006870-f5w6fw6q 2314 19 the the DT cord-006870-f5w6fw6q 2314 20 effects effect NNS cord-006870-f5w6fw6q 2314 21 were be VBD cord-006870-f5w6fw6q 2314 22 maintained maintain VBN cord-006870-f5w6fw6q 2314 23 during during IN cord-006870-f5w6fw6q 2314 24 the the DT cord-006870-f5w6fw6q 2314 25 2-hour 2-hour CD cord-006870-f5w6fw6q 2314 26 infusion infusion NN cord-006870-f5w6fw6q 2314 27 of of IN cord-006870-f5w6fw6q 2314 28 andexanet andexanet NNP cord-006870-f5w6fw6q 2314 29 . . . cord-006870-f5w6fw6q 2315 1 For for IN cord-006870-f5w6fw6q 2315 2 Cohort cohort NN cord-006870-f5w6fw6q 2315 3 1 1 CD cord-006870-f5w6fw6q 2315 4 , , , cord-006870-f5w6fw6q 2315 5 thrombin thrombin JJ cord-006870-f5w6fw6q 2315 6 generation generation NN cord-006870-f5w6fw6q 2315 7 was be VBD cord-006870-f5w6fw6q 2315 8 restored restore VBN cord-006870-f5w6fw6q 2315 9 in in IN cord-006870-f5w6fw6q 2315 10 6/6 6/6 CD cord-006870-f5w6fw6q 2315 11 ( ( -LRB- cord-006870-f5w6fw6q 2315 12 100 100 CD cord-006870-f5w6fw6q 2315 13 % % NN cord-006870-f5w6fw6q 2315 14 ) ) -RRB- cord-006870-f5w6fw6q 2315 15 and and CC cord-006870-f5w6fw6q 2315 16 1/3 1/3 LS cord-006870-f5w6fw6q 2315 17 ( ( -LRB- cord-006870-f5w6fw6q 2315 18 33.3 33.3 CD cord-006870-f5w6fw6q 2315 19 % % NN cord-006870-f5w6fw6q 2315 20 ) ) -RRB- cord-006870-f5w6fw6q 2315 21 of of IN cord-006870-f5w6fw6q 2315 22 andexanet andexanet NN cord-006870-f5w6fw6q 2315 23 - - : cord-006870-f5w6fw6q 2315 24 administered administer VBN cord-006870-f5w6fw6q 2315 25 and and CC cord-006870-f5w6fw6q 2315 26 placebo placebo NN cord-006870-f5w6fw6q 2315 27 subjects subject NNS cord-006870-f5w6fw6q 2315 28 , , , cord-006870-f5w6fw6q 2315 29 respectively respectively RB cord-006870-f5w6fw6q 2315 30 . . . cord-006870-f5w6fw6q 2316 1 For for IN cord-006870-f5w6fw6q 2316 2 Cohort cohort NN cord-006870-f5w6fw6q 2316 3 2 2 CD cord-006870-f5w6fw6q 2316 4 , , , cord-006870-f5w6fw6q 2316 5 thrombin thrombin JJ cord-006870-f5w6fw6q 2316 6 generation generation NN cord-006870-f5w6fw6q 2316 7 was be VBD cord-006870-f5w6fw6q 2316 8 restored restore VBN cord-006870-f5w6fw6q 2316 9 in in IN cord-006870-f5w6fw6q 2316 10 5/6 5/6 CD cord-006870-f5w6fw6q 2316 11 ( ( -LRB- cord-006870-f5w6fw6q 2316 12 83.3 83.3 CD cord-006870-f5w6fw6q 2316 13 % % NN cord-006870-f5w6fw6q 2316 14 ) ) -RRB- cord-006870-f5w6fw6q 2316 15 of of IN cord-006870-f5w6fw6q 2316 16 andexanet andexanet NN cord-006870-f5w6fw6q 2316 17 subjects subject NNS cord-006870-f5w6fw6q 2316 18 versus versus IN cord-006870-f5w6fw6q 2316 19 1/3 1/3 CD cord-006870-f5w6fw6q 2316 20 ( ( -LRB- cord-006870-f5w6fw6q 2316 21 33.3 33.3 CD cord-006870-f5w6fw6q 2316 22 % % NN cord-006870-f5w6fw6q 2316 23 ) ) -RRB- cord-006870-f5w6fw6q 2316 24 of of IN cord-006870-f5w6fw6q 2316 25 placebo placebo NN cord-006870-f5w6fw6q 2316 26 subjects subject NNS cord-006870-f5w6fw6q 2316 27 . . . cord-006870-f5w6fw6q 2317 1 Andexanet Andexanet NNP cord-006870-f5w6fw6q 2317 2 was be VBD cord-006870-f5w6fw6q 2317 3 well well RB cord-006870-f5w6fw6q 2317 4 tolerated tolerate VBN cord-006870-f5w6fw6q 2317 5 ; ; : cord-006870-f5w6fw6q 2317 6 there there EX cord-006870-f5w6fw6q 2317 7 were be VBD cord-006870-f5w6fw6q 2317 8 no no DT cord-006870-f5w6fw6q 2317 9 thrombotic thrombotic JJ cord-006870-f5w6fw6q 2317 10 events event NNS cord-006870-f5w6fw6q 2317 11 or or CC cord-006870-f5w6fw6q 2317 12 serious serious JJ cord-006870-f5w6fw6q 2317 13 / / SYM cord-006870-f5w6fw6q 2317 14 severe severe JJ cord-006870-f5w6fw6q 2317 15 adverse adverse JJ cord-006870-f5w6fw6q 2317 16 events event NNS cord-006870-f5w6fw6q 2317 17 . . . cord-006870-f5w6fw6q 2318 1 Andexanet Andexanet NNP cord-006870-f5w6fw6q 2318 2 was be VBD cord-006870-f5w6fw6q 2318 3 well well RB cord-006870-f5w6fw6q 2318 4 tolerated tolerate VBN cord-006870-f5w6fw6q 2318 5 and and CC cord-006870-f5w6fw6q 2318 6 rapidly rapidly RB cord-006870-f5w6fw6q 2318 7 reversed reverse VBN cord-006870-f5w6fw6q 2318 8 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2318 9 effects effect NNS cord-006870-f5w6fw6q 2318 10 of of IN cord-006870-f5w6fw6q 2318 11 betrixaban betrixaban NN cord-006870-f5w6fw6q 2318 12 in in IN cord-006870-f5w6fw6q 2318 13 healthy healthy JJ cord-006870-f5w6fw6q 2318 14 subjects subject NNS cord-006870-f5w6fw6q 2318 15 . . . cord-006870-f5w6fw6q 2319 1 These these DT cord-006870-f5w6fw6q 2319 2 and and CC cord-006870-f5w6fw6q 2319 3 other other JJ cord-006870-f5w6fw6q 2319 4 studies study NNS cord-006870-f5w6fw6q 2319 5 indicate indicate VBP cord-006870-f5w6fw6q 2319 6 that that IN cord-006870-f5w6fw6q 2319 7 andexanet andexanet NNP cord-006870-f5w6fw6q 2319 8 could could MD cord-006870-f5w6fw6q 2319 9 be be VB cord-006870-f5w6fw6q 2319 10 a a DT cord-006870-f5w6fw6q 2319 11 universal universal JJ cord-006870-f5w6fw6q 2319 12 antidote antidote NN cord-006870-f5w6fw6q 2319 13 for for IN cord-006870-f5w6fw6q 2319 14 FXa FXa NNS cord-006870-f5w6fw6q 2319 15 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2319 16 . . . cord-006870-f5w6fw6q 2320 1 Andexanet Andexanet NNP cord-006870-f5w6fw6q 2320 2 alfa alfa NNP cord-006870-f5w6fw6q 2320 3 ( ( -LRB- cord-006870-f5w6fw6q 2320 4 AnXa AnXa NNP cord-006870-f5w6fw6q 2320 5 ) ) -RRB- cord-006870-f5w6fw6q 2320 6 , , , cord-006870-f5w6fw6q 2320 7 a a DT cord-006870-f5w6fw6q 2320 8 recombinant recombinant JJ cord-006870-f5w6fw6q 2320 9 human human JJ cord-006870-f5w6fw6q 2320 10 FXa FXa NNS cord-006870-f5w6fw6q 2320 11 molecule molecule NN cord-006870-f5w6fw6q 2320 12 , , , cord-006870-f5w6fw6q 2320 13 reverses reverse VBZ cord-006870-f5w6fw6q 2320 14 the the DT cord-006870-f5w6fw6q 2320 15 anticoagulant anticoagulant JJ cord-006870-f5w6fw6q 2320 16 activity activity NN cord-006870-f5w6fw6q 2320 17 of of IN cord-006870-f5w6fw6q 2320 18 FXa FXa NNS cord-006870-f5w6fw6q 2320 19 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2320 20 . . . cord-006870-f5w6fw6q 2321 1 In in IN cord-006870-f5w6fw6q 2321 2 studies study NNS cord-006870-f5w6fw6q 2321 3 of of IN cord-006870-f5w6fw6q 2321 4 healthy healthy JJ cord-006870-f5w6fw6q 2321 5 volunteers volunteer NNS cord-006870-f5w6fw6q 2321 6 , , , cord-006870-f5w6fw6q 2321 7 AnXa AnXa NNP cord-006870-f5w6fw6q 2321 8 showed show VBD cord-006870-f5w6fw6q 2321 9 dose dose NN cord-006870-f5w6fw6q 2321 10 - - HYPH cord-006870-f5w6fw6q 2321 11 dependent dependent JJ cord-006870-f5w6fw6q 2321 12 reversal reversal NN cord-006870-f5w6fw6q 2321 13 of of IN cord-006870-f5w6fw6q 2321 14 direct direct JJ cord-006870-f5w6fw6q 2321 15 and and CC cord-006870-f5w6fw6q 2321 16 indirect indirect JJ cord-006870-f5w6fw6q 2321 17 FXa FXa NNS cord-006870-f5w6fw6q 2321 18 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2321 19 in in IN cord-006870-f5w6fw6q 2321 20 tissue tissue NN cord-006870-f5w6fw6q 2321 21 factor factor NN cord-006870-f5w6fw6q 2321 22 ( ( -LRB- cord-006870-f5w6fw6q 2321 23 TF)-initiated tf)-initiated CD cord-006870-f5w6fw6q 2321 24 thrombin thrombin JJ cord-006870-f5w6fw6q 2321 25 generation generation NN cord-006870-f5w6fw6q 2321 26 ( ( -LRB- cord-006870-f5w6fw6q 2321 27 TG TG NNP cord-006870-f5w6fw6q 2321 28 ) ) -RRB- cord-006870-f5w6fw6q 2321 29 . . . cord-006870-f5w6fw6q 2322 1 We -PRON- PRP cord-006870-f5w6fw6q 2322 2 compared compare VBD cord-006870-f5w6fw6q 2322 3 rivaroxabaninduced rivaroxabaninduced JJ cord-006870-f5w6fw6q 2322 4 inhibition inhibition NN cord-006870-f5w6fw6q 2322 5 of of IN cord-006870-f5w6fw6q 2322 6 TG TG NNP cord-006870-f5w6fw6q 2322 7 initiated initiate VBD cord-006870-f5w6fw6q 2322 8 via via IN cord-006870-f5w6fw6q 2322 9 the the DT cord-006870-f5w6fw6q 2322 10 extrinsic extrinsic JJ cord-006870-f5w6fw6q 2322 11 pathway pathway NN cord-006870-f5w6fw6q 2322 12 ( ( -LRB- cord-006870-f5w6fw6q 2322 13 TF TF NNP cord-006870-f5w6fw6q 2322 14 ) ) -RRB- cord-006870-f5w6fw6q 2322 15 versus versus IN cord-006870-f5w6fw6q 2322 16 intrinsic intrinsic JJ cord-006870-f5w6fw6q 2322 17 pathway pathway NN cord-006870-f5w6fw6q 2322 18 ( ( -LRB- cord-006870-f5w6fw6q 2322 19 non non NNP cord-006870-f5w6fw6q 2322 20 - - JJ cord-006870-f5w6fw6q 2322 21 TF TF NNP cord-006870-f5w6fw6q 2322 22 ) ) -RRB- cord-006870-f5w6fw6q 2322 23 . . . cord-006870-f5w6fw6q 2323 1 TF TF NNP cord-006870-f5w6fw6q 2323 2 - - HYPH cord-006870-f5w6fw6q 2323 3 initiated initiate VBN cord-006870-f5w6fw6q 2323 4 TG TG NNP cord-006870-f5w6fw6q 2323 5 was be VBD cord-006870-f5w6fw6q 2323 6 measured measure VBN cord-006870-f5w6fw6q 2323 7 using use VBG cord-006870-f5w6fw6q 2323 8 a a DT cord-006870-f5w6fw6q 2323 9 calibrated calibrate VBN cord-006870-f5w6fw6q 2323 10 automated automate VBN cord-006870-f5w6fw6q 2323 11 thrombogram thrombogram NNP cord-006870-f5w6fw6q 2323 12 ( ( -LRB- cord-006870-f5w6fw6q 2323 13 CAT CAT NNP cord-006870-f5w6fw6q 2323 14 ) ) -RRB- cord-006870-f5w6fw6q 2323 15 and and CC cord-006870-f5w6fw6q 2323 16 PPP PPP NNP cord-006870-f5w6fw6q 2323 17 - - HYPH cord-006870-f5w6fw6q 2323 18 reagent reagent NN cord-006870-f5w6fw6q 2323 19 . . . cord-006870-f5w6fw6q 2324 1 Non Non NNP cord-006870-f5w6fw6q 2324 2 - - NNP cord-006870-f5w6fw6q 2324 3 TF tf NN cord-006870-f5w6fw6q 2324 4 - - HYPH cord-006870-f5w6fw6q 2324 5 initiated initiate VBN cord-006870-f5w6fw6q 2324 6 TG TG NNP cord-006870-f5w6fw6q 2324 7 was be VBD cord-006870-f5w6fw6q 2324 8 measured measure VBN cord-006870-f5w6fw6q 2324 9 using use VBG cord-006870-f5w6fw6q 2324 10 CAT CAT NNP cord-006870-f5w6fw6q 2324 11 and and CC cord-006870-f5w6fw6q 2324 12 Actin Actin NNP cord-006870-f5w6fw6q 2324 13 FS FS NNP cord-006870-f5w6fw6q 2324 14 . . . cord-006870-f5w6fw6q 2325 1 Anti anti JJ cord-006870-f5w6fw6q 2325 2 - - JJ cord-006870-f5w6fw6q 2325 3 FXa fxa JJ cord-006870-f5w6fw6q 2325 4 activity activity NN cord-006870-f5w6fw6q 2325 5 was be VBD cord-006870-f5w6fw6q 2325 6 measured measure VBN cord-006870-f5w6fw6q 2325 7 using use VBG cord-006870-f5w6fw6q 2325 8 an an DT cord-006870-f5w6fw6q 2325 9 anti anti JJ cord-006870-f5w6fw6q 2325 10 - - JJ cord-006870-f5w6fw6q 2325 11 FXa fxa JJ cord-006870-f5w6fw6q 2325 12 chromogenic chromogenic JJ cord-006870-f5w6fw6q 2325 13 assay assay NN cord-006870-f5w6fw6q 2325 14 . . . cord-006870-f5w6fw6q 2326 1 Pooled pool VBN cord-006870-f5w6fw6q 2326 2 plasma plasma NN cord-006870-f5w6fw6q 2326 3 was be VBD cord-006870-f5w6fw6q 2326 4 spiked spike VBN cord-006870-f5w6fw6q 2326 5 with with IN cord-006870-f5w6fw6q 2326 6 rivaroxaban rivaroxaban NNS cord-006870-f5w6fw6q 2326 7 or or CC cord-006870-f5w6fw6q 2326 8 rivaroxaban+AnXa rivaroxaban+anxa NN cord-006870-f5w6fw6q 2326 9 ; ; : cord-006870-f5w6fw6q 2326 10 TG TG NNP cord-006870-f5w6fw6q 2326 11 , , , cord-006870-f5w6fw6q 2326 12 anti anti JJ cord-006870-f5w6fw6q 2326 13 - - JJ cord-006870-f5w6fw6q 2326 14 FXa fxa JJ cord-006870-f5w6fw6q 2326 15 activity activity NN cord-006870-f5w6fw6q 2326 16 , , , cord-006870-f5w6fw6q 2326 17 and and CC cord-006870-f5w6fw6q 2326 18 clot clot NN cord-006870-f5w6fw6q 2326 19 formation formation NN cord-006870-f5w6fw6q 2326 20 were be VBD cord-006870-f5w6fw6q 2326 21 measured measure VBN cord-006870-f5w6fw6q 2326 22 . . . cord-006870-f5w6fw6q 2327 1 For for IN cord-006870-f5w6fw6q 2327 2 low low JJ cord-006870-f5w6fw6q 2327 3 TF tf NN cord-006870-f5w6fw6q 2327 4 - - HYPH cord-006870-f5w6fw6q 2327 5 initiated initiate VBN cord-006870-f5w6fw6q 2327 6 clot clot NN cord-006870-f5w6fw6q 2327 7 formation formation NN cord-006870-f5w6fw6q 2327 8 , , , cord-006870-f5w6fw6q 2327 9 thromboelastography thromboelastography NN cord-006870-f5w6fw6q 2327 10 profiles profile NNS cord-006870-f5w6fw6q 2327 11 were be VBD cord-006870-f5w6fw6q 2327 12 measured measure VBN cord-006870-f5w6fw6q 2327 13 . . . cord-006870-f5w6fw6q 2328 1 AnXa AnXa NNP cord-006870-f5w6fw6q 2328 2 alone alone RB cord-006870-f5w6fw6q 2328 3 had have VBD cord-006870-f5w6fw6q 2328 4 minimal minimal JJ cord-006870-f5w6fw6q 2328 5 effect effect NN cord-006870-f5w6fw6q 2328 6 on on IN cord-006870-f5w6fw6q 2328 7 endogenous endogenous JJ cord-006870-f5w6fw6q 2328 8 thrombin thrombin NN cord-006870-f5w6fw6q 2328 9 potential potential NN cord-006870-f5w6fw6q 2328 10 ( ( -LRB- cord-006870-f5w6fw6q 2328 11 ETP ETP NNP cord-006870-f5w6fw6q 2328 12 ) ) -RRB- cord-006870-f5w6fw6q 2328 13 . . . cord-006870-f5w6fw6q 2329 1 AnXa AnXa NNP cord-006870-f5w6fw6q 2329 2 fully fully RB cord-006870-f5w6fw6q 2329 3 reversed reverse VBD cord-006870-f5w6fw6q 2329 4 rivaroxaban rivaroxaban NN cord-006870-f5w6fw6q 2329 5 - - HYPH cord-006870-f5w6fw6q 2329 6 induced induce VBN cord-006870-f5w6fw6q 2329 7 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2329 8 in in IN cord-006870-f5w6fw6q 2329 9 the the DT cord-006870-f5w6fw6q 2329 10 Actin Actin NNP cord-006870-f5w6fw6q 2329 11 FS FS NNP cord-006870-f5w6fw6q 2329 12 assay assay NN cord-006870-f5w6fw6q 2329 13 , , , cord-006870-f5w6fw6q 2329 14 independent independent JJ cord-006870-f5w6fw6q 2329 15 of of IN cord-006870-f5w6fw6q 2329 16 AnXa AnXa NNP cord-006870-f5w6fw6q 2329 17 - - HYPH cord-006870-f5w6fw6q 2329 18 TFPI TFPI NNP cord-006870-f5w6fw6q 2329 19 interaction interaction NN cord-006870-f5w6fw6q 2329 20 . . . cord-006870-f5w6fw6q 2330 1 Modulation modulation NN cord-006870-f5w6fw6q 2330 2 of of IN cord-006870-f5w6fw6q 2330 3 TF TF NNP cord-006870-f5w6fw6q 2330 4 activity activity NN cord-006870-f5w6fw6q 2330 5 was be VBD cord-006870-f5w6fw6q 2330 6 assessed assess VBN cord-006870-f5w6fw6q 2330 7 by by IN cord-006870-f5w6fw6q 2330 8 correlating correlate VBG cord-006870-f5w6fw6q 2330 9 ETP ETP NNP cord-006870-f5w6fw6q 2330 10 versus versus IN cord-006870-f5w6fw6q 2330 11 anti anti JJ cord-006870-f5w6fw6q 2330 12 - - JJ cord-006870-f5w6fw6q 2330 13 FXa fxa JJ cord-006870-f5w6fw6q 2330 14 activity activity NN cord-006870-f5w6fw6q 2330 15 with with IN cord-006870-f5w6fw6q 2330 16 rivaroxaban rivaroxaban NNP cord-006870-f5w6fw6q 2330 17 or or CC cord-006870-f5w6fw6q 2330 18 rivaroxaban+AnXa rivaroxaban+anxa NN cord-006870-f5w6fw6q 2330 19 . . . cord-006870-f5w6fw6q 2331 1 Rivaroxaban Rivaroxaban NNP cord-006870-f5w6fw6q 2331 2 dose dose NN cord-006870-f5w6fw6q 2331 3 - - HYPH cord-006870-f5w6fw6q 2331 4 dependently dependently RB cord-006870-f5w6fw6q 2331 5 inhibited inhibit VBN cord-006870-f5w6fw6q 2331 6 TF TF NNP cord-006870-f5w6fw6q 2331 7 - - HYPH cord-006870-f5w6fw6q 2331 8 initiated initiate VBN cord-006870-f5w6fw6q 2331 9 TG TG NNP cord-006870-f5w6fw6q 2331 10 as as IN cord-006870-f5w6fw6q 2331 11 anti anti JJ cord-006870-f5w6fw6q 2331 12 - - JJ cord-006870-f5w6fw6q 2331 13 FXa fxa JJ cord-006870-f5w6fw6q 2331 14 activity activity NN cord-006870-f5w6fw6q 2331 15 increased increase VBD cord-006870-f5w6fw6q 2331 16 . . . cord-006870-f5w6fw6q 2332 1 At at IN cord-006870-f5w6fw6q 2332 2 similar similar JJ cord-006870-f5w6fw6q 2332 3 anti anti JJ cord-006870-f5w6fw6q 2332 4 - - JJ cord-006870-f5w6fw6q 2332 5 FXa fxa JJ cord-006870-f5w6fw6q 2332 6 levels level NNS cord-006870-f5w6fw6q 2332 7 , , , cord-006870-f5w6fw6q 2332 8 rivaroxaban+AnXa rivaroxaban+AnXa NNS cord-006870-f5w6fw6q 2332 9 had have VBD cord-006870-f5w6fw6q 2332 10 higher high JJR cord-006870-f5w6fw6q 2332 11 ETP ETP NNP cord-006870-f5w6fw6q 2332 12 than than IN cord-006870-f5w6fw6q 2332 13 rivaroxaban rivaroxaban NNP cord-006870-f5w6fw6q 2332 14 alone alone RB cord-006870-f5w6fw6q 2332 15 , , , cord-006870-f5w6fw6q 2332 16 but but CC cord-006870-f5w6fw6q 2332 17 not not RB cord-006870-f5w6fw6q 2332 18 in in IN cord-006870-f5w6fw6q 2332 19 the the DT cord-006870-f5w6fw6q 2332 20 Actin Actin NNP cord-006870-f5w6fw6q 2332 21 FS FS NNP cord-006870-f5w6fw6q 2332 22 assay assay NN cord-006870-f5w6fw6q 2332 23 . . . cord-006870-f5w6fw6q 2333 1 Clot clot NN cord-006870-f5w6fw6q 2333 2 formation formation NN cord-006870-f5w6fw6q 2333 3 was be VBD cord-006870-f5w6fw6q 2333 4 studied study VBN cord-006870-f5w6fw6q 2333 5 in in IN cord-006870-f5w6fw6q 2333 6 plasma plasma NN cord-006870-f5w6fw6q 2333 7 using use VBG cord-006870-f5w6fw6q 2333 8 thromboelastography thromboelastography NNP cord-006870-f5w6fw6q 2333 9 without without IN cord-006870-f5w6fw6q 2333 10 rivaroxaban rivaroxaban NNP cord-006870-f5w6fw6q 2333 11 . . . cord-006870-f5w6fw6q 2334 1 AnXa AnXa NNP cord-006870-f5w6fw6q 2334 2 did do VBD cord-006870-f5w6fw6q 2334 3 not not RB cord-006870-f5w6fw6q 2334 4 affect affect VB cord-006870-f5w6fw6q 2334 5 thromboelastography thromboelastography NN cord-006870-f5w6fw6q 2334 6 parameters parameter NNS cord-006870-f5w6fw6q 2334 7 , , , cord-006870-f5w6fw6q 2334 8 with with IN cord-006870-f5w6fw6q 2334 9 / / SYM cord-006870-f5w6fw6q 2334 10 without without IN cord-006870-f5w6fw6q 2334 11 recombinant recombinant JJ cord-006870-f5w6fw6q 2334 12 tissue tissue NN cord-006870-f5w6fw6q 2334 13 plasminogen plasminogen NN cord-006870-f5w6fw6q 2334 14 activator activator NN cord-006870-f5w6fw6q 2334 15 ( ( -LRB- cord-006870-f5w6fw6q 2334 16 rtPA rtPA NNP cord-006870-f5w6fw6q 2334 17 ) ) -RRB- cord-006870-f5w6fw6q 2334 18 . . . cord-006870-f5w6fw6q 2335 1 When when WRB cord-006870-f5w6fw6q 2335 2 low low JJ cord-006870-f5w6fw6q 2335 3 TF TF NNP cord-006870-f5w6fw6q 2335 4 initiated initiate VBD cord-006870-f5w6fw6q 2335 5 clot clot NN cord-006870-f5w6fw6q 2335 6 formation formation NN cord-006870-f5w6fw6q 2335 7 without without IN cord-006870-f5w6fw6q 2335 8 rtPA rtPA NNP cord-006870-f5w6fw6q 2335 9 , , , cord-006870-f5w6fw6q 2335 10 AnXa AnXa NNP cord-006870-f5w6fw6q 2335 11 reduced reduce VBD cord-006870-f5w6fw6q 2335 12 the the DT cord-006870-f5w6fw6q 2335 13 thromboelastography thromboelastography NN cord-006870-f5w6fw6q 2335 14 - - HYPH cord-006870-f5w6fw6q 2335 15 R r NN cord-006870-f5w6fw6q 2335 16 parameter parameter NN cord-006870-f5w6fw6q 2335 17 , , , cord-006870-f5w6fw6q 2335 18 but but CC cord-006870-f5w6fw6q 2335 19 not not RB cord-006870-f5w6fw6q 2335 20 maximum maximum JJ cord-006870-f5w6fw6q 2335 21 amplitude amplitude NN cord-006870-f5w6fw6q 2335 22 . . . cord-006870-f5w6fw6q 2336 1 The the DT cord-006870-f5w6fw6q 2336 2 fibrin fibrin NN cord-006870-f5w6fw6q 2336 3 clot clot NN cord-006870-f5w6fw6q 2336 4 was be VBD cord-006870-f5w6fw6q 2336 5 lysed lyse VBN cord-006870-f5w6fw6q 2336 6 at at IN cord-006870-f5w6fw6q 2336 7 low low JJ cord-006870-f5w6fw6q 2336 8 rtPA rtPA NNP cord-006870-f5w6fw6q 2336 9 , , , cord-006870-f5w6fw6q 2336 10 resulting result VBG cord-006870-f5w6fw6q 2336 11 in in IN cord-006870-f5w6fw6q 2336 12 well well RB cord-006870-f5w6fw6q 2336 13 - - HYPH cord-006870-f5w6fw6q 2336 14 segregated segregate VBN cord-006870-f5w6fw6q 2336 15 coagulation coagulation NN cord-006870-f5w6fw6q 2336 16 and and CC cord-006870-f5w6fw6q 2336 17 fibrinolysis fibrinolysis NN cord-006870-f5w6fw6q 2336 18 . . . cord-006870-f5w6fw6q 2337 1 With with IN cord-006870-f5w6fw6q 2337 2 the the DT cord-006870-f5w6fw6q 2337 3 optimal optimal JJ cord-006870-f5w6fw6q 2337 4 rtPA rtpa NN cord-006870-f5w6fw6q 2337 5 , , , cord-006870-f5w6fw6q 2337 6 fibrin fibrin NN cord-006870-f5w6fw6q 2337 7 clots clot NNS cord-006870-f5w6fw6q 2337 8 formed form VBN cord-006870-f5w6fw6q 2337 9 at at IN cord-006870-f5w6fw6q 2337 10 each each DT cord-006870-f5w6fw6q 2337 11 TF TF NNP cord-006870-f5w6fw6q 2337 12 concentration concentration NN cord-006870-f5w6fw6q 2337 13 were be VBD cord-006870-f5w6fw6q 2337 14 compensated compensate VBN cord-006870-f5w6fw6q 2337 15 by by IN cord-006870-f5w6fw6q 2337 16 the the DT cord-006870-f5w6fw6q 2337 17 fibrinolytic fibrinolytic JJ cord-006870-f5w6fw6q 2337 18 activity activity NN cord-006870-f5w6fw6q 2337 19 of of IN cord-006870-f5w6fw6q 2337 20 rtPA rtPA NNP cord-006870-f5w6fw6q 2337 21 . . . cord-006870-f5w6fw6q 2338 1 Without without IN cord-006870-f5w6fw6q 2338 2 a a DT cord-006870-f5w6fw6q 2338 3 FXa FXa NNS cord-006870-f5w6fw6q 2338 4 inhibitor inhibitor NN cord-006870-f5w6fw6q 2338 5 , , , cord-006870-f5w6fw6q 2338 6 AnXa AnXa NNP cord-006870-f5w6fw6q 2338 7 had have VBD cord-006870-f5w6fw6q 2338 8 minimal minimal JJ cord-006870-f5w6fw6q 2338 9 effect effect NN cord-006870-f5w6fw6q 2338 10 on on IN cord-006870-f5w6fw6q 2338 11 TF TF NNP cord-006870-f5w6fw6q 2338 12 or or CC cord-006870-f5w6fw6q 2338 13 Actin Actin NNP cord-006870-f5w6fw6q 2338 14 FS FS NNP cord-006870-f5w6fw6q 2338 15 - - HYPH cord-006870-f5w6fw6q 2338 16 initiated initiate VBN cord-006870-f5w6fw6q 2338 17 TG TG NNP cord-006870-f5w6fw6q 2338 18 with with IN cord-006870-f5w6fw6q 2338 19 no no DT cord-006870-f5w6fw6q 2338 20 direct direct JJ cord-006870-f5w6fw6q 2338 21 effect effect NN cord-006870-f5w6fw6q 2338 22 on on IN cord-006870-f5w6fw6q 2338 23 rtPA rtPA NNP cord-006870-f5w6fw6q 2338 24 function function NN cord-006870-f5w6fw6q 2338 25 . . . cord-006870-f5w6fw6q 2339 1 AnXa AnXa NNP cord-006870-f5w6fw6q 2339 2 dose dose NN cord-006870-f5w6fw6q 2339 3 - - : cord-006870-f5w6fw6q 2339 4 dependently dependently RB cord-006870-f5w6fw6q 2339 5 and and CC cord-006870-f5w6fw6q 2339 6 completely completely RB cord-006870-f5w6fw6q 2339 7 reversed reverse VBN cord-006870-f5w6fw6q 2339 8 rivaroxaban rivaroxaban NN cord-006870-f5w6fw6q 2339 9 - - HYPH cord-006870-f5w6fw6q 2339 10 induced induce VBN cord-006870-f5w6fw6q 2339 11 inhibition inhibition NN cord-006870-f5w6fw6q 2339 12 of of IN cord-006870-f5w6fw6q 2339 13 TG TG NNP cord-006870-f5w6fw6q 2339 14 initiated initiate VBN cord-006870-f5w6fw6q 2339 15 by by IN cord-006870-f5w6fw6q 2339 16 intrinsic intrinsic JJ cord-006870-f5w6fw6q 2339 17 or or CC cord-006870-f5w6fw6q 2339 18 extrinsic extrinsic JJ cord-006870-f5w6fw6q 2339 19 pathways pathway NNS cord-006870-f5w6fw6q 2339 20 , , , cord-006870-f5w6fw6q 2339 21 but but CC cord-006870-f5w6fw6q 2339 22 had have VBD cord-006870-f5w6fw6q 2339 23 different different JJ cord-006870-f5w6fw6q 2339 24 effects effect NNS cord-006870-f5w6fw6q 2339 25 on on IN cord-006870-f5w6fw6q 2339 26 ETP ETP NNP cord-006870-f5w6fw6q 2339 27 due due IN cord-006870-f5w6fw6q 2339 28 to to IN cord-006870-f5w6fw6q 2339 29 the the DT cord-006870-f5w6fw6q 2339 30 AnXa AnXa NNP cord-006870-f5w6fw6q 2339 31 - - HYPH cord-006870-f5w6fw6q 2339 32 TFPI TFPI NNP cord-006870-f5w6fw6q 2339 33 interaction interaction NN cord-006870-f5w6fw6q 2339 34 . . . cord-006870-f5w6fw6q 2340 1 There there EX cord-006870-f5w6fw6q 2340 2 is be VBZ cord-006870-f5w6fw6q 2340 3 a a DT cord-006870-f5w6fw6q 2340 4 growing grow VBG cord-006870-f5w6fw6q 2340 5 body body NN cord-006870-f5w6fw6q 2340 6 of of IN cord-006870-f5w6fw6q 2340 7 evidence evidence NN cord-006870-f5w6fw6q 2340 8 relating relate VBG cord-006870-f5w6fw6q 2340 9 poor poor JJ cord-006870-f5w6fw6q 2340 10 outcomes outcome NNS cord-006870-f5w6fw6q 2340 11 to to IN cord-006870-f5w6fw6q 2340 12 off off IN cord-006870-f5w6fw6q 2340 13 - - HYPH cord-006870-f5w6fw6q 2340 14 hour hour NN cord-006870-f5w6fw6q 2340 15 management management NN cord-006870-f5w6fw6q 2340 16 . . . cord-006870-f5w6fw6q 2341 1 Studies study NNS cord-006870-f5w6fw6q 2341 2 investigating investigate VBG cord-006870-f5w6fw6q 2341 3 the the DT cord-006870-f5w6fw6q 2341 4 effect effect NN cord-006870-f5w6fw6q 2341 5 of of IN cord-006870-f5w6fw6q 2341 6 overnight overnight JJ cord-006870-f5w6fw6q 2341 7 extubation extubation NN cord-006870-f5w6fw6q 2341 8 ( ( -LRB- cord-006870-f5w6fw6q 2341 9 OE OE NNP cord-006870-f5w6fw6q 2341 10 ) ) -RRB- cord-006870-f5w6fw6q 2341 11 have have VBP cord-006870-f5w6fw6q 2341 12 produced produce VBN cord-006870-f5w6fw6q 2341 13 mixed mixed JJ cord-006870-f5w6fw6q 2341 14 results result NNS cord-006870-f5w6fw6q 2341 15 , , , cord-006870-f5w6fw6q 2341 16 and and CC cord-006870-f5w6fw6q 2341 17 limited limited JJ cord-006870-f5w6fw6q 2341 18 data datum NNS cord-006870-f5w6fw6q 2341 19 is be VBZ cord-006870-f5w6fw6q 2341 20 available available JJ cord-006870-f5w6fw6q 2341 21 for for IN cord-006870-f5w6fw6q 2341 22 brain brain NN cord-006870-f5w6fw6q 2341 23 - - HYPH cord-006870-f5w6fw6q 2341 24 injured injure VBN cord-006870-f5w6fw6q 2341 25 patients patient NNS cord-006870-f5w6fw6q 2341 26 . . . cord-006870-f5w6fw6q 2342 1 There there EX cord-006870-f5w6fw6q 2342 2 may may MD cord-006870-f5w6fw6q 2342 3 also also RB cord-006870-f5w6fw6q 2342 4 be be VB cord-006870-f5w6fw6q 2342 5 tendency tendency JJ cord-006870-f5w6fw6q 2342 6 to to TO cord-006870-f5w6fw6q 2342 7 limit limit VB cord-006870-f5w6fw6q 2342 8 OE OE NNP cord-006870-f5w6fw6q 2342 9 due due IN cord-006870-f5w6fw6q 2342 10 to to IN cord-006870-f5w6fw6q 2342 11 decreased decrease VBN cord-006870-f5w6fw6q 2342 12 staffing staffing NN cord-006870-f5w6fw6q 2342 13 levels level NNS cord-006870-f5w6fw6q 2342 14 at at IN cord-006870-f5w6fw6q 2342 15 night night NN cord-006870-f5w6fw6q 2342 16 . . . cord-006870-f5w6fw6q 2343 1 We -PRON- PRP cord-006870-f5w6fw6q 2343 2 sought seek VBD cord-006870-f5w6fw6q 2343 3 to to TO cord-006870-f5w6fw6q 2343 4 determine determine VB cord-006870-f5w6fw6q 2343 5 the the DT cord-006870-f5w6fw6q 2343 6 safety safety NN cord-006870-f5w6fw6q 2343 7 of of IN cord-006870-f5w6fw6q 2343 8 OE OE NNP cord-006870-f5w6fw6q 2343 9 and and CC cord-006870-f5w6fw6q 2343 10 risk risk NN cord-006870-f5w6fw6q 2343 11 factor factor NN cord-006870-f5w6fw6q 2343 12 profiles profile NNS cord-006870-f5w6fw6q 2343 13 associated associate VBN cord-006870-f5w6fw6q 2343 14 with with IN cord-006870-f5w6fw6q 2343 15 extubation extubation NN cord-006870-f5w6fw6q 2343 16 failure failure NN cord-006870-f5w6fw6q 2343 17 ( ( -LRB- cord-006870-f5w6fw6q 2343 18 EF EF NNP cord-006870-f5w6fw6q 2343 19 ) ) -RRB- cord-006870-f5w6fw6q 2343 20 in in IN cord-006870-f5w6fw6q 2343 21 this this DT cord-006870-f5w6fw6q 2343 22 cohort cohort NN cord-006870-f5w6fw6q 2343 23 . . . cord-006870-f5w6fw6q 2344 1 We -PRON- PRP cord-006870-f5w6fw6q 2344 2 conducted conduct VBD cord-006870-f5w6fw6q 2344 3 a a DT cord-006870-f5w6fw6q 2344 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2344 5 review review NN cord-006870-f5w6fw6q 2344 6 of of IN cord-006870-f5w6fw6q 2344 7 mechanically mechanically RB cord-006870-f5w6fw6q 2344 8 ventilated ventilate VBN cord-006870-f5w6fw6q 2344 9 patients patient NNS cord-006870-f5w6fw6q 2344 10 admitted admit VBN cord-006870-f5w6fw6q 2344 11 to to IN cord-006870-f5w6fw6q 2344 12 a a DT cord-006870-f5w6fw6q 2344 13 single single JJ cord-006870-f5w6fw6q 2344 14 - - HYPH cord-006870-f5w6fw6q 2344 15 center center NN cord-006870-f5w6fw6q 2344 16 in in IN cord-006870-f5w6fw6q 2344 17 - - HYPH cord-006870-f5w6fw6q 2344 18 house house NN cord-006870-f5w6fw6q 2344 19 database database NN cord-006870-f5w6fw6q 2344 20 . . . cord-006870-f5w6fw6q 2345 1 Exclusion exclusion NN cord-006870-f5w6fw6q 2345 2 criteria criterion NNS cord-006870-f5w6fw6q 2345 3 included include VBD cord-006870-f5w6fw6q 2345 4 limitations limitation NNS cord-006870-f5w6fw6q 2345 5 in in IN cord-006870-f5w6fw6q 2345 6 care care NN cord-006870-f5w6fw6q 2345 7 , , , cord-006870-f5w6fw6q 2345 8 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2345 9 placement placement NN cord-006870-f5w6fw6q 2345 10 , , , cord-006870-f5w6fw6q 2345 11 selfextubation selfextubation NN cord-006870-f5w6fw6q 2345 12 , , , cord-006870-f5w6fw6q 2345 13 and and CC cord-006870-f5w6fw6q 2345 14 death death NN cord-006870-f5w6fw6q 2345 15 prior prior RB cord-006870-f5w6fw6q 2345 16 to to IN cord-006870-f5w6fw6q 2345 17 extubation extubation NN cord-006870-f5w6fw6q 2345 18 . . . cord-006870-f5w6fw6q 2346 1 The the DT cord-006870-f5w6fw6q 2346 2 primary primary JJ cord-006870-f5w6fw6q 2346 3 outcome outcome NN cord-006870-f5w6fw6q 2346 4 was be VBD cord-006870-f5w6fw6q 2346 5 EF EF NNP cord-006870-f5w6fw6q 2346 6 defined define VBN cord-006870-f5w6fw6q 2346 7 as as IN cord-006870-f5w6fw6q 2346 8 non non JJ cord-006870-f5w6fw6q 2346 9 - - JJ cord-006870-f5w6fw6q 2346 10 elective elective JJ cord-006870-f5w6fw6q 2346 11 endotracheal endotracheal NN cord-006870-f5w6fw6q 2346 12 intubation intubation NN cord-006870-f5w6fw6q 2346 13 within within IN cord-006870-f5w6fw6q 2346 14 72 72 CD cord-006870-f5w6fw6q 2346 15 hours hour NNS cord-006870-f5w6fw6q 2346 16 . . . cord-006870-f5w6fw6q 2347 1 EF EF NNP cord-006870-f5w6fw6q 2347 2 rates rate NNS cord-006870-f5w6fw6q 2347 3 were be VBD cord-006870-f5w6fw6q 2347 4 compared compare VBN cord-006870-f5w6fw6q 2347 5 between between IN cord-006870-f5w6fw6q 2347 6 daytime daytime NN cord-006870-f5w6fw6q 2347 7 ( ( -LRB- cord-006870-f5w6fw6q 2347 8 6AM 6AM NNP cord-006870-f5w6fw6q 2347 9 -5:59PM -5:59PM NNP cord-006870-f5w6fw6q 2347 10 ) ) -RRB- cord-006870-f5w6fw6q 2347 11 and and CC cord-006870-f5w6fw6q 2347 12 overnight overnight RB cord-006870-f5w6fw6q 2347 13 ( ( -LRB- cord-006870-f5w6fw6q 2347 14 6PM 6PM NNP cord-006870-f5w6fw6q 2347 15 -5:59AM -5:59am ADD cord-006870-f5w6fw6q 2347 16 ) ) -RRB- cord-006870-f5w6fw6q 2347 17 extubation extubation NN cord-006870-f5w6fw6q 2347 18 cohorts cohort NNS cord-006870-f5w6fw6q 2347 19 . . . cord-006870-f5w6fw6q 2348 1 In in IN cord-006870-f5w6fw6q 2348 2 - - HYPH cord-006870-f5w6fw6q 2348 3 hospital hospital NN cord-006870-f5w6fw6q 2348 4 mortality mortality NN cord-006870-f5w6fw6q 2348 5 served serve VBD cord-006870-f5w6fw6q 2348 6 as as IN cord-006870-f5w6fw6q 2348 7 a a DT cord-006870-f5w6fw6q 2348 8 secondary secondary JJ cord-006870-f5w6fw6q 2348 9 outcome outcome NN cord-006870-f5w6fw6q 2348 10 . . . cord-006870-f5w6fw6q 2349 1 Amongst amongst IN cord-006870-f5w6fw6q 2349 2 997 997 CD cord-006870-f5w6fw6q 2349 3 identified identify VBD cord-006870-f5w6fw6q 2349 4 patients patient NNS cord-006870-f5w6fw6q 2349 5 , , , cord-006870-f5w6fw6q 2349 6 783 783 CD cord-006870-f5w6fw6q 2349 7 ( ( -LRB- cord-006870-f5w6fw6q 2349 8 78.5 78.5 CD cord-006870-f5w6fw6q 2349 9 % % NN cord-006870-f5w6fw6q 2349 10 ) ) -RRB- cord-006870-f5w6fw6q 2349 11 underwent undergo VBD cord-006870-f5w6fw6q 2349 12 daytime daytime JJ cord-006870-f5w6fw6q 2349 13 extubation extubation NN cord-006870-f5w6fw6q 2349 14 ( ( -LRB- cord-006870-f5w6fw6q 2349 15 DE DE NNP cord-006870-f5w6fw6q 2349 16 ) ) -RRB- cord-006870-f5w6fw6q 2349 17 and and CC cord-006870-f5w6fw6q 2349 18 214 214 CD cord-006870-f5w6fw6q 2350 1 ( ( -LRB- cord-006870-f5w6fw6q 2350 2 21.5 21.5 CD cord-006870-f5w6fw6q 2350 3 % % NN cord-006870-f5w6fw6q 2350 4 ) ) -RRB- cord-006870-f5w6fw6q 2350 5 OE OE NNP cord-006870-f5w6fw6q 2350 6 . . . cord-006870-f5w6fw6q 2351 1 EF EF NNP cord-006870-f5w6fw6q 2351 2 was be VBD cord-006870-f5w6fw6q 2351 3 indifferent indifferent JJ cord-006870-f5w6fw6q 2351 4 between between IN cord-006870-f5w6fw6q 2351 5 DE DE NNP cord-006870-f5w6fw6q 2351 6 and and CC cord-006870-f5w6fw6q 2351 7 OE OE NNP cord-006870-f5w6fw6q 2351 8 ( ( -LRB- cord-006870-f5w6fw6q 2351 9 10.1 10.1 CD cord-006870-f5w6fw6q 2351 10 % % NN cord-006870-f5w6fw6q 2351 11 and and CC cord-006870-f5w6fw6q 2351 12 8.4 8.4 CD cord-006870-f5w6fw6q 2351 13 % % NN cord-006870-f5w6fw6q 2351 14 respectively respectively RB cord-006870-f5w6fw6q 2351 15 ; ; : cord-006870-f5w6fw6q 2351 16 p=0.46 p=0.46 NNP cord-006870-f5w6fw6q 2351 17 ) ) -RRB- cord-006870-f5w6fw6q 2351 18 . . . cord-006870-f5w6fw6q 2352 1 However however RB cord-006870-f5w6fw6q 2352 2 , , , cord-006870-f5w6fw6q 2352 3 multivariable multivariable JJ cord-006870-f5w6fw6q 2352 4 adjustment adjustment NN cord-006870-f5w6fw6q 2352 5 for for IN cord-006870-f5w6fw6q 2352 6 clinical clinical JJ cord-006870-f5w6fw6q 2352 7 severity severity NN cord-006870-f5w6fw6q 2352 8 indicators indicator NNS cord-006870-f5w6fw6q 2352 9 suggests suggest VBZ cord-006870-f5w6fw6q 2352 10 higher high JJR cord-006870-f5w6fw6q 2352 11 EF EF NNP cord-006870-f5w6fw6q 2352 12 for for IN cord-006870-f5w6fw6q 2352 13 OE OE NNP cord-006870-f5w6fw6q 2352 14 ( ( -LRB- cord-006870-f5w6fw6q 2352 15 OR or NN cord-006870-f5w6fw6q 2352 16 : : : cord-006870-f5w6fw6q 2352 17 1.16 1.16 CD cord-006870-f5w6fw6q 2352 18 , , , cord-006870-f5w6fw6q 2352 19 CI CI NNP cord-006870-f5w6fw6q 2352 20 : : : cord-006870-f5w6fw6q 2352 21 0.65 0.65 CD cord-006870-f5w6fw6q 2352 22 - - HYPH cord-006870-f5w6fw6q 2352 23 2.06 2.06 CD cord-006870-f5w6fw6q 2352 24 ; ; : cord-006870-f5w6fw6q 2352 25 p=0.61 p=0.61 NN cord-006870-f5w6fw6q 2352 26 ) ) -RRB- cord-006870-f5w6fw6q 2352 27 . . . cord-006870-f5w6fw6q 2353 1 Compared compare VBN cord-006870-f5w6fw6q 2353 2 to to IN cord-006870-f5w6fw6q 2353 3 DE DE NNP cord-006870-f5w6fw6q 2353 4 , , , cord-006870-f5w6fw6q 2353 5 OE OE NNP cord-006870-f5w6fw6q 2353 6 was be VBD cord-006870-f5w6fw6q 2353 7 more more RBR cord-006870-f5w6fw6q 2353 8 likely likely RB cord-006870-f5w6fw6q 2353 9 performed perform VBN cord-006870-f5w6fw6q 2353 10 in in IN cord-006870-f5w6fw6q 2353 11 elective elective JJ cord-006870-f5w6fw6q 2353 12 post post JJ cord-006870-f5w6fw6q 2353 13 - - JJ cord-006870-f5w6fw6q 2353 14 operative operative JJ cord-006870-f5w6fw6q 2353 15 patients patient NNS cord-006870-f5w6fw6q 2353 16 ( ( -LRB- cord-006870-f5w6fw6q 2353 17 29.9 29.9 CD cord-006870-f5w6fw6q 2353 18 % % NN cord-006870-f5w6fw6q 2353 19 vs vs IN cord-006870-f5w6fw6q 2353 20 21.1 21.1 CD cord-006870-f5w6fw6q 2353 21 % % NN cord-006870-f5w6fw6q 2353 22 ; ; , cord-006870-f5w6fw6q 2353 23 p=0.006 p=0.006 NNS cord-006870-f5w6fw6q 2353 24 ) ) -RRB- cord-006870-f5w6fw6q 2353 25 with with IN cord-006870-f5w6fw6q 2353 26 lower low JJR cord-006870-f5w6fw6q 2353 27 APACHE APACHE NNP cord-006870-f5w6fw6q 2353 28 - - HYPH cord-006870-f5w6fw6q 2353 29 II II NNP cord-006870-f5w6fw6q 2353 30 scores score NNS cord-006870-f5w6fw6q 2353 31 ( ( -LRB- cord-006870-f5w6fw6q 2353 32 median median JJ cord-006870-f5w6fw6q 2353 33 11 11 CD cord-006870-f5w6fw6q 2353 34 vs vs IN cord-006870-f5w6fw6q 2353 35 13 13 CD cord-006870-f5w6fw6q 2353 36 ; ; : cord-006870-f5w6fw6q 2353 37 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 2353 38 ) ) -RRB- cord-006870-f5w6fw6q 2353 39 , , , cord-006870-f5w6fw6q 2353 40 and and CC cord-006870-f5w6fw6q 2353 41 shorter short JJR cord-006870-f5w6fw6q 2353 42 durations duration NNS cord-006870-f5w6fw6q 2353 43 of of IN cord-006870-f5w6fw6q 2353 44 MV MV NNP cord-006870-f5w6fw6q 2353 45 ( ( -LRB- cord-006870-f5w6fw6q 2353 46 median median NN cord-006870-f5w6fw6q 2353 47 0.3 0.3 CD cord-006870-f5w6fw6q 2353 48 vs vs IN cord-006870-f5w6fw6q 2353 49 1.4 1.4 CD cord-006870-f5w6fw6q 2353 50 days day NNS cord-006870-f5w6fw6q 2353 51 ; ; : cord-006870-f5w6fw6q 2353 52 < < XX cord-006870-f5w6fw6q 2353 53 0.001 0.001 CD cord-006870-f5w6fw6q 2353 54 ) ) -RRB- cord-006870-f5w6fw6q 2353 55 . . . cord-006870-f5w6fw6q 2354 1 Higher high JJR cord-006870-f5w6fw6q 2354 2 APACHE APACHE NNP cord-006870-f5w6fw6q 2354 3 - - HYPH cord-006870-f5w6fw6q 2354 4 II II NNP cord-006870-f5w6fw6q 2354 5 score score NN cord-006870-f5w6fw6q 2354 6 , , , cord-006870-f5w6fw6q 2354 7 longer long JJR cord-006870-f5w6fw6q 2354 8 duration duration NN cord-006870-f5w6fw6q 2354 9 of of IN cord-006870-f5w6fw6q 2354 10 MV MV NNP cord-006870-f5w6fw6q 2354 11 , , , cord-006870-f5w6fw6q 2354 12 and and CC cord-006870-f5w6fw6q 2354 13 admission admission NN cord-006870-f5w6fw6q 2354 14 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2354 15 of of IN cord-006870-f5w6fw6q 2354 16 acute acute JJ cord-006870-f5w6fw6q 2354 17 vascular vascular JJ cord-006870-f5w6fw6q 2354 18 injury injury NN cord-006870-f5w6fw6q 2354 19 or or CC cord-006870-f5w6fw6q 2354 20 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 2354 21 disease disease NN cord-006870-f5w6fw6q 2354 22 were be VBD cord-006870-f5w6fw6q 2354 23 associated associate VBN cord-006870-f5w6fw6q 2354 24 with with IN cord-006870-f5w6fw6q 2354 25 EF EF NNP cord-006870-f5w6fw6q 2354 26 . . . cord-006870-f5w6fw6q 2355 1 There there EX cord-006870-f5w6fw6q 2355 2 was be VBD cord-006870-f5w6fw6q 2355 3 no no DT cord-006870-f5w6fw6q 2355 4 difference difference NN cord-006870-f5w6fw6q 2355 5 in in IN cord-006870-f5w6fw6q 2355 6 mortality mortality NN cord-006870-f5w6fw6q 2355 7 ( ( -LRB- cord-006870-f5w6fw6q 2355 8 p=0.91 p=0.91 NNP cord-006870-f5w6fw6q 2355 9 ) ) -RRB- cord-006870-f5w6fw6q 2355 10 . . . cord-006870-f5w6fw6q 2356 1 In in IN cord-006870-f5w6fw6q 2356 2 our -PRON- PRP$ cord-006870-f5w6fw6q 2356 3 cohort cohort NN cord-006870-f5w6fw6q 2356 4 , , , cord-006870-f5w6fw6q 2356 5 OE OE NNP cord-006870-f5w6fw6q 2356 6 was be VBD cord-006870-f5w6fw6q 2356 7 not not RB cord-006870-f5w6fw6q 2356 8 associated associate VBN cord-006870-f5w6fw6q 2356 9 with with IN cord-006870-f5w6fw6q 2356 10 increased increase VBN cord-006870-f5w6fw6q 2356 11 EF ef NN cord-006870-f5w6fw6q 2356 12 or or CC cord-006870-f5w6fw6q 2356 13 mortality mortality NN cord-006870-f5w6fw6q 2356 14 . . . cord-006870-f5w6fw6q 2357 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2357 2 results result NNS cord-006870-f5w6fw6q 2357 3 suggest suggest VBP cord-006870-f5w6fw6q 2357 4 that that IN cord-006870-f5w6fw6q 2357 5 OE OE NNP cord-006870-f5w6fw6q 2357 6 can can MD cord-006870-f5w6fw6q 2357 7 be be VB cord-006870-f5w6fw6q 2357 8 performed perform VBN cord-006870-f5w6fw6q 2357 9 safely safely RB cord-006870-f5w6fw6q 2357 10 if if IN cord-006870-f5w6fw6q 2357 11 standard standard JJ cord-006870-f5w6fw6q 2357 12 extubation extubation NN cord-006870-f5w6fw6q 2357 13 criteria criterion NNS cord-006870-f5w6fw6q 2357 14 are be VBP cord-006870-f5w6fw6q 2357 15 met meet VBN cord-006870-f5w6fw6q 2357 16 in in IN cord-006870-f5w6fw6q 2357 17 low low JJ cord-006870-f5w6fw6q 2357 18 - - HYPH cord-006870-f5w6fw6q 2357 19 risk risk NN cord-006870-f5w6fw6q 2357 20 patients patient NNS cord-006870-f5w6fw6q 2357 21 . . . cord-006870-f5w6fw6q 2358 1 These these DT cord-006870-f5w6fw6q 2358 2 data datum NNS cord-006870-f5w6fw6q 2358 3 provide provide VBP cord-006870-f5w6fw6q 2358 4 a a DT cord-006870-f5w6fw6q 2358 5 basis basis NN cord-006870-f5w6fw6q 2358 6 for for IN cord-006870-f5w6fw6q 2358 7 subsequent subsequent JJ cord-006870-f5w6fw6q 2358 8 more more RBR cord-006870-f5w6fw6q 2358 9 robust robust JJ cord-006870-f5w6fw6q 2358 10 studies study NNS cord-006870-f5w6fw6q 2358 11 . . . cord-006870-f5w6fw6q 2359 1 Case Case NNP cord-006870-f5w6fw6q 2359 2 series series NN cord-006870-f5w6fw6q 2359 3 have have VBP cord-006870-f5w6fw6q 2359 4 reported report VBN cord-006870-f5w6fw6q 2359 5 reversible reversible JJ cord-006870-f5w6fw6q 2359 6 left leave VBN cord-006870-f5w6fw6q 2359 7 ventricular ventricular JJ cord-006870-f5w6fw6q 2359 8 dysfunction dysfunction NN cord-006870-f5w6fw6q 2359 9 , , , cord-006870-f5w6fw6q 2359 10 also also RB cord-006870-f5w6fw6q 2359 11 known know VBN cord-006870-f5w6fw6q 2359 12 as as IN cord-006870-f5w6fw6q 2359 13 stress stress NN cord-006870-f5w6fw6q 2359 14 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2359 15 or or CC cord-006870-f5w6fw6q 2359 16 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2359 17 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2359 18 , , , cord-006870-f5w6fw6q 2359 19 in in IN cord-006870-f5w6fw6q 2359 20 the the DT cord-006870-f5w6fw6q 2359 21 setting setting NN cord-006870-f5w6fw6q 2359 22 of of IN cord-006870-f5w6fw6q 2359 23 acute acute JJ cord-006870-f5w6fw6q 2359 24 neurological neurological JJ cord-006870-f5w6fw6q 2359 25 diseases disease NNS cord-006870-f5w6fw6q 2359 26 such such JJ cord-006870-f5w6fw6q 2359 27 as as IN cord-006870-f5w6fw6q 2359 28 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2359 29 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2359 30 . . . cord-006870-f5w6fw6q 2360 1 The the DT cord-006870-f5w6fw6q 2360 2 nature nature NN cord-006870-f5w6fw6q 2360 3 of of IN cord-006870-f5w6fw6q 2360 4 the the DT cord-006870-f5w6fw6q 2360 5 association association NN cord-006870-f5w6fw6q 2360 6 between between IN cord-006870-f5w6fw6q 2360 7 various various JJ cord-006870-f5w6fw6q 2360 8 neurological neurological JJ cord-006870-f5w6fw6q 2360 9 diseases disease NNS cord-006870-f5w6fw6q 2360 10 and and CC cord-006870-f5w6fw6q 2360 11 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2360 12 remains remain VBZ cord-006870-f5w6fw6q 2360 13 incompletely incompletely RB cord-006870-f5w6fw6q 2360 14 understood understand VBN cord-006870-f5w6fw6q 2360 15 . . . cord-006870-f5w6fw6q 2361 1 We -PRON- PRP cord-006870-f5w6fw6q 2361 2 performed perform VBD cord-006870-f5w6fw6q 2361 3 a a DT cord-006870-f5w6fw6q 2361 4 cross cross JJ cord-006870-f5w6fw6q 2361 5 - - JJ cord-006870-f5w6fw6q 2361 6 sectional sectional JJ cord-006870-f5w6fw6q 2361 7 study study NN cord-006870-f5w6fw6q 2361 8 of of IN cord-006870-f5w6fw6q 2361 9 all all DT cord-006870-f5w6fw6q 2361 10 adults adult NNS cord-006870-f5w6fw6q 2361 11 in in IN cord-006870-f5w6fw6q 2361 12 the the DT cord-006870-f5w6fw6q 2361 13 National National NNP cord-006870-f5w6fw6q 2361 14 Inpatient Inpatient NNP cord-006870-f5w6fw6q 2361 15 Sample Sample NNP cord-006870-f5w6fw6q 2361 16 , , , cord-006870-f5w6fw6q 2361 17 a a DT cord-006870-f5w6fw6q 2361 18 nationally nationally RB cord-006870-f5w6fw6q 2361 19 representative representative JJ cord-006870-f5w6fw6q 2361 20 sample sample NN cord-006870-f5w6fw6q 2361 21 of of IN cord-006870-f5w6fw6q 2361 22 U.S. U.S. NNP cord-006870-f5w6fw6q 2361 23 hospitalizations hospitalization NNS cord-006870-f5w6fw6q 2361 24 , , , cord-006870-f5w6fw6q 2361 25 from from IN cord-006870-f5w6fw6q 2361 26 2006 2006 CD cord-006870-f5w6fw6q 2361 27 - - SYM cord-006870-f5w6fw6q 2361 28 2013 2013 CD cord-006870-f5w6fw6q 2361 29 . . . cord-006870-f5w6fw6q 2362 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2362 2 exposures exposure NNS cord-006870-f5w6fw6q 2362 3 of of IN cord-006870-f5w6fw6q 2362 4 interest interest NN cord-006870-f5w6fw6q 2362 5 were be VBD cord-006870-f5w6fw6q 2362 6 primary primary JJ cord-006870-f5w6fw6q 2362 7 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2362 8 of of IN cord-006870-f5w6fw6q 2362 9 acute acute JJ cord-006870-f5w6fw6q 2362 10 neurological neurological JJ cord-006870-f5w6fw6q 2362 11 disease disease NN cord-006870-f5w6fw6q 2362 12 , , , cord-006870-f5w6fw6q 2362 13 defined define VBN cord-006870-f5w6fw6q 2362 14 by by IN cord-006870-f5w6fw6q 2362 15 ICD-9-CM ICD-9-CM NNP cord-006870-f5w6fw6q 2362 16 diagnosis diagnosis NN cord-006870-f5w6fw6q 2362 17 codes code NNS cord-006870-f5w6fw6q 2362 18 . . . cord-006870-f5w6fw6q 2363 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2363 2 outcome outcome NN cord-006870-f5w6fw6q 2363 3 was be VBD cord-006870-f5w6fw6q 2363 4 a a DT cord-006870-f5w6fw6q 2363 5 diagnosis diagnosis NN cord-006870-f5w6fw6q 2363 6 of of IN cord-006870-f5w6fw6q 2363 7 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2363 8 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2363 9 . . . cord-006870-f5w6fw6q 2364 1 Binary binary JJ cord-006870-f5w6fw6q 2364 2 logistic logistic JJ cord-006870-f5w6fw6q 2364 3 regression regression NN cord-006870-f5w6fw6q 2364 4 models model NNS cord-006870-f5w6fw6q 2364 5 were be VBD cord-006870-f5w6fw6q 2364 6 used use VBN cord-006870-f5w6fw6q 2364 7 to to TO cord-006870-f5w6fw6q 2364 8 examine examine VB cord-006870-f5w6fw6q 2364 9 the the DT cord-006870-f5w6fw6q 2364 10 associations association NNS cord-006870-f5w6fw6q 2364 11 between between IN cord-006870-f5w6fw6q 2364 12 our -PRON- PRP$ cord-006870-f5w6fw6q 2364 13 prespecified prespecified JJ cord-006870-f5w6fw6q 2364 14 neurological neurological JJ cord-006870-f5w6fw6q 2364 15 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2364 16 and and CC cord-006870-f5w6fw6q 2364 17 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2364 18 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2364 19 after after IN cord-006870-f5w6fw6q 2364 20 adjustment adjustment NN cord-006870-f5w6fw6q 2364 21 for for IN cord-006870-f5w6fw6q 2364 22 demographics demographic NNS cord-006870-f5w6fw6q 2364 23 . . . cord-006870-f5w6fw6q 2365 1 We -PRON- PRP cord-006870-f5w6fw6q 2365 2 identified identify VBD cord-006870-f5w6fw6q 2365 3 18,321,298 18,321,298 CD cord-006870-f5w6fw6q 2365 4 adults adult NNS cord-006870-f5w6fw6q 2365 5 with with IN cord-006870-f5w6fw6q 2365 6 a a DT cord-006870-f5w6fw6q 2365 7 primary primary JJ cord-006870-f5w6fw6q 2365 8 acute acute JJ cord-006870-f5w6fw6q 2365 9 neurological neurological JJ cord-006870-f5w6fw6q 2365 10 diagnosis diagnosis NN cord-006870-f5w6fw6q 2365 11 and and CC cord-006870-f5w6fw6q 2365 12 231,416,640 231,416,640 CD cord-006870-f5w6fw6q 2365 13 patients patient NNS cord-006870-f5w6fw6q 2365 14 admitted admit VBN cord-006870-f5w6fw6q 2365 15 to to IN cord-006870-f5w6fw6q 2365 16 the the DT cord-006870-f5w6fw6q 2365 17 hospital hospital NN cord-006870-f5w6fw6q 2365 18 without without IN cord-006870-f5w6fw6q 2365 19 a a DT cord-006870-f5w6fw6q 2365 20 primary primary JJ cord-006870-f5w6fw6q 2365 21 acute acute JJ cord-006870-f5w6fw6q 2365 22 neurological neurological JJ cord-006870-f5w6fw6q 2365 23 diagnosis diagnosis NN cord-006870-f5w6fw6q 2365 24 . . . cord-006870-f5w6fw6q 2366 1 Among among IN cord-006870-f5w6fw6q 2366 2 neurological neurological JJ cord-006870-f5w6fw6q 2366 3 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2366 4 , , , cord-006870-f5w6fw6q 2366 5 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2366 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2366 7 ( ( -LRB- cord-006870-f5w6fw6q 2366 8 odds odd NNS cord-006870-f5w6fw6q 2366 9 ratio ratio NN cord-006870-f5w6fw6q 2366 10 [ [ -LRB- cord-006870-f5w6fw6q 2366 11 OR or CC cord-006870-f5w6fw6q 2366 12 ] ] -RRB- cord-006870-f5w6fw6q 2366 13 , , , cord-006870-f5w6fw6q 2366 14 9.20 9.20 CD cord-006870-f5w6fw6q 2366 15 ; ; : cord-006870-f5w6fw6q 2366 16 95%CI 95%ci CD cord-006870-f5w6fw6q 2366 17 , , , cord-006870-f5w6fw6q 2366 18 , , , cord-006870-f5w6fw6q 2366 19 status status NN cord-006870-f5w6fw6q 2366 20 epilepticus epilepticus NN cord-006870-f5w6fw6q 2366 21 ( ( -LRB- cord-006870-f5w6fw6q 2366 22 OR or CC cord-006870-f5w6fw6q 2366 23 , , , cord-006870-f5w6fw6q 2366 24 6.31 6.31 CD cord-006870-f5w6fw6q 2366 25 ; ; : cord-006870-f5w6fw6q 2366 26 95 95 CD cord-006870-f5w6fw6q 2366 27 % % NN cord-006870-f5w6fw6q 2366 28 CI ci NN cord-006870-f5w6fw6q 2366 29 , , , cord-006870-f5w6fw6q 2366 30 5.21 5.21 CD cord-006870-f5w6fw6q 2366 31 - - HYPH cord-006870-f5w6fw6q 2366 32 7.63 7.63 CD cord-006870-f5w6fw6q 2366 33 ) ) -RRB- cord-006870-f5w6fw6q 2366 34 , , , cord-006870-f5w6fw6q 2366 35 transient transient JJ cord-006870-f5w6fw6q 2366 36 global global JJ cord-006870-f5w6fw6q 2366 37 amnesia amnesia NN cord-006870-f5w6fw6q 2366 38 ( ( -LRB- cord-006870-f5w6fw6q 2366 39 OR or CC cord-006870-f5w6fw6q 2366 40 , , , cord-006870-f5w6fw6q 2366 41 2.71 2.71 CD cord-006870-f5w6fw6q 2366 42 ; ; : cord-006870-f5w6fw6q 2366 43 95 95 CD cord-006870-f5w6fw6q 2366 44 % % NN cord-006870-f5w6fw6q 2366 45 CI CI NNP cord-006870-f5w6fw6q 2366 46 , , , cord-006870-f5w6fw6q 2366 47 1.66 1.66 CD cord-006870-f5w6fw6q 2366 48 - - SYM cord-006870-f5w6fw6q 2366 49 4.43 4.43 CD cord-006870-f5w6fw6q 2366 50 ) ) -RRB- cord-006870-f5w6fw6q 2366 51 , , , cord-006870-f5w6fw6q 2366 52 and and CC cord-006870-f5w6fw6q 2366 53 meningoencephalitis meningoencephalitis NNP cord-006870-f5w6fw6q 2366 54 ( ( -LRB- cord-006870-f5w6fw6q 2366 55 OR or CC cord-006870-f5w6fw6q 2366 56 , , , cord-006870-f5w6fw6q 2366 57 2.36 2.36 CD cord-006870-f5w6fw6q 2366 58 ; ; : cord-006870-f5w6fw6q 2366 59 95 95 CD cord-006870-f5w6fw6q 2366 60 % % NN cord-006870-f5w6fw6q 2366 61 CI ci NN cord-006870-f5w6fw6q 2366 62 , , , cord-006870-f5w6fw6q 2366 63 1.91 1.91 CD cord-006870-f5w6fw6q 2366 64 - - SYM cord-006870-f5w6fw6q 2366 65 2.92 2.92 CD cord-006870-f5w6fw6q 2366 66 ) ) -RRB- cord-006870-f5w6fw6q 2366 67 were be VBD cord-006870-f5w6fw6q 2366 68 most most RBS cord-006870-f5w6fw6q 2366 69 strongly strongly RB cord-006870-f5w6fw6q 2366 70 associated associate VBN cord-006870-f5w6fw6q 2366 71 with with IN cord-006870-f5w6fw6q 2366 72 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2366 73 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2366 74 . . . cord-006870-f5w6fw6q 2367 1 Weaker weak JJR cord-006870-f5w6fw6q 2367 2 associations association NNS cord-006870-f5w6fw6q 2367 3 were be VBD cord-006870-f5w6fw6q 2367 4 present present JJ cord-006870-f5w6fw6q 2367 5 for for IN cord-006870-f5w6fw6q 2367 6 ischemic ischemic JJ cord-006870-f5w6fw6q 2367 7 stroke stroke NN cord-006870-f5w6fw6q 2367 8 ( ( -LRB- cord-006870-f5w6fw6q 2367 9 OR or CC cord-006870-f5w6fw6q 2367 10 , , , cord-006870-f5w6fw6q 2367 11 1.18 1.18 CD cord-006870-f5w6fw6q 2367 12 ; ; : cord-006870-f5w6fw6q 2367 13 95 95 CD cord-006870-f5w6fw6q 2367 14 % % NN cord-006870-f5w6fw6q 2367 15 CI CI NNP cord-006870-f5w6fw6q 2367 16 , , , cord-006870-f5w6fw6q 2367 17 1.08 1.08 CD cord-006870-f5w6fw6q 2367 18 - - SYM cord-006870-f5w6fw6q 2367 19 1.30 1.30 CD cord-006870-f5w6fw6q 2367 20 ) ) -RRB- cord-006870-f5w6fw6q 2367 21 and and CC cord-006870-f5w6fw6q 2367 22 migraine migraine JJ cord-006870-f5w6fw6q 2367 23 headache headache NN cord-006870-f5w6fw6q 2367 24 ( ( -LRB- cord-006870-f5w6fw6q 2367 25 OR or CC cord-006870-f5w6fw6q 2367 26 , , , cord-006870-f5w6fw6q 2367 27 1.44 1.44 CD cord-006870-f5w6fw6q 2367 28 ; ; . cord-006870-f5w6fw6q 2368 1 95 95 CD cord-006870-f5w6fw6q 2368 2 % % NN cord-006870-f5w6fw6q 2368 3 CI CI NNP cord-006870-f5w6fw6q 2368 4 , , , cord-006870-f5w6fw6q 2368 5 1.31 1.31 CD cord-006870-f5w6fw6q 2368 6 - - SYM cord-006870-f5w6fw6q 2368 7 1.59 1.59 CD cord-006870-f5w6fw6q 2368 8 ) ) -RRB- cord-006870-f5w6fw6q 2368 9 . . . cord-006870-f5w6fw6q 2369 1 Intracerebral intracerebral JJ cord-006870-f5w6fw6q 2369 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2369 3 and and CC cord-006870-f5w6fw6q 2369 4 Guillaine Guillaine NNP cord-006870-f5w6fw6q 2369 5 - - HYPH cord-006870-f5w6fw6q 2369 6 Barre Barre NNP cord-006870-f5w6fw6q 2369 7 syndrome syndrome NN cord-006870-f5w6fw6q 2369 8 were be VBD cord-006870-f5w6fw6q 2369 9 not not RB cord-006870-f5w6fw6q 2369 10 significantly significantly RB cord-006870-f5w6fw6q 2369 11 associated associate VBN cord-006870-f5w6fw6q 2369 12 with with IN cord-006870-f5w6fw6q 2369 13 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2369 14 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2369 15 . . . cord-006870-f5w6fw6q 2370 1 In in IN cord-006870-f5w6fw6q 2370 2 our -PRON- PRP$ cord-006870-f5w6fw6q 2370 3 multivariable multivariable JJ cord-006870-f5w6fw6q 2370 4 model model NN cord-006870-f5w6fw6q 2370 5 , , , cord-006870-f5w6fw6q 2370 6 female female JJ cord-006870-f5w6fw6q 2370 7 sex sex NN cord-006870-f5w6fw6q 2370 8 was be VBD cord-006870-f5w6fw6q 2370 9 significantly significantly RB cord-006870-f5w6fw6q 2370 10 associated associate VBN cord-006870-f5w6fw6q 2370 11 with with IN cord-006870-f5w6fw6q 2370 12 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2370 13 ( ( -LRB- cord-006870-f5w6fw6q 2370 14 OR or CC cord-006870-f5w6fw6q 2370 15 , , , cord-006870-f5w6fw6q 2370 16 5.09 5.09 CD cord-006870-f5w6fw6q 2370 17 ; ; : cord-006870-f5w6fw6q 2370 18 95 95 CD cord-006870-f5w6fw6q 2370 19 % % NN cord-006870-f5w6fw6q 2370 20 CI CI NNP cord-006870-f5w6fw6q 2370 21 , , , cord-006870-f5w6fw6q 2370 22 4.85 4.85 CD cord-006870-f5w6fw6q 2370 23 - - SYM cord-006870-f5w6fw6q 2370 24 5.35 5.35 CD cord-006870-f5w6fw6q 2370 25 ) ) -RRB- cord-006870-f5w6fw6q 2370 26 . . . cord-006870-f5w6fw6q 2371 1 We -PRON- PRP cord-006870-f5w6fw6q 2371 2 found find VBD cord-006870-f5w6fw6q 2371 3 associations association NNS cord-006870-f5w6fw6q 2371 4 with with IN cord-006870-f5w6fw6q 2371 5 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 2371 6 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2371 7 for for IN cord-006870-f5w6fw6q 2371 8 several several JJ cord-006870-f5w6fw6q 2371 9 acute acute JJ cord-006870-f5w6fw6q 2371 10 neurological neurological JJ cord-006870-f5w6fw6q 2371 11 diseases disease NNS cord-006870-f5w6fw6q 2371 12 besides besides IN cord-006870-f5w6fw6q 2371 13 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2371 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2371 15 . . . cord-006870-f5w6fw6q 2372 1 Gram gram NN cord-006870-f5w6fw6q 2372 2 - - HYPH cord-006870-f5w6fw6q 2372 3 Negative negative JJ cord-006870-f5w6fw6q 2372 4 Meningoventriculitis Meningoventriculitis NNP cord-006870-f5w6fw6q 2372 5 ( ( -LRB- cord-006870-f5w6fw6q 2372 6 GNMV GNMV NNP cord-006870-f5w6fw6q 2372 7 ) ) -RRB- cord-006870-f5w6fw6q 2372 8 causes cause VBZ cord-006870-f5w6fw6q 2372 9 significant significant JJ cord-006870-f5w6fw6q 2372 10 morbidity morbidity NN cord-006870-f5w6fw6q 2372 11 and and CC cord-006870-f5w6fw6q 2372 12 mortality mortality NN cord-006870-f5w6fw6q 2372 13 . . . cord-006870-f5w6fw6q 2373 1 In in IN cord-006870-f5w6fw6q 2373 2 addition addition NN cord-006870-f5w6fw6q 2373 3 to to IN cord-006870-f5w6fw6q 2373 4 intravenous intravenous JJ cord-006870-f5w6fw6q 2373 5 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2373 6 , , , cord-006870-f5w6fw6q 2373 7 intra intra JJ cord-006870-f5w6fw6q 2373 8 - - JJ cord-006870-f5w6fw6q 2373 9 thecal thecal JJ cord-006870-f5w6fw6q 2373 10 ( ( -LRB- cord-006870-f5w6fw6q 2373 11 IT it NN cord-006870-f5w6fw6q 2373 12 ) ) -RRB- cord-006870-f5w6fw6q 2373 13 or or CC cord-006870-f5w6fw6q 2373 14 intraventricular intraventricular JJ cord-006870-f5w6fw6q 2373 15 ( ( -LRB- cord-006870-f5w6fw6q 2373 16 IV IV NNP cord-006870-f5w6fw6q 2373 17 ) ) -RRB- cord-006870-f5w6fw6q 2373 18 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2373 19 may may MD cord-006870-f5w6fw6q 2373 20 be be VB cord-006870-f5w6fw6q 2373 21 used use VBN cord-006870-f5w6fw6q 2373 22 to to TO cord-006870-f5w6fw6q 2373 23 treat treat VB cord-006870-f5w6fw6q 2373 24 central central JJ cord-006870-f5w6fw6q 2373 25 nervous nervous JJ cord-006870-f5w6fw6q 2373 26 system system NN cord-006870-f5w6fw6q 2373 27 ( ( -LRB- cord-006870-f5w6fw6q 2373 28 CNS CNS NNP cord-006870-f5w6fw6q 2373 29 ) ) -RRB- cord-006870-f5w6fw6q 2373 30 gram gram NN cord-006870-f5w6fw6q 2373 31 - - HYPH cord-006870-f5w6fw6q 2373 32 negative negative JJ cord-006870-f5w6fw6q 2373 33 infections infection NNS cord-006870-f5w6fw6q 2373 34 , , , cord-006870-f5w6fw6q 2373 35 including include VBG cord-006870-f5w6fw6q 2373 36 multi multi JJ cord-006870-f5w6fw6q 2373 37 - - JJ cord-006870-f5w6fw6q 2373 38 drug drug JJ cord-006870-f5w6fw6q 2373 39 resistant resistant JJ cord-006870-f5w6fw6q 2373 40 GNMV GNMV NNS cord-006870-f5w6fw6q 2373 41 . . . cord-006870-f5w6fw6q 2374 1 There there EX cord-006870-f5w6fw6q 2374 2 are be VBP cord-006870-f5w6fw6q 2374 3 limited limited JJ cord-006870-f5w6fw6q 2374 4 studies study NNS cord-006870-f5w6fw6q 2374 5 on on IN cord-006870-f5w6fw6q 2374 6 the the DT cord-006870-f5w6fw6q 2374 7 effect effect NN cord-006870-f5w6fw6q 2374 8 of of IN cord-006870-f5w6fw6q 2374 9 direct direct JJ cord-006870-f5w6fw6q 2374 10 CNS CNS NNP cord-006870-f5w6fw6q 2374 11 administration administration NN cord-006870-f5w6fw6q 2374 12 on on IN cord-006870-f5w6fw6q 2374 13 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 2374 14 fluid fluid NN cord-006870-f5w6fw6q 2374 15 ( ( -LRB- cord-006870-f5w6fw6q 2374 16 CSF CSF NNP cord-006870-f5w6fw6q 2374 17 ) ) -RRB- cord-006870-f5w6fw6q 2374 18 cultures culture NNS cord-006870-f5w6fw6q 2374 19 , , , cord-006870-f5w6fw6q 2374 20 CSF CSF NNP cord-006870-f5w6fw6q 2374 21 routine routine JJ cord-006870-f5w6fw6q 2374 22 parameters parameter NNS cord-006870-f5w6fw6q 2374 23 and and CC cord-006870-f5w6fw6q 2374 24 other other JJ cord-006870-f5w6fw6q 2374 25 clinical clinical JJ cord-006870-f5w6fw6q 2374 26 outcomes outcome NNS cord-006870-f5w6fw6q 2374 27 . . . cord-006870-f5w6fw6q 2375 1 We -PRON- PRP cord-006870-f5w6fw6q 2375 2 conducted conduct VBD cord-006870-f5w6fw6q 2375 3 a a DT cord-006870-f5w6fw6q 2375 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2375 5 chart chart NN cord-006870-f5w6fw6q 2375 6 review review NN cord-006870-f5w6fw6q 2375 7 of of IN cord-006870-f5w6fw6q 2375 8 all all DT cord-006870-f5w6fw6q 2375 9 patients patient NNS cord-006870-f5w6fw6q 2375 10 who who WP cord-006870-f5w6fw6q 2375 11 received receive VBD cord-006870-f5w6fw6q 2375 12 IT it PRP cord-006870-f5w6fw6q 2375 13 or or CC cord-006870-f5w6fw6q 2375 14 IV IV NNP cord-006870-f5w6fw6q 2375 15 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2375 16 for for IN cord-006870-f5w6fw6q 2375 17 GNMV GNMV NNS cord-006870-f5w6fw6q 2375 18 since since IN cord-006870-f5w6fw6q 2375 19 2009 2009 CD cord-006870-f5w6fw6q 2375 20 . . . cord-006870-f5w6fw6q 2376 1 Demographics demographic NNS cord-006870-f5w6fw6q 2376 2 , , , cord-006870-f5w6fw6q 2376 3 source source NN cord-006870-f5w6fw6q 2376 4 of of IN cord-006870-f5w6fw6q 2376 5 illness illness NN cord-006870-f5w6fw6q 2376 6 , , , cord-006870-f5w6fw6q 2376 7 severity severity NN cord-006870-f5w6fw6q 2376 8 of of IN cord-006870-f5w6fw6q 2376 9 illness illness NN cord-006870-f5w6fw6q 2376 10 ( ( -LRB- cord-006870-f5w6fw6q 2376 11 SOFA SOFA NNP cord-006870-f5w6fw6q 2376 12 ) ) -RRB- cord-006870-f5w6fw6q 2376 13 , , , cord-006870-f5w6fw6q 2376 14 intravenous intravenous JJ cord-006870-f5w6fw6q 2376 15 and and CC cord-006870-f5w6fw6q 2376 16 IT IT NNP cord-006870-f5w6fw6q 2376 17 / / SYM cord-006870-f5w6fw6q 2376 18 IV IV NNP cord-006870-f5w6fw6q 2376 19 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2376 20 choice choice NN cord-006870-f5w6fw6q 2376 21 and and CC cord-006870-f5w6fw6q 2376 22 CSF CSF NNP cord-006870-f5w6fw6q 2376 23 microbiological microbiological JJ cord-006870-f5w6fw6q 2376 24 , , , cord-006870-f5w6fw6q 2376 25 drug drug NN cord-006870-f5w6fw6q 2376 26 level level NN cord-006870-f5w6fw6q 2376 27 and and CC cord-006870-f5w6fw6q 2376 28 routine routine JJ cord-006870-f5w6fw6q 2376 29 analysis analysis NN cord-006870-f5w6fw6q 2376 30 were be VBD cord-006870-f5w6fw6q 2376 31 collected collect VBN cord-006870-f5w6fw6q 2376 32 . . . cord-006870-f5w6fw6q 2377 1 Time time NN cord-006870-f5w6fw6q 2377 2 to to TO cord-006870-f5w6fw6q 2377 3 pathogen pathogen NN cord-006870-f5w6fw6q 2377 4 clearance clearance NN cord-006870-f5w6fw6q 2377 5 from from IN cord-006870-f5w6fw6q 2377 6 CSF CSF NNP cord-006870-f5w6fw6q 2377 7 culture culture NN cord-006870-f5w6fw6q 2377 8 was be VBD cord-006870-f5w6fw6q 2377 9 also also RB cord-006870-f5w6fw6q 2377 10 measured measure VBN cord-006870-f5w6fw6q 2377 11 . . . cord-006870-f5w6fw6q 2378 1 There there EX cord-006870-f5w6fw6q 2378 2 were be VBD cord-006870-f5w6fw6q 2378 3 32 32 CD cord-006870-f5w6fw6q 2378 4 inpatient inpatient JJ cord-006870-f5w6fw6q 2378 5 encounters encounter NNS cord-006870-f5w6fw6q 2378 6 where where WRB cord-006870-f5w6fw6q 2378 7 IV IV NNP cord-006870-f5w6fw6q 2378 8 / / , cord-006870-f5w6fw6q 2378 9 IT it NN cord-006870-f5w6fw6q 2378 10 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2378 11 were be VBD cord-006870-f5w6fw6q 2378 12 given give VBN cord-006870-f5w6fw6q 2378 13 for for IN cord-006870-f5w6fw6q 2378 14 GNMV GNMV NNS cord-006870-f5w6fw6q 2378 15 during during IN cord-006870-f5w6fw6q 2378 16 our -PRON- PRP$ cord-006870-f5w6fw6q 2378 17 study study NN cord-006870-f5w6fw6q 2378 18 period period NN cord-006870-f5w6fw6q 2378 19 , , , cord-006870-f5w6fw6q 2378 20 of of IN cord-006870-f5w6fw6q 2378 21 which which WDT cord-006870-f5w6fw6q 2378 22 24 24 CD cord-006870-f5w6fw6q 2378 23 were be VBD cord-006870-f5w6fw6q 2378 24 cared care VBN cord-006870-f5w6fw6q 2378 25 for for IN cord-006870-f5w6fw6q 2378 26 in in IN cord-006870-f5w6fw6q 2378 27 a a DT cord-006870-f5w6fw6q 2378 28 neurosciences neuroscience NNS cord-006870-f5w6fw6q 2378 29 intensive intensive JJ cord-006870-f5w6fw6q 2378 30 care care NN cord-006870-f5w6fw6q 2378 31 unit unit NN cord-006870-f5w6fw6q 2378 32 . . . cord-006870-f5w6fw6q 2379 1 Antibiotics antibiotic NNS cord-006870-f5w6fw6q 2379 2 utilized utilize VBN cord-006870-f5w6fw6q 2379 3 were be VBD cord-006870-f5w6fw6q 2379 4 : : : cord-006870-f5w6fw6q 2379 5 Gentamicin Gentamicin NNP cord-006870-f5w6fw6q 2379 6 ( ( -LRB- cord-006870-f5w6fw6q 2379 7 20 20 CD cord-006870-f5w6fw6q 2379 8 ) ) -RRB- cord-006870-f5w6fw6q 2379 9 , , , cord-006870-f5w6fw6q 2379 10 Colistimethate Colistimethate NNP cord-006870-f5w6fw6q 2379 11 sodium sodium NN cord-006870-f5w6fw6q 2379 12 ( ( -LRB- cord-006870-f5w6fw6q 2379 13 7 7 CD cord-006870-f5w6fw6q 2379 14 ) ) -RRB- cord-006870-f5w6fw6q 2379 15 , , . cord-006870-f5w6fw6q 2380 1 Amikacin Amikacin NNP cord-006870-f5w6fw6q 2380 2 ( ( -LRB- cord-006870-f5w6fw6q 2380 3 4 4 CD cord-006870-f5w6fw6q 2380 4 ) ) -RRB- cord-006870-f5w6fw6q 2380 5 , , , cord-006870-f5w6fw6q 2380 6 and and CC cord-006870-f5w6fw6q 2380 7 Tobramycin Tobramycin NNPS cord-006870-f5w6fw6q 2380 8 ( ( -LRB- cord-006870-f5w6fw6q 2380 9 1 1 CD cord-006870-f5w6fw6q 2380 10 ) ) -RRB- cord-006870-f5w6fw6q 2380 11 . . . cord-006870-f5w6fw6q 2381 1 The the DT cord-006870-f5w6fw6q 2381 2 most most RBS cord-006870-f5w6fw6q 2381 3 common common JJ cord-006870-f5w6fw6q 2381 4 pathogens pathogen NNS cord-006870-f5w6fw6q 2381 5 were be VBD cord-006870-f5w6fw6q 2381 6 P. P. NNP cord-006870-f5w6fw6q 2381 7 aeruginosa aeruginosa NNP cord-006870-f5w6fw6q 2381 8 ( ( -LRB- cord-006870-f5w6fw6q 2381 9 8) 8) NNP cord-006870-f5w6fw6q 2381 10 , , , cord-006870-f5w6fw6q 2381 11 K. K. NNP cord-006870-f5w6fw6q 2381 12 pneumoniae pneumoniae NN cord-006870-f5w6fw6q 2381 13 ( ( -LRB- cord-006870-f5w6fw6q 2381 14 8) 8) NNP cord-006870-f5w6fw6q 2381 15 , , , cord-006870-f5w6fw6q 2381 16 Enterobacter Enterobacter NNP cord-006870-f5w6fw6q 2381 17 sp sp NN cord-006870-f5w6fw6q 2381 18 . . . cord-006870-f5w6fw6q 2382 1 ( ( -LRB- cord-006870-f5w6fw6q 2382 2 7 7 CD cord-006870-f5w6fw6q 2382 3 ) ) -RRB- cord-006870-f5w6fw6q 2382 4 and and CC cord-006870-f5w6fw6q 2382 5 E. E. NNP cord-006870-f5w6fw6q 2382 6 coli coli NNS cord-006870-f5w6fw6q 2382 7 ( ( -LRB- cord-006870-f5w6fw6q 2382 8 5 5 CD cord-006870-f5w6fw6q 2382 9 ) ) -RRB- cord-006870-f5w6fw6q 2382 10 . . . cord-006870-f5w6fw6q 2383 1 Prior prior RB cord-006870-f5w6fw6q 2383 2 to to IN cord-006870-f5w6fw6q 2383 3 dosing dosing NN cord-006870-f5w6fw6q 2383 4 , , , cord-006870-f5w6fw6q 2383 5 median median JJ cord-006870-f5w6fw6q 2383 6 CSF CSF NNP cord-006870-f5w6fw6q 2383 7 white white JJ cord-006870-f5w6fw6q 2383 8 blood blood NN cord-006870-f5w6fw6q 2383 9 cell cell NN cord-006870-f5w6fw6q 2383 10 ( ( -LRB- cord-006870-f5w6fw6q 2383 11 WBC WBC NNP cord-006870-f5w6fw6q 2383 12 ) ) -RRB- cord-006870-f5w6fw6q 2383 13 count count NN cord-006870-f5w6fw6q 2383 14 , , , cord-006870-f5w6fw6q 2383 15 protein protein NN cord-006870-f5w6fw6q 2383 16 and and CC cord-006870-f5w6fw6q 2383 17 glucose glucose NN cord-006870-f5w6fw6q 2383 18 was be VBD cord-006870-f5w6fw6q 2383 19 2804 2804 CD cord-006870-f5w6fw6q 2383 20 / / SYM cord-006870-f5w6fw6q 2383 21 uL ul NN cord-006870-f5w6fw6q 2383 22 , , , cord-006870-f5w6fw6q 2383 23 201 201 CD cord-006870-f5w6fw6q 2383 24 mg mg NNP cord-006870-f5w6fw6q 2383 25 / / SYM cord-006870-f5w6fw6q 2383 26 dL dl NN cord-006870-f5w6fw6q 2383 27 and and CC cord-006870-f5w6fw6q 2383 28 25 25 CD cord-006870-f5w6fw6q 2383 29 mg mg NNP cord-006870-f5w6fw6q 2383 30 / / SYM cord-006870-f5w6fw6q 2383 31 dL dl NN cord-006870-f5w6fw6q 2383 32 , , , cord-006870-f5w6fw6q 2383 33 respectively respectively RB cord-006870-f5w6fw6q 2383 34 . . . cord-006870-f5w6fw6q 2384 1 IT IT NNP cord-006870-f5w6fw6q 2384 2 / / SYM cord-006870-f5w6fw6q 2384 3 IV IV NNP cord-006870-f5w6fw6q 2384 4 Antibiotics antibiotic NNS cord-006870-f5w6fw6q 2384 5 were be VBD cord-006870-f5w6fw6q 2384 6 dosed dose VBN cord-006870-f5w6fw6q 2384 7 a a DT cord-006870-f5w6fw6q 2384 8 median median NN cord-006870-f5w6fw6q 2384 9 of of IN cord-006870-f5w6fw6q 2384 10 4 4 CD cord-006870-f5w6fw6q 2384 11 times time NNS cord-006870-f5w6fw6q 2384 12 per per IN cord-006870-f5w6fw6q 2384 13 patient patient NN cord-006870-f5w6fw6q 2384 14 and and CC cord-006870-f5w6fw6q 2384 15 clearance clearance NN cord-006870-f5w6fw6q 2384 16 of of IN cord-006870-f5w6fw6q 2384 17 CSF csf NN cord-006870-f5w6fw6q 2384 18 culture culture NN cord-006870-f5w6fw6q 2384 19 occurred occur VBD cord-006870-f5w6fw6q 2384 20 in in IN cord-006870-f5w6fw6q 2384 21 a a DT cord-006870-f5w6fw6q 2384 22 median median NN cord-006870-f5w6fw6q 2384 23 of of IN cord-006870-f5w6fw6q 2384 24 5 5 CD cord-006870-f5w6fw6q 2384 25 days day NNS cord-006870-f5w6fw6q 2384 26 . . . cord-006870-f5w6fw6q 2385 1 There there EX cord-006870-f5w6fw6q 2385 2 were be VBD cord-006870-f5w6fw6q 2385 3 significant significant JJ cord-006870-f5w6fw6q 2385 4 changes change NNS cord-006870-f5w6fw6q 2385 5 in in IN cord-006870-f5w6fw6q 2385 6 CSF CSF NNP cord-006870-f5w6fw6q 2385 7 WBC WBC NNP cord-006870-f5w6fw6q 2385 8 ( ( -LRB- cord-006870-f5w6fw6q 2385 9 p p NN cord-006870-f5w6fw6q 2385 10 < < XX cord-006870-f5w6fw6q 2385 11 .001 .001 CD cord-006870-f5w6fw6q 2385 12 ) ) -RRB- cord-006870-f5w6fw6q 2385 13 , , , cord-006870-f5w6fw6q 2385 14 protein protein NN cord-006870-f5w6fw6q 2385 15 ( ( -LRB- cord-006870-f5w6fw6q 2385 16 p<.001 p<.001 JJ cord-006870-f5w6fw6q 2385 17 ) ) -RRB- cord-006870-f5w6fw6q 2385 18 and and CC cord-006870-f5w6fw6q 2385 19 glucose glucose NN cord-006870-f5w6fw6q 2385 20 ( ( -LRB- cord-006870-f5w6fw6q 2385 21 p<.001 p<.001 NNP cord-006870-f5w6fw6q 2385 22 ) ) -RRB- cord-006870-f5w6fw6q 2385 23 between between IN cord-006870-f5w6fw6q 2385 24 the the DT cord-006870-f5w6fw6q 2385 25 first first JJ cord-006870-f5w6fw6q 2385 26 and and CC cord-006870-f5w6fw6q 2385 27 last last JJ cord-006870-f5w6fw6q 2385 28 dose dose NN cord-006870-f5w6fw6q 2385 29 of of IN cord-006870-f5w6fw6q 2385 30 IV IV NNP cord-006870-f5w6fw6q 2385 31 / / , cord-006870-f5w6fw6q 2385 32 IT IT NNP cord-006870-f5w6fw6q 2385 33 antibiotics antibiotic VBZ cord-006870-f5w6fw6q 2385 34 . . . cord-006870-f5w6fw6q 2386 1 Twenty twenty CD cord-006870-f5w6fw6q 2386 2 - - HYPH cord-006870-f5w6fw6q 2386 3 five five CD cord-006870-f5w6fw6q 2386 4 ( ( -LRB- cord-006870-f5w6fw6q 2386 5 78.1 78.1 CD cord-006870-f5w6fw6q 2386 6 % % NN cord-006870-f5w6fw6q 2386 7 ) ) -RRB- cord-006870-f5w6fw6q 2386 8 patients patient NNS cord-006870-f5w6fw6q 2386 9 survived survive VBD cord-006870-f5w6fw6q 2386 10 to to TO cord-006870-f5w6fw6q 2386 11 discharge discharge VB cord-006870-f5w6fw6q 2386 12 , , , cord-006870-f5w6fw6q 2386 13 20 20 CD cord-006870-f5w6fw6q 2386 14 ( ( -LRB- cord-006870-f5w6fw6q 2386 15 62.5 62.5 CD cord-006870-f5w6fw6q 2386 16 % % NN cord-006870-f5w6fw6q 2386 17 ) ) -RRB- cord-006870-f5w6fw6q 2386 18 were be VBD cord-006870-f5w6fw6q 2386 19 confirmed confirm VBN cord-006870-f5w6fw6q 2386 20 alive alive JJ cord-006870-f5w6fw6q 2386 21 at at IN cord-006870-f5w6fw6q 2386 22 6 6 CD cord-006870-f5w6fw6q 2386 23 months month NNS cord-006870-f5w6fw6q 2386 24 . . . cord-006870-f5w6fw6q 2387 1 Patients patient NNS cord-006870-f5w6fw6q 2387 2 who who WP cord-006870-f5w6fw6q 2387 3 survived survive VBD cord-006870-f5w6fw6q 2387 4 to to TO cord-006870-f5w6fw6q 2387 5 discharge discharge VB cord-006870-f5w6fw6q 2387 6 went go VBD cord-006870-f5w6fw6q 2387 7 to to IN cord-006870-f5w6fw6q 2387 8 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 2387 9 ( ( -LRB- cord-006870-f5w6fw6q 2387 10 5 5 CD cord-006870-f5w6fw6q 2387 11 ) ) -RRB- cord-006870-f5w6fw6q 2387 12 , , , cord-006870-f5w6fw6q 2387 13 home home NN cord-006870-f5w6fw6q 2387 14 ( ( -LRB- cord-006870-f5w6fw6q 2387 15 5 5 CD cord-006870-f5w6fw6q 2387 16 ) ) -RRB- cord-006870-f5w6fw6q 2387 17 , , , cord-006870-f5w6fw6q 2387 18 long long JJ cord-006870-f5w6fw6q 2387 19 - - HYPH cord-006870-f5w6fw6q 2387 20 term term NN cord-006870-f5w6fw6q 2387 21 acute acute JJ cord-006870-f5w6fw6q 2387 22 - - HYPH cord-006870-f5w6fw6q 2387 23 care care NN cord-006870-f5w6fw6q 2387 24 ( ( -LRB- cord-006870-f5w6fw6q 2387 25 9 9 CD cord-006870-f5w6fw6q 2387 26 ) ) -RRB- cord-006870-f5w6fw6q 2387 27 and and CC cord-006870-f5w6fw6q 2387 28 skilled skilled JJ cord-006870-f5w6fw6q 2387 29 nursing nursing NN cord-006870-f5w6fw6q 2387 30 facility facility NN cord-006870-f5w6fw6q 2387 31 ( ( -LRB- cord-006870-f5w6fw6q 2387 32 6 6 CD cord-006870-f5w6fw6q 2387 33 ) ) -RRB- cord-006870-f5w6fw6q 2387 34 . . . cord-006870-f5w6fw6q 2388 1 IT it PRP cord-006870-f5w6fw6q 2388 2 and and CC cord-006870-f5w6fw6q 2388 3 IV IV NNP cord-006870-f5w6fw6q 2388 4 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2388 5 significantly significantly RB cord-006870-f5w6fw6q 2388 6 improve improve VBP cord-006870-f5w6fw6q 2388 7 CSF CSF NNP cord-006870-f5w6fw6q 2388 8 WBC WBC NNP cord-006870-f5w6fw6q 2388 9 , , , cord-006870-f5w6fw6q 2388 10 protein protein NN cord-006870-f5w6fw6q 2388 11 and and CC cord-006870-f5w6fw6q 2388 12 glucose glucose NN cord-006870-f5w6fw6q 2388 13 profiles profile NNS cord-006870-f5w6fw6q 2388 14 and and CC cord-006870-f5w6fw6q 2388 15 clear clear JJ cord-006870-f5w6fw6q 2388 16 CSF CSF NNP cord-006870-f5w6fw6q 2388 17 cultures culture NNS cord-006870-f5w6fw6q 2388 18 in in IN cord-006870-f5w6fw6q 2388 19 patients patient NNS cord-006870-f5w6fw6q 2388 20 with with IN cord-006870-f5w6fw6q 2388 21 GNMV GNMV NNP cord-006870-f5w6fw6q 2388 22 . . . cord-006870-f5w6fw6q 2389 1 IT IT NNP cord-006870-f5w6fw6q 2389 2 and and CC cord-006870-f5w6fw6q 2389 3 IV IV NNP cord-006870-f5w6fw6q 2389 4 administration administration NN cord-006870-f5w6fw6q 2389 5 may may MD cord-006870-f5w6fw6q 2389 6 provide provide VB cord-006870-f5w6fw6q 2389 7 additional additional JJ cord-006870-f5w6fw6q 2389 8 benefit benefit NN cord-006870-f5w6fw6q 2389 9 to to IN cord-006870-f5w6fw6q 2389 10 systemic systemic JJ cord-006870-f5w6fw6q 2389 11 therapy therapy NN cord-006870-f5w6fw6q 2389 12 . . . cord-006870-f5w6fw6q 2390 1 Gram gram NN cord-006870-f5w6fw6q 2390 2 - - HYPH cord-006870-f5w6fw6q 2390 3 positive positive JJ cord-006870-f5w6fw6q 2390 4 organisms organism NNS cord-006870-f5w6fw6q 2390 5 are be VBP cord-006870-f5w6fw6q 2390 6 the the DT cord-006870-f5w6fw6q 2390 7 most most RBS cord-006870-f5w6fw6q 2390 8 common common JJ cord-006870-f5w6fw6q 2390 9 cause cause NN cord-006870-f5w6fw6q 2390 10 of of IN cord-006870-f5w6fw6q 2390 11 meningo meningo NN cord-006870-f5w6fw6q 2390 12 - - HYPH cord-006870-f5w6fw6q 2390 13 ventriculitis ventriculitis NNP cord-006870-f5w6fw6q 2390 14 . . . cord-006870-f5w6fw6q 2391 1 Systemic systemic JJ cord-006870-f5w6fw6q 2391 2 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 2391 3 therapy therapy NN cord-006870-f5w6fw6q 2391 4 may may MD cord-006870-f5w6fw6q 2391 5 fail fail VB cord-006870-f5w6fw6q 2391 6 to to TO cord-006870-f5w6fw6q 2391 7 achieve achieve VB cord-006870-f5w6fw6q 2391 8 adequate adequate JJ cord-006870-f5w6fw6q 2391 9 cerebrospinal cerebrospinal NN cord-006870-f5w6fw6q 2391 10 fluid fluid NN cord-006870-f5w6fw6q 2391 11 ( ( -LRB- cord-006870-f5w6fw6q 2391 12 CSF CSF NNP cord-006870-f5w6fw6q 2391 13 ) ) -RRB- cord-006870-f5w6fw6q 2391 14 concentrations concentration NNS cord-006870-f5w6fw6q 2391 15 , , , cord-006870-f5w6fw6q 2391 16 particularly particularly RB cord-006870-f5w6fw6q 2391 17 against against IN cord-006870-f5w6fw6q 2391 18 organisms organism NNS cord-006870-f5w6fw6q 2391 19 with with IN cord-006870-f5w6fw6q 2391 20 higher high JJR cord-006870-f5w6fw6q 2391 21 minimum minimum JJ cord-006870-f5w6fw6q 2391 22 inhibitory inhibitory JJ cord-006870-f5w6fw6q 2391 23 concentrations concentration NNS cord-006870-f5w6fw6q 2391 24 , , , cord-006870-f5w6fw6q 2391 25 such such JJ cord-006870-f5w6fw6q 2391 26 as as IN cord-006870-f5w6fw6q 2391 27 MRSA MRSA NNP cord-006870-f5w6fw6q 2391 28 and and CC cord-006870-f5w6fw6q 2391 29 VRE VRE NNP cord-006870-f5w6fw6q 2391 30 . . . cord-006870-f5w6fw6q 2392 1 Direct direct JJ cord-006870-f5w6fw6q 2392 2 intraventricular intraventricular JJ cord-006870-f5w6fw6q 2392 3 ( ( -LRB- cord-006870-f5w6fw6q 2392 4 IV IV NNP cord-006870-f5w6fw6q 2392 5 ) ) -RRB- cord-006870-f5w6fw6q 2392 6 or or CC cord-006870-f5w6fw6q 2392 7 intra intra JJ cord-006870-f5w6fw6q 2392 8 - - JJ cord-006870-f5w6fw6q 2392 9 thecal thecal JJ cord-006870-f5w6fw6q 2392 10 ( ( -LRB- cord-006870-f5w6fw6q 2392 11 IT it NN cord-006870-f5w6fw6q 2392 12 ) ) -RRB- cord-006870-f5w6fw6q 2392 13 administration administration NN cord-006870-f5w6fw6q 2392 14 may may MD cord-006870-f5w6fw6q 2392 15 be be VB cord-006870-f5w6fw6q 2392 16 beneficial beneficial JJ cord-006870-f5w6fw6q 2392 17 as as IN cord-006870-f5w6fw6q 2392 18 they -PRON- PRP cord-006870-f5w6fw6q 2392 19 can can MD cord-006870-f5w6fw6q 2392 20 facilitate facilitate VB cord-006870-f5w6fw6q 2392 21 high high JJ cord-006870-f5w6fw6q 2392 22 CSF CSF NNP cord-006870-f5w6fw6q 2392 23 levels level NNS cord-006870-f5w6fw6q 2392 24 at at IN cord-006870-f5w6fw6q 2392 25 the the DT cord-006870-f5w6fw6q 2392 26 site site NN cord-006870-f5w6fw6q 2392 27 of of IN cord-006870-f5w6fw6q 2392 28 infection infection NN cord-006870-f5w6fw6q 2392 29 . . . cord-006870-f5w6fw6q 2393 1 There there EX cord-006870-f5w6fw6q 2393 2 are be VBP cord-006870-f5w6fw6q 2393 3 limited limited JJ cord-006870-f5w6fw6q 2393 4 studies study NNS cord-006870-f5w6fw6q 2393 5 on on IN cord-006870-f5w6fw6q 2393 6 the the DT cord-006870-f5w6fw6q 2393 7 effect effect NN cord-006870-f5w6fw6q 2393 8 of of IN cord-006870-f5w6fw6q 2393 9 direct direct JJ cord-006870-f5w6fw6q 2393 10 central central JJ cord-006870-f5w6fw6q 2393 11 nervous nervous JJ cord-006870-f5w6fw6q 2393 12 system system NN cord-006870-f5w6fw6q 2393 13 ( ( -LRB- cord-006870-f5w6fw6q 2393 14 CNS CNS NNP cord-006870-f5w6fw6q 2393 15 ) ) -RRB- cord-006870-f5w6fw6q 2393 16 administration administration NN cord-006870-f5w6fw6q 2393 17 of of IN cord-006870-f5w6fw6q 2393 18 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2393 19 on on IN cord-006870-f5w6fw6q 2393 20 CSF CSF NNP cord-006870-f5w6fw6q 2393 21 cultures culture NNS cord-006870-f5w6fw6q 2393 22 , , , cord-006870-f5w6fw6q 2393 23 CSF CSF NNP cord-006870-f5w6fw6q 2393 24 routine routine JJ cord-006870-f5w6fw6q 2393 25 parameters parameter NNS cord-006870-f5w6fw6q 2393 26 and and CC cord-006870-f5w6fw6q 2393 27 other other JJ cord-006870-f5w6fw6q 2393 28 clinical clinical JJ cord-006870-f5w6fw6q 2393 29 outcomes outcome NNS cord-006870-f5w6fw6q 2393 30 . . . cord-006870-f5w6fw6q 2394 1 We -PRON- PRP cord-006870-f5w6fw6q 2394 2 conducted conduct VBD cord-006870-f5w6fw6q 2394 3 a a DT cord-006870-f5w6fw6q 2394 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2394 5 chart chart NN cord-006870-f5w6fw6q 2394 6 review review NN cord-006870-f5w6fw6q 2394 7 of of IN cord-006870-f5w6fw6q 2394 8 all all DT cord-006870-f5w6fw6q 2394 9 patients patient NNS cord-006870-f5w6fw6q 2394 10 who who WP cord-006870-f5w6fw6q 2394 11 received receive VBD cord-006870-f5w6fw6q 2394 12 IT IT NNP cord-006870-f5w6fw6q 2394 13 / / SYM cord-006870-f5w6fw6q 2394 14 IV IV NNP cord-006870-f5w6fw6q 2394 15 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2394 16 for for IN cord-006870-f5w6fw6q 2394 17 grampositive grampositive NNP cord-006870-f5w6fw6q 2394 18 meningo meningo NNP cord-006870-f5w6fw6q 2394 19 - - HYPH cord-006870-f5w6fw6q 2394 20 ventriculitis ventriculitis NNP cord-006870-f5w6fw6q 2394 21 since since IN cord-006870-f5w6fw6q 2394 22 2009 2009 CD cord-006870-f5w6fw6q 2394 23 . . . cord-006870-f5w6fw6q 2395 1 Demographics demographic NNS cord-006870-f5w6fw6q 2395 2 , , , cord-006870-f5w6fw6q 2395 3 source source NN cord-006870-f5w6fw6q 2395 4 of of IN cord-006870-f5w6fw6q 2395 5 illness illness NN cord-006870-f5w6fw6q 2395 6 , , , cord-006870-f5w6fw6q 2395 7 severity severity NN cord-006870-f5w6fw6q 2395 8 of of IN cord-006870-f5w6fw6q 2395 9 illness illness NN cord-006870-f5w6fw6q 2395 10 ( ( -LRB- cord-006870-f5w6fw6q 2395 11 SOFA SOFA NNP cord-006870-f5w6fw6q 2395 12 ) ) -RRB- cord-006870-f5w6fw6q 2395 13 , , , cord-006870-f5w6fw6q 2395 14 intravenous intravenous JJ cord-006870-f5w6fw6q 2395 15 and and CC cord-006870-f5w6fw6q 2395 16 IT IT NNP cord-006870-f5w6fw6q 2395 17 / / SYM cord-006870-f5w6fw6q 2395 18 IV IV NNP cord-006870-f5w6fw6q 2395 19 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2395 20 choice choice NN cord-006870-f5w6fw6q 2395 21 and and CC cord-006870-f5w6fw6q 2395 22 CSF CSF NNP cord-006870-f5w6fw6q 2395 23 microbiological microbiological JJ cord-006870-f5w6fw6q 2395 24 , , , cord-006870-f5w6fw6q 2395 25 drug drug NN cord-006870-f5w6fw6q 2395 26 level level NN cord-006870-f5w6fw6q 2395 27 and and CC cord-006870-f5w6fw6q 2395 28 routine routine JJ cord-006870-f5w6fw6q 2395 29 analysis analysis NN cord-006870-f5w6fw6q 2395 30 were be VBD cord-006870-f5w6fw6q 2395 31 collected collect VBN cord-006870-f5w6fw6q 2395 32 . . . cord-006870-f5w6fw6q 2396 1 Time time NN cord-006870-f5w6fw6q 2396 2 to to TO cord-006870-f5w6fw6q 2396 3 pathogen pathogen NN cord-006870-f5w6fw6q 2396 4 clearance clearance NN cord-006870-f5w6fw6q 2396 5 from from IN cord-006870-f5w6fw6q 2396 6 CSF CSF NNP cord-006870-f5w6fw6q 2396 7 culture culture NN cord-006870-f5w6fw6q 2396 8 was be VBD cord-006870-f5w6fw6q 2396 9 also also RB cord-006870-f5w6fw6q 2396 10 measured measure VBN cord-006870-f5w6fw6q 2396 11 . . . cord-006870-f5w6fw6q 2397 1 There there EX cord-006870-f5w6fw6q 2397 2 were be VBD cord-006870-f5w6fw6q 2397 3 30 30 CD cord-006870-f5w6fw6q 2397 4 inpatient inpatient JJ cord-006870-f5w6fw6q 2397 5 encounters encounter NNS cord-006870-f5w6fw6q 2397 6 where where WRB cord-006870-f5w6fw6q 2397 7 IV IV NNP cord-006870-f5w6fw6q 2397 8 / / , cord-006870-f5w6fw6q 2397 9 IT it NN cord-006870-f5w6fw6q 2397 10 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2397 11 were be VBD cord-006870-f5w6fw6q 2397 12 given give VBN cord-006870-f5w6fw6q 2397 13 for for IN cord-006870-f5w6fw6q 2397 14 gram gram NN cord-006870-f5w6fw6q 2397 15 - - HYPH cord-006870-f5w6fw6q 2397 16 positive positive JJ cord-006870-f5w6fw6q 2397 17 meningoventriculitis meningoventriculitis NN cord-006870-f5w6fw6q 2397 18 during during IN cord-006870-f5w6fw6q 2397 19 our -PRON- PRP$ cord-006870-f5w6fw6q 2397 20 study study NN cord-006870-f5w6fw6q 2397 21 period period NN cord-006870-f5w6fw6q 2397 22 , , , cord-006870-f5w6fw6q 2397 23 of of IN cord-006870-f5w6fw6q 2397 24 which which WDT cord-006870-f5w6fw6q 2397 25 23 23 CD cord-006870-f5w6fw6q 2397 26 were be VBD cord-006870-f5w6fw6q 2397 27 cared care VBN cord-006870-f5w6fw6q 2397 28 for for IN cord-006870-f5w6fw6q 2397 29 in in IN cord-006870-f5w6fw6q 2397 30 a a DT cord-006870-f5w6fw6q 2397 31 neurosciences neuroscience NNS cord-006870-f5w6fw6q 2397 32 intensive intensive JJ cord-006870-f5w6fw6q 2397 33 care care NN cord-006870-f5w6fw6q 2397 34 unit unit NN cord-006870-f5w6fw6q 2397 35 . . . cord-006870-f5w6fw6q 2398 1 Antibiotics antibiotic NNS cord-006870-f5w6fw6q 2398 2 utilized utilize VBN cord-006870-f5w6fw6q 2398 3 were be VBD cord-006870-f5w6fw6q 2398 4 : : : cord-006870-f5w6fw6q 2398 5 Vancomycin Vancomycin NNP cord-006870-f5w6fw6q 2398 6 ( ( -LRB- cord-006870-f5w6fw6q 2398 7 28 28 CD cord-006870-f5w6fw6q 2398 8 ) ) -RRB- cord-006870-f5w6fw6q 2398 9 and and CC cord-006870-f5w6fw6q 2398 10 Daptomycin Daptomycin NNP cord-006870-f5w6fw6q 2398 11 ( ( -LRB- cord-006870-f5w6fw6q 2398 12 2 2 CD cord-006870-f5w6fw6q 2398 13 ) ) -RRB- cord-006870-f5w6fw6q 2398 14 . . . cord-006870-f5w6fw6q 2399 1 The the DT cord-006870-f5w6fw6q 2399 2 most most RBS cord-006870-f5w6fw6q 2399 3 common common JJ cord-006870-f5w6fw6q 2399 4 pathogens pathogen NNS cord-006870-f5w6fw6q 2399 5 were be VBD cord-006870-f5w6fw6q 2399 6 Staphylococcus Staphylococcus NNP cord-006870-f5w6fw6q 2399 7 sp sp NN cord-006870-f5w6fw6q 2399 8 . . . cord-006870-f5w6fw6q 2400 1 ( ( -LRB- cord-006870-f5w6fw6q 2400 2 15 15 CD cord-006870-f5w6fw6q 2400 3 ) ) -RRB- cord-006870-f5w6fw6q 2400 4 , , , cord-006870-f5w6fw6q 2400 5 Enterococcus Enterococcus NNP cord-006870-f5w6fw6q 2400 6 sp sp NN cord-006870-f5w6fw6q 2400 7 ( ( -LRB- cord-006870-f5w6fw6q 2400 8 5 5 CD cord-006870-f5w6fw6q 2400 9 ) ) -RRB- cord-006870-f5w6fw6q 2400 10 , , , cord-006870-f5w6fw6q 2400 11 and and CC cord-006870-f5w6fw6q 2400 12 Streptococcus Streptococcus NNP cord-006870-f5w6fw6q 2400 13 sp sp NNP cord-006870-f5w6fw6q 2400 14 ( ( -LRB- cord-006870-f5w6fw6q 2400 15 8) 8) NNP cord-006870-f5w6fw6q 2400 16 . . . cord-006870-f5w6fw6q 2401 1 Prior prior RB cord-006870-f5w6fw6q 2401 2 to to IN cord-006870-f5w6fw6q 2401 3 dosing dosing NN cord-006870-f5w6fw6q 2401 4 , , , cord-006870-f5w6fw6q 2401 5 median median JJ cord-006870-f5w6fw6q 2401 6 CSF CSF NNP cord-006870-f5w6fw6q 2401 7 white white JJ cord-006870-f5w6fw6q 2401 8 blood blood NN cord-006870-f5w6fw6q 2401 9 cell cell NN cord-006870-f5w6fw6q 2401 10 ( ( -LRB- cord-006870-f5w6fw6q 2401 11 WBC WBC NNP cord-006870-f5w6fw6q 2401 12 ) ) -RRB- cord-006870-f5w6fw6q 2401 13 count count NN cord-006870-f5w6fw6q 2401 14 , , , cord-006870-f5w6fw6q 2401 15 protein protein NN cord-006870-f5w6fw6q 2401 16 and and CC cord-006870-f5w6fw6q 2401 17 glucose glucose NN cord-006870-f5w6fw6q 2401 18 was be VBD cord-006870-f5w6fw6q 2401 19 430 430 CD cord-006870-f5w6fw6q 2401 20 / / SYM cord-006870-f5w6fw6q 2401 21 uL ul NN cord-006870-f5w6fw6q 2401 22 , , , cord-006870-f5w6fw6q 2401 23 117mg 117mg NNP cord-006870-f5w6fw6q 2401 24 / / SYM cord-006870-f5w6fw6q 2401 25 dL dl NN cord-006870-f5w6fw6q 2401 26 and and CC cord-006870-f5w6fw6q 2401 27 47mg 47mg NN cord-006870-f5w6fw6q 2401 28 / / SYM cord-006870-f5w6fw6q 2401 29 dL dl NN cord-006870-f5w6fw6q 2401 30 , , , cord-006870-f5w6fw6q 2401 31 respectively respectively RB cord-006870-f5w6fw6q 2401 32 . . . cord-006870-f5w6fw6q 2402 1 IT IT NNP cord-006870-f5w6fw6q 2402 2 / / SYM cord-006870-f5w6fw6q 2402 3 IV IV NNP cord-006870-f5w6fw6q 2402 4 Antibiotics antibiotic NNS cord-006870-f5w6fw6q 2402 5 were be VBD cord-006870-f5w6fw6q 2402 6 dosed dose VBN cord-006870-f5w6fw6q 2402 7 a a DT cord-006870-f5w6fw6q 2402 8 median median NN cord-006870-f5w6fw6q 2402 9 of of IN cord-006870-f5w6fw6q 2402 10 4 4 CD cord-006870-f5w6fw6q 2402 11 times time NNS cord-006870-f5w6fw6q 2402 12 per per IN cord-006870-f5w6fw6q 2402 13 patient patient NN cord-006870-f5w6fw6q 2402 14 and and CC cord-006870-f5w6fw6q 2402 15 clearance clearance NN cord-006870-f5w6fw6q 2402 16 of of IN cord-006870-f5w6fw6q 2402 17 CSF csf NN cord-006870-f5w6fw6q 2402 18 culture culture NN cord-006870-f5w6fw6q 2402 19 occurred occur VBD cord-006870-f5w6fw6q 2402 20 in in IN cord-006870-f5w6fw6q 2402 21 a a DT cord-006870-f5w6fw6q 2402 22 median median NN cord-006870-f5w6fw6q 2402 23 of of IN cord-006870-f5w6fw6q 2402 24 3 3 CD cord-006870-f5w6fw6q 2402 25 days day NNS cord-006870-f5w6fw6q 2402 26 . . . cord-006870-f5w6fw6q 2403 1 There there EX cord-006870-f5w6fw6q 2403 2 were be VBD cord-006870-f5w6fw6q 2403 3 significant significant JJ cord-006870-f5w6fw6q 2403 4 changes change NNS cord-006870-f5w6fw6q 2403 5 in in IN cord-006870-f5w6fw6q 2403 6 CSF CSF NNP cord-006870-f5w6fw6q 2403 7 WBC WBC NNP cord-006870-f5w6fw6q 2403 8 ( ( -LRB- cord-006870-f5w6fw6q 2403 9 p p NN cord-006870-f5w6fw6q 2403 10 < < XX cord-006870-f5w6fw6q 2403 11 .001 .001 CD cord-006870-f5w6fw6q 2403 12 ) ) -RRB- cord-006870-f5w6fw6q 2403 13 , , , cord-006870-f5w6fw6q 2403 14 protein protein NN cord-006870-f5w6fw6q 2403 15 ( ( -LRB- cord-006870-f5w6fw6q 2403 16 p<.001 p<.001 JJ cord-006870-f5w6fw6q 2403 17 ) ) -RRB- cord-006870-f5w6fw6q 2403 18 and and CC cord-006870-f5w6fw6q 2403 19 glucose glucose NN cord-006870-f5w6fw6q 2403 20 ( ( -LRB- cord-006870-f5w6fw6q 2403 21 p=.045 p=.045 NN cord-006870-f5w6fw6q 2403 22 ) ) -RRB- cord-006870-f5w6fw6q 2403 23 between between IN cord-006870-f5w6fw6q 2403 24 the the DT cord-006870-f5w6fw6q 2403 25 first first JJ cord-006870-f5w6fw6q 2403 26 and and CC cord-006870-f5w6fw6q 2403 27 last last JJ cord-006870-f5w6fw6q 2403 28 dose dose NN cord-006870-f5w6fw6q 2403 29 of of IN cord-006870-f5w6fw6q 2403 30 IV IV NNP cord-006870-f5w6fw6q 2403 31 / / , cord-006870-f5w6fw6q 2403 32 IT IT NNP cord-006870-f5w6fw6q 2403 33 antibiotics antibiotic VBZ cord-006870-f5w6fw6q 2403 34 . . . cord-006870-f5w6fw6q 2404 1 Twenty twenty CD cord-006870-f5w6fw6q 2404 2 - - HYPH cord-006870-f5w6fw6q 2404 3 nine nine CD cord-006870-f5w6fw6q 2404 4 ( ( -LRB- cord-006870-f5w6fw6q 2404 5 96.7 96.7 CD cord-006870-f5w6fw6q 2404 6 % % NN cord-006870-f5w6fw6q 2404 7 ) ) -RRB- cord-006870-f5w6fw6q 2404 8 patients patient NNS cord-006870-f5w6fw6q 2404 9 survived survive VBD cord-006870-f5w6fw6q 2404 10 to to TO cord-006870-f5w6fw6q 2404 11 discharge discharge VB cord-006870-f5w6fw6q 2404 12 , , , cord-006870-f5w6fw6q 2404 13 19 19 CD cord-006870-f5w6fw6q 2404 14 ( ( -LRB- cord-006870-f5w6fw6q 2404 15 63.3 63.3 CD cord-006870-f5w6fw6q 2404 16 % % NN cord-006870-f5w6fw6q 2404 17 ) ) -RRB- cord-006870-f5w6fw6q 2404 18 were be VBD cord-006870-f5w6fw6q 2404 19 confirmed confirm VBN cord-006870-f5w6fw6q 2404 20 alive alive JJ cord-006870-f5w6fw6q 2404 21 at at IN cord-006870-f5w6fw6q 2404 22 6 6 CD cord-006870-f5w6fw6q 2404 23 months month NNS cord-006870-f5w6fw6q 2404 24 . . . cord-006870-f5w6fw6q 2405 1 IT it PRP cord-006870-f5w6fw6q 2405 2 and and CC cord-006870-f5w6fw6q 2405 3 IV IV NNP cord-006870-f5w6fw6q 2405 4 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2405 5 significantly significantly RB cord-006870-f5w6fw6q 2405 6 improve improve VBP cord-006870-f5w6fw6q 2405 7 CSF CSF NNP cord-006870-f5w6fw6q 2405 8 WBC WBC NNP cord-006870-f5w6fw6q 2405 9 , , , cord-006870-f5w6fw6q 2405 10 protein protein NN cord-006870-f5w6fw6q 2405 11 and and CC cord-006870-f5w6fw6q 2405 12 glucose glucose NN cord-006870-f5w6fw6q 2405 13 profiles profile NNS cord-006870-f5w6fw6q 2405 14 and and CC cord-006870-f5w6fw6q 2405 15 clear clear JJ cord-006870-f5w6fw6q 2405 16 CSF CSF NNP cord-006870-f5w6fw6q 2405 17 cultures culture NNS cord-006870-f5w6fw6q 2405 18 in in IN cord-006870-f5w6fw6q 2405 19 patients patient NNS cord-006870-f5w6fw6q 2405 20 with with IN cord-006870-f5w6fw6q 2405 21 gram gram JJ cord-006870-f5w6fw6q 2405 22 - - HYPH cord-006870-f5w6fw6q 2405 23 positive positive JJ cord-006870-f5w6fw6q 2405 24 meningo meningo NN cord-006870-f5w6fw6q 2405 25 - - HYPH cord-006870-f5w6fw6q 2405 26 ventriculitis ventriculitis NNP cord-006870-f5w6fw6q 2405 27 . . . cord-006870-f5w6fw6q 2406 1 IT IT NNP cord-006870-f5w6fw6q 2406 2 and and CC cord-006870-f5w6fw6q 2406 3 IV IV NNP cord-006870-f5w6fw6q 2406 4 administration administration NN cord-006870-f5w6fw6q 2406 5 may may MD cord-006870-f5w6fw6q 2406 6 provide provide VB cord-006870-f5w6fw6q 2406 7 additional additional JJ cord-006870-f5w6fw6q 2406 8 benefit benefit NN cord-006870-f5w6fw6q 2406 9 to to IN cord-006870-f5w6fw6q 2406 10 systemic systemic JJ cord-006870-f5w6fw6q 2406 11 therapy therapy NN cord-006870-f5w6fw6q 2406 12 . . . cord-006870-f5w6fw6q 2407 1 Use use NN cord-006870-f5w6fw6q 2407 2 of of IN cord-006870-f5w6fw6q 2407 3 prothrombin prothrombin NN cord-006870-f5w6fw6q 2407 4 complex complex NN cord-006870-f5w6fw6q 2407 5 concentrate concentrate NN cord-006870-f5w6fw6q 2407 6 ( ( -LRB- cord-006870-f5w6fw6q 2407 7 PCC PCC NNP cord-006870-f5w6fw6q 2407 8 ) ) -RRB- cord-006870-f5w6fw6q 2407 9 for for IN cord-006870-f5w6fw6q 2407 10 urgent urgent JJ cord-006870-f5w6fw6q 2407 11 reversal reversal NN cord-006870-f5w6fw6q 2407 12 of of IN cord-006870-f5w6fw6q 2407 13 anticoagulant anticoagulant JJ cord-006870-f5w6fw6q 2407 14 associated associate VBN cord-006870-f5w6fw6q 2407 15 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 2407 16 is be VBZ cord-006870-f5w6fw6q 2407 17 increasing increase VBG cord-006870-f5w6fw6q 2407 18 , , , cord-006870-f5w6fw6q 2407 19 and and CC cord-006870-f5w6fw6q 2407 20 at at IN cord-006870-f5w6fw6q 2407 21 the the DT cord-006870-f5w6fw6q 2407 22 University University NNP cord-006870-f5w6fw6q 2407 23 of of IN cord-006870-f5w6fw6q 2407 24 Illinois Illinois NNP cord-006870-f5w6fw6q 2407 25 Hospital Hospital NNP cord-006870-f5w6fw6q 2407 26 ( ( -LRB- cord-006870-f5w6fw6q 2407 27 UIH UIH NNP cord-006870-f5w6fw6q 2407 28 ) ) -RRB- cord-006870-f5w6fw6q 2407 29 , , , cord-006870-f5w6fw6q 2407 30 an an DT cord-006870-f5w6fw6q 2407 31 anti anti JJ cord-006870-f5w6fw6q 2407 32 - - JJ cord-006870-f5w6fw6q 2407 33 thrombotic thrombotic JJ cord-006870-f5w6fw6q 2407 34 reversal reversal NN cord-006870-f5w6fw6q 2407 35 guideline guideline NN cord-006870-f5w6fw6q 2407 36 was be VBD cord-006870-f5w6fw6q 2407 37 developed develop VBN cord-006870-f5w6fw6q 2407 38 in in IN cord-006870-f5w6fw6q 2407 39 May May NNP cord-006870-f5w6fw6q 2407 40 2016 2016 CD cord-006870-f5w6fw6q 2407 41 in in IN cord-006870-f5w6fw6q 2407 42 order order NN cord-006870-f5w6fw6q 2407 43 to to TO cord-006870-f5w6fw6q 2407 44 assist assist VB cord-006870-f5w6fw6q 2407 45 licensed licensed JJ cord-006870-f5w6fw6q 2407 46 practitioners practitioner NNS cord-006870-f5w6fw6q 2407 47 in in IN cord-006870-f5w6fw6q 2407 48 choosing choose VBG cord-006870-f5w6fw6q 2407 49 the the DT cord-006870-f5w6fw6q 2407 50 appropriate appropriate JJ cord-006870-f5w6fw6q 2407 51 reversal reversal NN cord-006870-f5w6fw6q 2407 52 agent agent NN cord-006870-f5w6fw6q 2407 53 , , , cord-006870-f5w6fw6q 2407 54 optimal optimal JJ cord-006870-f5w6fw6q 2407 55 dosing dosing NN cord-006870-f5w6fw6q 2407 56 , , , cord-006870-f5w6fw6q 2407 57 and and CC cord-006870-f5w6fw6q 2407 58 improve improve VB cord-006870-f5w6fw6q 2407 59 timely timely JJ cord-006870-f5w6fw6q 2407 60 administration administration NN cord-006870-f5w6fw6q 2407 61 PCC PCC NNP cord-006870-f5w6fw6q 2407 62 . . . cord-006870-f5w6fw6q 2408 1 The the DT cord-006870-f5w6fw6q 2408 2 current current JJ cord-006870-f5w6fw6q 2408 3 study study NN cord-006870-f5w6fw6q 2408 4 examined examine VBD cord-006870-f5w6fw6q 2408 5 the the DT cord-006870-f5w6fw6q 2408 6 safety safety NN cord-006870-f5w6fw6q 2408 7 and and CC cord-006870-f5w6fw6q 2408 8 efficacy efficacy NN cord-006870-f5w6fw6q 2408 9 of of IN cord-006870-f5w6fw6q 2408 10 PCC PCC NNP cord-006870-f5w6fw6q 2408 11 used use VBN cord-006870-f5w6fw6q 2408 12 for for IN cord-006870-f5w6fw6q 2408 13 the the DT cord-006870-f5w6fw6q 2408 14 urgent urgent JJ cord-006870-f5w6fw6q 2408 15 reversal reversal NN cord-006870-f5w6fw6q 2408 16 of of IN cord-006870-f5w6fw6q 2408 17 anticoagulant anticoagulant JJ cord-006870-f5w6fw6q 2408 18 associated associate VBN cord-006870-f5w6fw6q 2408 19 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 2408 20 before before IN cord-006870-f5w6fw6q 2408 21 and and CC cord-006870-f5w6fw6q 2408 22 after after IN cord-006870-f5w6fw6q 2408 23 the the DT cord-006870-f5w6fw6q 2408 24 development development NN cord-006870-f5w6fw6q 2408 25 of of IN cord-006870-f5w6fw6q 2408 26 the the DT cord-006870-f5w6fw6q 2408 27 anti anti JJ cord-006870-f5w6fw6q 2408 28 - - JJ cord-006870-f5w6fw6q 2408 29 thrombotic thrombotic JJ cord-006870-f5w6fw6q 2408 30 reversal reversal NN cord-006870-f5w6fw6q 2408 31 guideline guideline NN cord-006870-f5w6fw6q 2408 32 . . . cord-006870-f5w6fw6q 2409 1 This this DT cord-006870-f5w6fw6q 2409 2 was be VBD cord-006870-f5w6fw6q 2409 3 a a DT cord-006870-f5w6fw6q 2409 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2409 5 chart chart NN cord-006870-f5w6fw6q 2409 6 review review NN cord-006870-f5w6fw6q 2409 7 of of IN cord-006870-f5w6fw6q 2409 8 adult adult NN cord-006870-f5w6fw6q 2409 9 patients patient NNS cord-006870-f5w6fw6q 2409 10 who who WP cord-006870-f5w6fw6q 2409 11 received receive VBD cord-006870-f5w6fw6q 2409 12 PCC PCC NNP cord-006870-f5w6fw6q 2409 13 as as IN cord-006870-f5w6fw6q 2409 14 the the DT cord-006870-f5w6fw6q 2409 15 only only JJ cord-006870-f5w6fw6q 2409 16 hemostatic hemostatic JJ cord-006870-f5w6fw6q 2409 17 agent agent NN cord-006870-f5w6fw6q 2409 18 at at IN cord-006870-f5w6fw6q 2409 19 the the DT cord-006870-f5w6fw6q 2409 20 UIH UIH NNP cord-006870-f5w6fw6q 2409 21 from from IN cord-006870-f5w6fw6q 2409 22 Jan Jan NNP cord-006870-f5w6fw6q 2409 23 2008 2008 CD cord-006870-f5w6fw6q 2409 24 to to IN cord-006870-f5w6fw6q 2409 25 April April NNP cord-006870-f5w6fw6q 2409 26 2017 2017 CD cord-006870-f5w6fw6q 2409 27 . . . cord-006870-f5w6fw6q 2410 1 The the DT cord-006870-f5w6fw6q 2410 2 primary primary JJ cord-006870-f5w6fw6q 2410 3 endpoint endpoint NN cord-006870-f5w6fw6q 2410 4 was be VBD cord-006870-f5w6fw6q 2410 5 hemostasis hemostasis NN cord-006870-f5w6fw6q 2410 6 and and CC cord-006870-f5w6fw6q 2410 7 secondary secondary JJ cord-006870-f5w6fw6q 2410 8 endpoints endpoint NNS cord-006870-f5w6fw6q 2410 9 included include VBD cord-006870-f5w6fw6q 2410 10 thromboembolic thromboembolic JJ cord-006870-f5w6fw6q 2410 11 events event NNS cord-006870-f5w6fw6q 2410 12 and and CC cord-006870-f5w6fw6q 2410 13 time time NN cord-006870-f5w6fw6q 2410 14 to to IN cord-006870-f5w6fw6q 2410 15 PCC PCC NNP cord-006870-f5w6fw6q 2410 16 administration administration NN cord-006870-f5w6fw6q 2410 17 . . . cord-006870-f5w6fw6q 2411 1 There there EX cord-006870-f5w6fw6q 2411 2 were be VBD cord-006870-f5w6fw6q 2411 3 21 21 CD cord-006870-f5w6fw6q 2411 4 and and CC cord-006870-f5w6fw6q 2411 5 17 17 CD cord-006870-f5w6fw6q 2411 6 patients patient NNS cord-006870-f5w6fw6q 2411 7 who who WP cord-006870-f5w6fw6q 2411 8 received receive VBD cord-006870-f5w6fw6q 2411 9 PCC PCC NNP cord-006870-f5w6fw6q 2411 10 before before RB cord-006870-f5w6fw6q 2411 11 and and CC cord-006870-f5w6fw6q 2411 12 after after IN cord-006870-f5w6fw6q 2411 13 the the DT cord-006870-f5w6fw6q 2411 14 anti anti JJ cord-006870-f5w6fw6q 2411 15 - - JJ cord-006870-f5w6fw6q 2411 16 thrombotic thrombotic JJ cord-006870-f5w6fw6q 2411 17 reversal reversal NN cord-006870-f5w6fw6q 2411 18 guideline guideline NN cord-006870-f5w6fw6q 2411 19 , , , cord-006870-f5w6fw6q 2411 20 respectively respectively RB cord-006870-f5w6fw6q 2411 21 . . . cord-006870-f5w6fw6q 2412 1 Frequent frequent JJ cord-006870-f5w6fw6q 2412 2 cause cause NN cord-006870-f5w6fw6q 2412 3 of of IN cord-006870-f5w6fw6q 2412 4 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 2412 5 was be VBD cord-006870-f5w6fw6q 2412 6 warfarin warfarin JJ cord-006870-f5w6fw6q 2412 7 ( ( -LRB- cord-006870-f5w6fw6q 2412 8 81 81 CD cord-006870-f5w6fw6q 2412 9 % % NN cord-006870-f5w6fw6q 2412 10 and and CC cord-006870-f5w6fw6q 2412 11 76 76 CD cord-006870-f5w6fw6q 2412 12 % % NN cord-006870-f5w6fw6q 2412 13 , , , cord-006870-f5w6fw6q 2412 14 respectively respectively RB cord-006870-f5w6fw6q 2412 15 ) ) -RRB- cord-006870-f5w6fw6q 2412 16 , , , cord-006870-f5w6fw6q 2412 17 and and CC cord-006870-f5w6fw6q 2412 18 frequent frequent JJ cord-006870-f5w6fw6q 2412 19 indication indication NN cord-006870-f5w6fw6q 2412 20 for for IN cord-006870-f5w6fw6q 2412 21 PCC PCC NNP cord-006870-f5w6fw6q 2412 22 was be VBD cord-006870-f5w6fw6q 2412 23 acute acute JJ cord-006870-f5w6fw6q 2412 24 intracranial intracranial JJ cord-006870-f5w6fw6q 2412 25 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2412 26 ( ( -LRB- cord-006870-f5w6fw6q 2412 27 81 81 CD cord-006870-f5w6fw6q 2412 28 % % NN cord-006870-f5w6fw6q 2412 29 and and CC cord-006870-f5w6fw6q 2412 30 76 76 CD cord-006870-f5w6fw6q 2412 31 % % NN cord-006870-f5w6fw6q 2412 32 , , , cord-006870-f5w6fw6q 2412 33 respectively respectively RB cord-006870-f5w6fw6q 2412 34 ) ) -RRB- cord-006870-f5w6fw6q 2412 35 . . . cord-006870-f5w6fw6q 2413 1 3-factor 3-factor CD cord-006870-f5w6fw6q 2413 2 PCC PCC NNP cord-006870-f5w6fw6q 2413 3 was be VBD cord-006870-f5w6fw6q 2413 4 more more RBR cord-006870-f5w6fw6q 2413 5 frequently frequently RB cord-006870-f5w6fw6q 2413 6 used use VBN cord-006870-f5w6fw6q 2413 7 before before IN cord-006870-f5w6fw6q 2413 8 the the DT cord-006870-f5w6fw6q 2413 9 guideline guideline NN cord-006870-f5w6fw6q 2413 10 and and CC cord-006870-f5w6fw6q 2413 11 4-factor 4-factor CD cord-006870-f5w6fw6q 2414 1 PCC PCC NNP cord-006870-f5w6fw6q 2414 2 was be VBD cord-006870-f5w6fw6q 2414 3 more more RBR cord-006870-f5w6fw6q 2414 4 frequently frequently RB cord-006870-f5w6fw6q 2414 5 used use VBN cord-006870-f5w6fw6q 2414 6 after after IN cord-006870-f5w6fw6q 2414 7 the the DT cord-006870-f5w6fw6q 2414 8 guideline guideline NN cord-006870-f5w6fw6q 2414 9 . . . cord-006870-f5w6fw6q 2415 1 In in IN cord-006870-f5w6fw6q 2415 2 patients patient NNS cord-006870-f5w6fw6q 2415 3 presenting present VBG cord-006870-f5w6fw6q 2415 4 with with IN cord-006870-f5w6fw6q 2415 5 warfarin warfarin NN cord-006870-f5w6fw6q 2415 6 induced induce VBN cord-006870-f5w6fw6q 2415 7 major major JJ cord-006870-f5w6fw6q 2415 8 bleeding bleeding NN cord-006870-f5w6fw6q 2415 9 , , , cord-006870-f5w6fw6q 2415 10 target target VB cord-006870-f5w6fw6q 2415 11 INR INR NNP cord-006870-f5w6fw6q 2415 12 < < XX cord-006870-f5w6fw6q 2415 13 1.4 1.4 CD cord-006870-f5w6fw6q 2415 14 was be VBD cord-006870-f5w6fw6q 2415 15 achieved achieve VBN cord-006870-f5w6fw6q 2415 16 in in IN cord-006870-f5w6fw6q 2415 17 71 71 CD cord-006870-f5w6fw6q 2415 18 % % NN cord-006870-f5w6fw6q 2415 19 and and CC cord-006870-f5w6fw6q 2415 20 62 62 CD cord-006870-f5w6fw6q 2415 21 % % NN cord-006870-f5w6fw6q 2415 22 of of IN cord-006870-f5w6fw6q 2415 23 these these DT cord-006870-f5w6fw6q 2415 24 patients patient NNS cord-006870-f5w6fw6q 2415 25 before before IN cord-006870-f5w6fw6q 2415 26 and and CC cord-006870-f5w6fw6q 2415 27 after after IN cord-006870-f5w6fw6q 2415 28 the the DT cord-006870-f5w6fw6q 2415 29 guideline guideline NN cord-006870-f5w6fw6q 2415 30 , , , cord-006870-f5w6fw6q 2415 31 respectively respectively RB cord-006870-f5w6fw6q 2415 32 . . . cord-006870-f5w6fw6q 2416 1 Clinical clinical JJ cord-006870-f5w6fw6q 2416 2 assessment assessment NN cord-006870-f5w6fw6q 2416 3 of of IN cord-006870-f5w6fw6q 2416 4 bleeding bleed VBG cord-006870-f5w6fw6q 2416 5 cessation cessation NN cord-006870-f5w6fw6q 2416 6 from from IN cord-006870-f5w6fw6q 2416 7 direct direct JJ cord-006870-f5w6fw6q 2416 8 oral oral JJ cord-006870-f5w6fw6q 2416 9 anticoagulant anticoagulant NN cord-006870-f5w6fw6q 2417 1 ( ( -LRB- cord-006870-f5w6fw6q 2417 2 DOAC DOAC NNP cord-006870-f5w6fw6q 2417 3 ) ) -RRB- cord-006870-f5w6fw6q 2417 4 therapy therapy NN cord-006870-f5w6fw6q 2417 5 was be VBD cord-006870-f5w6fw6q 2417 6 difficult difficult JJ cord-006870-f5w6fw6q 2417 7 to to TO cord-006870-f5w6fw6q 2417 8 assess assess VB cord-006870-f5w6fw6q 2417 9 . . . cord-006870-f5w6fw6q 2418 1 Thromboembolic Thromboembolic NNP cord-006870-f5w6fw6q 2418 2 event event NN cord-006870-f5w6fw6q 2418 3 was be VBD cord-006870-f5w6fw6q 2418 4 observed observe VBN cord-006870-f5w6fw6q 2418 5 in in IN cord-006870-f5w6fw6q 2418 6 38 38 CD cord-006870-f5w6fw6q 2418 7 % % NN cord-006870-f5w6fw6q 2418 8 and and CC cord-006870-f5w6fw6q 2418 9 6 6 CD cord-006870-f5w6fw6q 2418 10 % % NN cord-006870-f5w6fw6q 2418 11 of of IN cord-006870-f5w6fw6q 2418 12 the the DT cord-006870-f5w6fw6q 2418 13 patients patient NNS cord-006870-f5w6fw6q 2418 14 , , , cord-006870-f5w6fw6q 2418 15 respectively respectively RB cord-006870-f5w6fw6q 2418 16 . . . cord-006870-f5w6fw6q 2419 1 Median median JJ cord-006870-f5w6fw6q 2419 2 time time NN cord-006870-f5w6fw6q 2419 3 to to IN cord-006870-f5w6fw6q 2419 4 PCC PCC NNP cord-006870-f5w6fw6q 2419 5 administration administration NN cord-006870-f5w6fw6q 2419 6 from from IN cord-006870-f5w6fw6q 2419 7 its -PRON- PRP$ cord-006870-f5w6fw6q 2419 8 initial initial JJ cord-006870-f5w6fw6q 2419 9 order order NN cord-006870-f5w6fw6q 2419 10 was be VBD cord-006870-f5w6fw6q 2419 11 107 107 CD cord-006870-f5w6fw6q 2419 12 minutes minute NNS cord-006870-f5w6fw6q 2419 13 and and CC cord-006870-f5w6fw6q 2419 14 80 80 CD cord-006870-f5w6fw6q 2419 15 minutes minute NNS cord-006870-f5w6fw6q 2419 16 , , , cord-006870-f5w6fw6q 2419 17 respectively respectively RB cord-006870-f5w6fw6q 2419 18 . . . cord-006870-f5w6fw6q 2420 1 Hemostasis Hemostasis NNP cord-006870-f5w6fw6q 2420 2 was be VBD cord-006870-f5w6fw6q 2420 3 similarly similarly RB cord-006870-f5w6fw6q 2420 4 observed observe VBN cord-006870-f5w6fw6q 2420 5 in in IN cord-006870-f5w6fw6q 2420 6 the the DT cord-006870-f5w6fw6q 2420 7 warfarin warfarin NNP cord-006870-f5w6fw6q 2420 8 group group NN cord-006870-f5w6fw6q 2420 9 before before IN cord-006870-f5w6fw6q 2420 10 and and CC cord-006870-f5w6fw6q 2420 11 after after IN cord-006870-f5w6fw6q 2420 12 the the DT cord-006870-f5w6fw6q 2420 13 development development NN cord-006870-f5w6fw6q 2420 14 of of IN cord-006870-f5w6fw6q 2420 15 reversal reversal NN cord-006870-f5w6fw6q 2420 16 guideline guideline NN cord-006870-f5w6fw6q 2420 17 , , , cord-006870-f5w6fw6q 2420 18 but but CC cord-006870-f5w6fw6q 2420 19 more more JJR cord-006870-f5w6fw6q 2420 20 thromboembolic thromboembolic JJ cord-006870-f5w6fw6q 2420 21 events event NNS cord-006870-f5w6fw6q 2420 22 were be VBD cord-006870-f5w6fw6q 2420 23 observed observe VBN cord-006870-f5w6fw6q 2420 24 before before IN cord-006870-f5w6fw6q 2420 25 the the DT cord-006870-f5w6fw6q 2420 26 reversal reversal NN cord-006870-f5w6fw6q 2420 27 guideline guideline NN cord-006870-f5w6fw6q 2420 28 . . . cord-006870-f5w6fw6q 2421 1 In in IN cord-006870-f5w6fw6q 2421 2 order order NN cord-006870-f5w6fw6q 2421 3 to to TO cord-006870-f5w6fw6q 2421 4 further further RB cord-006870-f5w6fw6q 2421 5 reduce reduce VB cord-006870-f5w6fw6q 2421 6 the the DT cord-006870-f5w6fw6q 2421 7 PCC PCC NNP cord-006870-f5w6fw6q 2421 8 administration administration NN cord-006870-f5w6fw6q 2421 9 time time NN cord-006870-f5w6fw6q 2421 10 , , , cord-006870-f5w6fw6q 2421 11 a a DT cord-006870-f5w6fw6q 2421 12 change change NN cord-006870-f5w6fw6q 2421 13 in in IN cord-006870-f5w6fw6q 2421 14 workflow workflow NN cord-006870-f5w6fw6q 2421 15 has have VBZ cord-006870-f5w6fw6q 2421 16 been be VBN cord-006870-f5w6fw6q 2421 17 made make VBN cord-006870-f5w6fw6q 2421 18 to to TO cord-006870-f5w6fw6q 2421 19 administer administer VB cord-006870-f5w6fw6q 2421 20 PCC PCC NNP cord-006870-f5w6fw6q 2421 21 in in IN cord-006870-f5w6fw6q 2421 22 timely timely JJ cord-006870-f5w6fw6q 2421 23 manner manner NN cord-006870-f5w6fw6q 2421 24 . . . cord-006870-f5w6fw6q 2422 1 Dexmedetomidine Dexmedetomidine NNP cord-006870-f5w6fw6q 2422 2 , , , cord-006870-f5w6fw6q 2422 3 a a DT cord-006870-f5w6fw6q 2422 4 selective selective JJ cord-006870-f5w6fw6q 2422 5 alpha-2 alpha-2 NN cord-006870-f5w6fw6q 2422 6 adrenoreceptor adrenoreceptor NN cord-006870-f5w6fw6q 2422 7 agonist agonist NN cord-006870-f5w6fw6q 2422 8 inhibiting inhibit VBG cord-006870-f5w6fw6q 2422 9 sympathetic sympathetic JJ cord-006870-f5w6fw6q 2422 10 neuronal neuronal JJ cord-006870-f5w6fw6q 2422 11 activity activity NN cord-006870-f5w6fw6q 2422 12 , , , cord-006870-f5w6fw6q 2422 13 is be VBZ cord-006870-f5w6fw6q 2422 14 a a DT cord-006870-f5w6fw6q 2422 15 mild mild JJ cord-006870-f5w6fw6q 2422 16 sedation sedation NN cord-006870-f5w6fw6q 2422 17 agent agent NN cord-006870-f5w6fw6q 2422 18 . . . cord-006870-f5w6fw6q 2423 1 Two two CD cord-006870-f5w6fw6q 2423 2 recent recent JJ cord-006870-f5w6fw6q 2423 3 case case NN cord-006870-f5w6fw6q 2423 4 reports report NNS cord-006870-f5w6fw6q 2423 5 showed show VBD cord-006870-f5w6fw6q 2423 6 reduced reduce VBN cord-006870-f5w6fw6q 2423 7 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 2423 8 ( ( -LRB- cord-006870-f5w6fw6q 2423 9 NE NE NNP cord-006870-f5w6fw6q 2423 10 ) ) -RRB- cord-006870-f5w6fw6q 2423 11 requirement requirement NN cord-006870-f5w6fw6q 2423 12 in in IN cord-006870-f5w6fw6q 2423 13 septic septic JJ cord-006870-f5w6fw6q 2423 14 shock shock NN cord-006870-f5w6fw6q 2423 15 with with IN cord-006870-f5w6fw6q 2423 16 clonidine clonidine NN cord-006870-f5w6fw6q 2423 17 , , , cord-006870-f5w6fw6q 2423 18 a a DT cord-006870-f5w6fw6q 2423 19 less less RBR cord-006870-f5w6fw6q 2423 20 selective selective JJ cord-006870-f5w6fw6q 2423 21 alpha-2 alpha-2 NN cord-006870-f5w6fw6q 2423 22 agonist agonist NN cord-006870-f5w6fw6q 2423 23 . . . cord-006870-f5w6fw6q 2424 1 Increased increase VBN cord-006870-f5w6fw6q 2424 2 vasopressor vasopressor NN cord-006870-f5w6fw6q 2424 3 responsiveness responsiveness NN cord-006870-f5w6fw6q 2424 4 ( ( -LRB- cord-006870-f5w6fw6q 2424 5 VR VR NNP cord-006870-f5w6fw6q 2424 6 ) ) -RRB- cord-006870-f5w6fw6q 2424 7 was be VBD cord-006870-f5w6fw6q 2424 8 also also RB cord-006870-f5w6fw6q 2424 9 observed observe VBN cord-006870-f5w6fw6q 2424 10 with with IN cord-006870-f5w6fw6q 2424 11 dexmedetomidine dexmedetomidine NN cord-006870-f5w6fw6q 2424 12 in in IN cord-006870-f5w6fw6q 2424 13 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 2424 14 surgical surgical JJ cord-006870-f5w6fw6q 2424 15 settings setting NNS cord-006870-f5w6fw6q 2424 16 . . . cord-006870-f5w6fw6q 2425 1 Sympatholytic sympatholytic JJ cord-006870-f5w6fw6q 2425 2 effects effect NNS cord-006870-f5w6fw6q 2425 3 of of IN cord-006870-f5w6fw6q 2425 4 the the DT cord-006870-f5w6fw6q 2425 5 alpha-2 alpha-2 NN cord-006870-f5w6fw6q 2425 6 agonists agonist NNS cord-006870-f5w6fw6q 2425 7 reverse reverse VBP cord-006870-f5w6fw6q 2425 8 vascular vascular JJ cord-006870-f5w6fw6q 2425 9 desensitization desensitization NN cord-006870-f5w6fw6q 2425 10 due due IN cord-006870-f5w6fw6q 2425 11 to to IN cord-006870-f5w6fw6q 2425 12 high high JJ cord-006870-f5w6fw6q 2425 13 levels level NNS cord-006870-f5w6fw6q 2425 14 of of IN cord-006870-f5w6fw6q 2425 15 sympathetic sympathetic JJ cord-006870-f5w6fw6q 2425 16 activity activity NN cord-006870-f5w6fw6q 2425 17 in in IN cord-006870-f5w6fw6q 2425 18 sepsis sepsis NN cord-006870-f5w6fw6q 2425 19 . . . cord-006870-f5w6fw6q 2426 1 Depletion depletion NN cord-006870-f5w6fw6q 2426 2 of of IN cord-006870-f5w6fw6q 2426 3 intra intra JJ cord-006870-f5w6fw6q 2426 4 - - JJ cord-006870-f5w6fw6q 2426 5 neuronal neuronal JJ cord-006870-f5w6fw6q 2426 6 catecholamines catecholamine NNS cord-006870-f5w6fw6q 2426 7 with with IN cord-006870-f5w6fw6q 2426 8 reserpine reserpine NN cord-006870-f5w6fw6q 2426 9 has have VBZ cord-006870-f5w6fw6q 2426 10 shown show VBN cord-006870-f5w6fw6q 2426 11 to to TO cord-006870-f5w6fw6q 2426 12 increase increase VB cord-006870-f5w6fw6q 2426 13 VR VR NNP cord-006870-f5w6fw6q 2426 14 . . . cord-006870-f5w6fw6q 2427 1 In in IN cord-006870-f5w6fw6q 2427 2 septic septic JJ cord-006870-f5w6fw6q 2427 3 sheep sheep NNS cord-006870-f5w6fw6q 2427 4 infused infuse VBN cord-006870-f5w6fw6q 2427 5 with with IN cord-006870-f5w6fw6q 2427 6 Escherichia Escherichia NNP cord-006870-f5w6fw6q 2427 7 coli coli NNS cord-006870-f5w6fw6q 2427 8 , , , cord-006870-f5w6fw6q 2427 9 clonidine clonidine NN cord-006870-f5w6fw6q 2427 10 reduced reduce VBN cord-006870-f5w6fw6q 2427 11 renal renal JJ cord-006870-f5w6fw6q 2427 12 sympathetic sympathetic JJ cord-006870-f5w6fw6q 2427 13 tone tone NN cord-006870-f5w6fw6q 2427 14 and and CC cord-006870-f5w6fw6q 2427 15 restored restore VBD cord-006870-f5w6fw6q 2427 16 VR VR NNP cord-006870-f5w6fw6q 2427 17 . . . cord-006870-f5w6fw6q 2428 1 Additionally additionally RB cord-006870-f5w6fw6q 2428 2 , , , cord-006870-f5w6fw6q 2428 3 alpha-2 alpha-2 NN cord-006870-f5w6fw6q 2428 4 agonists agonist NNS cord-006870-f5w6fw6q 2428 5 have have VBP cord-006870-f5w6fw6q 2428 6 shown show VBN cord-006870-f5w6fw6q 2428 7 to to TO cord-006870-f5w6fw6q 2428 8 decrease decrease VB cord-006870-f5w6fw6q 2428 9 pro pro JJ cord-006870-f5w6fw6q 2428 10 - - JJ cord-006870-f5w6fw6q 2428 11 inflammatory inflammatory JJ cord-006870-f5w6fw6q 2428 12 cytokines cytokine NNS cord-006870-f5w6fw6q 2428 13 and and CC cord-006870-f5w6fw6q 2428 14 reduce reduce VB cord-006870-f5w6fw6q 2428 15 mortality mortality NN cord-006870-f5w6fw6q 2428 16 , , , cord-006870-f5w6fw6q 2428 17 improve improve VB cord-006870-f5w6fw6q 2428 18 capillary capillary JJ cord-006870-f5w6fw6q 2428 19 perfusion perfusion NN cord-006870-f5w6fw6q 2428 20 deficit deficit NN cord-006870-f5w6fw6q 2428 21 , , , cord-006870-f5w6fw6q 2428 22 and and CC cord-006870-f5w6fw6q 2428 23 lower low JJR cord-006870-f5w6fw6q 2428 24 arterial arterial JJ cord-006870-f5w6fw6q 2428 25 lactate lactate NN cord-006870-f5w6fw6q 2428 26 in in IN cord-006870-f5w6fw6q 2428 27 animal animal NN cord-006870-f5w6fw6q 2428 28 sepsis sepsis NN cord-006870-f5w6fw6q 2428 29 models model NNS cord-006870-f5w6fw6q 2428 30 . . . cord-006870-f5w6fw6q 2429 1 A a DT cord-006870-f5w6fw6q 2429 2 prospective prospective JJ cord-006870-f5w6fw6q 2429 3 trial trial NN cord-006870-f5w6fw6q 2429 4 in in IN cord-006870-f5w6fw6q 2429 5 human human JJ cord-006870-f5w6fw6q 2429 6 septic septic JJ cord-006870-f5w6fw6q 2429 7 shock shock NN cord-006870-f5w6fw6q 2429 8 is be VBZ cord-006870-f5w6fw6q 2429 9 in in IN cord-006870-f5w6fw6q 2429 10 the the DT cord-006870-f5w6fw6q 2429 11 pipeline pipeline NN cord-006870-f5w6fw6q 2429 12 . . . cord-006870-f5w6fw6q 2430 1 We -PRON- PRP cord-006870-f5w6fw6q 2430 2 report report VBP cord-006870-f5w6fw6q 2430 3 decreases decrease VBZ cord-006870-f5w6fw6q 2430 4 in in IN cord-006870-f5w6fw6q 2430 5 vasopressor vasopressor NN cord-006870-f5w6fw6q 2430 6 requirement requirement NN cord-006870-f5w6fw6q 2430 7 with with IN cord-006870-f5w6fw6q 2430 8 initiation initiation NN cord-006870-f5w6fw6q 2430 9 of of IN cord-006870-f5w6fw6q 2430 10 dexmedetomidine dexmedetomidine NN cord-006870-f5w6fw6q 2430 11 in in IN cord-006870-f5w6fw6q 2430 12 two two CD cord-006870-f5w6fw6q 2430 13 patients patient NNS cord-006870-f5w6fw6q 2430 14 with with IN cord-006870-f5w6fw6q 2430 15 brain brain NN cord-006870-f5w6fw6q 2430 16 injury injury NN cord-006870-f5w6fw6q 2430 17 . . . cord-006870-f5w6fw6q 2431 1 A a DT cord-006870-f5w6fw6q 2431 2 51-year 51-year JJ cord-006870-f5w6fw6q 2431 3 - - HYPH cord-006870-f5w6fw6q 2431 4 old old JJ cord-006870-f5w6fw6q 2431 5 woman woman NN cord-006870-f5w6fw6q 2431 6 presented present VBN cord-006870-f5w6fw6q 2431 7 with with IN cord-006870-f5w6fw6q 2431 8 a a DT cord-006870-f5w6fw6q 2431 9 high high JJ cord-006870-f5w6fw6q 2431 10 - - HYPH cord-006870-f5w6fw6q 2431 11 grade grade NN cord-006870-f5w6fw6q 2431 12 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2431 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2431 14 and and CC cord-006870-f5w6fw6q 2431 15 concomitant concomitant JJ cord-006870-f5w6fw6q 2431 16 reverse reverse NN cord-006870-f5w6fw6q 2431 17 Takatsubo Takatsubo NNP cord-006870-f5w6fw6q 2431 18 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 2431 19 . . . cord-006870-f5w6fw6q 2432 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 2432 2 clinical clinical JJ cord-006870-f5w6fw6q 2432 3 course course NN cord-006870-f5w6fw6q 2432 4 was be VBD cord-006870-f5w6fw6q 2432 5 complicated complicate VBN cord-006870-f5w6fw6q 2432 6 by by IN cord-006870-f5w6fw6q 2432 7 septic septic JJ cord-006870-f5w6fw6q 2432 8 shock shock NN cord-006870-f5w6fw6q 2432 9 secondary secondary JJ cord-006870-f5w6fw6q 2432 10 to to IN cord-006870-f5w6fw6q 2432 11 aspiration aspiration NN cord-006870-f5w6fw6q 2432 12 pneumonia pneumonia NN cord-006870-f5w6fw6q 2432 13 at at IN cord-006870-f5w6fw6q 2432 14 admission admission NN cord-006870-f5w6fw6q 2432 15 . . . cord-006870-f5w6fw6q 2433 1 When when WRB cord-006870-f5w6fw6q 2433 2 dexmedetomidine dexmedetomidine NNP cord-006870-f5w6fw6q 2433 3 was be VBD cord-006870-f5w6fw6q 2433 4 started start VBN cord-006870-f5w6fw6q 2433 5 after after IN cord-006870-f5w6fw6q 2433 6 36 36 CD cord-006870-f5w6fw6q 2433 7 hours hour NNS cord-006870-f5w6fw6q 2433 8 of of IN cord-006870-f5w6fw6q 2433 9 NE NE NNP cord-006870-f5w6fw6q 2433 10 infusion infusion NN cord-006870-f5w6fw6q 2433 11 , , , cord-006870-f5w6fw6q 2433 12 a a DT cord-006870-f5w6fw6q 2433 13 steady steady JJ cord-006870-f5w6fw6q 2433 14 decrease decrease NN cord-006870-f5w6fw6q 2433 15 in in IN cord-006870-f5w6fw6q 2433 16 NE NE NNP cord-006870-f5w6fw6q 2433 17 dosage dosage NN cord-006870-f5w6fw6q 2433 18 was be VBD cord-006870-f5w6fw6q 2433 19 observed observe VBN cord-006870-f5w6fw6q 2433 20 until until IN cord-006870-f5w6fw6q 2433 21 its -PRON- PRP$ cord-006870-f5w6fw6q 2433 22 discontinuation discontinuation NN cord-006870-f5w6fw6q 2433 23 . . . cord-006870-f5w6fw6q 2434 1 Increased increase VBN cord-006870-f5w6fw6q 2434 2 VR VR NNP cord-006870-f5w6fw6q 2434 3 was be VBD cord-006870-f5w6fw6q 2434 4 also also RB cord-006870-f5w6fw6q 2434 5 observed observe VBN cord-006870-f5w6fw6q 2434 6 in in IN cord-006870-f5w6fw6q 2434 7 a a DT cord-006870-f5w6fw6q 2434 8 33year 33year CD cord-006870-f5w6fw6q 2434 9 - - HYPH cord-006870-f5w6fw6q 2434 10 old old JJ cord-006870-f5w6fw6q 2434 11 man man NN cord-006870-f5w6fw6q 2434 12 being be VBG cord-006870-f5w6fw6q 2434 13 treated treat VBN cord-006870-f5w6fw6q 2434 14 for for IN cord-006870-f5w6fw6q 2434 15 new new JJ cord-006870-f5w6fw6q 2434 16 onset onset NN cord-006870-f5w6fw6q 2434 17 refractory refractory JJ cord-006870-f5w6fw6q 2434 18 status status NN cord-006870-f5w6fw6q 2434 19 epilepticus epilepticus NN cord-006870-f5w6fw6q 2434 20 . . . cord-006870-f5w6fw6q 2435 1 On on IN cord-006870-f5w6fw6q 2435 2 hospital hospital NN cord-006870-f5w6fw6q 2435 3 day day NN cord-006870-f5w6fw6q 2435 4 10 10 CD cord-006870-f5w6fw6q 2435 5 , , , cord-006870-f5w6fw6q 2435 6 the the DT cord-006870-f5w6fw6q 2435 7 patient patient NN cord-006870-f5w6fw6q 2435 8 continued continue VBD cord-006870-f5w6fw6q 2435 9 to to TO cord-006870-f5w6fw6q 2435 10 have have VB cord-006870-f5w6fw6q 2435 11 stimulus stimulus NN cord-006870-f5w6fw6q 2435 12 - - HYPH cord-006870-f5w6fw6q 2435 13 induced induce VBN cord-006870-f5w6fw6q 2435 14 seizures seizure NNS cord-006870-f5w6fw6q 2435 15 on on IN cord-006870-f5w6fw6q 2435 16 ketamine ketamine NN cord-006870-f5w6fw6q 2435 17 , , , cord-006870-f5w6fw6q 2435 18 midazolam midazolam NN cord-006870-f5w6fw6q 2435 19 and and CC cord-006870-f5w6fw6q 2435 20 pentobarbital pentobarbital JJ cord-006870-f5w6fw6q 2435 21 infusions infusion NNS cord-006870-f5w6fw6q 2435 22 and and CC cord-006870-f5w6fw6q 2435 23 required require VBD cord-006870-f5w6fw6q 2435 24 NE NE NNP cord-006870-f5w6fw6q 2435 25 to to TO cord-006870-f5w6fw6q 2435 26 maintain maintain VB cord-006870-f5w6fw6q 2435 27 an an DT cord-006870-f5w6fw6q 2435 28 adequate adequate JJ cord-006870-f5w6fw6q 2435 29 mean mean NN cord-006870-f5w6fw6q 2435 30 arterial arterial JJ cord-006870-f5w6fw6q 2435 31 pressure pressure NN cord-006870-f5w6fw6q 2435 32 . . . cord-006870-f5w6fw6q 2436 1 When when WRB cord-006870-f5w6fw6q 2436 2 dexmedetomidine dexmedetomidine NNP cord-006870-f5w6fw6q 2436 3 was be VBD cord-006870-f5w6fw6q 2436 4 added add VBN cord-006870-f5w6fw6q 2436 5 , , , cord-006870-f5w6fw6q 2436 6 a a DT cord-006870-f5w6fw6q 2436 7 decrease decrease NN cord-006870-f5w6fw6q 2436 8 in in IN cord-006870-f5w6fw6q 2436 9 NE NE NNP cord-006870-f5w6fw6q 2436 10 infusion infusion NN cord-006870-f5w6fw6q 2436 11 was be VBD cord-006870-f5w6fw6q 2436 12 observed observe VBN cord-006870-f5w6fw6q 2436 13 within within IN cord-006870-f5w6fw6q 2436 14 an an DT cord-006870-f5w6fw6q 2436 15 hour hour NN cord-006870-f5w6fw6q 2436 16 and and CC cord-006870-f5w6fw6q 2436 17 continued continue VBD cord-006870-f5w6fw6q 2436 18 for for IN cord-006870-f5w6fw6q 2436 19 six six CD cord-006870-f5w6fw6q 2436 20 hours hour NNS cord-006870-f5w6fw6q 2436 21 until until IN cord-006870-f5w6fw6q 2436 22 the the DT cord-006870-f5w6fw6q 2436 23 patient patient NN cord-006870-f5w6fw6q 2436 24 no no RB cord-006870-f5w6fw6q 2436 25 longer longer RB cord-006870-f5w6fw6q 2436 26 required require VBN cord-006870-f5w6fw6q 2436 27 vasopressor vasopressor NN cord-006870-f5w6fw6q 2436 28 therapy therapy NN cord-006870-f5w6fw6q 2436 29 . . . cord-006870-f5w6fw6q 2437 1 These these DT cord-006870-f5w6fw6q 2437 2 findings finding NNS cord-006870-f5w6fw6q 2437 3 are be VBP cord-006870-f5w6fw6q 2437 4 consistent consistent JJ cord-006870-f5w6fw6q 2437 5 with with IN cord-006870-f5w6fw6q 2437 6 aforementioned aforementioned JJ cord-006870-f5w6fw6q 2437 7 reports report NNS cord-006870-f5w6fw6q 2437 8 of of IN cord-006870-f5w6fw6q 2437 9 restored restore VBN cord-006870-f5w6fw6q 2437 10 VR VR NNP cord-006870-f5w6fw6q 2437 11 by by IN cord-006870-f5w6fw6q 2437 12 alpha-2 alpha-2 NN cord-006870-f5w6fw6q 2437 13 agonists agonist NNS cord-006870-f5w6fw6q 2437 14 in in IN cord-006870-f5w6fw6q 2437 15 septic septic JJ cord-006870-f5w6fw6q 2437 16 shock shock NN cord-006870-f5w6fw6q 2437 17 , , , cord-006870-f5w6fw6q 2437 18 and and CC cord-006870-f5w6fw6q 2437 19 warrant warrant VB cord-006870-f5w6fw6q 2437 20 further further JJ cord-006870-f5w6fw6q 2437 21 investigation investigation NN cord-006870-f5w6fw6q 2437 22 of of IN cord-006870-f5w6fw6q 2437 23 possible possible JJ cord-006870-f5w6fw6q 2437 24 beneficial beneficial JJ cord-006870-f5w6fw6q 2437 25 effects effect NNS cord-006870-f5w6fw6q 2437 26 of of IN cord-006870-f5w6fw6q 2437 27 attenuated attenuated JJ cord-006870-f5w6fw6q 2437 28 hyperadrenergic hyperadrenergic NN cord-006870-f5w6fw6q 2437 29 state state NN cord-006870-f5w6fw6q 2437 30 conferred confer VBN cord-006870-f5w6fw6q 2437 31 by by IN cord-006870-f5w6fw6q 2437 32 alpha-2 alpha-2 NN cord-006870-f5w6fw6q 2437 33 agonists agonist NNS cord-006870-f5w6fw6q 2437 34 in in IN cord-006870-f5w6fw6q 2437 35 various various JJ cord-006870-f5w6fw6q 2437 36 neurocritical neurocritical JJ cord-006870-f5w6fw6q 2437 37 care care NN cord-006870-f5w6fw6q 2437 38 settings setting NNS cord-006870-f5w6fw6q 2437 39 . . . cord-006870-f5w6fw6q 2438 1 Decreasing decrease VBG cord-006870-f5w6fw6q 2438 2 the the DT cord-006870-f5w6fw6q 2438 3 amount amount NN cord-006870-f5w6fw6q 2438 4 of of IN cord-006870-f5w6fw6q 2438 5 time time NN cord-006870-f5w6fw6q 2438 6 a a DT cord-006870-f5w6fw6q 2438 7 patient patient NN cord-006870-f5w6fw6q 2438 8 remains remain VBZ cord-006870-f5w6fw6q 2438 9 intubated intubate VBN cord-006870-f5w6fw6q 2438 10 has have VBZ cord-006870-f5w6fw6q 2438 11 been be VBN cord-006870-f5w6fw6q 2438 12 shown show VBN cord-006870-f5w6fw6q 2438 13 to to TO cord-006870-f5w6fw6q 2438 14 reduce reduce VB cord-006870-f5w6fw6q 2438 15 multiple multiple JJ cord-006870-f5w6fw6q 2438 16 negative negative JJ cord-006870-f5w6fw6q 2438 17 outcomes outcome NNS cord-006870-f5w6fw6q 2438 18 . . . cord-006870-f5w6fw6q 2439 1 By by IN cord-006870-f5w6fw6q 2439 2 extubating extubate VBG cord-006870-f5w6fw6q 2439 3 these these DT cord-006870-f5w6fw6q 2439 4 patients patient NNS cord-006870-f5w6fw6q 2439 5 earlier early RBR cord-006870-f5w6fw6q 2439 6 , , , cord-006870-f5w6fw6q 2439 7 risk risk NN cord-006870-f5w6fw6q 2439 8 of of IN cord-006870-f5w6fw6q 2439 9 infection infection NN cord-006870-f5w6fw6q 2439 10 , , , cord-006870-f5w6fw6q 2439 11 prolonged prolong VBN cord-006870-f5w6fw6q 2439 12 immobility immobility NN cord-006870-f5w6fw6q 2439 13 , , , cord-006870-f5w6fw6q 2439 14 and and CC cord-006870-f5w6fw6q 2439 15 delirium delirium NN cord-006870-f5w6fw6q 2439 16 are be VBP cord-006870-f5w6fw6q 2439 17 reduced reduce VBN cord-006870-f5w6fw6q 2439 18 . . . cord-006870-f5w6fw6q 2440 1 In in IN cord-006870-f5w6fw6q 2440 2 early early JJ cord-006870-f5w6fw6q 2440 3 2016 2016 CD cord-006870-f5w6fw6q 2440 4 , , , cord-006870-f5w6fw6q 2440 5 this this DT cord-006870-f5w6fw6q 2440 6 NSICU NSICU NNP cord-006870-f5w6fw6q 2440 7 was be VBD cord-006870-f5w6fw6q 2440 8 chosen choose VBN cord-006870-f5w6fw6q 2440 9 to to TO cord-006870-f5w6fw6q 2440 10 participate participate VB cord-006870-f5w6fw6q 2440 11 in in IN cord-006870-f5w6fw6q 2440 12 the the DT cord-006870-f5w6fw6q 2440 13 Society Society NNP cord-006870-f5w6fw6q 2440 14 of of IN cord-006870-f5w6fw6q 2440 15 Critical Critical NNP cord-006870-f5w6fw6q 2440 16 Care Care NNP cord-006870-f5w6fw6q 2440 17 Medicine Medicine NNP cord-006870-f5w6fw6q 2440 18 's 's POS cord-006870-f5w6fw6q 2440 19 ICU ICU NNP cord-006870-f5w6fw6q 2440 20 Liberation Liberation NNP cord-006870-f5w6fw6q 2440 21 Collaborative Collaborative NNP cord-006870-f5w6fw6q 2440 22 . . . cord-006870-f5w6fw6q 2441 1 The the DT cord-006870-f5w6fw6q 2441 2 collaborative collaborative NN cord-006870-f5w6fw6q 2441 3 was be VBD cord-006870-f5w6fw6q 2441 4 focused focus VBN cord-006870-f5w6fw6q 2441 5 on on IN cord-006870-f5w6fw6q 2441 6 implementation implementation NN cord-006870-f5w6fw6q 2441 7 of of IN cord-006870-f5w6fw6q 2441 8 the the DT cord-006870-f5w6fw6q 2441 9 ABCDEF ABCDEF NNP cord-006870-f5w6fw6q 2441 10 Bundle Bundle NNP cord-006870-f5w6fw6q 2441 11 or or CC cord-006870-f5w6fw6q 2441 12 ICU ICU NNP cord-006870-f5w6fw6q 2441 13 Liberation Liberation NNP cord-006870-f5w6fw6q 2441 14 . . . cord-006870-f5w6fw6q 2442 1 The the DT cord-006870-f5w6fw6q 2442 2 successful successful JJ cord-006870-f5w6fw6q 2442 3 implementation implementation NN cord-006870-f5w6fw6q 2442 4 of of IN cord-006870-f5w6fw6q 2442 5 the the DT cord-006870-f5w6fw6q 2442 6 bundle bundle NN cord-006870-f5w6fw6q 2442 7 led lead VBD cord-006870-f5w6fw6q 2442 8 to to IN cord-006870-f5w6fw6q 2442 9 a a DT cord-006870-f5w6fw6q 2442 10 decrease decrease NN cord-006870-f5w6fw6q 2442 11 in in IN cord-006870-f5w6fw6q 2442 12 the the DT cord-006870-f5w6fw6q 2442 13 amount amount NN cord-006870-f5w6fw6q 2442 14 of of IN cord-006870-f5w6fw6q 2442 15 time time NN cord-006870-f5w6fw6q 2442 16 neurocritically neurocritically RB cord-006870-f5w6fw6q 2442 17 ill ill JJ cord-006870-f5w6fw6q 2442 18 patients patient NNS cord-006870-f5w6fw6q 2442 19 were be VBD cord-006870-f5w6fw6q 2442 20 intubated intubate VBN cord-006870-f5w6fw6q 2442 21 . . . cord-006870-f5w6fw6q 2443 1 The the DT cord-006870-f5w6fw6q 2443 2 bundle bundle NN cord-006870-f5w6fw6q 2443 3 elements element NNS cord-006870-f5w6fw6q 2443 4 began begin VBD cord-006870-f5w6fw6q 2443 5 to to TO cord-006870-f5w6fw6q 2443 6 be be VB cord-006870-f5w6fw6q 2443 7 rolled roll VBN cord-006870-f5w6fw6q 2443 8 out out RP cord-006870-f5w6fw6q 2443 9 in in IN cord-006870-f5w6fw6q 2443 10 June June NNP cord-006870-f5w6fw6q 2443 11 2016 2016 CD cord-006870-f5w6fw6q 2443 12 ( ( -LRB- cord-006870-f5w6fw6q 2443 13 end end NN cord-006870-f5w6fw6q 2443 14 of of IN cord-006870-f5w6fw6q 2443 15 1st 1st JJ cord-006870-f5w6fw6q 2443 16 quarter quarter NN cord-006870-f5w6fw6q 2443 17 ) ) -RRB- cord-006870-f5w6fw6q 2443 18 . . . cord-006870-f5w6fw6q 2444 1 Included include VBN cord-006870-f5w6fw6q 2444 2 in in IN cord-006870-f5w6fw6q 2444 3 the the DT cord-006870-f5w6fw6q 2444 4 bundle bundle NN cord-006870-f5w6fw6q 2444 5 's 's POS cord-006870-f5w6fw6q 2444 6 roll roll NN cord-006870-f5w6fw6q 2444 7 out out RP cord-006870-f5w6fw6q 2444 8 was be VBD cord-006870-f5w6fw6q 2444 9 the the DT cord-006870-f5w6fw6q 2444 10 creation creation NN cord-006870-f5w6fw6q 2444 11 of of IN cord-006870-f5w6fw6q 2444 12 a a DT cord-006870-f5w6fw6q 2444 13 respiratory respiratory JJ cord-006870-f5w6fw6q 2444 14 clinical clinical JJ cord-006870-f5w6fw6q 2444 15 specialist specialist NN cord-006870-f5w6fw6q 2444 16 role role NN cord-006870-f5w6fw6q 2444 17 to to TO cord-006870-f5w6fw6q 2444 18 help help VB cord-006870-f5w6fw6q 2444 19 the the DT cord-006870-f5w6fw6q 2444 20 interprofessional interprofessional JJ cord-006870-f5w6fw6q 2444 21 team team NN cord-006870-f5w6fw6q 2444 22 with with IN cord-006870-f5w6fw6q 2444 23 the the DT cord-006870-f5w6fw6q 2444 24 respiratory respiratory JJ cord-006870-f5w6fw6q 2444 25 components component NNS cord-006870-f5w6fw6q 2444 26 of of IN cord-006870-f5w6fw6q 2444 27 the the DT cord-006870-f5w6fw6q 2444 28 bundle bundle NN cord-006870-f5w6fw6q 2444 29 . . . cord-006870-f5w6fw6q 2445 1 This this DT cord-006870-f5w6fw6q 2445 2 role role NN cord-006870-f5w6fw6q 2445 3 was be VBD cord-006870-f5w6fw6q 2445 4 a a DT cord-006870-f5w6fw6q 2445 5 full full JJ cord-006870-f5w6fw6q 2445 6 time time NN cord-006870-f5w6fw6q 2445 7 respiratory respiratory JJ cord-006870-f5w6fw6q 2445 8 care care NN cord-006870-f5w6fw6q 2445 9 practitioner practitioner NN cord-006870-f5w6fw6q 2445 10 who who WP cord-006870-f5w6fw6q 2445 11 was be VBD cord-006870-f5w6fw6q 2445 12 dedicated dedicate VBN cord-006870-f5w6fw6q 2445 13 to to IN cord-006870-f5w6fw6q 2445 14 the the DT cord-006870-f5w6fw6q 2445 15 NSICU NSICU NNP cord-006870-f5w6fw6q 2445 16 and and CC cord-006870-f5w6fw6q 2445 17 helped help VBD cord-006870-f5w6fw6q 2445 18 to to TO cord-006870-f5w6fw6q 2445 19 ensure ensure VB cord-006870-f5w6fw6q 2445 20 standards standard NNS cord-006870-f5w6fw6q 2445 21 were be VBD cord-006870-f5w6fw6q 2445 22 being be VBG cord-006870-f5w6fw6q 2445 23 met meet VBN cord-006870-f5w6fw6q 2445 24 . . . cord-006870-f5w6fw6q 2446 1 Additionally additionally RB cord-006870-f5w6fw6q 2446 2 , , , cord-006870-f5w6fw6q 2446 3 as as IN cord-006870-f5w6fw6q 2446 4 a a DT cord-006870-f5w6fw6q 2446 5 part part NN cord-006870-f5w6fw6q 2446 6 of of IN cord-006870-f5w6fw6q 2446 7 the the DT cord-006870-f5w6fw6q 2446 8 bundle bundle NN cord-006870-f5w6fw6q 2446 9 's 's POS cord-006870-f5w6fw6q 2446 10 implementation implementation NN cord-006870-f5w6fw6q 2446 11 , , , cord-006870-f5w6fw6q 2446 12 a a DT cord-006870-f5w6fw6q 2446 13 spontaneous spontaneous JJ cord-006870-f5w6fw6q 2446 14 awakening awakening NN cord-006870-f5w6fw6q 2446 15 trial trial NN cord-006870-f5w6fw6q 2446 16 and and CC cord-006870-f5w6fw6q 2446 17 spontaneous spontaneous JJ cord-006870-f5w6fw6q 2446 18 breathing breathing NN cord-006870-f5w6fw6q 2446 19 trial trial NN cord-006870-f5w6fw6q 2446 20 algorithm algorithm NN cord-006870-f5w6fw6q 2446 21 was be VBD cord-006870-f5w6fw6q 2446 22 developed develop VBN cord-006870-f5w6fw6q 2446 23 and and CC cord-006870-f5w6fw6q 2446 24 initiated initiate VBN cord-006870-f5w6fw6q 2446 25 . . . cord-006870-f5w6fw6q 2447 1 This this DT cord-006870-f5w6fw6q 2447 2 algorithm algorithm NN cord-006870-f5w6fw6q 2447 3 relied rely VBD cord-006870-f5w6fw6q 2447 4 on on IN cord-006870-f5w6fw6q 2447 5 interprofessional interprofessional JJ cord-006870-f5w6fw6q 2447 6 collaboration collaboration NN cord-006870-f5w6fw6q 2447 7 between between IN cord-006870-f5w6fw6q 2447 8 nursing nursing NN cord-006870-f5w6fw6q 2447 9 and and CC cord-006870-f5w6fw6q 2447 10 respiratory respiratory JJ cord-006870-f5w6fw6q 2447 11 therapy therapy NN cord-006870-f5w6fw6q 2447 12 with with IN cord-006870-f5w6fw6q 2447 13 communication communication NN cord-006870-f5w6fw6q 2447 14 to to IN cord-006870-f5w6fw6q 2447 15 the the DT cord-006870-f5w6fw6q 2447 16 provider provider NN cord-006870-f5w6fw6q 2447 17 and and CC cord-006870-f5w6fw6q 2447 18 was be VBD cord-006870-f5w6fw6q 2447 19 rolled roll VBN cord-006870-f5w6fw6q 2447 20 out out RP cord-006870-f5w6fw6q 2447 21 in in IN cord-006870-f5w6fw6q 2447 22 September September NNP cord-006870-f5w6fw6q 2447 23 2016 2016 CD cord-006870-f5w6fw6q 2447 24 ( ( -LRB- cord-006870-f5w6fw6q 2447 25 end end NN cord-006870-f5w6fw6q 2447 26 of of IN cord-006870-f5w6fw6q 2447 27 3rd 3rd JJ cord-006870-f5w6fw6q 2447 28 quarter quarter NN cord-006870-f5w6fw6q 2447 29 ) ) -RRB- cord-006870-f5w6fw6q 2447 30 . . . cord-006870-f5w6fw6q 2448 1 Ventilator Ventilator NNP cord-006870-f5w6fw6q 2448 2 O O NNP cord-006870-f5w6fw6q 2448 3 / / SYM cord-006870-f5w6fw6q 2448 4 E e NN cord-006870-f5w6fw6q 2448 5 for for IN cord-006870-f5w6fw6q 2448 6 2016 2016 CD cord-006870-f5w6fw6q 2448 7 : : : cord-006870-f5w6fw6q 2448 8 1st 1st NN cord-006870-f5w6fw6q 2448 9 quarter-0.953 quarter-0.953 NNS cord-006870-f5w6fw6q 2448 10 , , , cord-006870-f5w6fw6q 2448 11 2nd 2nd JJ cord-006870-f5w6fw6q 2448 12 quarter-0.989 quarter-0.989 NNP cord-006870-f5w6fw6q 2448 13 , , , cord-006870-f5w6fw6q 2448 14 3rd 3rd JJ cord-006870-f5w6fw6q 2448 15 quarter-0.827 quarter-0.827 NN cord-006870-f5w6fw6q 2448 16 , , , cord-006870-f5w6fw6q 2448 17 4th 4th JJ cord-006870-f5w6fw6q 2448 18 quarter-0.798 quarter-0.798 NN cord-006870-f5w6fw6q 2448 19 Ventilator Ventilator NNP cord-006870-f5w6fw6q 2448 20 O O NNP cord-006870-f5w6fw6q 2448 21 / / SYM cord-006870-f5w6fw6q 2448 22 E e NN cord-006870-f5w6fw6q 2448 23 for for IN cord-006870-f5w6fw6q 2448 24 2017 2017 CD cord-006870-f5w6fw6q 2448 25 : : : cord-006870-f5w6fw6q 2449 1 1st 1st NNP cord-006870-f5w6fw6q 2449 2 quarter-0.844 quarter-0.844 NNP cord-006870-f5w6fw6q 2449 3 , , , cord-006870-f5w6fw6q 2449 4 2nd 2nd JJ cord-006870-f5w6fw6q 2449 5 quarter-0.700 quarter-0.700 NN cord-006870-f5w6fw6q 2450 1 The the DT cord-006870-f5w6fw6q 2450 2 bulk bulk NN cord-006870-f5w6fw6q 2450 3 of of IN cord-006870-f5w6fw6q 2450 4 the the DT cord-006870-f5w6fw6q 2450 5 research research NN cord-006870-f5w6fw6q 2450 6 conducted conduct VBN cord-006870-f5w6fw6q 2450 7 that that WDT cord-006870-f5w6fw6q 2450 8 proved prove VBD cord-006870-f5w6fw6q 2450 9 the the DT cord-006870-f5w6fw6q 2450 10 benefits benefit NNS cord-006870-f5w6fw6q 2450 11 of of IN cord-006870-f5w6fw6q 2450 12 the the DT cord-006870-f5w6fw6q 2450 13 bundle bundle NN cord-006870-f5w6fw6q 2450 14 elements element NNS cord-006870-f5w6fw6q 2450 15 has have VBZ cord-006870-f5w6fw6q 2450 16 been be VBN cord-006870-f5w6fw6q 2450 17 completed complete VBN cord-006870-f5w6fw6q 2450 18 in in IN cord-006870-f5w6fw6q 2450 19 medical medical JJ cord-006870-f5w6fw6q 2450 20 and and CC cord-006870-f5w6fw6q 2450 21 / / SYM cord-006870-f5w6fw6q 2450 22 surgical surgical JJ cord-006870-f5w6fw6q 2450 23 patient patient NN cord-006870-f5w6fw6q 2450 24 populations population NNS cord-006870-f5w6fw6q 2450 25 . . . cord-006870-f5w6fw6q 2451 1 The the DT cord-006870-f5w6fw6q 2451 2 neurocritical neurocritical JJ cord-006870-f5w6fw6q 2451 3 care care NN cord-006870-f5w6fw6q 2451 4 patient patient NN cord-006870-f5w6fw6q 2451 5 population population NN cord-006870-f5w6fw6q 2451 6 is be VBZ cord-006870-f5w6fw6q 2451 7 very very RB cord-006870-f5w6fw6q 2451 8 specialized specialized JJ cord-006870-f5w6fw6q 2451 9 and and CC cord-006870-f5w6fw6q 2451 10 has have VBZ cord-006870-f5w6fw6q 2451 11 several several JJ cord-006870-f5w6fw6q 2451 12 nuances nuance NNS cord-006870-f5w6fw6q 2451 13 that that WDT cord-006870-f5w6fw6q 2451 14 may may MD cord-006870-f5w6fw6q 2451 15 impact impact VB cord-006870-f5w6fw6q 2451 16 the the DT cord-006870-f5w6fw6q 2451 17 way way NN cord-006870-f5w6fw6q 2451 18 the the DT cord-006870-f5w6fw6q 2451 19 various various JJ cord-006870-f5w6fw6q 2451 20 elements element NNS cord-006870-f5w6fw6q 2451 21 need need VBP cord-006870-f5w6fw6q 2451 22 to to TO cord-006870-f5w6fw6q 2451 23 be be VB cord-006870-f5w6fw6q 2451 24 implemented implement VBN cord-006870-f5w6fw6q 2451 25 . . . cord-006870-f5w6fw6q 2452 1 Through through IN cord-006870-f5w6fw6q 2452 2 this this DT cord-006870-f5w6fw6q 2452 3 process process NN cord-006870-f5w6fw6q 2452 4 , , , cord-006870-f5w6fw6q 2452 5 we -PRON- PRP cord-006870-f5w6fw6q 2452 6 have have VBP cord-006870-f5w6fw6q 2452 7 found find VBN cord-006870-f5w6fw6q 2452 8 that that IN cord-006870-f5w6fw6q 2452 9 the the DT cord-006870-f5w6fw6q 2452 10 techniques technique NNS cord-006870-f5w6fw6q 2452 11 suggested suggest VBN cord-006870-f5w6fw6q 2452 12 within within IN cord-006870-f5w6fw6q 2452 13 each each DT cord-006870-f5w6fw6q 2452 14 element element NN cord-006870-f5w6fw6q 2452 15 can can MD cord-006870-f5w6fw6q 2452 16 positively positively RB cord-006870-f5w6fw6q 2452 17 impact impact VB cord-006870-f5w6fw6q 2452 18 the the DT cord-006870-f5w6fw6q 2452 19 neurocritical neurocritical NNP cord-006870-f5w6fw6q 2452 20 care care NN cord-006870-f5w6fw6q 2452 21 patient patient NN cord-006870-f5w6fw6q 2452 22 population population NN cord-006870-f5w6fw6q 2452 23 . . . cord-006870-f5w6fw6q 2453 1 The the DT cord-006870-f5w6fw6q 2453 2 Cognitive Cognitive NNP cord-006870-f5w6fw6q 2453 3 Reserve Reserve NNP cord-006870-f5w6fw6q 2453 4 Hypothesis Hypothesis NNP cord-006870-f5w6fw6q 2453 5 refers refer VBZ cord-006870-f5w6fw6q 2453 6 to to IN cord-006870-f5w6fw6q 2453 7 inter inter JJ cord-006870-f5w6fw6q 2453 8 - - JJ cord-006870-f5w6fw6q 2453 9 individual individual JJ cord-006870-f5w6fw6q 2453 10 differences difference NNS cord-006870-f5w6fw6q 2453 11 in in IN cord-006870-f5w6fw6q 2453 12 the the DT cord-006870-f5w6fw6q 2453 13 ability ability NN cord-006870-f5w6fw6q 2453 14 of of IN cord-006870-f5w6fw6q 2453 15 patients patient NNS cord-006870-f5w6fw6q 2453 16 to to TO cord-006870-f5w6fw6q 2453 17 cope cope VB cord-006870-f5w6fw6q 2453 18 with with IN cord-006870-f5w6fw6q 2453 19 brain brain NN cord-006870-f5w6fw6q 2453 20 pathology pathology NN cord-006870-f5w6fw6q 2453 21 . . . cord-006870-f5w6fw6q 2454 1 Cognitive cognitive JJ cord-006870-f5w6fw6q 2454 2 reserve reserve NN cord-006870-f5w6fw6q 2454 3 can can MD cord-006870-f5w6fw6q 2454 4 be be VB cord-006870-f5w6fw6q 2454 5 measured measure VBN cord-006870-f5w6fw6q 2454 6 by by IN cord-006870-f5w6fw6q 2454 7 surrogate surrogate JJ cord-006870-f5w6fw6q 2454 8 markers marker NNS cord-006870-f5w6fw6q 2454 9 such such JJ cord-006870-f5w6fw6q 2454 10 as as IN cord-006870-f5w6fw6q 2454 11 education education NN cord-006870-f5w6fw6q 2454 12 and and CC cord-006870-f5w6fw6q 2454 13 occupation occupation NN cord-006870-f5w6fw6q 2454 14 and and CC cord-006870-f5w6fw6q 2454 15 has have VBZ cord-006870-f5w6fw6q 2454 16 shown show VBN cord-006870-f5w6fw6q 2454 17 to to TO cord-006870-f5w6fw6q 2454 18 be be VB cord-006870-f5w6fw6q 2454 19 an an DT cord-006870-f5w6fw6q 2454 20 important important JJ cord-006870-f5w6fw6q 2454 21 predictor predictor NN cord-006870-f5w6fw6q 2454 22 of of IN cord-006870-f5w6fw6q 2454 23 outcomes outcome NNS cord-006870-f5w6fw6q 2454 24 in in IN cord-006870-f5w6fw6q 2454 25 Alzheimer Alzheimer NNP cord-006870-f5w6fw6q 2454 26 disease disease NN cord-006870-f5w6fw6q 2454 27 , , , cord-006870-f5w6fw6q 2454 28 multiple multiple JJ cord-006870-f5w6fw6q 2454 29 sclerosis sclerosis NN cord-006870-f5w6fw6q 2454 30 and and CC cord-006870-f5w6fw6q 2454 31 traumatic traumatic JJ cord-006870-f5w6fw6q 2454 32 brain brain NN cord-006870-f5w6fw6q 2454 33 injury injury NN cord-006870-f5w6fw6q 2454 34 . . . cord-006870-f5w6fw6q 2455 1 In in IN cord-006870-f5w6fw6q 2455 2 this this DT cord-006870-f5w6fw6q 2455 3 prospective prospective JJ cord-006870-f5w6fw6q 2455 4 longitudinal longitudinal JJ cord-006870-f5w6fw6q 2455 5 cohort cohort NN cord-006870-f5w6fw6q 2455 6 study study NN cord-006870-f5w6fw6q 2455 7 we -PRON- PRP cord-006870-f5w6fw6q 2455 8 determined determine VBD cord-006870-f5w6fw6q 2455 9 whether whether IN cord-006870-f5w6fw6q 2455 10 cognitive cognitive JJ cord-006870-f5w6fw6q 2455 11 reserve reserve NN cord-006870-f5w6fw6q 2455 12 measured measure VBN cord-006870-f5w6fw6q 2455 13 as as IN cord-006870-f5w6fw6q 2455 14 number number NN cord-006870-f5w6fw6q 2455 15 of of IN cord-006870-f5w6fw6q 2455 16 years year NNS cord-006870-f5w6fw6q 2455 17 of of IN cord-006870-f5w6fw6q 2455 18 education education NN cord-006870-f5w6fw6q 2455 19 and and CC cord-006870-f5w6fw6q 2455 20 employment employment NN cord-006870-f5w6fw6q 2455 21 status status NN cord-006870-f5w6fw6q 2455 22 predicted predict VBD cord-006870-f5w6fw6q 2455 23 3-month 3-month CD cord-006870-f5w6fw6q 2455 24 functional functional JJ cord-006870-f5w6fw6q 2455 25 outcome outcome NN cord-006870-f5w6fw6q 2455 26 of of IN cord-006870-f5w6fw6q 2455 27 NCC NCC NNP cord-006870-f5w6fw6q 2455 28 patients patient NNS cord-006870-f5w6fw6q 2455 29 . . . cord-006870-f5w6fw6q 2456 1 Demographic demographic JJ cord-006870-f5w6fw6q 2456 2 and and CC cord-006870-f5w6fw6q 2456 3 clinical clinical JJ cord-006870-f5w6fw6q 2456 4 data datum NNS cord-006870-f5w6fw6q 2456 5 , , , cord-006870-f5w6fw6q 2456 6 including include VBG cord-006870-f5w6fw6q 2456 7 number number NN cord-006870-f5w6fw6q 2456 8 of of IN cord-006870-f5w6fw6q 2456 9 years year NNS cord-006870-f5w6fw6q 2456 10 of of IN cord-006870-f5w6fw6q 2456 11 education education NN cord-006870-f5w6fw6q 2456 12 and and CC cord-006870-f5w6fw6q 2456 13 occupational occupational JJ cord-006870-f5w6fw6q 2456 14 status status NN cord-006870-f5w6fw6q 2456 15 , , , cord-006870-f5w6fw6q 2456 16 were be VBD cord-006870-f5w6fw6q 2456 17 collected collect VBN cord-006870-f5w6fw6q 2456 18 . . . cord-006870-f5w6fw6q 2457 1 At at IN cord-006870-f5w6fw6q 2457 2 three three CD cord-006870-f5w6fw6q 2457 3 months month NNS cord-006870-f5w6fw6q 2457 4 after after IN cord-006870-f5w6fw6q 2457 5 discharge discharge NN cord-006870-f5w6fw6q 2457 6 , , , cord-006870-f5w6fw6q 2457 7 Glasgow Glasgow NNP cord-006870-f5w6fw6q 2457 8 Outcome outcome NN cord-006870-f5w6fw6q 2457 9 Scales Scales NNP cord-006870-f5w6fw6q 2457 10 ( ( -LRB- cord-006870-f5w6fw6q 2457 11 GOS GOS NNP cord-006870-f5w6fw6q 2457 12 ) ) -RRB- cord-006870-f5w6fw6q 2457 13 were be VBD cord-006870-f5w6fw6q 2457 14 collected collect VBN cord-006870-f5w6fw6q 2457 15 via via IN cord-006870-f5w6fw6q 2457 16 telephone telephone NN cord-006870-f5w6fw6q 2457 17 from from IN cord-006870-f5w6fw6q 2457 18 patients patient NNS cord-006870-f5w6fw6q 2457 19 or or CC cord-006870-f5w6fw6q 2457 20 surrogate surrogate JJ cord-006870-f5w6fw6q 2457 21 respondents respondent NNS cord-006870-f5w6fw6q 2457 22 . . . cord-006870-f5w6fw6q 2458 1 GOS GOS NNP cord-006870-f5w6fw6q 2458 2 scores score NNS cord-006870-f5w6fw6q 2458 3 were be VBD cord-006870-f5w6fw6q 2458 4 categorized categorize VBN cord-006870-f5w6fw6q 2458 5 into into IN cord-006870-f5w6fw6q 2458 6 ' ' `` cord-006870-f5w6fw6q 2458 7 Good Good NNP cord-006870-f5w6fw6q 2458 8 ' ' '' cord-006870-f5w6fw6q 2458 9 or or CC cord-006870-f5w6fw6q 2458 10 ' ' `` cord-006870-f5w6fw6q 2458 11 Poor poor JJ cord-006870-f5w6fw6q 2458 12 ' ' POS cord-006870-f5w6fw6q 2458 13 outcome outcome NN cord-006870-f5w6fw6q 2458 14 ( ( -LRB- cord-006870-f5w6fw6q 2458 15 GOS GOS NNP cord-006870-f5w6fw6q 2458 16 1 1 CD cord-006870-f5w6fw6q 2458 17 - - SYM cord-006870-f5w6fw6q 2458 18 3 3 CD cord-006870-f5w6fw6q 2458 19 ) ) -RRB- cord-006870-f5w6fw6q 2458 20 . . . cord-006870-f5w6fw6q 2459 1 From from IN cord-006870-f5w6fw6q 2459 2 March March NNP cord-006870-f5w6fw6q 2459 3 2016 2016 CD cord-006870-f5w6fw6q 2459 4 to to IN cord-006870-f5w6fw6q 2459 5 July July NNP cord-006870-f5w6fw6q 2459 6 2016 2016 CD cord-006870-f5w6fw6q 2459 7 , , , cord-006870-f5w6fw6q 2459 8 35/83 35/83 CD cord-006870-f5w6fw6q 2459 9 patients patient NNS cord-006870-f5w6fw6q 2459 10 with with IN cord-006870-f5w6fw6q 2459 11 3-month 3-month CD cord-006870-f5w6fw6q 2459 12 follow follow VB cord-006870-f5w6fw6q 2459 13 - - HYPH cord-006870-f5w6fw6q 2459 14 up up NN cord-006870-f5w6fw6q 2459 15 data datum NNS cord-006870-f5w6fw6q 2459 16 were be VBD cord-006870-f5w6fw6q 2459 17 included include VBN cord-006870-f5w6fw6q 2459 18 . . . cord-006870-f5w6fw6q 2460 1 Mean mean JJ cord-006870-f5w6fw6q 2460 2 age age NN cord-006870-f5w6fw6q 2460 3 was be VBD cord-006870-f5w6fw6q 2460 4 56 56 CD cord-006870-f5w6fw6q 2460 5 ± ± CD cord-006870-f5w6fw6q 2460 6 19 19 CD cord-006870-f5w6fw6q 2460 7 years year NNS cord-006870-f5w6fw6q 2460 8 , , , cord-006870-f5w6fw6q 2460 9 12 12 CD cord-006870-f5w6fw6q 2460 10 ( ( -LRB- cord-006870-f5w6fw6q 2460 11 34 34 CD cord-006870-f5w6fw6q 2460 12 % % NN cord-006870-f5w6fw6q 2460 13 ) ) -RRB- cord-006870-f5w6fw6q 2460 14 were be VBD cord-006870-f5w6fw6q 2460 15 male male JJ cord-006870-f5w6fw6q 2460 16 , , , cord-006870-f5w6fw6q 2460 17 with with IN cord-006870-f5w6fw6q 2460 18 stroke stroke NN cord-006870-f5w6fw6q 2460 19 as as IN cord-006870-f5w6fw6q 2460 20 the the DT cord-006870-f5w6fw6q 2460 21 predominant predominant JJ cord-006870-f5w6fw6q 2460 22 admitting admit VBG cord-006870-f5w6fw6q 2460 23 diagnosis diagnosis NN cord-006870-f5w6fw6q 2460 24 . . . cord-006870-f5w6fw6q 2461 1 The the DT cord-006870-f5w6fw6q 2461 2 two two CD cord-006870-f5w6fw6q 2461 3 groups group NNS cord-006870-f5w6fw6q 2461 4 with with IN cord-006870-f5w6fw6q 2461 5 good good JJ cord-006870-f5w6fw6q 2461 6 vs vs IN cord-006870-f5w6fw6q 2461 7 poor poor JJ cord-006870-f5w6fw6q 2461 8 outcomes outcome NNS cord-006870-f5w6fw6q 2461 9 did do VBD cord-006870-f5w6fw6q 2461 10 not not RB cord-006870-f5w6fw6q 2461 11 differ differ VB cord-006870-f5w6fw6q 2461 12 in in IN cord-006870-f5w6fw6q 2461 13 age age NN cord-006870-f5w6fw6q 2461 14 , , , cord-006870-f5w6fw6q 2461 15 gender gender NN cord-006870-f5w6fw6q 2461 16 or or CC cord-006870-f5w6fw6q 2461 17 race race NN cord-006870-f5w6fw6q 2461 18 in in IN cord-006870-f5w6fw6q 2461 19 univariate univariate JJ cord-006870-f5w6fw6q 2461 20 analysis analysis NN cord-006870-f5w6fw6q 2461 21 although although IN cord-006870-f5w6fw6q 2461 22 employment employment NN cord-006870-f5w6fw6q 2461 23 status status NN cord-006870-f5w6fw6q 2461 24 was be VBD cord-006870-f5w6fw6q 2461 25 statistically statistically RB cord-006870-f5w6fw6q 2461 26 different different JJ cord-006870-f5w6fw6q 2461 27 in in IN cord-006870-f5w6fw6q 2461 28 the the DT cord-006870-f5w6fw6q 2461 29 two two CD cord-006870-f5w6fw6q 2461 30 groups group NNS cord-006870-f5w6fw6q 2461 31 . . . cord-006870-f5w6fw6q 2462 1 In in IN cord-006870-f5w6fw6q 2462 2 multivariate multivariate JJ cord-006870-f5w6fw6q 2462 3 logistic logistic JJ cord-006870-f5w6fw6q 2462 4 regression regression NN cord-006870-f5w6fw6q 2462 5 neither neither CC cord-006870-f5w6fw6q 2462 6 employment employment NN cord-006870-f5w6fw6q 2462 7 nor nor CC cord-006870-f5w6fw6q 2462 8 education education NN cord-006870-f5w6fw6q 2462 9 was be VBD cord-006870-f5w6fw6q 2462 10 a a DT cord-006870-f5w6fw6q 2462 11 significant significant JJ cord-006870-f5w6fw6q 2462 12 predictor predictor NN cord-006870-f5w6fw6q 2462 13 of of IN cord-006870-f5w6fw6q 2462 14 good good NN cord-006870-f5w6fw6q 2462 15 vs vs IN cord-006870-f5w6fw6q 2462 16 poor poor JJ cord-006870-f5w6fw6q 2462 17 outcome outcome NN cord-006870-f5w6fw6q 2463 1 ( ( -LRB- cord-006870-f5w6fw6q 2463 2 P p NN cord-006870-f5w6fw6q 2463 3 = = SYM cord-006870-f5w6fw6q 2463 4 0.34 0.34 CD cord-006870-f5w6fw6q 2463 5 , , , cord-006870-f5w6fw6q 2463 6 P p NN cord-006870-f5w6fw6q 2463 7 = = SYM cord-006870-f5w6fw6q 2463 8 0.88 0.88 CD cord-006870-f5w6fw6q 2463 9 ) ) -RRB- cord-006870-f5w6fw6q 2463 10 . . . cord-006870-f5w6fw6q 2464 1 Prognostication prognostication NN cord-006870-f5w6fw6q 2464 2 in in IN cord-006870-f5w6fw6q 2464 3 neurocritical neurocritical JJ cord-006870-f5w6fw6q 2464 4 care care NN cord-006870-f5w6fw6q 2464 5 patients patient NNS cord-006870-f5w6fw6q 2464 6 is be VBZ cord-006870-f5w6fw6q 2464 7 difficult difficult JJ cord-006870-f5w6fw6q 2464 8 . . . cord-006870-f5w6fw6q 2465 1 The the DT cord-006870-f5w6fw6q 2465 2 effect effect NN cord-006870-f5w6fw6q 2465 3 of of IN cord-006870-f5w6fw6q 2465 4 cognitive cognitive JJ cord-006870-f5w6fw6q 2465 5 reserve reserve NN cord-006870-f5w6fw6q 2465 6 needs need NNS cord-006870-f5w6fw6q 2465 7 to to TO cord-006870-f5w6fw6q 2465 8 be be VB cord-006870-f5w6fw6q 2465 9 studied study VBN cord-006870-f5w6fw6q 2465 10 further further RB cord-006870-f5w6fw6q 2465 11 . . . cord-006870-f5w6fw6q 2466 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2466 2 current current JJ cord-006870-f5w6fw6q 2466 3 sample sample NN cord-006870-f5w6fw6q 2466 4 size size NN cord-006870-f5w6fw6q 2466 5 is be VBZ cord-006870-f5w6fw6q 2466 6 small small JJ cord-006870-f5w6fw6q 2466 7 and and CC cord-006870-f5w6fw6q 2466 8 as as IN cord-006870-f5w6fw6q 2466 9 enrollment enrollment NN cord-006870-f5w6fw6q 2466 10 continues continue VBZ cord-006870-f5w6fw6q 2466 11 , , , cord-006870-f5w6fw6q 2466 12 we -PRON- PRP cord-006870-f5w6fw6q 2466 13 will will MD cord-006870-f5w6fw6q 2466 14 determine determine VB cord-006870-f5w6fw6q 2466 15 the the DT cord-006870-f5w6fw6q 2466 16 relationship relationship NN cord-006870-f5w6fw6q 2466 17 between between IN cord-006870-f5w6fw6q 2466 18 cognitive cognitive NNP cord-006870-f5w6fw6q 2466 19 reserve reserve NN cord-006870-f5w6fw6q 2466 20 and and CC cord-006870-f5w6fw6q 2466 21 3-month 3-month CD cord-006870-f5w6fw6q 2466 22 functional functional JJ cord-006870-f5w6fw6q 2466 23 outcome outcome NN cord-006870-f5w6fw6q 2466 24 . . . cord-006870-f5w6fw6q 2467 1 Fever fever NN cord-006870-f5w6fw6q 2467 2 commonly commonly RB cord-006870-f5w6fw6q 2467 3 occurs occur VBZ cord-006870-f5w6fw6q 2467 4 in in IN cord-006870-f5w6fw6q 2467 5 patients patient NNS cord-006870-f5w6fw6q 2467 6 with with IN cord-006870-f5w6fw6q 2467 7 spontaneous spontaneous JJ cord-006870-f5w6fw6q 2467 8 intracerebral intracerebral JJ cord-006870-f5w6fw6q 2467 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2467 10 ( ( -LRB- cord-006870-f5w6fw6q 2467 11 sICH sich NN cord-006870-f5w6fw6q 2467 12 ) ) -RRB- cord-006870-f5w6fw6q 2467 13 . . . cord-006870-f5w6fw6q 2468 1 However however RB cord-006870-f5w6fw6q 2468 2 , , , cord-006870-f5w6fw6q 2468 3 it -PRON- PRP cord-006870-f5w6fw6q 2468 4 is be VBZ cord-006870-f5w6fw6q 2468 5 non non JJ cord-006870-f5w6fw6q 2468 6 - - JJ cord-006870-f5w6fw6q 2468 7 infectious infectious JJ cord-006870-f5w6fw6q 2468 8 in in IN cord-006870-f5w6fw6q 2468 9 the the DT cord-006870-f5w6fw6q 2468 10 majority majority NN cord-006870-f5w6fw6q 2468 11 of of IN cord-006870-f5w6fw6q 2468 12 cases case NNS cord-006870-f5w6fw6q 2468 13 . . . cord-006870-f5w6fw6q 2469 1 Blood blood NN cord-006870-f5w6fw6q 2469 2 cultures culture NNS cord-006870-f5w6fw6q 2469 3 ( ( -LRB- cord-006870-f5w6fw6q 2469 4 BCx BCx NNP cord-006870-f5w6fw6q 2469 5 ) ) -RRB- cord-006870-f5w6fw6q 2469 6 are be VBP cord-006870-f5w6fw6q 2469 7 often often RB cord-006870-f5w6fw6q 2469 8 obtained obtain VBN cord-006870-f5w6fw6q 2469 9 as as IN cord-006870-f5w6fw6q 2469 10 part part NN cord-006870-f5w6fw6q 2469 11 of of IN cord-006870-f5w6fw6q 2469 12 a a DT cord-006870-f5w6fw6q 2469 13 fever fever NN cord-006870-f5w6fw6q 2469 14 workup workup NN cord-006870-f5w6fw6q 2469 15 , , , cord-006870-f5w6fw6q 2469 16 yet yet CC cord-006870-f5w6fw6q 2469 17 their -PRON- PRP$ cord-006870-f5w6fw6q 2469 18 utility utility NN cord-006870-f5w6fw6q 2469 19 may may MD cord-006870-f5w6fw6q 2469 20 be be VB cord-006870-f5w6fw6q 2469 21 limited limited JJ cord-006870-f5w6fw6q 2469 22 and and CC cord-006870-f5w6fw6q 2469 23 false false JJ cord-006870-f5w6fw6q 2469 24 - - HYPH cord-006870-f5w6fw6q 2469 25 positive positive JJ cord-006870-f5w6fw6q 2469 26 results result NNS cord-006870-f5w6fw6q 2469 27 may may MD cord-006870-f5w6fw6q 2469 28 potentially potentially RB cord-006870-f5w6fw6q 2469 29 compromise compromise VB cord-006870-f5w6fw6q 2469 30 patient patient NN cord-006870-f5w6fw6q 2469 31 care care NN cord-006870-f5w6fw6q 2469 32 . . . cord-006870-f5w6fw6q 2470 1 We -PRON- PRP cord-006870-f5w6fw6q 2470 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 2470 3 blood blood NN cord-006870-f5w6fw6q 2470 4 cultures culture NNS cord-006870-f5w6fw6q 2470 5 in in IN cord-006870-f5w6fw6q 2470 6 the the DT cord-006870-f5w6fw6q 2470 7 first first JJ cord-006870-f5w6fw6q 2470 8 48 48 CD cord-006870-f5w6fw6q 2470 9 hours hour NNS cord-006870-f5w6fw6q 2470 10 would would MD cord-006870-f5w6fw6q 2470 11 more more RBR cord-006870-f5w6fw6q 2470 12 likely likely RB cord-006870-f5w6fw6q 2470 13 be be VB cord-006870-f5w6fw6q 2470 14 false false JJ cord-006870-f5w6fw6q 2470 15 - - HYPH cord-006870-f5w6fw6q 2470 16 positive positive JJ cord-006870-f5w6fw6q 2470 17 . . . cord-006870-f5w6fw6q 2471 1 We -PRON- PRP cord-006870-f5w6fw6q 2471 2 performed perform VBD cord-006870-f5w6fw6q 2471 3 a a DT cord-006870-f5w6fw6q 2471 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2471 5 chart chart NN cord-006870-f5w6fw6q 2471 6 review review NN cord-006870-f5w6fw6q 2471 7 of of IN cord-006870-f5w6fw6q 2471 8 patients patient NNS cord-006870-f5w6fw6q 2471 9 admitted admit VBN cord-006870-f5w6fw6q 2471 10 to to IN cord-006870-f5w6fw6q 2471 11 a a DT cord-006870-f5w6fw6q 2471 12 tertiary tertiary JJ cord-006870-f5w6fw6q 2471 13 medical medical JJ cord-006870-f5w6fw6q 2471 14 center center NN cord-006870-f5w6fw6q 2471 15 with with IN cord-006870-f5w6fw6q 2471 16 a a DT cord-006870-f5w6fw6q 2471 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 2471 18 of of IN cord-006870-f5w6fw6q 2471 19 spontaneous spontaneous JJ cord-006870-f5w6fw6q 2471 20 intracerebral intracerebral JJ cord-006870-f5w6fw6q 2471 21 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2471 22 . . . cord-006870-f5w6fw6q 2472 1 Patients patient NNS cord-006870-f5w6fw6q 2472 2 with with IN cord-006870-f5w6fw6q 2472 3 secondary secondary JJ cord-006870-f5w6fw6q 2472 4 causes cause NNS cord-006870-f5w6fw6q 2472 5 of of IN cord-006870-f5w6fw6q 2472 6 ICH ICH NNP cord-006870-f5w6fw6q 2472 7 as as RB cord-006870-f5w6fw6q 2472 8 well well RB cord-006870-f5w6fw6q 2472 9 as as IN cord-006870-f5w6fw6q 2472 10 institution institution NN cord-006870-f5w6fw6q 2472 11 of of IN cord-006870-f5w6fw6q 2472 12 comfort comfort NN cord-006870-f5w6fw6q 2472 13 measures measure NNS cord-006870-f5w6fw6q 2472 14 only only RB cord-006870-f5w6fw6q 2472 15 were be VBD cord-006870-f5w6fw6q 2472 16 excluded exclude VBN cord-006870-f5w6fw6q 2472 17 . . . cord-006870-f5w6fw6q 2473 1 Data datum NNS cord-006870-f5w6fw6q 2473 2 obtained obtain VBD cord-006870-f5w6fw6q 2473 3 included include VBN cord-006870-f5w6fw6q 2473 4 demographics demographic NNS cord-006870-f5w6fw6q 2473 5 , , , cord-006870-f5w6fw6q 2473 6 clinical clinical JJ cord-006870-f5w6fw6q 2473 7 parameters parameter NNS cord-006870-f5w6fw6q 2473 8 of of IN cord-006870-f5w6fw6q 2473 9 ICH ICH NNP cord-006870-f5w6fw6q 2473 10 and and CC cord-006870-f5w6fw6q 2473 11 blood blood NN cord-006870-f5w6fw6q 2473 12 culture culture NN cord-006870-f5w6fw6q 2473 13 results result NNS cord-006870-f5w6fw6q 2473 14 . . . cord-006870-f5w6fw6q 2474 1 Blood blood NN cord-006870-f5w6fw6q 2474 2 culture culture NN cord-006870-f5w6fw6q 2474 3 results result NNS cord-006870-f5w6fw6q 2474 4 and and CC cord-006870-f5w6fw6q 2474 5 charts chart NNS cord-006870-f5w6fw6q 2474 6 were be VBD cord-006870-f5w6fw6q 2474 7 reviewed review VBN cord-006870-f5w6fw6q 2474 8 for for IN cord-006870-f5w6fw6q 2474 9 adjudication adjudication NN cord-006870-f5w6fw6q 2474 10 of of IN cord-006870-f5w6fw6q 2474 11 false false JJ cord-006870-f5w6fw6q 2474 12 - - HYPH cord-006870-f5w6fw6q 2474 13 positive positive JJ cord-006870-f5w6fw6q 2474 14 and and CC cord-006870-f5w6fw6q 2474 15 true true JJ cord-006870-f5w6fw6q 2474 16 - - HYPH cord-006870-f5w6fw6q 2474 17 positive positive JJ cord-006870-f5w6fw6q 2474 18 cultures culture NNS cord-006870-f5w6fw6q 2474 19 . . . cord-006870-f5w6fw6q 2475 1 Of of IN cord-006870-f5w6fw6q 2475 2 654 654 CD cord-006870-f5w6fw6q 2475 3 included include VBD cord-006870-f5w6fw6q 2475 4 patients patient NNS cord-006870-f5w6fw6q 2475 5 with with IN cord-006870-f5w6fw6q 2475 6 sICH sich NN cord-006870-f5w6fw6q 2475 7 , , , cord-006870-f5w6fw6q 2475 8 226 226 CD cord-006870-f5w6fw6q 2475 9 patients patient NNS cord-006870-f5w6fw6q 2475 10 ( ( -LRB- cord-006870-f5w6fw6q 2475 11 34 34 CD cord-006870-f5w6fw6q 2475 12 % % NN cord-006870-f5w6fw6q 2475 13 ) ) -RRB- cord-006870-f5w6fw6q 2475 14 had have VBD cord-006870-f5w6fw6q 2475 15 1065 1065 CD cord-006870-f5w6fw6q 2475 16 blood blood NN cord-006870-f5w6fw6q 2475 17 cultures culture NNS cord-006870-f5w6fw6q 2475 18 obtained obtain VBN cord-006870-f5w6fw6q 2475 19 . . . cord-006870-f5w6fw6q 2476 1 52 52 CD cord-006870-f5w6fw6q 2476 2 cultures culture NNS cord-006870-f5w6fw6q 2476 3 were be VBD cord-006870-f5w6fw6q 2476 4 positive positive JJ cord-006870-f5w6fw6q 2476 5 , , , cord-006870-f5w6fw6q 2476 6 of of IN cord-006870-f5w6fw6q 2476 7 which which WDT cord-006870-f5w6fw6q 2476 8 23 23 CD cord-006870-f5w6fw6q 2476 9 were be VBD cord-006870-f5w6fw6q 2476 10 classified classify VBN cord-006870-f5w6fw6q 2476 11 as as IN cord-006870-f5w6fw6q 2476 12 false false JJ cord-006870-f5w6fw6q 2476 13 - - HYPH cord-006870-f5w6fw6q 2476 14 positive positive JJ cord-006870-f5w6fw6q 2476 15 and and CC cord-006870-f5w6fw6q 2476 16 29 29 CD cord-006870-f5w6fw6q 2476 17 as as RB cord-006870-f5w6fw6q 2476 18 true true JJ cord-006870-f5w6fw6q 2476 19 positive positive JJ cord-006870-f5w6fw6q 2476 20 . . . cord-006870-f5w6fw6q 2477 1 False false JJ cord-006870-f5w6fw6q 2477 2 positive positive JJ cord-006870-f5w6fw6q 2477 3 results result NNS cord-006870-f5w6fw6q 2477 4 were be VBD cord-006870-f5w6fw6q 2477 5 more more RBR cord-006870-f5w6fw6q 2477 6 common common JJ cord-006870-f5w6fw6q 2477 7 in in IN cord-006870-f5w6fw6q 2477 8 the the DT cord-006870-f5w6fw6q 2477 9 first first JJ cord-006870-f5w6fw6q 2477 10 2 2 CD cord-006870-f5w6fw6q 2477 11 days day NNS cord-006870-f5w6fw6q 2477 12 ( ( -LRB- cord-006870-f5w6fw6q 2477 13 17 17 CD cord-006870-f5w6fw6q 2477 14 vs. vs. NN cord-006870-f5w6fw6q 2477 15 6 6 CD cord-006870-f5w6fw6q 2477 16 ) ) -RRB- cord-006870-f5w6fw6q 2477 17 , , , cord-006870-f5w6fw6q 2477 18 while while IN cord-006870-f5w6fw6q 2477 19 true true JJ cord-006870-f5w6fw6q 2477 20 positive positive JJ cord-006870-f5w6fw6q 2477 21 results result NNS cord-006870-f5w6fw6q 2477 22 were be VBD cord-006870-f5w6fw6q 2477 23 more more RBR cord-006870-f5w6fw6q 2477 24 common common JJ cord-006870-f5w6fw6q 2477 25 after after IN cord-006870-f5w6fw6q 2477 26 the the DT cord-006870-f5w6fw6q 2477 27 first first JJ cord-006870-f5w6fw6q 2477 28 48 48 CD cord-006870-f5w6fw6q 2477 29 hours hour NNS cord-006870-f5w6fw6q 2477 30 ( ( -LRB- cord-006870-f5w6fw6q 2477 31 12 12 CD cord-006870-f5w6fw6q 2477 32 vs. vs. NN cord-006870-f5w6fw6q 2477 33 17 17 CD cord-006870-f5w6fw6q 2477 34 ) ) -RRB- cord-006870-f5w6fw6q 2477 35 ( ( -LRB- cord-006870-f5w6fw6q 2477 36 p= p= NNP cord-006870-f5w6fw6q 2477 37 0.018 0.018 CD cord-006870-f5w6fw6q 2477 38 ) ) -RRB- cord-006870-f5w6fw6q 2477 39 . . . cord-006870-f5w6fw6q 2478 1 Early early JJ cord-006870-f5w6fw6q 2478 2 blood blood NN cord-006870-f5w6fw6q 2478 3 cultures culture NNS cord-006870-f5w6fw6q 2478 4 in in IN cord-006870-f5w6fw6q 2478 5 patients patient NNS cord-006870-f5w6fw6q 2478 6 with with IN cord-006870-f5w6fw6q 2478 7 sICH sich NN cord-006870-f5w6fw6q 2478 8 are be VBP cord-006870-f5w6fw6q 2478 9 more more RBR cord-006870-f5w6fw6q 2478 10 commonly commonly RB cord-006870-f5w6fw6q 2478 11 non non JJ cord-006870-f5w6fw6q 2478 12 - - JJ cord-006870-f5w6fw6q 2478 13 infectious infectious JJ cord-006870-f5w6fw6q 2478 14 . . . cord-006870-f5w6fw6q 2479 1 In in IN cord-006870-f5w6fw6q 2479 2 line line NN cord-006870-f5w6fw6q 2479 3 with with IN cord-006870-f5w6fw6q 2479 4 prior prior JJ cord-006870-f5w6fw6q 2479 5 published publish VBN cord-006870-f5w6fw6q 2479 6 data datum NNS cord-006870-f5w6fw6q 2479 7 , , , cord-006870-f5w6fw6q 2479 8 our -PRON- PRP$ cord-006870-f5w6fw6q 2479 9 results result NNS cord-006870-f5w6fw6q 2479 10 demonstrate demonstrate VBP cord-006870-f5w6fw6q 2479 11 the the DT cord-006870-f5w6fw6q 2479 12 high high JJ cord-006870-f5w6fw6q 2479 13 cost cost NN cord-006870-f5w6fw6q 2479 14 and and CC cord-006870-f5w6fw6q 2479 15 limited limited JJ cord-006870-f5w6fw6q 2479 16 yield yield NN cord-006870-f5w6fw6q 2479 17 for for IN cord-006870-f5w6fw6q 2479 18 blood blood NN cord-006870-f5w6fw6q 2479 19 cultures culture NNS cord-006870-f5w6fw6q 2479 20 within within IN cord-006870-f5w6fw6q 2479 21 the the DT cord-006870-f5w6fw6q 2479 22 first first JJ cord-006870-f5w6fw6q 2479 23 48 48 CD cord-006870-f5w6fw6q 2479 24 hours hour NNS cord-006870-f5w6fw6q 2479 25 . . . cord-006870-f5w6fw6q 2480 1 Predictive predictive JJ cord-006870-f5w6fw6q 2480 2 energy energy NN cord-006870-f5w6fw6q 2480 3 expenditure expenditure NN cord-006870-f5w6fw6q 2480 4 ( ( -LRB- cord-006870-f5w6fw6q 2480 5 PEE PEE NNP cord-006870-f5w6fw6q 2480 6 ) ) -RRB- cord-006870-f5w6fw6q 2480 7 equations equation NNS cord-006870-f5w6fw6q 2480 8 are be VBP cord-006870-f5w6fw6q 2480 9 commonly commonly RB cord-006870-f5w6fw6q 2480 10 used use VBN cord-006870-f5w6fw6q 2480 11 in in IN cord-006870-f5w6fw6q 2480 12 lieu lieu NN cord-006870-f5w6fw6q 2480 13 of of IN cord-006870-f5w6fw6q 2480 14 indirect indirect JJ cord-006870-f5w6fw6q 2480 15 calorimetry calorimetry NN cord-006870-f5w6fw6q 2480 16 ( ( -LRB- cord-006870-f5w6fw6q 2480 17 IC IC NNP cord-006870-f5w6fw6q 2480 18 ) ) -RRB- cord-006870-f5w6fw6q 2480 19 due due IN cord-006870-f5w6fw6q 2480 20 to to TO cord-006870-f5w6fw6q 2480 21 cost cost NN cord-006870-f5w6fw6q 2480 22 and and CC cord-006870-f5w6fw6q 2480 23 limited limited JJ cord-006870-f5w6fw6q 2480 24 resources resource NNS cord-006870-f5w6fw6q 2480 25 ; ; : cord-006870-f5w6fw6q 2480 26 however however RB cord-006870-f5w6fw6q 2480 27 , , , cord-006870-f5w6fw6q 2480 28 these these DT cord-006870-f5w6fw6q 2480 29 equations equation NNS cord-006870-f5w6fw6q 2480 30 may may MD cord-006870-f5w6fw6q 2480 31 not not RB cord-006870-f5w6fw6q 2480 32 be be VB cord-006870-f5w6fw6q 2480 33 as as RB cord-006870-f5w6fw6q 2480 34 accurate accurate JJ cord-006870-f5w6fw6q 2480 35 as as IN cord-006870-f5w6fw6q 2480 36 IC IC NNP cord-006870-f5w6fw6q 2480 37 in in IN cord-006870-f5w6fw6q 2480 38 estimating estimate VBG cord-006870-f5w6fw6q 2480 39 resting rest VBG cord-006870-f5w6fw6q 2480 40 energy energy NN cord-006870-f5w6fw6q 2480 41 expenditure expenditure NN cord-006870-f5w6fw6q 2480 42 ( ( -LRB- cord-006870-f5w6fw6q 2480 43 REE REE NNP cord-006870-f5w6fw6q 2480 44 ) ) -RRB- cord-006870-f5w6fw6q 2480 45 in in IN cord-006870-f5w6fw6q 2480 46 critically critically RB cord-006870-f5w6fw6q 2480 47 ill ill JJ cord-006870-f5w6fw6q 2480 48 patients patient NNS cord-006870-f5w6fw6q 2480 49 . . . cord-006870-f5w6fw6q 2481 1 The the DT cord-006870-f5w6fw6q 2481 2 purpose purpose NN cord-006870-f5w6fw6q 2481 3 of of IN cord-006870-f5w6fw6q 2481 4 this this DT cord-006870-f5w6fw6q 2481 5 study study NN cord-006870-f5w6fw6q 2481 6 is be VBZ cord-006870-f5w6fw6q 2481 7 to to TO cord-006870-f5w6fw6q 2481 8 compare compare VB cord-006870-f5w6fw6q 2481 9 PEE PEE NNP cord-006870-f5w6fw6q 2481 10 and and CC cord-006870-f5w6fw6q 2481 11 measured measure VBN cord-006870-f5w6fw6q 2481 12 energy energy NN cord-006870-f5w6fw6q 2481 13 expenditure expenditure NN cord-006870-f5w6fw6q 2481 14 ( ( -LRB- cord-006870-f5w6fw6q 2481 15 MEE MEE NNP cord-006870-f5w6fw6q 2481 16 ) ) -RRB- cord-006870-f5w6fw6q 2481 17 in in IN cord-006870-f5w6fw6q 2481 18 critically critically RB cord-006870-f5w6fw6q 2481 19 ill ill JJ cord-006870-f5w6fw6q 2481 20 adults adult NNS cord-006870-f5w6fw6q 2481 21 with with IN cord-006870-f5w6fw6q 2481 22 acute acute JJ cord-006870-f5w6fw6q 2481 23 brain brain NN cord-006870-f5w6fw6q 2481 24 injury injury NN cord-006870-f5w6fw6q 2481 25 . . . cord-006870-f5w6fw6q 2482 1 This this DT cord-006870-f5w6fw6q 2482 2 was be VBD cord-006870-f5w6fw6q 2482 3 a a DT cord-006870-f5w6fw6q 2482 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2482 5 review review NN cord-006870-f5w6fw6q 2482 6 of of IN cord-006870-f5w6fw6q 2482 7 adult adult NN cord-006870-f5w6fw6q 2482 8 patients patient NNS cord-006870-f5w6fw6q 2482 9 admitted admit VBN cord-006870-f5w6fw6q 2482 10 with with IN cord-006870-f5w6fw6q 2482 11 acute acute JJ cord-006870-f5w6fw6q 2482 12 brain brain NN cord-006870-f5w6fw6q 2482 13 injury injury NN cord-006870-f5w6fw6q 2482 14 between between IN cord-006870-f5w6fw6q 2482 15 May May NNP cord-006870-f5w6fw6q 2482 16 1st 1st NN cord-006870-f5w6fw6q 2482 17 , , , cord-006870-f5w6fw6q 2482 18 2014 2014 CD cord-006870-f5w6fw6q 2482 19 and and CC cord-006870-f5w6fw6q 2482 20 April April NNP cord-006870-f5w6fw6q 2482 21 1st 1st NN cord-006870-f5w6fw6q 2482 22 , , , cord-006870-f5w6fw6q 2482 23 2016 2016 CD cord-006870-f5w6fw6q 2482 24 who who WP cord-006870-f5w6fw6q 2482 25 had have VBD cord-006870-f5w6fw6q 2482 26 IC IC NNP cord-006870-f5w6fw6q 2482 27 performed perform VBN cord-006870-f5w6fw6q 2482 28 . . . cord-006870-f5w6fw6q 2483 1 Three three CD cord-006870-f5w6fw6q 2483 2 predictive predictive JJ cord-006870-f5w6fw6q 2483 3 equations equation NNS cord-006870-f5w6fw6q 2483 4 ( ( -LRB- cord-006870-f5w6fw6q 2483 5 PE PE NNP cord-006870-f5w6fw6q 2483 6 ) ) -RRB- cord-006870-f5w6fw6q 2483 7 , , , cord-006870-f5w6fw6q 2483 8 Harris Harris NNP cord-006870-f5w6fw6q 2483 9 Benedict Benedict NNP cord-006870-f5w6fw6q 2483 10 ( ( -LRB- cord-006870-f5w6fw6q 2483 11 HBE HBE NNP cord-006870-f5w6fw6q 2483 12 ) ) -RRB- cord-006870-f5w6fw6q 2483 13 , , , cord-006870-f5w6fw6q 2483 14 Penn Penn NNP cord-006870-f5w6fw6q 2483 15 State State NNP cord-006870-f5w6fw6q 2483 16 University University NNP cord-006870-f5w6fw6q 2483 17 , , , cord-006870-f5w6fw6q 2483 18 and and CC cord-006870-f5w6fw6q 2483 19 Mifflin Mifflin NNP cord-006870-f5w6fw6q 2483 20 St St NNP cord-006870-f5w6fw6q 2483 21 Jeor Jeor NNP cord-006870-f5w6fw6q 2483 22 ( ( -LRB- cord-006870-f5w6fw6q 2483 23 MSJ MSJ NNP cord-006870-f5w6fw6q 2483 24 ) ) -RRB- cord-006870-f5w6fw6q 2483 25 , , , cord-006870-f5w6fw6q 2483 26 were be VBD cord-006870-f5w6fw6q 2483 27 used use VBN cord-006870-f5w6fw6q 2483 28 in in IN cord-006870-f5w6fw6q 2483 29 comparison comparison NN cord-006870-f5w6fw6q 2483 30 to to IN cord-006870-f5w6fw6q 2483 31 IC IC NNP cord-006870-f5w6fw6q 2483 32 results result NNS cord-006870-f5w6fw6q 2483 33 . . . cord-006870-f5w6fw6q 2484 1 Subgroup subgroup NN cord-006870-f5w6fw6q 2484 2 analyses analysis NNS cord-006870-f5w6fw6q 2484 3 included include VBD cord-006870-f5w6fw6q 2484 4 a a DT cord-006870-f5w6fw6q 2484 5 modified modify VBN cord-006870-f5w6fw6q 2484 6 ASPEN aspen NN cord-006870-f5w6fw6q 2484 7 weight weight NN cord-006870-f5w6fw6q 2484 8 - - HYPH cord-006870-f5w6fw6q 2484 9 based base VBN cord-006870-f5w6fw6q 2484 10 equation equation NN cord-006870-f5w6fw6q 2484 11 , , , cord-006870-f5w6fw6q 2484 12 stratifying stratify VBG cord-006870-f5w6fw6q 2484 13 patients patient NNS cord-006870-f5w6fw6q 2484 14 based base VBN cord-006870-f5w6fw6q 2484 15 on on IN cord-006870-f5w6fw6q 2484 16 BMI bmi NN cord-006870-f5w6fw6q 2484 17 and and CC cord-006870-f5w6fw6q 2484 18 type type NN cord-006870-f5w6fw6q 2484 19 of of IN cord-006870-f5w6fw6q 2484 20 acute acute JJ cord-006870-f5w6fw6q 2484 21 brain brain NN cord-006870-f5w6fw6q 2484 22 injury injury NN cord-006870-f5w6fw6q 2484 23 . . . cord-006870-f5w6fw6q 2485 1 144 144 CD cord-006870-f5w6fw6q 2485 2 patients patient NNS cord-006870-f5w6fw6q 2485 3 met meet VBD cord-006870-f5w6fw6q 2485 4 inclusion inclusion NN cord-006870-f5w6fw6q 2485 5 criteria criterion NNS cord-006870-f5w6fw6q 2485 6 . . . cord-006870-f5w6fw6q 2486 1 Comparing compare VBG cord-006870-f5w6fw6q 2486 2 the the DT cord-006870-f5w6fw6q 2486 3 PEE PEE NNP cord-006870-f5w6fw6q 2486 4 estimated estimate VBN cord-006870-f5w6fw6q 2486 5 by by IN cord-006870-f5w6fw6q 2486 6 the the DT cord-006870-f5w6fw6q 2486 7 three three CD cord-006870-f5w6fw6q 2486 8 predictive predictive JJ cord-006870-f5w6fw6q 2486 9 equations equation NNS cord-006870-f5w6fw6q 2486 10 to to IN cord-006870-f5w6fw6q 2486 11 the the DT cord-006870-f5w6fw6q 2486 12 MEE MEE NNP cord-006870-f5w6fw6q 2486 13 from from IN cord-006870-f5w6fw6q 2486 14 IC IC NNP cord-006870-f5w6fw6q 2486 15 found find VBD cord-006870-f5w6fw6q 2486 16 no no DT cord-006870-f5w6fw6q 2486 17 significant significant JJ cord-006870-f5w6fw6q 2486 18 difference difference NN cord-006870-f5w6fw6q 2486 19 . . . cord-006870-f5w6fw6q 2487 1 High high JJ cord-006870-f5w6fw6q 2487 2 degrees degree NNS cord-006870-f5w6fw6q 2487 3 of of IN cord-006870-f5w6fw6q 2487 4 interpatient interpatient NN cord-006870-f5w6fw6q 2487 5 variability variability NN cord-006870-f5w6fw6q 2487 6 were be VBD cord-006870-f5w6fw6q 2487 7 discovered discover VBN cord-006870-f5w6fw6q 2487 8 in in IN cord-006870-f5w6fw6q 2487 9 each each DT cord-006870-f5w6fw6q 2487 10 ANOVA ANOVA NNP cord-006870-f5w6fw6q 2487 11 analysis analysis NN cord-006870-f5w6fw6q 2487 12 , , , cord-006870-f5w6fw6q 2487 13 with with IN cord-006870-f5w6fw6q 2487 14 standard standard JJ cord-006870-f5w6fw6q 2487 15 deviations deviation NNS cord-006870-f5w6fw6q 2487 16 ranging range VBG cord-006870-f5w6fw6q 2487 17 from from IN cord-006870-f5w6fw6q 2487 18 17 17 CD cord-006870-f5w6fw6q 2487 19 -29 -29 CD cord-006870-f5w6fw6q 2487 20 % % NN cord-006870-f5w6fw6q 2487 21 . . . cord-006870-f5w6fw6q 2488 1 Despite despite IN cord-006870-f5w6fw6q 2488 2 no no DT cord-006870-f5w6fw6q 2488 3 difference difference NN cord-006870-f5w6fw6q 2488 4 found find VBN cord-006870-f5w6fw6q 2488 5 among among IN cord-006870-f5w6fw6q 2488 6 PEE PEE NNP cord-006870-f5w6fw6q 2488 7 and and CC cord-006870-f5w6fw6q 2488 8 MEE MEE NNP cord-006870-f5w6fw6q 2488 9 , , , cord-006870-f5w6fw6q 2488 10 Pearson Pearson NNP cord-006870-f5w6fw6q 2488 11 's 's POS cord-006870-f5w6fw6q 2488 12 correlations correlation NNS cord-006870-f5w6fw6q 2488 13 indicated indicate VBD cord-006870-f5w6fw6q 2488 14 weak weak JJ cord-006870-f5w6fw6q 2488 15 associations association NNS cord-006870-f5w6fw6q 2488 16 when when WRB cord-006870-f5w6fw6q 2488 17 HBE HBE NNP cord-006870-f5w6fw6q 2488 18 , , , cord-006870-f5w6fw6q 2488 19 Penn Penn NNP cord-006870-f5w6fw6q 2488 20 State State NNP cord-006870-f5w6fw6q 2488 21 , , , cord-006870-f5w6fw6q 2488 22 and and CC cord-006870-f5w6fw6q 2488 23 MSJ MSJ NNP cord-006870-f5w6fw6q 2488 24 were be VBD cord-006870-f5w6fw6q 2488 25 individually individually RB cord-006870-f5w6fw6q 2488 26 compared compare VBN cord-006870-f5w6fw6q 2488 27 to to IN cord-006870-f5w6fw6q 2488 28 MEE MEE NNP cord-006870-f5w6fw6q 2488 29 ( ( -LRB- cord-006870-f5w6fw6q 2488 30 r r NN cord-006870-f5w6fw6q 2488 31 - - HYPH cord-006870-f5w6fw6q 2488 32 values value NNS cord-006870-f5w6fw6q 2488 33 = = SYM cord-006870-f5w6fw6q 2488 34 0.372 0.372 CD cord-006870-f5w6fw6q 2488 35 , , , cord-006870-f5w6fw6q 2488 36 0.409 0.409 CD cord-006870-f5w6fw6q 2488 37 , , , cord-006870-f5w6fw6q 2488 38 and and CC cord-006870-f5w6fw6q 2488 39 0.372 0.372 CD cord-006870-f5w6fw6q 2488 40 , , , cord-006870-f5w6fw6q 2488 41 respectively respectively RB cord-006870-f5w6fw6q 2488 42 ) ) -RRB- cord-006870-f5w6fw6q 2488 43 . . . cord-006870-f5w6fw6q 2489 1 In in IN cord-006870-f5w6fw6q 2489 2 patients patient NNS cord-006870-f5w6fw6q 2489 3 with with IN cord-006870-f5w6fw6q 2489 4 a a DT cord-006870-f5w6fw6q 2489 5 BMI BMI NNP cord-006870-f5w6fw6q 2489 6 < < XX cord-006870-f5w6fw6q 2489 7 30 30 CD cord-006870-f5w6fw6q 2489 8 kg kg NNP cord-006870-f5w6fw6q 2489 9 / / SYM cord-006870-f5w6fw6q 2489 10 m2 m2 NNP cord-006870-f5w6fw6q 2489 11 , , , cord-006870-f5w6fw6q 2489 12 a a DT cord-006870-f5w6fw6q 2489 13 significant significant JJ cord-006870-f5w6fw6q 2489 14 difference difference NN cord-006870-f5w6fw6q 2489 15 was be VBD cord-006870-f5w6fw6q 2489 16 found find VBN cord-006870-f5w6fw6q 2489 17 ( ( -LRB- cord-006870-f5w6fw6q 2489 18 p p NN cord-006870-f5w6fw6q 2489 19 - - HYPH cord-006870-f5w6fw6q 2489 20 value=0.0006 value=0.0006 NNP cord-006870-f5w6fw6q 2489 21 ) ) -RRB- cord-006870-f5w6fw6q 2489 22 with with IN cord-006870-f5w6fw6q 2489 23 PEE pee NN cord-006870-f5w6fw6q 2489 24 underestimating underestimate VBG cord-006870-f5w6fw6q 2489 25 the the DT cord-006870-f5w6fw6q 2489 26 REE ree NN cord-006870-f5w6fw6q 2489 27 . . . cord-006870-f5w6fw6q 2490 1 Additionally additionally RB cord-006870-f5w6fw6q 2490 2 , , , cord-006870-f5w6fw6q 2490 3 In in IN cord-006870-f5w6fw6q 2490 4 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 2490 5 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2490 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2490 7 a a DT cord-006870-f5w6fw6q 2490 8 significant significant JJ cord-006870-f5w6fw6q 2490 9 difference difference NN cord-006870-f5w6fw6q 2490 10 was be VBD cord-006870-f5w6fw6q 2490 11 observed observe VBN cord-006870-f5w6fw6q 2490 12 between between IN cord-006870-f5w6fw6q 2490 13 PEE PEE NNP cord-006870-f5w6fw6q 2490 14 and and CC cord-006870-f5w6fw6q 2490 15 MEE MEE NNP cord-006870-f5w6fw6q 2490 16 ( ( -LRB- cord-006870-f5w6fw6q 2490 17 p p NN cord-006870-f5w6fw6q 2490 18 - - : cord-006870-f5w6fw6q 2490 19 value=0.005 value=0.005 NNP cord-006870-f5w6fw6q 2490 20 ) ) -RRB- cord-006870-f5w6fw6q 2490 21 . . . cord-006870-f5w6fw6q 2491 1 The the DT cord-006870-f5w6fw6q 2491 2 results result NNS cord-006870-f5w6fw6q 2491 3 of of IN cord-006870-f5w6fw6q 2491 4 this this DT cord-006870-f5w6fw6q 2491 5 study study NN cord-006870-f5w6fw6q 2491 6 highlight highlight VB cord-006870-f5w6fw6q 2491 7 the the DT cord-006870-f5w6fw6q 2491 8 importance importance NN cord-006870-f5w6fw6q 2491 9 of of IN cord-006870-f5w6fw6q 2491 10 using use VBG cord-006870-f5w6fw6q 2491 11 IC IC NNP cord-006870-f5w6fw6q 2491 12 whenever whenever WRB cord-006870-f5w6fw6q 2491 13 feasible feasible JJ cord-006870-f5w6fw6q 2491 14 due due IN cord-006870-f5w6fw6q 2491 15 to to IN cord-006870-f5w6fw6q 2491 16 the the DT cord-006870-f5w6fw6q 2491 17 interpatient interpatient NN cord-006870-f5w6fw6q 2491 18 variability variability NN cord-006870-f5w6fw6q 2491 19 of of IN cord-006870-f5w6fw6q 2491 20 the the DT cord-006870-f5w6fw6q 2491 21 REE ree NN cord-006870-f5w6fw6q 2491 22 of of IN cord-006870-f5w6fw6q 2491 23 critically critically RB cord-006870-f5w6fw6q 2491 24 ill ill JJ cord-006870-f5w6fw6q 2491 25 patients patient NNS cord-006870-f5w6fw6q 2491 26 with with IN cord-006870-f5w6fw6q 2491 27 acute acute JJ cord-006870-f5w6fw6q 2491 28 brain brain NN cord-006870-f5w6fw6q 2491 29 injury injury NN cord-006870-f5w6fw6q 2491 30 . . . cord-006870-f5w6fw6q 2492 1 Although although IN cord-006870-f5w6fw6q 2492 2 predicative predicative JJ cord-006870-f5w6fw6q 2492 3 equations equation NNS cord-006870-f5w6fw6q 2492 4 appear appear VBP cord-006870-f5w6fw6q 2492 5 to to TO cord-006870-f5w6fw6q 2492 6 have have VB cord-006870-f5w6fw6q 2492 7 similar similar JJ cord-006870-f5w6fw6q 2492 8 estimations estimation NNS cord-006870-f5w6fw6q 2492 9 as as IN cord-006870-f5w6fw6q 2492 10 IC IC NNP cord-006870-f5w6fw6q 2492 11 , , , cord-006870-f5w6fw6q 2492 12 interpatient interpatient NN cord-006870-f5w6fw6q 2492 13 variability variability NN cord-006870-f5w6fw6q 2492 14 warrants warrant NNS cord-006870-f5w6fw6q 2492 15 more more RBR cord-006870-f5w6fw6q 2492 16 accurate accurate JJ cord-006870-f5w6fw6q 2492 17 measurement measurement NN cord-006870-f5w6fw6q 2492 18 with with IN cord-006870-f5w6fw6q 2492 19 IC IC NNP cord-006870-f5w6fw6q 2492 20 to to TO cord-006870-f5w6fw6q 2492 21 optimize optimize VB cord-006870-f5w6fw6q 2492 22 nutrition nutrition NN cord-006870-f5w6fw6q 2492 23 in in IN cord-006870-f5w6fw6q 2492 24 patients patient NNS cord-006870-f5w6fw6q 2492 25 with with IN cord-006870-f5w6fw6q 2492 26 acute acute JJ cord-006870-f5w6fw6q 2492 27 brain brain NN cord-006870-f5w6fw6q 2492 28 injury injury NN cord-006870-f5w6fw6q 2492 29 . . . cord-006870-f5w6fw6q 2493 1 Introduction introduction NN cord-006870-f5w6fw6q 2493 2 4-Factor 4-factor CD cord-006870-f5w6fw6q 2494 1 prothrombin prothrombin NN cord-006870-f5w6fw6q 2494 2 complex complex NN cord-006870-f5w6fw6q 2494 3 concentrate concentrate NN cord-006870-f5w6fw6q 2494 4 ( ( -LRB- cord-006870-f5w6fw6q 2494 5 PCC PCC NNP cord-006870-f5w6fw6q 2494 6 ) ) -RRB- cord-006870-f5w6fw6q 2494 7 should should MD cord-006870-f5w6fw6q 2494 8 be be VB cord-006870-f5w6fw6q 2494 9 administered administer VBN cord-006870-f5w6fw6q 2494 10 as as RB cord-006870-f5w6fw6q 2494 11 soon soon RB cord-006870-f5w6fw6q 2494 12 as as IN cord-006870-f5w6fw6q 2494 13 possible possible JJ cord-006870-f5w6fw6q 2494 14 for for IN cord-006870-f5w6fw6q 2494 15 reversal reversal NN cord-006870-f5w6fw6q 2494 16 of of IN cord-006870-f5w6fw6q 2494 17 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2494 18 in in IN cord-006870-f5w6fw6q 2494 19 the the DT cord-006870-f5w6fw6q 2494 20 setting setting NN cord-006870-f5w6fw6q 2494 21 of of IN cord-006870-f5w6fw6q 2494 22 life life NN cord-006870-f5w6fw6q 2494 23 - - HYPH cord-006870-f5w6fw6q 2494 24 threatening threaten VBG cord-006870-f5w6fw6q 2494 25 bleeding bleeding NN cord-006870-f5w6fw6q 2494 26 or or CC cord-006870-f5w6fw6q 2494 27 urgent urgent JJ cord-006870-f5w6fw6q 2494 28 procedures procedure NNS cord-006870-f5w6fw6q 2494 29 . . . cord-006870-f5w6fw6q 2495 1 Limited limited JJ cord-006870-f5w6fw6q 2495 2 information information NN cord-006870-f5w6fw6q 2495 3 is be VBZ cord-006870-f5w6fw6q 2495 4 available available JJ cord-006870-f5w6fw6q 2495 5 on on IN cord-006870-f5w6fw6q 2495 6 the the DT cord-006870-f5w6fw6q 2495 7 safety safety NN cord-006870-f5w6fw6q 2495 8 , , , cord-006870-f5w6fw6q 2495 9 efficacy efficacy NN cord-006870-f5w6fw6q 2495 10 , , , cord-006870-f5w6fw6q 2495 11 and and CC cord-006870-f5w6fw6q 2495 12 time time NN cord-006870-f5w6fw6q 2495 13 to to IN cord-006870-f5w6fw6q 2495 14 administration administration NN cord-006870-f5w6fw6q 2495 15 of of IN cord-006870-f5w6fw6q 2495 16 PCC PCC NNP cord-006870-f5w6fw6q 2495 17 when when WRB cord-006870-f5w6fw6q 2495 18 administered administer VBN cord-006870-f5w6fw6q 2495 19 at at IN cord-006870-f5w6fw6q 2495 20 high high JJ cord-006870-f5w6fw6q 2495 21 infusion infusion NN cord-006870-f5w6fw6q 2495 22 rates rate NNS cord-006870-f5w6fw6q 2495 23 . . . cord-006870-f5w6fw6q 2496 1 On on IN cord-006870-f5w6fw6q 2496 2 March March NNP cord-006870-f5w6fw6q 2496 3 21 21 CD cord-006870-f5w6fw6q 2496 4 , , , cord-006870-f5w6fw6q 2496 5 2017 2017 CD cord-006870-f5w6fw6q 2496 6 Grady Grady NNP cord-006870-f5w6fw6q 2496 7 Health Health NNP cord-006870-f5w6fw6q 2496 8 System System NNP cord-006870-f5w6fw6q 2496 9 implemented implement VBD cord-006870-f5w6fw6q 2496 10 a a DT cord-006870-f5w6fw6q 2496 11 rapid rapid JJ cord-006870-f5w6fw6q 2496 12 PCC PCC NNP cord-006870-f5w6fw6q 2496 13 administration administration NN cord-006870-f5w6fw6q 2496 14 strategy strategy NN cord-006870-f5w6fw6q 2496 15 while while IN cord-006870-f5w6fw6q 2496 16 attempting attempt VBG cord-006870-f5w6fw6q 2496 17 to to TO cord-006870-f5w6fw6q 2496 18 reduce reduce VB cord-006870-f5w6fw6q 2496 19 times time NNS cord-006870-f5w6fw6q 2496 20 from from IN cord-006870-f5w6fw6q 2496 21 order order NN cord-006870-f5w6fw6q 2496 22 entry entry NN cord-006870-f5w6fw6q 2496 23 to to IN cord-006870-f5w6fw6q 2496 24 administration administration NN cord-006870-f5w6fw6q 2496 25 as as IN cord-006870-f5w6fw6q 2496 26 a a DT cord-006870-f5w6fw6q 2496 27 quality quality NN cord-006870-f5w6fw6q 2496 28 improvement improvement NN cord-006870-f5w6fw6q 2496 29 initiative initiative NN cord-006870-f5w6fw6q 2496 30 . . . cord-006870-f5w6fw6q 2497 1 This this DT cord-006870-f5w6fw6q 2497 2 IRB IRB NNP cord-006870-f5w6fw6q 2497 3 - - HYPH cord-006870-f5w6fw6q 2497 4 approved approve VBN cord-006870-f5w6fw6q 2497 5 , , , cord-006870-f5w6fw6q 2497 6 retrospective retrospective JJ cord-006870-f5w6fw6q 2497 7 evaluation evaluation NN cord-006870-f5w6fw6q 2497 8 includes include VBZ cord-006870-f5w6fw6q 2497 9 PCC PCC NNP cord-006870-f5w6fw6q 2497 10 administrations administration NNS cord-006870-f5w6fw6q 2497 11 90 90 CD cord-006870-f5w6fw6q 2497 12 days day NNS cord-006870-f5w6fw6q 2497 13 pre pre VBP cord-006870-f5w6fw6q 2497 14 - - JJ cord-006870-f5w6fw6q 2497 15 and and CC cord-006870-f5w6fw6q 2497 16 post post JJ cord-006870-f5w6fw6q 2497 17 - - JJ cord-006870-f5w6fw6q 2497 18 protocol protocol JJ cord-006870-f5w6fw6q 2497 19 implementation implementation NN cord-006870-f5w6fw6q 2497 20 . . . cord-006870-f5w6fw6q 2498 1 After after IN cord-006870-f5w6fw6q 2498 2 protocol protocol NN cord-006870-f5w6fw6q 2498 3 implementation implementation NN cord-006870-f5w6fw6q 2498 4 , , , cord-006870-f5w6fw6q 2498 5 PCC PCC NNP cord-006870-f5w6fw6q 2498 6 doses dose NNS cord-006870-f5w6fw6q 2498 7 were be VBD cord-006870-f5w6fw6q 2498 8 prepared prepare VBN cord-006870-f5w6fw6q 2498 9 in in IN cord-006870-f5w6fw6q 2498 10 up up IN cord-006870-f5w6fw6q 2498 11 to to TO cord-006870-f5w6fw6q 2498 12 four four CD cord-006870-f5w6fw6q 2498 13 , , , cord-006870-f5w6fw6q 2498 14 60-mL 60-ml CD cord-006870-f5w6fw6q 2498 15 syringes syrinx NNS cord-006870-f5w6fw6q 2498 16 , , , cord-006870-f5w6fw6q 2498 17 dependent dependent JJ cord-006870-f5w6fw6q 2498 18 on on IN cord-006870-f5w6fw6q 2498 19 the the DT cord-006870-f5w6fw6q 2498 20 ordered order VBN cord-006870-f5w6fw6q 2498 21 dose dose NN cord-006870-f5w6fw6q 2498 22 . . . cord-006870-f5w6fw6q 2499 1 Each each DT cord-006870-f5w6fw6q 2499 2 syringe syringe NN cord-006870-f5w6fw6q 2499 3 was be VBD cord-006870-f5w6fw6q 2499 4 administered administer VBN cord-006870-f5w6fw6q 2499 5 over over IN cord-006870-f5w6fw6q 2499 6 2 2 CD cord-006870-f5w6fw6q 2499 7 minutes minute NNS cord-006870-f5w6fw6q 2499 8 , , , cord-006870-f5w6fw6q 2499 9 not not RB cord-006870-f5w6fw6q 2499 10 exceeding exceed VBG cord-006870-f5w6fw6q 2499 11 a a DT cord-006870-f5w6fw6q 2499 12 rate rate NN cord-006870-f5w6fw6q 2499 13 of of IN cord-006870-f5w6fw6q 2499 14 750 750 CD cord-006870-f5w6fw6q 2499 15 IU IU NNP cord-006870-f5w6fw6q 2499 16 / / SYM cord-006870-f5w6fw6q 2499 17 minute minute NN cord-006870-f5w6fw6q 2499 18 . . . cord-006870-f5w6fw6q 2500 1 The the DT cord-006870-f5w6fw6q 2500 2 primary primary JJ cord-006870-f5w6fw6q 2500 3 objective objective NN cord-006870-f5w6fw6q 2500 4 of of IN cord-006870-f5w6fw6q 2500 5 this this DT cord-006870-f5w6fw6q 2500 6 study study NN cord-006870-f5w6fw6q 2500 7 is be VBZ cord-006870-f5w6fw6q 2500 8 to to TO cord-006870-f5w6fw6q 2500 9 evaluate evaluate VB cord-006870-f5w6fw6q 2500 10 the the DT cord-006870-f5w6fw6q 2500 11 safety safety NN cord-006870-f5w6fw6q 2500 12 of of IN cord-006870-f5w6fw6q 2500 13 a a DT cord-006870-f5w6fw6q 2500 14 rapid rapid JJ cord-006870-f5w6fw6q 2500 15 administration administration NN cord-006870-f5w6fw6q 2500 16 strategy strategy NN cord-006870-f5w6fw6q 2500 17 for for IN cord-006870-f5w6fw6q 2500 18 PCC PCC NNP cord-006870-f5w6fw6q 2500 19 . . . cord-006870-f5w6fw6q 2501 1 Secondary secondary JJ cord-006870-f5w6fw6q 2501 2 objectives objective NNS cord-006870-f5w6fw6q 2501 3 include include VBP cord-006870-f5w6fw6q 2501 4 turn turn NN cord-006870-f5w6fw6q 2501 5 - - HYPH cord-006870-f5w6fw6q 2501 6 around around RP cord-006870-f5w6fw6q 2501 7 times time NNS cord-006870-f5w6fw6q 2501 8 and and CC cord-006870-f5w6fw6q 2501 9 effectiveness effectiveness NN cord-006870-f5w6fw6q 2501 10 of of IN cord-006870-f5w6fw6q 2501 11 INR INR NNP cord-006870-f5w6fw6q 2501 12 reversal reversal NN cord-006870-f5w6fw6q 2501 13 in in IN cord-006870-f5w6fw6q 2501 14 patients patient NNS cord-006870-f5w6fw6q 2501 15 previously previously RB cord-006870-f5w6fw6q 2501 16 on on IN cord-006870-f5w6fw6q 2501 17 warfarin warfarin NN cord-006870-f5w6fw6q 2501 18 . . . cord-006870-f5w6fw6q 2502 1 Results result NNS cord-006870-f5w6fw6q 2502 2 52 52 CD cord-006870-f5w6fw6q 2502 3 unique unique JJ cord-006870-f5w6fw6q 2502 4 PCC PCC NNP cord-006870-f5w6fw6q 2502 5 administrations administration NNS cord-006870-f5w6fw6q 2502 6 were be VBD cord-006870-f5w6fw6q 2502 7 identified identify VBN cord-006870-f5w6fw6q 2502 8 : : : cord-006870-f5w6fw6q 2502 9 29 29 CD cord-006870-f5w6fw6q 2502 10 administrations administration NNS cord-006870-f5w6fw6q 2502 11 in in IN cord-006870-f5w6fw6q 2502 12 the the DT cord-006870-f5w6fw6q 2502 13 pre pre NN cord-006870-f5w6fw6q 2502 14 - - JJ cord-006870-f5w6fw6q 2502 15 cohort cohort JJ cord-006870-f5w6fw6q 2502 16 and and CC cord-006870-f5w6fw6q 2502 17 23 23 CD cord-006870-f5w6fw6q 2502 18 in in IN cord-006870-f5w6fw6q 2502 19 the the DT cord-006870-f5w6fw6q 2502 20 postimplementation postimplementation NN cord-006870-f5w6fw6q 2502 21 cohort cohort NN cord-006870-f5w6fw6q 2502 22 . . . cord-006870-f5w6fw6q 2503 1 Most Most JJS cord-006870-f5w6fw6q 2503 2 PCC PCC NNP cord-006870-f5w6fw6q 2503 3 administrations administration NNS cord-006870-f5w6fw6q 2503 4 were be VBD cord-006870-f5w6fw6q 2503 5 in in IN cord-006870-f5w6fw6q 2503 6 the the DT cord-006870-f5w6fw6q 2503 7 setting setting NN cord-006870-f5w6fw6q 2503 8 of of IN cord-006870-f5w6fw6q 2503 9 spontaneous spontaneous JJ cord-006870-f5w6fw6q 2503 10 or or CC cord-006870-f5w6fw6q 2503 11 traumatic traumatic JJ cord-006870-f5w6fw6q 2503 12 intracranial intracranial JJ cord-006870-f5w6fw6q 2503 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2503 14 . . . cord-006870-f5w6fw6q 2504 1 There there EX cord-006870-f5w6fw6q 2504 2 were be VBD cord-006870-f5w6fw6q 2504 3 no no DT cord-006870-f5w6fw6q 2504 4 infusion infusion NN cord-006870-f5w6fw6q 2504 5 - - HYPH cord-006870-f5w6fw6q 2504 6 related relate VBN cord-006870-f5w6fw6q 2504 7 adverse adverse JJ cord-006870-f5w6fw6q 2504 8 events event NNS cord-006870-f5w6fw6q 2504 9 documented document VBN cord-006870-f5w6fw6q 2504 10 with with IN cord-006870-f5w6fw6q 2504 11 the the DT cord-006870-f5w6fw6q 2504 12 exception exception NN cord-006870-f5w6fw6q 2504 13 of of IN cord-006870-f5w6fw6q 2504 14 a a DT cord-006870-f5w6fw6q 2504 15 possible possible JJ cord-006870-f5w6fw6q 2504 16 PCC PCC NNP cord-006870-f5w6fw6q 2504 17 infiltration infiltration NN cord-006870-f5w6fw6q 2504 18 post post NN cord-006870-f5w6fw6q 2504 19 - - NN cord-006870-f5w6fw6q 2504 20 implementation implementation NN cord-006870-f5w6fw6q 2504 21 which which WDT cord-006870-f5w6fw6q 2504 22 resolved resolve VBD cord-006870-f5w6fw6q 2504 23 with with IN cord-006870-f5w6fw6q 2504 24 supportive supportive JJ cord-006870-f5w6fw6q 2504 25 care care NN cord-006870-f5w6fw6q 2504 26 only only RB cord-006870-f5w6fw6q 2504 27 . . . cord-006870-f5w6fw6q 2505 1 The the DT cord-006870-f5w6fw6q 2505 2 median median JJ cord-006870-f5w6fw6q 2505 3 order order NN cord-006870-f5w6fw6q 2505 4 entry entry NN cord-006870-f5w6fw6q 2505 5 to to IN cord-006870-f5w6fw6q 2505 6 administration administration NN cord-006870-f5w6fw6q 2505 7 time time NN cord-006870-f5w6fw6q 2505 8 was be VBD cord-006870-f5w6fw6q 2505 9 higher high JJR cord-006870-f5w6fw6q 2505 10 in in IN cord-006870-f5w6fw6q 2505 11 the the DT cord-006870-f5w6fw6q 2505 12 post post JJ cord-006870-f5w6fw6q 2505 13 - - JJ cord-006870-f5w6fw6q 2505 14 implementation implementation JJ cord-006870-f5w6fw6q 2505 15 group group NN cord-006870-f5w6fw6q 2505 16 ( ( -LRB- cord-006870-f5w6fw6q 2505 17 52 52 CD cord-006870-f5w6fw6q 2505 18 vs. vs. CC cord-006870-f5w6fw6q 2505 19 42 42 CD cord-006870-f5w6fw6q 2505 20 minutes minute NNS cord-006870-f5w6fw6q 2505 21 ) ) -RRB- cord-006870-f5w6fw6q 2505 22 . . . cord-006870-f5w6fw6q 2506 1 18 18 CD cord-006870-f5w6fw6q 2506 2 administrations administration NNS cord-006870-f5w6fw6q 2506 3 in in IN cord-006870-f5w6fw6q 2506 4 the the DT cord-006870-f5w6fw6q 2506 5 pre pre NN cord-006870-f5w6fw6q 2506 6 - - JJ cord-006870-f5w6fw6q 2506 7 cohort cohort JJ cord-006870-f5w6fw6q 2506 8 and and CC cord-006870-f5w6fw6q 2506 9 11 11 CD cord-006870-f5w6fw6q 2506 10 administrations administration NNS cord-006870-f5w6fw6q 2506 11 in in IN cord-006870-f5w6fw6q 2506 12 the the DT cord-006870-f5w6fw6q 2506 13 post post NN cord-006870-f5w6fw6q 2506 14 - - JJ cord-006870-f5w6fw6q 2506 15 cohort cohort JJ cord-006870-f5w6fw6q 2506 16 were be VBD cord-006870-f5w6fw6q 2506 17 for for IN cord-006870-f5w6fw6q 2506 18 warfarin warfarin JJ cord-006870-f5w6fw6q 2506 19 reversal reversal NN cord-006870-f5w6fw6q 2506 20 . . . cord-006870-f5w6fw6q 2507 1 A a DT cord-006870-f5w6fw6q 2507 2 greater great JJR cord-006870-f5w6fw6q 2507 3 percent percent NN cord-006870-f5w6fw6q 2507 4 of of IN cord-006870-f5w6fw6q 2507 5 patients patient NNS cord-006870-f5w6fw6q 2507 6 previously previously RB cord-006870-f5w6fw6q 2507 7 on on IN cord-006870-f5w6fw6q 2507 8 warfarin warfarin NN cord-006870-f5w6fw6q 2507 9 reversed reverse VBN cord-006870-f5w6fw6q 2507 10 to to IN cord-006870-f5w6fw6q 2507 11 an an DT cord-006870-f5w6fw6q 2507 12 INR INR NNP cord-006870-f5w6fw6q 2507 13 < < XX cord-006870-f5w6fw6q 2507 14 1.4 1.4 CD cord-006870-f5w6fw6q 2507 15 in in IN cord-006870-f5w6fw6q 2507 16 the the DT cord-006870-f5w6fw6q 2507 17 post post JJ cord-006870-f5w6fw6q 2507 18 - - JJ cord-006870-f5w6fw6q 2507 19 cohort cohort JJ cord-006870-f5w6fw6q 2507 20 compared compare VBN cord-006870-f5w6fw6q 2507 21 to to IN cord-006870-f5w6fw6q 2507 22 the the DT cord-006870-f5w6fw6q 2507 23 pre pre NN cord-006870-f5w6fw6q 2507 24 - - JJ cord-006870-f5w6fw6q 2507 25 cohort cohort JJ cord-006870-f5w6fw6q 2507 26 , , , cord-006870-f5w6fw6q 2507 27 81.8 81.8 CD cord-006870-f5w6fw6q 2507 28 % % NN cord-006870-f5w6fw6q 2507 29 vs vs IN cord-006870-f5w6fw6q 2507 30 72.2 72.2 CD cord-006870-f5w6fw6q 2507 31 % % NN cord-006870-f5w6fw6q 2507 32 , , , cord-006870-f5w6fw6q 2507 33 respectively respectively RB cord-006870-f5w6fw6q 2507 34 . . . cord-006870-f5w6fw6q 2508 1 This this DT cord-006870-f5w6fw6q 2508 2 retrospective retrospective JJ cord-006870-f5w6fw6q 2508 3 evaluation evaluation NN cord-006870-f5w6fw6q 2508 4 suggests suggest VBZ cord-006870-f5w6fw6q 2508 5 that that IN cord-006870-f5w6fw6q 2508 6 rapid rapid JJ cord-006870-f5w6fw6q 2508 7 intravenous intravenous JJ cord-006870-f5w6fw6q 2508 8 push push NN cord-006870-f5w6fw6q 2508 9 administration administration NN cord-006870-f5w6fw6q 2508 10 of of IN cord-006870-f5w6fw6q 2508 11 4-factor 4-factor CD cord-006870-f5w6fw6q 2508 12 PCC PCC NNP cord-006870-f5w6fw6q 2508 13 is be VBZ cord-006870-f5w6fw6q 2508 14 safe safe JJ cord-006870-f5w6fw6q 2508 15 and and CC cord-006870-f5w6fw6q 2508 16 effective effective JJ cord-006870-f5w6fw6q 2508 17 . . . cord-006870-f5w6fw6q 2509 1 Time time NN cord-006870-f5w6fw6q 2509 2 to to IN cord-006870-f5w6fw6q 2509 3 administration administration NN cord-006870-f5w6fw6q 2509 4 was be VBD cord-006870-f5w6fw6q 2509 5 longer long JJR cord-006870-f5w6fw6q 2509 6 after after IN cord-006870-f5w6fw6q 2509 7 implementation implementation NN cord-006870-f5w6fw6q 2509 8 of of IN cord-006870-f5w6fw6q 2509 9 rapid rapid JJ cord-006870-f5w6fw6q 2509 10 PCC PCC NNP cord-006870-f5w6fw6q 2509 11 administration administration NN cord-006870-f5w6fw6q 2509 12 and and CC cord-006870-f5w6fw6q 2509 13 may may MD cord-006870-f5w6fw6q 2509 14 have have VB cord-006870-f5w6fw6q 2509 15 been be VBN cord-006870-f5w6fw6q 2509 16 due due JJ cord-006870-f5w6fw6q 2509 17 to to IN cord-006870-f5w6fw6q 2509 18 operational operational JJ cord-006870-f5w6fw6q 2509 19 limitations limitation NNS cord-006870-f5w6fw6q 2509 20 . . . cord-006870-f5w6fw6q 2510 1 ICU ICU NNP cord-006870-f5w6fw6q 2510 2 readmission readmission NN cord-006870-f5w6fw6q 2510 3 is be VBZ cord-006870-f5w6fw6q 2510 4 defined define VBN cord-006870-f5w6fw6q 2510 5 as as IN cord-006870-f5w6fw6q 2510 6 a a DT cord-006870-f5w6fw6q 2510 7 return return NN cord-006870-f5w6fw6q 2510 8 to to IN cord-006870-f5w6fw6q 2510 9 the the DT cord-006870-f5w6fw6q 2510 10 ICU ICU NNP cord-006870-f5w6fw6q 2510 11 during during IN cord-006870-f5w6fw6q 2510 12 the the DT cord-006870-f5w6fw6q 2510 13 same same JJ cord-006870-f5w6fw6q 2510 14 hospital hospital NN cord-006870-f5w6fw6q 2510 15 admission admission NN cord-006870-f5w6fw6q 2510 16 . . . cord-006870-f5w6fw6q 2511 1 There there EX cord-006870-f5w6fw6q 2511 2 are be VBP cord-006870-f5w6fw6q 2511 3 multiple multiple JJ cord-006870-f5w6fw6q 2511 4 studies study NNS cord-006870-f5w6fw6q 2511 5 related relate VBN cord-006870-f5w6fw6q 2511 6 to to IN cord-006870-f5w6fw6q 2511 7 medical medical JJ cord-006870-f5w6fw6q 2511 8 and and CC cord-006870-f5w6fw6q 2511 9 general general JJ cord-006870-f5w6fw6q 2511 10 surgical surgical JJ cord-006870-f5w6fw6q 2511 11 recidivism recidivism NN cord-006870-f5w6fw6q 2511 12 , , , cord-006870-f5w6fw6q 2511 13 however however RB cord-006870-f5w6fw6q 2511 14 there there EX cord-006870-f5w6fw6q 2511 15 is be VBZ cord-006870-f5w6fw6q 2511 16 limited limited JJ cord-006870-f5w6fw6q 2511 17 data datum NNS cord-006870-f5w6fw6q 2511 18 on on IN cord-006870-f5w6fw6q 2511 19 ICU ICU NNP cord-006870-f5w6fw6q 2511 20 readmissions readmission NNS cord-006870-f5w6fw6q 2511 21 following follow VBG cord-006870-f5w6fw6q 2511 22 spine spine NN cord-006870-f5w6fw6q 2511 23 surgery surgery NN cord-006870-f5w6fw6q 2511 24 . . . cord-006870-f5w6fw6q 2512 1 The the DT cord-006870-f5w6fw6q 2512 2 aim aim NN cord-006870-f5w6fw6q 2512 3 of of IN cord-006870-f5w6fw6q 2512 4 this this DT cord-006870-f5w6fw6q 2512 5 study study NN cord-006870-f5w6fw6q 2512 6 was be VBD cord-006870-f5w6fw6q 2512 7 to to TO cord-006870-f5w6fw6q 2512 8 evaluate evaluate VB cord-006870-f5w6fw6q 2512 9 factors factor NNS cord-006870-f5w6fw6q 2512 10 associated associate VBN cord-006870-f5w6fw6q 2512 11 with with IN cord-006870-f5w6fw6q 2512 12 ICU ICU NNP cord-006870-f5w6fw6q 2512 13 readmissions readmission NNS cord-006870-f5w6fw6q 2512 14 following follow VBG cord-006870-f5w6fw6q 2512 15 spine spine NN cord-006870-f5w6fw6q 2512 16 surgery surgery NN cord-006870-f5w6fw6q 2512 17 . . . cord-006870-f5w6fw6q 2513 1 Patients patient NNS cord-006870-f5w6fw6q 2513 2 requiring require VBG cord-006870-f5w6fw6q 2513 3 ICU ICU NNP cord-006870-f5w6fw6q 2513 4 admission admission NN cord-006870-f5w6fw6q 2513 5 following follow VBG cord-006870-f5w6fw6q 2513 6 spine spine NN cord-006870-f5w6fw6q 2513 7 surgery surgery NN cord-006870-f5w6fw6q 2513 8 from from IN cord-006870-f5w6fw6q 2513 9 June June NNP cord-006870-f5w6fw6q 2513 10 2013 2013 CD cord-006870-f5w6fw6q 2513 11 to to IN cord-006870-f5w6fw6q 2513 12 June June NNP cord-006870-f5w6fw6q 2513 13 2017 2017 CD cord-006870-f5w6fw6q 2513 14 were be VBD cord-006870-f5w6fw6q 2513 15 studied study VBN cord-006870-f5w6fw6q 2513 16 . . . cord-006870-f5w6fw6q 2514 1 Variables variable NNS cord-006870-f5w6fw6q 2514 2 included include VBD cord-006870-f5w6fw6q 2514 3 age age NN cord-006870-f5w6fw6q 2514 4 , , , cord-006870-f5w6fw6q 2514 5 gender gender NN cord-006870-f5w6fw6q 2514 6 , , , cord-006870-f5w6fw6q 2514 7 ICU ICU NNP cord-006870-f5w6fw6q 2514 8 and and CC cord-006870-f5w6fw6q 2514 9 hospital hospital NN cord-006870-f5w6fw6q 2514 10 disposition disposition NN cord-006870-f5w6fw6q 2514 11 , , , cord-006870-f5w6fw6q 2514 12 ICU ICU NNP cord-006870-f5w6fw6q 2514 13 and and CC cord-006870-f5w6fw6q 2514 14 hospital hospital NN cord-006870-f5w6fw6q 2514 15 length length NN cord-006870-f5w6fw6q 2514 16 of of IN cord-006870-f5w6fw6q 2514 17 stay stay NN cord-006870-f5w6fw6q 2514 18 , , , cord-006870-f5w6fw6q 2514 19 BMI BMI NNP cord-006870-f5w6fw6q 2514 20 , , , cord-006870-f5w6fw6q 2514 21 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 2514 22 , , , cord-006870-f5w6fw6q 2514 23 surgical surgical JJ cord-006870-f5w6fw6q 2514 24 location location NN cord-006870-f5w6fw6q 2514 25 , , , cord-006870-f5w6fw6q 2514 26 number number NN cord-006870-f5w6fw6q 2514 27 of of IN cord-006870-f5w6fw6q 2514 28 previous previous JJ cord-006870-f5w6fw6q 2514 29 surgeries surgery NNS cord-006870-f5w6fw6q 2514 30 and and CC cord-006870-f5w6fw6q 2514 31 vertebra vertebra NN cord-006870-f5w6fw6q 2514 32 manipulated manipulate VBN cord-006870-f5w6fw6q 2514 33 , , , cord-006870-f5w6fw6q 2514 34 estimated estimate VBN cord-006870-f5w6fw6q 2514 35 blood blood NN cord-006870-f5w6fw6q 2514 36 loss loss NN cord-006870-f5w6fw6q 2514 37 , , , cord-006870-f5w6fw6q 2514 38 post post VB cord-006870-f5w6fw6q 2514 39 op op NN cord-006870-f5w6fw6q 2514 40 blood blood NN cord-006870-f5w6fw6q 2514 41 transfusions transfusion NNS cord-006870-f5w6fw6q 2514 42 , , , cord-006870-f5w6fw6q 2514 43 and and CC cord-006870-f5w6fw6q 2514 44 cause cause NN cord-006870-f5w6fw6q 2514 45 of of IN cord-006870-f5w6fw6q 2514 46 readmission readmission NN cord-006870-f5w6fw6q 2514 47 . . . cord-006870-f5w6fw6q 2515 1 A a DT cord-006870-f5w6fw6q 2515 2 1:1 1:1 CD cord-006870-f5w6fw6q 2515 3 matched match VBN cord-006870-f5w6fw6q 2515 4 control control NN cord-006870-f5w6fw6q 2515 5 group group NN cord-006870-f5w6fw6q 2515 6 based base VBN cord-006870-f5w6fw6q 2515 7 on on IN cord-006870-f5w6fw6q 2515 8 age age NN cord-006870-f5w6fw6q 2515 9 , , , cord-006870-f5w6fw6q 2515 10 BMI bmi NN cord-006870-f5w6fw6q 2515 11 and and CC cord-006870-f5w6fw6q 2515 12 location location NN cord-006870-f5w6fw6q 2515 13 of of IN cord-006870-f5w6fw6q 2515 14 surgery surgery NN cord-006870-f5w6fw6q 2515 15 was be VBD cord-006870-f5w6fw6q 2515 16 identified identify VBN cord-006870-f5w6fw6q 2515 17 . . . cord-006870-f5w6fw6q 2516 1 Thirty thirty CD cord-006870-f5w6fw6q 2516 2 - - HYPH cord-006870-f5w6fw6q 2516 3 two two CD cord-006870-f5w6fw6q 2516 4 patients patient NNS cord-006870-f5w6fw6q 2516 5 required require VBD cord-006870-f5w6fw6q 2516 6 readmission readmission NN cord-006870-f5w6fw6q 2516 7 following follow VBG cord-006870-f5w6fw6q 2516 8 spine spine NN cord-006870-f5w6fw6q 2516 9 surgery surgery NN cord-006870-f5w6fw6q 2516 10 during during IN cord-006870-f5w6fw6q 2516 11 the the DT cord-006870-f5w6fw6q 2516 12 study study NN cord-006870-f5w6fw6q 2516 13 period period NN cord-006870-f5w6fw6q 2516 14 . . . cord-006870-f5w6fw6q 2517 1 There there EX cord-006870-f5w6fw6q 2517 2 was be VBD cord-006870-f5w6fw6q 2517 3 a a DT cord-006870-f5w6fw6q 2517 4 higher high JJR cord-006870-f5w6fw6q 2517 5 prevalence prevalence NN cord-006870-f5w6fw6q 2517 6 of of IN cord-006870-f5w6fw6q 2517 7 preoperative preoperative JJ cord-006870-f5w6fw6q 2517 8 atrial atrial JJ cord-006870-f5w6fw6q 2517 9 fibrillation fibrillation NN cord-006870-f5w6fw6q 2517 10 in in IN cord-006870-f5w6fw6q 2517 11 the the DT cord-006870-f5w6fw6q 2517 12 readmission readmission NN cord-006870-f5w6fw6q 2517 13 group group NN cord-006870-f5w6fw6q 2517 14 ( ( -LRB- cord-006870-f5w6fw6q 2517 15 20 20 CD cord-006870-f5w6fw6q 2517 16 % % NN cord-006870-f5w6fw6q 2517 17 vs. vs. IN cord-006870-f5w6fw6q 2517 18 5 5 CD cord-006870-f5w6fw6q 2517 19 % % NN cord-006870-f5w6fw6q 2517 20 , , , cord-006870-f5w6fw6q 2517 21 p=0.04 p=0.04 NNP cord-006870-f5w6fw6q 2517 22 ) ) -RRB- cord-006870-f5w6fw6q 2517 23 . . . cord-006870-f5w6fw6q 2518 1 EBL EBL NNP cord-006870-f5w6fw6q 2518 2 ( ( -LRB- cord-006870-f5w6fw6q 2518 3 1041 1041 CD cord-006870-f5w6fw6q 2518 4 vs vs IN cord-006870-f5w6fw6q 2518 5 1214 1214 CD cord-006870-f5w6fw6q 2518 6 ml ml NNS cord-006870-f5w6fw6q 2518 7 , , , cord-006870-f5w6fw6q 2518 8 p=0.9 p=0.9 NNP cord-006870-f5w6fw6q 2518 9 ) ) -RRB- cord-006870-f5w6fw6q 2518 10 and and CC cord-006870-f5w6fw6q 2518 11 lowest low JJS cord-006870-f5w6fw6q 2518 12 MAPs map NNS cord-006870-f5w6fw6q 2518 13 ( ( -LRB- cord-006870-f5w6fw6q 2518 14 60 60 CD cord-006870-f5w6fw6q 2518 15 vs vs IN cord-006870-f5w6fw6q 2518 16 59.2 59.2 CD cord-006870-f5w6fw6q 2518 17 mmHg mmHg NNS cord-006870-f5w6fw6q 2518 18 , , , cord-006870-f5w6fw6q 2518 19 p=0.7 p=0.7 NNP cord-006870-f5w6fw6q 2518 20 ) ) -RRB- cord-006870-f5w6fw6q 2518 21 were be VBD cord-006870-f5w6fw6q 2518 22 not not RB cord-006870-f5w6fw6q 2518 23 significantly significantly RB cord-006870-f5w6fw6q 2518 24 different different JJ cord-006870-f5w6fw6q 2518 25 in in IN cord-006870-f5w6fw6q 2518 26 the the DT cord-006870-f5w6fw6q 2518 27 two two CD cord-006870-f5w6fw6q 2518 28 groups group NNS cord-006870-f5w6fw6q 2518 29 . . . cord-006870-f5w6fw6q 2519 1 We -PRON- PRP cord-006870-f5w6fw6q 2519 2 found find VBD cord-006870-f5w6fw6q 2519 3 a a DT cord-006870-f5w6fw6q 2519 4 higher high JJR cord-006870-f5w6fw6q 2519 5 mortality mortality NN cord-006870-f5w6fw6q 2519 6 rate rate NN cord-006870-f5w6fw6q 2519 7 ( ( -LRB- cord-006870-f5w6fw6q 2519 8 22 22 CD cord-006870-f5w6fw6q 2519 9 % % NN cord-006870-f5w6fw6q 2519 10 vs vs IN cord-006870-f5w6fw6q 2519 11 0 0 CD cord-006870-f5w6fw6q 2519 12 % % NN cord-006870-f5w6fw6q 2519 13 , , , cord-006870-f5w6fw6q 2519 14 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 2519 15 ) ) -RRB- cord-006870-f5w6fw6q 2519 16 , , , cord-006870-f5w6fw6q 2519 17 longer long RBR cord-006870-f5w6fw6q 2519 18 ICU ICU NNP cord-006870-f5w6fw6q 2519 19 ( ( -LRB- cord-006870-f5w6fw6q 2519 20 60.7 60.7 CD cord-006870-f5w6fw6q 2519 21 vs vs IN cord-006870-f5w6fw6q 2519 22 39.5 39.5 CD cord-006870-f5w6fw6q 2519 23 hours hour NNS cord-006870-f5w6fw6q 2519 24 , , , cord-006870-f5w6fw6q 2519 25 p=0.06 p=0.06 NNP cord-006870-f5w6fw6q 2519 26 ) ) -RRB- cord-006870-f5w6fw6q 2519 27 and and CC cord-006870-f5w6fw6q 2519 28 hospital hospital NN cord-006870-f5w6fw6q 2519 29 LOS LOS NNP cord-006870-f5w6fw6q 2519 30 ( ( -LRB- cord-006870-f5w6fw6q 2519 31 17.28 17.28 CD cord-006870-f5w6fw6q 2519 32 vs vs IN cord-006870-f5w6fw6q 2519 33 7.87 7.87 CD cord-006870-f5w6fw6q 2519 34 days day NNS cord-006870-f5w6fw6q 2519 35 , , , cord-006870-f5w6fw6q 2519 36 p= p= NN cord-006870-f5w6fw6q 2519 37 0.001 0.001 CD cord-006870-f5w6fw6q 2519 38 ) ) -RRB- cord-006870-f5w6fw6q 2519 39 in in IN cord-006870-f5w6fw6q 2519 40 the the DT cord-006870-f5w6fw6q 2519 41 readmission readmission NN cord-006870-f5w6fw6q 2519 42 group group NN cord-006870-f5w6fw6q 2519 43 . . . cord-006870-f5w6fw6q 2520 1 Respiratory respiratory JJ cord-006870-f5w6fw6q 2520 2 distress distress NN cord-006870-f5w6fw6q 2520 3 ( ( -LRB- cord-006870-f5w6fw6q 2520 4 25 25 CD cord-006870-f5w6fw6q 2520 5 % % NN cord-006870-f5w6fw6q 2520 6 ) ) -RRB- cord-006870-f5w6fw6q 2520 7 was be VBD cord-006870-f5w6fw6q 2520 8 the the DT cord-006870-f5w6fw6q 2520 9 most most RBS cord-006870-f5w6fw6q 2520 10 common common JJ cord-006870-f5w6fw6q 2520 11 reason reason NN cord-006870-f5w6fw6q 2520 12 for for IN cord-006870-f5w6fw6q 2520 13 readmission readmission NN cord-006870-f5w6fw6q 2520 14 followed follow VBN cord-006870-f5w6fw6q 2520 15 by by IN cord-006870-f5w6fw6q 2520 16 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 2520 17 instability instability NN cord-006870-f5w6fw6q 2520 18 ( ( -LRB- cord-006870-f5w6fw6q 2520 19 13 13 CD cord-006870-f5w6fw6q 2520 20 % % NN cord-006870-f5w6fw6q 2520 21 ) ) -RRB- cord-006870-f5w6fw6q 2520 22 . . . cord-006870-f5w6fw6q 2521 1 Discharge discharge NN cord-006870-f5w6fw6q 2521 2 rates rate NNS cord-006870-f5w6fw6q 2521 3 to to IN cord-006870-f5w6fw6q 2521 4 inpatient inpatient JJ cord-006870-f5w6fw6q 2521 5 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 2521 6 and and CC cord-006870-f5w6fw6q 2521 7 nursing nursing NN cord-006870-f5w6fw6q 2521 8 facilities facility NNS cord-006870-f5w6fw6q 2521 9 were be VBD cord-006870-f5w6fw6q 2521 10 similar similar JJ cord-006870-f5w6fw6q 2521 11 for for IN cord-006870-f5w6fw6q 2521 12 both both DT cord-006870-f5w6fw6q 2521 13 groups group NNS cord-006870-f5w6fw6q 2521 14 ; ; : cord-006870-f5w6fw6q 2521 15 however however RB cord-006870-f5w6fw6q 2521 16 42 42 CD cord-006870-f5w6fw6q 2521 17 % % NN cord-006870-f5w6fw6q 2521 18 of of IN cord-006870-f5w6fw6q 2521 19 the the DT cord-006870-f5w6fw6q 2521 20 control control NN cord-006870-f5w6fw6q 2521 21 group group NN cord-006870-f5w6fw6q 2521 22 went go VBD cord-006870-f5w6fw6q 2521 23 directly directly RB cord-006870-f5w6fw6q 2521 24 home home RB cord-006870-f5w6fw6q 2521 25 as as IN cord-006870-f5w6fw6q 2521 26 opposed oppose VBN cord-006870-f5w6fw6q 2521 27 to to IN cord-006870-f5w6fw6q 2521 28 19 19 CD cord-006870-f5w6fw6q 2521 29 % % NN cord-006870-f5w6fw6q 2521 30 of of IN cord-006870-f5w6fw6q 2521 31 the the DT cord-006870-f5w6fw6q 2521 32 readmission readmission NN cord-006870-f5w6fw6q 2521 33 group group NN cord-006870-f5w6fw6q 2521 34 . . . cord-006870-f5w6fw6q 2522 1 Complex complex JJ cord-006870-f5w6fw6q 2522 2 spine spine NN cord-006870-f5w6fw6q 2522 3 patients patient NNS cord-006870-f5w6fw6q 2522 4 who who WP cord-006870-f5w6fw6q 2522 5 experience experience VBP cord-006870-f5w6fw6q 2522 6 ICU ICU NNP cord-006870-f5w6fw6q 2522 7 recidivism recidivism NN cord-006870-f5w6fw6q 2522 8 have have VBP cord-006870-f5w6fw6q 2522 9 a a DT cord-006870-f5w6fw6q 2522 10 longer long JJR cord-006870-f5w6fw6q 2522 11 hospital hospital NN cord-006870-f5w6fw6q 2522 12 stay stay NN cord-006870-f5w6fw6q 2522 13 and and CC cord-006870-f5w6fw6q 2522 14 incidence incidence NN cord-006870-f5w6fw6q 2522 15 of of IN cord-006870-f5w6fw6q 2522 16 death death NN cord-006870-f5w6fw6q 2522 17 within within IN cord-006870-f5w6fw6q 2522 18 5 5 CD cord-006870-f5w6fw6q 2522 19 years year NNS cord-006870-f5w6fw6q 2522 20 of of IN cord-006870-f5w6fw6q 2522 21 their -PRON- PRP$ cord-006870-f5w6fw6q 2522 22 index index NN cord-006870-f5w6fw6q 2522 23 procedure procedure NN cord-006870-f5w6fw6q 2522 24 . . . cord-006870-f5w6fw6q 2523 1 They -PRON- PRP cord-006870-f5w6fw6q 2523 2 are be VBP cord-006870-f5w6fw6q 2523 3 less less RBR cord-006870-f5w6fw6q 2523 4 likely likely JJ cord-006870-f5w6fw6q 2523 5 to to TO cord-006870-f5w6fw6q 2523 6 be be VB cord-006870-f5w6fw6q 2523 7 discharged discharge VBN cord-006870-f5w6fw6q 2523 8 home home RB cord-006870-f5w6fw6q 2523 9 . . . cord-006870-f5w6fw6q 2524 1 Preoperative Preoperative NNP cord-006870-f5w6fw6q 2524 2 a a DT cord-006870-f5w6fw6q 2524 3 - - HYPH cord-006870-f5w6fw6q 2524 4 fib fib NN cord-006870-f5w6fw6q 2524 5 correlates correlate VBZ cord-006870-f5w6fw6q 2524 6 with with IN cord-006870-f5w6fw6q 2524 7 increased increase VBN cord-006870-f5w6fw6q 2524 8 incidence incidence NN cord-006870-f5w6fw6q 2524 9 of of IN cord-006870-f5w6fw6q 2524 10 readmission readmission NN cord-006870-f5w6fw6q 2524 11 to to IN cord-006870-f5w6fw6q 2524 12 ICU ICU NNP cord-006870-f5w6fw6q 2524 13 post post RB cord-006870-f5w6fw6q 2524 14 - - JJ cord-006870-f5w6fw6q 2524 15 operatively operatively RB cord-006870-f5w6fw6q 2524 16 . . . cord-006870-f5w6fw6q 2525 1 Further further JJ cord-006870-f5w6fw6q 2525 2 studies study NNS cord-006870-f5w6fw6q 2525 3 are be VBP cord-006870-f5w6fw6q 2525 4 needed need VBN cord-006870-f5w6fw6q 2525 5 looking look VBG cord-006870-f5w6fw6q 2525 6 at at IN cord-006870-f5w6fw6q 2525 7 post post JJ cord-006870-f5w6fw6q 2525 8 operative operative JJ cord-006870-f5w6fw6q 2525 9 fluid fluid NN cord-006870-f5w6fw6q 2525 10 and and CC cord-006870-f5w6fw6q 2525 11 pain pain NN cord-006870-f5w6fw6q 2525 12 management management NN cord-006870-f5w6fw6q 2525 13 . . . cord-006870-f5w6fw6q 2526 1 To to TO cord-006870-f5w6fw6q 2526 2 demonstrate demonstrate VB cord-006870-f5w6fw6q 2526 3 the the DT cord-006870-f5w6fw6q 2526 4 feasibility feasibility NN cord-006870-f5w6fw6q 2526 5 of of IN cord-006870-f5w6fw6q 2526 6 exenatide exenatide JJ cord-006870-f5w6fw6q 2526 7 infusion infusion NN cord-006870-f5w6fw6q 2526 8 for for IN cord-006870-f5w6fw6q 2526 9 hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 2526 10 following follow VBG cord-006870-f5w6fw6q 2526 11 acute acute JJ cord-006870-f5w6fw6q 2526 12 brain brain NN cord-006870-f5w6fw6q 2526 13 injury injury NN cord-006870-f5w6fw6q 2526 14 . . . cord-006870-f5w6fw6q 2527 1 Adult adult NN cord-006870-f5w6fw6q 2527 2 patients patient NNS cord-006870-f5w6fw6q 2527 3 with with IN cord-006870-f5w6fw6q 2527 4 acute acute JJ cord-006870-f5w6fw6q 2527 5 brain brain NN cord-006870-f5w6fw6q 2527 6 injury injury NN cord-006870-f5w6fw6q 2527 7 and and CC cord-006870-f5w6fw6q 2527 8 having have VBG cord-006870-f5w6fw6q 2527 9 two two CD cord-006870-f5w6fw6q 2527 10 blood blood NN cord-006870-f5w6fw6q 2527 11 glucose glucose NN cord-006870-f5w6fw6q 2527 12 concentrations concentration NNS cord-006870-f5w6fw6q 2527 13 > > XX cord-006870-f5w6fw6q 2528 1 150 150 CD cord-006870-f5w6fw6q 2528 2 mg mg NNP cord-006870-f5w6fw6q 2528 3 / / SYM cord-006870-f5w6fw6q 2528 4 dL dl NN cord-006870-f5w6fw6q 2528 5 and and CC cord-006870-f5w6fw6q 2528 6 was be VBD cord-006870-f5w6fw6q 2528 7 administered administer VBN cord-006870-f5w6fw6q 2528 8 within within IN cord-006870-f5w6fw6q 2528 9 48 48 CD cord-006870-f5w6fw6q 2528 10 hours hour NNS cord-006870-f5w6fw6q 2528 11 of of IN cord-006870-f5w6fw6q 2528 12 admission admission NN cord-006870-f5w6fw6q 2528 13 and and CC cord-006870-f5w6fw6q 2528 14 continued continue VBN cord-006870-f5w6fw6q 2528 15 per per IN cord-006870-f5w6fw6q 2528 16 protocol protocol NN cord-006870-f5w6fw6q 2528 17 for for IN cord-006870-f5w6fw6q 2528 18 a a DT cord-006870-f5w6fw6q 2528 19 maximum maximum JJ cord-006870-f5w6fw6q 2528 20 duration duration NN cord-006870-f5w6fw6q 2528 21 of of IN cord-006870-f5w6fw6q 2528 22 48 48 CD cord-006870-f5w6fw6q 2528 23 hours hour NNS cord-006870-f5w6fw6q 2528 24 . . . cord-006870-f5w6fw6q 2529 1 The the DT cord-006870-f5w6fw6q 2529 2 primary primary JJ cord-006870-f5w6fw6q 2529 3 endpoint endpoint NN cord-006870-f5w6fw6q 2529 4 was be VBD cord-006870-f5w6fw6q 2529 5 feasibility feasibility NN cord-006870-f5w6fw6q 2529 6 ( ( -LRB- cord-006870-f5w6fw6q 2529 7 < < NNP cord-006870-f5w6fw6q 2529 8 25 25 CD cord-006870-f5w6fw6q 2529 9 % % NN cord-006870-f5w6fw6q 2529 10 of of IN cord-006870-f5w6fw6q 2529 11 subjects subject NNS cord-006870-f5w6fw6q 2529 12 experiencing experience VBG cord-006870-f5w6fw6q 2529 13 severe severe JJ cord-006870-f5w6fw6q 2529 14 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 2529 15 ( ( -LRB- cord-006870-f5w6fw6q 2529 16 < < XX cord-006870-f5w6fw6q 2529 17 40 40 CD cord-006870-f5w6fw6q 2530 1 -180 -180 NNP cord-006870-f5w6fw6q 2530 2 mg mg NNP cord-006870-f5w6fw6q 2530 3 / / SYM cord-006870-f5w6fw6q 2530 4 dL dl NN cord-006870-f5w6fw6q 2530 5 ) ) -RRB- cord-006870-f5w6fw6q 2530 6 . . . cord-006870-f5w6fw6q 2531 1 Descriptive descriptive JJ cord-006870-f5w6fw6q 2531 2 endpoints endpoint NNS cord-006870-f5w6fw6q 2531 3 were be VBD cord-006870-f5w6fw6q 2531 4 also also RB cord-006870-f5w6fw6q 2531 5 collected collect VBN cord-006870-f5w6fw6q 2531 6 . . . cord-006870-f5w6fw6q 2532 1 Data Data NNP cord-006870-f5w6fw6q 2532 2 is be VBZ cord-006870-f5w6fw6q 2532 3 presented present VBN cord-006870-f5w6fw6q 2532 4 as as IN cord-006870-f5w6fw6q 2532 5 medians median NNS cord-006870-f5w6fw6q 2532 6 [ [ -LRB- cord-006870-f5w6fw6q 2532 7 interquartile interquartile JJ cord-006870-f5w6fw6q 2532 8 range range NN cord-006870-f5w6fw6q 2532 9 ] ] -RRB- cord-006870-f5w6fw6q 2532 10 or or CC cord-006870-f5w6fw6q 2532 11 percentages percentage NNS cord-006870-f5w6fw6q 2532 12 . . . cord-006870-f5w6fw6q 2533 1 A a DT cord-006870-f5w6fw6q 2533 2 total total NN cord-006870-f5w6fw6q 2533 3 of of IN cord-006870-f5w6fw6q 2533 4 eight eight CD cord-006870-f5w6fw6q 2533 5 patients patient NNS cord-006870-f5w6fw6q 2533 6 received receive VBN cord-006870-f5w6fw6q 2533 7 exenatide exenatide NN cord-006870-f5w6fw6q 2533 8 ( ( -LRB- cord-006870-f5w6fw6q 2533 9 age age NN cord-006870-f5w6fw6q 2533 10 64.0 64.0 CD cord-006870-f5w6fw6q 2533 11 years year NNS cord-006870-f5w6fw6q 2533 12 [ [ -LRB- cord-006870-f5w6fw6q 2533 13 58.8 58.8 CD cord-006870-f5w6fw6q 2533 14 , , , cord-006870-f5w6fw6q 2533 15 67.8 67.8 CD cord-006870-f5w6fw6q 2533 16 ] ] -RRB- cord-006870-f5w6fw6q 2533 17 , , , cord-006870-f5w6fw6q 2533 18 87.5 87.5 CD cord-006870-f5w6fw6q 2533 19 % % NN cord-006870-f5w6fw6q 2533 20 male male NN cord-006870-f5w6fw6q 2533 21 , , , cord-006870-f5w6fw6q 2533 22 50.0 50.0 CD cord-006870-f5w6fw6q 2533 23 % % NN cord-006870-f5w6fw6q 2533 24 Caucasian caucasian JJ cord-006870-f5w6fw6q 2533 25 , , , cord-006870-f5w6fw6q 2533 26 50.0 50.0 CD cord-006870-f5w6fw6q 2533 27 % % NN cord-006870-f5w6fw6q 2533 28 history history NN cord-006870-f5w6fw6q 2533 29 of of IN cord-006870-f5w6fw6q 2533 30 diabetes diabetes NN cord-006870-f5w6fw6q 2533 31 , , , cord-006870-f5w6fw6q 2533 32 A1c A1c NNP cord-006870-f5w6fw6q 2533 33 6.5 6.5 CD cord-006870-f5w6fw6q 2533 34 % % NN cord-006870-f5w6fw6q 2533 35 [ [ -LRB- cord-006870-f5w6fw6q 2533 36 5.5,7.3 5.5,7.3 CD cord-006870-f5w6fw6q 2533 37 ] ] -RRB- cord-006870-f5w6fw6q 2533 38 ) ) -RRB- cord-006870-f5w6fw6q 2533 39 . . . cord-006870-f5w6fw6q 2534 1 Admitting admit VBG cord-006870-f5w6fw6q 2534 2 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2534 3 were be VBD cord-006870-f5w6fw6q 2534 4 intracerebral intracerebral JJ cord-006870-f5w6fw6q 2534 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2534 6 ( ( -LRB- cord-006870-f5w6fw6q 2534 7 n=3 n=3 NN cord-006870-f5w6fw6q 2534 8 ) ) -RRB- cord-006870-f5w6fw6q 2534 9 , , , cord-006870-f5w6fw6q 2534 10 acute acute JJ cord-006870-f5w6fw6q 2534 11 ischemic ischemic JJ cord-006870-f5w6fw6q 2534 12 stroke stroke NN cord-006870-f5w6fw6q 2534 13 ( ( -LRB- cord-006870-f5w6fw6q 2534 14 n=3 n=3 NN cord-006870-f5w6fw6q 2534 15 ) ) -RRB- cord-006870-f5w6fw6q 2534 16 , , , cord-006870-f5w6fw6q 2534 17 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2534 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2534 19 ( ( -LRB- cord-006870-f5w6fw6q 2534 20 n=1 n=1 CD cord-006870-f5w6fw6q 2534 21 ) ) -RRB- cord-006870-f5w6fw6q 2534 22 , , , cord-006870-f5w6fw6q 2534 23 and and CC cord-006870-f5w6fw6q 2534 24 subdural subdural JJ cord-006870-f5w6fw6q 2534 25 hematoma hematoma NN cord-006870-f5w6fw6q 2534 26 ( ( -LRB- cord-006870-f5w6fw6q 2534 27 n=1 n=1 FW cord-006870-f5w6fw6q 2534 28 ) ) -RRB- cord-006870-f5w6fw6q 2534 29 . . . cord-006870-f5w6fw6q 2535 1 Glascow Glascow NNP cord-006870-f5w6fw6q 2535 2 coma coma NN cord-006870-f5w6fw6q 2535 3 score score NN cord-006870-f5w6fw6q 2535 4 was be VBD cord-006870-f5w6fw6q 2535 5 10.5 10.5 CD cord-006870-f5w6fw6q 2535 6 [ [ -LRB- cord-006870-f5w6fw6q 2535 7 7.0 7.0 CD cord-006870-f5w6fw6q 2535 8 , , , cord-006870-f5w6fw6q 2535 9 14.0 14.0 CD cord-006870-f5w6fw6q 2535 10 ] ] -RRB- cord-006870-f5w6fw6q 2535 11 and and CC cord-006870-f5w6fw6q 2536 1 Sequential Sequential NNP cord-006870-f5w6fw6q 2536 2 Organ Organ NNP cord-006870-f5w6fw6q 2536 3 Failure Failure NNP cord-006870-f5w6fw6q 2536 4 Assessment Assessment NNP cord-006870-f5w6fw6q 2536 5 was be VBD cord-006870-f5w6fw6q 2536 6 2.0 2.0 CD cord-006870-f5w6fw6q 2536 7 [ [ -LRB- cord-006870-f5w6fw6q 2536 8 1.0 1.0 CD cord-006870-f5w6fw6q 2536 9 , , , cord-006870-f5w6fw6q 2536 10 4.0 4.0 CD cord-006870-f5w6fw6q 2536 11 ] ] -RRB- cord-006870-f5w6fw6q 2536 12 . . . cord-006870-f5w6fw6q 2537 1 Based base VBN cord-006870-f5w6fw6q 2537 2 upon upon IN cord-006870-f5w6fw6q 2537 3 predefined predefined JJ cord-006870-f5w6fw6q 2537 4 criteria criterion NNS cord-006870-f5w6fw6q 2537 5 , , , cord-006870-f5w6fw6q 2537 6 feasibility feasibility NN cord-006870-f5w6fw6q 2537 7 was be VBD cord-006870-f5w6fw6q 2537 8 met meet VBN cord-006870-f5w6fw6q 2537 9 with with IN cord-006870-f5w6fw6q 2537 10 0 0 CD cord-006870-f5w6fw6q 2537 11 % % NN cord-006870-f5w6fw6q 2537 12 of of IN cord-006870-f5w6fw6q 2537 13 subjects subject NNS cord-006870-f5w6fw6q 2537 14 experiencing experience VBG cord-006870-f5w6fw6q 2537 15 severe severe JJ cord-006870-f5w6fw6q 2537 16 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 2537 17 , , , cord-006870-f5w6fw6q 2537 18 87.5 87.5 CD cord-006870-f5w6fw6q 2537 19 % % NN cord-006870-f5w6fw6q 2537 20 achieving achieve VBG cord-006870-f5w6fw6q 2537 21 the the DT cord-006870-f5w6fw6q 2537 22 blood blood NN cord-006870-f5w6fw6q 2537 23 glucose glucose NN cord-006870-f5w6fw6q 2537 24 goal goal NN cord-006870-f5w6fw6q 2537 25 , , , cord-006870-f5w6fw6q 2537 26 and and CC cord-006870-f5w6fw6q 2537 27 0 0 CD cord-006870-f5w6fw6q 2537 28 % % NN cord-006870-f5w6fw6q 2537 29 experiencing experience VBG cord-006870-f5w6fw6q 2537 30 nausea nausea NN cord-006870-f5w6fw6q 2537 31 requiring require VBG cord-006870-f5w6fw6q 2537 32 discontinuation discontinuation NN cord-006870-f5w6fw6q 2537 33 . . . cord-006870-f5w6fw6q 2538 1 Blood blood NN cord-006870-f5w6fw6q 2538 2 glucose glucose NN cord-006870-f5w6fw6q 2538 3 was be VBD cord-006870-f5w6fw6q 2538 4 controlled control VBN cord-006870-f5w6fw6q 2538 5 during during IN cord-006870-f5w6fw6q 2538 6 the the DT cord-006870-f5w6fw6q 2538 7 48-hour 48-hour CD cord-006870-f5w6fw6q 2538 8 exenatide exenatide NN cord-006870-f5w6fw6q 2538 9 infusion infusion NN cord-006870-f5w6fw6q 2538 10 ( ( -LRB- cord-006870-f5w6fw6q 2538 11 _SP cord-006870-f5w6fw6q 2538 12 Intravenous Intravenous NNP cord-006870-f5w6fw6q 2538 13 exenatide exenatide NN cord-006870-f5w6fw6q 2538 14 infusion infusion NN cord-006870-f5w6fw6q 2538 15 is be VBZ cord-006870-f5w6fw6q 2538 16 feasible feasible JJ cord-006870-f5w6fw6q 2538 17 for for IN cord-006870-f5w6fw6q 2538 18 the the DT cord-006870-f5w6fw6q 2538 19 treatment treatment NN cord-006870-f5w6fw6q 2538 20 of of IN cord-006870-f5w6fw6q 2538 21 hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 2538 22 following follow VBG cord-006870-f5w6fw6q 2538 23 acute acute JJ cord-006870-f5w6fw6q 2538 24 brain brain NN cord-006870-f5w6fw6q 2538 25 injury injury NN cord-006870-f5w6fw6q 2538 26 . . . cord-006870-f5w6fw6q 2539 1 Extubation extubation NN cord-006870-f5w6fw6q 2539 2 failure failure NN cord-006870-f5w6fw6q 2539 3 remains remain VBZ cord-006870-f5w6fw6q 2539 4 a a DT cord-006870-f5w6fw6q 2539 5 common common JJ cord-006870-f5w6fw6q 2539 6 complication complication NN cord-006870-f5w6fw6q 2539 7 in in IN cord-006870-f5w6fw6q 2539 8 critical critical JJ cord-006870-f5w6fw6q 2539 9 care care NN cord-006870-f5w6fw6q 2539 10 patients patient NNS cord-006870-f5w6fw6q 2539 11 , , , cord-006870-f5w6fw6q 2539 12 and and CC cord-006870-f5w6fw6q 2539 13 is be VBZ cord-006870-f5w6fw6q 2539 14 associated associate VBN cord-006870-f5w6fw6q 2539 15 with with IN cord-006870-f5w6fw6q 2539 16 increased increase VBN cord-006870-f5w6fw6q 2539 17 intensive intensive JJ cord-006870-f5w6fw6q 2539 18 care care NN cord-006870-f5w6fw6q 2539 19 unit unit NN cord-006870-f5w6fw6q 2539 20 and and CC cord-006870-f5w6fw6q 2539 21 hospital hospital NN cord-006870-f5w6fw6q 2539 22 length length NN cord-006870-f5w6fw6q 2539 23 of of IN cord-006870-f5w6fw6q 2539 24 stays stay NNS cord-006870-f5w6fw6q 2539 25 , , , cord-006870-f5w6fw6q 2539 26 hospital hospital NN cord-006870-f5w6fw6q 2539 27 costs cost NNS cord-006870-f5w6fw6q 2539 28 , , , cord-006870-f5w6fw6q 2539 29 morbidity morbidity NN cord-006870-f5w6fw6q 2539 30 and and CC cord-006870-f5w6fw6q 2539 31 mortality mortality NN cord-006870-f5w6fw6q 2539 32 . . . cord-006870-f5w6fw6q 2540 1 The the DT cord-006870-f5w6fw6q 2540 2 most most RBS cord-006870-f5w6fw6q 2540 3 common common JJ cord-006870-f5w6fw6q 2540 4 cause cause NN cord-006870-f5w6fw6q 2540 5 of of IN cord-006870-f5w6fw6q 2540 6 reintubation reintubation NN cord-006870-f5w6fw6q 2540 7 is be VBZ cord-006870-f5w6fw6q 2540 8 laryngeal laryngeal NN cord-006870-f5w6fw6q 2540 9 edema edema NN cord-006870-f5w6fw6q 2540 10 , , , cord-006870-f5w6fw6q 2540 11 often often RB cord-006870-f5w6fw6q 2540 12 identified identify VBN cord-006870-f5w6fw6q 2540 13 by by IN cord-006870-f5w6fw6q 2540 14 the the DT cord-006870-f5w6fw6q 2540 15 presence presence NN cord-006870-f5w6fw6q 2540 16 of of IN cord-006870-f5w6fw6q 2540 17 a a DT cord-006870-f5w6fw6q 2540 18 high high JJ cord-006870-f5w6fw6q 2540 19 pitched pitch VBN cord-006870-f5w6fw6q 2540 20 inspiratory inspiratory JJ cord-006870-f5w6fw6q 2540 21 whistling whistle VBG cord-006870-f5w6fw6q 2540 22 sound sound NN cord-006870-f5w6fw6q 2540 23 known know VBN cord-006870-f5w6fw6q 2540 24 as as IN cord-006870-f5w6fw6q 2540 25 post post NN cord-006870-f5w6fw6q 2540 26 - - JJ cord-006870-f5w6fw6q 2540 27 extubation extubation JJ cord-006870-f5w6fw6q 2540 28 stridor stridor NNP cord-006870-f5w6fw6q 2540 29 ( ( -LRB- cord-006870-f5w6fw6q 2540 30 PES PES NNP cord-006870-f5w6fw6q 2540 31 ) ) -RRB- cord-006870-f5w6fw6q 2540 32 . . . cord-006870-f5w6fw6q 2541 1 Providers provider NNS cord-006870-f5w6fw6q 2541 2 in in IN cord-006870-f5w6fw6q 2541 3 the the DT cord-006870-f5w6fw6q 2541 4 neurocritical neurocritical NNP cord-006870-f5w6fw6q 2541 5 care care NN cord-006870-f5w6fw6q 2541 6 unit unit NN cord-006870-f5w6fw6q 2541 7 ( ( -LRB- cord-006870-f5w6fw6q 2541 8 NCCU NCCU NNP cord-006870-f5w6fw6q 2541 9 ) ) -RRB- cord-006870-f5w6fw6q 2541 10 at at IN cord-006870-f5w6fw6q 2541 11 a a DT cord-006870-f5w6fw6q 2541 12 large large JJ cord-006870-f5w6fw6q 2541 13 urban urban JJ cord-006870-f5w6fw6q 2541 14 academic academic JJ cord-006870-f5w6fw6q 2541 15 medical medical JJ cord-006870-f5w6fw6q 2541 16 center center NN cord-006870-f5w6fw6q 2541 17 noted note VBD cord-006870-f5w6fw6q 2541 18 higher higher RBR cord-006870-f5w6fw6q 2541 19 than than IN cord-006870-f5w6fw6q 2541 20 normal normal JJ cord-006870-f5w6fw6q 2541 21 rates rate NNS cord-006870-f5w6fw6q 2541 22 of of IN cord-006870-f5w6fw6q 2541 23 PES PES NNP cord-006870-f5w6fw6q 2541 24 . . . cord-006870-f5w6fw6q 2542 1 To to TO cord-006870-f5w6fw6q 2542 2 reduce reduce VB cord-006870-f5w6fw6q 2542 3 the the DT cord-006870-f5w6fw6q 2542 4 rates rate NNS cord-006870-f5w6fw6q 2542 5 of of IN cord-006870-f5w6fw6q 2542 6 PES PES NNP cord-006870-f5w6fw6q 2542 7 and and CC cord-006870-f5w6fw6q 2542 8 reintubation reintubation NN cord-006870-f5w6fw6q 2542 9 without without IN cord-006870-f5w6fw6q 2542 10 delaying delay VBG cord-006870-f5w6fw6q 2542 11 extubation extubation NN cord-006870-f5w6fw6q 2542 12 , , , cord-006870-f5w6fw6q 2542 13 a a DT cord-006870-f5w6fw6q 2542 14 clinical clinical JJ cord-006870-f5w6fw6q 2542 15 pathway pathway NN cord-006870-f5w6fw6q 2542 16 was be VBD cord-006870-f5w6fw6q 2542 17 created create VBN cord-006870-f5w6fw6q 2542 18 by by IN cord-006870-f5w6fw6q 2542 19 an an DT cord-006870-f5w6fw6q 2542 20 interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 2542 21 team team NN cord-006870-f5w6fw6q 2542 22 . . . cord-006870-f5w6fw6q 2543 1 The the DT cord-006870-f5w6fw6q 2543 2 purpose purpose NN cord-006870-f5w6fw6q 2543 3 of of IN cord-006870-f5w6fw6q 2543 4 the the DT cord-006870-f5w6fw6q 2543 5 pathway pathway NN cord-006870-f5w6fw6q 2543 6 was be VBD cord-006870-f5w6fw6q 2543 7 to to TO cord-006870-f5w6fw6q 2543 8 aid aid VB cord-006870-f5w6fw6q 2543 9 in in IN cord-006870-f5w6fw6q 2543 10 the the DT cord-006870-f5w6fw6q 2543 11 identification identification NN cord-006870-f5w6fw6q 2543 12 of of IN cord-006870-f5w6fw6q 2543 13 patients patient NNS cord-006870-f5w6fw6q 2543 14 expected expect VBN cord-006870-f5w6fw6q 2543 15 to to TO cord-006870-f5w6fw6q 2543 16 develop develop VB cord-006870-f5w6fw6q 2543 17 PES PES NNP cord-006870-f5w6fw6q 2543 18 and and CC cord-006870-f5w6fw6q 2543 19 guide guide VB cord-006870-f5w6fw6q 2543 20 prophylactic prophylactic JJ cord-006870-f5w6fw6q 2543 21 treatment treatment NN cord-006870-f5w6fw6q 2543 22 . . . cord-006870-f5w6fw6q 2544 1 Prior prior RB cord-006870-f5w6fw6q 2544 2 to to IN cord-006870-f5w6fw6q 2544 3 project project NN cord-006870-f5w6fw6q 2544 4 implementation implementation NN cord-006870-f5w6fw6q 2544 5 , , , cord-006870-f5w6fw6q 2544 6 all all DT cord-006870-f5w6fw6q 2544 7 providers provider NNS cord-006870-f5w6fw6q 2544 8 in in IN cord-006870-f5w6fw6q 2544 9 the the DT cord-006870-f5w6fw6q 2544 10 NCCU NCCU NNP cord-006870-f5w6fw6q 2544 11 completed complete VBD cord-006870-f5w6fw6q 2544 12 hands hand NNS cord-006870-f5w6fw6q 2544 13 on on IN cord-006870-f5w6fw6q 2544 14 training training NN cord-006870-f5w6fw6q 2544 15 with with IN cord-006870-f5w6fw6q 2544 16 practice practice NN cord-006870-f5w6fw6q 2544 17 in in IN cord-006870-f5w6fw6q 2544 18 completing complete VBG cord-006870-f5w6fw6q 2544 19 the the DT cord-006870-f5w6fw6q 2544 20 pathway pathway NN cord-006870-f5w6fw6q 2544 21 in in IN cord-006870-f5w6fw6q 2544 22 the the DT cord-006870-f5w6fw6q 2544 23 form form NN cord-006870-f5w6fw6q 2544 24 of of IN cord-006870-f5w6fw6q 2544 25 a a DT cord-006870-f5w6fw6q 2544 26 checklist checklist NN cord-006870-f5w6fw6q 2544 27 . . . cord-006870-f5w6fw6q 2545 1 During during IN cord-006870-f5w6fw6q 2545 2 the the DT cord-006870-f5w6fw6q 2545 3 12 12 CD cord-006870-f5w6fw6q 2545 4 week week NN cord-006870-f5w6fw6q 2545 5 implementation implementation NN cord-006870-f5w6fw6q 2545 6 phase phase NN cord-006870-f5w6fw6q 2545 7 , , , cord-006870-f5w6fw6q 2545 8 checklists checklist NNS cord-006870-f5w6fw6q 2545 9 were be VBD cord-006870-f5w6fw6q 2545 10 completed complete VBN cord-006870-f5w6fw6q 2545 11 on on IN cord-006870-f5w6fw6q 2545 12 all all DT cord-006870-f5w6fw6q 2545 13 intubated intubate VBN cord-006870-f5w6fw6q 2545 14 patients patient NNS cord-006870-f5w6fw6q 2545 15 daily daily RB cord-006870-f5w6fw6q 2545 16 during during IN cord-006870-f5w6fw6q 2545 17 rounds round NNS cord-006870-f5w6fw6q 2545 18 . . . cord-006870-f5w6fw6q 2546 1 During during IN cord-006870-f5w6fw6q 2546 2 the the DT cord-006870-f5w6fw6q 2546 3 12 12 CD cord-006870-f5w6fw6q 2546 4 week week NN cord-006870-f5w6fw6q 2546 5 trial trial NN cord-006870-f5w6fw6q 2546 6 , , , cord-006870-f5w6fw6q 2546 7 there there EX cord-006870-f5w6fw6q 2546 8 were be VBD cord-006870-f5w6fw6q 2546 9 a a DT cord-006870-f5w6fw6q 2546 10 total total NN cord-006870-f5w6fw6q 2546 11 of of IN cord-006870-f5w6fw6q 2546 12 606 606 CD cord-006870-f5w6fw6q 2546 13 ventilator ventilator NN cord-006870-f5w6fw6q 2546 14 days day NNS cord-006870-f5w6fw6q 2546 15 . . . cord-006870-f5w6fw6q 2547 1 There there EX cord-006870-f5w6fw6q 2547 2 were be VBD cord-006870-f5w6fw6q 2547 3 531 531 CD cord-006870-f5w6fw6q 2547 4 completed complete VBN cord-006870-f5w6fw6q 2547 5 checklists checklist NNS cord-006870-f5w6fw6q 2547 6 , , , cord-006870-f5w6fw6q 2547 7 yielding yield VBG cord-006870-f5w6fw6q 2547 8 an an DT cord-006870-f5w6fw6q 2547 9 87.62 87.62 CD cord-006870-f5w6fw6q 2547 10 % % NN cord-006870-f5w6fw6q 2547 11 compliance compliance NN cord-006870-f5w6fw6q 2547 12 rate rate NN cord-006870-f5w6fw6q 2547 13 for for IN cord-006870-f5w6fw6q 2547 14 utilization utilization NN cord-006870-f5w6fw6q 2547 15 of of IN cord-006870-f5w6fw6q 2547 16 the the DT cord-006870-f5w6fw6q 2547 17 clinical clinical JJ cord-006870-f5w6fw6q 2547 18 pathway pathway NN cord-006870-f5w6fw6q 2547 19 . . . cord-006870-f5w6fw6q 2548 1 Of of IN cord-006870-f5w6fw6q 2548 2 the the DT cord-006870-f5w6fw6q 2548 3 56 56 CD cord-006870-f5w6fw6q 2548 4 patients patient NNS cord-006870-f5w6fw6q 2548 5 who who WP cord-006870-f5w6fw6q 2548 6 were be VBD cord-006870-f5w6fw6q 2548 7 extubated extubate VBN cord-006870-f5w6fw6q 2548 8 during during IN cord-006870-f5w6fw6q 2548 9 the the DT cord-006870-f5w6fw6q 2548 10 trial trial NN cord-006870-f5w6fw6q 2548 11 , , , cord-006870-f5w6fw6q 2548 12 54 54 CD cord-006870-f5w6fw6q 2548 13 had have VBD cord-006870-f5w6fw6q 2548 14 a a DT cord-006870-f5w6fw6q 2548 15 checklist checklist NN cord-006870-f5w6fw6q 2548 16 completed complete VBN cord-006870-f5w6fw6q 2548 17 , , , cord-006870-f5w6fw6q 2548 18 generating generate VBG cord-006870-f5w6fw6q 2548 19 96.43 96.43 CD cord-006870-f5w6fw6q 2548 20 % % NN cord-006870-f5w6fw6q 2548 21 compliance compliance NN cord-006870-f5w6fw6q 2548 22 on on IN cord-006870-f5w6fw6q 2548 23 the the DT cord-006870-f5w6fw6q 2548 24 day day NN cord-006870-f5w6fw6q 2548 25 of of IN cord-006870-f5w6fw6q 2548 26 extubation extubation NN cord-006870-f5w6fw6q 2548 27 . . . cord-006870-f5w6fw6q 2549 1 A a DT cord-006870-f5w6fw6q 2549 2 chi chi JJ cord-006870-f5w6fw6q 2549 3 - - JJ cord-006870-f5w6fw6q 2549 4 square square JJ cord-006870-f5w6fw6q 2549 5 analysis analysis NN cord-006870-f5w6fw6q 2549 6 was be VBD cord-006870-f5w6fw6q 2549 7 performed perform VBN cord-006870-f5w6fw6q 2549 8 to to TO cord-006870-f5w6fw6q 2549 9 evaluate evaluate VB cord-006870-f5w6fw6q 2549 10 outcomes outcome NNS cord-006870-f5w6fw6q 2549 11 following follow VBG cord-006870-f5w6fw6q 2549 12 all all DT cord-006870-f5w6fw6q 2549 13 non non JJ cord-006870-f5w6fw6q 2549 14 - - JJ cord-006870-f5w6fw6q 2549 15 palliative palliative JJ cord-006870-f5w6fw6q 2549 16 extubations extubation NNS cord-006870-f5w6fw6q 2549 17 during during IN cord-006870-f5w6fw6q 2549 18 the the DT cord-006870-f5w6fw6q 2549 19 12 12 CD cord-006870-f5w6fw6q 2549 20 week week NN cord-006870-f5w6fw6q 2549 21 pre pre JJ cord-006870-f5w6fw6q 2549 22 - - NN cord-006870-f5w6fw6q 2549 23 implementation implementation JJ cord-006870-f5w6fw6q 2549 24 ( ( -LRB- cord-006870-f5w6fw6q 2549 25 n n NN cord-006870-f5w6fw6q 2549 26 = = SYM cord-006870-f5w6fw6q 2549 27 43 43 CD cord-006870-f5w6fw6q 2549 28 ) ) -RRB- cord-006870-f5w6fw6q 2549 29 and and CC cord-006870-f5w6fw6q 2549 30 post post NN cord-006870-f5w6fw6q 2549 31 - - NN cord-006870-f5w6fw6q 2549 32 implementation implementation JJ cord-006870-f5w6fw6q 2549 33 ( ( -LRB- cord-006870-f5w6fw6q 2549 34 n n NN cord-006870-f5w6fw6q 2549 35 = = SYM cord-006870-f5w6fw6q 2549 36 56 56 CD cord-006870-f5w6fw6q 2549 37 ) ) -RRB- cord-006870-f5w6fw6q 2549 38 periods period NNS cord-006870-f5w6fw6q 2549 39 . . . cord-006870-f5w6fw6q 2550 1 Implementation implementation NN cord-006870-f5w6fw6q 2550 2 of of IN cord-006870-f5w6fw6q 2550 3 the the DT cord-006870-f5w6fw6q 2550 4 pathway pathway NN cord-006870-f5w6fw6q 2550 5 was be VBD cord-006870-f5w6fw6q 2550 6 associated associate VBN cord-006870-f5w6fw6q 2550 7 with with IN cord-006870-f5w6fw6q 2550 8 a a DT cord-006870-f5w6fw6q 2550 9 statistically statistically RB cord-006870-f5w6fw6q 2550 10 significant significant JJ cord-006870-f5w6fw6q 2550 11 reduction reduction NN cord-006870-f5w6fw6q 2550 12 in in IN cord-006870-f5w6fw6q 2550 13 rates rate NNS cord-006870-f5w6fw6q 2550 14 of of IN cord-006870-f5w6fw6q 2550 15 PES PES NNP cord-006870-f5w6fw6q 2550 16 ( ( -LRB- cord-006870-f5w6fw6q 2550 17 1 1 CD cord-006870-f5w6fw6q 2550 18 , , , cord-006870-f5w6fw6q 2550 19 N n CD cord-006870-f5w6fw6q 2550 20 = = SYM cord-006870-f5w6fw6q 2550 21 99 99 CD cord-006870-f5w6fw6q 2550 22 ) ) -RRB- cord-006870-f5w6fw6q 2550 23 = = NFP cord-006870-f5w6fw6q 2551 1 6.16 6.16 CD cord-006870-f5w6fw6q 2551 2 , , , cord-006870-f5w6fw6q 2551 3 p<0.02 p<0.02 UH cord-006870-f5w6fw6q 2551 4 , , , cord-006870-f5w6fw6q 2551 5 reintubation reintubation NN cord-006870-f5w6fw6q 2551 6 ( ( -LRB- cord-006870-f5w6fw6q 2551 7 1 1 CD cord-006870-f5w6fw6q 2551 8 , , , cord-006870-f5w6fw6q 2551 9 N n CD cord-006870-f5w6fw6q 2551 10 = = SYM cord-006870-f5w6fw6q 2551 11 99 99 CD cord-006870-f5w6fw6q 2551 12 ) ) -RRB- cord-006870-f5w6fw6q 2551 13 = = NFP cord-006870-f5w6fw6q 2552 1 5.54 5.54 CD cord-006870-f5w6fw6q 2552 2 , , , cord-006870-f5w6fw6q 2552 3 p<0.02 p<0.02 XX cord-006870-f5w6fw6q 2553 1 and and CC cord-006870-f5w6fw6q 2553 2 reintubation reintubation NN cord-006870-f5w6fw6q 2553 3 due due IN cord-006870-f5w6fw6q 2553 4 to to IN cord-006870-f5w6fw6q 2553 5 PES PES NNP cord-006870-f5w6fw6q 2553 6 , , , cord-006870-f5w6fw6q 2553 7 ( ( -LRB- cord-006870-f5w6fw6q 2553 8 1 1 CD cord-006870-f5w6fw6q 2553 9 , , , cord-006870-f5w6fw6q 2553 10 N n CD cord-006870-f5w6fw6q 2553 11 = = SYM cord-006870-f5w6fw6q 2553 12 99 99 CD cord-006870-f5w6fw6q 2553 13 ) ) -RRB- cord-006870-f5w6fw6q 2553 14 = = NFP cord-006870-f5w6fw6q 2554 1 8.32 8.32 CD cord-006870-f5w6fw6q 2554 2 , , , cord-006870-f5w6fw6q 2554 3 p<0.005 p<0.005 CD cord-006870-f5w6fw6q 2554 4 . . . cord-006870-f5w6fw6q 2555 1 The the DT cord-006870-f5w6fw6q 2555 2 clinical clinical JJ cord-006870-f5w6fw6q 2555 3 pathway pathway NN cord-006870-f5w6fw6q 2555 4 implemented implement VBN cord-006870-f5w6fw6q 2555 5 in in IN cord-006870-f5w6fw6q 2555 6 our -PRON- PRP$ cord-006870-f5w6fw6q 2555 7 NCCU NCCU NNP cord-006870-f5w6fw6q 2555 8 was be VBD cord-006870-f5w6fw6q 2555 9 safe safe JJ cord-006870-f5w6fw6q 2555 10 and and CC cord-006870-f5w6fw6q 2555 11 effective effective JJ cord-006870-f5w6fw6q 2555 12 in in IN cord-006870-f5w6fw6q 2555 13 reducing reduce VBG cord-006870-f5w6fw6q 2555 14 rates rate NNS cord-006870-f5w6fw6q 2555 15 of of IN cord-006870-f5w6fw6q 2555 16 PES PES NNP cord-006870-f5w6fw6q 2555 17 , , , cord-006870-f5w6fw6q 2555 18 reintubation reintubation NN cord-006870-f5w6fw6q 2555 19 and and CC cord-006870-f5w6fw6q 2555 20 reintubation reintubation NN cord-006870-f5w6fw6q 2555 21 due due IN cord-006870-f5w6fw6q 2555 22 to to IN cord-006870-f5w6fw6q 2555 23 PES PES NNP cord-006870-f5w6fw6q 2555 24 . . . cord-006870-f5w6fw6q 2556 1 Agency Agency NNP cord-006870-f5w6fw6q 2556 2 for for IN cord-006870-f5w6fw6q 2556 3 Healthcare Healthcare NNP cord-006870-f5w6fw6q 2556 4 Research Research NNP cord-006870-f5w6fw6q 2556 5 and and CC cord-006870-f5w6fw6q 2556 6 Quality Quality NNP cord-006870-f5w6fw6q 2556 7 ( ( -LRB- cord-006870-f5w6fw6q 2556 8 AHRQ AHRQ NNP cord-006870-f5w6fw6q 2556 9 ) ) -RRB- cord-006870-f5w6fw6q 2556 10 identified identify VBD cord-006870-f5w6fw6q 2556 11 postoperative postoperative JJ cord-006870-f5w6fw6q 2556 12 deep deep JJ cord-006870-f5w6fw6q 2556 13 vein vein NN cord-006870-f5w6fw6q 2556 14 thrombosis thrombosis NN cord-006870-f5w6fw6q 2556 15 ( ( -LRB- cord-006870-f5w6fw6q 2556 16 DVT DVT NNP cord-006870-f5w6fw6q 2556 17 ) ) -RRB- cord-006870-f5w6fw6q 2556 18 or or CC cord-006870-f5w6fw6q 2556 19 pulmonary pulmonary JJ cord-006870-f5w6fw6q 2556 20 embolism embolism NN cord-006870-f5w6fw6q 2556 21 ( ( -LRB- cord-006870-f5w6fw6q 2556 22 PE PE NNP cord-006870-f5w6fw6q 2556 23 ) ) -RRB- cord-006870-f5w6fw6q 2556 24 , , , cord-006870-f5w6fw6q 2556 25 also also RB cord-006870-f5w6fw6q 2556 26 commonly commonly RB cord-006870-f5w6fw6q 2556 27 referred refer VBN cord-006870-f5w6fw6q 2556 28 to to IN cord-006870-f5w6fw6q 2556 29 as as RB cord-006870-f5w6fw6q 2556 30 venous venous JJ cord-006870-f5w6fw6q 2556 31 thromboembolism thromboembolism NN cord-006870-f5w6fw6q 2556 32 ( ( -LRB- cord-006870-f5w6fw6q 2556 33 VTE VTE NNP cord-006870-f5w6fw6q 2556 34 ) ) -RRB- cord-006870-f5w6fw6q 2556 35 , , , cord-006870-f5w6fw6q 2556 36 as as IN cord-006870-f5w6fw6q 2556 37 one one CD cord-006870-f5w6fw6q 2556 38 of of IN cord-006870-f5w6fw6q 2556 39 the the DT cord-006870-f5w6fw6q 2556 40 complications complication NNS cord-006870-f5w6fw6q 2556 41 acquired acquire VBN cord-006870-f5w6fw6q 2556 42 in in IN cord-006870-f5w6fw6q 2556 43 the the DT cord-006870-f5w6fw6q 2556 44 hospital hospital NN cord-006870-f5w6fw6q 2556 45 and and CC cord-006870-f5w6fw6q 2556 46 thus thus RB cord-006870-f5w6fw6q 2556 47 developed develop VBD cord-006870-f5w6fw6q 2556 48 a a DT cord-006870-f5w6fw6q 2556 49 mechanism mechanism NN cord-006870-f5w6fw6q 2556 50 to to TO cord-006870-f5w6fw6q 2556 51 report report VB cord-006870-f5w6fw6q 2556 52 its -PRON- PRP$ cord-006870-f5w6fw6q 2556 53 rate rate NN cord-006870-f5w6fw6q 2556 54 using use VBG cord-006870-f5w6fw6q 2556 55 administrative administrative JJ cord-006870-f5w6fw6q 2556 56 data datum NNS cord-006870-f5w6fw6q 2556 57 . . . cord-006870-f5w6fw6q 2557 1 Postoperative postoperative JJ cord-006870-f5w6fw6q 2557 2 VTE VTE NNP cord-006870-f5w6fw6q 2557 3 rate rate NN cord-006870-f5w6fw6q 2557 4 reduction reduction NN cord-006870-f5w6fw6q 2557 5 became become VBD cord-006870-f5w6fw6q 2557 6 top top JJ cord-006870-f5w6fw6q 2557 7 priority priority NN cord-006870-f5w6fw6q 2557 8 for for IN cord-006870-f5w6fw6q 2557 9 the the DT cord-006870-f5w6fw6q 2557 10 University University NNP cord-006870-f5w6fw6q 2557 11 of of IN cord-006870-f5w6fw6q 2557 12 Illinois Illinois NNP cord-006870-f5w6fw6q 2557 13 ( ( -LRB- cord-006870-f5w6fw6q 2557 14 UIH uih NN cord-006870-f5w6fw6q 2557 15 ) ) -RRB- cord-006870-f5w6fw6q 2557 16 due due IN cord-006870-f5w6fw6q 2557 17 to to IN cord-006870-f5w6fw6q 2557 18 its -PRON- PRP$ cord-006870-f5w6fw6q 2557 19 high high JJ cord-006870-f5w6fw6q 2557 20 yearly yearly JJ cord-006870-f5w6fw6q 2557 21 rate rate NN cord-006870-f5w6fw6q 2557 22 , , , cord-006870-f5w6fw6q 2557 23 especially especially RB cord-006870-f5w6fw6q 2557 24 among among IN cord-006870-f5w6fw6q 2557 25 patients patient NNS cord-006870-f5w6fw6q 2557 26 in in IN cord-006870-f5w6fw6q 2557 27 the the DT cord-006870-f5w6fw6q 2557 28 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 2557 29 Intensive Intensive NNP cord-006870-f5w6fw6q 2557 30 Care Care NNP cord-006870-f5w6fw6q 2557 31 Unit Unit NNP cord-006870-f5w6fw6q 2557 32 ( ( -LRB- cord-006870-f5w6fw6q 2557 33 NSICU NSICU NNP cord-006870-f5w6fw6q 2557 34 ) ) -RRB- cord-006870-f5w6fw6q 2557 35 . . . cord-006870-f5w6fw6q 2558 1 Therefore therefore RB cord-006870-f5w6fw6q 2558 2 , , , cord-006870-f5w6fw6q 2558 3 a a DT cord-006870-f5w6fw6q 2558 4 quality quality NN cord-006870-f5w6fw6q 2558 5 improvement improvement NN cord-006870-f5w6fw6q 2558 6 team team NN cord-006870-f5w6fw6q 2558 7 in in IN cord-006870-f5w6fw6q 2558 8 the the DT cord-006870-f5w6fw6q 2558 9 NSICU NSICU NNP cord-006870-f5w6fw6q 2558 10 implemented implement VBD cord-006870-f5w6fw6q 2558 11 VTE VTE NNP cord-006870-f5w6fw6q 2558 12 bundle bundle NN cord-006870-f5w6fw6q 2558 13 and and CC cord-006870-f5w6fw6q 2558 14 analyzed analyze VBD cord-006870-f5w6fw6q 2558 15 its -PRON- PRP$ cord-006870-f5w6fw6q 2558 16 effect effect NN cord-006870-f5w6fw6q 2558 17 on on IN cord-006870-f5w6fw6q 2558 18 the the DT cord-006870-f5w6fw6q 2558 19 VTE VTE NNP cord-006870-f5w6fw6q 2558 20 rate rate NN cord-006870-f5w6fw6q 2558 21 . . . cord-006870-f5w6fw6q 2559 1 The the DT cord-006870-f5w6fw6q 2559 2 VTE VTE NNP cord-006870-f5w6fw6q 2559 3 bundle bundle NN cord-006870-f5w6fw6q 2559 4 was be VBD cord-006870-f5w6fw6q 2559 5 initiated initiate VBN cord-006870-f5w6fw6q 2559 6 on on IN cord-006870-f5w6fw6q 2559 7 all all DT cord-006870-f5w6fw6q 2559 8 neurosurgery neurosurgery NNP cord-006870-f5w6fw6q 2559 9 and and CC cord-006870-f5w6fw6q 2559 10 neurology neurology NN cord-006870-f5w6fw6q 2559 11 patients patient NNS cord-006870-f5w6fw6q 2559 12 admitted admit VBD cord-006870-f5w6fw6q 2559 13 to to IN cord-006870-f5w6fw6q 2559 14 the the DT cord-006870-f5w6fw6q 2559 15 NSICU NSICU NNP cord-006870-f5w6fw6q 2559 16 since since IN cord-006870-f5w6fw6q 2559 17 March March NNP cord-006870-f5w6fw6q 2559 18 2016 2016 CD cord-006870-f5w6fw6q 2559 19 . . . cord-006870-f5w6fw6q 2560 1 VTE VTE NNP cord-006870-f5w6fw6q 2560 2 bundle bundle NN cord-006870-f5w6fw6q 2560 3 included include VBD cord-006870-f5w6fw6q 2560 4 lower low JJR cord-006870-f5w6fw6q 2560 5 extremity extremity NN cord-006870-f5w6fw6q 2560 6 Doppler Doppler NNP cord-006870-f5w6fw6q 2560 7 ultrasound ultrasound NN cord-006870-f5w6fw6q 2560 8 within within IN cord-006870-f5w6fw6q 2560 9 24 24 CD cord-006870-f5w6fw6q 2560 10 hours hour NNS cord-006870-f5w6fw6q 2560 11 of of IN cord-006870-f5w6fw6q 2560 12 admission admission NN cord-006870-f5w6fw6q 2560 13 , , , cord-006870-f5w6fw6q 2560 14 VTE VTE NNP cord-006870-f5w6fw6q 2560 15 education education NN cord-006870-f5w6fw6q 2560 16 provided provide VBN cord-006870-f5w6fw6q 2560 17 to to IN cord-006870-f5w6fw6q 2560 18 patient patient NN cord-006870-f5w6fw6q 2560 19 or or CC cord-006870-f5w6fw6q 2560 20 family family NN cord-006870-f5w6fw6q 2560 21 member member NN cord-006870-f5w6fw6q 2560 22 within within IN cord-006870-f5w6fw6q 2560 23 48 48 CD cord-006870-f5w6fw6q 2560 24 hours hour NNS cord-006870-f5w6fw6q 2560 25 of of IN cord-006870-f5w6fw6q 2560 26 admission admission NN cord-006870-f5w6fw6q 2560 27 , , , cord-006870-f5w6fw6q 2560 28 and and CC cord-006870-f5w6fw6q 2560 29 daily daily JJ cord-006870-f5w6fw6q 2560 30 surveillance surveillance NN cord-006870-f5w6fw6q 2560 31 on on IN cord-006870-f5w6fw6q 2560 32 proper proper JJ cord-006870-f5w6fw6q 2560 33 use use NN cord-006870-f5w6fw6q 2560 34 of of IN cord-006870-f5w6fw6q 2560 35 mechanical mechanical JJ cord-006870-f5w6fw6q 2560 36 sleeves sleeve NNS cord-006870-f5w6fw6q 2560 37 and and CC cord-006870-f5w6fw6q 2560 38 the the DT cord-006870-f5w6fw6q 2560 39 mechanical mechanical JJ cord-006870-f5w6fw6q 2560 40 device device NN cord-006870-f5w6fw6q 2560 41 , , , cord-006870-f5w6fw6q 2560 42 low low JJ cord-006870-f5w6fw6q 2560 43 - - HYPH cord-006870-f5w6fw6q 2560 44 dose dose NN cord-006870-f5w6fw6q 2560 45 heparin heparin NN cord-006870-f5w6fw6q 2560 46 initiation initiation NN cord-006870-f5w6fw6q 2560 47 and and CC cord-006870-f5w6fw6q 2560 48 maintenance maintenance NN cord-006870-f5w6fw6q 2560 49 therapy therapy NN cord-006870-f5w6fw6q 2560 50 , , , cord-006870-f5w6fw6q 2560 51 and and CC cord-006870-f5w6fw6q 2560 52 documentation documentation NN cord-006870-f5w6fw6q 2560 53 of of IN cord-006870-f5w6fw6q 2560 54 activity activity NN cord-006870-f5w6fw6q 2560 55 status status NN cord-006870-f5w6fw6q 2560 56 . . . cord-006870-f5w6fw6q 2561 1 The the DT cord-006870-f5w6fw6q 2561 2 nursing nursing NN cord-006870-f5w6fw6q 2561 3 staff staff NN cord-006870-f5w6fw6q 2561 4 were be VBD cord-006870-f5w6fw6q 2561 5 encouraged encourage VBN cord-006870-f5w6fw6q 2561 6 to to TO cord-006870-f5w6fw6q 2561 7 follow follow VB cord-006870-f5w6fw6q 2561 8 the the DT cord-006870-f5w6fw6q 2561 9 early early JJ cord-006870-f5w6fw6q 2561 10 mobilization mobilization NN cord-006870-f5w6fw6q 2561 11 protocol protocol NN cord-006870-f5w6fw6q 2561 12 . . . cord-006870-f5w6fw6q 2562 1 Mean mean JJ cord-006870-f5w6fw6q 2562 2 VTE VTE NNP cord-006870-f5w6fw6q 2562 3 rate rate NN cord-006870-f5w6fw6q 2562 4 was be VBD cord-006870-f5w6fw6q 2562 5 52.9 52.9 CD cord-006870-f5w6fw6q 2562 6 per per IN cord-006870-f5w6fw6q 2562 7 1000 1000 CD cord-006870-f5w6fw6q 2562 8 cases case NNS cord-006870-f5w6fw6q 2562 9 approximately approximately RB cord-006870-f5w6fw6q 2562 10 1-year 1-year CD cord-006870-f5w6fw6q 2562 11 before before RB cord-006870-f5w6fw6q 2562 12 and and CC cord-006870-f5w6fw6q 2562 13 33.6 33.6 CD cord-006870-f5w6fw6q 2562 14 per per IN cord-006870-f5w6fw6q 2562 15 1000 1000 CD cord-006870-f5w6fw6q 2562 16 cases case NNS cord-006870-f5w6fw6q 2562 17 approximately approximately RB cord-006870-f5w6fw6q 2562 18 1-year 1-year CD cord-006870-f5w6fw6q 2562 19 after after IN cord-006870-f5w6fw6q 2562 20 the the DT cord-006870-f5w6fw6q 2562 21 implementation implementation NN cord-006870-f5w6fw6q 2562 22 of of IN cord-006870-f5w6fw6q 2562 23 VTE VTE NNP cord-006870-f5w6fw6q 2562 24 bundle bundle NN cord-006870-f5w6fw6q 2562 25 . . . cord-006870-f5w6fw6q 2563 1 The the DT cord-006870-f5w6fw6q 2563 2 rate rate NN cord-006870-f5w6fw6q 2563 3 of of IN cord-006870-f5w6fw6q 2563 4 compliance compliance NN cord-006870-f5w6fw6q 2563 5 was be VBD cord-006870-f5w6fw6q 2563 6 high high JJ cord-006870-f5w6fw6q 2563 7 on on IN cord-006870-f5w6fw6q 2563 8 all all DT cord-006870-f5w6fw6q 2563 9 aspects aspect NNS cord-006870-f5w6fw6q 2563 10 of of IN cord-006870-f5w6fw6q 2563 11 VTE VTE NNP cord-006870-f5w6fw6q 2563 12 bundle bundle NN cord-006870-f5w6fw6q 2563 13 , , , cord-006870-f5w6fw6q 2563 14 especially especially RB cord-006870-f5w6fw6q 2563 15 on on IN cord-006870-f5w6fw6q 2563 16 correct correct JJ cord-006870-f5w6fw6q 2563 17 placement placement NN cord-006870-f5w6fw6q 2563 18 of of IN cord-006870-f5w6fw6q 2563 19 IPC IPC NNP cord-006870-f5w6fw6q 2563 20 sleeve sleeve NN cord-006870-f5w6fw6q 2563 21 > > XX cord-006870-f5w6fw6q 2563 22 85 85 CD cord-006870-f5w6fw6q 2563 23 % % NN cord-006870-f5w6fw6q 2563 24 ; ; , cord-006870-f5w6fw6q 2563 25 functioning function VBG cord-006870-f5w6fw6q 2563 26 IPC IPC NNP cord-006870-f5w6fw6q 2563 27 device device NN cord-006870-f5w6fw6q 2563 28 > > XX cord-006870-f5w6fw6q 2563 29 90 90 CD cord-006870-f5w6fw6q 2563 30 % % NN cord-006870-f5w6fw6q 2563 31 ; ; , cord-006870-f5w6fw6q 2563 32 low low JJ cord-006870-f5w6fw6q 2563 33 - - HYPH cord-006870-f5w6fw6q 2563 34 dose dose NN cord-006870-f5w6fw6q 2563 35 heparin heparin NN cord-006870-f5w6fw6q 2564 1 > > XX cord-006870-f5w6fw6q 2565 1 90 90 CD cord-006870-f5w6fw6q 2565 2 % % NN cord-006870-f5w6fw6q 2565 3 ; ; , cord-006870-f5w6fw6q 2565 4 documentation documentation NN cord-006870-f5w6fw6q 2565 5 of of IN cord-006870-f5w6fw6q 2565 6 activity activity NN cord-006870-f5w6fw6q 2565 7 status status NN cord-006870-f5w6fw6q 2565 8 > > : cord-006870-f5w6fw6q 2565 9 94 94 CD cord-006870-f5w6fw6q 2565 10 % % NN cord-006870-f5w6fw6q 2565 11 . . . cord-006870-f5w6fw6q 2566 1 No no DT cord-006870-f5w6fw6q 2566 2 adverse adverse JJ cord-006870-f5w6fw6q 2566 3 effects effect NNS cord-006870-f5w6fw6q 2566 4 were be VBD cord-006870-f5w6fw6q 2566 5 noted note VBN cord-006870-f5w6fw6q 2566 6 ( ( -LRB- cord-006870-f5w6fw6q 2566 7 i.e. i.e. FW cord-006870-f5w6fw6q 2566 8 , , , cord-006870-f5w6fw6q 2566 9 skin skin NN cord-006870-f5w6fw6q 2566 10 breakdown breakdown NN cord-006870-f5w6fw6q 2566 11 , , , cord-006870-f5w6fw6q 2566 12 major major JJ cord-006870-f5w6fw6q 2566 13 bleeding bleeding NN cord-006870-f5w6fw6q 2566 14 ) ) -RRB- cord-006870-f5w6fw6q 2566 15 during during IN cord-006870-f5w6fw6q 2566 16 the the DT cord-006870-f5w6fw6q 2566 17 study study NN cord-006870-f5w6fw6q 2566 18 period period NN cord-006870-f5w6fw6q 2566 19 . . . cord-006870-f5w6fw6q 2567 1 This this DT cord-006870-f5w6fw6q 2567 2 was be VBD cord-006870-f5w6fw6q 2567 3 the the DT cord-006870-f5w6fw6q 2567 4 first first JJ cord-006870-f5w6fw6q 2567 5 time time NN cord-006870-f5w6fw6q 2567 6 in in IN cord-006870-f5w6fw6q 2567 7 3 3 CD cord-006870-f5w6fw6q 2567 8 years year NNS cord-006870-f5w6fw6q 2567 9 at at IN cord-006870-f5w6fw6q 2567 10 UIH UIH NNP cord-006870-f5w6fw6q 2567 11 , , , cord-006870-f5w6fw6q 2567 12 the the DT cord-006870-f5w6fw6q 2567 13 postoperative postoperative JJ cord-006870-f5w6fw6q 2567 14 VTE VTE NNP cord-006870-f5w6fw6q 2567 15 rate rate NN cord-006870-f5w6fw6q 2567 16 was be VBD cord-006870-f5w6fw6q 2567 17 reduced reduce VBN cord-006870-f5w6fw6q 2567 18 among among IN cord-006870-f5w6fw6q 2567 19 NSICU NSICU NNP cord-006870-f5w6fw6q 2567 20 patients patient NNS cord-006870-f5w6fw6q 2567 21 based base VBN cord-006870-f5w6fw6q 2567 22 on on IN cord-006870-f5w6fw6q 2567 23 the the DT cord-006870-f5w6fw6q 2567 24 AHRQ AHRQ NNP cord-006870-f5w6fw6q 2567 25 reports report NNS cord-006870-f5w6fw6q 2567 26 . . . cord-006870-f5w6fw6q 2568 1 The the DT cord-006870-f5w6fw6q 2568 2 reduction reduction NN cord-006870-f5w6fw6q 2568 3 may may MD cord-006870-f5w6fw6q 2568 4 partly partly RB cord-006870-f5w6fw6q 2568 5 be be VB cord-006870-f5w6fw6q 2568 6 attributed attribute VBN cord-006870-f5w6fw6q 2568 7 to to IN cord-006870-f5w6fw6q 2568 8 the the DT cord-006870-f5w6fw6q 2568 9 implementation implementation NN cord-006870-f5w6fw6q 2568 10 of of IN cord-006870-f5w6fw6q 2568 11 VTE VTE NNP cord-006870-f5w6fw6q 2568 12 bundle bundle NN cord-006870-f5w6fw6q 2568 13 ; ; : cord-006870-f5w6fw6q 2568 14 however however RB cord-006870-f5w6fw6q 2568 15 further further JJ cord-006870-f5w6fw6q 2568 16 evaluation evaluation NN cord-006870-f5w6fw6q 2568 17 need need NN cord-006870-f5w6fw6q 2568 18 to to TO cord-006870-f5w6fw6q 2568 19 be be VB cord-006870-f5w6fw6q 2568 20 performed perform VBN cord-006870-f5w6fw6q 2568 21 to to TO cord-006870-f5w6fw6q 2568 22 determine determine VB cord-006870-f5w6fw6q 2568 23 the the DT cord-006870-f5w6fw6q 2568 24 effect effect NN cord-006870-f5w6fw6q 2568 25 size size NN cord-006870-f5w6fw6q 2568 26 of of IN cord-006870-f5w6fw6q 2568 27 VTE VTE NNP cord-006870-f5w6fw6q 2568 28 bundle bundle NN cord-006870-f5w6fw6q 2568 29 . . . cord-006870-f5w6fw6q 2569 1 Increasing increase VBG cord-006870-f5w6fw6q 2569 2 evidence evidence NN cord-006870-f5w6fw6q 2569 3 suggests suggest VBZ cord-006870-f5w6fw6q 2569 4 that that IN cord-006870-f5w6fw6q 2569 5 large large JJ cord-006870-f5w6fw6q 2569 6 volume volume NN cord-006870-f5w6fw6q 2569 7 infusions infusion NNS cord-006870-f5w6fw6q 2569 8 of of IN cord-006870-f5w6fw6q 2569 9 0.9 0.9 CD cord-006870-f5w6fw6q 2569 10 % % NN cord-006870-f5w6fw6q 2569 11 sodium sodium NN cord-006870-f5w6fw6q 2569 12 chloride chloride NN cord-006870-f5w6fw6q 2569 13 ( ( -LRB- cord-006870-f5w6fw6q 2569 14 NaCl NaCl NNP cord-006870-f5w6fw6q 2569 15 ) ) -RRB- cord-006870-f5w6fw6q 2569 16 for for IN cord-006870-f5w6fw6q 2569 17 resuscitation resuscitation NN cord-006870-f5w6fw6q 2569 18 are be VBP cord-006870-f5w6fw6q 2569 19 associated associate VBN cord-006870-f5w6fw6q 2569 20 with with IN cord-006870-f5w6fw6q 2569 21 hyperchloremic hyperchloremic JJ cord-006870-f5w6fw6q 2569 22 metabolic metabolic JJ cord-006870-f5w6fw6q 2569 23 acidosis acidosis NN cord-006870-f5w6fw6q 2569 24 and and CC cord-006870-f5w6fw6q 2569 25 renal renal JJ cord-006870-f5w6fw6q 2569 26 vasoconstriction vasoconstriction NN cord-006870-f5w6fw6q 2569 27 leading lead VBG cord-006870-f5w6fw6q 2569 28 to to IN cord-006870-f5w6fw6q 2569 29 an an DT cord-006870-f5w6fw6q 2569 30 increased increase VBN cord-006870-f5w6fw6q 2569 31 risk risk NN cord-006870-f5w6fw6q 2569 32 of of IN cord-006870-f5w6fw6q 2569 33 acute acute JJ cord-006870-f5w6fw6q 2569 34 kidney kidney NN cord-006870-f5w6fw6q 2569 35 injury injury NN cord-006870-f5w6fw6q 2569 36 ( ( -LRB- cord-006870-f5w6fw6q 2569 37 AKI AKI NNP cord-006870-f5w6fw6q 2569 38 ) ) -RRB- cord-006870-f5w6fw6q 2569 39 . . . cord-006870-f5w6fw6q 2570 1 In in IN cord-006870-f5w6fw6q 2570 2 patients patient NNS cord-006870-f5w6fw6q 2570 3 with with IN cord-006870-f5w6fw6q 2570 4 neurologic neurologic JJ cord-006870-f5w6fw6q 2570 5 injury injury NN cord-006870-f5w6fw6q 2570 6 , , , cord-006870-f5w6fw6q 2570 7 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2570 8 ( ( -LRB- cord-006870-f5w6fw6q 2570 9 1.5 1.5 CD cord-006870-f5w6fw6q 2570 10 % % NN cord-006870-f5w6fw6q 2570 11 or or CC cord-006870-f5w6fw6q 2570 12 3 3 CD cord-006870-f5w6fw6q 2570 13 % % NN cord-006870-f5w6fw6q 2570 14 ) ) -RRB- cord-006870-f5w6fw6q 2570 15 NaCl nacl NN cord-006870-f5w6fw6q 2570 16 or or CC cord-006870-f5w6fw6q 2570 17 sodium sodium NN cord-006870-f5w6fw6q 2570 18 acetate acetate NN cord-006870-f5w6fw6q 2570 19 ( ( -LRB- cord-006870-f5w6fw6q 2570 20 NaAcetate NaAcetate NNP cord-006870-f5w6fw6q 2570 21 ) ) -RRB- cord-006870-f5w6fw6q 2570 22 may may MD cord-006870-f5w6fw6q 2570 23 be be VB cord-006870-f5w6fw6q 2570 24 required require VBN cord-006870-f5w6fw6q 2570 25 for for IN cord-006870-f5w6fw6q 2570 26 therapeutic therapeutic JJ cord-006870-f5w6fw6q 2570 27 hypernatremia hypernatremia NN cord-006870-f5w6fw6q 2570 28 , , , cord-006870-f5w6fw6q 2570 29 treatment treatment NN cord-006870-f5w6fw6q 2570 30 of of IN cord-006870-f5w6fw6q 2570 31 cerebral cerebral JJ cord-006870-f5w6fw6q 2570 32 salt salt NN cord-006870-f5w6fw6q 2570 33 wasting waste VBG cord-006870-f5w6fw6q 2570 34 or or CC cord-006870-f5w6fw6q 2570 35 elevated elevated JJ cord-006870-f5w6fw6q 2570 36 intracranial intracranial JJ cord-006870-f5w6fw6q 2570 37 pressure pressure NN cord-006870-f5w6fw6q 2570 38 . . . cord-006870-f5w6fw6q 2571 1 The the DT cord-006870-f5w6fw6q 2571 2 primary primary JJ cord-006870-f5w6fw6q 2571 3 aim aim NN cord-006870-f5w6fw6q 2571 4 of of IN cord-006870-f5w6fw6q 2571 5 this this DT cord-006870-f5w6fw6q 2571 6 study study NN cord-006870-f5w6fw6q 2571 7 was be VBD cord-006870-f5w6fw6q 2571 8 to to TO cord-006870-f5w6fw6q 2571 9 determine determine VB cord-006870-f5w6fw6q 2571 10 the the DT cord-006870-f5w6fw6q 2571 11 incidence incidence NN cord-006870-f5w6fw6q 2571 12 of of IN cord-006870-f5w6fw6q 2571 13 AKI AKI NNP cord-006870-f5w6fw6q 2571 14 in in IN cord-006870-f5w6fw6q 2571 15 neurologically neurologically RB cord-006870-f5w6fw6q 2571 16 injured injure VBN cord-006870-f5w6fw6q 2571 17 patients patient NNS cord-006870-f5w6fw6q 2571 18 receiving receive VBG cord-006870-f5w6fw6q 2571 19 intravenous intravenous JJ cord-006870-f5w6fw6q 2571 20 hypertonic hypertonic NN cord-006870-f5w6fw6q 2571 21 NaCl nacl NN cord-006870-f5w6fw6q 2571 22 and and CC cord-006870-f5w6fw6q 2571 23 in in IN cord-006870-f5w6fw6q 2571 24 those those DT cord-006870-f5w6fw6q 2571 25 who who WP cord-006870-f5w6fw6q 2571 26 were be VBD cord-006870-f5w6fw6q 2571 27 switched switch VBN cord-006870-f5w6fw6q 2571 28 to to IN cord-006870-f5w6fw6q 2571 29 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2571 30 NaAcetate NaAcetate NNP cord-006870-f5w6fw6q 2571 31 based base VBN cord-006870-f5w6fw6q 2571 32 on on IN cord-006870-f5w6fw6q 2571 33 provider provider NN cord-006870-f5w6fw6q 2571 34 preference preference NN cord-006870-f5w6fw6q 2571 35 . . . cord-006870-f5w6fw6q 2572 1 This this DT cord-006870-f5w6fw6q 2572 2 single single JJ cord-006870-f5w6fw6q 2572 3 - - HYPH cord-006870-f5w6fw6q 2572 4 center center NN cord-006870-f5w6fw6q 2572 5 , , , cord-006870-f5w6fw6q 2572 6 retrospective retrospective JJ cord-006870-f5w6fw6q 2572 7 study study NN cord-006870-f5w6fw6q 2572 8 compared compare VBD cord-006870-f5w6fw6q 2572 9 patients patient NNS cord-006870-f5w6fw6q 2572 10 that that WDT cord-006870-f5w6fw6q 2572 11 received receive VBD cord-006870-f5w6fw6q 2572 12 only only RB cord-006870-f5w6fw6q 2572 13 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2572 14 NaCl nacl NN cord-006870-f5w6fw6q 2572 15 to to IN cord-006870-f5w6fw6q 2572 16 patients patient NNS cord-006870-f5w6fw6q 2572 17 that that WDT cord-006870-f5w6fw6q 2572 18 were be VBD cord-006870-f5w6fw6q 2572 19 switched switch VBN cord-006870-f5w6fw6q 2572 20 to to IN cord-006870-f5w6fw6q 2572 21 NaAcetate NaAcetate NNP cord-006870-f5w6fw6q 2572 22 . . . cord-006870-f5w6fw6q 2573 1 Data datum NNS cord-006870-f5w6fw6q 2573 2 was be VBD cord-006870-f5w6fw6q 2573 3 collected collect VBN cord-006870-f5w6fw6q 2573 4 to to TO cord-006870-f5w6fw6q 2573 5 assess assess VB cord-006870-f5w6fw6q 2573 6 renal renal JJ cord-006870-f5w6fw6q 2573 7 function function NN cord-006870-f5w6fw6q 2573 8 , , , cord-006870-f5w6fw6q 2573 9 hyperchloremia hyperchloremia NN cord-006870-f5w6fw6q 2573 10 , , , cord-006870-f5w6fw6q 2573 11 and and CC cord-006870-f5w6fw6q 2573 12 metabolic metabolic JJ cord-006870-f5w6fw6q 2573 13 acidosis acidosis NN cord-006870-f5w6fw6q 2573 14 . . . cord-006870-f5w6fw6q 2574 1 A a DT cord-006870-f5w6fw6q 2574 2 total total NN cord-006870-f5w6fw6q 2574 3 of of IN cord-006870-f5w6fw6q 2574 4 301 301 CD cord-006870-f5w6fw6q 2574 5 patients patient NNS cord-006870-f5w6fw6q 2574 6 were be VBD cord-006870-f5w6fw6q 2574 7 screened screen VBN cord-006870-f5w6fw6q 2574 8 and and CC cord-006870-f5w6fw6q 2574 9 of of IN cord-006870-f5w6fw6q 2574 10 those those DT cord-006870-f5w6fw6q 2574 11 142 142 CD cord-006870-f5w6fw6q 2574 12 were be VBD cord-006870-f5w6fw6q 2574 13 included include VBN cord-006870-f5w6fw6q 2574 14 . . . cord-006870-f5w6fw6q 2575 1 The the DT cord-006870-f5w6fw6q 2575 2 patients patient NNS cord-006870-f5w6fw6q 2575 3 who who WP cord-006870-f5w6fw6q 2575 4 were be VBD cord-006870-f5w6fw6q 2575 5 switched switch VBN cord-006870-f5w6fw6q 2575 6 from from IN cord-006870-f5w6fw6q 2575 7 NaCl NaCl NNP cord-006870-f5w6fw6q 2575 8 to to IN cord-006870-f5w6fw6q 2575 9 NaAcetate NaAcetate NNP cord-006870-f5w6fw6q 2575 10 ( ( -LRB- cord-006870-f5w6fw6q 2575 11 n=45 n=45 NNS cord-006870-f5w6fw6q 2575 12 ) ) -RRB- cord-006870-f5w6fw6q 2575 13 had have VBD cord-006870-f5w6fw6q 2575 14 a a DT cord-006870-f5w6fw6q 2575 15 greater great JJR cord-006870-f5w6fw6q 2575 16 incidence incidence NN cord-006870-f5w6fw6q 2575 17 of of IN cord-006870-f5w6fw6q 2575 18 AKI AKI NNP cord-006870-f5w6fw6q 2575 19 ( ( -LRB- cord-006870-f5w6fw6q 2575 20 27 27 CD cord-006870-f5w6fw6q 2575 21 % % NN cord-006870-f5w6fw6q 2575 22 vs. vs. NN cord-006870-f5w6fw6q 2575 23 6 6 CD cord-006870-f5w6fw6q 2575 24 % % NN cord-006870-f5w6fw6q 2575 25 , , , cord-006870-f5w6fw6q 2575 26 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 2575 27 ) ) -RRB- cord-006870-f5w6fw6q 2575 28 and and CC cord-006870-f5w6fw6q 2575 29 hyperchloremia hyperchloremia NNP cord-006870-f5w6fw6q 2575 30 ( ( -LRB- cord-006870-f5w6fw6q 2575 31 56 56 CD cord-006870-f5w6fw6q 2575 32 % % NN cord-006870-f5w6fw6q 2575 33 vs. vs. IN cord-006870-f5w6fw6q 2575 34 29 29 CD cord-006870-f5w6fw6q 2575 35 % % NN cord-006870-f5w6fw6q 2575 36 , , , cord-006870-f5w6fw6q 2575 37 p p NN cord-006870-f5w6fw6q 2575 38 = = SYM cord-006870-f5w6fw6q 2575 39 0.01 0.01 CD cord-006870-f5w6fw6q 2575 40 ) ) -RRB- cord-006870-f5w6fw6q 2575 41 compared compare VBN cord-006870-f5w6fw6q 2575 42 to to IN cord-006870-f5w6fw6q 2575 43 patients patient NNS cord-006870-f5w6fw6q 2575 44 who who WP cord-006870-f5w6fw6q 2575 45 received receive VBD cord-006870-f5w6fw6q 2575 46 only only RB cord-006870-f5w6fw6q 2575 47 NaCl nacl NN cord-006870-f5w6fw6q 2575 48 ( ( -LRB- cord-006870-f5w6fw6q 2575 49 n=97 n=97 NNS cord-006870-f5w6fw6q 2575 50 ) ) -RRB- cord-006870-f5w6fw6q 2575 51 . . . cord-006870-f5w6fw6q 2576 1 The the DT cord-006870-f5w6fw6q 2576 2 incidence incidence NN cord-006870-f5w6fw6q 2576 3 of of IN cord-006870-f5w6fw6q 2576 4 metabolic metabolic JJ cord-006870-f5w6fw6q 2576 5 acidosis acidosis NN cord-006870-f5w6fw6q 2576 6 was be VBD cord-006870-f5w6fw6q 2576 7 increased increase VBN cord-006870-f5w6fw6q 2576 8 but but CC cord-006870-f5w6fw6q 2576 9 not not RB cord-006870-f5w6fw6q 2576 10 statistically statistically RB cord-006870-f5w6fw6q 2576 11 significant significant JJ cord-006870-f5w6fw6q 2576 12 ( ( -LRB- cord-006870-f5w6fw6q 2576 13 15 15 CD cord-006870-f5w6fw6q 2576 14 % % NN cord-006870-f5w6fw6q 2576 15 vs. vs. IN cord-006870-f5w6fw6q 2576 16 11 11 CD cord-006870-f5w6fw6q 2576 17 % % NN cord-006870-f5w6fw6q 2576 18 , , , cord-006870-f5w6fw6q 2576 19 p p NN cord-006870-f5w6fw6q 2576 20 = = SYM cord-006870-f5w6fw6q 2576 21 0.791 0.791 CD cord-006870-f5w6fw6q 2576 22 ) ) -RRB- cord-006870-f5w6fw6q 2576 23 . . . cord-006870-f5w6fw6q 2577 1 On on IN cord-006870-f5w6fw6q 2577 2 average average JJ cord-006870-f5w6fw6q 2577 3 , , , cord-006870-f5w6fw6q 2577 4 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2577 5 NaCl nacl NN cord-006870-f5w6fw6q 2577 6 was be VBD cord-006870-f5w6fw6q 2577 7 switched switch VBN cord-006870-f5w6fw6q 2577 8 to to IN cord-006870-f5w6fw6q 2577 9 hypertonic hypertonic VB cord-006870-f5w6fw6q 2577 10 NaAcetate NaAcetate NNP cord-006870-f5w6fw6q 2577 11 on on IN cord-006870-f5w6fw6q 2577 12 day day NN cord-006870-f5w6fw6q 2577 13 3 3 CD cord-006870-f5w6fw6q 2577 14 of of IN cord-006870-f5w6fw6q 2577 15 treatment treatment NN cord-006870-f5w6fw6q 2577 16 with with IN cord-006870-f5w6fw6q 2577 17 a a DT cord-006870-f5w6fw6q 2577 18 mean mean JJ cord-006870-f5w6fw6q 2577 19 chloride chloride NN cord-006870-f5w6fw6q 2577 20 of of IN cord-006870-f5w6fw6q 2577 21 115.7 115.7 CD cord-006870-f5w6fw6q 2577 22 mEq mEq NNS cord-006870-f5w6fw6q 2577 23 / / SYM cord-006870-f5w6fw6q 2577 24 L l NN cord-006870-f5w6fw6q 2577 25 at at IN cord-006870-f5w6fw6q 2577 26 the the DT cord-006870-f5w6fw6q 2577 27 time time NN cord-006870-f5w6fw6q 2577 28 of of IN cord-006870-f5w6fw6q 2577 29 the the DT cord-006870-f5w6fw6q 2577 30 switch switch NN cord-006870-f5w6fw6q 2577 31 . . . cord-006870-f5w6fw6q 2578 1 There there EX cord-006870-f5w6fw6q 2578 2 was be VBD cord-006870-f5w6fw6q 2578 3 no no DT cord-006870-f5w6fw6q 2578 4 statistical statistical JJ cord-006870-f5w6fw6q 2578 5 difference difference NN cord-006870-f5w6fw6q 2578 6 in in IN cord-006870-f5w6fw6q 2578 7 the the DT cord-006870-f5w6fw6q 2578 8 administration administration NN cord-006870-f5w6fw6q 2578 9 of of IN cord-006870-f5w6fw6q 2578 10 nephrotoxic nephrotoxic NNP cord-006870-f5w6fw6q 2578 11 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2578 12 , , , cord-006870-f5w6fw6q 2578 13 mannitol mannitol NN cord-006870-f5w6fw6q 2578 14 , , , cord-006870-f5w6fw6q 2578 15 vasopressors vasopressor NNS cord-006870-f5w6fw6q 2578 16 , , , cord-006870-f5w6fw6q 2578 17 or or CC cord-006870-f5w6fw6q 2578 18 contrast contrast NN cord-006870-f5w6fw6q 2578 19 dye dye NN cord-006870-f5w6fw6q 2578 20 between between IN cord-006870-f5w6fw6q 2578 21 the the DT cord-006870-f5w6fw6q 2578 22 two two CD cord-006870-f5w6fw6q 2578 23 groups group NNS cord-006870-f5w6fw6q 2578 24 . . . cord-006870-f5w6fw6q 2579 1 The the DT cord-006870-f5w6fw6q 2579 2 receiver receiver NN cord-006870-f5w6fw6q 2579 3 operating operate VBG cord-006870-f5w6fw6q 2579 4 characteristic characteristic NN cord-006870-f5w6fw6q 2579 5 ( ( -LRB- cord-006870-f5w6fw6q 2579 6 ROC ROC NNP cord-006870-f5w6fw6q 2579 7 ) ) -RRB- cord-006870-f5w6fw6q 2579 8 analysis analysis NN cord-006870-f5w6fw6q 2579 9 demonstrated demonstrate VBD cord-006870-f5w6fw6q 2579 10 that that IN cord-006870-f5w6fw6q 2579 11 if if IN cord-006870-f5w6fw6q 2579 12 a a DT cord-006870-f5w6fw6q 2579 13 patient patient NN cord-006870-f5w6fw6q 2579 14 received receive VBD cord-006870-f5w6fw6q 2579 15 greater great JJR cord-006870-f5w6fw6q 2579 16 than than IN cord-006870-f5w6fw6q 2579 17 2055 2055 CD cord-006870-f5w6fw6q 2579 18 mEq mEq NNS cord-006870-f5w6fw6q 2579 19 of of IN cord-006870-f5w6fw6q 2579 20 chloride chloride NN cord-006870-f5w6fw6q 2579 21 over over IN cord-006870-f5w6fw6q 2579 22 7 7 CD cord-006870-f5w6fw6q 2579 23 days day NNS cord-006870-f5w6fw6q 2579 24 they -PRON- PRP cord-006870-f5w6fw6q 2579 25 were be VBD cord-006870-f5w6fw6q 2579 26 more more RBR cord-006870-f5w6fw6q 2579 27 likely likely JJ cord-006870-f5w6fw6q 2579 28 to to TO cord-006870-f5w6fw6q 2579 29 develop develop VB cord-006870-f5w6fw6q 2579 30 AKI AKI NNP cord-006870-f5w6fw6q 2579 31 ( ( -LRB- cord-006870-f5w6fw6q 2579 32 sensitivity sensitivity NN cord-006870-f5w6fw6q 2579 33 72 72 CD cord-006870-f5w6fw6q 2579 34 % % NN cord-006870-f5w6fw6q 2579 35 , , , cord-006870-f5w6fw6q 2579 36 specificity specificity NN cord-006870-f5w6fw6q 2579 37 70 70 CD cord-006870-f5w6fw6q 2579 38 % % NN cord-006870-f5w6fw6q 2579 39 , , , cord-006870-f5w6fw6q 2579 40 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 2579 41 , , , cord-006870-f5w6fw6q 2579 42 AUC AUC NNP cord-006870-f5w6fw6q 2579 43 0.70 0.70 CD cord-006870-f5w6fw6q 2579 44 ) ) -RRB- cord-006870-f5w6fw6q 2579 45 . . . cord-006870-f5w6fw6q 2580 1 Neurologically neurologically RB cord-006870-f5w6fw6q 2580 2 injured injured JJ cord-006870-f5w6fw6q 2580 3 patients patient NNS cord-006870-f5w6fw6q 2580 4 receiving receive VBG cord-006870-f5w6fw6q 2580 5 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2580 6 sodium sodium NN cord-006870-f5w6fw6q 2580 7 therapy therapy NN cord-006870-f5w6fw6q 2580 8 requiring require VBG cord-006870-f5w6fw6q 2580 9 a a DT cord-006870-f5w6fw6q 2580 10 switch switch NN cord-006870-f5w6fw6q 2580 11 to to IN cord-006870-f5w6fw6q 2580 12 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2580 13 NaAcetate NaAcetate NNP cord-006870-f5w6fw6q 2580 14 had have VBD cord-006870-f5w6fw6q 2580 15 an an DT cord-006870-f5w6fw6q 2580 16 increased increase VBN cord-006870-f5w6fw6q 2580 17 incidence incidence NN cord-006870-f5w6fw6q 2580 18 of of IN cord-006870-f5w6fw6q 2580 19 hyperchloremia hyperchloremia NN cord-006870-f5w6fw6q 2580 20 and and CC cord-006870-f5w6fw6q 2580 21 AKI AKI NNP cord-006870-f5w6fw6q 2580 22 . . . cord-006870-f5w6fw6q 2581 1 In in IN cord-006870-f5w6fw6q 2581 2 - - HYPH cord-006870-f5w6fw6q 2581 3 hospital hospital NN cord-006870-f5w6fw6q 2581 4 complications complication NNS cord-006870-f5w6fw6q 2581 5 following follow VBG cord-006870-f5w6fw6q 2581 6 acute acute JJ cord-006870-f5w6fw6q 2581 7 neurological neurological JJ cord-006870-f5w6fw6q 2581 8 injury injury NN cord-006870-f5w6fw6q 2581 9 has have VBZ cord-006870-f5w6fw6q 2581 10 been be VBN cord-006870-f5w6fw6q 2581 11 a a DT cord-006870-f5w6fw6q 2581 12 topic topic NN cord-006870-f5w6fw6q 2581 13 of of IN cord-006870-f5w6fw6q 2581 14 extensive extensive JJ cord-006870-f5w6fw6q 2581 15 research research NN cord-006870-f5w6fw6q 2581 16 to to TO cord-006870-f5w6fw6q 2581 17 help help VB cord-006870-f5w6fw6q 2581 18 reduce reduce VB cord-006870-f5w6fw6q 2581 19 the the DT cord-006870-f5w6fw6q 2581 20 morbidity morbidity NN cord-006870-f5w6fw6q 2581 21 and and CC cord-006870-f5w6fw6q 2581 22 mortality mortality NN cord-006870-f5w6fw6q 2581 23 among among IN cord-006870-f5w6fw6q 2581 24 the the DT cord-006870-f5w6fw6q 2581 25 patients patient NNS cord-006870-f5w6fw6q 2581 26 . . . cord-006870-f5w6fw6q 2582 1 However however RB cord-006870-f5w6fw6q 2582 2 , , , cord-006870-f5w6fw6q 2582 3 the the DT cord-006870-f5w6fw6q 2582 4 incidence incidence NN cord-006870-f5w6fw6q 2582 5 and and CC cord-006870-f5w6fw6q 2582 6 prevalence prevalence NN cord-006870-f5w6fw6q 2582 7 of of IN cord-006870-f5w6fw6q 2582 8 in in IN cord-006870-f5w6fw6q 2582 9 - - HYPH cord-006870-f5w6fw6q 2582 10 hospital hospital NN cord-006870-f5w6fw6q 2582 11 infections infection NNS cord-006870-f5w6fw6q 2582 12 following follow VBG cord-006870-f5w6fw6q 2582 13 an an DT cord-006870-f5w6fw6q 2582 14 acute acute JJ cord-006870-f5w6fw6q 2582 15 neurological neurological JJ cord-006870-f5w6fw6q 2582 16 injury injury NN cord-006870-f5w6fw6q 2582 17 at at IN cord-006870-f5w6fw6q 2582 18 the the DT cord-006870-f5w6fw6q 2582 19 national national JJ cord-006870-f5w6fw6q 2582 20 level level NN cord-006870-f5w6fw6q 2582 21 has have VBZ cord-006870-f5w6fw6q 2582 22 never never RB cord-006870-f5w6fw6q 2582 23 been be VBN cord-006870-f5w6fw6q 2582 24 studied study VBN cord-006870-f5w6fw6q 2582 25 . . . cord-006870-f5w6fw6q 2583 1 The the DT cord-006870-f5w6fw6q 2583 2 aim aim NN cord-006870-f5w6fw6q 2583 3 of of IN cord-006870-f5w6fw6q 2583 4 our -PRON- PRP$ cord-006870-f5w6fw6q 2583 5 study study NN cord-006870-f5w6fw6q 2583 6 is be VBZ cord-006870-f5w6fw6q 2583 7 to to TO cord-006870-f5w6fw6q 2583 8 determine determine VB cord-006870-f5w6fw6q 2583 9 the the DT cord-006870-f5w6fw6q 2583 10 frequency frequency NN cord-006870-f5w6fw6q 2583 11 and and CC cord-006870-f5w6fw6q 2583 12 prevalence prevalence NN cord-006870-f5w6fw6q 2583 13 of of IN cord-006870-f5w6fw6q 2583 14 in in IN cord-006870-f5w6fw6q 2583 15 - - HYPH cord-006870-f5w6fw6q 2583 16 hospital hospital NN cord-006870-f5w6fw6q 2583 17 complications complication NNS cord-006870-f5w6fw6q 2583 18 among among IN cord-006870-f5w6fw6q 2583 19 different different JJ cord-006870-f5w6fw6q 2583 20 patient patient NN cord-006870-f5w6fw6q 2583 21 groups group NNS cord-006870-f5w6fw6q 2583 22 admitted admit VBD cord-006870-f5w6fw6q 2583 23 following follow VBG cord-006870-f5w6fw6q 2583 24 acute acute JJ cord-006870-f5w6fw6q 2583 25 neurological neurological JJ cord-006870-f5w6fw6q 2583 26 injury injury NN cord-006870-f5w6fw6q 2583 27 . . . cord-006870-f5w6fw6q 2584 1 We -PRON- PRP cord-006870-f5w6fw6q 2584 2 identified identify VBD cord-006870-f5w6fw6q 2584 3 patients patient NNS cord-006870-f5w6fw6q 2584 4 with with IN cord-006870-f5w6fw6q 2584 5 primary primary JJ cord-006870-f5w6fw6q 2584 6 diagnosis diagnosis NN cord-006870-f5w6fw6q 2584 7 of of IN cord-006870-f5w6fw6q 2584 8 ischemic ischemic JJ cord-006870-f5w6fw6q 2584 9 stroke stroke NN cord-006870-f5w6fw6q 2584 10 ( ( -LRB- cord-006870-f5w6fw6q 2584 11 IS be VBZ cord-006870-f5w6fw6q 2584 12 ) ) -RRB- cord-006870-f5w6fw6q 2584 13 , , , cord-006870-f5w6fw6q 2584 14 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 2584 15 stroke stroke NN cord-006870-f5w6fw6q 2584 16 ( ( -LRB- cord-006870-f5w6fw6q 2584 17 SAH SAH NNP cord-006870-f5w6fw6q 2584 18 ) ) -RRB- cord-006870-f5w6fw6q 2584 19 , , , cord-006870-f5w6fw6q 2584 20 intracerebral intracerebral JJ cord-006870-f5w6fw6q 2584 21 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2584 22 ( ( -LRB- cord-006870-f5w6fw6q 2584 23 ICH ICH NNP cord-006870-f5w6fw6q 2584 24 ) ) -RRB- cord-006870-f5w6fw6q 2584 25 , , , cord-006870-f5w6fw6q 2584 26 status status NN cord-006870-f5w6fw6q 2584 27 epilepticus epilepticus NN cord-006870-f5w6fw6q 2584 28 ( ( -LRB- cord-006870-f5w6fw6q 2584 29 SE SE NNP cord-006870-f5w6fw6q 2584 30 ) ) -RRB- cord-006870-f5w6fw6q 2584 31 , , , cord-006870-f5w6fw6q 2584 32 meningitis meningitis NN cord-006870-f5w6fw6q 2584 33 , , , cord-006870-f5w6fw6q 2584 34 encephalitis encephalitis NN cord-006870-f5w6fw6q 2584 35 and and CC cord-006870-f5w6fw6q 2584 36 traumatic traumatic JJ cord-006870-f5w6fw6q 2584 37 brain brain NN cord-006870-f5w6fw6q 2584 38 injury injury NN cord-006870-f5w6fw6q 2584 39 ( ( -LRB- cord-006870-f5w6fw6q 2584 40 TBI TBI NNP cord-006870-f5w6fw6q 2584 41 ) ) -RRB- cord-006870-f5w6fw6q 2584 42 from from IN cord-006870-f5w6fw6q 2584 43 nationwide nationwide JJ cord-006870-f5w6fw6q 2584 44 inpatient inpatient JJ cord-006870-f5w6fw6q 2584 45 database database NN cord-006870-f5w6fw6q 2584 46 ( ( -LRB- cord-006870-f5w6fw6q 2584 47 2011 2011 CD cord-006870-f5w6fw6q 2584 48 - - SYM cord-006870-f5w6fw6q 2584 49 2014 2014 CD cord-006870-f5w6fw6q 2584 50 ) ) -RRB- cord-006870-f5w6fw6q 2584 51 through through IN cord-006870-f5w6fw6q 2584 52 using use VBG cord-006870-f5w6fw6q 2584 53 the the DT cord-006870-f5w6fw6q 2584 54 respective respective JJ cord-006870-f5w6fw6q 2584 55 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 2584 56 codes code NNS cord-006870-f5w6fw6q 2584 57 . . . cord-006870-f5w6fw6q 2585 1 Common common JJ cord-006870-f5w6fw6q 2585 2 in in IN cord-006870-f5w6fw6q 2585 3 - - HYPH cord-006870-f5w6fw6q 2585 4 hospital hospital NN cord-006870-f5w6fw6q 2585 5 complications complication NNS cord-006870-f5w6fw6q 2585 6 among among IN cord-006870-f5w6fw6q 2585 7 the the DT cord-006870-f5w6fw6q 2585 8 above above RB cord-006870-f5w6fw6q 2585 9 - - HYPH cord-006870-f5w6fw6q 2585 10 mentioned mention VBN cord-006870-f5w6fw6q 2585 11 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2585 12 through through IN cord-006870-f5w6fw6q 2585 13 using use VBG cord-006870-f5w6fw6q 2585 14 their -PRON- PRP$ cord-006870-f5w6fw6q 2585 15 respective respective JJ cord-006870-f5w6fw6q 2585 16 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 2585 17 codes code NNS cord-006870-f5w6fw6q 2585 18 Patients patient NNS cord-006870-f5w6fw6q 2585 19 with with IN cord-006870-f5w6fw6q 2585 20 primary primary JJ cord-006870-f5w6fw6q 2585 21 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2585 22 of of IN cord-006870-f5w6fw6q 2585 23 IS is NN cord-006870-f5w6fw6q 2585 24 ( ( -LRB- cord-006870-f5w6fw6q 2585 25 n=1855297 n=1855297 CD cord-006870-f5w6fw6q 2585 26 ) ) -RRB- cord-006870-f5w6fw6q 2585 27 , , , cord-006870-f5w6fw6q 2585 28 SAH SAH NNP cord-006870-f5w6fw6q 2585 29 ( ( -LRB- cord-006870-f5w6fw6q 2585 30 n=101576 n=101576 NNP cord-006870-f5w6fw6q 2585 31 ) ) -RRB- cord-006870-f5w6fw6q 2585 32 , , , cord-006870-f5w6fw6q 2585 33 ICH ICH NNP cord-006870-f5w6fw6q 2585 34 ( ( -LRB- cord-006870-f5w6fw6q 2585 35 n=254758 n=254758 NNP cord-006870-f5w6fw6q 2585 36 ) ) -RRB- cord-006870-f5w6fw6q 2585 37 , , , cord-006870-f5w6fw6q 2585 38 SE SE NNP cord-006870-f5w6fw6q 2585 39 ( ( -LRB- cord-006870-f5w6fw6q 2585 40 n=190701 n=190701 CD cord-006870-f5w6fw6q 2585 41 ) ) -RRB- cord-006870-f5w6fw6q 2585 42 , , , cord-006870-f5w6fw6q 2585 43 Meningitis Meningitis NNP cord-006870-f5w6fw6q 2585 44 ( ( -LRB- cord-006870-f5w6fw6q 2585 45 n=46067 n=46067 NNP cord-006870-f5w6fw6q 2585 46 ) ) -RRB- cord-006870-f5w6fw6q 2585 47 , , , cord-006870-f5w6fw6q 2585 48 Encephalitis encephalitis JJ cord-006870-f5w6fw6q 2585 49 ( ( -LRB- cord-006870-f5w6fw6q 2585 50 n=23839 n=23839 NNP cord-006870-f5w6fw6q 2585 51 ) ) -RRB- cord-006870-f5w6fw6q 2585 52 , , , cord-006870-f5w6fw6q 2585 53 TBI TBI NNP cord-006870-f5w6fw6q 2585 54 ( ( -LRB- cord-006870-f5w6fw6q 2585 55 n=1142155 n=1142155 CD cord-006870-f5w6fw6q 2585 56 ) ) -RRB- cord-006870-f5w6fw6q 2585 57 were be VBD cord-006870-f5w6fw6q 2585 58 identified identify VBN cord-006870-f5w6fw6q 2585 59 . . . cord-006870-f5w6fw6q 2586 1 In in IN cord-006870-f5w6fw6q 2586 2 - - HYPH cord-006870-f5w6fw6q 2586 3 hospital hospital NN cord-006870-f5w6fw6q 2586 4 events event NNS cord-006870-f5w6fw6q 2586 5 such such JJ cord-006870-f5w6fw6q 2586 6 as as IN cord-006870-f5w6fw6q 2586 7 myocardial myocardial JJ cord-006870-f5w6fw6q 2586 8 infarction infarction NN cord-006870-f5w6fw6q 2586 9 ( ( -LRB- cord-006870-f5w6fw6q 2586 10 MI MI NNP cord-006870-f5w6fw6q 2586 11 ) ) -RRB- cord-006870-f5w6fw6q 2586 12 , , , cord-006870-f5w6fw6q 2586 13 sepsis sepsis NN cord-006870-f5w6fw6q 2586 14 , , , cord-006870-f5w6fw6q 2586 15 pneumonia pneumonia NN cord-006870-f5w6fw6q 2586 16 , , , cord-006870-f5w6fw6q 2586 17 deep deep JJ cord-006870-f5w6fw6q 2586 18 venous venous JJ cord-006870-f5w6fw6q 2586 19 thrombosis thrombosis NN cord-006870-f5w6fw6q 2586 20 ( ( -LRB- cord-006870-f5w6fw6q 2586 21 DVT DVT NNP cord-006870-f5w6fw6q 2586 22 ) ) -RRB- cord-006870-f5w6fw6q 2586 23 , , , cord-006870-f5w6fw6q 2586 24 pulmonary pulmonary JJ cord-006870-f5w6fw6q 2586 25 embolism embolism NN cord-006870-f5w6fw6q 2586 26 ( ( -LRB- cord-006870-f5w6fw6q 2586 27 PE PE NNP cord-006870-f5w6fw6q 2586 28 ) ) -RRB- cord-006870-f5w6fw6q 2586 29 , , , cord-006870-f5w6fw6q 2586 30 urinary urinary JJ cord-006870-f5w6fw6q 2586 31 tract tract NN cord-006870-f5w6fw6q 2586 32 infections infection NNS cord-006870-f5w6fw6q 2586 33 ( ( -LRB- cord-006870-f5w6fw6q 2586 34 UTI UTI NNP cord-006870-f5w6fw6q 2586 35 ) ) -RRB- cord-006870-f5w6fw6q 2586 36 , , , cord-006870-f5w6fw6q 2586 37 and and CC cord-006870-f5w6fw6q 2586 38 GI GI NNP cord-006870-f5w6fw6q 2586 39 bleed bleed NN cord-006870-f5w6fw6q 2586 40 were be VBD cord-006870-f5w6fw6q 2586 41 identified identify VBN cord-006870-f5w6fw6q 2586 42 and and CC cord-006870-f5w6fw6q 2586 43 compared compare VBN cord-006870-f5w6fw6q 2586 44 among among IN cord-006870-f5w6fw6q 2586 45 different different JJ cord-006870-f5w6fw6q 2586 46 patient patient NN cord-006870-f5w6fw6q 2586 47 groups group NNS cord-006870-f5w6fw6q 2586 48 . . . cord-006870-f5w6fw6q 2587 1 Patients patient NNS cord-006870-f5w6fw6q 2587 2 with with IN cord-006870-f5w6fw6q 2587 3 SE SE NNP cord-006870-f5w6fw6q 2587 4 were be VBD cord-006870-f5w6fw6q 2587 5 noted note VBN cord-006870-f5w6fw6q 2587 6 to to TO cord-006870-f5w6fw6q 2587 7 experience experience VB cord-006870-f5w6fw6q 2587 8 higher high JJR cord-006870-f5w6fw6q 2587 9 systemic systemic JJ cord-006870-f5w6fw6q 2587 10 complications complication NNS cord-006870-f5w6fw6q 2587 11 , , , cord-006870-f5w6fw6q 2587 12 MI MI NNP cord-006870-f5w6fw6q 2587 13 ( ( -LRB- cord-006870-f5w6fw6q 2587 14 3.6 3.6 CD cord-006870-f5w6fw6q 2587 15 % % NN cord-006870-f5w6fw6q 2587 16 ) ) -RRB- cord-006870-f5w6fw6q 2587 17 , , , cord-006870-f5w6fw6q 2587 18 sepsis sepsis NN cord-006870-f5w6fw6q 2587 19 ( ( -LRB- cord-006870-f5w6fw6q 2587 20 11.2 11.2 CD cord-006870-f5w6fw6q 2587 21 % % NN cord-006870-f5w6fw6q 2587 22 ) ) -RRB- cord-006870-f5w6fw6q 2587 23 , , , cord-006870-f5w6fw6q 2587 24 pneumonia pneumonia NN cord-006870-f5w6fw6q 2587 25 ( ( -LRB- cord-006870-f5w6fw6q 2587 26 8.6 8.6 CD cord-006870-f5w6fw6q 2587 27 % % NN cord-006870-f5w6fw6q 2587 28 ) ) -RRB- cord-006870-f5w6fw6q 2587 29 , , , cord-006870-f5w6fw6q 2587 30 DVT DVT NNP cord-006870-f5w6fw6q 2587 31 ( ( -LRB- cord-006870-f5w6fw6q 2587 32 1.7 1.7 CD cord-006870-f5w6fw6q 2587 33 % % NN cord-006870-f5w6fw6q 2587 34 ) ) -RRB- cord-006870-f5w6fw6q 2587 35 , , , cord-006870-f5w6fw6q 2587 36 UTI UTI NNP cord-006870-f5w6fw6q 2587 37 ( ( -LRB- cord-006870-f5w6fw6q 2587 38 16.2 16.2 CD cord-006870-f5w6fw6q 2587 39 % % NN cord-006870-f5w6fw6q 2587 40 ) ) -RRB- cord-006870-f5w6fw6q 2587 41 , , , cord-006870-f5w6fw6q 2587 42 GI GI NNP cord-006870-f5w6fw6q 2587 43 bleed bleed NN cord-006870-f5w6fw6q 2587 44 ( ( -LRB- cord-006870-f5w6fw6q 2587 45 0.41 0.41 CD cord-006870-f5w6fw6q 2587 46 % % NN cord-006870-f5w6fw6q 2587 47 ) ) -RRB- cord-006870-f5w6fw6q 2587 48 . . . cord-006870-f5w6fw6q 2588 1 Patients patient NNS cord-006870-f5w6fw6q 2588 2 admitted admit VBN cord-006870-f5w6fw6q 2588 3 with with IN cord-006870-f5w6fw6q 2588 4 meningitis meningitis NN cord-006870-f5w6fw6q 2588 5 had have VBD cord-006870-f5w6fw6q 2588 6 a a DT cord-006870-f5w6fw6q 2588 7 higher high JJR cord-006870-f5w6fw6q 2588 8 incidence incidence NN cord-006870-f5w6fw6q 2588 9 of of IN cord-006870-f5w6fw6q 2588 10 sepsis sepsis NN cord-006870-f5w6fw6q 2588 11 ( ( -LRB- cord-006870-f5w6fw6q 2588 12 20.5 20.5 CD cord-006870-f5w6fw6q 2588 13 % % NN cord-006870-f5w6fw6q 2588 14 ) ) -RRB- cord-006870-f5w6fw6q 2588 15 , , , cord-006870-f5w6fw6q 2588 16 pneumonia pneumonia NN cord-006870-f5w6fw6q 2588 17 ( ( -LRB- cord-006870-f5w6fw6q 2588 18 9.0 9.0 CD cord-006870-f5w6fw6q 2588 19 % % NN cord-006870-f5w6fw6q 2588 20 ) ) -RRB- cord-006870-f5w6fw6q 2588 21 , , , cord-006870-f5w6fw6q 2588 22 DVT DVT NNP cord-006870-f5w6fw6q 2588 23 ( ( -LRB- cord-006870-f5w6fw6q 2588 24 2.2 2.2 CD cord-006870-f5w6fw6q 2588 25 % % NN cord-006870-f5w6fw6q 2588 26 ) ) -RRB- cord-006870-f5w6fw6q 2588 27 , , , cord-006870-f5w6fw6q 2588 28 PE PE NNP cord-006870-f5w6fw6q 2588 29 ( ( -LRB- cord-006870-f5w6fw6q 2588 30 1.5 1.5 CD cord-006870-f5w6fw6q 2588 31 % % NN cord-006870-f5w6fw6q 2588 32 ) ) -RRB- cord-006870-f5w6fw6q 2588 33 and and CC cord-006870-f5w6fw6q 2588 34 UTI UTI NNP cord-006870-f5w6fw6q 2588 35 ( ( -LRB- cord-006870-f5w6fw6q 2588 36 12.7 12.7 CD cord-006870-f5w6fw6q 2588 37 % % NN cord-006870-f5w6fw6q 2588 38 ) ) -RRB- cord-006870-f5w6fw6q 2588 39 compared compare VBN cord-006870-f5w6fw6q 2588 40 to to IN cord-006870-f5w6fw6q 2588 41 the the DT cord-006870-f5w6fw6q 2588 42 other other JJ cord-006870-f5w6fw6q 2588 43 groups group NNS cord-006870-f5w6fw6q 2588 44 . . . cord-006870-f5w6fw6q 2589 1 UTI UTI NNP cord-006870-f5w6fw6q 2589 2 was be VBD cord-006870-f5w6fw6q 2589 3 the the DT cord-006870-f5w6fw6q 2589 4 most most RBS cord-006870-f5w6fw6q 2589 5 common common JJ cord-006870-f5w6fw6q 2589 6 in in IN cord-006870-f5w6fw6q 2589 7 - - HYPH cord-006870-f5w6fw6q 2589 8 hospital hospital NN cord-006870-f5w6fw6q 2589 9 complication complication NN cord-006870-f5w6fw6q 2589 10 observed observe VBD cord-006870-f5w6fw6q 2589 11 . . . cord-006870-f5w6fw6q 2590 1 Based base VBN cord-006870-f5w6fw6q 2590 2 on on IN cord-006870-f5w6fw6q 2590 3 our -PRON- PRP$ cord-006870-f5w6fw6q 2590 4 analysis analysis NN cord-006870-f5w6fw6q 2590 5 , , , cord-006870-f5w6fw6q 2590 6 we -PRON- PRP cord-006870-f5w6fw6q 2590 7 report report VBP cord-006870-f5w6fw6q 2590 8 a a DT cord-006870-f5w6fw6q 2590 9 higher high JJR cord-006870-f5w6fw6q 2590 10 incidence incidence NN cord-006870-f5w6fw6q 2590 11 of of IN cord-006870-f5w6fw6q 2590 12 urinary urinary JJ cord-006870-f5w6fw6q 2590 13 tract tract NN cord-006870-f5w6fw6q 2590 14 infections infection NNS cord-006870-f5w6fw6q 2590 15 among among IN cord-006870-f5w6fw6q 2590 16 all all DT cord-006870-f5w6fw6q 2590 17 patients patient NNS cord-006870-f5w6fw6q 2590 18 admitted admit VBD cord-006870-f5w6fw6q 2590 19 following follow VBG cord-006870-f5w6fw6q 2590 20 acute acute JJ cord-006870-f5w6fw6q 2590 21 neurological neurological JJ cord-006870-f5w6fw6q 2590 22 injuries injury NNS cord-006870-f5w6fw6q 2590 23 . . . cord-006870-f5w6fw6q 2591 1 Patients patient NNS cord-006870-f5w6fw6q 2591 2 with with IN cord-006870-f5w6fw6q 2591 3 primary primary JJ cord-006870-f5w6fw6q 2591 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 2591 5 of of IN cord-006870-f5w6fw6q 2591 6 status status NN cord-006870-f5w6fw6q 2591 7 epilepticus epilepticus NN cord-006870-f5w6fw6q 2591 8 experienced experience VBD cord-006870-f5w6fw6q 2591 9 more more JJR cord-006870-f5w6fw6q 2591 10 systemic systemic JJ cord-006870-f5w6fw6q 2591 11 complications complication NNS cord-006870-f5w6fw6q 2591 12 compared compare VBN cord-006870-f5w6fw6q 2591 13 to to IN cord-006870-f5w6fw6q 2591 14 the the DT cord-006870-f5w6fw6q 2591 15 other other JJ cord-006870-f5w6fw6q 2591 16 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2591 17 . . . cord-006870-f5w6fw6q 2592 1 Macroglossia Macroglossia NNP cord-006870-f5w6fw6q 2592 2 is be VBZ cord-006870-f5w6fw6q 2592 3 a a DT cord-006870-f5w6fw6q 2592 4 phenomenon phenomenon NN cord-006870-f5w6fw6q 2592 5 that that WDT cord-006870-f5w6fw6q 2592 6 has have VBZ cord-006870-f5w6fw6q 2592 7 been be VBN cord-006870-f5w6fw6q 2592 8 documented document VBN cord-006870-f5w6fw6q 2592 9 in in IN cord-006870-f5w6fw6q 2592 10 association association NN cord-006870-f5w6fw6q 2592 11 with with IN cord-006870-f5w6fw6q 2592 12 prolonged prolong VBN cord-006870-f5w6fw6q 2592 13 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 2592 14 procedures procedure NNS cord-006870-f5w6fw6q 2592 15 , , , cord-006870-f5w6fw6q 2592 16 brainstem brainstem NN cord-006870-f5w6fw6q 2592 17 injury injury NN cord-006870-f5w6fw6q 2592 18 , , , cord-006870-f5w6fw6q 2592 19 phenobarbital phenobarbital NNP cord-006870-f5w6fw6q 2592 20 administration administration NN cord-006870-f5w6fw6q 2592 21 , , , cord-006870-f5w6fw6q 2592 22 and and CC cord-006870-f5w6fw6q 2592 23 venous venous JJ cord-006870-f5w6fw6q 2592 24 / / SYM cord-006870-f5w6fw6q 2592 25 lymphatic lymphatic JJ cord-006870-f5w6fw6q 2592 26 congestion congestion NN cord-006870-f5w6fw6q 2592 27 of of IN cord-006870-f5w6fw6q 2592 28 the the DT cord-006870-f5w6fw6q 2592 29 tongue tongue NN cord-006870-f5w6fw6q 2592 30 . . . cord-006870-f5w6fw6q 2593 1 However however RB cord-006870-f5w6fw6q 2593 2 , , , cord-006870-f5w6fw6q 2593 3 exact exact JJ cord-006870-f5w6fw6q 2593 4 causation causation NN cord-006870-f5w6fw6q 2593 5 of of IN cord-006870-f5w6fw6q 2593 6 this this DT cord-006870-f5w6fw6q 2593 7 condition condition NN cord-006870-f5w6fw6q 2593 8 in in IN cord-006870-f5w6fw6q 2593 9 the the DT cord-006870-f5w6fw6q 2593 10 neurocritical neurocritical NNP cord-006870-f5w6fw6q 2593 11 care care NN cord-006870-f5w6fw6q 2593 12 population population NN cord-006870-f5w6fw6q 2593 13 remains remain VBZ cord-006870-f5w6fw6q 2593 14 unclear unclear JJ cord-006870-f5w6fw6q 2593 15 . . . cord-006870-f5w6fw6q 2594 1 Patients patient NNS cord-006870-f5w6fw6q 2594 2 with with IN cord-006870-f5w6fw6q 2594 3 macroglossia macroglossia NNP cord-006870-f5w6fw6q 2594 4 face face VBP cord-006870-f5w6fw6q 2594 5 significant significant JJ cord-006870-f5w6fw6q 2594 6 risk risk NN cord-006870-f5w6fw6q 2594 7 for for IN cord-006870-f5w6fw6q 2594 8 airway airway NN cord-006870-f5w6fw6q 2594 9 compromise compromise NN cord-006870-f5w6fw6q 2594 10 . . . cord-006870-f5w6fw6q 2595 1 No no DT cord-006870-f5w6fw6q 2595 2 interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 2595 3 patient patient JJ cord-006870-f5w6fw6q 2595 4 safety safety NN cord-006870-f5w6fw6q 2595 5 and and CC cord-006870-f5w6fw6q 2595 6 management management NN cord-006870-f5w6fw6q 2595 7 protocol protocol NN cord-006870-f5w6fw6q 2595 8 exists exist VBZ cord-006870-f5w6fw6q 2595 9 . . . cord-006870-f5w6fw6q 2596 1 Patients patient NNS cord-006870-f5w6fw6q 2596 2 admitted admit VBD cord-006870-f5w6fw6q 2596 3 to to IN cord-006870-f5w6fw6q 2596 4 two two CD cord-006870-f5w6fw6q 2596 5 Neuro Neuro NNP cord-006870-f5w6fw6q 2596 6 ICU ICU NNP cord-006870-f5w6fw6q 2596 7 's be VBZ cord-006870-f5w6fw6q 2596 8 within within IN cord-006870-f5w6fw6q 2596 9 a a DT cord-006870-f5w6fw6q 2596 10 single single JJ cord-006870-f5w6fw6q 2596 11 health health NN cord-006870-f5w6fw6q 2596 12 system system NN cord-006870-f5w6fw6q 2596 13 between between IN cord-006870-f5w6fw6q 2596 14 2012 2012 CD cord-006870-f5w6fw6q 2596 15 - - SYM cord-006870-f5w6fw6q 2596 16 2017 2017 CD cord-006870-f5w6fw6q 2596 17 were be VBD cord-006870-f5w6fw6q 2596 18 reviewed review VBN cord-006870-f5w6fw6q 2596 19 . . . cord-006870-f5w6fw6q 2597 1 Twenty twenty CD cord-006870-f5w6fw6q 2597 2 - - HYPH cord-006870-f5w6fw6q 2597 3 five five CD cord-006870-f5w6fw6q 2597 4 patients patient NNS cord-006870-f5w6fw6q 2597 5 with with IN cord-006870-f5w6fw6q 2597 6 macroglossia macroglossia NNP cord-006870-f5w6fw6q 2597 7 were be VBD cord-006870-f5w6fw6q 2597 8 identified identify VBN cord-006870-f5w6fw6q 2597 9 . . . cord-006870-f5w6fw6q 2598 1 An an DT cord-006870-f5w6fw6q 2598 2 interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 2598 3 patient patient NN cord-006870-f5w6fw6q 2598 4 management management NN cord-006870-f5w6fw6q 2598 5 protocol protocol NN cord-006870-f5w6fw6q 2598 6 was be VBD cord-006870-f5w6fw6q 2598 7 created create VBN cord-006870-f5w6fw6q 2598 8 , , , cord-006870-f5w6fw6q 2598 9 instituting institute VBG cord-006870-f5w6fw6q 2598 10 airway airway NN cord-006870-f5w6fw6q 2598 11 safety safety NN cord-006870-f5w6fw6q 2598 12 standards standard NNS cord-006870-f5w6fw6q 2598 13 , , , cord-006870-f5w6fw6q 2598 14 oral oral JJ cord-006870-f5w6fw6q 2598 15 care care NN cord-006870-f5w6fw6q 2598 16 directives directive NNS cord-006870-f5w6fw6q 2598 17 , , , cord-006870-f5w6fw6q 2598 18 and and CC cord-006870-f5w6fw6q 2598 19 interventions intervention NNS cord-006870-f5w6fw6q 2598 20 to to TO cord-006870-f5w6fw6q 2598 21 promote promote VB cord-006870-f5w6fw6q 2598 22 symptom symptom NN cord-006870-f5w6fw6q 2598 23 resolution resolution NN cord-006870-f5w6fw6q 2598 24 . . . cord-006870-f5w6fw6q 2599 1 Early early JJ cord-006870-f5w6fw6q 2599 2 consultation consultation NN cord-006870-f5w6fw6q 2599 3 to to IN cord-006870-f5w6fw6q 2599 4 Oral oral JJ cord-006870-f5w6fw6q 2599 5 and and CC cord-006870-f5w6fw6q 2599 6 Maxillofacial maxillofacial JJ cord-006870-f5w6fw6q 2599 7 Surgery surgery NN cord-006870-f5w6fw6q 2599 8 and and CC cord-006870-f5w6fw6q 2599 9 consideration consideration NN cord-006870-f5w6fw6q 2599 10 of of IN cord-006870-f5w6fw6q 2599 11 early early JJ cord-006870-f5w6fw6q 2599 12 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2599 13 was be VBD cord-006870-f5w6fw6q 2599 14 recommended recommend VBN cord-006870-f5w6fw6q 2599 15 . . . cord-006870-f5w6fw6q 2600 1 Seventeen seventeen CD cord-006870-f5w6fw6q 2600 2 patients patient NNS cord-006870-f5w6fw6q 2600 3 ( ( -LRB- cord-006870-f5w6fw6q 2600 4 68 68 CD cord-006870-f5w6fw6q 2600 5 % % NN cord-006870-f5w6fw6q 2600 6 ) ) -RRB- cord-006870-f5w6fw6q 2600 7 were be VBD cord-006870-f5w6fw6q 2600 8 women woman NNS cord-006870-f5w6fw6q 2600 9 . . . cord-006870-f5w6fw6q 2601 1 Age age NN cord-006870-f5w6fw6q 2601 2 ranged range VBD cord-006870-f5w6fw6q 2601 3 from from IN cord-006870-f5w6fw6q 2601 4 20 20 CD cord-006870-f5w6fw6q 2601 5 - - SYM cord-006870-f5w6fw6q 2601 6 81 81 CD cord-006870-f5w6fw6q 2601 7 years year NNS cord-006870-f5w6fw6q 2601 8 . . . cord-006870-f5w6fw6q 2602 1 The the DT cord-006870-f5w6fw6q 2602 2 majority majority NN cord-006870-f5w6fw6q 2602 3 ( ( -LRB- cord-006870-f5w6fw6q 2602 4 16/25 16/25 CD cord-006870-f5w6fw6q 2602 5 ) ) -RRB- cord-006870-f5w6fw6q 2602 6 of of IN cord-006870-f5w6fw6q 2602 7 patients patient NNS cord-006870-f5w6fw6q 2602 8 were be VBD cord-006870-f5w6fw6q 2602 9 African african JJ cord-006870-f5w6fw6q 2602 10 American American NNP cord-006870-f5w6fw6q 2602 11 . . . cord-006870-f5w6fw6q 2603 1 Primary primary JJ cord-006870-f5w6fw6q 2603 2 diagnoses diagnosis NNS cord-006870-f5w6fw6q 2603 3 included include VBD cord-006870-f5w6fw6q 2603 4 status status NN cord-006870-f5w6fw6q 2603 5 epilepticus epilepticus NN cord-006870-f5w6fw6q 2603 6 ( ( -LRB- cord-006870-f5w6fw6q 2603 7 12/25 12/25 CD cord-006870-f5w6fw6q 2603 8 ) ) -RRB- cord-006870-f5w6fw6q 2603 9 and and CC cord-006870-f5w6fw6q 2603 10 stroke stroke NN cord-006870-f5w6fw6q 2603 11 ( ( -LRB- cord-006870-f5w6fw6q 2603 12 1 1 CD cord-006870-f5w6fw6q 2603 13 SAH SAH NNP cord-006870-f5w6fw6q 2603 14 , , , cord-006870-f5w6fw6q 2603 15 4 4 CD cord-006870-f5w6fw6q 2603 16 AIS AIS NNP cord-006870-f5w6fw6q 2603 17 , , , cord-006870-f5w6fw6q 2603 18 6 6 CD cord-006870-f5w6fw6q 2603 19 ICH ICH NNP cord-006870-f5w6fw6q 2603 20 ) ) -RRB- cord-006870-f5w6fw6q 2603 21 . . . cord-006870-f5w6fw6q 2604 1 Nineteen nineteen CD cord-006870-f5w6fw6q 2604 2 patients patient NNS cord-006870-f5w6fw6q 2604 3 received receive VBD cord-006870-f5w6fw6q 2604 4 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 2604 5 medications medication NNS cord-006870-f5w6fw6q 2604 6 before before IN cord-006870-f5w6fw6q 2604 7 diagnosis diagnosis NN cord-006870-f5w6fw6q 2604 8 . . . cord-006870-f5w6fw6q 2605 1 Average average JJ cord-006870-f5w6fw6q 2605 2 GCS GCS NNP cord-006870-f5w6fw6q 2605 3 at at IN cord-006870-f5w6fw6q 2605 4 symptom symptom NN cord-006870-f5w6fw6q 2605 5 onset onset NN cord-006870-f5w6fw6q 2605 6 was be VBD cord-006870-f5w6fw6q 2605 7 5.8 5.8 CD cord-006870-f5w6fw6q 2605 8 [ [ -LRB- cord-006870-f5w6fw6q 2605 9 3 3 CD cord-006870-f5w6fw6q 2605 10 ] ] -RRB- cord-006870-f5w6fw6q 2605 11 [ [ -LRB- cord-006870-f5w6fw6q 2605 12 4 4 CD cord-006870-f5w6fw6q 2605 13 ] ] -RRB- cord-006870-f5w6fw6q 2605 14 [ [ -LRB- cord-006870-f5w6fw6q 2605 15 5 5 CD cord-006870-f5w6fw6q 2605 16 ] ] -RRB- cord-006870-f5w6fw6q 2605 17 [ [ -LRB- cord-006870-f5w6fw6q 2605 18 6 6 CD cord-006870-f5w6fw6q 2605 19 ] ] -RRB- cord-006870-f5w6fw6q 2605 20 [ [ -LRB- cord-006870-f5w6fw6q 2605 21 7 7 CD cord-006870-f5w6fw6q 2605 22 ] ] -RRB- cord-006870-f5w6fw6q 2605 23 [ [ -LRB- cord-006870-f5w6fw6q 2605 24 8 8 CD cord-006870-f5w6fw6q 2605 25 ] ] -RRB- cord-006870-f5w6fw6q 2605 26 [ [ -LRB- cord-006870-f5w6fw6q 2605 27 9 9 CD cord-006870-f5w6fw6q 2605 28 ] ] -RRB- cord-006870-f5w6fw6q 2605 29 [ [ -LRB- cord-006870-f5w6fw6q 2605 30 10 10 CD cord-006870-f5w6fw6q 2605 31 ] ] -RRB- cord-006870-f5w6fw6q 2605 32 [ [ -LRB- cord-006870-f5w6fw6q 2605 33 11 11 CD cord-006870-f5w6fw6q 2605 34 ] ] -RRB- cord-006870-f5w6fw6q 2605 35 and and CC cord-006870-f5w6fw6q 2605 36 at at IN cord-006870-f5w6fw6q 2605 37 time time NN cord-006870-f5w6fw6q 2605 38 of of IN cord-006870-f5w6fw6q 2605 39 discharge discharge NN cord-006870-f5w6fw6q 2605 40 was be VBD cord-006870-f5w6fw6q 2605 41 8.9 8.9 CD cord-006870-f5w6fw6q 2605 42 [ [ -LRB- cord-006870-f5w6fw6q 2605 43 3 3 CD cord-006870-f5w6fw6q 2605 44 ] ] -RRB- cord-006870-f5w6fw6q 2605 45 [ [ -LRB- cord-006870-f5w6fw6q 2605 46 4 4 CD cord-006870-f5w6fw6q 2605 47 ] ] -RRB- cord-006870-f5w6fw6q 2605 48 [ [ -LRB- cord-006870-f5w6fw6q 2605 49 5 5 CD cord-006870-f5w6fw6q 2605 50 ] ] -RRB- cord-006870-f5w6fw6q 2605 51 [ [ -LRB- cord-006870-f5w6fw6q 2605 52 6 6 CD cord-006870-f5w6fw6q 2605 53 ] ] -RRB- cord-006870-f5w6fw6q 2605 54 [ [ -LRB- cord-006870-f5w6fw6q 2605 55 7 7 CD cord-006870-f5w6fw6q 2605 56 ] ] -RRB- cord-006870-f5w6fw6q 2605 57 [ [ -LRB- cord-006870-f5w6fw6q 2605 58 8 8 CD cord-006870-f5w6fw6q 2605 59 ] ] -RRB- cord-006870-f5w6fw6q 2605 60 [ [ -LRB- cord-006870-f5w6fw6q 2605 61 9 9 CD cord-006870-f5w6fw6q 2605 62 ] ] -RRB- cord-006870-f5w6fw6q 2605 63 [ [ -LRB- cord-006870-f5w6fw6q 2605 64 10 10 CD cord-006870-f5w6fw6q 2605 65 ] ] -RRB- cord-006870-f5w6fw6q 2605 66 [ [ -LRB- cord-006870-f5w6fw6q 2605 67 11 11 CD cord-006870-f5w6fw6q 2605 68 ] ] -RRB- cord-006870-f5w6fw6q 2605 69 [ [ -LRB- cord-006870-f5w6fw6q 2605 70 12 12 CD cord-006870-f5w6fw6q 2605 71 ] ] -RRB- cord-006870-f5w6fw6q 2605 72 [ [ -LRB- cord-006870-f5w6fw6q 2605 73 13 13 CD cord-006870-f5w6fw6q 2605 74 ] ] -RRB- cord-006870-f5w6fw6q 2605 75 [ [ -LRB- cord-006870-f5w6fw6q 2605 76 14 14 CD cord-006870-f5w6fw6q 2605 77 ] ] -RRB- cord-006870-f5w6fw6q 2605 78 [ [ -LRB- cord-006870-f5w6fw6q 2605 79 15 15 CD cord-006870-f5w6fw6q 2605 80 ] ] -RRB- cord-006870-f5w6fw6q 2605 81 . . . cord-006870-f5w6fw6q 2606 1 Median median JJ cord-006870-f5w6fw6q 2606 2 symptom symptom NN cord-006870-f5w6fw6q 2606 3 onset onset NN cord-006870-f5w6fw6q 2606 4 was be VBD cord-006870-f5w6fw6q 2606 5 hospital hospital NN cord-006870-f5w6fw6q 2606 6 day day NN cord-006870-f5w6fw6q 2606 7 5 5 CD cord-006870-f5w6fw6q 2606 8 [ [ -LRB- cord-006870-f5w6fw6q 2606 9 0 0 CD cord-006870-f5w6fw6q 2606 10 - - SYM cord-006870-f5w6fw6q 2606 11 39 39 CD cord-006870-f5w6fw6q 2606 12 ] ] -RRB- cord-006870-f5w6fw6q 2606 13 . . . cord-006870-f5w6fw6q 2607 1 Twenty twenty CD cord-006870-f5w6fw6q 2607 2 patients patient NNS cord-006870-f5w6fw6q 2607 3 ( ( -LRB- cord-006870-f5w6fw6q 2607 4 80 80 CD cord-006870-f5w6fw6q 2607 5 % % NN cord-006870-f5w6fw6q 2607 6 ) ) -RRB- cord-006870-f5w6fw6q 2607 7 required require VBN cord-006870-f5w6fw6q 2607 8 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2607 9 . . . cord-006870-f5w6fw6q 2608 1 Nine nine CD cord-006870-f5w6fw6q 2608 2 ( ( -LRB- cord-006870-f5w6fw6q 2608 3 36 36 CD cord-006870-f5w6fw6q 2608 4 % % NN cord-006870-f5w6fw6q 2608 5 ) ) -RRB- cord-006870-f5w6fw6q 2608 6 experienced experienced JJ cord-006870-f5w6fw6q 2608 7 symptom symptom NN cord-006870-f5w6fw6q 2608 8 resolution resolution NN cord-006870-f5w6fw6q 2608 9 by by IN cord-006870-f5w6fw6q 2608 10 hospital hospital NN cord-006870-f5w6fw6q 2608 11 discharge discharge NN cord-006870-f5w6fw6q 2608 12 . . . cord-006870-f5w6fw6q 2609 1 Two two CD cord-006870-f5w6fw6q 2609 2 patients patient NNS cord-006870-f5w6fw6q 2609 3 received receive VBD cord-006870-f5w6fw6q 2609 4 botulinum botulinum NN cord-006870-f5w6fw6q 2609 5 toxin toxin NN cord-006870-f5w6fw6q 2609 6 injection injection NN cord-006870-f5w6fw6q 2609 7 ; ; : cord-006870-f5w6fw6q 2609 8 both both CC cord-006870-f5w6fw6q 2609 9 experienced experienced JJ cord-006870-f5w6fw6q 2609 10 symptom symptom NN cord-006870-f5w6fw6q 2609 11 resolution resolution NN cord-006870-f5w6fw6q 2609 12 . . . cord-006870-f5w6fw6q 2610 1 Lingual lingual JJ cord-006870-f5w6fw6q 2610 2 massage massage NN cord-006870-f5w6fw6q 2610 3 was be VBD cord-006870-f5w6fw6q 2610 4 performed perform VBN cord-006870-f5w6fw6q 2610 5 in in IN cord-006870-f5w6fw6q 2610 6 two two CD cord-006870-f5w6fw6q 2610 7 patients patient NNS cord-006870-f5w6fw6q 2610 8 ; ; : cord-006870-f5w6fw6q 2610 9 in in IN cord-006870-f5w6fw6q 2610 10 both both DT cord-006870-f5w6fw6q 2610 11 patients patient NNS cord-006870-f5w6fw6q 2610 12 , , , cord-006870-f5w6fw6q 2610 13 tongue tongue NN cord-006870-f5w6fw6q 2610 14 swelling swelling NN cord-006870-f5w6fw6q 2610 15 resolved resolve VBN cord-006870-f5w6fw6q 2610 16 . . . cord-006870-f5w6fw6q 2611 1 Tongue tongue NN cord-006870-f5w6fw6q 2611 2 lacerations laceration NNS cord-006870-f5w6fw6q 2611 3 occurred occur VBD cord-006870-f5w6fw6q 2611 4 in in IN cord-006870-f5w6fw6q 2611 5 10/25 10/25 CD cord-006870-f5w6fw6q 2611 6 patients patient NNS cord-006870-f5w6fw6q 2611 7 ( ( -LRB- cord-006870-f5w6fw6q 2611 8 40 40 CD cord-006870-f5w6fw6q 2611 9 % % NN cord-006870-f5w6fw6q 2611 10 ) ) -RRB- cord-006870-f5w6fw6q 2611 11 , , , cord-006870-f5w6fw6q 2611 12 although although IN cord-006870-f5w6fw6q 2611 13 most most JJS cord-006870-f5w6fw6q 2611 14 were be VBD cord-006870-f5w6fw6q 2611 15 observed observe VBN cord-006870-f5w6fw6q 2611 16 following follow VBG cord-006870-f5w6fw6q 2611 17 macroglossia macroglossia NNP cord-006870-f5w6fw6q 2611 18 onset onset NN cord-006870-f5w6fw6q 2611 19 , , , cord-006870-f5w6fw6q 2611 20 ruling rule VBG cord-006870-f5w6fw6q 2611 21 out out RP cord-006870-f5w6fw6q 2611 22 trauma trauma NN cord-006870-f5w6fw6q 2611 23 as as IN cord-006870-f5w6fw6q 2611 24 an an DT cord-006870-f5w6fw6q 2611 25 inciting incite VBG cord-006870-f5w6fw6q 2611 26 event event NN cord-006870-f5w6fw6q 2611 27 . . . cord-006870-f5w6fw6q 2612 1 Chlorhexidine chlorhexidine JJ cord-006870-f5w6fw6q 2612 2 oral oral JJ cord-006870-f5w6fw6q 2612 3 rinse rinse NN cord-006870-f5w6fw6q 2612 4 was be VBD cord-006870-f5w6fw6q 2612 5 discontinued discontinue VBN cord-006870-f5w6fw6q 2612 6 for for IN cord-006870-f5w6fw6q 2612 7 all all DT cord-006870-f5w6fw6q 2612 8 except except IN cord-006870-f5w6fw6q 2612 9 five five CD cord-006870-f5w6fw6q 2612 10 patients patient NNS cord-006870-f5w6fw6q 2612 11 due due JJ cord-006870-f5w6fw6q 2612 12 to to IN cord-006870-f5w6fw6q 2612 13 concern concern NN cord-006870-f5w6fw6q 2612 14 for for IN cord-006870-f5w6fw6q 2612 15 angioedema angioedema NN cord-006870-f5w6fw6q 2612 16 . . . cord-006870-f5w6fw6q 2613 1 Endotracheal endotracheal NN cord-006870-f5w6fw6q 2613 2 tube tube NN cord-006870-f5w6fw6q 2613 3 was be VBD cord-006870-f5w6fw6q 2613 4 dislodged dislodge VBN cord-006870-f5w6fw6q 2613 5 in in IN cord-006870-f5w6fw6q 2613 6 two two CD cord-006870-f5w6fw6q 2613 7 patients patient NNS cord-006870-f5w6fw6q 2613 8 , , , cord-006870-f5w6fw6q 2613 9 complicating complicate VBG cord-006870-f5w6fw6q 2613 10 reintubation reintubation NN cord-006870-f5w6fw6q 2613 11 , , , cord-006870-f5w6fw6q 2613 12 although although IN cord-006870-f5w6fw6q 2613 13 successful successful JJ cord-006870-f5w6fw6q 2613 14 . . . cord-006870-f5w6fw6q 2614 1 No no DT cord-006870-f5w6fw6q 2614 2 trend trend NN cord-006870-f5w6fw6q 2614 3 in in IN cord-006870-f5w6fw6q 2614 4 pre pre JJ cord-006870-f5w6fw6q 2614 5 - - JJ cord-006870-f5w6fw6q 2614 6 existing existing JJ cord-006870-f5w6fw6q 2614 7 allergies allergy NNS cord-006870-f5w6fw6q 2614 8 or or CC cord-006870-f5w6fw6q 2614 9 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2614 10 regimen regimen NN cord-006870-f5w6fw6q 2614 11 was be VBD cord-006870-f5w6fw6q 2614 12 apparent apparent JJ cord-006870-f5w6fw6q 2614 13 . . . cord-006870-f5w6fw6q 2615 1 Macroglossia Macroglossia NNP cord-006870-f5w6fw6q 2615 2 is be VBZ cord-006870-f5w6fw6q 2615 3 a a DT cord-006870-f5w6fw6q 2615 4 relatively relatively RB cord-006870-f5w6fw6q 2615 5 uncommon uncommon JJ cord-006870-f5w6fw6q 2615 6 but but CC cord-006870-f5w6fw6q 2615 7 high high JJ cord-006870-f5w6fw6q 2615 8 - - HYPH cord-006870-f5w6fw6q 2615 9 risk risk NN cord-006870-f5w6fw6q 2615 10 condition condition NN cord-006870-f5w6fw6q 2615 11 in in IN cord-006870-f5w6fw6q 2615 12 the the DT cord-006870-f5w6fw6q 2615 13 Neuro Neuro NNP cord-006870-f5w6fw6q 2615 14 ICU ICU NNP cord-006870-f5w6fw6q 2615 15 that that IN cord-006870-f5w6fw6q 2615 16 warrants warrant VBZ cord-006870-f5w6fw6q 2615 17 further further JJ cord-006870-f5w6fw6q 2615 18 study study NN cord-006870-f5w6fw6q 2615 19 . . . cord-006870-f5w6fw6q 2616 1 Care care NN cord-006870-f5w6fw6q 2616 2 of of IN cord-006870-f5w6fw6q 2616 3 patients patient NNS cord-006870-f5w6fw6q 2616 4 with with IN cord-006870-f5w6fw6q 2616 5 macroglossia macroglossia NNP cord-006870-f5w6fw6q 2616 6 should should MD cord-006870-f5w6fw6q 2616 7 be be VB cord-006870-f5w6fw6q 2616 8 standardized standardize VBN cord-006870-f5w6fw6q 2616 9 in in IN cord-006870-f5w6fw6q 2616 10 order order NN cord-006870-f5w6fw6q 2616 11 to to TO cord-006870-f5w6fw6q 2616 12 ensure ensure VB cord-006870-f5w6fw6q 2616 13 airway airway NN cord-006870-f5w6fw6q 2616 14 safety safety NN cord-006870-f5w6fw6q 2616 15 . . . cord-006870-f5w6fw6q 2617 1 An an DT cord-006870-f5w6fw6q 2617 2 interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 2617 3 approach approach NN cord-006870-f5w6fw6q 2617 4 is be VBZ cord-006870-f5w6fw6q 2617 5 recommended recommend VBN cord-006870-f5w6fw6q 2617 6 . . . cord-006870-f5w6fw6q 2618 1 One one CD cord-006870-f5w6fw6q 2618 2 of of IN cord-006870-f5w6fw6q 2618 3 the the DT cord-006870-f5w6fw6q 2618 4 biggest big JJS cord-006870-f5w6fw6q 2618 5 challenges challenge NNS cord-006870-f5w6fw6q 2618 6 of of IN cord-006870-f5w6fw6q 2618 7 magnetic magnetic JJ cord-006870-f5w6fw6q 2618 8 resonance resonance NN cord-006870-f5w6fw6q 2618 9 imaging imaging NN cord-006870-f5w6fw6q 2618 10 ( ( -LRB- cord-006870-f5w6fw6q 2618 11 MRI MRI NNP cord-006870-f5w6fw6q 2618 12 ) ) -RRB- cord-006870-f5w6fw6q 2618 13 examination examination NN cord-006870-f5w6fw6q 2618 14 is be VBZ cord-006870-f5w6fw6q 2618 15 the the DT cord-006870-f5w6fw6q 2618 16 acquisition acquisition NN cord-006870-f5w6fw6q 2618 17 of of IN cord-006870-f5w6fw6q 2618 18 high high JJ cord-006870-f5w6fw6q 2618 19 - - HYPH cord-006870-f5w6fw6q 2618 20 quality quality NN cord-006870-f5w6fw6q 2618 21 diagnostic diagnostic JJ cord-006870-f5w6fw6q 2618 22 images image NNS cord-006870-f5w6fw6q 2618 23 , , , cord-006870-f5w6fw6q 2618 24 as as IN cord-006870-f5w6fw6q 2618 25 it -PRON- PRP cord-006870-f5w6fw6q 2618 26 requires require VBZ cord-006870-f5w6fw6q 2618 27 the the DT cord-006870-f5w6fw6q 2618 28 neurological neurological JJ cord-006870-f5w6fw6q 2618 29 intensive intensive JJ cord-006870-f5w6fw6q 2618 30 care care NN cord-006870-f5w6fw6q 2618 31 unit unit NN cord-006870-f5w6fw6q 2618 32 ( ( -LRB- cord-006870-f5w6fw6q 2618 33 NICU NICU NNP cord-006870-f5w6fw6q 2618 34 ) ) -RRB- cord-006870-f5w6fw6q 2618 35 patients patient NNS cord-006870-f5w6fw6q 2618 36 to to TO cord-006870-f5w6fw6q 2618 37 keep keep VB cord-006870-f5w6fw6q 2618 38 still still RB cord-006870-f5w6fw6q 2618 39 for for IN cord-006870-f5w6fw6q 2618 40 a a DT cord-006870-f5w6fw6q 2618 41 significant significant JJ cord-006870-f5w6fw6q 2618 42 time time NN cord-006870-f5w6fw6q 2618 43 . . . cord-006870-f5w6fw6q 2619 1 In in IN cord-006870-f5w6fw6q 2619 2 situations situation NNS cord-006870-f5w6fw6q 2619 3 with with IN cord-006870-f5w6fw6q 2619 4 poor poor JJ cord-006870-f5w6fw6q 2619 5 patient patient NN cord-006870-f5w6fw6q 2619 6 cooperation cooperation NN cord-006870-f5w6fw6q 2619 7 , , , cord-006870-f5w6fw6q 2619 8 unplanned unplanned JJ cord-006870-f5w6fw6q 2619 9 sedation sedation NN cord-006870-f5w6fw6q 2619 10 is be VBZ cord-006870-f5w6fw6q 2619 11 inevitable inevitable JJ cord-006870-f5w6fw6q 2619 12 , , , cord-006870-f5w6fw6q 2619 13 which which WDT cord-006870-f5w6fw6q 2619 14 can can MD cord-006870-f5w6fw6q 2619 15 lead lead VB cord-006870-f5w6fw6q 2619 16 to to IN cord-006870-f5w6fw6q 2619 17 complications complication NNS cord-006870-f5w6fw6q 2619 18 such such JJ cord-006870-f5w6fw6q 2619 19 as as IN cord-006870-f5w6fw6q 2619 20 desaturation desaturation NN cord-006870-f5w6fw6q 2619 21 and and CC cord-006870-f5w6fw6q 2619 22 hypotension hypotension NN cord-006870-f5w6fw6q 2619 23 . . . cord-006870-f5w6fw6q 2620 1 We -PRON- PRP cord-006870-f5w6fw6q 2620 2 investigated investigate VBD cord-006870-f5w6fw6q 2620 3 the the DT cord-006870-f5w6fw6q 2620 4 incidence incidence NN cord-006870-f5w6fw6q 2620 5 and and CC cord-006870-f5w6fw6q 2620 6 factors factor NNS cord-006870-f5w6fw6q 2620 7 related relate VBN cord-006870-f5w6fw6q 2620 8 to to IN cord-006870-f5w6fw6q 2620 9 complicated complicated JJ cord-006870-f5w6fw6q 2620 10 MRI MRI NNP cord-006870-f5w6fw6q 2620 11 examinations examination NNS cord-006870-f5w6fw6q 2620 12 ( ( -LRB- cord-006870-f5w6fw6q 2620 13 MRI MRI NNP cord-006870-f5w6fw6q 2620 14 - - HYPH cord-006870-f5w6fw6q 2620 15 c c NNP cord-006870-f5w6fw6q 2620 16 ) ) -RRB- cord-006870-f5w6fw6q 2620 17 in in IN cord-006870-f5w6fw6q 2620 18 patients patient NNS cord-006870-f5w6fw6q 2620 19 admitted admit VBN cord-006870-f5w6fw6q 2620 20 to to IN cord-006870-f5w6fw6q 2620 21 the the DT cord-006870-f5w6fw6q 2620 22 NICU NICU NNP cord-006870-f5w6fw6q 2620 23 . . . cord-006870-f5w6fw6q 2621 1 We -PRON- PRP cord-006870-f5w6fw6q 2621 2 designed design VBD cord-006870-f5w6fw6q 2621 3 a a DT cord-006870-f5w6fw6q 2621 4 retrospective retrospective JJ cord-006870-f5w6fw6q 2621 5 study study NN cord-006870-f5w6fw6q 2621 6 to to TO cord-006870-f5w6fw6q 2621 7 review review VB cord-006870-f5w6fw6q 2621 8 the the DT cord-006870-f5w6fw6q 2621 9 data datum NNS cord-006870-f5w6fw6q 2621 10 of of IN cord-006870-f5w6fw6q 2621 11 218 218 CD cord-006870-f5w6fw6q 2621 12 patients patient NNS cord-006870-f5w6fw6q 2621 13 who who WP cord-006870-f5w6fw6q 2621 14 had have VBD cord-006870-f5w6fw6q 2621 15 an an DT cord-006870-f5w6fw6q 2621 16 attempt attempt NN cord-006870-f5w6fw6q 2621 17 to to TO cord-006870-f5w6fw6q 2621 18 undergo undergo VB cord-006870-f5w6fw6q 2621 19 brain brain NN cord-006870-f5w6fw6q 2621 20 MRI MRI NNP cord-006870-f5w6fw6q 2621 21 during during IN cord-006870-f5w6fw6q 2621 22 stay stay NN cord-006870-f5w6fw6q 2621 23 in in IN cord-006870-f5w6fw6q 2621 24 the the DT cord-006870-f5w6fw6q 2621 25 NICU NICU NNP cord-006870-f5w6fw6q 2621 26 between between IN cord-006870-f5w6fw6q 2621 27 July July NNP cord-006870-f5w6fw6q 2621 28 2014 2014 CD cord-006870-f5w6fw6q 2621 29 and and CC cord-006870-f5w6fw6q 2621 30 August August NNP cord-006870-f5w6fw6q 2621 31 2016 2016 CD cord-006870-f5w6fw6q 2621 32 . . . cord-006870-f5w6fw6q 2622 1 The the DT cord-006870-f5w6fw6q 2622 2 MRI MRI NNP cord-006870-f5w6fw6q 2622 3 - - HYPH cord-006870-f5w6fw6q 2622 4 c c NNP cord-006870-f5w6fw6q 2622 5 group group NN cord-006870-f5w6fw6q 2622 6 was be VBD cord-006870-f5w6fw6q 2622 7 defined define VBN cord-006870-f5w6fw6q 2622 8 when when WRB cord-006870-f5w6fw6q 2622 9 a a DT cord-006870-f5w6fw6q 2622 10 patient patient NN cord-006870-f5w6fw6q 2622 11 met meet VBD cord-006870-f5w6fw6q 2622 12 one one CD cord-006870-f5w6fw6q 2622 13 of of IN cord-006870-f5w6fw6q 2622 14 following follow VBG cord-006870-f5w6fw6q 2622 15 criteria criterion NNS cord-006870-f5w6fw6q 2622 16 : : : cord-006870-f5w6fw6q 2622 17 1 1 LS cord-006870-f5w6fw6q 2622 18 ) ) -RRB- cord-006870-f5w6fw6q 2622 19 required require VBN cord-006870-f5w6fw6q 2622 20 sedation sedation NN cord-006870-f5w6fw6q 2622 21 for for IN cord-006870-f5w6fw6q 2622 22 MRI MRI NNP cord-006870-f5w6fw6q 2622 23 examination examination NN cord-006870-f5w6fw6q 2622 24 due due IN cord-006870-f5w6fw6q 2622 25 to to IN cord-006870-f5w6fw6q 2622 26 irritability irritability NN cord-006870-f5w6fw6q 2622 27 40 40 CD cord-006870-f5w6fw6q 2622 28 mmHg mmHg NNS cord-006870-f5w6fw6q 2622 29 or or CC cord-006870-f5w6fw6q 2622 30 required require VBD cord-006870-f5w6fw6q 2622 31 inotropic inotropic NNP cord-006870-f5w6fw6q 2622 32 agents agent NNS cord-006870-f5w6fw6q 2622 33 , , , cord-006870-f5w6fw6q 2622 34 4 4 CD cord-006870-f5w6fw6q 2622 35 ) ) -RRB- cord-006870-f5w6fw6q 2622 36 developed develop VBN cord-006870-f5w6fw6q 2622 37 cardiac cardiac JJ cord-006870-f5w6fw6q 2622 38 or or CC cord-006870-f5w6fw6q 2622 39 respiratory respiratory JJ cord-006870-f5w6fw6q 2622 40 arrest arrest NN cord-006870-f5w6fw6q 2622 41 . . . cord-006870-f5w6fw6q 2623 1 Of of IN cord-006870-f5w6fw6q 2623 2 218 218 CD cord-006870-f5w6fw6q 2623 3 patients patient NNS cord-006870-f5w6fw6q 2623 4 , , , cord-006870-f5w6fw6q 2623 5 66 66 CD cord-006870-f5w6fw6q 2623 6 ( ( -LRB- cord-006870-f5w6fw6q 2623 7 30.3 30.3 CD cord-006870-f5w6fw6q 2623 8 % % NN cord-006870-f5w6fw6q 2623 9 ) ) -RRB- cord-006870-f5w6fw6q 2623 10 developed develop VBD cord-006870-f5w6fw6q 2623 11 MRI MRI NNP cord-006870-f5w6fw6q 2623 12 - - HYPH cord-006870-f5w6fw6q 2623 13 c c NNP cord-006870-f5w6fw6q 2623 14 . . . cord-006870-f5w6fw6q 2624 1 The the DT cord-006870-f5w6fw6q 2624 2 most most RBS cord-006870-f5w6fw6q 2624 3 common common JJ cord-006870-f5w6fw6q 2624 4 cause cause NN cord-006870-f5w6fw6q 2624 5 of of IN cord-006870-f5w6fw6q 2624 6 MRI MRI NNP cord-006870-f5w6fw6q 2624 7 - - HYPH cord-006870-f5w6fw6q 2624 8 c c NNP cord-006870-f5w6fw6q 2624 9 was be VBD cord-006870-f5w6fw6q 2624 10 unexpected unexpected JJ cord-006870-f5w6fw6q 2624 11 irritability irritability NN cord-006870-f5w6fw6q 2624 12 at at IN cord-006870-f5w6fw6q 2624 13 the the DT cord-006870-f5w6fw6q 2624 14 MRI MRI NNP cord-006870-f5w6fw6q 2624 15 room room NN cord-006870-f5w6fw6q 2624 16 . . . cord-006870-f5w6fw6q 2625 1 Among among IN cord-006870-f5w6fw6q 2625 2 patients patient NNS cord-006870-f5w6fw6q 2625 3 with with IN cord-006870-f5w6fw6q 2625 4 MRI MRI NNP cord-006870-f5w6fw6q 2625 5 - - HYPH cord-006870-f5w6fw6q 2625 6 c c NNP cord-006870-f5w6fw6q 2625 7 , , , cord-006870-f5w6fw6q 2625 8 62 62 CD cord-006870-f5w6fw6q 2625 9 ( ( -LRB- cord-006870-f5w6fw6q 2625 10 93.9 93.9 CD cord-006870-f5w6fw6q 2625 11 % % NN cord-006870-f5w6fw6q 2625 12 ) ) -RRB- cord-006870-f5w6fw6q 2625 13 patients patient NNS cord-006870-f5w6fw6q 2625 14 required require VBD cord-006870-f5w6fw6q 2625 15 unplanned unplanned JJ cord-006870-f5w6fw6q 2625 16 sedation sedation NN cord-006870-f5w6fw6q 2625 17 ; ; : cord-006870-f5w6fw6q 2625 18 9 9 CD cord-006870-f5w6fw6q 2625 19 , , , cord-006870-f5w6fw6q 2625 20 desaturation desaturation NN cord-006870-f5w6fw6q 2625 21 ; ; : cord-006870-f5w6fw6q 2625 22 6 6 CD cord-006870-f5w6fw6q 2625 23 , , , cord-006870-f5w6fw6q 2625 24 hypotension hypotension NN cord-006870-f5w6fw6q 2625 25 ; ; : cord-006870-f5w6fw6q 2625 26 none none NN cord-006870-f5w6fw6q 2625 27 , , , cord-006870-f5w6fw6q 2625 28 cardiac cardiac NN cord-006870-f5w6fw6q 2625 29 or or CC cord-006870-f5w6fw6q 2625 30 respiratory respiratory JJ cord-006870-f5w6fw6q 2625 31 arrest arrest NN cord-006870-f5w6fw6q 2625 32 . . . cord-006870-f5w6fw6q 2626 1 Higher high JJR cord-006870-f5w6fw6q 2626 2 APACHE APACHE NNP cord-006870-f5w6fw6q 2626 3 II ii CD cord-006870-f5w6fw6q 2626 4 scores score NNS cord-006870-f5w6fw6q 2626 5 ( ( -LRB- cord-006870-f5w6fw6q 2626 6 p p NN cord-006870-f5w6fw6q 2626 7 = = SYM cord-006870-f5w6fw6q 2626 8 0.031 0.031 CD cord-006870-f5w6fw6q 2626 9 ) ) -RRB- cord-006870-f5w6fw6q 2626 10 and and CC cord-006870-f5w6fw6q 2626 11 lower low JJR cord-006870-f5w6fw6q 2626 12 GCS GCS NNP cord-006870-f5w6fw6q 2626 13 scores score NNS cord-006870-f5w6fw6q 2626 14 ( ( -LRB- cord-006870-f5w6fw6q 2626 15 p p NN cord-006870-f5w6fw6q 2626 16 = = SYM cord-006870-f5w6fw6q 2626 17 0.047 0.047 CD cord-006870-f5w6fw6q 2626 18 ) ) -RRB- cord-006870-f5w6fw6q 2626 19 on on IN cord-006870-f5w6fw6q 2626 20 admission admission NN cord-006870-f5w6fw6q 2626 21 and and CC cord-006870-f5w6fw6q 2626 22 use use NN cord-006870-f5w6fw6q 2626 23 of of IN cord-006870-f5w6fw6q 2626 24 sedative sedative JJ cord-006870-f5w6fw6q 2626 25 agents agent NNS cord-006870-f5w6fw6q 2626 26 during during IN cord-006870-f5w6fw6q 2626 27 critical critical JJ cord-006870-f5w6fw6q 2626 28 care care NN cord-006870-f5w6fw6q 2626 29 in in IN cord-006870-f5w6fw6q 2626 30 the the DT cord-006870-f5w6fw6q 2626 31 NICU NICU NNP cord-006870-f5w6fw6q 2626 32 were be VBD cord-006870-f5w6fw6q 2626 33 associated associate VBN cord-006870-f5w6fw6q 2626 34 with with IN cord-006870-f5w6fw6q 2626 35 MRI MRI NNP cord-006870-f5w6fw6q 2626 36 - - HYPH cord-006870-f5w6fw6q 2626 37 c c NNP cord-006870-f5w6fw6q 2626 38 ( ( -LRB- cord-006870-f5w6fw6q 2626 39 p p NN cord-006870-f5w6fw6q 2626 40 < < XX cord-006870-f5w6fw6q 2626 41 0.01 0.01 CD cord-006870-f5w6fw6q 2626 42 ) ) -RRB- cord-006870-f5w6fw6q 2626 43 . . . cord-006870-f5w6fw6q 2627 1 In in IN cord-006870-f5w6fw6q 2627 2 addition addition NN cord-006870-f5w6fw6q 2627 3 , , , cord-006870-f5w6fw6q 2627 4 patients patient NNS cord-006870-f5w6fw6q 2627 5 with with IN cord-006870-f5w6fw6q 2627 6 MRI MRI NNP cord-006870-f5w6fw6q 2627 7 - - HYPH cord-006870-f5w6fw6q 2627 8 c c NNP cord-006870-f5w6fw6q 2627 9 had have VBD cord-006870-f5w6fw6q 2627 10 longer long JJR cord-006870-f5w6fw6q 2627 11 MRI MRI NNP cord-006870-f5w6fw6q 2627 12 scan scan JJ cord-006870-f5w6fw6q 2627 13 time time NN cord-006870-f5w6fw6q 2627 14 than than IN cord-006870-f5w6fw6q 2627 15 those those DT cord-006870-f5w6fw6q 2627 16 without without IN cord-006870-f5w6fw6q 2627 17 MRI MRI NNP cord-006870-f5w6fw6q 2627 18 - - HYPH cord-006870-f5w6fw6q 2627 19 c c NNP cord-006870-f5w6fw6q 2627 20 ( ( -LRB- cord-006870-f5w6fw6q 2627 21 p p NN cord-006870-f5w6fw6q 2627 22 = = SYM cord-006870-f5w6fw6q 2627 23 0.004 0.004 CD cord-006870-f5w6fw6q 2627 24 ) ) -RRB- cord-006870-f5w6fw6q 2627 25 . . . cord-006870-f5w6fw6q 2628 1 Many many JJ cord-006870-f5w6fw6q 2628 2 of of IN cord-006870-f5w6fw6q 2628 3 neuro neuro NNP cord-006870-f5w6fw6q 2628 4 - - : cord-006870-f5w6fw6q 2628 5 critically critically RB cord-006870-f5w6fw6q 2628 6 ill ill JJ cord-006870-f5w6fw6q 2628 7 patients patient NNS cord-006870-f5w6fw6q 2628 8 undergo undergo VBP cord-006870-f5w6fw6q 2628 9 unsafe unsafe JJ cord-006870-f5w6fw6q 2628 10 MRI MRI NNP cord-006870-f5w6fw6q 2628 11 scans scan NNS cord-006870-f5w6fw6q 2628 12 . . . cord-006870-f5w6fw6q 2629 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2629 2 findings finding NNS cord-006870-f5w6fw6q 2629 3 suggest suggest VBP cord-006870-f5w6fw6q 2629 4 that that IN cord-006870-f5w6fw6q 2629 5 severity severity NN cord-006870-f5w6fw6q 2629 6 of of IN cord-006870-f5w6fw6q 2629 7 illness illness NN cord-006870-f5w6fw6q 2629 8 and and CC cord-006870-f5w6fw6q 2629 9 use use NN cord-006870-f5w6fw6q 2629 10 of of IN cord-006870-f5w6fw6q 2629 11 sedative sedative JJ cord-006870-f5w6fw6q 2629 12 agents agent NNS cord-006870-f5w6fw6q 2629 13 during during IN cord-006870-f5w6fw6q 2629 14 management management NN cord-006870-f5w6fw6q 2629 15 in in IN cord-006870-f5w6fw6q 2629 16 the the DT cord-006870-f5w6fw6q 2629 17 NICU NICU NNP cord-006870-f5w6fw6q 2629 18 were be VBD cord-006870-f5w6fw6q 2629 19 factors factor NNS cord-006870-f5w6fw6q 2629 20 related relate VBN cord-006870-f5w6fw6q 2629 21 to to IN cord-006870-f5w6fw6q 2629 22 MRI MRI NNP cord-006870-f5w6fw6q 2629 23 - - HYPH cord-006870-f5w6fw6q 2629 24 c c NNP cord-006870-f5w6fw6q 2629 25 . . . cord-006870-f5w6fw6q 2630 1 Introduction introduction NN cord-006870-f5w6fw6q 2630 2 : : : cord-006870-f5w6fw6q 2631 1 Fulminant fulminant JJ cord-006870-f5w6fw6q 2631 2 hepatic hepatic JJ cord-006870-f5w6fw6q 2631 3 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 2631 4 ( ( -LRB- cord-006870-f5w6fw6q 2631 5 FHE FHE NNP cord-006870-f5w6fw6q 2631 6 ) ) -RRB- cord-006870-f5w6fw6q 2631 7 with with IN cord-006870-f5w6fw6q 2631 8 diffuse diffuse JJ cord-006870-f5w6fw6q 2631 9 cerebral cerebral JJ cord-006870-f5w6fw6q 2631 10 edema edema NN cord-006870-f5w6fw6q 2631 11 has have VBZ cord-006870-f5w6fw6q 2631 12 dismal dismal JJ cord-006870-f5w6fw6q 2631 13 prognosis prognosis NN cord-006870-f5w6fw6q 2631 14 if if IN cord-006870-f5w6fw6q 2631 15 transplantation transplantation NN cord-006870-f5w6fw6q 2631 16 is be VBZ cord-006870-f5w6fw6q 2631 17 not not RB cord-006870-f5w6fw6q 2631 18 performed perform VBN cord-006870-f5w6fw6q 2631 19 . . . cord-006870-f5w6fw6q 2632 1 Novel novel JJ cord-006870-f5w6fw6q 2632 2 therapeutic therapeutic JJ cord-006870-f5w6fw6q 2632 3 interventions intervention NNS cord-006870-f5w6fw6q 2632 4 may may MD cord-006870-f5w6fw6q 2632 5 change change VB cord-006870-f5w6fw6q 2632 6 this this DT cord-006870-f5w6fw6q 2632 7 outcome outcome NN cord-006870-f5w6fw6q 2632 8 . . . cord-006870-f5w6fw6q 2633 1 We -PRON- PRP cord-006870-f5w6fw6q 2633 2 reviewed review VBD cord-006870-f5w6fw6q 2633 3 all all DT cord-006870-f5w6fw6q 2633 4 cases case NNS cord-006870-f5w6fw6q 2633 5 with with IN cord-006870-f5w6fw6q 2633 6 FHE FHE NNP cord-006870-f5w6fw6q 2633 7 admitted admit VBN cord-006870-f5w6fw6q 2633 8 to to IN cord-006870-f5w6fw6q 2633 9 our -PRON- PRP$ cord-006870-f5w6fw6q 2633 10 hospital hospital NN cord-006870-f5w6fw6q 2633 11 since since IN cord-006870-f5w6fw6q 2633 12 2008 2008 CD cord-006870-f5w6fw6q 2633 13 . . . cord-006870-f5w6fw6q 2634 1 In in IN cord-006870-f5w6fw6q 2634 2 2010 2010 CD cord-006870-f5w6fw6q 2634 3 , , , cord-006870-f5w6fw6q 2634 4 we -PRON- PRP cord-006870-f5w6fw6q 2634 5 developed develop VBD cord-006870-f5w6fw6q 2634 6 a a DT cord-006870-f5w6fw6q 2634 7 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 2634 8 management management NN cord-006870-f5w6fw6q 2634 9 protocol protocol NN cord-006870-f5w6fw6q 2634 10 , , , cord-006870-f5w6fw6q 2634 11 mandating mandate VBG cord-006870-f5w6fw6q 2634 12 transfer transfer NN cord-006870-f5w6fw6q 2634 13 of of IN cord-006870-f5w6fw6q 2634 14 patients patient NNS cord-006870-f5w6fw6q 2634 15 entering enter VBG cord-006870-f5w6fw6q 2634 16 grade grade NN cord-006870-f5w6fw6q 2634 17 3 3 CD cord-006870-f5w6fw6q 2634 18 from from IN cord-006870-f5w6fw6q 2634 19 other other JJ cord-006870-f5w6fw6q 2634 20 ICUs icu NNS cord-006870-f5w6fw6q 2634 21 to to IN cord-006870-f5w6fw6q 2634 22 the the DT cord-006870-f5w6fw6q 2634 23 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 2634 24 - - HYPH cord-006870-f5w6fw6q 2634 25 ICU ICU NNP cord-006870-f5w6fw6q 2634 26 ( ( -LRB- cord-006870-f5w6fw6q 2634 27 NICU NICU NNP cord-006870-f5w6fw6q 2634 28 ) ) -RRB- cord-006870-f5w6fw6q 2634 29 for for IN cord-006870-f5w6fw6q 2634 30 intracranial intracranial JJ cord-006870-f5w6fw6q 2634 31 pressure pressure NN cord-006870-f5w6fw6q 2634 32 ( ( -LRB- cord-006870-f5w6fw6q 2634 33 ICP ICP NNP cord-006870-f5w6fw6q 2634 34 ) ) -RRB- cord-006870-f5w6fw6q 2634 35 management management NN cord-006870-f5w6fw6q 2634 36 . . . cord-006870-f5w6fw6q 2635 1 Multiple multiple JJ cord-006870-f5w6fw6q 2635 2 interventions intervention NNS cord-006870-f5w6fw6q 2635 3 were be VBD cord-006870-f5w6fw6q 2635 4 utilized utilize VBN cord-006870-f5w6fw6q 2635 5 including include VBG cord-006870-f5w6fw6q 2635 6 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 2635 7 reversal reversal NN cord-006870-f5w6fw6q 2635 8 with with IN cord-006870-f5w6fw6q 2635 9 Factor Factor NNP cord-006870-f5w6fw6q 2635 10 VII VII NNP cord-006870-f5w6fw6q 2635 11 and and CC cord-006870-f5w6fw6q 2635 12 prothrombin prothrombin NN cord-006870-f5w6fw6q 2635 13 complex complex NN cord-006870-f5w6fw6q 2635 14 concentrate concentrate NN cord-006870-f5w6fw6q 2635 15 ( ( -LRB- cord-006870-f5w6fw6q 2635 16 PCC PCC NNP cord-006870-f5w6fw6q 2635 17 , , , cord-006870-f5w6fw6q 2635 18 Kcentra Kcentra NNP cord-006870-f5w6fw6q 2635 19 ) ) -RRB- cord-006870-f5w6fw6q 2635 20 , , , cord-006870-f5w6fw6q 2635 21 ICP ICP NNP cord-006870-f5w6fw6q 2635 22 device device NN cord-006870-f5w6fw6q 2635 23 placement placement NN cord-006870-f5w6fw6q 2635 24 , , , cord-006870-f5w6fw6q 2635 25 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 2635 26 , , , cord-006870-f5w6fw6q 2635 27 aggressive aggressive JJ cord-006870-f5w6fw6q 2635 28 ammonia ammonia NN cord-006870-f5w6fw6q 2635 29 lowering lower VBG cord-006870-f5w6fw6q 2635 30 regimen regimen NN cord-006870-f5w6fw6q 2635 31 with with IN cord-006870-f5w6fw6q 2635 32 lactulose lactulose NN cord-006870-f5w6fw6q 2635 33 and and CC cord-006870-f5w6fw6q 2635 34 rifaximin rifaximin NNP cord-006870-f5w6fw6q 2635 35 , , , cord-006870-f5w6fw6q 2635 36 early early JJ cord-006870-f5w6fw6q 2635 37 renal renal JJ cord-006870-f5w6fw6q 2635 38 replacement replacement NN cord-006870-f5w6fw6q 2635 39 therapy therapy NN cord-006870-f5w6fw6q 2635 40 , , , cord-006870-f5w6fw6q 2635 41 mild mild JJ cord-006870-f5w6fw6q 2635 42 hypothermia hypothermia NN cord-006870-f5w6fw6q 2635 43 for for IN cord-006870-f5w6fw6q 2635 44 refractory refractory JJ cord-006870-f5w6fw6q 2635 45 ICP ICP NNP cord-006870-f5w6fw6q 2635 46 , , , cord-006870-f5w6fw6q 2635 47 in in IN cord-006870-f5w6fw6q 2635 48 conjunction conjunction NN cord-006870-f5w6fw6q 2635 49 with with IN cord-006870-f5w6fw6q 2635 50 liver liver NN cord-006870-f5w6fw6q 2635 51 transplantation transplantation NN cord-006870-f5w6fw6q 2635 52 candidacy candidacy NN cord-006870-f5w6fw6q 2635 53 investigation investigation NN cord-006870-f5w6fw6q 2635 54 . . . cord-006870-f5w6fw6q 2636 1 Results result NNS cord-006870-f5w6fw6q 2636 2 : : : cord-006870-f5w6fw6q 2637 1 Twenty twenty CD cord-006870-f5w6fw6q 2637 2 - - HYPH cord-006870-f5w6fw6q 2637 3 four four CD cord-006870-f5w6fw6q 2637 4 patients patient NNS cord-006870-f5w6fw6q 2637 5 ( ( -LRB- cord-006870-f5w6fw6q 2637 6 19 19 CD cord-006870-f5w6fw6q 2637 7 women woman NNS cord-006870-f5w6fw6q 2637 8 , , , cord-006870-f5w6fw6q 2637 9 mean mean VB cord-006870-f5w6fw6q 2637 10 age age NN cord-006870-f5w6fw6q 2637 11 of of IN cord-006870-f5w6fw6q 2637 12 all all DT cord-006870-f5w6fw6q 2637 13 patients patient NNS cord-006870-f5w6fw6q 2637 14 40 40 CD cord-006870-f5w6fw6q 2637 15 years year NNS cord-006870-f5w6fw6q 2637 16 ) ) -RRB- cord-006870-f5w6fw6q 2637 17 were be VBD cord-006870-f5w6fw6q 2637 18 admitted admit VBN cord-006870-f5w6fw6q 2637 19 ; ; : cord-006870-f5w6fw6q 2637 20 seven seven CD cord-006870-f5w6fw6q 2637 21 were be VBD cord-006870-f5w6fw6q 2637 22 managed manage VBN cord-006870-f5w6fw6q 2637 23 in in IN cord-006870-f5w6fw6q 2637 24 the the DT cord-006870-f5w6fw6q 2637 25 MICU MICU NNP cord-006870-f5w6fw6q 2637 26 / / SYM cord-006870-f5w6fw6q 2637 27 SICU SICU NNP cord-006870-f5w6fw6q 2637 28 and and CC cord-006870-f5w6fw6q 2637 29 17 17 CD cord-006870-f5w6fw6q 2637 30 in in IN cord-006870-f5w6fw6q 2637 31 the the DT cord-006870-f5w6fw6q 2637 32 NICU NICU NNP cord-006870-f5w6fw6q 2637 33 . . . cord-006870-f5w6fw6q 2638 1 The the DT cord-006870-f5w6fw6q 2638 2 etiology etiology NN cord-006870-f5w6fw6q 2638 3 of of IN cord-006870-f5w6fw6q 2638 4 FHE FHE NNP cord-006870-f5w6fw6q 2638 5 was be VBD cord-006870-f5w6fw6q 2638 6 acetaminophen acetaminophen JJ cord-006870-f5w6fw6q 2638 7 toxicity toxicity NN cord-006870-f5w6fw6q 2638 8 in in IN cord-006870-f5w6fw6q 2638 9 72 72 CD cord-006870-f5w6fw6q 2638 10 % % NN cord-006870-f5w6fw6q 2638 11 of of IN cord-006870-f5w6fw6q 2638 12 patients patient NNS cord-006870-f5w6fw6q 2638 13 . . . cord-006870-f5w6fw6q 2639 1 The the DT cord-006870-f5w6fw6q 2639 2 Model Model NNP cord-006870-f5w6fw6q 2639 3 for for IN cord-006870-f5w6fw6q 2639 4 End end NN cord-006870-f5w6fw6q 2639 5 - - HYPH cord-006870-f5w6fw6q 2639 6 Stage stage NN cord-006870-f5w6fw6q 2639 7 Liver liver NN cord-006870-f5w6fw6q 2639 8 Disease Disease NNP cord-006870-f5w6fw6q 2639 9 ( ( -LRB- cord-006870-f5w6fw6q 2639 10 MELD meld VB cord-006870-f5w6fw6q 2639 11 ) ) -RRB- cord-006870-f5w6fw6q 2639 12 admission admission NN cord-006870-f5w6fw6q 2639 13 scores score NNS cord-006870-f5w6fw6q 2639 14 and and CC cord-006870-f5w6fw6q 2639 15 liver liver NN cord-006870-f5w6fw6q 2639 16 enzymes enzyme NNS cord-006870-f5w6fw6q 2639 17 between between IN cord-006870-f5w6fw6q 2639 18 the the DT cord-006870-f5w6fw6q 2639 19 MICU MICU NNP cord-006870-f5w6fw6q 2639 20 / / SYM cord-006870-f5w6fw6q 2639 21 SICU SICU NNP cord-006870-f5w6fw6q 2639 22 and and CC cord-006870-f5w6fw6q 2639 23 the the DT cord-006870-f5w6fw6q 2639 24 NICU NICU NNP cord-006870-f5w6fw6q 2639 25 were be VBD cord-006870-f5w6fw6q 2639 26 not not RB cord-006870-f5w6fw6q 2639 27 different different JJ cord-006870-f5w6fw6q 2640 1 ( ( -LRB- cord-006870-f5w6fw6q 2640 2 Mann Mann NNP cord-006870-f5w6fw6q 2640 3 - - HYPH cord-006870-f5w6fw6q 2640 4 Whitney Whitney NNP cord-006870-f5w6fw6q 2640 5 test test NN cord-006870-f5w6fw6q 2640 6 ) ) -RRB- cord-006870-f5w6fw6q 2640 7 . . . cord-006870-f5w6fw6q 2641 1 Although although IN cord-006870-f5w6fw6q 2641 2 the the DT cord-006870-f5w6fw6q 2641 3 NICU NICU NNP cord-006870-f5w6fw6q 2641 4 admission admission NN cord-006870-f5w6fw6q 2641 5 ammonia ammonia NN cord-006870-f5w6fw6q 2641 6 level level NN cord-006870-f5w6fw6q 2641 7 was be VBD cord-006870-f5w6fw6q 2641 8 higher high JJR cord-006870-f5w6fw6q 2641 9 than than IN cord-006870-f5w6fw6q 2641 10 the the DT cord-006870-f5w6fw6q 2641 11 MICU MICU NNP cord-006870-f5w6fw6q 2641 12 / / SYM cord-006870-f5w6fw6q 2641 13 SICU SICU NNP cord-006870-f5w6fw6q 2641 14 ( ( -LRB- cord-006870-f5w6fw6q 2641 15 168.75 168.75 CD cord-006870-f5w6fw6q 2641 16 vs vs IN cord-006870-f5w6fw6q 2641 17 99.50 99.50 CD cord-006870-f5w6fw6q 2641 18 , , , cord-006870-f5w6fw6q 2641 19 p p NN cord-006870-f5w6fw6q 2641 20 = = SYM cord-006870-f5w6fw6q 2641 21 0.00 0.00 CD cord-006870-f5w6fw6q 2641 22 ) ) -RRB- cord-006870-f5w6fw6q 2641 23 , , , cord-006870-f5w6fw6q 2641 24 the the DT cord-006870-f5w6fw6q 2641 25 lowest low JJS cord-006870-f5w6fw6q 2641 26 achieved achieve VBN cord-006870-f5w6fw6q 2641 27 ammonia ammonia NN cord-006870-f5w6fw6q 2641 28 was be VBD cord-006870-f5w6fw6q 2641 29 lower low JJR cord-006870-f5w6fw6q 2641 30 in in IN cord-006870-f5w6fw6q 2641 31 the the DT cord-006870-f5w6fw6q 2641 32 NICU NICU NNP cord-006870-f5w6fw6q 2641 33 ( ( -LRB- cord-006870-f5w6fw6q 2641 34 41.31 41.31 CD cord-006870-f5w6fw6q 2641 35 vs vs IN cord-006870-f5w6fw6q 2641 36 78.13 78.13 CD cord-006870-f5w6fw6q 2641 37 , , , cord-006870-f5w6fw6q 2641 38 p p NN cord-006870-f5w6fw6q 2641 39 = = SYM cord-006870-f5w6fw6q 2641 40 0.022 0.022 CD cord-006870-f5w6fw6q 2641 41 , , , cord-006870-f5w6fw6q 2641 42 Mann Mann NNP cord-006870-f5w6fw6q 2641 43 - - HYPH cord-006870-f5w6fw6q 2641 44 Whitney Whitney NNP cord-006870-f5w6fw6q 2641 45 ) ) -RRB- cord-006870-f5w6fw6q 2641 46 . . . cord-006870-f5w6fw6q 2642 1 Patients patient NNS cord-006870-f5w6fw6q 2642 2 received receive VBD cord-006870-f5w6fw6q 2642 3 ICP ICP NNP cord-006870-f5w6fw6q 2642 4 monitoring monitoring NN cord-006870-f5w6fw6q 2642 5 ( ( -LRB- cord-006870-f5w6fw6q 2642 6 all all DT cord-006870-f5w6fw6q 2642 7 in in IN cord-006870-f5w6fw6q 2642 8 the the DT cord-006870-f5w6fw6q 2642 9 NICU NICU NNP cord-006870-f5w6fw6q 2642 10 plus plus CC cord-006870-f5w6fw6q 2642 11 2 2 CD cord-006870-f5w6fw6q 2642 12 in in IN cord-006870-f5w6fw6q 2642 13 the the DT cord-006870-f5w6fw6q 2642 14 SICU SICU NNP cord-006870-f5w6fw6q 2642 15 ) ) -RRB- cord-006870-f5w6fw6q 2642 16 and and CC cord-006870-f5w6fw6q 2642 17 the the DT cord-006870-f5w6fw6q 2642 18 highest high JJS cord-006870-f5w6fw6q 2642 19 ICP ICP NNP cord-006870-f5w6fw6q 2642 20 recorded record VBN cord-006870-f5w6fw6q 2642 21 was be VBD cord-006870-f5w6fw6q 2642 22 120 120 CD cord-006870-f5w6fw6q 2642 23 mm mm CD cord-006870-f5w6fw6q 2642 24 Hg Hg NNS cord-006870-f5w6fw6q 2642 25 . . . cord-006870-f5w6fw6q 2643 1 The the DT cord-006870-f5w6fw6q 2643 2 preand preand JJ cord-006870-f5w6fw6q 2643 3 post post JJ cord-006870-f5w6fw6q 2643 4 - - JJ cord-006870-f5w6fw6q 2643 5 coagulation coagulation JJ cord-006870-f5w6fw6q 2643 6 reversal reversal NN cord-006870-f5w6fw6q 2643 7 INR INR NNP cord-006870-f5w6fw6q 2643 8 were be VBD cord-006870-f5w6fw6q 2643 9 3.37 3.37 CD cord-006870-f5w6fw6q 2643 10 and and CC cord-006870-f5w6fw6q 2643 11 1.3 1.3 CD cord-006870-f5w6fw6q 2643 12 , , , cord-006870-f5w6fw6q 2643 13 p=0.031 p=0.031 NNP cord-006870-f5w6fw6q 2643 14 , , , cord-006870-f5w6fw6q 2643 15 Wilcoxon Wilcoxon NNP cord-006870-f5w6fw6q 2643 16 test test NN cord-006870-f5w6fw6q 2643 17 ) ) -RRB- cord-006870-f5w6fw6q 2643 18 . . . cord-006870-f5w6fw6q 2644 1 Seven seven CD cord-006870-f5w6fw6q 2644 2 patients patient NNS cord-006870-f5w6fw6q 2644 3 in in IN cord-006870-f5w6fw6q 2644 4 the the DT cord-006870-f5w6fw6q 2644 5 NICU NICU NNP cord-006870-f5w6fw6q 2644 6 received receive VBD cord-006870-f5w6fw6q 2644 7 hypothermic hypothermic JJ cord-006870-f5w6fw6q 2644 8 treatment treatment NN cord-006870-f5w6fw6q 2644 9 . . . cord-006870-f5w6fw6q 2645 1 Mortality mortality NN cord-006870-f5w6fw6q 2645 2 in in IN cord-006870-f5w6fw6q 2645 3 the the DT cord-006870-f5w6fw6q 2645 4 MICU MICU NNP cord-006870-f5w6fw6q 2645 5 / / SYM cord-006870-f5w6fw6q 2645 6 SICU SICU NNP cord-006870-f5w6fw6q 2645 7 was be VBD cord-006870-f5w6fw6q 2645 8 85.7 85.7 CD cord-006870-f5w6fw6q 2645 9 % % NN cord-006870-f5w6fw6q 2645 10 ( ( -LRB- cord-006870-f5w6fw6q 2645 11 6/7 6/7 CD cord-006870-f5w6fw6q 2645 12 ) ) -RRB- cord-006870-f5w6fw6q 2645 13 and and CC cord-006870-f5w6fw6q 2645 14 in in IN cord-006870-f5w6fw6q 2645 15 the the DT cord-006870-f5w6fw6q 2645 16 NICU NICU NNP cord-006870-f5w6fw6q 2645 17 41.1 41.1 CD cord-006870-f5w6fw6q 2645 18 % % NN cord-006870-f5w6fw6q 2645 19 ( ( -LRB- cord-006870-f5w6fw6q 2645 20 7/17 7/17 CD cord-006870-f5w6fw6q 2645 21 ) ) -RRB- cord-006870-f5w6fw6q 2645 22 , , , cord-006870-f5w6fw6q 2645 23 p p NN cord-006870-f5w6fw6q 2645 24 = = SYM cord-006870-f5w6fw6q 2645 25 0.13 0.13 CD cord-006870-f5w6fw6q 2646 1 ( ( -LRB- cord-006870-f5w6fw6q 2646 2 chi chi NNP cord-006870-f5w6fw6q 2646 3 square square NNP cord-006870-f5w6fw6q 2646 4 test test NN cord-006870-f5w6fw6q 2646 5 ) ) -RRB- cord-006870-f5w6fw6q 2646 6 . . . cord-006870-f5w6fw6q 2647 1 Conclusion conclusion NN cord-006870-f5w6fw6q 2647 2 : : : cord-006870-f5w6fw6q 2648 1 A a DT cord-006870-f5w6fw6q 2648 2 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 2648 3 approach approach NN cord-006870-f5w6fw6q 2648 4 centered center VBN cord-006870-f5w6fw6q 2648 5 around around IN cord-006870-f5w6fw6q 2648 6 Anti anti JJ cord-006870-f5w6fw6q 2648 7 - - JJ cord-006870-f5w6fw6q 2648 8 cerebral cerebral JJ cord-006870-f5w6fw6q 2648 9 edema edema NN cord-006870-f5w6fw6q 2648 10 protocol protocol NN cord-006870-f5w6fw6q 2648 11 - - HYPH cord-006870-f5w6fw6q 2648 12 driven drive VBN cord-006870-f5w6fw6q 2648 13 management management NN cord-006870-f5w6fw6q 2648 14 based base VBN cord-006870-f5w6fw6q 2648 15 on on IN cord-006870-f5w6fw6q 2648 16 novel novel JJ cord-006870-f5w6fw6q 2648 17 interventions intervention NNS cord-006870-f5w6fw6q 2648 18 may may MD cord-006870-f5w6fw6q 2648 19 improve improve VB cord-006870-f5w6fw6q 2648 20 the the DT cord-006870-f5w6fw6q 2648 21 outcome outcome NN cord-006870-f5w6fw6q 2648 22 of of IN cord-006870-f5w6fw6q 2648 23 patients patient NNS cord-006870-f5w6fw6q 2648 24 with with IN cord-006870-f5w6fw6q 2648 25 FHE FHE NNP cord-006870-f5w6fw6q 2648 26 . . . cord-006870-f5w6fw6q 2649 1 Catheter catheter NN cord-006870-f5w6fw6q 2649 2 - - HYPH cord-006870-f5w6fw6q 2649 3 associated associate VBN cord-006870-f5w6fw6q 2649 4 urinary urinary JJ cord-006870-f5w6fw6q 2649 5 tract tract NN cord-006870-f5w6fw6q 2649 6 infections infection NNS cord-006870-f5w6fw6q 2649 7 ( ( -LRB- cord-006870-f5w6fw6q 2649 8 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2649 9 ) ) -RRB- cord-006870-f5w6fw6q 2649 10 are be VBP cord-006870-f5w6fw6q 2649 11 among among IN cord-006870-f5w6fw6q 2649 12 the the DT cord-006870-f5w6fw6q 2649 13 most most RBS cord-006870-f5w6fw6q 2649 14 common common JJ cord-006870-f5w6fw6q 2649 15 health health NN cord-006870-f5w6fw6q 2649 16 - - HYPH cord-006870-f5w6fw6q 2649 17 care care NN cord-006870-f5w6fw6q 2649 18 associated associate VBN cord-006870-f5w6fw6q 2649 19 infections infection NNS cord-006870-f5w6fw6q 2649 20 ( ( -LRB- cord-006870-f5w6fw6q 2649 21 HCAIs hcai NNS cord-006870-f5w6fw6q 2649 22 ) ) -RRB- cord-006870-f5w6fw6q 2649 23 , , , cord-006870-f5w6fw6q 2649 24 ( ( -LRB- cord-006870-f5w6fw6q 2649 25 Gould Gould NNP cord-006870-f5w6fw6q 2649 26 , , , cord-006870-f5w6fw6q 2649 27 2016 2016 CD cord-006870-f5w6fw6q 2649 28 ) ) -RRB- cord-006870-f5w6fw6q 2649 29 . . . cord-006870-f5w6fw6q 2650 1 Neurological neurological JJ cord-006870-f5w6fw6q 2650 2 patients patient NNS cord-006870-f5w6fw6q 2650 3 in in IN cord-006870-f5w6fw6q 2650 4 the the DT cord-006870-f5w6fw6q 2650 5 critical critical JJ cord-006870-f5w6fw6q 2650 6 care care NN cord-006870-f5w6fw6q 2650 7 setting setting NN cord-006870-f5w6fw6q 2650 8 are be VBP cord-006870-f5w6fw6q 2650 9 particularly particularly RB cord-006870-f5w6fw6q 2650 10 at at IN cord-006870-f5w6fw6q 2650 11 risk risk NN cord-006870-f5w6fw6q 2650 12 for for IN cord-006870-f5w6fw6q 2650 13 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2650 14 due due IN cord-006870-f5w6fw6q 2650 15 to to IN cord-006870-f5w6fw6q 2650 16 cognitive cognitive JJ cord-006870-f5w6fw6q 2650 17 , , , cord-006870-f5w6fw6q 2650 18 motor motor NN cord-006870-f5w6fw6q 2650 19 , , , cord-006870-f5w6fw6q 2650 20 and and CC cord-006870-f5w6fw6q 2650 21 sensory sensory JJ cord-006870-f5w6fw6q 2650 22 deficits deficit NNS cord-006870-f5w6fw6q 2650 23 . . . cord-006870-f5w6fw6q 2651 1 In in IN cord-006870-f5w6fw6q 2651 2 the the DT cord-006870-f5w6fw6q 2651 3 Neuro Neuro NNP cord-006870-f5w6fw6q 2651 4 Intensive Intensive NNP cord-006870-f5w6fw6q 2651 5 Care Care NNP cord-006870-f5w6fw6q 2651 6 Unit Unit NNP cord-006870-f5w6fw6q 2651 7 , , , cord-006870-f5w6fw6q 2651 8 despite despite IN cord-006870-f5w6fw6q 2651 9 following follow VBG cord-006870-f5w6fw6q 2651 10 recommended recommend VBN cord-006870-f5w6fw6q 2651 11 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2651 12 reduction reduction NN cord-006870-f5w6fw6q 2651 13 bundle bundle NN cord-006870-f5w6fw6q 2651 14 guidelines guideline NNS cord-006870-f5w6fw6q 2651 15 , , , cord-006870-f5w6fw6q 2651 16 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2651 17 rates rate NNS cord-006870-f5w6fw6q 2651 18 continued continue VBD cord-006870-f5w6fw6q 2651 19 to to TO cord-006870-f5w6fw6q 2651 20 rise rise VB cord-006870-f5w6fw6q 2651 21 over over IN cord-006870-f5w6fw6q 2651 22 the the DT cord-006870-f5w6fw6q 2651 23 last last JJ cord-006870-f5w6fw6q 2651 24 five five CD cord-006870-f5w6fw6q 2651 25 years year NNS cord-006870-f5w6fw6q 2651 26 with with IN cord-006870-f5w6fw6q 2651 27 rates rate NNS cord-006870-f5w6fw6q 2651 28 reaching reach VBG cord-006870-f5w6fw6q 2651 29 6.45 6.45 CD cord-006870-f5w6fw6q 2651 30 per per IN cord-006870-f5w6fw6q 2651 31 1000 1000 CD cord-006870-f5w6fw6q 2651 32 catheter catheter NN cord-006870-f5w6fw6q 2651 33 days day NNS cord-006870-f5w6fw6q 2651 34 . . . cord-006870-f5w6fw6q 2652 1 In in IN cord-006870-f5w6fw6q 2652 2 January January NNP cord-006870-f5w6fw6q 2652 3 of of IN cord-006870-f5w6fw6q 2652 4 2017 2017 CD cord-006870-f5w6fw6q 2652 5 , , , cord-006870-f5w6fw6q 2652 6 the the DT cord-006870-f5w6fw6q 2652 7 unit unit NN cord-006870-f5w6fw6q 2652 8 implemented implement VBD cord-006870-f5w6fw6q 2652 9 a a DT cord-006870-f5w6fw6q 2652 10 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2652 11 Taskforce Taskforce NNP cord-006870-f5w6fw6q 2652 12 to to TO cord-006870-f5w6fw6q 2652 13 perform perform VB cord-006870-f5w6fw6q 2652 14 a a DT cord-006870-f5w6fw6q 2652 15 literature literature NN cord-006870-f5w6fw6q 2652 16 review review NN cord-006870-f5w6fw6q 2652 17 of of IN cord-006870-f5w6fw6q 2652 18 best good JJS cord-006870-f5w6fw6q 2652 19 practices practice NNS cord-006870-f5w6fw6q 2652 20 and and CC cord-006870-f5w6fw6q 2652 21 subsequent subsequent JJ cord-006870-f5w6fw6q 2652 22 1:1 1:1 CD cord-006870-f5w6fw6q 2652 23 peer peer NN cord-006870-f5w6fw6q 2652 24 training training NN cord-006870-f5w6fw6q 2652 25 and and CC cord-006870-f5w6fw6q 2652 26 education education NN cord-006870-f5w6fw6q 2652 27 targeting target VBG cord-006870-f5w6fw6q 2652 28 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2652 29 reduction reduction NN cord-006870-f5w6fw6q 2652 30 . . . cord-006870-f5w6fw6q 2653 1 In in IN cord-006870-f5w6fw6q 2653 2 an an DT cord-006870-f5w6fw6q 2653 3 analysis analysis NN cord-006870-f5w6fw6q 2653 4 of of IN cord-006870-f5w6fw6q 2653 5 organisms organism NNS cord-006870-f5w6fw6q 2653 6 causing cause VBG cord-006870-f5w6fw6q 2653 7 the the DT cord-006870-f5w6fw6q 2653 8 infections infection NNS cord-006870-f5w6fw6q 2653 9 , , , cord-006870-f5w6fw6q 2653 10 E. E. NNP cord-006870-f5w6fw6q 2653 11 coli coli NNS cord-006870-f5w6fw6q 2653 12 and and CC cord-006870-f5w6fw6q 2653 13 Enterococcus Enterococcus NNP cord-006870-f5w6fw6q 2653 14 bacteria bacteria NNS cord-006870-f5w6fw6q 2653 15 accounted account VBD cord-006870-f5w6fw6q 2653 16 for for IN cord-006870-f5w6fw6q 2653 17 more more JJR cord-006870-f5w6fw6q 2653 18 than than IN cord-006870-f5w6fw6q 2653 19 50 50 CD cord-006870-f5w6fw6q 2653 20 % % NN cord-006870-f5w6fw6q 2653 21 of of IN cord-006870-f5w6fw6q 2653 22 CAUTIs cauti NNS cord-006870-f5w6fw6q 2653 23 on on IN cord-006870-f5w6fw6q 2653 24 the the DT cord-006870-f5w6fw6q 2653 25 unit unit NN cord-006870-f5w6fw6q 2653 26 . . . cord-006870-f5w6fw6q 2654 1 The the DT cord-006870-f5w6fw6q 2654 2 taskforce taskforce NN cord-006870-f5w6fw6q 2654 3 ( ( -LRB- cord-006870-f5w6fw6q 2654 4 comprised comprise VBN cord-006870-f5w6fw6q 2654 5 of of IN cord-006870-f5w6fw6q 2654 6 13 13 CD cord-006870-f5w6fw6q 2654 7 staff staff NN cord-006870-f5w6fw6q 2654 8 nurses nurse NNS cord-006870-f5w6fw6q 2654 9 ) ) -RRB- cord-006870-f5w6fw6q 2654 10 focused focus VBD cord-006870-f5w6fw6q 2654 11 on on IN cord-006870-f5w6fw6q 2654 12 fecal fecal JJ cord-006870-f5w6fw6q 2654 13 management management NN cord-006870-f5w6fw6q 2654 14 , , , cord-006870-f5w6fw6q 2654 15 proper proper JJ cord-006870-f5w6fw6q 2654 16 cleaning cleaning NN cord-006870-f5w6fw6q 2654 17 technique technique NN cord-006870-f5w6fw6q 2654 18 , , , cord-006870-f5w6fw6q 2654 19 and and CC cord-006870-f5w6fw6q 2654 20 proper proper JJ cord-006870-f5w6fw6q 2654 21 indications indication NNS cord-006870-f5w6fw6q 2654 22 of of IN cord-006870-f5w6fw6q 2654 23 indwelling indwell VBG cord-006870-f5w6fw6q 2654 24 urinary urinary JJ cord-006870-f5w6fw6q 2654 25 catheter catheter NN cord-006870-f5w6fw6q 2654 26 necessity necessity NN cord-006870-f5w6fw6q 2654 27 . . . cord-006870-f5w6fw6q 2655 1 Using use VBG cord-006870-f5w6fw6q 2655 2 training training NN cord-006870-f5w6fw6q 2655 3 videos video NNS cord-006870-f5w6fw6q 2655 4 , , , cord-006870-f5w6fw6q 2655 5 indwelling indwell VBG cord-006870-f5w6fw6q 2655 6 urinary urinary JJ cord-006870-f5w6fw6q 2655 7 catheter catheter NN cord-006870-f5w6fw6q 2655 8 care care NN cord-006870-f5w6fw6q 2655 9 checklists checklist NNS cord-006870-f5w6fw6q 2655 10 , , , cord-006870-f5w6fw6q 2655 11 and and CC cord-006870-f5w6fw6q 2655 12 real real JJ cord-006870-f5w6fw6q 2655 13 - - HYPH cord-006870-f5w6fw6q 2655 14 time time NN cord-006870-f5w6fw6q 2655 15 feedback feedback NN cord-006870-f5w6fw6q 2655 16 on on IN cord-006870-f5w6fw6q 2655 17 technique technique NN cord-006870-f5w6fw6q 2655 18 , , , cord-006870-f5w6fw6q 2655 19 the the DT cord-006870-f5w6fw6q 2655 20 taskforce taskforce NN cord-006870-f5w6fw6q 2655 21 performed perform VBD cord-006870-f5w6fw6q 2655 22 1:1 1:1 CD cord-006870-f5w6fw6q 2655 23 training training NN cord-006870-f5w6fw6q 2655 24 with with IN cord-006870-f5w6fw6q 2655 25 bedside bedside NN cord-006870-f5w6fw6q 2655 26 staff staff NN cord-006870-f5w6fw6q 2655 27 over over IN cord-006870-f5w6fw6q 2655 28 four four CD cord-006870-f5w6fw6q 2655 29 weeks week NNS cord-006870-f5w6fw6q 2655 30 . . . cord-006870-f5w6fw6q 2656 1 To to TO cord-006870-f5w6fw6q 2656 2 ensure ensure VB cord-006870-f5w6fw6q 2656 3 undivided undivided JJ cord-006870-f5w6fw6q 2656 4 attention attention NN cord-006870-f5w6fw6q 2656 5 , , , cord-006870-f5w6fw6q 2656 6 the the DT cord-006870-f5w6fw6q 2656 7 taskforce taskforce NN cord-006870-f5w6fw6q 2656 8 worked work VBD cord-006870-f5w6fw6q 2656 9 in in IN cord-006870-f5w6fw6q 2656 10 pairs pair NNS cord-006870-f5w6fw6q 2656 11 enabling enable VBG cord-006870-f5w6fw6q 2656 12 one one CD cord-006870-f5w6fw6q 2656 13 trainer trainer NN cord-006870-f5w6fw6q 2656 14 to to TO cord-006870-f5w6fw6q 2656 15 teach teach VB cord-006870-f5w6fw6q 2656 16 and and CC cord-006870-f5w6fw6q 2656 17 observe observe VB cord-006870-f5w6fw6q 2656 18 the the DT cord-006870-f5w6fw6q 2656 19 staff staff NN cord-006870-f5w6fw6q 2656 20 member member NN cord-006870-f5w6fw6q 2656 21 receiving receive VBG cord-006870-f5w6fw6q 2656 22 training training NN cord-006870-f5w6fw6q 2656 23 while while IN cord-006870-f5w6fw6q 2656 24 the the DT cord-006870-f5w6fw6q 2656 25 second second JJ cord-006870-f5w6fw6q 2656 26 trainer trainer NN cord-006870-f5w6fw6q 2656 27 provided provide VBD cord-006870-f5w6fw6q 2656 28 the the DT cord-006870-f5w6fw6q 2656 29 necessary necessary JJ cord-006870-f5w6fw6q 2656 30 clinical clinical JJ cord-006870-f5w6fw6q 2656 31 duties duty NNS cord-006870-f5w6fw6q 2656 32 for for IN cord-006870-f5w6fw6q 2656 33 the the DT cord-006870-f5w6fw6q 2656 34 trainee trainee NN cord-006870-f5w6fw6q 2656 35 's 's POS cord-006870-f5w6fw6q 2656 36 patients patient NNS cord-006870-f5w6fw6q 2656 37 . . . cord-006870-f5w6fw6q 2657 1 After after IN cord-006870-f5w6fw6q 2657 2 implementation implementation NN cord-006870-f5w6fw6q 2657 3 , , , cord-006870-f5w6fw6q 2657 4 the the DT cord-006870-f5w6fw6q 2657 5 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2657 6 rate rate NN cord-006870-f5w6fw6q 2657 7 decreased decrease VBD cord-006870-f5w6fw6q 2657 8 to to IN cord-006870-f5w6fw6q 2657 9 3.43 3.43 CD cord-006870-f5w6fw6q 2657 10 for for IN cord-006870-f5w6fw6q 2657 11 January January NNP cord-006870-f5w6fw6q 2657 12 - - HYPH cord-006870-f5w6fw6q 2657 13 March March NNP cord-006870-f5w6fw6q 2657 14 2017 2017 CD cord-006870-f5w6fw6q 2657 15 and and CC cord-006870-f5w6fw6q 2657 16 2.83 2.83 CD cord-006870-f5w6fw6q 2657 17 for for IN cord-006870-f5w6fw6q 2657 18 April April NNP cord-006870-f5w6fw6q 2657 19 - - HYPH cord-006870-f5w6fw6q 2657 20 June June NNP cord-006870-f5w6fw6q 2657 21 2017 2017 CD cord-006870-f5w6fw6q 2657 22 , , , cord-006870-f5w6fw6q 2657 23 lowering lower VBG cord-006870-f5w6fw6q 2657 24 total total JJ cord-006870-f5w6fw6q 2657 25 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2657 26 events event NNS cord-006870-f5w6fw6q 2657 27 to to IN cord-006870-f5w6fw6q 2657 28 23 23 CD cord-006870-f5w6fw6q 2657 29 for for IN cord-006870-f5w6fw6q 2657 30 FY17 FY17 NNP cord-006870-f5w6fw6q 2657 31 compared compare VBN cord-006870-f5w6fw6q 2657 32 to to IN cord-006870-f5w6fw6q 2657 33 32 32 CD cord-006870-f5w6fw6q 2657 34 for for IN cord-006870-f5w6fw6q 2657 35 FY16 FY16 NNPS cord-006870-f5w6fw6q 2657 36 . . . cord-006870-f5w6fw6q 2658 1 Implementing implement VBG cord-006870-f5w6fw6q 2658 2 a a DT cord-006870-f5w6fw6q 2658 3 1:1 1:1 CD cord-006870-f5w6fw6q 2658 4 training training NN cord-006870-f5w6fw6q 2658 5 program program NN cord-006870-f5w6fw6q 2658 6 focused focus VBN cord-006870-f5w6fw6q 2658 7 on on IN cord-006870-f5w6fw6q 2658 8 fecal fecal JJ cord-006870-f5w6fw6q 2658 9 management management NN cord-006870-f5w6fw6q 2658 10 , , , cord-006870-f5w6fw6q 2658 11 cleaning cleaning NN cord-006870-f5w6fw6q 2658 12 techniques technique NNS cord-006870-f5w6fw6q 2658 13 , , , cord-006870-f5w6fw6q 2658 14 and and CC cord-006870-f5w6fw6q 2658 15 appropriately appropriately RB cord-006870-f5w6fw6q 2658 16 timed timed JJ cord-006870-f5w6fw6q 2658 17 catheter catheter NN cord-006870-f5w6fw6q 2658 18 removal removal NN cord-006870-f5w6fw6q 2658 19 can can MD cord-006870-f5w6fw6q 2658 20 reduce reduce VB cord-006870-f5w6fw6q 2658 21 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2658 22 rates rate NNS cord-006870-f5w6fw6q 2658 23 in in IN cord-006870-f5w6fw6q 2658 24 the the DT cord-006870-f5w6fw6q 2658 25 neuro neuro NNP cord-006870-f5w6fw6q 2658 26 critical critical JJ cord-006870-f5w6fw6q 2658 27 care care NN cord-006870-f5w6fw6q 2658 28 setting setting NN cord-006870-f5w6fw6q 2658 29 . . . cord-006870-f5w6fw6q 2659 1 Brain brain NN cord-006870-f5w6fw6q 2659 2 aneurysms aneurysm NNS cord-006870-f5w6fw6q 2659 3 can can MD cord-006870-f5w6fw6q 2659 4 be be VB cord-006870-f5w6fw6q 2659 5 treated treat VBN cord-006870-f5w6fw6q 2659 6 with with IN cord-006870-f5w6fw6q 2659 7 coil coil NN cord-006870-f5w6fw6q 2659 8 embolization embolization NN cord-006870-f5w6fw6q 2659 9 or or CC cord-006870-f5w6fw6q 2659 10 flow flow NN cord-006870-f5w6fw6q 2659 11 - - HYPH cord-006870-f5w6fw6q 2659 12 diverting divert VBG cord-006870-f5w6fw6q 2659 13 devices device NNS cord-006870-f5w6fw6q 2659 14 . . . cord-006870-f5w6fw6q 2660 1 Thromboembolism Thromboembolism NNP cord-006870-f5w6fw6q 2660 2 is be VBZ cord-006870-f5w6fw6q 2660 3 a a DT cord-006870-f5w6fw6q 2660 4 major major JJ cord-006870-f5w6fw6q 2660 5 complication complication NN cord-006870-f5w6fw6q 2660 6 of of IN cord-006870-f5w6fw6q 2660 7 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 2660 8 coil coil NN cord-006870-f5w6fw6q 2660 9 embolization embolization NN cord-006870-f5w6fw6q 2660 10 , , , cord-006870-f5w6fw6q 2660 11 with with IN cord-006870-f5w6fw6q 2660 12 an an DT cord-006870-f5w6fw6q 2660 13 incidence incidence NN cord-006870-f5w6fw6q 2660 14 as as RB cord-006870-f5w6fw6q 2660 15 high high JJ cord-006870-f5w6fw6q 2660 16 as as IN cord-006870-f5w6fw6q 2660 17 28 28 CD cord-006870-f5w6fw6q 2660 18 % % NN cord-006870-f5w6fw6q 2660 19 . . . cord-006870-f5w6fw6q 2661 1 New new JJ cord-006870-f5w6fw6q 2661 2 flowdiverting flowdiverting NN cord-006870-f5w6fw6q 2661 3 devices device NNS cord-006870-f5w6fw6q 2661 4 have have VBP cord-006870-f5w6fw6q 2661 5 been be VBN cord-006870-f5w6fw6q 2661 6 designed design VBN cord-006870-f5w6fw6q 2661 7 to to TO cord-006870-f5w6fw6q 2661 8 have have VB cord-006870-f5w6fw6q 2661 9 a a DT cord-006870-f5w6fw6q 2661 10 mesh mesh NN cord-006870-f5w6fw6q 2661 11 with with IN cord-006870-f5w6fw6q 2661 12 high high JJ cord-006870-f5w6fw6q 2661 13 coverage coverage NN cord-006870-f5w6fw6q 2661 14 area area NN cord-006870-f5w6fw6q 2661 15 and and CC cord-006870-f5w6fw6q 2661 16 high high JJ cord-006870-f5w6fw6q 2661 17 flexibility flexibility NN cord-006870-f5w6fw6q 2661 18 to to TO cord-006870-f5w6fw6q 2661 19 facilitate facilitate VB cord-006870-f5w6fw6q 2661 20 the the DT cord-006870-f5w6fw6q 2661 21 redirection redirection NN cord-006870-f5w6fw6q 2661 22 of of IN cord-006870-f5w6fw6q 2661 23 blood blood NN cord-006870-f5w6fw6q 2661 24 flow flow NN cord-006870-f5w6fw6q 2661 25 . . . cord-006870-f5w6fw6q 2662 1 These these DT cord-006870-f5w6fw6q 2662 2 features feature NNS cord-006870-f5w6fw6q 2662 3 can can MD cord-006870-f5w6fw6q 2662 4 induce induce VB cord-006870-f5w6fw6q 2662 5 blood blood NN cord-006870-f5w6fw6q 2662 6 stagnation stagnation NN cord-006870-f5w6fw6q 2662 7 and and CC cord-006870-f5w6fw6q 2662 8 thrombosis thrombosis NN cord-006870-f5w6fw6q 2662 9 . . . cord-006870-f5w6fw6q 2663 1 To to TO cord-006870-f5w6fw6q 2663 2 reduce reduce VB cord-006870-f5w6fw6q 2663 3 the the DT cord-006870-f5w6fw6q 2663 4 risk risk NN cord-006870-f5w6fw6q 2663 5 of of IN cord-006870-f5w6fw6q 2663 6 thrombosis thrombosis NN cord-006870-f5w6fw6q 2663 7 , , , cord-006870-f5w6fw6q 2663 8 the the DT cord-006870-f5w6fw6q 2663 9 common common JJ cord-006870-f5w6fw6q 2663 10 but but CC cord-006870-f5w6fw6q 2663 11 unproven unproven JJ cord-006870-f5w6fw6q 2663 12 practice practice NN cord-006870-f5w6fw6q 2663 13 of of IN cord-006870-f5w6fw6q 2663 14 dual dual JJ cord-006870-f5w6fw6q 2663 15 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 2663 16 therapy therapy NN cord-006870-f5w6fw6q 2663 17 with with IN cord-006870-f5w6fw6q 2663 18 aspirin aspirin NN cord-006870-f5w6fw6q 2663 19 and and CC cord-006870-f5w6fw6q 2663 20 clopidogrel clopidogrel NN cord-006870-f5w6fw6q 2663 21 has have VBZ cord-006870-f5w6fw6q 2663 22 been be VBN cord-006870-f5w6fw6q 2663 23 implemented implement VBN cord-006870-f5w6fw6q 2663 24 from from IN cord-006870-f5w6fw6q 2663 25 the the DT cord-006870-f5w6fw6q 2663 26 cardiac cardiac JJ cord-006870-f5w6fw6q 2663 27 literature literature NN cord-006870-f5w6fw6q 2663 28 . . . cord-006870-f5w6fw6q 2664 1 Despite despite IN cord-006870-f5w6fw6q 2664 2 some some DT cord-006870-f5w6fw6q 2664 3 favorable favorable JJ cord-006870-f5w6fw6q 2664 4 outcomes outcome NNS cord-006870-f5w6fw6q 2664 5 , , , cord-006870-f5w6fw6q 2664 6 clopidogrel clopidogrel NN cord-006870-f5w6fw6q 2664 7 , , , cord-006870-f5w6fw6q 2664 8 " " `` cord-006870-f5w6fw6q 2664 9 non non JJ cord-006870-f5w6fw6q 2664 10 - - JJ cord-006870-f5w6fw6q 2664 11 responsiveness responsiveness JJ cord-006870-f5w6fw6q 2664 12 " " '' cord-006870-f5w6fw6q 2664 13 has have VBZ cord-006870-f5w6fw6q 2664 14 been be VBN cord-006870-f5w6fw6q 2664 15 reported report VBN cord-006870-f5w6fw6q 2664 16 to to TO cord-006870-f5w6fw6q 2664 17 be be VB cord-006870-f5w6fw6q 2664 18 present present JJ cord-006870-f5w6fw6q 2664 19 in in IN cord-006870-f5w6fw6q 2664 20 as as RB cord-006870-f5w6fw6q 2664 21 low low JJ cord-006870-f5w6fw6q 2664 22 as as IN cord-006870-f5w6fw6q 2664 23 5 5 CD cord-006870-f5w6fw6q 2664 24 % % NN cord-006870-f5w6fw6q 2664 25 to to IN cord-006870-f5w6fw6q 2664 26 as as RB cord-006870-f5w6fw6q 2664 27 high high JJ cord-006870-f5w6fw6q 2664 28 as as IN cord-006870-f5w6fw6q 2664 29 56 56 CD cord-006870-f5w6fw6q 2664 30 % % NN cord-006870-f5w6fw6q 2664 31 making make VBG cord-006870-f5w6fw6q 2664 32 this this DT cord-006870-f5w6fw6q 2664 33 agent agent NN cord-006870-f5w6fw6q 2664 34 not not RB cord-006870-f5w6fw6q 2664 35 optimal optimal JJ cord-006870-f5w6fw6q 2664 36 . . . cord-006870-f5w6fw6q 2665 1 This this DT cord-006870-f5w6fw6q 2665 2 will will MD cord-006870-f5w6fw6q 2665 3 leave leave VB cord-006870-f5w6fw6q 2665 4 practitioners practitioner NNS cord-006870-f5w6fw6q 2665 5 with with IN cord-006870-f5w6fw6q 2665 6 other other JJ cord-006870-f5w6fw6q 2665 7 oral oral JJ cord-006870-f5w6fw6q 2665 8 P2Y12 P2Y12 NNS cord-006870-f5w6fw6q 2665 9 alternatives alternative NNS cord-006870-f5w6fw6q 2665 10 such such JJ cord-006870-f5w6fw6q 2665 11 as as IN cord-006870-f5w6fw6q 2665 12 prasugrel prasugrel NNP cord-006870-f5w6fw6q 2665 13 and and CC cord-006870-f5w6fw6q 2665 14 ticagrelor ticagrelor NNP cord-006870-f5w6fw6q 2665 15 that that WDT cord-006870-f5w6fw6q 2665 16 have have VBP cord-006870-f5w6fw6q 2665 17 not not RB cord-006870-f5w6fw6q 2665 18 been be VBN cord-006870-f5w6fw6q 2665 19 studied study VBN cord-006870-f5w6fw6q 2665 20 widely widely RB cord-006870-f5w6fw6q 2665 21 in in IN cord-006870-f5w6fw6q 2665 22 this this DT cord-006870-f5w6fw6q 2665 23 setting setting NN cord-006870-f5w6fw6q 2665 24 . . . cord-006870-f5w6fw6q 2666 1 It -PRON- PRP cord-006870-f5w6fw6q 2666 2 is be VBZ cord-006870-f5w6fw6q 2666 3 therefore therefore RB cord-006870-f5w6fw6q 2666 4 likely likely JJ cord-006870-f5w6fw6q 2666 5 that that DT cord-006870-f5w6fw6q 2666 6 controversy controversy NN cord-006870-f5w6fw6q 2666 7 exists exist VBZ cord-006870-f5w6fw6q 2666 8 among among IN cord-006870-f5w6fw6q 2666 9 practitioners practitioner NNS cord-006870-f5w6fw6q 2666 10 regarding regard VBG cord-006870-f5w6fw6q 2666 11 the the DT cord-006870-f5w6fw6q 2666 12 use use NN cord-006870-f5w6fw6q 2666 13 of of IN cord-006870-f5w6fw6q 2666 14 optimal optimal JJ cord-006870-f5w6fw6q 2666 15 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 2666 16 agents agent NNS cord-006870-f5w6fw6q 2666 17 in in IN cord-006870-f5w6fw6q 2666 18 neurointerventional neurointerventional JJ cord-006870-f5w6fw6q 2666 19 procedures procedure NNS cord-006870-f5w6fw6q 2666 20 . . . cord-006870-f5w6fw6q 2667 1 We -PRON- PRP cord-006870-f5w6fw6q 2667 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 2667 3 that that IN cord-006870-f5w6fw6q 2667 4 practices practice NNS cord-006870-f5w6fw6q 2667 5 in in IN cord-006870-f5w6fw6q 2667 6 regards regard NNS cord-006870-f5w6fw6q 2667 7 with with IN cord-006870-f5w6fw6q 2667 8 the the DT cord-006870-f5w6fw6q 2667 9 use use NN cord-006870-f5w6fw6q 2667 10 of of IN cord-006870-f5w6fw6q 2667 11 oral oral JJ cord-006870-f5w6fw6q 2667 12 antiplatelets antiplatelet NNS cord-006870-f5w6fw6q 2667 13 in in IN cord-006870-f5w6fw6q 2667 14 neurointerventional neurointerventional JJ cord-006870-f5w6fw6q 2667 15 procedures procedure NNS cord-006870-f5w6fw6q 2667 16 are be VBP cord-006870-f5w6fw6q 2667 17 likely likely RB cord-006870-f5w6fw6q 2667 18 heterogeneous heterogeneous JJ cord-006870-f5w6fw6q 2667 19 and and CC cord-006870-f5w6fw6q 2667 20 different different JJ cord-006870-f5w6fw6q 2667 21 from from IN cord-006870-f5w6fw6q 2667 22 state state NN cord-006870-f5w6fw6q 2667 23 to to IN cord-006870-f5w6fw6q 2667 24 state state NN cord-006870-f5w6fw6q 2667 25 . . . cord-006870-f5w6fw6q 2668 1 By by IN cord-006870-f5w6fw6q 2668 2 using use VBG cord-006870-f5w6fw6q 2668 3 an an DT cord-006870-f5w6fw6q 2668 4 electronic electronic JJ cord-006870-f5w6fw6q 2668 5 survey survey NN cord-006870-f5w6fw6q 2668 6 , , , cord-006870-f5w6fw6q 2668 7 we -PRON- PRP cord-006870-f5w6fw6q 2668 8 would would MD cord-006870-f5w6fw6q 2668 9 like like VB cord-006870-f5w6fw6q 2668 10 to to TO cord-006870-f5w6fw6q 2668 11 identify identify VB cord-006870-f5w6fw6q 2668 12 different different JJ cord-006870-f5w6fw6q 2668 13 practices practice NNS cord-006870-f5w6fw6q 2668 14 surrounding surround VBG cord-006870-f5w6fw6q 2668 15 the the DT cord-006870-f5w6fw6q 2668 16 use use NN cord-006870-f5w6fw6q 2668 17 of of IN cord-006870-f5w6fw6q 2668 18 oral oral JJ cord-006870-f5w6fw6q 2668 19 anti anti NNS cord-006870-f5w6fw6q 2668 20 - - NNS cord-006870-f5w6fw6q 2668 21 platelets platelet NNS cord-006870-f5w6fw6q 2668 22 in in IN cord-006870-f5w6fw6q 2668 23 neuro neuro NNP cord-006870-f5w6fw6q 2668 24 - - HYPH cord-006870-f5w6fw6q 2668 25 endovascular endovascular JJ cord-006870-f5w6fw6q 2668 26 centers center NNS cord-006870-f5w6fw6q 2668 27 in in IN cord-006870-f5w6fw6q 2668 28 the the DT cord-006870-f5w6fw6q 2668 29 United United NNP cord-006870-f5w6fw6q 2668 30 States States NNP cord-006870-f5w6fw6q 2668 31 . . . cord-006870-f5w6fw6q 2669 1 An an DT cord-006870-f5w6fw6q 2669 2 electronic electronic JJ cord-006870-f5w6fw6q 2669 3 survey survey NN cord-006870-f5w6fw6q 2669 4 will will MD cord-006870-f5w6fw6q 2669 5 be be VB cord-006870-f5w6fw6q 2669 6 distributed distribute VBN cord-006870-f5w6fw6q 2669 7 via via IN cord-006870-f5w6fw6q 2669 8 the the DT cord-006870-f5w6fw6q 2669 9 Web web NN cord-006870-f5w6fw6q 2669 10 using use VBG cord-006870-f5w6fw6q 2669 11 Survey Survey NNP cord-006870-f5w6fw6q 2669 12 Monkey Monkey NNP cord-006870-f5w6fw6q 2669 13 ( ( -LRB- cord-006870-f5w6fw6q 2669 14 Seattle Seattle NNP cord-006870-f5w6fw6q 2669 15 , , , cord-006870-f5w6fw6q 2669 16 WA WA NNP cord-006870-f5w6fw6q 2669 17 ) ) -RRB- cord-006870-f5w6fw6q 2669 18 . . . cord-006870-f5w6fw6q 2670 1 The the DT cord-006870-f5w6fw6q 2670 2 survey survey NN cord-006870-f5w6fw6q 2670 3 will will MD cord-006870-f5w6fw6q 2670 4 be be VB cord-006870-f5w6fw6q 2670 5 posted post VBN cord-006870-f5w6fw6q 2670 6 on on IN cord-006870-f5w6fw6q 2670 7 the the DT cord-006870-f5w6fw6q 2670 8 neuro neuro NNP cord-006870-f5w6fw6q 2670 9 - - HYPH cord-006870-f5w6fw6q 2670 10 critical critical JJ cord-006870-f5w6fw6q 2670 11 care care NN cord-006870-f5w6fw6q 2670 12 society society NN cord-006870-f5w6fw6q 2670 13 ( ( -LRB- cord-006870-f5w6fw6q 2670 14 NCS NCS NNP cord-006870-f5w6fw6q 2670 15 ) ) -RRB- cord-006870-f5w6fw6q 2670 16 web web NN cord-006870-f5w6fw6q 2670 17 page page NN cord-006870-f5w6fw6q 2670 18 . . . cord-006870-f5w6fw6q 2671 1 All all DT cord-006870-f5w6fw6q 2671 2 practicing practice VBG cord-006870-f5w6fw6q 2671 3 neuro neuro NNP cord-006870-f5w6fw6q 2671 4 ICU ICU NNP cord-006870-f5w6fw6q 2671 5 or or CC cord-006870-f5w6fw6q 2671 6 stroke stroke NN cord-006870-f5w6fw6q 2671 7 physicians physician NNS cord-006870-f5w6fw6q 2671 8 , , , cord-006870-f5w6fw6q 2671 9 pharmacists pharmacist NNS cord-006870-f5w6fw6q 2671 10 , , , cord-006870-f5w6fw6q 2671 11 physician physician NN cord-006870-f5w6fw6q 2671 12 assistants assistant NNS cord-006870-f5w6fw6q 2671 13 , , , cord-006870-f5w6fw6q 2671 14 or or CC cord-006870-f5w6fw6q 2671 15 nurse nurse NN cord-006870-f5w6fw6q 2671 16 practitioners practitioner NNS cord-006870-f5w6fw6q 2671 17 are be VBP cord-006870-f5w6fw6q 2671 18 eligible eligible JJ cord-006870-f5w6fw6q 2671 19 to to TO cord-006870-f5w6fw6q 2671 20 respond respond VB cord-006870-f5w6fw6q 2671 21 to to IN cord-006870-f5w6fw6q 2671 22 this this DT cord-006870-f5w6fw6q 2671 23 survey survey NN cord-006870-f5w6fw6q 2671 24 . . . cord-006870-f5w6fw6q 2672 1 This this DT cord-006870-f5w6fw6q 2672 2 survey survey NN cord-006870-f5w6fw6q 2672 3 is be VBZ cord-006870-f5w6fw6q 2672 4 approved approve VBN cord-006870-f5w6fw6q 2672 5 by by IN cord-006870-f5w6fw6q 2672 6 the the DT cord-006870-f5w6fw6q 2672 7 Johns Johns NNP cord-006870-f5w6fw6q 2672 8 Hopkins Hopkins NNP cord-006870-f5w6fw6q 2672 9 Hospital Hospital NNP cord-006870-f5w6fw6q 2672 10 IRB IRB NNP cord-006870-f5w6fw6q 2672 11 and and CC cord-006870-f5w6fw6q 2672 12 the the DT cord-006870-f5w6fw6q 2672 13 NCS NCS NNP cord-006870-f5w6fw6q 2672 14 research research NN cord-006870-f5w6fw6q 2672 15 committee committee NN cord-006870-f5w6fw6q 2672 16 . . . cord-006870-f5w6fw6q 2673 1 8 8 CD cord-006870-f5w6fw6q 2673 2 centers center NNS cord-006870-f5w6fw6q 2673 3 have have VBP cord-006870-f5w6fw6q 2673 4 completed complete VBN cord-006870-f5w6fw6q 2673 5 the the DT cord-006870-f5w6fw6q 2673 6 survey survey NN cord-006870-f5w6fw6q 2673 7 at at IN cord-006870-f5w6fw6q 2673 8 this this DT cord-006870-f5w6fw6q 2673 9 point point NN cord-006870-f5w6fw6q 2673 10 . . . cord-006870-f5w6fw6q 2674 1 The the DT cord-006870-f5w6fw6q 2674 2 results result NNS cord-006870-f5w6fw6q 2674 3 will will MD cord-006870-f5w6fw6q 2674 4 be be VB cord-006870-f5w6fw6q 2674 5 analyzed analyze VBN cord-006870-f5w6fw6q 2674 6 after after IN cord-006870-f5w6fw6q 2674 7 the the DT cord-006870-f5w6fw6q 2674 8 closing closing NN cord-006870-f5w6fw6q 2674 9 date date NN cord-006870-f5w6fw6q 2674 10 of of IN cord-006870-f5w6fw6q 2674 11 survey survey NN cord-006870-f5w6fw6q 2674 12 ( ( -LRB- cord-006870-f5w6fw6q 2674 13 9/4/2017 9/4/2017 CD cord-006870-f5w6fw6q 2674 14 ) ) -RRB- cord-006870-f5w6fw6q 2674 15 . . . cord-006870-f5w6fw6q 2675 1 To to TO cord-006870-f5w6fw6q 2675 2 be be VB cord-006870-f5w6fw6q 2675 3 completed complete VBN cord-006870-f5w6fw6q 2676 1 Myasthenia myasthenia NN cord-006870-f5w6fw6q 2676 2 Gravis Gravis NNP cord-006870-f5w6fw6q 2676 3 ( ( -LRB- cord-006870-f5w6fw6q 2676 4 MG MG NNP cord-006870-f5w6fw6q 2676 5 ) ) -RRB- cord-006870-f5w6fw6q 2676 6 Crisis Crisis NNP cord-006870-f5w6fw6q 2676 7 and and CC cord-006870-f5w6fw6q 2676 8 Guillain Guillain NNP cord-006870-f5w6fw6q 2676 9 - - HYPH cord-006870-f5w6fw6q 2676 10 Barre Barre NNP cord-006870-f5w6fw6q 2676 11 Syndrome Syndrome NNP cord-006870-f5w6fw6q 2676 12 ( ( -LRB- cord-006870-f5w6fw6q 2676 13 GBS GBS NNP cord-006870-f5w6fw6q 2676 14 ) ) -RRB- cord-006870-f5w6fw6q 2676 15 are be VBP cord-006870-f5w6fw6q 2676 16 immune immune JJ cord-006870-f5w6fw6q 2676 17 mediated mediate VBN cord-006870-f5w6fw6q 2676 18 diseases disease NNS cord-006870-f5w6fw6q 2676 19 that that WDT cord-006870-f5w6fw6q 2676 20 may may MD cord-006870-f5w6fw6q 2676 21 require require VB cord-006870-f5w6fw6q 2676 22 mechanical mechanical JJ cord-006870-f5w6fw6q 2676 23 ventilation ventilation NN cord-006870-f5w6fw6q 2676 24 as as IN cord-006870-f5w6fw6q 2676 25 part part NN cord-006870-f5w6fw6q 2676 26 of of IN cord-006870-f5w6fw6q 2676 27 their -PRON- PRP$ cord-006870-f5w6fw6q 2676 28 management management NN cord-006870-f5w6fw6q 2676 29 if if IN cord-006870-f5w6fw6q 2676 30 severe severe JJ cord-006870-f5w6fw6q 2676 31 . . . cord-006870-f5w6fw6q 2677 1 Comparative comparative JJ cord-006870-f5w6fw6q 2677 2 analysis analysis NN cord-006870-f5w6fw6q 2677 3 of of IN cord-006870-f5w6fw6q 2677 4 outcomes outcome NNS cord-006870-f5w6fw6q 2677 5 in in IN cord-006870-f5w6fw6q 2677 6 terms term NNS cord-006870-f5w6fw6q 2677 7 of of IN cord-006870-f5w6fw6q 2677 8 length length NN cord-006870-f5w6fw6q 2677 9 of of IN cord-006870-f5w6fw6q 2677 10 stay stay NN cord-006870-f5w6fw6q 2677 11 , , , cord-006870-f5w6fw6q 2677 12 disability disability NN cord-006870-f5w6fw6q 2677 13 , , , cord-006870-f5w6fw6q 2677 14 and and CC cord-006870-f5w6fw6q 2677 15 mortality mortality NN cord-006870-f5w6fw6q 2677 16 between between IN cord-006870-f5w6fw6q 2677 17 these these DT cord-006870-f5w6fw6q 2677 18 two two CD cord-006870-f5w6fw6q 2677 19 disease disease NN cord-006870-f5w6fw6q 2677 20 entities entity NNS cord-006870-f5w6fw6q 2677 21 at at IN cord-006870-f5w6fw6q 2677 22 national national JJ cord-006870-f5w6fw6q 2677 23 level level NN cord-006870-f5w6fw6q 2677 24 is be VBZ cord-006870-f5w6fw6q 2677 25 not not RB cord-006870-f5w6fw6q 2677 26 reported report VBN cord-006870-f5w6fw6q 2677 27 Mechanically mechanically RB cord-006870-f5w6fw6q 2677 28 ventilated ventilate VBD cord-006870-f5w6fw6q 2677 29 patients patient NNS cord-006870-f5w6fw6q 2677 30 with with IN cord-006870-f5w6fw6q 2677 31 primary primary JJ cord-006870-f5w6fw6q 2677 32 diagnosis diagnosis NN cord-006870-f5w6fw6q 2677 33 of of IN cord-006870-f5w6fw6q 2677 34 Guillain Guillain NNP cord-006870-f5w6fw6q 2677 35 - - HYPH cord-006870-f5w6fw6q 2677 36 Barre Barre NNP cord-006870-f5w6fw6q 2677 37 Syndrome Syndrome NNP cord-006870-f5w6fw6q 2677 38 and and CC cord-006870-f5w6fw6q 2677 39 Myasthenia Myasthenia NNP cord-006870-f5w6fw6q 2677 40 Gravis Gravis NNP cord-006870-f5w6fw6q 2677 41 were be VBD cord-006870-f5w6fw6q 2677 42 identified identify VBN cord-006870-f5w6fw6q 2677 43 from from IN cord-006870-f5w6fw6q 2677 44 the the DT cord-006870-f5w6fw6q 2677 45 Nationwide Nationwide NNP cord-006870-f5w6fw6q 2677 46 In In NNP cord-006870-f5w6fw6q 2677 47 - - HYPH cord-006870-f5w6fw6q 2677 48 Patient patient NN cord-006870-f5w6fw6q 2677 49 Sample sample NN cord-006870-f5w6fw6q 2677 50 ( ( -LRB- cord-006870-f5w6fw6q 2677 51 NIS NIS NNP cord-006870-f5w6fw6q 2677 52 ) ) -RRB- cord-006870-f5w6fw6q 2677 53 database database NN cord-006870-f5w6fw6q 2677 54 for for IN cord-006870-f5w6fw6q 2677 55 the the DT cord-006870-f5w6fw6q 2677 56 years year NNS cord-006870-f5w6fw6q 2677 57 2012 2012 CD cord-006870-f5w6fw6q 2677 58 to to IN cord-006870-f5w6fw6q 2677 59 2014 2014 CD cord-006870-f5w6fw6q 2677 60 Mechanically mechanically RB cord-006870-f5w6fw6q 2677 61 Ventilated ventilate VBN cord-006870-f5w6fw6q 2677 62 MG MG NNP cord-006870-f5w6fw6q 2677 63 patients patient NNS cord-006870-f5w6fw6q 2677 64 ( ( -LRB- cord-006870-f5w6fw6q 2677 65 n=2330 n=2330 CD cord-006870-f5w6fw6q 2677 66 , , , cord-006870-f5w6fw6q 2677 67 mean= mean= JJ cord-006870-f5w6fw6q 2677 68 62+/-19.5 62+/-19.5 CD cord-006870-f5w6fw6q 2677 69 years year NNS cord-006870-f5w6fw6q 2677 70 ) ) -RRB- cord-006870-f5w6fw6q 2677 71 were be VBD cord-006870-f5w6fw6q 2677 72 older old JJR cord-006870-f5w6fw6q 2677 73 compared compare VBN cord-006870-f5w6fw6q 2677 74 to to IN cord-006870-f5w6fw6q 2677 75 GBS GBS NNP cord-006870-f5w6fw6q 2677 76 patients patient NNS cord-006870-f5w6fw6q 2677 77 ( ( -LRB- cord-006870-f5w6fw6q 2677 78 n=2060 n=2060 CD cord-006870-f5w6fw6q 2677 79 , , , cord-006870-f5w6fw6q 2677 80 mean= mean= JJ cord-006870-f5w6fw6q 2677 81 55.9 55.9 CD cord-006870-f5w6fw6q 2677 82 + + CC cord-006870-f5w6fw6q 2678 1 /-20.0 /-20.0 NNP cord-006870-f5w6fw6q 2678 2 years year NNS cord-006870-f5w6fw6q 2678 3 , , , cord-006870-f5w6fw6q 2678 4 p=0.001 p=0.001 NNP cord-006870-f5w6fw6q 2678 5 ) ) -RRB- cord-006870-f5w6fw6q 2678 6 . . . cord-006870-f5w6fw6q 2679 1 Medical medical JJ cord-006870-f5w6fw6q 2679 2 Co Co NNS cord-006870-f5w6fw6q 2679 3 - - NNS cord-006870-f5w6fw6q 2679 4 morbidities morbidity NNS cord-006870-f5w6fw6q 2679 5 were be VBD cord-006870-f5w6fw6q 2679 6 significantly significantly RB cord-006870-f5w6fw6q 2679 7 higher high JJR cord-006870-f5w6fw6q 2679 8 in in IN cord-006870-f5w6fw6q 2679 9 MG MG NNP cord-006870-f5w6fw6q 2679 10 patients patient NNS cord-006870-f5w6fw6q 2679 11 ( ( -LRB- cord-006870-f5w6fw6q 2679 12 diabetes diabetes NN cord-006870-f5w6fw6q 2679 13 mellitus mellitus NN cord-006870-f5w6fw6q 2679 14 , , , cord-006870-f5w6fw6q 2679 15 congestive congestive JJ cord-006870-f5w6fw6q 2679 16 heart heart NN cord-006870-f5w6fw6q 2679 17 failure failure NN cord-006870-f5w6fw6q 2679 18 , , , cord-006870-f5w6fw6q 2679 19 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 2679 20 , , , cord-006870-f5w6fw6q 2679 21 chronic chronic JJ cord-006870-f5w6fw6q 2679 22 lung lung NN cord-006870-f5w6fw6q 2679 23 disease disease NN cord-006870-f5w6fw6q 2679 24 and and CC cord-006870-f5w6fw6q 2679 25 dyslipidemia dyslipidemia NN cord-006870-f5w6fw6q 2679 26 ) ) -RRB- cord-006870-f5w6fw6q 2679 27 whereas whereas IN cord-006870-f5w6fw6q 2679 28 significantly significantly RB cord-006870-f5w6fw6q 2679 29 higher high JJR cord-006870-f5w6fw6q 2679 30 nicotine nicotine NN cord-006870-f5w6fw6q 2679 31 dependence dependence NN cord-006870-f5w6fw6q 2679 32 and and CC cord-006870-f5w6fw6q 2679 33 alcohol alcohol NN cord-006870-f5w6fw6q 2679 34 abuse abuse NN cord-006870-f5w6fw6q 2679 35 were be VBD cord-006870-f5w6fw6q 2679 36 noted note VBN cord-006870-f5w6fw6q 2679 37 in in IN cord-006870-f5w6fw6q 2679 38 GBS GBS NNP cord-006870-f5w6fw6q 2679 39 . . . cord-006870-f5w6fw6q 2680 1 Significantly significantly RB cord-006870-f5w6fw6q 2680 2 higher high JJR cord-006870-f5w6fw6q 2680 3 in in IN cord-006870-f5w6fw6q 2680 4 hospital hospital NN cord-006870-f5w6fw6q 2680 5 complications complication NNS cord-006870-f5w6fw6q 2680 6 of of IN cord-006870-f5w6fw6q 2680 7 pneumonia pneumonia NN cord-006870-f5w6fw6q 2680 8 and and CC cord-006870-f5w6fw6q 2680 9 urinary urinary JJ cord-006870-f5w6fw6q 2680 10 tract tract NN cord-006870-f5w6fw6q 2680 11 infection infection NN cord-006870-f5w6fw6q 2680 12 were be VBD cord-006870-f5w6fw6q 2680 13 noted note VBN cord-006870-f5w6fw6q 2680 14 in in IN cord-006870-f5w6fw6q 2680 15 GBS GBS NNP cord-006870-f5w6fw6q 2680 16 . . . cord-006870-f5w6fw6q 2681 1 Disease disease NN cord-006870-f5w6fw6q 2681 2 severity severity NN cord-006870-f5w6fw6q 2681 3 measured measure VBN cord-006870-f5w6fw6q 2681 4 by by IN cord-006870-f5w6fw6q 2681 5 APDRG APDRG NNP cord-006870-f5w6fw6q 2681 6 severity severity NN cord-006870-f5w6fw6q 2681 7 index index NN cord-006870-f5w6fw6q 2681 8 and and CC cord-006870-f5w6fw6q 2681 9 rate rate NN cord-006870-f5w6fw6q 2681 10 of of IN cord-006870-f5w6fw6q 2681 11 treatment treatment NN cord-006870-f5w6fw6q 2681 12 with with IN cord-006870-f5w6fw6q 2681 13 intravenous intravenous JJ cord-006870-f5w6fw6q 2681 14 immunoglobulin immunoglobulin NN cord-006870-f5w6fw6q 2681 15 and and CC cord-006870-f5w6fw6q 2681 16 plasma plasma NN cord-006870-f5w6fw6q 2681 17 exchange exchange NN cord-006870-f5w6fw6q 2681 18 was be VBD cord-006870-f5w6fw6q 2681 19 comparable comparable JJ cord-006870-f5w6fw6q 2681 20 . . . cord-006870-f5w6fw6q 2682 1 Length length NN cord-006870-f5w6fw6q 2682 2 of of IN cord-006870-f5w6fw6q 2682 3 stay stay NN cord-006870-f5w6fw6q 2682 4 ( ( -LRB- cord-006870-f5w6fw6q 2682 5 25.3 25.3 CD cord-006870-f5w6fw6q 2682 6 ± ± CD cord-006870-f5w6fw6q 2682 7 18.2 18.2 CD cord-006870-f5w6fw6q 2682 8 days day NNS cord-006870-f5w6fw6q 2682 9 , , , cord-006870-f5w6fw6q 2682 10 p p NN cord-006870-f5w6fw6q 2682 11 < < XX cord-006870-f5w6fw6q 2682 12 0.0001 0.0001 CD cord-006870-f5w6fw6q 2682 13 ) ) -RRB- cord-006870-f5w6fw6q 2682 14 ; ; : cord-006870-f5w6fw6q 2682 15 hospital hospital NN cord-006870-f5w6fw6q 2682 16 charges charge NNS cord-006870-f5w6fw6q 2682 17 ( ( -LRB- cord-006870-f5w6fw6q 2682 18 $ $ $ cord-006870-f5w6fw6q 2682 19 353361.2 353361.2 CD cord-006870-f5w6fw6q 2682 20 ± ± CD cord-006870-f5w6fw6q 2682 21 293863.2 293863.2 CD cord-006870-f5w6fw6q 2682 22 vs vs IN cord-006870-f5w6fw6q 2682 23 232160.12 232160.12 CD cord-006870-f5w6fw6q 2682 24 ± ± CD cord-006870-f5w6fw6q 2682 25 222881.3 222881.3 CD cord-006870-f5w6fw6q 2682 26 p p NN cord-006870-f5w6fw6q 2682 27 = = SYM cord-006870-f5w6fw6q 2682 28 0.001 0.001 CD cord-006870-f5w6fw6q 2682 29 ) ) -RRB- cord-006870-f5w6fw6q 2682 30 ; ; : cord-006870-f5w6fw6q 2682 31 moderate moderate JJ cord-006870-f5w6fw6q 2682 32 to to IN cord-006870-f5w6fw6q 2682 33 severe severe JJ cord-006870-f5w6fw6q 2682 34 disability disability NN cord-006870-f5w6fw6q 2682 35 ( ( -LRB- cord-006870-f5w6fw6q 2682 36 86.6 86.6 CD cord-006870-f5w6fw6q 2682 37 % % NN cord-006870-f5w6fw6q 2682 38 vs vs IN cord-006870-f5w6fw6q 2682 39 46.2 46.2 CD cord-006870-f5w6fw6q 2682 40 % % NN cord-006870-f5w6fw6q 2682 41 p p NN cord-006870-f5w6fw6q 2682 42 < < XX cord-006870-f5w6fw6q 2682 43 0.001 0.001 CD cord-006870-f5w6fw6q 2682 44 ) ) -RRB- cord-006870-f5w6fw6q 2682 45 were be VBD cord-006870-f5w6fw6q 2682 46 significantly significantly RB cord-006870-f5w6fw6q 2682 47 higher high JJR cord-006870-f5w6fw6q 2682 48 for for IN cord-006870-f5w6fw6q 2682 49 GBS GBS NNP cord-006870-f5w6fw6q 2682 50 patient patient NN cord-006870-f5w6fw6q 2682 51 compared compare VBN cord-006870-f5w6fw6q 2682 52 to to IN cord-006870-f5w6fw6q 2682 53 MG MG NNP cord-006870-f5w6fw6q 2682 54 . . . cord-006870-f5w6fw6q 2683 1 Inhospital Inhospital NNP cord-006870-f5w6fw6q 2683 2 mortality mortality NN cord-006870-f5w6fw6q 2683 3 was be VBD cord-006870-f5w6fw6q 2683 4 comparable comparable JJ cord-006870-f5w6fw6q 2683 5 ( ( -LRB- cord-006870-f5w6fw6q 2683 6 8.7 8.7 CD cord-006870-f5w6fw6q 2683 7 % % NN cord-006870-f5w6fw6q 2683 8 GBS GBS NNP cord-006870-f5w6fw6q 2683 9 vs vs IN cord-006870-f5w6fw6q 2683 10 8.6 8.6 CD cord-006870-f5w6fw6q 2683 11 % % NN cord-006870-f5w6fw6q 2683 12 MG MG NNP cord-006870-f5w6fw6q 2683 13 , , , cord-006870-f5w6fw6q 2683 14 p p NN cord-006870-f5w6fw6q 2683 15 = = SYM cord-006870-f5w6fw6q 2683 16 0.93 0.93 CD cord-006870-f5w6fw6q 2683 17 ) ) -RRB- cord-006870-f5w6fw6q 2683 18 . . . cord-006870-f5w6fw6q 2684 1 In in IN cord-006870-f5w6fw6q 2684 2 multivariate multivariate JJ cord-006870-f5w6fw6q 2684 3 analysis analysis NN cord-006870-f5w6fw6q 2684 4 after after IN cord-006870-f5w6fw6q 2684 5 adjusting adjust VBG cord-006870-f5w6fw6q 2684 6 for for IN cord-006870-f5w6fw6q 2684 7 confounders confounder NNS cord-006870-f5w6fw6q 2684 8 including include VBG cord-006870-f5w6fw6q 2684 9 treatment treatment NN cord-006870-f5w6fw6q 2684 10 , , , cord-006870-f5w6fw6q 2684 11 myasthenia myasthenia NN cord-006870-f5w6fw6q 2684 12 gravis gravis NN cord-006870-f5w6fw6q 2684 13 patients patient NNS cord-006870-f5w6fw6q 2684 14 had have VBD cord-006870-f5w6fw6q 2684 15 significantly significantly RB cord-006870-f5w6fw6q 2684 16 less less JJR cord-006870-f5w6fw6q 2684 17 disability disability NN cord-006870-f5w6fw6q 2684 18 ( ( -LRB- cord-006870-f5w6fw6q 2684 19 OR or CC cord-006870-f5w6fw6q 2684 20 0.06 0.06 CD cord-006870-f5w6fw6q 2684 21 ( ( -LRB- cord-006870-f5w6fw6q 2684 22 95 95 CD cord-006870-f5w6fw6q 2684 23 % % NN cord-006870-f5w6fw6q 2684 24 CI CI NNP cord-006870-f5w6fw6q 2684 25 0.03 0.03 CD cord-006870-f5w6fw6q 2684 26 - - HYPH cord-006870-f5w6fw6q 2684 27 0.10 0.10 CD cord-006870-f5w6fw6q 2684 28 ) ) -RRB- cord-006870-f5w6fw6q 2684 29 and and CC cord-006870-f5w6fw6q 2684 30 shorter short JJR cord-006870-f5w6fw6q 2684 31 length length NN cord-006870-f5w6fw6q 2684 32 of of IN cord-006870-f5w6fw6q 2684 33 stay stay NN cord-006870-f5w6fw6q 2684 34 ( ( -LRB- cord-006870-f5w6fw6q 2684 35 OR or CC cord-006870-f5w6fw6q 2684 36 0.32 0.32 CD cord-006870-f5w6fw6q 2684 37 , , , cord-006870-f5w6fw6q 2684 38 95 95 CD cord-006870-f5w6fw6q 2684 39 % % NN cord-006870-f5w6fw6q 2684 40 CI CI NNP cord-006870-f5w6fw6q 2684 41 0.16 0.16 CD cord-006870-f5w6fw6q 2684 42 - - HYPH cord-006870-f5w6fw6q 2684 43 0.61 0.61 CD cord-006870-f5w6fw6q 2684 44 ) ) -RRB- cord-006870-f5w6fw6q 2684 45 . . . cord-006870-f5w6fw6q 2685 1 Mechanically mechanically RB cord-006870-f5w6fw6q 2685 2 ventilated ventilate VBN cord-006870-f5w6fw6q 2685 3 GBS GBS NNP cord-006870-f5w6fw6q 2685 4 patients patient NNS cord-006870-f5w6fw6q 2685 5 have have VBP cord-006870-f5w6fw6q 2685 6 higher high JJR cord-006870-f5w6fw6q 2685 7 in in IN cord-006870-f5w6fw6q 2685 8 - - HYPH cord-006870-f5w6fw6q 2685 9 hospital hospital NN cord-006870-f5w6fw6q 2685 10 complications complication NNS cord-006870-f5w6fw6q 2685 11 , , , cord-006870-f5w6fw6q 2685 12 length length NN cord-006870-f5w6fw6q 2685 13 - - HYPH cord-006870-f5w6fw6q 2685 14 of of IN cord-006870-f5w6fw6q 2685 15 - - HYPH cord-006870-f5w6fw6q 2685 16 stay stay NN cord-006870-f5w6fw6q 2685 17 , , , cord-006870-f5w6fw6q 2685 18 and and CC cord-006870-f5w6fw6q 2685 19 disability disability NN cord-006870-f5w6fw6q 2685 20 compared compare VBN cord-006870-f5w6fw6q 2685 21 to to IN cord-006870-f5w6fw6q 2685 22 MG MG NNP cord-006870-f5w6fw6q 2685 23 . . . cord-006870-f5w6fw6q 2686 1 This this DT cord-006870-f5w6fw6q 2686 2 may may MD cord-006870-f5w6fw6q 2686 3 reflect reflect VB cord-006870-f5w6fw6q 2686 4 a a DT cord-006870-f5w6fw6q 2686 5 delay delay NN cord-006870-f5w6fw6q 2686 6 in in IN cord-006870-f5w6fw6q 2686 7 diagnosis diagnosis NN cord-006870-f5w6fw6q 2686 8 of of IN cord-006870-f5w6fw6q 2686 9 GBS GBS NNP cord-006870-f5w6fw6q 2686 10 at at IN cord-006870-f5w6fw6q 2686 11 admission admission NN cord-006870-f5w6fw6q 2686 12 and and CC cord-006870-f5w6fw6q 2686 13 poor poor JJ cord-006870-f5w6fw6q 2686 14 response response NN cord-006870-f5w6fw6q 2686 15 to to IN cord-006870-f5w6fw6q 2686 16 immunotherapy immunotherapy NN cord-006870-f5w6fw6q 2686 17 in in IN cord-006870-f5w6fw6q 2686 18 certain certain JJ cord-006870-f5w6fw6q 2686 19 GBS GBS NNP cord-006870-f5w6fw6q 2686 20 variants variant NNS cord-006870-f5w6fw6q 2686 21 . . . cord-006870-f5w6fw6q 2687 1 Betrixaban Betrixaban NNP cord-006870-f5w6fw6q 2687 2 is be VBZ cord-006870-f5w6fw6q 2687 3 an an DT cord-006870-f5w6fw6q 2687 4 inhibitor inhibitor NN cord-006870-f5w6fw6q 2687 5 of of IN cord-006870-f5w6fw6q 2687 6 factor factor NN cord-006870-f5w6fw6q 2687 7 Xa Xa NNP cord-006870-f5w6fw6q 2687 8 ( ( -LRB- cord-006870-f5w6fw6q 2687 9 FXa FXa NNP cord-006870-f5w6fw6q 2687 10 ) ) -RRB- cord-006870-f5w6fw6q 2687 11 for for IN cord-006870-f5w6fw6q 2687 12 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2687 13 of of IN cord-006870-f5w6fw6q 2687 14 venous venous JJ cord-006870-f5w6fw6q 2687 15 thromboembolism thromboembolism NN cord-006870-f5w6fw6q 2687 16 ( ( -LRB- cord-006870-f5w6fw6q 2687 17 VTE VTE NNP cord-006870-f5w6fw6q 2687 18 ) ) -RRB- cord-006870-f5w6fw6q 2687 19 in in IN cord-006870-f5w6fw6q 2687 20 at at IN cord-006870-f5w6fw6q 2687 21 - - HYPH cord-006870-f5w6fw6q 2687 22 risk risk NN cord-006870-f5w6fw6q 2687 23 patients patient NNS cord-006870-f5w6fw6q 2687 24 hospitalized hospitalize VBN cord-006870-f5w6fw6q 2687 25 for for IN cord-006870-f5w6fw6q 2687 26 acute acute JJ cord-006870-f5w6fw6q 2687 27 medical medical JJ cord-006870-f5w6fw6q 2687 28 illness illness NN cord-006870-f5w6fw6q 2687 29 . . . cord-006870-f5w6fw6q 2688 1 A a DT cord-006870-f5w6fw6q 2688 2 phase phase NN cord-006870-f5w6fw6q 2688 3 3 3 CD cord-006870-f5w6fw6q 2688 4 trial trial NN cord-006870-f5w6fw6q 2688 5 ( ( -LRB- cord-006870-f5w6fw6q 2688 6 APEX APEX NNP cord-006870-f5w6fw6q 2688 7 ) ) -RRB- cord-006870-f5w6fw6q 2688 8 compared compare VBN cord-006870-f5w6fw6q 2688 9 extended extend VBN cord-006870-f5w6fw6q 2688 10 - - HYPH cord-006870-f5w6fw6q 2688 11 duration duration NN cord-006870-f5w6fw6q 2688 12 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2688 13 with with IN cord-006870-f5w6fw6q 2688 14 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2688 15 to to TO cord-006870-f5w6fw6q 2688 16 enoxaparin enoxaparin VB cord-006870-f5w6fw6q 2688 17 in in IN cord-006870-f5w6fw6q 2688 18 acute acute JJ cord-006870-f5w6fw6q 2688 19 medically medically RB cord-006870-f5w6fw6q 2688 20 ill ill JJ cord-006870-f5w6fw6q 2688 21 patients patient NNS cord-006870-f5w6fw6q 2688 22 ; ; : cord-006870-f5w6fw6q 2688 23 the the DT cord-006870-f5w6fw6q 2688 24 effect effect NN cord-006870-f5w6fw6q 2688 25 of of IN cord-006870-f5w6fw6q 2688 26 patient patient JJ cord-006870-f5w6fw6q 2688 27 characteristics characteristic NNS cord-006870-f5w6fw6q 2688 28 on on IN cord-006870-f5w6fw6q 2688 29 population population NN cord-006870-f5w6fw6q 2688 30 pharmacokinetics pharmacokinetic NNS cord-006870-f5w6fw6q 2688 31 and and CC cord-006870-f5w6fw6q 2688 32 exposure exposure NN cord-006870-f5w6fw6q 2688 33 - - HYPH cord-006870-f5w6fw6q 2688 34 response response NN cord-006870-f5w6fw6q 2688 35 relationships relationship NNS cord-006870-f5w6fw6q 2688 36 is be VBZ cord-006870-f5w6fw6q 2688 37 analyzed analyze VBN cord-006870-f5w6fw6q 2688 38 here here RB cord-006870-f5w6fw6q 2688 39 . . . cord-006870-f5w6fw6q 2689 1 Patients patient NNS cord-006870-f5w6fw6q 2689 2 received receive VBD cord-006870-f5w6fw6q 2689 3 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2689 4 ( ( -LRB- cord-006870-f5w6fw6q 2689 5 35 35 CD cord-006870-f5w6fw6q 2689 6 - - SYM cord-006870-f5w6fw6q 2689 7 42 42 CD cord-006870-f5w6fw6q 2689 8 days day NNS cord-006870-f5w6fw6q 2689 9 ; ; : cord-006870-f5w6fw6q 2689 10 n=3,759 n=3,759 NNP cord-006870-f5w6fw6q 2689 11 ) ) -RRB- cord-006870-f5w6fw6q 2689 12 or or CC cord-006870-f5w6fw6q 2689 13 enoxaparin enoxaparin NNP cord-006870-f5w6fw6q 2689 14 ( ( -LRB- cord-006870-f5w6fw6q 2689 15 10±4 10±4 CD cord-006870-f5w6fw6q 2689 16 days day NNS cord-006870-f5w6fw6q 2689 17 ; ; : cord-006870-f5w6fw6q 2689 18 n=3,754 n=3,754 NNP cord-006870-f5w6fw6q 2689 19 ) ) -RRB- cord-006870-f5w6fw6q 2689 20 . . . cord-006870-f5w6fw6q 2690 1 The the DT cord-006870-f5w6fw6q 2690 2 primary primary JJ cord-006870-f5w6fw6q 2690 3 efficacy efficacy NN cord-006870-f5w6fw6q 2690 4 and and CC cord-006870-f5w6fw6q 2690 5 safety safety NN cord-006870-f5w6fw6q 2690 6 endpoints endpoint NNS cord-006870-f5w6fw6q 2690 7 were be VBD cord-006870-f5w6fw6q 2690 8 composite composite JJ cord-006870-f5w6fw6q 2690 9 occurrence occurrence NN cord-006870-f5w6fw6q 2690 10 of of IN cord-006870-f5w6fw6q 2690 11 VTE VTE NNP cord-006870-f5w6fw6q 2690 12 events event NNS cord-006870-f5w6fw6q 2690 13 and and CC cord-006870-f5w6fw6q 2690 14 incidence incidence NN cord-006870-f5w6fw6q 2690 15 of of IN cord-006870-f5w6fw6q 2690 16 major major JJ cord-006870-f5w6fw6q 2690 17 bleeding bleeding NN cord-006870-f5w6fw6q 2690 18 , , , cord-006870-f5w6fw6q 2690 19 respectively respectively RB cord-006870-f5w6fw6q 2690 20 . . . cord-006870-f5w6fw6q 2691 1 Betrixaban Betrixaban NNP cord-006870-f5w6fw6q 2691 2 dose dose NN cord-006870-f5w6fw6q 2691 3 was be VBD cord-006870-f5w6fw6q 2691 4 80 80 CD cord-006870-f5w6fw6q 2691 5 mg mg NN cord-006870-f5w6fw6q 2692 1 PO PO NNP cord-006870-f5w6fw6q 2692 2 QD QD NNP cord-006870-f5w6fw6q 2692 3 ( ( -LRB- cord-006870-f5w6fw6q 2692 4 40 40 CD cord-006870-f5w6fw6q 2692 5 mg mg NN cord-006870-f5w6fw6q 2692 6 PO PO NNP cord-006870-f5w6fw6q 2692 7 QD QD NNP cord-006870-f5w6fw6q 2692 8 for for IN cord-006870-f5w6fw6q 2692 9 patients patient NNS cord-006870-f5w6fw6q 2692 10 with with IN cord-006870-f5w6fw6q 2692 11 severe severe JJ cord-006870-f5w6fw6q 2692 12 renal renal JJ cord-006870-f5w6fw6q 2692 13 insufficiency/ insufficiency/ CD cord-006870-f5w6fw6q 2693 1 requiring require VBG cord-006870-f5w6fw6q 2693 2 concomitant concomitant JJ cord-006870-f5w6fw6q 2693 3 P p NN cord-006870-f5w6fw6q 2693 4 - - HYPH cord-006870-f5w6fw6q 2693 5 glycoprotein glycoprotein NN cord-006870-f5w6fw6q 2693 6 inhibitor inhibitor NN cord-006870-f5w6fw6q 2693 7 ) ) -RRB- cord-006870-f5w6fw6q 2693 8 . . . cord-006870-f5w6fw6q 2694 1 Pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2694 2 samples sample NNS cord-006870-f5w6fw6q 2694 3 were be VBD cord-006870-f5w6fw6q 2694 4 collected collect VBN cord-006870-f5w6fw6q 2694 5 -5 -5 NNP cord-006870-f5w6fw6q 2694 6 hours hour NNS cord-006870-f5w6fw6q 2694 7 or or CC cord-006870-f5w6fw6q 2694 8 10 10 CD cord-006870-f5w6fw6q 2694 9 - - SYM cord-006870-f5w6fw6q 2694 10 30 30 CD cord-006870-f5w6fw6q 2694 11 hours hour NNS cord-006870-f5w6fw6q 2694 12 after after IN cord-006870-f5w6fw6q 2694 13 the the DT cord-006870-f5w6fw6q 2694 14 most most RBS cord-006870-f5w6fw6q 2694 15 recent recent JJ cord-006870-f5w6fw6q 2694 16 dose dose NN cord-006870-f5w6fw6q 2694 17 of of IN cord-006870-f5w6fw6q 2694 18 study study NN cord-006870-f5w6fw6q 2694 19 medication medication NN cord-006870-f5w6fw6q 2694 20 . . . cord-006870-f5w6fw6q 2695 1 Patient patient JJ cord-006870-f5w6fw6q 2695 2 characteristics characteristic NNS cord-006870-f5w6fw6q 2695 3 included include VBD cord-006870-f5w6fw6q 2695 4 age age NN cord-006870-f5w6fw6q 2695 5 , , , cord-006870-f5w6fw6q 2695 6 sex sex NN cord-006870-f5w6fw6q 2695 7 , , , cord-006870-f5w6fw6q 2695 8 race race NN cord-006870-f5w6fw6q 2695 9 , , , cord-006870-f5w6fw6q 2695 10 region region NN cord-006870-f5w6fw6q 2695 11 , , , cord-006870-f5w6fw6q 2695 12 body body NN cord-006870-f5w6fw6q 2695 13 weight weight NN cord-006870-f5w6fw6q 2695 14 , , , cord-006870-f5w6fw6q 2695 15 CrCl CrCl NNP cord-006870-f5w6fw6q 2695 16 category category NN cord-006870-f5w6fw6q 2695 17 , , , cord-006870-f5w6fw6q 2695 18 and and CC cord-006870-f5w6fw6q 2695 19 specific specific JJ cord-006870-f5w6fw6q 2695 20 P p NN cord-006870-f5w6fw6q 2695 21 - - HYPH cord-006870-f5w6fw6q 2695 22 glycoprotein glycoprotein NN cord-006870-f5w6fw6q 2695 23 inhibitor inhibitor NN cord-006870-f5w6fw6q 2695 24 . . . cord-006870-f5w6fw6q 2696 1 3,146 3,146 CD cord-006870-f5w6fw6q 2696 2 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2696 3 samples sample NNS cord-006870-f5w6fw6q 2696 4 were be VBD cord-006870-f5w6fw6q 2696 5 analyzed analyze VBN cord-006870-f5w6fw6q 2696 6 . . . cord-006870-f5w6fw6q 2697 1 At at IN cord-006870-f5w6fw6q 2697 2 80 80 CD cord-006870-f5w6fw6q 2697 3 mg mg NNS cord-006870-f5w6fw6q 2697 4 , , , cord-006870-f5w6fw6q 2697 5 the the DT cord-006870-f5w6fw6q 2697 6 projected project VBN cord-006870-f5w6fw6q 2697 7 concentration concentration NN cord-006870-f5w6fw6q 2697 8 was be VBD cord-006870-f5w6fw6q 2697 9 18.8ng 18.8ng CD cord-006870-f5w6fw6q 2697 10 / / SYM cord-006870-f5w6fw6q 2697 11 mL ml NN cord-006870-f5w6fw6q 2697 12 at at IN cord-006870-f5w6fw6q 2697 13 2 2 CD cord-006870-f5w6fw6q 2697 14 hours hour NNS cord-006870-f5w6fw6q 2697 15 post post NN cord-006870-f5w6fw6q 2697 16 - - JJ cord-006870-f5w6fw6q 2697 17 dose dose JJ cord-006870-f5w6fw6q 2697 18 and and CC cord-006870-f5w6fw6q 2697 19 16.1ng 16.1ng NNP cord-006870-f5w6fw6q 2697 20 / / SYM cord-006870-f5w6fw6q 2697 21 mL ml NN cord-006870-f5w6fw6q 2697 22 at at IN cord-006870-f5w6fw6q 2697 23 20 20 CD cord-006870-f5w6fw6q 2697 24 hours hour NNS cord-006870-f5w6fw6q 2697 25 post post NN cord-006870-f5w6fw6q 2697 26 - - JJ cord-006870-f5w6fw6q 2697 27 dose dose JJ cord-006870-f5w6fw6q 2697 28 , , , cord-006870-f5w6fw6q 2697 29 showing show VBG cord-006870-f5w6fw6q 2697 30 a a DT cord-006870-f5w6fw6q 2697 31 stable stable JJ cord-006870-f5w6fw6q 2697 32 daily daily JJ cord-006870-f5w6fw6q 2697 33 concentration concentration NN cord-006870-f5w6fw6q 2697 34 . . . cord-006870-f5w6fw6q 2698 1 Coadministration Coadministration NNP cord-006870-f5w6fw6q 2698 2 of of IN cord-006870-f5w6fw6q 2698 3 2 2 CD cord-006870-f5w6fw6q 2698 4 P p NN cord-006870-f5w6fw6q 2698 5 - - HYPH cord-006870-f5w6fw6q 2698 6 glycoprotein glycoprotein VBG cord-006870-f5w6fw6q 2698 7 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2698 8 on on IN cord-006870-f5w6fw6q 2698 9 the the DT cord-006870-f5w6fw6q 2698 10 day day NN cord-006870-f5w6fw6q 2698 11 of of IN cord-006870-f5w6fw6q 2698 12 sampling sampling NN cord-006870-f5w6fw6q 2698 13 more more JJR cord-006870-f5w6fw6q 2698 14 than than IN cord-006870-f5w6fw6q 2698 15 doubled double VBN cord-006870-f5w6fw6q 2698 16 betrixaban betrixaban JJ cord-006870-f5w6fw6q 2698 17 concentration concentration NN cord-006870-f5w6fw6q 2698 18 to to IN cord-006870-f5w6fw6q 2698 19 ~35ng ~35ng CD cord-006870-f5w6fw6q 2698 20 / / SYM cord-006870-f5w6fw6q 2698 21 mL ml NN cord-006870-f5w6fw6q 2698 22 at at IN cord-006870-f5w6fw6q 2698 23 20 20 CD cord-006870-f5w6fw6q 2698 24 hours hour NNS cord-006870-f5w6fw6q 2698 25 post post NN cord-006870-f5w6fw6q 2698 26 - - JJ cord-006870-f5w6fw6q 2698 27 dose dose NN cord-006870-f5w6fw6q 2698 28 . . . cord-006870-f5w6fw6q 2699 1 At at IN cord-006870-f5w6fw6q 2699 2 40 40 CD cord-006870-f5w6fw6q 2699 3 mg mg NNS cord-006870-f5w6fw6q 2699 4 , , , cord-006870-f5w6fw6q 2699 5 the the DT cord-006870-f5w6fw6q 2699 6 projected project VBN cord-006870-f5w6fw6q 2699 7 concentration concentration NN cord-006870-f5w6fw6q 2699 8 was be VBD cord-006870-f5w6fw6q 2699 9 7.2ng 7.2ng CD cord-006870-f5w6fw6q 2699 10 / / SYM cord-006870-f5w6fw6q 2699 11 mL ml NN cord-006870-f5w6fw6q 2699 12 at at IN cord-006870-f5w6fw6q 2699 13 20 20 CD cord-006870-f5w6fw6q 2699 14 hours hour NNS cord-006870-f5w6fw6q 2699 15 post post NN cord-006870-f5w6fw6q 2699 16 - - JJ cord-006870-f5w6fw6q 2699 17 dose dose JJ cord-006870-f5w6fw6q 2699 18 , , , cord-006870-f5w6fw6q 2699 19 indicating indicate VBG cord-006870-f5w6fw6q 2699 20 a a DT cord-006870-f5w6fw6q 2699 21 greater great JJR cord-006870-f5w6fw6q 2699 22 - - HYPH cord-006870-f5w6fw6q 2699 23 than than IN cord-006870-f5w6fw6q 2699 24 - - HYPH cord-006870-f5w6fw6q 2699 25 dose dose NN cord-006870-f5w6fw6q 2699 26 - - HYPH cord-006870-f5w6fw6q 2699 27 proportional proportional JJ cord-006870-f5w6fw6q 2699 28 exposure exposure NN cord-006870-f5w6fw6q 2699 29 relationship relationship NN cord-006870-f5w6fw6q 2699 30 . . . cord-006870-f5w6fw6q 2700 1 Patient patient JJ cord-006870-f5w6fw6q 2700 2 age age NN cord-006870-f5w6fw6q 2700 3 , , , cord-006870-f5w6fw6q 2700 4 sex sex NN cord-006870-f5w6fw6q 2700 5 , , , cord-006870-f5w6fw6q 2700 6 weight weight NN cord-006870-f5w6fw6q 2700 7 , , , cord-006870-f5w6fw6q 2700 8 CrCl CrCl NNP cord-006870-f5w6fw6q 2700 9 category category NN cord-006870-f5w6fw6q 2700 10 , , , cord-006870-f5w6fw6q 2700 11 P p NN cord-006870-f5w6fw6q 2700 12 - - HYPH cord-006870-f5w6fw6q 2700 13 glycoprotein glycoprotein NN cord-006870-f5w6fw6q 2700 14 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2700 15 , , , cord-006870-f5w6fw6q 2700 16 and and CC cord-006870-f5w6fw6q 2700 17 region region NN cord-006870-f5w6fw6q 2700 18 were be VBD cord-006870-f5w6fw6q 2700 19 significant significant JJ cord-006870-f5w6fw6q 2700 20 covariates covariate NNS cord-006870-f5w6fw6q 2700 21 affecting affect VBG cord-006870-f5w6fw6q 2700 22 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2700 23 pharmacokinetics pharmacokinetic NNS cord-006870-f5w6fw6q 2700 24 . . . cord-006870-f5w6fw6q 2701 1 The the DT cord-006870-f5w6fw6q 2701 2 exposure exposure NN cord-006870-f5w6fw6q 2701 3 - - HYPH cord-006870-f5w6fw6q 2701 4 response response NN cord-006870-f5w6fw6q 2701 5 relationship relationship NN cord-006870-f5w6fw6q 2701 6 for for IN cord-006870-f5w6fw6q 2701 7 the the DT cord-006870-f5w6fw6q 2701 8 primary primary JJ cord-006870-f5w6fw6q 2701 9 efficacy efficacy NN cord-006870-f5w6fw6q 2701 10 endpoint endpoint NN cord-006870-f5w6fw6q 2701 11 was be VBD cord-006870-f5w6fw6q 2701 12 not not RB cord-006870-f5w6fw6q 2701 13 significant significant JJ cord-006870-f5w6fw6q 2701 14 , , , cord-006870-f5w6fw6q 2701 15 but but CC cord-006870-f5w6fw6q 2701 16 the the DT cord-006870-f5w6fw6q 2701 17 relationship relationship NN cord-006870-f5w6fw6q 2701 18 between between IN cord-006870-f5w6fw6q 2701 19 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2701 20 concentration concentration NN cord-006870-f5w6fw6q 2701 21 and and CC cord-006870-f5w6fw6q 2701 22 major major JJ cord-006870-f5w6fw6q 2701 23 / / , cord-006870-f5w6fw6q 2701 24 clinically clinically RB cord-006870-f5w6fw6q 2701 25 relevant relevant JJ cord-006870-f5w6fw6q 2701 26 nonmajor nonmajor NN cord-006870-f5w6fw6q 2701 27 bleeding bleed VBG cord-006870-f5w6fw6q 2701 28 was be VBD cord-006870-f5w6fw6q 2701 29 significant significant JJ cord-006870-f5w6fw6q 2701 30 in in IN cord-006870-f5w6fw6q 2701 31 multivariate multivariate JJ cord-006870-f5w6fw6q 2701 32 testing testing NN cord-006870-f5w6fw6q 2701 33 ( ( -LRB- cord-006870-f5w6fw6q 2701 34 P=0.011 P=0.011 NNP cord-006870-f5w6fw6q 2701 35 ) ) -RRB- cord-006870-f5w6fw6q 2701 36 . . . cord-006870-f5w6fw6q 2702 1 The the DT cord-006870-f5w6fw6q 2702 2 betrixaban betrixaban CD cord-006870-f5w6fw6q 2702 3 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2702 4 profile profile NN cord-006870-f5w6fw6q 2702 5 exhibited exhibit VBD cord-006870-f5w6fw6q 2702 6 stable stable JJ cord-006870-f5w6fw6q 2702 7 serum serum NN cord-006870-f5w6fw6q 2702 8 concentrations concentration NNS cord-006870-f5w6fw6q 2702 9 with with IN cord-006870-f5w6fw6q 2702 10 QD qd NN cord-006870-f5w6fw6q 2702 11 dosing dose VBG cord-006870-f5w6fw6q 2702 12 . . . cord-006870-f5w6fw6q 2703 1 Several several JJ cord-006870-f5w6fw6q 2703 2 covariates covariate NNS cord-006870-f5w6fw6q 2703 3 had have VBD cord-006870-f5w6fw6q 2703 4 a a DT cord-006870-f5w6fw6q 2703 5 15%-20 15%-20 CD cord-006870-f5w6fw6q 2703 6 % % NN cord-006870-f5w6fw6q 2703 7 effect effect NN cord-006870-f5w6fw6q 2703 8 on on IN cord-006870-f5w6fw6q 2703 9 betrixaban betrixaban NNP cord-006870-f5w6fw6q 2703 10 concentration concentration NN cord-006870-f5w6fw6q 2703 11 , , , cord-006870-f5w6fw6q 2703 12 but but CC cord-006870-f5w6fw6q 2703 13 no no DT cord-006870-f5w6fw6q 2703 14 effect effect NN cord-006870-f5w6fw6q 2703 15 on on IN cord-006870-f5w6fw6q 2703 16 efficacy efficacy NN cord-006870-f5w6fw6q 2703 17 / / SYM cord-006870-f5w6fw6q 2703 18 safety safety NN cord-006870-f5w6fw6q 2703 19 . . . cord-006870-f5w6fw6q 2704 1 Betrixaban Betrixaban NNP cord-006870-f5w6fw6q 2704 2 dose dose NN cord-006870-f5w6fw6q 2704 3 should should MD cord-006870-f5w6fw6q 2704 4 be be VB cord-006870-f5w6fw6q 2704 5 adjusted adjust VBN cord-006870-f5w6fw6q 2704 6 to to IN cord-006870-f5w6fw6q 2704 7 40 40 CD cord-006870-f5w6fw6q 2704 8 mg mg NN cord-006870-f5w6fw6q 2704 9 for for IN cord-006870-f5w6fw6q 2704 10 patients patient NNS cord-006870-f5w6fw6q 2704 11 taking take VBG cord-006870-f5w6fw6q 2704 12 amiodarone amiodarone NN cord-006870-f5w6fw6q 2704 13 or or CC cord-006870-f5w6fw6q 2704 14 clarithromycin clarithromycin NNS cord-006870-f5w6fw6q 2704 15 , , , cord-006870-f5w6fw6q 2704 16 but but CC cord-006870-f5w6fw6q 2704 17 not not RB cord-006870-f5w6fw6q 2704 18 other other JJ cord-006870-f5w6fw6q 2704 19 P p NN cord-006870-f5w6fw6q 2704 20 - - HYPH cord-006870-f5w6fw6q 2704 21 glycoprotein glycoprotein NN cord-006870-f5w6fw6q 2704 22 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2704 23 . . . cord-006870-f5w6fw6q 2705 1 Andexanet Andexanet NNP cord-006870-f5w6fw6q 2705 2 alfa alfa NNP cord-006870-f5w6fw6q 2705 3 is be VBZ cord-006870-f5w6fw6q 2705 4 being be VBG cord-006870-f5w6fw6q 2705 5 investigated investigate VBN cord-006870-f5w6fw6q 2705 6 for for IN cord-006870-f5w6fw6q 2705 7 reversal reversal NN cord-006870-f5w6fw6q 2705 8 of of IN cord-006870-f5w6fw6q 2705 9 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2705 10 by by IN cord-006870-f5w6fw6q 2705 11 factor factor NN cord-006870-f5w6fw6q 2705 12 Xa Xa NNP cord-006870-f5w6fw6q 2705 13 ( ( -LRB- cord-006870-f5w6fw6q 2705 14 FXa FXa NNPS cord-006870-f5w6fw6q 2705 15 ) ) -RRB- cord-006870-f5w6fw6q 2705 16 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2705 17 . . . cord-006870-f5w6fw6q 2706 1 A a DT cord-006870-f5w6fw6q 2706 2 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2706 3 / / SYM cord-006870-f5w6fw6q 2706 4 pharmacodynamics pharmacodynamic NNS cord-006870-f5w6fw6q 2706 5 model model NN cord-006870-f5w6fw6q 2706 6 , , , cord-006870-f5w6fw6q 2706 7 developed develop VBN cord-006870-f5w6fw6q 2706 8 in in IN cord-006870-f5w6fw6q 2706 9 healthy healthy JJ cord-006870-f5w6fw6q 2706 10 subjects subject NNS cord-006870-f5w6fw6q 2706 11 , , , cord-006870-f5w6fw6q 2706 12 predicted predict VBD cord-006870-f5w6fw6q 2706 13 the the DT cord-006870-f5w6fw6q 2706 14 andexanet andexanet NNP cord-006870-f5w6fw6q 2706 15 regimen regimen NN cord-006870-f5w6fw6q 2706 16 required require VBN cord-006870-f5w6fw6q 2706 17 to to TO cord-006870-f5w6fw6q 2706 18 reverse reverse VB cord-006870-f5w6fw6q 2706 19 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 2706 20 by by IN cord-006870-f5w6fw6q 2706 21 FXa FXa NNS cord-006870-f5w6fw6q 2706 22 inhibitors inhibitor NNS cord-006870-f5w6fw6q 2706 23 . . . cord-006870-f5w6fw6q 2707 1 The the DT cord-006870-f5w6fw6q 2707 2 current current JJ cord-006870-f5w6fw6q 2707 3 analysis analysis NN cord-006870-f5w6fw6q 2707 4 validated validate VBD cord-006870-f5w6fw6q 2707 5 the the DT cord-006870-f5w6fw6q 2707 6 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2707 7 / / SYM cord-006870-f5w6fw6q 2707 8 pharmacodynamic pharmacodynamic JJ cord-006870-f5w6fw6q 2707 9 model model NN cord-006870-f5w6fw6q 2707 10 using use VBG cord-006870-f5w6fw6q 2707 11 interim interim JJ cord-006870-f5w6fw6q 2707 12 data datum NNS cord-006870-f5w6fw6q 2707 13 from from IN cord-006870-f5w6fw6q 2707 14 the the DT cord-006870-f5w6fw6q 2707 15 ANNEXA-4 ANNEXA-4 NNP cord-006870-f5w6fw6q 2707 16 study study NN cord-006870-f5w6fw6q 2707 17 in in IN cord-006870-f5w6fw6q 2707 18 patients patient NNS cord-006870-f5w6fw6q 2707 19 with with IN cord-006870-f5w6fw6q 2707 20 acute acute JJ cord-006870-f5w6fw6q 2707 21 major major JJ cord-006870-f5w6fw6q 2707 22 bleeding bleeding NN cord-006870-f5w6fw6q 2707 23 . . . cord-006870-f5w6fw6q 2708 1 In in IN cord-006870-f5w6fw6q 2708 2 ANNEXA-4 ANNEXA-4 NNP cord-006870-f5w6fw6q 2708 3 , , , cord-006870-f5w6fw6q 2708 4 an an DT cord-006870-f5w6fw6q 2708 5 ongoing ongoing JJ cord-006870-f5w6fw6q 2708 6 prospective prospective JJ cord-006870-f5w6fw6q 2708 7 , , , cord-006870-f5w6fw6q 2708 8 open open JJ cord-006870-f5w6fw6q 2708 9 - - HYPH cord-006870-f5w6fw6q 2708 10 label label NN cord-006870-f5w6fw6q 2708 11 study study NN cord-006870-f5w6fw6q 2708 12 , , , cord-006870-f5w6fw6q 2708 13 bleeding bleed VBG cord-006870-f5w6fw6q 2708 14 anticoagulated anticoagulate VBN cord-006870-f5w6fw6q 2708 15 patients patient NNS cord-006870-f5w6fw6q 2708 16 received receive VBD cord-006870-f5w6fw6q 2708 17 IV IV NNP cord-006870-f5w6fw6q 2708 18 andexanet andexanet NNP cord-006870-f5w6fw6q 2708 19 bolus bolus NN cord-006870-f5w6fw6q 2708 20 ( ( -LRB- cord-006870-f5w6fw6q 2708 21 400 400 CD cord-006870-f5w6fw6q 2708 22 or or CC cord-006870-f5w6fw6q 2708 23 800 800 CD cord-006870-f5w6fw6q 2708 24 mg mg NNS cord-006870-f5w6fw6q 2708 25 ) ) -RRB- cord-006870-f5w6fw6q 2708 26 followed follow VBN cord-006870-f5w6fw6q 2708 27 by by IN cord-006870-f5w6fw6q 2708 28 120-minute 120-minute CD cord-006870-f5w6fw6q 2708 29 infusion infusion NN cord-006870-f5w6fw6q 2708 30 ( ( -LRB- cord-006870-f5w6fw6q 2708 31 4 4 CD cord-006870-f5w6fw6q 2708 32 or or CC cord-006870-f5w6fw6q 2708 33 8 8 CD cord-006870-f5w6fw6q 2708 34 mg mg NNP cord-006870-f5w6fw6q 2708 35 / / SYM cord-006870-f5w6fw6q 2708 36 min min NNP cord-006870-f5w6fw6q 2708 37 ) ) -RRB- cord-006870-f5w6fw6q 2708 38 . . . cord-006870-f5w6fw6q 2709 1 Anti anti JJ cord-006870-f5w6fw6q 2709 2 - - JJ cord-006870-f5w6fw6q 2709 3 FXa fxa JJ cord-006870-f5w6fw6q 2709 4 activity activity NN cord-006870-f5w6fw6q 2709 5 was be VBD cord-006870-f5w6fw6q 2709 6 measured measure VBN cord-006870-f5w6fw6q 2709 7 before before IN cord-006870-f5w6fw6q 2709 8 andexanet andexanet NNP cord-006870-f5w6fw6q 2709 9 administration administration NNP cord-006870-f5w6fw6q 2709 10 ( ( -LRB- cord-006870-f5w6fw6q 2709 11 baseline baseline NNP cord-006870-f5w6fw6q 2709 12 ) ) -RRB- cord-006870-f5w6fw6q 2709 13 , , , cord-006870-f5w6fw6q 2709 14 at at IN cord-006870-f5w6fw6q 2709 15 end end NN cord-006870-f5w6fw6q 2709 16 of of IN cord-006870-f5w6fw6q 2709 17 bolus bolus NN cord-006870-f5w6fw6q 2709 18 ( ( -LRB- cord-006870-f5w6fw6q 2709 19 EOB EOB NNP cord-006870-f5w6fw6q 2709 20 ) ) -RRB- cord-006870-f5w6fw6q 2709 21 , , , cord-006870-f5w6fw6q 2709 22 at at IN cord-006870-f5w6fw6q 2709 23 end end NN cord-006870-f5w6fw6q 2709 24 of of IN cord-006870-f5w6fw6q 2709 25 infusion infusion NN cord-006870-f5w6fw6q 2709 26 , , , cord-006870-f5w6fw6q 2709 27 and and CC cord-006870-f5w6fw6q 2709 28 at at IN cord-006870-f5w6fw6q 2709 29 4 4 CD cord-006870-f5w6fw6q 2709 30 , , , cord-006870-f5w6fw6q 2709 31 8 8 CD cord-006870-f5w6fw6q 2709 32 , , , cord-006870-f5w6fw6q 2709 33 and and CC cord-006870-f5w6fw6q 2709 34 12 12 CD cord-006870-f5w6fw6q 2709 35 hours hour NNS cord-006870-f5w6fw6q 2709 36 after after IN cord-006870-f5w6fw6q 2709 37 infusion infusion NN cord-006870-f5w6fw6q 2709 38 . . . cord-006870-f5w6fw6q 2710 1 The the DT cord-006870-f5w6fw6q 2710 2 relationship relationship NN cord-006870-f5w6fw6q 2710 3 between between IN cord-006870-f5w6fw6q 2710 4 baseline baseline JJ cord-006870-f5w6fw6q 2710 5 anti anti JJ cord-006870-f5w6fw6q 2710 6 - - JJ cord-006870-f5w6fw6q 2710 7 FXa fxa JJ cord-006870-f5w6fw6q 2710 8 activity activity NN cord-006870-f5w6fw6q 2710 9 and and CC cord-006870-f5w6fw6q 2710 10 reversal reversal NN cord-006870-f5w6fw6q 2710 11 in in IN cord-006870-f5w6fw6q 2710 12 healthy healthy JJ cord-006870-f5w6fw6q 2710 13 subjects subject NNS cord-006870-f5w6fw6q 2710 14 was be VBD cord-006870-f5w6fw6q 2710 15 derived derive VBN cord-006870-f5w6fw6q 2710 16 from from IN cord-006870-f5w6fw6q 2710 17 the the DT cord-006870-f5w6fw6q 2710 18 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2710 19 / / SYM cord-006870-f5w6fw6q 2710 20 pharmacodynamic pharmacodynamic JJ cord-006870-f5w6fw6q 2710 21 model model NN cord-006870-f5w6fw6q 2710 22 and and CC cord-006870-f5w6fw6q 2710 23 used use VBD cord-006870-f5w6fw6q 2710 24 to to TO cord-006870-f5w6fw6q 2710 25 predict predict VB cord-006870-f5w6fw6q 2710 26 percent percent NN cord-006870-f5w6fw6q 2710 27 reversal reversal NN cord-006870-f5w6fw6q 2710 28 for for IN cord-006870-f5w6fw6q 2710 29 patients patient NNS cord-006870-f5w6fw6q 2710 30 with with IN cord-006870-f5w6fw6q 2710 31 acute acute JJ cord-006870-f5w6fw6q 2710 32 major major JJ cord-006870-f5w6fw6q 2710 33 bleeding bleeding NN cord-006870-f5w6fw6q 2710 34 . . . cord-006870-f5w6fw6q 2711 1 From from IN cord-006870-f5w6fw6q 2711 2 the the DT cord-006870-f5w6fw6q 2711 3 first first JJ cord-006870-f5w6fw6q 2711 4 interim interim JJ cord-006870-f5w6fw6q 2711 5 analysis analysis NN cord-006870-f5w6fw6q 2711 6 of of IN cord-006870-f5w6fw6q 2711 7 ANNEXA-4 ANNEXA-4 NNP cord-006870-f5w6fw6q 2711 8 , , , cord-006870-f5w6fw6q 2711 9 73 73 CD cord-006870-f5w6fw6q 2711 10 patients patient NNS cord-006870-f5w6fw6q 2711 11 ( ( -LRB- cord-006870-f5w6fw6q 2711 12 apixaban apixaban NNP cord-006870-f5w6fw6q 2711 13 , , , cord-006870-f5w6fw6q 2711 14 n=39 n=39 NNP cord-006870-f5w6fw6q 2711 15 ; ; : cord-006870-f5w6fw6q 2711 16 rivaroxaban rivaroxaban NNP cord-006870-f5w6fw6q 2711 17 , , , cord-006870-f5w6fw6q 2711 18 n=34 n=34 NNP cord-006870-f5w6fw6q 2711 19 ) ) -RRB- cord-006870-f5w6fw6q 2711 20 had have VBD cord-006870-f5w6fw6q 2711 21 plasma plasma NN cord-006870-f5w6fw6q 2711 22 levels level NNS cord-006870-f5w6fw6q 2711 23 available available JJ cord-006870-f5w6fw6q 2711 24 for for IN cord-006870-f5w6fw6q 2711 25 model model NN cord-006870-f5w6fw6q 2711 26 qualification qualification NN cord-006870-f5w6fw6q 2711 27 , , , cord-006870-f5w6fw6q 2711 28 although although IN cord-006870-f5w6fw6q 2711 29 7 7 CD cord-006870-f5w6fw6q 2711 30 did do VBD cord-006870-f5w6fw6q 2711 31 not not RB cord-006870-f5w6fw6q 2711 32 meet meet VB cord-006870-f5w6fw6q 2711 33 criteria criterion NNS cord-006870-f5w6fw6q 2711 34 for for IN cord-006870-f5w6fw6q 2711 35 inclusion inclusion NN cord-006870-f5w6fw6q 2711 36 into into IN cord-006870-f5w6fw6q 2711 37 safety safety NN cord-006870-f5w6fw6q 2711 38 and and CC cord-006870-f5w6fw6q 2711 39 27 27 CD cord-006870-f5w6fw6q 2711 40 did do VBD cord-006870-f5w6fw6q 2711 41 not not RB cord-006870-f5w6fw6q 2711 42 meet meet VB cord-006870-f5w6fw6q 2711 43 criteria criterion NNS cord-006870-f5w6fw6q 2711 44 for for IN cord-006870-f5w6fw6q 2711 45 efficacy efficacy NN cord-006870-f5w6fw6q 2711 46 analysis analysis NN cord-006870-f5w6fw6q 2711 47 . . . cord-006870-f5w6fw6q 2712 1 The the DT cord-006870-f5w6fw6q 2712 2 mean mean NN cord-006870-f5w6fw6q 2712 3 observed observe VBD cord-006870-f5w6fw6q 2712 4 percent percent NN cord-006870-f5w6fw6q 2712 5 reversal reversal NN cord-006870-f5w6fw6q 2712 6 of of IN cord-006870-f5w6fw6q 2712 7 anti anti JJ cord-006870-f5w6fw6q 2712 8 - - JJ cord-006870-f5w6fw6q 2712 9 FXa fxa JJ cord-006870-f5w6fw6q 2712 10 activity activity NN cord-006870-f5w6fw6q 2712 11 for for IN cord-006870-f5w6fw6q 2712 12 rivaroxaban rivaroxaban NNP cord-006870-f5w6fw6q 2712 13 and and CC cord-006870-f5w6fw6q 2712 14 apixaban apixaban NNP cord-006870-f5w6fw6q 2712 15 was be VBD cord-006870-f5w6fw6q 2712 16 well well RB cord-006870-f5w6fw6q 2712 17 predicted predict VBN cord-006870-f5w6fw6q 2712 18 by by IN cord-006870-f5w6fw6q 2712 19 the the DT cord-006870-f5w6fw6q 2712 20 healthy healthy JJ cord-006870-f5w6fw6q 2712 21 subject subject JJ cord-006870-f5w6fw6q 2712 22 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2712 23 / / SYM cord-006870-f5w6fw6q 2712 24 pharmacodynamic pharmacodynamic JJ cord-006870-f5w6fw6q 2712 25 model model NN cord-006870-f5w6fw6q 2712 26 ; ; : cord-006870-f5w6fw6q 2712 27 the the DT cord-006870-f5w6fw6q 2712 28 point point NN cord-006870-f5w6fw6q 2712 29 estimates estimate NNS cord-006870-f5w6fw6q 2712 30 fell fall VBD cord-006870-f5w6fw6q 2712 31 within within IN cord-006870-f5w6fw6q 2712 32 the the DT cord-006870-f5w6fw6q 2712 33 90 90 CD cord-006870-f5w6fw6q 2712 34 % % NN cord-006870-f5w6fw6q 2712 35 confidence confidence NN cord-006870-f5w6fw6q 2712 36 intervals interval NNS cord-006870-f5w6fw6q 2712 37 of of IN cord-006870-f5w6fw6q 2712 38 predicted predict VBN cord-006870-f5w6fw6q 2712 39 values value NNS cord-006870-f5w6fw6q 2712 40 . . . cord-006870-f5w6fw6q 2713 1 The the DT cord-006870-f5w6fw6q 2713 2 percent percent NN cord-006870-f5w6fw6q 2713 3 reversal reversal NN cord-006870-f5w6fw6q 2713 4 at at IN cord-006870-f5w6fw6q 2713 5 EOB EOB NNP cord-006870-f5w6fw6q 2713 6 for for IN cord-006870-f5w6fw6q 2713 7 rivaroxaban rivaroxaban NNP cord-006870-f5w6fw6q 2713 8 and and CC cord-006870-f5w6fw6q 2713 9 apixaban apixaban NNP cord-006870-f5w6fw6q 2713 10 were be VBD cord-006870-f5w6fw6q 2713 11 74.4 74.4 CD cord-006870-f5w6fw6q 2713 12 [ [ -LRB- cord-006870-f5w6fw6q 2713 13 58.3 58.3 CD cord-006870-f5w6fw6q 2713 14 - - HYPH cord-006870-f5w6fw6q 2713 15 90.7 90.7 CD cord-006870-f5w6fw6q 2713 16 ] ] -RRB- cord-006870-f5w6fw6q 2713 17 and and CC cord-006870-f5w6fw6q 2713 18 83.9 83.9 CD cord-006870-f5w6fw6q 2713 19 [ [ -LRB- cord-006870-f5w6fw6q 2713 20 75.3 75.3 CD cord-006870-f5w6fw6q 2713 21 - - HYPH cord-006870-f5w6fw6q 2713 22 92.5 92.5 CD cord-006870-f5w6fw6q 2713 23 ] ] -RRB- cord-006870-f5w6fw6q 2713 24 , , , cord-006870-f5w6fw6q 2713 25 compared compare VBN cord-006870-f5w6fw6q 2713 26 with with IN cord-006870-f5w6fw6q 2713 27 76.3 76.3 CD cord-006870-f5w6fw6q 2713 28 and and CC cord-006870-f5w6fw6q 2713 29 84.1 84.1 CD cord-006870-f5w6fw6q 2713 30 predicted predict VBN cord-006870-f5w6fw6q 2713 31 by by IN cord-006870-f5w6fw6q 2713 32 the the DT cord-006870-f5w6fw6q 2713 33 model model NN cord-006870-f5w6fw6q 2713 34 . . . cord-006870-f5w6fw6q 2714 1 The the DT cord-006870-f5w6fw6q 2714 2 predicted predict VBN cord-006870-f5w6fw6q 2714 3 reversal reversal NN cord-006870-f5w6fw6q 2714 4 closely closely RB cord-006870-f5w6fw6q 2714 5 fit fit VBD cord-006870-f5w6fw6q 2714 6 the the DT cord-006870-f5w6fw6q 2714 7 observed observed JJ cord-006870-f5w6fw6q 2714 8 confidence confidence NN cord-006870-f5w6fw6q 2714 9 intervals interval NNS cord-006870-f5w6fw6q 2714 10 through through IN cord-006870-f5w6fw6q 2714 11 the the DT cord-006870-f5w6fw6q 2714 12 first first JJ cord-006870-f5w6fw6q 2714 13 4 4 CD cord-006870-f5w6fw6q 2714 14 hours hour NNS cord-006870-f5w6fw6q 2714 15 for for IN cord-006870-f5w6fw6q 2714 16 rivaroxaban rivaroxaban NN cord-006870-f5w6fw6q 2714 17 and and CC cord-006870-f5w6fw6q 2714 18 apixaban apixaban NNP cord-006870-f5w6fw6q 2714 19 , , , cord-006870-f5w6fw6q 2714 20 and and CC cord-006870-f5w6fw6q 2714 21 extended extend VBD cord-006870-f5w6fw6q 2714 22 through through IN cord-006870-f5w6fw6q 2714 23 all all DT cord-006870-f5w6fw6q 2714 24 evaluated evaluate VBN cord-006870-f5w6fw6q 2714 25 time time NN cord-006870-f5w6fw6q 2714 26 points point NNS cord-006870-f5w6fw6q 2714 27 for for IN cord-006870-f5w6fw6q 2714 28 rivaroxaban rivaroxaban NN cord-006870-f5w6fw6q 2714 29 and and CC cord-006870-f5w6fw6q 2714 30 slightly slightly RB cord-006870-f5w6fw6q 2714 31 outside outside RB cord-006870-f5w6fw6q 2714 32 of of IN cord-006870-f5w6fw6q 2714 33 post-4-hour post-4-hour NNP cord-006870-f5w6fw6q 2714 34 time time NN cord-006870-f5w6fw6q 2714 35 points point NNS cord-006870-f5w6fw6q 2714 36 for for IN cord-006870-f5w6fw6q 2714 37 apixaban apixaban NNP cord-006870-f5w6fw6q 2714 38 , , , cord-006870-f5w6fw6q 2714 39 possibly possibly RB cord-006870-f5w6fw6q 2714 40 due due IN cord-006870-f5w6fw6q 2714 41 to to IN cord-006870-f5w6fw6q 2714 42 higher high JJR cord-006870-f5w6fw6q 2714 43 baseline baseline JJ cord-006870-f5w6fw6q 2714 44 anti anti JJ cord-006870-f5w6fw6q 2714 45 - - JJ cord-006870-f5w6fw6q 2714 46 FXa fxa JJ cord-006870-f5w6fw6q 2714 47 activity activity NN cord-006870-f5w6fw6q 2714 48 levels level NNS cord-006870-f5w6fw6q 2714 49 for for IN cord-006870-f5w6fw6q 2714 50 apixaban apixaban NNP cord-006870-f5w6fw6q 2714 51 . . . cord-006870-f5w6fw6q 2715 1 The the DT cord-006870-f5w6fw6q 2715 2 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 2715 3 / / SYM cord-006870-f5w6fw6q 2715 4 pharmacodynamic pharmacodynamic JJ cord-006870-f5w6fw6q 2715 5 model model NN cord-006870-f5w6fw6q 2715 6 in in IN cord-006870-f5w6fw6q 2715 7 healthy healthy JJ cord-006870-f5w6fw6q 2715 8 subjects subject NNS cord-006870-f5w6fw6q 2715 9 closely closely RB cord-006870-f5w6fw6q 2715 10 predicted predict VBD cord-006870-f5w6fw6q 2715 11 the the DT cord-006870-f5w6fw6q 2715 12 extent extent NN cord-006870-f5w6fw6q 2715 13 of of IN cord-006870-f5w6fw6q 2715 14 reversal reversal NN cord-006870-f5w6fw6q 2715 15 of of IN cord-006870-f5w6fw6q 2715 16 anti anti JJ cord-006870-f5w6fw6q 2715 17 - - JJ cord-006870-f5w6fw6q 2715 18 FXa fxa JJ cord-006870-f5w6fw6q 2715 19 activity activity NN cord-006870-f5w6fw6q 2715 20 for for IN cord-006870-f5w6fw6q 2715 21 apixaban apixaban NNP cord-006870-f5w6fw6q 2715 22 and and CC cord-006870-f5w6fw6q 2715 23 rivaroxaban rivaroxaban VBN cord-006870-f5w6fw6q 2715 24 in in IN cord-006870-f5w6fw6q 2715 25 patients patient NNS cord-006870-f5w6fw6q 2715 26 with with IN cord-006870-f5w6fw6q 2715 27 major major JJ cord-006870-f5w6fw6q 2715 28 bleeding bleeding NN cord-006870-f5w6fw6q 2715 29 . . . cord-006870-f5w6fw6q 2716 1 Risk risk NN cord-006870-f5w6fw6q 2716 2 factors factor NNS cord-006870-f5w6fw6q 2716 3 and and CC cord-006870-f5w6fw6q 2716 4 methods method NNS cord-006870-f5w6fw6q 2716 5 to to TO cord-006870-f5w6fw6q 2716 6 predict predict VB cord-006870-f5w6fw6q 2716 7 extubation extubation NN cord-006870-f5w6fw6q 2716 8 failure failure NN cord-006870-f5w6fw6q 2716 9 are be VBP cord-006870-f5w6fw6q 2716 10 well well RB cord-006870-f5w6fw6q 2716 11 established establish VBN cord-006870-f5w6fw6q 2716 12 for for IN cord-006870-f5w6fw6q 2716 13 patients patient NNS cord-006870-f5w6fw6q 2716 14 in in IN cord-006870-f5w6fw6q 2716 15 Medical medical JJ cord-006870-f5w6fw6q 2716 16 ICUs icu NNS cord-006870-f5w6fw6q 2716 17 and and CC cord-006870-f5w6fw6q 2716 18 Surgical surgical JJ cord-006870-f5w6fw6q 2716 19 ICUs icu NNS cord-006870-f5w6fw6q 2716 20 . . . cord-006870-f5w6fw6q 2717 1 Literature literature NN cord-006870-f5w6fw6q 2717 2 on on IN cord-006870-f5w6fw6q 2717 3 patients patient NNS cord-006870-f5w6fw6q 2717 4 who who WP cord-006870-f5w6fw6q 2717 5 fail fail VBP cord-006870-f5w6fw6q 2717 6 extubations extubation NNS cord-006870-f5w6fw6q 2717 7 in in IN cord-006870-f5w6fw6q 2717 8 Neurological Neurological NNP cord-006870-f5w6fw6q 2717 9 ICUs ICUs NNP cord-006870-f5w6fw6q 2717 10 is be VBZ cord-006870-f5w6fw6q 2717 11 limited limit VBN cord-006870-f5w6fw6q 2717 12 . . . cord-006870-f5w6fw6q 2718 1 The the DT cord-006870-f5w6fw6q 2718 2 intention intention NN cord-006870-f5w6fw6q 2718 3 of of IN cord-006870-f5w6fw6q 2718 4 this this DT cord-006870-f5w6fw6q 2718 5 study study NN cord-006870-f5w6fw6q 2718 6 was be VBD cord-006870-f5w6fw6q 2718 7 to to TO cord-006870-f5w6fw6q 2718 8 collect collect VB cord-006870-f5w6fw6q 2718 9 descriptive descriptive JJ cord-006870-f5w6fw6q 2718 10 information information NN cord-006870-f5w6fw6q 2718 11 from from IN cord-006870-f5w6fw6q 2718 12 patients patient NNS cord-006870-f5w6fw6q 2718 13 with with IN cord-006870-f5w6fw6q 2718 14 neurological neurological JJ cord-006870-f5w6fw6q 2718 15 injuries injury NNS cord-006870-f5w6fw6q 2718 16 who who WP cord-006870-f5w6fw6q 2718 17 failed fail VBD cord-006870-f5w6fw6q 2718 18 liberation liberation NN cord-006870-f5w6fw6q 2718 19 from from IN cord-006870-f5w6fw6q 2718 20 mechanical mechanical JJ cord-006870-f5w6fw6q 2718 21 ventilation ventilation NN cord-006870-f5w6fw6q 2718 22 . . . cord-006870-f5w6fw6q 2719 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 2719 2 review review NN cord-006870-f5w6fw6q 2719 3 of of IN cord-006870-f5w6fw6q 2719 4 all all DT cord-006870-f5w6fw6q 2719 5 patients patient NNS cord-006870-f5w6fw6q 2719 6 with with IN cord-006870-f5w6fw6q 2719 7 acute acute JJ cord-006870-f5w6fw6q 2719 8 neurological neurological JJ cord-006870-f5w6fw6q 2719 9 injury injury NN cord-006870-f5w6fw6q 2719 10 who who WP cord-006870-f5w6fw6q 2719 11 were be VBD cord-006870-f5w6fw6q 2719 12 admitted admit VBN cord-006870-f5w6fw6q 2719 13 to to IN cord-006870-f5w6fw6q 2719 14 our -PRON- PRP$ cord-006870-f5w6fw6q 2719 15 Neuro Neuro NNP cord-006870-f5w6fw6q 2719 16 ICU ICU NNP cord-006870-f5w6fw6q 2719 17 and and CC cord-006870-f5w6fw6q 2719 18 who who WP cord-006870-f5w6fw6q 2719 19 required require VBD cord-006870-f5w6fw6q 2719 20 reintubation reintubation NN cord-006870-f5w6fw6q 2719 21 within within IN cord-006870-f5w6fw6q 2719 22 72 72 CD cord-006870-f5w6fw6q 2719 23 hours hour NNS cord-006870-f5w6fw6q 2719 24 of of IN cord-006870-f5w6fw6q 2719 25 discontinuation discontinuation NN cord-006870-f5w6fw6q 2719 26 of of IN cord-006870-f5w6fw6q 2719 27 mechanical mechanical JJ cord-006870-f5w6fw6q 2719 28 ventilation ventilation NN cord-006870-f5w6fw6q 2719 29 between between IN cord-006870-f5w6fw6q 2719 30 January January NNP cord-006870-f5w6fw6q 2719 31 2012 2012 CD cord-006870-f5w6fw6q 2719 32 -February -february SYM cord-006870-f5w6fw6q 2719 33 2017 2017 CD cord-006870-f5w6fw6q 2719 34 . . . cord-006870-f5w6fw6q 2720 1 We -PRON- PRP cord-006870-f5w6fw6q 2720 2 identified identify VBD cord-006870-f5w6fw6q 2720 3 60 60 CD cord-006870-f5w6fw6q 2720 4 patients patient NNS cord-006870-f5w6fw6q 2720 5 intubated intubate VBN cord-006870-f5w6fw6q 2720 6 primarily primarily RB cord-006870-f5w6fw6q 2720 7 due due JJ cord-006870-f5w6fw6q 2720 8 to to IN cord-006870-f5w6fw6q 2720 9 neurological neurological JJ cord-006870-f5w6fw6q 2720 10 pathology pathology NN cord-006870-f5w6fw6q 2720 11 who who WP cord-006870-f5w6fw6q 2720 12 required require VBD cord-006870-f5w6fw6q 2720 13 reintubation reintubation NN cord-006870-f5w6fw6q 2720 14 within within IN cord-006870-f5w6fw6q 2720 15 72 72 CD cord-006870-f5w6fw6q 2720 16 hours hour NNS cord-006870-f5w6fw6q 2720 17 after after IN cord-006870-f5w6fw6q 2720 18 initial initial JJ cord-006870-f5w6fw6q 2720 19 extubation extubation NN cord-006870-f5w6fw6q 2720 20 over over IN cord-006870-f5w6fw6q 2720 21 a a DT cord-006870-f5w6fw6q 2720 22 5-year 5-year CD cord-006870-f5w6fw6q 2720 23 study study NN cord-006870-f5w6fw6q 2720 24 period period NN cord-006870-f5w6fw6q 2720 25 . . . cord-006870-f5w6fw6q 2721 1 The the DT cord-006870-f5w6fw6q 2721 2 majority majority NN cord-006870-f5w6fw6q 2721 3 of of IN cord-006870-f5w6fw6q 2721 4 reintubated reintubated JJ cord-006870-f5w6fw6q 2721 5 patients patient NNS cord-006870-f5w6fw6q 2721 6 ( ( -LRB- cord-006870-f5w6fw6q 2721 7 n=43 n=43 NNP cord-006870-f5w6fw6q 2721 8 ; ; : cord-006870-f5w6fw6q 2721 9 71.7 71.7 CD cord-006870-f5w6fw6q 2721 10 % % NN cord-006870-f5w6fw6q 2721 11 , , , cord-006870-f5w6fw6q 2721 12 ) ) -RRB- cord-006870-f5w6fw6q 2721 13 had have VBD cord-006870-f5w6fw6q 2721 14 a a DT cord-006870-f5w6fw6q 2721 15 positive positive JJ cord-006870-f5w6fw6q 2721 16 fluid fluid JJ cord-006870-f5w6fw6q 2721 17 balance balance NN cord-006870-f5w6fw6q 2721 18 prior prior RB cord-006870-f5w6fw6q 2721 19 to to IN cord-006870-f5w6fw6q 2721 20 failed fail VBN cord-006870-f5w6fw6q 2721 21 extubation extubation NN cord-006870-f5w6fw6q 2721 22 . . . cord-006870-f5w6fw6q 2722 1 Twenty twenty CD cord-006870-f5w6fw6q 2722 2 - - HYPH cord-006870-f5w6fw6q 2722 3 six six CD cord-006870-f5w6fw6q 2722 4 of of IN cord-006870-f5w6fw6q 2722 5 the the DT cord-006870-f5w6fw6q 2722 6 reintubated reintubated JJ cord-006870-f5w6fw6q 2722 7 patients patient NNS cord-006870-f5w6fw6q 2722 8 had have VBD cord-006870-f5w6fw6q 2722 9 a a DT cord-006870-f5w6fw6q 2722 10 concurrent concurrent JJ cord-006870-f5w6fw6q 2722 11 underlying underlie VBG cord-006870-f5w6fw6q 2722 12 chronic chronic JJ cord-006870-f5w6fw6q 2722 13 cardiac cardiac NN cord-006870-f5w6fw6q 2722 14 and/or and/or CC cord-006870-f5w6fw6q 2722 15 pulmonary pulmonary JJ cord-006870-f5w6fw6q 2722 16 disease disease NN cord-006870-f5w6fw6q 2722 17 . . . cord-006870-f5w6fw6q 2723 1 Five five CD cord-006870-f5w6fw6q 2723 2 patients patient NNS cord-006870-f5w6fw6q 2723 3 were be VBD cord-006870-f5w6fw6q 2723 4 placed place VBN cord-006870-f5w6fw6q 2723 5 on on IN cord-006870-f5w6fw6q 2723 6 noninvasive noninvasive JJ cord-006870-f5w6fw6q 2723 7 ventilation ventilation NN cord-006870-f5w6fw6q 2723 8 post post NN cord-006870-f5w6fw6q 2723 9 extubation extubation NN cord-006870-f5w6fw6q 2723 10 . . . cord-006870-f5w6fw6q 2724 1 Low low JJ cord-006870-f5w6fw6q 2724 2 Glascow Glascow NNP cord-006870-f5w6fw6q 2724 3 Coma Coma NNP cord-006870-f5w6fw6q 2724 4 Scale scale NN cord-006870-f5w6fw6q 2724 5 and and CC cord-006870-f5w6fw6q 2724 6 absence absence NN cord-006870-f5w6fw6q 2724 7 of of IN cord-006870-f5w6fw6q 2724 8 basic basic JJ cord-006870-f5w6fw6q 2724 9 brainstem brainstem NN cord-006870-f5w6fw6q 2724 10 functions function NNS cord-006870-f5w6fw6q 2724 11 ( ( -LRB- cord-006870-f5w6fw6q 2724 12 gag gag NN cord-006870-f5w6fw6q 2724 13 and and CC cord-006870-f5w6fw6q 2724 14 cough cough NN cord-006870-f5w6fw6q 2724 15 reflexes reflex NNS cord-006870-f5w6fw6q 2724 16 ) ) -RRB- cord-006870-f5w6fw6q 2724 17 was be VBD cord-006870-f5w6fw6q 2724 18 only only RB cord-006870-f5w6fw6q 2724 19 minimally minimally RB cord-006870-f5w6fw6q 2724 20 predictive predictive JJ cord-006870-f5w6fw6q 2724 21 of of IN cord-006870-f5w6fw6q 2724 22 extubation extubation NN cord-006870-f5w6fw6q 2724 23 failure failure NN cord-006870-f5w6fw6q 2724 24 . . . cord-006870-f5w6fw6q 2725 1 Most Most JJS cord-006870-f5w6fw6q 2725 2 of of IN cord-006870-f5w6fw6q 2725 3 our -PRON- PRP$ cord-006870-f5w6fw6q 2725 4 reintubated reintubated JJ cord-006870-f5w6fw6q 2725 5 patients patient NNS cord-006870-f5w6fw6q 2725 6 did do VBD cord-006870-f5w6fw6q 2725 7 not not RB cord-006870-f5w6fw6q 2725 8 have have VB cord-006870-f5w6fw6q 2725 9 significant significant JJ cord-006870-f5w6fw6q 2725 10 supratentorial supratentorial JJ cord-006870-f5w6fw6q 2725 11 midline midline NN cord-006870-f5w6fw6q 2725 12 shift shift NN cord-006870-f5w6fw6q 2725 13 nor nor CC cord-006870-f5w6fw6q 2725 14 an an DT cord-006870-f5w6fw6q 2725 15 insult insult NN cord-006870-f5w6fw6q 2725 16 to to IN cord-006870-f5w6fw6q 2725 17 the the DT cord-006870-f5w6fw6q 2725 18 posterior posterior JJ cord-006870-f5w6fw6q 2725 19 circulation circulation NN cord-006870-f5w6fw6q 2725 20 or or CC cord-006870-f5w6fw6q 2725 21 dominant dominant JJ cord-006870-f5w6fw6q 2725 22 hemisphere hemisphere NN cord-006870-f5w6fw6q 2725 23 . . . cord-006870-f5w6fw6q 2726 1 In in IN cord-006870-f5w6fw6q 2726 2 patients patient NNS cord-006870-f5w6fw6q 2726 3 with with IN cord-006870-f5w6fw6q 2726 4 primary primary JJ cord-006870-f5w6fw6q 2726 5 brain brain NN cord-006870-f5w6fw6q 2726 6 injury injury NN cord-006870-f5w6fw6q 2726 7 who who WP cord-006870-f5w6fw6q 2726 8 required require VBD cord-006870-f5w6fw6q 2726 9 reintubation reintubation NN cord-006870-f5w6fw6q 2726 10 , , , cord-006870-f5w6fw6q 2726 11 a a DT cord-006870-f5w6fw6q 2726 12 positive positive JJ cord-006870-f5w6fw6q 2726 13 fluid fluid JJ cord-006870-f5w6fw6q 2726 14 balance balance NN cord-006870-f5w6fw6q 2726 15 prior prior RB cord-006870-f5w6fw6q 2726 16 to to IN cord-006870-f5w6fw6q 2726 17 extubation extubation NN cord-006870-f5w6fw6q 2726 18 may may MD cord-006870-f5w6fw6q 2726 19 confer confer VB cord-006870-f5w6fw6q 2726 20 a a DT cord-006870-f5w6fw6q 2726 21 lower low JJR cord-006870-f5w6fw6q 2726 22 rate rate NN cord-006870-f5w6fw6q 2726 23 of of IN cord-006870-f5w6fw6q 2726 24 successful successful JJ cord-006870-f5w6fw6q 2726 25 extubation extubation NN cord-006870-f5w6fw6q 2726 26 . . . cord-006870-f5w6fw6q 2727 1 Lesion lesion NN cord-006870-f5w6fw6q 2727 2 location location NN cord-006870-f5w6fw6q 2727 3 and and CC cord-006870-f5w6fw6q 2727 4 supratentorial supratentorial NNP cord-006870-f5w6fw6q 2727 5 midline midline NNP cord-006870-f5w6fw6q 2727 6 shift shift NN cord-006870-f5w6fw6q 2727 7 may may MD cord-006870-f5w6fw6q 2727 8 not not RB cord-006870-f5w6fw6q 2727 9 be be VB cord-006870-f5w6fw6q 2727 10 tightly tightly RB cord-006870-f5w6fw6q 2727 11 associated associate VBN cord-006870-f5w6fw6q 2727 12 with with IN cord-006870-f5w6fw6q 2727 13 extubation extubation NN cord-006870-f5w6fw6q 2727 14 success success NN cord-006870-f5w6fw6q 2727 15 . . . cord-006870-f5w6fw6q 2728 1 Overall overall RB cord-006870-f5w6fw6q 2728 2 , , , cord-006870-f5w6fw6q 2728 3 our -PRON- PRP$ cord-006870-f5w6fw6q 2728 4 reintubation reintubation NN cord-006870-f5w6fw6q 2728 5 rate rate NN cord-006870-f5w6fw6q 2728 6 is be VBZ cord-006870-f5w6fw6q 2728 7 quite quite RB cord-006870-f5w6fw6q 2728 8 low low JJ cord-006870-f5w6fw6q 2728 9 . . . cord-006870-f5w6fw6q 2729 1 Early early JJ cord-006870-f5w6fw6q 2729 2 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 2729 3 may may MD cord-006870-f5w6fw6q 2729 4 play play VB cord-006870-f5w6fw6q 2729 5 a a DT cord-006870-f5w6fw6q 2729 6 small small JJ cord-006870-f5w6fw6q 2729 7 but but CC cord-006870-f5w6fw6q 2729 8 significant significant JJ cord-006870-f5w6fw6q 2729 9 role role NN cord-006870-f5w6fw6q 2729 10 in in IN cord-006870-f5w6fw6q 2729 11 the the DT cord-006870-f5w6fw6q 2729 12 low low JJ cord-006870-f5w6fw6q 2729 13 rate rate NN cord-006870-f5w6fw6q 2729 14 of of IN cord-006870-f5w6fw6q 2729 15 reintubation reintubation NN cord-006870-f5w6fw6q 2729 16 . . . cord-006870-f5w6fw6q 2730 1 Further further JJ cord-006870-f5w6fw6q 2730 2 studies study NNS cord-006870-f5w6fw6q 2730 3 may may MD cord-006870-f5w6fw6q 2730 4 be be VB cord-006870-f5w6fw6q 2730 5 useful useful JJ cord-006870-f5w6fw6q 2730 6 in in IN cord-006870-f5w6fw6q 2730 7 creating create VBG cord-006870-f5w6fw6q 2730 8 a a DT cord-006870-f5w6fw6q 2730 9 scoring scoring NN cord-006870-f5w6fw6q 2730 10 system system NN cord-006870-f5w6fw6q 2730 11 to to TO cord-006870-f5w6fw6q 2730 12 identify identify VB cord-006870-f5w6fw6q 2730 13 the the DT cord-006870-f5w6fw6q 2730 14 likelihood likelihood NN cord-006870-f5w6fw6q 2730 15 of of IN cord-006870-f5w6fw6q 2730 16 extubation extubation NN cord-006870-f5w6fw6q 2730 17 success success NN cord-006870-f5w6fw6q 2730 18 in in IN cord-006870-f5w6fw6q 2730 19 patients patient NNS cord-006870-f5w6fw6q 2730 20 with with IN cord-006870-f5w6fw6q 2730 21 neurological neurological JJ cord-006870-f5w6fw6q 2730 22 injury injury NN cord-006870-f5w6fw6q 2730 23 . . . cord-006870-f5w6fw6q 2731 1 Surgical surgical JJ cord-006870-f5w6fw6q 2731 2 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2731 3 guidelines guideline NNS cord-006870-f5w6fw6q 2731 4 for for IN cord-006870-f5w6fw6q 2731 5 EVD EVD NNP cord-006870-f5w6fw6q 2731 6 insertion insertion NN cord-006870-f5w6fw6q 2731 7 recommend recommend VBP cord-006870-f5w6fw6q 2731 8 peri peri JJ cord-006870-f5w6fw6q 2731 9 - - JJ cord-006870-f5w6fw6q 2731 10 procedural procedural JJ cord-006870-f5w6fw6q 2731 11 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2731 12 rather rather RB cord-006870-f5w6fw6q 2731 13 than than IN cord-006870-f5w6fw6q 2731 14 prolonged prolong VBN cord-006870-f5w6fw6q 2731 15 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2731 16 administration administration NN cord-006870-f5w6fw6q 2731 17 for for IN cord-006870-f5w6fw6q 2731 18 the the DT cord-006870-f5w6fw6q 2731 19 duration duration NN cord-006870-f5w6fw6q 2731 20 of of IN cord-006870-f5w6fw6q 2731 21 EVD EVD NNP cord-006870-f5w6fw6q 2731 22 placement placement NN cord-006870-f5w6fw6q 2731 23 . . . cord-006870-f5w6fw6q 2732 1 Several several JJ cord-006870-f5w6fw6q 2732 2 small small JJ cord-006870-f5w6fw6q 2732 3 studies study NNS cord-006870-f5w6fw6q 2732 4 have have VBP cord-006870-f5w6fw6q 2732 5 shown show VBN cord-006870-f5w6fw6q 2732 6 that that IN cord-006870-f5w6fw6q 2732 7 prolonged prolong VBN cord-006870-f5w6fw6q 2732 8 systemic systemic JJ cord-006870-f5w6fw6q 2732 9 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2732 10 use use NN cord-006870-f5w6fw6q 2732 11 does do VBZ cord-006870-f5w6fw6q 2732 12 not not RB cord-006870-f5w6fw6q 2732 13 reduce reduce VB cord-006870-f5w6fw6q 2732 14 the the DT cord-006870-f5w6fw6q 2732 15 incidence incidence NN cord-006870-f5w6fw6q 2732 16 of of IN cord-006870-f5w6fw6q 2732 17 catheter catheter NN cord-006870-f5w6fw6q 2732 18 related relate VBN cord-006870-f5w6fw6q 2732 19 ventriculitis ventriculitis NN cord-006870-f5w6fw6q 2732 20 . . . cord-006870-f5w6fw6q 2733 1 Prolonged prolonged JJ cord-006870-f5w6fw6q 2733 2 use use NN cord-006870-f5w6fw6q 2733 3 is be VBZ cord-006870-f5w6fw6q 2733 4 also also RB cord-006870-f5w6fw6q 2733 5 associated associate VBN cord-006870-f5w6fw6q 2733 6 with with IN cord-006870-f5w6fw6q 2733 7 a a DT cord-006870-f5w6fw6q 2733 8 higher high JJR cord-006870-f5w6fw6q 2733 9 rate rate NN cord-006870-f5w6fw6q 2733 10 of of IN cord-006870-f5w6fw6q 2733 11 multi multi JJ cord-006870-f5w6fw6q 2733 12 - - JJ cord-006870-f5w6fw6q 2733 13 drug drug JJ cord-006870-f5w6fw6q 2733 14 resistant resistant NN cord-006870-f5w6fw6q 2733 15 ( ( -LRB- cord-006870-f5w6fw6q 2733 16 MDR MDR NNP cord-006870-f5w6fw6q 2733 17 ) ) -RRB- cord-006870-f5w6fw6q 2733 18 infections infection NNS cord-006870-f5w6fw6q 2733 19 . . . cord-006870-f5w6fw6q 2734 1 This this DT cord-006870-f5w6fw6q 2734 2 study study NN cord-006870-f5w6fw6q 2734 3 aims aim VBZ cord-006870-f5w6fw6q 2734 4 to to TO cord-006870-f5w6fw6q 2734 5 show show VB cord-006870-f5w6fw6q 2734 6 that that IN cord-006870-f5w6fw6q 2734 7 prolonged prolong VBD cord-006870-f5w6fw6q 2734 8 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2734 9 administration administration NN cord-006870-f5w6fw6q 2734 10 following follow VBG cord-006870-f5w6fw6q 2734 11 EVD EVD NNP cord-006870-f5w6fw6q 2734 12 insertion insertion NN cord-006870-f5w6fw6q 2734 13 is be VBZ cord-006870-f5w6fw6q 2734 14 potentially potentially RB cord-006870-f5w6fw6q 2734 15 harmful harmful JJ cord-006870-f5w6fw6q 2734 16 . . . cord-006870-f5w6fw6q 2735 1 This this DT cord-006870-f5w6fw6q 2735 2 is be VBZ cord-006870-f5w6fw6q 2735 3 a a DT cord-006870-f5w6fw6q 2735 4 single single JJ cord-006870-f5w6fw6q 2735 5 center center NN cord-006870-f5w6fw6q 2735 6 , , , cord-006870-f5w6fw6q 2735 7 retrospective retrospective JJ cord-006870-f5w6fw6q 2735 8 , , , cord-006870-f5w6fw6q 2735 9 chart chart NN cord-006870-f5w6fw6q 2735 10 review review NN cord-006870-f5w6fw6q 2735 11 . . . cord-006870-f5w6fw6q 2736 1 All all DT cord-006870-f5w6fw6q 2736 2 100 100 CD cord-006870-f5w6fw6q 2736 3 patients patient NNS cord-006870-f5w6fw6q 2736 4 admitted admit VBN cord-006870-f5w6fw6q 2736 5 to to IN cord-006870-f5w6fw6q 2736 6 our -PRON- PRP$ cord-006870-f5w6fw6q 2736 7 hospital hospital NN cord-006870-f5w6fw6q 2736 8 who who WP cord-006870-f5w6fw6q 2736 9 had have VBD cord-006870-f5w6fw6q 2736 10 an an DT cord-006870-f5w6fw6q 2736 11 EVD EVD NNP cord-006870-f5w6fw6q 2736 12 placed place VBN cord-006870-f5w6fw6q 2736 13 from from IN cord-006870-f5w6fw6q 2736 14 January January NNP cord-006870-f5w6fw6q 2736 15 2000 2000 CD cord-006870-f5w6fw6q 2736 16 to to IN cord-006870-f5w6fw6q 2736 17 March March NNP cord-006870-f5w6fw6q 2736 18 2017 2017 CD cord-006870-f5w6fw6q 2736 19 were be VBD cord-006870-f5w6fw6q 2736 20 identified identify VBN cord-006870-f5w6fw6q 2736 21 . . . cord-006870-f5w6fw6q 2737 1 Patients patient NNS cord-006870-f5w6fw6q 2737 2 with with IN cord-006870-f5w6fw6q 2737 3 preceding precede VBG cord-006870-f5w6fw6q 2737 4 infections infection NNS cord-006870-f5w6fw6q 2737 5 , , , cord-006870-f5w6fw6q 2737 6 incomplete incomplete JJ cord-006870-f5w6fw6q 2737 7 data datum NNS cord-006870-f5w6fw6q 2737 8 or or CC cord-006870-f5w6fw6q 2737 9 uncertain uncertain JJ cord-006870-f5w6fw6q 2737 10 infection infection NN cord-006870-f5w6fw6q 2737 11 diagnosis diagnosis NN cord-006870-f5w6fw6q 2737 12 were be VBD cord-006870-f5w6fw6q 2737 13 excluded exclude VBN cord-006870-f5w6fw6q 2737 14 . . . cord-006870-f5w6fw6q 2738 1 Sixty sixty CD cord-006870-f5w6fw6q 2738 2 - - HYPH cord-006870-f5w6fw6q 2738 3 nine nine CD cord-006870-f5w6fw6q 2738 4 patients patient NNS cord-006870-f5w6fw6q 2738 5 were be VBD cord-006870-f5w6fw6q 2738 6 analyzed analyze VBN cord-006870-f5w6fw6q 2738 7 . . . cord-006870-f5w6fw6q 2739 1 Documented document VBN cord-006870-f5w6fw6q 2739 2 variables variable NNS cord-006870-f5w6fw6q 2739 3 included include VBD cord-006870-f5w6fw6q 2739 4 demographics demographic NNS cord-006870-f5w6fw6q 2739 5 , , , cord-006870-f5w6fw6q 2739 6 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 2739 7 , , , cord-006870-f5w6fw6q 2739 8 indications indication NNS cord-006870-f5w6fw6q 2739 9 for for IN cord-006870-f5w6fw6q 2739 10 EVD EVD NNP cord-006870-f5w6fw6q 2739 11 , , , cord-006870-f5w6fw6q 2739 12 duration duration NN cord-006870-f5w6fw6q 2739 13 of of IN cord-006870-f5w6fw6q 2739 14 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2739 15 therapy therapy NN cord-006870-f5w6fw6q 2739 16 , , , cord-006870-f5w6fw6q 2739 17 infections infection NNS cord-006870-f5w6fw6q 2739 18 and and CC cord-006870-f5w6fw6q 2739 19 organisms organism NNS cord-006870-f5w6fw6q 2739 20 ' ' POS cord-006870-f5w6fw6q 2739 21 sensitivities sensitivity NNS cord-006870-f5w6fw6q 2739 22 . . . cord-006870-f5w6fw6q 2740 1 Eight eight CD cord-006870-f5w6fw6q 2740 2 patients patient NNS cord-006870-f5w6fw6q 2740 3 ( ( -LRB- cord-006870-f5w6fw6q 2740 4 12 12 CD cord-006870-f5w6fw6q 2740 5 % % NN cord-006870-f5w6fw6q 2740 6 ) ) -RRB- cord-006870-f5w6fw6q 2740 7 did do VBD cord-006870-f5w6fw6q 2740 8 not not RB cord-006870-f5w6fw6q 2740 9 receive receive VB cord-006870-f5w6fw6q 2740 10 any any DT cord-006870-f5w6fw6q 2740 11 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2740 12 therapy therapy NN cord-006870-f5w6fw6q 2740 13 ; ; : cord-006870-f5w6fw6q 2740 14 the the DT cord-006870-f5w6fw6q 2740 15 rest rest NN cord-006870-f5w6fw6q 2740 16 received receive VBD cord-006870-f5w6fw6q 2740 17 Cefazolin Cefazolin NNP cord-006870-f5w6fw6q 2740 18 following follow VBG cord-006870-f5w6fw6q 2740 19 EVD EVD NNP cord-006870-f5w6fw6q 2740 20 insertion insertion NN cord-006870-f5w6fw6q 2740 21 . . . cord-006870-f5w6fw6q 2741 1 Infections infection NNS cord-006870-f5w6fw6q 2741 2 occurred occur VBD cord-006870-f5w6fw6q 2741 3 in in IN cord-006870-f5w6fw6q 2741 4 22 22 CD cord-006870-f5w6fw6q 2741 5 of of IN cord-006870-f5w6fw6q 2741 6 69 69 CD cord-006870-f5w6fw6q 2741 7 ( ( -LRB- cord-006870-f5w6fw6q 2741 8 32 32 CD cord-006870-f5w6fw6q 2741 9 % % NN cord-006870-f5w6fw6q 2741 10 ) ) -RRB- cord-006870-f5w6fw6q 2741 11 patients patient NNS cord-006870-f5w6fw6q 2741 12 ; ; : cord-006870-f5w6fw6q 2741 13 13 13 CD cord-006870-f5w6fw6q 2741 14 of of IN cord-006870-f5w6fw6q 2741 15 22 22 CD cord-006870-f5w6fw6q 2741 16 ( ( -LRB- cord-006870-f5w6fw6q 2741 17 59 59 CD cord-006870-f5w6fw6q 2741 18 % % NN cord-006870-f5w6fw6q 2741 19 ) ) -RRB- cord-006870-f5w6fw6q 2741 20 were be VBD cord-006870-f5w6fw6q 2741 21 MDR MDR NNP cord-006870-f5w6fw6q 2741 22 bacteria bacteria NNS cord-006870-f5w6fw6q 2741 23 . . . cord-006870-f5w6fw6q 2742 1 Ventriculitis Ventriculitis NNP cord-006870-f5w6fw6q 2742 2 occurred occur VBD cord-006870-f5w6fw6q 2742 3 in in IN cord-006870-f5w6fw6q 2742 4 4 4 CD cord-006870-f5w6fw6q 2742 5 ( ( -LRB- cord-006870-f5w6fw6q 2742 6 6 6 CD cord-006870-f5w6fw6q 2742 7 % % NN cord-006870-f5w6fw6q 2742 8 ) ) -RRB- cord-006870-f5w6fw6q 2742 9 patients patient NNS cord-006870-f5w6fw6q 2742 10 , , , cord-006870-f5w6fw6q 2742 11 and and CC cord-006870-f5w6fw6q 2742 12 2 2 CD cord-006870-f5w6fw6q 2742 13 of of IN cord-006870-f5w6fw6q 2742 14 these these DT cord-006870-f5w6fw6q 2742 15 were be VBD cord-006870-f5w6fw6q 2742 16 resistant resistant JJ cord-006870-f5w6fw6q 2742 17 to to IN cord-006870-f5w6fw6q 2742 18 Cefazolin Cefazolin NNP cord-006870-f5w6fw6q 2742 19 ( ( -LRB- cord-006870-f5w6fw6q 2742 20 MDR MDR NNP cord-006870-f5w6fw6q 2742 21 ) ) -RRB- cord-006870-f5w6fw6q 2742 22 . . . cord-006870-f5w6fw6q 2743 1 Ventriculitis Ventriculitis NNP cord-006870-f5w6fw6q 2743 2 was be VBD cord-006870-f5w6fw6q 2743 3 not not RB cord-006870-f5w6fw6q 2743 4 associated associate VBN cord-006870-f5w6fw6q 2743 5 with with IN cord-006870-f5w6fw6q 2743 6 the the DT cord-006870-f5w6fw6q 2743 7 use use NN cord-006870-f5w6fw6q 2743 8 or or CC cord-006870-f5w6fw6q 2743 9 duration duration NN cord-006870-f5w6fw6q 2743 10 of of IN cord-006870-f5w6fw6q 2743 11 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2743 12 therapy therapy NN cord-006870-f5w6fw6q 2743 13 . . . cord-006870-f5w6fw6q 2744 1 Graphical graphical JJ cord-006870-f5w6fw6q 2744 2 analysis analysis NN cord-006870-f5w6fw6q 2744 3 showed show VBD cord-006870-f5w6fw6q 2744 4 that that IN cord-006870-f5w6fw6q 2744 5 the the DT cord-006870-f5w6fw6q 2744 6 probability probability NN cord-006870-f5w6fw6q 2744 7 of of IN cord-006870-f5w6fw6q 2744 8 any any DT cord-006870-f5w6fw6q 2744 9 infection infection NN cord-006870-f5w6fw6q 2744 10 decreased decrease VBD cord-006870-f5w6fw6q 2744 11 during during IN cord-006870-f5w6fw6q 2744 12 the the DT cord-006870-f5w6fw6q 2744 13 first first JJ cord-006870-f5w6fw6q 2744 14 3 3 CD cord-006870-f5w6fw6q 2744 15 days day NNS cord-006870-f5w6fw6q 2744 16 of of IN cord-006870-f5w6fw6q 2744 17 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2744 18 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2744 19 . . . cord-006870-f5w6fw6q 2745 1 After after IN cord-006870-f5w6fw6q 2745 2 3 3 CD cord-006870-f5w6fw6q 2745 3 days day NNS cord-006870-f5w6fw6q 2745 4 , , , cord-006870-f5w6fw6q 2745 5 the the DT cord-006870-f5w6fw6q 2745 6 longer long JJR cord-006870-f5w6fw6q 2745 7 patients patient NNS cord-006870-f5w6fw6q 2745 8 remained remain VBD cord-006870-f5w6fw6q 2745 9 on on IN cord-006870-f5w6fw6q 2745 10 prophylactic prophylactic JJ cord-006870-f5w6fw6q 2745 11 Cefazolin Cefazolin NNP cord-006870-f5w6fw6q 2745 12 , , , cord-006870-f5w6fw6q 2745 13 the the DT cord-006870-f5w6fw6q 2745 14 higher high JJR cord-006870-f5w6fw6q 2745 15 the the DT cord-006870-f5w6fw6q 2745 16 probability probability NN cord-006870-f5w6fw6q 2745 17 of of IN cord-006870-f5w6fw6q 2745 18 infection infection NN cord-006870-f5w6fw6q 2745 19 ( ( -LRB- cord-006870-f5w6fw6q 2745 20 Spearman Spearman NNP cord-006870-f5w6fw6q 2745 21 rank rank NN cord-006870-f5w6fw6q 2745 22 correlati correlati NN cord-006870-f5w6fw6q 2745 23 patients patient NNS cord-006870-f5w6fw6q 2745 24 who who WP cord-006870-f5w6fw6q 2745 25 received receive VBD cord-006870-f5w6fw6q 2745 26 antibiotics antibiotic NNS cord-006870-f5w6fw6q 2745 27 for for IN cord-006870-f5w6fw6q 2745 28 > > XX cord-006870-f5w6fw6q 2745 29 3 3 CD cord-006870-f5w6fw6q 2745 30 days day NNS cord-006870-f5w6fw6q 2745 31 were be VBD cord-006870-f5w6fw6q 2745 32 2.5 2.5 CD cord-006870-f5w6fw6q 2745 33 times time NNS cord-006870-f5w6fw6q 2745 34 as as RB cord-006870-f5w6fw6q 2745 35 likely likely JJ cord-006870-f5w6fw6q 2745 36 to to TO cord-006870-f5w6fw6q 2745 37 develop develop VB cord-006870-f5w6fw6q 2745 38 MDR MDR NNP cord-006870-f5w6fw6q 2745 39 infections infection NNS cord-006870-f5w6fw6q 2745 40 ( ( -LRB- cord-006870-f5w6fw6q 2745 41 95 95 CD cord-006870-f5w6fw6q 2745 42 % % NN cord-006870-f5w6fw6q 2745 43 CI,0.60 CI,0.60 NNP cord-006870-f5w6fw6q 2745 44 to to IN cord-006870-f5w6fw6q 2745 45 10.3 10.3 CD cord-006870-f5w6fw6q 2745 46 ; ; : cord-006870-f5w6fw6q 2745 47 p=0.3 p=0.3 NNP cord-006870-f5w6fw6q 2745 48 ) ) -RRB- cord-006870-f5w6fw6q 2745 49 . . . cord-006870-f5w6fw6q 2746 1 Cefazolin Cefazolin NNP cord-006870-f5w6fw6q 2746 2 may may MD cord-006870-f5w6fw6q 2746 3 prevent prevent VB cord-006870-f5w6fw6q 2746 4 infections infection NNS cord-006870-f5w6fw6q 2746 5 for for IN cord-006870-f5w6fw6q 2746 6 the the DT cord-006870-f5w6fw6q 2746 7 first first JJ cord-006870-f5w6fw6q 2746 8 3 3 CD cord-006870-f5w6fw6q 2746 9 days day NNS cord-006870-f5w6fw6q 2746 10 after after IN cord-006870-f5w6fw6q 2746 11 EVD EVD NNP cord-006870-f5w6fw6q 2746 12 insertion insertion NN cord-006870-f5w6fw6q 2746 13 . . . cord-006870-f5w6fw6q 2747 1 However however RB cord-006870-f5w6fw6q 2747 2 , , , cord-006870-f5w6fw6q 2747 3 prolonged prolonged JJ cord-006870-f5w6fw6q 2747 4 administration administration NN cord-006870-f5w6fw6q 2747 5 increased increase VBD cord-006870-f5w6fw6q 2747 6 the the DT cord-006870-f5w6fw6q 2747 7 risk risk NN cord-006870-f5w6fw6q 2747 8 of of IN cord-006870-f5w6fw6q 2747 9 MDR MDR NNP cord-006870-f5w6fw6q 2747 10 bacterial bacterial JJ cord-006870-f5w6fw6q 2747 11 infections infection NNS cord-006870-f5w6fw6q 2747 12 . . . cord-006870-f5w6fw6q 2748 1 A a DT cord-006870-f5w6fw6q 2748 2 randomized randomized JJ cord-006870-f5w6fw6q 2748 3 study study NN cord-006870-f5w6fw6q 2748 4 comparing compare VBG cord-006870-f5w6fw6q 2748 5 periprocedural periprocedural JJ cord-006870-f5w6fw6q 2748 6 ( ( -LRB- cord-006870-f5w6fw6q 2748 7 72hrs 72hrs NN cord-006870-f5w6fw6q 2748 8 ) ) -RRB- cord-006870-f5w6fw6q 2749 1 antibiotic antibiotic JJ cord-006870-f5w6fw6q 2749 2 use use NN cord-006870-f5w6fw6q 2749 3 is be VBZ cord-006870-f5w6fw6q 2749 4 needed need VBN cord-006870-f5w6fw6q 2749 5 to to TO cord-006870-f5w6fw6q 2749 6 resolve resolve VB cord-006870-f5w6fw6q 2749 7 this this DT cord-006870-f5w6fw6q 2749 8 controversy controversy NN cord-006870-f5w6fw6q 2749 9 . . . cord-006870-f5w6fw6q 2750 1 Each each DT cord-006870-f5w6fw6q 2750 2 year year NN cord-006870-f5w6fw6q 2750 3 more more JJR cord-006870-f5w6fw6q 2750 4 than than IN cord-006870-f5w6fw6q 2750 5 13,000 13,000 CD cord-006870-f5w6fw6q 2750 6 deaths death NNS cord-006870-f5w6fw6q 2750 7 are be VBP cord-006870-f5w6fw6q 2750 8 associated associate VBN cord-006870-f5w6fw6q 2750 9 with with IN cord-006870-f5w6fw6q 2750 10 urinary urinary JJ cord-006870-f5w6fw6q 2750 11 tract tract JJ cord-006870-f5w6fw6q 2750 12 infections infection NNS cord-006870-f5w6fw6q 2750 13 . . . cord-006870-f5w6fw6q 2751 1 Eighty eighty CD cord-006870-f5w6fw6q 2751 2 percent percent NN cord-006870-f5w6fw6q 2751 3 of of IN cord-006870-f5w6fw6q 2751 4 all all DT cord-006870-f5w6fw6q 2751 5 UTIs uti NNS cord-006870-f5w6fw6q 2751 6 are be VBP cord-006870-f5w6fw6q 2751 7 associated associate VBN cord-006870-f5w6fw6q 2751 8 with with IN cord-006870-f5w6fw6q 2751 9 an an DT cord-006870-f5w6fw6q 2751 10 indwelling indwell VBG cord-006870-f5w6fw6q 2751 11 catheter catheter NN cord-006870-f5w6fw6q 2751 12 . . . cord-006870-f5w6fw6q 2752 1 Neuroscience Neuroscience NNP cord-006870-f5w6fw6q 2752 2 Intensive Intensive NNP cord-006870-f5w6fw6q 2752 3 Care Care NNP cord-006870-f5w6fw6q 2752 4 ( ( -LRB- cord-006870-f5w6fw6q 2752 5 neuro neuro NNP cord-006870-f5w6fw6q 2752 6 - - HYPH cord-006870-f5w6fw6q 2752 7 ICU ICU NNP cord-006870-f5w6fw6q 2752 8 ) ) -RRB- cord-006870-f5w6fw6q 2752 9 units unit NNS cord-006870-f5w6fw6q 2752 10 have have VBP cord-006870-f5w6fw6q 2752 11 the the DT cord-006870-f5w6fw6q 2752 12 highest high JJS cord-006870-f5w6fw6q 2752 13 rates rate NNS cord-006870-f5w6fw6q 2752 14 of of IN cord-006870-f5w6fw6q 2752 15 catheter catheter NN cord-006870-f5w6fw6q 2752 16 associated associate VBD cord-006870-f5w6fw6q 2752 17 urinary urinary JJ cord-006870-f5w6fw6q 2752 18 tract tract JJ cord-006870-f5w6fw6q 2752 19 infections infection NNS cord-006870-f5w6fw6q 2752 20 . . . cord-006870-f5w6fw6q 2753 1 Catheter catheter NN cord-006870-f5w6fw6q 2753 2 associated associate VBD cord-006870-f5w6fw6q 2753 3 urinary urinary JJ cord-006870-f5w6fw6q 2753 4 tract tract NN cord-006870-f5w6fw6q 2753 5 infection infection NN cord-006870-f5w6fw6q 2753 6 ( ( -LRB- cord-006870-f5w6fw6q 2753 7 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2753 8 ) ) -RRB- cord-006870-f5w6fw6q 2753 9 increases increase VBZ cord-006870-f5w6fw6q 2753 10 morbidity morbidity NN cord-006870-f5w6fw6q 2753 11 rates rate NNS cord-006870-f5w6fw6q 2753 12 , , , cord-006870-f5w6fw6q 2753 13 length length NN cord-006870-f5w6fw6q 2753 14 of of IN cord-006870-f5w6fw6q 2753 15 stay stay NN cord-006870-f5w6fw6q 2753 16 , , , cord-006870-f5w6fw6q 2753 17 and and CC cord-006870-f5w6fw6q 2753 18 costs cost NNS cord-006870-f5w6fw6q 2753 19 among among IN cord-006870-f5w6fw6q 2753 20 hospitalized hospitalize VBN cord-006870-f5w6fw6q 2753 21 patients patient NNS cord-006870-f5w6fw6q 2753 22 . . . cord-006870-f5w6fw6q 2754 1 At at IN cord-006870-f5w6fw6q 2754 2 an an DT cord-006870-f5w6fw6q 2754 3 urban urban JJ cord-006870-f5w6fw6q 2754 4 academic academic JJ cord-006870-f5w6fw6q 2754 5 medical medical JJ cord-006870-f5w6fw6q 2754 6 center center NN cord-006870-f5w6fw6q 2754 7 , , , cord-006870-f5w6fw6q 2754 8 our -PRON- PRP$ cord-006870-f5w6fw6q 2754 9 neuro neuro NNP cord-006870-f5w6fw6q 2754 10 - - HYPH cord-006870-f5w6fw6q 2754 11 ICU ICU NNP cord-006870-f5w6fw6q 2754 12 had have VBD cord-006870-f5w6fw6q 2754 13 the the DT cord-006870-f5w6fw6q 2754 14 highest high JJS cord-006870-f5w6fw6q 2754 15 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2754 16 cases case NNS cord-006870-f5w6fw6q 2754 17 among among IN cord-006870-f5w6fw6q 2754 18 our -PRON- PRP$ cord-006870-f5w6fw6q 2754 19 ICUs icu NNS cord-006870-f5w6fw6q 2754 20 . . . cord-006870-f5w6fw6q 2755 1 The the DT cord-006870-f5w6fw6q 2755 2 purpose purpose NN cord-006870-f5w6fw6q 2755 3 of of IN cord-006870-f5w6fw6q 2755 4 this this DT cord-006870-f5w6fw6q 2755 5 project project NN cord-006870-f5w6fw6q 2755 6 was be VBD cord-006870-f5w6fw6q 2755 7 to to TO cord-006870-f5w6fw6q 2755 8 reduce reduce VB cord-006870-f5w6fw6q 2755 9 our -PRON- PRP$ cord-006870-f5w6fw6q 2755 10 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2755 11 cases case NNS cord-006870-f5w6fw6q 2755 12 by by IN cord-006870-f5w6fw6q 2755 13 50 50 CD cord-006870-f5w6fw6q 2755 14 % % NN cord-006870-f5w6fw6q 2755 15 . . . cord-006870-f5w6fw6q 2756 1 This this DT cord-006870-f5w6fw6q 2756 2 quality quality NN cord-006870-f5w6fw6q 2756 3 improvement improvement NN cord-006870-f5w6fw6q 2756 4 project project NN cord-006870-f5w6fw6q 2756 5 used use VBD cord-006870-f5w6fw6q 2756 6 several several JJ cord-006870-f5w6fw6q 2756 7 strategies strategy NNS cord-006870-f5w6fw6q 2756 8 : : : cord-006870-f5w6fw6q 2756 9 ( ( -LRB- cord-006870-f5w6fw6q 2756 10 1 1 LS cord-006870-f5w6fw6q 2756 11 ) ) -RRB- cord-006870-f5w6fw6q 2756 12 formed form VBD cord-006870-f5w6fw6q 2756 13 a a DT cord-006870-f5w6fw6q 2756 14 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 2756 15 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2756 16 Task Task NNP cord-006870-f5w6fw6q 2756 17 Force Force NNP cord-006870-f5w6fw6q 2756 18 that that WDT cord-006870-f5w6fw6q 2756 19 included include VBD cord-006870-f5w6fw6q 2756 20 nurses nurse NNS cord-006870-f5w6fw6q 2756 21 , , , cord-006870-f5w6fw6q 2756 22 physicians physician NNS cord-006870-f5w6fw6q 2756 23 , , , cord-006870-f5w6fw6q 2756 24 infection infection NN cord-006870-f5w6fw6q 2756 25 control control NN cord-006870-f5w6fw6q 2756 26 , , , cord-006870-f5w6fw6q 2756 27 management management NN cord-006870-f5w6fw6q 2756 28 and and CC cord-006870-f5w6fw6q 2756 29 supply supply NN cord-006870-f5w6fw6q 2756 30 chain chain NN cord-006870-f5w6fw6q 2756 31 personnel personnel NNS cord-006870-f5w6fw6q 2756 32 ; ; , cord-006870-f5w6fw6q 2756 33 ( ( -LRB- cord-006870-f5w6fw6q 2756 34 2 2 LS cord-006870-f5w6fw6q 2756 35 ) ) -RRB- cord-006870-f5w6fw6q 2756 36 developed develop VBD cord-006870-f5w6fw6q 2756 37 an an DT cord-006870-f5w6fw6q 2756 38 action action NN cord-006870-f5w6fw6q 2756 39 plan plan NN cord-006870-f5w6fw6q 2756 40 to to TO cord-006870-f5w6fw6q 2756 41 update update VB cord-006870-f5w6fw6q 2756 42 standard standard NN cord-006870-f5w6fw6q 2756 43 of of IN cord-006870-f5w6fw6q 2756 44 practice practice NN cord-006870-f5w6fw6q 2756 45 by by IN cord-006870-f5w6fw6q 2756 46 conducting conduct VBG cord-006870-f5w6fw6q 2756 47 a a DT cord-006870-f5w6fw6q 2756 48 review review NN cord-006870-f5w6fw6q 2756 49 of of IN cord-006870-f5w6fw6q 2756 50 the the DT cord-006870-f5w6fw6q 2756 51 literature literature NN cord-006870-f5w6fw6q 2756 52 and and CC cord-006870-f5w6fw6q 2756 53 pilot pilot NN cord-006870-f5w6fw6q 2756 54 testing test VBG cord-006870-f5w6fw6q 2756 55 new new JJ cord-006870-f5w6fw6q 2756 56 products product NNS cord-006870-f5w6fw6q 2756 57 ; ; , cord-006870-f5w6fw6q 2756 58 and and CC cord-006870-f5w6fw6q 2756 59 , , , cord-006870-f5w6fw6q 2756 60 ( ( -LRB- cord-006870-f5w6fw6q 2756 61 3 3 LS cord-006870-f5w6fw6q 2756 62 ) ) -RRB- cord-006870-f5w6fw6q 2756 63 educated educate VBN cord-006870-f5w6fw6q 2756 64 staff staff NN cord-006870-f5w6fw6q 2756 65 using use VBG cord-006870-f5w6fw6q 2756 66 huddles huddle NNS cord-006870-f5w6fw6q 2756 67 , , , cord-006870-f5w6fw6q 2756 68 a a DT cord-006870-f5w6fw6q 2756 69 bedside bedside NN cord-006870-f5w6fw6q 2756 70 guide guide NN cord-006870-f5w6fw6q 2756 71 , , , cord-006870-f5w6fw6q 2756 72 and and CC cord-006870-f5w6fw6q 2756 73 email email NN cord-006870-f5w6fw6q 2756 74 blasts blast NNS cord-006870-f5w6fw6q 2756 75 with with IN cord-006870-f5w6fw6q 2756 76 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2756 77 facts fact NNS cord-006870-f5w6fw6q 2756 78 starting start VBG cord-006870-f5w6fw6q 2756 79 in in IN cord-006870-f5w6fw6q 2756 80 August August NNP cord-006870-f5w6fw6q 2756 81 2016 2016 CD cord-006870-f5w6fw6q 2756 82 . . . cord-006870-f5w6fw6q 2757 1 Additionally additionally RB cord-006870-f5w6fw6q 2757 2 , , , cord-006870-f5w6fw6q 2757 3 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2757 4 prevention prevention NN cord-006870-f5w6fw6q 2757 5 was be VBD cord-006870-f5w6fw6q 2757 6 discussed discuss VBN cord-006870-f5w6fw6q 2757 7 during during IN cord-006870-f5w6fw6q 2757 8 patient patient JJ cord-006870-f5w6fw6q 2757 9 handoffs handoff NNS cord-006870-f5w6fw6q 2757 10 among among IN cord-006870-f5w6fw6q 2757 11 nurses nurse NNS cord-006870-f5w6fw6q 2757 12 and and CC cord-006870-f5w6fw6q 2757 13 physicians physician NNS cord-006870-f5w6fw6q 2757 14 . . . cord-006870-f5w6fw6q 2758 1 Data datum NNS cord-006870-f5w6fw6q 2758 2 were be VBD cord-006870-f5w6fw6q 2758 3 collected collect VBN cord-006870-f5w6fw6q 2758 4 for for IN cord-006870-f5w6fw6q 2758 5 all all DT cord-006870-f5w6fw6q 2758 6 neuro neuro NNP cord-006870-f5w6fw6q 2758 7 - - HYPH cord-006870-f5w6fw6q 2758 8 ICU ICU NNP cord-006870-f5w6fw6q 2758 9 patients patient NNS cord-006870-f5w6fw6q 2758 10 from from IN cord-006870-f5w6fw6q 2758 11 fiscal fiscal JJ cord-006870-f5w6fw6q 2758 12 year year NN cord-006870-f5w6fw6q 2758 13 ( ( -LRB- cord-006870-f5w6fw6q 2758 14 FY FY NNP cord-006870-f5w6fw6q 2758 15 ) ) -RRB- cord-006870-f5w6fw6q 2758 16 2016 2016 CD cord-006870-f5w6fw6q 2758 17 - - SYM cord-006870-f5w6fw6q 2758 18 2017 2017 CD cord-006870-f5w6fw6q 2758 19 . . . cord-006870-f5w6fw6q 2759 1 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2759 2 cases case NNS cord-006870-f5w6fw6q 2759 3 are be VBP cord-006870-f5w6fw6q 2759 4 determined determine VBN cord-006870-f5w6fw6q 2759 5 by by IN cord-006870-f5w6fw6q 2759 6 utilizing utilize VBG cord-006870-f5w6fw6q 2759 7 CDC CDC NNP cord-006870-f5w6fw6q 2759 8 's 's POS cord-006870-f5w6fw6q 2759 9 National National NNP cord-006870-f5w6fw6q 2759 10 Healthcare Healthcare NNP cord-006870-f5w6fw6q 2759 11 Safety Safety NNP cord-006870-f5w6fw6q 2759 12 Network Network NNP cord-006870-f5w6fw6q 2759 13 . . . cord-006870-f5w6fw6q 2760 1 Analysis analysis NN cord-006870-f5w6fw6q 2760 2 included include VBD cord-006870-f5w6fw6q 2760 3 evaluation evaluation NN cord-006870-f5w6fw6q 2760 4 of of IN cord-006870-f5w6fw6q 2760 5 trends trend NNS cord-006870-f5w6fw6q 2760 6 across across IN cord-006870-f5w6fw6q 2760 7 time time NN cord-006870-f5w6fw6q 2760 8 . . . cord-006870-f5w6fw6q 2761 1 We -PRON- PRP cord-006870-f5w6fw6q 2761 2 reduced reduce VBD cord-006870-f5w6fw6q 2761 3 our -PRON- PRP$ cord-006870-f5w6fw6q 2761 4 number number NN cord-006870-f5w6fw6q 2761 5 of of IN cord-006870-f5w6fw6q 2761 6 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2761 7 cases case NNS cord-006870-f5w6fw6q 2761 8 from from IN cord-006870-f5w6fw6q 2761 9 5 5 CD cord-006870-f5w6fw6q 2761 10 in in IN cord-006870-f5w6fw6q 2761 11 FY FY NNP cord-006870-f5w6fw6q 2761 12 2016 2016 CD cord-006870-f5w6fw6q 2761 13 to to IN cord-006870-f5w6fw6q 2761 14 1 1 CD cord-006870-f5w6fw6q 2761 15 in in IN cord-006870-f5w6fw6q 2761 16 FY FY NNP cord-006870-f5w6fw6q 2761 17 2017 2017 CD cord-006870-f5w6fw6q 2761 18 . . . cord-006870-f5w6fw6q 2762 1 As as IN cord-006870-f5w6fw6q 2762 2 of of IN cord-006870-f5w6fw6q 2762 3 the the DT cord-006870-f5w6fw6q 2762 4 beginning beginning NN cord-006870-f5w6fw6q 2762 5 of of IN cord-006870-f5w6fw6q 2762 6 FY FY NNP cord-006870-f5w6fw6q 2762 7 2018 2018 CD cord-006870-f5w6fw6q 2762 8 , , , cord-006870-f5w6fw6q 2762 9 we -PRON- PRP cord-006870-f5w6fw6q 2762 10 have have VBP cord-006870-f5w6fw6q 2762 11 not not RB cord-006870-f5w6fw6q 2762 12 had have VBN cord-006870-f5w6fw6q 2762 13 a a DT cord-006870-f5w6fw6q 2762 14 CAUTI cauti NN cord-006870-f5w6fw6q 2762 15 for for IN cord-006870-f5w6fw6q 2762 16 365 365 CD cord-006870-f5w6fw6q 2762 17 days day NNS cord-006870-f5w6fw6q 2762 18 . . . cord-006870-f5w6fw6q 2763 1 A a DT cord-006870-f5w6fw6q 2763 2 comprehensive comprehensive JJ cord-006870-f5w6fw6q 2763 3 approach approach NN cord-006870-f5w6fw6q 2763 4 with with IN cord-006870-f5w6fw6q 2763 5 a a DT cord-006870-f5w6fw6q 2763 6 strong strong JJ cord-006870-f5w6fw6q 2763 7 commitment commitment NN cord-006870-f5w6fw6q 2763 8 by by IN cord-006870-f5w6fw6q 2763 9 clinicians clinician NNS cord-006870-f5w6fw6q 2763 10 is be VBZ cord-006870-f5w6fw6q 2763 11 critical critical JJ cord-006870-f5w6fw6q 2763 12 for for IN cord-006870-f5w6fw6q 2763 13 sustaining sustain VBG cord-006870-f5w6fw6q 2763 14 a a DT cord-006870-f5w6fw6q 2763 15 reduction reduction NN cord-006870-f5w6fw6q 2763 16 in in IN cord-006870-f5w6fw6q 2763 17 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2763 18 . . . cord-006870-f5w6fw6q 2764 1 We -PRON- PRP cord-006870-f5w6fw6q 2764 2 reduced reduce VBD cord-006870-f5w6fw6q 2764 3 our -PRON- PRP$ cord-006870-f5w6fw6q 2764 4 cases case NNS cord-006870-f5w6fw6q 2764 5 and and CC cord-006870-f5w6fw6q 2764 6 exceeded exceed VBD cord-006870-f5w6fw6q 2764 7 our -PRON- PRP$ cord-006870-f5w6fw6q 2764 8 goal goal NN cord-006870-f5w6fw6q 2764 9 . . . cord-006870-f5w6fw6q 2765 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2765 2 efforts effort NNS cord-006870-f5w6fw6q 2765 3 to to TO cord-006870-f5w6fw6q 2765 4 provide provide VB cord-006870-f5w6fw6q 2765 5 evidence evidence NN cord-006870-f5w6fw6q 2765 6 - - HYPH cord-006870-f5w6fw6q 2765 7 based base VBN cord-006870-f5w6fw6q 2765 8 care care NN cord-006870-f5w6fw6q 2765 9 are be VBP cord-006870-f5w6fw6q 2765 10 ongoing ongoing JJ cord-006870-f5w6fw6q 2765 11 as as IN cord-006870-f5w6fw6q 2765 12 we -PRON- PRP cord-006870-f5w6fw6q 2765 13 continue continue VBP cord-006870-f5w6fw6q 2765 14 to to TO cord-006870-f5w6fw6q 2765 15 monitor monitor VB cord-006870-f5w6fw6q 2765 16 the the DT cord-006870-f5w6fw6q 2765 17 research research NN cord-006870-f5w6fw6q 2765 18 and and CC cord-006870-f5w6fw6q 2765 19 upcoming upcoming JJ cord-006870-f5w6fw6q 2765 20 supplies supply NNS cord-006870-f5w6fw6q 2765 21 aimed aim VBN cord-006870-f5w6fw6q 2765 22 at at IN cord-006870-f5w6fw6q 2765 23 making make VBG cord-006870-f5w6fw6q 2765 24 hospitalacquired hospitalacquire VBN cord-006870-f5w6fw6q 2765 25 CAUTI CAUTI NNP cord-006870-f5w6fw6q 2765 26 a a DT cord-006870-f5w6fw6q 2765 27 never never RB cord-006870-f5w6fw6q 2765 28 event event NN cord-006870-f5w6fw6q 2765 29 . . . cord-006870-f5w6fw6q 2766 1 Isophane Isophane NNP cord-006870-f5w6fw6q 2766 2 insulin insulin NN cord-006870-f5w6fw6q 2766 3 ( ( -LRB- cord-006870-f5w6fw6q 2766 4 NPH NPH NNP cord-006870-f5w6fw6q 2766 5 ) ) -RRB- cord-006870-f5w6fw6q 2766 6 is be VBZ cord-006870-f5w6fw6q 2766 7 a a DT cord-006870-f5w6fw6q 2766 8 commonly commonly RB cord-006870-f5w6fw6q 2766 9 prescribed prescribe VBN cord-006870-f5w6fw6q 2766 10 basal basal NN cord-006870-f5w6fw6q 2766 11 insulin insulin NN cord-006870-f5w6fw6q 2766 12 to to TO cord-006870-f5w6fw6q 2766 13 manage manage VB cord-006870-f5w6fw6q 2766 14 hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 2766 15 in in IN cord-006870-f5w6fw6q 2766 16 critically critically RB cord-006870-f5w6fw6q 2766 17 ill ill JJ cord-006870-f5w6fw6q 2766 18 patients patient NNS cord-006870-f5w6fw6q 2766 19 on on IN cord-006870-f5w6fw6q 2766 20 continuous continuous JJ cord-006870-f5w6fw6q 2766 21 tube tube NN cord-006870-f5w6fw6q 2766 22 feeding feeding NN cord-006870-f5w6fw6q 2766 23 due due IN cord-006870-f5w6fw6q 2766 24 to to IN cord-006870-f5w6fw6q 2766 25 its -PRON- PRP$ cord-006870-f5w6fw6q 2766 26 intermediate intermediate JJ cord-006870-f5w6fw6q 2766 27 duration duration NN cord-006870-f5w6fw6q 2766 28 of of IN cord-006870-f5w6fw6q 2766 29 action action NN cord-006870-f5w6fw6q 2766 30 . . . cord-006870-f5w6fw6q 2767 1 However however RB cord-006870-f5w6fw6q 2767 2 , , , cord-006870-f5w6fw6q 2767 3 the the DT cord-006870-f5w6fw6q 2767 4 incidence incidence NN cord-006870-f5w6fw6q 2767 5 of of IN cord-006870-f5w6fw6q 2767 6 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 2767 7 may may MD cord-006870-f5w6fw6q 2767 8 be be VB cord-006870-f5w6fw6q 2767 9 higher high JJR cord-006870-f5w6fw6q 2767 10 given give VBN cord-006870-f5w6fw6q 2767 11 the the DT cord-006870-f5w6fw6q 2767 12 duration duration NN cord-006870-f5w6fw6q 2767 13 of of IN cord-006870-f5w6fw6q 2767 14 NPH NPH NNP cord-006870-f5w6fw6q 2767 15 can can MD cord-006870-f5w6fw6q 2767 16 last last VB cord-006870-f5w6fw6q 2767 17 between between IN cord-006870-f5w6fw6q 2767 18 14 14 CD cord-006870-f5w6fw6q 2767 19 - - SYM cord-006870-f5w6fw6q 2767 20 24 24 CD cord-006870-f5w6fw6q 2767 21 hours hour NNS cord-006870-f5w6fw6q 2767 22 and and CC cord-006870-f5w6fw6q 2767 23 because because IN cord-006870-f5w6fw6q 2767 24 of of IN cord-006870-f5w6fw6q 2767 25 the the DT cord-006870-f5w6fw6q 2767 26 potential potential NN cord-006870-f5w6fw6q 2767 27 for for IN cord-006870-f5w6fw6q 2767 28 unexpected unexpected JJ cord-006870-f5w6fw6q 2767 29 interruption interruption NN cord-006870-f5w6fw6q 2767 30 in in IN cord-006870-f5w6fw6q 2767 31 feeding feeding NN cord-006870-f5w6fw6q 2767 32 . . . cord-006870-f5w6fw6q 2768 1 Using use VBG cord-006870-f5w6fw6q 2768 2 scheduled schedule VBN cord-006870-f5w6fw6q 2768 3 regular regular JJ cord-006870-f5w6fw6q 2768 4 insulin insulin NN cord-006870-f5w6fw6q 2768 5 ( ( -LRB- cord-006870-f5w6fw6q 2768 6 RI RI NNP cord-006870-f5w6fw6q 2768 7 ) ) -RRB- cord-006870-f5w6fw6q 2768 8 instead instead RB cord-006870-f5w6fw6q 2768 9 of of IN cord-006870-f5w6fw6q 2768 10 NPH NPH NNP cord-006870-f5w6fw6q 2768 11 may may MD cord-006870-f5w6fw6q 2768 12 reduce reduce VB cord-006870-f5w6fw6q 2768 13 this this DT cord-006870-f5w6fw6q 2768 14 risk risk NN cord-006870-f5w6fw6q 2768 15 given give VBD cord-006870-f5w6fw6q 2768 16 its -PRON- PRP$ cord-006870-f5w6fw6q 2768 17 shorter short JJR cord-006870-f5w6fw6q 2768 18 duration duration NN cord-006870-f5w6fw6q 2768 19 of of IN cord-006870-f5w6fw6q 2768 20 action action NN cord-006870-f5w6fw6q 2768 21 . . . cord-006870-f5w6fw6q 2769 1 It -PRON- PRP cord-006870-f5w6fw6q 2769 2 may may MD cord-006870-f5w6fw6q 2769 3 also also RB cord-006870-f5w6fw6q 2769 4 improve improve VB cord-006870-f5w6fw6q 2769 5 glycemic glycemic NN cord-006870-f5w6fw6q 2769 6 control control NN cord-006870-f5w6fw6q 2769 7 due due JJ cord-006870-f5w6fw6q 2769 8 to to IN cord-006870-f5w6fw6q 2769 9 more more RBR cord-006870-f5w6fw6q 2769 10 frequent frequent JJ cord-006870-f5w6fw6q 2769 11 titration titration NN cord-006870-f5w6fw6q 2769 12 . . . cord-006870-f5w6fw6q 2770 1 This this DT cord-006870-f5w6fw6q 2770 2 was be VBD cord-006870-f5w6fw6q 2770 3 a a DT cord-006870-f5w6fw6q 2770 4 single single JJ cord-006870-f5w6fw6q 2770 5 - - HYPH cord-006870-f5w6fw6q 2770 6 center center NN cord-006870-f5w6fw6q 2770 7 , , , cord-006870-f5w6fw6q 2770 8 retrospective retrospective JJ cord-006870-f5w6fw6q 2770 9 , , , cord-006870-f5w6fw6q 2770 10 observational observational JJ cord-006870-f5w6fw6q 2770 11 , , , cord-006870-f5w6fw6q 2770 12 cohort cohort NN cord-006870-f5w6fw6q 2770 13 study study NN cord-006870-f5w6fw6q 2770 14 from from IN cord-006870-f5w6fw6q 2770 15 December December NNP cord-006870-f5w6fw6q 2770 16 2016 2016 CD cord-006870-f5w6fw6q 2770 17 to to IN cord-006870-f5w6fw6q 2770 18 May May NNP cord-006870-f5w6fw6q 2770 19 2017 2017 CD cord-006870-f5w6fw6q 2770 20 . . . cord-006870-f5w6fw6q 2771 1 Patients patient NNS cord-006870-f5w6fw6q 2771 2 on on IN cord-006870-f5w6fw6q 2771 3 continuous continuous JJ cord-006870-f5w6fw6q 2771 4 tube tube NN cord-006870-f5w6fw6q 2771 5 feeding feeding NN cord-006870-f5w6fw6q 2771 6 who who WP cord-006870-f5w6fw6q 2771 7 were be VBD cord-006870-f5w6fw6q 2771 8 prescribed prescribe VBN cord-006870-f5w6fw6q 2771 9 scheduled schedule VBN cord-006870-f5w6fw6q 2771 10 RI RI NNP cord-006870-f5w6fw6q 2771 11 were be VBD cord-006870-f5w6fw6q 2771 12 compared compare VBN cord-006870-f5w6fw6q 2771 13 to to IN cord-006870-f5w6fw6q 2771 14 those those DT cord-006870-f5w6fw6q 2771 15 prescribed prescribe VBN cord-006870-f5w6fw6q 2771 16 NPH NPH NNP cord-006870-f5w6fw6q 2771 17 . . . cord-006870-f5w6fw6q 2772 1 All all DT cord-006870-f5w6fw6q 2772 2 patients patient NNS cord-006870-f5w6fw6q 2772 3 continued continue VBD cord-006870-f5w6fw6q 2772 4 to to TO cord-006870-f5w6fw6q 2772 5 receive receive VB cord-006870-f5w6fw6q 2772 6 an an DT cord-006870-f5w6fw6q 2772 7 insulin insulin NN cord-006870-f5w6fw6q 2772 8 sliding slide VBG cord-006870-f5w6fw6q 2772 9 scale scale NN cord-006870-f5w6fw6q 2772 10 . . . cord-006870-f5w6fw6q 2773 1 Choice choice NN cord-006870-f5w6fw6q 2773 2 of of IN cord-006870-f5w6fw6q 2773 3 agent agent NN cord-006870-f5w6fw6q 2773 4 was be VBD cord-006870-f5w6fw6q 2773 5 determined determine VBN cord-006870-f5w6fw6q 2773 6 by by IN cord-006870-f5w6fw6q 2773 7 the the DT cord-006870-f5w6fw6q 2773 8 bedside bedside NN cord-006870-f5w6fw6q 2773 9 team team NN cord-006870-f5w6fw6q 2773 10 . . . cord-006870-f5w6fw6q 2774 1 The the DT cord-006870-f5w6fw6q 2774 2 primary primary JJ cord-006870-f5w6fw6q 2774 3 endpoint endpoint NN cord-006870-f5w6fw6q 2774 4 was be VBD cord-006870-f5w6fw6q 2774 5 incidence incidence NN cord-006870-f5w6fw6q 2774 6 of of IN cord-006870-f5w6fw6q 2774 7 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 2774 8 while while IN cord-006870-f5w6fw6q 2774 9 secondary secondary JJ cord-006870-f5w6fw6q 2774 10 endpoint endpoint NN cord-006870-f5w6fw6q 2774 11 assessed assess VBN cord-006870-f5w6fw6q 2774 12 efficacy efficacy NN cord-006870-f5w6fw6q 2774 13 . . . cord-006870-f5w6fw6q 2774 14 _SP cord-006870-f5w6fw6q 2775 1 In in IN cord-006870-f5w6fw6q 2775 2 our -PRON- PRP$ cord-006870-f5w6fw6q 2775 3 patient patient JJ cord-006870-f5w6fw6q 2775 4 population population NN cord-006870-f5w6fw6q 2775 5 , , , cord-006870-f5w6fw6q 2775 6 a a DT cord-006870-f5w6fw6q 2775 7 higher high JJR cord-006870-f5w6fw6q 2775 8 incidence incidence NN cord-006870-f5w6fw6q 2775 9 of of IN cord-006870-f5w6fw6q 2775 10 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 2775 11 was be VBD cord-006870-f5w6fw6q 2775 12 seen see VBN cord-006870-f5w6fw6q 2775 13 in in IN cord-006870-f5w6fw6q 2775 14 those those DT cord-006870-f5w6fw6q 2775 15 that that WDT cord-006870-f5w6fw6q 2775 16 received receive VBD cord-006870-f5w6fw6q 2775 17 NPH NPH NNP cord-006870-f5w6fw6q 2775 18 . . . cord-006870-f5w6fw6q 2776 1 Hypertonic Hypertonic NNP cord-006870-f5w6fw6q 2776 2 saline saline NN cord-006870-f5w6fw6q 2776 3 bolus bolus NN cord-006870-f5w6fw6q 2776 4 ( ( -LRB- cord-006870-f5w6fw6q 2776 5 HSB HSB NNP cord-006870-f5w6fw6q 2776 6 ) ) -RRB- cord-006870-f5w6fw6q 2776 7 is be VBZ cord-006870-f5w6fw6q 2776 8 a a DT cord-006870-f5w6fw6q 2776 9 proven prove VBN cord-006870-f5w6fw6q 2776 10 intervention intervention NN cord-006870-f5w6fw6q 2776 11 for for IN cord-006870-f5w6fw6q 2776 12 neurological neurological JJ cord-006870-f5w6fw6q 2776 13 emergencies emergency NNS cord-006870-f5w6fw6q 2776 14 arising arise VBG cord-006870-f5w6fw6q 2776 15 from from IN cord-006870-f5w6fw6q 2776 16 cerebral cerebral JJ cord-006870-f5w6fw6q 2776 17 edema edema NN cord-006870-f5w6fw6q 2776 18 and and CC cord-006870-f5w6fw6q 2776 19 increased increase VBN cord-006870-f5w6fw6q 2776 20 intracranial intracranial JJ cord-006870-f5w6fw6q 2776 21 pressure pressure NN cord-006870-f5w6fw6q 2776 22 . . . cord-006870-f5w6fw6q 2777 1 Safety safety NN cord-006870-f5w6fw6q 2777 2 of of IN cord-006870-f5w6fw6q 2777 3 HSB HSB NNP cord-006870-f5w6fw6q 2777 4 administered administer VBD cord-006870-f5w6fw6q 2777 5 via via IN cord-006870-f5w6fw6q 2777 6 central central JJ cord-006870-f5w6fw6q 2777 7 venous venous JJ cord-006870-f5w6fw6q 2777 8 catheters catheter NNS cord-006870-f5w6fw6q 2777 9 is be VBZ cord-006870-f5w6fw6q 2777 10 well well RB cord-006870-f5w6fw6q 2777 11 established establish VBN cord-006870-f5w6fw6q 2777 12 . . . cord-006870-f5w6fw6q 2778 1 However however RB cord-006870-f5w6fw6q 2778 2 , , , cord-006870-f5w6fw6q 2778 3 infusion infusion NN cord-006870-f5w6fw6q 2778 4 of of IN cord-006870-f5w6fw6q 2778 5 HSB HSB NNP cord-006870-f5w6fw6q 2778 6 through through IN cord-006870-f5w6fw6q 2778 7 peripheral peripheral JJ cord-006870-f5w6fw6q 2778 8 intravenous intravenous JJ cord-006870-f5w6fw6q 2778 9 access access NN cord-006870-f5w6fw6q 2778 10 raises raise VBZ cord-006870-f5w6fw6q 2778 11 concern concern NN cord-006870-f5w6fw6q 2778 12 for for IN cord-006870-f5w6fw6q 2778 13 complications complication NNS cord-006870-f5w6fw6q 2778 14 related relate VBN cord-006870-f5w6fw6q 2778 15 to to IN cord-006870-f5w6fw6q 2778 16 caustic caustic JJ cord-006870-f5w6fw6q 2778 17 nature nature NN cord-006870-f5w6fw6q 2778 18 of of IN cord-006870-f5w6fw6q 2778 19 the the DT cord-006870-f5w6fw6q 2778 20 solution solution NN cord-006870-f5w6fw6q 2778 21 . . . cord-006870-f5w6fw6q 2779 1 We -PRON- PRP cord-006870-f5w6fw6q 2779 2 aim aim VBP cord-006870-f5w6fw6q 2779 3 to to TO cord-006870-f5w6fw6q 2779 4 assess assess VB cord-006870-f5w6fw6q 2779 5 the the DT cord-006870-f5w6fw6q 2779 6 safety safety NN cord-006870-f5w6fw6q 2779 7 of of IN cord-006870-f5w6fw6q 2779 8 peripherally peripherally RB cord-006870-f5w6fw6q 2779 9 administered administer VBN cord-006870-f5w6fw6q 2779 10 boluses bolus NNS cord-006870-f5w6fw6q 2779 11 of of IN cord-006870-f5w6fw6q 2779 12 hypertonic hypertonic JJ cord-006870-f5w6fw6q 2779 13 saline saline NN cord-006870-f5w6fw6q 2779 14 ( ( -LRB- cord-006870-f5w6fw6q 2779 15 3 3 CD cord-006870-f5w6fw6q 2779 16 % % NN cord-006870-f5w6fw6q 2779 17 sodium sodium NN cord-006870-f5w6fw6q 2779 18 chloride chloride NN cord-006870-f5w6fw6q 2779 19 ) ) -RRB- cord-006870-f5w6fw6q 2779 20 at at IN cord-006870-f5w6fw6q 2779 21 a a DT cord-006870-f5w6fw6q 2779 22 regional regional JJ cord-006870-f5w6fw6q 2779 23 Level Level NNP cord-006870-f5w6fw6q 2779 24 1 1 CD cord-006870-f5w6fw6q 2779 25 Trauma Trauma NNP cord-006870-f5w6fw6q 2779 26 and and CC cord-006870-f5w6fw6q 2779 27 Comprehensive Comprehensive NNP cord-006870-f5w6fw6q 2779 28 Stroke Stroke NNP cord-006870-f5w6fw6q 2779 29 Center Center NNP cord-006870-f5w6fw6q 2779 30 . . . cord-006870-f5w6fw6q 2780 1 We -PRON- PRP cord-006870-f5w6fw6q 2780 2 performed perform VBD cord-006870-f5w6fw6q 2780 3 retrospective retrospective JJ cord-006870-f5w6fw6q 2780 4 chart chart NN cord-006870-f5w6fw6q 2780 5 review review NN cord-006870-f5w6fw6q 2780 6 of of IN cord-006870-f5w6fw6q 2780 7 patients patient NNS cord-006870-f5w6fw6q 2780 8 who who WP cord-006870-f5w6fw6q 2780 9 received receive VBD cord-006870-f5w6fw6q 2780 10 HSBs hsb NNS cord-006870-f5w6fw6q 2780 11 from from IN cord-006870-f5w6fw6q 2780 12 January January NNP cord-006870-f5w6fw6q 2780 13 1 1 CD cord-006870-f5w6fw6q 2780 14 , , , cord-006870-f5w6fw6q 2780 15 2014 2014 CD cord-006870-f5w6fw6q 2780 16 to to IN cord-006870-f5w6fw6q 2780 17 January January NNP cord-006870-f5w6fw6q 2780 18 1 1 CD cord-006870-f5w6fw6q 2780 19 , , , cord-006870-f5w6fw6q 2780 20 2015 2015 CD cord-006870-f5w6fw6q 2780 21 as as IN cord-006870-f5w6fw6q 2780 22 part part NN cord-006870-f5w6fw6q 2780 23 of of IN cord-006870-f5w6fw6q 2780 24 a a DT cord-006870-f5w6fw6q 2780 25 quality quality NN cord-006870-f5w6fw6q 2780 26 improvement improvement NN cord-006870-f5w6fw6q 2780 27 project project NN cord-006870-f5w6fw6q 2780 28 . . . cord-006870-f5w6fw6q 2781 1 We -PRON- PRP cord-006870-f5w6fw6q 2781 2 identified identify VBD cord-006870-f5w6fw6q 2781 3 167 167 CD cord-006870-f5w6fw6q 2781 4 instances instance NNS cord-006870-f5w6fw6q 2781 5 of of IN cord-006870-f5w6fw6q 2781 6 HSB HSB NNP cord-006870-f5w6fw6q 2781 7 administration administration NN cord-006870-f5w6fw6q 2781 8 . . . cord-006870-f5w6fw6q 2782 1 The the DT cord-006870-f5w6fw6q 2782 2 cases case NNS cord-006870-f5w6fw6q 2782 3 were be VBD cord-006870-f5w6fw6q 2782 4 individually individually RB cord-006870-f5w6fw6q 2782 5 reviewed review VBN cord-006870-f5w6fw6q 2782 6 for for IN cord-006870-f5w6fw6q 2782 7 IV IV NNP cord-006870-f5w6fw6q 2782 8 gauge gauge NN cord-006870-f5w6fw6q 2782 9 , , , cord-006870-f5w6fw6q 2782 10 location location NN cord-006870-f5w6fw6q 2782 11 of of IN cord-006870-f5w6fw6q 2782 12 the the DT cord-006870-f5w6fw6q 2782 13 IV IV NNP cord-006870-f5w6fw6q 2782 14 , , , cord-006870-f5w6fw6q 2782 15 whether whether IN cord-006870-f5w6fw6q 2782 16 central central JJ cord-006870-f5w6fw6q 2782 17 access access NN cord-006870-f5w6fw6q 2782 18 was be VBD cord-006870-f5w6fw6q 2782 19 present present JJ cord-006870-f5w6fw6q 2782 20 at at IN cord-006870-f5w6fw6q 2782 21 the the DT cord-006870-f5w6fw6q 2782 22 time time NN cord-006870-f5w6fw6q 2782 23 of of IN cord-006870-f5w6fw6q 2782 24 administration administration NN cord-006870-f5w6fw6q 2782 25 , , , cord-006870-f5w6fw6q 2782 26 documentation documentation NN cord-006870-f5w6fw6q 2782 27 of of IN cord-006870-f5w6fw6q 2782 28 IV IV NNP cord-006870-f5w6fw6q 2782 29 removal removal NN cord-006870-f5w6fw6q 2782 30 , , , cord-006870-f5w6fw6q 2782 31 and and CC cord-006870-f5w6fw6q 2782 32 volume volume NN cord-006870-f5w6fw6q 2782 33 of of IN cord-006870-f5w6fw6q 2782 34 boluses bolus NNS cord-006870-f5w6fw6q 2782 35 . . . cord-006870-f5w6fw6q 2783 1 Patients patient NNS cord-006870-f5w6fw6q 2783 2 were be VBD cord-006870-f5w6fw6q 2783 3 excluded exclude VBN cord-006870-f5w6fw6q 2783 4 if if IN cord-006870-f5w6fw6q 2783 5 there there EX cord-006870-f5w6fw6q 2783 6 was be VBD cord-006870-f5w6fw6q 2783 7 concurrent concurrent JJ cord-006870-f5w6fw6q 2783 8 central central JJ cord-006870-f5w6fw6q 2783 9 venous venous JJ cord-006870-f5w6fw6q 2783 10 access access NN cord-006870-f5w6fw6q 2783 11 catheter catheter NN cord-006870-f5w6fw6q 2783 12 present present JJ cord-006870-f5w6fw6q 2783 13 at at IN cord-006870-f5w6fw6q 2783 14 the the DT cord-006870-f5w6fw6q 2783 15 time time NN cord-006870-f5w6fw6q 2783 16 of of IN cord-006870-f5w6fw6q 2783 17 HSB HSB NNP cord-006870-f5w6fw6q 2783 18 administration administration NN cord-006870-f5w6fw6q 2783 19 or or CC cord-006870-f5w6fw6q 2783 20 unrelated unrelated JJ cord-006870-f5w6fw6q 2783 21 death death NN cord-006870-f5w6fw6q 2783 22 within within IN cord-006870-f5w6fw6q 2783 23 12 12 CD cord-006870-f5w6fw6q 2783 24 hours hour NNS cord-006870-f5w6fw6q 2783 25 after after IN cord-006870-f5w6fw6q 2783 26 administration administration NN cord-006870-f5w6fw6q 2783 27 of of IN cord-006870-f5w6fw6q 2783 28 HSB HSB NNP cord-006870-f5w6fw6q 2783 29 . . . cord-006870-f5w6fw6q 2784 1 Adverse adverse JJ cord-006870-f5w6fw6q 2784 2 events event NNS cord-006870-f5w6fw6q 2784 3 were be VBD cord-006870-f5w6fw6q 2784 4 defined define VBN cord-006870-f5w6fw6q 2784 5 as as IN cord-006870-f5w6fw6q 2784 6 line line NN cord-006870-f5w6fw6q 2784 7 infiltration infiltration NN cord-006870-f5w6fw6q 2784 8 , , , cord-006870-f5w6fw6q 2784 9 erythema erythema NN cord-006870-f5w6fw6q 2784 10 , , , cord-006870-f5w6fw6q 2784 11 or or CC cord-006870-f5w6fw6q 2784 12 swelling swell VBG cord-006870-f5w6fw6q 2784 13 at at IN cord-006870-f5w6fw6q 2784 14 the the DT cord-006870-f5w6fw6q 2784 15 site site NN cord-006870-f5w6fw6q 2784 16 of of IN cord-006870-f5w6fw6q 2784 17 HSB HSB NNP cord-006870-f5w6fw6q 2784 18 administration administration NN cord-006870-f5w6fw6q 2784 19 . . . cord-006870-f5w6fw6q 2785 1 111 111 CD cord-006870-f5w6fw6q 2785 2 charts chart NNS cord-006870-f5w6fw6q 2785 3 were be VBD cord-006870-f5w6fw6q 2785 4 excluded exclude VBN cord-006870-f5w6fw6q 2785 5 from from IN cord-006870-f5w6fw6q 2785 6 the the DT cord-006870-f5w6fw6q 2785 7 study study NN cord-006870-f5w6fw6q 2785 8 because because IN cord-006870-f5w6fw6q 2785 9 of of IN cord-006870-f5w6fw6q 2785 10 presumed presumed JJ cord-006870-f5w6fw6q 2785 11 administration administration NN cord-006870-f5w6fw6q 2785 12 of of IN cord-006870-f5w6fw6q 2785 13 HSB HSB NNP cord-006870-f5w6fw6q 2785 14 through through IN cord-006870-f5w6fw6q 2785 15 central central JJ cord-006870-f5w6fw6q 2785 16 venous venous JJ cord-006870-f5w6fw6q 2785 17 access access NN cord-006870-f5w6fw6q 2785 18 , , , cord-006870-f5w6fw6q 2785 19 not not RB cord-006870-f5w6fw6q 2785 20 peripheral peripheral JJ cord-006870-f5w6fw6q 2785 21 IV IV NNP cord-006870-f5w6fw6q 2785 22 . . . cord-006870-f5w6fw6q 2786 1 Two two CD cord-006870-f5w6fw6q 2786 2 patients patient NNS cord-006870-f5w6fw6q 2786 3 had have VBD cord-006870-f5w6fw6q 2786 4 adverse adverse JJ cord-006870-f5w6fw6q 2786 5 events event NNS cord-006870-f5w6fw6q 2786 6 ( ( -LRB- cord-006870-f5w6fw6q 2786 7 3.5 3.5 CD cord-006870-f5w6fw6q 2786 8 % % NN cord-006870-f5w6fw6q 2786 9 ) ) -RRB- cord-006870-f5w6fw6q 2786 10 . . . cord-006870-f5w6fw6q 2787 1 None none NN cord-006870-f5w6fw6q 2787 2 of of IN cord-006870-f5w6fw6q 2787 3 the the DT cord-006870-f5w6fw6q 2787 4 patients patient NNS cord-006870-f5w6fw6q 2787 5 progressed progress VBD cord-006870-f5w6fw6q 2787 6 toward toward IN cord-006870-f5w6fw6q 2787 7 limb limb NN cord-006870-f5w6fw6q 2787 8 threatening threaten VBG cord-006870-f5w6fw6q 2787 9 complications complication NNS cord-006870-f5w6fw6q 2787 10 . . . cord-006870-f5w6fw6q 2788 1 The the DT cord-006870-f5w6fw6q 2788 2 majority majority NN cord-006870-f5w6fw6q 2788 3 of of IN cord-006870-f5w6fw6q 2788 4 patients patient NNS cord-006870-f5w6fw6q 2788 5 ( ( -LRB- cord-006870-f5w6fw6q 2788 6 54/56 54/56 CD cord-006870-f5w6fw6q 2788 7 ) ) -RRB- cord-006870-f5w6fw6q 2788 8 did do VBD cord-006870-f5w6fw6q 2788 9 not not RB cord-006870-f5w6fw6q 2788 10 experience experience VB cord-006870-f5w6fw6q 2788 11 erythema erythema NN cord-006870-f5w6fw6q 2788 12 or or CC cord-006870-f5w6fw6q 2788 13 infiltration infiltration NN cord-006870-f5w6fw6q 2788 14 of of IN cord-006870-f5w6fw6q 2788 15 the the DT cord-006870-f5w6fw6q 2788 16 IV IV NNP cord-006870-f5w6fw6q 2788 17 . . . cord-006870-f5w6fw6q 2789 1 HSB HSB NNP cord-006870-f5w6fw6q 2789 2 administered administer VBD cord-006870-f5w6fw6q 2789 3 through through IN cord-006870-f5w6fw6q 2789 4 peripheral peripheral JJ cord-006870-f5w6fw6q 2789 5 intravenous intravenous JJ cord-006870-f5w6fw6q 2789 6 access access NN cord-006870-f5w6fw6q 2789 7 does do VBZ cord-006870-f5w6fw6q 2789 8 not not RB cord-006870-f5w6fw6q 2789 9 pose pose VB cord-006870-f5w6fw6q 2789 10 significant significant JJ cord-006870-f5w6fw6q 2789 11 risk risk NN cord-006870-f5w6fw6q 2789 12 of of IN cord-006870-f5w6fw6q 2789 13 severe severe JJ cord-006870-f5w6fw6q 2789 14 complications complication NNS cord-006870-f5w6fw6q 2789 15 and and CC cord-006870-f5w6fw6q 2789 16 may may MD cord-006870-f5w6fw6q 2789 17 be be VB cord-006870-f5w6fw6q 2789 18 safely safely RB cord-006870-f5w6fw6q 2789 19 used use VBN cord-006870-f5w6fw6q 2789 20 in in IN cord-006870-f5w6fw6q 2789 21 emergency emergency NN cord-006870-f5w6fw6q 2789 22 situations situation NNS cord-006870-f5w6fw6q 2789 23 in in IN cord-006870-f5w6fw6q 2789 24 the the DT cord-006870-f5w6fw6q 2789 25 absence absence NN cord-006870-f5w6fw6q 2789 26 of of IN cord-006870-f5w6fw6q 2789 27 central central JJ cord-006870-f5w6fw6q 2789 28 line line NN cord-006870-f5w6fw6q 2789 29 access access NN cord-006870-f5w6fw6q 2789 30 . . . cord-006870-f5w6fw6q 2790 1 Routine routine JJ cord-006870-f5w6fw6q 2790 2 screening screening NN cord-006870-f5w6fw6q 2790 3 of of IN cord-006870-f5w6fw6q 2790 4 high high JJ cord-006870-f5w6fw6q 2790 5 risk risk NN cord-006870-f5w6fw6q 2790 6 asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 2790 7 trauma trauma NN cord-006870-f5w6fw6q 2790 8 or or CC cord-006870-f5w6fw6q 2790 9 surgical surgical JJ cord-006870-f5w6fw6q 2790 10 patients patient NNS cord-006870-f5w6fw6q 2790 11 for for IN cord-006870-f5w6fw6q 2790 12 venous venous JJ cord-006870-f5w6fw6q 2790 13 thromboembolism(VTE thromboembolism(vte XX cord-006870-f5w6fw6q 2790 14 ) ) -RRB- cord-006870-f5w6fw6q 2790 15 is be VBZ cord-006870-f5w6fw6q 2790 16 controversial controversial JJ cord-006870-f5w6fw6q 2790 17 . . . cord-006870-f5w6fw6q 2791 1 Studies study NNS cord-006870-f5w6fw6q 2791 2 suggest suggest VBP cord-006870-f5w6fw6q 2791 3 against against IN cord-006870-f5w6fw6q 2791 4 screening screening NN cord-006870-f5w6fw6q 2791 5 while while IN cord-006870-f5w6fw6q 2791 6 others other NNS cord-006870-f5w6fw6q 2791 7 recognize recognize VBP cord-006870-f5w6fw6q 2791 8 that that IN cord-006870-f5w6fw6q 2791 9 some some DT cord-006870-f5w6fw6q 2791 10 patients patient NNS cord-006870-f5w6fw6q 2791 11 at at IN cord-006870-f5w6fw6q 2791 12 high high JJ cord-006870-f5w6fw6q 2791 13 risk risk NN cord-006870-f5w6fw6q 2791 14 may may MD cord-006870-f5w6fw6q 2791 15 benefit benefit VB cord-006870-f5w6fw6q 2791 16 . . . cord-006870-f5w6fw6q 2792 1 The the DT cord-006870-f5w6fw6q 2792 2 purpose purpose NN cord-006870-f5w6fw6q 2792 3 of of IN cord-006870-f5w6fw6q 2792 4 this this DT cord-006870-f5w6fw6q 2792 5 pilot pilot NN cord-006870-f5w6fw6q 2792 6 study study NN cord-006870-f5w6fw6q 2792 7 is be VBZ cord-006870-f5w6fw6q 2792 8 to to TO cord-006870-f5w6fw6q 2792 9 evaluate evaluate VB cord-006870-f5w6fw6q 2792 10 the the DT cord-006870-f5w6fw6q 2792 11 outcome outcome NN cord-006870-f5w6fw6q 2792 12 of of IN cord-006870-f5w6fw6q 2792 13 routine routine JJ cord-006870-f5w6fw6q 2792 14 screening screening NN cord-006870-f5w6fw6q 2792 15 in in IN cord-006870-f5w6fw6q 2792 16 patients patient NNS cord-006870-f5w6fw6q 2792 17 who who WP cord-006870-f5w6fw6q 2792 18 underwent undergo VBD cord-006870-f5w6fw6q 2792 19 neuro neuro JJ cord-006870-f5w6fw6q 2792 20 - - HYPH cord-006870-f5w6fw6q 2792 21 surgical surgical JJ cord-006870-f5w6fw6q 2792 22 interventions intervention NNS cord-006870-f5w6fw6q 2792 23 . . . cord-006870-f5w6fw6q 2793 1 All all DT cord-006870-f5w6fw6q 2793 2 adult adult NN cord-006870-f5w6fw6q 2793 3 patients patient NNS cord-006870-f5w6fw6q 2793 4 admitted admit VBD cord-006870-f5w6fw6q 2793 5 to to IN cord-006870-f5w6fw6q 2793 6 a a DT cord-006870-f5w6fw6q 2793 7 neuro neuro JJ cord-006870-f5w6fw6q 2793 8 - - HYPH cord-006870-f5w6fw6q 2793 9 intensive intensive JJ cord-006870-f5w6fw6q 2793 10 care care NN cord-006870-f5w6fw6q 2793 11 unit unit NN cord-006870-f5w6fw6q 2793 12 with with IN cord-006870-f5w6fw6q 2793 13 a a DT cord-006870-f5w6fw6q 2793 14 primary primary JJ cord-006870-f5w6fw6q 2793 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 2793 16 of of IN cord-006870-f5w6fw6q 2793 17 brain brain NN cord-006870-f5w6fw6q 2793 18 injury injury NN cord-006870-f5w6fw6q 2793 19 requiring require VBG cord-006870-f5w6fw6q 2793 20 surgical surgical JJ cord-006870-f5w6fw6q 2793 21 interventions intervention NNS cord-006870-f5w6fw6q 2793 22 were be VBD cord-006870-f5w6fw6q 2793 23 included include VBN cord-006870-f5w6fw6q 2793 24 . . . cord-006870-f5w6fw6q 2794 1 Data datum NNS cord-006870-f5w6fw6q 2794 2 from from IN cord-006870-f5w6fw6q 2794 3 April April NNP cord-006870-f5w6fw6q 2794 4 - - HYPH cord-006870-f5w6fw6q 2794 5 June June NNP cord-006870-f5w6fw6q 2794 6 , , , cord-006870-f5w6fw6q 2794 7 2017 2017 CD cord-006870-f5w6fw6q 2794 8 were be VBD cord-006870-f5w6fw6q 2794 9 retrospectively retrospectively RB cord-006870-f5w6fw6q 2794 10 collected collect VBN cord-006870-f5w6fw6q 2794 11 on on IN cord-006870-f5w6fw6q 2794 12 all all DT cord-006870-f5w6fw6q 2794 13 subjects subject NNS cord-006870-f5w6fw6q 2794 14 who who WP cord-006870-f5w6fw6q 2794 15 had have VBD cord-006870-f5w6fw6q 2794 16 either either CC cord-006870-f5w6fw6q 2794 17 spine spine NN cord-006870-f5w6fw6q 2794 18 or or CC cord-006870-f5w6fw6q 2794 19 cranial cranial JJ cord-006870-f5w6fw6q 2794 20 surgery surgery NN cord-006870-f5w6fw6q 2794 21 . . . cord-006870-f5w6fw6q 2795 1 Data datum NNS cord-006870-f5w6fw6q 2795 2 collected collect VBN cord-006870-f5w6fw6q 2795 3 include include VBP cord-006870-f5w6fw6q 2795 4 : : : cord-006870-f5w6fw6q 2795 5 incidence incidence NN cord-006870-f5w6fw6q 2795 6 of of IN cord-006870-f5w6fw6q 2795 7 VTE VTE NNP cord-006870-f5w6fw6q 2795 8 , , , cord-006870-f5w6fw6q 2796 1 number number NN cord-006870-f5w6fw6q 2796 2 of of IN cord-006870-f5w6fw6q 2796 3 times time NNS cord-006870-f5w6fw6q 2796 4 duplex duplex NN cord-006870-f5w6fw6q 2796 5 ultrasonography ultrasonography NN cord-006870-f5w6fw6q 2796 6 and and CC cord-006870-f5w6fw6q 2796 7 computed compute VBN cord-006870-f5w6fw6q 2796 8 tomography tomography NN cord-006870-f5w6fw6q 2796 9 of of IN cord-006870-f5w6fw6q 2796 10 the the DT cord-006870-f5w6fw6q 2796 11 chest chest NN cord-006870-f5w6fw6q 2796 12 was be VBD cord-006870-f5w6fw6q 2796 13 performed perform VBN cord-006870-f5w6fw6q 2796 14 . . . cord-006870-f5w6fw6q 2797 1 On on IN cord-006870-f5w6fw6q 2797 2 July July NNP cord-006870-f5w6fw6q 2797 3 1st 1st NN cord-006870-f5w6fw6q 2797 4 , , , cord-006870-f5w6fw6q 2797 5 prospective prospective JJ cord-006870-f5w6fw6q 2797 6 data data NN cord-006870-f5w6fw6q 2797 7 collection collection NN cord-006870-f5w6fw6q 2797 8 began begin VBD cord-006870-f5w6fw6q 2797 9 by by IN cord-006870-f5w6fw6q 2797 10 screening screen VBG cord-006870-f5w6fw6q 2797 11 for for IN cord-006870-f5w6fw6q 2797 12 presence presence NN cord-006870-f5w6fw6q 2797 13 of of IN cord-006870-f5w6fw6q 2797 14 deep deep JJ cord-006870-f5w6fw6q 2797 15 vein vein NN cord-006870-f5w6fw6q 2797 16 thrombosis(DVT thrombosis(dvt ADD cord-006870-f5w6fw6q 2797 17 ) ) -RRB- cord-006870-f5w6fw6q 2797 18 on on IN cord-006870-f5w6fw6q 2797 19 day day NN cord-006870-f5w6fw6q 2797 20 1 1 CD cord-006870-f5w6fw6q 2797 21 , , , cord-006870-f5w6fw6q 2797 22 7 7 CD cord-006870-f5w6fw6q 2797 23 and and CC cord-006870-f5w6fw6q 2797 24 14 14 CD cord-006870-f5w6fw6q 2797 25 from from IN cord-006870-f5w6fw6q 2797 26 admission admission NN cord-006870-f5w6fw6q 2797 27 or or CC cord-006870-f5w6fw6q 2797 28 surgery surgery NN cord-006870-f5w6fw6q 2797 29 day day NN cord-006870-f5w6fw6q 2797 30 . . . cord-006870-f5w6fw6q 2798 1 All all DT cord-006870-f5w6fw6q 2798 2 patients patient NNS cord-006870-f5w6fw6q 2798 3 received receive VBD cord-006870-f5w6fw6q 2798 4 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 2798 5 and and CC cord-006870-f5w6fw6q 2798 6 mechanical mechanical JJ cord-006870-f5w6fw6q 2798 7 VTE VTE NNP cord-006870-f5w6fw6q 2798 8 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2798 9 within within IN cord-006870-f5w6fw6q 2798 10 36 36 CD cord-006870-f5w6fw6q 2798 11 - - SYM cord-006870-f5w6fw6q 2798 12 48 48 CD cord-006870-f5w6fw6q 2798 13 hours hour NNS cord-006870-f5w6fw6q 2798 14 post post NN cord-006870-f5w6fw6q 2798 15 - - JJ cord-006870-f5w6fw6q 2798 16 operatively operatively RB cord-006870-f5w6fw6q 2798 17 . . . cord-006870-f5w6fw6q 2799 1 A a DT cord-006870-f5w6fw6q 2799 2 total total NN cord-006870-f5w6fw6q 2799 3 of of IN cord-006870-f5w6fw6q 2799 4 101 101 CD cord-006870-f5w6fw6q 2799 5 ( ( -LRB- cord-006870-f5w6fw6q 2799 6 pre pre NN cord-006870-f5w6fw6q 2799 7 - - JJ cord-006870-f5w6fw6q 2799 8 pilot pilot JJ cord-006870-f5w6fw6q 2799 9 , , , cord-006870-f5w6fw6q 2799 10 n=91 n=91 NNP cord-006870-f5w6fw6q 2799 11 and and CC cord-006870-f5w6fw6q 2799 12 post post NN cord-006870-f5w6fw6q 2799 13 - - JJ cord-006870-f5w6fw6q 2799 14 pilot pilot JJ cord-006870-f5w6fw6q 2799 15 , , , cord-006870-f5w6fw6q 2799 16 n=10 n=10 NNP cord-006870-f5w6fw6q 2799 17 ) ) -RRB- cord-006870-f5w6fw6q 2799 18 subjects subject NNS cord-006870-f5w6fw6q 2799 19 were be VBD cord-006870-f5w6fw6q 2799 20 included include VBN cord-006870-f5w6fw6q 2799 21 in in IN cord-006870-f5w6fw6q 2799 22 the the DT cord-006870-f5w6fw6q 2799 23 study study NN cord-006870-f5w6fw6q 2799 24 . . . cord-006870-f5w6fw6q 2800 1 In in IN cord-006870-f5w6fw6q 2800 2 the the DT cord-006870-f5w6fw6q 2800 3 pre pre JJ cord-006870-f5w6fw6q 2800 4 - - JJ cord-006870-f5w6fw6q 2800 5 pilot pilot JJ cord-006870-f5w6fw6q 2800 6 group group NN cord-006870-f5w6fw6q 2800 7 , , , cord-006870-f5w6fw6q 2800 8 the the DT cord-006870-f5w6fw6q 2800 9 ages age NNS cord-006870-f5w6fw6q 2800 10 ranged range VBD cord-006870-f5w6fw6q 2800 11 from from IN cord-006870-f5w6fw6q 2800 12 18 18 CD cord-006870-f5w6fw6q 2800 13 - - SYM cord-006870-f5w6fw6q 2800 14 70 70 CD cord-006870-f5w6fw6q 2800 15 and and CC cord-006870-f5w6fw6q 2800 16 most most JJS cord-006870-f5w6fw6q 2800 17 were be VBD cord-006870-f5w6fw6q 2800 18 male male JJ cord-006870-f5w6fw6q 2800 19 . . . cord-006870-f5w6fw6q 2801 1 Majority majority NN cord-006870-f5w6fw6q 2801 2 , , , cord-006870-f5w6fw6q 2801 3 73/91(80 73/91(80 CD cord-006870-f5w6fw6q 2801 4 % % NN cord-006870-f5w6fw6q 2801 5 ) ) -RRB- cord-006870-f5w6fw6q 2801 6 had have VBD cord-006870-f5w6fw6q 2801 7 either either CC cord-006870-f5w6fw6q 2801 8 craniotomy craniotomy NN cord-006870-f5w6fw6q 2801 9 / / SYM cord-006870-f5w6fw6q 2801 10 craniectomy craniectomy NN cord-006870-f5w6fw6q 2801 11 while while IN cord-006870-f5w6fw6q 2801 12 18/91(20 18/91(20 CD cord-006870-f5w6fw6q 2801 13 % % NN cord-006870-f5w6fw6q 2801 14 ) ) -RRB- cord-006870-f5w6fw6q 2801 15 had have VBD cord-006870-f5w6fw6q 2801 16 spine spine NN cord-006870-f5w6fw6q 2801 17 surgery surgery NN cord-006870-f5w6fw6q 2801 18 . . . cord-006870-f5w6fw6q 2802 1 About about RB cord-006870-f5w6fw6q 2802 2 30/91(33 30/91(33 CD cord-006870-f5w6fw6q 2802 3 % % NN cord-006870-f5w6fw6q 2802 4 ) ) -RRB- cord-006870-f5w6fw6q 2802 5 were be VBD cord-006870-f5w6fw6q 2802 6 admitted admit VBN cord-006870-f5w6fw6q 2802 7 with with IN cord-006870-f5w6fw6q 2802 8 primary primary JJ cord-006870-f5w6fw6q 2802 9 diagnosis diagnosis NN cord-006870-f5w6fw6q 2802 10 of of IN cord-006870-f5w6fw6q 2802 11 traumatic traumatic JJ cord-006870-f5w6fw6q 2802 12 brain brain NN cord-006870-f5w6fw6q 2802 13 injury injury NN cord-006870-f5w6fw6q 2802 14 . . . cord-006870-f5w6fw6q 2803 1 Of of IN cord-006870-f5w6fw6q 2803 2 the the DT cord-006870-f5w6fw6q 2803 3 91 91 CD cord-006870-f5w6fw6q 2803 4 subjects subject NNS cord-006870-f5w6fw6q 2803 5 , , , cord-006870-f5w6fw6q 2803 6 35 35 CD cord-006870-f5w6fw6q 2803 7 had have VBD cord-006870-f5w6fw6q 2803 8 duplex duplex NN cord-006870-f5w6fw6q 2803 9 screening screening NN cord-006870-f5w6fw6q 2803 10 for for IN cord-006870-f5w6fw6q 2803 11 DVT DVT NNP cord-006870-f5w6fw6q 2803 12 and and CC cord-006870-f5w6fw6q 2803 13 8 8 CD cord-006870-f5w6fw6q 2803 14 had have VBD cord-006870-f5w6fw6q 2803 15 screening screening NN cord-006870-f5w6fw6q 2803 16 for for IN cord-006870-f5w6fw6q 2803 17 pulmonary pulmonary NNP cord-006870-f5w6fw6q 2803 18 embolism(PE embolism(PE NNP cord-006870-f5w6fw6q 2803 19 ) ) -RRB- cord-006870-f5w6fw6q 2803 20 . . . cord-006870-f5w6fw6q 2804 1 The the DT cord-006870-f5w6fw6q 2804 2 incidence incidence NN cord-006870-f5w6fw6q 2804 3 of of IN cord-006870-f5w6fw6q 2804 4 VTE VTE NNP cord-006870-f5w6fw6q 2804 5 was be VBD cord-006870-f5w6fw6q 2804 6 confirmed confirm VBN cord-006870-f5w6fw6q 2804 7 in in IN cord-006870-f5w6fw6q 2804 8 11/91(12 11/91(12 CD cord-006870-f5w6fw6q 2804 9 % % NN cord-006870-f5w6fw6q 2804 10 ) ) -RRB- cord-006870-f5w6fw6q 2804 11 ; ; : cord-006870-f5w6fw6q 2804 12 ( ( -LRB- cord-006870-f5w6fw6q 2804 13 DVT-8 DVT-8 VBG cord-006870-f5w6fw6q 2804 14 % % NN cord-006870-f5w6fw6q 2804 15 and and CC cord-006870-f5w6fw6q 2804 16 PE-4 PE-4 NNP cord-006870-f5w6fw6q 2804 17 % % NN cord-006870-f5w6fw6q 2804 18 ) ) -RRB- cord-006870-f5w6fw6q 2804 19 . . . cord-006870-f5w6fw6q 2805 1 Median median JJ cord-006870-f5w6fw6q 2805 2 hospital hospital NN cord-006870-f5w6fw6q 2805 3 length length NN cord-006870-f5w6fw6q 2805 4 of of IN cord-006870-f5w6fw6q 2805 5 stay stay NN cord-006870-f5w6fw6q 2805 6 was be VBD cord-006870-f5w6fw6q 2805 7 9 9 CD cord-006870-f5w6fw6q 2806 1 ( ( -LRB- cord-006870-f5w6fw6q 2806 2 IQR IQR NNP cord-006870-f5w6fw6q 2806 3 4 4 CD cord-006870-f5w6fw6q 2806 4 - - SYM cord-006870-f5w6fw6q 2806 5 15 15 CD cord-006870-f5w6fw6q 2806 6 ) ) -RRB- cord-006870-f5w6fw6q 2806 7 days day NNS cord-006870-f5w6fw6q 2806 8 . . . cord-006870-f5w6fw6q 2807 1 38/91(42 38/91(42 CD cord-006870-f5w6fw6q 2807 2 % % NN cord-006870-f5w6fw6q 2807 3 ) ) -RRB- cord-006870-f5w6fw6q 2807 4 were be VBD cord-006870-f5w6fw6q 2807 5 discharged discharge VBN cord-006870-f5w6fw6q 2807 6 home home NN cord-006870-f5w6fw6q 2807 7 and and CC cord-006870-f5w6fw6q 2807 8 2/91(2 2/91(2 CD cord-006870-f5w6fw6q 2807 9 % % NN cord-006870-f5w6fw6q 2807 10 ) ) -RRB- cord-006870-f5w6fw6q 2808 1 death death NN cord-006870-f5w6fw6q 2808 2 rate rate NN cord-006870-f5w6fw6q 2808 3 was be VBD cord-006870-f5w6fw6q 2808 4 attributed attribute VBN cord-006870-f5w6fw6q 2808 5 to to IN cord-006870-f5w6fw6q 2808 6 PE PE NNP cord-006870-f5w6fw6q 2808 7 . . . cord-006870-f5w6fw6q 2809 1 In in IN cord-006870-f5w6fw6q 2809 2 the the DT cord-006870-f5w6fw6q 2809 3 post post JJ cord-006870-f5w6fw6q 2809 4 - - JJ cord-006870-f5w6fw6q 2809 5 pilot pilot JJ cord-006870-f5w6fw6q 2809 6 group group NN cord-006870-f5w6fw6q 2809 7 , , , cord-006870-f5w6fw6q 2809 8 one one CD cord-006870-f5w6fw6q 2809 9 incidence incidence NN cord-006870-f5w6fw6q 2809 10 of of IN cord-006870-f5w6fw6q 2809 11 PE PE NNP cord-006870-f5w6fw6q 2809 12 was be VBD cord-006870-f5w6fw6q 2809 13 identified identify VBN cord-006870-f5w6fw6q 2809 14 on on IN cord-006870-f5w6fw6q 2809 15 day day NN cord-006870-f5w6fw6q 2809 16 1 1 CD cord-006870-f5w6fw6q 2809 17 post post NN cord-006870-f5w6fw6q 2809 18 surgery surgery NN cord-006870-f5w6fw6q 2809 19 screening screening NN cord-006870-f5w6fw6q 2809 20 . . . cord-006870-f5w6fw6q 2810 1 The the DT cord-006870-f5w6fw6q 2810 2 rest rest NN cord-006870-f5w6fw6q 2810 3 of of IN cord-006870-f5w6fw6q 2810 4 the the DT cord-006870-f5w6fw6q 2810 5 results result NNS cord-006870-f5w6fw6q 2810 6 are be VBP cord-006870-f5w6fw6q 2810 7 still still RB cord-006870-f5w6fw6q 2810 8 pending pende VBG cord-006870-f5w6fw6q 2810 9 . . . cord-006870-f5w6fw6q 2811 1 In in IN cord-006870-f5w6fw6q 2811 2 this this DT cord-006870-f5w6fw6q 2811 3 preliminary preliminary JJ cord-006870-f5w6fw6q 2811 4 report report NN cord-006870-f5w6fw6q 2811 5 , , , cord-006870-f5w6fw6q 2811 6 post post VB cord-006870-f5w6fw6q 2811 7 surgical surgical JJ cord-006870-f5w6fw6q 2811 8 patients patient NNS cord-006870-f5w6fw6q 2811 9 have have VBP cord-006870-f5w6fw6q 2811 10 a a DT cord-006870-f5w6fw6q 2811 11 higher high JJR cord-006870-f5w6fw6q 2811 12 incidence incidence NN cord-006870-f5w6fw6q 2811 13 of of IN cord-006870-f5w6fw6q 2811 14 VTE VTE NNP cord-006870-f5w6fw6q 2811 15 . . . cord-006870-f5w6fw6q 2812 1 Routine routine JJ cord-006870-f5w6fw6q 2812 2 screening screening NN cord-006870-f5w6fw6q 2812 3 might may MD cord-006870-f5w6fw6q 2812 4 benefit benefit VB cord-006870-f5w6fw6q 2812 5 to to TO cord-006870-f5w6fw6q 2812 6 lower lower VB cord-006870-f5w6fw6q 2812 7 the the DT cord-006870-f5w6fw6q 2812 8 incidence incidence NN cord-006870-f5w6fw6q 2812 9 of of IN cord-006870-f5w6fw6q 2812 10 mortality mortality NN cord-006870-f5w6fw6q 2812 11 caused cause VBN cord-006870-f5w6fw6q 2812 12 by by IN cord-006870-f5w6fw6q 2812 13 PE PE NNP cord-006870-f5w6fw6q 2812 14 . . . cord-006870-f5w6fw6q 2813 1 Epsilon Epsilon NNP cord-006870-f5w6fw6q 2813 2 aminocaproic aminocaproic NNP cord-006870-f5w6fw6q 2813 3 acid acid NN cord-006870-f5w6fw6q 2813 4 ( ( -LRB- cord-006870-f5w6fw6q 2813 5 EACA EACA NNP cord-006870-f5w6fw6q 2813 6 ) ) -RRB- cord-006870-f5w6fw6q 2813 7 is be VBZ cord-006870-f5w6fw6q 2813 8 an an DT cord-006870-f5w6fw6q 2813 9 antifibrinolytic antifibrinolytic JJ cord-006870-f5w6fw6q 2813 10 agent agent NN cord-006870-f5w6fw6q 2813 11 that that WDT cord-006870-f5w6fw6q 2813 12 crosses cross VBZ cord-006870-f5w6fw6q 2813 13 the the DT cord-006870-f5w6fw6q 2813 14 blood blood NN cord-006870-f5w6fw6q 2813 15 - - HYPH cord-006870-f5w6fw6q 2813 16 brain brain NN cord-006870-f5w6fw6q 2813 17 barrier barrier NN cord-006870-f5w6fw6q 2813 18 and and CC cord-006870-f5w6fw6q 2813 19 has have VBZ cord-006870-f5w6fw6q 2813 20 shown show VBN cord-006870-f5w6fw6q 2813 21 benefit benefit NN cord-006870-f5w6fw6q 2813 22 in in IN cord-006870-f5w6fw6q 2813 23 decreasing decrease VBG cord-006870-f5w6fw6q 2813 24 bleeding bleed VBG cord-006870-f5w6fw6q 2813 25 in in IN cord-006870-f5w6fw6q 2813 26 patients patient NNS cord-006870-f5w6fw6q 2813 27 acutely acutely RB cord-006870-f5w6fw6q 2813 28 . . . cord-006870-f5w6fw6q 2814 1 Its -PRON- PRP$ cord-006870-f5w6fw6q 2814 2 use use NN cord-006870-f5w6fw6q 2814 3 in in IN cord-006870-f5w6fw6q 2814 4 intracranial intracranial JJ cord-006870-f5w6fw6q 2814 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2814 6 has have VBZ cord-006870-f5w6fw6q 2814 7 uncertain uncertain JJ cord-006870-f5w6fw6q 2814 8 benefit benefit NN cord-006870-f5w6fw6q 2814 9 . . . cord-006870-f5w6fw6q 2815 1 We -PRON- PRP cord-006870-f5w6fw6q 2815 2 aimed aim VBD cord-006870-f5w6fw6q 2815 3 to to TO cord-006870-f5w6fw6q 2815 4 describe describe VB cord-006870-f5w6fw6q 2815 5 the the DT cord-006870-f5w6fw6q 2815 6 administration administration NN cord-006870-f5w6fw6q 2815 7 and and CC cord-006870-f5w6fw6q 2815 8 impact impact NN cord-006870-f5w6fw6q 2815 9 of of IN cord-006870-f5w6fw6q 2815 10 EACA EACA NNS cord-006870-f5w6fw6q 2815 11 in in IN cord-006870-f5w6fw6q 2815 12 a a DT cord-006870-f5w6fw6q 2815 13 single single JJ cord-006870-f5w6fw6q 2815 14 - - HYPH cord-006870-f5w6fw6q 2815 15 center center NN cord-006870-f5w6fw6q 2815 16 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 2815 17 Intensive Intensive NNP cord-006870-f5w6fw6q 2815 18 Care Care NNP cord-006870-f5w6fw6q 2815 19 Unit Unit NNP cord-006870-f5w6fw6q 2815 20 ( ( -LRB- cord-006870-f5w6fw6q 2815 21 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 2815 22 ) ) -RRB- cord-006870-f5w6fw6q 2815 23 over over IN cord-006870-f5w6fw6q 2815 24 one one CD cord-006870-f5w6fw6q 2815 25 year year NN cord-006870-f5w6fw6q 2815 26 . . . cord-006870-f5w6fw6q 2816 1 We -PRON- PRP cord-006870-f5w6fw6q 2816 2 performed perform VBD cord-006870-f5w6fw6q 2816 3 a a DT cord-006870-f5w6fw6q 2816 4 single single JJ cord-006870-f5w6fw6q 2816 5 - - HYPH cord-006870-f5w6fw6q 2816 6 center center NN cord-006870-f5w6fw6q 2816 7 retrospective retrospective JJ cord-006870-f5w6fw6q 2816 8 study study NN cord-006870-f5w6fw6q 2816 9 of of IN cord-006870-f5w6fw6q 2816 10 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 2816 11 patients patient NNS cord-006870-f5w6fw6q 2816 12 undergoing undergo VBG cord-006870-f5w6fw6q 2816 13 intravenous intravenous JJ cord-006870-f5w6fw6q 2816 14 EACA EACA NNP cord-006870-f5w6fw6q 2816 15 administration administration NN cord-006870-f5w6fw6q 2816 16 over over IN cord-006870-f5w6fw6q 2816 17 a a DT cord-006870-f5w6fw6q 2816 18 one one CD cord-006870-f5w6fw6q 2816 19 - - HYPH cord-006870-f5w6fw6q 2816 20 year year NN cord-006870-f5w6fw6q 2816 21 time time NN cord-006870-f5w6fw6q 2816 22 period period NN cord-006870-f5w6fw6q 2816 23 . . . cord-006870-f5w6fw6q 2817 1 Inclusion inclusion NN cord-006870-f5w6fw6q 2817 2 criteria criterion NNS cord-006870-f5w6fw6q 2817 3 included include VBD cord-006870-f5w6fw6q 2817 4 EACA EACA NNP cord-006870-f5w6fw6q 2817 5 administration administration NN cord-006870-f5w6fw6q 2817 6 over over IN cord-006870-f5w6fw6q 2817 7 24 24 CD cord-006870-f5w6fw6q 2817 8 hours hour NNS cord-006870-f5w6fw6q 2817 9 for for IN cord-006870-f5w6fw6q 2817 10 a a DT cord-006870-f5w6fw6q 2817 11 diagnosis diagnosis NN cord-006870-f5w6fw6q 2817 12 of of IN cord-006870-f5w6fw6q 2817 13 acute acute JJ cord-006870-f5w6fw6q 2817 14 traumatic traumatic JJ cord-006870-f5w6fw6q 2817 15 hematoma hematoma NN cord-006870-f5w6fw6q 2817 16 . . . cord-006870-f5w6fw6q 2818 1 The the DT cord-006870-f5w6fw6q 2818 2 dose dose NN cord-006870-f5w6fw6q 2818 3 and and CC cord-006870-f5w6fw6q 2818 4 duration duration NN cord-006870-f5w6fw6q 2818 5 of of IN cord-006870-f5w6fw6q 2818 6 EACA EACA NNP cord-006870-f5w6fw6q 2818 7 infusion infusion NN cord-006870-f5w6fw6q 2818 8 was be VBD cord-006870-f5w6fw6q 2818 9 collected collect VBN cord-006870-f5w6fw6q 2818 10 . . . cord-006870-f5w6fw6q 2819 1 We -PRON- PRP cord-006870-f5w6fw6q 2819 2 additionally additionally RB cord-006870-f5w6fw6q 2819 3 collected collect VBD cord-006870-f5w6fw6q 2819 4 and and CC cord-006870-f5w6fw6q 2819 5 compared compare VBN cord-006870-f5w6fw6q 2819 6 pre pre JJ cord-006870-f5w6fw6q 2819 7 - - JJ cord-006870-f5w6fw6q 2819 8 administration administration JJ cord-006870-f5w6fw6q 2819 9 and and CC cord-006870-f5w6fw6q 2819 10 post post JJ cord-006870-f5w6fw6q 2819 11 - - JJ cord-006870-f5w6fw6q 2819 12 administration administration JJ cord-006870-f5w6fw6q 2819 13 prolonged prolong VBN cord-006870-f5w6fw6q 2819 14 thromboplastin thromboplastin NNP cord-006870-f5w6fw6q 2819 15 time time NN cord-006870-f5w6fw6q 2819 16 ( ( -LRB- cord-006870-f5w6fw6q 2819 17 PTT PTT NNP cord-006870-f5w6fw6q 2819 18 ) ) -RRB- cord-006870-f5w6fw6q 2819 19 hematology hematology NN cord-006870-f5w6fw6q 2819 20 assays assay NNS cord-006870-f5w6fw6q 2819 21 and and CC cord-006870-f5w6fw6q 2819 22 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 2819 23 . . . cord-006870-f5w6fw6q 2820 1 Clinical clinical JJ cord-006870-f5w6fw6q 2820 2 outcomes outcome NNS cord-006870-f5w6fw6q 2820 3 were be VBD cord-006870-f5w6fw6q 2820 4 reviewed review VBN cord-006870-f5w6fw6q 2820 5 for for IN cord-006870-f5w6fw6q 2820 6 survival survival NN cord-006870-f5w6fw6q 2820 7 at at IN cord-006870-f5w6fw6q 2820 8 hospital hospital NN cord-006870-f5w6fw6q 2820 9 discharge discharge NN cord-006870-f5w6fw6q 2820 10 . . . cord-006870-f5w6fw6q 2821 1 Over over IN cord-006870-f5w6fw6q 2821 2 a a DT cord-006870-f5w6fw6q 2821 3 13-month 13-month JJ cord-006870-f5w6fw6q 2821 4 period period NN cord-006870-f5w6fw6q 2821 5 ( ( -LRB- cord-006870-f5w6fw6q 2821 6 April April NNP cord-006870-f5w6fw6q 2821 7 2016-May 2016-may CD cord-006870-f5w6fw6q 2821 8 2017 2017 CD cord-006870-f5w6fw6q 2821 9 ) ) -RRB- cord-006870-f5w6fw6q 2821 10 , , , cord-006870-f5w6fw6q 2821 11 24 24 CD cord-006870-f5w6fw6q 2821 12 patients patient NNS cord-006870-f5w6fw6q 2821 13 each each DT cord-006870-f5w6fw6q 2821 14 received receive VBD cord-006870-f5w6fw6q 2821 15 a a DT cord-006870-f5w6fw6q 2821 16 24-hour 24-hour JJ cord-006870-f5w6fw6q 2821 17 infusion infusion NN cord-006870-f5w6fw6q 2821 18 of of IN cord-006870-f5w6fw6q 2821 19 EACA EACA NNS cord-006870-f5w6fw6q 2821 20 . . . cord-006870-f5w6fw6q 2822 1 The the DT cord-006870-f5w6fw6q 2822 2 most most RBS cord-006870-f5w6fw6q 2822 3 common common JJ cord-006870-f5w6fw6q 2822 4 indication indication NN cord-006870-f5w6fw6q 2822 5 for for IN cord-006870-f5w6fw6q 2822 6 EACA EACA NNP cord-006870-f5w6fw6q 2822 7 was be VBD cord-006870-f5w6fw6q 2822 8 to to TO cord-006870-f5w6fw6q 2822 9 prevent prevent VB cord-006870-f5w6fw6q 2822 10 worsening worsen VBG cord-006870-f5w6fw6q 2822 11 of of IN cord-006870-f5w6fw6q 2822 12 intracranial intracranial JJ cord-006870-f5w6fw6q 2822 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2822 14 in in IN cord-006870-f5w6fw6q 2822 15 patients patient NNS cord-006870-f5w6fw6q 2822 16 in in IN cord-006870-f5w6fw6q 2822 17 traumatic traumatic JJ cord-006870-f5w6fw6q 2822 18 coma coma NN cord-006870-f5w6fw6q 2822 19 ( ( -LRB- cord-006870-f5w6fw6q 2823 1 GCS GCS NNP cord-006870-f5w6fw6q 2823 2 < < XX cord-006870-f5w6fw6q 2823 3 8) 8) NNP cord-006870-f5w6fw6q 2823 4 . . . cord-006870-f5w6fw6q 2824 1 68 68 CD cord-006870-f5w6fw6q 2824 2 % % NN cord-006870-f5w6fw6q 2824 3 of of IN cord-006870-f5w6fw6q 2824 4 patients patient NNS cord-006870-f5w6fw6q 2824 5 underwent undergo VBD cord-006870-f5w6fw6q 2824 6 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 2824 7 management management NN cord-006870-f5w6fw6q 2824 8 . . . cord-006870-f5w6fw6q 2825 1 PTT PTT NNP cord-006870-f5w6fw6q 2825 2 assay assay NN cord-006870-f5w6fw6q 2825 3 values value NNS cord-006870-f5w6fw6q 2825 4 showed show VBD cord-006870-f5w6fw6q 2825 5 a a DT cord-006870-f5w6fw6q 2825 6 significant significant JJ cord-006870-f5w6fw6q 2825 7 difference difference NN cord-006870-f5w6fw6q 2825 8 before before IN cord-006870-f5w6fw6q 2825 9 and and CC cord-006870-f5w6fw6q 2825 10 after after IN cord-006870-f5w6fw6q 2825 11 EACA EACA NNP cord-006870-f5w6fw6q 2825 12 administration administration NN cord-006870-f5w6fw6q 2825 13 . . . cord-006870-f5w6fw6q 2826 1 ( ( -LRB- cord-006870-f5w6fw6q 2826 2 PTT PTT NNP cord-006870-f5w6fw6q 2826 3 30.3+/-SD 30.3+/-sd CD cord-006870-f5w6fw6q 2826 4 vs. vs. IN cord-006870-f5w6fw6q 2826 5 28.6+/-SD 28.6+/-sd CD cord-006870-f5w6fw6q 2826 6 ; ; , cord-006870-f5w6fw6q 2826 7 student student NN cord-006870-f5w6fw6q 2826 8 's 's POS cord-006870-f5w6fw6q 2826 9 t t NN cord-006870-f5w6fw6q 2826 10 test test NN cord-006870-f5w6fw6q 2826 11 p<0.05 p<0.05 NNP cord-006870-f5w6fw6q 2826 12 , , , cord-006870-f5w6fw6q 2826 13 n=21 n=21 NNP cord-006870-f5w6fw6q 2826 14 ) ) -RRB- cord-006870-f5w6fw6q 2826 15 . . . cord-006870-f5w6fw6q 2827 1 Stability stability NN cord-006870-f5w6fw6q 2827 2 of of IN cord-006870-f5w6fw6q 2827 3 the the DT cord-006870-f5w6fw6q 2827 4 intracranial intracranial JJ cord-006870-f5w6fw6q 2827 5 hematoma hematoma NN cord-006870-f5w6fw6q 2827 6 burden burden NN cord-006870-f5w6fw6q 2827 7 was be VBD cord-006870-f5w6fw6q 2827 8 evident evident JJ cord-006870-f5w6fw6q 2827 9 following follow VBG cord-006870-f5w6fw6q 2827 10 EACA EACA NNS cord-006870-f5w6fw6q 2827 11 in in IN cord-006870-f5w6fw6q 2827 12 63 63 CD cord-006870-f5w6fw6q 2827 13 % % NN cord-006870-f5w6fw6q 2827 14 of of IN cord-006870-f5w6fw6q 2827 15 patients patient NNS cord-006870-f5w6fw6q 2827 16 . . . cord-006870-f5w6fw6q 2828 1 29 29 CD cord-006870-f5w6fw6q 2828 2 % % NN cord-006870-f5w6fw6q 2828 3 of of IN cord-006870-f5w6fw6q 2828 4 patients patient NNS cord-006870-f5w6fw6q 2828 5 who who WP cord-006870-f5w6fw6q 2828 6 received receive VBD cord-006870-f5w6fw6q 2828 7 EACA EACA NNP cord-006870-f5w6fw6q 2828 8 survived survive VBD cord-006870-f5w6fw6q 2828 9 to to TO cord-006870-f5w6fw6q 2828 10 discharge discharge VB cord-006870-f5w6fw6q 2828 11 . . . cord-006870-f5w6fw6q 2829 1 Patients patient NNS cord-006870-f5w6fw6q 2829 2 receiving receive VBG cord-006870-f5w6fw6q 2829 3 EACA EACA NNS cord-006870-f5w6fw6q 2829 4 showed show VBD cord-006870-f5w6fw6q 2829 5 a a DT cord-006870-f5w6fw6q 2829 6 significant significant JJ cord-006870-f5w6fw6q 2829 7 reduction reduction NN cord-006870-f5w6fw6q 2829 8 in in IN cord-006870-f5w6fw6q 2829 9 PTT PTT NNP cord-006870-f5w6fw6q 2829 10 assay assay NN cord-006870-f5w6fw6q 2829 11 values value VBZ cord-006870-f5w6fw6q 2829 12 24 24 CD cord-006870-f5w6fw6q 2829 13 hours hour NNS cord-006870-f5w6fw6q 2829 14 after after IN cord-006870-f5w6fw6q 2829 15 completing complete VBG cord-006870-f5w6fw6q 2829 16 their -PRON- PRP$ cord-006870-f5w6fw6q 2829 17 dose dose NN cord-006870-f5w6fw6q 2829 18 . . . cord-006870-f5w6fw6q 2830 1 CT CT NNP cord-006870-f5w6fw6q 2830 2 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 2830 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 2830 4 stable stable JJ cord-006870-f5w6fw6q 2830 5 intracranial intracranial JJ cord-006870-f5w6fw6q 2830 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2830 7 burden burden NN cord-006870-f5w6fw6q 2830 8 in in IN cord-006870-f5w6fw6q 2830 9 most most JJS cord-006870-f5w6fw6q 2830 10 patients patient NNS cord-006870-f5w6fw6q 2830 11 receiving receive VBG cord-006870-f5w6fw6q 2830 12 EACA EACA NNS cord-006870-f5w6fw6q 2830 13 despite despite IN cord-006870-f5w6fw6q 2830 14 a a DT cord-006870-f5w6fw6q 2830 15 high high JJ cord-006870-f5w6fw6q 2830 16 prevalence prevalence NN cord-006870-f5w6fw6q 2830 17 of of IN cord-006870-f5w6fw6q 2830 18 acute acute JJ cord-006870-f5w6fw6q 2830 19 operative operative JJ cord-006870-f5w6fw6q 2830 20 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 2830 21 management management NN cord-006870-f5w6fw6q 2830 22 . . . cord-006870-f5w6fw6q 2831 1 However however RB cord-006870-f5w6fw6q 2831 2 , , , cord-006870-f5w6fw6q 2831 3 only only RB cord-006870-f5w6fw6q 2831 4 a a DT cord-006870-f5w6fw6q 2831 5 modest modest JJ cord-006870-f5w6fw6q 2831 6 number number NN cord-006870-f5w6fw6q 2831 7 of of IN cord-006870-f5w6fw6q 2831 8 patients patient NNS cord-006870-f5w6fw6q 2831 9 receiving receive VBG cord-006870-f5w6fw6q 2831 10 EACA EACA NNS cord-006870-f5w6fw6q 2831 11 survived survive VBD cord-006870-f5w6fw6q 2831 12 to to TO cord-006870-f5w6fw6q 2831 13 discharge discharge VB cord-006870-f5w6fw6q 2831 14 . . . cord-006870-f5w6fw6q 2832 1 These these DT cord-006870-f5w6fw6q 2832 2 results result NNS cord-006870-f5w6fw6q 2832 3 suggest suggest VBP cord-006870-f5w6fw6q 2832 4 that that IN cord-006870-f5w6fw6q 2832 5 EACA EACA NNP cord-006870-f5w6fw6q 2832 6 may may MD cord-006870-f5w6fw6q 2832 7 acutely acutely RB cord-006870-f5w6fw6q 2832 8 reverse reverse VB cord-006870-f5w6fw6q 2832 9 hematologic hematologic JJ cord-006870-f5w6fw6q 2832 10 abnormalities abnormality NNS cord-006870-f5w6fw6q 2832 11 and and CC cord-006870-f5w6fw6q 2832 12 enable enable VB cord-006870-f5w6fw6q 2832 13 emergent emergent JJ cord-006870-f5w6fw6q 2832 14 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 2832 15 management management NN cord-006870-f5w6fw6q 2832 16 in in IN cord-006870-f5w6fw6q 2832 17 patients patient NNS cord-006870-f5w6fw6q 2832 18 with with IN cord-006870-f5w6fw6q 2832 19 severe severe JJ cord-006870-f5w6fw6q 2832 20 , , , cord-006870-f5w6fw6q 2832 21 acute acute JJ cord-006870-f5w6fw6q 2832 22 traumatic traumatic JJ cord-006870-f5w6fw6q 2832 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2832 24 , , , cord-006870-f5w6fw6q 2832 25 despite despite IN cord-006870-f5w6fw6q 2832 26 a a DT cord-006870-f5w6fw6q 2832 27 limited limited JJ cord-006870-f5w6fw6q 2832 28 role role NN cord-006870-f5w6fw6q 2832 29 in in IN cord-006870-f5w6fw6q 2832 30 affecting affect VBG cord-006870-f5w6fw6q 2832 31 survival survival NN cord-006870-f5w6fw6q 2832 32 outcomes outcome NNS cord-006870-f5w6fw6q 2832 33 in in IN cord-006870-f5w6fw6q 2832 34 these these DT cord-006870-f5w6fw6q 2832 35 patients patient NNS cord-006870-f5w6fw6q 2832 36 . . . cord-006870-f5w6fw6q 2833 1 Prognostication prognostication NN cord-006870-f5w6fw6q 2833 2 is be VBZ cord-006870-f5w6fw6q 2833 3 difficult difficult JJ cord-006870-f5w6fw6q 2833 4 for for IN cord-006870-f5w6fw6q 2833 5 patients patient NNS cord-006870-f5w6fw6q 2833 6 admitted admit VBN cord-006870-f5w6fw6q 2833 7 to to IN cord-006870-f5w6fw6q 2833 8 a a DT cord-006870-f5w6fw6q 2833 9 neurocritical neurocritical JJ cord-006870-f5w6fw6q 2833 10 care care NN cord-006870-f5w6fw6q 2833 11 unit unit NN cord-006870-f5w6fw6q 2833 12 ( ( -LRB- cord-006870-f5w6fw6q 2833 13 NCCU NCCU NNP cord-006870-f5w6fw6q 2833 14 ) ) -RRB- cord-006870-f5w6fw6q 2833 15 . . . cord-006870-f5w6fw6q 2834 1 Can Can MD cord-006870-f5w6fw6q 2834 2 serum serum NN cord-006870-f5w6fw6q 2834 3 biomarkers biomarker NNS cord-006870-f5w6fw6q 2834 4 obtained obtain VBN cord-006870-f5w6fw6q 2834 5 as as IN cord-006870-f5w6fw6q 2834 6 part part NN cord-006870-f5w6fw6q 2834 7 of of IN cord-006870-f5w6fw6q 2834 8 routine routine JJ cord-006870-f5w6fw6q 2834 9 admission admission NN cord-006870-f5w6fw6q 2834 10 lab lab NN cord-006870-f5w6fw6q 2834 11 work work NN cord-006870-f5w6fw6q 2834 12 help help MD cord-006870-f5w6fw6q 2834 13 predict predict VB cord-006870-f5w6fw6q 2834 14 outcomes outcome NNS cord-006870-f5w6fw6q 2834 15 among among IN cord-006870-f5w6fw6q 2834 16 patients patient NNS cord-006870-f5w6fw6q 2834 17 In in IN cord-006870-f5w6fw6q 2834 18 this this DT cord-006870-f5w6fw6q 2834 19 prospective prospective JJ cord-006870-f5w6fw6q 2834 20 cohort cohort NN cord-006870-f5w6fw6q 2834 21 study study NN cord-006870-f5w6fw6q 2834 22 , , , cord-006870-f5w6fw6q 2834 23 the the DT cord-006870-f5w6fw6q 2834 24 following follow VBG cord-006870-f5w6fw6q 2834 25 biomarkers biomarker NNS cord-006870-f5w6fw6q 2834 26 were be VBD cord-006870-f5w6fw6q 2834 27 measured measure VBN cord-006870-f5w6fw6q 2834 28 at at IN cord-006870-f5w6fw6q 2834 29 admission admission NN cord-006870-f5w6fw6q 2834 30 : : : cord-006870-f5w6fw6q 2834 31 C c NN cord-006870-f5w6fw6q 2834 32 - - HYPH cord-006870-f5w6fw6q 2834 33 reactive reactive JJ cord-006870-f5w6fw6q 2834 34 protein protein NN cord-006870-f5w6fw6q 2834 35 ( ( -LRB- cord-006870-f5w6fw6q 2834 36 CRP CRP NNP cord-006870-f5w6fw6q 2834 37 ) ) -RRB- cord-006870-f5w6fw6q 2834 38 , , , cord-006870-f5w6fw6q 2834 39 arterial arterial JJ cord-006870-f5w6fw6q 2834 40 lactate lactate NN cord-006870-f5w6fw6q 2834 41 , , , cord-006870-f5w6fw6q 2834 42 neuron neuron NN cord-006870-f5w6fw6q 2834 43 specific specific JJ cord-006870-f5w6fw6q 2834 44 enolase enolase NN cord-006870-f5w6fw6q 2834 45 ( ( -LRB- cord-006870-f5w6fw6q 2834 46 NSE NSE NNP cord-006870-f5w6fw6q 2834 47 ) ) -RRB- cord-006870-f5w6fw6q 2834 48 , , , cord-006870-f5w6fw6q 2834 49 lactate lactate NN cord-006870-f5w6fw6q 2834 50 dehydrogenase dehydrogenase NN cord-006870-f5w6fw6q 2834 51 ( ( -LRB- cord-006870-f5w6fw6q 2834 52 LDH LDH NNP cord-006870-f5w6fw6q 2834 53 ) ) -RRB- cord-006870-f5w6fw6q 2834 54 , , , cord-006870-f5w6fw6q 2834 55 albumin albumin NN cord-006870-f5w6fw6q 2834 56 , , , cord-006870-f5w6fw6q 2834 57 and and CC cord-006870-f5w6fw6q 2834 58 brain brain NN cord-006870-f5w6fw6q 2834 59 natriuretic natriuretic JJ cord-006870-f5w6fw6q 2834 60 peptide peptide NN cord-006870-f5w6fw6q 2834 61 ( ( -LRB- cord-006870-f5w6fw6q 2834 62 BNP BNP NNP cord-006870-f5w6fw6q 2834 63 ) ) -RRB- cord-006870-f5w6fw6q 2834 64 . . . cord-006870-f5w6fw6q 2835 1 We -PRON- PRP cord-006870-f5w6fw6q 2835 2 collected collect VBD cord-006870-f5w6fw6q 2835 3 information information NN cord-006870-f5w6fw6q 2835 4 about about IN cord-006870-f5w6fw6q 2835 5 demographics demographic NNS cord-006870-f5w6fw6q 2835 6 , , , cord-006870-f5w6fw6q 2835 7 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 2835 8 , , , cord-006870-f5w6fw6q 2835 9 hospital hospital NN cord-006870-f5w6fw6q 2835 10 procedures procedure NNS cord-006870-f5w6fw6q 2835 11 and and CC cord-006870-f5w6fw6q 2835 12 complications complication NNS cord-006870-f5w6fw6q 2835 13 and and CC cord-006870-f5w6fw6q 2835 14 30-day 30-day CD cord-006870-f5w6fw6q 2835 15 mortality mortality NN cord-006870-f5w6fw6q 2835 16 . . . cord-006870-f5w6fw6q 2836 1 We -PRON- PRP cord-006870-f5w6fw6q 2836 2 compared compare VBD cord-006870-f5w6fw6q 2836 3 these these DT cord-006870-f5w6fw6q 2836 4 serological serological JJ cord-006870-f5w6fw6q 2836 5 biomarkers biomarker NNS cord-006870-f5w6fw6q 2836 6 in in IN cord-006870-f5w6fw6q 2836 7 patients patient NNS cord-006870-f5w6fw6q 2836 8 who who WP cord-006870-f5w6fw6q 2836 9 were be VBD cord-006870-f5w6fw6q 2836 10 alive alive JJ cord-006870-f5w6fw6q 2836 11 versus versus IN cord-006870-f5w6fw6q 2836 12 those those DT cord-006870-f5w6fw6q 2836 13 who who WP cord-006870-f5w6fw6q 2836 14 had have VBD cord-006870-f5w6fw6q 2836 15 died die VBN cord-006870-f5w6fw6q 2836 16 at at IN cord-006870-f5w6fw6q 2836 17 30 30 CD cord-006870-f5w6fw6q 2836 18 days day NNS cord-006870-f5w6fw6q 2836 19 . . . cord-006870-f5w6fw6q 2837 1 A a DT cord-006870-f5w6fw6q 2837 2 total total NN cord-006870-f5w6fw6q 2837 3 of of IN cord-006870-f5w6fw6q 2837 4 112 112 CD cord-006870-f5w6fw6q 2837 5 patients patient NNS cord-006870-f5w6fw6q 2837 6 were be VBD cord-006870-f5w6fw6q 2837 7 enrolled enrol VBN cord-006870-f5w6fw6q 2837 8 over over IN cord-006870-f5w6fw6q 2837 9 4 4 CD cord-006870-f5w6fw6q 2837 10 months month NNS cord-006870-f5w6fw6q 2837 11 from from IN cord-006870-f5w6fw6q 2837 12 June June NNP cord-006870-f5w6fw6q 2837 13 to to IN cord-006870-f5w6fw6q 2837 14 September September NNP cord-006870-f5w6fw6q 2837 15 2016 2016 CD cord-006870-f5w6fw6q 2837 16 , , , cord-006870-f5w6fw6q 2837 17 11 11 CD cord-006870-f5w6fw6q 2837 18 of of IN cord-006870-f5w6fw6q 2837 19 which which WDT cord-006870-f5w6fw6q 2837 20 whom whom WP cord-006870-f5w6fw6q 2837 21 ( ( -LRB- cord-006870-f5w6fw6q 2837 22 9.8 9.8 CD cord-006870-f5w6fw6q 2837 23 % % NN cord-006870-f5w6fw6q 2837 24 ) ) -RRB- cord-006870-f5w6fw6q 2837 25 died die VBD cord-006870-f5w6fw6q 2837 26 within within IN cord-006870-f5w6fw6q 2837 27 30 30 CD cord-006870-f5w6fw6q 2837 28 days day NNS cord-006870-f5w6fw6q 2837 29 of of IN cord-006870-f5w6fw6q 2837 30 admission admission NN cord-006870-f5w6fw6q 2837 31 . . . cord-006870-f5w6fw6q 2838 1 There there EX cord-006870-f5w6fw6q 2838 2 were be VBD cord-006870-f5w6fw6q 2838 3 no no DT cord-006870-f5w6fw6q 2838 4 statistically statistically RB cord-006870-f5w6fw6q 2838 5 significant significant JJ cord-006870-f5w6fw6q 2838 6 differences difference NNS cord-006870-f5w6fw6q 2838 7 in in IN cord-006870-f5w6fw6q 2838 8 age age NN cord-006870-f5w6fw6q 2838 9 or or CC cord-006870-f5w6fw6q 2838 10 gender gender NN cord-006870-f5w6fw6q 2838 11 between between IN cord-006870-f5w6fw6q 2838 12 the the DT cord-006870-f5w6fw6q 2838 13 two two CD cord-006870-f5w6fw6q 2838 14 groups group NNS cord-006870-f5w6fw6q 2838 15 . . . cord-006870-f5w6fw6q 2839 1 The the DT cord-006870-f5w6fw6q 2839 2 30-day 30-day CD cord-006870-f5w6fw6q 2839 3 mortality mortality NN cord-006870-f5w6fw6q 2839 4 group group NN cord-006870-f5w6fw6q 2839 5 had have VBD cord-006870-f5w6fw6q 2839 6 a a DT cord-006870-f5w6fw6q 2839 7 higher high JJR cord-006870-f5w6fw6q 2839 8 mean mean NN cord-006870-f5w6fw6q 2839 9 Charlson Charlson NNP cord-006870-f5w6fw6q 2839 10 Comorbidity Comorbidity NNP cord-006870-f5w6fw6q 2839 11 Index Index NNP cord-006870-f5w6fw6q 2839 12 ( ( -LRB- cord-006870-f5w6fw6q 2839 13 CCI CCI NNP cord-006870-f5w6fw6q 2839 14 ) ) -RRB- cord-006870-f5w6fw6q 2839 15 ( ( -LRB- cord-006870-f5w6fw6q 2839 16 3.0 3.0 CD cord-006870-f5w6fw6q 2839 17 vs vs IN cord-006870-f5w6fw6q 2839 18 1.6 1.6 CD cord-006870-f5w6fw6q 2839 19 , , , cord-006870-f5w6fw6q 2839 20 p=0.027 p=0.027 RB cord-006870-f5w6fw6q 2839 21 ) ) -RRB- cord-006870-f5w6fw6q 2839 22 as as RB cord-006870-f5w6fw6q 2839 23 well well RB cord-006870-f5w6fw6q 2839 24 as as IN cord-006870-f5w6fw6q 2839 25 mean mean JJ cord-006870-f5w6fw6q 2839 26 NSE NSE NNP cord-006870-f5w6fw6q 2839 27 ( ( -LRB- cord-006870-f5w6fw6q 2839 28 39.1 39.1 CD cord-006870-f5w6fw6q 2839 29 vs vs IN cord-006870-f5w6fw6q 2839 30 13.9 13.9 CD cord-006870-f5w6fw6q 2839 31 ug ug NNP cord-006870-f5w6fw6q 2839 32 / / SYM cord-006870-f5w6fw6q 2839 33 L L NNP cord-006870-f5w6fw6q 2839 34 , , , cord-006870-f5w6fw6q 2839 35 p=0.008 p=0.008 NNP cord-006870-f5w6fw6q 2839 36 ) ) -RRB- cord-006870-f5w6fw6q 2839 37 and and CC cord-006870-f5w6fw6q 2839 38 BNP BNP NNP cord-006870-f5w6fw6q 2839 39 levels level NNS cord-006870-f5w6fw6q 2839 40 ( ( -LRB- cord-006870-f5w6fw6q 2839 41 590.2 590.2 CD cord-006870-f5w6fw6q 2839 42 vs vs IN cord-006870-f5w6fw6q 2839 43 177.3 177.3 CD cord-006870-f5w6fw6q 2839 44 pg pg NNP cord-006870-f5w6fw6q 2839 45 / / SYM cord-006870-f5w6fw6q 2839 46 mL mL NNP cord-006870-f5w6fw6q 2839 47 , , , cord-006870-f5w6fw6q 2839 48 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 2839 49 ) ) -RRB- cord-006870-f5w6fw6q 2839 50 . . . cord-006870-f5w6fw6q 2840 1 Mean mean JJ cord-006870-f5w6fw6q 2840 2 CRP CRP NNP cord-006870-f5w6fw6q 2840 3 , , , cord-006870-f5w6fw6q 2840 4 lactate lactate NN cord-006870-f5w6fw6q 2840 5 , , , cord-006870-f5w6fw6q 2840 6 and and CC cord-006870-f5w6fw6q 2840 7 LDH LDH NNP cord-006870-f5w6fw6q 2840 8 were be VBD cord-006870-f5w6fw6q 2840 9 also also RB cord-006870-f5w6fw6q 2840 10 higher high JJR cord-006870-f5w6fw6q 2840 11 in in IN cord-006870-f5w6fw6q 2840 12 the the DT cord-006870-f5w6fw6q 2840 13 30-day 30-day CD cord-006870-f5w6fw6q 2840 14 mortality mortality NN cord-006870-f5w6fw6q 2840 15 group group NN cord-006870-f5w6fw6q 2840 16 ( ( -LRB- cord-006870-f5w6fw6q 2840 17 79.5 79.5 CD cord-006870-f5w6fw6q 2840 18 vs vs IN cord-006870-f5w6fw6q 2840 19 51.8 51.8 CD cord-006870-f5w6fw6q 2840 20 mg mg NNP cord-006870-f5w6fw6q 2840 21 / / SYM cord-006870-f5w6fw6q 2840 22 L L NNP cord-006870-f5w6fw6q 2840 23 , , , cord-006870-f5w6fw6q 2840 24 2.3 2.3 CD cord-006870-f5w6fw6q 2840 25 vs vs IN cord-006870-f5w6fw6q 2840 26 1.9 1.9 CD cord-006870-f5w6fw6q 2840 27 mmol mmol JJ cord-006870-f5w6fw6q 2840 28 / / SYM cord-006870-f5w6fw6q 2840 29 L L NNP cord-006870-f5w6fw6q 2840 30 , , , cord-006870-f5w6fw6q 2840 31 and and CC cord-006870-f5w6fw6q 2840 32 307.2 307.2 CD cord-006870-f5w6fw6q 2840 33 vs vs IN cord-006870-f5w6fw6q 2840 34 274.2 274.2 CD cord-006870-f5w6fw6q 2840 35 U U NNP cord-006870-f5w6fw6q 2840 36 / / SYM cord-006870-f5w6fw6q 2840 37 L L NNP cord-006870-f5w6fw6q 2840 38 ) ) -RRB- cord-006870-f5w6fw6q 2840 39 while while IN cord-006870-f5w6fw6q 2840 40 mean mean JJ cord-006870-f5w6fw6q 2840 41 albumin albumin NN cord-006870-f5w6fw6q 2840 42 was be VBD cord-006870-f5w6fw6q 2840 43 lower low JJR cord-006870-f5w6fw6q 2840 44 ( ( -LRB- cord-006870-f5w6fw6q 2840 45 3.0 3.0 CD cord-006870-f5w6fw6q 2840 46 vs vs IN cord-006870-f5w6fw6q 2840 47 3.3 3.3 CD cord-006870-f5w6fw6q 2840 48 g g NN cord-006870-f5w6fw6q 2840 49 / / SYM cord-006870-f5w6fw6q 2840 50 dL dl NN cord-006870-f5w6fw6q 2840 51 ) ) -RRB- cord-006870-f5w6fw6q 2840 52 , , , cord-006870-f5w6fw6q 2840 53 although although IN cord-006870-f5w6fw6q 2840 54 these these DT cord-006870-f5w6fw6q 2840 55 differences difference NNS cord-006870-f5w6fw6q 2840 56 were be VBD cord-006870-f5w6fw6q 2840 57 not not RB cord-006870-f5w6fw6q 2840 58 statistically statistically RB cord-006870-f5w6fw6q 2840 59 significant significant JJ cord-006870-f5w6fw6q 2840 60 ( ( -LRB- cord-006870-f5w6fw6q 2840 61 p<0.35 p<0.35 ADD cord-006870-f5w6fw6q 2840 62 ) ) -RRB- cord-006870-f5w6fw6q 2840 63 . . . cord-006870-f5w6fw6q 2841 1 CCI CCI NNP cord-006870-f5w6fw6q 2841 2 and and CC cord-006870-f5w6fw6q 2841 3 serological serological JJ cord-006870-f5w6fw6q 2841 4 biomarkers biomarker NNS cord-006870-f5w6fw6q 2841 5 may may MD cord-006870-f5w6fw6q 2841 6 have have VB cord-006870-f5w6fw6q 2841 7 utility utility NN cord-006870-f5w6fw6q 2841 8 in in IN cord-006870-f5w6fw6q 2841 9 predicting predict VBG cord-006870-f5w6fw6q 2841 10 30-day 30-day CD cord-006870-f5w6fw6q 2841 11 mortality mortality NN cord-006870-f5w6fw6q 2841 12 among among IN cord-006870-f5w6fw6q 2841 13 patients patient NNS cord-006870-f5w6fw6q 2841 14 admitted admit VBN cord-006870-f5w6fw6q 2841 15 to to IN cord-006870-f5w6fw6q 2841 16 the the DT cord-006870-f5w6fw6q 2841 17 NCCU NCCU NNP cord-006870-f5w6fw6q 2841 18 . . . cord-006870-f5w6fw6q 2842 1 As as IN cord-006870-f5w6fw6q 2842 2 we -PRON- PRP cord-006870-f5w6fw6q 2842 3 continue continue VBP cord-006870-f5w6fw6q 2842 4 enrollment enrollment NN cord-006870-f5w6fw6q 2842 5 , , , cord-006870-f5w6fw6q 2842 6 we -PRON- PRP cord-006870-f5w6fw6q 2842 7 plan plan VBP cord-006870-f5w6fw6q 2842 8 to to TO cord-006870-f5w6fw6q 2842 9 develop develop VB cord-006870-f5w6fw6q 2842 10 a a DT cord-006870-f5w6fw6q 2842 11 predictive predictive JJ cord-006870-f5w6fw6q 2842 12 model model NN cord-006870-f5w6fw6q 2842 13 for for IN cord-006870-f5w6fw6q 2842 14 30-day 30-day CD cord-006870-f5w6fw6q 2842 15 mortality mortality NN cord-006870-f5w6fw6q 2842 16 on on IN cord-006870-f5w6fw6q 2842 17 admission admission NN cord-006870-f5w6fw6q 2842 18 for for IN cord-006870-f5w6fw6q 2842 19 patients patient NNS cord-006870-f5w6fw6q 2842 20 admitted admit VBN cord-006870-f5w6fw6q 2842 21 to to IN cord-006870-f5w6fw6q 2842 22 the the DT cord-006870-f5w6fw6q 2842 23 NCCU NCCU NNP cord-006870-f5w6fw6q 2842 24 using use VBG cord-006870-f5w6fw6q 2842 25 serological serological JJ cord-006870-f5w6fw6q 2842 26 biomarkers biomarker NNS cord-006870-f5w6fw6q 2842 27 , , , cord-006870-f5w6fw6q 2842 28 CCI CCI NNP cord-006870-f5w6fw6q 2842 29 and and CC cord-006870-f5w6fw6q 2842 30 admission admission NN cord-006870-f5w6fw6q 2842 31 characteristics characteristic NNS cord-006870-f5w6fw6q 2842 32 . . . cord-006870-f5w6fw6q 2843 1 Among among IN cord-006870-f5w6fw6q 2843 2 hospitalized hospitalize VBN cord-006870-f5w6fw6q 2843 3 acutely acutely RB cord-006870-f5w6fw6q 2843 4 ill ill JJ cord-006870-f5w6fw6q 2843 5 medical medical JJ cord-006870-f5w6fw6q 2843 6 patients patient NNS cord-006870-f5w6fw6q 2843 7 , , , cord-006870-f5w6fw6q 2843 8 the the DT cord-006870-f5w6fw6q 2843 9 risk risk NN cord-006870-f5w6fw6q 2843 10 for for IN cord-006870-f5w6fw6q 2843 11 venous venous JJ cord-006870-f5w6fw6q 2843 12 thromboembolism thromboembolism NN cord-006870-f5w6fw6q 2843 13 ( ( -LRB- cord-006870-f5w6fw6q 2843 14 VTE VTE NNP cord-006870-f5w6fw6q 2843 15 ) ) -RRB- cord-006870-f5w6fw6q 2843 16 is be VBZ cord-006870-f5w6fw6q 2843 17 high high JJ cord-006870-f5w6fw6q 2843 18 . . . cord-006870-f5w6fw6q 2844 1 The the DT cord-006870-f5w6fw6q 2844 2 goal goal NN cord-006870-f5w6fw6q 2844 3 was be VBD cord-006870-f5w6fw6q 2844 4 to to TO cord-006870-f5w6fw6q 2844 5 examine examine VB cord-006870-f5w6fw6q 2844 6 VTE VTE NNP cord-006870-f5w6fw6q 2844 7 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2844 8 of of IN cord-006870-f5w6fw6q 2844 9 at at IN cord-006870-f5w6fw6q 2844 10 - - HYPH cord-006870-f5w6fw6q 2844 11 risk risk NN cord-006870-f5w6fw6q 2844 12 patients patient NNS cord-006870-f5w6fw6q 2844 13 and and CC cord-006870-f5w6fw6q 2844 14 VTE VTE NNP cord-006870-f5w6fw6q 2844 15 risk risk NN cord-006870-f5w6fw6q 2844 16 during during IN cord-006870-f5w6fw6q 2844 17 hospitalization hospitalization NN cord-006870-f5w6fw6q 2844 18 and and CC cord-006870-f5w6fw6q 2844 19 in in IN cord-006870-f5w6fw6q 2844 20 the the DT cord-006870-f5w6fw6q 2844 21 outpatient outpatient NN cord-006870-f5w6fw6q 2844 22 continuum continuum NN cord-006870-f5w6fw6q 2844 23 of of IN cord-006870-f5w6fw6q 2844 24 care care NN cord-006870-f5w6fw6q 2844 25 . . . cord-006870-f5w6fw6q 2845 1 Acutely acutely RB cord-006870-f5w6fw6q 2845 2 ill ill JJ cord-006870-f5w6fw6q 2845 3 medical medical JJ cord-006870-f5w6fw6q 2845 4 patients patient NNS cord-006870-f5w6fw6q 2845 5 were be VBD cord-006870-f5w6fw6q 2845 6 identified identify VBN cord-006870-f5w6fw6q 2845 7 from from IN cord-006870-f5w6fw6q 2845 8 the the DT cord-006870-f5w6fw6q 2845 9 MarketScan MarketScan NNP cord-006870-f5w6fw6q 2845 10 Commercial Commercial NNP cord-006870-f5w6fw6q 2845 11 and and CC cord-006870-f5w6fw6q 2845 12 Medicare Medicare NNP cord-006870-f5w6fw6q 2845 13 databases database NNS cord-006870-f5w6fw6q 2845 14 from from IN cord-006870-f5w6fw6q 2845 15 1/1/2012 1/1/2012 CD cord-006870-f5w6fw6q 2845 16 to to IN cord-006870-f5w6fw6q 2845 17 6/30/2015 6/30/2015 CD cord-006870-f5w6fw6q 2845 18 . . . cord-006870-f5w6fw6q 2846 1 Inclusion inclusion NN cord-006870-f5w6fw6q 2846 2 criteria criterion NNS cord-006870-f5w6fw6q 2846 3 were be VBD cord-006870-f5w6fw6q 2846 4 hospitalization hospitalization NN cord-006870-f5w6fw6q 2846 5 for for IN cord-006870-f5w6fw6q 2846 6 heart heart NN cord-006870-f5w6fw6q 2846 7 failure failure NN cord-006870-f5w6fw6q 2846 8 , , , cord-006870-f5w6fw6q 2846 9 respiratory respiratory JJ cord-006870-f5w6fw6q 2846 10 diseases disease NNS cord-006870-f5w6fw6q 2846 11 , , , cord-006870-f5w6fw6q 2846 12 ischemic ischemic JJ cord-006870-f5w6fw6q 2846 13 stroke stroke NN cord-006870-f5w6fw6q 2846 14 , , , cord-006870-f5w6fw6q 2846 15 cancer cancer NN cord-006870-f5w6fw6q 2846 16 , , , cord-006870-f5w6fw6q 2846 17 infectious infectious JJ cord-006870-f5w6fw6q 2846 18 diseases disease NNS cord-006870-f5w6fw6q 2846 19 , , , cord-006870-f5w6fw6q 2846 20 and and CC cord-006870-f5w6fw6q 2846 21 rheumatic rheumatic JJ cord-006870-f5w6fw6q 2846 22 diseases disease NNS cord-006870-f5w6fw6q 2846 23 ; ; : cord-006870-f5w6fw6q 2846 24 6 6 CD cord-006870-f5w6fw6q 2846 25 months month NNS cord-006870-f5w6fw6q 2846 26 of of IN cord-006870-f5w6fw6q 2846 27 continuous continuous JJ cord-006870-f5w6fw6q 2846 28 insurance insurance NN cord-006870-f5w6fw6q 2846 29 coverage coverage NN cord-006870-f5w6fw6q 2846 30 prior prior RB cord-006870-f5w6fw6q 2846 31 to to IN cord-006870-f5w6fw6q 2846 32 ( ( -LRB- cord-006870-f5w6fw6q 2846 33 baseline baseline JJ cord-006870-f5w6fw6q 2846 34 period period NN cord-006870-f5w6fw6q 2846 35 ) ) -RRB- cord-006870-f5w6fw6q 2846 36 and and CC cord-006870-f5w6fw6q 2846 37 after after IN cord-006870-f5w6fw6q 2846 38 ( ( -LRB- cord-006870-f5w6fw6q 2846 39 follow follow NN cord-006870-f5w6fw6q 2846 40 - - HYPH cord-006870-f5w6fw6q 2846 41 up up NN cord-006870-f5w6fw6q 2846 42 period period NN cord-006870-f5w6fw6q 2846 43 ) ) -RRB- cord-006870-f5w6fw6q 2846 44 the the DT cord-006870-f5w6fw6q 2846 45 index index NN cord-006870-f5w6fw6q 2846 46 hospitalization hospitalization NN cord-006870-f5w6fw6q 2846 47 . . . cord-006870-f5w6fw6q 2847 1 Outcomes outcome NNS cord-006870-f5w6fw6q 2847 2 included include VBD cord-006870-f5w6fw6q 2847 3 the the DT cord-006870-f5w6fw6q 2847 4 proportions proportion NNS cord-006870-f5w6fw6q 2847 5 of of IN cord-006870-f5w6fw6q 2847 6 patients patient NNS cord-006870-f5w6fw6q 2847 7 receiving receive VBG cord-006870-f5w6fw6q 2847 8 inpatient inpatient JJ cord-006870-f5w6fw6q 2847 9 and/or and/or CC cord-006870-f5w6fw6q 2847 10 outpatient outpatient JJ cord-006870-f5w6fw6q 2847 11 VTE VTE NNP cord-006870-f5w6fw6q 2847 12 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2847 13 , , , cord-006870-f5w6fw6q 2847 14 and and CC cord-006870-f5w6fw6q 2847 15 the the DT cord-006870-f5w6fw6q 2847 16 risk risk NN cord-006870-f5w6fw6q 2847 17 for for IN cord-006870-f5w6fw6q 2847 18 VTE VTE NNP cord-006870-f5w6fw6q 2847 19 events event NNS cord-006870-f5w6fw6q 2847 20 . . . cord-006870-f5w6fw6q 2848 1 years year NNS cord-006870-f5w6fw6q 2848 2 , , , cord-006870-f5w6fw6q 2848 3 and and CC cord-006870-f5w6fw6q 2848 4 55.4 55.4 CD cord-006870-f5w6fw6q 2848 5 % % NN cord-006870-f5w6fw6q 2848 6 were be VBD cord-006870-f5w6fw6q 2848 7 female female JJ cord-006870-f5w6fw6q 2848 8 . . . cord-006870-f5w6fw6q 2849 1 Patients patient NNS cord-006870-f5w6fw6q 2849 2 were be VBD cord-006870-f5w6fw6q 2849 3 hospitalized hospitalize VBN cord-006870-f5w6fw6q 2849 4 for for IN cord-006870-f5w6fw6q 2849 5 infectious infectious JJ cord-006870-f5w6fw6q 2849 6 diseases disease NNS cord-006870-f5w6fw6q 2849 7 ( ( -LRB- cord-006870-f5w6fw6q 2849 8 40.6 40.6 CD cord-006870-f5w6fw6q 2849 9 % % NN cord-006870-f5w6fw6q 2849 10 ) ) -RRB- cord-006870-f5w6fw6q 2849 11 , , , cord-006870-f5w6fw6q 2849 12 respiratory respiratory JJ cord-006870-f5w6fw6q 2849 13 diseases disease NNS cord-006870-f5w6fw6q 2849 14 ( ( -LRB- cord-006870-f5w6fw6q 2849 15 31.0 31.0 CD cord-006870-f5w6fw6q 2849 16 % % NN cord-006870-f5w6fw6q 2849 17 ) ) -RRB- cord-006870-f5w6fw6q 2849 18 , , , cord-006870-f5w6fw6q 2849 19 cancer cancer NN cord-006870-f5w6fw6q 2849 20 ( ( -LRB- cord-006870-f5w6fw6q 2849 21 10.7 10.7 CD cord-006870-f5w6fw6q 2849 22 % % NN cord-006870-f5w6fw6q 2849 23 ) ) -RRB- cord-006870-f5w6fw6q 2849 24 , , , cord-006870-f5w6fw6q 2849 25 heart heart NN cord-006870-f5w6fw6q 2849 26 failure failure NN cord-006870-f5w6fw6q 2849 27 ( ( -LRB- cord-006870-f5w6fw6q 2849 28 10.4 10.4 CD cord-006870-f5w6fw6q 2849 29 % % NN cord-006870-f5w6fw6q 2849 30 ) ) -RRB- cord-006870-f5w6fw6q 2849 31 , , , cord-006870-f5w6fw6q 2849 32 ischemic ischemic JJ cord-006870-f5w6fw6q 2849 33 stroke stroke NN cord-006870-f5w6fw6q 2849 34 ( ( -LRB- cord-006870-f5w6fw6q 2849 35 6.4 6.4 CD cord-006870-f5w6fw6q 2849 36 % % NN cord-006870-f5w6fw6q 2849 37 ) ) -RRB- cord-006870-f5w6fw6q 2849 38 , , , cord-006870-f5w6fw6q 2849 39 and and CC cord-006870-f5w6fw6q 2849 40 rheumatic rheumatic JJ cord-006870-f5w6fw6q 2849 41 diseases disease NNS cord-006870-f5w6fw6q 2849 42 ( ( -LRB- cord-006870-f5w6fw6q 2849 43 0.9 0.9 CD cord-006870-f5w6fw6q 2849 44 % % NN cord-006870-f5w6fw6q 2849 45 ) ) -RRB- cord-006870-f5w6fw6q 2849 46 . . . cord-006870-f5w6fw6q 2850 1 Mean mean JJ cord-006870-f5w6fw6q 2850 2 hospital hospital NN cord-006870-f5w6fw6q 2850 3 length length NN cord-006870-f5w6fw6q 2850 4 of of IN cord-006870-f5w6fw6q 2850 5 stay stay NN cord-006870-f5w6fw6q 2850 6 was be VBD cord-006870-f5w6fw6q 2850 7 4.8 4.8 CD cord-006870-f5w6fw6q 2850 8 days day NNS cord-006870-f5w6fw6q 2850 9 . . . cord-006870-f5w6fw6q 2851 1 In in IN cord-006870-f5w6fw6q 2851 2 total total JJ cord-006870-f5w6fw6q 2851 3 , , , cord-006870-f5w6fw6q 2851 4 59.1 59.1 CD cord-006870-f5w6fw6q 2851 5 % % NN cord-006870-f5w6fw6q 2851 6 ( ( -LRB- cord-006870-f5w6fw6q 2851 7 n=10,581 n=10,581 NNP cord-006870-f5w6fw6q 2851 8 ) ) -RRB- cord-006870-f5w6fw6q 2851 9 of of IN cord-006870-f5w6fw6q 2851 10 patients patient NNS cord-006870-f5w6fw6q 2851 11 did do VBD cord-006870-f5w6fw6q 2851 12 not not RB cord-006870-f5w6fw6q 2851 13 receive receive VB cord-006870-f5w6fw6q 2851 14 any any DT cord-006870-f5w6fw6q 2851 15 VTE VTE NNP cord-006870-f5w6fw6q 2851 16 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2851 17 , , , cord-006870-f5w6fw6q 2851 18 and and CC cord-006870-f5w6fw6q 2851 19 7.1 7.1 CD cord-006870-f5w6fw6q 2851 20 % % NN cord-006870-f5w6fw6q 2851 21 ( ( -LRB- cord-006870-f5w6fw6q 2851 22 n=1,267 n=1,267 NNP cord-006870-f5w6fw6q 2851 23 ) ) -RRB- cord-006870-f5w6fw6q 2851 24 received receive VBD cord-006870-f5w6fw6q 2851 25 both both CC cord-006870-f5w6fw6q 2851 26 inpatient inpatient JJ cord-006870-f5w6fw6q 2851 27 and and CC cord-006870-f5w6fw6q 2851 28 outpatient outpatient JJ cord-006870-f5w6fw6q 2851 29 VTE VTE NNP cord-006870-f5w6fw6q 2851 30 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2851 31 . . . cord-006870-f5w6fw6q 2852 1 During during IN cord-006870-f5w6fw6q 2852 2 hospitalization hospitalization NN cord-006870-f5w6fw6q 2852 3 , , , cord-006870-f5w6fw6q 2852 4 38.2 38.2 CD cord-006870-f5w6fw6q 2852 5 % % NN cord-006870-f5w6fw6q 2852 6 ( ( -LRB- cord-006870-f5w6fw6q 2852 7 n=6,843 n=6,843 NNP cord-006870-f5w6fw6q 2852 8 ) ) -RRB- cord-006870-f5w6fw6q 2852 9 received receive VBD cord-006870-f5w6fw6q 2852 10 VTE VTE NNP cord-006870-f5w6fw6q 2852 11 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2852 12 ( ( -LRB- cord-006870-f5w6fw6q 2852 13 enoxaparin enoxaparin NNP cord-006870-f5w6fw6q 2852 14 , , , cord-006870-f5w6fw6q 2852 15 76.7 76.7 CD cord-006870-f5w6fw6q 2852 16 % % NN cord-006870-f5w6fw6q 2852 17 ; ; , cord-006870-f5w6fw6q 2852 18 warfarin warfarin NN cord-006870-f5w6fw6q 2852 19 , , , cord-006870-f5w6fw6q 2852 20 15.2 15.2 CD cord-006870-f5w6fw6q 2852 21 % % NN cord-006870-f5w6fw6q 2852 22 ; ; : cord-006870-f5w6fw6q 2852 23 enoxaparin enoxaparin NNP cord-006870-f5w6fw6q 2852 24 and and CC cord-006870-f5w6fw6q 2852 25 warfarin warfarin NN cord-006870-f5w6fw6q 2852 26 , , , cord-006870-f5w6fw6q 2852 27 5.3 5.3 CD cord-006870-f5w6fw6q 2852 28 % % NN cord-006870-f5w6fw6q 2852 29 ; ; , cord-006870-f5w6fw6q 2852 30 a a DT cord-006870-f5w6fw6q 2852 31 direct direct JJ cord-006870-f5w6fw6q 2852 32 oral oral JJ cord-006870-f5w6fw6q 2852 33 anticoagulant anticoagulant NN cord-006870-f5w6fw6q 2852 34 ( ( -LRB- cord-006870-f5w6fw6q 2852 35 DOAC DOAC NNP cord-006870-f5w6fw6q 2852 36 ) ) -RRB- cord-006870-f5w6fw6q 2852 37 , , , cord-006870-f5w6fw6q 2852 38 ~2 ~2 CD cord-006870-f5w6fw6q 2852 39 % % NN cord-006870-f5w6fw6q 2852 40 ) ) -RRB- cord-006870-f5w6fw6q 2852 41 . . . cord-006870-f5w6fw6q 2853 1 Following follow VBG cord-006870-f5w6fw6q 2853 2 discharge discharge NN cord-006870-f5w6fw6q 2853 3 , , , cord-006870-f5w6fw6q 2853 4 9.7 9.7 CD cord-006870-f5w6fw6q 2853 5 % % NN cord-006870-f5w6fw6q 2853 6 ( ( -LRB- cord-006870-f5w6fw6q 2853 7 n=1,738 n=1,738 NNP cord-006870-f5w6fw6q 2853 8 ) ) -RRB- cord-006870-f5w6fw6q 2853 9 received receive VBN cord-006870-f5w6fw6q 2853 10 outpatient outpatient NN cord-006870-f5w6fw6q 2853 11 VTE VTE NNP cord-006870-f5w6fw6q 2853 12 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2853 13 ( ( -LRB- cord-006870-f5w6fw6q 2853 14 warfarin warfarin NN cord-006870-f5w6fw6q 2853 15 , , , cord-006870-f5w6fw6q 2853 16 43.8 43.8 CD cord-006870-f5w6fw6q 2853 17 % % NN cord-006870-f5w6fw6q 2853 18 ; ; : cord-006870-f5w6fw6q 2853 19 DOAC DOAC NNP cord-006870-f5w6fw6q 2853 20 , , , cord-006870-f5w6fw6q 2853 21 13.7 13.7 CD cord-006870-f5w6fw6q 2853 22 % % NN cord-006870-f5w6fw6q 2853 23 ; ; : cord-006870-f5w6fw6q 2853 24 enoxaparin enoxaparin NNP cord-006870-f5w6fw6q 2853 25 , , , cord-006870-f5w6fw6q 2853 26 10.1 10.1 CD cord-006870-f5w6fw6q 2853 27 % % NN cord-006870-f5w6fw6q 2853 28 ; ; : cord-006870-f5w6fw6q 2853 29 enoxaparin enoxaparin NNP cord-006870-f5w6fw6q 2853 30 and and CC cord-006870-f5w6fw6q 2853 31 warfarin warfarin NN cord-006870-f5w6fw6q 2853 32 , , , cord-006870-f5w6fw6q 2853 33 7.6 7.6 CD cord-006870-f5w6fw6q 2853 34 % % NN cord-006870-f5w6fw6q 2853 35 ) ) -RRB- cord-006870-f5w6fw6q 2853 36 . . . cord-006870-f5w6fw6q 2854 1 Among among IN cord-006870-f5w6fw6q 2854 2 the the DT cord-006870-f5w6fw6q 2854 3 entire entire JJ cord-006870-f5w6fw6q 2854 4 study study NN cord-006870-f5w6fw6q 2854 5 population population NN cord-006870-f5w6fw6q 2854 6 , , , cord-006870-f5w6fw6q 2854 7 the the DT cord-006870-f5w6fw6q 2854 8 VTE VTE NNP cord-006870-f5w6fw6q 2854 9 event event NN cord-006870-f5w6fw6q 2854 10 risk risk NN cord-006870-f5w6fw6q 2854 11 remained remain VBD cord-006870-f5w6fw6q 2854 12 elevated elevated JJ cord-006870-f5w6fw6q 2854 13 up up RP cord-006870-f5w6fw6q 2854 14 to to TO cord-006870-f5w6fw6q 2854 15 30 30 CD cord-006870-f5w6fw6q 2854 16 - - SYM cord-006870-f5w6fw6q 2854 17 40 40 CD cord-006870-f5w6fw6q 2854 18 days day NNS cord-006870-f5w6fw6q 2854 19 after after IN cord-006870-f5w6fw6q 2854 20 hospital hospital NN cord-006870-f5w6fw6q 2854 21 admission admission NN cord-006870-f5w6fw6q 2854 22 . . . cord-006870-f5w6fw6q 2855 1 Among among IN cord-006870-f5w6fw6q 2855 2 hospitalized hospitalize VBN cord-006870-f5w6fw6q 2855 3 acutely acutely RB cord-006870-f5w6fw6q 2855 4 ill ill JJ cord-006870-f5w6fw6q 2855 5 medical medical JJ cord-006870-f5w6fw6q 2855 6 patients patient NNS cord-006870-f5w6fw6q 2855 7 , , , cord-006870-f5w6fw6q 2855 8 the the DT cord-006870-f5w6fw6q 2855 9 risk risk NN cord-006870-f5w6fw6q 2855 10 for for IN cord-006870-f5w6fw6q 2855 11 VTE VTE NNP cord-006870-f5w6fw6q 2855 12 was be VBD cord-006870-f5w6fw6q 2855 13 present present JJ cord-006870-f5w6fw6q 2855 14 in in IN cord-006870-f5w6fw6q 2855 15 both both CC cord-006870-f5w6fw6q 2855 16 the the DT cord-006870-f5w6fw6q 2855 17 inpatient inpatient JJ cord-006870-f5w6fw6q 2855 18 and and CC cord-006870-f5w6fw6q 2855 19 outpatient outpatient NN cord-006870-f5w6fw6q 2855 20 settings setting NNS cord-006870-f5w6fw6q 2855 21 , , , cord-006870-f5w6fw6q 2855 22 with with IN cord-006870-f5w6fw6q 2855 23 significant significant JJ cord-006870-f5w6fw6q 2855 24 VTE VTE NNP cord-006870-f5w6fw6q 2855 25 risk risk NN cord-006870-f5w6fw6q 2855 26 extending extend VBG cord-006870-f5w6fw6q 2855 27 into into IN cord-006870-f5w6fw6q 2855 28 the the DT cord-006870-f5w6fw6q 2855 29 post post JJ cord-006870-f5w6fw6q 2855 30 - - JJ cord-006870-f5w6fw6q 2855 31 hospitalization hospitalization JJ cord-006870-f5w6fw6q 2855 32 period period NN cord-006870-f5w6fw6q 2855 33 . . . cord-006870-f5w6fw6q 2856 1 Only only RB cord-006870-f5w6fw6q 2856 2 a a DT cord-006870-f5w6fw6q 2856 3 small small JJ cord-006870-f5w6fw6q 2856 4 portion portion NN cord-006870-f5w6fw6q 2856 5 of of IN cord-006870-f5w6fw6q 2856 6 at at IN cord-006870-f5w6fw6q 2856 7 - - HYPH cord-006870-f5w6fw6q 2856 8 risk risk NN cord-006870-f5w6fw6q 2856 9 patients patient NNS cord-006870-f5w6fw6q 2856 10 ( ( -LRB- cord-006870-f5w6fw6q 2856 11 7.1 7.1 CD cord-006870-f5w6fw6q 2856 12 % % NN cord-006870-f5w6fw6q 2856 13 ) ) -RRB- cord-006870-f5w6fw6q 2856 14 received receive VBD cord-006870-f5w6fw6q 2856 15 VTE VTE NNP cord-006870-f5w6fw6q 2856 16 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2856 17 in in IN cord-006870-f5w6fw6q 2856 18 both both CC cord-006870-f5w6fw6q 2856 19 the the DT cord-006870-f5w6fw6q 2856 20 inpatient inpatient JJ cord-006870-f5w6fw6q 2856 21 and and CC cord-006870-f5w6fw6q 2856 22 outpatient outpatient JJ cord-006870-f5w6fw6q 2856 23 continuum continuum NN cord-006870-f5w6fw6q 2856 24 of of IN cord-006870-f5w6fw6q 2856 25 care care NN cord-006870-f5w6fw6q 2856 26 , , , cord-006870-f5w6fw6q 2856 27 suggesting suggest VBG cord-006870-f5w6fw6q 2856 28 an an DT cord-006870-f5w6fw6q 2856 29 unmet unmet JJ cord-006870-f5w6fw6q 2856 30 medical medical JJ cord-006870-f5w6fw6q 2856 31 need need NN cord-006870-f5w6fw6q 2856 32 for for IN cord-006870-f5w6fw6q 2856 33 VTE VTE NNP cord-006870-f5w6fw6q 2856 34 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 2856 35 in in IN cord-006870-f5w6fw6q 2856 36 the the DT cord-006870-f5w6fw6q 2856 37 post post NN cord-006870-f5w6fw6q 2856 38 - - JJ cord-006870-f5w6fw6q 2856 39 hospitalization hospitalization NN cord-006870-f5w6fw6q 2856 40 . . . cord-006870-f5w6fw6q 2857 1 Brain brain NN cord-006870-f5w6fw6q 2857 2 edema edema NN cord-006870-f5w6fw6q 2857 3 is be VBZ cord-006870-f5w6fw6q 2857 4 a a DT cord-006870-f5w6fw6q 2857 5 good good JJ cord-006870-f5w6fw6q 2857 6 research research NN cord-006870-f5w6fw6q 2857 7 target target NN cord-006870-f5w6fw6q 2857 8 in in IN cord-006870-f5w6fw6q 2857 9 various various JJ cord-006870-f5w6fw6q 2857 10 forms form NNS cord-006870-f5w6fw6q 2857 11 of of IN cord-006870-f5w6fw6q 2857 12 neurologic neurologic JJ cord-006870-f5w6fw6q 2857 13 injury injury NN cord-006870-f5w6fw6q 2857 14 . . . cord-006870-f5w6fw6q 2858 1 A a DT cord-006870-f5w6fw6q 2858 2 real real JJ cord-006870-f5w6fw6q 2858 3 time time NN cord-006870-f5w6fw6q 2858 4 measurement measurement NN cord-006870-f5w6fw6q 2858 5 of of IN cord-006870-f5w6fw6q 2858 6 brain brain NN cord-006870-f5w6fw6q 2858 7 edema edema NN cord-006870-f5w6fw6q 2858 8 is be VBZ cord-006870-f5w6fw6q 2858 9 possible possible JJ cord-006870-f5w6fw6q 2858 10 using use VBG cord-006870-f5w6fw6q 2858 11 thermal thermal JJ cord-006870-f5w6fw6q 2858 12 conductivity conductivity NN cord-006870-f5w6fw6q 2858 13 methods method NNS cord-006870-f5w6fw6q 2858 14 . . . cord-006870-f5w6fw6q 2859 1 However however RB cord-006870-f5w6fw6q 2859 2 , , , cord-006870-f5w6fw6q 2859 3 this this DT cord-006870-f5w6fw6q 2859 4 technique technique NN cord-006870-f5w6fw6q 2859 5 might may MD cord-006870-f5w6fw6q 2859 6 be be VB cord-006870-f5w6fw6q 2859 7 hard hard JJ cord-006870-f5w6fw6q 2859 8 to to TO cord-006870-f5w6fw6q 2859 9 apply apply VB cord-006870-f5w6fw6q 2859 10 in in IN cord-006870-f5w6fw6q 2859 11 small small JJ cord-006870-f5w6fw6q 2859 12 rodents rodent NNS cord-006870-f5w6fw6q 2859 13 , , , cord-006870-f5w6fw6q 2859 14 which which WDT cord-006870-f5w6fw6q 2859 15 are be VBP cord-006870-f5w6fw6q 2859 16 commonly commonly RB cord-006870-f5w6fw6q 2859 17 used use VBN cord-006870-f5w6fw6q 2859 18 as as IN cord-006870-f5w6fw6q 2859 19 experimental experimental JJ cord-006870-f5w6fw6q 2859 20 brain brain NN cord-006870-f5w6fw6q 2859 21 edema edema NN cord-006870-f5w6fw6q 2859 22 models model NNS cord-006870-f5w6fw6q 2859 23 . . . cord-006870-f5w6fw6q 2860 1 We -PRON- PRP cord-006870-f5w6fw6q 2860 2 developed develop VBD cord-006870-f5w6fw6q 2860 3 a a DT cord-006870-f5w6fw6q 2860 4 new new JJ cord-006870-f5w6fw6q 2860 5 approach approach NN cord-006870-f5w6fw6q 2860 6 method method NN cord-006870-f5w6fw6q 2860 7 for for IN cord-006870-f5w6fw6q 2860 8 applying apply VBG cord-006870-f5w6fw6q 2860 9 thermal thermal JJ cord-006870-f5w6fw6q 2860 10 conductivity conductivity NN cord-006870-f5w6fw6q 2860 11 methods method NNS cord-006870-f5w6fw6q 2860 12 in in IN cord-006870-f5w6fw6q 2860 13 rodent rodent NN cord-006870-f5w6fw6q 2860 14 brain brain NN cord-006870-f5w6fw6q 2860 15 edema edema NN cord-006870-f5w6fw6q 2860 16 model model NN cord-006870-f5w6fw6q 2860 17 . . . cord-006870-f5w6fw6q 2861 1 A a DT cord-006870-f5w6fw6q 2861 2 10-week 10-week JJ cord-006870-f5w6fw6q 2861 3 - - HYPH cord-006870-f5w6fw6q 2861 4 old old JJ cord-006870-f5w6fw6q 2861 5 Spraque Spraque NNP cord-006870-f5w6fw6q 2861 6 - - HYPH cord-006870-f5w6fw6q 2861 7 Dawley Dawley NNP cord-006870-f5w6fw6q 2861 8 rats rat NNS cord-006870-f5w6fw6q 2861 9 were be VBD cord-006870-f5w6fw6q 2861 10 used use VBN cord-006870-f5w6fw6q 2861 11 for for IN cord-006870-f5w6fw6q 2861 12 brain brain NN cord-006870-f5w6fw6q 2861 13 edema edema NN cord-006870-f5w6fw6q 2861 14 model model NN cord-006870-f5w6fw6q 2861 15 . . . cord-006870-f5w6fw6q 2862 1 Qflow Qflow NNP cord-006870-f5w6fw6q 2862 2 500 500 CD cord-006870-f5w6fw6q 2862 3 probe probe NN cord-006870-f5w6fw6q 2862 4 was be VBD cord-006870-f5w6fw6q 2862 5 inserted insert VBN cord-006870-f5w6fw6q 2862 6 through through IN cord-006870-f5w6fw6q 2862 7 a a DT cord-006870-f5w6fw6q 2862 8 suboccipital suboccipital JJ cord-006870-f5w6fw6q 2862 9 burr burr NNP cord-006870-f5w6fw6q 2862 10 hole hole NN cord-006870-f5w6fw6q 2862 11 , , , cord-006870-f5w6fw6q 2862 12 located locate VBN cord-006870-f5w6fw6q 2862 13 3 3 CD cord-006870-f5w6fw6q 2862 14 mm mm NN cord-006870-f5w6fw6q 2862 15 left leave VBN cord-006870-f5w6fw6q 2862 16 from from IN cord-006870-f5w6fw6q 2862 17 the the DT cord-006870-f5w6fw6q 2862 18 midline midline NN cord-006870-f5w6fw6q 2862 19 , , , cord-006870-f5w6fw6q 2862 20 then then RB cord-006870-f5w6fw6q 2862 21 was be VBD cord-006870-f5w6fw6q 2862 22 advanced advance VBN cord-006870-f5w6fw6q 2862 23 anteriorly anteriorly RB cord-006870-f5w6fw6q 2862 24 10 10 CD cord-006870-f5w6fw6q 2862 25 mm mm NNS cord-006870-f5w6fw6q 2862 26 from from IN cord-006870-f5w6fw6q 2862 27 the the DT cord-006870-f5w6fw6q 2862 28 occipital occipital NNP cord-006870-f5w6fw6q 2862 29 bone bone NNP cord-006870-f5w6fw6q 2862 30 margin margin NN cord-006870-f5w6fw6q 2862 31 until until IN cord-006870-f5w6fw6q 2862 32 probe probe NN cord-006870-f5w6fw6q 2862 33 place place NN cord-006870-f5w6fw6q 2862 34 assistance assistance NN cord-006870-f5w6fw6q 2862 35 value value NN cord-006870-f5w6fw6q 2862 36 indicates indicate VBZ cord-006870-f5w6fw6q 2862 37 valid valid JJ cord-006870-f5w6fw6q 2862 38 values value NNS cord-006870-f5w6fw6q 2862 39 ( ( -LRB- cord-006870-f5w6fw6q 2862 40 ranging range VBG cord-006870-f5w6fw6q 2862 41 from from IN cord-006870-f5w6fw6q 2862 42 0 0 CD cord-006870-f5w6fw6q 2862 43 to to IN cord-006870-f5w6fw6q 2862 44 2.0 2.0 CD cord-006870-f5w6fw6q 2862 45 ) ) -RRB- cord-006870-f5w6fw6q 2862 46 . . . cord-006870-f5w6fw6q 2863 1 Probe Probe NNP cord-006870-f5w6fw6q 2863 2 was be VBD cord-006870-f5w6fw6q 2863 3 fixated fixate VBN cord-006870-f5w6fw6q 2863 4 using use VBG cord-006870-f5w6fw6q 2863 5 adhesive adhesive JJ cord-006870-f5w6fw6q 2863 6 glues glue NNS cord-006870-f5w6fw6q 2863 7 and and CC cord-006870-f5w6fw6q 2863 8 tagging tag VBG cord-006870-f5w6fw6q 2863 9 suture suture NN cord-006870-f5w6fw6q 2863 10 . . . cord-006870-f5w6fw6q 2864 1 In in IN cord-006870-f5w6fw6q 2864 2 vivo vivo NN cord-006870-f5w6fw6q 2864 3 brain brain NN cord-006870-f5w6fw6q 2864 4 water water NN cord-006870-f5w6fw6q 2864 5 content content NN cord-006870-f5w6fw6q 2864 6 was be VBD cord-006870-f5w6fw6q 2864 7 continuously continuously RB cord-006870-f5w6fw6q 2864 8 calculated calculate VBN cord-006870-f5w6fw6q 2864 9 using use VBG cord-006870-f5w6fw6q 2864 10 thermal thermal JJ cord-006870-f5w6fw6q 2864 11 conductivity conductivity NN cord-006870-f5w6fw6q 2864 12 values value NNS cord-006870-f5w6fw6q 2864 13 . . . cord-006870-f5w6fw6q 2865 1 For for IN cord-006870-f5w6fw6q 2865 2 validation validation NN cord-006870-f5w6fw6q 2865 3 , , , cord-006870-f5w6fw6q 2865 4 calculated calculate VBN cord-006870-f5w6fw6q 2865 5 brain brain NN cord-006870-f5w6fw6q 2865 6 edema edema NN cord-006870-f5w6fw6q 2865 7 was be VBD cord-006870-f5w6fw6q 2865 8 compared compare VBN cord-006870-f5w6fw6q 2865 9 with with IN cord-006870-f5w6fw6q 2865 10 standard standard JJ cord-006870-f5w6fw6q 2865 11 methods method NNS cord-006870-f5w6fw6q 2865 12 ( ( -LRB- cord-006870-f5w6fw6q 2865 13 Dry Dry NNP cord-006870-f5w6fw6q 2865 14 / / SYM cord-006870-f5w6fw6q 2865 15 Wet wet JJ cord-006870-f5w6fw6q 2865 16 brain brain NN cord-006870-f5w6fw6q 2865 17 weight weight NN cord-006870-f5w6fw6q 2865 18 ratio ratio NN cord-006870-f5w6fw6q 2865 19 ) ) -RRB- cord-006870-f5w6fw6q 2865 20 in in IN cord-006870-f5w6fw6q 2865 21 water water NN cord-006870-f5w6fw6q 2865 22 intoxication intoxication NN cord-006870-f5w6fw6q 2865 23 models model NNS cord-006870-f5w6fw6q 2865 24 ( ( -LRB- cord-006870-f5w6fw6q 2866 1 intraperitoneal intraperitoneal JJ cord-006870-f5w6fw6q 2866 2 injection injection NN cord-006870-f5w6fw6q 2866 3 of of IN cord-006870-f5w6fw6q 2866 4 distilled distilled JJ cord-006870-f5w6fw6q 2866 5 water water NN cord-006870-f5w6fw6q 2866 6 , , , cord-006870-f5w6fw6q 2866 7 20 20 CD cord-006870-f5w6fw6q 2866 8 % % NN cord-006870-f5w6fw6q 2866 9 of of IN cord-006870-f5w6fw6q 2866 10 body body NN cord-006870-f5w6fw6q 2866 11 weight weight NN cord-006870-f5w6fw6q 2866 12 ) ) -RRB- cord-006870-f5w6fw6q 2866 13 and and CC cord-006870-f5w6fw6q 2866 14 drying drying NN cord-006870-f5w6fw6q 2866 15 effect effect NN cord-006870-f5w6fw6q 2866 16 of of IN cord-006870-f5w6fw6q 2866 17 mannitol mannitol NN cord-006870-f5w6fw6q 2866 18 was be VBD cord-006870-f5w6fw6q 2866 19 validated validate VBN cord-006870-f5w6fw6q 2866 20 in in IN cord-006870-f5w6fw6q 2866 21 streptokinase streptokinase NNP cord-006870-f5w6fw6q 2866 22 induced induce VBD cord-006870-f5w6fw6q 2866 23 intracerebral intracerebral NNP cord-006870-f5w6fw6q 2866 24 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2866 25 ( ( -LRB- cord-006870-f5w6fw6q 2866 26 ICH ICH NNP cord-006870-f5w6fw6q 2866 27 ) ) -RRB- cord-006870-f5w6fw6q 2866 28 models model NNS cord-006870-f5w6fw6q 2866 29 . . . cord-006870-f5w6fw6q 2867 1 Calculated calculated JJ cord-006870-f5w6fw6q 2867 2 brain brain NN cord-006870-f5w6fw6q 2867 3 water water NN cord-006870-f5w6fw6q 2867 4 content content NN cord-006870-f5w6fw6q 2867 5 was be VBD cord-006870-f5w6fw6q 2867 6 78.6±0.6 78.6±0.6 CD cord-006870-f5w6fw6q 2867 7 % % NN cord-006870-f5w6fw6q 2867 8 in in IN cord-006870-f5w6fw6q 2867 9 thermal thermal JJ cord-006870-f5w6fw6q 2867 10 conductivity conductivity NN cord-006870-f5w6fw6q 2867 11 method method NN cord-006870-f5w6fw6q 2867 12 and and CC cord-006870-f5w6fw6q 2868 1 78.4±0.5 78.4±0.5 CD cord-006870-f5w6fw6q 2868 2 % % NN cord-006870-f5w6fw6q 2868 3 using use VBG cord-006870-f5w6fw6q 2868 4 Dry Dry NNP cord-006870-f5w6fw6q 2868 5 / / SYM cord-006870-f5w6fw6q 2868 6 Wet wet JJ cord-006870-f5w6fw6q 2868 7 weight weight NN cord-006870-f5w6fw6q 2868 8 ratio ratio NN cord-006870-f5w6fw6q 2868 9 methods method NNS cord-006870-f5w6fw6q 2868 10 ( ( -LRB- cord-006870-f5w6fw6q 2868 11 P=0.43 P=0.43 NNP cord-006870-f5w6fw6q 2868 12 ) ) -RRB- cord-006870-f5w6fw6q 2868 13 . . . cord-006870-f5w6fw6q 2869 1 In in IN cord-006870-f5w6fw6q 2869 2 water water NN cord-006870-f5w6fw6q 2869 3 intoxication intoxication NN cord-006870-f5w6fw6q 2869 4 model model NN cord-006870-f5w6fw6q 2869 5 , , , cord-006870-f5w6fw6q 2869 6 brain brain NN cord-006870-f5w6fw6q 2869 7 water water NN cord-006870-f5w6fw6q 2869 8 content content NN cord-006870-f5w6fw6q 2869 9 started start VBD cord-006870-f5w6fw6q 2869 10 to to TO cord-006870-f5w6fw6q 2869 11 increase increase VB cord-006870-f5w6fw6q 2869 12 30 30 CD cord-006870-f5w6fw6q 2869 13 minutes minute NNS cord-006870-f5w6fw6q 2869 14 after after IN cord-006870-f5w6fw6q 2869 15 injection injection NN cord-006870-f5w6fw6q 2869 16 and and CC cord-006870-f5w6fw6q 2869 17 reached reach VBD cord-006870-f5w6fw6q 2869 18 up up RP cord-006870-f5w6fw6q 2869 19 to to IN cord-006870-f5w6fw6q 2869 20 81.5±0.7 81.5±0.7 CD cord-006870-f5w6fw6q 2869 21 % % NN cord-006870-f5w6fw6q 2869 22 at at IN cord-006870-f5w6fw6q 2869 23 6 6 CD cord-006870-f5w6fw6q 2869 24 hours hour NNS cord-006870-f5w6fw6q 2869 25 post post NN cord-006870-f5w6fw6q 2869 26 injection injection NN cord-006870-f5w6fw6q 2869 27 . . . cord-006870-f5w6fw6q 2870 1 On on IN cord-006870-f5w6fw6q 2870 2 wet wet JJ cord-006870-f5w6fw6q 2870 3 / / SYM cord-006870-f5w6fw6q 2870 4 dry dry JJ cord-006870-f5w6fw6q 2870 5 weight weight NN cord-006870-f5w6fw6q 2870 6 method method NN cord-006870-f5w6fw6q 2870 7 , , , cord-006870-f5w6fw6q 2870 8 edema edema NN cord-006870-f5w6fw6q 2870 9 was be VBD cord-006870-f5w6fw6q 2870 10 measured measure VBN cord-006870-f5w6fw6q 2870 11 as as IN cord-006870-f5w6fw6q 2870 12 81.0±0.8 81.0±0.8 CD cord-006870-f5w6fw6q 2870 13 % % NN cord-006870-f5w6fw6q 2870 14 ( ( -LRB- cord-006870-f5w6fw6q 2870 15 P=0.80 P=0.80 NNP cord-006870-f5w6fw6q 2870 16 ) ) -RRB- cord-006870-f5w6fw6q 2870 17 . . . cord-006870-f5w6fw6q 2871 1 In in IN cord-006870-f5w6fw6q 2871 2 ICH ICH NNP cord-006870-f5w6fw6q 2871 3 model model NN cord-006870-f5w6fw6q 2871 4 , , , cord-006870-f5w6fw6q 2871 5 brain brain NN cord-006870-f5w6fw6q 2871 6 water water NN cord-006870-f5w6fw6q 2871 7 content content NN cord-006870-f5w6fw6q 2871 8 started start VBD cord-006870-f5w6fw6q 2871 9 to to TO cord-006870-f5w6fw6q 2871 10 drop drop VB cord-006870-f5w6fw6q 2871 11 30 30 CD cord-006870-f5w6fw6q 2871 12 minutes minute NNS cord-006870-f5w6fw6q 2871 13 after after IN cord-006870-f5w6fw6q 2871 14 administration administration NN cord-006870-f5w6fw6q 2871 15 of of IN cord-006870-f5w6fw6q 2871 16 mannitol mannitol NNP cord-006870-f5w6fw6q 2871 17 ( ( -LRB- cord-006870-f5w6fw6q 2871 18 0.5mg 0.5mg NNP cord-006870-f5w6fw6q 2871 19 / / SYM cord-006870-f5w6fw6q 2871 20 kg kg NNP cord-006870-f5w6fw6q 2871 21 ) ) -RRB- cord-006870-f5w6fw6q 2871 22 and and CC cord-006870-f5w6fw6q 2871 23 drifted drift VBD cord-006870-f5w6fw6q 2871 24 back back RB cord-006870-f5w6fw6q 2871 25 4 4 CD cord-006870-f5w6fw6q 2871 26 hours hour NNS cord-006870-f5w6fw6q 2871 27 after after IN cord-006870-f5w6fw6q 2871 28 injection injection NN cord-006870-f5w6fw6q 2871 29 of of IN cord-006870-f5w6fw6q 2871 30 mannitol mannitol NN cord-006870-f5w6fw6q 2871 31 . . . cord-006870-f5w6fw6q 2872 1 Thermal thermal JJ cord-006870-f5w6fw6q 2872 2 conductivity conductivity NN cord-006870-f5w6fw6q 2872 3 method method NN cord-006870-f5w6fw6q 2872 4 in in IN cord-006870-f5w6fw6q 2872 5 assessing assess VBG cord-006870-f5w6fw6q 2872 6 brain brain NN cord-006870-f5w6fw6q 2872 7 edema edema NN cord-006870-f5w6fw6q 2872 8 is be VBZ cord-006870-f5w6fw6q 2872 9 applicable applicable JJ cord-006870-f5w6fw6q 2872 10 in in IN cord-006870-f5w6fw6q 2872 11 rodents rodent NNS cord-006870-f5w6fw6q 2872 12 using use VBG cord-006870-f5w6fw6q 2872 13 suboccipital suboccipital JJ cord-006870-f5w6fw6q 2872 14 approach approach NN cord-006870-f5w6fw6q 2872 15 through through IN cord-006870-f5w6fw6q 2872 16 burr burr NNP cord-006870-f5w6fw6q 2872 17 hole hole NN cord-006870-f5w6fw6q 2872 18 . . . cord-006870-f5w6fw6q 2873 1 This this DT cord-006870-f5w6fw6q 2873 2 method method NN cord-006870-f5w6fw6q 2873 3 may may MD cord-006870-f5w6fw6q 2873 4 better better RB cord-006870-f5w6fw6q 2873 5 reflect reflect VB cord-006870-f5w6fw6q 2873 6 dynamic dynamic JJ cord-006870-f5w6fw6q 2873 7 changes change NNS cord-006870-f5w6fw6q 2873 8 of of IN cord-006870-f5w6fw6q 2873 9 brain brain NN cord-006870-f5w6fw6q 2873 10 edema edema NN cord-006870-f5w6fw6q 2873 11 . . . cord-006870-f5w6fw6q 2874 1 In in IN cord-006870-f5w6fw6q 2874 2 patients patient NNS cord-006870-f5w6fw6q 2874 3 with with IN cord-006870-f5w6fw6q 2874 4 critical critical JJ cord-006870-f5w6fw6q 2874 5 brain brain NN cord-006870-f5w6fw6q 2874 6 injury injury NN cord-006870-f5w6fw6q 2874 7 , , , cord-006870-f5w6fw6q 2874 8 alterations alteration NNS cord-006870-f5w6fw6q 2874 9 of of IN cord-006870-f5w6fw6q 2874 10 brain brain NN cord-006870-f5w6fw6q 2874 11 physiology physiology NN cord-006870-f5w6fw6q 2874 12 with with IN cord-006870-f5w6fw6q 2874 13 dialysis dialysis NN cord-006870-f5w6fw6q 2874 14 initiation initiation NN cord-006870-f5w6fw6q 2874 15 are be VBP cord-006870-f5w6fw6q 2874 16 poorly poorly RB cord-006870-f5w6fw6q 2874 17 understood understand VBN cord-006870-f5w6fw6q 2874 18 . . . cord-006870-f5w6fw6q 2875 1 From from IN cord-006870-f5w6fw6q 2875 2 a a DT cord-006870-f5w6fw6q 2875 3 consecutive consecutive JJ cord-006870-f5w6fw6q 2875 4 series series NN cord-006870-f5w6fw6q 2875 5 of of IN cord-006870-f5w6fw6q 2875 6 brain brain NN cord-006870-f5w6fw6q 2875 7 - - HYPH cord-006870-f5w6fw6q 2875 8 injured injure VBN cord-006870-f5w6fw6q 2875 9 patients patient NNS cord-006870-f5w6fw6q 2875 10 undergoing undergo VBG cord-006870-f5w6fw6q 2875 11 invasive invasive JJ cord-006870-f5w6fw6q 2875 12 multimodality multimodality NN cord-006870-f5w6fw6q 2875 13 monitoring monitoring NN cord-006870-f5w6fw6q 2875 14 between between IN cord-006870-f5w6fw6q 2875 15 2008 2008 CD cord-006870-f5w6fw6q 2875 16 and and CC cord-006870-f5w6fw6q 2875 17 2016 2016 CD cord-006870-f5w6fw6q 2875 18 , , , cord-006870-f5w6fw6q 2875 19 13 13 CD cord-006870-f5w6fw6q 2875 20 patients patient NNS cord-006870-f5w6fw6q 2875 21 that that WDT cord-006870-f5w6fw6q 2875 22 underwent undergo VBD cord-006870-f5w6fw6q 2875 23 continuous continuous JJ cord-006870-f5w6fw6q 2875 24 veno veno NNP cord-006870-f5w6fw6q 2875 25 - - HYPH cord-006870-f5w6fw6q 2875 26 venous venous JJ cord-006870-f5w6fw6q 2875 27 hemodialysis hemodialysis NN cord-006870-f5w6fw6q 2875 28 ( ( -LRB- cord-006870-f5w6fw6q 2875 29 CVVH CVVH NNP cord-006870-f5w6fw6q 2875 30 - - HYPH cord-006870-f5w6fw6q 2875 31 D D NNP cord-006870-f5w6fw6q 2875 32 ) ) -RRB- cord-006870-f5w6fw6q 2875 33 and and CC cord-006870-f5w6fw6q 2875 34 4 4 CD cord-006870-f5w6fw6q 2875 35 patients patient NNS cord-006870-f5w6fw6q 2875 36 that that WDT cord-006870-f5w6fw6q 2875 37 underwent undergo VBD cord-006870-f5w6fw6q 2875 38 intermittent intermittent JJ cord-006870-f5w6fw6q 2875 39 hemodialysis hemodialysis NN cord-006870-f5w6fw6q 2875 40 ( ( -LRB- cord-006870-f5w6fw6q 2875 41 iHD iHD NNP cord-006870-f5w6fw6q 2875 42 ) ) -RRB- cord-006870-f5w6fw6q 2875 43 were be VBD cord-006870-f5w6fw6q 2875 44 identified identify VBN cord-006870-f5w6fw6q 2875 45 . . . cord-006870-f5w6fw6q 2876 1 Changes change NNS cord-006870-f5w6fw6q 2876 2 in in IN cord-006870-f5w6fw6q 2876 3 mean mean JJ cord-006870-f5w6fw6q 2876 4 arterial arterial JJ cord-006870-f5w6fw6q 2876 5 pressure pressure NN cord-006870-f5w6fw6q 2876 6 ( ( -LRB- cord-006870-f5w6fw6q 2876 7 MAP MAP NNP cord-006870-f5w6fw6q 2876 8 ) ) -RRB- cord-006870-f5w6fw6q 2876 9 , , , cord-006870-f5w6fw6q 2876 10 intracranial intracranial JJ cord-006870-f5w6fw6q 2876 11 pressure pressure NN cord-006870-f5w6fw6q 2876 12 ( ( -LRB- cord-006870-f5w6fw6q 2876 13 ICP ICP NNP cord-006870-f5w6fw6q 2876 14 ) ) -RRB- cord-006870-f5w6fw6q 2876 15 , , , cord-006870-f5w6fw6q 2876 16 and and CC cord-006870-f5w6fw6q 2876 17 brain brain NN cord-006870-f5w6fw6q 2876 18 tissue tissue NN cord-006870-f5w6fw6q 2876 19 oxygenation oxygenation NN cord-006870-f5w6fw6q 2876 20 ( ( -LRB- cord-006870-f5w6fw6q 2876 21 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2876 22 ) ) -RRB- cord-006870-f5w6fw6q 2876 23 , , , cord-006870-f5w6fw6q 2876 24 and and CC cord-006870-f5w6fw6q 2876 25 microdialysis microdialysis NN cord-006870-f5w6fw6q 2876 26 lactate lactate NN cord-006870-f5w6fw6q 2876 27 - - HYPH cord-006870-f5w6fw6q 2876 28 pyruvate pyruvate NN cord-006870-f5w6fw6q 2876 29 ratio ratio NN cord-006870-f5w6fw6q 2876 30 ( ( -LRB- cord-006870-f5w6fw6q 2876 31 LPR LPR NNP cord-006870-f5w6fw6q 2876 32 ) ) -RRB- cord-006870-f5w6fw6q 2876 33 were be VBD cord-006870-f5w6fw6q 2876 34 compared compare VBN cord-006870-f5w6fw6q 2876 35 six six CD cord-006870-f5w6fw6q 2876 36 hours hour NNS cord-006870-f5w6fw6q 2876 37 prior prior RB cord-006870-f5w6fw6q 2876 38 to to IN cord-006870-f5w6fw6q 2876 39 and and CC cord-006870-f5w6fw6q 2876 40 twelve twelve CD cord-006870-f5w6fw6q 2876 41 hours hour NNS cord-006870-f5w6fw6q 2876 42 following follow VBG cord-006870-f5w6fw6q 2876 43 dialysis dialysis NN cord-006870-f5w6fw6q 2876 44 initiation initiation NN cord-006870-f5w6fw6q 2876 45 . . . cord-006870-f5w6fw6q 2877 1 High high JJ cord-006870-f5w6fw6q 2877 2 - - HYPH cord-006870-f5w6fw6q 2877 3 resolution resolution NN cord-006870-f5w6fw6q 2877 4 data datum NNS cord-006870-f5w6fw6q 2877 5 was be VBD cord-006870-f5w6fw6q 2877 6 collected collect VBN cord-006870-f5w6fw6q 2877 7 every every DT cord-006870-f5w6fw6q 2877 8 5 5 CD cord-006870-f5w6fw6q 2877 9 seconds second NNS cord-006870-f5w6fw6q 2877 10 , , , cord-006870-f5w6fw6q 2877 11 with with IN cord-006870-f5w6fw6q 2877 12 the the DT cord-006870-f5w6fw6q 2877 13 exception exception NN cord-006870-f5w6fw6q 2877 14 of of IN cord-006870-f5w6fw6q 2877 15 LPR LPR NNP cord-006870-f5w6fw6q 2877 16 collected collect VBD cord-006870-f5w6fw6q 2877 17 hourly hourly RB cord-006870-f5w6fw6q 2877 18 . . . cord-006870-f5w6fw6q 2878 1 Data datum NNS cord-006870-f5w6fw6q 2878 2 were be VBD cord-006870-f5w6fw6q 2878 3 normalized normalize VBN cord-006870-f5w6fw6q 2878 4 to to TO cord-006870-f5w6fw6q 2878 5 patient patient JJ cord-006870-f5w6fw6q 2878 6 maximum maximum JJ cord-006870-f5w6fw6q 2878 7 values value NNS cord-006870-f5w6fw6q 2878 8 , , , cord-006870-f5w6fw6q 2878 9 analyzed analyze VBN cord-006870-f5w6fw6q 2878 10 by by IN cord-006870-f5w6fw6q 2878 11 fitted fit VBN cord-006870-f5w6fw6q 2878 12 segmented segmented JJ cord-006870-f5w6fw6q 2878 13 regression regression NN cord-006870-f5w6fw6q 2878 14 , , , cord-006870-f5w6fw6q 2878 15 and and CC cord-006870-f5w6fw6q 2878 16 checked check VBD cord-006870-f5w6fw6q 2878 17 for for IN cord-006870-f5w6fw6q 2878 18 slope slope NN cord-006870-f5w6fw6q 2878 19 change change NN cord-006870-f5w6fw6q 2878 20 - - HYPH cord-006870-f5w6fw6q 2878 21 points point NNS cord-006870-f5w6fw6q 2878 22 by by IN cord-006870-f5w6fw6q 2878 23 Davies Davies NNP cord-006870-f5w6fw6q 2878 24 ' ' POS cord-006870-f5w6fw6q 2878 25 test test NN cord-006870-f5w6fw6q 2878 26 . . . cord-006870-f5w6fw6q 2879 1 Values value NNS cord-006870-f5w6fw6q 2879 2 prior prior RB cord-006870-f5w6fw6q 2879 3 to to IN cord-006870-f5w6fw6q 2879 4 dialysis dialysis NN cord-006870-f5w6fw6q 2879 5 initiation initiation NN cord-006870-f5w6fw6q 2879 6 were be VBD cord-006870-f5w6fw6q 2879 7 averaged average VBN cord-006870-f5w6fw6q 2879 8 as as IN cord-006870-f5w6fw6q 2879 9 a a DT cord-006870-f5w6fw6q 2879 10 baseline baseline NN cord-006870-f5w6fw6q 2879 11 for for IN cord-006870-f5w6fw6q 2879 12 comparison comparison NN cord-006870-f5w6fw6q 2879 13 . . . cord-006870-f5w6fw6q 2880 1 Median median JJ cord-006870-f5w6fw6q 2880 2 values value NNS cord-006870-f5w6fw6q 2880 3 for for IN cord-006870-f5w6fw6q 2880 4 patients patient NNS cord-006870-f5w6fw6q 2880 5 undergoing undergo VBG cord-006870-f5w6fw6q 2880 6 CVVH CVVH NNP cord-006870-f5w6fw6q 2880 7 - - HYPH cord-006870-f5w6fw6q 2880 8 D D NNP cord-006870-f5w6fw6q 2880 9 were be VBD cord-006870-f5w6fw6q 2880 10 MAP map NN cord-006870-f5w6fw6q 2880 11 85 85 CD cord-006870-f5w6fw6q 2881 1 + + CC cord-006870-f5w6fw6q 2881 2 /-12.77 /-12.77 . cord-006870-f5w6fw6q 2882 1 , , , cord-006870-f5w6fw6q 2882 2 ICP ICP NNP cord-006870-f5w6fw6q 2882 3 9.8+/-9.61 9.8+/-9.61 CD cord-006870-f5w6fw6q 2882 4 , , , cord-006870-f5w6fw6q 2882 5 pbtO2 pbto2 ADD cord-006870-f5w6fw6q 2883 1 21.7 21.7 CD cord-006870-f5w6fw6q 2883 2 + + SYM cord-006870-f5w6fw6q 2883 3 /-6.023 /-6.023 . cord-006870-f5w6fw6q 2883 4 mmHg mmHg NNP cord-006870-f5w6fw6q 2883 5 ( ( -LRB- cord-006870-f5w6fw6q 2883 6 n=5 n=5 NNP cord-006870-f5w6fw6q 2883 7 ) ) -RRB- cord-006870-f5w6fw6q 2883 8 , , , cord-006870-f5w6fw6q 2883 9 and and CC cord-006870-f5w6fw6q 2883 10 LPR LPR NNP cord-006870-f5w6fw6q 2883 11 21.6 21.6 CD cord-006870-f5w6fw6q 2884 1 + + UH cord-006870-f5w6fw6q 2884 2 /-22.13 /-22.13 . cord-006870-f5w6fw6q 2885 1 ( ( -LRB- cord-006870-f5w6fw6q 2885 2 n=4 n=4 NNP cord-006870-f5w6fw6q 2885 3 ) ) -RRB- cord-006870-f5w6fw6q 2885 4 . . . cord-006870-f5w6fw6q 2886 1 Normalized normalized JJ cord-006870-f5w6fw6q 2886 2 median median JJ cord-006870-f5w6fw6q 2886 3 values value NNS cord-006870-f5w6fw6q 2886 4 for for IN cord-006870-f5w6fw6q 2886 5 patients patient NNS cord-006870-f5w6fw6q 2886 6 undergoing undergo VBG cord-006870-f5w6fw6q 2886 7 iHD iHD NNP cord-006870-f5w6fw6q 2886 8 were be VBD cord-006870-f5w6fw6q 2886 9 MAP MAP NNP cord-006870-f5w6fw6q 2886 10 94 94 CD cord-006870-f5w6fw6q 2887 1 + + CC cord-006870-f5w6fw6q 2887 2 /-13.73 /-13.73 NN cord-006870-f5w6fw6q 2887 3 , , , cord-006870-f5w6fw6q 2887 4 ICP ICP NNP cord-006870-f5w6fw6q 2887 5 19 19 CD cord-006870-f5w6fw6q 2888 1 + + CC cord-006870-f5w6fw6q 2889 1 /-5.32 /-5.32 : cord-006870-f5w6fw6q 2889 2 . . . cord-006870-f5w6fw6q 2890 1 For for IN cord-006870-f5w6fw6q 2890 2 the the DT cord-006870-f5w6fw6q 2890 3 CVVH CVVH NNP cord-006870-f5w6fw6q 2890 4 patient patient NN cord-006870-f5w6fw6q 2890 5 segmented segment VBN cord-006870-f5w6fw6q 2890 6 regressions regression NNS cord-006870-f5w6fw6q 2890 7 with with IN cord-006870-f5w6fw6q 2890 8 normalized normalized JJ cord-006870-f5w6fw6q 2890 9 data datum NNS cord-006870-f5w6fw6q 2890 10 , , , cord-006870-f5w6fw6q 2890 11 there there EX cord-006870-f5w6fw6q 2890 12 was be VBD cord-006870-f5w6fw6q 2890 13 no no DT cord-006870-f5w6fw6q 2890 14 change change NN cord-006870-f5w6fw6q 2890 15 in in IN cord-006870-f5w6fw6q 2890 16 MAP MAP NNP cord-006870-f5w6fw6q 2890 17 ( ( -LRB- cord-006870-f5w6fw6q 2890 18 slope slope NN cord-006870-f5w6fw6q 2890 19 0.0004 0.0004 CD cord-006870-f5w6fw6q 2890 20 ) ) -RRB- cord-006870-f5w6fw6q 2890 21 during during IN cord-006870-f5w6fw6q 2890 22 the the DT cord-006870-f5w6fw6q 2890 23 twelve twelve CD cord-006870-f5w6fw6q 2890 24 hours hour NNS cord-006870-f5w6fw6q 2890 25 . . . cord-006870-f5w6fw6q 2891 1 However however RB cord-006870-f5w6fw6q 2891 2 , , , cord-006870-f5w6fw6q 2891 3 we -PRON- PRP cord-006870-f5w6fw6q 2891 4 found find VBD cord-006870-f5w6fw6q 2891 5 a a DT cord-006870-f5w6fw6q 2891 6 change change NN cord-006870-f5w6fw6q 2891 7 - - HYPH cord-006870-f5w6fw6q 2891 8 point point NN cord-006870-f5w6fw6q 2891 9 in in IN cord-006870-f5w6fw6q 2891 10 ICP ICP NNP cord-006870-f5w6fw6q 2891 11 at at IN cord-006870-f5w6fw6q 2891 12 4.78 4.78 CD cord-006870-f5w6fw6q 2891 13 hours hour NNS cord-006870-f5w6fw6q 2891 14 ( ( -LRB- cord-006870-f5w6fw6q 2891 15 CI CI NNP cord-006870-f5w6fw6q 2891 16 3.76 3.76 CD cord-006870-f5w6fw6q 2891 17 - - HYPH cord-006870-f5w6fw6q 2891 18 5.79 5.79 CD cord-006870-f5w6fw6q 2891 19 , , , cord-006870-f5w6fw6q 2891 20 slope slope NN cord-006870-f5w6fw6q 2891 21 change change NN cord-006870-f5w6fw6q 2891 22 0.006 0.006 CD cord-006870-f5w6fw6q 2891 23 to to IN cord-006870-f5w6fw6q 2891 24 0.0006 0.0006 CD cord-006870-f5w6fw6q 2891 25 ) ) -RRB- cord-006870-f5w6fw6q 2891 26 and and CC cord-006870-f5w6fw6q 2891 27 pbtO2 pbtO2 NNS cord-006870-f5w6fw6q 2891 28 at at IN cord-006870-f5w6fw6q 2891 29 4.99 4.99 CD cord-006870-f5w6fw6q 2891 30 hours hour NNS cord-006870-f5w6fw6q 2891 31 , , , cord-006870-f5w6fw6q 2891 32 slope slope NN cord-006870-f5w6fw6q 2891 33 change change NN cord-006870-f5w6fw6q 2891 34 0.006 0.006 CD cord-006870-f5w6fw6q 2891 35 to to IN cord-006870-f5w6fw6q 2891 36 -0.023 -0.023 ADD cord-006870-f5w6fw6q 2891 37 ) ) -RRB- cord-006870-f5w6fw6q 2891 38 . . . cord-006870-f5w6fw6q 2892 1 LPR LPR NNP cord-006870-f5w6fw6q 2892 2 increased increase VBD cord-006870-f5w6fw6q 2892 3 through through IN cord-006870-f5w6fw6q 2892 4 CVVH CVVH NNP cord-006870-f5w6fw6q 2892 5 ( ( -LRB- cord-006870-f5w6fw6q 2892 6 slope slope NN cord-006870-f5w6fw6q 2892 7 0.036 0.036 CD cord-006870-f5w6fw6q 2892 8 + + CD cord-006870-f5w6fw6q 2892 9 /-0.0097 /-0.0097 NN cord-006870-f5w6fw6q 2892 10 ) ) -RRB- cord-006870-f5w6fw6q 2892 11 . . . cord-006870-f5w6fw6q 2893 1 Median median JJ cord-006870-f5w6fw6q 2893 2 values value NNS cord-006870-f5w6fw6q 2893 3 for for IN cord-006870-f5w6fw6q 2893 4 patients patient NNS cord-006870-f5w6fw6q 2893 5 undergoing undergo VBG cord-006870-f5w6fw6q 2893 6 iHD iHD NNP cord-006870-f5w6fw6q 2893 7 were be VBD cord-006870-f5w6fw6q 2893 8 MAP MAP NNP cord-006870-f5w6fw6q 2893 9 94 94 CD cord-006870-f5w6fw6q 2894 1 + + CC cord-006870-f5w6fw6q 2894 2 /-13.73 /-13.73 NN cord-006870-f5w6fw6q 2894 3 , , , cord-006870-f5w6fw6q 2894 4 ICP ICP NNP cord-006870-f5w6fw6q 2894 5 19 19 CD cord-006870-f5w6fw6q 2894 6 + + CC cord-006870-f5w6fw6q 2894 7 /-5.315 /-5.315 . cord-006870-f5w6fw6q 2894 8 . . . cord-006870-f5w6fw6q 2895 1 There there EX cord-006870-f5w6fw6q 2895 2 was be VBD cord-006870-f5w6fw6q 2895 3 no no DT cord-006870-f5w6fw6q 2895 4 identified identify VBN cord-006870-f5w6fw6q 2895 5 change change NN cord-006870-f5w6fw6q 2895 6 - - HYPH cord-006870-f5w6fw6q 2895 7 points point NNS cord-006870-f5w6fw6q 2895 8 in in IN cord-006870-f5w6fw6q 2895 9 MAP MAP NNP cord-006870-f5w6fw6q 2895 10 or or CC cord-006870-f5w6fw6q 2895 11 ICP ICP NNP cord-006870-f5w6fw6q 2895 12 in in IN cord-006870-f5w6fw6q 2895 13 iHD ihd NN cord-006870-f5w6fw6q 2895 14 patients patient NNS cord-006870-f5w6fw6q 2895 15 , , , cord-006870-f5w6fw6q 2895 16 further further JJ cord-006870-f5w6fw6q 2895 17 parameters parameter NNS cord-006870-f5w6fw6q 2895 18 were be VBD cord-006870-f5w6fw6q 2895 19 limited limit VBN cord-006870-f5w6fw6q 2895 20 by by IN cord-006870-f5w6fw6q 2895 21 small small JJ cord-006870-f5w6fw6q 2895 22 sample sample NN cord-006870-f5w6fw6q 2895 23 size size NN cord-006870-f5w6fw6q 2895 24 . . . cord-006870-f5w6fw6q 2896 1 Initiation initiation NN cord-006870-f5w6fw6q 2896 2 of of IN cord-006870-f5w6fw6q 2896 3 CVVH CVVH NNP cord-006870-f5w6fw6q 2896 4 in in IN cord-006870-f5w6fw6q 2896 5 patients patient NNS cord-006870-f5w6fw6q 2896 6 with with IN cord-006870-f5w6fw6q 2896 7 neurologic neurologic JJ cord-006870-f5w6fw6q 2896 8 multimodality multimodality NN cord-006870-f5w6fw6q 2896 9 monitoring monitoring NN cord-006870-f5w6fw6q 2896 10 showed show VBD cord-006870-f5w6fw6q 2896 11 change change NN cord-006870-f5w6fw6q 2896 12 - - HYPH cord-006870-f5w6fw6q 2896 13 points point NNS cord-006870-f5w6fw6q 2896 14 in in IN cord-006870-f5w6fw6q 2896 15 ICP ICP NNP cord-006870-f5w6fw6q 2896 16 and and CC cord-006870-f5w6fw6q 2896 17 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2896 18 in in IN cord-006870-f5w6fw6q 2896 19 setting set VBG cord-006870-f5w6fw6q 2896 20 of of IN cord-006870-f5w6fw6q 2896 21 stable stable JJ cord-006870-f5w6fw6q 2896 22 MAP MAP NNP cord-006870-f5w6fw6q 2896 23 , , , cord-006870-f5w6fw6q 2896 24 with with IN cord-006870-f5w6fw6q 2896 25 slight slight JJ cord-006870-f5w6fw6q 2896 26 decrease decrease NN cord-006870-f5w6fw6q 2896 27 in in IN cord-006870-f5w6fw6q 2896 28 ICP ICP NNP cord-006870-f5w6fw6q 2896 29 and and CC cord-006870-f5w6fw6q 2896 30 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2896 31 . . . cord-006870-f5w6fw6q 2897 1 Initiation initiation NN cord-006870-f5w6fw6q 2897 2 of of IN cord-006870-f5w6fw6q 2897 3 HD HD NNP cord-006870-f5w6fw6q 2897 4 in in IN cord-006870-f5w6fw6q 2897 5 showed show VBD cord-006870-f5w6fw6q 2897 6 no no DT cord-006870-f5w6fw6q 2897 7 change change NN cord-006870-f5w6fw6q 2897 8 - - HYPH cord-006870-f5w6fw6q 2897 9 points point NNS cord-006870-f5w6fw6q 2897 10 in in IN cord-006870-f5w6fw6q 2897 11 ICP ICP NNP cord-006870-f5w6fw6q 2897 12 . . . cord-006870-f5w6fw6q 2898 1 Data datum NNS cord-006870-f5w6fw6q 2898 2 on on IN cord-006870-f5w6fw6q 2898 3 the the DT cord-006870-f5w6fw6q 2898 4 cerebral cerebral JJ cord-006870-f5w6fw6q 2898 5 effects effect NNS cord-006870-f5w6fw6q 2898 6 of of IN cord-006870-f5w6fw6q 2898 7 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 2898 8 agents agent NNS cord-006870-f5w6fw6q 2898 9 are be VBP cord-006870-f5w6fw6q 2898 10 limited limited JJ cord-006870-f5w6fw6q 2898 11 but but CC cord-006870-f5w6fw6q 2898 12 potentially potentially RB cord-006870-f5w6fw6q 2898 13 important important JJ cord-006870-f5w6fw6q 2898 14 in in IN cord-006870-f5w6fw6q 2898 15 patients patient NNS cord-006870-f5w6fw6q 2898 16 requiring require VBG cord-006870-f5w6fw6q 2898 17 blood blood NN cord-006870-f5w6fw6q 2898 18 pressure pressure NN cord-006870-f5w6fw6q 2898 19 reduction reduction NN cord-006870-f5w6fw6q 2898 20 in in IN cord-006870-f5w6fw6q 2898 21 neurological neurological JJ cord-006870-f5w6fw6q 2898 22 emergencies emergency NNS cord-006870-f5w6fw6q 2898 23 . . . cord-006870-f5w6fw6q 2899 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2899 2 objective objective NN cord-006870-f5w6fw6q 2899 3 was be VBD cord-006870-f5w6fw6q 2899 4 to to TO cord-006870-f5w6fw6q 2899 5 measure measure VB cord-006870-f5w6fw6q 2899 6 the the DT cord-006870-f5w6fw6q 2899 7 effect effect NN cord-006870-f5w6fw6q 2899 8 of of IN cord-006870-f5w6fw6q 2899 9 rapid rapid JJ cord-006870-f5w6fw6q 2899 10 - - HYPH cord-006870-f5w6fw6q 2899 11 acting act VBG cord-006870-f5w6fw6q 2899 12 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 2899 13 agents agent NNS cord-006870-f5w6fw6q 2899 14 on on IN cord-006870-f5w6fw6q 2899 15 cerebral cerebral JJ cord-006870-f5w6fw6q 2899 16 blood blood NN cord-006870-f5w6fw6q 2899 17 flow flow NN cord-006870-f5w6fw6q 2899 18 ( ( -LRB- cord-006870-f5w6fw6q 2899 19 CBF CBF NNP cord-006870-f5w6fw6q 2899 20 ) ) -RRB- cord-006870-f5w6fw6q 2899 21 in in IN cord-006870-f5w6fw6q 2899 22 patients patient NNS cord-006870-f5w6fw6q 2899 23 with with IN cord-006870-f5w6fw6q 2899 24 acute acute JJ cord-006870-f5w6fw6q 2899 25 hypertension hypertension NN cord-006870-f5w6fw6q 2899 26 We -PRON- PRP cord-006870-f5w6fw6q 2899 27 conducted conduct VBD cord-006870-f5w6fw6q 2899 28 a a DT cord-006870-f5w6fw6q 2899 29 prospective prospective JJ cord-006870-f5w6fw6q 2899 30 , , , cord-006870-f5w6fw6q 2899 31 quasi quasi JJ cord-006870-f5w6fw6q 2899 32 - - JJ cord-006870-f5w6fw6q 2899 33 experimental experimental JJ cord-006870-f5w6fw6q 2899 34 study study NN cord-006870-f5w6fw6q 2899 35 of of IN cord-006870-f5w6fw6q 2899 36 patients patient NNS cord-006870-f5w6fw6q 2899 37 with with IN cord-006870-f5w6fw6q 2899 38 a a DT cord-006870-f5w6fw6q 2899 39 SBP SBP NNP cord-006870-f5w6fw6q 2899 40 > > XX cord-006870-f5w6fw6q 2899 41 180 180 CD cord-006870-f5w6fw6q 2899 42 mmHg mmHg NNS cord-006870-f5w6fw6q 2899 43 and and CC cord-006870-f5w6fw6q 2899 44 planned plan VBN cord-006870-f5w6fw6q 2899 45 rapid rapid RB cord-006870-f5w6fw6q 2899 46 - - HYPH cord-006870-f5w6fw6q 2899 47 acting act VBG cord-006870-f5w6fw6q 2899 48 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 2899 49 treatment treatment NN cord-006870-f5w6fw6q 2899 50 in in IN cord-006870-f5w6fw6q 2899 51 the the DT cord-006870-f5w6fw6q 2899 52 emergency emergency NN cord-006870-f5w6fw6q 2899 53 department department NN cord-006870-f5w6fw6q 2899 54 . . . cord-006870-f5w6fw6q 2900 1 Patients patient NNS cord-006870-f5w6fw6q 2901 1 < < NNP cord-006870-f5w6fw6q 2901 2 18 18 CD cord-006870-f5w6fw6q 2901 3 years year NNS cord-006870-f5w6fw6q 2901 4 or or CC cord-006870-f5w6fw6q 2901 5 pregnant pregnant JJ cord-006870-f5w6fw6q 2901 6 were be VBD cord-006870-f5w6fw6q 2901 7 excluded exclude VBN cord-006870-f5w6fw6q 2901 8 . . . cord-006870-f5w6fw6q 2902 1 Non non JJ cord-006870-f5w6fw6q 2902 2 - - JJ cord-006870-f5w6fw6q 2902 3 invasive invasive JJ cord-006870-f5w6fw6q 2902 4 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 2902 5 and and CC cord-006870-f5w6fw6q 2902 6 transcranial transcranial JJ cord-006870-f5w6fw6q 2902 7 Doppler Doppler NNP cord-006870-f5w6fw6q 2902 8 measurements measurement NNS cord-006870-f5w6fw6q 2902 9 of of IN cord-006870-f5w6fw6q 2902 10 the the DT cord-006870-f5w6fw6q 2902 11 middle middle JJ cord-006870-f5w6fw6q 2902 12 cerebral cerebral JJ cord-006870-f5w6fw6q 2902 13 artery artery NN cord-006870-f5w6fw6q 2902 14 mean mean JJ cord-006870-f5w6fw6q 2902 15 flow flow NN cord-006870-f5w6fw6q 2902 16 velocity velocity NN cord-006870-f5w6fw6q 2902 17 ( ( -LRB- cord-006870-f5w6fw6q 2902 18 MFV MFV NNP cord-006870-f5w6fw6q 2902 19 ) ) -RRB- cord-006870-f5w6fw6q 2902 20 were be VBD cord-006870-f5w6fw6q 2902 21 obtained obtain VBN cord-006870-f5w6fw6q 2902 22 prior prior RB cord-006870-f5w6fw6q 2902 23 to to IN cord-006870-f5w6fw6q 2902 24 and and CC cord-006870-f5w6fw6q 2902 25 post post NN cord-006870-f5w6fw6q 2902 26 treatment treatment NN cord-006870-f5w6fw6q 2902 27 . . . cord-006870-f5w6fw6q 2903 1 Analysis analysis NN cord-006870-f5w6fw6q 2903 2 included include VBD cord-006870-f5w6fw6q 2903 3 descriptive descriptive JJ cord-006870-f5w6fw6q 2903 4 statistics statistic NNS cord-006870-f5w6fw6q 2903 5 and and CC cord-006870-f5w6fw6q 2903 6 generalized generalized JJ cord-006870-f5w6fw6q 2903 7 linear linear JJ cord-006870-f5w6fw6q 2903 8 modeling modeling NN cord-006870-f5w6fw6q 2903 9 to to TO cord-006870-f5w6fw6q 2903 10 test test VB cord-006870-f5w6fw6q 2903 11 the the DT cord-006870-f5w6fw6q 2903 12 effect effect NN cord-006870-f5w6fw6q 2903 13 of of IN cord-006870-f5w6fw6q 2903 14 four four CD cord-006870-f5w6fw6q 2903 15 categories category NNS cord-006870-f5w6fw6q 2903 16 of of IN cord-006870-f5w6fw6q 2903 17 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 2903 18 agents agent NNS cord-006870-f5w6fw6q 2903 19 on on IN cord-006870-f5w6fw6q 2903 20 MFV MFV NNP cord-006870-f5w6fw6q 2903 21 . . . cord-006870-f5w6fw6q 2904 1 Categories category NNS cord-006870-f5w6fw6q 2904 2 included include VBD cord-006870-f5w6fw6q 2904 3 clonidine clonidine NN cord-006870-f5w6fw6q 2904 4 , , , cord-006870-f5w6fw6q 2904 5 IV IV NNP cord-006870-f5w6fw6q 2904 6 labetalol labetalol NNP cord-006870-f5w6fw6q 2904 7 , , , cord-006870-f5w6fw6q 2904 8 IV IV NNP cord-006870-f5w6fw6q 2904 9 hydralazine hydralazine NNP cord-006870-f5w6fw6q 2904 10 and and CC cord-006870-f5w6fw6q 2904 11 combination combination NN cord-006870-f5w6fw6q 2904 12 therapy therapy NN cord-006870-f5w6fw6q 2904 13 . . . cord-006870-f5w6fw6q 2905 1 We -PRON- PRP cord-006870-f5w6fw6q 2905 2 enrolled enrol VBD cord-006870-f5w6fw6q 2905 3 35 35 CD cord-006870-f5w6fw6q 2905 4 patients patient NNS cord-006870-f5w6fw6q 2905 5 ( ( -LRB- cord-006870-f5w6fw6q 2905 6 37 37 CD cord-006870-f5w6fw6q 2905 7 % % NN cord-006870-f5w6fw6q 2905 8 female female NN cord-006870-f5w6fw6q 2905 9 ) ) -RRB- cord-006870-f5w6fw6q 2905 10 with with IN cord-006870-f5w6fw6q 2905 11 a a DT cord-006870-f5w6fw6q 2905 12 mean mean JJ cord-006870-f5w6fw6q 2905 13 age age NN cord-006870-f5w6fw6q 2905 14 of of IN cord-006870-f5w6fw6q 2905 15 49 49 CD cord-006870-f5w6fw6q 2905 16 ± ± CD cord-006870-f5w6fw6q 2905 17 13 13 CD cord-006870-f5w6fw6q 2905 18 years year NNS cord-006870-f5w6fw6q 2905 19 . . . cord-006870-f5w6fw6q 2906 1 Eight eight CD cord-006870-f5w6fw6q 2906 2 ( ( -LRB- cord-006870-f5w6fw6q 2906 3 23 23 CD cord-006870-f5w6fw6q 2906 4 % % NN cord-006870-f5w6fw6q 2906 5 ) ) -RRB- cord-006870-f5w6fw6q 2907 1 patients patient NNS cord-006870-f5w6fw6q 2907 2 received receive VBD cord-006870-f5w6fw6q 2907 3 clonidine clonidine NN cord-006870-f5w6fw6q 2907 4 , , , cord-006870-f5w6fw6q 2907 5 6 6 CD cord-006870-f5w6fw6q 2907 6 ( ( -LRB- cord-006870-f5w6fw6q 2907 7 17 17 CD cord-006870-f5w6fw6q 2907 8 % % NN cord-006870-f5w6fw6q 2907 9 ) ) -RRB- cord-006870-f5w6fw6q 2908 1 IV IV NNP cord-006870-f5w6fw6q 2908 2 labetalol labetalol NNP cord-006870-f5w6fw6q 2908 3 , , , cord-006870-f5w6fw6q 2908 4 5 5 CD cord-006870-f5w6fw6q 2908 5 ( ( -LRB- cord-006870-f5w6fw6q 2908 6 14 14 CD cord-006870-f5w6fw6q 2908 7 % % NN cord-006870-f5w6fw6q 2908 8 ) ) -RRB- cord-006870-f5w6fw6q 2909 1 IV IV NNP cord-006870-f5w6fw6q 2909 2 hydralazine hydralazine NNP cord-006870-f5w6fw6q 2909 3 and and CC cord-006870-f5w6fw6q 2909 4 16 16 CD cord-006870-f5w6fw6q 2909 5 ( ( -LRB- cord-006870-f5w6fw6q 2909 6 46 46 CD cord-006870-f5w6fw6q 2909 7 % % NN cord-006870-f5w6fw6q 2909 8 ) ) -RRB- cord-006870-f5w6fw6q 2909 9 combined combine VBN cord-006870-f5w6fw6q 2909 10 therapy therapy NN cord-006870-f5w6fw6q 2909 11 . . . cord-006870-f5w6fw6q 2910 1 The the DT cord-006870-f5w6fw6q 2910 2 mean mean JJ cord-006870-f5w6fw6q 2910 3 baseline baseline JJ cord-006870-f5w6fw6q 2910 4 SBP SBP NNP cord-006870-f5w6fw6q 2910 5 was be VBD cord-006870-f5w6fw6q 2910 6 214 214 CD cord-006870-f5w6fw6q 2910 7 ± ± CD cord-006870-f5w6fw6q 2910 8 24 24 CD cord-006870-f5w6fw6q 2910 9 mmHg mmHg NNS cord-006870-f5w6fw6q 2910 10 and and CC cord-006870-f5w6fw6q 2910 11 MFV MFV NNP cord-006870-f5w6fw6q 2910 12 49 49 CD cord-006870-f5w6fw6q 2910 13 ± ± NNP cord-006870-f5w6fw6q 2910 14 13 13 CD cord-006870-f5w6fw6q 2910 15 cm cm NNS cord-006870-f5w6fw6q 2910 16 / / SYM cord-006870-f5w6fw6q 2910 17 sec sec NNP cord-006870-f5w6fw6q 2910 18 . . . cord-006870-f5w6fw6q 2911 1 The the DT cord-006870-f5w6fw6q 2911 2 mean mean JJ cord-006870-f5w6fw6q 2911 3 percentage percentage NN cord-006870-f5w6fw6q 2911 4 fall fall NN cord-006870-f5w6fw6q 2911 5 in in IN cord-006870-f5w6fw6q 2911 6 SBP SBP NNP cord-006870-f5w6fw6q 2911 7 by by IN cord-006870-f5w6fw6q 2911 8 medication medication NN cord-006870-f5w6fw6q 2911 9 was be VBD cord-006870-f5w6fw6q 2911 10 : : : cord-006870-f5w6fw6q 2911 11 clonidine clonidine NN cord-006870-f5w6fw6q 2911 12 -12 -12 : cord-006870-f5w6fw6q 2911 13 ±7 ±7 NNS cord-006870-f5w6fw6q 2911 14 % % NN cord-006870-f5w6fw6q 2911 15 , , , cord-006870-f5w6fw6q 2911 16 labetalol labetalol NN cord-006870-f5w6fw6q 2911 17 -13 -13 CD cord-006870-f5w6fw6q 2912 1 ±12 ±12 NNP cord-006870-f5w6fw6q 2912 2 % % NN cord-006870-f5w6fw6q 2912 3 , , , cord-006870-f5w6fw6q 2912 4 hydralazine hydralazine NNP cord-006870-f5w6fw6q 2912 5 -23 -23 NNP cord-006870-f5w6fw6q 2912 6 ±11 ±11 NNP cord-006870-f5w6fw6q 2912 7 % % NN cord-006870-f5w6fw6q 2912 8 , , , cord-006870-f5w6fw6q 2912 9 and and CC cord-006870-f5w6fw6q 2912 10 combination combination NN cord-006870-f5w6fw6q 2912 11 -23 -23 NN cord-006870-f5w6fw6q 2913 1 ±16 ±16 NNP cord-006870-f5w6fw6q 2913 2 % % NN cord-006870-f5w6fw6q 2913 3 . . . cord-006870-f5w6fw6q 2914 1 The the DT cord-006870-f5w6fw6q 2914 2 overall overall JJ cord-006870-f5w6fw6q 2914 3 change change NN cord-006870-f5w6fw6q 2914 4 in in IN cord-006870-f5w6fw6q 2914 5 MFV MFV NNP cord-006870-f5w6fw6q 2914 6 was be VBD cord-006870-f5w6fw6q 2914 7 -9 -9 NNP cord-006870-f5w6fw6q 2914 8 ±15 ±15 NNP cord-006870-f5w6fw6q 2914 9 % % NN cord-006870-f5w6fw6q 2914 10 , , , cord-006870-f5w6fw6q 2914 11 and and CC cord-006870-f5w6fw6q 2914 12 by by IN cord-006870-f5w6fw6q 2914 13 medication medication NN cord-006870-f5w6fw6q 2914 14 was be VBD cord-006870-f5w6fw6q 2914 15 : : : cord-006870-f5w6fw6q 2914 16 clonidine clonidine NN cord-006870-f5w6fw6q 2914 17 -10 -10 CD cord-006870-f5w6fw6q 2914 18 % % NN cord-006870-f5w6fw6q 2914 19 ( ( -LRB- cord-006870-f5w6fw6q 2914 20 95%CI 95%ci CD cord-006870-f5w6fw6q 2914 21 -2 -2 CD cord-006870-f5w6fw6q 2914 22 to to IN cord-006870-f5w6fw6q 2914 23 -21 -21 NN cord-006870-f5w6fw6q 2914 24 % % NN cord-006870-f5w6fw6q 2914 25 ) ) -RRB- cord-006870-f5w6fw6q 2914 26 , , , cord-006870-f5w6fw6q 2914 27 labetalol labetalol NN cord-006870-f5w6fw6q 2914 28 -11 -11 IN cord-006870-f5w6fw6q 2914 29 % % NN cord-006870-f5w6fw6q 2914 30 ( ( -LRB- cord-006870-f5w6fw6q 2914 31 95%CI 95%ci CD cord-006870-f5w6fw6q 2914 32 -5 -5 CD cord-006870-f5w6fw6q 2914 33 to to IN cord-006870-f5w6fw6q 2914 34 -27 -27 CD cord-006870-f5w6fw6q 2914 35 % % NN cord-006870-f5w6fw6q 2914 36 ) ) -RRB- cord-006870-f5w6fw6q 2914 37 , , . cord-006870-f5w6fw6q 2915 1 hydralazine hydralazine NNP cord-006870-f5w6fw6q 2915 2 +1 +1 HYPH cord-006870-f5w6fw6q 2915 3 % % NN cord-006870-f5w6fw6q 2915 4 ( ( -LRB- cord-006870-f5w6fw6q 2915 5 95%CI 95%ci CD cord-006870-f5w6fw6q 2915 6 -18 -18 NN cord-006870-f5w6fw6q 2915 7 to to IN cord-006870-f5w6fw6q 2915 8 +21 +21 CD cord-006870-f5w6fw6q 2915 9 % % NN cord-006870-f5w6fw6q 2915 10 ) ) -RRB- cord-006870-f5w6fw6q 2915 11 , , , cord-006870-f5w6fw6q 2915 12 and and CC cord-006870-f5w6fw6q 2915 13 combination combination NN cord-006870-f5w6fw6q 2915 14 -11 -11 IN cord-006870-f5w6fw6q 2915 15 % % NN cord-006870-f5w6fw6q 2915 16 ( ( -LRB- cord-006870-f5w6fw6q 2915 17 95%CI 95%ci CD cord-006870-f5w6fw6q 2915 18 -2 -2 CD cord-006870-f5w6fw6q 2915 19 to to IN cord-006870-f5w6fw6q 2915 20 -19 -19 `` cord-006870-f5w6fw6q 2915 21 % % NN cord-006870-f5w6fw6q 2915 22 ) ) -RRB- cord-006870-f5w6fw6q 2915 23 . . . cord-006870-f5w6fw6q 2916 1 Adjusting adjust VBG cord-006870-f5w6fw6q 2916 2 for for IN cord-006870-f5w6fw6q 2916 3 baseline baseline JJ cord-006870-f5w6fw6q 2916 4 BP BP NNP cord-006870-f5w6fw6q 2916 5 , , , cord-006870-f5w6fw6q 2916 6 hydralazine hydralazine NNP cord-006870-f5w6fw6q 2916 7 caused cause VBD cord-006870-f5w6fw6q 2916 8 less less JJR cord-006870-f5w6fw6q 2916 9 change change NN cord-006870-f5w6fw6q 2916 10 in in IN cord-006870-f5w6fw6q 2916 11 MFV MFV NNP cord-006870-f5w6fw6q 2916 12 compared compare VBN cord-006870-f5w6fw6q 2916 13 to to IN cord-006870-f5w6fw6q 2916 14 other other JJ cord-006870-f5w6fw6q 2916 15 medications medication NNS cord-006870-f5w6fw6q 2916 16 ( ( -LRB- cord-006870-f5w6fw6q 2916 17 difference difference NN cord-006870-f5w6fw6q 2916 18 between between IN cord-006870-f5w6fw6q 2916 19 means mean NNS cord-006870-f5w6fw6q 2916 20 +12 +12 CD cord-006870-f5w6fw6q 2916 21 % % NN cord-006870-f5w6fw6q 2916 22 , , , cord-006870-f5w6fw6q 2916 23 95%CI 95%ci CD cord-006870-f5w6fw6q 2916 24 -3 -3 NN cord-006870-f5w6fw6q 2916 25 to to IN cord-006870-f5w6fw6q 2916 26 +26 +26 CD cord-006870-f5w6fw6q 2916 27 % % NN cord-006870-f5w6fw6q 2916 28 , , , cord-006870-f5w6fw6q 2916 29 p=0.1 p=0.1 NNP cord-006870-f5w6fw6q 2916 30 ) ) -RRB- cord-006870-f5w6fw6q 2916 31 . . . cord-006870-f5w6fw6q 2917 1 In in IN cord-006870-f5w6fw6q 2917 2 this this DT cord-006870-f5w6fw6q 2917 3 study study NN cord-006870-f5w6fw6q 2917 4 with with IN cord-006870-f5w6fw6q 2917 5 modest modest JJ cord-006870-f5w6fw6q 2917 6 BP BP NNP cord-006870-f5w6fw6q 2917 7 reductions reduction NNS cord-006870-f5w6fw6q 2917 8 , , , cord-006870-f5w6fw6q 2917 9 rapid rapid RB cord-006870-f5w6fw6q 2917 10 - - HYPH cord-006870-f5w6fw6q 2917 11 acting act VBG cord-006870-f5w6fw6q 2917 12 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 2917 13 medications medication NNS cord-006870-f5w6fw6q 2917 14 had have VBD cord-006870-f5w6fw6q 2917 15 comparable comparable JJ cord-006870-f5w6fw6q 2917 16 effects effect NNS cord-006870-f5w6fw6q 2917 17 on on IN cord-006870-f5w6fw6q 2917 18 cerebral cerebral JJ cord-006870-f5w6fw6q 2917 19 blood blood NN cord-006870-f5w6fw6q 2917 20 flow flow NN cord-006870-f5w6fw6q 2917 21 . . . cord-006870-f5w6fw6q 2918 1 These these DT cord-006870-f5w6fw6q 2918 2 results result NNS cord-006870-f5w6fw6q 2918 3 hint hint VBP cord-006870-f5w6fw6q 2918 4 that that IN cord-006870-f5w6fw6q 2918 5 cerebral cerebral JJ cord-006870-f5w6fw6q 2918 6 blood blood NN cord-006870-f5w6fw6q 2918 7 flow flow NN cord-006870-f5w6fw6q 2918 8 may may MD cord-006870-f5w6fw6q 2918 9 be be VB cord-006870-f5w6fw6q 2918 10 more more RBR cord-006870-f5w6fw6q 2918 11 stable stable JJ cord-006870-f5w6fw6q 2918 12 with with IN cord-006870-f5w6fw6q 2918 13 hydralazine hydralazine NNP cord-006870-f5w6fw6q 2918 14 administration administration NNP cord-006870-f5w6fw6q 2918 15 , , , cord-006870-f5w6fw6q 2918 16 but but CC cord-006870-f5w6fw6q 2918 17 further further JJ cord-006870-f5w6fw6q 2918 18 testing testing NN cord-006870-f5w6fw6q 2918 19 of of IN cord-006870-f5w6fw6q 2918 20 hydralazine hydralazine NN cord-006870-f5w6fw6q 2918 21 and and CC cord-006870-f5w6fw6q 2918 22 infusions infusion NNS cord-006870-f5w6fw6q 2918 23 such such JJ cord-006870-f5w6fw6q 2918 24 as as IN cord-006870-f5w6fw6q 2918 25 nicardipine nicardipine NN cord-006870-f5w6fw6q 2918 26 is be VBZ cord-006870-f5w6fw6q 2918 27 required require VBN cord-006870-f5w6fw6q 2918 28 . . . cord-006870-f5w6fw6q 2919 1 Studies study NNS cord-006870-f5w6fw6q 2919 2 exploring explore VBG cord-006870-f5w6fw6q 2919 3 correlations correlation NNS cord-006870-f5w6fw6q 2919 4 between between IN cord-006870-f5w6fw6q 2919 5 non non JJ cord-006870-f5w6fw6q 2919 6 - - JJ cord-006870-f5w6fw6q 2919 7 invasive invasive JJ cord-006870-f5w6fw6q 2919 8 ( ( -LRB- cord-006870-f5w6fw6q 2919 9 oscillometric oscillometric JJ cord-006870-f5w6fw6q 2919 10 ) ) -RRB- cord-006870-f5w6fw6q 2919 11 blood blood NN cord-006870-f5w6fw6q 2919 12 pressure pressure NN cord-006870-f5w6fw6q 2919 13 ( ( -LRB- cord-006870-f5w6fw6q 2919 14 NIBP NIBP NNP cord-006870-f5w6fw6q 2919 15 ) ) -RRB- cord-006870-f5w6fw6q 2919 16 and and CC cord-006870-f5w6fw6q 2919 17 intraarterial intraarterial JJ cord-006870-f5w6fw6q 2919 18 blood blood NN cord-006870-f5w6fw6q 2919 19 pressure pressure NN cord-006870-f5w6fw6q 2919 20 ( ( -LRB- cord-006870-f5w6fw6q 2919 21 ABP ABP NNP cord-006870-f5w6fw6q 2919 22 ) ) -RRB- cord-006870-f5w6fw6q 2919 23 have have VBP cord-006870-f5w6fw6q 2919 24 excluded exclude VBN cord-006870-f5w6fw6q 2919 25 neurocritically neurocritically RB cord-006870-f5w6fw6q 2919 26 ill ill JJ cord-006870-f5w6fw6q 2919 27 patients patient NNS cord-006870-f5w6fw6q 2919 28 with with IN cord-006870-f5w6fw6q 2919 29 continuous continuous JJ cord-006870-f5w6fw6q 2919 30 infusion infusion NN cord-006870-f5w6fw6q 2919 31 of of IN cord-006870-f5w6fw6q 2919 32 vasoactive vasoactive JJ cord-006870-f5w6fw6q 2919 33 medications medication NNS cord-006870-f5w6fw6q 2919 34 . . . cord-006870-f5w6fw6q 2920 1 Compared compare VBN cord-006870-f5w6fw6q 2920 2 to to IN cord-006870-f5w6fw6q 2920 3 ABP ABP NNP cord-006870-f5w6fw6q 2920 4 , , , cord-006870-f5w6fw6q 2920 5 NIBP NIBP NNP cord-006870-f5w6fw6q 2920 6 monitors monitor NNS cord-006870-f5w6fw6q 2920 7 generally generally RB cord-006870-f5w6fw6q 2920 8 tend tend VBP cord-006870-f5w6fw6q 2920 9 to to IN cord-006870-f5w6fw6q 2920 10 over over RB cord-006870-f5w6fw6q 2920 11 - - HYPH cord-006870-f5w6fw6q 2920 12 read read NN cord-006870-f5w6fw6q 2920 13 at at IN cord-006870-f5w6fw6q 2920 14 low low JJ cord-006870-f5w6fw6q 2920 15 values value NNS cord-006870-f5w6fw6q 2920 16 and and CC cord-006870-f5w6fw6q 2920 17 under under RB cord-006870-f5w6fw6q 2920 18 - - HYPH cord-006870-f5w6fw6q 2920 19 read read NN cord-006870-f5w6fw6q 2920 20 at at IN cord-006870-f5w6fw6q 2920 21 high high JJ cord-006870-f5w6fw6q 2920 22 values value NNS cord-006870-f5w6fw6q 2920 23 . . . cord-006870-f5w6fw6q 2921 1 This this DT cord-006870-f5w6fw6q 2921 2 study study NN cord-006870-f5w6fw6q 2921 3 examines examine VBZ cord-006870-f5w6fw6q 2921 4 the the DT cord-006870-f5w6fw6q 2921 5 relationship relationship NN cord-006870-f5w6fw6q 2921 6 between between IN cord-006870-f5w6fw6q 2921 7 simultaneously simultaneously RB cord-006870-f5w6fw6q 2921 8 measured measure VBN cord-006870-f5w6fw6q 2921 9 NIBP NIBP NNP cord-006870-f5w6fw6q 2921 10 and and CC cord-006870-f5w6fw6q 2921 11 ABP ABP NNP cord-006870-f5w6fw6q 2921 12 recordings recording NNS cord-006870-f5w6fw6q 2921 13 in in IN cord-006870-f5w6fw6q 2921 14 these these DT cord-006870-f5w6fw6q 2921 15 patients patient NNS cord-006870-f5w6fw6q 2921 16 . . . cord-006870-f5w6fw6q 2922 1 Following follow VBG cord-006870-f5w6fw6q 2922 2 informed informed JJ cord-006870-f5w6fw6q 2922 3 consent consent NN cord-006870-f5w6fw6q 2922 4 , , , cord-006870-f5w6fw6q 2922 5 prospective prospective JJ cord-006870-f5w6fw6q 2922 6 observation observation NN cord-006870-f5w6fw6q 2922 7 of of IN cord-006870-f5w6fw6q 2922 8 patients patient NNS cord-006870-f5w6fw6q 2922 9 ( ( -LRB- cord-006870-f5w6fw6q 2922 10 N=70 N=70 NNP cord-006870-f5w6fw6q 2922 11 ) ) -RRB- cord-006870-f5w6fw6q 2922 12 admitted admit VBD cord-006870-f5w6fw6q 2922 13 to to IN cord-006870-f5w6fw6q 2922 14 a a DT cord-006870-f5w6fw6q 2922 15 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 2922 16 ICU ICU NNP cord-006870-f5w6fw6q 2922 17 , , , cord-006870-f5w6fw6q 2922 18 with with IN cord-006870-f5w6fw6q 2922 19 simultaneous simultaneous JJ cord-006870-f5w6fw6q 2922 20 ABP ABP NNP cord-006870-f5w6fw6q 2922 21 and and CC cord-006870-f5w6fw6q 2922 22 NIBP NIBP NNP cord-006870-f5w6fw6q 2922 23 monitoring monitor VBG cord-006870-f5w6fw6q 2922 24 and and CC cord-006870-f5w6fw6q 2922 25 continuous continuous JJ cord-006870-f5w6fw6q 2922 26 vasopressor vasopressor NN cord-006870-f5w6fw6q 2922 27 ( ( -LRB- cord-006870-f5w6fw6q 2922 28 n=21 n=21 NNP cord-006870-f5w6fw6q 2922 29 ) ) -RRB- cord-006870-f5w6fw6q 2922 30 or or CC cord-006870-f5w6fw6q 2922 31 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 2922 32 ( ( -LRB- cord-006870-f5w6fw6q 2922 33 n=49 n=49 NNP cord-006870-f5w6fw6q 2922 34 ) ) -RRB- cord-006870-f5w6fw6q 2922 35 infusion infusion NN cord-006870-f5w6fw6q 2922 36 . . . cord-006870-f5w6fw6q 2923 1 Paired Paired NNP cord-006870-f5w6fw6q 2923 2 NIBP NIBP NNP cord-006870-f5w6fw6q 2923 3 / / SYM cord-006870-f5w6fw6q 2923 4 ABP ABP NNP cord-006870-f5w6fw6q 2923 5 observations observation NNS cord-006870-f5w6fw6q 2923 6 along along IN cord-006870-f5w6fw6q 2923 7 with with IN cord-006870-f5w6fw6q 2923 8 covariate covariate NN cord-006870-f5w6fw6q 2923 9 and and CC cord-006870-f5w6fw6q 2923 10 demographic demographic JJ cord-006870-f5w6fw6q 2923 11 data datum NNS cord-006870-f5w6fw6q 2923 12 were be VBD cord-006870-f5w6fw6q 2923 13 abstracted abstract VBN cord-006870-f5w6fw6q 2923 14 via via IN cord-006870-f5w6fw6q 2923 15 chart chart NN cord-006870-f5w6fw6q 2923 16 audit audit NN cord-006870-f5w6fw6q 2923 17 . . . cord-006870-f5w6fw6q 2924 1 Analysis analysis NN cord-006870-f5w6fw6q 2924 2 was be VBD cord-006870-f5w6fw6q 2924 3 performed perform VBN cord-006870-f5w6fw6q 2924 4 using use VBG cord-006870-f5w6fw6q 2924 5 SAS SAS NNP cord-006870-f5w6fw6q 2924 6 v9.4 v9.4 NN cord-006870-f5w6fw6q 2924 7 . . . cord-006870-f5w6fw6q 2925 1 2,177 2,177 CD cord-006870-f5w6fw6q 2925 2 paired pair VBN cord-006870-f5w6fw6q 2926 1 NIBP NIBP NNP cord-006870-f5w6fw6q 2926 2 / / SYM cord-006870-f5w6fw6q 2926 3 ABP ABP NNP cord-006870-f5w6fw6q 2926 4 observations observation NNS cord-006870-f5w6fw6q 2926 5 from from IN cord-006870-f5w6fw6q 2926 6 70 70 CD cord-006870-f5w6fw6q 2926 7 subjects subject NNS cord-006870-f5w6fw6q 2926 8 ( ( -LRB- cord-006870-f5w6fw6q 2926 9 49 49 CD cord-006870-f5w6fw6q 2926 10 % % NN cord-006870-f5w6fw6q 2926 11 male male NN cord-006870-f5w6fw6q 2926 12 , , , cord-006870-f5w6fw6q 2926 13 63 63 CD cord-006870-f5w6fw6q 2926 14 % % NN cord-006870-f5w6fw6q 2926 15 white white JJ cord-006870-f5w6fw6q 2926 16 , , , cord-006870-f5w6fw6q 2926 17 mean mean VB cord-006870-f5w6fw6q 2926 18 age age NN cord-006870-f5w6fw6q 2926 19 59 59 CD cord-006870-f5w6fw6q 2926 20 years year NNS cord-006870-f5w6fw6q 2926 21 ) ) -RRB- cord-006870-f5w6fw6q 2926 22 receiving receive VBG cord-006870-f5w6fw6q 2926 23 vasopressors vasopressor NNS cord-006870-f5w6fw6q 2926 24 ( ( -LRB- cord-006870-f5w6fw6q 2926 25 n=21 n=21 NNP cord-006870-f5w6fw6q 2926 26 ) ) -RRB- cord-006870-f5w6fw6q 2926 27 or or CC cord-006870-f5w6fw6q 2926 28 antihypertensive antihypertensive JJ cord-006870-f5w6fw6q 2926 29 agents agent NNS cord-006870-f5w6fw6q 2926 30 ( ( -LRB- cord-006870-f5w6fw6q 2926 31 n=49 n=49 NNP cord-006870-f5w6fw6q 2926 32 ) ) -RRB- cord-006870-f5w6fw6q 2926 33 . . . cord-006870-f5w6fw6q 2927 1 T T NNP cord-006870-f5w6fw6q 2927 2 - - HYPH cord-006870-f5w6fw6q 2927 3 tests test NNS cord-006870-f5w6fw6q 2927 4 show show VBP cord-006870-f5w6fw6q 2927 5 significant significant JJ cord-006870-f5w6fw6q 2927 6 difference difference NN cord-006870-f5w6fw6q 2927 7 between between IN cord-006870-f5w6fw6q 2927 8 paired paired JJ cord-006870-f5w6fw6q 2927 9 readings reading NNS cord-006870-f5w6fw6q 2927 10 : : : cord-006870-f5w6fw6q 2927 11 ( ( -LRB- cord-006870-f5w6fw6q 2927 12 [ [ -LRB- cord-006870-f5w6fw6q 2927 13 SBP SBP NNP cord-006870-f5w6fw6q 2927 14 : : : cord-006870-f5w6fw6q 2928 1 m=137 m=137 NNP cord-006870-f5w6fw6q 2928 2 vs vs IN cord-006870-f5w6fw6q 2928 3 140mmHg 140mmhg CD cord-006870-f5w6fw6q 2928 4 respectively respectively RB cord-006870-f5w6fw6q 2928 5 ; ; : cord-006870-f5w6fw6q 2928 6 p<.0001 p<.0001 NNS cord-006870-f5w6fw6q 2928 7 ] ] -RRB- cord-006870-f5w6fw6q 2928 8 , , , cord-006870-f5w6fw6q 2928 9 [ [ -LRB- cord-006870-f5w6fw6q 2928 10 DBP dbp NN cord-006870-f5w6fw6q 2928 11 : : : cord-006870-f5w6fw6q 2929 1 m=70 m=70 NNP cord-006870-f5w6fw6q 2930 1 vs vs IN cord-006870-f5w6fw6q 2930 2 68mmHg 68mmhg CD cord-006870-f5w6fw6q 2930 3 respectively respectively RB cord-006870-f5w6fw6q 2930 4 , , , cord-006870-f5w6fw6q 2930 5 p<.0001 p<.0001 NNS cord-006870-f5w6fw6q 2930 6 ] ] -RRB- cord-006870-f5w6fw6q 2930 7 , , , cord-006870-f5w6fw6q 2930 8 [ [ -LRB- cord-006870-f5w6fw6q 2930 9 MAP map NN cord-006870-f5w6fw6q 2930 10 : : : cord-006870-f5w6fw6q 2931 1 m=86 m=86 NNP cord-006870-f5w6fw6q 2932 1 vs vs IN cord-006870-f5w6fw6q 2932 2 m=90mmHg m=90mmHg NNP cord-006870-f5w6fw6q 2932 3 respectively respectively RB cord-006870-f5w6fw6q 2932 4 , , , cord-006870-f5w6fw6q 2932 5 p<.0001 p<.0001 NNS cord-006870-f5w6fw6q 2932 6 ] ] -RRB- cord-006870-f5w6fw6q 2932 7 ) ) -RRB- cord-006870-f5w6fw6q 2932 8 . . . cord-006870-f5w6fw6q 2933 1 The the DT cord-006870-f5w6fw6q 2933 2 paired paired JJ cord-006870-f5w6fw6q 2933 3 differences difference NNS cord-006870-f5w6fw6q 2933 4 for for IN cord-006870-f5w6fw6q 2933 5 specific specific JJ cord-006870-f5w6fw6q 2933 6 medications medication NNS cord-006870-f5w6fw6q 2933 7 were be VBD cord-006870-f5w6fw6q 2933 8 tabulated tabulate VBN cord-006870-f5w6fw6q 2933 9 , , , cord-006870-f5w6fw6q 2933 10 with with IN cord-006870-f5w6fw6q 2933 11 50 50 CD cord-006870-f5w6fw6q 2933 12 - - SYM cord-006870-f5w6fw6q 2933 13 70 70 CD cord-006870-f5w6fw6q 2933 14 % % NN cord-006870-f5w6fw6q 2933 15 of of IN cord-006870-f5w6fw6q 2933 16 the the DT cord-006870-f5w6fw6q 2933 17 differences difference NNS cord-006870-f5w6fw6q 2933 18 < < XX cord-006870-f5w6fw6q 2933 19 10mmHg 10mmhg CD cord-006870-f5w6fw6q 2933 20 , , , cord-006870-f5w6fw6q 2933 21 and and CC cord-006870-f5w6fw6q 2933 22 75 75 CD cord-006870-f5w6fw6q 2933 23 - - SYM cord-006870-f5w6fw6q 2933 24 90 90 CD cord-006870-f5w6fw6q 2933 25 % % NN cord-006870-f5w6fw6q 2933 26 of of IN cord-006870-f5w6fw6q 2933 27 the the DT cord-006870-f5w6fw6q 2933 28 values value NNS cord-006870-f5w6fw6q 2933 29 with with IN cord-006870-f5w6fw6q 2933 30 < < XX cord-006870-f5w6fw6q 2933 31 20mmHg 20mmhg CD cord-006870-f5w6fw6q 2933 32 difference difference NN cord-006870-f5w6fw6q 2933 33 . . . cord-006870-f5w6fw6q 2934 1 Bland Bland NNP cord-006870-f5w6fw6q 2934 2 - - HYPH cord-006870-f5w6fw6q 2934 3 Altman Altman NNP cord-006870-f5w6fw6q 2934 4 plots plot NNS cord-006870-f5w6fw6q 2934 5 for for IN cord-006870-f5w6fw6q 2934 6 MAP MAP NNP cord-006870-f5w6fw6q 2934 7 , , , cord-006870-f5w6fw6q 2934 8 SBP SBP NNP cord-006870-f5w6fw6q 2934 9 , , , cord-006870-f5w6fw6q 2934 10 and and CC cord-006870-f5w6fw6q 2935 1 DBP DBP NNP cord-006870-f5w6fw6q 2935 2 demonstrate demonstrate VBP cord-006870-f5w6fw6q 2935 3 good good JJ cord-006870-f5w6fw6q 2935 4 intermethod intermethod NN cord-006870-f5w6fw6q 2935 5 agreement agreement NN cord-006870-f5w6fw6q 2935 6 between between IN cord-006870-f5w6fw6q 2935 7 paired pair VBN cord-006870-f5w6fw6q 2935 8 measures measure NNS cord-006870-f5w6fw6q 2935 9 ( ( -LRB- cord-006870-f5w6fw6q 2935 10 excluding exclude VBG cord-006870-f5w6fw6q 2935 11 outliers outlier NNS cord-006870-f5w6fw6q 2935 12 ) ) -RRB- cord-006870-f5w6fw6q 2935 13 and and CC cord-006870-f5w6fw6q 2935 14 demonstrated demonstrate VBD cord-006870-f5w6fw6q 2935 15 marked mark VBN cord-006870-f5w6fw6q 2935 16 NIBP NIBP NNP cord-006870-f5w6fw6q 2935 17 - - HYPH cord-006870-f5w6fw6q 2935 18 ABP ABP NNP cord-006870-f5w6fw6q 2935 19 SBP SBP NNP cord-006870-f5w6fw6q 2935 20 differences difference NNS cord-006870-f5w6fw6q 2935 21 at at IN cord-006870-f5w6fw6q 2935 22 higher high JJR cord-006870-f5w6fw6q 2935 23 blood blood NN cord-006870-f5w6fw6q 2935 24 pressures pressure NNS cord-006870-f5w6fw6q 2935 25 . . . cord-006870-f5w6fw6q 2936 1 Pearson Pearson NNP cord-006870-f5w6fw6q 2936 2 Correlation Correlation NNP cord-006870-f5w6fw6q 2936 3 Coefficients Coefficients NNP cord-006870-f5w6fw6q 2936 4 for for IN cord-006870-f5w6fw6q 2936 5 paired pair VBN cord-006870-f5w6fw6q 2936 6 measurements measurement NNS cord-006870-f5w6fw6q 2936 7 show show VBP cord-006870-f5w6fw6q 2936 8 strong strong JJ cord-006870-f5w6fw6q 2936 9 positive positive JJ cord-006870-f5w6fw6q 2936 10 correlation correlation NN cord-006870-f5w6fw6q 2936 11 for for IN cord-006870-f5w6fw6q 2936 12 MAP MAP NNP cord-006870-f5w6fw6q 2936 13 ( ( -LRB- cord-006870-f5w6fw6q 2936 14 +0.82 +0.82 NNP cord-006870-f5w6fw6q 2936 15 ) ) -RRB- cord-006870-f5w6fw6q 2936 16 , , , cord-006870-f5w6fw6q 2936 17 SBP SBP NNP cord-006870-f5w6fw6q 2936 18 ( ( -LRB- cord-006870-f5w6fw6q 2936 19 +0.84 +0.84 NNP cord-006870-f5w6fw6q 2936 20 ) ) -RRB- cord-006870-f5w6fw6q 2936 21 , , , cord-006870-f5w6fw6q 2936 22 and and CC cord-006870-f5w6fw6q 2936 23 DBP DBP NNP cord-006870-f5w6fw6q 2936 24 ( ( -LRB- cord-006870-f5w6fw6q 2936 25 +0.73 +0.73 NNP cord-006870-f5w6fw6q 2936 26 ) ) -RRB- cord-006870-f5w6fw6q 2936 27 . . . cord-006870-f5w6fw6q 2937 1 Despite despite IN cord-006870-f5w6fw6q 2937 2 a a DT cord-006870-f5w6fw6q 2937 3 statistically statistically RB cord-006870-f5w6fw6q 2937 4 significant significant JJ cord-006870-f5w6fw6q 2937 5 difference difference NN cord-006870-f5w6fw6q 2937 6 between between IN cord-006870-f5w6fw6q 2937 7 NIBP NIBP NNP cord-006870-f5w6fw6q 2937 8 and and CC cord-006870-f5w6fw6q 2937 9 ABP ABP NNP cord-006870-f5w6fw6q 2937 10 readings reading NNS cord-006870-f5w6fw6q 2937 11 for for IN cord-006870-f5w6fw6q 2937 12 patients patient NNS cord-006870-f5w6fw6q 2937 13 on on IN cord-006870-f5w6fw6q 2937 14 vasoactive vasoactive JJ cord-006870-f5w6fw6q 2937 15 medications medication NNS cord-006870-f5w6fw6q 2937 16 , , , cord-006870-f5w6fw6q 2937 17 there there EX cord-006870-f5w6fw6q 2937 18 may may MD cord-006870-f5w6fw6q 2937 19 be be VB cord-006870-f5w6fw6q 2937 20 no no DT cord-006870-f5w6fw6q 2937 21 clinical clinical JJ cord-006870-f5w6fw6q 2937 22 significance significance NN cord-006870-f5w6fw6q 2937 23 . . . cord-006870-f5w6fw6q 2938 1 The the DT cord-006870-f5w6fw6q 2938 2 relatively relatively RB cord-006870-f5w6fw6q 2938 3 positive positive JJ cord-006870-f5w6fw6q 2938 4 and and CC cord-006870-f5w6fw6q 2938 5 linear linear JJ cord-006870-f5w6fw6q 2938 6 correlation correlation NN cord-006870-f5w6fw6q 2938 7 between between IN cord-006870-f5w6fw6q 2938 8 paired paired JJ cord-006870-f5w6fw6q 2938 9 values value NNS cord-006870-f5w6fw6q 2938 10 guide guide VB cord-006870-f5w6fw6q 2938 11 providers provider NNS cord-006870-f5w6fw6q 2938 12 towards towards IN cord-006870-f5w6fw6q 2938 13 not not RB cord-006870-f5w6fw6q 2938 14 being be VBG cord-006870-f5w6fw6q 2938 15 forced force VBN cord-006870-f5w6fw6q 2938 16 to to TO cord-006870-f5w6fw6q 2938 17 use use VB cord-006870-f5w6fw6q 2938 18 one one NN cord-006870-f5w6fw6q 2938 19 over over IN cord-006870-f5w6fw6q 2938 20 the the DT cord-006870-f5w6fw6q 2938 21 other other JJ cord-006870-f5w6fw6q 2938 22 . . . cord-006870-f5w6fw6q 2939 1 The the DT cord-006870-f5w6fw6q 2939 2 final final JJ cord-006870-f5w6fw6q 2939 3 manuscript manuscript NN cord-006870-f5w6fw6q 2939 4 will will MD cord-006870-f5w6fw6q 2939 5 aim aim VB cord-006870-f5w6fw6q 2939 6 to to TO cord-006870-f5w6fw6q 2939 7 detail detail VB cord-006870-f5w6fw6q 2939 8 whether whether IN cord-006870-f5w6fw6q 2939 9 there there EX cord-006870-f5w6fw6q 2939 10 is be VBZ cord-006870-f5w6fw6q 2939 11 a a DT cord-006870-f5w6fw6q 2939 12 clinical clinical JJ cord-006870-f5w6fw6q 2939 13 significance significance NN cord-006870-f5w6fw6q 2939 14 in in IN cord-006870-f5w6fw6q 2939 15 particular particular JJ cord-006870-f5w6fw6q 2939 16 vasoactive vasoactive JJ cord-006870-f5w6fw6q 2939 17 medications medication NNS cord-006870-f5w6fw6q 2939 18 . . . cord-006870-f5w6fw6q 2940 1 Pathological pathological JJ cord-006870-f5w6fw6q 2940 2 activity activity NN cord-006870-f5w6fw6q 2940 3 in in IN cord-006870-f5w6fw6q 2940 4 continuous continuous JJ cord-006870-f5w6fw6q 2940 5 electroencephalogram electroencephalogram NN cord-006870-f5w6fw6q 2940 6 ( ( -LRB- cord-006870-f5w6fw6q 2941 1 cEEG ceeg LS cord-006870-f5w6fw6q 2941 2 ) ) -RRB- cord-006870-f5w6fw6q 2941 3 data datum NNS cord-006870-f5w6fw6q 2941 4 of of IN cord-006870-f5w6fw6q 2941 5 ICU ICU NNP cord-006870-f5w6fw6q 2941 6 patients patient NNS cord-006870-f5w6fw6q 2941 7 is be VBZ cord-006870-f5w6fw6q 2941 8 conventionally conventionally RB cord-006870-f5w6fw6q 2941 9 categorized categorize VBN cord-006870-f5w6fw6q 2941 10 into into IN cord-006870-f5w6fw6q 2941 11 a a DT cord-006870-f5w6fw6q 2941 12 small small JJ cord-006870-f5w6fw6q 2941 13 number number NN cord-006870-f5w6fw6q 2941 14 of of IN cord-006870-f5w6fw6q 2941 15 named name VBN cord-006870-f5w6fw6q 2941 16 rhythmic rhythmic JJ cord-006870-f5w6fw6q 2941 17 and and CC cord-006870-f5w6fw6q 2941 18 periodic periodic JJ cord-006870-f5w6fw6q 2941 19 patterns pattern NNS cord-006870-f5w6fw6q 2941 20 . . . cord-006870-f5w6fw6q 2942 1 We -PRON- PRP cord-006870-f5w6fw6q 2942 2 aimed aim VBD cord-006870-f5w6fw6q 2942 3 to to TO cord-006870-f5w6fw6q 2942 4 develop develop VB cord-006870-f5w6fw6q 2942 5 a a DT cord-006870-f5w6fw6q 2942 6 valid valid JJ cord-006870-f5w6fw6q 2942 7 method method NN cord-006870-f5w6fw6q 2942 8 to to TO cord-006870-f5w6fw6q 2942 9 automatically automatically RB cord-006870-f5w6fw6q 2942 10 discover discover VB cord-006870-f5w6fw6q 2942 11 a a DT cord-006870-f5w6fw6q 2942 12 small small JJ cord-006870-f5w6fw6q 2942 13 number number NN cord-006870-f5w6fw6q 2942 14 of of IN cord-006870-f5w6fw6q 2942 15 homogeneous homogeneous JJ cord-006870-f5w6fw6q 2942 16 pattern pattern NN cord-006870-f5w6fw6q 2942 17 clusters cluster NNS cord-006870-f5w6fw6q 2942 18 , , , cord-006870-f5w6fw6q 2942 19 to to TO cord-006870-f5w6fw6q 2942 20 facilitate facilitate VB cord-006870-f5w6fw6q 2942 21 efficient efficient JJ cord-006870-f5w6fw6q 2942 22 interactive interactive JJ cord-006870-f5w6fw6q 2942 23 labeling labeling NN cord-006870-f5w6fw6q 2942 24 by by IN cord-006870-f5w6fw6q 2942 25 cEEG ceeg NN cord-006870-f5w6fw6q 2942 26 experts expert NNS cord-006870-f5w6fw6q 2942 27 . . . cord-006870-f5w6fw6q 2943 1 We -PRON- PRP cord-006870-f5w6fw6q 2943 2 extracted extract VBD cord-006870-f5w6fw6q 2943 3 576 576 CD cord-006870-f5w6fw6q 2943 4 time time NN cord-006870-f5w6fw6q 2943 5 and and CC cord-006870-f5w6fw6q 2943 6 frequency frequency NN cord-006870-f5w6fw6q 2943 7 domain domain NN cord-006870-f5w6fw6q 2943 8 features feature VBZ cord-006870-f5w6fw6q 2943 9 from from IN cord-006870-f5w6fw6q 2943 10 12 12 CD cord-006870-f5w6fw6q 2943 11 + + CD cord-006870-f5w6fw6q 2943 12 hour hour NN cord-006870-f5w6fw6q 2943 13 cEEG ceeg NN cord-006870-f5w6fw6q 2943 14 recordings recording NNS cord-006870-f5w6fw6q 2943 15 from from IN cord-006870-f5w6fw6q 2943 16 10 10 CD cord-006870-f5w6fw6q 2943 17 different different JJ cord-006870-f5w6fw6q 2943 18 ICU ICU NNP cord-006870-f5w6fw6q 2943 19 patients patient NNS cord-006870-f5w6fw6q 2943 20 . . . cord-006870-f5w6fw6q 2944 1 After after IN cord-006870-f5w6fw6q 2944 2 removing remove VBG cord-006870-f5w6fw6q 2944 3 artifacts artifact NNS cord-006870-f5w6fw6q 2944 4 , , , cord-006870-f5w6fw6q 2944 5 we -PRON- PRP cord-006870-f5w6fw6q 2944 6 applied apply VBD cord-006870-f5w6fw6q 2944 7 principal principal JJ cord-006870-f5w6fw6q 2944 8 component component NN cord-006870-f5w6fw6q 2944 9 analysis analysis NN cord-006870-f5w6fw6q 2944 10 ( ( -LRB- cord-006870-f5w6fw6q 2944 11 90 90 CD cord-006870-f5w6fw6q 2944 12 % % NN cord-006870-f5w6fw6q 2944 13 variance variance NN cord-006870-f5w6fw6q 2944 14 retained retain VBN cord-006870-f5w6fw6q 2944 15 ) ) -RRB- cord-006870-f5w6fw6q 2944 16 , , , cord-006870-f5w6fw6q 2944 17 then then RB cord-006870-f5w6fw6q 2944 18 separated separate VBD cord-006870-f5w6fw6q 2944 19 the the DT cord-006870-f5w6fw6q 2944 20 data datum NNS cord-006870-f5w6fw6q 2944 21 into into IN cord-006870-f5w6fw6q 2944 22 9 9 CD cord-006870-f5w6fw6q 2944 23 clusters cluster NNS cord-006870-f5w6fw6q 2944 24 ( ( -LRB- cord-006870-f5w6fw6q 2944 25 K k NN cord-006870-f5w6fw6q 2944 26 - - HYPH cord-006870-f5w6fw6q 2944 27 means mean NNS cord-006870-f5w6fw6q 2944 28 ) ) -RRB- cord-006870-f5w6fw6q 2944 29 . . . cord-006870-f5w6fw6q 2945 1 From from IN cord-006870-f5w6fw6q 2945 2 each each DT cord-006870-f5w6fw6q 2945 3 cluster cluster NN cord-006870-f5w6fw6q 2945 4 we -PRON- PRP cord-006870-f5w6fw6q 2945 5 took take VBD cord-006870-f5w6fw6q 2945 6 9 9 CD cord-006870-f5w6fw6q 2945 7 random random JJ cord-006870-f5w6fw6q 2945 8 samples sample NNS cord-006870-f5w6fw6q 2945 9 plus plus CC cord-006870-f5w6fw6q 2945 10 the the DT cord-006870-f5w6fw6q 2945 11 most most RBS cord-006870-f5w6fw6q 2945 12 central central JJ cord-006870-f5w6fw6q 2945 13 one one NN cord-006870-f5w6fw6q 2945 14 , , , cord-006870-f5w6fw6q 2945 15 rendering render VBG cord-006870-f5w6fw6q 2945 16 900 900 CD cord-006870-f5w6fw6q 2945 17 samples sample NNS cord-006870-f5w6fw6q 2945 18 in in IN cord-006870-f5w6fw6q 2945 19 total total NN cord-006870-f5w6fw6q 2945 20 . . . cord-006870-f5w6fw6q 2946 1 Three three CD cord-006870-f5w6fw6q 2946 2 expert expert NN cord-006870-f5w6fw6q 2946 3 electroencephalographers electroencephalographer NNS cord-006870-f5w6fw6q 2946 4 independently independently RB cord-006870-f5w6fw6q 2946 5 categorized categorize VBD cord-006870-f5w6fw6q 2946 6 all all DT cord-006870-f5w6fw6q 2946 7 samples sample NNS cord-006870-f5w6fw6q 2946 8 into into IN cord-006870-f5w6fw6q 2946 9 one one CD cord-006870-f5w6fw6q 2946 10 of of IN cord-006870-f5w6fw6q 2946 11 6 6 CD cord-006870-f5w6fw6q 2946 12 standard standard JJ cord-006870-f5w6fw6q 2946 13 pattern pattern NN cord-006870-f5w6fw6q 2946 14 categories category NNS cord-006870-f5w6fw6q 2946 15 ( ( -LRB- cord-006870-f5w6fw6q 2946 16 seizures seizure NNS cord-006870-f5w6fw6q 2946 17 , , , cord-006870-f5w6fw6q 2946 18 GPDs gpd NNS cord-006870-f5w6fw6q 2946 19 , , , cord-006870-f5w6fw6q 2946 20 LPDs lpd NNS cord-006870-f5w6fw6q 2946 21 , , , cord-006870-f5w6fw6q 2946 22 LRDA LRDA NNP cord-006870-f5w6fw6q 2946 23 , , , cord-006870-f5w6fw6q 2946 24 GRDA GRDA NNP cord-006870-f5w6fw6q 2946 25 , , , cord-006870-f5w6fw6q 2946 26 burst burst VBD cord-006870-f5w6fw6q 2946 27 suppression suppression NN cord-006870-f5w6fw6q 2946 28 , , , cord-006870-f5w6fw6q 2946 29 other other JJ cord-006870-f5w6fw6q 2946 30 ) ) -RRB- cord-006870-f5w6fw6q 2946 31 . . . cord-006870-f5w6fw6q 2947 1 We -PRON- PRP cord-006870-f5w6fw6q 2947 2 compared compare VBD cord-006870-f5w6fw6q 2947 3 two two CD cord-006870-f5w6fw6q 2947 4 methods method NNS cord-006870-f5w6fw6q 2947 5 for for IN cord-006870-f5w6fw6q 2947 6 labeling labeling NN cord-006870-f5w6fw6q 2947 7 clusters cluster NNS cord-006870-f5w6fw6q 2947 8 : : : cord-006870-f5w6fw6q 2947 9 ( ( -LRB- cord-006870-f5w6fw6q 2947 10 1 1 LS cord-006870-f5w6fw6q 2947 11 ) ) -RRB- cord-006870-f5w6fw6q 2947 12 " " `` cord-006870-f5w6fw6q 2947 13 Labor labor NN cord-006870-f5w6fw6q 2947 14 intensive intensive JJ cord-006870-f5w6fw6q 2947 15 labeling labeling NN cord-006870-f5w6fw6q 2947 16 " " '' cord-006870-f5w6fw6q 2947 17 ( ( -LRB- cord-006870-f5w6fw6q 2947 18 LIL LIL NNP cord-006870-f5w6fw6q 2947 19 ) ) -RRB- cord-006870-f5w6fw6q 2947 20 : : : cord-006870-f5w6fw6q 2947 21 assign assign VB cord-006870-f5w6fw6q 2947 22 the the DT cord-006870-f5w6fw6q 2947 23 most most RBS cord-006870-f5w6fw6q 2947 24 frequent frequent JJ cord-006870-f5w6fw6q 2947 25 of of IN cord-006870-f5w6fw6q 2947 26 30 30 CD cord-006870-f5w6fw6q 2947 27 expert expert NN cord-006870-f5w6fw6q 2947 28 - - HYPH cord-006870-f5w6fw6q 2947 29 provided provide VBN cord-006870-f5w6fw6q 2947 30 labels label NNS cord-006870-f5w6fw6q 2947 31 ; ; , cord-006870-f5w6fw6q 2947 32 ( ( -LRB- cord-006870-f5w6fw6q 2947 33 2 2 LS cord-006870-f5w6fw6q 2947 34 ) ) -RRB- cord-006870-f5w6fw6q 2947 35 " " `` cord-006870-f5w6fw6q 2947 36 Labor labor NN cord-006870-f5w6fw6q 2947 37 efficient efficient JJ cord-006870-f5w6fw6q 2947 38 labeling labeling NN cord-006870-f5w6fw6q 2947 39 " " '' cord-006870-f5w6fw6q 2947 40 ( ( -LRB- cord-006870-f5w6fw6q 2947 41 LEL LEL NNP cord-006870-f5w6fw6q 2947 42 ) ) -RRB- cord-006870-f5w6fw6q 2947 43 : : : cord-006870-f5w6fw6q 2947 44 assign assign VB cord-006870-f5w6fw6q 2947 45 the the DT cord-006870-f5w6fw6q 2947 46 most most RBS cord-006870-f5w6fw6q 2947 47 frequent frequent JJ cord-006870-f5w6fw6q 2947 48 of of IN cord-006870-f5w6fw6q 2947 49 the the DT cord-006870-f5w6fw6q 2947 50 3 3 CD cord-006870-f5w6fw6q 2947 51 expert expert NN cord-006870-f5w6fw6q 2947 52 labels label NNS cord-006870-f5w6fw6q 2947 53 for for IN cord-006870-f5w6fw6q 2947 54 the the DT cord-006870-f5w6fw6q 2947 55 central central JJ cord-006870-f5w6fw6q 2947 56 sample sample NN cord-006870-f5w6fw6q 2947 57 . . . cord-006870-f5w6fw6q 2948 1 We -PRON- PRP cord-006870-f5w6fw6q 2948 2 compared compare VBD cord-006870-f5w6fw6q 2948 3 interrater interrater NN cord-006870-f5w6fw6q 2948 4 agreement agreement NN cord-006870-f5w6fw6q 2948 5 ( ( -LRB- cord-006870-f5w6fw6q 2948 6 IRA IRA NNP cord-006870-f5w6fw6q 2948 7 ) ) -RRB- cord-006870-f5w6fw6q 2948 8 among among IN cord-006870-f5w6fw6q 2948 9 experts expert NNS cord-006870-f5w6fw6q 2948 10 vs. vs. FW cord-006870-f5w6fw6q 2948 11 between between IN cord-006870-f5w6fw6q 2948 12 each each DT cord-006870-f5w6fw6q 2948 13 expert expert NN cord-006870-f5w6fw6q 2948 14 and and CC cord-006870-f5w6fw6q 2948 15 consensus consensus NN cord-006870-f5w6fw6q 2948 16 labels label NNS cord-006870-f5w6fw6q 2948 17 using use VBG cord-006870-f5w6fw6q 2948 18 LIL LIL NNP cord-006870-f5w6fw6q 2948 19 vs. vs. IN cord-006870-f5w6fw6q 2948 20 LEL LEL NNP cord-006870-f5w6fw6q 2948 21 . . . cord-006870-f5w6fw6q 2949 1 Finally finally RB cord-006870-f5w6fw6q 2949 2 , , , cord-006870-f5w6fw6q 2949 3 we -PRON- PRP cord-006870-f5w6fw6q 2949 4 used use VBD cord-006870-f5w6fw6q 2949 5 Laplacian Laplacian NNP cord-006870-f5w6fw6q 2949 6 Eigenmaps Eigenmaps NNP cord-006870-f5w6fw6q 2949 7 ( ( -LRB- cord-006870-f5w6fw6q 2949 8 LE LE NNP cord-006870-f5w6fw6q 2949 9 ) ) -RRB- cord-006870-f5w6fw6q 2949 10 to to TO cord-006870-f5w6fw6q 2949 11 visualize visualize VB cord-006870-f5w6fw6q 2949 12 the the DT cord-006870-f5w6fw6q 2949 13 data datum NNS cord-006870-f5w6fw6q 2949 14 . . . cord-006870-f5w6fw6q 2949 15 _SP cord-006870-f5w6fw6q 2950 1 This this DT cord-006870-f5w6fw6q 2950 2 research research NN cord-006870-f5w6fw6q 2950 3 suggests suggest VBZ cord-006870-f5w6fw6q 2950 4 that that IN cord-006870-f5w6fw6q 2950 5 large large JJ cord-006870-f5w6fw6q 2950 6 cEEG ceeg NN cord-006870-f5w6fw6q 2950 7 datasets dataset NNS cord-006870-f5w6fw6q 2950 8 can can MD cord-006870-f5w6fw6q 2950 9 be be VB cord-006870-f5w6fw6q 2950 10 automatically automatically RB cord-006870-f5w6fw6q 2950 11 clustered cluster VBN cord-006870-f5w6fw6q 2950 12 into into IN cord-006870-f5w6fw6q 2950 13 a a DT cord-006870-f5w6fw6q 2950 14 small small JJ cord-006870-f5w6fw6q 2950 15 number number NN cord-006870-f5w6fw6q 2950 16 of of IN cord-006870-f5w6fw6q 2950 17 patterns pattern NNS cord-006870-f5w6fw6q 2950 18 described describe VBN cord-006870-f5w6fw6q 2950 19 by by IN cord-006870-f5w6fw6q 2950 20 standard standard JJ cord-006870-f5w6fw6q 2950 21 ICU ICU NNP cord-006870-f5w6fw6q 2950 22 EEG EEG NNP cord-006870-f5w6fw6q 2950 23 pattern pattern NN cord-006870-f5w6fw6q 2950 24 labels label NNS cord-006870-f5w6fw6q 2950 25 . . . cord-006870-f5w6fw6q 2951 1 We -PRON- PRP cord-006870-f5w6fw6q 2951 2 demonstrated demonstrate VBD cord-006870-f5w6fw6q 2951 3 efficient efficient JJ cord-006870-f5w6fw6q 2951 4 cluster cluster NN cord-006870-f5w6fw6q 2951 5 labeling labeling NN cord-006870-f5w6fw6q 2951 6 by by IN cord-006870-f5w6fw6q 2951 7 inspecting inspect VBG cord-006870-f5w6fw6q 2951 8 only only RB cord-006870-f5w6fw6q 2951 9 the the DT cord-006870-f5w6fw6q 2951 10 central central RB cord-006870-f5w6fw6q 2951 11 - - HYPH cord-006870-f5w6fw6q 2951 12 most most JJS cord-006870-f5w6fw6q 2951 13 representative representative NN cord-006870-f5w6fw6q 2951 14 of of IN cord-006870-f5w6fw6q 2951 15 each each DT cord-006870-f5w6fw6q 2951 16 cluster cluster NN cord-006870-f5w6fw6q 2951 17 . . . cord-006870-f5w6fw6q 2952 1 Furthermore furthermore RB cord-006870-f5w6fw6q 2952 2 , , , cord-006870-f5w6fw6q 2952 3 LE LE NNP cord-006870-f5w6fw6q 2952 4 visualizations visualization NNS cord-006870-f5w6fw6q 2952 5 support support VBP cord-006870-f5w6fw6q 2952 6 the the DT cord-006870-f5w6fw6q 2952 7 hypothesis hypothesis NN cord-006870-f5w6fw6q 2952 8 of of IN cord-006870-f5w6fw6q 2952 9 an an DT cord-006870-f5w6fw6q 2952 10 interictal interictal JJ cord-006870-f5w6fw6q 2952 11 - - HYPH cord-006870-f5w6fw6q 2952 12 ictal ictal JJ cord-006870-f5w6fw6q 2952 13 continuum continuum NN cord-006870-f5w6fw6q 2952 14 . . . cord-006870-f5w6fw6q 2953 1 Real real JJ cord-006870-f5w6fw6q 2953 2 time time NN cord-006870-f5w6fw6q 2953 3 measurement measurement NN cord-006870-f5w6fw6q 2953 4 of of IN cord-006870-f5w6fw6q 2953 5 cerebral cerebral NNP cord-006870-f5w6fw6q 2953 6 oxyhemoglobin oxyhemoglobin NNP cord-006870-f5w6fw6q 2953 7 ( ( -LRB- cord-006870-f5w6fw6q 2953 8 OxyHb OxyHb NNP cord-006870-f5w6fw6q 2953 9 ) ) -RRB- cord-006870-f5w6fw6q 2953 10 and and CC cord-006870-f5w6fw6q 2953 11 deoxyhemoglobin deoxyhemoglobin NNP cord-006870-f5w6fw6q 2953 12 ( ( -LRB- cord-006870-f5w6fw6q 2953 13 DeoxyHb DeoxyHb NNP cord-006870-f5w6fw6q 2953 14 ) ) -RRB- cord-006870-f5w6fw6q 2953 15 using use VBG cord-006870-f5w6fw6q 2953 16 near near IN cord-006870-f5w6fw6q 2953 17 infrared infrared JJ cord-006870-f5w6fw6q 2953 18 spectroscopy spectroscopy NN cord-006870-f5w6fw6q 2953 19 ( ( -LRB- cord-006870-f5w6fw6q 2953 20 NIRS NIRS NNP cord-006870-f5w6fw6q 2953 21 ) ) -RRB- cord-006870-f5w6fw6q 2953 22 may may MD cord-006870-f5w6fw6q 2953 23 help help VB cord-006870-f5w6fw6q 2953 24 us -PRON- PRP cord-006870-f5w6fw6q 2953 25 better well RBR cord-006870-f5w6fw6q 2953 26 understand understand VB cord-006870-f5w6fw6q 2953 27 the the DT cord-006870-f5w6fw6q 2953 28 status status NN cord-006870-f5w6fw6q 2953 29 of of IN cord-006870-f5w6fw6q 2953 30 cerebral cerebral JJ cord-006870-f5w6fw6q 2953 31 oxygenation oxygenation NN cord-006870-f5w6fw6q 2953 32 and and CC cord-006870-f5w6fw6q 2953 33 possibly possibly RB cord-006870-f5w6fw6q 2953 34 cerebral cerebral JJ cord-006870-f5w6fw6q 2953 35 blood blood NN cord-006870-f5w6fw6q 2953 36 flow flow NN cord-006870-f5w6fw6q 2953 37 ( ( -LRB- cord-006870-f5w6fw6q 2953 38 CBF CBF NNP cord-006870-f5w6fw6q 2953 39 ) ) -RRB- cord-006870-f5w6fw6q 2953 40 in in IN cord-006870-f5w6fw6q 2953 41 patients patient NNS cord-006870-f5w6fw6q 2953 42 with with IN cord-006870-f5w6fw6q 2953 43 acute acute JJ cord-006870-f5w6fw6q 2953 44 brain brain NN cord-006870-f5w6fw6q 2953 45 injury injury NN cord-006870-f5w6fw6q 2953 46 . . . cord-006870-f5w6fw6q 2954 1 We -PRON- PRP cord-006870-f5w6fw6q 2954 2 developed develop VBD cord-006870-f5w6fw6q 2954 3 48 48 CD cord-006870-f5w6fw6q 2954 4 multichannel multichannel JJ cord-006870-f5w6fw6q 2954 5 functional functional JJ cord-006870-f5w6fw6q 2954 6 NIRS NIRS NNP cord-006870-f5w6fw6q 2954 7 ( ( -LRB- cord-006870-f5w6fw6q 2954 8 fNIRS fnirs NN cord-006870-f5w6fw6q 2954 9 ) ) -RRB- cord-006870-f5w6fw6q 2954 10 system system NN cord-006870-f5w6fw6q 2954 11 and and CC cord-006870-f5w6fw6q 2954 12 evaluated evaluate VBD cord-006870-f5w6fw6q 2954 13 its -PRON- PRP$ cord-006870-f5w6fw6q 2954 14 role role NN cord-006870-f5w6fw6q 2954 15 in in IN cord-006870-f5w6fw6q 2954 16 patients patient NNS cord-006870-f5w6fw6q 2954 17 with with IN cord-006870-f5w6fw6q 2954 18 acute acute JJ cord-006870-f5w6fw6q 2954 19 brain brain NN cord-006870-f5w6fw6q 2954 20 injury injury NN cord-006870-f5w6fw6q 2954 21 . . . cord-006870-f5w6fw6q 2955 1 A a DT cord-006870-f5w6fw6q 2955 2 48 48 CD cord-006870-f5w6fw6q 2955 3 Channel Channel NNP cord-006870-f5w6fw6q 2955 4 fNIRS fnirs NN cord-006870-f5w6fw6q 2955 5 system system NN cord-006870-f5w6fw6q 2955 6 ( ( -LRB- cord-006870-f5w6fw6q 2955 7 NIRSITTM NIRSITTM NNP cord-006870-f5w6fw6q 2955 8 ) ) -RRB- cord-006870-f5w6fw6q 2955 9 was be VBD cord-006870-f5w6fw6q 2955 10 used use VBN cord-006870-f5w6fw6q 2955 11 for for IN cord-006870-f5w6fw6q 2955 12 measuring measure VBG cord-006870-f5w6fw6q 2955 13 cerebral cerebral NNP cord-006870-f5w6fw6q 2955 14 OxyHb OxyHb NNP cord-006870-f5w6fw6q 2955 15 and and CC cord-006870-f5w6fw6q 2955 16 DeoxyHb DeoxyHb NNP cord-006870-f5w6fw6q 2955 17 in in IN cord-006870-f5w6fw6q 2955 18 patients patient NNS cord-006870-f5w6fw6q 2955 19 with with IN cord-006870-f5w6fw6q 2955 20 brain brain NN cord-006870-f5w6fw6q 2955 21 injury injury NN cord-006870-f5w6fw6q 2955 22 . . . cord-006870-f5w6fw6q 2956 1 Measurement measurement NN cord-006870-f5w6fw6q 2956 2 protocols protocol NNS cord-006870-f5w6fw6q 2956 3 were be VBD cord-006870-f5w6fw6q 2956 4 as as IN cord-006870-f5w6fw6q 2956 5 follows follow VBZ cord-006870-f5w6fw6q 2956 6 ; ; : cord-006870-f5w6fw6q 2956 7 baseline baseline JJ cord-006870-f5w6fw6q 2956 8 measurement measurement NN cord-006870-f5w6fw6q 2956 9 for for IN cord-006870-f5w6fw6q 2956 10 5 5 CD cord-006870-f5w6fw6q 2956 11 minutes minute NNS cord-006870-f5w6fw6q 2956 12 with with IN cord-006870-f5w6fw6q 2956 13 activation activation NN cord-006870-f5w6fw6q 2956 14 stimuli stimulus NNS cord-006870-f5w6fw6q 2956 15 ( ( -LRB- cord-006870-f5w6fw6q 2956 16 nipple nipple NN cord-006870-f5w6fw6q 2956 17 pinching pinch VBG cord-006870-f5w6fw6q 2956 18 for for IN cord-006870-f5w6fw6q 2956 19 5 5 CD cord-006870-f5w6fw6q 2956 20 seconds second NNS cord-006870-f5w6fw6q 2956 21 ) ) -RRB- cord-006870-f5w6fw6q 2956 22 . . . cord-006870-f5w6fw6q 2957 1 Patients patient NNS cord-006870-f5w6fw6q 2957 2 groups group NNS cord-006870-f5w6fw6q 2957 3 were be VBD cord-006870-f5w6fw6q 2957 4 categorized categorize VBN cord-006870-f5w6fw6q 2957 5 as as IN cord-006870-f5w6fw6q 2957 6 follows follow VBZ cord-006870-f5w6fw6q 2957 7 ; ; : cord-006870-f5w6fw6q 2957 8 1 1 LS cord-006870-f5w6fw6q 2957 9 ) ) -RRB- cord-006870-f5w6fw6q 2957 10 Global global JJ cord-006870-f5w6fw6q 2957 11 cerebral cerebral JJ cord-006870-f5w6fw6q 2957 12 ischemia ischemia NN cord-006870-f5w6fw6q 2957 13 with with IN cord-006870-f5w6fw6q 2957 14 profound profound JJ cord-006870-f5w6fw6q 2957 15 cerebral cerebral JJ cord-006870-f5w6fw6q 2957 16 injury injury NN cord-006870-f5w6fw6q 2957 17 ( ( -LRB- cord-006870-f5w6fw6q 2957 18 N=40 N=40 NNP cord-006870-f5w6fw6q 2957 19 ) ) -RRB- cord-006870-f5w6fw6q 2957 20 , , , cord-006870-f5w6fw6q 2957 21 2 2 CD cord-006870-f5w6fw6q 2957 22 ) ) -RRB- cord-006870-f5w6fw6q 2958 1 Large large JJ cord-006870-f5w6fw6q 2958 2 ischemic ischemic JJ cord-006870-f5w6fw6q 2958 3 stroke stroke NN cord-006870-f5w6fw6q 2958 4 or or CC cord-006870-f5w6fw6q 2958 5 Decrease decrease VB cord-006870-f5w6fw6q 2958 6 in in IN cord-006870-f5w6fw6q 2958 7 CBF CBF NNP cord-006870-f5w6fw6q 2958 8 in in IN cord-006870-f5w6fw6q 2958 9 the the DT cord-006870-f5w6fw6q 2958 10 frontal frontal JJ cord-006870-f5w6fw6q 2958 11 lobe lobe NN cord-006870-f5w6fw6q 2958 12 due due IN cord-006870-f5w6fw6q 2958 13 to to IN cord-006870-f5w6fw6q 2958 14 severe severe JJ cord-006870-f5w6fw6q 2958 15 stenosis stenosis NN cord-006870-f5w6fw6q 2958 16 in in IN cord-006870-f5w6fw6q 2958 17 the the DT cord-006870-f5w6fw6q 2958 18 middle middle JJ cord-006870-f5w6fw6q 2958 19 cerebral cerebral JJ cord-006870-f5w6fw6q 2958 20 artery artery NN cord-006870-f5w6fw6q 2958 21 ( ( -LRB- cord-006870-f5w6fw6q 2958 22 MCA MCA NNP cord-006870-f5w6fw6q 2958 23 ) ) -RRB- cord-006870-f5w6fw6q 2958 24 or or CC cord-006870-f5w6fw6q 2958 25 internal internal JJ cord-006870-f5w6fw6q 2958 26 carotid carotid JJ cord-006870-f5w6fw6q 2958 27 artery artery NN cord-006870-f5w6fw6q 2958 28 ( ( -LRB- cord-006870-f5w6fw6q 2958 29 ICA ICA NNP cord-006870-f5w6fw6q 2958 30 ) ) -RRB- cord-006870-f5w6fw6q 2958 31 ( ( -LRB- cord-006870-f5w6fw6q 2958 32 N=74 N=74 NNP cord-006870-f5w6fw6q 2958 33 ) ) -RRB- cord-006870-f5w6fw6q 2958 34 , , . cord-006870-f5w6fw6q 2959 1 3 3 LS cord-006870-f5w6fw6q 2959 2 ) ) -RRB- cord-006870-f5w6fw6q 2959 3 High high JJ cord-006870-f5w6fw6q 2959 4 grade grade NN cord-006870-f5w6fw6q 2959 5 Subarachnoid Subarachnoid NNP cord-006870-f5w6fw6q 2959 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 2959 7 with with IN cord-006870-f5w6fw6q 2959 8 a a DT cord-006870-f5w6fw6q 2959 9 risk risk NN cord-006870-f5w6fw6q 2959 10 of of IN cord-006870-f5w6fw6q 2959 11 vasospasm vasospasm NN cord-006870-f5w6fw6q 2959 12 ( ( -LRB- cord-006870-f5w6fw6q 2959 13 N=14 N=14 NNP cord-006870-f5w6fw6q 2959 14 ) ) -RRB- cord-006870-f5w6fw6q 2960 1 , , , cord-006870-f5w6fw6q 2960 2 Control Control NNP cord-006870-f5w6fw6q 2960 3 groups group NNS cord-006870-f5w6fw6q 2960 4 did do VBD cord-006870-f5w6fw6q 2960 5 not not RB cord-006870-f5w6fw6q 2960 6 have have VB cord-006870-f5w6fw6q 2960 7 either either DT cord-006870-f5w6fw6q 2960 8 cerebral cerebral JJ cord-006870-f5w6fw6q 2960 9 lesion lesion NN cord-006870-f5w6fw6q 2960 10 or or CC cord-006870-f5w6fw6q 2960 11 CBF CBF NNP cord-006870-f5w6fw6q 2960 12 abnormality abnormality NN cord-006870-f5w6fw6q 2960 13 ( ( -LRB- cord-006870-f5w6fw6q 2960 14 N=22 N=22 NNP cord-006870-f5w6fw6q 2960 15 ) ) -RRB- cord-006870-f5w6fw6q 2960 16 . . . cord-006870-f5w6fw6q 2961 1 Global global JJ cord-006870-f5w6fw6q 2961 2 ischemia ischemia NN cord-006870-f5w6fw6q 2961 3 with with IN cord-006870-f5w6fw6q 2961 4 good good JJ cord-006870-f5w6fw6q 2961 5 functional functional JJ cord-006870-f5w6fw6q 2961 6 outcome outcome NN cord-006870-f5w6fw6q 2961 7 group group NN cord-006870-f5w6fw6q 2961 8 had have VBD cord-006870-f5w6fw6q 2961 9 better well JJR cord-006870-f5w6fw6q 2961 10 OxyHb oxyhb JJ cord-006870-f5w6fw6q 2961 11 level level NN cord-006870-f5w6fw6q 2961 12 ( ( -LRB- cord-006870-f5w6fw6q 2961 13 rSO2 rSO2 NNP cord-006870-f5w6fw6q 2961 14 ) ) -RRB- cord-006870-f5w6fw6q 2961 15 compared compare VBN cord-006870-f5w6fw6q 2961 16 to to IN cord-006870-f5w6fw6q 2961 17 those those DT cord-006870-f5w6fw6q 2961 18 with with IN cord-006870-f5w6fw6q 2961 19 poor poor JJ cord-006870-f5w6fw6q 2961 20 outcome outcome NN cord-006870-f5w6fw6q 2961 21 ( ( -LRB- cord-006870-f5w6fw6q 2961 22 67.4 67.4 CD cord-006870-f5w6fw6q 2961 23 % % NN cord-006870-f5w6fw6q 2961 24 vs. vs. CC cord-006870-f5w6fw6q 2961 25 59.5 59.5 CD cord-006870-f5w6fw6q 2961 26 % % NN cord-006870-f5w6fw6q 2961 27 , , , cord-006870-f5w6fw6q 2961 28 respectively respectively RB cord-006870-f5w6fw6q 2961 29 , , , cord-006870-f5w6fw6q 2961 30 P p NN cord-006870-f5w6fw6q 2961 31 = = SYM cord-006870-f5w6fw6q 2961 32 0.003 0.003 CD cord-006870-f5w6fw6q 2961 33 ) ) -RRB- cord-006870-f5w6fw6q 2961 34 . . . cord-006870-f5w6fw6q 2962 1 Patients patient NNS cord-006870-f5w6fw6q 2962 2 with with IN cord-006870-f5w6fw6q 2962 3 poor poor JJ cord-006870-f5w6fw6q 2962 4 perfusion perfusion NN cord-006870-f5w6fw6q 2962 5 in in IN cord-006870-f5w6fw6q 2962 6 the the DT cord-006870-f5w6fw6q 2962 7 MCA MCA NNP cord-006870-f5w6fw6q 2962 8 territory territory NN cord-006870-f5w6fw6q 2962 9 had have VBD cord-006870-f5w6fw6q 2962 10 low low JJ cord-006870-f5w6fw6q 2962 11 OxyHb oxyhb JJ cord-006870-f5w6fw6q 2962 12 level level NN cord-006870-f5w6fw6q 2962 13 compared compare VBN cord-006870-f5w6fw6q 2962 14 to to TO cord-006870-f5w6fw6q 2962 15 mirror mirror VB cord-006870-f5w6fw6q 2962 16 lead lead VB cord-006870-f5w6fw6q 2962 17 in in IN cord-006870-f5w6fw6q 2962 18 the the DT cord-006870-f5w6fw6q 2962 19 contralateral contralateral JJ cord-006870-f5w6fw6q 2962 20 hemisphere hemisphere NN cord-006870-f5w6fw6q 2962 21 . . . cord-006870-f5w6fw6q 2963 1 OxyHb oxyhb JJ cord-006870-f5w6fw6q 2963 2 level level NN cord-006870-f5w6fw6q 2963 3 in in IN cord-006870-f5w6fw6q 2963 4 patients patient NNS cord-006870-f5w6fw6q 2963 5 with with IN cord-006870-f5w6fw6q 2963 6 decreased decrease VBN cord-006870-f5w6fw6q 2963 7 vasomotor vasomotor NN cord-006870-f5w6fw6q 2963 8 reactivity reactivity NN cord-006870-f5w6fw6q 2963 9 on on IN cord-006870-f5w6fw6q 2963 10 Diamox Diamox NNP cord-006870-f5w6fw6q 2963 11 SPECT SPECT NNP cord-006870-f5w6fw6q 2963 12 had have VBD cord-006870-f5w6fw6q 2963 13 improved improve VBN cord-006870-f5w6fw6q 2963 14 after after IN cord-006870-f5w6fw6q 2963 15 carotid carotid NN cord-006870-f5w6fw6q 2963 16 stenting stenting NN cord-006870-f5w6fw6q 2963 17 . . . cord-006870-f5w6fw6q 2964 1 Three three CD cord-006870-f5w6fw6q 2964 2 patients patient NNS cord-006870-f5w6fw6q 2964 3 who who WP cord-006870-f5w6fw6q 2964 4 underwent undergo VBD cord-006870-f5w6fw6q 2964 5 superficial superficial JJ cord-006870-f5w6fw6q 2964 6 temporal temporal JJ cord-006870-f5w6fw6q 2964 7 artery artery JJ cord-006870-f5w6fw6q 2964 8 - - HYPH cord-006870-f5w6fw6q 2964 9 middle middle JJ cord-006870-f5w6fw6q 2964 10 cerebral cerebral JJ cord-006870-f5w6fw6q 2964 11 artery artery NN cord-006870-f5w6fw6q 2964 12 bypass bypass NN cord-006870-f5w6fw6q 2964 13 surgery surgery NN cord-006870-f5w6fw6q 2964 14 had have VBD cord-006870-f5w6fw6q 2964 15 transient transient JJ cord-006870-f5w6fw6q 2964 16 hyperperfusion hyperperfusion NN cord-006870-f5w6fw6q 2964 17 syndrome syndrome NN cord-006870-f5w6fw6q 2964 18 . . . cord-006870-f5w6fw6q 2965 1 OxyHb OxyHb NNP cord-006870-f5w6fw6q 2965 2 and and CC cord-006870-f5w6fw6q 2965 3 total total JJ cord-006870-f5w6fw6q 2965 4 Hb Hb NNP cord-006870-f5w6fw6q 2965 5 were be VBD cord-006870-f5w6fw6q 2965 6 elevated elevate VBN cord-006870-f5w6fw6q 2965 7 in in IN cord-006870-f5w6fw6q 2965 8 the the DT cord-006870-f5w6fw6q 2965 9 affected affected JJ cord-006870-f5w6fw6q 2965 10 area area NN cord-006870-f5w6fw6q 2965 11 . . . cord-006870-f5w6fw6q 2966 1 Patients patient NNS cord-006870-f5w6fw6q 2966 2 with with IN cord-006870-f5w6fw6q 2966 3 SAH SAH NNP cord-006870-f5w6fw6q 2966 4 and and CC cord-006870-f5w6fw6q 2966 5 vasospasm vasospasm NN cord-006870-f5w6fw6q 2966 6 had have VBD cord-006870-f5w6fw6q 2966 7 blunted blunt VBN cord-006870-f5w6fw6q 2966 8 oscillation oscillation NN cord-006870-f5w6fw6q 2966 9 pattern pattern NN cord-006870-f5w6fw6q 2966 10 of of IN cord-006870-f5w6fw6q 2966 11 OxyHb oxyhb RB cord-006870-f5w6fw6q 2966 12 compared compare VBN cord-006870-f5w6fw6q 2966 13 to to IN cord-006870-f5w6fw6q 2966 14 those those DT cord-006870-f5w6fw6q 2966 15 without without IN cord-006870-f5w6fw6q 2966 16 vasospasm vasospasm NN cord-006870-f5w6fw6q 2966 17 . . . cord-006870-f5w6fw6q 2967 1 Bedside bedside NN cord-006870-f5w6fw6q 2967 2 multichannel multichannel JJ cord-006870-f5w6fw6q 2967 3 measurement measurement NN cord-006870-f5w6fw6q 2967 4 of of IN cord-006870-f5w6fw6q 2967 5 OxyHb OxyHb NNP cord-006870-f5w6fw6q 2967 6 and and CC cord-006870-f5w6fw6q 2967 7 DeoxyHb DeoxyHb NNP cord-006870-f5w6fw6q 2967 8 using use VBG cord-006870-f5w6fw6q 2967 9 fNIRS fnirs NN cord-006870-f5w6fw6q 2967 10 might may MD cord-006870-f5w6fw6q 2967 11 be be VB cord-006870-f5w6fw6q 2967 12 useful useful JJ cord-006870-f5w6fw6q 2967 13 in in IN cord-006870-f5w6fw6q 2967 14 understanding understand VBG cord-006870-f5w6fw6q 2967 15 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 2967 16 changes change NNS cord-006870-f5w6fw6q 2967 17 occurring occur VBG cord-006870-f5w6fw6q 2967 18 in in IN cord-006870-f5w6fw6q 2967 19 patients patient NNS cord-006870-f5w6fw6q 2967 20 with with IN cord-006870-f5w6fw6q 2967 21 acute acute JJ cord-006870-f5w6fw6q 2967 22 brain brain NN cord-006870-f5w6fw6q 2967 23 damage damage NN cord-006870-f5w6fw6q 2967 24 at at IN cord-006870-f5w6fw6q 2967 25 the the DT cord-006870-f5w6fw6q 2967 26 real real JJ cord-006870-f5w6fw6q 2967 27 time time NN cord-006870-f5w6fw6q 2967 28 . . . cord-006870-f5w6fw6q 2968 1 Multimodality multimodality NN cord-006870-f5w6fw6q 2968 2 monitoring monitoring NN cord-006870-f5w6fw6q 2968 3 ( ( -LRB- cord-006870-f5w6fw6q 2968 4 MMM mmm UH cord-006870-f5w6fw6q 2968 5 ) ) -RRB- cord-006870-f5w6fw6q 2968 6 , , , cord-006870-f5w6fw6q 2968 7 brain brain NN cord-006870-f5w6fw6q 2968 8 tissue tissue NN cord-006870-f5w6fw6q 2968 9 oxygenation oxygenation NN cord-006870-f5w6fw6q 2968 10 ( ( -LRB- cord-006870-f5w6fw6q 2968 11 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2968 12 ) ) -RRB- cord-006870-f5w6fw6q 2968 13 and and CC cord-006870-f5w6fw6q 2969 1 Microdialysis Microdialysis NNP cord-006870-f5w6fw6q 2969 2 ( ( -LRB- cord-006870-f5w6fw6q 2969 3 MD MD NNP cord-006870-f5w6fw6q 2969 4 ) ) -RRB- cord-006870-f5w6fw6q 2969 5 in in IN cord-006870-f5w6fw6q 2969 6 SAH SAH NNP cord-006870-f5w6fw6q 2969 7 may may MD cord-006870-f5w6fw6q 2969 8 be be VB cord-006870-f5w6fw6q 2969 9 important important JJ cord-006870-f5w6fw6q 2969 10 to to IN cord-006870-f5w6fw6q 2969 11 the the DT cord-006870-f5w6fw6q 2969 12 treatment treatment NN cord-006870-f5w6fw6q 2969 13 of of IN cord-006870-f5w6fw6q 2969 14 delayed delay VBN cord-006870-f5w6fw6q 2969 15 cerebral cerebral JJ cord-006870-f5w6fw6q 2969 16 ischemia ischemia NN cord-006870-f5w6fw6q 2969 17 ( ( -LRB- cord-006870-f5w6fw6q 2969 18 DCI DCI NNP cord-006870-f5w6fw6q 2969 19 ) ) -RRB- cord-006870-f5w6fw6q 2969 20 . . . cord-006870-f5w6fw6q 2970 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 2970 2 hypothesis hypothesis NN cord-006870-f5w6fw6q 2970 3 was be VBD cord-006870-f5w6fw6q 2970 4 that that DT cord-006870-f5w6fw6q 2970 5 concordance concordance NN cord-006870-f5w6fw6q 2970 6 between between IN cord-006870-f5w6fw6q 2970 7 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2970 8 and and CC cord-006870-f5w6fw6q 2970 9 MD MD NNP cord-006870-f5w6fw6q 2970 10 occurs occur VBZ cord-006870-f5w6fw6q 2970 11 in in IN cord-006870-f5w6fw6q 2970 12 the the DT cord-006870-f5w6fw6q 2970 13 tissue tissue NN cord-006870-f5w6fw6q 2970 14 bed bed NN cord-006870-f5w6fw6q 2970 15 displaying display VBG cord-006870-f5w6fw6q 2970 16 angiographic angiographic JJ cord-006870-f5w6fw6q 2970 17 vasospasm vasospasm NN cord-006870-f5w6fw6q 2970 18 . . . cord-006870-f5w6fw6q 2971 1 This this DT cord-006870-f5w6fw6q 2971 2 retrospective retrospective JJ cord-006870-f5w6fw6q 2971 3 observational observational JJ cord-006870-f5w6fw6q 2971 4 study study NN cord-006870-f5w6fw6q 2971 5 includes include VBZ cord-006870-f5w6fw6q 2971 6 10 10 CD cord-006870-f5w6fw6q 2971 7 patients patient NNS cord-006870-f5w6fw6q 2971 8 with with IN cord-006870-f5w6fw6q 2971 9 SAH SAH NNP cord-006870-f5w6fw6q 2971 10 . . . cord-006870-f5w6fw6q 2972 1 The the DT cord-006870-f5w6fw6q 2972 2 extent extent NN cord-006870-f5w6fw6q 2972 3 of of IN cord-006870-f5w6fw6q 2972 4 angiographic angiographic JJ cord-006870-f5w6fw6q 2972 5 vasospasm vasospasm NN cord-006870-f5w6fw6q 2972 6 for for IN cord-006870-f5w6fw6q 2972 7 each each DT cord-006870-f5w6fw6q 2972 8 vessel vessel NN cord-006870-f5w6fw6q 2972 9 was be VBD cord-006870-f5w6fw6q 2972 10 graded grade VBN cord-006870-f5w6fw6q 2972 11 on on IN cord-006870-f5w6fw6q 2972 12 angiography angiography NN cord-006870-f5w6fw6q 2972 13 by by IN cord-006870-f5w6fw6q 2972 14 the the DT cord-006870-f5w6fw6q 2972 15 on on IN cord-006870-f5w6fw6q 2972 16 call call NNP cord-006870-f5w6fw6q 2972 17 neuro neuro NNP cord-006870-f5w6fw6q 2972 18 - - HYPH cord-006870-f5w6fw6q 2972 19 interventionalist interventionalist NNP cord-006870-f5w6fw6q 2972 20 and and CC cord-006870-f5w6fw6q 2972 21 quantified quantify VBN cord-006870-f5w6fw6q 2972 22 as as IN cord-006870-f5w6fw6q 2972 23 0 0 NFP cord-006870-f5w6fw6q 2972 24 ( ( -LRB- cord-006870-f5w6fw6q 2972 25 no no DT cord-006870-f5w6fw6q 2972 26 spasm spasm NN cord-006870-f5w6fw6q 2972 27 ) ) -RRB- cord-006870-f5w6fw6q 2972 28 to to IN cord-006870-f5w6fw6q 2972 29 6 6 CD cord-006870-f5w6fw6q 2972 30 ( ( -LRB- cord-006870-f5w6fw6q 2972 31 severe severe JJ cord-006870-f5w6fw6q 2972 32 spasm spasm NN cord-006870-f5w6fw6q 2972 33 ) ) -RRB- cord-006870-f5w6fw6q 2972 34 . . . cord-006870-f5w6fw6q 2973 1 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2973 2 and and CC cord-006870-f5w6fw6q 2973 3 MD MD NNP cord-006870-f5w6fw6q 2973 4 probes probe NNS cord-006870-f5w6fw6q 2973 5 were be VBD cord-006870-f5w6fw6q 2973 6 placed place VBN cord-006870-f5w6fw6q 2973 7 in in IN cord-006870-f5w6fw6q 2973 8 the the DT cord-006870-f5w6fw6q 2973 9 frontal frontal JJ cord-006870-f5w6fw6q 2973 10 lobe lobe NNP cord-006870-f5w6fw6q 2973 11 white white JJ cord-006870-f5w6fw6q 2973 12 matter matter NN cord-006870-f5w6fw6q 2973 13 . . . cord-006870-f5w6fw6q 2974 1 The the DT cord-006870-f5w6fw6q 2974 2 severity severity NN cord-006870-f5w6fw6q 2974 3 of of IN cord-006870-f5w6fw6q 2974 4 vasospasm vasospasm NN cord-006870-f5w6fw6q 2974 5 was be VBD cord-006870-f5w6fw6q 2974 6 estimated estimate VBN cord-006870-f5w6fw6q 2974 7 by by IN cord-006870-f5w6fw6q 2974 8 the the DT cord-006870-f5w6fw6q 2974 9 weighted weighted JJ cord-006870-f5w6fw6q 2974 10 average average NN cord-006870-f5w6fw6q 2974 11 of of IN cord-006870-f5w6fw6q 2974 12 ( ( -LRB- cord-006870-f5w6fw6q 2974 13 1x 1x JJ cord-006870-f5w6fw6q 2974 14 ACA ACA NNP cord-006870-f5w6fw6q 2974 15 + + SYM cord-006870-f5w6fw6q 2974 16 2 2 CD cord-006870-f5w6fw6q 2974 17 x x SYM cord-006870-f5w6fw6q 2974 18 MCA MCA NNP cord-006870-f5w6fw6q 2974 19 + + CC cord-006870-f5w6fw6q 2974 20 3 3 CD cord-006870-f5w6fw6q 2974 21 x x SYM cord-006870-f5w6fw6q 2974 22 ICA ICA NNP cord-006870-f5w6fw6q 2974 23 ) ) -RRB- cord-006870-f5w6fw6q 2974 24 / / SYM cord-006870-f5w6fw6q 2974 25 6 6 CD cord-006870-f5w6fw6q 2974 26 . . . cord-006870-f5w6fw6q 2975 1 Cases case NNS cord-006870-f5w6fw6q 2975 2 with with IN cord-006870-f5w6fw6q 2975 3 score score NN cord-006870-f5w6fw6q 2975 4 of of IN cord-006870-f5w6fw6q 2975 5 2 2 CD cord-006870-f5w6fw6q 2975 6 or or CC cord-006870-f5w6fw6q 2975 7 more more JJR cord-006870-f5w6fw6q 2975 8 were be VBD cord-006870-f5w6fw6q 2975 9 considered consider VBN cord-006870-f5w6fw6q 2975 10 to to TO cord-006870-f5w6fw6q 2975 11 have have VB cord-006870-f5w6fw6q 2975 12 clinically clinically RB cord-006870-f5w6fw6q 2975 13 relevant relevant JJ cord-006870-f5w6fw6q 2975 14 vasospasm vasospasm NN cord-006870-f5w6fw6q 2975 15 . . . cord-006870-f5w6fw6q 2976 1 Using use VBG cord-006870-f5w6fw6q 2976 2 a a DT cord-006870-f5w6fw6q 2976 3 within within IN cord-006870-f5w6fw6q 2976 4 - - HYPH cord-006870-f5w6fw6q 2976 5 subjects subject NNS cord-006870-f5w6fw6q 2976 6 design design NN cord-006870-f5w6fw6q 2976 7 , , , cord-006870-f5w6fw6q 2976 8 epochs epoch NNS cord-006870-f5w6fw6q 2976 9 of of IN cord-006870-f5w6fw6q 2976 10 baseline baseline JJ cord-006870-f5w6fw6q 2976 11 MMM MMM NNP cord-006870-f5w6fw6q 2976 12 were be VBD cord-006870-f5w6fw6q 2976 13 compared compare VBN cord-006870-f5w6fw6q 2976 14 with with IN cord-006870-f5w6fw6q 2976 15 during during IN cord-006870-f5w6fw6q 2976 16 spasm spasm NN cord-006870-f5w6fw6q 2976 17 using use VBG cord-006870-f5w6fw6q 2976 18 daily daily RB cord-006870-f5w6fw6q 2976 19 mean mean NN cord-006870-f5w6fw6q 2976 20 for for IN cord-006870-f5w6fw6q 2976 21 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2976 22 , , , cord-006870-f5w6fw6q 2976 23 LPR LPR NNP cord-006870-f5w6fw6q 2976 24 , , , cord-006870-f5w6fw6q 2976 25 glucose glucose NN cord-006870-f5w6fw6q 2976 26 , , , cord-006870-f5w6fw6q 2976 27 ICP ICP NNP cord-006870-f5w6fw6q 2976 28 and and CC cord-006870-f5w6fw6q 2976 29 CPP CPP NNP cord-006870-f5w6fw6q 2976 30 . . . cord-006870-f5w6fw6q 2977 1 Given give VBN cord-006870-f5w6fw6q 2977 2 the the DT cord-006870-f5w6fw6q 2977 3 limited limited JJ cord-006870-f5w6fw6q 2977 4 number number NN cord-006870-f5w6fw6q 2977 5 of of IN cord-006870-f5w6fw6q 2977 6 observations observation NNS cord-006870-f5w6fw6q 2977 7 the the DT cord-006870-f5w6fw6q 2977 8 simplifying simplify VBG cord-006870-f5w6fw6q 2977 9 assumption assumption NN cord-006870-f5w6fw6q 2977 10 was be VBD cord-006870-f5w6fw6q 2977 11 made make VBN cord-006870-f5w6fw6q 2977 12 that that IN cord-006870-f5w6fw6q 2977 13 the the DT cord-006870-f5w6fw6q 2977 14 observations observation NNS cord-006870-f5w6fw6q 2977 15 from from IN cord-006870-f5w6fw6q 2977 16 all all DT cord-006870-f5w6fw6q 2977 17 epochs epoch NNS cord-006870-f5w6fw6q 2977 18 are be VBP cord-006870-f5w6fw6q 2977 19 independent independent JJ cord-006870-f5w6fw6q 2977 20 . . . cord-006870-f5w6fw6q 2978 1 The the DT cord-006870-f5w6fw6q 2978 2 measurements measurement NNS cord-006870-f5w6fw6q 2978 3 from from IN cord-006870-f5w6fw6q 2978 4 all all DT cord-006870-f5w6fw6q 2978 5 patients patient NNS cord-006870-f5w6fw6q 2978 6 were be VBD cord-006870-f5w6fw6q 2978 7 divided divide VBN cord-006870-f5w6fw6q 2978 8 in in IN cord-006870-f5w6fw6q 2978 9 the the DT cord-006870-f5w6fw6q 2978 10 two two CD cord-006870-f5w6fw6q 2978 11 groups group NNS cord-006870-f5w6fw6q 2978 12 with with IN cord-006870-f5w6fw6q 2978 13 and and CC cord-006870-f5w6fw6q 2978 14 without without IN cord-006870-f5w6fw6q 2978 15 spasm spasm NN cord-006870-f5w6fw6q 2978 16 and and CC cord-006870-f5w6fw6q 2978 17 were be VBD cord-006870-f5w6fw6q 2978 18 compared compare VBN cord-006870-f5w6fw6q 2978 19 using use VBG cord-006870-f5w6fw6q 2978 20 a a DT cord-006870-f5w6fw6q 2978 21 twotailed twotailed JJ cord-006870-f5w6fw6q 2978 22 non non JJ cord-006870-f5w6fw6q 2978 23 - - JJ cord-006870-f5w6fw6q 2978 24 paired paired JJ cord-006870-f5w6fw6q 2978 25 student student NN cord-006870-f5w6fw6q 2978 26 T t NN cord-006870-f5w6fw6q 2978 27 - - HYPH cord-006870-f5w6fw6q 2978 28 test test NN cord-006870-f5w6fw6q 2978 29 . . . cord-006870-f5w6fw6q 2979 1 Sixteen sixteen CD cord-006870-f5w6fw6q 2979 2 sets set NNS cord-006870-f5w6fw6q 2979 3 of of IN cord-006870-f5w6fw6q 2979 4 baseline baseline NN cord-006870-f5w6fw6q 2979 5 and and CC cord-006870-f5w6fw6q 2979 6 vasospasm vasospasm NN cord-006870-f5w6fw6q 2979 7 epochs epoch NNS cord-006870-f5w6fw6q 2979 8 were be VBD cord-006870-f5w6fw6q 2979 9 evaluated evaluate VBN cord-006870-f5w6fw6q 2979 10 for for IN cord-006870-f5w6fw6q 2979 11 PBTO2 PBTO2 NNS cord-006870-f5w6fw6q 2979 12 and and CC cord-006870-f5w6fw6q 2979 13 18 18 CD cord-006870-f5w6fw6q 2979 14 for for IN cord-006870-f5w6fw6q 2979 15 MD MD NNP cord-006870-f5w6fw6q 2979 16 . . . cord-006870-f5w6fw6q 2980 1 Compared compare VBN cord-006870-f5w6fw6q 2980 2 with with IN cord-006870-f5w6fw6q 2980 3 baseline baseline JJ cord-006870-f5w6fw6q 2980 4 values value NNS cord-006870-f5w6fw6q 2980 5 , , , cord-006870-f5w6fw6q 2980 6 the the DT cord-006870-f5w6fw6q 2980 7 average average JJ cord-006870-f5w6fw6q 2980 8 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2980 9 was be VBD cord-006870-f5w6fw6q 2980 10 significantly significantly RB cord-006870-f5w6fw6q 2980 11 lower low JJR cord-006870-f5w6fw6q 2980 12 ( ( -LRB- cord-006870-f5w6fw6q 2980 13 15.1 15.1 CD cord-006870-f5w6fw6q 2980 14 vs vs IN cord-006870-f5w6fw6q 2980 15 24.6mmHg 24.6mmhg CD cord-006870-f5w6fw6q 2980 16 , , , cord-006870-f5w6fw6q 2980 17 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 2980 18 ) ) -RRB- cord-006870-f5w6fw6q 2980 19 , , , cord-006870-f5w6fw6q 2980 20 LPR LPR NNP cord-006870-f5w6fw6q 2980 21 was be VBD cord-006870-f5w6fw6q 2980 22 non non JJ cord-006870-f5w6fw6q 2980 23 - - JJ cord-006870-f5w6fw6q 2980 24 significantly significantly RB cord-006870-f5w6fw6q 2980 25 higher high JJR cord-006870-f5w6fw6q 2980 26 ( ( -LRB- cord-006870-f5w6fw6q 2980 27 38.3 38.3 CD cord-006870-f5w6fw6q 2980 28 vs vs IN cord-006870-f5w6fw6q 2980 29 28.4 28.4 CD cord-006870-f5w6fw6q 2980 30 , , , cord-006870-f5w6fw6q 2980 31 p=0.07 p=0.07 NNP cord-006870-f5w6fw6q 2980 32 ) ) -RRB- cord-006870-f5w6fw6q 2980 33 , , , cord-006870-f5w6fw6q 2980 34 and and CC cord-006870-f5w6fw6q 2980 35 glucose glucose NN cord-006870-f5w6fw6q 2980 36 was be VBD cord-006870-f5w6fw6q 2980 37 similar similar JJ cord-006870-f5w6fw6q 2980 38 ( ( -LRB- cord-006870-f5w6fw6q 2980 39 0.9 0.9 CD cord-006870-f5w6fw6q 2980 40 vs vs IN cord-006870-f5w6fw6q 2980 41 1.2 1.2 CD cord-006870-f5w6fw6q 2980 42 mmol mmol JJ cord-006870-f5w6fw6q 2980 43 / / SYM cord-006870-f5w6fw6q 2980 44 l l NN cord-006870-f5w6fw6q 2980 45 , , , cord-006870-f5w6fw6q 2980 46 p= p= NNP cord-006870-f5w6fw6q 2980 47 0.5 0.5 CD cord-006870-f5w6fw6q 2980 48 ) ) -RRB- cord-006870-f5w6fw6q 2980 49 during during IN cord-006870-f5w6fw6q 2980 50 vasospasm vasospasm NN cord-006870-f5w6fw6q 2980 51 epochs epoch NNS cord-006870-f5w6fw6q 2980 52 . . . cord-006870-f5w6fw6q 2981 1 There there EX cord-006870-f5w6fw6q 2981 2 was be VBD cord-006870-f5w6fw6q 2981 3 no no DT cord-006870-f5w6fw6q 2981 4 difference difference NN cord-006870-f5w6fw6q 2981 5 in in IN cord-006870-f5w6fw6q 2981 6 ICP ICP NNP cord-006870-f5w6fw6q 2981 7 ( ( -LRB- cord-006870-f5w6fw6q 2981 8 9.7 9.7 CD cord-006870-f5w6fw6q 2981 9 vs vs IN cord-006870-f5w6fw6q 2981 10 9.7mmHg 9.7mmhg CD cord-006870-f5w6fw6q 2981 11 , , , cord-006870-f5w6fw6q 2981 12 p=0.98 p=0.98 NNP cord-006870-f5w6fw6q 2981 13 ) ) -RRB- cord-006870-f5w6fw6q 2981 14 . . . cord-006870-f5w6fw6q 2982 1 These these DT cord-006870-f5w6fw6q 2982 2 differences difference NNS cord-006870-f5w6fw6q 2982 3 were be VBD cord-006870-f5w6fw6q 2982 4 unaffected unaffected JJ cord-006870-f5w6fw6q 2982 5 by by IN cord-006870-f5w6fw6q 2982 6 induced induce VBN cord-006870-f5w6fw6q 2982 7 hypertension hypertension NN cord-006870-f5w6fw6q 2982 8 , , , cord-006870-f5w6fw6q 2982 9 when when WRB cord-006870-f5w6fw6q 2982 10 CPP CPP NNP cord-006870-f5w6fw6q 2982 11 was be VBD cord-006870-f5w6fw6q 2982 12 augmented augment VBN cord-006870-f5w6fw6q 2982 13 for for IN cord-006870-f5w6fw6q 2982 14 treatment treatment NN cord-006870-f5w6fw6q 2982 15 of of IN cord-006870-f5w6fw6q 2982 16 DCI DCI NNP cord-006870-f5w6fw6q 2982 17 ( ( -LRB- cord-006870-f5w6fw6q 2982 18 120.4 120.4 CD cord-006870-f5w6fw6q 2982 19 vs vs IN cord-006870-f5w6fw6q 2982 20 101.3 101.3 CD cord-006870-f5w6fw6q 2982 21 mmHg mmHg NNS cord-006870-f5w6fw6q 2982 22 , , , cord-006870-f5w6fw6q 2982 23 p=0.07 p=0.07 NNP cord-006870-f5w6fw6q 2982 24 ) ) -RRB- cord-006870-f5w6fw6q 2982 25 . . . cord-006870-f5w6fw6q 2983 1 MMM mmm UH cord-006870-f5w6fw6q 2983 2 during during IN cord-006870-f5w6fw6q 2983 3 angiographic angiographic JJ cord-006870-f5w6fw6q 2983 4 vasospasm vasospasm NN cord-006870-f5w6fw6q 2983 5 after after IN cord-006870-f5w6fw6q 2983 6 SAH SAH NNP cord-006870-f5w6fw6q 2983 7 suggests suggest VBZ cord-006870-f5w6fw6q 2983 8 discordant discordant JJ cord-006870-f5w6fw6q 2983 9 changes change NNS cord-006870-f5w6fw6q 2983 10 in in IN cord-006870-f5w6fw6q 2983 11 brain brain NN cord-006870-f5w6fw6q 2983 12 oxygenation oxygenation NN cord-006870-f5w6fw6q 2983 13 and and CC cord-006870-f5w6fw6q 2983 14 metabolism metabolism NN cord-006870-f5w6fw6q 2983 15 . . . cord-006870-f5w6fw6q 2984 1 These these DT cord-006870-f5w6fw6q 2984 2 data datum NNS cord-006870-f5w6fw6q 2984 3 suggests suggest VBZ cord-006870-f5w6fw6q 2984 4 that that IN cord-006870-f5w6fw6q 2984 5 DCI DCI NNP cord-006870-f5w6fw6q 2984 6 may may MD cord-006870-f5w6fw6q 2984 7 be be VB cord-006870-f5w6fw6q 2984 8 related relate VBN cord-006870-f5w6fw6q 2984 9 to to IN cord-006870-f5w6fw6q 2984 10 metabolic metabolic JJ cord-006870-f5w6fw6q 2984 11 factors factor NNS cord-006870-f5w6fw6q 2984 12 other other JJ cord-006870-f5w6fw6q 2984 13 than than IN cord-006870-f5w6fw6q 2984 14 tissue tissue NN cord-006870-f5w6fw6q 2984 15 oxygenation oxygenation NN cord-006870-f5w6fw6q 2984 16 . . . cord-006870-f5w6fw6q 2985 1 Multimodal Multimodal NNP cord-006870-f5w6fw6q 2985 2 monitoring monitor VBG cord-006870-f5w6fw6q 2985 3 including include VBG cord-006870-f5w6fw6q 2985 4 brain brain NN cord-006870-f5w6fw6q 2985 5 tissue tissue NN cord-006870-f5w6fw6q 2985 6 oxygenation oxygenation NN cord-006870-f5w6fw6q 2985 7 ( ( -LRB- cord-006870-f5w6fw6q 2985 8 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2985 9 ) ) -RRB- cord-006870-f5w6fw6q 2985 10 is be VBZ cord-006870-f5w6fw6q 2985 11 increasingly increasingly RB cord-006870-f5w6fw6q 2985 12 used use VBN cord-006870-f5w6fw6q 2985 13 for for IN cord-006870-f5w6fw6q 2985 14 the the DT cord-006870-f5w6fw6q 2985 15 management management NN cord-006870-f5w6fw6q 2985 16 of of IN cord-006870-f5w6fw6q 2985 17 acute acute JJ cord-006870-f5w6fw6q 2985 18 TBI TBI NNP cord-006870-f5w6fw6q 2985 19 patients patient NNS cord-006870-f5w6fw6q 2985 20 . . . cord-006870-f5w6fw6q 2986 1 The the DT cord-006870-f5w6fw6q 2986 2 optimal optimal JJ cord-006870-f5w6fw6q 2986 3 management management NN cord-006870-f5w6fw6q 2986 4 of of IN cord-006870-f5w6fw6q 2986 5 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2986 6 is be VBZ cord-006870-f5w6fw6q 2986 7 not not RB cord-006870-f5w6fw6q 2986 8 fully fully RB cord-006870-f5w6fw6q 2986 9 established establish VBN cord-006870-f5w6fw6q 2986 10 . . . cord-006870-f5w6fw6q 2987 1 Increasing increase VBG cord-006870-f5w6fw6q 2987 2 FiO2 FiO2 NNS cord-006870-f5w6fw6q 2987 3 is be VBZ cord-006870-f5w6fw6q 2987 4 efficacious efficacious JJ cord-006870-f5w6fw6q 2987 5 to to TO cord-006870-f5w6fw6q 2987 6 correct correct VB cord-006870-f5w6fw6q 2987 7 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2987 8 but but CC cord-006870-f5w6fw6q 2987 9 may may MD cord-006870-f5w6fw6q 2987 10 mask mask VB cord-006870-f5w6fw6q 2987 11 other other JJ cord-006870-f5w6fw6q 2987 12 oxygen oxygen NN cord-006870-f5w6fw6q 2987 13 delivery delivery NN cord-006870-f5w6fw6q 2987 14 mechanisms mechanism NNS cord-006870-f5w6fw6q 2987 15 which which WDT cord-006870-f5w6fw6q 2987 16 may may MD cord-006870-f5w6fw6q 2987 17 be be VB cord-006870-f5w6fw6q 2987 18 deficient deficient JJ cord-006870-f5w6fw6q 2987 19 . . . cord-006870-f5w6fw6q 2988 1 The the DT cord-006870-f5w6fw6q 2988 2 objective objective NN cord-006870-f5w6fw6q 2988 3 of of IN cord-006870-f5w6fw6q 2988 4 this this DT cord-006870-f5w6fw6q 2988 5 study study NN cord-006870-f5w6fw6q 2988 6 was be VBD cord-006870-f5w6fw6q 2988 7 to to TO cord-006870-f5w6fw6q 2988 8 explore explore VB cord-006870-f5w6fw6q 2988 9 the the DT cord-006870-f5w6fw6q 2988 10 clinical clinical JJ cord-006870-f5w6fw6q 2988 11 utility utility NN cord-006870-f5w6fw6q 2988 12 of of IN cord-006870-f5w6fw6q 2988 13 a a DT cord-006870-f5w6fw6q 2988 14 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2988 15 / / SYM cord-006870-f5w6fw6q 2988 16 PaO2 pao2 NN cord-006870-f5w6fw6q 2988 17 ratio ratio NN cord-006870-f5w6fw6q 2988 18 to to TO cord-006870-f5w6fw6q 2988 19 detect detect VB cord-006870-f5w6fw6q 2988 20 overtreatment overtreatment NN cord-006870-f5w6fw6q 2988 21 by by IN cord-006870-f5w6fw6q 2988 22 FiO2 FiO2 NNS cord-006870-f5w6fw6q 2988 23 . . . cord-006870-f5w6fw6q 2989 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 2989 2 cohort cohort NN cord-006870-f5w6fw6q 2989 3 stud stud NN cord-006870-f5w6fw6q 2989 4 were be VBD cord-006870-f5w6fw6q 2989 5 collected collect VBN cord-006870-f5w6fw6q 2989 6 simultaneously simultaneously RB cord-006870-f5w6fw6q 2989 7 whenever whenever WRB cord-006870-f5w6fw6q 2989 8 an an DT cord-006870-f5w6fw6q 2989 9 arterial arterial JJ cord-006870-f5w6fw6q 2989 10 blood blood NN cord-006870-f5w6fw6q 2989 11 gas gas NN cord-006870-f5w6fw6q 2989 12 was be VBD cord-006870-f5w6fw6q 2989 13 drawn draw VBN cord-006870-f5w6fw6q 2989 14 ( ( -LRB- cord-006870-f5w6fw6q 2989 15 ICP ICP NNP cord-006870-f5w6fw6q 2989 16 , , , cord-006870-f5w6fw6q 2989 17 CPP CPP NNP cord-006870-f5w6fw6q 2989 18 , , , cord-006870-f5w6fw6q 2989 19 hemoglobin hemoglobin NN cord-006870-f5w6fw6q 2989 20 , , , cord-006870-f5w6fw6q 2989 21 temperature temperature NN cord-006870-f5w6fw6q 2989 22 , , , cord-006870-f5w6fw6q 2989 23 PCO2 PCO2 NNP cord-006870-f5w6fw6q 2989 24 and and CC cord-006870-f5w6fw6q 2989 25 PaO2 PaO2 NNS cord-006870-f5w6fw6q 2989 26 ) ) -RRB- cord-006870-f5w6fw6q 2989 27 . . . cord-006870-f5w6fw6q 2990 1 Causes cause NNS cord-006870-f5w6fw6q 2990 2 of of IN cord-006870-f5w6fw6q 2990 3 cerebral cerebral JJ cord-006870-f5w6fw6q 2990 4 hypoxia hypoxia NN cord-006870-f5w6fw6q 2990 5 ( ( -LRB- cord-006870-f5w6fw6q 2990 6 PbtO2 pbto2 NN cord-006870-f5w6fw6q 2990 7 < < XX cord-006870-f5w6fw6q 2990 8 20mmHg 20mmhg CD cord-006870-f5w6fw6q 2990 9 ) ) -RRB- cord-006870-f5w6fw6q 2990 10 were be VBD cord-006870-f5w6fw6q 2990 11 noted note VBN cord-006870-f5w6fw6q 2990 12 . . . cord-006870-f5w6fw6q 2991 1 PbtO2 PbtO2 NNS cord-006870-f5w6fw6q 2991 2 / / SYM cord-006870-f5w6fw6q 2991 3 PaO2 pao2 NN cord-006870-f5w6fw6q 2991 4 ratio ratio NN cord-006870-f5w6fw6q 2992 1 < < NNP cord-006870-f5w6fw6q 2992 2 0.15 0.15 CD cord-006870-f5w6fw6q 2992 3 was be VBD cord-006870-f5w6fw6q 2992 4 considered consider VBN cord-006870-f5w6fw6q 2992 5 abnormal abnormal JJ cord-006870-f5w6fw6q 2992 6 and and CC cord-006870-f5w6fw6q 2992 7 plotted plot VBN cord-006870-f5w6fw6q 2992 8 over over IN cord-006870-f5w6fw6q 2992 9 time time NN cord-006870-f5w6fw6q 2992 10 for for IN cord-006870-f5w6fw6q 2992 11 each each DT cord-006870-f5w6fw6q 2992 12 patient patient NN cord-006870-f5w6fw6q 2992 13 individually individually RB cord-006870-f5w6fw6q 2992 14 . . . cord-006870-f5w6fw6q 2993 1 1006 1006 CD cord-006870-f5w6fw6q 2993 2 data data NN cord-006870-f5w6fw6q 2993 3 sets set NNS cord-006870-f5w6fw6q 2993 4 were be VBD cord-006870-f5w6fw6q 2993 5 collected collect VBN cord-006870-f5w6fw6q 2993 6 from from IN cord-006870-f5w6fw6q 2993 7 38 38 CD cord-006870-f5w6fw6q 2993 8 patients patient NNS cord-006870-f5w6fw6q 2993 9 ( ( -LRB- cord-006870-f5w6fw6q 2993 10 mean mean VB cord-006870-f5w6fw6q 2993 11 age age NN cord-006870-f5w6fw6q 2993 12 44.5±20.0 44.5±20.0 CD cord-006870-f5w6fw6q 2993 13 , , , cord-006870-f5w6fw6q 2993 14 median median JJ cord-006870-f5w6fw6q 2993 15 GCS GCS NNP cord-006870-f5w6fw6q 2993 16 4 4 CD cord-006870-f5w6fw6q 2993 17 , , , cord-006870-f5w6fw6q 2993 18 mortality mortality NN cord-006870-f5w6fw6q 2993 19 45 45 CD cord-006870-f5w6fw6q 2993 20 % % NN cord-006870-f5w6fw6q 2993 21 ) ) -RRB- cord-006870-f5w6fw6q 2993 22 . . . cord-006870-f5w6fw6q 2994 1 33.0 33.0 CD cord-006870-f5w6fw6q 2994 2 % % NN cord-006870-f5w6fw6q 2994 3 of of IN cord-006870-f5w6fw6q 2994 4 the the DT cord-006870-f5w6fw6q 2994 5 time time NN cord-006870-f5w6fw6q 2994 6 and and CC cord-006870-f5w6fw6q 2994 7 associated associate VBN cord-006870-f5w6fw6q 2994 8 with with IN cord-006870-f5w6fw6q 2994 9 a a DT cord-006870-f5w6fw6q 2994 10 mean mean JJ cord-006870-f5w6fw6q 2994 11 PaO2 pao2 NN cord-006870-f5w6fw6q 2994 12 of of IN cord-006870-f5w6fw6q 2994 13 250 250 CD cord-006870-f5w6fw6q 2994 14 mmHg mmHg NNS cord-006870-f5w6fw6q 2994 15 . . . cord-006870-f5w6fw6q 2994 16 Measures measure NNS cord-006870-f5w6fw6q 2994 17 within within IN cord-006870-f5w6fw6q 2994 18 the the DT cord-006870-f5w6fw6q 2994 19 low low JJ cord-006870-f5w6fw6q 2994 20 PbtO2-low PbtO2-low NNP cord-006870-f5w6fw6q 2994 21 ratio ratio NN cord-006870-f5w6fw6q 2994 22 category category NN cord-006870-f5w6fw6q 2994 23 had have VBD cord-006870-f5w6fw6q 2994 24 significantly significantly RB cord-006870-f5w6fw6q 2994 25 lower low JJR cord-006870-f5w6fw6q 2994 26 CPP CPP NNP cord-006870-f5w6fw6q 2994 27 ( ( -LRB- cord-006870-f5w6fw6q 2994 28 64 64 CD cord-006870-f5w6fw6q 2994 29 vs vs IN cord-006870-f5w6fw6q 2994 30 72 72 CD cord-006870-f5w6fw6q 2994 31 mmHg mmHg NNS cord-006870-f5w6fw6q 2994 32 ) ) -RRB- cord-006870-f5w6fw6q 2994 33 , , , cord-006870-f5w6fw6q 2994 34 higher high JJR cord-006870-f5w6fw6q 2994 35 PaO2 PaO2 NNS cord-006870-f5w6fw6q 2994 36 ( ( -LRB- cord-006870-f5w6fw6q 2995 1 242 242 CD cord-006870-f5w6fw6q 2995 2 vs vs IN cord-006870-f5w6fw6q 2995 3 130 130 CD cord-006870-f5w6fw6q 2995 4 mmHg mmHg NNS cord-006870-f5w6fw6q 2995 5 ) ) -RRB- cord-006870-f5w6fw6q 2995 6 than than IN cord-006870-f5w6fw6q 2995 7 patients patient NNS cord-006870-f5w6fw6q 2995 8 with with IN cord-006870-f5w6fw6q 2995 9 normal normal JJ cord-006870-f5w6fw6q 2995 10 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2995 11 or or CC cord-006870-f5w6fw6q 2995 12 normal normal JJ cord-006870-f5w6fw6q 2995 13 ratio ratio NN cord-006870-f5w6fw6q 2995 14 respectively respectively RB cord-006870-f5w6fw6q 2995 15 . . . cord-006870-f5w6fw6q 2996 1 Various various JJ cord-006870-f5w6fw6q 2996 2 causes cause NNS cord-006870-f5w6fw6q 2996 3 of of IN cord-006870-f5w6fw6q 2996 4 hypoxic hypoxic JJ cord-006870-f5w6fw6q 2996 5 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 2996 6 were be VBD cord-006870-f5w6fw6q 2996 7 reported report VBN cord-006870-f5w6fw6q 2996 8 when when WRB cord-006870-f5w6fw6q 2996 9 the the DT cord-006870-f5w6fw6q 2996 10 ratio ratio NN cord-006870-f5w6fw6q 2996 11 was be VBD cord-006870-f5w6fw6q 2996 12 abnormal abnormal JJ cord-006870-f5w6fw6q 2996 13 : : : cord-006870-f5w6fw6q 2996 14 hypocapnia hypocapnia NNP cord-006870-f5w6fw6q 2996 15 , , , cord-006870-f5w6fw6q 2996 16 low low JJ cord-006870-f5w6fw6q 2996 17 CPP CPP NNP cord-006870-f5w6fw6q 2996 18 , , , cord-006870-f5w6fw6q 2996 19 low low JJ cord-006870-f5w6fw6q 2996 20 cardiac cardiac JJ cord-006870-f5w6fw6q 2996 21 index index NN cord-006870-f5w6fw6q 2996 22 , , , cord-006870-f5w6fw6q 2996 23 long long JJ cord-006870-f5w6fw6q 2996 24 equilibration equilibration NN cord-006870-f5w6fw6q 2996 25 time time NN cord-006870-f5w6fw6q 2996 26 ... ... : cord-006870-f5w6fw6q 2997 1 Four four CD cord-006870-f5w6fw6q 2997 2 patterns pattern NNS cord-006870-f5w6fw6q 2997 3 of of IN cord-006870-f5w6fw6q 2997 4 evolution evolution NN cord-006870-f5w6fw6q 2997 5 of of IN cord-006870-f5w6fw6q 2997 6 the the DT cord-006870-f5w6fw6q 2997 7 ratio ratio NN cord-006870-f5w6fw6q 2997 8 over over IN cord-006870-f5w6fw6q 2997 9 time time NN cord-006870-f5w6fw6q 2997 10 were be VBD cord-006870-f5w6fw6q 2997 11 identified identify VBN cord-006870-f5w6fw6q 2997 12 and and CC cord-006870-f5w6fw6q 2997 13 associated associate VBN cord-006870-f5w6fw6q 2997 14 with with IN cord-006870-f5w6fw6q 2997 15 different different JJ cord-006870-f5w6fw6q 2997 16 mortality mortality NN cord-006870-f5w6fw6q 2997 17 rate rate NN cord-006870-f5w6fw6q 2997 18 : : : cord-006870-f5w6fw6q 2997 19 28.5 28.5 CD cord-006870-f5w6fw6q 2997 20 % % NN cord-006870-f5w6fw6q 2997 21 , , , cord-006870-f5w6fw6q 2997 22 33.3 33.3 CD cord-006870-f5w6fw6q 2997 23 % % NN cord-006870-f5w6fw6q 2997 24 , , , cord-006870-f5w6fw6q 2997 25 46.7 46.7 CD cord-006870-f5w6fw6q 2997 26 % % NN cord-006870-f5w6fw6q 2997 27 and and CC cord-006870-f5w6fw6q 2997 28 60 60 CD cord-006870-f5w6fw6q 2997 29 % % NN cord-006870-f5w6fw6q 2997 30 . . . cord-006870-f5w6fw6q 2998 1 Conclusions conclusion NNS cord-006870-f5w6fw6q 2998 2 associated associate VBN cord-006870-f5w6fw6q 2998 3 with with IN cord-006870-f5w6fw6q 2998 4 increased increase VBN cord-006870-f5w6fw6q 2998 5 PaO2 PaO2 NNS cord-006870-f5w6fw6q 2998 6 and and CC cord-006870-f5w6fw6q 2998 7 decreased decrease VBD cord-006870-f5w6fw6q 2998 8 CPP CPP NNP cord-006870-f5w6fw6q 2998 9 . . . cord-006870-f5w6fw6q 2999 1 This this DT cord-006870-f5w6fw6q 2999 2 suggests suggest VBZ cord-006870-f5w6fw6q 2999 3 clinicians clinician NNS cord-006870-f5w6fw6q 2999 4 often often RB cord-006870-f5w6fw6q 2999 5 used use VBD cord-006870-f5w6fw6q 2999 6 FiO2 FiO2 NNS cord-006870-f5w6fw6q 2999 7 to to TO cord-006870-f5w6fw6q 2999 8 compensate compensate VB cord-006870-f5w6fw6q 2999 9 for for IN cord-006870-f5w6fw6q 2999 10 deficient deficient JJ cord-006870-f5w6fw6q 2999 11 cerebral cerebral JJ cord-006870-f5w6fw6q 2999 12 oxygen oxygen NN cord-006870-f5w6fw6q 2999 13 delivery delivery NN cord-006870-f5w6fw6q 2999 14 . . . cord-006870-f5w6fw6q 3000 1 Indeed indeed RB cord-006870-f5w6fw6q 3000 2 , , , cord-006870-f5w6fw6q 3000 3 various various JJ cord-006870-f5w6fw6q 3000 4 causes cause NNS cord-006870-f5w6fw6q 3000 5 of of IN cord-006870-f5w6fw6q 3000 6 hypoxia hypoxia NN cord-006870-f5w6fw6q 3000 7 besides besides IN cord-006870-f5w6fw6q 3000 8 low low JJ cord-006870-f5w6fw6q 3000 9 PaO2 PaO2 NNS cord-006870-f5w6fw6q 3000 10 were be VBD cord-006870-f5w6fw6q 3000 11 identified identify VBN cord-006870-f5w6fw6q 3000 12 and and CC cord-006870-f5w6fw6q 3000 13 corrected correct VBN cord-006870-f5w6fw6q 3000 14 . . . cord-006870-f5w6fw6q 3001 1 Pattern pattern NN cord-006870-f5w6fw6q 3001 2 of of IN cord-006870-f5w6fw6q 3001 3 temporal temporal JJ cord-006870-f5w6fw6q 3001 4 evolution evolution NN cord-006870-f5w6fw6q 3001 5 of of IN cord-006870-f5w6fw6q 3001 6 the the DT cord-006870-f5w6fw6q 3001 7 ratio ratio NN cord-006870-f5w6fw6q 3001 8 seems seem VBZ cord-006870-f5w6fw6q 3001 9 to to TO cord-006870-f5w6fw6q 3001 10 correlate correlate VB cord-006870-f5w6fw6q 3001 11 with with IN cord-006870-f5w6fw6q 3001 12 mortality mortality NN cord-006870-f5w6fw6q 3001 13 . . . cord-006870-f5w6fw6q 3002 1 Pupillary pupillary JJ cord-006870-f5w6fw6q 3002 2 light light JJ cord-006870-f5w6fw6q 3002 3 response response NN cord-006870-f5w6fw6q 3002 4 ( ( -LRB- cord-006870-f5w6fw6q 3002 5 PLR plr NN cord-006870-f5w6fw6q 3002 6 ) ) -RRB- cord-006870-f5w6fw6q 3002 7 evaluates evaluate VBZ cord-006870-f5w6fw6q 3002 8 cranial cranial JJ cord-006870-f5w6fw6q 3002 9 nerves nerve NNS cord-006870-f5w6fw6q 3002 10 II II NNP cord-006870-f5w6fw6q 3002 11 , , , cord-006870-f5w6fw6q 3002 12 III III NNP cord-006870-f5w6fw6q 3002 13 , , , cord-006870-f5w6fw6q 3002 14 and and CC cord-006870-f5w6fw6q 3002 15 midbrain midbrain NN cord-006870-f5w6fw6q 3002 16 function function NN cord-006870-f5w6fw6q 3002 17 . . . cord-006870-f5w6fw6q 3003 1 Bedside bedside JJ cord-006870-f5w6fw6q 3003 2 quantitative quantitative JJ cord-006870-f5w6fw6q 3003 3 infrared infrared JJ cord-006870-f5w6fw6q 3003 4 pupillometry pupillometry NNP cord-006870-f5w6fw6q 3003 5 provides provide VBZ cord-006870-f5w6fw6q 3003 6 reproducible reproducible JJ cord-006870-f5w6fw6q 3003 7 assessment assessment NN cord-006870-f5w6fw6q 3003 8 of of IN cord-006870-f5w6fw6q 3003 9 the the DT cord-006870-f5w6fw6q 3003 10 PLR plr NN cord-006870-f5w6fw6q 3003 11 , , , cord-006870-f5w6fw6q 3003 12 reported report VBD cord-006870-f5w6fw6q 3003 13 as as IN cord-006870-f5w6fw6q 3003 14 the the DT cord-006870-f5w6fw6q 3003 15 neurological neurological JJ cord-006870-f5w6fw6q 3003 16 pupillary pupillary JJ cord-006870-f5w6fw6q 3003 17 index index NN cord-006870-f5w6fw6q 3003 18 ( ( -LRB- cord-006870-f5w6fw6q 3003 19 NPI NPI NNP cord-006870-f5w6fw6q 3003 20 ) ) -RRB- cord-006870-f5w6fw6q 3003 21 . . . cord-006870-f5w6fw6q 3004 1 Increased increase VBN cord-006870-f5w6fw6q 3004 2 intracranial intracranial JJ cord-006870-f5w6fw6q 3004 3 pressure pressure NN cord-006870-f5w6fw6q 3004 4 results result NNS cord-006870-f5w6fw6q 3004 5 in in IN cord-006870-f5w6fw6q 3004 6 decreases decrease NNS cord-006870-f5w6fw6q 3004 7 in in IN cord-006870-f5w6fw6q 3004 8 NPI NPI NNP cord-006870-f5w6fw6q 3004 9 . . . cord-006870-f5w6fw6q 3005 1 Intracranial intracranial JJ cord-006870-f5w6fw6q 3005 2 hypotension hypotension NN cord-006870-f5w6fw6q 3005 3 ( ( -LRB- cord-006870-f5w6fw6q 3005 4 IH IH NNP cord-006870-f5w6fw6q 3005 5 ) ) -RRB- cord-006870-f5w6fw6q 3005 6 can can MD cord-006870-f5w6fw6q 3005 7 also also RB cord-006870-f5w6fw6q 3005 8 cause cause VB cord-006870-f5w6fw6q 3005 9 brainstem brainstem NN cord-006870-f5w6fw6q 3005 10 distortion distortion NN cord-006870-f5w6fw6q 3005 11 . . . cord-006870-f5w6fw6q 3006 1 We -PRON- PRP cord-006870-f5w6fw6q 3006 2 therefore therefore RB cord-006870-f5w6fw6q 3006 3 hypothesized hypothesize VBD cord-006870-f5w6fw6q 3006 4 that that IN cord-006870-f5w6fw6q 3006 5 similar similar JJ cord-006870-f5w6fw6q 3006 6 changes change NNS cord-006870-f5w6fw6q 3006 7 in in IN cord-006870-f5w6fw6q 3006 8 NPI NPI NNP cord-006870-f5w6fw6q 3006 9 could could MD cord-006870-f5w6fw6q 3006 10 be be VB cord-006870-f5w6fw6q 3006 11 seen see VBN cord-006870-f5w6fw6q 3006 12 with with IN cord-006870-f5w6fw6q 3006 13 IH IH NNP cord-006870-f5w6fw6q 3006 14 . . . cord-006870-f5w6fw6q 3007 1 Here here RB cord-006870-f5w6fw6q 3007 2 , , , cord-006870-f5w6fw6q 3007 3 we -PRON- PRP cord-006870-f5w6fw6q 3007 4 describe describe VBP cord-006870-f5w6fw6q 3007 5 sequential sequential JJ cord-006870-f5w6fw6q 3007 6 changes change NNS cord-006870-f5w6fw6q 3007 7 in in IN cord-006870-f5w6fw6q 3007 8 NPI NPI NNP cord-006870-f5w6fw6q 3007 9 in in IN cord-006870-f5w6fw6q 3007 10 IH IH NNP cord-006870-f5w6fw6q 3007 11 before before IN cord-006870-f5w6fw6q 3007 12 and and CC cord-006870-f5w6fw6q 3007 13 after after IN cord-006870-f5w6fw6q 3007 14 treatment treatment NN cord-006870-f5w6fw6q 3007 15 . . . cord-006870-f5w6fw6q 3008 1 We -PRON- PRP cord-006870-f5w6fw6q 3008 2 identified identify VBD cord-006870-f5w6fw6q 3008 3 four four CD cord-006870-f5w6fw6q 3008 4 patients patient NNS cord-006870-f5w6fw6q 3008 5 monitored monitor VBN cord-006870-f5w6fw6q 3008 6 with with IN cord-006870-f5w6fw6q 3008 7 pupillometry pupillometry NN cord-006870-f5w6fw6q 3008 8 for for IN cord-006870-f5w6fw6q 3008 9 clinical clinical JJ cord-006870-f5w6fw6q 3008 10 care care NN cord-006870-f5w6fw6q 3008 11 during during IN cord-006870-f5w6fw6q 3008 12 IH IH NNP cord-006870-f5w6fw6q 3008 13 diagnosis diagnosis NN cord-006870-f5w6fw6q 3008 14 and and CC cord-006870-f5w6fw6q 3008 15 treatment treatment NN cord-006870-f5w6fw6q 3008 16 . . . cord-006870-f5w6fw6q 3009 1 IH IH NNP cord-006870-f5w6fw6q 3009 2 was be VBD cord-006870-f5w6fw6q 3009 3 diagnosed diagnose VBN cord-006870-f5w6fw6q 3009 4 with with IN cord-006870-f5w6fw6q 3009 5 a a DT cord-006870-f5w6fw6q 3009 6 compatible compatible JJ cord-006870-f5w6fw6q 3009 7 history history NN cord-006870-f5w6fw6q 3009 8 , , , cord-006870-f5w6fw6q 3009 9 exam exam NN cord-006870-f5w6fw6q 3009 10 , , , cord-006870-f5w6fw6q 3009 11 and and CC cord-006870-f5w6fw6q 3009 12 characteristic characteristic JJ cord-006870-f5w6fw6q 3009 13 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 3009 14 findings finding NNS cord-006870-f5w6fw6q 3009 15 . . . cord-006870-f5w6fw6q 3010 1 Patients patient NNS cord-006870-f5w6fw6q 3010 2 ' ' POS cord-006870-f5w6fw6q 3010 3 NPI npi NN cord-006870-f5w6fw6q 3010 4 at at IN cord-006870-f5w6fw6q 3010 5 baseline baseline NN cord-006870-f5w6fw6q 3010 6 , , , cord-006870-f5w6fw6q 3010 7 during during IN cord-006870-f5w6fw6q 3010 8 symptomatic symptomatic JJ cord-006870-f5w6fw6q 3010 9 IH IH NNP cord-006870-f5w6fw6q 3010 10 , , , cord-006870-f5w6fw6q 3010 11 and and CC cord-006870-f5w6fw6q 3010 12 after after IN cord-006870-f5w6fw6q 3010 13 treatment treatment NN cord-006870-f5w6fw6q 3010 14 were be VBD cord-006870-f5w6fw6q 3010 15 compared compare VBN cord-006870-f5w6fw6q 3010 16 using use VBG cord-006870-f5w6fw6q 3010 17 related relate VBN cord-006870-f5w6fw6q 3010 18 samples sample NNS cord-006870-f5w6fw6q 3010 19 Friedman Friedman NNP cord-006870-f5w6fw6q 3010 20 's 's POS cord-006870-f5w6fw6q 3010 21 two two CD cord-006870-f5w6fw6q 3010 22 - - HYPH cord-006870-f5w6fw6q 3010 23 way way NN cord-006870-f5w6fw6q 3010 24 ANOVA ANOVA NNP cord-006870-f5w6fw6q 3010 25 and and CC cord-006870-f5w6fw6q 3010 26 Wilcoxon Wilcoxon NNP cord-006870-f5w6fw6q 3010 27 signed sign VBD cord-006870-f5w6fw6q 3010 28 ranks rank NNS cord-006870-f5w6fw6q 3010 29 tests test NNS cord-006870-f5w6fw6q 3010 30 . . . cord-006870-f5w6fw6q 3011 1 Two two CD cord-006870-f5w6fw6q 3011 2 patients patient NNS cord-006870-f5w6fw6q 3011 3 were be VBD cord-006870-f5w6fw6q 3011 4 male male JJ cord-006870-f5w6fw6q 3011 5 ; ; , cord-006870-f5w6fw6q 3011 6 causes cause NNS cord-006870-f5w6fw6q 3011 7 of of IN cord-006870-f5w6fw6q 3011 8 IH IH NNP cord-006870-f5w6fw6q 3011 9 were be VBD cord-006870-f5w6fw6q 3011 10 CSF CSF NNP cord-006870-f5w6fw6q 3011 11 leak leak NN cord-006870-f5w6fw6q 3011 12 following follow VBG cord-006870-f5w6fw6q 3011 13 lumbar lumbar NN cord-006870-f5w6fw6q 3011 14 instrumentation instrumentation NN cord-006870-f5w6fw6q 3011 15 ( ( -LRB- cord-006870-f5w6fw6q 3011 16 n=3 n=3 NN cord-006870-f5w6fw6q 3011 17 ) ) -RRB- cord-006870-f5w6fw6q 3011 18 and and CC cord-006870-f5w6fw6q 3011 19 basilar basilar JJ cord-006870-f5w6fw6q 3011 20 skull skull NN cord-006870-f5w6fw6q 3011 21 fracture fracture NN cord-006870-f5w6fw6q 3011 22 ( ( -LRB- cord-006870-f5w6fw6q 3011 23 n=1 n=1 FW cord-006870-f5w6fw6q 3011 24 ) ) -RRB- cord-006870-f5w6fw6q 3011 25 . . . cord-006870-f5w6fw6q 3012 1 Mean mean VB cord-006870-f5w6fw6q 3012 2 baseline baseline JJ cord-006870-f5w6fw6q 3012 3 NPI npi NN cord-006870-f5w6fw6q 3012 4 was be VBD cord-006870-f5w6fw6q 3012 5 normal normal JJ cord-006870-f5w6fw6q 3012 6 ( ( -LRB- cord-006870-f5w6fw6q 3012 7 defined define VBN cord-006870-f5w6fw6q 3012 8 as as IN cord-006870-f5w6fw6q 3012 9 > > XX cord-006870-f5w6fw6q 3012 10 3 3 CD cord-006870-f5w6fw6q 3012 11 ) ) -RRB- cord-006870-f5w6fw6q 3012 12 and and CC cord-006870-f5w6fw6q 3012 13 declined decline VBD cord-006870-f5w6fw6q 3012 14 in in IN cord-006870-f5w6fw6q 3012 15 one one CD cord-006870-f5w6fw6q 3012 16 or or CC cord-006870-f5w6fw6q 3012 17 both both DT cord-006870-f5w6fw6q 3012 18 eyes eye NNS cord-006870-f5w6fw6q 3012 19 concurrent concurrent JJ cord-006870-f5w6fw6q 3012 20 with with IN cord-006870-f5w6fw6q 3012 21 clinical clinical JJ cord-006870-f5w6fw6q 3012 22 deterioration deterioration NN cord-006870-f5w6fw6q 3012 23 in in IN cord-006870-f5w6fw6q 3012 24 the the DT cord-006870-f5w6fw6q 3012 25 24 24 CD cord-006870-f5w6fw6q 3012 26 - - SYM cord-006870-f5w6fw6q 3012 27 48 48 CD cord-006870-f5w6fw6q 3012 28 hours hour NNS cord-006870-f5w6fw6q 3012 29 preceding precede VBG cord-006870-f5w6fw6q 3012 30 definitive definitive JJ cord-006870-f5w6fw6q 3012 31 diagnosis diagnosis NN cord-006870-f5w6fw6q 3012 32 . . . cord-006870-f5w6fw6q 3013 1 All all DT cord-006870-f5w6fw6q 3013 2 patients patient NNS cord-006870-f5w6fw6q 3013 3 underwent undergo VBD cord-006870-f5w6fw6q 3013 4 treatment treatment NN cord-006870-f5w6fw6q 3013 5 for for IN cord-006870-f5w6fw6q 3013 6 CSF CSF NNP cord-006870-f5w6fw6q 3013 7 leak leak NN cord-006870-f5w6fw6q 3013 8 with with IN cord-006870-f5w6fw6q 3013 9 epidural epidural NN cord-006870-f5w6fw6q 3013 10 blood blood NN cord-006870-f5w6fw6q 3013 11 patch patch NN cord-006870-f5w6fw6q 3013 12 or or CC cord-006870-f5w6fw6q 3013 13 fracture fracture NN cord-006870-f5w6fw6q 3013 14 repair repair NN cord-006870-f5w6fw6q 3013 15 , , , cord-006870-f5w6fw6q 3013 16 with with IN cord-006870-f5w6fw6q 3013 17 return return NN cord-006870-f5w6fw6q 3013 18 of of IN cord-006870-f5w6fw6q 3013 19 NPI npi NN cord-006870-f5w6fw6q 3013 20 > > XX cord-006870-f5w6fw6q 3014 1 3 3 LS cord-006870-f5w6fw6q 3014 2 within within IN cord-006870-f5w6fw6q 3014 3 5 5 CD cord-006870-f5w6fw6q 3014 4 hours hour NNS cord-006870-f5w6fw6q 3014 5 of of IN cord-006870-f5w6fw6q 3014 6 treatment treatment NN cord-006870-f5w6fw6q 3014 7 . . . cord-006870-f5w6fw6q 3015 1 The the DT cord-006870-f5w6fw6q 3015 2 baseline baseline JJ cord-006870-f5w6fw6q 3015 3 , , , cord-006870-f5w6fw6q 3015 4 symptomatic symptomatic JJ cord-006870-f5w6fw6q 3015 5 and and CC cord-006870-f5w6fw6q 3015 6 post post JJ cord-006870-f5w6fw6q 3015 7 treatment treatment NN cord-006870-f5w6fw6q 3015 8 NPI NPI NNP cord-006870-f5w6fw6q 3015 9 's 's POS cord-006870-f5w6fw6q 3015 10 differed differ VBN cord-006870-f5w6fw6q 3015 11 significantly significantly RB cord-006870-f5w6fw6q 3015 12 ( ( -LRB- cord-006870-f5w6fw6q 3015 13 3.55±0.35 3.55±0.35 CD cord-006870-f5w6fw6q 3015 14 vs vs IN cord-006870-f5w6fw6q 3015 15 0.80±0.59 0.80±0.59 CD cord-006870-f5w6fw6q 3016 1 vs vs IN cord-006870-f5w6fw6q 3016 2 3.65±0.24 3.65±0.24 CD cord-006870-f5w6fw6q 3017 1 , , , cord-006870-f5w6fw6q 3017 2 mean mean VB cord-006870-f5w6fw6q 3017 3 + + CC cord-006870-f5w6fw6q 3017 4 /-SD /-sd NN cord-006870-f5w6fw6q 3017 5 , , , cord-006870-f5w6fw6q 3017 6 pre pre JJ cord-006870-f5w6fw6q 3017 7 - - JJ cord-006870-f5w6fw6q 3017 8 treatment treatment NN cord-006870-f5w6fw6q 3017 9 vs vs IN cord-006870-f5w6fw6q 3017 10 nadir nadir NNP cord-006870-f5w6fw6q 3017 11 vs vs IN cord-006870-f5w6fw6q 3017 12 post post JJ cord-006870-f5w6fw6q 3017 13 - - JJ cord-006870-f5w6fw6q 3017 14 treatment treatment JJ cord-006870-f5w6fw6q 3017 15 , , , cord-006870-f5w6fw6q 3017 16 p=0.05 p=0.05 NNP cord-006870-f5w6fw6q 3017 17 ) ) -RRB- cord-006870-f5w6fw6q 3017 18 . . . cord-006870-f5w6fw6q 3018 1 Both both DT cord-006870-f5w6fw6q 3018 2 baseline baseline NN cord-006870-f5w6fw6q 3018 3 and and CC cord-006870-f5w6fw6q 3018 4 post post NN cord-006870-f5w6fw6q 3018 5 treatment treatment NN cord-006870-f5w6fw6q 3018 6 NPI NPI NNP cord-006870-f5w6fw6q 3018 7 's 's POS cord-006870-f5w6fw6q 3018 8 differed differ VBN cord-006870-f5w6fw6q 3018 9 from from IN cord-006870-f5w6fw6q 3018 10 the the DT cord-006870-f5w6fw6q 3018 11 NPI NPI NNP cord-006870-f5w6fw6q 3018 12 nadir nadir NN cord-006870-f5w6fw6q 3018 13 ( ( -LRB- cord-006870-f5w6fw6q 3018 14 p=0.068 p=0.068 NNS cord-006870-f5w6fw6q 3018 15 ) ) -RRB- cord-006870-f5w6fw6q 3019 1 but but CC cord-006870-f5w6fw6q 3019 2 there there EX cord-006870-f5w6fw6q 3019 3 was be VBD cord-006870-f5w6fw6q 3019 4 no no DT cord-006870-f5w6fw6q 3019 5 difference difference NN cord-006870-f5w6fw6q 3019 6 between between IN cord-006870-f5w6fw6q 3019 7 baseline baseline NN cord-006870-f5w6fw6q 3019 8 and and CC cord-006870-f5w6fw6q 3019 9 post post JJ cord-006870-f5w6fw6q 3019 10 - - JJ cord-006870-f5w6fw6q 3019 11 treatment treatment JJ cord-006870-f5w6fw6q 3019 12 NPI npi NN cord-006870-f5w6fw6q 3019 13 ( ( -LRB- cord-006870-f5w6fw6q 3019 14 p p NN cord-006870-f5w6fw6q 3019 15 = = SYM cord-006870-f5w6fw6q 3019 16 0.71 0.71 CD cord-006870-f5w6fw6q 3019 17 ) ) -RRB- cord-006870-f5w6fw6q 3019 18 . . . cord-006870-f5w6fw6q 3020 1 Impairment impairment NN cord-006870-f5w6fw6q 3020 2 of of IN cord-006870-f5w6fw6q 3020 3 the the DT cord-006870-f5w6fw6q 3020 4 PLR plr NN cord-006870-f5w6fw6q 3020 5 , , , cord-006870-f5w6fw6q 3020 6 as as IN cord-006870-f5w6fw6q 3020 7 measured measure VBN cord-006870-f5w6fw6q 3020 8 by by IN cord-006870-f5w6fw6q 3020 9 NPI NPI NNP cord-006870-f5w6fw6q 3020 10 , , , cord-006870-f5w6fw6q 3020 11 occurred occur VBD cord-006870-f5w6fw6q 3020 12 during during IN cord-006870-f5w6fw6q 3020 13 symptomatic symptomatic JJ cord-006870-f5w6fw6q 3020 14 IH IH NNP cord-006870-f5w6fw6q 3020 15 and and CC cord-006870-f5w6fw6q 3020 16 resolved resolve VBN cord-006870-f5w6fw6q 3020 17 after after IN cord-006870-f5w6fw6q 3020 18 treatment treatment NN cord-006870-f5w6fw6q 3020 19 . . . cord-006870-f5w6fw6q 3021 1 Because because IN cord-006870-f5w6fw6q 3021 2 management management NN cord-006870-f5w6fw6q 3021 3 of of IN cord-006870-f5w6fw6q 3021 4 intracranial intracranial JJ cord-006870-f5w6fw6q 3021 5 hyper hyper JJ cord-006870-f5w6fw6q 3021 6 - - HYPH cord-006870-f5w6fw6q 3021 7 and and CC cord-006870-f5w6fw6q 3021 8 hypotension hypotension NN cord-006870-f5w6fw6q 3021 9 differ differ VBP cord-006870-f5w6fw6q 3021 10 markedly markedly RB cord-006870-f5w6fw6q 3021 11 , , , cord-006870-f5w6fw6q 3021 12 our -PRON- PRP$ cord-006870-f5w6fw6q 3021 13 results result NNS cord-006870-f5w6fw6q 3021 14 emphasize emphasize VBP cord-006870-f5w6fw6q 3021 15 the the DT cord-006870-f5w6fw6q 3021 16 importance importance NN cord-006870-f5w6fw6q 3021 17 of of IN cord-006870-f5w6fw6q 3021 18 evaluating evaluate VBG cord-006870-f5w6fw6q 3021 19 the the DT cord-006870-f5w6fw6q 3021 20 clinical clinical JJ cord-006870-f5w6fw6q 3021 21 context context NN cord-006870-f5w6fw6q 3021 22 before before IN cord-006870-f5w6fw6q 3021 23 attributing attribute VBG cord-006870-f5w6fw6q 3021 24 pupillary pupillary JJ cord-006870-f5w6fw6q 3021 25 / / SYM cord-006870-f5w6fw6q 3021 26 NPI npi NN cord-006870-f5w6fw6q 3021 27 changes change NNS cord-006870-f5w6fw6q 3021 28 to to IN cord-006870-f5w6fw6q 3021 29 increased increase VBN cord-006870-f5w6fw6q 3021 30 ICP ICP NNP cord-006870-f5w6fw6q 3021 31 . . . cord-006870-f5w6fw6q 3022 1 Automated Automated NNP cord-006870-f5w6fw6q 3022 2 pupillometry pupillometry NNP cord-006870-f5w6fw6q 3022 3 provides provide VBZ cord-006870-f5w6fw6q 3022 4 a a DT cord-006870-f5w6fw6q 3022 5 non non JJ cord-006870-f5w6fw6q 3022 6 - - JJ cord-006870-f5w6fw6q 3022 7 invasive invasive JJ cord-006870-f5w6fw6q 3022 8 , , , cord-006870-f5w6fw6q 3022 9 bedside bedside NN cord-006870-f5w6fw6q 3022 10 tool tool NN cord-006870-f5w6fw6q 3022 11 for for IN cord-006870-f5w6fw6q 3022 12 monitoring monitor VBG cord-006870-f5w6fw6q 3022 13 progression progression NN cord-006870-f5w6fw6q 3022 14 and and CC cord-006870-f5w6fw6q 3022 15 treatment treatment NN cord-006870-f5w6fw6q 3022 16 of of IN cord-006870-f5w6fw6q 3022 17 intracranial intracranial JJ cord-006870-f5w6fw6q 3022 18 hypotension hypotension NN cord-006870-f5w6fw6q 3023 1 The the DT cord-006870-f5w6fw6q 3023 2 correlation correlation NN cord-006870-f5w6fw6q 3023 3 of of IN cord-006870-f5w6fw6q 3023 4 optic optic JJ cord-006870-f5w6fw6q 3023 5 nerve nerve NN cord-006870-f5w6fw6q 3023 6 sheath sheath NN cord-006870-f5w6fw6q 3023 7 diameter diameter NN cord-006870-f5w6fw6q 3023 8 ( ( -LRB- cord-006870-f5w6fw6q 3023 9 ONSD ONSD NNP cord-006870-f5w6fw6q 3023 10 ) ) -RRB- cord-006870-f5w6fw6q 3023 11 as as IN cord-006870-f5w6fw6q 3023 12 seen see VBN cord-006870-f5w6fw6q 3023 13 on on IN cord-006870-f5w6fw6q 3023 14 ultrasonography ultrasonography NN cord-006870-f5w6fw6q 3023 15 ( ( -LRB- cord-006870-f5w6fw6q 3023 16 US US NNP cord-006870-f5w6fw6q 3023 17 ) ) -RRB- cord-006870-f5w6fw6q 3023 18 and and CC cord-006870-f5w6fw6q 3023 19 directly directly RB cord-006870-f5w6fw6q 3023 20 measured measure VBN cord-006870-f5w6fw6q 3023 21 intracranial intracranial JJ cord-006870-f5w6fw6q 3023 22 pressure pressure NN cord-006870-f5w6fw6q 3023 23 ( ( -LRB- cord-006870-f5w6fw6q 3023 24 ICP ICP NNP cord-006870-f5w6fw6q 3023 25 ) ) -RRB- cord-006870-f5w6fw6q 3023 26 has have VBZ cord-006870-f5w6fw6q 3023 27 been be VBN cord-006870-f5w6fw6q 3023 28 well well RB cord-006870-f5w6fw6q 3023 29 described describe VBN cord-006870-f5w6fw6q 3023 30 . . . cord-006870-f5w6fw6q 3024 1 Nevertheless nevertheless RB cord-006870-f5w6fw6q 3024 2 , , , cord-006870-f5w6fw6q 3024 3 differences difference NNS cord-006870-f5w6fw6q 3024 4 in in IN cord-006870-f5w6fw6q 3024 5 ethnicity ethnicity NN cord-006870-f5w6fw6q 3024 6 and and CC cord-006870-f5w6fw6q 3024 7 type type NN cord-006870-f5w6fw6q 3024 8 of of IN cord-006870-f5w6fw6q 3024 9 ICP ICP NNP cord-006870-f5w6fw6q 3024 10 monitor monitor NN cord-006870-f5w6fw6q 3024 11 used use VBN cord-006870-f5w6fw6q 3024 12 are be VBP cord-006870-f5w6fw6q 3024 13 obstacles obstacle NNS cord-006870-f5w6fw6q 3024 14 to to IN cord-006870-f5w6fw6q 3024 15 the the DT cord-006870-f5w6fw6q 3024 16 interpretation interpretation NN cord-006870-f5w6fw6q 3024 17 . . . cord-006870-f5w6fw6q 3025 1 Therefore therefore RB cord-006870-f5w6fw6q 3025 2 , , , cord-006870-f5w6fw6q 3025 3 we -PRON- PRP cord-006870-f5w6fw6q 3025 4 investigated investigate VBD cord-006870-f5w6fw6q 3025 5 the the DT cord-006870-f5w6fw6q 3025 6 direct direct JJ cord-006870-f5w6fw6q 3025 7 correlation correlation NN cord-006870-f5w6fw6q 3025 8 between between IN cord-006870-f5w6fw6q 3025 9 ONSD ONSD NNP cord-006870-f5w6fw6q 3025 10 and and CC cord-006870-f5w6fw6q 3025 11 ventricular ventricular JJ cord-006870-f5w6fw6q 3025 12 ICP ICP NNP cord-006870-f5w6fw6q 3025 13 and and CC cord-006870-f5w6fw6q 3025 14 defined define VBD cord-006870-f5w6fw6q 3025 15 an an DT cord-006870-f5w6fw6q 3025 16 optimal optimal JJ cord-006870-f5w6fw6q 3025 17 cut cut NN cord-006870-f5w6fw6q 3025 18 - - HYPH cord-006870-f5w6fw6q 3025 19 off off RP cord-006870-f5w6fw6q 3025 20 point point NN cord-006870-f5w6fw6q 3025 21 for for IN cord-006870-f5w6fw6q 3025 22 identifying identify VBG cord-006870-f5w6fw6q 3025 23 increased increase VBN cord-006870-f5w6fw6q 3025 24 ICP ICP NNP cord-006870-f5w6fw6q 3025 25 ( ( -LRB- cord-006870-f5w6fw6q 3025 26 IICP IICP NNP cord-006870-f5w6fw6q 3025 27 ) ) -RRB- cord-006870-f5w6fw6q 3025 28 in in IN cord-006870-f5w6fw6q 3025 29 Korean korean JJ cord-006870-f5w6fw6q 3025 30 adults adult NNS cord-006870-f5w6fw6q 3025 31 with with IN cord-006870-f5w6fw6q 3025 32 brain brain NN cord-006870-f5w6fw6q 3025 33 lesions lesion NNS cord-006870-f5w6fw6q 3025 34 . . . cord-006870-f5w6fw6q 3026 1 This this DT cord-006870-f5w6fw6q 3026 2 prospective prospective JJ cord-006870-f5w6fw6q 3026 3 study study NN cord-006870-f5w6fw6q 3026 4 included include VBD cord-006870-f5w6fw6q 3026 5 patients patient NNS cord-006870-f5w6fw6q 3026 6 who who WP cord-006870-f5w6fw6q 3026 7 required require VBD cord-006870-f5w6fw6q 3026 8 an an DT cord-006870-f5w6fw6q 3026 9 external external JJ cord-006870-f5w6fw6q 3026 10 ventricular ventricular JJ cord-006870-f5w6fw6q 3026 11 drainage drainage NN cord-006870-f5w6fw6q 3026 12 ( ( -LRB- cord-006870-f5w6fw6q 3026 13 EVD EVD NNP cord-006870-f5w6fw6q 3026 14 ) ) -RRB- cord-006870-f5w6fw6q 3026 15 catheter catheter NN cord-006870-f5w6fw6q 3026 16 for for IN cord-006870-f5w6fw6q 3026 17 ICP ICP NNP cord-006870-f5w6fw6q 3026 18 control control NN cord-006870-f5w6fw6q 3026 19 . . . cord-006870-f5w6fw6q 3027 1 IICP IICP NNP cord-006870-f5w6fw6q 3027 2 was be VBD cord-006870-f5w6fw6q 3027 3 defined define VBN cord-006870-f5w6fw6q 3027 4 as as IN cord-006870-f5w6fw6q 3027 5 an an DT cord-006870-f5w6fw6q 3027 6 opening opening NN cord-006870-f5w6fw6q 3027 7 pressure pressure NN cord-006870-f5w6fw6q 3027 8 over over IN cord-006870-f5w6fw6q 3028 1 20 20 CD cord-006870-f5w6fw6q 3028 2 mmHg mmHg NNS cord-006870-f5w6fw6q 3028 3 . . . cord-006870-f5w6fw6q 3028 4 ONSD ONSD NNP cord-006870-f5w6fw6q 3028 5 was be VBD cord-006870-f5w6fw6q 3028 6 measured measure VBN cord-006870-f5w6fw6q 3028 7 using use VBG cord-006870-f5w6fw6q 3028 8 a a DT cord-006870-f5w6fw6q 3028 9 13 13 CD cord-006870-f5w6fw6q 3028 10 MHz MHz NNS cord-006870-f5w6fw6q 3028 11 US US NNP cord-006870-f5w6fw6q 3028 12 probe probe NN cord-006870-f5w6fw6q 3028 13 before before IN cord-006870-f5w6fw6q 3028 14 the the DT cord-006870-f5w6fw6q 3028 15 procedure procedure NN cord-006870-f5w6fw6q 3028 16 . . . cord-006870-f5w6fw6q 3029 1 Linear linear JJ cord-006870-f5w6fw6q 3029 2 regression regression NN cord-006870-f5w6fw6q 3029 3 analysis analysis NN cord-006870-f5w6fw6q 3029 4 and and CC cord-006870-f5w6fw6q 3029 5 receiver receiver NN cord-006870-f5w6fw6q 3029 6 operator operator NN cord-006870-f5w6fw6q 3029 7 characteristic characteristic NN cord-006870-f5w6fw6q 3029 8 ( ( -LRB- cord-006870-f5w6fw6q 3029 9 ROC ROC NNP cord-006870-f5w6fw6q 3029 10 ) ) -RRB- cord-006870-f5w6fw6q 3029 11 curve curve NN cord-006870-f5w6fw6q 3029 12 were be VBD cord-006870-f5w6fw6q 3029 13 used use VBN cord-006870-f5w6fw6q 3029 14 to to TO cord-006870-f5w6fw6q 3029 15 assess assess VB cord-006870-f5w6fw6q 3029 16 the the DT cord-006870-f5w6fw6q 3029 17 association association NN cord-006870-f5w6fw6q 3029 18 between between IN cord-006870-f5w6fw6q 3029 19 ONSD ONSD NNP cord-006870-f5w6fw6q 3029 20 and and CC cord-006870-f5w6fw6q 3029 21 ICP ICP NNP cord-006870-f5w6fw6q 3029 22 . . . cord-006870-f5w6fw6q 3030 1 Optimal optimal JJ cord-006870-f5w6fw6q 3030 2 cut cut VB cord-006870-f5w6fw6q 3030 3 - - HYPH cord-006870-f5w6fw6q 3030 4 off off RP cord-006870-f5w6fw6q 3030 5 value value NN cord-006870-f5w6fw6q 3030 6 for for IN cord-006870-f5w6fw6q 3030 7 identifying identify VBG cord-006870-f5w6fw6q 3030 8 IICP IICP NNP cord-006870-f5w6fw6q 3030 9 was be VBD cord-006870-f5w6fw6q 3030 10 defined define VBN cord-006870-f5w6fw6q 3030 11 . . . cord-006870-f5w6fw6q 3031 1 A a DT cord-006870-f5w6fw6q 3031 2 total total NN cord-006870-f5w6fw6q 3031 3 of of IN cord-006870-f5w6fw6q 3031 4 62 62 CD cord-006870-f5w6fw6q 3031 5 patients patient NNS cord-006870-f5w6fw6q 3031 6 who who WP cord-006870-f5w6fw6q 3031 7 underwent undergo VBD cord-006870-f5w6fw6q 3031 8 ONSD ONSD NNP cord-006870-f5w6fw6q 3031 9 measurement measurement NN cord-006870-f5w6fw6q 3031 10 with with IN cord-006870-f5w6fw6q 3031 11 simultaneous simultaneous JJ cord-006870-f5w6fw6q 3031 12 EVD EVD NNP cord-006870-f5w6fw6q 3031 13 catheter catheter NN cord-006870-f5w6fw6q 3031 14 placement placement NN cord-006870-f5w6fw6q 3031 15 were be VBD cord-006870-f5w6fw6q 3031 16 enrolled enrol VBN cord-006870-f5w6fw6q 3031 17 in in IN cord-006870-f5w6fw6q 3031 18 this this DT cord-006870-f5w6fw6q 3031 19 study study NN cord-006870-f5w6fw6q 3031 20 . . . cord-006870-f5w6fw6q 3032 1 Thirty thirty CD cord-006870-f5w6fw6q 3032 2 - - HYPH cord-006870-f5w6fw6q 3032 3 two two CD cord-006870-f5w6fw6q 3032 4 patients patient NNS cord-006870-f5w6fw6q 3032 5 ( ( -LRB- cord-006870-f5w6fw6q 3032 6 51.6 51.6 CD cord-006870-f5w6fw6q 3032 7 % % NN cord-006870-f5w6fw6q 3032 8 ) ) -RRB- cord-006870-f5w6fw6q 3032 9 were be VBD cord-006870-f5w6fw6q 3032 10 found find VBN cord-006870-f5w6fw6q 3032 11 to to TO cord-006870-f5w6fw6q 3032 12 have have VB cord-006870-f5w6fw6q 3032 13 IICP IICP NNP cord-006870-f5w6fw6q 3032 14 . . . cord-006870-f5w6fw6q 3033 1 ONSD ONSD NNP cord-006870-f5w6fw6q 3033 2 in in IN cord-006870-f5w6fw6q 3033 3 patients patient NNS cord-006870-f5w6fw6q 3033 4 with with IN cord-006870-f5w6fw6q 3033 5 IICP IICP NNP cord-006870-f5w6fw6q 3033 6 ( ( -LRB- cord-006870-f5w6fw6q 3033 7 5.95 5.95 CD cord-006870-f5w6fw6q 3033 8 ± ± CD cord-006870-f5w6fw6q 3033 9 0.25 0.25 CD cord-006870-f5w6fw6q 3033 10 mm mm NNP cord-006870-f5w6fw6q 3033 11 ) ) -RRB- cord-006870-f5w6fw6q 3033 12 was be VBD cord-006870-f5w6fw6q 3033 13 significantly significantly RB cord-006870-f5w6fw6q 3033 14 higher high JJR cord-006870-f5w6fw6q 3033 15 than than IN cord-006870-f5w6fw6q 3033 16 in in IN cord-006870-f5w6fw6q 3033 17 those those DT cord-006870-f5w6fw6q 3033 18 without without IN cord-006870-f5w6fw6q 3033 19 IICP IICP NNP cord-006870-f5w6fw6q 3033 20 ( ( -LRB- cord-006870-f5w6fw6q 3033 21 5.17 5.17 CD cord-006870-f5w6fw6q 3033 22 ± ± CD cord-006870-f5w6fw6q 3033 23 0.57 0.57 CD cord-006870-f5w6fw6q 3033 24 mm mm NN cord-006870-f5w6fw6q 3033 25 ) ) -RRB- cord-006870-f5w6fw6q 3034 1 ( ( -LRB- cord-006870-f5w6fw6q 3034 2 P p NN cord-006870-f5w6fw6q 3034 3 5.6 5.6 CD cord-006870-f5w6fw6q 3034 4 mm mm NNS cord-006870-f5w6fw6q 3034 5 disclosed disclose VBD cord-006870-f5w6fw6q 3034 6 a a DT cord-006870-f5w6fw6q 3034 7 sensitivity sensitivity NN cord-006870-f5w6fw6q 3034 8 of of IN cord-006870-f5w6fw6q 3034 9 93.75 93.75 CD cord-006870-f5w6fw6q 3034 10 % % NN cord-006870-f5w6fw6q 3034 11 and and CC cord-006870-f5w6fw6q 3034 12 a a DT cord-006870-f5w6fw6q 3034 13 specificity specificity NN cord-006870-f5w6fw6q 3034 14 of of IN cord-006870-f5w6fw6q 3034 15 86.67 86.67 CD cord-006870-f5w6fw6q 3034 16 % % NN cord-006870-f5w6fw6q 3034 17 for for IN cord-006870-f5w6fw6q 3034 18 identifying identify VBG cord-006870-f5w6fw6q 3034 19 IICP IICP NNP cord-006870-f5w6fw6q 3034 20 . . . cord-006870-f5w6fw6q 3035 1 ONSD ONSD NNP cord-006870-f5w6fw6q 3035 2 as as IN cord-006870-f5w6fw6q 3035 3 seen see VBN cord-006870-f5w6fw6q 3035 4 on on IN cord-006870-f5w6fw6q 3035 5 bedside bedside NN cord-006870-f5w6fw6q 3035 6 US US NNP cord-006870-f5w6fw6q 3035 7 correlated correlate VBD cord-006870-f5w6fw6q 3035 8 well well RB cord-006870-f5w6fw6q 3035 9 with with IN cord-006870-f5w6fw6q 3035 10 directly directly RB cord-006870-f5w6fw6q 3035 11 measured measure VBN cord-006870-f5w6fw6q 3035 12 ICP ICP NNP cord-006870-f5w6fw6q 3035 13 in in IN cord-006870-f5w6fw6q 3035 14 Korean korean JJ cord-006870-f5w6fw6q 3035 15 adults adult NNS cord-006870-f5w6fw6q 3035 16 with with IN cord-006870-f5w6fw6q 3035 17 brain brain NN cord-006870-f5w6fw6q 3035 18 lesions lesion NNS cord-006870-f5w6fw6q 3035 19 . . . cord-006870-f5w6fw6q 3036 1 The the DT cord-006870-f5w6fw6q 3036 2 optimal optimal JJ cord-006870-f5w6fw6q 3036 3 cut cut VB cord-006870-f5w6fw6q 3036 4 - - HYPH cord-006870-f5w6fw6q 3036 5 off off RP cord-006870-f5w6fw6q 3036 6 point point NN cord-006870-f5w6fw6q 3036 7 of of IN cord-006870-f5w6fw6q 3036 8 ONSD ONSD NNP cord-006870-f5w6fw6q 3036 9 for for IN cord-006870-f5w6fw6q 3036 10 detecting detect VBG cord-006870-f5w6fw6q 3036 11 IICP IICP NNP cord-006870-f5w6fw6q 3036 12 was be VBD cord-006870-f5w6fw6q 3036 13 5.6 5.6 CD cord-006870-f5w6fw6q 3036 14 mm mm NNS cord-006870-f5w6fw6q 3036 15 . . . cord-006870-f5w6fw6q 3037 1 Impaired impair VBN cord-006870-f5w6fw6q 3037 2 cerebral cerebral JJ cord-006870-f5w6fw6q 3037 3 autoregulation autoregulation NN cord-006870-f5w6fw6q 3037 4 following follow VBG cord-006870-f5w6fw6q 3037 5 neurological neurological JJ cord-006870-f5w6fw6q 3037 6 insult insult NN cord-006870-f5w6fw6q 3037 7 has have VBZ cord-006870-f5w6fw6q 3037 8 been be VBN cord-006870-f5w6fw6q 3037 9 established establish VBN cord-006870-f5w6fw6q 3037 10 as as IN cord-006870-f5w6fw6q 3037 11 a a DT cord-006870-f5w6fw6q 3037 12 strong strong JJ cord-006870-f5w6fw6q 3037 13 predictor predictor NN cord-006870-f5w6fw6q 3037 14 of of IN cord-006870-f5w6fw6q 3037 15 clinical clinical JJ cord-006870-f5w6fw6q 3037 16 outcome outcome NN cord-006870-f5w6fw6q 3037 17 . . . cord-006870-f5w6fw6q 3038 1 Hypothermia hypothermia NN cord-006870-f5w6fw6q 3038 2 may may MD cord-006870-f5w6fw6q 3038 3 offer offer VB cord-006870-f5w6fw6q 3038 4 autoregulatory autoregulatory NN cord-006870-f5w6fw6q 3038 5 protection protection NN cord-006870-f5w6fw6q 3038 6 in in IN cord-006870-f5w6fw6q 3038 7 these these DT cord-006870-f5w6fw6q 3038 8 patients patient NNS cord-006870-f5w6fw6q 3038 9 , , , cord-006870-f5w6fw6q 3038 10 although although IN cord-006870-f5w6fw6q 3038 11 the the DT cord-006870-f5w6fw6q 3038 12 effect effect NN cord-006870-f5w6fw6q 3038 13 of of IN cord-006870-f5w6fw6q 3038 14 body body NN cord-006870-f5w6fw6q 3038 15 temperature temperature NN cord-006870-f5w6fw6q 3038 16 on on IN cord-006870-f5w6fw6q 3038 17 autoregulatory autoregulatory NN cord-006870-f5w6fw6q 3038 18 status status NN cord-006870-f5w6fw6q 3038 19 is be VBZ cord-006870-f5w6fw6q 3038 20 unclear unclear JJ cord-006870-f5w6fw6q 3038 21 . . . cord-006870-f5w6fw6q 3039 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 3039 2 analysis analysis NN cord-006870-f5w6fw6q 3039 3 of of IN cord-006870-f5w6fw6q 3039 4 data datum NNS cord-006870-f5w6fw6q 3039 5 from from IN cord-006870-f5w6fw6q 3039 6 an an DT cord-006870-f5w6fw6q 3039 7 ongoing ongoing JJ cord-006870-f5w6fw6q 3039 8 prospective prospective JJ cord-006870-f5w6fw6q 3039 9 study study NN cord-006870-f5w6fw6q 3039 10 to to TO cord-006870-f5w6fw6q 3039 11 evaluate evaluate VB cord-006870-f5w6fw6q 3039 12 multimodal multimodal NN cord-006870-f5w6fw6q 3039 13 monitoring monitoring NN cord-006870-f5w6fw6q 3039 14 using use VBG cord-006870-f5w6fw6q 3039 15 near near IN cord-006870-f5w6fw6q 3039 16 infrared infrared JJ cord-006870-f5w6fw6q 3039 17 spectroscopy spectroscopy NN cord-006870-f5w6fw6q 3039 18 ( ( -LRB- cord-006870-f5w6fw6q 3039 19 NIRS NIRS NNP cord-006870-f5w6fw6q 3039 20 ) ) -RRB- cord-006870-f5w6fw6q 3039 21 for for IN cord-006870-f5w6fw6q 3039 22 bedside bedside NN cord-006870-f5w6fw6q 3039 23 measurement measurement NN cord-006870-f5w6fw6q 3039 24 of of IN cord-006870-f5w6fw6q 3039 25 autoregulation autoregulation NN cord-006870-f5w6fw6q 3039 26 . . . cord-006870-f5w6fw6q 3040 1 Ninety ninety CD cord-006870-f5w6fw6q 3040 2 - - HYPH cord-006870-f5w6fw6q 3040 3 one one CD cord-006870-f5w6fw6q 3040 4 comatose comatose JJ cord-006870-f5w6fw6q 3040 5 patients patient NNS cord-006870-f5w6fw6q 3040 6 ( ( -LRB- cord-006870-f5w6fw6q 3040 7 GCS GCS NNP cord-006870-f5w6fw6q 3040 8 < < XX cord-006870-f5w6fw6q 3040 9 8) 8) NNP cord-006870-f5w6fw6q 3040 10 were be VBD cord-006870-f5w6fw6q 3040 11 continuously continuously RB cord-006870-f5w6fw6q 3040 12 monitored monitor VBN cord-006870-f5w6fw6q 3040 13 for for IN cord-006870-f5w6fw6q 3040 14 up up IN cord-006870-f5w6fw6q 3040 15 to to TO cord-006870-f5w6fw6q 3040 16 three three CD cord-006870-f5w6fw6q 3040 17 days day NNS cord-006870-f5w6fw6q 3040 18 . . . cord-006870-f5w6fw6q 3041 1 NIRS nirs NN cord-006870-f5w6fw6q 3041 2 derived derive VBD cord-006870-f5w6fw6q 3041 3 cerebral cerebral JJ cord-006870-f5w6fw6q 3041 4 oximetry oximetry NN cord-006870-f5w6fw6q 3041 5 index index NN cord-006870-f5w6fw6q 3041 6 ( ( -LRB- cord-006870-f5w6fw6q 3041 7 COx COx NNS cord-006870-f5w6fw6q 3041 8 ) ) -RRB- cord-006870-f5w6fw6q 3041 9 was be VBD cord-006870-f5w6fw6q 3041 10 used use VBN cord-006870-f5w6fw6q 3041 11 as as IN cord-006870-f5w6fw6q 3041 12 a a DT cord-006870-f5w6fw6q 3041 13 marker marker NN cord-006870-f5w6fw6q 3041 14 of of IN cord-006870-f5w6fw6q 3041 15 autoregulation autoregulation NN cord-006870-f5w6fw6q 3041 16 . . . cord-006870-f5w6fw6q 3042 1 COx COx NNS cord-006870-f5w6fw6q 3042 2 was be VBD cord-006870-f5w6fw6q 3042 3 calculated calculate VBN cord-006870-f5w6fw6q 3042 4 as as IN cord-006870-f5w6fw6q 3042 5 a a DT cord-006870-f5w6fw6q 3042 6 moving move VBG cord-006870-f5w6fw6q 3042 7 , , , cord-006870-f5w6fw6q 3042 8 linear linear JJ cord-006870-f5w6fw6q 3042 9 correlation correlation NN cord-006870-f5w6fw6q 3042 10 coefficient coefficient NN cord-006870-f5w6fw6q 3042 11 between between IN cord-006870-f5w6fw6q 3042 12 regional regional JJ cord-006870-f5w6fw6q 3042 13 cerebral cerebral JJ cord-006870-f5w6fw6q 3042 14 oxygenation oxygenation NN cord-006870-f5w6fw6q 3042 15 saturation saturation NN cord-006870-f5w6fw6q 3042 16 and and CC cord-006870-f5w6fw6q 3042 17 MAP map NN cord-006870-f5w6fw6q 3042 18 . . . cord-006870-f5w6fw6q 3043 1 Autoregulation Autoregulation NNP cord-006870-f5w6fw6q 3043 2 improves improve VBZ cord-006870-f5w6fw6q 3043 3 as as IN cord-006870-f5w6fw6q 3043 4 COx COx NNS cord-006870-f5w6fw6q 3043 5 values value NNS cord-006870-f5w6fw6q 3043 6 approach approach VBP cord-006870-f5w6fw6q 3043 7 0 0 CD cord-006870-f5w6fw6q 3043 8 , , , cord-006870-f5w6fw6q 3043 9 and and CC cord-006870-f5w6fw6q 3043 10 is be VBZ cord-006870-f5w6fw6q 3043 11 impaired impair VBN cord-006870-f5w6fw6q 3043 12 as as IN cord-006870-f5w6fw6q 3043 13 values value NNS cord-006870-f5w6fw6q 3043 14 approach approach VBP cord-006870-f5w6fw6q 3043 15 1 1 CD cord-006870-f5w6fw6q 3043 16 . . . cord-006870-f5w6fw6q 3044 1 Patients patient NNS cord-006870-f5w6fw6q 3044 2 were be VBD cord-006870-f5w6fw6q 3044 3 grouped group VBN cord-006870-f5w6fw6q 3044 4 by by IN cord-006870-f5w6fw6q 3044 5 trend trend NN cord-006870-f5w6fw6q 3044 6 in in IN cord-006870-f5w6fw6q 3044 7 temperature temperature NN cord-006870-f5w6fw6q 3044 8 seen see VBN cord-006870-f5w6fw6q 3044 9 over over IN cord-006870-f5w6fw6q 3044 10 the the DT cord-006870-f5w6fw6q 3044 11 monitoring monitoring NN cord-006870-f5w6fw6q 3044 12 period period NN cord-006870-f5w6fw6q 3044 13 : : : cord-006870-f5w6fw6q 3045 1 no no DT cord-006870-f5w6fw6q 3045 2 change change NN cord-006870-f5w6fw6q 3045 3 ( ( -LRB- cord-006870-f5w6fw6q 3045 4 < < NNP cord-006870-f5w6fw6q 3045 5 1oC 1oc CD cord-006870-f5w6fw6q 3045 6 temperature temperature NN cord-006870-f5w6fw6q 3045 7 change change NN cord-006870-f5w6fw6q 3045 8 , , , cord-006870-f5w6fw6q 3045 9 n=12 n=12 NNP cord-006870-f5w6fw6q 3045 10 ) ) -RRB- cord-006870-f5w6fw6q 3045 11 , , , cord-006870-f5w6fw6q 3045 12 increase increase NN cord-006870-f5w6fw6q 3045 13 ( ( -LRB- cord-006870-f5w6fw6q 3045 14 n=6 n=6 NNP cord-006870-f5w6fw6q 3045 15 ) ) -RRB- cord-006870-f5w6fw6q 3045 16 , , , cord-006870-f5w6fw6q 3045 17 decrease decrease NN cord-006870-f5w6fw6q 3045 18 ( ( -LRB- cord-006870-f5w6fw6q 3045 19 n=7 n=7 NNS cord-006870-f5w6fw6q 3045 20 ) ) -RRB- cord-006870-f5w6fw6q 3045 21 , , , cord-006870-f5w6fw6q 3045 22 increase increase NN cord-006870-f5w6fw6q 3045 23 followed follow VBN cord-006870-f5w6fw6q 3045 24 by by IN cord-006870-f5w6fw6q 3045 25 decrease decrease NN cord-006870-f5w6fw6q 3045 26 ( ( -LRB- cord-006870-f5w6fw6q 3045 27 n=7 n=7 NNS cord-006870-f5w6fw6q 3045 28 ) ) -RRB- cord-006870-f5w6fw6q 3045 29 , , , cord-006870-f5w6fw6q 3045 30 decrease decrease NN cord-006870-f5w6fw6q 3045 31 followed follow VBN cord-006870-f5w6fw6q 3045 32 by by IN cord-006870-f5w6fw6q 3045 33 increase increase NN cord-006870-f5w6fw6q 3045 34 ( ( -LRB- cord-006870-f5w6fw6q 3045 35 n=6 n=6 NNP cord-006870-f5w6fw6q 3045 36 ) ) -RRB- cord-006870-f5w6fw6q 3045 37 , , , cord-006870-f5w6fw6q 3045 38 and and CC cord-006870-f5w6fw6q 3045 39 fluctuating fluctuate VBG cord-006870-f5w6fw6q 3045 40 ( ( -LRB- cord-006870-f5w6fw6q 3045 41 n=53 n=53 NNS cord-006870-f5w6fw6q 3045 42 ) ) -RRB- cord-006870-f5w6fw6q 3045 43 . . . cord-006870-f5w6fw6q 3046 1 We -PRON- PRP cord-006870-f5w6fw6q 3046 2 performed perform VBD cord-006870-f5w6fw6q 3046 3 multivariable multivariable JJ cord-006870-f5w6fw6q 3046 4 logistic logistic JJ cord-006870-f5w6fw6q 3046 5 regression regression NN cord-006870-f5w6fw6q 3046 6 analysis analysis NN cord-006870-f5w6fw6q 3046 7 to to TO cord-006870-f5w6fw6q 3046 8 assess assess VB cord-006870-f5w6fw6q 3046 9 the the DT cord-006870-f5w6fw6q 3046 10 association association NN cord-006870-f5w6fw6q 3046 11 between between IN cord-006870-f5w6fw6q 3046 12 temperature temperature NN cord-006870-f5w6fw6q 3046 13 and and CC cord-006870-f5w6fw6q 3046 14 outcomes outcome NNS cord-006870-f5w6fw6q 3046 15 . . . cord-006870-f5w6fw6q 3047 1 The the DT cord-006870-f5w6fw6q 3047 2 association association NN cord-006870-f5w6fw6q 3047 3 between between IN cord-006870-f5w6fw6q 3047 4 hourly hourly JJ cord-006870-f5w6fw6q 3047 5 temperature temperature NN cord-006870-f5w6fw6q 3047 6 and and CC cord-006870-f5w6fw6q 3047 7 COx COx NNS cord-006870-f5w6fw6q 3047 8 was be VBD cord-006870-f5w6fw6q 3047 9 assessed assess VBN cord-006870-f5w6fw6q 3047 10 using use VBG cord-006870-f5w6fw6q 3047 11 mixed mixed JJ cord-006870-f5w6fw6q 3047 12 random random JJ cord-006870-f5w6fw6q 3047 13 effects effect NNS cord-006870-f5w6fw6q 3047 14 models model NNS cord-006870-f5w6fw6q 3047 15 with with IN cord-006870-f5w6fw6q 3047 16 random random JJ cord-006870-f5w6fw6q 3047 17 intercept intercept NN cord-006870-f5w6fw6q 3047 18 . . . cord-006870-f5w6fw6q 3048 1 In in IN cord-006870-f5w6fw6q 3048 2 patients patient NNS cord-006870-f5w6fw6q 3048 3 showing show VBG cord-006870-f5w6fw6q 3048 4 a a DT cord-006870-f5w6fw6q 3048 5 sustained sustained JJ cord-006870-f5w6fw6q 3048 6 increase increase NN cord-006870-f5w6fw6q 3048 7 or or CC cord-006870-f5w6fw6q 3048 8 decrease decrease NN cord-006870-f5w6fw6q 3048 9 in in IN cord-006870-f5w6fw6q 3048 10 temperature temperature NN cord-006870-f5w6fw6q 3048 11 , , , cord-006870-f5w6fw6q 3048 12 a a DT cord-006870-f5w6fw6q 3048 13 linear linear JJ cord-006870-f5w6fw6q 3048 14 relationship relationship NN cord-006870-f5w6fw6q 3048 15 between between IN cord-006870-f5w6fw6q 3048 16 temperature temperature NN cord-006870-f5w6fw6q 3048 17 and and CC cord-006870-f5w6fw6q 3048 18 COx COx NNS cord-006870-f5w6fw6q 3048 19 was be VBD cord-006870-f5w6fw6q 3048 20 seen see VBN cord-006870-f5w6fw6q 3048 21 ; ; : cord-006870-f5w6fw6q 3048 22 for for IN cord-006870-f5w6fw6q 3048 23 every every DT cord-006870-f5w6fw6q 3048 24 1oC 1oc CD cord-006870-f5w6fw6q 3048 25 increase increase NN cord-006870-f5w6fw6q 3048 26 or or CC cord-006870-f5w6fw6q 3048 27 decrease decrease NN cord-006870-f5w6fw6q 3048 28 in in IN cord-006870-f5w6fw6q 3048 29 temperature temperature NN cord-006870-f5w6fw6q 3048 30 , , , cord-006870-f5w6fw6q 3048 31 COx COx NNS cord-006870-f5w6fw6q 3048 32 changed change VBN cord-006870-f5w6fw6q 3048 33 by by IN cord-006870-f5w6fw6q 3048 34 0.045±0.010 0.045±0.010 CD cord-006870-f5w6fw6q 3049 1 ( ( -LRB- cord-006870-f5w6fw6q 3049 2 p<0.001 p<0.001 JJ cord-006870-f5w6fw6q 3049 3 ) ) -RRB- cord-006870-f5w6fw6q 3049 4 and and CC cord-006870-f5w6fw6q 3049 5 -0.020±0.018 -0.020±0.018 NN cord-006870-f5w6fw6q 3050 1 ( ( -LRB- cord-006870-f5w6fw6q 3050 2 p=0.15 p=0.15 NNP cord-006870-f5w6fw6q 3050 3 ) ) -RRB- cord-006870-f5w6fw6q 3050 4 , , , cord-006870-f5w6fw6q 3050 5 respectively respectively RB cord-006870-f5w6fw6q 3050 6 , , , cord-006870-f5w6fw6q 3050 7 after after IN cord-006870-f5w6fw6q 3050 8 adjusting adjust VBG cord-006870-f5w6fw6q 3050 9 for for IN cord-006870-f5w6fw6q 3050 10 pCO2 pCO2 NNP cord-006870-f5w6fw6q 3050 11 , , , cord-006870-f5w6fw6q 3050 12 haemoglobin haemoglobin NN cord-006870-f5w6fw6q 3050 13 , , , cord-006870-f5w6fw6q 3050 14 MAP MAP NNP cord-006870-f5w6fw6q 3050 15 and and CC cord-006870-f5w6fw6q 3050 16 temperature temperature NN cord-006870-f5w6fw6q 3050 17 probe probe NN cord-006870-f5w6fw6q 3050 18 location location NN cord-006870-f5w6fw6q 3050 19 . . . cord-006870-f5w6fw6q 3051 1 Mean mean JJ cord-006870-f5w6fw6q 3051 2 temperature temperature NN cord-006870-f5w6fw6q 3051 3 changes change NNS cord-006870-f5w6fw6q 3051 4 over over IN cord-006870-f5w6fw6q 3051 5 the the DT cord-006870-f5w6fw6q 3051 6 monitoring monitoring NN cord-006870-f5w6fw6q 3051 7 period period NN cord-006870-f5w6fw6q 3051 8 for for IN cord-006870-f5w6fw6q 3051 9 these these DT cord-006870-f5w6fw6q 3051 10 groups group NNS cord-006870-f5w6fw6q 3051 11 were be VBD cord-006870-f5w6fw6q 3051 12 2.52±1.07oC 2.52±1.07oc CD cord-006870-f5w6fw6q 3051 13 and and CC cord-006870-f5w6fw6q 3051 14 -1.77±1.13oC -1.77±1.13oc ADD cord-006870-f5w6fw6q 3051 15 , , , cord-006870-f5w6fw6q 3051 16 respectively respectively RB cord-006870-f5w6fw6q 3051 17 . . . cord-006870-f5w6fw6q 3052 1 COx COx NNS cord-006870-f5w6fw6q 3052 2 did do VBD cord-006870-f5w6fw6q 3052 3 not not RB cord-006870-f5w6fw6q 3052 4 change change VB cord-006870-f5w6fw6q 3052 5 significantly significantly RB cord-006870-f5w6fw6q 3052 6 in in IN cord-006870-f5w6fw6q 3052 7 other other JJ cord-006870-f5w6fw6q 3052 8 groups group NNS cord-006870-f5w6fw6q 3052 9 . . . cord-006870-f5w6fw6q 3053 1 There there EX cord-006870-f5w6fw6q 3053 2 was be VBD cord-006870-f5w6fw6q 3053 3 no no DT cord-006870-f5w6fw6q 3053 4 significant significant JJ cord-006870-f5w6fw6q 3053 5 difference difference NN cord-006870-f5w6fw6q 3053 6 in in IN cord-006870-f5w6fw6q 3053 7 mortality mortality NN cord-006870-f5w6fw6q 3053 8 or or CC cord-006870-f5w6fw6q 3053 9 poor poor JJ cord-006870-f5w6fw6q 3053 10 outcome outcome NN cord-006870-f5w6fw6q 3054 1 ( ( -LRB- cord-006870-f5w6fw6q 3054 2 mRS mRS `` cord-006870-f5w6fw6q 3054 3 4 4 CD cord-006870-f5w6fw6q 3054 4 - - SYM cord-006870-f5w6fw6q 3054 5 6 6 CD cord-006870-f5w6fw6q 3054 6 ) ) -RRB- cord-006870-f5w6fw6q 3054 7 at at IN cord-006870-f5w6fw6q 3054 8 discharge discharge NN cord-006870-f5w6fw6q 3054 9 and and CC cord-006870-f5w6fw6q 3054 10 3 3 CD cord-006870-f5w6fw6q 3054 11 , , , cord-006870-f5w6fw6q 3054 12 6 6 CD cord-006870-f5w6fw6q 3054 13 , , , cord-006870-f5w6fw6q 3054 14 or or CC cord-006870-f5w6fw6q 3054 15 12 12 CD cord-006870-f5w6fw6q 3054 16 months month NNS cord-006870-f5w6fw6q 3054 17 between between IN cord-006870-f5w6fw6q 3054 18 patients patient NNS cord-006870-f5w6fw6q 3054 19 in in IN cord-006870-f5w6fw6q 3054 20 each each DT cord-006870-f5w6fw6q 3054 21 group group NN cord-006870-f5w6fw6q 3054 22 . . . cord-006870-f5w6fw6q 3055 1 In in IN cord-006870-f5w6fw6q 3055 2 acute acute JJ cord-006870-f5w6fw6q 3055 3 coma coma NN cord-006870-f5w6fw6q 3055 4 patients patient NNS cord-006870-f5w6fw6q 3055 5 in in IN cord-006870-f5w6fw6q 3055 6 the the DT cord-006870-f5w6fw6q 3055 7 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3055 8 care care NNP cord-006870-f5w6fw6q 3055 9 unit unit NN cord-006870-f5w6fw6q 3055 10 , , , cord-006870-f5w6fw6q 3055 11 increasing increase VBG cord-006870-f5w6fw6q 3055 12 body body NN cord-006870-f5w6fw6q 3055 13 temperature temperature NN cord-006870-f5w6fw6q 3055 14 is be VBZ cord-006870-f5w6fw6q 3055 15 associated associate VBN cord-006870-f5w6fw6q 3055 16 with with IN cord-006870-f5w6fw6q 3055 17 worsening worsen VBG cord-006870-f5w6fw6q 3055 18 cerebral cerebral JJ cord-006870-f5w6fw6q 3055 19 autoregulation autoregulation NN cord-006870-f5w6fw6q 3055 20 as as IN cord-006870-f5w6fw6q 3055 21 measured measure VBN cord-006870-f5w6fw6q 3055 22 by by IN cord-006870-f5w6fw6q 3055 23 COx COx NNS cord-006870-f5w6fw6q 3055 24 . . . cord-006870-f5w6fw6q 3056 1 The the DT cord-006870-f5w6fw6q 3056 2 historical historical JJ cord-006870-f5w6fw6q 3056 3 tradition tradition NN cord-006870-f5w6fw6q 3056 4 of of IN cord-006870-f5w6fw6q 3056 5 examining examine VBG cord-006870-f5w6fw6q 3056 6 the the DT cord-006870-f5w6fw6q 3056 7 pupillary pupillary JJ cord-006870-f5w6fw6q 3056 8 light light JJ cord-006870-f5w6fw6q 3056 9 reflex reflex NN cord-006870-f5w6fw6q 3056 10 ( ( -LRB- cord-006870-f5w6fw6q 3056 11 PLR PLR NNP cord-006870-f5w6fw6q 3056 12 ) ) -RRB- cord-006870-f5w6fw6q 3056 13 required require VBD cord-006870-f5w6fw6q 3056 14 the the DT cord-006870-f5w6fw6q 3056 15 examiner examiner NN cord-006870-f5w6fw6q 3056 16 to to TO cord-006870-f5w6fw6q 3056 17 score score VB cord-006870-f5w6fw6q 3056 18 the the DT cord-006870-f5w6fw6q 3056 19 size size NN cord-006870-f5w6fw6q 3056 20 and and CC cord-006870-f5w6fw6q 3056 21 reactivity reactivity NN cord-006870-f5w6fw6q 3056 22 of of IN cord-006870-f5w6fw6q 3056 23 the the DT cord-006870-f5w6fw6q 3056 24 pupil pupil NN cord-006870-f5w6fw6q 3056 25 . . . cord-006870-f5w6fw6q 3057 1 A a DT cord-006870-f5w6fw6q 3057 2 change change NN cord-006870-f5w6fw6q 3057 3 in in IN cord-006870-f5w6fw6q 3057 4 the the DT cord-006870-f5w6fw6q 3057 5 PLR plr NN cord-006870-f5w6fw6q 3057 6 from from IN cord-006870-f5w6fw6q 3057 7 brisk brisk JJ cord-006870-f5w6fw6q 3057 8 to to IN cord-006870-f5w6fw6q 3057 9 sluggish sluggish JJ cord-006870-f5w6fw6q 3057 10 or or CC cord-006870-f5w6fw6q 3057 11 fixed fix VBN cord-006870-f5w6fw6q 3057 12 may may MD cord-006870-f5w6fw6q 3057 13 be be VB cord-006870-f5w6fw6q 3057 14 a a DT cord-006870-f5w6fw6q 3057 15 marker marker NN cord-006870-f5w6fw6q 3057 16 of of IN cord-006870-f5w6fw6q 3057 17 a a DT cord-006870-f5w6fw6q 3057 18 pathological pathological JJ cord-006870-f5w6fw6q 3057 19 process process NN cord-006870-f5w6fw6q 3057 20 and and CC cord-006870-f5w6fw6q 3057 21 a a DT cord-006870-f5w6fw6q 3057 22 need need NN cord-006870-f5w6fw6q 3057 23 for for IN cord-006870-f5w6fw6q 3057 24 intervention intervention NN cord-006870-f5w6fw6q 3057 25 . . . cord-006870-f5w6fw6q 3058 1 The the DT cord-006870-f5w6fw6q 3058 2 PLR plr NN cord-006870-f5w6fw6q 3058 3 has have VBZ cord-006870-f5w6fw6q 3058 4 been be VBN cord-006870-f5w6fw6q 3058 5 difficult difficult JJ cord-006870-f5w6fw6q 3058 6 to to TO cord-006870-f5w6fw6q 3058 7 quantify quantify VB cord-006870-f5w6fw6q 3058 8 and and CC cord-006870-f5w6fw6q 3058 9 has have VBZ cord-006870-f5w6fw6q 3058 10 poor poor JJ cord-006870-f5w6fw6q 3058 11 inter inter JJ cord-006870-f5w6fw6q 3058 12 - - JJ cord-006870-f5w6fw6q 3058 13 rater rater JJ cord-006870-f5w6fw6q 3058 14 reliability reliability NN cord-006870-f5w6fw6q 3058 15 . . . cord-006870-f5w6fw6q 3059 1 Handheld Handheld NNP cord-006870-f5w6fw6q 3059 2 pupillometry pupillometry NNP cord-006870-f5w6fw6q 3059 3 provides provide VBZ cord-006870-f5w6fw6q 3059 4 several several JJ cord-006870-f5w6fw6q 3059 5 novel novel JJ cord-006870-f5w6fw6q 3059 6 measures measure NNS cord-006870-f5w6fw6q 3059 7 , , , cord-006870-f5w6fw6q 3059 8 such such JJ cord-006870-f5w6fw6q 3059 9 as as IN cord-006870-f5w6fw6q 3059 10 the the DT cord-006870-f5w6fw6q 3059 11 neurological neurological JJ cord-006870-f5w6fw6q 3059 12 pupillary pupillary JJ cord-006870-f5w6fw6q 3059 13 index index NNP cord-006870-f5w6fw6q 3059 14 ™ ™ '' cord-006870-f5w6fw6q 3059 15 ( ( -LRB- cord-006870-f5w6fw6q 3059 16 NPi NPi NNP cord-006870-f5w6fw6q 3059 17 ) ) -RRB- cord-006870-f5w6fw6q 3059 18 and and CC cord-006870-f5w6fw6q 3059 19 constriction constriction NN cord-006870-f5w6fw6q 3059 20 velocity velocity NN cord-006870-f5w6fw6q 3059 21 ( ( -LRB- cord-006870-f5w6fw6q 3059 22 CV cv NN cord-006870-f5w6fw6q 3059 23 ) ) -RRB- cord-006870-f5w6fw6q 3059 24 that that WDT cord-006870-f5w6fw6q 3059 25 may may MD cord-006870-f5w6fw6q 3059 26 be be VB cord-006870-f5w6fw6q 3059 27 more more RBR cord-006870-f5w6fw6q 3059 28 quantifiable quantifiable JJ cord-006870-f5w6fw6q 3059 29 than than IN cord-006870-f5w6fw6q 3059 30 the the DT cord-006870-f5w6fw6q 3059 31 PLR plr NN cord-006870-f5w6fw6q 3059 32 . . . cord-006870-f5w6fw6q 3060 1 The the DT cord-006870-f5w6fw6q 3060 2 purpose purpose NN cord-006870-f5w6fw6q 3060 3 of of IN cord-006870-f5w6fw6q 3060 4 this this DT cord-006870-f5w6fw6q 3060 5 analysis analysis NN cord-006870-f5w6fw6q 3060 6 is be VBZ cord-006870-f5w6fw6q 3060 7 to to TO cord-006870-f5w6fw6q 3060 8 examine examine VB cord-006870-f5w6fw6q 3060 9 the the DT cord-006870-f5w6fw6q 3060 10 relationship relationship NN cord-006870-f5w6fw6q 3060 11 between between IN cord-006870-f5w6fw6q 3060 12 CV CV NNP cord-006870-f5w6fw6q 3060 13 and and CC cord-006870-f5w6fw6q 3060 14 NPi NPi NNPS cord-006870-f5w6fw6q 3060 15 in in IN cord-006870-f5w6fw6q 3060 16 neurologically neurologically RB cord-006870-f5w6fw6q 3060 17 injured injure VBN cord-006870-f5w6fw6q 3060 18 patients patient NNS cord-006870-f5w6fw6q 3060 19 . . . cord-006870-f5w6fw6q 3061 1 The the DT cord-006870-f5w6fw6q 3061 2 END end NN cord-006870-f5w6fw6q 3061 3 - - HYPH cord-006870-f5w6fw6q 3061 4 PANIC panic NN cord-006870-f5w6fw6q 3061 5 Registry Registry NNP cord-006870-f5w6fw6q 3061 6 is be VBZ cord-006870-f5w6fw6q 3061 7 a a DT cord-006870-f5w6fw6q 3061 8 prospective prospective JJ cord-006870-f5w6fw6q 3061 9 registry registry NN cord-006870-f5w6fw6q 3061 10 of of IN cord-006870-f5w6fw6q 3061 11 pupillometer pupillometer JJ cord-006870-f5w6fw6q 3061 12 values value NNS cord-006870-f5w6fw6q 3061 13 and and CC cord-006870-f5w6fw6q 3061 14 variables variable NNS cord-006870-f5w6fw6q 3061 15 associated associate VBN cord-006870-f5w6fw6q 3061 16 with with IN cord-006870-f5w6fw6q 3061 17 intracranial intracranial JJ cord-006870-f5w6fw6q 3061 18 dynamics dynamic NNS cord-006870-f5w6fw6q 3061 19 ( ( -LRB- cord-006870-f5w6fw6q 3061 20 e.g. e.g. RB cord-006870-f5w6fw6q 3061 21 , , , cord-006870-f5w6fw6q 3061 22 ICP ICP NNP cord-006870-f5w6fw6q 3061 23 ) ) -RRB- cord-006870-f5w6fw6q 3061 24 . . . cord-006870-f5w6fw6q 3062 1 This this DT cord-006870-f5w6fw6q 3062 2 analysis analysis NN cord-006870-f5w6fw6q 3062 3 from from IN cord-006870-f5w6fw6q 3062 4 946 946 CD cord-006870-f5w6fw6q 3062 5 adult adult NN cord-006870-f5w6fw6q 3062 6 ( ( -LRB- cord-006870-f5w6fw6q 3062 7 over over IN cord-006870-f5w6fw6q 3062 8 18 18 CD cord-006870-f5w6fw6q 3062 9 years year NNS cord-006870-f5w6fw6q 3062 10 ) ) -RRB- cord-006870-f5w6fw6q 3062 11 patients patient NNS cord-006870-f5w6fw6q 3062 12 from from IN cord-006870-f5w6fw6q 3062 13 2 2 CD cord-006870-f5w6fw6q 3062 14 hospitals hospital NNS cord-006870-f5w6fw6q 3062 15 includes include VBZ cord-006870-f5w6fw6q 3062 16 42,568 42,568 CD cord-006870-f5w6fw6q 3062 17 pupillometer pupillometer NN cord-006870-f5w6fw6q 3062 18 readings reading NNS cord-006870-f5w6fw6q 3062 19 ; ; : cord-006870-f5w6fw6q 3062 20 left left JJ cord-006870-f5w6fw6q 3062 21 eye eye NN cord-006870-f5w6fw6q 3062 22 ( ( -LRB- cord-006870-f5w6fw6q 3062 23 20,943 20,943 CD cord-006870-f5w6fw6q 3062 24 ) ) -RRB- cord-006870-f5w6fw6q 3062 25 , , , cord-006870-f5w6fw6q 3062 26 and and CC cord-006870-f5w6fw6q 3062 27 right right JJ cord-006870-f5w6fw6q 3062 28 eye eye NN cord-006870-f5w6fw6q 3062 29 ( ( -LRB- cord-006870-f5w6fw6q 3062 30 21,625 21,625 CD cord-006870-f5w6fw6q 3062 31 ) ) -RRB- cord-006870-f5w6fw6q 3062 32 . . . cord-006870-f5w6fw6q 3063 1 Subjects subject NNS cord-006870-f5w6fw6q 3063 2 had have VBD cord-006870-f5w6fw6q 3063 3 a a DT cord-006870-f5w6fw6q 3063 4 mean mean JJ cord-006870-f5w6fw6q 3063 5 age age NN cord-006870-f5w6fw6q 3063 6 of of IN cord-006870-f5w6fw6q 3063 7 57.9 57.9 CD cord-006870-f5w6fw6q 3063 8 yrs yr NNS cord-006870-f5w6fw6q 3063 9 and and CC cord-006870-f5w6fw6q 3063 10 48.1 48.1 CD cord-006870-f5w6fw6q 3063 11 % % NN cord-006870-f5w6fw6q 3063 12 were be VBD cord-006870-f5w6fw6q 3063 13 male male JJ cord-006870-f5w6fw6q 3063 14 . . . cord-006870-f5w6fw6q 3064 1 The the DT cord-006870-f5w6fw6q 3064 2 primary primary JJ cord-006870-f5w6fw6q 3064 3 admission admission NN cord-006870-f5w6fw6q 3064 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 3064 5 included include VBD cord-006870-f5w6fw6q 3064 6 neoplasm neoplasm NN cord-006870-f5w6fw6q 3064 7 ( ( -LRB- cord-006870-f5w6fw6q 3064 8 241 241 CD cord-006870-f5w6fw6q 3064 9 ) ) -RRB- cord-006870-f5w6fw6q 3064 10 , , , cord-006870-f5w6fw6q 3064 11 ischemic ischemic JJ cord-006870-f5w6fw6q 3064 12 stroke stroke NN cord-006870-f5w6fw6q 3064 13 ( ( -LRB- cord-006870-f5w6fw6q 3064 14 169 169 CD cord-006870-f5w6fw6q 3064 15 ) ) -RRB- cord-006870-f5w6fw6q 3064 16 , , , cord-006870-f5w6fw6q 3064 17 SAH SAH NNP cord-006870-f5w6fw6q 3064 18 ( ( -LRB- cord-006870-f5w6fw6q 3064 19 82 82 CD cord-006870-f5w6fw6q 3064 20 ) ) -RRB- cord-006870-f5w6fw6q 3064 21 , , , cord-006870-f5w6fw6q 3064 22 ICH ICH NNP cord-006870-f5w6fw6q 3064 23 ( ( -LRB- cord-006870-f5w6fw6q 3064 24 81 81 CD cord-006870-f5w6fw6q 3064 25 ) ) -RRB- cord-006870-f5w6fw6q 3064 26 , , , cord-006870-f5w6fw6q 3064 27 TBI TBI NNP cord-006870-f5w6fw6q 3064 28 ( ( -LRB- cord-006870-f5w6fw6q 3064 29 9 9 CD cord-006870-f5w6fw6q 3064 30 ) ) -RRB- cord-006870-f5w6fw6q 3064 31 , , , cord-006870-f5w6fw6q 3064 32 and and CC cord-006870-f5w6fw6q 3064 33 other other JJ cord-006870-f5w6fw6q 3064 34 ( ( -LRB- cord-006870-f5w6fw6q 3064 35 364 364 CD cord-006870-f5w6fw6q 3064 36 ) ) -RRB- cord-006870-f5w6fw6q 3064 37 . . . cord-006870-f5w6fw6q 3065 1 The the DT cord-006870-f5w6fw6q 3065 2 left left JJ cord-006870-f5w6fw6q 3065 3 eye eye NN cord-006870-f5w6fw6q 3065 4 mean mean NN cord-006870-f5w6fw6q 3065 5 / / SYM cord-006870-f5w6fw6q 3065 6 s.d s.d NNP cord-006870-f5w6fw6q 3065 7 . . NNP cord-006870-f5w6fw6q 3065 8 CV CV NNP cord-006870-f5w6fw6q 3065 9 ( ( -LRB- cord-006870-f5w6fw6q 3065 10 1.6/0.9 1.6/0.9 CD cord-006870-f5w6fw6q 3065 11 ) ) -RRB- cord-006870-f5w6fw6q 3065 12 NPi NPi NNS cord-006870-f5w6fw6q 3065 13 ( ( -LRB- cord-006870-f5w6fw6q 3065 14 4.1/0.9 4.1/0.9 CD cord-006870-f5w6fw6q 3065 15 ) ) -RRB- cord-006870-f5w6fw6q 3065 16 and and CC cord-006870-f5w6fw6q 3065 17 Size size NN cord-006870-f5w6fw6q 3065 18 ( ( -LRB- cord-006870-f5w6fw6q 3065 19 3.5/1.2 3.5/1.2 CD cord-006870-f5w6fw6q 3065 20 ) ) -RRB- cord-006870-f5w6fw6q 3065 21 were be VBD cord-006870-f5w6fw6q 3065 22 similar similar JJ cord-006870-f5w6fw6q 3065 23 to to IN cord-006870-f5w6fw6q 3065 24 the the DT cord-006870-f5w6fw6q 3065 25 right right JJ cord-006870-f5w6fw6q 3065 26 eye eye NN cord-006870-f5w6fw6q 3065 27 CV cv NN cord-006870-f5w6fw6q 3065 28 ( ( -LRB- cord-006870-f5w6fw6q 3065 29 1.6/0.9 1.6/0.9 CD cord-006870-f5w6fw6q 3065 30 ) ) -RRB- cord-006870-f5w6fw6q 3065 31 NPi NPi NNS cord-006870-f5w6fw6q 3065 32 ( ( -LRB- cord-006870-f5w6fw6q 3065 33 4.1/0.9 4.1/0.9 CD cord-006870-f5w6fw6q 3065 34 ) ) -RRB- cord-006870-f5w6fw6q 3065 35 and and CC cord-006870-f5w6fw6q 3065 36 size size NN cord-006870-f5w6fw6q 3065 37 ( ( -LRB- cord-006870-f5w6fw6q 3065 38 3.5/1.2 3.5/1.2 CD cord-006870-f5w6fw6q 3065 39 ) ) -RRB- cord-006870-f5w6fw6q 3065 40 ; ; : cord-006870-f5w6fw6q 3065 41 statistically statistically RB cord-006870-f5w6fw6q 3065 42 significant significant JJ cord-006870-f5w6fw6q 3065 43 difference difference NN cord-006870-f5w6fw6q 3065 44 related relate VBN cord-006870-f5w6fw6q 3065 45 to to IN cord-006870-f5w6fw6q 3065 46 large large JJ cord-006870-f5w6fw6q 3065 47 sample sample NN cord-006870-f5w6fw6q 3065 48 size size NN cord-006870-f5w6fw6q 3065 49 . . . cord-006870-f5w6fw6q 3066 1 The the DT cord-006870-f5w6fw6q 3066 2 correlation correlation NN cord-006870-f5w6fw6q 3066 3 between between IN cord-006870-f5w6fw6q 3066 4 left left JJ cord-006870-f5w6fw6q 3066 5 eye eye NN cord-006870-f5w6fw6q 3066 6 CV cv NN cord-006870-f5w6fw6q 3066 7 and and CC cord-006870-f5w6fw6q 3066 8 NPi NPi NNP cord-006870-f5w6fw6q 3066 9 ( ( -LRB- cord-006870-f5w6fw6q 3066 10 r2=0.068 r2=0.068 NNP cord-006870-f5w6fw6q 3066 11 , , , cord-006870-f5w6fw6q 3066 12 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 3066 13 ) ) -RRB- cord-006870-f5w6fw6q 3066 14 was be VBD cord-006870-f5w6fw6q 3066 15 significantly significantly RB cord-006870-f5w6fw6q 3066 16 improved improve VBN cord-006870-f5w6fw6q 3066 17 after after IN cord-006870-f5w6fw6q 3066 18 controlling control VBG cord-006870-f5w6fw6q 3066 19 for for IN cord-006870-f5w6fw6q 3066 20 size size NN cord-006870-f5w6fw6q 3066 21 ( ( -LRB- cord-006870-f5w6fw6q 3066 22 r2=0.67 r2=0.67 ADD cord-006870-f5w6fw6q 3066 23 , , , cord-006870-f5w6fw6q 3066 24 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 3066 25 ) ) -RRB- cord-006870-f5w6fw6q 3066 26 . . . cord-006870-f5w6fw6q 3067 1 The the DT cord-006870-f5w6fw6q 3067 2 correlation correlation NN cord-006870-f5w6fw6q 3067 3 between between IN cord-006870-f5w6fw6q 3067 4 right right JJ cord-006870-f5w6fw6q 3067 5 eye eye NN cord-006870-f5w6fw6q 3067 6 CV cv NN cord-006870-f5w6fw6q 3067 7 and and CC cord-006870-f5w6fw6q 3067 8 NPi NPi NNP cord-006870-f5w6fw6q 3067 9 ( ( -LRB- cord-006870-f5w6fw6q 3067 10 r2=0.048 r2=0.048 NNP cord-006870-f5w6fw6q 3067 11 , , , cord-006870-f5w6fw6q 3067 12 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 3067 13 ) ) -RRB- cord-006870-f5w6fw6q 3067 14 was be VBD cord-006870-f5w6fw6q 3067 15 significantly significantly RB cord-006870-f5w6fw6q 3067 16 improved improve VBN cord-006870-f5w6fw6q 3067 17 after after IN cord-006870-f5w6fw6q 3067 18 controlling control VBG cord-006870-f5w6fw6q 3067 19 for for IN cord-006870-f5w6fw6q 3067 20 size size NN cord-006870-f5w6fw6q 3067 21 ( ( -LRB- cord-006870-f5w6fw6q 3067 22 r2=0.67 r2=0.67 ADD cord-006870-f5w6fw6q 3067 23 , , , cord-006870-f5w6fw6q 3067 24 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 3067 25 ) ) -RRB- cord-006870-f5w6fw6q 3067 26 . . . cord-006870-f5w6fw6q 3068 1 Constriction constriction NN cord-006870-f5w6fw6q 3068 2 velocity velocity NN cord-006870-f5w6fw6q 3068 3 is be VBZ cord-006870-f5w6fw6q 3068 4 highly highly RB cord-006870-f5w6fw6q 3068 5 dependent dependent JJ cord-006870-f5w6fw6q 3068 6 on on IN cord-006870-f5w6fw6q 3068 7 size size NN cord-006870-f5w6fw6q 3068 8 of of IN cord-006870-f5w6fw6q 3068 9 the the DT cord-006870-f5w6fw6q 3068 10 pupil pupil NN cord-006870-f5w6fw6q 3068 11 . . . cord-006870-f5w6fw6q 3069 1 Further further JJ cord-006870-f5w6fw6q 3069 2 studies study NNS cord-006870-f5w6fw6q 3069 3 need need VBP cord-006870-f5w6fw6q 3069 4 to to TO cord-006870-f5w6fw6q 3069 5 be be VB cord-006870-f5w6fw6q 3069 6 undertaken undertake VBN cord-006870-f5w6fw6q 3069 7 to to TO cord-006870-f5w6fw6q 3069 8 determine determine VB cord-006870-f5w6fw6q 3069 9 the the DT cord-006870-f5w6fw6q 3069 10 sensitivity sensitivity NN cord-006870-f5w6fw6q 3069 11 and and CC cord-006870-f5w6fw6q 3069 12 specificity specificity NN cord-006870-f5w6fw6q 3069 13 of of IN cord-006870-f5w6fw6q 3069 14 abnormal abnormal JJ cord-006870-f5w6fw6q 3069 15 NPi NPi NNS cord-006870-f5w6fw6q 3069 16 and and CC cord-006870-f5w6fw6q 3069 17 CV CV NNP cord-006870-f5w6fw6q 3069 18 in in IN cord-006870-f5w6fw6q 3069 19 detecting detect VBG cord-006870-f5w6fw6q 3069 20 pathological pathological JJ cord-006870-f5w6fw6q 3069 21 processes process NNS cord-006870-f5w6fw6q 3069 22 such such JJ cord-006870-f5w6fw6q 3069 23 as as IN cord-006870-f5w6fw6q 3069 24 midline midline JJ cord-006870-f5w6fw6q 3069 25 shift shift NN cord-006870-f5w6fw6q 3069 26 or or CC cord-006870-f5w6fw6q 3069 27 3rd 3rd JJ cord-006870-f5w6fw6q 3069 28 nerve nerve NN cord-006870-f5w6fw6q 3069 29 compression compression NN cord-006870-f5w6fw6q 3069 30 that that WDT cord-006870-f5w6fw6q 3069 31 effect effect NN cord-006870-f5w6fw6q 3069 32 pupillary pupillary JJ cord-006870-f5w6fw6q 3069 33 reactivity reactivity NN cord-006870-f5w6fw6q 3069 34 . . . cord-006870-f5w6fw6q 3070 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 3070 2 injury injury NN cord-006870-f5w6fw6q 3070 3 is be VBZ cord-006870-f5w6fw6q 3070 4 increasingly increasingly RB cord-006870-f5w6fw6q 3070 5 described describe VBN cord-006870-f5w6fw6q 3070 6 in in IN cord-006870-f5w6fw6q 3070 7 adult adult NN cord-006870-f5w6fw6q 3070 8 recipients recipient NNS cord-006870-f5w6fw6q 3070 9 of of IN cord-006870-f5w6fw6q 3070 10 extracorporeal extracorporeal JJ cord-006870-f5w6fw6q 3070 11 membrane membrane NN cord-006870-f5w6fw6q 3070 12 oxygenation oxygenation NN cord-006870-f5w6fw6q 3070 13 ( ( -LRB- cord-006870-f5w6fw6q 3070 14 ECMO ECMO NNP cord-006870-f5w6fw6q 3070 15 ) ) -RRB- cord-006870-f5w6fw6q 3070 16 therapy therapy NN cord-006870-f5w6fw6q 3070 17 . . . cord-006870-f5w6fw6q 3071 1 We -PRON- PRP cord-006870-f5w6fw6q 3071 2 describe describe VBP cord-006870-f5w6fw6q 3071 3 the the DT cord-006870-f5w6fw6q 3071 4 association association NN cord-006870-f5w6fw6q 3071 5 between between IN cord-006870-f5w6fw6q 3071 6 regional regional JJ cord-006870-f5w6fw6q 3071 7 brain brain NN cord-006870-f5w6fw6q 3071 8 tissue tissue NN cord-006870-f5w6fw6q 3071 9 oxygenation oxygenation NN cord-006870-f5w6fw6q 3071 10 ( ( -LRB- cord-006870-f5w6fw6q 3071 11 rSO2 rSO2 NNP cord-006870-f5w6fw6q 3071 12 ) ) -RRB- cord-006870-f5w6fw6q 3071 13 measured measure VBN cord-006870-f5w6fw6q 3071 14 by by IN cord-006870-f5w6fw6q 3071 15 near near JJ cord-006870-f5w6fw6q 3071 16 infrared infrared JJ cord-006870-f5w6fw6q 3071 17 spectroscopy spectroscopy NN cord-006870-f5w6fw6q 3071 18 ( ( -LRB- cord-006870-f5w6fw6q 3071 19 NIRS NIRS NNP cord-006870-f5w6fw6q 3071 20 ) ) -RRB- cord-006870-f5w6fw6q 3071 21 , , , cord-006870-f5w6fw6q 3071 22 survival survival NN cord-006870-f5w6fw6q 3071 23 , , , cord-006870-f5w6fw6q 3071 24 and and CC cord-006870-f5w6fw6q 3071 25 cerebral cerebral JJ cord-006870-f5w6fw6q 3071 26 injury injury NN cord-006870-f5w6fw6q 3071 27 on on IN cord-006870-f5w6fw6q 3071 28 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 3071 29 . . . cord-006870-f5w6fw6q 3072 1 A a DT cord-006870-f5w6fw6q 3072 2 single single JJ cord-006870-f5w6fw6q 3072 3 - - HYPH cord-006870-f5w6fw6q 3072 4 center center NN cord-006870-f5w6fw6q 3072 5 retrospective retrospective JJ cord-006870-f5w6fw6q 3072 6 chart chart NN cord-006870-f5w6fw6q 3072 7 review review NN cord-006870-f5w6fw6q 3072 8 was be VBD cord-006870-f5w6fw6q 3072 9 conducted conduct VBN cord-006870-f5w6fw6q 3072 10 of of IN cord-006870-f5w6fw6q 3072 11 adult adult NN cord-006870-f5w6fw6q 3072 12 patients patient NNS cord-006870-f5w6fw6q 3072 13 who who WP cord-006870-f5w6fw6q 3072 14 underwent undergo VBD cord-006870-f5w6fw6q 3072 15 veno veno NNP cord-006870-f5w6fw6q 3072 16 - - HYPH cord-006870-f5w6fw6q 3072 17 arterial arterial JJ cord-006870-f5w6fw6q 3072 18 ( ( -LRB- cord-006870-f5w6fw6q 3072 19 VA VA NNP cord-006870-f5w6fw6q 3072 20 ) ) -RRB- cord-006870-f5w6fw6q 3072 21 ECMO ECMO NNP cord-006870-f5w6fw6q 3072 22 from from IN cord-006870-f5w6fw6q 3072 23 April April NNP cord-006870-f5w6fw6q 3072 24 2016 2016 CD cord-006870-f5w6fw6q 3072 25 to to IN cord-006870-f5w6fw6q 3072 26 October October NNP cord-006870-f5w6fw6q 3072 27 2016 2016 CD cord-006870-f5w6fw6q 3072 28 . . . cord-006870-f5w6fw6q 3073 1 All all DT cord-006870-f5w6fw6q 3073 2 patients patient NNS cord-006870-f5w6fw6q 3073 3 had have VBD cord-006870-f5w6fw6q 3073 4 received receive VBN cord-006870-f5w6fw6q 3073 5 NIRS NIRS NNP cord-006870-f5w6fw6q 3073 6 monitoring monitoring NN cord-006870-f5w6fw6q 3073 7 during during IN cord-006870-f5w6fw6q 3073 8 ECMO ECMO NNP cord-006870-f5w6fw6q 3073 9 therapy therapy NN cord-006870-f5w6fw6q 3073 10 . . . cord-006870-f5w6fw6q 3074 1 Baseline baseline JJ cord-006870-f5w6fw6q 3074 2 demographics demographic NNS cord-006870-f5w6fw6q 3074 3 , , , cord-006870-f5w6fw6q 3074 4 in in IN cord-006870-f5w6fw6q 3074 5 - - HYPH cord-006870-f5w6fw6q 3074 6 hospital hospital NN cord-006870-f5w6fw6q 3074 7 complications complication NNS cord-006870-f5w6fw6q 3074 8 , , , cord-006870-f5w6fw6q 3074 9 and and CC cord-006870-f5w6fw6q 3074 10 mortality mortality NN cord-006870-f5w6fw6q 3074 11 were be VBD cord-006870-f5w6fw6q 3074 12 recorded record VBN cord-006870-f5w6fw6q 3074 13 . . . cord-006870-f5w6fw6q 3075 1 Desaturations desaturation NNS cord-006870-f5w6fw6q 3075 2 of of IN cord-006870-f5w6fw6q 3075 3 rSO2 rSO2 NNP cord-006870-f5w6fw6q 3075 4 , , , cord-006870-f5w6fw6q 3075 5 defined define VBN cord-006870-f5w6fw6q 3075 6 as as IN cord-006870-f5w6fw6q 3075 7 decline decline NN cord-006870-f5w6fw6q 3075 8 > > NFP cord-006870-f5w6fw6q 3075 9 25 25 CD cord-006870-f5w6fw6q 3075 10 % % NN cord-006870-f5w6fw6q 3075 11 below below IN cord-006870-f5w6fw6q 3075 12 baseline baseline NN cord-006870-f5w6fw6q 3075 13 or or CC cord-006870-f5w6fw6q 3075 14 absolute absolute JJ cord-006870-f5w6fw6q 3075 15 value value NN cord-006870-f5w6fw6q 3075 16 < < XX cord-006870-f5w6fw6q 3075 17 40 40 CD cord-006870-f5w6fw6q 3075 18 , , , cord-006870-f5w6fw6q 3075 19 were be VBD cord-006870-f5w6fw6q 3075 20 recorded record VBN cord-006870-f5w6fw6q 3075 21 and and CC cord-006870-f5w6fw6q 3075 22 analyzed analyze VBN cord-006870-f5w6fw6q 3075 23 . . . cord-006870-f5w6fw6q 3076 1 Desaturation desaturation NN cord-006870-f5w6fw6q 3076 2 burden burden NN cord-006870-f5w6fw6q 3076 3 was be VBD cord-006870-f5w6fw6q 3076 4 calculated calculate VBN cord-006870-f5w6fw6q 3076 5 by by IN cord-006870-f5w6fw6q 3076 6 area area NN cord-006870-f5w6fw6q 3076 7 under under IN cord-006870-f5w6fw6q 3076 8 the the DT cord-006870-f5w6fw6q 3076 9 curve curve NN cord-006870-f5w6fw6q 3076 10 analysis analysis NN cord-006870-f5w6fw6q 3076 11 and and CC cord-006870-f5w6fw6q 3076 12 measured measure VBN cord-006870-f5w6fw6q 3076 13 by by IN cord-006870-f5w6fw6q 3076 14 rSO2*seconds rso2*second NNS cord-006870-f5w6fw6q 3076 15 . . . cord-006870-f5w6fw6q 3077 1 Eighteen eighteen JJ cord-006870-f5w6fw6q 3077 2 VA VA NNP cord-006870-f5w6fw6q 3077 3 ECMO ECMO NNP cord-006870-f5w6fw6q 3077 4 patients patient NNS cord-006870-f5w6fw6q 3077 5 ( ( -LRB- cord-006870-f5w6fw6q 3077 6 9 9 CD cord-006870-f5w6fw6q 3077 7 females female NNS cord-006870-f5w6fw6q 3077 8 ) ) -RRB- cord-006870-f5w6fw6q 3077 9 underwent undergo VBD cord-006870-f5w6fw6q 3077 10 NIRS NIRS NNP cord-006870-f5w6fw6q 3077 11 monitoring monitor VBG cord-006870-f5w6fw6q 3077 12 during during IN cord-006870-f5w6fw6q 3077 13 the the DT cord-006870-f5w6fw6q 3077 14 study study NN cord-006870-f5w6fw6q 3077 15 period period NN cord-006870-f5w6fw6q 3077 16 . . . cord-006870-f5w6fw6q 3078 1 Eleven eleven CD cord-006870-f5w6fw6q 3078 2 patients patient NNS cord-006870-f5w6fw6q 3078 3 experienced experience VBD cord-006870-f5w6fw6q 3078 4 desaturations desaturation NNS cord-006870-f5w6fw6q 3078 5 , , , cord-006870-f5w6fw6q 3078 6 while while IN cord-006870-f5w6fw6q 3078 7 7 7 CD cord-006870-f5w6fw6q 3078 8 did do VBD cord-006870-f5w6fw6q 3078 9 not not RB cord-006870-f5w6fw6q 3078 10 . . . cord-006870-f5w6fw6q 3079 1 Patients patient NNS cord-006870-f5w6fw6q 3079 2 with with IN cord-006870-f5w6fw6q 3079 3 desaturations desaturation NNS cord-006870-f5w6fw6q 3079 4 tended tend VBD cord-006870-f5w6fw6q 3079 5 to to TO cord-006870-f5w6fw6q 3079 6 be be VB cord-006870-f5w6fw6q 3079 7 younger young JJR cord-006870-f5w6fw6q 3079 8 ( ( -LRB- cord-006870-f5w6fw6q 3079 9 50.2 50.2 CD cord-006870-f5w6fw6q 3079 10 vs. vs. IN cord-006870-f5w6fw6q 3079 11 64.7 64.7 CD cord-006870-f5w6fw6q 3079 12 years year NNS cord-006870-f5w6fw6q 3079 13 old old JJ cord-006870-f5w6fw6q 3079 14 ) ) -RRB- cord-006870-f5w6fw6q 3079 15 , , , cord-006870-f5w6fw6q 3079 16 more more RBR cord-006870-f5w6fw6q 3079 17 likely likely JJ cord-006870-f5w6fw6q 3079 18 female female NN cord-006870-f5w6fw6q 3079 19 ( ( -LRB- cord-006870-f5w6fw6q 3079 20 8 8 CD cord-006870-f5w6fw6q 3079 21 vs. vs. NN cord-006870-f5w6fw6q 3079 22 1 1 CD cord-006870-f5w6fw6q 3079 23 ) ) -RRB- cord-006870-f5w6fw6q 3079 24 , , , cord-006870-f5w6fw6q 3079 25 had have VBD cord-006870-f5w6fw6q 3079 26 lower low JJR cord-006870-f5w6fw6q 3079 27 ejection ejection NN cord-006870-f5w6fw6q 3079 28 fraction fraction NN cord-006870-f5w6fw6q 3079 29 ( ( -LRB- cord-006870-f5w6fw6q 3079 30 28.6 28.6 CD cord-006870-f5w6fw6q 3079 31 % % NN cord-006870-f5w6fw6q 3079 32 vs. vs. CC cord-006870-f5w6fw6q 3079 33 46.4 46.4 CD cord-006870-f5w6fw6q 3079 34 % % NN cord-006870-f5w6fw6q 3079 35 ) ) -RRB- cord-006870-f5w6fw6q 3079 36 and and CC cord-006870-f5w6fw6q 3079 37 experienced experience VBD cord-006870-f5w6fw6q 3079 38 liver liver NN cord-006870-f5w6fw6q 3079 39 dysfunction dysfunction NN cord-006870-f5w6fw6q 3079 40 ( ( -LRB- cord-006870-f5w6fw6q 3079 41 7 7 CD cord-006870-f5w6fw6q 3079 42 patients patient NNS cord-006870-f5w6fw6q 3079 43 vs. vs. IN cord-006870-f5w6fw6q 3079 44 1 1 CD cord-006870-f5w6fw6q 3079 45 ) ) -RRB- cord-006870-f5w6fw6q 3079 46 . . . cord-006870-f5w6fw6q 3080 1 Patients patient NNS cord-006870-f5w6fw6q 3080 2 with with IN cord-006870-f5w6fw6q 3080 3 desaturations desaturation NNS cord-006870-f5w6fw6q 3080 4 were be VBD cord-006870-f5w6fw6q 3080 5 more more RBR cord-006870-f5w6fw6q 3080 6 likely likely JJ cord-006870-f5w6fw6q 3080 7 to to TO cord-006870-f5w6fw6q 3080 8 have have VB cord-006870-f5w6fw6q 3080 9 abnormalities abnormality NNS cord-006870-f5w6fw6q 3080 10 on on IN cord-006870-f5w6fw6q 3080 11 CT CT NNP cord-006870-f5w6fw6q 3080 12 scan scan NN cord-006870-f5w6fw6q 3080 13 ( ( -LRB- cord-006870-f5w6fw6q 3080 14 6 6 CD cord-006870-f5w6fw6q 3080 15 vs. vs. NN cord-006870-f5w6fw6q 3080 16 0 0 CD cord-006870-f5w6fw6q 3080 17 ) ) -RRB- cord-006870-f5w6fw6q 3080 18 . . . cord-006870-f5w6fw6q 3081 1 Eleven eleven CD cord-006870-f5w6fw6q 3081 2 of of IN cord-006870-f5w6fw6q 3081 3 the the DT cord-006870-f5w6fw6q 3081 4 18 18 CD cord-006870-f5w6fw6q 3081 5 patients patient NNS cord-006870-f5w6fw6q 3081 6 survived survive VBD cord-006870-f5w6fw6q 3081 7 to to TO cord-006870-f5w6fw6q 3081 8 discharge discharge VB cord-006870-f5w6fw6q 3081 9 . . . cord-006870-f5w6fw6q 3082 1 Survivors survivor NNS cord-006870-f5w6fw6q 3082 2 tended tend VBD cord-006870-f5w6fw6q 3082 3 to to TO cord-006870-f5w6fw6q 3082 4 be be VB cord-006870-f5w6fw6q 3082 5 younger young JJR cord-006870-f5w6fw6q 3082 6 ( ( -LRB- cord-006870-f5w6fw6q 3082 7 50.2 50.2 CD cord-006870-f5w6fw6q 3082 8 vs. vs. IN cord-006870-f5w6fw6q 3082 9 64.6 64.6 CD cord-006870-f5w6fw6q 3082 10 years year NNS cord-006870-f5w6fw6q 3082 11 old old JJ cord-006870-f5w6fw6q 3082 12 ) ) -RRB- cord-006870-f5w6fw6q 3082 13 and and CC cord-006870-f5w6fw6q 3082 14 had have VBD cord-006870-f5w6fw6q 3082 15 lower low JJR cord-006870-f5w6fw6q 3082 16 initial initial JJ cord-006870-f5w6fw6q 3082 17 ECMO ecmo NN cord-006870-f5w6fw6q 3082 18 sweep sweep NN cord-006870-f5w6fw6q 3082 19 ( ( -LRB- cord-006870-f5w6fw6q 3082 20 4.1 4.1 CD cord-006870-f5w6fw6q 3082 21 vs. vs. CC cord-006870-f5w6fw6q 3082 22 6.7 6.7 CD cord-006870-f5w6fw6q 3082 23 ) ) -RRB- cord-006870-f5w6fw6q 3082 24 . . . cord-006870-f5w6fw6q 3083 1 Survivors survivor NNS cord-006870-f5w6fw6q 3083 2 had have VBD cord-006870-f5w6fw6q 3083 3 lower low JJR cord-006870-f5w6fw6q 3083 4 baseline baseline JJ cord-006870-f5w6fw6q 3083 5 rSO2 rSO2 NNP cord-006870-f5w6fw6q 3083 6 values value NNS cord-006870-f5w6fw6q 3083 7 at at IN cord-006870-f5w6fw6q 3083 8 the the DT cord-006870-f5w6fw6q 3083 9 beginning beginning NN cord-006870-f5w6fw6q 3083 10 of of IN cord-006870-f5w6fw6q 3083 11 NIRS NIRS NNP cord-006870-f5w6fw6q 3083 12 monitoring monitoring NN cord-006870-f5w6fw6q 3083 13 ( ( -LRB- cord-006870-f5w6fw6q 3083 14 right right JJ cord-006870-f5w6fw6q 3083 15 -57 -57 NNP cord-006870-f5w6fw6q 3083 16 vs. vs. IN cord-006870-f5w6fw6q 3083 17 65 65 CD cord-006870-f5w6fw6q 3083 18 , , , cord-006870-f5w6fw6q 3083 19 left leave VBD cord-006870-f5w6fw6q 3083 20 -57 -57 NNP cord-006870-f5w6fw6q 3083 21 vs. vs. CC cord-006870-f5w6fw6q 3083 22 68 68 CD cord-006870-f5w6fw6q 3083 23 ) ) -RRB- cord-006870-f5w6fw6q 3083 24 , , , cord-006870-f5w6fw6q 3083 25 fewer few JJR cord-006870-f5w6fw6q 3083 26 desaturation desaturation NN cord-006870-f5w6fw6q 3083 27 events event NNS cord-006870-f5w6fw6q 3083 28 ( ( -LRB- cord-006870-f5w6fw6q 3083 29 7 7 CD cord-006870-f5w6fw6q 3083 30 vs. vs. NN cord-006870-f5w6fw6q 3083 31 14 14 CD cord-006870-f5w6fw6q 3083 32 ) ) -RRB- cord-006870-f5w6fw6q 3083 33 , , , cord-006870-f5w6fw6q 3083 34 lower low JJR cord-006870-f5w6fw6q 3083 35 desaturation desaturation NN cord-006870-f5w6fw6q 3083 36 burden burden NN cord-006870-f5w6fw6q 3083 37 , , , cord-006870-f5w6fw6q 3083 38 and and CC cord-006870-f5w6fw6q 3083 39 spent spend VBD cord-006870-f5w6fw6q 3083 40 less less JJR cord-006870-f5w6fw6q 3083 41 overall overall JJ cord-006870-f5w6fw6q 3083 42 time time NN cord-006870-f5w6fw6q 3083 43 desaturating desaturate VBG cord-006870-f5w6fw6q 3083 44 ( ( -LRB- cord-006870-f5w6fw6q 3083 45 1:21 1:21 CD cord-006870-f5w6fw6q 3083 46 vs. vs. JJ cord-006870-f5w6fw6q 3083 47 3:09 3:09 CD cord-006870-f5w6fw6q 3083 48 hours hour NNS cord-006870-f5w6fw6q 3083 49 ) ) -RRB- cord-006870-f5w6fw6q 3083 50 . . . cord-006870-f5w6fw6q 3084 1 Desaturation Desaturation NNP cord-006870-f5w6fw6q 3084 2 on on IN cord-006870-f5w6fw6q 3084 3 NIRS NIRS NNP cord-006870-f5w6fw6q 3084 4 may may MD cord-006870-f5w6fw6q 3084 5 be be VB cord-006870-f5w6fw6q 3084 6 correlated correlate VBN cord-006870-f5w6fw6q 3084 7 with with IN cord-006870-f5w6fw6q 3084 8 cerebral cerebral JJ cord-006870-f5w6fw6q 3084 9 injury injury NN cord-006870-f5w6fw6q 3084 10 in in IN cord-006870-f5w6fw6q 3084 11 the the DT cord-006870-f5w6fw6q 3084 12 adult adult NN cord-006870-f5w6fw6q 3084 13 VA VA NNP cord-006870-f5w6fw6q 3084 14 ECMO ECMO NNP cord-006870-f5w6fw6q 3084 15 population population NN cord-006870-f5w6fw6q 3084 16 and and CC cord-006870-f5w6fw6q 3084 17 may may MD cord-006870-f5w6fw6q 3084 18 have have VB cord-006870-f5w6fw6q 3084 19 utility utility NN cord-006870-f5w6fw6q 3084 20 in in IN cord-006870-f5w6fw6q 3084 21 triggering trigger VBG cord-006870-f5w6fw6q 3084 22 clinical clinical JJ cord-006870-f5w6fw6q 3084 23 investigation investigation NN cord-006870-f5w6fw6q 3084 24 or or CC cord-006870-f5w6fw6q 3084 25 determining determine VBG cord-006870-f5w6fw6q 3084 26 prognosis prognosis NN cord-006870-f5w6fw6q 3084 27 . . . cord-006870-f5w6fw6q 3085 1 Further further JJ cord-006870-f5w6fw6q 3085 2 studies study NNS cord-006870-f5w6fw6q 3085 3 in in IN cord-006870-f5w6fw6q 3085 4 larger large JJR cord-006870-f5w6fw6q 3085 5 patient patient JJ cord-006870-f5w6fw6q 3085 6 populations population NNS cord-006870-f5w6fw6q 3085 7 are be VBP cord-006870-f5w6fw6q 3085 8 needed need VBN cord-006870-f5w6fw6q 3085 9 to to TO cord-006870-f5w6fw6q 3085 10 determine determine VB cord-006870-f5w6fw6q 3085 11 its -PRON- PRP$ cord-006870-f5w6fw6q 3085 12 reliability reliability NN cord-006870-f5w6fw6q 3085 13 and and CC cord-006870-f5w6fw6q 3085 14 accuracy accuracy NN cord-006870-f5w6fw6q 3085 15 . . . cord-006870-f5w6fw6q 3086 1 Pressure pressure NN cord-006870-f5w6fw6q 3086 2 reactivity reactivity NN cord-006870-f5w6fw6q 3086 3 index index NN cord-006870-f5w6fw6q 3086 4 ( ( -LRB- cord-006870-f5w6fw6q 3086 5 PRx PRx NNP cord-006870-f5w6fw6q 3086 6 ) ) -RRB- cord-006870-f5w6fw6q 3086 7 is be VBZ cord-006870-f5w6fw6q 3086 8 the the DT cord-006870-f5w6fw6q 3086 9 most most RBS cord-006870-f5w6fw6q 3086 10 validated validate VBN cord-006870-f5w6fw6q 3086 11 index index NN cord-006870-f5w6fw6q 3086 12 to to TO cord-006870-f5w6fw6q 3086 13 measure measure VB cord-006870-f5w6fw6q 3086 14 cerebrovascular cerebrovascular JJ cord-006870-f5w6fw6q 3086 15 reactivity reactivity NN cord-006870-f5w6fw6q 3086 16 in in IN cord-006870-f5w6fw6q 3086 17 patients patient NNS cord-006870-f5w6fw6q 3086 18 after after IN cord-006870-f5w6fw6q 3086 19 traumatic traumatic JJ cord-006870-f5w6fw6q 3086 20 brain brain NN cord-006870-f5w6fw6q 3086 21 injury injury NN cord-006870-f5w6fw6q 3086 22 . . . cord-006870-f5w6fw6q 3087 1 The the DT cord-006870-f5w6fw6q 3087 2 aim aim NN cord-006870-f5w6fw6q 3087 3 of of IN cord-006870-f5w6fw6q 3087 4 this this DT cord-006870-f5w6fw6q 3087 5 study study NN cord-006870-f5w6fw6q 3087 6 is be VBZ cord-006870-f5w6fw6q 3087 7 to to TO cord-006870-f5w6fw6q 3087 8 identify identify VB cord-006870-f5w6fw6q 3087 9 the the DT cord-006870-f5w6fw6q 3087 10 natural natural JJ cord-006870-f5w6fw6q 3087 11 history history NN cord-006870-f5w6fw6q 3087 12 of of IN cord-006870-f5w6fw6q 3087 13 cerebral cerebral JJ cord-006870-f5w6fw6q 3087 14 autoregulation autoregulation NN cord-006870-f5w6fw6q 3087 15 measured measure VBN cord-006870-f5w6fw6q 3087 16 by by IN cord-006870-f5w6fw6q 3087 17 PRx PRx NNS cord-006870-f5w6fw6q 3087 18 in in IN cord-006870-f5w6fw6q 3087 19 various various JJ cord-006870-f5w6fw6q 3087 20 forms form NNS cord-006870-f5w6fw6q 3087 21 of of IN cord-006870-f5w6fw6q 3087 22 brain brain NN cord-006870-f5w6fw6q 3087 23 injury injury NN cord-006870-f5w6fw6q 3087 24 to to TO cord-006870-f5w6fw6q 3087 25 monitor monitor VB cord-006870-f5w6fw6q 3087 26 restoration restoration NN cord-006870-f5w6fw6q 3087 27 or or CC cord-006870-f5w6fw6q 3087 28 not not RB cord-006870-f5w6fw6q 3087 29 of of IN cord-006870-f5w6fw6q 3087 30 cerebral cerebral JJ cord-006870-f5w6fw6q 3087 31 vasomotor vasomotor NN cord-006870-f5w6fw6q 3087 32 reactivity reactivity NN cord-006870-f5w6fw6q 3087 33 in in IN cord-006870-f5w6fw6q 3087 34 the the DT cord-006870-f5w6fw6q 3087 35 acute acute JJ cord-006870-f5w6fw6q 3087 36 phase phase NN cord-006870-f5w6fw6q 3087 37 . . . cord-006870-f5w6fw6q 3088 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 3088 2 analysis analysis NN cord-006870-f5w6fw6q 3088 3 of of IN cord-006870-f5w6fw6q 3088 4 data datum NNS cord-006870-f5w6fw6q 3088 5 from from IN cord-006870-f5w6fw6q 3088 6 ongoing ongoing JJ cord-006870-f5w6fw6q 3088 7 prospective prospective JJ cord-006870-f5w6fw6q 3088 8 study study NN cord-006870-f5w6fw6q 3088 9 to to TO cord-006870-f5w6fw6q 3088 10 evaluate evaluate VB cord-006870-f5w6fw6q 3088 11 multimodal multimodal NN cord-006870-f5w6fw6q 3088 12 monitoring monitoring NN cord-006870-f5w6fw6q 3088 13 using use VBG cord-006870-f5w6fw6q 3088 14 PRx PRx NNS cord-006870-f5w6fw6q 3088 15 for for IN cord-006870-f5w6fw6q 3088 16 the the DT cord-006870-f5w6fw6q 3088 17 measurement measurement NN cord-006870-f5w6fw6q 3088 18 of of IN cord-006870-f5w6fw6q 3088 19 cerebral cerebral JJ cord-006870-f5w6fw6q 3088 20 autoregulation autoregulation NN cord-006870-f5w6fw6q 3088 21 at at IN cord-006870-f5w6fw6q 3088 22 the the DT cord-006870-f5w6fw6q 3088 23 bedside bedside NN cord-006870-f5w6fw6q 3088 24 . . . cord-006870-f5w6fw6q 3089 1 Thirty thirty CD cord-006870-f5w6fw6q 3089 2 comatose comatose JJ cord-006870-f5w6fw6q 3089 3 patients patient NNS cord-006870-f5w6fw6q 3089 4 ( ( -LRB- cord-006870-f5w6fw6q 3089 5 Glasgow Glasgow NNP cord-006870-f5w6fw6q 3089 6 Coma Coma NNP cord-006870-f5w6fw6q 3089 7 Scal Scal NNP cord-006870-f5w6fw6q 3089 8 used use VBD cord-006870-f5w6fw6q 3089 9 as as IN cord-006870-f5w6fw6q 3089 10 a a DT cord-006870-f5w6fw6q 3089 11 marker marker NN cord-006870-f5w6fw6q 3089 12 of of IN cord-006870-f5w6fw6q 3089 13 autoregulation autoregulation NN cord-006870-f5w6fw6q 3089 14 . . . cord-006870-f5w6fw6q 3090 1 PRx PRx NNS cord-006870-f5w6fw6q 3090 2 was be VBD cord-006870-f5w6fw6q 3090 3 calculated calculate VBN cord-006870-f5w6fw6q 3090 4 as as IN cord-006870-f5w6fw6q 3090 5 a a DT cord-006870-f5w6fw6q 3090 6 moving move VBG cord-006870-f5w6fw6q 3090 7 , , , cord-006870-f5w6fw6q 3090 8 linear linear JJ cord-006870-f5w6fw6q 3090 9 correlation correlation NN cord-006870-f5w6fw6q 3090 10 coefficient coefficient NN cord-006870-f5w6fw6q 3090 11 between between IN cord-006870-f5w6fw6q 3090 12 ICP ICP NNP cord-006870-f5w6fw6q 3090 13 and and CC cord-006870-f5w6fw6q 3090 14 MAP MAP NNP cord-006870-f5w6fw6q 3090 15 . . . cord-006870-f5w6fw6q 3091 1 Impaired impaired JJ cord-006870-f5w6fw6q 3091 2 cerebral cerebral JJ cord-006870-f5w6fw6q 3091 3 autoregulation autoregulation NN cord-006870-f5w6fw6q 3091 4 has have VBZ cord-006870-f5w6fw6q 3091 5 been be VBN cord-006870-f5w6fw6q 3091 6 pre pre VBN cord-006870-f5w6fw6q 3091 7 Standard standard JJ cord-006870-f5w6fw6q 3091 8 maximal maximal JJ cord-006870-f5w6fw6q 3091 9 medical medical JJ cord-006870-f5w6fw6q 3091 10 therapy therapy NN cord-006870-f5w6fw6q 3091 11 was be VBD cord-006870-f5w6fw6q 3091 12 implemented implement VBN cord-006870-f5w6fw6q 3091 13 to to TO cord-006870-f5w6fw6q 3091 14 treat treat VB cord-006870-f5w6fw6q 3091 15 elevated elevated JJ cord-006870-f5w6fw6q 3091 16 ICP ICP NNP cord-006870-f5w6fw6q 3091 17 , , , cord-006870-f5w6fw6q 3091 18 cerebral cerebral JJ cord-006870-f5w6fw6q 3091 19 edema edema NN cord-006870-f5w6fw6q 3091 20 , , , cord-006870-f5w6fw6q 3091 21 etc etc FW cord-006870-f5w6fw6q 3091 22 . . . cord-006870-f5w6fw6q 3092 1 Patients patient NNS cord-006870-f5w6fw6q 3092 2 with with IN cord-006870-f5w6fw6q 3092 3 withdrawal withdrawal NN cord-006870-f5w6fw6q 3092 4 of of IN cord-006870-f5w6fw6q 3092 5 care care NN cord-006870-f5w6fw6q 3092 6 in in IN cord-006870-f5w6fw6q 3092 7 the the DT cord-006870-f5w6fw6q 3092 8 first first JJ cord-006870-f5w6fw6q 3092 9 48 48 CD cord-006870-f5w6fw6q 3092 10 hours hour NNS cord-006870-f5w6fw6q 3092 11 or or CC cord-006870-f5w6fw6q 3092 12 brain brain NN cord-006870-f5w6fw6q 3092 13 death death NN cord-006870-f5w6fw6q 3092 14 on on IN cord-006870-f5w6fw6q 3092 15 neurological neurological JJ cord-006870-f5w6fw6q 3092 16 exam exam NN cord-006870-f5w6fw6q 3092 17 were be VBD cord-006870-f5w6fw6q 3092 18 excluded exclude VBN cord-006870-f5w6fw6q 3092 19 . . . cord-006870-f5w6fw6q 3093 1 Thirty thirty CD cord-006870-f5w6fw6q 3093 2 comatose comatose JJ cord-006870-f5w6fw6q 3093 3 patients patient NNS cord-006870-f5w6fw6q 3093 4 from from IN cord-006870-f5w6fw6q 3093 5 acute acute JJ cord-006870-f5w6fw6q 3093 6 brain brain NN cord-006870-f5w6fw6q 3093 7 injuries injury NNS cord-006870-f5w6fw6q 3093 8 ( ( -LRB- cord-006870-f5w6fw6q 3093 9 16 16 CD cord-006870-f5w6fw6q 3093 10 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3093 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3093 12 , , , cord-006870-f5w6fw6q 3093 13 6 6 CD cord-006870-f5w6fw6q 3093 14 TBI TBI NNP cord-006870-f5w6fw6q 3093 15 , , , cord-006870-f5w6fw6q 3093 16 5 5 CD cord-006870-f5w6fw6q 3093 17 aneurysmal aneurysmal NN cord-006870-f5w6fw6q 3093 18 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3093 19 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3093 20 , , , cord-006870-f5w6fw6q 3093 21 2 2 CD cord-006870-f5w6fw6q 3093 22 intraventricular intraventricular JJ cord-006870-f5w6fw6q 3093 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3093 24 , , , cord-006870-f5w6fw6q 3093 25 1 1 CD cord-006870-f5w6fw6q 3093 26 hypoxic hypoxic JJ cord-006870-f5w6fw6q 3093 27 ischemic ischemic JJ cord-006870-f5w6fw6q 3093 28 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 3093 29 ) ) -RRB- cord-006870-f5w6fw6q 3093 30 were be VBD cord-006870-f5w6fw6q 3093 31 studied study VBN cord-006870-f5w6fw6q 3093 32 . . . cord-006870-f5w6fw6q 3094 1 The the DT cord-006870-f5w6fw6q 3094 2 average average JJ cord-006870-f5w6fw6q 3094 3 PRx PRx NNS cord-006870-f5w6fw6q 3094 4 upon upon IN cord-006870-f5w6fw6q 3094 5 starting start VBG cord-006870-f5w6fw6q 3094 6 neuromonitoring neuromonitore VBG cord-006870-f5w6fw6q 3094 7 using use VBG cord-006870-f5w6fw6q 3094 8 PRx PRx NNS cord-006870-f5w6fw6q 3094 9 was be VBD cord-006870-f5w6fw6q 3094 10 0.3 0.3 CD cord-006870-f5w6fw6q 3094 11 ± ± CD cord-006870-f5w6fw6q 3094 12 0.35 0.35 CD cord-006870-f5w6fw6q 3094 13 ( ( -LRB- cord-006870-f5w6fw6q 3094 14 impaired impaired JJ cord-006870-f5w6fw6q 3094 15 ) ) -RRB- cord-006870-f5w6fw6q 3094 16 , , , cord-006870-f5w6fw6q 3094 17 whereas whereas IN cord-006870-f5w6fw6q 3094 18 the the DT cord-006870-f5w6fw6q 3094 19 average average JJ cord-006870-f5w6fw6q 3094 20 PRx PRx NNS cord-006870-f5w6fw6q 3094 21 at at IN cord-006870-f5w6fw6q 3094 22 the the DT cord-006870-f5w6fw6q 3094 23 end end NN cord-006870-f5w6fw6q 3094 24 of of IN cord-006870-f5w6fw6q 3094 25 day day NN cord-006870-f5w6fw6q 3094 26 3 3 CD cord-006870-f5w6fw6q 3094 27 of of IN cord-006870-f5w6fw6q 3094 28 neuromonitoring neuromonitore VBG cord-006870-f5w6fw6q 3094 29 was be VBD cord-006870-f5w6fw6q 3094 30 0 0 CD cord-006870-f5w6fw6q 3094 31 ± ± CD cord-006870-f5w6fw6q 3094 32 0.10 0.10 CD cord-006870-f5w6fw6q 3094 33 ( ( -LRB- cord-006870-f5w6fw6q 3094 34 restored restore VBN cord-006870-f5w6fw6q 3094 35 ) ) -RRB- cord-006870-f5w6fw6q 3094 36 . . . cord-006870-f5w6fw6q 3095 1 One one CD cord-006870-f5w6fw6q 3095 2 third third NN cord-006870-f5w6fw6q 3095 3 of of IN cord-006870-f5w6fw6q 3095 4 the the DT cord-006870-f5w6fw6q 3095 5 patients patient NNS cord-006870-f5w6fw6q 3095 6 had have VBD cord-006870-f5w6fw6q 3095 7 ICP ICP NNP cord-006870-f5w6fw6q 3095 8 crisis crisis NN cord-006870-f5w6fw6q 3095 9 during during IN cord-006870-f5w6fw6q 3095 10 monitoring monitoring NN cord-006870-f5w6fw6q 3095 11 . . . cord-006870-f5w6fw6q 3096 1 The the DT cord-006870-f5w6fw6q 3096 2 average average JJ cord-006870-f5w6fw6q 3096 3 opening open VBG cord-006870-f5w6fw6q 3096 4 ICP=8.3 icp=8.3 NN cord-006870-f5w6fw6q 3096 5 , , , cord-006870-f5w6fw6q 3096 6 average average JJ cord-006870-f5w6fw6q 3096 7 highest highest RBS cord-006870-f5w6fw6q 3096 8 recorded record VBN cord-006870-f5w6fw6q 3096 9 ICP=26.9 icp=26.9 ADD cord-006870-f5w6fw6q 3096 10 . . . cord-006870-f5w6fw6q 3097 1 Impaired impaired JJ cord-006870-f5w6fw6q 3097 2 cerebral cerebral JJ cord-006870-f5w6fw6q 3097 3 autoregulation autoregulation NN cord-006870-f5w6fw6q 3097 4 has have VBZ cord-006870-f5w6fw6q 3097 5 been be VBN cord-006870-f5w6fw6q 3097 6 implicated implicate VBN cord-006870-f5w6fw6q 3097 7 as as IN cord-006870-f5w6fw6q 3097 8 a a DT cord-006870-f5w6fw6q 3097 9 predictor predictor NN cord-006870-f5w6fw6q 3097 10 of of IN cord-006870-f5w6fw6q 3097 11 clinical clinical JJ cord-006870-f5w6fw6q 3097 12 outcome outcome NN cord-006870-f5w6fw6q 3097 13 . . . cord-006870-f5w6fw6q 3098 1 Aggressive aggressive JJ cord-006870-f5w6fw6q 3098 2 medical medical JJ cord-006870-f5w6fw6q 3098 3 therapy therapy NN cord-006870-f5w6fw6q 3098 4 instituted institute VBN cord-006870-f5w6fw6q 3098 5 by by IN cord-006870-f5w6fw6q 3098 6 the the DT cord-006870-f5w6fw6q 3098 7 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3098 8 care care NN cord-006870-f5w6fw6q 3098 9 team team NN cord-006870-f5w6fw6q 3098 10 ( ( -LRB- cord-006870-f5w6fw6q 3098 11 ICP ICP NNP cord-006870-f5w6fw6q 3098 12 and and CC cord-006870-f5w6fw6q 3098 13 cerebral cerebral JJ cord-006870-f5w6fw6q 3098 14 edema edema NN cord-006870-f5w6fw6q 3098 15 management management NN cord-006870-f5w6fw6q 3098 16 , , , cord-006870-f5w6fw6q 3098 17 blood blood NN cord-006870-f5w6fw6q 3098 18 pressure pressure NN cord-006870-f5w6fw6q 3098 19 control control NN cord-006870-f5w6fw6q 3098 20 , , , cord-006870-f5w6fw6q 3098 21 etc etc FW cord-006870-f5w6fw6q 3098 22 . . . cord-006870-f5w6fw6q 3098 23 ) ) -RRB- cord-006870-f5w6fw6q 3098 24 may may MD cord-006870-f5w6fw6q 3098 25 result result VB cord-006870-f5w6fw6q 3098 26 in in IN cord-006870-f5w6fw6q 3098 27 restoration restoration NN cord-006870-f5w6fw6q 3098 28 of of IN cord-006870-f5w6fw6q 3098 29 cerebral cerebral JJ cord-006870-f5w6fw6q 3098 30 vasomotor vasomotor NN cord-006870-f5w6fw6q 3098 31 reactivity reactivity NN cord-006870-f5w6fw6q 3098 32 measured measure VBN cord-006870-f5w6fw6q 3098 33 by by IN cord-006870-f5w6fw6q 3098 34 PRx PRx NNS cord-006870-f5w6fw6q 3098 35 by by IN cord-006870-f5w6fw6q 3098 36 intensive intensive JJ cord-006870-f5w6fw6q 3098 37 care care NN cord-006870-f5w6fw6q 3098 38 day day NN cord-006870-f5w6fw6q 3098 39 3 3 CD cord-006870-f5w6fw6q 3098 40 - - SYM cord-006870-f5w6fw6q 3098 41 5 5 CD cord-006870-f5w6fw6q 3098 42 . . . cord-006870-f5w6fw6q 3099 1 Restoration restoration NN cord-006870-f5w6fw6q 3099 2 of of IN cord-006870-f5w6fw6q 3099 3 cerebral cerebral JJ cord-006870-f5w6fw6q 3099 4 vascular vascular JJ cord-006870-f5w6fw6q 3099 5 reactivity reactivity NN cord-006870-f5w6fw6q 3099 6 may may MD cord-006870-f5w6fw6q 3099 7 be be VB cord-006870-f5w6fw6q 3099 8 a a DT cord-006870-f5w6fw6q 3099 9 necessary necessary JJ cord-006870-f5w6fw6q 3099 10 but but CC cord-006870-f5w6fw6q 3099 11 not not RB cord-006870-f5w6fw6q 3099 12 sufficient sufficient JJ cord-006870-f5w6fw6q 3099 13 for for IN cord-006870-f5w6fw6q 3099 14 favorable favorable JJ cord-006870-f5w6fw6q 3099 15 outcome outcome NN cord-006870-f5w6fw6q 3099 16 . . . cord-006870-f5w6fw6q 3100 1 Elevated elevated JJ cord-006870-f5w6fw6q 3100 2 intracranial intracranial JJ cord-006870-f5w6fw6q 3100 3 pressure pressure NN cord-006870-f5w6fw6q 3100 4 ( ( -LRB- cord-006870-f5w6fw6q 3100 5 ICP ICP NNP cord-006870-f5w6fw6q 3100 6 ) ) -RRB- cord-006870-f5w6fw6q 3100 7 is be VBZ cord-006870-f5w6fw6q 3100 8 an an DT cord-006870-f5w6fw6q 3100 9 important important JJ cord-006870-f5w6fw6q 3100 10 cause cause NN cord-006870-f5w6fw6q 3100 11 of of IN cord-006870-f5w6fw6q 3100 12 death death NN cord-006870-f5w6fw6q 3100 13 following follow VBG cord-006870-f5w6fw6q 3100 14 acute acute JJ cord-006870-f5w6fw6q 3100 15 liver liver NN cord-006870-f5w6fw6q 3100 16 failure failure NN cord-006870-f5w6fw6q 3100 17 ( ( -LRB- cord-006870-f5w6fw6q 3100 18 ALF ALF NNP cord-006870-f5w6fw6q 3100 19 ) ) -RRB- cord-006870-f5w6fw6q 3100 20 . . . cord-006870-f5w6fw6q 3101 1 While while IN cord-006870-f5w6fw6q 3101 2 invasive invasive JJ cord-006870-f5w6fw6q 3101 3 ICP ICP NNP cord-006870-f5w6fw6q 3101 4 monitoring monitoring NN cord-006870-f5w6fw6q 3101 5 ( ( -LRB- cord-006870-f5w6fw6q 3101 6 IICPM IICPM NNP cord-006870-f5w6fw6q 3101 7 ) ) -RRB- cord-006870-f5w6fw6q 3101 8 remains remain VBZ cord-006870-f5w6fw6q 3101 9 the the DT cord-006870-f5w6fw6q 3101 10 gold gold NN cord-006870-f5w6fw6q 3101 11 standard standard NN cord-006870-f5w6fw6q 3101 12 , , , cord-006870-f5w6fw6q 3101 13 the the DT cord-006870-f5w6fw6q 3101 14 presence presence NN cord-006870-f5w6fw6q 3101 15 of of IN cord-006870-f5w6fw6q 3101 16 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 3101 17 increases increase VBZ cord-006870-f5w6fw6q 3101 18 the the DT cord-006870-f5w6fw6q 3101 19 risk risk NN cord-006870-f5w6fw6q 3101 20 of of IN cord-006870-f5w6fw6q 3101 21 bleeding bleed VBG cord-006870-f5w6fw6q 3101 22 in in IN cord-006870-f5w6fw6q 3101 23 ALF ALF NNP cord-006870-f5w6fw6q 3101 24 . . . cord-006870-f5w6fw6q 3102 1 Measurement measurement NN cord-006870-f5w6fw6q 3102 2 of of IN cord-006870-f5w6fw6q 3102 3 optic optic JJ cord-006870-f5w6fw6q 3102 4 nerve nerve NN cord-006870-f5w6fw6q 3102 5 sheath sheath NN cord-006870-f5w6fw6q 3102 6 diameter diameter NN cord-006870-f5w6fw6q 3102 7 ( ( -LRB- cord-006870-f5w6fw6q 3102 8 ONSD ONSD NNP cord-006870-f5w6fw6q 3102 9 ) ) -RRB- cord-006870-f5w6fw6q 3102 10 using use VBG cord-006870-f5w6fw6q 3102 11 Optic Optic NNP cord-006870-f5w6fw6q 3102 12 Nerve nerve NN cord-006870-f5w6fw6q 3102 13 Ultrasound Ultrasound NNP cord-006870-f5w6fw6q 3102 14 ( ( -LRB- cord-006870-f5w6fw6q 3102 15 ONUS onus NN cord-006870-f5w6fw6q 3102 16 ) ) -RRB- cord-006870-f5w6fw6q 3102 17 may may MD cord-006870-f5w6fw6q 3102 18 accurately accurately RB cord-006870-f5w6fw6q 3102 19 detect detect VB cord-006870-f5w6fw6q 3102 20 elevated elevate VBN cord-006870-f5w6fw6q 3102 21 ICP ICP NNP cord-006870-f5w6fw6q 3102 22 . . . cord-006870-f5w6fw6q 3103 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3103 2 goal goal NN cord-006870-f5w6fw6q 3103 3 was be VBD cord-006870-f5w6fw6q 3103 4 to to TO cord-006870-f5w6fw6q 3103 5 study study VB cord-006870-f5w6fw6q 3103 6 the the DT cord-006870-f5w6fw6q 3103 7 ability ability NN cord-006870-f5w6fw6q 3103 8 of of IN cord-006870-f5w6fw6q 3103 9 ONUS onus NN cord-006870-f5w6fw6q 3103 10 to to TO cord-006870-f5w6fw6q 3103 11 detect detect VB cord-006870-f5w6fw6q 3103 12 sustained sustained JJ cord-006870-f5w6fw6q 3103 13 intracranial intracranial JJ cord-006870-f5w6fw6q 3103 14 hypertension hypertension NN cord-006870-f5w6fw6q 3103 15 following follow VBG cord-006870-f5w6fw6q 3103 16 ALF ALF NNP cord-006870-f5w6fw6q 3103 17 , , , cord-006870-f5w6fw6q 3103 18 and and CC cord-006870-f5w6fw6q 3103 19 to to TO cord-006870-f5w6fw6q 3103 20 predict predict VB cord-006870-f5w6fw6q 3103 21 death death NN cord-006870-f5w6fw6q 3103 22 and and CC cord-006870-f5w6fw6q 3103 23 Therapeutic therapeutic JJ cord-006870-f5w6fw6q 3103 24 Intensity intensity NN cord-006870-f5w6fw6q 3103 25 Level level NN cord-006870-f5w6fw6q 3103 26 ( ( -LRB- cord-006870-f5w6fw6q 3103 27 TIL TIL NNP cord-006870-f5w6fw6q 3103 28 ) ) -RRB- cord-006870-f5w6fw6q 3103 29 , , , cord-006870-f5w6fw6q 3103 30 a a DT cord-006870-f5w6fw6q 3103 31 quantitative quantitative JJ cord-006870-f5w6fw6q 3103 32 measure measure NN cord-006870-f5w6fw6q 3103 33 of of IN cord-006870-f5w6fw6q 3103 34 the the DT cord-006870-f5w6fw6q 3103 35 intensity intensity NN cord-006870-f5w6fw6q 3103 36 of of IN cord-006870-f5w6fw6q 3103 37 treatment treatment NN cord-006870-f5w6fw6q 3103 38 required require VBN cord-006870-f5w6fw6q 3103 39 to to TO cord-006870-f5w6fw6q 3103 40 control control VB cord-006870-f5w6fw6q 3103 41 ICP ICP NNP cord-006870-f5w6fw6q 3103 42 . . . cord-006870-f5w6fw6q 3104 1 Consecutive consecutive JJ cord-006870-f5w6fw6q 3104 2 patients patient NNS cord-006870-f5w6fw6q 3104 3 with with IN cord-006870-f5w6fw6q 3104 4 ALF ALF NNP cord-006870-f5w6fw6q 3104 5 admitted admit VBD cord-006870-f5w6fw6q 3104 6 to to IN cord-006870-f5w6fw6q 3104 7 our -PRON- PRP$ cord-006870-f5w6fw6q 3104 8 institution institution NN cord-006870-f5w6fw6q 3104 9 in in IN cord-006870-f5w6fw6q 3104 10 a a DT cord-006870-f5w6fw6q 3104 11 6-year 6-year JJ cord-006870-f5w6fw6q 3104 12 period period NN cord-006870-f5w6fw6q 3104 13 underwent undergo VBD cord-006870-f5w6fw6q 3104 14 ONUS onus NN cord-006870-f5w6fw6q 3104 15 . . . cord-006870-f5w6fw6q 3105 1 Blinded blinded JJ cord-006870-f5w6fw6q 3105 2 measurement measurement NN cord-006870-f5w6fw6q 3105 3 of of IN cord-006870-f5w6fw6q 3105 4 ONSD ONSD NNP cord-006870-f5w6fw6q 3105 5 was be VBD cord-006870-f5w6fw6q 3105 6 performed perform VBN cord-006870-f5w6fw6q 3105 7 from from IN cord-006870-f5w6fw6q 3105 8 deidentified deidentifie VBN cord-006870-f5w6fw6q 3105 9 ONUS onus NN cord-006870-f5w6fw6q 3105 10 videos video NNS cord-006870-f5w6fw6q 3105 11 . . . cord-006870-f5w6fw6q 3106 1 Patients patient NNS cord-006870-f5w6fw6q 3106 2 underwent undergo VBD cord-006870-f5w6fw6q 3106 3 IICPM IICPM NNP cord-006870-f5w6fw6q 3106 4 on on IN cord-006870-f5w6fw6q 3106 5 the the DT cord-006870-f5w6fw6q 3106 6 basis basis NN cord-006870-f5w6fw6q 3106 7 of of IN cord-006870-f5w6fw6q 3106 8 an an DT cord-006870-f5w6fw6q 3106 9 institutional institutional JJ cord-006870-f5w6fw6q 3106 10 protocol protocol NN cord-006870-f5w6fw6q 3106 11 for for IN cord-006870-f5w6fw6q 3106 12 selection selection NN cord-006870-f5w6fw6q 3106 13 of of IN cord-006870-f5w6fw6q 3106 14 appropriate appropriate JJ cord-006870-f5w6fw6q 3106 15 candidates candidate NNS cord-006870-f5w6fw6q 3106 16 , , , cord-006870-f5w6fw6q 3106 17 coagulopathy coagulopathy NN cord-006870-f5w6fw6q 3106 18 reversal reversal NN cord-006870-f5w6fw6q 3106 19 and and CC cord-006870-f5w6fw6q 3106 20 insertion insertion NN cord-006870-f5w6fw6q 3106 21 of of IN cord-006870-f5w6fw6q 3106 22 an an DT cord-006870-f5w6fw6q 3106 23 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 3106 24 monitor monitor NN cord-006870-f5w6fw6q 3106 25 . . . cord-006870-f5w6fw6q 3107 1 The the DT cord-006870-f5w6fw6q 3107 2 TIL TIL NNP cord-006870-f5w6fw6q 3107 3 - - HYPH cord-006870-f5w6fw6q 3107 4 basic basic NN cord-006870-f5w6fw6q 3107 5 for for IN cord-006870-f5w6fw6q 3107 6 management management NN cord-006870-f5w6fw6q 3107 7 of of IN cord-006870-f5w6fw6q 3107 8 ICP ICP NNP cord-006870-f5w6fw6q 3107 9 during during IN cord-006870-f5w6fw6q 3107 10 the the DT cord-006870-f5w6fw6q 3107 11 ICU ICU NNP cord-006870-f5w6fw6q 3107 12 stay stay NN cord-006870-f5w6fw6q 3107 13 was be VBD cord-006870-f5w6fw6q 3107 14 recorded record VBN cord-006870-f5w6fw6q 3107 15 . . . cord-006870-f5w6fw6q 3108 1 The the DT cord-006870-f5w6fw6q 3108 2 ability ability NN cord-006870-f5w6fw6q 3108 3 of of IN cord-006870-f5w6fw6q 3108 4 highest high JJS cord-006870-f5w6fw6q 3108 5 ONSD ONSD NNP cord-006870-f5w6fw6q 3108 6 to to TO cord-006870-f5w6fw6q 3108 7 predict predict VB cord-006870-f5w6fw6q 3108 8 concurrent concurrent JJ cord-006870-f5w6fw6q 3108 9 ICP>20mmHg icp>20mmhg RB cord-006870-f5w6fw6q 3108 10 at at IN cord-006870-f5w6fw6q 3108 11 the the DT cord-006870-f5w6fw6q 3108 12 time time NN cord-006870-f5w6fw6q 3108 13 of of IN cord-006870-f5w6fw6q 3108 14 measurement measurement NN cord-006870-f5w6fw6q 3108 15 , , , cord-006870-f5w6fw6q 3108 16 sustained sustain VBD cord-006870-f5w6fw6q 3108 17 ICP ICP NNP cord-006870-f5w6fw6q 3108 18 elevation elevation NN cord-006870-f5w6fw6q 3108 19 > > XX cord-006870-f5w6fw6q 3109 1 20mmHg 20mmhg CD cord-006870-f5w6fw6q 3110 1 at at IN cord-006870-f5w6fw6q 3110 2 any any DT cord-006870-f5w6fw6q 3110 3 time time NN cord-006870-f5w6fw6q 3110 4 and and CC cord-006870-f5w6fw6q 3110 5 TIL TIL NNP cord-006870-f5w6fw6q 3110 6 - - HYPH cord-006870-f5w6fw6q 3110 7 basic>2 basic>2 NNP cord-006870-f5w6fw6q 3110 8 was be VBD cord-006870-f5w6fw6q 3110 9 assessed assess VBN cord-006870-f5w6fw6q 3110 10 in in IN cord-006870-f5w6fw6q 3110 11 patients patient NNS cord-006870-f5w6fw6q 3110 12 who who WP cord-006870-f5w6fw6q 3110 13 underwent undergo VBD cord-006870-f5w6fw6q 3110 14 IICPM IICPM NNP cord-006870-f5w6fw6q 3110 15 , , , cord-006870-f5w6fw6q 3110 16 while while IN cord-006870-f5w6fw6q 3110 17 prediction prediction NN cord-006870-f5w6fw6q 3110 18 of of IN cord-006870-f5w6fw6q 3110 19 death death NN cord-006870-f5w6fw6q 3110 20 was be VBD cord-006870-f5w6fw6q 3110 21 assessed assess VBN cord-006870-f5w6fw6q 3110 22 in in IN cord-006870-f5w6fw6q 3110 23 all all DT cord-006870-f5w6fw6q 3110 24 patients patient NNS cord-006870-f5w6fw6q 3110 25 . . . cord-006870-f5w6fw6q 3111 1 Receiver receiver NN cord-006870-f5w6fw6q 3111 2 Operating operating NN cord-006870-f5w6fw6q 3111 3 Characteristic characteristic NN cord-006870-f5w6fw6q 3111 4 ( ( -LRB- cord-006870-f5w6fw6q 3111 5 ROC ROC NNP cord-006870-f5w6fw6q 3111 6 ) ) -RRB- cord-006870-f5w6fw6q 3111 7 curves curve NNS cord-006870-f5w6fw6q 3111 8 were be VBD cord-006870-f5w6fw6q 3111 9 constructed construct VBN cord-006870-f5w6fw6q 3111 10 for for IN cord-006870-f5w6fw6q 3111 11 the the DT cord-006870-f5w6fw6q 3111 12 outcomes outcome NNS cord-006870-f5w6fw6q 3111 13 of of IN cord-006870-f5w6fw6q 3111 14 interest interest NN cord-006870-f5w6fw6q 3111 15 . . . cord-006870-f5w6fw6q 3112 1 Thirty thirty CD cord-006870-f5w6fw6q 3112 2 - - HYPH cord-006870-f5w6fw6q 3112 3 nine nine CD cord-006870-f5w6fw6q 3112 4 patients patient NNS cord-006870-f5w6fw6q 3112 5 with with IN cord-006870-f5w6fw6q 3112 6 ALF ALF NNP cord-006870-f5w6fw6q 3112 7 were be VBD cord-006870-f5w6fw6q 3112 8 admitted admit VBN cord-006870-f5w6fw6q 3112 9 during during IN cord-006870-f5w6fw6q 3112 10 the the DT cord-006870-f5w6fw6q 3112 11 study study NN cord-006870-f5w6fw6q 3112 12 period period NN cord-006870-f5w6fw6q 3112 13 , , , cord-006870-f5w6fw6q 3112 14 29/39(74 29/39(74 CD cord-006870-f5w6fw6q 3112 15 % % NN cord-006870-f5w6fw6q 3112 16 ) ) -RRB- cord-006870-f5w6fw6q 3113 1 underwent undergo VBD cord-006870-f5w6fw6q 3113 2 ONUS onus NN cord-006870-f5w6fw6q 3113 3 , , , cord-006870-f5w6fw6q 3113 4 25/39(64 25/39(64 CD cord-006870-f5w6fw6q 3113 5 % % NN cord-006870-f5w6fw6q 3113 6 ) ) -RRB- cord-006870-f5w6fw6q 3113 7 underwent undergo VBD cord-006870-f5w6fw6q 3113 8 IICPM IICPM NNP cord-006870-f5w6fw6q 3113 9 and and CC cord-006870-f5w6fw6q 3113 10 19(49 19(49 CD cord-006870-f5w6fw6q 3113 11 % % NN cord-006870-f5w6fw6q 3113 12 ) ) -RRB- cord-006870-f5w6fw6q 3113 13 died die VBD cord-006870-f5w6fw6q 3113 14 . . . cord-006870-f5w6fw6q 3114 1 Of of IN cord-006870-f5w6fw6q 3114 2 25 25 CD cord-006870-f5w6fw6q 3114 3 patients patient NNS cord-006870-f5w6fw6q 3114 4 who who WP cord-006870-f5w6fw6q 3114 5 underwent undergo VBD cord-006870-f5w6fw6q 3114 6 IICPM IICPM NNP cord-006870-f5w6fw6q 3114 7 , , , cord-006870-f5w6fw6q 3114 8 13(52 13(52 CD cord-006870-f5w6fw6q 3114 9 % % NN cord-006870-f5w6fw6q 3114 10 ) ) -RRB- cord-006870-f5w6fw6q 3114 11 developed develop VBD cord-006870-f5w6fw6q 3114 12 sustained sustain VBN cord-006870-f5w6fw6q 3114 13 ICP ICP NNP cord-006870-f5w6fw6q 3114 14 elevation elevation NN cord-006870-f5w6fw6q 3114 15 and and CC cord-006870-f5w6fw6q 3114 16 7(28 7(28 CD cord-006870-f5w6fw6q 3114 17 % % NN cord-006870-f5w6fw6q 3114 18 ) ) -RRB- cord-006870-f5w6fw6q 3114 19 had have VBD cord-006870-f5w6fw6q 3114 20 a a DT cord-006870-f5w6fw6q 3114 21 TIL TIL NNP cord-006870-f5w6fw6q 3114 22 - - HYPH cord-006870-f5w6fw6q 3114 23 basic>2 basic>2 NN cord-006870-f5w6fw6q 3114 24 . . . cord-006870-f5w6fw6q 3115 1 The the DT cord-006870-f5w6fw6q 3115 2 ROC ROC NNP cord-006870-f5w6fw6q 3115 3 Area Area NNP cord-006870-f5w6fw6q 3115 4 Under under IN cord-006870-f5w6fw6q 3115 5 the the DT cord-006870-f5w6fw6q 3115 6 Curve curve NN cord-006870-f5w6fw6q 3115 7 ( ( -LRB- cord-006870-f5w6fw6q 3115 8 AUC AUC NNP cord-006870-f5w6fw6q 3115 9 ) ) -RRB- cord-006870-f5w6fw6q 3115 10 of of IN cord-006870-f5w6fw6q 3115 11 ONSD ONSD NNP cord-006870-f5w6fw6q 3115 12 for for IN cord-006870-f5w6fw6q 3115 13 prediction prediction NN cord-006870-f5w6fw6q 3115 14 of of IN cord-006870-f5w6fw6q 3115 15 concurrent concurrent JJ cord-006870-f5w6fw6q 3115 16 ICP>20mmHg ICP>20mmHg NNP cord-006870-f5w6fw6q 3115 17 was be VBD cord-006870-f5w6fw6q 3115 18 0.63(95 0.63(95 CD cord-006870-f5w6fw6q 3115 19 % % NN cord-006870-f5w6fw6q 3115 20 Confidence confidence NN cord-006870-f5w6fw6q 3115 21 - - : cord-006870-f5w6fw6q 3115 22 Interval interval NN cord-006870-f5w6fw6q 3115 23 0.39 0.39 CD cord-006870-f5w6fw6q 3115 24 - - SYM cord-006870-f5w6fw6q 3115 25 0.82 0.82 CD cord-006870-f5w6fw6q 3115 26 , , , cord-006870-f5w6fw6q 3115 27 p=0.42 p=0.42 NNP cord-006870-f5w6fw6q 3115 28 for for IN cord-006870-f5w6fw6q 3115 29 null null JJ cord-006870-f5w6fw6q 3115 30 hypothesis hypothesis NN cord-006870-f5w6fw6q 3115 31 of of IN cord-006870-f5w6fw6q 3115 32 AUC=0.5 AUC=0.5 NNP cord-006870-f5w6fw6q 3115 33 ) ) -RRB- cord-006870-f5w6fw6q 3115 34 , , , cord-006870-f5w6fw6q 3115 35 sustained sustain VBD cord-006870-f5w6fw6q 3115 36 ICP ICP NNP cord-006870-f5w6fw6q 3115 37 elevation elevation NN cord-006870-f5w6fw6q 3115 38 at at IN cord-006870-f5w6fw6q 3115 39 any any DT cord-006870-f5w6fw6q 3115 40 time time NN cord-006870-f5w6fw6q 3115 41 was be VBD cord-006870-f5w6fw6q 3115 42 0.51(0.28 0.51(0.28 CD cord-006870-f5w6fw6q 3115 43 - - HYPH cord-006870-f5w6fw6q 3115 44 0.73,p=0.97 0.73,p=0.97 NNP cord-006870-f5w6fw6q 3115 45 ) ) -RRB- cord-006870-f5w6fw6q 3115 46 , , , cord-006870-f5w6fw6q 3115 47 death death NN cord-006870-f5w6fw6q 3115 48 was be VBD cord-006870-f5w6fw6q 3115 49 0.56(0.36 0.56(0.36 CD cord-006870-f5w6fw6q 3115 50 - - HYPH cord-006870-f5w6fw6q 3115 51 0.74,p=0.59 0.74,p=0.59 CD cord-006870-f5w6fw6q 3115 52 ) ) -RRB- cord-006870-f5w6fw6q 3115 53 and and CC cord-006870-f5w6fw6q 3115 54 TIL>2 til>2 DT cord-006870-f5w6fw6q 3115 55 was be VBD cord-006870-f5w6fw6q 3115 56 0.61(0.42 0.61(0.42 CD cord-006870-f5w6fw6q 3115 57 - - HYPH cord-006870-f5w6fw6q 3115 58 0.79,p=0.33 0.79,p=0.33 CD cord-006870-f5w6fw6q 3115 59 ) ) -RRB- cord-006870-f5w6fw6q 3115 60 . . . cord-006870-f5w6fw6q 3116 1 In in IN cord-006870-f5w6fw6q 3116 2 patients patient NNS cord-006870-f5w6fw6q 3116 3 with with IN cord-006870-f5w6fw6q 3116 4 ALF ALF NNP cord-006870-f5w6fw6q 3116 5 , , , cord-006870-f5w6fw6q 3116 6 ONSD ONSD NNP cord-006870-f5w6fw6q 3116 7 measurement measurement NN cord-006870-f5w6fw6q 3116 8 performed perform VBD cord-006870-f5w6fw6q 3116 9 poorly poorly RB cord-006870-f5w6fw6q 3116 10 for for IN cord-006870-f5w6fw6q 3116 11 detection detection NN cord-006870-f5w6fw6q 3116 12 of of IN cord-006870-f5w6fw6q 3116 13 ICP ICP NNP cord-006870-f5w6fw6q 3116 14 elevation elevation NN cord-006870-f5w6fw6q 3116 15 , , , cord-006870-f5w6fw6q 3116 16 and and CC cord-006870-f5w6fw6q 3116 17 was be VBD cord-006870-f5w6fw6q 3116 18 a a DT cord-006870-f5w6fw6q 3116 19 poor poor JJ cord-006870-f5w6fw6q 3116 20 predictor predictor NN cord-006870-f5w6fw6q 3116 21 of of IN cord-006870-f5w6fw6q 3116 22 TIL TIL NNP cord-006870-f5w6fw6q 3116 23 and and CC cord-006870-f5w6fw6q 3116 24 death death NN cord-006870-f5w6fw6q 3116 25 . . . cord-006870-f5w6fw6q 3117 1 Limited limited JJ cord-006870-f5w6fw6q 3117 2 literature literature NN cord-006870-f5w6fw6q 3117 3 exists exist VBZ cord-006870-f5w6fw6q 3117 4 regarding regard VBG cord-006870-f5w6fw6q 3117 5 the the DT cord-006870-f5w6fw6q 3117 6 neurochemical neurochemical JJ cord-006870-f5w6fw6q 3117 7 and and CC cord-006870-f5w6fw6q 3117 8 physiologic physiologic JJ cord-006870-f5w6fw6q 3117 9 events event NNS cord-006870-f5w6fw6q 3117 10 that that WDT cord-006870-f5w6fw6q 3117 11 occur occur VBP cord-006870-f5w6fw6q 3117 12 as as IN cord-006870-f5w6fw6q 3117 13 brain brain NN cord-006870-f5w6fw6q 3117 14 death death NN cord-006870-f5w6fw6q 3117 15 develops develop VBZ cord-006870-f5w6fw6q 3117 16 . . . cord-006870-f5w6fw6q 3118 1 Using use VBG cord-006870-f5w6fw6q 3118 2 intracranial intracranial JJ cord-006870-f5w6fw6q 3118 3 multi multi JJ cord-006870-f5w6fw6q 3118 4 - - JJ cord-006870-f5w6fw6q 3118 5 modality modality JJ cord-006870-f5w6fw6q 3118 6 monitoring monitoring NN cord-006870-f5w6fw6q 3118 7 , , , cord-006870-f5w6fw6q 3118 8 we -PRON- PRP cord-006870-f5w6fw6q 3118 9 identify identify VBP cord-006870-f5w6fw6q 3118 10 physiological physiological JJ cord-006870-f5w6fw6q 3118 11 changes change NNS cord-006870-f5w6fw6q 3118 12 that that WDT cord-006870-f5w6fw6q 3118 13 signal signal VBP cord-006870-f5w6fw6q 3118 14 the the DT cord-006870-f5w6fw6q 3118 15 onset onset NN cord-006870-f5w6fw6q 3118 16 of of IN cord-006870-f5w6fw6q 3118 17 brain brain NN cord-006870-f5w6fw6q 3118 18 death death NN cord-006870-f5w6fw6q 3118 19 . . . cord-006870-f5w6fw6q 3119 1 We -PRON- PRP cord-006870-f5w6fw6q 3119 2 measured measure VBD cord-006870-f5w6fw6q 3119 3 intracranial intracranial JJ cord-006870-f5w6fw6q 3119 4 pressure pressure NN cord-006870-f5w6fw6q 3119 5 ( ( -LRB- cord-006870-f5w6fw6q 3119 6 ICP ICP NNP cord-006870-f5w6fw6q 3119 7 ) ) -RRB- cord-006870-f5w6fw6q 3119 8 , , , cord-006870-f5w6fw6q 3119 9 brain brain NN cord-006870-f5w6fw6q 3119 10 partial partial JJ cord-006870-f5w6fw6q 3119 11 oxygen oxygen NN cord-006870-f5w6fw6q 3119 12 tension tension NN cord-006870-f5w6fw6q 3119 13 ( ( -LRB- cord-006870-f5w6fw6q 3119 14 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3119 15 ) ) -RRB- cord-006870-f5w6fw6q 3119 16 , , , cord-006870-f5w6fw6q 3119 17 cerebral cerebral JJ cord-006870-f5w6fw6q 3119 18 blood blood NN cord-006870-f5w6fw6q 3119 19 flow flow NN cord-006870-f5w6fw6q 3119 20 ( ( -LRB- cord-006870-f5w6fw6q 3119 21 CBF CBF NNP cord-006870-f5w6fw6q 3119 22 ) ) -RRB- cord-006870-f5w6fw6q 3119 23 , , , cord-006870-f5w6fw6q 3119 24 and and CC cord-006870-f5w6fw6q 3119 25 biochemical biochemical JJ cord-006870-f5w6fw6q 3119 26 correlates correlate NNS cord-006870-f5w6fw6q 3119 27 of of IN cord-006870-f5w6fw6q 3119 28 cerebral cerebral JJ cord-006870-f5w6fw6q 3119 29 metabolism metabolism NN cord-006870-f5w6fw6q 3119 30 in in IN cord-006870-f5w6fw6q 3119 31 4 4 CD cord-006870-f5w6fw6q 3119 32 patients patient NNS cord-006870-f5w6fw6q 3119 33 with with IN cord-006870-f5w6fw6q 3119 34 diffuse diffuse JJ cord-006870-f5w6fw6q 3119 35 hypoxic hypoxic JJ cord-006870-f5w6fw6q 3119 36 ischemic ischemic JJ cord-006870-f5w6fw6q 3119 37 brain brain NN cord-006870-f5w6fw6q 3119 38 injury injury NN cord-006870-f5w6fw6q 3119 39 after after IN cord-006870-f5w6fw6q 3119 40 cardiac cardiac JJ cord-006870-f5w6fw6q 3119 41 arrest arrest NN cord-006870-f5w6fw6q 3119 42 during during IN cord-006870-f5w6fw6q 3119 43 the the DT cord-006870-f5w6fw6q 3119 44 development development NN cord-006870-f5w6fw6q 3119 45 of of IN cord-006870-f5w6fw6q 3119 46 brain brain NN cord-006870-f5w6fw6q 3119 47 death death NN cord-006870-f5w6fw6q 3119 48 . . . cord-006870-f5w6fw6q 3120 1 Monitoring monitoring NN cord-006870-f5w6fw6q 3120 2 probes probe NNS cord-006870-f5w6fw6q 3120 3 were be VBD cord-006870-f5w6fw6q 3120 4 inserted insert VBN cord-006870-f5w6fw6q 3120 5 into into IN cord-006870-f5w6fw6q 3120 6 cerebral cerebral JJ cord-006870-f5w6fw6q 3120 7 white white JJ cord-006870-f5w6fw6q 3120 8 matter matter NN cord-006870-f5w6fw6q 3120 9 through through IN cord-006870-f5w6fw6q 3120 10 a a DT cord-006870-f5w6fw6q 3120 11 burr burr NN cord-006870-f5w6fw6q 3120 12 hole hole NN cord-006870-f5w6fw6q 3120 13 using use VBG cord-006870-f5w6fw6q 3120 14 a a DT cord-006870-f5w6fw6q 3120 15 CT CT NNP cord-006870-f5w6fw6q 3120 16 compatible compatible JJ cord-006870-f5w6fw6q 3120 17 multi multi JJ cord-006870-f5w6fw6q 3120 18 - - JJ cord-006870-f5w6fw6q 3120 19 lumen lumen JJ cord-006870-f5w6fw6q 3120 20 bolt bolt NN cord-006870-f5w6fw6q 3120 21 . . . cord-006870-f5w6fw6q 3121 1 Brain brain NN cord-006870-f5w6fw6q 3121 2 tissue tissue NN cord-006870-f5w6fw6q 3121 3 energy energy NN cord-006870-f5w6fw6q 3121 4 - - HYPH cord-006870-f5w6fw6q 3121 5 related relate VBN cord-006870-f5w6fw6q 3121 6 metabolites metabolite NNS cord-006870-f5w6fw6q 3121 7 ( ( -LRB- cord-006870-f5w6fw6q 3121 8 Lactate lactate NN cord-006870-f5w6fw6q 3121 9 , , , cord-006870-f5w6fw6q 3121 10 Pyruvate Pyruvate NNP cord-006870-f5w6fw6q 3121 11 , , , cord-006870-f5w6fw6q 3121 12 Glutamate glutamate NN cord-006870-f5w6fw6q 3121 13 , , , cord-006870-f5w6fw6q 3121 14 Glucose glucose NN cord-006870-f5w6fw6q 3121 15 , , , cord-006870-f5w6fw6q 3121 16 Glycerol Glycerol NNP cord-006870-f5w6fw6q 3121 17 ) ) -RRB- cord-006870-f5w6fw6q 3121 18 were be VBD cord-006870-f5w6fw6q 3121 19 measured measure VBN cord-006870-f5w6fw6q 3121 20 using use VBG cord-006870-f5w6fw6q 3121 21 a a DT cord-006870-f5w6fw6q 3121 22 bedside bedside NN cord-006870-f5w6fw6q 3121 23 microdialysis microdialysis NN cord-006870-f5w6fw6q 3121 24 analyzer analyzer NN cord-006870-f5w6fw6q 3121 25 . . . cord-006870-f5w6fw6q 3122 1 PbtO2 pbto2 NN cord-006870-f5w6fw6q 3122 2 and and CC cord-006870-f5w6fw6q 3122 3 temperature temperature NN cord-006870-f5w6fw6q 3122 4 were be VBD cord-006870-f5w6fw6q 3122 5 measured measure VBN cord-006870-f5w6fw6q 3122 6 via via IN cord-006870-f5w6fw6q 3122 7 a a DT cord-006870-f5w6fw6q 3122 8 Licox Licox NNP cord-006870-f5w6fw6q 3122 9 catheter catheter NN cord-006870-f5w6fw6q 3122 10 . . . cord-006870-f5w6fw6q 3123 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 3123 2 perfusion perfusion NN cord-006870-f5w6fw6q 3123 3 was be VBD cord-006870-f5w6fw6q 3123 4 measured measure VBN cord-006870-f5w6fw6q 3123 5 with with IN cord-006870-f5w6fw6q 3123 6 a a DT cord-006870-f5w6fw6q 3123 7 Hemedex Hemedex NNP cord-006870-f5w6fw6q 3123 8 Bowman Bowman NNP cord-006870-f5w6fw6q 3123 9 Perfusion Perfusion NNP cord-006870-f5w6fw6q 3123 10 monitor monitor NN cord-006870-f5w6fw6q 3123 11 . . . cord-006870-f5w6fw6q 3124 1 Brain Brain NNP cord-006870-f5w6fw6q 3124 2 death death NN cord-006870-f5w6fw6q 3124 3 was be VBD cord-006870-f5w6fw6q 3124 4 confirmed confirm VBN cord-006870-f5w6fw6q 3124 5 in in IN cord-006870-f5w6fw6q 3124 6 accordance accordance NN cord-006870-f5w6fw6q 3124 7 with with IN cord-006870-f5w6fw6q 3124 8 institutional institutional JJ cord-006870-f5w6fw6q 3124 9 guidelines guideline NNS cord-006870-f5w6fw6q 3124 10 . . . cord-006870-f5w6fw6q 3125 1 A a DT cord-006870-f5w6fw6q 3125 2 characteristic characteristic JJ cord-006870-f5w6fw6q 3125 3 pattern pattern NN cord-006870-f5w6fw6q 3125 4 of of IN cord-006870-f5w6fw6q 3125 5 physiologic physiologic JJ cord-006870-f5w6fw6q 3125 6 and and CC cord-006870-f5w6fw6q 3125 7 neurochemical neurochemical JJ cord-006870-f5w6fw6q 3125 8 findings finding NNS cord-006870-f5w6fw6q 3125 9 emerged emerge VBD cord-006870-f5w6fw6q 3125 10 as as IN cord-006870-f5w6fw6q 3125 11 brain brain NN cord-006870-f5w6fw6q 3125 12 death death NN cord-006870-f5w6fw6q 3125 13 occurred occur VBD cord-006870-f5w6fw6q 3125 14 . . . cord-006870-f5w6fw6q 3126 1 Absolute absolute JJ cord-006870-f5w6fw6q 3126 2 loss loss NN cord-006870-f5w6fw6q 3126 3 of of IN cord-006870-f5w6fw6q 3126 4 cerebral cerebral JJ cord-006870-f5w6fw6q 3126 5 autoregulation autoregulation NN cord-006870-f5w6fw6q 3126 6 , , , cord-006870-f5w6fw6q 3126 7 with with IN cord-006870-f5w6fw6q 3126 8 a a DT cord-006870-f5w6fw6q 3126 9 near near JJ cord-006870-f5w6fw6q 3126 10 perfect perfect JJ cord-006870-f5w6fw6q 3126 11 correlation correlation NN cord-006870-f5w6fw6q 3126 12 between between IN cord-006870-f5w6fw6q 3126 13 ICP ICP NNP cord-006870-f5w6fw6q 3126 14 and and CC cord-006870-f5w6fw6q 3126 15 MAP MAP NNP cord-006870-f5w6fw6q 3126 16 was be VBD cord-006870-f5w6fw6q 3126 17 followed follow VBN cord-006870-f5w6fw6q 3126 18 by by IN cord-006870-f5w6fw6q 3126 19 equalization equalization NN cord-006870-f5w6fw6q 3126 20 of of IN cord-006870-f5w6fw6q 3126 21 MAP MAP NNP cord-006870-f5w6fw6q 3126 22 and and CC cord-006870-f5w6fw6q 3126 23 ICP ICP NNP cord-006870-f5w6fw6q 3126 24 resulting result VBG cord-006870-f5w6fw6q 3126 25 in in IN cord-006870-f5w6fw6q 3126 26 progressive progressive JJ cord-006870-f5w6fw6q 3126 27 drop drop NN cord-006870-f5w6fw6q 3126 28 in in IN cord-006870-f5w6fw6q 3126 29 CPP CPP NNP cord-006870-f5w6fw6q 3126 30 to to IN cord-006870-f5w6fw6q 3126 31 zero zero CD cord-006870-f5w6fw6q 3126 32 , , , cord-006870-f5w6fw6q 3126 33 followed follow VBN cord-006870-f5w6fw6q 3126 34 by by IN cord-006870-f5w6fw6q 3126 35 a a DT cord-006870-f5w6fw6q 3126 36 progressive progressive JJ cord-006870-f5w6fw6q 3126 37 decline decline NN cord-006870-f5w6fw6q 3126 38 in in IN cord-006870-f5w6fw6q 3126 39 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3126 40 that that WDT cord-006870-f5w6fw6q 3126 41 became become VBD cord-006870-f5w6fw6q 3126 42 unresponsive unresponsive JJ cord-006870-f5w6fw6q 3126 43 to to IN cord-006870-f5w6fw6q 3126 44 a a DT cord-006870-f5w6fw6q 3126 45 100 100 CD cord-006870-f5w6fw6q 3126 46 % % NN cord-006870-f5w6fw6q 3126 47 FiO2 FiO2 NNS cord-006870-f5w6fw6q 3126 48 challenge challenge NN cord-006870-f5w6fw6q 3126 49 . . . cord-006870-f5w6fw6q 3127 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 3127 2 perfusion perfusion NN cord-006870-f5w6fw6q 3127 3 decreased decrease VBD cord-006870-f5w6fw6q 3127 4 in in IN cord-006870-f5w6fw6q 3127 5 tandem tandem NN cord-006870-f5w6fw6q 3127 6 with with IN cord-006870-f5w6fw6q 3127 7 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3127 8 . . . cord-006870-f5w6fw6q 3128 1 Lactate lactate NN cord-006870-f5w6fw6q 3128 2 / / SYM cord-006870-f5w6fw6q 3128 3 Pyruvate Pyruvate NNP cord-006870-f5w6fw6q 3128 4 ratio ratio NN cord-006870-f5w6fw6q 3128 5 ( ( -LRB- cord-006870-f5w6fw6q 3128 6 LPR LPR NNP cord-006870-f5w6fw6q 3128 7 ) ) -RRB- cord-006870-f5w6fw6q 3128 8 , , , cord-006870-f5w6fw6q 3128 9 glutamate glutamate NN cord-006870-f5w6fw6q 3128 10 , , , cord-006870-f5w6fw6q 3128 11 and and CC cord-006870-f5w6fw6q 3128 12 glycerol glycerol NN cord-006870-f5w6fw6q 3128 13 all all DT cord-006870-f5w6fw6q 3128 14 increased increase VBN cord-006870-f5w6fw6q 3128 15 precipitously precipitously RB cord-006870-f5w6fw6q 3128 16 , , , cord-006870-f5w6fw6q 3128 17 with with IN cord-006870-f5w6fw6q 3128 18 LPR LPR NNP cord-006870-f5w6fw6q 3128 19 consistently consistently RB cord-006870-f5w6fw6q 3128 20 > > XX cord-006870-f5w6fw6q 3129 1 1000 1000 CD cord-006870-f5w6fw6q 3129 2 . . . cord-006870-f5w6fw6q 3130 1 Brain brain NN cord-006870-f5w6fw6q 3130 2 temperature temperature NN cord-006870-f5w6fw6q 3130 3 decreased decrease VBD cord-006870-f5w6fw6q 3130 4 despite despite IN cord-006870-f5w6fw6q 3130 5 maintenance maintenance NN cord-006870-f5w6fw6q 3130 6 of of IN cord-006870-f5w6fw6q 3130 7 a a DT cord-006870-f5w6fw6q 3130 8 normal normal JJ cord-006870-f5w6fw6q 3130 9 core core NN cord-006870-f5w6fw6q 3130 10 temperature temperature NN cord-006870-f5w6fw6q 3130 11 . . . cord-006870-f5w6fw6q 3131 1 Finally finally RB cord-006870-f5w6fw6q 3131 2 , , , cord-006870-f5w6fw6q 3131 3 intracranial intracranial JJ cord-006870-f5w6fw6q 3131 4 compliance compliance NN cord-006870-f5w6fw6q 3131 5 , , , cord-006870-f5w6fw6q 3131 6 while while IN cord-006870-f5w6fw6q 3131 7 initially initially RB cord-006870-f5w6fw6q 3131 8 very very RB cord-006870-f5w6fw6q 3131 9 low low JJ cord-006870-f5w6fw6q 3131 10 ( ( -LRB- cord-006870-f5w6fw6q 3131 11 evidenced evidence VBN cord-006870-f5w6fw6q 3131 12 by by IN cord-006870-f5w6fw6q 3131 13 marked marked JJ cord-006870-f5w6fw6q 3131 14 increase increase NN cord-006870-f5w6fw6q 3131 15 in in IN cord-006870-f5w6fw6q 3131 16 the the DT cord-006870-f5w6fw6q 3131 17 P2 P2 NNP cord-006870-f5w6fw6q 3131 18 component component NN cord-006870-f5w6fw6q 3131 19 of of IN cord-006870-f5w6fw6q 3131 20 the the DT cord-006870-f5w6fw6q 3131 21 ICP ICP NNP cord-006870-f5w6fw6q 3131 22 waveform waveform NN cord-006870-f5w6fw6q 3131 23 ) ) -RRB- cord-006870-f5w6fw6q 3131 24 , , , cord-006870-f5w6fw6q 3131 25 appeared appear VBD cord-006870-f5w6fw6q 3131 26 to to IN cord-006870-f5w6fw6q 3131 27 paradoxically paradoxically RB cord-006870-f5w6fw6q 3131 28 re re VB cord-006870-f5w6fw6q 3131 29 - - VB cord-006870-f5w6fw6q 3131 30 normalize normalize VB cord-006870-f5w6fw6q 3131 31 as as IN cord-006870-f5w6fw6q 3131 32 the the DT cord-006870-f5w6fw6q 3131 33 recording recording NN cord-006870-f5w6fw6q 3131 34 continued continue VBD cord-006870-f5w6fw6q 3131 35 . . . cord-006870-f5w6fw6q 3132 1 Continuous continuous JJ cord-006870-f5w6fw6q 3132 2 neuromonitoring neuromonitoring NN cord-006870-f5w6fw6q 3132 3 reveals reveal VBZ cord-006870-f5w6fw6q 3132 4 a a DT cord-006870-f5w6fw6q 3132 5 characteristic characteristic JJ cord-006870-f5w6fw6q 3132 6 pattern pattern NN cord-006870-f5w6fw6q 3132 7 of of IN cord-006870-f5w6fw6q 3132 8 cerebrovascular cerebrovascular JJ cord-006870-f5w6fw6q 3132 9 physiologic physiologic JJ cord-006870-f5w6fw6q 3132 10 changes change NNS cord-006870-f5w6fw6q 3132 11 that that WDT cord-006870-f5w6fw6q 3132 12 accompany accompany VBP cord-006870-f5w6fw6q 3132 13 brain brain NN cord-006870-f5w6fw6q 3132 14 death death NN cord-006870-f5w6fw6q 3132 15 . . . cord-006870-f5w6fw6q 3133 1 These these DT cord-006870-f5w6fw6q 3133 2 changes change NNS cord-006870-f5w6fw6q 3133 3 are be VBP cord-006870-f5w6fw6q 3133 4 consistent consistent JJ cord-006870-f5w6fw6q 3133 5 with with IN cord-006870-f5w6fw6q 3133 6 a a DT cord-006870-f5w6fw6q 3133 7 progressive progressive JJ cord-006870-f5w6fw6q 3133 8 cessation cessation NN cord-006870-f5w6fw6q 3133 9 of of IN cord-006870-f5w6fw6q 3133 10 cerebral cerebral JJ cord-006870-f5w6fw6q 3133 11 perfusion perfusion NN cord-006870-f5w6fw6q 3133 12 caused cause VBN cord-006870-f5w6fw6q 3133 13 by by IN cord-006870-f5w6fw6q 3133 14 diffuse diffuse JJ cord-006870-f5w6fw6q 3133 15 cerebral cerebral JJ cord-006870-f5w6fw6q 3133 16 edema edema NN cord-006870-f5w6fw6q 3133 17 . . . cord-006870-f5w6fw6q 3134 1 Although although IN cord-006870-f5w6fw6q 3134 2 not not RB cord-006870-f5w6fw6q 3134 3 currently currently RB cord-006870-f5w6fw6q 3134 4 a a DT cord-006870-f5w6fw6q 3134 5 part part NN cord-006870-f5w6fw6q 3134 6 of of IN cord-006870-f5w6fw6q 3134 7 the the DT cord-006870-f5w6fw6q 3134 8 formal formal JJ cord-006870-f5w6fw6q 3134 9 brain brain NN cord-006870-f5w6fw6q 3134 10 death death NN cord-006870-f5w6fw6q 3134 11 determination determination NN cord-006870-f5w6fw6q 3134 12 process process NN cord-006870-f5w6fw6q 3134 13 , , , cord-006870-f5w6fw6q 3134 14 such such JJ cord-006870-f5w6fw6q 3134 15 monitoring monitoring NN cord-006870-f5w6fw6q 3134 16 could could MD cord-006870-f5w6fw6q 3134 17 be be VB cord-006870-f5w6fw6q 3134 18 helpful helpful JJ cord-006870-f5w6fw6q 3134 19 to to TO cord-006870-f5w6fw6q 3134 20 identify identify VB cord-006870-f5w6fw6q 3134 21 when when WRB cord-006870-f5w6fw6q 3134 22 brain brain NN cord-006870-f5w6fw6q 3134 23 death death NN cord-006870-f5w6fw6q 3134 24 has have VBZ cord-006870-f5w6fw6q 3134 25 truly truly RB cord-006870-f5w6fw6q 3134 26 occurred occur VBN cord-006870-f5w6fw6q 3134 27 . . . cord-006870-f5w6fw6q 3135 1 Automated automated JJ cord-006870-f5w6fw6q 3135 2 devices device NNS cord-006870-f5w6fw6q 3135 3 that that WDT cord-006870-f5w6fw6q 3135 4 collect collect VBP cord-006870-f5w6fw6q 3135 5 objective objective JJ cord-006870-f5w6fw6q 3135 6 quantitative quantitative JJ cord-006870-f5w6fw6q 3135 7 data datum NNS cord-006870-f5w6fw6q 3135 8 on on IN cord-006870-f5w6fw6q 3135 9 pupil pupil NN cord-006870-f5w6fw6q 3135 10 size size NN cord-006870-f5w6fw6q 3135 11 and and CC cord-006870-f5w6fw6q 3135 12 reactivity reactivity NN cord-006870-f5w6fw6q 3135 13 are be VBP cord-006870-f5w6fw6q 3135 14 increasingly increasingly RB cord-006870-f5w6fw6q 3135 15 used use VBN cord-006870-f5w6fw6q 3135 16 for for IN cord-006870-f5w6fw6q 3135 17 critically critically RB cord-006870-f5w6fw6q 3135 18 ill ill JJ cord-006870-f5w6fw6q 3135 19 patients patient NNS cord-006870-f5w6fw6q 3135 20 with with IN cord-006870-f5w6fw6q 3135 21 neurologic neurologic JJ cord-006870-f5w6fw6q 3135 22 disease disease NN cord-006870-f5w6fw6q 3135 23 . . . cord-006870-f5w6fw6q 3136 1 However however RB cord-006870-f5w6fw6q 3136 2 , , , cord-006870-f5w6fw6q 3136 3 there there EX cord-006870-f5w6fw6q 3136 4 is be VBZ cord-006870-f5w6fw6q 3136 5 limited limited JJ cord-006870-f5w6fw6q 3136 6 data datum NNS cord-006870-f5w6fw6q 3136 7 on on IN cord-006870-f5w6fw6q 3136 8 the the DT cord-006870-f5w6fw6q 3136 9 normative normative JJ cord-006870-f5w6fw6q 3136 10 range range NN cord-006870-f5w6fw6q 3136 11 of of IN cord-006870-f5w6fw6q 3136 12 pupillary pupillary JJ cord-006870-f5w6fw6q 3136 13 reactivity reactivity NN cord-006870-f5w6fw6q 3136 14 in in IN cord-006870-f5w6fw6q 3136 15 the the DT cord-006870-f5w6fw6q 3136 16 critically critically RB cord-006870-f5w6fw6q 3136 17 ill ill JJ cord-006870-f5w6fw6q 3136 18 , , , cord-006870-f5w6fw6q 3136 19 and and CC cord-006870-f5w6fw6q 3136 20 the the DT cord-006870-f5w6fw6q 3136 21 relationship relationship NN cord-006870-f5w6fw6q 3136 22 between between IN cord-006870-f5w6fw6q 3136 23 reactivity reactivity NN cord-006870-f5w6fw6q 3136 24 and and CC cord-006870-f5w6fw6q 3136 25 traditional traditional JJ cord-006870-f5w6fw6q 3136 26 monitoring monitoring NN cord-006870-f5w6fw6q 3136 27 metrics metric NNS cord-006870-f5w6fw6q 3136 28 . . . cord-006870-f5w6fw6q 3137 1 To to TO cord-006870-f5w6fw6q 3137 2 determine determine VB cord-006870-f5w6fw6q 3137 3 pupil pupil NN cord-006870-f5w6fw6q 3137 4 characteristics characteristic NNS cord-006870-f5w6fw6q 3137 5 in in IN cord-006870-f5w6fw6q 3137 6 this this DT cord-006870-f5w6fw6q 3137 7 population population NN cord-006870-f5w6fw6q 3137 8 , , , cord-006870-f5w6fw6q 3137 9 we -PRON- PRP cord-006870-f5w6fw6q 3137 10 prospectively prospectively RB cord-006870-f5w6fw6q 3137 11 collected collect VBD cord-006870-f5w6fw6q 3137 12 quantitative quantitative JJ cord-006870-f5w6fw6q 3137 13 pupillometry pupillometry NN cord-006870-f5w6fw6q 3137 14 data datum NNS cord-006870-f5w6fw6q 3137 15 in in IN cord-006870-f5w6fw6q 3137 16 patients patient NNS cord-006870-f5w6fw6q 3137 17 admitted admit VBN cord-006870-f5w6fw6q 3137 18 to to IN cord-006870-f5w6fw6q 3137 19 the the DT cord-006870-f5w6fw6q 3137 20 Neuro Neuro NNP cord-006870-f5w6fw6q 3137 21 ICU ICU NNP cord-006870-f5w6fw6q 3137 22 with with IN cord-006870-f5w6fw6q 3137 23 an an DT cord-006870-f5w6fw6q 3137 24 expected expect VBN cord-006870-f5w6fw6q 3137 25 stay stay NN cord-006870-f5w6fw6q 3137 26 of of IN cord-006870-f5w6fw6q 3137 27 at at RB cord-006870-f5w6fw6q 3137 28 least least RBS cord-006870-f5w6fw6q 3137 29 24 24 CD cord-006870-f5w6fw6q 3137 30 hours hour NNS cord-006870-f5w6fw6q 3137 31 . . . cord-006870-f5w6fw6q 3138 1 Trained trained JJ cord-006870-f5w6fw6q 3138 2 nursing nursing NN cord-006870-f5w6fw6q 3138 3 staff staff NN cord-006870-f5w6fw6q 3138 4 measured measure VBD cord-006870-f5w6fw6q 3138 5 pupillary pupillary JJ cord-006870-f5w6fw6q 3138 6 reactivity reactivity NN cord-006870-f5w6fw6q 3138 7 with with IN cord-006870-f5w6fw6q 3138 8 the the DT cord-006870-f5w6fw6q 3138 9 NeurOptics-200 NeurOptics-200 NNP cord-006870-f5w6fw6q 3138 10 pupillometer pupillometer NN cord-006870-f5w6fw6q 3138 11 device device NN cord-006870-f5w6fw6q 3138 12 every every DT cord-006870-f5w6fw6q 3138 13 2-hours 2-hours CD cord-006870-f5w6fw6q 3138 14 . . . cord-006870-f5w6fw6q 3139 1 Measurements measurement NNS cord-006870-f5w6fw6q 3139 2 included include VBD cord-006870-f5w6fw6q 3139 3 the the DT cord-006870-f5w6fw6q 3139 4 Neurologic Neurologic NNP cord-006870-f5w6fw6q 3139 5 Pupil Pupil NNP cord-006870-f5w6fw6q 3139 6 Index Index NNP cord-006870-f5w6fw6q 3139 7 , , , cord-006870-f5w6fw6q 3139 8 ( ( -LRB- cord-006870-f5w6fw6q 3139 9 NPi NPi NNP cord-006870-f5w6fw6q 3139 10 ) ) -RRB- cord-006870-f5w6fw6q 3139 11 a a DT cord-006870-f5w6fw6q 3139 12 composite composite JJ cord-006870-f5w6fw6q 3139 13 metric metric NN cord-006870-f5w6fw6q 3139 14 ranging range VBG cord-006870-f5w6fw6q 3139 15 from from IN cord-006870-f5w6fw6q 3139 16 0 0 CD cord-006870-f5w6fw6q 3139 17 - - SYM cord-006870-f5w6fw6q 3139 18 5 5 CD cord-006870-f5w6fw6q 3139 19 in in IN cord-006870-f5w6fw6q 3139 20 which which WDT cord-006870-f5w6fw6q 3140 1 > > XX cord-006870-f5w6fw6q 3140 2 3 3 CD cord-006870-f5w6fw6q 3140 3 is be VBZ cord-006870-f5w6fw6q 3140 4 considered consider VBN cord-006870-f5w6fw6q 3140 5 normal normal JJ cord-006870-f5w6fw6q 3140 6 , , , cord-006870-f5w6fw6q 3140 7 resting rest VBG cord-006870-f5w6fw6q 3140 8 and and CC cord-006870-f5w6fw6q 3140 9 constricted constricted JJ cord-006870-f5w6fw6q 3140 10 pupil pupil NN cord-006870-f5w6fw6q 3140 11 size size NN cord-006870-f5w6fw6q 3140 12 , , , cord-006870-f5w6fw6q 3140 13 constriction constriction NN cord-006870-f5w6fw6q 3140 14 velocity velocity NN cord-006870-f5w6fw6q 3140 15 , , , cord-006870-f5w6fw6q 3140 16 dilation dilation NN cord-006870-f5w6fw6q 3140 17 velocity velocity NN cord-006870-f5w6fw6q 3140 18 and and CC cord-006870-f5w6fw6q 3140 19 latency latency NN cord-006870-f5w6fw6q 3140 20 . . . cord-006870-f5w6fw6q 3141 1 These these DT cord-006870-f5w6fw6q 3141 2 recordings recording NNS cord-006870-f5w6fw6q 3141 3 were be VBD cord-006870-f5w6fw6q 3141 4 compared compare VBN cord-006870-f5w6fw6q 3141 5 with with IN cord-006870-f5w6fw6q 3141 6 averaged average VBN cord-006870-f5w6fw6q 3141 7 intracranial intracranial JJ cord-006870-f5w6fw6q 3141 8 pressure pressure NN cord-006870-f5w6fw6q 3141 9 ( ( -LRB- cord-006870-f5w6fw6q 3141 10 ICP ICP NNP cord-006870-f5w6fw6q 3141 11 ) ) -RRB- cord-006870-f5w6fw6q 3141 12 and and CC cord-006870-f5w6fw6q 3141 13 Glasgow Glasgow NNP cord-006870-f5w6fw6q 3141 14 Coma Coma NNP cord-006870-f5w6fw6q 3141 15 Scale Scale NNP cord-006870-f5w6fw6q 3141 16 ( ( -LRB- cord-006870-f5w6fw6q 3141 17 GCS GCS NNP cord-006870-f5w6fw6q 3141 18 ) ) -RRB- cord-006870-f5w6fw6q 3141 19 assessments assessment NNS cord-006870-f5w6fw6q 3141 20 within within IN cord-006870-f5w6fw6q 3141 21 the the DT cord-006870-f5w6fw6q 3141 22 same same JJ cord-006870-f5w6fw6q 3141 23 hour hour NN cord-006870-f5w6fw6q 3141 24 . . . cord-006870-f5w6fw6q 3142 1 We -PRON- PRP cord-006870-f5w6fw6q 3142 2 used use VBD cord-006870-f5w6fw6q 3142 3 univariate univariate JJ cord-006870-f5w6fw6q 3142 4 and and CC cord-006870-f5w6fw6q 3142 5 spearman spearman NNP cord-006870-f5w6fw6q 3142 6 's 's POS cord-006870-f5w6fw6q 3142 7 rank rank NN cord-006870-f5w6fw6q 3142 8 tests test NNS cord-006870-f5w6fw6q 3142 9 to to TO cord-006870-f5w6fw6q 3142 10 explore explore VB cord-006870-f5w6fw6q 3142 11 associations association NNS cord-006870-f5w6fw6q 3142 12 between between IN cord-006870-f5w6fw6q 3142 13 pupil pupil NN cord-006870-f5w6fw6q 3142 14 characteristics characteristic NNS cord-006870-f5w6fw6q 3142 15 and and CC cord-006870-f5w6fw6q 3142 16 clinical clinical JJ cord-006870-f5w6fw6q 3142 17 variables variable NNS cord-006870-f5w6fw6q 3142 18 , , , cord-006870-f5w6fw6q 3142 19 followed follow VBN cord-006870-f5w6fw6q 3142 20 by by IN cord-006870-f5w6fw6q 3142 21 multi multi JJ cord-006870-f5w6fw6q 3142 22 - - JJ cord-006870-f5w6fw6q 3142 23 level level JJ cord-006870-f5w6fw6q 3142 24 linear linear JJ cord-006870-f5w6fw6q 3142 25 regression regression NN cord-006870-f5w6fw6q 3142 26 to to TO cord-006870-f5w6fw6q 3142 27 account account VB cord-006870-f5w6fw6q 3142 28 for for IN cord-006870-f5w6fw6q 3142 29 intra intra NNP cord-006870-f5w6fw6q 3142 30 - - : cord-006870-f5w6fw6q 3142 31 and and CC cord-006870-f5w6fw6q 3142 32 inter inter JJ cord-006870-f5w6fw6q 3142 33 - - JJ cord-006870-f5w6fw6q 3142 34 subject subject JJ cord-006870-f5w6fw6q 3142 35 variability variability NN cord-006870-f5w6fw6q 3142 36 . . . cord-006870-f5w6fw6q 3143 1 One one CD cord-006870-f5w6fw6q 3143 2 - - HYPH cord-006870-f5w6fw6q 3143 3 hundred hundred CD cord-006870-f5w6fw6q 3143 4 patients patient NNS cord-006870-f5w6fw6q 3143 5 underwent undergo VBD cord-006870-f5w6fw6q 3143 6 4200 4200 CD cord-006870-f5w6fw6q 3143 7 paired pair VBN cord-006870-f5w6fw6q 3143 8 observations observation NNS cord-006870-f5w6fw6q 3143 9 . . . cord-006870-f5w6fw6q 3144 1 Fifty fifty CD cord-006870-f5w6fw6q 3144 2 - - HYPH cord-006870-f5w6fw6q 3144 3 five five CD cord-006870-f5w6fw6q 3144 4 patients patient NNS cord-006870-f5w6fw6q 3144 5 had have VBD cord-006870-f5w6fw6q 3144 6 at at RB cord-006870-f5w6fw6q 3144 7 least least RBS cord-006870-f5w6fw6q 3144 8 one one CD cord-006870-f5w6fw6q 3144 9 recorded record VBN cord-006870-f5w6fw6q 3144 10 episode episode NN cord-006870-f5w6fw6q 3144 11 of of IN cord-006870-f5w6fw6q 3144 12 anisocoria anisocoria NNP cord-006870-f5w6fw6q 3144 13 , , , cord-006870-f5w6fw6q 3144 14 27 27 CD cord-006870-f5w6fw6q 3144 15 had have VBD cord-006870-f5w6fw6q 3144 16 low low JJ cord-006870-f5w6fw6q 3144 17 NPis NPis NNP cord-006870-f5w6fw6q 3144 18 in in IN cord-006870-f5w6fw6q 3144 19 more more JJR cord-006870-f5w6fw6q 3144 20 than than IN cord-006870-f5w6fw6q 3144 21 10 10 CD cord-006870-f5w6fw6q 3144 22 % % NN cord-006870-f5w6fw6q 3144 23 of of IN cord-006870-f5w6fw6q 3144 24 recordings recording NNS cord-006870-f5w6fw6q 3144 25 , , , cord-006870-f5w6fw6q 3144 26 and and CC cord-006870-f5w6fw6q 3144 27 29 29 CD cord-006870-f5w6fw6q 3144 28 had have VBD cord-006870-f5w6fw6q 3144 29 normal normal JJ cord-006870-f5w6fw6q 3144 30 pupil pupil NN cord-006870-f5w6fw6q 3144 31 reactivity reactivity NN cord-006870-f5w6fw6q 3144 32 . . . cord-006870-f5w6fw6q 3145 1 Average average JJ cord-006870-f5w6fw6q 3145 2 and and CC cord-006870-f5w6fw6q 3145 3 minimum minimum JJ cord-006870-f5w6fw6q 3145 4 NPi NPi NNS cord-006870-f5w6fw6q 3145 5 was be VBD cord-006870-f5w6fw6q 3145 6 correlated correlate VBN cord-006870-f5w6fw6q 3145 7 with with IN cord-006870-f5w6fw6q 3145 8 average average JJ cord-006870-f5w6fw6q 3145 9 and and CC cord-006870-f5w6fw6q 3145 10 minimum minimum JJ cord-006870-f5w6fw6q 3145 11 recorded record VBN cord-006870-f5w6fw6q 3145 12 hourly hourly JJ cord-006870-f5w6fw6q 3145 13 Glasgow Glasgow NNP cord-006870-f5w6fw6q 3145 14 Coma Coma NNP cord-006870-f5w6fw6q 3145 15 Score Score NNP cord-006870-f5w6fw6q 3145 16 ( ( -LRB- cord-006870-f5w6fw6q 3145 17 GCS GCS NNP cord-006870-f5w6fw6q 3145 18 ) ) -RRB- cord-006870-f5w6fw6q 3145 19 ( ( -LRB- cord-006870-f5w6fw6q 3145 20 p p IN cord-006870-f5w6fw6q 3145 21 values value NNS cord-006870-f5w6fw6q 3145 22 < < XX cord-006870-f5w6fw6q 3145 23 0.001 0.001 CD cord-006870-f5w6fw6q 3145 24 ) ) -RRB- cord-006870-f5w6fw6q 3145 25 . . . cord-006870-f5w6fw6q 3146 1 Increased increase VBN cord-006870-f5w6fw6q 3146 2 asymmetry asymmetry NN cord-006870-f5w6fw6q 3146 3 in in IN cord-006870-f5w6fw6q 3146 4 both both DT cord-006870-f5w6fw6q 3146 5 pupil pupil NN cord-006870-f5w6fw6q 3146 6 size size NN cord-006870-f5w6fw6q 3146 7 ( ( -LRB- cord-006870-f5w6fw6q 3146 8 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 3146 9 ) ) -RRB- cord-006870-f5w6fw6q 3146 10 and and CC cord-006870-f5w6fw6q 3146 11 dilation dilation NN cord-006870-f5w6fw6q 3146 12 velocity velocity NN cord-006870-f5w6fw6q 3146 13 ( ( -LRB- cord-006870-f5w6fw6q 3146 14 p=0.02 p=0.02 NN cord-006870-f5w6fw6q 3146 15 ) ) -RRB- cord-006870-f5w6fw6q 3146 16 was be VBD cord-006870-f5w6fw6q 3146 17 associated associate VBN cord-006870-f5w6fw6q 3146 18 with with IN cord-006870-f5w6fw6q 3146 19 increased increase VBN cord-006870-f5w6fw6q 3146 20 intracranial intracranial JJ cord-006870-f5w6fw6q 3146 21 pressure pressure NN cord-006870-f5w6fw6q 3146 22 ( ( -LRB- cord-006870-f5w6fw6q 3146 23 ICP ICP NNP cord-006870-f5w6fw6q 3146 24 ) ) -RRB- cord-006870-f5w6fw6q 3146 25 . . . cord-006870-f5w6fw6q 3147 1 Anisocoria Anisocoria NNP cord-006870-f5w6fw6q 3147 2 was be VBD cord-006870-f5w6fw6q 3147 3 associated associate VBN cord-006870-f5w6fw6q 3147 4 with with IN cord-006870-f5w6fw6q 3147 5 hyperosmolar hyperosmolar NNP cord-006870-f5w6fw6q 3147 6 therapy therapy NN cord-006870-f5w6fw6q 3147 7 ( ( -LRB- cord-006870-f5w6fw6q 3147 8 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 3147 9 ) ) -RRB- cord-006870-f5w6fw6q 3147 10 . . . cord-006870-f5w6fw6q 3148 1 The the DT cord-006870-f5w6fw6q 3148 2 presence presence NN cord-006870-f5w6fw6q 3148 3 of of IN cord-006870-f5w6fw6q 3148 4 low low JJ cord-006870-f5w6fw6q 3148 5 NPis NPis NNP cord-006870-f5w6fw6q 3148 6 in in IN cord-006870-f5w6fw6q 3148 7 more more JJR cord-006870-f5w6fw6q 3148 8 than than IN cord-006870-f5w6fw6q 3148 9 10 10 CD cord-006870-f5w6fw6q 3148 10 % % NN cord-006870-f5w6fw6q 3148 11 of of IN cord-006870-f5w6fw6q 3148 12 total total JJ cord-006870-f5w6fw6q 3148 13 pupil pupil NN cord-006870-f5w6fw6q 3148 14 measurements measurement NNS cord-006870-f5w6fw6q 3148 15 was be VBD cord-006870-f5w6fw6q 3148 16 associated associate VBN cord-006870-f5w6fw6q 3148 17 with with IN cord-006870-f5w6fw6q 3148 18 death death NN cord-006870-f5w6fw6q 3148 19 at at IN cord-006870-f5w6fw6q 3148 20 discharge discharge NN cord-006870-f5w6fw6q 3148 21 ( ( -LRB- cord-006870-f5w6fw6q 3148 22 p=0.02 p=0.02 NN cord-006870-f5w6fw6q 3148 23 ) ) -RRB- cord-006870-f5w6fw6q 3148 24 . . . cord-006870-f5w6fw6q 3149 1 The the DT cord-006870-f5w6fw6q 3149 2 range range NN cord-006870-f5w6fw6q 3149 3 of of IN cord-006870-f5w6fw6q 3149 4 pupillary pupillary JJ cord-006870-f5w6fw6q 3149 5 metrics metric NNS cord-006870-f5w6fw6q 3149 6 varies vary VBZ cord-006870-f5w6fw6q 3149 7 among among IN cord-006870-f5w6fw6q 3149 8 critically critically RB cord-006870-f5w6fw6q 3149 9 ill ill JJ cord-006870-f5w6fw6q 3149 10 neurologic neurologic JJ cord-006870-f5w6fw6q 3149 11 patients patient NNS cord-006870-f5w6fw6q 3149 12 and and CC cord-006870-f5w6fw6q 3149 13 correlates correlate VBZ cord-006870-f5w6fw6q 3149 14 with with IN cord-006870-f5w6fw6q 3149 15 GCS GCS NNP cord-006870-f5w6fw6q 3149 16 and and CC cord-006870-f5w6fw6q 3149 17 ICP ICP NNP cord-006870-f5w6fw6q 3149 18 . . . cord-006870-f5w6fw6q 3150 1 Further further JJ cord-006870-f5w6fw6q 3150 2 study study NN cord-006870-f5w6fw6q 3150 3 is be VBZ cord-006870-f5w6fw6q 3150 4 needed need VBN cord-006870-f5w6fw6q 3150 5 to to TO cord-006870-f5w6fw6q 3150 6 establish establish VB cord-006870-f5w6fw6q 3150 7 whether whether IN cord-006870-f5w6fw6q 3150 8 change change NN cord-006870-f5w6fw6q 3150 9 in in IN cord-006870-f5w6fw6q 3150 10 pupil pupil NN cord-006870-f5w6fw6q 3150 11 metrics metric NNS cord-006870-f5w6fw6q 3150 12 predict predict VBP cord-006870-f5w6fw6q 3150 13 specific specific JJ cord-006870-f5w6fw6q 3150 14 clinical clinical JJ cord-006870-f5w6fw6q 3150 15 events event NNS cord-006870-f5w6fw6q 3150 16 . . . cord-006870-f5w6fw6q 3151 1 Near near IN cord-006870-f5w6fw6q 3151 2 infrared infrared JJ cord-006870-f5w6fw6q 3151 3 spectroscopy spectroscopy NN cord-006870-f5w6fw6q 3151 4 ( ( -LRB- cord-006870-f5w6fw6q 3151 5 NIRS NIRS NNP cord-006870-f5w6fw6q 3151 6 ) ) -RRB- cord-006870-f5w6fw6q 3151 7 provides provide VBZ cord-006870-f5w6fw6q 3151 8 a a DT cord-006870-f5w6fw6q 3151 9 non non JJ cord-006870-f5w6fw6q 3151 10 - - JJ cord-006870-f5w6fw6q 3151 11 invasive invasive JJ cord-006870-f5w6fw6q 3151 12 measurement measurement NN cord-006870-f5w6fw6q 3151 13 of of IN cord-006870-f5w6fw6q 3151 14 regional regional JJ cord-006870-f5w6fw6q 3151 15 cerebral cerebral JJ cord-006870-f5w6fw6q 3151 16 oxygen oxygen NN cord-006870-f5w6fw6q 3151 17 saturation saturation NN cord-006870-f5w6fw6q 3151 18 ( ( -LRB- cord-006870-f5w6fw6q 3151 19 rSO2 rSO2 NNP cord-006870-f5w6fw6q 3151 20 ) ) -RRB- cord-006870-f5w6fw6q 3151 21 that that WDT cord-006870-f5w6fw6q 3151 22 may may MD cord-006870-f5w6fw6q 3151 23 be be VB cord-006870-f5w6fw6q 3151 24 able able JJ cord-006870-f5w6fw6q 3151 25 to to TO cord-006870-f5w6fw6q 3151 26 detect detect VB cord-006870-f5w6fw6q 3151 27 seizure seizure NN cord-006870-f5w6fw6q 3151 28 activity activity NN cord-006870-f5w6fw6q 3151 29 . . . cord-006870-f5w6fw6q 3152 1 In in IN cord-006870-f5w6fw6q 3152 2 this this DT cord-006870-f5w6fw6q 3152 3 study study NN cord-006870-f5w6fw6q 3152 4 , , , cord-006870-f5w6fw6q 3152 5 we -PRON- PRP cord-006870-f5w6fw6q 3152 6 explored explore VBD cord-006870-f5w6fw6q 3152 7 the the DT cord-006870-f5w6fw6q 3152 8 hypothesis hypothesis NN cord-006870-f5w6fw6q 3152 9 that that IN cord-006870-f5w6fw6q 3152 10 rSO2 rSO2 NNP cord-006870-f5w6fw6q 3152 11 is be VBZ cord-006870-f5w6fw6q 3152 12 lower low JJR cord-006870-f5w6fw6q 3152 13 ipsilateral ipsilateral JJ cord-006870-f5w6fw6q 3152 14 to to IN cord-006870-f5w6fw6q 3152 15 seizures seizure NNS cord-006870-f5w6fw6q 3152 16 or or CC cord-006870-f5w6fw6q 3152 17 epileptiform epileptiform NN cord-006870-f5w6fw6q 3152 18 activity activity NN cord-006870-f5w6fw6q 3152 19 compared compare VBN cord-006870-f5w6fw6q 3152 20 to to IN cord-006870-f5w6fw6q 3152 21 the the DT cord-006870-f5w6fw6q 3152 22 contralateral contralateral JJ cord-006870-f5w6fw6q 3152 23 side side NN cord-006870-f5w6fw6q 3152 24 in in IN cord-006870-f5w6fw6q 3152 25 comatose comatose JJ cord-006870-f5w6fw6q 3152 26 patients patient NNS cord-006870-f5w6fw6q 3152 27 . . . cord-006870-f5w6fw6q 3153 1 Five five CD cord-006870-f5w6fw6q 3153 2 patients patient NNS cord-006870-f5w6fw6q 3153 3 ( ( -LRB- cord-006870-f5w6fw6q 3153 4 2 2 CD cord-006870-f5w6fw6q 3153 5 men man NNS cord-006870-f5w6fw6q 3153 6 and and CC cord-006870-f5w6fw6q 3153 7 3 3 CD cord-006870-f5w6fw6q 3153 8 women woman NNS cord-006870-f5w6fw6q 3153 9 ; ; : cord-006870-f5w6fw6q 3153 10 mean mean VB cord-006870-f5w6fw6q 3153 11 age age NN cord-006870-f5w6fw6q 3153 12 69 69 CD cord-006870-f5w6fw6q 3153 13 ) ) -RRB- cord-006870-f5w6fw6q 3153 14 underwent undergo VBD cord-006870-f5w6fw6q 3153 15 continuous continuous JJ cord-006870-f5w6fw6q 3153 16 electroencephalography electroencephalography NN cord-006870-f5w6fw6q 3153 17 ( ( -LRB- cord-006870-f5w6fw6q 3153 18 cEEG ceeg FW cord-006870-f5w6fw6q 3153 19 ) ) -RRB- cord-006870-f5w6fw6q 3153 20 monitoring monitoring NN cord-006870-f5w6fw6q 3153 21 and and CC cord-006870-f5w6fw6q 3153 22 NIRS NIRS NNP cord-006870-f5w6fw6q 3153 23 recording recording NN cord-006870-f5w6fw6q 3153 24 . . . cord-006870-f5w6fw6q 3154 1 cEEG cEEG NNP cord-006870-f5w6fw6q 3154 2 data datum NNS cord-006870-f5w6fw6q 3154 3 were be VBD cord-006870-f5w6fw6q 3154 4 classified classify VBN cord-006870-f5w6fw6q 3154 5 as as IN cord-006870-f5w6fw6q 3154 6 baseline baseline JJ cord-006870-f5w6fw6q 3154 7 , , , cord-006870-f5w6fw6q 3154 8 epileptiform epileptiform NN cord-006870-f5w6fw6q 3154 9 activity activity NN cord-006870-f5w6fw6q 3154 10 or or CC cord-006870-f5w6fw6q 3154 11 seizure seizure NN cord-006870-f5w6fw6q 3154 12 , , , cord-006870-f5w6fw6q 3154 13 slowing slow VBG cord-006870-f5w6fw6q 3154 14 , , , cord-006870-f5w6fw6q 3154 15 or or CC cord-006870-f5w6fw6q 3154 16 burst burst VB cord-006870-f5w6fw6q 3154 17 suppression suppression NN cord-006870-f5w6fw6q 3154 18 at at IN cord-006870-f5w6fw6q 3154 19 hourly hourly JJ cord-006870-f5w6fw6q 3154 20 intervals interval NNS cord-006870-f5w6fw6q 3154 21 over over IN cord-006870-f5w6fw6q 3154 22 the the DT cord-006870-f5w6fw6q 3154 23 course course NN cord-006870-f5w6fw6q 3154 24 of of IN cord-006870-f5w6fw6q 3154 25 the the DT cord-006870-f5w6fw6q 3154 26 recoding recoding JJ cord-006870-f5w6fw6q 3154 27 period period NN cord-006870-f5w6fw6q 3154 28 ( ( -LRB- cord-006870-f5w6fw6q 3154 29 mean mean JJ cord-006870-f5w6fw6q 3154 30 duration duration NN cord-006870-f5w6fw6q 3154 31 34.1 34.1 CD cord-006870-f5w6fw6q 3154 32 hours hour NNS cord-006870-f5w6fw6q 3154 33 , , , cord-006870-f5w6fw6q 3154 34 range range VBP cord-006870-f5w6fw6q 3154 35 24 24 CD cord-006870-f5w6fw6q 3154 36 to to TO cord-006870-f5w6fw6q 3154 37 85 85 CD cord-006870-f5w6fw6q 3154 38 hours hour NNS cord-006870-f5w6fw6q 3154 39 ) ) -RRB- cord-006870-f5w6fw6q 3154 40 . . . cord-006870-f5w6fw6q 3155 1 Three three CD cord-006870-f5w6fw6q 3155 2 patients patient NNS cord-006870-f5w6fw6q 3155 3 had have VBD cord-006870-f5w6fw6q 3155 4 idiopathic idiopathic JJ cord-006870-f5w6fw6q 3155 5 status status NN cord-006870-f5w6fw6q 3155 6 epilepticus epilepticus NN cord-006870-f5w6fw6q 3155 7 , , , cord-006870-f5w6fw6q 3155 8 two two CD cord-006870-f5w6fw6q 3155 9 had have VBD cord-006870-f5w6fw6q 3155 10 intracranial intracranial JJ cord-006870-f5w6fw6q 3155 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3155 12 , , , cord-006870-f5w6fw6q 3155 13 and and CC cord-006870-f5w6fw6q 3155 14 one one CD cord-006870-f5w6fw6q 3155 15 had have VBD cord-006870-f5w6fw6q 3155 16 a a DT cord-006870-f5w6fw6q 3155 17 temporal temporal JJ cord-006870-f5w6fw6q 3155 18 meningioma meningioma NN cord-006870-f5w6fw6q 3155 19 . . . cord-006870-f5w6fw6q 3156 1 The the DT cord-006870-f5w6fw6q 3156 2 relationship relationship NN cord-006870-f5w6fw6q 3156 3 between between IN cord-006870-f5w6fw6q 3156 4 rSO2 rSO2 NNP cord-006870-f5w6fw6q 3156 5 and and CC cord-006870-f5w6fw6q 3156 6 epileptiform epileptiform NNP cord-006870-f5w6fw6q 3156 7 discharges discharge NNS cord-006870-f5w6fw6q 3156 8 was be VBD cord-006870-f5w6fw6q 3156 9 explored explore VBN cord-006870-f5w6fw6q 3156 10 using use VBG cord-006870-f5w6fw6q 3156 11 scatterplots scatterplot NNS cord-006870-f5w6fw6q 3156 12 . . . cord-006870-f5w6fw6q 3157 1 The the DT cord-006870-f5w6fw6q 3157 2 association association NN cord-006870-f5w6fw6q 3157 3 was be VBD cord-006870-f5w6fw6q 3157 4 assessed assess VBN cord-006870-f5w6fw6q 3157 5 using use VBG cord-006870-f5w6fw6q 3157 6 mixed mixed JJ cord-006870-f5w6fw6q 3157 7 random random JJ cord-006870-f5w6fw6q 3157 8 effects effect NNS cord-006870-f5w6fw6q 3157 9 models model NNS cord-006870-f5w6fw6q 3157 10 with with IN cord-006870-f5w6fw6q 3157 11 a a DT cord-006870-f5w6fw6q 3157 12 random random JJ cord-006870-f5w6fw6q 3157 13 intercept intercept NN cord-006870-f5w6fw6q 3157 14 . . . cord-006870-f5w6fw6q 3158 1 An an DT cord-006870-f5w6fw6q 3158 2 independent independent JJ cord-006870-f5w6fw6q 3158 3 within within IN cord-006870-f5w6fw6q 3158 4 - - HYPH cord-006870-f5w6fw6q 3158 5 subject subject NN cord-006870-f5w6fw6q 3158 6 residual residual JJ cord-006870-f5w6fw6q 3158 7 structure structure NN cord-006870-f5w6fw6q 3158 8 was be VBD cord-006870-f5w6fw6q 3158 9 used use VBN cord-006870-f5w6fw6q 3158 10 . . . cord-006870-f5w6fw6q 3159 1 There there EX cord-006870-f5w6fw6q 3159 2 were be VBD cord-006870-f5w6fw6q 3159 3 127 127 CD cord-006870-f5w6fw6q 3159 4 measurements measurement NNS cord-006870-f5w6fw6q 3159 5 with with IN cord-006870-f5w6fw6q 3159 6 cEEG ceeg NN cord-006870-f5w6fw6q 3159 7 and and CC cord-006870-f5w6fw6q 3159 8 NIRS nirs NN cord-006870-f5w6fw6q 3159 9 from from IN cord-006870-f5w6fw6q 3159 10 5 5 CD cord-006870-f5w6fw6q 3159 11 patients patient NNS cord-006870-f5w6fw6q 3159 12 . . . cord-006870-f5w6fw6q 3160 1 One one CD cord-006870-f5w6fw6q 3160 2 patient patient NN cord-006870-f5w6fw6q 3160 3 was be VBD cord-006870-f5w6fw6q 3160 4 excluded exclude VBN cord-006870-f5w6fw6q 3160 5 as as IN cord-006870-f5w6fw6q 3160 6 the the DT cord-006870-f5w6fw6q 3160 7 NIRS NIRS NNP cord-006870-f5w6fw6q 3160 8 sensors sensor NNS cord-006870-f5w6fw6q 3160 9 were be VBD cord-006870-f5w6fw6q 3160 10 potentially potentially RB cord-006870-f5w6fw6q 3160 11 reversed reverse VBN cord-006870-f5w6fw6q 3160 12 . . . cord-006870-f5w6fw6q 3161 1 Epileptiform epileptiform NN cord-006870-f5w6fw6q 3161 2 activity activity NN cord-006870-f5w6fw6q 3161 3 or or CC cord-006870-f5w6fw6q 3161 4 seizures seizure NNS cord-006870-f5w6fw6q 3161 5 were be VBD cord-006870-f5w6fw6q 3161 6 observed observe VBN cord-006870-f5w6fw6q 3161 7 in in IN cord-006870-f5w6fw6q 3161 8 a a DT cord-006870-f5w6fw6q 3161 9 median median NN cord-006870-f5w6fw6q 3161 10 of of IN cord-006870-f5w6fw6q 3161 11 37 37 CD cord-006870-f5w6fw6q 3161 12 % % NN cord-006870-f5w6fw6q 3161 13 of of IN cord-006870-f5w6fw6q 3161 14 the the DT cord-006870-f5w6fw6q 3161 15 measurements measurement NNS cord-006870-f5w6fw6q 3161 16 ( ( -LRB- cord-006870-f5w6fw6q 3161 17 IQR IQR NNP cord-006870-f5w6fw6q 3161 18 23 23 CD cord-006870-f5w6fw6q 3161 19 - - SYM cord-006870-f5w6fw6q 3161 20 62 62 CD cord-006870-f5w6fw6q 3161 21 % % NN cord-006870-f5w6fw6q 3161 22 ) ) -RRB- cord-006870-f5w6fw6q 3161 23 . . . cord-006870-f5w6fw6q 3162 1 rSO2 rSO2 NNP cord-006870-f5w6fw6q 3162 2 was be VBD cord-006870-f5w6fw6q 3162 3 significantly significantly RB cord-006870-f5w6fw6q 3162 4 lower low JJR cord-006870-f5w6fw6q 3162 5 on on IN cord-006870-f5w6fw6q 3162 6 the the DT cord-006870-f5w6fw6q 3162 7 side side NN cord-006870-f5w6fw6q 3162 8 ipsilateral ipsilateral JJ cord-006870-f5w6fw6q 3162 9 to to IN cord-006870-f5w6fw6q 3162 10 seizures seizure NNS cord-006870-f5w6fw6q 3162 11 -5.19 -5.19 ADD cord-006870-f5w6fw6q 3162 12 , , , cord-006870-f5w6fw6q 3162 13 p p NN cord-006870-f5w6fw6q 3162 14 < < XX cord-006870-f5w6fw6q 3162 15 0.001 0.001 CD cord-006870-f5w6fw6q 3162 16 ) ) -RRB- cord-006870-f5w6fw6q 3162 17 after after IN cord-006870-f5w6fw6q 3162 18 adjusting adjust VBG cord-006870-f5w6fw6q 3162 19 for for IN cord-006870-f5w6fw6q 3162 20 MAP MAP NNP cord-006870-f5w6fw6q 3162 21 . . . cord-006870-f5w6fw6q 3163 1 All all DT cord-006870-f5w6fw6q 3163 2 patients patient NNS cord-006870-f5w6fw6q 3163 3 only only RB cord-006870-f5w6fw6q 3163 4 had have VBD cord-006870-f5w6fw6q 3163 5 partial partial JJ cord-006870-f5w6fw6q 3163 6 seizures seizure NNS cord-006870-f5w6fw6q 3163 7 with with IN cord-006870-f5w6fw6q 3163 8 no no DT cord-006870-f5w6fw6q 3163 9 generalization generalization NN cord-006870-f5w6fw6q 3163 10 . . . cord-006870-f5w6fw6q 3164 1 Partial partial JJ cord-006870-f5w6fw6q 3164 2 seizures seizure NNS cord-006870-f5w6fw6q 3165 1 and/or and/or CC cord-006870-f5w6fw6q 3165 2 epileptiform epileptiform NNP cord-006870-f5w6fw6q 3165 3 discharges discharge NNS cord-006870-f5w6fw6q 3165 4 were be VBD cord-006870-f5w6fw6q 3165 5 not not RB cord-006870-f5w6fw6q 3165 6 associated associate VBN cord-006870-f5w6fw6q 3165 7 with with IN cord-006870-f5w6fw6q 3165 8 impaired impaired JJ cord-006870-f5w6fw6q 3165 9 autoregulation autoregulation NN cord-006870-f5w6fw6q 3165 10 . . . cord-006870-f5w6fw6q 3166 1 We -PRON- PRP cord-006870-f5w6fw6q 3166 2 found find VBD cord-006870-f5w6fw6q 3166 3 a a DT cord-006870-f5w6fw6q 3166 4 significant significant JJ cord-006870-f5w6fw6q 3166 5 lower low JJR cord-006870-f5w6fw6q 3166 6 cerebral cerebral JJ cord-006870-f5w6fw6q 3166 7 oxygen oxygen NN cord-006870-f5w6fw6q 3166 8 saturation saturation NN cord-006870-f5w6fw6q 3166 9 ipsilateral ipsilateral JJ cord-006870-f5w6fw6q 3166 10 to to IN cord-006870-f5w6fw6q 3166 11 seizures seizure NNS cord-006870-f5w6fw6q 3166 12 and/or and/or CC cord-006870-f5w6fw6q 3166 13 epileptiform epileptiform NN cord-006870-f5w6fw6q 3166 14 activity activity NN cord-006870-f5w6fw6q 3166 15 . . . cord-006870-f5w6fw6q 3167 1 The the DT cord-006870-f5w6fw6q 3167 2 association association NN cord-006870-f5w6fw6q 3167 3 was be VBD cord-006870-f5w6fw6q 3167 4 observed observe VBN cord-006870-f5w6fw6q 3167 5 in in IN cord-006870-f5w6fw6q 3167 6 patients patient NNS cord-006870-f5w6fw6q 3167 7 with with IN cord-006870-f5w6fw6q 3167 8 various various JJ cord-006870-f5w6fw6q 3167 9 etiologies etiology NNS cord-006870-f5w6fw6q 3167 10 of of IN cord-006870-f5w6fw6q 3167 11 coma coma NN cord-006870-f5w6fw6q 3167 12 , , , cord-006870-f5w6fw6q 3167 13 and and CC cord-006870-f5w6fw6q 3167 14 with with IN cord-006870-f5w6fw6q 3167 15 either either CC cord-006870-f5w6fw6q 3167 16 convulsive convulsive JJ cord-006870-f5w6fw6q 3167 17 and and CC cord-006870-f5w6fw6q 3167 18 non non JJ cord-006870-f5w6fw6q 3167 19 - - JJ cord-006870-f5w6fw6q 3167 20 convulsive convulsive JJ cord-006870-f5w6fw6q 3167 21 seizures seizure NNS cord-006870-f5w6fw6q 3167 22 . . . cord-006870-f5w6fw6q 3168 1 Decreases decrease NNS cord-006870-f5w6fw6q 3168 2 of of IN cord-006870-f5w6fw6q 3168 3 regional regional JJ cord-006870-f5w6fw6q 3168 4 cerebral cerebral JJ cord-006870-f5w6fw6q 3168 5 oxygen oxygen NN cord-006870-f5w6fw6q 3168 6 saturation saturation NN cord-006870-f5w6fw6q 3168 7 at at IN cord-006870-f5w6fw6q 3168 8 the the DT cord-006870-f5w6fw6q 3168 9 bedside bedside NN cord-006870-f5w6fw6q 3168 10 may may MD cord-006870-f5w6fw6q 3168 11 alert alert VB cord-006870-f5w6fw6q 3168 12 the the DT cord-006870-f5w6fw6q 3168 13 clinician clinician NN cord-006870-f5w6fw6q 3168 14 of of IN cord-006870-f5w6fw6q 3168 15 ipsilateral ipsilateral JJ cord-006870-f5w6fw6q 3168 16 seizures seizure NNS cord-006870-f5w6fw6q 3168 17 . . . cord-006870-f5w6fw6q 3169 1 Elevated elevated JJ cord-006870-f5w6fw6q 3169 2 intracranial intracranial JJ cord-006870-f5w6fw6q 3169 3 pressure pressure NN cord-006870-f5w6fw6q 3169 4 ( ( -LRB- cord-006870-f5w6fw6q 3169 5 ICP ICP NNP cord-006870-f5w6fw6q 3169 6 ) ) -RRB- cord-006870-f5w6fw6q 3169 7 and and CC cord-006870-f5w6fw6q 3169 8 cerebral cerebral JJ cord-006870-f5w6fw6q 3169 9 edema edema NN cord-006870-f5w6fw6q 3169 10 are be VBP cord-006870-f5w6fw6q 3169 11 common common JJ cord-006870-f5w6fw6q 3169 12 causes cause NNS cord-006870-f5w6fw6q 3169 13 of of IN cord-006870-f5w6fw6q 3169 14 mortality mortality NN cord-006870-f5w6fw6q 3169 15 in in IN cord-006870-f5w6fw6q 3169 16 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3169 17 - - HYPH cord-006870-f5w6fw6q 3169 18 care care NN cord-006870-f5w6fw6q 3169 19 patients patient NNS cord-006870-f5w6fw6q 3169 20 . . . cord-006870-f5w6fw6q 3170 1 Key key JJ cord-006870-f5w6fw6q 3170 2 monitoring monitoring NN cord-006870-f5w6fw6q 3170 3 techniques technique NNS cord-006870-f5w6fw6q 3170 4 for for IN cord-006870-f5w6fw6q 3170 5 ICP ICP NNP cord-006870-f5w6fw6q 3170 6 - - HYPH cord-006870-f5w6fw6q 3170 7 elevation elevation NN cord-006870-f5w6fw6q 3170 8 include include VBP cord-006870-f5w6fw6q 3170 9 neuroimaging neuroimage VBG cord-006870-f5w6fw6q 3170 10 and and CC cord-006870-f5w6fw6q 3170 11 invasive invasive JJ cord-006870-f5w6fw6q 3170 12 ICP ICP NNP cord-006870-f5w6fw6q 3170 13 - - HYPH cord-006870-f5w6fw6q 3170 14 measurement measurement NN cord-006870-f5w6fw6q 3170 15 . . . cord-006870-f5w6fw6q 3171 1 Examination examination NN cord-006870-f5w6fw6q 3171 2 of of IN cord-006870-f5w6fw6q 3171 3 the the DT cord-006870-f5w6fw6q 3171 4 pupils pupil NNS cord-006870-f5w6fw6q 3171 5 is be VBZ cord-006870-f5w6fw6q 3171 6 routinely routinely RB cord-006870-f5w6fw6q 3171 7 performed perform VBN cord-006870-f5w6fw6q 3171 8 to to TO cord-006870-f5w6fw6q 3171 9 determine determine VB cord-006870-f5w6fw6q 3171 10 disturbances disturbance NNS cord-006870-f5w6fw6q 3171 11 within within IN cord-006870-f5w6fw6q 3171 12 cerebral cerebral JJ cord-006870-f5w6fw6q 3171 13 physiology physiology NN cord-006870-f5w6fw6q 3171 14 but but CC cord-006870-f5w6fw6q 3171 15 shows show VBZ cord-006870-f5w6fw6q 3171 16 high high JJ cord-006870-f5w6fw6q 3171 17 inter inter JJ cord-006870-f5w6fw6q 3171 18 - - JJ cord-006870-f5w6fw6q 3171 19 rater rater JJ cord-006870-f5w6fw6q 3171 20 variability variability NN cord-006870-f5w6fw6q 3171 21 . . . cord-006870-f5w6fw6q 3172 1 Portable portable JJ cord-006870-f5w6fw6q 3172 2 infrared infrared JJ cord-006870-f5w6fw6q 3172 3 pupillometry pupillometry NN cord-006870-f5w6fw6q 3172 4 is be VBZ cord-006870-f5w6fw6q 3172 5 increasingly increasingly RB cord-006870-f5w6fw6q 3172 6 used use VBN cord-006870-f5w6fw6q 3172 7 for for IN cord-006870-f5w6fw6q 3172 8 accurate accurate JJ cord-006870-f5w6fw6q 3172 9 measurements measurement NNS cord-006870-f5w6fw6q 3172 10 . . . cord-006870-f5w6fw6q 3173 1 The the DT cord-006870-f5w6fw6q 3173 2 benefit benefit NN cord-006870-f5w6fw6q 3173 3 of of IN cord-006870-f5w6fw6q 3173 4 these these DT cord-006870-f5w6fw6q 3173 5 technique technique NN cord-006870-f5w6fw6q 3173 6 remains remain VBZ cord-006870-f5w6fw6q 3173 7 to to TO cord-006870-f5w6fw6q 3173 8 be be VB cord-006870-f5w6fw6q 3173 9 established establish VBN cord-006870-f5w6fw6q 3173 10 in in IN cord-006870-f5w6fw6q 3173 11 patients patient NNS cord-006870-f5w6fw6q 3173 12 with with IN cord-006870-f5w6fw6q 3173 13 elevated elevated JJ cord-006870-f5w6fw6q 3173 14 ICP ICP NNP cord-006870-f5w6fw6q 3173 15 . . . cord-006870-f5w6fw6q 3174 1 Aim aim VB cord-006870-f5w6fw6q 3174 2 of of IN cord-006870-f5w6fw6q 3174 3 this this DT cord-006870-f5w6fw6q 3174 4 study study NN cord-006870-f5w6fw6q 3174 5 was be VBD cord-006870-f5w6fw6q 3174 6 identify identify VB cord-006870-f5w6fw6q 3174 7 pupillary pupillary JJ cord-006870-f5w6fw6q 3174 8 parameters parameter NNS cord-006870-f5w6fw6q 3174 9 associated associate VBN cord-006870-f5w6fw6q 3174 10 with with IN cord-006870-f5w6fw6q 3174 11 ICPcrisis icpcrisis NN cord-006870-f5w6fw6q 3174 12 in in IN cord-006870-f5w6fw6q 3174 13 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3174 14 - - HYPH cord-006870-f5w6fw6q 3174 15 care care NN cord-006870-f5w6fw6q 3174 16 patients patient NNS cord-006870-f5w6fw6q 3174 17 . . . cord-006870-f5w6fw6q 3175 1 We -PRON- PRP cord-006870-f5w6fw6q 3175 2 prospectively prospectively RB cord-006870-f5w6fw6q 3175 3 enrolled enrol VBD cord-006870-f5w6fw6q 3175 4 31 31 CD cord-006870-f5w6fw6q 3175 5 critically critically RB cord-006870-f5w6fw6q 3175 6 - - HYPH cord-006870-f5w6fw6q 3175 7 ill ill JJ cord-006870-f5w6fw6q 3175 8 patients patient NNS cord-006870-f5w6fw6q 3175 9 ( ( -LRB- cord-006870-f5w6fw6q 3176 1 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3176 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3176 3 / / SYM cord-006870-f5w6fw6q 3176 4 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3176 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3176 6 / / SYM cord-006870-f5w6fw6q 3176 7 stroke/ stroke/ CD cord-006870-f5w6fw6q 3177 1 bacterial bacterial JJ cord-006870-f5w6fw6q 3177 2 meningitis meningitis NN cord-006870-f5w6fw6q 3177 3 ) ) -RRB- cord-006870-f5w6fw6q 3177 4 admitted admit VBD cord-006870-f5w6fw6q 3177 5 to to IN cord-006870-f5w6fw6q 3177 6 our -PRON- PRP$ cord-006870-f5w6fw6q 3177 7 neurointensive neurointensive NN cord-006870-f5w6fw6q 3177 8 care care NN cord-006870-f5w6fw6q 3177 9 unit(07/2016 unit(07/2016 RB cord-006870-f5w6fw6q 3177 10 - - : cord-006870-f5w6fw6q 3177 11 07/2017 07/2017 CD cord-006870-f5w6fw6q 3177 12 ) ) -RRB- cord-006870-f5w6fw6q 3177 13 who who WP cord-006870-f5w6fw6q 3177 14 required require VBD cord-006870-f5w6fw6q 3177 15 placement placement NN cord-006870-f5w6fw6q 3177 16 of of IN cord-006870-f5w6fw6q 3177 17 external external JJ cord-006870-f5w6fw6q 3177 18 ventricular ventricular JJ cord-006870-f5w6fw6q 3177 19 drains drain NNS cord-006870-f5w6fw6q 3177 20 . . . cord-006870-f5w6fw6q 3178 1 We -PRON- PRP cord-006870-f5w6fw6q 3178 2 recorded record VBD cord-006870-f5w6fw6q 3178 3 serial serial JJ cord-006870-f5w6fw6q 3178 4 pupillometer pupillometer NN cord-006870-f5w6fw6q 3178 5 readings reading NNS cord-006870-f5w6fw6q 3178 6 [ [ -LRB- cord-006870-f5w6fw6q 3178 7 i.e. i.e. FW cord-006870-f5w6fw6q 3178 8 maximum maximum JJ cord-006870-f5w6fw6q 3178 9 / / SYM cord-006870-f5w6fw6q 3178 10 minimum minimum NN cord-006870-f5w6fw6q 3178 11 apertures(mm apertures(mm CD cord-006870-f5w6fw6q 3178 12 ) ) -RRB- cord-006870-f5w6fw6q 3178 13 , , , cord-006870-f5w6fw6q 3178 14 constriction constriction NN cord-006870-f5w6fw6q 3178 15 / / SYM cord-006870-f5w6fw6q 3178 16 dilation dilation NN cord-006870-f5w6fw6q 3178 17 velocities(mm velocities(mm NNS cord-006870-f5w6fw6q 3178 18 / / SYM cord-006870-f5w6fw6q 3178 19 sec sec NNP cord-006870-f5w6fw6q 3178 20 . . . cord-006870-f5w6fw6q 3178 21 ) ) -RRB- cord-006870-f5w6fw6q 3178 22 , , , cord-006870-f5w6fw6q 3178 23 latency latency NNP cord-006870-f5w6fw6q 3178 24 period(sec period(sec NNP cord-006870-f5w6fw6q 3178 25 . . . cord-006870-f5w6fw6q 3178 26 ) ) -RRB- cord-006870-f5w6fw6q 3178 27 ] ] -RRB- cord-006870-f5w6fw6q 3178 28 and and CC cord-006870-f5w6fw6q 3178 29 corresponding correspond VBG cord-006870-f5w6fw6q 3178 30 ICP ICP NNP cord-006870-f5w6fw6q 3178 31 values value NNS cord-006870-f5w6fw6q 3178 32 every every DT cord-006870-f5w6fw6q 3178 33 3 3 CD cord-006870-f5w6fw6q 3178 34 hours hour NNS cord-006870-f5w6fw6q 3178 35 after after IN cord-006870-f5w6fw6q 3178 36 admission admission NN cord-006870-f5w6fw6q 3178 37 . . . cord-006870-f5w6fw6q 3179 1 Neurological Neurological NNP cord-006870-f5w6fw6q 3179 2 Pupil Pupil NNP cord-006870-f5w6fw6q 3179 3 index(NPi index(NPi NNP cord-006870-f5w6fw6q 3179 4 ) ) -RRB- cord-006870-f5w6fw6q 3179 5 , , , cord-006870-f5w6fw6q 3179 6 an an DT cord-006870-f5w6fw6q 3179 7 algorithm algorithm NN cord-006870-f5w6fw6q 3179 8 that that WDT cord-006870-f5w6fw6q 3179 9 compares compare VBZ cord-006870-f5w6fw6q 3179 10 above above RB cord-006870-f5w6fw6q 3179 11 mentioned mention VBD cord-006870-f5w6fw6q 3179 12 pupillary pupillary JJ cord-006870-f5w6fw6q 3179 13 parameters parameter NNS cord-006870-f5w6fw6q 3179 14 to to IN cord-006870-f5w6fw6q 3179 15 a a DT cord-006870-f5w6fw6q 3179 16 normative normative JJ cord-006870-f5w6fw6q 3179 17 model model NN cord-006870-f5w6fw6q 3179 18 of of IN cord-006870-f5w6fw6q 3179 19 pupil pupil NN cord-006870-f5w6fw6q 3179 20 reaction reaction NN cord-006870-f5w6fw6q 3179 21 to to IN cord-006870-f5w6fw6q 3179 22 light light NN cord-006870-f5w6fw6q 3179 23 , , , cord-006870-f5w6fw6q 3179 24 grades grade NNS cord-006870-f5w6fw6q 3179 25 pupil pupil NN cord-006870-f5w6fw6q 3179 26 - - HYPH cord-006870-f5w6fw6q 3179 27 function function NN cord-006870-f5w6fw6q 3179 28 on on IN cord-006870-f5w6fw6q 3179 29 a a DT cord-006870-f5w6fw6q 3179 30 scale scale NN cord-006870-f5w6fw6q 3179 31 of of IN cord-006870-f5w6fw6q 3179 32 0(nonreactive 0(nonreactive CD cord-006870-f5w6fw6q 3179 33 ) ) -RRB- cord-006870-f5w6fw6q 3179 34 to to IN cord-006870-f5w6fw6q 3179 35 5(normal 5(normal CD cord-006870-f5w6fw6q 3179 36 ) ) -RRB- cord-006870-f5w6fw6q 3179 37 . . . cord-006870-f5w6fw6q 3180 1 Receiver Receiver NNP cord-006870-f5w6fw6q 3180 2 Operating Operating NNP cord-006870-f5w6fw6q 3180 3 Characteristic(ROC Characteristic(ROC NNP cord-006870-f5w6fw6q 3180 4 ) ) -RRB- cord-006870-f5w6fw6q 3180 5 Curve Curve NNP cord-006870-f5w6fw6q 3180 6 Analysis Analysis NNP cord-006870-f5w6fw6q 3180 7 was be VBD cord-006870-f5w6fw6q 3180 8 performed perform VBN cord-006870-f5w6fw6q 3180 9 to to TO cord-006870-f5w6fw6q 3180 10 investigate investigate VB cord-006870-f5w6fw6q 3180 11 associations association NNS cord-006870-f5w6fw6q 3180 12 between between IN cord-006870-f5w6fw6q 3180 13 pupillary pupillary JJ cord-006870-f5w6fw6q 3180 14 parameters parameter NNS cord-006870-f5w6fw6q 3180 15 and and CC cord-006870-f5w6fw6q 3180 16 presence presence NN cord-006870-f5w6fw6q 3180 17 of of IN cord-006870-f5w6fw6q 3180 18 ICPcrisis(ICP>20mmHg icpcrisis(icp>20mmhg CD cord-006870-f5w6fw6q 3180 19 ) ) -RRB- cord-006870-f5w6fw6q 3180 20 . . . cord-006870-f5w6fw6q 3181 1 In in IN cord-006870-f5w6fw6q 3181 2 31 31 CD cord-006870-f5w6fw6q 3181 3 _SP cord-006870-f5w6fw6q 3182 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3182 2 data datum NNS cord-006870-f5w6fw6q 3182 3 suggest suggest VBP cord-006870-f5w6fw6q 3182 4 a a DT cord-006870-f5w6fw6q 3182 5 relationship relationship NN cord-006870-f5w6fw6q 3182 6 between between IN cord-006870-f5w6fw6q 3182 7 non non AFX cord-006870-f5w6fw6q 3182 8 - - JJ cord-006870-f5w6fw6q 3182 9 invasively invasively RB cord-006870-f5w6fw6q 3182 10 detected detect VBN cord-006870-f5w6fw6q 3182 11 changes change NNS cord-006870-f5w6fw6q 3182 12 in in IN cord-006870-f5w6fw6q 3182 13 NPi NPi NNS cord-006870-f5w6fw6q 3182 14 , , , cord-006870-f5w6fw6q 3182 15 CV CV NNP cord-006870-f5w6fw6q 3182 16 or or CC cord-006870-f5w6fw6q 3182 17 MCV MCV NNP cord-006870-f5w6fw6q 3182 18 and and CC cord-006870-f5w6fw6q 3182 19 ICPcrisis ICPcrisis NNP cord-006870-f5w6fw6q 3182 20 . . . cord-006870-f5w6fw6q 3183 1 Yet yet RB cord-006870-f5w6fw6q 3183 2 , , , cord-006870-f5w6fw6q 3183 3 clinical clinical JJ cord-006870-f5w6fw6q 3183 4 benefit benefit NN cord-006870-f5w6fw6q 3183 5 of of IN cord-006870-f5w6fw6q 3183 6 these these DT cord-006870-f5w6fw6q 3183 7 parameters parameter NNS cord-006870-f5w6fw6q 3183 8 is be VBZ cord-006870-f5w6fw6q 3183 9 subject subject JJ cord-006870-f5w6fw6q 3183 10 to to IN cord-006870-f5w6fw6q 3183 11 future future JJ cord-006870-f5w6fw6q 3183 12 studies study NNS cord-006870-f5w6fw6q 3183 13 . . . cord-006870-f5w6fw6q 3184 1 Lung lung NN cord-006870-f5w6fw6q 3184 2 injury injury NN cord-006870-f5w6fw6q 3184 3 is be VBZ cord-006870-f5w6fw6q 3184 4 frequently frequently RB cord-006870-f5w6fw6q 3184 5 observed observe VBN cord-006870-f5w6fw6q 3184 6 in in IN cord-006870-f5w6fw6q 3184 7 patients patient NNS cord-006870-f5w6fw6q 3184 8 with with IN cord-006870-f5w6fw6q 3184 9 severe severe JJ cord-006870-f5w6fw6q 3184 10 , , , cord-006870-f5w6fw6q 3184 11 acute acute JJ cord-006870-f5w6fw6q 3184 12 brain brain NN cord-006870-f5w6fw6q 3184 13 injury injury NN cord-006870-f5w6fw6q 3184 14 . . . cord-006870-f5w6fw6q 3185 1 While while IN cord-006870-f5w6fw6q 3185 2 these these DT cord-006870-f5w6fw6q 3185 3 patients patient NNS cord-006870-f5w6fw6q 3185 4 often often RB cord-006870-f5w6fw6q 3185 5 require require VBP cord-006870-f5w6fw6q 3185 6 mechanical mechanical JJ cord-006870-f5w6fw6q 3185 7 ventilation ventilation NN cord-006870-f5w6fw6q 3185 8 , , , cord-006870-f5w6fw6q 3185 9 a a DT cord-006870-f5w6fw6q 3185 10 lung lung NN cord-006870-f5w6fw6q 3185 11 protective protective JJ cord-006870-f5w6fw6q 3185 12 ventilation ventilation NN cord-006870-f5w6fw6q 3185 13 strategy strategy NN cord-006870-f5w6fw6q 3185 14 has have VBZ cord-006870-f5w6fw6q 3185 15 not not RB cord-006870-f5w6fw6q 3185 16 been be VBN cord-006870-f5w6fw6q 3185 17 extensively extensively RB cord-006870-f5w6fw6q 3185 18 studied study VBN cord-006870-f5w6fw6q 3185 19 . . . cord-006870-f5w6fw6q 3186 1 This this DT cord-006870-f5w6fw6q 3186 2 may may MD cord-006870-f5w6fw6q 3186 3 be be VB cord-006870-f5w6fw6q 3186 4 due due JJ cord-006870-f5w6fw6q 3186 5 , , , cord-006870-f5w6fw6q 3186 6 in in IN cord-006870-f5w6fw6q 3186 7 part part NN cord-006870-f5w6fw6q 3186 8 , , , cord-006870-f5w6fw6q 3186 9 to to IN cord-006870-f5w6fw6q 3186 10 concerns concern NNS cord-006870-f5w6fw6q 3186 11 that that IN cord-006870-f5w6fw6q 3186 12 elevated elevate VBD cord-006870-f5w6fw6q 3186 13 positive positive JJ cord-006870-f5w6fw6q 3186 14 end end NN cord-006870-f5w6fw6q 3186 15 - - HYPH cord-006870-f5w6fw6q 3186 16 expiratory expiratory NN cord-006870-f5w6fw6q 3186 17 pressure pressure NN cord-006870-f5w6fw6q 3186 18 ( ( -LRB- cord-006870-f5w6fw6q 3186 19 PEEP peep NN cord-006870-f5w6fw6q 3186 20 ) ) -RRB- cord-006870-f5w6fw6q 3186 21 could could MD cord-006870-f5w6fw6q 3186 22 adversely adversely RB cord-006870-f5w6fw6q 3186 23 affect affect VB cord-006870-f5w6fw6q 3186 24 intracranial intracranial JJ cord-006870-f5w6fw6q 3186 25 pressure pressure NN cord-006870-f5w6fw6q 3186 26 ( ( -LRB- cord-006870-f5w6fw6q 3186 27 ICP ICP NNP cord-006870-f5w6fw6q 3186 28 ) ) -RRB- cord-006870-f5w6fw6q 3186 29 or or CC cord-006870-f5w6fw6q 3186 30 cerebral cerebral JJ cord-006870-f5w6fw6q 3186 31 perfusion perfusion NN cord-006870-f5w6fw6q 3186 32 pressure pressure NN cord-006870-f5w6fw6q 3186 33 ( ( -LRB- cord-006870-f5w6fw6q 3186 34 CPP CPP NNP cord-006870-f5w6fw6q 3186 35 ) ) -RRB- cord-006870-f5w6fw6q 3186 36 . . . cord-006870-f5w6fw6q 3187 1 We -PRON- PRP cord-006870-f5w6fw6q 3187 2 were be VBD cord-006870-f5w6fw6q 3187 3 interested interested JJ cord-006870-f5w6fw6q 3187 4 in in IN cord-006870-f5w6fw6q 3187 5 exploring explore VBG cord-006870-f5w6fw6q 3187 6 this this DT cord-006870-f5w6fw6q 3187 7 relationship relationship NN cord-006870-f5w6fw6q 3187 8 as as IN cord-006870-f5w6fw6q 3187 9 a a DT cord-006870-f5w6fw6q 3187 10 first first JJ cord-006870-f5w6fw6q 3187 11 step step NN cord-006870-f5w6fw6q 3187 12 towards towards IN cord-006870-f5w6fw6q 3187 13 understanding understand VBG cord-006870-f5w6fw6q 3187 14 whether whether IN cord-006870-f5w6fw6q 3187 15 mechanical mechanical JJ cord-006870-f5w6fw6q 3187 16 ventilation ventilation NN cord-006870-f5w6fw6q 3187 17 resulted result VBD cord-006870-f5w6fw6q 3187 18 in in IN cord-006870-f5w6fw6q 3187 19 a a DT cord-006870-f5w6fw6q 3187 20 transmission transmission NN cord-006870-f5w6fw6q 3187 21 of of IN cord-006870-f5w6fw6q 3187 22 pressure pressure NN cord-006870-f5w6fw6q 3187 23 to to IN cord-006870-f5w6fw6q 3187 24 the the DT cord-006870-f5w6fw6q 3187 25 brain brain NN cord-006870-f5w6fw6q 3187 26 . . . cord-006870-f5w6fw6q 3188 1 8) 8) NNP cord-006870-f5w6fw6q 3189 1 and and CC cord-006870-f5w6fw6q 3189 2 received receive VBD cord-006870-f5w6fw6q 3190 1 both both DT cord-006870-f5w6fw6q 3190 2 mechanical mechanical JJ cord-006870-f5w6fw6q 3190 3 ventilation ventilation NN cord-006870-f5w6fw6q 3190 4 and and CC cord-006870-f5w6fw6q 3190 5 ICP ICP NNP cord-006870-f5w6fw6q 3190 6 monitoring monitoring NN cord-006870-f5w6fw6q 3190 7 were be VBD cord-006870-f5w6fw6q 3190 8 enrolled enrol VBN cord-006870-f5w6fw6q 3190 9 in in IN cord-006870-f5w6fw6q 3190 10 this this DT cord-006870-f5w6fw6q 3190 11 pilot pilot NN cord-006870-f5w6fw6q 3190 12 study study NN cord-006870-f5w6fw6q 3190 13 . . . cord-006870-f5w6fw6q 3191 1 An an DT cord-006870-f5w6fw6q 3191 2 esophageal esophageal JJ cord-006870-f5w6fw6q 3191 3 balloon balloon NN cord-006870-f5w6fw6q 3191 4 was be VBD cord-006870-f5w6fw6q 3191 5 inserted insert VBN cord-006870-f5w6fw6q 3191 6 to to TO cord-006870-f5w6fw6q 3191 7 measure measure VB cord-006870-f5w6fw6q 3191 8 their -PRON- PRP$ cord-006870-f5w6fw6q 3191 9 transpulmonary transpulmonary JJ cord-006870-f5w6fw6q 3191 10 pressure pressure NN cord-006870-f5w6fw6q 3191 11 ( ( -LRB- cord-006870-f5w6fw6q 3191 12 Ptp Ptp NNP cord-006870-f5w6fw6q 3191 13 ) ) -RRB- cord-006870-f5w6fw6q 3191 14 . . . cord-006870-f5w6fw6q 3192 1 Fluid fluid JJ cord-006870-f5w6fw6q 3192 2 responsiveness responsiveness NN cord-006870-f5w6fw6q 3192 3 was be VBD cord-006870-f5w6fw6q 3192 4 assessed assess VBN cord-006870-f5w6fw6q 3192 5 prior prior RB cord-006870-f5w6fw6q 3192 6 to to IN cord-006870-f5w6fw6q 3192 7 the the DT cord-006870-f5w6fw6q 3192 8 intervention intervention NN cord-006870-f5w6fw6q 3192 9 . . . cord-006870-f5w6fw6q 3193 1 Subjects subject NNS cord-006870-f5w6fw6q 3193 2 underwent undergo VBD cord-006870-f5w6fw6q 3193 3 a a DT cord-006870-f5w6fw6q 3193 4 step step NN cord-006870-f5w6fw6q 3193 5 - - HYPH cord-006870-f5w6fw6q 3193 6 wise wise JJ cord-006870-f5w6fw6q 3193 7 increase increase NN cord-006870-f5w6fw6q 3193 8 in in IN cord-006870-f5w6fw6q 3193 9 PEEP peep NN cord-006870-f5w6fw6q 3193 10 ( ( -LRB- cord-006870-f5w6fw6q 3193 11 increments increment NNS cord-006870-f5w6fw6q 3193 12 of of IN cord-006870-f5w6fw6q 3193 13 five five CD cord-006870-f5w6fw6q 3193 14 ) ) -RRB- cord-006870-f5w6fw6q 3193 15 from from IN cord-006870-f5w6fw6q 3193 16 5 5 CD cord-006870-f5w6fw6q 3193 17 to to TO cord-006870-f5w6fw6q 3193 18 15 15 CD cord-006870-f5w6fw6q 3193 19 cmH2O. cmH2O. NNP cord-006870-f5w6fw6q 3193 20 Airway Airway NNP cord-006870-f5w6fw6q 3193 21 pressure pressure NN cord-006870-f5w6fw6q 3193 22 , , , cord-006870-f5w6fw6q 3193 23 Ptp Ptp NNP cord-006870-f5w6fw6q 3193 24 and and CC cord-006870-f5w6fw6q 3193 25 ICP ICP NNP cord-006870-f5w6fw6q 3193 26 were be VBD cord-006870-f5w6fw6q 3193 27 measured measure VBN cord-006870-f5w6fw6q 3193 28 at at IN cord-006870-f5w6fw6q 3193 29 each each DT cord-006870-f5w6fw6q 3193 30 PEEP PEEP NNP cord-006870-f5w6fw6q 3193 31 interval interval NN cord-006870-f5w6fw6q 3193 32 . . . cord-006870-f5w6fw6q 3194 1 Of of IN cord-006870-f5w6fw6q 3194 2 the the DT cord-006870-f5w6fw6q 3194 3 planned planned JJ cord-006870-f5w6fw6q 3194 4 twenty twenty CD cord-006870-f5w6fw6q 3194 5 , , , cord-006870-f5w6fw6q 3194 6 three three CD cord-006870-f5w6fw6q 3194 7 patients patient NNS cord-006870-f5w6fw6q 3194 8 have have VBP cord-006870-f5w6fw6q 3194 9 been be VBN cord-006870-f5w6fw6q 3194 10 enrolled enrol VBN cord-006870-f5w6fw6q 3194 11 to to IN cord-006870-f5w6fw6q 3194 12 date date NN cord-006870-f5w6fw6q 3194 13 . . . cord-006870-f5w6fw6q 3195 1 Primary primary JJ cord-006870-f5w6fw6q 3195 2 diagnoses diagnosis NNS cord-006870-f5w6fw6q 3195 3 included include VBD cord-006870-f5w6fw6q 3195 4 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 3195 5 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3195 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3195 7 and and CC cord-006870-f5w6fw6q 3195 8 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 3195 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3195 10 with with IN cord-006870-f5w6fw6q 3195 11 a a DT cord-006870-f5w6fw6q 3195 12 median median JJ cord-006870-f5w6fw6q 3195 13 GCS GCS NNP cord-006870-f5w6fw6q 3195 14 of of IN cord-006870-f5w6fw6q 3195 15 7 7 CD cord-006870-f5w6fw6q 3195 16 . . . cord-006870-f5w6fw6q 3196 1 Patients patient NNS cord-006870-f5w6fw6q 3196 2 were be VBD cord-006870-f5w6fw6q 3196 3 ventilated ventilate VBN cord-006870-f5w6fw6q 3196 4 using use VBG cord-006870-f5w6fw6q 3196 5 either either DT cord-006870-f5w6fw6q 3196 6 volume volume NN cord-006870-f5w6fw6q 3196 7 control control NN cord-006870-f5w6fw6q 3196 8 or or CC cord-006870-f5w6fw6q 3196 9 pressure pressure NN cord-006870-f5w6fw6q 3196 10 support support NN cord-006870-f5w6fw6q 3196 11 ventilation ventilation NN cord-006870-f5w6fw6q 3196 12 ; ; : cord-006870-f5w6fw6q 3196 13 median median JJ cord-006870-f5w6fw6q 3196 14 FiO2 FiO2 NNS cord-006870-f5w6fw6q 3196 15 was be VBD cord-006870-f5w6fw6q 3196 16 0.35 0.35 CD cord-006870-f5w6fw6q 3196 17 . . . cord-006870-f5w6fw6q 3197 1 Two two CD cord-006870-f5w6fw6q 3197 2 patients patient NNS cord-006870-f5w6fw6q 3197 3 were be VBD cord-006870-f5w6fw6q 3197 4 on on IN cord-006870-f5w6fw6q 3197 5 vasopressors vasopressor NNS cord-006870-f5w6fw6q 3197 6 and and CC cord-006870-f5w6fw6q 3197 7 the the DT cord-006870-f5w6fw6q 3197 8 same same JJ cord-006870-f5w6fw6q 3197 9 two two CD cord-006870-f5w6fw6q 3197 10 patients patient NNS cord-006870-f5w6fw6q 3197 11 were be VBD cord-006870-f5w6fw6q 3197 12 determined determine VBN cord-006870-f5w6fw6q 3197 13 to to TO cord-006870-f5w6fw6q 3197 14 be be VB cord-006870-f5w6fw6q 3197 15 fluid fluid JJ cord-006870-f5w6fw6q 3197 16 responsive responsive JJ cord-006870-f5w6fw6q 3197 17 . . . cord-006870-f5w6fw6q 3198 1 At at IN cord-006870-f5w6fw6q 3198 2 baseline baseline NN cord-006870-f5w6fw6q 3198 3 ( ( -LRB- cord-006870-f5w6fw6q 3198 4 PEEP PEEP NNP cord-006870-f5w6fw6q 3198 5 5 5 CD cord-006870-f5w6fw6q 3198 6 ) ) -RRB- cord-006870-f5w6fw6q 3198 7 , , , cord-006870-f5w6fw6q 3198 8 mean mean VB cord-006870-f5w6fw6q 3198 9 ICP ICP NNP cord-006870-f5w6fw6q 3198 10 , , , cord-006870-f5w6fw6q 3198 11 CPP CPP NNP cord-006870-f5w6fw6q 3198 12 , , , cord-006870-f5w6fw6q 3198 13 and and CC cord-006870-f5w6fw6q 3198 14 Ptp Ptp NNP cord-006870-f5w6fw6q 3198 15 were be VBD cord-006870-f5w6fw6q 3198 16 6mmHg 6mmhg CD cord-006870-f5w6fw6q 3198 17 , , , cord-006870-f5w6fw6q 3198 18 85mmHg 85mmhg CD cord-006870-f5w6fw6q 3198 19 , , , cord-006870-f5w6fw6q 3198 20 and and CC cord-006870-f5w6fw6q 3198 21 -3.18cmH2O -3.18cmh2o ADD cord-006870-f5w6fw6q 3198 22 , , , cord-006870-f5w6fw6q 3198 23 respectively respectively RB cord-006870-f5w6fw6q 3198 24 . . . cord-006870-f5w6fw6q 3199 1 When when WRB cord-006870-f5w6fw6q 3199 2 PEEP PEEP NNP cord-006870-f5w6fw6q 3199 3 was be VBD cord-006870-f5w6fw6q 3199 4 increased increase VBN cord-006870-f5w6fw6q 3199 5 to to IN cord-006870-f5w6fw6q 3199 6 10 10 CD cord-006870-f5w6fw6q 3199 7 cmH2O cmH2O NNP cord-006870-f5w6fw6q 3199 8 , , , cord-006870-f5w6fw6q 3199 9 the the DT cord-006870-f5w6fw6q 3199 10 average average JJ cord-006870-f5w6fw6q 3199 11 change change NN cord-006870-f5w6fw6q 3199 12 from from IN cord-006870-f5w6fw6q 3199 13 baseline baseline NN cord-006870-f5w6fw6q 3199 14 in in IN cord-006870-f5w6fw6q 3199 15 ICP ICP NNP cord-006870-f5w6fw6q 3199 16 and and CC cord-006870-f5w6fw6q 3199 17 CPP CPP NNP cord-006870-f5w6fw6q 3199 18 was be VBD cord-006870-f5w6fw6q 3199 19 -3.7 -3.7 NN cord-006870-f5w6fw6q 3199 20 % % NN cord-006870-f5w6fw6q 3199 21 and and CC cord-006870-f5w6fw6q 3199 22 -2.2 -2.2 CD cord-006870-f5w6fw6q 3199 23 % % NN cord-006870-f5w6fw6q 3199 24 , , , cord-006870-f5w6fw6q 3199 25 respectively respectively RB cord-006870-f5w6fw6q 3199 26 . . . cord-006870-f5w6fw6q 3200 1 When when WRB cord-006870-f5w6fw6q 3200 2 increased increase VBN cord-006870-f5w6fw6q 3200 3 to to IN cord-006870-f5w6fw6q 3200 4 15 15 CD cord-006870-f5w6fw6q 3200 5 cmH2O cmh2o VB cord-006870-f5w6fw6q 3200 6 the the DT cord-006870-f5w6fw6q 3200 7 change change NN cord-006870-f5w6fw6q 3200 8 from from IN cord-006870-f5w6fw6q 3200 9 baseline baseline NN cord-006870-f5w6fw6q 3200 10 in in IN cord-006870-f5w6fw6q 3200 11 ICP ICP NNP cord-006870-f5w6fw6q 3200 12 and and CC cord-006870-f5w6fw6q 3200 13 CPP CPP NNP cord-006870-f5w6fw6q 3200 14 was be VBD cord-006870-f5w6fw6q 3200 15 3.0 3.0 CD cord-006870-f5w6fw6q 3200 16 % % NN cord-006870-f5w6fw6q 3200 17 and and CC cord-006870-f5w6fw6q 3200 18 0.5 0.5 CD cord-006870-f5w6fw6q 3200 19 % % NN cord-006870-f5w6fw6q 3200 20 . . . cord-006870-f5w6fw6q 3201 1 During during IN cord-006870-f5w6fw6q 3201 2 the the DT cord-006870-f5w6fw6q 3201 3 intervention intervention NN cord-006870-f5w6fw6q 3201 4 ICP ICP NNP cord-006870-f5w6fw6q 3201 5 did do VBD cord-006870-f5w6fw6q 3201 6 not not RB cord-006870-f5w6fw6q 3201 7 exceed exceed VB cord-006870-f5w6fw6q 3201 8 20 20 CD cord-006870-f5w6fw6q 3201 9 mmHg mmHg NNS cord-006870-f5w6fw6q 3201 10 , , , cord-006870-f5w6fw6q 3201 11 nor nor CC cord-006870-f5w6fw6q 3201 12 did do VBD cord-006870-f5w6fw6q 3201 13 any any DT cord-006870-f5w6fw6q 3201 14 patient patient JJ cord-006870-f5w6fw6q 3201 15 experience experience NN cord-006870-f5w6fw6q 3201 16 hypotension hypotension NN cord-006870-f5w6fw6q 3201 17 . . . cord-006870-f5w6fw6q 3202 1 Preliminary preliminary JJ cord-006870-f5w6fw6q 3202 2 data data NN cord-006870-f5w6fw6q 3202 3 suggests suggest VBZ cord-006870-f5w6fw6q 3202 4 that that IN cord-006870-f5w6fw6q 3202 5 intrathoracic intrathoracic JJ cord-006870-f5w6fw6q 3202 6 pressure pressure NN cord-006870-f5w6fw6q 3202 7 is be VBZ cord-006870-f5w6fw6q 3202 8 not not RB cord-006870-f5w6fw6q 3202 9 directly directly RB cord-006870-f5w6fw6q 3202 10 transmitted transmit VBN cord-006870-f5w6fw6q 3202 11 to to IN cord-006870-f5w6fw6q 3202 12 the the DT cord-006870-f5w6fw6q 3202 13 intracranial intracranial JJ cord-006870-f5w6fw6q 3202 14 compartment compartment NN cord-006870-f5w6fw6q 3202 15 . . . cord-006870-f5w6fw6q 3203 1 Continued continued JJ cord-006870-f5w6fw6q 3203 2 enrollment enrollment NN cord-006870-f5w6fw6q 3203 3 is be VBZ cord-006870-f5w6fw6q 3203 4 needed need VBN cord-006870-f5w6fw6q 3203 5 to to TO cord-006870-f5w6fw6q 3203 6 confirm confirm VB cord-006870-f5w6fw6q 3203 7 these these DT cord-006870-f5w6fw6q 3203 8 findings finding NNS cord-006870-f5w6fw6q 3203 9 . . . cord-006870-f5w6fw6q 3204 1 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3204 2 care care NN cord-006870-f5w6fw6q 3204 3 after after IN cord-006870-f5w6fw6q 3204 4 severe severe JJ cord-006870-f5w6fw6q 3204 5 traumatic traumatic JJ cord-006870-f5w6fw6q 3204 6 brain brain NN cord-006870-f5w6fw6q 3204 7 injury injury NN cord-006870-f5w6fw6q 3204 8 ( ( -LRB- cord-006870-f5w6fw6q 3204 9 sTBI stbi NN cord-006870-f5w6fw6q 3204 10 ) ) -RRB- cord-006870-f5w6fw6q 3204 11 is be VBZ cord-006870-f5w6fw6q 3204 12 focused focus VBN cord-006870-f5w6fw6q 3204 13 on on IN cord-006870-f5w6fw6q 3204 14 detecting detect VBG cord-006870-f5w6fw6q 3204 15 and and CC cord-006870-f5w6fw6q 3204 16 preventing prevent VBG cord-006870-f5w6fw6q 3204 17 secondary secondary JJ cord-006870-f5w6fw6q 3204 18 brain brain NN cord-006870-f5w6fw6q 3204 19 injuries injury NNS cord-006870-f5w6fw6q 3204 20 . . . cord-006870-f5w6fw6q 3205 1 In in IN cord-006870-f5w6fw6q 3205 2 addition addition NN cord-006870-f5w6fw6q 3205 3 to to IN cord-006870-f5w6fw6q 3205 4 intracranial intracranial JJ cord-006870-f5w6fw6q 3205 5 pressure pressure NN cord-006870-f5w6fw6q 3205 6 ( ( -LRB- cord-006870-f5w6fw6q 3205 7 ICP ICP NNP cord-006870-f5w6fw6q 3205 8 ) ) -RRB- cord-006870-f5w6fw6q 3205 9 , , , cord-006870-f5w6fw6q 3205 10 measures measure NNS cord-006870-f5w6fw6q 3205 11 of of IN cord-006870-f5w6fw6q 3205 12 brain brain NN cord-006870-f5w6fw6q 3205 13 tissue tissue NN cord-006870-f5w6fw6q 3205 14 oxygen oxygen NN cord-006870-f5w6fw6q 3205 15 ( ( -LRB- cord-006870-f5w6fw6q 3205 16 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3205 17 ) ) -RRB- cord-006870-f5w6fw6q 3205 18 , , , cord-006870-f5w6fw6q 3205 19 regional regional JJ cord-006870-f5w6fw6q 3205 20 cerebral cerebral JJ cord-006870-f5w6fw6q 3205 21 blood blood NN cord-006870-f5w6fw6q 3205 22 flow flow NN cord-006870-f5w6fw6q 3205 23 ( ( -LRB- cord-006870-f5w6fw6q 3205 24 rCBF rcbf NN cord-006870-f5w6fw6q 3205 25 ) ) -RRB- cord-006870-f5w6fw6q 3205 26 , , , cord-006870-f5w6fw6q 3205 27 and and CC cord-006870-f5w6fw6q 3205 28 electrocorticography electrocorticography NNP cord-006870-f5w6fw6q 3205 29 ( ( -LRB- cord-006870-f5w6fw6q 3205 30 dEEG deeg JJ cord-006870-f5w6fw6q 3205 31 ) ) -RRB- cord-006870-f5w6fw6q 3205 32 may may MD cord-006870-f5w6fw6q 3205 33 provide provide VB cord-006870-f5w6fw6q 3205 34 critical critical JJ cord-006870-f5w6fw6q 3205 35 clinical clinical JJ cord-006870-f5w6fw6q 3205 36 data datum NNS cord-006870-f5w6fw6q 3205 37 . . . cord-006870-f5w6fw6q 3206 1 Few few JJ cord-006870-f5w6fw6q 3206 2 studies study NNS cord-006870-f5w6fw6q 3206 3 have have VBP cord-006870-f5w6fw6q 3206 4 assessed assess VBN cord-006870-f5w6fw6q 3206 5 the the DT cord-006870-f5w6fw6q 3206 6 safety safety NN cord-006870-f5w6fw6q 3206 7 of of IN cord-006870-f5w6fw6q 3206 8 such such PDT cord-006870-f5w6fw6q 3206 9 an an DT cord-006870-f5w6fw6q 3206 10 approach approach NN cord-006870-f5w6fw6q 3206 11 and and CC cord-006870-f5w6fw6q 3206 12 the the DT cord-006870-f5w6fw6q 3206 13 reliability reliability NN cord-006870-f5w6fw6q 3206 14 of of IN cord-006870-f5w6fw6q 3206 15 data datum NNS cord-006870-f5w6fw6q 3206 16 that that WDT cord-006870-f5w6fw6q 3206 17 is be VBZ cord-006870-f5w6fw6q 3206 18 gathered gather VBN cord-006870-f5w6fw6q 3206 19 . . . cord-006870-f5w6fw6q 3207 1 We -PRON- PRP cord-006870-f5w6fw6q 3207 2 describe describe VBP cord-006870-f5w6fw6q 3207 3 here here RB cord-006870-f5w6fw6q 3207 4 the the DT cord-006870-f5w6fw6q 3207 5 placement placement NN cord-006870-f5w6fw6q 3207 6 , , , cord-006870-f5w6fw6q 3207 7 complications complication NNS cord-006870-f5w6fw6q 3207 8 , , , cord-006870-f5w6fw6q 3207 9 and and CC cord-006870-f5w6fw6q 3207 10 reliability reliability NN cord-006870-f5w6fw6q 3207 11 of of IN cord-006870-f5w6fw6q 3207 12 multimodality multimodality NN cord-006870-f5w6fw6q 3207 13 monitoring monitoring NN cord-006870-f5w6fw6q 3207 14 ( ( -LRB- cord-006870-f5w6fw6q 3207 15 MMM MMM NNP cord-006870-f5w6fw6q 3207 16 ) ) -RRB- cord-006870-f5w6fw6q 3207 17 data datum NNS cord-006870-f5w6fw6q 3207 18 from from IN cord-006870-f5w6fw6q 3207 19 a a DT cord-006870-f5w6fw6q 3207 20 novel novel NN cord-006870-f5w6fw6q 3207 21 , , , cord-006870-f5w6fw6q 3207 22 single single JJ cord-006870-f5w6fw6q 3207 23 burr burr NNP cord-006870-f5w6fw6q 3207 24 hole hole NN cord-006870-f5w6fw6q 3207 25 approach approach NN cord-006870-f5w6fw6q 3207 26 using use VBG cord-006870-f5w6fw6q 3207 27 a a DT cord-006870-f5w6fw6q 3207 28 four four CD cord-006870-f5w6fw6q 3207 29 - - HYPH cord-006870-f5w6fw6q 3207 30 lumen lumen NN cord-006870-f5w6fw6q 3207 31 bolt bolt NN cord-006870-f5w6fw6q 3207 32 at at IN cord-006870-f5w6fw6q 3207 33 our -PRON- PRP$ cord-006870-f5w6fw6q 3207 34 institution institution NN cord-006870-f5w6fw6q 3207 35 . . . cord-006870-f5w6fw6q 3208 1 We -PRON- PRP cord-006870-f5w6fw6q 3208 2 included include VBD cord-006870-f5w6fw6q 3208 3 consecutive consecutive JJ cord-006870-f5w6fw6q 3208 4 adult adult NN cord-006870-f5w6fw6q 3208 5 sTBI stbi JJ cord-006870-f5w6fw6q 3208 6 patients patient NNS cord-006870-f5w6fw6q 3208 7 admitted admit VBD cord-006870-f5w6fw6q 3208 8 to to IN cord-006870-f5w6fw6q 3208 9 the the DT cord-006870-f5w6fw6q 3208 10 Neuroscience Neuroscience NNP cord-006870-f5w6fw6q 3208 11 Intensive Intensive NNP cord-006870-f5w6fw6q 3208 12 Care Care NNP cord-006870-f5w6fw6q 3208 13 Unit Unit NNP cord-006870-f5w6fw6q 3208 14 at at IN cord-006870-f5w6fw6q 3208 15 the the DT cord-006870-f5w6fw6q 3208 16 University University NNP cord-006870-f5w6fw6q 3208 17 of of IN cord-006870-f5w6fw6q 3208 18 Cincinnati Cincinnati NNP cord-006870-f5w6fw6q 3208 19 from from IN cord-006870-f5w6fw6q 3208 20 April April NNP cord-006870-f5w6fw6q 3208 21 2015 2015 CD cord-006870-f5w6fw6q 3208 22 to to IN cord-006870-f5w6fw6q 3208 23 March March NNP cord-006870-f5w6fw6q 3208 24 2017 2017 CD cord-006870-f5w6fw6q 3208 25 who who WP cord-006870-f5w6fw6q 3208 26 underwent undergo VBD cord-006870-f5w6fw6q 3208 27 MMM MMM NNP cord-006870-f5w6fw6q 3208 28 as as IN cord-006870-f5w6fw6q 3208 29 part part NN cord-006870-f5w6fw6q 3208 30 of of IN cord-006870-f5w6fw6q 3208 31 standard standard JJ cord-006870-f5w6fw6q 3208 32 clinical clinical JJ cord-006870-f5w6fw6q 3208 33 management management NN cord-006870-f5w6fw6q 3208 34 per per IN cord-006870-f5w6fw6q 3208 35 institutional institutional JJ cord-006870-f5w6fw6q 3208 36 protocol protocol NN cord-006870-f5w6fw6q 3208 37 . . . cord-006870-f5w6fw6q 3209 1 Data datum NNS cord-006870-f5w6fw6q 3209 2 was be VBD cord-006870-f5w6fw6q 3209 3 obtained obtain VBN cord-006870-f5w6fw6q 3209 4 regarding regard VBG cord-006870-f5w6fw6q 3209 5 device device NN cord-006870-f5w6fw6q 3209 6 placement placement NN cord-006870-f5w6fw6q 3209 7 and and CC cord-006870-f5w6fw6q 3209 8 complications complication NNS cord-006870-f5w6fw6q 3209 9 . . . cord-006870-f5w6fw6q 3210 1 All all DT cord-006870-f5w6fw6q 3210 2 data datum NNS cord-006870-f5w6fw6q 3210 3 was be VBD cord-006870-f5w6fw6q 3210 4 visually visually RB cord-006870-f5w6fw6q 3210 5 inspected inspect VBN cord-006870-f5w6fw6q 3210 6 for for IN cord-006870-f5w6fw6q 3210 7 errors error NNS cord-006870-f5w6fw6q 3210 8 and and CC cord-006870-f5w6fw6q 3210 9 gaps gap NNS cord-006870-f5w6fw6q 3210 10 in in IN cord-006870-f5w6fw6q 3210 11 data datum NNS cord-006870-f5w6fw6q 3210 12 . . . cord-006870-f5w6fw6q 3211 1 40 40 CD cord-006870-f5w6fw6q 3211 2 patients patient NNS cord-006870-f5w6fw6q 3211 3 were be VBD cord-006870-f5w6fw6q 3211 4 included include VBN cord-006870-f5w6fw6q 3211 5 . . . cord-006870-f5w6fw6q 3212 1 The the DT cord-006870-f5w6fw6q 3212 2 mean mean JJ cord-006870-f5w6fw6q 3212 3 age age NN cord-006870-f5w6fw6q 3212 4 was be VBD cord-006870-f5w6fw6q 3212 5 43+/-17 43+/-17 CD cord-006870-f5w6fw6q 3212 6 and and CC cord-006870-f5w6fw6q 3212 7 85 85 CD cord-006870-f5w6fw6q 3212 8 % % NN cord-006870-f5w6fw6q 3212 9 were be VBD cord-006870-f5w6fw6q 3212 10 men man NNS cord-006870-f5w6fw6q 3212 11 . . . cord-006870-f5w6fw6q 3213 1 Bolts bolt NNS cord-006870-f5w6fw6q 3213 2 were be VBD cord-006870-f5w6fw6q 3213 3 placed place VBN cord-006870-f5w6fw6q 3213 4 a a DT cord-006870-f5w6fw6q 3213 5 median median NN cord-006870-f5w6fw6q 3213 6 of of IN cord-006870-f5w6fw6q 3213 7 17.7 17.7 CD cord-006870-f5w6fw6q 3213 8 ( ( -LRB- cord-006870-f5w6fw6q 3213 9 IQR IQR NNP cord-006870-f5w6fw6q 3213 10 8.3 8.3 CD cord-006870-f5w6fw6q 3213 11 - - HYPH cord-006870-f5w6fw6q 3213 12 16.9 16.9 CD cord-006870-f5w6fw6q 3213 13 ) ) -RRB- cord-006870-f5w6fw6q 3213 14 hours hour NNS cord-006870-f5w6fw6q 3213 15 from from IN cord-006870-f5w6fw6q 3213 16 injury injury NN cord-006870-f5w6fw6q 3213 17 . . . cord-006870-f5w6fw6q 3214 1 No no DT cord-006870-f5w6fw6q 3214 2 clinically clinically RB cord-006870-f5w6fw6q 3214 3 significant significant JJ cord-006870-f5w6fw6q 3214 4 complications complication NNS cord-006870-f5w6fw6q 3214 5 occurred occur VBD cord-006870-f5w6fw6q 3214 6 , , , cord-006870-f5w6fw6q 3214 7 although although IN cord-006870-f5w6fw6q 3214 8 37.5 37.5 CD cord-006870-f5w6fw6q 3214 9 % % NN cord-006870-f5w6fw6q 3214 10 had have VBD cord-006870-f5w6fw6q 3214 11 minor minor JJ cord-006870-f5w6fw6q 3214 12 complications complication NNS cord-006870-f5w6fw6q 3214 13 ( ( -LRB- cord-006870-f5w6fw6q 3214 14 e.g. e.g. DT cord-006870-f5w6fw6q 3214 15 small small JJ cord-006870-f5w6fw6q 3214 16 tract tract NN cord-006870-f5w6fw6q 3214 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3214 18 or or CC cord-006870-f5w6fw6q 3214 19 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 3214 20 ) ) -RRB- cord-006870-f5w6fw6q 3214 21 . . . cord-006870-f5w6fw6q 3215 1 Suboptimal suboptimal JJ cord-006870-f5w6fw6q 3215 2 placement placement NN cord-006870-f5w6fw6q 3215 3 of of IN cord-006870-f5w6fw6q 3215 4 probes probe NNS cord-006870-f5w6fw6q 3215 5 was be VBD cord-006870-f5w6fw6q 3215 6 noted note VBN cord-006870-f5w6fw6q 3215 7 in in IN cord-006870-f5w6fw6q 3215 8 13 13 CD cord-006870-f5w6fw6q 3215 9 % % NN cord-006870-f5w6fw6q 3215 10 . . . cord-006870-f5w6fw6q 3216 1 We -PRON- PRP cord-006870-f5w6fw6q 3216 2 monitored monitor VBD cord-006870-f5w6fw6q 3216 3 patients patient NNS cord-006870-f5w6fw6q 3216 4 a a DT cord-006870-f5w6fw6q 3216 5 median median JJ cord-006870-f5w6fw6q 3216 6 103.5 103.5 CD cord-006870-f5w6fw6q 3216 7 ( ( -LRB- cord-006870-f5w6fw6q 3216 8 IQR IQR NNP cord-006870-f5w6fw6q 3216 9 48.8 48.8 CD cord-006870-f5w6fw6q 3216 10 - - HYPH cord-006870-f5w6fw6q 3216 11 133.6 133.6 CD cord-006870-f5w6fw6q 3216 12 ) ) -RRB- cord-006870-f5w6fw6q 3216 13 hours hour NNS cord-006870-f5w6fw6q 3216 14 . . . cord-006870-f5w6fw6q 3217 1 ICP ICP NNP cord-006870-f5w6fw6q 3217 2 data datum NNS cord-006870-f5w6fw6q 3217 3 was be VBD cord-006870-f5w6fw6q 3217 4 the the DT cord-006870-f5w6fw6q 3217 5 most most RBS cord-006870-f5w6fw6q 3217 6 reliable reliable JJ cord-006870-f5w6fw6q 3217 7 , , , cord-006870-f5w6fw6q 3217 8 with with IN cord-006870-f5w6fw6q 3217 9 data datum NNS cord-006870-f5w6fw6q 3217 10 available available JJ cord-006870-f5w6fw6q 3217 11 94.8 94.8 CD cord-006870-f5w6fw6q 3217 12 % % NN cord-006870-f5w6fw6q 3217 13 of of IN cord-006870-f5w6fw6q 3217 14 the the DT cord-006870-f5w6fw6q 3217 15 total total JJ cord-006870-f5w6fw6q 3217 16 monitoring monitoring NN cord-006870-f5w6fw6q 3217 17 time time NN cord-006870-f5w6fw6q 3217 18 and and CC cord-006870-f5w6fw6q 3217 19 only only RB cord-006870-f5w6fw6q 3217 20 1.2 1.2 CD cord-006870-f5w6fw6q 3217 21 % % NN cord-006870-f5w6fw6q 3217 22 error error NN cord-006870-f5w6fw6q 3217 23 time time NN cord-006870-f5w6fw6q 3217 24 . . . cord-006870-f5w6fw6q 3218 1 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3218 2 and and CC cord-006870-f5w6fw6q 3218 3 dEEG deeg JJ cord-006870-f5w6fw6q 3218 4 data datum NNS cord-006870-f5w6fw6q 3218 5 were be VBD cord-006870-f5w6fw6q 3218 6 reliable reliable JJ cord-006870-f5w6fw6q 3218 7 for for IN cord-006870-f5w6fw6q 3218 8 > > XX cord-006870-f5w6fw6q 3218 9 90 90 CD cord-006870-f5w6fw6q 3218 10 % % NN cord-006870-f5w6fw6q 3218 11 of of IN cord-006870-f5w6fw6q 3218 12 total total JJ cord-006870-f5w6fw6q 3218 13 monitoring monitoring NN cord-006870-f5w6fw6q 3218 14 time time NN cord-006870-f5w6fw6q 3218 15 with with IN cord-006870-f5w6fw6q 3218 16 < < XX cord-006870-f5w6fw6q 3218 17 2 2 CD cord-006870-f5w6fw6q 3218 18 % % NN cord-006870-f5w6fw6q 3218 19 error error NN cord-006870-f5w6fw6q 3218 20 time time NN cord-006870-f5w6fw6q 3218 21 . . . cord-006870-f5w6fw6q 3219 1 rCBF rCBF NNP cord-006870-f5w6fw6q 3219 2 provided provide VBD cord-006870-f5w6fw6q 3219 3 data datum NNS cord-006870-f5w6fw6q 3219 4 for for IN cord-006870-f5w6fw6q 3219 5 77 77 CD cord-006870-f5w6fw6q 3219 6 % % NN cord-006870-f5w6fw6q 3219 7 of of IN cord-006870-f5w6fw6q 3219 8 total total JJ cord-006870-f5w6fw6q 3219 9 monitoring monitoring NN cord-006870-f5w6fw6q 3219 10 time time NN cord-006870-f5w6fw6q 3219 11 and and CC cord-006870-f5w6fw6q 3219 12 had have VBD cord-006870-f5w6fw6q 3219 13 17.9 17.9 CD cord-006870-f5w6fw6q 3219 14 % % NN cord-006870-f5w6fw6q 3219 15 error error NN cord-006870-f5w6fw6q 3219 16 time time NN cord-006870-f5w6fw6q 3219 17 . . . cord-006870-f5w6fw6q 3220 1 MMM MMM NNP cord-006870-f5w6fw6q 3220 2 in in IN cord-006870-f5w6fw6q 3220 3 sTBI stbi NN cord-006870-f5w6fw6q 3220 4 may may MD cord-006870-f5w6fw6q 3220 5 be be VB cord-006870-f5w6fw6q 3220 6 carried carry VBN cord-006870-f5w6fw6q 3220 7 out out RP cord-006870-f5w6fw6q 3220 8 via via IN cord-006870-f5w6fw6q 3220 9 a a DT cord-006870-f5w6fw6q 3220 10 single single JJ cord-006870-f5w6fw6q 3220 11 burr burr NN cord-006870-f5w6fw6q 3220 12 hole hole NN cord-006870-f5w6fw6q 3220 13 without without IN cord-006870-f5w6fw6q 3220 14 significant significant JJ cord-006870-f5w6fw6q 3220 15 clinical clinical JJ cord-006870-f5w6fw6q 3220 16 complications complication NNS cord-006870-f5w6fw6q 3220 17 and and CC cord-006870-f5w6fw6q 3220 18 reliably reliably RB cord-006870-f5w6fw6q 3220 19 yields yield VBZ cord-006870-f5w6fw6q 3220 20 continuous continuous JJ cord-006870-f5w6fw6q 3220 21 data datum NNS cord-006870-f5w6fw6q 3220 22 to to TO cord-006870-f5w6fw6q 3220 23 facilitate facilitate VB cord-006870-f5w6fw6q 3220 24 clinical clinical JJ cord-006870-f5w6fw6q 3220 25 decision decision NN cord-006870-f5w6fw6q 3220 26 making making NN cord-006870-f5w6fw6q 3220 27 . . . cord-006870-f5w6fw6q 3221 1 This this DT cord-006870-f5w6fw6q 3221 2 supports support VBZ cord-006870-f5w6fw6q 3221 3 the the DT cord-006870-f5w6fw6q 3221 4 feasibility feasibility NN cord-006870-f5w6fw6q 3221 5 of of IN cord-006870-f5w6fw6q 3221 6 our -PRON- PRP$ cord-006870-f5w6fw6q 3221 7 approach approach NN cord-006870-f5w6fw6q 3221 8 as as IN cord-006870-f5w6fw6q 3221 9 an an DT cord-006870-f5w6fw6q 3221 10 alternative alternative NN cord-006870-f5w6fw6q 3221 11 to to IN cord-006870-f5w6fw6q 3221 12 ICP ICP NNP cord-006870-f5w6fw6q 3221 13 monitoring monitor VBG cord-006870-f5w6fw6q 3221 14 alone alone RB cord-006870-f5w6fw6q 3221 15 . . . cord-006870-f5w6fw6q 3222 1 Intracranial intracranial JJ cord-006870-f5w6fw6q 3222 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3222 3 patients patient NNS cord-006870-f5w6fw6q 3222 4 with with IN cord-006870-f5w6fw6q 3222 5 non non JJ cord-006870-f5w6fw6q 3222 6 - - JJ cord-006870-f5w6fw6q 3222 7 compliant compliant JJ cord-006870-f5w6fw6q 3222 8 ventricles ventricle NNS cord-006870-f5w6fw6q 3222 9 may may MD cord-006870-f5w6fw6q 3222 10 have have VB cord-006870-f5w6fw6q 3222 11 high high JJ cord-006870-f5w6fw6q 3222 12 intracranial intracranial JJ cord-006870-f5w6fw6q 3222 13 pressure pressure NN cord-006870-f5w6fw6q 3222 14 ( ( -LRB- cord-006870-f5w6fw6q 3222 15 ICP ICP NNP cord-006870-f5w6fw6q 3222 16 ) ) -RRB- cord-006870-f5w6fw6q 3222 17 despite despite IN cord-006870-f5w6fw6q 3222 18 normal normal JJ cord-006870-f5w6fw6q 3222 19 ventricle ventricle NN cord-006870-f5w6fw6q 3222 20 size size NN cord-006870-f5w6fw6q 3222 21 . . . cord-006870-f5w6fw6q 3223 1 We -PRON- PRP cord-006870-f5w6fw6q 3223 2 aimed aim VBD cord-006870-f5w6fw6q 3223 3 to to TO cord-006870-f5w6fw6q 3223 4 assess assess VB cord-006870-f5w6fw6q 3223 5 the the DT cord-006870-f5w6fw6q 3223 6 incidence incidence NN cord-006870-f5w6fw6q 3223 7 of of IN cord-006870-f5w6fw6q 3223 8 elevated elevated JJ cord-006870-f5w6fw6q 3223 9 ICP ICP NNP cord-006870-f5w6fw6q 3223 10 among among IN cord-006870-f5w6fw6q 3223 11 those those DT cord-006870-f5w6fw6q 3223 12 with with IN cord-006870-f5w6fw6q 3223 13 no no DT cord-006870-f5w6fw6q 3223 14 radiographic radiographic JJ cord-006870-f5w6fw6q 3223 15 evidence evidence NN cord-006870-f5w6fw6q 3223 16 of of IN cord-006870-f5w6fw6q 3223 17 intracranial intracranial JJ cord-006870-f5w6fw6q 3223 18 hypertension hypertension NN cord-006870-f5w6fw6q 3223 19 . . . cord-006870-f5w6fw6q 3224 1 Prospectively prospectively RB cord-006870-f5w6fw6q 3224 2 enrolled enrol VBN cord-006870-f5w6fw6q 3224 3 primary primary JJ cord-006870-f5w6fw6q 3224 4 intracranial intracranial JJ cord-006870-f5w6fw6q 3224 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3224 6 patients patient NNS cord-006870-f5w6fw6q 3224 7 ( ( -LRB- cord-006870-f5w6fw6q 3224 8 SAH SAH NNP cord-006870-f5w6fw6q 3224 9 , , , cord-006870-f5w6fw6q 3224 10 SDH SDH NNP cord-006870-f5w6fw6q 3224 11 and and CC cord-006870-f5w6fw6q 3224 12 IPH IPH NNP cord-006870-f5w6fw6q 3224 13 ) ) -RRB- cord-006870-f5w6fw6q 3224 14 admitted admit VBD cord-006870-f5w6fw6q 3224 15 to to IN cord-006870-f5w6fw6q 3224 16 two two CD cord-006870-f5w6fw6q 3224 17 tertiary tertiary JJ cord-006870-f5w6fw6q 3224 18 - - HYPH cord-006870-f5w6fw6q 3224 19 care care NN cord-006870-f5w6fw6q 3224 20 centers center NNS cord-006870-f5w6fw6q 3224 21 between between IN cord-006870-f5w6fw6q 3224 22 4/2008 4/2008 CD cord-006870-f5w6fw6q 3224 23 - - HYPH cord-006870-f5w6fw6q 3224 24 5/2016 5/2016 CD cord-006870-f5w6fw6q 3224 25 were be VBD cord-006870-f5w6fw6q 3224 26 retrospectively retrospectively RB cord-006870-f5w6fw6q 3224 27 reviewed review VBN cord-006870-f5w6fw6q 3224 28 . . . cord-006870-f5w6fw6q 3225 1 Among among IN cord-006870-f5w6fw6q 3225 2 patients patient NNS cord-006870-f5w6fw6q 3225 3 with with IN cord-006870-f5w6fw6q 3225 4 external external JJ cord-006870-f5w6fw6q 3225 5 ventricular ventricular JJ cord-006870-f5w6fw6q 3225 6 drainage drainage NN cord-006870-f5w6fw6q 3225 7 ( ( -LRB- cord-006870-f5w6fw6q 3225 8 EVD EVD NNP cord-006870-f5w6fw6q 3225 9 ) ) -RRB- cord-006870-f5w6fw6q 3225 10 , , , cord-006870-f5w6fw6q 3225 11 admission admission NN cord-006870-f5w6fw6q 3225 12 head head NN cord-006870-f5w6fw6q 3225 13 CT CT NNP cord-006870-f5w6fw6q 3225 14 ( ( -LRB- cord-006870-f5w6fw6q 3225 15 HCT HCT NNP cord-006870-f5w6fw6q 3225 16 ) ) -RRB- cord-006870-f5w6fw6q 3225 17 scans scan VBZ cord-006870-f5w6fw6q 3225 18 within within IN cord-006870-f5w6fw6q 3225 19 72h 72h NNS cord-006870-f5w6fw6q 3225 20 prior prior RB cord-006870-f5w6fw6q 3225 21 to to IN cord-006870-f5w6fw6q 3225 22 EVD EVD NNP cord-006870-f5w6fw6q 3225 23 placement placement NN cord-006870-f5w6fw6q 3225 24 were be VBD cord-006870-f5w6fw6q 3225 25 reviewed review VBN cord-006870-f5w6fw6q 3225 26 for for IN cord-006870-f5w6fw6q 3225 27 evidence evidence NN cord-006870-f5w6fw6q 3225 28 of of IN cord-006870-f5w6fw6q 3225 29 elevated elevated JJ cord-006870-f5w6fw6q 3225 30 intracranial intracranial JJ cord-006870-f5w6fw6q 3225 31 pressure pressure NN cord-006870-f5w6fw6q 3225 32 ( ( -LRB- cord-006870-f5w6fw6q 3225 33 ICP ICP NNP cord-006870-f5w6fw6q 3225 34 ) ) -RRB- cord-006870-f5w6fw6q 3225 35 including include VBG cord-006870-f5w6fw6q 3225 36 : : : cord-006870-f5w6fw6q 3225 37 ventricle ventricle NN cord-006870-f5w6fw6q 3225 38 size size NN cord-006870-f5w6fw6q 3225 39 ( ( -LRB- cord-006870-f5w6fw6q 3225 40 bicaudate bicaudate NNP cord-006870-f5w6fw6q 3225 41 index index NN cord-006870-f5w6fw6q 3225 42 , , , cord-006870-f5w6fw6q 3225 43 temporal temporal JJ cord-006870-f5w6fw6q 3225 44 horn horn NN cord-006870-f5w6fw6q 3225 45 size size NN cord-006870-f5w6fw6q 3225 46 ) ) -RRB- cord-006870-f5w6fw6q 3225 47 , , , cord-006870-f5w6fw6q 3225 48 basal basal NN cord-006870-f5w6fw6q 3225 49 cistern cistern NN cord-006870-f5w6fw6q 3225 50 effacement effacement NN cord-006870-f5w6fw6q 3225 51 , , , cord-006870-f5w6fw6q 3225 52 midline midline JJ cord-006870-f5w6fw6q 3225 53 shift shift NN cord-006870-f5w6fw6q 3225 54 and and CC cord-006870-f5w6fw6q 3225 55 global global JJ cord-006870-f5w6fw6q 3225 56 cerebral cerebral JJ cord-006870-f5w6fw6q 3225 57 edema edema NN cord-006870-f5w6fw6q 3225 58 . . . cord-006870-f5w6fw6q 3226 1 When when WRB cord-006870-f5w6fw6q 3226 2 all all DT cord-006870-f5w6fw6q 3226 3 of of IN cord-006870-f5w6fw6q 3226 4 these these DT cord-006870-f5w6fw6q 3226 5 features feature NNS cord-006870-f5w6fw6q 3226 6 were be VBD cord-006870-f5w6fw6q 3226 7 absent absent JJ cord-006870-f5w6fw6q 3226 8 , , , cord-006870-f5w6fw6q 3226 9 patients patient NNS cord-006870-f5w6fw6q 3226 10 were be VBD cord-006870-f5w6fw6q 3226 11 classified classify VBN cord-006870-f5w6fw6q 3226 12 as as IN cord-006870-f5w6fw6q 3226 13 having have VBG cord-006870-f5w6fw6q 3226 14 normal normal JJ cord-006870-f5w6fw6q 3226 15 - - HYPH cord-006870-f5w6fw6q 3226 16 ICP ICP NNP cord-006870-f5w6fw6q 3226 17 HCT HCT NNP cord-006870-f5w6fw6q 3226 18 . . . cord-006870-f5w6fw6q 3227 1 The the DT cord-006870-f5w6fw6q 3227 2 incidence incidence NN cord-006870-f5w6fw6q 3227 3 of of IN cord-006870-f5w6fw6q 3227 4 elevated elevated JJ cord-006870-f5w6fw6q 3227 5 ICP ICP NNP cord-006870-f5w6fw6q 3227 6 ( ( -LRB- cord-006870-f5w6fw6q 3227 7 > > NFP cord-006870-f5w6fw6q 3227 8 20mmHg 20mmhg CD cord-006870-f5w6fw6q 3227 9 ) ) -RRB- cord-006870-f5w6fw6q 3227 10 at at IN cord-006870-f5w6fw6q 3227 11 the the DT cord-006870-f5w6fw6q 3227 12 time time NN cord-006870-f5w6fw6q 3227 13 of of IN cord-006870-f5w6fw6q 3227 14 EVD EVD NNP cord-006870-f5w6fw6q 3227 15 placement placement NN cord-006870-f5w6fw6q 3227 16 and and CC cord-006870-f5w6fw6q 3227 17 during during IN cord-006870-f5w6fw6q 3227 18 hospital hospital NN cord-006870-f5w6fw6q 3227 19 stay stay NN cord-006870-f5w6fw6q 3227 20 were be VBD cord-006870-f5w6fw6q 3227 21 recorded record VBN cord-006870-f5w6fw6q 3227 22 . . . cord-006870-f5w6fw6q 3228 1 Of of IN cord-006870-f5w6fw6q 3228 2 741 741 CD cord-006870-f5w6fw6q 3228 3 intracranial intracranial JJ cord-006870-f5w6fw6q 3228 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3228 5 patients patient NNS cord-006870-f5w6fw6q 3228 6 enrolled enrol VBD cord-006870-f5w6fw6q 3228 7 , , , cord-006870-f5w6fw6q 3228 8 253 253 CD cord-006870-f5w6fw6q 3228 9 ( ( -LRB- cord-006870-f5w6fw6q 3228 10 34 34 CD cord-006870-f5w6fw6q 3228 11 % % NN cord-006870-f5w6fw6q 3228 12 ) ) -RRB- cord-006870-f5w6fw6q 3228 13 had have VBD cord-006870-f5w6fw6q 3228 14 EVD EVD NNP cord-006870-f5w6fw6q 3228 15 . . . cord-006870-f5w6fw6q 3229 1 23/253 23/253 CD cord-006870-f5w6fw6q 3229 2 ( ( -LRB- cord-006870-f5w6fw6q 3229 3 9 9 CD cord-006870-f5w6fw6q 3229 4 % % NN cord-006870-f5w6fw6q 3229 5 ) ) -RRB- cord-006870-f5w6fw6q 3229 6 had have VBD cord-006870-f5w6fw6q 3229 7 a a DT cord-006870-f5w6fw6q 3229 8 normal normal JJ cord-006870-f5w6fw6q 3229 9 - - HYPH cord-006870-f5w6fw6q 3229 10 ICP ICP NNP cord-006870-f5w6fw6q 3229 11 HCT HCT NNP cord-006870-f5w6fw6q 3229 12 . . . cord-006870-f5w6fw6q 3230 1 Of of IN cord-006870-f5w6fw6q 3230 2 these these DT cord-006870-f5w6fw6q 3230 3 , , , cord-006870-f5w6fw6q 3230 4 11/23 11/23 CD cord-006870-f5w6fw6q 3230 5 ( ( -LRB- cord-006870-f5w6fw6q 3230 6 48 48 CD cord-006870-f5w6fw6q 3230 7 % % NN cord-006870-f5w6fw6q 3230 8 ) ) -RRB- cord-006870-f5w6fw6q 3230 9 had have VBD cord-006870-f5w6fw6q 3230 10 elevated elevate VBN cord-006870-f5w6fw6q 3230 11 opening opening NN cord-006870-f5w6fw6q 3230 12 pressure pressure NN cord-006870-f5w6fw6q 3230 13 at at IN cord-006870-f5w6fw6q 3230 14 the the DT cord-006870-f5w6fw6q 3230 15 time time NN cord-006870-f5w6fw6q 3230 16 of of IN cord-006870-f5w6fw6q 3230 17 EVD EVD NNP cord-006870-f5w6fw6q 3230 18 placement placement NN cord-006870-f5w6fw6q 3230 19 , , , cord-006870-f5w6fw6q 3230 20 and and CC cord-006870-f5w6fw6q 3230 21 13/23 13/23 CD cord-006870-f5w6fw6q 3230 22 ( ( -LRB- cord-006870-f5w6fw6q 3230 23 57 57 CD cord-006870-f5w6fw6q 3230 24 % % NN cord-006870-f5w6fw6q 3230 25 ) ) -RRB- cord-006870-f5w6fw6q 3230 26 had have VBD cord-006870-f5w6fw6q 3230 27 elevated elevate VBN cord-006870-f5w6fw6q 3230 28 ICP ICP NNP cord-006870-f5w6fw6q 3230 29 during during IN cord-006870-f5w6fw6q 3230 30 their -PRON- PRP$ cord-006870-f5w6fw6q 3230 31 hospital hospital NN cord-006870-f5w6fw6q 3230 32 stay stay NN cord-006870-f5w6fw6q 3230 33 . . . cord-006870-f5w6fw6q 3231 1 Among among IN cord-006870-f5w6fw6q 3231 2 normal normal JJ cord-006870-f5w6fw6q 3231 3 - - HYPH cord-006870-f5w6fw6q 3231 4 ICP ICP NNP cord-006870-f5w6fw6q 3231 5 HCT HCT NNP cord-006870-f5w6fw6q 3231 6 patients patient NNS cord-006870-f5w6fw6q 3231 7 with with IN cord-006870-f5w6fw6q 3231 8 ICP>20mmHg icp>20mmhg CD cord-006870-f5w6fw6q 3231 9 , , , cord-006870-f5w6fw6q 3231 10 92 92 CD cord-006870-f5w6fw6q 3231 11 % % NN cord-006870-f5w6fw6q 3231 12 had have VBD cord-006870-f5w6fw6q 3231 13 SAH SAH NNP cord-006870-f5w6fw6q 3231 14 , , , cord-006870-f5w6fw6q 3231 15 and and CC cord-006870-f5w6fw6q 3231 16 the the DT cord-006870-f5w6fw6q 3231 17 median median JJ cord-006870-f5w6fw6q 3231 18 GCS GCS NNP cord-006870-f5w6fw6q 3231 19 and and CC cord-006870-f5w6fw6q 3231 20 Hunt Hunt NNP cord-006870-f5w6fw6q 3231 21 - - HYPH cord-006870-f5w6fw6q 3231 22 Hess Hess NNP cord-006870-f5w6fw6q 3231 23 scores score NNS cord-006870-f5w6fw6q 3231 24 were be VBD cord-006870-f5w6fw6q 3231 25 14 14 CD cord-006870-f5w6fw6q 3232 1 ( ( -LRB- cord-006870-f5w6fw6q 3232 2 range range NNP cord-006870-f5w6fw6q 3232 3 3 3 CD cord-006870-f5w6fw6q 3232 4 - - SYM cord-006870-f5w6fw6q 3232 5 15 15 CD cord-006870-f5w6fw6q 3232 6 ) ) -RRB- cord-006870-f5w6fw6q 3232 7 and and CC cord-006870-f5w6fw6q 3232 8 3 3 CD cord-006870-f5w6fw6q 3233 1 ( ( -LRB- cord-006870-f5w6fw6q 3233 2 range range NNP cord-006870-f5w6fw6q 3233 3 2 2 CD cord-006870-f5w6fw6q 3233 4 - - SYM cord-006870-f5w6fw6q 3233 5 5 5 CD cord-006870-f5w6fw6q 3233 6 ) ) -RRB- cord-006870-f5w6fw6q 3233 7 . . . cord-006870-f5w6fw6q 3234 1 The the DT cord-006870-f5w6fw6q 3234 2 positive positive JJ cord-006870-f5w6fw6q 3234 3 and and CC cord-006870-f5w6fw6q 3234 4 negative negative JJ cord-006870-f5w6fw6q 3234 5 predictive predictive JJ cord-006870-f5w6fw6q 3234 6 values value NNS cord-006870-f5w6fw6q 3234 7 of of IN cord-006870-f5w6fw6q 3234 8 normal normal JJ cord-006870-f5w6fw6q 3234 9 - - HYPH cord-006870-f5w6fw6q 3234 10 re re NN cord-006870-f5w6fw6q 3234 11 52 52 CD cord-006870-f5w6fw6q 3234 12 % % NN cord-006870-f5w6fw6q 3234 13 62 62 CD cord-006870-f5w6fw6q 3234 14 % % NN cord-006870-f5w6fw6q 3234 15 , , , cord-006870-f5w6fw6q 3234 16 respectively respectively RB cord-006870-f5w6fw6q 3234 17 ( ( -LRB- cord-006870-f5w6fw6q 3234 18 AUC AUC NNP cord-006870-f5w6fw6q 3234 19 0.471 0.471 CD cord-006870-f5w6fw6q 3234 20 , , , cord-006870-f5w6fw6q 3234 21 P=0.648 P=0.648 NNP cord-006870-f5w6fw6q 3234 22 ) ) -RRB- cord-006870-f5w6fw6q 3235 1 The the DT cord-006870-f5w6fw6q 3235 2 only only JJ cord-006870-f5w6fw6q 3235 3 radiographic radiographic JJ cord-006870-f5w6fw6q 3235 4 feature feature NN cord-006870-f5w6fw6q 3235 5 that that WDT cord-006870-f5w6fw6q 3235 6 was be VBD cord-006870-f5w6fw6q 3235 7 associated associate VBN cord-006870-f5w6fw6q 3235 8 with with IN cord-006870-f5w6fw6q 3235 9 elevated elevated JJ cord-006870-f5w6fw6q 3235 10 ICP ICP NNP cord-006870-f5w6fw6q 3235 11 was be VBD cord-006870-f5w6fw6q 3235 12 global global JJ cord-006870-f5w6fw6q 3235 13 cerebral cerebral JJ cord-006870-f5w6fw6q 3235 14 edema edema NN cord-006870-f5w6fw6q 3235 15 ( ( -LRB- cord-006870-f5w6fw6q 3235 16 OR OR NNP cord-006870-f5w6fw6q 3235 17 5.4 5.4 CD cord-006870-f5w6fw6q 3235 18 , , , cord-006870-f5w6fw6q 3235 19 95 95 CD cord-006870-f5w6fw6q 3235 20 % % NN cord-006870-f5w6fw6q 3235 21 CI CI NNP cord-006870-f5w6fw6q 3235 22 3.5 3.5 CD cord-006870-f5w6fw6q 3235 23 - - HYPH cord-006870-f5w6fw6q 3235 24 8.4 8.4 CD cord-006870-f5w6fw6q 3235 25 , , , cord-006870-f5w6fw6q 3235 26 P<0.001 P<0.001 NNP cord-006870-f5w6fw6q 3235 27 ) ) -RRB- cord-006870-f5w6fw6q 3235 28 . . . cord-006870-f5w6fw6q 3236 1 Approximately approximately RB cord-006870-f5w6fw6q 3236 2 half half NN cord-006870-f5w6fw6q 3236 3 of of IN cord-006870-f5w6fw6q 3236 4 intracranial intracranial JJ cord-006870-f5w6fw6q 3236 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3236 6 patients patient NNS cord-006870-f5w6fw6q 3236 7 without without IN cord-006870-f5w6fw6q 3236 8 radiographic radiographic JJ cord-006870-f5w6fw6q 3236 9 features feature NNS cord-006870-f5w6fw6q 3236 10 of of IN cord-006870-f5w6fw6q 3236 11 elevated elevated JJ cord-006870-f5w6fw6q 3236 12 ICP ICP NNP cord-006870-f5w6fw6q 3236 13 had have VBD cord-006870-f5w6fw6q 3236 14 ICP>20mmHg ICP>20mmHg VBN cord-006870-f5w6fw6q 3236 15 at at IN cord-006870-f5w6fw6q 3236 16 the the DT cord-006870-f5w6fw6q 3236 17 time time NN cord-006870-f5w6fw6q 3236 18 of of IN cord-006870-f5w6fw6q 3236 19 EVD EVD NNP cord-006870-f5w6fw6q 3236 20 placement placement NN cord-006870-f5w6fw6q 3236 21 and and CC cord-006870-f5w6fw6q 3236 22 additional additional JJ cord-006870-f5w6fw6q 3236 23 patients patient NNS cord-006870-f5w6fw6q 3236 24 had have VBD cord-006870-f5w6fw6q 3236 25 elevated elevate VBN cord-006870-f5w6fw6q 3236 26 ICP ICP NNP cord-006870-f5w6fw6q 3236 27 during during IN cord-006870-f5w6fw6q 3236 28 their -PRON- PRP$ cord-006870-f5w6fw6q 3236 29 hospital hospital NN cord-006870-f5w6fw6q 3236 30 stay stay NN cord-006870-f5w6fw6q 3236 31 . . . cord-006870-f5w6fw6q 3237 1 Radiographic radiographic JJ cord-006870-f5w6fw6q 3237 2 findings finding NNS cord-006870-f5w6fw6q 3237 3 should should MD cord-006870-f5w6fw6q 3237 4 not not RB cord-006870-f5w6fw6q 3237 5 be be VB cord-006870-f5w6fw6q 3237 6 relied rely VBN cord-006870-f5w6fw6q 3237 7 upon upon IN cord-006870-f5w6fw6q 3237 8 to to TO cord-006870-f5w6fw6q 3237 9 exclude exclude VB cord-006870-f5w6fw6q 3237 10 the the DT cord-006870-f5w6fw6q 3237 11 possibility possibility NN cord-006870-f5w6fw6q 3237 12 of of IN cord-006870-f5w6fw6q 3237 13 elevated elevated JJ cord-006870-f5w6fw6q 3237 14 ICP ICP NNP cord-006870-f5w6fw6q 3237 15 . . . cord-006870-f5w6fw6q 3238 1 The the DT cord-006870-f5w6fw6q 3238 2 measurement measurement NN cord-006870-f5w6fw6q 3238 3 of of IN cord-006870-f5w6fw6q 3238 4 intracranial intracranial JJ cord-006870-f5w6fw6q 3238 5 pressure pressure NN cord-006870-f5w6fw6q 3238 6 ( ( -LRB- cord-006870-f5w6fw6q 3238 7 ICP ICP NNP cord-006870-f5w6fw6q 3238 8 ) ) -RRB- cord-006870-f5w6fw6q 3238 9 is be VBZ cord-006870-f5w6fw6q 3238 10 a a DT cord-006870-f5w6fw6q 3238 11 cornerstone cornerstone NN cord-006870-f5w6fw6q 3238 12 of of IN cord-006870-f5w6fw6q 3238 13 intensive intensive JJ cord-006870-f5w6fw6q 3238 14 care care NN cord-006870-f5w6fw6q 3238 15 management management NN cord-006870-f5w6fw6q 3238 16 following follow VBG cord-006870-f5w6fw6q 3238 17 severe severe JJ cord-006870-f5w6fw6q 3238 18 traumatic traumatic JJ cord-006870-f5w6fw6q 3238 19 brain brain NN cord-006870-f5w6fw6q 3238 20 injury injury NN cord-006870-f5w6fw6q 3238 21 ( ( -LRB- cord-006870-f5w6fw6q 3238 22 sTBI stbi NN cord-006870-f5w6fw6q 3238 23 ) ) -RRB- cord-006870-f5w6fw6q 3238 24 . . . cord-006870-f5w6fw6q 3239 1 It -PRON- PRP cord-006870-f5w6fw6q 3239 2 has have VBZ cord-006870-f5w6fw6q 3239 3 been be VBN cord-006870-f5w6fw6q 3239 4 only only RB cord-006870-f5w6fw6q 3239 5 recently recently RB cord-006870-f5w6fw6q 3239 6 that that IN cord-006870-f5w6fw6q 3239 7 the the DT cord-006870-f5w6fw6q 3239 8 time time NN cord-006870-f5w6fw6q 3239 9 integral integral JJ cord-006870-f5w6fw6q 3239 10 of of IN cord-006870-f5w6fw6q 3239 11 ICP ICP NNP cord-006870-f5w6fw6q 3239 12 has have VBZ cord-006870-f5w6fw6q 3239 13 been be VBN cord-006870-f5w6fw6q 3239 14 quantified quantify VBN cord-006870-f5w6fw6q 3239 15 in in IN cord-006870-f5w6fw6q 3239 16 relation relation NN cord-006870-f5w6fw6q 3239 17 to to IN cord-006870-f5w6fw6q 3239 18 outcome outcome NN cord-006870-f5w6fw6q 3239 19 ; ; : cord-006870-f5w6fw6q 3239 20 the the DT cord-006870-f5w6fw6q 3239 21 time time NN cord-006870-f5w6fw6q 3239 22 integral integral JJ cord-006870-f5w6fw6q 3239 23 of of IN cord-006870-f5w6fw6q 3239 24 brain brain NN cord-006870-f5w6fw6q 3239 25 tissue tissue NN cord-006870-f5w6fw6q 3239 26 oxygen oxygen NN cord-006870-f5w6fw6q 3239 27 ( ( -LRB- cord-006870-f5w6fw6q 3239 28 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3239 29 ) ) -RRB- cord-006870-f5w6fw6q 3239 30 has have VBZ cord-006870-f5w6fw6q 3239 31 not not RB cord-006870-f5w6fw6q 3239 32 been be VBN cord-006870-f5w6fw6q 3239 33 studied study VBN cord-006870-f5w6fw6q 3239 34 . . . cord-006870-f5w6fw6q 3240 1 We -PRON- PRP cord-006870-f5w6fw6q 3240 2 gathered gather VBD cord-006870-f5w6fw6q 3240 3 time time NN cord-006870-f5w6fw6q 3240 4 - - HYPH cord-006870-f5w6fw6q 3240 5 locked lock VBN cord-006870-f5w6fw6q 3240 6 intracranial intracranial JJ cord-006870-f5w6fw6q 3240 7 monitoring monitoring NN cord-006870-f5w6fw6q 3240 8 data datum NNS cord-006870-f5w6fw6q 3240 9 on on IN cord-006870-f5w6fw6q 3240 10 s s PRP$ cord-006870-f5w6fw6q 3240 11 TBI TBI NNP cord-006870-f5w6fw6q 3240 12 patients patient NNS cord-006870-f5w6fw6q 3240 13 at at IN cord-006870-f5w6fw6q 3240 14 the the DT cord-006870-f5w6fw6q 3240 15 University University NNP cord-006870-f5w6fw6q 3240 16 of of IN cord-006870-f5w6fw6q 3240 17 Cincinnati Cincinnati NNP cord-006870-f5w6fw6q 3240 18 over over IN cord-006870-f5w6fw6q 3240 19 2 2 CD cord-006870-f5w6fw6q 3240 20 years year NNS cord-006870-f5w6fw6q 3240 21 . . . cord-006870-f5w6fw6q 3241 1 Clinical clinical JJ cord-006870-f5w6fw6q 3241 2 management management NN cord-006870-f5w6fw6q 3241 3 of of IN cord-006870-f5w6fw6q 3241 4 all all DT cord-006870-f5w6fw6q 3241 5 patients patient NNS cord-006870-f5w6fw6q 3241 6 followed follow VBD cord-006870-f5w6fw6q 3241 7 national national JJ cord-006870-f5w6fw6q 3241 8 standards standard NNS cord-006870-f5w6fw6q 3241 9 . . . cord-006870-f5w6fw6q 3242 1 Raumedic Raumedic NNP cord-006870-f5w6fw6q 3242 2 PTO PTO NNP cord-006870-f5w6fw6q 3242 3 probe probe NN cord-006870-f5w6fw6q 3242 4 was be VBD cord-006870-f5w6fw6q 3242 5 used use VBN cord-006870-f5w6fw6q 3242 6 to to TO cord-006870-f5w6fw6q 3242 7 measure measure VB cord-006870-f5w6fw6q 3242 8 ICP ICP NNP cord-006870-f5w6fw6q 3242 9 and and CC cord-006870-f5w6fw6q 3242 10 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3242 11 ; ; : cord-006870-f5w6fw6q 3242 12 accuracy accuracy NN cord-006870-f5w6fw6q 3242 13 was be VBD cord-006870-f5w6fw6q 3242 14 verified verify VBN cord-006870-f5w6fw6q 3242 15 by by IN cord-006870-f5w6fw6q 3242 16 visual visual JJ cord-006870-f5w6fw6q 3242 17 inspection inspection NN cord-006870-f5w6fw6q 3242 18 with with IN cord-006870-f5w6fw6q 3242 19 automated automate VBN cord-006870-f5w6fw6q 3242 20 data datum NNS cord-006870-f5w6fw6q 3242 21 cleaning cleaning NN cord-006870-f5w6fw6q 3242 22 . . . cord-006870-f5w6fw6q 3243 1 Normalized normalized JJ cord-006870-f5w6fw6q 3243 2 data datum NNS cord-006870-f5w6fw6q 3243 3 was be VBD cord-006870-f5w6fw6q 3243 4 mapped map VBN cord-006870-f5w6fw6q 3243 5 based base VBN cord-006870-f5w6fw6q 3243 6 on on IN cord-006870-f5w6fw6q 3243 7 correlation correlation NN cord-006870-f5w6fw6q 3243 8 with with IN cord-006870-f5w6fw6q 3243 9 Glasgow Glasgow NNP cord-006870-f5w6fw6q 3243 10 Outcome Outcome NNP cord-006870-f5w6fw6q 3243 11 Scale scale NN cord-006870-f5w6fw6q 3243 12 scores score NNS cord-006870-f5w6fw6q 3243 13 at at IN cord-006870-f5w6fw6q 3243 14 3 3 CD cord-006870-f5w6fw6q 3243 15 - - SYM cord-006870-f5w6fw6q 3243 16 6 6 CD cord-006870-f5w6fw6q 3243 17 months month NNS cord-006870-f5w6fw6q 3243 18 . . . cord-006870-f5w6fw6q 3244 1 We -PRON- PRP cord-006870-f5w6fw6q 3244 2 studied study VBD cord-006870-f5w6fw6q 3244 3 43 43 CD cord-006870-f5w6fw6q 3244 4 patients patient NNS cord-006870-f5w6fw6q 3244 5 aged aged JJ cord-006870-f5w6fw6q 3244 6 42+/-18 42+/-18 CD cord-006870-f5w6fw6q 3244 7 years year NNS cord-006870-f5w6fw6q 3244 8 ( ( -LRB- cord-006870-f5w6fw6q 3244 9 mean+/-SD mean+/-sd NN cord-006870-f5w6fw6q 3244 10 ) ) -RRB- cord-006870-f5w6fw6q 3244 11 ; ; : cord-006870-f5w6fw6q 3244 12 84 84 CD cord-006870-f5w6fw6q 3244 13 % % NN cord-006870-f5w6fw6q 3244 14 were be VBD cord-006870-f5w6fw6q 3244 15 male male JJ cord-006870-f5w6fw6q 3244 16 . . . cord-006870-f5w6fw6q 3245 1 Initial initial JJ cord-006870-f5w6fw6q 3245 2 post post NN cord-006870-f5w6fw6q 3245 3 - - NN cord-006870-f5w6fw6q 3245 4 resuscitation resuscitation NN cord-006870-f5w6fw6q 3246 1 Glasgow Glasgow NNP cord-006870-f5w6fw6q 3246 2 Coma Coma NNP cord-006870-f5w6fw6q 3246 3 Scale Scale NNP cord-006870-f5w6fw6q 3246 4 score score NN cord-006870-f5w6fw6q 3246 5 was be VBD cord-006870-f5w6fw6q 3246 6 median median NN cord-006870-f5w6fw6q 3246 7 6 6 CD cord-006870-f5w6fw6q 3247 1 ( ( -LRB- cord-006870-f5w6fw6q 3247 2 interquartile interquartile JJ cord-006870-f5w6fw6q 3247 3 range range NN cord-006870-f5w6fw6q 3247 4 : : : cord-006870-f5w6fw6q 3247 5 4.5 4.5 CD cord-006870-f5w6fw6q 3247 6 - - SYM cord-006870-f5w6fw6q 3247 7 7 7 CD cord-006870-f5w6fw6q 3247 8 ) ) -RRB- cord-006870-f5w6fw6q 3247 9 . . . cord-006870-f5w6fw6q 3248 1 13/43 13/43 CD cord-006870-f5w6fw6q 3248 2 underwent undergo VBD cord-006870-f5w6fw6q 3248 3 craniectomy craniectomy NN cord-006870-f5w6fw6q 3248 4 prior prior RB cord-006870-f5w6fw6q 3248 5 to to IN cord-006870-f5w6fw6q 3248 6 monitoring monitoring NN cord-006870-f5w6fw6q 3248 7 . . . cord-006870-f5w6fw6q 3249 1 Among among IN cord-006870-f5w6fw6q 3249 2 those those DT cord-006870-f5w6fw6q 3249 3 with with IN cord-006870-f5w6fw6q 3249 4 good good JJ cord-006870-f5w6fw6q 3249 5 ( ( -LRB- cord-006870-f5w6fw6q 3249 6 GOS4 GOS4 NNP cord-006870-f5w6fw6q 3249 7 - - HYPH cord-006870-f5w6fw6q 3249 8 5 5 CD cord-006870-f5w6fw6q 3249 9 ) ) -RRB- cord-006870-f5w6fw6q 3249 10 and and CC cord-006870-f5w6fw6q 3249 11 poor poor JJ cord-006870-f5w6fw6q 3249 12 ( ( -LRB- cord-006870-f5w6fw6q 3249 13 GOS1 GOS1 NNP cord-006870-f5w6fw6q 3249 14 - - HYPH cord-006870-f5w6fw6q 3249 15 3 3 CD cord-006870-f5w6fw6q 3249 16 ) ) -RRB- cord-006870-f5w6fw6q 3249 17 outcome outcome NN cord-006870-f5w6fw6q 3249 18 , , , cord-006870-f5w6fw6q 3249 19 the the DT cord-006870-f5w6fw6q 3249 20 average average JJ cord-006870-f5w6fw6q 3249 21 ICP ICP NNP cord-006870-f5w6fw6q 3249 22 was be VBD cord-006870-f5w6fw6q 3249 23 13.2+/-5.6mmHg 13.2+/-5.6mmhg CD cord-006870-f5w6fw6q 3249 24 and and CC cord-006870-f5w6fw6q 3249 25 18.4+/-8.6mmHg 18.4+/-8.6mmhg CD cord-006870-f5w6fw6q 3249 26 ( ( -LRB- cord-006870-f5w6fw6q 3249 27 p=0.09 p=0.09 NN cord-006870-f5w6fw6q 3249 28 ) ) -RRB- cord-006870-f5w6fw6q 3249 29 ; ; : cord-006870-f5w6fw6q 3249 30 the the DT cord-006870-f5w6fw6q 3249 31 average average JJ cord-006870-f5w6fw6q 3249 32 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3249 33 was be VBD cord-006870-f5w6fw6q 3249 34 25.7+/-10.0mmHg 25.7+/-10.0mmhg CD cord-006870-f5w6fw6q 3249 35 and and CC cord-006870-f5w6fw6q 3249 36 31.1+/-21.5mmHg 31.1+/-21.5mmHg . cord-006870-f5w6fw6q 3249 37 ( ( -LRB- cord-006870-f5w6fw6q 3249 38 both both DT cord-006870-f5w6fw6q 3249 39 N.S. N.S. NNP cord-006870-f5w6fw6q 3249 40 ) ) -RRB- cord-006870-f5w6fw6q 3249 41 . . . cord-006870-f5w6fw6q 3250 1 The the DT cord-006870-f5w6fw6q 3250 2 correlation correlation NN cord-006870-f5w6fw6q 3250 3 with with IN cord-006870-f5w6fw6q 3250 4 outcome outcome NN cord-006870-f5w6fw6q 3250 5 was be VBD cord-006870-f5w6fw6q 3250 6 dependent dependent JJ cord-006870-f5w6fw6q 3250 7 on on IN cord-006870-f5w6fw6q 3250 8 both both CC cord-006870-f5w6fw6q 3250 9 ICP ICP NNP cord-006870-f5w6fw6q 3250 10 and and CC cord-006870-f5w6fw6q 3250 11 time time NN cord-006870-f5w6fw6q 3250 12 : : : cord-006870-f5w6fw6q 3250 13 an an DT cord-006870-f5w6fw6q 3250 14 ICP ICP NNP cord-006870-f5w6fw6q 3250 15 > > XX cord-006870-f5w6fw6q 3251 1 27mmHg 27mmhg CD cord-006870-f5w6fw6q 3251 2 for for IN cord-006870-f5w6fw6q 3251 3 > > $ cord-006870-f5w6fw6q 3251 4 5 5 CD cord-006870-f5w6fw6q 3251 5 minutes minute NNS cord-006870-f5w6fw6q 3251 6 was be VBD cord-006870-f5w6fw6q 3251 7 associated associate VBN cord-006870-f5w6fw6q 3251 8 with with IN cord-006870-f5w6fw6q 3251 9 poor poor JJ cord-006870-f5w6fw6q 3251 10 outcome outcome NN cord-006870-f5w6fw6q 3251 11 , , , cord-006870-f5w6fw6q 3251 12 whereas whereas IN cord-006870-f5w6fw6q 3251 13 an an DT cord-006870-f5w6fw6q 3251 14 ICP ICP NNP cord-006870-f5w6fw6q 3251 15 < < XX cord-006870-f5w6fw6q 3251 16 23mmHg 23mmhg CD cord-006870-f5w6fw6q 3251 17 was be VBD cord-006870-f5w6fw6q 3251 18 associated associate VBN cord-006870-f5w6fw6q 3251 19 with with IN cord-006870-f5w6fw6q 3251 20 poor poor JJ cord-006870-f5w6fw6q 3251 21 outcome outcome NN cord-006870-f5w6fw6q 3251 22 only only RB cord-006870-f5w6fw6q 3251 23 after after IN cord-006870-f5w6fw6q 3251 24 4 4 CD cord-006870-f5w6fw6q 3251 25 hours hour NNS cord-006870-f5w6fw6q 3251 26 . . . cord-006870-f5w6fw6q 3252 1 In in IN cord-006870-f5w6fw6q 3252 2 contrast contrast NN cord-006870-f5w6fw6q 3252 3 , , , cord-006870-f5w6fw6q 3252 4 the the DT cord-006870-f5w6fw6q 3252 5 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3252 6 level level NN cord-006870-f5w6fw6q 3252 7 , , , cord-006870-f5w6fw6q 3252 8 but but CC cord-006870-f5w6fw6q 3252 9 not not RB cord-006870-f5w6fw6q 3252 10 the the DT cord-006870-f5w6fw6q 3252 11 duration duration NN cord-006870-f5w6fw6q 3252 12 , , , cord-006870-f5w6fw6q 3252 13 correlated correlate VBN cord-006870-f5w6fw6q 3252 14 with with IN cord-006870-f5w6fw6q 3252 15 poor poor JJ cord-006870-f5w6fw6q 3252 16 outcome outcome NN cord-006870-f5w6fw6q 3252 17 in in IN cord-006870-f5w6fw6q 3252 18 those those DT cord-006870-f5w6fw6q 3252 19 without without IN cord-006870-f5w6fw6q 3252 20 craniectomy craniectomy NN cord-006870-f5w6fw6q 3252 21 at at IN cord-006870-f5w6fw6q 3252 22 a a DT cord-006870-f5w6fw6q 3252 23 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 3252 24 < < XX cord-006870-f5w6fw6q 3252 25 30mmHg 30mmhg CD cord-006870-f5w6fw6q 3252 26 , , , cord-006870-f5w6fw6q 3252 27 and and CC cord-006870-f5w6fw6q 3252 28 particularly particularly RB cord-006870-f5w6fw6q 3252 29 below below IN cord-006870-f5w6fw6q 3252 30 12mmHg 12mmhg CD cord-006870-f5w6fw6q 3252 31 . . . cord-006870-f5w6fw6q 3253 1 PbtO2 pbto2 CD cord-006870-f5w6fw6q 3253 2 burden burden NN cord-006870-f5w6fw6q 3253 3 was be VBD cord-006870-f5w6fw6q 3253 4 less less RBR cord-006870-f5w6fw6q 3253 5 reliable reliable JJ cord-006870-f5w6fw6q 3253 6 in in IN cord-006870-f5w6fw6q 3253 7 those those DT cord-006870-f5w6fw6q 3253 8 following follow VBG cord-006870-f5w6fw6q 3253 9 craniectomy craniectomy NN cord-006870-f5w6fw6q 3253 10 . . . cord-006870-f5w6fw6q 3254 1 We -PRON- PRP cord-006870-f5w6fw6q 3254 2 replicated replicate VBD cord-006870-f5w6fw6q 3254 3 the the DT cord-006870-f5w6fw6q 3254 4 effects effect NNS cord-006870-f5w6fw6q 3254 5 of of IN cord-006870-f5w6fw6q 3254 6 ICP ICP NNP cord-006870-f5w6fw6q 3254 7 / / SYM cord-006870-f5w6fw6q 3254 8 time time NN cord-006870-f5w6fw6q 3254 9 in in IN cord-006870-f5w6fw6q 3254 10 a a DT cord-006870-f5w6fw6q 3254 11 cohort cohort NN cord-006870-f5w6fw6q 3254 12 of of IN cord-006870-f5w6fw6q 3254 13 patients patient NNS cord-006870-f5w6fw6q 3254 14 with with IN cord-006870-f5w6fw6q 3254 15 severe severe JJ cord-006870-f5w6fw6q 3254 16 TBI TBI NNP cord-006870-f5w6fw6q 3254 17 , , , cord-006870-f5w6fw6q 3254 18 both both CC cord-006870-f5w6fw6q 3254 19 with with IN cord-006870-f5w6fw6q 3254 20 and and CC cord-006870-f5w6fw6q 3254 21 without without IN cord-006870-f5w6fw6q 3254 22 craniectomy craniectomy NN cord-006870-f5w6fw6q 3254 23 and and CC cord-006870-f5w6fw6q 3254 24 subsequently subsequently RB cord-006870-f5w6fw6q 3254 25 demonstrated demonstrate VBD cord-006870-f5w6fw6q 3254 26 the the DT cord-006870-f5w6fw6q 3254 27 burden burden NN cord-006870-f5w6fw6q 3254 28 of of IN cord-006870-f5w6fw6q 3254 29 brain brain NN cord-006870-f5w6fw6q 3254 30 tissue tissue NN cord-006870-f5w6fw6q 3254 31 hypoxia hypoxia NN cord-006870-f5w6fw6q 3254 32 in in IN cord-006870-f5w6fw6q 3254 33 those those DT cord-006870-f5w6fw6q 3254 34 without without IN cord-006870-f5w6fw6q 3254 35 craniectomy craniectomy NN cord-006870-f5w6fw6q 3254 36 . . . cord-006870-f5w6fw6q 3255 1 The the DT cord-006870-f5w6fw6q 3255 2 time time NN cord-006870-f5w6fw6q 3255 3 integral integral JJ cord-006870-f5w6fw6q 3255 4 of of IN cord-006870-f5w6fw6q 3255 5 multimodality multimodality NN cord-006870-f5w6fw6q 3255 6 monitoring monitoring NN cord-006870-f5w6fw6q 3255 7 data datum NNS cord-006870-f5w6fw6q 3255 8 may may MD cord-006870-f5w6fw6q 3255 9 provide provide VB cord-006870-f5w6fw6q 3255 10 more more RBR cord-006870-f5w6fw6q 3255 11 accurate accurate JJ cord-006870-f5w6fw6q 3255 12 measures measure NNS cord-006870-f5w6fw6q 3255 13 of of IN cord-006870-f5w6fw6q 3255 14 secondary secondary JJ cord-006870-f5w6fw6q 3255 15 insult insult NN cord-006870-f5w6fw6q 3255 16 burden burden NN cord-006870-f5w6fw6q 3255 17 with with IN cord-006870-f5w6fw6q 3255 18 implications implication NNS cord-006870-f5w6fw6q 3255 19 for for IN cord-006870-f5w6fw6q 3255 20 clinical clinical JJ cord-006870-f5w6fw6q 3255 21 care care NN cord-006870-f5w6fw6q 3255 22 and and CC cord-006870-f5w6fw6q 3255 23 prognosis prognosis NN cord-006870-f5w6fw6q 3255 24 . . . cord-006870-f5w6fw6q 3256 1 Neurologists neurologist NNS cord-006870-f5w6fw6q 3256 2 who who WP cord-006870-f5w6fw6q 3256 3 work work VBP cord-006870-f5w6fw6q 3256 4 in in IN cord-006870-f5w6fw6q 3256 5 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3256 6 care care NNP cord-006870-f5w6fw6q 3256 7 ( ( -LRB- cord-006870-f5w6fw6q 3256 8 NCC NCC NNP cord-006870-f5w6fw6q 3256 9 ) ) -RRB- cord-006870-f5w6fw6q 3256 10 as as IN cord-006870-f5w6fw6q 3256 11 neurointensivists neurointensivist NNS cord-006870-f5w6fw6q 3256 12 may may MD cord-006870-f5w6fw6q 3256 13 have have VB cord-006870-f5w6fw6q 3256 14 critical critical JJ cord-006870-f5w6fw6q 3256 15 care care NN cord-006870-f5w6fw6q 3256 16 ( ( -LRB- cord-006870-f5w6fw6q 3256 17 CC CC NNP cord-006870-f5w6fw6q 3256 18 ) ) -RRB- cord-006870-f5w6fw6q 3256 19 charges charge NNS cord-006870-f5w6fw6q 3256 20 rejected reject VBN cord-006870-f5w6fw6q 3256 21 for for IN cord-006870-f5w6fw6q 3256 22 payment payment NN cord-006870-f5w6fw6q 3256 23 unless unless IN cord-006870-f5w6fw6q 3256 24 they -PRON- PRP cord-006870-f5w6fw6q 3256 25 are be VBP cord-006870-f5w6fw6q 3256 26 classified classify VBN cord-006870-f5w6fw6q 3256 27 per per IN cord-006870-f5w6fw6q 3256 28 Centers Centers NNPS cord-006870-f5w6fw6q 3256 29 for for IN cord-006870-f5w6fw6q 3256 30 Medicare Medicare NNP cord-006870-f5w6fw6q 3257 1 Services service NNS cord-006870-f5w6fw6q 3257 2 ( ( -LRB- cord-006870-f5w6fw6q 3257 3 CMS CMS NNP cord-006870-f5w6fw6q 3257 4 ) ) -RRB- cord-006870-f5w6fw6q 3257 5 taxonomy taxonomy NN cord-006870-f5w6fw6q 3257 6 codes code NNS cord-006870-f5w6fw6q 3257 7 in in IN cord-006870-f5w6fw6q 3257 8 their -PRON- PRP$ cord-006870-f5w6fw6q 3257 9 systems system NNS cord-006870-f5w6fw6q 3257 10 as as IN cord-006870-f5w6fw6q 3257 11 critical critical JJ cord-006870-f5w6fw6q 3257 12 care care NN cord-006870-f5w6fw6q 3257 13 providers provider NNS cord-006870-f5w6fw6q 3257 14 . . . cord-006870-f5w6fw6q 3258 1 The the DT cord-006870-f5w6fw6q 3258 2 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3258 3 Care Care NNP cord-006870-f5w6fw6q 3258 4 Society Society NNP cord-006870-f5w6fw6q 3258 5 and and CC cord-006870-f5w6fw6q 3258 6 CMS CMS NNP cord-006870-f5w6fw6q 3258 7 created create VBD cord-006870-f5w6fw6q 3258 8 a a DT cord-006870-f5w6fw6q 3258 9 new new JJ cord-006870-f5w6fw6q 3258 10 NCC NCC NNP cord-006870-f5w6fw6q 3258 11 code code NN cord-006870-f5w6fw6q 3258 12 2084A2900X 2084a2900x CD cord-006870-f5w6fw6q 3258 13 to to TO cord-006870-f5w6fw6q 3258 14 fix fix VB cord-006870-f5w6fw6q 3258 15 this this DT cord-006870-f5w6fw6q 3258 16 issue issue NN cord-006870-f5w6fw6q 3258 17 . . . cord-006870-f5w6fw6q 3259 1 We -PRON- PRP cord-006870-f5w6fw6q 3259 2 polled poll VBD cord-006870-f5w6fw6q 3259 3 the the DT cord-006870-f5w6fw6q 3259 4 AAN AAN NNP cord-006870-f5w6fw6q 3259 5 CCEN CCEN NNP cord-006870-f5w6fw6q 3259 6 section section NN cord-006870-f5w6fw6q 3259 7 members member NNS cord-006870-f5w6fw6q 3259 8 for for IN cord-006870-f5w6fw6q 3259 9 awareness awareness NN cord-006870-f5w6fw6q 3259 10 of of IN cord-006870-f5w6fw6q 3259 11 this this DT cord-006870-f5w6fw6q 3259 12 problem problem NN cord-006870-f5w6fw6q 3259 13 . . . cord-006870-f5w6fw6q 3260 1 We -PRON- PRP cord-006870-f5w6fw6q 3260 2 conducted conduct VBD cord-006870-f5w6fw6q 3260 3 a a DT cord-006870-f5w6fw6q 3260 4 six six CD cord-006870-f5w6fw6q 3260 5 question question NN cord-006870-f5w6fw6q 3260 6 Google Google NNP cord-006870-f5w6fw6q 3260 7 Forms Forms NNP cord-006870-f5w6fw6q 3260 8 survey survey NN cord-006870-f5w6fw6q 3260 9 using use VBG cord-006870-f5w6fw6q 3260 10 the the DT cord-006870-f5w6fw6q 3260 11 AAN AAN NNP cord-006870-f5w6fw6q 3260 12 CCEN CCEN NNP cord-006870-f5w6fw6q 3260 13 Synapse Synapse NNP cord-006870-f5w6fw6q 3260 14 community community NN cord-006870-f5w6fw6q 3260 15 website website NN cord-006870-f5w6fw6q 3260 16 to to TO cord-006870-f5w6fw6q 3260 17 assess assess VB cord-006870-f5w6fw6q 3260 18 knowledge knowledge NN cord-006870-f5w6fw6q 3260 19 of of IN cord-006870-f5w6fw6q 3260 20 the the DT cord-006870-f5w6fw6q 3260 21 NCC NCC NNP cord-006870-f5w6fw6q 3260 22 taxonomy taxonomy NN cord-006870-f5w6fw6q 3260 23 code code NN cord-006870-f5w6fw6q 3260 24 : : : cord-006870-f5w6fw6q 3260 25 We -PRON- PRP cord-006870-f5w6fw6q 3260 26 received receive VBD cord-006870-f5w6fw6q 3260 27 20 20 CD cord-006870-f5w6fw6q 3260 28 anonymous anonymous JJ cord-006870-f5w6fw6q 3260 29 responses response NNS cord-006870-f5w6fw6q 3260 30 by by IN cord-006870-f5w6fw6q 3260 31 the the DT cord-006870-f5w6fw6q 3260 32 time time NN cord-006870-f5w6fw6q 3260 33 we -PRON- PRP cord-006870-f5w6fw6q 3260 34 closed close VBD cord-006870-f5w6fw6q 3260 35 the the DT cord-006870-f5w6fw6q 3260 36 poll poll NN cord-006870-f5w6fw6q 3260 37 on on IN cord-006870-f5w6fw6q 3260 38 7/13/17 7/13/17 CD cord-006870-f5w6fw6q 3260 39 . . . cord-006870-f5w6fw6q 3261 1 Question question NN cord-006870-f5w6fw6q 3261 2 ( ( -LRB- cord-006870-f5w6fw6q 3261 3 Q1 Q1 NNP cord-006870-f5w6fw6q 3261 4 ) ) -RRB- cord-006870-f5w6fw6q 3261 5 and and CC cord-006870-f5w6fw6q 3261 6 ( ( -LRB- cord-006870-f5w6fw6q 3261 7 Answers Answers NNPS cord-006870-f5w6fw6q 3261 8 , , , cord-006870-f5w6fw6q 3261 9 A1 A1 NNP cord-006870-f5w6fw6q 3261 10 ) ) -RRB- cord-006870-f5w6fw6q 3261 11 : : : cord-006870-f5w6fw6q 3261 12 Are be VBP cord-006870-f5w6fw6q 3261 13 you -PRON- PRP cord-006870-f5w6fw6q 3261 14 a a DT cord-006870-f5w6fw6q 3261 15 neurology neurology NN cord-006870-f5w6fw6q 3261 16 or or CC cord-006870-f5w6fw6q 3261 17 neurosurgery neurosurgery NNP cord-006870-f5w6fw6q 3261 18 back back RB cord-006870-f5w6fw6q 3261 19 grounded ground VBD cord-006870-f5w6fw6q 3261 20 intensivist intensivist NN cord-006870-f5w6fw6q 3261 21 who who WP cord-006870-f5w6fw6q 3261 22 does do VBZ cord-006870-f5w6fw6q 3261 23 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3261 24 care care NN cord-006870-f5w6fw6q 3261 25 at at IN cord-006870-f5w6fw6q 3261 26 your -PRON- PRP$ cord-006870-f5w6fw6q 3261 27 hospital hospital NN cord-006870-f5w6fw6q 3261 28 ? ? . cord-006870-f5w6fw6q 3262 1 Y Y NNP cord-006870-f5w6fw6q 3262 2 / / SYM cord-006870-f5w6fw6q 3262 3 N N NNP cord-006870-f5w6fw6q 3263 1 ( ( -LRB- cord-006870-f5w6fw6q 3263 2 yes yes UH cord-006870-f5w6fw6q 3263 3 / / SYM cord-006870-f5w6fw6q 3263 4 no no UH cord-006870-f5w6fw6q 3263 5 ) ) -RRB- cord-006870-f5w6fw6q 3263 6 . . . cord-006870-f5w6fw6q 3264 1 A1 a1 NN cord-006870-f5w6fw6q 3264 2 : : : cord-006870-f5w6fw6q 3265 1 95 95 CD cord-006870-f5w6fw6q 3265 2 % % NN cord-006870-f5w6fw6q 3265 3 reported report VBD cord-006870-f5w6fw6q 3265 4 being be VBG cord-006870-f5w6fw6q 3265 5 neurologists neurologist NNS cord-006870-f5w6fw6q 3265 6 . . . cord-006870-f5w6fw6q 3266 1 Q2 Q2 NNP cord-006870-f5w6fw6q 3266 2 : : : cord-006870-f5w6fw6q 3266 3 Were be VBD cord-006870-f5w6fw6q 3266 4 you -PRON- PRP cord-006870-f5w6fw6q 3266 5 aware aware JJ cord-006870-f5w6fw6q 3266 6 of of IN cord-006870-f5w6fw6q 3266 7 the the DT cord-006870-f5w6fw6q 3266 8 new new JJ cord-006870-f5w6fw6q 3266 9 CMS CMS NNP cord-006870-f5w6fw6q 3267 1 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3267 2 care care NN cord-006870-f5w6fw6q 3267 3 taxonomy taxonomy NN cord-006870-f5w6fw6q 3267 4 code code NN cord-006870-f5w6fw6q 3267 5 2084A2900X 2084a2900x CD cord-006870-f5w6fw6q 3267 6 ? ? . cord-006870-f5w6fw6q 3268 1 Y Y NNP cord-006870-f5w6fw6q 3268 2 / / SYM cord-006870-f5w6fw6q 3268 3 N N NNP cord-006870-f5w6fw6q 3268 4 A2 A2 NNP cord-006870-f5w6fw6q 3268 5 : : : cord-006870-f5w6fw6q 3268 6 55 55 CD cord-006870-f5w6fw6q 3268 7 % % NN cord-006870-f5w6fw6q 3268 8 were be VBD cord-006870-f5w6fw6q 3268 9 aware aware JJ cord-006870-f5w6fw6q 3268 10 of of IN cord-006870-f5w6fw6q 3268 11 the the DT cord-006870-f5w6fw6q 3268 12 taxonomy taxonomy NN cord-006870-f5w6fw6q 3268 13 code code NN cord-006870-f5w6fw6q 3268 14 . . . cord-006870-f5w6fw6q 3269 1 Q3 Q3 NNP cord-006870-f5w6fw6q 3269 2 : : : cord-006870-f5w6fw6q 3269 3 Are be VBP cord-006870-f5w6fw6q 3269 4 you -PRON- PRP cord-006870-f5w6fw6q 3269 5 aware aware JJ cord-006870-f5w6fw6q 3269 6 why why WRB cord-006870-f5w6fw6q 3269 7 the the DT cord-006870-f5w6fw6q 3269 8 NCC NCC NNP cord-006870-f5w6fw6q 3269 9 taxonomy taxonomy NN cord-006870-f5w6fw6q 3269 10 code code NN cord-006870-f5w6fw6q 3269 11 was be VBD cord-006870-f5w6fw6q 3269 12 created create VBN cord-006870-f5w6fw6q 3269 13 ? ? . cord-006870-f5w6fw6q 3270 1 Y Y NNP cord-006870-f5w6fw6q 3270 2 / / SYM cord-006870-f5w6fw6q 3270 3 N N NNP cord-006870-f5w6fw6q 3270 4 A3 A3 NNP cord-006870-f5w6fw6q 3270 5 : : : cord-006870-f5w6fw6q 3271 1 55 55 CD cord-006870-f5w6fw6q 3271 2 % % NN cord-006870-f5w6fw6q 3271 3 of of IN cord-006870-f5w6fw6q 3271 4 respondents respondent NNS cord-006870-f5w6fw6q 3271 5 were be VBD cord-006870-f5w6fw6q 3271 6 unaware unaware JJ cord-006870-f5w6fw6q 3271 7 why why WRB cord-006870-f5w6fw6q 3271 8 this this DT cord-006870-f5w6fw6q 3271 9 code code NN cord-006870-f5w6fw6q 3271 10 was be VBD cord-006870-f5w6fw6q 3271 11 created create VBN cord-006870-f5w6fw6q 3271 12 . . . cord-006870-f5w6fw6q 3272 1 Q4 Q4 NNP cord-006870-f5w6fw6q 3272 2 : : : cord-006870-f5w6fw6q 3273 1 What what WP cord-006870-f5w6fw6q 3273 2 is be VBZ cord-006870-f5w6fw6q 3273 3 your -PRON- PRP$ cord-006870-f5w6fw6q 3273 4 primary primary JJ cord-006870-f5w6fw6q 3273 5 department department NN cord-006870-f5w6fw6q 3273 6 for for IN cord-006870-f5w6fw6q 3273 7 revenue revenue NN cord-006870-f5w6fw6q 3273 8 collection collection NN cord-006870-f5w6fw6q 3273 9 ? ? . cord-006870-f5w6fw6q 3274 1 A4 A4 NNP cord-006870-f5w6fw6q 3274 2 : : : cord-006870-f5w6fw6q 3275 1 85 85 CD cord-006870-f5w6fw6q 3275 2 % % NN cord-006870-f5w6fw6q 3275 3 reported report VBD cord-006870-f5w6fw6q 3275 4 Neurology Neurology NNP cord-006870-f5w6fw6q 3275 5 , , , cord-006870-f5w6fw6q 3275 6 15 15 CD cord-006870-f5w6fw6q 3275 7 % % NN cord-006870-f5w6fw6q 3275 8 Neurosurgery Neurosurgery NNP cord-006870-f5w6fw6q 3275 9 , , , cord-006870-f5w6fw6q 3275 10 15 15 CD cord-006870-f5w6fw6q 3275 11 % % NN cord-006870-f5w6fw6q 3275 12 Critical critical JJ cord-006870-f5w6fw6q 3275 13 care care NN cord-006870-f5w6fw6q 3275 14 , , , cord-006870-f5w6fw6q 3275 15 and and CC cord-006870-f5w6fw6q 3275 16 15 15 CD cord-006870-f5w6fw6q 3275 17 % % NN cord-006870-f5w6fw6q 3275 18 blend blend NN cord-006870-f5w6fw6q 3275 19 . . . cord-006870-f5w6fw6q 3276 1 Q5 Q5 NNP cord-006870-f5w6fw6q 3277 1 : : : cord-006870-f5w6fw6q 3277 2 Are be VBP cord-006870-f5w6fw6q 3277 3 you -PRON- PRP cord-006870-f5w6fw6q 3277 4 aware aware JJ cord-006870-f5w6fw6q 3277 5 that that IN cord-006870-f5w6fw6q 3277 6 Medicare Medicare NNP cord-006870-f5w6fw6q 3277 7 can can MD cord-006870-f5w6fw6q 3277 8 reject reject VB cord-006870-f5w6fw6q 3277 9 critical critical JJ cord-006870-f5w6fw6q 3277 10 care care NN cord-006870-f5w6fw6q 3277 11 charges charge NNS cord-006870-f5w6fw6q 3277 12 ( ( -LRB- cord-006870-f5w6fw6q 3277 13 99291 99291 CD cord-006870-f5w6fw6q 3277 14 and and CC cord-006870-f5w6fw6q 3277 15 99292 99292 CD cord-006870-f5w6fw6q 3277 16 ) ) -RRB- cord-006870-f5w6fw6q 3277 17 can can MD cord-006870-f5w6fw6q 3277 18 be be VB cord-006870-f5w6fw6q 3277 19 rejected reject VBN cord-006870-f5w6fw6q 3277 20 unless unless IN cord-006870-f5w6fw6q 3277 21 you -PRON- PRP cord-006870-f5w6fw6q 3277 22 are be VBP cord-006870-f5w6fw6q 3277 23 listed list VBN cord-006870-f5w6fw6q 3277 24 as as IN cord-006870-f5w6fw6q 3277 25 a a DT cord-006870-f5w6fw6q 3277 26 CMS CMS NNP cord-006870-f5w6fw6q 3277 27 ' ' POS cord-006870-f5w6fw6q 3277 28 critical critical JJ cord-006870-f5w6fw6q 3277 29 care care NN cord-006870-f5w6fw6q 3277 30 provider provider NN cord-006870-f5w6fw6q 3277 31 ' ' '' cord-006870-f5w6fw6q 3277 32 or or CC cord-006870-f5w6fw6q 3277 33 as as IN cord-006870-f5w6fw6q 3277 34 a a DT cord-006870-f5w6fw6q 3277 35 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3277 36 care care NN cord-006870-f5w6fw6q 3277 37 provider provider NN cord-006870-f5w6fw6q 3277 38 ? ? . cord-006870-f5w6fw6q 3278 1 A5 A5 NNP cord-006870-f5w6fw6q 3278 2 : : : cord-006870-f5w6fw6q 3279 1 20 20 CD cord-006870-f5w6fw6q 3279 2 % % NN cord-006870-f5w6fw6q 3279 3 reported report VBD cord-006870-f5w6fw6q 3279 4 rejected reject VBN cord-006870-f5w6fw6q 3279 5 charges charge NNS cord-006870-f5w6fw6q 3279 6 at at IN cord-006870-f5w6fw6q 3279 7 their -PRON- PRP$ cord-006870-f5w6fw6q 3279 8 centers center NNS cord-006870-f5w6fw6q 3279 9 . . . cord-006870-f5w6fw6q 3280 1 Q6 Q6 NNP cord-006870-f5w6fw6q 3280 2 : : : cord-006870-f5w6fw6q 3280 3 Are be VBP cord-006870-f5w6fw6q 3280 4 you -PRON- PRP cord-006870-f5w6fw6q 3280 5 aware aware JJ cord-006870-f5w6fw6q 3280 6 of of IN cord-006870-f5w6fw6q 3280 7 rejection rejection NN cord-006870-f5w6fw6q 3280 8 of of IN cord-006870-f5w6fw6q 3280 9 critical critical JJ cord-006870-f5w6fw6q 3280 10 care care NN cord-006870-f5w6fw6q 3280 11 charges charge NNS cord-006870-f5w6fw6q 3280 12 happening happen VBG cord-006870-f5w6fw6q 3280 13 at at IN cord-006870-f5w6fw6q 3280 14 your -PRON- PRP$ cord-006870-f5w6fw6q 3280 15 own own JJ cord-006870-f5w6fw6q 3280 16 institution institution NN cord-006870-f5w6fw6q 3280 17 due due IN cord-006870-f5w6fw6q 3280 18 to to IN cord-006870-f5w6fw6q 3280 19 this this DT cord-006870-f5w6fw6q 3280 20 misclassification misclassification NN cord-006870-f5w6fw6q 3280 21 ? ? . cord-006870-f5w6fw6q 3281 1 Y Y NNP cord-006870-f5w6fw6q 3281 2 / / SYM cord-006870-f5w6fw6q 3281 3 N N NNP cord-006870-f5w6fw6q 3281 4 A6 A6 NNP cord-006870-f5w6fw6q 3281 5 : : : cord-006870-f5w6fw6q 3281 6 20 20 CD cord-006870-f5w6fw6q 3281 7 % % NN cord-006870-f5w6fw6q 3281 8 of of IN cord-006870-f5w6fw6q 3281 9 respondents respondent NNS cord-006870-f5w6fw6q 3281 10 reported report VBD cord-006870-f5w6fw6q 3281 11 rejected reject VBN cord-006870-f5w6fw6q 3281 12 charges charge NNS cord-006870-f5w6fw6q 3281 13 at at IN cord-006870-f5w6fw6q 3281 14 their -PRON- PRP$ cord-006870-f5w6fw6q 3281 15 center center NN cord-006870-f5w6fw6q 3281 16 . . . cord-006870-f5w6fw6q 3282 1 Although although IN cord-006870-f5w6fw6q 3282 2 limited limit VBN cord-006870-f5w6fw6q 3282 3 in in IN cord-006870-f5w6fw6q 3282 4 sample sample NN cord-006870-f5w6fw6q 3282 5 size size NN cord-006870-f5w6fw6q 3282 6 , , , cord-006870-f5w6fw6q 3282 7 this this DT cord-006870-f5w6fw6q 3282 8 survey survey NN cord-006870-f5w6fw6q 3282 9 revealed reveal VBD cord-006870-f5w6fw6q 3282 10 almost almost RB cord-006870-f5w6fw6q 3282 11 half half NN cord-006870-f5w6fw6q 3282 12 of of IN cord-006870-f5w6fw6q 3282 13 the the DT cord-006870-f5w6fw6q 3282 14 respondents respondent NNS cord-006870-f5w6fw6q 3282 15 were be VBD cord-006870-f5w6fw6q 3282 16 unaware unaware JJ cord-006870-f5w6fw6q 3282 17 of of IN cord-006870-f5w6fw6q 3282 18 the the DT cord-006870-f5w6fw6q 3282 19 NCC NCC NNP cord-006870-f5w6fw6q 3282 20 code code NN cord-006870-f5w6fw6q 3282 21 . . . cord-006870-f5w6fw6q 3283 1 We -PRON- PRP cord-006870-f5w6fw6q 3283 2 believe believe VBP cord-006870-f5w6fw6q 3283 3 a a DT cord-006870-f5w6fw6q 3283 4 larger large JJR cord-006870-f5w6fw6q 3283 5 study study NN cord-006870-f5w6fw6q 3283 6 is be VBZ cord-006870-f5w6fw6q 3283 7 warranted warrant VBN cord-006870-f5w6fw6q 3283 8 . . . cord-006870-f5w6fw6q 3284 1 Arterial arterial JJ cord-006870-f5w6fw6q 3284 2 Subdural Subdural NNP cord-006870-f5w6fw6q 3284 3 Hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3284 4 ( ( -LRB- cord-006870-f5w6fw6q 3284 5 SDH SDH NNP cord-006870-f5w6fw6q 3284 6 ) ) -RRB- cord-006870-f5w6fw6q 3284 7 is be VBZ cord-006870-f5w6fw6q 3284 8 a a DT cord-006870-f5w6fw6q 3284 9 rare rare JJ cord-006870-f5w6fw6q 3284 10 but but CC cord-006870-f5w6fw6q 3284 11 potentially potentially RB cord-006870-f5w6fw6q 3284 12 devastating devastating JJ cord-006870-f5w6fw6q 3284 13 neurologic neurologic JJ cord-006870-f5w6fw6q 3284 14 entity entity NN cord-006870-f5w6fw6q 3284 15 . . . cord-006870-f5w6fw6q 3285 1 It -PRON- PRP cord-006870-f5w6fw6q 3285 2 has have VBZ cord-006870-f5w6fw6q 3285 3 been be VBN cord-006870-f5w6fw6q 3285 4 associated associate VBN cord-006870-f5w6fw6q 3285 5 with with IN cord-006870-f5w6fw6q 3285 6 ruptured ruptured JJ cord-006870-f5w6fw6q 3285 7 aneurysms aneurysm NNS cord-006870-f5w6fw6q 3285 8 . . . cord-006870-f5w6fw6q 3286 1 We -PRON- PRP cord-006870-f5w6fw6q 3286 2 report report VBP cord-006870-f5w6fw6q 3286 3 a a DT cord-006870-f5w6fw6q 3286 4 case case NN cord-006870-f5w6fw6q 3286 5 - - HYPH cord-006870-f5w6fw6q 3286 6 series series NN cord-006870-f5w6fw6q 3286 7 of of IN cord-006870-f5w6fw6q 3286 8 five five CD cord-006870-f5w6fw6q 3286 9 patients patient NNS cord-006870-f5w6fw6q 3286 10 with with IN cord-006870-f5w6fw6q 3286 11 arterial arterial JJ cord-006870-f5w6fw6q 3286 12 SDH SDH NNP cord-006870-f5w6fw6q 3286 13 and and CC cord-006870-f5w6fw6q 3286 14 their -PRON- PRP$ cord-006870-f5w6fw6q 3286 15 outcomes outcome NNS cord-006870-f5w6fw6q 3286 16 . . . cord-006870-f5w6fw6q 3287 1 A a DT cord-006870-f5w6fw6q 3287 2 retrospective retrospective JJ cord-006870-f5w6fw6q 3287 3 chart chart NN cord-006870-f5w6fw6q 3287 4 review review NN cord-006870-f5w6fw6q 3287 5 of of IN cord-006870-f5w6fw6q 3287 6 our -PRON- PRP$ cord-006870-f5w6fw6q 3287 7 institute institute NN cord-006870-f5w6fw6q 3287 8 's 's POS cord-006870-f5w6fw6q 3287 9 vascular vascular JJ cord-006870-f5w6fw6q 3287 10 database database NN cord-006870-f5w6fw6q 3287 11 was be VBD cord-006870-f5w6fw6q 3287 12 conducted conduct VBN cord-006870-f5w6fw6q 3287 13 using use VBG cord-006870-f5w6fw6q 3287 14 a a DT cord-006870-f5w6fw6q 3287 15 pre pre JJ cord-006870-f5w6fw6q 3287 16 - - JJ cord-006870-f5w6fw6q 3287 17 defined defined JJ cord-006870-f5w6fw6q 3287 18 search search NN cord-006870-f5w6fw6q 3287 19 strategy strategy NN cord-006870-f5w6fw6q 3287 20 including include VBG cord-006870-f5w6fw6q 3287 21 the the DT cord-006870-f5w6fw6q 3287 22 terms term NNS cord-006870-f5w6fw6q 3287 23 " " `` cord-006870-f5w6fw6q 3287 24 aneurysm aneurysm NN cord-006870-f5w6fw6q 3287 25 " " '' cord-006870-f5w6fw6q 3287 26 , , , cord-006870-f5w6fw6q 3287 27 " " `` cord-006870-f5w6fw6q 3287 28 Arterio arterio NN cord-006870-f5w6fw6q 3287 29 - - HYPH cord-006870-f5w6fw6q 3287 30 venous venous JJ cord-006870-f5w6fw6q 3287 31 malformation malformation NN cord-006870-f5w6fw6q 3287 32 " " '' cord-006870-f5w6fw6q 3287 33 , , , cord-006870-f5w6fw6q 3287 34 " " `` cord-006870-f5w6fw6q 3287 35 subdural subdural JJ cord-006870-f5w6fw6q 3287 36 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3287 37 " " '' cord-006870-f5w6fw6q 3287 38 , , , cord-006870-f5w6fw6q 3287 39 and and CC cord-006870-f5w6fw6q 3287 40 " " `` cord-006870-f5w6fw6q 3287 41 dural dural JJ cord-006870-f5w6fw6q 3287 42 Arterio arterio NN cord-006870-f5w6fw6q 3287 43 - - HYPH cord-006870-f5w6fw6q 3287 44 venous venous JJ cord-006870-f5w6fw6q 3287 45 fistula fistula NN cord-006870-f5w6fw6q 3287 46 " " '' cord-006870-f5w6fw6q 3287 47 ( ( -LRB- cord-006870-f5w6fw6q 3287 48 dural dural JJ cord-006870-f5w6fw6q 3287 49 - - HYPH cord-006870-f5w6fw6q 3287 50 AVF AVF NNP cord-006870-f5w6fw6q 3287 51 ) ) -RRB- cord-006870-f5w6fw6q 3287 52 . . . cord-006870-f5w6fw6q 3288 1 Amongst amongst IN cord-006870-f5w6fw6q 3288 2 200 200 CD cord-006870-f5w6fw6q 3288 3 patients patient NNS cord-006870-f5w6fw6q 3288 4 in in IN cord-006870-f5w6fw6q 3288 5 the the DT cord-006870-f5w6fw6q 3288 6 database database NN cord-006870-f5w6fw6q 3288 7 , , , cord-006870-f5w6fw6q 3288 8 five five CD cord-006870-f5w6fw6q 3288 9 cases case NNS cord-006870-f5w6fw6q 3288 10 were be VBD cord-006870-f5w6fw6q 3288 11 identified identify VBN cord-006870-f5w6fw6q 3288 12 with with IN cord-006870-f5w6fw6q 3288 13 ages age NNS cord-006870-f5w6fw6q 3288 14 ranging range VBG cord-006870-f5w6fw6q 3288 15 from from IN cord-006870-f5w6fw6q 3288 16 43 43 CD cord-006870-f5w6fw6q 3288 17 to to IN cord-006870-f5w6fw6q 3288 18 78 78 CD cord-006870-f5w6fw6q 3288 19 ( ( -LRB- cord-006870-f5w6fw6q 3288 20 four four CD cord-006870-f5w6fw6q 3288 21 females female NNS cord-006870-f5w6fw6q 3288 22 ) ) -RRB- cord-006870-f5w6fw6q 3288 23 . . . cord-006870-f5w6fw6q 3289 1 Four four CD cord-006870-f5w6fw6q 3289 2 had have VBD cord-006870-f5w6fw6q 3289 3 SDH SDH NNP cord-006870-f5w6fw6q 3289 4 due due IN cord-006870-f5w6fw6q 3289 5 to to IN cord-006870-f5w6fw6q 3289 6 aneurysm aneurysm NN cord-006870-f5w6fw6q 3289 7 ( ( -LRB- cord-006870-f5w6fw6q 3289 8 two two CD cord-006870-f5w6fw6q 3289 9 internal internal JJ cord-006870-f5w6fw6q 3289 10 - - HYPH cord-006870-f5w6fw6q 3289 11 carotid carotid NN cord-006870-f5w6fw6q 3289 12 , , , cord-006870-f5w6fw6q 3289 13 one one CD cord-006870-f5w6fw6q 3289 14 middle middle JJ cord-006870-f5w6fw6q 3289 15 - - HYPH cord-006870-f5w6fw6q 3289 16 cerebral cerebral JJ cord-006870-f5w6fw6q 3289 17 , , , cord-006870-f5w6fw6q 3289 18 and and CC cord-006870-f5w6fw6q 3289 19 one one CD cord-006870-f5w6fw6q 3289 20 posteriorcerebral posteriorcerebral JJ cord-006870-f5w6fw6q 3289 21 artery artery NN cord-006870-f5w6fw6q 3289 22 ; ; . cord-006870-f5w6fw6q 3290 1 one one CD cord-006870-f5w6fw6q 3290 2 had have VBD cord-006870-f5w6fw6q 3290 3 parieto parieto NN cord-006870-f5w6fw6q 3290 4 - - HYPH cord-006870-f5w6fw6q 3290 5 occipital occipital JJ cord-006870-f5w6fw6q 3290 6 dural dural JJ cord-006870-f5w6fw6q 3290 7 AV av NN cord-006870-f5w6fw6q 3290 8 - - HYPH cord-006870-f5w6fw6q 3290 9 fistula fistula NN cord-006870-f5w6fw6q 3290 10 . . . cord-006870-f5w6fw6q 3291 1 No no DT cord-006870-f5w6fw6q 3291 2 patient patient NN cord-006870-f5w6fw6q 3291 3 had have VBD cord-006870-f5w6fw6q 3291 4 preceding precede VBG cord-006870-f5w6fw6q 3291 5 head head NN cord-006870-f5w6fw6q 3291 6 - - HYPH cord-006870-f5w6fw6q 3291 7 trauma trauma NN cord-006870-f5w6fw6q 3291 8 or or CC cord-006870-f5w6fw6q 3291 9 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 3291 10 . . . cord-006870-f5w6fw6q 3292 1 Of of IN cord-006870-f5w6fw6q 3292 2 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 3292 3 patients patient NNS cord-006870-f5w6fw6q 3292 4 , , , cord-006870-f5w6fw6q 3292 5 one one PRP cord-006870-f5w6fw6q 3292 6 had have VBD cord-006870-f5w6fw6q 3292 7 no no DT cord-006870-f5w6fw6q 3292 8 SAH sah NN cord-006870-f5w6fw6q 3292 9 . . . cord-006870-f5w6fw6q 3293 1 On on IN cord-006870-f5w6fw6q 3293 2 admission admission NN cord-006870-f5w6fw6q 3293 3 CT CT NNP cord-006870-f5w6fw6q 3293 4 - - HYPH cord-006870-f5w6fw6q 3293 5 Head Head NNP cord-006870-f5w6fw6q 3293 6 imaging imaging NN cord-006870-f5w6fw6q 3293 7 , , , cord-006870-f5w6fw6q 3293 8 the the DT cord-006870-f5w6fw6q 3293 9 mean mean JJ cord-006870-f5w6fw6q 3293 10 - - HYPH cord-006870-f5w6fw6q 3293 11 SDH sdh NN cord-006870-f5w6fw6q 3293 12 size size NN cord-006870-f5w6fw6q 3293 13 was be VBD cord-006870-f5w6fw6q 3293 14 10.88 10.88 CD cord-006870-f5w6fw6q 3293 15 mm mm NNP cord-006870-f5w6fw6q 3293 16 ( ( -LRB- cord-006870-f5w6fw6q 3293 17 SD SD NNP cord-006870-f5w6fw6q 3293 18 3.24 3.24 CD cord-006870-f5w6fw6q 3293 19 ; ; : cord-006870-f5w6fw6q 3293 20 range range VBP cord-006870-f5w6fw6q 3293 21 7.4 7.4 CD cord-006870-f5w6fw6q 3293 22 - - SYM cord-006870-f5w6fw6q 3293 23 15 15 CD cord-006870-f5w6fw6q 3293 24 mm mm NNP cord-006870-f5w6fw6q 3293 25 ) ) -RRB- cord-006870-f5w6fw6q 3293 26 , , , cord-006870-f5w6fw6q 3293 27 and and CC cord-006870-f5w6fw6q 3293 28 mean mean VB cord-006870-f5w6fw6q 3293 29 midline midline JJ cord-006870-f5w6fw6q 3293 30 - - HYPH cord-006870-f5w6fw6q 3293 31 shift shift NN cord-006870-f5w6fw6q 3293 32 ( ( -LRB- cord-006870-f5w6fw6q 3293 33 MLS MLS NNP cord-006870-f5w6fw6q 3293 34 ) ) -RRB- cord-006870-f5w6fw6q 3293 35 was be VBD cord-006870-f5w6fw6q 3293 36 12.64 12.64 CD cord-006870-f5w6fw6q 3293 37 mm mm NNS cord-006870-f5w6fw6q 3293 38 ( ( -LRB- cord-006870-f5w6fw6q 3293 39 SD SD NNP cord-006870-f5w6fw6q 3293 40 2.49 2.49 CD cord-006870-f5w6fw6q 3293 41 ; ; : cord-006870-f5w6fw6q 3294 1 range range NNP cord-006870-f5w6fw6q 3294 2 9 9 CD cord-006870-f5w6fw6q 3294 3 - - SYM cord-006870-f5w6fw6q 3294 4 15 15 CD cord-006870-f5w6fw6q 3294 5 mm mm CD cord-006870-f5w6fw6q 3294 6 ) ) -RRB- cord-006870-f5w6fw6q 3294 7 . . . cord-006870-f5w6fw6q 3295 1 The the DT cord-006870-f5w6fw6q 3295 2 mean mean JJ cord-006870-f5w6fw6q 3295 3 ratio ratio NN cord-006870-f5w6fw6q 3295 4 between between IN cord-006870-f5w6fw6q 3295 5 SDH SDH NNP cord-006870-f5w6fw6q 3295 6 - - HYPH cord-006870-f5w6fw6q 3295 7 size size NN cord-006870-f5w6fw6q 3295 8 and and CC cord-006870-f5w6fw6q 3295 9 MLS MLS NNP cord-006870-f5w6fw6q 3295 10 was be VBD cord-006870-f5w6fw6q 3295 11 1.16 1.16 CD cord-006870-f5w6fw6q 3295 12 ( ( -LRB- cord-006870-f5w6fw6q 3295 13 SD SD NNP cord-006870-f5w6fw6q 3295 14 0.25 0.25 CD cord-006870-f5w6fw6q 3295 15 ) ) -RRB- cord-006870-f5w6fw6q 3295 16 . . . cord-006870-f5w6fw6q 3296 1 In in IN cord-006870-f5w6fw6q 3296 2 a a DT cord-006870-f5w6fw6q 3296 3 historic historic JJ cord-006870-f5w6fw6q 3296 4 cohort cohort NN cord-006870-f5w6fw6q 3296 5 of of IN cord-006870-f5w6fw6q 3296 6 acute acute JJ cord-006870-f5w6fw6q 3296 7 subdural subdural JJ cord-006870-f5w6fw6q 3296 8 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3296 9 of of IN cord-006870-f5w6fw6q 3296 10 non non JJ cord-006870-f5w6fw6q 3296 11 - - JJ cord-006870-f5w6fw6q 3296 12 arterial arterial JJ cord-006870-f5w6fw6q 3296 13 etiology etiology NN cord-006870-f5w6fw6q 3296 14 ; ; : cord-006870-f5w6fw6q 3296 15 the the DT cord-006870-f5w6fw6q 3296 16 mean mean JJ cord-006870-f5w6fw6q 3296 17 size size NN cord-006870-f5w6fw6q 3296 18 of of IN cord-006870-f5w6fw6q 3296 19 SDH SDH NNP cord-006870-f5w6fw6q 3296 20 was be VBD cord-006870-f5w6fw6q 3296 21 8.0 8.0 CD cord-006870-f5w6fw6q 3296 22 mm mm NNS cord-006870-f5w6fw6q 3296 23 and and CC cord-006870-f5w6fw6q 3296 24 the the DT cord-006870-f5w6fw6q 3296 25 mean mean JJ cord-006870-f5w6fw6q 3296 26 MLS MLS NNP cord-006870-f5w6fw6q 3296 27 was be VBD cord-006870-f5w6fw6q 3296 28 4.6 4.6 CD cord-006870-f5w6fw6q 3296 29 mm mm NNS cord-006870-f5w6fw6q 3296 30 . . . cord-006870-f5w6fw6q 3297 1 Ratio ratio NN cord-006870-f5w6fw6q 3297 2 of of IN cord-006870-f5w6fw6q 3297 3 MLS MLS NNP cord-006870-f5w6fw6q 3297 4 : : : cord-006870-f5w6fw6q 3298 1 SDH SDH NNP cord-006870-f5w6fw6q 3298 2 size size NN cord-006870-f5w6fw6q 3298 3 was be VBD cord-006870-f5w6fw6q 3298 4 0.56 0.56 CD cord-006870-f5w6fw6q 3298 5 . . . cord-006870-f5w6fw6q 3299 1 In in IN cord-006870-f5w6fw6q 3299 2 our -PRON- PRP$ cord-006870-f5w6fw6q 3299 3 series series NN cord-006870-f5w6fw6q 3299 4 , , , cord-006870-f5w6fw6q 3299 5 three three CD cord-006870-f5w6fw6q 3299 6 patients patient NNS cord-006870-f5w6fw6q 3299 7 with with IN cord-006870-f5w6fw6q 3299 8 aneurysms aneurysm NNS cord-006870-f5w6fw6q 3299 9 had have VBD cord-006870-f5w6fw6q 3299 10 decompressive decompressive JJ cord-006870-f5w6fw6q 3299 11 - - HYPH cord-006870-f5w6fw6q 3299 12 craniectomy craniectomy NN cord-006870-f5w6fw6q 3299 13 , , , cord-006870-f5w6fw6q 3299 14 one one PRP cord-006870-f5w6fw6q 3299 15 had have VBD cord-006870-f5w6fw6q 3299 16 mini mini NN cord-006870-f5w6fw6q 3299 17 - - NN cord-006870-f5w6fw6q 3299 18 craniotomy craniotomy NN cord-006870-f5w6fw6q 3299 19 for for IN cord-006870-f5w6fw6q 3299 20 SDH SDH NNP cord-006870-f5w6fw6q 3299 21 evacuation evacuation NN cord-006870-f5w6fw6q 3299 22 ; ; : cord-006870-f5w6fw6q 3299 23 the the DT cord-006870-f5w6fw6q 3299 24 patient patient NN cord-006870-f5w6fw6q 3299 25 with with IN cord-006870-f5w6fw6q 3299 26 dural dural JJ cord-006870-f5w6fw6q 3299 27 - - HYPH cord-006870-f5w6fw6q 3299 28 AVF AVF NNP cord-006870-f5w6fw6q 3299 29 had have VBD cord-006870-f5w6fw6q 3299 30 coiling coil VBG cord-006870-f5w6fw6q 3299 31 and and CC cord-006870-f5w6fw6q 3299 32 mini mini JJ cord-006870-f5w6fw6q 3299 33 - - NN cord-006870-f5w6fw6q 3299 34 craniotomy craniotomy NN cord-006870-f5w6fw6q 3299 35 for for IN cord-006870-f5w6fw6q 3299 36 SDH SDH NNP cord-006870-f5w6fw6q 3299 37 evacuation evacuation NN cord-006870-f5w6fw6q 3299 38 . . . cord-006870-f5w6fw6q 3300 1 Four four CD cord-006870-f5w6fw6q 3300 2 patients patient NNS cord-006870-f5w6fw6q 3300 3 had have VBD cord-006870-f5w6fw6q 3300 4 died die VBN cord-006870-f5w6fw6q 3300 5 during during IN cord-006870-f5w6fw6q 3300 6 hospitalization hospitalization NN cord-006870-f5w6fw6q 3300 7 , , , cord-006870-f5w6fw6q 3300 8 whereas whereas IN cord-006870-f5w6fw6q 3300 9 patient patient JJ cord-006870-f5w6fw6q 3300 10 with with IN cord-006870-f5w6fw6q 3300 11 dural dural JJ cord-006870-f5w6fw6q 3300 12 - - HYPH cord-006870-f5w6fw6q 3300 13 AVF AVF NNP cord-006870-f5w6fw6q 3300 14 recovered recover VBD cord-006870-f5w6fw6q 3300 15 to to IN cord-006870-f5w6fw6q 3300 16 baseline baseline JJ cord-006870-f5w6fw6q 3300 17 functional functional JJ cord-006870-f5w6fw6q 3300 18 - - HYPH cord-006870-f5w6fw6q 3300 19 status status NN cord-006870-f5w6fw6q 3300 20 at at IN cord-006870-f5w6fw6q 3300 21 6-month 6-month CD cord-006870-f5w6fw6q 3300 22 follow follow NN cord-006870-f5w6fw6q 3300 23 - - HYPH cord-006870-f5w6fw6q 3300 24 up up NN cord-006870-f5w6fw6q 3300 25 . . . cord-006870-f5w6fw6q 3301 1 Arterial arterial JJ cord-006870-f5w6fw6q 3301 2 SDH SDH NNP cord-006870-f5w6fw6q 3301 3 is be VBZ cord-006870-f5w6fw6q 3301 4 a a DT cord-006870-f5w6fw6q 3301 5 rare rare JJ cord-006870-f5w6fw6q 3301 6 entity entity NN cord-006870-f5w6fw6q 3301 7 and and CC cord-006870-f5w6fw6q 3301 8 may may MD cord-006870-f5w6fw6q 3301 9 present present VB cord-006870-f5w6fw6q 3301 10 without without IN cord-006870-f5w6fw6q 3301 11 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3301 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3301 13 and and CC cord-006870-f5w6fw6q 3301 14 any any DT cord-006870-f5w6fw6q 3301 15 preceding precede VBG cord-006870-f5w6fw6q 3301 16 head head NN cord-006870-f5w6fw6q 3301 17 - - HYPH cord-006870-f5w6fw6q 3301 18 trauma trauma NN cord-006870-f5w6fw6q 3301 19 . . . cord-006870-f5w6fw6q 3302 1 The the DT cord-006870-f5w6fw6q 3302 2 degree degree NN cord-006870-f5w6fw6q 3302 3 of of IN cord-006870-f5w6fw6q 3302 4 midline midline JJ cord-006870-f5w6fw6q 3302 5 - - HYPH cord-006870-f5w6fw6q 3302 6 shift shift NN cord-006870-f5w6fw6q 3302 7 is be VBZ cord-006870-f5w6fw6q 3302 8 usually usually RB cord-006870-f5w6fw6q 3302 9 out out IN cord-006870-f5w6fw6q 3302 10 of of IN cord-006870-f5w6fw6q 3302 11 proportion proportion NN cord-006870-f5w6fw6q 3302 12 to to IN cord-006870-f5w6fw6q 3302 13 SDH SDH NNP cord-006870-f5w6fw6q 3302 14 size size NN cord-006870-f5w6fw6q 3302 15 . . . cord-006870-f5w6fw6q 3303 1 There there EX cord-006870-f5w6fw6q 3303 2 should should MD cord-006870-f5w6fw6q 3303 3 be be VB cord-006870-f5w6fw6q 3303 4 a a DT cord-006870-f5w6fw6q 3303 5 low low JJ cord-006870-f5w6fw6q 3303 6 threshold threshold NN cord-006870-f5w6fw6q 3303 7 to to TO cord-006870-f5w6fw6q 3303 8 obtain obtain VB cord-006870-f5w6fw6q 3303 9 vessel vessel NN cord-006870-f5w6fw6q 3303 10 imaging imaging NN cord-006870-f5w6fw6q 3303 11 in in IN cord-006870-f5w6fw6q 3303 12 cases case NNS cord-006870-f5w6fw6q 3303 13 of of IN cord-006870-f5w6fw6q 3303 14 SDH SDH NNP cord-006870-f5w6fw6q 3303 15 with with IN cord-006870-f5w6fw6q 3303 16 no no DT cord-006870-f5w6fw6q 3303 17 clear clear JJ cord-006870-f5w6fw6q 3303 18 trauma trauma NN cord-006870-f5w6fw6q 3303 19 history history NN cord-006870-f5w6fw6q 3303 20 . . . cord-006870-f5w6fw6q 3304 1 MLS MLS NNP cord-006870-f5w6fw6q 3304 2 : : : cord-006870-f5w6fw6q 3305 1 SDH SDH NNP cord-006870-f5w6fw6q 3305 2 ratio ratio NN cord-006870-f5w6fw6q 3305 3 may may MD cord-006870-f5w6fw6q 3305 4 be be VB cord-006870-f5w6fw6q 3305 5 a a DT cord-006870-f5w6fw6q 3305 6 useful useful JJ cord-006870-f5w6fw6q 3305 7 screening screening NN cord-006870-f5w6fw6q 3305 8 tool tool NN cord-006870-f5w6fw6q 3305 9 for for IN cord-006870-f5w6fw6q 3305 10 possibility possibility NN cord-006870-f5w6fw6q 3305 11 of of IN cord-006870-f5w6fw6q 3305 12 arterial arterial JJ cord-006870-f5w6fw6q 3305 13 SDH SDH NNP cord-006870-f5w6fw6q 3305 14 especially especially RB cord-006870-f5w6fw6q 3305 15 in in IN cord-006870-f5w6fw6q 3305 16 absence absence NN cord-006870-f5w6fw6q 3305 17 of of IN cord-006870-f5w6fw6q 3305 18 trauma trauma NN cord-006870-f5w6fw6q 3305 19 and and CC cord-006870-f5w6fw6q 3305 20 may may MD cord-006870-f5w6fw6q 3305 21 reflect reflect VB cord-006870-f5w6fw6q 3305 22 rate rate NN cord-006870-f5w6fw6q 3305 23 of of IN cord-006870-f5w6fw6q 3305 24 bleeding bleed VBG cord-006870-f5w6fw6q 3305 25 . . . cord-006870-f5w6fw6q 3306 1 Neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3306 2 medications medication NNS cord-006870-f5w6fw6q 3306 3 ( ( -LRB- cord-006870-f5w6fw6q 3306 4 amantadine amantadine NNP cord-006870-f5w6fw6q 3306 5 and and CC cord-006870-f5w6fw6q 3306 6 modafinil modafinil NN cord-006870-f5w6fw6q 3306 7 ) ) -RRB- cord-006870-f5w6fw6q 3306 8 are be VBP cord-006870-f5w6fw6q 3306 9 sometimes sometimes RB cord-006870-f5w6fw6q 3306 10 prescribed prescribe VBN cord-006870-f5w6fw6q 3306 11 after after IN cord-006870-f5w6fw6q 3306 12 acute acute JJ cord-006870-f5w6fw6q 3306 13 nontraumatic nontraumatic JJ cord-006870-f5w6fw6q 3306 14 brain brain NN cord-006870-f5w6fw6q 3306 15 injury injury NN cord-006870-f5w6fw6q 3306 16 to to TO cord-006870-f5w6fw6q 3306 17 facilitate facilitate VB cord-006870-f5w6fw6q 3306 18 wakening wakening NN cord-006870-f5w6fw6q 3306 19 and and CC cord-006870-f5w6fw6q 3306 20 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 3306 21 participation participation NN cord-006870-f5w6fw6q 3306 22 ; ; : cord-006870-f5w6fw6q 3306 23 the the DT cord-006870-f5w6fw6q 3306 24 safety safety NN cord-006870-f5w6fw6q 3306 25 and and CC cord-006870-f5w6fw6q 3306 26 effectiveness effectiveness NN cord-006870-f5w6fw6q 3306 27 of of IN cord-006870-f5w6fw6q 3306 28 this this DT cord-006870-f5w6fw6q 3306 29 practice practice NN cord-006870-f5w6fw6q 3306 30 is be VBZ cord-006870-f5w6fw6q 3306 31 unknown unknown JJ cord-006870-f5w6fw6q 3306 32 . . . cord-006870-f5w6fw6q 3307 1 Following follow VBG cord-006870-f5w6fw6q 3307 2 a a DT cord-006870-f5w6fw6q 3307 3 retrospective retrospective JJ cord-006870-f5w6fw6q 3307 4 evaluation evaluation NN cord-006870-f5w6fw6q 3307 5 of of IN cord-006870-f5w6fw6q 3307 6 our -PRON- PRP$ cord-006870-f5w6fw6q 3307 7 experiences experience NNS cord-006870-f5w6fw6q 3307 8 , , , cord-006870-f5w6fw6q 3307 9 we -PRON- PRP cord-006870-f5w6fw6q 3307 10 characterized characterize VBD cord-006870-f5w6fw6q 3307 11 anticipated anticipate VBN cord-006870-f5w6fw6q 3307 12 challenges challenge NNS cord-006870-f5w6fw6q 3307 13 to to IN cord-006870-f5w6fw6q 3307 14 designing design VBG cord-006870-f5w6fw6q 3307 15 a a DT cord-006870-f5w6fw6q 3307 16 prospective prospective JJ cord-006870-f5w6fw6q 3307 17 randomized randomized JJ cord-006870-f5w6fw6q 3307 18 trial trial NN cord-006870-f5w6fw6q 3307 19 of of IN cord-006870-f5w6fw6q 3307 20 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3307 21 medications medication NNS cord-006870-f5w6fw6q 3307 22 to to TO cord-006870-f5w6fw6q 3307 23 promote promote VB cord-006870-f5w6fw6q 3307 24 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 3307 25 participation participation NN cord-006870-f5w6fw6q 3307 26 after after IN cord-006870-f5w6fw6q 3307 27 acute acute JJ cord-006870-f5w6fw6q 3307 28 non non JJ cord-006870-f5w6fw6q 3307 29 - - JJ cord-006870-f5w6fw6q 3307 30 traumatic traumatic JJ cord-006870-f5w6fw6q 3307 31 brain brain NN cord-006870-f5w6fw6q 3307 32 injury injury NN cord-006870-f5w6fw6q 3307 33 . . . cord-006870-f5w6fw6q 3308 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 3308 2 chart chart NN cord-006870-f5w6fw6q 3308 3 review review NN cord-006870-f5w6fw6q 3308 4 of of IN cord-006870-f5w6fw6q 3308 5 patients patient NNS cord-006870-f5w6fw6q 3308 6 over over IN cord-006870-f5w6fw6q 3308 7 with with IN cord-006870-f5w6fw6q 3308 8 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3308 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3308 10 ( ( -LRB- cord-006870-f5w6fw6q 3308 11 n=17 n=17 NNP cord-006870-f5w6fw6q 3308 12 ) ) -RRB- cord-006870-f5w6fw6q 3308 13 , , , cord-006870-f5w6fw6q 3308 14 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3308 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3308 16 ( ( -LRB- cord-006870-f5w6fw6q 3308 17 n=41 n=41 RB cord-006870-f5w6fw6q 3308 18 ) ) -RRB- cord-006870-f5w6fw6q 3308 19 and and CC cord-006870-f5w6fw6q 3308 20 ischemic ischemic JJ cord-006870-f5w6fw6q 3308 21 stroke stroke NN cord-006870-f5w6fw6q 3308 22 ( ( -LRB- cord-006870-f5w6fw6q 3308 23 n=30 n=30 NNP cord-006870-f5w6fw6q 3308 24 ) ) -RRB- cord-006870-f5w6fw6q 3308 25 who who WP cord-006870-f5w6fw6q 3308 26 received receive VBD cord-006870-f5w6fw6q 3308 27 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3308 28 medications medication NNS cord-006870-f5w6fw6q 3308 29 over over IN cord-006870-f5w6fw6q 3308 30 a a DT cord-006870-f5w6fw6q 3308 31 period period NN cord-006870-f5w6fw6q 3308 32 of of IN cord-006870-f5w6fw6q 3308 33 43 43 CD cord-006870-f5w6fw6q 3308 34 months month NNS cord-006870-f5w6fw6q 3308 35 . . . cord-006870-f5w6fw6q 3309 1 Data datum NNS cord-006870-f5w6fw6q 3309 2 regarding regard VBG cord-006870-f5w6fw6q 3309 3 clinical clinical JJ cord-006870-f5w6fw6q 3309 4 course course NN cord-006870-f5w6fw6q 3309 5 and and CC cord-006870-f5w6fw6q 3309 6 potential potential JJ cord-006870-f5w6fw6q 3309 7 confounders confounder NNS cord-006870-f5w6fw6q 3309 8 to to IN cord-006870-f5w6fw6q 3309 9 assessing assess VBG cord-006870-f5w6fw6q 3309 10 response response NN cord-006870-f5w6fw6q 3309 11 were be VBD cord-006870-f5w6fw6q 3309 12 collected collect VBN cord-006870-f5w6fw6q 3309 13 . . . cord-006870-f5w6fw6q 3310 1 Continuous continuous JJ cord-006870-f5w6fw6q 3310 2 data datum NNS cord-006870-f5w6fw6q 3310 3 are be VBP cord-006870-f5w6fw6q 3310 4 reported report VBN cord-006870-f5w6fw6q 3310 5 as as IN cord-006870-f5w6fw6q 3310 6 median median JJ cord-006870-f5w6fw6q 3310 7 and and CC cord-006870-f5w6fw6q 3310 8 interquartile interquartile JJ cord-006870-f5w6fw6q 3310 9 range range NN cord-006870-f5w6fw6q 3310 10 . . . cord-006870-f5w6fw6q 3311 1 Neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3311 2 medications medication NNS cord-006870-f5w6fw6q 3311 3 were be VBD cord-006870-f5w6fw6q 3311 4 initiated initiate VBN cord-006870-f5w6fw6q 3311 5 in in IN cord-006870-f5w6fw6q 3311 6 88 88 CD cord-006870-f5w6fw6q 3311 7 patients patient NNS cord-006870-f5w6fw6q 3311 8 at at IN cord-006870-f5w6fw6q 3311 9 a a DT cord-006870-f5w6fw6q 3311 10 median median NN cord-006870-f5w6fw6q 3311 11 of of IN cord-006870-f5w6fw6q 3311 12 7 7 CD cord-006870-f5w6fw6q 3311 13 ( ( -LRB- cord-006870-f5w6fw6q 3311 14 5 5 CD cord-006870-f5w6fw6q 3311 15 - - SYM cord-006870-f5w6fw6q 3311 16 13 13 CD cord-006870-f5w6fw6q 3311 17 ) ) -RRB- cord-006870-f5w6fw6q 3311 18 days day NNS cord-006870-f5w6fw6q 3311 19 after after IN cord-006870-f5w6fw6q 3311 20 hospital hospital NN cord-006870-f5w6fw6q 3311 21 admission admission NN cord-006870-f5w6fw6q 3311 22 , , , cord-006870-f5w6fw6q 3311 23 for for IN cord-006870-f5w6fw6q 3311 24 hypersomnolence hypersomnolence NN cord-006870-f5w6fw6q 3311 25 68 68 CD cord-006870-f5w6fw6q 3311 26 ( ( -LRB- cord-006870-f5w6fw6q 3311 27 77 77 CD cord-006870-f5w6fw6q 3311 28 % % NN cord-006870-f5w6fw6q 3311 29 ) ) -RRB- cord-006870-f5w6fw6q 3311 30 , , , cord-006870-f5w6fw6q 3311 31 not not RB cord-006870-f5w6fw6q 3311 32 following follow VBG cord-006870-f5w6fw6q 3311 33 commands command NNS cord-006870-f5w6fw6q 3311 34 28 28 CD cord-006870-f5w6fw6q 3311 35 ( ( -LRB- cord-006870-f5w6fw6q 3311 36 32 32 CD cord-006870-f5w6fw6q 3311 37 % % NN cord-006870-f5w6fw6q 3311 38 ) ) -RRB- cord-006870-f5w6fw6q 3311 39 , , , cord-006870-f5w6fw6q 3311 40 lack lack NN cord-006870-f5w6fw6q 3311 41 of of IN cord-006870-f5w6fw6q 3311 42 eye eye NN cord-006870-f5w6fw6q 3311 43 opening opening NN cord-006870-f5w6fw6q 3311 44 25 25 CD cord-006870-f5w6fw6q 3311 45 ( ( -LRB- cord-006870-f5w6fw6q 3311 46 28 28 CD cord-006870-f5w6fw6q 3311 47 % % NN cord-006870-f5w6fw6q 3311 48 ) ) -RRB- cord-006870-f5w6fw6q 3311 49 , , , cord-006870-f5w6fw6q 3311 50 and/or and/or CC cord-006870-f5w6fw6q 3311 51 low low JJ cord-006870-f5w6fw6q 3311 52 GCS GCS NNP cord-006870-f5w6fw6q 3311 53 15 15 CD cord-006870-f5w6fw6q 3311 54 ( ( -LRB- cord-006870-f5w6fw6q 3311 55 17 17 CD cord-006870-f5w6fw6q 3311 56 % % NN cord-006870-f5w6fw6q 3311 57 ) ) -RRB- cord-006870-f5w6fw6q 3311 58 . . . cord-006870-f5w6fw6q 3312 1 Thirty thirty CD cord-006870-f5w6fw6q 3312 2 - - HYPH cord-006870-f5w6fw6q 3312 3 nine nine CD cord-006870-f5w6fw6q 3312 4 ( ( -LRB- cord-006870-f5w6fw6q 3312 5 44 44 CD cord-006870-f5w6fw6q 3312 6 % % NN cord-006870-f5w6fw6q 3312 7 ) ) -RRB- cord-006870-f5w6fw6q 3312 8 patients patient NNS cord-006870-f5w6fw6q 3312 9 were be VBD cord-006870-f5w6fw6q 3312 10 receiving receive VBG cord-006870-f5w6fw6q 3312 11 sedatives sedative NNS cord-006870-f5w6fw6q 3312 12 or or CC cord-006870-f5w6fw6q 3312 13 opioids opioid NNS cord-006870-f5w6fw6q 3312 14 at at IN cord-006870-f5w6fw6q 3312 15 the the DT cord-006870-f5w6fw6q 3312 16 time time NN cord-006870-f5w6fw6q 3312 17 of of IN cord-006870-f5w6fw6q 3312 18 neurostimulant(s neurostimulant(s NNP cord-006870-f5w6fw6q 3312 19 ) ) -RRB- cord-006870-f5w6fw6q 3312 20 initiation initiation NN cord-006870-f5w6fw6q 3312 21 . . . cord-006870-f5w6fw6q 3313 1 Twenty twenty CD cord-006870-f5w6fw6q 3313 2 - - HYPH cord-006870-f5w6fw6q 3313 3 two two CD cord-006870-f5w6fw6q 3313 4 ( ( -LRB- cord-006870-f5w6fw6q 3313 5 25 25 CD cord-006870-f5w6fw6q 3313 6 % % NN cord-006870-f5w6fw6q 3313 7 ) ) -RRB- cord-006870-f5w6fw6q 3313 8 patients patient NNS cord-006870-f5w6fw6q 3313 9 received receive VBD cord-006870-f5w6fw6q 3313 10 newly newly RB cord-006870-f5w6fw6q 3313 11 prescribed prescribe VBN cord-006870-f5w6fw6q 3313 12 sedatives sedative NNS cord-006870-f5w6fw6q 3313 13 or or CC cord-006870-f5w6fw6q 3313 14 opioids opioid NNS cord-006870-f5w6fw6q 3313 15 after after IN cord-006870-f5w6fw6q 3313 16 neurostimulant(s neurostimulant(s JJ cord-006870-f5w6fw6q 3313 17 ) ) -RRB- cord-006870-f5w6fw6q 3313 18 initiation initiation NN cord-006870-f5w6fw6q 3313 19 . . . cord-006870-f5w6fw6q 3314 1 Potentially potentially RB cord-006870-f5w6fw6q 3314 2 sedating sedate VBG cord-006870-f5w6fw6q 3314 3 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 3314 4 medications medication NNS cord-006870-f5w6fw6q 3314 5 were be VBD cord-006870-f5w6fw6q 3314 6 prescribed prescribe VBN cord-006870-f5w6fw6q 3314 7 to to IN cord-006870-f5w6fw6q 3314 8 14 14 CD cord-006870-f5w6fw6q 3314 9 ( ( -LRB- cord-006870-f5w6fw6q 3314 10 16 16 CD cord-006870-f5w6fw6q 3314 11 % % NN cord-006870-f5w6fw6q 3314 12 ) ) -RRB- cord-006870-f5w6fw6q 3314 13 of of IN cord-006870-f5w6fw6q 3314 14 patients patient NNS cord-006870-f5w6fw6q 3314 15 . . . cord-006870-f5w6fw6q 3315 1 Twenty twenty CD cord-006870-f5w6fw6q 3315 2 - - HYPH cord-006870-f5w6fw6q 3315 3 two two CD cord-006870-f5w6fw6q 3315 4 ( ( -LRB- cord-006870-f5w6fw6q 3315 5 25 25 CD cord-006870-f5w6fw6q 3315 6 % % NN cord-006870-f5w6fw6q 3315 7 ) ) -RRB- cord-006870-f5w6fw6q 3315 8 patients patient NNS cord-006870-f5w6fw6q 3315 9 were be VBD cord-006870-f5w6fw6q 3315 10 intubated intubate VBN cord-006870-f5w6fw6q 3315 11 at at IN cord-006870-f5w6fw6q 3315 12 the the DT cord-006870-f5w6fw6q 3315 13 time time NN cord-006870-f5w6fw6q 3315 14 of of IN cord-006870-f5w6fw6q 3315 15 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3315 16 initiation initiation NN cord-006870-f5w6fw6q 3315 17 confounding confound VBG cord-006870-f5w6fw6q 3315 18 the the DT cord-006870-f5w6fw6q 3315 19 GCS GCS NNP cord-006870-f5w6fw6q 3315 20 - - HYPH cord-006870-f5w6fw6q 3315 21 V. V. NNP cord-006870-f5w6fw6q 3315 22 Potentially potentially RB cord-006870-f5w6fw6q 3315 23 confounding confound VBG cord-006870-f5w6fw6q 3315 24 clinical clinical JJ cord-006870-f5w6fw6q 3315 25 factors factor NNS cord-006870-f5w6fw6q 3315 26 included include VBD cord-006870-f5w6fw6q 3315 27 hydrocephalus hydrocephalus NNP cord-006870-f5w6fw6q 3315 28 37 37 CD cord-006870-f5w6fw6q 3315 29 ( ( -LRB- cord-006870-f5w6fw6q 3315 30 42 42 CD cord-006870-f5w6fw6q 3315 31 % % NN cord-006870-f5w6fw6q 3315 32 ) ) -RRB- cord-006870-f5w6fw6q 3315 33 , , , cord-006870-f5w6fw6q 3315 34 vasospasm vasospasm NN cord-006870-f5w6fw6q 3315 35 7 7 CD cord-006870-f5w6fw6q 3315 36 ( ( -LRB- cord-006870-f5w6fw6q 3315 37 8 8 CD cord-006870-f5w6fw6q 3315 38 % % NN cord-006870-f5w6fw6q 3315 39 ) ) -RRB- cord-006870-f5w6fw6q 3315 40 , , , cord-006870-f5w6fw6q 3315 41 and and CC cord-006870-f5w6fw6q 3315 42 seizures seizure NNS cord-006870-f5w6fw6q 3315 43 4 4 CD cord-006870-f5w6fw6q 3315 44 ( ( -LRB- cord-006870-f5w6fw6q 3315 45 5 5 CD cord-006870-f5w6fw6q 3315 46 % % NN cord-006870-f5w6fw6q 3315 47 ) ) -RRB- cord-006870-f5w6fw6q 3315 48 . . . cord-006870-f5w6fw6q 3316 1 Twenty twenty CD cord-006870-f5w6fw6q 3316 2 - - HYPH cord-006870-f5w6fw6q 3316 3 eight eight CD cord-006870-f5w6fw6q 3316 4 ( ( -LRB- cord-006870-f5w6fw6q 3316 5 32 32 CD cord-006870-f5w6fw6q 3316 6 % % NN cord-006870-f5w6fw6q 3316 7 ) ) -RRB- cord-006870-f5w6fw6q 3316 8 of of IN cord-006870-f5w6fw6q 3316 9 patients patient NNS cord-006870-f5w6fw6q 3316 10 had have VBD cord-006870-f5w6fw6q 3316 11 temporary temporary JJ cord-006870-f5w6fw6q 3316 12 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 3316 13 fluid fluid JJ cord-006870-f5w6fw6q 3316 14 diversion diversion NN cord-006870-f5w6fw6q 3316 15 in in IN cord-006870-f5w6fw6q 3316 16 place place NN cord-006870-f5w6fw6q 3316 17 at at IN cord-006870-f5w6fw6q 3316 18 the the DT cord-006870-f5w6fw6q 3316 19 time time NN cord-006870-f5w6fw6q 3316 20 of of IN cord-006870-f5w6fw6q 3316 21 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3316 22 initiation initiation NN cord-006870-f5w6fw6q 3316 23 . . . cord-006870-f5w6fw6q 3317 1 Initiation initiation NN cord-006870-f5w6fw6q 3317 2 and and CC cord-006870-f5w6fw6q 3317 3 titration titration NN cord-006870-f5w6fw6q 3317 4 of of IN cord-006870-f5w6fw6q 3317 5 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3317 6 medications medication NNS cord-006870-f5w6fw6q 3317 7 after after IN cord-006870-f5w6fw6q 3317 8 acute acute JJ cord-006870-f5w6fw6q 3317 9 non non JJ cord-006870-f5w6fw6q 3317 10 - - JJ cord-006870-f5w6fw6q 3317 11 traumatic traumatic JJ cord-006870-f5w6fw6q 3317 12 brain brain NN cord-006870-f5w6fw6q 3317 13 injury injury NN cord-006870-f5w6fw6q 3317 14 was be VBD cord-006870-f5w6fw6q 3317 15 common common JJ cord-006870-f5w6fw6q 3317 16 , , , cord-006870-f5w6fw6q 3317 17 but but CC cord-006870-f5w6fw6q 3317 18 timing timing NN cord-006870-f5w6fw6q 3317 19 and and CC cord-006870-f5w6fw6q 3317 20 indications indication NNS cord-006870-f5w6fw6q 3317 21 varied vary VBN cord-006870-f5w6fw6q 3317 22 widely widely RB cord-006870-f5w6fw6q 3317 23 . . . cord-006870-f5w6fw6q 3318 1 Confounders confounder NNS cord-006870-f5w6fw6q 3318 2 to to IN cord-006870-f5w6fw6q 3318 3 assessing assess VBG cord-006870-f5w6fw6q 3318 4 effectiveness effectiveness NN cord-006870-f5w6fw6q 3318 5 included include VBD cord-006870-f5w6fw6q 3318 6 concomitant concomitant JJ cord-006870-f5w6fw6q 3318 7 sedating sedating JJ cord-006870-f5w6fw6q 3318 8 medications medication NNS cord-006870-f5w6fw6q 3318 9 , , , cord-006870-f5w6fw6q 3318 10 variable variable JJ cord-006870-f5w6fw6q 3318 11 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 3318 12 related relate VBN cord-006870-f5w6fw6q 3318 13 to to IN cord-006870-f5w6fw6q 3318 14 the the DT cord-006870-f5w6fw6q 3318 15 type type NN cord-006870-f5w6fw6q 3318 16 and and CC cord-006870-f5w6fw6q 3318 17 location location NN cord-006870-f5w6fw6q 3318 18 of of IN cord-006870-f5w6fw6q 3318 19 the the DT cord-006870-f5w6fw6q 3318 20 stroke stroke NN cord-006870-f5w6fw6q 3318 21 , , , cord-006870-f5w6fw6q 3318 22 and and CC cord-006870-f5w6fw6q 3318 23 clinical clinical JJ cord-006870-f5w6fw6q 3318 24 factors factor NNS cord-006870-f5w6fw6q 3318 25 like like IN cord-006870-f5w6fw6q 3318 26 seizures seizure NNS cord-006870-f5w6fw6q 3318 27 , , , cord-006870-f5w6fw6q 3318 28 vasospasm vasospasm NN cord-006870-f5w6fw6q 3318 29 , , , cord-006870-f5w6fw6q 3318 30 and and CC cord-006870-f5w6fw6q 3318 31 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 3318 32 . . . cord-006870-f5w6fw6q 3319 1 These these DT cord-006870-f5w6fw6q 3319 2 confounders confounder NNS cord-006870-f5w6fw6q 3319 3 are be VBP cord-006870-f5w6fw6q 3319 4 likely likely JJ cord-006870-f5w6fw6q 3319 5 to to TO cord-006870-f5w6fw6q 3319 6 make make VB cord-006870-f5w6fw6q 3319 7 prospective prospective JJ cord-006870-f5w6fw6q 3319 8 evaluation evaluation NN cord-006870-f5w6fw6q 3319 9 of of IN cord-006870-f5w6fw6q 3319 10 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3319 11 medication medication NN cord-006870-f5w6fw6q 3319 12 effectiveness effectiveness NN cord-006870-f5w6fw6q 3319 13 difficult difficult JJ cord-006870-f5w6fw6q 3319 14 in in IN cord-006870-f5w6fw6q 3319 15 the the DT cord-006870-f5w6fw6q 3319 16 period period NN cord-006870-f5w6fw6q 3319 17 of of IN cord-006870-f5w6fw6q 3319 18 initial initial JJ cord-006870-f5w6fw6q 3319 19 therapy therapy NN cord-006870-f5w6fw6q 3319 20 following follow VBG cord-006870-f5w6fw6q 3319 21 acute acute JJ cord-006870-f5w6fw6q 3319 22 non non JJ cord-006870-f5w6fw6q 3319 23 - - JJ cord-006870-f5w6fw6q 3319 24 traumatic traumatic JJ cord-006870-f5w6fw6q 3319 25 brain brain NN cord-006870-f5w6fw6q 3319 26 injury injury NN cord-006870-f5w6fw6q 3319 27 . . . cord-006870-f5w6fw6q 3320 1 Brain brain NN cord-006870-f5w6fw6q 3320 2 small small JJ cord-006870-f5w6fw6q 3320 3 vessel vessel NN cord-006870-f5w6fw6q 3320 4 disease disease NN cord-006870-f5w6fw6q 3320 5 can can MD cord-006870-f5w6fw6q 3320 6 cause cause VB cord-006870-f5w6fw6q 3320 7 cognitive cognitive JJ cord-006870-f5w6fw6q 3320 8 impairment impairment NN cord-006870-f5w6fw6q 3320 9 via via IN cord-006870-f5w6fw6q 3320 10 ischemic ischemic JJ cord-006870-f5w6fw6q 3320 11 or or CC cord-006870-f5w6fw6q 3320 12 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 3320 13 mechanisms mechanism NNS cord-006870-f5w6fw6q 3320 14 . . . cord-006870-f5w6fw6q 3321 1 Current current JJ cord-006870-f5w6fw6q 3321 2 imaging imaging NN cord-006870-f5w6fw6q 3321 3 modalities modality NNS cord-006870-f5w6fw6q 3321 4 , , , cord-006870-f5w6fw6q 3321 5 specifically specifically RB cord-006870-f5w6fw6q 3321 6 magnetic magnetic JJ cord-006870-f5w6fw6q 3321 7 resonance resonance NN cord-006870-f5w6fw6q 3321 8 imaging imaging NN cord-006870-f5w6fw6q 3321 9 allow allow VBP cord-006870-f5w6fw6q 3321 10 for for IN cord-006870-f5w6fw6q 3321 11 easier easy JJR cord-006870-f5w6fw6q 3321 12 detection detection NN cord-006870-f5w6fw6q 3321 13 of of IN cord-006870-f5w6fw6q 3321 14 different different JJ cord-006870-f5w6fw6q 3321 15 intracranial intracranial JJ cord-006870-f5w6fw6q 3321 16 pathological pathological JJ cord-006870-f5w6fw6q 3321 17 processes process NNS cord-006870-f5w6fw6q 3321 18 including include VBG cord-006870-f5w6fw6q 3321 19 cerebral cerebral JJ cord-006870-f5w6fw6q 3321 20 microhemorrhages microhemorrhage NNS cord-006870-f5w6fw6q 3321 21 ( ( -LRB- cord-006870-f5w6fw6q 3321 22 CMs CMs NNP cord-006870-f5w6fw6q 3321 23 ) ) -RRB- cord-006870-f5w6fw6q 3321 24 . . . cord-006870-f5w6fw6q 3322 1 Research research NN cord-006870-f5w6fw6q 3322 2 demonstrated demonstrate VBD cord-006870-f5w6fw6q 3322 3 that that IN cord-006870-f5w6fw6q 3322 4 the the DT cord-006870-f5w6fw6q 3322 5 number number NN cord-006870-f5w6fw6q 3322 6 and and CC cord-006870-f5w6fw6q 3322 7 location location NN cord-006870-f5w6fw6q 3322 8 of of IN cord-006870-f5w6fw6q 3322 9 CMs CMs NNP cord-006870-f5w6fw6q 3322 10 correlate correlate VB cord-006870-f5w6fw6q 3322 11 with with IN cord-006870-f5w6fw6q 3322 12 the the DT cord-006870-f5w6fw6q 3322 13 type type NN cord-006870-f5w6fw6q 3322 14 of of IN cord-006870-f5w6fw6q 3322 15 cognitive cognitive JJ cord-006870-f5w6fw6q 3322 16 impairment impairment NN cord-006870-f5w6fw6q 3322 17 ( ( -LRB- cord-006870-f5w6fw6q 3322 18 memory memory NN cord-006870-f5w6fw6q 3322 19 , , , cord-006870-f5w6fw6q 3322 20 processing processing NN cord-006870-f5w6fw6q 3322 21 speed speed NN cord-006870-f5w6fw6q 3322 22 , , , cord-006870-f5w6fw6q 3322 23 executive executive JJ cord-006870-f5w6fw6q 3322 24 function function NN cord-006870-f5w6fw6q 3322 25 , , , cord-006870-f5w6fw6q 3322 26 and and CC cord-006870-f5w6fw6q 3322 27 motor motor NN cord-006870-f5w6fw6q 3322 28 speed speed NN cord-006870-f5w6fw6q 3322 29 ) ) -RRB- cord-006870-f5w6fw6q 3322 30 . . . cord-006870-f5w6fw6q 3323 1 A a DT cord-006870-f5w6fw6q 3323 2 retrospective retrospective JJ cord-006870-f5w6fw6q 3323 3 analysis analysis NN cord-006870-f5w6fw6q 3323 4 of of IN cord-006870-f5w6fw6q 3323 5 50 50 CD cord-006870-f5w6fw6q 3323 6 patients patient NNS cord-006870-f5w6fw6q 3323 7 ( ( -LRB- cord-006870-f5w6fw6q 3323 8 age age NN cord-006870-f5w6fw6q 3323 9 44 44 CD cord-006870-f5w6fw6q 3323 10 to to IN cord-006870-f5w6fw6q 3323 11 87 87 CD cord-006870-f5w6fw6q 3323 12 ) ) -RRB- cord-006870-f5w6fw6q 3323 13 seen see VBN cord-006870-f5w6fw6q 3323 14 at at IN cord-006870-f5w6fw6q 3323 15 our -PRON- PRP$ cord-006870-f5w6fw6q 3323 16 neurology neurology NN cord-006870-f5w6fw6q 3323 17 outpatient outpatient NN cord-006870-f5w6fw6q 3323 18 clinic clinic NN cord-006870-f5w6fw6q 3323 19 from from IN cord-006870-f5w6fw6q 3323 20 2010 2010 CD cord-006870-f5w6fw6q 3323 21 to to IN cord-006870-f5w6fw6q 3323 22 2017 2017 CD cord-006870-f5w6fw6q 3323 23 who who WP cord-006870-f5w6fw6q 3323 24 were be VBD cord-006870-f5w6fw6q 3323 25 identified identify VBN cord-006870-f5w6fw6q 3323 26 by by IN cord-006870-f5w6fw6q 3323 27 Linguamatics Linguamatics NNP cord-006870-f5w6fw6q 3323 28 software software NN cord-006870-f5w6fw6q 3323 29 to to TO cord-006870-f5w6fw6q 3323 30 have have VB cord-006870-f5w6fw6q 3323 31 " " `` cord-006870-f5w6fw6q 3323 32 microhemorrhage microhemorrhage NN cord-006870-f5w6fw6q 3323 33 " " '' cord-006870-f5w6fw6q 3323 34 in in IN cord-006870-f5w6fw6q 3323 35 their -PRON- PRP$ cord-006870-f5w6fw6q 3323 36 radiology radiology NN cord-006870-f5w6fw6q 3323 37 MRI MRI NNP cord-006870-f5w6fw6q 3323 38 report report NN cord-006870-f5w6fw6q 3323 39 . . . cord-006870-f5w6fw6q 3324 1 Additional additional JJ cord-006870-f5w6fw6q 3324 2 information information NN cord-006870-f5w6fw6q 3324 3 included include VBD cord-006870-f5w6fw6q 3324 4 age age NN cord-006870-f5w6fw6q 3324 5 , , , cord-006870-f5w6fw6q 3324 6 sex sex NN cord-006870-f5w6fw6q 3324 7 , , , cord-006870-f5w6fw6q 3324 8 cognitive cognitive JJ cord-006870-f5w6fw6q 3324 9 examination examination NN cord-006870-f5w6fw6q 3324 10 , , , cord-006870-f5w6fw6q 3324 11 presence presence NN cord-006870-f5w6fw6q 3324 12 of of IN cord-006870-f5w6fw6q 3324 13 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 3324 14 risk risk NN cord-006870-f5w6fw6q 3324 15 factors factor NNS cord-006870-f5w6fw6q 3324 16 , , , cord-006870-f5w6fw6q 3324 17 MRI MRI NNP cord-006870-f5w6fw6q 3324 18 , , , cord-006870-f5w6fw6q 3324 19 and and CC cord-006870-f5w6fw6q 3324 20 the the DT cord-006870-f5w6fw6q 3324 21 number number NN cord-006870-f5w6fw6q 3324 22 and and CC cord-006870-f5w6fw6q 3324 23 location location NN cord-006870-f5w6fw6q 3324 24 of of IN cord-006870-f5w6fw6q 3324 25 CMs CMs NNP cord-006870-f5w6fw6q 3324 26 . . . cord-006870-f5w6fw6q 3325 1 Cognitive cognitive JJ cord-006870-f5w6fw6q 3325 2 function function NN cord-006870-f5w6fw6q 3325 3 was be VBD cord-006870-f5w6fw6q 3325 4 determined determine VBN cord-006870-f5w6fw6q 3325 5 by by IN cord-006870-f5w6fw6q 3325 6 Mini Mini NNP cord-006870-f5w6fw6q 3325 7 Mental Mental NNP cord-006870-f5w6fw6q 3325 8 State State NNP cord-006870-f5w6fw6q 3325 9 Examination Examination NNP cord-006870-f5w6fw6q 3325 10 ( ( -LRB- cord-006870-f5w6fw6q 3325 11 MMSE MMSE NNP cord-006870-f5w6fw6q 3325 12 ) ) -RRB- cord-006870-f5w6fw6q 3325 13 score score NN cord-006870-f5w6fw6q 3325 14 and and CC cord-006870-f5w6fw6q 3325 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 3325 16 by by IN cord-006870-f5w6fw6q 3325 17 a a DT cord-006870-f5w6fw6q 3325 18 cognitive cognitive JJ cord-006870-f5w6fw6q 3325 19 neurologist neurologist NN cord-006870-f5w6fw6q 3325 20 . . . cord-006870-f5w6fw6q 3326 1 Patients patient NNS cord-006870-f5w6fw6q 3326 2 were be VBD cord-006870-f5w6fw6q 3326 3 grouped group VBN cord-006870-f5w6fw6q 3326 4 by by IN cord-006870-f5w6fw6q 3326 5 presence presence NN cord-006870-f5w6fw6q 3326 6 of of IN cord-006870-f5w6fw6q 3326 7 1 1 CD cord-006870-f5w6fw6q 3326 8 CM cm NN cord-006870-f5w6fw6q 3326 9 or or CC cord-006870-f5w6fw6q 3326 10 greater great JJR cord-006870-f5w6fw6q 3326 11 ( ( -LRB- cord-006870-f5w6fw6q 3326 12 2 2 CD cord-006870-f5w6fw6q 3326 13 to to IN cord-006870-f5w6fw6q 3326 14 10 10 CD cord-006870-f5w6fw6q 3326 15 ) ) -RRB- cord-006870-f5w6fw6q 3326 16 and and CC cord-006870-f5w6fw6q 3326 17 regression regression NN cord-006870-f5w6fw6q 3326 18 was be VBD cord-006870-f5w6fw6q 3326 19 used use VBN cord-006870-f5w6fw6q 3326 20 to to TO cord-006870-f5w6fw6q 3326 21 determine determine VB cord-006870-f5w6fw6q 3326 22 a a DT cord-006870-f5w6fw6q 3326 23 relationship relationship NN cord-006870-f5w6fw6q 3326 24 with with IN cord-006870-f5w6fw6q 3326 25 MMSE MMSE NNP cord-006870-f5w6fw6q 3326 26 and and CC cord-006870-f5w6fw6q 3326 27 vascular vascular JJ cord-006870-f5w6fw6q 3326 28 risk risk NN cord-006870-f5w6fw6q 3326 29 factors factor NNS cord-006870-f5w6fw6q 3326 30 . . . cord-006870-f5w6fw6q 3327 1 The the DT cord-006870-f5w6fw6q 3327 2 number number NN cord-006870-f5w6fw6q 3327 3 of of IN cord-006870-f5w6fw6q 3327 4 microhemorrhages microhemorrhage NNS cord-006870-f5w6fw6q 3327 5 per per IN cord-006870-f5w6fw6q 3327 6 patient patient NN cord-006870-f5w6fw6q 3327 7 were be VBD cord-006870-f5w6fw6q 3327 8 1(17 1(17 JJ cord-006870-f5w6fw6q 3327 9 patients patient NNS cord-006870-f5w6fw6q 3327 10 ) ) -RRB- cord-006870-f5w6fw6q 3327 11 , , , cord-006870-f5w6fw6q 3327 12 2 2 CD cord-006870-f5w6fw6q 3327 13 ( ( -LRB- cord-006870-f5w6fw6q 3327 14 5 5 CD cord-006870-f5w6fw6q 3327 15 patients patient NNS cord-006870-f5w6fw6q 3327 16 ) ) -RRB- cord-006870-f5w6fw6q 3327 17 , , , cord-006870-f5w6fw6q 3327 18 3 3 CD cord-006870-f5w6fw6q 3327 19 ( ( -LRB- cord-006870-f5w6fw6q 3327 20 8 8 CD cord-006870-f5w6fw6q 3327 21 patients patient NNS cord-006870-f5w6fw6q 3327 22 ) ) -RRB- cord-006870-f5w6fw6q 3327 23 , , , cord-006870-f5w6fw6q 3327 24 4 4 CD cord-006870-f5w6fw6q 3327 25 ( ( -LRB- cord-006870-f5w6fw6q 3327 26 12 12 CD cord-006870-f5w6fw6q 3327 27 patients patient NNS cord-006870-f5w6fw6q 3327 28 ) ) -RRB- cord-006870-f5w6fw6q 3327 29 , , , cord-006870-f5w6fw6q 3327 30 5 5 CD cord-006870-f5w6fw6q 3327 31 ( ( -LRB- cord-006870-f5w6fw6q 3327 32 3 3 CD cord-006870-f5w6fw6q 3327 33 patients patient NNS cord-006870-f5w6fw6q 3327 34 ) ) -RRB- cord-006870-f5w6fw6q 3327 35 , , , cord-006870-f5w6fw6q 3327 36 6 6 CD cord-006870-f5w6fw6q 3327 37 ( ( -LRB- cord-006870-f5w6fw6q 3327 38 3 3 CD cord-006870-f5w6fw6q 3327 39 patients patient NNS cord-006870-f5w6fw6q 3327 40 ) ) -RRB- cord-006870-f5w6fw6q 3327 41 and and CC cord-006870-f5w6fw6q 3327 42 10 10 CD cord-006870-f5w6fw6q 3327 43 ( ( -LRB- cord-006870-f5w6fw6q 3327 44 2 2 CD cord-006870-f5w6fw6q 3327 45 patients patient NNS cord-006870-f5w6fw6q 3327 46 ) ) -RRB- cord-006870-f5w6fw6q 3327 47 . . . cord-006870-f5w6fw6q 3328 1 Vascular vascular JJ cord-006870-f5w6fw6q 3328 2 risk risk NN cord-006870-f5w6fw6q 3328 3 factors factor NNS cord-006870-f5w6fw6q 3328 4 included include VBD cord-006870-f5w6fw6q 3328 5 hypertension hypertension NN cord-006870-f5w6fw6q 3328 6 ( ( -LRB- cord-006870-f5w6fw6q 3328 7 16 16 CD cord-006870-f5w6fw6q 3328 8 patients patient NNS cord-006870-f5w6fw6q 3328 9 ) ) -RRB- cord-006870-f5w6fw6q 3328 10 , , , cord-006870-f5w6fw6q 3328 11 diabetes diabete VBZ cord-006870-f5w6fw6q 3328 12 mellitus mellitus NN cord-006870-f5w6fw6q 3328 13 ( ( -LRB- cord-006870-f5w6fw6q 3328 14 25 25 CD cord-006870-f5w6fw6q 3328 15 patients patient NNS cord-006870-f5w6fw6q 3328 16 ) ) -RRB- cord-006870-f5w6fw6q 3328 17 and and CC cord-006870-f5w6fw6q 3328 18 smoking smoke VBG cord-006870-f5w6fw6q 3328 19 history history NN cord-006870-f5w6fw6q 3328 20 ( ( -LRB- cord-006870-f5w6fw6q 3328 21 26 26 CD cord-006870-f5w6fw6q 3328 22 patients patient NNS cord-006870-f5w6fw6q 3328 23 ) ) -RRB- cord-006870-f5w6fw6q 3328 24 . . . cord-006870-f5w6fw6q 3329 1 Regression regression NN cord-006870-f5w6fw6q 3329 2 analyses analysis NNS cord-006870-f5w6fw6q 3329 3 indicated indicate VBD cord-006870-f5w6fw6q 3329 4 that that IN cord-006870-f5w6fw6q 3329 5 the the DT cord-006870-f5w6fw6q 3329 6 presence presence NN cord-006870-f5w6fw6q 3329 7 of of IN cord-006870-f5w6fw6q 3329 8 more more JJR cord-006870-f5w6fw6q 3329 9 than than IN cord-006870-f5w6fw6q 3329 10 1 1 CD cord-006870-f5w6fw6q 3329 11 CM cm NN cord-006870-f5w6fw6q 3329 12 correctly correctly RB cord-006870-f5w6fw6q 3329 13 predicted predict VBD cord-006870-f5w6fw6q 3329 14 MMSE MMSE NNP cord-006870-f5w6fw6q 3329 15 lower low JJR cord-006870-f5w6fw6q 3329 16 than than IN cord-006870-f5w6fw6q 3329 17 26 26 CD cord-006870-f5w6fw6q 3329 18 at at IN cord-006870-f5w6fw6q 3329 19 83 83 CD cord-006870-f5w6fw6q 3329 20 % % NN cord-006870-f5w6fw6q 3329 21 ( ( -LRB- cord-006870-f5w6fw6q 3329 22 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 3329 23 ) ) -RRB- cord-006870-f5w6fw6q 3329 24 . . . cord-006870-f5w6fw6q 3330 1 Age age NN cord-006870-f5w6fw6q 3330 2 was be VBD cord-006870-f5w6fw6q 3330 3 the the DT cord-006870-f5w6fw6q 3330 4 only only JJ cord-006870-f5w6fw6q 3330 5 factor factor NN cord-006870-f5w6fw6q 3330 6 that that WDT cord-006870-f5w6fw6q 3330 7 influences influence VBZ cord-006870-f5w6fw6q 3330 8 this this DT cord-006870-f5w6fw6q 3330 9 finding finding NN cord-006870-f5w6fw6q 3330 10 and and CC cord-006870-f5w6fw6q 3330 11 increased increase VBD cord-006870-f5w6fw6q 3330 12 this this DT cord-006870-f5w6fw6q 3330 13 prediction prediction NN cord-006870-f5w6fw6q 3330 14 to to IN cord-006870-f5w6fw6q 3330 15 90 90 CD cord-006870-f5w6fw6q 3330 16 % % NN cord-006870-f5w6fw6q 3330 17 . . . cord-006870-f5w6fw6q 3331 1 This this DT cord-006870-f5w6fw6q 3331 2 study study NN cord-006870-f5w6fw6q 3331 3 provides provide VBZ cord-006870-f5w6fw6q 3331 4 novel novel JJ cord-006870-f5w6fw6q 3331 5 evidence evidence NN cord-006870-f5w6fw6q 3331 6 that that IN cord-006870-f5w6fw6q 3331 7 the the DT cord-006870-f5w6fw6q 3331 8 presence presence NN cord-006870-f5w6fw6q 3331 9 of of IN cord-006870-f5w6fw6q 3331 10 multiple multiple JJ cord-006870-f5w6fw6q 3331 11 CMs cms NN cord-006870-f5w6fw6q 3331 12 on on IN cord-006870-f5w6fw6q 3331 13 brain brain NN cord-006870-f5w6fw6q 3331 14 images image NNS cord-006870-f5w6fw6q 3331 15 predicts predict VBZ cord-006870-f5w6fw6q 3331 16 the the DT cord-006870-f5w6fw6q 3331 17 presence presence NN cord-006870-f5w6fw6q 3331 18 of of IN cord-006870-f5w6fw6q 3331 19 cognitive cognitive JJ cord-006870-f5w6fw6q 3331 20 impairment impairment NN cord-006870-f5w6fw6q 3331 21 . . . cord-006870-f5w6fw6q 3332 1 This this DT cord-006870-f5w6fw6q 3332 2 study study NN cord-006870-f5w6fw6q 3332 3 raises raise VBZ cord-006870-f5w6fw6q 3332 4 the the DT cord-006870-f5w6fw6q 3332 5 need need NN cord-006870-f5w6fw6q 3332 6 for for IN cord-006870-f5w6fw6q 3332 7 more more JJR cord-006870-f5w6fw6q 3332 8 investigations investigation NNS cord-006870-f5w6fw6q 3332 9 . . . cord-006870-f5w6fw6q 3333 1 Point point NN cord-006870-f5w6fw6q 3333 2 - - HYPH cord-006870-f5w6fw6q 3333 3 of of IN cord-006870-f5w6fw6q 3333 4 - - HYPH cord-006870-f5w6fw6q 3333 5 care care NN cord-006870-f5w6fw6q 3333 6 ultrasound ultrasound NN cord-006870-f5w6fw6q 3333 7 is be VBZ cord-006870-f5w6fw6q 3333 8 a a DT cord-006870-f5w6fw6q 3333 9 valuable valuable JJ cord-006870-f5w6fw6q 3333 10 tool tool NN cord-006870-f5w6fw6q 3333 11 in in IN cord-006870-f5w6fw6q 3333 12 critical critical JJ cord-006870-f5w6fw6q 3333 13 care care NN cord-006870-f5w6fw6q 3333 14 , , , cord-006870-f5w6fw6q 3333 15 allowing allow VBG cord-006870-f5w6fw6q 3333 16 timely timely JJ cord-006870-f5w6fw6q 3333 17 and and CC cord-006870-f5w6fw6q 3333 18 frequent frequent JJ cord-006870-f5w6fw6q 3333 19 beside beside IN cord-006870-f5w6fw6q 3333 20 assessment assessment NN cord-006870-f5w6fw6q 3333 21 of of IN cord-006870-f5w6fw6q 3333 22 clinical clinical JJ cord-006870-f5w6fw6q 3333 23 questions question NNS cord-006870-f5w6fw6q 3333 24 . . . cord-006870-f5w6fw6q 3334 1 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3334 2 care care NN cord-006870-f5w6fw6q 3334 3 has have VBZ cord-006870-f5w6fw6q 3334 4 long long RB cord-006870-f5w6fw6q 3334 5 utilized utilize VBN cord-006870-f5w6fw6q 3334 6 transcranial transcranial JJ cord-006870-f5w6fw6q 3334 7 Doppler doppler NN cord-006870-f5w6fw6q 3334 8 but but CC cord-006870-f5w6fw6q 3334 9 is be VBZ cord-006870-f5w6fw6q 3334 10 still still RB cord-006870-f5w6fw6q 3334 11 early early JJ cord-006870-f5w6fw6q 3334 12 in in IN cord-006870-f5w6fw6q 3334 13 the the DT cord-006870-f5w6fw6q 3334 14 adoption adoption NN cord-006870-f5w6fw6q 3334 15 of of IN cord-006870-f5w6fw6q 3334 16 other other JJ cord-006870-f5w6fw6q 3334 17 critical critical JJ cord-006870-f5w6fw6q 3334 18 care care NN cord-006870-f5w6fw6q 3334 19 ultrasounds ultrasound NNS cord-006870-f5w6fw6q 3334 20 . . . cord-006870-f5w6fw6q 3335 1 This this DT cord-006870-f5w6fw6q 3335 2 study study NN cord-006870-f5w6fw6q 3335 3 looked look VBD cord-006870-f5w6fw6q 3335 4 at at IN cord-006870-f5w6fw6q 3335 5 the the DT cord-006870-f5w6fw6q 3335 6 comfort comfort NN cord-006870-f5w6fw6q 3335 7 level level NN cord-006870-f5w6fw6q 3335 8 and and CC cord-006870-f5w6fw6q 3335 9 competency competency NN cord-006870-f5w6fw6q 3335 10 of of IN cord-006870-f5w6fw6q 3335 11 the the DT cord-006870-f5w6fw6q 3335 12 participants participant NNS cord-006870-f5w6fw6q 3335 13 at at IN cord-006870-f5w6fw6q 3335 14 the the DT cord-006870-f5w6fw6q 3335 15 point point NN cord-006870-f5w6fw6q 3335 16 - - HYPH cord-006870-f5w6fw6q 3335 17 of of IN cord-006870-f5w6fw6q 3335 18 - - HYPH cord-006870-f5w6fw6q 3335 19 care care NN cord-006870-f5w6fw6q 3335 20 ultrasound ultrasound NN cord-006870-f5w6fw6q 3335 21 workshop workshop NN cord-006870-f5w6fw6q 3335 22 at at IN cord-006870-f5w6fw6q 3335 23 the the DT cord-006870-f5w6fw6q 3335 24 2016 2016 CD cord-006870-f5w6fw6q 3335 25 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3335 26 Care Care NNP cord-006870-f5w6fw6q 3335 27 Society Society NNP cord-006870-f5w6fw6q 3335 28 Annual Annual NNP cord-006870-f5w6fw6q 3335 29 Meeting Meeting NNP cord-006870-f5w6fw6q 3335 30 . . . cord-006870-f5w6fw6q 3336 1 The the DT cord-006870-f5w6fw6q 3336 2 workshop workshop NN cord-006870-f5w6fw6q 3336 3 comprised comprise VBN cord-006870-f5w6fw6q 3336 4 of of IN cord-006870-f5w6fw6q 3336 5 didactics didactic NNS cord-006870-f5w6fw6q 3336 6 and and CC cord-006870-f5w6fw6q 3336 7 hands hand NNS cord-006870-f5w6fw6q 3336 8 - - HYPH cord-006870-f5w6fw6q 3336 9 on on RP cord-006870-f5w6fw6q 3336 10 small small JJ cord-006870-f5w6fw6q 3336 11 group group NN cord-006870-f5w6fw6q 3336 12 practice practice NN cord-006870-f5w6fw6q 3336 13 using use VBG cord-006870-f5w6fw6q 3336 14 live live JJ cord-006870-f5w6fw6q 3336 15 models model NNS cord-006870-f5w6fw6q 3336 16 . . . cord-006870-f5w6fw6q 3337 1 Topics topic NNS cord-006870-f5w6fw6q 3337 2 covered cover VBN cord-006870-f5w6fw6q 3337 3 included include VBD cord-006870-f5w6fw6q 3337 4 ultrasound ultrasound NN cord-006870-f5w6fw6q 3337 5 physics physics NN cord-006870-f5w6fw6q 3337 6 , , , cord-006870-f5w6fw6q 3337 7 lung lung NN cord-006870-f5w6fw6q 3337 8 , , , cord-006870-f5w6fw6q 3337 9 cardiac cardiac NN cord-006870-f5w6fw6q 3337 10 , , , cord-006870-f5w6fw6q 3337 11 optic optic JJ cord-006870-f5w6fw6q 3337 12 nerve nerve NN cord-006870-f5w6fw6q 3337 13 sheath sheath NN cord-006870-f5w6fw6q 3337 14 ultrasounds ultrasound NNS cord-006870-f5w6fw6q 3337 15 , , , cord-006870-f5w6fw6q 3337 16 as as RB cord-006870-f5w6fw6q 3337 17 well well RB cord-006870-f5w6fw6q 3337 18 as as IN cord-006870-f5w6fw6q 3337 19 case case NN cord-006870-f5w6fw6q 3337 20 studies study NNS cord-006870-f5w6fw6q 3337 21 in in IN cord-006870-f5w6fw6q 3337 22 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3337 23 care care NN cord-006870-f5w6fw6q 3337 24 . . . cord-006870-f5w6fw6q 3338 1 Participants participant NNS cord-006870-f5w6fw6q 3338 2 were be VBD cord-006870-f5w6fw6q 3338 3 asked ask VBN cord-006870-f5w6fw6q 3338 4 to to TO cord-006870-f5w6fw6q 3338 5 complete complete VB cord-006870-f5w6fw6q 3338 6 an an DT cord-006870-f5w6fw6q 3338 7 anonymous anonymous JJ cord-006870-f5w6fw6q 3338 8 pre pre JJ cord-006870-f5w6fw6q 3338 9 - - JJ cord-006870-f5w6fw6q 3338 10 and and CC cord-006870-f5w6fw6q 3338 11 postworkshop postworkshop NN cord-006870-f5w6fw6q 3338 12 assessment assessment NN cord-006870-f5w6fw6q 3338 13 on on IN cord-006870-f5w6fw6q 3338 14 a a DT cord-006870-f5w6fw6q 3338 15 volunteer volunteer NN cord-006870-f5w6fw6q 3338 16 basis basis NN cord-006870-f5w6fw6q 3338 17 . . . cord-006870-f5w6fw6q 3339 1 A a DT cord-006870-f5w6fw6q 3339 2 total total JJ cord-006870-f5w6fw6q 3339 3 41 41 CD cord-006870-f5w6fw6q 3339 4 pre pre JJ cord-006870-f5w6fw6q 3339 5 - - JJ cord-006870-f5w6fw6q 3339 6 workshop workshop NN cord-006870-f5w6fw6q 3339 7 and and CC cord-006870-f5w6fw6q 3339 8 33 33 CD cord-006870-f5w6fw6q 3339 9 post post JJ cord-006870-f5w6fw6q 3339 10 - - JJ cord-006870-f5w6fw6q 3339 11 workshop workshop JJ cord-006870-f5w6fw6q 3339 12 assessments assessment NNS cord-006870-f5w6fw6q 3339 13 were be VBD cord-006870-f5w6fw6q 3339 14 completed complete VBN cord-006870-f5w6fw6q 3339 15 . . . cord-006870-f5w6fw6q 3340 1 The the DT cord-006870-f5w6fw6q 3340 2 mean mean JJ cord-006870-f5w6fw6q 3340 3 age age NN cord-006870-f5w6fw6q 3340 4 of of IN cord-006870-f5w6fw6q 3340 5 the the DT cord-006870-f5w6fw6q 3340 6 participants participant NNS cord-006870-f5w6fw6q 3340 7 was be VBD cord-006870-f5w6fw6q 3340 8 40.7 40.7 CD cord-006870-f5w6fw6q 3340 9 ± ± CD cord-006870-f5w6fw6q 3340 10 9.2 9.2 CD cord-006870-f5w6fw6q 3340 11 years year NNS cord-006870-f5w6fw6q 3340 12 . . . cord-006870-f5w6fw6q 3341 1 There there EX cord-006870-f5w6fw6q 3341 2 were be VBD cord-006870-f5w6fw6q 3341 3 21 21 CD cord-006870-f5w6fw6q 3341 4 ( ( -LRB- cord-006870-f5w6fw6q 3341 5 51.2 51.2 CD cord-006870-f5w6fw6q 3341 6 % % NN cord-006870-f5w6fw6q 3341 7 ) ) -RRB- cord-006870-f5w6fw6q 3341 8 attending attend VBG cord-006870-f5w6fw6q 3341 9 physicians physician NNS cord-006870-f5w6fw6q 3341 10 , , , cord-006870-f5w6fw6q 3341 11 8 8 CD cord-006870-f5w6fw6q 3341 12 ( ( -LRB- cord-006870-f5w6fw6q 3341 13 19.5 19.5 CD cord-006870-f5w6fw6q 3341 14 % % NN cord-006870-f5w6fw6q 3341 15 ) ) -RRB- cord-006870-f5w6fw6q 3341 16 advance advance NN cord-006870-f5w6fw6q 3341 17 practice practice NN cord-006870-f5w6fw6q 3341 18 practitioners practitioner NNS cord-006870-f5w6fw6q 3341 19 , , , cord-006870-f5w6fw6q 3341 20 7 7 CD cord-006870-f5w6fw6q 3341 21 ( ( -LRB- cord-006870-f5w6fw6q 3341 22 17.0 17.0 CD cord-006870-f5w6fw6q 3341 23 % % NN cord-006870-f5w6fw6q 3341 24 ) ) -RRB- cord-006870-f5w6fw6q 3341 25 fellows fellow NNS cord-006870-f5w6fw6q 3341 26 , , , cord-006870-f5w6fw6q 3341 27 4 4 CD cord-006870-f5w6fw6q 3341 28 ( ( -LRB- cord-006870-f5w6fw6q 3341 29 9.7 9.7 CD cord-006870-f5w6fw6q 3341 30 % % NN cord-006870-f5w6fw6q 3341 31 ) ) -RRB- cord-006870-f5w6fw6q 3341 32 residents resident NNS cord-006870-f5w6fw6q 3341 33 , , , cord-006870-f5w6fw6q 3341 34 and and CC cord-006870-f5w6fw6q 3341 35 1 1 CD cord-006870-f5w6fw6q 3341 36 ( ( -LRB- cord-006870-f5w6fw6q 3341 37 2.4 2.4 CD cord-006870-f5w6fw6q 3341 38 % % NN cord-006870-f5w6fw6q 3341 39 ) ) -RRB- cord-006870-f5w6fw6q 3341 40 research research NN cord-006870-f5w6fw6q 3341 41 scientist scientist NN cord-006870-f5w6fw6q 3341 42 . . . cord-006870-f5w6fw6q 3342 1 Participants participant NNS cord-006870-f5w6fw6q 3342 2 had have VBD cord-006870-f5w6fw6q 3342 3 limited limit VBN cord-006870-f5w6fw6q 3342 4 ultrasound ultrasound NN cord-006870-f5w6fw6q 3342 5 experience experience NN cord-006870-f5w6fw6q 3342 6 prior prior RB cord-006870-f5w6fw6q 3342 7 to to IN cord-006870-f5w6fw6q 3342 8 the the DT cord-006870-f5w6fw6q 3342 9 workshop workshop NN cord-006870-f5w6fw6q 3342 10 , , , cord-006870-f5w6fw6q 3342 11 with with IN cord-006870-f5w6fw6q 3342 12 12 12 CD cord-006870-f5w6fw6q 3342 13 ( ( -LRB- cord-006870-f5w6fw6q 3342 14 29.2 29.2 CD cord-006870-f5w6fw6q 3342 15 % % NN cord-006870-f5w6fw6q 3342 16 ) ) -RRB- cord-006870-f5w6fw6q 3342 17 reported report VBD cord-006870-f5w6fw6q 3342 18 none none NN cord-006870-f5w6fw6q 3342 19 , , , cord-006870-f5w6fw6q 3342 20 16 16 CD cord-006870-f5w6fw6q 3342 21 ( ( -LRB- cord-006870-f5w6fw6q 3342 22 39.0 39.0 CD cord-006870-f5w6fw6q 3342 23 % % NN cord-006870-f5w6fw6q 3342 24 ) ) -RRB- cord-006870-f5w6fw6q 3342 25 reported report VBD cord-006870-f5w6fw6q 3342 26 < < NNP cord-006870-f5w6fw6q 3342 27 1 1 CD cord-006870-f5w6fw6q 3342 28 year year NN cord-006870-f5w6fw6q 3342 29 , , , cord-006870-f5w6fw6q 3342 30 and and CC cord-006870-f5w6fw6q 3342 31 10 10 CD cord-006870-f5w6fw6q 3342 32 ( ( -LRB- cord-006870-f5w6fw6q 3342 33 24.3 24.3 CD cord-006870-f5w6fw6q 3342 34 % % NN cord-006870-f5w6fw6q 3342 35 ) ) -RRB- cord-006870-f5w6fw6q 3342 36 reported report VBD cord-006870-f5w6fw6q 3342 37 1 1 CD cord-006870-f5w6fw6q 3342 38 to to IN cord-006870-f5w6fw6q 3342 39 3 3 CD cord-006870-f5w6fw6q 3342 40 years year NNS cord-006870-f5w6fw6q 3342 41 . . . cord-006870-f5w6fw6q 3343 1 On on IN cord-006870-f5w6fw6q 3343 2 a a DT cord-006870-f5w6fw6q 3343 3 1 1 CD cord-006870-f5w6fw6q 3343 4 - - SYM cord-006870-f5w6fw6q 3343 5 5 5 CD cord-006870-f5w6fw6q 3343 6 scale scale NN cord-006870-f5w6fw6q 3343 7 on on IN cord-006870-f5w6fw6q 3343 8 comfort comfort NN cord-006870-f5w6fw6q 3343 9 using use VBG cord-006870-f5w6fw6q 3343 10 ultrasound ultrasound NN cord-006870-f5w6fw6q 3343 11 with with IN cord-006870-f5w6fw6q 3343 12 1 1 CD cord-006870-f5w6fw6q 3343 13 being be VBG cord-006870-f5w6fw6q 3343 14 very very RB cord-006870-f5w6fw6q 3343 15 uncomfortable uncomfortable JJ cord-006870-f5w6fw6q 3343 16 and and CC cord-006870-f5w6fw6q 3343 17 5 5 CD cord-006870-f5w6fw6q 3343 18 being be VBG cord-006870-f5w6fw6q 3343 19 very very RB cord-006870-f5w6fw6q 3343 20 comfortable comfortable JJ cord-006870-f5w6fw6q 3343 21 , , , cord-006870-f5w6fw6q 3343 22 participants participant NNS cord-006870-f5w6fw6q 3343 23 reported report VBD cord-006870-f5w6fw6q 3343 24 a a DT cord-006870-f5w6fw6q 3343 25 median median JJ cord-006870-f5w6fw6q 3343 26 score score NN cord-006870-f5w6fw6q 3343 27 of of IN cord-006870-f5w6fw6q 3343 28 2 2 CD cord-006870-f5w6fw6q 3343 29 ( ( -LRB- cord-006870-f5w6fw6q 3343 30 IQR IQR NNP cord-006870-f5w6fw6q 3343 31 2 2 CD cord-006870-f5w6fw6q 3343 32 - - SYM cord-006870-f5w6fw6q 3343 33 3 3 CD cord-006870-f5w6fw6q 3343 34 ) ) -RRB- cord-006870-f5w6fw6q 3343 35 pre pre JJ cord-006870-f5w6fw6q 3343 36 - - VB cord-006870-f5w6fw6q 3343 37 workshop workshop NN cord-006870-f5w6fw6q 3343 38 with with IN cord-006870-f5w6fw6q 3343 39 an an DT cord-006870-f5w6fw6q 3343 40 improvement improvement NN cord-006870-f5w6fw6q 3343 41 to to IN cord-006870-f5w6fw6q 3343 42 4 4 CD cord-006870-f5w6fw6q 3343 43 ( ( -LRB- cord-006870-f5w6fw6q 3343 44 IQR IQR NNP cord-006870-f5w6fw6q 3343 45 3 3 CD cord-006870-f5w6fw6q 3343 46 - - SYM cord-006870-f5w6fw6q 3343 47 4 4 CD cord-006870-f5w6fw6q 3343 48 ) ) -RRB- cord-006870-f5w6fw6q 3343 49 post post JJ cord-006870-f5w6fw6q 3343 50 - - NN cord-006870-f5w6fw6q 3343 51 workshop workshop NN cord-006870-f5w6fw6q 3343 52 . . . cord-006870-f5w6fw6q 3344 1 For for IN cord-006870-f5w6fw6q 3344 2 15 15 CD cord-006870-f5w6fw6q 3344 3 matched match VBN cord-006870-f5w6fw6q 3344 4 pre pre JJ cord-006870-f5w6fw6q 3344 5 - - JJ cord-006870-f5w6fw6q 3344 6 and and CC cord-006870-f5w6fw6q 3344 7 post post NN cord-006870-f5w6fw6q 3344 8 - - NNS cord-006870-f5w6fw6q 3344 9 tests test NNS cord-006870-f5w6fw6q 3344 10 , , , cord-006870-f5w6fw6q 3344 11 all all DT cord-006870-f5w6fw6q 3344 12 15 15 CD cord-006870-f5w6fw6q 3344 13 participants participant NNS cord-006870-f5w6fw6q 3344 14 had have VBD cord-006870-f5w6fw6q 3344 15 an an DT cord-006870-f5w6fw6q 3344 16 improvement improvement NN cord-006870-f5w6fw6q 3344 17 in in IN cord-006870-f5w6fw6q 3344 18 their -PRON- PRP$ cord-006870-f5w6fw6q 3344 19 ultrasound ultrasound NN cord-006870-f5w6fw6q 3344 20 knowledge knowledge NN cord-006870-f5w6fw6q 3344 21 . . . cord-006870-f5w6fw6q 3345 1 While while IN cord-006870-f5w6fw6q 3345 2 the the DT cord-006870-f5w6fw6q 3345 3 majority majority NN cord-006870-f5w6fw6q 3345 4 of of IN cord-006870-f5w6fw6q 3345 5 the the DT cord-006870-f5w6fw6q 3345 6 participants participant NNS cord-006870-f5w6fw6q 3345 7 at at IN cord-006870-f5w6fw6q 3345 8 this this DT cord-006870-f5w6fw6q 3345 9 workshop workshop NN cord-006870-f5w6fw6q 3345 10 had have VBD cord-006870-f5w6fw6q 3345 11 prior prior JJ cord-006870-f5w6fw6q 3345 12 ultrasound ultrasound NN cord-006870-f5w6fw6q 3345 13 experience experience NN cord-006870-f5w6fw6q 3345 14 , , , cord-006870-f5w6fw6q 3345 15 many many JJ cord-006870-f5w6fw6q 3345 16 are be VBP cord-006870-f5w6fw6q 3345 17 still still RB cord-006870-f5w6fw6q 3345 18 uncomfortable uncomfortable JJ cord-006870-f5w6fw6q 3345 19 with with IN cord-006870-f5w6fw6q 3345 20 their -PRON- PRP$ cord-006870-f5w6fw6q 3345 21 ultrasound ultrasound NN cord-006870-f5w6fw6q 3345 22 competency competency NN cord-006870-f5w6fw6q 3345 23 . . . cord-006870-f5w6fw6q 3346 1 The the DT cord-006870-f5w6fw6q 3346 2 format format NN cord-006870-f5w6fw6q 3346 3 of of IN cord-006870-f5w6fw6q 3346 4 didactics didactic NNS cord-006870-f5w6fw6q 3346 5 and and CC cord-006870-f5w6fw6q 3346 6 hands hand NNS cord-006870-f5w6fw6q 3346 7 - - HYPH cord-006870-f5w6fw6q 3346 8 on on RP cord-006870-f5w6fw6q 3346 9 small small JJ cord-006870-f5w6fw6q 3346 10 group group NN cord-006870-f5w6fw6q 3346 11 practice practice NN cord-006870-f5w6fw6q 3346 12 improved improve VBD cord-006870-f5w6fw6q 3346 13 the the DT cord-006870-f5w6fw6q 3346 14 comfort comfort NN cord-006870-f5w6fw6q 3346 15 level level NN cord-006870-f5w6fw6q 3346 16 as as RB cord-006870-f5w6fw6q 3346 17 well well RB cord-006870-f5w6fw6q 3346 18 as as IN cord-006870-f5w6fw6q 3346 19 overall overall JJ cord-006870-f5w6fw6q 3346 20 ultrasound ultrasound NN cord-006870-f5w6fw6q 3346 21 knowledge knowledge NN cord-006870-f5w6fw6q 3346 22 of of IN cord-006870-f5w6fw6q 3346 23 these these DT cord-006870-f5w6fw6q 3346 24 participants participant NNS cord-006870-f5w6fw6q 3346 25 . . . cord-006870-f5w6fw6q 3347 1 Additional additional JJ cord-006870-f5w6fw6q 3347 2 opportunities opportunity NNS cord-006870-f5w6fw6q 3347 3 for for IN cord-006870-f5w6fw6q 3347 4 point point NN cord-006870-f5w6fw6q 3347 5 - - HYPH cord-006870-f5w6fw6q 3347 6 of of IN cord-006870-f5w6fw6q 3347 7 - - HYPH cord-006870-f5w6fw6q 3347 8 care care NN cord-006870-f5w6fw6q 3347 9 ultrasound ultrasound NN cord-006870-f5w6fw6q 3347 10 training training NN cord-006870-f5w6fw6q 3347 11 should should MD cord-006870-f5w6fw6q 3347 12 be be VB cord-006870-f5w6fw6q 3347 13 considered consider VBN cord-006870-f5w6fw6q 3347 14 in in IN cord-006870-f5w6fw6q 3347 15 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3347 16 care care NN cord-006870-f5w6fw6q 3347 17 fellowships fellowship NNS cord-006870-f5w6fw6q 3347 18 and and CC cord-006870-f5w6fw6q 3347 19 meetings meeting NNS cord-006870-f5w6fw6q 3347 20 . . . cord-006870-f5w6fw6q 3348 1 Event event NN cord-006870-f5w6fw6q 3348 2 Related related JJ cord-006870-f5w6fw6q 3348 3 potentials potential NNS cord-006870-f5w6fw6q 3348 4 ( ( -LRB- cord-006870-f5w6fw6q 3348 5 ERPs ERPs NNP cord-006870-f5w6fw6q 3348 6 ) ) -RRB- cord-006870-f5w6fw6q 3348 7 allow allow VBP cord-006870-f5w6fw6q 3348 8 assessment assessment NN cord-006870-f5w6fw6q 3348 9 of of IN cord-006870-f5w6fw6q 3348 10 cognitive cognitive JJ cord-006870-f5w6fw6q 3348 11 processing processing NN cord-006870-f5w6fw6q 3348 12 in in IN cord-006870-f5w6fw6q 3348 13 unconscious unconscious JJ cord-006870-f5w6fw6q 3348 14 brain brain NN cord-006870-f5w6fw6q 3348 15 - - HYPH cord-006870-f5w6fw6q 3348 16 injured injure VBN cord-006870-f5w6fw6q 3348 17 patients patient NNS cord-006870-f5w6fw6q 3348 18 . . . cord-006870-f5w6fw6q 3349 1 Here here RB cord-006870-f5w6fw6q 3349 2 we -PRON- PRP cord-006870-f5w6fw6q 3349 3 explored explore VBD cord-006870-f5w6fw6q 3349 4 the the DT cord-006870-f5w6fw6q 3349 5 diagnostic diagnostic JJ cord-006870-f5w6fw6q 3349 6 and and CC cord-006870-f5w6fw6q 3349 7 prognostic prognostic JJ cord-006870-f5w6fw6q 3349 8 value value NN cord-006870-f5w6fw6q 3349 9 of of IN cord-006870-f5w6fw6q 3349 10 ERPs erp NNS cord-006870-f5w6fw6q 3349 11 obtained obtain VBN cord-006870-f5w6fw6q 3349 12 shortly shortly RB cord-006870-f5w6fw6q 3349 13 after after IN cord-006870-f5w6fw6q 3349 14 brain brain NN cord-006870-f5w6fw6q 3349 15 injury injury NN cord-006870-f5w6fw6q 3349 16 . . . cord-006870-f5w6fw6q 3350 1 We -PRON- PRP cord-006870-f5w6fw6q 3350 2 prospectively prospectively RB cord-006870-f5w6fw6q 3350 3 collected collect VBD cord-006870-f5w6fw6q 3350 4 a a DT cord-006870-f5w6fw6q 3350 5 comprehensive comprehensive JJ cord-006870-f5w6fw6q 3350 6 ERP ERP NNP cord-006870-f5w6fw6q 3350 7 paradigm paradigm NN cord-006870-f5w6fw6q 3350 8 labeled label VBN cord-006870-f5w6fw6q 3350 9 " " `` cord-006870-f5w6fw6q 3350 10 Local Local NNP cord-006870-f5w6fw6q 3350 11 Global global JJ cord-006870-f5w6fw6q 3350 12 paradigm paradigm NN cord-006870-f5w6fw6q 3350 13 " " '' cord-006870-f5w6fw6q 3350 14 from from IN cord-006870-f5w6fw6q 3350 15 a a DT cord-006870-f5w6fw6q 3350 16 consecutive consecutive JJ cord-006870-f5w6fw6q 3350 17 series series NN cord-006870-f5w6fw6q 3350 18 of of IN cord-006870-f5w6fw6q 3350 19 unconscious unconscious JJ cord-006870-f5w6fw6q 3350 20 patients patient NNS cord-006870-f5w6fw6q 3350 21 with with IN cord-006870-f5w6fw6q 3350 22 acute acute JJ cord-006870-f5w6fw6q 3350 23 brain brain NN cord-006870-f5w6fw6q 3350 24 injury injury NN cord-006870-f5w6fw6q 3350 25 . . . cord-006870-f5w6fw6q 3351 1 This this DT cord-006870-f5w6fw6q 3351 2 auditory auditory JJ cord-006870-f5w6fw6q 3351 3 paradigm paradigm NN cord-006870-f5w6fw6q 3351 4 allows allow VBZ cord-006870-f5w6fw6q 3351 5 the the DT cord-006870-f5w6fw6q 3351 6 assessment assessment NN cord-006870-f5w6fw6q 3351 7 of of IN cord-006870-f5w6fw6q 3351 8 : : : cord-006870-f5w6fw6q 3351 9 1 1 LS cord-006870-f5w6fw6q 3351 10 ) ) -RRB- cord-006870-f5w6fw6q 3351 11 cortical cortical JJ cord-006870-f5w6fw6q 3351 12 responses response NNS cord-006870-f5w6fw6q 3351 13 , , , cord-006870-f5w6fw6q 3351 14 2 2 CD cord-006870-f5w6fw6q 3351 15 ) ) -RRB- cord-006870-f5w6fw6q 3351 16 unconscious unconscious JJ cord-006870-f5w6fw6q 3351 17 cognitive cognitive JJ cord-006870-f5w6fw6q 3351 18 processing processing NN cord-006870-f5w6fw6q 3351 19 , , , cord-006870-f5w6fw6q 3351 20 3 3 CD cord-006870-f5w6fw6q 3351 21 ) ) -RRB- cord-006870-f5w6fw6q 3351 22 unconscious unconscious JJ cord-006870-f5w6fw6q 3351 23 focusing focusing NN cord-006870-f5w6fw6q 3351 24 of of IN cord-006870-f5w6fw6q 3351 25 attention attention NN cord-006870-f5w6fw6q 3351 26 , , , cord-006870-f5w6fw6q 3351 27 and and CC cord-006870-f5w6fw6q 3351 28 4 4 LS cord-006870-f5w6fw6q 3351 29 ) ) -RRB- cord-006870-f5w6fw6q 3351 30 conscious conscious JJ cord-006870-f5w6fw6q 3351 31 processing processing NN cord-006870-f5w6fw6q 3351 32 of of IN cord-006870-f5w6fw6q 3351 33 sounds sound NNS cord-006870-f5w6fw6q 3351 34 . . . cord-006870-f5w6fw6q 3352 1 Levels level NNS cord-006870-f5w6fw6q 3352 2 of of IN cord-006870-f5w6fw6q 3352 3 consciousness consciousness NN cord-006870-f5w6fw6q 3352 4 assessed assess VBN cord-006870-f5w6fw6q 3352 5 with with IN cord-006870-f5w6fw6q 3352 6 the the DT cord-006870-f5w6fw6q 3352 7 Coma Coma NNP cord-006870-f5w6fw6q 3352 8 Recovery Recovery NNP cord-006870-f5w6fw6q 3352 9 Scale scale NN cord-006870-f5w6fw6q 3352 10 - - HYPH cord-006870-f5w6fw6q 3352 11 Revised revise VBN cord-006870-f5w6fw6q 3352 12 ( ( -LRB- cord-006870-f5w6fw6q 3352 13 CRS CRS NNP cord-006870-f5w6fw6q 3352 14 - - HYPH cord-006870-f5w6fw6q 3352 15 R R NNP cord-006870-f5w6fw6q 3352 16 ) ) -RRB- cord-006870-f5w6fw6q 3352 17 at at IN cord-006870-f5w6fw6q 3352 18 the the DT cord-006870-f5w6fw6q 3352 19 time time NN cord-006870-f5w6fw6q 3352 20 of of IN cord-006870-f5w6fw6q 3352 21 recording recording NN cord-006870-f5w6fw6q 3352 22 were be VBD cord-006870-f5w6fw6q 3352 23 correlated correlate VBN cord-006870-f5w6fw6q 3352 24 with with IN cord-006870-f5w6fw6q 3352 25 the the DT cord-006870-f5w6fw6q 3352 26 presence presence NN cord-006870-f5w6fw6q 3352 27 / / SYM cord-006870-f5w6fw6q 3352 28 absence absence NN cord-006870-f5w6fw6q 3352 29 of of IN cord-006870-f5w6fw6q 3352 30 each each DT cord-006870-f5w6fw6q 3352 31 ERPs ERPs NNP cord-006870-f5w6fw6q 3352 32 component component NN cord-006870-f5w6fw6q 3352 33 and and CC cord-006870-f5w6fw6q 3352 34 functional functional JJ cord-006870-f5w6fw6q 3352 35 connectivity connectivity NN cord-006870-f5w6fw6q 3352 36 / / SYM cord-006870-f5w6fw6q 3352 37 complexity complexity NN cord-006870-f5w6fw6q 3352 38 measures measure NNS cord-006870-f5w6fw6q 3352 39 . . . cord-006870-f5w6fw6q 3353 1 We -PRON- PRP cord-006870-f5w6fw6q 3353 2 tested test VBD cord-006870-f5w6fw6q 3353 3 the the DT cord-006870-f5w6fw6q 3353 4 prognostic prognostic JJ cord-006870-f5w6fw6q 3353 5 value value NN cord-006870-f5w6fw6q 3353 6 of of IN cord-006870-f5w6fw6q 3353 7 each each DT cord-006870-f5w6fw6q 3353 8 measure measure NN cord-006870-f5w6fw6q 3353 9 for for IN cord-006870-f5w6fw6q 3353 10 recovery recovery NN cord-006870-f5w6fw6q 3353 11 of of IN cord-006870-f5w6fw6q 3353 12 consciousness consciousness NN cord-006870-f5w6fw6q 3353 13 prior prior RB cord-006870-f5w6fw6q 3353 14 to to IN cord-006870-f5w6fw6q 3353 15 discharge discharge NN cord-006870-f5w6fw6q 3353 16 . . . cord-006870-f5w6fw6q 3354 1 We -PRON- PRP cord-006870-f5w6fw6q 3354 2 analyzed analyze VBD cord-006870-f5w6fw6q 3354 3 32 32 CD cord-006870-f5w6fw6q 3354 4 recordings recording NNS cord-006870-f5w6fw6q 3354 5 from from IN cord-006870-f5w6fw6q 3354 6 15 15 CD cord-006870-f5w6fw6q 3354 7 patients patient NNS cord-006870-f5w6fw6q 3354 8 ( ( -LRB- cord-006870-f5w6fw6q 3354 9 median median JJ cord-006870-f5w6fw6q 3354 10 recordings recording NNS cord-006870-f5w6fw6q 3354 11 per per IN cord-006870-f5w6fw6q 3354 12 patients patient NNS cord-006870-f5w6fw6q 3354 13 2[IQR 2[iqr CD cord-006870-f5w6fw6q 3354 14 1,3 1,3 CD cord-006870-f5w6fw6q 3354 15 ] ] -RRB- cord-006870-f5w6fw6q 3354 16 ) ) -RRB- cord-006870-f5w6fw6q 3354 17 . . . cord-006870-f5w6fw6q 3355 1 Recordings recording NNS cord-006870-f5w6fw6q 3355 2 were be VBD cord-006870-f5w6fw6q 3355 3 made make VBN cord-006870-f5w6fw6q 3355 4 6 6 CD cord-006870-f5w6fw6q 3355 5 [ [ -LRB- cord-006870-f5w6fw6q 3355 6 IQR IQR NNP cord-006870-f5w6fw6q 3355 7 4.25,10.75 4.25,10.75 CD cord-006870-f5w6fw6q 3355 8 ] ] -RRB- cord-006870-f5w6fw6q 3355 9 days day NNS cord-006870-f5w6fw6q 3355 10 after after IN cord-006870-f5w6fw6q 3355 11 brain brain NN cord-006870-f5w6fw6q 3355 12 injury injury NN cord-006870-f5w6fw6q 3355 13 and and CC cord-006870-f5w6fw6q 3355 14 all all DT cord-006870-f5w6fw6q 3355 15 patients patient NNS cord-006870-f5w6fw6q 3355 16 were be VBD cord-006870-f5w6fw6q 3355 17 unconscious unconscious JJ cord-006870-f5w6fw6q 3355 18 at at IN cord-006870-f5w6fw6q 3355 19 the the DT cord-006870-f5w6fw6q 3355 20 time time NN cord-006870-f5w6fw6q 3355 21 of of IN cord-006870-f5w6fw6q 3355 22 the the DT cord-006870-f5w6fw6q 3355 23 initial initial JJ cord-006870-f5w6fw6q 3355 24 recording recording NN cord-006870-f5w6fw6q 3355 25 . . . cord-006870-f5w6fw6q 3356 1 Underlying underlying JJ cord-006870-f5w6fw6q 3356 2 etiologies etiology NNS cord-006870-f5w6fw6q 3356 3 included include VBN cord-006870-f5w6fw6q 3356 4 ICH(N=6 ICH(N=6 NNP cord-006870-f5w6fw6q 3356 5 ) ) -RRB- cord-006870-f5w6fw6q 3356 6 , , , cord-006870-f5w6fw6q 3356 7 SAH(N=4 SAH(N=4 NNP cord-006870-f5w6fw6q 3356 8 ) ) -RRB- cord-006870-f5w6fw6q 3356 9 , , , cord-006870-f5w6fw6q 3356 10 TBI(2 TBI(2 NNP cord-006870-f5w6fw6q 3356 11 ) ) -RRB- cord-006870-f5w6fw6q 3356 12 and and CC cord-006870-f5w6fw6q 3356 13 other other JJ cord-006870-f5w6fw6q 3356 14 ( ( -LRB- cord-006870-f5w6fw6q 3356 15 N=3 N=3 NNP cord-006870-f5w6fw6q 3356 16 ) ) -RRB- cord-006870-f5w6fw6q 3356 17 . . . cord-006870-f5w6fw6q 3357 1 There there EX cord-006870-f5w6fw6q 3357 2 were be VBD cord-006870-f5w6fw6q 3357 3 trends trend NNS cord-006870-f5w6fw6q 3357 4 for for IN cord-006870-f5w6fw6q 3357 5 higher high JJR cord-006870-f5w6fw6q 3357 6 CRS CRS NNP cord-006870-f5w6fw6q 3357 7 - - HYPH cord-006870-f5w6fw6q 3357 8 R R NNP cord-006870-f5w6fw6q 3357 9 scores score NNS cord-006870-f5w6fw6q 3357 10 in in IN cord-006870-f5w6fw6q 3357 11 patients patient NNS cord-006870-f5w6fw6q 3357 12 with with IN cord-006870-f5w6fw6q 3357 13 preserved preserve VBN cord-006870-f5w6fw6q 3357 14 ERP ERP NNP cord-006870-f5w6fw6q 3357 15 components component NNS cord-006870-f5w6fw6q 3357 16 . . . cord-006870-f5w6fw6q 3358 1 CRS CRS NNP cord-006870-f5w6fw6q 3358 2 - - HYPH cord-006870-f5w6fw6q 3358 3 R R NNP cord-006870-f5w6fw6q 3358 4 scores score NNS cord-006870-f5w6fw6q 3358 5 correlated correlate VBN cord-006870-f5w6fw6q 3358 6 with with IN cord-006870-f5w6fw6q 3358 7 the the DT cord-006870-f5w6fw6q 3358 8 functional functional JJ cord-006870-f5w6fw6q 3358 9 connectivity connectivity NN cord-006870-f5w6fw6q 3358 10 indexed index VBN cord-006870-f5w6fw6q 3358 11 ( ( -LRB- cord-006870-f5w6fw6q 3358 12 rho=0.44 rho=0.44 VBZ cord-006870-f5w6fw6q 3358 13 ; ; : cord-006870-f5w6fw6q 3358 14 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 3358 15 ) ) -RRB- cord-006870-f5w6fw6q 3358 16 but but CC cord-006870-f5w6fw6q 3358 17 not not RB cord-006870-f5w6fw6q 3358 18 with with IN cord-006870-f5w6fw6q 3358 19 complexity complexity NN cord-006870-f5w6fw6q 3358 20 measures measure NNS cord-006870-f5w6fw6q 3358 21 . . . cord-006870-f5w6fw6q 3359 1 Five five CD cord-006870-f5w6fw6q 3359 2 ( ( -LRB- cord-006870-f5w6fw6q 3359 3 33 33 CD cord-006870-f5w6fw6q 3359 4 % % NN cord-006870-f5w6fw6q 3359 5 ) ) -RRB- cord-006870-f5w6fw6q 3359 6 patients patient NNS cord-006870-f5w6fw6q 3359 7 regained regain VBD cord-006870-f5w6fw6q 3359 8 consciousness consciousness NN cord-006870-f5w6fw6q 3359 9 ( ( -LRB- cord-006870-f5w6fw6q 3359 10 within within IN cord-006870-f5w6fw6q 3359 11 6 6 CD cord-006870-f5w6fw6q 3359 12 to to TO cord-006870-f5w6fw6q 3359 13 42 42 CD cord-006870-f5w6fw6q 3359 14 days day NNS cord-006870-f5w6fw6q 3359 15 from from IN cord-006870-f5w6fw6q 3359 16 brain brain NN cord-006870-f5w6fw6q 3359 17 injury injury NN cord-006870-f5w6fw6q 3359 18 ) ) -RRB- cord-006870-f5w6fw6q 3359 19 . . . cord-006870-f5w6fw6q 3360 1 One one CD cord-006870-f5w6fw6q 3360 2 of of IN cord-006870-f5w6fw6q 3360 3 these these DT cord-006870-f5w6fw6q 3360 4 patients patient NNS cord-006870-f5w6fw6q 3360 5 had have VBD cord-006870-f5w6fw6q 3360 6 to to TO cord-006870-f5w6fw6q 3360 7 be be VB cord-006870-f5w6fw6q 3360 8 excluded exclude VBN cord-006870-f5w6fw6q 3360 9 due due IN cord-006870-f5w6fw6q 3360 10 to to IN cord-006870-f5w6fw6q 3360 11 poor poor JJ cord-006870-f5w6fw6q 3360 12 quality quality NN cord-006870-f5w6fw6q 3360 13 recording recording NN cord-006870-f5w6fw6q 3360 14 . . . cord-006870-f5w6fw6q 3361 1 All all PDT cord-006870-f5w6fw6q 3361 2 the the DT cord-006870-f5w6fw6q 3361 3 4(100 4(100 CD cord-006870-f5w6fw6q 3361 4 % % NN cord-006870-f5w6fw6q 3361 5 ) ) -RRB- cord-006870-f5w6fw6q 3361 6 remaining remain VBG cord-006870-f5w6fw6q 3361 7 patients patient NNS cord-006870-f5w6fw6q 3361 8 had have VBD cord-006870-f5w6fw6q 3361 9 the the DT cord-006870-f5w6fw6q 3361 10 three three CD cord-006870-f5w6fw6q 3361 11 type type NN cord-006870-f5w6fw6q 3361 12 of of IN cord-006870-f5w6fw6q 3361 13 non non JJ cord-006870-f5w6fw6q 3361 14 - - JJ cord-006870-f5w6fw6q 3361 15 conscious conscious JJ cord-006870-f5w6fw6q 3361 16 responses response NNS cord-006870-f5w6fw6q 3361 17 preserved preserve VBN cord-006870-f5w6fw6q 3361 18 on on IN cord-006870-f5w6fw6q 3361 19 at at RB cord-006870-f5w6fw6q 3361 20 least least RBS cord-006870-f5w6fw6q 3361 21 one one CD cord-006870-f5w6fw6q 3361 22 recording recording NN cord-006870-f5w6fw6q 3361 23 in in IN cord-006870-f5w6fw6q 3361 24 comparison comparison NN cord-006870-f5w6fw6q 3361 25 to to IN cord-006870-f5w6fw6q 3361 26 only only RB cord-006870-f5w6fw6q 3361 27 3(30 3(30 CD cord-006870-f5w6fw6q 3361 28 % % NN cord-006870-f5w6fw6q 3361 29 ) ) -RRB- cord-006870-f5w6fw6q 3361 30 among among IN cord-006870-f5w6fw6q 3361 31 patient patient NN cord-006870-f5w6fw6q 3361 32 who who WP cord-006870-f5w6fw6q 3361 33 did do VBD cord-006870-f5w6fw6q 3361 34 not not RB cord-006870-f5w6fw6q 3361 35 recover recover VB cord-006870-f5w6fw6q 3361 36 consciousness consciousness NN cord-006870-f5w6fw6q 3362 1 ( ( -LRB- cord-006870-f5w6fw6q 3362 2 Fischer Fischer NNP cord-006870-f5w6fw6q 3362 3 p p NN cord-006870-f5w6fw6q 3362 4 - - HYPH cord-006870-f5w6fw6q 3362 5 value value NN cord-006870-f5w6fw6q 3362 6 = = SYM cord-006870-f5w6fw6q 3362 7 0.07 0.07 CD cord-006870-f5w6fw6q 3362 8 ) ) -RRB- cord-006870-f5w6fw6q 3362 9 . . . cord-006870-f5w6fw6q 3363 1 Similarly similarly RB cord-006870-f5w6fw6q 3363 2 , , , cord-006870-f5w6fw6q 3363 3 connectivity connectivity NN cord-006870-f5w6fw6q 3363 4 was be VBD cord-006870-f5w6fw6q 3363 5 greater great JJR cord-006870-f5w6fw6q 3363 6 in in IN cord-006870-f5w6fw6q 3363 7 patients patient NNS cord-006870-f5w6fw6q 3363 8 who who WP cord-006870-f5w6fw6q 3363 9 regained regain VBD cord-006870-f5w6fw6q 3363 10 consciousness consciousness NN cord-006870-f5w6fw6q 3363 11 ( ( -LRB- cord-006870-f5w6fw6q 3363 12 0.0855 0.0855 CD cord-006870-f5w6fw6q 3363 13 vs vs IN cord-006870-f5w6fw6q 3363 14 0.0797 0.0797 CD cord-006870-f5w6fw6q 3363 15 ; ; : cord-006870-f5w6fw6q 3363 16 p=0.05 p=0.05 JJ cord-006870-f5w6fw6q 3363 17 ) ) -RRB- cord-006870-f5w6fw6q 3363 18 but but CC cord-006870-f5w6fw6q 3363 19 the the DT cord-006870-f5w6fw6q 3363 20 complexity complexity NN cord-006870-f5w6fw6q 3363 21 was be VBD cord-006870-f5w6fw6q 3363 22 similar similar JJ cord-006870-f5w6fw6q 3363 23 . . . cord-006870-f5w6fw6q 3364 1 Simple simple JJ cord-006870-f5w6fw6q 3364 2 bedside bedside NN cord-006870-f5w6fw6q 3364 3 ERP ERP NNP cord-006870-f5w6fw6q 3364 4 responses response NNS cord-006870-f5w6fw6q 3364 5 indexing indexing NN cord-006870-f5w6fw6q 3364 6 cognitive cognitive JJ cord-006870-f5w6fw6q 3364 7 processing processing NN cord-006870-f5w6fw6q 3364 8 during during IN cord-006870-f5w6fw6q 3364 9 the the DT cord-006870-f5w6fw6q 3364 10 Local Local NNP cord-006870-f5w6fw6q 3364 11 Global Global NNP cord-006870-f5w6fw6q 3364 12 paradigm paradigm NN cord-006870-f5w6fw6q 3364 13 obtained obtain VBN cord-006870-f5w6fw6q 3364 14 shortly shortly RB cord-006870-f5w6fw6q 3364 15 after after IN cord-006870-f5w6fw6q 3364 16 brain brain NN cord-006870-f5w6fw6q 3364 17 injury injury NN cord-006870-f5w6fw6q 3364 18 correlate correlate VBP cord-006870-f5w6fw6q 3364 19 with with IN cord-006870-f5w6fw6q 3364 20 the the DT cord-006870-f5w6fw6q 3364 21 level level NN cord-006870-f5w6fw6q 3364 22 of of IN cord-006870-f5w6fw6q 3364 23 consciousness consciousness NN cord-006870-f5w6fw6q 3365 1 but but CC cord-006870-f5w6fw6q 3365 2 , , , cord-006870-f5w6fw6q 3365 3 more more RBR cord-006870-f5w6fw6q 3365 4 importantly importantly RB cord-006870-f5w6fw6q 3365 5 , , , cord-006870-f5w6fw6q 3365 6 the the DT cord-006870-f5w6fw6q 3365 7 probability probability NN cord-006870-f5w6fw6q 3365 8 to to TO cord-006870-f5w6fw6q 3365 9 recover recover VB cord-006870-f5w6fw6q 3365 10 consciousness consciousness NN cord-006870-f5w6fw6q 3365 11 . . . cord-006870-f5w6fw6q 3366 1 Over over IN cord-006870-f5w6fw6q 3366 2 a a DT cord-006870-f5w6fw6q 3366 3 decade decade NN cord-006870-f5w6fw6q 3366 4 ago ago RB cord-006870-f5w6fw6q 3366 5 , , , cord-006870-f5w6fw6q 3366 6 the the DT cord-006870-f5w6fw6q 3366 7 Institute Institute NNP cord-006870-f5w6fw6q 3366 8 of of IN cord-006870-f5w6fw6q 3366 9 Medicine Medicine NNP cord-006870-f5w6fw6q 3366 10 introduced introduce VBD cord-006870-f5w6fw6q 3366 11 Family Family NNP cord-006870-f5w6fw6q 3366 12 - - HYPH cord-006870-f5w6fw6q 3366 13 Centered Centered NNP cord-006870-f5w6fw6q 3366 14 Care Care NNP cord-006870-f5w6fw6q 3366 15 ( ( -LRB- cord-006870-f5w6fw6q 3366 16 FCC FCC NNP cord-006870-f5w6fw6q 3366 17 ) ) -RRB- cord-006870-f5w6fw6q 3366 18 as as IN cord-006870-f5w6fw6q 3366 19 a a DT cord-006870-f5w6fw6q 3366 20 vital vital JJ cord-006870-f5w6fw6q 3366 21 aspect aspect NN cord-006870-f5w6fw6q 3366 22 of of IN cord-006870-f5w6fw6q 3366 23 quality quality NN cord-006870-f5w6fw6q 3366 24 health health NN cord-006870-f5w6fw6q 3366 25 care care NN cord-006870-f5w6fw6q 3366 26 by by IN cord-006870-f5w6fw6q 3366 27 strongly strongly RB cord-006870-f5w6fw6q 3366 28 recommending recommend VBG cord-006870-f5w6fw6q 3366 29 that that IN cord-006870-f5w6fw6q 3366 30 family family NN cord-006870-f5w6fw6q 3366 31 members member NNS cord-006870-f5w6fw6q 3366 32 of of IN cord-006870-f5w6fw6q 3366 33 intensive intensive JJ cord-006870-f5w6fw6q 3366 34 care care NN cord-006870-f5w6fw6q 3366 35 unit unit NN cord-006870-f5w6fw6q 3366 36 ( ( -LRB- cord-006870-f5w6fw6q 3366 37 ICU ICU NNP cord-006870-f5w6fw6q 3366 38 ) ) -RRB- cord-006870-f5w6fw6q 3366 39 patients patient NNS cord-006870-f5w6fw6q 3366 40 be be VB cord-006870-f5w6fw6q 3366 41 actively actively RB cord-006870-f5w6fw6q 3366 42 involved involve VBN cord-006870-f5w6fw6q 3366 43 in in IN cord-006870-f5w6fw6q 3366 44 decision decision NN cord-006870-f5w6fw6q 3366 45 - - HYPH cord-006870-f5w6fw6q 3366 46 making making NN cord-006870-f5w6fw6q 3366 47 . . . cord-006870-f5w6fw6q 3367 1 While while IN cord-006870-f5w6fw6q 3367 2 there there EX cord-006870-f5w6fw6q 3367 3 are be VBP cord-006870-f5w6fw6q 3367 4 many many JJ cord-006870-f5w6fw6q 3367 5 resources resource NNS cord-006870-f5w6fw6q 3367 6 to to TO cord-006870-f5w6fw6q 3367 7 help help VB cord-006870-f5w6fw6q 3367 8 ICU ICU NNP cord-006870-f5w6fw6q 3367 9 staff staff NN cord-006870-f5w6fw6q 3367 10 conduct conduct NN cord-006870-f5w6fw6q 3367 11 meetings meeting NNS cord-006870-f5w6fw6q 3367 12 and and CC cord-006870-f5w6fw6q 3367 13 provide provide VB cord-006870-f5w6fw6q 3367 14 information information NN cord-006870-f5w6fw6q 3367 15 to to IN cord-006870-f5w6fw6q 3367 16 families family NNS cord-006870-f5w6fw6q 3367 17 , , , cord-006870-f5w6fw6q 3367 18 the the DT cord-006870-f5w6fw6q 3367 19 latest late JJS cord-006870-f5w6fw6q 3367 20 Society Society NNP cord-006870-f5w6fw6q 3367 21 of of IN cord-006870-f5w6fw6q 3367 22 Critical Critical NNP cord-006870-f5w6fw6q 3367 23 Care Care NNP cord-006870-f5w6fw6q 3367 24 Medicine Medicine NNP cord-006870-f5w6fw6q 3367 25 guidelines guideline NNS cord-006870-f5w6fw6q 3367 26 for for IN cord-006870-f5w6fw6q 3367 27 FCC FCC NNP cord-006870-f5w6fw6q 3367 28 recommend recommend VBP cord-006870-f5w6fw6q 3367 29 the the DT cord-006870-f5w6fw6q 3367 30 implementation implementation NN cord-006870-f5w6fw6q 3367 31 of of IN cord-006870-f5w6fw6q 3367 32 communication communication NN cord-006870-f5w6fw6q 3367 33 and and CC cord-006870-f5w6fw6q 3367 34 decision decision NN cord-006870-f5w6fw6q 3367 35 support support NN cord-006870-f5w6fw6q 3367 36 tools tool NNS cord-006870-f5w6fw6q 3367 37 for for IN cord-006870-f5w6fw6q 3367 38 family family NN cord-006870-f5w6fw6q 3367 39 members member NNS cord-006870-f5w6fw6q 3367 40 to to TO cord-006870-f5w6fw6q 3367 41 use use VB cord-006870-f5w6fw6q 3367 42 . . . cord-006870-f5w6fw6q 3368 1 Electronic electronic JJ cord-006870-f5w6fw6q 3368 2 decision decision NN cord-006870-f5w6fw6q 3368 3 support support NN cord-006870-f5w6fw6q 3368 4 tools tool NNS cord-006870-f5w6fw6q 3368 5 such such JJ cord-006870-f5w6fw6q 3368 6 as as IN cord-006870-f5w6fw6q 3368 7 My -PRON- PRP$ cord-006870-f5w6fw6q 3368 8 ICU ICU NNP cord-006870-f5w6fw6q 3368 9 Guide Guide NNP cord-006870-f5w6fw6q 3368 10 have have VBP cord-006870-f5w6fw6q 3368 11 been be VBN cord-006870-f5w6fw6q 3368 12 effective effective JJ cord-006870-f5w6fw6q 3368 13 in in IN cord-006870-f5w6fw6q 3368 14 pilot pilot NN cord-006870-f5w6fw6q 3368 15 studies study NNS cord-006870-f5w6fw6q 3368 16 at at IN cord-006870-f5w6fw6q 3368 17 allowing allow VBG cord-006870-f5w6fw6q 3368 18 family family NN cord-006870-f5w6fw6q 3368 19 members member NNS cord-006870-f5w6fw6q 3368 20 to to TO cord-006870-f5w6fw6q 3368 21 customize customize VB cord-006870-f5w6fw6q 3368 22 information information NN cord-006870-f5w6fw6q 3368 23 delivery delivery NN cord-006870-f5w6fw6q 3368 24 and and CC cord-006870-f5w6fw6q 3368 25 communicate communicate VB cord-006870-f5w6fw6q 3368 26 their -PRON- PRP$ cord-006870-f5w6fw6q 3368 27 preferences preference NNS cord-006870-f5w6fw6q 3368 28 to to IN cord-006870-f5w6fw6q 3368 29 ICU ICU NNP cord-006870-f5w6fw6q 3368 30 staff staff NN cord-006870-f5w6fw6q 3368 31 . . . cord-006870-f5w6fw6q 3369 1 We -PRON- PRP cord-006870-f5w6fw6q 3369 2 sought seek VBD cord-006870-f5w6fw6q 3369 3 to to TO cord-006870-f5w6fw6q 3369 4 integrate integrate VB cord-006870-f5w6fw6q 3369 5 a a DT cord-006870-f5w6fw6q 3369 6 decision decision NN cord-006870-f5w6fw6q 3369 7 support support NN cord-006870-f5w6fw6q 3369 8 and and CC cord-006870-f5w6fw6q 3369 9 communication communication NN cord-006870-f5w6fw6q 3369 10 tool tool NN cord-006870-f5w6fw6q 3369 11 for for IN cord-006870-f5w6fw6q 3369 12 families family NNS cord-006870-f5w6fw6q 3369 13 into into IN cord-006870-f5w6fw6q 3369 14 an an DT cord-006870-f5w6fw6q 3369 15 electronic electronic JJ cord-006870-f5w6fw6q 3369 16 patient patient NN cord-006870-f5w6fw6q 3369 17 portal portal NN cord-006870-f5w6fw6q 3369 18 . . . cord-006870-f5w6fw6q 3370 1 We -PRON- PRP cord-006870-f5w6fw6q 3370 2 developed develop VBD cord-006870-f5w6fw6q 3370 3 an an DT cord-006870-f5w6fw6q 3370 4 electronic electronic JJ cord-006870-f5w6fw6q 3370 5 patient patient NN cord-006870-f5w6fw6q 3370 6 and and CC cord-006870-f5w6fw6q 3370 7 family family NN cord-006870-f5w6fw6q 3370 8 engagement engagement NN cord-006870-f5w6fw6q 3370 9 checklist checklist NN cord-006870-f5w6fw6q 3370 10 for for IN cord-006870-f5w6fw6q 3370 11 the the DT cord-006870-f5w6fw6q 3370 12 neurointensive neurointensive NNP cord-006870-f5w6fw6q 3370 13 care care NN cord-006870-f5w6fw6q 3370 14 unit unit NN cord-006870-f5w6fw6q 3370 15 ( ( -LRB- cord-006870-f5w6fw6q 3370 16 NICU NICU NNP cord-006870-f5w6fw6q 3370 17 ) ) -RRB- cord-006870-f5w6fw6q 3370 18 using use VBG cord-006870-f5w6fw6q 3370 19 Doctella Doctella NNP cord-006870-f5w6fw6q 3370 20 ( ( -LRB- cord-006870-f5w6fw6q 3370 21 Patient Patient NNP cord-006870-f5w6fw6q 3370 22 Doctor Doctor NNP cord-006870-f5w6fw6q 3370 23 Technologies Technologies NNP cord-006870-f5w6fw6q 3370 24 , , , cord-006870-f5w6fw6q 3370 25 Sunnyvale Sunnyvale NNP cord-006870-f5w6fw6q 3370 26 , , , cord-006870-f5w6fw6q 3370 27 CA CA NNP cord-006870-f5w6fw6q 3370 28 ) ) -RRB- cord-006870-f5w6fw6q 3370 29 , , , cord-006870-f5w6fw6q 3370 30 an an DT cord-006870-f5w6fw6q 3370 31 existing exist VBG cord-006870-f5w6fw6q 3370 32 patient patient NN cord-006870-f5w6fw6q 3370 33 engagement engagement NN cord-006870-f5w6fw6q 3370 34 application application NN cord-006870-f5w6fw6q 3370 35 . . . cord-006870-f5w6fw6q 3371 1 Checklist checklist NN cord-006870-f5w6fw6q 3371 2 components component NNS cord-006870-f5w6fw6q 3371 3 included include VBD cord-006870-f5w6fw6q 3371 4 : : : cord-006870-f5w6fw6q 3371 5 identifying identify VBG cord-006870-f5w6fw6q 3371 6 a a DT cord-006870-f5w6fw6q 3371 7 spokesperson spokesperson NN cord-006870-f5w6fw6q 3371 8 , , , cord-006870-f5w6fw6q 3371 9 developing develop VBG cord-006870-f5w6fw6q 3371 10 an an DT cord-006870-f5w6fw6q 3371 11 advance advance NN cord-006870-f5w6fw6q 3371 12 directive directive NN cord-006870-f5w6fw6q 3371 13 , , , cord-006870-f5w6fw6q 3371 14 understanding understand VBG cord-006870-f5w6fw6q 3371 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 3371 16 and and CC cord-006870-f5w6fw6q 3371 17 prognosis prognosis NN cord-006870-f5w6fw6q 3371 18 , , , cord-006870-f5w6fw6q 3371 19 access access NN cord-006870-f5w6fw6q 3371 20 to to IN cord-006870-f5w6fw6q 3371 21 helpful helpful JJ cord-006870-f5w6fw6q 3371 22 resources resource NNS cord-006870-f5w6fw6q 3371 23 , , , cord-006870-f5w6fw6q 3371 24 and and CC cord-006870-f5w6fw6q 3371 25 a a DT cord-006870-f5w6fw6q 3371 26 family family NN cord-006870-f5w6fw6q 3371 27 meeting meeting NN cord-006870-f5w6fw6q 3371 28 guide guide NN cord-006870-f5w6fw6q 3371 29 and and CC cord-006870-f5w6fw6q 3371 30 planner planner NN cord-006870-f5w6fw6q 3371 31 . . . cord-006870-f5w6fw6q 3372 1 We -PRON- PRP cord-006870-f5w6fw6q 3372 2 presented present VBD cord-006870-f5w6fw6q 3372 3 the the DT cord-006870-f5w6fw6q 3372 4 checklist checklist NN cord-006870-f5w6fw6q 3372 5 to to IN cord-006870-f5w6fw6q 3372 6 our -PRON- PRP$ cord-006870-f5w6fw6q 3372 7 hospital hospital NN cord-006870-f5w6fw6q 3372 8 's 's POS cord-006870-f5w6fw6q 3372 9 Patient Patient NNP cord-006870-f5w6fw6q 3372 10 and and CC cord-006870-f5w6fw6q 3372 11 Family Family NNP cord-006870-f5w6fw6q 3372 12 Engagement Engagement NNP cord-006870-f5w6fw6q 3372 13 steering steering NN cord-006870-f5w6fw6q 3372 14 committee committee NN cord-006870-f5w6fw6q 3372 15 for for IN cord-006870-f5w6fw6q 3372 16 the the DT cord-006870-f5w6fw6q 3372 17 ICUs ICUs NNP cord-006870-f5w6fw6q 3372 18 and and CC cord-006870-f5w6fw6q 3372 19 received receive VBD cord-006870-f5w6fw6q 3372 20 useful useful JJ cord-006870-f5w6fw6q 3372 21 feedback feedback NN cord-006870-f5w6fw6q 3372 22 . . . cord-006870-f5w6fw6q 3373 1 The the DT cord-006870-f5w6fw6q 3373 2 checklist checklist NN cord-006870-f5w6fw6q 3373 3 will will MD cord-006870-f5w6fw6q 3373 4 also also RB cord-006870-f5w6fw6q 3373 5 be be VB cord-006870-f5w6fw6q 3373 6 vetted vet VBN cord-006870-f5w6fw6q 3373 7 by by IN cord-006870-f5w6fw6q 3373 8 the the DT cord-006870-f5w6fw6q 3373 9 hospital hospital NN cord-006870-f5w6fw6q 3373 10 's 's POS cord-006870-f5w6fw6q 3373 11 Patient Patient NNP cord-006870-f5w6fw6q 3373 12 and and CC cord-006870-f5w6fw6q 3373 13 Family Family NNP cord-006870-f5w6fw6q 3373 14 Advisory Advisory NNP cord-006870-f5w6fw6q 3373 15 Council Council NNP cord-006870-f5w6fw6q 3373 16 . . . cord-006870-f5w6fw6q 3374 1 Usability usability NN cord-006870-f5w6fw6q 3374 2 testing testing NN cord-006870-f5w6fw6q 3374 3 will will MD cord-006870-f5w6fw6q 3374 4 also also RB cord-006870-f5w6fw6q 3374 5 be be VB cord-006870-f5w6fw6q 3374 6 conducted conduct VBN cord-006870-f5w6fw6q 3374 7 . . . cord-006870-f5w6fw6q 3375 1 A a DT cord-006870-f5w6fw6q 3375 2 family family NN cord-006870-f5w6fw6q 3375 3 engagement engagement NN cord-006870-f5w6fw6q 3375 4 checklist checklist NN cord-006870-f5w6fw6q 3375 5 using use VBG cord-006870-f5w6fw6q 3375 6 an an DT cord-006870-f5w6fw6q 3375 7 electronic electronic JJ cord-006870-f5w6fw6q 3375 8 patient patient NN cord-006870-f5w6fw6q 3375 9 portal portal NN cord-006870-f5w6fw6q 3375 10 is be VBZ cord-006870-f5w6fw6q 3375 11 a a DT cord-006870-f5w6fw6q 3375 12 novel novel JJ cord-006870-f5w6fw6q 3375 13 strategy strategy NN cord-006870-f5w6fw6q 3375 14 to to TO cord-006870-f5w6fw6q 3375 15 enhance enhance VB cord-006870-f5w6fw6q 3375 16 communication communication NN cord-006870-f5w6fw6q 3375 17 in in IN cord-006870-f5w6fw6q 3375 18 the the DT cord-006870-f5w6fw6q 3375 19 NICU NICU NNP cord-006870-f5w6fw6q 3375 20 . . . cord-006870-f5w6fw6q 3376 1 Further further JJ cord-006870-f5w6fw6q 3376 2 validation validation NN cord-006870-f5w6fw6q 3376 3 of of IN cord-006870-f5w6fw6q 3376 4 the the DT cord-006870-f5w6fw6q 3376 5 tool tool NN cord-006870-f5w6fw6q 3376 6 is be VBZ cord-006870-f5w6fw6q 3376 7 needed need VBN cord-006870-f5w6fw6q 3376 8 . . . cord-006870-f5w6fw6q 3377 1 Applying apply VBG cord-006870-f5w6fw6q 3377 2 painful painful JJ cord-006870-f5w6fw6q 3377 3 stimuli stimulus NNS cord-006870-f5w6fw6q 3377 4 to to IN cord-006870-f5w6fw6q 3377 5 brain brain NN cord-006870-f5w6fw6q 3377 6 injured injure VBN cord-006870-f5w6fw6q 3377 7 patients patient NNS cord-006870-f5w6fw6q 3377 8 is be VBZ cord-006870-f5w6fw6q 3377 9 a a DT cord-006870-f5w6fw6q 3377 10 time time NN cord-006870-f5w6fw6q 3377 11 - - HYPH cord-006870-f5w6fw6q 3377 12 honored honor VBN cord-006870-f5w6fw6q 3377 13 practice practice NN cord-006870-f5w6fw6q 3377 14 assumed assume VBN cord-006870-f5w6fw6q 3377 15 to to TO cord-006870-f5w6fw6q 3377 16 provide provide VB cord-006870-f5w6fw6q 3377 17 valuable valuable JJ cord-006870-f5w6fw6q 3377 18 clinical clinical JJ cord-006870-f5w6fw6q 3377 19 information information NN cord-006870-f5w6fw6q 3377 20 for for IN cord-006870-f5w6fw6q 3377 21 diagnosis diagnosis NN cord-006870-f5w6fw6q 3377 22 , , , cord-006870-f5w6fw6q 3377 23 prognosis prognosis NN cord-006870-f5w6fw6q 3377 24 , , , cord-006870-f5w6fw6q 3377 25 and and CC cord-006870-f5w6fw6q 3377 26 potential potential JJ cord-006870-f5w6fw6q 3377 27 guidance guidance NN cord-006870-f5w6fw6q 3377 28 for for IN cord-006870-f5w6fw6q 3377 29 therapeutic therapeutic JJ cord-006870-f5w6fw6q 3377 30 interventions intervention NNS cord-006870-f5w6fw6q 3377 31 . . . cord-006870-f5w6fw6q 3378 1 However however RB cord-006870-f5w6fw6q 3378 2 , , , cord-006870-f5w6fw6q 3378 3 there there EX cord-006870-f5w6fw6q 3378 4 is be VBZ cord-006870-f5w6fw6q 3378 5 limited limited JJ cord-006870-f5w6fw6q 3378 6 literature literature NN cord-006870-f5w6fw6q 3378 7 that that WDT cord-006870-f5w6fw6q 3378 8 has have VBZ cord-006870-f5w6fw6q 3378 9 evaluated evaluate VBN cord-006870-f5w6fw6q 3378 10 and and CC cord-006870-f5w6fw6q 3378 11 discussed discuss VBN cord-006870-f5w6fw6q 3378 12 the the DT cord-006870-f5w6fw6q 3378 13 benefits benefit NNS cord-006870-f5w6fw6q 3378 14 and and CC cord-006870-f5w6fw6q 3378 15 potential potential JJ cord-006870-f5w6fw6q 3378 16 adverse adverse JJ cord-006870-f5w6fw6q 3378 17 effects effect NNS cord-006870-f5w6fw6q 3378 18 related relate VBN cord-006870-f5w6fw6q 3378 19 to to IN cord-006870-f5w6fw6q 3378 20 repeated repeat VBN cord-006870-f5w6fw6q 3378 21 painful painful JJ cord-006870-f5w6fw6q 3378 22 stimulation stimulation NN cord-006870-f5w6fw6q 3378 23 during during IN cord-006870-f5w6fw6q 3378 24 bedside bedside JJ cord-006870-f5w6fw6q 3378 25 neurological neurological JJ cord-006870-f5w6fw6q 3378 26 examinations examination NNS cord-006870-f5w6fw6q 3378 27 . . . cord-006870-f5w6fw6q 3379 1 Though though IN cord-006870-f5w6fw6q 3379 2 providers provider NNS cord-006870-f5w6fw6q 3379 3 intend intend VBP cord-006870-f5w6fw6q 3379 4 to to TO cord-006870-f5w6fw6q 3379 5 do do VB cord-006870-f5w6fw6q 3379 6 no no DT cord-006870-f5w6fw6q 3379 7 harm harm NN cord-006870-f5w6fw6q 3379 8 , , , cord-006870-f5w6fw6q 3379 9 the the DT cord-006870-f5w6fw6q 3379 10 practice practice NN cord-006870-f5w6fw6q 3379 11 of of IN cord-006870-f5w6fw6q 3379 12 repetitive repetitive JJ cord-006870-f5w6fw6q 3379 13 painful painful JJ cord-006870-f5w6fw6q 3379 14 stimulation stimulation NN cord-006870-f5w6fw6q 3379 15 can can MD cord-006870-f5w6fw6q 3379 16 unintentionally unintentionally RB cord-006870-f5w6fw6q 3379 17 damage damage VB cord-006870-f5w6fw6q 3379 18 patient patient NN cord-006870-f5w6fw6q 3379 19 's 's POS cord-006870-f5w6fw6q 3379 20 skin skin NN cord-006870-f5w6fw6q 3379 21 , , , cord-006870-f5w6fw6q 3379 22 muscle muscle NN cord-006870-f5w6fw6q 3379 23 , , , cord-006870-f5w6fw6q 3379 24 and and CC cord-006870-f5w6fw6q 3379 25 bone bone NN cord-006870-f5w6fw6q 3379 26 , , , cord-006870-f5w6fw6q 3379 27 as as RB cord-006870-f5w6fw6q 3379 28 well well RB cord-006870-f5w6fw6q 3379 29 as as IN cord-006870-f5w6fw6q 3379 30 inflict inflict VB cord-006870-f5w6fw6q 3379 31 emotional emotional JJ cord-006870-f5w6fw6q 3379 32 duress duress NN cord-006870-f5w6fw6q 3379 33 . . . cord-006870-f5w6fw6q 3380 1 In in IN cord-006870-f5w6fw6q 3380 2 conjunction conjunction NN cord-006870-f5w6fw6q 3380 3 with with IN cord-006870-f5w6fw6q 3380 4 basic basic JJ cord-006870-f5w6fw6q 3380 5 ethical ethical JJ cord-006870-f5w6fw6q 3380 6 principles principle NNS cord-006870-f5w6fw6q 3380 7 used use VBN cord-006870-f5w6fw6q 3380 8 to to TO cord-006870-f5w6fw6q 3380 9 justify justify VB cord-006870-f5w6fw6q 3380 10 painful painful JJ cord-006870-f5w6fw6q 3380 11 stimulation stimulation NN cord-006870-f5w6fw6q 3380 12 during during IN cord-006870-f5w6fw6q 3380 13 patient patient JJ cord-006870-f5w6fw6q 3380 14 examinations examination NNS cord-006870-f5w6fw6q 3380 15 , , , cord-006870-f5w6fw6q 3380 16 we -PRON- PRP cord-006870-f5w6fw6q 3380 17 propose propose VBP cord-006870-f5w6fw6q 3380 18 a a DT cord-006870-f5w6fw6q 3380 19 revisiting revisiting NN cord-006870-f5w6fw6q 3380 20 of of IN cord-006870-f5w6fw6q 3380 21 the the DT cord-006870-f5w6fw6q 3380 22 practice practice NN cord-006870-f5w6fw6q 3380 23 of of IN cord-006870-f5w6fw6q 3380 24 routine routine JJ cord-006870-f5w6fw6q 3380 25 repetitive repetitive JJ cord-006870-f5w6fw6q 3380 26 painful painful JJ cord-006870-f5w6fw6q 3380 27 stimulation stimulation NN cord-006870-f5w6fw6q 3380 28 in in IN cord-006870-f5w6fw6q 3380 29 neurologic neurologic JJ cord-006870-f5w6fw6q 3380 30 bedside bedside NN cord-006870-f5w6fw6q 3380 31 assessments assessment NNS cord-006870-f5w6fw6q 3380 32 . . . cord-006870-f5w6fw6q 3381 1 1 1 LS cord-006870-f5w6fw6q 3381 2 . . . cord-006870-f5w6fw6q 3382 1 Discuss discuss VB cord-006870-f5w6fw6q 3382 2 the the DT cord-006870-f5w6fw6q 3382 3 current current JJ cord-006870-f5w6fw6q 3382 4 literature literature NN cord-006870-f5w6fw6q 3382 5 regarding regard VBG cord-006870-f5w6fw6q 3382 6 the the DT cord-006870-f5w6fw6q 3382 7 use use NN cord-006870-f5w6fw6q 3382 8 of of IN cord-006870-f5w6fw6q 3382 9 painful painful JJ cord-006870-f5w6fw6q 3382 10 stimulation stimulation NN cord-006870-f5w6fw6q 3382 11 and and CC cord-006870-f5w6fw6q 3382 12 its -PRON- PRP$ cord-006870-f5w6fw6q 3382 13 beneficial beneficial JJ cord-006870-f5w6fw6q 3382 14 and and CC cord-006870-f5w6fw6q 3382 15 damaging damaging JJ cord-006870-f5w6fw6q 3382 16 effects effect NNS cord-006870-f5w6fw6q 3382 17 , , , cord-006870-f5w6fw6q 3382 18 2 2 CD cord-006870-f5w6fw6q 3382 19 . . . cord-006870-f5w6fw6q 3383 1 Describe describe VB cord-006870-f5w6fw6q 3383 2 alternative alternative JJ cord-006870-f5w6fw6q 3383 3 strategies strategy NNS cord-006870-f5w6fw6q 3383 4 for for IN cord-006870-f5w6fw6q 3383 5 neurologic neurologic JJ cord-006870-f5w6fw6q 3383 6 assessments assessment NNS cord-006870-f5w6fw6q 3383 7 , , , cord-006870-f5w6fw6q 3383 8 3 3 CD cord-006870-f5w6fw6q 3383 9 . . . cord-006870-f5w6fw6q 3384 1 Propose propose VB cord-006870-f5w6fw6q 3384 2 guidelines guideline NNS cord-006870-f5w6fw6q 3384 3 to to TO cord-006870-f5w6fw6q 3384 4 optimize optimize VB cord-006870-f5w6fw6q 3384 5 accurate accurate JJ cord-006870-f5w6fw6q 3384 6 neurologic neurologic JJ cord-006870-f5w6fw6q 3384 7 assessments assessment NNS cord-006870-f5w6fw6q 3384 8 while while IN cord-006870-f5w6fw6q 3384 9 avoiding avoid VBG cord-006870-f5w6fw6q 3384 10 unnecessary unnecessary JJ cord-006870-f5w6fw6q 3384 11 repeated repeat VBN cord-006870-f5w6fw6q 3384 12 painful painful JJ cord-006870-f5w6fw6q 3384 13 stimulation stimulation NN cord-006870-f5w6fw6q 3384 14 , , , cord-006870-f5w6fw6q 3384 15 4 4 CD cord-006870-f5w6fw6q 3384 16 . . . cord-006870-f5w6fw6q 3385 1 Propose propose VB cord-006870-f5w6fw6q 3385 2 the the DT cord-006870-f5w6fw6q 3385 3 development development NN cord-006870-f5w6fw6q 3385 4 of of IN cord-006870-f5w6fw6q 3385 5 a a DT cord-006870-f5w6fw6q 3385 6 graded grade VBN cord-006870-f5w6fw6q 3385 7 methodology methodology NN cord-006870-f5w6fw6q 3385 8 for for IN cord-006870-f5w6fw6q 3385 9 delivering deliver VBG cord-006870-f5w6fw6q 3385 10 painful painful JJ cord-006870-f5w6fw6q 3385 11 stimulation stimulation NN cord-006870-f5w6fw6q 3385 12 when when WRB cord-006870-f5w6fw6q 3385 13 necessary necessary JJ cord-006870-f5w6fw6q 3385 14 for for IN cord-006870-f5w6fw6q 3385 15 neurologic neurologic JJ cord-006870-f5w6fw6q 3385 16 assessments assessment NNS cord-006870-f5w6fw6q 3385 17 . . . cord-006870-f5w6fw6q 3386 1 A a DT cord-006870-f5w6fw6q 3386 2 summary summary NN cord-006870-f5w6fw6q 3386 3 of of IN cord-006870-f5w6fw6q 3386 4 the the DT cord-006870-f5w6fw6q 3386 5 literature literature NN cord-006870-f5w6fw6q 3386 6 will will MD cord-006870-f5w6fw6q 3386 7 be be VB cord-006870-f5w6fw6q 3386 8 outlined outline VBN cord-006870-f5w6fw6q 3386 9 and and CC cord-006870-f5w6fw6q 3386 10 discussed discuss VBN cord-006870-f5w6fw6q 3386 11 focusing focus VBG cord-006870-f5w6fw6q 3386 12 on on IN cord-006870-f5w6fw6q 3386 13 the the DT cord-006870-f5w6fw6q 3386 14 ethical ethical JJ cord-006870-f5w6fw6q 3386 15 considerations consideration NNS cord-006870-f5w6fw6q 3386 16 and and CC cord-006870-f5w6fw6q 3386 17 justification justification NN cord-006870-f5w6fw6q 3386 18 for for IN cord-006870-f5w6fw6q 3386 19 the the DT cord-006870-f5w6fw6q 3386 20 use use NN cord-006870-f5w6fw6q 3386 21 of of IN cord-006870-f5w6fw6q 3386 22 painful painful JJ cord-006870-f5w6fw6q 3386 23 stimulation stimulation NN cord-006870-f5w6fw6q 3386 24 in in IN cord-006870-f5w6fw6q 3386 25 the the DT cord-006870-f5w6fw6q 3386 26 neurologic neurologic JJ cord-006870-f5w6fw6q 3386 27 patient patient NN cord-006870-f5w6fw6q 3386 28 and and CC cord-006870-f5w6fw6q 3386 29 the the DT cord-006870-f5w6fw6q 3386 30 perception perception NN cord-006870-f5w6fw6q 3386 31 of of IN cord-006870-f5w6fw6q 3386 32 pain pain NN cord-006870-f5w6fw6q 3386 33 in in IN cord-006870-f5w6fw6q 3386 34 coma coma NN cord-006870-f5w6fw6q 3386 35 and and CC cord-006870-f5w6fw6q 3386 36 minimally minimally RB cord-006870-f5w6fw6q 3386 37 unconscious unconscious JJ cord-006870-f5w6fw6q 3386 38 patients patient NNS cord-006870-f5w6fw6q 3386 39 , , , cord-006870-f5w6fw6q 3386 40 2 2 CD cord-006870-f5w6fw6q 3386 41 . . . cord-006870-f5w6fw6q 3387 1 Alternative alternative JJ cord-006870-f5w6fw6q 3387 2 strategies strategy NNS cord-006870-f5w6fw6q 3387 3 will will MD cord-006870-f5w6fw6q 3387 4 be be VB cord-006870-f5w6fw6q 3387 5 presented present VBN cord-006870-f5w6fw6q 3387 6 to to TO cord-006870-f5w6fw6q 3387 7 minimize minimize VB cord-006870-f5w6fw6q 3387 8 bodily bodily JJ cord-006870-f5w6fw6q 3387 9 and and CC cord-006870-f5w6fw6q 3387 10 emotional emotional JJ cord-006870-f5w6fw6q 3387 11 injury injury NN cord-006870-f5w6fw6q 3387 12 , , , cord-006870-f5w6fw6q 3387 13 3 3 CD cord-006870-f5w6fw6q 3387 14 . . . cord-006870-f5w6fw6q 3388 1 A a DT cord-006870-f5w6fw6q 3388 2 proposed propose VBN cord-006870-f5w6fw6q 3388 3 outline outline NN cord-006870-f5w6fw6q 3388 4 with with IN cord-006870-f5w6fw6q 3388 5 a a DT cord-006870-f5w6fw6q 3388 6 companion companion NN cord-006870-f5w6fw6q 3388 7 flow flow NN cord-006870-f5w6fw6q 3388 8 diagram diagram NN cord-006870-f5w6fw6q 3388 9 " " `` cord-006870-f5w6fw6q 3388 10 Easing ease VBG cord-006870-f5w6fw6q 3388 11 the the DT cord-006870-f5w6fw6q 3388 12 Pain Pain NNP cord-006870-f5w6fw6q 3388 13 Guidelines Guidelines NNPS cord-006870-f5w6fw6q 3388 14 " " '' cord-006870-f5w6fw6q 3388 15 implemented implement VBN cord-006870-f5w6fw6q 3388 16 in in IN cord-006870-f5w6fw6q 3388 17 a a DT cord-006870-f5w6fw6q 3388 18 tertiary tertiary JJ cord-006870-f5w6fw6q 3388 19 care care NN cord-006870-f5w6fw6q 3388 20 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3388 21 care care NN cord-006870-f5w6fw6q 3388 22 unit unit NN cord-006870-f5w6fw6q 3388 23 will will MD cord-006870-f5w6fw6q 3388 24 be be VB cord-006870-f5w6fw6q 3388 25 presented present VBN cord-006870-f5w6fw6q 3388 26 . . . cord-006870-f5w6fw6q 3389 1 There there EX cord-006870-f5w6fw6q 3389 2 has have VBZ cord-006870-f5w6fw6q 3389 3 been be VBN cord-006870-f5w6fw6q 3389 4 little little JJ cord-006870-f5w6fw6q 3389 5 attention attention NN cord-006870-f5w6fw6q 3389 6 paid pay VBN cord-006870-f5w6fw6q 3389 7 to to IN cord-006870-f5w6fw6q 3389 8 the the DT cord-006870-f5w6fw6q 3389 9 burden burden NN cord-006870-f5w6fw6q 3389 10 of of IN cord-006870-f5w6fw6q 3389 11 painful painful JJ cord-006870-f5w6fw6q 3389 12 stimulation stimulation NN cord-006870-f5w6fw6q 3389 13 inflicted inflict VBN cord-006870-f5w6fw6q 3389 14 on on IN cord-006870-f5w6fw6q 3389 15 patients patient NNS cord-006870-f5w6fw6q 3389 16 in in IN cord-006870-f5w6fw6q 3389 17 the the DT cord-006870-f5w6fw6q 3389 18 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3389 19 care care NNP cord-006870-f5w6fw6q 3389 20 unit unit NN cord-006870-f5w6fw6q 3389 21 . . . cord-006870-f5w6fw6q 3390 1 The the DT cord-006870-f5w6fw6q 3390 2 guiding guide VBG cord-006870-f5w6fw6q 3390 3 principle principle NN cord-006870-f5w6fw6q 3390 4 of of IN cord-006870-f5w6fw6q 3390 5 nonmaleficence nonmaleficence NNP cord-006870-f5w6fw6q 3390 6 ( ( -LRB- cord-006870-f5w6fw6q 3390 7 do do VB cord-006870-f5w6fw6q 3390 8 no no DT cord-006870-f5w6fw6q 3390 9 harm harm NN cord-006870-f5w6fw6q 3390 10 ) ) -RRB- cord-006870-f5w6fw6q 3390 11 morally morally RB cord-006870-f5w6fw6q 3390 12 obligates obligate VBZ cord-006870-f5w6fw6q 3390 13 clinicians clinician NNS cord-006870-f5w6fw6q 3390 14 to to TO cord-006870-f5w6fw6q 3390 15 evaluate evaluate VB cord-006870-f5w6fw6q 3390 16 current current JJ cord-006870-f5w6fw6q 3390 17 practice practice NN cord-006870-f5w6fw6q 3390 18 standards standard NNS cord-006870-f5w6fw6q 3390 19 using use VBG cord-006870-f5w6fw6q 3390 20 repetitive repetitive JJ cord-006870-f5w6fw6q 3390 21 painful painful JJ cord-006870-f5w6fw6q 3390 22 stimulation stimulation NN cord-006870-f5w6fw6q 3390 23 in in IN cord-006870-f5w6fw6q 3390 24 routine routine JJ cord-006870-f5w6fw6q 3390 25 neurologic neurologic JJ cord-006870-f5w6fw6q 3390 26 assessments assessment NNS cord-006870-f5w6fw6q 3390 27 . . . cord-006870-f5w6fw6q 3391 1 Implementing implement VBG cord-006870-f5w6fw6q 3391 2 standardized standardized JJ cord-006870-f5w6fw6q 3391 3 guidelines guideline NNS cord-006870-f5w6fw6q 3391 4 will will MD cord-006870-f5w6fw6q 3391 5 limit limit VB cord-006870-f5w6fw6q 3391 6 unintended unintended JJ cord-006870-f5w6fw6q 3391 7 harm harm NN cord-006870-f5w6fw6q 3391 8 to to IN cord-006870-f5w6fw6q 3391 9 patients patient NNS cord-006870-f5w6fw6q 3391 10 without without IN cord-006870-f5w6fw6q 3391 11 compromising compromise VBG cord-006870-f5w6fw6q 3391 12 accurate accurate JJ cord-006870-f5w6fw6q 3391 13 neurologic neurologic JJ cord-006870-f5w6fw6q 3391 14 assessments assessment NNS cord-006870-f5w6fw6q 3391 15 . . . cord-006870-f5w6fw6q 3392 1 Plasmapheresis Plasmapheresis NNP cord-006870-f5w6fw6q 3392 2 is be VBZ cord-006870-f5w6fw6q 3392 3 utilized utilize VBN cord-006870-f5w6fw6q 3392 4 in in IN cord-006870-f5w6fw6q 3392 5 anti anti JJ cord-006870-f5w6fw6q 3392 6 - - JJ cord-006870-f5w6fw6q 3392 7 N n JJ cord-006870-f5w6fw6q 3392 8 - - HYPH cord-006870-f5w6fw6q 3392 9 methyl methyl NN cord-006870-f5w6fw6q 3392 10 - - HYPH cord-006870-f5w6fw6q 3392 11 D d NN cord-006870-f5w6fw6q 3392 12 - - HYPH cord-006870-f5w6fw6q 3392 13 aspartate aspartate NN cord-006870-f5w6fw6q 3392 14 receptor receptor NN cord-006870-f5w6fw6q 3392 15 ( ( -LRB- cord-006870-f5w6fw6q 3392 16 NMDAr NMDAr NNS cord-006870-f5w6fw6q 3392 17 ) ) -RRB- cord-006870-f5w6fw6q 3392 18 encephalitis encephalitis JJ cord-006870-f5w6fw6q 3392 19 to to TO cord-006870-f5w6fw6q 3392 20 remove remove VB cord-006870-f5w6fw6q 3392 21 autoantibodies autoantibody NNS cord-006870-f5w6fw6q 3392 22 . . . cord-006870-f5w6fw6q 3393 1 Antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 3393 2 drugs drug NNS cord-006870-f5w6fw6q 3393 3 ( ( -LRB- cord-006870-f5w6fw6q 3393 4 AED AED NNP cord-006870-f5w6fw6q 3393 5 ) ) -RRB- cord-006870-f5w6fw6q 3393 6 , , , cord-006870-f5w6fw6q 3393 7 such such JJ cord-006870-f5w6fw6q 3393 8 as as IN cord-006870-f5w6fw6q 3393 9 valproate valproate RB cord-006870-f5w6fw6q 3393 10 , , , cord-006870-f5w6fw6q 3393 11 are be VBP cord-006870-f5w6fw6q 3393 12 often often RB cord-006870-f5w6fw6q 3393 13 used use VBN cord-006870-f5w6fw6q 3393 14 to to TO cord-006870-f5w6fw6q 3393 15 control control VB cord-006870-f5w6fw6q 3393 16 seizures seizure NNS cord-006870-f5w6fw6q 3393 17 which which WDT cord-006870-f5w6fw6q 3393 18 may may MD cord-006870-f5w6fw6q 3393 19 complicate complicate VB cord-006870-f5w6fw6q 3393 20 anti anti JJ cord-006870-f5w6fw6q 3393 21 - - NNS cord-006870-f5w6fw6q 3393 22 NMDAr nmdar JJ cord-006870-f5w6fw6q 3393 23 encephalitis encephalitis RB cord-006870-f5w6fw6q 3393 24 . . . cord-006870-f5w6fw6q 3394 1 It -PRON- PRP cord-006870-f5w6fw6q 3394 2 is be VBZ cord-006870-f5w6fw6q 3394 3 important important JJ cord-006870-f5w6fw6q 3394 4 to to TO cord-006870-f5w6fw6q 3394 5 prevent prevent VB cord-006870-f5w6fw6q 3394 6 rapid rapid JJ cord-006870-f5w6fw6q 3394 7 reductions reduction NNS cord-006870-f5w6fw6q 3394 8 of of IN cord-006870-f5w6fw6q 3394 9 AED AED NNP cord-006870-f5w6fw6q 3394 10 levels level NNS cord-006870-f5w6fw6q 3394 11 to to TO cord-006870-f5w6fw6q 3394 12 ensure ensure VB cord-006870-f5w6fw6q 3394 13 proper proper JJ cord-006870-f5w6fw6q 3394 14 seizure seizure NN cord-006870-f5w6fw6q 3394 15 management management NN cord-006870-f5w6fw6q 3394 16 in in IN cord-006870-f5w6fw6q 3394 17 this this DT cord-006870-f5w6fw6q 3394 18 setting setting NN cord-006870-f5w6fw6q 3394 19 . . . cord-006870-f5w6fw6q 3395 1 We -PRON- PRP cord-006870-f5w6fw6q 3395 2 obtained obtain VBD cord-006870-f5w6fw6q 3395 3 total total JJ cord-006870-f5w6fw6q 3395 4 and and CC cord-006870-f5w6fw6q 3395 5 free free JJ cord-006870-f5w6fw6q 3395 6 ( ( -LRB- cord-006870-f5w6fw6q 3395 7 active active JJ cord-006870-f5w6fw6q 3395 8 drug drug NN cord-006870-f5w6fw6q 3395 9 , , , cord-006870-f5w6fw6q 3395 10 unbound unbound JJ cord-006870-f5w6fw6q 3395 11 to to IN cord-006870-f5w6fw6q 3395 12 plasma plasma NN cord-006870-f5w6fw6q 3395 13 proteins protein NNS cord-006870-f5w6fw6q 3395 14 ) ) -RRB- cord-006870-f5w6fw6q 3395 15 valproate valproate RB cord-006870-f5w6fw6q 3395 16 levels level NNS cord-006870-f5w6fw6q 3395 17 intermittently intermittently RB cord-006870-f5w6fw6q 3395 18 throughout throughout IN cord-006870-f5w6fw6q 3395 19 two two CD cord-006870-f5w6fw6q 3395 20 5-day 5-day JJ cord-006870-f5w6fw6q 3395 21 courses course NNS cord-006870-f5w6fw6q 3395 22 of of IN cord-006870-f5w6fw6q 3395 23 daily daily JJ cord-006870-f5w6fw6q 3395 24 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3395 25 . . . cord-006870-f5w6fw6q 3396 1 During during IN cord-006870-f5w6fw6q 3396 2 the the DT cord-006870-f5w6fw6q 3396 3 first first JJ cord-006870-f5w6fw6q 3396 4 course course NN cord-006870-f5w6fw6q 3396 5 , , , cord-006870-f5w6fw6q 3396 6 trough trough NN cord-006870-f5w6fw6q 3396 7 levels level NNS cord-006870-f5w6fw6q 3396 8 were be VBD cord-006870-f5w6fw6q 3396 9 obtained obtain VBN cord-006870-f5w6fw6q 3396 10 . . . cord-006870-f5w6fw6q 3397 1 During during IN cord-006870-f5w6fw6q 3397 2 the the DT cord-006870-f5w6fw6q 3397 3 second second JJ cord-006870-f5w6fw6q 3397 4 course course NN cord-006870-f5w6fw6q 3397 5 , , , cord-006870-f5w6fw6q 3397 6 levels level NNS cord-006870-f5w6fw6q 3397 7 were be VBD cord-006870-f5w6fw6q 3397 8 obtained obtain VBN cord-006870-f5w6fw6q 3397 9 before before RB cord-006870-f5w6fw6q 3397 10 , , , cord-006870-f5w6fw6q 3397 11 during during IN cord-006870-f5w6fw6q 3397 12 , , , cord-006870-f5w6fw6q 3397 13 and and CC cord-006870-f5w6fw6q 3397 14 after after IN cord-006870-f5w6fw6q 3397 15 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3397 16 . . . cord-006870-f5w6fw6q 3398 1 The the DT cord-006870-f5w6fw6q 3398 2 patient patient NN cord-006870-f5w6fw6q 3398 3 was be VBD cord-006870-f5w6fw6q 3398 4 a a DT cord-006870-f5w6fw6q 3398 5 26 26 CD cord-006870-f5w6fw6q 3398 6 year year NN cord-006870-f5w6fw6q 3398 7 old old JJ cord-006870-f5w6fw6q 3398 8 female female NN cord-006870-f5w6fw6q 3398 9 , , , cord-006870-f5w6fw6q 3398 10 weighing weigh VBG cord-006870-f5w6fw6q 3398 11 79 79 CD cord-006870-f5w6fw6q 3398 12 kg kg NNS cord-006870-f5w6fw6q 3398 13 . . . cord-006870-f5w6fw6q 3399 1 Albumin albumin NN cord-006870-f5w6fw6q 3399 2 was be VBD cord-006870-f5w6fw6q 3399 3 2.6 2.6 CD cord-006870-f5w6fw6q 3399 4 g g NN cord-006870-f5w6fw6q 3399 5 / / SYM cord-006870-f5w6fw6q 3399 6 dL. dl. NN cord-006870-f5w6fw6q 3400 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 3400 2 valproate valproate JJ cord-006870-f5w6fw6q 3400 3 regimen regimen NN cord-006870-f5w6fw6q 3400 4 ranged range VBD cord-006870-f5w6fw6q 3400 5 from from IN cord-006870-f5w6fw6q 3400 6 1250 1250 CD cord-006870-f5w6fw6q 3400 7 mg mg NN cord-006870-f5w6fw6q 3400 8 to to IN cord-006870-f5w6fw6q 3400 9 2250 2250 CD cord-006870-f5w6fw6q 3400 10 mg mg NN cord-006870-f5w6fw6q 3400 11 every every DT cord-006870-f5w6fw6q 3400 12 8 8 CD cord-006870-f5w6fw6q 3400 13 hours hour NNS cord-006870-f5w6fw6q 3400 14 ( ( -LRB- cord-006870-f5w6fw6q 3400 15 47 47 CD cord-006870-f5w6fw6q 3400 16 to to TO cord-006870-f5w6fw6q 3400 17 85 85 CD cord-006870-f5w6fw6q 3400 18 mg mg NNP cord-006870-f5w6fw6q 3400 19 / / SYM cord-006870-f5w6fw6q 3400 20 kg kg NNP cord-006870-f5w6fw6q 3400 21 / / SYM cord-006870-f5w6fw6q 3400 22 day day NN cord-006870-f5w6fw6q 3400 23 ) ) -RRB- cord-006870-f5w6fw6q 3400 24 , , , cord-006870-f5w6fw6q 3400 25 given give VBN cord-006870-f5w6fw6q 3400 26 intravenously intravenously RB cord-006870-f5w6fw6q 3400 27 or or CC cord-006870-f5w6fw6q 3400 28 enterally enterally RB cord-006870-f5w6fw6q 3400 29 . . . cord-006870-f5w6fw6q 3401 1 Prior prior RB cord-006870-f5w6fw6q 3401 2 to to IN cord-006870-f5w6fw6q 3401 3 the the DT cord-006870-f5w6fw6q 3401 4 first first JJ cord-006870-f5w6fw6q 3401 5 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3401 6 , , , cord-006870-f5w6fw6q 3401 7 valproate valproate RB cord-006870-f5w6fw6q 3401 8 dose dose NN cord-006870-f5w6fw6q 3401 9 was be VBD cord-006870-f5w6fw6q 3401 10 1250 1250 CD cord-006870-f5w6fw6q 3401 11 mg mg NN cord-006870-f5w6fw6q 3401 12 every every DT cord-006870-f5w6fw6q 3401 13 8 8 CD cord-006870-f5w6fw6q 3401 14 hours hour NNS cord-006870-f5w6fw6q 3401 15 , , , cord-006870-f5w6fw6q 3401 16 resulting result VBG cord-006870-f5w6fw6q 3401 17 in in IN cord-006870-f5w6fw6q 3401 18 a a DT cord-006870-f5w6fw6q 3401 19 total total JJ cord-006870-f5w6fw6q 3401 20 level level NN cord-006870-f5w6fw6q 3401 21 of of IN cord-006870-f5w6fw6q 3401 22 25 25 CD cord-006870-f5w6fw6q 3401 23 mcg mcg NN cord-006870-f5w6fw6q 3401 24 / / SYM cord-006870-f5w6fw6q 3401 25 mL ml NN cord-006870-f5w6fw6q 3401 26 ( ( -LRB- cord-006870-f5w6fw6q 3401 27 reference reference NN cord-006870-f5w6fw6q 3401 28 range range NN cord-006870-f5w6fw6q 3401 29 : : : cord-006870-f5w6fw6q 3401 30 50 50 CD cord-006870-f5w6fw6q 3401 31 - - SYM cord-006870-f5w6fw6q 3401 32 125 125 CD cord-006870-f5w6fw6q 3401 33 mcg mcg NN cord-006870-f5w6fw6q 3401 34 / / SYM cord-006870-f5w6fw6q 3401 35 mL mL NNP cord-006870-f5w6fw6q 3401 36 ) ) -RRB- cord-006870-f5w6fw6q 3401 37 . . . cord-006870-f5w6fw6q 3402 1 Free free JJ cord-006870-f5w6fw6q 3402 2 valproate valproate NN cord-006870-f5w6fw6q 3402 3 was be VBD cord-006870-f5w6fw6q 3402 4 21 21 CD cord-006870-f5w6fw6q 3402 5 mcg mcg NN cord-006870-f5w6fw6q 3402 6 / / SYM cord-006870-f5w6fw6q 3402 7 mL ml NN cord-006870-f5w6fw6q 3402 8 ( ( -LRB- cord-006870-f5w6fw6q 3402 9 reference reference NN cord-006870-f5w6fw6q 3402 10 range range NN cord-006870-f5w6fw6q 3402 11 : : : cord-006870-f5w6fw6q 3402 12 7 7 CD cord-006870-f5w6fw6q 3402 13 - - SYM cord-006870-f5w6fw6q 3402 14 23 23 CD cord-006870-f5w6fw6q 3402 15 mcg mcg NNP cord-006870-f5w6fw6q 3402 16 / / SYM cord-006870-f5w6fw6q 3402 17 mL mL NNP cord-006870-f5w6fw6q 3402 18 ) ) -RRB- cord-006870-f5w6fw6q 3402 19 ; ; , cord-006870-f5w6fw6q 3402 20 free free JJ cord-006870-f5w6fw6q 3402 21 fraction fraction NN cord-006870-f5w6fw6q 3402 22 was be VBD cord-006870-f5w6fw6q 3402 23 86 86 CD cord-006870-f5w6fw6q 3402 24 % % NN cord-006870-f5w6fw6q 3402 25 ( ( -LRB- cord-006870-f5w6fw6q 3402 26 reference reference NN cord-006870-f5w6fw6q 3402 27 range range NN cord-006870-f5w6fw6q 3402 28 : : : cord-006870-f5w6fw6q 3402 29 5 5 CD cord-006870-f5w6fw6q 3402 30 - - SYM cord-006870-f5w6fw6q 3402 31 18 18 CD cord-006870-f5w6fw6q 3402 32 % % NN cord-006870-f5w6fw6q 3402 33 ) ) -RRB- cord-006870-f5w6fw6q 3402 34 . . . cord-006870-f5w6fw6q 3403 1 Four four CD cord-006870-f5w6fw6q 3403 2 days day NNS cord-006870-f5w6fw6q 3403 3 later later RB cord-006870-f5w6fw6q 3403 4 , , , cord-006870-f5w6fw6q 3403 5 prior prior RB cord-006870-f5w6fw6q 3403 6 to to IN cord-006870-f5w6fw6q 3403 7 the the DT cord-006870-f5w6fw6q 3403 8 5th 5th JJ cord-006870-f5w6fw6q 3403 9 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3403 10 , , , cord-006870-f5w6fw6q 3403 11 the the DT cord-006870-f5w6fw6q 3403 12 total total JJ cord-006870-f5w6fw6q 3403 13 valproate valproate JJ cord-006870-f5w6fw6q 3403 14 level level NN cord-006870-f5w6fw6q 3403 15 was be VBD cord-006870-f5w6fw6q 3403 16 35.3 35.3 CD cord-006870-f5w6fw6q 3403 17 mcg mcg NNP cord-006870-f5w6fw6q 3403 18 / / SYM cord-006870-f5w6fw6q 3403 19 mL. mL. NNP cord-006870-f5w6fw6q 3403 20 Two two CD cord-006870-f5w6fw6q 3403 21 days day NNS cord-006870-f5w6fw6q 3403 22 after after IN cord-006870-f5w6fw6q 3403 23 the the DT cord-006870-f5w6fw6q 3403 24 5th 5th JJ cord-006870-f5w6fw6q 3403 25 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3403 26 the the DT cord-006870-f5w6fw6q 3403 27 total total JJ cord-006870-f5w6fw6q 3403 28 level level NN cord-006870-f5w6fw6q 3403 29 was be VBD cord-006870-f5w6fw6q 3403 30 unchanged unchanged JJ cord-006870-f5w6fw6q 3403 31 at at IN cord-006870-f5w6fw6q 3403 32 34 34 CD cord-006870-f5w6fw6q 3403 33 mcg mcg NN cord-006870-f5w6fw6q 3403 34 / / SYM cord-006870-f5w6fw6q 3403 35 mL ml NN cord-006870-f5w6fw6q 3403 36 ; ; : cord-006870-f5w6fw6q 3403 37 free free JJ cord-006870-f5w6fw6q 3403 38 valproate valproate NN cord-006870-f5w6fw6q 3403 39 was be VBD cord-006870-f5w6fw6q 3403 40 8 8 CD cord-006870-f5w6fw6q 3403 41 mcg mcg NN cord-006870-f5w6fw6q 3403 42 / / SYM cord-006870-f5w6fw6q 3403 43 mL ml NN cord-006870-f5w6fw6q 3403 44 and and CC cord-006870-f5w6fw6q 3403 45 free free JJ cord-006870-f5w6fw6q 3403 46 fraction fraction NN cord-006870-f5w6fw6q 3403 47 was be VBD cord-006870-f5w6fw6q 3403 48 24 24 CD cord-006870-f5w6fw6q 3403 49 % % NN cord-006870-f5w6fw6q 3403 50 . . . cord-006870-f5w6fw6q 3404 1 During during IN cord-006870-f5w6fw6q 3404 2 the the DT cord-006870-f5w6fw6q 3404 3 second second JJ cord-006870-f5w6fw6q 3404 4 course course NN cord-006870-f5w6fw6q 3404 5 of of IN cord-006870-f5w6fw6q 3404 6 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3404 7 , , , cord-006870-f5w6fw6q 3404 8 valproate valproate RB cord-006870-f5w6fw6q 3404 9 total total JJ cord-006870-f5w6fw6q 3404 10 levels level NNS cord-006870-f5w6fw6q 3404 11 , , , cord-006870-f5w6fw6q 3404 12 free free JJ cord-006870-f5w6fw6q 3404 13 levels level NNS cord-006870-f5w6fw6q 3404 14 , , , cord-006870-f5w6fw6q 3404 15 and and CC cord-006870-f5w6fw6q 3404 16 free free JJ cord-006870-f5w6fw6q 3404 17 fractions fraction NNS cord-006870-f5w6fw6q 3404 18 were be VBD cord-006870-f5w6fw6q 3404 19 49 49 CD cord-006870-f5w6fw6q 3404 20 mcg mcg NN cord-006870-f5w6fw6q 3404 21 / / SYM cord-006870-f5w6fw6q 3404 22 mL mL NNP cord-006870-f5w6fw6q 3404 23 , , , cord-006870-f5w6fw6q 3404 24 18 18 CD cord-006870-f5w6fw6q 3404 25 mcg mcg NN cord-006870-f5w6fw6q 3404 26 / / SYM cord-006870-f5w6fw6q 3404 27 mL mL NNP cord-006870-f5w6fw6q 3404 28 , , , cord-006870-f5w6fw6q 3404 29 and and CC cord-006870-f5w6fw6q 3404 30 36 36 CD cord-006870-f5w6fw6q 3404 31 % % NN cord-006870-f5w6fw6q 3404 32 before before RB cord-006870-f5w6fw6q 3404 33 , , , cord-006870-f5w6fw6q 3404 34 105 105 CD cord-006870-f5w6fw6q 3404 35 mcg mcg NN cord-006870-f5w6fw6q 3404 36 / / SYM cord-006870-f5w6fw6q 3404 37 mL mL NNP cord-006870-f5w6fw6q 3404 38 , , , cord-006870-f5w6fw6q 3404 39 24 24 CD cord-006870-f5w6fw6q 3404 40 mcg mcg NN cord-006870-f5w6fw6q 3404 41 / / SYM cord-006870-f5w6fw6q 3404 42 mL mL NNP cord-006870-f5w6fw6q 3404 43 , , , cord-006870-f5w6fw6q 3404 44 and and CC cord-006870-f5w6fw6q 3404 45 23 23 CD cord-006870-f5w6fw6q 3404 46 % % NN cord-006870-f5w6fw6q 3404 47 during during IN cord-006870-f5w6fw6q 3404 48 ( ( -LRB- cord-006870-f5w6fw6q 3404 49 valproate valproate RB cord-006870-f5w6fw6q 3404 50 dose dose NN cord-006870-f5w6fw6q 3404 51 given give VBN cord-006870-f5w6fw6q 3404 52 upon upon IN cord-006870-f5w6fw6q 3404 53 initiation initiation NN cord-006870-f5w6fw6q 3404 54 of of IN cord-006870-f5w6fw6q 3404 55 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3404 56 ) ) -RRB- cord-006870-f5w6fw6q 3404 57 , , , cord-006870-f5w6fw6q 3404 58 and and CC cord-006870-f5w6fw6q 3404 59 59 59 CD cord-006870-f5w6fw6q 3404 60 mcg mcg NN cord-006870-f5w6fw6q 3404 61 / / SYM cord-006870-f5w6fw6q 3404 62 mL mL NNP cord-006870-f5w6fw6q 3404 63 , , , cord-006870-f5w6fw6q 3404 64 24 24 CD cord-006870-f5w6fw6q 3404 65 mcg mcg NN cord-006870-f5w6fw6q 3404 66 / / SYM cord-006870-f5w6fw6q 3404 67 mL mL NNP cord-006870-f5w6fw6q 3404 68 , , , cord-006870-f5w6fw6q 3404 69 and and CC cord-006870-f5w6fw6q 3404 70 41 41 CD cord-006870-f5w6fw6q 3404 71 % % NN cord-006870-f5w6fw6q 3404 72 after after IN cord-006870-f5w6fw6q 3404 73 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3404 74 , , , cord-006870-f5w6fw6q 3404 75 respectively respectively RB cord-006870-f5w6fw6q 3404 76 . . . cord-006870-f5w6fw6q 3405 1 Valproate valproate RB cord-006870-f5w6fw6q 3405 2 serum serum NN cord-006870-f5w6fw6q 3405 3 levels level NNS cord-006870-f5w6fw6q 3405 4 were be VBD cord-006870-f5w6fw6q 3405 5 not not RB cord-006870-f5w6fw6q 3405 6 markedly markedly RB cord-006870-f5w6fw6q 3405 7 influenced influence VBN cord-006870-f5w6fw6q 3405 8 by by IN cord-006870-f5w6fw6q 3405 9 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 3405 10 . . . cord-006870-f5w6fw6q 3406 1 Free free JJ cord-006870-f5w6fw6q 3406 2 valproate valproate NN cord-006870-f5w6fw6q 3406 3 levels level NNS cord-006870-f5w6fw6q 3406 4 and and CC cord-006870-f5w6fw6q 3406 5 the the DT cord-006870-f5w6fw6q 3406 6 free free JJ cord-006870-f5w6fw6q 3406 7 fraction fraction NN cord-006870-f5w6fw6q 3406 8 were be VBD cord-006870-f5w6fw6q 3406 9 highly highly RB cord-006870-f5w6fw6q 3406 10 elevated elevated JJ cord-006870-f5w6fw6q 3406 11 throughout throughout IN cord-006870-f5w6fw6q 3406 12 the the DT cord-006870-f5w6fw6q 3406 13 patient patient NN cord-006870-f5w6fw6q 3406 14 's 's POS cord-006870-f5w6fw6q 3406 15 hospital hospital NN cord-006870-f5w6fw6q 3406 16 course course NN cord-006870-f5w6fw6q 3406 17 , , , cord-006870-f5w6fw6q 3406 18 however however RB cord-006870-f5w6fw6q 3406 19 . . . cord-006870-f5w6fw6q 3407 1 Future future JJ cord-006870-f5w6fw6q 3407 2 studies study NNS cord-006870-f5w6fw6q 3407 3 should should MD cord-006870-f5w6fw6q 3407 4 evaluate evaluate VB cord-006870-f5w6fw6q 3407 5 critically critically RB cord-006870-f5w6fw6q 3407 6 ill ill JJ cord-006870-f5w6fw6q 3407 7 patients patient NNS cord-006870-f5w6fw6q 3407 8 ' ' POS cord-006870-f5w6fw6q 3407 9 clinical clinical JJ cord-006870-f5w6fw6q 3407 10 response response NN cord-006870-f5w6fw6q 3407 11 and and CC cord-006870-f5w6fw6q 3407 12 toxicity toxicity NN cord-006870-f5w6fw6q 3407 13 correlations correlation NNS cord-006870-f5w6fw6q 3407 14 as as IN cord-006870-f5w6fw6q 3407 15 the the DT cord-006870-f5w6fw6q 3407 16 free free JJ cord-006870-f5w6fw6q 3407 17 fraction fraction NN cord-006870-f5w6fw6q 3407 18 of of IN cord-006870-f5w6fw6q 3407 19 valproate valproate NN cord-006870-f5w6fw6q 3407 20 appears appear VBZ cord-006870-f5w6fw6q 3407 21 to to TO cord-006870-f5w6fw6q 3407 22 be be VB cord-006870-f5w6fw6q 3407 23 elevated elevate VBN cord-006870-f5w6fw6q 3407 24 in in IN cord-006870-f5w6fw6q 3407 25 this this DT cord-006870-f5w6fw6q 3407 26 setting setting NN cord-006870-f5w6fw6q 3407 27 . . . cord-006870-f5w6fw6q 3408 1 The the DT cord-006870-f5w6fw6q 3408 2 purpose purpose NN cord-006870-f5w6fw6q 3408 3 of of IN cord-006870-f5w6fw6q 3408 4 this this DT cord-006870-f5w6fw6q 3408 5 study study NN cord-006870-f5w6fw6q 3408 6 is be VBZ cord-006870-f5w6fw6q 3408 7 to to TO cord-006870-f5w6fw6q 3408 8 assess assess VB cord-006870-f5w6fw6q 3408 9 knowledge knowledge NN cord-006870-f5w6fw6q 3408 10 retention retention NN cord-006870-f5w6fw6q 3408 11 of of IN cord-006870-f5w6fw6q 3408 12 Emergency Emergency NNP cord-006870-f5w6fw6q 3408 13 Neurological Neurological NNP cord-006870-f5w6fw6q 3408 14 Life Life NNP cord-006870-f5w6fw6q 3408 15 Support Support NNP cord-006870-f5w6fw6q 3408 16 ( ( -LRB- cord-006870-f5w6fw6q 3408 17 ENLS ENLS NNP cord-006870-f5w6fw6q 3408 18 ) ) -RRB- cord-006870-f5w6fw6q 3408 19 after after IN cord-006870-f5w6fw6q 3408 20 participation participation NN cord-006870-f5w6fw6q 3408 21 in in IN cord-006870-f5w6fw6q 3408 22 the the DT cord-006870-f5w6fw6q 3408 23 course course NN cord-006870-f5w6fw6q 3408 24 via via IN cord-006870-f5w6fw6q 3408 25 a a DT cord-006870-f5w6fw6q 3408 26 prospective prospective JJ cord-006870-f5w6fw6q 3408 27 observational observational JJ cord-006870-f5w6fw6q 3408 28 study study NN cord-006870-f5w6fw6q 3408 29 . . . cord-006870-f5w6fw6q 3409 1 Study study NN cord-006870-f5w6fw6q 3409 2 subjects subject NNS cord-006870-f5w6fw6q 3409 3 seeking seek VBG cord-006870-f5w6fw6q 3409 4 ENLS enl NNS cord-006870-f5w6fw6q 3409 5 certification certification NN cord-006870-f5w6fw6q 3409 6 consented consent VBD cord-006870-f5w6fw6q 3409 7 for for IN cord-006870-f5w6fw6q 3409 8 study study NN cord-006870-f5w6fw6q 3409 9 participation participation NN cord-006870-f5w6fw6q 3409 10 ( ( -LRB- cord-006870-f5w6fw6q 3409 11 ENLS ENLS NNP cord-006870-f5w6fw6q 3409 12 - - HYPH cord-006870-f5w6fw6q 3409 13 VS VS NNP cord-006870-f5w6fw6q 3409 14 ) ) -RRB- cord-006870-f5w6fw6q 3409 15 from from IN cord-006870-f5w6fw6q 3409 16 the the DT cord-006870-f5w6fw6q 3409 17 NCS NCS NNP cord-006870-f5w6fw6q 3409 18 website website NN cord-006870-f5w6fw6q 3409 19 then then RB cord-006870-f5w6fw6q 3409 20 took take VBD cord-006870-f5w6fw6q 3409 21 a a DT cord-006870-f5w6fw6q 3409 22 closed close VBN cord-006870-f5w6fw6q 3409 23 - - HYPH cord-006870-f5w6fw6q 3409 24 book book NN cord-006870-f5w6fw6q 3409 25 , , , cord-006870-f5w6fw6q 3409 26 70 70 CD cord-006870-f5w6fw6q 3409 27 multiple multiple JJ cord-006870-f5w6fw6q 3409 28 - - HYPH cord-006870-f5w6fw6q 3409 29 choice choice NN cord-006870-f5w6fw6q 3409 30 question question NN cord-006870-f5w6fw6q 3409 31 pre pre JJ cord-006870-f5w6fw6q 3409 32 - - JJ cord-006870-f5w6fw6q 3409 33 test test NN cord-006870-f5w6fw6q 3409 34 within within IN cord-006870-f5w6fw6q 3409 35 72 72 CD cord-006870-f5w6fw6q 3409 36 hours hour NNS cord-006870-f5w6fw6q 3409 37 of of IN cord-006870-f5w6fw6q 3409 38 ENLS enl NNS cord-006870-f5w6fw6q 3409 39 course course NN cord-006870-f5w6fw6q 3409 40 participation participation NN cord-006870-f5w6fw6q 3409 41 . . . cord-006870-f5w6fw6q 3410 1 After after IN cord-006870-f5w6fw6q 3410 2 completion completion NN cord-006870-f5w6fw6q 3410 3 of of IN cord-006870-f5w6fw6q 3410 4 the the DT cord-006870-f5w6fw6q 3410 5 ENLS enl NNS cord-006870-f5w6fw6q 3410 6 course course NN cord-006870-f5w6fw6q 3410 7 , , , cord-006870-f5w6fw6q 3410 8 participants participant NNS cord-006870-f5w6fw6q 3410 9 took take VBD cord-006870-f5w6fw6q 3410 10 the the DT cord-006870-f5w6fw6q 3410 11 same same JJ cord-006870-f5w6fw6q 3410 12 closed closed JJ cord-006870-f5w6fw6q 3410 13 - - HYPH cord-006870-f5w6fw6q 3410 14 book book NN cord-006870-f5w6fw6q 3410 15 , , , cord-006870-f5w6fw6q 3410 16 70 70 CD cord-006870-f5w6fw6q 3410 17 multiplechoice multiplechoice NN cord-006870-f5w6fw6q 3410 18 question question NN cord-006870-f5w6fw6q 3410 19 test test NN cord-006870-f5w6fw6q 3410 20 ( ( -LRB- cord-006870-f5w6fw6q 3410 21 post post JJ cord-006870-f5w6fw6q 3410 22 - - JJ cord-006870-f5w6fw6q 3410 23 test test JJ cord-006870-f5w6fw6q 3410 24 ) ) -RRB- cord-006870-f5w6fw6q 3410 25 . . . cord-006870-f5w6fw6q 3411 1 These these DT cord-006870-f5w6fw6q 3411 2 tests test NNS cord-006870-f5w6fw6q 3411 3 consisted consist VBD cord-006870-f5w6fw6q 3411 4 of of IN cord-006870-f5w6fw6q 3411 5 novel novel JJ cord-006870-f5w6fw6q 3411 6 questions question NNS cord-006870-f5w6fw6q 3411 7 from from IN cord-006870-f5w6fw6q 3411 8 material material NN cord-006870-f5w6fw6q 3411 9 presented present VBN cord-006870-f5w6fw6q 3411 10 in in IN cord-006870-f5w6fw6q 3411 11 the the DT cord-006870-f5w6fw6q 3411 12 course course NN cord-006870-f5w6fw6q 3411 13 . . . cord-006870-f5w6fw6q 3412 1 Questions question NNS cord-006870-f5w6fw6q 3412 2 were be VBD cord-006870-f5w6fw6q 3412 3 not not RB cord-006870-f5w6fw6q 3412 4 repeated repeat VBN cord-006870-f5w6fw6q 3412 5 from from IN cord-006870-f5w6fw6q 3412 6 the the DT cord-006870-f5w6fw6q 3412 7 ENLS enl NNS cord-006870-f5w6fw6q 3412 8 certification certification NN cord-006870-f5w6fw6q 3412 9 exams exam NNS cord-006870-f5w6fw6q 3412 10 . . . cord-006870-f5w6fw6q 3413 1 Thirty thirty CD cord-006870-f5w6fw6q 3413 2 participants participant NNS cord-006870-f5w6fw6q 3413 3 enrolled enrol VBN cord-006870-f5w6fw6q 3413 4 in in IN cord-006870-f5w6fw6q 3413 5 the the DT cord-006870-f5w6fw6q 3413 6 study study NN cord-006870-f5w6fw6q 3413 7 with with IN cord-006870-f5w6fw6q 3413 8 11 11 CD cord-006870-f5w6fw6q 3413 9 completing complete VBG cord-006870-f5w6fw6q 3413 10 both both CC cord-006870-f5w6fw6q 3413 11 the the DT cord-006870-f5w6fw6q 3413 12 pre pre JJ cord-006870-f5w6fw6q 3413 13 - - JJ cord-006870-f5w6fw6q 3413 14 test test JJ cord-006870-f5w6fw6q 3413 15 and and CC cord-006870-f5w6fw6q 3413 16 immediate immediate JJ cord-006870-f5w6fw6q 3413 17 post post NN cord-006870-f5w6fw6q 3413 18 - - JJ cord-006870-f5w6fw6q 3413 19 test test NN cord-006870-f5w6fw6q 3413 20 . . . cord-006870-f5w6fw6q 3414 1 All all DT cord-006870-f5w6fw6q 3414 2 11 11 CD cord-006870-f5w6fw6q 3414 3 participants participant NNS cord-006870-f5w6fw6q 3414 4 ' ' POS cord-006870-f5w6fw6q 3414 5 scores score NNS cord-006870-f5w6fw6q 3414 6 improved improve VBD cord-006870-f5w6fw6q 3414 7 on on IN cord-006870-f5w6fw6q 3414 8 the the DT cord-006870-f5w6fw6q 3414 9 post post NN cord-006870-f5w6fw6q 3414 10 - - JJ cord-006870-f5w6fw6q 3414 11 test test NN cord-006870-f5w6fw6q 3414 12 as as IN cord-006870-f5w6fw6q 3414 13 compared compare VBN cord-006870-f5w6fw6q 3414 14 to to IN cord-006870-f5w6fw6q 3414 15 the the DT cord-006870-f5w6fw6q 3414 16 pre pre NN cord-006870-f5w6fw6q 3414 17 - - JJ cord-006870-f5w6fw6q 3414 18 test test NN cord-006870-f5w6fw6q 3414 19 . . . cord-006870-f5w6fw6q 3415 1 The the DT cord-006870-f5w6fw6q 3415 2 mean mean JJ cord-006870-f5w6fw6q 3415 3 percent percent NN cord-006870-f5w6fw6q 3415 4 correct correct JJ cord-006870-f5w6fw6q 3415 5 on on IN cord-006870-f5w6fw6q 3415 6 the the DT cord-006870-f5w6fw6q 3415 7 pre pre JJ cord-006870-f5w6fw6q 3415 8 - - JJ cord-006870-f5w6fw6q 3415 9 test test NN cord-006870-f5w6fw6q 3415 10 was be VBD cord-006870-f5w6fw6q 3415 11 63.5 63.5 CD cord-006870-f5w6fw6q 3415 12 % % NN cord-006870-f5w6fw6q 3415 13 with with IN cord-006870-f5w6fw6q 3415 14 a a DT cord-006870-f5w6fw6q 3415 15 median median NN cord-006870-f5w6fw6q 3415 16 of of IN cord-006870-f5w6fw6q 3415 17 64.3 64.3 CD cord-006870-f5w6fw6q 3415 18 % % NN cord-006870-f5w6fw6q 3415 19 ( ( -LRB- cord-006870-f5w6fw6q 3415 20 range range NNP cord-006870-f5w6fw6q 3415 21 34.5 34.5 CD cord-006870-f5w6fw6q 3415 22 - - HYPH cord-006870-f5w6fw6q 3415 23 85.7 85.7 CD cord-006870-f5w6fw6q 3415 24 % % NN cord-006870-f5w6fw6q 3415 25 ) ) -RRB- cord-006870-f5w6fw6q 3415 26 . . . cord-006870-f5w6fw6q 3416 1 Of of IN cord-006870-f5w6fw6q 3416 2 the the DT cord-006870-f5w6fw6q 3416 3 participants participant NNS cord-006870-f5w6fw6q 3416 4 who who WP cord-006870-f5w6fw6q 3416 5 have have VBP cord-006870-f5w6fw6q 3416 6 completed complete VBN cord-006870-f5w6fw6q 3416 7 both both DT cord-006870-f5w6fw6q 3416 8 pre pre VB cord-006870-f5w6fw6q 3416 9 - - JJ cord-006870-f5w6fw6q 3416 10 and and CC cord-006870-f5w6fw6q 3416 11 immediate immediate JJ cord-006870-f5w6fw6q 3416 12 post post NN cord-006870-f5w6fw6q 3416 13 - - JJ cord-006870-f5w6fw6q 3416 14 test test JJ cord-006870-f5w6fw6q 3416 15 , , , cord-006870-f5w6fw6q 3416 16 the the DT cord-006870-f5w6fw6q 3416 17 mean mean JJ cord-006870-f5w6fw6q 3416 18 pre pre JJ cord-006870-f5w6fw6q 3416 19 - - JJ cord-006870-f5w6fw6q 3416 20 test test JJ cord-006870-f5w6fw6q 3416 21 score score NN cord-006870-f5w6fw6q 3416 22 was be VBD cord-006870-f5w6fw6q 3416 23 72.4 72.4 CD cord-006870-f5w6fw6q 3416 24 % % NN cord-006870-f5w6fw6q 3416 25 with with IN cord-006870-f5w6fw6q 3416 26 a a DT cord-006870-f5w6fw6q 3416 27 median median NN cord-006870-f5w6fw6q 3416 28 of of IN cord-006870-f5w6fw6q 3416 29 72.9 72.9 CD cord-006870-f5w6fw6q 3416 30 % % NN cord-006870-f5w6fw6q 3416 31 ( ( -LRB- cord-006870-f5w6fw6q 3416 32 range range NN cord-006870-f5w6fw6q 3416 33 61.4%-72.9 61.4%-72.9 NNP cord-006870-f5w6fw6q 3416 34 % % NN cord-006870-f5w6fw6q 3416 35 ) ) -RRB- cord-006870-f5w6fw6q 3416 36 . . . cord-006870-f5w6fw6q 3417 1 The the DT cord-006870-f5w6fw6q 3417 2 mean mean JJ cord-006870-f5w6fw6q 3417 3 post post JJ cord-006870-f5w6fw6q 3417 4 - - JJ cord-006870-f5w6fw6q 3417 5 test test JJ cord-006870-f5w6fw6q 3417 6 score score NN cord-006870-f5w6fw6q 3417 7 was be VBD cord-006870-f5w6fw6q 3417 8 86.7 86.7 CD cord-006870-f5w6fw6q 3417 9 % % NN cord-006870-f5w6fw6q 3417 10 with with IN cord-006870-f5w6fw6q 3417 11 a a DT cord-006870-f5w6fw6q 3417 12 median median NN cord-006870-f5w6fw6q 3417 13 of of IN cord-006870-f5w6fw6q 3417 14 88.6 88.6 CD cord-006870-f5w6fw6q 3417 15 % % NN cord-006870-f5w6fw6q 3417 16 ( ( -LRB- cord-006870-f5w6fw6q 3417 17 range range NN cord-006870-f5w6fw6q 3417 18 77.1%-94.3 77.1%-94.3 CD cord-006870-f5w6fw6q 3417 19 % % NN cord-006870-f5w6fw6q 3417 20 ) ) -RRB- cord-006870-f5w6fw6q 3417 21 . . . cord-006870-f5w6fw6q 3418 1 The the DT cord-006870-f5w6fw6q 3418 2 improvement improvement NN cord-006870-f5w6fw6q 3418 3 of of IN cord-006870-f5w6fw6q 3418 4 scores score NNS cord-006870-f5w6fw6q 3418 5 was be VBD cord-006870-f5w6fw6q 3418 6 statistically statistically RB cord-006870-f5w6fw6q 3418 7 significant significant JJ cord-006870-f5w6fw6q 3418 8 on on IN cord-006870-f5w6fw6q 3418 9 the the DT cord-006870-f5w6fw6q 3418 10 post post JJ cord-006870-f5w6fw6q 3418 11 - - JJ cord-006870-f5w6fw6q 3418 12 test test NN cord-006870-f5w6fw6q 3418 13 compared compare VBN cord-006870-f5w6fw6q 3418 14 to to IN cord-006870-f5w6fw6q 3418 15 the the DT cord-006870-f5w6fw6q 3418 16 pre pre JJ cord-006870-f5w6fw6q 3418 17 - - JJ cord-006870-f5w6fw6q 3418 18 test test JJ cord-006870-f5w6fw6q 3418 19 ( ( -LRB- cord-006870-f5w6fw6q 3418 20 86.7 86.7 CD cord-006870-f5w6fw6q 3418 21 % % NN cord-006870-f5w6fw6q 3418 22 vs. vs. CC cord-006870-f5w6fw6q 3418 23 72.4 72.4 CD cord-006870-f5w6fw6q 3418 24 % % NN cord-006870-f5w6fw6q 3418 25 % % NN cord-006870-f5w6fw6q 3418 26 , , , cord-006870-f5w6fw6q 3418 27 p p NN cord-006870-f5w6fw6q 3418 28 < < XX cord-006870-f5w6fw6q 3418 29 0.005 0.005 CD cord-006870-f5w6fw6q 3418 30 ) ) -RRB- cord-006870-f5w6fw6q 3418 31 . . . cord-006870-f5w6fw6q 3419 1 All all DT cord-006870-f5w6fw6q 3419 2 participants participant NNS cord-006870-f5w6fw6q 3419 3 in in IN cord-006870-f5w6fw6q 3419 4 the the DT cord-006870-f5w6fw6q 3419 5 Emergency Emergency NNP cord-006870-f5w6fw6q 3419 6 Neurological Neurological NNP cord-006870-f5w6fw6q 3419 7 Life Life NNP cord-006870-f5w6fw6q 3419 8 Support Support NNP cord-006870-f5w6fw6q 3419 9 course course NN cord-006870-f5w6fw6q 3419 10 showed show VBD cord-006870-f5w6fw6q 3419 11 improved improved JJ cord-006870-f5w6fw6q 3419 12 test test NN cord-006870-f5w6fw6q 3419 13 scores score NNS cord-006870-f5w6fw6q 3419 14 immediately immediately RB cord-006870-f5w6fw6q 3419 15 after after IN cord-006870-f5w6fw6q 3419 16 participation participation NN cord-006870-f5w6fw6q 3419 17 in in IN cord-006870-f5w6fw6q 3419 18 the the DT cord-006870-f5w6fw6q 3419 19 standard standard JJ cord-006870-f5w6fw6q 3419 20 ENLS enl NNS cord-006870-f5w6fw6q 3419 21 course course NN cord-006870-f5w6fw6q 3419 22 . . . cord-006870-f5w6fw6q 3420 1 This this DT cord-006870-f5w6fw6q 3420 2 study study NN cord-006870-f5w6fw6q 3420 3 will will MD cord-006870-f5w6fw6q 3420 4 assess assess VB cord-006870-f5w6fw6q 3420 5 knowledge knowledge NN cord-006870-f5w6fw6q 3420 6 retention retention NN cord-006870-f5w6fw6q 3420 7 at at IN cord-006870-f5w6fw6q 3420 8 6-months 6-months CD cord-006870-f5w6fw6q 3420 9 following follow VBG cord-006870-f5w6fw6q 3420 10 training training NN cord-006870-f5w6fw6q 3420 11 , , , cord-006870-f5w6fw6q 3420 12 and and CC cord-006870-f5w6fw6q 3420 13 is be VBZ cord-006870-f5w6fw6q 3420 14 actively actively RB cord-006870-f5w6fw6q 3420 15 enrolling enrol VBG cord-006870-f5w6fw6q 3420 16 new new JJ cord-006870-f5w6fw6q 3420 17 participants participant NNS cord-006870-f5w6fw6q 3420 18 . . . cord-006870-f5w6fw6q 3421 1 Augmented augment VBN cord-006870-f5w6fw6q 3421 2 renal renal JJ cord-006870-f5w6fw6q 3421 3 clearance clearance NN cord-006870-f5w6fw6q 3421 4 ( ( -LRB- cord-006870-f5w6fw6q 3421 5 ARC ARC NNP cord-006870-f5w6fw6q 3421 6 , , , cord-006870-f5w6fw6q 3421 7 defined define VBN cord-006870-f5w6fw6q 3421 8 as as IN cord-006870-f5w6fw6q 3421 9 a a DT cord-006870-f5w6fw6q 3421 10 creatinine creatinine NN cord-006870-f5w6fw6q 3421 11 clearance clearance NN cord-006870-f5w6fw6q 3421 12 of of IN cord-006870-f5w6fw6q 3421 13 > > XX cord-006870-f5w6fw6q 3421 14 150ml 150ml NNP cord-006870-f5w6fw6q 3421 15 / / SYM cord-006870-f5w6fw6q 3421 16 min min NN cord-006870-f5w6fw6q 3421 17 ) ) -RRB- cord-006870-f5w6fw6q 3421 18 has have VBZ cord-006870-f5w6fw6q 3421 19 been be VBN cord-006870-f5w6fw6q 3421 20 demonstrated demonstrate VBN cord-006870-f5w6fw6q 3421 21 in in IN cord-006870-f5w6fw6q 3421 22 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3421 23 care care NN cord-006870-f5w6fw6q 3421 24 disease disease NN cord-006870-f5w6fw6q 3421 25 states state NNS cord-006870-f5w6fw6q 3421 26 such such JJ cord-006870-f5w6fw6q 3421 27 as as IN cord-006870-f5w6fw6q 3421 28 traumatic traumatic JJ cord-006870-f5w6fw6q 3421 29 brain brain NN cord-006870-f5w6fw6q 3421 30 injury injury NN cord-006870-f5w6fw6q 3421 31 , , , cord-006870-f5w6fw6q 3421 32 intracranial intracranial JJ cord-006870-f5w6fw6q 3421 33 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3421 34 , , , cord-006870-f5w6fw6q 3421 35 and and CC cord-006870-f5w6fw6q 3421 36 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3421 37 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3421 38 . . . cord-006870-f5w6fw6q 3422 1 ARC ARC NNP cord-006870-f5w6fw6q 3422 2 may may MD cord-006870-f5w6fw6q 3422 3 result result VB cord-006870-f5w6fw6q 3422 4 in in IN cord-006870-f5w6fw6q 3422 5 increased increase VBN cord-006870-f5w6fw6q 3422 6 elimination elimination NN cord-006870-f5w6fw6q 3422 7 of of IN cord-006870-f5w6fw6q 3422 8 renallyeliminated renallyeliminated JJ cord-006870-f5w6fw6q 3422 9 medications medication NNS cord-006870-f5w6fw6q 3422 10 , , , cord-006870-f5w6fw6q 3422 11 thereby thereby RB cord-006870-f5w6fw6q 3422 12 reducing reduce VBG cord-006870-f5w6fw6q 3422 13 drug drug NN cord-006870-f5w6fw6q 3422 14 exposure exposure NN cord-006870-f5w6fw6q 3422 15 with with IN cord-006870-f5w6fw6q 3422 16 standard standard JJ cord-006870-f5w6fw6q 3422 17 doses dose NNS cord-006870-f5w6fw6q 3422 18 . . . cord-006870-f5w6fw6q 3423 1 The the DT cord-006870-f5w6fw6q 3423 2 overall overall JJ cord-006870-f5w6fw6q 3423 3 prevalence prevalence NN cord-006870-f5w6fw6q 3423 4 of of IN cord-006870-f5w6fw6q 3423 5 ARC ARC NNP cord-006870-f5w6fw6q 3423 6 is be VBZ cord-006870-f5w6fw6q 3423 7 not not RB cord-006870-f5w6fw6q 3423 8 well well RB cord-006870-f5w6fw6q 3423 9 described describe VBN cord-006870-f5w6fw6q 3423 10 . . . cord-006870-f5w6fw6q 3424 1 The the DT cord-006870-f5w6fw6q 3424 2 purpose purpose NN cord-006870-f5w6fw6q 3424 3 of of IN cord-006870-f5w6fw6q 3424 4 this this DT cord-006870-f5w6fw6q 3424 5 study study NN cord-006870-f5w6fw6q 3424 6 was be VBD cord-006870-f5w6fw6q 3424 7 to to TO cord-006870-f5w6fw6q 3424 8 estimate estimate VB cord-006870-f5w6fw6q 3424 9 the the DT cord-006870-f5w6fw6q 3424 10 overall overall JJ cord-006870-f5w6fw6q 3424 11 prevalence prevalence NN cord-006870-f5w6fw6q 3424 12 of of IN cord-006870-f5w6fw6q 3424 13 ARC ARC NNP cord-006870-f5w6fw6q 3424 14 in in IN cord-006870-f5w6fw6q 3424 15 a a DT cord-006870-f5w6fw6q 3424 16 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3424 17 care care NN cord-006870-f5w6fw6q 3424 18 population population NN cord-006870-f5w6fw6q 3424 19 . . . cord-006870-f5w6fw6q 3425 1 This this DT cord-006870-f5w6fw6q 3425 2 was be VBD cord-006870-f5w6fw6q 3425 3 a a DT cord-006870-f5w6fw6q 3425 4 retrospective retrospective JJ cord-006870-f5w6fw6q 3425 5 cohort cohort NN cord-006870-f5w6fw6q 3425 6 study study NN cord-006870-f5w6fw6q 3425 7 of of IN cord-006870-f5w6fw6q 3425 8 adults adult NNS cord-006870-f5w6fw6q 3425 9 > > XX cord-006870-f5w6fw6q 3426 1 18 18 CD cord-006870-f5w6fw6q 3426 2 years year NNS cord-006870-f5w6fw6q 3426 3 of of IN cord-006870-f5w6fw6q 3426 4 age age NN cord-006870-f5w6fw6q 3426 5 admitted admit VBD cord-006870-f5w6fw6q 3426 6 to to IN cord-006870-f5w6fw6q 3426 7 the the DT cord-006870-f5w6fw6q 3426 8 intensive intensive JJ cord-006870-f5w6fw6q 3426 9 care care NN cord-006870-f5w6fw6q 3426 10 unit unit NN cord-006870-f5w6fw6q 3426 11 on on IN cord-006870-f5w6fw6q 3426 12 the the DT cord-006870-f5w6fw6q 3426 13 neurosurgery neurosurgery NNP cord-006870-f5w6fw6q 3426 14 service service NN cord-006870-f5w6fw6q 3426 15 . . . cord-006870-f5w6fw6q 3427 1 Demographic demographic JJ cord-006870-f5w6fw6q 3427 2 and and CC cord-006870-f5w6fw6q 3427 3 pertinent pertinent JJ cord-006870-f5w6fw6q 3427 4 laboratory laboratory NN cord-006870-f5w6fw6q 3427 5 data datum NNS cord-006870-f5w6fw6q 3427 6 were be VBD cord-006870-f5w6fw6q 3427 7 collected collect VBN cord-006870-f5w6fw6q 3427 8 for for IN cord-006870-f5w6fw6q 3427 9 patients patient NNS cord-006870-f5w6fw6q 3427 10 admitted admit VBN cord-006870-f5w6fw6q 3427 11 from from IN cord-006870-f5w6fw6q 3427 12 January January NNP cord-006870-f5w6fw6q 3427 13 1 1 CD cord-006870-f5w6fw6q 3427 14 , , , cord-006870-f5w6fw6q 3427 15 2016 2016 CD cord-006870-f5w6fw6q 3427 16 thru thru IN cord-006870-f5w6fw6q 3427 17 December December NNP cord-006870-f5w6fw6q 3427 18 31 31 CD cord-006870-f5w6fw6q 3427 19 , , , cord-006870-f5w6fw6q 3427 20 2016 2016 CD cord-006870-f5w6fw6q 3427 21 . . . cord-006870-f5w6fw6q 3428 1 An an DT cord-006870-f5w6fw6q 3428 2 ARCTIC ARCTIC NNP cord-006870-f5w6fw6q 3428 3 score score NN cord-006870-f5w6fw6q 3428 4 was be VBD cord-006870-f5w6fw6q 3428 5 calculated calculate VBN cord-006870-f5w6fw6q 3428 6 for for IN cord-006870-f5w6fw6q 3428 7 each each DT cord-006870-f5w6fw6q 3428 8 patient patient NN cord-006870-f5w6fw6q 3428 9 ( ( -LRB- cord-006870-f5w6fw6q 3428 10 6 6 CD cord-006870-f5w6fw6q 3428 11 or or CC cord-006870-f5w6fw6q 3428 12 greater great JJR cord-006870-f5w6fw6q 3428 13 suggests suggest VBZ cord-006870-f5w6fw6q 3428 14 ARC ARC NNP cord-006870-f5w6fw6q 3428 15 ) ) -RRB- cord-006870-f5w6fw6q 3428 16 . . . cord-006870-f5w6fw6q 3429 1 Parametric Parametric NNP cord-006870-f5w6fw6q 3429 2 data datum NNS cord-006870-f5w6fw6q 3429 3 was be VBD cord-006870-f5w6fw6q 3429 4 compared compare VBN cord-006870-f5w6fw6q 3429 5 using use VBG cord-006870-f5w6fw6q 3429 6 one one CD cord-006870-f5w6fw6q 3429 7 - - HYPH cord-006870-f5w6fw6q 3429 8 sample sample NN cord-006870-f5w6fw6q 3429 9 Student Student NNP cord-006870-f5w6fw6q 3429 10 's 's POS cord-006870-f5w6fw6q 3429 11 T t NN cord-006870-f5w6fw6q 3429 12 - - HYPH cord-006870-f5w6fw6q 3429 13 test test NN cord-006870-f5w6fw6q 3429 14 , , , cord-006870-f5w6fw6q 3429 15 nominal nominal JJ cord-006870-f5w6fw6q 3429 16 data datum NNS cord-006870-f5w6fw6q 3429 17 was be VBD cord-006870-f5w6fw6q 3429 18 compared compare VBN cord-006870-f5w6fw6q 3429 19 using use VBG cord-006870-f5w6fw6q 3429 20 Fisher Fisher NNP cord-006870-f5w6fw6q 3429 21 's 's POS cord-006870-f5w6fw6q 3429 22 exact exact JJ cord-006870-f5w6fw6q 3429 23 test test NN cord-006870-f5w6fw6q 3429 24 ( ( -LRB- cord-006870-f5w6fw6q 3429 25 alpha alpha NN cord-006870-f5w6fw6q 3429 26 = = SYM cord-006870-f5w6fw6q 3429 27 0.05 0.05 CD cord-006870-f5w6fw6q 3429 28 ) ) -RRB- cord-006870-f5w6fw6q 3429 29 . . . cord-006870-f5w6fw6q 3430 1 Statistical statistical JJ cord-006870-f5w6fw6q 3430 2 analysis analysis NN cord-006870-f5w6fw6q 3430 3 was be VBD cord-006870-f5w6fw6q 3430 4 conducted conduct VBN cord-006870-f5w6fw6q 3430 5 using use VBG cord-006870-f5w6fw6q 3430 6 IBM IBM NNP cord-006870-f5w6fw6q 3430 7 SPSS SPSS NNP cord-006870-f5w6fw6q 3430 8 version version NN cord-006870-f5w6fw6q 3430 9 24 24 CD cord-006870-f5w6fw6q 3430 10 . . . cord-006870-f5w6fw6q 3431 1 present present JJ cord-006870-f5w6fw6q 3431 2 in in IN cord-006870-f5w6fw6q 3431 3 a a DT cord-006870-f5w6fw6q 3431 4 total total NN cord-006870-f5w6fw6q 3431 5 of of IN cord-006870-f5w6fw6q 3431 6 37.24 37.24 CD cord-006870-f5w6fw6q 3431 7 % % NN cord-006870-f5w6fw6q 3431 8 of of IN cord-006870-f5w6fw6q 3431 9 patients patient NNS cord-006870-f5w6fw6q 3431 10 . . . cord-006870-f5w6fw6q 3432 1 A a DT cord-006870-f5w6fw6q 3432 2 broad broad JJ cord-006870-f5w6fw6q 3432 3 spectrum spectrum NN cord-006870-f5w6fw6q 3432 4 of of IN cord-006870-f5w6fw6q 3432 5 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3432 6 care care NN cord-006870-f5w6fw6q 3432 7 diagnoses diagnosis NNS cord-006870-f5w6fw6q 3432 8 was be VBD cord-006870-f5w6fw6q 3432 9 present present JJ cord-006870-f5w6fw6q 3432 10 . . . cord-006870-f5w6fw6q 3433 1 The the DT cord-006870-f5w6fw6q 3433 2 mean mean JJ cord-006870-f5w6fw6q 3433 3 age age NN cord-006870-f5w6fw6q 3433 4 in in IN cord-006870-f5w6fw6q 3433 5 years year NNS cord-006870-f5w6fw6q 3433 6 was be VBD cord-006870-f5w6fw6q 3433 7 significantly significantly RB cord-006870-f5w6fw6q 3433 8 lower low JJR cord-006870-f5w6fw6q 3433 9 in in IN cord-006870-f5w6fw6q 3433 10 patients patient NNS cord-006870-f5w6fw6q 3433 11 with with IN cord-006870-f5w6fw6q 3433 12 ARC ARC NNP cord-006870-f5w6fw6q 3433 13 [ [ -LRB- cord-006870-f5w6fw6q 3433 14 47.8 47.8 CD cord-006870-f5w6fw6q 3433 15 ( ( -LRB- cord-006870-f5w6fw6q 3433 16 14SD 14sd CD cord-006870-f5w6fw6q 3433 17 ) ) -RRB- cord-006870-f5w6fw6q 3433 18 ] ] -RRB- cord-006870-f5w6fw6q 3433 19 than than IN cord-006870-f5w6fw6q 3433 20 without without IN cord-006870-f5w6fw6q 3433 21 ARC ARC NNP cord-006870-f5w6fw6q 3433 22 [ [ -LRB- cord-006870-f5w6fw6q 3433 23 54 54 CD cord-006870-f5w6fw6q 3433 24 ( ( -LRB- cord-006870-f5w6fw6q 3433 25 17SD 17sd CD cord-006870-f5w6fw6q 3433 26 ) ) -RRB- cord-006870-f5w6fw6q 3433 27 , , . cord-006870-f5w6fw6q 3434 1 p p NN cord-006870-f5w6fw6q 3434 2 = = SYM cord-006870-f5w6fw6q 3434 3 0.026 0.026 CD cord-006870-f5w6fw6q 3434 4 ] ] -RRB- cord-006870-f5w6fw6q 3434 5 , , , cord-006870-f5w6fw6q 3434 6 as as IN cord-006870-f5w6fw6q 3434 7 was be VBD cord-006870-f5w6fw6q 3434 8 the the DT cord-006870-f5w6fw6q 3434 9 serum serum NN cord-006870-f5w6fw6q 3434 10 creatinine creatinine NN cord-006870-f5w6fw6q 3434 11 [ [ -LRB- cord-006870-f5w6fw6q 3434 12 with with IN cord-006870-f5w6fw6q 3434 13 ARC ARC NNP cord-006870-f5w6fw6q 3434 14 0.55mg 0.55mg CD cord-006870-f5w6fw6q 3434 15 / / SYM cord-006870-f5w6fw6q 3434 16 dl dl NN cord-006870-f5w6fw6q 3434 17 ( ( -LRB- cord-006870-f5w6fw6q 3434 18 0.1SD 0.1sd CD cord-006870-f5w6fw6q 3434 19 ) ) -RRB- cord-006870-f5w6fw6q 3434 20 vs vs IN cord-006870-f5w6fw6q 3434 21 without without IN cord-006870-f5w6fw6q 3434 22 ARC ARC NNP cord-006870-f5w6fw6q 3434 23 1mg 1mg NNP cord-006870-f5w6fw6q 3434 24 / / SYM cord-006870-f5w6fw6q 3434 25 dl dl NNP cord-006870-f5w6fw6q 3434 26 ( ( -LRB- cord-006870-f5w6fw6q 3434 27 0.6SD 0.6sd CD cord-006870-f5w6fw6q 3434 28 ) ) -RRB- cord-006870-f5w6fw6q 3434 29 , , , cord-006870-f5w6fw6q 3434 30 p p NN cord-006870-f5w6fw6q 3434 31 < < XX cord-006870-f5w6fw6q 3434 32 0.001 0.001 CD cord-006870-f5w6fw6q 3434 33 ] ] -RRB- cord-006870-f5w6fw6q 3434 34 . . . cord-006870-f5w6fw6q 3435 1 Mean mean JJ cord-006870-f5w6fw6q 3435 2 hospital hospital NN cord-006870-f5w6fw6q 3435 3 length length NN cord-006870-f5w6fw6q 3435 4 of of IN cord-006870-f5w6fw6q 3435 5 stay stay NN cord-006870-f5w6fw6q 3435 6 was be VBD cord-006870-f5w6fw6q 3435 7 greater great JJR cord-006870-f5w6fw6q 3435 8 in in IN cord-006870-f5w6fw6q 3435 9 patients patient NNS cord-006870-f5w6fw6q 3435 10 with with IN cord-006870-f5w6fw6q 3435 11 ARC ARC NNP cord-006870-f5w6fw6q 3435 12 than than IN cord-006870-f5w6fw6q 3435 13 without without IN cord-006870-f5w6fw6q 3435 14 [ [ -LRB- cord-006870-f5w6fw6q 3435 15 10.1 10.1 CD cord-006870-f5w6fw6q 3435 16 ( ( -LRB- cord-006870-f5w6fw6q 3435 17 10SD 10sd CD cord-006870-f5w6fw6q 3435 18 ) ) -RRB- cord-006870-f5w6fw6q 3435 19 vs vs IN cord-006870-f5w6fw6q 3435 20 6.5 6.5 CD cord-006870-f5w6fw6q 3435 21 ( ( -LRB- cord-006870-f5w6fw6q 3435 22 10SD 10sd CD cord-006870-f5w6fw6q 3435 23 ) ) -RRB- cord-006870-f5w6fw6q 3435 24 , , , cord-006870-f5w6fw6q 3435 25 p p NN cord-006870-f5w6fw6q 3435 26 < < XX cord-006870-f5w6fw6q 3435 27 0.001 0.001 CD cord-006870-f5w6fw6q 3435 28 ] ] -RRB- cord-006870-f5w6fw6q 3435 29 . . . cord-006870-f5w6fw6q 3436 1 ARC ARC NNP cord-006870-f5w6fw6q 3436 2 occurs occur VBZ cord-006870-f5w6fw6q 3436 3 commonly commonly RB cord-006870-f5w6fw6q 3436 4 in in IN cord-006870-f5w6fw6q 3436 5 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3436 6 care care NN cord-006870-f5w6fw6q 3436 7 patients patient NNS cord-006870-f5w6fw6q 3436 8 and and CC cord-006870-f5w6fw6q 3436 9 likely likely JJ cord-006870-f5w6fw6q 3436 10 merits merit NNS cord-006870-f5w6fw6q 3436 11 proactive proactive JJ cord-006870-f5w6fw6q 3436 12 screening screening NN cord-006870-f5w6fw6q 3436 13 or or CC cord-006870-f5w6fw6q 3436 14 direct direct JJ cord-006870-f5w6fw6q 3436 15 measurement measurement NN cord-006870-f5w6fw6q 3436 16 of of IN cord-006870-f5w6fw6q 3436 17 creatinine creatinine NN cord-006870-f5w6fw6q 3436 18 clearance clearance NN cord-006870-f5w6fw6q 3436 19 in in IN cord-006870-f5w6fw6q 3436 20 select select JJ cord-006870-f5w6fw6q 3436 21 patients patient NNS cord-006870-f5w6fw6q 3436 22 . . . cord-006870-f5w6fw6q 3437 1 Pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 3437 2 studies study NNS cord-006870-f5w6fw6q 3437 3 of of IN cord-006870-f5w6fw6q 3437 4 commonly commonly RB cord-006870-f5w6fw6q 3437 5 used use VBN cord-006870-f5w6fw6q 3437 6 renally renally NN cord-006870-f5w6fw6q 3437 7 - - HYPH cord-006870-f5w6fw6q 3437 8 eliminated eliminate VBN cord-006870-f5w6fw6q 3437 9 medications medication NNS cord-006870-f5w6fw6q 3437 10 may may MD cord-006870-f5w6fw6q 3437 11 be be VB cord-006870-f5w6fw6q 3437 12 needed need VBN cord-006870-f5w6fw6q 3437 13 to to TO cord-006870-f5w6fw6q 3437 14 establish establish VB cord-006870-f5w6fw6q 3437 15 population population NN cord-006870-f5w6fw6q 3437 16 parameters parameter NNS cord-006870-f5w6fw6q 3437 17 in in IN cord-006870-f5w6fw6q 3437 18 the the DT cord-006870-f5w6fw6q 3437 19 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3437 20 care care NN cord-006870-f5w6fw6q 3437 21 population population NN cord-006870-f5w6fw6q 3437 22 . . . cord-006870-f5w6fw6q 3438 1 Education education NN cord-006870-f5w6fw6q 3438 2 surveys survey NNS cord-006870-f5w6fw6q 3438 3 demonstrate demonstrate VBP cord-006870-f5w6fw6q 3438 4 gaps gap NNS cord-006870-f5w6fw6q 3438 5 in in IN cord-006870-f5w6fw6q 3438 6 resident resident JJ cord-006870-f5w6fw6q 3438 7 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3438 8 care care NN cord-006870-f5w6fw6q 3438 9 education education NN cord-006870-f5w6fw6q 3438 10 and and CC cord-006870-f5w6fw6q 3438 11 training training NN cord-006870-f5w6fw6q 3438 12 . . . cord-006870-f5w6fw6q 3439 1 We -PRON- PRP cord-006870-f5w6fw6q 3439 2 assessed assess VBD cord-006870-f5w6fw6q 3439 3 junior junior JJ cord-006870-f5w6fw6q 3439 4 residents resident NNS cord-006870-f5w6fw6q 3439 5 ' ' POS cord-006870-f5w6fw6q 3439 6 baseline baseline JJ cord-006870-f5w6fw6q 3439 7 knowledge knowledge NN cord-006870-f5w6fw6q 3439 8 of of IN cord-006870-f5w6fw6q 3439 9 neurologic neurologic JJ cord-006870-f5w6fw6q 3439 10 emergencies emergency NNS cord-006870-f5w6fw6q 3439 11 , , , cord-006870-f5w6fw6q 3439 12 procedural procedural JJ cord-006870-f5w6fw6q 3439 13 competency competency NN cord-006870-f5w6fw6q 3439 14 , , , cord-006870-f5w6fw6q 3439 15 knowledge knowledge NN cord-006870-f5w6fw6q 3439 16 of of IN cord-006870-f5w6fw6q 3439 17 available available JJ cord-006870-f5w6fw6q 3439 18 resources resource NNS cord-006870-f5w6fw6q 3439 19 , , , cord-006870-f5w6fw6q 3439 20 and and CC cord-006870-f5w6fw6q 3439 21 the the DT cord-006870-f5w6fw6q 3439 22 impact impact NN cord-006870-f5w6fw6q 3439 23 of of IN cord-006870-f5w6fw6q 3439 24 pre pre JJ cord-006870-f5w6fw6q 3439 25 - - JJ cord-006870-f5w6fw6q 3439 26 rotation rotation JJ cord-006870-f5w6fw6q 3439 27 orientations orientation NNS cord-006870-f5w6fw6q 3439 28 . . . cord-006870-f5w6fw6q 3440 1 Junior junior JJ cord-006870-f5w6fw6q 3440 2 residents resident NNS cord-006870-f5w6fw6q 3440 3 ( ( -LRB- cord-006870-f5w6fw6q 3440 4 neurosurgery neurosurgery NNP cord-006870-f5w6fw6q 3440 5 PGY1s PGY1s NNP cord-006870-f5w6fw6q 3440 6 and and CC cord-006870-f5w6fw6q 3440 7 neurology neurology NNP cord-006870-f5w6fw6q 3440 8 PGY2s PGY2s NNP cord-006870-f5w6fw6q 3440 9 ) ) -RRB- cord-006870-f5w6fw6q 3440 10 who who WP cord-006870-f5w6fw6q 3440 11 had have VBD cord-006870-f5w6fw6q 3440 12 not not RB cord-006870-f5w6fw6q 3440 13 previously previously RB cord-006870-f5w6fw6q 3440 14 rotated rotate VBN cord-006870-f5w6fw6q 3440 15 in in IN cord-006870-f5w6fw6q 3440 16 the the DT cord-006870-f5w6fw6q 3440 17 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 3440 18 were be VBD cord-006870-f5w6fw6q 3440 19 surveyed survey VBN cord-006870-f5w6fw6q 3440 20 . . . cord-006870-f5w6fw6q 3441 1 A a DT cord-006870-f5w6fw6q 3441 2 three three CD cord-006870-f5w6fw6q 3441 3 - - HYPH cord-006870-f5w6fw6q 3441 4 part part NN cord-006870-f5w6fw6q 3441 5 survey survey NN cord-006870-f5w6fw6q 3441 6 was be VBD cord-006870-f5w6fw6q 3441 7 administered administer VBN cord-006870-f5w6fw6q 3441 8 : : : cord-006870-f5w6fw6q 3441 9 Part part NN cord-006870-f5w6fw6q 3441 10 I -PRON- PRP cord-006870-f5w6fw6q 3441 11 , , , cord-006870-f5w6fw6q 3441 12 knowledge knowledge NN cord-006870-f5w6fw6q 3441 13 of of IN cord-006870-f5w6fw6q 3441 14 ICU ICU NNP cord-006870-f5w6fw6q 3441 15 structure structure NN cord-006870-f5w6fw6q 3441 16 and and CC cord-006870-f5w6fw6q 3441 17 personnel personnel NNS cord-006870-f5w6fw6q 3441 18 ; ; : cord-006870-f5w6fw6q 3441 19 Part Part NNP cord-006870-f5w6fw6q 3441 20 II II NNP cord-006870-f5w6fw6q 3441 21 , , , cord-006870-f5w6fw6q 3441 22 procedural procedural JJ cord-006870-f5w6fw6q 3441 23 competency competency NN cord-006870-f5w6fw6q 3441 24 ; ; : cord-006870-f5w6fw6q 3441 25 Part Part NNP cord-006870-f5w6fw6q 3441 26 III III NNP cord-006870-f5w6fw6q 3441 27 , , , cord-006870-f5w6fw6q 3441 28 comfort comfort NN cord-006870-f5w6fw6q 3441 29 with with IN cord-006870-f5w6fw6q 3441 30 common common JJ cord-006870-f5w6fw6q 3441 31 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3441 32 care care NN cord-006870-f5w6fw6q 3441 33 emergencies emergency NNS cord-006870-f5w6fw6q 3441 34 . . . cord-006870-f5w6fw6q 3442 1 The the DT cord-006870-f5w6fw6q 3442 2 survey survey NN cord-006870-f5w6fw6q 3442 3 was be VBD cord-006870-f5w6fw6q 3442 4 comprised comprise VBN cord-006870-f5w6fw6q 3442 5 of of IN cord-006870-f5w6fw6q 3442 6 selection selection NN cord-006870-f5w6fw6q 3442 7 responses response NNS cord-006870-f5w6fw6q 3442 8 . . . cord-006870-f5w6fw6q 3443 1 After after IN cord-006870-f5w6fw6q 3443 2 the the DT cord-006870-f5w6fw6q 3443 3 survey survey NN cord-006870-f5w6fw6q 3443 4 but but CC cord-006870-f5w6fw6q 3443 5 prior prior RB cord-006870-f5w6fw6q 3443 6 to to IN cord-006870-f5w6fw6q 3443 7 starting start VBG cord-006870-f5w6fw6q 3443 8 the the DT cord-006870-f5w6fw6q 3443 9 rotation rotation NN cord-006870-f5w6fw6q 3443 10 , , , cord-006870-f5w6fw6q 3443 11 each each DT cord-006870-f5w6fw6q 3443 12 resident resident NN cord-006870-f5w6fw6q 3443 13 was be VBD cord-006870-f5w6fw6q 3443 14 oriented orient VBN cord-006870-f5w6fw6q 3443 15 to to IN cord-006870-f5w6fw6q 3443 16 the the DT cord-006870-f5w6fw6q 3443 17 unit unit NN cord-006870-f5w6fw6q 3443 18 by by IN cord-006870-f5w6fw6q 3443 19 a a DT cord-006870-f5w6fw6q 3443 20 neuroICU neuroicu NN cord-006870-f5w6fw6q 3443 21 attending attend VBG cord-006870-f5w6fw6q 3443 22 and and CC cord-006870-f5w6fw6q 3443 23 nursing nursing NN cord-006870-f5w6fw6q 3443 24 director director NN cord-006870-f5w6fw6q 3443 25 . . . cord-006870-f5w6fw6q 3444 1 This this DT cord-006870-f5w6fw6q 3444 2 orientation orientation NN cord-006870-f5w6fw6q 3444 3 reviewed review VBD cord-006870-f5w6fw6q 3444 4 rotation rotation NN cord-006870-f5w6fw6q 3444 5 goals goal NNS cord-006870-f5w6fw6q 3444 6 , , , cord-006870-f5w6fw6q 3444 7 ICU ICU NNP cord-006870-f5w6fw6q 3444 8 structure structure NN cord-006870-f5w6fw6q 3444 9 , , , cord-006870-f5w6fw6q 3444 10 personnel personnel NNS cord-006870-f5w6fw6q 3444 11 and and CC cord-006870-f5w6fw6q 3444 12 rounding round VBG cord-006870-f5w6fw6q 3444 13 expectations expectation NNS cord-006870-f5w6fw6q 3444 14 . . . cord-006870-f5w6fw6q 3445 1 A a DT cord-006870-f5w6fw6q 3445 2 survey survey NN cord-006870-f5w6fw6q 3445 3 was be VBD cord-006870-f5w6fw6q 3445 4 repeated repeat VBN cord-006870-f5w6fw6q 3445 5 to to TO cord-006870-f5w6fw6q 3445 6 evaluate evaluate VB cord-006870-f5w6fw6q 3445 7 the the DT cord-006870-f5w6fw6q 3445 8 orientation orientation NN cord-006870-f5w6fw6q 3445 9 . . . cord-006870-f5w6fw6q 3446 1 Of of IN cord-006870-f5w6fw6q 3446 2 15 15 CD cord-006870-f5w6fw6q 3446 3 residents resident NNS cord-006870-f5w6fw6q 3446 4 who who WP cord-006870-f5w6fw6q 3446 5 had have VBD cord-006870-f5w6fw6q 3446 6 not not RB cord-006870-f5w6fw6q 3446 7 rotated rotate VBN cord-006870-f5w6fw6q 3446 8 in in IN cord-006870-f5w6fw6q 3446 9 the the DT cord-006870-f5w6fw6q 3446 10 ICU ICU NNP cord-006870-f5w6fw6q 3446 11 , , , cord-006870-f5w6fw6q 3446 12 10 10 CD cord-006870-f5w6fw6q 3446 13 ( ( -LRB- cord-006870-f5w6fw6q 3446 14 66.7 66.7 CD cord-006870-f5w6fw6q 3446 15 % % NN cord-006870-f5w6fw6q 3446 16 ) ) -RRB- cord-006870-f5w6fw6q 3446 17 responded respond VBD cord-006870-f5w6fw6q 3446 18 . . . cord-006870-f5w6fw6q 3447 1 None none NN cord-006870-f5w6fw6q 3447 2 of of IN cord-006870-f5w6fw6q 3447 3 the the DT cord-006870-f5w6fw6q 3447 4 residents resident NNS cord-006870-f5w6fw6q 3447 5 understood understand VBD cord-006870-f5w6fw6q 3447 6 their -PRON- PRP$ cord-006870-f5w6fw6q 3447 7 specific specific JJ cord-006870-f5w6fw6q 3447 8 role role NN cord-006870-f5w6fw6q 3447 9 within within IN cord-006870-f5w6fw6q 3447 10 the the DT cord-006870-f5w6fw6q 3447 11 ICU ICU NNP cord-006870-f5w6fw6q 3447 12 team team NN cord-006870-f5w6fw6q 3447 13 . . . cord-006870-f5w6fw6q 3448 1 80 80 CD cord-006870-f5w6fw6q 3448 2 % % NN cord-006870-f5w6fw6q 3448 3 did do VBD cord-006870-f5w6fw6q 3448 4 not not RB cord-006870-f5w6fw6q 3448 5 understand understand VB cord-006870-f5w6fw6q 3448 6 the the DT cord-006870-f5w6fw6q 3448 7 role role NN cord-006870-f5w6fw6q 3448 8 of of IN cord-006870-f5w6fw6q 3448 9 the the DT cord-006870-f5w6fw6q 3448 10 resource resource NN cord-006870-f5w6fw6q 3448 11 nurse nurse NN cord-006870-f5w6fw6q 3448 12 and and CC cord-006870-f5w6fw6q 3448 13 were be VBD cord-006870-f5w6fw6q 3448 14 unaware unaware JJ cord-006870-f5w6fw6q 3448 15 of of IN cord-006870-f5w6fw6q 3448 16 where where WRB cord-006870-f5w6fw6q 3448 17 to to TO cord-006870-f5w6fw6q 3448 18 find find VB cord-006870-f5w6fw6q 3448 19 procedure procedure NN cord-006870-f5w6fw6q 3448 20 equipment equipment NN cord-006870-f5w6fw6q 3448 21 . . . cord-006870-f5w6fw6q 3449 1 60 60 CD cord-006870-f5w6fw6q 3449 2 % % NN cord-006870-f5w6fw6q 3449 3 of of IN cord-006870-f5w6fw6q 3449 4 residents resident NNS cord-006870-f5w6fw6q 3449 5 were be VBD cord-006870-f5w6fw6q 3449 6 not not RB cord-006870-f5w6fw6q 3449 7 comfortable comfortable JJ cord-006870-f5w6fw6q 3449 8 placing place VBG cord-006870-f5w6fw6q 3449 9 an an DT cord-006870-f5w6fw6q 3449 10 A a NN cord-006870-f5w6fw6q 3449 11 - - HYPH cord-006870-f5w6fw6q 3449 12 line line NN cord-006870-f5w6fw6q 3449 13 ; ; : cord-006870-f5w6fw6q 3449 14 30 30 CD cord-006870-f5w6fw6q 3449 15 % % NN cord-006870-f5w6fw6q 3449 16 were be VBD cord-006870-f5w6fw6q 3449 17 not not RB cord-006870-f5w6fw6q 3449 18 comfortable comfortable JJ cord-006870-f5w6fw6q 3449 19 performing perform VBG cord-006870-f5w6fw6q 3449 20 a a DT cord-006870-f5w6fw6q 3449 21 lumbar lumbar JJ cord-006870-f5w6fw6q 3449 22 puncture puncture NN cord-006870-f5w6fw6q 3449 23 . . . cord-006870-f5w6fw6q 3450 1 Over over IN cord-006870-f5w6fw6q 3450 2 half half NN cord-006870-f5w6fw6q 3450 3 of of IN cord-006870-f5w6fw6q 3450 4 respondents respondent NNS cord-006870-f5w6fw6q 3450 5 said say VBD cord-006870-f5w6fw6q 3450 6 they -PRON- PRP cord-006870-f5w6fw6q 3450 7 " " `` cord-006870-f5w6fw6q 3450 8 did do VBD cord-006870-f5w6fw6q 3450 9 n't not RB cord-006870-f5w6fw6q 3450 10 know know VB cord-006870-f5w6fw6q 3450 11 and and CC cord-006870-f5w6fw6q 3450 12 could could MD cord-006870-f5w6fw6q 3450 13 not not RB cord-006870-f5w6fw6q 3450 14 easily easily RB cord-006870-f5w6fw6q 3450 15 find find VB cord-006870-f5w6fw6q 3450 16 " " '' cord-006870-f5w6fw6q 3450 17 the the DT cord-006870-f5w6fw6q 3450 18 indications indication NNS cord-006870-f5w6fw6q 3450 19 for for IN cord-006870-f5w6fw6q 3450 20 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 3450 21 after after IN cord-006870-f5w6fw6q 3450 22 malignant malignant JJ cord-006870-f5w6fw6q 3450 23 MCA MCA NNP cord-006870-f5w6fw6q 3450 24 ischemia ischemia NN cord-006870-f5w6fw6q 3450 25 , , , cord-006870-f5w6fw6q 3450 26 the the DT cord-006870-f5w6fw6q 3450 27 indications indication NNS cord-006870-f5w6fw6q 3450 28 for for IN cord-006870-f5w6fw6q 3450 29 ICP ICP NNP cord-006870-f5w6fw6q 3450 30 monitoring monitoring NN cord-006870-f5w6fw6q 3450 31 , , , cord-006870-f5w6fw6q 3450 32 or or CC cord-006870-f5w6fw6q 3450 33 the the DT cord-006870-f5w6fw6q 3450 34 initial initial JJ cord-006870-f5w6fw6q 3450 35 workup workup NN cord-006870-f5w6fw6q 3450 36 of of IN cord-006870-f5w6fw6q 3450 37 autoimmune autoimmune JJ cord-006870-f5w6fw6q 3450 38 encephalitis encephalitis RB cord-006870-f5w6fw6q 3450 39 . . . cord-006870-f5w6fw6q 3451 1 14 14 CD cord-006870-f5w6fw6q 3451 2 residents resident NNS cord-006870-f5w6fw6q 3451 3 responded respond VBD cord-006870-f5w6fw6q 3451 4 to to TO cord-006870-f5w6fw6q 3451 5 post post VB cord-006870-f5w6fw6q 3451 6 orientation orientation NN cord-006870-f5w6fw6q 3451 7 surveys survey NNS cord-006870-f5w6fw6q 3451 8 . . . cord-006870-f5w6fw6q 3452 1 76 76 CD cord-006870-f5w6fw6q 3452 2 % % NN cord-006870-f5w6fw6q 3452 3 felt feel VBD cord-006870-f5w6fw6q 3452 4 the the DT cord-006870-f5w6fw6q 3452 5 orientation orientation NN cord-006870-f5w6fw6q 3452 6 was be VBD cord-006870-f5w6fw6q 3452 7 helpful helpful JJ cord-006870-f5w6fw6q 3452 8 in in IN cord-006870-f5w6fw6q 3452 9 explaining explain VBG cord-006870-f5w6fw6q 3452 10 the the DT cord-006870-f5w6fw6q 3452 11 roles role NNS cord-006870-f5w6fw6q 3452 12 of of IN cord-006870-f5w6fw6q 3452 13 team team NN cord-006870-f5w6fw6q 3452 14 members member NNS cord-006870-f5w6fw6q 3452 15 . . . cord-006870-f5w6fw6q 3453 1 61 61 CD cord-006870-f5w6fw6q 3453 2 % % NN cord-006870-f5w6fw6q 3453 3 felt feel VBD cord-006870-f5w6fw6q 3453 4 it -PRON- PRP cord-006870-f5w6fw6q 3453 5 was be VBD cord-006870-f5w6fw6q 3453 6 at at IN cord-006870-f5w6fw6q 3453 7 least least JJS cord-006870-f5w6fw6q 3453 8 " " `` cord-006870-f5w6fw6q 3453 9 somewhat somewhat RB cord-006870-f5w6fw6q 3453 10 helpful helpful JJ cord-006870-f5w6fw6q 3453 11 " " '' cord-006870-f5w6fw6q 3453 12 in in IN cord-006870-f5w6fw6q 3453 13 understanding understand VBG cord-006870-f5w6fw6q 3453 14 the the DT cord-006870-f5w6fw6q 3453 15 role role NN cord-006870-f5w6fw6q 3453 16 of of IN cord-006870-f5w6fw6q 3453 17 the the DT cord-006870-f5w6fw6q 3453 18 resource resource NN cord-006870-f5w6fw6q 3453 19 nurse nurse NN cord-006870-f5w6fw6q 3453 20 . . . cord-006870-f5w6fw6q 3454 1 46 46 CD cord-006870-f5w6fw6q 3454 2 % % NN cord-006870-f5w6fw6q 3454 3 felt feel VBD cord-006870-f5w6fw6q 3454 4 the the DT cord-006870-f5w6fw6q 3454 5 orientation orientation NN cord-006870-f5w6fw6q 3454 6 was be VBD cord-006870-f5w6fw6q 3454 7 " " `` cord-006870-f5w6fw6q 3454 8 helpful helpful JJ cord-006870-f5w6fw6q 3454 9 " " '' cord-006870-f5w6fw6q 3454 10 and and CC cord-006870-f5w6fw6q 3454 11 38 38 CD cord-006870-f5w6fw6q 3454 12 % % NN cord-006870-f5w6fw6q 3454 13 felt feel VBD cord-006870-f5w6fw6q 3454 14 it -PRON- PRP cord-006870-f5w6fw6q 3454 15 was be VBD cord-006870-f5w6fw6q 3454 16 " " `` cord-006870-f5w6fw6q 3454 17 somewhat somewhat RB cord-006870-f5w6fw6q 3454 18 helpful helpful JJ cord-006870-f5w6fw6q 3454 19 " " '' cord-006870-f5w6fw6q 3454 20 in in IN cord-006870-f5w6fw6q 3454 21 identifying identify VBG cord-006870-f5w6fw6q 3454 22 the the DT cord-006870-f5w6fw6q 3454 23 goals goal NNS cord-006870-f5w6fw6q 3454 24 of of IN cord-006870-f5w6fw6q 3454 25 the the DT cord-006870-f5w6fw6q 3454 26 rotation rotation NN cord-006870-f5w6fw6q 3454 27 . . . cord-006870-f5w6fw6q 3455 1 These these DT cord-006870-f5w6fw6q 3455 2 baseline baseline JJ cord-006870-f5w6fw6q 3455 3 measures measure NNS cord-006870-f5w6fw6q 3455 4 underscore underscore VBP cord-006870-f5w6fw6q 3455 5 the the DT cord-006870-f5w6fw6q 3455 6 importance importance NN cord-006870-f5w6fw6q 3455 7 of of IN cord-006870-f5w6fw6q 3455 8 structured structured JJ cord-006870-f5w6fw6q 3455 9 interventions intervention NNS cord-006870-f5w6fw6q 3455 10 , , , cord-006870-f5w6fw6q 3455 11 both both CC cord-006870-f5w6fw6q 3455 12 before before IN cord-006870-f5w6fw6q 3455 13 and and CC cord-006870-f5w6fw6q 3455 14 during during IN cord-006870-f5w6fw6q 3455 15 the the DT cord-006870-f5w6fw6q 3455 16 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 3455 17 rotation rotation NN cord-006870-f5w6fw6q 3455 18 , , , cord-006870-f5w6fw6q 3455 19 to to TO cord-006870-f5w6fw6q 3455 20 improve improve VB cord-006870-f5w6fw6q 3455 21 junior junior JJ cord-006870-f5w6fw6q 3455 22 resident resident JJ cord-006870-f5w6fw6q 3455 23 comfort comfort NN cord-006870-f5w6fw6q 3455 24 and and CC cord-006870-f5w6fw6q 3455 25 preparedness preparedness NN cord-006870-f5w6fw6q 3455 26 in in IN cord-006870-f5w6fw6q 3455 27 managing manage VBG cord-006870-f5w6fw6q 3455 28 neurologic neurologic JJ cord-006870-f5w6fw6q 3455 29 emergencies emergency NNS cord-006870-f5w6fw6q 3455 30 . . . cord-006870-f5w6fw6q 3456 1 Physician physician NN cord-006870-f5w6fw6q 3456 2 - - HYPH cord-006870-f5w6fw6q 3456 3 staffed staff VBN cord-006870-f5w6fw6q 3456 4 helicopter helicopter NN cord-006870-f5w6fw6q 3456 5 emergency emergency NN cord-006870-f5w6fw6q 3456 6 medical medical JJ cord-006870-f5w6fw6q 3456 7 services service NNS cord-006870-f5w6fw6q 3456 8 ( ( -LRB- cord-006870-f5w6fw6q 3456 9 HEMS HEMS NNP cord-006870-f5w6fw6q 3456 10 ) ) -RRB- cord-006870-f5w6fw6q 3456 11 are be VBP cord-006870-f5w6fw6q 3456 12 a a DT cord-006870-f5w6fw6q 3456 13 well well RB cord-006870-f5w6fw6q 3456 14 - - HYPH cord-006870-f5w6fw6q 3456 15 established establish VBN cord-006870-f5w6fw6q 3456 16 component component NN cord-006870-f5w6fw6q 3456 17 of of IN cord-006870-f5w6fw6q 3456 18 prehospital prehospital JJ cord-006870-f5w6fw6q 3456 19 care care NN cord-006870-f5w6fw6q 3456 20 in in IN cord-006870-f5w6fw6q 3456 21 Japan Japan NNP cord-006870-f5w6fw6q 3456 22 . . . cord-006870-f5w6fw6q 3457 1 However however RB cord-006870-f5w6fw6q 3457 2 , , , cord-006870-f5w6fw6q 3457 3 there there EX cord-006870-f5w6fw6q 3457 4 has have VBZ cord-006870-f5w6fw6q 3457 5 been be VBN cord-006870-f5w6fw6q 3457 6 no no DT cord-006870-f5w6fw6q 3457 7 report report NN cord-006870-f5w6fw6q 3457 8 on on IN cord-006870-f5w6fw6q 3457 9 HEMS HEMS NNP cord-006870-f5w6fw6q 3457 10 and and CC cord-006870-f5w6fw6q 3457 11 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3457 12 care care NN cord-006870-f5w6fw6q 3457 13 patients patient NNS cord-006870-f5w6fw6q 3457 14 . . . cord-006870-f5w6fw6q 3458 1 We -PRON- PRP cord-006870-f5w6fw6q 3458 2 studied study VBD cord-006870-f5w6fw6q 3458 3 characteristics characteristic NNS cord-006870-f5w6fw6q 3458 4 of of IN cord-006870-f5w6fw6q 3458 5 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3458 6 care care NN cord-006870-f5w6fw6q 3458 7 patients patient NNS cord-006870-f5w6fw6q 3458 8 who who WP cord-006870-f5w6fw6q 3458 9 were be VBD cord-006870-f5w6fw6q 3458 10 transported transport VBN cord-006870-f5w6fw6q 3458 11 by by IN cord-006870-f5w6fw6q 3458 12 HEMS HEMS NNP cord-006870-f5w6fw6q 3458 13 . . . cord-006870-f5w6fw6q 3459 1 We -PRON- PRP cord-006870-f5w6fw6q 3459 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 3459 3 evaluated evaluate VBD cord-006870-f5w6fw6q 3459 4 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3459 5 care care NN cord-006870-f5w6fw6q 3459 6 patients patient NNS cord-006870-f5w6fw6q 3459 7 who who WP cord-006870-f5w6fw6q 3459 8 were be VBD cord-006870-f5w6fw6q 3459 9 brought bring VBN cord-006870-f5w6fw6q 3459 10 to to IN cord-006870-f5w6fw6q 3459 11 our -PRON- PRP$ cord-006870-f5w6fw6q 3459 12 Emergency Emergency NNP cord-006870-f5w6fw6q 3459 13 and and CC cord-006870-f5w6fw6q 3459 14 Critical Critical NNP cord-006870-f5w6fw6q 3459 15 Care Care NNP cord-006870-f5w6fw6q 3459 16 Medical Medical NNP cord-006870-f5w6fw6q 3459 17 Center Center NNP cord-006870-f5w6fw6q 3459 18 ( ( -LRB- cord-006870-f5w6fw6q 3459 19 ECCMC ECCMC NNP cord-006870-f5w6fw6q 3459 20 ) ) -RRB- cord-006870-f5w6fw6q 3459 21 by by IN cord-006870-f5w6fw6q 3459 22 HEMS HEMS NNP cord-006870-f5w6fw6q 3459 23 between between IN cord-006870-f5w6fw6q 3459 24 January January NNP cord-006870-f5w6fw6q 3459 25 , , , cord-006870-f5w6fw6q 3459 26 2010 2010 CD cord-006870-f5w6fw6q 3459 27 and and CC cord-006870-f5w6fw6q 3459 28 March March NNP cord-006870-f5w6fw6q 3459 29 , , , cord-006870-f5w6fw6q 3459 30 2017 2017 CD cord-006870-f5w6fw6q 3459 31 . . . cord-006870-f5w6fw6q 3460 1 We -PRON- PRP cord-006870-f5w6fw6q 3460 2 excluded exclude VBD cord-006870-f5w6fw6q 3460 3 patients patient NNS cord-006870-f5w6fw6q 3460 4 in in IN cord-006870-f5w6fw6q 3460 5 whom whom WP cord-006870-f5w6fw6q 3460 6 the the DT cord-006870-f5w6fw6q 3460 7 outcome outcome NN cord-006870-f5w6fw6q 3460 8 was be VBD cord-006870-f5w6fw6q 3460 9 unknown unknown JJ cord-006870-f5w6fw6q 3460 10 , , , cord-006870-f5w6fw6q 3460 11 those those DT cord-006870-f5w6fw6q 3460 12 who who WP cord-006870-f5w6fw6q 3460 13 were be VBD cord-006870-f5w6fw6q 3460 14 transported transport VBN cord-006870-f5w6fw6q 3460 15 to to IN cord-006870-f5w6fw6q 3460 16 other other JJ cord-006870-f5w6fw6q 3460 17 hospitals hospital NNS cord-006870-f5w6fw6q 3460 18 or or CC cord-006870-f5w6fw6q 3460 19 between between IN cord-006870-f5w6fw6q 3460 20 facilities facility NNS cord-006870-f5w6fw6q 3460 21 . . . cord-006870-f5w6fw6q 3461 1 Of of IN cord-006870-f5w6fw6q 3461 2 4216 4216 CD cord-006870-f5w6fw6q 3461 3 _SP cord-006870-f5w6fw6q 3462 1 The the DT cord-006870-f5w6fw6q 3462 2 most most RBS cord-006870-f5w6fw6q 3462 3 important important JJ cord-006870-f5w6fw6q 3462 4 role role NN cord-006870-f5w6fw6q 3462 5 of of IN cord-006870-f5w6fw6q 3462 6 HEMS HEMS NNP cord-006870-f5w6fw6q 3462 7 is be VBZ cord-006870-f5w6fw6q 3462 8 rapid rapid JJ cord-006870-f5w6fw6q 3462 9 transportation transportation NN cord-006870-f5w6fw6q 3462 10 of of IN cord-006870-f5w6fw6q 3462 11 a a DT cord-006870-f5w6fw6q 3462 12 flight flight NN cord-006870-f5w6fw6q 3462 13 medical medical JJ cord-006870-f5w6fw6q 3462 14 team team NN cord-006870-f5w6fw6q 3462 15 to to IN cord-006870-f5w6fw6q 3462 16 the the DT cord-006870-f5w6fw6q 3462 17 scene scene NN cord-006870-f5w6fw6q 3462 18 to to TO cord-006870-f5w6fw6q 3462 19 provide provide VB cord-006870-f5w6fw6q 3462 20 immediate immediate JJ cord-006870-f5w6fw6q 3462 21 , , , cord-006870-f5w6fw6q 3462 22 lifesaving lifesaving JJ cord-006870-f5w6fw6q 3462 23 medical medical JJ cord-006870-f5w6fw6q 3462 24 treatment treatment NN cord-006870-f5w6fw6q 3462 25 . . . cord-006870-f5w6fw6q 3463 1 We -PRON- PRP cord-006870-f5w6fw6q 3463 2 found find VBD cord-006870-f5w6fw6q 3463 3 that that IN cord-006870-f5w6fw6q 3463 4 half half NN cord-006870-f5w6fw6q 3463 5 of of IN cord-006870-f5w6fw6q 3463 6 patients patient NNS cord-006870-f5w6fw6q 3463 7 admitted admit VBN cord-006870-f5w6fw6q 3463 8 to to IN cord-006870-f5w6fw6q 3463 9 our -PRON- PRP$ cord-006870-f5w6fw6q 3463 10 hospital hospital NN cord-006870-f5w6fw6q 3463 11 by by IN cord-006870-f5w6fw6q 3463 12 HEMS HEMS NNPS cord-006870-f5w6fw6q 3463 13 were be VBD cord-006870-f5w6fw6q 3463 14 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3463 15 care care NN cord-006870-f5w6fw6q 3463 16 patients patient NNS cord-006870-f5w6fw6q 3463 17 . . . cord-006870-f5w6fw6q 3464 1 As as IN cord-006870-f5w6fw6q 3464 2 proposed propose VBN cord-006870-f5w6fw6q 3464 3 in in IN cord-006870-f5w6fw6q 3464 4 the the DT cord-006870-f5w6fw6q 3464 5 ENLS enl NNS cord-006870-f5w6fw6q 3464 6 of of IN cord-006870-f5w6fw6q 3464 7 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3464 8 care care NN cord-006870-f5w6fw6q 3464 9 society society NN cord-006870-f5w6fw6q 3464 10 , , , cord-006870-f5w6fw6q 3464 11 HEMS HEMS NNP cord-006870-f5w6fw6q 3464 12 is be VBZ cord-006870-f5w6fw6q 3464 13 considered consider VBN cord-006870-f5w6fw6q 3464 14 useful useful JJ cord-006870-f5w6fw6q 3464 15 to to TO cord-006870-f5w6fw6q 3464 16 allow allow VB cord-006870-f5w6fw6q 3464 17 neuro neuro NNP cord-006870-f5w6fw6q 3464 18 - - HYPH cord-006870-f5w6fw6q 3464 19 emergency emergency NN cord-006870-f5w6fw6q 3464 20 patients patient NNS cord-006870-f5w6fw6q 3464 21 to to TO cord-006870-f5w6fw6q 3464 22 receive receive VB cord-006870-f5w6fw6q 3464 23 the the DT cord-006870-f5w6fw6q 3464 24 best good JJS cord-006870-f5w6fw6q 3464 25 care care NN cord-006870-f5w6fw6q 3464 26 in in IN cord-006870-f5w6fw6q 3464 27 the the DT cord-006870-f5w6fw6q 3464 28 first first JJ cord-006870-f5w6fw6q 3464 29 hour hour NN cord-006870-f5w6fw6q 3464 30 . . . cord-006870-f5w6fw6q 3465 1 Optic optic JJ cord-006870-f5w6fw6q 3465 2 Nerve nerve NN cord-006870-f5w6fw6q 3465 3 Sheath Sheath NNP cord-006870-f5w6fw6q 3465 4 Diameter Diameter NNP cord-006870-f5w6fw6q 3465 5 ( ( -LRB- cord-006870-f5w6fw6q 3465 6 ONSD ONSD NNP cord-006870-f5w6fw6q 3465 7 ) ) -RRB- cord-006870-f5w6fw6q 3465 8 measurement measurement NN cord-006870-f5w6fw6q 3465 9 using use VBG cord-006870-f5w6fw6q 3465 10 ocular ocular JJ cord-006870-f5w6fw6q 3465 11 ultrasound ultrasound NN cord-006870-f5w6fw6q 3465 12 has have VBZ cord-006870-f5w6fw6q 3465 13 been be VBN cord-006870-f5w6fw6q 3465 14 shown show VBN cord-006870-f5w6fw6q 3465 15 to to TO cord-006870-f5w6fw6q 3465 16 accurately accurately RB cord-006870-f5w6fw6q 3465 17 detect detect VB cord-006870-f5w6fw6q 3465 18 elevated elevate VBN cord-006870-f5w6fw6q 3465 19 Intracranial Intracranial NNP cord-006870-f5w6fw6q 3465 20 Pressure Pressure NNP cord-006870-f5w6fw6q 3465 21 ( ( -LRB- cord-006870-f5w6fw6q 3465 22 ICP ICP NNP cord-006870-f5w6fw6q 3465 23 ) ) -RRB- cord-006870-f5w6fw6q 3465 24 , , , cord-006870-f5w6fw6q 3465 25 but but CC cord-006870-f5w6fw6q 3465 26 does do VBZ cord-006870-f5w6fw6q 3465 27 require require VB cord-006870-f5w6fw6q 3465 28 specialized specialized JJ cord-006870-f5w6fw6q 3465 29 training training NN cord-006870-f5w6fw6q 3465 30 . . . cord-006870-f5w6fw6q 3466 1 Variations variation NNS cord-006870-f5w6fw6q 3466 2 in in IN cord-006870-f5w6fw6q 3466 3 the the DT cord-006870-f5w6fw6q 3466 4 optimal optimal JJ cord-006870-f5w6fw6q 3466 5 ONSD ONSD NNP cord-006870-f5w6fw6q 3466 6 threshold threshold NN cord-006870-f5w6fw6q 3466 7 for for IN cord-006870-f5w6fw6q 3466 8 detection detection NN cord-006870-f5w6fw6q 3466 9 of of IN cord-006870-f5w6fw6q 3466 10 elevated elevated JJ cord-006870-f5w6fw6q 3466 11 ICP ICP NNP cord-006870-f5w6fw6q 3466 12 in in IN cord-006870-f5w6fw6q 3466 13 the the DT cord-006870-f5w6fw6q 3466 14 literature literature NN cord-006870-f5w6fw6q 3466 15 limits limit VBZ cord-006870-f5w6fw6q 3466 16 clinical clinical JJ cord-006870-f5w6fw6q 3466 17 utility utility NN cord-006870-f5w6fw6q 3466 18 , , , cord-006870-f5w6fw6q 3466 19 and and CC cord-006870-f5w6fw6q 3466 20 may may MD cord-006870-f5w6fw6q 3466 21 reflect reflect VB cord-006870-f5w6fw6q 3466 22 heterogeneity heterogeneity NN cord-006870-f5w6fw6q 3466 23 in in IN cord-006870-f5w6fw6q 3466 24 manual manual JJ cord-006870-f5w6fw6q 3466 25 measurement measurement NN cord-006870-f5w6fw6q 3466 26 techniques technique NNS cord-006870-f5w6fw6q 3466 27 . . . cord-006870-f5w6fw6q 3467 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3467 2 objective objective NN cord-006870-f5w6fw6q 3467 3 was be VBD cord-006870-f5w6fw6q 3467 4 to to TO cord-006870-f5w6fw6q 3467 5 develop develop VB cord-006870-f5w6fw6q 3467 6 , , , cord-006870-f5w6fw6q 3467 7 and and CC cord-006870-f5w6fw6q 3467 8 validate validate VB cord-006870-f5w6fw6q 3467 9 against against IN cord-006870-f5w6fw6q 3467 10 expert expert JJ cord-006870-f5w6fw6q 3467 11 measurement measurement NN cord-006870-f5w6fw6q 3467 12 , , , cord-006870-f5w6fw6q 3467 13 an an DT cord-006870-f5w6fw6q 3467 14 image image NN cord-006870-f5w6fw6q 3467 15 - - HYPH cord-006870-f5w6fw6q 3467 16 analysis analysis NN cord-006870-f5w6fw6q 3467 17 algorithm algorithm NN cord-006870-f5w6fw6q 3467 18 for for IN cord-006870-f5w6fw6q 3467 19 ONSD ONSD NNP cord-006870-f5w6fw6q 3467 20 measurement measurement NN cord-006870-f5w6fw6q 3467 21 to to TO cord-006870-f5w6fw6q 3467 22 facilitate facilitate VB cord-006870-f5w6fw6q 3467 23 standardization standardization NN cord-006870-f5w6fw6q 3467 24 and and CC cord-006870-f5w6fw6q 3467 25 ease ease NN cord-006870-f5w6fw6q 3467 26 of of IN cord-006870-f5w6fw6q 3467 27 use use NN cord-006870-f5w6fw6q 3467 28 of of IN cord-006870-f5w6fw6q 3467 29 this this DT cord-006870-f5w6fw6q 3467 30 technique technique NN cord-006870-f5w6fw6q 3467 31 . . . cord-006870-f5w6fw6q 3468 1 Consecutive consecutive JJ cord-006870-f5w6fw6q 3468 2 patients patient NNS cord-006870-f5w6fw6q 3468 3 with with IN cord-006870-f5w6fw6q 3468 4 acute acute JJ cord-006870-f5w6fw6q 3468 5 brain brain NN cord-006870-f5w6fw6q 3468 6 injury injury NN cord-006870-f5w6fw6q 3468 7 admitted admit VBN cord-006870-f5w6fw6q 3468 8 to to IN cord-006870-f5w6fw6q 3468 9 the the DT cord-006870-f5w6fw6q 3468 10 neurointensive neurointensive NNP cord-006870-f5w6fw6q 3468 11 care care NN cord-006870-f5w6fw6q 3468 12 unit unit NN cord-006870-f5w6fw6q 3468 13 underwent undergo VBD cord-006870-f5w6fw6q 3468 14 ocular ocular JJ cord-006870-f5w6fw6q 3468 15 ultrasound ultrasound NN cord-006870-f5w6fw6q 3468 16 with with IN cord-006870-f5w6fw6q 3468 17 a a DT cord-006870-f5w6fw6q 3468 18 multipurpose multipurpose JJ cord-006870-f5w6fw6q 3468 19 point point NN cord-006870-f5w6fw6q 3468 20 - - HYPH cord-006870-f5w6fw6q 3468 21 of of IN cord-006870-f5w6fw6q 3468 22 - - HYPH cord-006870-f5w6fw6q 3468 23 care care NN cord-006870-f5w6fw6q 3468 24 ultrasound ultrasound NN cord-006870-f5w6fw6q 3468 25 machine machine NN cord-006870-f5w6fw6q 3468 26 . . . cord-006870-f5w6fw6q 3469 1 A a DT cord-006870-f5w6fw6q 3469 2 6-second 6-second CD cord-006870-f5w6fw6q 3469 3 video video NN cord-006870-f5w6fw6q 3469 4 was be VBD cord-006870-f5w6fw6q 3469 5 recorded record VBN cord-006870-f5w6fw6q 3469 6 from from IN cord-006870-f5w6fw6q 3469 7 each each DT cord-006870-f5w6fw6q 3469 8 eye eye NN cord-006870-f5w6fw6q 3469 9 in in IN cord-006870-f5w6fw6q 3469 10 the the DT cord-006870-f5w6fw6q 3469 11 axial axial JJ cord-006870-f5w6fw6q 3469 12 plane plane NN cord-006870-f5w6fw6q 3469 13 and and CC cord-006870-f5w6fw6q 3469 14 downloaded download VBN cord-006870-f5w6fw6q 3469 15 in in IN cord-006870-f5w6fw6q 3469 16 DICOM DICOM NNP cord-006870-f5w6fw6q 3469 17 format format NN cord-006870-f5w6fw6q 3469 18 . . . cord-006870-f5w6fw6q 3470 1 The the DT cord-006870-f5w6fw6q 3470 2 ONSD ONSD NNP cord-006870-f5w6fw6q 3470 3 measurement measurement NN cord-006870-f5w6fw6q 3470 4 algorithm algorithm NN cord-006870-f5w6fw6q 3470 5 was be VBD cord-006870-f5w6fw6q 3470 6 as as IN cord-006870-f5w6fw6q 3470 7 follows follow VBZ cord-006870-f5w6fw6q 3470 8 . . . cord-006870-f5w6fw6q 3471 1 An an DT cord-006870-f5w6fw6q 3471 2 average average NN cord-006870-f5w6fw6q 3471 3 of of IN cord-006870-f5w6fw6q 3471 4 images image NNS cord-006870-f5w6fw6q 3471 5 was be VBD cord-006870-f5w6fw6q 3471 6 calculated calculate VBN cord-006870-f5w6fw6q 3471 7 using use VBG cord-006870-f5w6fw6q 3471 8 non non JJ cord-006870-f5w6fw6q 3471 9 - - JJ cord-006870-f5w6fw6q 3471 10 overlapped overlapped JJ cord-006870-f5w6fw6q 3471 11 segments segment NNS cord-006870-f5w6fw6q 3471 12 of of IN cord-006870-f5w6fw6q 3471 13 the the DT cord-006870-f5w6fw6q 3471 14 image image NN cord-006870-f5w6fw6q 3471 15 sequence sequence NN cord-006870-f5w6fw6q 3471 16 . . . cord-006870-f5w6fw6q 3472 1 A a DT cord-006870-f5w6fw6q 3472 2 line line NN cord-006870-f5w6fw6q 3472 3 integral integral JJ cord-006870-f5w6fw6q 3472 4 was be VBD cord-006870-f5w6fw6q 3472 5 performed perform VBN cord-006870-f5w6fw6q 3472 6 to to TO cord-006870-f5w6fw6q 3472 7 estimate estimate VB cord-006870-f5w6fw6q 3472 8 the the DT cord-006870-f5w6fw6q 3472 9 border border NN cord-006870-f5w6fw6q 3472 10 of of IN cord-006870-f5w6fw6q 3472 11 the the DT cord-006870-f5w6fw6q 3472 12 region region NN cord-006870-f5w6fw6q 3472 13 of of IN cord-006870-f5w6fw6q 3472 14 interest interest NN cord-006870-f5w6fw6q 3472 15 ( ( -LRB- cord-006870-f5w6fw6q 3472 16 ROI ROI NNP cord-006870-f5w6fw6q 3472 17 ) ) -RRB- cord-006870-f5w6fw6q 3472 18 , , , cord-006870-f5w6fw6q 3472 19 the the DT cord-006870-f5w6fw6q 3472 20 globe globe NN cord-006870-f5w6fw6q 3472 21 . . . cord-006870-f5w6fw6q 3473 1 The the DT cord-006870-f5w6fw6q 3473 2 ROI ROI NNP cord-006870-f5w6fw6q 3473 3 orientation orientation NN cord-006870-f5w6fw6q 3473 4 and and CC cord-006870-f5w6fw6q 3473 5 globe globe NN cord-006870-f5w6fw6q 3473 6 point point NN cord-006870-f5w6fw6q 3473 7 of of IN cord-006870-f5w6fw6q 3473 8 the the DT cord-006870-f5w6fw6q 3473 9 segmented segmented JJ cord-006870-f5w6fw6q 3473 10 region region NN cord-006870-f5w6fw6q 3473 11 were be VBD cord-006870-f5w6fw6q 3473 12 established establish VBN cord-006870-f5w6fw6q 3473 13 , , , cord-006870-f5w6fw6q 3473 14 then then RB cord-006870-f5w6fw6q 3473 15 a a DT cord-006870-f5w6fw6q 3473 16 point point NN cord-006870-f5w6fw6q 3473 17 3 3 CD cord-006870-f5w6fw6q 3473 18 mm mm NN cord-006870-f5w6fw6q 3473 19 posterior posterior NN cord-006870-f5w6fw6q 3473 20 to to IN cord-006870-f5w6fw6q 3473 21 the the DT cord-006870-f5w6fw6q 3473 22 globe globe NN cord-006870-f5w6fw6q 3473 23 point point NN cord-006870-f5w6fw6q 3473 24 identified identify VBN cord-006870-f5w6fw6q 3473 25 . . . cord-006870-f5w6fw6q 3474 1 The the DT cord-006870-f5w6fw6q 3474 2 ONSD ONSD NNP cord-006870-f5w6fw6q 3474 3 was be VBD cord-006870-f5w6fw6q 3474 4 measured measure VBN cord-006870-f5w6fw6q 3474 5 at at IN cord-006870-f5w6fw6q 3474 6 this this DT cord-006870-f5w6fw6q 3474 7 point point NN cord-006870-f5w6fw6q 3474 8 . . . cord-006870-f5w6fw6q 3475 1 Manual Manual NNP cord-006870-f5w6fw6q 3475 2 ONSD ONSD NNP cord-006870-f5w6fw6q 3475 3 measurement measurement NN cord-006870-f5w6fw6q 3475 4 was be VBD cord-006870-f5w6fw6q 3475 5 performed perform VBN cord-006870-f5w6fw6q 3475 6 separately separately RB cord-006870-f5w6fw6q 3475 7 from from IN cord-006870-f5w6fw6q 3475 8 the the DT cord-006870-f5w6fw6q 3475 9 DICOM DICOM NNP cord-006870-f5w6fw6q 3475 10 videos video NNS cord-006870-f5w6fw6q 3475 11 by by IN cord-006870-f5w6fw6q 3475 12 an an DT cord-006870-f5w6fw6q 3475 13 expert expert NN cord-006870-f5w6fw6q 3475 14 blinded blind VBN cord-006870-f5w6fw6q 3475 15 to to IN cord-006870-f5w6fw6q 3475 16 the the DT cord-006870-f5w6fw6q 3475 17 algorithm algorithm NN cord-006870-f5w6fw6q 3475 18 measurement measurement NN cord-006870-f5w6fw6q 3475 19 . . . cord-006870-f5w6fw6q 3476 1 An an DT cord-006870-f5w6fw6q 3476 2 Intraclass Intraclass NNP cord-006870-f5w6fw6q 3476 3 Coefficient Coefficient NNP cord-006870-f5w6fw6q 3476 4 ( ( -LRB- cord-006870-f5w6fw6q 3476 5 ICC ICC NNP cord-006870-f5w6fw6q 3476 6 ) ) -RRB- cord-006870-f5w6fw6q 3476 7 was be VBD cord-006870-f5w6fw6q 3476 8 calculated calculate VBN cord-006870-f5w6fw6q 3476 9 for for IN cord-006870-f5w6fw6q 3476 10 absolute absolute JJ cord-006870-f5w6fw6q 3476 11 agreement agreement NN cord-006870-f5w6fw6q 3476 12 between between IN cord-006870-f5w6fw6q 3476 13 highest high JJS cord-006870-f5w6fw6q 3476 14 ONSD ONSD NNS cord-006870-f5w6fw6q 3476 15 measured measure VBN cord-006870-f5w6fw6q 3476 16 by by IN cord-006870-f5w6fw6q 3476 17 the the DT cord-006870-f5w6fw6q 3476 18 algorithm algorithm NN cord-006870-f5w6fw6q 3476 19 and and CC cord-006870-f5w6fw6q 3476 20 expert expert JJ cord-006870-f5w6fw6q 3476 21 manual manual JJ cord-006870-f5w6fw6q 3476 22 measurement measurement NN cord-006870-f5w6fw6q 3476 23 . . . cord-006870-f5w6fw6q 3477 1 A a DT cord-006870-f5w6fw6q 3477 2 total total NN cord-006870-f5w6fw6q 3477 3 of of IN cord-006870-f5w6fw6q 3477 4 27 27 CD cord-006870-f5w6fw6q 3477 5 patients patient NNS cord-006870-f5w6fw6q 3477 6 with with IN cord-006870-f5w6fw6q 3477 7 acute acute JJ cord-006870-f5w6fw6q 3477 8 brain brain NN cord-006870-f5w6fw6q 3477 9 injury injury NN cord-006870-f5w6fw6q 3477 10 underwent undergo VBD cord-006870-f5w6fw6q 3477 11 ocular ocular JJ cord-006870-f5w6fw6q 3477 12 ultrasound ultrasound NN cord-006870-f5w6fw6q 3477 13 . . . cord-006870-f5w6fw6q 3478 1 The the DT cord-006870-f5w6fw6q 3478 2 ICC ICC NNP cord-006870-f5w6fw6q 3478 3 for for IN cord-006870-f5w6fw6q 3478 4 absolute absolute JJ cord-006870-f5w6fw6q 3478 5 agreement agreement NN cord-006870-f5w6fw6q 3478 6 between between IN cord-006870-f5w6fw6q 3478 7 algorithm algorithm NN cord-006870-f5w6fw6q 3478 8 ( ( -LRB- cord-006870-f5w6fw6q 3478 9 median median NN cord-006870-f5w6fw6q 3478 10 0.66 0.66 CD cord-006870-f5w6fw6q 3478 11 , , , cord-006870-f5w6fw6q 3478 12 Interquartile Interquartile NNP cord-006870-f5w6fw6q 3478 13 Range Range NNP cord-006870-f5w6fw6q 3478 14 0.61 0.61 CD cord-006870-f5w6fw6q 3478 15 - - HYPH cord-006870-f5w6fw6q 3478 16 0.71 0.71 CD cord-006870-f5w6fw6q 3478 17 ) ) -RRB- cord-006870-f5w6fw6q 3478 18 and and CC cord-006870-f5w6fw6q 3478 19 manual manual JJ cord-006870-f5w6fw6q 3478 20 expert expert NN cord-006870-f5w6fw6q 3478 21 ( ( -LRB- cord-006870-f5w6fw6q 3478 22 median median JJ cord-006870-f5w6fw6q 3478 23 0.63 0.63 CD cord-006870-f5w6fw6q 3478 24 , , , cord-006870-f5w6fw6q 3478 25 0.61 0.61 CD cord-006870-f5w6fw6q 3478 26 - - SYM cord-006870-f5w6fw6q 3478 27 0.71 0.71 CD cord-006870-f5w6fw6q 3478 28 ) ) -RRB- cord-006870-f5w6fw6q 3478 29 highest high JJS cord-006870-f5w6fw6q 3478 30 ONSD ONSD NNP cord-006870-f5w6fw6q 3478 31 measurement measurement NN cord-006870-f5w6fw6q 3478 32 was be VBD cord-006870-f5w6fw6q 3478 33 0.68 0.68 CD cord-006870-f5w6fw6q 3478 34 ( ( -LRB- cord-006870-f5w6fw6q 3478 35 95 95 CD cord-006870-f5w6fw6q 3478 36 % % NN cord-006870-f5w6fw6q 3478 37 Confidence confidence NN cord-006870-f5w6fw6q 3478 38 Interval Interval NNP cord-006870-f5w6fw6q 3478 39 0.31 0.31 CD cord-006870-f5w6fw6q 3478 40 - - HYPH cord-006870-f5w6fw6q 3478 41 0.85 0.85 CD cord-006870-f5w6fw6q 3478 42 ) ) -RRB- cord-006870-f5w6fw6q 3478 43 . . . cord-006870-f5w6fw6q 3479 1 An an DT cord-006870-f5w6fw6q 3479 2 algorithm algorithm NN cord-006870-f5w6fw6q 3479 3 for for IN cord-006870-f5w6fw6q 3479 4 automated automate VBN cord-006870-f5w6fw6q 3479 5 measurement measurement NN cord-006870-f5w6fw6q 3479 6 of of IN cord-006870-f5w6fw6q 3479 7 ONSD ONSD NNP cord-006870-f5w6fw6q 3479 8 was be VBD cord-006870-f5w6fw6q 3479 9 developed develop VBN cord-006870-f5w6fw6q 3479 10 and and CC cord-006870-f5w6fw6q 3479 11 demonstrated demonstrate VBN cord-006870-f5w6fw6q 3479 12 good good JJ cord-006870-f5w6fw6q 3479 13 inter inter JJ cord-006870-f5w6fw6q 3479 14 - - JJ cord-006870-f5w6fw6q 3479 15 rater rater JJ cord-006870-f5w6fw6q 3479 16 agreement agreement NN cord-006870-f5w6fw6q 3479 17 with with IN cord-006870-f5w6fw6q 3479 18 expert expert JJ cord-006870-f5w6fw6q 3479 19 measurement measurement NN cord-006870-f5w6fw6q 3479 20 , , , cord-006870-f5w6fw6q 3479 21 although although IN cord-006870-f5w6fw6q 3479 22 further further JJ cord-006870-f5w6fw6q 3479 23 refinement refinement NN cord-006870-f5w6fw6q 3479 24 is be VBZ cord-006870-f5w6fw6q 3479 25 required require VBN cord-006870-f5w6fw6q 3479 26 . . . cord-006870-f5w6fw6q 3480 1 Automated automate VBN cord-006870-f5w6fw6q 3480 2 measurement measurement NN cord-006870-f5w6fw6q 3480 3 may may MD cord-006870-f5w6fw6q 3480 4 help help VB cord-006870-f5w6fw6q 3480 5 standardize standardize VB cord-006870-f5w6fw6q 3480 6 and and CC cord-006870-f5w6fw6q 3480 7 simplify simplify VB cord-006870-f5w6fw6q 3480 8 a a DT cord-006870-f5w6fw6q 3480 9 promising promising JJ cord-006870-f5w6fw6q 3480 10 noninvasive noninvasive JJ cord-006870-f5w6fw6q 3480 11 bedside bedside NN cord-006870-f5w6fw6q 3480 12 tool tool NN cord-006870-f5w6fw6q 3480 13 for for IN cord-006870-f5w6fw6q 3480 14 the the DT cord-006870-f5w6fw6q 3480 15 detection detection NN cord-006870-f5w6fw6q 3480 16 of of IN cord-006870-f5w6fw6q 3480 17 elevated elevated JJ cord-006870-f5w6fw6q 3480 18 ICP ICP NNP cord-006870-f5w6fw6q 3480 19 . . . cord-006870-f5w6fw6q 3481 1 After after IN cord-006870-f5w6fw6q 3481 2 transition transition NN cord-006870-f5w6fw6q 3481 3 to to IN cord-006870-f5w6fw6q 3481 4 electronic electronic JJ cord-006870-f5w6fw6q 3481 5 health health NN cord-006870-f5w6fw6q 3481 6 record record NN cord-006870-f5w6fw6q 3481 7 ( ( -LRB- cord-006870-f5w6fw6q 3481 8 EHR EHR NNP cord-006870-f5w6fw6q 3481 9 ) ) -RRB- cord-006870-f5w6fw6q 3481 10 , , , cord-006870-f5w6fw6q 3481 11 transition transition NN cord-006870-f5w6fw6q 3481 12 to to IN cord-006870-f5w6fw6q 3481 13 inpatient inpatient JJ cord-006870-f5w6fw6q 3481 14 hospice hospice NN cord-006870-f5w6fw6q 3481 15 required require VBD cord-006870-f5w6fw6q 3481 16 a a DT cord-006870-f5w6fw6q 3481 17 separate separate JJ cord-006870-f5w6fw6q 3481 18 encounter encounter NN cord-006870-f5w6fw6q 3481 19 to to TO cord-006870-f5w6fw6q 3481 20 account account VB cord-006870-f5w6fw6q 3481 21 for for IN cord-006870-f5w6fw6q 3481 22 change change NN cord-006870-f5w6fw6q 3481 23 in in IN cord-006870-f5w6fw6q 3481 24 insurance insurance NN cord-006870-f5w6fw6q 3481 25 payer payer NN cord-006870-f5w6fw6q 3481 26 in in IN cord-006870-f5w6fw6q 3481 27 our -PRON- PRP$ cord-006870-f5w6fw6q 3481 28 neuroICU neuroicu NN cord-006870-f5w6fw6q 3481 29 . . . cord-006870-f5w6fw6q 3482 1 This this DT cord-006870-f5w6fw6q 3482 2 negatively negatively RB cord-006870-f5w6fw6q 3482 3 affected affect VBN cord-006870-f5w6fw6q 3482 4 completed complete VBN cord-006870-f5w6fw6q 3482 5 transitions transition NNS cord-006870-f5w6fw6q 3482 6 and and CC cord-006870-f5w6fw6q 3482 7 hence hence RB cord-006870-f5w6fw6q 3482 8 patient patient RB cord-006870-f5w6fw6q 3482 9 - - HYPH cord-006870-f5w6fw6q 3482 10 centered center VBN cord-006870-f5w6fw6q 3482 11 care care NN cord-006870-f5w6fw6q 3482 12 . . . cord-006870-f5w6fw6q 3483 1 The the DT cord-006870-f5w6fw6q 3483 2 focus focus NN cord-006870-f5w6fw6q 3483 3 of of IN cord-006870-f5w6fw6q 3483 4 this this DT cord-006870-f5w6fw6q 3483 5 quality quality NN cord-006870-f5w6fw6q 3483 6 improvement improvement NN cord-006870-f5w6fw6q 3483 7 project project NN cord-006870-f5w6fw6q 3483 8 was be VBD cord-006870-f5w6fw6q 3483 9 to to TO cord-006870-f5w6fw6q 3483 10 define define VB cord-006870-f5w6fw6q 3483 11 the the DT cord-006870-f5w6fw6q 3483 12 new new JJ cord-006870-f5w6fw6q 3483 13 process process NN cord-006870-f5w6fw6q 3483 14 , , , cord-006870-f5w6fw6q 3483 15 improve improve VB cord-006870-f5w6fw6q 3483 16 outcomes outcome NNS cord-006870-f5w6fw6q 3483 17 , , , cord-006870-f5w6fw6q 3483 18 and and CC cord-006870-f5w6fw6q 3483 19 identify identify VB cord-006870-f5w6fw6q 3483 20 further further JJ cord-006870-f5w6fw6q 3483 21 opportunities opportunity NNS cord-006870-f5w6fw6q 3483 22 . . . cord-006870-f5w6fw6q 3484 1 The the DT cord-006870-f5w6fw6q 3484 2 Quality Quality NNP cord-006870-f5w6fw6q 3484 3 Improvement improvement NN cord-006870-f5w6fw6q 3484 4 method method NN cord-006870-f5w6fw6q 3484 5 " " `` cord-006870-f5w6fw6q 3484 6 Plan plan NN cord-006870-f5w6fw6q 3484 7 - - HYPH cord-006870-f5w6fw6q 3484 8 Do Do NNP cord-006870-f5w6fw6q 3484 9 - - HYPH cord-006870-f5w6fw6q 3484 10 Study Study NNP cord-006870-f5w6fw6q 3484 11 - - HYPH cord-006870-f5w6fw6q 3484 12 Act Act NNP cord-006870-f5w6fw6q 3484 13 " " '' cord-006870-f5w6fw6q 3484 14 was be VBD cord-006870-f5w6fw6q 3484 15 employed employ VBN cord-006870-f5w6fw6q 3484 16 for for IN cord-006870-f5w6fw6q 3484 17 this this DT cord-006870-f5w6fw6q 3484 18 work work NN cord-006870-f5w6fw6q 3484 19 within within IN cord-006870-f5w6fw6q 3484 20 a a DT cord-006870-f5w6fw6q 3484 21 30-bed 30-bed CD cord-006870-f5w6fw6q 3484 22 Neuro Neuro NNP cord-006870-f5w6fw6q 3484 23 - - HYPH cord-006870-f5w6fw6q 3484 24 ICU ICU NNP cord-006870-f5w6fw6q 3484 25 at at IN cord-006870-f5w6fw6q 3484 26 a a DT cord-006870-f5w6fw6q 3484 27 large large JJ cord-006870-f5w6fw6q 3484 28 Academic Academic NNP cord-006870-f5w6fw6q 3484 29 Medical Medical NNP cord-006870-f5w6fw6q 3484 30 Center Center NNP cord-006870-f5w6fw6q 3484 31 . . . cord-006870-f5w6fw6q 3485 1 We -PRON- PRP cord-006870-f5w6fw6q 3485 2 assessed assess VBD cord-006870-f5w6fw6q 3485 3 the the DT cord-006870-f5w6fw6q 3485 4 current current JJ cord-006870-f5w6fw6q 3485 5 state state NN cord-006870-f5w6fw6q 3485 6 ( ( -LRB- cord-006870-f5w6fw6q 3485 7 not not RB cord-006870-f5w6fw6q 3485 8 enabling enable VBG cord-006870-f5w6fw6q 3485 9 transition transition NN cord-006870-f5w6fw6q 3485 10 to to IN cord-006870-f5w6fw6q 3485 11 inpatient inpatient JJ cord-006870-f5w6fw6q 3485 12 hospice hospice NN cord-006870-f5w6fw6q 3485 13 ) ) -RRB- cord-006870-f5w6fw6q 3485 14 and and CC cord-006870-f5w6fw6q 3485 15 the the DT cord-006870-f5w6fw6q 3485 16 desired desire VBN cord-006870-f5w6fw6q 3485 17 state state NN cord-006870-f5w6fw6q 3485 18 ( ( -LRB- cord-006870-f5w6fw6q 3485 19 enrollment enrollment NN cord-006870-f5w6fw6q 3485 20 in in IN cord-006870-f5w6fw6q 3485 21 hospice hospice NN cord-006870-f5w6fw6q 3485 22 during during IN cord-006870-f5w6fw6q 3485 23 inpatient inpatient JJ cord-006870-f5w6fw6q 3485 24 stay stay NN cord-006870-f5w6fw6q 3485 25 ) ) -RRB- cord-006870-f5w6fw6q 3485 26 . . . cord-006870-f5w6fw6q 3486 1 A a DT cord-006870-f5w6fw6q 3486 2 new new JJ cord-006870-f5w6fw6q 3486 3 process process NN cord-006870-f5w6fw6q 3486 4 was be VBD cord-006870-f5w6fw6q 3486 5 created create VBN cord-006870-f5w6fw6q 3486 6 using use VBG cord-006870-f5w6fw6q 3486 7 an an DT cord-006870-f5w6fw6q 3486 8 EHR EHR NNP cord-006870-f5w6fw6q 3486 9 Discharge Discharge NNP cord-006870-f5w6fw6q 3486 10 Navigator Navigator NNP cord-006870-f5w6fw6q 3486 11 , , , cord-006870-f5w6fw6q 3486 12 coordinating coordinate VBG cord-006870-f5w6fw6q 3486 13 all all DT cord-006870-f5w6fw6q 3486 14 relevant relevant JJ cord-006870-f5w6fw6q 3486 15 stakeholder stakeholder NN cord-006870-f5w6fw6q 3486 16 groups group NNS cord-006870-f5w6fw6q 3486 17 ( ( -LRB- cord-006870-f5w6fw6q 3486 18 patient patient NN cord-006870-f5w6fw6q 3486 19 / / SYM cord-006870-f5w6fw6q 3486 20 caregiver caregiver NN cord-006870-f5w6fw6q 3486 21 , , , cord-006870-f5w6fw6q 3486 22 nurse nurse NN cord-006870-f5w6fw6q 3486 23 , , , cord-006870-f5w6fw6q 3486 24 pharmacist pharmacist NN cord-006870-f5w6fw6q 3486 25 , , , cord-006870-f5w6fw6q 3486 26 bed bed NN cord-006870-f5w6fw6q 3486 27 control control NN cord-006870-f5w6fw6q 3486 28 , , , cord-006870-f5w6fw6q 3486 29 physician physician NN cord-006870-f5w6fw6q 3486 30 , , , cord-006870-f5w6fw6q 3486 31 ) ) -RRB- cord-006870-f5w6fw6q 3486 32 . . . cord-006870-f5w6fw6q 3487 1 In in IN cord-006870-f5w6fw6q 3487 2 addition addition NN cord-006870-f5w6fw6q 3487 3 , , , cord-006870-f5w6fw6q 3487 4 standard standard JJ cord-006870-f5w6fw6q 3487 5 methodology methodology NN cord-006870-f5w6fw6q 3487 6 for for IN cord-006870-f5w6fw6q 3487 7 unit unit NN cord-006870-f5w6fw6q 3487 8 - - HYPH cord-006870-f5w6fw6q 3487 9 based base VBN cord-006870-f5w6fw6q 3487 10 education education NN cord-006870-f5w6fw6q 3487 11 , , , cord-006870-f5w6fw6q 3487 12 in in IN cord-006870-f5w6fw6q 3487 13 - - HYPH cord-006870-f5w6fw6q 3487 14 service service NN cord-006870-f5w6fw6q 3487 15 , , , cord-006870-f5w6fw6q 3487 16 just just RB cord-006870-f5w6fw6q 3487 17 - - HYPH cord-006870-f5w6fw6q 3487 18 in in IN cord-006870-f5w6fw6q 3487 19 - - HYPH cord-006870-f5w6fw6q 3487 20 time time NN cord-006870-f5w6fw6q 3487 21 training training NN cord-006870-f5w6fw6q 3487 22 , , , cord-006870-f5w6fw6q 3487 23 and and CC cord-006870-f5w6fw6q 3487 24 booster booster NN cord-006870-f5w6fw6q 3487 25 education education NN cord-006870-f5w6fw6q 3487 26 was be VBD cord-006870-f5w6fw6q 3487 27 employed employ VBN cord-006870-f5w6fw6q 3487 28 to to TO cord-006870-f5w6fw6q 3487 29 identify identify VB cord-006870-f5w6fw6q 3487 30 process process NN cord-006870-f5w6fw6q 3487 31 , , , cord-006870-f5w6fw6q 3487 32 outcome outcome NN cord-006870-f5w6fw6q 3487 33 , , , cord-006870-f5w6fw6q 3487 34 and and CC cord-006870-f5w6fw6q 3487 35 improvement improvement NN cord-006870-f5w6fw6q 3487 36 opportunities opportunity NNS cord-006870-f5w6fw6q 3487 37 . . . cord-006870-f5w6fw6q 3488 1 After after IN cord-006870-f5w6fw6q 3488 2 rollout rollout NN cord-006870-f5w6fw6q 3488 3 of of IN cord-006870-f5w6fw6q 3488 4 the the DT cord-006870-f5w6fw6q 3488 5 new new JJ cord-006870-f5w6fw6q 3488 6 discharge discharge NN cord-006870-f5w6fw6q 3488 7 navigator navigator NN cord-006870-f5w6fw6q 3488 8 , , , cord-006870-f5w6fw6q 3488 9 90 90 CD cord-006870-f5w6fw6q 3488 10 % % NN cord-006870-f5w6fw6q 3488 11 of of IN cord-006870-f5w6fw6q 3488 12 all all DT cord-006870-f5w6fw6q 3488 13 patient patient NN cord-006870-f5w6fw6q 3488 14 - - HYPH cord-006870-f5w6fw6q 3488 15 facing face VBG cord-006870-f5w6fw6q 3488 16 staff staff NN cord-006870-f5w6fw6q 3488 17 successfully successfully RB cord-006870-f5w6fw6q 3488 18 completed complete VBD cord-006870-f5w6fw6q 3488 19 the the DT cord-006870-f5w6fw6q 3488 20 Inpatient Inpatient NNP cord-006870-f5w6fw6q 3488 21 Hospice Hospice NNP cord-006870-f5w6fw6q 3488 22 training training NN cord-006870-f5w6fw6q 3488 23 . . . cord-006870-f5w6fw6q 3489 1 Process process NN cord-006870-f5w6fw6q 3489 2 Improvements improvement NNS cord-006870-f5w6fw6q 3489 3 lead lead VBP cord-006870-f5w6fw6q 3489 4 to to TO cord-006870-f5w6fw6q 3489 5 increase increase NN cord-006870-f5w6fw6q 3489 6 in in IN cord-006870-f5w6fw6q 3489 7 Palliative Palliative NNP cord-006870-f5w6fw6q 3489 8 Care Care NNP cord-006870-f5w6fw6q 3489 9 consults consult VBZ cord-006870-f5w6fw6q 3489 10 by by IN cord-006870-f5w6fw6q 3489 11 500 500 CD cord-006870-f5w6fw6q 3489 12 % % NN cord-006870-f5w6fw6q 3489 13 ( ( -LRB- cord-006870-f5w6fw6q 3489 14 16 16 CD cord-006870-f5w6fw6q 3489 15 to to TO cord-006870-f5w6fw6q 3489 16 96 96 CD cord-006870-f5w6fw6q 3489 17 annually annually RB cord-006870-f5w6fw6q 3489 18 ) ) -RRB- cord-006870-f5w6fw6q 3489 19 and and CC cord-006870-f5w6fw6q 3489 20 Inpatient Inpatient NNP cord-006870-f5w6fw6q 3489 21 Hospice Hospice NNP cord-006870-f5w6fw6q 3489 22 discharges discharge VBZ cord-006870-f5w6fw6q 3489 23 up up IN cord-006870-f5w6fw6q 3489 24 to to TO cord-006870-f5w6fw6q 3489 25 30 30 CD cord-006870-f5w6fw6q 3489 26 % % NN cord-006870-f5w6fw6q 3489 27 ( ( -LRB- cord-006870-f5w6fw6q 3489 28 68 68 CD cord-006870-f5w6fw6q 3489 29 to to TO cord-006870-f5w6fw6q 3489 30 88 88 CD cord-006870-f5w6fw6q 3489 31 annually annually RB cord-006870-f5w6fw6q 3489 32 ) ) -RRB- cord-006870-f5w6fw6q 3489 33 . . . cord-006870-f5w6fw6q 3490 1 Furthermore furthermore RB cord-006870-f5w6fw6q 3490 2 , , , cord-006870-f5w6fw6q 3490 3 there there EX cord-006870-f5w6fw6q 3490 4 was be VBD cord-006870-f5w6fw6q 3490 5 a a DT cord-006870-f5w6fw6q 3490 6 statistically statistically RB cord-006870-f5w6fw6q 3490 7 significant significant JJ cord-006870-f5w6fw6q 3490 8 improvement improvement NN cord-006870-f5w6fw6q 3490 9 in in IN cord-006870-f5w6fw6q 3490 10 the the DT cord-006870-f5w6fw6q 3490 11 Vizient Vizient NNP cord-006870-f5w6fw6q 3490 12 Mortality Mortality NNP cord-006870-f5w6fw6q 3490 13 Index Index NNP cord-006870-f5w6fw6q 3490 14 R2 R2 NNP cord-006870-f5w6fw6q 3490 15 = = SYM cord-006870-f5w6fw6q 3490 16 .11 .11 NNP cord-006870-f5w6fw6q 3490 17 , , , cord-006870-f5w6fw6q 3490 18 F(1,51 F(1,51 NNP cord-006870-f5w6fw6q 3490 19 ) ) -RRB- cord-006870-f5w6fw6q 3490 20 = = NFP cord-006870-f5w6fw6q 3491 1 22.64 22.64 CD cord-006870-f5w6fw6q 3491 2 , , , cord-006870-f5w6fw6q 3492 1 p p LS cord-006870-f5w6fw6q 3492 2 < < XX cord-006870-f5w6fw6q 3492 3 .05 .05 NFP cord-006870-f5w6fw6q 3493 1 and and CC cord-006870-f5w6fw6q 3493 2 Length length NN cord-006870-f5w6fw6q 3493 3 of of IN cord-006870-f5w6fw6q 3493 4 Stay Stay NNP cord-006870-f5w6fw6q 3493 5 Index Index NNP cord-006870-f5w6fw6q 3493 6 R2 R2 NNP cord-006870-f5w6fw6q 3493 7 = = SYM cord-006870-f5w6fw6q 3493 8 .10 .10 NNP cord-006870-f5w6fw6q 3493 9 , , , cord-006870-f5w6fw6q 3493 10 F(1,51 F(1,51 NNP cord-006870-f5w6fw6q 3493 11 ) ) -RRB- cord-006870-f5w6fw6q 3493 12 = = SYM cord-006870-f5w6fw6q 3493 13 12.64 12.64 CD cord-006870-f5w6fw6q 3493 14 , , , cord-006870-f5w6fw6q 3493 15 p p NN cord-006870-f5w6fw6q 3493 16 < < XX cord-006870-f5w6fw6q 3493 17 .05 .05 NFP cord-006870-f5w6fw6q 3493 18 within within IN cord-006870-f5w6fw6q 3493 19 the the DT cord-006870-f5w6fw6q 3493 20 study study NN cord-006870-f5w6fw6q 3493 21 population population NN cord-006870-f5w6fw6q 3493 22 and and CC cord-006870-f5w6fw6q 3493 23 period period NN cord-006870-f5w6fw6q 3493 24 . . . cord-006870-f5w6fw6q 3494 1 Ability ability NN cord-006870-f5w6fw6q 3494 2 to to TO cord-006870-f5w6fw6q 3494 3 transfer transfer VB cord-006870-f5w6fw6q 3494 4 patients patient NNS cord-006870-f5w6fw6q 3494 5 to to IN cord-006870-f5w6fw6q 3494 6 inpatient inpatient JJ cord-006870-f5w6fw6q 3494 7 hospice hospice NN cord-006870-f5w6fw6q 3494 8 is be VBZ cord-006870-f5w6fw6q 3494 9 often often RB cord-006870-f5w6fw6q 3494 10 limited limit VBN cord-006870-f5w6fw6q 3494 11 and and CC cord-006870-f5w6fw6q 3494 12 complicated complicated JJ cord-006870-f5w6fw6q 3494 13 . . . cord-006870-f5w6fw6q 3495 1 This this DT cord-006870-f5w6fw6q 3495 2 study study NN cord-006870-f5w6fw6q 3495 3 shows show VBZ cord-006870-f5w6fw6q 3495 4 how how WRB cord-006870-f5w6fw6q 3495 5 employing employ VBG cord-006870-f5w6fw6q 3495 6 standard standard JJ cord-006870-f5w6fw6q 3495 7 Quality Quality NNP cord-006870-f5w6fw6q 3495 8 Improvement Improvement NNP cord-006870-f5w6fw6q 3495 9 as as RB cord-006870-f5w6fw6q 3495 10 well well RB cord-006870-f5w6fw6q 3495 11 as as IN cord-006870-f5w6fw6q 3495 12 Education education NN cord-006870-f5w6fw6q 3495 13 and and CC cord-006870-f5w6fw6q 3495 14 Implementation implementation NN cord-006870-f5w6fw6q 3495 15 methods method NNS cord-006870-f5w6fw6q 3495 16 can can MD cord-006870-f5w6fw6q 3495 17 result result VB cord-006870-f5w6fw6q 3495 18 in in IN cord-006870-f5w6fw6q 3495 19 improved improved JJ cord-006870-f5w6fw6q 3495 20 process process NN cord-006870-f5w6fw6q 3495 21 and and CC cord-006870-f5w6fw6q 3495 22 outcome outcome NN cord-006870-f5w6fw6q 3495 23 measures measure NNS cord-006870-f5w6fw6q 3495 24 with with IN cord-006870-f5w6fw6q 3495 25 sustainable sustainable JJ cord-006870-f5w6fw6q 3495 26 success success NN cord-006870-f5w6fw6q 3495 27 . . . cord-006870-f5w6fw6q 3496 1 Opportunities opportunity NNS cord-006870-f5w6fw6q 3496 2 remain remain VBP cord-006870-f5w6fw6q 3496 3 in in IN cord-006870-f5w6fw6q 3496 4 further further JJ cord-006870-f5w6fw6q 3496 5 analyzing analyze VBG cord-006870-f5w6fw6q 3496 6 and and CC cord-006870-f5w6fw6q 3496 7 optimizing optimize VBG cord-006870-f5w6fw6q 3496 8 ' ' '' cord-006870-f5w6fw6q 3496 9 Time time NN cord-006870-f5w6fw6q 3496 10 to to IN cord-006870-f5w6fw6q 3496 11 Palliative Palliative NNP cord-006870-f5w6fw6q 3496 12 Care Care NNP cord-006870-f5w6fw6q 3496 13 consult consult NN cord-006870-f5w6fw6q 3496 14 ' ' '' cord-006870-f5w6fw6q 3496 15 , , , cord-006870-f5w6fw6q 3496 16 ' ' '' cord-006870-f5w6fw6q 3496 17 Time time NN cord-006870-f5w6fw6q 3496 18 to to IN cord-006870-f5w6fw6q 3496 19 Admission admission NN cord-006870-f5w6fw6q 3496 20 to to IN cord-006870-f5w6fw6q 3496 21 Hospice Hospice NNP cord-006870-f5w6fw6q 3496 22 and and CC cord-006870-f5w6fw6q 3496 23 Withdrawal Withdrawal NNP cord-006870-f5w6fw6q 3496 24 of of IN cord-006870-f5w6fw6q 3496 25 Artificial Artificial NNP cord-006870-f5w6fw6q 3496 26 Support Support NNP cord-006870-f5w6fw6q 3496 27 ' ' '' cord-006870-f5w6fw6q 3496 28 . . . cord-006870-f5w6fw6q 3497 1 ARNP ARNP NNP cord-006870-f5w6fw6q 3497 2 and and CC cord-006870-f5w6fw6q 3497 3 PA PA NNP cord-006870-f5w6fw6q 3497 4 's 's POS cord-006870-f5w6fw6q 3497 5 are be VBP cord-006870-f5w6fw6q 3497 6 a a DT cord-006870-f5w6fw6q 3497 7 rapidly rapidly RB cord-006870-f5w6fw6q 3497 8 growing grow VBG cord-006870-f5w6fw6q 3497 9 part part NN cord-006870-f5w6fw6q 3497 10 of of IN cord-006870-f5w6fw6q 3497 11 the the DT cord-006870-f5w6fw6q 3497 12 critical critical JJ cord-006870-f5w6fw6q 3497 13 care care NN cord-006870-f5w6fw6q 3497 14 workforce workforce NN cord-006870-f5w6fw6q 3497 15 . . . cord-006870-f5w6fw6q 3498 1 Proper proper JJ cord-006870-f5w6fw6q 3498 2 selection selection NN cord-006870-f5w6fw6q 3498 3 among among IN cord-006870-f5w6fw6q 3498 4 a a DT cord-006870-f5w6fw6q 3498 5 pool pool NN cord-006870-f5w6fw6q 3498 6 of of IN cord-006870-f5w6fw6q 3498 7 APP app NN cord-006870-f5w6fw6q 3498 8 candidates candidate NNS cord-006870-f5w6fw6q 3498 9 for for IN cord-006870-f5w6fw6q 3498 10 the the DT cord-006870-f5w6fw6q 3498 11 job job NN cord-006870-f5w6fw6q 3498 12 is be VBZ cord-006870-f5w6fw6q 3498 13 necessary necessary JJ cord-006870-f5w6fw6q 3498 14 to to TO cord-006870-f5w6fw6q 3498 15 ensure ensure VB cord-006870-f5w6fw6q 3498 16 the the DT cord-006870-f5w6fw6q 3498 17 " " `` cord-006870-f5w6fw6q 3498 18 right right JJ cord-006870-f5w6fw6q 3498 19 fit fit NN cord-006870-f5w6fw6q 3498 20 " " '' cord-006870-f5w6fw6q 3498 21 and and CC cord-006870-f5w6fw6q 3498 22 optimize optimize VB cord-006870-f5w6fw6q 3498 23 patient patient JJ cord-006870-f5w6fw6q 3498 24 safety safety NN cord-006870-f5w6fw6q 3498 25 . . . cord-006870-f5w6fw6q 3499 1 Conventional conventional JJ cord-006870-f5w6fw6q 3499 2 interview interview NN cord-006870-f5w6fw6q 3499 3 techniques technique NNS cord-006870-f5w6fw6q 3499 4 may may MD cord-006870-f5w6fw6q 3499 5 not not RB cord-006870-f5w6fw6q 3499 6 be be VB cord-006870-f5w6fw6q 3499 7 adequate adequate JJ cord-006870-f5w6fw6q 3499 8 when when WRB cord-006870-f5w6fw6q 3499 9 selecting select VBG cord-006870-f5w6fw6q 3499 10 critical critical JJ cord-006870-f5w6fw6q 3499 11 care care NN cord-006870-f5w6fw6q 3499 12 APP app NN cord-006870-f5w6fw6q 3499 13 's 's POS cord-006870-f5w6fw6q 3499 14 . . . cord-006870-f5w6fw6q 3500 1 We -PRON- PRP cord-006870-f5w6fw6q 3500 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 3500 3 that that IN cord-006870-f5w6fw6q 3500 4 use use NN cord-006870-f5w6fw6q 3500 5 of of IN cord-006870-f5w6fw6q 3500 6 a a DT cord-006870-f5w6fw6q 3500 7 Simulation Simulation NNP cord-006870-f5w6fw6q 3500 8 Center Center NNP cord-006870-f5w6fw6q 3500 9 could could MD cord-006870-f5w6fw6q 3500 10 be be VB cord-006870-f5w6fw6q 3500 11 used use VBN cord-006870-f5w6fw6q 3500 12 to to TO cord-006870-f5w6fw6q 3500 13 help help VB cord-006870-f5w6fw6q 3500 14 select select VB cord-006870-f5w6fw6q 3500 15 APP app NN cord-006870-f5w6fw6q 3500 16 candidates candidate NNS cord-006870-f5w6fw6q 3500 17 based base VBN cord-006870-f5w6fw6q 3500 18 on on IN cord-006870-f5w6fw6q 3500 19 their -PRON- PRP$ cord-006870-f5w6fw6q 3500 20 critical critical JJ cord-006870-f5w6fw6q 3500 21 thinking thinking NN cord-006870-f5w6fw6q 3500 22 skills skill NNS cord-006870-f5w6fw6q 3500 23 in in IN cord-006870-f5w6fw6q 3500 24 conjunction conjunction NN cord-006870-f5w6fw6q 3500 25 with with IN cord-006870-f5w6fw6q 3500 26 contemporary contemporary JJ cord-006870-f5w6fw6q 3500 27 interviewing interviewing NN cord-006870-f5w6fw6q 3500 28 skills skill NNS cord-006870-f5w6fw6q 3500 29 . . . cord-006870-f5w6fw6q 3501 1 From from IN cord-006870-f5w6fw6q 3501 2 2010 2010 CD cord-006870-f5w6fw6q 3501 3 to to IN cord-006870-f5w6fw6q 3501 4 2013 2013 CD cord-006870-f5w6fw6q 3501 5 , , , cord-006870-f5w6fw6q 3501 6 we -PRON- PRP cord-006870-f5w6fw6q 3501 7 performed perform VBD cord-006870-f5w6fw6q 3501 8 conventional conventional JJ cord-006870-f5w6fw6q 3501 9 interviews interview NNS cord-006870-f5w6fw6q 3501 10 for for IN cord-006870-f5w6fw6q 3501 11 APP APP NNP cord-006870-f5w6fw6q 3501 12 's 's POS cord-006870-f5w6fw6q 3501 13 to to TO cord-006870-f5w6fw6q 3501 14 staff staff VB cord-006870-f5w6fw6q 3501 15 critical critical JJ cord-006870-f5w6fw6q 3501 16 care care NN cord-006870-f5w6fw6q 3501 17 and and CC cord-006870-f5w6fw6q 3501 18 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3501 19 care care NN cord-006870-f5w6fw6q 3501 20 patients patient NNS cord-006870-f5w6fw6q 3501 21 . . . cord-006870-f5w6fw6q 3502 1 In in IN cord-006870-f5w6fw6q 3502 2 2014 2014 CD cord-006870-f5w6fw6q 3502 3 we -PRON- PRP cord-006870-f5w6fw6q 3502 4 changed change VBD cord-006870-f5w6fw6q 3502 5 to to IN cord-006870-f5w6fw6q 3502 6 an an DT cord-006870-f5w6fw6q 3502 7 interview interview NN cord-006870-f5w6fw6q 3502 8 process process NN cord-006870-f5w6fw6q 3502 9 consisting consist VBG cord-006870-f5w6fw6q 3502 10 of of IN cord-006870-f5w6fw6q 3502 11 the the DT cord-006870-f5w6fw6q 3502 12 conventional conventional JJ cord-006870-f5w6fw6q 3502 13 interaction interaction NN cord-006870-f5w6fw6q 3502 14 with with IN cord-006870-f5w6fw6q 3502 15 the the DT cord-006870-f5w6fw6q 3502 16 interviewee interviewee NN cord-006870-f5w6fw6q 3502 17 followed follow VBN cord-006870-f5w6fw6q 3502 18 by by IN cord-006870-f5w6fw6q 3502 19 simulation simulation NN cord-006870-f5w6fw6q 3502 20 . . . cord-006870-f5w6fw6q 3503 1 After after IN cord-006870-f5w6fw6q 3503 2 narrowing narrow VBG cord-006870-f5w6fw6q 3503 3 down down RP cord-006870-f5w6fw6q 3503 4 the the DT cord-006870-f5w6fw6q 3503 5 initial initial JJ cord-006870-f5w6fw6q 3503 6 candidate candidate NN cord-006870-f5w6fw6q 3503 7 pool pool NN cord-006870-f5w6fw6q 3503 8 , , , cord-006870-f5w6fw6q 3503 9 each each DT cord-006870-f5w6fw6q 3503 10 was be VBD cord-006870-f5w6fw6q 3503 11 taken take VBN cord-006870-f5w6fw6q 3503 12 to to IN cord-006870-f5w6fw6q 3503 13 the the DT cord-006870-f5w6fw6q 3503 14 simulation simulation NN cord-006870-f5w6fw6q 3503 15 center center NN cord-006870-f5w6fw6q 3503 16 where where WRB cord-006870-f5w6fw6q 3503 17 they -PRON- PRP cord-006870-f5w6fw6q 3503 18 participated participate VBD cord-006870-f5w6fw6q 3503 19 in in IN cord-006870-f5w6fw6q 3503 20 a a DT cord-006870-f5w6fw6q 3503 21 simulation simulation NN cord-006870-f5w6fw6q 3503 22 of of IN cord-006870-f5w6fw6q 3503 23 a a DT cord-006870-f5w6fw6q 3503 24 decompensating decompensate VBG cord-006870-f5w6fw6q 3503 25 patient patient NN cord-006870-f5w6fw6q 3503 26 . . . cord-006870-f5w6fw6q 3504 1 Proctors proctor NNS cord-006870-f5w6fw6q 3504 2 were be VBD cord-006870-f5w6fw6q 3504 3 able able JJ cord-006870-f5w6fw6q 3504 4 to to TO cord-006870-f5w6fw6q 3504 5 view view VB cord-006870-f5w6fw6q 3504 6 the the DT cord-006870-f5w6fw6q 3504 7 simulation simulation NN cord-006870-f5w6fw6q 3504 8 in in IN cord-006870-f5w6fw6q 3504 9 a a DT cord-006870-f5w6fw6q 3504 10 separate separate JJ cord-006870-f5w6fw6q 3504 11 room room NN cord-006870-f5w6fw6q 3504 12 and and CC cord-006870-f5w6fw6q 3504 13 direct direct VB cord-006870-f5w6fw6q 3504 14 the the DT cord-006870-f5w6fw6q 3504 15 simulation simulation NN cord-006870-f5w6fw6q 3504 16 mannequin mannequin NN cord-006870-f5w6fw6q 3504 17 . . . cord-006870-f5w6fw6q 3505 1 During during IN cord-006870-f5w6fw6q 3505 2 this this DT cord-006870-f5w6fw6q 3505 3 time time NN cord-006870-f5w6fw6q 3505 4 proctors proctor NNS cord-006870-f5w6fw6q 3505 5 were be VBD cord-006870-f5w6fw6q 3505 6 able able JJ cord-006870-f5w6fw6q 3505 7 to to TO cord-006870-f5w6fw6q 3505 8 evaluate evaluate VB cord-006870-f5w6fw6q 3505 9 the the DT cord-006870-f5w6fw6q 3505 10 interviewee interviewee NN cord-006870-f5w6fw6q 3505 11 's 's POS cord-006870-f5w6fw6q 3505 12 patient patient JJ cord-006870-f5w6fw6q 3505 13 interaction interaction NN cord-006870-f5w6fw6q 3505 14 , , , cord-006870-f5w6fw6q 3505 15 assessment assessment NN cord-006870-f5w6fw6q 3505 16 and and CC cord-006870-f5w6fw6q 3505 17 interventions intervention NNS cord-006870-f5w6fw6q 3505 18 . . . cord-006870-f5w6fw6q 3506 1 An an DT cord-006870-f5w6fw6q 3506 2 evaluation evaluation NN cord-006870-f5w6fw6q 3506 3 tool tool NN cord-006870-f5w6fw6q 3506 4 was be VBD cord-006870-f5w6fw6q 3506 5 to to IN cord-006870-f5w6fw6q 3506 6 grade grade NN cord-006870-f5w6fw6q 3506 7 APP app NN cord-006870-f5w6fw6q 3506 8 candidates candidate NNS cord-006870-f5w6fw6q 3506 9 for for IN cord-006870-f5w6fw6q 3506 10 their -PRON- PRP$ cord-006870-f5w6fw6q 3506 11 decision decision NN cord-006870-f5w6fw6q 3506 12 making make VBG cord-006870-f5w6fw6q 3506 13 skills skill NNS cord-006870-f5w6fw6q 3506 14 , , , cord-006870-f5w6fw6q 3506 15 communication communication NN cord-006870-f5w6fw6q 3506 16 and and CC cord-006870-f5w6fw6q 3506 17 thought thought NN cord-006870-f5w6fw6q 3506 18 . . . cord-006870-f5w6fw6q 3507 1 From from IN cord-006870-f5w6fw6q 3507 2 2014 2014 CD cord-006870-f5w6fw6q 3507 3 to to IN cord-006870-f5w6fw6q 3507 4 2017 2017 CD cord-006870-f5w6fw6q 3507 5 , , , cord-006870-f5w6fw6q 3507 6 we -PRON- PRP cord-006870-f5w6fw6q 3507 7 screened screen VBD cord-006870-f5w6fw6q 3507 8 40 40 CD cord-006870-f5w6fw6q 3507 9 candidates candidate NNS cord-006870-f5w6fw6q 3507 10 before before IN cord-006870-f5w6fw6q 3507 11 selecting select VBG cord-006870-f5w6fw6q 3507 12 21 21 CD cord-006870-f5w6fw6q 3507 13 for for IN cord-006870-f5w6fw6q 3507 14 interviews interview NNS cord-006870-f5w6fw6q 3507 15 and and CC cord-006870-f5w6fw6q 3507 16 finally finally RB cord-006870-f5w6fw6q 3507 17 10 10 CD cord-006870-f5w6fw6q 3507 18 of of IN cord-006870-f5w6fw6q 3507 19 those those DT cord-006870-f5w6fw6q 3507 20 for for IN cord-006870-f5w6fw6q 3507 21 simulation simulation NN cord-006870-f5w6fw6q 3507 22 . . . cord-006870-f5w6fw6q 3508 1 Over over IN cord-006870-f5w6fw6q 3508 2 this this DT cord-006870-f5w6fw6q 3508 3 timeframe timeframe NN cord-006870-f5w6fw6q 3508 4 , , , cord-006870-f5w6fw6q 3508 5 our -PRON- PRP$ cord-006870-f5w6fw6q 3508 6 center center NN cord-006870-f5w6fw6q 3508 7 hired hire VBD cord-006870-f5w6fw6q 3508 8 6 6 CD cord-006870-f5w6fw6q 3508 9 APP app NN cord-006870-f5w6fw6q 3508 10 's 's POS cord-006870-f5w6fw6q 3508 11 . . . cord-006870-f5w6fw6q 3509 1 Comparing compare VBG cord-006870-f5w6fw6q 3509 2 the the DT cord-006870-f5w6fw6q 3509 3 ratio ratio NN cord-006870-f5w6fw6q 3509 4 of of IN cord-006870-f5w6fw6q 3509 5 screen screen NN cord-006870-f5w6fw6q 3509 6 applicants applicant NNS cord-006870-f5w6fw6q 3509 7 to to IN cord-006870-f5w6fw6q 3509 8 employment employment NN cord-006870-f5w6fw6q 3509 9 was be VBD cord-006870-f5w6fw6q 3509 10 6.6 6.6 CD cord-006870-f5w6fw6q 3509 11 and and CC cord-006870-f5w6fw6q 3509 12 ratio ratio NN cord-006870-f5w6fw6q 3509 13 of of IN cord-006870-f5w6fw6q 3509 14 interviewed interview VBN cord-006870-f5w6fw6q 3509 15 to to IN cord-006870-f5w6fw6q 3509 16 hired hire VBN cord-006870-f5w6fw6q 3509 17 candidates candidate NNS cord-006870-f5w6fw6q 3509 18 was be VBD cord-006870-f5w6fw6q 3509 19 3.5 3.5 CD cord-006870-f5w6fw6q 3509 20 . . . cord-006870-f5w6fw6q 3510 1 These these DT cord-006870-f5w6fw6q 3510 2 ratios ratio NNS cord-006870-f5w6fw6q 3510 3 show show VBP cord-006870-f5w6fw6q 3510 4 the the DT cord-006870-f5w6fw6q 3510 5 competitive competitive JJ cord-006870-f5w6fw6q 3510 6 process process NN cord-006870-f5w6fw6q 3510 7 and and CC cord-006870-f5w6fw6q 3510 8 potential potential JJ cord-006870-f5w6fw6q 3510 9 use use NN cord-006870-f5w6fw6q 3510 10 of of IN cord-006870-f5w6fw6q 3510 11 Simulation Simulation NNP cord-006870-f5w6fw6q 3510 12 in in IN cord-006870-f5w6fw6q 3510 13 selecting select VBG cord-006870-f5w6fw6q 3510 14 APPs app NNS cord-006870-f5w6fw6q 3510 15 . . . cord-006870-f5w6fw6q 3511 1 Compared compare VBN cord-006870-f5w6fw6q 3511 2 to to IN cord-006870-f5w6fw6q 3511 3 the the DT cord-006870-f5w6fw6q 3511 4 time time NN cord-006870-f5w6fw6q 3511 5 period period NN cord-006870-f5w6fw6q 3511 6 of of IN cord-006870-f5w6fw6q 3511 7 applicants applicant NNS cord-006870-f5w6fw6q 3511 8 prior prior RB cord-006870-f5w6fw6q 3511 9 to to IN cord-006870-f5w6fw6q 3511 10 Simulation Simulation NNP cord-006870-f5w6fw6q 3511 11 to to IN cord-006870-f5w6fw6q 3511 12 after after IN cord-006870-f5w6fw6q 3511 13 , , , cord-006870-f5w6fw6q 3511 14 retention retention NN cord-006870-f5w6fw6q 3511 15 went go VBD cord-006870-f5w6fw6q 3511 16 from from IN cord-006870-f5w6fw6q 3511 17 75 75 CD cord-006870-f5w6fw6q 3511 18 to to TO cord-006870-f5w6fw6q 3511 19 92 92 CD cord-006870-f5w6fw6q 3511 20 % % NN cord-006870-f5w6fw6q 3511 21 , , , cord-006870-f5w6fw6q 3511 22 and and CC cord-006870-f5w6fw6q 3511 23 disciplinary disciplinary JJ cord-006870-f5w6fw6q 3511 24 action action NN cord-006870-f5w6fw6q 3511 25 for for IN cord-006870-f5w6fw6q 3511 26 practice practice NN cord-006870-f5w6fw6q 3511 27 deficiencies deficiency NNS cord-006870-f5w6fw6q 3511 28 went go VBD cord-006870-f5w6fw6q 3511 29 from from IN cord-006870-f5w6fw6q 3511 30 16 16 CD cord-006870-f5w6fw6q 3511 31 % % NN cord-006870-f5w6fw6q 3511 32 to to IN cord-006870-f5w6fw6q 3511 33 0 0 CD cord-006870-f5w6fw6q 3511 34 % % NN cord-006870-f5w6fw6q 3511 35 . . . cord-006870-f5w6fw6q 3512 1 The the DT cord-006870-f5w6fw6q 3512 2 use use NN cord-006870-f5w6fw6q 3512 3 of of IN cord-006870-f5w6fw6q 3512 4 simulation simulation NN cord-006870-f5w6fw6q 3512 5 based base VBN cord-006870-f5w6fw6q 3512 6 interviews interview NNS cord-006870-f5w6fw6q 3512 7 for for IN cord-006870-f5w6fw6q 3512 8 critical critical JJ cord-006870-f5w6fw6q 3512 9 care care NN cord-006870-f5w6fw6q 3512 10 APP app NN cord-006870-f5w6fw6q 3512 11 's be VBZ cord-006870-f5w6fw6q 3512 12 in in IN cord-006870-f5w6fw6q 3512 13 our -PRON- PRP$ cord-006870-f5w6fw6q 3512 14 institution institution NN cord-006870-f5w6fw6q 3512 15 improved improve VBD cord-006870-f5w6fw6q 3512 16 retention retention NN cord-006870-f5w6fw6q 3512 17 and and CC cord-006870-f5w6fw6q 3512 18 decreased decrease VBD cord-006870-f5w6fw6q 3512 19 the the DT cord-006870-f5w6fw6q 3512 20 number number NN cord-006870-f5w6fw6q 3512 21 of of IN cord-006870-f5w6fw6q 3512 22 disciplinary disciplinary JJ cord-006870-f5w6fw6q 3512 23 actions action NNS cord-006870-f5w6fw6q 3512 24 compared compare VBN cord-006870-f5w6fw6q 3512 25 to to IN cord-006870-f5w6fw6q 3512 26 conventional conventional JJ cord-006870-f5w6fw6q 3512 27 interview interview NN cord-006870-f5w6fw6q 3512 28 methods method NNS cord-006870-f5w6fw6q 3512 29 . . . cord-006870-f5w6fw6q 3513 1 The the DT cord-006870-f5w6fw6q 3513 2 contraindications contraindication NNS cord-006870-f5w6fw6q 3513 3 for for IN cord-006870-f5w6fw6q 3513 4 lumbar lumbar NN cord-006870-f5w6fw6q 3513 5 puncture puncture NN cord-006870-f5w6fw6q 3513 6 ( ( -LRB- cord-006870-f5w6fw6q 3513 7 LP LP NNP cord-006870-f5w6fw6q 3513 8 ) ) -RRB- cord-006870-f5w6fw6q 3513 9 in in IN cord-006870-f5w6fw6q 3513 10 the the DT cord-006870-f5w6fw6q 3513 11 setting setting NN cord-006870-f5w6fw6q 3513 12 of of IN cord-006870-f5w6fw6q 3513 13 cerebral cerebral JJ cord-006870-f5w6fw6q 3513 14 mass mass JJ cord-006870-f5w6fw6q 3513 15 effect effect NN cord-006870-f5w6fw6q 3513 16 remain remain VBP cord-006870-f5w6fw6q 3513 17 debatable debatable JJ cord-006870-f5w6fw6q 3513 18 . . . cord-006870-f5w6fw6q 3514 1 Limited limited JJ cord-006870-f5w6fw6q 3514 2 retrospective retrospective JJ cord-006870-f5w6fw6q 3514 3 data datum NNS cord-006870-f5w6fw6q 3514 4 advocate advocate NN cord-006870-f5w6fw6q 3514 5 its -PRON- PRP$ cord-006870-f5w6fw6q 3514 6 potential potential JJ cord-006870-f5w6fw6q 3514 7 safety safety NN cord-006870-f5w6fw6q 3514 8 . . . cord-006870-f5w6fw6q 3515 1 Yet yet RB cord-006870-f5w6fw6q 3515 2 , , , cord-006870-f5w6fw6q 3515 3 high high JJ cord-006870-f5w6fw6q 3515 4 - - HYPH cord-006870-f5w6fw6q 3515 5 quality quality NN cord-006870-f5w6fw6q 3515 6 guidelines guideline NNS cord-006870-f5w6fw6q 3515 7 specifically specifically RB cord-006870-f5w6fw6q 3515 8 addressing address VBG cord-006870-f5w6fw6q 3515 9 this this DT cord-006870-f5w6fw6q 3515 10 topic topic NN cord-006870-f5w6fw6q 3515 11 are be VBP cord-006870-f5w6fw6q 3515 12 not not RB cord-006870-f5w6fw6q 3515 13 available available JJ cord-006870-f5w6fw6q 3515 14 . . . cord-006870-f5w6fw6q 3516 1 Specific specific JJ cord-006870-f5w6fw6q 3516 2 patient patient JJ cord-006870-f5w6fw6q 3516 3 populations population NNS cord-006870-f5w6fw6q 3516 4 ( ( -LRB- cord-006870-f5w6fw6q 3516 5 post post JJ cord-006870-f5w6fw6q 3516 6 - - JJ cord-006870-f5w6fw6q 3516 7 instrumentation instrumentation JJ cord-006870-f5w6fw6q 3516 8 & & CC cord-006870-f5w6fw6q 3516 9 immunosuppressed immunosuppressed JJ cord-006870-f5w6fw6q 3516 10 ) ) -RRB- cord-006870-f5w6fw6q 3516 11 may may MD cord-006870-f5w6fw6q 3516 12 benefit benefit VB cord-006870-f5w6fw6q 3516 13 from from IN cord-006870-f5w6fw6q 3516 14 CSF CSF NNP cord-006870-f5w6fw6q 3516 15 studies study NNS cord-006870-f5w6fw6q 3516 16 . . . cord-006870-f5w6fw6q 3517 1 We -PRON- PRP cord-006870-f5w6fw6q 3517 2 reviewed review VBD cord-006870-f5w6fw6q 3517 3 1072 1072 CD cord-006870-f5w6fw6q 3517 4 consecutive consecutive JJ cord-006870-f5w6fw6q 3517 5 patients patient NNS cord-006870-f5w6fw6q 3517 6 who who WP cord-006870-f5w6fw6q 3517 7 underwent undergo VBD cord-006870-f5w6fw6q 3517 8 LP LP NNP cord-006870-f5w6fw6q 3517 9 and and CC cord-006870-f5w6fw6q 3517 10 cerebral cerebral JJ cord-006870-f5w6fw6q 3517 11 imaging image VBG cord-006870-f5w6fw6q 3517 12 a a DT cord-006870-f5w6fw6q 3517 13 week week NN cord-006870-f5w6fw6q 3517 14 before before IN cord-006870-f5w6fw6q 3517 15 or or CC cord-006870-f5w6fw6q 3517 16 after after IN cord-006870-f5w6fw6q 3517 17 LP LP NNP cord-006870-f5w6fw6q 3517 18 from from IN cord-006870-f5w6fw6q 3517 19 2007 2007 CD cord-006870-f5w6fw6q 3517 20 - - SYM cord-006870-f5w6fw6q 3517 21 2014 2014 CD cord-006870-f5w6fw6q 3517 22 . . . cord-006870-f5w6fw6q 3518 1 All all DT cord-006870-f5w6fw6q 3518 2 individuals individual NNS cord-006870-f5w6fw6q 3518 3 with with IN cord-006870-f5w6fw6q 3518 4 evidence evidence NN cord-006870-f5w6fw6q 3518 5 of of IN cord-006870-f5w6fw6q 3518 6 brain brain NN cord-006870-f5w6fw6q 3518 7 herniation herniation NN cord-006870-f5w6fw6q 3518 8 , , , cord-006870-f5w6fw6q 3518 9 a a DT cord-006870-f5w6fw6q 3518 10 component component NN cord-006870-f5w6fw6q 3518 11 of of IN cord-006870-f5w6fw6q 3518 12 midline midline JJ cord-006870-f5w6fw6q 3518 13 shift shift NN cord-006870-f5w6fw6q 3518 14 , , , cord-006870-f5w6fw6q 3518 15 or or CC cord-006870-f5w6fw6q 3518 16 mass mass JJ cord-006870-f5w6fw6q 3518 17 effect effect NN cord-006870-f5w6fw6q 3518 18 were be VBD cord-006870-f5w6fw6q 3518 19 included include VBN cord-006870-f5w6fw6q 3518 20 . . . cord-006870-f5w6fw6q 3519 1 All all DT cord-006870-f5w6fw6q 3519 2 subjects subject NNS cord-006870-f5w6fw6q 3519 3 received receive VBD cord-006870-f5w6fw6q 3519 4 a a DT cord-006870-f5w6fw6q 3519 5 low low JJ cord-006870-f5w6fw6q 3519 6 volume volume NN cord-006870-f5w6fw6q 3519 7 LP lp NN cord-006870-f5w6fw6q 3519 8 ( ( -LRB- cord-006870-f5w6fw6q 3519 9 5 5 CD cord-006870-f5w6fw6q 3519 10 - - SYM cord-006870-f5w6fw6q 3519 11 10 10 CD cord-006870-f5w6fw6q 3519 12 cc cc CD cord-006870-f5w6fw6q 3519 13 of of IN cord-006870-f5w6fw6q 3519 14 CSF CSF NNP cord-006870-f5w6fw6q 3519 15 ) ) -RRB- cord-006870-f5w6fw6q 3519 16 . . . cord-006870-f5w6fw6q 3520 1 There there EX cord-006870-f5w6fw6q 3520 2 were be VBD cord-006870-f5w6fw6q 3520 3 132 132 CD cord-006870-f5w6fw6q 3520 4 patients patient NNS cord-006870-f5w6fw6q 3520 5 with with IN cord-006870-f5w6fw6q 3520 6 radiological radiological JJ cord-006870-f5w6fw6q 3520 7 increased increase VBN cord-006870-f5w6fw6q 3520 8 ICP ICP NNP cord-006870-f5w6fw6q 3520 9 . . . cord-006870-f5w6fw6q 3521 1 Midline midline JJ cord-006870-f5w6fw6q 3521 2 shift shift NN cord-006870-f5w6fw6q 3521 3 ( ( -LRB- cord-006870-f5w6fw6q 3521 4 average average JJ cord-006870-f5w6fw6q 3521 5 = = SYM cord-006870-f5w6fw6q 3521 6 4 4 CD cord-006870-f5w6fw6q 3521 7 mm mm NNP cord-006870-f5w6fw6q 3521 8 ) ) -RRB- cord-006870-f5w6fw6q 3521 9 was be VBD cord-006870-f5w6fw6q 3521 10 present present JJ cord-006870-f5w6fw6q 3521 11 in in IN cord-006870-f5w6fw6q 3521 12 39 39 CD cord-006870-f5w6fw6q 3521 13 patients patient NNS cord-006870-f5w6fw6q 3521 14 . . . cord-006870-f5w6fw6q 3522 1 We -PRON- PRP cord-006870-f5w6fw6q 3522 2 also also RB cord-006870-f5w6fw6q 3522 3 observed observe VBD cord-006870-f5w6fw6q 3522 4 herniation herniation NN cord-006870-f5w6fw6q 3522 5 : : : cord-006870-f5w6fw6q 3522 6 uncal uncal NNP cord-006870-f5w6fw6q 3522 7 ( ( -LRB- cord-006870-f5w6fw6q 3522 8 n=16 n=16 NNP cord-006870-f5w6fw6q 3522 9 ) ) -RRB- cord-006870-f5w6fw6q 3522 10 , , , cord-006870-f5w6fw6q 3522 11 subfalcine subfalcine NNP cord-006870-f5w6fw6q 3522 12 ( ( -LRB- cord-006870-f5w6fw6q 3522 13 n=15 n=15 NNP cord-006870-f5w6fw6q 3522 14 ) ) -RRB- cord-006870-f5w6fw6q 3522 15 , , , cord-006870-f5w6fw6q 3522 16 and and CC cord-006870-f5w6fw6q 3522 17 a a DT cord-006870-f5w6fw6q 3522 18 combination combination NN cord-006870-f5w6fw6q 3522 19 of of IN cord-006870-f5w6fw6q 3522 20 both both DT cord-006870-f5w6fw6q 3522 21 ( ( -LRB- cord-006870-f5w6fw6q 3522 22 n=10 n=10 NNP cord-006870-f5w6fw6q 3522 23 ) ) -RRB- cord-006870-f5w6fw6q 3522 24 , , , cord-006870-f5w6fw6q 3522 25 ventricular ventricular JJ cord-006870-f5w6fw6q 3522 26 effacement effacement NN cord-006870-f5w6fw6q 3522 27 ( ( -LRB- cord-006870-f5w6fw6q 3522 28 n=67 n=67 NN cord-006870-f5w6fw6q 3522 29 ) ) -RRB- cord-006870-f5w6fw6q 3522 30 and and CC cord-006870-f5w6fw6q 3522 31 cisternal cisternal JJ cord-006870-f5w6fw6q 3522 32 compression compression NN cord-006870-f5w6fw6q 3522 33 with with IN cord-006870-f5w6fw6q 3522 34 partial partial JJ cord-006870-f5w6fw6q 3522 35 occlusion occlusion NN cord-006870-f5w6fw6q 3522 36 : : : cord-006870-f5w6fw6q 3522 37 Quadrigeminal quadrigeminal JJ cord-006870-f5w6fw6q 3522 38 cistern cistern NN cord-006870-f5w6fw6q 3522 39 ( ( -LRB- cord-006870-f5w6fw6q 3522 40 n=3 n=3 NN cord-006870-f5w6fw6q 3522 41 ) ) -RRB- cord-006870-f5w6fw6q 3522 42 , , , cord-006870-f5w6fw6q 3522 43 cerebellar cerebellar JJ cord-006870-f5w6fw6q 3522 44 - - HYPH cord-006870-f5w6fw6q 3522 45 pontine pontine JJ cord-006870-f5w6fw6q 3522 46 - - HYPH cord-006870-f5w6fw6q 3522 47 angle angle NN cord-006870-f5w6fw6q 3522 48 cistern cistern NN cord-006870-f5w6fw6q 3522 49 ( ( -LRB- cord-006870-f5w6fw6q 3522 50 n= n= NNP cord-006870-f5w6fw6q 3522 51 14 14 CD cord-006870-f5w6fw6q 3522 52 ) ) -RRB- cord-006870-f5w6fw6q 3522 53 , , , cord-006870-f5w6fw6q 3522 54 ambient ambient JJ cord-006870-f5w6fw6q 3522 55 cistern cistern NN cord-006870-f5w6fw6q 3522 56 ( ( -LRB- cord-006870-f5w6fw6q 3522 57 n=24 n=24 NNP cord-006870-f5w6fw6q 3522 58 ) ) -RRB- cord-006870-f5w6fw6q 3522 59 , , , cord-006870-f5w6fw6q 3522 60 crural crural JJ cord-006870-f5w6fw6q 3522 61 cistern cistern NN cord-006870-f5w6fw6q 3522 62 ( ( -LRB- cord-006870-f5w6fw6q 3522 63 n=14 n=14 NNP cord-006870-f5w6fw6q 3522 64 ) ) -RRB- cord-006870-f5w6fw6q 3522 65 , , , cord-006870-f5w6fw6q 3522 66 prepontine prepontine NN cord-006870-f5w6fw6q 3522 67 cistern cistern NN cord-006870-f5w6fw6q 3522 68 ( ( -LRB- cord-006870-f5w6fw6q 3522 69 n=7 n=7 NNP cord-006870-f5w6fw6q 3522 70 ) ) -RRB- cord-006870-f5w6fw6q 3522 71 , , , cord-006870-f5w6fw6q 3522 72 suprasellar suprasellar NNP cord-006870-f5w6fw6q 3522 73 cistern cistern NNP cord-006870-f5w6fw6q 3522 74 ( ( -LRB- cord-006870-f5w6fw6q 3522 75 n=12 n=12 NNP cord-006870-f5w6fw6q 3522 76 ) ) -RRB- cord-006870-f5w6fw6q 3522 77 , , , cord-006870-f5w6fw6q 3522 78 basal basal NN cord-006870-f5w6fw6q 3522 79 cistern cistern NN cord-006870-f5w6fw6q 3522 80 ( ( -LRB- cord-006870-f5w6fw6q 3522 81 n= n= NNP cord-006870-f5w6fw6q 3522 82 2 2 CD cord-006870-f5w6fw6q 3522 83 ) ) -RRB- cord-006870-f5w6fw6q 3522 84 , , , cord-006870-f5w6fw6q 3522 85 suprachiasmatic suprachiasmatic NN cord-006870-f5w6fw6q 3522 86 cistern cistern NN cord-006870-f5w6fw6q 3522 87 ( ( -LRB- cord-006870-f5w6fw6q 3522 88 n= n= NNP cord-006870-f5w6fw6q 3522 89 4 4 CD cord-006870-f5w6fw6q 3522 90 ) ) -RRB- cord-006870-f5w6fw6q 3522 91 , , , cord-006870-f5w6fw6q 3522 92 cisterna cisterna NNP cord-006870-f5w6fw6q 3522 93 magna magna NNP cord-006870-f5w6fw6q 3522 94 ( ( -LRB- cord-006870-f5w6fw6q 3522 95 n=3 n=3 NNP cord-006870-f5w6fw6q 3522 96 ) ) -RRB- cord-006870-f5w6fw6q 3522 97 , , , cord-006870-f5w6fw6q 3522 98 interpeduncular interpeduncular NNP cord-006870-f5w6fw6q 3522 99 cistern cistern NN cord-006870-f5w6fw6q 3522 100 ( ( -LRB- cord-006870-f5w6fw6q 3522 101 n=3 n=3 NN cord-006870-f5w6fw6q 3522 102 ) ) -RRB- cord-006870-f5w6fw6q 3522 103 , , , cord-006870-f5w6fw6q 3522 104 medullary medullary JJ cord-006870-f5w6fw6q 3522 105 cistern cistern NN cord-006870-f5w6fw6q 3522 106 ( ( -LRB- cord-006870-f5w6fw6q 3522 107 n=4 n=4 NNP cord-006870-f5w6fw6q 3522 108 ) ) -RRB- cord-006870-f5w6fw6q 3522 109 . . . cord-006870-f5w6fw6q 3523 1 All all DT cord-006870-f5w6fw6q 3523 2 patients patient NNS cord-006870-f5w6fw6q 3523 3 tolerated tolerate VBD cord-006870-f5w6fw6q 3523 4 the the DT cord-006870-f5w6fw6q 3523 5 LP LP NNP cord-006870-f5w6fw6q 3523 6 without without IN cord-006870-f5w6fw6q 3523 7 complications complication NNS cord-006870-f5w6fw6q 3523 8 . . . cord-006870-f5w6fw6q 3524 1 Most Most JJS cord-006870-f5w6fw6q 3524 2 survived survive VBD cord-006870-f5w6fw6q 3524 3 a a DT cord-006870-f5w6fw6q 3524 4 week week NN cord-006870-f5w6fw6q 3524 5 after after IN cord-006870-f5w6fw6q 3524 6 the the DT cord-006870-f5w6fw6q 3524 7 procedure procedure NN cord-006870-f5w6fw6q 3524 8 ( ( -LRB- cord-006870-f5w6fw6q 3524 9 n=128 n=128 UH cord-006870-f5w6fw6q 3524 10 , , , cord-006870-f5w6fw6q 3524 11 97 97 CD cord-006870-f5w6fw6q 3524 12 % % NN cord-006870-f5w6fw6q 3524 13 ) ) -RRB- cord-006870-f5w6fw6q 3524 14 . . . cord-006870-f5w6fw6q 3525 1 Notably notably RB cord-006870-f5w6fw6q 3525 2 , , , cord-006870-f5w6fw6q 3525 3 four four CD cord-006870-f5w6fw6q 3525 4 individuals individual NNS cord-006870-f5w6fw6q 3525 5 deteriorated deteriorate VBD cord-006870-f5w6fw6q 3525 6 for for IN cord-006870-f5w6fw6q 3525 7 reasons reason NNS cord-006870-f5w6fw6q 3525 8 unrelated unrelated JJ cord-006870-f5w6fw6q 3525 9 to to IN cord-006870-f5w6fw6q 3525 10 the the DT cord-006870-f5w6fw6q 3525 11 LP LP NNP cord-006870-f5w6fw6q 3525 12 and and CC cord-006870-f5w6fw6q 3525 13 expired expire VBD cord-006870-f5w6fw6q 3525 14 within within IN cord-006870-f5w6fw6q 3525 15 a a DT cord-006870-f5w6fw6q 3525 16 week week NN cord-006870-f5w6fw6q 3525 17 because because IN cord-006870-f5w6fw6q 3525 18 of of IN cord-006870-f5w6fw6q 3525 19 withdrawal withdrawal NN cord-006870-f5w6fw6q 3525 20 of of IN cord-006870-f5w6fw6q 3525 21 care care NN cord-006870-f5w6fw6q 3525 22 . . . cord-006870-f5w6fw6q 3526 1 As as IN cord-006870-f5w6fw6q 3526 2 brain brain NN cord-006870-f5w6fw6q 3526 3 compliance compliance NN cord-006870-f5w6fw6q 3526 4 can can MD cord-006870-f5w6fw6q 3526 5 not not RB cord-006870-f5w6fw6q 3526 6 yet yet RB cord-006870-f5w6fw6q 3526 7 be be VB cord-006870-f5w6fw6q 3526 8 accurately accurately RB cord-006870-f5w6fw6q 3526 9 determined determine VBN cord-006870-f5w6fw6q 3526 10 radiologically radiologically RB cord-006870-f5w6fw6q 3526 11 , , , cord-006870-f5w6fw6q 3526 12 we -PRON- PRP cord-006870-f5w6fw6q 3526 13 believe believe VBP cord-006870-f5w6fw6q 3526 14 anatomical anatomical JJ cord-006870-f5w6fw6q 3526 15 involvement involvement NN cord-006870-f5w6fw6q 3526 16 should should MD cord-006870-f5w6fw6q 3526 17 drive drive VB cord-006870-f5w6fw6q 3526 18 decision decision NN cord-006870-f5w6fw6q 3526 19 - - HYPH cord-006870-f5w6fw6q 3526 20 making make VBG cord-006870-f5w6fw6q 3526 21 regarding regard VBG cord-006870-f5w6fw6q 3526 22 LP LP NNP cord-006870-f5w6fw6q 3526 23 safety safety NN cord-006870-f5w6fw6q 3526 24 . . . cord-006870-f5w6fw6q 3527 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3527 2 data datum NNS cord-006870-f5w6fw6q 3527 3 suggest suggest VBP cord-006870-f5w6fw6q 3527 4 that that IN cord-006870-f5w6fw6q 3527 5 a a DT cord-006870-f5w6fw6q 3527 6 low low JJ cord-006870-f5w6fw6q 3527 7 volume volume NN cord-006870-f5w6fw6q 3527 8 LP lp NN cord-006870-f5w6fw6q 3527 9 ( ( -LRB- cord-006870-f5w6fw6q 3527 10 5 5 CD cord-006870-f5w6fw6q 3527 11 - - SYM cord-006870-f5w6fw6q 3527 12 10 10 CD cord-006870-f5w6fw6q 3527 13 cc cc NN cord-006870-f5w6fw6q 3527 14 ) ) -RRB- cord-006870-f5w6fw6q 3527 15 might may MD cord-006870-f5w6fw6q 3527 16 be be VB cord-006870-f5w6fw6q 3527 17 safe safe JJ cord-006870-f5w6fw6q 3527 18 in in IN cord-006870-f5w6fw6q 3527 19 individuals individual NNS cord-006870-f5w6fw6q 3527 20 with with IN cord-006870-f5w6fw6q 3527 21 subfalcine subfalcine NNP cord-006870-f5w6fw6q 3527 22 herniation herniation NNP cord-006870-f5w6fw6q 3527 23 , , , cord-006870-f5w6fw6q 3527 24 midline midline JJ cord-006870-f5w6fw6q 3527 25 mass mass NN cord-006870-f5w6fw6q 3527 26 effect effect NN cord-006870-f5w6fw6q 3527 27 < < XX cord-006870-f5w6fw6q 3527 28 4 4 CD cord-006870-f5w6fw6q 3527 29 mm mm NN cord-006870-f5w6fw6q 3527 30 at at IN cord-006870-f5w6fw6q 3527 31 foramen foramen NN cord-006870-f5w6fw6q 3527 32 of of IN cord-006870-f5w6fw6q 3527 33 Monro Monro NNP cord-006870-f5w6fw6q 3527 34 level level NN cord-006870-f5w6fw6q 3527 35 , , , cord-006870-f5w6fw6q 3527 36 and and CC cord-006870-f5w6fw6q 3527 37 partial partial JJ cord-006870-f5w6fw6q 3527 38 cisternal cisternal JJ cord-006870-f5w6fw6q 3527 39 effacement effacement NN cord-006870-f5w6fw6q 3527 40 . . . cord-006870-f5w6fw6q 3528 1 We -PRON- PRP cord-006870-f5w6fw6q 3528 2 believe believe VBP cord-006870-f5w6fw6q 3528 3 that that IN cord-006870-f5w6fw6q 3528 4 while while IN cord-006870-f5w6fw6q 3528 5 LPs lp NNS cord-006870-f5w6fw6q 3528 6 might may MD cord-006870-f5w6fw6q 3528 7 be be VB cord-006870-f5w6fw6q 3528 8 safer safe JJR cord-006870-f5w6fw6q 3528 9 in in IN cord-006870-f5w6fw6q 3528 10 patients patient NNS cord-006870-f5w6fw6q 3528 11 with with IN cord-006870-f5w6fw6q 3528 12 supratentorial supratentorial JJ cord-006870-f5w6fw6q 3528 13 mass mass NN cord-006870-f5w6fw6q 3528 14 effect effect NN cord-006870-f5w6fw6q 3528 15 , , , cord-006870-f5w6fw6q 3528 16 individuals individual NNS cord-006870-f5w6fw6q 3528 17 with with IN cord-006870-f5w6fw6q 3528 18 posterior posterior JJ cord-006870-f5w6fw6q 3528 19 fossa fossa NN cord-006870-f5w6fw6q 3528 20 involvement involvement NN cord-006870-f5w6fw6q 3528 21 may may MD cord-006870-f5w6fw6q 3528 22 tolerate tolerate VB cord-006870-f5w6fw6q 3528 23 it -PRON- PRP cord-006870-f5w6fw6q 3528 24 as as RB cord-006870-f5w6fw6q 3528 25 well well RB cord-006870-f5w6fw6q 3528 26 . . . cord-006870-f5w6fw6q 3529 1 These these DT cord-006870-f5w6fw6q 3529 2 promising promising JJ cord-006870-f5w6fw6q 3529 3 findings finding NNS cord-006870-f5w6fw6q 3529 4 need need VBP cord-006870-f5w6fw6q 3529 5 further further JJ cord-006870-f5w6fw6q 3529 6 verification verification NN cord-006870-f5w6fw6q 3529 7 in in IN cord-006870-f5w6fw6q 3529 8 larger large JJR cord-006870-f5w6fw6q 3529 9 sample sample NN cord-006870-f5w6fw6q 3529 10 populations population NNS cord-006870-f5w6fw6q 3529 11 . . . cord-006870-f5w6fw6q 3530 1 The the DT cord-006870-f5w6fw6q 3530 2 importance importance NN cord-006870-f5w6fw6q 3530 3 of of IN cord-006870-f5w6fw6q 3530 4 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3530 5 care care NN cord-006870-f5w6fw6q 3530 6 has have VBZ cord-006870-f5w6fw6q 3530 7 recently recently RB cord-006870-f5w6fw6q 3530 8 been be VBN cord-006870-f5w6fw6q 3530 9 recognized recognize VBN cord-006870-f5w6fw6q 3530 10 in in IN cord-006870-f5w6fw6q 3530 11 Japan Japan NNP cord-006870-f5w6fw6q 3530 12 . . . cord-006870-f5w6fw6q 3531 1 However however RB cord-006870-f5w6fw6q 3531 2 , , , cord-006870-f5w6fw6q 3531 3 to to IN cord-006870-f5w6fw6q 3531 4 date date NN cord-006870-f5w6fw6q 3531 5 , , , cord-006870-f5w6fw6q 3531 6 there there EX cord-006870-f5w6fw6q 3531 7 has have VBZ cord-006870-f5w6fw6q 3531 8 been be VBN cord-006870-f5w6fw6q 3531 9 no no DT cord-006870-f5w6fw6q 3531 10 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3531 11 care care NN cord-006870-f5w6fw6q 3531 12 training training NN cord-006870-f5w6fw6q 3531 13 program program NN cord-006870-f5w6fw6q 3531 14 . . . cord-006870-f5w6fw6q 3532 1 We -PRON- PRP cord-006870-f5w6fw6q 3532 2 developed develop VBD cord-006870-f5w6fw6q 3532 3 the the DT cord-006870-f5w6fw6q 3532 4 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3532 5 Care Care NNP cord-006870-f5w6fw6q 3532 6 Hands Hands NNPS cord-006870-f5w6fw6q 3532 7 - - HYPH cord-006870-f5w6fw6q 3532 8 on on IN cord-006870-f5w6fw6q 3532 9 Seminar Seminar NNP cord-006870-f5w6fw6q 3532 10 as as IN cord-006870-f5w6fw6q 3532 11 a a DT cord-006870-f5w6fw6q 3532 12 proposed propose VBN cord-006870-f5w6fw6q 3532 13 training training NN cord-006870-f5w6fw6q 3532 14 module module NN cord-006870-f5w6fw6q 3532 15 , , , cord-006870-f5w6fw6q 3532 16 and and CC cord-006870-f5w6fw6q 3532 17 here here RB cord-006870-f5w6fw6q 3532 18 we -PRON- PRP cord-006870-f5w6fw6q 3532 19 report report VBP cord-006870-f5w6fw6q 3532 20 the the DT cord-006870-f5w6fw6q 3532 21 satisfaction satisfaction NN cord-006870-f5w6fw6q 3532 22 of of IN cord-006870-f5w6fw6q 3532 23 participants participant NNS cord-006870-f5w6fw6q 3532 24 . . . cord-006870-f5w6fw6q 3533 1 We -PRON- PRP cord-006870-f5w6fw6q 3533 2 prepared prepare VBD cord-006870-f5w6fw6q 3533 3 a a DT cord-006870-f5w6fw6q 3533 4 post post JJ cord-006870-f5w6fw6q 3533 5 - - JJ cord-006870-f5w6fw6q 3533 6 course course JJ cord-006870-f5w6fw6q 3533 7 questionnaire questionnaire NN cord-006870-f5w6fw6q 3533 8 about about IN cord-006870-f5w6fw6q 3533 9 participants participant NNS cord-006870-f5w6fw6q 3533 10 ' ' POS cord-006870-f5w6fw6q 3533 11 degree degree NN cord-006870-f5w6fw6q 3533 12 of of IN cord-006870-f5w6fw6q 3533 13 satisfaction satisfaction NN cord-006870-f5w6fw6q 3533 14 . . . cord-006870-f5w6fw6q 3534 1 The the DT cord-006870-f5w6fw6q 3534 2 main main JJ cord-006870-f5w6fw6q 3534 3 concept concept NN cord-006870-f5w6fw6q 3534 4 of of IN cord-006870-f5w6fw6q 3534 5 our -PRON- PRP$ cord-006870-f5w6fw6q 3534 6 seminar seminar NN cord-006870-f5w6fw6q 3534 7 was be VBD cord-006870-f5w6fw6q 3534 8 " " `` cord-006870-f5w6fw6q 3534 9 how how WRB cord-006870-f5w6fw6q 3534 10 to to TO cord-006870-f5w6fw6q 3534 11 maintain maintain VB cord-006870-f5w6fw6q 3534 12 cerebral cerebral JJ cord-006870-f5w6fw6q 3534 13 oxygen oxygen NN cord-006870-f5w6fw6q 3534 14 demand demand NN cord-006870-f5w6fw6q 3534 15 and and CC cord-006870-f5w6fw6q 3534 16 supply supply NN cord-006870-f5w6fw6q 3534 17 balance balance NN cord-006870-f5w6fw6q 3534 18 . . . cord-006870-f5w6fw6q 3534 19 " " '' cord-006870-f5w6fw6q 3535 1 Beginning begin VBG cord-006870-f5w6fw6q 3535 2 with with IN cord-006870-f5w6fw6q 3535 3 a a DT cord-006870-f5w6fw6q 3535 4 short short JJ cord-006870-f5w6fw6q 3535 5 lecture lecture NN cord-006870-f5w6fw6q 3535 6 about about IN cord-006870-f5w6fw6q 3535 7 this this DT cord-006870-f5w6fw6q 3535 8 concept concept NN cord-006870-f5w6fw6q 3535 9 , , , cord-006870-f5w6fw6q 3535 10 participants participant NNS cord-006870-f5w6fw6q 3535 11 joined join VBD cord-006870-f5w6fw6q 3535 12 four four CD cord-006870-f5w6fw6q 3535 13 hands hand NNS cord-006870-f5w6fw6q 3535 14 - - HYPH cord-006870-f5w6fw6q 3535 15 on on RP cord-006870-f5w6fw6q 3535 16 scenarios scenario NNS cord-006870-f5w6fw6q 3535 17 : : : cord-006870-f5w6fw6q 3535 18 post post JJ cord-006870-f5w6fw6q 3535 19 - - JJ cord-006870-f5w6fw6q 3535 20 cardiac cardiac JJ cord-006870-f5w6fw6q 3535 21 arrest arrest NN cord-006870-f5w6fw6q 3535 22 syndrome syndrome NN cord-006870-f5w6fw6q 3535 23 ( ( -LRB- cord-006870-f5w6fw6q 3535 24 PCAS PCAS NNP cord-006870-f5w6fw6q 3535 25 ) ) -RRB- cord-006870-f5w6fw6q 3535 26 , , , cord-006870-f5w6fw6q 3535 27 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3535 28 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3535 29 ( ( -LRB- cord-006870-f5w6fw6q 3535 30 SAH SAH NNP cord-006870-f5w6fw6q 3535 31 ) ) -RRB- cord-006870-f5w6fw6q 3535 32 , , , cord-006870-f5w6fw6q 3535 33 traumatic traumatic JJ cord-006870-f5w6fw6q 3535 34 brain brain NN cord-006870-f5w6fw6q 3535 35 injury injury NN cord-006870-f5w6fw6q 3535 36 ( ( -LRB- cord-006870-f5w6fw6q 3535 37 TBI TBI NNP cord-006870-f5w6fw6q 3535 38 ) ) -RRB- cord-006870-f5w6fw6q 3535 39 , , , cord-006870-f5w6fw6q 3535 40 and and CC cord-006870-f5w6fw6q 3535 41 states state NNS cord-006870-f5w6fw6q 3535 42 epilepticus epilepticus NN cord-006870-f5w6fw6q 3535 43 ( ( -LRB- cord-006870-f5w6fw6q 3535 44 SE SE NNP cord-006870-f5w6fw6q 3535 45 ) ) -RRB- cord-006870-f5w6fw6q 3535 46 . . . cord-006870-f5w6fw6q 3536 1 In in IN cord-006870-f5w6fw6q 3536 2 the the DT cord-006870-f5w6fw6q 3536 3 PCAS PCAS NNP cord-006870-f5w6fw6q 3536 4 scenario scenario NN cord-006870-f5w6fw6q 3536 5 , , , cord-006870-f5w6fw6q 3536 6 participants participant NNS cord-006870-f5w6fw6q 3536 7 learned learn VBD cord-006870-f5w6fw6q 3536 8 how how WRB cord-006870-f5w6fw6q 3536 9 to to IN cord-006870-f5w6fw6q 3536 10 trouble trouble NN cord-006870-f5w6fw6q 3536 11 shoot shoot VB cord-006870-f5w6fw6q 3536 12 regarding regard VBG cord-006870-f5w6fw6q 3536 13 targeted target VBN cord-006870-f5w6fw6q 3536 14 temperature temperature NN cord-006870-f5w6fw6q 3536 15 management management NN cord-006870-f5w6fw6q 3536 16 , , , cord-006870-f5w6fw6q 3536 17 especially especially RB cord-006870-f5w6fw6q 3536 18 in in IN cord-006870-f5w6fw6q 3536 19 regard regard NN cord-006870-f5w6fw6q 3536 20 to to IN cord-006870-f5w6fw6q 3536 21 the the DT cord-006870-f5w6fw6q 3536 22 management management NN cord-006870-f5w6fw6q 3536 23 of of IN cord-006870-f5w6fw6q 3536 24 shivering shiver VBG cord-006870-f5w6fw6q 3536 25 . . . cord-006870-f5w6fw6q 3537 1 In in IN cord-006870-f5w6fw6q 3537 2 the the DT cord-006870-f5w6fw6q 3537 3 SAH SAH NNP cord-006870-f5w6fw6q 3537 4 scenario scenario NN cord-006870-f5w6fw6q 3537 5 , , , cord-006870-f5w6fw6q 3537 6 they -PRON- PRP cord-006870-f5w6fw6q 3537 7 learned learn VBD cord-006870-f5w6fw6q 3537 8 about about IN cord-006870-f5w6fw6q 3537 9 perioperative perioperative JJ cord-006870-f5w6fw6q 3537 10 management management NN cord-006870-f5w6fw6q 3537 11 , , , cord-006870-f5w6fw6q 3537 12 including include VBG cord-006870-f5w6fw6q 3537 13 delayed delay VBN cord-006870-f5w6fw6q 3537 14 cerebral cerebral JJ cord-006870-f5w6fw6q 3537 15 ischemia ischemia NN cord-006870-f5w6fw6q 3537 16 . . . cord-006870-f5w6fw6q 3538 1 In in IN cord-006870-f5w6fw6q 3538 2 the the DT cord-006870-f5w6fw6q 3538 3 TBI TBI NNP cord-006870-f5w6fw6q 3538 4 scenario scenario NN cord-006870-f5w6fw6q 3538 5 , , , cord-006870-f5w6fw6q 3538 6 starting start VBG cord-006870-f5w6fw6q 3538 7 with with IN cord-006870-f5w6fw6q 3538 8 actual actual JJ cord-006870-f5w6fw6q 3538 9 insertion insertion NN cord-006870-f5w6fw6q 3538 10 of of IN cord-006870-f5w6fw6q 3538 11 an an DT cord-006870-f5w6fw6q 3538 12 intracranial intracranial JJ cord-006870-f5w6fw6q 3538 13 pressure pressure NN cord-006870-f5w6fw6q 3538 14 ( ( -LRB- cord-006870-f5w6fw6q 3538 15 ICP ICP NNP cord-006870-f5w6fw6q 3538 16 ) ) -RRB- cord-006870-f5w6fw6q 3538 17 monitor monitor VBP cord-006870-f5w6fw6q 3538 18 in in IN cord-006870-f5w6fw6q 3538 19 the the DT cord-006870-f5w6fw6q 3538 20 simulator simulator NN cord-006870-f5w6fw6q 3538 21 , , , cord-006870-f5w6fw6q 3538 22 they -PRON- PRP cord-006870-f5w6fw6q 3538 23 learned learn VBD cord-006870-f5w6fw6q 3538 24 about about IN cord-006870-f5w6fw6q 3538 25 ICP ICP NNP cord-006870-f5w6fw6q 3538 26 management management NN cord-006870-f5w6fw6q 3538 27 through through IN cord-006870-f5w6fw6q 3538 28 a a DT cord-006870-f5w6fw6q 3538 29 scenario scenario NN cord-006870-f5w6fw6q 3538 30 - - HYPH cord-006870-f5w6fw6q 3538 31 based base VBN cord-006870-f5w6fw6q 3538 32 simulation simulation NN cord-006870-f5w6fw6q 3538 33 . . . cord-006870-f5w6fw6q 3539 1 In in IN cord-006870-f5w6fw6q 3539 2 the the DT cord-006870-f5w6fw6q 3539 3 SE SE NNP cord-006870-f5w6fw6q 3539 4 scenario scenario NN cord-006870-f5w6fw6q 3539 5 , , , cord-006870-f5w6fw6q 3539 6 they -PRON- PRP cord-006870-f5w6fw6q 3539 7 learned learn VBD cord-006870-f5w6fw6q 3539 8 about about IN cord-006870-f5w6fw6q 3539 9 SE SE NNP cord-006870-f5w6fw6q 3539 10 management management NN cord-006870-f5w6fw6q 3539 11 , , , cord-006870-f5w6fw6q 3539 12 with with IN cord-006870-f5w6fw6q 3539 13 actual actual JJ cord-006870-f5w6fw6q 3539 14 continuous continuous JJ cord-006870-f5w6fw6q 3539 15 electroencephalogram electroencephalogram NN cord-006870-f5w6fw6q 3539 16 monitoring monitoring NN cord-006870-f5w6fw6q 3539 17 . . . cord-006870-f5w6fw6q 3540 1 This this DT cord-006870-f5w6fw6q 3540 2 seminar seminar NN cord-006870-f5w6fw6q 3540 3 was be VBD cord-006870-f5w6fw6q 3540 4 held hold VBN cord-006870-f5w6fw6q 3540 5 twice twice RB cord-006870-f5w6fw6q 3540 6 in in IN cord-006870-f5w6fw6q 3540 7 2017 2017 CD cord-006870-f5w6fw6q 3540 8 . . . cord-006870-f5w6fw6q 3541 1 Most Most JJS cord-006870-f5w6fw6q 3541 2 participants participant NNS cord-006870-f5w6fw6q 3541 3 were be VBD cord-006870-f5w6fw6q 3541 4 middle middle JJ cord-006870-f5w6fw6q 3541 5 - - HYPH cord-006870-f5w6fw6q 3541 6 aged aged JJ cord-006870-f5w6fw6q 3541 7 intensivists intensivist NNS cord-006870-f5w6fw6q 3541 8 ; ; : cord-006870-f5w6fw6q 3541 9 11 11 CD cord-006870-f5w6fw6q 3541 10 % % NN cord-006870-f5w6fw6q 3541 11 were be VBD cord-006870-f5w6fw6q 3541 12 in in IN cord-006870-f5w6fw6q 3541 13 their -PRON- PRP$ cord-006870-f5w6fw6q 3541 14 twenties twenty NNS cord-006870-f5w6fw6q 3541 15 ( ( -LRB- cord-006870-f5w6fw6q 3541 16 6/54 6/54 CD cord-006870-f5w6fw6q 3541 17 ) ) -RRB- cord-006870-f5w6fw6q 3541 18 , , , cord-006870-f5w6fw6q 3541 19 64.8 64.8 CD cord-006870-f5w6fw6q 3541 20 % % NN cord-006870-f5w6fw6q 3541 21 were be VBD cord-006870-f5w6fw6q 3541 22 in in IN cord-006870-f5w6fw6q 3541 23 their -PRON- PRP$ cord-006870-f5w6fw6q 3541 24 thirties thirty NNS cord-006870-f5w6fw6q 3541 25 ( ( -LRB- cord-006870-f5w6fw6q 3541 26 35/54 35/54 CD cord-006870-f5w6fw6q 3541 27 ) ) -RRB- cord-006870-f5w6fw6q 3541 28 , , , cord-006870-f5w6fw6q 3541 29 18.5 18.5 CD cord-006870-f5w6fw6q 3541 30 % % NN cord-006870-f5w6fw6q 3541 31 were be VBD cord-006870-f5w6fw6q 3541 32 in in IN cord-006870-f5w6fw6q 3541 33 their -PRON- PRP$ cord-006870-f5w6fw6q 3541 34 forties forty NNS cord-006870-f5w6fw6q 3541 35 ( ( -LRB- cord-006870-f5w6fw6q 3541 36 10/54 10/54 CD cord-006870-f5w6fw6q 3541 37 ) ) -RRB- cord-006870-f5w6fw6q 3541 38 , , , cord-006870-f5w6fw6q 3541 39 and and CC cord-006870-f5w6fw6q 3541 40 5.6 5.6 CD cord-006870-f5w6fw6q 3541 41 % % NN cord-006870-f5w6fw6q 3541 42 were be VBD cord-006870-f5w6fw6q 3541 43 in in IN cord-006870-f5w6fw6q 3541 44 their -PRON- PRP$ cord-006870-f5w6fw6q 3541 45 fifties fifty NNS cord-006870-f5w6fw6q 3541 46 ( ( -LRB- cord-006870-f5w6fw6q 3541 47 3/54 3/54 CD cord-006870-f5w6fw6q 3541 48 ) ) -RRB- cord-006870-f5w6fw6q 3541 49 . . . cord-006870-f5w6fw6q 3542 1 Most Most JJS cord-006870-f5w6fw6q 3542 2 of of IN cord-006870-f5w6fw6q 3542 3 the the DT cord-006870-f5w6fw6q 3542 4 participating participate VBG cord-006870-f5w6fw6q 3542 5 physicians physician NNS cord-006870-f5w6fw6q 3542 6 were be VBD cord-006870-f5w6fw6q 3542 7 specialists specialist NNS cord-006870-f5w6fw6q 3542 8 in in IN cord-006870-f5w6fw6q 3542 9 emergency emergency NN cord-006870-f5w6fw6q 3542 10 or or CC cord-006870-f5w6fw6q 3542 11 intensive intensive JJ cord-006870-f5w6fw6q 3542 12 care care NN cord-006870-f5w6fw6q 3542 13 medicine medicine NN cord-006870-f5w6fw6q 3542 14 ( ( -LRB- cord-006870-f5w6fw6q 3542 15 74.1 74.1 CD cord-006870-f5w6fw6q 3542 16 % % NN cord-006870-f5w6fw6q 3542 17 ; ; : cord-006870-f5w6fw6q 3542 18 40/54 40/54 CD cord-006870-f5w6fw6q 3542 19 ) ) -RRB- cord-006870-f5w6fw6q 3542 20 ; ; : cord-006870-f5w6fw6q 3542 21 nurses nurse NNS cord-006870-f5w6fw6q 3542 22 ( ( -LRB- cord-006870-f5w6fw6q 3542 23 13.0 13.0 CD cord-006870-f5w6fw6q 3542 24 % % NN cord-006870-f5w6fw6q 3542 25 ; ; : cord-006870-f5w6fw6q 3542 26 7/54 7/54 CD cord-006870-f5w6fw6q 3542 27 ) ) -RRB- cord-006870-f5w6fw6q 3542 28 and and CC cord-006870-f5w6fw6q 3542 29 a a DT cord-006870-f5w6fw6q 3542 30 clinical clinical JJ cord-006870-f5w6fw6q 3542 31 engineer engineer NN cord-006870-f5w6fw6q 3542 32 ( ( -LRB- cord-006870-f5w6fw6q 3542 33 1.9 1.9 CD cord-006870-f5w6fw6q 3542 34 % % NN cord-006870-f5w6fw6q 3542 35 : : : cord-006870-f5w6fw6q 3542 36 1/54 1/54 LS cord-006870-f5w6fw6q 3542 37 ) ) -RRB- cord-006870-f5w6fw6q 3542 38 also also RB cord-006870-f5w6fw6q 3542 39 participated participate VBD cord-006870-f5w6fw6q 3542 40 . . . cord-006870-f5w6fw6q 3543 1 Most Most JJS cord-006870-f5w6fw6q 3543 2 participants participant NNS cord-006870-f5w6fw6q 3543 3 ( ( -LRB- cord-006870-f5w6fw6q 3543 4 81.5 81.5 CD cord-006870-f5w6fw6q 3543 5 % % NN cord-006870-f5w6fw6q 3543 6 ; ; : cord-006870-f5w6fw6q 3543 7 44/54 44/54 CD cord-006870-f5w6fw6q 3543 8 ) ) -RRB- cord-006870-f5w6fw6q 3543 9 were be VBD cord-006870-f5w6fw6q 3543 10 satisfied satisfied JJ cord-006870-f5w6fw6q 3543 11 with with IN cord-006870-f5w6fw6q 3543 12 the the DT cord-006870-f5w6fw6q 3543 13 seminar seminar NN cord-006870-f5w6fw6q 3543 14 , , , cord-006870-f5w6fw6q 3543 15 and and CC cord-006870-f5w6fw6q 3543 16 almost almost RB cord-006870-f5w6fw6q 3543 17 all all DT cord-006870-f5w6fw6q 3543 18 ( ( -LRB- cord-006870-f5w6fw6q 3544 1 98.1 98.1 CD cord-006870-f5w6fw6q 3544 2 % % NN cord-006870-f5w6fw6q 3544 3 ; ; : cord-006870-f5w6fw6q 3544 4 53/54 53/54 CD cord-006870-f5w6fw6q 3544 5 ) ) -RRB- cord-006870-f5w6fw6q 3544 6 improved improve VBD cord-006870-f5w6fw6q 3544 7 their -PRON- PRP$ cord-006870-f5w6fw6q 3544 8 self self NN cord-006870-f5w6fw6q 3544 9 - - HYPH cord-006870-f5w6fw6q 3544 10 confidence confidence NN cord-006870-f5w6fw6q 3544 11 in in IN cord-006870-f5w6fw6q 3544 12 the the DT cord-006870-f5w6fw6q 3544 13 ability ability NN cord-006870-f5w6fw6q 3544 14 to to TO cord-006870-f5w6fw6q 3544 15 carry carry VB cord-006870-f5w6fw6q 3544 16 out out RP cord-006870-f5w6fw6q 3544 17 clinical clinical JJ cord-006870-f5w6fw6q 3544 18 practice practice NN cord-006870-f5w6fw6q 3544 19 in in IN cord-006870-f5w6fw6q 3544 20 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3544 21 care care NN cord-006870-f5w6fw6q 3544 22 . . . cord-006870-f5w6fw6q 3545 1 We -PRON- PRP cord-006870-f5w6fw6q 3545 2 received receive VBD cord-006870-f5w6fw6q 3545 3 positive positive JJ cord-006870-f5w6fw6q 3545 4 , , , cord-006870-f5w6fw6q 3545 5 satisfied satisfied JJ cord-006870-f5w6fw6q 3545 6 reactions reaction NNS cord-006870-f5w6fw6q 3545 7 from from IN cord-006870-f5w6fw6q 3545 8 the the DT cord-006870-f5w6fw6q 3545 9 Japanese japanese JJ cord-006870-f5w6fw6q 3545 10 intensivists intensivist NNS cord-006870-f5w6fw6q 3545 11 who who WP cord-006870-f5w6fw6q 3545 12 participated participate VBD cord-006870-f5w6fw6q 3545 13 in in IN cord-006870-f5w6fw6q 3545 14 our -PRON- PRP$ cord-006870-f5w6fw6q 3545 15 seminar seminar NN cord-006870-f5w6fw6q 3545 16 . . . cord-006870-f5w6fw6q 3546 1 For for IN cord-006870-f5w6fw6q 3546 2 further further JJ cord-006870-f5w6fw6q 3546 3 improvement improvement NN cord-006870-f5w6fw6q 3546 4 , , , cord-006870-f5w6fw6q 3546 5 we -PRON- PRP cord-006870-f5w6fw6q 3546 6 need need VBP cord-006870-f5w6fw6q 3546 7 to to TO cord-006870-f5w6fw6q 3546 8 collect collect VB cord-006870-f5w6fw6q 3546 9 objective objective JJ cord-006870-f5w6fw6q 3546 10 data datum NNS cord-006870-f5w6fw6q 3546 11 to to TO cord-006870-f5w6fw6q 3546 12 assess assess VB cord-006870-f5w6fw6q 3546 13 the the DT cord-006870-f5w6fw6q 3546 14 utility utility NN cord-006870-f5w6fw6q 3546 15 of of IN cord-006870-f5w6fw6q 3546 16 our -PRON- PRP$ cord-006870-f5w6fw6q 3546 17 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3546 18 Care Care NNP cord-006870-f5w6fw6q 3546 19 Hands Hands NNPS cord-006870-f5w6fw6q 3546 20 - - HYPH cord-006870-f5w6fw6q 3546 21 on on IN cord-006870-f5w6fw6q 3546 22 Seminar Seminar NNP cord-006870-f5w6fw6q 3546 23 . . . cord-006870-f5w6fw6q 3547 1 Lumbar lumbar JJ cord-006870-f5w6fw6q 3547 2 puncture puncture NN cord-006870-f5w6fw6q 3547 3 in in IN cord-006870-f5w6fw6q 3547 4 the the DT cord-006870-f5w6fw6q 3547 5 presence presence NN cord-006870-f5w6fw6q 3547 6 of of IN cord-006870-f5w6fw6q 3547 7 mass mass NN cord-006870-f5w6fw6q 3547 8 effect effect NN cord-006870-f5w6fw6q 3547 9 ? ? . cord-006870-f5w6fw6q 3548 1 Ciro Ciro NNP cord-006870-f5w6fw6q 3548 2 Ramos Ramos NNP cord-006870-f5w6fw6q 3548 3 - - HYPH cord-006870-f5w6fw6q 3548 4 Estebanez Estebanez NNP cord-006870-f5w6fw6q 3548 5 UHCMC UHCMC NNP cord-006870-f5w6fw6q 3548 6 , , , cord-006870-f5w6fw6q 3549 1 Case Case NNP cord-006870-f5w6fw6q 3549 2 Western Western NNP cord-006870-f5w6fw6q 3549 3 Reserve Reserve NNP cord-006870-f5w6fw6q 3549 4 University University NNP cord-006870-f5w6fw6q 3549 5 / / SYM cord-006870-f5w6fw6q 3549 6 Neurology Neurology NNP cord-006870-f5w6fw6q 3549 7 , , , cord-006870-f5w6fw6q 3549 8 Cleveland Cleveland NNP cord-006870-f5w6fw6q 3549 9 , , , cord-006870-f5w6fw6q 3549 10 Ohio Ohio NNP cord-006870-f5w6fw6q 3549 11 , , , cord-006870-f5w6fw6q 3549 12 USA USA NNP cord-006870-f5w6fw6q 3549 13 Introduction Introduction NNP cord-006870-f5w6fw6q 3549 14 1 1 CD cord-006870-f5w6fw6q 3549 15 ) ) -RRB- cord-006870-f5w6fw6q 3550 1 We -PRON- PRP cord-006870-f5w6fw6q 3550 2 propose propose VBP cord-006870-f5w6fw6q 3550 3 an an DT cord-006870-f5w6fw6q 3550 4 international international JJ cord-006870-f5w6fw6q 3550 5 consortium consortium NN cord-006870-f5w6fw6q 3550 6 that that WDT cord-006870-f5w6fw6q 3550 7 would would MD cord-006870-f5w6fw6q 3550 8 prospectively prospectively RB cord-006870-f5w6fw6q 3550 9 confirm confirm VB cord-006870-f5w6fw6q 3550 10 the the DT cord-006870-f5w6fw6q 3550 11 safety safety NN cord-006870-f5w6fw6q 3550 12 of of IN cord-006870-f5w6fw6q 3550 13 low low JJ cord-006870-f5w6fw6q 3550 14 volume volume NN cord-006870-f5w6fw6q 3550 15 lumbar lumbar NN cord-006870-f5w6fw6q 3550 16 puncture puncture NN cord-006870-f5w6fw6q 3550 17 ( ( -LRB- cord-006870-f5w6fw6q 3550 18 LP LP NNP cord-006870-f5w6fw6q 3550 19 ) ) -RRB- cord-006870-f5w6fw6q 3550 20 in in IN cord-006870-f5w6fw6q 3550 21 the the DT cord-006870-f5w6fw6q 3550 22 presence presence NN cord-006870-f5w6fw6q 3550 23 of of IN cord-006870-f5w6fw6q 3550 24 mass mass JJ cord-006870-f5w6fw6q 3550 25 effect effect NN cord-006870-f5w6fw6q 3550 26 in in IN cord-006870-f5w6fw6q 3550 27 selected select VBN cord-006870-f5w6fw6q 3550 28 scenarios scenario NNS cord-006870-f5w6fw6q 3550 29 . . . cord-006870-f5w6fw6q 3551 1 2 2 LS cord-006870-f5w6fw6q 3551 2 ) ) -RRB- cord-006870-f5w6fw6q 3551 3 Welcome welcome VBP cord-006870-f5w6fw6q 3551 4 peers peer NNS cord-006870-f5w6fw6q 3551 5 and and CC cord-006870-f5w6fw6q 3551 6 advisors advisor NNS cord-006870-f5w6fw6q 3551 7 to to TO cord-006870-f5w6fw6q 3551 8 join join VB cord-006870-f5w6fw6q 3551 9 the the DT cord-006870-f5w6fw6q 3551 10 effort effort NN cord-006870-f5w6fw6q 3551 11 . . . cord-006870-f5w6fw6q 3552 1 LP LP NNP cord-006870-f5w6fw6q 3552 2 may may MD cord-006870-f5w6fw6q 3552 3 be be VB cord-006870-f5w6fw6q 3552 4 clinically clinically RB cord-006870-f5w6fw6q 3552 5 necessary necessary JJ cord-006870-f5w6fw6q 3552 6 in in IN cord-006870-f5w6fw6q 3552 7 the the DT cord-006870-f5w6fw6q 3552 8 presence presence NN cord-006870-f5w6fw6q 3552 9 of of IN cord-006870-f5w6fw6q 3552 10 cerebral cerebral JJ cord-006870-f5w6fw6q 3552 11 mass mass JJ cord-006870-f5w6fw6q 3552 12 effect effect NN cord-006870-f5w6fw6q 3552 13 . . . cord-006870-f5w6fw6q 3553 1 While while IN cord-006870-f5w6fw6q 3553 2 empirical empirical JJ cord-006870-f5w6fw6q 3553 3 antibiotic antibiotic JJ cord-006870-f5w6fw6q 3553 4 therapy therapy NN cord-006870-f5w6fw6q 3553 5 is be VBZ cord-006870-f5w6fw6q 3553 6 generally generally RB cord-006870-f5w6fw6q 3553 7 successful successful JJ cord-006870-f5w6fw6q 3553 8 , , , cord-006870-f5w6fw6q 3553 9 specific specific JJ cord-006870-f5w6fw6q 3553 10 groups group NNS cord-006870-f5w6fw6q 3553 11 such such JJ cord-006870-f5w6fw6q 3553 12 as as IN cord-006870-f5w6fw6q 3553 13 post post JJ cord-006870-f5w6fw6q 3553 14 - - JJ cord-006870-f5w6fw6q 3553 15 instrumentation instrumentation JJ cord-006870-f5w6fw6q 3553 16 patients patient NNS cord-006870-f5w6fw6q 3553 17 and and CC cord-006870-f5w6fw6q 3553 18 immunosuppressed immunosuppressed JJ cord-006870-f5w6fw6q 3553 19 individuals individual NNS cord-006870-f5w6fw6q 3553 20 may may MD cord-006870-f5w6fw6q 3553 21 benefit benefit VB cord-006870-f5w6fw6q 3553 22 from from IN cord-006870-f5w6fw6q 3553 23 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 3553 24 fluid fluid NN cord-006870-f5w6fw6q 3553 25 ( ( -LRB- cord-006870-f5w6fw6q 3553 26 CSF CSF NNP cord-006870-f5w6fw6q 3553 27 ) ) -RRB- cord-006870-f5w6fw6q 3553 28 studies study NNS cord-006870-f5w6fw6q 3553 29 . . . cord-006870-f5w6fw6q 3554 1 In in IN cord-006870-f5w6fw6q 3554 2 the the DT cord-006870-f5w6fw6q 3554 3 absence absence NN cord-006870-f5w6fw6q 3554 4 of of IN cord-006870-f5w6fw6q 3554 5 high high JJ cord-006870-f5w6fw6q 3554 6 - - HYPH cord-006870-f5w6fw6q 3554 7 quality quality NN cord-006870-f5w6fw6q 3554 8 clinical clinical JJ cord-006870-f5w6fw6q 3554 9 recommendations recommendation NNS cord-006870-f5w6fw6q 3554 10 , , , cord-006870-f5w6fw6q 3554 11 uncontrolled uncontrolled JJ cord-006870-f5w6fw6q 3554 12 retrospective retrospective JJ cord-006870-f5w6fw6q 3554 13 literature literature NN cord-006870-f5w6fw6q 3554 14 suggests suggest VBZ cord-006870-f5w6fw6q 3554 15 that that IN cord-006870-f5w6fw6q 3554 16 a a DT cord-006870-f5w6fw6q 3554 17 small small JJ cord-006870-f5w6fw6q 3554 18 volume volume NN cord-006870-f5w6fw6q 3554 19 LP LP NNP cord-006870-f5w6fw6q 3554 20 ( ( -LRB- cord-006870-f5w6fw6q 3554 21 5 5 CD cord-006870-f5w6fw6q 3554 22 - - SYM cord-006870-f5w6fw6q 3554 23 10 10 CD cord-006870-f5w6fw6q 3554 24 cc cc NN cord-006870-f5w6fw6q 3554 25 ) ) -RRB- cord-006870-f5w6fw6q 3554 26 might may MD cord-006870-f5w6fw6q 3554 27 be be VB cord-006870-f5w6fw6q 3554 28 without without IN cord-006870-f5w6fw6q 3554 29 complications complication NNS cord-006870-f5w6fw6q 3554 30 in in IN cord-006870-f5w6fw6q 3554 31 specific specific JJ cord-006870-f5w6fw6q 3554 32 situations situation NNS cord-006870-f5w6fw6q 3554 33 . . . cord-006870-f5w6fw6q 3555 1 Nevertheless nevertheless RB cord-006870-f5w6fw6q 3555 2 , , , cord-006870-f5w6fw6q 3555 3 the the DT cord-006870-f5w6fw6q 3555 4 ethical ethical JJ cord-006870-f5w6fw6q 3555 5 principle principle NN cord-006870-f5w6fw6q 3555 6 of of IN cord-006870-f5w6fw6q 3555 7 non non JJ cord-006870-f5w6fw6q 3555 8 - - NN cord-006870-f5w6fw6q 3555 9 maleficence maleficence JJ cord-006870-f5w6fw6q 3555 10 and and CC cord-006870-f5w6fw6q 3555 11 the the DT cord-006870-f5w6fw6q 3555 12 liability liability NN cord-006870-f5w6fw6q 3555 13 risk risk NN cord-006870-f5w6fw6q 3555 14 prevent prevent VB cord-006870-f5w6fw6q 3555 15 clinicians clinician NNS cord-006870-f5w6fw6q 3555 16 from from IN cord-006870-f5w6fw6q 3555 17 performing perform VBG cord-006870-f5w6fw6q 3555 18 LPs lp NNS cord-006870-f5w6fw6q 3555 19 . . . cord-006870-f5w6fw6q 3556 1 In in IN cord-006870-f5w6fw6q 3556 2 this this DT cord-006870-f5w6fw6q 3556 3 scenario scenario NN cord-006870-f5w6fw6q 3556 4 , , , cord-006870-f5w6fw6q 3556 5 an an DT cord-006870-f5w6fw6q 3556 6 extended extended JJ cord-006870-f5w6fw6q 3556 7 length length NN cord-006870-f5w6fw6q 3556 8 of of IN cord-006870-f5w6fw6q 3556 9 stay stay NN cord-006870-f5w6fw6q 3556 10 , , , cord-006870-f5w6fw6q 3556 11 poor poor JJ cord-006870-f5w6fw6q 3556 12 outcomes outcome NNS cord-006870-f5w6fw6q 3556 13 , , , cord-006870-f5w6fw6q 3556 14 or or CC cord-006870-f5w6fw6q 3556 15 a a DT cord-006870-f5w6fw6q 3556 16 higher high JJR cord-006870-f5w6fw6q 3556 17 cost cost NN cord-006870-f5w6fw6q 3556 18 of of IN cord-006870-f5w6fw6q 3556 19 care care NN cord-006870-f5w6fw6q 3556 20 are be VBP cord-006870-f5w6fw6q 3556 21 legitimate legitimate JJ cord-006870-f5w6fw6q 3556 22 concerns concern NNS cord-006870-f5w6fw6q 3556 23 . . . cord-006870-f5w6fw6q 3557 1 Synthesize synthesize VB cord-006870-f5w6fw6q 3557 2 an an DT cord-006870-f5w6fw6q 3557 3 external external JJ cord-006870-f5w6fw6q 3557 4 peer peer NN cord-006870-f5w6fw6q 3557 5 reviewed review VBN cord-006870-f5w6fw6q 3557 6 methodology methodology NN cord-006870-f5w6fw6q 3557 7 to to TO cord-006870-f5w6fw6q 3557 8 maintain maintain VB cord-006870-f5w6fw6q 3557 9 rigour rigour NN cord-006870-f5w6fw6q 3557 10 and and CC cord-006870-f5w6fw6q 3557 11 transparency transparency NN cord-006870-f5w6fw6q 3557 12 . . . cord-006870-f5w6fw6q 3558 1 6 6 LS cord-006870-f5w6fw6q 3558 2 . . . cord-006870-f5w6fw6q 3559 1 Seek seek VB cord-006870-f5w6fw6q 3559 2 appraisal appraisal NN cord-006870-f5w6fw6q 3559 3 , , , cord-006870-f5w6fw6q 3559 4 approval approval NN cord-006870-f5w6fw6q 3559 5 and and CC cord-006870-f5w6fw6q 3559 6 endorsement endorsement NN cord-006870-f5w6fw6q 3559 7 of of IN cord-006870-f5w6fw6q 3559 8 national national JJ cord-006870-f5w6fw6q 3559 9 and and CC cord-006870-f5w6fw6q 3559 10 international international JJ cord-006870-f5w6fw6q 3559 11 Quality Quality NNP cord-006870-f5w6fw6q 3559 12 Improvement Improvement NNP cord-006870-f5w6fw6q 3559 13 Committees Committees NNPS cord-006870-f5w6fw6q 3559 14 . . . cord-006870-f5w6fw6q 3560 1 7 7 CD cord-006870-f5w6fw6q 3560 2 . . . cord-006870-f5w6fw6q 3561 1 Generate generate VB cord-006870-f5w6fw6q 3561 2 and and CC cord-006870-f5w6fw6q 3561 3 assimilate assimilate VB cord-006870-f5w6fw6q 3561 4 the the DT cord-006870-f5w6fw6q 3561 5 most most RBS cord-006870-f5w6fw6q 3561 6 current current JJ cord-006870-f5w6fw6q 3561 7 clinical clinical JJ cord-006870-f5w6fw6q 3561 8 evidence evidence NN cord-006870-f5w6fw6q 3561 9 through through IN cord-006870-f5w6fw6q 3561 10 : : : cord-006870-f5w6fw6q 3561 11 A. A. NNP cord-006870-f5w6fw6q 3561 12 Systematic systematic JJ cord-006870-f5w6fw6q 3561 13 review review NN cord-006870-f5w6fw6q 3561 14 and and CC cord-006870-f5w6fw6q 3561 15 meta meta NN cord-006870-f5w6fw6q 3561 16 - - HYPH cord-006870-f5w6fw6q 3561 17 analysis analysis NN cord-006870-f5w6fw6q 3561 18 . . . cord-006870-f5w6fw6q 3562 1 B. B. NNP cord-006870-f5w6fw6q 3562 2 Prospective Prospective NNP cord-006870-f5w6fw6q 3562 3 randomized randomize VBD cord-006870-f5w6fw6q 3562 4 controlled control VBN cord-006870-f5w6fw6q 3562 5 clinical clinical JJ cord-006870-f5w6fw6q 3562 6 trial trial NN cord-006870-f5w6fw6q 3562 7 . . . cord-006870-f5w6fw6q 3563 1 8 8 CD cord-006870-f5w6fw6q 3563 2 . . . cord-006870-f5w6fw6q 3564 1 Construct construct VB cord-006870-f5w6fw6q 3564 2 a a DT cord-006870-f5w6fw6q 3564 3 protocol protocol NN cord-006870-f5w6fw6q 3564 4 to to TO cord-006870-f5w6fw6q 3564 5 inform inform VB cord-006870-f5w6fw6q 3564 6 decision decision NN cord-006870-f5w6fw6q 3564 7 making make VBG cord-006870-f5w6fw6q 3564 8 amongst amongst IN cord-006870-f5w6fw6q 3564 9 healthcare healthcare NN cord-006870-f5w6fw6q 3564 10 and and CC cord-006870-f5w6fw6q 3564 11 non non JJ cord-006870-f5w6fw6q 3564 12 - - JJ cord-006870-f5w6fw6q 3564 13 healthcare healthcare JJ cord-006870-f5w6fw6q 3564 14 personnel personnel NNS cord-006870-f5w6fw6q 3564 15 . . . cord-006870-f5w6fw6q 3565 1 9 9 LS cord-006870-f5w6fw6q 3565 2 . . . cord-006870-f5w6fw6q 3566 1 Dissemination dissemination NN cord-006870-f5w6fw6q 3566 2 and and CC cord-006870-f5w6fw6q 3566 3 implementation implementation NN cord-006870-f5w6fw6q 3566 4 . . . cord-006870-f5w6fw6q 3567 1 10 10 CD cord-006870-f5w6fw6q 3567 2 . . . cord-006870-f5w6fw6q 3568 1 Schedule schedule NN cord-006870-f5w6fw6q 3568 2 updates update NNS cord-006870-f5w6fw6q 3568 3 and/or and/or CC cord-006870-f5w6fw6q 3568 4 revision revision NN cord-006870-f5w6fw6q 3568 5 . . . cord-006870-f5w6fw6q 3569 1 15 15 CD cord-006870-f5w6fw6q 3569 2 centers center NNS cord-006870-f5w6fw6q 3569 3 across across IN cord-006870-f5w6fw6q 3569 4 the the DT cord-006870-f5w6fw6q 3569 5 globe globe NN cord-006870-f5w6fw6q 3569 6 ( ( -LRB- cord-006870-f5w6fw6q 3569 7 North North NNP cord-006870-f5w6fw6q 3569 8 America America NNP cord-006870-f5w6fw6q 3569 9 = = SYM cord-006870-f5w6fw6q 3569 10 5 5 CD cord-006870-f5w6fw6q 3569 11 , , , cord-006870-f5w6fw6q 3569 12 South South NNP cord-006870-f5w6fw6q 3569 13 America=4 America=4 NNP cord-006870-f5w6fw6q 3569 14 , , , cord-006870-f5w6fw6q 3569 15 Europe=2 europe=2 CD cord-006870-f5w6fw6q 3569 16 , , , cord-006870-f5w6fw6q 3570 1 and and CC cord-006870-f5w6fw6q 3570 2 Asia=5 Asia=5 NNP cord-006870-f5w6fw6q 3570 3 ) ) -RRB- cord-006870-f5w6fw6q 3570 4 have have VBP cord-006870-f5w6fw6q 3570 5 agreed agree VBN cord-006870-f5w6fw6q 3570 6 to to TO cord-006870-f5w6fw6q 3570 7 establish establish VB cord-006870-f5w6fw6q 3570 8 an an DT cord-006870-f5w6fw6q 3570 9 LP LP NNP cord-006870-f5w6fw6q 3570 10 consortium consortium NN cord-006870-f5w6fw6q 3570 11 so so RB cord-006870-f5w6fw6q 3570 12 far far RB cord-006870-f5w6fw6q 3570 13 . . . cord-006870-f5w6fw6q 3571 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 3571 2 analyses analysis NNS cord-006870-f5w6fw6q 3571 3 suggest suggest VBP cord-006870-f5w6fw6q 3571 4 low low JJ cord-006870-f5w6fw6q 3571 5 - - HYPH cord-006870-f5w6fw6q 3571 6 volume volume NN cord-006870-f5w6fw6q 3571 7 LP LP NNP cord-006870-f5w6fw6q 3571 8 's 's POS cord-006870-f5w6fw6q 3571 9 relative relative JJ cord-006870-f5w6fw6q 3571 10 safety safety NN cord-006870-f5w6fw6q 3571 11 in in IN cord-006870-f5w6fw6q 3571 12 the the DT cord-006870-f5w6fw6q 3571 13 presence presence NN cord-006870-f5w6fw6q 3571 14 of of IN cord-006870-f5w6fw6q 3571 15 increased increase VBN cord-006870-f5w6fw6q 3571 16 ICP ICP NNP cord-006870-f5w6fw6q 3571 17 . . . cord-006870-f5w6fw6q 3572 1 Thereby thereby RB cord-006870-f5w6fw6q 3572 2 , , , cord-006870-f5w6fw6q 3572 3 an an DT cord-006870-f5w6fw6q 3572 4 expert expert JJ cord-006870-f5w6fw6q 3572 5 consortium consortium NN cord-006870-f5w6fw6q 3572 6 trusted trust VBN cord-006870-f5w6fw6q 3572 7 with with IN cord-006870-f5w6fw6q 3572 8 prospective prospective JJ cord-006870-f5w6fw6q 3572 9 verification verification NN cord-006870-f5w6fw6q 3572 10 would would MD cord-006870-f5w6fw6q 3572 11 potentially potentially RB cord-006870-f5w6fw6q 3572 12 benefit benefit VB cord-006870-f5w6fw6q 3572 13 specific specific JJ cord-006870-f5w6fw6q 3572 14 patient patient NN cord-006870-f5w6fw6q 3572 15 populations population NNS cord-006870-f5w6fw6q 3572 16 . . . cord-006870-f5w6fw6q 3573 1 Patient patient JJ cord-006870-f5w6fw6q 3573 2 centered center VBN cord-006870-f5w6fw6q 3573 3 decision decision NN cord-006870-f5w6fw6q 3573 4 making making NN cord-006870-f5w6fw6q 3573 5 in in IN cord-006870-f5w6fw6q 3573 6 the the DT cord-006870-f5w6fw6q 3573 7 NCCU NCCU NNP cord-006870-f5w6fw6q 3573 8 requires require VBZ cord-006870-f5w6fw6q 3573 9 family family NN cord-006870-f5w6fw6q 3573 10 members member NNS cord-006870-f5w6fw6q 3573 11 understanding understanding NN cord-006870-f5w6fw6q 3573 12 of of IN cord-006870-f5w6fw6q 3573 13 their -PRON- PRP$ cord-006870-f5w6fw6q 3573 14 loved love VBN cord-006870-f5w6fw6q 3573 15 one one NN cord-006870-f5w6fw6q 3573 16 's 's POS cord-006870-f5w6fw6q 3573 17 preferences preference NNS cord-006870-f5w6fw6q 3573 18 and and CC cord-006870-f5w6fw6q 3573 19 values value NNS cord-006870-f5w6fw6q 3573 20 as as RB cord-006870-f5w6fw6q 3573 21 well well RB cord-006870-f5w6fw6q 3573 22 as as IN cord-006870-f5w6fw6q 3573 23 the the DT cord-006870-f5w6fw6q 3573 24 complexities complexity NNS cord-006870-f5w6fw6q 3573 25 of of IN cord-006870-f5w6fw6q 3573 26 their -PRON- PRP$ cord-006870-f5w6fw6q 3573 27 medical medical JJ cord-006870-f5w6fw6q 3573 28 condition condition NN cord-006870-f5w6fw6q 3573 29 and and CC cord-006870-f5w6fw6q 3573 30 treatments treatment NNS cord-006870-f5w6fw6q 3573 31 . . . cord-006870-f5w6fw6q 3574 1 Family family NN cord-006870-f5w6fw6q 3574 2 - - HYPH cord-006870-f5w6fw6q 3574 3 Centered Centered NNP cord-006870-f5w6fw6q 3574 4 Care Care NNP cord-006870-f5w6fw6q 3574 5 ( ( -LRB- cord-006870-f5w6fw6q 3574 6 FCC FCC NNP cord-006870-f5w6fw6q 3574 7 ) ) -RRB- cord-006870-f5w6fw6q 3574 8 is be VBZ cord-006870-f5w6fw6q 3574 9 essential essential JJ cord-006870-f5w6fw6q 3574 10 so so IN cord-006870-f5w6fw6q 3574 11 that that IN cord-006870-f5w6fw6q 3574 12 family family NN cord-006870-f5w6fw6q 3574 13 members member NNS cord-006870-f5w6fw6q 3574 14 are be VBP cord-006870-f5w6fw6q 3574 15 actively actively RB cord-006870-f5w6fw6q 3574 16 involved involve VBN cord-006870-f5w6fw6q 3574 17 in in IN cord-006870-f5w6fw6q 3574 18 decision decision NN cord-006870-f5w6fw6q 3574 19 - - HYPH cord-006870-f5w6fw6q 3574 20 making making NN cord-006870-f5w6fw6q 3574 21 . . . cord-006870-f5w6fw6q 3575 1 Stakeholders stakeholder NNS cord-006870-f5w6fw6q 3575 2 have have VBP cord-006870-f5w6fw6q 3575 3 reported report VBN cord-006870-f5w6fw6q 3575 4 their -PRON- PRP$ cord-006870-f5w6fw6q 3575 5 preference preference NN cord-006870-f5w6fw6q 3575 6 to to TO cord-006870-f5w6fw6q 3575 7 receive receive VB cord-006870-f5w6fw6q 3575 8 prognostic prognostic JJ cord-006870-f5w6fw6q 3575 9 information information NN cord-006870-f5w6fw6q 3575 10 in in IN cord-006870-f5w6fw6q 3575 11 smaller small JJR cord-006870-f5w6fw6q 3575 12 packets packet NNS cord-006870-f5w6fw6q 3575 13 and and CC cord-006870-f5w6fw6q 3575 14 recapitulated recapitulate VBN cord-006870-f5w6fw6q 3575 15 in in IN cord-006870-f5w6fw6q 3575 16 different different JJ cord-006870-f5w6fw6q 3575 17 venues venue NNS cord-006870-f5w6fw6q 3575 18 including include VBG cord-006870-f5w6fw6q 3575 19 rounds round NNS cord-006870-f5w6fw6q 3575 20 , , , cord-006870-f5w6fw6q 3575 21 bedside bedside NN cord-006870-f5w6fw6q 3575 22 and and CC cord-006870-f5w6fw6q 3575 23 care care NN cord-006870-f5w6fw6q 3575 24 conferences conference NNS cord-006870-f5w6fw6q 3575 25 . . . cord-006870-f5w6fw6q 3576 1 We -PRON- PRP cord-006870-f5w6fw6q 3576 2 examine examine VBP cord-006870-f5w6fw6q 3576 3 implementation implementation NN cord-006870-f5w6fw6q 3576 4 of of IN cord-006870-f5w6fw6q 3576 5 a a DT cord-006870-f5w6fw6q 3576 6 multimodal multimodal NN cord-006870-f5w6fw6q 3576 7 communication communication NN cord-006870-f5w6fw6q 3576 8 strategy strategy NN cord-006870-f5w6fw6q 3576 9 on on IN cord-006870-f5w6fw6q 3576 10 clinician clinician NN cord-006870-f5w6fw6q 3576 11 utilization utilization NN cord-006870-f5w6fw6q 3576 12 , , , cord-006870-f5w6fw6q 3576 13 family family NN cord-006870-f5w6fw6q 3576 14 engagement engagement NN cord-006870-f5w6fw6q 3576 15 and and CC cord-006870-f5w6fw6q 3576 16 satisfaction satisfaction NN cord-006870-f5w6fw6q 3576 17 in in IN cord-006870-f5w6fw6q 3576 18 the the DT cord-006870-f5w6fw6q 3576 19 NCCU NCCU NNP cord-006870-f5w6fw6q 3576 20 . . . cord-006870-f5w6fw6q 3577 1 An an DT cord-006870-f5w6fw6q 3577 2 interdisciplinary interdisciplinary JJ cord-006870-f5w6fw6q 3577 3 team team NN cord-006870-f5w6fw6q 3577 4 convened convene VBD cord-006870-f5w6fw6q 3577 5 to to TO cord-006870-f5w6fw6q 3577 6 develop develop VB cord-006870-f5w6fw6q 3577 7 a a DT cord-006870-f5w6fw6q 3577 8 plan plan NN cord-006870-f5w6fw6q 3577 9 implementing implement VBG cord-006870-f5w6fw6q 3577 10 a a DT cord-006870-f5w6fw6q 3577 11 multimodal multimodal NN cord-006870-f5w6fw6q 3577 12 communication communication NN cord-006870-f5w6fw6q 3577 13 strategy strategy NN cord-006870-f5w6fw6q 3577 14 . . . cord-006870-f5w6fw6q 3578 1 Pre pre JJ cord-006870-f5w6fw6q 3578 2 - - JJ cord-006870-f5w6fw6q 3578 3 implementation implementation JJ cord-006870-f5w6fw6q 3578 4 survey survey NN cord-006870-f5w6fw6q 3578 5 of of IN cord-006870-f5w6fw6q 3578 6 clinicians clinician NNS cord-006870-f5w6fw6q 3578 7 ( ( -LRB- cord-006870-f5w6fw6q 3578 8 MDs MDs NNP cord-006870-f5w6fw6q 3578 9 , , , cord-006870-f5w6fw6q 3578 10 NPs NPs NNP cord-006870-f5w6fw6q 3578 11 , , , cord-006870-f5w6fw6q 3578 12 RNs RNs NNP cord-006870-f5w6fw6q 3578 13 , , , cord-006870-f5w6fw6q 3578 14 etc etc FW cord-006870-f5w6fw6q 3578 15 . . . cord-006870-f5w6fw6q 3578 16 ) ) -RRB- cord-006870-f5w6fw6q 3579 1 and and CC cord-006870-f5w6fw6q 3579 2 patient patient JJ cord-006870-f5w6fw6q 3579 3 families family NNS cord-006870-f5w6fw6q 3579 4 was be VBD cord-006870-f5w6fw6q 3579 5 completed complete VBN cord-006870-f5w6fw6q 3579 6 to to TO cord-006870-f5w6fw6q 3579 7 determine determine VB cord-006870-f5w6fw6q 3579 8 the the DT cord-006870-f5w6fw6q 3579 9 level level NN cord-006870-f5w6fw6q 3579 10 of of IN cord-006870-f5w6fw6q 3579 11 family family NN cord-006870-f5w6fw6q 3579 12 engagement engagement NN cord-006870-f5w6fw6q 3579 13 already already RB cord-006870-f5w6fw6q 3579 14 in in IN cord-006870-f5w6fw6q 3579 15 place place NN cord-006870-f5w6fw6q 3579 16 in in IN cord-006870-f5w6fw6q 3579 17 the the DT cord-006870-f5w6fw6q 3579 18 NCCU NCCU NNP cord-006870-f5w6fw6q 3579 19 . . . cord-006870-f5w6fw6q 3580 1 Four four CD cord-006870-f5w6fw6q 3580 2 interventions intervention NNS cord-006870-f5w6fw6q 3580 3 were be VBD cord-006870-f5w6fw6q 3580 4 implemented implement VBN cord-006870-f5w6fw6q 3580 5 : : : cord-006870-f5w6fw6q 3580 6 family family NN cord-006870-f5w6fw6q 3580 7 communication communication NN cord-006870-f5w6fw6q 3580 8 boards board NNS cord-006870-f5w6fw6q 3580 9 were be VBD cord-006870-f5w6fw6q 3580 10 installed instal VBN cord-006870-f5w6fw6q 3580 11 in in IN cord-006870-f5w6fw6q 3580 12 patient patient JJ cord-006870-f5w6fw6q 3580 13 rooms room NNS cord-006870-f5w6fw6q 3580 14 ; ; : cord-006870-f5w6fw6q 3580 15 family family NN cord-006870-f5w6fw6q 3580 16 engagement engagement NN cord-006870-f5w6fw6q 3580 17 pamphlets pamphlet NNS cord-006870-f5w6fw6q 3580 18 developed develop VBN cord-006870-f5w6fw6q 3580 19 ; ; : cord-006870-f5w6fw6q 3580 20 a a DT cord-006870-f5w6fw6q 3580 21 script script NN cord-006870-f5w6fw6q 3580 22 and and CC cord-006870-f5w6fw6q 3580 23 schedule schedule NN cord-006870-f5w6fw6q 3580 24 for for IN cord-006870-f5w6fw6q 3580 25 family family NN cord-006870-f5w6fw6q 3580 26 care care NN cord-006870-f5w6fw6q 3580 27 rounds round NNS cord-006870-f5w6fw6q 3580 28 was be VBD cord-006870-f5w6fw6q 3580 29 developed develop VBN cord-006870-f5w6fw6q 3580 30 ; ; : cord-006870-f5w6fw6q 3580 31 nursing nursing NN cord-006870-f5w6fw6q 3580 32 and and CC cord-006870-f5w6fw6q 3580 33 provider provider NN cord-006870-f5w6fw6q 3580 34 staff staff NN cord-006870-f5w6fw6q 3580 35 were be VBD cord-006870-f5w6fw6q 3580 36 educated educate VBN cord-006870-f5w6fw6q 3580 37 on on IN cord-006870-f5w6fw6q 3580 38 inviting invite VBG cord-006870-f5w6fw6q 3580 39 families family NNS cord-006870-f5w6fw6q 3580 40 to to TO cord-006870-f5w6fw6q 3580 41 participate participate VB cord-006870-f5w6fw6q 3580 42 in in IN cord-006870-f5w6fw6q 3580 43 patient patient JJ cord-006870-f5w6fw6q 3580 44 care care NN cord-006870-f5w6fw6q 3580 45 team team NN cord-006870-f5w6fw6q 3580 46 rounds round NNS cord-006870-f5w6fw6q 3580 47 . . . cord-006870-f5w6fw6q 3581 1 Family family NN cord-006870-f5w6fw6q 3581 2 involvement involvement NN cord-006870-f5w6fw6q 3581 3 on on IN cord-006870-f5w6fw6q 3581 4 patient patient JJ cord-006870-f5w6fw6q 3581 5 care care NN cord-006870-f5w6fw6q 3581 6 rounds round NNS cord-006870-f5w6fw6q 3581 7 and and CC cord-006870-f5w6fw6q 3581 8 family family NN cord-006870-f5w6fw6q 3581 9 conferences conference NNS cord-006870-f5w6fw6q 3581 10 was be VBD cord-006870-f5w6fw6q 3581 11 compared compare VBN cord-006870-f5w6fw6q 3581 12 before before RB cord-006870-f5w6fw6q 3581 13 and and CC cord-006870-f5w6fw6q 3581 14 after after IN cord-006870-f5w6fw6q 3581 15 the the DT cord-006870-f5w6fw6q 3581 16 implementation implementation NN cord-006870-f5w6fw6q 3581 17 of of IN cord-006870-f5w6fw6q 3581 18 the the DT cord-006870-f5w6fw6q 3581 19 4 4 CD cord-006870-f5w6fw6q 3581 20 best good JJS cord-006870-f5w6fw6q 3581 21 practice practice NN cord-006870-f5w6fw6q 3581 22 initiatives initiative NNS cord-006870-f5w6fw6q 3581 23 . . . cord-006870-f5w6fw6q 3582 1 Additionally additionally RB cord-006870-f5w6fw6q 3582 2 , , , cord-006870-f5w6fw6q 3582 3 pre pre VB cord-006870-f5w6fw6q 3582 4 and and CC cord-006870-f5w6fw6q 3582 5 post post VB cord-006870-f5w6fw6q 3582 6 implementation implementation NN cord-006870-f5w6fw6q 3582 7 patient patient JJ cord-006870-f5w6fw6q 3582 8 satisfaction satisfaction NN cord-006870-f5w6fw6q 3582 9 survey survey NN cord-006870-f5w6fw6q 3582 10 results result NNS cord-006870-f5w6fw6q 3582 11 were be VBD cord-006870-f5w6fw6q 3582 12 also also RB cord-006870-f5w6fw6q 3582 13 compared compare VBN cord-006870-f5w6fw6q 3582 14 to to TO cord-006870-f5w6fw6q 3582 15 evaluate evaluate VB cord-006870-f5w6fw6q 3582 16 the the DT cord-006870-f5w6fw6q 3582 17 project project NN cord-006870-f5w6fw6q 3582 18 's 's POS cord-006870-f5w6fw6q 3582 19 success success NN cord-006870-f5w6fw6q 3582 20 . . . cord-006870-f5w6fw6q 3583 1 Pre pre JJ cord-006870-f5w6fw6q 3583 2 - - JJ cord-006870-f5w6fw6q 3583 3 implementation implementation JJ cord-006870-f5w6fw6q 3583 4 data datum NNS cord-006870-f5w6fw6q 3583 5 was be VBD cord-006870-f5w6fw6q 3583 6 collected collect VBN cord-006870-f5w6fw6q 3583 7 from from IN cord-006870-f5w6fw6q 3583 8 October October NNP cord-006870-f5w6fw6q 3583 9 -November -November NNP cord-006870-f5w6fw6q 3583 10 2016 2016 CD cord-006870-f5w6fw6q 3583 11 . . . cord-006870-f5w6fw6q 3584 1 Sixty sixty CD cord-006870-f5w6fw6q 3584 2 - - HYPH cord-006870-f5w6fw6q 3584 3 one one CD cord-006870-f5w6fw6q 3584 4 clinician clinician NN cord-006870-f5w6fw6q 3584 5 surveys survey NNS cord-006870-f5w6fw6q 3584 6 and and CC cord-006870-f5w6fw6q 3584 7 forty forty CD cord-006870-f5w6fw6q 3584 8 family family NN cord-006870-f5w6fw6q 3584 9 surveys survey NNS cord-006870-f5w6fw6q 3584 10 found find VBD cord-006870-f5w6fw6q 3584 11 that that IN cord-006870-f5w6fw6q 3584 12 family family NN cord-006870-f5w6fw6q 3584 13 more more RBR cord-006870-f5w6fw6q 3584 14 consistently consistently RB cord-006870-f5w6fw6q 3584 15 participated participate VBN cord-006870-f5w6fw6q 3584 16 on on IN cord-006870-f5w6fw6q 3584 17 daily daily JJ cord-006870-f5w6fw6q 3584 18 rounds round NNS cord-006870-f5w6fw6q 3584 19 . . . cord-006870-f5w6fw6q 3585 1 Baseline baseline JJ cord-006870-f5w6fw6q 3585 2 and and CC cord-006870-f5w6fw6q 3585 3 postimplementation postimplementation NN cord-006870-f5w6fw6q 3585 4 surveys survey NNS cord-006870-f5w6fw6q 3585 5 demonstrated demonstrate VBD cord-006870-f5w6fw6q 3585 6 families family NNS cord-006870-f5w6fw6q 3585 7 feeling feel VBG cord-006870-f5w6fw6q 3585 8 supported support VBN cord-006870-f5w6fw6q 3585 9 during during IN cord-006870-f5w6fw6q 3585 10 the the DT cord-006870-f5w6fw6q 3585 11 decision decision NN cord-006870-f5w6fw6q 3585 12 - - HYPH cord-006870-f5w6fw6q 3585 13 making make VBG cord-006870-f5w6fw6q 3585 14 process process NN cord-006870-f5w6fw6q 3585 15 . . . cord-006870-f5w6fw6q 3586 1 The the DT cord-006870-f5w6fw6q 3586 2 implementation implementation NN cord-006870-f5w6fw6q 3586 3 of of IN cord-006870-f5w6fw6q 3586 4 a a DT cord-006870-f5w6fw6q 3586 5 multimodal multimodal NN cord-006870-f5w6fw6q 3586 6 communication communication NN cord-006870-f5w6fw6q 3586 7 framework framework NN cord-006870-f5w6fw6q 3586 8 to to TO cord-006870-f5w6fw6q 3586 9 achieve achieve VB cord-006870-f5w6fw6q 3586 10 consistent consistent JJ cord-006870-f5w6fw6q 3586 11 family family NN cord-006870-f5w6fw6q 3586 12 engagement engagement NN cord-006870-f5w6fw6q 3586 13 and and CC cord-006870-f5w6fw6q 3586 14 communication communication NN cord-006870-f5w6fw6q 3586 15 has have VBZ cord-006870-f5w6fw6q 3586 16 led lead VBN cord-006870-f5w6fw6q 3586 17 to to IN cord-006870-f5w6fw6q 3586 18 an an DT cord-006870-f5w6fw6q 3586 19 appreciable appreciable JJ cord-006870-f5w6fw6q 3586 20 change change NN cord-006870-f5w6fw6q 3586 21 in in IN cord-006870-f5w6fw6q 3586 22 utilization utilization NN cord-006870-f5w6fw6q 3586 23 by by IN cord-006870-f5w6fw6q 3586 24 clinicians clinician NNS cord-006870-f5w6fw6q 3586 25 . . . cord-006870-f5w6fw6q 3587 1 Its -PRON- PRP$ cord-006870-f5w6fw6q 3587 2 use use NN cord-006870-f5w6fw6q 3587 3 is be VBZ cord-006870-f5w6fw6q 3587 4 supported support VBN cord-006870-f5w6fw6q 3587 5 by by IN cord-006870-f5w6fw6q 3587 6 consistent consistent JJ cord-006870-f5w6fw6q 3587 7 positive positive JJ cord-006870-f5w6fw6q 3587 8 family family NN cord-006870-f5w6fw6q 3587 9 attitudes attitude NNS cord-006870-f5w6fw6q 3587 10 towards towards IN cord-006870-f5w6fw6q 3587 11 communication communication NN cord-006870-f5w6fw6q 3587 12 and and CC cord-006870-f5w6fw6q 3587 13 availability availability NN cord-006870-f5w6fw6q 3587 14 of of IN cord-006870-f5w6fw6q 3587 15 information information NN cord-006870-f5w6fw6q 3587 16 in in IN cord-006870-f5w6fw6q 3587 17 the the DT cord-006870-f5w6fw6q 3587 18 NCCU NCCU NNP cord-006870-f5w6fw6q 3587 19 . . . cord-006870-f5w6fw6q 3588 1 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3588 2 Care Care NNP cord-006870-f5w6fw6q 3588 3 Society Society NNP cord-006870-f5w6fw6q 3588 4 undertook undertake VBD cord-006870-f5w6fw6q 3588 5 initiatives initiative NNS cord-006870-f5w6fw6q 3588 6 to to TO cord-006870-f5w6fw6q 3588 7 integrate integrate VB cord-006870-f5w6fw6q 3588 8 social social JJ cord-006870-f5w6fw6q 3588 9 media medium NNS cord-006870-f5w6fw6q 3588 10 in in IN cord-006870-f5w6fw6q 3588 11 member member NN cord-006870-f5w6fw6q 3588 12 engagement engagement NN cord-006870-f5w6fw6q 3588 13 activities activity NNS cord-006870-f5w6fw6q 3588 14 and and CC cord-006870-f5w6fw6q 3588 15 initiated initiate VBD cord-006870-f5w6fw6q 3588 16 a a DT cord-006870-f5w6fw6q 3588 17 Twitter Twitter NNP cord-006870-f5w6fw6q 3588 18 Journal Journal NNP cord-006870-f5w6fw6q 3588 19 Club Club NNP cord-006870-f5w6fw6q 3588 20 ( ( -LRB- cord-006870-f5w6fw6q 3588 21 # # $ cord-006870-f5w6fw6q 3588 22 NCSTJC NCSTJC NNP cord-006870-f5w6fw6q 3588 23 ) ) -RRB- cord-006870-f5w6fw6q 3588 24 in in IN cord-006870-f5w6fw6q 3588 25 2015 2015 CD cord-006870-f5w6fw6q 3588 26 with with IN cord-006870-f5w6fw6q 3588 27 the the DT cord-006870-f5w6fw6q 3588 28 first first JJ cord-006870-f5w6fw6q 3588 29 Journal Journal NNP cord-006870-f5w6fw6q 3588 30 Club Club NNP cord-006870-f5w6fw6q 3588 31 conducted conduct VBN cord-006870-f5w6fw6q 3588 32 in in IN cord-006870-f5w6fw6q 3588 33 February February NNP cord-006870-f5w6fw6q 3588 34 2015 2015 CD cord-006870-f5w6fw6q 3588 35 . . . cord-006870-f5w6fw6q 3589 1 Articles article NNS cord-006870-f5w6fw6q 3589 2 were be VBD cord-006870-f5w6fw6q 3589 3 chosen choose VBN cord-006870-f5w6fw6q 3589 4 by by IN cord-006870-f5w6fw6q 3589 5 a a DT cord-006870-f5w6fw6q 3589 6 subgroup subgroup NN cord-006870-f5w6fw6q 3589 7 of of IN cord-006870-f5w6fw6q 3589 8 the the DT cord-006870-f5w6fw6q 3589 9 Communications Communications NNPS cord-006870-f5w6fw6q 3589 10 Committee Committee NNP cord-006870-f5w6fw6q 3589 11 in in IN cord-006870-f5w6fw6q 3589 12 consultation consultation NN cord-006870-f5w6fw6q 3589 13 with with IN cord-006870-f5w6fw6q 3589 14 Dr. Dr. NNP cord-006870-f5w6fw6q 3589 15 Eelco Eelco NNP cord-006870-f5w6fw6q 3589 16 Wijdicks Wijdicks NNP cord-006870-f5w6fw6q 3589 17 , , , cord-006870-f5w6fw6q 3589 18 Chief Chief NNP cord-006870-f5w6fw6q 3589 19 Editor Editor NNP cord-006870-f5w6fw6q 3589 20 , , , cord-006870-f5w6fw6q 3589 21 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3589 22 Care Care NNP cord-006870-f5w6fw6q 3589 23 Journal Journal NNP cord-006870-f5w6fw6q 3589 24 . . . cord-006870-f5w6fw6q 3590 1 These these DT cord-006870-f5w6fw6q 3590 2 articles article NNS cord-006870-f5w6fw6q 3590 3 were be VBD cord-006870-f5w6fw6q 3590 4 chosen choose VBN cord-006870-f5w6fw6q 3590 5 based base VBN cord-006870-f5w6fw6q 3590 6 on on IN cord-006870-f5w6fw6q 3590 7 their -PRON- PRP$ cord-006870-f5w6fw6q 3590 8 overall overall JJ cord-006870-f5w6fw6q 3590 9 importance importance NN cord-006870-f5w6fw6q 3590 10 and and CC cord-006870-f5w6fw6q 3590 11 the the DT cord-006870-f5w6fw6q 3590 12 interest interest NN cord-006870-f5w6fw6q 3590 13 bound bind VBN cord-006870-f5w6fw6q 3590 14 to to TO cord-006870-f5w6fw6q 3590 15 generate generate VB cord-006870-f5w6fw6q 3590 16 amongst amongst IN cord-006870-f5w6fw6q 3590 17 the the DT cord-006870-f5w6fw6q 3590 18 journal journal NN cord-006870-f5w6fw6q 3590 19 club club NN cord-006870-f5w6fw6q 3590 20 attendees attendee NNS cord-006870-f5w6fw6q 3590 21 . . . cord-006870-f5w6fw6q 3591 1 The the DT cord-006870-f5w6fw6q 3591 2 journal journal NN cord-006870-f5w6fw6q 3591 3 club club NN cord-006870-f5w6fw6q 3591 4 occurs occur VBZ cord-006870-f5w6fw6q 3591 5 bimonthy bimonthy NNP cord-006870-f5w6fw6q 3591 6 over over IN cord-006870-f5w6fw6q 3591 7 an an DT cord-006870-f5w6fw6q 3591 8 hour hour NN cord-006870-f5w6fw6q 3591 9 and and CC cord-006870-f5w6fw6q 3591 10 is be VBZ cord-006870-f5w6fw6q 3591 11 unique unique JJ cord-006870-f5w6fw6q 3591 12 in in IN cord-006870-f5w6fw6q 3591 13 the the DT cord-006870-f5w6fw6q 3591 14 participation participation NN cord-006870-f5w6fw6q 3591 15 of of IN cord-006870-f5w6fw6q 3591 16 the the DT cord-006870-f5w6fw6q 3591 17 authors author NNS cord-006870-f5w6fw6q 3591 18 . . . cord-006870-f5w6fw6q 3592 1 The the DT cord-006870-f5w6fw6q 3592 2 journal journal NN cord-006870-f5w6fw6q 3592 3 club club NN cord-006870-f5w6fw6q 3592 4 is be VBZ cord-006870-f5w6fw6q 3592 5 registered register VBN cord-006870-f5w6fw6q 3592 6 with with IN cord-006870-f5w6fw6q 3592 7 Healthcare Healthcare NNP cord-006870-f5w6fw6q 3592 8 Hashtag Hashtag NNP cord-006870-f5w6fw6q 3592 9 Project Project NNP cord-006870-f5w6fw6q 3592 10 . . . cord-006870-f5w6fw6q 3593 1 Each each DT cord-006870-f5w6fw6q 3593 2 article article NN cord-006870-f5w6fw6q 3593 3 chosen choose VBN cord-006870-f5w6fw6q 3593 4 for for IN cord-006870-f5w6fw6q 3593 5 # # $ cord-006870-f5w6fw6q 3593 6 NCSTJC NCSTJC NNP cord-006870-f5w6fw6q 3593 7 is be VBZ cord-006870-f5w6fw6q 3593 8 made make VBN cord-006870-f5w6fw6q 3593 9 available available JJ cord-006870-f5w6fw6q 3593 10 free free JJ cord-006870-f5w6fw6q 3593 11 to to TO cord-006870-f5w6fw6q 3593 12 download download VB cord-006870-f5w6fw6q 3593 13 2 2 CD cord-006870-f5w6fw6q 3593 14 weeks week NNS cord-006870-f5w6fw6q 3593 15 before before IN cord-006870-f5w6fw6q 3593 16 and and CC cord-006870-f5w6fw6q 3593 17 after after IN cord-006870-f5w6fw6q 3593 18 the the DT cord-006870-f5w6fw6q 3593 19 scheduled schedule VBN cord-006870-f5w6fw6q 3593 20 date date NN cord-006870-f5w6fw6q 3593 21 for for IN cord-006870-f5w6fw6q 3593 22 the the DT cord-006870-f5w6fw6q 3593 23 journal journal NNP cord-006870-f5w6fw6q 3593 24 club club NN cord-006870-f5w6fw6q 3593 25 courts court NNS cord-006870-f5w6fw6q 3593 26 Springer Springer NNP cord-006870-f5w6fw6q 3593 27 . . . cord-006870-f5w6fw6q 3594 1 Analytics Analytics NNP cord-006870-f5w6fw6q 3594 2 data datum NNS cord-006870-f5w6fw6q 3594 3 on on IN cord-006870-f5w6fw6q 3594 4 usage usage NN cord-006870-f5w6fw6q 3594 5 on on IN cord-006870-f5w6fw6q 3594 6 article article NN cord-006870-f5w6fw6q 3594 7 discussed discuss VBN cord-006870-f5w6fw6q 3594 8 in in IN cord-006870-f5w6fw6q 3594 9 # # $ cord-006870-f5w6fw6q 3594 10 NCSTJC NCSTJC NNP cord-006870-f5w6fw6q 3594 11 was be VBD cord-006870-f5w6fw6q 3594 12 obtained obtain VBN cord-006870-f5w6fw6q 3594 13 from from IN cord-006870-f5w6fw6q 3594 14 Sean Sean NNP cord-006870-f5w6fw6q 3594 15 Beppler Beppler NNP cord-006870-f5w6fw6q 3594 16 , , , cord-006870-f5w6fw6q 3594 17 Editor Editor NNP cord-006870-f5w6fw6q 3594 18 , , , cord-006870-f5w6fw6q 3594 19 Clinical Clinical NNP cord-006870-f5w6fw6q 3594 20 Medicine Medicine NNP cord-006870-f5w6fw6q 3594 21 . . . cord-006870-f5w6fw6q 3595 1 Between between IN cord-006870-f5w6fw6q 3595 2 Feb Feb NNP cord-006870-f5w6fw6q 3595 3 2015 2015 CD cord-006870-f5w6fw6q 3595 4 and and CC cord-006870-f5w6fw6q 3595 5 Apr Apr NNP cord-006870-f5w6fw6q 3595 6 2017 2017 CD cord-006870-f5w6fw6q 3595 7 , , , cord-006870-f5w6fw6q 3595 8 12 12 CD cord-006870-f5w6fw6q 3595 9 sessions session NNS cord-006870-f5w6fw6q 3595 10 were be VBD cord-006870-f5w6fw6q 3595 11 held hold VBN cord-006870-f5w6fw6q 3595 12 with with IN cord-006870-f5w6fw6q 3595 13 data datum NNS cord-006870-f5w6fw6q 3595 14 available available JJ cord-006870-f5w6fw6q 3595 15 from from IN cord-006870-f5w6fw6q 3595 16 11 11 CD cord-006870-f5w6fw6q 3595 17 . . . cord-006870-f5w6fw6q 3596 1 The the DT cord-006870-f5w6fw6q 3596 2 NCC NCC NNP cord-006870-f5w6fw6q 3596 3 articles article NNS cord-006870-f5w6fw6q 3596 4 discussed discuss VBD cord-006870-f5w6fw6q 3596 5 had have VBD cord-006870-f5w6fw6q 3596 6 higher high JJR cord-006870-f5w6fw6q 3596 7 than than IN cord-006870-f5w6fw6q 3596 8 average average JJ cord-006870-f5w6fw6q 3596 9 Altmetric Altmetric NNP cord-006870-f5w6fw6q 3596 10 scores score NNS cord-006870-f5w6fw6q 3596 11 ( ( -LRB- cord-006870-f5w6fw6q 3596 12 measuring measure VBG cord-006870-f5w6fw6q 3596 13 social social JJ cord-006870-f5w6fw6q 3596 14 media medium NNS cord-006870-f5w6fw6q 3596 15 activity activity NN cord-006870-f5w6fw6q 3596 16 ) ) -RRB- cord-006870-f5w6fw6q 3596 17 . . . cord-006870-f5w6fw6q 3597 1 These these DT cord-006870-f5w6fw6q 3597 2 articles article NNS cord-006870-f5w6fw6q 3597 3 represented represent VBD cord-006870-f5w6fw6q 3597 4 5 5 CD cord-006870-f5w6fw6q 3597 5 % % NN cord-006870-f5w6fw6q 3597 6 of of IN cord-006870-f5w6fw6q 3597 7 all all DT cord-006870-f5w6fw6q 3597 8 NCC NCC NNP cord-006870-f5w6fw6q 3597 9 articles article NNS cord-006870-f5w6fw6q 3597 10 discussed discuss VBN cord-006870-f5w6fw6q 3597 11 on on IN cord-006870-f5w6fw6q 3597 12 Twitter Twitter NNP cord-006870-f5w6fw6q 3597 13 since since IN cord-006870-f5w6fw6q 3597 14 Feb Feb NNP cord-006870-f5w6fw6q 3597 15 2015 2015 CD cord-006870-f5w6fw6q 3597 16 but but CC cord-006870-f5w6fw6q 3597 17 15.3 15.3 CD cord-006870-f5w6fw6q 3597 18 % % NN cord-006870-f5w6fw6q 3597 19 of of IN cord-006870-f5w6fw6q 3597 20 all all DT cord-006870-f5w6fw6q 3597 21 tweets tweet NNS cord-006870-f5w6fw6q 3597 22 . . . cord-006870-f5w6fw6q 3598 1 Total total JJ cord-006870-f5w6fw6q 3598 2 Usage usage NN cord-006870-f5w6fw6q 3598 3 ( ( -LRB- cord-006870-f5w6fw6q 3598 4 number number NN cord-006870-f5w6fw6q 3598 5 of of IN cord-006870-f5w6fw6q 3598 6 times time NNS cord-006870-f5w6fw6q 3598 7 an an DT cord-006870-f5w6fw6q 3598 8 article article NN cord-006870-f5w6fw6q 3598 9 HTML html NN cord-006870-f5w6fw6q 3598 10 page page NN cord-006870-f5w6fw6q 3598 11 is be VBZ cord-006870-f5w6fw6q 3598 12 accessed access VBN cord-006870-f5w6fw6q 3598 13 , , , cord-006870-f5w6fw6q 3598 14 or or CC cord-006870-f5w6fw6q 3598 15 a a DT cord-006870-f5w6fw6q 3598 16 pdf pdf NN cord-006870-f5w6fw6q 3598 17 is be VBZ cord-006870-f5w6fw6q 3598 18 downloaded download VBN cord-006870-f5w6fw6q 3598 19 ) ) -RRB- cord-006870-f5w6fw6q 3598 20 was be VBD cord-006870-f5w6fw6q 3598 21 12 12 CD cord-006870-f5w6fw6q 3598 22 , , , cord-006870-f5w6fw6q 3598 23 989 989 CD cord-006870-f5w6fw6q 3599 1 ( ( -LRB- cord-006870-f5w6fw6q 3599 2 Mean mean JJ cord-006870-f5w6fw6q 3599 3 1082 1082 CD cord-006870-f5w6fw6q 3599 4 , , , cord-006870-f5w6fw6q 3599 5 n=11 n=11 NNP cord-006870-f5w6fw6q 3599 6 ) ) -RRB- cord-006870-f5w6fw6q 3599 7 representing represent VBG cord-006870-f5w6fw6q 3599 8 24.6 24.6 CD cord-006870-f5w6fw6q 3599 9 % % NN cord-006870-f5w6fw6q 3599 10 usage usage NN cord-006870-f5w6fw6q 3599 11 of of IN cord-006870-f5w6fw6q 3599 12 all all DT cord-006870-f5w6fw6q 3599 13 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3599 14 care care NN cord-006870-f5w6fw6q 3599 15 articles article NNS cord-006870-f5w6fw6q 3599 16 , , , cord-006870-f5w6fw6q 3599 17 a a DT cord-006870-f5w6fw6q 3599 18 total total NN cord-006870-f5w6fw6q 3599 19 of of IN cord-006870-f5w6fw6q 3599 20 39 39 CD cord-006870-f5w6fw6q 3599 21 citations citation NNS cord-006870-f5w6fw6q 3599 22 and and CC cord-006870-f5w6fw6q 3599 23 3191 3191 CD cord-006870-f5w6fw6q 3599 24 downloads download NNS cord-006870-f5w6fw6q 3599 25 ( ( -LRB- cord-006870-f5w6fw6q 3599 26 mean mean VB cord-006870-f5w6fw6q 3599 27 290 290 CD cord-006870-f5w6fw6q 3599 28 ) ) -RRB- cord-006870-f5w6fw6q 3599 29 . . . cord-006870-f5w6fw6q 3600 1 The the DT cord-006870-f5w6fw6q 3600 2 upper upper JJ cord-006870-f5w6fw6q 3600 3 bound bind VBN cord-006870-f5w6fw6q 3600 4 of of IN cord-006870-f5w6fw6q 3600 5 the the DT cord-006870-f5w6fw6q 3600 6 audience audience NN cord-006870-f5w6fw6q 3600 7 as as IN cord-006870-f5w6fw6q 3600 8 assessed assess VBN cord-006870-f5w6fw6q 3600 9 by by IN cord-006870-f5w6fw6q 3600 10 the the DT cord-006870-f5w6fw6q 3600 11 publisher publisher NN cord-006870-f5w6fw6q 3600 12 was be VBD cord-006870-f5w6fw6q 3600 13 total total NN cord-006870-f5w6fw6q 3600 14 of of IN cord-006870-f5w6fw6q 3600 15 111 111 CD cord-006870-f5w6fw6q 3600 16 , , , cord-006870-f5w6fw6q 3600 17 524 524 CD cord-006870-f5w6fw6q 3600 18 for for IN cord-006870-f5w6fw6q 3600 19 all all DT cord-006870-f5w6fw6q 3600 20 1 1 CD cord-006870-f5w6fw6q 3600 21 articles article NNS cord-006870-f5w6fw6q 3600 22 ( ( -LRB- cord-006870-f5w6fw6q 3600 23 mean mean VB cord-006870-f5w6fw6q 3600 24 9,294 9,294 CD cord-006870-f5w6fw6q 3600 25 per per IN cord-006870-f5w6fw6q 3600 26 article article NN cord-006870-f5w6fw6q 3600 27 ) ) -RRB- cord-006870-f5w6fw6q 3601 1 Twitter Twitter NNP cord-006870-f5w6fw6q 3601 2 is be VBZ cord-006870-f5w6fw6q 3601 3 becoming become VBG cord-006870-f5w6fw6q 3601 4 an an DT cord-006870-f5w6fw6q 3601 5 emerging emerge VBG cord-006870-f5w6fw6q 3601 6 platform platform NN cord-006870-f5w6fw6q 3601 7 for for IN cord-006870-f5w6fw6q 3601 8 dissemination dissemination NN cord-006870-f5w6fw6q 3601 9 of of IN cord-006870-f5w6fw6q 3601 10 information information NN cord-006870-f5w6fw6q 3601 11 in in IN cord-006870-f5w6fw6q 3601 12 medical medical JJ cord-006870-f5w6fw6q 3601 13 education education NN cord-006870-f5w6fw6q 3601 14 and and CC cord-006870-f5w6fw6q 3601 15 academic academic JJ cord-006870-f5w6fw6q 3601 16 activities activity NNS cord-006870-f5w6fw6q 3601 17 . . . cord-006870-f5w6fw6q 3602 1 While while IN cord-006870-f5w6fw6q 3602 2 the the DT cord-006870-f5w6fw6q 3602 3 exact exact JJ cord-006870-f5w6fw6q 3602 4 impact impact NN cord-006870-f5w6fw6q 3602 5 of of IN cord-006870-f5w6fw6q 3602 6 the the DT cord-006870-f5w6fw6q 3602 7 initiative initiative NN cord-006870-f5w6fw6q 3602 8 on on IN cord-006870-f5w6fw6q 3602 9 member member NN cord-006870-f5w6fw6q 3602 10 engagement engagement NN cord-006870-f5w6fw6q 3602 11 or or CC cord-006870-f5w6fw6q 3602 12 outreach outreach NN cord-006870-f5w6fw6q 3602 13 in in IN cord-006870-f5w6fw6q 3602 14 enhancing enhance VBG cord-006870-f5w6fw6q 3602 15 journal journal NN cord-006870-f5w6fw6q 3602 16 impact impact NN cord-006870-f5w6fw6q 3602 17 or or CC cord-006870-f5w6fw6q 3602 18 citations citation NNS cord-006870-f5w6fw6q 3602 19 is be VBZ cord-006870-f5w6fw6q 3602 20 hard hard JJ cord-006870-f5w6fw6q 3602 21 to to TO cord-006870-f5w6fw6q 3602 22 determine determine VB cord-006870-f5w6fw6q 3602 23 , , , cord-006870-f5w6fw6q 3602 24 we -PRON- PRP cord-006870-f5w6fw6q 3602 25 saw see VBD cord-006870-f5w6fw6q 3602 26 trends trend NNS cord-006870-f5w6fw6q 3602 27 in in IN cord-006870-f5w6fw6q 3602 28 enhanced enhance VBN cord-006870-f5w6fw6q 3602 29 engagement engagement NN cord-006870-f5w6fw6q 3602 30 . . . cord-006870-f5w6fw6q 3603 1 Neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3603 2 medications medication NNS cord-006870-f5w6fw6q 3603 3 have have VBP cord-006870-f5w6fw6q 3603 4 been be VBN cord-006870-f5w6fw6q 3603 5 studied study VBN cord-006870-f5w6fw6q 3603 6 in in IN cord-006870-f5w6fw6q 3603 7 patients patient NNS cord-006870-f5w6fw6q 3603 8 with with IN cord-006870-f5w6fw6q 3603 9 traumatic traumatic JJ cord-006870-f5w6fw6q 3603 10 brain brain NN cord-006870-f5w6fw6q 3603 11 injury injury NN cord-006870-f5w6fw6q 3603 12 , , , cord-006870-f5w6fw6q 3603 13 but but CC cord-006870-f5w6fw6q 3603 14 few few JJ cord-006870-f5w6fw6q 3603 15 studies study NNS cord-006870-f5w6fw6q 3603 16 describe describe VBP cord-006870-f5w6fw6q 3603 17 their -PRON- PRP$ cord-006870-f5w6fw6q 3603 18 use use NN cord-006870-f5w6fw6q 3603 19 in in IN cord-006870-f5w6fw6q 3603 20 patients patient NNS cord-006870-f5w6fw6q 3603 21 with with IN cord-006870-f5w6fw6q 3603 22 acute acute JJ cord-006870-f5w6fw6q 3603 23 non non JJ cord-006870-f5w6fw6q 3603 24 - - JJ cord-006870-f5w6fw6q 3603 25 traumatic traumatic JJ cord-006870-f5w6fw6q 3603 26 brain brain NN cord-006870-f5w6fw6q 3603 27 injury injury NN cord-006870-f5w6fw6q 3603 28 . . . cord-006870-f5w6fw6q 3604 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3604 2 objective objective NN cord-006870-f5w6fw6q 3604 3 was be VBD cord-006870-f5w6fw6q 3604 4 to to TO cord-006870-f5w6fw6q 3604 5 describe describe VB cord-006870-f5w6fw6q 3604 6 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3604 7 medication medication NN cord-006870-f5w6fw6q 3604 8 prescribing prescribe VBG cord-006870-f5w6fw6q 3604 9 patterns pattern NNS cord-006870-f5w6fw6q 3604 10 , , , cord-006870-f5w6fw6q 3604 11 clinical clinical JJ cord-006870-f5w6fw6q 3604 12 response response NN cord-006870-f5w6fw6q 3604 13 , , , cord-006870-f5w6fw6q 3604 14 and and CC cord-006870-f5w6fw6q 3604 15 potential potential JJ cord-006870-f5w6fw6q 3604 16 adverse adverse JJ cord-006870-f5w6fw6q 3604 17 effects effect NNS cord-006870-f5w6fw6q 3604 18 in in IN cord-006870-f5w6fw6q 3604 19 this this DT cord-006870-f5w6fw6q 3604 20 patient patient JJ cord-006870-f5w6fw6q 3604 21 population population NN cord-006870-f5w6fw6q 3604 22 . . . cord-006870-f5w6fw6q 3605 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 3605 2 database database NN cord-006870-f5w6fw6q 3605 3 review review NN cord-006870-f5w6fw6q 3605 4 of of IN cord-006870-f5w6fw6q 3605 5 patients patient NNS cord-006870-f5w6fw6q 3605 6 with with IN cord-006870-f5w6fw6q 3605 7 acute acute JJ cord-006870-f5w6fw6q 3605 8 ischemic ischemic JJ cord-006870-f5w6fw6q 3605 9 stroke stroke NN cord-006870-f5w6fw6q 3605 10 , , , cord-006870-f5w6fw6q 3605 11 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3605 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3605 13 , , , cord-006870-f5w6fw6q 3605 14 or or CC cord-006870-f5w6fw6q 3605 15 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3605 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3605 17 who who WP cord-006870-f5w6fw6q 3605 18 received receive VBD cord-006870-f5w6fw6q 3605 19 amantadine amantadine NNP cord-006870-f5w6fw6q 3605 20 or or CC cord-006870-f5w6fw6q 3605 21 modafinil modafinil NN cord-006870-f5w6fw6q 3605 22 from from IN cord-006870-f5w6fw6q 3605 23 December December NNP cord-006870-f5w6fw6q 3605 24 2012 2012 CD cord-006870-f5w6fw6q 3605 25 through through IN cord-006870-f5w6fw6q 3605 26 June June NNP cord-006870-f5w6fw6q 3605 27 2016 2016 CD cord-006870-f5w6fw6q 3605 28 . . . cord-006870-f5w6fw6q 3606 1 Neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3606 2 selection selection NN cord-006870-f5w6fw6q 3606 3 , , , cord-006870-f5w6fw6q 3606 4 dosing dose VBG cord-006870-f5w6fw6q 3606 5 regimen regimen NN cord-006870-f5w6fw6q 3606 6 , , , cord-006870-f5w6fw6q 3606 7 and and CC cord-006870-f5w6fw6q 3606 8 indication indication NN cord-006870-f5w6fw6q 3606 9 were be VBD cord-006870-f5w6fw6q 3606 10 recorded record VBN cord-006870-f5w6fw6q 3606 11 . . . cord-006870-f5w6fw6q 3607 1 Patients patient NNS cord-006870-f5w6fw6q 3607 2 were be VBD cord-006870-f5w6fw6q 3607 3 classified classify VBN cord-006870-f5w6fw6q 3607 4 as as IN cord-006870-f5w6fw6q 3607 5 responders responder NNS cord-006870-f5w6fw6q 3607 6 if if IN cord-006870-f5w6fw6q 3607 7 they -PRON- PRP cord-006870-f5w6fw6q 3607 8 met meet VBD cord-006870-f5w6fw6q 3607 9 two two CD cord-006870-f5w6fw6q 3607 10 of of IN cord-006870-f5w6fw6q 3607 11 the the DT cord-006870-f5w6fw6q 3607 12 following following JJ cord-006870-f5w6fw6q 3607 13 three three CD cord-006870-f5w6fw6q 3607 14 criteria criterion NNS cord-006870-f5w6fw6q 3607 15 within within IN cord-006870-f5w6fw6q 3607 16 7 7 CD cord-006870-f5w6fw6q 3607 17 days day NNS cord-006870-f5w6fw6q 3607 18 of of IN cord-006870-f5w6fw6q 3607 19 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3607 20 initiation initiation NN cord-006870-f5w6fw6q 3607 21 : : : cord-006870-f5w6fw6q 3607 22 1 1 LS cord-006870-f5w6fw6q 3607 23 ) ) -RRB- cord-006870-f5w6fw6q 3607 24 increase increase NN cord-006870-f5w6fw6q 3607 25 in in IN cord-006870-f5w6fw6q 3607 26 average average JJ cord-006870-f5w6fw6q 3607 27 daily daily JJ cord-006870-f5w6fw6q 3607 28 GCS GCS NNP cord-006870-f5w6fw6q 3607 29 of of IN cord-006870-f5w6fw6q 3607 30 greater great JJR cord-006870-f5w6fw6q 3607 31 than than IN cord-006870-f5w6fw6q 3607 32 3 3 CD cord-006870-f5w6fw6q 3607 33 points point NNS cord-006870-f5w6fw6q 3607 34 , , , cord-006870-f5w6fw6q 3607 35 2 2 CD cord-006870-f5w6fw6q 3607 36 ) ) -RRB- cord-006870-f5w6fw6q 3608 1 neurological neurological JJ cord-006870-f5w6fw6q 3608 2 improvement improvement NN cord-006870-f5w6fw6q 3608 3 documented document VBN cord-006870-f5w6fw6q 3608 4 in in IN cord-006870-f5w6fw6q 3608 5 provider provider NN cord-006870-f5w6fw6q 3608 6 progress progress NN cord-006870-f5w6fw6q 3608 7 notes note NNS cord-006870-f5w6fw6q 3608 8 , , , cord-006870-f5w6fw6q 3608 9 or or CC cord-006870-f5w6fw6q 3608 10 3 3 LS cord-006870-f5w6fw6q 3608 11 ) ) -RRB- cord-006870-f5w6fw6q 3608 12 increased increase VBN cord-006870-f5w6fw6q 3608 13 participation participation NN cord-006870-f5w6fw6q 3608 14 in in IN cord-006870-f5w6fw6q 3608 15 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 3608 16 therapies therapy NNS cord-006870-f5w6fw6q 3608 17 documented document VBN cord-006870-f5w6fw6q 3608 18 in in IN cord-006870-f5w6fw6q 3608 19 physical physical JJ cord-006870-f5w6fw6q 3608 20 or or CC cord-006870-f5w6fw6q 3608 21 occupational occupational JJ cord-006870-f5w6fw6q 3608 22 therapist therapist NN cord-006870-f5w6fw6q 3608 23 progress progress NN cord-006870-f5w6fw6q 3608 24 notes note NNS cord-006870-f5w6fw6q 3608 25 . . . cord-006870-f5w6fw6q 3609 1 Safety safety NN cord-006870-f5w6fw6q 3609 2 data datum NNS cord-006870-f5w6fw6q 3609 3 included include VBD cord-006870-f5w6fw6q 3609 4 need need NN cord-006870-f5w6fw6q 3609 5 for for IN cord-006870-f5w6fw6q 3609 6 a a DT cord-006870-f5w6fw6q 3609 7 new new JJ cord-006870-f5w6fw6q 3609 8 anxiolytic anxiolytic JJ cord-006870-f5w6fw6q 3609 9 or or CC cord-006870-f5w6fw6q 3609 10 sleep sleep VB cord-006870-f5w6fw6q 3609 11 aid aid NN cord-006870-f5w6fw6q 3609 12 or or CC cord-006870-f5w6fw6q 3609 13 seizure seizure NN cord-006870-f5w6fw6q 3609 14 . . . cord-006870-f5w6fw6q 3610 1 Continuous continuous JJ cord-006870-f5w6fw6q 3610 2 data datum NNS cord-006870-f5w6fw6q 3610 3 are be VBP cord-006870-f5w6fw6q 3610 4 reported report VBN cord-006870-f5w6fw6q 3610 5 as as IN cord-006870-f5w6fw6q 3610 6 median median NN cord-006870-f5w6fw6q 3610 7 with with IN cord-006870-f5w6fw6q 3610 8 interquartile interquartile JJ cord-006870-f5w6fw6q 3610 9 range range NN cord-006870-f5w6fw6q 3610 10 . . . cord-006870-f5w6fw6q 3611 1 Eighty eighty CD cord-006870-f5w6fw6q 3611 2 - - HYPH cord-006870-f5w6fw6q 3611 3 eight eight CD cord-006870-f5w6fw6q 3611 4 patients patient NNS cord-006870-f5w6fw6q 3611 5 received receive VBD cord-006870-f5w6fw6q 3611 6 neurostimulants neurostimulant NNS cord-006870-f5w6fw6q 3611 7 : : : cord-006870-f5w6fw6q 3611 8 intracerebral intracerebral NNP cord-006870-f5w6fw6q 3611 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3611 10 ( ( -LRB- cord-006870-f5w6fw6q 3611 11 n=41 n=41 RB cord-006870-f5w6fw6q 3611 12 ) ) -RRB- cord-006870-f5w6fw6q 3611 13 , , , cord-006870-f5w6fw6q 3611 14 ischemic ischemic JJ cord-006870-f5w6fw6q 3611 15 stroke stroke NN cord-006870-f5w6fw6q 3611 16 ( ( -LRB- cord-006870-f5w6fw6q 3611 17 n=30 n=30 NNP cord-006870-f5w6fw6q 3611 18 ) ) -RRB- cord-006870-f5w6fw6q 3611 19 , , , cord-006870-f5w6fw6q 3611 20 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3611 21 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3611 22 ( ( -LRB- cord-006870-f5w6fw6q 3611 23 n=17 n=17 NNP cord-006870-f5w6fw6q 3611 24 ) ) -RRB- cord-006870-f5w6fw6q 3611 25 . . . cord-006870-f5w6fw6q 3612 1 Median median JJ cord-006870-f5w6fw6q 3612 2 age age NN cord-006870-f5w6fw6q 3612 3 was be VBD cord-006870-f5w6fw6q 3612 4 66 66 CD cord-006870-f5w6fw6q 3613 1 ( ( -LRB- cord-006870-f5w6fw6q 3613 2 55 55 CD cord-006870-f5w6fw6q 3613 3 - - SYM cord-006870-f5w6fw6q 3613 4 73 73 CD cord-006870-f5w6fw6q 3613 5 ) ) -RRB- cord-006870-f5w6fw6q 3613 6 years year NNS cord-006870-f5w6fw6q 3613 7 and and CC cord-006870-f5w6fw6q 3613 8 57 57 CD cord-006870-f5w6fw6q 3613 9 ( ( -LRB- cord-006870-f5w6fw6q 3613 10 65 65 CD cord-006870-f5w6fw6q 3613 11 % % NN cord-006870-f5w6fw6q 3613 12 ) ) -RRB- cord-006870-f5w6fw6q 3613 13 were be VBD cord-006870-f5w6fw6q 3613 14 male male JJ cord-006870-f5w6fw6q 3613 15 . . . cord-006870-f5w6fw6q 3614 1 Amantadine Amantadine NNP cord-006870-f5w6fw6q 3614 2 ( ( -LRB- cord-006870-f5w6fw6q 3614 3 n=71 n=71 NN cord-006870-f5w6fw6q 3614 4 ) ) -RRB- cord-006870-f5w6fw6q 3614 5 , , , cord-006870-f5w6fw6q 3614 6 modafinil modafinil NN cord-006870-f5w6fw6q 3614 7 ( ( -LRB- cord-006870-f5w6fw6q 3614 8 n=13 n=13 NNP cord-006870-f5w6fw6q 3614 9 ) ) -RRB- cord-006870-f5w6fw6q 3614 10 , , , cord-006870-f5w6fw6q 3614 11 or or CC cord-006870-f5w6fw6q 3614 12 both both DT cord-006870-f5w6fw6q 3614 13 ( ( -LRB- cord-006870-f5w6fw6q 3614 14 n=4 n=4 NNS cord-006870-f5w6fw6q 3614 15 ) ) -RRB- cord-006870-f5w6fw6q 3614 16 were be VBD cord-006870-f5w6fw6q 3614 17 initiated initiate VBN cord-006870-f5w6fw6q 3614 18 a a DT cord-006870-f5w6fw6q 3614 19 median median NN cord-006870-f5w6fw6q 3614 20 of of IN cord-006870-f5w6fw6q 3614 21 7 7 CD cord-006870-f5w6fw6q 3614 22 ( ( -LRB- cord-006870-f5w6fw6q 3614 23 5 5 CD cord-006870-f5w6fw6q 3614 24 - - SYM cord-006870-f5w6fw6q 3614 25 13 13 CD cord-006870-f5w6fw6q 3614 26 ) ) -RRB- cord-006870-f5w6fw6q 3614 27 days day NNS cord-006870-f5w6fw6q 3614 28 after after IN cord-006870-f5w6fw6q 3614 29 hospital hospital NN cord-006870-f5w6fw6q 3614 30 admission admission NN cord-006870-f5w6fw6q 3614 31 . . . cord-006870-f5w6fw6q 3615 1 The the DT cord-006870-f5w6fw6q 3615 2 median median JJ cord-006870-f5w6fw6q 3615 3 initial initial JJ cord-006870-f5w6fw6q 3615 4 daily daily JJ cord-006870-f5w6fw6q 3615 5 dose dose NN cord-006870-f5w6fw6q 3615 6 of of IN cord-006870-f5w6fw6q 3615 7 amantadine amantadine NNP cord-006870-f5w6fw6q 3615 8 and and CC cord-006870-f5w6fw6q 3615 9 modafinil modafinil NN cord-006870-f5w6fw6q 3615 10 were be VBD cord-006870-f5w6fw6q 3615 11 200 200 CD cord-006870-f5w6fw6q 3615 12 mg mg NN cord-006870-f5w6fw6q 3615 13 and and CC cord-006870-f5w6fw6q 3615 14 100 100 CD cord-006870-f5w6fw6q 3615 15 mg mg NNS cord-006870-f5w6fw6q 3615 16 , , , cord-006870-f5w6fw6q 3615 17 respectively respectively RB cord-006870-f5w6fw6q 3615 18 . . . cord-006870-f5w6fw6q 3616 1 Reasons reason NNS cord-006870-f5w6fw6q 3616 2 for for IN cord-006870-f5w6fw6q 3616 3 initiation initiation NN cord-006870-f5w6fw6q 3616 4 included include VBD cord-006870-f5w6fw6q 3616 5 somnolence somnolence NN cord-006870-f5w6fw6q 3616 6 ( ( -LRB- cord-006870-f5w6fw6q 3616 7 77 77 CD cord-006870-f5w6fw6q 3616 8 % % NN cord-006870-f5w6fw6q 3616 9 ) ) -RRB- cord-006870-f5w6fw6q 3616 10 , , , cord-006870-f5w6fw6q 3616 11 not not RB cord-006870-f5w6fw6q 3616 12 following follow VBG cord-006870-f5w6fw6q 3616 13 commands command NNS cord-006870-f5w6fw6q 3616 14 ( ( -LRB- cord-006870-f5w6fw6q 3616 15 31 31 CD cord-006870-f5w6fw6q 3616 16 % % NN cord-006870-f5w6fw6q 3616 17 ) ) -RRB- cord-006870-f5w6fw6q 3616 18 , , , cord-006870-f5w6fw6q 3616 19 lack lack NN cord-006870-f5w6fw6q 3616 20 of of IN cord-006870-f5w6fw6q 3616 21 eye eye NN cord-006870-f5w6fw6q 3616 22 opening opening NN cord-006870-f5w6fw6q 3616 23 ( ( -LRB- cord-006870-f5w6fw6q 3616 24 28 28 CD cord-006870-f5w6fw6q 3616 25 % % NN cord-006870-f5w6fw6q 3616 26 ) ) -RRB- cord-006870-f5w6fw6q 3616 27 , , , cord-006870-f5w6fw6q 3616 28 and and CC cord-006870-f5w6fw6q 3616 29 low low JJ cord-006870-f5w6fw6q 3616 30 GCS GCS NNP cord-006870-f5w6fw6q 3616 31 ( ( -LRB- cord-006870-f5w6fw6q 3616 32 17 17 CD cord-006870-f5w6fw6q 3616 33 % % NN cord-006870-f5w6fw6q 3616 34 ) ) -RRB- cord-006870-f5w6fw6q 3616 35 . . . cord-006870-f5w6fw6q 3617 1 Forty forty CD cord-006870-f5w6fw6q 3617 2 ( ( -LRB- cord-006870-f5w6fw6q 3617 3 45 45 CD cord-006870-f5w6fw6q 3617 4 % % NN cord-006870-f5w6fw6q 3617 5 ) ) -RRB- cord-006870-f5w6fw6q 3617 6 patients patient NNS cord-006870-f5w6fw6q 3617 7 were be VBD cord-006870-f5w6fw6q 3617 8 responders responder NNS cord-006870-f5w6fw6q 3617 9 , , , cord-006870-f5w6fw6q 3617 10 occurring occur VBG cord-006870-f5w6fw6q 3617 11 at at IN cord-006870-f5w6fw6q 3617 12 a a DT cord-006870-f5w6fw6q 3617 13 median median NN cord-006870-f5w6fw6q 3617 14 of of IN cord-006870-f5w6fw6q 3617 15 3 3 CD cord-006870-f5w6fw6q 3617 16 ( ( -LRB- cord-006870-f5w6fw6q 3617 17 2 2 CD cord-006870-f5w6fw6q 3617 18 - - SYM cord-006870-f5w6fw6q 3617 19 5 5 CD cord-006870-f5w6fw6q 3617 20 ) ) -RRB- cord-006870-f5w6fw6q 3617 21 days day NNS cord-006870-f5w6fw6q 3617 22 after after IN cord-006870-f5w6fw6q 3617 23 neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3617 24 initiation initiation NN cord-006870-f5w6fw6q 3617 25 . . . cord-006870-f5w6fw6q 3618 1 Twenty twenty CD cord-006870-f5w6fw6q 3618 2 - - HYPH cord-006870-f5w6fw6q 3618 3 three three CD cord-006870-f5w6fw6q 3618 4 ( ( -LRB- cord-006870-f5w6fw6q 3618 5 26 26 CD cord-006870-f5w6fw6q 3618 6 % % NN cord-006870-f5w6fw6q 3618 7 ) ) -RRB- cord-006870-f5w6fw6q 3618 8 patients patient NNS cord-006870-f5w6fw6q 3618 9 required require VBD cord-006870-f5w6fw6q 3618 10 new new JJ cord-006870-f5w6fw6q 3618 11 prescription prescription NN cord-006870-f5w6fw6q 3618 12 of of IN cord-006870-f5w6fw6q 3618 13 an an DT cord-006870-f5w6fw6q 3618 14 anxiolytic anxiolytic JJ cord-006870-f5w6fw6q 3618 15 or or CC cord-006870-f5w6fw6q 3618 16 sleep sleep NN cord-006870-f5w6fw6q 3618 17 aid aid NN cord-006870-f5w6fw6q 3618 18 . . . cord-006870-f5w6fw6q 3619 1 Four four CD cord-006870-f5w6fw6q 3619 2 ( ( -LRB- cord-006870-f5w6fw6q 3619 3 5 5 CD cord-006870-f5w6fw6q 3619 4 % % NN cord-006870-f5w6fw6q 3619 5 ) ) -RRB- cord-006870-f5w6fw6q 3620 1 patients patient NNS cord-006870-f5w6fw6q 3620 2 developed develop VBD cord-006870-f5w6fw6q 3620 3 seizure seizure NN cord-006870-f5w6fw6q 3620 4 . . . cord-006870-f5w6fw6q 3621 1 Neurostimulant neurostimulant JJ cord-006870-f5w6fw6q 3621 2 medications medication NNS cord-006870-f5w6fw6q 3621 3 may may MD cord-006870-f5w6fw6q 3621 4 increase increase VB cord-006870-f5w6fw6q 3621 5 wakefulness wakefulness NN cord-006870-f5w6fw6q 3621 6 and and CC cord-006870-f5w6fw6q 3621 7 participation participation NN cord-006870-f5w6fw6q 3621 8 in in IN cord-006870-f5w6fw6q 3621 9 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 3621 10 therapies therapy NNS cord-006870-f5w6fw6q 3621 11 in in IN cord-006870-f5w6fw6q 3621 12 patients patient NNS cord-006870-f5w6fw6q 3621 13 with with IN cord-006870-f5w6fw6q 3621 14 acute acute JJ cord-006870-f5w6fw6q 3621 15 non non JJ cord-006870-f5w6fw6q 3621 16 - - JJ cord-006870-f5w6fw6q 3621 17 traumatic traumatic JJ cord-006870-f5w6fw6q 3621 18 brain brain NN cord-006870-f5w6fw6q 3621 19 injury injury NN cord-006870-f5w6fw6q 3621 20 , , , cord-006870-f5w6fw6q 3621 21 with with IN cord-006870-f5w6fw6q 3621 22 tolerable tolerable JJ cord-006870-f5w6fw6q 3621 23 adverse adverse JJ cord-006870-f5w6fw6q 3621 24 effects effect NNS cord-006870-f5w6fw6q 3621 25 . . . cord-006870-f5w6fw6q 3622 1 The the DT cord-006870-f5w6fw6q 3622 2 role role NN cord-006870-f5w6fw6q 3622 3 of of IN cord-006870-f5w6fw6q 3622 4 neurostimulants neurostimulant NNS cord-006870-f5w6fw6q 3622 5 in in IN cord-006870-f5w6fw6q 3622 6 this this DT cord-006870-f5w6fw6q 3622 7 population population NN cord-006870-f5w6fw6q 3622 8 should should MD cord-006870-f5w6fw6q 3622 9 be be VB cord-006870-f5w6fw6q 3622 10 defined define VBN cord-006870-f5w6fw6q 3622 11 in in IN cord-006870-f5w6fw6q 3622 12 prospective prospective JJ cord-006870-f5w6fw6q 3622 13 studies study NNS cord-006870-f5w6fw6q 3622 14 . . . cord-006870-f5w6fw6q 3623 1 Difficulty difficulty NN cord-006870-f5w6fw6q 3623 2 in in IN cord-006870-f5w6fw6q 3623 3 obtaining obtain VBG cord-006870-f5w6fw6q 3623 4 peripheral peripheral JJ cord-006870-f5w6fw6q 3623 5 intravenous intravenous NN cord-006870-f5w6fw6q 3623 6 ( ( -LRB- cord-006870-f5w6fw6q 3623 7 PIV PIV NNP cord-006870-f5w6fw6q 3623 8 ) ) -RRB- cord-006870-f5w6fw6q 3623 9 access access NN cord-006870-f5w6fw6q 3623 10 often often RB cord-006870-f5w6fw6q 3623 11 necessitates necessitate VBZ cord-006870-f5w6fw6q 3623 12 central central JJ cord-006870-f5w6fw6q 3623 13 venous venous JJ cord-006870-f5w6fw6q 3623 14 access access NN cord-006870-f5w6fw6q 3623 15 placement placement NN cord-006870-f5w6fw6q 3623 16 in in IN cord-006870-f5w6fw6q 3623 17 many many JJ cord-006870-f5w6fw6q 3623 18 critically critically RB cord-006870-f5w6fw6q 3623 19 ill ill JJ cord-006870-f5w6fw6q 3623 20 patients patient NNS cord-006870-f5w6fw6q 3623 21 . . . cord-006870-f5w6fw6q 3624 1 Central central JJ cord-006870-f5w6fw6q 3624 2 line line NN cord-006870-f5w6fw6q 3624 3 placement placement NN cord-006870-f5w6fw6q 3624 4 exposes expose VBZ cord-006870-f5w6fw6q 3624 5 patients patient NNS cord-006870-f5w6fw6q 3624 6 to to IN cord-006870-f5w6fw6q 3624 7 potential potential JJ cord-006870-f5w6fw6q 3624 8 complications complication NNS cord-006870-f5w6fw6q 3624 9 such such JJ cord-006870-f5w6fw6q 3624 10 as as IN cord-006870-f5w6fw6q 3624 11 pneumothorax pneumothorax NN cord-006870-f5w6fw6q 3624 12 , , , cord-006870-f5w6fw6q 3624 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3624 14 , , , cord-006870-f5w6fw6q 3624 15 catheter catheter NN cord-006870-f5w6fw6q 3624 16 - - HYPH cord-006870-f5w6fw6q 3624 17 related relate VBN cord-006870-f5w6fw6q 3624 18 infection infection NN cord-006870-f5w6fw6q 3624 19 or or CC cord-006870-f5w6fw6q 3624 20 deep deep JJ cord-006870-f5w6fw6q 3624 21 venous venous JJ cord-006870-f5w6fw6q 3624 22 thrombosis thrombosis NN cord-006870-f5w6fw6q 3624 23 . . . cord-006870-f5w6fw6q 3625 1 Ultrasound ultrasound NN cord-006870-f5w6fw6q 3625 2 - - HYPH cord-006870-f5w6fw6q 3625 3 guided guide VBN cord-006870-f5w6fw6q 3625 4 PIV PIV NNP cord-006870-f5w6fw6q 3625 5 placement placement NN cord-006870-f5w6fw6q 3625 6 has have VBZ cord-006870-f5w6fw6q 3625 7 become become VBN cord-006870-f5w6fw6q 3625 8 common common JJ cord-006870-f5w6fw6q 3625 9 practice practice NN cord-006870-f5w6fw6q 3625 10 in in IN cord-006870-f5w6fw6q 3625 11 emergency emergency NN cord-006870-f5w6fw6q 3625 12 departments department NNS cord-006870-f5w6fw6q 3625 13 , , , cord-006870-f5w6fw6q 3625 14 but but CC cord-006870-f5w6fw6q 3625 15 there there EX cord-006870-f5w6fw6q 3625 16 is be VBZ cord-006870-f5w6fw6q 3625 17 no no DT cord-006870-f5w6fw6q 3625 18 systematic systematic JJ cord-006870-f5w6fw6q 3625 19 program program NN cord-006870-f5w6fw6q 3625 20 to to TO cord-006870-f5w6fw6q 3625 21 train train VB cord-006870-f5w6fw6q 3625 22 and and CC cord-006870-f5w6fw6q 3625 23 support support VB cord-006870-f5w6fw6q 3625 24 routine routine JJ cord-006870-f5w6fw6q 3625 25 use use NN cord-006870-f5w6fw6q 3625 26 of of IN cord-006870-f5w6fw6q 3625 27 ultrasound ultrasound NN cord-006870-f5w6fw6q 3625 28 - - HYPH cord-006870-f5w6fw6q 3625 29 guided guide VBN cord-006870-f5w6fw6q 3625 30 PIV PIV NNP cord-006870-f5w6fw6q 3625 31 access access NN cord-006870-f5w6fw6q 3625 32 in in IN cord-006870-f5w6fw6q 3625 33 ICUs ICUs NNP cord-006870-f5w6fw6q 3625 34 . . . cord-006870-f5w6fw6q 3626 1 We -PRON- PRP cord-006870-f5w6fw6q 3626 2 have have VBP cord-006870-f5w6fw6q 3626 3 developed develop VBN cord-006870-f5w6fw6q 3626 4 a a DT cord-006870-f5w6fw6q 3626 5 systematic systematic JJ cord-006870-f5w6fw6q 3626 6 program program NN cord-006870-f5w6fw6q 3626 7 to to TO cord-006870-f5w6fw6q 3626 8 train train VB cord-006870-f5w6fw6q 3626 9 and and CC cord-006870-f5w6fw6q 3626 10 support support VB cord-006870-f5w6fw6q 3626 11 ICU ICU NNP cord-006870-f5w6fw6q 3626 12 nurses nurse NNS cord-006870-f5w6fw6q 3626 13 in in IN cord-006870-f5w6fw6q 3626 14 becoming become VBG cord-006870-f5w6fw6q 3626 15 experts expert NNS cord-006870-f5w6fw6q 3626 16 and and CC cord-006870-f5w6fw6q 3626 17 clinical clinical JJ cord-006870-f5w6fw6q 3626 18 leaders leader NNS cord-006870-f5w6fw6q 3626 19 in in IN cord-006870-f5w6fw6q 3626 20 ultrasound ultrasound NN cord-006870-f5w6fw6q 3626 21 - - HYPH cord-006870-f5w6fw6q 3626 22 guided guide VBN cord-006870-f5w6fw6q 3626 23 PIV PIV NNP cord-006870-f5w6fw6q 3626 24 placement placement NN cord-006870-f5w6fw6q 3626 25 . . . cord-006870-f5w6fw6q 3627 1 We -PRON- PRP cord-006870-f5w6fw6q 3627 2 hypothesize hypothesize VBP cord-006870-f5w6fw6q 3627 3 that that IN cord-006870-f5w6fw6q 3627 4 implementation implementation NN cord-006870-f5w6fw6q 3627 5 of of IN cord-006870-f5w6fw6q 3627 6 this this DT cord-006870-f5w6fw6q 3627 7 program program NN cord-006870-f5w6fw6q 3627 8 will will MD cord-006870-f5w6fw6q 3627 9 increase increase VB cord-006870-f5w6fw6q 3627 10 nurse nurse NN cord-006870-f5w6fw6q 3627 11 confidence confidence NN cord-006870-f5w6fw6q 3627 12 and and CC cord-006870-f5w6fw6q 3627 13 chances chance NNS cord-006870-f5w6fw6q 3627 14 of of IN cord-006870-f5w6fw6q 3627 15 successful successful JJ cord-006870-f5w6fw6q 3627 16 PIV PIV NNP cord-006870-f5w6fw6q 3627 17 placement placement NN cord-006870-f5w6fw6q 3627 18 subsequently subsequently RB cord-006870-f5w6fw6q 3627 19 decrease decrease VBP cord-006870-f5w6fw6q 3627 20 central central JJ cord-006870-f5w6fw6q 3627 21 line line NN cord-006870-f5w6fw6q 3627 22 - - HYPH cord-006870-f5w6fw6q 3627 23 related relate VBN cord-006870-f5w6fw6q 3627 24 complications complication NNS cord-006870-f5w6fw6q 3627 25 in in IN cord-006870-f5w6fw6q 3627 26 30-bed 30-bed CD cord-006870-f5w6fw6q 3627 27 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3627 28 care care NN cord-006870-f5w6fw6q 3627 29 ICUs ICUs NNP cord-006870-f5w6fw6q 3627 30 . . . cord-006870-f5w6fw6q 3628 1 We -PRON- PRP cord-006870-f5w6fw6q 3628 2 have have VBP cord-006870-f5w6fw6q 3628 3 developed develop VBN cord-006870-f5w6fw6q 3628 4 a a DT cord-006870-f5w6fw6q 3628 5 video video NN cord-006870-f5w6fw6q 3628 6 didactic didactic JJ cord-006870-f5w6fw6q 3628 7 training training NN cord-006870-f5w6fw6q 3628 8 program program NN cord-006870-f5w6fw6q 3628 9 for for IN cord-006870-f5w6fw6q 3628 10 the the DT cord-006870-f5w6fw6q 3628 11 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3628 12 care care NNP cord-006870-f5w6fw6q 3628 13 nursing nursing NN cord-006870-f5w6fw6q 3628 14 staff staff NN cord-006870-f5w6fw6q 3628 15 . . . cord-006870-f5w6fw6q 3629 1 The the DT cord-006870-f5w6fw6q 3629 2 program program NN cord-006870-f5w6fw6q 3629 3 discusses discuss VBZ cord-006870-f5w6fw6q 3629 4 use use NN cord-006870-f5w6fw6q 3629 5 and and CC cord-006870-f5w6fw6q 3629 6 maintenance maintenance NN cord-006870-f5w6fw6q 3629 7 of of IN cord-006870-f5w6fw6q 3629 8 the the DT cord-006870-f5w6fw6q 3629 9 ultrasound ultrasound NN cord-006870-f5w6fw6q 3629 10 machine machine NN cord-006870-f5w6fw6q 3629 11 and and CC cord-006870-f5w6fw6q 3629 12 guided guide VBN cord-006870-f5w6fw6q 3629 13 - - HYPH cord-006870-f5w6fw6q 3629 14 technique technique NN cord-006870-f5w6fw6q 3629 15 for for IN cord-006870-f5w6fw6q 3629 16 PIV PIV NNP cord-006870-f5w6fw6q 3629 17 placement placement NN cord-006870-f5w6fw6q 3629 18 including include VBG cord-006870-f5w6fw6q 3629 19 the the DT cord-006870-f5w6fw6q 3629 20 short short JJ cord-006870-f5w6fw6q 3629 21 - - HYPH cord-006870-f5w6fw6q 3629 22 and and CC cord-006870-f5w6fw6q 3629 23 long long JJ cord-006870-f5w6fw6q 3629 24 - - HYPH cord-006870-f5w6fw6q 3629 25 axis axis NN cord-006870-f5w6fw6q 3629 26 approaches approach NNS cord-006870-f5w6fw6q 3629 27 . . . cord-006870-f5w6fw6q 3630 1 The the DT cord-006870-f5w6fw6q 3630 2 training training NN cord-006870-f5w6fw6q 3630 3 video video NN cord-006870-f5w6fw6q 3630 4 is be VBZ cord-006870-f5w6fw6q 3630 5 followed follow VBN cord-006870-f5w6fw6q 3630 6 by by IN cord-006870-f5w6fw6q 3630 7 a a DT cord-006870-f5w6fw6q 3630 8 hands hand NNS cord-006870-f5w6fw6q 3630 9 - - HYPH cord-006870-f5w6fw6q 3630 10 on on RP cord-006870-f5w6fw6q 3630 11 simulation simulation NN cord-006870-f5w6fw6q 3630 12 session session NN cord-006870-f5w6fw6q 3630 13 using use VBG cord-006870-f5w6fw6q 3630 14 mannequins mannequin NNS cord-006870-f5w6fw6q 3630 15 . . . cord-006870-f5w6fw6q 3631 1 Standardized standardized JJ cord-006870-f5w6fw6q 3631 2 - - HYPH cord-006870-f5w6fw6q 3631 3 surveys survey NNS cord-006870-f5w6fw6q 3631 4 are be VBP cord-006870-f5w6fw6q 3631 5 administered administer VBN cord-006870-f5w6fw6q 3631 6 to to IN cord-006870-f5w6fw6q 3631 7 nurses nurse NNS cord-006870-f5w6fw6q 3631 8 before before IN cord-006870-f5w6fw6q 3631 9 training training NN cord-006870-f5w6fw6q 3631 10 and and CC cord-006870-f5w6fw6q 3631 11 then then RB cord-006870-f5w6fw6q 3631 12 at at IN cord-006870-f5w6fw6q 3631 13 3 3 CD cord-006870-f5w6fw6q 3631 14 and and CC cord-006870-f5w6fw6q 3631 15 6 6 CD cord-006870-f5w6fw6q 3631 16 months month NNS cord-006870-f5w6fw6q 3631 17 post post NN cord-006870-f5w6fw6q 3631 18 training training NN cord-006870-f5w6fw6q 3631 19 . . . cord-006870-f5w6fw6q 3632 1 We -PRON- PRP cord-006870-f5w6fw6q 3632 2 are be VBP cord-006870-f5w6fw6q 3632 3 prospectively prospectively RB cord-006870-f5w6fw6q 3632 4 collecting collect VBG cord-006870-f5w6fw6q 3632 5 data datum NNS cord-006870-f5w6fw6q 3632 6 on on IN cord-006870-f5w6fw6q 3632 7 nurse nurse NN cord-006870-f5w6fw6q 3632 8 comfort comfort NN cord-006870-f5w6fw6q 3632 9 level level NN cord-006870-f5w6fw6q 3632 10 with with IN cord-006870-f5w6fw6q 3632 11 ultrasound ultrasound NN cord-006870-f5w6fw6q 3632 12 - - HYPH cord-006870-f5w6fw6q 3632 13 guided guide VBN cord-006870-f5w6fw6q 3632 14 PIV PIV NNP cord-006870-f5w6fw6q 3632 15 placement placement NN cord-006870-f5w6fw6q 3632 16 , , , cord-006870-f5w6fw6q 3632 17 total total JJ cord-006870-f5w6fw6q 3632 18 IV IV NNP cord-006870-f5w6fw6q 3632 19 attempts attempt NNS cord-006870-f5w6fw6q 3632 20 , , , cord-006870-f5w6fw6q 3632 21 patient patient JJ cord-006870-f5w6fw6q 3632 22 central central JJ cord-006870-f5w6fw6q 3632 23 line line NN cord-006870-f5w6fw6q 3632 24 associated associate VBN cord-006870-f5w6fw6q 3632 25 bacteremia bacteremia NN cord-006870-f5w6fw6q 3632 26 ( ( -LRB- cord-006870-f5w6fw6q 3632 27 CLAB CLAB NNP cord-006870-f5w6fw6q 3632 28 ) ) -RRB- cord-006870-f5w6fw6q 3632 29 rates rate NNS cord-006870-f5w6fw6q 3632 30 and and CC cord-006870-f5w6fw6q 3632 31 total total JJ cord-006870-f5w6fw6q 3632 32 number number NN cord-006870-f5w6fw6q 3632 33 of of IN cord-006870-f5w6fw6q 3632 34 patient patient JJ cord-006870-f5w6fw6q 3632 35 central central JJ cord-006870-f5w6fw6q 3632 36 line line NN cord-006870-f5w6fw6q 3632 37 days day NNS cord-006870-f5w6fw6q 3632 38 . . . cord-006870-f5w6fw6q 3633 1 We -PRON- PRP cord-006870-f5w6fw6q 3633 2 will will MD cord-006870-f5w6fw6q 3633 3 compare compare VB cord-006870-f5w6fw6q 3633 4 this this DT cord-006870-f5w6fw6q 3633 5 data data NN cord-006870-f5w6fw6q 3633 6 for for IN cord-006870-f5w6fw6q 3633 7 6 6 CD cord-006870-f5w6fw6q 3633 8 months month NNS cord-006870-f5w6fw6q 3633 9 pre pre VBN cord-006870-f5w6fw6q 3633 10 - - JJ cord-006870-f5w6fw6q 3633 11 and and CC cord-006870-f5w6fw6q 3633 12 post post VB cord-006870-f5w6fw6q 3633 13 program program NN cord-006870-f5w6fw6q 3633 14 implementation implementation NN cord-006870-f5w6fw6q 3633 15 . . . cord-006870-f5w6fw6q 3634 1 Comparisons comparison NNS cord-006870-f5w6fw6q 3634 2 will will MD cord-006870-f5w6fw6q 3634 3 be be VB cord-006870-f5w6fw6q 3634 4 made make VBN cord-006870-f5w6fw6q 3634 5 using use VBG cord-006870-f5w6fw6q 3634 6 t t NN cord-006870-f5w6fw6q 3634 7 - - HYPH cord-006870-f5w6fw6q 3634 8 test test NN cord-006870-f5w6fw6q 3634 9 and and CC cord-006870-f5w6fw6q 3634 10 Chi Chi NNP cord-006870-f5w6fw6q 3634 11 - - HYPH cord-006870-f5w6fw6q 3634 12 square square JJ cord-006870-f5w6fw6q 3634 13 analyses analysis NNS cord-006870-f5w6fw6q 3634 14 or or CC cord-006870-f5w6fw6q 3634 15 non non JJ cord-006870-f5w6fw6q 3634 16 - - JJ cord-006870-f5w6fw6q 3634 17 parametric parametric JJ cord-006870-f5w6fw6q 3634 18 equivalents equivalent NNS cord-006870-f5w6fw6q 3634 19 depending depend VBG cord-006870-f5w6fw6q 3634 20 on on IN cord-006870-f5w6fw6q 3634 21 data datum NNS cord-006870-f5w6fw6q 3634 22 distribution distribution NN cord-006870-f5w6fw6q 3634 23 . . . cord-006870-f5w6fw6q 3635 1 Central central JJ cord-006870-f5w6fw6q 3635 2 - - HYPH cord-006870-f5w6fw6q 3635 3 line line NN cord-006870-f5w6fw6q 3635 4 related relate VBN cord-006870-f5w6fw6q 3635 5 complications complication NNS cord-006870-f5w6fw6q 3635 6 are be VBP cord-006870-f5w6fw6q 3635 7 an an DT cord-006870-f5w6fw6q 3635 8 important important JJ cord-006870-f5w6fw6q 3635 9 clinical clinical JJ cord-006870-f5w6fw6q 3635 10 problem problem NN cord-006870-f5w6fw6q 3635 11 in in IN cord-006870-f5w6fw6q 3635 12 all all DT cord-006870-f5w6fw6q 3635 13 ICUs icus XX cord-006870-f5w6fw6q 3635 14 . . . cord-006870-f5w6fw6q 3636 1 We -PRON- PRP cord-006870-f5w6fw6q 3636 2 have have VBP cord-006870-f5w6fw6q 3636 3 developed develop VBN cord-006870-f5w6fw6q 3636 4 and and CC cord-006870-f5w6fw6q 3636 5 implemented implement VBN cord-006870-f5w6fw6q 3636 6 a a DT cord-006870-f5w6fw6q 3636 7 systematic systematic JJ cord-006870-f5w6fw6q 3636 8 training training NN cord-006870-f5w6fw6q 3636 9 program program NN cord-006870-f5w6fw6q 3636 10 to to TO cord-006870-f5w6fw6q 3636 11 support support VB cord-006870-f5w6fw6q 3636 12 nursing nursing NN cord-006870-f5w6fw6q 3636 13 - - HYPH cord-006870-f5w6fw6q 3636 14 led lead VBN cord-006870-f5w6fw6q 3636 15 ultrasound ultrasound NN cord-006870-f5w6fw6q 3636 16 - - HYPH cord-006870-f5w6fw6q 3636 17 guided guide VBN cord-006870-f5w6fw6q 3636 18 PIV PIV NNP cord-006870-f5w6fw6q 3636 19 placement placement NN cord-006870-f5w6fw6q 3636 20 . . . cord-006870-f5w6fw6q 3637 1 We -PRON- PRP cord-006870-f5w6fw6q 3637 2 will will MD cord-006870-f5w6fw6q 3637 3 determine determine VB cord-006870-f5w6fw6q 3637 4 if if IN cord-006870-f5w6fw6q 3637 5 this this DT cord-006870-f5w6fw6q 3637 6 program program NN cord-006870-f5w6fw6q 3637 7 reduces reduce VBZ cord-006870-f5w6fw6q 3637 8 the the DT cord-006870-f5w6fw6q 3637 9 overall overall JJ cord-006870-f5w6fw6q 3637 10 number number NN cord-006870-f5w6fw6q 3637 11 of of IN cord-006870-f5w6fw6q 3637 12 central central JJ cord-006870-f5w6fw6q 3637 13 lines line NNS cord-006870-f5w6fw6q 3637 14 placed place VBN cord-006870-f5w6fw6q 3637 15 , , , cord-006870-f5w6fw6q 3637 16 duration duration NN cord-006870-f5w6fw6q 3637 17 of of IN cord-006870-f5w6fw6q 3637 18 indwelling indwell VBG cord-006870-f5w6fw6q 3637 19 central central JJ cord-006870-f5w6fw6q 3637 20 lines line NNS cord-006870-f5w6fw6q 3637 21 , , , cord-006870-f5w6fw6q 3637 22 and and CC cord-006870-f5w6fw6q 3637 23 CLAB CLAB NNP cord-006870-f5w6fw6q 3637 24 rates rate NNS cord-006870-f5w6fw6q 3637 25 in in IN cord-006870-f5w6fw6q 3637 26 a a DT cord-006870-f5w6fw6q 3637 27 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3637 28 care care NN cord-006870-f5w6fw6q 3637 29 , , , cord-006870-f5w6fw6q 3637 30 and and CC cord-006870-f5w6fw6q 3637 31 subsequently subsequently RB cord-006870-f5w6fw6q 3637 32 expand expand VB cord-006870-f5w6fw6q 3637 33 to to IN cord-006870-f5w6fw6q 3637 34 additional additional JJ cord-006870-f5w6fw6q 3637 35 ICUs icu NNS cord-006870-f5w6fw6q 3637 36 and and CC cord-006870-f5w6fw6q 3637 37 beyond beyond IN cord-006870-f5w6fw6q 3637 38 . . . cord-006870-f5w6fw6q 3638 1 Ultrasound ultrasound NN cord-006870-f5w6fw6q 3638 2 measurement measurement NN cord-006870-f5w6fw6q 3638 3 of of IN cord-006870-f5w6fw6q 3638 4 optic optic JJ cord-006870-f5w6fw6q 3638 5 nerve nerve NN cord-006870-f5w6fw6q 3638 6 sheath sheath NN cord-006870-f5w6fw6q 3638 7 diameter diameter NN cord-006870-f5w6fw6q 3638 8 ( ( -LRB- cord-006870-f5w6fw6q 3638 9 ONSD ONSD NNP cord-006870-f5w6fw6q 3638 10 ) ) -RRB- cord-006870-f5w6fw6q 3638 11 is be VBZ cord-006870-f5w6fw6q 3638 12 a a DT cord-006870-f5w6fw6q 3638 13 sensitive sensitive JJ cord-006870-f5w6fw6q 3638 14 and and CC cord-006870-f5w6fw6q 3638 15 specific specific JJ cord-006870-f5w6fw6q 3638 16 non non JJ cord-006870-f5w6fw6q 3638 17 - - JJ cord-006870-f5w6fw6q 3638 18 invasive invasive JJ cord-006870-f5w6fw6q 3638 19 ultrasonographers ultrasonographer NNS cord-006870-f5w6fw6q 3638 20 . . . cord-006870-f5w6fw6q 3639 1 Despite despite IN cord-006870-f5w6fw6q 3639 2 clinical clinical JJ cord-006870-f5w6fw6q 3639 3 applications application NNS cord-006870-f5w6fw6q 3639 4 in in IN cord-006870-f5w6fw6q 3639 5 the the DT cord-006870-f5w6fw6q 3639 6 ICU ICU NNP cord-006870-f5w6fw6q 3639 7 , , , cord-006870-f5w6fw6q 3639 8 ER ER NNP cord-006870-f5w6fw6q 3639 9 and and CC cord-006870-f5w6fw6q 3639 10 outpatient outpatient NN cord-006870-f5w6fw6q 3639 11 settings setting NNS cord-006870-f5w6fw6q 3639 12 , , , cord-006870-f5w6fw6q 3639 13 neurology neurology NN cord-006870-f5w6fw6q 3639 14 residents resident NNS cord-006870-f5w6fw6q 3639 15 lack lack VBP cord-006870-f5w6fw6q 3639 16 experience experience NN cord-006870-f5w6fw6q 3639 17 and and CC cord-006870-f5w6fw6q 3639 18 training training NN cord-006870-f5w6fw6q 3639 19 . . . cord-006870-f5w6fw6q 3640 1 The the DT cord-006870-f5w6fw6q 3640 2 aim aim NN cord-006870-f5w6fw6q 3640 3 of of IN cord-006870-f5w6fw6q 3640 4 our -PRON- PRP$ cord-006870-f5w6fw6q 3640 5 project project NN cord-006870-f5w6fw6q 3640 6 was be VBD cord-006870-f5w6fw6q 3640 7 to to TO cord-006870-f5w6fw6q 3640 8 provide provide VB cord-006870-f5w6fw6q 3640 9 neurology neurology NN cord-006870-f5w6fw6q 3640 10 residents resident NNS cord-006870-f5w6fw6q 3640 11 with with IN cord-006870-f5w6fw6q 3640 12 foundational foundational JJ cord-006870-f5w6fw6q 3640 13 skills skill NNS cord-006870-f5w6fw6q 3640 14 in in IN cord-006870-f5w6fw6q 3640 15 ocular ocular JJ cord-006870-f5w6fw6q 3640 16 ultrasound ultrasound NN cord-006870-f5w6fw6q 3640 17 and and CC cord-006870-f5w6fw6q 3640 18 ONSD ONSD NNP cord-006870-f5w6fw6q 3640 19 measurement measurement NN cord-006870-f5w6fw6q 3640 20 . . . cord-006870-f5w6fw6q 3641 1 We -PRON- PRP cord-006870-f5w6fw6q 3641 2 designed design VBD cord-006870-f5w6fw6q 3641 3 a a DT cord-006870-f5w6fw6q 3641 4 two two CD cord-006870-f5w6fw6q 3641 5 - - HYPH cord-006870-f5w6fw6q 3641 6 part part NN cord-006870-f5w6fw6q 3641 7 workshop workshop NN cord-006870-f5w6fw6q 3641 8 for for IN cord-006870-f5w6fw6q 3641 9 neurology neurology NN cord-006870-f5w6fw6q 3641 10 residents resident NNS cord-006870-f5w6fw6q 3641 11 covering cover VBG cord-006870-f5w6fw6q 3641 12 ultrasound ultrasound NN cord-006870-f5w6fw6q 3641 13 basics basic NNS cord-006870-f5w6fw6q 3641 14 , , , cord-006870-f5w6fw6q 3641 15 measurement measurement NN cord-006870-f5w6fw6q 3641 16 of of IN cord-006870-f5w6fw6q 3641 17 ONSD ONSD NNP cord-006870-f5w6fw6q 3641 18 , , , cord-006870-f5w6fw6q 3641 19 and and CC cord-006870-f5w6fw6q 3641 20 ultrasound ultrasound NN cord-006870-f5w6fw6q 3641 21 appearance appearance NN cord-006870-f5w6fw6q 3641 22 of of IN cord-006870-f5w6fw6q 3641 23 papilledema papilledema NNP cord-006870-f5w6fw6q 3641 24 . . . cord-006870-f5w6fw6q 3642 1 Workshop workshop NN cord-006870-f5w6fw6q 3642 2 1 1 CD cord-006870-f5w6fw6q 3642 3 was be VBD cord-006870-f5w6fw6q 3642 4 a a DT cord-006870-f5w6fw6q 3642 5 30 30 CD cord-006870-f5w6fw6q 3642 6 minute minute NN cord-006870-f5w6fw6q 3642 7 lecture lecture NN cord-006870-f5w6fw6q 3642 8 and and CC cord-006870-f5w6fw6q 3642 9 demonstration demonstration NN cord-006870-f5w6fw6q 3642 10 followed follow VBN cord-006870-f5w6fw6q 3642 11 by by IN cord-006870-f5w6fw6q 3642 12 90 90 CD cord-006870-f5w6fw6q 3642 13 minutes minute NNS cord-006870-f5w6fw6q 3642 14 of of IN cord-006870-f5w6fw6q 3642 15 hands hand NNS cord-006870-f5w6fw6q 3642 16 - - HYPH cord-006870-f5w6fw6q 3642 17 on on RP cord-006870-f5w6fw6q 3642 18 practice practice NN cord-006870-f5w6fw6q 3642 19 . . . cord-006870-f5w6fw6q 3643 1 Two two CD cord-006870-f5w6fw6q 3643 2 weeks week NNS cord-006870-f5w6fw6q 3643 3 later later RB cord-006870-f5w6fw6q 3643 4 , , , cord-006870-f5w6fw6q 3643 5 workshop workshop NN cord-006870-f5w6fw6q 3643 6 2 2 CD cord-006870-f5w6fw6q 3643 7 included include VBD cord-006870-f5w6fw6q 3643 8 60 60 CD cord-006870-f5w6fw6q 3643 9 additional additional JJ cord-006870-f5w6fw6q 3643 10 minutes minute NNS cord-006870-f5w6fw6q 3643 11 of of IN cord-006870-f5w6fw6q 3643 12 practice practice NN cord-006870-f5w6fw6q 3643 13 to to TO cord-006870-f5w6fw6q 3643 14 consolidate consolidate VB cord-006870-f5w6fw6q 3643 15 learning learning NN cord-006870-f5w6fw6q 3643 16 . . . cord-006870-f5w6fw6q 3644 1 The the DT cord-006870-f5w6fw6q 3644 2 practical practical JJ cord-006870-f5w6fw6q 3644 3 portions portion NNS cord-006870-f5w6fw6q 3644 4 were be VBD cord-006870-f5w6fw6q 3644 5 facilitated facilitate VBN cord-006870-f5w6fw6q 3644 6 by by IN cord-006870-f5w6fw6q 3644 7 emergency emergency NN cord-006870-f5w6fw6q 3644 8 medicine medicine NN cord-006870-f5w6fw6q 3644 9 attendings attending NNS cord-006870-f5w6fw6q 3644 10 and and CC cord-006870-f5w6fw6q 3644 11 residents resident NNS cord-006870-f5w6fw6q 3644 12 with with IN cord-006870-f5w6fw6q 3644 13 experience experience NN cord-006870-f5w6fw6q 3644 14 in in IN cord-006870-f5w6fw6q 3644 15 performing perform VBG cord-006870-f5w6fw6q 3644 16 ocular ocular JJ cord-006870-f5w6fw6q 3644 17 ultrasounds ultrasound NNS cord-006870-f5w6fw6q 3644 18 . . . cord-006870-f5w6fw6q 3645 1 Neurology Neurology NNP cord-006870-f5w6fw6q 3645 2 residents resident NNS cord-006870-f5w6fw6q 3645 3 tracked track VBD cord-006870-f5w6fw6q 3645 4 the the DT cord-006870-f5w6fw6q 3645 5 number number NN cord-006870-f5w6fw6q 3645 6 of of IN cord-006870-f5w6fw6q 3645 7 practice practice NN cord-006870-f5w6fw6q 3645 8 ultrasounds ultrasound NNS cord-006870-f5w6fw6q 3645 9 performed perform VBN cord-006870-f5w6fw6q 3645 10 . . . cord-006870-f5w6fw6q 3646 1 They -PRON- PRP cord-006870-f5w6fw6q 3646 2 also also RB cord-006870-f5w6fw6q 3646 3 completed complete VBD cord-006870-f5w6fw6q 3646 4 anonymous anonymous JJ cord-006870-f5w6fw6q 3646 5 pre pre JJ cord-006870-f5w6fw6q 3646 6 - - JJ cord-006870-f5w6fw6q 3646 7 and and CC cord-006870-f5w6fw6q 3646 8 posttests posttest NNS cord-006870-f5w6fw6q 3646 9 to to TO cord-006870-f5w6fw6q 3646 10 assess assess VB cord-006870-f5w6fw6q 3646 11 their -PRON- PRP$ cord-006870-f5w6fw6q 3646 12 knowledge knowledge NN cord-006870-f5w6fw6q 3646 13 of of IN cord-006870-f5w6fw6q 3646 14 ocular ocular JJ cord-006870-f5w6fw6q 3646 15 ultrasound ultrasound NN cord-006870-f5w6fw6q 3646 16 and and CC cord-006870-f5w6fw6q 3646 17 their -PRON- PRP$ cord-006870-f5w6fw6q 3646 18 comfort comfort NN cord-006870-f5w6fw6q 3646 19 level level NN cord-006870-f5w6fw6q 3646 20 and and CC cord-006870-f5w6fw6q 3646 21 likelihood likelihood NN cord-006870-f5w6fw6q 3646 22 to to TO cord-006870-f5w6fw6q 3646 23 perform perform VB cord-006870-f5w6fw6q 3646 24 future future JJ cord-006870-f5w6fw6q 3646 25 procedures procedure NNS cord-006870-f5w6fw6q 3646 26 using use VBG cord-006870-f5w6fw6q 3646 27 a a DT cord-006870-f5w6fw6q 3646 28 6-point 6-point VBN cord-006870-f5w6fw6q 3646 29 Likert Likert NNP cord-006870-f5w6fw6q 3646 30 scale scale NN cord-006870-f5w6fw6q 3646 31 . . . cord-006870-f5w6fw6q 3647 1 Prior prior RB cord-006870-f5w6fw6q 3647 2 to to IN cord-006870-f5w6fw6q 3647 3 the the DT cord-006870-f5w6fw6q 3647 4 workshop workshop NN cord-006870-f5w6fw6q 3647 5 , , , cord-006870-f5w6fw6q 3647 6 the the DT cord-006870-f5w6fw6q 3647 7 majority majority NN cord-006870-f5w6fw6q 3647 8 ( ( -LRB- cord-006870-f5w6fw6q 3647 9 14/19 14/19 CD cord-006870-f5w6fw6q 3647 10 ) ) -RRB- cord-006870-f5w6fw6q 3647 11 of of IN cord-006870-f5w6fw6q 3647 12 neurology neurology NN cord-006870-f5w6fw6q 3647 13 trainees trainee NNS cord-006870-f5w6fw6q 3647 14 had have VBD cord-006870-f5w6fw6q 3647 15 never never RB cord-006870-f5w6fw6q 3647 16 performed perform VBN cord-006870-f5w6fw6q 3647 17 an an DT cord-006870-f5w6fw6q 3647 18 ocular ocular JJ cord-006870-f5w6fw6q 3647 19 ultrasound ultrasound NN cord-006870-f5w6fw6q 3647 20 . . . cord-006870-f5w6fw6q 3648 1 One one CD cord-006870-f5w6fw6q 3648 2 ( ( -LRB- cord-006870-f5w6fw6q 3648 3 1/19 1/19 CD cord-006870-f5w6fw6q 3648 4 ) ) -RRB- cord-006870-f5w6fw6q 3648 5 was be VBD cord-006870-f5w6fw6q 3648 6 able able JJ cord-006870-f5w6fw6q 3648 7 to to TO cord-006870-f5w6fw6q 3648 8 answer answer VB cord-006870-f5w6fw6q 3648 9 two two CD cord-006870-f5w6fw6q 3648 10 basic basic JJ cord-006870-f5w6fw6q 3648 11 questions question NNS cord-006870-f5w6fw6q 3648 12 about about IN cord-006870-f5w6fw6q 3648 13 the the DT cord-006870-f5w6fw6q 3648 14 procedure procedure NN cord-006870-f5w6fw6q 3648 15 correctly correctly RB cord-006870-f5w6fw6q 3648 16 , , , cord-006870-f5w6fw6q 3648 17 which which WDT cord-006870-f5w6fw6q 3648 18 increased increase VBD cord-006870-f5w6fw6q 3648 19 to to IN cord-006870-f5w6fw6q 3648 20 100 100 CD cord-006870-f5w6fw6q 3648 21 % % NN cord-006870-f5w6fw6q 3648 22 on on IN cord-006870-f5w6fw6q 3648 23 the the DT cord-006870-f5w6fw6q 3648 24 posttest posttest NNP cord-006870-f5w6fw6q 3648 25 ( ( -LRB- cord-006870-f5w6fw6q 3648 26 n=16 n=16 NNP cord-006870-f5w6fw6q 3648 27 ) ) -RRB- cord-006870-f5w6fw6q 3648 28 . . . cord-006870-f5w6fw6q 3649 1 Trainees trainee NNS cord-006870-f5w6fw6q 3649 2 performed perform VBD cord-006870-f5w6fw6q 3649 3 an an DT cord-006870-f5w6fw6q 3649 4 average average NN cord-006870-f5w6fw6q 3649 5 of of IN cord-006870-f5w6fw6q 3649 6 5 5 CD cord-006870-f5w6fw6q 3649 7 ultrasounds ultrasound NNS cord-006870-f5w6fw6q 3649 8 total total VBP cord-006870-f5w6fw6q 3649 9 during during IN cord-006870-f5w6fw6q 3649 10 the the DT cord-006870-f5w6fw6q 3649 11 workshops workshop NNS cord-006870-f5w6fw6q 3649 12 . . . cord-006870-f5w6fw6q 3650 1 Resident resident JJ cord-006870-f5w6fw6q 3650 2 self self NN cord-006870-f5w6fw6q 3650 3 - - HYPH cord-006870-f5w6fw6q 3650 4 assessment assessment NN cord-006870-f5w6fw6q 3650 5 of of IN cord-006870-f5w6fw6q 3650 6 comfort comfort NN cord-006870-f5w6fw6q 3650 7 performing perform VBG cord-006870-f5w6fw6q 3650 8 the the DT cord-006870-f5w6fw6q 3650 9 procedure procedure NN cord-006870-f5w6fw6q 3650 10 increased increase VBD cord-006870-f5w6fw6q 3650 11 from from IN cord-006870-f5w6fw6q 3650 12 a a DT cord-006870-f5w6fw6q 3650 13 median median NN cord-006870-f5w6fw6q 3650 14 of of IN cord-006870-f5w6fw6q 3650 15 " " `` cord-006870-f5w6fw6q 3650 16 very very RB cord-006870-f5w6fw6q 3650 17 uncomfortable uncomfortable JJ cord-006870-f5w6fw6q 3650 18 " " '' cord-006870-f5w6fw6q 3650 19 to to TO cord-006870-f5w6fw6q 3650 20 " " `` cord-006870-f5w6fw6q 3650 21 moderately moderately RB cord-006870-f5w6fw6q 3650 22 comfortable comfortable JJ cord-006870-f5w6fw6q 3650 23 " " '' cord-006870-f5w6fw6q 3650 24 on on IN cord-006870-f5w6fw6q 3650 25 the the DT cord-006870-f5w6fw6q 3650 26 6-point 6-point NNP cord-006870-f5w6fw6q 3650 27 Likert Likert NNP cord-006870-f5w6fw6q 3650 28 scale scale NN cord-006870-f5w6fw6q 3650 29 ( ( -LRB- cord-006870-f5w6fw6q 3650 30 p=0.001 p=0.001 NNS cord-006870-f5w6fw6q 3650 31 ) ) -RRB- cord-006870-f5w6fw6q 3650 32 . . . cord-006870-f5w6fw6q 3651 1 Resident resident JJ cord-006870-f5w6fw6q 3651 2 likelihood likelihood NN cord-006870-f5w6fw6q 3651 3 to to TO cord-006870-f5w6fw6q 3651 4 perform perform VB cord-006870-f5w6fw6q 3651 5 the the DT cord-006870-f5w6fw6q 3651 6 procedure procedure NN cord-006870-f5w6fw6q 3651 7 in in IN cord-006870-f5w6fw6q 3651 8 the the DT cord-006870-f5w6fw6q 3651 9 future future NN cord-006870-f5w6fw6q 3651 10 increased increase VBD cord-006870-f5w6fw6q 3651 11 from from IN cord-006870-f5w6fw6q 3651 12 a a DT cord-006870-f5w6fw6q 3651 13 median median NN cord-006870-f5w6fw6q 3651 14 of of IN cord-006870-f5w6fw6q 3651 15 " " `` cord-006870-f5w6fw6q 3651 16 very very RB cord-006870-f5w6fw6q 3651 17 unlikely unlikely JJ cord-006870-f5w6fw6q 3651 18 " " '' cord-006870-f5w6fw6q 3651 19 to to TO cord-006870-f5w6fw6q 3651 20 " " `` cord-006870-f5w6fw6q 3651 21 moderately moderately RB cord-006870-f5w6fw6q 3651 22 likely likely JJ cord-006870-f5w6fw6q 3651 23 " " '' cord-006870-f5w6fw6q 3651 24 on on IN cord-006870-f5w6fw6q 3651 25 the the DT cord-006870-f5w6fw6q 3651 26 6-point 6-point NNP cord-006870-f5w6fw6q 3651 27 Likert Likert NNP cord-006870-f5w6fw6q 3651 28 scale scale NN cord-006870-f5w6fw6q 3651 29 ( ( -LRB- cord-006870-f5w6fw6q 3651 30 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 3651 31 ) ) -RRB- cord-006870-f5w6fw6q 3651 32 . . . cord-006870-f5w6fw6q 3652 1 This this DT cord-006870-f5w6fw6q 3652 2 session session NN cord-006870-f5w6fw6q 3652 3 successfully successfully RB cord-006870-f5w6fw6q 3652 4 increased increase VBD cord-006870-f5w6fw6q 3652 5 basic basic JJ cord-006870-f5w6fw6q 3652 6 knowledge knowledge NN cord-006870-f5w6fw6q 3652 7 , , , cord-006870-f5w6fw6q 3652 8 comfort comfort NN cord-006870-f5w6fw6q 3652 9 , , , cord-006870-f5w6fw6q 3652 10 and and CC cord-006870-f5w6fw6q 3652 11 likelihood likelihood NN cord-006870-f5w6fw6q 3652 12 to to TO cord-006870-f5w6fw6q 3652 13 perform perform VB cord-006870-f5w6fw6q 3652 14 ocular ocular JJ cord-006870-f5w6fw6q 3652 15 ultrasound ultrasound NN cord-006870-f5w6fw6q 3652 16 among among IN cord-006870-f5w6fw6q 3652 17 neurology neurology NN cord-006870-f5w6fw6q 3652 18 residents resident NNS cord-006870-f5w6fw6q 3652 19 . . . cord-006870-f5w6fw6q 3653 1 Future future JJ cord-006870-f5w6fw6q 3653 2 directions direction NNS cord-006870-f5w6fw6q 3653 3 include include VBP cord-006870-f5w6fw6q 3653 4 follow follow NN cord-006870-f5w6fw6q 3653 5 - - HYPH cord-006870-f5w6fw6q 3653 6 up up NN cord-006870-f5w6fw6q 3653 7 to to TO cord-006870-f5w6fw6q 3653 8 gauge gauge VB cord-006870-f5w6fw6q 3653 9 magnitude magnitude NN cord-006870-f5w6fw6q 3653 10 of of IN cord-006870-f5w6fw6q 3653 11 practice practice NN cord-006870-f5w6fw6q 3653 12 changes change NNS cord-006870-f5w6fw6q 3653 13 and and CC cord-006870-f5w6fw6q 3653 14 accuracy accuracy NN cord-006870-f5w6fw6q 3653 15 of of IN cord-006870-f5w6fw6q 3653 16 procedural procedural JJ cord-006870-f5w6fw6q 3653 17 skills skill NNS cord-006870-f5w6fw6q 3653 18 . . . cord-006870-f5w6fw6q 3654 1 Reaching reach VBG cord-006870-f5w6fw6q 3654 2 patients patient NNS cord-006870-f5w6fw6q 3654 3 by by IN cord-006870-f5w6fw6q 3654 4 telephone telephone NN cord-006870-f5w6fw6q 3654 5 is be VBZ cord-006870-f5w6fw6q 3654 6 a a DT cord-006870-f5w6fw6q 3654 7 common common JJ cord-006870-f5w6fw6q 3654 8 method method NN cord-006870-f5w6fw6q 3654 9 of of IN cord-006870-f5w6fw6q 3654 10 assessing assess VBG cord-006870-f5w6fw6q 3654 11 functional functional JJ cord-006870-f5w6fw6q 3654 12 outcome outcome NN cord-006870-f5w6fw6q 3654 13 , , , cord-006870-f5w6fw6q 3654 14 cognitive cognitive JJ cord-006870-f5w6fw6q 3654 15 function function NN cord-006870-f5w6fw6q 3654 16 , , , cord-006870-f5w6fw6q 3654 17 and and CC cord-006870-f5w6fw6q 3654 18 quality quality NN cord-006870-f5w6fw6q 3654 19 of of IN cord-006870-f5w6fw6q 3654 20 life life NN cord-006870-f5w6fw6q 3654 21 after after IN cord-006870-f5w6fw6q 3654 22 hospital hospital NN cord-006870-f5w6fw6q 3654 23 discharge discharge NN cord-006870-f5w6fw6q 3654 24 . . . cord-006870-f5w6fw6q 3655 1 However however RB cord-006870-f5w6fw6q 3655 2 , , , cord-006870-f5w6fw6q 3655 3 when when WRB cord-006870-f5w6fw6q 3655 4 patients patient NNS cord-006870-f5w6fw6q 3655 5 do do VBP cord-006870-f5w6fw6q 3655 6 not not RB cord-006870-f5w6fw6q 3655 7 answer answer VB cord-006870-f5w6fw6q 3655 8 the the DT cord-006870-f5w6fw6q 3655 9 phone phone NN cord-006870-f5w6fw6q 3655 10 , , , cord-006870-f5w6fw6q 3655 11 missing miss VBG cord-006870-f5w6fw6q 3655 12 data data NN cord-006870-f5w6fw6q 3655 13 creates create VBZ cord-006870-f5w6fw6q 3655 14 bias bias NN cord-006870-f5w6fw6q 3655 15 and and CC cord-006870-f5w6fw6q 3655 16 warrants warrant VBZ cord-006870-f5w6fw6q 3655 17 strategies strategy NNS cord-006870-f5w6fw6q 3655 18 to to TO cord-006870-f5w6fw6q 3655 19 increase increase VB cord-006870-f5w6fw6q 3655 20 follow follow VB cord-006870-f5w6fw6q 3655 21 - - HYPH cord-006870-f5w6fw6q 3655 22 up up RP cord-006870-f5w6fw6q 3655 23 rates rate NNS cord-006870-f5w6fw6q 3655 24 . . . cord-006870-f5w6fw6q 3656 1 We -PRON- PRP cord-006870-f5w6fw6q 3656 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 3656 3 that that IN cord-006870-f5w6fw6q 3656 4 we -PRON- PRP cord-006870-f5w6fw6q 3656 5 would would MD cord-006870-f5w6fw6q 3656 6 have have VB cord-006870-f5w6fw6q 3656 7 less less JJR cord-006870-f5w6fw6q 3656 8 follow follow VB cord-006870-f5w6fw6q 3656 9 up up RP cord-006870-f5w6fw6q 3656 10 with with IN cord-006870-f5w6fw6q 3656 11 patients patient NNS cord-006870-f5w6fw6q 3656 12 discharged discharge VBN cord-006870-f5w6fw6q 3656 13 to to IN cord-006870-f5w6fw6q 3656 14 long long JJ cord-006870-f5w6fw6q 3656 15 - - HYPH cord-006870-f5w6fw6q 3656 16 term term NN cord-006870-f5w6fw6q 3656 17 care care NN cord-006870-f5w6fw6q 3656 18 facilities facility NNS cord-006870-f5w6fw6q 3656 19 and and CC cord-006870-f5w6fw6q 3656 20 sought seek VBD cord-006870-f5w6fw6q 3656 21 to to TO cord-006870-f5w6fw6q 3656 22 examine examine VB cord-006870-f5w6fw6q 3656 23 other other JJ cord-006870-f5w6fw6q 3656 24 potential potential JJ cord-006870-f5w6fw6q 3656 25 sources source NNS cord-006870-f5w6fw6q 3656 26 of of IN cord-006870-f5w6fw6q 3656 27 lost lose VBN cord-006870-f5w6fw6q 3656 28 data datum NNS cord-006870-f5w6fw6q 3656 29 . . . cord-006870-f5w6fw6q 3657 1 Between between IN cord-006870-f5w6fw6q 3657 2 1/2016 1/2016 CD cord-006870-f5w6fw6q 3657 3 and and CC cord-006870-f5w6fw6q 3657 4 3/2017 3/2017 CD cord-006870-f5w6fw6q 3657 5 , , , cord-006870-f5w6fw6q 3657 6 we -PRON- PRP cord-006870-f5w6fw6q 3657 7 identified identify VBD cord-006870-f5w6fw6q 3657 8 all all DT cord-006870-f5w6fw6q 3657 9 patients patient NNS cord-006870-f5w6fw6q 3657 10 admitted admit VBN cord-006870-f5w6fw6q 3657 11 to to IN cord-006870-f5w6fw6q 3657 12 the the DT cord-006870-f5w6fw6q 3657 13 University University NNP cord-006870-f5w6fw6q 3657 14 of of IN cord-006870-f5w6fw6q 3657 15 Cincinnati Cincinnati NNP cord-006870-f5w6fw6q 3657 16 Neuroscience Neuroscience NNP cord-006870-f5w6fw6q 3657 17 Intensive Intensive NNP cord-006870-f5w6fw6q 3657 18 Care Care NNP cord-006870-f5w6fw6q 3657 19 Unit Unit NNP cord-006870-f5w6fw6q 3657 20 ( ( -LRB- cord-006870-f5w6fw6q 3657 21 NSICU NSICU NNP cord-006870-f5w6fw6q 3657 22 ) ) -RRB- cord-006870-f5w6fw6q 3657 23 . . . cord-006870-f5w6fw6q 3658 1 We -PRON- PRP cord-006870-f5w6fw6q 3658 2 excluded exclude VBD cord-006870-f5w6fw6q 3658 3 those those DT cord-006870-f5w6fw6q 3658 4 with with IN cord-006870-f5w6fw6q 3658 5 recurrent recurrent JJ cord-006870-f5w6fw6q 3658 6 admissions admission NNS cord-006870-f5w6fw6q 3658 7 , , , cord-006870-f5w6fw6q 3658 8 boarders boarder NNS cord-006870-f5w6fw6q 3658 9 , , , cord-006870-f5w6fw6q 3658 10 and and CC cord-006870-f5w6fw6q 3658 11 those those DT cord-006870-f5w6fw6q 3658 12 admitted admit VBD cord-006870-f5w6fw6q 3658 13 < < XX cord-006870-f5w6fw6q 3658 14 24 24 CD cord-006870-f5w6fw6q 3658 15 hours hour NNS cord-006870-f5w6fw6q 3658 16 or or CC cord-006870-f5w6fw6q 3658 17 for for IN cord-006870-f5w6fw6q 3658 18 uncomplicated uncomplicated JJ cord-006870-f5w6fw6q 3658 19 post post JJ cord-006870-f5w6fw6q 3658 20 - - JJ cord-006870-f5w6fw6q 3658 21 op op JJ cord-006870-f5w6fw6q 3658 22 care care NN cord-006870-f5w6fw6q 3658 23 . . . cord-006870-f5w6fw6q 3659 1 Telephone telephone NN cord-006870-f5w6fw6q 3659 2 follow follow NN cord-006870-f5w6fw6q 3659 3 - - HYPH cord-006870-f5w6fw6q 3659 4 up up NN cord-006870-f5w6fw6q 3659 5 was be VBD cord-006870-f5w6fw6q 3659 6 attempted attempt VBN cord-006870-f5w6fw6q 3659 7 for for IN cord-006870-f5w6fw6q 3659 8 each each DT cord-006870-f5w6fw6q 3659 9 patient patient NN cord-006870-f5w6fw6q 3659 10 . . . cord-006870-f5w6fw6q 3660 1 Univariate Univariate NNP cord-006870-f5w6fw6q 3660 2 analysis analysis NN cord-006870-f5w6fw6q 3660 3 was be VBD cord-006870-f5w6fw6q 3660 4 used use VBN cord-006870-f5w6fw6q 3660 5 to to TO cord-006870-f5w6fw6q 3660 6 identify identify VB cord-006870-f5w6fw6q 3660 7 associations association NNS cord-006870-f5w6fw6q 3660 8 with with IN cord-006870-f5w6fw6q 3660 9 patients patient NNS cord-006870-f5w6fw6q 3660 10 who who WP cord-006870-f5w6fw6q 3660 11 did do VBD cord-006870-f5w6fw6q 3660 12 not not RB cord-006870-f5w6fw6q 3660 13 answer answer VB cord-006870-f5w6fw6q 3660 14 the the DT cord-006870-f5w6fw6q 3660 15 phone phone NN cord-006870-f5w6fw6q 3660 16 . . . cord-006870-f5w6fw6q 3661 1 1103 1103 CD cord-006870-f5w6fw6q 3661 2 critically critically RB cord-006870-f5w6fw6q 3661 3 - - HYPH cord-006870-f5w6fw6q 3661 4 ill ill JJ cord-006870-f5w6fw6q 3661 5 patients patient NNS cord-006870-f5w6fw6q 3661 6 were be VBD cord-006870-f5w6fw6q 3661 7 included include VBN cord-006870-f5w6fw6q 3661 8 . . . cord-006870-f5w6fw6q 3662 1 Average average JJ cord-006870-f5w6fw6q 3662 2 age age NN cord-006870-f5w6fw6q 3662 3 was be VBD cord-006870-f5w6fw6q 3662 4 59.7+/-17.6 59.7+/-17.6 CD cord-006870-f5w6fw6q 3662 5 and and CC cord-006870-f5w6fw6q 3662 6 53 53 CD cord-006870-f5w6fw6q 3662 7 % % NN cord-006870-f5w6fw6q 3662 8 were be VBD cord-006870-f5w6fw6q 3662 9 men man NNS cord-006870-f5w6fw6q 3662 10 . . . cord-006870-f5w6fw6q 3663 1 The the DT cord-006870-f5w6fw6q 3663 2 average average JJ cord-006870-f5w6fw6q 3663 3 hospital hospital NN cord-006870-f5w6fw6q 3663 4 length length NN cord-006870-f5w6fw6q 3663 5 - - HYPH cord-006870-f5w6fw6q 3663 6 of of IN cord-006870-f5w6fw6q 3663 7 - - HYPH cord-006870-f5w6fw6q 3663 8 stay stay NN cord-006870-f5w6fw6q 3663 9 was be VBD cord-006870-f5w6fw6q 3663 10 9.4+/-8.9 9.4+/-8.9 CD cord-006870-f5w6fw6q 3663 11 days day NNS cord-006870-f5w6fw6q 3663 12 . . . cord-006870-f5w6fw6q 3664 1 Major major JJ cord-006870-f5w6fw6q 3664 2 diagnoses diagnosis NNS cord-006870-f5w6fw6q 3664 3 were be VBD cord-006870-f5w6fw6q 3664 4 : : : cord-006870-f5w6fw6q 3664 5 ischemic ischemic JJ cord-006870-f5w6fw6q 3664 6 stroke stroke NN cord-006870-f5w6fw6q 3664 7 ( ( -LRB- cord-006870-f5w6fw6q 3664 8 25 25 CD cord-006870-f5w6fw6q 3664 9 % % NN cord-006870-f5w6fw6q 3664 10 ) ) -RRB- cord-006870-f5w6fw6q 3664 11 , , , cord-006870-f5w6fw6q 3664 12 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3664 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3664 14 ( ( -LRB- cord-006870-f5w6fw6q 3664 15 19 19 CD cord-006870-f5w6fw6q 3664 16 % % NN cord-006870-f5w6fw6q 3664 17 ) ) -RRB- cord-006870-f5w6fw6q 3664 18 , , , cord-006870-f5w6fw6q 3664 19 traumatic traumatic JJ cord-006870-f5w6fw6q 3664 20 brain brain NN cord-006870-f5w6fw6q 3664 21 injury injury NN cord-006870-f5w6fw6q 3664 22 ( ( -LRB- cord-006870-f5w6fw6q 3664 23 15 15 CD cord-006870-f5w6fw6q 3664 24 % % NN cord-006870-f5w6fw6q 3664 25 ) ) -RRB- cord-006870-f5w6fw6q 3664 26 , , , cord-006870-f5w6fw6q 3664 27 seizures seizure NNS cord-006870-f5w6fw6q 3664 28 / / SYM cord-006870-f5w6fw6q 3664 29 status status NN cord-006870-f5w6fw6q 3664 30 epilepticus epilepticus NN cord-006870-f5w6fw6q 3664 31 ( ( -LRB- cord-006870-f5w6fw6q 3664 32 10 10 CD cord-006870-f5w6fw6q 3664 33 % % NN cord-006870-f5w6fw6q 3664 34 ) ) -RRB- cord-006870-f5w6fw6q 3664 35 and and CC cord-006870-f5w6fw6q 3664 36 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3664 37 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3664 38 ( ( -LRB- cord-006870-f5w6fw6q 3664 39 9 9 CD cord-006870-f5w6fw6q 3664 40 % % NN cord-006870-f5w6fw6q 3664 41 ) ) -RRB- cord-006870-f5w6fw6q 3664 42 . . . cord-006870-f5w6fw6q 3665 1 271 271 CD cord-006870-f5w6fw6q 3665 2 ( ( -LRB- cord-006870-f5w6fw6q 3665 3 25 25 CD cord-006870-f5w6fw6q 3665 4 % % NN cord-006870-f5w6fw6q 3665 5 ) ) -RRB- cord-006870-f5w6fw6q 3665 6 died die VBD cord-006870-f5w6fw6q 3665 7 in in IN cord-006870-f5w6fw6q 3665 8 the the DT cord-006870-f5w6fw6q 3665 9 hospital hospital NN cord-006870-f5w6fw6q 3665 10 ; ; : cord-006870-f5w6fw6q 3665 11 130 130 CD cord-006870-f5w6fw6q 3665 12 ( ( -LRB- cord-006870-f5w6fw6q 3665 13 12 12 CD cord-006870-f5w6fw6q 3665 14 % % NN cord-006870-f5w6fw6q 3665 15 ) ) -RRB- cord-006870-f5w6fw6q 3665 16 died die VBD cord-006870-f5w6fw6q 3665 17 by by IN cord-006870-f5w6fw6q 3665 18 follow follow NN cord-006870-f5w6fw6q 3665 19 - - HYPH cord-006870-f5w6fw6q 3665 20 up up NN cord-006870-f5w6fw6q 3665 21 . . . cord-006870-f5w6fw6q 3666 1 702 702 CD cord-006870-f5w6fw6q 3666 2 survivors survivor NNS cord-006870-f5w6fw6q 3666 3 were be VBD cord-006870-f5w6fw6q 3666 4 assessed assess VBN cord-006870-f5w6fw6q 3666 5 133.2+/-25.6 133.2+/-25.6 CD cord-006870-f5w6fw6q 3666 6 days day NNS cord-006870-f5w6fw6q 3666 7 following follow VBG cord-006870-f5w6fw6q 3666 8 admission admission NN cord-006870-f5w6fw6q 3666 9 . . . cord-006870-f5w6fw6q 3667 1 462 462 CD cord-006870-f5w6fw6q 3667 2 calls call NNS cord-006870-f5w6fw6q 3667 3 were be VBD cord-006870-f5w6fw6q 3667 4 answered answer VBN cord-006870-f5w6fw6q 3667 5 , , , cord-006870-f5w6fw6q 3667 6 231 231 CD cord-006870-f5w6fw6q 3667 7 were be VBD cord-006870-f5w6fw6q 3667 8 not not RB cord-006870-f5w6fw6q 3667 9 . . . cord-006870-f5w6fw6q 3668 1 There there EX cord-006870-f5w6fw6q 3668 2 were be VBD cord-006870-f5w6fw6q 3668 3 no no DT cord-006870-f5w6fw6q 3668 4 associations association NNS cord-006870-f5w6fw6q 3668 5 between between IN cord-006870-f5w6fw6q 3668 6 rate rate NN cord-006870-f5w6fw6q 3668 7 of of IN cord-006870-f5w6fw6q 3668 8 answered answer VBN cord-006870-f5w6fw6q 3668 9 calls call NNS cord-006870-f5w6fw6q 3668 10 and and CC cord-006870-f5w6fw6q 3668 11 age age NN cord-006870-f5w6fw6q 3668 12 , , , cord-006870-f5w6fw6q 3668 13 gender gender NN cord-006870-f5w6fw6q 3668 14 , , , cord-006870-f5w6fw6q 3668 15 race race NN cord-006870-f5w6fw6q 3668 16 , , , cord-006870-f5w6fw6q 3668 17 hospital hospital NN cord-006870-f5w6fw6q 3668 18 length length NN cord-006870-f5w6fw6q 3668 19 - - HYPH cord-006870-f5w6fw6q 3668 20 of of IN cord-006870-f5w6fw6q 3668 21 - - HYPH cord-006870-f5w6fw6q 3668 22 stay stay NN cord-006870-f5w6fw6q 3668 23 , , , cord-006870-f5w6fw6q 3668 24 diagnosis diagnosis NN cord-006870-f5w6fw6q 3668 25 , , , cord-006870-f5w6fw6q 3668 26 or or CC cord-006870-f5w6fw6q 3668 27 hospital hospital NN cord-006870-f5w6fw6q 3668 28 disposition disposition NN cord-006870-f5w6fw6q 3668 29 . . . cord-006870-f5w6fw6q 3669 1 There there EX cord-006870-f5w6fw6q 3669 2 were be VBD cord-006870-f5w6fw6q 3669 3 no no DT cord-006870-f5w6fw6q 3669 4 differences difference NNS cord-006870-f5w6fw6q 3669 5 in in IN cord-006870-f5w6fw6q 3669 6 between between IN cord-006870-f5w6fw6q 3669 7 morning morning NN cord-006870-f5w6fw6q 3669 8 vs. vs. IN cord-006870-f5w6fw6q 3669 9 afternoon afternoon NN cord-006870-f5w6fw6q 3669 10 calls call NNS cord-006870-f5w6fw6q 3669 11 . . . cord-006870-f5w6fw6q 3670 1 Only only RB cord-006870-f5w6fw6q 3670 2 the the DT cord-006870-f5w6fw6q 3670 3 number number NN cord-006870-f5w6fw6q 3670 4 of of IN cord-006870-f5w6fw6q 3670 5 attempts attempt NNS cord-006870-f5w6fw6q 3670 6 differed differ VBD cord-006870-f5w6fw6q 3670 7 : : : cord-006870-f5w6fw6q 3670 8 the the DT cord-006870-f5w6fw6q 3670 9 probability probability NN cord-006870-f5w6fw6q 3670 10 of of IN cord-006870-f5w6fw6q 3670 11 an an DT cord-006870-f5w6fw6q 3670 12 answered answer VBN cord-006870-f5w6fw6q 3670 13 call call NN cord-006870-f5w6fw6q 3670 14 was be VBD cord-006870-f5w6fw6q 3670 15 90 90 CD cord-006870-f5w6fw6q 3670 16 % % NN cord-006870-f5w6fw6q 3670 17 on on IN cord-006870-f5w6fw6q 3670 18 the the DT cord-006870-f5w6fw6q 3670 19 first first JJ cord-006870-f5w6fw6q 3670 20 attempt attempt NN cord-006870-f5w6fw6q 3670 21 but but CC cord-006870-f5w6fw6q 3670 22 declined decline VBD cord-006870-f5w6fw6q 3670 23 to to IN cord-006870-f5w6fw6q 3670 24 14 14 CD cord-006870-f5w6fw6q 3670 25 % % NN cord-006870-f5w6fw6q 3670 26 by by IN cord-006870-f5w6fw6q 3670 27 the the DT cord-006870-f5w6fw6q 3670 28 third third JJ cord-006870-f5w6fw6q 3670 29 attempt attempt NN cord-006870-f5w6fw6q 3670 30 ( ( -LRB- cord-006870-f5w6fw6q 3670 31 OR OR NNP cord-006870-f5w6fw6q 3670 32 0.13 0.13 CD cord-006870-f5w6fw6q 3670 33 ; ; : cord-006870-f5w6fw6q 3670 34 p<0.01 p<0.01 NNP cord-006870-f5w6fw6q 3670 35 ) ) -RRB- cord-006870-f5w6fw6q 3670 36 . . . cord-006870-f5w6fw6q 3671 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3671 2 outcome outcome NN cord-006870-f5w6fw6q 3671 3 assessment assessment NN cord-006870-f5w6fw6q 3671 4 strategy strategy NN cord-006870-f5w6fw6q 3671 5 captured capture VBD cord-006870-f5w6fw6q 3671 6 data datum NNS cord-006870-f5w6fw6q 3671 7 on on IN cord-006870-f5w6fw6q 3671 8 78 78 CD cord-006870-f5w6fw6q 3671 9 % % NN cord-006870-f5w6fw6q 3671 10 of of IN cord-006870-f5w6fw6q 3671 11 neurocritically neurocritically RB cord-006870-f5w6fw6q 3671 12 ill ill JJ cord-006870-f5w6fw6q 3671 13 patients patient NNS cord-006870-f5w6fw6q 3671 14 . . . cord-006870-f5w6fw6q 3672 1 Those those DT cord-006870-f5w6fw6q 3672 2 who who WP cord-006870-f5w6fw6q 3672 3 answer answer VBP cord-006870-f5w6fw6q 3672 4 the the DT cord-006870-f5w6fw6q 3672 5 phone phone NN cord-006870-f5w6fw6q 3672 6 are be VBP cord-006870-f5w6fw6q 3672 7 most most RBS cord-006870-f5w6fw6q 3672 8 likely likely JJ cord-006870-f5w6fw6q 3672 9 to to TO cord-006870-f5w6fw6q 3672 10 answer answer VB cord-006870-f5w6fw6q 3672 11 with with IN cord-006870-f5w6fw6q 3672 12 the the DT cord-006870-f5w6fw6q 3672 13 first first JJ cord-006870-f5w6fw6q 3672 14 call call NN cord-006870-f5w6fw6q 3672 15 ; ; : cord-006870-f5w6fw6q 3672 16 the the DT cord-006870-f5w6fw6q 3672 17 probability probability NN cord-006870-f5w6fw6q 3672 18 of of IN cord-006870-f5w6fw6q 3672 19 a a DT cord-006870-f5w6fw6q 3672 20 patient patient NN cord-006870-f5w6fw6q 3672 21 answering answer VBG cord-006870-f5w6fw6q 3672 22 after after IN cord-006870-f5w6fw6q 3672 23 a a DT cord-006870-f5w6fw6q 3672 24 second second JJ cord-006870-f5w6fw6q 3672 25 phone phone NN cord-006870-f5w6fw6q 3672 26 call call NN cord-006870-f5w6fw6q 3672 27 may may MD cord-006870-f5w6fw6q 3672 28 not not RB cord-006870-f5w6fw6q 3672 29 justify justify VB cord-006870-f5w6fw6q 3672 30 resources resource NNS cord-006870-f5w6fw6q 3672 31 needed need VBN cord-006870-f5w6fw6q 3672 32 to to TO cord-006870-f5w6fw6q 3672 33 continue continue VB cord-006870-f5w6fw6q 3672 34 calling call VBG cord-006870-f5w6fw6q 3672 35 these these DT cord-006870-f5w6fw6q 3672 36 patients patient NNS cord-006870-f5w6fw6q 3672 37 . . . cord-006870-f5w6fw6q 3673 1 Posterior posterior JJ cord-006870-f5w6fw6q 3673 2 reversible reversible JJ cord-006870-f5w6fw6q 3673 3 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 3673 4 syndrome syndrome NN cord-006870-f5w6fw6q 3673 5 ( ( -LRB- cord-006870-f5w6fw6q 3673 6 PRES PRES NNP cord-006870-f5w6fw6q 3673 7 ) ) -RRB- cord-006870-f5w6fw6q 3673 8 typically typically RB cord-006870-f5w6fw6q 3673 9 presents present VBZ cord-006870-f5w6fw6q 3673 10 with with IN cord-006870-f5w6fw6q 3673 11 vasogenic vasogenic NN cord-006870-f5w6fw6q 3673 12 edema edema NN cord-006870-f5w6fw6q 3673 13 on on IN cord-006870-f5w6fw6q 3673 14 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 3673 15 . . . cord-006870-f5w6fw6q 3674 1 A a DT cord-006870-f5w6fw6q 3674 2 subset subset NN cord-006870-f5w6fw6q 3674 3 of of IN cord-006870-f5w6fw6q 3674 4 patient patient NN cord-006870-f5w6fw6q 3674 5 , , , cord-006870-f5w6fw6q 3674 6 however however RB cord-006870-f5w6fw6q 3674 7 , , , cord-006870-f5w6fw6q 3674 8 can can MD cord-006870-f5w6fw6q 3674 9 have have VB cord-006870-f5w6fw6q 3674 10 " " `` cord-006870-f5w6fw6q 3674 11 atypical atypical JJ cord-006870-f5w6fw6q 3674 12 findings finding NNS cord-006870-f5w6fw6q 3674 13 " " '' cord-006870-f5w6fw6q 3674 14 including include VBG cord-006870-f5w6fw6q 3674 15 restricted restrict VBN cord-006870-f5w6fw6q 3674 16 diffusion diffusion NN cord-006870-f5w6fw6q 3674 17 and and CC cord-006870-f5w6fw6q 3674 18 intracranial intracranial JJ cord-006870-f5w6fw6q 3674 19 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3674 20 . . . cord-006870-f5w6fw6q 3675 1 These these DT cord-006870-f5w6fw6q 3675 2 atypical atypical JJ cord-006870-f5w6fw6q 3675 3 findings finding NNS cord-006870-f5w6fw6q 3675 4 all all DT cord-006870-f5w6fw6q 3675 5 suggest suggest VBP cord-006870-f5w6fw6q 3675 6 acute acute JJ cord-006870-f5w6fw6q 3675 7 vascular vascular JJ cord-006870-f5w6fw6q 3675 8 injury injury NN cord-006870-f5w6fw6q 3675 9 , , , cord-006870-f5w6fw6q 3675 10 and and CC cord-006870-f5w6fw6q 3675 11 may may MD cord-006870-f5w6fw6q 3675 12 mark mark VB cord-006870-f5w6fw6q 3675 13 a a DT cord-006870-f5w6fw6q 3675 14 distinct distinct JJ cord-006870-f5w6fw6q 3675 15 pathophysiological pathophysiological JJ cord-006870-f5w6fw6q 3675 16 subtype subtype NN cord-006870-f5w6fw6q 3675 17 of of IN cord-006870-f5w6fw6q 3675 18 PRES PRES NNP cord-006870-f5w6fw6q 3675 19 . . . cord-006870-f5w6fw6q 3676 1 However however RB cord-006870-f5w6fw6q 3676 2 , , , cord-006870-f5w6fw6q 3676 3 it -PRON- PRP cord-006870-f5w6fw6q 3676 4 is be VBZ cord-006870-f5w6fw6q 3676 5 unknown unknown JJ cord-006870-f5w6fw6q 3676 6 whether whether IN cord-006870-f5w6fw6q 3676 7 atypical atypical JJ cord-006870-f5w6fw6q 3676 8 imaging imaging NN cord-006870-f5w6fw6q 3676 9 findings finding NNS cord-006870-f5w6fw6q 3676 10 are be VBP cord-006870-f5w6fw6q 3676 11 associated associate VBN cord-006870-f5w6fw6q 3676 12 with with IN cord-006870-f5w6fw6q 3676 13 differences difference NNS cord-006870-f5w6fw6q 3676 14 in in IN cord-006870-f5w6fw6q 3676 15 precipitating precipitate VBG cord-006870-f5w6fw6q 3676 16 factors factor NNS cord-006870-f5w6fw6q 3676 17 or or CC cord-006870-f5w6fw6q 3676 18 outcome outcome NN cord-006870-f5w6fw6q 3676 19 . . . cord-006870-f5w6fw6q 3677 1 Patients patient NNS cord-006870-f5w6fw6q 3677 2 with with IN cord-006870-f5w6fw6q 3677 3 evidence evidence NN cord-006870-f5w6fw6q 3677 4 of of IN cord-006870-f5w6fw6q 3677 5 restricted restricted JJ cord-006870-f5w6fw6q 3677 6 diffusion diffusion NN cord-006870-f5w6fw6q 3677 7 , , , cord-006870-f5w6fw6q 3677 8 frank frank JJ cord-006870-f5w6fw6q 3677 9 hematoma hematoma NN cord-006870-f5w6fw6q 3677 10 , , , cord-006870-f5w6fw6q 3677 11 microhemorrhage microhemorrhage NN cord-006870-f5w6fw6q 3677 12 , , , cord-006870-f5w6fw6q 3677 13 or or CC cord-006870-f5w6fw6q 3677 14 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3677 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3677 16 were be VBD cord-006870-f5w6fw6q 3677 17 classified classify VBN cord-006870-f5w6fw6q 3677 18 as as IN cord-006870-f5w6fw6q 3677 19 having have VBG cord-006870-f5w6fw6q 3677 20 atypical atypical JJ cord-006870-f5w6fw6q 3677 21 imaging imaging NN cord-006870-f5w6fw6q 3677 22 findings finding NNS cord-006870-f5w6fw6q 3677 23 . . . cord-006870-f5w6fw6q 3678 1 The the DT cord-006870-f5w6fw6q 3678 2 demographics demographic NNS cord-006870-f5w6fw6q 3678 3 , , , cord-006870-f5w6fw6q 3678 4 risk risk NN cord-006870-f5w6fw6q 3678 5 factors factor NNS cord-006870-f5w6fw6q 3678 6 , , , cord-006870-f5w6fw6q 3678 7 clinical clinical JJ cord-006870-f5w6fw6q 3678 8 outcomes outcome NNS cord-006870-f5w6fw6q 3678 9 , , , cord-006870-f5w6fw6q 3678 10 and and CC cord-006870-f5w6fw6q 3678 11 degree degree NN cord-006870-f5w6fw6q 3678 12 of of IN cord-006870-f5w6fw6q 3678 13 vasogenic vasogenic NNP cord-006870-f5w6fw6q 3678 14 edema edema NN cord-006870-f5w6fw6q 3678 15 for for IN cord-006870-f5w6fw6q 3678 16 patients patient NNS cord-006870-f5w6fw6q 3678 17 with with IN cord-006870-f5w6fw6q 3678 18 typical typical JJ cord-006870-f5w6fw6q 3678 19 ( ( -LRB- cord-006870-f5w6fw6q 3678 20 n n NN cord-006870-f5w6fw6q 3678 21 = = SYM cord-006870-f5w6fw6q 3678 22 109 109 CD cord-006870-f5w6fw6q 3678 23 ) ) -RRB- cord-006870-f5w6fw6q 3678 24 vs vs IN cord-006870-f5w6fw6q 3678 25 atypical atypical JJ cord-006870-f5w6fw6q 3678 26 PRES PRES NNP cord-006870-f5w6fw6q 3678 27 findings finding NNS cord-006870-f5w6fw6q 3678 28 of of IN cord-006870-f5w6fw6q 3678 29 vascular vascular JJ cord-006870-f5w6fw6q 3678 30 injury injury NN cord-006870-f5w6fw6q 3678 31 ( ( -LRB- cord-006870-f5w6fw6q 3678 32 n n NN cord-006870-f5w6fw6q 3678 33 = = SYM cord-006870-f5w6fw6q 3678 34 75 75 CD cord-006870-f5w6fw6q 3678 35 ) ) -RRB- cord-006870-f5w6fw6q 3678 36 were be VBD cord-006870-f5w6fw6q 3678 37 analyzed analyze VBN cord-006870-f5w6fw6q 3678 38 . . . cord-006870-f5w6fw6q 3679 1 Patients patient NNS cord-006870-f5w6fw6q 3679 2 with with IN cord-006870-f5w6fw6q 3679 3 atypical atypical JJ cord-006870-f5w6fw6q 3679 4 PRES PRES NNP cord-006870-f5w6fw6q 3679 5 had have VBD cord-006870-f5w6fw6q 3679 6 a a DT cord-006870-f5w6fw6q 3679 7 longer long JJR cord-006870-f5w6fw6q 3679 8 hospital hospital NN cord-006870-f5w6fw6q 3679 9 stay stay NN cord-006870-f5w6fw6q 3679 10 ( ( -LRB- cord-006870-f5w6fw6q 3679 11 22.8 22.8 CD cord-006870-f5w6fw6q 3679 12 vs vs IN cord-006870-f5w6fw6q 3679 13 15.4 15.4 CD cord-006870-f5w6fw6q 3679 14 days day NNS cord-006870-f5w6fw6q 3679 15 ; ; : cord-006870-f5w6fw6q 3679 16 p p NN cord-006870-f5w6fw6q 3679 17 = = SYM cord-006870-f5w6fw6q 3679 18 0.039 0.039 CD cord-006870-f5w6fw6q 3679 19 ) ) -RRB- cord-006870-f5w6fw6q 3679 20 and and CC cord-006870-f5w6fw6q 3679 21 were be VBD cord-006870-f5w6fw6q 3679 22 less less RBR cord-006870-f5w6fw6q 3679 23 likely likely JJ cord-006870-f5w6fw6q 3679 24 to to TO cord-006870-f5w6fw6q 3679 25 be be VB cord-006870-f5w6fw6q 3679 26 discharged discharge VBN cord-006870-f5w6fw6q 3679 27 home home RB cord-006870-f5w6fw6q 3679 28 ( ( -LRB- cord-006870-f5w6fw6q 3679 29 54.7 54.7 CD cord-006870-f5w6fw6q 3679 30 % % NN cord-006870-f5w6fw6q 3679 31 vs vs IN cord-006870-f5w6fw6q 3679 32 69.7 69.7 CD cord-006870-f5w6fw6q 3679 33 % % NN cord-006870-f5w6fw6q 3679 34 ; ; : cord-006870-f5w6fw6q 3679 35 p p NN cord-006870-f5w6fw6q 3679 36 = = SYM cord-006870-f5w6fw6q 3679 37 0.036 0.036 CD cord-006870-f5w6fw6q 3679 38 ) ) -RRB- cord-006870-f5w6fw6q 3679 39 . . . cord-006870-f5w6fw6q 3680 1 Severity severity NN cord-006870-f5w6fw6q 3680 2 of of IN cord-006870-f5w6fw6q 3680 3 vasogenic vasogenic NNP cord-006870-f5w6fw6q 3680 4 edema edema NN cord-006870-f5w6fw6q 3680 5 ( ( -LRB- cord-006870-f5w6fw6q 3680 6 graded grade VBN cord-006870-f5w6fw6q 3680 7 using use VBG cord-006870-f5w6fw6q 3680 8 a a DT cord-006870-f5w6fw6q 3680 9 standardized standardized JJ cord-006870-f5w6fw6q 3680 10 radiologic radiologic JJ cord-006870-f5w6fw6q 3680 11 scale scale NN cord-006870-f5w6fw6q 3680 12 ) ) -RRB- cord-006870-f5w6fw6q 3680 13 was be VBD cord-006870-f5w6fw6q 3680 14 also also RB cord-006870-f5w6fw6q 3680 15 higher high JJR cord-006870-f5w6fw6q 3680 16 in in IN cord-006870-f5w6fw6q 3680 17 patients patient NNS cord-006870-f5w6fw6q 3680 18 with with IN cord-006870-f5w6fw6q 3680 19 atypical atypical JJ cord-006870-f5w6fw6q 3680 20 imaging imaging NN cord-006870-f5w6fw6q 3680 21 findings finding NNS cord-006870-f5w6fw6q 3680 22 ( ( -LRB- cord-006870-f5w6fw6q 3680 23 severe severe JJ cord-006870-f5w6fw6q 3680 24 edema edema NN cord-006870-f5w6fw6q 3680 25 : : : cord-006870-f5w6fw6q 3680 26 41.3 41.3 CD cord-006870-f5w6fw6q 3680 27 % % NN cord-006870-f5w6fw6q 3680 28 vs vs IN cord-006870-f5w6fw6q 3680 29 21.1 21.1 CD cord-006870-f5w6fw6q 3680 30 % % NN cord-006870-f5w6fw6q 3680 31 ; ; : cord-006870-f5w6fw6q 3680 32 p p NN cord-006870-f5w6fw6q 3680 33 = = SYM cord-006870-f5w6fw6q 3680 34 0.003 0.003 CD cord-006870-f5w6fw6q 3680 35 ) ) -RRB- cord-006870-f5w6fw6q 3680 36 . . . cord-006870-f5w6fw6q 3681 1 Restricted restricted JJ cord-006870-f5w6fw6q 3681 2 diffusion diffusion NN cord-006870-f5w6fw6q 3681 3 and and CC cord-006870-f5w6fw6q 3681 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3681 5 are be VBP cord-006870-f5w6fw6q 3681 6 features feature NNS cord-006870-f5w6fw6q 3681 7 of of IN cord-006870-f5w6fw6q 3681 8 acute acute JJ cord-006870-f5w6fw6q 3681 9 vascular vascular JJ cord-006870-f5w6fw6q 3681 10 injury injury NN cord-006870-f5w6fw6q 3681 11 that that WDT cord-006870-f5w6fw6q 3681 12 may may MD cord-006870-f5w6fw6q 3681 13 mark mark VB cord-006870-f5w6fw6q 3681 14 a a DT cord-006870-f5w6fw6q 3681 15 unique unique JJ cord-006870-f5w6fw6q 3681 16 pathophysiological pathophysiological JJ cord-006870-f5w6fw6q 3681 17 subtype subtype NN cord-006870-f5w6fw6q 3681 18 of of IN cord-006870-f5w6fw6q 3681 19 PRES PRES NNP cord-006870-f5w6fw6q 3681 20 . . . cord-006870-f5w6fw6q 3682 1 PRES PRES NNP cord-006870-f5w6fw6q 3682 2 patients patient NNS cord-006870-f5w6fw6q 3682 3 with with IN cord-006870-f5w6fw6q 3682 4 these these DT cord-006870-f5w6fw6q 3682 5 atypical atypical JJ cord-006870-f5w6fw6q 3682 6 imaging imaging NN cord-006870-f5w6fw6q 3682 7 features feature NNS cord-006870-f5w6fw6q 3682 8 had have VBD cord-006870-f5w6fw6q 3682 9 longer long JJR cord-006870-f5w6fw6q 3682 10 hospital hospital NN cord-006870-f5w6fw6q 3682 11 stays stay NNS cord-006870-f5w6fw6q 3682 12 , , , cord-006870-f5w6fw6q 3682 13 greater great JJR cord-006870-f5w6fw6q 3682 14 degree degree NN cord-006870-f5w6fw6q 3682 15 of of IN cord-006870-f5w6fw6q 3682 16 vasogenic vasogenic NNP cord-006870-f5w6fw6q 3682 17 edema edema NN cord-006870-f5w6fw6q 3682 18 , , , cord-006870-f5w6fw6q 3682 19 and and CC cord-006870-f5w6fw6q 3682 20 were be VBD cord-006870-f5w6fw6q 3682 21 less less RBR cord-006870-f5w6fw6q 3682 22 likely likely JJ cord-006870-f5w6fw6q 3682 23 to to TO cord-006870-f5w6fw6q 3682 24 be be VB cord-006870-f5w6fw6q 3682 25 discharged discharge VBN cord-006870-f5w6fw6q 3682 26 home home RB cord-006870-f5w6fw6q 3682 27 . . . cord-006870-f5w6fw6q 3683 1 This this DT cord-006870-f5w6fw6q 3683 2 may may MD cord-006870-f5w6fw6q 3683 3 be be VB cord-006870-f5w6fw6q 3683 4 due due JJ cord-006870-f5w6fw6q 3683 5 to to IN cord-006870-f5w6fw6q 3683 6 the the DT cord-006870-f5w6fw6q 3683 7 fact fact NN cord-006870-f5w6fw6q 3683 8 that that IN cord-006870-f5w6fw6q 3683 9 bleeding bleeding NN cord-006870-f5w6fw6q 3683 10 and and CC cord-006870-f5w6fw6q 3683 11 infarction infarction NN cord-006870-f5w6fw6q 3683 12 lead lead NN cord-006870-f5w6fw6q 3683 13 to to IN cord-006870-f5w6fw6q 3683 14 irreversible irreversible JJ cord-006870-f5w6fw6q 3683 15 brain brain NN cord-006870-f5w6fw6q 3683 16 injury injury NN cord-006870-f5w6fw6q 3683 17 , , , cord-006870-f5w6fw6q 3683 18 prolonging prolong VBG cord-006870-f5w6fw6q 3683 19 hospital hospital NN cord-006870-f5w6fw6q 3683 20 stay stay NN cord-006870-f5w6fw6q 3683 21 and and CC cord-006870-f5w6fw6q 3683 22 contributing contribute VBG cord-006870-f5w6fw6q 3683 23 to to IN cord-006870-f5w6fw6q 3683 24 overall overall JJ cord-006870-f5w6fw6q 3683 25 disability disability NN cord-006870-f5w6fw6q 3683 26 . . . cord-006870-f5w6fw6q 3684 1 In in IN cord-006870-f5w6fw6q 3684 2 2016 2016 CD cord-006870-f5w6fw6q 3684 3 , , , cord-006870-f5w6fw6q 3684 4 16 16 CD cord-006870-f5w6fw6q 3684 5 deaths death NNS cord-006870-f5w6fw6q 3684 6 occurred occur VBD cord-006870-f5w6fw6q 3684 7 in in IN cord-006870-f5w6fw6q 3684 8 the the DT cord-006870-f5w6fw6q 3684 9 neuro neuro NNP cord-006870-f5w6fw6q 3684 10 - - HYPH cord-006870-f5w6fw6q 3684 11 oncologic oncologic JJ cord-006870-f5w6fw6q 3684 12 critical critical JJ cord-006870-f5w6fw6q 3684 13 care care NN cord-006870-f5w6fw6q 3684 14 unit unit NN cord-006870-f5w6fw6q 3684 15 ( ( -LRB- cord-006870-f5w6fw6q 3684 16 NCCU NCCU NNP cord-006870-f5w6fw6q 3684 17 ) ) -RRB- cord-006870-f5w6fw6q 3684 18 . . . cord-006870-f5w6fw6q 3685 1 The the DT cord-006870-f5w6fw6q 3685 2 impact impact NN cord-006870-f5w6fw6q 3685 3 of of IN cord-006870-f5w6fw6q 3685 4 this this DT cord-006870-f5w6fw6q 3685 5 event event NN cord-006870-f5w6fw6q 3685 6 is be VBZ cord-006870-f5w6fw6q 3685 7 significant significant JJ cord-006870-f5w6fw6q 3685 8 for for IN cord-006870-f5w6fw6q 3685 9 patients patient NNS cord-006870-f5w6fw6q 3685 10 , , , cord-006870-f5w6fw6q 3685 11 families family NNS cord-006870-f5w6fw6q 3685 12 , , , cord-006870-f5w6fw6q 3685 13 and and CC cord-006870-f5w6fw6q 3685 14 the the DT cord-006870-f5w6fw6q 3685 15 staff staff NN cord-006870-f5w6fw6q 3685 16 that that WDT cord-006870-f5w6fw6q 3685 17 care care VBP cord-006870-f5w6fw6q 3685 18 for for IN cord-006870-f5w6fw6q 3685 19 them -PRON- PRP cord-006870-f5w6fw6q 3685 20 . . . cord-006870-f5w6fw6q 3686 1 Brain brain NN cord-006870-f5w6fw6q 3686 2 and and CC cord-006870-f5w6fw6q 3686 3 spinal spinal JJ cord-006870-f5w6fw6q 3686 4 pathology pathology NN cord-006870-f5w6fw6q 3686 5 can can MD cord-006870-f5w6fw6q 3686 6 be be VB cord-006870-f5w6fw6q 3686 7 incredibly incredibly RB cord-006870-f5w6fw6q 3686 8 debilitating debilitating JJ cord-006870-f5w6fw6q 3686 9 causing cause VBG cord-006870-f5w6fw6q 3686 10 a a DT cord-006870-f5w6fw6q 3686 11 rapid rapid JJ cord-006870-f5w6fw6q 3686 12 and and CC cord-006870-f5w6fw6q 3686 13 impromptu impromptu JJ cord-006870-f5w6fw6q 3686 14 decline decline NN cord-006870-f5w6fw6q 3686 15 of of IN cord-006870-f5w6fw6q 3686 16 the the DT cord-006870-f5w6fw6q 3686 17 patient patient NN cord-006870-f5w6fw6q 3686 18 's 's POS cord-006870-f5w6fw6q 3686 19 status status NN cord-006870-f5w6fw6q 3686 20 . . . cord-006870-f5w6fw6q 3687 1 In in IN cord-006870-f5w6fw6q 3687 2 order order NN cord-006870-f5w6fw6q 3687 3 to to TO cord-006870-f5w6fw6q 3687 4 better well JJR cord-006870-f5w6fw6q 3687 5 support support NN cord-006870-f5w6fw6q 3687 6 patients patient NNS cord-006870-f5w6fw6q 3687 7 , , , cord-006870-f5w6fw6q 3687 8 family family NN cord-006870-f5w6fw6q 3687 9 , , , cord-006870-f5w6fw6q 3687 10 and and CC cord-006870-f5w6fw6q 3687 11 staff staff NN cord-006870-f5w6fw6q 3687 12 throughout throughout IN cord-006870-f5w6fw6q 3687 13 the the DT cord-006870-f5w6fw6q 3687 14 dying die VBG cord-006870-f5w6fw6q 3687 15 process process NN cord-006870-f5w6fw6q 3687 16 , , , cord-006870-f5w6fw6q 3687 17 the the DT cord-006870-f5w6fw6q 3687 18 NCCU NCCU NNP cord-006870-f5w6fw6q 3687 19 staff staff NN cord-006870-f5w6fw6q 3687 20 created create VBN cord-006870-f5w6fw6q 3687 21 formalized formalize VBN cord-006870-f5w6fw6q 3687 22 endof endof NN cord-006870-f5w6fw6q 3687 23 - - HYPH cord-006870-f5w6fw6q 3687 24 life life NN cord-006870-f5w6fw6q 3687 25 care care NN cord-006870-f5w6fw6q 3687 26 interventions intervention NNS cord-006870-f5w6fw6q 3687 27 . . . cord-006870-f5w6fw6q 3688 1 These these DT cord-006870-f5w6fw6q 3688 2 interventions intervention NNS cord-006870-f5w6fw6q 3688 3 include include VBP cord-006870-f5w6fw6q 3688 4 educational educational JJ cord-006870-f5w6fw6q 3688 5 pieces piece NNS cord-006870-f5w6fw6q 3688 6 and and CC cord-006870-f5w6fw6q 3688 7 supportive supportive JJ cord-006870-f5w6fw6q 3688 8 approaches approach NNS cord-006870-f5w6fw6q 3688 9 to to TO cord-006870-f5w6fw6q 3688 10 aid aid VB cord-006870-f5w6fw6q 3688 11 all all DT cord-006870-f5w6fw6q 3688 12 involved involve VBN cord-006870-f5w6fw6q 3688 13 through through IN cord-006870-f5w6fw6q 3688 14 the the DT cord-006870-f5w6fw6q 3688 15 dying die VBG cord-006870-f5w6fw6q 3688 16 process process NN cord-006870-f5w6fw6q 3688 17 . . . cord-006870-f5w6fw6q 3689 1 Several several JJ cord-006870-f5w6fw6q 3689 2 interventions intervention NNS cord-006870-f5w6fw6q 3689 3 were be VBD cord-006870-f5w6fw6q 3689 4 created create VBN cord-006870-f5w6fw6q 3689 5 to to TO cord-006870-f5w6fw6q 3689 6 help help VB cord-006870-f5w6fw6q 3689 7 transition transition VB cord-006870-f5w6fw6q 3689 8 the the DT cord-006870-f5w6fw6q 3689 9 family family NN cord-006870-f5w6fw6q 3689 10 members member NNS cord-006870-f5w6fw6q 3689 11 during during IN cord-006870-f5w6fw6q 3689 12 the the DT cord-006870-f5w6fw6q 3689 13 dying die VBG cord-006870-f5w6fw6q 3689 14 process process NN cord-006870-f5w6fw6q 3689 15 . . . cord-006870-f5w6fw6q 3690 1 These these DT cord-006870-f5w6fw6q 3690 2 include include VBP cord-006870-f5w6fw6q 3690 3 the the DT cord-006870-f5w6fw6q 3690 4 creation creation NN cord-006870-f5w6fw6q 3690 5 of of IN cord-006870-f5w6fw6q 3690 6 : : : cord-006870-f5w6fw6q 3690 7 DNR DNR NNP cord-006870-f5w6fw6q 3690 8 - - HYPH cord-006870-f5w6fw6q 3690 9 CC CC NNP cord-006870-f5w6fw6q 3690 10 closet closet NN cord-006870-f5w6fw6q 3690 11 , , , cord-006870-f5w6fw6q 3690 12 homemade homemade JJ cord-006870-f5w6fw6q 3690 13 blankets blanket NNS cord-006870-f5w6fw6q 3690 14 , , , cord-006870-f5w6fw6q 3690 15 condolence condolence NN cord-006870-f5w6fw6q 3690 16 cards card NNS cord-006870-f5w6fw6q 3690 17 , , , cord-006870-f5w6fw6q 3690 18 hygiene hygiene NN cord-006870-f5w6fw6q 3690 19 bags bag NNS cord-006870-f5w6fw6q 3690 20 , , , cord-006870-f5w6fw6q 3690 21 educational educational JJ cord-006870-f5w6fw6q 3690 22 packets packet NNS cord-006870-f5w6fw6q 3690 23 , , , cord-006870-f5w6fw6q 3690 24 Word Word NNP cord-006870-f5w6fw6q 3690 25 Clouds Clouds NNPS cord-006870-f5w6fw6q 3690 26 , , , cord-006870-f5w6fw6q 3690 27 and and CC cord-006870-f5w6fw6q 3690 28 aromatherapies aromatherapy NNS cord-006870-f5w6fw6q 3690 29 and and CC cord-006870-f5w6fw6q 3690 30 massage massage NN cord-006870-f5w6fw6q 3690 31 items item NNS cord-006870-f5w6fw6q 3690 32 . . . cord-006870-f5w6fw6q 3691 1 Once once IN cord-006870-f5w6fw6q 3691 2 the the DT cord-006870-f5w6fw6q 3691 3 patient patient NN cord-006870-f5w6fw6q 3691 4 's 's POS cord-006870-f5w6fw6q 3691 5 code code NN cord-006870-f5w6fw6q 3691 6 status status NN cord-006870-f5w6fw6q 3691 7 is be VBZ cord-006870-f5w6fw6q 3691 8 changed change VBN cord-006870-f5w6fw6q 3691 9 to to TO cord-006870-f5w6fw6q 3691 10 comfort comfort NN cord-006870-f5w6fw6q 3691 11 care care NN cord-006870-f5w6fw6q 3691 12 , , , cord-006870-f5w6fw6q 3691 13 a a DT cord-006870-f5w6fw6q 3691 14 blanket blanket NN cord-006870-f5w6fw6q 3691 15 is be VBZ cord-006870-f5w6fw6q 3691 16 given give VBN cord-006870-f5w6fw6q 3691 17 to to IN cord-006870-f5w6fw6q 3691 18 the the DT cord-006870-f5w6fw6q 3691 19 patient patient NN cord-006870-f5w6fw6q 3691 20 . . . cord-006870-f5w6fw6q 3692 1 Family family NN cord-006870-f5w6fw6q 3692 2 members member NNS cord-006870-f5w6fw6q 3692 3 are be VBP cord-006870-f5w6fw6q 3692 4 provided provide VBN cord-006870-f5w6fw6q 3692 5 with with IN cord-006870-f5w6fw6q 3692 6 a a DT cord-006870-f5w6fw6q 3692 7 bag bag NN cord-006870-f5w6fw6q 3692 8 of of IN cord-006870-f5w6fw6q 3692 9 toiletries toiletry NNS cord-006870-f5w6fw6q 3692 10 for for IN cord-006870-f5w6fw6q 3692 11 those those DT cord-006870-f5w6fw6q 3692 12 that that WDT cord-006870-f5w6fw6q 3692 13 remain remain VBP cord-006870-f5w6fw6q 3692 14 at at IN cord-006870-f5w6fw6q 3692 15 bedside bedside NN cord-006870-f5w6fw6q 3692 16 . . . cord-006870-f5w6fw6q 3693 1 Education education NN cord-006870-f5w6fw6q 3693 2 on on IN cord-006870-f5w6fw6q 3693 3 the the DT cord-006870-f5w6fw6q 3693 4 dying dying NN cord-006870-f5w6fw6q 3693 5 process process NN cord-006870-f5w6fw6q 3693 6 are be VBP cord-006870-f5w6fw6q 3693 7 given give VBN cord-006870-f5w6fw6q 3693 8 to to IN cord-006870-f5w6fw6q 3693 9 family family NN cord-006870-f5w6fw6q 3693 10 members member NNS cord-006870-f5w6fw6q 3693 11 . . . cord-006870-f5w6fw6q 3694 1 Multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 3694 2 resources resource NNS cord-006870-f5w6fw6q 3694 3 are be VBP cord-006870-f5w6fw6q 3694 4 provided provide VBN cord-006870-f5w6fw6q 3694 5 , , , cord-006870-f5w6fw6q 3694 6 such such JJ cord-006870-f5w6fw6q 3694 7 as as IN cord-006870-f5w6fw6q 3694 8 religious religious JJ cord-006870-f5w6fw6q 3694 9 support support NN cord-006870-f5w6fw6q 3694 10 focused focus VBD cord-006870-f5w6fw6q 3694 11 on on IN cord-006870-f5w6fw6q 3694 12 patient patient NN cord-006870-f5w6fw6q 3694 13 / / SYM cord-006870-f5w6fw6q 3694 14 family family NN cord-006870-f5w6fw6q 3694 15 beliefs belief NNS cord-006870-f5w6fw6q 3694 16 , , , cord-006870-f5w6fw6q 3694 17 palliative palliative JJ cord-006870-f5w6fw6q 3694 18 care care NN cord-006870-f5w6fw6q 3694 19 for for IN cord-006870-f5w6fw6q 3694 20 symptom symptom NN cord-006870-f5w6fw6q 3694 21 management management NN cord-006870-f5w6fw6q 3694 22 , , , cord-006870-f5w6fw6q 3694 23 and and CC cord-006870-f5w6fw6q 3694 24 dietary dietary JJ cord-006870-f5w6fw6q 3694 25 provision provision NN cord-006870-f5w6fw6q 3694 26 of of IN cord-006870-f5w6fw6q 3694 27 light light JJ cord-006870-f5w6fw6q 3694 28 snacks snack NNS cord-006870-f5w6fw6q 3694 29 to to IN cord-006870-f5w6fw6q 3694 30 the the DT cord-006870-f5w6fw6q 3694 31 family family NN cord-006870-f5w6fw6q 3694 32 . . . cord-006870-f5w6fw6q 3695 1 Education education NN cord-006870-f5w6fw6q 3695 2 for for IN cord-006870-f5w6fw6q 3695 3 the the DT cord-006870-f5w6fw6q 3695 4 physicians physician NNS cord-006870-f5w6fw6q 3695 5 , , , cord-006870-f5w6fw6q 3695 6 nurse nurse NN cord-006870-f5w6fw6q 3695 7 practitioners practitioner NNS cord-006870-f5w6fw6q 3695 8 , , , cord-006870-f5w6fw6q 3695 9 nurses nurse NNS cord-006870-f5w6fw6q 3695 10 , , , cord-006870-f5w6fw6q 3695 11 and and CC cord-006870-f5w6fw6q 3695 12 patient patient JJ cord-006870-f5w6fw6q 3695 13 care care NN cord-006870-f5w6fw6q 3695 14 associates associate NNS cord-006870-f5w6fw6q 3695 15 was be VBD cord-006870-f5w6fw6q 3695 16 provided provide VBN cord-006870-f5w6fw6q 3695 17 for for IN cord-006870-f5w6fw6q 3695 18 those those DT cord-006870-f5w6fw6q 3695 19 who who WP cord-006870-f5w6fw6q 3695 20 wished wish VBD cord-006870-f5w6fw6q 3695 21 to to TO cord-006870-f5w6fw6q 3695 22 attend attend VB cord-006870-f5w6fw6q 3695 23 to to TO cord-006870-f5w6fw6q 3695 24 further further RB cord-006870-f5w6fw6q 3695 25 understand understand VB cord-006870-f5w6fw6q 3695 26 this this DT cord-006870-f5w6fw6q 3695 27 end end NN cord-006870-f5w6fw6q 3695 28 of of IN cord-006870-f5w6fw6q 3695 29 life life NN cord-006870-f5w6fw6q 3695 30 care care NN cord-006870-f5w6fw6q 3695 31 program program NN cord-006870-f5w6fw6q 3695 32 . . . cord-006870-f5w6fw6q 3696 1 A a DT cord-006870-f5w6fw6q 3696 2 29 29 CD cord-006870-f5w6fw6q 3696 3 item item NN cord-006870-f5w6fw6q 3696 4 tool tool NN cord-006870-f5w6fw6q 3696 5 was be VBD cord-006870-f5w6fw6q 3696 6 created create VBN cord-006870-f5w6fw6q 3696 7 to to TO cord-006870-f5w6fw6q 3696 8 collect collect VB cord-006870-f5w6fw6q 3696 9 before before IN cord-006870-f5w6fw6q 3696 10 and and CC cord-006870-f5w6fw6q 3696 11 after after IN cord-006870-f5w6fw6q 3696 12 data datum NNS cord-006870-f5w6fw6q 3696 13 on on IN cord-006870-f5w6fw6q 3696 14 staff staff NN cord-006870-f5w6fw6q 3696 15 satisfaction satisfaction NN cord-006870-f5w6fw6q 3696 16 and and CC cord-006870-f5w6fw6q 3696 17 comfort comfort NN cord-006870-f5w6fw6q 3696 18 with with IN cord-006870-f5w6fw6q 3696 19 the the DT cord-006870-f5w6fw6q 3696 20 end end NN cord-006870-f5w6fw6q 3696 21 of of IN cord-006870-f5w6fw6q 3696 22 life life NN cord-006870-f5w6fw6q 3696 23 process process NN cord-006870-f5w6fw6q 3696 24 . . . cord-006870-f5w6fw6q 3697 1 Results result NNS cord-006870-f5w6fw6q 3697 2 from from IN cord-006870-f5w6fw6q 3697 3 this this DT cord-006870-f5w6fw6q 3697 4 process process NN cord-006870-f5w6fw6q 3697 5 are be VBP cord-006870-f5w6fw6q 3697 6 currently currently RB cord-006870-f5w6fw6q 3697 7 in in IN cord-006870-f5w6fw6q 3697 8 process process NN cord-006870-f5w6fw6q 3697 9 . . . cord-006870-f5w6fw6q 3698 1 Creating create VBG cord-006870-f5w6fw6q 3698 2 specific specific JJ cord-006870-f5w6fw6q 3698 3 end end NN cord-006870-f5w6fw6q 3698 4 - - HYPH cord-006870-f5w6fw6q 3698 5 of of IN cord-006870-f5w6fw6q 3698 6 - - HYPH cord-006870-f5w6fw6q 3698 7 life life NN cord-006870-f5w6fw6q 3698 8 care care NN cord-006870-f5w6fw6q 3698 9 interventions intervention NNS cord-006870-f5w6fw6q 3698 10 for for IN cord-006870-f5w6fw6q 3698 11 the the DT cord-006870-f5w6fw6q 3698 12 NCCU NCCU NNP cord-006870-f5w6fw6q 3698 13 have have VBP cord-006870-f5w6fw6q 3698 14 enabled enable VBN cord-006870-f5w6fw6q 3698 15 staff staff NN cord-006870-f5w6fw6q 3698 16 to to TO cord-006870-f5w6fw6q 3698 17 better well JJR cord-006870-f5w6fw6q 3698 18 care care VB cord-006870-f5w6fw6q 3698 19 for for IN cord-006870-f5w6fw6q 3698 20 patients patient NNS cord-006870-f5w6fw6q 3698 21 and and CC cord-006870-f5w6fw6q 3698 22 families family NNS cord-006870-f5w6fw6q 3698 23 . . . cord-006870-f5w6fw6q 3699 1 Through through IN cord-006870-f5w6fw6q 3699 2 the the DT cord-006870-f5w6fw6q 3699 3 creation creation NN cord-006870-f5w6fw6q 3699 4 of of IN cord-006870-f5w6fw6q 3699 5 the the DT cord-006870-f5w6fw6q 3699 6 interventions intervention NNS cord-006870-f5w6fw6q 3699 7 and and CC cord-006870-f5w6fw6q 3699 8 utilization utilization NN cord-006870-f5w6fw6q 3699 9 of of IN cord-006870-f5w6fw6q 3699 10 the the DT cord-006870-f5w6fw6q 3699 11 DNR DNR NNP cord-006870-f5w6fw6q 3699 12 - - HYPH cord-006870-f5w6fw6q 3699 13 CC CC NNP cord-006870-f5w6fw6q 3699 14 closet closet NN cord-006870-f5w6fw6q 3699 15 , , , cord-006870-f5w6fw6q 3699 16 this this DT cord-006870-f5w6fw6q 3699 17 unit unit NN cord-006870-f5w6fw6q 3699 18 has have VBZ cord-006870-f5w6fw6q 3699 19 been be VBN cord-006870-f5w6fw6q 3699 20 able able JJ cord-006870-f5w6fw6q 3699 21 to to TO cord-006870-f5w6fw6q 3699 22 better better RB cord-006870-f5w6fw6q 3699 23 provide provide VB cord-006870-f5w6fw6q 3699 24 comprehensive comprehensive JJ cord-006870-f5w6fw6q 3699 25 education education NN cord-006870-f5w6fw6q 3699 26 and and CC cord-006870-f5w6fw6q 3699 27 supportive supportive JJ cord-006870-f5w6fw6q 3699 28 pieces piece NNS cord-006870-f5w6fw6q 3699 29 to to IN cord-006870-f5w6fw6q 3699 30 patients patient NNS cord-006870-f5w6fw6q 3699 31 and and CC cord-006870-f5w6fw6q 3699 32 family family NN cord-006870-f5w6fw6q 3699 33 members member NNS cord-006870-f5w6fw6q 3699 34 during during IN cord-006870-f5w6fw6q 3699 35 such such PDT cord-006870-f5w6fw6q 3699 36 a a DT cord-006870-f5w6fw6q 3699 37 difficult difficult JJ cord-006870-f5w6fw6q 3699 38 time time NN cord-006870-f5w6fw6q 3699 39 . . . cord-006870-f5w6fw6q 3700 1 Delirium delirium NN cord-006870-f5w6fw6q 3700 2 is be VBZ cord-006870-f5w6fw6q 3700 3 a a DT cord-006870-f5w6fw6q 3700 4 neuropsychiatric neuropsychiatric JJ cord-006870-f5w6fw6q 3700 5 syndrome syndrome NN cord-006870-f5w6fw6q 3700 6 , , , cord-006870-f5w6fw6q 3700 7 characterized characterize VBN cord-006870-f5w6fw6q 3700 8 by by IN cord-006870-f5w6fw6q 3700 9 disturbance disturbance NN cord-006870-f5w6fw6q 3700 10 in in IN cord-006870-f5w6fw6q 3700 11 awareness awareness NN cord-006870-f5w6fw6q 3700 12 , , , cord-006870-f5w6fw6q 3700 13 with with IN cord-006870-f5w6fw6q 3700 14 reduced reduce VBN cord-006870-f5w6fw6q 3700 15 ability ability NN cord-006870-f5w6fw6q 3700 16 to to TO cord-006870-f5w6fw6q 3700 17 sustain sustain VB cord-006870-f5w6fw6q 3700 18 attention attention NN cord-006870-f5w6fw6q 3700 19 , , , cord-006870-f5w6fw6q 3700 20 impaired impair VBN cord-006870-f5w6fw6q 3700 21 cognition cognition NN cord-006870-f5w6fw6q 3700 22 , , , cord-006870-f5w6fw6q 3700 23 perception perception NN cord-006870-f5w6fw6q 3700 24 , , , cord-006870-f5w6fw6q 3700 25 tends tend VBZ cord-006870-f5w6fw6q 3700 26 to to TO cord-006870-f5w6fw6q 3700 27 fluctuate fluctuate VB cord-006870-f5w6fw6q 3700 28 in in IN cord-006870-f5w6fw6q 3700 29 severity severity NN cord-006870-f5w6fw6q 3700 30 during during IN cord-006870-f5w6fw6q 3700 31 the the DT cord-006870-f5w6fw6q 3700 32 day day NN cord-006870-f5w6fw6q 3700 33 ; ; : cord-006870-f5w6fw6q 3700 34 In in IN cord-006870-f5w6fw6q 3700 35 critical critical JJ cord-006870-f5w6fw6q 3700 36 care care NN cord-006870-f5w6fw6q 3700 37 is be VBZ cord-006870-f5w6fw6q 3700 38 associated associate VBN cord-006870-f5w6fw6q 3700 39 with with IN cord-006870-f5w6fw6q 3700 40 longer long JJR cord-006870-f5w6fw6q 3700 41 stay stay VB cord-006870-f5w6fw6q 3700 42 and and CC cord-006870-f5w6fw6q 3700 43 increase increase VB cord-006870-f5w6fw6q 3700 44 mortality mortality NN cord-006870-f5w6fw6q 3700 45 . . . cord-006870-f5w6fw6q 3701 1 This this DT cord-006870-f5w6fw6q 3701 2 study study NN cord-006870-f5w6fw6q 3701 3 aimed aim VBD cord-006870-f5w6fw6q 3701 4 to to TO cord-006870-f5w6fw6q 3701 5 determine determine VB cord-006870-f5w6fw6q 3701 6 the the DT cord-006870-f5w6fw6q 3701 7 incidence incidence NN cord-006870-f5w6fw6q 3701 8 , , , cord-006870-f5w6fw6q 3701 9 prevalence prevalence NN cord-006870-f5w6fw6q 3701 10 , , , cord-006870-f5w6fw6q 3701 11 predictors predictor NNS cord-006870-f5w6fw6q 3701 12 , , , cord-006870-f5w6fw6q 3701 13 risk risk NN cord-006870-f5w6fw6q 3701 14 factors factor NNS cord-006870-f5w6fw6q 3701 15 and and CC cord-006870-f5w6fw6q 3701 16 outcomes outcome NNS cord-006870-f5w6fw6q 3701 17 of of IN cord-006870-f5w6fw6q 3701 18 delirium delirium NN cord-006870-f5w6fw6q 3701 19 in in IN cord-006870-f5w6fw6q 3701 20 Critically critically RB cord-006870-f5w6fw6q 3701 21 ill ill JJ cord-006870-f5w6fw6q 3701 22 Adult adult NN cord-006870-f5w6fw6q 3701 23 . . . cord-006870-f5w6fw6q 3702 1 A a DT cord-006870-f5w6fw6q 3702 2 historical historical JJ cord-006870-f5w6fw6q 3702 3 cohort cohort NN cord-006870-f5w6fw6q 3702 4 study study NN cord-006870-f5w6fw6q 3702 5 was be VBD cord-006870-f5w6fw6q 3702 6 conducted conduct VBN cord-006870-f5w6fw6q 3702 7 in in IN cord-006870-f5w6fw6q 3702 8 adult adult NN cord-006870-f5w6fw6q 3702 9 patients patient NNS cord-006870-f5w6fw6q 3702 10 hospitalized hospitalize VBN cord-006870-f5w6fw6q 3702 11 in in IN cord-006870-f5w6fw6q 3702 12 a a DT cord-006870-f5w6fw6q 3702 13 polyvalent polyvalent JJ cord-006870-f5w6fw6q 3702 14 ICU icu NN cord-006870-f5w6fw6q 3702 15 from from IN cord-006870-f5w6fw6q 3702 16 January January NNP cord-006870-f5w6fw6q 3702 17 2016 2016 CD cord-006870-f5w6fw6q 3702 18 until until IN cord-006870-f5w6fw6q 3702 19 December December NNP cord-006870-f5w6fw6q 3702 20 2016 2016 CD cord-006870-f5w6fw6q 3702 21 . . . cord-006870-f5w6fw6q 3703 1 Delirium delirium NN cord-006870-f5w6fw6q 3703 2 was be VBD cord-006870-f5w6fw6q 3703 3 diagnosed diagnose VBN cord-006870-f5w6fw6q 3703 4 using use VBG cord-006870-f5w6fw6q 3703 5 CAM CAM NNP cord-006870-f5w6fw6q 3703 6 - - HYPH cord-006870-f5w6fw6q 3703 7 ICU ICU NNP cord-006870-f5w6fw6q 3703 8 . . . cord-006870-f5w6fw6q 3704 1 A a DT cord-006870-f5w6fw6q 3704 2 bivariate bivariate JJ cord-006870-f5w6fw6q 3704 3 and and CC cord-006870-f5w6fw6q 3704 4 multivariable multivariable JJ cord-006870-f5w6fw6q 3704 5 risk risk NN cord-006870-f5w6fw6q 3704 6 were be VBD cord-006870-f5w6fw6q 3704 7 analyzed analyze VBN cord-006870-f5w6fw6q 3704 8 and and CC cord-006870-f5w6fw6q 3704 9 presented present VBN cord-006870-f5w6fw6q 3704 10 as as IN cord-006870-f5w6fw6q 3704 11 odds odd NNS cord-006870-f5w6fw6q 3704 12 ratio ratio NN cord-006870-f5w6fw6q 3704 13 ( ( -LRB- cord-006870-f5w6fw6q 3704 14 OR OR NNP cord-006870-f5w6fw6q 3704 15 ) ) -RRB- cord-006870-f5w6fw6q 3704 16 and and CC cord-006870-f5w6fw6q 3704 17 95 95 CD cord-006870-f5w6fw6q 3704 18 % % NN cord-006870-f5w6fw6q 3704 19 confidence confidence NN cord-006870-f5w6fw6q 3704 20 interval interval NN cord-006870-f5w6fw6q 3704 21 ( ( -LRB- cord-006870-f5w6fw6q 3704 22 CI CI NNP cord-006870-f5w6fw6q 3704 23 ) ) -RRB- cord-006870-f5w6fw6q 3704 24 . . . cord-006870-f5w6fw6q 3705 1 A a DT cord-006870-f5w6fw6q 3705 2 total total NN cord-006870-f5w6fw6q 3705 3 of of IN cord-006870-f5w6fw6q 3705 4 1133 1133 CD cord-006870-f5w6fw6q 3705 5 patients patient NNS cord-006870-f5w6fw6q 3705 6 were be VBD cord-006870-f5w6fw6q 3705 7 enroll enroll PRP cord-006870-f5w6fw6q 3705 8 . . . cord-006870-f5w6fw6q 3706 1 Delirium delirium NN cord-006870-f5w6fw6q 3706 2 developed develop VBD cord-006870-f5w6fw6q 3706 3 in in IN cord-006870-f5w6fw6q 3706 4 276 276 CD cord-006870-f5w6fw6q 3706 5 patients patient NNS cord-006870-f5w6fw6q 3706 6 . . . cord-006870-f5w6fw6q 3707 1 The the DT cord-006870-f5w6fw6q 3707 2 incidence incidence NN cord-006870-f5w6fw6q 3707 3 was be VBD cord-006870-f5w6fw6q 3707 4 24.3 24.3 CD cord-006870-f5w6fw6q 3707 5 % % NN cord-006870-f5w6fw6q 3707 6 . . . cord-006870-f5w6fw6q 3708 1 Three three CD cord-006870-f5w6fw6q 3708 2 independent independent JJ cord-006870-f5w6fw6q 3708 3 predictors predictor NNS cord-006870-f5w6fw6q 3708 4 for for IN cord-006870-f5w6fw6q 3708 5 delirium delirium NN cord-006870-f5w6fw6q 3708 6 were be VBD cord-006870-f5w6fw6q 3708 7 identified identify VBN cord-006870-f5w6fw6q 3708 8 , , , cord-006870-f5w6fw6q 3708 9 Sedation sedation NN cord-006870-f5w6fw6q 3708 10 ( ( -LRB- cord-006870-f5w6fw6q 3708 11 OR OR NNP cord-006870-f5w6fw6q 3708 12 6 6 CD cord-006870-f5w6fw6q 3708 13 ( ( -LRB- cord-006870-f5w6fw6q 3708 14 95 95 CD cord-006870-f5w6fw6q 3708 15 % % NN cord-006870-f5w6fw6q 3708 16 CI ci NN cord-006870-f5w6fw6q 3708 17 , , , cord-006870-f5w6fw6q 3708 18 P p NN cord-006870-f5w6fw6q 3708 19 < < XX cord-006870-f5w6fw6q 3708 20 0,001 0,001 CD cord-006870-f5w6fw6q 3708 21 ) ) -RRB- cord-006870-f5w6fw6q 3708 22 ; ; : cord-006870-f5w6fw6q 3708 23 alcohol alcohol NN cord-006870-f5w6fw6q 3708 24 dependence dependence NN cord-006870-f5w6fw6q 3708 25 ( ( -LRB- cord-006870-f5w6fw6q 3708 26 OR or NN cord-006870-f5w6fw6q 3708 27 4,4 4,4 CD cord-006870-f5w6fw6q 3708 28 ; ; : cord-006870-f5w6fw6q 3708 29 95%CI 95%ci CD cord-006870-f5w6fw6q 3708 30 , , , cord-006870-f5w6fw6q 3708 31 P p NN cord-006870-f5w6fw6q 3708 32 < < XX cord-006870-f5w6fw6q 3708 33 0,001 0,001 CD cord-006870-f5w6fw6q 3708 34 ) ) -RRB- cord-006870-f5w6fw6q 3708 35 and and CC cord-006870-f5w6fw6q 3708 36 Glasgow Glasgow NNP cord-006870-f5w6fw6q 3708 37 coma coma NN cord-006870-f5w6fw6q 3708 38 Scale scale NN cord-006870-f5w6fw6q 3709 1 < < NNP cord-006870-f5w6fw6q 3709 2 8 8 CD cord-006870-f5w6fw6q 3709 3 ( ( -LRB- cord-006870-f5w6fw6q 3709 4 OR or CC cord-006870-f5w6fw6q 3709 5 2,2 2,2 CD cord-006870-f5w6fw6q 3709 6 ; ; : cord-006870-f5w6fw6q 3709 7 95 95 CD cord-006870-f5w6fw6q 3709 8 % % NN cord-006870-f5w6fw6q 3709 9 CI ci NN cord-006870-f5w6fw6q 3709 10 , , , cord-006870-f5w6fw6q 3709 11 P p NN cord-006870-f5w6fw6q 3709 12 < < XX cord-006870-f5w6fw6q 3709 13 0,001 0,001 CD cord-006870-f5w6fw6q 3709 14 ) ) -RRB- cord-006870-f5w6fw6q 3709 15 . . . cord-006870-f5w6fw6q 3710 1 Delirious delirious JJ cord-006870-f5w6fw6q 3710 2 patients patient NNS cord-006870-f5w6fw6q 3710 3 had have VBD cord-006870-f5w6fw6q 3710 4 a a DT cord-006870-f5w6fw6q 3710 5 significantly significantly RB cord-006870-f5w6fw6q 3710 6 APACHE APACHE NNP cord-006870-f5w6fw6q 3710 7 II II NNP cord-006870-f5w6fw6q 3710 8 ( ( -LRB- cord-006870-f5w6fw6q 3710 9 15 15 CD cord-006870-f5w6fw6q 3710 10 ( ( -LRB- cord-006870-f5w6fw6q 3710 11 11 11 CD cord-006870-f5w6fw6q 3710 12 - - SYM cord-006870-f5w6fw6q 3710 13 21 21 CD cord-006870-f5w6fw6q 3710 14 ) ) -RRB- cord-006870-f5w6fw6q 3710 15 vs vs IN cord-006870-f5w6fw6q 3710 16 13 13 CD cord-006870-f5w6fw6q 3710 17 ( ( -LRB- cord-006870-f5w6fw6q 3710 18 8 8 CD cord-006870-f5w6fw6q 3710 19 - - SYM cord-006870-f5w6fw6q 3710 20 19 19 CD cord-006870-f5w6fw6q 3710 21 ) ) -RRB- cord-006870-f5w6fw6q 3710 22 , , , cord-006870-f5w6fw6q 3710 23 P p NN cord-006870-f5w6fw6q 3710 24 < < XX cord-006870-f5w6fw6q 3710 25 0.001 0.001 CD cord-006870-f5w6fw6q 3710 26 ) ) -RRB- cord-006870-f5w6fw6q 3710 27 , , , cord-006870-f5w6fw6q 3710 28 higher high JJR cord-006870-f5w6fw6q 3710 29 SOFA sofa NN cord-006870-f5w6fw6q 3710 30 , , , cord-006870-f5w6fw6q 3710 31 ( ( -LRB- cord-006870-f5w6fw6q 3710 32 6 6 CD cord-006870-f5w6fw6q 3710 33 ( ( -LRB- cord-006870-f5w6fw6q 3710 34 3 3 CD cord-006870-f5w6fw6q 3710 35 - - SYM cord-006870-f5w6fw6q 3710 36 8 8 CD cord-006870-f5w6fw6q 3710 37 ) ) -RRB- cord-006870-f5w6fw6q 3710 38 vs vs IN cord-006870-f5w6fw6q 3710 39 4 4 CD cord-006870-f5w6fw6q 3710 40 ( ( -LRB- cord-006870-f5w6fw6q 3710 41 2 2 CD cord-006870-f5w6fw6q 3710 42 - - SYM cord-006870-f5w6fw6q 3710 43 7 7 CD cord-006870-f5w6fw6q 3710 44 ) ) -RRB- cord-006870-f5w6fw6q 3710 45 , , , cord-006870-f5w6fw6q 3710 46 P p NN cord-006870-f5w6fw6q 3710 47 < < XX cord-006870-f5w6fw6q 3710 48 0.001 0.001 CD cord-006870-f5w6fw6q 3710 49 ) ) -RRB- cord-006870-f5w6fw6q 3710 50 and and CC cord-006870-f5w6fw6q 3710 51 higher high JJR cord-006870-f5w6fw6q 3710 52 SAPS SAPS NNP cord-006870-f5w6fw6q 3710 53 III III NNP cord-006870-f5w6fw6q 3710 54 ( ( -LRB- cord-006870-f5w6fw6q 3710 55 56 56 CD cord-006870-f5w6fw6q 3710 56 ( ( -LRB- cord-006870-f5w6fw6q 3710 57 48 48 CD cord-006870-f5w6fw6q 3710 58 - - SYM cord-006870-f5w6fw6q 3710 59 65 65 CD cord-006870-f5w6fw6q 3710 60 ) ) -RRB- cord-006870-f5w6fw6q 3711 1 vs vs IN cord-006870-f5w6fw6q 3711 2 50 50 CD cord-006870-f5w6fw6q 3711 3 ( ( -LRB- cord-006870-f5w6fw6q 3711 4 41 41 CD cord-006870-f5w6fw6q 3711 5 - - SYM cord-006870-f5w6fw6q 3711 6 60 60 CD cord-006870-f5w6fw6q 3711 7 ) ) -RRB- cord-006870-f5w6fw6q 3711 8 , , , cord-006870-f5w6fw6q 3711 9 P p NN cord-006870-f5w6fw6q 3711 10 < < XX cord-006870-f5w6fw6q 3711 11 0.001 0.001 CD cord-006870-f5w6fw6q 3711 12 ) ) -RRB- cord-006870-f5w6fw6q 3711 13 . . . cord-006870-f5w6fw6q 3712 1 Other other JJ cord-006870-f5w6fw6q 3712 2 risk risk NN cord-006870-f5w6fw6q 3712 3 factors factor NNS cord-006870-f5w6fw6q 3712 4 were be VBD cord-006870-f5w6fw6q 3712 5 hyperlactatemia hyperlactatemia NNP cord-006870-f5w6fw6q 3712 6 ( ( -LRB- cord-006870-f5w6fw6q 3712 7 P<0.002 P<0.002 NNP cord-006870-f5w6fw6q 3712 8 ) ) -RRB- cord-006870-f5w6fw6q 3712 9 , , , cord-006870-f5w6fw6q 3712 10 and and CC cord-006870-f5w6fw6q 3712 11 Hypotension hypotension NN cord-006870-f5w6fw6q 3712 12 ( ( -LRB- cord-006870-f5w6fw6q 3712 13 MAP<65mmHg),(P MAP<65mmHg),(P NNP cord-006870-f5w6fw6q 3712 14 < < XX cord-006870-f5w6fw6q 3712 15 0.035 0.035 CD cord-006870-f5w6fw6q 3712 16 ) ) -RRB- cord-006870-f5w6fw6q 3712 17 . . . cord-006870-f5w6fw6q 3713 1 Patients patient NNS cord-006870-f5w6fw6q 3713 2 required require VBD cord-006870-f5w6fw6q 3713 3 prolonged prolonged JJ cord-006870-f5w6fw6q 3713 4 mechanical mechanical JJ cord-006870-f5w6fw6q 3713 5 ventilation ventilation NN cord-006870-f5w6fw6q 3713 6 , , , cord-006870-f5w6fw6q 3713 7 P p NN cord-006870-f5w6fw6q 3713 8 < < XX cord-006870-f5w6fw6q 3713 9 0.001 0.001 CD cord-006870-f5w6fw6q 3713 10 ) ) -RRB- cord-006870-f5w6fw6q 3713 11 , , , cord-006870-f5w6fw6q 3713 12 and and CC cord-006870-f5w6fw6q 3713 13 prolonged prolong VBN cord-006870-f5w6fw6q 3713 14 ICU ICU NNP cord-006870-f5w6fw6q 3713 15 - - HYPH cord-006870-f5w6fw6q 3713 16 hospital hospital NN cord-006870-f5w6fw6q 3713 17 stay stay NN cord-006870-f5w6fw6q 3713 18 . . . cord-006870-f5w6fw6q 3714 1 The the DT cord-006870-f5w6fw6q 3714 2 incidence incidence NN cord-006870-f5w6fw6q 3714 3 of of IN cord-006870-f5w6fw6q 3714 4 delirium delirium NN cord-006870-f5w6fw6q 3714 5 in in IN cord-006870-f5w6fw6q 3714 6 the the DT cord-006870-f5w6fw6q 3714 7 period period NN cord-006870-f5w6fw6q 3714 8 from from IN cord-006870-f5w6fw6q 3714 9 January January NNP cord-006870-f5w6fw6q 3714 10 1 1 CD cord-006870-f5w6fw6q 3714 11 to to IN cord-006870-f5w6fw6q 3714 12 December December NNP cord-006870-f5w6fw6q 3714 13 31 31 CD cord-006870-f5w6fw6q 3714 14 , , , cord-006870-f5w6fw6q 3714 15 2016 2016 CD cord-006870-f5w6fw6q 3714 16 was be VBD cord-006870-f5w6fw6q 3714 17 24.3 24.3 CD cord-006870-f5w6fw6q 3714 18 % % NN cord-006870-f5w6fw6q 3714 19 in in IN cord-006870-f5w6fw6q 3714 20 a a DT cord-006870-f5w6fw6q 3714 21 polyvalent polyvalent JJ cord-006870-f5w6fw6q 3714 22 intensive intensive JJ cord-006870-f5w6fw6q 3714 23 care care NN cord-006870-f5w6fw6q 3714 24 unit unit NN cord-006870-f5w6fw6q 3714 25 . . . cord-006870-f5w6fw6q 3715 1 Exposure exposure NN cord-006870-f5w6fw6q 3715 2 to to IN cord-006870-f5w6fw6q 3715 3 sedative sedative JJ cord-006870-f5w6fw6q 3715 4 medications medication NNS cord-006870-f5w6fw6q 3715 5 , , , cord-006870-f5w6fw6q 3715 6 alcohol alcohol NN cord-006870-f5w6fw6q 3715 7 dependence dependence NN cord-006870-f5w6fw6q 3715 8 , , , cord-006870-f5w6fw6q 3715 9 and and CC cord-006870-f5w6fw6q 3715 10 decrease decrease VB cord-006870-f5w6fw6q 3715 11 Glasgow Glasgow NNP cord-006870-f5w6fw6q 3715 12 coma coma NN cord-006870-f5w6fw6q 3715 13 Scale scale NN cord-006870-f5w6fw6q 3715 14 minor minor JJ cord-006870-f5w6fw6q 3715 15 8 8 CD cord-006870-f5w6fw6q 3715 16 are be VBP cord-006870-f5w6fw6q 3715 17 independent independent JJ cord-006870-f5w6fw6q 3715 18 predictors predictor NNS cord-006870-f5w6fw6q 3715 19 for for IN cord-006870-f5w6fw6q 3715 20 the the DT cord-006870-f5w6fw6q 3715 21 development development NN cord-006870-f5w6fw6q 3715 22 of of IN cord-006870-f5w6fw6q 3715 23 delirium delirium NN cord-006870-f5w6fw6q 3715 24 . . . cord-006870-f5w6fw6q 3716 1 Similarly similarly RB cord-006870-f5w6fw6q 3716 2 , , , cord-006870-f5w6fw6q 3716 3 the the DT cord-006870-f5w6fw6q 3716 4 ICU ICU NNP cord-006870-f5w6fw6q 3716 5 stay stay NN cord-006870-f5w6fw6q 3716 6 was be VBD cord-006870-f5w6fw6q 3716 7 longer long JJR cord-006870-f5w6fw6q 3716 8 in in IN cord-006870-f5w6fw6q 3716 9 the the DT cord-006870-f5w6fw6q 3716 10 group group NN cord-006870-f5w6fw6q 3716 11 that that WDT cord-006870-f5w6fw6q 3716 12 developed develop VBD cord-006870-f5w6fw6q 3716 13 delirium delirium NN cord-006870-f5w6fw6q 3716 14 ; ; : cord-006870-f5w6fw6q 3716 15 however however RB cord-006870-f5w6fw6q 3716 16 , , , cord-006870-f5w6fw6q 3716 17 mortality mortality NN cord-006870-f5w6fw6q 3716 18 was be VBD cord-006870-f5w6fw6q 3716 19 not not RB cord-006870-f5w6fw6q 3716 20 affected affect VBN cord-006870-f5w6fw6q 3716 21 by by IN cord-006870-f5w6fw6q 3716 22 the the DT cord-006870-f5w6fw6q 3716 23 presence presence NN cord-006870-f5w6fw6q 3716 24 of of IN cord-006870-f5w6fw6q 3716 25 this this DT cord-006870-f5w6fw6q 3716 26 condition condition NN cord-006870-f5w6fw6q 3716 27 . . . cord-006870-f5w6fw6q 3717 1 It -PRON- PRP cord-006870-f5w6fw6q 3717 2 has have VBZ cord-006870-f5w6fw6q 3717 3 been be VBN cord-006870-f5w6fw6q 3717 4 previously previously RB cord-006870-f5w6fw6q 3717 5 reported report VBN cord-006870-f5w6fw6q 3717 6 that that IN cord-006870-f5w6fw6q 3717 7 the the DT cord-006870-f5w6fw6q 3717 8 course course NN cord-006870-f5w6fw6q 3717 9 of of IN cord-006870-f5w6fw6q 3717 10 HSV-2 HSV-2 NNPS cord-006870-f5w6fw6q 3717 11 in in IN cord-006870-f5w6fw6q 3717 12 the the DT cord-006870-f5w6fw6q 3717 13 CNS CNS NNP cord-006870-f5w6fw6q 3717 14 is be VBZ cord-006870-f5w6fw6q 3717 15 significantly significantly RB cord-006870-f5w6fw6q 3717 16 more more RBR cord-006870-f5w6fw6q 3717 17 benign benign JJ cord-006870-f5w6fw6q 3717 18 that that IN cord-006870-f5w6fw6q 3717 19 HSV-1 hsv-1 NN cord-006870-f5w6fw6q 3717 20 , , , cord-006870-f5w6fw6q 3717 21 and and CC cord-006870-f5w6fw6q 3717 22 that that IN cord-006870-f5w6fw6q 3717 23 it -PRON- PRP cord-006870-f5w6fw6q 3717 24 rarely rarely RB cord-006870-f5w6fw6q 3717 25 causes cause VBZ cord-006870-f5w6fw6q 3717 26 encephalitis encephalitis JJ cord-006870-f5w6fw6q 3717 27 or or CC cord-006870-f5w6fw6q 3717 28 significant significant JJ cord-006870-f5w6fw6q 3717 29 morbidity morbidity NN cord-006870-f5w6fw6q 3717 30 in in IN cord-006870-f5w6fw6q 3717 31 immunocompetent immunocompetent JJ cord-006870-f5w6fw6q 3717 32 adults adult NNS cord-006870-f5w6fw6q 3717 33 . . . cord-006870-f5w6fw6q 3718 1 The the DT cord-006870-f5w6fw6q 3718 2 aim aim NN cord-006870-f5w6fw6q 3718 3 of of IN cord-006870-f5w6fw6q 3718 4 our -PRON- PRP$ cord-006870-f5w6fw6q 3718 5 study study NN cord-006870-f5w6fw6q 3718 6 was be VBD cord-006870-f5w6fw6q 3718 7 to to TO cord-006870-f5w6fw6q 3718 8 investigate investigate VB cord-006870-f5w6fw6q 3718 9 the the DT cord-006870-f5w6fw6q 3718 10 claim claim NN cord-006870-f5w6fw6q 3718 11 that that IN cord-006870-f5w6fw6q 3718 12 HSV-2 hsv-2 JJ cord-006870-f5w6fw6q 3718 13 CNS CNS NNP cord-006870-f5w6fw6q 3718 14 infections infection NNS cord-006870-f5w6fw6q 3718 15 are be VBP cord-006870-f5w6fw6q 3718 16 typically typically RB cord-006870-f5w6fw6q 3718 17 benign benign JJ cord-006870-f5w6fw6q 3718 18 , , , cord-006870-f5w6fw6q 3718 19 and and CC cord-006870-f5w6fw6q 3718 20 to to TO cord-006870-f5w6fw6q 3718 21 assess assess VB cord-006870-f5w6fw6q 3718 22 for for IN cord-006870-f5w6fw6q 3718 23 predictors predictor NNS cord-006870-f5w6fw6q 3718 24 of of IN cord-006870-f5w6fw6q 3718 25 poor poor JJ cord-006870-f5w6fw6q 3718 26 outcome outcome NN cord-006870-f5w6fw6q 3718 27 in in IN cord-006870-f5w6fw6q 3718 28 those those DT cord-006870-f5w6fw6q 3718 29 patients patient NNS cord-006870-f5w6fw6q 3718 30 who who WP cord-006870-f5w6fw6q 3718 31 do do VBP cord-006870-f5w6fw6q 3718 32 suffer suffer VB cord-006870-f5w6fw6q 3718 33 significant significant JJ cord-006870-f5w6fw6q 3718 34 morbidity morbidity NN cord-006870-f5w6fw6q 3718 35 from from IN cord-006870-f5w6fw6q 3718 36 HSV-2 hsv-2 JJ cord-006870-f5w6fw6q 3718 37 CNS CNS NNP cord-006870-f5w6fw6q 3718 38 infections infection NNS cord-006870-f5w6fw6q 3718 39 . . . cord-006870-f5w6fw6q 3719 1 Restrospective restrospective JJ cord-006870-f5w6fw6q 3719 2 chart chart NN cord-006870-f5w6fw6q 3719 3 reviews review NNS cord-006870-f5w6fw6q 3719 4 were be VBD cord-006870-f5w6fw6q 3719 5 completed complete VBN cord-006870-f5w6fw6q 3719 6 on on IN cord-006870-f5w6fw6q 3719 7 patients patient NNS cord-006870-f5w6fw6q 3719 8 with with IN cord-006870-f5w6fw6q 3719 9 a a DT cord-006870-f5w6fw6q 3719 10 positive positive JJ cord-006870-f5w6fw6q 3719 11 HSV HSV NNP cord-006870-f5w6fw6q 3719 12 PCR PCR NNP cord-006870-f5w6fw6q 3719 13 at at IN cord-006870-f5w6fw6q 3719 14 our -PRON- PRP$ cord-006870-f5w6fw6q 3719 15 institution institution NN cord-006870-f5w6fw6q 3719 16 from from IN cord-006870-f5w6fw6q 3719 17 July July NNP cord-006870-f5w6fw6q 3719 18 2008 2008 CD cord-006870-f5w6fw6q 3719 19 until until IN cord-006870-f5w6fw6q 3719 20 July July NNP cord-006870-f5w6fw6q 3719 21 2016 2016 CD cord-006870-f5w6fw6q 3719 22 . . . cord-006870-f5w6fw6q 3720 1 Patients patient NNS cord-006870-f5w6fw6q 3720 2 with with IN cord-006870-f5w6fw6q 3720 3 a a DT cord-006870-f5w6fw6q 3720 4 HSV HSV NNP cord-006870-f5w6fw6q 3720 5 PCR PCR NNP cord-006870-f5w6fw6q 3720 6 positive positive JJ cord-006870-f5w6fw6q 3720 7 for for IN cord-006870-f5w6fw6q 3720 8 HSV-2 HSV-2 NNPS cord-006870-f5w6fw6q 3720 9 were be VBD cord-006870-f5w6fw6q 3720 10 selected select VBN cord-006870-f5w6fw6q 3720 11 in in IN cord-006870-f5w6fw6q 3720 12 our -PRON- PRP$ cord-006870-f5w6fw6q 3720 13 analysis analysis NN cord-006870-f5w6fw6q 3720 14 . . . cord-006870-f5w6fw6q 3721 1 Multiple multiple JJ cord-006870-f5w6fw6q 3721 2 clinical clinical JJ cord-006870-f5w6fw6q 3721 3 variables variable NNS cord-006870-f5w6fw6q 3721 4 were be VBD cord-006870-f5w6fw6q 3721 5 evaluated evaluate VBN cord-006870-f5w6fw6q 3721 6 in in IN cord-006870-f5w6fw6q 3721 7 these these DT cord-006870-f5w6fw6q 3721 8 patients patient NNS cord-006870-f5w6fw6q 3721 9 and and CC cord-006870-f5w6fw6q 3721 10 we -PRON- PRP cord-006870-f5w6fw6q 3721 11 assessed assess VBD cord-006870-f5w6fw6q 3721 12 outcome outcome NN cord-006870-f5w6fw6q 3721 13 in in IN cord-006870-f5w6fw6q 3721 14 the the DT cord-006870-f5w6fw6q 3721 15 patient patient JJ cord-006870-f5w6fw6q 3721 16 population population NN cord-006870-f5w6fw6q 3721 17 , , , cord-006870-f5w6fw6q 3721 18 dichotomizing dichotomize VBG cord-006870-f5w6fw6q 3721 19 outcome outcome NN cord-006870-f5w6fw6q 3721 20 into into IN cord-006870-f5w6fw6q 3721 21 two two CD cord-006870-f5w6fw6q 3721 22 categories category NNS cord-006870-f5w6fw6q 3721 23 at at IN cord-006870-f5w6fw6q 3721 24 the the DT cord-006870-f5w6fw6q 3721 25 time time NN cord-006870-f5w6fw6q 3721 26 of of IN cord-006870-f5w6fw6q 3721 27 discharge discharge NN cord-006870-f5w6fw6q 3721 28 : : : cord-006870-f5w6fw6q 3721 29 good good JJ cord-006870-f5w6fw6q 3721 30 outcome outcome NN cord-006870-f5w6fw6q 3721 31 defined define VBN cord-006870-f5w6fw6q 3721 32 as as IN cord-006870-f5w6fw6q 3721 33 home home NN cord-006870-f5w6fw6q 3721 34 or or CC cord-006870-f5w6fw6q 3721 35 inpatient inpatient JJ cord-006870-f5w6fw6q 3721 36 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 3721 37 versus versus IN cord-006870-f5w6fw6q 3721 38 those those DT cord-006870-f5w6fw6q 3721 39 with with IN cord-006870-f5w6fw6q 3721 40 poor poor JJ cord-006870-f5w6fw6q 3721 41 outcome outcome NN cord-006870-f5w6fw6q 3721 42 defined define VBN cord-006870-f5w6fw6q 3721 43 as as IN cord-006870-f5w6fw6q 3721 44 death death NN cord-006870-f5w6fw6q 3721 45 , , , cord-006870-f5w6fw6q 3721 46 hospice hospice NN cord-006870-f5w6fw6q 3721 47 , , , cord-006870-f5w6fw6q 3721 48 or or CC cord-006870-f5w6fw6q 3721 49 placement placement NN cord-006870-f5w6fw6q 3721 50 in in IN cord-006870-f5w6fw6q 3721 51 a a DT cord-006870-f5w6fw6q 3721 52 long long JJ cord-006870-f5w6fw6q 3721 53 term term NN cord-006870-f5w6fw6q 3721 54 acute acute JJ cord-006870-f5w6fw6q 3721 55 care care NN cord-006870-f5w6fw6q 3721 56 facility facility NN cord-006870-f5w6fw6q 3721 57 . . . cord-006870-f5w6fw6q 3722 1 21 21 CD cord-006870-f5w6fw6q 3722 2 patients patient NNS cord-006870-f5w6fw6q 3722 3 with with IN cord-006870-f5w6fw6q 3722 4 HSV-2 hsv-2 JJ cord-006870-f5w6fw6q 3722 5 positive positive JJ cord-006870-f5w6fw6q 3722 6 PCRs pcr NNS cord-006870-f5w6fw6q 3722 7 were be VBD cord-006870-f5w6fw6q 3722 8 identified identify VBN cord-006870-f5w6fw6q 3722 9 . . . cord-006870-f5w6fw6q 3723 1 Their -PRON- PRP$ cord-006870-f5w6fw6q 3723 2 charts chart NNS cord-006870-f5w6fw6q 3723 3 were be VBD cord-006870-f5w6fw6q 3723 4 evaluated evaluate VBN cord-006870-f5w6fw6q 3723 5 for for IN cord-006870-f5w6fw6q 3723 6 demographics demographic NNS cord-006870-f5w6fw6q 3723 7 , , , cord-006870-f5w6fw6q 3723 8 laboratory laboratory NN cord-006870-f5w6fw6q 3723 9 values value NNS cord-006870-f5w6fw6q 3723 10 ( ( -LRB- cord-006870-f5w6fw6q 3723 11 serum serum NN cord-006870-f5w6fw6q 3723 12 and and CC cord-006870-f5w6fw6q 3723 13 CSF CSF NNP cord-006870-f5w6fw6q 3723 14 ) ) -RRB- cord-006870-f5w6fw6q 3723 15 , , , cord-006870-f5w6fw6q 3723 16 imaging imaging NN cord-006870-f5w6fw6q 3723 17 results result NNS cord-006870-f5w6fw6q 3723 18 , , , cord-006870-f5w6fw6q 3723 19 and and CC cord-006870-f5w6fw6q 3723 20 outcome outcome NN cord-006870-f5w6fw6q 3723 21 . . . cord-006870-f5w6fw6q 3724 1 There there EX cord-006870-f5w6fw6q 3724 2 were be VBD cord-006870-f5w6fw6q 3724 3 3 3 CD cord-006870-f5w6fw6q 3724 4 patients patient NNS cord-006870-f5w6fw6q 3724 5 with with IN cord-006870-f5w6fw6q 3724 6 poor poor JJ cord-006870-f5w6fw6q 3724 7 outcomes outcome NNS cord-006870-f5w6fw6q 3724 8 . . . cord-006870-f5w6fw6q 3725 1 It -PRON- PRP cord-006870-f5w6fw6q 3725 2 was be VBD cord-006870-f5w6fw6q 3725 3 noted note VBN cord-006870-f5w6fw6q 3725 4 that that IN cord-006870-f5w6fw6q 3725 5 they -PRON- PRP cord-006870-f5w6fw6q 3725 6 were be VBD cord-006870-f5w6fw6q 3725 7 all all RB cord-006870-f5w6fw6q 3725 8 female female JJ cord-006870-f5w6fw6q 3725 9 , , , cord-006870-f5w6fw6q 3725 10 their -PRON- PRP$ cord-006870-f5w6fw6q 3725 11 mean mean JJ cord-006870-f5w6fw6q 3725 12 age age NN cord-006870-f5w6fw6q 3725 13 was be VBD cord-006870-f5w6fw6q 3725 14 59.6 59.6 CD cord-006870-f5w6fw6q 3725 15 ( ( -LRB- cord-006870-f5w6fw6q 3725 16 vs vs IN cord-006870-f5w6fw6q 3725 17 47.2 47.2 CD cord-006870-f5w6fw6q 3725 18 in in IN cord-006870-f5w6fw6q 3725 19 the the DT cord-006870-f5w6fw6q 3725 20 good good JJ cord-006870-f5w6fw6q 3725 21 outcome outcome NN cord-006870-f5w6fw6q 3725 22 group group NN cord-006870-f5w6fw6q 3725 23 ) ) -RRB- cord-006870-f5w6fw6q 3725 24 and and CC cord-006870-f5w6fw6q 3725 25 two two CD cord-006870-f5w6fw6q 3725 26 of of IN cord-006870-f5w6fw6q 3725 27 the the DT cord-006870-f5w6fw6q 3725 28 three three CD cord-006870-f5w6fw6q 3725 29 were be VBD cord-006870-f5w6fw6q 3725 30 immunocompromised immunocompromised JJ cord-006870-f5w6fw6q 3725 31 ( ( -LRB- cord-006870-f5w6fw6q 3725 32 67 67 CD cord-006870-f5w6fw6q 3725 33 % % NN cord-006870-f5w6fw6q 3725 34 vs vs IN cord-006870-f5w6fw6q 3725 35 44 44 CD cord-006870-f5w6fw6q 3725 36 % % NN cord-006870-f5w6fw6q 3725 37 in in IN cord-006870-f5w6fw6q 3725 38 the the DT cord-006870-f5w6fw6q 3725 39 good good JJ cord-006870-f5w6fw6q 3725 40 outcome outcome NN cord-006870-f5w6fw6q 3725 41 group group NN cord-006870-f5w6fw6q 3725 42 ) ) -RRB- cord-006870-f5w6fw6q 3725 43 . . . cord-006870-f5w6fw6q 3726 1 Statistical statistical JJ cord-006870-f5w6fw6q 3726 2 analysis analysis NN cord-006870-f5w6fw6q 3726 3 was be VBD cord-006870-f5w6fw6q 3726 4 performed perform VBN cord-006870-f5w6fw6q 3726 5 however however RB cord-006870-f5w6fw6q 3726 6 due due IN cord-006870-f5w6fw6q 3726 7 to to IN cord-006870-f5w6fw6q 3726 8 the the DT cord-006870-f5w6fw6q 3726 9 small small JJ cord-006870-f5w6fw6q 3726 10 sample sample NN cord-006870-f5w6fw6q 3726 11 size size NN cord-006870-f5w6fw6q 3726 12 no no DT cord-006870-f5w6fw6q 3726 13 statistical statistical JJ cord-006870-f5w6fw6q 3726 14 significance significance NN cord-006870-f5w6fw6q 3726 15 was be VBD cord-006870-f5w6fw6q 3726 16 found find VBN cord-006870-f5w6fw6q 3726 17 . . . cord-006870-f5w6fw6q 3727 1 However however RB cord-006870-f5w6fw6q 3727 2 , , , cord-006870-f5w6fw6q 3727 3 age age NN cord-006870-f5w6fw6q 3727 4 , , , cord-006870-f5w6fw6q 3727 5 sex sex NN cord-006870-f5w6fw6q 3727 6 , , , cord-006870-f5w6fw6q 3727 7 clinical clinical JJ cord-006870-f5w6fw6q 3727 8 presentation presentation NN cord-006870-f5w6fw6q 3727 9 consistent consistent JJ cord-006870-f5w6fw6q 3727 10 with with IN cord-006870-f5w6fw6q 3727 11 encephalitis encephalitis JJ cord-006870-f5w6fw6q 3727 12 and and CC cord-006870-f5w6fw6q 3727 13 immune immune JJ cord-006870-f5w6fw6q 3727 14 status status NN cord-006870-f5w6fw6q 3727 15 seemed seem VBD cord-006870-f5w6fw6q 3727 16 to to TO cord-006870-f5w6fw6q 3727 17 have have VB cord-006870-f5w6fw6q 3727 18 a a DT cord-006870-f5w6fw6q 3727 19 trend trend NN cord-006870-f5w6fw6q 3727 20 towards towards IN cord-006870-f5w6fw6q 3727 21 poor poor JJ cord-006870-f5w6fw6q 3727 22 outcome outcome NN cord-006870-f5w6fw6q 3727 23 in in IN cord-006870-f5w6fw6q 3727 24 this this DT cord-006870-f5w6fw6q 3727 25 pilot pilot NN cord-006870-f5w6fw6q 3727 26 study study NN cord-006870-f5w6fw6q 3727 27 . . . cord-006870-f5w6fw6q 3728 1 Future future JJ cord-006870-f5w6fw6q 3728 2 study study NN cord-006870-f5w6fw6q 3728 3 with with IN cord-006870-f5w6fw6q 3728 4 larger large JJR cord-006870-f5w6fw6q 3728 5 sample sample NN cord-006870-f5w6fw6q 3728 6 size size NN cord-006870-f5w6fw6q 3728 7 is be VBZ cord-006870-f5w6fw6q 3728 8 warrented warrente VBN cord-006870-f5w6fw6q 3728 9 to to TO cord-006870-f5w6fw6q 3728 10 further further RB cord-006870-f5w6fw6q 3728 11 assess assess VB cord-006870-f5w6fw6q 3728 12 this this DT cord-006870-f5w6fw6q 3728 13 trend trend NN cord-006870-f5w6fw6q 3728 14 , , , cord-006870-f5w6fw6q 3728 15 as as IN cord-006870-f5w6fw6q 3728 16 HSV-2 HSV-2 NNP cord-006870-f5w6fw6q 3728 17 may may MD cord-006870-f5w6fw6q 3728 18 not not RB cord-006870-f5w6fw6q 3728 19 be be VB cord-006870-f5w6fw6q 3728 20 as as RB cord-006870-f5w6fw6q 3728 21 benign benign JJ cord-006870-f5w6fw6q 3728 22 as as IN cord-006870-f5w6fw6q 3728 23 previously previously RB cord-006870-f5w6fw6q 3728 24 reported report VBN cord-006870-f5w6fw6q 3728 25 . . . cord-006870-f5w6fw6q 3729 1 There there EX cord-006870-f5w6fw6q 3729 2 is be VBZ cord-006870-f5w6fw6q 3729 3 a a DT cord-006870-f5w6fw6q 3729 4 high high JJ cord-006870-f5w6fw6q 3729 5 prevalence prevalence NN cord-006870-f5w6fw6q 3729 6 of of IN cord-006870-f5w6fw6q 3729 7 non non JJ cord-006870-f5w6fw6q 3729 8 - - JJ cord-006870-f5w6fw6q 3729 9 traumatic traumatic JJ cord-006870-f5w6fw6q 3729 10 illness illness NN cord-006870-f5w6fw6q 3729 11 in in IN cord-006870-f5w6fw6q 3729 12 patients patient NNS cord-006870-f5w6fw6q 3729 13 presenting present VBG cord-006870-f5w6fw6q 3729 14 to to IN cord-006870-f5w6fw6q 3729 15 emergency emergency NN cord-006870-f5w6fw6q 3729 16 departments department NNS cord-006870-f5w6fw6q 3729 17 as as IN cord-006870-f5w6fw6q 3729 18 trauma trauma NN cord-006870-f5w6fw6q 3729 19 team team NN cord-006870-f5w6fw6q 3729 20 activations activation NNS cord-006870-f5w6fw6q 3729 21 ( ( -LRB- cord-006870-f5w6fw6q 3729 22 TTA TTA NNP cord-006870-f5w6fw6q 3729 23 ) ) -RRB- cord-006870-f5w6fw6q 3729 24 . . . cord-006870-f5w6fw6q 3730 1 We -PRON- PRP cord-006870-f5w6fw6q 3730 2 sought seek VBD cord-006870-f5w6fw6q 3730 3 to to TO cord-006870-f5w6fw6q 3730 4 determine determine VB cord-006870-f5w6fw6q 3730 5 the the DT cord-006870-f5w6fw6q 3730 6 prevalence prevalence NN cord-006870-f5w6fw6q 3730 7 of of IN cord-006870-f5w6fw6q 3730 8 neurologic neurologic JJ cord-006870-f5w6fw6q 3730 9 emergencies emergency NNS cord-006870-f5w6fw6q 3730 10 within within IN cord-006870-f5w6fw6q 3730 11 a a DT cord-006870-f5w6fw6q 3730 12 population population NN cord-006870-f5w6fw6q 3730 13 of of IN cord-006870-f5w6fw6q 3730 14 patients patient NNS cord-006870-f5w6fw6q 3730 15 receiving receive VBG cord-006870-f5w6fw6q 3730 16 a a DT cord-006870-f5w6fw6q 3730 17 TTA TTA NNP cord-006870-f5w6fw6q 3730 18 . . . cord-006870-f5w6fw6q 3731 1 This this DT cord-006870-f5w6fw6q 3731 2 was be VBD cord-006870-f5w6fw6q 3731 3 a a DT cord-006870-f5w6fw6q 3731 4 retrospective retrospective JJ cord-006870-f5w6fw6q 3731 5 review review NN cord-006870-f5w6fw6q 3731 6 of of IN cord-006870-f5w6fw6q 3731 7 prospectively prospectively RB cord-006870-f5w6fw6q 3731 8 - - HYPH cord-006870-f5w6fw6q 3731 9 collected collect VBN cord-006870-f5w6fw6q 3731 10 registry registry NN cord-006870-f5w6fw6q 3731 11 data datum NNS cord-006870-f5w6fw6q 3731 12 capturing capture VBG cord-006870-f5w6fw6q 3731 13 all all DT cord-006870-f5w6fw6q 3731 14 TTAs tta NNS cord-006870-f5w6fw6q 3731 15 in in IN cord-006870-f5w6fw6q 3731 16 a a DT cord-006870-f5w6fw6q 3731 17 highvolume highvolume NN cord-006870-f5w6fw6q 3731 18 , , , cord-006870-f5w6fw6q 3731 19 urban urban JJ cord-006870-f5w6fw6q 3731 20 , , , cord-006870-f5w6fw6q 3731 21 academic academic JJ cord-006870-f5w6fw6q 3731 22 level level NN cord-006870-f5w6fw6q 3731 23 I -PRON- PRP cord-006870-f5w6fw6q 3731 24 trauma trauma NN cord-006870-f5w6fw6q 3731 25 center center NN cord-006870-f5w6fw6q 3731 26 . . . cord-006870-f5w6fw6q 3732 1 Records record NNS cord-006870-f5w6fw6q 3732 2 from from IN cord-006870-f5w6fw6q 3732 3 June June NNP cord-006870-f5w6fw6q 3732 4 2011 2011 CD cord-006870-f5w6fw6q 3732 5 through through IN cord-006870-f5w6fw6q 3732 6 June June NNP cord-006870-f5w6fw6q 3732 7 2016 2016 CD cord-006870-f5w6fw6q 3732 8 were be VBD cord-006870-f5w6fw6q 3732 9 reviewed review VBN cord-006870-f5w6fw6q 3732 10 to to TO cord-006870-f5w6fw6q 3732 11 identify identify VB cord-006870-f5w6fw6q 3732 12 patients patient NNS cord-006870-f5w6fw6q 3732 13 found find VBN cord-006870-f5w6fw6q 3732 14 to to TO cord-006870-f5w6fw6q 3732 15 have have VB cord-006870-f5w6fw6q 3732 16 a a DT cord-006870-f5w6fw6q 3732 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 3732 18 of of IN cord-006870-f5w6fw6q 3732 19 ischemic ischemic JJ cord-006870-f5w6fw6q 3732 20 stroke stroke NN cord-006870-f5w6fw6q 3732 21 , , , cord-006870-f5w6fw6q 3732 22 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3732 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3732 24 ( ( -LRB- cord-006870-f5w6fw6q 3732 25 ICH ICH NNP cord-006870-f5w6fw6q 3732 26 ) ) -RRB- cord-006870-f5w6fw6q 3732 27 , , , cord-006870-f5w6fw6q 3732 28 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3732 29 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3732 30 ( ( -LRB- cord-006870-f5w6fw6q 3732 31 SAH SAH NNP cord-006870-f5w6fw6q 3732 32 ) ) -RRB- cord-006870-f5w6fw6q 3732 33 or or CC cord-006870-f5w6fw6q 3732 34 status status NN cord-006870-f5w6fw6q 3732 35 epilepticus epilepticus NN cord-006870-f5w6fw6q 3732 36 . . . cord-006870-f5w6fw6q 3733 1 Further further RB cord-006870-f5w6fw6q 3733 2 demographic demographic JJ cord-006870-f5w6fw6q 3733 3 , , , cord-006870-f5w6fw6q 3733 4 clinical clinical JJ cord-006870-f5w6fw6q 3733 5 , , , cord-006870-f5w6fw6q 3733 6 and and CC cord-006870-f5w6fw6q 3733 7 outcomes outcome NNS cord-006870-f5w6fw6q 3733 8 data datum NNS cord-006870-f5w6fw6q 3733 9 was be VBD cord-006870-f5w6fw6q 3733 10 then then RB cord-006870-f5w6fw6q 3733 11 abstracted abstract VBN cord-006870-f5w6fw6q 3733 12 from from IN cord-006870-f5w6fw6q 3733 13 the the DT cord-006870-f5w6fw6q 3733 14 electronic electronic JJ cord-006870-f5w6fw6q 3733 15 medical medical JJ cord-006870-f5w6fw6q 3733 16 record record NN cord-006870-f5w6fw6q 3733 17 . . . cord-006870-f5w6fw6q 3734 1 A a DT cord-006870-f5w6fw6q 3734 2 proportion proportion NN cord-006870-f5w6fw6q 3734 3 of of IN cord-006870-f5w6fw6q 3734 4 abstracted abstracted JJ cord-006870-f5w6fw6q 3734 5 charts chart NNS cord-006870-f5w6fw6q 3734 6 were be VBD cord-006870-f5w6fw6q 3734 7 reviewed review VBN cord-006870-f5w6fw6q 3734 8 by by IN cord-006870-f5w6fw6q 3734 9 an an DT cord-006870-f5w6fw6q 3734 10 independent independent JJ cord-006870-f5w6fw6q 3734 11 reviewer reviewer NN cord-006870-f5w6fw6q 3734 12 to to TO cord-006870-f5w6fw6q 3734 13 ensure ensure VB cord-006870-f5w6fw6q 3734 14 data data NN cord-006870-f5w6fw6q 3734 15 quality quality NN cord-006870-f5w6fw6q 3734 16 . . . cord-006870-f5w6fw6q 3735 1 There there EX cord-006870-f5w6fw6q 3735 2 were be VBD cord-006870-f5w6fw6q 3735 3 18,859 18,859 CD cord-006870-f5w6fw6q 3735 4 trauma trauma NN cord-006870-f5w6fw6q 3735 5 activations activation NNS cord-006870-f5w6fw6q 3735 6 in in IN cord-006870-f5w6fw6q 3735 7 the the DT cord-006870-f5w6fw6q 3735 8 registry registry NN cord-006870-f5w6fw6q 3735 9 during during IN cord-006870-f5w6fw6q 3735 10 the the DT cord-006870-f5w6fw6q 3735 11 study study NN cord-006870-f5w6fw6q 3735 12 period period NN cord-006870-f5w6fw6q 3735 13 . . . cord-006870-f5w6fw6q 3736 1 120 120 CD cord-006870-f5w6fw6q 3736 2 patients patient NNS cord-006870-f5w6fw6q 3736 3 ( ( -LRB- cord-006870-f5w6fw6q 3736 4 0.6 0.6 CD cord-006870-f5w6fw6q 3736 5 % % NN cord-006870-f5w6fw6q 3736 6 ) ) -RRB- cord-006870-f5w6fw6q 3736 7 were be VBD cord-006870-f5w6fw6q 3736 8 found find VBN cord-006870-f5w6fw6q 3736 9 to to TO cord-006870-f5w6fw6q 3736 10 have have VB cord-006870-f5w6fw6q 3736 11 a a DT cord-006870-f5w6fw6q 3736 12 nontraumatic nontraumatic JJ cord-006870-f5w6fw6q 3736 13 neurologic neurologic JJ cord-006870-f5w6fw6q 3736 14 emergency emergency NN cord-006870-f5w6fw6q 3736 15 and and CC cord-006870-f5w6fw6q 3736 16 were be VBD cord-006870-f5w6fw6q 3736 17 included include VBN cord-006870-f5w6fw6q 3736 18 in in IN cord-006870-f5w6fw6q 3736 19 the the DT cord-006870-f5w6fw6q 3736 20 analysis analysis NN cord-006870-f5w6fw6q 3736 21 . . . cord-006870-f5w6fw6q 3737 1 Of of IN cord-006870-f5w6fw6q 3737 2 these these DT cord-006870-f5w6fw6q 3737 3 patients patient NNS cord-006870-f5w6fw6q 3737 4 , , , cord-006870-f5w6fw6q 3737 5 there there EX cord-006870-f5w6fw6q 3737 6 were be VBD cord-006870-f5w6fw6q 3737 7 55 55 CD cord-006870-f5w6fw6q 3737 8 ischemic ischemic JJ cord-006870-f5w6fw6q 3737 9 stroke stroke NN cord-006870-f5w6fw6q 3737 10 ( ( -LRB- cord-006870-f5w6fw6q 3737 11 46 46 CD cord-006870-f5w6fw6q 3737 12 % % NN cord-006870-f5w6fw6q 3737 13 ) ) -RRB- cord-006870-f5w6fw6q 3737 14 , , , cord-006870-f5w6fw6q 3737 15 40 40 CD cord-006870-f5w6fw6q 3737 16 ICH ICH NNP cord-006870-f5w6fw6q 3737 17 ( ( -LRB- cord-006870-f5w6fw6q 3737 18 33 33 CD cord-006870-f5w6fw6q 3737 19 % % NN cord-006870-f5w6fw6q 3737 20 ) ) -RRB- cord-006870-f5w6fw6q 3737 21 , , , cord-006870-f5w6fw6q 3737 22 15 15 CD cord-006870-f5w6fw6q 3737 23 SAH SAH NNP cord-006870-f5w6fw6q 3737 24 ( ( -LRB- cord-006870-f5w6fw6q 3737 25 13 13 CD cord-006870-f5w6fw6q 3737 26 % % NN cord-006870-f5w6fw6q 3737 27 ) ) -RRB- cord-006870-f5w6fw6q 3737 28 , , , cord-006870-f5w6fw6q 3737 29 and and CC cord-006870-f5w6fw6q 3737 30 10 10 CD cord-006870-f5w6fw6q 3737 31 status status NN cord-006870-f5w6fw6q 3737 32 epilepticus epilepticus NN cord-006870-f5w6fw6q 3737 33 ( ( -LRB- cord-006870-f5w6fw6q 3737 34 8 8 CD cord-006870-f5w6fw6q 3737 35 % % NN cord-006870-f5w6fw6q 3737 36 ) ) -RRB- cord-006870-f5w6fw6q 3737 37 patients patient NNS cord-006870-f5w6fw6q 3737 38 . . . cord-006870-f5w6fw6q 3738 1 The the DT cord-006870-f5w6fw6q 3738 2 mean mean JJ cord-006870-f5w6fw6q 3738 3 age age NN cord-006870-f5w6fw6q 3738 4 was be VBD cord-006870-f5w6fw6q 3738 5 67 67 CD cord-006870-f5w6fw6q 3738 6 , , , cord-006870-f5w6fw6q 3738 7 and and CC cord-006870-f5w6fw6q 3738 8 70 70 CD cord-006870-f5w6fw6q 3738 9 patients patient NNS cord-006870-f5w6fw6q 3738 10 ( ( -LRB- cord-006870-f5w6fw6q 3738 11 58 58 CD cord-006870-f5w6fw6q 3738 12 % % NN cord-006870-f5w6fw6q 3738 13 ) ) -RRB- cord-006870-f5w6fw6q 3738 14 were be VBD cord-006870-f5w6fw6q 3738 15 male male JJ cord-006870-f5w6fw6q 3738 16 . . . cord-006870-f5w6fw6q 3739 1 The the DT cord-006870-f5w6fw6q 3739 2 mean mean JJ cord-006870-f5w6fw6q 3739 3 GCS GCS NNP cord-006870-f5w6fw6q 3739 4 on on IN cord-006870-f5w6fw6q 3739 5 presentation presentation NN cord-006870-f5w6fw6q 3739 6 was be VBD cord-006870-f5w6fw6q 3739 7 10 10 CD cord-006870-f5w6fw6q 3739 8 . . . cord-006870-f5w6fw6q 3740 1 About about RB cord-006870-f5w6fw6q 3740 2 half half NN cord-006870-f5w6fw6q 3740 3 of of IN cord-006870-f5w6fw6q 3740 4 these these DT cord-006870-f5w6fw6q 3740 5 patients patient NNS cord-006870-f5w6fw6q 3740 6 ( ( -LRB- cord-006870-f5w6fw6q 3740 7 43 43 CD cord-006870-f5w6fw6q 3740 8 % % NN cord-006870-f5w6fw6q 3740 9 ) ) -RRB- cord-006870-f5w6fw6q 3740 10 were be VBD cord-006870-f5w6fw6q 3740 11 intubated intubate VBN cord-006870-f5w6fw6q 3740 12 in in IN cord-006870-f5w6fw6q 3740 13 the the DT cord-006870-f5w6fw6q 3740 14 emergency emergency NN cord-006870-f5w6fw6q 3740 15 department department NN cord-006870-f5w6fw6q 3740 16 . . . cord-006870-f5w6fw6q 3741 1 All all DT cord-006870-f5w6fw6q 3741 2 patients patient NNS cord-006870-f5w6fw6q 3741 3 received receive VBD cord-006870-f5w6fw6q 3741 4 a a DT cord-006870-f5w6fw6q 3741 5 head head NN cord-006870-f5w6fw6q 3741 6 CT CT NNP cord-006870-f5w6fw6q 3741 7 scan scan NN cord-006870-f5w6fw6q 3741 8 . . . cord-006870-f5w6fw6q 3742 1 20 20 CD cord-006870-f5w6fw6q 3742 2 patients patient NNS cord-006870-f5w6fw6q 3742 3 ( ( -LRB- cord-006870-f5w6fw6q 3742 4 16 16 CD cord-006870-f5w6fw6q 3742 5 % % NN cord-006870-f5w6fw6q 3742 6 ) ) -RRB- cord-006870-f5w6fw6q 3742 7 received receive VBD cord-006870-f5w6fw6q 3742 8 intravenous intravenous JJ cord-006870-f5w6fw6q 3742 9 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 3742 10 . . . cord-006870-f5w6fw6q 3743 1 Neurologic neurologic JJ cord-006870-f5w6fw6q 3743 2 emergencies emergency NNS cord-006870-f5w6fw6q 3743 3 such such JJ cord-006870-f5w6fw6q 3743 4 as as IN cord-006870-f5w6fw6q 3743 5 ischemic ischemic JJ cord-006870-f5w6fw6q 3743 6 stroke stroke NN cord-006870-f5w6fw6q 3743 7 , , , cord-006870-f5w6fw6q 3743 8 ICH ICH NNP cord-006870-f5w6fw6q 3743 9 , , , cord-006870-f5w6fw6q 3743 10 SAH SAH NNP cord-006870-f5w6fw6q 3743 11 or or CC cord-006870-f5w6fw6q 3743 12 status status NN cord-006870-f5w6fw6q 3743 13 epilepticus epilepticus NN cord-006870-f5w6fw6q 3743 14 were be VBD cord-006870-f5w6fw6q 3743 15 common common JJ cord-006870-f5w6fw6q 3743 16 diagnoses diagnosis NNS cord-006870-f5w6fw6q 3743 17 in in IN cord-006870-f5w6fw6q 3743 18 this this DT cord-006870-f5w6fw6q 3743 19 population population NN cord-006870-f5w6fw6q 3743 20 of of IN cord-006870-f5w6fw6q 3743 21 trauma trauma NN cord-006870-f5w6fw6q 3743 22 activation activation NN cord-006870-f5w6fw6q 3743 23 patients patient NNS cord-006870-f5w6fw6q 3743 24 . . . cord-006870-f5w6fw6q 3744 1 Clinicians clinician NNS cord-006870-f5w6fw6q 3744 2 caring care VBG cord-006870-f5w6fw6q 3744 3 for for IN cord-006870-f5w6fw6q 3744 4 patients patient NNS cord-006870-f5w6fw6q 3744 5 in in IN cord-006870-f5w6fw6q 3744 6 these these DT cord-006870-f5w6fw6q 3744 7 settings setting NNS cord-006870-f5w6fw6q 3744 8 must must MD cord-006870-f5w6fw6q 3744 9 maintain maintain VB cord-006870-f5w6fw6q 3744 10 a a DT cord-006870-f5w6fw6q 3744 11 high high JJ cord-006870-f5w6fw6q 3744 12 index index NN cord-006870-f5w6fw6q 3744 13 of of IN cord-006870-f5w6fw6q 3744 14 suspicion suspicion NN cord-006870-f5w6fw6q 3744 15 for for IN cord-006870-f5w6fw6q 3744 16 non non JJ cord-006870-f5w6fw6q 3744 17 - - JJ cord-006870-f5w6fw6q 3744 18 traumatic traumatic JJ cord-006870-f5w6fw6q 3744 19 illnesses illness NNS cord-006870-f5w6fw6q 3744 20 , , , cord-006870-f5w6fw6q 3744 21 and and CC cord-006870-f5w6fw6q 3744 22 act act VB cord-006870-f5w6fw6q 3744 23 quickly quickly RB cord-006870-f5w6fw6q 3744 24 to to TO cord-006870-f5w6fw6q 3744 25 mobilize mobilize VB cord-006870-f5w6fw6q 3744 26 appropriate appropriate JJ cord-006870-f5w6fw6q 3744 27 resources resource NNS cord-006870-f5w6fw6q 3744 28 when when WRB cord-006870-f5w6fw6q 3744 29 a a DT cord-006870-f5w6fw6q 3744 30 diagnosis diagnosis NN cord-006870-f5w6fw6q 3744 31 is be VBZ cord-006870-f5w6fw6q 3744 32 made make VBN cord-006870-f5w6fw6q 3744 33 to to TO cord-006870-f5w6fw6q 3744 34 avoid avoid VB cord-006870-f5w6fw6q 3744 35 delays delay NNS cord-006870-f5w6fw6q 3744 36 in in IN cord-006870-f5w6fw6q 3744 37 care care NN cord-006870-f5w6fw6q 3744 38 . . . cord-006870-f5w6fw6q 3745 1 Further further JJ cord-006870-f5w6fw6q 3745 2 research research NN cord-006870-f5w6fw6q 3745 3 is be VBZ cord-006870-f5w6fw6q 3745 4 needed need VBN cord-006870-f5w6fw6q 3745 5 to to TO cord-006870-f5w6fw6q 3745 6 examine examine VB cord-006870-f5w6fw6q 3745 7 ways way NNS cord-006870-f5w6fw6q 3745 8 to to TO cord-006870-f5w6fw6q 3745 9 improve improve VB cord-006870-f5w6fw6q 3745 10 both both DT cord-006870-f5w6fw6q 3745 11 time time NN cord-006870-f5w6fw6q 3745 12 to to IN cord-006870-f5w6fw6q 3745 13 diagnosis diagnosis NN cord-006870-f5w6fw6q 3745 14 and and CC cord-006870-f5w6fw6q 3745 15 quality quality NN cord-006870-f5w6fw6q 3745 16 of of IN cord-006870-f5w6fw6q 3745 17 care care NN cord-006870-f5w6fw6q 3745 18 in in IN cord-006870-f5w6fw6q 3745 19 this this DT cord-006870-f5w6fw6q 3745 20 patient patient JJ cord-006870-f5w6fw6q 3745 21 population population NN cord-006870-f5w6fw6q 3745 22 . . . cord-006870-f5w6fw6q 3746 1 Formalized formalize VBN cord-006870-f5w6fw6q 3746 2 communication communication NN cord-006870-f5w6fw6q 3746 3 strategies strategy NNS cord-006870-f5w6fw6q 3746 4 decrease decrease VBP cord-006870-f5w6fw6q 3746 5 post post JJ cord-006870-f5w6fw6q 3746 6 - - JJ cord-006870-f5w6fw6q 3746 7 traumatic traumatic JJ cord-006870-f5w6fw6q 3746 8 stress stress NN cord-006870-f5w6fw6q 3746 9 disorder disorder NN cord-006870-f5w6fw6q 3746 10 ( ( -LRB- cord-006870-f5w6fw6q 3746 11 PTSD PTSD NNP cord-006870-f5w6fw6q 3746 12 ) ) -RRB- cord-006870-f5w6fw6q 3746 13 symptoms symptom NNS cord-006870-f5w6fw6q 3746 14 in in IN cord-006870-f5w6fw6q 3746 15 caregivers caregiver NNS cord-006870-f5w6fw6q 3746 16 in in IN cord-006870-f5w6fw6q 3746 17 the the DT cord-006870-f5w6fw6q 3746 18 intensive intensive JJ cord-006870-f5w6fw6q 3746 19 care care NN cord-006870-f5w6fw6q 3746 20 unit unit NN cord-006870-f5w6fw6q 3746 21 ( ( -LRB- cord-006870-f5w6fw6q 3746 22 ICU ICU NNP cord-006870-f5w6fw6q 3746 23 ) ) -RRB- cord-006870-f5w6fw6q 3746 24 . . . cord-006870-f5w6fw6q 3747 1 In in IN cord-006870-f5w6fw6q 3747 2 one one CD cord-006870-f5w6fw6q 3747 3 study study NN cord-006870-f5w6fw6q 3747 4 , , , cord-006870-f5w6fw6q 3747 5 only only RB cord-006870-f5w6fw6q 3747 6 2 2 CD cord-006870-f5w6fw6q 3747 7 % % NN cord-006870-f5w6fw6q 3747 8 of of IN cord-006870-f5w6fw6q 3747 9 family family NN cord-006870-f5w6fw6q 3747 10 meetings meeting NNS cord-006870-f5w6fw6q 3747 11 met meet VBD cord-006870-f5w6fw6q 3747 12 all all DT cord-006870-f5w6fw6q 3747 13 shared share VBN cord-006870-f5w6fw6q 3747 14 decision decision NN cord-006870-f5w6fw6q 3747 15 - - HYPH cord-006870-f5w6fw6q 3747 16 making make VBG cord-006870-f5w6fw6q 3747 17 criteria criterion NNS cord-006870-f5w6fw6q 3747 18 . . . cord-006870-f5w6fw6q 3748 1 However however RB cord-006870-f5w6fw6q 3748 2 , , , cord-006870-f5w6fw6q 3748 3 much much JJ cord-006870-f5w6fw6q 3748 4 of of IN cord-006870-f5w6fw6q 3748 5 the the DT cord-006870-f5w6fw6q 3748 6 research research NN cord-006870-f5w6fw6q 3748 7 has have VBZ cord-006870-f5w6fw6q 3748 8 focused focus VBN cord-006870-f5w6fw6q 3748 9 on on IN cord-006870-f5w6fw6q 3748 10 family family NN cord-006870-f5w6fw6q 3748 11 meetings meeting NNS cord-006870-f5w6fw6q 3748 12 , , , cord-006870-f5w6fw6q 3748 13 ignoring ignore VBG cord-006870-f5w6fw6q 3748 14 less less RBR cord-006870-f5w6fw6q 3748 15 formalized formalize VBN cord-006870-f5w6fw6q 3748 16 communication communication NN cord-006870-f5w6fw6q 3748 17 . . . cord-006870-f5w6fw6q 3749 1 The the DT cord-006870-f5w6fw6q 3749 2 decision decision NN cord-006870-f5w6fw6q 3749 3 maker maker NN cord-006870-f5w6fw6q 3749 4 ( ( -LRB- cord-006870-f5w6fw6q 3749 5 patient patient JJ cord-006870-f5w6fw6q 3749 6 or or CC cord-006870-f5w6fw6q 3749 7 caregiver caregiver NN cord-006870-f5w6fw6q 3749 8 ) ) -RRB- cord-006870-f5w6fw6q 3749 9 was be VBD cord-006870-f5w6fw6q 3749 10 interviewed interview VBN cord-006870-f5w6fw6q 3749 11 for for IN cord-006870-f5w6fw6q 3749 12 all all DT cord-006870-f5w6fw6q 3749 13 patients patient NNS cord-006870-f5w6fw6q 3749 14 admitted admit VBN cord-006870-f5w6fw6q 3749 15 to to IN cord-006870-f5w6fw6q 3749 16 the the DT cord-006870-f5w6fw6q 3749 17 medical medical JJ cord-006870-f5w6fw6q 3749 18 ( ( -LRB- cord-006870-f5w6fw6q 3749 19 MICU MICU NNP cord-006870-f5w6fw6q 3749 20 ) ) -RRB- cord-006870-f5w6fw6q 3749 21 , , , cord-006870-f5w6fw6q 3749 22 neurosciences neurosciences NNP cord-006870-f5w6fw6q 3749 23 ( ( -LRB- cord-006870-f5w6fw6q 3749 24 NSICU NSICU NNP cord-006870-f5w6fw6q 3749 25 ) ) -RRB- cord-006870-f5w6fw6q 3749 26 , , , cord-006870-f5w6fw6q 3749 27 surgical surgical JJ cord-006870-f5w6fw6q 3749 28 ( ( -LRB- cord-006870-f5w6fw6q 3749 29 SICU SICU NNP cord-006870-f5w6fw6q 3749 30 ) ) -RRB- cord-006870-f5w6fw6q 3749 31 , , , cord-006870-f5w6fw6q 3749 32 and and CC cord-006870-f5w6fw6q 3749 33 cardiothoracic cardiothoracic NN cord-006870-f5w6fw6q 3749 34 ICU ICU NNP cord-006870-f5w6fw6q 3749 35 ( ( -LRB- cord-006870-f5w6fw6q 3749 36 CTICU CTICU NNP cord-006870-f5w6fw6q 3749 37 ) ) -RRB- cord-006870-f5w6fw6q 3749 38 for for IN cord-006870-f5w6fw6q 3749 39 greater great JJR cord-006870-f5w6fw6q 3749 40 than than IN cord-006870-f5w6fw6q 3749 41 72 72 CD cord-006870-f5w6fw6q 3749 42 hours hour NNS cord-006870-f5w6fw6q 3749 43 . . . cord-006870-f5w6fw6q 3750 1 Subjects subject NNS cord-006870-f5w6fw6q 3750 2 who who WP cord-006870-f5w6fw6q 3750 3 stated state VBD cord-006870-f5w6fw6q 3750 4 significant significant JJ cord-006870-f5w6fw6q 3750 5 decisions decision NNS cord-006870-f5w6fw6q 3750 6 had have VBD cord-006870-f5w6fw6q 3750 7 been be VBN cord-006870-f5w6fw6q 3750 8 made make VBN cord-006870-f5w6fw6q 3750 9 were be VBD cord-006870-f5w6fw6q 3750 10 asked ask VBN cord-006870-f5w6fw6q 3750 11 to to TO cord-006870-f5w6fw6q 3750 12 report report VB cord-006870-f5w6fw6q 3750 13 on on IN cord-006870-f5w6fw6q 3750 14 10 10 CD cord-006870-f5w6fw6q 3750 15 aspects aspect NNS cord-006870-f5w6fw6q 3750 16 of of IN cord-006870-f5w6fw6q 3750 17 shared share VBN cord-006870-f5w6fw6q 3750 18 decision decision NN cord-006870-f5w6fw6q 3750 19 making make VBG cord-006870-f5w6fw6q 3750 20 on on IN cord-006870-f5w6fw6q 3750 21 a a DT cord-006870-f5w6fw6q 3750 22 5-point 5-point CD cord-006870-f5w6fw6q 3750 23 scale scale NN cord-006870-f5w6fw6q 3750 24 . . . cord-006870-f5w6fw6q 3751 1 They -PRON- PRP cord-006870-f5w6fw6q 3751 2 identified identify VBD cord-006870-f5w6fw6q 3751 3 the the DT cord-006870-f5w6fw6q 3751 4 lead lead NN cord-006870-f5w6fw6q 3751 5 provider provider NN cord-006870-f5w6fw6q 3751 6 , , , cord-006870-f5w6fw6q 3751 7 who who WP cord-006870-f5w6fw6q 3751 8 was be VBD cord-006870-f5w6fw6q 3751 9 subsequently subsequently RB cord-006870-f5w6fw6q 3751 10 approached approach VBN cord-006870-f5w6fw6q 3751 11 to to TO cord-006870-f5w6fw6q 3751 12 complete complete VB cord-006870-f5w6fw6q 3751 13 the the DT cord-006870-f5w6fw6q 3751 14 same same JJ cord-006870-f5w6fw6q 3751 15 questionnaire questionnaire NN cord-006870-f5w6fw6q 3751 16 . . . cord-006870-f5w6fw6q 3752 1 Overall overall RB cord-006870-f5w6fw6q 3752 2 , , , cord-006870-f5w6fw6q 3752 3 121 121 CD cord-006870-f5w6fw6q 3752 4 eligible eligible JJ cord-006870-f5w6fw6q 3752 5 decision decision NN cord-006870-f5w6fw6q 3752 6 makers maker NNS cord-006870-f5w6fw6q 3752 7 were be VBD cord-006870-f5w6fw6q 3752 8 identified identify VBN cord-006870-f5w6fw6q 3752 9 , , , cord-006870-f5w6fw6q 3752 10 47 47 CD cord-006870-f5w6fw6q 3752 11 ( ( -LRB- cord-006870-f5w6fw6q 3752 12 39 39 CD cord-006870-f5w6fw6q 3752 13 % % NN cord-006870-f5w6fw6q 3752 14 ) ) -RRB- cord-006870-f5w6fw6q 3752 15 in in IN cord-006870-f5w6fw6q 3752 16 the the DT cord-006870-f5w6fw6q 3752 17 MICU MICU NNP cord-006870-f5w6fw6q 3752 18 , , , cord-006870-f5w6fw6q 3752 19 31 31 CD cord-006870-f5w6fw6q 3752 20 ( ( -LRB- cord-006870-f5w6fw6q 3752 21 26 26 CD cord-006870-f5w6fw6q 3752 22 % % NN cord-006870-f5w6fw6q 3752 23 ) ) -RRB- cord-006870-f5w6fw6q 3752 24 in in IN cord-006870-f5w6fw6q 3752 25 the the DT cord-006870-f5w6fw6q 3752 26 NSICU NSICU NNP cord-006870-f5w6fw6q 3752 27 , , , cord-006870-f5w6fw6q 3752 28 25 25 CD cord-006870-f5w6fw6q 3752 29 ( ( -LRB- cord-006870-f5w6fw6q 3752 30 21 21 CD cord-006870-f5w6fw6q 3752 31 % % NN cord-006870-f5w6fw6q 3752 32 ) ) -RRB- cord-006870-f5w6fw6q 3752 33 in in IN cord-006870-f5w6fw6q 3752 34 the the DT cord-006870-f5w6fw6q 3752 35 SICU SICU NNP cord-006870-f5w6fw6q 3752 36 , , , cord-006870-f5w6fw6q 3752 37 and and CC cord-006870-f5w6fw6q 3752 38 18 18 CD cord-006870-f5w6fw6q 3752 39 ( ( -LRB- cord-006870-f5w6fw6q 3752 40 15 15 CD cord-006870-f5w6fw6q 3752 41 % % NN cord-006870-f5w6fw6q 3752 42 ) ) -RRB- cord-006870-f5w6fw6q 3752 43 in in IN cord-006870-f5w6fw6q 3752 44 the the DT cord-006870-f5w6fw6q 3752 45 CTICU CTICU NNP cord-006870-f5w6fw6q 3752 46 . . . cord-006870-f5w6fw6q 3753 1 Of of IN cord-006870-f5w6fw6q 3753 2 these these DT cord-006870-f5w6fw6q 3753 3 , , , cord-006870-f5w6fw6q 3753 4 63 63 CD cord-006870-f5w6fw6q 3753 5 ( ( -LRB- cord-006870-f5w6fw6q 3753 6 52 52 CD cord-006870-f5w6fw6q 3753 7 % % NN cord-006870-f5w6fw6q 3753 8 ) ) -RRB- cord-006870-f5w6fw6q 3753 9 were be VBD cord-006870-f5w6fw6q 3753 10 unable unable JJ cord-006870-f5w6fw6q 3753 11 to to TO cord-006870-f5w6fw6q 3753 12 be be VB cord-006870-f5w6fw6q 3753 13 contacted contact VBN cord-006870-f5w6fw6q 3753 14 , , , cord-006870-f5w6fw6q 3753 15 7 7 CD cord-006870-f5w6fw6q 3753 16 ( ( -LRB- cord-006870-f5w6fw6q 3753 17 6 6 CD cord-006870-f5w6fw6q 3753 18 % % NN cord-006870-f5w6fw6q 3753 19 ) ) -RRB- cord-006870-f5w6fw6q 3753 20 had have VBD cord-006870-f5w6fw6q 3753 21 insufficient insufficient JJ cord-006870-f5w6fw6q 3753 22 English English NNP cord-006870-f5w6fw6q 3753 23 , , , cord-006870-f5w6fw6q 3753 24 and and CC cord-006870-f5w6fw6q 3753 25 13 13 CD cord-006870-f5w6fw6q 3753 26 ( ( -LRB- cord-006870-f5w6fw6q 3753 27 11 11 CD cord-006870-f5w6fw6q 3753 28 % % NN cord-006870-f5w6fw6q 3753 29 ) ) -RRB- cord-006870-f5w6fw6q 3753 30 reported report VBD cord-006870-f5w6fw6q 3753 31 no no DT cord-006870-f5w6fw6q 3753 32 decisions decision NNS cord-006870-f5w6fw6q 3753 33 made make VBN cord-006870-f5w6fw6q 3753 34 , , , cord-006870-f5w6fw6q 3753 35 with with IN cord-006870-f5w6fw6q 3753 36 38 38 CD cord-006870-f5w6fw6q 3753 37 ( ( -LRB- cord-006870-f5w6fw6q 3753 38 31 31 CD cord-006870-f5w6fw6q 3753 39 % % NN cord-006870-f5w6fw6q 3753 40 ) ) -RRB- cord-006870-f5w6fw6q 3753 41 enrolled enrol VBN cord-006870-f5w6fw6q 3753 42 . . . cord-006870-f5w6fw6q 3754 1 Nineteen nineteen CD cord-006870-f5w6fw6q 3754 2 ( ( -LRB- cord-006870-f5w6fw6q 3754 3 50 50 CD cord-006870-f5w6fw6q 3754 4 % % NN cord-006870-f5w6fw6q 3754 5 ) ) -RRB- cord-006870-f5w6fw6q 3754 6 provider provider NN cord-006870-f5w6fw6q 3754 7 interviews interview NNS cord-006870-f5w6fw6q 3754 8 were be VBD cord-006870-f5w6fw6q 3754 9 completed complete VBN cord-006870-f5w6fw6q 3754 10 . . . cord-006870-f5w6fw6q 3755 1 Topics topic NNS cord-006870-f5w6fw6q 3755 2 most most RBS cord-006870-f5w6fw6q 3755 3 reported report VBD cord-006870-f5w6fw6q 3755 4 covered cover VBN cord-006870-f5w6fw6q 3755 5 " " `` cord-006870-f5w6fw6q 3755 6 Well well UH cord-006870-f5w6fw6q 3755 7 " " '' cord-006870-f5w6fw6q 3755 8 or or CC cord-006870-f5w6fw6q 3755 9 " " `` cord-006870-f5w6fw6q 3755 10 Thoroughly thoroughly RB cord-006870-f5w6fw6q 3755 11 " " '' cord-006870-f5w6fw6q 3755 12 by by IN cord-006870-f5w6fw6q 3755 13 caregivers caregiver NNS cord-006870-f5w6fw6q 3755 14 were be VBD cord-006870-f5w6fw6q 3755 15 assessment assessment NN cord-006870-f5w6fw6q 3755 16 of of IN cord-006870-f5w6fw6q 3755 17 understanding understanding NN cord-006870-f5w6fw6q 3755 18 ( ( -LRB- cord-006870-f5w6fw6q 3755 19 36 36 CD cord-006870-f5w6fw6q 3755 20 , , , cord-006870-f5w6fw6q 3755 21 95 95 CD cord-006870-f5w6fw6q 3755 22 % % NN cord-006870-f5w6fw6q 3755 23 ) ) -RRB- cord-006870-f5w6fw6q 3755 24 and and CC cord-006870-f5w6fw6q 3755 25 the the DT cord-006870-f5w6fw6q 3755 26 nature nature NN cord-006870-f5w6fw6q 3755 27 of of IN cord-006870-f5w6fw6q 3755 28 the the DT cord-006870-f5w6fw6q 3755 29 decision decision NN cord-006870-f5w6fw6q 3755 30 ( ( -LRB- cord-006870-f5w6fw6q 3755 31 35 35 CD cord-006870-f5w6fw6q 3755 32 , , , cord-006870-f5w6fw6q 3755 33 92 92 CD cord-006870-f5w6fw6q 3755 34 % % NN cord-006870-f5w6fw6q 3755 35 ) ) -RRB- cord-006870-f5w6fw6q 3755 36 , , , cord-006870-f5w6fw6q 3755 37 while while IN cord-006870-f5w6fw6q 3755 38 those those DT cord-006870-f5w6fw6q 3755 39 least least JJS cord-006870-f5w6fw6q 3755 40 covered covered JJ cord-006870-f5w6fw6q 3755 41 were be VBD cord-006870-f5w6fw6q 3755 42 need nee VBN cord-006870-f5w6fw6q 3755 43 for for IN cord-006870-f5w6fw6q 3755 44 input input NN cord-006870-f5w6fw6q 3755 45 from from IN cord-006870-f5w6fw6q 3755 46 others other NNS cord-006870-f5w6fw6q 3755 47 ( ( -LRB- cord-006870-f5w6fw6q 3755 48 23 23 CD cord-006870-f5w6fw6q 3755 49 , , , cord-006870-f5w6fw6q 3755 50 61 61 CD cord-006870-f5w6fw6q 3755 51 % % NN cord-006870-f5w6fw6q 3755 52 ) ) -RRB- cord-006870-f5w6fw6q 3755 53 and and CC cord-006870-f5w6fw6q 3755 54 the the DT cord-006870-f5w6fw6q 3755 55 context context NN cord-006870-f5w6fw6q 3755 56 of of IN cord-006870-f5w6fw6q 3755 57 the the DT cord-006870-f5w6fw6q 3755 58 decision decision NN cord-006870-f5w6fw6q 3755 59 ( ( -LRB- cord-006870-f5w6fw6q 3755 60 25 25 CD cord-006870-f5w6fw6q 3755 61 , , , cord-006870-f5w6fw6q 3755 62 66 66 CD cord-006870-f5w6fw6q 3755 63 % % NN cord-006870-f5w6fw6q 3755 64 ) ) -RRB- cord-006870-f5w6fw6q 3755 65 . . . cord-006870-f5w6fw6q 3756 1 Topics topic NNS cord-006870-f5w6fw6q 3756 2 reported report VBD cord-006870-f5w6fw6q 3756 3 most most RBS cord-006870-f5w6fw6q 3756 4 covered cover VBN cord-006870-f5w6fw6q 3756 5 by by IN cord-006870-f5w6fw6q 3756 6 providers provider NNS cord-006870-f5w6fw6q 3756 7 were be VBD cord-006870-f5w6fw6q 3756 8 the the DT cord-006870-f5w6fw6q 3756 9 nature nature NN cord-006870-f5w6fw6q 3756 10 of of IN cord-006870-f5w6fw6q 3756 11 the the DT cord-006870-f5w6fw6q 3756 12 decision decision NN cord-006870-f5w6fw6q 3756 13 ( ( -LRB- cord-006870-f5w6fw6q 3756 14 18 18 CD cord-006870-f5w6fw6q 3756 15 , , , cord-006870-f5w6fw6q 3756 16 95 95 CD cord-006870-f5w6fw6q 3756 17 % % NN cord-006870-f5w6fw6q 3756 18 ) ) -RRB- cord-006870-f5w6fw6q 3756 19 and and CC cord-006870-f5w6fw6q 3756 20 opinions opinion NNS cord-006870-f5w6fw6q 3756 21 about about IN cord-006870-f5w6fw6q 3756 22 the the DT cord-006870-f5w6fw6q 3756 23 treatment treatment NN cord-006870-f5w6fw6q 3756 24 decision decision NN cord-006870-f5w6fw6q 3756 25 ( ( -LRB- cord-006870-f5w6fw6q 3756 26 17 17 CD cord-006870-f5w6fw6q 3756 27 , , , cord-006870-f5w6fw6q 3756 28 89 89 CD cord-006870-f5w6fw6q 3756 29 % % NN cord-006870-f5w6fw6q 3756 30 ) ) -RRB- cord-006870-f5w6fw6q 3756 31 , , , cord-006870-f5w6fw6q 3756 32 while while IN cord-006870-f5w6fw6q 3756 33 those those DT cord-006870-f5w6fw6q 3756 34 least least JJS cord-006870-f5w6fw6q 3756 35 covered covered JJ cord-006870-f5w6fw6q 3756 36 were be VBD cord-006870-f5w6fw6q 3756 37 patient patient JJ cord-006870-f5w6fw6q 3756 38 's 's POS cord-006870-f5w6fw6q 3756 39 values value NNS cord-006870-f5w6fw6q 3756 40 and and CC cord-006870-f5w6fw6q 3756 41 preferences preference NNS cord-006870-f5w6fw6q 3756 42 ( ( -LRB- cord-006870-f5w6fw6q 3756 43 12 12 CD cord-006870-f5w6fw6q 3756 44 , , , cord-006870-f5w6fw6q 3756 45 63 63 CD cord-006870-f5w6fw6q 3756 46 % % NN cord-006870-f5w6fw6q 3756 47 ) ) -RRB- cord-006870-f5w6fw6q 3756 48 and and CC cord-006870-f5w6fw6q 3756 49 their -PRON- PRP$ cord-006870-f5w6fw6q 3756 50 preferred preferred JJ cord-006870-f5w6fw6q 3756 51 role role NN cord-006870-f5w6fw6q 3756 52 in in IN cord-006870-f5w6fw6q 3756 53 decision decision NN cord-006870-f5w6fw6q 3756 54 making make VBG cord-006870-f5w6fw6q 3756 55 ( ( -LRB- cord-006870-f5w6fw6q 3756 56 10 10 CD cord-006870-f5w6fw6q 3756 57 , , , cord-006870-f5w6fw6q 3756 58 53 53 CD cord-006870-f5w6fw6q 3756 59 % % NN cord-006870-f5w6fw6q 3756 60 ) ) -RRB- cord-006870-f5w6fw6q 3756 61 . . . cord-006870-f5w6fw6q 3757 1 Eighteen eighteen CD cord-006870-f5w6fw6q 3757 2 ( ( -LRB- cord-006870-f5w6fw6q 3757 3 47 47 CD cord-006870-f5w6fw6q 3757 4 % % NN cord-006870-f5w6fw6q 3757 5 ) ) -RRB- cord-006870-f5w6fw6q 3757 6 caregivers caregiver NNS cord-006870-f5w6fw6q 3757 7 and and CC cord-006870-f5w6fw6q 3757 8 5 5 CD cord-006870-f5w6fw6q 3757 9 ( ( -LRB- cord-006870-f5w6fw6q 3757 10 26 26 CD cord-006870-f5w6fw6q 3757 11 % % NN cord-006870-f5w6fw6q 3757 12 ) ) -RRB- cord-006870-f5w6fw6q 3757 13 providers provider NNS cord-006870-f5w6fw6q 3757 14 described describe VBD cord-006870-f5w6fw6q 3757 15 all all DT cord-006870-f5w6fw6q 3757 16 topics topic NNS cord-006870-f5w6fw6q 3757 17 covered cover VBN cord-006870-f5w6fw6q 3757 18 " " `` cord-006870-f5w6fw6q 3757 19 Well well UH cord-006870-f5w6fw6q 3757 20 " " '' cord-006870-f5w6fw6q 3757 21 or or CC cord-006870-f5w6fw6q 3757 22 " " `` cord-006870-f5w6fw6q 3757 23 Thoroughly thoroughly RB cord-006870-f5w6fw6q 3757 24 . . . cord-006870-f5w6fw6q 3757 25 " " '' cord-006870-f5w6fw6q 3758 1 These these DT cord-006870-f5w6fw6q 3758 2 results result NNS cord-006870-f5w6fw6q 3758 3 demonstrate demonstrate VBP cord-006870-f5w6fw6q 3758 4 differences difference NNS cord-006870-f5w6fw6q 3758 5 in in IN cord-006870-f5w6fw6q 3758 6 perception perception NN cord-006870-f5w6fw6q 3758 7 of of IN cord-006870-f5w6fw6q 3758 8 shared share VBN cord-006870-f5w6fw6q 3758 9 decision decision NN cord-006870-f5w6fw6q 3758 10 making make VBG cord-006870-f5w6fw6q 3758 11 by by IN cord-006870-f5w6fw6q 3758 12 decision decision NN cord-006870-f5w6fw6q 3758 13 makers maker NNS cord-006870-f5w6fw6q 3758 14 and and CC cord-006870-f5w6fw6q 3758 15 providers provider NNS cord-006870-f5w6fw6q 3758 16 . . . cord-006870-f5w6fw6q 3759 1 Further further JJ cord-006870-f5w6fw6q 3759 2 qualitative qualitative JJ cord-006870-f5w6fw6q 3759 3 investigation investigation NN cord-006870-f5w6fw6q 3759 4 is be VBZ cord-006870-f5w6fw6q 3759 5 underway underway JJ cord-006870-f5w6fw6q 3759 6 to to TO cord-006870-f5w6fw6q 3759 7 elucidate elucidate VB cord-006870-f5w6fw6q 3759 8 the the DT cord-006870-f5w6fw6q 3759 9 nature nature NN cord-006870-f5w6fw6q 3759 10 of of IN cord-006870-f5w6fw6q 3759 11 these these DT cord-006870-f5w6fw6q 3759 12 inconsistencies inconsistency NNS cord-006870-f5w6fw6q 3759 13 . . . cord-006870-f5w6fw6q 3760 1 Organ organ NN cord-006870-f5w6fw6q 3760 2 donation donation NN cord-006870-f5w6fw6q 3760 3 is be VBZ cord-006870-f5w6fw6q 3760 4 a a DT cord-006870-f5w6fw6q 3760 5 life life NN cord-006870-f5w6fw6q 3760 6 - - HYPH cord-006870-f5w6fw6q 3760 7 saving save VBG cord-006870-f5w6fw6q 3760 8 medical medical JJ cord-006870-f5w6fw6q 3760 9 intervention intervention NN cord-006870-f5w6fw6q 3760 10 . . . cord-006870-f5w6fw6q 3761 1 The the DT cord-006870-f5w6fw6q 3761 2 effect effect NN cord-006870-f5w6fw6q 3761 3 of of IN cord-006870-f5w6fw6q 3761 4 race race NN cord-006870-f5w6fw6q 3761 5 , , , cord-006870-f5w6fw6q 3761 6 insurance insurance NN cord-006870-f5w6fw6q 3761 7 and and CC cord-006870-f5w6fw6q 3761 8 economic economic JJ cord-006870-f5w6fw6q 3761 9 status status NN cord-006870-f5w6fw6q 3761 10 on on IN cord-006870-f5w6fw6q 3761 11 organ organ NN cord-006870-f5w6fw6q 3761 12 donation donation NN cord-006870-f5w6fw6q 3761 13 and and CC cord-006870-f5w6fw6q 3761 14 recipients recipient NNS cord-006870-f5w6fw6q 3761 15 has have VBZ cord-006870-f5w6fw6q 3761 16 not not RB cord-006870-f5w6fw6q 3761 17 been be VBN cord-006870-f5w6fw6q 3761 18 studied study VBN cord-006870-f5w6fw6q 3761 19 at at IN cord-006870-f5w6fw6q 3761 20 a a DT cord-006870-f5w6fw6q 3761 21 National national JJ cord-006870-f5w6fw6q 3761 22 level level NN cord-006870-f5w6fw6q 3761 23 . . . cord-006870-f5w6fw6q 3762 1 In in IN cord-006870-f5w6fw6q 3762 2 our -PRON- PRP$ cord-006870-f5w6fw6q 3762 3 study study NN cord-006870-f5w6fw6q 3762 4 , , , cord-006870-f5w6fw6q 3762 5 we -PRON- PRP cord-006870-f5w6fw6q 3762 6 analyzed analyze VBD cord-006870-f5w6fw6q 3762 7 Nationwide Nationwide NNP cord-006870-f5w6fw6q 3762 8 in in IN cord-006870-f5w6fw6q 3762 9 - - HYPH cord-006870-f5w6fw6q 3762 10 patient patient NN cord-006870-f5w6fw6q 3762 11 ( ( -LRB- cord-006870-f5w6fw6q 3762 12 NIS NIS NNP cord-006870-f5w6fw6q 3762 13 ) ) -RRB- cord-006870-f5w6fw6q 3762 14 database database NN cord-006870-f5w6fw6q 3762 15 of of IN cord-006870-f5w6fw6q 3762 16 years year NNS cord-006870-f5w6fw6q 3762 17 2011 2011 CD cord-006870-f5w6fw6q 3762 18 - - SYM cord-006870-f5w6fw6q 3762 19 14 14 CD cord-006870-f5w6fw6q 3762 20 to to TO cord-006870-f5w6fw6q 3762 21 select select VB cord-006870-f5w6fw6q 3762 22 donors donor NNS cord-006870-f5w6fw6q 3762 23 and and CC cord-006870-f5w6fw6q 3762 24 recipients recipient NNS cord-006870-f5w6fw6q 3762 25 . . . cord-006870-f5w6fw6q 3763 1 Baseline baseline JJ cord-006870-f5w6fw6q 3763 2 demographics demographic NNS cord-006870-f5w6fw6q 3763 3 ( ( -LRB- cord-006870-f5w6fw6q 3763 4 i.e. i.e. FW cord-006870-f5w6fw6q 3763 5 , , , cord-006870-f5w6fw6q 3763 6 Age age NN cord-006870-f5w6fw6q 3763 7 , , , cord-006870-f5w6fw6q 3763 8 gender gender NN cord-006870-f5w6fw6q 3763 9 , , , cord-006870-f5w6fw6q 3763 10 race race NN cord-006870-f5w6fw6q 3763 11 ) ) -RRB- cord-006870-f5w6fw6q 3763 12 , , , cord-006870-f5w6fw6q 3763 13 insurance insurance NN cord-006870-f5w6fw6q 3763 14 status status NN cord-006870-f5w6fw6q 3763 15 and and CC cord-006870-f5w6fw6q 3763 16 socio socio JJ cord-006870-f5w6fw6q 3763 17 - - HYPH cord-006870-f5w6fw6q 3763 18 economic economic JJ cord-006870-f5w6fw6q 3763 19 status status NN cord-006870-f5w6fw6q 3763 20 was be VBD cord-006870-f5w6fw6q 3763 21 compared compare VBN cord-006870-f5w6fw6q 3763 22 between between IN cord-006870-f5w6fw6q 3763 23 two two CD cord-006870-f5w6fw6q 3763 24 groups group NNS cord-006870-f5w6fw6q 3763 25 . . . cord-006870-f5w6fw6q 3764 1 We -PRON- PRP cord-006870-f5w6fw6q 3764 2 identified identify VBD cord-006870-f5w6fw6q 3764 3 donors donor NNS cord-006870-f5w6fw6q 3764 4 ( ( -LRB- cord-006870-f5w6fw6q 3764 5 n=26821 n=26821 NNP cord-006870-f5w6fw6q 3764 6 ) ) -RRB- cord-006870-f5w6fw6q 3764 7 and and CC cord-006870-f5w6fw6q 3764 8 recipients recipient NNS cord-006870-f5w6fw6q 3764 9 ( ( -LRB- cord-006870-f5w6fw6q 3764 10 n=108953 n=108953 NNS cord-006870-f5w6fw6q 3764 11 ) ) -RRB- cord-006870-f5w6fw6q 3764 12 from from IN cord-006870-f5w6fw6q 3764 13 2011 2011 CD cord-006870-f5w6fw6q 3764 14 - - SYM cord-006870-f5w6fw6q 3764 15 14 14 CD cord-006870-f5w6fw6q 3764 16 . . . cord-006870-f5w6fw6q 3765 1 Recipients recipient NNS cord-006870-f5w6fw6q 3765 2 were be VBD cord-006870-f5w6fw6q 3765 3 significantly significantly RB cord-006870-f5w6fw6q 3765 4 older old JJR cord-006870-f5w6fw6q 3765 5 ( ( -LRB- cord-006870-f5w6fw6q 3765 6 Mean mean JJ cord-006870-f5w6fw6q 3765 7 age age NN cord-006870-f5w6fw6q 3765 8 ± ± NNP cord-006870-f5w6fw6q 3765 9 SD SD NNP cord-006870-f5w6fw6q 3765 10 , , , cord-006870-f5w6fw6q 3765 11 50.3±16.3 50.3±16.3 CD cord-006870-f5w6fw6q 3765 12 Vs Vs NNP cord-006870-f5w6fw6q 3765 13 41.5±13.5 41.5±13.5 CD cord-006870-f5w6fw6q 3765 14 , , , cord-006870-f5w6fw6q 3765 15 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 3765 16 ) ) -RRB- cord-006870-f5w6fw6q 3765 17 . . . cord-006870-f5w6fw6q 3766 1 Donors donor NNS cord-006870-f5w6fw6q 3766 2 had have VBD cord-006870-f5w6fw6q 3766 3 higher high JJR cord-006870-f5w6fw6q 3766 4 ( ( -LRB- cord-006870-f5w6fw6q 3766 5 57.1 57.1 CD cord-006870-f5w6fw6q 3766 6 % % NN cord-006870-f5w6fw6q 3766 7 vs vs IN cord-006870-f5w6fw6q 3766 8 38.3 38.3 CD cord-006870-f5w6fw6q 3766 9 % % NN cord-006870-f5w6fw6q 3766 10 , , , cord-006870-f5w6fw6q 3766 11 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 3766 12 ) ) -RRB- cord-006870-f5w6fw6q 3766 13 proportion proportion NN cord-006870-f5w6fw6q 3766 14 of of IN cord-006870-f5w6fw6q 3766 15 women woman NNS cord-006870-f5w6fw6q 3766 16 compared compare VBN cord-006870-f5w6fw6q 3766 17 to to IN cord-006870-f5w6fw6q 3766 18 recipients recipient NNS cord-006870-f5w6fw6q 3766 19 . . . cord-006870-f5w6fw6q 3767 1 Both both DT cord-006870-f5w6fw6q 3767 2 groups group NNS cord-006870-f5w6fw6q 3767 3 had have VBD cord-006870-f5w6fw6q 3767 4 a a DT cord-006870-f5w6fw6q 3767 5 higher high JJR cord-006870-f5w6fw6q 3767 6 proportion proportion NN cord-006870-f5w6fw6q 3767 7 of of IN cord-006870-f5w6fw6q 3767 8 Whites white NNS cord-006870-f5w6fw6q 3767 9 compared compare VBN cord-006870-f5w6fw6q 3767 10 to to IN cord-006870-f5w6fw6q 3767 11 other other JJ cord-006870-f5w6fw6q 3767 12 races race NNS cord-006870-f5w6fw6q 3767 13 ( ( -LRB- cord-006870-f5w6fw6q 3767 14 67 67 CD cord-006870-f5w6fw6q 3767 15 % % NN cord-006870-f5w6fw6q 3767 16 and and CC cord-006870-f5w6fw6q 3767 17 57.9 57.9 CD cord-006870-f5w6fw6q 3767 18 % % NN cord-006870-f5w6fw6q 3767 19 respectively respectively RB cord-006870-f5w6fw6q 3767 20 ) ) -RRB- cord-006870-f5w6fw6q 3767 21 . . . cord-006870-f5w6fw6q 3768 1 Insured insure VBN cord-006870-f5w6fw6q 3768 2 patients patient NNS cord-006870-f5w6fw6q 3768 3 were be VBD cord-006870-f5w6fw6q 3768 4 largely largely RB cord-006870-f5w6fw6q 3768 5 represented represent VBN cord-006870-f5w6fw6q 3768 6 in in IN cord-006870-f5w6fw6q 3768 7 both both DT cord-006870-f5w6fw6q 3768 8 groups group NNS cord-006870-f5w6fw6q 3768 9 with with IN cord-006870-f5w6fw6q 3768 10 Private private JJ cord-006870-f5w6fw6q 3768 11 insurance insurance NN cord-006870-f5w6fw6q 3768 12 predominating predominate VBG cord-006870-f5w6fw6q 3768 13 in in IN cord-006870-f5w6fw6q 3768 14 donors donor NNS cord-006870-f5w6fw6q 3768 15 ( ( -LRB- cord-006870-f5w6fw6q 3768 16 67 67 CD cord-006870-f5w6fw6q 3768 17 % % NN cord-006870-f5w6fw6q 3768 18 ) ) -RRB- cord-006870-f5w6fw6q 3768 19 and and CC cord-006870-f5w6fw6q 3768 20 Medicare Medicare NNP cord-006870-f5w6fw6q 3768 21 in in IN cord-006870-f5w6fw6q 3768 22 Recipients recipient NNS cord-006870-f5w6fw6q 3768 23 ( ( -LRB- cord-006870-f5w6fw6q 3768 24 50.2 50.2 CD cord-006870-f5w6fw6q 3768 25 % % NN cord-006870-f5w6fw6q 3768 26 ) ) -RRB- cord-006870-f5w6fw6q 3768 27 . . . cord-006870-f5w6fw6q 3769 1 Interestingly interestingly RB cord-006870-f5w6fw6q 3769 2 , , , cord-006870-f5w6fw6q 3769 3 Self Self NNP cord-006870-f5w6fw6q 3769 4 pay pay VBP cord-006870-f5w6fw6q 3769 5 represented represent VBN cord-006870-f5w6fw6q 3769 6 15.5 15.5 CD cord-006870-f5w6fw6q 3769 7 % % NN cord-006870-f5w6fw6q 3769 8 of of IN cord-006870-f5w6fw6q 3769 9 Donors donor NNS cord-006870-f5w6fw6q 3769 10 but but CC cord-006870-f5w6fw6q 3769 11 only only RB cord-006870-f5w6fw6q 3769 12 0.8 0.8 CD cord-006870-f5w6fw6q 3769 13 % % NN cord-006870-f5w6fw6q 3769 14 of of IN cord-006870-f5w6fw6q 3769 15 Recipients recipient NNS cord-006870-f5w6fw6q 3769 16 . . . cord-006870-f5w6fw6q 3770 1 Race race NN cord-006870-f5w6fw6q 3770 2 , , , cord-006870-f5w6fw6q 3770 3 insurance insurance NN cord-006870-f5w6fw6q 3770 4 and and CC cord-006870-f5w6fw6q 3770 5 socioeconomic socioeconomic JJ cord-006870-f5w6fw6q 3770 6 status status NN cord-006870-f5w6fw6q 3770 7 seem seem VBP cord-006870-f5w6fw6q 3770 8 to to TO cord-006870-f5w6fw6q 3770 9 be be VB cord-006870-f5w6fw6q 3770 10 evenly evenly RB cord-006870-f5w6fw6q 3770 11 similarly similarly RB cord-006870-f5w6fw6q 3770 12 represented represent VBN cord-006870-f5w6fw6q 3770 13 in in IN cord-006870-f5w6fw6q 3770 14 Donors donor NNS cord-006870-f5w6fw6q 3770 15 and and CC cord-006870-f5w6fw6q 3770 16 Recipients Recipients NNPS cord-006870-f5w6fw6q 3770 17 . . . cord-006870-f5w6fw6q 3771 1 Interestingly interestingly RB cord-006870-f5w6fw6q 3771 2 Self self NN cord-006870-f5w6fw6q 3771 3 pay pay VBP cord-006870-f5w6fw6q 3771 4 insurance insurance NN cord-006870-f5w6fw6q 3771 5 has have VBZ cord-006870-f5w6fw6q 3771 6 a a DT cord-006870-f5w6fw6q 3771 7 higher high JJR cord-006870-f5w6fw6q 3771 8 distribution distribution NN cord-006870-f5w6fw6q 3771 9 among among IN cord-006870-f5w6fw6q 3771 10 Donors donor NNS cord-006870-f5w6fw6q 3771 11 than than IN cord-006870-f5w6fw6q 3771 12 Recipients recipient NNS cord-006870-f5w6fw6q 3771 13 . . . cord-006870-f5w6fw6q 3772 1 Central central JJ cord-006870-f5w6fw6q 3772 2 line line NN cord-006870-f5w6fw6q 3772 3 - - HYPH cord-006870-f5w6fw6q 3772 4 associated associate VBN cord-006870-f5w6fw6q 3772 5 bloodstream bloodstream NN cord-006870-f5w6fw6q 3772 6 infections infection NNS cord-006870-f5w6fw6q 3772 7 ( ( -LRB- cord-006870-f5w6fw6q 3772 8 CLABSIs clabsi NNS cord-006870-f5w6fw6q 3772 9 ) ) -RRB- cord-006870-f5w6fw6q 3772 10 are be VBP cord-006870-f5w6fw6q 3772 11 a a DT cord-006870-f5w6fw6q 3772 12 common common JJ cord-006870-f5w6fw6q 3772 13 health health NN cord-006870-f5w6fw6q 3772 14 care care NN cord-006870-f5w6fw6q 3772 15 associated associate VBD cord-006870-f5w6fw6q 3772 16 infection infection NN cord-006870-f5w6fw6q 3772 17 accounting account VBG cord-006870-f5w6fw6q 3772 18 for for IN cord-006870-f5w6fw6q 3772 19 30,100 30,100 CD cord-006870-f5w6fw6q 3772 20 infections infection NNS cord-006870-f5w6fw6q 3772 21 annually annually RB cord-006870-f5w6fw6q 3772 22 in in IN cord-006870-f5w6fw6q 3772 23 the the DT cord-006870-f5w6fw6q 3772 24 intensive intensive JJ cord-006870-f5w6fw6q 3772 25 care care NN cord-006870-f5w6fw6q 3772 26 and and CC cord-006870-f5w6fw6q 3772 27 acute acute JJ cord-006870-f5w6fw6q 3772 28 care care NN cord-006870-f5w6fw6q 3772 29 areas area NNS cord-006870-f5w6fw6q 3772 30 ( ( -LRB- cord-006870-f5w6fw6q 3772 31 CDC,2014 CDC,2014 NNP cord-006870-f5w6fw6q 3772 32 ) ) -RRB- cord-006870-f5w6fw6q 3772 33 . . . cord-006870-f5w6fw6q 3773 1 According accord VBG cord-006870-f5w6fw6q 3773 2 to to IN cord-006870-f5w6fw6q 3773 3 the the DT cord-006870-f5w6fw6q 3773 4 Center Center NNP cord-006870-f5w6fw6q 3773 5 for for IN cord-006870-f5w6fw6q 3773 6 Disease Disease NNP cord-006870-f5w6fw6q 3773 7 Control Control NNP cord-006870-f5w6fw6q 3773 8 , , , cord-006870-f5w6fw6q 3773 9 CLABSIs CLABSIs NNP cord-006870-f5w6fw6q 3773 10 result result VBP cord-006870-f5w6fw6q 3773 11 in in IN cord-006870-f5w6fw6q 3773 12 thousands thousand NNS cord-006870-f5w6fw6q 3773 13 of of IN cord-006870-f5w6fw6q 3773 14 deaths death NNS cord-006870-f5w6fw6q 3773 15 yearly yearly JJ cord-006870-f5w6fw6q 3773 16 and and CC cord-006870-f5w6fw6q 3773 17 upwards upwards RB cord-006870-f5w6fw6q 3773 18 of of IN cord-006870-f5w6fw6q 3773 19 billions billion NNS cord-006870-f5w6fw6q 3773 20 of of IN cord-006870-f5w6fw6q 3773 21 health health NN cord-006870-f5w6fw6q 3773 22 care care NN cord-006870-f5w6fw6q 3773 23 dollars dollar NNS cord-006870-f5w6fw6q 3773 24 spent spend VBN cord-006870-f5w6fw6q 3773 25 on on IN cord-006870-f5w6fw6q 3773 26 preventable preventable JJ cord-006870-f5w6fw6q 3773 27 hospital hospital NN cord-006870-f5w6fw6q 3773 28 acquired acquire VBN cord-006870-f5w6fw6q 3773 29 infections infection NNS cord-006870-f5w6fw6q 3773 30 . . . cord-006870-f5w6fw6q 3774 1 Intensive intensive JJ cord-006870-f5w6fw6q 3774 2 care care NN cord-006870-f5w6fw6q 3774 3 patients patient NNS cord-006870-f5w6fw6q 3774 4 , , , cord-006870-f5w6fw6q 3774 5 especially especially RB cord-006870-f5w6fw6q 3774 6 the the DT cord-006870-f5w6fw6q 3774 7 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3774 8 care care NN cord-006870-f5w6fw6q 3774 9 population population NN cord-006870-f5w6fw6q 3774 10 , , , cord-006870-f5w6fw6q 3774 11 have have VBP cord-006870-f5w6fw6q 3774 12 an an DT cord-006870-f5w6fw6q 3774 13 increased increase VBN cord-006870-f5w6fw6q 3774 14 need need NN cord-006870-f5w6fw6q 3774 15 for for IN cord-006870-f5w6fw6q 3774 16 centrally centrally RB cord-006870-f5w6fw6q 3774 17 placed place VBN cord-006870-f5w6fw6q 3774 18 catheters catheter NNS cord-006870-f5w6fw6q 3774 19 related relate VBN cord-006870-f5w6fw6q 3774 20 to to IN cord-006870-f5w6fw6q 3774 21 inadequacy inadequacy NN cord-006870-f5w6fw6q 3774 22 of of IN cord-006870-f5w6fw6q 3774 23 peripheral peripheral JJ cord-006870-f5w6fw6q 3774 24 access access NN cord-006870-f5w6fw6q 3774 25 , , , cord-006870-f5w6fw6q 3774 26 need need VBP cord-006870-f5w6fw6q 3774 27 for for IN cord-006870-f5w6fw6q 3774 28 caustic caustic JJ cord-006870-f5w6fw6q 3774 29 IV IV NNP cord-006870-f5w6fw6q 3774 30 medications medication NNS cord-006870-f5w6fw6q 3774 31 , , , cord-006870-f5w6fw6q 3774 32 and and CC cord-006870-f5w6fw6q 3774 33 fluid fluid JJ cord-006870-f5w6fw6q 3774 34 resuscitation resuscitation NN cord-006870-f5w6fw6q 3774 35 . . . cord-006870-f5w6fw6q 3775 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3775 2 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 3775 3 's 's POS cord-006870-f5w6fw6q 3775 4 goal goal NN cord-006870-f5w6fw6q 3775 5 was be VBD cord-006870-f5w6fw6q 3775 6 to to TO cord-006870-f5w6fw6q 3775 7 decrease decrease VB cord-006870-f5w6fw6q 3775 8 utilization utilization NN cord-006870-f5w6fw6q 3775 9 and and CC cord-006870-f5w6fw6q 3775 10 subsequently subsequently RB cord-006870-f5w6fw6q 3775 11 reduce reduce VB cord-006870-f5w6fw6q 3775 12 number number NN cord-006870-f5w6fw6q 3775 13 of of IN cord-006870-f5w6fw6q 3775 14 CLABSIs clabsi NNS cord-006870-f5w6fw6q 3775 15 . . . cord-006870-f5w6fw6q 3776 1 In in IN cord-006870-f5w6fw6q 3776 2 February February NNP cord-006870-f5w6fw6q 3776 3 2016 2016 CD cord-006870-f5w6fw6q 3776 4 , , , cord-006870-f5w6fw6q 3776 5 we -PRON- PRP cord-006870-f5w6fw6q 3776 6 initiated initiate VBD cord-006870-f5w6fw6q 3776 7 a a DT cord-006870-f5w6fw6q 3776 8 patient patient NN cord-006870-f5w6fw6q 3776 9 - - HYPH cord-006870-f5w6fw6q 3776 10 centered center VBN cord-006870-f5w6fw6q 3776 11 quality quality NN cord-006870-f5w6fw6q 3776 12 improvement improvement NN cord-006870-f5w6fw6q 3776 13 effort effort NN cord-006870-f5w6fw6q 3776 14 with with IN cord-006870-f5w6fw6q 3776 15 this this DT cord-006870-f5w6fw6q 3776 16 goal goal NN cord-006870-f5w6fw6q 3776 17 in in IN cord-006870-f5w6fw6q 3776 18 mind mind NN cord-006870-f5w6fw6q 3776 19 . . . cord-006870-f5w6fw6q 3777 1 The the DT cord-006870-f5w6fw6q 3777 2 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 3777 3 Clinical Clinical NNP cord-006870-f5w6fw6q 3777 4 Nurse Nurse NNP cord-006870-f5w6fw6q 3777 5 leaders leader NNS cord-006870-f5w6fw6q 3777 6 conducted conduct VBD cord-006870-f5w6fw6q 3777 7 rounds round NNS cord-006870-f5w6fw6q 3777 8 daily daily RB cord-006870-f5w6fw6q 3777 9 to to TO cord-006870-f5w6fw6q 3777 10 evaluate evaluate VB cord-006870-f5w6fw6q 3777 11 the the DT cord-006870-f5w6fw6q 3777 12 necessity necessity NN cord-006870-f5w6fw6q 3777 13 and and CC cord-006870-f5w6fw6q 3777 14 management management NN cord-006870-f5w6fw6q 3777 15 of of IN cord-006870-f5w6fw6q 3777 16 central central JJ cord-006870-f5w6fw6q 3777 17 lines line NNS cord-006870-f5w6fw6q 3777 18 . . . cord-006870-f5w6fw6q 3778 1 The the DT cord-006870-f5w6fw6q 3778 2 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3778 3 care care NN cord-006870-f5w6fw6q 3778 4 team team NN cord-006870-f5w6fw6q 3778 5 and and CC cord-006870-f5w6fw6q 3778 6 clinical clinical JJ cord-006870-f5w6fw6q 3778 7 nurse nurse NN cord-006870-f5w6fw6q 3778 8 leaders leader NNS cord-006870-f5w6fw6q 3778 9 collaborated collaborate VBD cord-006870-f5w6fw6q 3778 10 in in IN cord-006870-f5w6fw6q 3778 11 exploring explore VBG cord-006870-f5w6fw6q 3778 12 alternatives alternative NNS cord-006870-f5w6fw6q 3778 13 if if IN cord-006870-f5w6fw6q 3778 14 central central JJ cord-006870-f5w6fw6q 3778 15 lines line NNS cord-006870-f5w6fw6q 3778 16 were be VBD cord-006870-f5w6fw6q 3778 17 present present JJ cord-006870-f5w6fw6q 3778 18 . . . cord-006870-f5w6fw6q 3779 1 In in IN cord-006870-f5w6fw6q 3779 2 addition addition NN cord-006870-f5w6fw6q 3779 3 to to IN cord-006870-f5w6fw6q 3779 4 daily daily JJ cord-006870-f5w6fw6q 3779 5 rounding round VBG cord-006870-f5w6fw6q 3779 6 , , , cord-006870-f5w6fw6q 3779 7 CLABSI CLABSI NNP cord-006870-f5w6fw6q 3779 8 bundles bundle NNS cord-006870-f5w6fw6q 3779 9 based base VBN cord-006870-f5w6fw6q 3779 10 on on IN cord-006870-f5w6fw6q 3779 11 CDC CDC NNP cord-006870-f5w6fw6q 3779 12 guidelines guideline NNS cord-006870-f5w6fw6q 3779 13 for for IN cord-006870-f5w6fw6q 3779 14 CLABSI CLABSI NNP cord-006870-f5w6fw6q 3779 15 prevention prevention NN cord-006870-f5w6fw6q 3779 16 were be VBD cord-006870-f5w6fw6q 3779 17 initiated initiate VBN cord-006870-f5w6fw6q 3779 18 . . . cord-006870-f5w6fw6q 3780 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 3780 2 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 3780 3 developed develop VBD cord-006870-f5w6fw6q 3780 4 checklist checklist NN cord-006870-f5w6fw6q 3780 5 " " `` cord-006870-f5w6fw6q 3780 6 Buster Buster NNP cord-006870-f5w6fw6q 3780 7 Cards Cards NNP cord-006870-f5w6fw6q 3780 8 " " '' cord-006870-f5w6fw6q 3780 9 in in IN cord-006870-f5w6fw6q 3780 10 September September NNP cord-006870-f5w6fw6q 3780 11 of of IN cord-006870-f5w6fw6q 3780 12 2016 2016 CD cord-006870-f5w6fw6q 3780 13 , , , cord-006870-f5w6fw6q 3780 14 prompting prompt VBG cord-006870-f5w6fw6q 3780 15 staff staff NN cord-006870-f5w6fw6q 3780 16 to to IN cord-006870-f5w6fw6q 3780 17 the the DT cord-006870-f5w6fw6q 3780 18 bundle bundle NN cord-006870-f5w6fw6q 3780 19 interventions intervention NNS cord-006870-f5w6fw6q 3780 20 . . . cord-006870-f5w6fw6q 3781 1 The the DT cord-006870-f5w6fw6q 3781 2 intent intent NN cord-006870-f5w6fw6q 3781 3 of of IN cord-006870-f5w6fw6q 3781 4 the the DT cord-006870-f5w6fw6q 3781 5 cards card NNS cord-006870-f5w6fw6q 3781 6 was be VBD cord-006870-f5w6fw6q 3781 7 to to TO cord-006870-f5w6fw6q 3781 8 enhance enhance VB cord-006870-f5w6fw6q 3781 9 nurse nurse NN cord-006870-f5w6fw6q 3781 10 to to IN cord-006870-f5w6fw6q 3781 11 nurse nurse NN cord-006870-f5w6fw6q 3781 12 dialogue dialogue NN cord-006870-f5w6fw6q 3781 13 of of IN cord-006870-f5w6fw6q 3781 14 bundle bundle NN cord-006870-f5w6fw6q 3781 15 elements element NNS cord-006870-f5w6fw6q 3781 16 . . . cord-006870-f5w6fw6q 3782 1 The the DT cord-006870-f5w6fw6q 3782 2 cards card NNS cord-006870-f5w6fw6q 3782 3 were be VBD cord-006870-f5w6fw6q 3782 4 evaluated evaluate VBN cord-006870-f5w6fw6q 3782 5 monthly monthly RB cord-006870-f5w6fw6q 3782 6 for for IN cord-006870-f5w6fw6q 3782 7 trends trend NNS cord-006870-f5w6fw6q 3782 8 in in IN cord-006870-f5w6fw6q 3782 9 care care NN cord-006870-f5w6fw6q 3782 10 . . . cord-006870-f5w6fw6q 3783 1 From from IN cord-006870-f5w6fw6q 3783 2 August August NNP cord-006870-f5w6fw6q 3783 3 2015-June 2015-june CD cord-006870-f5w6fw6q 3783 4 2017 2017 CD cord-006870-f5w6fw6q 3783 5 , , , cord-006870-f5w6fw6q 3783 6 there there EX cord-006870-f5w6fw6q 3783 7 was be VBD cord-006870-f5w6fw6q 3783 8 a a DT cord-006870-f5w6fw6q 3783 9 15 15 CD cord-006870-f5w6fw6q 3783 10 % % NN cord-006870-f5w6fw6q 3783 11 reduction reduction NN cord-006870-f5w6fw6q 3783 12 in in IN cord-006870-f5w6fw6q 3783 13 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 3783 14 utilization utilization NN cord-006870-f5w6fw6q 3783 15 of of IN cord-006870-f5w6fw6q 3783 16 central central JJ cord-006870-f5w6fw6q 3783 17 lines line NNS cord-006870-f5w6fw6q 3783 18 . . . cord-006870-f5w6fw6q 3784 1 In in IN cord-006870-f5w6fw6q 3784 2 addition addition NN cord-006870-f5w6fw6q 3784 3 , , , cord-006870-f5w6fw6q 3784 4 the the DT cord-006870-f5w6fw6q 3784 5 mean mean JJ cord-006870-f5w6fw6q 3784 6 number number NN cord-006870-f5w6fw6q 3784 7 of of IN cord-006870-f5w6fw6q 3784 8 CLABSIs clabsi NNS cord-006870-f5w6fw6q 3784 9 per per IN cord-006870-f5w6fw6q 3784 10 month month NN cord-006870-f5w6fw6q 3784 11 decreased decrease VBD cord-006870-f5w6fw6q 3784 12 from from IN cord-006870-f5w6fw6q 3784 13 0.67 0.67 CD cord-006870-f5w6fw6q 3784 14 to to IN cord-006870-f5w6fw6q 3784 15 0.22 0.22 CD cord-006870-f5w6fw6q 3784 16 . . . cord-006870-f5w6fw6q 3785 1 Trending trend VBG cord-006870-f5w6fw6q 3785 2 of of IN cord-006870-f5w6fw6q 3785 3 unit unit NN cord-006870-f5w6fw6q 3785 4 Buster Buster NNP cord-006870-f5w6fw6q 3785 5 Cards Cards NNP cord-006870-f5w6fw6q 3785 6 did do VBD cord-006870-f5w6fw6q 3785 7 not not RB cord-006870-f5w6fw6q 3785 8 show show VB cord-006870-f5w6fw6q 3785 9 care care NN cord-006870-f5w6fw6q 3785 10 variances variance NNS cord-006870-f5w6fw6q 3785 11 during during IN cord-006870-f5w6fw6q 3785 12 this this DT cord-006870-f5w6fw6q 3785 13 time time NN cord-006870-f5w6fw6q 3785 14 period period NN cord-006870-f5w6fw6q 3785 15 . . . cord-006870-f5w6fw6q 3786 1 Implementing implement VBG cord-006870-f5w6fw6q 3786 2 daily daily JJ cord-006870-f5w6fw6q 3786 3 Clinical clinical JJ cord-006870-f5w6fw6q 3786 4 Nurse Nurse NNP cord-006870-f5w6fw6q 3786 5 Leader Leader NNP cord-006870-f5w6fw6q 3786 6 rounds round NNS cord-006870-f5w6fw6q 3786 7 with with IN cord-006870-f5w6fw6q 3786 8 enhanced enhanced JJ cord-006870-f5w6fw6q 3786 9 team team NN cord-006870-f5w6fw6q 3786 10 communication communication NN cord-006870-f5w6fw6q 3786 11 significantly significantly RB cord-006870-f5w6fw6q 3786 12 reduced reduce VBD cord-006870-f5w6fw6q 3786 13 the the DT cord-006870-f5w6fw6q 3786 14 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 3786 15 's 's POS cord-006870-f5w6fw6q 3786 16 utilization utilization NN cord-006870-f5w6fw6q 3786 17 of of IN cord-006870-f5w6fw6q 3786 18 central central JJ cord-006870-f5w6fw6q 3786 19 lines line NNS cord-006870-f5w6fw6q 3786 20 and and CC cord-006870-f5w6fw6q 3786 21 thereby thereby RB cord-006870-f5w6fw6q 3786 22 decreased decrease VBD cord-006870-f5w6fw6q 3786 23 the the DT cord-006870-f5w6fw6q 3786 24 rate rate NN cord-006870-f5w6fw6q 3786 25 of of IN cord-006870-f5w6fw6q 3786 26 CLABSIs clabsi NNS cord-006870-f5w6fw6q 3786 27 . . . cord-006870-f5w6fw6q 3787 1 Percutaneous Percutaneous NNP cord-006870-f5w6fw6q 3787 2 dilatational dilatational JJ cord-006870-f5w6fw6q 3787 3 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 3787 4 ( ( -LRB- cord-006870-f5w6fw6q 3787 5 PDT PDT NNP cord-006870-f5w6fw6q 3787 6 ) ) -RRB- cord-006870-f5w6fw6q 3787 7 is be VBZ cord-006870-f5w6fw6q 3787 8 one one CD cord-006870-f5w6fw6q 3787 9 of of IN cord-006870-f5w6fw6q 3787 10 the the DT cord-006870-f5w6fw6q 3787 11 most most RBS cord-006870-f5w6fw6q 3787 12 commonly commonly RB cord-006870-f5w6fw6q 3787 13 performed perform VBN cord-006870-f5w6fw6q 3787 14 procedures procedure NNS cord-006870-f5w6fw6q 3787 15 on on IN cord-006870-f5w6fw6q 3787 16 critically critically RB cord-006870-f5w6fw6q 3787 17 ill ill JJ cord-006870-f5w6fw6q 3787 18 patients patient NNS cord-006870-f5w6fw6q 3787 19 . . . cord-006870-f5w6fw6q 3788 1 Many many JJ cord-006870-f5w6fw6q 3788 2 studies study NNS cord-006870-f5w6fw6q 3788 3 showed show VBD cord-006870-f5w6fw6q 3788 4 the the DT cord-006870-f5w6fw6q 3788 5 safety safety NN cord-006870-f5w6fw6q 3788 6 and and CC cord-006870-f5w6fw6q 3788 7 feasibility feasibility NN cord-006870-f5w6fw6q 3788 8 of of IN cord-006870-f5w6fw6q 3788 9 PDT PDT NNP cord-006870-f5w6fw6q 3788 10 , , , cord-006870-f5w6fw6q 3788 11 but but CC cord-006870-f5w6fw6q 3788 12 there there EX cord-006870-f5w6fw6q 3788 13 is be VBZ cord-006870-f5w6fw6q 3788 14 limited limited JJ cord-006870-f5w6fw6q 3788 15 data datum NNS cord-006870-f5w6fw6q 3788 16 of of IN cord-006870-f5w6fw6q 3788 17 PDT PDT NNP cord-006870-f5w6fw6q 3788 18 in in IN cord-006870-f5w6fw6q 3788 19 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3788 20 care care NN cord-006870-f5w6fw6q 3788 21 units unit NNS cord-006870-f5w6fw6q 3788 22 . . . cord-006870-f5w6fw6q 3789 1 We -PRON- PRP cord-006870-f5w6fw6q 3789 2 have have VBP cord-006870-f5w6fw6q 3789 3 described describe VBN cord-006870-f5w6fw6q 3789 4 our -PRON- PRP$ cord-006870-f5w6fw6q 3789 5 experience experience NN cord-006870-f5w6fw6q 3789 6 of of IN cord-006870-f5w6fw6q 3789 7 PDT PDT NNP cord-006870-f5w6fw6q 3789 8 performed perform VBN cord-006870-f5w6fw6q 3789 9 by by IN cord-006870-f5w6fw6q 3789 10 neurointensivist neurointensivist NNP cord-006870-f5w6fw6q 3789 11 . . . cord-006870-f5w6fw6q 3790 1 PDTs pdt NNS cord-006870-f5w6fw6q 3790 2 were be VBD cord-006870-f5w6fw6q 3790 3 performed perform VBN cord-006870-f5w6fw6q 3790 4 by by IN cord-006870-f5w6fw6q 3790 5 neurointensivists neurointensivist NNS cord-006870-f5w6fw6q 3790 6 at at IN cord-006870-f5w6fw6q 3790 7 bedside bedside NN cord-006870-f5w6fw6q 3790 8 using use VBG cord-006870-f5w6fw6q 3790 9 the the DT cord-006870-f5w6fw6q 3790 10 Griggs Griggs NNP cord-006870-f5w6fw6q 3790 11 guide guide NN cord-006870-f5w6fw6q 3790 12 wire wire NN cord-006870-f5w6fw6q 3790 13 dilating dilate VBG cord-006870-f5w6fw6q 3790 14 forceps forceps NNS cord-006870-f5w6fw6q 3790 15 technique technique NN cord-006870-f5w6fw6q 3790 16 . . . cord-006870-f5w6fw6q 3791 1 To to TO cord-006870-f5w6fw6q 3791 2 confirm confirm VB cord-006870-f5w6fw6q 3791 3 a a DT cord-006870-f5w6fw6q 3791 4 secure secure JJ cord-006870-f5w6fw6q 3791 5 puncture puncture NN cord-006870-f5w6fw6q 3791 6 site site NN cord-006870-f5w6fw6q 3791 7 , , , cord-006870-f5w6fw6q 3791 8 PDT PDT NNP cord-006870-f5w6fw6q 3791 9 was be VBD cord-006870-f5w6fw6q 3791 10 done do VBN cord-006870-f5w6fw6q 3791 11 under under IN cord-006870-f5w6fw6q 3791 12 fiberoptic fiberoptic JJ cord-006870-f5w6fw6q 3791 13 bronchoscopic bronchoscopic NNP cord-006870-f5w6fw6q 3791 14 guidance guidance NN cord-006870-f5w6fw6q 3791 15 . . . cord-006870-f5w6fw6q 3792 1 From from IN cord-006870-f5w6fw6q 3792 2 September September NNP cord-006870-f5w6fw6q 3792 3 2015 2015 CD cord-006870-f5w6fw6q 3792 4 to to IN cord-006870-f5w6fw6q 3792 5 May May NNP cord-006870-f5w6fw6q 3792 6 2017 2017 CD cord-006870-f5w6fw6q 3792 7 , , , cord-006870-f5w6fw6q 3792 8 procedural procedural JJ cord-006870-f5w6fw6q 3792 9 data datum NNS cord-006870-f5w6fw6q 3792 10 were be VBD cord-006870-f5w6fw6q 3792 11 prospectively prospectively RB cord-006870-f5w6fw6q 3792 12 collected collect VBN cord-006870-f5w6fw6q 3792 13 . . . cord-006870-f5w6fw6q 3793 1 The the DT cord-006870-f5w6fw6q 3793 2 patients patient NNS cord-006870-f5w6fw6q 3793 3 ' ' POS cord-006870-f5w6fw6q 3793 4 demographic demographic JJ cord-006870-f5w6fw6q 3793 5 and and CC cord-006870-f5w6fw6q 3793 6 clinical clinical JJ cord-006870-f5w6fw6q 3793 7 characteristics characteristic NNS cord-006870-f5w6fw6q 3793 8 were be VBD cord-006870-f5w6fw6q 3793 9 retrospectively retrospectively RB cord-006870-f5w6fw6q 3793 10 reviewed review VBN cord-006870-f5w6fw6q 3793 11 . . . cord-006870-f5w6fw6q 3794 1 We -PRON- PRP cord-006870-f5w6fw6q 3794 2 analyzed analyze VBD cord-006870-f5w6fw6q 3794 3 immediate immediate JJ cord-006870-f5w6fw6q 3794 4 complications complication NNS cord-006870-f5w6fw6q 3794 5 of of IN cord-006870-f5w6fw6q 3794 6 PDT PDT NNP cord-006870-f5w6fw6q 3794 7 as as IN cord-006870-f5w6fw6q 3794 8 the the DT cord-006870-f5w6fw6q 3794 9 primary primary JJ cord-006870-f5w6fw6q 3794 10 outcome outcome NN cord-006870-f5w6fw6q 3794 11 . . . cord-006870-f5w6fw6q 3795 1 PDTs pdt NNS cord-006870-f5w6fw6q 3795 2 were be VBD cord-006870-f5w6fw6q 3795 3 performed perform VBN cord-006870-f5w6fw6q 3795 4 for for IN cord-006870-f5w6fw6q 3795 5 46 46 CD cord-006870-f5w6fw6q 3795 6 patients patient NNS cord-006870-f5w6fw6q 3795 7 ; ; : cord-006870-f5w6fw6q 3795 8 the the DT cord-006870-f5w6fw6q 3795 9 mean mean JJ cord-006870-f5w6fw6q 3795 10 age age NN cord-006870-f5w6fw6q 3795 11 was be VBD cord-006870-f5w6fw6q 3795 12 65.9 65.9 CD cord-006870-f5w6fw6q 3795 13 years year NNS cord-006870-f5w6fw6q 3795 14 , , , cord-006870-f5w6fw6q 3795 15 26 26 CD cord-006870-f5w6fw6q 3795 16 ( ( -LRB- cord-006870-f5w6fw6q 3795 17 56.5 56.5 CD cord-006870-f5w6fw6q 3795 18 % % NN cord-006870-f5w6fw6q 3795 19 ) ) -RRB- cord-006870-f5w6fw6q 3795 20 were be VBD cord-006870-f5w6fw6q 3795 21 male male JJ cord-006870-f5w6fw6q 3795 22 , , , cord-006870-f5w6fw6q 3795 23 and and CC cord-006870-f5w6fw6q 3795 24 mean mean VB cord-006870-f5w6fw6q 3795 25 acute acute JJ cord-006870-f5w6fw6q 3795 26 physiology physiology NN cord-006870-f5w6fw6q 3795 27 and and CC cord-006870-f5w6fw6q 3795 28 chronic chronic JJ cord-006870-f5w6fw6q 3795 29 health health NN cord-006870-f5w6fw6q 3795 30 evaluation evaluation NN cord-006870-f5w6fw6q 3795 31 II II NNP cord-006870-f5w6fw6q 3795 32 score score NN cord-006870-f5w6fw6q 3795 33 was be VBD cord-006870-f5w6fw6q 3795 34 20.5 20.5 CD cord-006870-f5w6fw6q 3795 35 ± ± NNP cord-006870-f5w6fw6q 3795 36 7.0 7.0 CD cord-006870-f5w6fw6q 3795 37 . . . cord-006870-f5w6fw6q 3796 1 Overall overall RB cord-006870-f5w6fw6q 3796 2 , , , cord-006870-f5w6fw6q 3796 3 the the DT cord-006870-f5w6fw6q 3796 4 procedural procedural JJ cord-006870-f5w6fw6q 3796 5 success success NN cord-006870-f5w6fw6q 3796 6 rate rate NN cord-006870-f5w6fw6q 3796 7 was be VBD cord-006870-f5w6fw6q 3796 8 100 100 CD cord-006870-f5w6fw6q 3796 9 % % NN cord-006870-f5w6fw6q 3796 10 and and CC cord-006870-f5w6fw6q 3796 11 the the DT cord-006870-f5w6fw6q 3796 12 mean mean JJ cord-006870-f5w6fw6q 3796 13 procedural procedural JJ cord-006870-f5w6fw6q 3796 14 time time NN cord-006870-f5w6fw6q 3796 15 was be VBD cord-006870-f5w6fw6q 3796 16 19.7 19.7 CD cord-006870-f5w6fw6q 3796 17 ± ± CD cord-006870-f5w6fw6q 3796 18 9.3 9.3 CD cord-006870-f5w6fw6q 3796 19 min min NN cord-006870-f5w6fw6q 3796 20 . . . cord-006870-f5w6fw6q 3797 1 Periprocedural periprocedural JJ cord-006870-f5w6fw6q 3797 2 complications complication NNS cord-006870-f5w6fw6q 3797 3 occurred occur VBD cord-006870-f5w6fw6q 3797 4 in in IN cord-006870-f5w6fw6q 3797 5 13 13 CD cord-006870-f5w6fw6q 3797 6 patients patient NNS cord-006870-f5w6fw6q 3797 7 ; ; : cord-006870-f5w6fw6q 3797 8 10 10 CD cord-006870-f5w6fw6q 3797 9 had have VBD cord-006870-f5w6fw6q 3797 10 minor minor JJ cord-006870-f5w6fw6q 3797 11 bleeding bleeding NN cord-006870-f5w6fw6q 3797 12 and and CC cord-006870-f5w6fw6q 3797 13 3 3 CD cord-006870-f5w6fw6q 3797 14 had have VBD cord-006870-f5w6fw6q 3797 15 tracheal tracheal JJ cord-006870-f5w6fw6q 3797 16 ring ring NN cord-006870-f5w6fw6q 3797 17 fracture fracture NN cord-006870-f5w6fw6q 3797 18 . . . cord-006870-f5w6fw6q 3798 1 There there EX cord-006870-f5w6fw6q 3798 2 were be VBD cord-006870-f5w6fw6q 3798 3 no no DT cord-006870-f5w6fw6q 3798 4 serious serious JJ cord-006870-f5w6fw6q 3798 5 periprocedural periprocedural JJ cord-006870-f5w6fw6q 3798 6 complications complication NNS cord-006870-f5w6fw6q 3798 7 of of IN cord-006870-f5w6fw6q 3798 8 PDT PDT NNP cord-006870-f5w6fw6q 3798 9 . . . cord-006870-f5w6fw6q 3799 1 From from IN cord-006870-f5w6fw6q 3799 2 our -PRON- PRP$ cord-006870-f5w6fw6q 3799 3 experience experience NN cord-006870-f5w6fw6q 3799 4 , , , cord-006870-f5w6fw6q 3799 5 PDT PDT NNP cord-006870-f5w6fw6q 3799 6 performed perform VBN cord-006870-f5w6fw6q 3799 7 by by IN cord-006870-f5w6fw6q 3799 8 neurointensivist neurointensivist NNP cord-006870-f5w6fw6q 3799 9 was be VBD cord-006870-f5w6fw6q 3799 10 safe safe JJ cord-006870-f5w6fw6q 3799 11 and and CC cord-006870-f5w6fw6q 3799 12 feasible feasible JJ cord-006870-f5w6fw6q 3799 13 and and CC cord-006870-f5w6fw6q 3799 14 was be VBD cord-006870-f5w6fw6q 3799 15 implemented implement VBN cord-006870-f5w6fw6q 3799 16 without without IN cord-006870-f5w6fw6q 3799 17 serious serious JJ cord-006870-f5w6fw6q 3799 18 complications complication NNS cord-006870-f5w6fw6q 3799 19 . . . cord-006870-f5w6fw6q 3800 1 The the DT cord-006870-f5w6fw6q 3800 2 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3800 3 Care Care NNP cord-006870-f5w6fw6q 3800 4 Unit Unit NNP cord-006870-f5w6fw6q 3800 5 ( ( -LRB- cord-006870-f5w6fw6q 3800 6 NCCU NCCU NNP cord-006870-f5w6fw6q 3800 7 ) ) -RRB- cord-006870-f5w6fw6q 3800 8 is be VBZ cord-006870-f5w6fw6q 3800 9 a a DT cord-006870-f5w6fw6q 3800 10 fast fast JJ cord-006870-f5w6fw6q 3800 11 paced pace VBN cord-006870-f5w6fw6q 3800 12 setting setting NN cord-006870-f5w6fw6q 3800 13 with with IN cord-006870-f5w6fw6q 3800 14 a a DT cord-006870-f5w6fw6q 3800 15 multitude multitude NN cord-006870-f5w6fw6q 3800 16 of of IN cord-006870-f5w6fw6q 3800 17 providers provider NNS cord-006870-f5w6fw6q 3800 18 and and CC cord-006870-f5w6fw6q 3800 19 team team NN cord-006870-f5w6fw6q 3800 20 members member NNS cord-006870-f5w6fw6q 3800 21 requiring require VBG cord-006870-f5w6fw6q 3800 22 optimal optimal JJ cord-006870-f5w6fw6q 3800 23 communication communication NN cord-006870-f5w6fw6q 3800 24 . . . cord-006870-f5w6fw6q 3801 1 It -PRON- PRP cord-006870-f5w6fw6q 3801 2 is be VBZ cord-006870-f5w6fw6q 3801 3 also also RB cord-006870-f5w6fw6q 3801 4 a a DT cord-006870-f5w6fw6q 3801 5 high high JJ cord-006870-f5w6fw6q 3801 6 cost cost NN cord-006870-f5w6fw6q 3801 7 / / SYM cord-006870-f5w6fw6q 3801 8 high high JJ cord-006870-f5w6fw6q 3801 9 utilization utilization NN cord-006870-f5w6fw6q 3801 10 environment environment NN cord-006870-f5w6fw6q 3801 11 , , , cord-006870-f5w6fw6q 3801 12 dictating dictate VBG cord-006870-f5w6fw6q 3801 13 the the DT cord-006870-f5w6fw6q 3801 14 need need NN cord-006870-f5w6fw6q 3801 15 for for IN cord-006870-f5w6fw6q 3801 16 patients patient NNS cord-006870-f5w6fw6q 3801 17 to to TO cord-006870-f5w6fw6q 3801 18 be be VB cord-006870-f5w6fw6q 3801 19 moved move VBN cord-006870-f5w6fw6q 3801 20 thru thru IN cord-006870-f5w6fw6q 3801 21 appropriate appropriate JJ cord-006870-f5w6fw6q 3801 22 levels level NNS cord-006870-f5w6fw6q 3801 23 of of IN cord-006870-f5w6fw6q 3801 24 care care NN cord-006870-f5w6fw6q 3801 25 efficiently efficiently RB cord-006870-f5w6fw6q 3801 26 . . . cord-006870-f5w6fw6q 3802 1 All all DT cord-006870-f5w6fw6q 3802 2 of of IN cord-006870-f5w6fw6q 3802 3 this this DT cord-006870-f5w6fw6q 3802 4 must must MD cord-006870-f5w6fw6q 3802 5 be be VB cord-006870-f5w6fw6q 3802 6 accomplished accomplish VBN cord-006870-f5w6fw6q 3802 7 while while IN cord-006870-f5w6fw6q 3802 8 providing provide VBG cord-006870-f5w6fw6q 3802 9 support support NN cord-006870-f5w6fw6q 3802 10 and and CC cord-006870-f5w6fw6q 3802 11 opportunity opportunity NN cord-006870-f5w6fw6q 3802 12 for for IN cord-006870-f5w6fw6q 3802 13 collaboration collaboration NN cord-006870-f5w6fw6q 3802 14 and and CC cord-006870-f5w6fw6q 3802 15 decision decision NN cord-006870-f5w6fw6q 3802 16 making making NN cord-006870-f5w6fw6q 3802 17 on on IN cord-006870-f5w6fw6q 3802 18 the the DT cord-006870-f5w6fw6q 3802 19 part part NN cord-006870-f5w6fw6q 3802 20 of of IN cord-006870-f5w6fw6q 3802 21 the the DT cord-006870-f5w6fw6q 3802 22 patient/ patient/ NNP cord-006870-f5w6fw6q 3802 23 family family NN cord-006870-f5w6fw6q 3802 24 unit unit NN cord-006870-f5w6fw6q 3802 25 . . . cord-006870-f5w6fw6q 3803 1 There there EX cord-006870-f5w6fw6q 3803 2 is be VBZ cord-006870-f5w6fw6q 3803 3 great great JJ cord-006870-f5w6fw6q 3803 4 discussion discussion NN cord-006870-f5w6fw6q 3803 5 in in IN cord-006870-f5w6fw6q 3803 6 the the DT cord-006870-f5w6fw6q 3803 7 case case NN cord-006870-f5w6fw6q 3803 8 management management NN cord-006870-f5w6fw6q 3803 9 world world NN cord-006870-f5w6fw6q 3803 10 about about IN cord-006870-f5w6fw6q 3803 11 the the DT cord-006870-f5w6fw6q 3803 12 benefits benefit NNS cord-006870-f5w6fw6q 3803 13 of of IN cord-006870-f5w6fw6q 3803 14 a a DT cord-006870-f5w6fw6q 3803 15 unit unit NN cord-006870-f5w6fw6q 3803 16 based base VBN cord-006870-f5w6fw6q 3803 17 verses verses IN cord-006870-f5w6fw6q 3803 18 service service NN cord-006870-f5w6fw6q 3803 19 based base VBN cord-006870-f5w6fw6q 3803 20 case case NN cord-006870-f5w6fw6q 3803 21 management management NN cord-006870-f5w6fw6q 3803 22 model model NN cord-006870-f5w6fw6q 3803 23 . . . cord-006870-f5w6fw6q 3804 1 We -PRON- PRP cord-006870-f5w6fw6q 3804 2 looked look VBD cord-006870-f5w6fw6q 3804 3 at at IN cord-006870-f5w6fw6q 3804 4 outcomes outcome NNS cord-006870-f5w6fw6q 3804 5 following follow VBG cord-006870-f5w6fw6q 3804 6 the the DT cord-006870-f5w6fw6q 3804 7 implementation implementation NN cord-006870-f5w6fw6q 3804 8 of of IN cord-006870-f5w6fw6q 3804 9 a a DT cord-006870-f5w6fw6q 3804 10 unit unit NN cord-006870-f5w6fw6q 3804 11 based base VBN cord-006870-f5w6fw6q 3804 12 case case NN cord-006870-f5w6fw6q 3804 13 manager manager NN cord-006870-f5w6fw6q 3804 14 in in IN cord-006870-f5w6fw6q 3804 15 the the DT cord-006870-f5w6fw6q 3804 16 NCCU NCCU NNP cord-006870-f5w6fw6q 3804 17 . . . cord-006870-f5w6fw6q 3805 1 A a DT cord-006870-f5w6fw6q 3805 2 dedicated dedicated JJ cord-006870-f5w6fw6q 3805 3 Case Case NNP cord-006870-f5w6fw6q 3805 4 Manager Manager NNP cord-006870-f5w6fw6q 3805 5 ( ( -LRB- cord-006870-f5w6fw6q 3805 6 CM CM NNP cord-006870-f5w6fw6q 3805 7 ) ) -RRB- cord-006870-f5w6fw6q 3805 8 was be VBD cord-006870-f5w6fw6q 3805 9 implemented implement VBN cord-006870-f5w6fw6q 3805 10 in in IN cord-006870-f5w6fw6q 3805 11 the the DT cord-006870-f5w6fw6q 3805 12 NCCU NCCU NNP cord-006870-f5w6fw6q 3805 13 to to TO cord-006870-f5w6fw6q 3805 14 maximize maximize VB cord-006870-f5w6fw6q 3805 15 assessment assessment NN cord-006870-f5w6fw6q 3805 16 , , , cord-006870-f5w6fw6q 3805 17 advocacy advocacy NN cord-006870-f5w6fw6q 3805 18 , , , cord-006870-f5w6fw6q 3805 19 communication communication NN cord-006870-f5w6fw6q 3805 20 , , , cord-006870-f5w6fw6q 3805 21 education education NN cord-006870-f5w6fw6q 3805 22 , , , cord-006870-f5w6fw6q 3805 23 identification identification NN cord-006870-f5w6fw6q 3805 24 of of IN cord-006870-f5w6fw6q 3805 25 resources resource NNS cord-006870-f5w6fw6q 3805 26 , , , cord-006870-f5w6fw6q 3805 27 and and CC cord-006870-f5w6fw6q 3805 28 facilitation facilitation NN cord-006870-f5w6fw6q 3805 29 of of IN cord-006870-f5w6fw6q 3805 30 services service NNS cord-006870-f5w6fw6q 3805 31 . . . cord-006870-f5w6fw6q 3806 1 Processes process NNS cord-006870-f5w6fw6q 3806 2 to to TO cord-006870-f5w6fw6q 3806 3 support support VB cord-006870-f5w6fw6q 3806 4 maximal maximal JJ cord-006870-f5w6fw6q 3806 5 contributions contribution NNS cord-006870-f5w6fw6q 3806 6 were be VBD cord-006870-f5w6fw6q 3806 7 created create VBN cord-006870-f5w6fw6q 3806 8 . . . cord-006870-f5w6fw6q 3807 1 Interventions intervention NNS cord-006870-f5w6fw6q 3807 2 included include VBD cord-006870-f5w6fw6q 3807 3 use use NN cord-006870-f5w6fw6q 3807 4 of of IN cord-006870-f5w6fw6q 3807 5 a a DT cord-006870-f5w6fw6q 3807 6 discharge discharge NN cord-006870-f5w6fw6q 3807 7 planning planning NN cord-006870-f5w6fw6q 3807 8 worksheet worksheet NN cord-006870-f5w6fw6q 3807 9 , , , cord-006870-f5w6fw6q 3807 10 implementation implementation NN cord-006870-f5w6fw6q 3807 11 of of IN cord-006870-f5w6fw6q 3807 12 a a DT cord-006870-f5w6fw6q 3807 13 morning morning NN cord-006870-f5w6fw6q 3807 14 huddle huddle NN cord-006870-f5w6fw6q 3807 15 , , , cord-006870-f5w6fw6q 3807 16 and and CC cord-006870-f5w6fw6q 3807 17 space space NN cord-006870-f5w6fw6q 3807 18 for for IN cord-006870-f5w6fw6q 3807 19 the the DT cord-006870-f5w6fw6q 3807 20 case case NN cord-006870-f5w6fw6q 3807 21 manager manager NN cord-006870-f5w6fw6q 3807 22 to to TO cord-006870-f5w6fw6q 3807 23 be be VB cord-006870-f5w6fw6q 3807 24 physically physically RB cord-006870-f5w6fw6q 3807 25 available available JJ cord-006870-f5w6fw6q 3807 26 on on IN cord-006870-f5w6fw6q 3807 27 the the DT cord-006870-f5w6fw6q 3807 28 unit unit NN cord-006870-f5w6fw6q 3807 29 . . . cord-006870-f5w6fw6q 3808 1 LOS LOS NNP cord-006870-f5w6fw6q 3808 2 of of IN cord-006870-f5w6fw6q 3808 3 patients patient NNS cord-006870-f5w6fw6q 3808 4 discharged discharge VBN cord-006870-f5w6fw6q 3808 5 from from IN cord-006870-f5w6fw6q 3808 6 NCCU NCCU NNP cord-006870-f5w6fw6q 3808 7 decreased decrease VBD cord-006870-f5w6fw6q 3808 8 from from IN cord-006870-f5w6fw6q 3808 9 7.2 7.2 CD cord-006870-f5w6fw6q 3808 10 to to IN cord-006870-f5w6fw6q 3808 11 5.1 5.1 CD cord-006870-f5w6fw6q 3808 12 . . . cord-006870-f5w6fw6q 3809 1 ALOS ALOS NNP cord-006870-f5w6fw6q 3809 2 for for IN cord-006870-f5w6fw6q 3809 3 patients patient NNS cord-006870-f5w6fw6q 3809 4 that that WDT cord-006870-f5w6fw6q 3809 5 passed pass VBD cord-006870-f5w6fw6q 3809 6 thru thru IN cord-006870-f5w6fw6q 3809 7 the the DT cord-006870-f5w6fw6q 3809 8 NCCU NCCU NNP cord-006870-f5w6fw6q 3809 9 during during IN cord-006870-f5w6fw6q 3809 10 their -PRON- PRP$ cord-006870-f5w6fw6q 3809 11 hospitalization hospitalization NN cord-006870-f5w6fw6q 3809 12 decreased decrease VBD cord-006870-f5w6fw6q 3809 13 from from IN cord-006870-f5w6fw6q 3809 14 10.7 10.7 CD cord-006870-f5w6fw6q 3809 15 days day NNS cord-006870-f5w6fw6q 3809 16 to to IN cord-006870-f5w6fw6q 3809 17 9.2 9.2 CD cord-006870-f5w6fw6q 3809 18 . . . cord-006870-f5w6fw6q 3810 1 There there EX cord-006870-f5w6fw6q 3810 2 was be VBD cord-006870-f5w6fw6q 3810 3 a a DT cord-006870-f5w6fw6q 3810 4 38 38 CD cord-006870-f5w6fw6q 3810 5 % % NN cord-006870-f5w6fw6q 3810 6 increase increase NN cord-006870-f5w6fw6q 3810 7 in in IN cord-006870-f5w6fw6q 3810 8 discharges discharge NNS cord-006870-f5w6fw6q 3810 9 from from IN cord-006870-f5w6fw6q 3810 10 NCCU NCCU NNP cord-006870-f5w6fw6q 3810 11 from from IN cord-006870-f5w6fw6q 3810 12 2015 2015 CD cord-006870-f5w6fw6q 3810 13 to to IN cord-006870-f5w6fw6q 3810 14 2016 2016 CD cord-006870-f5w6fw6q 3810 15 . . . cord-006870-f5w6fw6q 3811 1 Average average JJ cord-006870-f5w6fw6q 3811 2 time time NN cord-006870-f5w6fw6q 3811 3 from from IN cord-006870-f5w6fw6q 3811 4 admission admission NN cord-006870-f5w6fw6q 3811 5 to to IN cord-006870-f5w6fw6q 3811 6 CM cm NN cord-006870-f5w6fw6q 3811 7 assessment assessment NN cord-006870-f5w6fw6q 3811 8 decreased decrease VBD cord-006870-f5w6fw6q 3811 9 from from IN cord-006870-f5w6fw6q 3811 10 51 51 CD cord-006870-f5w6fw6q 3811 11 hours hour NNS cord-006870-f5w6fw6q 3811 12 to to IN cord-006870-f5w6fw6q 3811 13 32.2 32.2 CD cord-006870-f5w6fw6q 3811 14 hours hour NNS cord-006870-f5w6fw6q 3811 15 . . . cord-006870-f5w6fw6q 3812 1 Progress progress NN cord-006870-f5w6fw6q 3812 2 notes note VBZ cord-006870-f5w6fw6q 3812 3 indicating indicate VBG cord-006870-f5w6fw6q 3812 4 intervention intervention NN cord-006870-f5w6fw6q 3812 5 and/or and/or CC cord-006870-f5w6fw6q 3812 6 communication communication NN cord-006870-f5w6fw6q 3812 7 of of IN cord-006870-f5w6fw6q 3812 8 the the DT cord-006870-f5w6fw6q 3812 9 plan plan NN cord-006870-f5w6fw6q 3812 10 increased increase VBD cord-006870-f5w6fw6q 3812 11 from from IN cord-006870-f5w6fw6q 3812 12 211 211 CD cord-006870-f5w6fw6q 3812 13 to to IN cord-006870-f5w6fw6q 3812 14 630 630 CD cord-006870-f5w6fw6q 3812 15 . . . cord-006870-f5w6fw6q 3813 1 Staff staff NN cord-006870-f5w6fw6q 3813 2 questionnaire questionnaire NN cord-006870-f5w6fw6q 3813 3 indicated indicate VBD cord-006870-f5w6fw6q 3813 4 increased increased JJ cord-006870-f5w6fw6q 3813 5 awareness awareness NN cord-006870-f5w6fw6q 3813 6 of of IN cord-006870-f5w6fw6q 3813 7 LOS LOS NNP cord-006870-f5w6fw6q 3813 8 and and CC cord-006870-f5w6fw6q 3813 9 dc dc NNP cord-006870-f5w6fw6q 3813 10 plan plan NNP cord-006870-f5w6fw6q 3813 11 needs need VBZ cord-006870-f5w6fw6q 3813 12 . . . cord-006870-f5w6fw6q 3814 1 In in IN cord-006870-f5w6fw6q 3814 2 this this DT cord-006870-f5w6fw6q 3814 3 Midwestern midwestern JJ cord-006870-f5w6fw6q 3814 4 , , , cord-006870-f5w6fw6q 3814 5 academic academic JJ cord-006870-f5w6fw6q 3814 6 medical medical JJ cord-006870-f5w6fw6q 3814 7 center center NN cord-006870-f5w6fw6q 3814 8 , , , cord-006870-f5w6fw6q 3814 9 integrating integrate VBG cord-006870-f5w6fw6q 3814 10 a a DT cord-006870-f5w6fw6q 3814 11 dedicated dedicated JJ cord-006870-f5w6fw6q 3814 12 , , , cord-006870-f5w6fw6q 3814 13 unit unit NN cord-006870-f5w6fw6q 3814 14 based base VBN cord-006870-f5w6fw6q 3814 15 CM CM NNP cord-006870-f5w6fw6q 3814 16 resulted result VBD cord-006870-f5w6fw6q 3814 17 in in IN cord-006870-f5w6fw6q 3814 18 improved improve VBN cord-006870-f5w6fw6q 3814 19 LOS LOS NNP cord-006870-f5w6fw6q 3814 20 , , , cord-006870-f5w6fw6q 3814 21 increased increase VBN cord-006870-f5w6fw6q 3814 22 discharges discharge NNS cord-006870-f5w6fw6q 3814 23 and and CC cord-006870-f5w6fw6q 3814 24 improved improved JJ cord-006870-f5w6fw6q 3814 25 staff staff NN cord-006870-f5w6fw6q 3814 26 awareness awareness NN cord-006870-f5w6fw6q 3814 27 of of IN cord-006870-f5w6fw6q 3814 28 DC DC NNP cord-006870-f5w6fw6q 3814 29 plans plan NNS cord-006870-f5w6fw6q 3814 30 . . . cord-006870-f5w6fw6q 3815 1 High high JJ cord-006870-f5w6fw6q 3815 2 throughput throughput NN cord-006870-f5w6fw6q 3815 3 genotyping genotyping NN cord-006870-f5w6fw6q 3815 4 technologies technology NNS cord-006870-f5w6fw6q 3815 5 and and CC cord-006870-f5w6fw6q 3815 6 large large JJ cord-006870-f5w6fw6q 3815 7 collaborative collaborative JJ cord-006870-f5w6fw6q 3815 8 consortia consortium NNS cord-006870-f5w6fw6q 3815 9 have have VBP cord-006870-f5w6fw6q 3815 10 revolutionized revolutionize VBN cord-006870-f5w6fw6q 3815 11 the the DT cord-006870-f5w6fw6q 3815 12 field field NN cord-006870-f5w6fw6q 3815 13 of of IN cord-006870-f5w6fw6q 3815 14 medical medical JJ cord-006870-f5w6fw6q 3815 15 genetics genetic NNS cord-006870-f5w6fw6q 3815 16 . . . cord-006870-f5w6fw6q 3816 1 Open open JJ cord-006870-f5w6fw6q 3816 2 data data NN cord-006870-f5w6fw6q 3816 3 access access NN cord-006870-f5w6fw6q 3816 4 is be VBZ cord-006870-f5w6fw6q 3816 5 the the DT cord-006870-f5w6fw6q 3816 6 final final JJ cord-006870-f5w6fw6q 3816 7 barrier barrier NN cord-006870-f5w6fw6q 3816 8 to to TO cord-006870-f5w6fw6q 3816 9 be be VB cord-006870-f5w6fw6q 3816 10 overcome overcome VBN cord-006870-f5w6fw6q 3816 11 to to TO cord-006870-f5w6fw6q 3816 12 capitalize capitalize VB cord-006870-f5w6fw6q 3816 13 fully fully RB cord-006870-f5w6fw6q 3816 14 on on IN cord-006870-f5w6fw6q 3816 15 the the DT cord-006870-f5w6fw6q 3816 16 opportunities opportunity NNS cord-006870-f5w6fw6q 3816 17 currently currently RB cord-006870-f5w6fw6q 3816 18 available available JJ cord-006870-f5w6fw6q 3816 19 in in IN cord-006870-f5w6fw6q 3816 20 stroke stroke NN cord-006870-f5w6fw6q 3816 21 genetics genetics NN cord-006870-f5w6fw6q 3816 22 research research NN cord-006870-f5w6fw6q 3816 23 . . . cord-006870-f5w6fw6q 3817 1 The the DT cord-006870-f5w6fw6q 3817 2 International International NNP cord-006870-f5w6fw6q 3817 3 Stroke Stroke NNP cord-006870-f5w6fw6q 3817 4 Genetics Genetics NNP cord-006870-f5w6fw6q 3817 5 Consortium Consortium NNP cord-006870-f5w6fw6q 3817 6 ( ( -LRB- cord-006870-f5w6fw6q 3817 7 ISGC ISGC NNP cord-006870-f5w6fw6q 3817 8 ) ) -RRB- cord-006870-f5w6fw6q 3817 9 has have VBZ cord-006870-f5w6fw6q 3817 10 created create VBN cord-006870-f5w6fw6q 3817 11 the the DT cord-006870-f5w6fw6q 3817 12 Cerebrovascular Cerebrovascular NNP cord-006870-f5w6fw6q 3817 13 Disease Disease NNP cord-006870-f5w6fw6q 3817 14 Knowledge Knowledge NNP cord-006870-f5w6fw6q 3817 15 Portal Portal NNP cord-006870-f5w6fw6q 3817 16 ( ( -LRB- cord-006870-f5w6fw6q 3817 17 CDKP CDKP NNP cord-006870-f5w6fw6q 3817 18 ) ) -RRB- cord-006870-f5w6fw6q 3817 19 , , , cord-006870-f5w6fw6q 3817 20 a a DT cord-006870-f5w6fw6q 3817 21 comprehensive comprehensive JJ cord-006870-f5w6fw6q 3817 22 web web NN cord-006870-f5w6fw6q 3817 23 - - HYPH cord-006870-f5w6fw6q 3817 24 based base VBN cord-006870-f5w6fw6q 3817 25 resource resource NN cord-006870-f5w6fw6q 3817 26 to to TO cord-006870-f5w6fw6q 3817 27 explore explore VB cord-006870-f5w6fw6q 3817 28 and and CC cord-006870-f5w6fw6q 3817 29 freely freely RB cord-006870-f5w6fw6q 3817 30 access access VB cord-006870-f5w6fw6q 3817 31 genetic genetic JJ cord-006870-f5w6fw6q 3817 32 data datum NNS cord-006870-f5w6fw6q 3817 33 related relate VBN cord-006870-f5w6fw6q 3817 34 to to IN cord-006870-f5w6fw6q 3817 35 cerebrovascular cerebrovascular JJ cord-006870-f5w6fw6q 3817 36 diseases disease NNS cord-006870-f5w6fw6q 3817 37 . . . cord-006870-f5w6fw6q 3818 1 Funded fund VBN cord-006870-f5w6fw6q 3818 2 by by IN cord-006870-f5w6fw6q 3818 3 the the DT cord-006870-f5w6fw6q 3818 4 NIH NIH NNP cord-006870-f5w6fw6q 3818 5 , , , cord-006870-f5w6fw6q 3818 6 the the DT cord-006870-f5w6fw6q 3818 7 CDKP CDKP NNP cord-006870-f5w6fw6q 3818 8 has have VBZ cord-006870-f5w6fw6q 3818 9 been be VBN cord-006870-f5w6fw6q 3818 10 jointly jointly RB cord-006870-f5w6fw6q 3818 11 developed develop VBN cord-006870-f5w6fw6q 3818 12 by by IN cord-006870-f5w6fw6q 3818 13 the the DT cord-006870-f5w6fw6q 3818 14 ISGC ISGC NNP cord-006870-f5w6fw6q 3818 15 and and CC cord-006870-f5w6fw6q 3818 16 the the DT cord-006870-f5w6fw6q 3818 17 American American NNP cord-006870-f5w6fw6q 3818 18 Heart Heart NNP cord-006870-f5w6fw6q 3818 19 Association Association NNP cord-006870-f5w6fw6q 3818 20 ( ( -LRB- cord-006870-f5w6fw6q 3818 21 AHA AHA NNP cord-006870-f5w6fw6q 3818 22 ) ) -RRB- cord-006870-f5w6fw6q 3818 23 Institute Institute NNP cord-006870-f5w6fw6q 3818 24 for for IN cord-006870-f5w6fw6q 3818 25 Precision Precision NNP cord-006870-f5w6fw6q 3818 26 Cardiovascular Cardiovascular NNP cord-006870-f5w6fw6q 3818 27 Medicine Medicine NNP cord-006870-f5w6fw6q 3818 28 . . . cord-006870-f5w6fw6q 3819 1 The the DT cord-006870-f5w6fw6q 3819 2 CDKP CDKP NNP cord-006870-f5w6fw6q 3819 3 seeks seek VBZ cord-006870-f5w6fw6q 3819 4 to to TO cord-006870-f5w6fw6q 3819 5 democratize democratize VB cord-006870-f5w6fw6q 3819 6 access access NN cord-006870-f5w6fw6q 3819 7 to to IN cord-006870-f5w6fw6q 3819 8 genomic genomic JJ cord-006870-f5w6fw6q 3819 9 data datum NNS cord-006870-f5w6fw6q 3819 10 and and CC cord-006870-f5w6fw6q 3819 11 potentiate potentiate VB cord-006870-f5w6fw6q 3819 12 stroke stroke NN cord-006870-f5w6fw6q 3819 13 genomics genomic NNS cord-006870-f5w6fw6q 3819 14 research research NN cord-006870-f5w6fw6q 3819 15 by by IN cord-006870-f5w6fw6q 3819 16 providing provide VBG cord-006870-f5w6fw6q 3819 17 open open JJ cord-006870-f5w6fw6q 3819 18 access access NN cord-006870-f5w6fw6q 3819 19 to to IN cord-006870-f5w6fw6q 3819 20 genetic genetic JJ cord-006870-f5w6fw6q 3819 21 , , , cord-006870-f5w6fw6q 3819 22 phenotypic phenotypic JJ cord-006870-f5w6fw6q 3819 23 and and CC cord-006870-f5w6fw6q 3819 24 imaging image VBG cord-006870-f5w6fw6q 3819 25 data datum NNS cord-006870-f5w6fw6q 3819 26 on on IN cord-006870-f5w6fw6q 3819 27 stroke stroke NN cord-006870-f5w6fw6q 3819 28 . . . cord-006870-f5w6fw6q 3820 1 Within within IN cord-006870-f5w6fw6q 3820 2 the the DT cord-006870-f5w6fw6q 3820 3 CDKP CDKP NNP cord-006870-f5w6fw6q 3820 4 , , , cord-006870-f5w6fw6q 3820 5 data datum NNS cord-006870-f5w6fw6q 3820 6 are be VBP cord-006870-f5w6fw6q 3820 7 aggregated aggregate VBN cord-006870-f5w6fw6q 3820 8 , , , cord-006870-f5w6fw6q 3820 9 integrated integrate VBN cord-006870-f5w6fw6q 3820 10 , , , cord-006870-f5w6fw6q 3820 11 and and CC cord-006870-f5w6fw6q 3820 12 harmonized harmonize VBD cord-006870-f5w6fw6q 3820 13 according accord VBG cord-006870-f5w6fw6q 3820 14 to to IN cord-006870-f5w6fw6q 3820 15 a a DT cord-006870-f5w6fw6q 3820 16 pre pre JJ cord-006870-f5w6fw6q 3820 17 - - JJ cord-006870-f5w6fw6q 3820 18 specified specified JJ cord-006870-f5w6fw6q 3820 19 standardized standardized JJ cord-006870-f5w6fw6q 3820 20 pipeline pipeline NN cord-006870-f5w6fw6q 3820 21 . . . cord-006870-f5w6fw6q 3821 1 Any any DT cord-006870-f5w6fw6q 3821 2 institution institution NN cord-006870-f5w6fw6q 3821 3 or or CC cord-006870-f5w6fw6q 3821 4 investigator investigator NN cord-006870-f5w6fw6q 3821 5 working work VBG cord-006870-f5w6fw6q 3821 6 with with IN cord-006870-f5w6fw6q 3821 7 stroke stroke NN cord-006870-f5w6fw6q 3821 8 genomic genomic JJ cord-006870-f5w6fw6q 3821 9 data datum NNS cord-006870-f5w6fw6q 3821 10 is be VBZ cord-006870-f5w6fw6q 3821 11 welcome welcome JJ cord-006870-f5w6fw6q 3821 12 to to TO cord-006870-f5w6fw6q 3821 13 deposit deposit VB cord-006870-f5w6fw6q 3821 14 their -PRON- PRP$ cord-006870-f5w6fw6q 3821 15 data datum NNS cord-006870-f5w6fw6q 3821 16 or or CC cord-006870-f5w6fw6q 3821 17 use use VB cord-006870-f5w6fw6q 3821 18 available available JJ cord-006870-f5w6fw6q 3821 19 data datum NNS cord-006870-f5w6fw6q 3821 20 . . . cord-006870-f5w6fw6q 3822 1 The the DT cord-006870-f5w6fw6q 3822 2 CDKP CDKP NNP cord-006870-f5w6fw6q 3822 3 houses house VBZ cord-006870-f5w6fw6q 3822 4 two two CD cord-006870-f5w6fw6q 3822 5 types type NNS cord-006870-f5w6fw6q 3822 6 of of IN cord-006870-f5w6fw6q 3822 7 data datum NNS cord-006870-f5w6fw6q 3822 8 , , , cord-006870-f5w6fw6q 3822 9 each each DT cord-006870-f5w6fw6q 3822 10 meeting meet VBG cord-006870-f5w6fw6q 3822 11 different different JJ cord-006870-f5w6fw6q 3822 12 regulatory regulatory JJ cord-006870-f5w6fw6q 3822 13 and and CC cord-006870-f5w6fw6q 3822 14 analytical analytical JJ cord-006870-f5w6fw6q 3822 15 needs need NNS cord-006870-f5w6fw6q 3822 16 : : : cord-006870-f5w6fw6q 3822 17 summary summary NN cord-006870-f5w6fw6q 3822 18 level level NN cord-006870-f5w6fw6q 3822 19 data datum NNS cord-006870-f5w6fw6q 3822 20 and and CC cord-006870-f5w6fw6q 3822 21 individual individual JJ cord-006870-f5w6fw6q 3822 22 level level NN cord-006870-f5w6fw6q 3822 23 data datum NNS cord-006870-f5w6fw6q 3822 24 . . . cord-006870-f5w6fw6q 3823 1 The the DT cord-006870-f5w6fw6q 3823 2 CDKP CDKP NNP cord-006870-f5w6fw6q 3823 3 offers offer VBZ cord-006870-f5w6fw6q 3823 4 three three CD cord-006870-f5w6fw6q 3823 5 main main JJ cord-006870-f5w6fw6q 3823 6 features feature NNS cord-006870-f5w6fw6q 3823 7 : : : cord-006870-f5w6fw6q 3823 8 ( ( -LRB- cord-006870-f5w6fw6q 3823 9 1 1 LS cord-006870-f5w6fw6q 3823 10 ) ) -RRB- cord-006870-f5w6fw6q 3823 11 a a DT cord-006870-f5w6fw6q 3823 12 web web NN cord-006870-f5w6fw6q 3823 13 - - HYPH cord-006870-f5w6fw6q 3823 14 based base VBN cord-006870-f5w6fw6q 3823 15 graphical graphical JJ cord-006870-f5w6fw6q 3823 16 user user NN cord-006870-f5w6fw6q 3823 17 interphase interphase NN cord-006870-f5w6fw6q 3823 18 that that WDT cord-006870-f5w6fw6q 3823 19 allows allow VBZ cord-006870-f5w6fw6q 3823 20 the the DT cord-006870-f5w6fw6q 3823 21 exploration exploration NN cord-006870-f5w6fw6q 3823 22 of of IN cord-006870-f5w6fw6q 3823 23 stroke stroke NN cord-006870-f5w6fw6q 3823 24 genomics genomic NNS cord-006870-f5w6fw6q 3823 25 information information NN cord-006870-f5w6fw6q 3823 26 through through IN cord-006870-f5w6fw6q 3823 27 a a DT cord-006870-f5w6fw6q 3823 28 wide wide JJ cord-006870-f5w6fw6q 3823 29 menu menu NN cord-006870-f5w6fw6q 3823 30 of of IN cord-006870-f5w6fw6q 3823 31 integrated integrated JJ cord-006870-f5w6fw6q 3823 32 tools tool NNS cord-006870-f5w6fw6q 3823 33 for for IN cord-006870-f5w6fw6q 3823 34 analysis analysis NN cord-006870-f5w6fw6q 3823 35 and and CC cord-006870-f5w6fw6q 3823 36 data datum NNS cord-006870-f5w6fw6q 3823 37 visualization visualization NN cord-006870-f5w6fw6q 3823 38 ; ; : cord-006870-f5w6fw6q 3823 39 ( ( -LRB- cord-006870-f5w6fw6q 3823 40 2 2 LS cord-006870-f5w6fw6q 3823 41 ) ) -RRB- cord-006870-f5w6fw6q 3823 42 a a DT cord-006870-f5w6fw6q 3823 43 repository repository NN cord-006870-f5w6fw6q 3823 44 of of IN cord-006870-f5w6fw6q 3823 45 full full JJ cord-006870-f5w6fw6q 3823 46 sets set NNS cord-006870-f5w6fw6q 3823 47 of of IN cord-006870-f5w6fw6q 3823 48 genome genome NN cord-006870-f5w6fw6q 3823 49 - - HYPH cord-006870-f5w6fw6q 3823 50 wide wide JJ cord-006870-f5w6fw6q 3823 51 summary summary NN cord-006870-f5w6fw6q 3823 52 statistics statistic NNS cord-006870-f5w6fw6q 3823 53 produced produce VBN cord-006870-f5w6fw6q 3823 54 by by IN cord-006870-f5w6fw6q 3823 55 published publish VBN cord-006870-f5w6fw6q 3823 56 landmark landmark NN cord-006870-f5w6fw6q 3823 57 studies study NNS cord-006870-f5w6fw6q 3823 58 in in IN cord-006870-f5w6fw6q 3823 59 the the DT cord-006870-f5w6fw6q 3823 60 field field NN cord-006870-f5w6fw6q 3823 61 , , , cord-006870-f5w6fw6q 3823 62 available available JJ cord-006870-f5w6fw6q 3823 63 with with IN cord-006870-f5w6fw6q 3823 64 a a DT cord-006870-f5w6fw6q 3823 65 single single JJ cord-006870-f5w6fw6q 3823 66 mouse mouse NN cord-006870-f5w6fw6q 3823 67 click click NN cord-006870-f5w6fw6q 3823 68 ; ; , cord-006870-f5w6fw6q 3823 69 and and CC cord-006870-f5w6fw6q 3823 70 ( ( -LRB- cord-006870-f5w6fw6q 3823 71 3 3 LS cord-006870-f5w6fw6q 3823 72 ) ) -RRB- cord-006870-f5w6fw6q 3823 73 a a DT cord-006870-f5w6fw6q 3823 74 repository repository NN cord-006870-f5w6fw6q 3823 75 of of IN cord-006870-f5w6fw6q 3823 76 individual individual JJ cord-006870-f5w6fw6q 3823 77 level level NN cord-006870-f5w6fw6q 3823 78 data datum NNS cord-006870-f5w6fw6q 3823 79 , , , cord-006870-f5w6fw6q 3823 80 accessible accessible JJ cord-006870-f5w6fw6q 3823 81 through through IN cord-006870-f5w6fw6q 3823 82 a a DT cord-006870-f5w6fw6q 3823 83 secure secure JJ cord-006870-f5w6fw6q 3823 84 cloud cloud NN cord-006870-f5w6fw6q 3823 85 working work VBG cord-006870-f5w6fw6q 3823 86 space space NN cord-006870-f5w6fw6q 3823 87 provided provide VBN cord-006870-f5w6fw6q 3823 88 by by IN cord-006870-f5w6fw6q 3823 89 the the DT cord-006870-f5w6fw6q 3823 90 AHA AHA NNP cord-006870-f5w6fw6q 3823 91 Platform Platform NNP cord-006870-f5w6fw6q 3823 92 for for IN cord-006870-f5w6fw6q 3823 93 Precision Precision NNP cord-006870-f5w6fw6q 3823 94 Medicine Medicine NNP cord-006870-f5w6fw6q 3823 95 . . . cord-006870-f5w6fw6q 3824 1 The the DT cord-006870-f5w6fw6q 3824 2 CDKP CDKP NNP cord-006870-f5w6fw6q 3824 3 can can MD cord-006870-f5w6fw6q 3824 4 be be VB cord-006870-f5w6fw6q 3824 5 accessed access VBN cord-006870-f5w6fw6q 3824 6 at at IN cord-006870-f5w6fw6q 3824 7 www.cerebrovascularportal.org www.cerebrovascularportal.org NN cord-006870-f5w6fw6q 3824 8 . . . cord-006870-f5w6fw6q 3825 1 The the DT cord-006870-f5w6fw6q 3825 2 CDKP CDKP NNP cord-006870-f5w6fw6q 3825 3 advances advance VBZ cord-006870-f5w6fw6q 3825 4 the the DT cord-006870-f5w6fw6q 3825 5 ISGC ISGC NNP cord-006870-f5w6fw6q 3825 6 's 's POS cord-006870-f5w6fw6q 3825 7 goal goal NN cord-006870-f5w6fw6q 3825 8 of of IN cord-006870-f5w6fw6q 3825 9 liberal liberal JJ cord-006870-f5w6fw6q 3825 10 data datum NNS cord-006870-f5w6fw6q 3825 11 sharing sharing NN cord-006870-f5w6fw6q 3825 12 in in IN cord-006870-f5w6fw6q 3825 13 stroke stroke NN cord-006870-f5w6fw6q 3825 14 genomics genomic NNS cord-006870-f5w6fw6q 3825 15 and and CC cord-006870-f5w6fw6q 3825 16 other other JJ cord-006870-f5w6fw6q 3825 17 areas area NNS cord-006870-f5w6fw6q 3825 18 of of IN cord-006870-f5w6fw6q 3825 19 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 3825 20 research research NN cord-006870-f5w6fw6q 3825 21 that that WDT cord-006870-f5w6fw6q 3825 22 may may MD cord-006870-f5w6fw6q 3825 23 benefit benefit VB cord-006870-f5w6fw6q 3825 24 from from IN cord-006870-f5w6fw6q 3825 25 genomic genomic JJ cord-006870-f5w6fw6q 3825 26 analyses analysis NNS cord-006870-f5w6fw6q 3825 27 . . . cord-006870-f5w6fw6q 3826 1 In in IN cord-006870-f5w6fw6q 3826 2 the the DT cord-006870-f5w6fw6q 3826 3 future future NN cord-006870-f5w6fw6q 3826 4 , , , cord-006870-f5w6fw6q 3826 5 phenotypic phenotypic JJ cord-006870-f5w6fw6q 3826 6 datasets dataset NNS cord-006870-f5w6fw6q 3826 7 can can MD cord-006870-f5w6fw6q 3826 8 be be VB cord-006870-f5w6fw6q 3826 9 added add VBN cord-006870-f5w6fw6q 3826 10 to to TO cord-006870-f5w6fw6q 3826 11 further further RB cord-006870-f5w6fw6q 3826 12 enrich enrich VB cord-006870-f5w6fw6q 3826 13 sharing sharing NN cord-006870-f5w6fw6q 3826 14 of of IN cord-006870-f5w6fw6q 3826 15 non non JJ cord-006870-f5w6fw6q 3826 16 - - JJ cord-006870-f5w6fw6q 3826 17 genetic genetic JJ cord-006870-f5w6fw6q 3826 18 data datum NNS cord-006870-f5w6fw6q 3826 19 as as RB cord-006870-f5w6fw6q 3826 20 well well RB cord-006870-f5w6fw6q 3826 21 . . . cord-006870-f5w6fw6q 3827 1 Hyperosmolar Hyperosmolar NNP cord-006870-f5w6fw6q 3827 2 therapy therapy NN cord-006870-f5w6fw6q 3827 3 using use VBG cord-006870-f5w6fw6q 3827 4 hypertonic hypertonic JJ cord-006870-f5w6fw6q 3827 5 saline saline NN cord-006870-f5w6fw6q 3827 6 is be VBZ cord-006870-f5w6fw6q 3827 7 common common JJ cord-006870-f5w6fw6q 3827 8 in in IN cord-006870-f5w6fw6q 3827 9 patients patient NNS cord-006870-f5w6fw6q 3827 10 admitted admit VBN cord-006870-f5w6fw6q 3827 11 to to IN cord-006870-f5w6fw6q 3827 12 the the DT cord-006870-f5w6fw6q 3827 13 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 3827 14 Care Care NNP cord-006870-f5w6fw6q 3827 15 Unit Unit NNP cord-006870-f5w6fw6q 3827 16 ( ( -LRB- cord-006870-f5w6fw6q 3827 17 NCCU NCCU NNP cord-006870-f5w6fw6q 3827 18 ) ) -RRB- cord-006870-f5w6fw6q 3827 19 for for IN cord-006870-f5w6fw6q 3827 20 the the DT cord-006870-f5w6fw6q 3827 21 management management NN cord-006870-f5w6fw6q 3827 22 of of IN cord-006870-f5w6fw6q 3827 23 different different JJ cord-006870-f5w6fw6q 3827 24 type type NN cord-006870-f5w6fw6q 3827 25 of of IN cord-006870-f5w6fw6q 3827 26 cytogenic cytogenic JJ cord-006870-f5w6fw6q 3827 27 cerebral cerebral JJ cord-006870-f5w6fw6q 3827 28 edema edema NN cord-006870-f5w6fw6q 3827 29 or or CC cord-006870-f5w6fw6q 3827 30 increased increase VBN cord-006870-f5w6fw6q 3827 31 intracranial intracranial JJ cord-006870-f5w6fw6q 3827 32 pressure pressure NN cord-006870-f5w6fw6q 3827 33 ( ( -LRB- cord-006870-f5w6fw6q 3827 34 ICP ICP NNP cord-006870-f5w6fw6q 3827 35 ) ) -RRB- cord-006870-f5w6fw6q 3827 36 . . . cord-006870-f5w6fw6q 3828 1 Vancomycin Vancomycin NNP cord-006870-f5w6fw6q 3828 2 is be VBZ cord-006870-f5w6fw6q 3828 3 commonly commonly RB cord-006870-f5w6fw6q 3828 4 prescribed prescribe VBN cord-006870-f5w6fw6q 3828 5 in in IN cord-006870-f5w6fw6q 3828 6 NCCU NCCU NNP cord-006870-f5w6fw6q 3828 7 as as IN cord-006870-f5w6fw6q 3828 8 empiric empiric JJ cord-006870-f5w6fw6q 3828 9 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 3828 10 therapy therapy NN cord-006870-f5w6fw6q 3828 11 . . . cord-006870-f5w6fw6q 3829 1 The the DT cord-006870-f5w6fw6q 3829 2 purpose purpose NN cord-006870-f5w6fw6q 3829 3 of of IN cord-006870-f5w6fw6q 3829 4 the the DT cord-006870-f5w6fw6q 3829 5 study study NN cord-006870-f5w6fw6q 3829 6 is be VBZ cord-006870-f5w6fw6q 3829 7 to to TO cord-006870-f5w6fw6q 3829 8 evaluate evaluate VB cord-006870-f5w6fw6q 3829 9 the the DT cord-006870-f5w6fw6q 3829 10 effects effect NNS cord-006870-f5w6fw6q 3829 11 of of IN cord-006870-f5w6fw6q 3829 12 hypertonic hypertonic JJ cord-006870-f5w6fw6q 3829 13 saline saline NN cord-006870-f5w6fw6q 3829 14 therapy therapy NN cord-006870-f5w6fw6q 3829 15 on on IN cord-006870-f5w6fw6q 3829 16 the the DT cord-006870-f5w6fw6q 3829 17 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 3829 18 parameters parameter NNS cord-006870-f5w6fw6q 3829 19 of of IN cord-006870-f5w6fw6q 3829 20 vancomycin vancomycin NN cord-006870-f5w6fw6q 3829 21 in in IN cord-006870-f5w6fw6q 3829 22 critically critically RB cord-006870-f5w6fw6q 3829 23 ill ill JJ cord-006870-f5w6fw6q 3829 24 patients patient NNS cord-006870-f5w6fw6q 3829 25 with with IN cord-006870-f5w6fw6q 3829 26 generalized generalized JJ cord-006870-f5w6fw6q 3829 27 or or CC cord-006870-f5w6fw6q 3829 28 compartmental compartmental JJ cord-006870-f5w6fw6q 3829 29 ICP ICP NNP cord-006870-f5w6fw6q 3829 30 . . . cord-006870-f5w6fw6q 3830 1 This this DT cord-006870-f5w6fw6q 3830 2 was be VBD cord-006870-f5w6fw6q 3830 3 a a DT cord-006870-f5w6fw6q 3830 4 retrospective retrospective JJ cord-006870-f5w6fw6q 3830 5 , , , cord-006870-f5w6fw6q 3830 6 observational observational JJ cord-006870-f5w6fw6q 3830 7 study study NN cord-006870-f5w6fw6q 3830 8 of of IN cord-006870-f5w6fw6q 3830 9 adult adult NN cord-006870-f5w6fw6q 3830 10 patient patient NN cord-006870-f5w6fw6q 3830 11 consecutively consecutively RB cord-006870-f5w6fw6q 3830 12 admitted admit VBN cord-006870-f5w6fw6q 3830 13 in in IN cord-006870-f5w6fw6q 3830 14 the the DT cord-006870-f5w6fw6q 3830 15 NCCU NCCU NNP cord-006870-f5w6fw6q 3830 16 between between IN cord-006870-f5w6fw6q 3830 17 February February NNP cord-006870-f5w6fw6q 3830 18 2012 2012 CD cord-006870-f5w6fw6q 3830 19 and and CC cord-006870-f5w6fw6q 3830 20 February February NNP cord-006870-f5w6fw6q 3830 21 2017 2017 CD cord-006870-f5w6fw6q 3830 22 who who WP cord-006870-f5w6fw6q 3830 23 received receive VBD cord-006870-f5w6fw6q 3830 24 hypertonic hypertonic JJ cord-006870-f5w6fw6q 3830 25 saline saline NN cord-006870-f5w6fw6q 3830 26 ( ( -LRB- cord-006870-f5w6fw6q 3830 27 3 3 CD cord-006870-f5w6fw6q 3830 28 % % NN cord-006870-f5w6fw6q 3830 29 sodium sodium NN cord-006870-f5w6fw6q 3830 30 chloride chloride NN cord-006870-f5w6fw6q 3830 31 ) ) -RRB- cord-006870-f5w6fw6q 3830 32 and and CC cord-006870-f5w6fw6q 3830 33 vancomycin vancomycin NN cord-006870-f5w6fw6q 3830 34 dosing dosing NN cord-006870-f5w6fw6q 3830 35 protocol protocol NN cord-006870-f5w6fw6q 3830 36 managed manage VBN cord-006870-f5w6fw6q 3830 37 by by IN cord-006870-f5w6fw6q 3830 38 the the DT cord-006870-f5w6fw6q 3830 39 pharmacist pharmacist NN cord-006870-f5w6fw6q 3830 40 . . . cord-006870-f5w6fw6q 3831 1 Patients patient NNS cord-006870-f5w6fw6q 3831 2 with with IN cord-006870-f5w6fw6q 3831 3 serum serum NN cord-006870-f5w6fw6q 3831 4 creatinine creatinine NN cord-006870-f5w6fw6q 3831 5 > > XX cord-006870-f5w6fw6q 3831 6 1.4 1.4 CD cord-006870-f5w6fw6q 3831 7 mg mg NNP cord-006870-f5w6fw6q 3831 8 / / SYM cord-006870-f5w6fw6q 3831 9 dL dL NNP cord-006870-f5w6fw6q 3831 10 were be VBD cord-006870-f5w6fw6q 3831 11 excluded exclude VBN cord-006870-f5w6fw6q 3831 12 from from IN cord-006870-f5w6fw6q 3831 13 the the DT cord-006870-f5w6fw6q 3831 14 study study NN cord-006870-f5w6fw6q 3831 15 . . . cord-006870-f5w6fw6q 3832 1 The the DT cord-006870-f5w6fw6q 3832 2 estimation estimation NN cord-006870-f5w6fw6q 3832 3 of of IN cord-006870-f5w6fw6q 3832 4 vancomycin vancomycin NN cord-006870-f5w6fw6q 3832 5 trough trough NN cord-006870-f5w6fw6q 3832 6 levels level NNS cord-006870-f5w6fw6q 3832 7 was be VBD cord-006870-f5w6fw6q 3832 8 done do VBN cord-006870-f5w6fw6q 3832 9 by by IN cord-006870-f5w6fw6q 3832 10 using use VBG cord-006870-f5w6fw6q 3832 11 published publish VBN cord-006870-f5w6fw6q 3832 12 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 3832 13 equations equation NNS cord-006870-f5w6fw6q 3832 14 and and CC cord-006870-f5w6fw6q 3832 15 then then RB cord-006870-f5w6fw6q 3832 16 compared compare VBN cord-006870-f5w6fw6q 3832 17 to to IN cord-006870-f5w6fw6q 3832 18 the the DT cord-006870-f5w6fw6q 3832 19 measured measure VBN cord-006870-f5w6fw6q 3832 20 trough trough NN cord-006870-f5w6fw6q 3832 21 levels level NNS cord-006870-f5w6fw6q 3832 22 with with IN cord-006870-f5w6fw6q 3832 23 the the DT cord-006870-f5w6fw6q 3832 24 Paired Paired NNP cord-006870-f5w6fw6q 3832 25 t t NN cord-006870-f5w6fw6q 3832 26 test test NN cord-006870-f5w6fw6q 3832 27 . . . cord-006870-f5w6fw6q 3833 1 The the DT cord-006870-f5w6fw6q 3833 2 study study NN cord-006870-f5w6fw6q 3833 3 protocol protocol NN cord-006870-f5w6fw6q 3833 4 was be VBD cord-006870-f5w6fw6q 3833 5 approved approve VBN cord-006870-f5w6fw6q 3833 6 by by IN cord-006870-f5w6fw6q 3833 7 our -PRON- PRP$ cord-006870-f5w6fw6q 3833 8 Institutional Institutional NNP cord-006870-f5w6fw6q 3833 9 Review Review NNP cord-006870-f5w6fw6q 3833 10 Board Board NNP cord-006870-f5w6fw6q 3833 11 . . . cord-006870-f5w6fw6q 3834 1 Of of IN cord-006870-f5w6fw6q 3834 2 forty forty CD cord-006870-f5w6fw6q 3834 3 - - HYPH cord-006870-f5w6fw6q 3834 4 four four CD cord-006870-f5w6fw6q 3834 5 patients patient NNS cord-006870-f5w6fw6q 3834 6 who who WP cord-006870-f5w6fw6q 3834 7 met meet VBD cord-006870-f5w6fw6q 3834 8 the the DT cord-006870-f5w6fw6q 3834 9 inclusion inclusion NN cord-006870-f5w6fw6q 3834 10 criteria criterion NNS cord-006870-f5w6fw6q 3834 11 , , , cord-006870-f5w6fw6q 3834 12 twenty twenty CD cord-006870-f5w6fw6q 3834 13 - - HYPH cord-006870-f5w6fw6q 3834 14 one one CD cord-006870-f5w6fw6q 3834 15 patients patient NNS cord-006870-f5w6fw6q 3834 16 ( ( -LRB- cord-006870-f5w6fw6q 3834 17 47.7 47.7 CD cord-006870-f5w6fw6q 3834 18 % % NN cord-006870-f5w6fw6q 3834 19 ) ) -RRB- cord-006870-f5w6fw6q 3834 20 were be VBD cord-006870-f5w6fw6q 3834 21 diagnosed diagnose VBN cord-006870-f5w6fw6q 3834 22 with with IN cord-006870-f5w6fw6q 3834 23 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3834 24 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3834 25 , , , cord-006870-f5w6fw6q 3834 26 nine nine CD cord-006870-f5w6fw6q 3834 27 ( ( -LRB- cord-006870-f5w6fw6q 3834 28 20.5 20.5 CD cord-006870-f5w6fw6q 3834 29 % % NN cord-006870-f5w6fw6q 3834 30 ) ) -RRB- cord-006870-f5w6fw6q 3835 1 ischemic ischemic JJ cord-006870-f5w6fw6q 3835 2 stroke stroke NN cord-006870-f5w6fw6q 3835 3 , , , cord-006870-f5w6fw6q 3835 4 seven seven CD cord-006870-f5w6fw6q 3835 5 ( ( -LRB- cord-006870-f5w6fw6q 3835 6 15.5 15.5 CD cord-006870-f5w6fw6q 3835 7 % % NN cord-006870-f5w6fw6q 3835 8 ) ) -RRB- cord-006870-f5w6fw6q 3836 1 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 3836 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3836 3 , , , cord-006870-f5w6fw6q 3836 4 four four CD cord-006870-f5w6fw6q 3836 5 ( ( -LRB- cord-006870-f5w6fw6q 3836 6 9 9 CD cord-006870-f5w6fw6q 3836 7 % % NN cord-006870-f5w6fw6q 3836 8 ) ) -RRB- cord-006870-f5w6fw6q 3836 9 subdural subdural JJ cord-006870-f5w6fw6q 3836 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3836 11 , , , cord-006870-f5w6fw6q 3836 12 two two CD cord-006870-f5w6fw6q 3836 13 with with IN cord-006870-f5w6fw6q 3836 14 brain brain NN cord-006870-f5w6fw6q 3836 15 tumors tumor NNS cord-006870-f5w6fw6q 3836 16 , , , cord-006870-f5w6fw6q 3836 17 and and CC cord-006870-f5w6fw6q 3836 18 one one CD cord-006870-f5w6fw6q 3836 19 patient patient NN cord-006870-f5w6fw6q 3836 20 with with IN cord-006870-f5w6fw6q 3836 21 chiari chiari FW cord-006870-f5w6fw6q 3836 22 malformation malformation NN cord-006870-f5w6fw6q 3836 23 . . . cord-006870-f5w6fw6q 3837 1 The the DT cord-006870-f5w6fw6q 3837 2 mean mean JJ cord-006870-f5w6fw6q 3837 3 dosing dose VBG cord-006870-f5w6fw6q 3837 4 regimen regimen NN cord-006870-f5w6fw6q 3837 5 was be VBD cord-006870-f5w6fw6q 3837 6 13.8 13.8 CD cord-006870-f5w6fw6q 3837 7 ± ± NNP cord-006870-f5w6fw6q 3837 8 3.4 3.4 CD cord-006870-f5w6fw6q 3837 9 mg mg NNP cord-006870-f5w6fw6q 3837 10 / / SYM cord-006870-f5w6fw6q 3837 11 kg kg NNP cord-006870-f5w6fw6q 3837 12 every every DT cord-006870-f5w6fw6q 3837 13 12 12 CD cord-006870-f5w6fw6q 3837 14 ( ( -LRB- cord-006870-f5w6fw6q 3837 15 8 8 CD cord-006870-f5w6fw6q 3837 16 -24 -24 NN cord-006870-f5w6fw6q 3837 17 ) ) -RRB- cord-006870-f5w6fw6q 3837 18 h. h. NN cord-006870-f5w6fw6q 3838 1 The the DT cord-006870-f5w6fw6q 3838 2 mean mean NN cord-006870-f5w6fw6q 3838 3 measured measure VBN cord-006870-f5w6fw6q 3838 4 trough trough NN cord-006870-f5w6fw6q 3838 5 level level NN cord-006870-f5w6fw6q 3838 6 was be VBD cord-006870-f5w6fw6q 3838 7 lower low JJR cord-006870-f5w6fw6q 3838 8 than than IN cord-006870-f5w6fw6q 3838 9 the the DT cord-006870-f5w6fw6q 3838 10 predicted predict VBN cord-006870-f5w6fw6q 3838 11 trough trough NN cord-006870-f5w6fw6q 3838 12 level level NN cord-006870-f5w6fw6q 3838 13 ( ( -LRB- cord-006870-f5w6fw6q 3838 14 9 9 CD cord-006870-f5w6fw6q 3838 15 ± ± NNP cord-006870-f5w6fw6q 3838 16 3.3 3.3 CD cord-006870-f5w6fw6q 3838 17 vs. vs. NN cord-006870-f5w6fw6q 3838 18 18.9 18.9 CD cord-006870-f5w6fw6q 3838 19 ± ± CD cord-006870-f5w6fw6q 3838 20 6.2 6.2 CD cord-006870-f5w6fw6q 3838 21 mcg mcg NN cord-006870-f5w6fw6q 3838 22 / / SYM cord-006870-f5w6fw6q 3838 23 mL ml NN cord-006870-f5w6fw6q 3838 24 ; ; : cord-006870-f5w6fw6q 3838 25 p p NN cord-006870-f5w6fw6q 3838 26 < < XX cord-006870-f5w6fw6q 3838 27 0.0001 0.0001 CD cord-006870-f5w6fw6q 3838 28 ) ) -RRB- cord-006870-f5w6fw6q 3838 29 . . . cord-006870-f5w6fw6q 3839 1 The the DT cord-006870-f5w6fw6q 3839 2 mean mean JJ cord-006870-f5w6fw6q 3839 3 serum serum NN cord-006870-f5w6fw6q 3839 4 sodium sodium NN cord-006870-f5w6fw6q 3839 5 level level NN cord-006870-f5w6fw6q 3839 6 was be VBD cord-006870-f5w6fw6q 3839 7 147 147 CD cord-006870-f5w6fw6q 3839 8 ± ± XX cord-006870-f5w6fw6q 3840 1 8 8 CD cord-006870-f5w6fw6q 3840 2 mEq mEq NNS cord-006870-f5w6fw6q 3840 3 / / SYM cord-006870-f5w6fw6q 3840 4 L L NNP cord-006870-f5w6fw6q 3840 5 and and CC cord-006870-f5w6fw6q 3840 6 the the DT cord-006870-f5w6fw6q 3840 7 mean mean JJ cord-006870-f5w6fw6q 3840 8 serum serum NN cord-006870-f5w6fw6q 3840 9 osmolality osmolality NN cord-006870-f5w6fw6q 3840 10 was be VBD cord-006870-f5w6fw6q 3840 11 317 317 CD cord-006870-f5w6fw6q 3840 12 ± ± NNP cord-006870-f5w6fw6q 3840 13 18 18 CD cord-006870-f5w6fw6q 3840 14 mOsm mOsm NNP cord-006870-f5w6fw6q 3840 15 / / SYM cord-006870-f5w6fw6q 3840 16 kg kg NN cord-006870-f5w6fw6q 3840 17 . . . cord-006870-f5w6fw6q 3841 1 Critically critically RB cord-006870-f5w6fw6q 3841 2 ill ill JJ cord-006870-f5w6fw6q 3841 3 patients patient NNS cord-006870-f5w6fw6q 3841 4 with with IN cord-006870-f5w6fw6q 3841 5 cerebral cerebral JJ cord-006870-f5w6fw6q 3841 6 edema edema NN cord-006870-f5w6fw6q 3841 7 or or CC cord-006870-f5w6fw6q 3841 8 high high JJ cord-006870-f5w6fw6q 3841 9 ICP ICP NNP cord-006870-f5w6fw6q 3841 10 who who WP cord-006870-f5w6fw6q 3841 11 were be VBD cord-006870-f5w6fw6q 3841 12 treated treat VBN cord-006870-f5w6fw6q 3841 13 with with IN cord-006870-f5w6fw6q 3841 14 hypertonic hypertonic JJ cord-006870-f5w6fw6q 3841 15 saline saline NN cord-006870-f5w6fw6q 3841 16 achieved achieve VBD cord-006870-f5w6fw6q 3841 17 a a DT cord-006870-f5w6fw6q 3841 18 subtherapeutic subtherapeutic JJ cord-006870-f5w6fw6q 3841 19 vancomycin vancomycin NN cord-006870-f5w6fw6q 3841 20 level level NN cord-006870-f5w6fw6q 3841 21 that that WDT cord-006870-f5w6fw6q 3841 22 may may MD cord-006870-f5w6fw6q 3841 23 lead lead VB cord-006870-f5w6fw6q 3841 24 to to TO cord-006870-f5w6fw6q 3841 25 lower lower VB cord-006870-f5w6fw6q 3841 26 through through IN cord-006870-f5w6fw6q 3841 27 level level NN cord-006870-f5w6fw6q 3841 28 and and CC cord-006870-f5w6fw6q 3841 29 possibly possibly RB cord-006870-f5w6fw6q 3841 30 poor poor JJ cord-006870-f5w6fw6q 3841 31 clinical clinical JJ cord-006870-f5w6fw6q 3841 32 response response NN cord-006870-f5w6fw6q 3841 33 . . . cord-006870-f5w6fw6q 3842 1 Further further JJ cord-006870-f5w6fw6q 3842 2 research research NN cord-006870-f5w6fw6q 3842 3 is be VBZ cord-006870-f5w6fw6q 3842 4 warranted warrant VBN cord-006870-f5w6fw6q 3842 5 to to TO cord-006870-f5w6fw6q 3842 6 evaluate evaluate VB cord-006870-f5w6fw6q 3842 7 the the DT cord-006870-f5w6fw6q 3842 8 clinical clinical JJ cord-006870-f5w6fw6q 3842 9 response response NN cord-006870-f5w6fw6q 3842 10 of of IN cord-006870-f5w6fw6q 3842 11 vancomycin vancomycin NN cord-006870-f5w6fw6q 3842 12 in in IN cord-006870-f5w6fw6q 3842 13 this this DT cord-006870-f5w6fw6q 3842 14 patient patient JJ cord-006870-f5w6fw6q 3842 15 population population NN cord-006870-f5w6fw6q 3842 16 . . . cord-006870-f5w6fw6q 3843 1 Unnecessary unnecessary JJ cord-006870-f5w6fw6q 3843 2 telestroke telestroke NNP cord-006870-f5w6fw6q 3843 3 activations activation NNS cord-006870-f5w6fw6q 3843 4 are be VBP cord-006870-f5w6fw6q 3843 5 costly costly JJ cord-006870-f5w6fw6q 3843 6 to to IN cord-006870-f5w6fw6q 3843 7 emergency emergency NN cord-006870-f5w6fw6q 3843 8 departments department NNS cord-006870-f5w6fw6q 3843 9 ( ( -LRB- cord-006870-f5w6fw6q 3843 10 ED ED NNP cord-006870-f5w6fw6q 3843 11 ) ) -RRB- cord-006870-f5w6fw6q 3843 12 , , , cord-006870-f5w6fw6q 3843 13 telestroke telestroke NNP cord-006870-f5w6fw6q 3843 14 providers provider NNS cord-006870-f5w6fw6q 3843 15 , , , cord-006870-f5w6fw6q 3843 16 and and CC cord-006870-f5w6fw6q 3843 17 patients patient NNS cord-006870-f5w6fw6q 3843 18 . . . cord-006870-f5w6fw6q 3844 1 Therefore therefore RB cord-006870-f5w6fw6q 3844 2 it -PRON- PRP cord-006870-f5w6fw6q 3844 3 is be VBZ cord-006870-f5w6fw6q 3844 4 important important JJ cord-006870-f5w6fw6q 3844 5 that that IN cord-006870-f5w6fw6q 3844 6 ED ED NNP cord-006870-f5w6fw6q 3844 7 nurses nurse NNS cord-006870-f5w6fw6q 3844 8 are be VBP cord-006870-f5w6fw6q 3844 9 well well RB cord-006870-f5w6fw6q 3844 10 trained train VBN cord-006870-f5w6fw6q 3844 11 to to TO cord-006870-f5w6fw6q 3844 12 effectively effectively RB cord-006870-f5w6fw6q 3844 13 recognize recognize VB cord-006870-f5w6fw6q 3844 14 stroke stroke NN cord-006870-f5w6fw6q 3844 15 symptoms symptom NNS cord-006870-f5w6fw6q 3844 16 , , , cord-006870-f5w6fw6q 3844 17 and and CC cord-006870-f5w6fw6q 3844 18 decrease decrease VB cord-006870-f5w6fw6q 3844 19 the the DT cord-006870-f5w6fw6q 3844 20 rate rate NN cord-006870-f5w6fw6q 3844 21 of of IN cord-006870-f5w6fw6q 3844 22 false false JJ cord-006870-f5w6fw6q 3844 23 - - HYPH cord-006870-f5w6fw6q 3844 24 positive positive JJ cord-006870-f5w6fw6q 3844 25 stroke stroke NN cord-006870-f5w6fw6q 3844 26 code code NN cord-006870-f5w6fw6q 3844 27 activations activation NNS cord-006870-f5w6fw6q 3844 28 . . . cord-006870-f5w6fw6q 3845 1 The the DT cord-006870-f5w6fw6q 3845 2 Nursing nursing NN cord-006870-f5w6fw6q 3845 3 - - HYPH cord-006870-f5w6fw6q 3845 4 driven drive VBN cord-006870-f5w6fw6q 3845 5 Acute Acute NNP cord-006870-f5w6fw6q 3845 6 Stroke Stroke NNP cord-006870-f5w6fw6q 3845 7 Care Care NNP cord-006870-f5w6fw6q 3845 8 ( ( -LRB- cord-006870-f5w6fw6q 3845 9 NAS NAS NNP cord-006870-f5w6fw6q 3845 10 - - HYPH cord-006870-f5w6fw6q 3845 11 Care Care NNP cord-006870-f5w6fw6q 3845 12 ) ) -RRB- cord-006870-f5w6fw6q 3845 13 study study NN cord-006870-f5w6fw6q 3845 14 aims aim VBZ cord-006870-f5w6fw6q 3845 15 to to TO cord-006870-f5w6fw6q 3845 16 determine determine VB cord-006870-f5w6fw6q 3845 17 if if IN cord-006870-f5w6fw6q 3845 18 implementing implement VBG cord-006870-f5w6fw6q 3845 19 a a DT cord-006870-f5w6fw6q 3845 20 standardized standardized JJ cord-006870-f5w6fw6q 3845 21 ED ED NNP cord-006870-f5w6fw6q 3845 22 stroke stroke NN cord-006870-f5w6fw6q 3845 23 program program NN cord-006870-f5w6fw6q 3845 24 decreases decrease VBZ cord-006870-f5w6fw6q 3845 25 door door NN cord-006870-f5w6fw6q 3845 26 - - HYPH cord-006870-f5w6fw6q 3845 27 to to IN cord-006870-f5w6fw6q 3845 28 - - HYPH cord-006870-f5w6fw6q 3845 29 needle needle NN cord-006870-f5w6fw6q 3845 30 times time NNS cord-006870-f5w6fw6q 3845 31 in in IN cord-006870-f5w6fw6q 3845 32 emergency emergency NN cord-006870-f5w6fw6q 3845 33 departments department NNS cord-006870-f5w6fw6q 3845 34 utilizing utilize VBG cord-006870-f5w6fw6q 3845 35 telemedicine telemedicine NN cord-006870-f5w6fw6q 3845 36 . . . cord-006870-f5w6fw6q 3846 1 The the DT cord-006870-f5w6fw6q 3846 2 NAS NAS NNP cord-006870-f5w6fw6q 3846 3 - - HYPH cord-006870-f5w6fw6q 3846 4 Care Care NNP cord-006870-f5w6fw6q 3846 5 intervention intervention NN cord-006870-f5w6fw6q 3846 6 consists consist VBZ cord-006870-f5w6fw6q 3846 7 of of IN cord-006870-f5w6fw6q 3846 8 ED ED NNP cord-006870-f5w6fw6q 3846 9 nursing nursing NN cord-006870-f5w6fw6q 3846 10 education education NN cord-006870-f5w6fw6q 3846 11 including include VBG cord-006870-f5w6fw6q 3846 12 mock mock JJ cord-006870-f5w6fw6q 3846 13 codes code NNS cord-006870-f5w6fw6q 3846 14 , , , cord-006870-f5w6fw6q 3846 15 NIHSS NIHSS NNP cord-006870-f5w6fw6q 3846 16 certification certification NN cord-006870-f5w6fw6q 3846 17 , , , cord-006870-f5w6fw6q 3846 18 and and CC cord-006870-f5w6fw6q 3846 19 implementation implementation NN cord-006870-f5w6fw6q 3846 20 of of IN cord-006870-f5w6fw6q 3846 21 a a DT cord-006870-f5w6fw6q 3846 22 standardized standardized JJ cord-006870-f5w6fw6q 3846 23 flow flow NN cord-006870-f5w6fw6q 3846 24 sheet sheet NN cord-006870-f5w6fw6q 3846 25 . . . cord-006870-f5w6fw6q 3847 1 In in IN cord-006870-f5w6fw6q 3847 2 this this DT cord-006870-f5w6fw6q 3847 3 interim interim JJ cord-006870-f5w6fw6q 3847 4 analysis analysis NN cord-006870-f5w6fw6q 3847 5 from from IN cord-006870-f5w6fw6q 3847 6 the the DT cord-006870-f5w6fw6q 3847 7 first first JJ cord-006870-f5w6fw6q 3847 8 4 4 CD cord-006870-f5w6fw6q 3847 9 ( ( -LRB- cord-006870-f5w6fw6q 3847 10 of of IN cord-006870-f5w6fw6q 3847 11 7 7 CD cord-006870-f5w6fw6q 3847 12 ) ) -RRB- cord-006870-f5w6fw6q 3847 13 NAS NAS NNP cord-006870-f5w6fw6q 3847 14 - - HYPH cord-006870-f5w6fw6q 3847 15 Care Care NNP cord-006870-f5w6fw6q 3847 16 study study NN cord-006870-f5w6fw6q 3847 17 hospitals hospital NNS cord-006870-f5w6fw6q 3847 18 , , , cord-006870-f5w6fw6q 3847 19 we -PRON- PRP cord-006870-f5w6fw6q 3847 20 examined examine VBD cord-006870-f5w6fw6q 3847 21 ED ED NNP cord-006870-f5w6fw6q 3847 22 admission admission NN cord-006870-f5w6fw6q 3847 23 and and CC cord-006870-f5w6fw6q 3847 24 discharge discharge NN cord-006870-f5w6fw6q 3847 25 diagnoses diagnosis NNS cord-006870-f5w6fw6q 3847 26 at at IN cord-006870-f5w6fw6q 3847 27 each each DT cord-006870-f5w6fw6q 3847 28 site site NN cord-006870-f5w6fw6q 3847 29 for for IN cord-006870-f5w6fw6q 3847 30 3 3 CD cord-006870-f5w6fw6q 3847 31 months month NNS cord-006870-f5w6fw6q 3847 32 of of IN cord-006870-f5w6fw6q 3847 33 blinded blinded JJ cord-006870-f5w6fw6q 3847 34 baseline baseline JJ cord-006870-f5w6fw6q 3847 35 data datum NNS cord-006870-f5w6fw6q 3847 36 collection collection NN cord-006870-f5w6fw6q 3847 37 ( ( -LRB- cord-006870-f5w6fw6q 3847 38 " " `` cord-006870-f5w6fw6q 3847 39 Control Control NNP cord-006870-f5w6fw6q 3847 40 " " '' cord-006870-f5w6fw6q 3847 41 ) ) -RRB- cord-006870-f5w6fw6q 3847 42 and and CC cord-006870-f5w6fw6q 3847 43 6 6 CD cord-006870-f5w6fw6q 3847 44 months month NNS cord-006870-f5w6fw6q 3847 45 after after IN cord-006870-f5w6fw6q 3847 46 standardized standardized JJ cord-006870-f5w6fw6q 3847 47 training training NN cord-006870-f5w6fw6q 3847 48 ( ( -LRB- cord-006870-f5w6fw6q 3847 49 " " `` cord-006870-f5w6fw6q 3847 50 Intervention Intervention NNP cord-006870-f5w6fw6q 3847 51 " " '' cord-006870-f5w6fw6q 3847 52 ) ) -RRB- cord-006870-f5w6fw6q 3847 53 . . . cord-006870-f5w6fw6q 3848 1 False false JJ cord-006870-f5w6fw6q 3848 2 - - HYPH cord-006870-f5w6fw6q 3848 3 positive positive JJ cord-006870-f5w6fw6q 3848 4 encounters encounter NNS cord-006870-f5w6fw6q 3848 5 were be VBD cord-006870-f5w6fw6q 3848 6 defined define VBN cord-006870-f5w6fw6q 3848 7 as as IN cord-006870-f5w6fw6q 3848 8 stroke stroke NN cord-006870-f5w6fw6q 3848 9 code code NN cord-006870-f5w6fw6q 3848 10 activations activation NNS cord-006870-f5w6fw6q 3848 11 for for IN cord-006870-f5w6fw6q 3848 12 which which WDT cord-006870-f5w6fw6q 3848 13 the the DT cord-006870-f5w6fw6q 3848 14 patient patient JJ cord-006870-f5w6fw6q 3848 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 3848 16 on on IN cord-006870-f5w6fw6q 3848 17 leaving leave VBG cord-006870-f5w6fw6q 3848 18 the the DT cord-006870-f5w6fw6q 3848 19 ED ED NNP cord-006870-f5w6fw6q 3848 20 was be VBD cord-006870-f5w6fw6q 3848 21 not not RB cord-006870-f5w6fw6q 3848 22 stroke stroke NN cord-006870-f5w6fw6q 3848 23 . . . cord-006870-f5w6fw6q 3848 24 _SP cord-006870-f5w6fw6q 3849 1 Although although IN cord-006870-f5w6fw6q 3849 2 hospitals hospital NNS cord-006870-f5w6fw6q 3849 3 trended trend VBD cord-006870-f5w6fw6q 3849 4 toward toward IN cord-006870-f5w6fw6q 3849 5 a a DT cord-006870-f5w6fw6q 3849 6 reduction reduction NN cord-006870-f5w6fw6q 3849 7 in in IN cord-006870-f5w6fw6q 3849 8 false false JJ cord-006870-f5w6fw6q 3849 9 - - HYPH cord-006870-f5w6fw6q 3849 10 positive positive JJ cord-006870-f5w6fw6q 3849 11 stroke stroke NN cord-006870-f5w6fw6q 3849 12 code code NN cord-006870-f5w6fw6q 3849 13 activations activation NNS cord-006870-f5w6fw6q 3849 14 after after IN cord-006870-f5w6fw6q 3849 15 implementation implementation NN cord-006870-f5w6fw6q 3849 16 of of IN cord-006870-f5w6fw6q 3849 17 the the DT cord-006870-f5w6fw6q 3849 18 standardized standardized JJ cord-006870-f5w6fw6q 3849 19 stroke stroke NN cord-006870-f5w6fw6q 3849 20 education education NN cord-006870-f5w6fw6q 3849 21 , , , cord-006870-f5w6fw6q 3849 22 mock mock JJ cord-006870-f5w6fw6q 3849 23 stroke stroke NN cord-006870-f5w6fw6q 3849 24 codes code NNS cord-006870-f5w6fw6q 3849 25 , , , cord-006870-f5w6fw6q 3849 26 and and CC cord-006870-f5w6fw6q 3849 27 flow flow NN cord-006870-f5w6fw6q 3849 28 sheet sheet NN cord-006870-f5w6fw6q 3849 29 , , , cord-006870-f5w6fw6q 3849 30 none none NN cord-006870-f5w6fw6q 3849 31 of of IN cord-006870-f5w6fw6q 3849 32 the the DT cord-006870-f5w6fw6q 3849 33 values value NNS cord-006870-f5w6fw6q 3849 34 were be VBD cord-006870-f5w6fw6q 3849 35 statistically statistically RB cord-006870-f5w6fw6q 3849 36 significant significant JJ cord-006870-f5w6fw6q 3849 37 . . . cord-006870-f5w6fw6q 3850 1 Further further JJ cord-006870-f5w6fw6q 3850 2 research research NN cord-006870-f5w6fw6q 3850 3 is be VBZ cord-006870-f5w6fw6q 3850 4 needed need VBN cord-006870-f5w6fw6q 3850 5 to to TO cord-006870-f5w6fw6q 3850 6 determine determine VB cord-006870-f5w6fw6q 3850 7 whether whether IN cord-006870-f5w6fw6q 3850 8 intensive intensive JJ cord-006870-f5w6fw6q 3850 9 ED ED NNP cord-006870-f5w6fw6q 3850 10 nursing nursing NN cord-006870-f5w6fw6q 3850 11 education education NN cord-006870-f5w6fw6q 3850 12 can can MD cord-006870-f5w6fw6q 3850 13 improve improve VB cord-006870-f5w6fw6q 3850 14 telestroke telestroke NNP cord-006870-f5w6fw6q 3850 15 resource resource NN cord-006870-f5w6fw6q 3850 16 utilization utilization NN cord-006870-f5w6fw6q 3850 17 . . . cord-006870-f5w6fw6q 3851 1 Pharmacist pharmacist NN cord-006870-f5w6fw6q 3851 2 - - HYPH cord-006870-f5w6fw6q 3851 3 driven drive VBN cord-006870-f5w6fw6q 3851 4 intravenous intravenous NN cord-006870-f5w6fw6q 3851 5 ( ( -LRB- cord-006870-f5w6fw6q 3851 6 IV IV NNP cord-006870-f5w6fw6q 3851 7 ) ) -RRB- cord-006870-f5w6fw6q 3851 8 to to IN cord-006870-f5w6fw6q 3851 9 oral oral JJ cord-006870-f5w6fw6q 3851 10 ( ( -LRB- cord-006870-f5w6fw6q 3851 11 PO po NN cord-006870-f5w6fw6q 3851 12 ) ) -RRB- cord-006870-f5w6fw6q 3851 13 conversion conversion NN cord-006870-f5w6fw6q 3851 14 protocols protocol NNS cord-006870-f5w6fw6q 3851 15 result result VBP cord-006870-f5w6fw6q 3851 16 in in IN cord-006870-f5w6fw6q 3851 17 greater great JJR cord-006870-f5w6fw6q 3851 18 compliance compliance NN cord-006870-f5w6fw6q 3851 19 , , , cord-006870-f5w6fw6q 3851 20 improved improve VBN cord-006870-f5w6fw6q 3851 21 cost cost NN cord-006870-f5w6fw6q 3851 22 - - HYPH cord-006870-f5w6fw6q 3851 23 savings saving NNS cord-006870-f5w6fw6q 3851 24 , , , cord-006870-f5w6fw6q 3851 25 and and CC cord-006870-f5w6fw6q 3851 26 better well JJR cord-006870-f5w6fw6q 3851 27 patient patient JJ cord-006870-f5w6fw6q 3851 28 outcomes outcome NNS cord-006870-f5w6fw6q 3851 29 related relate VBN cord-006870-f5w6fw6q 3851 30 to to IN cord-006870-f5w6fw6q 3851 31 length length NN cord-006870-f5w6fw6q 3851 32 of of IN cord-006870-f5w6fw6q 3851 33 stay stay NN cord-006870-f5w6fw6q 3851 34 , , , cord-006870-f5w6fw6q 3851 35 re re NN cord-006870-f5w6fw6q 3851 36 - - NN cord-006870-f5w6fw6q 3851 37 admission admission NN cord-006870-f5w6fw6q 3851 38 , , , cord-006870-f5w6fw6q 3851 39 and and CC cord-006870-f5w6fw6q 3851 40 duration duration NN cord-006870-f5w6fw6q 3851 41 of of IN cord-006870-f5w6fw6q 3851 42 intravenous intravenous JJ cord-006870-f5w6fw6q 3851 43 therapy therapy NN cord-006870-f5w6fw6q 3851 44 . . . cord-006870-f5w6fw6q 3852 1 This this DT cord-006870-f5w6fw6q 3852 2 study study NN cord-006870-f5w6fw6q 3852 3 aims aim VBZ cord-006870-f5w6fw6q 3852 4 to to TO cord-006870-f5w6fw6q 3852 5 determine determine VB cord-006870-f5w6fw6q 3852 6 the the DT cord-006870-f5w6fw6q 3852 7 cost cost NN cord-006870-f5w6fw6q 3852 8 - - HYPH cord-006870-f5w6fw6q 3852 9 savings saving NNS cord-006870-f5w6fw6q 3852 10 and and CC cord-006870-f5w6fw6q 3852 11 patient patient JJ cord-006870-f5w6fw6q 3852 12 impacts impact NNS cord-006870-f5w6fw6q 3852 13 of of IN cord-006870-f5w6fw6q 3852 14 such such PDT cord-006870-f5w6fw6q 3852 15 a a DT cord-006870-f5w6fw6q 3852 16 conversion conversion NN cord-006870-f5w6fw6q 3852 17 protocol protocol NN cord-006870-f5w6fw6q 3852 18 for for IN cord-006870-f5w6fw6q 3852 19 anti anti JJ cord-006870-f5w6fw6q 3852 20 - - JJ cord-006870-f5w6fw6q 3852 21 epileptic epileptic JJ cord-006870-f5w6fw6q 3852 22 drugs drug NNS cord-006870-f5w6fw6q 3852 23 ( ( -LRB- cord-006870-f5w6fw6q 3852 24 AEDs aed NNS cord-006870-f5w6fw6q 3852 25 ) ) -RRB- cord-006870-f5w6fw6q 3852 26 including include VBG cord-006870-f5w6fw6q 3852 27 lacosamide lacosamide NN cord-006870-f5w6fw6q 3852 28 , , , cord-006870-f5w6fw6q 3852 29 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 3852 30 , , , cord-006870-f5w6fw6q 3852 31 phenytoin phenytoin NN cord-006870-f5w6fw6q 3852 32 , , , cord-006870-f5w6fw6q 3852 33 and and CC cord-006870-f5w6fw6q 3852 34 valproic valproic NN cord-006870-f5w6fw6q 3852 35 acid acid NN cord-006870-f5w6fw6q 3852 36 . . . cord-006870-f5w6fw6q 3853 1 A a DT cord-006870-f5w6fw6q 3853 2 retrospective retrospective JJ cord-006870-f5w6fw6q 3853 3 , , , cord-006870-f5w6fw6q 3853 4 observational observational JJ cord-006870-f5w6fw6q 3853 5 phase phase NN cord-006870-f5w6fw6q 3853 6 was be VBD cord-006870-f5w6fw6q 3853 7 conducted conduct VBN cord-006870-f5w6fw6q 3853 8 to to TO cord-006870-f5w6fw6q 3853 9 determine determine VB cord-006870-f5w6fw6q 3853 10 usual usual JJ cord-006870-f5w6fw6q 3853 11 practice practice NN cord-006870-f5w6fw6q 3853 12 patterns pattern NNS cord-006870-f5w6fw6q 3853 13 concerning concern VBG cord-006870-f5w6fw6q 3853 14 conversion conversion NN cord-006870-f5w6fw6q 3853 15 to to IN cord-006870-f5w6fw6q 3853 16 oral oral JJ cord-006870-f5w6fw6q 3853 17 therapy therapy NN cord-006870-f5w6fw6q 3853 18 between between IN cord-006870-f5w6fw6q 3853 19 11/1/2016 11/1/2016 CD cord-006870-f5w6fw6q 3853 20 and and CC cord-006870-f5w6fw6q 3853 21 11/30/2016 11/30/2016 CD cord-006870-f5w6fw6q 3853 22 . . . cord-006870-f5w6fw6q 3854 1 The the DT cord-006870-f5w6fw6q 3854 2 conversion conversion NN cord-006870-f5w6fw6q 3854 3 protocol protocol NN cord-006870-f5w6fw6q 3854 4 was be VBD cord-006870-f5w6fw6q 3854 5 approved approve VBN cord-006870-f5w6fw6q 3854 6 in in IN cord-006870-f5w6fw6q 3854 7 December December NNP cord-006870-f5w6fw6q 3854 8 2016 2016 CD cord-006870-f5w6fw6q 3854 9 and and CC cord-006870-f5w6fw6q 3854 10 implemented implement VBD cord-006870-f5w6fw6q 3854 11 in in IN cord-006870-f5w6fw6q 3854 12 January January NNP cord-006870-f5w6fw6q 3854 13 2017 2017 CD cord-006870-f5w6fw6q 3854 14 . . . cord-006870-f5w6fw6q 3855 1 A a DT cord-006870-f5w6fw6q 3855 2 second second JJ cord-006870-f5w6fw6q 3855 3 retrospective retrospective JJ cord-006870-f5w6fw6q 3855 4 phase phase NN cord-006870-f5w6fw6q 3855 5 observed observe VBD cord-006870-f5w6fw6q 3855 6 conversion conversion NN cord-006870-f5w6fw6q 3855 7 practices practice NNS cord-006870-f5w6fw6q 3855 8 beginning begin VBG cord-006870-f5w6fw6q 3855 9 02/01/2017 02/01/2017 CD cord-006870-f5w6fw6q 3855 10 and and CC cord-006870-f5w6fw6q 3855 11 ending end VBG cord-006870-f5w6fw6q 3855 12 03/02/2017 03/02/2017 CD cord-006870-f5w6fw6q 3855 13 . . . cord-006870-f5w6fw6q 3856 1 Length length NN cord-006870-f5w6fw6q 3856 2 of of IN cord-006870-f5w6fw6q 3856 3 intravenous intravenous JJ cord-006870-f5w6fw6q 3856 4 and and CC cord-006870-f5w6fw6q 3856 5 oral oral JJ cord-006870-f5w6fw6q 3856 6 therapy therapy NN cord-006870-f5w6fw6q 3856 7 , , , cord-006870-f5w6fw6q 3856 8 date date NN cord-006870-f5w6fw6q 3856 9 eligible eligible JJ cord-006870-f5w6fw6q 3856 10 for for IN cord-006870-f5w6fw6q 3856 11 conversion conversion NN cord-006870-f5w6fw6q 3856 12 , , , cord-006870-f5w6fw6q 3856 13 and and CC cord-006870-f5w6fw6q 3856 14 date date NN cord-006870-f5w6fw6q 3856 15 of of IN cord-006870-f5w6fw6q 3856 16 conversion conversion NN cord-006870-f5w6fw6q 3856 17 were be VBD cord-006870-f5w6fw6q 3856 18 recorded record VBN cord-006870-f5w6fw6q 3856 19 . . . cord-006870-f5w6fw6q 3857 1 Hospital hospital NN cord-006870-f5w6fw6q 3857 2 acquisition acquisition NN cord-006870-f5w6fw6q 3857 3 costs cost NNS cord-006870-f5w6fw6q 3857 4 were be VBD cord-006870-f5w6fw6q 3857 5 utilized utilize VBN cord-006870-f5w6fw6q 3857 6 for for IN cord-006870-f5w6fw6q 3857 7 medication medication NN cord-006870-f5w6fw6q 3857 8 expenditure expenditure NN cord-006870-f5w6fw6q 3857 9 calculations calculation NNS cord-006870-f5w6fw6q 3857 10 . . . cord-006870-f5w6fw6q 3858 1 This this DT cord-006870-f5w6fw6q 3858 2 information information NN cord-006870-f5w6fw6q 3858 3 was be VBD cord-006870-f5w6fw6q 3858 4 used use VBN cord-006870-f5w6fw6q 3858 5 to to TO cord-006870-f5w6fw6q 3858 6 determine determine VB cord-006870-f5w6fw6q 3858 7 financial financial JJ cord-006870-f5w6fw6q 3858 8 impact impact NN cord-006870-f5w6fw6q 3858 9 of of IN cord-006870-f5w6fw6q 3858 10 the the DT cord-006870-f5w6fw6q 3858 11 protocol protocol NN cord-006870-f5w6fw6q 3858 12 and and CC cord-006870-f5w6fw6q 3858 13 is be VBZ cord-006870-f5w6fw6q 3858 14 presented present VBN cord-006870-f5w6fw6q 3858 15 as as IN cord-006870-f5w6fw6q 3858 16 descriptive descriptive JJ cord-006870-f5w6fw6q 3858 17 endpoints endpoint NNS cord-006870-f5w6fw6q 3858 18 . . . cord-006870-f5w6fw6q 3859 1 Adverse adverse JJ cord-006870-f5w6fw6q 3859 2 drug drug NN cord-006870-f5w6fw6q 3859 3 events event NNS cord-006870-f5w6fw6q 3859 4 were be VBD cord-006870-f5w6fw6q 3859 5 collected collect VBN cord-006870-f5w6fw6q 3859 6 via via IN cord-006870-f5w6fw6q 3859 7 an an DT cord-006870-f5w6fw6q 3859 8 institutional institutional JJ cord-006870-f5w6fw6q 3859 9 incident incident NN cord-006870-f5w6fw6q 3859 10 reporting report VBG cord-006870-f5w6fw6q 3859 11 system system NN cord-006870-f5w6fw6q 3859 12 . . . cord-006870-f5w6fw6q 3860 1 A a DT cord-006870-f5w6fw6q 3860 2 total total NN cord-006870-f5w6fw6q 3860 3 of of IN cord-006870-f5w6fw6q 3860 4 408 408 CD cord-006870-f5w6fw6q 3860 5 encounters encounter NNS cord-006870-f5w6fw6q 3860 6 were be VBD cord-006870-f5w6fw6q 3860 7 identified identify VBN cord-006870-f5w6fw6q 3860 8 , , , cord-006870-f5w6fw6q 3860 9 resulting result VBG cord-006870-f5w6fw6q 3860 10 in in IN cord-006870-f5w6fw6q 3860 11 147 147 CD cord-006870-f5w6fw6q 3860 12 encounters encounter NNS cord-006870-f5w6fw6q 3860 13 in in IN cord-006870-f5w6fw6q 3860 14 the the DT cord-006870-f5w6fw6q 3860 15 pre pre NN cord-006870-f5w6fw6q 3860 16 - - JJ cord-006870-f5w6fw6q 3860 17 cohort cohort JJ cord-006870-f5w6fw6q 3860 18 and and CC cord-006870-f5w6fw6q 3860 19 121 121 CD cord-006870-f5w6fw6q 3860 20 postcohort postcohort NN cord-006870-f5w6fw6q 3860 21 encounters encounter NNS cord-006870-f5w6fw6q 3860 22 . . . cord-006870-f5w6fw6q 3861 1 Looking look VBG cord-006870-f5w6fw6q 3861 2 at at IN cord-006870-f5w6fw6q 3861 3 the the DT cord-006870-f5w6fw6q 3861 4 pre pre JJ cord-006870-f5w6fw6q 3861 5 and and CC cord-006870-f5w6fw6q 3861 6 post post VB cord-006870-f5w6fw6q 3861 7 cohorts cohort NNS cord-006870-f5w6fw6q 3861 8 respectively respectively RB cord-006870-f5w6fw6q 3861 9 , , , cord-006870-f5w6fw6q 3861 10 both both DT cord-006870-f5w6fw6q 3861 11 cohorts cohort NNS cord-006870-f5w6fw6q 3861 12 had have VBD cord-006870-f5w6fw6q 3861 13 similar similar JJ cord-006870-f5w6fw6q 3861 14 median median JJ cord-006870-f5w6fw6q 3861 15 lengths length NNS cord-006870-f5w6fw6q 3861 16 of of IN cord-006870-f5w6fw6q 3861 17 stay stay NN cord-006870-f5w6fw6q 3861 18 ( ( -LRB- cord-006870-f5w6fw6q 3861 19 11 11 CD cord-006870-f5w6fw6q 3861 20 days day NNS cord-006870-f5w6fw6q 3861 21 vs. vs. IN cord-006870-f5w6fw6q 3861 22 9 9 CD cord-006870-f5w6fw6q 3861 23 days day NNS cord-006870-f5w6fw6q 3861 24 ) ) -RRB- cord-006870-f5w6fw6q 3861 25 , , , cord-006870-f5w6fw6q 3861 26 30-day 30-day CD cord-006870-f5w6fw6q 3861 27 readmission readmission NN cord-006870-f5w6fw6q 3861 28 rates rate NNS cord-006870-f5w6fw6q 3861 29 ( ( -LRB- cord-006870-f5w6fw6q 3861 30 6.8 6.8 CD cord-006870-f5w6fw6q 3861 31 % % NN cord-006870-f5w6fw6q 3861 32 vs vs IN cord-006870-f5w6fw6q 3861 33 9.9 9.9 CD cord-006870-f5w6fw6q 3861 34 % % NN cord-006870-f5w6fw6q 3861 35 ) ) -RRB- cord-006870-f5w6fw6q 3861 36 , , , cord-006870-f5w6fw6q 3861 37 and and CC cord-006870-f5w6fw6q 3861 38 rates rate NNS cord-006870-f5w6fw6q 3861 39 of of IN cord-006870-f5w6fw6q 3861 40 conversion conversion NN cord-006870-f5w6fw6q 3861 41 from from IN cord-006870-f5w6fw6q 3861 42 oral oral JJ cord-006870-f5w6fw6q 3861 43 back back RB cord-006870-f5w6fw6q 3861 44 to to IN cord-006870-f5w6fw6q 3861 45 intravenous intravenous JJ cord-006870-f5w6fw6q 3861 46 therapy therapy NN cord-006870-f5w6fw6q 3861 47 ( ( -LRB- cord-006870-f5w6fw6q 3861 48 6.8 6.8 CD cord-006870-f5w6fw6q 3861 49 % % NN cord-006870-f5w6fw6q 3861 50 vs vs IN cord-006870-f5w6fw6q 3861 51 6.6 6.6 CD cord-006870-f5w6fw6q 3861 52 % % NN cord-006870-f5w6fw6q 3861 53 ) ) -RRB- cord-006870-f5w6fw6q 3861 54 . . . cord-006870-f5w6fw6q 3862 1 The the DT cord-006870-f5w6fw6q 3862 2 median median JJ cord-006870-f5w6fw6q 3862 3 length length NN cord-006870-f5w6fw6q 3862 4 of of IN cord-006870-f5w6fw6q 3862 5 intravenous intravenous JJ cord-006870-f5w6fw6q 3862 6 therapy therapy NN cord-006870-f5w6fw6q 3862 7 was be VBD cord-006870-f5w6fw6q 3862 8 5 5 CD cord-006870-f5w6fw6q 3862 9 days day NNS cord-006870-f5w6fw6q 3862 10 prior prior RB cord-006870-f5w6fw6q 3862 11 to to IN cord-006870-f5w6fw6q 3862 12 protocol protocol NN cord-006870-f5w6fw6q 3862 13 implementation implementation NN cord-006870-f5w6fw6q 3862 14 and and CC cord-006870-f5w6fw6q 3862 15 decreased decrease VBD cord-006870-f5w6fw6q 3862 16 to to IN cord-006870-f5w6fw6q 3862 17 3 3 CD cord-006870-f5w6fw6q 3862 18 days day NNS cord-006870-f5w6fw6q 3862 19 in in IN cord-006870-f5w6fw6q 3862 20 the the DT cord-006870-f5w6fw6q 3862 21 post post NN cord-006870-f5w6fw6q 3862 22 - - JJ cord-006870-f5w6fw6q 3862 23 cohort cohort JJ cord-006870-f5w6fw6q 3862 24 . . . cord-006870-f5w6fw6q 3863 1 The the DT cord-006870-f5w6fw6q 3863 2 average average JJ cord-006870-f5w6fw6q 3863 3 cost cost NN cord-006870-f5w6fw6q 3863 4 per per IN cord-006870-f5w6fw6q 3863 5 day day NN cord-006870-f5w6fw6q 3863 6 of of IN cord-006870-f5w6fw6q 3863 7 AED AED NNP cord-006870-f5w6fw6q 3863 8 therapy therapy NN cord-006870-f5w6fw6q 3863 9 was be VBD cord-006870-f5w6fw6q 3863 10 $ $ $ cord-006870-f5w6fw6q 3863 11 10.36 10.36 CD cord-006870-f5w6fw6q 3863 12 in in IN cord-006870-f5w6fw6q 3863 13 the the DT cord-006870-f5w6fw6q 3863 14 pre pre NN cord-006870-f5w6fw6q 3863 15 - - JJ cord-006870-f5w6fw6q 3863 16 cohort cohort JJ cord-006870-f5w6fw6q 3863 17 but but CC cord-006870-f5w6fw6q 3863 18 decreased decrease VBD cord-006870-f5w6fw6q 3863 19 to to IN cord-006870-f5w6fw6q 3863 20 $ $ $ cord-006870-f5w6fw6q 3863 21 4.46 4.46 CD cord-006870-f5w6fw6q 3863 22 in in IN cord-006870-f5w6fw6q 3863 23 the the DT cord-006870-f5w6fw6q 3863 24 post post NN cord-006870-f5w6fw6q 3863 25 - - JJ cord-006870-f5w6fw6q 3863 26 cohort cohort JJ cord-006870-f5w6fw6q 3863 27 . . . cord-006870-f5w6fw6q 3864 1 Median median JJ cord-006870-f5w6fw6q 3864 2 missed miss VBN cord-006870-f5w6fw6q 3864 3 opportunity opportunity NN cord-006870-f5w6fw6q 3864 4 costs cost NNS cord-006870-f5w6fw6q 3864 5 , , , cord-006870-f5w6fw6q 3864 6 defined define VBN cord-006870-f5w6fw6q 3864 7 as as IN cord-006870-f5w6fw6q 3864 8 the the DT cord-006870-f5w6fw6q 3864 9 cost cost NN cord-006870-f5w6fw6q 3864 10 savings saving NNS cord-006870-f5w6fw6q 3864 11 if if IN cord-006870-f5w6fw6q 3864 12 conversion conversion NN cord-006870-f5w6fw6q 3864 13 occurred occur VBD cord-006870-f5w6fw6q 3864 14 at at IN cord-006870-f5w6fw6q 3864 15 the the DT cord-006870-f5w6fw6q 3864 16 earliest early JJS cord-006870-f5w6fw6q 3864 17 possible possible JJ cord-006870-f5w6fw6q 3864 18 date date NN cord-006870-f5w6fw6q 3864 19 , , , cord-006870-f5w6fw6q 3864 20 also also RB cord-006870-f5w6fw6q 3864 21 decreased decrease VBD cord-006870-f5w6fw6q 3864 22 between between IN cord-006870-f5w6fw6q 3864 23 the the DT cord-006870-f5w6fw6q 3864 24 cohorts cohort NNS cord-006870-f5w6fw6q 3864 25 from from IN cord-006870-f5w6fw6q 3864 26 $ $ $ cord-006870-f5w6fw6q 3864 27 3.87 3.87 CD cord-006870-f5w6fw6q 3864 28 to to IN cord-006870-f5w6fw6q 3864 29 $ $ $ cord-006870-f5w6fw6q 3864 30 1.24 1.24 CD cord-006870-f5w6fw6q 3864 31 . . . cord-006870-f5w6fw6q 3865 1 Pharmacist pharmacist NN cord-006870-f5w6fw6q 3865 2 involvement involvement NN cord-006870-f5w6fw6q 3865 3 in in IN cord-006870-f5w6fw6q 3865 4 AED AED NNP cord-006870-f5w6fw6q 3865 5 conversion conversion NN cord-006870-f5w6fw6q 3865 6 had have VBD cord-006870-f5w6fw6q 3865 7 a a DT cord-006870-f5w6fw6q 3865 8 positive positive JJ cord-006870-f5w6fw6q 3865 9 financial financial JJ cord-006870-f5w6fw6q 3865 10 impact impact NN cord-006870-f5w6fw6q 3865 11 without without IN cord-006870-f5w6fw6q 3865 12 compromising compromise VBG cord-006870-f5w6fw6q 3865 13 patient patient JJ cord-006870-f5w6fw6q 3865 14 care care NN cord-006870-f5w6fw6q 3865 15 . . . cord-006870-f5w6fw6q 3866 1 The the DT cord-006870-f5w6fw6q 3866 2 National National NNP cord-006870-f5w6fw6q 3866 3 Institute Institute NNP cord-006870-f5w6fw6q 3866 4 of of IN cord-006870-f5w6fw6q 3866 5 Neurological Neurological NNP cord-006870-f5w6fw6q 3866 6 Disorders Disorders NNPS cord-006870-f5w6fw6q 3866 7 and and CC cord-006870-f5w6fw6q 3866 8 Stroke Stroke NNP cord-006870-f5w6fw6q 3866 9 ( ( -LRB- cord-006870-f5w6fw6q 3866 10 NINDS NINDS NNP cord-006870-f5w6fw6q 3866 11 ) ) -RRB- cord-006870-f5w6fw6q 3866 12 established establish VBD cord-006870-f5w6fw6q 3866 13 the the DT cord-006870-f5w6fw6q 3866 14 NIH NIH NNP cord-006870-f5w6fw6q 3866 15 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3866 16 to to TO cord-006870-f5w6fw6q 3866 17 facilitate facilitate VB cord-006870-f5w6fw6q 3866 18 the the DT cord-006870-f5w6fw6q 3866 19 rapid rapid JJ cord-006870-f5w6fw6q 3866 20 initiation initiation NN cord-006870-f5w6fw6q 3866 21 and and CC cord-006870-f5w6fw6q 3866 22 efficient efficient JJ cord-006870-f5w6fw6q 3866 23 implementation implementation NN cord-006870-f5w6fw6q 3866 24 of of IN cord-006870-f5w6fw6q 3866 25 multi multi JJ cord-006870-f5w6fw6q 3866 26 - - JJ cord-006870-f5w6fw6q 3866 27 center center JJ cord-006870-f5w6fw6q 3866 28 exploratory exploratory JJ cord-006870-f5w6fw6q 3866 29 and and CC cord-006870-f5w6fw6q 3866 30 confirmatory confirmatory JJ cord-006870-f5w6fw6q 3866 31 clinical clinical JJ cord-006870-f5w6fw6q 3866 32 trials trial NNS cord-006870-f5w6fw6q 3866 33 focused focus VBD cord-006870-f5w6fw6q 3866 34 on on IN cord-006870-f5w6fw6q 3866 35 promising promising JJ cord-006870-f5w6fw6q 3866 36 interventions intervention NNS cord-006870-f5w6fw6q 3866 37 in in IN cord-006870-f5w6fw6q 3866 38 stroke stroke NN cord-006870-f5w6fw6q 3866 39 prevention prevention NN cord-006870-f5w6fw6q 3866 40 , , , cord-006870-f5w6fw6q 3866 41 treatment treatment NN cord-006870-f5w6fw6q 3866 42 , , , cord-006870-f5w6fw6q 3866 43 and and CC cord-006870-f5w6fw6q 3866 44 recovery recovery NN cord-006870-f5w6fw6q 3866 45 . . . cord-006870-f5w6fw6q 3867 1 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3867 2 was be VBD cord-006870-f5w6fw6q 3867 3 initiated initiate VBN cord-006870-f5w6fw6q 3867 4 in in IN cord-006870-f5w6fw6q 3867 5 the the DT cord-006870-f5w6fw6q 3867 6 Fall Fall NNP cord-006870-f5w6fw6q 3867 7 2013 2013 CD cord-006870-f5w6fw6q 3867 8 , , , cord-006870-f5w6fw6q 3867 9 and and CC cord-006870-f5w6fw6q 3867 10 involves involve VBZ cord-006870-f5w6fw6q 3867 11 over over IN cord-006870-f5w6fw6q 3867 12 350 350 CD cord-006870-f5w6fw6q 3867 13 hospitals hospital NNS cord-006870-f5w6fw6q 3867 14 across across IN cord-006870-f5w6fw6q 3867 15 the the DT cord-006870-f5w6fw6q 3867 16 US US NNP cord-006870-f5w6fw6q 3867 17 . . . cord-006870-f5w6fw6q 3868 1 The the DT cord-006870-f5w6fw6q 3868 2 network network NN cord-006870-f5w6fw6q 3868 3 is be VBZ cord-006870-f5w6fw6q 3868 4 anchored anchor VBN cord-006870-f5w6fw6q 3868 5 by by IN cord-006870-f5w6fw6q 3868 6 25 25 CD cord-006870-f5w6fw6q 3868 7 Regional Regional NNP cord-006870-f5w6fw6q 3868 8 Coordinating Coordinating NNP cord-006870-f5w6fw6q 3868 9 Centers Centers NNPS cord-006870-f5w6fw6q 3868 10 ( ( -LRB- cord-006870-f5w6fw6q 3868 11 RCCs rccs NN cord-006870-f5w6fw6q 3868 12 ) ) -RRB- cord-006870-f5w6fw6q 3868 13 , , , cord-006870-f5w6fw6q 3868 14 along along IN cord-006870-f5w6fw6q 3868 15 with with IN cord-006870-f5w6fw6q 3868 16 the the DT cord-006870-f5w6fw6q 3868 17 National National NNP cord-006870-f5w6fw6q 3868 18 Coordinating Coordinating NNP cord-006870-f5w6fw6q 3868 19 Center Center NNP cord-006870-f5w6fw6q 3868 20 ( ( -LRB- cord-006870-f5w6fw6q 3868 21 NCC NCC NNP cord-006870-f5w6fw6q 3868 22 ) ) -RRB- cord-006870-f5w6fw6q 3868 23 at at IN cord-006870-f5w6fw6q 3868 24 the the DT cord-006870-f5w6fw6q 3868 25 University University NNP cord-006870-f5w6fw6q 3868 26 of of IN cord-006870-f5w6fw6q 3868 27 Cincinnati Cincinnati NNP cord-006870-f5w6fw6q 3868 28 and and CC cord-006870-f5w6fw6q 3868 29 National National NNP cord-006870-f5w6fw6q 3868 30 Data Data NNP cord-006870-f5w6fw6q 3868 31 Management Management NNP cord-006870-f5w6fw6q 3868 32 Center Center NNP cord-006870-f5w6fw6q 3868 33 ( ( -LRB- cord-006870-f5w6fw6q 3868 34 NDMC NDMC NNP cord-006870-f5w6fw6q 3868 35 ) ) -RRB- cord-006870-f5w6fw6q 3868 36 at at IN cord-006870-f5w6fw6q 3868 37 the the DT cord-006870-f5w6fw6q 3868 38 Medical Medical NNP cord-006870-f5w6fw6q 3868 39 University University NNP cord-006870-f5w6fw6q 3868 40 of of IN cord-006870-f5w6fw6q 3868 41 South South NNP cord-006870-f5w6fw6q 3868 42 Carolina Carolina NNP cord-006870-f5w6fw6q 3868 43 , , , cord-006870-f5w6fw6q 3868 44 as as RB cord-006870-f5w6fw6q 3868 45 well well RB cord-006870-f5w6fw6q 3868 46 as as IN cord-006870-f5w6fw6q 3868 47 active active JJ cord-006870-f5w6fw6q 3868 48 participation participation NN cord-006870-f5w6fw6q 3868 49 by by IN cord-006870-f5w6fw6q 3868 50 the the DT cord-006870-f5w6fw6q 3868 51 NINDS NINDS NNP cord-006870-f5w6fw6q 3868 52 . . . cord-006870-f5w6fw6q 3869 1 One one CD cord-006870-f5w6fw6q 3869 2 of of IN cord-006870-f5w6fw6q 3869 3 the the DT cord-006870-f5w6fw6q 3869 4 primary primary JJ cord-006870-f5w6fw6q 3869 5 goals goal NNS cord-006870-f5w6fw6q 3869 6 of of IN cord-006870-f5w6fw6q 3869 7 the the DT cord-006870-f5w6fw6q 3869 8 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3869 9 is be VBZ cord-006870-f5w6fw6q 3869 10 to to TO cord-006870-f5w6fw6q 3869 11 serve serve VB cord-006870-f5w6fw6q 3869 12 as as IN cord-006870-f5w6fw6q 3869 13 the the DT cord-006870-f5w6fw6q 3869 14 primary primary JJ cord-006870-f5w6fw6q 3869 15 infrastructure infrastructure NN cord-006870-f5w6fw6q 3869 16 for for IN cord-006870-f5w6fw6q 3869 17 conducting conduct VBG cord-006870-f5w6fw6q 3869 18 stroke stroke NN cord-006870-f5w6fw6q 3869 19 clinical clinical JJ cord-006870-f5w6fw6q 3869 20 trials trial NNS cord-006870-f5w6fw6q 3869 21 and and CC cord-006870-f5w6fw6q 3869 22 pipeline pipeline NN cord-006870-f5w6fw6q 3869 23 for for IN cord-006870-f5w6fw6q 3869 24 new new JJ cord-006870-f5w6fw6q 3869 25 potential potential JJ cord-006870-f5w6fw6q 3869 26 treatments treatment NNS cord-006870-f5w6fw6q 3869 27 . . . cord-006870-f5w6fw6q 3870 1 To to TO cord-006870-f5w6fw6q 3870 2 maximize maximize VB cord-006870-f5w6fw6q 3870 3 the the DT cord-006870-f5w6fw6q 3870 4 impact impact NN cord-006870-f5w6fw6q 3870 5 of of IN cord-006870-f5w6fw6q 3870 6 NIH NIH NNP cord-006870-f5w6fw6q 3870 7 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3870 8 , , , cord-006870-f5w6fw6q 3870 9 it -PRON- PRP cord-006870-f5w6fw6q 3870 10 is be VBZ cord-006870-f5w6fw6q 3870 11 important important JJ cord-006870-f5w6fw6q 3870 12 for for IN cord-006870-f5w6fw6q 3870 13 the the DT cord-006870-f5w6fw6q 3870 14 larger large JJR cord-006870-f5w6fw6q 3870 15 community community NN cord-006870-f5w6fw6q 3870 16 of of IN cord-006870-f5w6fw6q 3870 17 stroke stroke NN cord-006870-f5w6fw6q 3870 18 researchers researcher NNS cord-006870-f5w6fw6q 3870 19 and and CC cord-006870-f5w6fw6q 3870 20 clinicians clinician NNS cord-006870-f5w6fw6q 3870 21 , , , cord-006870-f5w6fw6q 3870 22 including include VBG cord-006870-f5w6fw6q 3870 23 the the DT cord-006870-f5w6fw6q 3870 24 neurocritical neurocritical JJ cord-006870-f5w6fw6q 3870 25 care care NN cord-006870-f5w6fw6q 3870 26 specialists specialist NNS cord-006870-f5w6fw6q 3870 27 , , , cord-006870-f5w6fw6q 3870 28 to to TO cord-006870-f5w6fw6q 3870 29 know know VB cord-006870-f5w6fw6q 3870 30 its -PRON- PRP$ cord-006870-f5w6fw6q 3870 31 structure structure NN cord-006870-f5w6fw6q 3870 32 and and CC cord-006870-f5w6fw6q 3870 33 the the DT cord-006870-f5w6fw6q 3870 34 process process NN cord-006870-f5w6fw6q 3870 35 and and CC cord-006870-f5w6fw6q 3870 36 timeline timeline NN cord-006870-f5w6fw6q 3870 37 by by IN cord-006870-f5w6fw6q 3870 38 which which WDT cord-006870-f5w6fw6q 3870 39 stroke stroke NN cord-006870-f5w6fw6q 3870 40 trials trial NNS cord-006870-f5w6fw6q 3870 41 are be VBP cord-006870-f5w6fw6q 3870 42 developed develop VBN cord-006870-f5w6fw6q 3870 43 and and CC cord-006870-f5w6fw6q 3870 44 implemented implement VBN cord-006870-f5w6fw6q 3870 45 . . . cord-006870-f5w6fw6q 3871 1 Since since IN cord-006870-f5w6fw6q 3871 2 the the DT cord-006870-f5w6fw6q 3871 3 inception inception NN cord-006870-f5w6fw6q 3871 4 of of IN cord-006870-f5w6fw6q 3871 5 the the DT cord-006870-f5w6fw6q 3871 6 network network NN cord-006870-f5w6fw6q 3871 7 , , , cord-006870-f5w6fw6q 3871 8 49 49 CD cord-006870-f5w6fw6q 3871 9 * * NFP cord-006870-f5w6fw6q 3871 10 proposal proposal NN cord-006870-f5w6fw6q 3871 11 concepts concept NNS cord-006870-f5w6fw6q 3871 12 have have VBP cord-006870-f5w6fw6q 3871 13 been be VBN cord-006870-f5w6fw6q 3871 14 submitted submit VBN cord-006870-f5w6fw6q 3871 15 to to IN cord-006870-f5w6fw6q 3871 16 the the DT cord-006870-f5w6fw6q 3871 17 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3871 18 and and CC cord-006870-f5w6fw6q 3871 19 are be VBP cord-006870-f5w6fw6q 3871 20 in in IN cord-006870-f5w6fw6q 3871 21 different different JJ cord-006870-f5w6fw6q 3871 22 development development NN cord-006870-f5w6fw6q 3871 23 stages stage NNS cord-006870-f5w6fw6q 3871 24 . . . cord-006870-f5w6fw6q 3872 1 Among among IN cord-006870-f5w6fw6q 3872 2 those those DT cord-006870-f5w6fw6q 3872 3 evaluated evaluate VBN cord-006870-f5w6fw6q 3872 4 to to TO cord-006870-f5w6fw6q 3872 5 obtain obtain VB cord-006870-f5w6fw6q 3872 6 NINDS NINDS NNP cord-006870-f5w6fw6q 3872 7 permission permission NN cord-006870-f5w6fw6q 3872 8 to to TO cord-006870-f5w6fw6q 3872 9 submit submit VB cord-006870-f5w6fw6q 3872 10 a a DT cord-006870-f5w6fw6q 3872 11 grant grant NN cord-006870-f5w6fw6q 3872 12 application application NN cord-006870-f5w6fw6q 3872 13 , , , cord-006870-f5w6fw6q 3872 14 16 16 CD cord-006870-f5w6fw6q 3872 15 have have VBP cord-006870-f5w6fw6q 3872 16 submitted submit VBN cord-006870-f5w6fw6q 3872 17 and and CC cord-006870-f5w6fw6q 3872 18 3 3 CD cord-006870-f5w6fw6q 3872 19 are be VBP cord-006870-f5w6fw6q 3872 20 in in IN cord-006870-f5w6fw6q 3872 21 the the DT cord-006870-f5w6fw6q 3872 22 process process NN cord-006870-f5w6fw6q 3872 23 . . . cord-006870-f5w6fw6q 3873 1 Every every DT cord-006870-f5w6fw6q 3873 2 application application NN cord-006870-f5w6fw6q 3873 3 has have VBZ cord-006870-f5w6fw6q 3873 4 been be VBN cord-006870-f5w6fw6q 3873 5 prepared prepare VBN cord-006870-f5w6fw6q 3873 6 and and CC cord-006870-f5w6fw6q 3873 7 submitted submit VBN cord-006870-f5w6fw6q 3873 8 for for IN cord-006870-f5w6fw6q 3873 9 peer peer NN cord-006870-f5w6fw6q 3873 10 review review NN cord-006870-f5w6fw6q 3873 11 within within IN cord-006870-f5w6fw6q 3873 12 3 3 CD cord-006870-f5w6fw6q 3873 13 months month NNS cord-006870-f5w6fw6q 3873 14 of of IN cord-006870-f5w6fw6q 3873 15 the the DT cord-006870-f5w6fw6q 3873 16 NINDS NINDS NNP cord-006870-f5w6fw6q 3873 17 permission permission NN cord-006870-f5w6fw6q 3873 18 . . . cord-006870-f5w6fw6q 3874 1 Two two CD cord-006870-f5w6fw6q 3874 2 * * NFP cord-006870-f5w6fw6q 3874 3 funded fund VBD cord-006870-f5w6fw6q 3874 4 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3874 5 trials trial NNS cord-006870-f5w6fw6q 3874 6 are be VBP cord-006870-f5w6fw6q 3874 7 now now RB cord-006870-f5w6fw6q 3874 8 underway underway JJ cord-006870-f5w6fw6q 3874 9 with with IN cord-006870-f5w6fw6q 3874 10 brisk brisk JJ cord-006870-f5w6fw6q 3874 11 enrollment enrollment NN cord-006870-f5w6fw6q 3874 12 rates rate NNS cord-006870-f5w6fw6q 3874 13 , , , cord-006870-f5w6fw6q 3874 14 and and CC cord-006870-f5w6fw6q 3874 15 another another DT cord-006870-f5w6fw6q 3874 16 is be VBZ cord-006870-f5w6fw6q 3874 17 awaiting await VBG cord-006870-f5w6fw6q 3874 18 study study NN cord-006870-f5w6fw6q 3874 19 initiation initiation NN cord-006870-f5w6fw6q 3874 20 . . . cord-006870-f5w6fw6q 3875 1 ( ( -LRB- cord-006870-f5w6fw6q 3876 1 * * NFP cord-006870-f5w6fw6q 3876 2 As as IN cord-006870-f5w6fw6q 3876 3 of of IN cord-006870-f5w6fw6q 3876 4 abstract abstract JJ cord-006870-f5w6fw6q 3876 5 submission submission NN cord-006870-f5w6fw6q 3876 6 date date NN cord-006870-f5w6fw6q 3876 7 ) ) -RRB- cord-006870-f5w6fw6q 3877 1 The the DT cord-006870-f5w6fw6q 3877 2 NIH NIH NNP cord-006870-f5w6fw6q 3877 3 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3877 4 has have VBZ cord-006870-f5w6fw6q 3877 5 become become VBN cord-006870-f5w6fw6q 3877 6 a a DT cord-006870-f5w6fw6q 3877 7 stable stable JJ cord-006870-f5w6fw6q 3877 8 infrastructure infrastructure NN cord-006870-f5w6fw6q 3877 9 and and CC cord-006870-f5w6fw6q 3877 10 offers offer VBZ cord-006870-f5w6fw6q 3877 11 several several JJ cord-006870-f5w6fw6q 3877 12 distinct distinct JJ cord-006870-f5w6fw6q 3877 13 advantages advantage NNS cord-006870-f5w6fw6q 3877 14 to to IN cord-006870-f5w6fw6q 3877 15 developing develop VBG cord-006870-f5w6fw6q 3877 16 competitive competitive JJ cord-006870-f5w6fw6q 3877 17 clinical clinical JJ cord-006870-f5w6fw6q 3877 18 trial trial NN cord-006870-f5w6fw6q 3877 19 proposals proposal NNS cord-006870-f5w6fw6q 3877 20 , , , cord-006870-f5w6fw6q 3877 21 including include VBG cord-006870-f5w6fw6q 3877 22 scientific scientific JJ cord-006870-f5w6fw6q 3877 23 input input NN cord-006870-f5w6fw6q 3877 24 from from IN cord-006870-f5w6fw6q 3877 25 the the DT cord-006870-f5w6fw6q 3877 26 StrokeNet StrokeNet NNP cord-006870-f5w6fw6q 3877 27 Working Working NNP cord-006870-f5w6fw6q 3877 28 Groups Groups NNPS cord-006870-f5w6fw6q 3877 29 , , , cord-006870-f5w6fw6q 3877 30 comprehensive comprehensive JJ cord-006870-f5w6fw6q 3877 31 feasibility feasibility NN cord-006870-f5w6fw6q 3877 32 assessments assessment NNS cord-006870-f5w6fw6q 3877 33 ( ( -LRB- cord-006870-f5w6fw6q 3877 34 including include VBG cord-006870-f5w6fw6q 3877 35 site site NN cord-006870-f5w6fw6q 3877 36 enthusiasm enthusiasm NN cord-006870-f5w6fw6q 3877 37 and and CC cord-006870-f5w6fw6q 3877 38 patient patient JJ cord-006870-f5w6fw6q 3877 39 availability availability NN cord-006870-f5w6fw6q 3877 40 ) ) -RRB- cord-006870-f5w6fw6q 3877 41 , , , cord-006870-f5w6fw6q 3877 42 assistance assistance NN cord-006870-f5w6fw6q 3877 43 with with IN cord-006870-f5w6fw6q 3877 44 grant grant NN cord-006870-f5w6fw6q 3877 45 budgeting budgeting NN cord-006870-f5w6fw6q 3877 46 , , , cord-006870-f5w6fw6q 3877 47 and and CC cord-006870-f5w6fw6q 3877 48 other other JJ cord-006870-f5w6fw6q 3877 49 requirements requirement NNS cord-006870-f5w6fw6q 3877 50 for for IN cord-006870-f5w6fw6q 3877 51 grant grant NN cord-006870-f5w6fw6q 3877 52 submission submission NN cord-006870-f5w6fw6q 3877 53 that that WDT cord-006870-f5w6fw6q 3877 54 are be VBP cord-006870-f5w6fw6q 3877 55 likely likely JJ cord-006870-f5w6fw6q 3877 56 to to TO cord-006870-f5w6fw6q 3877 57 help help VB cord-006870-f5w6fw6q 3877 58 refine refine VB cord-006870-f5w6fw6q 3877 59 and and CC cord-006870-f5w6fw6q 3877 60 improve improve VB cord-006870-f5w6fw6q 3877 61 the the DT cord-006870-f5w6fw6q 3877 62 application application NN cord-006870-f5w6fw6q 3877 63 . . . cord-006870-f5w6fw6q 3878 1 The the DT cord-006870-f5w6fw6q 3878 2 Modified Modified NNP cord-006870-f5w6fw6q 3878 3 Early Early NNP cord-006870-f5w6fw6q 3878 4 Warning warning NN cord-006870-f5w6fw6q 3878 5 Score score NN cord-006870-f5w6fw6q 3878 6 ( ( -LRB- cord-006870-f5w6fw6q 3878 7 MEWS MEWS NNP cord-006870-f5w6fw6q 3878 8 ) ) -RRB- cord-006870-f5w6fw6q 3878 9 is be VBZ cord-006870-f5w6fw6q 3878 10 a a DT cord-006870-f5w6fw6q 3878 11 physiological physiological JJ cord-006870-f5w6fw6q 3878 12 scoring scoring NN cord-006870-f5w6fw6q 3878 13 system system NN cord-006870-f5w6fw6q 3878 14 , , , cord-006870-f5w6fw6q 3878 15 validated validate VBN cord-006870-f5w6fw6q 3878 16 in in IN cord-006870-f5w6fw6q 3878 17 adult adult NN cord-006870-f5w6fw6q 3878 18 medicalsought medicalsought NNP cord-006870-f5w6fw6q 3878 19 to to TO cord-006870-f5w6fw6q 3878 20 determine determine VB cord-006870-f5w6fw6q 3878 21 the the DT cord-006870-f5w6fw6q 3878 22 value value NN cord-006870-f5w6fw6q 3878 23 of of IN cord-006870-f5w6fw6q 3878 24 MEWS MEWS NNP cord-006870-f5w6fw6q 3878 25 to to TO cord-006870-f5w6fw6q 3878 26 identify identify VB cord-006870-f5w6fw6q 3878 27 clinical clinical JJ cord-006870-f5w6fw6q 3878 28 deterioration deterioration NN cord-006870-f5w6fw6q 3878 29 or or CC cord-006870-f5w6fw6q 3878 30 occurrence occurrence NN cord-006870-f5w6fw6q 3878 31 of of IN cord-006870-f5w6fw6q 3878 32 sepsis sepsis NN cord-006870-f5w6fw6q 3878 33 in in IN cord-006870-f5w6fw6q 3878 34 neuroICU neuroICU NNP cord-006870-f5w6fw6q 3878 35 patients patient NNS cord-006870-f5w6fw6q 3878 36 . . . cord-006870-f5w6fw6q 3879 1 We -PRON- PRP cord-006870-f5w6fw6q 3879 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 3879 3 reviewed review VBD cord-006870-f5w6fw6q 3879 4 all all DT cord-006870-f5w6fw6q 3879 5 patients patient NNS cord-006870-f5w6fw6q 3879 6 admitted admit VBN cord-006870-f5w6fw6q 3879 7 to to IN cord-006870-f5w6fw6q 3879 8 the the DT cord-006870-f5w6fw6q 3879 9 neurological neurological JJ cord-006870-f5w6fw6q 3879 10 intermediate intermediate JJ cord-006870-f5w6fw6q 3879 11 care care NN cord-006870-f5w6fw6q 3879 12 unit unit NN cord-006870-f5w6fw6q 3879 13 ( ( -LRB- cord-006870-f5w6fw6q 3879 14 IMC IMC NNP cord-006870-f5w6fw6q 3879 15 ) ) -RRB- cord-006870-f5w6fw6q 3879 16 or or CC cord-006870-f5w6fw6q 3879 17 neuroICU neuroicu NN cord-006870-f5w6fw6q 3879 18 of of IN cord-006870-f5w6fw6q 3879 19 a a DT cord-006870-f5w6fw6q 3879 20 large large JJ cord-006870-f5w6fw6q 3879 21 tertiary tertiary JJ cord-006870-f5w6fw6q 3879 22 care care NN cord-006870-f5w6fw6q 3879 23 center center NN cord-006870-f5w6fw6q 3879 24 from from IN cord-006870-f5w6fw6q 3879 25 7/2015presentation 7/2015presentation NNP cord-006870-f5w6fw6q 3879 26 / / SYM cord-006870-f5w6fw6q 3879 27 during during IN cord-006870-f5w6fw6q 3879 28 admission admission NN cord-006870-f5w6fw6q 3879 29 . . . cord-006870-f5w6fw6q 3880 1 Baseline baseline JJ cord-006870-f5w6fw6q 3880 2 characteristics characteristic NNS cord-006870-f5w6fw6q 3880 3 , , , cord-006870-f5w6fw6q 3880 4 diagnoses diagnosis NNS cord-006870-f5w6fw6q 3880 5 , , , cord-006870-f5w6fw6q 3880 6 physiologic physiologic JJ cord-006870-f5w6fw6q 3880 7 parameters parameter NNS cord-006870-f5w6fw6q 3880 8 , , , cord-006870-f5w6fw6q 3880 9 infections infection NNS cord-006870-f5w6fw6q 3880 10 , , , cord-006870-f5w6fw6q 3880 11 treatment treatment NN cord-006870-f5w6fw6q 3880 12 with with IN cord-006870-f5w6fw6q 3880 13 antibiotics antibiotic NNS cord-006870-f5w6fw6q 3880 14 , , , cord-006870-f5w6fw6q 3880 15 neurological neurological JJ cord-006870-f5w6fw6q 3880 16 worsening worsening NN cord-006870-f5w6fw6q 3880 17 and and CC cord-006870-f5w6fw6q 3880 18 mortality mortality NN cord-006870-f5w6fw6q 3880 19 were be VBD cord-006870-f5w6fw6q 3880 20 abstracted abstract VBN cord-006870-f5w6fw6q 3880 21 from from IN cord-006870-f5w6fw6q 3880 22 the the DT cord-006870-f5w6fw6q 3880 23 electronic electronic JJ cord-006870-f5w6fw6q 3880 24 medical medical JJ cord-006870-f5w6fw6q 3880 25 record record NN cord-006870-f5w6fw6q 3880 26 . . . cord-006870-f5w6fw6q 3881 1 Outcomes outcome NNS cord-006870-f5w6fw6q 3881 2 were be VBD cord-006870-f5w6fw6q 3881 3 defined define VBN cord-006870-f5w6fw6q 3881 4 as as IN cord-006870-f5w6fw6q 3881 5 escalation escalation NN cord-006870-f5w6fw6q 3881 6 of of IN cord-006870-f5w6fw6q 3881 7 care care NN cord-006870-f5w6fw6q 3881 8 and and CC cord-006870-f5w6fw6q 3881 9 discovery discovery NN cord-006870-f5w6fw6q 3881 10 of of IN cord-006870-f5w6fw6q 3881 11 a a DT cord-006870-f5w6fw6q 3881 12 new new JJ cord-006870-f5w6fw6q 3881 13 infection infection NN cord-006870-f5w6fw6q 3881 14 or or CC cord-006870-f5w6fw6q 3881 15 sepsis sepsis NN cord-006870-f5w6fw6q 3881 16 . . . cord-006870-f5w6fw6q 3882 1 Of of IN cord-006870-f5w6fw6q 3882 2 2556 2556 CD cord-006870-f5w6fw6q 3882 3 p p NN cord-006870-f5w6fw6q 3882 4 were be VBD cord-006870-f5w6fw6q 3882 5 male male JJ cord-006870-f5w6fw6q 3882 6 . . . cord-006870-f5w6fw6q 3883 1 62 62 CD cord-006870-f5w6fw6q 3883 2 % % NN cord-006870-f5w6fw6q 3883 3 were be VBD cord-006870-f5w6fw6q 3883 4 intubated intubate VBN cord-006870-f5w6fw6q 3883 5 , , , cord-006870-f5w6fw6q 3883 6 and and CC cord-006870-f5w6fw6q 3883 7 in in IN cord-006870-f5w6fw6q 3883 8 - - HYPH cord-006870-f5w6fw6q 3883 9 hospital hospital NN cord-006870-f5w6fw6q 3883 10 mortality mortality NN cord-006870-f5w6fw6q 3883 11 was be VBD cord-006870-f5w6fw6q 3883 12 22 22 CD cord-006870-f5w6fw6q 3883 13 % % NN cord-006870-f5w6fw6q 3883 14 ( ( -LRB- cord-006870-f5w6fw6q 3883 15 versus versus IN cord-006870-f5w6fw6q 3883 16 9 9 CD cord-006870-f5w6fw6q 3883 17 % % NN cord-006870-f5w6fw6q 3883 18 for for IN cord-006870-f5w6fw6q 3883 19 all all DT cord-006870-f5w6fw6q 3883 20 admissions admission NNS cord-006870-f5w6fw6q 3883 21 ) ) -RRB- cord-006870-f5w6fw6q 3883 22 . . . cord-006870-f5w6fw6q 3884 1 182 182 CD cord-006870-f5w6fw6q 3884 2 ( ( -LRB- cord-006870-f5w6fw6q 3884 3 40 40 CD cord-006870-f5w6fw6q 3884 4 % % NN cord-006870-f5w6fw6q 3884 5 ) ) -RRB- cord-006870-f5w6fw6q 3884 6 were be VBD cord-006870-f5w6fw6q 3884 7 already already RB cord-006870-f5w6fw6q 3884 8 treated treat VBN cord-006870-f5w6fw6q 3884 9 with with IN cord-006870-f5w6fw6q 3884 10 antibiotics antibiotic NNS cord-006870-f5w6fw6q 3884 11 for for IN cord-006870-f5w6fw6q 3884 12 a a DT cord-006870-f5w6fw6q 3884 13 known know VBN cord-006870-f5w6fw6q 3884 14 infec infec IN cord-006870-f5w6fw6q 3884 15 diagnosed diagnose VBN cord-006870-f5w6fw6q 3884 16 in in IN cord-006870-f5w6fw6q 3884 17 19 19 CD cord-006870-f5w6fw6q 3884 18 % % NN cord-006870-f5w6fw6q 3884 19 . . . cord-006870-f5w6fw6q 3885 1 In in IN cord-006870-f5w6fw6q 3885 2 reaction reaction NN cord-006870-f5w6fw6q 3885 3 to to IN cord-006870-f5w6fw6q 3885 4 the the DT cord-006870-f5w6fw6q 3885 5 elevated elevated JJ cord-006870-f5w6fw6q 3885 6 MEWS MEWS NNP cord-006870-f5w6fw6q 3885 7 score score NN cord-006870-f5w6fw6q 3885 8 , , , cord-006870-f5w6fw6q 3885 9 antibiotics antibiotic NNS cord-006870-f5w6fw6q 3885 10 were be VBD cord-006870-f5w6fw6q 3885 11 added add VBN cord-006870-f5w6fw6q 3885 12 or or CC cord-006870-f5w6fw6q 3885 13 broadened broaden VBN cord-006870-f5w6fw6q 3885 14 in in IN cord-006870-f5w6fw6q 3885 15 22 22 CD cord-006870-f5w6fw6q 3885 16 % % NN cord-006870-f5w6fw6q 3885 17 , , , cord-006870-f5w6fw6q 3885 18 and and CC cord-006870-f5w6fw6q 3885 19 level level NN cord-006870-f5w6fw6q 3885 20 of of IN cord-006870-f5w6fw6q 3885 21 care care NN cord-006870-f5w6fw6q 3885 22 was be VBD cord-006870-f5w6fw6q 3885 23 escalated escalate VBN cord-006870-f5w6fw6q 3885 24 in in IN cord-006870-f5w6fw6q 3885 25 2.7 2.7 CD cord-006870-f5w6fw6q 3885 26 % % NN cord-006870-f5w6fw6q 3885 27 from from IN cord-006870-f5w6fw6q 3885 28 IMC IMC NNP cord-006870-f5w6fw6q 3885 29 to to IN cord-006870-f5w6fw6q 3885 30 ICU ICU NNP cord-006870-f5w6fw6q 3885 31 . . . cord-006870-f5w6fw6q 3886 1 In in IN cord-006870-f5w6fw6q 3886 2 18.2 18.2 CD cord-006870-f5w6fw6q 3886 3 % % NN cord-006870-f5w6fw6q 3886 4 , , , cord-006870-f5w6fw6q 3886 5 there there EX cord-006870-f5w6fw6q 3886 6 was be VBD cord-006870-f5w6fw6q 3886 7 neurological neurological JJ cord-006870-f5w6fw6q 3886 8 worsening worsen VBG cord-006870-f5w6fw6q 3886 9 , , , cord-006870-f5w6fw6q 3886 10 most most RBS cord-006870-f5w6fw6q 3886 11 frequently frequently RB cord-006870-f5w6fw6q 3886 12 associated associate VBN cord-006870-f5w6fw6q 3886 13 with with IN cord-006870-f5w6fw6q 3886 14 increasing increase VBG cord-006870-f5w6fw6q 3886 15 cerebral cerebral JJ cord-006870-f5w6fw6q 3886 16 edema edema NN cord-006870-f5w6fw6q 3886 17 ( ( -LRB- cord-006870-f5w6fw6q 3886 18 34 34 CD cord-006870-f5w6fw6q 3886 19 % % NN cord-006870-f5w6fw6q 3886 20 ) ) -RRB- cord-006870-f5w6fw6q 3886 21 and and CC cord-006870-f5w6fw6q 3886 22 midline midline JJ cord-006870-f5w6fw6q 3886 23 shift shift NN cord-006870-f5w6fw6q 3886 24 / / SYM cord-006870-f5w6fw6q 3886 25 herniation herniation NN cord-006870-f5w6fw6q 3886 26 ( ( -LRB- cord-006870-f5w6fw6q 3886 27 18 18 CD cord-006870-f5w6fw6q 3886 28 % % NN cord-006870-f5w6fw6q 3886 29 ) ) -RRB- cord-006870-f5w6fw6q 3886 30 . . . cord-006870-f5w6fw6q 3887 1 The the DT cord-006870-f5w6fw6q 3887 2 MEWS MEWS NNP cord-006870-f5w6fw6q 3887 3 score score NN cord-006870-f5w6fw6q 3887 4 is be VBZ cord-006870-f5w6fw6q 3887 5 not not RB cord-006870-f5w6fw6q 3887 6 a a DT cord-006870-f5w6fw6q 3887 7 valuable valuable JJ cord-006870-f5w6fw6q 3887 8 screening screening NN cord-006870-f5w6fw6q 3887 9 tool tool NN cord-006870-f5w6fw6q 3887 10 in in IN cord-006870-f5w6fw6q 3887 11 the the DT cord-006870-f5w6fw6q 3887 12 neuroICU neuroICU NNP cord-006870-f5w6fw6q 3887 13 population population NN cord-006870-f5w6fw6q 3887 14 . . . cord-006870-f5w6fw6q 3888 1 It -PRON- PRP cord-006870-f5w6fw6q 3888 2 preferentially preferentially RB cord-006870-f5w6fw6q 3888 3 was be VBD cord-006870-f5w6fw6q 3888 4 triggered trigger VBN cord-006870-f5w6fw6q 3888 5 in in IN cord-006870-f5w6fw6q 3888 6 known know VBN cord-006870-f5w6fw6q 3888 7 high high JJ cord-006870-f5w6fw6q 3888 8 acuity acuity NN cord-006870-f5w6fw6q 3888 9 patients patient NNS cord-006870-f5w6fw6q 3888 10 with with IN cord-006870-f5w6fw6q 3888 11 ongoing ongoing JJ cord-006870-f5w6fw6q 3888 12 or or CC cord-006870-f5w6fw6q 3888 13 present present JJ cord-006870-f5w6fw6q 3888 14 infections infection NNS cord-006870-f5w6fw6q 3888 15 with with IN cord-006870-f5w6fw6q 3888 16 no no DT cord-006870-f5w6fw6q 3888 17 change change NN cord-006870-f5w6fw6q 3888 18 of of IN cord-006870-f5w6fw6q 3888 19 management management NN cord-006870-f5w6fw6q 3888 20 in in IN cord-006870-f5w6fw6q 3888 21 the the DT cord-006870-f5w6fw6q 3888 22 majority majority NN cord-006870-f5w6fw6q 3888 23 of of IN cord-006870-f5w6fw6q 3888 24 patients patient NNS cord-006870-f5w6fw6q 3888 25 . . . cord-006870-f5w6fw6q 3889 1 While while IN cord-006870-f5w6fw6q 3889 2 associated associate VBN cord-006870-f5w6fw6q 3889 3 with with IN cord-006870-f5w6fw6q 3889 4 high high JJ cord-006870-f5w6fw6q 3889 5 mortality mortality NN cord-006870-f5w6fw6q 3889 6 , , , cord-006870-f5w6fw6q 3889 7 its -PRON- PRP$ cord-006870-f5w6fw6q 3889 8 ability ability NN cord-006870-f5w6fw6q 3889 9 to to TO cord-006870-f5w6fw6q 3889 10 indicate indicate VB cord-006870-f5w6fw6q 3889 11 new new JJ cord-006870-f5w6fw6q 3889 12 infections infection NNS cord-006870-f5w6fw6q 3889 13 or or CC cord-006870-f5w6fw6q 3889 14 sepsis sepsis NN cord-006870-f5w6fw6q 3889 15 was be VBD cord-006870-f5w6fw6q 3889 16 poor poor JJ cord-006870-f5w6fw6q 3889 17 . . . cord-006870-f5w6fw6q 3890 1 In in IN cord-006870-f5w6fw6q 3890 2 1 1 CD cord-006870-f5w6fw6q 3890 3 out out IN cord-006870-f5w6fw6q 3890 4 of of IN cord-006870-f5w6fw6q 3890 5 5 5 CD cord-006870-f5w6fw6q 3890 6 patients patient NNS cord-006870-f5w6fw6q 3890 7 , , , cord-006870-f5w6fw6q 3890 8 the the DT cord-006870-f5w6fw6q 3890 9 MEWS MEWS NNP cord-006870-f5w6fw6q 3890 10 score score NN cord-006870-f5w6fw6q 3890 11 was be VBD cord-006870-f5w6fw6q 3890 12 associated associate VBN cord-006870-f5w6fw6q 3890 13 with with IN cord-006870-f5w6fw6q 3890 14 neurological neurological JJ cord-006870-f5w6fw6q 3890 15 worsening worsen VBG cord-006870-f5w6fw6q 3890 16 known know VBN cord-006870-f5w6fw6q 3890 17 at at IN cord-006870-f5w6fw6q 3890 18 that that DT cord-006870-f5w6fw6q 3890 19 time time NN cord-006870-f5w6fw6q 3890 20 of of IN cord-006870-f5w6fw6q 3890 21 the the DT cord-006870-f5w6fw6q 3890 22 score score NN cord-006870-f5w6fw6q 3890 23 . . . cord-006870-f5w6fw6q 3891 1 Other other JJ cord-006870-f5w6fw6q 3891 2 screening screening NN cord-006870-f5w6fw6q 3891 3 tools tool NNS cord-006870-f5w6fw6q 3891 4 should should MD cord-006870-f5w6fw6q 3891 5 be be VB cord-006870-f5w6fw6q 3891 6 explored explore VBN cord-006870-f5w6fw6q 3891 7 for for IN cord-006870-f5w6fw6q 3891 8 early early JJ cord-006870-f5w6fw6q 3891 9 warning warning NN cord-006870-f5w6fw6q 3891 10 in in IN cord-006870-f5w6fw6q 3891 11 the the DT cord-006870-f5w6fw6q 3891 12 neuroICU neuroICU NNP cord-006870-f5w6fw6q 3891 13 . . . cord-006870-f5w6fw6q 3892 1 Introduction introduction NN cord-006870-f5w6fw6q 3892 2 : : : cord-006870-f5w6fw6q 3893 1 It -PRON- PRP cord-006870-f5w6fw6q 3893 2 is be VBZ cord-006870-f5w6fw6q 3893 3 challenging challenge VBG cord-006870-f5w6fw6q 3893 4 to to TO cord-006870-f5w6fw6q 3893 5 maintain maintain VB cord-006870-f5w6fw6q 3893 6 neurosciences neuroscience NNS cord-006870-f5w6fw6q 3893 7 critical critical JJ cord-006870-f5w6fw6q 3893 8 care care NN cord-006870-f5w6fw6q 3893 9 nursing nursing NN cord-006870-f5w6fw6q 3893 10 expertise expertise NN cord-006870-f5w6fw6q 3893 11 in in IN cord-006870-f5w6fw6q 3893 12 an an DT cord-006870-f5w6fw6q 3893 13 environment environment NN cord-006870-f5w6fw6q 3893 14 of of IN cord-006870-f5w6fw6q 3893 15 a a DT cord-006870-f5w6fw6q 3893 16 rapidly rapidly RB cord-006870-f5w6fw6q 3893 17 expanding expand VBG cord-006870-f5w6fw6q 3893 18 knowledge knowledge NN cord-006870-f5w6fw6q 3893 19 , , , cord-006870-f5w6fw6q 3893 20 changing change VBG cord-006870-f5w6fw6q 3893 21 evidence evidence NN cord-006870-f5w6fw6q 3893 22 - - HYPH cord-006870-f5w6fw6q 3893 23 based base VBN cord-006870-f5w6fw6q 3893 24 practices practice NNS cord-006870-f5w6fw6q 3893 25 and and CC cord-006870-f5w6fw6q 3893 26 technological technological JJ cord-006870-f5w6fw6q 3893 27 advancements advancement NNS cord-006870-f5w6fw6q 3893 28 . . . cord-006870-f5w6fw6q 3894 1 To to TO cord-006870-f5w6fw6q 3894 2 address address VB cord-006870-f5w6fw6q 3894 3 the the DT cord-006870-f5w6fw6q 3894 4 needs need NNS cord-006870-f5w6fw6q 3894 5 for for IN cord-006870-f5w6fw6q 3894 6 neuroscience neuroscience NN cord-006870-f5w6fw6q 3894 7 nursing nursing NN cord-006870-f5w6fw6q 3894 8 expertise expertise NN cord-006870-f5w6fw6q 3894 9 in in IN cord-006870-f5w6fw6q 3894 10 a a DT cord-006870-f5w6fw6q 3894 11 mixed mixed JJ cord-006870-f5w6fw6q 3894 12 Critical Critical NNP cord-006870-f5w6fw6q 3894 13 Care Care NNP cord-006870-f5w6fw6q 3894 14 Unit Unit NNP cord-006870-f5w6fw6q 3894 15 , , , cord-006870-f5w6fw6q 3894 16 our -PRON- PRP$ cord-006870-f5w6fw6q 3894 17 institution institution NN cord-006870-f5w6fw6q 3894 18 developed develop VBD cord-006870-f5w6fw6q 3894 19 a a DT cord-006870-f5w6fw6q 3894 20 core core NN cord-006870-f5w6fw6q 3894 21 group group NN cord-006870-f5w6fw6q 3894 22 of of IN cord-006870-f5w6fw6q 3894 23 nurses nurse NNS cord-006870-f5w6fw6q 3894 24 , , , cord-006870-f5w6fw6q 3894 25 known know VBN cord-006870-f5w6fw6q 3894 26 as as IN cord-006870-f5w6fw6q 3894 27 " " `` cord-006870-f5w6fw6q 3894 28 Neuro Neuro NNP cord-006870-f5w6fw6q 3894 29 Champions Champions NNPS cord-006870-f5w6fw6q 3894 30 " " '' cord-006870-f5w6fw6q 3894 31 , , , cord-006870-f5w6fw6q 3894 32 who who WP cord-006870-f5w6fw6q 3894 33 have have VBP cord-006870-f5w6fw6q 3894 34 additional additional JJ cord-006870-f5w6fw6q 3894 35 training training NN cord-006870-f5w6fw6q 3894 36 and and CC cord-006870-f5w6fw6q 3894 37 expertise expertise NN cord-006870-f5w6fw6q 3894 38 in in IN cord-006870-f5w6fw6q 3894 39 neurocritical neurocritical NNP cord-006870-f5w6fw6q 3894 40 care care NN cord-006870-f5w6fw6q 3894 41 . . . cord-006870-f5w6fw6q 3895 1 Methods method NNS cord-006870-f5w6fw6q 3895 2 : : : cord-006870-f5w6fw6q 3896 1 Nursing nursing NN cord-006870-f5w6fw6q 3896 2 participation participation NN cord-006870-f5w6fw6q 3896 3 was be VBD cord-006870-f5w6fw6q 3896 4 voluntary voluntary JJ cord-006870-f5w6fw6q 3896 5 and and CC cord-006870-f5w6fw6q 3896 6 recruitment recruitment NN cord-006870-f5w6fw6q 3896 7 was be VBD cord-006870-f5w6fw6q 3896 8 via via IN cord-006870-f5w6fw6q 3896 9 unit unit NN cord-006870-f5w6fw6q 3896 10 - - HYPH cord-006870-f5w6fw6q 3896 11 wide wide JJ cord-006870-f5w6fw6q 3896 12 announcements announcement NNS cord-006870-f5w6fw6q 3896 13 . . . cord-006870-f5w6fw6q 3897 1 The the DT cord-006870-f5w6fw6q 3897 2 goal goal NN cord-006870-f5w6fw6q 3897 3 was be VBD cord-006870-f5w6fw6q 3897 4 to to TO cord-006870-f5w6fw6q 3897 5 improve improve VB cord-006870-f5w6fw6q 3897 6 patient patient JJ cord-006870-f5w6fw6q 3897 7 care care NN cord-006870-f5w6fw6q 3897 8 by by IN cord-006870-f5w6fw6q 3897 9 developing develop VBG cord-006870-f5w6fw6q 3897 10 a a DT cord-006870-f5w6fw6q 3897 11 core core NN cord-006870-f5w6fw6q 3897 12 group group NN cord-006870-f5w6fw6q 3897 13 of of IN cord-006870-f5w6fw6q 3897 14 nurses nurse NNS cord-006870-f5w6fw6q 3897 15 who who WP cord-006870-f5w6fw6q 3897 16 serve serve VBP cord-006870-f5w6fw6q 3897 17 as as IN cord-006870-f5w6fw6q 3897 18 resources resource NNS cord-006870-f5w6fw6q 3897 19 and and CC cord-006870-f5w6fw6q 3897 20 educators educator NNS cord-006870-f5w6fw6q 3897 21 for for IN cord-006870-f5w6fw6q 3897 22 all all DT cord-006870-f5w6fw6q 3897 23 things thing NNS cord-006870-f5w6fw6q 3897 24 neurosciences neuroscience NNS cord-006870-f5w6fw6q 3897 25 related relate VBN cord-006870-f5w6fw6q 3897 26 . . . cord-006870-f5w6fw6q 3898 1 To to TO cord-006870-f5w6fw6q 3898 2 develop develop VB cord-006870-f5w6fw6q 3898 3 content content NN cord-006870-f5w6fw6q 3898 4 expertise expertise NN cord-006870-f5w6fw6q 3898 5 , , , cord-006870-f5w6fw6q 3898 6 the the DT cord-006870-f5w6fw6q 3898 7 nurses nurse NNS cord-006870-f5w6fw6q 3898 8 initially initially RB cord-006870-f5w6fw6q 3898 9 completed complete VBD cord-006870-f5w6fw6q 3898 10 a a DT cord-006870-f5w6fw6q 3898 11 set set VBN cord-006870-f5w6fw6q 3898 12 curriculum curriculum NN cord-006870-f5w6fw6q 3898 13 including include VBG cord-006870-f5w6fw6q 3898 14 : : : cord-006870-f5w6fw6q 3898 15 neuro neuro NNP cord-006870-f5w6fw6q 3898 16 anatomy anatomy NN cord-006870-f5w6fw6q 3898 17 and and CC cord-006870-f5w6fw6q 3898 18 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 3898 19 , , , cord-006870-f5w6fw6q 3898 20 cerebral cerebral JJ cord-006870-f5w6fw6q 3898 21 hemodynamics hemodynamic NNS cord-006870-f5w6fw6q 3898 22 and and CC cord-006870-f5w6fw6q 3898 23 multimodal multimodal NN cord-006870-f5w6fw6q 3898 24 monitoring monitoring NN cord-006870-f5w6fw6q 3898 25 , , , cord-006870-f5w6fw6q 3898 26 pupillometry pupillometry NNP cord-006870-f5w6fw6q 3898 27 , , , cord-006870-f5w6fw6q 3898 28 EEG EEG NNP cord-006870-f5w6fw6q 3898 29 interpretation interpretation NN cord-006870-f5w6fw6q 3898 30 , , , cord-006870-f5w6fw6q 3898 31 temperature temperature NN cord-006870-f5w6fw6q 3898 32 management management NN cord-006870-f5w6fw6q 3898 33 , , , cord-006870-f5w6fw6q 3898 34 EVDs EVDs NNP cord-006870-f5w6fw6q 3898 35 , , , cord-006870-f5w6fw6q 3898 36 and and CC cord-006870-f5w6fw6q 3898 37 quality quality NN cord-006870-f5w6fw6q 3898 38 indicators indicator NNS cord-006870-f5w6fw6q 3898 39 . . . cord-006870-f5w6fw6q 3899 1 Bi bi JJ cord-006870-f5w6fw6q 3899 2 - - JJ cord-006870-f5w6fw6q 3899 3 monthly monthly JJ cord-006870-f5w6fw6q 3899 4 meetings meeting NNS cord-006870-f5w6fw6q 3899 5 continued continue VBD cord-006870-f5w6fw6q 3899 6 ongoing ongoing JJ cord-006870-f5w6fw6q 3899 7 education education NN cord-006870-f5w6fw6q 3899 8 , , , cord-006870-f5w6fw6q 3899 9 with with IN cord-006870-f5w6fw6q 3899 10 content content NN cord-006870-f5w6fw6q 3899 11 including include VBG cord-006870-f5w6fw6q 3899 12 clinical clinical JJ cord-006870-f5w6fw6q 3899 13 case case NN cord-006870-f5w6fw6q 3899 14 studies study NNS cord-006870-f5w6fw6q 3899 15 and and CC cord-006870-f5w6fw6q 3899 16 review review NN cord-006870-f5w6fw6q 3899 17 of of IN cord-006870-f5w6fw6q 3899 18 processes process NNS cord-006870-f5w6fw6q 3899 19 and and CC cord-006870-f5w6fw6q 3899 20 protocols protocol NNS cord-006870-f5w6fw6q 3899 21 . . . cord-006870-f5w6fw6q 3900 1 Additionally additionally RB cord-006870-f5w6fw6q 3900 2 , , , cord-006870-f5w6fw6q 3900 3 6 6 CD cord-006870-f5w6fw6q 3900 4 beds bed NNS cord-006870-f5w6fw6q 3900 5 staffed staff VBN cord-006870-f5w6fw6q 3900 6 by by IN cord-006870-f5w6fw6q 3900 7 Neuro Neuro NNP cord-006870-f5w6fw6q 3900 8 Champions Champions NNPS cord-006870-f5w6fw6q 3900 9 were be VBD cord-006870-f5w6fw6q 3900 10 designated designate VBN cord-006870-f5w6fw6q 3900 11 as as IN cord-006870-f5w6fw6q 3900 12 Critical Critical NNP cord-006870-f5w6fw6q 3900 13 Neurological Neurological NNP cord-006870-f5w6fw6q 3900 14 Care Care NNP cord-006870-f5w6fw6q 3900 15 Unit Unit NNP cord-006870-f5w6fw6q 3900 16 ( ( -LRB- cord-006870-f5w6fw6q 3900 17 " " `` cord-006870-f5w6fw6q 3900 18 CNCU CNCU NNP cord-006870-f5w6fw6q 3900 19 " " '' cord-006870-f5w6fw6q 3900 20 ) ) -RRB- cord-006870-f5w6fw6q 3900 21 beds bed NNS cord-006870-f5w6fw6q 3900 22 to to TO cord-006870-f5w6fw6q 3900 23 co co VB cord-006870-f5w6fw6q 3900 24 - - VB cord-006870-f5w6fw6q 3900 25 localize localize VB cord-006870-f5w6fw6q 3900 26 the the DT cord-006870-f5w6fw6q 3900 27 highest high JJS cord-006870-f5w6fw6q 3900 28 acuity acuity NN cord-006870-f5w6fw6q 3900 29 neurosciences neuroscience NNS cord-006870-f5w6fw6q 3900 30 patients patient NNS cord-006870-f5w6fw6q 3900 31 . . . cord-006870-f5w6fw6q 3901 1 The the DT cord-006870-f5w6fw6q 3901 2 Neuro Neuro NNP cord-006870-f5w6fw6q 3901 3 Champions Champions NNPS cord-006870-f5w6fw6q 3901 4 are be VBP cord-006870-f5w6fw6q 3901 5 responsible responsible JJ cord-006870-f5w6fw6q 3901 6 for for IN cord-006870-f5w6fw6q 3901 7 educating educate VBG cord-006870-f5w6fw6q 3901 8 and and CC cord-006870-f5w6fw6q 3901 9 sharing share VBG cord-006870-f5w6fw6q 3901 10 neuro neuro NNP cord-006870-f5w6fw6q 3901 11 related related JJ cord-006870-f5w6fw6q 3901 12 practices practice NNS cord-006870-f5w6fw6q 3901 13 with with IN cord-006870-f5w6fw6q 3901 14 the the DT cord-006870-f5w6fw6q 3901 15 entire entire JJ cord-006870-f5w6fw6q 3901 16 ICU ICU NNP cord-006870-f5w6fw6q 3901 17 nursing nursing NN cord-006870-f5w6fw6q 3901 18 staff staff NN cord-006870-f5w6fw6q 3901 19 . . . cord-006870-f5w6fw6q 3902 1 Results result NNS cord-006870-f5w6fw6q 3902 2 : : : cord-006870-f5w6fw6q 3903 1 As as IN cord-006870-f5w6fw6q 3903 2 a a DT cord-006870-f5w6fw6q 3903 3 result result NN cord-006870-f5w6fw6q 3903 4 of of IN cord-006870-f5w6fw6q 3903 5 the the DT cord-006870-f5w6fw6q 3903 6 implementation implementation NN cord-006870-f5w6fw6q 3903 7 of of IN cord-006870-f5w6fw6q 3903 8 the the DT cord-006870-f5w6fw6q 3903 9 Neuro Neuro NNP cord-006870-f5w6fw6q 3903 10 Champion Champion NNP cord-006870-f5w6fw6q 3903 11 role role NN cord-006870-f5w6fw6q 3903 12 , , , cord-006870-f5w6fw6q 3903 13 our -PRON- PRP$ cord-006870-f5w6fw6q 3903 14 ICU ICU NNP cord-006870-f5w6fw6q 3903 15 has have VBZ cord-006870-f5w6fw6q 3903 16 benefited benefit VBN cord-006870-f5w6fw6q 3903 17 from from IN cord-006870-f5w6fw6q 3903 18 : : : cord-006870-f5w6fw6q 3903 19 1 1 LS cord-006870-f5w6fw6q 3903 20 ) ) -RRB- cord-006870-f5w6fw6q 3903 21 dedicated dedicated JJ cord-006870-f5w6fw6q 3903 22 co co JJ cord-006870-f5w6fw6q 3903 23 - - JJ cord-006870-f5w6fw6q 3903 24 localized localized JJ cord-006870-f5w6fw6q 3903 25 beds bed NNS cord-006870-f5w6fw6q 3903 26 for for IN cord-006870-f5w6fw6q 3903 27 the the DT cord-006870-f5w6fw6q 3903 28 highest high JJS cord-006870-f5w6fw6q 3903 29 acuity acuity NNP cord-006870-f5w6fw6q 3903 30 neuro neuro NNP cord-006870-f5w6fw6q 3903 31 patients patient NNS cord-006870-f5w6fw6q 3903 32 ; ; : cord-006870-f5w6fw6q 3903 33 2 2 LS cord-006870-f5w6fw6q 3903 34 ) ) -RRB- cord-006870-f5w6fw6q 3903 35 increased increase VBN cord-006870-f5w6fw6q 3903 36 number number NN cord-006870-f5w6fw6q 3903 37 of of IN cord-006870-f5w6fw6q 3903 38 ENLS enl NNS cord-006870-f5w6fw6q 3903 39 certified certify VBN cord-006870-f5w6fw6q 3903 40 nurses nurse NNS cord-006870-f5w6fw6q 3903 41 ; ; : cord-006870-f5w6fw6q 3903 42 3 3 LS cord-006870-f5w6fw6q 3903 43 ) ) -RRB- cord-006870-f5w6fw6q 3903 44 improved improve VBN cord-006870-f5w6fw6q 3903 45 collaboration collaboration NN cord-006870-f5w6fw6q 3903 46 between between IN cord-006870-f5w6fw6q 3903 47 the the DT cord-006870-f5w6fw6q 3903 48 medical medical JJ cord-006870-f5w6fw6q 3903 49 team team NN cord-006870-f5w6fw6q 3903 50 and and CC cord-006870-f5w6fw6q 3903 51 nurses nurse NNS cord-006870-f5w6fw6q 3903 52 ; ; : cord-006870-f5w6fw6q 3903 53 4 4 LS cord-006870-f5w6fw6q 3903 54 ) ) -RRB- cord-006870-f5w6fw6q 3903 55 promoting promote VBG cord-006870-f5w6fw6q 3903 56 care care NN cord-006870-f5w6fw6q 3903 57 uniformity uniformity NN cord-006870-f5w6fw6q 3903 58 to to TO cord-006870-f5w6fw6q 3903 59 maintain maintain VB cord-006870-f5w6fw6q 3903 60 Comprehensive Comprehensive NNP cord-006870-f5w6fw6q 3903 61 Stroke Stroke NNP cord-006870-f5w6fw6q 3903 62 Center Center NNP cord-006870-f5w6fw6q 3903 63 certification certification NN cord-006870-f5w6fw6q 3903 64 ; ; : cord-006870-f5w6fw6q 3903 65 5 5 LS cord-006870-f5w6fw6q 3903 66 ) ) -RRB- cord-006870-f5w6fw6q 3903 67 integration integration NN cord-006870-f5w6fw6q 3903 68 of of IN cord-006870-f5w6fw6q 3903 69 multimodal multimodal NN cord-006870-f5w6fw6q 3903 70 monitoring monitoring NN cord-006870-f5w6fw6q 3903 71 advancements advancement NNS cord-006870-f5w6fw6q 3903 72 , , , cord-006870-f5w6fw6q 3903 73 all all DT cord-006870-f5w6fw6q 3903 74 of of IN cord-006870-f5w6fw6q 3903 75 which which WDT cord-006870-f5w6fw6q 3903 76 supports support VBZ cord-006870-f5w6fw6q 3903 77 advances advance NNS cord-006870-f5w6fw6q 3903 78 in in IN cord-006870-f5w6fw6q 3903 79 patient patient JJ cord-006870-f5w6fw6q 3903 80 care care NN cord-006870-f5w6fw6q 3903 81 and and CC cord-006870-f5w6fw6q 3903 82 research research NN cord-006870-f5w6fw6q 3903 83 . . . cord-006870-f5w6fw6q 3904 1 Conclusions conclusion NNS cord-006870-f5w6fw6q 3904 2 : : : cord-006870-f5w6fw6q 3905 1 The the DT cord-006870-f5w6fw6q 3905 2 Neuro Neuro NNP cord-006870-f5w6fw6q 3905 3 Champion Champion NNP cord-006870-f5w6fw6q 3905 4 role role NN cord-006870-f5w6fw6q 3905 5 has have VBZ cord-006870-f5w6fw6q 3905 6 provided provide VBN cord-006870-f5w6fw6q 3905 7 a a DT cord-006870-f5w6fw6q 3905 8 platform platform NN cord-006870-f5w6fw6q 3905 9 for for IN cord-006870-f5w6fw6q 3905 10 neurosciences neuroscience NNS cord-006870-f5w6fw6q 3905 11 - - HYPH cord-006870-f5w6fw6q 3905 12 specific specific JJ cord-006870-f5w6fw6q 3905 13 nursing nursing NN cord-006870-f5w6fw6q 3905 14 expertise expertise NN cord-006870-f5w6fw6q 3905 15 in in IN cord-006870-f5w6fw6q 3905 16 a a DT cord-006870-f5w6fw6q 3905 17 mixed mixed JJ cord-006870-f5w6fw6q 3905 18 critical critical JJ cord-006870-f5w6fw6q 3905 19 care care NN cord-006870-f5w6fw6q 3905 20 unit unit NN cord-006870-f5w6fw6q 3905 21 and and CC cord-006870-f5w6fw6q 3905 22 has have VBZ cord-006870-f5w6fw6q 3905 23 facilitated facilitate VBN cord-006870-f5w6fw6q 3905 24 education education NN cord-006870-f5w6fw6q 3905 25 dissemination dissemination NN cord-006870-f5w6fw6q 3905 26 to to IN cord-006870-f5w6fw6q 3905 27 the the DT cord-006870-f5w6fw6q 3905 28 entire entire JJ cord-006870-f5w6fw6q 3905 29 staff staff NN cord-006870-f5w6fw6q 3905 30 via via IN cord-006870-f5w6fw6q 3905 31 a a DT cord-006870-f5w6fw6q 3905 32 core core NN cord-006870-f5w6fw6q 3905 33 group group NN cord-006870-f5w6fw6q 3905 34 of of IN cord-006870-f5w6fw6q 3905 35 nurses nurse NNS cord-006870-f5w6fw6q 3905 36 . . . cord-006870-f5w6fw6q 3906 1 This this DT cord-006870-f5w6fw6q 3906 2 expanded expand VBN cord-006870-f5w6fw6q 3906 3 knowledge knowledge NN cord-006870-f5w6fw6q 3906 4 has have VBZ cord-006870-f5w6fw6q 3906 5 improved improve VBN cord-006870-f5w6fw6q 3906 6 the the DT cord-006870-f5w6fw6q 3906 7 care care NN cord-006870-f5w6fw6q 3906 8 of of IN cord-006870-f5w6fw6q 3906 9 the the DT cord-006870-f5w6fw6q 3906 10 neurologically neurologically RB cord-006870-f5w6fw6q 3906 11 critically critically RB cord-006870-f5w6fw6q 3906 12 ill ill JJ cord-006870-f5w6fw6q 3906 13 patients patient NNS cord-006870-f5w6fw6q 3906 14 . . . cord-006870-f5w6fw6q 3907 1 The the DT cord-006870-f5w6fw6q 3907 2 rate rate NN cord-006870-f5w6fw6q 3907 3 of of IN cord-006870-f5w6fw6q 3907 4 cerebrovascular cerebrovascular JJ cord-006870-f5w6fw6q 3907 5 complications complication NNS cord-006870-f5w6fw6q 3907 6 in in IN cord-006870-f5w6fw6q 3907 7 patients patient NNS cord-006870-f5w6fw6q 3907 8 treated treat VBN cord-006870-f5w6fw6q 3907 9 with with IN cord-006870-f5w6fw6q 3907 10 extracorporeal extracorporeal JJ cord-006870-f5w6fw6q 3907 11 membrane membrane NN cord-006870-f5w6fw6q 3907 12 oxygenation oxygenation NN cord-006870-f5w6fw6q 3907 13 ( ( -LRB- cord-006870-f5w6fw6q 3907 14 ECMO ECMO NNP cord-006870-f5w6fw6q 3907 15 ) ) -RRB- cord-006870-f5w6fw6q 3907 16 is be VBZ cord-006870-f5w6fw6q 3907 17 about about RB cord-006870-f5w6fw6q 3907 18 7 7 CD cord-006870-f5w6fw6q 3907 19 % % NN cord-006870-f5w6fw6q 3907 20 . . . cord-006870-f5w6fw6q 3908 1 Transcranial Transcranial NNP cord-006870-f5w6fw6q 3908 2 Doppler Doppler NNP cord-006870-f5w6fw6q 3908 3 ( ( -LRB- cord-006870-f5w6fw6q 3908 4 TCD TCD NNP cord-006870-f5w6fw6q 3908 5 ) ) -RRB- cord-006870-f5w6fw6q 3908 6 can can MD cord-006870-f5w6fw6q 3908 7 be be VB cord-006870-f5w6fw6q 3908 8 used use VBN cord-006870-f5w6fw6q 3908 9 to to TO cord-006870-f5w6fw6q 3908 10 noninvasively noninvasively RB cord-006870-f5w6fw6q 3908 11 monitor monitor VB cord-006870-f5w6fw6q 3908 12 cerebral cerebral JJ cord-006870-f5w6fw6q 3908 13 blood blood NN cord-006870-f5w6fw6q 3908 14 flow flow NN cord-006870-f5w6fw6q 3908 15 velocities velocity NNS cord-006870-f5w6fw6q 3908 16 ( ( -LRB- cord-006870-f5w6fw6q 3908 17 CBFVs cbfvs VBP cord-006870-f5w6fw6q 3908 18 ) ) -RRB- cord-006870-f5w6fw6q 3908 19 in in IN cord-006870-f5w6fw6q 3908 20 patients patient NNS cord-006870-f5w6fw6q 3908 21 undergoing undergo VBG cord-006870-f5w6fw6q 3908 22 ECMO ECMO NNP cord-006870-f5w6fw6q 3908 23 . . . cord-006870-f5w6fw6q 3909 1 The the DT cord-006870-f5w6fw6q 3909 2 aim aim NN cord-006870-f5w6fw6q 3909 3 of of IN cord-006870-f5w6fw6q 3909 4 this this DT cord-006870-f5w6fw6q 3909 5 study study NN cord-006870-f5w6fw6q 3909 6 is be VBZ cord-006870-f5w6fw6q 3909 7 to to TO cord-006870-f5w6fw6q 3909 8 describe describe VB cord-006870-f5w6fw6q 3909 9 TCD TCD NNP cord-006870-f5w6fw6q 3909 10 - - HYPH cord-006870-f5w6fw6q 3909 11 CBFV CBFV NNP cord-006870-f5w6fw6q 3909 12 patterns pattern NNS cord-006870-f5w6fw6q 3909 13 in in IN cord-006870-f5w6fw6q 3909 14 patients patient NNS cord-006870-f5w6fw6q 3909 15 undergoing undergo VBG cord-006870-f5w6fw6q 3909 16 venovenous venovenous JJ cord-006870-f5w6fw6q 3909 17 ( ( -LRB- cord-006870-f5w6fw6q 3909 18 VV VV NNP cord-006870-f5w6fw6q 3909 19 ) ) -RRB- cord-006870-f5w6fw6q 3909 20 and and CC cord-006870-f5w6fw6q 3909 21 venoarterial venoarterial NNP cord-006870-f5w6fw6q 3909 22 ( ( -LRB- cord-006870-f5w6fw6q 3909 23 VA VA NNP cord-006870-f5w6fw6q 3909 24 ) ) -RRB- cord-006870-f5w6fw6q 3909 25 ECMO ECMO NNP cord-006870-f5w6fw6q 3909 26 . . . cord-006870-f5w6fw6q 3910 1 A a DT cord-006870-f5w6fw6q 3910 2 neuro neuro JJ cord-006870-f5w6fw6q 3910 3 - - HYPH cord-006870-f5w6fw6q 3910 4 surveillance surveillance NN cord-006870-f5w6fw6q 3910 5 protocol protocol NN cord-006870-f5w6fw6q 3910 6 among among IN cord-006870-f5w6fw6q 3910 7 ECMO ECMO NNP cord-006870-f5w6fw6q 3910 8 patients patient NNS cord-006870-f5w6fw6q 3910 9 was be VBD cord-006870-f5w6fw6q 3910 10 initiated initiate VBN cord-006870-f5w6fw6q 3910 11 as as IN cord-006870-f5w6fw6q 3910 12 part part NN cord-006870-f5w6fw6q 3910 13 of of IN cord-006870-f5w6fw6q 3910 14 a a DT cord-006870-f5w6fw6q 3910 15 quality quality NN cord-006870-f5w6fw6q 3910 16 improvement improvement NN cord-006870-f5w6fw6q 3910 17 project project NN cord-006870-f5w6fw6q 3910 18 at at IN cord-006870-f5w6fw6q 3910 19 our -PRON- PRP$ cord-006870-f5w6fw6q 3910 20 institution institution NN cord-006870-f5w6fw6q 3910 21 . . . cord-006870-f5w6fw6q 3911 1 Daily daily JJ cord-006870-f5w6fw6q 3911 2 neurological neurological JJ cord-006870-f5w6fw6q 3911 3 exam exam NN cord-006870-f5w6fw6q 3911 4 , , , cord-006870-f5w6fw6q 3911 5 daily daily JJ cord-006870-f5w6fw6q 3911 6 TCD TCD NNP cord-006870-f5w6fw6q 3911 7 , , , cord-006870-f5w6fw6q 3911 8 brain brain NN cord-006870-f5w6fw6q 3911 9 - - HYPH cord-006870-f5w6fw6q 3911 10 CT CT NNP cord-006870-f5w6fw6q 3911 11 on on IN cord-006870-f5w6fw6q 3911 12 days day NNS cord-006870-f5w6fw6q 3911 13 one one CD cord-006870-f5w6fw6q 3911 14 and and CC cord-006870-f5w6fw6q 3911 15 three three CD cord-006870-f5w6fw6q 3911 16 and and CC cord-006870-f5w6fw6q 3911 17 24-hr 24-hr CD cord-006870-f5w6fw6q 3912 1 continuous continuous JJ cord-006870-f5w6fw6q 3912 2 EEG EEG NNP cord-006870-f5w6fw6q 3912 3 were be VBD cord-006870-f5w6fw6q 3912 4 performed perform VBN cord-006870-f5w6fw6q 3912 5 in in IN cord-006870-f5w6fw6q 3912 6 all all DT cord-006870-f5w6fw6q 3912 7 patients patient NNS cord-006870-f5w6fw6q 3912 8 undergoing undergo VBG cord-006870-f5w6fw6q 3912 9 VV VV NNP cord-006870-f5w6fw6q 3912 10 and and CC cord-006870-f5w6fw6q 3912 11 VA VA NNP cord-006870-f5w6fw6q 3912 12 - - HYPH cord-006870-f5w6fw6q 3912 13 ECMO ECMO NNP cord-006870-f5w6fw6q 3912 14 . . . cord-006870-f5w6fw6q 3913 1 Demographics demographic NNS cord-006870-f5w6fw6q 3913 2 , , , cord-006870-f5w6fw6q 3913 3 clinical clinical JJ cord-006870-f5w6fw6q 3913 4 and and CC cord-006870-f5w6fw6q 3913 5 imaging imaging NN cord-006870-f5w6fw6q 3913 6 data datum NNS cord-006870-f5w6fw6q 3913 7 were be VBD cord-006870-f5w6fw6q 3913 8 collected collect VBN cord-006870-f5w6fw6q 3913 9 for for IN cord-006870-f5w6fw6q 3913 10 the the DT cord-006870-f5w6fw6q 3913 11 duration duration NN cord-006870-f5w6fw6q 3913 12 of of IN cord-006870-f5w6fw6q 3913 13 ECMO ECMO NNP cord-006870-f5w6fw6q 3913 14 support support NN cord-006870-f5w6fw6q 3913 15 . . . cord-006870-f5w6fw6q 3914 1 CBFVs CBFVs NNP cord-006870-f5w6fw6q 3914 2 , , , cord-006870-f5w6fw6q 3914 3 lindegaard lindegaard NNP cord-006870-f5w6fw6q 3914 4 ratios ratio NNS cord-006870-f5w6fw6q 3914 5 ( ( -LRB- cord-006870-f5w6fw6q 3914 6 LR LR NNP cord-006870-f5w6fw6q 3914 7 ) ) -RRB- cord-006870-f5w6fw6q 3914 8 , , , cord-006870-f5w6fw6q 3914 9 pulsatility pulsatility NN cord-006870-f5w6fw6q 3914 10 index index NN cord-006870-f5w6fw6q 3914 11 ( ( -LRB- cord-006870-f5w6fw6q 3914 12 PI PI NNP cord-006870-f5w6fw6q 3914 13 ) ) -RRB- cord-006870-f5w6fw6q 3914 14 and and CC cord-006870-f5w6fw6q 3914 15 resistance resistance NN cord-006870-f5w6fw6q 3914 16 index index NN cord-006870-f5w6fw6q 3914 17 ( ( -LRB- cord-006870-f5w6fw6q 3914 18 RI RI NNP cord-006870-f5w6fw6q 3914 19 ) ) -RRB- cord-006870-f5w6fw6q 3914 20 on on IN cord-006870-f5w6fw6q 3914 21 TCD TCD NNP cord-006870-f5w6fw6q 3914 22 were be VBD cord-006870-f5w6fw6q 3914 23 collected collect VBN cord-006870-f5w6fw6q 3914 24 . . . cord-006870-f5w6fw6q 3915 1 Total total NN cord-006870-f5w6fw6q 3915 2 of of IN cord-006870-f5w6fw6q 3915 3 11 11 CD cord-006870-f5w6fw6q 3915 4 patients patient NNS cord-006870-f5w6fw6q 3915 5 were be VBD cord-006870-f5w6fw6q 3915 6 included include VBN cord-006870-f5w6fw6q 3915 7 in in IN cord-006870-f5w6fw6q 3915 8 the the DT cord-006870-f5w6fw6q 3915 9 study study NN cord-006870-f5w6fw6q 3915 10 [ [ -LRB- cord-006870-f5w6fw6q 3915 11 6 6 CD cord-006870-f5w6fw6q 3915 12 female female NN cord-006870-f5w6fw6q 3915 13 ( ( -LRB- cord-006870-f5w6fw6q 3915 14 55 55 CD cord-006870-f5w6fw6q 3915 15 % % NN cord-006870-f5w6fw6q 3915 16 ) ) -RRB- cord-006870-f5w6fw6q 3915 17 ; ; : cord-006870-f5w6fw6q 3915 18 9 9 CD cord-006870-f5w6fw6q 3915 19 Caucasians Caucasians NNPS cord-006870-f5w6fw6q 3915 20 ( ( -LRB- cord-006870-f5w6fw6q 3915 21 82 82 CD cord-006870-f5w6fw6q 3915 22 % % NN cord-006870-f5w6fw6q 3915 23 ) ) -RRB- cord-006870-f5w6fw6q 3915 24 ] ] -RRB- cord-006870-f5w6fw6q 3915 25 . . . cord-006870-f5w6fw6q 3916 1 Mean mean JJ cord-006870-f5w6fw6q 3916 2 age age NN cord-006870-f5w6fw6q 3916 3 was be VBD cord-006870-f5w6fw6q 3916 4 62 62 CD cord-006870-f5w6fw6q 3916 5 years year NNS cord-006870-f5w6fw6q 3916 6 . . . cord-006870-f5w6fw6q 3917 1 8 8 CD cord-006870-f5w6fw6q 3917 2 ( ( -LRB- cord-006870-f5w6fw6q 3917 3 73 73 CD cord-006870-f5w6fw6q 3917 4 % % NN cord-006870-f5w6fw6q 3917 5 ) ) -RRB- cord-006870-f5w6fw6q 3917 6 patients patient NNS cord-006870-f5w6fw6q 3917 7 received receive VBD cord-006870-f5w6fw6q 3917 8 VA VA NNP cord-006870-f5w6fw6q 3917 9 - - HYPH cord-006870-f5w6fw6q 3917 10 ECMO ECMO NNP cord-006870-f5w6fw6q 3917 11 ; ; : cord-006870-f5w6fw6q 3917 12 1 1 CD cord-006870-f5w6fw6q 3917 13 ( ( -LRB- cord-006870-f5w6fw6q 3917 14 9 9 CD cord-006870-f5w6fw6q 3917 15 % % NN cord-006870-f5w6fw6q 3917 16 ) ) -RRB- cord-006870-f5w6fw6q 3917 17 VV VV NNP cord-006870-f5w6fw6q 3917 18 - - HYPH cord-006870-f5w6fw6q 3917 19 ECMO ECMO NNP cord-006870-f5w6fw6q 3917 20 ; ; : cord-006870-f5w6fw6q 3917 21 2 2 CD cord-006870-f5w6fw6q 3917 22 ( ( -LRB- cord-006870-f5w6fw6q 3917 23 18.2 18.2 CD cord-006870-f5w6fw6q 3917 24 % % NN cord-006870-f5w6fw6q 3917 25 ) ) -RRB- cord-006870-f5w6fw6q 3917 26 received receive VBD cord-006870-f5w6fw6q 3917 27 both both CC cord-006870-f5w6fw6q 3917 28 VA VA NNP cord-006870-f5w6fw6q 3917 29 and and CC cord-006870-f5w6fw6q 3917 30 VV VV NNP cord-006870-f5w6fw6q 3917 31 - - HYPH cord-006870-f5w6fw6q 3917 32 ECMO ECMO NNP cord-006870-f5w6fw6q 3917 33 . . . cord-006870-f5w6fw6q 3918 1 Median median JJ cord-006870-f5w6fw6q 3918 2 days day NNS cord-006870-f5w6fw6q 3918 3 on on IN cord-006870-f5w6fw6q 3918 4 ECMO ECMO NNP cord-006870-f5w6fw6q 3918 5 was be VBD cord-006870-f5w6fw6q 3918 6 7 7 CD cord-006870-f5w6fw6q 3918 7 days day NNS cord-006870-f5w6fw6q 3918 8 . . . cord-006870-f5w6fw6q 3919 1 Median median JJ cord-006870-f5w6fw6q 3919 2 number number NN cord-006870-f5w6fw6q 3919 3 of of IN cord-006870-f5w6fw6q 3919 4 TCD TCD NNP cord-006870-f5w6fw6q 3919 5 studies study NNS cord-006870-f5w6fw6q 3919 6 performed perform VBN cord-006870-f5w6fw6q 3919 7 was be VBD cord-006870-f5w6fw6q 3919 8 2 2 CD cord-006870-f5w6fw6q 3919 9 ( ( -LRB- cord-006870-f5w6fw6q 3919 10 mean mean VB cord-006870-f5w6fw6q 3919 11 , , . cord-006870-f5w6fw6q 3920 1 3.45 3.45 CD cord-006870-f5w6fw6q 3920 2 _SP cord-006870-f5w6fw6q 3921 1 We -PRON- PRP cord-006870-f5w6fw6q 3921 2 observed observe VBD cord-006870-f5w6fw6q 3921 3 an an DT cord-006870-f5w6fw6q 3921 4 overall overall JJ cord-006870-f5w6fw6q 3921 5 pattern pattern NN cord-006870-f5w6fw6q 3921 6 of of IN cord-006870-f5w6fw6q 3921 7 low low JJ cord-006870-f5w6fw6q 3921 8 - - HYPH cord-006870-f5w6fw6q 3921 9 normal normal JJ cord-006870-f5w6fw6q 3921 10 flow flow NN cord-006870-f5w6fw6q 3921 11 CBFVs cbfv NNS cord-006870-f5w6fw6q 3921 12 and and CC cord-006870-f5w6fw6q 3921 13 reduced reduce VBN cord-006870-f5w6fw6q 3921 14 pulsatility pulsatility NN cord-006870-f5w6fw6q 3921 15 in in IN cord-006870-f5w6fw6q 3921 16 patients patient NNS cord-006870-f5w6fw6q 3921 17 on on IN cord-006870-f5w6fw6q 3921 18 VA VA NNP cord-006870-f5w6fw6q 3921 19 - - HYPH cord-006870-f5w6fw6q 3921 20 ECMO ECMO NNP cord-006870-f5w6fw6q 3921 21 . . . cord-006870-f5w6fw6q 3922 1 Nurse Nurse NNP cord-006870-f5w6fw6q 3922 2 Practitioner Practitioner NNP cord-006870-f5w6fw6q 3922 3 ( ( -LRB- cord-006870-f5w6fw6q 3922 4 NP NP NNP cord-006870-f5w6fw6q 3922 5 ) ) -RRB- cord-006870-f5w6fw6q 3922 6 and and CC cord-006870-f5w6fw6q 3922 7 Physician Physician NNP cord-006870-f5w6fw6q 3922 8 Assistant Assistant NNP cord-006870-f5w6fw6q 3922 9 ( ( -LRB- cord-006870-f5w6fw6q 3922 10 PA PA NNP cord-006870-f5w6fw6q 3922 11 ) ) -RRB- cord-006870-f5w6fw6q 3922 12 roles role NNS cord-006870-f5w6fw6q 3922 13 continue continue VBP cord-006870-f5w6fw6q 3922 14 to to TO cord-006870-f5w6fw6q 3922 15 expand expand VB cord-006870-f5w6fw6q 3922 16 in in IN cord-006870-f5w6fw6q 3922 17 the the DT cord-006870-f5w6fw6q 3922 18 critical critical JJ cord-006870-f5w6fw6q 3922 19 care care NN cord-006870-f5w6fw6q 3922 20 setting setting NN cord-006870-f5w6fw6q 3922 21 . . . cord-006870-f5w6fw6q 3923 1 Single single JJ cord-006870-f5w6fw6q 3923 2 and and CC cord-006870-f5w6fw6q 3923 3 multisite multisite JJ cord-006870-f5w6fw6q 3923 4 studies study NNS cord-006870-f5w6fw6q 3923 5 have have VBP cord-006870-f5w6fw6q 3923 6 examined examine VBN cord-006870-f5w6fw6q 3923 7 various various JJ cord-006870-f5w6fw6q 3923 8 aspects aspect NNS cord-006870-f5w6fw6q 3923 9 of of IN cord-006870-f5w6fw6q 3923 10 APP app NN cord-006870-f5w6fw6q 3923 11 practice practice NN cord-006870-f5w6fw6q 3923 12 , , , cord-006870-f5w6fw6q 3923 13 but but CC cord-006870-f5w6fw6q 3923 14 none none NN cord-006870-f5w6fw6q 3923 15 have have VBP cord-006870-f5w6fw6q 3923 16 focused focus VBN cord-006870-f5w6fw6q 3923 17 on on IN cord-006870-f5w6fw6q 3923 18 role role NN cord-006870-f5w6fw6q 3923 19 implementation implementation NN cord-006870-f5w6fw6q 3923 20 within within IN cord-006870-f5w6fw6q 3923 21 the the DT cord-006870-f5w6fw6q 3923 22 Neurologic Neurologic NNP cord-006870-f5w6fw6q 3923 23 Critical Critical NNP cord-006870-f5w6fw6q 3923 24 Care Care NNP cord-006870-f5w6fw6q 3923 25 Unit Unit NNP cord-006870-f5w6fw6q 3923 26 ( ( -LRB- cord-006870-f5w6fw6q 3923 27 NCCU NCCU NNP cord-006870-f5w6fw6q 3923 28 ) ) -RRB- cord-006870-f5w6fw6q 3923 29 . . . cord-006870-f5w6fw6q 3924 1 The the DT cord-006870-f5w6fw6q 3924 2 purpose purpose NN cord-006870-f5w6fw6q 3924 3 of of IN cord-006870-f5w6fw6q 3924 4 this this DT cord-006870-f5w6fw6q 3924 5 study study NN cord-006870-f5w6fw6q 3924 6 was be VBD cord-006870-f5w6fw6q 3924 7 to to TO cord-006870-f5w6fw6q 3924 8 obtain obtain VB cord-006870-f5w6fw6q 3924 9 foundational foundational JJ cord-006870-f5w6fw6q 3924 10 knowledge knowledge NN cord-006870-f5w6fw6q 3924 11 about about IN cord-006870-f5w6fw6q 3924 12 how how WRB cord-006870-f5w6fw6q 3924 13 NCCU NCCU NNP cord-006870-f5w6fw6q 3924 14 APPs app NNS cord-006870-f5w6fw6q 3924 15 are be VBP cord-006870-f5w6fw6q 3924 16 implementing implement VBG cord-006870-f5w6fw6q 3924 17 the the DT cord-006870-f5w6fw6q 3924 18 role role NN cord-006870-f5w6fw6q 3924 19 nationally nationally RB cord-006870-f5w6fw6q 3925 1 This this DT cord-006870-f5w6fw6q 3925 2 was be VBD cord-006870-f5w6fw6q 3925 3 a a DT cord-006870-f5w6fw6q 3925 4 voluntary voluntary JJ cord-006870-f5w6fw6q 3925 5 , , , cord-006870-f5w6fw6q 3925 6 cross cross JJ cord-006870-f5w6fw6q 3925 7 - - JJ cord-006870-f5w6fw6q 3925 8 sectional sectional JJ cord-006870-f5w6fw6q 3925 9 , , , cord-006870-f5w6fw6q 3925 10 descriptive descriptive JJ cord-006870-f5w6fw6q 3925 11 study study NN cord-006870-f5w6fw6q 3925 12 of of IN cord-006870-f5w6fw6q 3925 13 Nurse Nurse NNP cord-006870-f5w6fw6q 3925 14 Practitioners Practitioners NNP cord-006870-f5w6fw6q 3925 15 ( ( -LRB- cord-006870-f5w6fw6q 3925 16 NP NP NNP cord-006870-f5w6fw6q 3925 17 ) ) -RRB- cord-006870-f5w6fw6q 3925 18 and and CC cord-006870-f5w6fw6q 3925 19 Physician Physician NNP cord-006870-f5w6fw6q 3925 20 Assistant Assistant NNP cord-006870-f5w6fw6q 3925 21 ( ( -LRB- cord-006870-f5w6fw6q 3925 22 PA PA NNP cord-006870-f5w6fw6q 3925 23 ) ) -RRB- cord-006870-f5w6fw6q 3925 24 practicing practice VBG cord-006870-f5w6fw6q 3925 25 in in IN cord-006870-f5w6fw6q 3925 26 the the DT cord-006870-f5w6fw6q 3925 27 US US NNP cord-006870-f5w6fw6q 3925 28 . . . cord-006870-f5w6fw6q 3926 1 APPs app NNS cord-006870-f5w6fw6q 3926 2 were be VBD cord-006870-f5w6fw6q 3926 3 invited invite VBN cord-006870-f5w6fw6q 3926 4 to to TO cord-006870-f5w6fw6q 3926 5 participate participate VB cord-006870-f5w6fw6q 3926 6 in in IN cord-006870-f5w6fw6q 3926 7 this this DT cord-006870-f5w6fw6q 3926 8 voluntary voluntary JJ cord-006870-f5w6fw6q 3926 9 , , , cord-006870-f5w6fw6q 3926 10 70 70 CD cord-006870-f5w6fw6q 3926 11 item item NN cord-006870-f5w6fw6q 3926 12 survey survey NN cord-006870-f5w6fw6q 3926 13 . . . cord-006870-f5w6fw6q 3927 1 Distribution distribution NN cord-006870-f5w6fw6q 3927 2 occurred occur VBD cord-006870-f5w6fw6q 3927 3 initially initially RB cord-006870-f5w6fw6q 3927 4 through through IN cord-006870-f5w6fw6q 3927 5 email email NN cord-006870-f5w6fw6q 3927 6 inquiry inquiry NN cord-006870-f5w6fw6q 3927 7 via via IN cord-006870-f5w6fw6q 3927 8 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 3927 9 , , , cord-006870-f5w6fw6q 3927 10 professional professional JJ cord-006870-f5w6fw6q 3927 11 organization organization NN cord-006870-f5w6fw6q 3927 12 listservs listserv NNS cord-006870-f5w6fw6q 3928 1 ( ( -LRB- cord-006870-f5w6fw6q 3928 2 NCS NCS NNP cord-006870-f5w6fw6q 3928 3 , , , cord-006870-f5w6fw6q 3928 4 AACN AACN NNP cord-006870-f5w6fw6q 3928 5 , , , cord-006870-f5w6fw6q 3928 6 AANN AANN NNP cord-006870-f5w6fw6q 3928 7 ) ) -RRB- cord-006870-f5w6fw6q 3928 8 followed follow VBN cord-006870-f5w6fw6q 3928 9 by by IN cord-006870-f5w6fw6q 3928 10 snowball snowball NN cord-006870-f5w6fw6q 3928 11 effect effect NN cord-006870-f5w6fw6q 3928 12 circulation circulation NN cord-006870-f5w6fw6q 3928 13 . . . cord-006870-f5w6fw6q 3929 1 Enrollment enrollment NN cord-006870-f5w6fw6q 3929 2 occurred occur VBD cord-006870-f5w6fw6q 3929 3 from from IN cord-006870-f5w6fw6q 3929 4 March March NNP cord-006870-f5w6fw6q 3929 5 to to IN cord-006870-f5w6fw6q 3929 6 June June NNP cord-006870-f5w6fw6q 3929 7 2016 2016 CD cord-006870-f5w6fw6q 3929 8 . . . cord-006870-f5w6fw6q 3930 1 Data datum NNS cord-006870-f5w6fw6q 3930 2 was be VBD cord-006870-f5w6fw6q 3930 3 collected collect VBN cord-006870-f5w6fw6q 3930 4 in in IN cord-006870-f5w6fw6q 3930 5 RedCap RedCap NNP cord-006870-f5w6fw6q 3930 6 and and CC cord-006870-f5w6fw6q 3930 7 analyzed analyze VBD cord-006870-f5w6fw6q 3930 8 using use VBG cord-006870-f5w6fw6q 3930 9 SPSS SPSS NNP cord-006870-f5w6fw6q 3930 10 with with IN cord-006870-f5w6fw6q 3930 11 descriptive descriptive JJ cord-006870-f5w6fw6q 3930 12 statistics statistic NNS cord-006870-f5w6fw6q 3930 13 for for IN cord-006870-f5w6fw6q 3930 14 demographic demographic JJ cord-006870-f5w6fw6q 3930 15 , , , cord-006870-f5w6fw6q 3930 16 institutional institutional JJ cord-006870-f5w6fw6q 3930 17 , , , cord-006870-f5w6fw6q 3930 18 practice practice NN cord-006870-f5w6fw6q 3930 19 , , , cord-006870-f5w6fw6q 3930 20 role role NN cord-006870-f5w6fw6q 3930 21 characteristics characteristic NNS cord-006870-f5w6fw6q 3930 22 of of IN cord-006870-f5w6fw6q 3930 23 the the DT cord-006870-f5w6fw6q 3930 24 sample sample NN cord-006870-f5w6fw6q 3930 25 and and CC cord-006870-f5w6fw6q 3930 26 for for IN cord-006870-f5w6fw6q 3930 27 each each DT cord-006870-f5w6fw6q 3930 28 survey survey NN cord-006870-f5w6fw6q 3930 29 data data NN cord-006870-f5w6fw6q 3930 30 element element NN cord-006870-f5w6fw6q 3930 31 172 172 CD cord-006870-f5w6fw6q 3930 32 APP app NN cord-006870-f5w6fw6q 3930 33 participants participant NNS cord-006870-f5w6fw6q 3930 34 completed complete VBD cord-006870-f5w6fw6q 3930 35 the the DT cord-006870-f5w6fw6q 3930 36 survey survey NN cord-006870-f5w6fw6q 3930 37 : : : cord-006870-f5w6fw6q 3930 38 78 78 CD cord-006870-f5w6fw6q 3930 39 % % NN cord-006870-f5w6fw6q 3930 40 NP NP NNP cord-006870-f5w6fw6q 3930 41 , , , cord-006870-f5w6fw6q 3930 42 12 12 CD cord-006870-f5w6fw6q 3930 43 % % NN cord-006870-f5w6fw6q 3930 44 PA PA NNP cord-006870-f5w6fw6q 3930 45 , , , cord-006870-f5w6fw6q 3930 46 10 10 CD cord-006870-f5w6fw6q 3930 47 % % NN cord-006870-f5w6fw6q 3930 48 other other JJ cord-006870-f5w6fw6q 3930 49 . . . cord-006870-f5w6fw6q 3931 1 The the DT cord-006870-f5w6fw6q 3931 2 majority majority NN cord-006870-f5w6fw6q 3931 3 of of IN cord-006870-f5w6fw6q 3931 4 respondents respondent NNS cord-006870-f5w6fw6q 3931 5 were be VBD cord-006870-f5w6fw6q 3931 6 master master NNP cord-006870-f5w6fw6q 3931 7 's 's POS cord-006870-f5w6fw6q 3931 8 prepared prepare VBN cord-006870-f5w6fw6q 3931 9 ( ( -LRB- cord-006870-f5w6fw6q 3931 10 82.9 82.9 CD cord-006870-f5w6fw6q 3931 11 % % NN cord-006870-f5w6fw6q 3931 12 ) ) -RRB- cord-006870-f5w6fw6q 3932 1 acute acute JJ cord-006870-f5w6fw6q 3932 2 care care NN cord-006870-f5w6fw6q 3932 3 trained train VBN cord-006870-f5w6fw6q 3932 4 , , , cord-006870-f5w6fw6q 3932 5 ( ( -LRB- cord-006870-f5w6fw6q 3932 6 68.9 68.9 CD cord-006870-f5w6fw6q 3932 7 % % NN cord-006870-f5w6fw6q 3932 8 ) ) -RRB- cord-006870-f5w6fw6q 3932 9 and and CC cord-006870-f5w6fw6q 3932 10 hospital hospital NN cord-006870-f5w6fw6q 3932 11 employed employ VBN cord-006870-f5w6fw6q 3932 12 ( ( -LRB- cord-006870-f5w6fw6q 3932 13 81.4 81.4 CD cord-006870-f5w6fw6q 3932 14 % % NN cord-006870-f5w6fw6q 3932 15 ) ) -RRB- cord-006870-f5w6fw6q 3932 16 . . . cord-006870-f5w6fw6q 3933 1 Participants participant NNS cord-006870-f5w6fw6q 3933 2 were be VBD cord-006870-f5w6fw6q 3933 3 either either RB cord-006870-f5w6fw6q 3933 4 early early JJ cord-006870-f5w6fw6q 3933 5 in in IN cord-006870-f5w6fw6q 3933 6 their -PRON- PRP$ cord-006870-f5w6fw6q 3933 7 career career NN cord-006870-f5w6fw6q 3933 8 ( ( -LRB- cord-006870-f5w6fw6q 3933 9 38.7 38.7 CD cord-006870-f5w6fw6q 3933 10 % % NN cord-006870-f5w6fw6q 3933 11 1 1 CD cord-006870-f5w6fw6q 3933 12 - - SYM cord-006870-f5w6fw6q 3933 13 5 5 CD cord-006870-f5w6fw6q 3933 14 years year NNS cord-006870-f5w6fw6q 3933 15 as as IN cord-006870-f5w6fw6q 3933 16 APP app NN cord-006870-f5w6fw6q 3933 17 ) ) -RRB- cord-006870-f5w6fw6q 3933 18 or or CC cord-006870-f5w6fw6q 3933 19 experienced experience VBN cord-006870-f5w6fw6q 3933 20 ( ( -LRB- cord-006870-f5w6fw6q 3933 21 28.7 28.7 CD cord-006870-f5w6fw6q 3933 22 % % NN cord-006870-f5w6fw6q 3933 23 > > XX cord-006870-f5w6fw6q 3933 24 9 9 CD cord-006870-f5w6fw6q 3933 25 years year NNS cord-006870-f5w6fw6q 3933 26 ) ) -RRB- cord-006870-f5w6fw6q 3933 27 . . . cord-006870-f5w6fw6q 3934 1 81 81 CD cord-006870-f5w6fw6q 3934 2 % % NN cord-006870-f5w6fw6q 3934 3 work work NN cord-006870-f5w6fw6q 3934 4 in in IN cord-006870-f5w6fw6q 3934 5 a a DT cord-006870-f5w6fw6q 3934 6 direct direct JJ cord-006870-f5w6fw6q 3934 7 care care NN cord-006870-f5w6fw6q 3934 8 role role NN cord-006870-f5w6fw6q 3934 9 with with IN cord-006870-f5w6fw6q 3934 10 77 77 CD cord-006870-f5w6fw6q 3934 11 % % NN cord-006870-f5w6fw6q 3934 12 providing provide VBG cord-006870-f5w6fw6q 3934 13 total total JJ cord-006870-f5w6fw6q 3934 14 care care NN cord-006870-f5w6fw6q 3934 15 for for IN cord-006870-f5w6fw6q 3934 16 their -PRON- PRP$ cord-006870-f5w6fw6q 3934 17 patients patient NNS cord-006870-f5w6fw6q 3934 18 with with IN cord-006870-f5w6fw6q 3934 19 an an DT cord-006870-f5w6fw6q 3934 20 average average JJ cord-006870-f5w6fw6q 3934 21 daily daily JJ cord-006870-f5w6fw6q 3934 22 caseload caseload NN cord-006870-f5w6fw6q 3934 23 of of IN cord-006870-f5w6fw6q 3934 24 7.6 7.6 CD cord-006870-f5w6fw6q 3934 25 + + SYM cord-006870-f5w6fw6q 3934 26 3.4 3.4 CD cord-006870-f5w6fw6q 3934 27 patients patient NNS cord-006870-f5w6fw6q 3934 28 . . . cord-006870-f5w6fw6q 3935 1 63 63 CD cord-006870-f5w6fw6q 3935 2 % % NN cord-006870-f5w6fw6q 3935 3 of of IN cord-006870-f5w6fw6q 3935 4 providers provider NNS cord-006870-f5w6fw6q 3935 5 believed believe VBD cord-006870-f5w6fw6q 3935 6 3 3 CD cord-006870-f5w6fw6q 3935 7 - - SYM cord-006870-f5w6fw6q 3935 8 6 6 CD cord-006870-f5w6fw6q 3935 9 patients patient NNS cord-006870-f5w6fw6q 3935 10 was be VBD cord-006870-f5w6fw6q 3935 11 a a DT cord-006870-f5w6fw6q 3935 12 reasonable reasonable JJ cord-006870-f5w6fw6q 3935 13 caseload caseload NN cord-006870-f5w6fw6q 3935 14 for for IN cord-006870-f5w6fw6q 3935 15 total total JJ cord-006870-f5w6fw6q 3935 16 care care NN cord-006870-f5w6fw6q 3935 17 . . . cord-006870-f5w6fw6q 3936 1 In in IN cord-006870-f5w6fw6q 3936 2 addition addition NN cord-006870-f5w6fw6q 3936 3 to to IN cord-006870-f5w6fw6q 3936 4 the the DT cord-006870-f5w6fw6q 3936 5 NCCU NCCU NNP cord-006870-f5w6fw6q 3936 6 , , , cord-006870-f5w6fw6q 3936 7 28 28 CD cord-006870-f5w6fw6q 3936 8 % % NN cord-006870-f5w6fw6q 3936 9 of of IN cord-006870-f5w6fw6q 3936 10 participants participant NNS cord-006870-f5w6fw6q 3936 11 care care VBP cord-006870-f5w6fw6q 3936 12 for for IN cord-006870-f5w6fw6q 3936 13 patients patient NNS cord-006870-f5w6fw6q 3936 14 in in IN cord-006870-f5w6fw6q 3936 15 step step NN cord-006870-f5w6fw6q 3936 16 - - HYPH cord-006870-f5w6fw6q 3936 17 down down NN cord-006870-f5w6fw6q 3936 18 or or CC cord-006870-f5w6fw6q 3936 19 emergency emergency NN cord-006870-f5w6fw6q 3936 20 department department NN cord-006870-f5w6fw6q 3936 21 ( ( -LRB- cord-006870-f5w6fw6q 3936 22 36 36 CD cord-006870-f5w6fw6q 3936 23 % % NN cord-006870-f5w6fw6q 3936 24 ) ) -RRB- cord-006870-f5w6fw6q 3936 25 with with IN cord-006870-f5w6fw6q 3936 26 49 49 CD cord-006870-f5w6fw6q 3936 27 % % NN cord-006870-f5w6fw6q 3936 28 routinely routinely RB cord-006870-f5w6fw6q 3936 29 bilingl bilingl VBP cord-006870-f5w6fw6q 3936 30 for for IN cord-006870-f5w6fw6q 3936 31 their -PRON- PRP$ cord-006870-f5w6fw6q 3936 32 work work NN cord-006870-f5w6fw6q 3936 33 . . . cord-006870-f5w6fw6q 3937 1 This this DT cord-006870-f5w6fw6q 3937 2 study study NN cord-006870-f5w6fw6q 3937 3 is be VBZ cord-006870-f5w6fw6q 3937 4 the the DT cord-006870-f5w6fw6q 3937 5 first first JJ cord-006870-f5w6fw6q 3937 6 to to TO cord-006870-f5w6fw6q 3937 7 provide provide VB cord-006870-f5w6fw6q 3937 8 information information NN cord-006870-f5w6fw6q 3937 9 regarding regard VBG cord-006870-f5w6fw6q 3937 10 how how WRB cord-006870-f5w6fw6q 3937 11 NCC NCC NNP cord-006870-f5w6fw6q 3937 12 APPs app NNS cord-006870-f5w6fw6q 3937 13 are be VBP cord-006870-f5w6fw6q 3937 14 implementing implement VBG cord-006870-f5w6fw6q 3937 15 the the DT cord-006870-f5w6fw6q 3937 16 role role NN cord-006870-f5w6fw6q 3937 17 in in IN cord-006870-f5w6fw6q 3937 18 the the DT cord-006870-f5w6fw6q 3937 19 United United NNP cord-006870-f5w6fw6q 3937 20 States States NNP cord-006870-f5w6fw6q 3937 21 . . . cord-006870-f5w6fw6q 3938 1 This this DT cord-006870-f5w6fw6q 3938 2 study study NN cord-006870-f5w6fw6q 3938 3 provides provide VBZ cord-006870-f5w6fw6q 3938 4 benchmarking benchmarking NN cord-006870-f5w6fw6q 3938 5 data datum NNS cord-006870-f5w6fw6q 3938 6 which which WDT cord-006870-f5w6fw6q 3938 7 may may MD cord-006870-f5w6fw6q 3938 8 guide guide VB cord-006870-f5w6fw6q 3938 9 future future JJ cord-006870-f5w6fw6q 3938 10 research research NN cord-006870-f5w6fw6q 3938 11 with with IN cord-006870-f5w6fw6q 3938 12 this this DT cord-006870-f5w6fw6q 3938 13 population population NN cord-006870-f5w6fw6q 3938 14 as as RB cord-006870-f5w6fw6q 3938 15 well well RB cord-006870-f5w6fw6q 3938 16 as as IN cord-006870-f5w6fw6q 3938 17 serve serve VB cord-006870-f5w6fw6q 3938 18 as as IN cord-006870-f5w6fw6q 3938 19 a a DT cord-006870-f5w6fw6q 3938 20 template template NN cord-006870-f5w6fw6q 3938 21 for for IN cord-006870-f5w6fw6q 3938 22 evaluation evaluation NN cord-006870-f5w6fw6q 3938 23 of of IN cord-006870-f5w6fw6q 3938 24 other other JJ cord-006870-f5w6fw6q 3938 25 APP app NN cord-006870-f5w6fw6q 3938 26 specialty specialty NN cord-006870-f5w6fw6q 3938 27 roles role NNS cord-006870-f5w6fw6q 3938 28 . . . cord-006870-f5w6fw6q 3939 1 Despite despite IN cord-006870-f5w6fw6q 3939 2 advances advance NNS cord-006870-f5w6fw6q 3939 3 in in IN cord-006870-f5w6fw6q 3939 4 treatment treatment NN cord-006870-f5w6fw6q 3939 5 , , , cord-006870-f5w6fw6q 3939 6 the the DT cord-006870-f5w6fw6q 3939 7 median median JJ cord-006870-f5w6fw6q 3939 8 survival survival NN cord-006870-f5w6fw6q 3939 9 for for IN cord-006870-f5w6fw6q 3939 10 high high JJ cord-006870-f5w6fw6q 3939 11 grade grade NN cord-006870-f5w6fw6q 3939 12 gliomas glioma NNS cord-006870-f5w6fw6q 3939 13 ( ( -LRB- cord-006870-f5w6fw6q 3939 14 HGG HGG NNP cord-006870-f5w6fw6q 3939 15 ) ) -RRB- cord-006870-f5w6fw6q 3939 16 remains remain VBZ cord-006870-f5w6fw6q 3939 17 poor poor JJ cord-006870-f5w6fw6q 3939 18 . . . cord-006870-f5w6fw6q 3940 1 There there EX cord-006870-f5w6fw6q 3940 2 is be VBZ cord-006870-f5w6fw6q 3940 3 a a DT cord-006870-f5w6fw6q 3940 4 growing grow VBG cord-006870-f5w6fw6q 3940 5 body body NN cord-006870-f5w6fw6q 3940 6 of of IN cord-006870-f5w6fw6q 3940 7 research research NN cord-006870-f5w6fw6q 3940 8 showing show VBG cord-006870-f5w6fw6q 3940 9 that that IN cord-006870-f5w6fw6q 3940 10 palliative palliative JJ cord-006870-f5w6fw6q 3940 11 care care NN cord-006870-f5w6fw6q 3940 12 improves improve VBZ cord-006870-f5w6fw6q 3940 13 quality quality NN cord-006870-f5w6fw6q 3940 14 of of IN cord-006870-f5w6fw6q 3940 15 life life NN cord-006870-f5w6fw6q 3940 16 and and CC cord-006870-f5w6fw6q 3940 17 survival survival NN cord-006870-f5w6fw6q 3940 18 in in IN cord-006870-f5w6fw6q 3940 19 patients patient NNS cord-006870-f5w6fw6q 3940 20 with with IN cord-006870-f5w6fw6q 3940 21 advanced advanced JJ cord-006870-f5w6fw6q 3940 22 malignancies malignancy NNS cord-006870-f5w6fw6q 3940 23 . . . cord-006870-f5w6fw6q 3941 1 We -PRON- PRP cord-006870-f5w6fw6q 3941 2 sought seek VBD cord-006870-f5w6fw6q 3941 3 to to TO cord-006870-f5w6fw6q 3941 4 examine examine VB cord-006870-f5w6fw6q 3941 5 our -PRON- PRP$ cord-006870-f5w6fw6q 3941 6 own own JJ cord-006870-f5w6fw6q 3941 7 practices practice NNS cord-006870-f5w6fw6q 3941 8 in in IN cord-006870-f5w6fw6q 3941 9 the the DT cord-006870-f5w6fw6q 3941 10 Neurologic Neurologic NNP cord-006870-f5w6fw6q 3941 11 Intensive Intensive NNP cord-006870-f5w6fw6q 3941 12 Care Care NNP cord-006870-f5w6fw6q 3941 13 Unit Unit NNP cord-006870-f5w6fw6q 3941 14 ( ( -LRB- cord-006870-f5w6fw6q 3941 15 NICU NICU NNP cord-006870-f5w6fw6q 3941 16 ) ) -RRB- cord-006870-f5w6fw6q 3941 17 regarding regard VBG cord-006870-f5w6fw6q 3941 18 palliative palliative JJ cord-006870-f5w6fw6q 3941 19 care care NN cord-006870-f5w6fw6q 3941 20 consultation consultation NN cord-006870-f5w6fw6q 3941 21 in in IN cord-006870-f5w6fw6q 3941 22 this this DT cord-006870-f5w6fw6q 3941 23 population population NN cord-006870-f5w6fw6q 3941 24 . . . cord-006870-f5w6fw6q 3942 1 We -PRON- PRP cord-006870-f5w6fw6q 3942 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 3942 3 that that IN cord-006870-f5w6fw6q 3942 4 the the DT cord-006870-f5w6fw6q 3942 5 incidence incidence NN cord-006870-f5w6fw6q 3942 6 of of IN cord-006870-f5w6fw6q 3942 7 palliative palliative JJ cord-006870-f5w6fw6q 3942 8 care care NN cord-006870-f5w6fw6q 3942 9 consultation consultation NN cord-006870-f5w6fw6q 3942 10 is be VBZ cord-006870-f5w6fw6q 3942 11 low low JJ cord-006870-f5w6fw6q 3942 12 and and CC cord-006870-f5w6fw6q 3942 13 associated associate VBN cord-006870-f5w6fw6q 3942 14 with with IN cord-006870-f5w6fw6q 3942 15 a a DT cord-006870-f5w6fw6q 3942 16 clarification clarification NN cord-006870-f5w6fw6q 3942 17 of of IN cord-006870-f5w6fw6q 3942 18 patient patient NN cord-006870-f5w6fw6q 3942 19 's 's POS cord-006870-f5w6fw6q 3942 20 wishes wish NNS cord-006870-f5w6fw6q 3942 21 , , , cord-006870-f5w6fw6q 3942 22 measured measure VBN cord-006870-f5w6fw6q 3942 23 by by IN cord-006870-f5w6fw6q 3942 24 a a DT cord-006870-f5w6fw6q 3942 25 change change NN cord-006870-f5w6fw6q 3942 26 in in IN cord-006870-f5w6fw6q 3942 27 code code NN cord-006870-f5w6fw6q 3942 28 status status NN cord-006870-f5w6fw6q 3942 29 . . . cord-006870-f5w6fw6q 3943 1 We -PRON- PRP cord-006870-f5w6fw6q 3943 2 conducted conduct VBD cord-006870-f5w6fw6q 3943 3 a a DT cord-006870-f5w6fw6q 3943 4 retrospective retrospective JJ cord-006870-f5w6fw6q 3943 5 cohort cohort NN cord-006870-f5w6fw6q 3943 6 review review NN cord-006870-f5w6fw6q 3943 7 of of IN cord-006870-f5w6fw6q 3943 8 patients patient NNS cord-006870-f5w6fw6q 3943 9 with with IN cord-006870-f5w6fw6q 3943 10 previously previously RB cord-006870-f5w6fw6q 3943 11 diagnosed diagnose VBN cord-006870-f5w6fw6q 3943 12 HGG HGG NNP cord-006870-f5w6fw6q 3943 13 admitted admit VBD cord-006870-f5w6fw6q 3943 14 to to IN cord-006870-f5w6fw6q 3943 15 the the DT cord-006870-f5w6fw6q 3943 16 NICU NICU NNP cord-006870-f5w6fw6q 3943 17 from from IN cord-006870-f5w6fw6q 3943 18 2011 2011 CD cord-006870-f5w6fw6q 3943 19 - - SYM cord-006870-f5w6fw6q 3943 20 2016 2016 CD cord-006870-f5w6fw6q 3943 21 with with IN cord-006870-f5w6fw6q 3943 22 a a DT cord-006870-f5w6fw6q 3943 23 length length NN cord-006870-f5w6fw6q 3943 24 of of IN cord-006870-f5w6fw6q 3943 25 stay stay NN cord-006870-f5w6fw6q 3943 26 ( ( -LRB- cord-006870-f5w6fw6q 3943 27 LOS LOS NNP cord-006870-f5w6fw6q 3943 28 ) ) -RRB- cord-006870-f5w6fw6q 3943 29 greater great JJR cord-006870-f5w6fw6q 3943 30 than than IN cord-006870-f5w6fw6q 3943 31 48 48 CD cord-006870-f5w6fw6q 3943 32 hours hour NNS cord-006870-f5w6fw6q 3943 33 . . . cord-006870-f5w6fw6q 3944 1 The the DT cord-006870-f5w6fw6q 3944 2 primary primary JJ cord-006870-f5w6fw6q 3944 3 outcome outcome NN cord-006870-f5w6fw6q 3944 4 was be VBD cord-006870-f5w6fw6q 3944 5 the the DT cord-006870-f5w6fw6q 3944 6 incidence incidence NN cord-006870-f5w6fw6q 3944 7 of of IN cord-006870-f5w6fw6q 3944 8 patients patient NNS cord-006870-f5w6fw6q 3944 9 with with IN cord-006870-f5w6fw6q 3944 10 an an DT cord-006870-f5w6fw6q 3944 11 advanced advanced JJ cord-006870-f5w6fw6q 3944 12 directive directive NN cord-006870-f5w6fw6q 3944 13 or or CC cord-006870-f5w6fw6q 3944 14 inpatient inpatient JJ cord-006870-f5w6fw6q 3944 15 palliative palliative JJ cord-006870-f5w6fw6q 3944 16 care care NN cord-006870-f5w6fw6q 3944 17 consult consult NN cord-006870-f5w6fw6q 3944 18 ( ( -LRB- cord-006870-f5w6fw6q 3944 19 PCC PCC NNP cord-006870-f5w6fw6q 3944 20 ) ) -RRB- cord-006870-f5w6fw6q 3944 21 . . . cord-006870-f5w6fw6q 3945 1 Secondary secondary JJ cord-006870-f5w6fw6q 3945 2 outcomes outcome NNS cord-006870-f5w6fw6q 3945 3 included include VBD cord-006870-f5w6fw6q 3945 4 intensive intensive JJ cord-006870-f5w6fw6q 3945 5 care care NN cord-006870-f5w6fw6q 3945 6 unit unit NN cord-006870-f5w6fw6q 3945 7 LOS LOS NNP cord-006870-f5w6fw6q 3945 8 , , , cord-006870-f5w6fw6q 3945 9 change change NN cord-006870-f5w6fw6q 3945 10 in in IN cord-006870-f5w6fw6q 3945 11 code code NN cord-006870-f5w6fw6q 3945 12 status status NN cord-006870-f5w6fw6q 3945 13 and and CC cord-006870-f5w6fw6q 3945 14 location location NN cord-006870-f5w6fw6q 3945 15 of of IN cord-006870-f5w6fw6q 3945 16 death death NN cord-006870-f5w6fw6q 3945 17 . . . cord-006870-f5w6fw6q 3946 1 90 90 CD cord-006870-f5w6fw6q 3946 2 patients patient NNS cord-006870-f5w6fw6q 3946 3 were be VBD cord-006870-f5w6fw6q 3946 4 identified identify VBN cord-006870-f5w6fw6q 3946 5 with with IN cord-006870-f5w6fw6q 3946 6 HGG HGG NNP cord-006870-f5w6fw6q 3946 7 . . . cord-006870-f5w6fw6q 3947 1 The the DT cord-006870-f5w6fw6q 3947 2 mean mean JJ cord-006870-f5w6fw6q 3947 3 age age NN cord-006870-f5w6fw6q 3947 4 was be VBD cord-006870-f5w6fw6q 3947 5 59.5 59.5 CD cord-006870-f5w6fw6q 3947 6 years year NNS cord-006870-f5w6fw6q 3947 7 ( ( -LRB- cord-006870-f5w6fw6q 3947 8 19 19 CD cord-006870-f5w6fw6q 3947 9 - - SYM cord-006870-f5w6fw6q 3947 10 86years 86years CD cord-006870-f5w6fw6q 3947 11 ) ) -RRB- cord-006870-f5w6fw6q 3947 12 , , , cord-006870-f5w6fw6q 3947 13 64 64 CD cord-006870-f5w6fw6q 3947 14 % % NN cord-006870-f5w6fw6q 3947 15 were be VBD cord-006870-f5w6fw6q 3947 16 male male JJ cord-006870-f5w6fw6q 3947 17 , , , cord-006870-f5w6fw6q 3947 18 81 81 CD cord-006870-f5w6fw6q 3947 19 % % NN cord-006870-f5w6fw6q 3947 20 were be VBD cord-006870-f5w6fw6q 3947 21 white white JJ cord-006870-f5w6fw6q 3947 22 . . . cord-006870-f5w6fw6q 3948 1 Zero zero CD cord-006870-f5w6fw6q 3948 2 patients patient NNS cord-006870-f5w6fw6q 3948 3 were be VBD cord-006870-f5w6fw6q 3948 4 admitted admit VBN cord-006870-f5w6fw6q 3948 5 with with IN cord-006870-f5w6fw6q 3948 6 an an DT cord-006870-f5w6fw6q 3948 7 advanced advanced JJ cord-006870-f5w6fw6q 3948 8 directive directive NN cord-006870-f5w6fw6q 3948 9 on on IN cord-006870-f5w6fw6q 3948 10 admission admission NN cord-006870-f5w6fw6q 3948 11 . . . cord-006870-f5w6fw6q 3949 1 PCC PCC NNP cord-006870-f5w6fw6q 3949 2 was be VBD cord-006870-f5w6fw6q 3949 3 obtained obtain VBN cord-006870-f5w6fw6q 3949 4 in in IN cord-006870-f5w6fw6q 3949 5 16 16 CD cord-006870-f5w6fw6q 3949 6 patients patient NNS cord-006870-f5w6fw6q 3949 7 ( ( -LRB- cord-006870-f5w6fw6q 3949 8 18 18 CD cord-006870-f5w6fw6q 3949 9 % % NN cord-006870-f5w6fw6q 3949 10 ) ) -RRB- cord-006870-f5w6fw6q 3949 11 . . . cord-006870-f5w6fw6q 3950 1 PCC PCC NNP cord-006870-f5w6fw6q 3950 2 was be VBD cord-006870-f5w6fw6q 3950 3 associated associate VBN cord-006870-f5w6fw6q 3950 4 with with IN cord-006870-f5w6fw6q 3950 5 increased increase VBN cord-006870-f5w6fw6q 3950 6 NICU NICU NNP cord-006870-f5w6fw6q 3950 7 stay stay NN cord-006870-f5w6fw6q 3950 8 ( ( -LRB- cord-006870-f5w6fw6q 3950 9 254 254 CD cord-006870-f5w6fw6q 3950 10 hrs hrs NN cord-006870-f5w6fw6q 3950 11 vs vs IN cord-006870-f5w6fw6q 3950 12 63 63 CD cord-006870-f5w6fw6q 3950 13 hrs hrs NN cord-006870-f5w6fw6q 3950 14 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 3950 15 ) ) -RRB- cord-006870-f5w6fw6q 3950 16 , , , cord-006870-f5w6fw6q 3950 17 a a DT cord-006870-f5w6fw6q 3950 18 change change NN cord-006870-f5w6fw6q 3950 19 in in IN cord-006870-f5w6fw6q 3950 20 code code NN cord-006870-f5w6fw6q 3950 21 status status NN cord-006870-f5w6fw6q 3950 22 to to TO cord-006870-f5w6fw6q 3950 23 do do VB cord-006870-f5w6fw6q 3950 24 not not RB cord-006870-f5w6fw6q 3950 25 resuscitate resuscitate VB cord-006870-f5w6fw6q 3950 26 ( ( -LRB- cord-006870-f5w6fw6q 3950 27 69 69 CD cord-006870-f5w6fw6q 3950 28 % % NN cord-006870-f5w6fw6q 3950 29 vs vs IN cord-006870-f5w6fw6q 3950 30 11 11 CD cord-006870-f5w6fw6q 3950 31 % % NN cord-006870-f5w6fw6q 3950 32 p=0.00001 p=0.00001 NNS cord-006870-f5w6fw6q 3950 33 ) ) -RRB- cord-006870-f5w6fw6q 3950 34 , , , cord-006870-f5w6fw6q 3950 35 and and CC cord-006870-f5w6fw6q 3950 36 an an DT cord-006870-f5w6fw6q 3950 37 increased increase VBN cord-006870-f5w6fw6q 3950 38 likelihood likelihood NN cord-006870-f5w6fw6q 3950 39 to to TO cord-006870-f5w6fw6q 3950 40 not not RB cord-006870-f5w6fw6q 3950 41 die die VB cord-006870-f5w6fw6q 3950 42 in in IN cord-006870-f5w6fw6q 3950 43 the the DT cord-006870-f5w6fw6q 3950 44 hospital hospital NN cord-006870-f5w6fw6q 3950 45 ( ( -LRB- cord-006870-f5w6fw6q 3950 46 92 92 CD cord-006870-f5w6fw6q 3950 47 % % NN cord-006870-f5w6fw6q 3950 48 vs vs IN cord-006870-f5w6fw6q 3950 49 58 58 CD cord-006870-f5w6fw6q 3950 50 % % NN cord-006870-f5w6fw6q 3950 51 p=0.08 p=0.08 NN cord-006870-f5w6fw6q 3950 52 ) ) -RRB- cord-006870-f5w6fw6q 3950 53 . . . cord-006870-f5w6fw6q 3951 1 At at IN cord-006870-f5w6fw6q 3951 2 our -PRON- PRP$ cord-006870-f5w6fw6q 3951 3 large large JJ cord-006870-f5w6fw6q 3951 4 academic academic JJ cord-006870-f5w6fw6q 3951 5 tertiary tertiary JJ cord-006870-f5w6fw6q 3951 6 care care NN cord-006870-f5w6fw6q 3951 7 facility facility NN cord-006870-f5w6fw6q 3951 8 intensivists intensivist NNS cord-006870-f5w6fw6q 3951 9 underutilize underutilize VBP cord-006870-f5w6fw6q 3951 10 palliative palliative JJ cord-006870-f5w6fw6q 3951 11 care care NN cord-006870-f5w6fw6q 3951 12 services service NNS cord-006870-f5w6fw6q 3951 13 for for IN cord-006870-f5w6fw6q 3951 14 HGG HGG NNP cord-006870-f5w6fw6q 3951 15 patients patient NNS cord-006870-f5w6fw6q 3951 16 . . . cord-006870-f5w6fw6q 3952 1 Patients patient NNS cord-006870-f5w6fw6q 3952 2 with with IN cord-006870-f5w6fw6q 3952 3 fatal fatal JJ cord-006870-f5w6fw6q 3952 4 brain brain NN cord-006870-f5w6fw6q 3952 5 tumors tumor NNS cord-006870-f5w6fw6q 3952 6 are be VBP cord-006870-f5w6fw6q 3952 7 not not RB cord-006870-f5w6fw6q 3952 8 having have VBG cord-006870-f5w6fw6q 3952 9 end end NN cord-006870-f5w6fw6q 3952 10 of of IN cord-006870-f5w6fw6q 3952 11 life life NN cord-006870-f5w6fw6q 3952 12 discussions discussion NNS cord-006870-f5w6fw6q 3952 13 prior prior RB cord-006870-f5w6fw6q 3952 14 to to IN cord-006870-f5w6fw6q 3952 15 admission admission NN cord-006870-f5w6fw6q 3952 16 , , , cord-006870-f5w6fw6q 3952 17 indicating indicate VBG cord-006870-f5w6fw6q 3952 18 a a DT cord-006870-f5w6fw6q 3952 19 need need NN cord-006870-f5w6fw6q 3952 20 for for IN cord-006870-f5w6fw6q 3952 21 early early JJ cord-006870-f5w6fw6q 3952 22 palliative palliative JJ cord-006870-f5w6fw6q 3952 23 care care NN cord-006870-f5w6fw6q 3952 24 intervention intervention NN cord-006870-f5w6fw6q 3952 25 . . . cord-006870-f5w6fw6q 3953 1 Patients patient NNS cord-006870-f5w6fw6q 3953 2 are be VBP cord-006870-f5w6fw6q 3953 3 six six CD cord-006870-f5w6fw6q 3953 4 times time NNS cord-006870-f5w6fw6q 3953 5 more more RBR cord-006870-f5w6fw6q 3953 6 likely likely JJ cord-006870-f5w6fw6q 3953 7 to to TO cord-006870-f5w6fw6q 3953 8 change change VB cord-006870-f5w6fw6q 3953 9 their -PRON- PRP$ cord-006870-f5w6fw6q 3953 10 code code NN cord-006870-f5w6fw6q 3953 11 status status NN cord-006870-f5w6fw6q 3953 12 and and CC cord-006870-f5w6fw6q 3953 13 there there EX cord-006870-f5w6fw6q 3953 14 is be VBZ cord-006870-f5w6fw6q 3953 15 a a DT cord-006870-f5w6fw6q 3953 16 trend trend NN cord-006870-f5w6fw6q 3953 17 towards towards IN cord-006870-f5w6fw6q 3953 18 dying die VBG cord-006870-f5w6fw6q 3953 19 outside outside RB cord-006870-f5w6fw6q 3953 20 of of IN cord-006870-f5w6fw6q 3953 21 the the DT cord-006870-f5w6fw6q 3953 22 hospital hospital NN cord-006870-f5w6fw6q 3953 23 if if IN cord-006870-f5w6fw6q 3953 24 they -PRON- PRP cord-006870-f5w6fw6q 3953 25 receive receive VBP cord-006870-f5w6fw6q 3953 26 a a DT cord-006870-f5w6fw6q 3953 27 palliative palliative JJ cord-006870-f5w6fw6q 3953 28 care care NN cord-006870-f5w6fw6q 3953 29 consult consult NN cord-006870-f5w6fw6q 3953 30 . . . cord-006870-f5w6fw6q 3954 1 Hypertonic Hypertonic NNP cord-006870-f5w6fw6q 3954 2 saline saline NN cord-006870-f5w6fw6q 3954 3 ( ( -LRB- cord-006870-f5w6fw6q 3954 4 HTS HTS NNP cord-006870-f5w6fw6q 3954 5 ) ) -RRB- cord-006870-f5w6fw6q 3954 6 , , , cord-006870-f5w6fw6q 3954 7 a a DT cord-006870-f5w6fw6q 3954 8 hyperosmolar hyperosmolar JJ cord-006870-f5w6fw6q 3954 9 solution solution NN cord-006870-f5w6fw6q 3954 10 , , , cord-006870-f5w6fw6q 3954 11 is be VBZ cord-006870-f5w6fw6q 3954 12 typically typically RB cord-006870-f5w6fw6q 3954 13 administered administer VBN cord-006870-f5w6fw6q 3954 14 using use VBG cord-006870-f5w6fw6q 3954 15 a a DT cord-006870-f5w6fw6q 3954 16 central central JJ cord-006870-f5w6fw6q 3954 17 venous venous JJ cord-006870-f5w6fw6q 3954 18 catheter catheter NN cord-006870-f5w6fw6q 3954 19 ( ( -LRB- cord-006870-f5w6fw6q 3954 20 CVC CVC NNP cord-006870-f5w6fw6q 3954 21 ) ) -RRB- cord-006870-f5w6fw6q 3954 22 due due IN cord-006870-f5w6fw6q 3954 23 to to IN cord-006870-f5w6fw6q 3954 24 concerns concern NNS cord-006870-f5w6fw6q 3954 25 of of IN cord-006870-f5w6fw6q 3954 26 extravasation extravasation NN cord-006870-f5w6fw6q 3954 27 , , , cord-006870-f5w6fw6q 3954 28 but but CC cord-006870-f5w6fw6q 3954 29 a a DT cord-006870-f5w6fw6q 3954 30 CVC CVC NNP cord-006870-f5w6fw6q 3954 31 is be VBZ cord-006870-f5w6fw6q 3954 32 rarely rarely RB cord-006870-f5w6fw6q 3954 33 readily readily RB cord-006870-f5w6fw6q 3954 34 available available JJ cord-006870-f5w6fw6q 3954 35 . . . cord-006870-f5w6fw6q 3955 1 In in IN cord-006870-f5w6fw6q 3955 2 emergent emergent JJ cord-006870-f5w6fw6q 3955 3 situations situation NNS cord-006870-f5w6fw6q 3955 4 , , , cord-006870-f5w6fw6q 3955 5 intraosseous intraosseous JJ cord-006870-f5w6fw6q 3955 6 ( ( -LRB- cord-006870-f5w6fw6q 3955 7 IO IO NNP cord-006870-f5w6fw6q 3955 8 ) ) -RRB- cord-006870-f5w6fw6q 3955 9 access access NN cord-006870-f5w6fw6q 3955 10 is be VBZ cord-006870-f5w6fw6q 3955 11 used use VBN cord-006870-f5w6fw6q 3955 12 when when WRB cord-006870-f5w6fw6q 3955 13 peripheral peripheral JJ cord-006870-f5w6fw6q 3955 14 intravenous intravenous JJ cord-006870-f5w6fw6q 3955 15 access access NN cord-006870-f5w6fw6q 3955 16 is be VBZ cord-006870-f5w6fw6q 3955 17 not not RB cord-006870-f5w6fw6q 3955 18 available available JJ cord-006870-f5w6fw6q 3955 19 . . . cord-006870-f5w6fw6q 3956 1 Existing exist VBG cord-006870-f5w6fw6q 3956 2 literature literature NN cord-006870-f5w6fw6q 3956 3 does do VBZ cord-006870-f5w6fw6q 3956 4 not not RB cord-006870-f5w6fw6q 3956 5 address address VB cord-006870-f5w6fw6q 3956 6 the the DT cord-006870-f5w6fw6q 3956 7 administration administration NN cord-006870-f5w6fw6q 3956 8 of of IN cord-006870-f5w6fw6q 3956 9 hypertonic hypertonic NNP cord-006870-f5w6fw6q 3956 10 saline saline NNP cord-006870-f5w6fw6q 3956 11 using use VBG cord-006870-f5w6fw6q 3956 12 IO IO NNP cord-006870-f5w6fw6q 3956 13 access access NN cord-006870-f5w6fw6q 3956 14 for for IN cord-006870-f5w6fw6q 3956 15 adult adult NN cord-006870-f5w6fw6q 3956 16 patients patient NNS cord-006870-f5w6fw6q 3956 17 with with IN cord-006870-f5w6fw6q 3956 18 brain brain NN cord-006870-f5w6fw6q 3956 19 injury injury NN cord-006870-f5w6fw6q 3956 20 . . . cord-006870-f5w6fw6q 3957 1 The the DT cord-006870-f5w6fw6q 3957 2 administration administration NN cord-006870-f5w6fw6q 3957 3 of of IN cord-006870-f5w6fw6q 3957 4 HTS HTS NNP cord-006870-f5w6fw6q 3957 5 is be VBZ cord-006870-f5w6fw6q 3957 6 often often RB cord-006870-f5w6fw6q 3957 7 delayed delay VBN cord-006870-f5w6fw6q 3957 8 due due IN cord-006870-f5w6fw6q 3957 9 to to IN cord-006870-f5w6fw6q 3957 10 the the DT cord-006870-f5w6fw6q 3957 11 time time NN cord-006870-f5w6fw6q 3957 12 taken take VBN cord-006870-f5w6fw6q 3957 13 to to TO cord-006870-f5w6fw6q 3957 14 obtain obtain VB cord-006870-f5w6fw6q 3957 15 a a DT cord-006870-f5w6fw6q 3957 16 central central JJ cord-006870-f5w6fw6q 3957 17 venous venous JJ cord-006870-f5w6fw6q 3957 18 access access NN cord-006870-f5w6fw6q 3957 19 . . . cord-006870-f5w6fw6q 3958 1 Insertion insertion NN cord-006870-f5w6fw6q 3958 2 of of IN cord-006870-f5w6fw6q 3958 3 an an DT cord-006870-f5w6fw6q 3958 4 IO IO NNP cord-006870-f5w6fw6q 3958 5 needle needle NN cord-006870-f5w6fw6q 3958 6 is be VBZ cord-006870-f5w6fw6q 3958 7 typically typically RB cord-006870-f5w6fw6q 3958 8 much much RB cord-006870-f5w6fw6q 3958 9 faster fast JJR cord-006870-f5w6fw6q 3958 10 than than IN cord-006870-f5w6fw6q 3958 11 a a DT cord-006870-f5w6fw6q 3958 12 CVC CVC NNP cord-006870-f5w6fw6q 3958 13 . . . cord-006870-f5w6fw6q 3959 1 We -PRON- PRP cord-006870-f5w6fw6q 3959 2 report report VBP cord-006870-f5w6fw6q 3959 3 the the DT cord-006870-f5w6fw6q 3959 4 safety safety NN cord-006870-f5w6fw6q 3959 5 and and CC cord-006870-f5w6fw6q 3959 6 tolerability tolerability NN cord-006870-f5w6fw6q 3959 7 of of IN cord-006870-f5w6fw6q 3959 8 HTS HTS NNP cord-006870-f5w6fw6q 3959 9 using use VBG cord-006870-f5w6fw6q 3959 10 IO IO NNP cord-006870-f5w6fw6q 3959 11 route route NN cord-006870-f5w6fw6q 3959 12 . . . cord-006870-f5w6fw6q 3960 1 A a DT cord-006870-f5w6fw6q 3960 2 prospective prospective JJ cord-006870-f5w6fw6q 3960 3 pilot pilot NN cord-006870-f5w6fw6q 3960 4 study study NN cord-006870-f5w6fw6q 3960 5 on on IN cord-006870-f5w6fw6q 3960 6 the the DT cord-006870-f5w6fw6q 3960 7 safety safety NN cord-006870-f5w6fw6q 3960 8 and and CC cord-006870-f5w6fw6q 3960 9 tolerability tolerability NN cord-006870-f5w6fw6q 3960 10 of of IN cord-006870-f5w6fw6q 3960 11 3 3 CD cord-006870-f5w6fw6q 3960 12 % % NN cord-006870-f5w6fw6q 3960 13 HTS HTS NNP cord-006870-f5w6fw6q 3960 14 via via IN cord-006870-f5w6fw6q 3960 15 IO IO NNP cord-006870-f5w6fw6q 3960 16 is be VBZ cord-006870-f5w6fw6q 3960 17 currently currently RB cord-006870-f5w6fw6q 3960 18 underway underway JJ cord-006870-f5w6fw6q 3960 19 . . . cord-006870-f5w6fw6q 3961 1 Data datum NNS cord-006870-f5w6fw6q 3961 2 on on IN cord-006870-f5w6fw6q 3961 3 local local JJ cord-006870-f5w6fw6q 3961 4 complications complication NNS cord-006870-f5w6fw6q 3961 5 at at IN cord-006870-f5w6fw6q 3961 6 the the DT cord-006870-f5w6fw6q 3961 7 site site NN cord-006870-f5w6fw6q 3961 8 of of IN cord-006870-f5w6fw6q 3961 9 injection injection NN cord-006870-f5w6fw6q 3961 10 , , , cord-006870-f5w6fw6q 3961 11 pain pain NN cord-006870-f5w6fw6q 3961 12 during during IN cord-006870-f5w6fw6q 3961 13 insertion insertion NN cord-006870-f5w6fw6q 3961 14 and and CC cord-006870-f5w6fw6q 3961 15 during during IN cord-006870-f5w6fw6q 3961 16 infusion infusion NN cord-006870-f5w6fw6q 3961 17 , , , cord-006870-f5w6fw6q 3961 18 and and CC cord-006870-f5w6fw6q 3961 19 serial serial JJ cord-006870-f5w6fw6q 3961 20 serum serum NN cord-006870-f5w6fw6q 3961 21 sodium sodium NN cord-006870-f5w6fw6q 3961 22 levels level NNS cord-006870-f5w6fw6q 3961 23 were be VBD cord-006870-f5w6fw6q 3961 24 collected collect VBN cord-006870-f5w6fw6q 3961 25 . . . cord-006870-f5w6fw6q 3962 1 Additionally additionally RB cord-006870-f5w6fw6q 3962 2 , , , cord-006870-f5w6fw6q 3962 3 we -PRON- PRP cord-006870-f5w6fw6q 3962 4 report report VBP cord-006870-f5w6fw6q 3962 5 a a DT cord-006870-f5w6fw6q 3962 6 case case NN cord-006870-f5w6fw6q 3962 7 of of IN cord-006870-f5w6fw6q 3962 8 successful successful JJ cord-006870-f5w6fw6q 3962 9 administration administration NN cord-006870-f5w6fw6q 3962 10 of of IN cord-006870-f5w6fw6q 3962 11 23.4 23.4 CD cord-006870-f5w6fw6q 3962 12 % % NN cord-006870-f5w6fw6q 3962 13 HTS HTS NNP cord-006870-f5w6fw6q 3962 14 using use VBG cord-006870-f5w6fw6q 3962 15 the the DT cord-006870-f5w6fw6q 3962 16 IO IO NNP cord-006870-f5w6fw6q 3962 17 route route NN cord-006870-f5w6fw6q 3962 18 . . . cord-006870-f5w6fw6q 3963 1 Preliminary preliminary JJ cord-006870-f5w6fw6q 3963 2 data datum NNS cord-006870-f5w6fw6q 3963 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 3963 4 that that IN cord-006870-f5w6fw6q 3963 5 3 3 CD cord-006870-f5w6fw6q 3963 6 % % NN cord-006870-f5w6fw6q 3963 7 HTS HTS NNP cord-006870-f5w6fw6q 3963 8 was be VBD cord-006870-f5w6fw6q 3963 9 well well RB cord-006870-f5w6fw6q 3963 10 - - HYPH cord-006870-f5w6fw6q 3963 11 tolerated tolerate VBN cord-006870-f5w6fw6q 3963 12 , , , cord-006870-f5w6fw6q 3963 13 with with IN cord-006870-f5w6fw6q 3963 14 no no DT cord-006870-f5w6fw6q 3963 15 reports report NNS cord-006870-f5w6fw6q 3963 16 of of IN cord-006870-f5w6fw6q 3963 17 severe severe JJ cord-006870-f5w6fw6q 3963 18 pain pain NN cord-006870-f5w6fw6q 3963 19 , , , cord-006870-f5w6fw6q 3963 20 infections infection NNS cord-006870-f5w6fw6q 3963 21 , , , cord-006870-f5w6fw6q 3963 22 extravasation extravasation NN cord-006870-f5w6fw6q 3963 23 , , , cord-006870-f5w6fw6q 3963 24 soft soft JJ cord-006870-f5w6fw6q 3963 25 tissue tissue NN cord-006870-f5w6fw6q 3963 26 injury injury NN cord-006870-f5w6fw6q 3963 27 or or CC cord-006870-f5w6fw6q 3963 28 local local JJ cord-006870-f5w6fw6q 3963 29 infectious infectious JJ cord-006870-f5w6fw6q 3963 30 complications complication NNS cord-006870-f5w6fw6q 3963 31 in in IN cord-006870-f5w6fw6q 3963 32 our -PRON- PRP$ cord-006870-f5w6fw6q 3963 33 sample sample NN cord-006870-f5w6fw6q 3963 34 of of IN cord-006870-f5w6fw6q 3963 35 patients patient NNS cord-006870-f5w6fw6q 3963 36 with with IN cord-006870-f5w6fw6q 3963 37 brain brain NN cord-006870-f5w6fw6q 3963 38 injury injury NN cord-006870-f5w6fw6q 3963 39 . . . cord-006870-f5w6fw6q 3964 1 Indications indication NNS cord-006870-f5w6fw6q 3964 2 for for IN cord-006870-f5w6fw6q 3964 3 use use NN cord-006870-f5w6fw6q 3964 4 of of IN cord-006870-f5w6fw6q 3964 5 hypertonic hypertonic JJ cord-006870-f5w6fw6q 3964 6 saline saline NN cord-006870-f5w6fw6q 3964 7 included include VBD cord-006870-f5w6fw6q 3964 8 patients patient NNS cord-006870-f5w6fw6q 3964 9 with with IN cord-006870-f5w6fw6q 3964 10 cerebral cerebral JJ cord-006870-f5w6fw6q 3964 11 edema edema NN cord-006870-f5w6fw6q 3964 12 and and CC cord-006870-f5w6fw6q 3964 13 mass mass JJ cord-006870-f5w6fw6q 3964 14 effect effect NN cord-006870-f5w6fw6q 3964 15 from from IN cord-006870-f5w6fw6q 3964 16 intracerebral intracerebral JJ cord-006870-f5w6fw6q 3964 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 3964 18 . . . cord-006870-f5w6fw6q 3965 1 An an DT cord-006870-f5w6fw6q 3965 2 appropriate appropriate JJ cord-006870-f5w6fw6q 3965 3 rise rise NN cord-006870-f5w6fw6q 3965 4 of of IN cord-006870-f5w6fw6q 3965 5 serum serum NN cord-006870-f5w6fw6q 3965 6 sodium sodium NN cord-006870-f5w6fw6q 3965 7 levels level NNS cord-006870-f5w6fw6q 3965 8 by by IN cord-006870-f5w6fw6q 3965 9 approximately approximately RB cord-006870-f5w6fw6q 3965 10 1 1 CD cord-006870-f5w6fw6q 3965 11 mmol mmol NNP cord-006870-f5w6fw6q 3965 12 / / SYM cord-006870-f5w6fw6q 3965 13 L L NNP cord-006870-f5w6fw6q 3965 14 / / SYM cord-006870-f5w6fw6q 3965 15 hr hr NN cord-006870-f5w6fw6q 3965 16 in in IN cord-006870-f5w6fw6q 3965 17 was be VBD cord-006870-f5w6fw6q 3965 18 observed observe VBN cord-006870-f5w6fw6q 3965 19 . . . cord-006870-f5w6fw6q 3966 1 In in IN cord-006870-f5w6fw6q 3966 2 the the DT cord-006870-f5w6fw6q 3966 3 case case NN cord-006870-f5w6fw6q 3966 4 where where WRB cord-006870-f5w6fw6q 3966 5 30 30 CD cord-006870-f5w6fw6q 3966 6 ml ml NNS cord-006870-f5w6fw6q 3966 7 of of IN cord-006870-f5w6fw6q 3966 8 23.4 23.4 CD cord-006870-f5w6fw6q 3966 9 % % NN cord-006870-f5w6fw6q 3966 10 HTS HTS NNP cord-006870-f5w6fw6q 3966 11 , , , cord-006870-f5w6fw6q 3966 12 no no DT cord-006870-f5w6fw6q 3966 13 local local JJ cord-006870-f5w6fw6q 3966 14 complications complication NNS cord-006870-f5w6fw6q 3966 15 were be VBD cord-006870-f5w6fw6q 3966 16 observed observe VBN cord-006870-f5w6fw6q 3966 17 and and CC cord-006870-f5w6fw6q 3966 18 serum serum NN cord-006870-f5w6fw6q 3966 19 sodium sodium NN cord-006870-f5w6fw6q 3966 20 levels level NNS cord-006870-f5w6fw6q 3966 21 rose rise VBD cord-006870-f5w6fw6q 3966 22 appropriately appropriately RB cord-006870-f5w6fw6q 3966 23 . . . cord-006870-f5w6fw6q 3967 1 Administration Administration NNP cord-006870-f5w6fw6q 3967 2 of of IN cord-006870-f5w6fw6q 3967 3 HTS HTS NNP cord-006870-f5w6fw6q 3967 4 using use VBG cord-006870-f5w6fw6q 3967 5 IO IO NNP cord-006870-f5w6fw6q 3967 6 route route NN cord-006870-f5w6fw6q 3967 7 appears appear VBZ cord-006870-f5w6fw6q 3967 8 to to TO cord-006870-f5w6fw6q 3967 9 be be VB cord-006870-f5w6fw6q 3967 10 safe safe JJ cord-006870-f5w6fw6q 3967 11 and and CC cord-006870-f5w6fw6q 3967 12 feasible feasible JJ cord-006870-f5w6fw6q 3967 13 . . . cord-006870-f5w6fw6q 3968 1 Utilizing utilize VBG cord-006870-f5w6fw6q 3968 2 IO IO NNP cord-006870-f5w6fw6q 3968 3 access access NN cord-006870-f5w6fw6q 3968 4 for for IN cord-006870-f5w6fw6q 3968 5 urgent urgent JJ cord-006870-f5w6fw6q 3968 6 administration administration NN cord-006870-f5w6fw6q 3968 7 of of IN cord-006870-f5w6fw6q 3968 8 HTS HTS NNP cord-006870-f5w6fw6q 3968 9 may may MD cord-006870-f5w6fw6q 3968 10 reduce reduce VB cord-006870-f5w6fw6q 3968 11 the the DT cord-006870-f5w6fw6q 3968 12 lag lag NN cord-006870-f5w6fw6q 3968 13 time time NN cord-006870-f5w6fw6q 3968 14 to to IN cord-006870-f5w6fw6q 3968 15 administration administration NN cord-006870-f5w6fw6q 3968 16 of of IN cord-006870-f5w6fw6q 3968 17 the the DT cord-006870-f5w6fw6q 3968 18 initial initial JJ cord-006870-f5w6fw6q 3968 19 bolus bolus NN cord-006870-f5w6fw6q 3968 20 , , , cord-006870-f5w6fw6q 3968 21 reduce reduce VB cord-006870-f5w6fw6q 3968 22 the the DT cord-006870-f5w6fw6q 3968 23 need need NN cord-006870-f5w6fw6q 3968 24 for for IN cord-006870-f5w6fw6q 3968 25 emergent emergent JJ cord-006870-f5w6fw6q 3968 26 placement placement NN cord-006870-f5w6fw6q 3968 27 or or CC cord-006870-f5w6fw6q 3968 28 eliminate eliminate VB cord-006870-f5w6fw6q 3968 29 the the DT cord-006870-f5w6fw6q 3968 30 placement placement NN cord-006870-f5w6fw6q 3968 31 of of IN cord-006870-f5w6fw6q 3968 32 CVC CVC NNP cord-006870-f5w6fw6q 3968 33 in in IN cord-006870-f5w6fw6q 3968 34 certain certain JJ cord-006870-f5w6fw6q 3968 35 cases case NNS cord-006870-f5w6fw6q 3968 36 . . . cord-006870-f5w6fw6q 3969 1 Optic optic JJ cord-006870-f5w6fw6q 3969 2 nerve nerve NN cord-006870-f5w6fw6q 3969 3 sheath sheath NN cord-006870-f5w6fw6q 3969 4 diameter diameter NN cord-006870-f5w6fw6q 3969 5 ( ( -LRB- cord-006870-f5w6fw6q 3969 6 ONSD ONSD NNP cord-006870-f5w6fw6q 3969 7 ) ) -RRB- cord-006870-f5w6fw6q 3969 8 measurement measurement NN cord-006870-f5w6fw6q 3969 9 is be VBZ cord-006870-f5w6fw6q 3969 10 an an DT cord-006870-f5w6fw6q 3969 11 emerging emerge VBG cord-006870-f5w6fw6q 3969 12 bedside bedside NN cord-006870-f5w6fw6q 3969 13 tool tool NN cord-006870-f5w6fw6q 3969 14 to to TO cord-006870-f5w6fw6q 3969 15 assess assess VB cord-006870-f5w6fw6q 3969 16 intracranial intracranial JJ cord-006870-f5w6fw6q 3969 17 pressure pressure NN cord-006870-f5w6fw6q 3969 18 ( ( -LRB- cord-006870-f5w6fw6q 3969 19 ICP ICP NNP cord-006870-f5w6fw6q 3969 20 ) ) -RRB- cord-006870-f5w6fw6q 3969 21 non non NNS cord-006870-f5w6fw6q 3969 22 - - JJ cord-006870-f5w6fw6q 3969 23 invasively invasively RB cord-006870-f5w6fw6q 3969 24 in in IN cord-006870-f5w6fw6q 3969 25 brain brain NN cord-006870-f5w6fw6q 3969 26 injury injury NN cord-006870-f5w6fw6q 3969 27 patients patient NNS cord-006870-f5w6fw6q 3969 28 . . . cord-006870-f5w6fw6q 3970 1 Multiple multiple JJ cord-006870-f5w6fw6q 3970 2 studies study NNS cord-006870-f5w6fw6q 3970 3 demonstrate demonstrate VBP cord-006870-f5w6fw6q 3970 4 ONSD ONSD NNP cord-006870-f5w6fw6q 3970 5 width width NN cord-006870-f5w6fw6q 3970 6 from from IN cord-006870-f5w6fw6q 3970 7 4.5 4.5 CD cord-006870-f5w6fw6q 3970 8 mm mm CD cord-006870-f5w6fw6q 3970 9 to to IN cord-006870-f5w6fw6q 3970 10 5.8 5.8 CD cord-006870-f5w6fw6q 3970 11 mm mm CD cord-006870-f5w6fw6q 3970 12 correspond correspond VBP cord-006870-f5w6fw6q 3970 13 to to IN cord-006870-f5w6fw6q 3970 14 an an DT cord-006870-f5w6fw6q 3970 15 external external JJ cord-006870-f5w6fw6q 3970 16 ventricular ventricular JJ cord-006870-f5w6fw6q 3970 17 device device NN cord-006870-f5w6fw6q 3970 18 ( ( -LRB- cord-006870-f5w6fw6q 3970 19 EVD)-measured evd)-measured JJ cord-006870-f5w6fw6q 3970 20 ICP ICP NNP cord-006870-f5w6fw6q 3970 21 > > XX cord-006870-f5w6fw6q 3971 1 20mmHg 20mmhg CD cord-006870-f5w6fw6q 3971 2 . . . cord-006870-f5w6fw6q 3972 1 We -PRON- PRP cord-006870-f5w6fw6q 3972 2 sought seek VBD cord-006870-f5w6fw6q 3972 3 to to TO cord-006870-f5w6fw6q 3972 4 create create VB cord-006870-f5w6fw6q 3972 5 a a DT cord-006870-f5w6fw6q 3972 6 low low JJ cord-006870-f5w6fw6q 3972 7 cost cost NN cord-006870-f5w6fw6q 3972 8 , , , cord-006870-f5w6fw6q 3972 9 3-D 3-D NNP cord-006870-f5w6fw6q 3972 10 constructed construct VBN cord-006870-f5w6fw6q 3972 11 , , , cord-006870-f5w6fw6q 3972 12 re re JJ cord-006870-f5w6fw6q 3972 13 - - JJ cord-006870-f5w6fw6q 3972 14 usable usable JJ cord-006870-f5w6fw6q 3972 15 OSND OSND NNP cord-006870-f5w6fw6q 3972 16 teaching teaching NN cord-006870-f5w6fw6q 3972 17 model model NN cord-006870-f5w6fw6q 3972 18 to to TO cord-006870-f5w6fw6q 3972 19 train train VB cord-006870-f5w6fw6q 3972 20 neurology neurology NN cord-006870-f5w6fw6q 3972 21 , , , cord-006870-f5w6fw6q 3972 22 neurosurgery neurosurgery NN cord-006870-f5w6fw6q 3972 23 , , , cord-006870-f5w6fw6q 3972 24 and and CC cord-006870-f5w6fw6q 3972 25 critical critical JJ cord-006870-f5w6fw6q 3972 26 care care NN cord-006870-f5w6fw6q 3972 27 advanced advanced JJ cord-006870-f5w6fw6q 3972 28 practice practice NN cord-006870-f5w6fw6q 3972 29 providers provider NNS cord-006870-f5w6fw6q 3972 30 and and CC cord-006870-f5w6fw6q 3972 31 physicians physician NNS cord-006870-f5w6fw6q 3972 32 . . . cord-006870-f5w6fw6q 3973 1 We -PRON- PRP cord-006870-f5w6fw6q 3973 2 searched search VBD cord-006870-f5w6fw6q 3973 3 the the DT cord-006870-f5w6fw6q 3973 4 National National NNP cord-006870-f5w6fw6q 3973 5 Library Library NNP cord-006870-f5w6fw6q 3973 6 of of IN cord-006870-f5w6fw6q 3973 7 Medicine Medicine NNP cord-006870-f5w6fw6q 3973 8 using use VBG cord-006870-f5w6fw6q 3973 9 terms term NNS cord-006870-f5w6fw6q 3973 10 " " `` cord-006870-f5w6fw6q 3973 11 optic optic JJ cord-006870-f5w6fw6q 3973 12 nerve nerve NN cord-006870-f5w6fw6q 3973 13 sheath sheath NN cord-006870-f5w6fw6q 3973 14 diameter diameter NN cord-006870-f5w6fw6q 3973 15 ultrasound ultrasound NN cord-006870-f5w6fw6q 3973 16 " " '' cord-006870-f5w6fw6q 3973 17 with with IN cord-006870-f5w6fw6q 3973 18 combinations combination NNS cord-006870-f5w6fw6q 3973 19 of of IN cord-006870-f5w6fw6q 3973 20 " " `` cord-006870-f5w6fw6q 3973 21 simulation simulation NN cord-006870-f5w6fw6q 3973 22 " " '' cord-006870-f5w6fw6q 3973 23 and and CC cord-006870-f5w6fw6q 3973 24 " " `` cord-006870-f5w6fw6q 3973 25 model model NN cord-006870-f5w6fw6q 3973 26 . . . cord-006870-f5w6fw6q 3973 27 " " '' cord-006870-f5w6fw6q 3974 1 The the DT cord-006870-f5w6fw6q 3974 2 literature literature NN cord-006870-f5w6fw6q 3974 3 was be VBD cord-006870-f5w6fw6q 3974 4 used use VBN cord-006870-f5w6fw6q 3974 5 in in IN cord-006870-f5w6fw6q 3974 6 conjunction conjunction NN cord-006870-f5w6fw6q 3974 7 with with IN cord-006870-f5w6fw6q 3974 8 a a DT cord-006870-f5w6fw6q 3974 9 human human JJ cord-006870-f5w6fw6q 3974 10 non non JJ cord-006870-f5w6fw6q 3974 11 - - JJ cord-006870-f5w6fw6q 3974 12 contrast contrast JJ cord-006870-f5w6fw6q 3974 13 head head NN cord-006870-f5w6fw6q 3974 14 CT CT NNP cord-006870-f5w6fw6q 3974 15 head head NN cord-006870-f5w6fw6q 3974 16 model model NN cord-006870-f5w6fw6q 3974 17 to to TO cord-006870-f5w6fw6q 3974 18 make make VB cord-006870-f5w6fw6q 3974 19 an an DT cord-006870-f5w6fw6q 3974 20 eye eye NN cord-006870-f5w6fw6q 3974 21 ball ball NN cord-006870-f5w6fw6q 3974 22 model model NN cord-006870-f5w6fw6q 3974 23 which which WDT cord-006870-f5w6fw6q 3974 24 was be VBD cord-006870-f5w6fw6q 3974 25 then then RB cord-006870-f5w6fw6q 3974 26 tested test VBN cord-006870-f5w6fw6q 3974 27 in in IN cord-006870-f5w6fw6q 3974 28 our -PRON- PRP$ cord-006870-f5w6fw6q 3974 29 simulation simulation NN cord-006870-f5w6fw6q 3974 30 center center NN cord-006870-f5w6fw6q 3974 31 and and CC cord-006870-f5w6fw6q 3974 32 compared compare VBN cord-006870-f5w6fw6q 3974 33 to to IN cord-006870-f5w6fw6q 3974 34 a a DT cord-006870-f5w6fw6q 3974 35 live live JJ cord-006870-f5w6fw6q 3974 36 human human JJ cord-006870-f5w6fw6q 3974 37 model model NN cord-006870-f5w6fw6q 3974 38 . . . cord-006870-f5w6fw6q 3975 1 We -PRON- PRP cord-006870-f5w6fw6q 3975 2 identified identify VBD cord-006870-f5w6fw6q 3975 3 253 253 CD cord-006870-f5w6fw6q 3975 4 articles article NNS cord-006870-f5w6fw6q 3975 5 , , , cord-006870-f5w6fw6q 3975 6 of of IN cord-006870-f5w6fw6q 3975 7 which which WDT cord-006870-f5w6fw6q 3975 8 15 15 CD cord-006870-f5w6fw6q 3975 9 were be VBD cord-006870-f5w6fw6q 3975 10 associated associate VBN cord-006870-f5w6fw6q 3975 11 with with IN cord-006870-f5w6fw6q 3975 12 models model NNS cord-006870-f5w6fw6q 3975 13 and and CC cord-006870-f5w6fw6q 3975 14 two two CD cord-006870-f5w6fw6q 3975 15 with with IN cord-006870-f5w6fw6q 3975 16 simulation simulation NN cord-006870-f5w6fw6q 3975 17 . . . cord-006870-f5w6fw6q 3976 1 One one CD cord-006870-f5w6fw6q 3976 2 gelatin gelatin NN cord-006870-f5w6fw6q 3976 3 model model NN cord-006870-f5w6fw6q 3976 4 was be VBD cord-006870-f5w6fw6q 3976 5 reported report VBN cord-006870-f5w6fw6q 3976 6 , , , cord-006870-f5w6fw6q 3976 7 upon upon IN cord-006870-f5w6fw6q 3976 8 which which WDT cord-006870-f5w6fw6q 3976 9 we -PRON- PRP cord-006870-f5w6fw6q 3976 10 based base VBD cord-006870-f5w6fw6q 3976 11 our -PRON- PRP$ cord-006870-f5w6fw6q 3976 12 initial initial JJ cord-006870-f5w6fw6q 3976 13 design design NN cord-006870-f5w6fw6q 3976 14 . . . cord-006870-f5w6fw6q 3977 1 We -PRON- PRP cord-006870-f5w6fw6q 3977 2 could could MD cord-006870-f5w6fw6q 3977 3 not not RB cord-006870-f5w6fw6q 3977 4 validate validate VB cord-006870-f5w6fw6q 3977 5 the the DT cord-006870-f5w6fw6q 3977 6 visual visual JJ cord-006870-f5w6fw6q 3977 7 findings finding NNS cord-006870-f5w6fw6q 3977 8 of of IN cord-006870-f5w6fw6q 3977 9 this this DT cord-006870-f5w6fw6q 3977 10 model model NN cord-006870-f5w6fw6q 3977 11 . . . cord-006870-f5w6fw6q 3978 1 However however RB cord-006870-f5w6fw6q 3978 2 , , , cord-006870-f5w6fw6q 3978 3 following follow VBG cord-006870-f5w6fw6q 3978 4 construction construction NN cord-006870-f5w6fw6q 3978 5 of of IN cord-006870-f5w6fw6q 3978 6 multiple multiple JJ cord-006870-f5w6fw6q 3978 7 beta beta NN cord-006870-f5w6fw6q 3978 8 models model NNS cord-006870-f5w6fw6q 3978 9 , , , cord-006870-f5w6fw6q 3978 10 the the DT cord-006870-f5w6fw6q 3978 11 design design NN cord-006870-f5w6fw6q 3978 12 most most RBS cord-006870-f5w6fw6q 3978 13 representative representative NN cord-006870-f5w6fw6q 3978 14 of of IN cord-006870-f5w6fw6q 3978 15 human human JJ cord-006870-f5w6fw6q 3978 16 eye eye NN cord-006870-f5w6fw6q 3978 17 anatomy anatomy NN cord-006870-f5w6fw6q 3978 18 was be VBD cord-006870-f5w6fw6q 3978 19 a a DT cord-006870-f5w6fw6q 3978 20 globe globe NN cord-006870-f5w6fw6q 3978 21 made make VBN cord-006870-f5w6fw6q 3978 22 of of IN cord-006870-f5w6fw6q 3978 23 ballistics ballistic NNS cord-006870-f5w6fw6q 3978 24 gel gel NN cord-006870-f5w6fw6q 3978 25 with with IN cord-006870-f5w6fw6q 3978 26 either either CC cord-006870-f5w6fw6q 3978 27 a a DT cord-006870-f5w6fw6q 3978 28 3 3 CD cord-006870-f5w6fw6q 3978 29 mm mm NN cord-006870-f5w6fw6q 3978 30 , , , cord-006870-f5w6fw6q 3978 31 5 5 CD cord-006870-f5w6fw6q 3978 32 mm mm NNS cord-006870-f5w6fw6q 3978 33 or or CC cord-006870-f5w6fw6q 3978 34 7 7 CD cord-006870-f5w6fw6q 3978 35 mm mm NN cord-006870-f5w6fw6q 3979 1 3-D 3-D NNP cord-006870-f5w6fw6q 3979 2 printed print VBD cord-006870-f5w6fw6q 3979 3 " " `` cord-006870-f5w6fw6q 3979 4 optic optic JJ cord-006870-f5w6fw6q 3979 5 nerve nerve NN cord-006870-f5w6fw6q 3979 6 " " '' cord-006870-f5w6fw6q 3979 7 attached attach VBN cord-006870-f5w6fw6q 3979 8 to to IN cord-006870-f5w6fw6q 3979 9 a a DT cord-006870-f5w6fw6q 3979 10 platform platform NN cord-006870-f5w6fw6q 3979 11 composed compose VBN cord-006870-f5w6fw6q 3979 12 of of IN cord-006870-f5w6fw6q 3979 13 ballistics ballistic NNS cord-006870-f5w6fw6q 3979 14 gel gel NN cord-006870-f5w6fw6q 3979 15 and and CC cord-006870-f5w6fw6q 3979 16 psyllium psyllium NN cord-006870-f5w6fw6q 3979 17 powder powder NN cord-006870-f5w6fw6q 3979 18 with with IN cord-006870-f5w6fw6q 3979 19 a a DT cord-006870-f5w6fw6q 3979 20 hollowed hollowed JJ cord-006870-f5w6fw6q 3979 21 out out RP cord-006870-f5w6fw6q 3979 22 core core NN cord-006870-f5w6fw6q 3979 23 for for IN cord-006870-f5w6fw6q 3979 24 ultrasound ultrasound NN cord-006870-f5w6fw6q 3979 25 gel gel NN cord-006870-f5w6fw6q 3979 26 the the DT cord-006870-f5w6fw6q 3979 27 globe globe NN cord-006870-f5w6fw6q 3979 28 rests rest VBZ cord-006870-f5w6fw6q 3979 29 upon upon IN cord-006870-f5w6fw6q 3979 30 . . . cord-006870-f5w6fw6q 3980 1 This this DT cord-006870-f5w6fw6q 3980 2 model model NN cord-006870-f5w6fw6q 3980 3 was be VBD cord-006870-f5w6fw6q 3980 4 taught teach VBN cord-006870-f5w6fw6q 3980 5 to to IN cord-006870-f5w6fw6q 3980 6 learners learner NNS cord-006870-f5w6fw6q 3980 7 at at IN cord-006870-f5w6fw6q 3980 8 a a DT cord-006870-f5w6fw6q 3980 9 continuing continue VBG cord-006870-f5w6fw6q 3980 10 medical medical JJ cord-006870-f5w6fw6q 3980 11 education education NN cord-006870-f5w6fw6q 3980 12 event event NN cord-006870-f5w6fw6q 3980 13 prior prior RB cord-006870-f5w6fw6q 3980 14 to to IN cord-006870-f5w6fw6q 3980 15 teaching teach VBG cord-006870-f5w6fw6q 3980 16 OSND OSND NNP cord-006870-f5w6fw6q 3980 17 on on IN cord-006870-f5w6fw6q 3980 18 a a DT cord-006870-f5w6fw6q 3980 19 live live JJ cord-006870-f5w6fw6q 3980 20 human human JJ cord-006870-f5w6fw6q 3980 21 model model NN cord-006870-f5w6fw6q 3980 22 . . . cord-006870-f5w6fw6q 3981 1 A a DT cord-006870-f5w6fw6q 3981 2 3-D 3-d JJ cord-006870-f5w6fw6q 3981 3 printed print VBN cord-006870-f5w6fw6q 3981 4 skull skull NN cord-006870-f5w6fw6q 3981 5 from from IN cord-006870-f5w6fw6q 3981 6 CT CT NNP cord-006870-f5w6fw6q 3981 7 head head NN cord-006870-f5w6fw6q 3981 8 data datum NNS cord-006870-f5w6fw6q 3981 9 is be VBZ cord-006870-f5w6fw6q 3981 10 being be VBG cord-006870-f5w6fw6q 3981 11 created create VBN cord-006870-f5w6fw6q 3981 12 to to TO cord-006870-f5w6fw6q 3981 13 incorporate incorporate VB cord-006870-f5w6fw6q 3981 14 this this DT cord-006870-f5w6fw6q 3981 15 model model NN cord-006870-f5w6fw6q 3981 16 . . . cord-006870-f5w6fw6q 3982 1 A a DT cord-006870-f5w6fw6q 3982 2 simple simple JJ cord-006870-f5w6fw6q 3982 3 3-D 3-d JJ cord-006870-f5w6fw6q 3982 4 ballistic ballistic JJ cord-006870-f5w6fw6q 3982 5 ONSD ONSD NNP cord-006870-f5w6fw6q 3982 6 model model NN cord-006870-f5w6fw6q 3982 7 allows allow VBZ cord-006870-f5w6fw6q 3982 8 learners learner NNS cord-006870-f5w6fw6q 3982 9 to to TO cord-006870-f5w6fw6q 3982 10 learn learn VB cord-006870-f5w6fw6q 3982 11 proper proper JJ cord-006870-f5w6fw6q 3982 12 hand hand NN cord-006870-f5w6fw6q 3982 13 placement placement NN cord-006870-f5w6fw6q 3982 14 , , , cord-006870-f5w6fw6q 3982 15 basic basic JJ cord-006870-f5w6fw6q 3982 16 landmarks landmark NNS cord-006870-f5w6fw6q 3982 17 , , , cord-006870-f5w6fw6q 3982 18 ONSD ONSD NNP cord-006870-f5w6fw6q 3982 19 measurement measurement NN cord-006870-f5w6fw6q 3982 20 , , , cord-006870-f5w6fw6q 3982 21 and and CC cord-006870-f5w6fw6q 3982 22 practice practice VB cord-006870-f5w6fw6q 3982 23 proper proper JJ cord-006870-f5w6fw6q 3982 24 pressure pressure NN cord-006870-f5w6fw6q 3982 25 on on IN cord-006870-f5w6fw6q 3982 26 human human JJ cord-006870-f5w6fw6q 3982 27 eyes eye NNS cord-006870-f5w6fw6q 3982 28 . . . cord-006870-f5w6fw6q 3983 1 This this DT cord-006870-f5w6fw6q 3983 2 model model NN cord-006870-f5w6fw6q 3983 3 can can MD cord-006870-f5w6fw6q 3983 4 be be VB cord-006870-f5w6fw6q 3983 5 replicated replicate VBN cord-006870-f5w6fw6q 3983 6 and and CC cord-006870-f5w6fw6q 3983 7 utilized utilize VBN cord-006870-f5w6fw6q 3983 8 in in IN cord-006870-f5w6fw6q 3983 9 a a DT cord-006870-f5w6fw6q 3983 10 sustainable sustainable JJ cord-006870-f5w6fw6q 3983 11 fashion fashion NN cord-006870-f5w6fw6q 3983 12 given give VBN cord-006870-f5w6fw6q 3983 13 that that IN cord-006870-f5w6fw6q 3983 14 the the DT cord-006870-f5w6fw6q 3983 15 globe globe NN cord-006870-f5w6fw6q 3983 16 and and CC cord-006870-f5w6fw6q 3983 17 platform platform NN cord-006870-f5w6fw6q 3983 18 are be VBP cord-006870-f5w6fw6q 3983 19 composed compose VBN cord-006870-f5w6fw6q 3983 20 of of IN cord-006870-f5w6fw6q 3983 21 ballistics ballistic NNS cord-006870-f5w6fw6q 3983 22 gel gel NN cord-006870-f5w6fw6q 3983 23 . . . cord-006870-f5w6fw6q 3984 1 Pressure pressure NN cord-006870-f5w6fw6q 3984 2 measurements measurement NNS cord-006870-f5w6fw6q 3984 3 using use VBG cord-006870-f5w6fw6q 3984 4 pressure pressure NN cord-006870-f5w6fw6q 3984 5 guide guide NN cord-006870-f5w6fw6q 3984 6 wires wire NNS cord-006870-f5w6fw6q 3984 7 is be VBZ cord-006870-f5w6fw6q 3984 8 an an DT cord-006870-f5w6fw6q 3984 9 invaluable invaluable JJ cord-006870-f5w6fw6q 3984 10 diagnostic diagnostic JJ cord-006870-f5w6fw6q 3984 11 tool tool NN cord-006870-f5w6fw6q 3984 12 in in IN cord-006870-f5w6fw6q 3984 13 the the DT cord-006870-f5w6fw6q 3984 14 management management NN cord-006870-f5w6fw6q 3984 15 of of IN cord-006870-f5w6fw6q 3984 16 many many JJ cord-006870-f5w6fw6q 3984 17 endovascular endovascular JJ cord-006870-f5w6fw6q 3984 18 revascularization revascularization NN cord-006870-f5w6fw6q 3984 19 therapies therapy NNS cord-006870-f5w6fw6q 3984 20 . . . cord-006870-f5w6fw6q 3985 1 Its -PRON- PRP$ cord-006870-f5w6fw6q 3985 2 role role NN cord-006870-f5w6fw6q 3985 3 is be VBZ cord-006870-f5w6fw6q 3985 4 well well RB cord-006870-f5w6fw6q 3985 5 established establish VBN cord-006870-f5w6fw6q 3985 6 in in IN cord-006870-f5w6fw6q 3985 7 coronary coronary JJ cord-006870-f5w6fw6q 3985 8 artery artery NN cord-006870-f5w6fw6q 3985 9 disease disease NN cord-006870-f5w6fw6q 3985 10 management management NN cord-006870-f5w6fw6q 3985 11 such such JJ cord-006870-f5w6fw6q 3985 12 as as IN cord-006870-f5w6fw6q 3985 13 use use NN cord-006870-f5w6fw6q 3985 14 of of IN cord-006870-f5w6fw6q 3985 15 fractional fractional JJ cord-006870-f5w6fw6q 3985 16 flow flow NN cord-006870-f5w6fw6q 3985 17 reserve reserve NN cord-006870-f5w6fw6q 3985 18 ( ( -LRB- cord-006870-f5w6fw6q 3985 19 FFR FFR NNP cord-006870-f5w6fw6q 3985 20 ) ) -RRB- cord-006870-f5w6fw6q 3985 21 as as IN cord-006870-f5w6fw6q 3985 22 a a DT cord-006870-f5w6fw6q 3985 23 standard standard JJ cord-006870-f5w6fw6q 3985 24 diagnostic diagnostic JJ cord-006870-f5w6fw6q 3985 25 tool tool NN cord-006870-f5w6fw6q 3985 26 to to TO cord-006870-f5w6fw6q 3985 27 determine determine VB cord-006870-f5w6fw6q 3985 28 need need NN cord-006870-f5w6fw6q 3985 29 for for IN cord-006870-f5w6fw6q 3985 30 stenting stenting NN cord-006870-f5w6fw6q 3985 31 , , , cord-006870-f5w6fw6q 3985 32 angioplasty angioplasty NN cord-006870-f5w6fw6q 3985 33 or or CC cord-006870-f5w6fw6q 3985 34 bypass bypass NN cord-006870-f5w6fw6q 3985 35 . . . cord-006870-f5w6fw6q 3986 1 Renal renal JJ cord-006870-f5w6fw6q 3986 2 fractional fractional JJ cord-006870-f5w6fw6q 3986 3 flow flow NN cord-006870-f5w6fw6q 3986 4 reserve reserve NN cord-006870-f5w6fw6q 3986 5 remains remain VBZ cord-006870-f5w6fw6q 3986 6 an an DT cord-006870-f5w6fw6q 3986 7 integral integral JJ cord-006870-f5w6fw6q 3986 8 physiologic physiologic JJ cord-006870-f5w6fw6q 3986 9 parameter parameter NN cord-006870-f5w6fw6q 3986 10 used use VBN cord-006870-f5w6fw6q 3986 11 in in IN cord-006870-f5w6fw6q 3986 12 endovascular endovascular JJ cord-006870-f5w6fw6q 3986 13 revascularization revascularization NN cord-006870-f5w6fw6q 3986 14 therapy therapy NN cord-006870-f5w6fw6q 3986 15 of of IN cord-006870-f5w6fw6q 3986 16 renal renal JJ cord-006870-f5w6fw6q 3986 17 artery artery NN cord-006870-f5w6fw6q 3986 18 stenosis stenosis NN cord-006870-f5w6fw6q 3986 19 . . . cord-006870-f5w6fw6q 3987 1 Despite despite IN cord-006870-f5w6fw6q 3987 2 the the DT cord-006870-f5w6fw6q 3987 3 wide wide JJ cord-006870-f5w6fw6q 3987 4 spread spread NN cord-006870-f5w6fw6q 3987 5 use use NN cord-006870-f5w6fw6q 3987 6 of of IN cord-006870-f5w6fw6q 3987 7 pressure pressure NN cord-006870-f5w6fw6q 3987 8 wires wire NNS cord-006870-f5w6fw6q 3987 9 in in IN cord-006870-f5w6fw6q 3987 10 endovascular endovascular JJ cord-006870-f5w6fw6q 3987 11 therapies therapy NNS cord-006870-f5w6fw6q 3987 12 , , , cord-006870-f5w6fw6q 3987 13 its -PRON- PRP$ cord-006870-f5w6fw6q 3987 14 application application NN cord-006870-f5w6fw6q 3987 15 in in IN cord-006870-f5w6fw6q 3987 16 the the DT cord-006870-f5w6fw6q 3987 17 management management NN cord-006870-f5w6fw6q 3987 18 of of IN cord-006870-f5w6fw6q 3987 19 cerebral cerebral JJ cord-006870-f5w6fw6q 3987 20 venous venous JJ cord-006870-f5w6fw6q 3987 21 diseases disease NNS cord-006870-f5w6fw6q 3987 22 remains remain VBZ cord-006870-f5w6fw6q 3987 23 vastly vastly RB cord-006870-f5w6fw6q 3987 24 unexplored unexplored JJ cord-006870-f5w6fw6q 3987 25 . . . cord-006870-f5w6fw6q 3988 1 We -PRON- PRP cord-006870-f5w6fw6q 3988 2 sought seek VBD cord-006870-f5w6fw6q 3988 3 to to TO cord-006870-f5w6fw6q 3988 4 evaluate evaluate VB cord-006870-f5w6fw6q 3988 5 the the DT cord-006870-f5w6fw6q 3988 6 safety safety NN cord-006870-f5w6fw6q 3988 7 and and CC cord-006870-f5w6fw6q 3988 8 applicability applicability NN cord-006870-f5w6fw6q 3988 9 of of IN cord-006870-f5w6fw6q 3988 10 pressure pressure NN cord-006870-f5w6fw6q 3988 11 guide guide NN cord-006870-f5w6fw6q 3988 12 wires wire NNS cord-006870-f5w6fw6q 3988 13 in in IN cord-006870-f5w6fw6q 3988 14 several several JJ cord-006870-f5w6fw6q 3988 15 cerebral cerebral JJ cord-006870-f5w6fw6q 3988 16 venous venous JJ cord-006870-f5w6fw6q 3988 17 diseases disease NNS cord-006870-f5w6fw6q 3988 18 . . . cord-006870-f5w6fw6q 3989 1 Patients patient NNS cord-006870-f5w6fw6q 3989 2 undergoing undergo VBG cord-006870-f5w6fw6q 3989 3 diagnostic diagnostic JJ cord-006870-f5w6fw6q 3989 4 angiography angiography NN cord-006870-f5w6fw6q 3989 5 for for IN cord-006870-f5w6fw6q 3989 6 possible possible JJ cord-006870-f5w6fw6q 3989 7 venous venous JJ cord-006870-f5w6fw6q 3989 8 outflow outflow JJ cord-006870-f5w6fw6q 3989 9 obstruction obstruction NN cord-006870-f5w6fw6q 3989 10 had have VBD cord-006870-f5w6fw6q 3989 11 pressures pressure NNS cord-006870-f5w6fw6q 3989 12 measured measure VBN cord-006870-f5w6fw6q 3989 13 by by IN cord-006870-f5w6fw6q 3989 14 pressure pressure NN cord-006870-f5w6fw6q 3989 15 guide guide NN cord-006870-f5w6fw6q 3989 16 wires wire NNS cord-006870-f5w6fw6q 3990 1 ( ( -LRB- cord-006870-f5w6fw6q 3990 2 Volcano Volcano NNP cord-006870-f5w6fw6q 3990 3 Verrata Verrata NNP cord-006870-f5w6fw6q 3990 4 ® ® VBP cord-006870-f5w6fw6q 3990 5 or or CC cord-006870-f5w6fw6q 3991 1 Prestige Prestige NNP cord-006870-f5w6fw6q 3991 2 PrimeWire PrimeWire NNP cord-006870-f5w6fw6q 3992 1 ® ® LS cord-006870-f5w6fw6q 3992 2 ) ) -RRB- cord-006870-f5w6fw6q 3992 3 across across IN cord-006870-f5w6fw6q 3992 4 the the DT cord-006870-f5w6fw6q 3992 5 following follow VBG cord-006870-f5w6fw6q 3992 6 vessels vessel NNS cord-006870-f5w6fw6q 3992 7 : : : cord-006870-f5w6fw6q 3992 8 superior superior JJ cord-006870-f5w6fw6q 3992 9 sagittal sagittal JJ cord-006870-f5w6fw6q 3992 10 sinus sinus NN cord-006870-f5w6fw6q 3992 11 , , , cord-006870-f5w6fw6q 3992 12 torcula torcula NNP cord-006870-f5w6fw6q 3992 13 , , , cord-006870-f5w6fw6q 3992 14 right right UH cord-006870-f5w6fw6q 3992 15 and and CC cord-006870-f5w6fw6q 3992 16 left leave VBD cord-006870-f5w6fw6q 3992 17 transverse transverse JJ cord-006870-f5w6fw6q 3992 18 sinus sinus NN cord-006870-f5w6fw6q 3992 19 , , , cord-006870-f5w6fw6q 3992 20 right right UH cord-006870-f5w6fw6q 3992 21 and and CC cord-006870-f5w6fw6q 3992 22 left left JJ cord-006870-f5w6fw6q 3992 23 sigmoid sigmoid JJ cord-006870-f5w6fw6q 3992 24 sinus sinus NN cord-006870-f5w6fw6q 3992 25 , , , cord-006870-f5w6fw6q 3992 26 and and CC cord-006870-f5w6fw6q 3992 27 right right UH cord-006870-f5w6fw6q 3992 28 and and CC cord-006870-f5w6fw6q 3992 29 left leave VBD cord-006870-f5w6fw6q 3992 30 internal internal JJ cord-006870-f5w6fw6q 3992 31 jugular jugular NN cord-006870-f5w6fw6q 3992 32 vein vein NN cord-006870-f5w6fw6q 3992 33 . . . cord-006870-f5w6fw6q 3993 1 Venous venous JJ cord-006870-f5w6fw6q 3993 2 pressures pressure NNS cord-006870-f5w6fw6q 3993 3 were be VBD cord-006870-f5w6fw6q 3993 4 also also RB cord-006870-f5w6fw6q 3993 5 collected collect VBN cord-006870-f5w6fw6q 3993 6 from from IN cord-006870-f5w6fw6q 3993 7 patients patient NNS cord-006870-f5w6fw6q 3993 8 undergoing undergo VBG cord-006870-f5w6fw6q 3993 9 venous venous JJ cord-006870-f5w6fw6q 3993 10 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 3993 11 , , , cord-006870-f5w6fw6q 3993 12 stenting stenting NN cord-006870-f5w6fw6q 3993 13 , , , cord-006870-f5w6fw6q 3993 14 or or CC cord-006870-f5w6fw6q 3993 15 an an DT cord-006870-f5w6fw6q 3993 16 arteriovenous arteriovenous JJ cord-006870-f5w6fw6q 3993 17 malformation malformation NN cord-006870-f5w6fw6q 3993 18 embolization embolization NN cord-006870-f5w6fw6q 3993 19 ( ( -LRB- cord-006870-f5w6fw6q 3993 20 AVM AVM NNP cord-006870-f5w6fw6q 3993 21 ) ) -RRB- cord-006870-f5w6fw6q 3993 22 . . . cord-006870-f5w6fw6q 3994 1 Five five CD cord-006870-f5w6fw6q 3994 2 patients patient NNS cord-006870-f5w6fw6q 3994 3 who who WP cord-006870-f5w6fw6q 3994 4 underwent undergo VBD cord-006870-f5w6fw6q 3994 5 diagnostic diagnostic JJ cord-006870-f5w6fw6q 3994 6 angiography angiography NN cord-006870-f5w6fw6q 3994 7 for for IN cord-006870-f5w6fw6q 3994 8 pseudotumor pseudotumor NN cord-006870-f5w6fw6q 3994 9 cerebri cerebri NNP cord-006870-f5w6fw6q 3994 10 showed show VBD cord-006870-f5w6fw6q 3994 11 no no DT cord-006870-f5w6fw6q 3994 12 major major JJ cord-006870-f5w6fw6q 3994 13 variability variability NN cord-006870-f5w6fw6q 3994 14 in in IN cord-006870-f5w6fw6q 3994 15 their -PRON- PRP$ cord-006870-f5w6fw6q 3994 16 pressures pressure NNS cord-006870-f5w6fw6q 3994 17 across across IN cord-006870-f5w6fw6q 3994 18 the the DT cord-006870-f5w6fw6q 3994 19 cerebral cerebral JJ cord-006870-f5w6fw6q 3994 20 venous venous JJ cord-006870-f5w6fw6q 3994 21 architecture architecture NN cord-006870-f5w6fw6q 3994 22 which which WDT cord-006870-f5w6fw6q 3994 23 was be VBD cord-006870-f5w6fw6q 3994 24 confirmed confirm VBN cord-006870-f5w6fw6q 3994 25 by by IN cord-006870-f5w6fw6q 3994 26 lack lack NN cord-006870-f5w6fw6q 3994 27 of of IN cord-006870-f5w6fw6q 3994 28 stenosis stenosis NN cord-006870-f5w6fw6q 3994 29 or or CC cord-006870-f5w6fw6q 3994 30 thrombi thrombi NN cord-006870-f5w6fw6q 3994 31 on on IN cord-006870-f5w6fw6q 3994 32 intravascular intravascular JJ cord-006870-f5w6fw6q 3994 33 ultrasound ultrasound NN cord-006870-f5w6fw6q 3994 34 ( ( -LRB- cord-006870-f5w6fw6q 3994 35 IVUS IVUS NNP cord-006870-f5w6fw6q 3994 36 ) ) -RRB- cord-006870-f5w6fw6q 3994 37 . . . cord-006870-f5w6fw6q 3995 1 Four four CD cord-006870-f5w6fw6q 3995 2 patients patient NNS cord-006870-f5w6fw6q 3995 3 had have VBD cord-006870-f5w6fw6q 3995 4 a a DT cord-006870-f5w6fw6q 3995 5 pressure pressure NN cord-006870-f5w6fw6q 3995 6 difference difference NN cord-006870-f5w6fw6q 3995 7 above above IN cord-006870-f5w6fw6q 3995 8 10 10 CD cord-006870-f5w6fw6q 3995 9 which which WDT cord-006870-f5w6fw6q 3995 10 was be VBD cord-006870-f5w6fw6q 3995 11 suggestive suggestive JJ cord-006870-f5w6fw6q 3995 12 of of IN cord-006870-f5w6fw6q 3995 13 a a DT cord-006870-f5w6fw6q 3995 14 stenosis stenosis NN cord-006870-f5w6fw6q 3995 15 and and CC cord-006870-f5w6fw6q 3995 16 later later RB cord-006870-f5w6fw6q 3995 17 confirmed confirm VBN cord-006870-f5w6fw6q 3995 18 by by IN cord-006870-f5w6fw6q 3995 19 IVUS IVUS NNP cord-006870-f5w6fw6q 3995 20 . . . cord-006870-f5w6fw6q 3996 1 Patients patient NNS cord-006870-f5w6fw6q 3996 2 undergoing undergo VBG cord-006870-f5w6fw6q 3996 3 pressure pressure NN cord-006870-f5w6fw6q 3996 4 measurements measurement NNS cord-006870-f5w6fw6q 3996 5 that that WDT cord-006870-f5w6fw6q 3996 6 had have VBD cord-006870-f5w6fw6q 3996 7 evidence evidence NN cord-006870-f5w6fw6q 3996 8 of of IN cord-006870-f5w6fw6q 3996 9 stenosis stenosis NN cord-006870-f5w6fw6q 3996 10 or or CC cord-006870-f5w6fw6q 3996 11 thrombosis thrombosis NN cord-006870-f5w6fw6q 3996 12 by by IN cord-006870-f5w6fw6q 3996 13 IVUS IVUS NNP cord-006870-f5w6fw6q 3997 1 showed show VBD cord-006870-f5w6fw6q 3997 2 improvement improvement NN cord-006870-f5w6fw6q 3997 3 in in IN cord-006870-f5w6fw6q 3997 4 pressure pressure NN cord-006870-f5w6fw6q 3997 5 gradients gradient NNS cord-006870-f5w6fw6q 3997 6 post post VBP cord-006870-f5w6fw6q 3997 7 stenting stenting NN cord-006870-f5w6fw6q 3997 8 or or CC cord-006870-f5w6fw6q 3997 9 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 3997 10 . . . cord-006870-f5w6fw6q 3998 1 No no DT cord-006870-f5w6fw6q 3998 2 variability variability NN cord-006870-f5w6fw6q 3998 3 in in IN cord-006870-f5w6fw6q 3998 4 pressure pressure NN cord-006870-f5w6fw6q 3998 5 gradients gradient NNS cord-006870-f5w6fw6q 3998 6 were be VBD cord-006870-f5w6fw6q 3998 7 noted note VBN cord-006870-f5w6fw6q 3998 8 in in IN cord-006870-f5w6fw6q 3998 9 a a DT cord-006870-f5w6fw6q 3998 10 patient patient NN cord-006870-f5w6fw6q 3998 11 that that WDT cord-006870-f5w6fw6q 3998 12 underwent undergo VBD cord-006870-f5w6fw6q 3998 13 AVM AVM NNP cord-006870-f5w6fw6q 3998 14 embolization embolization NN cord-006870-f5w6fw6q 3998 15 . . . cord-006870-f5w6fw6q 3999 1 Pressure pressure NN cord-006870-f5w6fw6q 3999 2 measurements measurement NNS cord-006870-f5w6fw6q 3999 3 using use VBG cord-006870-f5w6fw6q 3999 4 pressure pressure NN cord-006870-f5w6fw6q 3999 5 guide guide NN cord-006870-f5w6fw6q 3999 6 wires wire NNS cord-006870-f5w6fw6q 3999 7 can can MD cord-006870-f5w6fw6q 3999 8 improve improve VB cord-006870-f5w6fw6q 3999 9 diagnostic diagnostic JJ cord-006870-f5w6fw6q 3999 10 accuracy accuracy NN cord-006870-f5w6fw6q 3999 11 and and CC cord-006870-f5w6fw6q 3999 12 guide guide NN cord-006870-f5w6fw6q 3999 13 management management NN cord-006870-f5w6fw6q 3999 14 of of IN cord-006870-f5w6fw6q 3999 15 several several JJ cord-006870-f5w6fw6q 3999 16 diseases disease NNS cord-006870-f5w6fw6q 3999 17 of of IN cord-006870-f5w6fw6q 3999 18 the the DT cord-006870-f5w6fw6q 3999 19 cerebral cerebral JJ cord-006870-f5w6fw6q 3999 20 venous venous JJ cord-006870-f5w6fw6q 3999 21 system system NN cord-006870-f5w6fw6q 3999 22 . . . cord-006870-f5w6fw6q 4000 1 Further further JJ cord-006870-f5w6fw6q 4000 2 studies study NNS cord-006870-f5w6fw6q 4000 3 are be VBP cord-006870-f5w6fw6q 4000 4 necessary necessary JJ cord-006870-f5w6fw6q 4000 5 to to TO cord-006870-f5w6fw6q 4000 6 understand understand VB cord-006870-f5w6fw6q 4000 7 the the DT cord-006870-f5w6fw6q 4000 8 applicability applicability NN cord-006870-f5w6fw6q 4000 9 of of IN cord-006870-f5w6fw6q 4000 10 this this DT cord-006870-f5w6fw6q 4000 11 approach approach NN cord-006870-f5w6fw6q 4000 12 in in IN cord-006870-f5w6fw6q 4000 13 the the DT cord-006870-f5w6fw6q 4000 14 management management NN cord-006870-f5w6fw6q 4000 15 of of IN cord-006870-f5w6fw6q 4000 16 venous venous JJ cord-006870-f5w6fw6q 4000 17 disease disease NN cord-006870-f5w6fw6q 4000 18 . . . cord-006870-f5w6fw6q 4001 1 Monitoring monitoring NN cord-006870-f5w6fw6q 4001 2 metrics metric NNS cord-006870-f5w6fw6q 4001 3 is be VBZ cord-006870-f5w6fw6q 4001 4 imperative imperative JJ cord-006870-f5w6fw6q 4001 5 for for IN cord-006870-f5w6fw6q 4001 6 quality quality NN cord-006870-f5w6fw6q 4001 7 assurance assurance NN cord-006870-f5w6fw6q 4001 8 and and CC cord-006870-f5w6fw6q 4001 9 ongoing ongoing JJ cord-006870-f5w6fw6q 4001 10 improvement improvement NN cord-006870-f5w6fw6q 4001 11 in in IN cord-006870-f5w6fw6q 4001 12 a a DT cord-006870-f5w6fw6q 4001 13 developing develop VBG cord-006870-f5w6fw6q 4001 14 clinical clinical JJ cord-006870-f5w6fw6q 4001 15 unit unit NN cord-006870-f5w6fw6q 4001 16 . . . cord-006870-f5w6fw6q 4002 1 A a DT cord-006870-f5w6fw6q 4002 2 new new JJ cord-006870-f5w6fw6q 4002 3 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 4002 4 care care NN cord-006870-f5w6fw6q 4002 5 unit unit NN cord-006870-f5w6fw6q 4002 6 ( ( -LRB- cord-006870-f5w6fw6q 4002 7 NCCU NCCU NNP cord-006870-f5w6fw6q 4002 8 ) ) -RRB- cord-006870-f5w6fw6q 4002 9 , , , cord-006870-f5w6fw6q 4002 10 specializing specialize VBG cord-006870-f5w6fw6q 4002 11 in in IN cord-006870-f5w6fw6q 4002 12 the the DT cord-006870-f5w6fw6q 4002 13 treatment treatment NN cord-006870-f5w6fw6q 4002 14 of of IN cord-006870-f5w6fw6q 4002 15 critically critically RB cord-006870-f5w6fw6q 4002 16 ill ill JJ cord-006870-f5w6fw6q 4003 1 , , , cord-006870-f5w6fw6q 4003 2 neurologicallyinjured neurologicallyinjure VBN cord-006870-f5w6fw6q 4003 3 patients patient NNS cord-006870-f5w6fw6q 4003 4 opened open VBD cord-006870-f5w6fw6q 4003 5 in in IN cord-006870-f5w6fw6q 4003 6 July July NNP cord-006870-f5w6fw6q 4003 7 2013 2013 CD cord-006870-f5w6fw6q 4003 8 . . . cord-006870-f5w6fw6q 4004 1 This this DT cord-006870-f5w6fw6q 4004 2 study study NN cord-006870-f5w6fw6q 4004 3 examined examine VBD cord-006870-f5w6fw6q 4004 4 quality quality NN cord-006870-f5w6fw6q 4004 5 metrics metric NNS cord-006870-f5w6fw6q 4004 6 that that WDT cord-006870-f5w6fw6q 4004 7 correlate correlate VBP cord-006870-f5w6fw6q 4004 8 with with IN cord-006870-f5w6fw6q 4004 9 the the DT cord-006870-f5w6fw6q 4004 10 development development NN cord-006870-f5w6fw6q 4004 11 and and CC cord-006870-f5w6fw6q 4004 12 growth growth NN cord-006870-f5w6fw6q 4004 13 of of IN cord-006870-f5w6fw6q 4004 14 a a DT cord-006870-f5w6fw6q 4004 15 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 4004 16 care care NN cord-006870-f5w6fw6q 4004 17 program program NN cord-006870-f5w6fw6q 4004 18 . . . cord-006870-f5w6fw6q 4005 1 Data datum NNS cord-006870-f5w6fw6q 4005 2 from from IN cord-006870-f5w6fw6q 4005 3 patients patient NNS cord-006870-f5w6fw6q 4005 4 with with IN cord-006870-f5w6fw6q 4005 5 principle principle JJ cord-006870-f5w6fw6q 4005 6 diagnoses diagnosis NNS cord-006870-f5w6fw6q 4005 7 of of IN cord-006870-f5w6fw6q 4005 8 ischemic ischemic JJ cord-006870-f5w6fw6q 4005 9 stroke stroke NN cord-006870-f5w6fw6q 4005 10 ( ( -LRB- cord-006870-f5w6fw6q 4005 11 ISC ISC NNP cord-006870-f5w6fw6q 4005 12 ) ) -RRB- cord-006870-f5w6fw6q 4005 13 , , , cord-006870-f5w6fw6q 4005 14 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4005 15 ( ( -LRB- cord-006870-f5w6fw6q 4005 16 SAH SAH NNP cord-006870-f5w6fw6q 4005 17 ) ) -RRB- cord-006870-f5w6fw6q 4005 18 or or CC cord-006870-f5w6fw6q 4005 19 intracerebral intracerebral NNP cord-006870-f5w6fw6q 4005 20 ( ( -LRB- cord-006870-f5w6fw6q 4005 21 ICH ICH NNP cord-006870-f5w6fw6q 4005 22 ) ) -RRB- cord-006870-f5w6fw6q 4005 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4005 24 , , , cord-006870-f5w6fw6q 4005 25 seizure seizure NN cord-006870-f5w6fw6q 4005 26 , , , cord-006870-f5w6fw6q 4005 27 or or CC cord-006870-f5w6fw6q 4005 28 brain brain NN cord-006870-f5w6fw6q 4005 29 tumor tumor NN cord-006870-f5w6fw6q 4005 30 , , , cord-006870-f5w6fw6q 4005 31 admitted admit VBN cord-006870-f5w6fw6q 4005 32 to to IN cord-006870-f5w6fw6q 4005 33 NCCU NCCU NNP cord-006870-f5w6fw6q 4005 34 in in IN cord-006870-f5w6fw6q 4005 35 2014 2014 CD cord-006870-f5w6fw6q 4005 36 and and CC cord-006870-f5w6fw6q 4005 37 2016 2016 CD cord-006870-f5w6fw6q 4005 38 were be VBD cord-006870-f5w6fw6q 4005 39 used use VBN cord-006870-f5w6fw6q 4005 40 in in IN cord-006870-f5w6fw6q 4005 41 the the DT cord-006870-f5w6fw6q 4005 42 analyses analysis NNS cord-006870-f5w6fw6q 4005 43 . . . cord-006870-f5w6fw6q 4006 1 Quality quality NN cord-006870-f5w6fw6q 4006 2 metrics metric NNS cord-006870-f5w6fw6q 4006 3 included include VBD cord-006870-f5w6fw6q 4006 4 overall overall JJ cord-006870-f5w6fw6q 4006 5 and and CC cord-006870-f5w6fw6q 4006 6 individual individual JJ cord-006870-f5w6fw6q 4006 7 complication complication NN cord-006870-f5w6fw6q 4006 8 rates rate NNS cord-006870-f5w6fw6q 4006 9 per per IN cord-006870-f5w6fw6q 4006 10 1,000 1,000 CD cord-006870-f5w6fw6q 4006 11 patient patient JJ cord-006870-f5w6fw6q 4006 12 days day NNS cord-006870-f5w6fw6q 4006 13 of of IN cord-006870-f5w6fw6q 4006 14 pneumonia pneumonia NN cord-006870-f5w6fw6q 4006 15 , , , cord-006870-f5w6fw6q 4006 16 venous venous JJ cord-006870-f5w6fw6q 4006 17 thromboembolism thromboembolism NN cord-006870-f5w6fw6q 4006 18 , , , cord-006870-f5w6fw6q 4006 19 pulmonary pulmonary JJ cord-006870-f5w6fw6q 4006 20 embolism embolism NN cord-006870-f5w6fw6q 4006 21 , , , cord-006870-f5w6fw6q 4006 22 sepsis sepsis NN cord-006870-f5w6fw6q 4006 23 , , , cord-006870-f5w6fw6q 4006 24 septic septic JJ cord-006870-f5w6fw6q 4006 25 shock shock NN cord-006870-f5w6fw6q 4006 26 , , , cord-006870-f5w6fw6q 4006 27 pulmonary pulmonary JJ cord-006870-f5w6fw6q 4006 28 edema edema NN cord-006870-f5w6fw6q 4006 29 , , , cord-006870-f5w6fw6q 4006 30 gastrointestinal gastrointestinal JJ cord-006870-f5w6fw6q 4006 31 bleeding bleeding NN cord-006870-f5w6fw6q 4006 32 , , , cord-006870-f5w6fw6q 4006 33 and and CC cord-006870-f5w6fw6q 4006 34 catheter catheter NN cord-006870-f5w6fw6q 4006 35 associated associate VBD cord-006870-f5w6fw6q 4006 36 urinary urinary JJ cord-006870-f5w6fw6q 4006 37 tract tract NN cord-006870-f5w6fw6q 4006 38 infection infection NN cord-006870-f5w6fw6q 4006 39 , , , cord-006870-f5w6fw6q 4006 40 as as RB cord-006870-f5w6fw6q 4006 41 well well RB cord-006870-f5w6fw6q 4006 42 as as IN cord-006870-f5w6fw6q 4006 43 hospital hospital NN cord-006870-f5w6fw6q 4006 44 mortality mortality NN cord-006870-f5w6fw6q 4006 45 and and CC cord-006870-f5w6fw6q 4006 46 length length NN cord-006870-f5w6fw6q 4006 47 of of IN cord-006870-f5w6fw6q 4006 48 stay stay NN cord-006870-f5w6fw6q 4006 49 ( ( -LRB- cord-006870-f5w6fw6q 4006 50 LOS LOS NNP cord-006870-f5w6fw6q 4006 51 ) ) -RRB- cord-006870-f5w6fw6q 4006 52 . . . cord-006870-f5w6fw6q 4007 1 Chi Chi NNP cord-006870-f5w6fw6q 4007 2 - - HYPH cord-006870-f5w6fw6q 4007 3 squared square VBD cord-006870-f5w6fw6q 4007 4 and and CC cord-006870-f5w6fw6q 4007 5 Mann Mann NNP cord-006870-f5w6fw6q 4007 6 - - HYPH cord-006870-f5w6fw6q 4007 7 Whitney Whitney NNP cord-006870-f5w6fw6q 4007 8 tests test VBZ cord-006870-f5w6fw6q 4007 9 and and CC cord-006870-f5w6fw6q 4007 10 Poisson Poisson NNP cord-006870-f5w6fw6q 4007 11 regression regression NN cord-006870-f5w6fw6q 4007 12 were be VBD cord-006870-f5w6fw6q 4007 13 used use VBN cord-006870-f5w6fw6q 4007 14 to to TO cord-006870-f5w6fw6q 4007 15 compare compare VB cord-006870-f5w6fw6q 4007 16 metrics metric NNS cord-006870-f5w6fw6q 4007 17 between between IN cord-006870-f5w6fw6q 4007 18 2014 2014 CD cord-006870-f5w6fw6q 4007 19 and and CC cord-006870-f5w6fw6q 4007 20 2016 2016 CD cord-006870-f5w6fw6q 4007 21 . . . cord-006870-f5w6fw6q 4008 1 Patient patient JJ cord-006870-f5w6fw6q 4008 2 volumes volume NNS cord-006870-f5w6fw6q 4008 3 increased increase VBD cord-006870-f5w6fw6q 4008 4 by by IN cord-006870-f5w6fw6q 4008 5 17.0 17.0 CD cord-006870-f5w6fw6q 4008 6 % % NN cord-006870-f5w6fw6q 4008 7 ( ( -LRB- cord-006870-f5w6fw6q 4008 8 439 439 CD cord-006870-f5w6fw6q 4008 9 to to IN cord-006870-f5w6fw6q 4008 10 515 515 CD cord-006870-f5w6fw6q 4008 11 ) ) -RRB- cord-006870-f5w6fw6q 4008 12 from from IN cord-006870-f5w6fw6q 4008 13 2014 2014 CD cord-006870-f5w6fw6q 4008 14 to to IN cord-006870-f5w6fw6q 4008 15 2016 2016 CD cord-006870-f5w6fw6q 4008 16 . . . cord-006870-f5w6fw6q 4009 1 The the DT cord-006870-f5w6fw6q 4009 2 overall overall JJ cord-006870-f5w6fw6q 4009 3 complication complication NN cord-006870-f5w6fw6q 4009 4 rate rate NN cord-006870-f5w6fw6q 4009 5 declined decline VBD cord-006870-f5w6fw6q 4009 6 significantly significantly RB cord-006870-f5w6fw6q 4009 7 from from IN cord-006870-f5w6fw6q 4009 8 3.94 3.94 CD cord-006870-f5w6fw6q 4009 9 to to IN cord-006870-f5w6fw6q 4009 10 2.33 2.33 CD cord-006870-f5w6fw6q 4009 11 per per IN cord-006870-f5w6fw6q 4009 12 1,000 1,000 CD cord-006870-f5w6fw6q 4009 13 patient patient JJ cord-006870-f5w6fw6q 4009 14 days day NNS cord-006870-f5w6fw6q 4009 15 ( ( -LRB- cord-006870-f5w6fw6q 4009 16 p=0.031 p=0.031 NNP cord-006870-f5w6fw6q 4009 17 ) ) -RRB- cord-006870-f5w6fw6q 4009 18 . . . cord-006870-f5w6fw6q 4010 1 The the DT cord-006870-f5w6fw6q 4010 2 highest high JJS cord-006870-f5w6fw6q 4010 3 complication complication NN cord-006870-f5w6fw6q 4010 4 rate rate NN cord-006870-f5w6fw6q 4010 5 in in IN cord-006870-f5w6fw6q 4010 6 2014 2014 CD cord-006870-f5w6fw6q 4010 7 and and CC cord-006870-f5w6fw6q 4010 8 2016 2016 CD cord-006870-f5w6fw6q 4010 9 was be VBD cord-006870-f5w6fw6q 4010 10 pneumonia pneumonia NN cord-006870-f5w6fw6q 4010 11 ( ( -LRB- cord-006870-f5w6fw6q 4010 12 1.45 1.45 CD cord-006870-f5w6fw6q 4010 13 and and CC cord-006870-f5w6fw6q 4010 14 0.85 0.85 CD cord-006870-f5w6fw6q 4010 15 per per IN cord-006870-f5w6fw6q 4010 16 1,000 1,000 CD cord-006870-f5w6fw6q 4010 17 patient patient JJ cord-006870-f5w6fw6q 4010 18 days day NNS cord-006870-f5w6fw6q 4010 19 , , , cord-006870-f5w6fw6q 4010 20 respectively respectively RB cord-006870-f5w6fw6q 4010 21 ) ) -RRB- cord-006870-f5w6fw6q 4010 22 . . . cord-006870-f5w6fw6q 4011 1 The the DT cord-006870-f5w6fw6q 4011 2 proportion proportion NN cord-006870-f5w6fw6q 4011 3 of of IN cord-006870-f5w6fw6q 4011 4 patients patient NNS cord-006870-f5w6fw6q 4011 5 who who WP cord-006870-f5w6fw6q 4011 6 expired expire VBD cord-006870-f5w6fw6q 4011 7 decreased decrease VBD cord-006870-f5w6fw6q 4011 8 from from IN cord-006870-f5w6fw6q 4011 9 11.6 11.6 CD cord-006870-f5w6fw6q 4011 10 % % NN cord-006870-f5w6fw6q 4011 11 ( ( -LRB- cord-006870-f5w6fw6q 4011 12 n=51 n=51 NNP cord-006870-f5w6fw6q 4011 13 ) ) -RRB- cord-006870-f5w6fw6q 4011 14 in in IN cord-006870-f5w6fw6q 4011 15 2014 2014 CD cord-006870-f5w6fw6q 4011 16 to to IN cord-006870-f5w6fw6q 4011 17 10.5 10.5 CD cord-006870-f5w6fw6q 4011 18 % % NN cord-006870-f5w6fw6q 4011 19 ( ( -LRB- cord-006870-f5w6fw6q 4011 20 n=54 n=54 JJ cord-006870-f5w6fw6q 4011 21 ) ) -RRB- cord-006870-f5w6fw6q 4011 22 in in IN cord-006870-f5w6fw6q 4011 23 2016 2016 CD cord-006870-f5w6fw6q 4011 24 , , , cord-006870-f5w6fw6q 4011 25 though though IN cord-006870-f5w6fw6q 4011 26 not not RB cord-006870-f5w6fw6q 4011 27 significantly significantly RB cord-006870-f5w6fw6q 4011 28 ( ( -LRB- cord-006870-f5w6fw6q 4011 29 p=0.65 p=0.65 NNP cord-006870-f5w6fw6q 4011 30 ) ) -RRB- cord-006870-f5w6fw6q 4011 31 . . . cord-006870-f5w6fw6q 4012 1 There there EX cord-006870-f5w6fw6q 4012 2 were be VBD cord-006870-f5w6fw6q 4012 3 no no DT cord-006870-f5w6fw6q 4012 4 significant significant JJ cord-006870-f5w6fw6q 4012 5 differences difference NNS cord-006870-f5w6fw6q 4012 6 in in IN cord-006870-f5w6fw6q 4012 7 LOS LOS NNP cord-006870-f5w6fw6q 4012 8 among among IN cord-006870-f5w6fw6q 4012 9 patients patient NNS cord-006870-f5w6fw6q 4012 10 with with IN cord-006870-f5w6fw6q 4012 11 ISC ISC NNP cord-006870-f5w6fw6q 4012 12 , , , cord-006870-f5w6fw6q 4012 13 brain brain NN cord-006870-f5w6fw6q 4012 14 tumor tumor NN cord-006870-f5w6fw6q 4012 15 or or CC cord-006870-f5w6fw6q 4012 16 seizure seizure NN cord-006870-f5w6fw6q 4012 17 . . . cord-006870-f5w6fw6q 4013 1 However however RB cord-006870-f5w6fw6q 4013 2 , , , cord-006870-f5w6fw6q 4013 3 those those DT cord-006870-f5w6fw6q 4013 4 with with IN cord-006870-f5w6fw6q 4013 5 SAH SAH NNP cord-006870-f5w6fw6q 4013 6 or or CC cord-006870-f5w6fw6q 4013 7 ICH ICH NNP cord-006870-f5w6fw6q 4013 8 had have VBD cord-006870-f5w6fw6q 4013 9 significantly significantly RB cord-006870-f5w6fw6q 4013 10 shorter short JJR cord-006870-f5w6fw6q 4013 11 stays stay NNS cord-006870-f5w6fw6q 4013 12 in in IN cord-006870-f5w6fw6q 4013 13 2014 2014 CD cord-006870-f5w6fw6q 4014 1 ( ( -LRB- cord-006870-f5w6fw6q 4014 2 median median JJ cord-006870-f5w6fw6q 4014 3 [ [ -LRB- cord-006870-f5w6fw6q 4014 4 interquartile interquartile JJ cord-006870-f5w6fw6q 4014 5 range range NN cord-006870-f5w6fw6q 4014 6 ] ] -RRB- cord-006870-f5w6fw6q 4014 7 = = NFP cord-006870-f5w6fw6q 4015 1 3.0 3.0 CD cord-006870-f5w6fw6q 4015 2 [ [ -LRB- cord-006870-f5w6fw6q 4015 3 2.0 2.0 CD cord-006870-f5w6fw6q 4015 4 , , , cord-006870-f5w6fw6q 4015 5 9.5 9.5 CD cord-006870-f5w6fw6q 4015 6 ] ] -RRB- cord-006870-f5w6fw6q 4015 7 ) ) -RRB- cord-006870-f5w6fw6q 4016 1 versus versus IN cord-006870-f5w6fw6q 4016 2 2016 2016 CD cord-006870-f5w6fw6q 4016 3 ( ( -LRB- cord-006870-f5w6fw6q 4016 4 7.0 7.0 CD cord-006870-f5w6fw6q 4016 5 [ [ -LRB- cord-006870-f5w6fw6q 4016 6 2.0 2.0 CD cord-006870-f5w6fw6q 4016 7 , , , cord-006870-f5w6fw6q 4016 8 14.0 14.0 CD cord-006870-f5w6fw6q 4016 9 ] ] -RRB- cord-006870-f5w6fw6q 4016 10 ) ) -RRB- cord-006870-f5w6fw6q 4017 1 ( ( -LRB- cord-006870-f5w6fw6q 4017 2 p=0.032 p=0.032 NNP cord-006870-f5w6fw6q 4017 3 ) ) -RRB- cord-006870-f5w6fw6q 4017 4 . . . cord-006870-f5w6fw6q 4018 1 Data datum NNS cord-006870-f5w6fw6q 4018 2 suggest suggest VBP cord-006870-f5w6fw6q 4018 3 that that IN cord-006870-f5w6fw6q 4018 4 over over IN cord-006870-f5w6fw6q 4018 5 the the DT cord-006870-f5w6fw6q 4018 6 initial initial JJ cord-006870-f5w6fw6q 4018 7 3-year 3-year CD cord-006870-f5w6fw6q 4018 8 period period NN cord-006870-f5w6fw6q 4018 9 , , , cord-006870-f5w6fw6q 4018 10 complication complication NN cord-006870-f5w6fw6q 4018 11 rates rate NNS cord-006870-f5w6fw6q 4018 12 among among IN cord-006870-f5w6fw6q 4018 13 patients patient NNS cord-006870-f5w6fw6q 4018 14 in in IN cord-006870-f5w6fw6q 4018 15 the the DT cord-006870-f5w6fw6q 4018 16 NCCU NCCU NNP cord-006870-f5w6fw6q 4018 17 improved improve VBD cord-006870-f5w6fw6q 4018 18 . . . cord-006870-f5w6fw6q 4019 1 LOS LOS NNP cord-006870-f5w6fw6q 4019 2 did do VBD cord-006870-f5w6fw6q 4019 3 increase increase VB cord-006870-f5w6fw6q 4019 4 for for IN cord-006870-f5w6fw6q 4019 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4019 6 patients patient NNS cord-006870-f5w6fw6q 4019 7 ; ; : cord-006870-f5w6fw6q 4019 8 however however RB cord-006870-f5w6fw6q 4019 9 , , , cord-006870-f5w6fw6q 4019 10 this this DT cord-006870-f5w6fw6q 4019 11 may may MD cord-006870-f5w6fw6q 4019 12 be be VB cord-006870-f5w6fw6q 4019 13 related relate VBN cord-006870-f5w6fw6q 4019 14 to to IN cord-006870-f5w6fw6q 4019 15 greater great JJR cord-006870-f5w6fw6q 4019 16 severity severity NN cord-006870-f5w6fw6q 4019 17 of of IN cord-006870-f5w6fw6q 4019 18 illness illness NN cord-006870-f5w6fw6q 4019 19 in in IN cord-006870-f5w6fw6q 4019 20 the the DT cord-006870-f5w6fw6q 4019 21 patient patient JJ cord-006870-f5w6fw6q 4019 22 population population NN cord-006870-f5w6fw6q 4019 23 over over IN cord-006870-f5w6fw6q 4019 24 time time NN cord-006870-f5w6fw6q 4019 25 . . . cord-006870-f5w6fw6q 4020 1 Further further JJ cord-006870-f5w6fw6q 4020 2 analyses analysis NNS cord-006870-f5w6fw6q 4020 3 will will MD cord-006870-f5w6fw6q 4020 4 be be VB cord-006870-f5w6fw6q 4020 5 conducted conduct VBN cord-006870-f5w6fw6q 4020 6 to to TO cord-006870-f5w6fw6q 4020 7 account account VB cord-006870-f5w6fw6q 4020 8 for for IN cord-006870-f5w6fw6q 4020 9 severity severity NN cord-006870-f5w6fw6q 4020 10 and and CC cord-006870-f5w6fw6q 4020 11 other other JJ cord-006870-f5w6fw6q 4020 12 factors factor NNS cord-006870-f5w6fw6q 4020 13 . . . cord-006870-f5w6fw6q 4021 1 Delirium delirium NN cord-006870-f5w6fw6q 4021 2 is be VBZ cord-006870-f5w6fw6q 4021 3 a a DT cord-006870-f5w6fw6q 4021 4 frequently frequently RB cord-006870-f5w6fw6q 4021 5 seen see VBN cord-006870-f5w6fw6q 4021 6 but but CC cord-006870-f5w6fw6q 4021 7 underestimated underestimated JJ cord-006870-f5w6fw6q 4021 8 problem problem NN cord-006870-f5w6fw6q 4021 9 in in IN cord-006870-f5w6fw6q 4021 10 critical critical JJ cord-006870-f5w6fw6q 4021 11 care care NN cord-006870-f5w6fw6q 4021 12 settings setting NNS cord-006870-f5w6fw6q 4021 13 . . . cord-006870-f5w6fw6q 4022 1 Delirium delirium NN cord-006870-f5w6fw6q 4022 2 screening screening NN cord-006870-f5w6fw6q 4022 3 is be VBZ cord-006870-f5w6fw6q 4022 4 considered consider VBN cord-006870-f5w6fw6q 4022 5 time time NN cord-006870-f5w6fw6q 4022 6 consuming consume VBG cord-006870-f5w6fw6q 4022 7 , , , cord-006870-f5w6fw6q 4022 8 which which WDT cord-006870-f5w6fw6q 4022 9 is be VBZ cord-006870-f5w6fw6q 4022 10 one one CD cord-006870-f5w6fw6q 4022 11 of of IN cord-006870-f5w6fw6q 4022 12 the the DT cord-006870-f5w6fw6q 4022 13 factors factor NNS cord-006870-f5w6fw6q 4022 14 leading lead VBG cord-006870-f5w6fw6q 4022 15 to to IN cord-006870-f5w6fw6q 4022 16 under under IN cord-006870-f5w6fw6q 4022 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 4022 18 . . . cord-006870-f5w6fw6q 4023 1 The the DT cord-006870-f5w6fw6q 4023 2 CAM CAM NNP cord-006870-f5w6fw6q 4023 3 - - HYPH cord-006870-f5w6fw6q 4023 4 ICU ICU NNP cord-006870-f5w6fw6q 4023 5 screening screening NN cord-006870-f5w6fw6q 4023 6 tool tool NN cord-006870-f5w6fw6q 4023 7 for for IN cord-006870-f5w6fw6q 4023 8 delirium delirium NN cord-006870-f5w6fw6q 4023 9 has have VBZ cord-006870-f5w6fw6q 4023 10 been be VBN cord-006870-f5w6fw6q 4023 11 validated validate VBN cord-006870-f5w6fw6q 4023 12 in in IN cord-006870-f5w6fw6q 4023 13 medical medical JJ cord-006870-f5w6fw6q 4023 14 and and CC cord-006870-f5w6fw6q 4023 15 surgical surgical JJ cord-006870-f5w6fw6q 4023 16 ICUs icus NN cord-006870-f5w6fw6q 4023 17 . . . cord-006870-f5w6fw6q 4024 1 Among among IN cord-006870-f5w6fw6q 4024 2 neurological neurological JJ cord-006870-f5w6fw6q 4024 3 patients patient NNS cord-006870-f5w6fw6q 4024 4 , , , cord-006870-f5w6fw6q 4024 5 it -PRON- PRP cord-006870-f5w6fw6q 4024 6 has have VBZ cord-006870-f5w6fw6q 4024 7 been be VBN cord-006870-f5w6fw6q 4024 8 validated validate VBN cord-006870-f5w6fw6q 4024 9 in in IN cord-006870-f5w6fw6q 4024 10 stroke stroke NN cord-006870-f5w6fw6q 4024 11 patients patient NNS cord-006870-f5w6fw6q 4024 12 but but CC cord-006870-f5w6fw6q 4024 13 not not RB cord-006870-f5w6fw6q 4024 14 in in IN cord-006870-f5w6fw6q 4024 15 general general JJ cord-006870-f5w6fw6q 4024 16 neurocritical neurocritical NNP cord-006870-f5w6fw6q 4024 17 care care NN cord-006870-f5w6fw6q 4024 18 population population NN cord-006870-f5w6fw6q 4024 19 . . . cord-006870-f5w6fw6q 4025 1 This this DT cord-006870-f5w6fw6q 4025 2 study study NN cord-006870-f5w6fw6q 4025 3 was be VBD cord-006870-f5w6fw6q 4025 4 designed design VBN cord-006870-f5w6fw6q 4025 5 to to TO cord-006870-f5w6fw6q 4025 6 validate validate VB cord-006870-f5w6fw6q 4025 7 CAM CAM NNP cord-006870-f5w6fw6q 4025 8 - - HYPH cord-006870-f5w6fw6q 4025 9 ICU ICU NNP cord-006870-f5w6fw6q 4025 10 flow flow NN cord-006870-f5w6fw6q 4025 11 sheet sheet NN cord-006870-f5w6fw6q 4025 12 in in IN cord-006870-f5w6fw6q 4025 13 neurointensive neurointensive NNP cord-006870-f5w6fw6q 4025 14 care care NN cord-006870-f5w6fw6q 4025 15 unit unit NN cord-006870-f5w6fw6q 4025 16 . . . cord-006870-f5w6fw6q 4026 1 A a DT cord-006870-f5w6fw6q 4026 2 prospective prospective JJ cord-006870-f5w6fw6q 4026 3 cohort cohort NN cord-006870-f5w6fw6q 4026 4 study study NN cord-006870-f5w6fw6q 4026 5 was be VBD cord-006870-f5w6fw6q 4026 6 conducted conduct VBN cord-006870-f5w6fw6q 4026 7 in in IN cord-006870-f5w6fw6q 4026 8 a a DT cord-006870-f5w6fw6q 4026 9 16 16 CD cord-006870-f5w6fw6q 4026 10 bed bed NN cord-006870-f5w6fw6q 4026 11 neurointensive neurointensive NNP cord-006870-f5w6fw6q 4026 12 care care NN cord-006870-f5w6fw6q 4026 13 unit unit NN cord-006870-f5w6fw6q 4026 14 of of IN cord-006870-f5w6fw6q 4026 15 a a DT cord-006870-f5w6fw6q 4026 16 university university NN cord-006870-f5w6fw6q 4026 17 hospital hospital NN cord-006870-f5w6fw6q 4026 18 . . . cord-006870-f5w6fw6q 4027 1 Patients patient NNS cord-006870-f5w6fw6q 4027 2 meeting meet VBG cord-006870-f5w6fw6q 4027 3 the the DT cord-006870-f5w6fw6q 4027 4 inclusion inclusion NN cord-006870-f5w6fw6q 4027 5 criteria criterion NNS cord-006870-f5w6fw6q 4027 6 ( ( -LRB- cord-006870-f5w6fw6q 4027 7 all all DT cord-006870-f5w6fw6q 4027 8 NICU NICU NNP cord-006870-f5w6fw6q 4027 9 patients patient NNS cord-006870-f5w6fw6q 4027 10 ) ) -RRB- cord-006870-f5w6fw6q 4027 11 and and CC cord-006870-f5w6fw6q 4027 12 exclusion exclusion NN cord-006870-f5w6fw6q 4027 13 criteria criterion NNS cord-006870-f5w6fw6q 4027 14 ( ( -LRB- cord-006870-f5w6fw6q 4027 15 comatosed comatosed JJ cord-006870-f5w6fw6q 4027 16 , , , cord-006870-f5w6fw6q 4027 17 aphasic aphasic JJ cord-006870-f5w6fw6q 4027 18 , , , cord-006870-f5w6fw6q 4027 19 psychotic psychotic JJ cord-006870-f5w6fw6q 4027 20 , , , cord-006870-f5w6fw6q 4027 21 prior prior JJ cord-006870-f5w6fw6q 4027 22 diagnosis diagnosis NN cord-006870-f5w6fw6q 4027 23 of of IN cord-006870-f5w6fw6q 4027 24 neurocognitive neurocognitive JJ cord-006870-f5w6fw6q 4027 25 disease disease NN cord-006870-f5w6fw6q 4027 26 , , , cord-006870-f5w6fw6q 4027 27 persistently persistently RB cord-006870-f5w6fw6q 4027 28 vegetative vegetative JJ cord-006870-f5w6fw6q 4027 29 state state NN cord-006870-f5w6fw6q 4027 30 , , , cord-006870-f5w6fw6q 4027 31 sedated sedate VBN cord-006870-f5w6fw6q 4027 32 ) ) -RRB- cord-006870-f5w6fw6q 4028 1 were be VBD cord-006870-f5w6fw6q 4028 2 screened screen VBN cord-006870-f5w6fw6q 4028 3 for for IN cord-006870-f5w6fw6q 4028 4 delirium delirium NN cord-006870-f5w6fw6q 4028 5 by by IN cord-006870-f5w6fw6q 4028 6 ( ( -LRB- cord-006870-f5w6fw6q 4028 7 1 1 CD cord-006870-f5w6fw6q 4028 8 ) ) -RRB- cord-006870-f5w6fw6q 4028 9 a a DT cord-006870-f5w6fw6q 4028 10 nurse nurse NN cord-006870-f5w6fw6q 4028 11 practitioner practitioner NN cord-006870-f5w6fw6q 4028 12 using use VBG cord-006870-f5w6fw6q 4028 13 confusion confusion NN cord-006870-f5w6fw6q 4028 14 assessment assessment NN cord-006870-f5w6fw6q 4028 15 method method NN cord-006870-f5w6fw6q 4028 16 ( ( -LRB- cord-006870-f5w6fw6q 4028 17 CAM CAM NNP cord-006870-f5w6fw6q 4028 18 - - HYPH cord-006870-f5w6fw6q 4028 19 ICU ICU NNP cord-006870-f5w6fw6q 4028 20 ) ) -RRB- cord-006870-f5w6fw6q 4028 21 and and CC cord-006870-f5w6fw6q 4028 22 ( ( -LRB- cord-006870-f5w6fw6q 4028 23 2 2 LS cord-006870-f5w6fw6q 4028 24 ) ) -RRB- cord-006870-f5w6fw6q 4028 25 a a DT cord-006870-f5w6fw6q 4028 26 physician physician NN cord-006870-f5w6fw6q 4028 27 reference reference NN cord-006870-f5w6fw6q 4028 28 rator rator NN cord-006870-f5w6fw6q 4028 29 using use VBG cord-006870-f5w6fw6q 4028 30 delirium delirium NN cord-006870-f5w6fw6q 4028 31 screening screen VBG cord-006870-f5w6fw6q 4028 32 criteria criterion NNS cord-006870-f5w6fw6q 4028 33 in in IN cord-006870-f5w6fw6q 4028 34 Diagnostic Diagnostic NNP cord-006870-f5w6fw6q 4028 35 and and CC cord-006870-f5w6fw6q 4028 36 Statistical Statistical NNP cord-006870-f5w6fw6q 4028 37 Manual Manual NNP cord-006870-f5w6fw6q 4028 38 of of IN cord-006870-f5w6fw6q 4028 39 Mental Mental NNP cord-006870-f5w6fw6q 4028 40 Disorders-5 Disorders-5 NNP cord-006870-f5w6fw6q 4028 41 . . . cord-006870-f5w6fw6q 4029 1 Assessments assessment NNS cord-006870-f5w6fw6q 4029 2 were be VBD cord-006870-f5w6fw6q 4029 3 done do VBN cord-006870-f5w6fw6q 4029 4 daily daily JJ cord-006870-f5w6fw6q 4029 5 Monday Monday NNP cord-006870-f5w6fw6q 4029 6 through through IN cord-006870-f5w6fw6q 4029 7 Friday Friday NNP cord-006870-f5w6fw6q 4029 8 for for IN cord-006870-f5w6fw6q 4029 9 the the DT cord-006870-f5w6fw6q 4029 10 ICU ICU NNP cord-006870-f5w6fw6q 4029 11 stay stay NN cord-006870-f5w6fw6q 4029 12 . . . cord-006870-f5w6fw6q 4030 1 Paired paired JJ cord-006870-f5w6fw6q 4030 2 assessments assessment NNS cord-006870-f5w6fw6q 4030 3 were be VBD cord-006870-f5w6fw6q 4030 4 done do VBN cord-006870-f5w6fw6q 4030 5 less less JJR cord-006870-f5w6fw6q 4030 6 than than IN cord-006870-f5w6fw6q 4030 7 4 4 CD cord-006870-f5w6fw6q 4030 8 hours hour NNS cord-006870-f5w6fw6q 4030 9 apart apart RB cord-006870-f5w6fw6q 4030 10 . . . cord-006870-f5w6fw6q 4031 1 The the DT cord-006870-f5w6fw6q 4031 2 study study NN cord-006870-f5w6fw6q 4031 3 enrolled enrol VBD cord-006870-f5w6fw6q 4031 4 50 50 CD cord-006870-f5w6fw6q 4031 5 patients patient NNS cord-006870-f5w6fw6q 4031 6 ( ( -LRB- cord-006870-f5w6fw6q 4031 7 19 19 CD cord-006870-f5w6fw6q 4031 8 male male NN cord-006870-f5w6fw6q 4031 9 , , , cord-006870-f5w6fw6q 4031 10 31 31 CD cord-006870-f5w6fw6q 4031 11 female female NN cord-006870-f5w6fw6q 4031 12 ) ) -RRB- cord-006870-f5w6fw6q 4031 13 . . . cord-006870-f5w6fw6q 4032 1 159 159 CD cord-006870-f5w6fw6q 4032 2 daily daily JJ cord-006870-f5w6fw6q 4032 3 assessments assessment NNS cord-006870-f5w6fw6q 4032 4 were be VBD cord-006870-f5w6fw6q 4032 5 done do VBN cord-006870-f5w6fw6q 4032 6 . . . cord-006870-f5w6fw6q 4033 1 Mean mean JJ cord-006870-f5w6fw6q 4033 2 age age NN cord-006870-f5w6fw6q 4033 3 of of IN cord-006870-f5w6fw6q 4033 4 the the DT cord-006870-f5w6fw6q 4033 5 patients patient NNS cord-006870-f5w6fw6q 4033 6 was be VBD cord-006870-f5w6fw6q 4033 7 63.5 63.5 CD cord-006870-f5w6fw6q 4033 8 and and CC cord-006870-f5w6fw6q 4033 9 mean mean VB cord-006870-f5w6fw6q 4033 10 SAP SAP NNP cord-006870-f5w6fw6q 4033 11 score score NN cord-006870-f5w6fw6q 4033 12 was be VBD cord-006870-f5w6fw6q 4033 13 23 23 CD cord-006870-f5w6fw6q 4033 14 . . . cord-006870-f5w6fw6q 4034 1 Admitting admit VBG cord-006870-f5w6fw6q 4034 2 diagnoses diagnosis NNS cord-006870-f5w6fw6q 4034 3 were be VBD cord-006870-f5w6fw6q 4034 4 ICH ICH NNP cord-006870-f5w6fw6q 4034 5 ( ( -LRB- cord-006870-f5w6fw6q 4034 6 8) 8) NNP cord-006870-f5w6fw6q 4034 7 , , , cord-006870-f5w6fw6q 4034 8 SAH SAH NNP cord-006870-f5w6fw6q 4034 9 ( ( -LRB- cord-006870-f5w6fw6q 4034 10 10 10 CD cord-006870-f5w6fw6q 4034 11 ) ) -RRB- cord-006870-f5w6fw6q 4034 12 , , , cord-006870-f5w6fw6q 4034 13 ischemic ischemic JJ cord-006870-f5w6fw6q 4034 14 stroke stroke NN cord-006870-f5w6fw6q 4034 15 ( ( -LRB- cord-006870-f5w6fw6q 4034 16 5 5 CD cord-006870-f5w6fw6q 4034 17 ) ) -RRB- cord-006870-f5w6fw6q 4034 18 , , , cord-006870-f5w6fw6q 4034 19 tumor tumor NN cord-006870-f5w6fw6q 4034 20 ( ( -LRB- cord-006870-f5w6fw6q 4034 21 9 9 CD cord-006870-f5w6fw6q 4034 22 ) ) -RRB- cord-006870-f5w6fw6q 4034 23 , , , cord-006870-f5w6fw6q 4034 24 spinal spinal NNP cord-006870-f5w6fw6q 4034 25 surgery(4 surgery(4 NNP cord-006870-f5w6fw6q 4034 26 ) ) -RRB- cord-006870-f5w6fw6q 4034 27 , , , cord-006870-f5w6fw6q 4034 28 neurological neurological NNP cord-006870-f5w6fw6q 4034 29 infections(4 infections(4 NNP cord-006870-f5w6fw6q 4034 30 ) ) -RRB- cord-006870-f5w6fw6q 4034 31 , , , cord-006870-f5w6fw6q 4034 32 seizures(3),elective seizures(3),elective JJ cord-006870-f5w6fw6q 4034 33 angiograms(4 angiograms(4 NN cord-006870-f5w6fw6q 4034 34 ) ) -RRB- cord-006870-f5w6fw6q 4034 35 , , , cord-006870-f5w6fw6q 4034 36 hydrocephalus(1 hydrocephalus(1 ADD cord-006870-f5w6fw6q 4034 37 ) ) -RRB- cord-006870-f5w6fw6q 4034 38 , , , cord-006870-f5w6fw6q 4034 39 transverse transverse JJ cord-006870-f5w6fw6q 4034 40 myelitis(1 myelitis(1 CD cord-006870-f5w6fw6q 4034 41 ) ) -RRB- cord-006870-f5w6fw6q 4034 42 and and CC cord-006870-f5w6fw6q 4034 43 AV AV NNP cord-006870-f5w6fw6q 4034 44 dural dural NN cord-006870-f5w6fw6q 4034 45 fistula(1 fistula(1 NN cord-006870-f5w6fw6q 4034 46 ) ) -RRB- cord-006870-f5w6fw6q 4034 47 . . . cord-006870-f5w6fw6q 4035 1 Using use VBG cord-006870-f5w6fw6q 4035 2 DSM-5 DSM-5 NNP cord-006870-f5w6fw6q 4035 3 criteria criterion NNS cord-006870-f5w6fw6q 4035 4 , , , cord-006870-f5w6fw6q 4035 5 the the DT cord-006870-f5w6fw6q 4035 6 reference reference NN cord-006870-f5w6fw6q 4035 7 rator rator NN cord-006870-f5w6fw6q 4035 8 identified identify VBD cord-006870-f5w6fw6q 4035 9 delirium delirium NN cord-006870-f5w6fw6q 4035 10 in in IN cord-006870-f5w6fw6q 4035 11 8 8 CD cord-006870-f5w6fw6q 4035 12 out out IN cord-006870-f5w6fw6q 4035 13 of of IN cord-006870-f5w6fw6q 4035 14 50 50 CD cord-006870-f5w6fw6q 4035 15 ( ( -LRB- cord-006870-f5w6fw6q 4035 16 16 16 CD cord-006870-f5w6fw6q 4035 17 % % NN cord-006870-f5w6fw6q 4035 18 ) ) -RRB- cord-006870-f5w6fw6q 4035 19 patients patient NNS cord-006870-f5w6fw6q 4035 20 during during IN cord-006870-f5w6fw6q 4035 21 the the DT cord-006870-f5w6fw6q 4035 22 ICU ICU NNP cord-006870-f5w6fw6q 4035 23 stay stay NN cord-006870-f5w6fw6q 4035 24 . . . cord-006870-f5w6fw6q 4036 1 27 27 CD cord-006870-f5w6fw6q 4036 2 out out IN cord-006870-f5w6fw6q 4036 3 of of IN cord-006870-f5w6fw6q 4036 4 159 159 CD cord-006870-f5w6fw6q 4036 5 assessments assessment NNS cord-006870-f5w6fw6q 4036 6 were be VBD cord-006870-f5w6fw6q 4036 7 positive positive JJ cord-006870-f5w6fw6q 4036 8 for for IN cord-006870-f5w6fw6q 4036 9 delirium delirium NN cord-006870-f5w6fw6q 4036 10 according accord VBG cord-006870-f5w6fw6q 4036 11 to to IN cord-006870-f5w6fw6q 4036 12 DSM-5 DSM-5 NNP cord-006870-f5w6fw6q 4036 13 and and CC cord-006870-f5w6fw6q 4036 14 29 29 CD cord-006870-f5w6fw6q 4036 15 according accord VBG cord-006870-f5w6fw6q 4036 16 to to IN cord-006870-f5w6fw6q 4036 17 CAM CAM NNP cord-006870-f5w6fw6q 4036 18 - - HYPH cord-006870-f5w6fw6q 4036 19 ICU ICU NNP cord-006870-f5w6fw6q 4036 20 . . . cord-006870-f5w6fw6q 4037 1 CAM CAM NNP cord-006870-f5w6fw6q 4037 2 - - HYPH cord-006870-f5w6fw6q 4037 3 ICU ICU NNP cord-006870-f5w6fw6q 4037 4 flow flow NN cord-006870-f5w6fw6q 4037 5 sheet sheet NN cord-006870-f5w6fw6q 4037 6 had have VBD cord-006870-f5w6fw6q 4037 7 sensitivity sensitivity NN cord-006870-f5w6fw6q 4037 8 of of IN cord-006870-f5w6fw6q 4037 9 96.43 96.43 CD cord-006870-f5w6fw6q 4037 10 % % NN cord-006870-f5w6fw6q 4037 11 ( ( -LRB- cord-006870-f5w6fw6q 4037 12 95%CI 95%ci CD cord-006870-f5w6fw6q 4037 13 81.65 81.65 CD cord-006870-f5w6fw6q 4037 14 % % NN cord-006870-f5w6fw6q 4037 15 -99.91 -99.91 JJ cord-006870-f5w6fw6q 4037 16 % % NN cord-006870-f5w6fw6q 4037 17 ) ) -RRB- cord-006870-f5w6fw6q 4037 18 and and CC cord-006870-f5w6fw6q 4037 19 specificity specificity NN cord-006870-f5w6fw6q 4037 20 of of IN cord-006870-f5w6fw6q 4037 21 98.51 98.51 CD cord-006870-f5w6fw6q 4037 22 % % NN cord-006870-f5w6fw6q 4037 23 ( ( -LRB- cord-006870-f5w6fw6q 4037 24 95%CI 95%ci CD cord-006870-f5w6fw6q 4037 25 94.71%-99.82 94.71%-99.82 CD cord-006870-f5w6fw6q 4037 26 % % NN cord-006870-f5w6fw6q 4037 27 ) ) -RRB- cord-006870-f5w6fw6q 4037 28 . . . cord-006870-f5w6fw6q 4038 1 CAM CAM NNP cord-006870-f5w6fw6q 4038 2 - - HYPH cord-006870-f5w6fw6q 4038 3 ICU ICU NNP cord-006870-f5w6fw6q 4038 4 has have VBZ cord-006870-f5w6fw6q 4038 5 high high JJ cord-006870-f5w6fw6q 4038 6 sensitivity sensitivity NN cord-006870-f5w6fw6q 4038 7 and and CC cord-006870-f5w6fw6q 4038 8 specificity specificity NN cord-006870-f5w6fw6q 4038 9 for for IN cord-006870-f5w6fw6q 4038 10 diagnosing diagnose VBG cord-006870-f5w6fw6q 4038 11 delirium delirium NN cord-006870-f5w6fw6q 4038 12 in in IN cord-006870-f5w6fw6q 4038 13 critically critically RB cord-006870-f5w6fw6q 4038 14 ill ill JJ cord-006870-f5w6fw6q 4038 15 neurological neurological JJ cord-006870-f5w6fw6q 4038 16 population population NN cord-006870-f5w6fw6q 4038 17 . . . cord-006870-f5w6fw6q 4039 1 It -PRON- PRP cord-006870-f5w6fw6q 4039 2 is be VBZ cord-006870-f5w6fw6q 4039 3 a a DT cord-006870-f5w6fw6q 4039 4 valid valid JJ cord-006870-f5w6fw6q 4039 5 tool tool NN cord-006870-f5w6fw6q 4039 6 for for IN cord-006870-f5w6fw6q 4039 7 diagnosing diagnose VBG cord-006870-f5w6fw6q 4039 8 delirium delirium NN cord-006870-f5w6fw6q 4039 9 . . . cord-006870-f5w6fw6q 4040 1 A a DT cord-006870-f5w6fw6q 4040 2 value value NN cord-006870-f5w6fw6q 4040 3 stream stream NN cord-006870-f5w6fw6q 4040 4 mapping mapping NN cord-006870-f5w6fw6q 4040 5 event event NN cord-006870-f5w6fw6q 4040 6 ( ( -LRB- cord-006870-f5w6fw6q 4040 7 VSM VSM NNP cord-006870-f5w6fw6q 4040 8 ) ) -RRB- cord-006870-f5w6fw6q 4040 9 for for IN cord-006870-f5w6fw6q 4040 10 general general NNP cord-006870-f5w6fw6q 4040 11 neurology neurology NNP cord-006870-f5w6fw6q 4040 12 inpatients inpatient NNS cord-006870-f5w6fw6q 4040 13 , , , cord-006870-f5w6fw6q 4040 14 revealed reveal VBD cord-006870-f5w6fw6q 4040 15 multiple multiple JJ cord-006870-f5w6fw6q 4040 16 barriers barrier NNS cord-006870-f5w6fw6q 4040 17 related relate VBN cord-006870-f5w6fw6q 4040 18 to to IN cord-006870-f5w6fw6q 4040 19 videofluoroscopy videofluoroscopy NNP cord-006870-f5w6fw6q 4040 20 swallow swallow NN cord-006870-f5w6fw6q 4040 21 studies study NNS cord-006870-f5w6fw6q 4040 22 . . . cord-006870-f5w6fw6q 4041 1 There there EX cord-006870-f5w6fw6q 4041 2 was be VBD cord-006870-f5w6fw6q 4041 3 a a DT cord-006870-f5w6fw6q 4041 4 high high JJ cord-006870-f5w6fw6q 4041 5 volume volume NN cord-006870-f5w6fw6q 4041 6 of of IN cord-006870-f5w6fw6q 4041 7 patients patient NNS cord-006870-f5w6fw6q 4041 8 requiring require VBG cord-006870-f5w6fw6q 4041 9 instrumental instrumental JJ cord-006870-f5w6fw6q 4041 10 swallow swallow NN cord-006870-f5w6fw6q 4041 11 assessments assessment NNS cord-006870-f5w6fw6q 4041 12 , , , cord-006870-f5w6fw6q 4041 13 a a DT cord-006870-f5w6fw6q 4041 14 limited limited JJ cord-006870-f5w6fw6q 4041 15 number number NN cord-006870-f5w6fw6q 4041 16 of of IN cord-006870-f5w6fw6q 4041 17 radiology radiology NN cord-006870-f5w6fw6q 4041 18 appointments appointment NNS cord-006870-f5w6fw6q 4041 19 , , , cord-006870-f5w6fw6q 4041 20 and and CC cord-006870-f5w6fw6q 4041 21 transportation transportation NN cord-006870-f5w6fw6q 4041 22 delays delay NNS cord-006870-f5w6fw6q 4041 23 that that WDT cord-006870-f5w6fw6q 4041 24 were be VBD cord-006870-f5w6fw6q 4041 25 delaying delay VBG cord-006870-f5w6fw6q 4041 26 feeding feeding NN cord-006870-f5w6fw6q 4041 27 plans plan NNS cord-006870-f5w6fw6q 4041 28 , , , cord-006870-f5w6fw6q 4041 29 discharge discharge NN cord-006870-f5w6fw6q 4041 30 recommendations recommendation NNS cord-006870-f5w6fw6q 4041 31 and and CC cord-006870-f5w6fw6q 4041 32 goals goal NNS cord-006870-f5w6fw6q 4041 33 of of IN cord-006870-f5w6fw6q 4041 34 care care NN cord-006870-f5w6fw6q 4041 35 discussions discussion NNS cord-006870-f5w6fw6q 4041 36 . . . cord-006870-f5w6fw6q 4042 1 An an DT cord-006870-f5w6fw6q 4042 2 Operations Operations NNPS cord-006870-f5w6fw6q 4042 3 Engineer Engineer NNP cord-006870-f5w6fw6q 4042 4 involved involve VBN cord-006870-f5w6fw6q 4042 5 in in IN cord-006870-f5w6fw6q 4042 6 the the DT cord-006870-f5w6fw6q 4042 7 VSM VSM NNP cord-006870-f5w6fw6q 4042 8 event event NN cord-006870-f5w6fw6q 4042 9 started start VBD cord-006870-f5w6fw6q 4042 10 the the DT cord-006870-f5w6fw6q 4042 11 process process NN cord-006870-f5w6fw6q 4042 12 by by IN cord-006870-f5w6fw6q 4042 13 collecting collect VBG cord-006870-f5w6fw6q 4042 14 observational observational JJ cord-006870-f5w6fw6q 4042 15 data datum NNS cord-006870-f5w6fw6q 4042 16 regariing regarie VBG cord-006870-f5w6fw6q 4042 17 timing timing NN cord-006870-f5w6fw6q 4042 18 . . . cord-006870-f5w6fw6q 4043 1 After after IN cord-006870-f5w6fw6q 4043 2 meeting meet VBG cord-006870-f5w6fw6q 4043 3 with with IN cord-006870-f5w6fw6q 4043 4 the the DT cord-006870-f5w6fw6q 4043 5 Chief Chief NNP cord-006870-f5w6fw6q 4043 6 Operating Operating NNP cord-006870-f5w6fw6q 4043 7 Officer Officer NNP cord-006870-f5w6fw6q 4043 8 , , , cord-006870-f5w6fw6q 4043 9 Director Director NNP cord-006870-f5w6fw6q 4043 10 of of IN cord-006870-f5w6fw6q 4043 11 Patient Patient NNP cord-006870-f5w6fw6q 4043 12 Transport Transport NNP cord-006870-f5w6fw6q 4043 13 , , , cord-006870-f5w6fw6q 4043 14 Director Director NNP cord-006870-f5w6fw6q 4043 15 of of IN cord-006870-f5w6fw6q 4043 16 Radiology Radiology NNP cord-006870-f5w6fw6q 4043 17 , , , cord-006870-f5w6fw6q 4043 18 Speech Speech NNP cord-006870-f5w6fw6q 4043 19 Pathology Pathology NNP cord-006870-f5w6fw6q 4043 20 Manager Manager NNP cord-006870-f5w6fw6q 4043 21 , , , cord-006870-f5w6fw6q 4043 22 Neuro Neuro NNP cord-006870-f5w6fw6q 4043 23 Intensive Intensive NNP cord-006870-f5w6fw6q 4043 24 Care Care NNP cord-006870-f5w6fw6q 4043 25 Unit Unit NNP cord-006870-f5w6fw6q 4043 26 Manager Manager NNP cord-006870-f5w6fw6q 4043 27 and and CC cord-006870-f5w6fw6q 4043 28 the the DT cord-006870-f5w6fw6q 4043 29 Operations Operations NNPS cord-006870-f5w6fw6q 4043 30 Engineer Engineer NNP cord-006870-f5w6fw6q 4043 31 , , , cord-006870-f5w6fw6q 4043 32 a a DT cord-006870-f5w6fw6q 4043 33 pilot pilot NN cord-006870-f5w6fw6q 4043 34 program program NN cord-006870-f5w6fw6q 4043 35 was be VBD cord-006870-f5w6fw6q 4043 36 agreed agree VBN cord-006870-f5w6fw6q 4043 37 upon upon IN cord-006870-f5w6fw6q 4043 38 . . . cord-006870-f5w6fw6q 4044 1 The the DT cord-006870-f5w6fw6q 4044 2 results result NNS cord-006870-f5w6fw6q 4044 3 for for IN cord-006870-f5w6fw6q 4044 4 the the DT cord-006870-f5w6fw6q 4044 5 three three CD cord-006870-f5w6fw6q 4044 6 week week NN cord-006870-f5w6fw6q 4044 7 pilot pilot NN cord-006870-f5w6fw6q 4044 8 program program NN cord-006870-f5w6fw6q 4044 9 were be VBD cord-006870-f5w6fw6q 4044 10 successful successful JJ cord-006870-f5w6fw6q 4044 11 , , , cord-006870-f5w6fw6q 4044 12 and and CC cord-006870-f5w6fw6q 4044 13 resulted result VBD cord-006870-f5w6fw6q 4044 14 in in IN cord-006870-f5w6fw6q 4044 15 a a DT cord-006870-f5w6fw6q 4044 16 permanent permanent JJ cord-006870-f5w6fw6q 4044 17 change change NN cord-006870-f5w6fw6q 4044 18 in in IN cord-006870-f5w6fw6q 4044 19 procedure procedure NN cord-006870-f5w6fw6q 4044 20 . . . cord-006870-f5w6fw6q 4045 1 The the DT cord-006870-f5w6fw6q 4045 2 pilot pilot NN cord-006870-f5w6fw6q 4045 3 data datum NNS cord-006870-f5w6fw6q 4045 4 showed show VBD cord-006870-f5w6fw6q 4045 5 a a DT cord-006870-f5w6fw6q 4045 6 decrease decrease NN cord-006870-f5w6fw6q 4045 7 in in IN cord-006870-f5w6fw6q 4045 8 test test NN cord-006870-f5w6fw6q 4045 9 time time NN cord-006870-f5w6fw6q 4045 10 by by IN cord-006870-f5w6fw6q 4045 11 5 5 CD cord-006870-f5w6fw6q 4045 12 minutes minute NNS cord-006870-f5w6fw6q 4045 13 , , , cord-006870-f5w6fw6q 4045 14 a a DT cord-006870-f5w6fw6q 4045 15 decrease decrease NN cord-006870-f5w6fw6q 4045 16 in in IN cord-006870-f5w6fw6q 4045 17 transport transport NN cord-006870-f5w6fw6q 4045 18 delays delay NNS cord-006870-f5w6fw6q 4045 19 by by IN cord-006870-f5w6fw6q 4045 20 13 13 CD cord-006870-f5w6fw6q 4045 21 minutes minute NNS cord-006870-f5w6fw6q 4045 22 , , , cord-006870-f5w6fw6q 4045 23 and and CC cord-006870-f5w6fw6q 4045 24 a a DT cord-006870-f5w6fw6q 4045 25 decrease decrease NN cord-006870-f5w6fw6q 4045 26 in in IN cord-006870-f5w6fw6q 4045 27 length length NN cord-006870-f5w6fw6q 4045 28 of of IN cord-006870-f5w6fw6q 4045 29 stay stay NN cord-006870-f5w6fw6q 4045 30 by by IN cord-006870-f5w6fw6q 4045 31 0.6 0.6 CD cord-006870-f5w6fw6q 4045 32 days day NNS cord-006870-f5w6fw6q 4045 33 . . . cord-006870-f5w6fw6q 4046 1 The the DT cord-006870-f5w6fw6q 4046 2 number number NN cord-006870-f5w6fw6q 4046 3 of of IN cord-006870-f5w6fw6q 4046 4 patients patient NNS cord-006870-f5w6fw6q 4046 5 waiting wait VBG cord-006870-f5w6fw6q 4046 6 for for IN cord-006870-f5w6fw6q 4046 7 the the DT cord-006870-f5w6fw6q 4046 8 study study NN cord-006870-f5w6fw6q 4046 9 dropped drop VBD cord-006870-f5w6fw6q 4046 10 from from IN cord-006870-f5w6fw6q 4046 11 1.6 1.6 CD cord-006870-f5w6fw6q 4046 12 to to TO cord-006870-f5w6fw6q 4046 13 0.3 0.3 CD cord-006870-f5w6fw6q 4046 14 per per IN cord-006870-f5w6fw6q 4046 15 week week NN cord-006870-f5w6fw6q 4046 16 . . . cord-006870-f5w6fw6q 4047 1 By by IN cord-006870-f5w6fw6q 4047 2 annualizing annualize VBG cord-006870-f5w6fw6q 4047 3 this this DT cord-006870-f5w6fw6q 4047 4 data data NN cord-006870-f5w6fw6q 4047 5 , , , cord-006870-f5w6fw6q 4047 6 the the DT cord-006870-f5w6fw6q 4047 7 change change NN cord-006870-f5w6fw6q 4047 8 has have VBZ cord-006870-f5w6fw6q 4047 9 created create VBN cord-006870-f5w6fw6q 4047 10 238 238 CD cord-006870-f5w6fw6q 4047 11 new new JJ cord-006870-f5w6fw6q 4047 12 available available JJ cord-006870-f5w6fw6q 4047 13 bed bed NN cord-006870-f5w6fw6q 4047 14 days day NNS cord-006870-f5w6fw6q 4047 15 , , , cord-006870-f5w6fw6q 4047 16 38 38 CD cord-006870-f5w6fw6q 4047 17 additional additional JJ cord-006870-f5w6fw6q 4047 18 patient patient NN cord-006870-f5w6fw6q 4047 19 encounters encounter NNS cord-006870-f5w6fw6q 4047 20 and and CC cord-006870-f5w6fw6q 4047 21 an an DT cord-006870-f5w6fw6q 4047 22 incremental incremental JJ cord-006870-f5w6fw6q 4047 23 annual annual JJ cord-006870-f5w6fw6q 4047 24 contribution contribution NN cord-006870-f5w6fw6q 4047 25 margin margin NN cord-006870-f5w6fw6q 4047 26 of of IN cord-006870-f5w6fw6q 4047 27 $ $ $ cord-006870-f5w6fw6q 4047 28 381 381 CD cord-006870-f5w6fw6q 4047 29 , , , cord-006870-f5w6fw6q 4047 30 425 425 CD cord-006870-f5w6fw6q 4047 31 . . . cord-006870-f5w6fw6q 4048 1 With with IN cord-006870-f5w6fw6q 4048 2 the the DT cord-006870-f5w6fw6q 4048 3 appointment appointment NN cord-006870-f5w6fw6q 4048 4 time time NN cord-006870-f5w6fw6q 4048 5 consistent consistent JJ cord-006870-f5w6fw6q 4048 6 , , , cord-006870-f5w6fw6q 4048 7 the the DT cord-006870-f5w6fw6q 4048 8 nurse nurse NN cord-006870-f5w6fw6q 4048 9 is be VBZ cord-006870-f5w6fw6q 4048 10 able able JJ cord-006870-f5w6fw6q 4048 11 to to TO cord-006870-f5w6fw6q 4048 12 plan plan VB cord-006870-f5w6fw6q 4048 13 patient patient JJ cord-006870-f5w6fw6q 4048 14 care care NN cord-006870-f5w6fw6q 4048 15 around around IN cord-006870-f5w6fw6q 4048 16 the the DT cord-006870-f5w6fw6q 4048 17 study study NN cord-006870-f5w6fw6q 4048 18 , , , cord-006870-f5w6fw6q 4048 19 and and CC cord-006870-f5w6fw6q 4048 20 ensure ensure VB cord-006870-f5w6fw6q 4048 21 the the DT cord-006870-f5w6fw6q 4048 22 patient patient NN cord-006870-f5w6fw6q 4048 23 is be VBZ cord-006870-f5w6fw6q 4048 24 prepared prepare VBN cord-006870-f5w6fw6q 4048 25 and and CC cord-006870-f5w6fw6q 4048 26 not not RB cord-006870-f5w6fw6q 4048 27 delayed delay VBN cord-006870-f5w6fw6q 4048 28 for for IN cord-006870-f5w6fw6q 4048 29 the the DT cord-006870-f5w6fw6q 4048 30 study study NN cord-006870-f5w6fw6q 4048 31 . . . cord-006870-f5w6fw6q 4049 1 It -PRON- PRP cord-006870-f5w6fw6q 4049 2 has have VBZ cord-006870-f5w6fw6q 4049 3 also also RB cord-006870-f5w6fw6q 4049 4 allowed allow VBN cord-006870-f5w6fw6q 4049 5 , , , cord-006870-f5w6fw6q 4049 6 if if IN cord-006870-f5w6fw6q 4049 7 deemed deem VBN cord-006870-f5w6fw6q 4049 8 safe safe JJ cord-006870-f5w6fw6q 4049 9 for for IN cord-006870-f5w6fw6q 4049 10 the the DT cord-006870-f5w6fw6q 4049 11 patient patient NN cord-006870-f5w6fw6q 4049 12 to to TO cord-006870-f5w6fw6q 4049 13 swallow swallow VB cord-006870-f5w6fw6q 4049 14 , , , cord-006870-f5w6fw6q 4049 15 medications medication NNS cord-006870-f5w6fw6q 4049 16 to to TO cord-006870-f5w6fw6q 4049 17 be be VB cord-006870-f5w6fw6q 4049 18 changed change VBN cord-006870-f5w6fw6q 4049 19 from from IN cord-006870-f5w6fw6q 4049 20 the the DT cord-006870-f5w6fw6q 4049 21 intravenous intravenous JJ cord-006870-f5w6fw6q 4049 22 route route NN cord-006870-f5w6fw6q 4049 23 to to IN cord-006870-f5w6fw6q 4049 24 the the DT cord-006870-f5w6fw6q 4049 25 oral oral JJ cord-006870-f5w6fw6q 4049 26 route route NN cord-006870-f5w6fw6q 4049 27 earlier early RBR cord-006870-f5w6fw6q 4049 28 , , , cord-006870-f5w6fw6q 4049 29 and and CC cord-006870-f5w6fw6q 4049 30 earlier early JJR cord-006870-f5w6fw6q 4049 31 determination determination NN cord-006870-f5w6fw6q 4049 32 of of IN cord-006870-f5w6fw6q 4049 33 safe safe JJ cord-006870-f5w6fw6q 4049 34 feeding feeding NN cord-006870-f5w6fw6q 4049 35 and and CC cord-006870-f5w6fw6q 4049 36 diet diet NN cord-006870-f5w6fw6q 4049 37 restrictions restriction NNS cord-006870-f5w6fw6q 4049 38 . . . cord-006870-f5w6fw6q 4050 1 We -PRON- PRP cord-006870-f5w6fw6q 4050 2 previously previously RB cord-006870-f5w6fw6q 4050 3 reported report VBD cord-006870-f5w6fw6q 4050 4 outcome outcome NN cord-006870-f5w6fw6q 4050 5 for for IN cord-006870-f5w6fw6q 4050 6 children child NNS cord-006870-f5w6fw6q 4050 7 with with IN cord-006870-f5w6fw6q 4050 8 refractory refractory JJ cord-006870-f5w6fw6q 4050 9 and and CC cord-006870-f5w6fw6q 4050 10 super super JJ cord-006870-f5w6fw6q 4050 11 - - JJ cord-006870-f5w6fw6q 4050 12 refractory refractory JJ cord-006870-f5w6fw6q 4050 13 status status NN cord-006870-f5w6fw6q 4050 14 epilepticus epilepticus NN cord-006870-f5w6fw6q 4050 15 in in IN cord-006870-f5w6fw6q 4050 16 a a DT cord-006870-f5w6fw6q 4050 17 cohort cohort NN cord-006870-f5w6fw6q 4050 18 of of IN cord-006870-f5w6fw6q 4050 19 40 40 CD cord-006870-f5w6fw6q 4050 20 patients patient NNS cord-006870-f5w6fw6q 4050 21 . . . cord-006870-f5w6fw6q 4051 1 Mortality mortality NN cord-006870-f5w6fw6q 4051 2 was be VBD cord-006870-f5w6fw6q 4051 3 30 30 CD cord-006870-f5w6fw6q 4051 4 % % NN cord-006870-f5w6fw6q 4051 5 . . . cord-006870-f5w6fw6q 4052 1 25 25 CD cord-006870-f5w6fw6q 4052 2 % % NN cord-006870-f5w6fw6q 4052 3 of of IN cord-006870-f5w6fw6q 4052 4 survivors survivor NNS cord-006870-f5w6fw6q 4052 5 required require VBD cord-006870-f5w6fw6q 4052 6 new new JJ cord-006870-f5w6fw6q 4052 7 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4052 8 and/or and/or CC cord-006870-f5w6fw6q 4052 9 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 4052 10 tubes tube NNS cord-006870-f5w6fw6q 4052 11 . . . cord-006870-f5w6fw6q 4053 1 The the DT cord-006870-f5w6fw6q 4053 2 majority majority NN cord-006870-f5w6fw6q 4053 3 of of IN cord-006870-f5w6fw6q 4053 4 surviving survive VBG cord-006870-f5w6fw6q 4053 5 patients patient NNS cord-006870-f5w6fw6q 4053 6 experienced experience VBD cord-006870-f5w6fw6q 4053 7 some some DT cord-006870-f5w6fw6q 4053 8 degree degree NN cord-006870-f5w6fw6q 4053 9 of of IN cord-006870-f5w6fw6q 4053 10 disability disability NN cord-006870-f5w6fw6q 4053 11 at at IN cord-006870-f5w6fw6q 4053 12 discharge discharge NN cord-006870-f5w6fw6q 4053 13 as as IN cord-006870-f5w6fw6q 4053 14 determined determine VBN cord-006870-f5w6fw6q 4053 15 by by IN cord-006870-f5w6fw6q 4053 16 the the DT cord-006870-f5w6fw6q 4053 17 Pediatric Pediatric NNP cord-006870-f5w6fw6q 4053 18 Cerebral Cerebral NNP cord-006870-f5w6fw6q 4053 19 Performance Performance NNP cord-006870-f5w6fw6q 4053 20 Category Category NNP cord-006870-f5w6fw6q 4053 21 Scale Scale NNP cord-006870-f5w6fw6q 4053 22 ( ( -LRB- cord-006870-f5w6fw6q 4053 23 PCPC PCPC NNP cord-006870-f5w6fw6q 4053 24 ) ) -RRB- cord-006870-f5w6fw6q 4053 25 . . . cord-006870-f5w6fw6q 4054 1 Here here RB cord-006870-f5w6fw6q 4054 2 , , , cord-006870-f5w6fw6q 4054 3 we -PRON- PRP cord-006870-f5w6fw6q 4054 4 aimed aim VBD cord-006870-f5w6fw6q 4054 5 to to TO cord-006870-f5w6fw6q 4054 6 identify identify VB cord-006870-f5w6fw6q 4054 7 patient patient JJ cord-006870-f5w6fw6q 4054 8 factors factor NNS cord-006870-f5w6fw6q 4054 9 in in IN cord-006870-f5w6fw6q 4054 10 this this DT cord-006870-f5w6fw6q 4054 11 cohort cohort NN cord-006870-f5w6fw6q 4054 12 that that WDT cord-006870-f5w6fw6q 4054 13 were be VBD cord-006870-f5w6fw6q 4054 14 associated associate VBN cord-006870-f5w6fw6q 4054 15 with with IN cord-006870-f5w6fw6q 4054 16 a a DT cord-006870-f5w6fw6q 4054 17 decline decline NN cord-006870-f5w6fw6q 4054 18 in in IN cord-006870-f5w6fw6q 4054 19 functional functional JJ cord-006870-f5w6fw6q 4054 20 neurologic neurologic JJ cord-006870-f5w6fw6q 4054 21 outcome outcome NN cord-006870-f5w6fw6q 4054 22 at at IN cord-006870-f5w6fw6q 4054 23 discharge discharge NN cord-006870-f5w6fw6q 4054 24 . . . cord-006870-f5w6fw6q 4055 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 4055 2 chart chart NN cord-006870-f5w6fw6q 4055 3 review review NN cord-006870-f5w6fw6q 4055 4 of of IN cord-006870-f5w6fw6q 4055 5 children child NNS cord-006870-f5w6fw6q 4055 6 age age NN cord-006870-f5w6fw6q 4055 7 0 0 CD cord-006870-f5w6fw6q 4055 8 - - SYM cord-006870-f5w6fw6q 4055 9 19 19 CD cord-006870-f5w6fw6q 4055 10 years year NNS cord-006870-f5w6fw6q 4055 11 who who WP cord-006870-f5w6fw6q 4055 12 received receive VBD cord-006870-f5w6fw6q 4055 13 pentobarbital pentobarbital JJ cord-006870-f5w6fw6q 4055 14 infusion infusion NN cord-006870-f5w6fw6q 4055 15 for for IN cord-006870-f5w6fw6q 4055 16 status status NN cord-006870-f5w6fw6q 4055 17 epilepticus epilepticus NN cord-006870-f5w6fw6q 4055 18 in in IN cord-006870-f5w6fw6q 4055 19 the the DT cord-006870-f5w6fw6q 4055 20 pediatric pediatric JJ cord-006870-f5w6fw6q 4055 21 intensive intensive JJ cord-006870-f5w6fw6q 4055 22 care care NN cord-006870-f5w6fw6q 4055 23 unit unit NN cord-006870-f5w6fw6q 4055 24 of of IN cord-006870-f5w6fw6q 4055 25 a a DT cord-006870-f5w6fw6q 4055 26 large large JJ cord-006870-f5w6fw6q 4055 27 tertiary tertiary JJ cord-006870-f5w6fw6q 4055 28 children child NNS cord-006870-f5w6fw6q 4055 29 's 's POS cord-006870-f5w6fw6q 4055 30 hospital hospital NN cord-006870-f5w6fw6q 4055 31 from from IN cord-006870-f5w6fw6q 4055 32 2004 2004 CD cord-006870-f5w6fw6q 4055 33 - - SYM cord-006870-f5w6fw6q 4055 34 2015 2015 CD cord-006870-f5w6fw6q 4055 35 . . . cord-006870-f5w6fw6q 4056 1 Outcome outcome NN cord-006870-f5w6fw6q 4056 2 was be VBD cord-006870-f5w6fw6q 4056 3 defined define VBN cord-006870-f5w6fw6q 4056 4 using use VBG cord-006870-f5w6fw6q 4056 5 PCPC PCPC NNP cord-006870-f5w6fw6q 4056 6 at at IN cord-006870-f5w6fw6q 4056 7 admission admission NN cord-006870-f5w6fw6q 4056 8 and and CC cord-006870-f5w6fw6q 4056 9 discharge discharge NN cord-006870-f5w6fw6q 4056 10 . . . cord-006870-f5w6fw6q 4057 1 Potential potential JJ cord-006870-f5w6fw6q 4057 2 factors factor NNS cord-006870-f5w6fw6q 4057 3 associated associate VBN cord-006870-f5w6fw6q 4057 4 with with IN cord-006870-f5w6fw6q 4057 5 outcome outcome NN cord-006870-f5w6fw6q 4057 6 were be VBD cord-006870-f5w6fw6q 4057 7 evaluated evaluate VBN cord-006870-f5w6fw6q 4057 8 using use VBG cord-006870-f5w6fw6q 4057 9 Fisher Fisher NNP cord-006870-f5w6fw6q 4057 10 's 's POS cord-006870-f5w6fw6q 4057 11 exact exact JJ cord-006870-f5w6fw6q 4057 12 test test NN cord-006870-f5w6fw6q 4057 13 and and CC cord-006870-f5w6fw6q 4057 14 Wilcoxon Wilcoxon NNP cord-006870-f5w6fw6q 4057 15 rank rank VBP cord-006870-f5w6fw6q 4057 16 sum sum NN cord-006870-f5w6fw6q 4057 17 test test NN cord-006870-f5w6fw6q 4057 18 . . . cord-006870-f5w6fw6q 4058 1 40 40 CD cord-006870-f5w6fw6q 4058 2 children child NNS cord-006870-f5w6fw6q 4058 3 were be VBD cord-006870-f5w6fw6q 4058 4 included include VBN cord-006870-f5w6fw6q 4058 5 . . . cord-006870-f5w6fw6q 4059 1 PCPC PCPC NNP cord-006870-f5w6fw6q 4059 2 score score NN cord-006870-f5w6fw6q 4059 3 at at IN cord-006870-f5w6fw6q 4059 4 admission admission NN cord-006870-f5w6fw6q 4059 5 ( ( -LRB- cord-006870-f5w6fw6q 4059 6 p=0.0006 p=0.0006 NNP cord-006870-f5w6fw6q 4059 7 ) ) -RRB- cord-006870-f5w6fw6q 4059 8 , , , cord-006870-f5w6fw6q 4059 9 etiology etiology NN cord-006870-f5w6fw6q 4059 10 of of IN cord-006870-f5w6fw6q 4059 11 status status NN cord-006870-f5w6fw6q 4059 12 epilepticus epilepticus NN cord-006870-f5w6fw6q 4059 13 ( ( -LRB- cord-006870-f5w6fw6q 4059 14 p=0.015 p=0.015 NNP cord-006870-f5w6fw6q 4059 15 ) ) -RRB- cord-006870-f5w6fw6q 4059 16 , , , cord-006870-f5w6fw6q 4059 17 new new JJ cord-006870-f5w6fw6q 4059 18 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4059 19 ( ( -LRB- cord-006870-f5w6fw6q 4059 20 p=0.012 p=0.012 NNP cord-006870-f5w6fw6q 4059 21 ) ) -RRB- cord-006870-f5w6fw6q 4059 22 , , , cord-006870-f5w6fw6q 4059 23 and and CC cord-006870-f5w6fw6q 4059 24 new new JJ cord-006870-f5w6fw6q 4059 25 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 4059 26 tube tube NN cord-006870-f5w6fw6q 4059 27 ( ( -LRB- cord-006870-f5w6fw6q 4059 28 p=0.012 p=0.012 NNP cord-006870-f5w6fw6q 4059 29 ) ) -RRB- cord-006870-f5w6fw6q 4060 1 were be VBD cord-006870-f5w6fw6q 4060 2 all all DT cord-006870-f5w6fw6q 4060 3 significantly significantly RB cord-006870-f5w6fw6q 4060 4 associated associate VBN cord-006870-f5w6fw6q 4060 5 with with IN cord-006870-f5w6fw6q 4060 6 children child NNS cord-006870-f5w6fw6q 4060 7 were be VBD cord-006870-f5w6fw6q 4060 8 more more RBR cord-006870-f5w6fw6q 4060 9 likely likely JJ cord-006870-f5w6fw6q 4060 10 to to TO cord-006870-f5w6fw6q 4060 11 have have VB cord-006870-f5w6fw6q 4060 12 normal normal JJ cord-006870-f5w6fw6q 4060 13 baseline baseline JJ cord-006870-f5w6fw6q 4060 14 neurologic neurologic JJ cord-006870-f5w6fw6q 4060 15 function function NN cord-006870-f5w6fw6q 4060 16 and and CC cord-006870-f5w6fw6q 4060 17 more more RBR cord-006870-f5w6fw6q 4060 18 likely likely JJ cord-006870-f5w6fw6q 4060 19 to to TO cord-006870-f5w6fw6q 4060 20 have have VB cord-006870-f5w6fw6q 4060 21 febrile febrile JJ cord-006870-f5w6fw6q 4060 22 encephalitis encephalitis RB cord-006870-f5w6fw6q 4060 23 , , , cord-006870-f5w6fw6q 4060 24 stroke stroke NN cord-006870-f5w6fw6q 4060 25 / / SYM cord-006870-f5w6fw6q 4060 26 trauma trauma NN cord-006870-f5w6fw6q 4060 27 , , , cord-006870-f5w6fw6q 4060 28 or or CC cord-006870-f5w6fw6q 4060 29 hypoxic hypoxic JJ cord-006870-f5w6fw6q 4060 30 ischemic ischemic JJ cord-006870-f5w6fw6q 4060 31 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 4060 32 as as IN cord-006870-f5w6fw6q 4060 33 the the DT cord-006870-f5w6fw6q 4060 34 etiology etiology NN cord-006870-f5w6fw6q 4060 35 of of IN cord-006870-f5w6fw6q 4060 36 status status NN cord-006870-f5w6fw6q 4060 37 epilepticus epilepticus NN cord-006870-f5w6fw6q 4060 38 . . . cord-006870-f5w6fw6q 4061 1 Duration duration NN cord-006870-f5w6fw6q 4061 2 of of IN cord-006870-f5w6fw6q 4061 3 pentobarbital pentobarbital JJ cord-006870-f5w6fw6q 4061 4 infusion infusion NN cord-006870-f5w6fw6q 4061 5 ( ( -LRB- cord-006870-f5w6fw6q 4061 6 median median NN cord-006870-f5w6fw6q 4061 7 = = SYM cord-006870-f5w6fw6q 4061 8 8days 8days CD cord-006870-f5w6fw6q 4061 9 vs. vs. FW cord-006870-f5w6fw6q 4061 10 3days 3days LS cord-006870-f5w6fw6q 4061 11 ) ) -RRB- cord-006870-f5w6fw6q 4061 12 ( ( -LRB- cord-006870-f5w6fw6q 4061 13 p=0.005 p=0.005 NNP cord-006870-f5w6fw6q 4061 14 ) ) -RRB- cord-006870-f5w6fw6q 4061 15 and and CC cord-006870-f5w6fw6q 4061 16 duration duration NN cord-006870-f5w6fw6q 4061 17 of of IN cord-006870-f5w6fw6q 4061 18 hospital hospital NN cord-006870-f5w6fw6q 4061 19 admission admission NN cord-006870-f5w6fw6q 4061 20 ( ( -LRB- cord-006870-f5w6fw6q 4061 21 median median NN cord-006870-f5w6fw6q 4061 22 = = SYM cord-006870-f5w6fw6q 4061 23 1.48months 1.48months CD cord-006870-f5w6fw6q 4061 24 vs. vs. FW cord-006870-f5w6fw6q 4061 25 0.49months 0.49months CD cord-006870-f5w6fw6q 4061 26 ) ) -RRB- cord-006870-f5w6fw6q 4062 1 ( ( -LRB- cord-006870-f5w6fw6q 4062 2 p=0.005 p=0.005 NNP cord-006870-f5w6fw6q 4062 3 ) ) -RRB- cord-006870-f5w6fw6q 4062 4 were be VBD cord-006870-f5w6fw6q 4062 5 both both DT cord-006870-f5w6fw6q 4062 6 longer long RBR cord-006870-f5w6fw6q 4062 7 in in IN cord-006870-f5w6fw6q 4062 8 patients patient NNS cord-006870-f5w6fw6q 4062 9 who who WP cord-006870-f5w6fw6q 4062 10 had have VBD cord-006870-f5w6fw6q 4062 11 an an DT cord-006870-f5w6fw6q 4062 12 Admission Admission NNP cord-006870-f5w6fw6q 4062 13 PCPC PCPC NNP cord-006870-f5w6fw6q 4062 14 score score NN cord-006870-f5w6fw6q 4062 15 , , , cord-006870-f5w6fw6q 4062 16 etiology etiology NN cord-006870-f5w6fw6q 4062 17 of of IN cord-006870-f5w6fw6q 4062 18 status status NN cord-006870-f5w6fw6q 4062 19 epilepticus epilepticus NN cord-006870-f5w6fw6q 4062 20 , , , cord-006870-f5w6fw6q 4062 21 new new JJ cord-006870-f5w6fw6q 4062 22 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4062 23 and and CC cord-006870-f5w6fw6q 4062 24 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 4062 25 tube tube NN cord-006870-f5w6fw6q 4062 26 as as RB cord-006870-f5w6fw6q 4062 27 well well RB cord-006870-f5w6fw6q 4062 28 as as IN cord-006870-f5w6fw6q 4062 29 longer long JJR cord-006870-f5w6fw6q 4062 30 duration duration NN cord-006870-f5w6fw6q 4062 31 of of IN cord-006870-f5w6fw6q 4062 32 pentobarbital pentobarbital JJ cord-006870-f5w6fw6q 4062 33 infusion infusion NN cord-006870-f5w6fw6q 4062 34 and and CC cord-006870-f5w6fw6q 4062 35 longer long JJR cord-006870-f5w6fw6q 4062 36 hospital hospital NN cord-006870-f5w6fw6q 4062 37 stay stay NN cord-006870-f5w6fw6q 4062 38 were be VBD cord-006870-f5w6fw6q 4062 39 significantly significantly RB cord-006870-f5w6fw6q 4062 40 associated associate VBN cord-006870-f5w6fw6q 4062 41 with with IN cord-006870-f5w6fw6q 4062 42 a a DT cord-006870-f5w6fw6q 4062 43 decline decline NN cord-006870-f5w6fw6q 4062 44 in in IN cord-006870-f5w6fw6q 4062 45 functional functional JJ cord-006870-f5w6fw6q 4062 46 neurologic neurologic JJ cord-006870-f5w6fw6q 4062 47 outcome outcome NN cord-006870-f5w6fw6q 4062 48 at at IN cord-006870-f5w6fw6q 4062 49 hospital hospital NN cord-006870-f5w6fw6q 4062 50 discharge discharge NN cord-006870-f5w6fw6q 4062 51 in in IN cord-006870-f5w6fw6q 4062 52 children child NNS cord-006870-f5w6fw6q 4062 53 with with IN cord-006870-f5w6fw6q 4062 54 refractory refractory JJ cord-006870-f5w6fw6q 4062 55 and and CC cord-006870-f5w6fw6q 4062 56 superrefractory superrefractory JJ cord-006870-f5w6fw6q 4062 57 status status NN cord-006870-f5w6fw6q 4062 58 epilepticus epilepticus NN cord-006870-f5w6fw6q 4062 59 . . . cord-006870-f5w6fw6q 4063 1 Status status NN cord-006870-f5w6fw6q 4063 2 epilepticus epilepticus NN cord-006870-f5w6fw6q 4063 3 ( ( -LRB- cord-006870-f5w6fw6q 4063 4 SE SE NNP cord-006870-f5w6fw6q 4063 5 ) ) -RRB- cord-006870-f5w6fw6q 4063 6 is be VBZ cord-006870-f5w6fw6q 4063 7 the the DT cord-006870-f5w6fw6q 4063 8 most most RBS cord-006870-f5w6fw6q 4063 9 common common JJ cord-006870-f5w6fw6q 4063 10 pediatric pediatric JJ cord-006870-f5w6fw6q 4063 11 neurological neurological JJ cord-006870-f5w6fw6q 4063 12 , , , cord-006870-f5w6fw6q 4063 13 and and CC cord-006870-f5w6fw6q 4063 14 super super JJ cord-006870-f5w6fw6q 4063 15 - - JJ cord-006870-f5w6fw6q 4063 16 refractory refractory JJ cord-006870-f5w6fw6q 4063 17 SE SE NNP cord-006870-f5w6fw6q 4063 18 is be VBZ cord-006870-f5w6fw6q 4063 19 a a DT cord-006870-f5w6fw6q 4063 20 lifethreatening lifethreatening JJ cord-006870-f5w6fw6q 4063 21 form form NN cord-006870-f5w6fw6q 4063 22 of of IN cord-006870-f5w6fw6q 4063 23 SE SE NNP cord-006870-f5w6fw6q 4063 24 that that WDT cord-006870-f5w6fw6q 4063 25 continues continue VBZ cord-006870-f5w6fw6q 4063 26 or or CC cord-006870-f5w6fw6q 4063 27 recurs recur VBZ cord-006870-f5w6fw6q 4063 28 for for IN cord-006870-f5w6fw6q 4063 29 more more JJR cord-006870-f5w6fw6q 4063 30 than than IN cord-006870-f5w6fw6q 4063 31 24 24 CD cord-006870-f5w6fw6q 4063 32 hours hour NNS cord-006870-f5w6fw6q 4063 33 despite despite IN cord-006870-f5w6fw6q 4063 34 multiple multiple JJ cord-006870-f5w6fw6q 4063 35 therapeutic therapeutic JJ cord-006870-f5w6fw6q 4063 36 interventions intervention NNS cord-006870-f5w6fw6q 4063 37 . . . cord-006870-f5w6fw6q 4064 1 This this DT cord-006870-f5w6fw6q 4064 2 population population NN cord-006870-f5w6fw6q 4064 3 - - HYPH cord-006870-f5w6fw6q 4064 4 based base VBN cord-006870-f5w6fw6q 4064 5 study study NN cord-006870-f5w6fw6q 4064 6 investigated investigate VBD cord-006870-f5w6fw6q 4064 7 pediatric pediatric JJ cord-006870-f5w6fw6q 4064 8 SE SE NNP cord-006870-f5w6fw6q 4064 9 and and CC cord-006870-f5w6fw6q 4064 10 SRSE SRSE NNP cord-006870-f5w6fw6q 4064 11 admissions admission NNS cord-006870-f5w6fw6q 4064 12 in in IN cord-006870-f5w6fw6q 4064 13 Germany Germany NNP cord-006870-f5w6fw6q 4064 14 . . . cord-006870-f5w6fw6q 4065 1 Pediatric pediatric JJ cord-006870-f5w6fw6q 4065 2 ( ( -LRB- cord-006870-f5w6fw6q 4065 3 age age NN cord-006870-f5w6fw6q 4065 4 0 0 CD cord-006870-f5w6fw6q 4065 5 - - SYM cord-006870-f5w6fw6q 4065 6 18 18 CD cord-006870-f5w6fw6q 4065 7 years year NNS cord-006870-f5w6fw6q 4065 8 ) ) -RRB- cord-006870-f5w6fw6q 4065 9 admissions admission NNS cord-006870-f5w6fw6q 4065 10 between between IN cord-006870-f5w6fw6q 4065 11 2008 2008 CD cord-006870-f5w6fw6q 4065 12 - - SYM cord-006870-f5w6fw6q 4065 13 2015 2015 CD cord-006870-f5w6fw6q 4065 14 were be VBD cord-006870-f5w6fw6q 4065 15 identified identify VBN cord-006870-f5w6fw6q 4065 16 in in IN cord-006870-f5w6fw6q 4065 17 the the DT cord-006870-f5w6fw6q 4065 18 Arvato Arvato NNP cord-006870-f5w6fw6q 4065 19 Health Health NNP cord-006870-f5w6fw6q 4065 20 Analytics Analytics NNP cord-006870-f5w6fw6q 4065 21 database database NN cord-006870-f5w6fw6q 4065 22 . . . cord-006870-f5w6fw6q 4066 1 SE SE NNP cord-006870-f5w6fw6q 4066 2 , , , cord-006870-f5w6fw6q 4066 3 epilepsy epilepsy NN cord-006870-f5w6fw6q 4066 4 , , , cord-006870-f5w6fw6q 4066 5 and and CC cord-006870-f5w6fw6q 4066 6 febrile febrile JJ cord-006870-f5w6fw6q 4066 7 seizure seizure NN cord-006870-f5w6fw6q 4066 8 cases case NNS cord-006870-f5w6fw6q 4066 9 were be VBD cord-006870-f5w6fw6q 4066 10 identified identify VBN cord-006870-f5w6fw6q 4066 11 using use VBG cord-006870-f5w6fw6q 4066 12 a a DT cord-006870-f5w6fw6q 4066 13 modification modification NN cord-006870-f5w6fw6q 4066 14 of of IN cord-006870-f5w6fw6q 4066 15 a a DT cord-006870-f5w6fw6q 4066 16 previouslypublished previouslypublished NN cord-006870-f5w6fw6q 4066 17 algorithm algorithm NN cord-006870-f5w6fw6q 4066 18 based base VBN cord-006870-f5w6fw6q 4066 19 on on IN cord-006870-f5w6fw6q 4066 20 ICD-10 icd-10 JJ cord-006870-f5w6fw6q 4066 21 diagnosis diagnosis NN cord-006870-f5w6fw6q 4066 22 codes code NNS cord-006870-f5w6fw6q 4066 23 ( ( -LRB- cord-006870-f5w6fw6q 4066 24 G40 G40 NNP cord-006870-f5w6fw6q 4066 25 , , , cord-006870-f5w6fw6q 4066 26 G41 G41 NNP cord-006870-f5w6fw6q 4066 27 , , , cord-006870-f5w6fw6q 4066 28 and and CC cord-006870-f5w6fw6q 4066 29 R56 R56 NNP cord-006870-f5w6fw6q 4066 30 ) ) -RRB- cord-006870-f5w6fw6q 4066 31 and and CC cord-006870-f5w6fw6q 4066 32 coding code VBG cord-006870-f5w6fw6q 4066 33 for for IN cord-006870-f5w6fw6q 4066 34 ventilator ventilator NN cord-006870-f5w6fw6q 4066 35 and and CC cord-006870-f5w6fw6q 4066 36 intensive intensive JJ cord-006870-f5w6fw6q 4066 37 care care NN cord-006870-f5w6fw6q 4066 38 unit unit NN cord-006870-f5w6fw6q 4066 39 use use NN cord-006870-f5w6fw6q 4066 40 . . . cord-006870-f5w6fw6q 4067 1 Based base VBN cord-006870-f5w6fw6q 4067 2 on on IN cord-006870-f5w6fw6q 4067 3 primary primary JJ cord-006870-f5w6fw6q 4067 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 4067 5 , , , cord-006870-f5w6fw6q 4067 6 prior prior JJ cord-006870-f5w6fw6q 4067 7 epilepsy epilepsy NN cord-006870-f5w6fw6q 4067 8 status status NN cord-006870-f5w6fw6q 4067 9 , , , cord-006870-f5w6fw6q 4067 10 and and CC cord-006870-f5w6fw6q 4067 11 ventilation ventilation NN cord-006870-f5w6fw6q 4067 12 SE SE NNP cord-006870-f5w6fw6q 4067 13 was be VBD cord-006870-f5w6fw6q 4067 14 subclassified subclassifie VBN cord-006870-f5w6fw6q 4067 15 as as IN cord-006870-f5w6fw6q 4067 16 non non JJ cord-006870-f5w6fw6q 4067 17 - - JJ cord-006870-f5w6fw6q 4067 18 refractory refractory JJ cord-006870-f5w6fw6q 4067 19 , , , cord-006870-f5w6fw6q 4067 20 refractory refractory JJ cord-006870-f5w6fw6q 4067 21 ( ( -LRB- cord-006870-f5w6fw6q 4067 22 RSE RSE NNP cord-006870-f5w6fw6q 4067 23 ) ) -RRB- cord-006870-f5w6fw6q 4067 24 , , , cord-006870-f5w6fw6q 4067 25 and and CC cord-006870-f5w6fw6q 4067 26 super super JJ cord-006870-f5w6fw6q 4067 27 - - JJ cord-006870-f5w6fw6q 4067 28 refractory refractory JJ cord-006870-f5w6fw6q 4067 29 ( ( -LRB- cord-006870-f5w6fw6q 4067 30 SRSE SRSE NNP cord-006870-f5w6fw6q 4067 31 ) ) -RRB- cord-006870-f5w6fw6q 4067 32 . . . cord-006870-f5w6fw6q 4068 1 Inpatient inpatient JJ cord-006870-f5w6fw6q 4068 2 mortality mortality NN cord-006870-f5w6fw6q 4068 3 , , , cord-006870-f5w6fw6q 4068 4 costs cost NNS cord-006870-f5w6fw6q 4068 5 , , , cord-006870-f5w6fw6q 4068 6 length length NN cord-006870-f5w6fw6q 4068 7 - - HYPH cord-006870-f5w6fw6q 4068 8 of of IN cord-006870-f5w6fw6q 4068 9 - - HYPH cord-006870-f5w6fw6q 4068 10 stay stay NN cord-006870-f5w6fw6q 4068 11 ( ( -LRB- cord-006870-f5w6fw6q 4068 12 LOS LOS NNP cord-006870-f5w6fw6q 4068 13 ) ) -RRB- cord-006870-f5w6fw6q 4068 14 , , , cord-006870-f5w6fw6q 4068 15 and and CC cord-006870-f5w6fw6q 4068 16 discharge discharge NN cord-006870-f5w6fw6q 4068 17 disposition disposition NN cord-006870-f5w6fw6q 4068 18 were be VBD cord-006870-f5w6fw6q 4068 19 assessed assess VBN cord-006870-f5w6fw6q 4068 20 overall overall RB cord-006870-f5w6fw6q 4068 21 and and CC cord-006870-f5w6fw6q 4068 22 for for IN cord-006870-f5w6fw6q 4068 23 RSE RSE NNP cord-006870-f5w6fw6q 4068 24 and and CC cord-006870-f5w6fw6q 4068 25 SRSE SRSE NNP cord-006870-f5w6fw6q 4068 26 . . . cord-006870-f5w6fw6q 4069 1 The the DT cord-006870-f5w6fw6q 4069 2 algorithm algorithm NN cord-006870-f5w6fw6q 4069 3 identified identify VBD cord-006870-f5w6fw6q 4069 4 11,693 11,693 CD cord-006870-f5w6fw6q 4069 5 seizure seizure NN cord-006870-f5w6fw6q 4069 6 - - HYPH cord-006870-f5w6fw6q 4069 7 related relate VBN cord-006870-f5w6fw6q 4069 8 admissions admission NNS cord-006870-f5w6fw6q 4069 9 and and CC cord-006870-f5w6fw6q 4069 10 classified classify VBD cord-006870-f5w6fw6q 4069 11 4 4 CD cord-006870-f5w6fw6q 4069 12 % % NN cord-006870-f5w6fw6q 4069 13 as as IN cord-006870-f5w6fw6q 4069 14 SE SE NNP cord-006870-f5w6fw6q 4069 15 , , , cord-006870-f5w6fw6q 4069 16 of of IN cord-006870-f5w6fw6q 4069 17 which which WDT cord-006870-f5w6fw6q 4069 18 22.9 22.9 CD cord-006870-f5w6fw6q 4069 19 % % NN cord-006870-f5w6fw6q 4069 20 were be VBD cord-006870-f5w6fw6q 4069 21 RSE RSE NNP cord-006870-f5w6fw6q 4069 22 and and CC cord-006870-f5w6fw6q 4069 23 13.1 13.1 CD cord-006870-f5w6fw6q 4069 24 % % NN cord-006870-f5w6fw6q 4069 25 were be VBD cord-006870-f5w6fw6q 4069 26 SRSE SRSE NNP cord-006870-f5w6fw6q 4069 27 . . . cord-006870-f5w6fw6q 4070 1 The the DT cord-006870-f5w6fw6q 4070 2 RSE rse NN cord-006870-f5w6fw6q 4070 3 frequency frequency NN cord-006870-f5w6fw6q 4070 4 was be VBD cord-006870-f5w6fw6q 4070 5 highest high JJS cord-006870-f5w6fw6q 4070 6 among among IN cord-006870-f5w6fw6q 4070 7 ages age NNS cord-006870-f5w6fw6q 4070 8 1 1 CD cord-006870-f5w6fw6q 4070 9 - - SYM cord-006870-f5w6fw6q 4070 10 6 6 CD cord-006870-f5w6fw6q 4070 11 . . . cord-006870-f5w6fw6q 4071 1 The the DT cord-006870-f5w6fw6q 4071 2 incidence incidence NN cord-006870-f5w6fw6q 4071 3 of of IN cord-006870-f5w6fw6q 4071 4 cases case NNS cord-006870-f5w6fw6q 4071 5 classified classify VBN cord-006870-f5w6fw6q 4071 6 as as IN cord-006870-f5w6fw6q 4071 7 SRSE SRSE NNP cord-006870-f5w6fw6q 4071 8 peaked peak VBD cord-006870-f5w6fw6q 4071 9 among among IN cord-006870-f5w6fw6q 4071 10 newborns newborn NNS cord-006870-f5w6fw6q 4071 11 ( ( -LRB- cord-006870-f5w6fw6q 4071 12 age<1 age<1 NN cord-006870-f5w6fw6q 4071 13 year year NN cord-006870-f5w6fw6q 4071 14 ) ) -RRB- cord-006870-f5w6fw6q 4071 15 , , , cord-006870-f5w6fw6q 4071 16 decreasing decrease VBG cord-006870-f5w6fw6q 4071 17 between between IN cord-006870-f5w6fw6q 4071 18 ages age NNS cord-006870-f5w6fw6q 4071 19 1 1 CD cord-006870-f5w6fw6q 4071 20 - - SYM cord-006870-f5w6fw6q 4071 21 7 7 CD cord-006870-f5w6fw6q 4071 22 years year NNS cord-006870-f5w6fw6q 4071 23 . . . cord-006870-f5w6fw6q 4072 1 Cases case NNS cord-006870-f5w6fw6q 4072 2 classified classify VBN cord-006870-f5w6fw6q 4072 3 as as IN cord-006870-f5w6fw6q 4072 4 SE SE NNP cord-006870-f5w6fw6q 4072 5 accounted account VBD cord-006870-f5w6fw6q 4072 6 for for IN cord-006870-f5w6fw6q 4072 7 23.0 23.0 CD cord-006870-f5w6fw6q 4072 8 % % NN cord-006870-f5w6fw6q 4072 9 of of IN cord-006870-f5w6fw6q 4072 10 total total JJ cord-006870-f5w6fw6q 4072 11 costs cost NNS cord-006870-f5w6fw6q 4072 12 associated associate VBN cord-006870-f5w6fw6q 4072 13 with with IN cord-006870-f5w6fw6q 4072 14 seizure seizure NN cord-006870-f5w6fw6q 4072 15 - - HYPH cord-006870-f5w6fw6q 4072 16 related relate VBN cord-006870-f5w6fw6q 4072 17 hospitalizations hospitalization NNS cord-006870-f5w6fw6q 4072 18 . . . cord-006870-f5w6fw6q 4073 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4073 2 exhibited exhibit VBD cord-006870-f5w6fw6q 4073 3 the the DT cord-006870-f5w6fw6q 4073 4 highest high JJS cord-006870-f5w6fw6q 4073 5 per per IN cord-006870-f5w6fw6q 4073 6 case case NN cord-006870-f5w6fw6q 4073 7 cost cost NN cord-006870-f5w6fw6q 4073 8 ( ( -LRB- cord-006870-f5w6fw6q 4073 9 mean mean VB cord-006870-f5w6fw6q 4073 10 € € $ cord-006870-f5w6fw6q 4073 11 77,316 77,316 CD cord-006870-f5w6fw6q 4073 12 ) ) -RRB- cord-006870-f5w6fw6q 4073 13 , , , cord-006870-f5w6fw6q 4073 14 amounting amount VBG cord-006870-f5w6fw6q 4073 15 to to IN cord-006870-f5w6fw6q 4073 16 58.0 58.0 CD cord-006870-f5w6fw6q 4073 17 % % NN cord-006870-f5w6fw6q 4073 18 of of IN cord-006870-f5w6fw6q 4073 19 all all DT cord-006870-f5w6fw6q 4073 20 SE SE NNP cord-006870-f5w6fw6q 4073 21 costs cost NNS cord-006870-f5w6fw6q 4073 22 , , , cord-006870-f5w6fw6q 4073 23 and and CC cord-006870-f5w6fw6q 4073 24 these these DT cord-006870-f5w6fw6q 4073 25 costs cost NNS cord-006870-f5w6fw6q 4073 26 correlated correlate VBN cord-006870-f5w6fw6q 4073 27 with with IN cord-006870-f5w6fw6q 4073 28 the the DT cord-006870-f5w6fw6q 4073 29 highest high JJS cord-006870-f5w6fw6q 4073 30 LOS LOS NNP cord-006870-f5w6fw6q 4073 31 ( ( -LRB- cord-006870-f5w6fw6q 4073 32 median median JJ cord-006870-f5w6fw6q 4073 33 44.5 44.5 CD cord-006870-f5w6fw6q 4073 34 days day NNS cord-006870-f5w6fw6q 4073 35 ) ) -RRB- cord-006870-f5w6fw6q 4073 36 . . . cord-006870-f5w6fw6q 4074 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4074 2 was be VBD cord-006870-f5w6fw6q 4074 3 associated associate VBN cord-006870-f5w6fw6q 4074 4 with with IN cord-006870-f5w6fw6q 4074 5 greater great JJR cord-006870-f5w6fw6q 4074 6 mortality mortality NN cord-006870-f5w6fw6q 4074 7 ( ( -LRB- cord-006870-f5w6fw6q 4074 8 11.7 11.7 CD cord-006870-f5w6fw6q 4074 9 % % NN cord-006870-f5w6fw6q 4074 10 ) ) -RRB- cord-006870-f5w6fw6q 4075 1 Cases case NNS cord-006870-f5w6fw6q 4075 2 classified classify VBN cord-006870-f5w6fw6q 4075 3 as as IN cord-006870-f5w6fw6q 4075 4 SRSE SRSE NNP cord-006870-f5w6fw6q 4075 5 accounted account VBD cord-006870-f5w6fw6q 4075 6 for for IN cord-006870-f5w6fw6q 4075 7 14.2 14.2 CD cord-006870-f5w6fw6q 4075 8 % % NN cord-006870-f5w6fw6q 4075 9 of of IN cord-006870-f5w6fw6q 4075 10 all all DT cord-006870-f5w6fw6q 4075 11 pediatric pediatric JJ cord-006870-f5w6fw6q 4075 12 seizure seizure NN cord-006870-f5w6fw6q 4075 13 - - HYPH cord-006870-f5w6fw6q 4075 14 related relate VBN cord-006870-f5w6fw6q 4075 15 costs cost NNS cord-006870-f5w6fw6q 4075 16 , , , cord-006870-f5w6fw6q 4075 17 despite despite IN cord-006870-f5w6fw6q 4075 18 representing represent VBG cord-006870-f5w6fw6q 4075 19 only only RB cord-006870-f5w6fw6q 4075 20 0.5 0.5 CD cord-006870-f5w6fw6q 4075 21 % % NN cord-006870-f5w6fw6q 4075 22 of of IN cord-006870-f5w6fw6q 4075 23 admissions admission NNS cord-006870-f5w6fw6q 4075 24 . . . cord-006870-f5w6fw6q 4076 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4076 2 was be VBD cord-006870-f5w6fw6q 4076 3 associated associate VBN cord-006870-f5w6fw6q 4076 4 with with IN cord-006870-f5w6fw6q 4076 5 the the DT cord-006870-f5w6fw6q 4076 6 highest high JJS cord-006870-f5w6fw6q 4076 7 LOS LOS NNP cord-006870-f5w6fw6q 4076 8 and and CC cord-006870-f5w6fw6q 4076 9 mortality mortality NN cord-006870-f5w6fw6q 4076 10 rate rate NN cord-006870-f5w6fw6q 4076 11 . . . cord-006870-f5w6fw6q 4077 1 These these DT cord-006870-f5w6fw6q 4077 2 results result NNS cord-006870-f5w6fw6q 4077 3 highlight highlight VBP cord-006870-f5w6fw6q 4077 4 the the DT cord-006870-f5w6fw6q 4077 5 burden burden NN cord-006870-f5w6fw6q 4077 6 of of IN cord-006870-f5w6fw6q 4077 7 illness illness NN cord-006870-f5w6fw6q 4077 8 associated associate VBN cord-006870-f5w6fw6q 4077 9 with with IN cord-006870-f5w6fw6q 4077 10 SRSE SRSE NNP cord-006870-f5w6fw6q 4077 11 and and CC cord-006870-f5w6fw6q 4077 12 suggest suggest VBP cord-006870-f5w6fw6q 4077 13 that that IN cord-006870-f5w6fw6q 4077 14 optimization optimization NN cord-006870-f5w6fw6q 4077 15 of of IN cord-006870-f5w6fw6q 4077 16 SRSE SRSE NNP cord-006870-f5w6fw6q 4077 17 management management NN cord-006870-f5w6fw6q 4077 18 has have VBZ cord-006870-f5w6fw6q 4077 19 the the DT cord-006870-f5w6fw6q 4077 20 potential potential NN cord-006870-f5w6fw6q 4077 21 to to TO cord-006870-f5w6fw6q 4077 22 improve improve VB cord-006870-f5w6fw6q 4077 23 outcomes outcome NNS cord-006870-f5w6fw6q 4077 24 and and CC cord-006870-f5w6fw6q 4077 25 reduce reduce VB cord-006870-f5w6fw6q 4077 26 costs cost NNS cord-006870-f5w6fw6q 4077 27 . . . cord-006870-f5w6fw6q 4078 1 Despite despite IN cord-006870-f5w6fw6q 4078 2 its -PRON- PRP$ cord-006870-f5w6fw6q 4078 3 more more RBR cord-006870-f5w6fw6q 4078 4 routine routine JJ cord-006870-f5w6fw6q 4078 5 use use NN cord-006870-f5w6fw6q 4078 6 and and CC cord-006870-f5w6fw6q 4078 7 the the DT cord-006870-f5w6fw6q 4078 8 recognition recognition NN cord-006870-f5w6fw6q 4078 9 that that IN cord-006870-f5w6fw6q 4078 10 MRI MRI NNP cord-006870-f5w6fw6q 4078 11 provides provide VBZ cord-006870-f5w6fw6q 4078 12 superior superior JJ cord-006870-f5w6fw6q 4078 13 detection detection NN cord-006870-f5w6fw6q 4078 14 of of IN cord-006870-f5w6fw6q 4078 15 traumatic traumatic JJ cord-006870-f5w6fw6q 4078 16 brain brain NN cord-006870-f5w6fw6q 4078 17 injuries injury NNS cord-006870-f5w6fw6q 4078 18 , , , cord-006870-f5w6fw6q 4078 19 there there EX cord-006870-f5w6fw6q 4078 20 has have VBZ cord-006870-f5w6fw6q 4078 21 been be VBN cord-006870-f5w6fw6q 4078 22 little little RB cord-006870-f5w6fw6q 4078 23 written write VBN cord-006870-f5w6fw6q 4078 24 about about IN cord-006870-f5w6fw6q 4078 25 how how WRB cord-006870-f5w6fw6q 4078 26 MRI MRI NNP cord-006870-f5w6fw6q 4078 27 might may MD cord-006870-f5w6fw6q 4078 28 affect affect VB cord-006870-f5w6fw6q 4078 29 the the DT cord-006870-f5w6fw6q 4078 30 acute acute JJ cord-006870-f5w6fw6q 4078 31 management management NN cord-006870-f5w6fw6q 4078 32 of of IN cord-006870-f5w6fw6q 4078 33 trauma trauma NN cord-006870-f5w6fw6q 4078 34 patients patient NNS cord-006870-f5w6fw6q 4078 35 . . . cord-006870-f5w6fw6q 4079 1 We -PRON- PRP cord-006870-f5w6fw6q 4079 2 sought seek VBD cord-006870-f5w6fw6q 4079 3 to to TO cord-006870-f5w6fw6q 4079 4 describe describe VB cord-006870-f5w6fw6q 4079 5 MRI MRI NNP cord-006870-f5w6fw6q 4079 6 findings finding NNS cord-006870-f5w6fw6q 4079 7 in in IN cord-006870-f5w6fw6q 4079 8 a a DT cord-006870-f5w6fw6q 4079 9 cohort cohort NN cord-006870-f5w6fw6q 4079 10 of of IN cord-006870-f5w6fw6q 4079 11 children child NNS cord-006870-f5w6fw6q 4079 12 admitted admit VBN cord-006870-f5w6fw6q 4079 13 to to IN cord-006870-f5w6fw6q 4079 14 the the DT cord-006870-f5w6fw6q 4079 15 PICU PICU NNP cord-006870-f5w6fw6q 4079 16 with with IN cord-006870-f5w6fw6q 4079 17 TBI TBI NNP cord-006870-f5w6fw6q 4079 18 and and CC cord-006870-f5w6fw6q 4079 19 to to TO cord-006870-f5w6fw6q 4079 20 extend extend VB cord-006870-f5w6fw6q 4079 21 comparisons comparison NNS cord-006870-f5w6fw6q 4079 22 between between IN cord-006870-f5w6fw6q 4079 23 CT CT NNP cord-006870-f5w6fw6q 4079 24 and and CC cord-006870-f5w6fw6q 4079 25 MRI MRI NNP cord-006870-f5w6fw6q 4079 26 in in IN cord-006870-f5w6fw6q 4079 27 acute acute JJ cord-006870-f5w6fw6q 4079 28 trauma trauma NN cord-006870-f5w6fw6q 4079 29 . . . cord-006870-f5w6fw6q 4080 1 A a DT cord-006870-f5w6fw6q 4080 2 secondary secondary JJ cord-006870-f5w6fw6q 4080 3 aim aim NN cord-006870-f5w6fw6q 4080 4 was be VBD cord-006870-f5w6fw6q 4080 5 to to TO cord-006870-f5w6fw6q 4080 6 quantify quantify VB cord-006870-f5w6fw6q 4080 7 in in IN cord-006870-f5w6fw6q 4080 8 what what WDT cord-006870-f5w6fw6q 4080 9 ways way NNS cord-006870-f5w6fw6q 4080 10 MRI MRI NNP cord-006870-f5w6fw6q 4080 11 findings finding NNS cord-006870-f5w6fw6q 4080 12 influenced influence VBD cord-006870-f5w6fw6q 4080 13 clinical clinical JJ cord-006870-f5w6fw6q 4080 14 management management NN cord-006870-f5w6fw6q 4080 15 in in IN cord-006870-f5w6fw6q 4080 16 this this DT cord-006870-f5w6fw6q 4080 17 cohort cohort NN cord-006870-f5w6fw6q 4080 18 . . . cord-006870-f5w6fw6q 4081 1 We -PRON- PRP cord-006870-f5w6fw6q 4081 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 4081 3 identified identify VBD cord-006870-f5w6fw6q 4081 4 101 101 CD cord-006870-f5w6fw6q 4081 5 patients patient NNS cord-006870-f5w6fw6q 4081 6 admitted admit VBN cord-006870-f5w6fw6q 4081 7 to to IN cord-006870-f5w6fw6q 4081 8 the the DT cord-006870-f5w6fw6q 4081 9 PICU PICU NNP cord-006870-f5w6fw6q 4081 10 with with IN cord-006870-f5w6fw6q 4081 11 an an DT cord-006870-f5w6fw6q 4081 12 acute acute JJ cord-006870-f5w6fw6q 4081 13 head head NN cord-006870-f5w6fw6q 4081 14 injury injury NN cord-006870-f5w6fw6q 4081 15 between between IN cord-006870-f5w6fw6q 4081 16 September September NNP cord-006870-f5w6fw6q 4081 17 2010 2010 CD cord-006870-f5w6fw6q 4081 18 and and CC cord-006870-f5w6fw6q 4081 19 May May NNP cord-006870-f5w6fw6q 4081 20 2016 2016 CD cord-006870-f5w6fw6q 4081 21 who who WP cord-006870-f5w6fw6q 4081 22 underwent undergo VBD cord-006870-f5w6fw6q 4081 23 head head NN cord-006870-f5w6fw6q 4081 24 MRI MRI NNP cord-006870-f5w6fw6q 4081 25 within within IN cord-006870-f5w6fw6q 4081 26 the the DT cord-006870-f5w6fw6q 4081 27 first first JJ cord-006870-f5w6fw6q 4081 28 96hrs 96hrs NN cord-006870-f5w6fw6q 4081 29 . . . cord-006870-f5w6fw6q 4082 1 We -PRON- PRP cord-006870-f5w6fw6q 4082 2 compared compare VBD cord-006870-f5w6fw6q 4082 3 MRI MRI NNP cord-006870-f5w6fw6q 4082 4 with with IN cord-006870-f5w6fw6q 4082 5 CT CT NNP cord-006870-f5w6fw6q 4082 6 findings finding NNS cord-006870-f5w6fw6q 4082 7 , , , cord-006870-f5w6fw6q 4082 8 using use VBG cord-006870-f5w6fw6q 4082 9 the the DT cord-006870-f5w6fw6q 4082 10 NIH NIH NNP cord-006870-f5w6fw6q 4082 11 Common Common NNP cord-006870-f5w6fw6q 4082 12 Data Data NNP cord-006870-f5w6fw6q 4082 13 Elements Elements NNP cord-006870-f5w6fw6q 4082 14 definitions definition NNS cord-006870-f5w6fw6q 4082 15 of of IN cord-006870-f5w6fw6q 4082 16 injury injury NN cord-006870-f5w6fw6q 4082 17 type type NN cord-006870-f5w6fw6q 4082 18 . . . cord-006870-f5w6fw6q 4083 1 We -PRON- PRP cord-006870-f5w6fw6q 4083 2 determined determine VBD cord-006870-f5w6fw6q 4083 3 by by IN cord-006870-f5w6fw6q 4083 4 chart chart NN cord-006870-f5w6fw6q 4083 5 review review VB cord-006870-f5w6fw6q 4083 6 the the DT cord-006870-f5w6fw6q 4083 7 indication indication NN cord-006870-f5w6fw6q 4083 8 for for IN cord-006870-f5w6fw6q 4083 9 MRI MRI NNP cord-006870-f5w6fw6q 4083 10 and and CC cord-006870-f5w6fw6q 4083 11 if if IN cord-006870-f5w6fw6q 4083 12 there there EX cord-006870-f5w6fw6q 4083 13 was be VBD cord-006870-f5w6fw6q 4083 14 documentation documentation NN cord-006870-f5w6fw6q 4083 15 that that IN cord-006870-f5w6fw6q 4083 16 MRI MRI NNP cord-006870-f5w6fw6q 4083 17 led lead VBD cord-006870-f5w6fw6q 4083 18 to to IN cord-006870-f5w6fw6q 4083 19 a a DT cord-006870-f5w6fw6q 4083 20 change change NN cord-006870-f5w6fw6q 4083 21 in in IN cord-006870-f5w6fw6q 4083 22 management management NN cord-006870-f5w6fw6q 4083 23 , , , cord-006870-f5w6fw6q 4083 24 defined define VBN cord-006870-f5w6fw6q 4083 25 as as IN cord-006870-f5w6fw6q 4083 26 either either CC cord-006870-f5w6fw6q 4083 27 an an DT cord-006870-f5w6fw6q 4083 28 escalation escalation NN cord-006870-f5w6fw6q 4083 29 or or CC cord-006870-f5w6fw6q 4083 30 a a DT cord-006870-f5w6fw6q 4083 31 de de NN cord-006870-f5w6fw6q 4083 32 - - NN cord-006870-f5w6fw6q 4083 33 escalation escalation NN cord-006870-f5w6fw6q 4083 34 of of IN cord-006870-f5w6fw6q 4083 35 care care NN cord-006870-f5w6fw6q 4083 36 . . . cord-006870-f5w6fw6q 4084 1 Seven seven CD cord-006870-f5w6fw6q 4084 2 patients patient NNS cord-006870-f5w6fw6q 4084 3 had have VBD cord-006870-f5w6fw6q 4084 4 MRI MRI NNP cord-006870-f5w6fw6q 4084 5 only only RB cord-006870-f5w6fw6q 4084 6 , , , cord-006870-f5w6fw6q 4084 7 and and CC cord-006870-f5w6fw6q 4084 8 MRI MRI NNP cord-006870-f5w6fw6q 4084 9 identified identify VBD cord-006870-f5w6fw6q 4084 10 additional additional JJ cord-006870-f5w6fw6q 4084 11 lesions lesion NNS cord-006870-f5w6fw6q 4084 12 in in IN cord-006870-f5w6fw6q 4084 13 60 60 CD cord-006870-f5w6fw6q 4084 14 of of IN cord-006870-f5w6fw6q 4084 15 the the DT cord-006870-f5w6fw6q 4084 16 94 94 CD cord-006870-f5w6fw6q 4084 17 patients patient NNS cord-006870-f5w6fw6q 4084 18 who who WP cord-006870-f5w6fw6q 4084 19 had have VBD cord-006870-f5w6fw6q 4084 20 first first RB cord-006870-f5w6fw6q 4084 21 undergone undergo VBN cord-006870-f5w6fw6q 4084 22 head head NN cord-006870-f5w6fw6q 4084 23 CT CT NNP cord-006870-f5w6fw6q 4084 24 . . . cord-006870-f5w6fw6q 4085 1 Of of IN cord-006870-f5w6fw6q 4085 2 these these DT cord-006870-f5w6fw6q 4085 3 , , , cord-006870-f5w6fw6q 4085 4 49 49 CD cord-006870-f5w6fw6q 4085 5 patients patient NNS cord-006870-f5w6fw6q 4085 6 had have VBD cord-006870-f5w6fw6q 4085 7 new new JJ cord-006870-f5w6fw6q 4085 8 intra intra JJ cord-006870-f5w6fw6q 4085 9 - - JJ cord-006870-f5w6fw6q 4085 10 parenchymal parenchymal JJ cord-006870-f5w6fw6q 4085 11 lesions lesion NNS cord-006870-f5w6fw6q 4085 12 , , , cord-006870-f5w6fw6q 4085 13 22 22 CD cord-006870-f5w6fw6q 4085 14 had have VBD cord-006870-f5w6fw6q 4085 15 new new JJ cord-006870-f5w6fw6q 4085 16 extra extra JJ cord-006870-f5w6fw6q 4085 17 - - JJ cord-006870-f5w6fw6q 4085 18 axial axial JJ cord-006870-f5w6fw6q 4085 19 lesions lesion NNS cord-006870-f5w6fw6q 4085 20 , , , cord-006870-f5w6fw6q 4085 21 and and CC cord-006870-f5w6fw6q 4085 22 11 11 CD cord-006870-f5w6fw6q 4085 23 had have VBD cord-006870-f5w6fw6q 4085 24 both both CC cord-006870-f5w6fw6q 4085 25 a a DT cord-006870-f5w6fw6q 4085 26 new new JJ cord-006870-f5w6fw6q 4085 27 intra intra JJ cord-006870-f5w6fw6q 4085 28 - - JJ cord-006870-f5w6fw6q 4085 29 parenchymal parenchymal JJ cord-006870-f5w6fw6q 4085 30 and and CC cord-006870-f5w6fw6q 4085 31 a a DT cord-006870-f5w6fw6q 4085 32 new new JJ cord-006870-f5w6fw6q 4085 33 extra extra JJ cord-006870-f5w6fw6q 4085 34 - - HYPH cord-006870-f5w6fw6q 4085 35 parenchymal parenchymal JJ cord-006870-f5w6fw6q 4085 36 lesion lesion NN cord-006870-f5w6fw6q 4085 37 identified identify VBN cord-006870-f5w6fw6q 4085 38 . . . cord-006870-f5w6fw6q 4086 1 The the DT cord-006870-f5w6fw6q 4086 2 most most RBS cord-006870-f5w6fw6q 4086 3 frequent frequent JJ cord-006870-f5w6fw6q 4086 4 new new JJ cord-006870-f5w6fw6q 4086 5 lesions lesion NNS cord-006870-f5w6fw6q 4086 6 were be VBD cord-006870-f5w6fw6q 4086 7 contusions contusion NNS cord-006870-f5w6fw6q 4086 8 and and CC cord-006870-f5w6fw6q 4086 9 traumatic traumatic JJ cord-006870-f5w6fw6q 4086 10 or or CC cord-006870-f5w6fw6q 4086 11 diffuse diffuse VB cord-006870-f5w6fw6q 4086 12 axonal axonal JJ cord-006870-f5w6fw6q 4086 13 injury injury NN cord-006870-f5w6fw6q 4086 14 . . . cord-006870-f5w6fw6q 4087 1 Acute acute JJ cord-006870-f5w6fw6q 4087 2 management management NN cord-006870-f5w6fw6q 4087 3 was be VBD cord-006870-f5w6fw6q 4087 4 influenced influence VBN cord-006870-f5w6fw6q 4087 5 by by IN cord-006870-f5w6fw6q 4087 6 MRI MRI NNP cord-006870-f5w6fw6q 4087 7 in in IN cord-006870-f5w6fw6q 4087 8 a a DT cord-006870-f5w6fw6q 4087 9 majority majority NN cord-006870-f5w6fw6q 4087 10 of of IN cord-006870-f5w6fw6q 4087 11 patients patient NNS cord-006870-f5w6fw6q 4087 12 , , , cord-006870-f5w6fw6q 4087 13 leading lead VBG cord-006870-f5w6fw6q 4087 14 to to IN cord-006870-f5w6fw6q 4087 15 an an DT cord-006870-f5w6fw6q 4087 16 escalation escalation NN cord-006870-f5w6fw6q 4087 17 of of IN cord-006870-f5w6fw6q 4087 18 medical medical JJ cord-006870-f5w6fw6q 4087 19 or or CC cord-006870-f5w6fw6q 4087 20 surgical surgical JJ cord-006870-f5w6fw6q 4087 21 management management NN cord-006870-f5w6fw6q 4087 22 in in IN cord-006870-f5w6fw6q 4087 23 nearly nearly RB cord-006870-f5w6fw6q 4087 24 one one CD cord-006870-f5w6fw6q 4087 25 third third NN cord-006870-f5w6fw6q 4087 26 and and CC cord-006870-f5w6fw6q 4087 27 a a DT cord-006870-f5w6fw6q 4087 28 de de NN cord-006870-f5w6fw6q 4087 29 - - NN cord-006870-f5w6fw6q 4087 30 escalation escalation NN cord-006870-f5w6fw6q 4087 31 of of IN cord-006870-f5w6fw6q 4087 32 care care NN cord-006870-f5w6fw6q 4087 33 in in IN cord-006870-f5w6fw6q 4087 34 half half NN cord-006870-f5w6fw6q 4087 35 . . . cord-006870-f5w6fw6q 4088 1 Early early JJ cord-006870-f5w6fw6q 4088 2 MRI MRI NNP cord-006870-f5w6fw6q 4088 3 may may MD cord-006870-f5w6fw6q 4088 4 have have VB cord-006870-f5w6fw6q 4088 5 a a DT cord-006870-f5w6fw6q 4088 6 beneficial beneficial JJ cord-006870-f5w6fw6q 4088 7 role role NN cord-006870-f5w6fw6q 4088 8 in in IN cord-006870-f5w6fw6q 4088 9 the the DT cord-006870-f5w6fw6q 4088 10 acute acute JJ cord-006870-f5w6fw6q 4088 11 management management NN cord-006870-f5w6fw6q 4088 12 of of IN cord-006870-f5w6fw6q 4088 13 pediatric pediatric JJ cord-006870-f5w6fw6q 4088 14 traumatic traumatic JJ cord-006870-f5w6fw6q 4088 15 brain brain NN cord-006870-f5w6fw6q 4088 16 injury injury NN cord-006870-f5w6fw6q 4088 17 . . . cord-006870-f5w6fw6q 4089 1 MRI MRI NNP cord-006870-f5w6fw6q 4089 2 frequently frequently RB cord-006870-f5w6fw6q 4089 3 identified identify VBD cord-006870-f5w6fw6q 4089 4 clinically clinically RB cord-006870-f5w6fw6q 4089 5 important important JJ cord-006870-f5w6fw6q 4089 6 lesions lesion NNS cord-006870-f5w6fw6q 4089 7 not not RB cord-006870-f5w6fw6q 4089 8 appreciated appreciate VBN cord-006870-f5w6fw6q 4089 9 on on IN cord-006870-f5w6fw6q 4089 10 CT CT NNP cord-006870-f5w6fw6q 4089 11 , , , cord-006870-f5w6fw6q 4089 12 and and CC cord-006870-f5w6fw6q 4089 13 findings finding NNS cord-006870-f5w6fw6q 4089 14 influenced influence VBD cord-006870-f5w6fw6q 4089 15 management management NN cord-006870-f5w6fw6q 4089 16 decisions decision NNS cord-006870-f5w6fw6q 4089 17 . . . cord-006870-f5w6fw6q 4090 1 Future future JJ cord-006870-f5w6fw6q 4090 2 studies study NNS cord-006870-f5w6fw6q 4090 3 will will MD cord-006870-f5w6fw6q 4090 4 assess assess VB cord-006870-f5w6fw6q 4090 5 whether whether IN cord-006870-f5w6fw6q 4090 6 early early JJ cord-006870-f5w6fw6q 4090 7 MRI MRI NNP cord-006870-f5w6fw6q 4090 8 improves improve VBZ cord-006870-f5w6fw6q 4090 9 patient patient NN cord-006870-f5w6fw6q 4090 10 outcomes outcome NNS cord-006870-f5w6fw6q 4090 11 or or CC cord-006870-f5w6fw6q 4090 12 provides provide VBZ cord-006870-f5w6fw6q 4090 13 cost cost NN cord-006870-f5w6fw6q 4090 14 / / SYM cord-006870-f5w6fw6q 4090 15 benefit benefit NN cord-006870-f5w6fw6q 4090 16 by by IN cord-006870-f5w6fw6q 4090 17 reducing reduce VBG cord-006870-f5w6fw6q 4090 18 length length NN cord-006870-f5w6fw6q 4090 19 of of IN cord-006870-f5w6fw6q 4090 20 stay stay NN cord-006870-f5w6fw6q 4090 21 . . . cord-006870-f5w6fw6q 4091 1 While while IN cord-006870-f5w6fw6q 4091 2 adverse adverse JJ cord-006870-f5w6fw6q 4091 3 outcomes outcome NNS cord-006870-f5w6fw6q 4091 4 of of IN cord-006870-f5w6fw6q 4091 5 decompressive decompressive JJ cord-006870-f5w6fw6q 4091 6 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 4091 7 ( ( -LRB- cord-006870-f5w6fw6q 4091 8 DH DH NNP cord-006870-f5w6fw6q 4091 9 ) ) -RRB- cord-006870-f5w6fw6q 4091 10 including include VBG cord-006870-f5w6fw6q 4091 11 infection infection NN cord-006870-f5w6fw6q 4091 12 , , , cord-006870-f5w6fw6q 4091 13 disturbances disturbance NNS cord-006870-f5w6fw6q 4091 14 of of IN cord-006870-f5w6fw6q 4091 15 the the DT cord-006870-f5w6fw6q 4091 16 CSF CSF NNP cord-006870-f5w6fw6q 4091 17 compartment compartment NN cord-006870-f5w6fw6q 4091 18 , , , cord-006870-f5w6fw6q 4091 19 and and CC cord-006870-f5w6fw6q 4091 20 sunken sunken JJ cord-006870-f5w6fw6q 4091 21 flap flap NN cord-006870-f5w6fw6q 4091 22 syndrome syndrome NN cord-006870-f5w6fw6q 4091 23 are be VBP cord-006870-f5w6fw6q 4091 24 well well RB cord-006870-f5w6fw6q 4091 25 documented document VBN cord-006870-f5w6fw6q 4091 26 , , , cord-006870-f5w6fw6q 4091 27 there there EX cord-006870-f5w6fw6q 4091 28 is be VBZ cord-006870-f5w6fw6q 4091 29 a a DT cord-006870-f5w6fw6q 4091 30 dearth dearth NN cord-006870-f5w6fw6q 4091 31 of of IN cord-006870-f5w6fw6q 4091 32 literature literature NN cord-006870-f5w6fw6q 4091 33 assessing assess VBG cord-006870-f5w6fw6q 4091 34 outcomes outcome NNS cord-006870-f5w6fw6q 4091 35 related relate VBN cord-006870-f5w6fw6q 4091 36 to to IN cord-006870-f5w6fw6q 4091 37 the the DT cord-006870-f5w6fw6q 4091 38 timing timing NN cord-006870-f5w6fw6q 4091 39 of of IN cord-006870-f5w6fw6q 4091 40 cranioplasty cranioplasty NNP cord-006870-f5w6fw6q 4091 41 . . . cord-006870-f5w6fw6q 4092 1 While while IN cord-006870-f5w6fw6q 4092 2 adverse adverse JJ cord-006870-f5w6fw6q 4092 3 outcomes outcome NNS cord-006870-f5w6fw6q 4092 4 of of IN cord-006870-f5w6fw6q 4092 5 decompressive decompressive JJ cord-006870-f5w6fw6q 4092 6 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 4092 7 ( ( -LRB- cord-006870-f5w6fw6q 4092 8 DH DH NNP cord-006870-f5w6fw6q 4092 9 ) ) -RRB- cord-006870-f5w6fw6q 4092 10 including include VBG cord-006870-f5w6fw6q 4092 11 infection infection NN cord-006870-f5w6fw6q 4092 12 , , , cord-006870-f5w6fw6q 4092 13 disturbances disturbance NNS cord-006870-f5w6fw6q 4092 14 of of IN cord-006870-f5w6fw6q 4092 15 the the DT cord-006870-f5w6fw6q 4092 16 CSF CSF NNP cord-006870-f5w6fw6q 4092 17 compartment compartment NN cord-006870-f5w6fw6q 4092 18 , , , cord-006870-f5w6fw6q 4092 19 and and CC cord-006870-f5w6fw6q 4092 20 sunken sunken JJ cord-006870-f5w6fw6q 4092 21 flap flap NN cord-006870-f5w6fw6q 4092 22 syndrome syndrome NN cord-006870-f5w6fw6q 4092 23 are be VBP cord-006870-f5w6fw6q 4092 24 well well RB cord-006870-f5w6fw6q 4092 25 documented document VBN cord-006870-f5w6fw6q 4092 26 , , , cord-006870-f5w6fw6q 4092 27 there there EX cord-006870-f5w6fw6q 4092 28 is be VBZ cord-006870-f5w6fw6q 4092 29 a a DT cord-006870-f5w6fw6q 4092 30 dearth dearth NN cord-006870-f5w6fw6q 4092 31 of of IN cord-006870-f5w6fw6q 4092 32 literature literature NN cord-006870-f5w6fw6q 4092 33 assessing assess VBG cord-006870-f5w6fw6q 4092 34 outcomes outcome NNS cord-006870-f5w6fw6q 4092 35 related relate VBN cord-006870-f5w6fw6q 4092 36 to to IN cord-006870-f5w6fw6q 4092 37 the the DT cord-006870-f5w6fw6q 4092 38 timing timing NN cord-006870-f5w6fw6q 4092 39 of of IN cord-006870-f5w6fw6q 4092 40 cranioplasty cranioplasty NNP cord-006870-f5w6fw6q 4092 41 . . . cord-006870-f5w6fw6q 4093 1 We -PRON- PRP cord-006870-f5w6fw6q 4093 2 identified identify VBD cord-006870-f5w6fw6q 4093 3 143 143 CD cord-006870-f5w6fw6q 4093 4 patients patient NNS cord-006870-f5w6fw6q 4093 5 who who WP cord-006870-f5w6fw6q 4093 6 received receive VBD cord-006870-f5w6fw6q 4093 7 DH DH NNP cord-006870-f5w6fw6q 4093 8 , , , cord-006870-f5w6fw6q 4093 9 60 60 CD cord-006870-f5w6fw6q 4093 10 of of IN cord-006870-f5w6fw6q 4093 11 whom whom WP cord-006870-f5w6fw6q 4093 12 underwent undergo VBD cord-006870-f5w6fw6q 4093 13 reconstructive reconstructive JJ cord-006870-f5w6fw6q 4093 14 cranioplasty cranioplasty NN cord-006870-f5w6fw6q 4093 15 at at IN cord-006870-f5w6fw6q 4093 16 our -PRON- PRP$ cord-006870-f5w6fw6q 4093 17 institution institution NN cord-006870-f5w6fw6q 4093 18 . . . cord-006870-f5w6fw6q 4094 1 The the DT cord-006870-f5w6fw6q 4094 2 post post JJ cord-006870-f5w6fw6q 4094 3 - - JJ cord-006870-f5w6fw6q 4094 4 cranioplasty cranioplasty JJ cord-006870-f5w6fw6q 4094 5 complication complication NN cord-006870-f5w6fw6q 4094 6 rate rate NN cord-006870-f5w6fw6q 4094 7 was be VBD cord-006870-f5w6fw6q 4094 8 20 20 CD cord-006870-f5w6fw6q 4094 9 % % NN cord-006870-f5w6fw6q 4094 10 , , , cord-006870-f5w6fw6q 4094 11 which which WDT cord-006870-f5w6fw6q 4094 12 was be VBD cord-006870-f5w6fw6q 4094 13 due due JJ cord-006870-f5w6fw6q 4094 14 in in IN cord-006870-f5w6fw6q 4094 15 part part NN cord-006870-f5w6fw6q 4094 16 to to IN cord-006870-f5w6fw6q 4094 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4094 18 , , , cord-006870-f5w6fw6q 4094 19 infectious infectious JJ cord-006870-f5w6fw6q 4094 20 complications complication NNS cord-006870-f5w6fw6q 4094 21 , , , cord-006870-f5w6fw6q 4094 22 or or CC cord-006870-f5w6fw6q 4094 23 CSF CSF NNP cord-006870-f5w6fw6q 4094 24 compartment compartment NN cord-006870-f5w6fw6q 4094 25 disturbances disturbance NNS cord-006870-f5w6fw6q 4094 26 . . . cord-006870-f5w6fw6q 4095 1 Patients patient NNS cord-006870-f5w6fw6q 4095 2 receiving receive VBG cord-006870-f5w6fw6q 4095 3 early early JJ cord-006870-f5w6fw6q 4095 4 cranioplasty cranioplasty NNP cord-006870-f5w6fw6q 4095 5 developed develop VBD cord-006870-f5w6fw6q 4095 6 an an DT cord-006870-f5w6fw6q 4095 7 increased increase VBN cord-006870-f5w6fw6q 4095 8 rate rate NN cord-006870-f5w6fw6q 4095 9 of of IN cord-006870-f5w6fw6q 4095 10 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 4095 11 complication complication NN cord-006870-f5w6fw6q 4095 12 ( ( -LRB- cord-006870-f5w6fw6q 4095 13 19 19 CD cord-006870-f5w6fw6q 4095 14 % % NN cord-006870-f5w6fw6q 4095 15 vs vs IN cord-006870-f5w6fw6q 4095 16 0 0 CD cord-006870-f5w6fw6q 4095 17 % % NN cord-006870-f5w6fw6q 4095 18 ; ; : cord-006870-f5w6fw6q 4095 19 p p NN cord-006870-f5w6fw6q 4095 20 = = SYM cord-006870-f5w6fw6q 4095 21 0.01 0.01 CD cord-006870-f5w6fw6q 4095 22 ) ) -RRB- cord-006870-f5w6fw6q 4095 23 , , , cord-006870-f5w6fw6q 4095 24 increased increase VBN cord-006870-f5w6fw6q 4095 25 median median JJ cord-006870-f5w6fw6q 4095 26 hospital hospital NN cord-006870-f5w6fw6q 4095 27 length length NN cord-006870-f5w6fw6q 4095 28 of of IN cord-006870-f5w6fw6q 4095 29 stay stay NN cord-006870-f5w6fw6q 4095 30 ( ( -LRB- cord-006870-f5w6fw6q 4095 31 LOS LOS NNP cord-006870-f5w6fw6q 4095 32 ) ) -RRB- cord-006870-f5w6fw6q 4095 33 ( ( -LRB- cord-006870-f5w6fw6q 4095 34 10 10 CD cord-006870-f5w6fw6q 4095 35 vs vs IN cord-006870-f5w6fw6q 4095 36 4 4 CD cord-006870-f5w6fw6q 4095 37 days day NNS cord-006870-f5w6fw6q 4095 38 ; ; : cord-006870-f5w6fw6q 4095 39 p p NN cord-006870-f5w6fw6q 4095 40 = = SYM cord-006870-f5w6fw6q 4095 41 0.002 0.002 CD cord-006870-f5w6fw6q 4095 42 ) ) -RRB- cord-006870-f5w6fw6q 4095 43 and and CC cord-006870-f5w6fw6q 4095 44 increased increase VBD cord-006870-f5w6fw6q 4095 45 median median JJ cord-006870-f5w6fw6q 4095 46 ICU ICU NNP cord-006870-f5w6fw6q 4095 47 LOS LOS NNP cord-006870-f5w6fw6q 4095 48 ( ( -LRB- cord-006870-f5w6fw6q 4095 49 3 3 CD cord-006870-f5w6fw6q 4095 50 vs vs IN cord-006870-f5w6fw6q 4095 51 1 1 CD cord-006870-f5w6fw6q 4095 52 days day NNS cord-006870-f5w6fw6q 4095 53 ; ; : cord-006870-f5w6fw6q 4095 54 p p NN cord-006870-f5w6fw6q 4095 55 = = SYM cord-006870-f5w6fw6q 4095 56 0.01 0.01 CD cord-006870-f5w6fw6q 4095 57 ) ) -RRB- cord-006870-f5w6fw6q 4095 58 . . . cord-006870-f5w6fw6q 4096 1 Of of IN cord-006870-f5w6fw6q 4096 2 the the DT cord-006870-f5w6fw6q 4096 3 patients patient NNS cord-006870-f5w6fw6q 4096 4 who who WP cord-006870-f5w6fw6q 4096 5 received receive VBD cord-006870-f5w6fw6q 4096 6 DH dh NN cord-006870-f5w6fw6q 4096 7 surgery surgery NN cord-006870-f5w6fw6q 4096 8 related relate VBN cord-006870-f5w6fw6q 4096 9 to to IN cord-006870-f5w6fw6q 4096 10 malignant malignant JJ cord-006870-f5w6fw6q 4096 11 cerebral cerebral JJ cord-006870-f5w6fw6q 4096 12 edema edema NN cord-006870-f5w6fw6q 4096 13 from from IN cord-006870-f5w6fw6q 4096 14 an an DT cord-006870-f5w6fw6q 4096 15 acute acute JJ cord-006870-f5w6fw6q 4096 16 ischemic ischemic JJ cord-006870-f5w6fw6q 4096 17 stroke stroke NN cord-006870-f5w6fw6q 4096 18 , , , cord-006870-f5w6fw6q 4096 19 total total JJ cord-006870-f5w6fw6q 4096 20 complication complication NN cord-006870-f5w6fw6q 4096 21 rates rate NNS cord-006870-f5w6fw6q 4096 22 trended trend VBD cord-006870-f5w6fw6q 4096 23 down down RP cord-006870-f5w6fw6q 4096 24 for for IN cord-006870-f5w6fw6q 4096 25 early early RB cord-006870-f5w6fw6q 4096 26 compared compare VBN cord-006870-f5w6fw6q 4096 27 to to IN cord-006870-f5w6fw6q 4096 28 late late JJ cord-006870-f5w6fw6q 4096 29 cranioplasty cranioplasty NN cord-006870-f5w6fw6q 4096 30 surgery surgery NN cord-006870-f5w6fw6q 4096 31 ( ( -LRB- cord-006870-f5w6fw6q 4096 32 8 8 CD cord-006870-f5w6fw6q 4096 33 % % NN cord-006870-f5w6fw6q 4096 34 vs vs IN cord-006870-f5w6fw6q 4096 35 18 18 CD cord-006870-f5w6fw6q 4096 36 % % NN cord-006870-f5w6fw6q 4096 37 ; ; : cord-006870-f5w6fw6q 4096 38 p p NN cord-006870-f5w6fw6q 4096 39 = = SYM cord-006870-f5w6fw6q 4096 40 0.68 0.68 CD cord-006870-f5w6fw6q 4096 41 ) ) -RRB- cord-006870-f5w6fw6q 4096 42 . . . cord-006870-f5w6fw6q 4097 1 Patients patient NNS cord-006870-f5w6fw6q 4097 2 receiving receive VBG cord-006870-f5w6fw6q 4097 3 DH dh NN cord-006870-f5w6fw6q 4097 4 surgery surgery NN cord-006870-f5w6fw6q 4097 5 for for IN cord-006870-f5w6fw6q 4097 6 any any DT cord-006870-f5w6fw6q 4097 7 cause cause NN cord-006870-f5w6fw6q 4097 8 who who WP cord-006870-f5w6fw6q 4097 9 underwent undergo VBD cord-006870-f5w6fw6q 4097 10 early early JJ cord-006870-f5w6fw6q 4097 11 reconstructive reconstructive JJ cord-006870-f5w6fw6q 4097 12 cranioplasty cranioplasty NN cord-006870-f5w6fw6q 4097 13 , , , cord-006870-f5w6fw6q 4097 14 experienced experience VBD cord-006870-f5w6fw6q 4097 15 higher high JJR cord-006870-f5w6fw6q 4097 16 rates rate NNS cord-006870-f5w6fw6q 4097 17 of of IN cord-006870-f5w6fw6q 4097 18 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 4097 19 complications complication NNS cord-006870-f5w6fw6q 4097 20 and and CC cord-006870-f5w6fw6q 4097 21 increased increase VBN cord-006870-f5w6fw6q 4097 22 hospital hospital NN cord-006870-f5w6fw6q 4097 23 and and CC cord-006870-f5w6fw6q 4097 24 ICU ICU NNP cord-006870-f5w6fw6q 4097 25 LOS LOS NNP cord-006870-f5w6fw6q 4097 26 . . . cord-006870-f5w6fw6q 4098 1 However however RB cord-006870-f5w6fw6q 4098 2 , , , cord-006870-f5w6fw6q 4098 3 among among IN cord-006870-f5w6fw6q 4098 4 those those DT cord-006870-f5w6fw6q 4098 5 patients patient NNS cord-006870-f5w6fw6q 4098 6 receiving receive VBG cord-006870-f5w6fw6q 4098 7 DH dh NN cord-006870-f5w6fw6q 4098 8 surgery surgery NN cord-006870-f5w6fw6q 4098 9 for for IN cord-006870-f5w6fw6q 4098 10 the the DT cord-006870-f5w6fw6q 4098 11 specific specific JJ cord-006870-f5w6fw6q 4098 12 indication indication NN cord-006870-f5w6fw6q 4098 13 of of IN cord-006870-f5w6fw6q 4098 14 malignant malignant JJ cord-006870-f5w6fw6q 4098 15 cerebral cerebral JJ cord-006870-f5w6fw6q 4098 16 edema edema NN cord-006870-f5w6fw6q 4098 17 from from IN cord-006870-f5w6fw6q 4098 18 acute acute JJ cord-006870-f5w6fw6q 4098 19 ischemic ischemic JJ cord-006870-f5w6fw6q 4098 20 stroke stroke NN cord-006870-f5w6fw6q 4098 21 , , , cord-006870-f5w6fw6q 4098 22 significant significant JJ cord-006870-f5w6fw6q 4098 23 differences difference NNS cord-006870-f5w6fw6q 4098 24 did do VBD cord-006870-f5w6fw6q 4098 25 not not RB cord-006870-f5w6fw6q 4098 26 exist exist VB cord-006870-f5w6fw6q 4098 27 between between IN cord-006870-f5w6fw6q 4098 28 the the DT cord-006870-f5w6fw6q 4098 29 early early JJ cord-006870-f5w6fw6q 4098 30 and and CC cord-006870-f5w6fw6q 4098 31 late late JJ cord-006870-f5w6fw6q 4098 32 cranioplasty cranioplasty NN cord-006870-f5w6fw6q 4098 33 groups group NNS cord-006870-f5w6fw6q 4098 34 . . . cord-006870-f5w6fw6q 4099 1 The the DT cord-006870-f5w6fw6q 4099 2 total total JJ cord-006870-f5w6fw6q 4099 3 complication complication NN cord-006870-f5w6fw6q 4099 4 rates rate NNS cord-006870-f5w6fw6q 4099 5 in in IN cord-006870-f5w6fw6q 4099 6 these these DT cord-006870-f5w6fw6q 4099 7 patients patient NNS cord-006870-f5w6fw6q 4099 8 trended trend VBD cord-006870-f5w6fw6q 4099 9 lower lower RBR cord-006870-f5w6fw6q 4099 10 in in IN cord-006870-f5w6fw6q 4099 11 the the DT cord-006870-f5w6fw6q 4099 12 early early JJ cord-006870-f5w6fw6q 4099 13 group group NN cord-006870-f5w6fw6q 4099 14 . . . cord-006870-f5w6fw6q 4100 1 Another another DT cord-006870-f5w6fw6q 4100 2 important important JJ cord-006870-f5w6fw6q 4100 3 and and CC cord-006870-f5w6fw6q 4100 4 mainly mainly RB cord-006870-f5w6fw6q 4100 5 unpublished unpublished JJ cord-006870-f5w6fw6q 4100 6 finding finding NN cord-006870-f5w6fw6q 4100 7 is be VBZ cord-006870-f5w6fw6q 4100 8 that that IN cord-006870-f5w6fw6q 4100 9 a a DT cord-006870-f5w6fw6q 4100 10 majority majority NN cord-006870-f5w6fw6q 4100 11 of of IN cord-006870-f5w6fw6q 4100 12 DH DH NNP cord-006870-f5w6fw6q 4100 13 patients patient NNS cord-006870-f5w6fw6q 4100 14 are be VBP cord-006870-f5w6fw6q 4100 15 lost lose VBN cord-006870-f5w6fw6q 4100 16 to to IN cord-006870-f5w6fw6q 4100 17 surgical surgical JJ cord-006870-f5w6fw6q 4100 18 follow follow NN cord-006870-f5w6fw6q 4100 19 up up RP cord-006870-f5w6fw6q 4100 20 and and CC cord-006870-f5w6fw6q 4100 21 may may MD cord-006870-f5w6fw6q 4100 22 therefore therefore RB cord-006870-f5w6fw6q 4100 23 impact impact VB cord-006870-f5w6fw6q 4100 24 the the DT cord-006870-f5w6fw6q 4100 25 complication complication NN cord-006870-f5w6fw6q 4100 26 rate rate NN cord-006870-f5w6fw6q 4100 27 of of IN cord-006870-f5w6fw6q 4100 28 this this DT cord-006870-f5w6fw6q 4100 29 not not RB cord-006870-f5w6fw6q 4100 30 so so RB cord-006870-f5w6fw6q 4100 31 benign benign JJ cord-006870-f5w6fw6q 4100 32 surgery surgery NN cord-006870-f5w6fw6q 4100 33 . . . cord-006870-f5w6fw6q 4101 1 Postoperative postoperative JJ cord-006870-f5w6fw6q 4101 2 antibiotics antibiotic NNS cord-006870-f5w6fw6q 4101 3 ( ( -LRB- cord-006870-f5w6fw6q 4101 4 PA PA NNP cord-006870-f5w6fw6q 4101 5 ) ) -RRB- cord-006870-f5w6fw6q 4101 6 are be VBP cord-006870-f5w6fw6q 4101 7 often often RB cord-006870-f5w6fw6q 4101 8 administered administer VBN cord-006870-f5w6fw6q 4101 9 to to IN cord-006870-f5w6fw6q 4101 10 patients patient NNS cord-006870-f5w6fw6q 4101 11 after after IN cord-006870-f5w6fw6q 4101 12 instrumented instrument VBN cord-006870-f5w6fw6q 4101 13 spinal spinal JJ cord-006870-f5w6fw6q 4101 14 surgery surgery NN cord-006870-f5w6fw6q 4101 15 until until IN cord-006870-f5w6fw6q 4101 16 all all DT cord-006870-f5w6fw6q 4101 17 drains drain NNS cord-006870-f5w6fw6q 4101 18 are be VBP cord-006870-f5w6fw6q 4101 19 removed remove VBN cord-006870-f5w6fw6q 4101 20 to to TO cord-006870-f5w6fw6q 4101 21 prevent prevent VB cord-006870-f5w6fw6q 4101 22 surgical surgical JJ cord-006870-f5w6fw6q 4101 23 site site NN cord-006870-f5w6fw6q 4101 24 infections infection NNS cord-006870-f5w6fw6q 4101 25 ( ( -LRB- cord-006870-f5w6fw6q 4101 26 SSI SSI NNP cord-006870-f5w6fw6q 4101 27 ) ) -RRB- cord-006870-f5w6fw6q 4101 28 . . . cord-006870-f5w6fw6q 4102 1 This this DT cord-006870-f5w6fw6q 4102 2 practice practice NN cord-006870-f5w6fw6q 4102 3 is be VBZ cord-006870-f5w6fw6q 4102 4 discouraged discourage VBN cord-006870-f5w6fw6q 4102 5 by by IN cord-006870-f5w6fw6q 4102 6 numerous numerous JJ cord-006870-f5w6fw6q 4102 7 medical medical JJ cord-006870-f5w6fw6q 4102 8 society society NN cord-006870-f5w6fw6q 4102 9 guidelines guideline NNS cord-006870-f5w6fw6q 4102 10 , , , cord-006870-f5w6fw6q 4102 11 so so IN cord-006870-f5w6fw6q 4102 12 our -PRON- PRP$ cord-006870-f5w6fw6q 4102 13 institutional institutional JJ cord-006870-f5w6fw6q 4102 14 Neurosurgery Neurosurgery NNP cord-006870-f5w6fw6q 4102 15 Quality Quality NNP cord-006870-f5w6fw6q 4102 16 Improvement Improvement NNP cord-006870-f5w6fw6q 4102 17 Committee Committee NNP cord-006870-f5w6fw6q 4102 18 decided decide VBD cord-006870-f5w6fw6q 4102 19 to to TO cord-006870-f5w6fw6q 4102 20 discontinue discontinue VB cord-006870-f5w6fw6q 4102 21 use use NN cord-006870-f5w6fw6q 4102 22 of of IN cord-006870-f5w6fw6q 4102 23 PA PA NNP cord-006870-f5w6fw6q 4102 24 for for IN cord-006870-f5w6fw6q 4102 25 this this DT cord-006870-f5w6fw6q 4102 26 population population NN cord-006870-f5w6fw6q 4102 27 . . . cord-006870-f5w6fw6q 4103 1 We -PRON- PRP cord-006870-f5w6fw6q 4103 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 4103 3 reviewed review VBD cord-006870-f5w6fw6q 4103 4 data datum NNS cord-006870-f5w6fw6q 4103 5 for for IN cord-006870-f5w6fw6q 4103 6 patients patient NNS cord-006870-f5w6fw6q 4103 7 who who WP cord-006870-f5w6fw6q 4103 8 had have VBD cord-006870-f5w6fw6q 4103 9 instrumented instrument VBN cord-006870-f5w6fw6q 4103 10 spinal spinal JJ cord-006870-f5w6fw6q 4103 11 surgery surgery NN cord-006870-f5w6fw6q 4103 12 at at IN cord-006870-f5w6fw6q 4103 13 our -PRON- PRP$ cord-006870-f5w6fw6q 4103 14 institution institution NN cord-006870-f5w6fw6q 4103 15 for for IN cord-006870-f5w6fw6q 4103 16 seven seven CD cord-006870-f5w6fw6q 4103 17 months month NNS cord-006870-f5w6fw6q 4103 18 before before IN cord-006870-f5w6fw6q 4103 19 and and CC cord-006870-f5w6fw6q 4103 20 after after IN cord-006870-f5w6fw6q 4103 21 this this DT cord-006870-f5w6fw6q 4103 22 policy policy NN cord-006870-f5w6fw6q 4103 23 change change NN cord-006870-f5w6fw6q 4103 24 and and CC cord-006870-f5w6fw6q 4103 25 compared compare VBD cord-006870-f5w6fw6q 4103 26 the the DT cord-006870-f5w6fw6q 4103 27 frequency frequency NN cord-006870-f5w6fw6q 4103 28 of of IN cord-006870-f5w6fw6q 4103 29 SSI SSI NNP cord-006870-f5w6fw6q 4103 30 and and CC cord-006870-f5w6fw6q 4103 31 development development NN cord-006870-f5w6fw6q 4103 32 of of IN cord-006870-f5w6fw6q 4103 33 antibiotic antibiotic JJ cord-006870-f5w6fw6q 4103 34 related related JJ cord-006870-f5w6fw6q 4103 35 complications complication NNS cord-006870-f5w6fw6q 4103 36 in in IN cord-006870-f5w6fw6q 4103 37 patients patient NNS cord-006870-f5w6fw6q 4103 38 who who WP cord-006870-f5w6fw6q 4103 39 received receive VBD cord-006870-f5w6fw6q 4103 40 PA PA NNP cord-006870-f5w6fw6q 4103 41 to to IN cord-006870-f5w6fw6q 4103 42 those those DT cord-006870-f5w6fw6q 4103 43 who who WP cord-006870-f5w6fw6q 4103 44 did do VBD cord-006870-f5w6fw6q 4103 45 not not RB cord-006870-f5w6fw6q 4103 46 ( ( -LRB- cord-006870-f5w6fw6q 4103 47 non non NNP cord-006870-f5w6fw6q 4103 48 - - NNP cord-006870-f5w6fw6q 4103 49 PA PA NNP cord-006870-f5w6fw6q 4103 50 ) ) -RRB- cord-006870-f5w6fw6q 4103 51 . . . cord-006870-f5w6fw6q 4104 1 We -PRON- PRP cord-006870-f5w6fw6q 4104 2 identified identify VBD cord-006870-f5w6fw6q 4104 3 188 188 CD cord-006870-f5w6fw6q 4104 4 PA PA NNP cord-006870-f5w6fw6q 4104 5 patients patient NNS cord-006870-f5w6fw6q 4104 6 and and CC cord-006870-f5w6fw6q 4104 7 158 158 CD cord-006870-f5w6fw6q 4104 8 non non JJ cord-006870-f5w6fw6q 4104 9 - - JJ cord-006870-f5w6fw6q 4104 10 PA PA NNP cord-006870-f5w6fw6q 4104 11 patients patient NNS cord-006870-f5w6fw6q 4104 12 . . . cord-006870-f5w6fw6q 4105 1 Discontinuation discontinuation NN cord-006870-f5w6fw6q 4105 2 of of IN cord-006870-f5w6fw6q 4105 3 PA PA NNP cord-006870-f5w6fw6q 4105 4 did do VBD cord-006870-f5w6fw6q 4105 5 not not RB cord-006870-f5w6fw6q 4105 6 result result VB cord-006870-f5w6fw6q 4105 7 in in IN cord-006870-f5w6fw6q 4105 8 an an DT cord-006870-f5w6fw6q 4105 9 increase increase NN cord-006870-f5w6fw6q 4105 10 in in IN cord-006870-f5w6fw6q 4105 11 frequency frequency NN cord-006870-f5w6fw6q 4105 12 of of IN cord-006870-f5w6fw6q 4105 13 SSI SSI NNP cord-006870-f5w6fw6q 4105 14 ( ( -LRB- cord-006870-f5w6fw6q 4105 15 2 2 CD cord-006870-f5w6fw6q 4105 16 % % NN cord-006870-f5w6fw6q 4105 17 of of IN cord-006870-f5w6fw6q 4105 18 PA PA NNP cord-006870-f5w6fw6q 4105 19 patients patient NNS cord-006870-f5w6fw6q 4105 20 vs. vs. CC cord-006870-f5w6fw6q 4105 21 0.6 0.6 CD cord-006870-f5w6fw6q 4105 22 % % NN cord-006870-f5w6fw6q 4105 23 of of IN cord-006870-f5w6fw6q 4105 24 non non JJ cord-006870-f5w6fw6q 4105 25 - - JJ cord-006870-f5w6fw6q 4105 26 PA PA NNP cord-006870-f5w6fw6q 4105 27 patients patient NNS cord-006870-f5w6fw6q 4105 28 , , , cord-006870-f5w6fw6q 4105 29 p=0.4 p=0.4 NNP cord-006870-f5w6fw6q 4105 30 ) ) -RRB- cord-006870-f5w6fw6q 4105 31 . . . cord-006870-f5w6fw6q 4106 1 Growth growth NN cord-006870-f5w6fw6q 4106 2 of of IN cord-006870-f5w6fw6q 4106 3 resistant resistant JJ cord-006870-f5w6fw6q 4106 4 bacteria bacteria NNS cord-006870-f5w6fw6q 4106 5 was be VBD cord-006870-f5w6fw6q 4106 6 not not RB cord-006870-f5w6fw6q 4106 7 significantly significantly RB cord-006870-f5w6fw6q 4106 8 reduced reduce VBN cord-006870-f5w6fw6q 4106 9 in in IN cord-006870-f5w6fw6q 4106 10 the the DT cord-006870-f5w6fw6q 4106 11 non non JJ cord-006870-f5w6fw6q 4106 12 - - JJ cord-006870-f5w6fw6q 4106 13 PA PA NNP cord-006870-f5w6fw6q 4106 14 period period NN cord-006870-f5w6fw6q 4106 15 in in IN cord-006870-f5w6fw6q 4106 16 comparison comparison NN cord-006870-f5w6fw6q 4106 17 to to IN cord-006870-f5w6fw6q 4106 18 the the DT cord-006870-f5w6fw6q 4106 19 PA PA NNP cord-006870-f5w6fw6q 4106 20 period period NN cord-006870-f5w6fw6q 4106 21 ( ( -LRB- cord-006870-f5w6fw6q 4106 22 2 2 CD cord-006870-f5w6fw6q 4106 23 % % NN cord-006870-f5w6fw6q 4106 24 vs. vs. IN cord-006870-f5w6fw6q 4106 25 1 1 CD cord-006870-f5w6fw6q 4106 26 % % NN cord-006870-f5w6fw6q 4106 27 , , , cord-006870-f5w6fw6q 4106 28 p=1 p=1 NN cord-006870-f5w6fw6q 4106 29 ) ) -RRB- cord-006870-f5w6fw6q 4106 30 . . . cord-006870-f5w6fw6q 4107 1 The the DT cord-006870-f5w6fw6q 4107 2 cost cost NN cord-006870-f5w6fw6q 4107 3 of of IN cord-006870-f5w6fw6q 4107 4 antibiotics antibiotic NNS cord-006870-f5w6fw6q 4107 5 for for IN cord-006870-f5w6fw6q 4107 6 PA PA NNP cord-006870-f5w6fw6q 4107 7 patients patient NNS cord-006870-f5w6fw6q 4107 8 was be VBD cord-006870-f5w6fw6q 4107 9 $ $ $ cord-006870-f5w6fw6q 4107 10 5,499.62 5,499.62 CD cord-006870-f5w6fw6q 4107 11 , , , cord-006870-f5w6fw6q 4107 12 whereas whereas IN cord-006870-f5w6fw6q 4107 13 the the DT cord-006870-f5w6fw6q 4107 14 cost cost NN cord-006870-f5w6fw6q 4107 15 of of IN cord-006870-f5w6fw6q 4107 16 antibiotics antibiotic NNS cord-006870-f5w6fw6q 4107 17 for for IN cord-006870-f5w6fw6q 4107 18 the the DT cord-006870-f5w6fw6q 4107 19 non non JJ cord-006870-f5w6fw6q 4107 20 - - JJ cord-006870-f5w6fw6q 4107 21 PA PA NNP cord-006870-f5w6fw6q 4107 22 patients patient NNS cord-006870-f5w6fw6q 4107 23 was be VBD cord-006870-f5w6fw6q 4107 24 $ $ $ cord-006870-f5w6fw6q 4107 25 0 0 CD cord-006870-f5w6fw6q 4107 26 . . . cord-006870-f5w6fw6q 4108 1 On on IN cord-006870-f5w6fw6q 4108 2 a a DT cord-006870-f5w6fw6q 4108 3 per per IN cord-006870-f5w6fw6q 4108 4 patient patient JJ cord-006870-f5w6fw6q 4108 5 basis basis NN cord-006870-f5w6fw6q 4108 6 , , , cord-006870-f5w6fw6q 4108 7 the the DT cord-006870-f5w6fw6q 4108 8 cost cost NN cord-006870-f5w6fw6q 4108 9 associated associate VBN cord-006870-f5w6fw6q 4108 10 with with IN cord-006870-f5w6fw6q 4108 11 antibiotics antibiotic NNS cord-006870-f5w6fw6q 4108 12 and and CC cord-006870-f5w6fw6q 4108 13 resistant resistant JJ cord-006870-f5w6fw6q 4108 14 infections infection NNS cord-006870-f5w6fw6q 4108 15 was be VBD cord-006870-f5w6fw6q 4108 16 significantly significantly RB cord-006870-f5w6fw6q 4108 17 greater great JJR cord-006870-f5w6fw6q 4108 18 for for IN cord-006870-f5w6fw6q 4108 19 patients patient NNS cord-006870-f5w6fw6q 4108 20 who who WP cord-006870-f5w6fw6q 4108 21 received receive VBD cord-006870-f5w6fw6q 4108 22 PA PA NNP cord-006870-f5w6fw6q 4108 23 than than IN cord-006870-f5w6fw6q 4108 24 for for IN cord-006870-f5w6fw6q 4108 25 those those DT cord-006870-f5w6fw6q 4108 26 who who WP cord-006870-f5w6fw6q 4108 27 did do VBD cord-006870-f5w6fw6q 4108 28 not not RB cord-006870-f5w6fw6q 4108 29 ( ( -LRB- cord-006870-f5w6fw6q 4108 30 median median NN cord-006870-f5w6fw6q 4108 31 of of IN cord-006870-f5w6fw6q 4108 32 $ $ $ cord-006870-f5w6fw6q 4108 33 26.32 26.32 CD cord-006870-f5w6fw6q 4108 34 with with IN cord-006870-f5w6fw6q 4108 35 IQR IQR NNP cord-006870-f5w6fw6q 4108 36 $ $ $ cord-006870-f5w6fw6q 4108 37 9.87-$46.06 9.87-$46.06 CD cord-006870-f5w6fw6q 4108 38 vs. vs. IN cord-006870-f5w6fw6q 4108 39 median median NN cord-006870-f5w6fw6q 4108 40 of of IN cord-006870-f5w6fw6q 4108 41 $ $ $ cord-006870-f5w6fw6q 4108 42 0 0 CD cord-006870-f5w6fw6q 4108 43 with with IN cord-006870-f5w6fw6q 4108 44 IQR IQR NNP cord-006870-f5w6fw6q 4108 45 $ $ $ cord-006870-f5w6fw6q 4108 46 0-$0 0-$0 CD cord-006870-f5w6fw6q 4108 47 ; ; : cord-006870-f5w6fw6q 4108 48 p<0.0001 p<0.0001 NNP cord-006870-f5w6fw6q 4108 49 ) ) -RRB- cord-006870-f5w6fw6q 4108 50 . . . cord-006870-f5w6fw6q 4109 1 After after IN cord-006870-f5w6fw6q 4109 2 discontinuing discontinue VBG cord-006870-f5w6fw6q 4109 3 PA PA NNP cord-006870-f5w6fw6q 4109 4 for for IN cord-006870-f5w6fw6q 4109 5 patients patient NNS cord-006870-f5w6fw6q 4109 6 who who WP cord-006870-f5w6fw6q 4109 7 had have VBD cord-006870-f5w6fw6q 4109 8 instrumented instrument VBN cord-006870-f5w6fw6q 4109 9 spinal spinal JJ cord-006870-f5w6fw6q 4109 10 procedures procedure NNS cord-006870-f5w6fw6q 4109 11 , , , cord-006870-f5w6fw6q 4109 12 we -PRON- PRP cord-006870-f5w6fw6q 4109 13 did do VBD cord-006870-f5w6fw6q 4109 14 not not RB cord-006870-f5w6fw6q 4109 15 observe observe VB cord-006870-f5w6fw6q 4109 16 an an DT cord-006870-f5w6fw6q 4109 17 increase increase NN cord-006870-f5w6fw6q 4109 18 in in IN cord-006870-f5w6fw6q 4109 19 the the DT cord-006870-f5w6fw6q 4109 20 frequency frequency NN cord-006870-f5w6fw6q 4109 21 of of IN cord-006870-f5w6fw6q 4109 22 SSI SSI NNP cord-006870-f5w6fw6q 4109 23 . . . cord-006870-f5w6fw6q 4110 1 We -PRON- PRP cord-006870-f5w6fw6q 4110 2 did do VBD cord-006870-f5w6fw6q 4110 3 , , , cord-006870-f5w6fw6q 4110 4 however however RB cord-006870-f5w6fw6q 4110 5 , , , cord-006870-f5w6fw6q 4110 6 note note VBP cord-006870-f5w6fw6q 4110 7 that that IN cord-006870-f5w6fw6q 4110 8 there there EX cord-006870-f5w6fw6q 4110 9 was be VBD cord-006870-f5w6fw6q 4110 10 a a DT cord-006870-f5w6fw6q 4110 11 non non JJ cord-006870-f5w6fw6q 4110 12 - - JJ cord-006870-f5w6fw6q 4110 13 significant significant JJ cord-006870-f5w6fw6q 4110 14 decrease decrease NN cord-006870-f5w6fw6q 4110 15 in in IN cord-006870-f5w6fw6q 4110 16 the the DT cord-006870-f5w6fw6q 4110 17 frequency frequency NN cord-006870-f5w6fw6q 4110 18 of of IN cord-006870-f5w6fw6q 4110 19 growth growth NN cord-006870-f5w6fw6q 4110 20 of of IN cord-006870-f5w6fw6q 4110 21 resistant resistant JJ cord-006870-f5w6fw6q 4110 22 organisms organism NNS cord-006870-f5w6fw6q 4110 23 . . . cord-006870-f5w6fw6q 4111 1 These these DT cord-006870-f5w6fw6q 4111 2 findings finding NNS cord-006870-f5w6fw6q 4111 3 suggest suggest VBP cord-006870-f5w6fw6q 4111 4 that that IN cord-006870-f5w6fw6q 4111 5 patients patient NNS cord-006870-f5w6fw6q 4111 6 in in IN cord-006870-f5w6fw6q 4111 7 this this DT cord-006870-f5w6fw6q 4111 8 population population NN cord-006870-f5w6fw6q 4111 9 do do VBP cord-006870-f5w6fw6q 4111 10 not not RB cord-006870-f5w6fw6q 4111 11 need need VB cord-006870-f5w6fw6q 4111 12 PA PA NNP cord-006870-f5w6fw6q 4111 13 , , , cord-006870-f5w6fw6q 4111 14 and and CC cord-006870-f5w6fw6q 4111 15 complications complication NNS cord-006870-f5w6fw6q 4111 16 can can MD cord-006870-f5w6fw6q 4111 17 be be VB cord-006870-f5w6fw6q 4111 18 reduced reduce VBN cord-006870-f5w6fw6q 4111 19 if if IN cord-006870-f5w6fw6q 4111 20 PA PA NNP cord-006870-f5w6fw6q 4111 21 are be VBP cord-006870-f5w6fw6q 4111 22 withheld withhold VBN cord-006870-f5w6fw6q 4111 23 . . . cord-006870-f5w6fw6q 4112 1 The the DT cord-006870-f5w6fw6q 4112 2 development development NN cord-006870-f5w6fw6q 4112 3 of of IN cord-006870-f5w6fw6q 4112 4 flow flow NN cord-006870-f5w6fw6q 4112 5 - - HYPH cord-006870-f5w6fw6q 4112 6 diverting divert VBG cord-006870-f5w6fw6q 4112 7 stents stent NNS cord-006870-f5w6fw6q 4112 8 has have VBZ cord-006870-f5w6fw6q 4112 9 allowed allow VBN cord-006870-f5w6fw6q 4112 10 for for IN cord-006870-f5w6fw6q 4112 11 new new JJ cord-006870-f5w6fw6q 4112 12 treatment treatment NN cord-006870-f5w6fw6q 4112 13 options option NNS cord-006870-f5w6fw6q 4112 14 for for IN cord-006870-f5w6fw6q 4112 15 giant giant JJ cord-006870-f5w6fw6q 4112 16 vertebrobasilar vertebrobasilar NNP cord-006870-f5w6fw6q 4112 17 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4112 18 . . . cord-006870-f5w6fw6q 4113 1 However however RB cord-006870-f5w6fw6q 4113 2 , , , cord-006870-f5w6fw6q 4113 3 the the DT cord-006870-f5w6fw6q 4113 4 expertise expertise NN cord-006870-f5w6fw6q 4113 5 required require VBN cord-006870-f5w6fw6q 4113 6 to to TO cord-006870-f5w6fw6q 4113 7 perform perform VB cord-006870-f5w6fw6q 4113 8 these these DT cord-006870-f5w6fw6q 4113 9 procedures procedure NNS cord-006870-f5w6fw6q 4113 10 safely safely RB cord-006870-f5w6fw6q 4113 11 and and CC cord-006870-f5w6fw6q 4113 12 concerns concern NNS cord-006870-f5w6fw6q 4113 13 about about IN cord-006870-f5w6fw6q 4113 14 complications complication NNS cord-006870-f5w6fw6q 4113 15 continue continue VBP cord-006870-f5w6fw6q 4113 16 to to TO cord-006870-f5w6fw6q 4113 17 limit limit VB cord-006870-f5w6fw6q 4113 18 their -PRON- PRP$ cord-006870-f5w6fw6q 4113 19 use use NN cord-006870-f5w6fw6q 4113 20 . . . cord-006870-f5w6fw6q 4114 1 We -PRON- PRP cord-006870-f5w6fw6q 4114 2 sought seek VBD cord-006870-f5w6fw6q 4114 3 to to TO cord-006870-f5w6fw6q 4114 4 identify identify VB cord-006870-f5w6fw6q 4114 5 common common JJ cord-006870-f5w6fw6q 4114 6 complications complication NNS cord-006870-f5w6fw6q 4114 7 of of IN cord-006870-f5w6fw6q 4114 8 this this DT cord-006870-f5w6fw6q 4114 9 treatment treatment NN cord-006870-f5w6fw6q 4114 10 that that WDT cord-006870-f5w6fw6q 4114 11 can can MD cord-006870-f5w6fw6q 4114 12 be be VB cord-006870-f5w6fw6q 4114 13 anticipated anticipate VBN cord-006870-f5w6fw6q 4114 14 by by IN cord-006870-f5w6fw6q 4114 15 neurointensivists neurointensivist NNS cord-006870-f5w6fw6q 4114 16 , , , cord-006870-f5w6fw6q 4114 17 to to TO cord-006870-f5w6fw6q 4114 18 optimize optimize VB cord-006870-f5w6fw6q 4114 19 management management NN cord-006870-f5w6fw6q 4114 20 in in IN cord-006870-f5w6fw6q 4114 21 the the DT cord-006870-f5w6fw6q 4114 22 postoperative postoperative JJ cord-006870-f5w6fw6q 4114 23 period period NN cord-006870-f5w6fw6q 4114 24 . . . cord-006870-f5w6fw6q 4115 1 We -PRON- PRP cord-006870-f5w6fw6q 4115 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 4115 3 reviewed review VBD cord-006870-f5w6fw6q 4115 4 our -PRON- PRP$ cord-006870-f5w6fw6q 4115 5 hospital hospital NN cord-006870-f5w6fw6q 4115 6 database database NN cord-006870-f5w6fw6q 4115 7 of of IN cord-006870-f5w6fw6q 4115 8 treated treat VBN cord-006870-f5w6fw6q 4115 9 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4115 10 to to TO cord-006870-f5w6fw6q 4115 11 identify identify VB cord-006870-f5w6fw6q 4115 12 those those DT cord-006870-f5w6fw6q 4115 13 with with IN cord-006870-f5w6fw6q 4115 14 giant giant JJ cord-006870-f5w6fw6q 4115 15 vertebrobasilar vertebrobasilar NNP cord-006870-f5w6fw6q 4115 16 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4115 17 . . . cord-006870-f5w6fw6q 4116 1 Medical medical JJ cord-006870-f5w6fw6q 4116 2 and and CC cord-006870-f5w6fw6q 4116 3 neurological neurological JJ cord-006870-f5w6fw6q 4116 4 complications complication NNS cord-006870-f5w6fw6q 4116 5 were be VBD cord-006870-f5w6fw6q 4116 6 recorded record VBN cord-006870-f5w6fw6q 4116 7 . . . cord-006870-f5w6fw6q 4117 1 Six six CD cord-006870-f5w6fw6q 4117 2 patients patient NNS cord-006870-f5w6fw6q 4117 3 ( ( -LRB- cord-006870-f5w6fw6q 4117 4 5 5 CD cord-006870-f5w6fw6q 4117 5 male male NN cord-006870-f5w6fw6q 4117 6 , , , cord-006870-f5w6fw6q 4117 7 1 1 CD cord-006870-f5w6fw6q 4117 8 female female JJ cord-006870-f5w6fw6q 4117 9 ) ) -RRB- cord-006870-f5w6fw6q 4117 10 underwent undergo VBD cord-006870-f5w6fw6q 4117 11 treatment treatment NN cord-006870-f5w6fw6q 4117 12 of of IN cord-006870-f5w6fw6q 4117 13 giant giant JJ cord-006870-f5w6fw6q 4117 14 vertebrobasilar vertebrobasilar NNP cord-006870-f5w6fw6q 4117 15 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4117 16 with with IN cord-006870-f5w6fw6q 4117 17 pipeline pipeline NN cord-006870-f5w6fw6q 4117 18 embolization embolization NN cord-006870-f5w6fw6q 4117 19 devices device NNS cord-006870-f5w6fw6q 4117 20 . . . cord-006870-f5w6fw6q 4118 1 Five five CD cord-006870-f5w6fw6q 4118 2 received receive VBN cord-006870-f5w6fw6q 4118 3 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4118 4 coiling coiling NN cord-006870-f5w6fw6q 4118 5 . . . cord-006870-f5w6fw6q 4119 1 Frequently frequently RB cord-006870-f5w6fw6q 4119 2 reported report VBD cord-006870-f5w6fw6q 4119 3 pre pre JJ cord-006870-f5w6fw6q 4119 4 - - JJ cord-006870-f5w6fw6q 4119 5 procedure procedure JJ cord-006870-f5w6fw6q 4119 6 symptoms symptom NNS cord-006870-f5w6fw6q 4119 7 were be VBD cord-006870-f5w6fw6q 4119 8 dysphagia dysphagia NNP cord-006870-f5w6fw6q 4119 9 ( ( -LRB- cord-006870-f5w6fw6q 4119 10 n=4 n=4 NNP cord-006870-f5w6fw6q 4119 11 ) ) -RRB- cord-006870-f5w6fw6q 4119 12 , , , cord-006870-f5w6fw6q 4119 13 diplopia diplopia FW cord-006870-f5w6fw6q 4119 14 ( ( -LRB- cord-006870-f5w6fw6q 4119 15 n=3 n=3 NN cord-006870-f5w6fw6q 4119 16 ) ) -RRB- cord-006870-f5w6fw6q 4119 17 , , , cord-006870-f5w6fw6q 4119 18 dysarthria dysarthria FW cord-006870-f5w6fw6q 4119 19 ( ( -LRB- cord-006870-f5w6fw6q 4119 20 n=3 n=3 NN cord-006870-f5w6fw6q 4119 21 ) ) -RRB- cord-006870-f5w6fw6q 4119 22 , , , cord-006870-f5w6fw6q 4119 23 facial facial JJ cord-006870-f5w6fw6q 4119 24 weakness weakness NN cord-006870-f5w6fw6q 4119 25 ( ( -LRB- cord-006870-f5w6fw6q 4119 26 n=3 n=3 NN cord-006870-f5w6fw6q 4119 27 ) ) -RRB- cord-006870-f5w6fw6q 4119 28 , , , cord-006870-f5w6fw6q 4119 29 hemiparesis hemiparesis NNP cord-006870-f5w6fw6q 4119 30 ( ( -LRB- cord-006870-f5w6fw6q 4119 31 n=2 n=2 NNP cord-006870-f5w6fw6q 4119 32 ) ) -RRB- cord-006870-f5w6fw6q 4119 33 , , , cord-006870-f5w6fw6q 4119 34 gaze gaze NN cord-006870-f5w6fw6q 4119 35 palsy palsy NN cord-006870-f5w6fw6q 4119 36 ( ( -LRB- cord-006870-f5w6fw6q 4119 37 n=2 n=2 NNS cord-006870-f5w6fw6q 4119 38 ) ) -RRB- cord-006870-f5w6fw6q 4119 39 , , , cord-006870-f5w6fw6q 4119 40 and and CC cord-006870-f5w6fw6q 4119 41 nystagmus nystagmus NN cord-006870-f5w6fw6q 4119 42 ( ( -LRB- cord-006870-f5w6fw6q 4119 43 n=2 n=2 NNS cord-006870-f5w6fw6q 4119 44 ) ) -RRB- cord-006870-f5w6fw6q 4119 45 . . . cord-006870-f5w6fw6q 4120 1 Five five CD cord-006870-f5w6fw6q 4120 2 patients patient NNS cord-006870-f5w6fw6q 4120 3 ambulated ambulate VBN cord-006870-f5w6fw6q 4120 4 normally normally RB cord-006870-f5w6fw6q 4120 5 . . . cord-006870-f5w6fw6q 4121 1 Due due IN cord-006870-f5w6fw6q 4121 2 to to IN cord-006870-f5w6fw6q 4121 3 concerns concern NNS cord-006870-f5w6fw6q 4121 4 about about IN cord-006870-f5w6fw6q 4121 5 necessary necessary JJ cord-006870-f5w6fw6q 4121 6 procedures procedure NNS cord-006870-f5w6fw6q 4121 7 after after IN cord-006870-f5w6fw6q 4121 8 stenting stente VBG cord-006870-f5w6fw6q 4121 9 when when WRB cord-006870-f5w6fw6q 4121 10 on on IN cord-006870-f5w6fw6q 4121 11 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 4121 12 therapy therapy NN cord-006870-f5w6fw6q 4121 13 , , , cord-006870-f5w6fw6q 4121 14 three three CD cord-006870-f5w6fw6q 4121 15 patients patient NNS cord-006870-f5w6fw6q 4121 16 received receive VBD cord-006870-f5w6fw6q 4121 17 prophylactic prophylactic JJ cord-006870-f5w6fw6q 4121 18 ventriculoperitoneal ventriculoperitoneal NN cord-006870-f5w6fw6q 4121 19 shunts shunt NNS cord-006870-f5w6fw6q 4121 20 , , , cord-006870-f5w6fw6q 4121 21 two two CD cord-006870-f5w6fw6q 4121 22 underwent undergo VBD cord-006870-f5w6fw6q 4121 23 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 4121 24 , , , cord-006870-f5w6fw6q 4121 25 and and CC cord-006870-f5w6fw6q 4121 26 two two CD cord-006870-f5w6fw6q 4121 27 underwent undergo VBD cord-006870-f5w6fw6q 4121 28 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4121 29 . . . cord-006870-f5w6fw6q 4122 1 Angiography angiography NN cord-006870-f5w6fw6q 4122 2 confirmed confirm VBD cord-006870-f5w6fw6q 4122 3 successful successful JJ cord-006870-f5w6fw6q 4122 4 aneurysm aneurysm NN cord-006870-f5w6fw6q 4122 5 embolization embolization NN cord-006870-f5w6fw6q 4122 6 in in IN cord-006870-f5w6fw6q 4122 7 all all DT cord-006870-f5w6fw6q 4122 8 patients patient NNS cord-006870-f5w6fw6q 4122 9 . . . cord-006870-f5w6fw6q 4123 1 Postoperatively postoperatively RB cord-006870-f5w6fw6q 4123 2 , , , cord-006870-f5w6fw6q 4123 3 all all DT cord-006870-f5w6fw6q 4123 4 patients patient NNS cord-006870-f5w6fw6q 4123 5 developed develop VBD cord-006870-f5w6fw6q 4123 6 new new JJ cord-006870-f5w6fw6q 4123 7 or or CC cord-006870-f5w6fw6q 4123 8 worsened worsen VBD cord-006870-f5w6fw6q 4123 9 symptoms symptom NNS cord-006870-f5w6fw6q 4123 10 attributed attribute VBN cord-006870-f5w6fw6q 4123 11 to to IN cord-006870-f5w6fw6q 4123 12 brainstem brainstem NN cord-006870-f5w6fw6q 4123 13 edema edema NN cord-006870-f5w6fw6q 4123 14 , , , cord-006870-f5w6fw6q 4123 15 including include VBG cord-006870-f5w6fw6q 4123 16 hemiparesis hemiparesis NNP cord-006870-f5w6fw6q 4123 17 ( ( -LRB- cord-006870-f5w6fw6q 4123 18 n=4 n=4 NNP cord-006870-f5w6fw6q 4123 19 ) ) -RRB- cord-006870-f5w6fw6q 4123 20 , , , cord-006870-f5w6fw6q 4123 21 facial facial JJ cord-006870-f5w6fw6q 4123 22 weakness weakness NN cord-006870-f5w6fw6q 4123 23 ( ( -LRB- cord-006870-f5w6fw6q 4123 24 n=4 n=4 NNP cord-006870-f5w6fw6q 4123 25 ) ) -RRB- cord-006870-f5w6fw6q 4123 26 , , , cord-006870-f5w6fw6q 4123 27 dysphagia dysphagia NNP cord-006870-f5w6fw6q 4123 28 ( ( -LRB- cord-006870-f5w6fw6q 4123 29 n=4 n=4 NNP cord-006870-f5w6fw6q 4123 30 ) ) -RRB- cord-006870-f5w6fw6q 4123 31 , , , cord-006870-f5w6fw6q 4123 32 diplopia diplopia NN cord-006870-f5w6fw6q 4123 33 ( ( -LRB- cord-006870-f5w6fw6q 4123 34 n=4 n=4 NNP cord-006870-f5w6fw6q 4123 35 ) ) -RRB- cord-006870-f5w6fw6q 4123 36 , , , cord-006870-f5w6fw6q 4123 37 nystagmus nystagmus NN cord-006870-f5w6fw6q 4123 38 ( ( -LRB- cord-006870-f5w6fw6q 4123 39 n=3 n=3 NN cord-006870-f5w6fw6q 4123 40 ) ) -RRB- cord-006870-f5w6fw6q 4123 41 , , , cord-006870-f5w6fw6q 4123 42 gaze gaze NN cord-006870-f5w6fw6q 4123 43 palsy palsy NN cord-006870-f5w6fw6q 4123 44 ( ( -LRB- cord-006870-f5w6fw6q 4123 45 n=3 n=3 NN cord-006870-f5w6fw6q 4123 46 ) ) -RRB- cord-006870-f5w6fw6q 4123 47 , , , cord-006870-f5w6fw6q 4123 48 and and CC cord-006870-f5w6fw6q 4123 49 dysarthria dysarthria NN cord-006870-f5w6fw6q 4123 50 ( ( -LRB- cord-006870-f5w6fw6q 4123 51 n=3 n=3 NN cord-006870-f5w6fw6q 4123 52 ) ) -RRB- cord-006870-f5w6fw6q 4123 53 . . . cord-006870-f5w6fw6q 4124 1 Neurological neurological JJ cord-006870-f5w6fw6q 4124 2 symptoms symptom NNS cord-006870-f5w6fw6q 4124 3 were be VBD cord-006870-f5w6fw6q 4124 4 treated treat VBN cord-006870-f5w6fw6q 4124 5 with with IN cord-006870-f5w6fw6q 4124 6 steroids steroid NNS cord-006870-f5w6fw6q 4124 7 , , , cord-006870-f5w6fw6q 4124 8 with with IN cord-006870-f5w6fw6q 4124 9 most most JJS cord-006870-f5w6fw6q 4124 10 symptoms symptom NNS cord-006870-f5w6fw6q 4124 11 subsiding subside VBG cord-006870-f5w6fw6q 4124 12 by by IN cord-006870-f5w6fw6q 4124 13 discharge discharge NN cord-006870-f5w6fw6q 4124 14 . . . cord-006870-f5w6fw6q 4125 1 Five five CD cord-006870-f5w6fw6q 4125 2 patients patient NNS cord-006870-f5w6fw6q 4125 3 had have VBD cord-006870-f5w6fw6q 4125 4 medical medical JJ cord-006870-f5w6fw6q 4125 5 complications complication NNS cord-006870-f5w6fw6q 4125 6 , , , cord-006870-f5w6fw6q 4125 7 including include VBG cord-006870-f5w6fw6q 4125 8 pneumonia pneumonia NN cord-006870-f5w6fw6q 4125 9 ( ( -LRB- cord-006870-f5w6fw6q 4125 10 n=2 n=2 NNS cord-006870-f5w6fw6q 4125 11 ) ) -RRB- cord-006870-f5w6fw6q 4125 12 , , , cord-006870-f5w6fw6q 4125 13 respiratory respiratory JJ cord-006870-f5w6fw6q 4125 14 failure failure NN cord-006870-f5w6fw6q 4125 15 ( ( -LRB- cord-006870-f5w6fw6q 4125 16 n=2 n=2 NNS cord-006870-f5w6fw6q 4125 17 ) ) -RRB- cord-006870-f5w6fw6q 4125 18 , , , cord-006870-f5w6fw6q 4125 19 gastrointestinal gastrointestinal JJ cord-006870-f5w6fw6q 4125 20 bleeding bleeding NN cord-006870-f5w6fw6q 4125 21 ( ( -LRB- cord-006870-f5w6fw6q 4125 22 n=2 n=2 NNS cord-006870-f5w6fw6q 4125 23 ) ) -RRB- cord-006870-f5w6fw6q 4125 24 , , , cord-006870-f5w6fw6q 4125 25 arrhythmia arrhythmia NN cord-006870-f5w6fw6q 4125 26 ( ( -LRB- cord-006870-f5w6fw6q 4125 27 n=2 n=2 NNS cord-006870-f5w6fw6q 4125 28 ) ) -RRB- cord-006870-f5w6fw6q 4125 29 , , , cord-006870-f5w6fw6q 4125 30 urinary urinary JJ cord-006870-f5w6fw6q 4125 31 tract tract NN cord-006870-f5w6fw6q 4125 32 infection infection NN cord-006870-f5w6fw6q 4125 33 ( ( -LRB- cord-006870-f5w6fw6q 4125 34 n=1 n=1 CD cord-006870-f5w6fw6q 4125 35 ) ) -RRB- cord-006870-f5w6fw6q 4125 36 , , , cord-006870-f5w6fw6q 4125 37 and and CC cord-006870-f5w6fw6q 4125 38 myocardial myocardial JJ cord-006870-f5w6fw6q 4125 39 infarction infarction NN cord-006870-f5w6fw6q 4125 40 ( ( -LRB- cord-006870-f5w6fw6q 4125 41 n=1 n=1 FW cord-006870-f5w6fw6q 4125 42 ) ) -RRB- cord-006870-f5w6fw6q 4125 43 . . . cord-006870-f5w6fw6q 4126 1 Two two CD cord-006870-f5w6fw6q 4126 2 patients patient NNS cord-006870-f5w6fw6q 4126 3 were be VBD cord-006870-f5w6fw6q 4126 4 re re VBN cord-006870-f5w6fw6q 4126 5 - - VBN cord-006870-f5w6fw6q 4126 6 intubated intubate VBN cord-006870-f5w6fw6q 4126 7 , , , cord-006870-f5w6fw6q 4126 8 three three CD cord-006870-f5w6fw6q 4126 9 underwent undergo VBD cord-006870-f5w6fw6q 4126 10 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 4126 11 , , , cord-006870-f5w6fw6q 4126 12 and and CC cord-006870-f5w6fw6q 4126 13 one one CD cord-006870-f5w6fw6q 4126 14 underwent undergo VBD cord-006870-f5w6fw6q 4126 15 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4126 16 . . . cord-006870-f5w6fw6q 4127 1 Functional functional JJ cord-006870-f5w6fw6q 4127 2 status status NN cord-006870-f5w6fw6q 4127 3 at at IN cord-006870-f5w6fw6q 4127 4 3-months 3-months CD cord-006870-f5w6fw6q 4127 5 was be VBD cord-006870-f5w6fw6q 4127 6 available available JJ cord-006870-f5w6fw6q 4127 7 for for IN cord-006870-f5w6fw6q 4127 8 five five CD cord-006870-f5w6fw6q 4127 9 patients patient NNS cord-006870-f5w6fw6q 4127 10 . . . cord-006870-f5w6fw6q 4128 1 Three three CD cord-006870-f5w6fw6q 4128 2 achieved achieve VBN cord-006870-f5w6fw6q 4128 3 modified modify VBN cord-006870-f5w6fw6q 4128 4 Rankin Rankin NNP cord-006870-f5w6fw6q 4128 5 Scale Scale NNP cord-006870-f5w6fw6q 4128 6 scores score NNS cord-006870-f5w6fw6q 4128 7 between between IN cord-006870-f5w6fw6q 4128 8 0 0 CD cord-006870-f5w6fw6q 4128 9 - - SYM cord-006870-f5w6fw6q 4128 10 2 2 CD cord-006870-f5w6fw6q 4128 11 , , , cord-006870-f5w6fw6q 4128 12 one one CD cord-006870-f5w6fw6q 4128 13 regressed regress VBD cord-006870-f5w6fw6q 4128 14 to to IN cord-006870-f5w6fw6q 4128 15 a a DT cord-006870-f5w6fw6q 4128 16 5 5 CD cord-006870-f5w6fw6q 4128 17 , , , cord-006870-f5w6fw6q 4128 18 and and CC cord-006870-f5w6fw6q 4128 19 one one CD cord-006870-f5w6fw6q 4128 20 died die VBD cord-006870-f5w6fw6q 4128 21 . . . cord-006870-f5w6fw6q 4129 1 The the DT cord-006870-f5w6fw6q 4129 2 treatment treatment NN cord-006870-f5w6fw6q 4129 3 of of IN cord-006870-f5w6fw6q 4129 4 giant giant JJ cord-006870-f5w6fw6q 4129 5 vertebrobasilar vertebrobasilar NNP cord-006870-f5w6fw6q 4129 6 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4129 7 presents present VBZ cord-006870-f5w6fw6q 4129 8 significant significant JJ cord-006870-f5w6fw6q 4129 9 challenges challenge NNS cord-006870-f5w6fw6q 4129 10 . . . cord-006870-f5w6fw6q 4130 1 Practitioners practitioner NNS cord-006870-f5w6fw6q 4130 2 should should MD cord-006870-f5w6fw6q 4130 3 anticipate anticipate VB cord-006870-f5w6fw6q 4130 4 temporary temporary JJ cord-006870-f5w6fw6q 4130 5 postoperative postoperative JJ cord-006870-f5w6fw6q 4130 6 neurological neurological JJ cord-006870-f5w6fw6q 4130 7 worsening worsen VBG cord-006870-f5w6fw6q 4130 8 and and CC cord-006870-f5w6fw6q 4130 9 various various JJ cord-006870-f5w6fw6q 4130 10 medical medical JJ cord-006870-f5w6fw6q 4130 11 complications complication NNS cord-006870-f5w6fw6q 4130 12 . . . cord-006870-f5w6fw6q 4131 1 Prophylactic prophylactic JJ cord-006870-f5w6fw6q 4131 2 shunt shunt NN cord-006870-f5w6fw6q 4131 3 placement placement NN cord-006870-f5w6fw6q 4131 4 , , , cord-006870-f5w6fw6q 4131 5 gastrostomy gastrostomy NNP cord-006870-f5w6fw6q 4131 6 , , , cord-006870-f5w6fw6q 4131 7 and/or and/or CC cord-006870-f5w6fw6q 4131 8 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4131 9 should should MD cord-006870-f5w6fw6q 4131 10 be be VB cord-006870-f5w6fw6q 4131 11 considered consider VBN cord-006870-f5w6fw6q 4131 12 in in IN cord-006870-f5w6fw6q 4131 13 patients patient NNS cord-006870-f5w6fw6q 4131 14 anticipated anticipate VBN cord-006870-f5w6fw6q 4131 15 to to TO cord-006870-f5w6fw6q 4131 16 likely likely RB cord-006870-f5w6fw6q 4131 17 need need VB cord-006870-f5w6fw6q 4131 18 these these DT cord-006870-f5w6fw6q 4131 19 procedures procedure NNS cord-006870-f5w6fw6q 4131 20 after after IN cord-006870-f5w6fw6q 4131 21 treatment treatment NN cord-006870-f5w6fw6q 4131 22 . . . cord-006870-f5w6fw6q 4132 1 Ventriculostomy ventriculostomy NN cord-006870-f5w6fw6q 4132 2 - - HYPH cord-006870-f5w6fw6q 4132 3 related relate VBN cord-006870-f5w6fw6q 4132 4 infection infection NN cord-006870-f5w6fw6q 4132 5 ( ( -LRB- cord-006870-f5w6fw6q 4132 6 VRI VRI NNP cord-006870-f5w6fw6q 4132 7 ) ) -RRB- cord-006870-f5w6fw6q 4132 8 remains remain VBZ cord-006870-f5w6fw6q 4132 9 a a DT cord-006870-f5w6fw6q 4132 10 major major JJ cord-006870-f5w6fw6q 4132 11 complication complication NN cord-006870-f5w6fw6q 4132 12 of of IN cord-006870-f5w6fw6q 4132 13 external external JJ cord-006870-f5w6fw6q 4132 14 ventricular ventricular JJ cord-006870-f5w6fw6q 4132 15 drain drain NN cord-006870-f5w6fw6q 4132 16 ( ( -LRB- cord-006870-f5w6fw6q 4132 17 EVD EVD NNP cord-006870-f5w6fw6q 4132 18 ) ) -RRB- cord-006870-f5w6fw6q 4132 19 placement placement NN cord-006870-f5w6fw6q 4132 20 . . . cord-006870-f5w6fw6q 4133 1 Historically historically RB cord-006870-f5w6fw6q 4133 2 , , , cord-006870-f5w6fw6q 4133 3 prophylactic prophylactic JJ cord-006870-f5w6fw6q 4133 4 antimicrobials antimicrobial NNS cord-006870-f5w6fw6q 4133 5 are be VBP cord-006870-f5w6fw6q 4133 6 utilized utilize VBN cord-006870-f5w6fw6q 4133 7 to to TO cord-006870-f5w6fw6q 4133 8 decrease decrease VB cord-006870-f5w6fw6q 4133 9 the the DT cord-006870-f5w6fw6q 4133 10 incidence incidence NN cord-006870-f5w6fw6q 4133 11 of of IN cord-006870-f5w6fw6q 4133 12 VRI VRI NNP cord-006870-f5w6fw6q 4133 13 after after IN cord-006870-f5w6fw6q 4133 14 EVD EVD NNP cord-006870-f5w6fw6q 4133 15 placement placement NN cord-006870-f5w6fw6q 4133 16 . . . cord-006870-f5w6fw6q 4134 1 Recent recent JJ cord-006870-f5w6fw6q 4134 2 guidelines guideline NNS cord-006870-f5w6fw6q 4134 3 for for IN cord-006870-f5w6fw6q 4134 4 the the DT cord-006870-f5w6fw6q 4134 5 insertion insertion NN cord-006870-f5w6fw6q 4134 6 and and CC cord-006870-f5w6fw6q 4134 7 management management NN cord-006870-f5w6fw6q 4134 8 of of IN cord-006870-f5w6fw6q 4134 9 EVDs EVDs NNP cord-006870-f5w6fw6q 4134 10 recommend recommend VBP cord-006870-f5w6fw6q 4134 11 a a DT cord-006870-f5w6fw6q 4134 12 single single JJ cord-006870-f5w6fw6q 4134 13 preoperative preoperative JJ cord-006870-f5w6fw6q 4134 14 dose dose NN cord-006870-f5w6fw6q 4134 15 prior prior RB cord-006870-f5w6fw6q 4134 16 to to IN cord-006870-f5w6fw6q 4134 17 EVD EVD NNP cord-006870-f5w6fw6q 4134 18 insertion insertion NN cord-006870-f5w6fw6q 4134 19 and and CC cord-006870-f5w6fw6q 4134 20 urges urge VBZ cord-006870-f5w6fw6q 4134 21 against against IN cord-006870-f5w6fw6q 4134 22 the the DT cord-006870-f5w6fw6q 4134 23 use use NN cord-006870-f5w6fw6q 4134 24 of of IN cord-006870-f5w6fw6q 4134 25 duration duration NN cord-006870-f5w6fw6q 4134 26 antibiotic antibiotic JJ cord-006870-f5w6fw6q 4134 27 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4134 28 . . . cord-006870-f5w6fw6q 4135 1 Prior prior RB cord-006870-f5w6fw6q 4135 2 to to IN cord-006870-f5w6fw6q 4135 3 the the DT cord-006870-f5w6fw6q 4135 4 publication publication NN cord-006870-f5w6fw6q 4135 5 of of IN cord-006870-f5w6fw6q 4135 6 this this DT cord-006870-f5w6fw6q 4135 7 guideline guideline NN cord-006870-f5w6fw6q 4135 8 , , , cord-006870-f5w6fw6q 4135 9 we -PRON- PRP cord-006870-f5w6fw6q 4135 10 hypothesized hypothesize VBD cord-006870-f5w6fw6q 4135 11 that that IN cord-006870-f5w6fw6q 4135 12 significant significant JJ cord-006870-f5w6fw6q 4135 13 variations variation NNS cord-006870-f5w6fw6q 4135 14 existed exist VBD cord-006870-f5w6fw6q 4135 15 among among IN cord-006870-f5w6fw6q 4135 16 institutions institution NNS cord-006870-f5w6fw6q 4135 17 with with IN cord-006870-f5w6fw6q 4135 18 respect respect NN cord-006870-f5w6fw6q 4135 19 to to IN cord-006870-f5w6fw6q 4135 20 antibiotic antibiotic JJ cord-006870-f5w6fw6q 4135 21 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4135 22 practices practice NNS cord-006870-f5w6fw6q 4135 23 in in IN cord-006870-f5w6fw6q 4135 24 this this DT cord-006870-f5w6fw6q 4135 25 setting setting NN cord-006870-f5w6fw6q 4135 26 . . . cord-006870-f5w6fw6q 4136 1 The the DT cord-006870-f5w6fw6q 4136 2 purpose purpose NN cord-006870-f5w6fw6q 4136 3 of of IN cord-006870-f5w6fw6q 4136 4 this this DT cord-006870-f5w6fw6q 4136 5 practice practice NN cord-006870-f5w6fw6q 4136 6 survey survey NN cord-006870-f5w6fw6q 4136 7 was be VBD cord-006870-f5w6fw6q 4136 8 to to TO cord-006870-f5w6fw6q 4136 9 determine determine VB cord-006870-f5w6fw6q 4136 10 trends trend NNS cord-006870-f5w6fw6q 4136 11 in in IN cord-006870-f5w6fw6q 4136 12 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4136 13 prophylactic prophylactic JJ cord-006870-f5w6fw6q 4136 14 strategies strategy NNS cord-006870-f5w6fw6q 4136 15 utilized utilize VBN cord-006870-f5w6fw6q 4136 16 by by IN cord-006870-f5w6fw6q 4136 17 various various JJ cord-006870-f5w6fw6q 4136 18 healthcare healthcare NN cord-006870-f5w6fw6q 4136 19 institutions institution NNS cord-006870-f5w6fw6q 4136 20 for for IN cord-006870-f5w6fw6q 4136 21 EVD EVD NNP cord-006870-f5w6fw6q 4136 22 placement placement NN cord-006870-f5w6fw6q 4136 23 prior prior RB cord-006870-f5w6fw6q 4136 24 to to IN cord-006870-f5w6fw6q 4136 25 publication publication NN cord-006870-f5w6fw6q 4136 26 of of IN cord-006870-f5w6fw6q 4136 27 the the DT cord-006870-f5w6fw6q 4136 28 2016 2016 CD cord-006870-f5w6fw6q 4136 29 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 4136 30 Care Care NNP cord-006870-f5w6fw6q 4136 31 Society Society NNP cord-006870-f5w6fw6q 4136 32 ( ( -LRB- cord-006870-f5w6fw6q 4136 33 NCS NCS NNP cord-006870-f5w6fw6q 4136 34 ) ) -RRB- cord-006870-f5w6fw6q 4136 35 evidence evidence NN cord-006870-f5w6fw6q 4136 36 - - HYPH cord-006870-f5w6fw6q 4136 37 based base VBN cord-006870-f5w6fw6q 4136 38 guidelines guideline NNS cord-006870-f5w6fw6q 4136 39 for for IN cord-006870-f5w6fw6q 4136 40 the the DT cord-006870-f5w6fw6q 4136 41 insertion insertion NN cord-006870-f5w6fw6q 4136 42 and and CC cord-006870-f5w6fw6q 4136 43 management management NN cord-006870-f5w6fw6q 4136 44 of of IN cord-006870-f5w6fw6q 4136 45 EVDs EVDs NNP cord-006870-f5w6fw6q 4136 46 . . . cord-006870-f5w6fw6q 4137 1 A a DT cord-006870-f5w6fw6q 4137 2 seven seven CD cord-006870-f5w6fw6q 4137 3 - - HYPH cord-006870-f5w6fw6q 4137 4 question question NN cord-006870-f5w6fw6q 4137 5 practice practice NN cord-006870-f5w6fw6q 4137 6 survey survey NN cord-006870-f5w6fw6q 4137 7 on on IN cord-006870-f5w6fw6q 4137 8 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4137 9 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4137 10 for for IN cord-006870-f5w6fw6q 4137 11 EVD EVD NNP cord-006870-f5w6fw6q 4137 12 placement placement NN cord-006870-f5w6fw6q 4137 13 was be VBD cord-006870-f5w6fw6q 4137 14 distributed distribute VBN cord-006870-f5w6fw6q 4137 15 to to IN cord-006870-f5w6fw6q 4137 16 active active JJ cord-006870-f5w6fw6q 4137 17 pharmacist pharmacist NN cord-006870-f5w6fw6q 4137 18 members member NNS cord-006870-f5w6fw6q 4137 19 of of IN cord-006870-f5w6fw6q 4137 20 the the DT cord-006870-f5w6fw6q 4137 21 NCS NCS NNP cord-006870-f5w6fw6q 4137 22 by by IN cord-006870-f5w6fw6q 4137 23 email email NN cord-006870-f5w6fw6q 4137 24 and and CC cord-006870-f5w6fw6q 4137 25 open open JJ cord-006870-f5w6fw6q 4137 26 for for IN cord-006870-f5w6fw6q 4137 27 response response NN cord-006870-f5w6fw6q 4137 28 from from IN cord-006870-f5w6fw6q 4137 29 12/22/15 12/22/15 CD cord-006870-f5w6fw6q 4137 30 to to IN cord-006870-f5w6fw6q 4137 31 1/25/2016 1/25/2016 CD cord-006870-f5w6fw6q 4137 32 . . . cord-006870-f5w6fw6q 4138 1 The the DT cord-006870-f5w6fw6q 4138 2 following following JJ cord-006870-f5w6fw6q 4138 3 information information NN cord-006870-f5w6fw6q 4138 4 was be VBD cord-006870-f5w6fw6q 4138 5 collected collect VBN cord-006870-f5w6fw6q 4138 6 : : : cord-006870-f5w6fw6q 4138 7 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4138 8 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4138 9 regimen regimen NN cord-006870-f5w6fw6q 4138 10 utilized utilize VBN cord-006870-f5w6fw6q 4138 11 , , , cord-006870-f5w6fw6q 4138 12 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 4138 13 class class NN cord-006870-f5w6fw6q 4138 14 , , , cord-006870-f5w6fw6q 4138 15 utilization utilization NN cord-006870-f5w6fw6q 4138 16 of of IN cord-006870-f5w6fw6q 4138 17 impregnated impregnate VBN cord-006870-f5w6fw6q 4138 18 catheters catheter NNS cord-006870-f5w6fw6q 4138 19 , , , cord-006870-f5w6fw6q 4138 20 and and CC cord-006870-f5w6fw6q 4138 21 institution institution NN cord-006870-f5w6fw6q 4138 22 guidance guidance NN cord-006870-f5w6fw6q 4138 23 . . . cord-006870-f5w6fw6q 4139 1 Survey survey NN cord-006870-f5w6fw6q 4139 2 results result NNS cord-006870-f5w6fw6q 4139 3 were be VBD cord-006870-f5w6fw6q 4139 4 analyzed analyze VBN cord-006870-f5w6fw6q 4139 5 for for IN cord-006870-f5w6fw6q 4139 6 trends trend NNS cord-006870-f5w6fw6q 4139 7 in in IN cord-006870-f5w6fw6q 4139 8 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4139 9 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4139 10 in in IN cord-006870-f5w6fw6q 4139 11 the the DT cord-006870-f5w6fw6q 4139 12 setting setting NN cord-006870-f5w6fw6q 4139 13 of of IN cord-006870-f5w6fw6q 4139 14 EVD EVD NNP cord-006870-f5w6fw6q 4139 15 placement placement NN cord-006870-f5w6fw6q 4139 16 . . . cord-006870-f5w6fw6q 4140 1 Respondents respondent NNS cord-006870-f5w6fw6q 4140 2 ( ( -LRB- cord-006870-f5w6fw6q 4140 3 43/105 43/105 CD cord-006870-f5w6fw6q 4140 4 , , , cord-006870-f5w6fw6q 4140 5 41 41 CD cord-006870-f5w6fw6q 4140 6 % % NN cord-006870-f5w6fw6q 4140 7 response response NN cord-006870-f5w6fw6q 4140 8 rate rate NN cord-006870-f5w6fw6q 4140 9 ) ) -RRB- cord-006870-f5w6fw6q 4140 10 from from IN cord-006870-f5w6fw6q 4140 11 43 43 CD cord-006870-f5w6fw6q 4140 12 institutions institution NNS cord-006870-f5w6fw6q 4140 13 completed complete VBD cord-006870-f5w6fw6q 4140 14 a a DT cord-006870-f5w6fw6q 4140 15 seven seven CD cord-006870-f5w6fw6q 4140 16 - - HYPH cord-006870-f5w6fw6q 4140 17 question question NN cord-006870-f5w6fw6q 4140 18 EVD EVD NNP cord-006870-f5w6fw6q 4140 19 management management NN cord-006870-f5w6fw6q 4140 20 survey survey NN cord-006870-f5w6fw6q 4140 21 . . . cord-006870-f5w6fw6q 4141 1 Most Most JJS cord-006870-f5w6fw6q 4141 2 institutions institution NNS cord-006870-f5w6fw6q 4141 3 initiate initiate VBP cord-006870-f5w6fw6q 4141 4 a a DT cord-006870-f5w6fw6q 4141 5 single single JJ cord-006870-f5w6fw6q 4141 6 dose dose NN cord-006870-f5w6fw6q 4141 7 of of IN cord-006870-f5w6fw6q 4141 8 antibiotics antibiotic NNS cord-006870-f5w6fw6q 4141 9 prior prior RB cord-006870-f5w6fw6q 4141 10 to to IN cord-006870-f5w6fw6q 4141 11 EVD EVD NNP cord-006870-f5w6fw6q 4141 12 insertion insertion NN cord-006870-f5w6fw6q 4141 13 ( ( -LRB- cord-006870-f5w6fw6q 4141 14 31/43 31/43 CD cord-006870-f5w6fw6q 4141 15 , , , cord-006870-f5w6fw6q 4141 16 72 72 CD cord-006870-f5w6fw6q 4141 17 % % NN cord-006870-f5w6fw6q 4141 18 ) ) -RRB- cord-006870-f5w6fw6q 4141 19 . . . cord-006870-f5w6fw6q 4142 1 Periprocedural periprocedural JJ cord-006870-f5w6fw6q 4142 2 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4142 3 therapy therapy NN cord-006870-f5w6fw6q 4142 4 is be VBZ cord-006870-f5w6fw6q 4142 5 the the DT cord-006870-f5w6fw6q 4142 6 most most RBS cord-006870-f5w6fw6q 4142 7 common common JJ cord-006870-f5w6fw6q 4142 8 prophylactic prophylactic JJ cord-006870-f5w6fw6q 4142 9 strategy strategy NN cord-006870-f5w6fw6q 4142 10 utilized utilize VBN cord-006870-f5w6fw6q 4142 11 by by IN cord-006870-f5w6fw6q 4142 12 respondents respondent NNS cord-006870-f5w6fw6q 4142 13 ( ( -LRB- cord-006870-f5w6fw6q 4142 14 18/43 18/43 CD cord-006870-f5w6fw6q 4142 15 , , , cord-006870-f5w6fw6q 4142 16 42 42 CD cord-006870-f5w6fw6q 4142 17 % % NN cord-006870-f5w6fw6q 4142 18 ) ) -RRB- cord-006870-f5w6fw6q 4142 19 . . . cord-006870-f5w6fw6q 4143 1 Of of IN cord-006870-f5w6fw6q 4143 2 respondents respondent NNS cord-006870-f5w6fw6q 4143 3 who who WP cord-006870-f5w6fw6q 4143 4 do do VBP cord-006870-f5w6fw6q 4143 5 not not RB cord-006870-f5w6fw6q 4143 6 continue continue VB cord-006870-f5w6fw6q 4143 7 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4143 8 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4143 9 for for IN cord-006870-f5w6fw6q 4143 10 the the DT cord-006870-f5w6fw6q 4143 11 duration duration NN cord-006870-f5w6fw6q 4143 12 of of IN cord-006870-f5w6fw6q 4143 13 EVD EVD NNP cord-006870-f5w6fw6q 4143 14 placement placement NN cord-006870-f5w6fw6q 4143 15 , , , cord-006870-f5w6fw6q 4143 16 59 59 CD cord-006870-f5w6fw6q 4143 17 % % NN cord-006870-f5w6fw6q 4143 18 ( ( -LRB- cord-006870-f5w6fw6q 4143 19 10/17 10/17 CD cord-006870-f5w6fw6q 4143 20 ) ) -RRB- cord-006870-f5w6fw6q 4143 21 utilize utilize VB cord-006870-f5w6fw6q 4143 22 antimicrobial antimicrobial NN cord-006870-f5w6fw6q 4143 23 - - HYPH cord-006870-f5w6fw6q 4143 24 impregnated impregnate VBN cord-006870-f5w6fw6q 4143 25 catheters catheter NNS cord-006870-f5w6fw6q 4143 26 to to TO cord-006870-f5w6fw6q 4143 27 reduce reduce VB cord-006870-f5w6fw6q 4143 28 incidence incidence NN cord-006870-f5w6fw6q 4143 29 of of IN cord-006870-f5w6fw6q 4143 30 VRI VRI NNP cord-006870-f5w6fw6q 4143 31 . . . cord-006870-f5w6fw6q 4144 1 The the DT cord-006870-f5w6fw6q 4144 2 importance importance NN cord-006870-f5w6fw6q 4144 3 of of IN cord-006870-f5w6fw6q 4144 4 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4144 5 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4144 6 to to TO cord-006870-f5w6fw6q 4144 7 prevent prevent VB cord-006870-f5w6fw6q 4144 8 infectious infectious JJ cord-006870-f5w6fw6q 4144 9 complications complication NNS cord-006870-f5w6fw6q 4144 10 associated associate VBN cord-006870-f5w6fw6q 4144 11 with with IN cord-006870-f5w6fw6q 4144 12 EVD EVD NNP cord-006870-f5w6fw6q 4144 13 placement placement NN cord-006870-f5w6fw6q 4144 14 is be VBZ cord-006870-f5w6fw6q 4144 15 widely widely RB cord-006870-f5w6fw6q 4144 16 accepted accept VBN cord-006870-f5w6fw6q 4144 17 . . . cord-006870-f5w6fw6q 4145 1 Prophylactic prophylactic JJ cord-006870-f5w6fw6q 4145 2 strategies strategy NNS cord-006870-f5w6fw6q 4145 3 vary vary VBP cord-006870-f5w6fw6q 4145 4 between between IN cord-006870-f5w6fw6q 4145 5 institutions institution NNS cord-006870-f5w6fw6q 4145 6 . . . cord-006870-f5w6fw6q 4146 1 Periprocedural periprocedural JJ cord-006870-f5w6fw6q 4146 2 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4146 3 therapy therapy NN cord-006870-f5w6fw6q 4146 4 is be VBZ cord-006870-f5w6fw6q 4146 5 the the DT cord-006870-f5w6fw6q 4146 6 most most RBS cord-006870-f5w6fw6q 4146 7 common common JJ cord-006870-f5w6fw6q 4146 8 prophylactic prophylactic JJ cord-006870-f5w6fw6q 4146 9 strategy strategy NN cord-006870-f5w6fw6q 4146 10 utilized utilize VBN cord-006870-f5w6fw6q 4146 11 by by IN cord-006870-f5w6fw6q 4146 12 survey survey NN cord-006870-f5w6fw6q 4146 13 respondents respondent NNS cord-006870-f5w6fw6q 4146 14 . . . cord-006870-f5w6fw6q 4147 1 Antimicrobial Antimicrobial NNP cord-006870-f5w6fw6q 4147 2 - - HYPH cord-006870-f5w6fw6q 4147 3 impregnated impregnate VBN cord-006870-f5w6fw6q 4147 4 catheters catheter NNS cord-006870-f5w6fw6q 4147 5 are be VBP cord-006870-f5w6fw6q 4147 6 commonly commonly RB cord-006870-f5w6fw6q 4147 7 utilized utilize VBN cord-006870-f5w6fw6q 4147 8 in in IN cord-006870-f5w6fw6q 4147 9 institutions institution NNS cord-006870-f5w6fw6q 4147 10 using use VBG cord-006870-f5w6fw6q 4147 11 periprocedural periprocedural JJ cord-006870-f5w6fw6q 4147 12 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 4147 13 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 4147 14 . . . cord-006870-f5w6fw6q 4148 1 The the DT cord-006870-f5w6fw6q 4148 2 postoperative postoperative JJ cord-006870-f5w6fw6q 4148 3 course course NN cord-006870-f5w6fw6q 4148 4 seen see VBN cord-006870-f5w6fw6q 4148 5 in in IN cord-006870-f5w6fw6q 4148 6 critically critically RB cord-006870-f5w6fw6q 4148 7 ill ill JJ cord-006870-f5w6fw6q 4148 8 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 4148 9 patients patient NNS cord-006870-f5w6fw6q 4148 10 is be VBZ cord-006870-f5w6fw6q 4148 11 known know VBN cord-006870-f5w6fw6q 4148 12 to to TO cord-006870-f5w6fw6q 4148 13 vary vary VB cord-006870-f5w6fw6q 4148 14 depending depend VBG cord-006870-f5w6fw6q 4148 15 on on IN cord-006870-f5w6fw6q 4148 16 the the DT cord-006870-f5w6fw6q 4148 17 timing timing NN cord-006870-f5w6fw6q 4148 18 of of IN cord-006870-f5w6fw6q 4148 19 the the DT cord-006870-f5w6fw6q 4148 20 surgical surgical JJ cord-006870-f5w6fw6q 4148 21 procedure procedure NN cord-006870-f5w6fw6q 4148 22 . . . cord-006870-f5w6fw6q 4149 1 This this DT cord-006870-f5w6fw6q 4149 2 study study NN cord-006870-f5w6fw6q 4149 3 seeks seek VBZ cord-006870-f5w6fw6q 4149 4 to to TO cord-006870-f5w6fw6q 4149 5 compare compare VB cord-006870-f5w6fw6q 4149 6 the the DT cord-006870-f5w6fw6q 4149 7 clinical clinical JJ cord-006870-f5w6fw6q 4149 8 characteristics characteristic NNS cord-006870-f5w6fw6q 4149 9 , , , cord-006870-f5w6fw6q 4149 10 complications complication NNS cord-006870-f5w6fw6q 4149 11 , , , cord-006870-f5w6fw6q 4149 12 and and CC cord-006870-f5w6fw6q 4149 13 outcomes outcome NNS cord-006870-f5w6fw6q 4149 14 between between IN cord-006870-f5w6fw6q 4149 15 elective elective JJ cord-006870-f5w6fw6q 4149 16 or or CC cord-006870-f5w6fw6q 4149 17 urgent urgent JJ cord-006870-f5w6fw6q 4149 18 surgery surgery NN cord-006870-f5w6fw6q 4149 19 patients patient NNS cord-006870-f5w6fw6q 4149 20 admitted admit VBN cord-006870-f5w6fw6q 4149 21 to to IN cord-006870-f5w6fw6q 4149 22 the the DT cord-006870-f5w6fw6q 4149 23 intensive intensive JJ cord-006870-f5w6fw6q 4149 24 care care NN cord-006870-f5w6fw6q 4149 25 unit unit NN cord-006870-f5w6fw6q 4149 26 ( ( -LRB- cord-006870-f5w6fw6q 4149 27 ICU ICU NNP cord-006870-f5w6fw6q 4149 28 ) ) -RRB- cord-006870-f5w6fw6q 4149 29 . . . cord-006870-f5w6fw6q 4150 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 4150 2 review review NN cord-006870-f5w6fw6q 4150 3 of of IN cord-006870-f5w6fw6q 4150 4 a a DT cord-006870-f5w6fw6q 4150 5 two two CD cord-006870-f5w6fw6q 4150 6 - - HYPH cord-006870-f5w6fw6q 4150 7 year year NN cord-006870-f5w6fw6q 4150 8 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 4150 9 patients patient NNS cord-006870-f5w6fw6q 4150 10 ' ' POS cord-006870-f5w6fw6q 4150 11 cohort cohort NN cord-006870-f5w6fw6q 4150 12 . . . cord-006870-f5w6fw6q 4151 1 The the DT cord-006870-f5w6fw6q 4151 2 pre pre JJ cord-006870-f5w6fw6q 4151 3 and and CC cord-006870-f5w6fw6q 4151 4 postoperative postoperative JJ cord-006870-f5w6fw6q 4151 5 conditions condition NNS cord-006870-f5w6fw6q 4151 6 and and CC cord-006870-f5w6fw6q 4151 7 outcomes outcome NNS cord-006870-f5w6fw6q 4151 8 were be VBD cord-006870-f5w6fw6q 4151 9 compared compare VBN cord-006870-f5w6fw6q 4151 10 between between IN cord-006870-f5w6fw6q 4151 11 elective elective JJ cord-006870-f5w6fw6q 4151 12 ( ( -LRB- cord-006870-f5w6fw6q 4151 13 group group NN cord-006870-f5w6fw6q 4151 14 A A NNP cord-006870-f5w6fw6q 4151 15 ) ) -RRB- cord-006870-f5w6fw6q 4151 16 and and CC cord-006870-f5w6fw6q 4151 17 emergency emergency NN cord-006870-f5w6fw6q 4151 18 ( ( -LRB- cord-006870-f5w6fw6q 4151 19 group group NN cord-006870-f5w6fw6q 4151 20 B b NN cord-006870-f5w6fw6q 4151 21 ) ) -RRB- cord-006870-f5w6fw6q 4151 22 surgery surgery NN cord-006870-f5w6fw6q 4151 23 patients patient NNS cord-006870-f5w6fw6q 4151 24 . . . cord-006870-f5w6fw6q 4152 1 A a DT cord-006870-f5w6fw6q 4152 2 total total NN cord-006870-f5w6fw6q 4152 3 of of IN cord-006870-f5w6fw6q 4152 4 416 416 CD cord-006870-f5w6fw6q 4152 5 patients patient NNS cord-006870-f5w6fw6q 4152 6 were be VBD cord-006870-f5w6fw6q 4152 7 evaluated evaluate VBN cord-006870-f5w6fw6q 4152 8 , , , cord-006870-f5w6fw6q 4152 9 262 262 CD cord-006870-f5w6fw6q 4152 10 in in IN cord-006870-f5w6fw6q 4152 11 Group Group NNP cord-006870-f5w6fw6q 4152 12 A A NNP cord-006870-f5w6fw6q 4152 13 and and CC cord-006870-f5w6fw6q 4152 14 154 154 CD cord-006870-f5w6fw6q 4152 15 in in IN cord-006870-f5w6fw6q 4152 16 Group Group NNP cord-006870-f5w6fw6q 4152 17 B. B. NNP cord-006870-f5w6fw6q 4153 1 The the DT cord-006870-f5w6fw6q 4153 2 most most RBS cord-006870-f5w6fw6q 4153 3 common common JJ cord-006870-f5w6fw6q 4153 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 4153 5 was be VBD cord-006870-f5w6fw6q 4153 6 intracranial intracranial JJ cord-006870-f5w6fw6q 4153 7 tumor tumor NN cord-006870-f5w6fw6q 4153 8 . . . cord-006870-f5w6fw6q 4154 1 The the DT cord-006870-f5w6fw6q 4154 2 mean mean JJ cord-006870-f5w6fw6q 4154 3 American American NNP cord-006870-f5w6fw6q 4154 4 Society Society NNP cord-006870-f5w6fw6q 4154 5 of of IN cord-006870-f5w6fw6q 4154 6 Anesthesiology Anesthesiology NNP cord-006870-f5w6fw6q 4154 7 ( ( -LRB- cord-006870-f5w6fw6q 4154 8 ASA ASA NNP cord-006870-f5w6fw6q 4154 9 ) ) -RRB- cord-006870-f5w6fw6q 4154 10 score score NN cord-006870-f5w6fw6q 4154 11 was be VBD cord-006870-f5w6fw6q 4154 12 significantly significantly RB cord-006870-f5w6fw6q 4154 13 higher high JJR cord-006870-f5w6fw6q 4154 14 in in IN cord-006870-f5w6fw6q 4154 15 Group Group NNP cord-006870-f5w6fw6q 4154 16 B B NNP cord-006870-f5w6fw6q 4154 17 than than IN cord-006870-f5w6fw6q 4154 18 in in IN cord-006870-f5w6fw6q 4154 19 group group NN cord-006870-f5w6fw6q 4154 20 A a NN cord-006870-f5w6fw6q 4154 21 ( ( -LRB- cord-006870-f5w6fw6q 4154 22 3.35 3.35 CD cord-006870-f5w6fw6q 4154 23 vs. vs. IN cord-006870-f5w6fw6q 4154 24 2.79 2.79 CD cord-006870-f5w6fw6q 4154 25 , , , cord-006870-f5w6fw6q 4154 26 p<0.05 p<0.05 CD cord-006870-f5w6fw6q 4154 27 ) ) -RRB- cord-006870-f5w6fw6q 4154 28 . . . cord-006870-f5w6fw6q 4155 1 Mean mean JJ cord-006870-f5w6fw6q 4155 2 Sequential Sequential NNP cord-006870-f5w6fw6q 4155 3 Organ Organ NNP cord-006870-f5w6fw6q 4155 4 Failure Failure NNP cord-006870-f5w6fw6q 4155 5 Assessment Assessment NNP cord-006870-f5w6fw6q 4155 6 ( ( -LRB- cord-006870-f5w6fw6q 4155 7 SOFA SOFA NNP cord-006870-f5w6fw6q 4155 8 ) ) -RRB- cord-006870-f5w6fw6q 4155 9 score score NN cord-006870-f5w6fw6q 4155 10 on on IN cord-006870-f5w6fw6q 4155 11 admission admission NN cord-006870-f5w6fw6q 4155 12 was be VBD cord-006870-f5w6fw6q 4155 13 higher high JJR cord-006870-f5w6fw6q 4155 14 in in IN cord-006870-f5w6fw6q 4155 15 Group Group NNP cord-006870-f5w6fw6q 4155 16 B B NNP cord-006870-f5w6fw6q 4155 17 ( ( -LRB- cord-006870-f5w6fw6q 4155 18 2.47 2.47 CD cord-006870-f5w6fw6q 4155 19 vs. vs. IN cord-006870-f5w6fw6q 4155 20 0.83 0.83 CD cord-006870-f5w6fw6q 4155 21 , , , cord-006870-f5w6fw6q 4155 22 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4155 23 ) ) -RRB- cord-006870-f5w6fw6q 4155 24 . . . cord-006870-f5w6fw6q 4156 1 These these DT cord-006870-f5w6fw6q 4156 2 patients patient NNS cord-006870-f5w6fw6q 4156 3 were be VBD cord-006870-f5w6fw6q 4156 4 more more RBR cord-006870-f5w6fw6q 4156 5 likely likely JJ cord-006870-f5w6fw6q 4156 6 to to TO cord-006870-f5w6fw6q 4156 7 require require VB cord-006870-f5w6fw6q 4156 8 mechanical mechanical JJ cord-006870-f5w6fw6q 4156 9 ventilation ventilation NN cord-006870-f5w6fw6q 4156 10 ( ( -LRB- cord-006870-f5w6fw6q 4156 11 OR or CC cord-006870-f5w6fw6q 4156 12 14.75 14.75 CD cord-006870-f5w6fw6q 4156 13 , , , cord-006870-f5w6fw6q 4156 14 p<0 p<0 NNP cord-006870-f5w6fw6q 4156 15 .001 .001 CD cord-006870-f5w6fw6q 4156 16 ) ) -RRB- cord-006870-f5w6fw6q 4156 17 and and CC cord-006870-f5w6fw6q 4156 18 vasopressors vasopressor NNS cord-006870-f5w6fw6q 4156 19 ( ( -LRB- cord-006870-f5w6fw6q 4156 20 OR or CC cord-006870-f5w6fw6q 4156 21 5.76 5.76 CD cord-006870-f5w6fw6q 4156 22 , , , cord-006870-f5w6fw6q 4156 23 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4156 24 ) ) -RRB- cord-006870-f5w6fw6q 4156 25 . . . cord-006870-f5w6fw6q 4157 1 Group Group NNP cord-006870-f5w6fw6q 4157 2 B B NNP cord-006870-f5w6fw6q 4157 3 had have VBD cord-006870-f5w6fw6q 4157 4 a a DT cord-006870-f5w6fw6q 4157 5 higher high JJR cord-006870-f5w6fw6q 4157 6 probability probability NN cord-006870-f5w6fw6q 4157 7 of of IN cord-006870-f5w6fw6q 4157 8 rebleeding rebleeding NN cord-006870-f5w6fw6q 4157 9 ( ( -LRB- cord-006870-f5w6fw6q 4157 10 OR or CC cord-006870-f5w6fw6q 4157 11 5.29 5.29 CD cord-006870-f5w6fw6q 4157 12 , , , cord-006870-f5w6fw6q 4157 13 p<0 p<0 NNP cord-006870-f5w6fw6q 4157 14 .001 .001 CD cord-006870-f5w6fw6q 4157 15 ) ) -RRB- cord-006870-f5w6fw6q 4157 16 , , , cord-006870-f5w6fw6q 4157 17 intracranial intracranial JJ cord-006870-f5w6fw6q 4157 18 hypertension hypertension NN cord-006870-f5w6fw6q 4157 19 ( ( -LRB- cord-006870-f5w6fw6q 4157 20 OR OR NNP cord-006870-f5w6fw6q 4157 21 11.9 11.9 CD cord-006870-f5w6fw6q 4157 22 , , , cord-006870-f5w6fw6q 4157 23 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4157 24 ) ) -RRB- cord-006870-f5w6fw6q 4157 25 , , , cord-006870-f5w6fw6q 4157 26 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 4157 27 ( ( -LRB- cord-006870-f5w6fw6q 4157 28 OR or CC cord-006870-f5w6fw6q 4157 29 6.45 6.45 CD cord-006870-f5w6fw6q 4157 30 , , , cord-006870-f5w6fw6q 4157 31 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4157 32 ) ) -RRB- cord-006870-f5w6fw6q 4157 33 , , , cord-006870-f5w6fw6q 4157 34 and and CC cord-006870-f5w6fw6q 4157 35 reintervention reintervention NN cord-006870-f5w6fw6q 4157 36 ( ( -LRB- cord-006870-f5w6fw6q 4157 37 OR or CC cord-006870-f5w6fw6q 4157 38 1.91 1.91 CD cord-006870-f5w6fw6q 4157 39 , , , cord-006870-f5w6fw6q 4157 40 p=0.043 p=0.043 NNP cord-006870-f5w6fw6q 4157 41 ) ) -RRB- cord-006870-f5w6fw6q 4157 42 . . . cord-006870-f5w6fw6q 4158 1 Post post JJ cord-006870-f5w6fw6q 4158 2 - - JJ cord-006870-f5w6fw6q 4158 3 operative operative JJ cord-006870-f5w6fw6q 4158 4 nausea nausea NN cord-006870-f5w6fw6q 4158 5 and and CC cord-006870-f5w6fw6q 4158 6 vomiting vomiting NN cord-006870-f5w6fw6q 4158 7 were be VBD cord-006870-f5w6fw6q 4158 8 less less RBR cord-006870-f5w6fw6q 4158 9 likely likely JJ cord-006870-f5w6fw6q 4158 10 in in IN cord-006870-f5w6fw6q 4158 11 group group NN cord-006870-f5w6fw6q 4158 12 B b NN cord-006870-f5w6fw6q 4158 13 ( ( -LRB- cord-006870-f5w6fw6q 4158 14 1.9 1.9 CD cord-006870-f5w6fw6q 4158 15 % % NN cord-006870-f5w6fw6q 4158 16 vs. vs. CC cord-006870-f5w6fw6q 4158 17 9.9 9.9 CD cord-006870-f5w6fw6q 4158 18 % % NN cord-006870-f5w6fw6q 4158 19 and and CC cord-006870-f5w6fw6q 4158 20 0 0 CD cord-006870-f5w6fw6q 4158 21 vs. vs. NN cord-006870-f5w6fw6q 4158 22 3.4 3.4 CD cord-006870-f5w6fw6q 4158 23 % % NN cord-006870-f5w6fw6q 4158 24 , , , cord-006870-f5w6fw6q 4158 25 respectively respectively RB cord-006870-f5w6fw6q 4158 26 ) ) -RRB- cord-006870-f5w6fw6q 4158 27 . . . cord-006870-f5w6fw6q 4159 1 Mean mean JJ cord-006870-f5w6fw6q 4159 2 hospital hospital NN cord-006870-f5w6fw6q 4159 3 and and CC cord-006870-f5w6fw6q 4159 4 ICU ICU NNP cord-006870-f5w6fw6q 4159 5 LOS LOS NNP cord-006870-f5w6fw6q 4159 6 were be VBD cord-006870-f5w6fw6q 4159 7 shorter short JJR cord-006870-f5w6fw6q 4159 8 in in IN cord-006870-f5w6fw6q 4159 9 group group NN cord-006870-f5w6fw6q 4159 10 A a NN cord-006870-f5w6fw6q 4159 11 than than IN cord-006870-f5w6fw6q 4159 12 in in IN cord-006870-f5w6fw6q 4159 13 group group NN cord-006870-f5w6fw6q 4159 14 B b NN cord-006870-f5w6fw6q 4159 15 ( ( -LRB- cord-006870-f5w6fw6q 4159 16 9.1 9.1 CD cord-006870-f5w6fw6q 4159 17 vs. vs. NN cord-006870-f5w6fw6q 4159 18 15.4 15.4 CD cord-006870-f5w6fw6q 4159 19 and and CC cord-006870-f5w6fw6q 4159 20 2.8 2.8 CD cord-006870-f5w6fw6q 4159 21 vs. vs. IN cord-006870-f5w6fw6q 4159 22 5.7 5.7 CD cord-006870-f5w6fw6q 4159 23 , , , cord-006870-f5w6fw6q 4159 24 p<0.001 p<0.001 JJ cord-006870-f5w6fw6q 4159 25 respectively respectively RB cord-006870-f5w6fw6q 4159 26 ) ) -RRB- cord-006870-f5w6fw6q 4159 27 . . . cord-006870-f5w6fw6q 4160 1 Mortality mortality NN cord-006870-f5w6fw6q 4160 2 rate rate NN cord-006870-f5w6fw6q 4160 3 during during IN cord-006870-f5w6fw6q 4160 4 ICU ICU NNP cord-006870-f5w6fw6q 4160 5 stay stay NN cord-006870-f5w6fw6q 4160 6 was be VBD cord-006870-f5w6fw6q 4160 7 higher high JJR cord-006870-f5w6fw6q 4160 8 in in IN cord-006870-f5w6fw6q 4160 9 Group Group NNP cord-006870-f5w6fw6q 4160 10 B B NNP cord-006870-f5w6fw6q 4160 11 ( ( -LRB- cord-006870-f5w6fw6q 4160 12 9.74 9.74 CD cord-006870-f5w6fw6q 4160 13 % % NN cord-006870-f5w6fw6q 4160 14 vs. vs. IN cord-006870-f5w6fw6q 4160 15 1.52 1.52 CD cord-006870-f5w6fw6q 4160 16 % % NN cord-006870-f5w6fw6q 4160 17 ; ; : cord-006870-f5w6fw6q 4160 18 OR or CC cord-006870-f5w6fw6q 4160 19 6.96 6.96 CD cord-006870-f5w6fw6q 4160 20 , , , cord-006870-f5w6fw6q 4160 21 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4160 22 ) ) -RRB- cord-006870-f5w6fw6q 4160 23 . . . cord-006870-f5w6fw6q 4161 1 The the DT cord-006870-f5w6fw6q 4161 2 preoperative preoperative JJ cord-006870-f5w6fw6q 4161 3 Glasgow Glasgow NNP cord-006870-f5w6fw6q 4161 4 Coma Coma NNP cord-006870-f5w6fw6q 4161 5 Scale Scale NNP cord-006870-f5w6fw6q 4161 6 ( ( -LRB- cord-006870-f5w6fw6q 4161 7 GCS GCS NNP cord-006870-f5w6fw6q 4161 8 ) ) -RRB- cord-006870-f5w6fw6q 4161 9 in in IN cord-006870-f5w6fw6q 4161 10 patients patient NNS cord-006870-f5w6fw6q 4161 11 who who WP cord-006870-f5w6fw6q 4161 12 died die VBD cord-006870-f5w6fw6q 4161 13 , , , cord-006870-f5w6fw6q 4161 14 was be VBD cord-006870-f5w6fw6q 4161 15 below below IN cord-006870-f5w6fw6q 4161 16 8 8 CD cord-006870-f5w6fw6q 4161 17 in in IN cord-006870-f5w6fw6q 4161 18 only only RB cord-006870-f5w6fw6q 4161 19 a a DT cord-006870-f5w6fw6q 4161 20 minority minority NN cord-006870-f5w6fw6q 4161 21 of of IN cord-006870-f5w6fw6q 4161 22 them -PRON- PRP cord-006870-f5w6fw6q 4161 23 ( ( -LRB- cord-006870-f5w6fw6q 4161 24 14.28 14.28 CD cord-006870-f5w6fw6q 4161 25 % % NN cord-006870-f5w6fw6q 4161 26 in in IN cord-006870-f5w6fw6q 4161 27 Group Group NNP cord-006870-f5w6fw6q 4161 28 B B NNP cord-006870-f5w6fw6q 4161 29 ; ; : cord-006870-f5w6fw6q 4161 30 0 0 CD cord-006870-f5w6fw6q 4161 31 % % NN cord-006870-f5w6fw6q 4161 32 in in IN cord-006870-f5w6fw6q 4161 33 Group Group NNP cord-006870-f5w6fw6q 4161 34 A A NNP cord-006870-f5w6fw6q 4161 35 ) ) -RRB- cord-006870-f5w6fw6q 4161 36 . . . cord-006870-f5w6fw6q 4162 1 In in IN cord-006870-f5w6fw6q 4162 2 this this DT cord-006870-f5w6fw6q 4162 3 cohort cohort NN cord-006870-f5w6fw6q 4162 4 of of IN cord-006870-f5w6fw6q 4162 5 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 4162 6 patients patient NNS cord-006870-f5w6fw6q 4162 7 , , , cord-006870-f5w6fw6q 4162 8 emergency emergency NN cord-006870-f5w6fw6q 4162 9 , , , cord-006870-f5w6fw6q 4162 10 compared compare VBN cord-006870-f5w6fw6q 4162 11 to to IN cord-006870-f5w6fw6q 4162 12 elective elective JJ cord-006870-f5w6fw6q 4162 13 operations operation NNS cord-006870-f5w6fw6q 4162 14 , , , cord-006870-f5w6fw6q 4162 15 were be VBD cord-006870-f5w6fw6q 4162 16 associated associate VBN cord-006870-f5w6fw6q 4162 17 with with IN cord-006870-f5w6fw6q 4162 18 higher high JJR cord-006870-f5w6fw6q 4162 19 post post JJ cord-006870-f5w6fw6q 4162 20 - - JJ cord-006870-f5w6fw6q 4162 21 operative operative JJ cord-006870-f5w6fw6q 4162 22 complications complication NNS cord-006870-f5w6fw6q 4162 23 and and CC cord-006870-f5w6fw6q 4162 24 mortality mortality NN cord-006870-f5w6fw6q 4162 25 rates rate NNS cord-006870-f5w6fw6q 4162 26 . . . cord-006870-f5w6fw6q 4163 1 Emergency emergency NN cord-006870-f5w6fw6q 4163 2 surgery surgery NN cord-006870-f5w6fw6q 4163 3 was be VBD cord-006870-f5w6fw6q 4163 4 associated associate VBN cord-006870-f5w6fw6q 4163 5 with with IN cord-006870-f5w6fw6q 4163 6 a a DT cord-006870-f5w6fw6q 4163 7 higher high JJR cord-006870-f5w6fw6q 4163 8 severity severity NN cord-006870-f5w6fw6q 4163 9 of of IN cord-006870-f5w6fw6q 4163 10 illness illness NN cord-006870-f5w6fw6q 4163 11 measured measure VBN cord-006870-f5w6fw6q 4163 12 by by IN cord-006870-f5w6fw6q 4163 13 the the DT cord-006870-f5w6fw6q 4163 14 SOFA SOFA NNP cord-006870-f5w6fw6q 4163 15 and and CC cord-006870-f5w6fw6q 4163 16 ASA ASA NNP cord-006870-f5w6fw6q 4163 17 scores score NNS cord-006870-f5w6fw6q 4163 18 . . . cord-006870-f5w6fw6q 4164 1 Intraprocedure intraprocedure JJ cord-006870-f5w6fw6q 4164 2 rupture rupture NN cord-006870-f5w6fw6q 4164 3 ( ( -LRB- cord-006870-f5w6fw6q 4164 4 IPR IPR NNP cord-006870-f5w6fw6q 4164 5 ) ) -RRB- cord-006870-f5w6fw6q 4164 6 is be VBZ cord-006870-f5w6fw6q 4164 7 a a DT cord-006870-f5w6fw6q 4164 8 rare rare JJ cord-006870-f5w6fw6q 4164 9 but but CC cord-006870-f5w6fw6q 4164 10 potentially potentially RB cord-006870-f5w6fw6q 4164 11 serious serious JJ cord-006870-f5w6fw6q 4164 12 complication complication NN cord-006870-f5w6fw6q 4164 13 of of IN cord-006870-f5w6fw6q 4164 14 endovascular endovascular JJ cord-006870-f5w6fw6q 4164 15 coiling coiling NN cord-006870-f5w6fw6q 4164 16 of of IN cord-006870-f5w6fw6q 4164 17 intracranial intracranial JJ cord-006870-f5w6fw6q 4164 18 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4164 19 . . . cord-006870-f5w6fw6q 4165 1 Potential potential JJ cord-006870-f5w6fw6q 4165 2 complications complication NNS cord-006870-f5w6fw6q 4165 3 include include VBP cord-006870-f5w6fw6q 4165 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4165 5 , , , cord-006870-f5w6fw6q 4165 6 ischemic ischemic JJ cord-006870-f5w6fw6q 4165 7 stroke stroke NN cord-006870-f5w6fw6q 4165 8 , , , cord-006870-f5w6fw6q 4165 9 vasospasm vasospasm NN cord-006870-f5w6fw6q 4165 10 and and CC cord-006870-f5w6fw6q 4165 11 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 4165 12 which which WDT cord-006870-f5w6fw6q 4165 13 can can MD cord-006870-f5w6fw6q 4165 14 lead lead VB cord-006870-f5w6fw6q 4165 15 to to IN cord-006870-f5w6fw6q 4165 16 increased increase VBN cord-006870-f5w6fw6q 4165 17 morbidity morbidity NN cord-006870-f5w6fw6q 4165 18 and and CC cord-006870-f5w6fw6q 4165 19 mortality mortality NN cord-006870-f5w6fw6q 4165 20 . . . cord-006870-f5w6fw6q 4166 1 The the DT cord-006870-f5w6fw6q 4166 2 clinical clinical JJ cord-006870-f5w6fw6q 4166 3 course course NN cord-006870-f5w6fw6q 4166 4 for for IN cord-006870-f5w6fw6q 4166 5 these these DT cord-006870-f5w6fw6q 4166 6 patients patient NNS cord-006870-f5w6fw6q 4166 7 is be VBZ cord-006870-f5w6fw6q 4166 8 not not RB cord-006870-f5w6fw6q 4166 9 well well RB cord-006870-f5w6fw6q 4166 10 studied study VBN cord-006870-f5w6fw6q 4166 11 and and CC cord-006870-f5w6fw6q 4166 12 characterized characterize VBD cord-006870-f5w6fw6q 4166 13 . . . cord-006870-f5w6fw6q 4167 1 We -PRON- PRP cord-006870-f5w6fw6q 4167 2 performed perform VBD cord-006870-f5w6fw6q 4167 3 a a DT cord-006870-f5w6fw6q 4167 4 retrospective retrospective JJ cord-006870-f5w6fw6q 4167 5 review review NN cord-006870-f5w6fw6q 4167 6 of of IN cord-006870-f5w6fw6q 4167 7 prospectively prospectively RB cord-006870-f5w6fw6q 4167 8 collected collect VBN cord-006870-f5w6fw6q 4167 9 data datum NNS cord-006870-f5w6fw6q 4167 10 for for IN cord-006870-f5w6fw6q 4167 11 all all DT cord-006870-f5w6fw6q 4167 12 unruptured unruptured JJ cord-006870-f5w6fw6q 4167 13 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4167 14 treated treat VBN cord-006870-f5w6fw6q 4167 15 with with IN cord-006870-f5w6fw6q 4167 16 endovascular endovascular JJ cord-006870-f5w6fw6q 4167 17 coil coil NN cord-006870-f5w6fw6q 4167 18 embolization embolization NN cord-006870-f5w6fw6q 4167 19 between between IN cord-006870-f5w6fw6q 4167 20 July July NNP cord-006870-f5w6fw6q 4167 21 2003 2003 CD cord-006870-f5w6fw6q 4167 22 and and CC cord-006870-f5w6fw6q 4167 23 March March NNP cord-006870-f5w6fw6q 4167 24 2017 2017 CD cord-006870-f5w6fw6q 4167 25 at at IN cord-006870-f5w6fw6q 4167 26 a a DT cord-006870-f5w6fw6q 4167 27 large large JJ cord-006870-f5w6fw6q 4167 28 universitybased universitybased JJ cord-006870-f5w6fw6q 4167 29 hospital hospital NN cord-006870-f5w6fw6q 4167 30 . . . cord-006870-f5w6fw6q 4168 1 Out out IN cord-006870-f5w6fw6q 4168 2 of of IN cord-006870-f5w6fw6q 4168 3 998 998 CD cord-006870-f5w6fw6q 4168 4 cases case NNS cord-006870-f5w6fw6q 4168 5 of of IN cord-006870-f5w6fw6q 4168 6 all all DT cord-006870-f5w6fw6q 4168 7 unruptured unruptured JJ cord-006870-f5w6fw6q 4168 8 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4168 9 coil coil NN cord-006870-f5w6fw6q 4168 10 embolizations embolization NNS cord-006870-f5w6fw6q 4168 11 , , , cord-006870-f5w6fw6q 4168 12 10 10 CD cord-006870-f5w6fw6q 4168 13 ( ( -LRB- cord-006870-f5w6fw6q 4168 14 1.002 1.002 CD cord-006870-f5w6fw6q 4168 15 % % NN cord-006870-f5w6fw6q 4168 16 ) ) -RRB- cord-006870-f5w6fw6q 4168 17 patients patient NNS cord-006870-f5w6fw6q 4168 18 had have VBD cord-006870-f5w6fw6q 4168 19 IPR IPR NNP cord-006870-f5w6fw6q 4168 20 . . . cord-006870-f5w6fw6q 4169 1 We -PRON- PRP cord-006870-f5w6fw6q 4169 2 reviewed review VBD cord-006870-f5w6fw6q 4169 3 baseline baseline JJ cord-006870-f5w6fw6q 4169 4 data datum NNS cord-006870-f5w6fw6q 4169 5 , , , cord-006870-f5w6fw6q 4169 6 procedure procedure NN cord-006870-f5w6fw6q 4169 7 notes note NNS cord-006870-f5w6fw6q 4169 8 , , , cord-006870-f5w6fw6q 4169 9 clinical clinical JJ cord-006870-f5w6fw6q 4169 10 course course NN cord-006870-f5w6fw6q 4169 11 , , , cord-006870-f5w6fw6q 4169 12 and and CC cord-006870-f5w6fw6q 4169 13 outcomes outcome NNS cord-006870-f5w6fw6q 4169 14 at at IN cord-006870-f5w6fw6q 4169 15 discharge discharge NN cord-006870-f5w6fw6q 4169 16 and and CC cord-006870-f5w6fw6q 4169 17 at at IN cord-006870-f5w6fw6q 4169 18 3 3 CD cord-006870-f5w6fw6q 4169 19 , , , cord-006870-f5w6fw6q 4169 20 6 6 CD cord-006870-f5w6fw6q 4169 21 and and CC cord-006870-f5w6fw6q 4169 22 12 12 CD cord-006870-f5w6fw6q 4169 23 months month NNS cord-006870-f5w6fw6q 4169 24 . . . cord-006870-f5w6fw6q 4170 1 Among among IN cord-006870-f5w6fw6q 4170 2 the the DT cord-006870-f5w6fw6q 4170 3 ten ten CD cord-006870-f5w6fw6q 4170 4 patients patient NNS cord-006870-f5w6fw6q 4170 5 , , , cord-006870-f5w6fw6q 4170 6 the the DT cord-006870-f5w6fw6q 4170 7 location location NN cord-006870-f5w6fw6q 4170 8 of of IN cord-006870-f5w6fw6q 4170 9 the the DT cord-006870-f5w6fw6q 4170 10 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4170 11 included include VBD cord-006870-f5w6fw6q 4170 12 : : : cord-006870-f5w6fw6q 4170 13 4 4 CD cord-006870-f5w6fw6q 4170 14 basilar basilar NNP cord-006870-f5w6fw6q 4170 15 apex apex NN cord-006870-f5w6fw6q 4170 16 , , , cord-006870-f5w6fw6q 4170 17 3 3 CD cord-006870-f5w6fw6q 4170 18 internal internal JJ cord-006870-f5w6fw6q 4170 19 carotid carotid JJ cord-006870-f5w6fw6q 4170 20 artery artery NN cord-006870-f5w6fw6q 4170 21 1 1 CD cord-006870-f5w6fw6q 4170 22 anterior anterior JJ cord-006870-f5w6fw6q 4170 23 communicating communicate VBG cord-006870-f5w6fw6q 4170 24 artery artery NN cord-006870-f5w6fw6q 4170 25 , , , cord-006870-f5w6fw6q 4170 26 1 1 CD cord-006870-f5w6fw6q 4170 27 posterior posterior JJ cord-006870-f5w6fw6q 4170 28 cerebral cerebral JJ cord-006870-f5w6fw6q 4170 29 artery artery NN cord-006870-f5w6fw6q 4170 30 , , , cord-006870-f5w6fw6q 4170 31 and and CC cord-006870-f5w6fw6q 4170 32 1 1 CD cord-006870-f5w6fw6q 4170 33 posterior posterior JJ cord-006870-f5w6fw6q 4170 34 communicating communicate VBG cord-006870-f5w6fw6q 4170 35 artery artery NN cord-006870-f5w6fw6q 4170 36 aneurysm aneurysm NN cord-006870-f5w6fw6q 4170 37 . . . cord-006870-f5w6fw6q 4171 1 Patients patient NNS cord-006870-f5w6fw6q 4171 2 were be VBD cord-006870-f5w6fw6q 4171 3 monitored monitor VBN cord-006870-f5w6fw6q 4171 4 in in IN cord-006870-f5w6fw6q 4171 5 the the DT cord-006870-f5w6fw6q 4171 6 ICU ICU NNP cord-006870-f5w6fw6q 4171 7 for for IN cord-006870-f5w6fw6q 4171 8 variable variable JJ cord-006870-f5w6fw6q 4171 9 lengths length NNS cord-006870-f5w6fw6q 4171 10 of of IN cord-006870-f5w6fw6q 4171 11 time time NN cord-006870-f5w6fw6q 4171 12 and and CC cord-006870-f5w6fw6q 4171 13 daily daily JJ cord-006870-f5w6fw6q 4171 14 transcranial transcranial JJ cord-006870-f5w6fw6q 4171 15 Doppler Doppler NNP cord-006870-f5w6fw6q 4171 16 ultrasound ultrasound NN cord-006870-f5w6fw6q 4171 17 detected detect VBD cord-006870-f5w6fw6q 4171 18 no no DT cord-006870-f5w6fw6q 4171 19 significant significant JJ cord-006870-f5w6fw6q 4171 20 sonographic sonographic JJ cord-006870-f5w6fw6q 4171 21 vasospasm vasospasm NN cord-006870-f5w6fw6q 4171 22 . . . cord-006870-f5w6fw6q 4172 1 The the DT cord-006870-f5w6fw6q 4172 2 large large JJ cord-006870-f5w6fw6q 4172 3 majority majority NN cord-006870-f5w6fw6q 4172 4 of of IN cord-006870-f5w6fw6q 4172 5 the the DT cord-006870-f5w6fw6q 4172 6 patients patient NNS cord-006870-f5w6fw6q 4172 7 ( ( -LRB- cord-006870-f5w6fw6q 4172 8 8/10 8/10 CD cord-006870-f5w6fw6q 4172 9 ) ) -RRB- cord-006870-f5w6fw6q 4172 10 were be VBD cord-006870-f5w6fw6q 4172 11 discharged discharge VBN cord-006870-f5w6fw6q 4172 12 to to IN cord-006870-f5w6fw6q 4172 13 home home NN cord-006870-f5w6fw6q 4172 14 at at IN cord-006870-f5w6fw6q 4172 15 their -PRON- PRP$ cord-006870-f5w6fw6q 4172 16 baseline baseline JJ cord-006870-f5w6fw6q 4172 17 functional functional JJ cord-006870-f5w6fw6q 4172 18 status status NN cord-006870-f5w6fw6q 4172 19 assessed assess VBN cord-006870-f5w6fw6q 4172 20 by by IN cord-006870-f5w6fw6q 4172 21 Modified Modified NNP cord-006870-f5w6fw6q 4172 22 Rankin Rankin NNP cord-006870-f5w6fw6q 4172 23 scale scale NN cord-006870-f5w6fw6q 4172 24 . . . cord-006870-f5w6fw6q 4173 1 One one CD cord-006870-f5w6fw6q 4173 2 patient patient NN cord-006870-f5w6fw6q 4173 3 was be VBD cord-006870-f5w6fw6q 4173 4 discharged discharge VBN cord-006870-f5w6fw6q 4173 5 to to IN cord-006870-f5w6fw6q 4173 6 inpatient inpatient JJ cord-006870-f5w6fw6q 4173 7 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 4173 8 for for IN cord-006870-f5w6fw6q 4173 9 cognitive cognitive JJ cord-006870-f5w6fw6q 4173 10 deficits deficit NNS cord-006870-f5w6fw6q 4173 11 from from IN cord-006870-f5w6fw6q 4173 12 IPR IPR NNP cord-006870-f5w6fw6q 4173 13 of of IN cord-006870-f5w6fw6q 4173 14 a a DT cord-006870-f5w6fw6q 4173 15 basilar basilar JJ cord-006870-f5w6fw6q 4173 16 apex apex NN cord-006870-f5w6fw6q 4173 17 aneurysm aneurysm NN cord-006870-f5w6fw6q 4173 18 . . . cord-006870-f5w6fw6q 4174 1 They -PRON- PRP cord-006870-f5w6fw6q 4174 2 were be VBD cord-006870-f5w6fw6q 4174 3 subsequently subsequently RB cord-006870-f5w6fw6q 4174 4 discharged discharge VBN cord-006870-f5w6fw6q 4174 5 home home RB cord-006870-f5w6fw6q 4174 6 with with IN cord-006870-f5w6fw6q 4174 7 supervision supervision NN cord-006870-f5w6fw6q 4174 8 . . . cord-006870-f5w6fw6q 4175 1 There there EX cord-006870-f5w6fw6q 4175 2 was be VBD cord-006870-f5w6fw6q 4175 3 a a DT cord-006870-f5w6fw6q 4175 4 single single JJ cord-006870-f5w6fw6q 4175 5 mortality mortality NN cord-006870-f5w6fw6q 4175 6 in in IN cord-006870-f5w6fw6q 4175 7 a a DT cord-006870-f5w6fw6q 4175 8 patient patient NN cord-006870-f5w6fw6q 4175 9 receiving receive VBG cord-006870-f5w6fw6q 4175 10 retreatment retreatment NN cord-006870-f5w6fw6q 4175 11 of of IN cord-006870-f5w6fw6q 4175 12 a a DT cord-006870-f5w6fw6q 4175 13 proximal proximal JJ cord-006870-f5w6fw6q 4175 14 ICA ICA NNP cord-006870-f5w6fw6q 4175 15 aneurysm aneurysm NN cord-006870-f5w6fw6q 4175 16 with with IN cord-006870-f5w6fw6q 4175 17 prior prior JJ cord-006870-f5w6fw6q 4175 18 stenting stenting NN cord-006870-f5w6fw6q 4175 19 and and CC cord-006870-f5w6fw6q 4175 20 coil coil NN cord-006870-f5w6fw6q 4175 21 embolization embolization NN cord-006870-f5w6fw6q 4175 22 who who WP cord-006870-f5w6fw6q 4175 23 developed develop VBD cord-006870-f5w6fw6q 4175 24 massive massive JJ cord-006870-f5w6fw6q 4175 25 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4175 26 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4175 27 with with IN cord-006870-f5w6fw6q 4175 28 diffuse diffuse JJ cord-006870-f5w6fw6q 4175 29 intraventricular intraventricular JJ cord-006870-f5w6fw6q 4175 30 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4175 31 with with IN cord-006870-f5w6fw6q 4175 32 external external JJ cord-006870-f5w6fw6q 4175 33 ventricular ventricular JJ cord-006870-f5w6fw6q 4175 34 drain drain NN cord-006870-f5w6fw6q 4175 35 placement placement NN cord-006870-f5w6fw6q 4175 36 . . . cord-006870-f5w6fw6q 4176 1 The the DT cord-006870-f5w6fw6q 4176 2 incidence incidence NN cord-006870-f5w6fw6q 4176 3 of of IN cord-006870-f5w6fw6q 4176 4 IPR IPR NNP cord-006870-f5w6fw6q 4176 5 is be VBZ cord-006870-f5w6fw6q 4176 6 very very RB cord-006870-f5w6fw6q 4176 7 low low JJ cord-006870-f5w6fw6q 4176 8 and and CC cord-006870-f5w6fw6q 4176 9 potentially potentially RB cord-006870-f5w6fw6q 4176 10 serious serious JJ cord-006870-f5w6fw6q 4176 11 complications complication NNS cord-006870-f5w6fw6q 4176 12 occur occur VBP cord-006870-f5w6fw6q 4176 13 rarely rarely RB cord-006870-f5w6fw6q 4176 14 in in IN cord-006870-f5w6fw6q 4176 15 these these DT cord-006870-f5w6fw6q 4176 16 patients patient NNS cord-006870-f5w6fw6q 4176 17 . . . cord-006870-f5w6fw6q 4177 1 The the DT cord-006870-f5w6fw6q 4177 2 location location NN cord-006870-f5w6fw6q 4177 3 and and CC cord-006870-f5w6fw6q 4177 4 factors factor NNS cord-006870-f5w6fw6q 4177 5 associated associate VBN cord-006870-f5w6fw6q 4177 6 with with IN cord-006870-f5w6fw6q 4177 7 IPR IPR NNP cord-006870-f5w6fw6q 4177 8 are be VBP cord-006870-f5w6fw6q 4177 9 highly highly RB cord-006870-f5w6fw6q 4177 10 variable variable JJ cord-006870-f5w6fw6q 4177 11 and and CC cord-006870-f5w6fw6q 4177 12 without without IN cord-006870-f5w6fw6q 4177 13 clear clear JJ cord-006870-f5w6fw6q 4177 14 associations association NNS cord-006870-f5w6fw6q 4177 15 . . . cord-006870-f5w6fw6q 4178 1 Outcomes outcome NNS cord-006870-f5w6fw6q 4178 2 of of IN cord-006870-f5w6fw6q 4178 3 such such JJ cord-006870-f5w6fw6q 4178 4 complications complication NNS cord-006870-f5w6fw6q 4178 5 are be VBP cord-006870-f5w6fw6q 4178 6 overall overall RB cord-006870-f5w6fw6q 4178 7 favorable favorable JJ cord-006870-f5w6fw6q 4178 8 . . . cord-006870-f5w6fw6q 4179 1 A a DT cord-006870-f5w6fw6q 4179 2 short short JJ cord-006870-f5w6fw6q 4179 3 observation observation NN cord-006870-f5w6fw6q 4179 4 period period NN cord-006870-f5w6fw6q 4179 5 in in IN cord-006870-f5w6fw6q 4179 6 the the DT cord-006870-f5w6fw6q 4179 7 hospital hospital NN cord-006870-f5w6fw6q 4179 8 is be VBZ cord-006870-f5w6fw6q 4179 9 likely likely RB cord-006870-f5w6fw6q 4179 10 warranted warrant VBN cord-006870-f5w6fw6q 4179 11 with with IN cord-006870-f5w6fw6q 4179 12 a a DT cord-006870-f5w6fw6q 4179 13 benign benign JJ cord-006870-f5w6fw6q 4179 14 clinical clinical JJ cord-006870-f5w6fw6q 4179 15 course course NN cord-006870-f5w6fw6q 4179 16 the the DT cord-006870-f5w6fw6q 4179 17 most most RBS cord-006870-f5w6fw6q 4179 18 likely likely JJ cord-006870-f5w6fw6q 4179 19 outcome outcome NN cord-006870-f5w6fw6q 4179 20 . . . cord-006870-f5w6fw6q 4180 1 The the DT cord-006870-f5w6fw6q 4180 2 standard standard JJ cord-006870-f5w6fw6q 4180 3 treatment treatment NN cord-006870-f5w6fw6q 4180 4 of of IN cord-006870-f5w6fw6q 4180 5 Cerebral Cerebral NNP cord-006870-f5w6fw6q 4180 6 Venous venous JJ cord-006870-f5w6fw6q 4180 7 - - HYPH cord-006870-f5w6fw6q 4180 8 Sinus Sinus NNP cord-006870-f5w6fw6q 4180 9 Thrombosis thrombosis NN cord-006870-f5w6fw6q 4180 10 ( ( -LRB- cord-006870-f5w6fw6q 4180 11 CVST CVST NNP cord-006870-f5w6fw6q 4180 12 ) ) -RRB- cord-006870-f5w6fw6q 4180 13 is be VBZ cord-006870-f5w6fw6q 4180 14 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 4180 15 . . . cord-006870-f5w6fw6q 4181 1 However however RB cord-006870-f5w6fw6q 4181 2 some some DT cord-006870-f5w6fw6q 4181 3 patients patient NNS cord-006870-f5w6fw6q 4181 4 clinically clinically RB cord-006870-f5w6fw6q 4181 5 deteriorate deteriorate VBP cord-006870-f5w6fw6q 4181 6 secondary secondary JJ cord-006870-f5w6fw6q 4181 7 to to IN cord-006870-f5w6fw6q 4181 8 mass mass JJ cord-006870-f5w6fw6q 4181 9 - - HYPH cord-006870-f5w6fw6q 4181 10 effect effect NN cord-006870-f5w6fw6q 4181 11 from from IN cord-006870-f5w6fw6q 4181 12 infarct infarct NN cord-006870-f5w6fw6q 4181 13 or or CC cord-006870-f5w6fw6q 4181 14 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 4181 15 - - HYPH cord-006870-f5w6fw6q 4181 16 Hemorrhage Hemorrhage NNP cord-006870-f5w6fw6q 4181 17 ( ( -LRB- cord-006870-f5w6fw6q 4181 18 ICH ICH NNP cord-006870-f5w6fw6q 4181 19 ) ) -RRB- cord-006870-f5w6fw6q 4181 20 . . . cord-006870-f5w6fw6q 4182 1 The the DT cord-006870-f5w6fw6q 4182 2 role role NN cord-006870-f5w6fw6q 4182 3 of of IN cord-006870-f5w6fw6q 4182 4 decompressive decompressive JJ cord-006870-f5w6fw6q 4182 5 - - HYPH cord-006870-f5w6fw6q 4182 6 craniectomy craniectomy NN cord-006870-f5w6fw6q 4182 7 ( ( -LRB- cord-006870-f5w6fw6q 4182 8 DC DC NNP cord-006870-f5w6fw6q 4182 9 ) ) -RRB- cord-006870-f5w6fw6q 4182 10 in in IN cord-006870-f5w6fw6q 4182 11 this this DT cord-006870-f5w6fw6q 4182 12 patient patient JJ cord-006870-f5w6fw6q 4182 13 population population NN cord-006870-f5w6fw6q 4182 14 is be VBZ cord-006870-f5w6fw6q 4182 15 unknown unknown JJ cord-006870-f5w6fw6q 4182 16 . . . cord-006870-f5w6fw6q 4183 1 We -PRON- PRP cord-006870-f5w6fw6q 4183 2 elucidate elucidate VBP cord-006870-f5w6fw6q 4183 3 the the DT cord-006870-f5w6fw6q 4183 4 baseline baseline JJ cord-006870-f5w6fw6q 4183 5 characteristics characteristic NNS cord-006870-f5w6fw6q 4183 6 of of IN cord-006870-f5w6fw6q 4183 7 patients patient NNS cord-006870-f5w6fw6q 4183 8 treated treat VBN cord-006870-f5w6fw6q 4183 9 with with IN cord-006870-f5w6fw6q 4183 10 DC DC NNP cord-006870-f5w6fw6q 4183 11 , , , cord-006870-f5w6fw6q 4183 12 and and CC cord-006870-f5w6fw6q 4183 13 report report VB cord-006870-f5w6fw6q 4183 14 their -PRON- PRP$ cord-006870-f5w6fw6q 4183 15 outcomes outcome NNS cord-006870-f5w6fw6q 4183 16 . . . cord-006870-f5w6fw6q 4184 1 A a DT cord-006870-f5w6fw6q 4184 2 retrospective retrospective JJ cord-006870-f5w6fw6q 4184 3 chart chart NN cord-006870-f5w6fw6q 4184 4 review review NN cord-006870-f5w6fw6q 4184 5 of of IN cord-006870-f5w6fw6q 4184 6 our -PRON- PRP$ cord-006870-f5w6fw6q 4184 7 institutional institutional JJ cord-006870-f5w6fw6q 4184 8 database database NN cord-006870-f5w6fw6q 4184 9 identified identify VBD cord-006870-f5w6fw6q 4184 10 patients patient NNS cord-006870-f5w6fw6q 4184 11 with with IN cord-006870-f5w6fw6q 4184 12 CVST CVST NNP cord-006870-f5w6fw6q 4184 13 who who WP cord-006870-f5w6fw6q 4184 14 were be VBD cord-006870-f5w6fw6q 4184 15 treated treat VBN cord-006870-f5w6fw6q 4184 16 with with IN cord-006870-f5w6fw6q 4184 17 DC DC NNP cord-006870-f5w6fw6q 4184 18 . . . cord-006870-f5w6fw6q 4185 1 Demographic demographic JJ cord-006870-f5w6fw6q 4185 2 and and CC cord-006870-f5w6fw6q 4185 3 clinical clinical JJ cord-006870-f5w6fw6q 4185 4 data datum NNS cord-006870-f5w6fw6q 4185 5 were be VBD cord-006870-f5w6fw6q 4185 6 collected collect VBN cord-006870-f5w6fw6q 4185 7 . . . cord-006870-f5w6fw6q 4186 1 Imaging imaging NN cord-006870-f5w6fw6q 4186 2 variables variable NNS cord-006870-f5w6fw6q 4186 3 collected collect VBN cord-006870-f5w6fw6q 4186 4 from from IN cord-006870-f5w6fw6q 4186 5 CT CT NNP cord-006870-f5w6fw6q 4186 6 - - HYPH cord-006870-f5w6fw6q 4186 7 Head Head NNP cord-006870-f5w6fw6q 4186 8 or or CC cord-006870-f5w6fw6q 4186 9 MRI MRI NNP cord-006870-f5w6fw6q 4186 10 - - HYPH cord-006870-f5w6fw6q 4186 11 Brain Brain NNP cord-006870-f5w6fw6q 4186 12 immediately immediately RB cord-006870-f5w6fw6q 4186 13 before before IN cord-006870-f5w6fw6q 4186 14 DC DC NNP cord-006870-f5w6fw6q 4186 15 were be VBD cord-006870-f5w6fw6q 4186 16 intracerebral intracerebral JJ cord-006870-f5w6fw6q 4186 17 - - HYPH cord-006870-f5w6fw6q 4186 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4186 19 volume volume NN cord-006870-f5w6fw6q 4186 20 ( ( -LRB- cord-006870-f5w6fw6q 4186 21 ICH ICH NNP cord-006870-f5w6fw6q 4186 22 - - HYPH cord-006870-f5w6fw6q 4186 23 V V NNP cord-006870-f5w6fw6q 4186 24 ) ) -RRB- cord-006870-f5w6fw6q 4186 25 , , , cord-006870-f5w6fw6q 4186 26 combined combine VBN cord-006870-f5w6fw6q 4186 27 volume volume NN cord-006870-f5w6fw6q 4186 28 of of IN cord-006870-f5w6fw6q 4186 29 mass mass JJ cord-006870-f5w6fw6q 4186 30 - - HYPH cord-006870-f5w6fw6q 4186 31 effect effect NN cord-006870-f5w6fw6q 4186 32 from from IN cord-006870-f5w6fw6q 4186 33 infarct infarct NNP cord-006870-f5w6fw6q 4186 34 / / SYM cord-006870-f5w6fw6q 4186 35 ICH ICH NNP cord-006870-f5w6fw6q 4186 36 and and CC cord-006870-f5w6fw6q 4186 37 peri peri JJ cord-006870-f5w6fw6q 4186 38 - - HYPH cord-006870-f5w6fw6q 4186 39 lesional lesional JJ cord-006870-f5w6fw6q 4186 40 edema edema NN cord-006870-f5w6fw6q 4186 41 ( ( -LRB- cord-006870-f5w6fw6q 4186 42 ME ME NNP cord-006870-f5w6fw6q 4186 43 - - HYPH cord-006870-f5w6fw6q 4186 44 V V NNP cord-006870-f5w6fw6q 4186 45 ) ) -RRB- cord-006870-f5w6fw6q 4186 46 , , , cord-006870-f5w6fw6q 4186 47 midline midline JJ cord-006870-f5w6fw6q 4186 48 - - HYPH cord-006870-f5w6fw6q 4186 49 shift shift NN cord-006870-f5w6fw6q 4186 50 at at IN cord-006870-f5w6fw6q 4186 51 level level NN cord-006870-f5w6fw6q 4186 52 of of IN cord-006870-f5w6fw6q 4186 53 pinealgland pinealgland NN cord-006870-f5w6fw6q 4187 1 ( ( -LRB- cord-006870-f5w6fw6q 4187 2 MDS MDS NNP cord-006870-f5w6fw6q 4187 3 - - HYPH cord-006870-f5w6fw6q 4187 4 P p NN cord-006870-f5w6fw6q 4187 5 ) ) -RRB- cord-006870-f5w6fw6q 4188 1 , , , cord-006870-f5w6fw6q 4188 2 midline midline JJ cord-006870-f5w6fw6q 4188 3 - - HYPH cord-006870-f5w6fw6q 4188 4 shift shift NN cord-006870-f5w6fw6q 4188 5 at at IN cord-006870-f5w6fw6q 4188 6 cranial cranial NN cord-006870-f5w6fw6q 4188 7 - - HYPH cord-006870-f5w6fw6q 4188 8 most most JJS cord-006870-f5w6fw6q 4188 9 portion portion NN cord-006870-f5w6fw6q 4188 10 of of IN cord-006870-f5w6fw6q 4188 11 corpus corpus NNP cord-006870-f5w6fw6q 4188 12 - - HYPH cord-006870-f5w6fw6q 4188 13 callosum callosum NNP cord-006870-f5w6fw6q 4188 14 ( ( -LRB- cord-006870-f5w6fw6q 4188 15 MDS MDS NNP cord-006870-f5w6fw6q 4188 16 - - HYPH cord-006870-f5w6fw6q 4188 17 CC CC NNP cord-006870-f5w6fw6q 4188 18 ) ) -RRB- cord-006870-f5w6fw6q 4188 19 , , , cord-006870-f5w6fw6q 4188 20 and and CC cord-006870-f5w6fw6q 4188 21 herniation herniation NN cord-006870-f5w6fw6q 4188 22 - - HYPH cord-006870-f5w6fw6q 4188 23 type type NN cord-006870-f5w6fw6q 4188 24 . . . cord-006870-f5w6fw6q 4189 1 Favorable favorable JJ cord-006870-f5w6fw6q 4189 2 outcome outcome NN cord-006870-f5w6fw6q 4189 3 was be VBD cord-006870-f5w6fw6q 4189 4 defined define VBN cord-006870-f5w6fw6q 4189 5 as as IN cord-006870-f5w6fw6q 4189 6 Glasgow Glasgow NNP cord-006870-f5w6fw6q 4189 7 - - HYPH cord-006870-f5w6fw6q 4189 8 Outcomes Outcomes NNP cord-006870-f5w6fw6q 4189 9 Scale scale NN cord-006870-f5w6fw6q 4189 10 of of IN cord-006870-f5w6fw6q 4189 11 4 4 CD cord-006870-f5w6fw6q 4189 12 - - SYM cord-006870-f5w6fw6q 4189 13 5 5 CD cord-006870-f5w6fw6q 4189 14 upon upon IN cord-006870-f5w6fw6q 4189 15 last last RB cord-006870-f5w6fw6q 4189 16 - - HYPH cord-006870-f5w6fw6q 4189 17 known know VBN cord-006870-f5w6fw6q 4189 18 follow follow NN cord-006870-f5w6fw6q 4189 19 - - HYPH cord-006870-f5w6fw6q 4189 20 up up NN cord-006870-f5w6fw6q 4189 21 . . . cord-006870-f5w6fw6q 4190 1 A a DT cord-006870-f5w6fw6q 4190 2 total total NN cord-006870-f5w6fw6q 4190 3 of of IN cord-006870-f5w6fw6q 4190 4 15 15 CD cord-006870-f5w6fw6q 4190 5 patients patient NNS cord-006870-f5w6fw6q 4190 6 ( ( -LRB- cord-006870-f5w6fw6q 4190 7 females=10 females=10 NNP cord-006870-f5w6fw6q 4190 8 ) ) -RRB- cord-006870-f5w6fw6q 4190 9 treated treat VBN cord-006870-f5w6fw6q 4190 10 with with IN cord-006870-f5w6fw6q 4190 11 DC DC NNP cord-006870-f5w6fw6q 4190 12 were be VBD cord-006870-f5w6fw6q 4190 13 identified identify VBN cord-006870-f5w6fw6q 4190 14 with with IN cord-006870-f5w6fw6q 4190 15 mean mean NN cord-006870-f5w6fw6q 4190 16 - - HYPH cord-006870-f5w6fw6q 4190 17 age age NN cord-006870-f5w6fw6q 4190 18 46.7 46.7 CD cord-006870-f5w6fw6q 4190 19 ( ( -LRB- cord-006870-f5w6fw6q 4190 20 + + CD cord-006870-f5w6fw6q 4190 21 /-17.4 /-17.4 NN cord-006870-f5w6fw6q 4190 22 ) ) -RRB- cord-006870-f5w6fw6q 4191 1 , , , cord-006870-f5w6fw6q 4191 2 mean mean VB cord-006870-f5w6fw6q 4191 3 Glasgow Glasgow NNP cord-006870-f5w6fw6q 4191 4 - - HYPH cord-006870-f5w6fw6q 4191 5 Coma Coma NNP cord-006870-f5w6fw6q 4191 6 Scale Scale NNP cord-006870-f5w6fw6q 4191 7 ( ( -LRB- cord-006870-f5w6fw6q 4191 8 GCS GCS NNP cord-006870-f5w6fw6q 4191 9 ) ) -RRB- cord-006870-f5w6fw6q 4191 10 before before IN cord-006870-f5w6fw6q 4191 11 surgery surgery NN cord-006870-f5w6fw6q 4191 12 8 8 CD cord-006870-f5w6fw6q 4191 13 ( ( -LRB- cord-006870-f5w6fw6q 4191 14 + + CC cord-006870-f5w6fw6q 4191 15 /-3.9 /-3.9 NNP cord-006870-f5w6fw6q 4191 16 ) ) -RRB- cord-006870-f5w6fw6q 4191 17 , , , cord-006870-f5w6fw6q 4191 18 mean mean JJ cord-006870-f5w6fw6q 4191 19 - - HYPH cord-006870-f5w6fw6q 4191 20 ICH ICH NNP cord-006870-f5w6fw6q 4191 21 - - HYPH cord-006870-f5w6fw6q 4191 22 V v NN cord-006870-f5w6fw6q 4191 23 42.2 42.2 CD cord-006870-f5w6fw6q 4191 24 ml ml NNS cord-006870-f5w6fw6q 4191 25 ( ( -LRB- cord-006870-f5w6fw6q 4191 26 + + `` cord-006870-f5w6fw6q 4191 27 /-44.0 /-44.0 NN cord-006870-f5w6fw6q 4191 28 ) ) -RRB- cord-006870-f5w6fw6q 4191 29 , , , cord-006870-f5w6fw6q 4191 30 mean mean VB cord-006870-f5w6fw6q 4191 31 - - HYPH cord-006870-f5w6fw6q 4191 32 ME ME NNP cord-006870-f5w6fw6q 4191 33 - - HYPH cord-006870-f5w6fw6q 4191 34 V v NN cord-006870-f5w6fw6q 4192 1 100.7 100.7 CD cord-006870-f5w6fw6q 4192 2 ml ml NN cord-006870-f5w6fw6q 4192 3 ( ( -LRB- cord-006870-f5w6fw6q 4192 4 + + `` cord-006870-f5w6fw6q 4192 5 /-51.6 /-51.6 . cord-006870-f5w6fw6q 4192 6 ) ) -RRB- cord-006870-f5w6fw6q 4192 7 , , , cord-006870-f5w6fw6q 4192 8 mean mean NN cord-006870-f5w6fw6q 4192 9 - - HYPH cord-006870-f5w6fw6q 4192 10 MDS mds NN cord-006870-f5w6fw6q 4192 11 - - HYPH cord-006870-f5w6fw6q 4192 12 P p NN cord-006870-f5w6fw6q 4192 13 6.1 6.1 CD cord-006870-f5w6fw6q 4192 14 mm mm NN cord-006870-f5w6fw6q 4192 15 ( ( -LRB- cord-006870-f5w6fw6q 4192 16 + + CC cord-006870-f5w6fw6q 4192 17 /-3.9 /-3.9 NNP cord-006870-f5w6fw6q 4192 18 ) ) -RRB- cord-006870-f5w6fw6q 4192 19 , , , cord-006870-f5w6fw6q 4192 20 and and CC cord-006870-f5w6fw6q 4192 21 mean mean JJ cord-006870-f5w6fw6q 4192 22 - - HYPH cord-006870-f5w6fw6q 4192 23 MDS mds NN cord-006870-f5w6fw6q 4192 24 - - HYPH cord-006870-f5w6fw6q 4192 25 CC CC NNP cord-006870-f5w6fw6q 4192 26 7.4 7.4 CD cord-006870-f5w6fw6q 4192 27 mm mm NN cord-006870-f5w6fw6q 4192 28 ( ( -LRB- cord-006870-f5w6fw6q 4192 29 + + CC cord-006870-f5w6fw6q 4192 30 /-6.5 /-6.5 . cord-006870-f5w6fw6q 4192 31 ) ) -RRB- cord-006870-f5w6fw6q 4192 32 . . . cord-006870-f5w6fw6q 4193 1 Transverse transverse JJ cord-006870-f5w6fw6q 4193 2 - - HYPH cord-006870-f5w6fw6q 4193 3 sinus sinus NN cord-006870-f5w6fw6q 4193 4 was be VBD cord-006870-f5w6fw6q 4193 5 most most RBS cord-006870-f5w6fw6q 4193 6 commonly commonly RB cord-006870-f5w6fw6q 4193 7 involved involve VBN cord-006870-f5w6fw6q 4193 8 ( ( -LRB- cord-006870-f5w6fw6q 4193 9 n=10 n=10 NNP cord-006870-f5w6fw6q 4193 10 ) ) -RRB- cord-006870-f5w6fw6q 4193 11 . . . cord-006870-f5w6fw6q 4194 1 14/15 14/15 CD cord-006870-f5w6fw6q 4194 2 patients patient NNS cord-006870-f5w6fw6q 4194 3 had have VBD cord-006870-f5w6fw6q 4194 4 any any DT cord-006870-f5w6fw6q 4194 5 herniation herniation NN cord-006870-f5w6fw6q 4194 6 , , , cord-006870-f5w6fw6q 4194 7 most most RBS cord-006870-f5w6fw6q 4194 8 commonly commonly RB cord-006870-f5w6fw6q 4194 9 cingulate cingulate NNP cord-006870-f5w6fw6q 4194 10 ( ( -LRB- cord-006870-f5w6fw6q 4194 11 n=10 n=10 NNP cord-006870-f5w6fw6q 4194 12 ) ) -RRB- cord-006870-f5w6fw6q 4194 13 . . . cord-006870-f5w6fw6q 4195 1 Meanchange Meanchange NNP cord-006870-f5w6fw6q 4195 2 in in IN cord-006870-f5w6fw6q 4195 3 GCS GCS NNP cord-006870-f5w6fw6q 4195 4 from from IN cord-006870-f5w6fw6q 4195 5 admission admission NN cord-006870-f5w6fw6q 4195 6 to to IN cord-006870-f5w6fw6q 4195 7 before before IN cord-006870-f5w6fw6q 4195 8 - - HYPH cord-006870-f5w6fw6q 4195 9 surgery surgery NN cord-006870-f5w6fw6q 4195 10 was be VBD cord-006870-f5w6fw6q 4195 11 -4.8 -4.8 : cord-006870-f5w6fw6q 4195 12 ( ( -LRB- cord-006870-f5w6fw6q 4195 13 + + CC cord-006870-f5w6fw6q 4195 14 /-4.2 /-4.2 . cord-006870-f5w6fw6q 4195 15 ) ) -RRB- cord-006870-f5w6fw6q 4195 16 . . . cord-006870-f5w6fw6q 4196 1 Ten ten CD cord-006870-f5w6fw6q 4196 2 patients patient NNS cord-006870-f5w6fw6q 4196 3 were be VBD cord-006870-f5w6fw6q 4196 4 anticoagulated anticoagulate VBN cord-006870-f5w6fw6q 4196 5 before before IN cord-006870-f5w6fw6q 4196 6 surgery surgery NN cord-006870-f5w6fw6q 4196 7 . . . cord-006870-f5w6fw6q 4197 1 On on IN cord-006870-f5w6fw6q 4197 2 last last RB cord-006870-f5w6fw6q 4197 3 - - HYPH cord-006870-f5w6fw6q 4197 4 known know VBN cord-006870-f5w6fw6q 4197 5 follow follow NN cord-006870-f5w6fw6q 4197 6 - - HYPH cord-006870-f5w6fw6q 4197 7 up up NN cord-006870-f5w6fw6q 4197 8 , , , cord-006870-f5w6fw6q 4197 9 9/15 9/15 CD cord-006870-f5w6fw6q 4197 10 patients patient NNS cord-006870-f5w6fw6q 4197 11 had have VBD cord-006870-f5w6fw6q 4197 12 a a DT cord-006870-f5w6fw6q 4197 13 favorable favorable JJ cord-006870-f5w6fw6q 4197 14 outcome outcome NN cord-006870-f5w6fw6q 4197 15 . . . cord-006870-f5w6fw6q 4198 1 Four four CD cord-006870-f5w6fw6q 4198 2 had have VBD cord-006870-f5w6fw6q 4198 3 died die VBN cord-006870-f5w6fw6q 4198 4 . . . cord-006870-f5w6fw6q 4199 1 On on IN cord-006870-f5w6fw6q 4199 2 chisquare chisquare NN cord-006870-f5w6fw6q 4199 3 analysis analysis NN cord-006870-f5w6fw6q 4199 4 , , , cord-006870-f5w6fw6q 4199 5 Superior Superior NNP cord-006870-f5w6fw6q 4199 6 - - HYPH cord-006870-f5w6fw6q 4199 7 Sagittal Sagittal NNP cord-006870-f5w6fw6q 4199 8 Sinus sinus NN cord-006870-f5w6fw6q 4199 9 thrombosis thrombosis NN cord-006870-f5w6fw6q 4199 10 was be VBD cord-006870-f5w6fw6q 4199 11 associated associate VBN cord-006870-f5w6fw6q 4199 12 with with IN cord-006870-f5w6fw6q 4199 13 unfavorable unfavorable JJ cord-006870-f5w6fw6q 4199 14 outcomes outcome NNS cord-006870-f5w6fw6q 4199 15 ( ( -LRB- cord-006870-f5w6fw6q 4199 16 p=0.025 p=0.025 NNP cord-006870-f5w6fw6q 4199 17 ) ) -RRB- cord-006870-f5w6fw6q 4199 18 , , , cord-006870-f5w6fw6q 4199 19 and and CC cord-006870-f5w6fw6q 4199 20 mortality mortality NN cord-006870-f5w6fw6q 4199 21 ( ( -LRB- cord-006870-f5w6fw6q 4199 22 p=0.039 p=0.039 NNP cord-006870-f5w6fw6q 4199 23 ) ) -RRB- cord-006870-f5w6fw6q 4199 24 . . . cord-006870-f5w6fw6q 4200 1 On on IN cord-006870-f5w6fw6q 4200 2 univariate univariate JJ cord-006870-f5w6fw6q 4200 3 binary binary JJ cord-006870-f5w6fw6q 4200 4 - - HYPH cord-006870-f5w6fw6q 4200 5 logistic logistic JJ cord-006870-f5w6fw6q 4200 6 regression regression NN cord-006870-f5w6fw6q 4200 7 , , , cord-006870-f5w6fw6q 4200 8 there there EX cord-006870-f5w6fw6q 4200 9 was be VBD cord-006870-f5w6fw6q 4200 10 a a DT cord-006870-f5w6fw6q 4200 11 non non JJ cord-006870-f5w6fw6q 4200 12 - - JJ cord-006870-f5w6fw6q 4200 13 significant significant JJ cord-006870-f5w6fw6q 4200 14 trend trend NN cord-006870-f5w6fw6q 4200 15 towards towards IN cord-006870-f5w6fw6q 4200 16 unfavorable unfavorable JJ cord-006870-f5w6fw6q 4200 17 outcomes outcome NNS cord-006870-f5w6fw6q 4200 18 ( ( -LRB- cord-006870-f5w6fw6q 4200 19 p=0.082 p=0.082 NN cord-006870-f5w6fw6q 4200 20 ) ) -RRB- cord-006870-f5w6fw6q 4200 21 and and CC cord-006870-f5w6fw6q 4200 22 mortality mortality NN cord-006870-f5w6fw6q 4200 23 ( ( -LRB- cord-006870-f5w6fw6q 4200 24 p=0.079 p=0.079 ADD cord-006870-f5w6fw6q 4200 25 ) ) -RRB- cord-006870-f5w6fw6q 4200 26 with with IN cord-006870-f5w6fw6q 4200 27 every every DT cord-006870-f5w6fw6q 4200 28 - - HYPH cord-006870-f5w6fw6q 4200 29 point point NN cord-006870-f5w6fw6q 4200 30 decrease decrease NN cord-006870-f5w6fw6q 4200 31 in in IN cord-006870-f5w6fw6q 4200 32 mean mean NN cord-006870-f5w6fw6q 4200 33 - - HYPH cord-006870-f5w6fw6q 4200 34 GCS gcs NN cord-006870-f5w6fw6q 4200 35 before before IN cord-006870-f5w6fw6q 4200 36 surgery surgery NN cord-006870-f5w6fw6q 4200 37 . . . cord-006870-f5w6fw6q 4201 1 The the DT cord-006870-f5w6fw6q 4201 2 predictive predictive JJ cord-006870-f5w6fw6q 4201 3 - - HYPH cord-006870-f5w6fw6q 4201 4 value value NN cord-006870-f5w6fw6q 4201 5 of of IN cord-006870-f5w6fw6q 4201 6 other other JJ cord-006870-f5w6fw6q 4201 7 factors factor NNS cord-006870-f5w6fw6q 4201 8 towards towards IN cord-006870-f5w6fw6q 4201 9 outcomes outcome NNS cord-006870-f5w6fw6q 4201 10 is be VBZ cord-006870-f5w6fw6q 4201 11 unknown unknown JJ cord-006870-f5w6fw6q 4201 12 given give VBN cord-006870-f5w6fw6q 4201 13 limited limited JJ cord-006870-f5w6fw6q 4201 14 sample sample NN cord-006870-f5w6fw6q 4201 15 - - HYPH cord-006870-f5w6fw6q 4201 16 size size NN cord-006870-f5w6fw6q 4201 17 . . . cord-006870-f5w6fw6q 4202 1 Decompressive Decompressive NNP cord-006870-f5w6fw6q 4202 2 - - HYPH cord-006870-f5w6fw6q 4202 3 craniectomy craniectomy NN cord-006870-f5w6fw6q 4202 4 might may MD cord-006870-f5w6fw6q 4202 5 improve improve VB cord-006870-f5w6fw6q 4202 6 outcomes outcome NNS cord-006870-f5w6fw6q 4202 7 even even RB cord-006870-f5w6fw6q 4202 8 in in IN cord-006870-f5w6fw6q 4202 9 patients patient NNS cord-006870-f5w6fw6q 4202 10 with with IN cord-006870-f5w6fw6q 4202 11 CVST CVST NNP cord-006870-f5w6fw6q 4202 12 who who WP cord-006870-f5w6fw6q 4202 13 have have VBP cord-006870-f5w6fw6q 4202 14 developed develop VBN cord-006870-f5w6fw6q 4202 15 coma coma NN cord-006870-f5w6fw6q 4202 16 , , , cord-006870-f5w6fw6q 4202 17 cerebral cerebral JJ cord-006870-f5w6fw6q 4202 18 herniation herniation NN cord-006870-f5w6fw6q 4202 19 , , , cord-006870-f5w6fw6q 4202 20 have have VBP cord-006870-f5w6fw6q 4202 21 failed fail VBN cord-006870-f5w6fw6q 4202 22 treatment treatment NN cord-006870-f5w6fw6q 4202 23 with with IN cord-006870-f5w6fw6q 4202 24 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 4202 25 , , , cord-006870-f5w6fw6q 4202 26 and and CC cord-006870-f5w6fw6q 4202 27 have have VBP cord-006870-f5w6fw6q 4202 28 large large JJ cord-006870-f5w6fw6q 4202 29 - - HYPH cord-006870-f5w6fw6q 4202 30 volume volume NN cord-006870-f5w6fw6q 4202 31 masslesions masslesion NNS cord-006870-f5w6fw6q 4202 32 causing cause VBG cord-006870-f5w6fw6q 4202 33 midline midline NN cord-006870-f5w6fw6q 4202 34 - - HYPH cord-006870-f5w6fw6q 4202 35 shifts shift NNS cord-006870-f5w6fw6q 4202 36 of of IN cord-006870-f5w6fw6q 4202 37 > > NN cord-006870-f5w6fw6q 4202 38 5 5 CD cord-006870-f5w6fw6q 4202 39 mm mm NN cord-006870-f5w6fw6q 4202 40 . . . cord-006870-f5w6fw6q 4203 1 A a DT cord-006870-f5w6fw6q 4203 2 prospective prospective JJ cord-006870-f5w6fw6q 4203 3 multi multi JJ cord-006870-f5w6fw6q 4203 4 - - JJ cord-006870-f5w6fw6q 4203 5 institutional institutional JJ cord-006870-f5w6fw6q 4203 6 observational observational JJ cord-006870-f5w6fw6q 4203 7 - - HYPH cord-006870-f5w6fw6q 4203 8 cohort cohort NN cord-006870-f5w6fw6q 4203 9 would would MD cord-006870-f5w6fw6q 4203 10 POSTER poster VB cord-006870-f5w6fw6q 4203 11 PRESENTATIONS presentation NNS cord-006870-f5w6fw6q 4204 1 better well RBR cord-006870-f5w6fw6q 4204 2 delineate delineate VB cord-006870-f5w6fw6q 4204 3 outcomes outcome NNS cord-006870-f5w6fw6q 4204 4 in in IN cord-006870-f5w6fw6q 4204 5 comparison comparison NN cord-006870-f5w6fw6q 4204 6 to to IN cord-006870-f5w6fw6q 4204 7 matched match VBN cord-006870-f5w6fw6q 4204 8 - - HYPH cord-006870-f5w6fw6q 4204 9 patients patient NNS cord-006870-f5w6fw6q 4204 10 who who WP cord-006870-f5w6fw6q 4204 11 are be VBP cord-006870-f5w6fw6q 4204 12 not not RB cord-006870-f5w6fw6q 4204 13 treated treat VBN cord-006870-f5w6fw6q 4204 14 with with IN cord-006870-f5w6fw6q 4204 15 decompressivecraniectomy decompressivecraniectomy NN cord-006870-f5w6fw6q 4204 16 . . . cord-006870-f5w6fw6q 4205 1 Meningiomas Meningiomas NNP cord-006870-f5w6fw6q 4205 2 are be VBP cord-006870-f5w6fw6q 4205 3 often often RB cord-006870-f5w6fw6q 4205 4 benign benign JJ cord-006870-f5w6fw6q 4205 5 and and CC cord-006870-f5w6fw6q 4205 6 mostly mostly RB cord-006870-f5w6fw6q 4205 7 asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 4205 8 , , , cord-006870-f5w6fw6q 4205 9 and and CC cord-006870-f5w6fw6q 4205 10 the the DT cord-006870-f5w6fw6q 4205 11 treatment treatment NN cord-006870-f5w6fw6q 4205 12 approaches approach NNS cord-006870-f5w6fw6q 4205 13 may may MD cord-006870-f5w6fw6q 4205 14 include include VB cord-006870-f5w6fw6q 4205 15 open open JJ cord-006870-f5w6fw6q 4205 16 surgical surgical JJ cord-006870-f5w6fw6q 4205 17 resection resection NN cord-006870-f5w6fw6q 4205 18 , , , cord-006870-f5w6fw6q 4205 19 radiosurgery radiosurgery NN cord-006870-f5w6fw6q 4205 20 , , , cord-006870-f5w6fw6q 4205 21 and/or and/or CC cord-006870-f5w6fw6q 4205 22 watchful watchful JJ cord-006870-f5w6fw6q 4205 23 waiting waiting NN cord-006870-f5w6fw6q 4205 24 . . . cord-006870-f5w6fw6q 4206 1 Reported report VBN cord-006870-f5w6fw6q 4206 2 morbidity morbidity NN cord-006870-f5w6fw6q 4206 3 and and CC cord-006870-f5w6fw6q 4206 4 mortality mortality NN cord-006870-f5w6fw6q 4206 5 rates rate NNS cord-006870-f5w6fw6q 4206 6 for for IN cord-006870-f5w6fw6q 4206 7 elderly elderly JJ cord-006870-f5w6fw6q 4206 8 patients patient NNS cord-006870-f5w6fw6q 4206 9 undergoing undergo VBG cord-006870-f5w6fw6q 4206 10 meningioma meningioma NN cord-006870-f5w6fw6q 4206 11 resection resection NN cord-006870-f5w6fw6q 4206 12 vary vary VBP cord-006870-f5w6fw6q 4206 13 widely widely RB cord-006870-f5w6fw6q 4206 14 . . . cord-006870-f5w6fw6q 4207 1 We -PRON- PRP cord-006870-f5w6fw6q 4207 2 sought seek VBD cord-006870-f5w6fw6q 4207 3 to to TO cord-006870-f5w6fw6q 4207 4 investigate investigate VB cord-006870-f5w6fw6q 4207 5 mortality mortality NN cord-006870-f5w6fw6q 4207 6 rates rate NNS cord-006870-f5w6fw6q 4207 7 for for IN cord-006870-f5w6fw6q 4207 8 elderly elderly JJ cord-006870-f5w6fw6q 4207 9 patients patient NNS cord-006870-f5w6fw6q 4207 10 undergoing undergo VBG cord-006870-f5w6fw6q 4207 11 craniotomy craniotomy NN cord-006870-f5w6fw6q 4207 12 for for IN cord-006870-f5w6fw6q 4207 13 meningioma meningioma NN cord-006870-f5w6fw6q 4207 14 resection resection NN cord-006870-f5w6fw6q 4207 15 using use VBG cord-006870-f5w6fw6q 4207 16 the the DT cord-006870-f5w6fw6q 4207 17 Nationwide Nationwide NNP cord-006870-f5w6fw6q 4207 18 Inpatient Inpatient NNP cord-006870-f5w6fw6q 4207 19 Sample Sample NNP cord-006870-f5w6fw6q 4207 20 ( ( -LRB- cord-006870-f5w6fw6q 4207 21 NIS NIS NNP cord-006870-f5w6fw6q 4207 22 ) ) -RRB- cord-006870-f5w6fw6q 4207 23 . . . cord-006870-f5w6fw6q 4208 1 The the DT cord-006870-f5w6fw6q 4208 2 NIS NIS NNP cord-006870-f5w6fw6q 4208 3 datasets dataset NNS cord-006870-f5w6fw6q 4208 4 from from IN cord-006870-f5w6fw6q 4208 5 2003 2003 CD cord-006870-f5w6fw6q 4208 6 to to IN cord-006870-f5w6fw6q 4208 7 2013 2013 CD cord-006870-f5w6fw6q 4208 8 were be VBD cord-006870-f5w6fw6q 4208 9 used use VBN cord-006870-f5w6fw6q 4208 10 to to TO cord-006870-f5w6fw6q 4208 11 identify identify VB cord-006870-f5w6fw6q 4208 12 patient patient JJ cord-006870-f5w6fw6q 4208 13 admissions admission NNS cord-006870-f5w6fw6q 4208 14 for for IN cord-006870-f5w6fw6q 4208 15 meningioma meningioma NN cord-006870-f5w6fw6q 4208 16 resection resection NN cord-006870-f5w6fw6q 4208 17 based base VBN cord-006870-f5w6fw6q 4208 18 on on IN cord-006870-f5w6fw6q 4208 19 the the DT cord-006870-f5w6fw6q 4208 20 ICD-9-CM ICD-9-CM NNP cord-006870-f5w6fw6q 4208 21 code code NN cord-006870-f5w6fw6q 4208 22 01.51 01.51 CD cord-006870-f5w6fw6q 4208 23 . . . cord-006870-f5w6fw6q 4209 1 Age age NN cord-006870-f5w6fw6q 4209 2 categories category NNS cord-006870-f5w6fw6q 4209 3 were be VBD cord-006870-f5w6fw6q 4209 4 defined define VBN cord-006870-f5w6fw6q 4209 5 as as IN cord-006870-f5w6fw6q 4209 6 70 70 CD cord-006870-f5w6fw6q 4209 7 years year NNS cord-006870-f5w6fw6q 4209 8 of of IN cord-006870-f5w6fw6q 4209 9 age age NN cord-006870-f5w6fw6q 4209 10 . . . cord-006870-f5w6fw6q 4210 1 Primary primary JJ cord-006870-f5w6fw6q 4210 2 outcomes outcome NNS cord-006870-f5w6fw6q 4210 3 were be VBD cord-006870-f5w6fw6q 4210 4 in in IN cord-006870-f5w6fw6q 4210 5 - - HYPH cord-006870-f5w6fw6q 4210 6 hospital hospital NN cord-006870-f5w6fw6q 4210 7 mortality mortality NN cord-006870-f5w6fw6q 4210 8 , , , cord-006870-f5w6fw6q 4210 9 poor poor JJ cord-006870-f5w6fw6q 4210 10 outcomes outcome NNS cord-006870-f5w6fw6q 4210 11 ( ( -LRB- cord-006870-f5w6fw6q 4210 12 defined define VBN cord-006870-f5w6fw6q 4210 13 as as IN cord-006870-f5w6fw6q 4210 14 death death NN cord-006870-f5w6fw6q 4210 15 or or CC cord-006870-f5w6fw6q 4210 16 discharge discharge NN cord-006870-f5w6fw6q 4210 17 to to IN cord-006870-f5w6fw6q 4210 18 a a DT cord-006870-f5w6fw6q 4210 19 facility facility NN cord-006870-f5w6fw6q 4210 20 other other JJ cord-006870-f5w6fw6q 4210 21 than than IN cord-006870-f5w6fw6q 4210 22 home home NN cord-006870-f5w6fw6q 4210 23 ) ) -RRB- cord-006870-f5w6fw6q 4210 24 , , , cord-006870-f5w6fw6q 4210 25 cost cost NN cord-006870-f5w6fw6q 4210 26 and and CC cord-006870-f5w6fw6q 4210 27 length length NN cord-006870-f5w6fw6q 4210 28 of of IN cord-006870-f5w6fw6q 4210 29 hospitalization hospitalization NN cord-006870-f5w6fw6q 4210 30 . . . cord-006870-f5w6fw6q 4211 1 A a DT cord-006870-f5w6fw6q 4211 2 total total NN cord-006870-f5w6fw6q 4211 3 of of IN cord-006870-f5w6fw6q 4211 4 24,953 24,953 CD cord-006870-f5w6fw6q 4211 5 patients patient NNS cord-006870-f5w6fw6q 4211 6 were be VBD cord-006870-f5w6fw6q 4211 7 identified identify VBN cord-006870-f5w6fw6q 4211 8 who who WP cord-006870-f5w6fw6q 4211 9 underwent undergo VBD cord-006870-f5w6fw6q 4211 10 meningioma meningioma NN cord-006870-f5w6fw6q 4211 11 resection resection NN cord-006870-f5w6fw6q 4211 12 during during IN cord-006870-f5w6fw6q 4211 13 2003 2003 CD cord-006870-f5w6fw6q 4211 14 - - SYM cord-006870-f5w6fw6q 4211 15 2013 2013 CD cord-006870-f5w6fw6q 4211 16 of of IN cord-006870-f5w6fw6q 4211 17 which which WDT cord-006870-f5w6fw6q 4211 18 20.4 20.4 CD cord-006870-f5w6fw6q 4211 19 % % NN cord-006870-f5w6fw6q 4211 20 were be VBD cord-006870-f5w6fw6q 4211 21 elderly elderly JJ cord-006870-f5w6fw6q 4211 22 ( ( -LRB- cord-006870-f5w6fw6q 4211 23 > > NFP cord-006870-f5w6fw6q 4211 24 70 70 CD cord-006870-f5w6fw6q 4211 25 years year NNS cord-006870-f5w6fw6q 4211 26 ) ) -RRB- cord-006870-f5w6fw6q 4211 27 . . . cord-006870-f5w6fw6q 4212 1 Each each DT cord-006870-f5w6fw6q 4212 2 of of IN cord-006870-f5w6fw6q 4212 3 the the DT cord-006870-f5w6fw6q 4212 4 primary primary JJ cord-006870-f5w6fw6q 4212 5 outcomes outcome NNS cord-006870-f5w6fw6q 4212 6 was be VBD cord-006870-f5w6fw6q 4212 7 heavily heavily RB cord-006870-f5w6fw6q 4212 8 influenced influence VBN cord-006870-f5w6fw6q 4212 9 by by IN cord-006870-f5w6fw6q 4212 10 the the DT cord-006870-f5w6fw6q 4212 11 advancing advance VBG cord-006870-f5w6fw6q 4212 12 age age NN cord-006870-f5w6fw6q 4212 13 . . . cord-006870-f5w6fw6q 4213 1 In in IN cord-006870-f5w6fw6q 4213 2 - - HYPH cord-006870-f5w6fw6q 4213 3 hospital hospital NN cord-006870-f5w6fw6q 4213 4 mortality mortality NN cord-006870-f5w6fw6q 4213 5 was be VBD cord-006870-f5w6fw6q 4213 6 higher high JJR cord-006870-f5w6fw6q 4213 7 in in IN cord-006870-f5w6fw6q 4213 8 the the DT cord-006870-f5w6fw6q 4213 9 elderly elderly JJ cord-006870-f5w6fw6q 4213 10 as as IN cord-006870-f5w6fw6q 4213 11 compared compare VBN cord-006870-f5w6fw6q 4213 12 to to IN cord-006870-f5w6fw6q 4213 13 the the DT cord-006870-f5w6fw6q 4213 14 younger young JJR cord-006870-f5w6fw6q 4213 15 patients patient NNS cord-006870-f5w6fw6q 4213 16 ( ( -LRB- cord-006870-f5w6fw6q 4213 17 3.5 3.5 CD cord-006870-f5w6fw6q 4213 18 % % NN cord-006870-f5w6fw6q 4213 19 vs vs IN cord-006870-f5w6fw6q 4213 20 1 1 CD cord-006870-f5w6fw6q 4213 21 % % NN cord-006870-f5w6fw6q 4213 22 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4213 23 ) ) -RRB- cord-006870-f5w6fw6q 4213 24 , , , cord-006870-f5w6fw6q 4213 25 as as IN cord-006870-f5w6fw6q 4213 26 was be VBD cord-006870-f5w6fw6q 4213 27 the the DT cord-006870-f5w6fw6q 4213 28 rate rate NN cord-006870-f5w6fw6q 4213 29 of of IN cord-006870-f5w6fw6q 4213 30 a a DT cord-006870-f5w6fw6q 4213 31 poor poor JJ cord-006870-f5w6fw6q 4213 32 outcome outcome NN cord-006870-f5w6fw6q 4213 33 ( ( -LRB- cord-006870-f5w6fw6q 4213 34 64.8 64.8 CD cord-006870-f5w6fw6q 4213 35 % % NN cord-006870-f5w6fw6q 4213 36 vs vs IN cord-006870-f5w6fw6q 4213 37 28.1 28.1 CD cord-006870-f5w6fw6q 4213 38 % % NN cord-006870-f5w6fw6q 4213 39 , , , cord-006870-f5w6fw6q 4213 40 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4213 41 ) ) -RRB- cord-006870-f5w6fw6q 4213 42 . . . cord-006870-f5w6fw6q 4214 1 Elderly elderly JJ cord-006870-f5w6fw6q 4214 2 patients patient NNS cord-006870-f5w6fw6q 4214 3 also also RB cord-006870-f5w6fw6q 4214 4 had have VBD cord-006870-f5w6fw6q 4214 5 a a DT cord-006870-f5w6fw6q 4214 6 higher high JJR cord-006870-f5w6fw6q 4214 7 cost cost NN cord-006870-f5w6fw6q 4214 8 ( ( -LRB- cord-006870-f5w6fw6q 4214 9 $ $ $ cord-006870-f5w6fw6q 4214 10 104425 104425 CD cord-006870-f5w6fw6q 4214 11 vs vs IN cord-006870-f5w6fw6q 4214 12 $ $ $ cord-006870-f5w6fw6q 4214 13 96012 96012 CD cord-006870-f5w6fw6q 4214 14 , , , cord-006870-f5w6fw6q 4214 15 p=0.013 p=0.013 NN cord-006870-f5w6fw6q 4214 16 ) ) -RRB- cord-006870-f5w6fw6q 4214 17 and and CC cord-006870-f5w6fw6q 4214 18 increased increase VBN cord-006870-f5w6fw6q 4214 19 length length NN cord-006870-f5w6fw6q 4214 20 of of IN cord-006870-f5w6fw6q 4214 21 hospitalization hospitalization NN cord-006870-f5w6fw6q 4214 22 ( ( -LRB- cord-006870-f5w6fw6q 4214 23 8.9 8.9 CD cord-006870-f5w6fw6q 4214 24 vs vs IN cord-006870-f5w6fw6q 4214 25 6.8 6.8 CD cord-006870-f5w6fw6q 4214 26 days day NNS cord-006870-f5w6fw6q 4214 27 , , , cord-006870-f5w6fw6q 4214 28 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4214 29 ) ) -RRB- cord-006870-f5w6fw6q 4214 30 . . . cord-006870-f5w6fw6q 4215 1 In in IN cord-006870-f5w6fw6q 4215 2 our -PRON- PRP$ cord-006870-f5w6fw6q 4215 3 study study NN cord-006870-f5w6fw6q 4215 4 , , , cord-006870-f5w6fw6q 4215 5 age age NN cord-006870-f5w6fw6q 4215 6 > > XX cord-006870-f5w6fw6q 4215 7 70 70 CD cord-006870-f5w6fw6q 4215 8 was be VBD cord-006870-f5w6fw6q 4215 9 strongly strongly RB cord-006870-f5w6fw6q 4215 10 associated associate VBN cord-006870-f5w6fw6q 4215 11 with with IN cord-006870-f5w6fw6q 4215 12 adverse adverse JJ cord-006870-f5w6fw6q 4215 13 outcomes outcome NNS cord-006870-f5w6fw6q 4215 14 after after IN cord-006870-f5w6fw6q 4215 15 meningioma meningioma NN cord-006870-f5w6fw6q 4215 16 resection resection NN cord-006870-f5w6fw6q 4215 17 . . . cord-006870-f5w6fw6q 4216 1 This this DT cord-006870-f5w6fw6q 4216 2 increased increase VBN cord-006870-f5w6fw6q 4216 3 risk risk NN cord-006870-f5w6fw6q 4216 4 should should MD cord-006870-f5w6fw6q 4216 5 be be VB cord-006870-f5w6fw6q 4216 6 taken take VBN cord-006870-f5w6fw6q 4216 7 into into IN cord-006870-f5w6fw6q 4216 8 account account NN cord-006870-f5w6fw6q 4216 9 when when WRB cord-006870-f5w6fw6q 4216 10 considering consider VBG cord-006870-f5w6fw6q 4216 11 surgical surgical JJ cord-006870-f5w6fw6q 4216 12 intervention intervention NN cord-006870-f5w6fw6q 4216 13 in in IN cord-006870-f5w6fw6q 4216 14 this this DT cord-006870-f5w6fw6q 4216 15 subgroup subgroup NN cord-006870-f5w6fw6q 4216 16 . . . cord-006870-f5w6fw6q 4217 1 Based base VBN cord-006870-f5w6fw6q 4217 2 on on IN cord-006870-f5w6fw6q 4217 3 this this DT cord-006870-f5w6fw6q 4217 4 study study NN cord-006870-f5w6fw6q 4217 5 , , , cord-006870-f5w6fw6q 4217 6 closer close RBR cord-006870-f5w6fw6q 4217 7 perioperative perioperative JJ cord-006870-f5w6fw6q 4217 8 monitoring monitoring NN cord-006870-f5w6fw6q 4217 9 may may MD cord-006870-f5w6fw6q 4217 10 be be VB cord-006870-f5w6fw6q 4217 11 warranted warrant VBN cord-006870-f5w6fw6q 4217 12 in in IN cord-006870-f5w6fw6q 4217 13 the the DT cord-006870-f5w6fw6q 4217 14 elderly elderly JJ cord-006870-f5w6fw6q 4217 15 patient patient NN cord-006870-f5w6fw6q 4217 16 subgroup subgroup NN cord-006870-f5w6fw6q 4217 17 . . . cord-006870-f5w6fw6q 4218 1 Treatment treatment NN cord-006870-f5w6fw6q 4218 2 with with IN cord-006870-f5w6fw6q 4218 3 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 4218 4 improves improve VBZ cord-006870-f5w6fw6q 4218 5 outcomes outcome NNS cord-006870-f5w6fw6q 4218 6 in in IN cord-006870-f5w6fw6q 4218 7 cerebral cerebral JJ cord-006870-f5w6fw6q 4218 8 venous venous JJ cord-006870-f5w6fw6q 4218 9 - - HYPH cord-006870-f5w6fw6q 4218 10 sinus sinus NN cord-006870-f5w6fw6q 4218 11 thrombosis thrombosis NN cord-006870-f5w6fw6q 4218 12 ( ( -LRB- cord-006870-f5w6fw6q 4218 13 CVST CVST NNP cord-006870-f5w6fw6q 4218 14 ) ) -RRB- cord-006870-f5w6fw6q 4218 15 . . . cord-006870-f5w6fw6q 4219 1 However however RB cord-006870-f5w6fw6q 4219 2 patients patient NNS cord-006870-f5w6fw6q 4219 3 who who WP cord-006870-f5w6fw6q 4219 4 develop develop VBP cord-006870-f5w6fw6q 4219 5 extensive extensive JJ cord-006870-f5w6fw6q 4219 6 infarcts infarct NNS cord-006870-f5w6fw6q 4219 7 and/or and/or CC cord-006870-f5w6fw6q 4219 8 intracerebral intracerebral NN cord-006870-f5w6fw6q 4219 9 - - HYPH cord-006870-f5w6fw6q 4219 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4219 11 with with IN cord-006870-f5w6fw6q 4219 12 mass mass JJ cord-006870-f5w6fw6q 4219 13 - - HYPH cord-006870-f5w6fw6q 4219 14 effect effect NN cord-006870-f5w6fw6q 4219 15 resulting result VBG cord-006870-f5w6fw6q 4219 16 in in IN cord-006870-f5w6fw6q 4219 17 comatose comatose JJ cord-006870-f5w6fw6q 4219 18 - - HYPH cord-006870-f5w6fw6q 4219 19 state state NN cord-006870-f5w6fw6q 4219 20 are be VBP cord-006870-f5w6fw6q 4219 21 at at IN cord-006870-f5w6fw6q 4219 22 risk risk NN cord-006870-f5w6fw6q 4219 23 of of IN cord-006870-f5w6fw6q 4219 24 poor poor JJ cord-006870-f5w6fw6q 4219 25 outcomes outcome NNS cord-006870-f5w6fw6q 4219 26 , , , cord-006870-f5w6fw6q 4219 27 and and CC cord-006870-f5w6fw6q 4219 28 may may MD cord-006870-f5w6fw6q 4219 29 benefit benefit VB cord-006870-f5w6fw6q 4219 30 from from IN cord-006870-f5w6fw6q 4219 31 decompressive decompressive JJ cord-006870-f5w6fw6q 4219 32 craniectomy craniectomy NNP cord-006870-f5w6fw6q 4219 33 ( ( -LRB- cord-006870-f5w6fw6q 4219 34 DC DC NNP cord-006870-f5w6fw6q 4219 35 ) ) -RRB- cord-006870-f5w6fw6q 4219 36 . . . cord-006870-f5w6fw6q 4220 1 We -PRON- PRP cord-006870-f5w6fw6q 4220 2 evaluated evaluate VBD cord-006870-f5w6fw6q 4220 3 the the DT cord-006870-f5w6fw6q 4220 4 role role NN cord-006870-f5w6fw6q 4220 5 of of IN cord-006870-f5w6fw6q 4220 6 DC DC NNP cord-006870-f5w6fw6q 4220 7 in in IN cord-006870-f5w6fw6q 4220 8 the the DT cord-006870-f5w6fw6q 4220 9 management management NN cord-006870-f5w6fw6q 4220 10 of of IN cord-006870-f5w6fw6q 4220 11 malignant malignant JJ cord-006870-f5w6fw6q 4220 12 CVST CVST NNP cord-006870-f5w6fw6q 4220 13 and and CC cord-006870-f5w6fw6q 4220 14 its -PRON- PRP$ cord-006870-f5w6fw6q 4220 15 impact impact NN cord-006870-f5w6fw6q 4220 16 on on IN cord-006870-f5w6fw6q 4220 17 outcomes outcome NNS cord-006870-f5w6fw6q 4220 18 . . . cord-006870-f5w6fw6q 4221 1 Literature literature NN cord-006870-f5w6fw6q 4221 2 - - HYPH cord-006870-f5w6fw6q 4221 3 search search NN cord-006870-f5w6fw6q 4221 4 was be VBD cord-006870-f5w6fw6q 4221 5 conducted conduct VBN cord-006870-f5w6fw6q 4221 6 on on IN cord-006870-f5w6fw6q 4221 7 Pubmed Pubmed NNP cord-006870-f5w6fw6q 4221 8 and and CC cord-006870-f5w6fw6q 4221 9 Google Google NNP cord-006870-f5w6fw6q 4221 10 - - HYPH cord-006870-f5w6fw6q 4221 11 Scholar Scholar NNP cord-006870-f5w6fw6q 4221 12 using use VBG cord-006870-f5w6fw6q 4221 13 terms term NNS cord-006870-f5w6fw6q 4221 14 " " `` cord-006870-f5w6fw6q 4221 15 Craniectomy Craniectomy NNP cord-006870-f5w6fw6q 4221 16 " " '' cord-006870-f5w6fw6q 4221 17 , , , cord-006870-f5w6fw6q 4221 18 and and CC cord-006870-f5w6fw6q 4221 19 " " `` cord-006870-f5w6fw6q 4221 20 cerebral cerebral JJ cord-006870-f5w6fw6q 4221 21 venous venous JJ cord-006870-f5w6fw6q 4221 22 - - HYPH cord-006870-f5w6fw6q 4221 23 sinus sinus NN cord-006870-f5w6fw6q 4221 24 thrombosis thrombosis NN cord-006870-f5w6fw6q 4221 25 " " '' cord-006870-f5w6fw6q 4221 26 . . . cord-006870-f5w6fw6q 4222 1 We -PRON- PRP cord-006870-f5w6fw6q 4222 2 included include VBD cord-006870-f5w6fw6q 4222 3 studies study NNS cord-006870-f5w6fw6q 4222 4 that that WDT cord-006870-f5w6fw6q 4222 5 described describe VBD cord-006870-f5w6fw6q 4222 6 any any DT cord-006870-f5w6fw6q 4222 7 number number NN cord-006870-f5w6fw6q 4222 8 of of IN cord-006870-f5w6fw6q 4222 9 patients patient NNS cord-006870-f5w6fw6q 4222 10 with with IN cord-006870-f5w6fw6q 4222 11 CVST CVST NNP cord-006870-f5w6fw6q 4222 12 who who WP cord-006870-f5w6fw6q 4222 13 underwent undergo VBD cord-006870-f5w6fw6q 4222 14 DC DC NNP cord-006870-f5w6fw6q 4222 15 after after IN cord-006870-f5w6fw6q 4222 16 clinical clinical JJ cord-006870-f5w6fw6q 4222 17 deterioration deterioration NN cord-006870-f5w6fw6q 4222 18 and and CC cord-006870-f5w6fw6q 4222 19 reported report VBD cord-006870-f5w6fw6q 4222 20 their -PRON- PRP$ cord-006870-f5w6fw6q 4222 21 outcomes outcome NNS cord-006870-f5w6fw6q 4222 22 . . . cord-006870-f5w6fw6q 4223 1 A a DT cord-006870-f5w6fw6q 4223 2 similar similar JJ cord-006870-f5w6fw6q 4223 3 search search NN cord-006870-f5w6fw6q 4223 4 strategy strategy NN cord-006870-f5w6fw6q 4223 5 identified identify VBD cord-006870-f5w6fw6q 4223 6 patients patient NNS cord-006870-f5w6fw6q 4223 7 from from IN cord-006870-f5w6fw6q 4223 8 our -PRON- PRP$ cord-006870-f5w6fw6q 4223 9 institute institute NN cord-006870-f5w6fw6q 4223 10 . . . cord-006870-f5w6fw6q 4224 1 Outcomes outcome NNS cord-006870-f5w6fw6q 4224 2 were be VBD cord-006870-f5w6fw6q 4224 3 reported report VBN cord-006870-f5w6fw6q 4224 4 as as IN cord-006870-f5w6fw6q 4224 5 modified modify VBN cord-006870-f5w6fw6q 4224 6 - - HYPH cord-006870-f5w6fw6q 4224 7 Rankin Rankin NNP cord-006870-f5w6fw6q 4224 8 Scale scale NN cord-006870-f5w6fw6q 4224 9 ( ( -LRB- cord-006870-f5w6fw6q 4224 10 mRS mRS : cord-006870-f5w6fw6q 4224 11 ) ) -RRB- cord-006870-f5w6fw6q 4224 12 or or CC cord-006870-f5w6fw6q 4224 13 Glasgow Glasgow NNP cord-006870-f5w6fw6q 4224 14 - - HYPH cord-006870-f5w6fw6q 4224 15 Outcomes Outcomes NNP cord-006870-f5w6fw6q 4224 16 Scale scale NN cord-006870-f5w6fw6q 4224 17 ( ( -LRB- cord-006870-f5w6fw6q 4224 18 GOS GOS NNP cord-006870-f5w6fw6q 4224 19 ) ) -RRB- cord-006870-f5w6fw6q 4224 20 and and CC cord-006870-f5w6fw6q 4224 21 were be VBD cord-006870-f5w6fw6q 4224 22 classified classify VBN cord-006870-f5w6fw6q 4224 23 as as IN cord-006870-f5w6fw6q 4224 24 favorable favorable JJ cord-006870-f5w6fw6q 4224 25 ( ( -LRB- cord-006870-f5w6fw6q 4224 26 mRS mRS `` cord-006870-f5w6fw6q 4224 27 0 0 CD cord-006870-f5w6fw6q 4224 28 - - SYM cord-006870-f5w6fw6q 4224 29 3 3 CD cord-006870-f5w6fw6q 4224 30 ; ; : cord-006870-f5w6fw6q 4224 31 GOS GOS NNP cord-006870-f5w6fw6q 4224 32 4 4 CD cord-006870-f5w6fw6q 4224 33 - - SYM cord-006870-f5w6fw6q 4224 34 5 5 CD cord-006870-f5w6fw6q 4224 35 ) ) -RRB- cord-006870-f5w6fw6q 4224 36 , , , cord-006870-f5w6fw6q 4224 37 or or CC cord-006870-f5w6fw6q 4224 38 unfavorable unfavorable JJ cord-006870-f5w6fw6q 4224 39 ( ( -LRB- cord-006870-f5w6fw6q 4224 40 mRS mrs PRP$ cord-006870-f5w6fw6q 4224 41 4 4 CD cord-006870-f5w6fw6q 4224 42 - - SYM cord-006870-f5w6fw6q 4224 43 6 6 CD cord-006870-f5w6fw6q 4224 44 ; ; : cord-006870-f5w6fw6q 4224 45 GOS GOS NNP cord-006870-f5w6fw6q 4224 46 1 1 CD cord-006870-f5w6fw6q 4224 47 - - SYM cord-006870-f5w6fw6q 4224 48 3 3 CD cord-006870-f5w6fw6q 4224 49 ) ) -RRB- cord-006870-f5w6fw6q 4224 50 . . . cord-006870-f5w6fw6q 4225 1 A a DT cord-006870-f5w6fw6q 4225 2 total total NN cord-006870-f5w6fw6q 4225 3 of of IN cord-006870-f5w6fw6q 4225 4 296 296 CD cord-006870-f5w6fw6q 4225 5 patients patient NNS cord-006870-f5w6fw6q 4225 6 ( ( -LRB- cord-006870-f5w6fw6q 4225 7 females=164 females=164 NNP cord-006870-f5w6fw6q 4225 8 ; ; : cord-006870-f5w6fw6q 4225 9 males=74 males=74 NNP cord-006870-f5w6fw6q 4225 10 ; ; : cord-006870-f5w6fw6q 4225 11 unknown=58 unknown=58 NNP cord-006870-f5w6fw6q 4225 12 ) ) -RRB- cord-006870-f5w6fw6q 4225 13 who who WP cord-006870-f5w6fw6q 4225 14 underwent undergo VBD cord-006870-f5w6fw6q 4225 15 DC DC NNP cord-006870-f5w6fw6q 4225 16 for for IN cord-006870-f5w6fw6q 4225 17 malignant malignant JJ cord-006870-f5w6fw6q 4225 18 - - : cord-006870-f5w6fw6q 4225 19 CVST CVST NNP cord-006870-f5w6fw6q 4225 20 were be VBD cord-006870-f5w6fw6q 4225 21 identified identify VBN cord-006870-f5w6fw6q 4225 22 from from IN cord-006870-f5w6fw6q 4225 23 29 29 CD cord-006870-f5w6fw6q 4225 24 studies study NNS cord-006870-f5w6fw6q 4225 25 ( ( -LRB- cord-006870-f5w6fw6q 4225 26 n=281 n=281 CD cord-006870-f5w6fw6q 4225 27 ) ) -RRB- cord-006870-f5w6fw6q 4225 28 and and CC cord-006870-f5w6fw6q 4225 29 our -PRON- PRP$ cord-006870-f5w6fw6q 4225 30 institute institute NN cord-006870-f5w6fw6q 4225 31 ( ( -LRB- cord-006870-f5w6fw6q 4225 32 n=15 n=15 NNP cord-006870-f5w6fw6q 4225 33 ) ) -RRB- cord-006870-f5w6fw6q 4225 34 . . . cord-006870-f5w6fw6q 4226 1 Age Age NNP cord-006870-f5w6fw6q 4226 2 and and CC cord-006870-f5w6fw6q 4226 3 GCS GCS NNP cord-006870-f5w6fw6q 4226 4 ( ( -LRB- cord-006870-f5w6fw6q 4226 5 before before IN cord-006870-f5w6fw6q 4226 6 - - HYPH cord-006870-f5w6fw6q 4226 7 surgery surgery NN cord-006870-f5w6fw6q 4226 8 ) ) -RRB- cord-006870-f5w6fw6q 4226 9 were be VBD cord-006870-f5w6fw6q 4226 10 only only RB cord-006870-f5w6fw6q 4226 11 available available JJ cord-006870-f5w6fw6q 4226 12 from from IN cord-006870-f5w6fw6q 4226 13 125 125 CD cord-006870-f5w6fw6q 4226 14 patients patient NNS cord-006870-f5w6fw6q 4226 15 , , , cord-006870-f5w6fw6q 4226 16 with with IN cord-006870-f5w6fw6q 4226 17 mean mean NN cord-006870-f5w6fw6q 4226 18 - - HYPH cord-006870-f5w6fw6q 4226 19 age age NN cord-006870-f5w6fw6q 4226 20 36.74 36.74 CD cord-006870-f5w6fw6q 4226 21 ( ( -LRB- cord-006870-f5w6fw6q 4226 22 + + CC cord-006870-f5w6fw6q 4226 23 /-13.52 /-13.52 . cord-006870-f5w6fw6q 4226 24 ) ) -RRB- cord-006870-f5w6fw6q 4227 1 and and CC cord-006870-f5w6fw6q 4227 2 mean mean JJ cord-006870-f5w6fw6q 4227 3 - - HYPH cord-006870-f5w6fw6q 4227 4 GCS GCS NNP cord-006870-f5w6fw6q 4227 5 7.58 7.58 CD cord-006870-f5w6fw6q 4227 6 ( ( -LRB- cord-006870-f5w6fw6q 4227 7 + + CD cord-006870-f5w6fw6q 4227 8 /-3.03 /-3.03 NNP cord-006870-f5w6fw6q 4227 9 ) ) -RRB- cord-006870-f5w6fw6q 4227 10 . . . cord-006870-f5w6fw6q 4228 1 199 199 CD cord-006870-f5w6fw6q 4228 2 patients patient NNS cord-006870-f5w6fw6q 4228 3 ( ( -LRB- cord-006870-f5w6fw6q 4228 4 67.2 67.2 CD cord-006870-f5w6fw6q 4228 5 % % NN cord-006870-f5w6fw6q 4228 6 ) ) -RRB- cord-006870-f5w6fw6q 4228 7 had have VBD cord-006870-f5w6fw6q 4228 8 favorable favorable JJ cord-006870-f5w6fw6q 4228 9 - - HYPH cord-006870-f5w6fw6q 4228 10 outcomes outcome NNS cord-006870-f5w6fw6q 4228 11 , , , cord-006870-f5w6fw6q 4228 12 while while IN cord-006870-f5w6fw6q 4228 13 63 63 CD cord-006870-f5w6fw6q 4228 14 patients patient NNS cord-006870-f5w6fw6q 4228 15 ( ( -LRB- cord-006870-f5w6fw6q 4228 16 21.3 21.3 CD cord-006870-f5w6fw6q 4228 17 % % NN cord-006870-f5w6fw6q 4228 18 ) ) -RRB- cord-006870-f5w6fw6q 4228 19 died die VBD cord-006870-f5w6fw6q 4228 20 . . . cord-006870-f5w6fw6q 4229 1 In in IN cord-006870-f5w6fw6q 4229 2 the the DT cord-006870-f5w6fw6q 4229 3 multi multi JJ cord-006870-f5w6fw6q 4229 4 - - JJ cord-006870-f5w6fw6q 4229 5 variate variate JJ cord-006870-f5w6fw6q 4229 6 binarylogistic binarylogistic JJ cord-006870-f5w6fw6q 4229 7 regression regression NN cord-006870-f5w6fw6q 4229 8 - - HYPH cord-006870-f5w6fw6q 4229 9 model model NN cord-006870-f5w6fw6q 4229 10 , , , cord-006870-f5w6fw6q 4229 11 every every DT cord-006870-f5w6fw6q 4229 12 point point NN cord-006870-f5w6fw6q 4229 13 - - HYPH cord-006870-f5w6fw6q 4229 14 drop drop NN cord-006870-f5w6fw6q 4229 15 in in IN cord-006870-f5w6fw6q 4229 16 GCS GCS NNP cord-006870-f5w6fw6q 4229 17 decreased decrease VBD cord-006870-f5w6fw6q 4229 18 the the DT cord-006870-f5w6fw6q 4229 19 odds odd NNS cord-006870-f5w6fw6q 4229 20 of of IN cord-006870-f5w6fw6q 4229 21 favorable favorable JJ cord-006870-f5w6fw6q 4229 22 - - HYPH cord-006870-f5w6fw6q 4229 23 outcomes outcome NNS cord-006870-f5w6fw6q 4229 24 by by IN cord-006870-f5w6fw6q 4229 25 0.57times 0.57times CD cord-006870-f5w6fw6q 4230 1 ( ( -LRB- cord-006870-f5w6fw6q 4230 2 p<0.001 p<0.001 NNS cord-006870-f5w6fw6q 4230 3 ; ; : cord-006870-f5w6fw6q 4230 4 95%CI=0.423 95%ci=0.423 CD cord-006870-f5w6fw6q 4230 5 - - HYPH cord-006870-f5w6fw6q 4230 6 0.775 0.775 CD cord-006870-f5w6fw6q 4230 7 ) ) -RRB- cord-006870-f5w6fw6q 4230 8 , , , cord-006870-f5w6fw6q 4230 9 and and CC cord-006870-f5w6fw6q 4230 10 survival survival NN cord-006870-f5w6fw6q 4230 11 by by IN cord-006870-f5w6fw6q 4230 12 0.58-times 0.58-times NNP cord-006870-f5w6fw6q 4230 13 ( ( -LRB- cord-006870-f5w6fw6q 4230 14 p=0.002 p=0.002 UH cord-006870-f5w6fw6q 4230 15 ; ; : cord-006870-f5w6fw6q 4230 16 95%CI=0.414 95%ci=0.414 CD cord-006870-f5w6fw6q 4230 17 - - HYPH cord-006870-f5w6fw6q 4230 18 0.821 0.821 CD cord-006870-f5w6fw6q 4230 19 ) ) -RRB- cord-006870-f5w6fw6q 4230 20 . . . cord-006870-f5w6fw6q 4231 1 Thrombosis thrombosis NN cord-006870-f5w6fw6q 4231 2 in in IN cord-006870-f5w6fw6q 4231 3 Internal internal JJ cord-006870-f5w6fw6q 4231 4 - - HYPH cord-006870-f5w6fw6q 4231 5 jugular jugular NN cord-006870-f5w6fw6q 4231 6 vein vein NN cord-006870-f5w6fw6q 4231 7 ( ( -LRB- cord-006870-f5w6fw6q 4231 8 IJV ijv NN cord-006870-f5w6fw6q 4231 9 ) ) -RRB- cord-006870-f5w6fw6q 4231 10 ( ( -LRB- cord-006870-f5w6fw6q 4231 11 OR=10.39 OR=10.39 NNP cord-006870-f5w6fw6q 4231 12 ; ; : cord-006870-f5w6fw6q 4231 13 95%CI=1.36 95%ci=1.36 CD cord-006870-f5w6fw6q 4231 14 - - HYPH cord-006870-f5w6fw6q 4231 15 79.30 79.30 CD cord-006870-f5w6fw6q 4231 16 ; ; : cord-006870-f5w6fw6q 4231 17 p=0.024 p=0.024 NNP cord-006870-f5w6fw6q 4231 18 ) ) -RRB- cord-006870-f5w6fw6q 4231 19 and and CC cord-006870-f5w6fw6q 4231 20 Deep deep JJ cord-006870-f5w6fw6q 4231 21 - - HYPH cord-006870-f5w6fw6q 4231 22 cerebral cerebral JJ cord-006870-f5w6fw6q 4231 23 veins vein NNS cord-006870-f5w6fw6q 4231 24 ( ( -LRB- cord-006870-f5w6fw6q 4231 25 DCV dcv NN cord-006870-f5w6fw6q 4231 26 ) ) -RRB- cord-006870-f5w6fw6q 4232 1 ( ( -LRB- cord-006870-f5w6fw6q 4232 2 OR=8.94 or=8.94 NN cord-006870-f5w6fw6q 4232 3 ; ; : cord-006870-f5w6fw6q 4232 4 95%CI=1.33 95%ci=1.33 CD cord-006870-f5w6fw6q 4232 5 - - SYM cord-006870-f5w6fw6q 4232 6 60.17 60.17 CD cord-006870-f5w6fw6q 4232 7 ; ; : cord-006870-f5w6fw6q 4232 8 p=0.024 p=0.024 ADD cord-006870-f5w6fw6q 4232 9 ) ) -RRB- cord-006870-f5w6fw6q 4232 10 predicted predict VBD cord-006870-f5w6fw6q 4232 11 unfavorable unfavorable JJ cord-006870-f5w6fw6q 4232 12 - - HYPH cord-006870-f5w6fw6q 4232 13 outcomes outcome NNS cord-006870-f5w6fw6q 4232 14 . . . cord-006870-f5w6fw6q 4233 1 IJV ijv NN cord-006870-f5w6fw6q 4233 2 - - HYPH cord-006870-f5w6fw6q 4233 3 thrombosis thrombosis NN cord-006870-f5w6fw6q 4233 4 ( ( -LRB- cord-006870-f5w6fw6q 4233 5 OR=10.67 OR=10.67 NNP cord-006870-f5w6fw6q 4233 6 ; ; : cord-006870-f5w6fw6q 4233 7 95%CI=1.07 95%ci=1.07 CD cord-006870-f5w6fw6q 4233 8 - - SYM cord-006870-f5w6fw6q 4233 9 106.86 106.86 CD cord-006870-f5w6fw6q 4233 10 ; ; : cord-006870-f5w6fw6q 4233 11 p=0.044 p=0.044 NNS cord-006870-f5w6fw6q 4233 12 ) ) -RRB- cord-006870-f5w6fw6q 4233 13 and and CC cord-006870-f5w6fw6q 4233 14 DCV dcv NN cord-006870-f5w6fw6q 4233 15 - - HYPH cord-006870-f5w6fw6q 4233 16 thrombosis thrombosis NN cord-006870-f5w6fw6q 4234 1 ( ( -LRB- cord-006870-f5w6fw6q 4234 2 OR=13.5 or=13.5 UH cord-006870-f5w6fw6q 4234 3 ; ; : cord-006870-f5w6fw6q 4234 4 95%CI=1.57 95%ci=1.57 CD cord-006870-f5w6fw6q 4234 5 - - HYPH cord-006870-f5w6fw6q 4234 6 115.82 115.82 CD cord-006870-f5w6fw6q 4234 7 ; ; : cord-006870-f5w6fw6q 4234 8 p=0.018 p=0.018 NNP cord-006870-f5w6fw6q 4234 9 ) ) -RRB- cord-006870-f5w6fw6q 4234 10 also also RB cord-006870-f5w6fw6q 4234 11 predicted predict VBD cord-006870-f5w6fw6q 4234 12 mortality mortality NN cord-006870-f5w6fw6q 4234 13 . . . cord-006870-f5w6fw6q 4235 1 Interestingly interestingly RB cord-006870-f5w6fw6q 4235 2 , , , cord-006870-f5w6fw6q 4235 3 cortical cortical JJ cord-006870-f5w6fw6q 4235 4 - - HYPH cord-006870-f5w6fw6q 4235 5 vein vein NN cord-006870-f5w6fw6q 4235 6 thrombosis thrombosis NN cord-006870-f5w6fw6q 4235 7 was be VBD cord-006870-f5w6fw6q 4235 8 associated associate VBN cord-006870-f5w6fw6q 4235 9 with with IN cord-006870-f5w6fw6q 4235 10 lower low JJR cord-006870-f5w6fw6q 4235 11 odds odd NNS cord-006870-f5w6fw6q 4235 12 of of IN cord-006870-f5w6fw6q 4235 13 unfavorable unfavorable JJ cord-006870-f5w6fw6q 4235 14 outcomes outcome NNS cord-006870-f5w6fw6q 4235 15 ( ( -LRB- cord-006870-f5w6fw6q 4235 16 OR=0.217 or=0.217 NN cord-006870-f5w6fw6q 4235 17 ; ; : cord-006870-f5w6fw6q 4235 18 95%CI=0.051 95%ci=0.051 CD cord-006870-f5w6fw6q 4235 19 - - HYPH cord-006870-f5w6fw6q 4235 20 0.921 0.921 CD cord-006870-f5w6fw6q 4235 21 ; ; : cord-006870-f5w6fw6q 4235 22 p=0.038 p=0.038 NNP cord-006870-f5w6fw6q 4235 23 ) ) -RRB- cord-006870-f5w6fw6q 4235 24 . . . cord-006870-f5w6fw6q 4236 1 Data datum NNS cord-006870-f5w6fw6q 4236 2 regarding regard VBG cord-006870-f5w6fw6q 4236 3 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 4236 4 and and CC cord-006870-f5w6fw6q 4236 5 long long JJ cord-006870-f5w6fw6q 4236 6 - - HYPH cord-006870-f5w6fw6q 4236 7 term term NN cord-006870-f5w6fw6q 4236 8 follow follow NN cord-006870-f5w6fw6q 4236 9 - - HYPH cord-006870-f5w6fw6q 4236 10 up up NN cord-006870-f5w6fw6q 4236 11 were be VBD cord-006870-f5w6fw6q 4236 12 not not RB cord-006870-f5w6fw6q 4236 13 uniformly uniformly RB cord-006870-f5w6fw6q 4236 14 available available JJ cord-006870-f5w6fw6q 4236 15 . . . cord-006870-f5w6fw6q 4237 1 For for IN cord-006870-f5w6fw6q 4237 2 patients patient NNS cord-006870-f5w6fw6q 4237 3 with with IN cord-006870-f5w6fw6q 4237 4 malignant malignant JJ cord-006870-f5w6fw6q 4237 5 - - HYPH cord-006870-f5w6fw6q 4237 6 CVST CVST NNP cord-006870-f5w6fw6q 4237 7 , , , cord-006870-f5w6fw6q 4237 8 craniectomy craniectomy NN cord-006870-f5w6fw6q 4237 9 could could MD cord-006870-f5w6fw6q 4237 10 potentially potentially RB cord-006870-f5w6fw6q 4237 11 improve improve VB cord-006870-f5w6fw6q 4237 12 outcomes outcome NNS cord-006870-f5w6fw6q 4237 13 . . . cord-006870-f5w6fw6q 4238 1 Factors factor NNS cord-006870-f5w6fw6q 4238 2 such such JJ cord-006870-f5w6fw6q 4238 3 as as IN cord-006870-f5w6fw6q 4238 4 GCS GCS NNP cord-006870-f5w6fw6q 4238 5 before before IN cord-006870-f5w6fw6q 4238 6 - - HYPH cord-006870-f5w6fw6q 4238 7 surgery surgery NN cord-006870-f5w6fw6q 4238 8 and and CC cord-006870-f5w6fw6q 4238 9 CVST CVST NNP cord-006870-f5w6fw6q 4238 10 location location NN cord-006870-f5w6fw6q 4238 11 can can MD cord-006870-f5w6fw6q 4238 12 help help VB cord-006870-f5w6fw6q 4238 13 predict predict VB cord-006870-f5w6fw6q 4238 14 outcome outcome NN cord-006870-f5w6fw6q 4238 15 following follow VBG cord-006870-f5w6fw6q 4238 16 DC DC NNP cord-006870-f5w6fw6q 4238 17 and and CC cord-006870-f5w6fw6q 4238 18 aid aid VB cord-006870-f5w6fw6q 4238 19 the the DT cord-006870-f5w6fw6q 4238 20 decision decision NN cord-006870-f5w6fw6q 4238 21 - - HYPH cord-006870-f5w6fw6q 4238 22 making make VBG cord-006870-f5w6fw6q 4238 23 process process NN cord-006870-f5w6fw6q 4238 24 . . . cord-006870-f5w6fw6q 4239 1 A a DT cord-006870-f5w6fw6q 4239 2 multi multi JJ cord-006870-f5w6fw6q 4239 3 - - JJ cord-006870-f5w6fw6q 4239 4 institutional institutional JJ cord-006870-f5w6fw6q 4239 5 observational observational JJ cord-006870-f5w6fw6q 4239 6 cohort cohort NN cord-006870-f5w6fw6q 4239 7 should should MD cord-006870-f5w6fw6q 4239 8 be be VB cord-006870-f5w6fw6q 4239 9 designed design VBN cord-006870-f5w6fw6q 4239 10 to to TO cord-006870-f5w6fw6q 4239 11 prospectively prospectively RB cord-006870-f5w6fw6q 4239 12 evaluate evaluate VB cord-006870-f5w6fw6q 4239 13 predictors predictor NNS cord-006870-f5w6fw6q 4239 14 for for IN cord-006870-f5w6fw6q 4239 15 , , , cord-006870-f5w6fw6q 4239 16 timing timing NN cord-006870-f5w6fw6q 4239 17 of of IN cord-006870-f5w6fw6q 4239 18 , , , cord-006870-f5w6fw6q 4239 19 and and CC cord-006870-f5w6fw6q 4239 20 outcomes outcome NNS cord-006870-f5w6fw6q 4239 21 after after IN cord-006870-f5w6fw6q 4239 22 craniectomy craniectomy NN cord-006870-f5w6fw6q 4239 23 in in IN cord-006870-f5w6fw6q 4239 24 CVST CVST NNP cord-006870-f5w6fw6q 4239 25 . . . cord-006870-f5w6fw6q 4240 1 The the DT cord-006870-f5w6fw6q 4240 2 external external JJ cord-006870-f5w6fw6q 4240 3 ventricular ventricular JJ cord-006870-f5w6fw6q 4240 4 drain drain NN cord-006870-f5w6fw6q 4240 5 ( ( -LRB- cord-006870-f5w6fw6q 4240 6 EVD EVD NNP cord-006870-f5w6fw6q 4240 7 ) ) -RRB- cord-006870-f5w6fw6q 4240 8 is be VBZ cord-006870-f5w6fw6q 4240 9 commonly commonly RB cord-006870-f5w6fw6q 4240 10 used use VBN cord-006870-f5w6fw6q 4240 11 in in IN cord-006870-f5w6fw6q 4240 12 the the DT cord-006870-f5w6fw6q 4240 13 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 4240 14 care care NN cord-006870-f5w6fw6q 4240 15 unit unit NN cord-006870-f5w6fw6q 4240 16 to to TO cord-006870-f5w6fw6q 4240 17 help help VB cord-006870-f5w6fw6q 4240 18 monitor monitor VB cord-006870-f5w6fw6q 4240 19 intracranial intracranial JJ cord-006870-f5w6fw6q 4240 20 pressure pressure NN cord-006870-f5w6fw6q 4240 21 ( ( -LRB- cord-006870-f5w6fw6q 4240 22 ICP ICP NNP cord-006870-f5w6fw6q 4240 23 ) ) -RRB- cord-006870-f5w6fw6q 4240 24 with with IN cord-006870-f5w6fw6q 4240 25 the the DT cord-006870-f5w6fw6q 4240 26 added add VBN cord-006870-f5w6fw6q 4240 27 advantage advantage NN cord-006870-f5w6fw6q 4240 28 of of IN cord-006870-f5w6fw6q 4240 29 therapeutically therapeutically RB cord-006870-f5w6fw6q 4240 30 treating treat VBG cord-006870-f5w6fw6q 4240 31 elevated elevate VBN cord-006870-f5w6fw6q 4240 32 ICP ICP NNP cord-006870-f5w6fw6q 4240 33 by by IN cord-006870-f5w6fw6q 4240 34 diverting divert VBG cord-006870-f5w6fw6q 4240 35 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 4240 36 fluid fluid NN cord-006870-f5w6fw6q 4240 37 ( ( -LRB- cord-006870-f5w6fw6q 4240 38 CSF CSF NNP cord-006870-f5w6fw6q 4240 39 ) ) -RRB- cord-006870-f5w6fw6q 4240 40 . . . cord-006870-f5w6fw6q 4241 1 Placement placement NN cord-006870-f5w6fw6q 4241 2 of of IN cord-006870-f5w6fw6q 4241 3 an an DT cord-006870-f5w6fw6q 4241 4 EVD EVD NNP cord-006870-f5w6fw6q 4241 5 can can MD cord-006870-f5w6fw6q 4241 6 be be VB cord-006870-f5w6fw6q 4241 7 complicated complicate VBN cord-006870-f5w6fw6q 4241 8 by by IN cord-006870-f5w6fw6q 4241 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4241 10 surrounding surround VBG cord-006870-f5w6fw6q 4241 11 the the DT cord-006870-f5w6fw6q 4241 12 catheter catheter NN cord-006870-f5w6fw6q 4241 13 insertion insertion NN cord-006870-f5w6fw6q 4241 14 tract tract NN cord-006870-f5w6fw6q 4241 15 , , , cord-006870-f5w6fw6q 4241 16 which which WDT cord-006870-f5w6fw6q 4241 17 in in IN cord-006870-f5w6fw6q 4241 18 some some DT cord-006870-f5w6fw6q 4241 19 cases case NNS cord-006870-f5w6fw6q 4241 20 may may MD cord-006870-f5w6fw6q 4241 21 prove prove VB cord-006870-f5w6fw6q 4241 22 to to TO cord-006870-f5w6fw6q 4241 23 be be VB cord-006870-f5w6fw6q 4241 24 fatal fatal JJ cord-006870-f5w6fw6q 4241 25 . . . cord-006870-f5w6fw6q 4242 1 This this DT cord-006870-f5w6fw6q 4242 2 retrospective retrospective JJ cord-006870-f5w6fw6q 4242 3 study study NN cord-006870-f5w6fw6q 4242 4 was be VBD cord-006870-f5w6fw6q 4242 5 designed design VBN cord-006870-f5w6fw6q 4242 6 to to TO cord-006870-f5w6fw6q 4242 7 look look VB cord-006870-f5w6fw6q 4242 8 at at IN cord-006870-f5w6fw6q 4242 9 the the DT cord-006870-f5w6fw6q 4242 10 rate rate NN cord-006870-f5w6fw6q 4242 11 of of IN cord-006870-f5w6fw6q 4242 12 tract tract JJ cord-006870-f5w6fw6q 4242 13 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4242 14 after after IN cord-006870-f5w6fw6q 4242 15 EVD evd NN cord-006870-f5w6fw6q 4242 16 placement placement NN cord-006870-f5w6fw6q 4242 17 that that WDT cord-006870-f5w6fw6q 4242 18 were be VBD cord-006870-f5w6fw6q 4242 19 performed perform VBN cord-006870-f5w6fw6q 4242 20 at at IN cord-006870-f5w6fw6q 4242 21 our -PRON- PRP$ cord-006870-f5w6fw6q 4242 22 institution institution NN cord-006870-f5w6fw6q 4242 23 as as RB cord-006870-f5w6fw6q 4242 24 well well RB cord-006870-f5w6fw6q 4242 25 as as IN cord-006870-f5w6fw6q 4242 26 associated associate VBN cord-006870-f5w6fw6q 4242 27 outcomes outcome NNS cord-006870-f5w6fw6q 4242 28 . . . cord-006870-f5w6fw6q 4243 1 We -PRON- PRP cord-006870-f5w6fw6q 4243 2 conducted conduct VBD cord-006870-f5w6fw6q 4243 3 a a DT cord-006870-f5w6fw6q 4243 4 retrospective retrospective JJ cord-006870-f5w6fw6q 4243 5 review review NN cord-006870-f5w6fw6q 4243 6 of of IN cord-006870-f5w6fw6q 4243 7 all all DT cord-006870-f5w6fw6q 4243 8 patients patient NNS cord-006870-f5w6fw6q 4243 9 who who WP cord-006870-f5w6fw6q 4243 10 underwent undergo VBD cord-006870-f5w6fw6q 4243 11 EVD evd JJ cord-006870-f5w6fw6q 4243 12 placement placement NN cord-006870-f5w6fw6q 4243 13 during during IN cord-006870-f5w6fw6q 4243 14 a a DT cord-006870-f5w6fw6q 4243 15 3 3 CD cord-006870-f5w6fw6q 4243 16 year year NN cord-006870-f5w6fw6q 4243 17 period period NN cord-006870-f5w6fw6q 4243 18 using use VBG cord-006870-f5w6fw6q 4243 19 our -PRON- PRP$ cord-006870-f5w6fw6q 4243 20 institutional institutional JJ cord-006870-f5w6fw6q 4243 21 database database NN cord-006870-f5w6fw6q 4243 22 . . . cord-006870-f5w6fw6q 4244 1 Postinsertion postinsertion NN cord-006870-f5w6fw6q 4244 2 computerized computerized JJ cord-006870-f5w6fw6q 4244 3 tomography tomography NN cord-006870-f5w6fw6q 4244 4 ( ( -LRB- cord-006870-f5w6fw6q 4244 5 CT CT NNP cord-006870-f5w6fw6q 4244 6 ) ) -RRB- cord-006870-f5w6fw6q 4244 7 scans scan NNS cord-006870-f5w6fw6q 4244 8 of of IN cord-006870-f5w6fw6q 4244 9 the the DT cord-006870-f5w6fw6q 4244 10 head head NN cord-006870-f5w6fw6q 4244 11 were be VBD cord-006870-f5w6fw6q 4244 12 analyzed analyze VBN cord-006870-f5w6fw6q 4244 13 independently independently RB cord-006870-f5w6fw6q 4244 14 by by IN cord-006870-f5w6fw6q 4244 15 2 2 CD cord-006870-f5w6fw6q 4244 16 physicians physician NNS cord-006870-f5w6fw6q 4244 17 to to IN cord-006870-f5w6fw6q 4244 18 identifying identify VBG cord-006870-f5w6fw6q 4244 19 tract tract JJ cord-006870-f5w6fw6q 4244 20 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4244 21 . . . cord-006870-f5w6fw6q 4245 1 Data datum NNS cord-006870-f5w6fw6q 4245 2 on on IN cord-006870-f5w6fw6q 4245 3 primary primary JJ cord-006870-f5w6fw6q 4245 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 4245 5 , , , cord-006870-f5w6fw6q 4245 6 age age NN cord-006870-f5w6fw6q 4245 7 , , , cord-006870-f5w6fw6q 4245 8 sex sex NN cord-006870-f5w6fw6q 4245 9 , , , cord-006870-f5w6fw6q 4245 10 length length NN cord-006870-f5w6fw6q 4245 11 of of IN cord-006870-f5w6fw6q 4245 12 ICU ICU NNP cord-006870-f5w6fw6q 4245 13 stay stay NN cord-006870-f5w6fw6q 4245 14 and and CC cord-006870-f5w6fw6q 4245 15 mortality mortality NN cord-006870-f5w6fw6q 4245 16 were be VBD cord-006870-f5w6fw6q 4245 17 collected collect VBN cord-006870-f5w6fw6q 4245 18 and and CC cord-006870-f5w6fw6q 4245 19 analyzed analyze VBN cord-006870-f5w6fw6q 4245 20 . . . cord-006870-f5w6fw6q 4246 1 A a DT cord-006870-f5w6fw6q 4246 2 total total NN cord-006870-f5w6fw6q 4246 3 of of IN cord-006870-f5w6fw6q 4246 4 115 115 CD cord-006870-f5w6fw6q 4246 5 patients patient NNS cord-006870-f5w6fw6q 4246 6 were be VBD cord-006870-f5w6fw6q 4246 7 identified identify VBN cord-006870-f5w6fw6q 4246 8 as as IN cord-006870-f5w6fw6q 4246 9 having have VBG cord-006870-f5w6fw6q 4246 10 had have VBD cord-006870-f5w6fw6q 4246 11 an an DT cord-006870-f5w6fw6q 4246 12 EVD EVD NNP cord-006870-f5w6fw6q 4246 13 placed place VBN cord-006870-f5w6fw6q 4246 14 during during IN cord-006870-f5w6fw6q 4246 15 their -PRON- PRP$ cord-006870-f5w6fw6q 4246 16 hospital hospital NN cord-006870-f5w6fw6q 4246 17 course course NN cord-006870-f5w6fw6q 4246 18 . . . cord-006870-f5w6fw6q 4247 1 15 15 CD cord-006870-f5w6fw6q 4247 2 patients patient NNS cord-006870-f5w6fw6q 4247 3 were be VBD cord-006870-f5w6fw6q 4247 4 excluded exclude VBN cord-006870-f5w6fw6q 4247 5 as as IN cord-006870-f5w6fw6q 4247 6 there there EX cord-006870-f5w6fw6q 4247 7 were be VBD cord-006870-f5w6fw6q 4247 8 no no DT cord-006870-f5w6fw6q 4247 9 images image NNS cord-006870-f5w6fw6q 4247 10 of of IN cord-006870-f5w6fw6q 4247 11 EVDs evds NN cord-006870-f5w6fw6q 4247 12 present present JJ cord-006870-f5w6fw6q 4247 13 in in IN cord-006870-f5w6fw6q 4247 14 their -PRON- PRP$ cord-006870-f5w6fw6q 4247 15 records record NNS cord-006870-f5w6fw6q 4247 16 . . . cord-006870-f5w6fw6q 4248 1 100 100 CD cord-006870-f5w6fw6q 4248 2 patients patient NNS cord-006870-f5w6fw6q 4248 3 were be VBD cord-006870-f5w6fw6q 4248 4 analyzed analyze VBN cord-006870-f5w6fw6q 4248 5 , , , cord-006870-f5w6fw6q 4248 6 of of IN cord-006870-f5w6fw6q 4248 7 which which WDT cord-006870-f5w6fw6q 4248 8 43 43 CD cord-006870-f5w6fw6q 4248 9 % % NN cord-006870-f5w6fw6q 4248 10 were be VBD cord-006870-f5w6fw6q 4248 11 male male JJ cord-006870-f5w6fw6q 4248 12 . . . cord-006870-f5w6fw6q 4249 1 Mean mean JJ cord-006870-f5w6fw6q 4249 2 age age NN cord-006870-f5w6fw6q 4249 3 was be VBD cord-006870-f5w6fw6q 4249 4 59.4 59.4 CD cord-006870-f5w6fw6q 4249 5 years year NNS cord-006870-f5w6fw6q 4249 6 . . . cord-006870-f5w6fw6q 4250 1 50 50 CD cord-006870-f5w6fw6q 4250 2 % % NN cord-006870-f5w6fw6q 4250 3 of of IN cord-006870-f5w6fw6q 4250 4 patients patient NNS cord-006870-f5w6fw6q 4250 5 had have VBD cord-006870-f5w6fw6q 4250 6 a a DT cord-006870-f5w6fw6q 4250 7 diagnosis diagnosis NN cord-006870-f5w6fw6q 4250 8 of of IN cord-006870-f5w6fw6q 4250 9 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4250 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4250 11 , , , cord-006870-f5w6fw6q 4250 12 45 45 CD cord-006870-f5w6fw6q 4250 13 % % NN cord-006870-f5w6fw6q 4250 14 with with IN cord-006870-f5w6fw6q 4250 15 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 4250 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4250 17 and and CC cord-006870-f5w6fw6q 4250 18 16 16 CD cord-006870-f5w6fw6q 4250 19 % % NN cord-006870-f5w6fw6q 4250 20 with with IN cord-006870-f5w6fw6q 4250 21 ischemic ischemic JJ cord-006870-f5w6fw6q 4250 22 stroke stroke NN cord-006870-f5w6fw6q 4250 23 . . . cord-006870-f5w6fw6q 4251 1 Mortality mortality NN cord-006870-f5w6fw6q 4251 2 was be VBD cord-006870-f5w6fw6q 4251 3 15 15 CD cord-006870-f5w6fw6q 4251 4 % % NN cord-006870-f5w6fw6q 4251 5 among among IN cord-006870-f5w6fw6q 4251 6 all all DT cord-006870-f5w6fw6q 4251 7 EVD EVD NNP cord-006870-f5w6fw6q 4251 8 patients patient NNS cord-006870-f5w6fw6q 4251 9 . . . cord-006870-f5w6fw6q 4252 1 The the DT cord-006870-f5w6fw6q 4252 2 rate rate NN cord-006870-f5w6fw6q 4252 3 of of IN cord-006870-f5w6fw6q 4252 4 tract tract JJ cord-006870-f5w6fw6q 4252 5 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4252 6 among among IN cord-006870-f5w6fw6q 4252 7 all all DT cord-006870-f5w6fw6q 4252 8 patients patient NNS cord-006870-f5w6fw6q 4252 9 with with IN cord-006870-f5w6fw6q 4252 10 EVD EVD NNP cord-006870-f5w6fw6q 4252 11 images image NNS cord-006870-f5w6fw6q 4252 12 was be VBD cord-006870-f5w6fw6q 4252 13 21 21 CD cord-006870-f5w6fw6q 4252 14 % % NN cord-006870-f5w6fw6q 4252 15 . . . cord-006870-f5w6fw6q 4253 1 Asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 4253 2 tract tract NN cord-006870-f5w6fw6q 4253 3 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4253 4 occurred occur VBD cord-006870-f5w6fw6q 4253 5 in in IN cord-006870-f5w6fw6q 4253 6 19 19 CD cord-006870-f5w6fw6q 4253 7 patients patient NNS cord-006870-f5w6fw6q 4253 8 ( ( -LRB- cord-006870-f5w6fw6q 4253 9 95.23 95.23 CD cord-006870-f5w6fw6q 4253 10 % % NN cord-006870-f5w6fw6q 4253 11 ) ) -RRB- cord-006870-f5w6fw6q 4253 12 with with IN cord-006870-f5w6fw6q 4253 13 1 1 CD cord-006870-f5w6fw6q 4253 14 patient patient NN cord-006870-f5w6fw6q 4253 15 ( ( -LRB- cord-006870-f5w6fw6q 4253 16 4.77 4.77 CD cord-006870-f5w6fw6q 4253 17 % % NN cord-006870-f5w6fw6q 4253 18 ) ) -RRB- cord-006870-f5w6fw6q 4253 19 dying die VBG cord-006870-f5w6fw6q 4253 20 due due IN cord-006870-f5w6fw6q 4253 21 to to IN cord-006870-f5w6fw6q 4253 22 the the DT cord-006870-f5w6fw6q 4253 23 tract tract NN cord-006870-f5w6fw6q 4253 24 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4253 25 itself -PRON- PRP cord-006870-f5w6fw6q 4253 26 . . . cord-006870-f5w6fw6q 4254 1 Among among IN cord-006870-f5w6fw6q 4254 2 patients patient NNS cord-006870-f5w6fw6q 4254 3 with with IN cord-006870-f5w6fw6q 4254 4 tract tract JJ cord-006870-f5w6fw6q 4254 5 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4254 6 mortality mortality NN cord-006870-f5w6fw6q 4254 7 was be VBD cord-006870-f5w6fw6q 4254 8 14.3 14.3 CD cord-006870-f5w6fw6q 4254 9 % % NN cord-006870-f5w6fw6q 4254 10 . . . cord-006870-f5w6fw6q 4255 1 The the DT cord-006870-f5w6fw6q 4255 2 rate rate NN cord-006870-f5w6fw6q 4255 3 of of IN cord-006870-f5w6fw6q 4255 4 tract tract NN cord-006870-f5w6fw6q 4255 5 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4255 6 was be VBD cord-006870-f5w6fw6q 4255 7 noted note VBN cord-006870-f5w6fw6q 4255 8 to to TO cord-006870-f5w6fw6q 4255 9 be be VB cord-006870-f5w6fw6q 4255 10 21 21 CD cord-006870-f5w6fw6q 4255 11 % % NN cord-006870-f5w6fw6q 4255 12 with with IN cord-006870-f5w6fw6q 4255 13 the the DT cord-006870-f5w6fw6q 4255 14 majority majority NN cord-006870-f5w6fw6q 4255 15 being be VBG cord-006870-f5w6fw6q 4255 16 asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 4255 17 . . . cord-006870-f5w6fw6q 4256 1 There there EX cord-006870-f5w6fw6q 4256 2 was be VBD cord-006870-f5w6fw6q 4256 3 no no DT cord-006870-f5w6fw6q 4256 4 difference difference NN cord-006870-f5w6fw6q 4256 5 in in IN cord-006870-f5w6fw6q 4256 6 mortality mortality NN cord-006870-f5w6fw6q 4256 7 among among IN cord-006870-f5w6fw6q 4256 8 patients patient NNS cord-006870-f5w6fw6q 4256 9 with with IN cord-006870-f5w6fw6q 4256 10 EVDs evd NNS cord-006870-f5w6fw6q 4256 11 who who WP cord-006870-f5w6fw6q 4256 12 developed develop VBD cord-006870-f5w6fw6q 4256 13 tract tract JJ cord-006870-f5w6fw6q 4256 14 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4256 15 compared compare VBN cord-006870-f5w6fw6q 4256 16 to to IN cord-006870-f5w6fw6q 4256 17 patients patient NNS cord-006870-f5w6fw6q 4256 18 with with IN cord-006870-f5w6fw6q 4256 19 no no DT cord-006870-f5w6fw6q 4256 20 tract tract NN cord-006870-f5w6fw6q 4256 21 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 4256 22 . . . cord-006870-f5w6fw6q 4257 1 Verapamil Verapamil NNP cord-006870-f5w6fw6q 4257 2 is be VBZ cord-006870-f5w6fw6q 4257 3 a a DT cord-006870-f5w6fw6q 4257 4 phenylalkylamine phenylalkylamine JJ cord-006870-f5w6fw6q 4257 5 calcium calcium NN cord-006870-f5w6fw6q 4257 6 channel channel NN cord-006870-f5w6fw6q 4257 7 blocker blocker NN cord-006870-f5w6fw6q 4257 8 that that WDT cord-006870-f5w6fw6q 4257 9 blocks block VBZ cord-006870-f5w6fw6q 4257 10 the the DT cord-006870-f5w6fw6q 4257 11 calcium calcium NN cord-006870-f5w6fw6q 4257 12 ion ion NN cord-006870-f5w6fw6q 4257 13 influx influx NN cord-006870-f5w6fw6q 4257 14 through through IN cord-006870-f5w6fw6q 4257 15 slow slow JJ cord-006870-f5w6fw6q 4257 16 channels channel NNS cord-006870-f5w6fw6q 4257 17 into into IN cord-006870-f5w6fw6q 4257 18 conductile conductile NN cord-006870-f5w6fw6q 4257 19 and and CC cord-006870-f5w6fw6q 4257 20 contractile contractile JJ cord-006870-f5w6fw6q 4257 21 myocardial myocardial JJ cord-006870-f5w6fw6q 4257 22 cells cell NNS cord-006870-f5w6fw6q 4257 23 and and CC cord-006870-f5w6fw6q 4257 24 vascular vascular JJ cord-006870-f5w6fw6q 4257 25 smooth smooth JJ cord-006870-f5w6fw6q 4257 26 muscle muscle NN cord-006870-f5w6fw6q 4257 27 cells cell NNS cord-006870-f5w6fw6q 4257 28 resulting result VBG cord-006870-f5w6fw6q 4257 29 in in IN cord-006870-f5w6fw6q 4257 30 vascular vascular JJ cord-006870-f5w6fw6q 4257 31 relaxation relaxation NN cord-006870-f5w6fw6q 4257 32 and and CC cord-006870-f5w6fw6q 4257 33 vasodilatation vasodilatation NN cord-006870-f5w6fw6q 4257 34 . . . cord-006870-f5w6fw6q 4258 1 Symptomatic symptomatic JJ cord-006870-f5w6fw6q 4258 2 hypotension hypotension NN cord-006870-f5w6fw6q 4258 3 and/or and/or CC cord-006870-f5w6fw6q 4258 4 extreme extreme JJ cord-006870-f5w6fw6q 4258 5 bradycardia bradycardia NN cord-006870-f5w6fw6q 4258 6 / / SYM cord-006870-f5w6fw6q 4258 7 asystole asystole NN cord-006870-f5w6fw6q 4258 8 are be VBP cord-006870-f5w6fw6q 4258 9 often often RB cord-006870-f5w6fw6q 4258 10 seen see VBN cord-006870-f5w6fw6q 4258 11 with with IN cord-006870-f5w6fw6q 4258 12 intravenous intravenous JJ cord-006870-f5w6fw6q 4258 13 verapamil verapamil NN cord-006870-f5w6fw6q 4258 14 administration administration NN cord-006870-f5w6fw6q 4258 15 requiring require VBG cord-006870-f5w6fw6q 4258 16 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 4258 17 treatment treatment NN cord-006870-f5w6fw6q 4258 18 . . . cord-006870-f5w6fw6q 4259 1 In in IN cord-006870-f5w6fw6q 4259 2 Neuroendovascular Neuroendovascular NNP cord-006870-f5w6fw6q 4259 3 field field NN cord-006870-f5w6fw6q 4259 4 verapamil verapamil NN cord-006870-f5w6fw6q 4259 5 is be VBZ cord-006870-f5w6fw6q 4259 6 mainly mainly RB cord-006870-f5w6fw6q 4259 7 being be VBG cord-006870-f5w6fw6q 4259 8 used use VBN cord-006870-f5w6fw6q 4259 9 as as IN cord-006870-f5w6fw6q 4259 10 a a DT cord-006870-f5w6fw6q 4259 11 vasodilator vasodilator NN cord-006870-f5w6fw6q 4259 12 agent agent NN cord-006870-f5w6fw6q 4259 13 . . . cord-006870-f5w6fw6q 4260 1 Current current JJ cord-006870-f5w6fw6q 4260 2 lack lack NN cord-006870-f5w6fw6q 4260 3 of of IN cord-006870-f5w6fw6q 4260 4 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 4260 5 / / SYM cord-006870-f5w6fw6q 4260 6 pharmacodynamics pharmacodynamic NNS cord-006870-f5w6fw6q 4260 7 data datum NNS cord-006870-f5w6fw6q 4260 8 of of IN cord-006870-f5w6fw6q 4260 9 intra intra JJ cord-006870-f5w6fw6q 4260 10 - - JJ cord-006870-f5w6fw6q 4260 11 arterial arterial JJ cord-006870-f5w6fw6q 4260 12 verapamil verapamil NN cord-006870-f5w6fw6q 4260 13 often often RB cord-006870-f5w6fw6q 4260 14 makes make VBZ cord-006870-f5w6fw6q 4260 15 very very RB cord-006870-f5w6fw6q 4260 16 challenging challenging JJ cord-006870-f5w6fw6q 4260 17 to to IN cord-006870-f5w6fw6q 4260 18 neurointerventionalists neurointerventionalist NNS cord-006870-f5w6fw6q 4260 19 during during IN cord-006870-f5w6fw6q 4260 20 endovascular endovascular JJ cord-006870-f5w6fw6q 4260 21 procedures procedure NNS cord-006870-f5w6fw6q 4260 22 . . . cord-006870-f5w6fw6q 4261 1 The the DT cord-006870-f5w6fw6q 4261 2 purpose purpose NN cord-006870-f5w6fw6q 4261 3 of of IN cord-006870-f5w6fw6q 4261 4 this this DT cord-006870-f5w6fw6q 4261 5 study study NN cord-006870-f5w6fw6q 4261 6 is be VBZ cord-006870-f5w6fw6q 4261 7 to to TO cord-006870-f5w6fw6q 4261 8 observe observe VB cord-006870-f5w6fw6q 4261 9 acute acute JJ cord-006870-f5w6fw6q 4261 10 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 4261 11 effects effect NNS cord-006870-f5w6fw6q 4261 12 of of IN cord-006870-f5w6fw6q 4261 13 intra intra JJ cord-006870-f5w6fw6q 4261 14 - - JJ cord-006870-f5w6fw6q 4261 15 arterial arterial JJ cord-006870-f5w6fw6q 4261 16 verapamil verapamil NN cord-006870-f5w6fw6q 4261 17 administration administration NN cord-006870-f5w6fw6q 4261 18 as as RB cord-006870-f5w6fw6q 4261 19 well well RB cord-006870-f5w6fw6q 4261 20 as as IN cord-006870-f5w6fw6q 4261 21 the the DT cord-006870-f5w6fw6q 4261 22 safety safety NN cord-006870-f5w6fw6q 4261 23 of of IN cord-006870-f5w6fw6q 4261 24 higher high JJR cord-006870-f5w6fw6q 4261 25 dose dose NN cord-006870-f5w6fw6q 4261 26 of of IN cord-006870-f5w6fw6q 4261 27 the the DT cord-006870-f5w6fw6q 4261 28 medication medication NN cord-006870-f5w6fw6q 4261 29 during during IN cord-006870-f5w6fw6q 4261 30 endovascular endovascular JJ cord-006870-f5w6fw6q 4261 31 treatment treatment NN cord-006870-f5w6fw6q 4261 32 . . . cord-006870-f5w6fw6q 4262 1 Ten ten CD cord-006870-f5w6fw6q 4262 2 patients patient NNS cord-006870-f5w6fw6q 4262 3 who who WP cord-006870-f5w6fw6q 4262 4 underwent undergo VBD cord-006870-f5w6fw6q 4262 5 endovascular endovascular JJ cord-006870-f5w6fw6q 4262 6 treatment treatment NN cord-006870-f5w6fw6q 4262 7 for for IN cord-006870-f5w6fw6q 4262 8 acute acute JJ cord-006870-f5w6fw6q 4262 9 ischemic ischemic JJ cord-006870-f5w6fw6q 4262 10 stroke stroke NN cord-006870-f5w6fw6q 4262 11 were be VBD cord-006870-f5w6fw6q 4262 12 evaluated evaluate VBN cord-006870-f5w6fw6q 4262 13 pre pre JJ cord-006870-f5w6fw6q 4262 14 and and CC cord-006870-f5w6fw6q 4262 15 post post JJ cord-006870-f5w6fw6q 4262 16 procedure procedure NN cord-006870-f5w6fw6q 4262 17 with with IN cord-006870-f5w6fw6q 4262 18 vital vital JJ cord-006870-f5w6fw6q 4262 19 signs sign NNS cord-006870-f5w6fw6q 4262 20 . . . cord-006870-f5w6fw6q 4263 1 The the DT cord-006870-f5w6fw6q 4263 2 dosage dosage NN cord-006870-f5w6fw6q 4263 3 of of IN cord-006870-f5w6fw6q 4263 4 intra intra JJ cord-006870-f5w6fw6q 4263 5 - - JJ cord-006870-f5w6fw6q 4263 6 arterial arterial JJ cord-006870-f5w6fw6q 4263 7 verapamil verapamil NN cord-006870-f5w6fw6q 4263 8 was be VBD cord-006870-f5w6fw6q 4263 9 documented document VBN cord-006870-f5w6fw6q 4263 10 and and CC cord-006870-f5w6fw6q 4263 11 tabulated tabulate VBN cord-006870-f5w6fw6q 4263 12 along along RP cord-006870-f5w6fw6q 4263 13 with with IN cord-006870-f5w6fw6q 4263 14 the the DT cord-006870-f5w6fw6q 4263 15 pre pre JJ cord-006870-f5w6fw6q 4263 16 and and CC cord-006870-f5w6fw6q 4263 17 post post JJ cord-006870-f5w6fw6q 4263 18 heart heart NN cord-006870-f5w6fw6q 4263 19 rate rate NN cord-006870-f5w6fw6q 4263 20 and and CC cord-006870-f5w6fw6q 4263 21 systolic systolic JJ cord-006870-f5w6fw6q 4263 22 blood blood NN cord-006870-f5w6fw6q 4263 23 pressure pressure NN cord-006870-f5w6fw6q 4263 24 . . . cord-006870-f5w6fw6q 4264 1 The the DT cord-006870-f5w6fw6q 4264 2 dose dose NN cord-006870-f5w6fw6q 4264 3 of of IN cord-006870-f5w6fw6q 4264 4 intra intra JJ cord-006870-f5w6fw6q 4264 5 - - JJ cord-006870-f5w6fw6q 4264 6 arterial arterial JJ cord-006870-f5w6fw6q 4264 7 verapamil verapamil NN cord-006870-f5w6fw6q 4264 8 varied vary VBN cord-006870-f5w6fw6q 4264 9 from from IN cord-006870-f5w6fw6q 4264 10 1 1 CD cord-006870-f5w6fw6q 4264 11 to to IN cord-006870-f5w6fw6q 4264 12 5 5 CD cord-006870-f5w6fw6q 4264 13 mg mg NNS cord-006870-f5w6fw6q 4264 14 in in IN cord-006870-f5w6fw6q 4264 15 each each DT cord-006870-f5w6fw6q 4264 16 Internal Internal NNP cord-006870-f5w6fw6q 4264 17 Carotid Carotid NNP cord-006870-f5w6fw6q 4264 18 or or CC cord-006870-f5w6fw6q 4264 19 Vertebral vertebral JJ cord-006870-f5w6fw6q 4264 20 artery artery NN cord-006870-f5w6fw6q 4264 21 , , , cord-006870-f5w6fw6q 4264 22 total total JJ cord-006870-f5w6fw6q 4264 23 dose dose NN cord-006870-f5w6fw6q 4264 24 per per IN cord-006870-f5w6fw6q 4264 25 patient patient NN cord-006870-f5w6fw6q 4264 26 per per IN cord-006870-f5w6fw6q 4264 27 procedure procedure NN cord-006870-f5w6fw6q 4264 28 varied varied JJ cord-006870-f5w6fw6q 4264 29 from from IN cord-006870-f5w6fw6q 4264 30 2.5 2.5 CD cord-006870-f5w6fw6q 4264 31 to to IN cord-006870-f5w6fw6q 4264 32 10 10 CD cord-006870-f5w6fw6q 4264 33 . . . cord-006870-f5w6fw6q 4265 1 The the DT cord-006870-f5w6fw6q 4265 2 average average JJ cord-006870-f5w6fw6q 4265 3 dose dose NN cord-006870-f5w6fw6q 4265 4 of of IN cord-006870-f5w6fw6q 4265 5 intra intra JJ cord-006870-f5w6fw6q 4265 6 - - JJ cord-006870-f5w6fw6q 4265 7 arterial arterial JJ cord-006870-f5w6fw6q 4265 8 verapamil verapamil NN cord-006870-f5w6fw6q 4265 9 administered administer VBN cord-006870-f5w6fw6q 4265 10 was be VBD cord-006870-f5w6fw6q 4265 11 4.95 4.95 CD cord-006870-f5w6fw6q 4265 12 ± ± NNP cord-006870-f5w6fw6q 4265 13 2.0 2.0 CD cord-006870-f5w6fw6q 4265 14 mg mg NN cord-006870-f5w6fw6q 4265 15 or or CC cord-006870-f5w6fw6q 4265 16 59.7 59.7 CD cord-006870-f5w6fw6q 4265 17 ± ± CD cord-006870-f5w6fw6q 4265 18 30.8 30.8 CD cord-006870-f5w6fw6q 4265 19 mcg mcg NNP cord-006870-f5w6fw6q 4265 20 / / SYM cord-006870-f5w6fw6q 4265 21 kg kg NNP cord-006870-f5w6fw6q 4265 22 that that WDT cord-006870-f5w6fw6q 4265 23 were be VBD cord-006870-f5w6fw6q 4265 24 infused infuse VBN cord-006870-f5w6fw6q 4265 25 over over IN cord-006870-f5w6fw6q 4265 26 5 5 CD cord-006870-f5w6fw6q 4265 27 to to TO cord-006870-f5w6fw6q 4265 28 10 10 CD cord-006870-f5w6fw6q 4265 29 minutes minute NNS cord-006870-f5w6fw6q 4265 30 . . . cord-006870-f5w6fw6q 4266 1 At at IN cord-006870-f5w6fw6q 4266 2 the the DT cord-006870-f5w6fw6q 4266 3 baseline baseline NN cord-006870-f5w6fw6q 4266 4 before before IN cord-006870-f5w6fw6q 4266 5 administration administration NN cord-006870-f5w6fw6q 4266 6 of of IN cord-006870-f5w6fw6q 4266 7 intra intra JJ cord-006870-f5w6fw6q 4266 8 - - JJ cord-006870-f5w6fw6q 4266 9 arterial arterial JJ cord-006870-f5w6fw6q 4266 10 verapamil verapamil NN cord-006870-f5w6fw6q 4266 11 , , , cord-006870-f5w6fw6q 4266 12 the the DT cord-006870-f5w6fw6q 4266 13 mean mean JJ cord-006870-f5w6fw6q 4266 14 systolic systolic JJ cord-006870-f5w6fw6q 4266 15 blood blood NN cord-006870-f5w6fw6q 4266 16 pressure pressure NN cord-006870-f5w6fw6q 4266 17 ( ( -LRB- cord-006870-f5w6fw6q 4266 18 SBP SBP NNP cord-006870-f5w6fw6q 4266 19 ) ) -RRB- cord-006870-f5w6fw6q 4266 20 was be VBD cord-006870-f5w6fw6q 4266 21 157.8 157.8 CD cord-006870-f5w6fw6q 4266 22 ± ± XX cord-006870-f5w6fw6q 4267 1 24.4 24.4 CD cord-006870-f5w6fw6q 4267 2 mm mm NNP cord-006870-f5w6fw6q 4267 3 Hg Hg NNP cord-006870-f5w6fw6q 4267 4 and and CC cord-006870-f5w6fw6q 4267 5 the the DT cord-006870-f5w6fw6q 4267 6 mean mean JJ cord-006870-f5w6fw6q 4267 7 heart heart NN cord-006870-f5w6fw6q 4267 8 rate rate NN cord-006870-f5w6fw6q 4267 9 ( ( -LRB- cord-006870-f5w6fw6q 4267 10 HR HR NNP cord-006870-f5w6fw6q 4267 11 ) ) -RRB- cord-006870-f5w6fw6q 4267 12 was be VBD cord-006870-f5w6fw6q 4267 13 71.6 71.6 CD cord-006870-f5w6fw6q 4267 14 ± ± CD cord-006870-f5w6fw6q 4267 15 16.2 16.2 CD cord-006870-f5w6fw6q 4267 16 bpm bpm NNP cord-006870-f5w6fw6q 4267 17 . . . cord-006870-f5w6fw6q 4268 1 After after IN cord-006870-f5w6fw6q 4268 2 administration administration NN cord-006870-f5w6fw6q 4268 3 of of IN cord-006870-f5w6fw6q 4268 4 intraarterial intraarterial NNP cord-006870-f5w6fw6q 4268 5 verapamil verapamil NN cord-006870-f5w6fw6q 4268 6 , , , cord-006870-f5w6fw6q 4268 7 SBP SBP NNP cord-006870-f5w6fw6q 4268 8 decreased decrease VBD cord-006870-f5w6fw6q 4268 9 by by IN cord-006870-f5w6fw6q 4268 10 mean mean NN cord-006870-f5w6fw6q 4268 11 of of IN cord-006870-f5w6fw6q 4268 12 16.7 16.7 CD cord-006870-f5w6fw6q 4268 13 ± ± NNP cord-006870-f5w6fw6q 4268 14 0.8 0.8 CD cord-006870-f5w6fw6q 4268 15 mm mm NN cord-006870-f5w6fw6q 4269 1 Hg Hg NNP cord-006870-f5w6fw6q 4270 1 but but CC cord-006870-f5w6fw6q 4270 2 we -PRON- PRP cord-006870-f5w6fw6q 4270 3 observed observe VBD cord-006870-f5w6fw6q 4270 4 no no DT cord-006870-f5w6fw6q 4270 5 symptomatic symptomatic JJ cord-006870-f5w6fw6q 4270 6 hypotension hypotension NN cord-006870-f5w6fw6q 4270 7 requiring require VBG cord-006870-f5w6fw6q 4270 8 any any DT cord-006870-f5w6fw6q 4270 9 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 4270 10 treatment treatment NN cord-006870-f5w6fw6q 4270 11 . . . cord-006870-f5w6fw6q 4271 1 HR HR NNP cord-006870-f5w6fw6q 4271 2 changed change VBN cord-006870-f5w6fw6q 4271 3 only only RB cord-006870-f5w6fw6q 4271 4 by by IN cord-006870-f5w6fw6q 4271 5 mean mean NN cord-006870-f5w6fw6q 4271 6 of of IN cord-006870-f5w6fw6q 4271 7 0.1 0.1 CD cord-006870-f5w6fw6q 4271 8 ± ± CD cord-006870-f5w6fw6q 4271 9 5.4 5.4 CD cord-006870-f5w6fw6q 4271 10 bpm bpm NNP cord-006870-f5w6fw6q 4271 11 post post JJ cord-006870-f5w6fw6q 4271 12 intra intra JJ cord-006870-f5w6fw6q 4271 13 - - JJ cord-006870-f5w6fw6q 4271 14 arterial arterial JJ cord-006870-f5w6fw6q 4271 15 verapamil verapamil NN cord-006870-f5w6fw6q 4271 16 . . . cord-006870-f5w6fw6q 4272 1 We -PRON- PRP cord-006870-f5w6fw6q 4272 2 observed observe VBD cord-006870-f5w6fw6q 4272 3 no no DT cord-006870-f5w6fw6q 4272 4 acute acute JJ cord-006870-f5w6fw6q 4272 5 significant significant JJ cord-006870-f5w6fw6q 4272 6 changes change NNS cord-006870-f5w6fw6q 4272 7 in in IN cord-006870-f5w6fw6q 4272 8 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 4272 9 parameters parameter NNS cord-006870-f5w6fw6q 4272 10 with with IN cord-006870-f5w6fw6q 4272 11 administration administration NN cord-006870-f5w6fw6q 4272 12 of of IN cord-006870-f5w6fw6q 4272 13 verapamil verapamil NN cord-006870-f5w6fw6q 4272 14 in in IN cord-006870-f5w6fw6q 4272 15 Carotid Carotid NNP cord-006870-f5w6fw6q 4272 16 or or CC cord-006870-f5w6fw6q 4272 17 Vertebral vertebral JJ cord-006870-f5w6fw6q 4272 18 arteries artery NNS cord-006870-f5w6fw6q 4272 19 . . . cord-006870-f5w6fw6q 4273 1 This this DT cord-006870-f5w6fw6q 4273 2 may may MD cord-006870-f5w6fw6q 4273 3 represent represent VB cord-006870-f5w6fw6q 4273 4 its -PRON- PRP$ cord-006870-f5w6fw6q 4273 5 safe safe JJ cord-006870-f5w6fw6q 4273 6 use use NN cord-006870-f5w6fw6q 4273 7 during during IN cord-006870-f5w6fw6q 4273 8 Neuro Neuro NNP cord-006870-f5w6fw6q 4273 9 - - HYPH cord-006870-f5w6fw6q 4273 10 endovascular endovascular JJ cord-006870-f5w6fw6q 4273 11 therapy therapy NN cord-006870-f5w6fw6q 4273 12 . . . cord-006870-f5w6fw6q 4274 1 Growing grow VBG cord-006870-f5w6fw6q 4274 2 evidence evidence NN cord-006870-f5w6fw6q 4274 3 suggests suggest VBZ cord-006870-f5w6fw6q 4274 4 inflammation inflammation NN cord-006870-f5w6fw6q 4274 5 is be VBZ cord-006870-f5w6fw6q 4274 6 critical critical JJ cord-006870-f5w6fw6q 4274 7 in in IN cord-006870-f5w6fw6q 4274 8 epileptogenesis epileptogenesis NN cord-006870-f5w6fw6q 4274 9 . . . cord-006870-f5w6fw6q 4275 1 Endogenous endogenous JJ cord-006870-f5w6fw6q 4275 2 brain brain NN cord-006870-f5w6fw6q 4276 1 apolipoprotein apolipoprotein NNP cord-006870-f5w6fw6q 4276 2 E E NNP cord-006870-f5w6fw6q 4276 3 protein protein NN cord-006870-f5w6fw6q 4276 4 ( ( -LRB- cord-006870-f5w6fw6q 4276 5 apoE apoE NNS cord-006870-f5w6fw6q 4276 6 ) ) -RRB- cord-006870-f5w6fw6q 4276 7 modulates modulate VBZ cord-006870-f5w6fw6q 4276 8 neuroinflammatory neuroinflammatory JJ cord-006870-f5w6fw6q 4276 9 responses response NNS cord-006870-f5w6fw6q 4276 10 to to TO cord-006870-f5w6fw6q 4276 11 injury injury VB cord-006870-f5w6fw6q 4276 12 through through IN cord-006870-f5w6fw6q 4276 13 downregulation downregulation NN cord-006870-f5w6fw6q 4276 14 of of IN cord-006870-f5w6fw6q 4276 15 glial glial JJ cord-006870-f5w6fw6q 4276 16 activation activation NN cord-006870-f5w6fw6q 4276 17 and and CC cord-006870-f5w6fw6q 4276 18 secondary secondary JJ cord-006870-f5w6fw6q 4276 19 neuronal neuronal JJ cord-006870-f5w6fw6q 4276 20 injury injury NN cord-006870-f5w6fw6q 4276 21 . . . cord-006870-f5w6fw6q 4277 1 We -PRON- PRP cord-006870-f5w6fw6q 4277 2 created create VBD cord-006870-f5w6fw6q 4277 3 a a DT cord-006870-f5w6fw6q 4277 4 5 5 CD cord-006870-f5w6fw6q 4277 5 amino amino NN cord-006870-f5w6fw6q 4277 6 acid acid NN cord-006870-f5w6fw6q 4277 7 peptide peptide NN cord-006870-f5w6fw6q 4277 8 ( ( -LRB- cord-006870-f5w6fw6q 4277 9 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4277 10 ) ) -RRB- cord-006870-f5w6fw6q 4278 1 mimicking mimic VBG cord-006870-f5w6fw6q 4278 2 the the DT cord-006870-f5w6fw6q 4278 3 binding binding JJ cord-006870-f5w6fw6q 4278 4 face face NN cord-006870-f5w6fw6q 4278 5 of of IN cord-006870-f5w6fw6q 4278 6 apoE. apoE. NNP cord-006870-f5w6fw6q 4278 7 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4278 8 downregulates downregulate VBZ cord-006870-f5w6fw6q 4278 9 the the DT cord-006870-f5w6fw6q 4278 10 inflammatory inflammatory JJ cord-006870-f5w6fw6q 4278 11 response response NN cord-006870-f5w6fw6q 4278 12 in in IN cord-006870-f5w6fw6q 4278 13 vitro vitro FW cord-006870-f5w6fw6q 4278 14 and and CC cord-006870-f5w6fw6q 4278 15 in in IN cord-006870-f5w6fw6q 4278 16 vivo vivo NNP cord-006870-f5w6fw6q 4278 17 and and CC cord-006870-f5w6fw6q 4278 18 improved improve VBN cord-006870-f5w6fw6q 4278 19 histologic histologic JJ cord-006870-f5w6fw6q 4278 20 and and CC cord-006870-f5w6fw6q 4278 21 clinical clinical JJ cord-006870-f5w6fw6q 4278 22 outcomes outcome NNS cord-006870-f5w6fw6q 4278 23 across across IN cord-006870-f5w6fw6q 4278 24 several several JJ cord-006870-f5w6fw6q 4278 25 injury injury NN cord-006870-f5w6fw6q 4278 26 models model NNS cord-006870-f5w6fw6q 4278 27 in in IN cord-006870-f5w6fw6q 4278 28 mice mouse NNS cord-006870-f5w6fw6q 4278 29 . . . cord-006870-f5w6fw6q 4279 1 We -PRON- PRP cord-006870-f5w6fw6q 4279 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 4279 3 that that IN cord-006870-f5w6fw6q 4279 4 downregulation downregulation NN cord-006870-f5w6fw6q 4279 5 of of IN cord-006870-f5w6fw6q 4279 6 inflammation inflammation NN cord-006870-f5w6fw6q 4279 7 by by IN cord-006870-f5w6fw6q 4279 8 administration administration NN cord-006870-f5w6fw6q 4279 9 of of IN cord-006870-f5w6fw6q 4279 10 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4279 11 will will MD cord-006870-f5w6fw6q 4279 12 reduce reduce VB cord-006870-f5w6fw6q 4279 13 the the DT cord-006870-f5w6fw6q 4279 14 development development NN cord-006870-f5w6fw6q 4279 15 of of IN cord-006870-f5w6fw6q 4279 16 epilepsy epilepsy NN cord-006870-f5w6fw6q 4279 17 after after IN cord-006870-f5w6fw6q 4279 18 pilocarpine pilocarpine NNP cord-006870-f5w6fw6q 4279 19 induced induce VBN cord-006870-f5w6fw6q 4279 20 status status NN cord-006870-f5w6fw6q 4279 21 epilepticus epilepticus NN cord-006870-f5w6fw6q 4279 22 in in IN cord-006870-f5w6fw6q 4279 23 mice mouse NNS cord-006870-f5w6fw6q 4279 24 . . . cord-006870-f5w6fw6q 4280 1 C57Bl/6 C57Bl/6 JJR cord-006870-f5w6fw6q 4280 2 mice mouse NNS cord-006870-f5w6fw6q 4280 3 were be VBD cord-006870-f5w6fw6q 4280 4 intraperitoneally intraperitoneally RB cord-006870-f5w6fw6q 4280 5 injected inject VBN cord-006870-f5w6fw6q 4280 6 with with IN cord-006870-f5w6fw6q 4280 7 pilocarpine pilocarpine NN cord-006870-f5w6fw6q 4280 8 to to TO cord-006870-f5w6fw6q 4280 9 induce induce VB cord-006870-f5w6fw6q 4280 10 status status NN cord-006870-f5w6fw6q 4280 11 epilepticus epilepticus NN cord-006870-f5w6fw6q 4280 12 . . . cord-006870-f5w6fw6q 4281 1 Following follow VBG cord-006870-f5w6fw6q 4281 2 induction induction NN cord-006870-f5w6fw6q 4281 3 of of IN cord-006870-f5w6fw6q 4281 4 status status NN cord-006870-f5w6fw6q 4281 5 , , , cord-006870-f5w6fw6q 4281 6 animals animal NNS cord-006870-f5w6fw6q 4281 7 were be VBD cord-006870-f5w6fw6q 4281 8 randomized randomize VBN cord-006870-f5w6fw6q 4281 9 to to TO cord-006870-f5w6fw6q 4281 10 receive receive VB cord-006870-f5w6fw6q 4281 11 two two CD cord-006870-f5w6fw6q 4281 12 doses dose NNS cord-006870-f5w6fw6q 4281 13 of of IN cord-006870-f5w6fw6q 4281 14 CN-105 cn-105 NN cord-006870-f5w6fw6q 4281 15 or or CC cord-006870-f5w6fw6q 4281 16 vehicle vehicle NN cord-006870-f5w6fw6q 4281 17 at at IN cord-006870-f5w6fw6q 4281 18 45 45 CD cord-006870-f5w6fw6q 4281 19 minutes minute NNS cord-006870-f5w6fw6q 4281 20 and and CC cord-006870-f5w6fw6q 4281 21 6 6 CD cord-006870-f5w6fw6q 4281 22 hours hour NNS cord-006870-f5w6fw6q 4281 23 . . . cord-006870-f5w6fw6q 4282 1 Status status NN cord-006870-f5w6fw6q 4282 2 was be VBD cord-006870-f5w6fw6q 4282 3 terminated terminate VBN cord-006870-f5w6fw6q 4282 4 by by IN cord-006870-f5w6fw6q 4282 5 injection injection NN cord-006870-f5w6fw6q 4282 6 of of IN cord-006870-f5w6fw6q 4282 7 benzodiazepine benzodiazepine NN cord-006870-f5w6fw6q 4282 8 at at IN cord-006870-f5w6fw6q 4282 9 55 55 CD cord-006870-f5w6fw6q 4282 10 minutes minute NNS cord-006870-f5w6fw6q 4282 11 . . . cord-006870-f5w6fw6q 4283 1 Epidural Epidural NNP cord-006870-f5w6fw6q 4283 2 EEG EEG NNP cord-006870-f5w6fw6q 4283 3 leads lead NNS cord-006870-f5w6fw6q 4283 4 were be VBD cord-006870-f5w6fw6q 4283 5 surgically surgically RB cord-006870-f5w6fw6q 4283 6 placed place VBN cord-006870-f5w6fw6q 4283 7 at at IN cord-006870-f5w6fw6q 4283 8 3 3 CD cord-006870-f5w6fw6q 4283 9 weeks week NNS cord-006870-f5w6fw6q 4283 10 and and CC cord-006870-f5w6fw6q 4283 11 continuous continuous JJ cord-006870-f5w6fw6q 4283 12 video video NN cord-006870-f5w6fw6q 4283 13 - - HYPH cord-006870-f5w6fw6q 4283 14 EEG EEG NNP cord-006870-f5w6fw6q 4283 15 ( ( -LRB- cord-006870-f5w6fw6q 4283 16 cvEEG cveeg JJ cord-006870-f5w6fw6q 4283 17 ) ) -RRB- cord-006870-f5w6fw6q 4284 1 monitoring monitoring NN cord-006870-f5w6fw6q 4284 2 was be VBD cord-006870-f5w6fw6q 4284 3 performed perform VBN cord-006870-f5w6fw6q 4284 4 for for IN cord-006870-f5w6fw6q 4284 5 several several JJ cord-006870-f5w6fw6q 4284 6 days day NNS cord-006870-f5w6fw6q 4284 7 in in IN cord-006870-f5w6fw6q 4284 8 a a DT cord-006870-f5w6fw6q 4284 9 row row NN cord-006870-f5w6fw6q 4284 10 at at IN cord-006870-f5w6fw6q 4284 11 4 4 CD cord-006870-f5w6fw6q 4284 12 - - SYM cord-006870-f5w6fw6q 4284 13 6 6 CD cord-006870-f5w6fw6q 4284 14 weeks week NNS cord-006870-f5w6fw6q 4284 15 post post NN cord-006870-f5w6fw6q 4284 16 status status NN cord-006870-f5w6fw6q 4284 17 to to TO cord-006870-f5w6fw6q 4284 18 determine determine VB cord-006870-f5w6fw6q 4284 19 spontaneous spontaneous JJ cord-006870-f5w6fw6q 4284 20 seizure seizure NN cord-006870-f5w6fw6q 4284 21 development development NN cord-006870-f5w6fw6q 4284 22 and and CC cord-006870-f5w6fw6q 4284 23 frequency frequency NN cord-006870-f5w6fw6q 4284 24 . . . cord-006870-f5w6fw6q 4285 1 At at IN cord-006870-f5w6fw6q 4285 2 4 4 CD cord-006870-f5w6fw6q 4285 3 - - SYM cord-006870-f5w6fw6q 4285 4 6 6 CD cord-006870-f5w6fw6q 4285 5 weeks week NNS cord-006870-f5w6fw6q 4285 6 following follow VBG cord-006870-f5w6fw6q 4285 7 induction induction NN cord-006870-f5w6fw6q 4285 8 of of IN cord-006870-f5w6fw6q 4285 9 status status NN cord-006870-f5w6fw6q 4285 10 epilepticus epilepticus NN cord-006870-f5w6fw6q 4285 11 , , , cord-006870-f5w6fw6q 4285 12 administration administration NN cord-006870-f5w6fw6q 4285 13 of of IN cord-006870-f5w6fw6q 4286 1 0.2 0.2 CD cord-006870-f5w6fw6q 4286 2 or or CC cord-006870-f5w6fw6q 4286 3 0.5mg 0.5mg CD cord-006870-f5w6fw6q 4286 4 / / SYM cord-006870-f5w6fw6q 4286 5 kg kg NN cord-006870-f5w6fw6q 4286 6 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4286 7 reduced reduce VBD cord-006870-f5w6fw6q 4286 8 the the DT cord-006870-f5w6fw6q 4286 9 development development NN cord-006870-f5w6fw6q 4286 10 of of IN cord-006870-f5w6fw6q 4286 11 epilepsy epilepsy NN cord-006870-f5w6fw6q 4286 12 by by IN cord-006870-f5w6fw6q 4286 13 approximately approximately RB cord-006870-f5w6fw6q 4286 14 50 50 CD cord-006870-f5w6fw6q 4286 15 % % NN cord-006870-f5w6fw6q 4286 16 compared compare VBN cord-006870-f5w6fw6q 4286 17 to to IN cord-006870-f5w6fw6q 4286 18 vehicle vehicle NN cord-006870-f5w6fw6q 4286 19 treated treat VBN cord-006870-f5w6fw6q 4286 20 animals animal NNS cord-006870-f5w6fw6q 4286 21 . . . cord-006870-f5w6fw6q 4287 1 Further further RB cord-006870-f5w6fw6q 4287 2 , , , cord-006870-f5w6fw6q 4287 3 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4287 4 treated treat VBD cord-006870-f5w6fw6q 4287 5 animals animal NNS cord-006870-f5w6fw6q 4287 6 that that WDT cord-006870-f5w6fw6q 4287 7 did do VBD cord-006870-f5w6fw6q 4287 8 develop develop VB cord-006870-f5w6fw6q 4287 9 seizures seizure NNS cord-006870-f5w6fw6q 4287 10 had have VBD cord-006870-f5w6fw6q 4287 11 significantly significantly RB cord-006870-f5w6fw6q 4287 12 fewer few JJR cord-006870-f5w6fw6q 4287 13 seizures seizure NNS cord-006870-f5w6fw6q 4287 14 than than IN cord-006870-f5w6fw6q 4287 15 vehicle vehicle NN cord-006870-f5w6fw6q 4287 16 mice mouse NNS cord-006870-f5w6fw6q 4287 17 . . . cord-006870-f5w6fw6q 4288 1 Similar similar JJ cord-006870-f5w6fw6q 4288 2 results result NNS cord-006870-f5w6fw6q 4288 3 were be VBD cord-006870-f5w6fw6q 4288 4 seen see VBN cord-006870-f5w6fw6q 4288 5 with with IN cord-006870-f5w6fw6q 4288 6 7 7 CD cord-006870-f5w6fw6q 4288 7 daily daily JJ cord-006870-f5w6fw6q 4288 8 doses dose NNS cord-006870-f5w6fw6q 4288 9 of of IN cord-006870-f5w6fw6q 4288 10 1mg 1mg NNP cord-006870-f5w6fw6q 4288 11 / / SYM cord-006870-f5w6fw6q 4288 12 kg kg NN cord-006870-f5w6fw6q 4288 13 starting start VBG cord-006870-f5w6fw6q 4288 14 at at IN cord-006870-f5w6fw6q 4288 15 45 45 CD cord-006870-f5w6fw6q 4288 16 minutes minute NNS cord-006870-f5w6fw6q 4288 17 . . . cord-006870-f5w6fw6q 4289 1 Importantly importantly RB cord-006870-f5w6fw6q 4289 2 , , , cord-006870-f5w6fw6q 4289 3 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4289 4 is be VBZ cord-006870-f5w6fw6q 4289 5 not not RB cord-006870-f5w6fw6q 4289 6 an an DT cord-006870-f5w6fw6q 4289 7 anticonvulsant anticonvulsant JJ cord-006870-f5w6fw6q 4289 8 as as IN cord-006870-f5w6fw6q 4289 9 cvEEG cveeg JJ cord-006870-f5w6fw6q 4289 10 monitoring monitoring NN cord-006870-f5w6fw6q 4289 11 during during IN cord-006870-f5w6fw6q 4289 12 status status NN cord-006870-f5w6fw6q 4289 13 induction induction NN cord-006870-f5w6fw6q 4289 14 clearly clearly RB cord-006870-f5w6fw6q 4289 15 demonstrated demonstrate VBD cord-006870-f5w6fw6q 4289 16 that that IN cord-006870-f5w6fw6q 4289 17 seizures seizure NNS cord-006870-f5w6fw6q 4289 18 were be VBD cord-006870-f5w6fw6q 4289 19 not not RB cord-006870-f5w6fw6q 4289 20 stopped stop VBN cord-006870-f5w6fw6q 4289 21 or or CC cord-006870-f5w6fw6q 4289 22 reduced reduce VBN cord-006870-f5w6fw6q 4289 23 by by IN cord-006870-f5w6fw6q 4289 24 injection injection NN cord-006870-f5w6fw6q 4289 25 of of IN cord-006870-f5w6fw6q 4289 26 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4289 27 . . . cord-006870-f5w6fw6q 4290 1 These these DT cord-006870-f5w6fw6q 4290 2 results result NNS cord-006870-f5w6fw6q 4290 3 are be VBP cord-006870-f5w6fw6q 4290 4 consistent consistent JJ cord-006870-f5w6fw6q 4290 5 with with IN cord-006870-f5w6fw6q 4290 6 the the DT cord-006870-f5w6fw6q 4290 7 hypothesis hypothesis NN cord-006870-f5w6fw6q 4290 8 that that IN cord-006870-f5w6fw6q 4290 9 inflammation inflammation NN cord-006870-f5w6fw6q 4290 10 plays play VBZ cord-006870-f5w6fw6q 4290 11 an an DT cord-006870-f5w6fw6q 4290 12 important important JJ cord-006870-f5w6fw6q 4290 13 role role NN cord-006870-f5w6fw6q 4290 14 in in IN cord-006870-f5w6fw6q 4290 15 the the DT cord-006870-f5w6fw6q 4290 16 development development NN cord-006870-f5w6fw6q 4290 17 of of IN cord-006870-f5w6fw6q 4290 18 epilepsy epilepsy NN cord-006870-f5w6fw6q 4290 19 after after IN cord-006870-f5w6fw6q 4290 20 injury injury NN cord-006870-f5w6fw6q 4290 21 and and CC cord-006870-f5w6fw6q 4290 22 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 4290 23 treatments treatment NNS cord-006870-f5w6fw6q 4290 24 that that WDT cord-006870-f5w6fw6q 4290 25 target target VBP cord-006870-f5w6fw6q 4290 26 inflammation inflammation NN cord-006870-f5w6fw6q 4290 27 , , , cord-006870-f5w6fw6q 4290 28 like like IN cord-006870-f5w6fw6q 4290 29 CN-105 CN-105 NNP cord-006870-f5w6fw6q 4290 30 , , , cord-006870-f5w6fw6q 4290 31 can can MD cord-006870-f5w6fw6q 4290 32 prevent prevent VB cord-006870-f5w6fw6q 4290 33 and/or and/or CC cord-006870-f5w6fw6q 4290 34 reduce reduce VB cord-006870-f5w6fw6q 4290 35 the the DT cord-006870-f5w6fw6q 4290 36 development development NN cord-006870-f5w6fw6q 4290 37 of of IN cord-006870-f5w6fw6q 4290 38 epilepsy epilepsy NN cord-006870-f5w6fw6q 4290 39 . . . cord-006870-f5w6fw6q 4291 1 This this DT cord-006870-f5w6fw6q 4291 2 represents represent VBZ cord-006870-f5w6fw6q 4291 3 the the DT cord-006870-f5w6fw6q 4291 4 first first JJ cord-006870-f5w6fw6q 4291 5 therapy therapy NN cord-006870-f5w6fw6q 4291 6 to to TO cord-006870-f5w6fw6q 4291 7 prevent prevent VB cord-006870-f5w6fw6q 4291 8 the the DT cord-006870-f5w6fw6q 4291 9 development development NN cord-006870-f5w6fw6q 4291 10 of of IN cord-006870-f5w6fw6q 4291 11 epilepsy epilepsy NN cord-006870-f5w6fw6q 4291 12 that that WDT cord-006870-f5w6fw6q 4291 13 has have VBZ cord-006870-f5w6fw6q 4291 14 entered enter VBN cord-006870-f5w6fw6q 4291 15 into into IN cord-006870-f5w6fw6q 4291 16 clinical clinical JJ cord-006870-f5w6fw6q 4291 17 trials trial NNS cord-006870-f5w6fw6q 4291 18 . . . cord-006870-f5w6fw6q 4292 1 To to TO cord-006870-f5w6fw6q 4292 2 determine determine VB cord-006870-f5w6fw6q 4292 3 the the DT cord-006870-f5w6fw6q 4292 4 speed speed NN cord-006870-f5w6fw6q 4292 5 of of IN cord-006870-f5w6fw6q 4292 6 brain brain NN cord-006870-f5w6fw6q 4292 7 entrance entrance NN cord-006870-f5w6fw6q 4292 8 of of IN cord-006870-f5w6fw6q 4292 9 the the DT cord-006870-f5w6fw6q 4292 10 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 4292 11 drugs drug NNS cord-006870-f5w6fw6q 4292 12 ( ( -LRB- cord-006870-f5w6fw6q 4292 13 AEDs AEDs NNP cord-006870-f5w6fw6q 4292 14 ) ) -RRB- cord-006870-f5w6fw6q 4292 15 brivaracetam brivaracetam NNP cord-006870-f5w6fw6q 4292 16 ( ( -LRB- cord-006870-f5w6fw6q 4292 17 BRV BRV NNP cord-006870-f5w6fw6q 4292 18 ) ) -RRB- cord-006870-f5w6fw6q 4292 19 and and CC cord-006870-f5w6fw6q 4292 20 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 4292 21 ( ( -LRB- cord-006870-f5w6fw6q 4292 22 LEV LEV NNP cord-006870-f5w6fw6q 4292 23 ) ) -RRB- cord-006870-f5w6fw6q 4293 1 after after IN cord-006870-f5w6fw6q 4293 2 single single JJ cord-006870-f5w6fw6q 4293 3 intravenous intravenous JJ cord-006870-f5w6fw6q 4293 4 dosing dosing NN cord-006870-f5w6fw6q 4293 5 in in IN cord-006870-f5w6fw6q 4293 6 humans human NNS cord-006870-f5w6fw6q 4293 7 . . . cord-006870-f5w6fw6q 4294 1 BRV BRV NNP cord-006870-f5w6fw6q 4294 2 and and CC cord-006870-f5w6fw6q 4294 3 LEV LEV NNP cord-006870-f5w6fw6q 4294 4 both both DT cord-006870-f5w6fw6q 4294 5 bind bind VBP cord-006870-f5w6fw6q 4294 6 to to IN cord-006870-f5w6fw6q 4294 7 synaptic synaptic JJ cord-006870-f5w6fw6q 4294 8 vesicle vesicle NN cord-006870-f5w6fw6q 4294 9 protein protein NN cord-006870-f5w6fw6q 4294 10 2A 2a CD cord-006870-f5w6fw6q 4294 11 ( ( -LRB- cord-006870-f5w6fw6q 4294 12 SV2A SV2A NNP cord-006870-f5w6fw6q 4294 13 ) ) -RRB- cord-006870-f5w6fw6q 4294 14 , , , cord-006870-f5w6fw6q 4294 15 but but CC cord-006870-f5w6fw6q 4294 16 BRV BRV NNP cord-006870-f5w6fw6q 4294 17 has have VBZ cord-006870-f5w6fw6q 4294 18 more more RBR cord-006870-f5w6fw6q 4294 19 rapid rapid JJ cord-006870-f5w6fw6q 4294 20 brain brain NN cord-006870-f5w6fw6q 4294 21 entry entry NN cord-006870-f5w6fw6q 4294 22 than than IN cord-006870-f5w6fw6q 4294 23 LEV LEV NNP cord-006870-f5w6fw6q 4294 24 in in IN cord-006870-f5w6fw6q 4294 25 mice mouse NNS cord-006870-f5w6fw6q 4294 26 and and CC cord-006870-f5w6fw6q 4294 27 monkeys monkey NNS cord-006870-f5w6fw6q 4294 28 [ [ -LRB- cord-006870-f5w6fw6q 4294 29 1 1 CD cord-006870-f5w6fw6q 4294 30 ] ] -RRB- cord-006870-f5w6fw6q 4294 31 . . . cord-006870-f5w6fw6q 4295 1 SV2A SV2A NNP cord-006870-f5w6fw6q 4295 2 can can MD cord-006870-f5w6fw6q 4295 3 be be VB cord-006870-f5w6fw6q 4295 4 quantified quantify VBN cord-006870-f5w6fw6q 4295 5 in in IN cord-006870-f5w6fw6q 4295 6 the the DT cord-006870-f5w6fw6q 4295 7 living live VBG cord-006870-f5w6fw6q 4295 8 human human JJ cord-006870-f5w6fw6q 4295 9 brain brain NN cord-006870-f5w6fw6q 4295 10 using use VBG cord-006870-f5w6fw6q 4295 11 PET pet JJ cord-006870-f5w6fw6q 4295 12 imaging imaging NN cord-006870-f5w6fw6q 4295 13 with with IN cord-006870-f5w6fw6q 4295 14 [ [ -LRB- cord-006870-f5w6fw6q 4295 15 11C]UCB 11C]UCB NNP cord-006870-f5w6fw6q 4295 16 - - HYPH cord-006870-f5w6fw6q 4295 17 J[2 j[2 NN cord-006870-f5w6fw6q 4295 18 ] ] -RRB- cord-006870-f5w6fw6q 4295 19 . . . cord-006870-f5w6fw6q 4296 1 PET PET NNP cord-006870-f5w6fw6q 4296 2 scans scan NNS cord-006870-f5w6fw6q 4296 3 ( ( -LRB- cord-006870-f5w6fw6q 4296 4 n=13 n=13 NNP cord-006870-f5w6fw6q 4296 5 ) ) -RRB- cord-006870-f5w6fw6q 4296 6 were be VBD cord-006870-f5w6fw6q 4296 7 performed perform VBN cord-006870-f5w6fw6q 4296 8 with with IN cord-006870-f5w6fw6q 4296 9 [ [ -LRB- cord-006870-f5w6fw6q 4296 10 11C]UCB 11C]UCB NNP cord-006870-f5w6fw6q 4296 11 - - HYPH cord-006870-f5w6fw6q 4296 12 J J NNP cord-006870-f5w6fw6q 4296 13 administered administer VBN cord-006870-f5w6fw6q 4296 14 by by IN cord-006870-f5w6fw6q 4296 15 a a DT cord-006870-f5w6fw6q 4296 16 bolus bolus NN cord-006870-f5w6fw6q 4296 17 - - HYPH cord-006870-f5w6fw6q 4296 18 infusion infusion NN cord-006870-f5w6fw6q 4296 19 protocol protocol NN cord-006870-f5w6fw6q 4296 20 in in IN cord-006870-f5w6fw6q 4296 21 healthy healthy JJ cord-006870-f5w6fw6q 4296 22 volunteers volunteer NNS cord-006870-f5w6fw6q 4296 23 ( ( -LRB- cord-006870-f5w6fw6q 4296 24 n=9 n=9 NN cord-006870-f5w6fw6q 4296 25 ) ) -RRB- cord-006870-f5w6fw6q 4296 26 . . . cord-006870-f5w6fw6q 4297 1 Therapeutic therapeutic JJ cord-006870-f5w6fw6q 4297 2 dosages dosage NNS cord-006870-f5w6fw6q 4297 3 of of IN cord-006870-f5w6fw6q 4297 4 BRV BRV NNP cord-006870-f5w6fw6q 4297 5 ( ( -LRB- cord-006870-f5w6fw6q 4297 6 50 50 CD cord-006870-f5w6fw6q 4297 7 mg mg NNS cord-006870-f5w6fw6q 4297 8 , , , cord-006870-f5w6fw6q 4297 9 n=1 n=1 FW cord-006870-f5w6fw6q 4297 10 ; ; : cord-006870-f5w6fw6q 4297 11 100 100 CD cord-006870-f5w6fw6q 4297 12 mg mg NNS cord-006870-f5w6fw6q 4297 13 , , , cord-006870-f5w6fw6q 4297 14 n=4 n=4 JJ cord-006870-f5w6fw6q 4297 15 ; ; : cord-006870-f5w6fw6q 4297 16 or or CC cord-006870-f5w6fw6q 4297 17 200 200 CD cord-006870-f5w6fw6q 4297 18 mg mg NNS cord-006870-f5w6fw6q 4297 19 , , , cord-006870-f5w6fw6q 4297 20 n=2 n=2 NNS cord-006870-f5w6fw6q 4297 21 ) ) -RRB- cord-006870-f5w6fw6q 4297 22 or or CC cord-006870-f5w6fw6q 4297 23 LEV LEV NNP cord-006870-f5w6fw6q 4297 24 ( ( -LRB- cord-006870-f5w6fw6q 4297 25 1500 1500 CD cord-006870-f5w6fw6q 4297 26 mg mg NNP cord-006870-f5w6fw6q 4297 27 , , , cord-006870-f5w6fw6q 4297 28 n=6 n=6 NN cord-006870-f5w6fw6q 4297 29 ) ) -RRB- cord-006870-f5w6fw6q 4297 30 were be VBD cord-006870-f5w6fw6q 4297 31 administered administer VBN cord-006870-f5w6fw6q 4297 32 as as IN cord-006870-f5w6fw6q 4297 33 5-minute 5-minute CD cord-006870-f5w6fw6q 4297 34 intravenous intravenous JJ cord-006870-f5w6fw6q 4297 35 infusions infusion NNS cord-006870-f5w6fw6q 4297 36 60 60 CD cord-006870-f5w6fw6q 4297 37 minutes minute NNS cord-006870-f5w6fw6q 4297 38 after after IN cord-006870-f5w6fw6q 4297 39 the the DT cord-006870-f5w6fw6q 4297 40 start start NN cord-006870-f5w6fw6q 4297 41 of of IN cord-006870-f5w6fw6q 4297 42 the the DT cord-006870-f5w6fw6q 4297 43 first first JJ cord-006870-f5w6fw6q 4297 44 PET pet NN cord-006870-f5w6fw6q 4297 45 scan scan NN cord-006870-f5w6fw6q 4297 46 . . . cord-006870-f5w6fw6q 4298 1 Tracer tracer NN cord-006870-f5w6fw6q 4298 2 displacement displacement NN cord-006870-f5w6fw6q 4298 3 half half JJ cord-006870-f5w6fw6q 4298 4 - - HYPH cord-006870-f5w6fw6q 4298 5 times time NNS cord-006870-f5w6fw6q 4298 6 were be VBD cord-006870-f5w6fw6q 4298 7 determined determine VBN cord-006870-f5w6fw6q 4298 8 by by IN cord-006870-f5w6fw6q 4298 9 subtracting subtract VBG cord-006870-f5w6fw6q 4298 10 the the DT cord-006870-f5w6fw6q 4298 11 radioligand radioligand JJ cord-006870-f5w6fw6q 4298 12 clearance clearance NN cord-006870-f5w6fw6q 4298 13 halftime halftime NN cord-006870-f5w6fw6q 4298 14 from from IN cord-006870-f5w6fw6q 4298 15 the the DT cord-006870-f5w6fw6q 4298 16 radioligand radioligand JJ cord-006870-f5w6fw6q 4298 17 displacement displacement NN cord-006870-f5w6fw6q 4298 18 half half JJ cord-006870-f5w6fw6q 4298 19 - - HYPH cord-006870-f5w6fw6q 4298 20 times time NNS cord-006870-f5w6fw6q 4298 21 estimated estimate VBN cord-006870-f5w6fw6q 4298 22 by by IN cord-006870-f5w6fw6q 4298 23 exponential exponential JJ cord-006870-f5w6fw6q 4298 24 fitting fitting NN cord-006870-f5w6fw6q 4298 25 of of IN cord-006870-f5w6fw6q 4298 26 the the DT cord-006870-f5w6fw6q 4298 27 post post JJ cord-006870-f5w6fw6q 4298 28 - - JJ cord-006870-f5w6fw6q 4298 29 AED aed JJ cord-006870-f5w6fw6q 4298 30 drop drop NN cord-006870-f5w6fw6q 4298 31 in in IN cord-006870-f5w6fw6q 4298 32 distribution distribution NN cord-006870-f5w6fw6q 4298 33 volumes volume NNS cord-006870-f5w6fw6q 4298 34 ( ( -LRB- cord-006870-f5w6fw6q 4298 35 VT VT NNP cord-006870-f5w6fw6q 4298 36 ) ) -RRB- cord-006870-f5w6fw6q 4298 37 . . . cord-006870-f5w6fw6q 4299 1 Data datum NNS cord-006870-f5w6fw6q 4299 2 were be VBD cord-006870-f5w6fw6q 4299 3 also also RB cord-006870-f5w6fw6q 4299 4 analyzed analyze VBN cord-006870-f5w6fw6q 4299 5 using use VBG cord-006870-f5w6fw6q 4299 6 an an DT cord-006870-f5w6fw6q 4299 7 advanced advanced JJ cord-006870-f5w6fw6q 4299 8 mathematical mathematical JJ cord-006870-f5w6fw6q 4299 9 model model NN cord-006870-f5w6fw6q 4299 10 that that WDT cord-006870-f5w6fw6q 4299 11 described describe VBD cord-006870-f5w6fw6q 4299 12 the the DT cord-006870-f5w6fw6q 4299 13 relationship relationship NN cord-006870-f5w6fw6q 4299 14 between between IN cord-006870-f5w6fw6q 4299 15 brain brain NN cord-006870-f5w6fw6q 4299 16 [ [ -LRB- cord-006870-f5w6fw6q 4299 17 11C]UCB 11C]UCB NNP cord-006870-f5w6fw6q 4299 18 - - HYPH cord-006870-f5w6fw6q 4299 19 J J NNP cord-006870-f5w6fw6q 4299 20 PET PET NNP cord-006870-f5w6fw6q 4299 21 data datum NNS cord-006870-f5w6fw6q 4299 22 and and CC cord-006870-f5w6fw6q 4299 23 time time NN cord-006870-f5w6fw6q 4299 24 - - HYPH cord-006870-f5w6fw6q 4299 25 varying vary VBG cord-006870-f5w6fw6q 4299 26 AED AED NNP cord-006870-f5w6fw6q 4299 27 plasma plasma NN cord-006870-f5w6fw6q 4299 28 curves curve NNS cord-006870-f5w6fw6q 4299 29 to to TO cord-006870-f5w6fw6q 4299 30 directly directly RB cord-006870-f5w6fw6q 4299 31 estimate estimate VB cord-006870-f5w6fw6q 4299 32 brain brain NN cord-006870-f5w6fw6q 4299 33 entrance entrance NN cord-006870-f5w6fw6q 4299 34 ( ( -LRB- cord-006870-f5w6fw6q 4299 35 K1 K1 NNP cord-006870-f5w6fw6q 4299 36 ) ) -RRB- cord-006870-f5w6fw6q 4299 37 of of IN cord-006870-f5w6fw6q 4299 38 both both DT cord-006870-f5w6fw6q 4299 39 AEDs aed NNS cord-006870-f5w6fw6q 4299 40 and and CC cord-006870-f5w6fw6q 4299 41 [ [ -LRB- cord-006870-f5w6fw6q 4299 42 11C]UCB 11C]UCB NNP cord-006870-f5w6fw6q 4299 43 - - HYPH cord-006870-f5w6fw6q 4299 44 J J NNP cord-006870-f5w6fw6q 4299 45 , , , cord-006870-f5w6fw6q 4299 46 free free JJ cord-006870-f5w6fw6q 4299 47 fraction fraction NN cord-006870-f5w6fw6q 4299 48 of of IN cord-006870-f5w6fw6q 4299 49 [ [ -LRB- cord-006870-f5w6fw6q 4299 50 11C]UCB 11C]UCB NNP cord-006870-f5w6fw6q 4299 51 - - HYPH cord-006870-f5w6fw6q 4299 52 J J NNP cord-006870-f5w6fw6q 4299 53 in in IN cord-006870-f5w6fw6q 4299 54 the the DT cord-006870-f5w6fw6q 4299 55 brain brain NN cord-006870-f5w6fw6q 4299 56 , , , cord-006870-f5w6fw6q 4299 57 and and CC cord-006870-f5w6fw6q 4299 58 VT VT NNP cord-006870-f5w6fw6q 4299 59 values value NNS cord-006870-f5w6fw6q 4299 60 . . . cord-006870-f5w6fw6q 4300 1 The the DT cord-006870-f5w6fw6q 4300 2 radioligand radioligand JJ cord-006870-f5w6fw6q 4300 3 clearance clearance NN cord-006870-f5w6fw6q 4300 4 half half JJ cord-006870-f5w6fw6q 4300 5 - - HYPH cord-006870-f5w6fw6q 4300 6 time time NN cord-006870-f5w6fw6q 4300 7 was be VBD cord-006870-f5w6fw6q 4300 8 8 8 CD cord-006870-f5w6fw6q 4300 9 minutes minute NNS cord-006870-f5w6fw6q 4300 10 . . . cord-006870-f5w6fw6q 4301 1 Tracer tracer NN cord-006870-f5w6fw6q 4301 2 displacement displacement NN cord-006870-f5w6fw6q 4301 3 half half JJ cord-006870-f5w6fw6q 4301 4 - - HYPH cord-006870-f5w6fw6q 4301 5 times time NNS cord-006870-f5w6fw6q 4301 6 were be VBD cord-006870-f5w6fw6q 4301 7 1.7 1.7 CD cord-006870-f5w6fw6q 4301 8 and and CC cord-006870-f5w6fw6q 4301 9 2.1 2.1 CD cord-006870-f5w6fw6q 4301 10 minutes minute NNS cord-006870-f5w6fw6q 4301 11 for for IN cord-006870-f5w6fw6q 4301 12 BRV BRV NNP cord-006870-f5w6fw6q 4301 13 200 200 CD cord-006870-f5w6fw6q 4301 14 mg mg NNP cord-006870-f5w6fw6q 4301 15 , , , cord-006870-f5w6fw6q 4301 16 and and CC cord-006870-f5w6fw6q 4301 17 20 20 CD cord-006870-f5w6fw6q 4301 18 ±6 ±6 NN cord-006870-f5w6fw6q 4301 19 minutes minute NNS cord-006870-f5w6fw6q 4301 20 for for IN cord-006870-f5w6fw6q 4301 21 LEV LEV NNP cord-006870-f5w6fw6q 4301 22 1500 1500 CD cord-006870-f5w6fw6q 4301 23 mg mg NN cord-006870-f5w6fw6q 4301 24 . . . cord-006870-f5w6fw6q 4302 1 Lower low JJR cord-006870-f5w6fw6q 4302 2 BRV BRV NNP cord-006870-f5w6fw6q 4302 3 doses dose NNS cord-006870-f5w6fw6q 4302 4 had have VBD cord-006870-f5w6fw6q 4302 5 longer long JJR cord-006870-f5w6fw6q 4302 6 half half JJ cord-006870-f5w6fw6q 4302 7 - - HYPH cord-006870-f5w6fw6q 4302 8 times time NNS cord-006870-f5w6fw6q 4302 9 , , , cord-006870-f5w6fw6q 4302 10 but but CC cord-006870-f5w6fw6q 4302 11 values value NNS cord-006870-f5w6fw6q 4302 12 were be VBD cord-006870-f5w6fw6q 4302 13 misleading misleading JJ cord-006870-f5w6fw6q 4302 14 as as IN cord-006870-f5w6fw6q 4302 15 they -PRON- PRP cord-006870-f5w6fw6q 4302 16 assumed assume VBD cord-006870-f5w6fw6q 4302 17 100 100 CD cord-006870-f5w6fw6q 4302 18 % % NN cord-006870-f5w6fw6q 4302 19 SV2A sv2a NN cord-006870-f5w6fw6q 4302 20 occupancy occupancy NN cord-006870-f5w6fw6q 4302 21 . . . cord-006870-f5w6fw6q 4303 1 The the DT cord-006870-f5w6fw6q 4303 2 advanced advanced JJ cord-006870-f5w6fw6q 4303 3 compartment compartment NN cord-006870-f5w6fw6q 4303 4 model model NN cord-006870-f5w6fw6q 4303 5 described describe VBD cord-006870-f5w6fw6q 4303 6 well well RB cord-006870-f5w6fw6q 4303 7 -dose -dose HYPH cord-006870-f5w6fw6q 4303 8 scans scan NNS cord-006870-f5w6fw6q 4303 9 . . . cord-006870-f5w6fw6q 4304 1 Using use VBG cord-006870-f5w6fw6q 4304 2 the the DT cord-006870-f5w6fw6q 4304 3 advanced advanced JJ cord-006870-f5w6fw6q 4304 4 model model NN cord-006870-f5w6fw6q 4304 5 , , , cord-006870-f5w6fw6q 4304 6 the the DT cord-006870-f5w6fw6q 4304 7 BRV BRV NNP cord-006870-f5w6fw6q 4304 8 uptake uptake NN cord-006870-f5w6fw6q 4304 9 rate rate NN cord-006870-f5w6fw6q 4304 10 ( ( -LRB- cord-006870-f5w6fw6q 4304 11 ~50 ~50 NFP cord-006870-f5w6fw6q 4304 12 uL uL NNP cord-006870-f5w6fw6q 4304 13 / / SYM cord-006870-f5w6fw6q 4304 14 min min NNP cord-006870-f5w6fw6q 4304 15 / / SYM cord-006870-f5w6fw6q 4304 16 cm3 cm3 NNP cord-006870-f5w6fw6q 4304 17 ) ) -RRB- cord-006870-f5w6fw6q 4304 18 was be VBD cord-006870-f5w6fw6q 4304 19 found find VBN cord-006870-f5w6fw6q 4304 20 to to TO cord-006870-f5w6fw6q 4304 21 be be VB cord-006870-f5w6fw6q 4304 22 at at IN cord-006870-f5w6fw6q 4304 23 least least JJS cord-006870-f5w6fw6q 4304 24 8-fold 8-fold CD cord-006870-f5w6fw6q 4304 25 higher high JJR cord-006870-f5w6fw6q 4304 26 than than IN cord-006870-f5w6fw6q 4304 27 that that DT cord-006870-f5w6fw6q 4304 28 of of IN cord-006870-f5w6fw6q 4304 29 LEV LEV NNP cord-006870-f5w6fw6q 4304 30 ( ( -LRB- cord-006870-f5w6fw6q 4304 31 ~6 ~6 NFP cord-006870-f5w6fw6q 4304 32 uL uL NNP cord-006870-f5w6fw6q 4304 33 / / SYM cord-006870-f5w6fw6q 4304 34 min min NN cord-006870-f5w6fw6q 4304 35 / / SYM cord-006870-f5w6fw6q 4304 36 cm3 cm3 NNP cord-006870-f5w6fw6q 4304 37 ) ) -RRB- cord-006870-f5w6fw6q 4304 38 . . . cord-006870-f5w6fw6q 4305 1 The the DT cord-006870-f5w6fw6q 4305 2 results result NNS cord-006870-f5w6fw6q 4305 3 demonstrate demonstrate VBP cord-006870-f5w6fw6q 4305 4 that that IN cord-006870-f5w6fw6q 4305 5 BRV BRV NNP cord-006870-f5w6fw6q 4305 6 enters enter VBZ cord-006870-f5w6fw6q 4305 7 the the DT cord-006870-f5w6fw6q 4305 8 human human JJ cord-006870-f5w6fw6q 4305 9 brain brain NN cord-006870-f5w6fw6q 4305 10 faster fast RBR cord-006870-f5w6fw6q 4305 11 than than IN cord-006870-f5w6fw6q 4305 12 LEV LEV NNP cord-006870-f5w6fw6q 4305 13 . . . cord-006870-f5w6fw6q 4306 1 The the DT cord-006870-f5w6fw6q 4306 2 potential potential JJ cord-006870-f5w6fw6q 4306 3 therapeutic therapeutic JJ cord-006870-f5w6fw6q 4306 4 benefit benefit NN cord-006870-f5w6fw6q 4306 5 of of IN cord-006870-f5w6fw6q 4306 6 this this DT cord-006870-f5w6fw6q 4306 7 has have VBZ cord-006870-f5w6fw6q 4306 8 yet yet RB cord-006870-f5w6fw6q 4306 9 to to TO cord-006870-f5w6fw6q 4306 10 be be VB cord-006870-f5w6fw6q 4306 11 determined determine VBN cord-006870-f5w6fw6q 4306 12 . . . cord-006870-f5w6fw6q 4306 13 _SP cord-006870-f5w6fw6q 4307 1 While while IN cord-006870-f5w6fw6q 4307 2 intravenous intravenous JJ cord-006870-f5w6fw6q 4307 3 anesthetic anesthetic NN cord-006870-f5w6fw6q 4307 4 therapy therapy NN cord-006870-f5w6fw6q 4307 5 ( ( -LRB- cord-006870-f5w6fw6q 4307 6 IVAT IVAT NNP cord-006870-f5w6fw6q 4307 7 ) ) -RRB- cord-006870-f5w6fw6q 4307 8 represents represent VBZ cord-006870-f5w6fw6q 4307 9 the the DT cord-006870-f5w6fw6q 4307 10 gold gold NN cord-006870-f5w6fw6q 4307 11 - - HYPH cord-006870-f5w6fw6q 4307 12 standard standard NN cord-006870-f5w6fw6q 4307 13 for for IN cord-006870-f5w6fw6q 4307 14 treatment treatment NN cord-006870-f5w6fw6q 4307 15 of of IN cord-006870-f5w6fw6q 4307 16 refractory refractory JJ cord-006870-f5w6fw6q 4307 17 status status NN cord-006870-f5w6fw6q 4307 18 epilepticus epilepticus NN cord-006870-f5w6fw6q 4307 19 ( ( -LRB- cord-006870-f5w6fw6q 4307 20 RSE RSE NNP cord-006870-f5w6fw6q 4307 21 ) ) -RRB- cord-006870-f5w6fw6q 4307 22 , , , cord-006870-f5w6fw6q 4307 23 the the DT cord-006870-f5w6fw6q 4307 24 optimal optimal JJ cord-006870-f5w6fw6q 4307 25 depth depth NN cord-006870-f5w6fw6q 4307 26 and and CC cord-006870-f5w6fw6q 4307 27 duration duration NN cord-006870-f5w6fw6q 4307 28 of of IN cord-006870-f5w6fw6q 4307 29 therapy therapy NN cord-006870-f5w6fw6q 4307 30 is be VBZ cord-006870-f5w6fw6q 4307 31 not not RB cord-006870-f5w6fw6q 4307 32 known know VBN cord-006870-f5w6fw6q 4307 33 . . . cord-006870-f5w6fw6q 4308 1 The the DT cord-006870-f5w6fw6q 4308 2 goal goal NN cord-006870-f5w6fw6q 4308 3 of of IN cord-006870-f5w6fw6q 4308 4 this this DT cord-006870-f5w6fw6q 4308 5 retrospective retrospective JJ cord-006870-f5w6fw6q 4308 6 observational observational JJ cord-006870-f5w6fw6q 4308 7 study study NN cord-006870-f5w6fw6q 4308 8 was be VBD cord-006870-f5w6fw6q 4308 9 to to TO cord-006870-f5w6fw6q 4308 10 describe describe VB cord-006870-f5w6fw6q 4308 11 the the DT cord-006870-f5w6fw6q 4308 12 relationship relationship NN cord-006870-f5w6fw6q 4308 13 between between IN cord-006870-f5w6fw6q 4308 14 the the DT cord-006870-f5w6fw6q 4308 15 depth depth NN cord-006870-f5w6fw6q 4308 16 of of IN cord-006870-f5w6fw6q 4308 17 burst burst NN cord-006870-f5w6fw6q 4308 18 suppression suppression NN cord-006870-f5w6fw6q 4308 19 and and CC cord-006870-f5w6fw6q 4308 20 the the DT cord-006870-f5w6fw6q 4308 21 ability ability NN cord-006870-f5w6fw6q 4308 22 to to TO cord-006870-f5w6fw6q 4308 23 successfully successfully RB cord-006870-f5w6fw6q 4308 24 wean wean VB cord-006870-f5w6fw6q 4308 25 IVAT IVAT NNP cord-006870-f5w6fw6q 4308 26 during during IN cord-006870-f5w6fw6q 4308 27 RSE rse NN cord-006870-f5w6fw6q 4308 28 treatment treatment NN cord-006870-f5w6fw6q 4308 29 . . . cord-006870-f5w6fw6q 4309 1 Fifty fifty CD cord-006870-f5w6fw6q 4309 2 patients patient NNS cord-006870-f5w6fw6q 4309 3 were be VBD cord-006870-f5w6fw6q 4309 4 identified identify VBN cord-006870-f5w6fw6q 4309 5 with with IN cord-006870-f5w6fw6q 4309 6 RSE RSE NNP cord-006870-f5w6fw6q 4309 7 who who WP cord-006870-f5w6fw6q 4309 8 underwent undergo VBD cord-006870-f5w6fw6q 4309 9 continuous continuous JJ cord-006870-f5w6fw6q 4309 10 electroencephalography electroencephalography NN cord-006870-f5w6fw6q 4309 11 . . . cord-006870-f5w6fw6q 4310 1 Using use VBG cord-006870-f5w6fw6q 4310 2 Persyst Persyst NNP cord-006870-f5w6fw6q 4310 3 , , , cord-006870-f5w6fw6q 4310 4 the the DT cord-006870-f5w6fw6q 4310 5 suppression suppression NN cord-006870-f5w6fw6q 4310 6 ratio ratio NN cord-006870-f5w6fw6q 4310 7 ( ( -LRB- cord-006870-f5w6fw6q 4310 8 SR SR NNP cord-006870-f5w6fw6q 4310 9 ) ) -RRB- cord-006870-f5w6fw6q 4310 10 was be VBD cord-006870-f5w6fw6q 4310 11 calculated calculate VBN cord-006870-f5w6fw6q 4310 12 up up RP cord-006870-f5w6fw6q 4310 13 to to TO cord-006870-f5w6fw6q 4310 14 72 72 CD cord-006870-f5w6fw6q 4310 15 hours hour NNS cord-006870-f5w6fw6q 4310 16 prior prior RB cord-006870-f5w6fw6q 4310 17 to to IN cord-006870-f5w6fw6q 4310 18 weaning wean VBG cord-006870-f5w6fw6q 4310 19 IVAT IVAT NNP cord-006870-f5w6fw6q 4310 20 . . . cord-006870-f5w6fw6q 4311 1 The the DT cord-006870-f5w6fw6q 4311 2 type type NN cord-006870-f5w6fw6q 4311 3 and and CC cord-006870-f5w6fw6q 4311 4 duration duration NN cord-006870-f5w6fw6q 4311 5 of of IN cord-006870-f5w6fw6q 4311 6 IVAT IVAT NNP cord-006870-f5w6fw6q 4311 7 was be VBD cord-006870-f5w6fw6q 4311 8 recorded record VBN cord-006870-f5w6fw6q 4311 9 , , , cord-006870-f5w6fw6q 4311 10 as as RB cord-006870-f5w6fw6q 4311 11 well well RB cord-006870-f5w6fw6q 4311 12 as as IN cord-006870-f5w6fw6q 4311 13 complications complication NNS cord-006870-f5w6fw6q 4311 14 . . . cord-006870-f5w6fw6q 4312 1 We -PRON- PRP cord-006870-f5w6fw6q 4312 2 compared compare VBD cord-006870-f5w6fw6q 4312 3 these these DT cord-006870-f5w6fw6q 4312 4 variables variable NNS cord-006870-f5w6fw6q 4312 5 between between IN cord-006870-f5w6fw6q 4312 6 successful successful JJ cord-006870-f5w6fw6q 4312 7 and and CC cord-006870-f5w6fw6q 4312 8 unsuccessful unsuccessful JJ cord-006870-f5w6fw6q 4312 9 weans wean NNS cord-006870-f5w6fw6q 4312 10 . . . cord-006870-f5w6fw6q 4313 1 The the DT cord-006870-f5w6fw6q 4313 2 mean mean JJ cord-006870-f5w6fw6q 4313 3 SR SR NNP cord-006870-f5w6fw6q 4313 4 for for IN cord-006870-f5w6fw6q 4313 5 all all DT cord-006870-f5w6fw6q 4313 6 patients patient NNS cord-006870-f5w6fw6q 4313 7 was be VBD cord-006870-f5w6fw6q 4313 8 19.0±26.3 19.0±26.3 CD cord-006870-f5w6fw6q 4313 9 % % NN cord-006870-f5w6fw6q 4313 10 , , , cord-006870-f5w6fw6q 4313 11 with with IN cord-006870-f5w6fw6q 4313 12 a a DT cord-006870-f5w6fw6q 4313 13 mean mean JJ cord-006870-f5w6fw6q 4313 14 treatment treatment NN cord-006870-f5w6fw6q 4313 15 duration duration NN cord-006870-f5w6fw6q 4313 16 of of IN cord-006870-f5w6fw6q 4313 17 63.3±42.1 63.3±42.1 CD cord-006870-f5w6fw6q 4313 18 hours hour NNS cord-006870-f5w6fw6q 4313 19 . . . cord-006870-f5w6fw6q 4314 1 There there EX cord-006870-f5w6fw6q 4314 2 was be VBD cord-006870-f5w6fw6q 4314 3 no no DT cord-006870-f5w6fw6q 4314 4 difference difference NN cord-006870-f5w6fw6q 4314 5 in in IN cord-006870-f5w6fw6q 4314 6 treatment treatment NN cord-006870-f5w6fw6q 4314 7 duration duration NN cord-006870-f5w6fw6q 4314 8 between between IN cord-006870-f5w6fw6q 4314 9 successful successful JJ cord-006870-f5w6fw6q 4314 10 and and CC cord-006870-f5w6fw6q 4314 11 unsuccessful unsuccessful JJ cord-006870-f5w6fw6q 4314 12 weans(p=0.54 weans(p=0.54 NNP cord-006870-f5w6fw6q 4314 13 ) ) -RRB- cord-006870-f5w6fw6q 4314 14 , , , cord-006870-f5w6fw6q 4314 15 but but CC cord-006870-f5w6fw6q 4314 16 SR SR NNP cord-006870-f5w6fw6q 4314 17 was be VBD cord-006870-f5w6fw6q 4314 18 significantly significantly RB cord-006870-f5w6fw6q 4314 19 lower low JJR cord-006870-f5w6fw6q 4314 20 in in IN cord-006870-f5w6fw6q 4314 21 successful successful JJ cord-006870-f5w6fw6q 4314 22 weans wean NNS cord-006870-f5w6fw6q 4314 23 ( ( -LRB- cord-006870-f5w6fw6q 4314 24 10.0±15.2 10.0±15.2 CD cord-006870-f5w6fw6q 4314 25 % % NN cord-006870-f5w6fw6q 4314 26 vs vs IN cord-006870-f5w6fw6q 4314 27 27.9±33.4 27.9±33.4 CD cord-006870-f5w6fw6q 4314 28 % % NN cord-006870-f5w6fw6q 4314 29 , , , cord-006870-f5w6fw6q 4314 30 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 4314 31 ) ) -RRB- cord-006870-f5w6fw6q 4314 32 . . . cord-006870-f5w6fw6q 4315 1 The the DT cord-006870-f5w6fw6q 4315 2 receiver receiver NN cord-006870-f5w6fw6q 4315 3 operating operating NN cord-006870-f5w6fw6q 4315 4 curve curve NN cord-006870-f5w6fw6q 4315 5 ( ( -LRB- cord-006870-f5w6fw6q 4315 6 ROC ROC NNP cord-006870-f5w6fw6q 4315 7 ) ) -RRB- cord-006870-f5w6fw6q 4315 8 for for IN cord-006870-f5w6fw6q 4315 9 the the DT cord-006870-f5w6fw6q 4315 10 sensitivity sensitivity NN cord-006870-f5w6fw6q 4315 11 and and CC cord-006870-f5w6fw6q 4315 12 specificity specificity NN cord-006870-f5w6fw6q 4315 13 of of IN cord-006870-f5w6fw6q 4315 14 the the DT cord-006870-f5w6fw6q 4315 15 mean mean JJ cord-006870-f5w6fw6q 4315 16 SR SR NNP cord-006870-f5w6fw6q 4315 17 to to TO cord-006870-f5w6fw6q 4315 18 predict predict VB cord-006870-f5w6fw6q 4315 19 a a DT cord-006870-f5w6fw6q 4315 20 successful successful JJ cord-006870-f5w6fw6q 4315 21 weaning weaning NN cord-006870-f5w6fw6q 4315 22 attempt attempt NN cord-006870-f5w6fw6q 4315 23 did do VBD cord-006870-f5w6fw6q 4315 24 not not RB cord-006870-f5w6fw6q 4315 25 identify identify VB cord-006870-f5w6fw6q 4315 26 a a DT cord-006870-f5w6fw6q 4315 27 threshold threshold NN cord-006870-f5w6fw6q 4315 28 to to TO cord-006870-f5w6fw6q 4315 29 predict predict VB cord-006870-f5w6fw6q 4315 30 weaning wean VBG cord-006870-f5w6fw6q 4315 31 success success NN cord-006870-f5w6fw6q 4315 32 . . . cord-006870-f5w6fw6q 4316 1 The the DT cord-006870-f5w6fw6q 4316 2 use use NN cord-006870-f5w6fw6q 4316 3 of of IN cord-006870-f5w6fw6q 4316 4 pentobarbital pentobarbital NN cord-006870-f5w6fw6q 4316 5 was be VBD cord-006870-f5w6fw6q 4316 6 associated associate VBN cord-006870-f5w6fw6q 4316 7 with with IN cord-006870-f5w6fw6q 4316 8 a a DT cord-006870-f5w6fw6q 4316 9 significantly significantly RB cord-006870-f5w6fw6q 4316 10 higher high JJR cord-006870-f5w6fw6q 4316 11 SR SR NNP cord-006870-f5w6fw6q 4316 12 when when WRB cord-006870-f5w6fw6q 4316 13 compared compare VBN cord-006870-f5w6fw6q 4316 14 to to IN cord-006870-f5w6fw6q 4316 15 midazolam midazolam NNP cord-006870-f5w6fw6q 4316 16 ( ( -LRB- cord-006870-f5w6fw6q 4316 17 69.1±18.9 69.1±18.9 CD cord-006870-f5w6fw6q 4316 18 % % NN cord-006870-f5w6fw6q 4316 19 vs vs IN cord-006870-f5w6fw6q 4316 20 6.9±8.2 6.9±8.2 CD cord-006870-f5w6fw6q 4316 21 % % NN cord-006870-f5w6fw6q 4316 22 , , , cord-006870-f5w6fw6q 4316 23 p p NN cord-006870-f5w6fw6q 4316 24 < < XX cord-006870-f5w6fw6q 4316 25 0.001 0.001 CD cord-006870-f5w6fw6q 4316 26 ) ) -RRB- cord-006870-f5w6fw6q 4316 27 . . . cord-006870-f5w6fw6q 4317 1 Patients patient NNS cord-006870-f5w6fw6q 4317 2 failed fail VBD cord-006870-f5w6fw6q 4317 3 IVAT IVAT NNP cord-006870-f5w6fw6q 4317 4 weaning wean VBG cord-006870-f5w6fw6q 4317 5 a a DT cord-006870-f5w6fw6q 4317 6 mean mean JJ cord-006870-f5w6fw6q 4317 7 24.5±22.6 24.5±22.6 CD cord-006870-f5w6fw6q 4317 8 hours hour NNS cord-006870-f5w6fw6q 4317 9 after after IN cord-006870-f5w6fw6q 4317 10 initiating initiate VBG cord-006870-f5w6fw6q 4317 11 the the DT cord-006870-f5w6fw6q 4317 12 IVAT IVAT NNP cord-006870-f5w6fw6q 4317 13 wean wean NN cord-006870-f5w6fw6q 4317 14 , , , cord-006870-f5w6fw6q 4317 15 which which WDT cord-006870-f5w6fw6q 4317 16 occurred occur VBD cord-006870-f5w6fw6q 4317 17 after after IN cord-006870-f5w6fw6q 4317 18 a a DT cord-006870-f5w6fw6q 4317 19 mean mean JJ cord-006870-f5w6fw6q 4317 20 decrease decrease NN cord-006870-f5w6fw6q 4317 21 in in IN cord-006870-f5w6fw6q 4317 22 the the DT cord-006870-f5w6fw6q 4317 23 midazolam midazolam NNP cord-006870-f5w6fw6q 4317 24 infusion infusion NN cord-006870-f5w6fw6q 4317 25 rate rate NN cord-006870-f5w6fw6q 4317 26 of of IN cord-006870-f5w6fw6q 4317 27 68 68 CD cord-006870-f5w6fw6q 4317 28 ± ± CD cord-006870-f5w6fw6q 4317 29 33 33 CD cord-006870-f5w6fw6q 4317 30 % % NN cord-006870-f5w6fw6q 4317 31 . . . cord-006870-f5w6fw6q 4318 1 Depth depth NN cord-006870-f5w6fw6q 4318 2 of of IN cord-006870-f5w6fw6q 4318 3 SR SR NNP cord-006870-f5w6fw6q 4318 4 was be VBD cord-006870-f5w6fw6q 4318 5 not not RB cord-006870-f5w6fw6q 4318 6 associated associate VBN cord-006870-f5w6fw6q 4318 7 with with IN cord-006870-f5w6fw6q 4318 8 infection infection NN cord-006870-f5w6fw6q 4318 9 risk risk NN cord-006870-f5w6fw6q 4318 10 ( ( -LRB- cord-006870-f5w6fw6q 4318 11 p=0.74 p=0.74 NNP cord-006870-f5w6fw6q 4318 12 ) ) -RRB- cord-006870-f5w6fw6q 4318 13 , , , cord-006870-f5w6fw6q 4318 14 but but CC cord-006870-f5w6fw6q 4318 15 was be VBD cord-006870-f5w6fw6q 4318 16 associated associate VBN cord-006870-f5w6fw6q 4318 17 with with IN cord-006870-f5w6fw6q 4318 18 the the DT cord-006870-f5w6fw6q 4318 19 need need NN cord-006870-f5w6fw6q 4318 20 for for IN cord-006870-f5w6fw6q 4318 21 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4318 22 ( ( -LRB- cord-006870-f5w6fw6q 4318 23 27.6±32.7 27.6±32.7 CD cord-006870-f5w6fw6q 4318 24 % % NN cord-006870-f5w6fw6q 4318 25 versus versus IN cord-006870-f5w6fw6q 4318 26 10.2±17.2 10.2±17.2 CD cord-006870-f5w6fw6q 4318 27 % % NN cord-006870-f5w6fw6q 4318 28 , , , cord-006870-f5w6fw6q 4318 29 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 4318 30 ) ) -RRB- cord-006870-f5w6fw6q 4318 31 . . . cord-006870-f5w6fw6q 4319 1 Vasopressors Vasopressors NNP cord-006870-f5w6fw6q 4319 2 were be VBD cord-006870-f5w6fw6q 4319 3 required require VBN cord-006870-f5w6fw6q 4319 4 in in IN cord-006870-f5w6fw6q 4319 5 87.5 87.5 CD cord-006870-f5w6fw6q 4319 6 % % NN cord-006870-f5w6fw6q 4319 7 of of IN cord-006870-f5w6fw6q 4319 8 patients patient NNS cord-006870-f5w6fw6q 4319 9 while while IN cord-006870-f5w6fw6q 4319 10 on on IN cord-006870-f5w6fw6q 4319 11 IVAT IVAT NNP cord-006870-f5w6fw6q 4319 12 . . . cord-006870-f5w6fw6q 4320 1 Unsuccessful unsuccessful JJ cord-006870-f5w6fw6q 4320 2 weaning weaning NN cord-006870-f5w6fw6q 4320 3 of of IN cord-006870-f5w6fw6q 4320 4 IVAT IVAT NNP cord-006870-f5w6fw6q 4320 5 was be VBD cord-006870-f5w6fw6q 4320 6 associated associate VBN cord-006870-f5w6fw6q 4320 7 with with IN cord-006870-f5w6fw6q 4320 8 a a DT cord-006870-f5w6fw6q 4320 9 higher high JJR cord-006870-f5w6fw6q 4320 10 depth depth NN cord-006870-f5w6fw6q 4320 11 of of IN cord-006870-f5w6fw6q 4320 12 SR SR NNP cord-006870-f5w6fw6q 4320 13 , , , cord-006870-f5w6fw6q 4320 14 which which WDT cord-006870-f5w6fw6q 4320 15 is be VBZ cord-006870-f5w6fw6q 4320 16 likely likely RB cord-006870-f5w6fw6q 4320 17 a a DT cord-006870-f5w6fw6q 4320 18 marker marker NN cord-006870-f5w6fw6q 4320 19 of of IN cord-006870-f5w6fw6q 4320 20 disease disease NN cord-006870-f5w6fw6q 4320 21 severity severity NN cord-006870-f5w6fw6q 4320 22 . . . cord-006870-f5w6fw6q 4321 1 Depth depth NN cord-006870-f5w6fw6q 4321 2 of of IN cord-006870-f5w6fw6q 4321 3 sedation sedation NN cord-006870-f5w6fw6q 4321 4 was be VBD cord-006870-f5w6fw6q 4321 5 not not RB cord-006870-f5w6fw6q 4321 6 associated associate VBN cord-006870-f5w6fw6q 4321 7 with with IN cord-006870-f5w6fw6q 4321 8 increased increase VBN cord-006870-f5w6fw6q 4321 9 risk risk NN cord-006870-f5w6fw6q 4321 10 of of IN cord-006870-f5w6fw6q 4321 11 infection infection NN cord-006870-f5w6fw6q 4321 12 , , , cord-006870-f5w6fw6q 4321 13 but but CC cord-006870-f5w6fw6q 4321 14 was be VBD cord-006870-f5w6fw6q 4321 15 associated associate VBN cord-006870-f5w6fw6q 4321 16 with with IN cord-006870-f5w6fw6q 4321 17 the the DT cord-006870-f5w6fw6q 4321 18 need need NN cord-006870-f5w6fw6q 4321 19 for for IN cord-006870-f5w6fw6q 4321 20 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4321 21 . . . cord-006870-f5w6fw6q 4322 1 Vasopressor vasopressor NN cord-006870-f5w6fw6q 4322 2 requirements requirement NNS cord-006870-f5w6fw6q 4322 3 are be VBP cord-006870-f5w6fw6q 4322 4 common common JJ cord-006870-f5w6fw6q 4322 5 . . . cord-006870-f5w6fw6q 4323 1 The the DT cord-006870-f5w6fw6q 4323 2 primary primary JJ cord-006870-f5w6fw6q 4323 3 objective objective NN cord-006870-f5w6fw6q 4323 4 of of IN cord-006870-f5w6fw6q 4323 5 this this DT cord-006870-f5w6fw6q 4323 6 study study NN cord-006870-f5w6fw6q 4323 7 was be VBD cord-006870-f5w6fw6q 4323 8 to to TO cord-006870-f5w6fw6q 4323 9 determine determine VB cord-006870-f5w6fw6q 4323 10 the the DT cord-006870-f5w6fw6q 4323 11 sensitivity sensitivity NN cord-006870-f5w6fw6q 4323 12 and and CC cord-006870-f5w6fw6q 4323 13 specificity specificity NN cord-006870-f5w6fw6q 4323 14 of of IN cord-006870-f5w6fw6q 4323 15 real real JJ cord-006870-f5w6fw6q 4323 16 - - HYPH cord-006870-f5w6fw6q 4323 17 time time NN cord-006870-f5w6fw6q 4323 18 Neuro Neuro NNP cord-006870-f5w6fw6q 4323 19 ICU ICU NNP cord-006870-f5w6fw6q 4323 20 nurse nurse NN cord-006870-f5w6fw6q 4323 21 interpretation interpretation NN cord-006870-f5w6fw6q 4323 22 of of IN cord-006870-f5w6fw6q 4323 23 quantitative quantitative JJ cord-006870-f5w6fw6q 4323 24 EEG EEG NNP cord-006870-f5w6fw6q 4323 25 ( ( -LRB- cord-006870-f5w6fw6q 4323 26 QEEG QEEG NNP cord-006870-f5w6fw6q 4323 27 ) ) -RRB- cord-006870-f5w6fw6q 4323 28 trends trend NNS cord-006870-f5w6fw6q 4323 29 in in IN cord-006870-f5w6fw6q 4323 30 the the DT cord-006870-f5w6fw6q 4323 31 identification identification NN cord-006870-f5w6fw6q 4323 32 of of IN cord-006870-f5w6fw6q 4323 33 recurrent recurrent JJ cord-006870-f5w6fw6q 4323 34 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 4323 35 electrographic electrographic JJ cord-006870-f5w6fw6q 4323 36 seizures seizure NNS cord-006870-f5w6fw6q 4323 37 in in IN cord-006870-f5w6fw6q 4323 38 adult adult NN cord-006870-f5w6fw6q 4323 39 patients patient NNS cord-006870-f5w6fw6q 4323 40 admitted admit VBN cord-006870-f5w6fw6q 4323 41 to to IN cord-006870-f5w6fw6q 4323 42 the the DT cord-006870-f5w6fw6q 4323 43 Neuro Neuro NNP cord-006870-f5w6fw6q 4323 44 ICU ICU NNP cord-006870-f5w6fw6q 4323 45 . . . cord-006870-f5w6fw6q 4324 1 Thirteen thirteen CD cord-006870-f5w6fw6q 4324 2 adult adult NN cord-006870-f5w6fw6q 4324 3 patients patient NNS cord-006870-f5w6fw6q 4324 4 admitted admit VBN cord-006870-f5w6fw6q 4324 5 to to IN cord-006870-f5w6fw6q 4324 6 the the DT cord-006870-f5w6fw6q 4324 7 Neuro Neuro NNP cord-006870-f5w6fw6q 4324 8 ICU ICU NNP cord-006870-f5w6fw6q 4324 9 that that WDT cord-006870-f5w6fw6q 4324 10 had have VBD cord-006870-f5w6fw6q 4324 11 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 4324 12 seizures seizure NNS cord-006870-f5w6fw6q 4324 13 on on IN cord-006870-f5w6fw6q 4324 14 continuous continuous JJ cord-006870-f5w6fw6q 4324 15 EEG EEG NNP cord-006870-f5w6fw6q 4324 16 ( ( -LRB- cord-006870-f5w6fw6q 4324 17 cEEG ceeg JJ cord-006870-f5w6fw6q 4324 18 ) ) -RRB- cord-006870-f5w6fw6q 4324 19 monitoring monitoring NN cord-006870-f5w6fw6q 4324 20 were be VBD cord-006870-f5w6fw6q 4324 21 included include VBN cord-006870-f5w6fw6q 4324 22 in in IN cord-006870-f5w6fw6q 4324 23 the the DT cord-006870-f5w6fw6q 4324 24 study study NN cord-006870-f5w6fw6q 4324 25 . . . cord-006870-f5w6fw6q 4325 1 Neuro Neuro NNP cord-006870-f5w6fw6q 4325 2 ICU ICU NNP cord-006870-f5w6fw6q 4325 3 nurses nurse NNS cord-006870-f5w6fw6q 4325 4 consented consent VBD cord-006870-f5w6fw6q 4325 5 for for IN cord-006870-f5w6fw6q 4325 6 their -PRON- PRP$ cord-006870-f5w6fw6q 4325 7 participation participation NN cord-006870-f5w6fw6q 4325 8 and and CC cord-006870-f5w6fw6q 4325 9 underwent undergo VBD cord-006870-f5w6fw6q 4325 10 a a DT cord-006870-f5w6fw6q 4325 11 brief brief JJ cord-006870-f5w6fw6q 4325 12 , , , cord-006870-f5w6fw6q 4325 13 standardized standardized JJ cord-006870-f5w6fw6q 4325 14 QEEG QEEG NNP cord-006870-f5w6fw6q 4325 15 training training NN cord-006870-f5w6fw6q 4325 16 session session NN cord-006870-f5w6fw6q 4325 17 . . . cord-006870-f5w6fw6q 4326 1 A a DT cord-006870-f5w6fw6q 4326 2 1-hour 1-hour CD cord-006870-f5w6fw6q 4326 3 QEEG QEEG NNP cord-006870-f5w6fw6q 4326 4 panel panel NN cord-006870-f5w6fw6q 4326 5 ( ( -LRB- cord-006870-f5w6fw6q 4326 6 rhythmicity rhythmicity NNP cord-006870-f5w6fw6q 4326 7 spectrogram spectrogram NN cord-006870-f5w6fw6q 4326 8 , , , cord-006870-f5w6fw6q 4326 9 left left JJ cord-006870-f5w6fw6q 4326 10 / / SYM cord-006870-f5w6fw6q 4326 11 right right NN cord-006870-f5w6fw6q 4326 12 and and CC cord-006870-f5w6fw6q 4326 13 amplitude amplitude NN cord-006870-f5w6fw6q 4326 14 - - HYPH cord-006870-f5w6fw6q 4326 15 integrated integrate VBN cord-006870-f5w6fw6q 4326 16 EEG EEG NNP cord-006870-f5w6fw6q 4326 17 , , , cord-006870-f5w6fw6q 4326 18 left left JJ cord-006870-f5w6fw6q 4326 19 / / SYM cord-006870-f5w6fw6q 4326 20 right right NN cord-006870-f5w6fw6q 4326 21 ) ) -RRB- cord-006870-f5w6fw6q 4326 22 printout printout NN cord-006870-f5w6fw6q 4326 23 containing contain VBG cord-006870-f5w6fw6q 4326 24 the the DT cord-006870-f5w6fw6q 4326 25 marked mark VBN cord-006870-f5w6fw6q 4326 26 sentinel sentinel NN cord-006870-f5w6fw6q 4326 27 seizure(s seizure(s NN cord-006870-f5w6fw6q 4326 28 ) ) -RRB- cord-006870-f5w6fw6q 4326 29 was be VBD cord-006870-f5w6fw6q 4326 30 displayed display VBN cord-006870-f5w6fw6q 4326 31 next next RB cord-006870-f5w6fw6q 4326 32 to to IN cord-006870-f5w6fw6q 4326 33 the the DT cord-006870-f5w6fw6q 4326 34 bedside bedside NN cord-006870-f5w6fw6q 4326 35 cEEG ceeg NN cord-006870-f5w6fw6q 4326 36 / / SYM cord-006870-f5w6fw6q 4326 37 QEEG QEEG NNP cord-006870-f5w6fw6q 4326 38 monitor monitor NN cord-006870-f5w6fw6q 4326 39 . . . cord-006870-f5w6fw6q 4327 1 At at IN cord-006870-f5w6fw6q 4327 2 one one CD cord-006870-f5w6fw6q 4327 3 - - HYPH cord-006870-f5w6fw6q 4327 4 hour hour NN cord-006870-f5w6fw6q 4327 5 intervals interval NNS cord-006870-f5w6fw6q 4327 6 , , , cord-006870-f5w6fw6q 4327 7 the the DT cord-006870-f5w6fw6q 4327 8 nurses nurse NNS cord-006870-f5w6fw6q 4327 9 logged log VBD cord-006870-f5w6fw6q 4327 10 the the DT cord-006870-f5w6fw6q 4327 11 number number NN cord-006870-f5w6fw6q 4327 12 of of IN cord-006870-f5w6fw6q 4327 13 seizures seizure NNS cord-006870-f5w6fw6q 4327 14 seen see VBN cord-006870-f5w6fw6q 4327 15 in in IN cord-006870-f5w6fw6q 4327 16 the the DT cord-006870-f5w6fw6q 4327 17 past past JJ cord-006870-f5w6fw6q 4327 18 hour hour NN cord-006870-f5w6fw6q 4327 19 based base VBN cord-006870-f5w6fw6q 4327 20 on on IN cord-006870-f5w6fw6q 4327 21 their -PRON- PRP$ cord-006870-f5w6fw6q 4327 22 QEEG QEEG NNP cord-006870-f5w6fw6q 4327 23 interpretation interpretation NN cord-006870-f5w6fw6q 4327 24 for for IN cord-006870-f5w6fw6q 4327 25 the the DT cord-006870-f5w6fw6q 4327 26 duration duration NN cord-006870-f5w6fw6q 4327 27 of of IN cord-006870-f5w6fw6q 4327 28 their -PRON- PRP$ cord-006870-f5w6fw6q 4327 29 shift shift NN cord-006870-f5w6fw6q 4327 30 . . . cord-006870-f5w6fw6q 4328 1 Their -PRON- PRP$ cord-006870-f5w6fw6q 4328 2 answers answer NNS cord-006870-f5w6fw6q 4328 3 were be VBD cord-006870-f5w6fw6q 4328 4 compared compare VBN cord-006870-f5w6fw6q 4328 5 with with IN cord-006870-f5w6fw6q 4328 6 the the DT cord-006870-f5w6fw6q 4328 7 gold gold NN cord-006870-f5w6fw6q 4328 8 standard standard NN cord-006870-f5w6fw6q 4328 9 of of IN cord-006870-f5w6fw6q 4328 10 neurophysiologist neurophysiologist JJ cord-006870-f5w6fw6q 4328 11 interpretation interpretation NN cord-006870-f5w6fw6q 4328 12 of of IN cord-006870-f5w6fw6q 4328 13 seizure seizure NN cord-006870-f5w6fw6q 4328 14 occurrence occurrence NN cord-006870-f5w6fw6q 4328 15 on on IN cord-006870-f5w6fw6q 4328 16 raw raw JJ cord-006870-f5w6fw6q 4328 17 EEG EEG NNP cord-006870-f5w6fw6q 4328 18 . . . cord-006870-f5w6fw6q 4329 1 A a DT cord-006870-f5w6fw6q 4329 2 total total NN cord-006870-f5w6fw6q 4329 3 of of IN cord-006870-f5w6fw6q 4329 4 120 120 CD cord-006870-f5w6fw6q 4329 5 hours hour NNS cord-006870-f5w6fw6q 4329 6 of of IN cord-006870-f5w6fw6q 4329 7 QEEG QEEG NNP cord-006870-f5w6fw6q 4329 8 data datum NNS cord-006870-f5w6fw6q 4329 9 was be VBD cord-006870-f5w6fw6q 4329 10 reviewed review VBN cord-006870-f5w6fw6q 4329 11 for for IN cord-006870-f5w6fw6q 4329 12 13 13 CD cord-006870-f5w6fw6q 4329 13 patients patient NNS cord-006870-f5w6fw6q 4329 14 . . . cord-006870-f5w6fw6q 4330 1 Average average JJ cord-006870-f5w6fw6q 4330 2 length length NN cord-006870-f5w6fw6q 4330 3 of of IN cord-006870-f5w6fw6q 4330 4 data datum NNS cord-006870-f5w6fw6q 4330 5 collection collection NN cord-006870-f5w6fw6q 4330 6 was be VBD cord-006870-f5w6fw6q 4330 7 9.5 9.5 CD cord-006870-f5w6fw6q 4330 8 hours hour NNS cord-006870-f5w6fw6q 4330 9 . . . cord-006870-f5w6fw6q 4331 1 For for IN cord-006870-f5w6fw6q 4331 2 the the DT cord-006870-f5w6fw6q 4331 3 Neuro Neuro NNP cord-006870-f5w6fw6q 4331 4 ICU ICU NNP cord-006870-f5w6fw6q 4331 5 nurses nurse NNS cord-006870-f5w6fw6q 4331 6 ' ' POS cord-006870-f5w6fw6q 4331 7 ability ability NN cord-006870-f5w6fw6q 4331 8 to to TO cord-006870-f5w6fw6q 4331 9 detect detect VB cord-006870-f5w6fw6q 4331 10 the the DT cord-006870-f5w6fw6q 4331 11 presence presence NN cord-006870-f5w6fw6q 4331 12 of of IN cord-006870-f5w6fw6q 4331 13 seizures seizure NNS cord-006870-f5w6fw6q 4331 14 on on IN cord-006870-f5w6fw6q 4331 15 real real JJ cord-006870-f5w6fw6q 4331 16 - - HYPH cord-006870-f5w6fw6q 4331 17 time time NN cord-006870-f5w6fw6q 4331 18 QEEG QEEG NNP cord-006870-f5w6fw6q 4332 1 the the DT cord-006870-f5w6fw6q 4332 2 sensitivity sensitivity NN cord-006870-f5w6fw6q 4332 3 was be VBD cord-006870-f5w6fw6q 4332 4 70.0 70.0 CD cord-006870-f5w6fw6q 4332 5 % % NN cord-006870-f5w6fw6q 4332 6 ( ( -LRB- cord-006870-f5w6fw6q 4332 7 95 95 CD cord-006870-f5w6fw6q 4332 8 % % NN cord-006870-f5w6fw6q 4332 9 CI CI NNP cord-006870-f5w6fw6q 4332 10 , , , cord-006870-f5w6fw6q 4332 11 34.8 34.8 CD cord-006870-f5w6fw6q 4332 12 - - HYPH cord-006870-f5w6fw6q 4332 13 93.3 93.3 CD cord-006870-f5w6fw6q 4332 14 % % NN cord-006870-f5w6fw6q 4332 15 ) ) -RRB- cord-006870-f5w6fw6q 4332 16 and and CC cord-006870-f5w6fw6q 4332 17 specificity specificity NN cord-006870-f5w6fw6q 4332 18 was be VBD cord-006870-f5w6fw6q 4332 19 90.0 90.0 CD cord-006870-f5w6fw6q 4332 20 % % NN cord-006870-f5w6fw6q 4332 21 ( ( -LRB- cord-006870-f5w6fw6q 4332 22 95 95 CD cord-006870-f5w6fw6q 4332 23 % % NN cord-006870-f5w6fw6q 4332 24 CI ci NN cord-006870-f5w6fw6q 4332 25 , , , cord-006870-f5w6fw6q 4332 26 82.8 82.8 CD cord-006870-f5w6fw6q 4332 27 - - HYPH cord-006870-f5w6fw6q 4332 28 94.9 94.9 CD cord-006870-f5w6fw6q 4332 29 % % NN cord-006870-f5w6fw6q 4332 30 ) ) -RRB- cord-006870-f5w6fw6q 4332 31 . . . cord-006870-f5w6fw6q 4333 1 The the DT cord-006870-f5w6fw6q 4333 2 positive positive JJ cord-006870-f5w6fw6q 4333 3 predictive predictive JJ cord-006870-f5w6fw6q 4333 4 value value NN cord-006870-f5w6fw6q 4333 5 for for IN cord-006870-f5w6fw6q 4333 6 seizure seizure NN cord-006870-f5w6fw6q 4333 7 detection detection NN cord-006870-f5w6fw6q 4333 8 was be VBD cord-006870-f5w6fw6q 4333 9 38.9 38.9 CD cord-006870-f5w6fw6q 4333 10 % % NN cord-006870-f5w6fw6q 4333 11 ( ( -LRB- cord-006870-f5w6fw6q 4333 12 95 95 CD cord-006870-f5w6fw6q 4333 13 % % NN cord-006870-f5w6fw6q 4333 14 CI ci NN cord-006870-f5w6fw6q 4333 15 , , , cord-006870-f5w6fw6q 4333 16 24.2 24.2 CD cord-006870-f5w6fw6q 4333 17 - - HYPH cord-006870-f5w6fw6q 4333 18 56.0 56.0 CD cord-006870-f5w6fw6q 4333 19 % % NN cord-006870-f5w6fw6q 4333 20 ) ) -RRB- cord-006870-f5w6fw6q 4333 21 and and CC cord-006870-f5w6fw6q 4333 22 the the DT cord-006870-f5w6fw6q 4333 23 negative negative JJ cord-006870-f5w6fw6q 4333 24 predictive predictive JJ cord-006870-f5w6fw6q 4333 25 value value NN cord-006870-f5w6fw6q 4333 26 was be VBD cord-006870-f5w6fw6q 4333 27 97.1 97.1 CD cord-006870-f5w6fw6q 4333 28 % % NN cord-006870-f5w6fw6q 4333 29 ( ( -LRB- cord-006870-f5w6fw6q 4333 30 95 95 CD cord-006870-f5w6fw6q 4333 31 % % NN cord-006870-f5w6fw6q 4333 32 CI CI NNP cord-006870-f5w6fw6q 4333 33 , , , cord-006870-f5w6fw6q 4333 34 92.7 92.7 CD cord-006870-f5w6fw6q 4333 35 - - HYPH cord-006870-f5w6fw6q 4333 36 98.8 98.8 CD cord-006870-f5w6fw6q 4333 37 % % NN cord-006870-f5w6fw6q 4333 38 ) ) -RRB- cord-006870-f5w6fw6q 4333 39 . . . cord-006870-f5w6fw6q 4334 1 The the DT cord-006870-f5w6fw6q 4334 2 false false JJ cord-006870-f5w6fw6q 4334 3 - - HYPH cord-006870-f5w6fw6q 4334 4 positive positive JJ cord-006870-f5w6fw6q 4334 5 rate rate NN cord-006870-f5w6fw6q 4334 6 was be VBD cord-006870-f5w6fw6q 4334 7 0.075 0.075 CD cord-006870-f5w6fw6q 4334 8 / / SYM cord-006870-f5w6fw6q 4334 9 hr hr NN cord-006870-f5w6fw6q 4334 10 . . . cord-006870-f5w6fw6q 4335 1 A a DT cord-006870-f5w6fw6q 4335 2 simplified simplified JJ cord-006870-f5w6fw6q 4335 3 panel panel NN cord-006870-f5w6fw6q 4335 4 of of IN cord-006870-f5w6fw6q 4335 5 QEEG QEEG NNP cord-006870-f5w6fw6q 4335 6 trends trend NNS cord-006870-f5w6fw6q 4335 7 can can MD cord-006870-f5w6fw6q 4335 8 be be VB cord-006870-f5w6fw6q 4335 9 used use VBN cord-006870-f5w6fw6q 4335 10 by by IN cord-006870-f5w6fw6q 4335 11 Neuro Neuro NNP cord-006870-f5w6fw6q 4335 12 ICU ICU NNP cord-006870-f5w6fw6q 4335 13 nurses nurse NNS cord-006870-f5w6fw6q 4335 14 to to TO cord-006870-f5w6fw6q 4335 15 screen screen VB cord-006870-f5w6fw6q 4335 16 for for IN cord-006870-f5w6fw6q 4335 17 recurrent recurrent JJ cord-006870-f5w6fw6q 4335 18 electrographic electrographic JJ cord-006870-f5w6fw6q 4335 19 seizures seizure NNS cord-006870-f5w6fw6q 4335 20 in in IN cord-006870-f5w6fw6q 4335 21 critically critically RB cord-006870-f5w6fw6q 4335 22 ill ill JJ cord-006870-f5w6fw6q 4335 23 patients patient NNS cord-006870-f5w6fw6q 4335 24 with with IN cord-006870-f5w6fw6q 4335 25 a a DT cord-006870-f5w6fw6q 4335 26 reasonable reasonable JJ cord-006870-f5w6fw6q 4335 27 sensitivity sensitivity NN cord-006870-f5w6fw6q 4335 28 , , , cord-006870-f5w6fw6q 4335 29 an an DT cord-006870-f5w6fw6q 4335 30 excellent excellent JJ cord-006870-f5w6fw6q 4335 31 specificity specificity NN cord-006870-f5w6fw6q 4335 32 and and CC cord-006870-f5w6fw6q 4335 33 a a DT cord-006870-f5w6fw6q 4335 34 very very RB cord-006870-f5w6fw6q 4335 35 low low JJ cord-006870-f5w6fw6q 4335 36 false false JJ cord-006870-f5w6fw6q 4335 37 - - HYPH cord-006870-f5w6fw6q 4335 38 positive positive JJ cord-006870-f5w6fw6q 4335 39 rate rate NN cord-006870-f5w6fw6q 4335 40 . . . cord-006870-f5w6fw6q 4336 1 This this DT cord-006870-f5w6fw6q 4336 2 may may MD cord-006870-f5w6fw6q 4336 3 facilitate facilitate VB cord-006870-f5w6fw6q 4336 4 earlier early JJR cord-006870-f5w6fw6q 4336 5 identification identification NN cord-006870-f5w6fw6q 4336 6 of of IN cord-006870-f5w6fw6q 4336 7 recurrent recurrent JJ cord-006870-f5w6fw6q 4336 8 electrographic electrographic JJ cord-006870-f5w6fw6q 4336 9 seizures seizure NNS cord-006870-f5w6fw6q 4336 10 by by IN cord-006870-f5w6fw6q 4336 11 notifying notify VBG cord-006870-f5w6fw6q 4336 12 the the DT cord-006870-f5w6fw6q 4336 13 neurophysiologist neurophysiologist NN cord-006870-f5w6fw6q 4336 14 who who WP cord-006870-f5w6fw6q 4336 15 is be VBZ cord-006870-f5w6fw6q 4336 16 not not RB cord-006870-f5w6fw6q 4336 17 present present JJ cord-006870-f5w6fw6q 4336 18 in in IN cord-006870-f5w6fw6q 4336 19 the the DT cord-006870-f5w6fw6q 4336 20 ICU ICU NNP cord-006870-f5w6fw6q 4336 21 and and CC cord-006870-f5w6fw6q 4336 22 not not RB cord-006870-f5w6fw6q 4336 23 able able JJ cord-006870-f5w6fw6q 4336 24 to to TO cord-006870-f5w6fw6q 4336 25 perform perform VB cord-006870-f5w6fw6q 4336 26 real real JJ cord-006870-f5w6fw6q 4336 27 - - HYPH cord-006870-f5w6fw6q 4336 28 time time NN cord-006870-f5w6fw6q 4336 29 cEEG ceeg JJ cord-006870-f5w6fw6q 4336 30 interpretation interpretation NN cord-006870-f5w6fw6q 4336 31 . . . cord-006870-f5w6fw6q 4337 1 Nonconvulsive nonconvulsive NN cord-006870-f5w6fw6q 4337 2 status status NN cord-006870-f5w6fw6q 4337 3 epilepticus epilepticus NN cord-006870-f5w6fw6q 4337 4 ( ( -LRB- cord-006870-f5w6fw6q 4337 5 NCSE NCSE NNP cord-006870-f5w6fw6q 4337 6 ) ) -RRB- cord-006870-f5w6fw6q 4337 7 is be VBZ cord-006870-f5w6fw6q 4337 8 an an DT cord-006870-f5w6fw6q 4337 9 indicator indicator NN cord-006870-f5w6fw6q 4337 10 of of IN cord-006870-f5w6fw6q 4337 11 poor poor JJ cord-006870-f5w6fw6q 4337 12 outcomes outcome NNS cord-006870-f5w6fw6q 4337 13 in in IN cord-006870-f5w6fw6q 4337 14 neurocritical neurocritical JJ cord-006870-f5w6fw6q 4337 15 care care NN cord-006870-f5w6fw6q 4337 16 settings setting NNS cord-006870-f5w6fw6q 4337 17 . . . cord-006870-f5w6fw6q 4338 1 However however RB cord-006870-f5w6fw6q 4338 2 , , , cord-006870-f5w6fw6q 4338 3 because because IN cord-006870-f5w6fw6q 4338 4 of of IN cord-006870-f5w6fw6q 4338 5 unfamiliarity unfamiliarity NN cord-006870-f5w6fw6q 4338 6 with with IN cord-006870-f5w6fw6q 4338 7 continuous continuous JJ cord-006870-f5w6fw6q 4338 8 electroencephalography electroencephalography NN cord-006870-f5w6fw6q 4338 9 monitoring monitoring NN cord-006870-f5w6fw6q 4338 10 ( ( -LRB- cord-006870-f5w6fw6q 4338 11 cEEG cEEG NNP cord-006870-f5w6fw6q 4338 12 ) ) -RRB- cord-006870-f5w6fw6q 4338 13 , , , cord-006870-f5w6fw6q 4338 14 the the DT cord-006870-f5w6fw6q 4338 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 4338 16 and and CC cord-006870-f5w6fw6q 4338 17 treatment treatment NN cord-006870-f5w6fw6q 4338 18 of of IN cord-006870-f5w6fw6q 4338 19 NCSE NCSE NNP cord-006870-f5w6fw6q 4338 20 remains remain VBZ cord-006870-f5w6fw6q 4338 21 challenging challenging JJ cord-006870-f5w6fw6q 4338 22 , , , cord-006870-f5w6fw6q 4338 23 and and CC cord-006870-f5w6fw6q 4338 24 its -PRON- PRP$ cord-006870-f5w6fw6q 4338 25 clinical clinical JJ cord-006870-f5w6fw6q 4338 26 impact impact NN cord-006870-f5w6fw6q 4338 27 and and CC cord-006870-f5w6fw6q 4338 28 prognostic prognostic JJ cord-006870-f5w6fw6q 4338 29 factors factor NNS cord-006870-f5w6fw6q 4338 30 have have VBP cord-006870-f5w6fw6q 4338 31 not not RB cord-006870-f5w6fw6q 4338 32 been be VBN cord-006870-f5w6fw6q 4338 33 sufficiently sufficiently RB cord-006870-f5w6fw6q 4338 34 reported report VBN cord-006870-f5w6fw6q 4338 35 in in IN cord-006870-f5w6fw6q 4338 36 Japan Japan NNP cord-006870-f5w6fw6q 4338 37 . . . cord-006870-f5w6fw6q 4339 1 We -PRON- PRP cord-006870-f5w6fw6q 4339 2 performed perform VBD cord-006870-f5w6fw6q 4339 3 cEEG ceeg RB cord-006870-f5w6fw6q 4339 4 for for IN cord-006870-f5w6fw6q 4339 5 188 188 CD cord-006870-f5w6fw6q 4339 6 adult adult NN cord-006870-f5w6fw6q 4339 7 patients patient NNS cord-006870-f5w6fw6q 4339 8 in in IN cord-006870-f5w6fw6q 4339 9 our -PRON- PRP$ cord-006870-f5w6fw6q 4339 10 neurocritical neurocritical JJ cord-006870-f5w6fw6q 4339 11 care care NN cord-006870-f5w6fw6q 4339 12 unit unit NN cord-006870-f5w6fw6q 4339 13 with with IN cord-006870-f5w6fw6q 4339 14 coma coma NN cord-006870-f5w6fw6q 4339 15 or or CC cord-006870-f5w6fw6q 4339 16 unexplained unexplained JJ cord-006870-f5w6fw6q 4339 17 altered alter VBN cord-006870-f5w6fw6q 4339 18 mental mental JJ cord-006870-f5w6fw6q 4339 19 status status NN cord-006870-f5w6fw6q 4339 20 from from IN cord-006870-f5w6fw6q 4339 21 April April NNP cord-006870-f5w6fw6q 4339 22 2013 2013 CD cord-006870-f5w6fw6q 4339 23 to to IN cord-006870-f5w6fw6q 4339 24 September September NNP cord-006870-f5w6fw6q 4339 25 2015 2015 CD cord-006870-f5w6fw6q 4339 26 . . . cord-006870-f5w6fw6q 4340 1 We -PRON- PRP cord-006870-f5w6fw6q 4340 2 reviewed review VBD cord-006870-f5w6fw6q 4340 3 all all DT cord-006870-f5w6fw6q 4340 4 cEEG ceeg JJ cord-006870-f5w6fw6q 4340 5 records record NNS cord-006870-f5w6fw6q 4340 6 according accord VBG cord-006870-f5w6fw6q 4340 7 to to IN cord-006870-f5w6fw6q 4340 8 the the DT cord-006870-f5w6fw6q 4340 9 American American NNP cord-006870-f5w6fw6q 4340 10 Clinical Clinical NNP cord-006870-f5w6fw6q 4340 11 Neurophysiology Neurophysiology NNP cord-006870-f5w6fw6q 4340 12 Society Society NNP cord-006870-f5w6fw6q 4340 13 's 's POS cord-006870-f5w6fw6q 4340 14 terminology terminology NN cord-006870-f5w6fw6q 4340 15 ( ( -LRB- cord-006870-f5w6fw6q 4340 16 2012 2012 CD cord-006870-f5w6fw6q 4340 17 version version NN cord-006870-f5w6fw6q 4340 18 ) ) -RRB- cord-006870-f5w6fw6q 4340 19 , , , cord-006870-f5w6fw6q 4340 20 and and CC cord-006870-f5w6fw6q 4340 21 diagnosed diagnose VBN cord-006870-f5w6fw6q 4340 22 patients patient NNS cord-006870-f5w6fw6q 4340 23 with with IN cord-006870-f5w6fw6q 4340 24 NCSE NCSE NNP cord-006870-f5w6fw6q 4340 25 when when WRB cord-006870-f5w6fw6q 4340 26 the the DT cord-006870-f5w6fw6q 4340 27 cEEG ceeg NN cord-006870-f5w6fw6q 4340 28 revealed reveal VBN cord-006870-f5w6fw6q 4340 29 spatiotemporally spatiotemporally RB cord-006870-f5w6fw6q 4340 30 evolving evolve VBG cord-006870-f5w6fw6q 4340 31 or or CC cord-006870-f5w6fw6q 4340 32 fluctuating fluctuate VBG cord-006870-f5w6fw6q 4340 33 periodic periodic JJ cord-006870-f5w6fw6q 4340 34 or or CC cord-006870-f5w6fw6q 4340 35 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4340 36 discharges discharge NNS cord-006870-f5w6fw6q 4340 37 and and CC cord-006870-f5w6fw6q 4340 38 after after IN cord-006870-f5w6fw6q 4340 39 considering consider VBG cord-006870-f5w6fw6q 4340 40 clinical clinical JJ cord-006870-f5w6fw6q 4340 41 information information NN cord-006870-f5w6fw6q 4340 42 based base VBN cord-006870-f5w6fw6q 4340 43 on on IN cord-006870-f5w6fw6q 4340 44 the the DT cord-006870-f5w6fw6q 4340 45 modified modify VBN cord-006870-f5w6fw6q 4340 46 Salzburg Salzburg NNP cord-006870-f5w6fw6q 4340 47 consensus consensus NN cord-006870-f5w6fw6q 4340 48 criteria criterion NNS cord-006870-f5w6fw6q 4340 49 . . . cord-006870-f5w6fw6q 4341 1 Patients patient NNS cord-006870-f5w6fw6q 4341 2 with with IN cord-006870-f5w6fw6q 4341 3 NCSE NCSE NNP cord-006870-f5w6fw6q 4341 4 were be VBD cord-006870-f5w6fw6q 4341 5 aggressively aggressively RB cord-006870-f5w6fw6q 4341 6 treated treat VBN cord-006870-f5w6fw6q 4341 7 with with IN cord-006870-f5w6fw6q 4341 8 benzodiazepines benzodiazepine NNS cord-006870-f5w6fw6q 4341 9 , , , cord-006870-f5w6fw6q 4341 10 fosphenytoin fosphenytoin NNP cord-006870-f5w6fw6q 4341 11 , , , cord-006870-f5w6fw6q 4341 12 and and CC cord-006870-f5w6fw6q 4341 13 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 4341 14 . . . cord-006870-f5w6fw6q 4342 1 They -PRON- PRP cord-006870-f5w6fw6q 4342 2 were be VBD cord-006870-f5w6fw6q 4342 3 divided divide VBN cord-006870-f5w6fw6q 4342 4 into into IN cord-006870-f5w6fw6q 4342 5 a a DT cord-006870-f5w6fw6q 4342 6 generalized generalized JJ cord-006870-f5w6fw6q 4342 7 convulsive convulsive JJ cord-006870-f5w6fw6q 4342 8 status status NN cord-006870-f5w6fw6q 4342 9 epilepticus epilepticus NN cord-006870-f5w6fw6q 4342 10 ( ( -LRB- cord-006870-f5w6fw6q 4342 11 GCSE GCSE NNP cord-006870-f5w6fw6q 4342 12 ) ) -RRB- cord-006870-f5w6fw6q 4342 13 group group NN cord-006870-f5w6fw6q 4342 14 and and CC cord-006870-f5w6fw6q 4342 15 a a DT cord-006870-f5w6fw6q 4342 16 non non JJ cord-006870-f5w6fw6q 4342 17 - - JJ cord-006870-f5w6fw6q 4342 18 GCSE gcse JJ cord-006870-f5w6fw6q 4342 19 group group NN cord-006870-f5w6fw6q 4342 20 . . . cord-006870-f5w6fw6q 4343 1 We -PRON- PRP cord-006870-f5w6fw6q 4343 2 compared compare VBD cord-006870-f5w6fw6q 4343 3 mortality mortality NN cord-006870-f5w6fw6q 4343 4 and and CC cord-006870-f5w6fw6q 4343 5 outcomes outcome NNS cord-006870-f5w6fw6q 4343 6 between between IN cord-006870-f5w6fw6q 4343 7 the the DT cord-006870-f5w6fw6q 4343 8 two two CD cord-006870-f5w6fw6q 4343 9 groups group NNS cord-006870-f5w6fw6q 4343 10 after after IN cord-006870-f5w6fw6q 4343 11 3 3 CD cord-006870-f5w6fw6q 4343 12 months month NNS cord-006870-f5w6fw6q 4343 13 using use VBG cord-006870-f5w6fw6q 4343 14 Fischer Fischer NNP cord-006870-f5w6fw6q 4343 15 's 's POS cord-006870-f5w6fw6q 4343 16 exact exact JJ cord-006870-f5w6fw6q 4343 17 test test NN cord-006870-f5w6fw6q 4343 18 . . . cord-006870-f5w6fw6q 4344 1 Outcomes outcome NNS cord-006870-f5w6fw6q 4344 2 were be VBD cord-006870-f5w6fw6q 4344 3 defined define VBN cord-006870-f5w6fw6q 4344 4 as as IN cord-006870-f5w6fw6q 4344 5 poor poor JJ cord-006870-f5w6fw6q 4344 6 when when WRB cord-006870-f5w6fw6q 4344 7 the the DT cord-006870-f5w6fw6q 4344 8 Glasgow Glasgow NNP cord-006870-f5w6fw6q 4344 9 Outcome Outcome NNP cord-006870-f5w6fw6q 4344 10 Scale Scale NNP cord-006870-f5w6fw6q 4344 11 score score NN cord-006870-f5w6fw6q 4344 12 was be VBD cord-006870-f5w6fw6q 4344 13 worse bad JJR cord-006870-f5w6fw6q 4344 14 at at IN cord-006870-f5w6fw6q 4344 15 the the DT cord-006870-f5w6fw6q 4344 16 3-month 3-month CD cord-006870-f5w6fw6q 4344 17 follow follow NN cord-006870-f5w6fw6q 4344 18 - - HYPH cord-006870-f5w6fw6q 4344 19 up up NN cord-006870-f5w6fw6q 4344 20 than than IN cord-006870-f5w6fw6q 4344 21 at at IN cord-006870-f5w6fw6q 4344 22 admission admission NN cord-006870-f5w6fw6q 4344 23 . . . cord-006870-f5w6fw6q 4345 1 We -PRON- PRP cord-006870-f5w6fw6q 4345 2 excluded exclude VBD cord-006870-f5w6fw6q 4345 3 15 15 CD cord-006870-f5w6fw6q 4345 4 cases case NNS cord-006870-f5w6fw6q 4345 5 undergoing undergo VBG cord-006870-f5w6fw6q 4345 6 supportive supportive JJ cord-006870-f5w6fw6q 4345 7 care care NN cord-006870-f5w6fw6q 4345 8 or or CC cord-006870-f5w6fw6q 4345 9 lacking lacking NN cord-006870-f5w6fw6q 4345 10 of of IN cord-006870-f5w6fw6q 4345 11 follow follow NN cord-006870-f5w6fw6q 4345 12 - - HYPH cord-006870-f5w6fw6q 4345 13 up up NN cord-006870-f5w6fw6q 4345 14 . . . cord-006870-f5w6fw6q 4346 1 Of of IN cord-006870-f5w6fw6q 4346 2 173 173 CD cord-006870-f5w6fw6q 4346 3 cases case NNS cord-006870-f5w6fw6q 4346 4 in in IN cord-006870-f5w6fw6q 4346 5 the the DT cord-006870-f5w6fw6q 4346 6 study study NN cord-006870-f5w6fw6q 4346 7 , , , cord-006870-f5w6fw6q 4346 8 61 61 CD cord-006870-f5w6fw6q 4346 9 cases case NNS cord-006870-f5w6fw6q 4346 10 were be VBD cord-006870-f5w6fw6q 4346 11 diagnosed diagnose VBN cord-006870-f5w6fw6q 4346 12 with with IN cord-006870-f5w6fw6q 4346 13 NCSE NCSE NNP cord-006870-f5w6fw6q 4346 14 , , , cord-006870-f5w6fw6q 4346 15 including include VBG cord-006870-f5w6fw6q 4346 16 18 18 CD cord-006870-f5w6fw6q 4346 17 cases case NNS cord-006870-f5w6fw6q 4346 18 with with IN cord-006870-f5w6fw6q 4346 19 accompanying accompany VBG cord-006870-f5w6fw6q 4346 20 GCSE GCSE NNP cord-006870-f5w6fw6q 4346 21 and and CC cord-006870-f5w6fw6q 4346 22 43 43 CD cord-006870-f5w6fw6q 4346 23 cases case NNS cord-006870-f5w6fw6q 4346 24 without without IN cord-006870-f5w6fw6q 4346 25 . . . cord-006870-f5w6fw6q 4347 1 Mortality mortality NN cord-006870-f5w6fw6q 4347 2 rates rate NNS cord-006870-f5w6fw6q 4347 3 at at IN cord-006870-f5w6fw6q 4347 4 the the DT cord-006870-f5w6fw6q 4347 5 3-month 3-month CD cord-006870-f5w6fw6q 4347 6 follow follow NN cord-006870-f5w6fw6q 4347 7 - - HYPH cord-006870-f5w6fw6q 4347 8 up up NN cord-006870-f5w6fw6q 4347 9 were be VBD cord-006870-f5w6fw6q 4347 10 significantly significantly RB cord-006870-f5w6fw6q 4347 11 higher high JJR cord-006870-f5w6fw6q 4347 12 in in IN cord-006870-f5w6fw6q 4347 13 the the DT cord-006870-f5w6fw6q 4347 14 non non JJ cord-006870-f5w6fw6q 4347 15 - - JJ cord-006870-f5w6fw6q 4347 16 GCSE gcse JJ cord-006870-f5w6fw6q 4347 17 group group NN cord-006870-f5w6fw6q 4347 18 than than IN cord-006870-f5w6fw6q 4347 19 the the DT cord-006870-f5w6fw6q 4347 20 GCSE GCSE NNP cord-006870-f5w6fw6q 4347 21 group group NN cord-006870-f5w6fw6q 4347 22 ( ( -LRB- cord-006870-f5w6fw6q 4347 23 19 19 CD cord-006870-f5w6fw6q 4347 24 % % NN cord-006870-f5w6fw6q 4347 25 vs. vs. IN cord-006870-f5w6fw6q 4347 26 0 0 CD cord-006870-f5w6fw6q 4347 27 % % NN cord-006870-f5w6fw6q 4347 28 , , , cord-006870-f5w6fw6q 4347 29 respectively respectively RB cord-006870-f5w6fw6q 4347 30 ; ; : cord-006870-f5w6fw6q 4347 31 p p NN cord-006870-f5w6fw6q 4347 32 = = SYM cord-006870-f5w6fw6q 4347 33 0.0492 0.0492 CD cord-006870-f5w6fw6q 4347 34 ) ) -RRB- cord-006870-f5w6fw6q 4347 35 . . . cord-006870-f5w6fw6q 4348 1 The the DT cord-006870-f5w6fw6q 4348 2 rate rate NN cord-006870-f5w6fw6q 4348 3 of of IN cord-006870-f5w6fw6q 4348 4 poor poor JJ cord-006870-f5w6fw6q 4348 5 outcomes outcome NNS cord-006870-f5w6fw6q 4348 6 was be VBD cord-006870-f5w6fw6q 4348 7 significantly significantly RB cord-006870-f5w6fw6q 4348 8 higher high JJR cord-006870-f5w6fw6q 4348 9 in in IN cord-006870-f5w6fw6q 4348 10 the the DT cord-006870-f5w6fw6q 4348 11 non non JJ cord-006870-f5w6fw6q 4348 12 - - JJ cord-006870-f5w6fw6q 4348 13 GCSE gcse JJ cord-006870-f5w6fw6q 4348 14 group group NN cord-006870-f5w6fw6q 4348 15 than than IN cord-006870-f5w6fw6q 4348 16 in in IN cord-006870-f5w6fw6q 4348 17 the the DT cord-006870-f5w6fw6q 4348 18 GCSE GCSE NNP cord-006870-f5w6fw6q 4348 19 group group NN cord-006870-f5w6fw6q 4348 20 ( ( -LRB- cord-006870-f5w6fw6q 4348 21 26 26 CD cord-006870-f5w6fw6q 4348 22 % % NN cord-006870-f5w6fw6q 4348 23 vs. vs. CC cord-006870-f5w6fw6q 4348 24 0 0 CD cord-006870-f5w6fw6q 4348 25 % % NN cord-006870-f5w6fw6q 4348 26 , , , cord-006870-f5w6fw6q 4348 27 respectively respectively RB cord-006870-f5w6fw6q 4348 28 ; ; : cord-006870-f5w6fw6q 4348 29 p p NN cord-006870-f5w6fw6q 4348 30 = = SYM cord-006870-f5w6fw6q 4348 31 0.0138 0.0138 CD cord-006870-f5w6fw6q 4348 32 ) ) -RRB- cord-006870-f5w6fw6q 4348 33 . . . cord-006870-f5w6fw6q 4349 1 This this DT cord-006870-f5w6fw6q 4349 2 study study NN cord-006870-f5w6fw6q 4349 3 suggests suggest VBZ cord-006870-f5w6fw6q 4349 4 that that IN cord-006870-f5w6fw6q 4349 5 the the DT cord-006870-f5w6fw6q 4349 6 absence absence NN cord-006870-f5w6fw6q 4349 7 of of IN cord-006870-f5w6fw6q 4349 8 GCSE GCSE NNP cord-006870-f5w6fw6q 4349 9 is be VBZ cord-006870-f5w6fw6q 4349 10 associated associate VBN cord-006870-f5w6fw6q 4349 11 with with IN cord-006870-f5w6fw6q 4349 12 increased increase VBN cord-006870-f5w6fw6q 4349 13 mortality mortality NN cord-006870-f5w6fw6q 4349 14 and and CC cord-006870-f5w6fw6q 4349 15 poor poor JJ cord-006870-f5w6fw6q 4349 16 outcomes outcome NNS cord-006870-f5w6fw6q 4349 17 among among IN cord-006870-f5w6fw6q 4349 18 NCSE NCSE NNP cord-006870-f5w6fw6q 4349 19 patients patient NNS cord-006870-f5w6fw6q 4349 20 . . . cord-006870-f5w6fw6q 4350 1 Limitations limitation NNS cord-006870-f5w6fw6q 4350 2 of of IN cord-006870-f5w6fw6q 4350 3 this this DT cord-006870-f5w6fw6q 4350 4 study study NN cord-006870-f5w6fw6q 4350 5 include include VBP cord-006870-f5w6fw6q 4350 6 its -PRON- PRP$ cord-006870-f5w6fw6q 4350 7 retrospective retrospective JJ cord-006870-f5w6fw6q 4350 8 design design NN cord-006870-f5w6fw6q 4350 9 and and CC cord-006870-f5w6fw6q 4350 10 small small JJ cord-006870-f5w6fw6q 4350 11 number number NN cord-006870-f5w6fw6q 4350 12 of of IN cord-006870-f5w6fw6q 4350 13 NCSE NCSE NNP cord-006870-f5w6fw6q 4350 14 patients patient NNS cord-006870-f5w6fw6q 4350 15 . . . cord-006870-f5w6fw6q 4351 1 Further further JJ cord-006870-f5w6fw6q 4351 2 studies study NNS cord-006870-f5w6fw6q 4351 3 are be VBP cord-006870-f5w6fw6q 4351 4 necessary necessary JJ cord-006870-f5w6fw6q 4351 5 to to TO cord-006870-f5w6fw6q 4351 6 identify identify VB cord-006870-f5w6fw6q 4351 7 additional additional JJ cord-006870-f5w6fw6q 4351 8 prognostic prognostic JJ cord-006870-f5w6fw6q 4351 9 factors factor NNS cord-006870-f5w6fw6q 4351 10 . . . cord-006870-f5w6fw6q 4352 1 Super super JJ cord-006870-f5w6fw6q 4352 2 - - JJ cord-006870-f5w6fw6q 4352 3 refractory refractory JJ cord-006870-f5w6fw6q 4352 4 status status NN cord-006870-f5w6fw6q 4352 5 epilepticus epilepticus NN cord-006870-f5w6fw6q 4352 6 ( ( -LRB- cord-006870-f5w6fw6q 4352 7 SRSE SRSE NNP cord-006870-f5w6fw6q 4352 8 ) ) -RRB- cord-006870-f5w6fw6q 4352 9 is be VBZ cord-006870-f5w6fw6q 4352 10 a a DT cord-006870-f5w6fw6q 4352 11 life life NN cord-006870-f5w6fw6q 4352 12 - - HYPH cord-006870-f5w6fw6q 4352 13 threatening threaten VBG cord-006870-f5w6fw6q 4352 14 condition condition NN cord-006870-f5w6fw6q 4352 15 in in IN cord-006870-f5w6fw6q 4352 16 which which WDT cord-006870-f5w6fw6q 4352 17 status status NN cord-006870-f5w6fw6q 4352 18 epilepticus epilepticus NN cord-006870-f5w6fw6q 4352 19 recurs recur VBZ cord-006870-f5w6fw6q 4352 20 or or CC cord-006870-f5w6fw6q 4352 21 continues continue VBZ cord-006870-f5w6fw6q 4352 22 for for IN cord-006870-f5w6fw6q 4352 23 over over IN cord-006870-f5w6fw6q 4352 24 24 24 CD cord-006870-f5w6fw6q 4352 25 hours hour NNS cord-006870-f5w6fw6q 4352 26 despite despite IN cord-006870-f5w6fw6q 4352 27 first- first- NN cord-006870-f5w6fw6q 4352 28 , , , cord-006870-f5w6fw6q 4352 29 second- second- JJ cord-006870-f5w6fw6q 4352 30 , , , cord-006870-f5w6fw6q 4352 31 and and CC cord-006870-f5w6fw6q 4352 32 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4352 33 third third JJ cord-006870-f5w6fw6q 4352 34 - - HYPH cord-006870-f5w6fw6q 4352 35 line line NN cord-006870-f5w6fw6q 4352 36 agent agent NN cord-006870-f5w6fw6q 4352 37 ( ( -LRB- cord-006870-f5w6fw6q 4352 38 TLA TLA NNP cord-006870-f5w6fw6q 4352 39 ) ) -RRB- cord-006870-f5w6fw6q 4352 40 medications medication NNS cord-006870-f5w6fw6q 4352 41 . . . cord-006870-f5w6fw6q 4353 1 No no DT cord-006870-f5w6fw6q 4353 2 treatments treatment NNS cord-006870-f5w6fw6q 4353 3 are be VBP cord-006870-f5w6fw6q 4353 4 currently currently RB cord-006870-f5w6fw6q 4353 5 approved approve VBN cord-006870-f5w6fw6q 4353 6 for for IN cord-006870-f5w6fw6q 4353 7 SRSE SRSE NNP cord-006870-f5w6fw6q 4353 8 . . . cord-006870-f5w6fw6q 4354 1 A a DT cord-006870-f5w6fw6q 4354 2 randomized randomized JJ cord-006870-f5w6fw6q 4354 3 , , , cord-006870-f5w6fw6q 4354 4 double double JJ cord-006870-f5w6fw6q 4354 5 - - HYPH cord-006870-f5w6fw6q 4354 6 blind blind JJ cord-006870-f5w6fw6q 4354 7 , , , cord-006870-f5w6fw6q 4354 8 multi multi JJ cord-006870-f5w6fw6q 4354 9 - - JJ cord-006870-f5w6fw6q 4354 10 center center JJ cord-006870-f5w6fw6q 4354 11 , , , cord-006870-f5w6fw6q 4354 12 placebo placebo NN cord-006870-f5w6fw6q 4354 13 - - HYPH cord-006870-f5w6fw6q 4354 14 controlled control VBN cord-006870-f5w6fw6q 4354 15 Phase Phase NNP cord-006870-f5w6fw6q 4354 16 3 3 CD cord-006870-f5w6fw6q 4354 17 trial trial NN cord-006870-f5w6fw6q 4354 18 evaluated evaluate VBD cord-006870-f5w6fw6q 4354 19 brexanolone brexanolone NNP cord-006870-f5w6fw6q 4354 20 ( ( -LRB- cord-006870-f5w6fw6q 4354 21 USAN USAN NNP cord-006870-f5w6fw6q 4354 22 ; ; : cord-006870-f5w6fw6q 4354 23 formerly formerly RB cord-006870-f5w6fw6q 4354 24 SAGE-547 SAGE-547 NNP cord-006870-f5w6fw6q 4354 25 Injection Injection NNP cord-006870-f5w6fw6q 4354 26 ) ) -RRB- cord-006870-f5w6fw6q 4354 27 , , , cord-006870-f5w6fw6q 4354 28 a a DT cord-006870-f5w6fw6q 4354 29 synaptic synaptic JJ cord-006870-f5w6fw6q 4354 30 and and CC cord-006870-f5w6fw6q 4354 31 extrasynaptic extrasynaptic JJ cord-006870-f5w6fw6q 4354 32 GABAA GABAA NNP cord-006870-f5w6fw6q 4354 33 receptor receptor NN cord-006870-f5w6fw6q 4354 34 positive positive JJ cord-006870-f5w6fw6q 4354 35 allosteric allosteric JJ cord-006870-f5w6fw6q 4354 36 modulator modulator NN cord-006870-f5w6fw6q 4354 37 as as IN cord-006870-f5w6fw6q 4354 38 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4354 39 therapy therapy NN cord-006870-f5w6fw6q 4354 40 for for IN cord-006870-f5w6fw6q 4354 41 SRSE SRSE NNP cord-006870-f5w6fw6q 4354 42 ( ( -LRB- cord-006870-f5w6fw6q 4354 43 NCT02477618 NCT02477618 NNP cord-006870-f5w6fw6q 4354 44 ; ; : cord-006870-f5w6fw6q 4354 45 " " `` cord-006870-f5w6fw6q 4354 46 STATUS STATUS NNP cord-006870-f5w6fw6q 4354 47 Trial Trial NNP cord-006870-f5w6fw6q 4354 48 " " '' cord-006870-f5w6fw6q 4354 49 ) ) -RRB- cord-006870-f5w6fw6q 4354 50 . . . cord-006870-f5w6fw6q 4355 1 Enrolled enrol VBN cord-006870-f5w6fw6q 4355 2 subjects subject NNS cord-006870-f5w6fw6q 4355 3 underwent undergo VBD cord-006870-f5w6fw6q 4355 4 a a DT cord-006870-f5w6fw6q 4355 5 qualifying qualify VBG cord-006870-f5w6fw6q 4355 6 TLA tla NN cord-006870-f5w6fw6q 4355 7 wean wean VB cord-006870-f5w6fw6q 4355 8 after after IN cord-006870-f5w6fw6q 4355 9 at at RB cord-006870-f5w6fw6q 4355 10 least least RBS cord-006870-f5w6fw6q 4355 11 24 24 CD cord-006870-f5w6fw6q 4355 12 hours hour NNS cord-006870-f5w6fw6q 4355 13 of of IN cord-006870-f5w6fw6q 4355 14 seizure seizure NN cord-006870-f5w6fw6q 4355 15 - - : cord-006870-f5w6fw6q 4355 16 or or CC cord-006870-f5w6fw6q 4355 17 burstsuppression burstsuppression NN cord-006870-f5w6fw6q 4355 18 . . . cord-006870-f5w6fw6q 4356 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4356 2 subjects subject NNS cord-006870-f5w6fw6q 4356 3 failing fail VBG cord-006870-f5w6fw6q 4356 4 the the DT cord-006870-f5w6fw6q 4356 5 qualifying qualifying NN cord-006870-f5w6fw6q 4356 6 wean wean NN cord-006870-f5w6fw6q 4356 7 were be VBD cord-006870-f5w6fw6q 4356 8 randomized randomized JJ cord-006870-f5w6fw6q 4356 9 1:1 1:1 CD cord-006870-f5w6fw6q 4356 10 to to IN cord-006870-f5w6fw6q 4356 11 a a DT cord-006870-f5w6fw6q 4356 12 blinded blinded JJ cord-006870-f5w6fw6q 4356 13 infusion infusion NN cord-006870-f5w6fw6q 4356 14 of of IN cord-006870-f5w6fw6q 4356 15 brexanolone brexanolone NNP cord-006870-f5w6fw6q 4356 16 or or CC cord-006870-f5w6fw6q 4356 17 placebo placebo NN cord-006870-f5w6fw6q 4356 18 as as IN cord-006870-f5w6fw6q 4356 19 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4356 20 therapy therapy NN cord-006870-f5w6fw6q 4356 21 following follow VBG cord-006870-f5w6fw6q 4356 22 resumption resumption NN cord-006870-f5w6fw6q 4356 23 of of IN cord-006870-f5w6fw6q 4356 24 one one CD cord-006870-f5w6fw6q 4356 25 or or CC cord-006870-f5w6fw6q 4356 26 more more JJR cord-006870-f5w6fw6q 4356 27 TLA TLA NNP cord-006870-f5w6fw6q 4356 28 infusions infusion NNS cord-006870-f5w6fw6q 4356 29 . . . cord-006870-f5w6fw6q 4357 1 Subjects subject NNS cord-006870-f5w6fw6q 4357 2 were be VBD cord-006870-f5w6fw6q 4357 3 administered administer VBN cord-006870-f5w6fw6q 4357 4 the the DT cord-006870-f5w6fw6q 4357 5 blinded blind VBN cord-006870-f5w6fw6q 4357 6 infusion infusion NN cord-006870-f5w6fw6q 4357 7 for for IN cord-006870-f5w6fw6q 4357 8 6 6 CD cord-006870-f5w6fw6q 4357 9 days day NNS cord-006870-f5w6fw6q 4357 10 , , , cord-006870-f5w6fw6q 4357 11 during during IN cord-006870-f5w6fw6q 4357 12 which which WDT cord-006870-f5w6fw6q 4357 13 attempts attempt NNS cord-006870-f5w6fw6q 4357 14 were be VBD cord-006870-f5w6fw6q 4357 15 made make VBN cord-006870-f5w6fw6q 4357 16 to to TO cord-006870-f5w6fw6q 4357 17 wean wean VB cord-006870-f5w6fw6q 4357 18 off off RP cord-006870-f5w6fw6q 4357 19 TLA TLA NNP cord-006870-f5w6fw6q 4357 20 infusions infusion NNS cord-006870-f5w6fw6q 4357 21 . . . cord-006870-f5w6fw6q 4358 1 Clinical Clinical NNP cord-006870-f5w6fw6q 4358 2 Standardization Standardization NNP cord-006870-f5w6fw6q 4358 3 Guidelines Guidelines NNPS cord-006870-f5w6fw6q 4358 4 ( ( -LRB- cord-006870-f5w6fw6q 4358 5 CSGs csg NNS cord-006870-f5w6fw6q 4358 6 ) ) -RRB- cord-006870-f5w6fw6q 4358 7 facilitated facilitate VBN cord-006870-f5w6fw6q 4358 8 standardization standardization NN cord-006870-f5w6fw6q 4358 9 across across IN cord-006870-f5w6fw6q 4358 10 sites site NNS cord-006870-f5w6fw6q 4358 11 by by IN cord-006870-f5w6fw6q 4358 12 outlining outline VBG cord-006870-f5w6fw6q 4358 13 EEG EEG NNP cord-006870-f5w6fw6q 4358 14 patterns pattern NNS cord-006870-f5w6fw6q 4358 15 for for IN cord-006870-f5w6fw6q 4358 16 which which WDT cord-006870-f5w6fw6q 4358 17 TLA tla NN cord-006870-f5w6fw6q 4358 18 weaning weaning NN cord-006870-f5w6fw6q 4358 19 should should MD cord-006870-f5w6fw6q 4358 20 be be VB cord-006870-f5w6fw6q 4358 21 continued continue VBN cord-006870-f5w6fw6q 4358 22 , , , cord-006870-f5w6fw6q 4358 23 paused pause VBD cord-006870-f5w6fw6q 4358 24 , , , cord-006870-f5w6fw6q 4358 25 or or CC cord-006870-f5w6fw6q 4358 26 discontinued discontinue VBN cord-006870-f5w6fw6q 4358 27 . . . cord-006870-f5w6fw6q 4359 1 An an DT cord-006870-f5w6fw6q 4359 2 on on IN cord-006870-f5w6fw6q 4359 3 - - HYPH cord-006870-f5w6fw6q 4359 4 call call NN cord-006870-f5w6fw6q 4359 5 Clinical Clinical NNP cord-006870-f5w6fw6q 4359 6 Standardization Standardization NNP cord-006870-f5w6fw6q 4359 7 Team Team NNP cord-006870-f5w6fw6q 4359 8 provided provide VBD cord-006870-f5w6fw6q 4359 9 real real JJ cord-006870-f5w6fw6q 4359 10 - - HYPH cord-006870-f5w6fw6q 4359 11 time time NN cord-006870-f5w6fw6q 4359 12 support support NN cord-006870-f5w6fw6q 4359 13 . . . cord-006870-f5w6fw6q 4360 1 Safety safety NN cord-006870-f5w6fw6q 4360 2 was be VBD cord-006870-f5w6fw6q 4360 3 assessed assess VBN cord-006870-f5w6fw6q 4360 4 via via IN cord-006870-f5w6fw6q 4360 5 adverse adverse JJ cord-006870-f5w6fw6q 4360 6 events event NNS cord-006870-f5w6fw6q 4360 7 , , , cord-006870-f5w6fw6q 4360 8 laboratory laboratory NN cord-006870-f5w6fw6q 4360 9 testing testing NN cord-006870-f5w6fw6q 4360 10 , , , cord-006870-f5w6fw6q 4360 11 vital vital JJ cord-006870-f5w6fw6q 4360 12 signs sign NNS cord-006870-f5w6fw6q 4360 13 , , , cord-006870-f5w6fw6q 4360 14 and and CC cord-006870-f5w6fw6q 4360 15 ECG ECG NNP cord-006870-f5w6fw6q 4360 16 parameters parameter NNS cord-006870-f5w6fw6q 4360 17 . . . cord-006870-f5w6fw6q 4361 1 The the DT cord-006870-f5w6fw6q 4361 2 primary primary JJ cord-006870-f5w6fw6q 4361 3 endpoint endpoint NN cord-006870-f5w6fw6q 4361 4 was be VBD cord-006870-f5w6fw6q 4361 5 defined define VBN cord-006870-f5w6fw6q 4361 6 as as IN cord-006870-f5w6fw6q 4361 7 successfully successfully RB cord-006870-f5w6fw6q 4361 8 Super super JJ cord-006870-f5w6fw6q 4361 9 - - JJ cord-006870-f5w6fw6q 4361 10 refractory refractory JJ cord-006870-f5w6fw6q 4361 11 status status NN cord-006870-f5w6fw6q 4361 12 epilepticus epilepticus NN cord-006870-f5w6fw6q 4361 13 ( ( -LRB- cord-006870-f5w6fw6q 4361 14 SRSE SRSE NNP cord-006870-f5w6fw6q 4361 15 ) ) -RRB- cord-006870-f5w6fw6q 4361 16 is be VBZ cord-006870-f5w6fw6q 4361 17 a a DT cord-006870-f5w6fw6q 4361 18 life life NN cord-006870-f5w6fw6q 4361 19 - - HYPH cord-006870-f5w6fw6q 4361 20 threatening threaten VBG cord-006870-f5w6fw6q 4361 21 neurological neurological JJ cord-006870-f5w6fw6q 4361 22 condition condition NN cord-006870-f5w6fw6q 4361 23 characterized characterize VBN cord-006870-f5w6fw6q 4361 24 by by IN cord-006870-f5w6fw6q 4361 25 status status NN cord-006870-f5w6fw6q 4361 26 epilepticus epilepticus NN cord-006870-f5w6fw6q 4361 27 persisting persist VBG cord-006870-f5w6fw6q 4361 28 over over IN cord-006870-f5w6fw6q 4361 29 24 24 CD cord-006870-f5w6fw6q 4361 30 hours hour NNS cord-006870-f5w6fw6q 4361 31 despite despite IN cord-006870-f5w6fw6q 4361 32 treatment treatment NN cord-006870-f5w6fw6q 4361 33 with with IN cord-006870-f5w6fw6q 4361 34 first- first- NN cord-006870-f5w6fw6q 4361 35 , , , cord-006870-f5w6fw6q 4361 36 second- second- JJ cord-006870-f5w6fw6q 4361 37 , , , cord-006870-f5w6fw6q 4361 38 and and CC cord-006870-f5w6fw6q 4361 39 third third JJ cord-006870-f5w6fw6q 4361 40 - - HYPH cord-006870-f5w6fw6q 4361 41 line line NN cord-006870-f5w6fw6q 4361 42 agents agent NNS cord-006870-f5w6fw6q 4361 43 ( ( -LRB- cord-006870-f5w6fw6q 4361 44 TLAs TLAs NNP cord-006870-f5w6fw6q 4361 45 ) ) -RRB- cord-006870-f5w6fw6q 4361 46 or or CC cord-006870-f5w6fw6q 4361 47 upon upon IN cord-006870-f5w6fw6q 4361 48 the the DT cord-006870-f5w6fw6q 4361 49 weaning weaning NN cord-006870-f5w6fw6q 4361 50 of of IN cord-006870-f5w6fw6q 4361 51 TLAs tla NNS cord-006870-f5w6fw6q 4361 52 . . . cord-006870-f5w6fw6q 4362 1 Currently currently RB cord-006870-f5w6fw6q 4362 2 , , , cord-006870-f5w6fw6q 4362 3 there there EX cord-006870-f5w6fw6q 4362 4 is be VBZ cord-006870-f5w6fw6q 4362 5 no no DT cord-006870-f5w6fw6q 4362 6 consensus consensus NN cord-006870-f5w6fw6q 4362 7 around around IN cord-006870-f5w6fw6q 4362 8 treatment treatment NN cord-006870-f5w6fw6q 4362 9 protocols protocol NNS cord-006870-f5w6fw6q 4362 10 for for IN cord-006870-f5w6fw6q 4362 11 SRSE SRSE NNP cord-006870-f5w6fw6q 4362 12 . . . cord-006870-f5w6fw6q 4363 1 This this DT cord-006870-f5w6fw6q 4363 2 study study NN cord-006870-f5w6fw6q 4363 3 aims aim VBZ cord-006870-f5w6fw6q 4363 4 to to TO cord-006870-f5w6fw6q 4363 5 describe describe VB cord-006870-f5w6fw6q 4363 6 SRSE SRSE NNP cord-006870-f5w6fw6q 4363 7 treatment treatment NN cord-006870-f5w6fw6q 4363 8 patterns pattern NNS cord-006870-f5w6fw6q 4363 9 and and CC cord-006870-f5w6fw6q 4363 10 related related JJ cord-006870-f5w6fw6q 4363 11 outcomes outcome NNS cord-006870-f5w6fw6q 4363 12 in in IN cord-006870-f5w6fw6q 4363 13 a a DT cord-006870-f5w6fw6q 4363 14 US US NNP cord-006870-f5w6fw6q 4363 15 population population NN cord-006870-f5w6fw6q 4363 16 . . . cord-006870-f5w6fw6q 4364 1 We -PRON- PRP cord-006870-f5w6fw6q 4364 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 4364 3 identified identify VBD cord-006870-f5w6fw6q 4364 4 SRSE SRSE NNP cord-006870-f5w6fw6q 4364 5 cases case NNS cord-006870-f5w6fw6q 4364 6 in in IN cord-006870-f5w6fw6q 4364 7 Cerner Cerner NNP cord-006870-f5w6fw6q 4364 8 HealthFacts HealthFacts NNP cord-006870-f5w6fw6q 4364 9 ® ® NNP cord-006870-f5w6fw6q 4364 10 , , , cord-006870-f5w6fw6q 4364 11 a a DT cord-006870-f5w6fw6q 4364 12 large large JJ cord-006870-f5w6fw6q 4364 13 , , , cord-006870-f5w6fw6q 4364 14 de de NN cord-006870-f5w6fw6q 4364 15 - - VBN cord-006870-f5w6fw6q 4364 16 identified identify VBN cord-006870-f5w6fw6q 4364 17 , , , cord-006870-f5w6fw6q 4364 18 US US NNP cord-006870-f5w6fw6q 4364 19 electronic electronic JJ cord-006870-f5w6fw6q 4364 20 health health NN cord-006870-f5w6fw6q 4364 21 record record NN cord-006870-f5w6fw6q 4364 22 database database NN cord-006870-f5w6fw6q 4364 23 , , , cord-006870-f5w6fw6q 4364 24 using use VBG cord-006870-f5w6fw6q 4364 25 records record NNS cord-006870-f5w6fw6q 4364 26 from from IN cord-006870-f5w6fw6q 4364 27 2000 2000 CD cord-006870-f5w6fw6q 4364 28 - - SYM cord-006870-f5w6fw6q 4364 29 2015 2015 CD cord-006870-f5w6fw6q 4364 30 . . . cord-006870-f5w6fw6q 4365 1 Cases case NNS cord-006870-f5w6fw6q 4365 2 were be VBD cord-006870-f5w6fw6q 4365 3 classified classify VBN cord-006870-f5w6fw6q 4365 4 as as IN cord-006870-f5w6fw6q 4365 5 SRSE SRSE NNP cord-006870-f5w6fw6q 4365 6 using use VBG cord-006870-f5w6fw6q 4365 7 a a DT cord-006870-f5w6fw6q 4365 8 modified modify VBN cord-006870-f5w6fw6q 4365 9 version version NN cord-006870-f5w6fw6q 4365 10 of of IN cord-006870-f5w6fw6q 4365 11 a a DT cord-006870-f5w6fw6q 4365 12 previously previously RB cord-006870-f5w6fw6q 4365 13 published publish VBN cord-006870-f5w6fw6q 4365 14 algorithm algorithm NN cord-006870-f5w6fw6q 4365 15 using use VBG cord-006870-f5w6fw6q 4365 16 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 4365 17 and and CC cord-006870-f5w6fw6q 4365 18 procedure procedure NN cord-006870-f5w6fw6q 4365 19 coding coding NN cord-006870-f5w6fw6q 4365 20 for for IN cord-006870-f5w6fw6q 4365 21 status status NN cord-006870-f5w6fw6q 4365 22 epilepticus epilepticus NN cord-006870-f5w6fw6q 4365 23 ( ( -LRB- cord-006870-f5w6fw6q 4365 24 345.00 345.00 CD cord-006870-f5w6fw6q 4365 25 , , , cord-006870-f5w6fw6q 4365 26 345.01 345.01 CD cord-006870-f5w6fw6q 4365 27 , , , cord-006870-f5w6fw6q 4365 28 345.1x 345.1x CD cord-006870-f5w6fw6q 4365 29 , , , cord-006870-f5w6fw6q 4365 30 345.3 345.3 CD cord-006870-f5w6fw6q 4365 31 , , , cord-006870-f5w6fw6q 4365 32 345.41 345.41 CD cord-006870-f5w6fw6q 4365 33 , , , cord-006870-f5w6fw6q 4365 34 345.51 345.51 CD cord-006870-f5w6fw6q 4365 35 , , , cord-006870-f5w6fw6q 4365 36 and and CC cord-006870-f5w6fw6q 4365 37 345.81 345.81 CD cord-006870-f5w6fw6q 4365 38 ) ) -RRB- cord-006870-f5w6fw6q 4365 39 , , , cord-006870-f5w6fw6q 4365 40 ventilator ventilator NN cord-006870-f5w6fw6q 4365 41 support support NN cord-006870-f5w6fw6q 4365 42 , , , cord-006870-f5w6fw6q 4365 43 pharmacotherapies pharmacotherapie NNS cord-006870-f5w6fw6q 4365 44 . . . cord-006870-f5w6fw6q 4366 1 Descriptive descriptive JJ cord-006870-f5w6fw6q 4366 2 and and CC cord-006870-f5w6fw6q 4366 3 univariate univariate JJ cord-006870-f5w6fw6q 4366 4 statistics statistic NNS cord-006870-f5w6fw6q 4366 5 were be VBD cord-006870-f5w6fw6q 4366 6 used use VBN cord-006870-f5w6fw6q 4366 7 to to TO cord-006870-f5w6fw6q 4366 8 evaluate evaluate VB cord-006870-f5w6fw6q 4366 9 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4366 10 treatment treatment NN cord-006870-f5w6fw6q 4366 11 , , , cord-006870-f5w6fw6q 4366 12 anti anti JJ cord-006870-f5w6fw6q 4366 13 - - JJ cord-006870-f5w6fw6q 4366 14 epileptic epileptic JJ cord-006870-f5w6fw6q 4366 15 medications medication NNS cord-006870-f5w6fw6q 4366 16 , , , cord-006870-f5w6fw6q 4366 17 and and CC cord-006870-f5w6fw6q 4366 18 the the DT cord-006870-f5w6fw6q 4366 19 association association NN cord-006870-f5w6fw6q 4366 20 between between IN cord-006870-f5w6fw6q 4366 21 Glasgow Glasgow NNP cord-006870-f5w6fw6q 4366 22 Coma Coma NNP cord-006870-f5w6fw6q 4366 23 Score Score NNP cord-006870-f5w6fw6q 4366 24 ( ( -LRB- cord-006870-f5w6fw6q 4366 25 GCS GCS NNP cord-006870-f5w6fw6q 4366 26 ) ) -RRB- cord-006870-f5w6fw6q 4366 27 and and CC cord-006870-f5w6fw6q 4366 28 mortality mortality NN cord-006870-f5w6fw6q 4366 29 . . . cord-006870-f5w6fw6q 4367 1 Using use VBG cord-006870-f5w6fw6q 4367 2 our -PRON- PRP$ cord-006870-f5w6fw6q 4367 3 algorithm algorithm NN cord-006870-f5w6fw6q 4367 4 , , , cord-006870-f5w6fw6q 4367 5 1153 1153 CD cord-006870-f5w6fw6q 4367 6 SRSE SRSE NNP cord-006870-f5w6fw6q 4367 7 cases case NNS cord-006870-f5w6fw6q 4367 8 ( ( -LRB- cord-006870-f5w6fw6q 4367 9 1137 1137 CD cord-006870-f5w6fw6q 4367 10 patients patient NNS cord-006870-f5w6fw6q 4367 11 ) ) -RRB- cord-006870-f5w6fw6q 4367 12 were be VBD cord-006870-f5w6fw6q 4367 13 classified classify VBN cord-006870-f5w6fw6q 4367 14 . . . cord-006870-f5w6fw6q 4368 1 Multiple multiple JJ cord-006870-f5w6fw6q 4368 2 TLAs tla NNS cord-006870-f5w6fw6q 4368 3 were be VBD cord-006870-f5w6fw6q 4368 4 received receive VBN cord-006870-f5w6fw6q 4368 5 in in IN cord-006870-f5w6fw6q 4368 6 89 89 CD cord-006870-f5w6fw6q 4368 7 % % NN cord-006870-f5w6fw6q 4368 8 of of IN cord-006870-f5w6fw6q 4368 9 cases case NNS cord-006870-f5w6fw6q 4368 10 , , , cord-006870-f5w6fw6q 4368 11 and and CC cord-006870-f5w6fw6q 4368 12 in in IN cord-006870-f5w6fw6q 4368 13 37 37 CD cord-006870-f5w6fw6q 4368 14 % % NN cord-006870-f5w6fw6q 4368 15 , , , cord-006870-f5w6fw6q 4368 16 > > XX cord-006870-f5w6fw6q 4368 17 2 2 CD cord-006870-f5w6fw6q 4368 18 concurrent concurrent JJ cord-006870-f5w6fw6q 4368 19 TLAs tla NNS cord-006870-f5w6fw6q 4368 20 were be VBD cord-006870-f5w6fw6q 4368 21 received receive VBN cord-006870-f5w6fw6q 4368 22 . . . cord-006870-f5w6fw6q 4369 1 The the DT cord-006870-f5w6fw6q 4369 2 first first JJ cord-006870-f5w6fw6q 4369 3 post post JJ cord-006870-f5w6fw6q 4369 4 - - JJ cord-006870-f5w6fw6q 4369 5 admission admission JJ cord-006870-f5w6fw6q 4369 6 TLAs tla NNS cord-006870-f5w6fw6q 4369 7 were be VBD cord-006870-f5w6fw6q 4369 8 propofol propofol VBN cord-006870-f5w6fw6q 4369 9 , , , cord-006870-f5w6fw6q 4369 10 lorazepam lorazepam NN cord-006870-f5w6fw6q 4369 11 and and CC cord-006870-f5w6fw6q 4369 12 midazolam midazolam NN cord-006870-f5w6fw6q 4369 13 , , , cord-006870-f5w6fw6q 4369 14 respectively respectively RB cord-006870-f5w6fw6q 4369 15 , , , cord-006870-f5w6fw6q 4369 16 in in IN cord-006870-f5w6fw6q 4369 17 38 38 CD cord-006870-f5w6fw6q 4369 18 % % NN cord-006870-f5w6fw6q 4369 19 , , , cord-006870-f5w6fw6q 4369 20 38 38 CD cord-006870-f5w6fw6q 4369 21 % % NN cord-006870-f5w6fw6q 4369 22 and and CC cord-006870-f5w6fw6q 4369 23 18 18 CD cord-006870-f5w6fw6q 4369 24 % % NN cord-006870-f5w6fw6q 4369 25 of of IN cord-006870-f5w6fw6q 4369 26 cases case NNS cord-006870-f5w6fw6q 4369 27 . . . cord-006870-f5w6fw6q 4370 1 Median median JJ cord-006870-f5w6fw6q 4370 2 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4370 3 duration duration NN cord-006870-f5w6fw6q 4370 4 was be VBD cord-006870-f5w6fw6q 4370 5 9.5 9.5 CD cord-006870-f5w6fw6q 4370 6 days day NNS cord-006870-f5w6fw6q 4370 7 . . . cord-006870-f5w6fw6q 4371 1 Mortality mortality NN cord-006870-f5w6fw6q 4371 2 was be VBD cord-006870-f5w6fw6q 4371 3 higher high JJR cord-006870-f5w6fw6q 4371 4 in in IN cord-006870-f5w6fw6q 4371 5 -8 -8 NNP cord-006870-f5w6fw6q 4371 6 ( ( -LRB- cord-006870-f5w6fw6q 4371 7 3.1 3.1 CD cord-006870-f5w6fw6q 4371 8 vs. vs. IN cord-006870-f5w6fw6q 4371 9 1.6 1.6 CD cord-006870-f5w6fw6q 4371 10 days day NNS cord-006870-f5w6fw6q 4371 11 ; ; : cord-006870-f5w6fw6q 4371 12 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4371 13 ) ) -RRB- cord-006870-f5w6fw6q 4371 14 . . . cord-006870-f5w6fw6q 4372 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4372 2 patients patient NNS cord-006870-f5w6fw6q 4372 3 identified identify VBN cord-006870-f5w6fw6q 4372 4 in in IN cord-006870-f5w6fw6q 4372 5 our -PRON- PRP$ cord-006870-f5w6fw6q 4372 6 analysis analysis NN cord-006870-f5w6fw6q 4372 7 underwent undergo VBD cord-006870-f5w6fw6q 4372 8 variable variable JJ cord-006870-f5w6fw6q 4372 9 treatment treatment NN cord-006870-f5w6fw6q 4372 10 patterns pattern NNS cord-006870-f5w6fw6q 4372 11 , , , cord-006870-f5w6fw6q 4372 12 reflecting reflect VBG cord-006870-f5w6fw6q 4372 13 lack lack NN cord-006870-f5w6fw6q 4372 14 of of IN cord-006870-f5w6fw6q 4372 15 co co NN cord-006870-f5w6fw6q 4372 16 days day NNS cord-006870-f5w6fw6q 4372 17 of of IN cord-006870-f5w6fw6q 4372 18 TLA TLA NNP cord-006870-f5w6fw6q 4372 19 treatment treatment NN cord-006870-f5w6fw6q 4372 20 . . . cord-006870-f5w6fw6q 4373 1 Nonconvulsive Nonconvulsive NNP cord-006870-f5w6fw6q 4373 2 seizures seizure NNS cord-006870-f5w6fw6q 4373 3 ( ( -LRB- cord-006870-f5w6fw6q 4373 4 NCS NCS NNP cord-006870-f5w6fw6q 4373 5 ) ) -RRB- cord-006870-f5w6fw6q 4373 6 and and CC cord-006870-f5w6fw6q 4373 7 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 4373 8 status status NN cord-006870-f5w6fw6q 4373 9 epilepticus epilepticus NN cord-006870-f5w6fw6q 4373 10 ( ( -LRB- cord-006870-f5w6fw6q 4373 11 NCSE NCSE NNP cord-006870-f5w6fw6q 4373 12 ) ) -RRB- cord-006870-f5w6fw6q 4373 13 occur occur VBP cord-006870-f5w6fw6q 4373 14 in in IN cord-006870-f5w6fw6q 4373 15 approximately approximately RB cord-006870-f5w6fw6q 4373 16 20 20 CD cord-006870-f5w6fw6q 4373 17 % % NN cord-006870-f5w6fw6q 4373 18 of of IN cord-006870-f5w6fw6q 4373 19 neurologically neurologically RB cord-006870-f5w6fw6q 4373 20 critically critically RB cord-006870-f5w6fw6q 4373 21 ill ill JJ cord-006870-f5w6fw6q 4373 22 patients patient NNS cord-006870-f5w6fw6q 4373 23 . . . cord-006870-f5w6fw6q 4374 1 The the DT cord-006870-f5w6fw6q 4374 2 most most RBS cord-006870-f5w6fw6q 4374 3 effective effective JJ cord-006870-f5w6fw6q 4374 4 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 4374 5 drug drug NN cord-006870-f5w6fw6q 4374 6 ( ( -LRB- cord-006870-f5w6fw6q 4374 7 AED AED NNP cord-006870-f5w6fw6q 4374 8 ) ) -RRB- cord-006870-f5w6fw6q 4374 9 regimen regimen NN cord-006870-f5w6fw6q 4374 10 to to TO cord-006870-f5w6fw6q 4374 11 treat treat VB cord-006870-f5w6fw6q 4374 12 NCS NCS NNP cord-006870-f5w6fw6q 4374 13 and and CC cord-006870-f5w6fw6q 4374 14 NCSE NCSE NNP cord-006870-f5w6fw6q 4374 15 is be VBZ cord-006870-f5w6fw6q 4374 16 unknown unknown JJ cord-006870-f5w6fw6q 4374 17 . . . cord-006870-f5w6fw6q 4375 1 This this DT cord-006870-f5w6fw6q 4375 2 study study NN cord-006870-f5w6fw6q 4375 3 was be VBD cord-006870-f5w6fw6q 4375 4 designed design VBN cord-006870-f5w6fw6q 4375 5 to to TO cord-006870-f5w6fw6q 4375 6 determine determine VB cord-006870-f5w6fw6q 4375 7 the the DT cord-006870-f5w6fw6q 4375 8 efficacy efficacy NN cord-006870-f5w6fw6q 4375 9 of of IN cord-006870-f5w6fw6q 4375 10 add add VB cord-006870-f5w6fw6q 4375 11 - - HYPH cord-006870-f5w6fw6q 4375 12 on on RP cord-006870-f5w6fw6q 4375 13 clobazam clobazam NNP cord-006870-f5w6fw6q 4375 14 , , , cord-006870-f5w6fw6q 4375 15 a a DT cord-006870-f5w6fw6q 4375 16 unique unique JJ cord-006870-f5w6fw6q 4375 17 1,5-benzodiazepine 1,5-benzodiazepine NN cord-006870-f5w6fw6q 4375 18 with with IN cord-006870-f5w6fw6q 4375 19 favorable favorable JJ cord-006870-f5w6fw6q 4375 20 pharmacokinetic pharmacokinetic JJ cord-006870-f5w6fw6q 4375 21 properties property NNS cord-006870-f5w6fw6q 4375 22 , , , cord-006870-f5w6fw6q 4375 23 in in IN cord-006870-f5w6fw6q 4375 24 the the DT cord-006870-f5w6fw6q 4375 25 treatment treatment NN cord-006870-f5w6fw6q 4375 26 of of IN cord-006870-f5w6fw6q 4375 27 NCS NCS NNP cord-006870-f5w6fw6q 4375 28 and and CC cord-006870-f5w6fw6q 4375 29 NCSE NCSE NNP cord-006870-f5w6fw6q 4375 30 . . . cord-006870-f5w6fw6q 4376 1 A a DT cord-006870-f5w6fw6q 4376 2 retrospective retrospective JJ cord-006870-f5w6fw6q 4376 3 chart chart NN cord-006870-f5w6fw6q 4376 4 review review NN cord-006870-f5w6fw6q 4376 5 was be VBD cord-006870-f5w6fw6q 4376 6 performed perform VBN cord-006870-f5w6fw6q 4376 7 on on IN cord-006870-f5w6fw6q 4376 8 17 17 CD cord-006870-f5w6fw6q 4376 9 adult adult NN cord-006870-f5w6fw6q 4376 10 patients patient NNS cord-006870-f5w6fw6q 4376 11 who who WP cord-006870-f5w6fw6q 4376 12 were be VBD cord-006870-f5w6fw6q 4376 13 admitted admit VBN cord-006870-f5w6fw6q 4376 14 to to IN cord-006870-f5w6fw6q 4376 15 the the DT cord-006870-f5w6fw6q 4376 16 neurological neurological JJ cord-006870-f5w6fw6q 4376 17 intensive intensive JJ cord-006870-f5w6fw6q 4376 18 care care NN cord-006870-f5w6fw6q 4376 19 unit unit NN cord-006870-f5w6fw6q 4376 20 between between IN cord-006870-f5w6fw6q 4376 21 January January NNP cord-006870-f5w6fw6q 4376 22 1 1 CD cord-006870-f5w6fw6q 4376 23 , , , cord-006870-f5w6fw6q 4376 24 2013 2013 CD cord-006870-f5w6fw6q 4376 25 and and CC cord-006870-f5w6fw6q 4376 26 June June NNP cord-006870-f5w6fw6q 4376 27 1 1 CD cord-006870-f5w6fw6q 4376 28 , , , cord-006870-f5w6fw6q 4376 29 2017 2017 CD cord-006870-f5w6fw6q 4376 30 , , , cord-006870-f5w6fw6q 4376 31 were be VBD cord-006870-f5w6fw6q 4376 32 diagnosed diagnose VBN cord-006870-f5w6fw6q 4376 33 with with IN cord-006870-f5w6fw6q 4376 34 NCS NCS NNP cord-006870-f5w6fw6q 4376 35 or or CC cord-006870-f5w6fw6q 4376 36 NCSE NCSE NNP cord-006870-f5w6fw6q 4376 37 by by IN cord-006870-f5w6fw6q 4376 38 continuous continuous JJ cord-006870-f5w6fw6q 4376 39 EEG EEG NNP cord-006870-f5w6fw6q 4376 40 monitoring monitoring NN cord-006870-f5w6fw6q 4376 41 and and CC cord-006870-f5w6fw6q 4376 42 received receive VBD cord-006870-f5w6fw6q 4376 43 clobazam clobazam NNP cord-006870-f5w6fw6q 4376 44 as as IN cord-006870-f5w6fw6q 4376 45 add add NN cord-006870-f5w6fw6q 4376 46 - - HYPH cord-006870-f5w6fw6q 4376 47 on on RP cord-006870-f5w6fw6q 4376 48 therapy therapy NN cord-006870-f5w6fw6q 4376 49 . . . cord-006870-f5w6fw6q 4377 1 The the DT cord-006870-f5w6fw6q 4377 2 primary primary JJ cord-006870-f5w6fw6q 4377 3 efficacy efficacy NN cord-006870-f5w6fw6q 4377 4 endpoint endpoint NN cord-006870-f5w6fw6q 4377 5 was be VBD cord-006870-f5w6fw6q 4377 6 defined define VBN cord-006870-f5w6fw6q 4377 7 as as IN cord-006870-f5w6fw6q 4377 8 clobazam clobazam NNP cord-006870-f5w6fw6q 4377 9 being be VBG cord-006870-f5w6fw6q 4377 10 the the DT cord-006870-f5w6fw6q 4377 11 last last JJ cord-006870-f5w6fw6q 4377 12 AED AED NNP cord-006870-f5w6fw6q 4377 13 added add VBD cord-006870-f5w6fw6q 4377 14 before before IN cord-006870-f5w6fw6q 4377 15 NCS NCS NNP cord-006870-f5w6fw6q 4377 16 / / SYM cord-006870-f5w6fw6q 4377 17 NCSE NCSE NNP cord-006870-f5w6fw6q 4377 18 cessation cessation NN cord-006870-f5w6fw6q 4377 19 , , , cord-006870-f5w6fw6q 4377 20 regardless regardless RB cord-006870-f5w6fw6q 4377 21 of of IN cord-006870-f5w6fw6q 4377 22 latency latency NN cord-006870-f5w6fw6q 4377 23 between between IN cord-006870-f5w6fw6q 4377 24 dosing dosing NN cord-006870-f5w6fw6q 4377 25 and and CC cord-006870-f5w6fw6q 4377 26 NCS NCS NNP cord-006870-f5w6fw6q 4377 27 / / SYM cord-006870-f5w6fw6q 4377 28 NCSE NCSE NNP cord-006870-f5w6fw6q 4377 29 cessation cessation NN cord-006870-f5w6fw6q 4377 30 . . . cord-006870-f5w6fw6q 4378 1 Of of IN cord-006870-f5w6fw6q 4378 2 the the DT cord-006870-f5w6fw6q 4378 3 17 17 CD cord-006870-f5w6fw6q 4378 4 patients patient NNS cord-006870-f5w6fw6q 4378 5 included include VBN cord-006870-f5w6fw6q 4378 6 in in IN cord-006870-f5w6fw6q 4378 7 this this DT cord-006870-f5w6fw6q 4378 8 study study NN cord-006870-f5w6fw6q 4378 9 , , , cord-006870-f5w6fw6q 4378 10 7 7 CD cord-006870-f5w6fw6q 4378 11 ( ( -LRB- cord-006870-f5w6fw6q 4378 12 41 41 CD cord-006870-f5w6fw6q 4378 13 % % NN cord-006870-f5w6fw6q 4378 14 ) ) -RRB- cord-006870-f5w6fw6q 4378 15 had have VBD cord-006870-f5w6fw6q 4378 16 NCS NCS NNP cord-006870-f5w6fw6q 4378 17 vs. vs. IN cord-006870-f5w6fw6q 4378 18 10 10 CD cord-006870-f5w6fw6q 4378 19 ( ( -LRB- cord-006870-f5w6fw6q 4378 20 59 59 CD cord-006870-f5w6fw6q 4378 21 % % NN cord-006870-f5w6fw6q 4378 22 ) ) -RRB- cord-006870-f5w6fw6q 4378 23 with with IN cord-006870-f5w6fw6q 4378 24 NCSE NCSE NNP cord-006870-f5w6fw6q 4378 25 . . . cord-006870-f5w6fw6q 4379 1 The the DT cord-006870-f5w6fw6q 4379 2 most most RBS cord-006870-f5w6fw6q 4379 3 common common JJ cord-006870-f5w6fw6q 4379 4 etiologies etiology NNS cord-006870-f5w6fw6q 4379 5 were be VBD cord-006870-f5w6fw6q 4379 6 autoimmune autoimmune JJ cord-006870-f5w6fw6q 4379 7 ( ( -LRB- cord-006870-f5w6fw6q 4379 8 n=6 n=6 JJ cord-006870-f5w6fw6q 4379 9 ) ) -RRB- cord-006870-f5w6fw6q 4379 10 and and CC cord-006870-f5w6fw6q 4379 11 CNS CNS NNP cord-006870-f5w6fw6q 4379 12 tumor tumor NN cord-006870-f5w6fw6q 4379 13 ( ( -LRB- cord-006870-f5w6fw6q 4379 14 n=5 n=5 NNP cord-006870-f5w6fw6q 4379 15 ) ) -RRB- cord-006870-f5w6fw6q 4379 16 , , . cord-006870-f5w6fw6q 4380 1 with with IN cord-006870-f5w6fw6q 4380 2 7 7 CD cord-006870-f5w6fw6q 4380 3 patients patient NNS cord-006870-f5w6fw6q 4380 4 ( ( -LRB- cord-006870-f5w6fw6q 4380 5 41 41 CD cord-006870-f5w6fw6q 4380 6 % % NN cord-006870-f5w6fw6q 4380 7 ) ) -RRB- cord-006870-f5w6fw6q 4380 8 having have VBG cord-006870-f5w6fw6q 4380 9 pre pre VBN cord-006870-f5w6fw6q 4380 10 - - JJ cord-006870-f5w6fw6q 4380 11 existing existing JJ cord-006870-f5w6fw6q 4380 12 epilepsy epilepsy NN cord-006870-f5w6fw6q 4380 13 . . . cord-006870-f5w6fw6q 4381 1 Clobazam Clobazam NNP cord-006870-f5w6fw6q 4381 2 was be VBD cord-006870-f5w6fw6q 4381 3 the the DT cord-006870-f5w6fw6q 4381 4 last last JJ cord-006870-f5w6fw6q 4381 5 AED AED NNP cord-006870-f5w6fw6q 4381 6 added add VBD cord-006870-f5w6fw6q 4381 7 before before IN cord-006870-f5w6fw6q 4381 8 cessation cessation NN cord-006870-f5w6fw6q 4381 9 of of IN cord-006870-f5w6fw6q 4381 10 NCS NCS NNP cord-006870-f5w6fw6q 4381 11 / / SYM cord-006870-f5w6fw6q 4381 12 NCSE NCSE NNP cord-006870-f5w6fw6q 4381 13 in in IN cord-006870-f5w6fw6q 4381 14 12 12 CD cord-006870-f5w6fw6q 4381 15 of of IN cord-006870-f5w6fw6q 4381 16 17 17 CD cord-006870-f5w6fw6q 4381 17 ( ( -LRB- cord-006870-f5w6fw6q 4381 18 71 71 CD cord-006870-f5w6fw6q 4381 19 % % NN cord-006870-f5w6fw6q 4381 20 ) ) -RRB- cord-006870-f5w6fw6q 4381 21 subjects subject NNS cord-006870-f5w6fw6q 4381 22 . . . cord-006870-f5w6fw6q 4382 1 Clobazam Clobazam NNP cord-006870-f5w6fw6q 4382 2 was be VBD cord-006870-f5w6fw6q 4382 3 chosen choose VBN cord-006870-f5w6fw6q 4382 4 as as IN cord-006870-f5w6fw6q 4382 5 the the DT cord-006870-f5w6fw6q 4382 6 3rd 3rd NN cord-006870-f5w6fw6q 4382 7 to to IN cord-006870-f5w6fw6q 4382 8 6th 6th JJ cord-006870-f5w6fw6q 4382 9 line line NN cord-006870-f5w6fw6q 4382 10 agent agent NN cord-006870-f5w6fw6q 4382 11 . . . cord-006870-f5w6fw6q 4383 1 Clobazam Clobazam NNP cord-006870-f5w6fw6q 4383 2 was be VBD cord-006870-f5w6fw6q 4383 3 started start VBN cord-006870-f5w6fw6q 4383 4 at at IN cord-006870-f5w6fw6q 4383 5 a a DT cord-006870-f5w6fw6q 4383 6 median median NN cord-006870-f5w6fw6q 4383 7 of of IN cord-006870-f5w6fw6q 4383 8 2 2 CD cord-006870-f5w6fw6q 4383 9 days day NNS cord-006870-f5w6fw6q 4383 10 from from IN cord-006870-f5w6fw6q 4383 11 the the DT cord-006870-f5w6fw6q 4383 12 onset onset NN cord-006870-f5w6fw6q 4383 13 NCS NCS NNP cord-006870-f5w6fw6q 4383 14 / / SYM cord-006870-f5w6fw6q 4383 15 NCSE NCSE NNP cord-006870-f5w6fw6q 4383 16 ( ( -LRB- cord-006870-f5w6fw6q 4383 17 range range NNP cord-006870-f5w6fw6q 4383 18 1 1 CD cord-006870-f5w6fw6q 4383 19 - - SYM cord-006870-f5w6fw6q 4383 20 55 55 CD cord-006870-f5w6fw6q 4383 21 days day NNS cord-006870-f5w6fw6q 4383 22 ) ) -RRB- cord-006870-f5w6fw6q 4383 23 . . . cord-006870-f5w6fw6q 4384 1 The the DT cord-006870-f5w6fw6q 4384 2 median median JJ cord-006870-f5w6fw6q 4384 3 total total JJ cord-006870-f5w6fw6q 4384 4 daily daily JJ cord-006870-f5w6fw6q 4384 5 dose dose NN cord-006870-f5w6fw6q 4384 6 of of IN cord-006870-f5w6fw6q 4384 7 clobazam clobazam NNP cord-006870-f5w6fw6q 4384 8 was be VBD cord-006870-f5w6fw6q 4384 9 20 20 CD cord-006870-f5w6fw6q 4384 10 mg mg NNP cord-006870-f5w6fw6q 4384 11 ( ( -LRB- cord-006870-f5w6fw6q 4384 12 range range NNP cord-006870-f5w6fw6q 4384 13 10 10 CD cord-006870-f5w6fw6q 4384 14 - - SYM cord-006870-f5w6fw6q 4384 15 60 60 CD cord-006870-f5w6fw6q 4384 16 mg mg NNP cord-006870-f5w6fw6q 4384 17 ) ) -RRB- cord-006870-f5w6fw6q 4384 18 . . . cord-006870-f5w6fw6q 4385 1 This this DT cord-006870-f5w6fw6q 4385 2 study study NN cord-006870-f5w6fw6q 4385 3 suggests suggest VBZ cord-006870-f5w6fw6q 4385 4 that that IN cord-006870-f5w6fw6q 4385 5 clobazam clobazam NNP cord-006870-f5w6fw6q 4385 6 may may MD cord-006870-f5w6fw6q 4385 7 be be VB cord-006870-f5w6fw6q 4385 8 effective effective JJ cord-006870-f5w6fw6q 4385 9 at at IN cord-006870-f5w6fw6q 4385 10 various various JJ cord-006870-f5w6fw6q 4385 11 time time NN cord-006870-f5w6fw6q 4385 12 points point NNS cord-006870-f5w6fw6q 4385 13 in in IN cord-006870-f5w6fw6q 4385 14 the the DT cord-006870-f5w6fw6q 4385 15 treatment treatment NN cord-006870-f5w6fw6q 4385 16 of of IN cord-006870-f5w6fw6q 4385 17 NCS NCS NNP cord-006870-f5w6fw6q 4385 18 / / SYM cord-006870-f5w6fw6q 4385 19 NSCE NSCE NNP cord-006870-f5w6fw6q 4385 20 and and CC cord-006870-f5w6fw6q 4385 21 may may MD cord-006870-f5w6fw6q 4385 22 prevent prevent VB cord-006870-f5w6fw6q 4385 23 the the DT cord-006870-f5w6fw6q 4385 24 need need NN cord-006870-f5w6fw6q 4385 25 for for IN cord-006870-f5w6fw6q 4385 26 addition addition NN cord-006870-f5w6fw6q 4385 27 of of IN cord-006870-f5w6fw6q 4385 28 intravenous intravenous JJ cord-006870-f5w6fw6q 4385 29 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4385 30 drugs drug NNS cord-006870-f5w6fw6q 4385 31 to to TO cord-006870-f5w6fw6q 4385 32 control control VB cord-006870-f5w6fw6q 4385 33 seizures seizure NNS cord-006870-f5w6fw6q 4385 34 . . . cord-006870-f5w6fw6q 4386 1 However however RB cord-006870-f5w6fw6q 4386 2 , , , cord-006870-f5w6fw6q 4386 3 a a DT cord-006870-f5w6fw6q 4386 4 prospective prospective JJ cord-006870-f5w6fw6q 4386 5 study study NN cord-006870-f5w6fw6q 4386 6 is be VBZ cord-006870-f5w6fw6q 4386 7 warranted warrant VBN cord-006870-f5w6fw6q 4386 8 to to TO cord-006870-f5w6fw6q 4386 9 determine determine VB cord-006870-f5w6fw6q 4386 10 efficacy efficacy NN cord-006870-f5w6fw6q 4386 11 and and CC cord-006870-f5w6fw6q 4386 12 optimal optimal JJ cord-006870-f5w6fw6q 4386 13 dosing dosing NN cord-006870-f5w6fw6q 4386 14 . . . cord-006870-f5w6fw6q 4387 1 Continuous continuous JJ cord-006870-f5w6fw6q 4387 2 electroencephalography electroencephalography NN cord-006870-f5w6fw6q 4387 3 monitoring(cEEGM monitoring(ceegm NN cord-006870-f5w6fw6q 4387 4 ) ) -RRB- cord-006870-f5w6fw6q 4388 1 with with IN cord-006870-f5w6fw6q 4388 2 international international JJ cord-006870-f5w6fw6q 4388 3 10 10 CD cord-006870-f5w6fw6q 4388 4 - - SYM cord-006870-f5w6fw6q 4388 5 20 20 CD cord-006870-f5w6fw6q 4388 6 system system NN cord-006870-f5w6fw6q 4388 7 is be VBZ cord-006870-f5w6fw6q 4388 8 essential essential JJ cord-006870-f5w6fw6q 4388 9 for for IN cord-006870-f5w6fw6q 4388 10 detect detect VB cord-006870-f5w6fw6q 4388 11 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 4388 12 status status NN cord-006870-f5w6fw6q 4388 13 epilepticus epilepticus NN cord-006870-f5w6fw6q 4388 14 ( ( -LRB- cord-006870-f5w6fw6q 4388 15 NCSE NCSE NNP cord-006870-f5w6fw6q 4388 16 ) ) -RRB- cord-006870-f5w6fw6q 4388 17 . . . cord-006870-f5w6fw6q 4389 1 In in IN cord-006870-f5w6fw6q 4389 2 Japan Japan NNP cord-006870-f5w6fw6q 4389 3 , , , cord-006870-f5w6fw6q 4389 4 both both DT cord-006870-f5w6fw6q 4389 5 cEEGM ceegm NN cord-006870-f5w6fw6q 4389 6 systems system NNS cord-006870-f5w6fw6q 4389 7 and and CC cord-006870-f5w6fw6q 4389 8 human human JJ cord-006870-f5w6fw6q 4389 9 resources resource NNS cord-006870-f5w6fw6q 4389 10 are be VBP cord-006870-f5w6fw6q 4389 11 lacking lack VBG cord-006870-f5w6fw6q 4389 12 , , , cord-006870-f5w6fw6q 4389 13 and and CC cord-006870-f5w6fw6q 4389 14 few few JJ cord-006870-f5w6fw6q 4389 15 facilities facility NNS cord-006870-f5w6fw6q 4389 16 are be VBP cord-006870-f5w6fw6q 4389 17 able able JJ cord-006870-f5w6fw6q 4389 18 to to TO cord-006870-f5w6fw6q 4389 19 conduct conduct VB cord-006870-f5w6fw6q 4389 20 such such JJ cord-006870-f5w6fw6q 4389 21 advanced advanced JJ cord-006870-f5w6fw6q 4389 22 monitoring monitoring NN cord-006870-f5w6fw6q 4389 23 . . . cord-006870-f5w6fw6q 4390 1 The the DT cord-006870-f5w6fw6q 4390 2 cEEGM ceegm NN cord-006870-f5w6fw6q 4390 3 headset headset NN cord-006870-f5w6fw6q 4390 4 , , , cord-006870-f5w6fw6q 4390 5 described describe VBN cord-006870-f5w6fw6q 4390 6 in in IN cord-006870-f5w6fw6q 4390 7 this this DT cord-006870-f5w6fw6q 4390 8 report report NN cord-006870-f5w6fw6q 4390 9 , , , cord-006870-f5w6fw6q 4390 10 is be VBZ cord-006870-f5w6fw6q 4390 11 a a DT cord-006870-f5w6fw6q 4390 12 novel novel JJ cord-006870-f5w6fw6q 4390 13 and and CC cord-006870-f5w6fw6q 4390 14 easy easy JJ cord-006870-f5w6fw6q 4390 15 - - HYPH cord-006870-f5w6fw6q 4390 16 to to IN cord-006870-f5w6fw6q 4390 17 - - HYPH cord-006870-f5w6fw6q 4390 18 use use NN cord-006870-f5w6fw6q 4390 19 technology technology NN cord-006870-f5w6fw6q 4390 20 . . . cord-006870-f5w6fw6q 4391 1 We -PRON- PRP cord-006870-f5w6fw6q 4391 2 attempted attempt VBD cord-006870-f5w6fw6q 4391 3 to to TO cord-006870-f5w6fw6q 4391 4 validate validate VB cord-006870-f5w6fw6q 4391 5 the the DT cord-006870-f5w6fw6q 4391 6 novel novel JJ cord-006870-f5w6fw6q 4391 7 cEEGM ceegm NN cord-006870-f5w6fw6q 4391 8 headset headset NN cord-006870-f5w6fw6q 4391 9 by by IN cord-006870-f5w6fw6q 4391 10 comparing compare VBG cord-006870-f5w6fw6q 4391 11 it -PRON- PRP cord-006870-f5w6fw6q 4391 12 with with IN cord-006870-f5w6fw6q 4391 13 a a DT cord-006870-f5w6fw6q 4391 14 conventional conventional JJ cord-006870-f5w6fw6q 4391 15 , , , cord-006870-f5w6fw6q 4391 16 international international JJ cord-006870-f5w6fw6q 4391 17 10 10 CD cord-006870-f5w6fw6q 4391 18 - - SYM cord-006870-f5w6fw6q 4391 19 20 20 CD cord-006870-f5w6fw6q 4391 20 cEEGM ceegm NN cord-006870-f5w6fw6q 4391 21 system system NN cord-006870-f5w6fw6q 4391 22 ( ( -LRB- cord-006870-f5w6fw6q 4391 23 conventional conventional JJ cord-006870-f5w6fw6q 4391 24 cEEGM ceegm NN cord-006870-f5w6fw6q 4391 25 ) ) -RRB- cord-006870-f5w6fw6q 4391 26 . . . cord-006870-f5w6fw6q 4392 1 We -PRON- PRP cord-006870-f5w6fw6q 4392 2 completed complete VBD cord-006870-f5w6fw6q 4392 3 this this DT cord-006870-f5w6fw6q 4392 4 study study NN cord-006870-f5w6fw6q 4392 5 at at IN cord-006870-f5w6fw6q 4392 6 a a DT cord-006870-f5w6fw6q 4392 7 single single JJ cord-006870-f5w6fw6q 4392 8 center center NN cord-006870-f5w6fw6q 4392 9 , , , cord-006870-f5w6fw6q 4392 10 eight eight CD cord-006870-f5w6fw6q 4392 11 - - HYPH cord-006870-f5w6fw6q 4392 12 bed bed NN cord-006870-f5w6fw6q 4392 13 neurocritical neurocritical NNP cord-006870-f5w6fw6q 4392 14 care care NN cord-006870-f5w6fw6q 4392 15 unit unit NN cord-006870-f5w6fw6q 4392 16 , , , cord-006870-f5w6fw6q 4392 17 between between IN cord-006870-f5w6fw6q 4392 18 January January NNP cord-006870-f5w6fw6q 4392 19 2017 2017 CD cord-006870-f5w6fw6q 4392 20 and and CC cord-006870-f5w6fw6q 4392 21 June June NNP cord-006870-f5w6fw6q 4392 22 2017 2017 CD cord-006870-f5w6fw6q 4392 23 . . . cord-006870-f5w6fw6q 4393 1 The the DT cord-006870-f5w6fw6q 4393 2 new new JJ cord-006870-f5w6fw6q 4393 3 , , , cord-006870-f5w6fw6q 4393 4 cEEGM ceegm JJ cord-006870-f5w6fw6q 4393 5 headset headset NN cord-006870-f5w6fw6q 4393 6 features feature VBZ cord-006870-f5w6fw6q 4393 7 eight eight CD cord-006870-f5w6fw6q 4393 8 electrodes electrode NNS cord-006870-f5w6fw6q 4393 9 ( ( -LRB- cord-006870-f5w6fw6q 4393 10 F F NNP cord-006870-f5w6fw6q 4393 11 , , , cord-006870-f5w6fw6q 4393 12 C C NNP cord-006870-f5w6fw6q 4393 13 , , , cord-006870-f5w6fw6q 4393 14 T T NNP cord-006870-f5w6fw6q 4393 15 , , , cord-006870-f5w6fw6q 4393 16 O O NNP cord-006870-f5w6fw6q 4393 17 ) ) -RRB- cord-006870-f5w6fw6q 4393 18 , , , cord-006870-f5w6fw6q 4393 19 and and CC cord-006870-f5w6fw6q 4393 20 is be VBZ cord-006870-f5w6fw6q 4393 21 capable capable JJ cord-006870-f5w6fw6q 4393 22 of of IN cord-006870-f5w6fw6q 4393 23 simultaneously simultaneously RB cord-006870-f5w6fw6q 4393 24 transmitting transmit VBG cord-006870-f5w6fw6q 4393 25 EEG EEG NNP cord-006870-f5w6fw6q 4393 26 data datum NNS cord-006870-f5w6fw6q 4393 27 by by IN cord-006870-f5w6fw6q 4393 28 Bluetooth Bluetooth NNP cord-006870-f5w6fw6q 4393 29 . . . cord-006870-f5w6fw6q 4394 1 Patients patient NNS cord-006870-f5w6fw6q 4394 2 with with IN cord-006870-f5w6fw6q 4394 3 disturbed disturbed JJ cord-006870-f5w6fw6q 4394 4 consciousness consciousness NN cord-006870-f5w6fw6q 4394 5 , , , cord-006870-f5w6fw6q 4394 6 of of IN cord-006870-f5w6fw6q 4394 7 unknown unknown JJ cord-006870-f5w6fw6q 4394 8 etiology etiology NN cord-006870-f5w6fw6q 4394 9 , , , cord-006870-f5w6fw6q 4394 10 underwent undergo VBD cord-006870-f5w6fw6q 4394 11 cEEGM ceegm JJ cord-006870-f5w6fw6q 4394 12 headset headset NN cord-006870-f5w6fw6q 4394 13 followed follow VBN cord-006870-f5w6fw6q 4394 14 by by IN cord-006870-f5w6fw6q 4394 15 conventional conventional JJ cord-006870-f5w6fw6q 4394 16 cEEGM ceegm NN cord-006870-f5w6fw6q 4394 17 . . . cord-006870-f5w6fw6q 4395 1 We -PRON- PRP cord-006870-f5w6fw6q 4395 2 verified verify VBD cord-006870-f5w6fw6q 4395 3 the the DT cord-006870-f5w6fw6q 4395 4 concordance concordance NN cord-006870-f5w6fw6q 4395 5 rate rate NN cord-006870-f5w6fw6q 4395 6 of of IN cord-006870-f5w6fw6q 4395 7 the the DT cord-006870-f5w6fw6q 4395 8 two two CD cord-006870-f5w6fw6q 4395 9 systems system NNS cord-006870-f5w6fw6q 4395 10 for for IN cord-006870-f5w6fw6q 4395 11 detecting detect VBG cord-006870-f5w6fw6q 4395 12 EEG EEG NNP cord-006870-f5w6fw6q 4395 13 morphologies morphology NNS cord-006870-f5w6fw6q 4395 14 ( ( -LRB- cord-006870-f5w6fw6q 4395 15 e.g. e.g. IN cord-006870-f5w6fw6q 4395 16 periodic periodic JJ cord-006870-f5w6fw6q 4395 17 discharges discharge NNS cord-006870-f5w6fw6q 4395 18 , , , cord-006870-f5w6fw6q 4395 19 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4395 20 delta delta NN cord-006870-f5w6fw6q 4395 21 activity activity NN cord-006870-f5w6fw6q 4395 22 , , , cord-006870-f5w6fw6q 4395 23 spikes spike NNS cord-006870-f5w6fw6q 4395 24 and and CC cord-006870-f5w6fw6q 4395 25 waves wave NNS cord-006870-f5w6fw6q 4395 26 ) ) -RRB- cord-006870-f5w6fw6q 4395 27 , , , cord-006870-f5w6fw6q 4395 28 and and CC cord-006870-f5w6fw6q 4395 29 diagnosing diagnose VBG cord-006870-f5w6fw6q 4395 30 NCSE NCSE NNP cord-006870-f5w6fw6q 4395 31 . . . cord-006870-f5w6fw6q 4396 1 EEG EEG NNP cord-006870-f5w6fw6q 4396 2 morphologies morphology NNS cord-006870-f5w6fw6q 4396 3 were be VBD cord-006870-f5w6fw6q 4396 4 appreciated appreciate VBN cord-006870-f5w6fw6q 4396 5 according accord VBG cord-006870-f5w6fw6q 4396 6 to to IN cord-006870-f5w6fw6q 4396 7 " " `` cord-006870-f5w6fw6q 4396 8 American American NNP cord-006870-f5w6fw6q 4396 9 Clinical Clinical NNP cord-006870-f5w6fw6q 4396 10 Neurophysiology Neurophysiology NNP cord-006870-f5w6fw6q 4396 11 Society Society NNP cord-006870-f5w6fw6q 4396 12 's 's POS cord-006870-f5w6fw6q 4396 13 Standardized Standardized NNP cord-006870-f5w6fw6q 4396 14 Critical Critical NNP cord-006870-f5w6fw6q 4396 15 Care care NN cord-006870-f5w6fw6q 4396 16 EEG eeg NN cord-006870-f5w6fw6q 4396 17 Terminology terminology NN cord-006870-f5w6fw6q 4396 18 : : : cord-006870-f5w6fw6q 4396 19 2012 2012 CD cord-006870-f5w6fw6q 4396 20 version version NN cord-006870-f5w6fw6q 4396 21 " " '' cord-006870-f5w6fw6q 4396 22 and and CC cord-006870-f5w6fw6q 4396 23 diagnosis diagnosis NN cord-006870-f5w6fw6q 4396 24 of of IN cord-006870-f5w6fw6q 4396 25 NCSE NCSE NNP cord-006870-f5w6fw6q 4396 26 were be VBD cord-006870-f5w6fw6q 4396 27 done do VBN cord-006870-f5w6fw6q 4396 28 according accord VBG cord-006870-f5w6fw6q 4396 29 to to IN cord-006870-f5w6fw6q 4396 30 modified modify VBN cord-006870-f5w6fw6q 4396 31 Salzburg Salzburg NNP cord-006870-f5w6fw6q 4396 32 consensus consensus NN cord-006870-f5w6fw6q 4396 33 criteria criterion NNS cord-006870-f5w6fw6q 4396 34 . . . cord-006870-f5w6fw6q 4397 1 Among among IN cord-006870-f5w6fw6q 4397 2 this this DT cord-006870-f5w6fw6q 4397 3 period period NN cord-006870-f5w6fw6q 4397 4 , , , cord-006870-f5w6fw6q 4397 5 we -PRON- PRP cord-006870-f5w6fw6q 4397 6 enrolled enrol VBD cord-006870-f5w6fw6q 4397 7 thirty thirty CD cord-006870-f5w6fw6q 4397 8 patients patient NNS cord-006870-f5w6fw6q 4397 9 . . . cord-006870-f5w6fw6q 4398 1 Three three CD cord-006870-f5w6fw6q 4398 2 patients patient NNS cord-006870-f5w6fw6q 4398 3 were be VBD cord-006870-f5w6fw6q 4398 4 excluded exclude VBN cord-006870-f5w6fw6q 4398 5 because because IN cord-006870-f5w6fw6q 4398 6 of of IN cord-006870-f5w6fw6q 4398 7 not not RB cord-006870-f5w6fw6q 4398 8 satisfying satisfy VBG cord-006870-f5w6fw6q 4398 9 protocol protocol NN cord-006870-f5w6fw6q 4398 10 . . . cord-006870-f5w6fw6q 4399 1 Final final JJ cord-006870-f5w6fw6q 4399 2 analyses analysis NNS cord-006870-f5w6fw6q 4399 3 included include VBD cord-006870-f5w6fw6q 4399 4 verified verify VBN cord-006870-f5w6fw6q 4399 5 data datum NNS cord-006870-f5w6fw6q 4399 6 from from IN cord-006870-f5w6fw6q 4399 7 27 27 CD cord-006870-f5w6fw6q 4399 8 patients patient NNS cord-006870-f5w6fw6q 4399 9 . . . cord-006870-f5w6fw6q 4400 1 The the DT cord-006870-f5w6fw6q 4400 2 mean mean JJ cord-006870-f5w6fw6q 4400 3 age age NN cord-006870-f5w6fw6q 4400 4 was be VBD cord-006870-f5w6fw6q 4400 5 66 66 CD cord-006870-f5w6fw6q 4400 6 years year NNS cord-006870-f5w6fw6q 4400 7 old old JJ cord-006870-f5w6fw6q 4401 1 ( ( -LRB- cord-006870-f5w6fw6q 4401 2 range range NN cord-006870-f5w6fw6q 4401 3 : : : cord-006870-f5w6fw6q 4401 4 20 20 CD cord-006870-f5w6fw6q 4401 5 - - SYM cord-006870-f5w6fw6q 4401 6 86 86 CD cord-006870-f5w6fw6q 4401 7 ) ) -RRB- cord-006870-f5w6fw6q 4401 8 , , , cord-006870-f5w6fw6q 4401 9 59 59 CD cord-006870-f5w6fw6q 4401 10 % % NN cord-006870-f5w6fw6q 4401 11 were be VBD cord-006870-f5w6fw6q 4401 12 male male JJ cord-006870-f5w6fw6q 4401 13 , , , cord-006870-f5w6fw6q 4401 14 mean mean VBP cord-006870-f5w6fw6q 4401 15 Acute acute JJ cord-006870-f5w6fw6q 4401 16 Physiology Physiology NNP cord-006870-f5w6fw6q 4401 17 and and CC cord-006870-f5w6fw6q 4401 18 Chronic Chronic NNP cord-006870-f5w6fw6q 4401 19 Health Health NNP cord-006870-f5w6fw6q 4401 20 Evaluation Evaluation NNP cord-006870-f5w6fw6q 4402 1 ( ( -LRB- cord-006870-f5w6fw6q 4402 2 APACHE APACHE NNP cord-006870-f5w6fw6q 4402 3 ) ) -RRB- cord-006870-f5w6fw6q 4402 4 II II NNP cord-006870-f5w6fw6q 4402 5 score score NN cord-006870-f5w6fw6q 4402 6 was be VBD cord-006870-f5w6fw6q 4402 7 15 15 CD cord-006870-f5w6fw6q 4403 1 ( ( -LRB- cord-006870-f5w6fw6q 4403 2 range range NN cord-006870-f5w6fw6q 4403 3 : : : cord-006870-f5w6fw6q 4403 4 5 5 CD cord-006870-f5w6fw6q 4403 5 - - SYM cord-006870-f5w6fw6q 4403 6 27 27 CD cord-006870-f5w6fw6q 4403 7 ) ) -RRB- cord-006870-f5w6fw6q 4403 8 , , , cord-006870-f5w6fw6q 4403 9 and and CC cord-006870-f5w6fw6q 4403 10 mean mean VB cord-006870-f5w6fw6q 4403 11 Full full JJ cord-006870-f5w6fw6q 4403 12 Outline Outline NNP cord-006870-f5w6fw6q 4403 13 of of IN cord-006870-f5w6fw6q 4403 14 Unresponsiveness Unresponsiveness NNP cord-006870-f5w6fw6q 4403 15 ( ( -LRB- cord-006870-f5w6fw6q 4403 16 FOUR four CD cord-006870-f5w6fw6q 4403 17 ) ) -RRB- cord-006870-f5w6fw6q 4403 18 score score NN cord-006870-f5w6fw6q 4403 19 was be VBD cord-006870-f5w6fw6q 4403 20 10 10 CD cord-006870-f5w6fw6q 4404 1 ( ( -LRB- cord-006870-f5w6fw6q 4404 2 range range NN cord-006870-f5w6fw6q 4404 3 : : : cord-006870-f5w6fw6q 4404 4 6 6 CD cord-006870-f5w6fw6q 4404 5 - - SYM cord-006870-f5w6fw6q 4404 6 16 16 CD cord-006870-f5w6fw6q 4404 7 ) ) -RRB- cord-006870-f5w6fw6q 4404 8 . . . cord-006870-f5w6fw6q 4405 1 We -PRON- PRP cord-006870-f5w6fw6q 4405 2 appreciated appreciate VBD cord-006870-f5w6fw6q 4405 3 concordant concordant JJ cord-006870-f5w6fw6q 4405 4 EEG EEG NNP cord-006870-f5w6fw6q 4405 5 morphologies morphology NNS cord-006870-f5w6fw6q 4405 6 , , , cord-006870-f5w6fw6q 4405 7 and and CC cord-006870-f5w6fw6q 4405 8 NCSE NCSE NNP cord-006870-f5w6fw6q 4405 9 , , , cord-006870-f5w6fw6q 4405 10 in in IN cord-006870-f5w6fw6q 4405 11 78 78 CD cord-006870-f5w6fw6q 4405 12 % % NN cord-006870-f5w6fw6q 4405 13 ( ( -LRB- cord-006870-f5w6fw6q 4405 14 21/27 21/27 CD cord-006870-f5w6fw6q 4405 15 ) ) -RRB- cord-006870-f5w6fw6q 4405 16 , , , cord-006870-f5w6fw6q 4405 17 and and CC cord-006870-f5w6fw6q 4405 18 74 74 CD cord-006870-f5w6fw6q 4405 19 % % NN cord-006870-f5w6fw6q 4405 20 ( ( -LRB- cord-006870-f5w6fw6q 4405 21 20/27 20/27 CD cord-006870-f5w6fw6q 4405 22 ) ) -RRB- cord-006870-f5w6fw6q 4405 23 of of IN cord-006870-f5w6fw6q 4405 24 patients patient NNS cord-006870-f5w6fw6q 4405 25 , , , cord-006870-f5w6fw6q 4405 26 respectively respectively RB cord-006870-f5w6fw6q 4405 27 . . . cord-006870-f5w6fw6q 4406 1 This this DT cord-006870-f5w6fw6q 4406 2 easy easy JJ cord-006870-f5w6fw6q 4406 3 novel novel NN cord-006870-f5w6fw6q 4406 4 cEEGM ceegm NN cord-006870-f5w6fw6q 4406 5 headset headset NN cord-006870-f5w6fw6q 4406 6 may may MD cord-006870-f5w6fw6q 4406 7 be be VB cord-006870-f5w6fw6q 4406 8 useful useful JJ cord-006870-f5w6fw6q 4406 9 in in IN cord-006870-f5w6fw6q 4406 10 settings setting NNS cord-006870-f5w6fw6q 4406 11 with with IN cord-006870-f5w6fw6q 4406 12 limited limited JJ cord-006870-f5w6fw6q 4406 13 resources resource NNS cord-006870-f5w6fw6q 4406 14 or or CC cord-006870-f5w6fw6q 4406 15 access access NN cord-006870-f5w6fw6q 4406 16 to to IN cord-006870-f5w6fw6q 4406 17 conventional conventional JJ cord-006870-f5w6fw6q 4406 18 cEEGM ceegm NN cord-006870-f5w6fw6q 4406 19 technology technology NN cord-006870-f5w6fw6q 4406 20 . . . cord-006870-f5w6fw6q 4407 1 Further further JJ cord-006870-f5w6fw6q 4407 2 study study NN cord-006870-f5w6fw6q 4407 3 is be VBZ cord-006870-f5w6fw6q 4407 4 needed need VBN cord-006870-f5w6fw6q 4407 5 to to TO cord-006870-f5w6fw6q 4407 6 validate validate VB cord-006870-f5w6fw6q 4407 7 the the DT cord-006870-f5w6fw6q 4407 8 actual actual JJ cord-006870-f5w6fw6q 4407 9 diagnostic diagnostic JJ cord-006870-f5w6fw6q 4407 10 ability ability NN cord-006870-f5w6fw6q 4407 11 of of IN cord-006870-f5w6fw6q 4407 12 this this DT cord-006870-f5w6fw6q 4407 13 novel novel JJ cord-006870-f5w6fw6q 4407 14 headset headset NN cord-006870-f5w6fw6q 4407 15 . . . cord-006870-f5w6fw6q 4408 1 The the DT cord-006870-f5w6fw6q 4408 2 traditional traditional JJ cord-006870-f5w6fw6q 4408 3 approach approach NN cord-006870-f5w6fw6q 4408 4 to to IN cord-006870-f5w6fw6q 4408 5 interpreting interpret VBG cord-006870-f5w6fw6q 4408 6 EEG EEG NNP cord-006870-f5w6fw6q 4408 7 requires require VBZ cord-006870-f5w6fw6q 4408 8 physicians physician NNS cord-006870-f5w6fw6q 4408 9 with with IN cord-006870-f5w6fw6q 4408 10 formal formal JJ cord-006870-f5w6fw6q 4408 11 training training NN cord-006870-f5w6fw6q 4408 12 to to TO cord-006870-f5w6fw6q 4408 13 visually visually RB cord-006870-f5w6fw6q 4408 14 assess assess VB cord-006870-f5w6fw6q 4408 15 the the DT cord-006870-f5w6fw6q 4408 16 waveforms waveform NNS cord-006870-f5w6fw6q 4408 17 . . . cord-006870-f5w6fw6q 4409 1 This this DT cord-006870-f5w6fw6q 4409 2 approach approach NN cord-006870-f5w6fw6q 4409 3 is be VBZ cord-006870-f5w6fw6q 4409 4 less less RBR cord-006870-f5w6fw6q 4409 5 practical practical JJ cord-006870-f5w6fw6q 4409 6 in in IN cord-006870-f5w6fw6q 4409 7 critical critical JJ cord-006870-f5w6fw6q 4409 8 settings setting NNS cord-006870-f5w6fw6q 4409 9 when when WRB cord-006870-f5w6fw6q 4409 10 a a DT cord-006870-f5w6fw6q 4409 11 trained train VBN cord-006870-f5w6fw6q 4409 12 EEG EEG NNP cord-006870-f5w6fw6q 4409 13 specialist specialist NN cord-006870-f5w6fw6q 4409 14 is be VBZ cord-006870-f5w6fw6q 4409 15 not not RB cord-006870-f5w6fw6q 4409 16 readily readily RB cord-006870-f5w6fw6q 4409 17 available available JJ cord-006870-f5w6fw6q 4409 18 to to TO cord-006870-f5w6fw6q 4409 19 diagnose diagnose VB cord-006870-f5w6fw6q 4409 20 subclinical subclinical JJ cord-006870-f5w6fw6q 4409 21 seizures seizure NNS cord-006870-f5w6fw6q 4409 22 , , , cord-006870-f5w6fw6q 4409 23 such such JJ cord-006870-f5w6fw6q 4409 24 as as IN cord-006870-f5w6fw6q 4409 25 non non JJ cord-006870-f5w6fw6q 4409 26 - - JJ cord-006870-f5w6fw6q 4409 27 convulsive convulsive JJ cord-006870-f5w6fw6q 4409 28 status status NN cord-006870-f5w6fw6q 4409 29 epilepticus epilepticus NN cord-006870-f5w6fw6q 4409 30 , , , cord-006870-f5w6fw6q 4409 31 in in IN cord-006870-f5w6fw6q 4409 32 patients patient NNS cord-006870-f5w6fw6q 4409 33 with with IN cord-006870-f5w6fw6q 4409 34 altered altered JJ cord-006870-f5w6fw6q 4409 35 mental mental JJ cord-006870-f5w6fw6q 4409 36 status status NN cord-006870-f5w6fw6q 4409 37 . . . cord-006870-f5w6fw6q 4410 1 We -PRON- PRP cord-006870-f5w6fw6q 4410 2 have have VBP cord-006870-f5w6fw6q 4410 3 recently recently RB cord-006870-f5w6fw6q 4410 4 invented invent VBN cord-006870-f5w6fw6q 4410 5 an an DT cord-006870-f5w6fw6q 4410 6 algorithm algorithm NN cord-006870-f5w6fw6q 4410 7 for for IN cord-006870-f5w6fw6q 4410 8 sonifying sonifye VBG cord-006870-f5w6fw6q 4410 9 EEG EEG NNP cord-006870-f5w6fw6q 4410 10 , , , cord-006870-f5w6fw6q 4410 11 and and CC cord-006870-f5w6fw6q 4410 12 in in IN cord-006870-f5w6fw6q 4410 13 the the DT cord-006870-f5w6fw6q 4410 14 current current JJ cord-006870-f5w6fw6q 4410 15 study study NN cord-006870-f5w6fw6q 4410 16 , , , cord-006870-f5w6fw6q 4410 17 we -PRON- PRP cord-006870-f5w6fw6q 4410 18 explored explore VBD cord-006870-f5w6fw6q 4410 19 whether whether IN cord-006870-f5w6fw6q 4410 20 individuals individual NNS cord-006870-f5w6fw6q 4410 21 without without IN cord-006870-f5w6fw6q 4410 22 EEG EEG NNP cord-006870-f5w6fw6q 4410 23 training training NN cord-006870-f5w6fw6q 4410 24 can can MD cord-006870-f5w6fw6q 4410 25 detect detect VB cord-006870-f5w6fw6q 4410 26 ongoing ongoing JJ cord-006870-f5w6fw6q 4410 27 seizures seizure NNS cord-006870-f5w6fw6q 4410 28 by by IN cord-006870-f5w6fw6q 4410 29 simply simply RB cord-006870-f5w6fw6q 4410 30 listening listen VBG cord-006870-f5w6fw6q 4410 31 to to IN cord-006870-f5w6fw6q 4410 32 one one CD cord-006870-f5w6fw6q 4410 33 channel channel NN cord-006870-f5w6fw6q 4410 34 of of IN cord-006870-f5w6fw6q 4410 35 sonified sonified NNP cord-006870-f5w6fw6q 4410 36 EEG EEG NNP cord-006870-f5w6fw6q 4410 37 . . . cord-006870-f5w6fw6q 4411 1 We -PRON- PRP cord-006870-f5w6fw6q 4411 2 sonified sonifie VBD cord-006870-f5w6fw6q 4411 3 84 84 CD cord-006870-f5w6fw6q 4411 4 EEG EEG NNP cord-006870-f5w6fw6q 4411 5 samples sample NNS cord-006870-f5w6fw6q 4411 6 ( ( -LRB- cord-006870-f5w6fw6q 4411 7 15-second 15-second JJ cord-006870-f5w6fw6q 4411 8 long long NN cord-006870-f5w6fw6q 4411 9 ) ) -RRB- cord-006870-f5w6fw6q 4411 10 that that WDT cord-006870-f5w6fw6q 4411 11 represented represent VBD cord-006870-f5w6fw6q 4411 12 various various JJ cord-006870-f5w6fw6q 4411 13 conditions condition NNS cord-006870-f5w6fw6q 4411 14 commonly commonly RB cord-006870-f5w6fw6q 4411 15 seen see VBN cord-006870-f5w6fw6q 4411 16 in in IN cord-006870-f5w6fw6q 4411 17 the the DT cord-006870-f5w6fw6q 4411 18 ICU ICU NNP cord-006870-f5w6fw6q 4411 19 ( ( -LRB- cord-006870-f5w6fw6q 4411 20 7 7 CD cord-006870-f5w6fw6q 4411 21 seizures seizure NNS cord-006870-f5w6fw6q 4411 22 ; ; : cord-006870-f5w6fw6q 4411 23 25 25 CD cord-006870-f5w6fw6q 4411 24 LPD LPD NNP cord-006870-f5w6fw6q 4411 25 , , , cord-006870-f5w6fw6q 4411 26 GPD gpd NN cord-006870-f5w6fw6q 4411 27 , , , cord-006870-f5w6fw6q 4411 28 or or CC cord-006870-f5w6fw6q 4411 29 burst burst VB cord-006870-f5w6fw6q 4411 30 suppression suppression NN cord-006870-f5w6fw6q 4411 31 , , , cord-006870-f5w6fw6q 4411 32 and and CC cord-006870-f5w6fw6q 4411 33 52 52 CD cord-006870-f5w6fw6q 4411 34 normal normal JJ cord-006870-f5w6fw6q 4411 35 or or CC cord-006870-f5w6fw6q 4411 36 slowing slow VBG cord-006870-f5w6fw6q 4411 37 ) ) -RRB- cord-006870-f5w6fw6q 4411 38 . . . cord-006870-f5w6fw6q 4412 1 34 34 CD cord-006870-f5w6fw6q 4412 2 Medical medical JJ cord-006870-f5w6fw6q 4412 3 students student NNS cord-006870-f5w6fw6q 4412 4 and and CC cord-006870-f5w6fw6q 4412 5 30 30 CD cord-006870-f5w6fw6q 4412 6 nurses nurse NNS cord-006870-f5w6fw6q 4412 7 were be VBD cord-006870-f5w6fw6q 4412 8 asked ask VBN cord-006870-f5w6fw6q 4412 9 to to TO cord-006870-f5w6fw6q 4412 10 indicate indicate VB cord-006870-f5w6fw6q 4412 11 each each DT cord-006870-f5w6fw6q 4412 12 audio audio JJ cord-006870-f5w6fw6q 4412 13 sample sample NN cord-006870-f5w6fw6q 4412 14 as as IN cord-006870-f5w6fw6q 4412 15 " " `` cord-006870-f5w6fw6q 4412 16 seizure seizure NN cord-006870-f5w6fw6q 4412 17 " " '' cord-006870-f5w6fw6q 4412 18 or or CC cord-006870-f5w6fw6q 4412 19 " " `` cord-006870-f5w6fw6q 4412 20 non non JJ cord-006870-f5w6fw6q 4412 21 - - JJ cord-006870-f5w6fw6q 4412 22 seizure seizure JJ cord-006870-f5w6fw6q 4412 23 " " '' cord-006870-f5w6fw6q 4412 24 . . . cord-006870-f5w6fw6q 4413 1 We -PRON- PRP cord-006870-f5w6fw6q 4413 2 then then RB cord-006870-f5w6fw6q 4413 3 compared compare VBD cord-006870-f5w6fw6q 4413 4 their -PRON- PRP$ cord-006870-f5w6fw6q 4413 5 performance performance NN cord-006870-f5w6fw6q 4413 6 with with IN cord-006870-f5w6fw6q 4413 7 that that DT cord-006870-f5w6fw6q 4413 8 of of IN cord-006870-f5w6fw6q 4413 9 EEG EEG NNP cord-006870-f5w6fw6q 4413 10 experts expert NNS cord-006870-f5w6fw6q 4413 11 [ [ -LRB- cord-006870-f5w6fw6q 4413 12 epilepsy epilepsy NN cord-006870-f5w6fw6q 4413 13 attendings attending NNS cord-006870-f5w6fw6q 4413 14 with with IN cord-006870-f5w6fw6q 4413 15 > > XX cord-006870-f5w6fw6q 4413 16 10 10 CD cord-006870-f5w6fw6q 4413 17 years year NNS cord-006870-f5w6fw6q 4413 18 of of IN cord-006870-f5w6fw6q 4413 19 experience experience NN cord-006870-f5w6fw6q 4413 20 ( ( -LRB- cord-006870-f5w6fw6q 4413 21 n=2 n=2 NNS cord-006870-f5w6fw6q 4413 22 ) ) -RRB- cord-006870-f5w6fw6q 4413 23 and and CC cord-006870-f5w6fw6q 4413 24 epilepsy epilepsy NNP cord-006870-f5w6fw6q 4413 25 fellows fellows NNPS cord-006870-f5w6fw6q 4413 26 ( ( -LRB- cord-006870-f5w6fw6q 4413 27 n=7 n=7 NNP cord-006870-f5w6fw6q 4413 28 ) ) -RRB- cord-006870-f5w6fw6q 4413 29 ] ] -RRB- cord-006870-f5w6fw6q 4413 30 and and CC cord-006870-f5w6fw6q 4413 31 some some DT cord-006870-f5w6fw6q 4413 32 of of IN cord-006870-f5w6fw6q 4413 33 the the DT cord-006870-f5w6fw6q 4413 34 medical medical JJ cord-006870-f5w6fw6q 4413 35 students student NNS cord-006870-f5w6fw6q 4413 36 ( ( -LRB- cord-006870-f5w6fw6q 4413 37 n=29 n=29 NNP cord-006870-f5w6fw6q 4413 38 ) ) -RRB- cord-006870-f5w6fw6q 4413 39 who who WP cord-006870-f5w6fw6q 4413 40 also also RB cord-006870-f5w6fw6q 4413 41 diagnosed diagnose VBD cord-006870-f5w6fw6q 4413 42 the the DT cord-006870-f5w6fw6q 4413 43 same same JJ cord-006870-f5w6fw6q 4413 44 EEGs eeg NNS cord-006870-f5w6fw6q 4413 45 on on IN cord-006870-f5w6fw6q 4413 46 visual visual JJ cord-006870-f5w6fw6q 4413 47 display display NN cord-006870-f5w6fw6q 4413 48 . . . cord-006870-f5w6fw6q 4414 1 Non Non NNS cord-006870-f5w6fw6q 4414 2 - - NNS cord-006870-f5w6fw6q 4414 3 experts expert NNS cord-006870-f5w6fw6q 4414 4 listening listen VBG cord-006870-f5w6fw6q 4414 5 to to IN cord-006870-f5w6fw6q 4414 6 single single JJ cord-006870-f5w6fw6q 4414 7 - - HYPH cord-006870-f5w6fw6q 4414 8 channel channel NN cord-006870-f5w6fw6q 4414 9 sonified sonifie VBN cord-006870-f5w6fw6q 4414 10 EEGs EEGs NNP cord-006870-f5w6fw6q 4414 11 detected detect VBD cord-006870-f5w6fw6q 4414 12 seizures seizure NNS cord-006870-f5w6fw6q 4414 13 with with IN cord-006870-f5w6fw6q 4414 14 remarkable remarkable JJ cord-006870-f5w6fw6q 4414 15 sensitivity sensitivity NN cord-006870-f5w6fw6q 4414 16 ( ( -LRB- cord-006870-f5w6fw6q 4414 17 students student NNS cord-006870-f5w6fw6q 4414 18 : : : cord-006870-f5w6fw6q 4414 19 98±5 98±5 CD cord-006870-f5w6fw6q 4414 20 % % NN cord-006870-f5w6fw6q 4414 21 ; ; . cord-006870-f5w6fw6q 4415 1 nurses nurse NNS cord-006870-f5w6fw6q 4415 2 : : : cord-006870-f5w6fw6q 4415 3 95±14 95±14 CD cord-006870-f5w6fw6q 4415 4 % % NN cord-006870-f5w6fw6q 4415 5 ) ) -RRB- cord-006870-f5w6fw6q 4415 6 compared compare VBN cord-006870-f5w6fw6q 4415 7 to to IN cord-006870-f5w6fw6q 4415 8 experts expert NNS cord-006870-f5w6fw6q 4415 9 or or CC cord-006870-f5w6fw6q 4415 10 non non NNS cord-006870-f5w6fw6q 4415 11 - - NNS cord-006870-f5w6fw6q 4415 12 experts expert NNS cord-006870-f5w6fw6q 4415 13 reviewing review VBG cord-006870-f5w6fw6q 4415 14 the the DT cord-006870-f5w6fw6q 4415 15 same same JJ cord-006870-f5w6fw6q 4415 16 EEGs eeg NNS cord-006870-f5w6fw6q 4415 17 on on IN cord-006870-f5w6fw6q 4415 18 visual visual JJ cord-006870-f5w6fw6q 4415 19 display display NN cord-006870-f5w6fw6q 4415 20 ( ( -LRB- cord-006870-f5w6fw6q 4415 21 attendings attending NNS cord-006870-f5w6fw6q 4415 22 : : : cord-006870-f5w6fw6q 4415 23 100 100 CD cord-006870-f5w6fw6q 4415 24 % % NN cord-006870-f5w6fw6q 4415 25 ; ; : cord-006870-f5w6fw6q 4415 26 fellows fellow NNS cord-006870-f5w6fw6q 4415 27 : : : cord-006870-f5w6fw6q 4415 28 90±11 90±11 CD cord-006870-f5w6fw6q 4415 29 % % NN cord-006870-f5w6fw6q 4415 30 ; ; : cord-006870-f5w6fw6q 4415 31 students student NNS cord-006870-f5w6fw6q 4415 32 : : : cord-006870-f5w6fw6q 4415 33 76±19 76±19 CD cord-006870-f5w6fw6q 4415 34 % % NN cord-006870-f5w6fw6q 4415 35 ) ) -RRB- cord-006870-f5w6fw6q 4415 36 . . . cord-006870-f5w6fw6q 4416 1 If if IN cord-006870-f5w6fw6q 4416 2 the the DT cord-006870-f5w6fw6q 4416 3 EEGs eeg NNS cord-006870-f5w6fw6q 4416 4 contained contain VBD cord-006870-f5w6fw6q 4416 5 seizures seizure NNS cord-006870-f5w6fw6q 4416 6 or or CC cord-006870-f5w6fw6q 4416 7 seizure seizure NN cord-006870-f5w6fw6q 4416 8 - - HYPH cord-006870-f5w6fw6q 4416 9 like like JJ cord-006870-f5w6fw6q 4416 10 activity activity NN cord-006870-f5w6fw6q 4416 11 , , , cord-006870-f5w6fw6q 4416 12 non non NNS cord-006870-f5w6fw6q 4416 13 - - NNS cord-006870-f5w6fw6q 4416 14 experts expert NNS cord-006870-f5w6fw6q 4416 15 listening listen VBG cord-006870-f5w6fw6q 4416 16 to to IN cord-006870-f5w6fw6q 4416 17 sonified sonified NNP cord-006870-f5w6fw6q 4416 18 EEGs eeg NNS cord-006870-f5w6fw6q 4416 19 rated rate VBD cord-006870-f5w6fw6q 4416 20 them -PRON- PRP cord-006870-f5w6fw6q 4416 21 as as IN cord-006870-f5w6fw6q 4416 22 seizures seizure NNS cord-006870-f5w6fw6q 4416 23 with with IN cord-006870-f5w6fw6q 4416 24 high high JJ cord-006870-f5w6fw6q 4416 25 specificity specificity NN cord-006870-f5w6fw6q 4416 26 ( ( -LRB- cord-006870-f5w6fw6q 4416 27 students student NNS cord-006870-f5w6fw6q 4416 28 : : : cord-006870-f5w6fw6q 4416 29 85±9 85±9 CD cord-006870-f5w6fw6q 4416 30 % % NN cord-006870-f5w6fw6q 4416 31 ; ; : cord-006870-f5w6fw6q 4416 32 nurses nurse NNS cord-006870-f5w6fw6q 4416 33 : : : cord-006870-f5w6fw6q 4416 34 82±12 82±12 CD cord-006870-f5w6fw6q 4416 35 % % NN cord-006870-f5w6fw6q 4416 36 ) ) -RRB- cord-006870-f5w6fw6q 4416 37 compared compare VBN cord-006870-f5w6fw6q 4416 38 to to IN cord-006870-f5w6fw6q 4416 39 experts expert NNS cord-006870-f5w6fw6q 4416 40 or or CC cord-006870-f5w6fw6q 4416 41 non non NNS cord-006870-f5w6fw6q 4416 42 - - NNS cord-006870-f5w6fw6q 4416 43 experts expert NNS cord-006870-f5w6fw6q 4416 44 viewing view VBG cord-006870-f5w6fw6q 4416 45 the the DT cord-006870-f5w6fw6q 4416 46 EEGs eeg NNS cord-006870-f5w6fw6q 4416 47 visually visually RB cord-006870-f5w6fw6q 4416 48 ( ( -LRB- cord-006870-f5w6fw6q 4416 49 attendings attending NNS cord-006870-f5w6fw6q 4416 50 : : : cord-006870-f5w6fw6q 4416 51 95±1 95±1 CD cord-006870-f5w6fw6q 4416 52 % % NN cord-006870-f5w6fw6q 4416 53 ; ; : cord-006870-f5w6fw6q 4416 54 fellows fellow NNS cord-006870-f5w6fw6q 4416 55 : : : cord-006870-f5w6fw6q 4416 56 91±7 91±7 CD cord-006870-f5w6fw6q 4416 57 % % NN cord-006870-f5w6fw6q 4416 58 ; ; : cord-006870-f5w6fw6q 4416 59 students student NNS cord-006870-f5w6fw6q 4416 60 : : : cord-006870-f5w6fw6q 4416 61 65±20 65±20 CD cord-006870-f5w6fw6q 4416 62 % % NN cord-006870-f5w6fw6q 4416 63 ) ) -RRB- cord-006870-f5w6fw6q 4416 64 . . . cord-006870-f5w6fw6q 4417 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4417 2 study study NN cord-006870-f5w6fw6q 4417 3 confirms confirm VBZ cord-006870-f5w6fw6q 4417 4 that that IN cord-006870-f5w6fw6q 4417 5 individuals individual NNS cord-006870-f5w6fw6q 4417 6 without without IN cord-006870-f5w6fw6q 4417 7 EEG EEG NNP cord-006870-f5w6fw6q 4417 8 training training NN cord-006870-f5w6fw6q 4417 9 can can MD cord-006870-f5w6fw6q 4417 10 detect detect VB cord-006870-f5w6fw6q 4417 11 ongoing ongoing JJ cord-006870-f5w6fw6q 4417 12 seizures seizure NNS cord-006870-f5w6fw6q 4417 13 or or CC cord-006870-f5w6fw6q 4417 14 seizure seizure NN cord-006870-f5w6fw6q 4417 15 - - HYPH cord-006870-f5w6fw6q 4417 16 like like JJ cord-006870-f5w6fw6q 4417 17 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4417 18 periodic periodic JJ cord-006870-f5w6fw6q 4417 19 activity activity NN cord-006870-f5w6fw6q 4417 20 by by IN cord-006870-f5w6fw6q 4417 21 merely merely RB cord-006870-f5w6fw6q 4417 22 listening listen VBG cord-006870-f5w6fw6q 4417 23 to to IN cord-006870-f5w6fw6q 4417 24 short short JJ cord-006870-f5w6fw6q 4417 25 duration duration NN cord-006870-f5w6fw6q 4417 26 of of IN cord-006870-f5w6fw6q 4417 27 sonified sonifie VBN cord-006870-f5w6fw6q 4417 28 EEG EEG NNP cord-006870-f5w6fw6q 4417 29 . . . cord-006870-f5w6fw6q 4418 1 While while IN cord-006870-f5w6fw6q 4418 2 sonification sonification NN cord-006870-f5w6fw6q 4418 3 of of IN cord-006870-f5w6fw6q 4418 4 EEG EEG NNP cord-006870-f5w6fw6q 4418 5 can can MD cord-006870-f5w6fw6q 4418 6 not not RB cord-006870-f5w6fw6q 4418 7 replace replace VB cord-006870-f5w6fw6q 4418 8 the the DT cord-006870-f5w6fw6q 4418 9 traditional traditional JJ cord-006870-f5w6fw6q 4418 10 approaches approach NNS cord-006870-f5w6fw6q 4418 11 to to IN cord-006870-f5w6fw6q 4418 12 EEG EEG NNP cord-006870-f5w6fw6q 4418 13 interpretation interpretation NN cord-006870-f5w6fw6q 4418 14 , , , cord-006870-f5w6fw6q 4418 15 it -PRON- PRP cord-006870-f5w6fw6q 4418 16 provides provide VBZ cord-006870-f5w6fw6q 4418 17 a a DT cord-006870-f5w6fw6q 4418 18 meaningful meaningful JJ cord-006870-f5w6fw6q 4418 19 triage triage NN cord-006870-f5w6fw6q 4418 20 tool tool NN cord-006870-f5w6fw6q 4418 21 for for IN cord-006870-f5w6fw6q 4418 22 fast fast JJ cord-006870-f5w6fw6q 4418 23 assessment assessment NN cord-006870-f5w6fw6q 4418 24 of of IN cord-006870-f5w6fw6q 4418 25 patients patient NNS cord-006870-f5w6fw6q 4418 26 with with IN cord-006870-f5w6fw6q 4418 27 suspected suspect VBN cord-006870-f5w6fw6q 4418 28 subclinical subclinical JJ cord-006870-f5w6fw6q 4418 29 seizures seizure NNS cord-006870-f5w6fw6q 4418 30 . . . cord-006870-f5w6fw6q 4419 1 Super super JJ cord-006870-f5w6fw6q 4419 2 - - JJ cord-006870-f5w6fw6q 4419 3 refractory refractory JJ cord-006870-f5w6fw6q 4419 4 status status NN cord-006870-f5w6fw6q 4419 5 epilepticus epilepticus NN cord-006870-f5w6fw6q 4419 6 ( ( -LRB- cord-006870-f5w6fw6q 4419 7 SRSE SRSE NNP cord-006870-f5w6fw6q 4419 8 ) ) -RRB- cord-006870-f5w6fw6q 4419 9 is be VBZ cord-006870-f5w6fw6q 4419 10 a a DT cord-006870-f5w6fw6q 4419 11 life life NN cord-006870-f5w6fw6q 4419 12 - - HYPH cord-006870-f5w6fw6q 4419 13 threatening threaten VBG cord-006870-f5w6fw6q 4419 14 form form NN cord-006870-f5w6fw6q 4419 15 of of IN cord-006870-f5w6fw6q 4419 16 status status NN cord-006870-f5w6fw6q 4419 17 epilepticus epilepticus NN cord-006870-f5w6fw6q 4419 18 ( ( -LRB- cord-006870-f5w6fw6q 4419 19 SE SE NNP cord-006870-f5w6fw6q 4419 20 ) ) -RRB- cord-006870-f5w6fw6q 4419 21 that that WDT cord-006870-f5w6fw6q 4419 22 continues continue VBZ cord-006870-f5w6fw6q 4419 23 despite despite IN cord-006870-f5w6fw6q 4419 24 , , , cord-006870-f5w6fw6q 4419 25 or or CC cord-006870-f5w6fw6q 4419 26 recurs recur VBZ cord-006870-f5w6fw6q 4419 27 after after RB cord-006870-f5w6fw6q 4419 28 , , , cord-006870-f5w6fw6q 4419 29 24 24 CD cord-006870-f5w6fw6q 4419 30 hours hour NNS cord-006870-f5w6fw6q 4419 31 of of IN cord-006870-f5w6fw6q 4419 32 therapeutic therapeutic JJ cord-006870-f5w6fw6q 4419 33 interventions intervention NNS cord-006870-f5w6fw6q 4419 34 , , , cord-006870-f5w6fw6q 4419 35 including include VBG cord-006870-f5w6fw6q 4419 36 continuous continuous JJ cord-006870-f5w6fw6q 4419 37 intravenous intravenous JJ cord-006870-f5w6fw6q 4419 38 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4419 39 third third JJ cord-006870-f5w6fw6q 4419 40 - - HYPH cord-006870-f5w6fw6q 4419 41 line line NN cord-006870-f5w6fw6q 4419 42 agents agent NNS cord-006870-f5w6fw6q 4419 43 ( ( -LRB- cord-006870-f5w6fw6q 4419 44 TLAs TLAs NNP cord-006870-f5w6fw6q 4419 45 ) ) -RRB- cord-006870-f5w6fw6q 4419 46 . . . cord-006870-f5w6fw6q 4420 1 No no DT cord-006870-f5w6fw6q 4420 2 therapies therapy NNS cord-006870-f5w6fw6q 4420 3 are be VBP cord-006870-f5w6fw6q 4420 4 approved approve VBN cord-006870-f5w6fw6q 4420 5 for for IN cord-006870-f5w6fw6q 4420 6 SRSE SRSE NNP cord-006870-f5w6fw6q 4420 7 , , , cord-006870-f5w6fw6q 4420 8 leading lead VBG cord-006870-f5w6fw6q 4420 9 to to IN cord-006870-f5w6fw6q 4420 10 substantial substantial JJ cord-006870-f5w6fw6q 4420 11 variation variation NN cord-006870-f5w6fw6q 4420 12 in in IN cord-006870-f5w6fw6q 4420 13 both both DT cord-006870-f5w6fw6q 4420 14 management management NN cord-006870-f5w6fw6q 4420 15 and and CC cord-006870-f5w6fw6q 4420 16 determination determination NN cord-006870-f5w6fw6q 4420 17 of of IN cord-006870-f5w6fw6q 4420 18 treatment treatment NN cord-006870-f5w6fw6q 4420 19 response response NN cord-006870-f5w6fw6q 4420 20 . . . cord-006870-f5w6fw6q 4421 1 For for IN cord-006870-f5w6fw6q 4421 2 the the DT cord-006870-f5w6fw6q 4421 3 Phase phase NN cord-006870-f5w6fw6q 4421 4 3 3 CD cord-006870-f5w6fw6q 4421 5 trial trial NN cord-006870-f5w6fw6q 4421 6 of of IN cord-006870-f5w6fw6q 4421 7 brexanolone brexanolone NNP cord-006870-f5w6fw6q 4421 8 as as IN cord-006870-f5w6fw6q 4421 9 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4421 10 therapy therapy NN cord-006870-f5w6fw6q 4421 11 for for IN cord-006870-f5w6fw6q 4421 12 SRSE SRSE NNP cord-006870-f5w6fw6q 4421 13 involving involve VBG cord-006870-f5w6fw6q 4421 14 up up IN cord-006870-f5w6fw6q 4421 15 to to TO cord-006870-f5w6fw6q 4421 16 180 180 CD cord-006870-f5w6fw6q 4421 17 international international JJ cord-006870-f5w6fw6q 4421 18 sites site NNS cord-006870-f5w6fw6q 4421 19 , , , cord-006870-f5w6fw6q 4421 20 we -PRON- PRP cord-006870-f5w6fw6q 4421 21 developed develop VBD cord-006870-f5w6fw6q 4421 22 and and CC cord-006870-f5w6fw6q 4421 23 implemented implement VBD cord-006870-f5w6fw6q 4421 24 Clinical Clinical NNP cord-006870-f5w6fw6q 4421 25 Standardization Standardization NNP cord-006870-f5w6fw6q 4421 26 Guidelines Guidelines NNPS cord-006870-f5w6fw6q 4421 27 ( ( -LRB- cord-006870-f5w6fw6q 4421 28 CSGs csg NNS cord-006870-f5w6fw6q 4421 29 ) ) -RRB- cord-006870-f5w6fw6q 4421 30 for for IN cord-006870-f5w6fw6q 4421 31 real real JJ cord-006870-f5w6fw6q 4421 32 - - HYPH cord-006870-f5w6fw6q 4421 33 time time NN cord-006870-f5w6fw6q 4421 34 support support NN cord-006870-f5w6fw6q 4421 35 of of IN cord-006870-f5w6fw6q 4421 36 TLA TLA NNP cord-006870-f5w6fw6q 4421 37 administration administration NN cord-006870-f5w6fw6q 4421 38 , , , cord-006870-f5w6fw6q 4421 39 weaning weaning NN cord-006870-f5w6fw6q 4421 40 , , , cord-006870-f5w6fw6q 4421 41 and and CC cord-006870-f5w6fw6q 4421 42 outcome outcome NN cord-006870-f5w6fw6q 4421 43 assessment assessment NN cord-006870-f5w6fw6q 4421 44 under under IN cord-006870-f5w6fw6q 4421 45 EEG EEG NNP cord-006870-f5w6fw6q 4421 46 neuromonitoring neuromonitoring NN cord-006870-f5w6fw6q 4421 47 . . . cord-006870-f5w6fw6q 4422 1 A a DT cord-006870-f5w6fw6q 4422 2 Clinical Clinical NNP cord-006870-f5w6fw6q 4422 3 Standardization Standardization NNP cord-006870-f5w6fw6q 4422 4 Team Team NNP cord-006870-f5w6fw6q 4422 5 ( ( -LRB- cord-006870-f5w6fw6q 4422 6 CST CST NNP cord-006870-f5w6fw6q 4422 7 ) ) -RRB- cord-006870-f5w6fw6q 4422 8 , , , cord-006870-f5w6fw6q 4422 9 including include VBG cord-006870-f5w6fw6q 4422 10 investigators investigator NNS cord-006870-f5w6fw6q 4422 11 and and CC cord-006870-f5w6fw6q 4422 12 SE SE NNP cord-006870-f5w6fw6q 4422 13 experts expert NNS cord-006870-f5w6fw6q 4422 14 , , , cord-006870-f5w6fw6q 4422 15 developed develop VBD cord-006870-f5w6fw6q 4422 16 consensus consensus NN cord-006870-f5w6fw6q 4422 17 CSGs csg NNS cord-006870-f5w6fw6q 4422 18 defining define VBG cord-006870-f5w6fw6q 4422 19 acceptable acceptable JJ cord-006870-f5w6fw6q 4422 20 EEG EEG NNP cord-006870-f5w6fw6q 4422 21 patterns pattern NNS cord-006870-f5w6fw6q 4422 22 for for IN cord-006870-f5w6fw6q 4422 23 continuation continuation NN cord-006870-f5w6fw6q 4422 24 , , , cord-006870-f5w6fw6q 4422 25 termination termination NN cord-006870-f5w6fw6q 4422 26 , , , cord-006870-f5w6fw6q 4422 27 or or CC cord-006870-f5w6fw6q 4422 28 pausing pause VBG cord-006870-f5w6fw6q 4422 29 the the DT cord-006870-f5w6fw6q 4422 30 weaning weaning NN cord-006870-f5w6fw6q 4422 31 of of IN cord-006870-f5w6fw6q 4422 32 TLAs tla NNS cord-006870-f5w6fw6q 4422 33 . . . cord-006870-f5w6fw6q 4423 1 CSG CSG NNP cord-006870-f5w6fw6q 4423 2 implementation implementation NN cord-006870-f5w6fw6q 4423 3 was be VBD cord-006870-f5w6fw6q 4423 4 facilitated facilitate VBN cord-006870-f5w6fw6q 4423 5 by by IN cord-006870-f5w6fw6q 4423 6 training training NN cord-006870-f5w6fw6q 4423 7 and and CC cord-006870-f5w6fw6q 4423 8 CST CST NNP cord-006870-f5w6fw6q 4423 9 call call NN cord-006870-f5w6fw6q 4423 10 centers center NNS cord-006870-f5w6fw6q 4423 11 staffed staff VBN cord-006870-f5w6fw6q 4423 12 internationally internationally RB cord-006870-f5w6fw6q 4423 13 by by IN cord-006870-f5w6fw6q 4423 14 physicians physician NNS cord-006870-f5w6fw6q 4423 15 with with IN cord-006870-f5w6fw6q 4423 16 critical critical JJ cord-006870-f5w6fw6q 4423 17 care care NN cord-006870-f5w6fw6q 4423 18 EEG EEG NNP cord-006870-f5w6fw6q 4423 19 expertise expertise NN cord-006870-f5w6fw6q 4423 20 . . . cord-006870-f5w6fw6q 4424 1 In in IN cord-006870-f5w6fw6q 4424 2 cases case NNS cord-006870-f5w6fw6q 4424 3 of of IN cord-006870-f5w6fw6q 4424 4 disagreement disagreement NN cord-006870-f5w6fw6q 4424 5 , , , cord-006870-f5w6fw6q 4424 6 the the DT cord-006870-f5w6fw6q 4424 7 local local JJ cord-006870-f5w6fw6q 4424 8 site site NN cord-006870-f5w6fw6q 4424 9 retained retain VBD cord-006870-f5w6fw6q 4424 10 final final JJ cord-006870-f5w6fw6q 4424 11 decision decision NN cord-006870-f5w6fw6q 4424 12 - - HYPH cord-006870-f5w6fw6q 4424 13 making make VBG cord-006870-f5w6fw6q 4424 14 authority authority NN cord-006870-f5w6fw6q 4424 15 . . . cord-006870-f5w6fw6q 4425 1 A a DT cord-006870-f5w6fw6q 4425 2 " " `` cord-006870-f5w6fw6q 4425 3 traffic traffic NN cord-006870-f5w6fw6q 4425 4 light light NN cord-006870-f5w6fw6q 4425 5 " " '' cord-006870-f5w6fw6q 4425 6 system system NN cord-006870-f5w6fw6q 4425 7 defined define VBN cord-006870-f5w6fw6q 4425 8 : : : cord-006870-f5w6fw6q 4425 9 1)"green 1)"green CD cord-006870-f5w6fw6q 4425 10 " " '' cord-006870-f5w6fw6q 4425 11 tolerated tolerate VBD cord-006870-f5w6fw6q 4425 12 EEG EEG NNP cord-006870-f5w6fw6q 4425 13 patterns pattern NNS cord-006870-f5w6fw6q 4425 14 ( ( -LRB- cord-006870-f5w6fw6q 4425 15 improving improve VBG cord-006870-f5w6fw6q 4425 16 background background NN cord-006870-f5w6fw6q 4425 17 , , , cord-006870-f5w6fw6q 4425 18 3 3 CD cord-006870-f5w6fw6q 4425 19 seizures seizure NNS cord-006870-f5w6fw6q 4425 20 within within IN cord-006870-f5w6fw6q 4425 21 3 3 CD cord-006870-f5w6fw6q 4425 22 hours hour NNS cord-006870-f5w6fw6q 4425 23 , , , cord-006870-f5w6fw6q 4425 24 discharges discharge VBZ cord-006870-f5w6fw6q 4425 25 > > XX cord-006870-f5w6fw6q 4425 26 3 3 CD cord-006870-f5w6fw6q 4425 27 Hz Hz NNP cord-006870-f5w6fw6q 4425 28 , , , cord-006870-f5w6fw6q 4425 29 or or CC cord-006870-f5w6fw6q 4425 30 discharges discharge VBZ cord-006870-f5w6fw6q 4425 31 1 1 CD cord-006870-f5w6fw6q 4425 32 - - SYM cord-006870-f5w6fw6q 4425 33 2.9 2.9 CD cord-006870-f5w6fw6q 4425 34 Hz Hz NNP cord-006870-f5w6fw6q 4425 35 with with IN cord-006870-f5w6fw6q 4425 36 evolution evolution NN cord-006870-f5w6fw6q 4425 37 and and CC cord-006870-f5w6fw6q 4425 38 no no DT cord-006870-f5w6fw6q 4425 39 improvement improvement NN cord-006870-f5w6fw6q 4425 40 over over IN cord-006870-f5w6fw6q 4425 41 6 6 CD cord-006870-f5w6fw6q 4425 42 hours hour NNS cord-006870-f5w6fw6q 4425 43 ) ) -RRB- cord-006870-f5w6fw6q 4425 44 , , , cord-006870-f5w6fw6q 4425 45 and and CC cord-006870-f5w6fw6q 4425 46 3)"amber 3)"amber CD cord-006870-f5w6fw6q 4425 47 " " `` cord-006870-f5w6fw6q 4425 48 EEG EEG NNP cord-006870-f5w6fw6q 4425 49 patterns pattern NNS cord-006870-f5w6fw6q 4425 50 not not RB cord-006870-f5w6fw6q 4425 51 meeting meet VBG cord-006870-f5w6fw6q 4425 52 the the DT cord-006870-f5w6fw6q 4425 53 above above RB cord-006870-f5w6fw6q 4425 54 , , , cord-006870-f5w6fw6q 4425 55 for for IN cord-006870-f5w6fw6q 4425 56 which which WDT cord-006870-f5w6fw6q 4425 57 TLA tla NN cord-006870-f5w6fw6q 4425 58 weaning weaning NN cord-006870-f5w6fw6q 4425 59 should should MD cord-006870-f5w6fw6q 4425 60 be be VB cord-006870-f5w6fw6q 4425 61 paused pause VBN cord-006870-f5w6fw6q 4425 62 while while IN cord-006870-f5w6fw6q 4425 63 optimizing optimize VBG cord-006870-f5w6fw6q 4425 64 anti anti JJ cord-006870-f5w6fw6q 4425 65 - - JJ cord-006870-f5w6fw6q 4425 66 epileptic epileptic JJ cord-006870-f5w6fw6q 4425 67 medications medication NNS cord-006870-f5w6fw6q 4425 68 and and CC cord-006870-f5w6fw6q 4425 69 monitoring monitoring NN cord-006870-f5w6fw6q 4425 70 for for IN cord-006870-f5w6fw6q 4425 71 transitions transition NNS cord-006870-f5w6fw6q 4425 72 to to IN cord-006870-f5w6fw6q 4425 73 green green JJ cord-006870-f5w6fw6q 4425 74 / / SYM cord-006870-f5w6fw6q 4425 75 red red JJ cord-006870-f5w6fw6q 4425 76 EEG EEG NNP cord-006870-f5w6fw6q 4425 77 patterns pattern NNS cord-006870-f5w6fw6q 4425 78 . . . cord-006870-f5w6fw6q 4426 1 The the DT cord-006870-f5w6fw6q 4426 2 initial initial JJ cord-006870-f5w6fw6q 4426 3 125 125 CD cord-006870-f5w6fw6q 4426 4 CST CST NNP cord-006870-f5w6fw6q 4426 5 consultations consultation NNS cord-006870-f5w6fw6q 4426 6 yielded yield VBD cord-006870-f5w6fw6q 4426 7 97 97 CD cord-006870-f5w6fw6q 4426 8 % % NN cord-006870-f5w6fw6q 4426 9 CSG CSG NNP cord-006870-f5w6fw6q 4426 10 compliance compliance NN cord-006870-f5w6fw6q 4426 11 ; ; : cord-006870-f5w6fw6q 4426 12 83 83 CD cord-006870-f5w6fw6q 4426 13 % % NN cord-006870-f5w6fw6q 4426 14 of of IN cord-006870-f5w6fw6q 4426 15 EEGs eeg NNS cord-006870-f5w6fw6q 4426 16 underwent undergo VBD cord-006870-f5w6fw6q 4426 17 CST CST NNP cord-006870-f5w6fw6q 4426 18 review review NN cord-006870-f5w6fw6q 4426 19 . . . cord-006870-f5w6fw6q 4427 1 Few few JJ cord-006870-f5w6fw6q 4427 2 CST CST NNP cord-006870-f5w6fw6q 4427 3 consultations consultation NNS cord-006870-f5w6fw6q 4427 4 lasted last VBD cord-006870-f5w6fw6q 4427 5 > > XX cord-006870-f5w6fw6q 4427 6 60 60 CD cord-006870-f5w6fw6q 4427 7 minutes minute NNS cord-006870-f5w6fw6q 4427 8 ( ( -LRB- cord-006870-f5w6fw6q 4427 9 7 7 CD cord-006870-f5w6fw6q 4427 10 % % NN cord-006870-f5w6fw6q 4427 11 ) ) -RRB- cord-006870-f5w6fw6q 4427 12 ; ; : cord-006870-f5w6fw6q 4427 13 most most RBS cord-006870-f5w6fw6q 4427 14 lasted last VBD cord-006870-f5w6fw6q 4427 15 < < XX cord-006870-f5w6fw6q 4427 16 30 30 CD cord-006870-f5w6fw6q 4427 17 minutes minute NNS cord-006870-f5w6fw6q 4427 18 ( ( -LRB- cord-006870-f5w6fw6q 4427 19 67 67 CD cord-006870-f5w6fw6q 4427 20 % % NN cord-006870-f5w6fw6q 4427 21 ) ) -RRB- cord-006870-f5w6fw6q 4427 22 . . . cord-006870-f5w6fw6q 4428 1 This this DT cord-006870-f5w6fw6q 4428 2 Phase phase NN cord-006870-f5w6fw6q 4428 3 3 3 CD cord-006870-f5w6fw6q 4428 4 trial trial NN cord-006870-f5w6fw6q 4428 5 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 4428 6 the the DT cord-006870-f5w6fw6q 4428 7 feasibility feasibility NN cord-006870-f5w6fw6q 4428 8 of of IN cord-006870-f5w6fw6q 4428 9 applying apply VBG cord-006870-f5w6fw6q 4428 10 neuromonitoring neuromonitore VBG cord-006870-f5w6fw6q 4428 11 CSGs csg NNS cord-006870-f5w6fw6q 4428 12 for for IN cord-006870-f5w6fw6q 4428 13 TLA tla NN cord-006870-f5w6fw6q 4428 14 weaning weaning NN cord-006870-f5w6fw6q 4428 15 in in IN cord-006870-f5w6fw6q 4428 16 SRSE SRSE NNP cord-006870-f5w6fw6q 4428 17 patients patient NNS cord-006870-f5w6fw6q 4428 18 , , , cord-006870-f5w6fw6q 4428 19 to to TO cord-006870-f5w6fw6q 4428 20 ensure ensure VB cord-006870-f5w6fw6q 4428 21 better well JJR cord-006870-f5w6fw6q 4428 22 consistency consistency NN cord-006870-f5w6fw6q 4428 23 of of IN cord-006870-f5w6fw6q 4428 24 clinical clinical JJ cord-006870-f5w6fw6q 4428 25 care care NN cord-006870-f5w6fw6q 4428 26 and and CC cord-006870-f5w6fw6q 4428 27 reliability reliability NN cord-006870-f5w6fw6q 4428 28 of of IN cord-006870-f5w6fw6q 4428 29 the the DT cord-006870-f5w6fw6q 4428 30 primary primary JJ cord-006870-f5w6fw6q 4428 31 outcome outcome NN cord-006870-f5w6fw6q 4428 32 measure measure NN cord-006870-f5w6fw6q 4428 33 in in IN cord-006870-f5w6fw6q 4428 34 clinical clinical JJ cord-006870-f5w6fw6q 4428 35 trials trial NNS cord-006870-f5w6fw6q 4428 36 . . . cord-006870-f5w6fw6q 4429 1 CSGs csg NNS cord-006870-f5w6fw6q 4429 2 were be VBD cord-006870-f5w6fw6q 4429 3 well well RB cord-006870-f5w6fw6q 4429 4 accepted accept VBN cord-006870-f5w6fw6q 4429 5 by by IN cord-006870-f5w6fw6q 4429 6 investigators investigator NNS cord-006870-f5w6fw6q 4429 7 and and CC cord-006870-f5w6fw6q 4429 8 may may MD cord-006870-f5w6fw6q 4429 9 serve serve VB cord-006870-f5w6fw6q 4429 10 as as IN cord-006870-f5w6fw6q 4429 11 a a DT cord-006870-f5w6fw6q 4429 12 framework framework NN cord-006870-f5w6fw6q 4429 13 for for IN cord-006870-f5w6fw6q 4429 14 future future JJ cord-006870-f5w6fw6q 4429 15 clinical clinical JJ cord-006870-f5w6fw6q 4429 16 trials trial NNS cord-006870-f5w6fw6q 4429 17 or or CC cord-006870-f5w6fw6q 4429 18 clinical clinical JJ cord-006870-f5w6fw6q 4429 19 therapies therapy NNS cord-006870-f5w6fw6q 4429 20 in in IN cord-006870-f5w6fw6q 4429 21 SRSE SRSE NNP cord-006870-f5w6fw6q 4429 22 . . . cord-006870-f5w6fw6q 4430 1 Severe severe JJ cord-006870-f5w6fw6q 4430 2 brain brain NN cord-006870-f5w6fw6q 4430 3 trauma trauma NN cord-006870-f5w6fw6q 4430 4 is be VBZ cord-006870-f5w6fw6q 4430 5 a a DT cord-006870-f5w6fw6q 4430 6 leading leading JJ cord-006870-f5w6fw6q 4430 7 cause cause NN cord-006870-f5w6fw6q 4430 8 of of IN cord-006870-f5w6fw6q 4430 9 death death NN cord-006870-f5w6fw6q 4430 10 and and CC cord-006870-f5w6fw6q 4430 11 disability disability NN cord-006870-f5w6fw6q 4430 12 worldwide worldwide RB cord-006870-f5w6fw6q 4430 13 . . . cord-006870-f5w6fw6q 4431 1 Post post JJ cord-006870-f5w6fw6q 4431 2 - - JJ cord-006870-f5w6fw6q 4431 3 traumatic traumatic JJ cord-006870-f5w6fw6q 4431 4 epilepsy epilepsy NN cord-006870-f5w6fw6q 4431 5 ( ( -LRB- cord-006870-f5w6fw6q 4431 6 PTE PTE NNP cord-006870-f5w6fw6q 4431 7 ) ) -RRB- cord-006870-f5w6fw6q 4431 8 is be VBZ cord-006870-f5w6fw6q 4431 9 a a DT cord-006870-f5w6fw6q 4431 10 chronic chronic JJ cord-006870-f5w6fw6q 4431 11 complication complication NN cord-006870-f5w6fw6q 4431 12 that that WDT cord-006870-f5w6fw6q 4431 13 occurs occur VBZ cord-006870-f5w6fw6q 4431 14 in in IN cord-006870-f5w6fw6q 4431 15 up up IN cord-006870-f5w6fw6q 4431 16 to to TO cord-006870-f5w6fw6q 4431 17 40 40 CD cord-006870-f5w6fw6q 4431 18 % % NN cord-006870-f5w6fw6q 4431 19 of of IN cord-006870-f5w6fw6q 4431 20 cases case NNS cord-006870-f5w6fw6q 4431 21 ( ( -LRB- cord-006870-f5w6fw6q 4431 22 Frey Frey NNP cord-006870-f5w6fw6q 4431 23 , , , cord-006870-f5w6fw6q 4431 24 2003 2003 CD cord-006870-f5w6fw6q 4431 25 ; ; : cord-006870-f5w6fw6q 4431 26 Najafi Najafi NNP cord-006870-f5w6fw6q 4431 27 et et NNP cord-006870-f5w6fw6q 4431 28 al al NNP cord-006870-f5w6fw6q 4431 29 . . NNP cord-006870-f5w6fw6q 4431 30 , , , cord-006870-f5w6fw6q 4431 31 2015 2015 CD cord-006870-f5w6fw6q 4431 32 ) ) -RRB- cord-006870-f5w6fw6q 4431 33 . . . cord-006870-f5w6fw6q 4432 1 Drugs drug NNS cord-006870-f5w6fw6q 4432 2 and and CC cord-006870-f5w6fw6q 4432 3 other other JJ cord-006870-f5w6fw6q 4432 4 interventions intervention NNS cord-006870-f5w6fw6q 4432 5 to to TO cord-006870-f5w6fw6q 4432 6 prevent prevent VB cord-006870-f5w6fw6q 4432 7 epileptogenesis epileptogenesis NN cord-006870-f5w6fw6q 4432 8 would would MD cord-006870-f5w6fw6q 4432 9 likely likely RB cord-006870-f5w6fw6q 4432 10 be be VB cord-006870-f5w6fw6q 4432 11 most most RBS cord-006870-f5w6fw6q 4432 12 effective effective JJ cord-006870-f5w6fw6q 4432 13 early early RB cord-006870-f5w6fw6q 4432 14 after after IN cord-006870-f5w6fw6q 4432 15 traumatic traumatic JJ cord-006870-f5w6fw6q 4432 16 brain brain NN cord-006870-f5w6fw6q 4432 17 injury injury NN cord-006870-f5w6fw6q 4432 18 ( ( -LRB- cord-006870-f5w6fw6q 4432 19 TBI TBI NNP cord-006870-f5w6fw6q 4432 20 ) ) -RRB- cord-006870-f5w6fw6q 4432 21 , , , cord-006870-f5w6fw6q 4432 22 but but CC cord-006870-f5w6fw6q 4432 23 can can MD cord-006870-f5w6fw6q 4432 24 not not RB cord-006870-f5w6fw6q 4432 25 be be VB cord-006870-f5w6fw6q 4432 26 given give VBN cord-006870-f5w6fw6q 4432 27 indiscriminately indiscriminately RB cord-006870-f5w6fw6q 4432 28 . . . cord-006870-f5w6fw6q 4433 1 There there EX cord-006870-f5w6fw6q 4433 2 is be VBZ cord-006870-f5w6fw6q 4433 3 a a DT cord-006870-f5w6fw6q 4433 4 critical critical JJ cord-006870-f5w6fw6q 4433 5 need need NN cord-006870-f5w6fw6q 4433 6 for for IN cord-006870-f5w6fw6q 4433 7 tools tool NNS cord-006870-f5w6fw6q 4433 8 that that WDT cord-006870-f5w6fw6q 4433 9 quantify quantify VBP cord-006870-f5w6fw6q 4433 10 those those DT cord-006870-f5w6fw6q 4433 11 at at IN cord-006870-f5w6fw6q 4433 12 high high JJ cord-006870-f5w6fw6q 4433 13 risk risk NN cord-006870-f5w6fw6q 4433 14 for for IN cord-006870-f5w6fw6q 4433 15 PTE PTE NNP cord-006870-f5w6fw6q 4433 16 . . . cord-006870-f5w6fw6q 4434 1 Abnormal abnormal JJ cord-006870-f5w6fw6q 4434 2 neural neural JJ cord-006870-f5w6fw6q 4434 3 activity activity NN cord-006870-f5w6fw6q 4434 4 , , , cord-006870-f5w6fw6q 4434 5 in in IN cord-006870-f5w6fw6q 4434 6 the the DT cord-006870-f5w6fw6q 4434 7 form form NN cord-006870-f5w6fw6q 4434 8 of of IN cord-006870-f5w6fw6q 4434 9 ictal ictal JJ cord-006870-f5w6fw6q 4434 10 - - HYPH cord-006870-f5w6fw6q 4434 11 interictal interictal JJ cord-006870-f5w6fw6q 4434 12 continuum continuum NN cord-006870-f5w6fw6q 4434 13 abnormalities(IICAs abnormalities(IICAs NNP cord-006870-f5w6fw6q 4434 14 ) ) -RRB- cord-006870-f5w6fw6q 4434 15 are be VBP cord-006870-f5w6fw6q 4434 16 increased increase VBN cord-006870-f5w6fw6q 4434 17 acute acute JJ cord-006870-f5w6fw6q 4434 18 brain brain NN cord-006870-f5w6fw6q 4434 19 injuries injury NNS cord-006870-f5w6fw6q 4434 20 , , , cord-006870-f5w6fw6q 4434 21 and and CC cord-006870-f5w6fw6q 4434 22 appear appear VBP cord-006870-f5w6fw6q 4434 23 to to TO cord-006870-f5w6fw6q 4434 24 differentiate differentiate VB cord-006870-f5w6fw6q 4434 25 patients patient NNS cord-006870-f5w6fw6q 4434 26 at at IN cord-006870-f5w6fw6q 4434 27 risk risk NN cord-006870-f5w6fw6q 4434 28 for for IN cord-006870-f5w6fw6q 4434 29 secondary secondary JJ cord-006870-f5w6fw6q 4434 30 brain brain NN cord-006870-f5w6fw6q 4434 31 injury injury NN cord-006870-f5w6fw6q 4434 32 ( ( -LRB- cord-006870-f5w6fw6q 4434 33 e.g. e.g. RB cord-006870-f5w6fw6q 4434 34 Kim Kim NNP cord-006870-f5w6fw6q 4434 35 et et NNP cord-006870-f5w6fw6q 4434 36 al al NNP cord-006870-f5w6fw6q 4434 37 . . NNP cord-006870-f5w6fw6q 4434 38 , , , cord-006870-f5w6fw6q 4434 39 2017 2017 CD cord-006870-f5w6fw6q 4434 40 ) ) -RRB- cord-006870-f5w6fw6q 4434 41 . . . cord-006870-f5w6fw6q 4435 1 We -PRON- PRP cord-006870-f5w6fw6q 4435 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 4435 3 that that IN cord-006870-f5w6fw6q 4435 4 IICAs iicas PRP cord-006870-f5w6fw6q 4435 5 acutely acutely RB cord-006870-f5w6fw6q 4435 6 following follow VBG cord-006870-f5w6fw6q 4435 7 TBI TBI NNP cord-006870-f5w6fw6q 4435 8 may may MD cord-006870-f5w6fw6q 4435 9 be be VB cord-006870-f5w6fw6q 4435 10 a a DT cord-006870-f5w6fw6q 4435 11 marker marker NN cord-006870-f5w6fw6q 4435 12 of of IN cord-006870-f5w6fw6q 4435 13 posttraumatic posttraumatic JJ cord-006870-f5w6fw6q 4435 14 epilepsy epilepsy NN cord-006870-f5w6fw6q 4435 15 risk risk NN cord-006870-f5w6fw6q 4435 16 . . . cord-006870-f5w6fw6q 4436 1 We -PRON- PRP cord-006870-f5w6fw6q 4436 2 evaluated evaluate VBD cord-006870-f5w6fw6q 4436 3 continuous continuous JJ cord-006870-f5w6fw6q 4436 4 EEG EEG NNP cord-006870-f5w6fw6q 4436 5 data datum NNS cord-006870-f5w6fw6q 4436 6 from from IN cord-006870-f5w6fw6q 4436 7 moderate moderate JJ cord-006870-f5w6fw6q 4436 8 to to IN cord-006870-f5w6fw6q 4436 9 severe severe JJ cord-006870-f5w6fw6q 4436 10 TBI TBI NNP cord-006870-f5w6fw6q 4436 11 patients patient NNS cord-006870-f5w6fw6q 4436 12 who who WP cord-006870-f5w6fw6q 4436 13 did do VBD cord-006870-f5w6fw6q 4436 14 and and CC cord-006870-f5w6fw6q 4436 15 did do VBD cord-006870-f5w6fw6q 4436 16 not not RB cord-006870-f5w6fw6q 4436 17 develop develop VB cord-006870-f5w6fw6q 4436 18 PTE PTE NNP cord-006870-f5w6fw6q 4436 19 , , , cord-006870-f5w6fw6q 4436 20 ( ( -LRB- cord-006870-f5w6fw6q 4436 21 any any DT cord-006870-f5w6fw6q 4436 22 seizure seizure NN cord-006870-f5w6fw6q 4436 23 2 2 CD cord-006870-f5w6fw6q 4436 24 - - SYM cord-006870-f5w6fw6q 4436 25 12 12 CD cord-006870-f5w6fw6q 4436 26 months month NNS cord-006870-f5w6fw6q 4436 27 post post JJ cord-006870-f5w6fw6q 4436 28 - - JJ cord-006870-f5w6fw6q 4436 29 TBI tbi NN cord-006870-f5w6fw6q 4436 30 ; ; : cord-006870-f5w6fw6q 4436 31 n=50 n=50 NN cord-006870-f5w6fw6q 4436 32 ) ) -RRB- cord-006870-f5w6fw6q 4436 33 . . . cord-006870-f5w6fw6q 4437 1 Seizures seizure NNS cord-006870-f5w6fw6q 4438 1 < < XX cord-006870-f5w6fw6q 4439 1 1month 1month NNP cord-006870-f5w6fw6q 4440 1 post post NNP cord-006870-f5w6fw6q 4440 2 - - NNP cord-006870-f5w6fw6q 4440 3 TBI TBI NNP cord-006870-f5w6fw6q 4440 4 were be VBD cord-006870-f5w6fw6q 4440 5 classified classify VBN cord-006870-f5w6fw6q 4440 6 as as IN cord-006870-f5w6fw6q 4440 7 symptomatic symptomatic JJ cord-006870-f5w6fw6q 4440 8 , , , cord-006870-f5w6fw6q 4440 9 not not RB cord-006870-f5w6fw6q 4440 10 PTE PTE NNP cord-006870-f5w6fw6q 4440 11 . . . cord-006870-f5w6fw6q 4441 1 Conventional conventional JJ cord-006870-f5w6fw6q 4441 2 10 10 CD cord-006870-f5w6fw6q 4441 3 - - SYM cord-006870-f5w6fw6q 4441 4 20 20 CD cord-006870-f5w6fw6q 4441 5 scalp scalp NN cord-006870-f5w6fw6q 4441 6 electrode electrode NN cord-006870-f5w6fw6q 4441 7 placement placement NN cord-006870-f5w6fw6q 4441 8 was be VBD cord-006870-f5w6fw6q 4441 9 used use VBN cord-006870-f5w6fw6q 4441 10 and and CC cord-006870-f5w6fw6q 4441 11 EEGs eeg NNS cord-006870-f5w6fw6q 4441 12 were be VBD cord-006870-f5w6fw6q 4441 13 reviewed review VBN cord-006870-f5w6fw6q 4441 14 by by IN cord-006870-f5w6fw6q 4441 15 standard standard JJ cord-006870-f5w6fw6q 4441 16 visual visual JJ cord-006870-f5w6fw6q 4441 17 analysis analysis NN cord-006870-f5w6fw6q 4441 18 , , , cord-006870-f5w6fw6q 4441 19 by by IN cord-006870-f5w6fw6q 4441 20 the the DT cord-006870-f5w6fw6q 4441 21 MGH MGH NNP cord-006870-f5w6fw6q 4441 22 neurophysiology neurophysiology NN cord-006870-f5w6fw6q 4441 23 service service NN cord-006870-f5w6fw6q 4441 24 . . . cord-006870-f5w6fw6q 4442 1 Daily Daily NNP cord-006870-f5w6fw6q 4442 2 EEG EEG NNP cord-006870-f5w6fw6q 4442 3 reports report NNS cord-006870-f5w6fw6q 4442 4 were be VBD cord-006870-f5w6fw6q 4442 5 scored score VBN cord-006870-f5w6fw6q 4442 6 for for IN cord-006870-f5w6fw6q 4442 7 the the DT cord-006870-f5w6fw6q 4442 8 presence presence NN cord-006870-f5w6fw6q 4442 9 of of IN cord-006870-f5w6fw6q 4442 10 IICAs iicas PRP cord-006870-f5w6fw6q 4442 11 and and CC cord-006870-f5w6fw6q 4442 12 seizures seizure NNS cord-006870-f5w6fw6q 4442 13 . . . cord-006870-f5w6fw6q 4443 1 Demographic demographic JJ cord-006870-f5w6fw6q 4443 2 data datum NNS cord-006870-f5w6fw6q 4443 3 including include VBG cord-006870-f5w6fw6q 4443 4 gender gender NN cord-006870-f5w6fw6q 4443 5 , , , cord-006870-f5w6fw6q 4443 6 age age NN cord-006870-f5w6fw6q 4443 7 , , , cord-006870-f5w6fw6q 4443 8 TBI tbi NN cord-006870-f5w6fw6q 4443 9 severity severity NN cord-006870-f5w6fw6q 4443 10 and and CC cord-006870-f5w6fw6q 4443 11 type type NN cord-006870-f5w6fw6q 4443 12 of of IN cord-006870-f5w6fw6q 4443 13 brain brain NN cord-006870-f5w6fw6q 4443 14 injury injury NN cord-006870-f5w6fw6q 4443 15 were be VBD cord-006870-f5w6fw6q 4443 16 recorded record VBN cord-006870-f5w6fw6q 4443 17 . . . cord-006870-f5w6fw6q 4444 1 Univariate univariate JJ cord-006870-f5w6fw6q 4444 2 and and CC cord-006870-f5w6fw6q 4444 3 multivariate multivariate JJ cord-006870-f5w6fw6q 4444 4 regression regression NN cord-006870-f5w6fw6q 4444 5 analyses analysis NNS cord-006870-f5w6fw6q 4444 6 were be VBD cord-006870-f5w6fw6q 4444 7 performed perform VBN cord-006870-f5w6fw6q 4444 8 to to TO cord-006870-f5w6fw6q 4444 9 determine determine VB cord-006870-f5w6fw6q 4444 10 which which WDT cord-006870-f5w6fw6q 4444 11 IICA IICA NNP cord-006870-f5w6fw6q 4444 12 and and CC cord-006870-f5w6fw6q 4444 13 demographic demographic JJ cord-006870-f5w6fw6q 4444 14 features feature NNS cord-006870-f5w6fw6q 4444 15 correlated correlate VBN cord-006870-f5w6fw6q 4444 16 with with IN cord-006870-f5w6fw6q 4444 17 PTE PTE NNP cord-006870-f5w6fw6q 4444 18 . . . cord-006870-f5w6fw6q 4445 1 GCS GCS NNP cord-006870-f5w6fw6q 4445 2 ( ( -LRB- cord-006870-f5w6fw6q 4445 3 p=0.02 p=0.02 NNP cord-006870-f5w6fw6q 4445 4 ) ) -RRB- cord-006870-f5w6fw6q 4445 5 and and CC cord-006870-f5w6fw6q 4445 6 TBI TBI NNP cord-006870-f5w6fw6q 4445 7 severity severity NN cord-006870-f5w6fw6q 4445 8 ( ( -LRB- cord-006870-f5w6fw6q 4445 9 p=0.02 p=0.02 NN cord-006870-f5w6fw6q 4445 10 ) ) -RRB- cord-006870-f5w6fw6q 4445 11 were be VBD cord-006870-f5w6fw6q 4445 12 significantly significantly RB cord-006870-f5w6fw6q 4445 13 associated associate VBN cord-006870-f5w6fw6q 4445 14 with with IN cord-006870-f5w6fw6q 4445 15 PTE PTE NNP cord-006870-f5w6fw6q 4445 16 , , , cord-006870-f5w6fw6q 4445 17 as as IN cord-006870-f5w6fw6q 4445 18 expected expect VBN cord-006870-f5w6fw6q 4445 19 . . . cord-006870-f5w6fw6q 4446 1 Seizures seizure NNS cord-006870-f5w6fw6q 4446 2 ( ( -LRB- cord-006870-f5w6fw6q 4446 3 p=0.002 p=0.002 NNP cord-006870-f5w6fw6q 4446 4 ) ) -RRB- cord-006870-f5w6fw6q 4446 5 , , , cord-006870-f5w6fw6q 4446 6 epileptiform epileptiform NNP cord-006870-f5w6fw6q 4446 7 discharges discharge NNS cord-006870-f5w6fw6q 4446 8 ( ( -LRB- cord-006870-f5w6fw6q 4446 9 p=0.0003 p=0.0003 NNP cord-006870-f5w6fw6q 4446 10 ) ) -RRB- cord-006870-f5w6fw6q 4446 11 , , , cord-006870-f5w6fw6q 4446 12 generalized generalize VBD cord-006870-f5w6fw6q 4446 13 periodic periodic JJ cord-006870-f5w6fw6q 4446 14 discharges discharge NNS cord-006870-f5w6fw6q 4446 15 ( ( -LRB- cord-006870-f5w6fw6q 4446 16 0.0003 0.0003 CD cord-006870-f5w6fw6q 4446 17 ) ) -RRB- cord-006870-f5w6fw6q 4446 18 and and CC cord-006870-f5w6fw6q 4446 19 lateralized lateralized JJ cord-006870-f5w6fw6q 4446 20 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4446 21 delta delta NN cord-006870-f5w6fw6q 4446 22 activity activity NN cord-006870-f5w6fw6q 4446 23 ( ( -LRB- cord-006870-f5w6fw6q 4446 24 p=0.04 p=0.04 NNP cord-006870-f5w6fw6q 4446 25 ) ) -RRB- cord-006870-f5w6fw6q 4446 26 independently independently RB cord-006870-f5w6fw6q 4446 27 predicted predict VBD cord-006870-f5w6fw6q 4446 28 risk risk NN cord-006870-f5w6fw6q 4446 29 for for IN cord-006870-f5w6fw6q 4446 30 post post JJ cord-006870-f5w6fw6q 4446 31 - - JJ cord-006870-f5w6fw6q 4446 32 traumatic traumatic JJ cord-006870-f5w6fw6q 4446 33 epilepsy epilepsy NN cord-006870-f5w6fw6q 4446 34 . . . cord-006870-f5w6fw6q 4447 1 Epileptiform Epileptiform NNP cord-006870-f5w6fw6q 4447 2 discharges discharge NNS cord-006870-f5w6fw6q 4447 3 , , , cord-006870-f5w6fw6q 4447 4 in in IN cord-006870-f5w6fw6q 4447 5 particular particular JJ cord-006870-f5w6fw6q 4447 6 , , , cord-006870-f5w6fw6q 4447 7 were be VBD cord-006870-f5w6fw6q 4447 8 more more RBR cord-006870-f5w6fw6q 4447 9 prevalent prevalent JJ cord-006870-f5w6fw6q 4447 10 acutely acutely RB cord-006870-f5w6fw6q 4447 11 post post JJ cord-006870-f5w6fw6q 4447 12 - - JJ cord-006870-f5w6fw6q 4447 13 TBI TBI NNP cord-006870-f5w6fw6q 4447 14 in in IN cord-006870-f5w6fw6q 4447 15 PTE PTE NNP cord-006870-f5w6fw6q 4447 16 patients patient NNS cord-006870-f5w6fw6q 4447 17 . . . cord-006870-f5w6fw6q 4448 1 Increased increase VBN cord-006870-f5w6fw6q 4448 2 IICA iica JJ cord-006870-f5w6fw6q 4448 3 prevalence prevalence NN cord-006870-f5w6fw6q 4448 4 is be VBZ cord-006870-f5w6fw6q 4448 5 significantly significantly RB cord-006870-f5w6fw6q 4448 6 associated associate VBN cord-006870-f5w6fw6q 4448 7 with with IN cord-006870-f5w6fw6q 4448 8 PTE PTE NNP cord-006870-f5w6fw6q 4448 9 and and CC cord-006870-f5w6fw6q 4448 10 may may MD cord-006870-f5w6fw6q 4448 11 be be VB cord-006870-f5w6fw6q 4448 12 a a DT cord-006870-f5w6fw6q 4448 13 predictive predictive JJ cord-006870-f5w6fw6q 4448 14 marker marker NN cord-006870-f5w6fw6q 4448 15 for for IN cord-006870-f5w6fw6q 4448 16 identifying identify VBG cord-006870-f5w6fw6q 4448 17 patients patient NNS cord-006870-f5w6fw6q 4448 18 who who WP cord-006870-f5w6fw6q 4448 19 may may MD cord-006870-f5w6fw6q 4448 20 benefit benefit VB cord-006870-f5w6fw6q 4448 21 from from IN cord-006870-f5w6fw6q 4448 22 anti anti JJ cord-006870-f5w6fw6q 4448 23 - - JJ cord-006870-f5w6fw6q 4448 24 epileptogenesis epileptogenesis JJ cord-006870-f5w6fw6q 4448 25 trials trial NNS cord-006870-f5w6fw6q 4448 26 . . . cord-006870-f5w6fw6q 4449 1 Rapidly rapidly RB cord-006870-f5w6fw6q 4449 2 obtaining obtain VBG cord-006870-f5w6fw6q 4449 3 EEG EEG NNP cord-006870-f5w6fw6q 4449 4 signals signal NNS cord-006870-f5w6fw6q 4449 5 in in IN cord-006870-f5w6fw6q 4449 6 the the DT cord-006870-f5w6fw6q 4449 7 ED ED NNP cord-006870-f5w6fw6q 4449 8 and and CC cord-006870-f5w6fw6q 4449 9 ICU ICU NNP cord-006870-f5w6fw6q 4449 10 for for IN cord-006870-f5w6fw6q 4449 11 at at IN cord-006870-f5w6fw6q 4449 12 - - HYPH cord-006870-f5w6fw6q 4449 13 risk risk NN cord-006870-f5w6fw6q 4449 14 patients patient NNS cord-006870-f5w6fw6q 4449 15 can can MD cord-006870-f5w6fw6q 4449 16 enhance enhance VB cord-006870-f5w6fw6q 4449 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 4449 18 accuracy accuracy NN cord-006870-f5w6fw6q 4449 19 and and CC cord-006870-f5w6fw6q 4449 20 speed speed NN cord-006870-f5w6fw6q 4449 21 , , , cord-006870-f5w6fw6q 4449 22 while while IN cord-006870-f5w6fw6q 4449 23 cutting cut VBG cord-006870-f5w6fw6q 4449 24 down down RP cord-006870-f5w6fw6q 4449 25 time time NN cord-006870-f5w6fw6q 4449 26 until until IN cord-006870-f5w6fw6q 4449 27 treatment treatment NN cord-006870-f5w6fw6q 4449 28 . . . cord-006870-f5w6fw6q 4450 1 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4450 2 Inc Inc NNP cord-006870-f5w6fw6q 4450 3 has have VBZ cord-006870-f5w6fw6q 4450 4 developed develop VBN cord-006870-f5w6fw6q 4450 5 a a DT cord-006870-f5w6fw6q 4450 6 portable portable JJ cord-006870-f5w6fw6q 4450 7 EEG EEG NNP cord-006870-f5w6fw6q 4450 8 data datum NNS cord-006870-f5w6fw6q 4450 9 recorder recorder NN cord-006870-f5w6fw6q 4450 10 and and CC cord-006870-f5w6fw6q 4450 11 electrode electrode NN cord-006870-f5w6fw6q 4450 12 headset headset NN cord-006870-f5w6fw6q 4450 13 with with IN cord-006870-f5w6fw6q 4450 14 rapid rapid JJ cord-006870-f5w6fw6q 4450 15 setup setup NN cord-006870-f5w6fw6q 4450 16 ( ( -LRB- cord-006870-f5w6fw6q 4450 17 ~ ~ NFP cord-006870-f5w6fw6q 4450 18 5 5 CD cord-006870-f5w6fw6q 4450 19 min min NN cord-006870-f5w6fw6q 4450 20 ) ) -RRB- cord-006870-f5w6fw6q 4450 21 technology technology NN cord-006870-f5w6fw6q 4450 22 without without IN cord-006870-f5w6fw6q 4450 23 any any DT cord-006870-f5w6fw6q 4450 24 EEG EEG NNP cord-006870-f5w6fw6q 4450 25 technician technician NN cord-006870-f5w6fw6q 4450 26 required require VBN cord-006870-f5w6fw6q 4450 27 to to TO cord-006870-f5w6fw6q 4450 28 overcome overcome VB cord-006870-f5w6fw6q 4450 29 the the DT cord-006870-f5w6fw6q 4450 30 inaccessibility inaccessibility NN cord-006870-f5w6fw6q 4450 31 of of IN cord-006870-f5w6fw6q 4450 32 EEG EEG NNP cord-006870-f5w6fw6q 4450 33 in in IN cord-006870-f5w6fw6q 4450 34 urgent urgent JJ cord-006870-f5w6fw6q 4450 35 situations situation NNS cord-006870-f5w6fw6q 4450 36 when when WRB cord-006870-f5w6fw6q 4450 37 seizures seizure NNS cord-006870-f5w6fw6q 4450 38 are be VBP cord-006870-f5w6fw6q 4450 39 suspected suspect VBN cord-006870-f5w6fw6q 4450 40 . . . cord-006870-f5w6fw6q 4451 1 The the DT cord-006870-f5w6fw6q 4451 2 purpose purpose NN cord-006870-f5w6fw6q 4451 3 of of IN cord-006870-f5w6fw6q 4451 4 this this DT cord-006870-f5w6fw6q 4451 5 study study NN cord-006870-f5w6fw6q 4451 6 is be VBZ cord-006870-f5w6fw6q 4451 7 to to TO cord-006870-f5w6fw6q 4451 8 evaluate evaluate VB cord-006870-f5w6fw6q 4451 9 the the DT cord-006870-f5w6fw6q 4451 10 signal signal JJ cord-006870-f5w6fw6q 4451 11 quality quality NN cord-006870-f5w6fw6q 4451 12 and and CC cord-006870-f5w6fw6q 4451 13 performance performance NN cord-006870-f5w6fw6q 4451 14 of of IN cord-006870-f5w6fw6q 4451 15 the the DT cord-006870-f5w6fw6q 4451 16 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4451 17 system system NN cord-006870-f5w6fw6q 4451 18 compared compare VBN cord-006870-f5w6fw6q 4451 19 to to IN cord-006870-f5w6fw6q 4451 20 a a DT cord-006870-f5w6fw6q 4451 21 reputable reputable JJ cord-006870-f5w6fw6q 4451 22 clinical clinical JJ cord-006870-f5w6fw6q 4451 23 EEG EEG NNP cord-006870-f5w6fw6q 4451 24 system system NN cord-006870-f5w6fw6q 4451 25 . . . cord-006870-f5w6fw6q 4452 1 We -PRON- PRP cord-006870-f5w6fw6q 4452 2 collected collect VBD cord-006870-f5w6fw6q 4452 3 EEG EEG NNP cord-006870-f5w6fw6q 4452 4 samples sample NNS cord-006870-f5w6fw6q 4452 5 in in IN cord-006870-f5w6fw6q 4452 6 the the DT cord-006870-f5w6fw6q 4452 7 laboratory laboratory NN cord-006870-f5w6fw6q 4452 8 and and CC cord-006870-f5w6fw6q 4452 9 at at IN cord-006870-f5w6fw6q 4452 10 Stanford Stanford NNP cord-006870-f5w6fw6q 4452 11 University University NNP cord-006870-f5w6fw6q 4452 12 Medical Medical NNP cord-006870-f5w6fw6q 4452 13 Center Center NNP cord-006870-f5w6fw6q 4452 14 . . . cord-006870-f5w6fw6q 4453 1 Laboratory laboratory NN cord-006870-f5w6fw6q 4453 2 collections collection NNS cord-006870-f5w6fw6q 4453 3 on on IN cord-006870-f5w6fw6q 4453 4 healthy healthy JJ cord-006870-f5w6fw6q 4453 5 volunteers volunteer NNS cord-006870-f5w6fw6q 4453 6 included include VBD cord-006870-f5w6fw6q 4453 7 simultaneous simultaneous JJ cord-006870-f5w6fw6q 4453 8 collection collection NN cord-006870-f5w6fw6q 4453 9 of of IN cord-006870-f5w6fw6q 4453 10 EEG EEG NNP cord-006870-f5w6fw6q 4453 11 using use VBG cord-006870-f5w6fw6q 4453 12 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4453 13 and and CC cord-006870-f5w6fw6q 4453 14 Nihon Nihon NNP cord-006870-f5w6fw6q 4453 15 Kohden Kohden NNP cord-006870-f5w6fw6q 4453 16 systems system NNS cord-006870-f5w6fw6q 4453 17 , , , cord-006870-f5w6fw6q 4453 18 and and CC cord-006870-f5w6fw6q 4453 19 a a DT cord-006870-f5w6fw6q 4453 20 split split NN cord-006870-f5w6fw6q 4453 21 - - HYPH cord-006870-f5w6fw6q 4453 22 signal signal NN cord-006870-f5w6fw6q 4453 23 that that WDT cord-006870-f5w6fw6q 4453 24 recorded record VBD cord-006870-f5w6fw6q 4453 25 EEG EEG NNP cord-006870-f5w6fw6q 4453 26 to to IN cord-006870-f5w6fw6q 4453 27 both both DT cord-006870-f5w6fw6q 4453 28 data datum NNS cord-006870-f5w6fw6q 4453 29 recorders recorder NNS cord-006870-f5w6fw6q 4453 30 from from IN cord-006870-f5w6fw6q 4453 31 the the DT cord-006870-f5w6fw6q 4453 32 same same JJ cord-006870-f5w6fw6q 4453 33 electrodes electrode NNS cord-006870-f5w6fw6q 4453 34 . . . cord-006870-f5w6fw6q 4454 1 In in IN cord-006870-f5w6fw6q 4454 2 the the DT cord-006870-f5w6fw6q 4454 3 ICU ICU NNP cord-006870-f5w6fw6q 4454 4 , , , cord-006870-f5w6fw6q 4454 5 EEG EEG NNP cord-006870-f5w6fw6q 4454 6 was be VBD cord-006870-f5w6fw6q 4454 7 recorded record VBN cord-006870-f5w6fw6q 4454 8 with with IN cord-006870-f5w6fw6q 4454 9 the the DT cord-006870-f5w6fw6q 4454 10 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4454 11 system system NN cord-006870-f5w6fw6q 4454 12 on on IN cord-006870-f5w6fw6q 4454 13 25 25 CD cord-006870-f5w6fw6q 4454 14 patients patient NNS cord-006870-f5w6fw6q 4454 15 and and CC cord-006870-f5w6fw6q 4454 16 subsequently subsequently RB cord-006870-f5w6fw6q 4454 17 with with IN cord-006870-f5w6fw6q 4454 18 the the DT cord-006870-f5w6fw6q 4454 19 clinical clinical JJ cord-006870-f5w6fw6q 4454 20 EEG EEG NNP cord-006870-f5w6fw6q 4454 21 system system NN cord-006870-f5w6fw6q 4454 22 . . . cord-006870-f5w6fw6q 4455 1 Data datum NNS cord-006870-f5w6fw6q 4455 2 was be VBD cord-006870-f5w6fw6q 4455 3 filtered filter VBN cord-006870-f5w6fw6q 4455 4 and and CC cord-006870-f5w6fw6q 4455 5 spectral spectral JJ cord-006870-f5w6fw6q 4455 6 densities density NNS cord-006870-f5w6fw6q 4455 7 , , , cord-006870-f5w6fw6q 4455 8 Mean Mean NNP cord-006870-f5w6fw6q 4455 9 Frequency Frequency NNP cord-006870-f5w6fw6q 4455 10 ( ( -LRB- cord-006870-f5w6fw6q 4455 11 MF MF NNP cord-006870-f5w6fw6q 4455 12 ) ) -RRB- cord-006870-f5w6fw6q 4455 13 , , , cord-006870-f5w6fw6q 4455 14 Spectral Spectral NNP cord-006870-f5w6fw6q 4455 15 Entropy Entropy NNP cord-006870-f5w6fw6q 4455 16 ( ( -LRB- cord-006870-f5w6fw6q 4455 17 SE SE NNP cord-006870-f5w6fw6q 4455 18 ) ) -RRB- cord-006870-f5w6fw6q 4455 19 , , , cord-006870-f5w6fw6q 4455 20 and and CC cord-006870-f5w6fw6q 4455 21 75 75 CD cord-006870-f5w6fw6q 4455 22 % % NN cord-006870-f5w6fw6q 4455 23 Spectral spectral JJ cord-006870-f5w6fw6q 4455 24 Edge Edge NNP cord-006870-f5w6fw6q 4455 25 Frequency Frequency NNP cord-006870-f5w6fw6q 4455 26 ( ( -LRB- cord-006870-f5w6fw6q 4455 27 SEF75 SEF75 NNP cord-006870-f5w6fw6q 4455 28 ) ) -RRB- cord-006870-f5w6fw6q 4455 29 were be VBD cord-006870-f5w6fw6q 4455 30 computed compute VBN cord-006870-f5w6fw6q 4455 31 . . . cord-006870-f5w6fw6q 4456 1 In in IN cord-006870-f5w6fw6q 4456 2 the the DT cord-006870-f5w6fw6q 4456 3 split split JJ cord-006870-f5w6fw6q 4456 4 - - HYPH cord-006870-f5w6fw6q 4456 5 signal signal NN cord-006870-f5w6fw6q 4456 6 test test NN cord-006870-f5w6fw6q 4456 7 , , , cord-006870-f5w6fw6q 4456 8 the the DT cord-006870-f5w6fw6q 4456 9 waveforms waveform NNS cord-006870-f5w6fw6q 4456 10 consistently consistently RB cord-006870-f5w6fw6q 4456 11 appeared appear VBD cord-006870-f5w6fw6q 4456 12 similar similar JJ cord-006870-f5w6fw6q 4456 13 by by IN cord-006870-f5w6fw6q 4456 14 visual visual JJ cord-006870-f5w6fw6q 4456 15 inspection inspection NN cord-006870-f5w6fw6q 4456 16 . . . cord-006870-f5w6fw6q 4457 1 The the DT cord-006870-f5w6fw6q 4457 2 analysis analysis NN cord-006870-f5w6fw6q 4457 3 of of IN cord-006870-f5w6fw6q 4457 4 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4457 5 data datum NNS cord-006870-f5w6fw6q 4457 6 revealed reveal VBD cord-006870-f5w6fw6q 4457 7 ( ( -LRB- cord-006870-f5w6fw6q 4457 8 MF MF NNP cord-006870-f5w6fw6q 4457 9 = = : cord-006870-f5w6fw6q 4457 10 22.46 22.46 CD cord-006870-f5w6fw6q 4457 11 Hz Hz NNP cord-006870-f5w6fw6q 4457 12 , , , cord-006870-f5w6fw6q 4457 13 SE= SE= NNP cord-006870-f5w6fw6q 4457 14 8.51 8.51 CD cord-006870-f5w6fw6q 4457 15 , , , cord-006870-f5w6fw6q 4457 16 SEF75 SEF75 NNP cord-006870-f5w6fw6q 4457 17 = = SYM cord-006870-f5w6fw6q 4457 18 21.56 21.56 CD cord-006870-f5w6fw6q 4457 19 ) ) -RRB- cord-006870-f5w6fw6q 4457 20 similar similar JJ cord-006870-f5w6fw6q 4457 21 to to IN cord-006870-f5w6fw6q 4457 22 the the DT cord-006870-f5w6fw6q 4457 23 commercial commercial JJ cord-006870-f5w6fw6q 4457 24 system system NN cord-006870-f5w6fw6q 4457 25 ( ( -LRB- cord-006870-f5w6fw6q 4457 26 MF mf NN cord-006870-f5w6fw6q 4457 27 = = SYM cord-006870-f5w6fw6q 4457 28 22.86 22.86 CD cord-006870-f5w6fw6q 4457 29 Hz Hz NNP cord-006870-f5w6fw6q 4457 30 , , , cord-006870-f5w6fw6q 4457 31 SE SE NNP cord-006870-f5w6fw6q 4457 32 = = SYM cord-006870-f5w6fw6q 4457 33 8.52 8.52 CD cord-006870-f5w6fw6q 4457 34 , , , cord-006870-f5w6fw6q 4457 35 SEF75 SEF75 NNP cord-006870-f5w6fw6q 4457 36 = = SYM cord-006870-f5w6fw6q 4457 37 21.58 21.58 CD cord-006870-f5w6fw6q 4457 38 ) ) -RRB- cord-006870-f5w6fw6q 4457 39 . . . cord-006870-f5w6fw6q 4458 1 In in IN cord-006870-f5w6fw6q 4458 2 the the DT cord-006870-f5w6fw6q 4458 3 simultaneous simultaneous JJ cord-006870-f5w6fw6q 4458 4 test test NN cord-006870-f5w6fw6q 4458 5 , , , cord-006870-f5w6fw6q 4458 6 the the DT cord-006870-f5w6fw6q 4458 7 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4458 8 system system NN cord-006870-f5w6fw6q 4458 9 produced produce VBD cord-006870-f5w6fw6q 4458 10 ( ( -LRB- cord-006870-f5w6fw6q 4458 11 MF mf NN cord-006870-f5w6fw6q 4458 12 = = SYM cord-006870-f5w6fw6q 4458 13 14.3 14.3 CD cord-006870-f5w6fw6q 4458 14 Hz Hz NNP cord-006870-f5w6fw6q 4458 15 , , , cord-006870-f5w6fw6q 4458 16 SE SE NNP cord-006870-f5w6fw6q 4458 17 = = SYM cord-006870-f5w6fw6q 4458 18 8.4 8.4 CD cord-006870-f5w6fw6q 4458 19 , , , cord-006870-f5w6fw6q 4458 20 SEF75 sef75 NN cord-006870-f5w6fw6q 4458 21 = = SYM cord-006870-f5w6fw6q 4458 22 17.36 17.36 CD cord-006870-f5w6fw6q 4458 23 ) ) -RRB- cord-006870-f5w6fw6q 4459 1 similar similar JJ cord-006870-f5w6fw6q 4459 2 to to IN cord-006870-f5w6fw6q 4459 3 the the DT cord-006870-f5w6fw6q 4459 4 commercial commercial JJ cord-006870-f5w6fw6q 4459 5 system system NN cord-006870-f5w6fw6q 4459 6 ( ( -LRB- cord-006870-f5w6fw6q 4459 7 MF mf NN cord-006870-f5w6fw6q 4459 8 = = SYM cord-006870-f5w6fw6q 4459 9 15.5 15.5 CD cord-006870-f5w6fw6q 4459 10 Hz Hz NNP cord-006870-f5w6fw6q 4459 11 , , , cord-006870-f5w6fw6q 4459 12 SE SE NNP cord-006870-f5w6fw6q 4459 13 = = SYM cord-006870-f5w6fw6q 4459 14 8.58 8.58 CD cord-006870-f5w6fw6q 4459 15 , , , cord-006870-f5w6fw6q 4459 16 SEF75 SEF75 NNP cord-006870-f5w6fw6q 4459 17 = = SYM cord-006870-f5w6fw6q 4459 18 18.84 18.84 CD cord-006870-f5w6fw6q 4459 19 ) ) -RRB- cord-006870-f5w6fw6q 4459 20 . . . cord-006870-f5w6fw6q 4460 1 In in IN cord-006870-f5w6fw6q 4460 2 the the DT cord-006870-f5w6fw6q 4460 3 clinical clinical JJ cord-006870-f5w6fw6q 4460 4 setting setting NN cord-006870-f5w6fw6q 4460 5 , , , cord-006870-f5w6fw6q 4460 6 the the DT cord-006870-f5w6fw6q 4460 7 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4460 8 system system NN cord-006870-f5w6fw6q 4460 9 showed show VBD cord-006870-f5w6fw6q 4460 10 spectral spectral JJ cord-006870-f5w6fw6q 4460 11 density density NN cord-006870-f5w6fw6q 4460 12 distributions distribution NNS cord-006870-f5w6fw6q 4460 13 comparable comparable JJ cord-006870-f5w6fw6q 4460 14 with with IN cord-006870-f5w6fw6q 4460 15 the the DT cord-006870-f5w6fw6q 4460 16 commercial commercial JJ cord-006870-f5w6fw6q 4460 17 system system NN cord-006870-f5w6fw6q 4460 18 . . . cord-006870-f5w6fw6q 4461 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4461 2 results result NNS cord-006870-f5w6fw6q 4461 3 indicate indicate VBP cord-006870-f5w6fw6q 4461 4 that that IN cord-006870-f5w6fw6q 4461 5 the the DT cord-006870-f5w6fw6q 4461 6 signal signal JJ cord-006870-f5w6fw6q 4461 7 quality quality NN cord-006870-f5w6fw6q 4461 8 of of IN cord-006870-f5w6fw6q 4461 9 the the DT cord-006870-f5w6fw6q 4461 10 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4461 11 system system NN cord-006870-f5w6fw6q 4461 12 is be VBZ cord-006870-f5w6fw6q 4461 13 similar similar JJ cord-006870-f5w6fw6q 4461 14 to to IN cord-006870-f5w6fw6q 4461 15 a a DT cord-006870-f5w6fw6q 4461 16 commercially commercially RB cord-006870-f5w6fw6q 4461 17 available available JJ cord-006870-f5w6fw6q 4461 18 EEG EEG NNP cord-006870-f5w6fw6q 4461 19 used use VBN cord-006870-f5w6fw6q 4461 20 widely widely RB cord-006870-f5w6fw6q 4461 21 in in IN cord-006870-f5w6fw6q 4461 22 the the DT cord-006870-f5w6fw6q 4461 23 clinical clinical JJ cord-006870-f5w6fw6q 4461 24 setting setting NN cord-006870-f5w6fw6q 4461 25 , , , cord-006870-f5w6fw6q 4461 26 while while IN cord-006870-f5w6fw6q 4461 27 requiring require VBG cord-006870-f5w6fw6q 4461 28 less less JJR cord-006870-f5w6fw6q 4461 29 setup setup NN cord-006870-f5w6fw6q 4461 30 time time NN cord-006870-f5w6fw6q 4461 31 and and CC cord-006870-f5w6fw6q 4461 32 allowing allow VBG cord-006870-f5w6fw6q 4461 33 more more JJR cord-006870-f5w6fw6q 4461 34 portability portability NN cord-006870-f5w6fw6q 4461 35 . . . cord-006870-f5w6fw6q 4462 1 Status status NN cord-006870-f5w6fw6q 4462 2 epilepticus epilepticus NN cord-006870-f5w6fw6q 4462 3 ( ( -LRB- cord-006870-f5w6fw6q 4462 4 SE SE NNP cord-006870-f5w6fw6q 4462 5 ) ) -RRB- cord-006870-f5w6fw6q 4462 6 is be VBZ cord-006870-f5w6fw6q 4462 7 a a DT cord-006870-f5w6fw6q 4462 8 life life NN cord-006870-f5w6fw6q 4462 9 - - HYPH cord-006870-f5w6fw6q 4462 10 threatening threaten VBG cord-006870-f5w6fw6q 4462 11 condition condition NN cord-006870-f5w6fw6q 4462 12 characterized characterize VBN cord-006870-f5w6fw6q 4462 13 by by IN cord-006870-f5w6fw6q 4462 14 prolonged prolonged JJ cord-006870-f5w6fw6q 4462 15 seizures seizure NNS cord-006870-f5w6fw6q 4462 16 without without IN cord-006870-f5w6fw6q 4462 17 regaining regain VBG cord-006870-f5w6fw6q 4462 18 consciousness consciousness NN cord-006870-f5w6fw6q 4462 19 between between IN cord-006870-f5w6fw6q 4462 20 seizure seizure NN cord-006870-f5w6fw6q 4462 21 events event NNS cord-006870-f5w6fw6q 4462 22 . . . cord-006870-f5w6fw6q 4463 1 When when WRB cord-006870-f5w6fw6q 4463 2 SE SE NNP cord-006870-f5w6fw6q 4463 3 continues continue VBZ cord-006870-f5w6fw6q 4463 4 or or CC cord-006870-f5w6fw6q 4463 5 recurs recur VBZ cord-006870-f5w6fw6q 4463 6 24 24 CD cord-006870-f5w6fw6q 4463 7 hours hour NNS cord-006870-f5w6fw6q 4463 8 or or CC cord-006870-f5w6fw6q 4463 9 more more JJR cord-006870-f5w6fw6q 4463 10 after after IN cord-006870-f5w6fw6q 4463 11 treatment treatment NN cord-006870-f5w6fw6q 4463 12 with with IN cord-006870-f5w6fw6q 4463 13 third third JJ cord-006870-f5w6fw6q 4463 14 line line NN cord-006870-f5w6fw6q 4463 15 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4463 16 agents agent NNS cord-006870-f5w6fw6q 4463 17 , , , cord-006870-f5w6fw6q 4463 18 it -PRON- PRP cord-006870-f5w6fw6q 4463 19 is be VBZ cord-006870-f5w6fw6q 4463 20 considered consider VBN cord-006870-f5w6fw6q 4463 21 super super JJ cord-006870-f5w6fw6q 4463 22 - - JJ cord-006870-f5w6fw6q 4463 23 refractory refractory JJ cord-006870-f5w6fw6q 4463 24 SE se NN cord-006870-f5w6fw6q 4463 25 ( ( -LRB- cord-006870-f5w6fw6q 4463 26 SRSE SRSE NNP cord-006870-f5w6fw6q 4463 27 ) ) -RRB- cord-006870-f5w6fw6q 4463 28 . . . cord-006870-f5w6fw6q 4464 1 There there EX cord-006870-f5w6fw6q 4464 2 are be VBP cord-006870-f5w6fw6q 4464 3 few few JJ cord-006870-f5w6fw6q 4464 4 population population NN cord-006870-f5w6fw6q 4464 5 - - HYPH cord-006870-f5w6fw6q 4464 6 based base VBN cord-006870-f5w6fw6q 4464 7 studies study NNS cord-006870-f5w6fw6q 4464 8 on on IN cord-006870-f5w6fw6q 4464 9 the the DT cord-006870-f5w6fw6q 4464 10 descriptive descriptive JJ cord-006870-f5w6fw6q 4464 11 epidemiology epidemiology NN cord-006870-f5w6fw6q 4464 12 of of IN cord-006870-f5w6fw6q 4464 13 SRSE SRSE NNP cord-006870-f5w6fw6q 4464 14 at at IN cord-006870-f5w6fw6q 4464 15 a a DT cord-006870-f5w6fw6q 4464 16 national national JJ cord-006870-f5w6fw6q 4464 17 level level NN cord-006870-f5w6fw6q 4464 18 . . . cord-006870-f5w6fw6q 4465 1 The the DT cord-006870-f5w6fw6q 4465 2 objective objective NN cord-006870-f5w6fw6q 4465 3 was be VBD cord-006870-f5w6fw6q 4465 4 to to TO cord-006870-f5w6fw6q 4465 5 estimate estimate VB cord-006870-f5w6fw6q 4465 6 the the DT cord-006870-f5w6fw6q 4465 7 incidence incidence NN cord-006870-f5w6fw6q 4465 8 of of IN cord-006870-f5w6fw6q 4465 9 SRSE SRSE NNP cord-006870-f5w6fw6q 4465 10 in in IN cord-006870-f5w6fw6q 4465 11 Canada Canada NNP cord-006870-f5w6fw6q 4465 12 in in IN cord-006870-f5w6fw6q 4465 13 2010 2010 CD cord-006870-f5w6fw6q 4465 14 - - SYM cord-006870-f5w6fw6q 4465 15 2012 2012 CD cord-006870-f5w6fw6q 4465 16 . . . cord-006870-f5w6fw6q 4466 1 We -PRON- PRP cord-006870-f5w6fw6q 4466 2 analyzed analyze VBD cord-006870-f5w6fw6q 4466 3 standardized standardized JJ cord-006870-f5w6fw6q 4466 4 national national JJ cord-006870-f5w6fw6q 4466 5 administrative administrative JJ cord-006870-f5w6fw6q 4466 6 record record NN cord-006870-f5w6fw6q 4466 7 - - HYPH cord-006870-f5w6fw6q 4466 8 level level NN cord-006870-f5w6fw6q 4466 9 data datum NNS cord-006870-f5w6fw6q 4466 10 covering cover VBG cord-006870-f5w6fw6q 4466 11 all all DT cord-006870-f5w6fw6q 4466 12 provinces province NNS cord-006870-f5w6fw6q 4466 13 across across IN cord-006870-f5w6fw6q 4466 14 Canada Canada NNP cord-006870-f5w6fw6q 4466 15 as as IN cord-006870-f5w6fw6q 4466 16 provided provide VBN cord-006870-f5w6fw6q 4466 17 by by IN cord-006870-f5w6fw6q 4466 18 the the DT cord-006870-f5w6fw6q 4466 19 Canadian Canadian NNP cord-006870-f5w6fw6q 4466 20 Institute Institute NNP cord-006870-f5w6fw6q 4466 21 for for IN cord-006870-f5w6fw6q 4466 22 Health Health NNP cord-006870-f5w6fw6q 4466 23 Information Information NNP cord-006870-f5w6fw6q 4466 24 . . . cord-006870-f5w6fw6q 4467 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4467 2 episodes episode NNS cord-006870-f5w6fw6q 4467 3 were be VBD cord-006870-f5w6fw6q 4467 4 classified classify VBN cord-006870-f5w6fw6q 4467 5 from from IN cord-006870-f5w6fw6q 4467 6 two two CD cord-006870-f5w6fw6q 4467 7 databases database NNS cord-006870-f5w6fw6q 4467 8 for for IN cord-006870-f5w6fw6q 4467 9 acute acute JJ cord-006870-f5w6fw6q 4467 10 care care NN cord-006870-f5w6fw6q 4467 11 admissions admission NNS cord-006870-f5w6fw6q 4467 12 ( ( -LRB- cord-006870-f5w6fw6q 4467 13 Discharge Discharge NNP cord-006870-f5w6fw6q 4467 14 Abstract Abstract NNP cord-006870-f5w6fw6q 4467 15 Database Database NNP cord-006870-f5w6fw6q 4467 16 ) ) -RRB- cord-006870-f5w6fw6q 4467 17 and and CC cord-006870-f5w6fw6q 4467 18 emergency emergency NN cord-006870-f5w6fw6q 4467 19 visits visit NNS cord-006870-f5w6fw6q 4467 20 ( ( -LRB- cord-006870-f5w6fw6q 4467 21 National National NNP cord-006870-f5w6fw6q 4467 22 Ambulatory Ambulatory NNP cord-006870-f5w6fw6q 4467 23 Care Care NNP cord-006870-f5w6fw6q 4467 24 Reporting Reporting NNP cord-006870-f5w6fw6q 4467 25 System System NNP cord-006870-f5w6fw6q 4467 26 ) ) -RRB- cord-006870-f5w6fw6q 4467 27 over over IN cord-006870-f5w6fw6q 4467 28 3 3 CD cord-006870-f5w6fw6q 4467 29 fiscal fiscal JJ cord-006870-f5w6fw6q 4467 30 years year NNS cord-006870-f5w6fw6q 4467 31 ( ( -LRB- cord-006870-f5w6fw6q 4467 32 2010/2011 2010/2011 CD cord-006870-f5w6fw6q 4467 33 to to IN cord-006870-f5w6fw6q 4467 34 2012/2013 2012/2013 CD cord-006870-f5w6fw6q 4467 35 ) ) -RRB- cord-006870-f5w6fw6q 4467 36 . . . cord-006870-f5w6fw6q 4468 1 Cases case NNS cord-006870-f5w6fw6q 4468 2 were be VBD cord-006870-f5w6fw6q 4468 3 identified identify VBN cord-006870-f5w6fw6q 4468 4 as as IN cord-006870-f5w6fw6q 4468 5 SRSE SRSE NNP cord-006870-f5w6fw6q 4468 6 using use VBG cord-006870-f5w6fw6q 4468 7 a a DT cord-006870-f5w6fw6q 4468 8 modification modification NN cord-006870-f5w6fw6q 4468 9 of of IN cord-006870-f5w6fw6q 4468 10 a a DT cord-006870-f5w6fw6q 4468 11 previously previously RB cord-006870-f5w6fw6q 4468 12 published publish VBN cord-006870-f5w6fw6q 4468 13 algorithm algorithm NN cord-006870-f5w6fw6q 4468 14 using use VBG cord-006870-f5w6fw6q 4468 15 ICD-10-CA ICD-10-CA NNP cord-006870-f5w6fw6q 4468 16 diagnostic diagnostic JJ cord-006870-f5w6fw6q 4468 17 codes code NNS cord-006870-f5w6fw6q 4468 18 for for IN cord-006870-f5w6fw6q 4468 19 epilepsy epilepsy NN cord-006870-f5w6fw6q 4468 20 ( ( -LRB- cord-006870-f5w6fw6q 4468 21 G40 G40 NNP cord-006870-f5w6fw6q 4468 22 ) ) -RRB- cord-006870-f5w6fw6q 4468 23 , , , cord-006870-f5w6fw6q 4468 24 status status NN cord-006870-f5w6fw6q 4468 25 epilepticus epilepticus NN cord-006870-f5w6fw6q 4468 26 ( ( -LRB- cord-006870-f5w6fw6q 4468 27 G41 G41 NNP cord-006870-f5w6fw6q 4468 28 ) ) -RRB- cord-006870-f5w6fw6q 4468 29 , , , cord-006870-f5w6fw6q 4468 30 or or CC cord-006870-f5w6fw6q 4468 31 convulsions convulsion NNS cord-006870-f5w6fw6q 4468 32 ( ( -LRB- cord-006870-f5w6fw6q 4468 33 R56 R56 NNP cord-006870-f5w6fw6q 4468 34 ) ) -RRB- cord-006870-f5w6fw6q 4468 35 plus plus CC cord-006870-f5w6fw6q 4468 36 an an DT cord-006870-f5w6fw6q 4468 37 intensive intensive JJ cord-006870-f5w6fw6q 4468 38 care care NN cord-006870-f5w6fw6q 4468 39 unit unit NN cord-006870-f5w6fw6q 4468 40 stay stay NN cord-006870-f5w6fw6q 4468 41 of of IN cord-006870-f5w6fw6q 4468 42 2 2 CD cord-006870-f5w6fw6q 4468 43 days day NNS cord-006870-f5w6fw6q 4468 44 or or CC cord-006870-f5w6fw6q 4468 45 more more JJR cord-006870-f5w6fw6q 4468 46 with with IN cord-006870-f5w6fw6q 4468 47 mechanical mechanical JJ cord-006870-f5w6fw6q 4468 48 invasive invasive JJ cord-006870-f5w6fw6q 4468 49 ventilation ventilation NN cord-006870-f5w6fw6q 4468 50 . . . cord-006870-f5w6fw6q 4469 1 Using use VBG cord-006870-f5w6fw6q 4469 2 our -PRON- PRP$ cord-006870-f5w6fw6q 4469 3 algorithm algorithm NN cord-006870-f5w6fw6q 4469 4 , , , cord-006870-f5w6fw6q 4469 5 from from IN cord-006870-f5w6fw6q 4469 6 2010 2010 CD cord-006870-f5w6fw6q 4469 7 - - SYM cord-006870-f5w6fw6q 4469 8 2012 2012 CD cord-006870-f5w6fw6q 4469 9 , , , cord-006870-f5w6fw6q 4469 10 the the DT cord-006870-f5w6fw6q 4469 11 mean mean JJ cord-006870-f5w6fw6q 4469 12 annual annual JJ cord-006870-f5w6fw6q 4469 13 number number NN cord-006870-f5w6fw6q 4469 14 of of IN cord-006870-f5w6fw6q 4469 15 cases case NNS cord-006870-f5w6fw6q 4469 16 classified classify VBN cord-006870-f5w6fw6q 4469 17 as as IN cord-006870-f5w6fw6q 4469 18 SRSE SRSE NNP cord-006870-f5w6fw6q 4469 19 was be VBD cord-006870-f5w6fw6q 4469 20 3,427 3,427 CD cord-006870-f5w6fw6q 4470 1 ( ( -LRB- cord-006870-f5w6fw6q 4470 2 9.98/100,000 9.98/100,000 CD cord-006870-f5w6fw6q 4470 3 persons person NNS cord-006870-f5w6fw6q 4470 4 per per IN cord-006870-f5w6fw6q 4470 5 year year NN cord-006870-f5w6fw6q 4470 6 ) ) -RRB- cord-006870-f5w6fw6q 4470 7 . . . cord-006870-f5w6fw6q 4471 1 The the DT cord-006870-f5w6fw6q 4471 2 annual annual JJ cord-006870-f5w6fw6q 4471 3 incidence incidence NN cord-006870-f5w6fw6q 4471 4 was be VBD cord-006870-f5w6fw6q 4471 5 higher high JJR cord-006870-f5w6fw6q 4471 6 in in IN cord-006870-f5w6fw6q 4471 7 males male NNS cord-006870-f5w6fw6q 4471 8 ( ( -LRB- cord-006870-f5w6fw6q 4471 9 11.78/100,000 11.78/100,000 CD cord-006870-f5w6fw6q 4471 10 per per IN cord-006870-f5w6fw6q 4471 11 year year NN cord-006870-f5w6fw6q 4471 12 ) ) -RRB- cord-006870-f5w6fw6q 4471 13 than than IN cord-006870-f5w6fw6q 4471 14 females female NNS cord-006870-f5w6fw6q 4471 15 ( ( -LRB- cord-006870-f5w6fw6q 4471 16 8.21/100,000 8.21/100,000 CD cord-006870-f5w6fw6q 4471 17 per per IN cord-006870-f5w6fw6q 4471 18 year year NN cord-006870-f5w6fw6q 4471 19 ) ) -RRB- cord-006870-f5w6fw6q 4471 20 . . . cord-006870-f5w6fw6q 4472 1 The the DT cord-006870-f5w6fw6q 4472 2 highest high JJS cord-006870-f5w6fw6q 4472 3 rates rate NNS cord-006870-f5w6fw6q 4472 4 were be VBD cord-006870-f5w6fw6q 4472 5 in in IN cord-006870-f5w6fw6q 4472 6 the the DT cord-006870-f5w6fw6q 4472 7 age age NN cord-006870-f5w6fw6q 4472 8 group group NN cord-006870-f5w6fw6q 4472 9 70 70 CD cord-006870-f5w6fw6q 4472 10 - - HYPH cord-006870-f5w6fw6q 4472 11 79 79 CD cord-006870-f5w6fw6q 4472 12 years year NNS cord-006870-f5w6fw6q 4472 13 : : : cord-006870-f5w6fw6q 4472 14 20.7 20.7 CD cord-006870-f5w6fw6q 4472 15 and and CC cord-006870-f5w6fw6q 4472 16 32.9 32.9 CD cord-006870-f5w6fw6q 4472 17 per per IN cord-006870-f5w6fw6q 4472 18 100,000 100,000 CD cord-006870-f5w6fw6q 4472 19 per per IN cord-006870-f5w6fw6q 4472 20 year year NN cord-006870-f5w6fw6q 4472 21 for for IN cord-006870-f5w6fw6q 4472 22 females female NNS cord-006870-f5w6fw6q 4472 23 and and CC cord-006870-f5w6fw6q 4472 24 males male NNS cord-006870-f5w6fw6q 4472 25 , , , cord-006870-f5w6fw6q 4472 26 respectively respectively RB cord-006870-f5w6fw6q 4472 27 . . . cord-006870-f5w6fw6q 4473 1 The the DT cord-006870-f5w6fw6q 4473 2 mean mean JJ cord-006870-f5w6fw6q 4473 3 age age NN cord-006870-f5w6fw6q 4473 4 of of IN cord-006870-f5w6fw6q 4473 5 SRSE SRSE NNP cord-006870-f5w6fw6q 4473 6 patients patient NNS cord-006870-f5w6fw6q 4473 7 was be VBD cord-006870-f5w6fw6q 4473 8 52 52 CD cord-006870-f5w6fw6q 4473 9 years year NNS cord-006870-f5w6fw6q 4473 10 ( ( -LRB- cord-006870-f5w6fw6q 4473 11 SD=22 SD=22 NNP cord-006870-f5w6fw6q 4473 12 years year NNS cord-006870-f5w6fw6q 4473 13 ) ) -RRB- cord-006870-f5w6fw6q 4473 14 , , , cord-006870-f5w6fw6q 4473 15 with with IN cord-006870-f5w6fw6q 4473 16 58 58 CD cord-006870-f5w6fw6q 4473 17 % % NN cord-006870-f5w6fw6q 4473 18 males male NNS cord-006870-f5w6fw6q 4473 19 . . . cord-006870-f5w6fw6q 4474 1 The the DT cord-006870-f5w6fw6q 4474 2 most most RBS cord-006870-f5w6fw6q 4474 3 common common JJ cord-006870-f5w6fw6q 4474 4 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 4474 5 for for IN cord-006870-f5w6fw6q 4474 6 SRSE SRSE NNP cord-006870-f5w6fw6q 4474 7 included include VBD cord-006870-f5w6fw6q 4474 8 metabolic metabolic JJ cord-006870-f5w6fw6q 4474 9 disturbances disturbance NNS cord-006870-f5w6fw6q 4474 10 ( ( -LRB- cord-006870-f5w6fw6q 4474 11 39 39 CD cord-006870-f5w6fw6q 4474 12 % % NN cord-006870-f5w6fw6q 4474 13 ) ) -RRB- cord-006870-f5w6fw6q 4474 14 , , , cord-006870-f5w6fw6q 4474 15 sepsis sepsis NN cord-006870-f5w6fw6q 4474 16 ( ( -LRB- cord-006870-f5w6fw6q 4474 17 32 32 CD cord-006870-f5w6fw6q 4474 18 % % NN cord-006870-f5w6fw6q 4474 19 ) ) -RRB- cord-006870-f5w6fw6q 4474 20 , , , cord-006870-f5w6fw6q 4474 21 toxic toxic JJ cord-006870-f5w6fw6q 4474 22 withdrawal withdrawal NN cord-006870-f5w6fw6q 4474 23 state state NN cord-006870-f5w6fw6q 4474 24 ( ( -LRB- cord-006870-f5w6fw6q 4474 25 31 31 CD cord-006870-f5w6fw6q 4474 26 % % NN cord-006870-f5w6fw6q 4474 27 ) ) -RRB- cord-006870-f5w6fw6q 4474 28 , , , cord-006870-f5w6fw6q 4474 29 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 4474 30 disease disease NN cord-006870-f5w6fw6q 4474 31 ( ( -LRB- cord-006870-f5w6fw6q 4474 32 22 22 CD cord-006870-f5w6fw6q 4474 33 % % NN cord-006870-f5w6fw6q 4474 34 ) ) -RRB- cord-006870-f5w6fw6q 4474 35 , , , cord-006870-f5w6fw6q 4474 36 and and CC cord-006870-f5w6fw6q 4474 37 head head NN cord-006870-f5w6fw6q 4474 38 trauma trauma NN cord-006870-f5w6fw6q 4474 39 ( ( -LRB- cord-006870-f5w6fw6q 4474 40 13 13 CD cord-006870-f5w6fw6q 4474 41 % % NN cord-006870-f5w6fw6q 4474 42 ) ) -RRB- cord-006870-f5w6fw6q 4474 43 . . . cord-006870-f5w6fw6q 4475 1 In in IN cord-006870-f5w6fw6q 4475 2 - - HYPH cord-006870-f5w6fw6q 4475 3 hospital hospital NN cord-006870-f5w6fw6q 4475 4 mortality mortality NN cord-006870-f5w6fw6q 4475 5 for for IN cord-006870-f5w6fw6q 4475 6 SRSE SRSE NNP cord-006870-f5w6fw6q 4475 7 was be VBD cord-006870-f5w6fw6q 4475 8 21 21 CD cord-006870-f5w6fw6q 4475 9 % % NN cord-006870-f5w6fw6q 4475 10 . . . cord-006870-f5w6fw6q 4476 1 This this DT cord-006870-f5w6fw6q 4476 2 is be VBZ cord-006870-f5w6fw6q 4476 3 the the DT cord-006870-f5w6fw6q 4476 4 first first JJ cord-006870-f5w6fw6q 4476 5 study study NN cord-006870-f5w6fw6q 4476 6 reporting reporting NN cord-006870-f5w6fw6q 4476 7 estimates estimate NNS cord-006870-f5w6fw6q 4476 8 of of IN cord-006870-f5w6fw6q 4476 9 SRSE SRSE NNP cord-006870-f5w6fw6q 4476 10 incidence incidence NN cord-006870-f5w6fw6q 4476 11 in in IN cord-006870-f5w6fw6q 4476 12 Canada Canada NNP cord-006870-f5w6fw6q 4476 13 . . . cord-006870-f5w6fw6q 4477 1 These these DT cord-006870-f5w6fw6q 4477 2 results result NNS cord-006870-f5w6fw6q 4477 3 suggest suggest VBP cord-006870-f5w6fw6q 4477 4 that that IN cord-006870-f5w6fw6q 4477 5 SRSE SRSE NNP cord-006870-f5w6fw6q 4477 6 is be VBZ cord-006870-f5w6fw6q 4477 7 associated associate VBN cord-006870-f5w6fw6q 4477 8 with with IN cord-006870-f5w6fw6q 4477 9 a a DT cord-006870-f5w6fw6q 4477 10 substantial substantial JJ cord-006870-f5w6fw6q 4477 11 disease disease NN cord-006870-f5w6fw6q 4477 12 burden burden NN cord-006870-f5w6fw6q 4477 13 . . . cord-006870-f5w6fw6q 4478 1 Interventions intervention NNS cord-006870-f5w6fw6q 4478 2 that that WDT cord-006870-f5w6fw6q 4478 3 improve improve VBP cord-006870-f5w6fw6q 4478 4 patient patient JJ cord-006870-f5w6fw6q 4478 5 outcomes outcome NNS cord-006870-f5w6fw6q 4478 6 and and CC cord-006870-f5w6fw6q 4478 7 reduce reduce VB cord-006870-f5w6fw6q 4478 8 mortality mortality NN cord-006870-f5w6fw6q 4478 9 are be VBP cord-006870-f5w6fw6q 4478 10 required require VBN cord-006870-f5w6fw6q 4478 11 . . . cord-006870-f5w6fw6q 4479 1 New new JJ cord-006870-f5w6fw6q 4479 2 - - HYPH cord-006870-f5w6fw6q 4479 3 onset onset NN cord-006870-f5w6fw6q 4479 4 refractory refractory JJ cord-006870-f5w6fw6q 4479 5 status status NN cord-006870-f5w6fw6q 4479 6 epilepticus epilepticus NN cord-006870-f5w6fw6q 4479 7 ( ( -LRB- cord-006870-f5w6fw6q 4479 8 NORSE NORSE NNP cord-006870-f5w6fw6q 4479 9 ) ) -RRB- cord-006870-f5w6fw6q 4479 10 is be VBZ cord-006870-f5w6fw6q 4479 11 a a DT cord-006870-f5w6fw6q 4479 12 condition condition NN cord-006870-f5w6fw6q 4479 13 characterized characterize VBN cord-006870-f5w6fw6q 4479 14 by by IN cord-006870-f5w6fw6q 4479 15 prolonged prolong VBN cord-006870-f5w6fw6q 4479 16 pharmacoresistant pharmacoresistant JJ cord-006870-f5w6fw6q 4479 17 seizures seizure NNS cord-006870-f5w6fw6q 4479 18 in in IN cord-006870-f5w6fw6q 4479 19 a a DT cord-006870-f5w6fw6q 4479 20 previously previously RB cord-006870-f5w6fw6q 4479 21 healthy healthy JJ cord-006870-f5w6fw6q 4479 22 individual individual NN cord-006870-f5w6fw6q 4479 23 with with IN cord-006870-f5w6fw6q 4479 24 no no DT cord-006870-f5w6fw6q 4479 25 identifiable identifiable JJ cord-006870-f5w6fw6q 4479 26 etiology etiology NN cord-006870-f5w6fw6q 4479 27 during during IN cord-006870-f5w6fw6q 4479 28 initial initial JJ cord-006870-f5w6fw6q 4479 29 evaluation evaluation NN cord-006870-f5w6fw6q 4479 30 . . . cord-006870-f5w6fw6q 4480 1 Typical typical JJ cord-006870-f5w6fw6q 4480 2 magnetic magnetic JJ cord-006870-f5w6fw6q 4480 3 resonance resonance NN cord-006870-f5w6fw6q 4480 4 imaging imaging NN cord-006870-f5w6fw6q 4480 5 ( ( -LRB- cord-006870-f5w6fw6q 4480 6 MRI MRI NNP cord-006870-f5w6fw6q 4480 7 ) ) -RRB- cord-006870-f5w6fw6q 4480 8 findings finding NNS cord-006870-f5w6fw6q 4480 9 include include VBP cord-006870-f5w6fw6q 4480 10 bilateral bilateral JJ cord-006870-f5w6fw6q 4480 11 limbic limbic JJ cord-006870-f5w6fw6q 4480 12 and and CC cord-006870-f5w6fw6q 4480 13 neocortical neocortical JJ cord-006870-f5w6fw6q 4480 14 T2-weighted t2-weighte VBD cord-006870-f5w6fw6q 4480 15 hyperintense hyperintense NN cord-006870-f5w6fw6q 4480 16 lesions lesion NNS cord-006870-f5w6fw6q 4480 17 . . . cord-006870-f5w6fw6q 4481 1 Fluorodeoxyglucose Fluorodeoxyglucose NNP cord-006870-f5w6fw6q 4481 2 ( ( -LRB- cord-006870-f5w6fw6q 4481 3 FDG)-positron FDG)-positron NNP cord-006870-f5w6fw6q 4481 4 emission emission NN cord-006870-f5w6fw6q 4481 5 tomography tomography NN cord-006870-f5w6fw6q 4482 1 ( ( -LRB- cord-006870-f5w6fw6q 4482 2 PET PET NNP cord-006870-f5w6fw6q 4482 3 ) ) -RRB- cord-006870-f5w6fw6q 4482 4 findings finding NNS cord-006870-f5w6fw6q 4482 5 have have VBP cord-006870-f5w6fw6q 4482 6 not not RB cord-006870-f5w6fw6q 4482 7 been be VBN cord-006870-f5w6fw6q 4482 8 previously previously RB cord-006870-f5w6fw6q 4482 9 reported report VBN cord-006870-f5w6fw6q 4482 10 . . . cord-006870-f5w6fw6q 4483 1 This this DT cord-006870-f5w6fw6q 4483 2 study study NN cord-006870-f5w6fw6q 4483 3 sought seek VBD cord-006870-f5w6fw6q 4483 4 to to TO cord-006870-f5w6fw6q 4483 5 describe describe VB cord-006870-f5w6fw6q 4483 6 FDG FDG NNP cord-006870-f5w6fw6q 4483 7 - - HYPH cord-006870-f5w6fw6q 4483 8 PET PET NNP cord-006870-f5w6fw6q 4483 9 and and CC cord-006870-f5w6fw6q 4483 10 MRI MRI NNP cord-006870-f5w6fw6q 4483 11 characteristics characteristic NNS cord-006870-f5w6fw6q 4483 12 in in IN cord-006870-f5w6fw6q 4483 13 patients patient NNS cord-006870-f5w6fw6q 4483 14 with with IN cord-006870-f5w6fw6q 4483 15 NORSE NORSE NNP cord-006870-f5w6fw6q 4483 16 . . . cord-006870-f5w6fw6q 4484 1 Methods method NNS cord-006870-f5w6fw6q 4484 2 12 12 CD cord-006870-f5w6fw6q 4484 3 patients patient NNS cord-006870-f5w6fw6q 4484 4 were be VBD cord-006870-f5w6fw6q 4484 5 retrospectively retrospectively RB cord-006870-f5w6fw6q 4484 6 identified identify VBN cord-006870-f5w6fw6q 4484 7 amongst amongst IN cord-006870-f5w6fw6q 4484 8 a a DT cord-006870-f5w6fw6q 4484 9 database database NN cord-006870-f5w6fw6q 4484 10 of of IN cord-006870-f5w6fw6q 4484 11 autoimmune autoimmune NN cord-006870-f5w6fw6q 4484 12 - - HYPH cord-006870-f5w6fw6q 4484 13 mediated mediate VBN cord-006870-f5w6fw6q 4484 14 encephalitis encephalitis RB cord-006870-f5w6fw6q 4484 15 from from IN cord-006870-f5w6fw6q 4484 16 2008 2008 CD cord-006870-f5w6fw6q 4484 17 - - SYM cord-006870-f5w6fw6q 4484 18 2017 2017 CD cord-006870-f5w6fw6q 4484 19 , , , cord-006870-f5w6fw6q 4484 20 meeting meet VBG cord-006870-f5w6fw6q 4484 21 diagnostic diagnostic JJ cord-006870-f5w6fw6q 4484 22 criteria criterion NNS cord-006870-f5w6fw6q 4484 23 for for IN cord-006870-f5w6fw6q 4484 24 NORSE NORSE NNP cord-006870-f5w6fw6q 4484 25 and and CC cord-006870-f5w6fw6q 4484 26 having have VBG cord-006870-f5w6fw6q 4484 27 undergone undergo VBN cord-006870-f5w6fw6q 4484 28 MRI MRI NNP cord-006870-f5w6fw6q 4484 29 and and CC cord-006870-f5w6fw6q 4484 30 PET pet NN cord-006870-f5w6fw6q 4484 31 over over IN cord-006870-f5w6fw6q 4484 32 the the DT cord-006870-f5w6fw6q 4484 33 course course NN cord-006870-f5w6fw6q 4484 34 of of IN cord-006870-f5w6fw6q 4484 35 their -PRON- PRP$ cord-006870-f5w6fw6q 4484 36 illness illness NN cord-006870-f5w6fw6q 4484 37 . . . cord-006870-f5w6fw6q 4485 1 Imaging imaging NN cord-006870-f5w6fw6q 4485 2 findings finding NNS cord-006870-f5w6fw6q 4485 3 were be VBD cord-006870-f5w6fw6q 4485 4 confirmed confirm VBN cord-006870-f5w6fw6q 4485 5 with with IN cord-006870-f5w6fw6q 4485 6 a a DT cord-006870-f5w6fw6q 4485 7 board board NN cord-006870-f5w6fw6q 4485 8 - - HYPH cord-006870-f5w6fw6q 4485 9 certified certify VBN cord-006870-f5w6fw6q 4485 10 neuroradiologist neuroradiologist NN cord-006870-f5w6fw6q 4485 11 . . . cord-006870-f5w6fw6q 4486 1 Nine nine CD cord-006870-f5w6fw6q 4486 2 patients patient NNS cord-006870-f5w6fw6q 4486 3 were be VBD cord-006870-f5w6fw6q 4486 4 autoantibody autoantibody NNP cord-006870-f5w6fw6q 4486 5 positive positive JJ cord-006870-f5w6fw6q 4486 6 : : : cord-006870-f5w6fw6q 4487 1 three three CD cord-006870-f5w6fw6q 4487 2 N n CD cord-006870-f5w6fw6q 4487 3 - - HYPH cord-006870-f5w6fw6q 4487 4 methyl methyl NN cord-006870-f5w6fw6q 4487 5 - - HYPH cord-006870-f5w6fw6q 4487 6 D d NN cord-006870-f5w6fw6q 4487 7 - - HYPH cord-006870-f5w6fw6q 4487 8 aspartic aspartic JJ cord-006870-f5w6fw6q 4487 9 acid acid NN cord-006870-f5w6fw6q 4487 10 ( ( -LRB- cord-006870-f5w6fw6q 4487 11 NMDA NMDA NNP cord-006870-f5w6fw6q 4487 12 ) ) -RRB- cord-006870-f5w6fw6q 4487 13 receptor receptor NN cord-006870-f5w6fw6q 4487 14 , , , cord-006870-f5w6fw6q 4487 15 two two CD cord-006870-f5w6fw6q 4487 16 glutamic glutamic NN cord-006870-f5w6fw6q 4487 17 acid acid NN cord-006870-f5w6fw6q 4487 18 decarboxylase decarboxylase NN cord-006870-f5w6fw6q 4487 19 ( ( -LRB- cord-006870-f5w6fw6q 4487 20 GAD GAD NNP cord-006870-f5w6fw6q 4487 21 ) ) -RRB- cord-006870-f5w6fw6q 4487 22 , , , cord-006870-f5w6fw6q 4487 23 three three CD cord-006870-f5w6fw6q 4487 24 voltage voltage NN cord-006870-f5w6fw6q 4487 25 - - HYPH cord-006870-f5w6fw6q 4487 26 gated gate VBN cord-006870-f5w6fw6q 4487 27 potassium potassium NN cord-006870-f5w6fw6q 4487 28 channel channel NN cord-006870-f5w6fw6q 4487 29 ( ( -LRB- cord-006870-f5w6fw6q 4487 30 VGKC)-complex VGKC)-complex NNP cord-006870-f5w6fw6q 4487 31 with with IN cord-006870-f5w6fw6q 4487 32 two two CD cord-006870-f5w6fw6q 4487 33 having have VBG cord-006870-f5w6fw6q 4487 34 leucine leucine NN cord-006870-f5w6fw6q 4487 35 - - HYPH cord-006870-f5w6fw6q 4487 36 rich rich JJ cord-006870-f5w6fw6q 4487 37 glioma glioma NN cord-006870-f5w6fw6q 4487 38 - - HYPH cord-006870-f5w6fw6q 4487 39 inactivated inactivate VBN cord-006870-f5w6fw6q 4487 40 protein protein NN cord-006870-f5w6fw6q 4487 41 1 1 CD cord-006870-f5w6fw6q 4487 42 IgG IgG NNP cord-006870-f5w6fw6q 4487 43 positivity positivity NN cord-006870-f5w6fw6q 4487 44 , , , cord-006870-f5w6fw6q 4487 45 and and CC cord-006870-f5w6fw6q 4487 46 one one CD cord-006870-f5w6fw6q 4487 47 gamma gamma NN cord-006870-f5w6fw6q 4487 48 - - HYPH cord-006870-f5w6fw6q 4487 49 aminobutyric aminobutyric NN cord-006870-f5w6fw6q 4487 50 acid acid NN cord-006870-f5w6fw6q 4487 51 ( ( -LRB- cord-006870-f5w6fw6q 4487 52 GABA GABA NNP cord-006870-f5w6fw6q 4487 53 ) ) -RRB- cord-006870-f5w6fw6q 4487 54 B b NN cord-006870-f5w6fw6q 4487 55 receptor receptor NN cord-006870-f5w6fw6q 4487 56 . . . cord-006870-f5w6fw6q 4488 1 All all DT cord-006870-f5w6fw6q 4488 2 patients patient NNS cord-006870-f5w6fw6q 4488 3 had have VBD cord-006870-f5w6fw6q 4488 4 identifiable identifiable JJ cord-006870-f5w6fw6q 4488 5 abnormalities abnormality NNS cord-006870-f5w6fw6q 4488 6 on on IN cord-006870-f5w6fw6q 4488 7 FDG FDG NNP cord-006870-f5w6fw6q 4488 8 - - HYPH cord-006870-f5w6fw6q 4488 9 PET PET NNP cord-006870-f5w6fw6q 4488 10 . . . cord-006870-f5w6fw6q 4489 1 Hypometabolism Hypometabolism NNP cord-006870-f5w6fw6q 4489 2 was be VBD cord-006870-f5w6fw6q 4489 3 most most RBS cord-006870-f5w6fw6q 4489 4 common common JJ cord-006870-f5w6fw6q 4489 5 , , , cord-006870-f5w6fw6q 4489 6 with with IN cord-006870-f5w6fw6q 4489 7 11 11 CD cord-006870-f5w6fw6q 4489 8 of of IN cord-006870-f5w6fw6q 4489 9 12 12 CD cord-006870-f5w6fw6q 4489 10 patients patient NNS cord-006870-f5w6fw6q 4489 11 having have VBG cord-006870-f5w6fw6q 4489 12 diffuse diffuse JJ cord-006870-f5w6fw6q 4489 13 , , , cord-006870-f5w6fw6q 4489 14 bilateral bilateral JJ cord-006870-f5w6fw6q 4489 15 , , , cord-006870-f5w6fw6q 4489 16 or or CC cord-006870-f5w6fw6q 4489 17 unilateral unilateral JJ cord-006870-f5w6fw6q 4489 18 frontal frontal JJ cord-006870-f5w6fw6q 4489 19 , , , cord-006870-f5w6fw6q 4489 20 parietal parietal JJ cord-006870-f5w6fw6q 4489 21 , , , cord-006870-f5w6fw6q 4489 22 or or CC cord-006870-f5w6fw6q 4489 23 occipital occipital JJ cord-006870-f5w6fw6q 4489 24 cortical cortical JJ cord-006870-f5w6fw6q 4489 25 hypometabolism hypometabolism NN cord-006870-f5w6fw6q 4489 26 . . . cord-006870-f5w6fw6q 4490 1 Nine nine CD cord-006870-f5w6fw6q 4490 2 patients patient NNS cord-006870-f5w6fw6q 4490 3 also also RB cord-006870-f5w6fw6q 4490 4 had have VBD cord-006870-f5w6fw6q 4490 5 bilateral bilateral JJ cord-006870-f5w6fw6q 4490 6 ( ( -LRB- cord-006870-f5w6fw6q 4490 7 7 7 CD cord-006870-f5w6fw6q 4490 8 ) ) -RRB- cord-006870-f5w6fw6q 4490 9 or or CC cord-006870-f5w6fw6q 4490 10 unilateral unilateral JJ cord-006870-f5w6fw6q 4490 11 ( ( -LRB- cord-006870-f5w6fw6q 4490 12 2 2 CD cord-006870-f5w6fw6q 4490 13 ) ) -RRB- cord-006870-f5w6fw6q 4490 14 mesial mesial JJ cord-006870-f5w6fw6q 4490 15 temporal temporal JJ cord-006870-f5w6fw6q 4490 16 hypermetabolism hypermetabolism NN cord-006870-f5w6fw6q 4490 17 . . . cord-006870-f5w6fw6q 4491 1 Two two CD cord-006870-f5w6fw6q 4491 2 patients patient NNS cord-006870-f5w6fw6q 4491 3 had have VBD cord-006870-f5w6fw6q 4491 4 multifocal multifocal JJ cord-006870-f5w6fw6q 4491 5 hypermetabolism hypermetabolism NN cord-006870-f5w6fw6q 4491 6 with with IN cord-006870-f5w6fw6q 4491 7 bilateral bilateral JJ cord-006870-f5w6fw6q 4491 8 or or CC cord-006870-f5w6fw6q 4491 9 unilateral unilateral JJ cord-006870-f5w6fw6q 4491 10 frontal frontal JJ cord-006870-f5w6fw6q 4491 11 abnormalities abnormality NNS cord-006870-f5w6fw6q 4491 12 in in IN cord-006870-f5w6fw6q 4491 13 addition addition NN cord-006870-f5w6fw6q 4491 14 to to IN cord-006870-f5w6fw6q 4491 15 mesial mesial JJ cord-006870-f5w6fw6q 4491 16 temporal temporal JJ cord-006870-f5w6fw6q 4491 17 findings finding NNS cord-006870-f5w6fw6q 4491 18 . . . cord-006870-f5w6fw6q 4492 1 Of of IN cord-006870-f5w6fw6q 4492 2 the the DT cord-006870-f5w6fw6q 4492 3 nine nine CD cord-006870-f5w6fw6q 4492 4 patients patient NNS cord-006870-f5w6fw6q 4492 5 with with IN cord-006870-f5w6fw6q 4492 6 FDG FDG NNP cord-006870-f5w6fw6q 4492 7 - - HYPH cord-006870-f5w6fw6q 4492 8 PET PET NNP cord-006870-f5w6fw6q 4492 9 hypermetabolism hypermetabolism NN cord-006870-f5w6fw6q 4492 10 , , , cord-006870-f5w6fw6q 4492 11 concurrent concurrent JJ cord-006870-f5w6fw6q 4492 12 MRI MRI NNP cord-006870-f5w6fw6q 4492 13 scans scan NNS cord-006870-f5w6fw6q 4492 14 failed fail VBD cord-006870-f5w6fw6q 4492 15 to to TO cord-006870-f5w6fw6q 4492 16 show show VB cord-006870-f5w6fw6q 4492 17 corresponding correspond VBG cord-006870-f5w6fw6q 4492 18 T2-weighted t2-weighte VBN cord-006870-f5w6fw6q 4492 19 hyperintense hyperintense NN cord-006870-f5w6fw6q 4492 20 lesions lesion NNS cord-006870-f5w6fw6q 4492 21 in in IN cord-006870-f5w6fw6q 4492 22 the the DT cord-006870-f5w6fw6q 4492 23 mesial mesial JJ cord-006870-f5w6fw6q 4492 24 temporal temporal JJ cord-006870-f5w6fw6q 4492 25 and and CC cord-006870-f5w6fw6q 4492 26 medial medial JJ cord-006870-f5w6fw6q 4492 27 frontal frontal JJ cord-006870-f5w6fw6q 4492 28 regions region NNS cord-006870-f5w6fw6q 4492 29 in in IN cord-006870-f5w6fw6q 4492 30 two two CD cord-006870-f5w6fw6q 4492 31 patients patient NNS cord-006870-f5w6fw6q 4492 32 . . . cord-006870-f5w6fw6q 4493 1 FDG FDG NNP cord-006870-f5w6fw6q 4493 2 - - HYPH cord-006870-f5w6fw6q 4493 3 PET PET NNP cord-006870-f5w6fw6q 4493 4 findings finding NNS cord-006870-f5w6fw6q 4493 5 in in IN cord-006870-f5w6fw6q 4493 6 NORSE NORSE NNP cord-006870-f5w6fw6q 4493 7 include include VBP cord-006870-f5w6fw6q 4493 8 bilateral bilateral JJ cord-006870-f5w6fw6q 4493 9 or or CC cord-006870-f5w6fw6q 4493 10 unilateral unilateral JJ cord-006870-f5w6fw6q 4493 11 mesial mesial JJ cord-006870-f5w6fw6q 4493 12 temporal temporal JJ cord-006870-f5w6fw6q 4493 13 or or CC cord-006870-f5w6fw6q 4493 14 mesial mesial JJ cord-006870-f5w6fw6q 4493 15 frontal frontal JJ cord-006870-f5w6fw6q 4493 16 hypermetabolism hypermetabolism NN cord-006870-f5w6fw6q 4493 17 with with IN cord-006870-f5w6fw6q 4493 18 diffuse diffuse NN cord-006870-f5w6fw6q 4493 19 , , , cord-006870-f5w6fw6q 4493 20 bilateral bilateral JJ cord-006870-f5w6fw6q 4493 21 , , , cord-006870-f5w6fw6q 4493 22 or or CC cord-006870-f5w6fw6q 4493 23 focal focal JJ cord-006870-f5w6fw6q 4493 24 cortical cortical JJ cord-006870-f5w6fw6q 4493 25 hypometabolism hypometabolism NN cord-006870-f5w6fw6q 4493 26 . . . cord-006870-f5w6fw6q 4494 1 Hypermetabolism Hypermetabolism NNP cord-006870-f5w6fw6q 4494 2 may may MD cord-006870-f5w6fw6q 4494 3 reflect reflect VB cord-006870-f5w6fw6q 4494 4 regions region NNS cord-006870-f5w6fw6q 4494 5 predominantly predominantly RB cord-006870-f5w6fw6q 4494 6 involved involve VBN cord-006870-f5w6fw6q 4494 7 in in IN cord-006870-f5w6fw6q 4494 8 acute acute JJ cord-006870-f5w6fw6q 4494 9 epileptogenesis epileptogenesis NN cord-006870-f5w6fw6q 4494 10 . . . cord-006870-f5w6fw6q 4495 1 FDG FDG NNP cord-006870-f5w6fw6q 4495 2 - - HYPH cord-006870-f5w6fw6q 4495 3 PET PET NNP cord-006870-f5w6fw6q 4495 4 may may MD cord-006870-f5w6fw6q 4495 5 improve improve VB cord-006870-f5w6fw6q 4495 6 sensitivity sensitivity NN cord-006870-f5w6fw6q 4495 7 when when WRB cord-006870-f5w6fw6q 4495 8 compared compare VBN cord-006870-f5w6fw6q 4495 9 to to IN cord-006870-f5w6fw6q 4495 10 MRI MRI NNP cord-006870-f5w6fw6q 4495 11 alone alone RB cord-006870-f5w6fw6q 4495 12 . . . cord-006870-f5w6fw6q 4496 1 While while IN cord-006870-f5w6fw6q 4496 2 seizures seizure NNS cord-006870-f5w6fw6q 4496 3 are be VBP cord-006870-f5w6fw6q 4496 4 uncommon uncommon JJ cord-006870-f5w6fw6q 4496 5 but but CC cord-006870-f5w6fw6q 4496 6 reported report VBN cord-006870-f5w6fw6q 4496 7 in in IN cord-006870-f5w6fw6q 4496 8 primary primary JJ cord-006870-f5w6fw6q 4496 9 intraventricular intraventricular JJ cord-006870-f5w6fw6q 4496 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4496 11 ( ( -LRB- cord-006870-f5w6fw6q 4496 12 IVH IVH NNP cord-006870-f5w6fw6q 4496 13 ) ) -RRB- cord-006870-f5w6fw6q 4496 14 , , , cord-006870-f5w6fw6q 4496 15 little little JJ cord-006870-f5w6fw6q 4496 16 evidence evidence NN cord-006870-f5w6fw6q 4496 17 is be VBZ cord-006870-f5w6fw6q 4496 18 available available JJ cord-006870-f5w6fw6q 4496 19 on on IN cord-006870-f5w6fw6q 4496 20 the the DT cord-006870-f5w6fw6q 4496 21 prevalence prevalence NN cord-006870-f5w6fw6q 4496 22 of of IN cord-006870-f5w6fw6q 4496 23 hyperexcitable hyperexcitable JJ cord-006870-f5w6fw6q 4496 24 patterns pattern NNS cord-006870-f5w6fw6q 4496 25 on on IN cord-006870-f5w6fw6q 4496 26 long long JJ cord-006870-f5w6fw6q 4496 27 term term NN cord-006870-f5w6fw6q 4496 28 EEG EEG NNP cord-006870-f5w6fw6q 4496 29 monitoring monitoring NN cord-006870-f5w6fw6q 4496 30 . . . cord-006870-f5w6fw6q 4497 1 We -PRON- PRP cord-006870-f5w6fw6q 4497 2 sought seek VBD cord-006870-f5w6fw6q 4497 3 to to TO cord-006870-f5w6fw6q 4497 4 determine determine VB cord-006870-f5w6fw6q 4497 5 the the DT cord-006870-f5w6fw6q 4497 6 prevalence prevalence NN cord-006870-f5w6fw6q 4497 7 of of IN cord-006870-f5w6fw6q 4497 8 hyperexcitable hyperexcitable JJ cord-006870-f5w6fw6q 4497 9 patterns pattern NNS cord-006870-f5w6fw6q 4497 10 and and CC cord-006870-f5w6fw6q 4497 11 seizures seizure NNS cord-006870-f5w6fw6q 4497 12 in in IN cord-006870-f5w6fw6q 4497 13 patients patient NNS cord-006870-f5w6fw6q 4497 14 with with IN cord-006870-f5w6fw6q 4497 15 primary primary JJ cord-006870-f5w6fw6q 4497 16 IVH IVH NNP cord-006870-f5w6fw6q 4497 17 who who WP cord-006870-f5w6fw6q 4497 18 were be VBD cord-006870-f5w6fw6q 4497 19 extracted extract VBN cord-006870-f5w6fw6q 4497 20 from from IN cord-006870-f5w6fw6q 4497 21 a a DT cord-006870-f5w6fw6q 4497 22 cohort cohort NN cord-006870-f5w6fw6q 4497 23 consisting consist VBG cord-006870-f5w6fw6q 4497 24 of of IN cord-006870-f5w6fw6q 4497 25 patients patient NNS cord-006870-f5w6fw6q 4497 26 with with IN cord-006870-f5w6fw6q 4497 27 spontaneous spontaneous JJ cord-006870-f5w6fw6q 4497 28 intracerebral intracerebral JJ cord-006870-f5w6fw6q 4497 29 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4497 30 ( ( -LRB- cord-006870-f5w6fw6q 4497 31 sICH sich NN cord-006870-f5w6fw6q 4497 32 ) ) -RRB- cord-006870-f5w6fw6q 4497 33 who who WP cord-006870-f5w6fw6q 4497 34 underwent undergo VBD cord-006870-f5w6fw6q 4497 35 continuous continuous JJ cord-006870-f5w6fw6q 4497 36 electroencephalogram electroencephalogram FW cord-006870-f5w6fw6q 4497 37 ( ( -LRB- cord-006870-f5w6fw6q 4497 38 cEEG ceeg FW cord-006870-f5w6fw6q 4497 39 ) ) -RRB- cord-006870-f5w6fw6q 4497 40 monitoring monitoring NN cord-006870-f5w6fw6q 4497 41 between between IN cord-006870-f5w6fw6q 4497 42 January January NNP cord-006870-f5w6fw6q 4497 43 2013 2013 CD cord-006870-f5w6fw6q 4497 44 and and CC cord-006870-f5w6fw6q 4497 45 December December NNP cord-006870-f5w6fw6q 4497 46 2016 2016 CD cord-006870-f5w6fw6q 4497 47 at at IN cord-006870-f5w6fw6q 4497 48 Yale Yale NNP cord-006870-f5w6fw6q 4497 49 - - HYPH cord-006870-f5w6fw6q 4497 50 New New NNP cord-006870-f5w6fw6q 4497 51 Haven Haven NNP cord-006870-f5w6fw6q 4497 52 Hospital Hospital NNP cord-006870-f5w6fw6q 4497 53 . . . cord-006870-f5w6fw6q 4498 1 Indications indication NNS cord-006870-f5w6fw6q 4498 2 for for IN cord-006870-f5w6fw6q 4498 3 cEEG ceeg JJ cord-006870-f5w6fw6q 4498 4 monitoring monitoring NN cord-006870-f5w6fw6q 4498 5 included include VBD cord-006870-f5w6fw6q 4498 6 fluctuation fluctuation NN cord-006870-f5w6fw6q 4498 7 of of IN cord-006870-f5w6fw6q 4498 8 or or CC cord-006870-f5w6fw6q 4498 9 depressed depressed JJ cord-006870-f5w6fw6q 4498 10 mental mental JJ cord-006870-f5w6fw6q 4498 11 status status NN cord-006870-f5w6fw6q 4498 12 , , , cord-006870-f5w6fw6q 4498 13 abnormal abnormal JJ cord-006870-f5w6fw6q 4498 14 movements movement NNS cord-006870-f5w6fw6q 4498 15 and and CC cord-006870-f5w6fw6q 4498 16 a a DT cord-006870-f5w6fw6q 4498 17 limited limited JJ cord-006870-f5w6fw6q 4498 18 clinical clinical JJ cord-006870-f5w6fw6q 4498 19 exam exam NN cord-006870-f5w6fw6q 4498 20 . . . cord-006870-f5w6fw6q 4499 1 We -PRON- PRP cord-006870-f5w6fw6q 4499 2 recorded record VBD cord-006870-f5w6fw6q 4499 3 demographics demographic NNS cord-006870-f5w6fw6q 4499 4 , , , cord-006870-f5w6fw6q 4499 5 radiologic radiologic JJ cord-006870-f5w6fw6q 4499 6 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 4499 7 , , , cord-006870-f5w6fw6q 4499 8 duration duration NN cord-006870-f5w6fw6q 4499 9 of of IN cord-006870-f5w6fw6q 4499 10 EEG EEG NNP cord-006870-f5w6fw6q 4499 11 recording recording NN cord-006870-f5w6fw6q 4499 12 and and CC cord-006870-f5w6fw6q 4499 13 EEG EEG NNP cord-006870-f5w6fw6q 4499 14 findings finding NNS cord-006870-f5w6fw6q 4499 15 . . . cord-006870-f5w6fw6q 4500 1 Hyperexcitable hyperexcitable JJ cord-006870-f5w6fw6q 4500 2 patterns pattern NNS cord-006870-f5w6fw6q 4500 3 comprised comprise VBN cord-006870-f5w6fw6q 4500 4 generalized generalized JJ cord-006870-f5w6fw6q 4500 5 , , , cord-006870-f5w6fw6q 4500 6 bilateral bilateral JJ cord-006870-f5w6fw6q 4500 7 independent independent JJ cord-006870-f5w6fw6q 4500 8 or or CC cord-006870-f5w6fw6q 4500 9 lateralized lateralized JJ cord-006870-f5w6fw6q 4500 10 periodic periodic JJ cord-006870-f5w6fw6q 4500 11 discharges discharge NNS cord-006870-f5w6fw6q 4500 12 ( ( -LRB- cord-006870-f5w6fw6q 4500 13 PDs pd NNS cord-006870-f5w6fw6q 4500 14 ) ) -RRB- cord-006870-f5w6fw6q 4500 15 , , , cord-006870-f5w6fw6q 4500 16 lateralized lateralized JJ cord-006870-f5w6fw6q 4500 17 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4500 18 delta delta NN cord-006870-f5w6fw6q 4500 19 activity activity NN cord-006870-f5w6fw6q 4500 20 ( ( -LRB- cord-006870-f5w6fw6q 4500 21 RDA RDA NNP cord-006870-f5w6fw6q 4500 22 ) ) -RRB- cord-006870-f5w6fw6q 4500 23 , , , cord-006870-f5w6fw6q 4500 24 brief brief VBP cord-006870-f5w6fw6q 4500 25 potentially potentially RB cord-006870-f5w6fw6q 4500 26 ictal ictal JJ cord-006870-f5w6fw6q 4500 27 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4500 28 discharges discharge NNS cord-006870-f5w6fw6q 4500 29 ( ( -LRB- cord-006870-f5w6fw6q 4500 30 B(I)RDs B(I)RDs NNP cord-006870-f5w6fw6q 4500 31 ) ) -RRB- cord-006870-f5w6fw6q 4500 32 , , , cord-006870-f5w6fw6q 4500 33 and and CC cord-006870-f5w6fw6q 4500 34 spike spike NN cord-006870-f5w6fw6q 4500 35 - - HYPH cord-006870-f5w6fw6q 4500 36 and and CC cord-006870-f5w6fw6q 4500 37 - - HYPH cord-006870-f5w6fw6q 4500 38 wave wave NN cord-006870-f5w6fw6q 4500 39 discharges discharge NNS cord-006870-f5w6fw6q 4500 40 ( ( -LRB- cord-006870-f5w6fw6q 4500 41 SW SW NNP cord-006870-f5w6fw6q 4500 42 ) ) -RRB- cord-006870-f5w6fw6q 4500 43 . . . cord-006870-f5w6fw6q 4501 1 Of of IN cord-006870-f5w6fw6q 4501 2 196 196 CD cord-006870-f5w6fw6q 4501 3 adults adult NNS cord-006870-f5w6fw6q 4501 4 with with IN cord-006870-f5w6fw6q 4501 5 sICH sich NN cord-006870-f5w6fw6q 4501 6 who who WP cord-006870-f5w6fw6q 4501 7 had have VBD cord-006870-f5w6fw6q 4501 8 cEEG cEEG VBN cord-006870-f5w6fw6q 4501 9 performed perform VBN cord-006870-f5w6fw6q 4501 10 , , , cord-006870-f5w6fw6q 4501 11 13 13 CD cord-006870-f5w6fw6q 4501 12 patients patient NNS cord-006870-f5w6fw6q 4501 13 had have VBD cord-006870-f5w6fw6q 4501 14 primary primary JJ cord-006870-f5w6fw6q 4501 15 IVH IVH NNP cord-006870-f5w6fw6q 4501 16 . . . cord-006870-f5w6fw6q 4502 1 Hydrocephalus Hydrocephalus NNP cord-006870-f5w6fw6q 4502 2 was be VBD cord-006870-f5w6fw6q 4502 3 present present JJ cord-006870-f5w6fw6q 4502 4 in in IN cord-006870-f5w6fw6q 4502 5 9 9 CD cord-006870-f5w6fw6q 4502 6 patients patient NNS cord-006870-f5w6fw6q 4502 7 ( ( -LRB- cord-006870-f5w6fw6q 4502 8 69 69 CD cord-006870-f5w6fw6q 4502 9 % % NN cord-006870-f5w6fw6q 4502 10 ) ) -RRB- cord-006870-f5w6fw6q 4502 11 . . . cord-006870-f5w6fw6q 4503 1 Patients patient NNS cord-006870-f5w6fw6q 4503 2 were be VBD cord-006870-f5w6fw6q 4503 3 monitored monitor VBN cord-006870-f5w6fw6q 4503 4 for for IN cord-006870-f5w6fw6q 4503 5 a a DT cord-006870-f5w6fw6q 4503 6 mean mean JJ cord-006870-f5w6fw6q 4503 7 duration duration NN cord-006870-f5w6fw6q 4503 8 of of IN cord-006870-f5w6fw6q 4503 9 22.4 22.4 CD cord-006870-f5w6fw6q 4503 10 ( ( -LRB- cord-006870-f5w6fw6q 4503 11 ± ± CD cord-006870-f5w6fw6q 4503 12 14.7 14.7 CD cord-006870-f5w6fw6q 4503 13 ) ) -RRB- cord-006870-f5w6fw6q 4503 14 hours hour NNS cord-006870-f5w6fw6q 4503 15 . . . cord-006870-f5w6fw6q 4504 1 9 9 CD cord-006870-f5w6fw6q 4504 2 patients patient NNS cord-006870-f5w6fw6q 4504 3 had have VBD cord-006870-f5w6fw6q 4504 4 hyperexcitable hyperexcitable JJ cord-006870-f5w6fw6q 4504 5 patterns pattern NNS cord-006870-f5w6fw6q 4504 6 and/or and/or CC cord-006870-f5w6fw6q 4504 7 electrographic electrographic JJ cord-006870-f5w6fw6q 4504 8 seizures seizure NNS cord-006870-f5w6fw6q 4504 9 ( ( -LRB- cord-006870-f5w6fw6q 4504 10 70 70 CD cord-006870-f5w6fw6q 4504 11 % % NN cord-006870-f5w6fw6q 4504 12 ) ) -RRB- cord-006870-f5w6fw6q 4504 13 : : : cord-006870-f5w6fw6q 4505 1 Electrographic electrographic JJ cord-006870-f5w6fw6q 4505 2 seizures seizure NNS cord-006870-f5w6fw6q 4505 3 and and CC cord-006870-f5w6fw6q 4505 4 co co JJ cord-006870-f5w6fw6q 4505 5 - - JJ cord-006870-f5w6fw6q 4505 6 existent existent JJ cord-006870-f5w6fw6q 4505 7 hyperexcitable hyperexcitable JJ cord-006870-f5w6fw6q 4505 8 patterns pattern NNS cord-006870-f5w6fw6q 4505 9 were be VBD cord-006870-f5w6fw6q 4505 10 captured capture VBN cord-006870-f5w6fw6q 4505 11 in in IN cord-006870-f5w6fw6q 4505 12 2 2 CD cord-006870-f5w6fw6q 4505 13 of of IN cord-006870-f5w6fw6q 4505 14 13 13 CD cord-006870-f5w6fw6q 4505 15 patients patient NNS cord-006870-f5w6fw6q 4505 16 ( ( -LRB- cord-006870-f5w6fw6q 4505 17 16 16 CD cord-006870-f5w6fw6q 4505 18 % % NN cord-006870-f5w6fw6q 4505 19 ) ) -RRB- cord-006870-f5w6fw6q 4505 20 and and CC cord-006870-f5w6fw6q 4505 21 hyperexcitable hyperexcitable JJ cord-006870-f5w6fw6q 4505 22 patterns pattern NNS cord-006870-f5w6fw6q 4505 23 without without IN cord-006870-f5w6fw6q 4505 24 seizures seizure NNS cord-006870-f5w6fw6q 4505 25 in in IN cord-006870-f5w6fw6q 4505 26 7 7 CD cord-006870-f5w6fw6q 4505 27 of of IN cord-006870-f5w6fw6q 4505 28 13 13 CD cord-006870-f5w6fw6q 4505 29 patients patient NNS cord-006870-f5w6fw6q 4505 30 ( ( -LRB- cord-006870-f5w6fw6q 4505 31 54 54 CD cord-006870-f5w6fw6q 4505 32 % % NN cord-006870-f5w6fw6q 4505 33 ) ) -RRB- cord-006870-f5w6fw6q 4505 34 . . . cord-006870-f5w6fw6q 4506 1 Hyperexcitable hyperexcitable JJ cord-006870-f5w6fw6q 4506 2 patterns pattern NNS cord-006870-f5w6fw6q 4506 3 included include VBD cord-006870-f5w6fw6q 4506 4 periodic periodic JJ cord-006870-f5w6fw6q 4506 5 discharges discharge NNS cord-006870-f5w6fw6q 4506 6 ( ( -LRB- cord-006870-f5w6fw6q 4506 7 PDs pd NNS cord-006870-f5w6fw6q 4506 8 ) ) -RRB- cord-006870-f5w6fw6q 4506 9 ( ( -LRB- cord-006870-f5w6fw6q 4506 10 4 4 LS cord-006870-f5w6fw6q 4506 11 ) ) -RRB- cord-006870-f5w6fw6q 4506 12 ( ( -LRB- cord-006870-f5w6fw6q 4506 13 generalized generalize VBN cord-006870-f5w6fw6q 4506 14 , , , cord-006870-f5w6fw6q 4506 15 lateralized lateralized JJ cord-006870-f5w6fw6q 4506 16 and and CC cord-006870-f5w6fw6q 4506 17 bilateral bilateral JJ cord-006870-f5w6fw6q 4506 18 independent independent NN cord-006870-f5w6fw6q 4506 19 , , , cord-006870-f5w6fw6q 4506 20 with with IN cord-006870-f5w6fw6q 4506 21 and and CC cord-006870-f5w6fw6q 4506 22 without without IN cord-006870-f5w6fw6q 4506 23 rhythmicity rhythmicity NNP cord-006870-f5w6fw6q 4506 24 ) ) -RRB- cord-006870-f5w6fw6q 4506 25 , , , cord-006870-f5w6fw6q 4506 26 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4506 27 delta delta NN cord-006870-f5w6fw6q 4506 28 activity activity NN cord-006870-f5w6fw6q 4506 29 ( ( -LRB- cord-006870-f5w6fw6q 4506 30 RDA RDA NNP cord-006870-f5w6fw6q 4506 31 ) ) -RRB- cord-006870-f5w6fw6q 4506 32 ( ( -LRB- cord-006870-f5w6fw6q 4506 33 5 5 LS cord-006870-f5w6fw6q 4506 34 ) ) -RRB- cord-006870-f5w6fw6q 4506 35 ( ( -LRB- cord-006870-f5w6fw6q 4506 36 both both DT cord-006870-f5w6fw6q 4506 37 lateralized lateralized JJ cord-006870-f5w6fw6q 4506 38 and and CC cord-006870-f5w6fw6q 4506 39 generalized generalized JJ cord-006870-f5w6fw6q 4506 40 , , , cord-006870-f5w6fw6q 4506 41 with with IN cord-006870-f5w6fw6q 4506 42 and and CC cord-006870-f5w6fw6q 4506 43 without without IN cord-006870-f5w6fw6q 4506 44 sharps sharps NNP cord-006870-f5w6fw6q 4506 45 ) ) -RRB- cord-006870-f5w6fw6q 4506 46 , , , cord-006870-f5w6fw6q 4506 47 brief brief VBP cord-006870-f5w6fw6q 4506 48 potentially potentially RB cord-006870-f5w6fw6q 4506 49 ictal ictal JJ cord-006870-f5w6fw6q 4506 50 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4506 51 discharges(B(I)RDs discharges(b(i)rd NNS cord-006870-f5w6fw6q 4506 52 ) ) -RRB- cord-006870-f5w6fw6q 4506 53 ( ( -LRB- cord-006870-f5w6fw6q 4506 54 1 1 CD cord-006870-f5w6fw6q 4506 55 ) ) -RRB- cord-006870-f5w6fw6q 4506 56 and and CC cord-006870-f5w6fw6q 4506 57 spike spike NN cord-006870-f5w6fw6q 4506 58 - - HYPH cord-006870-f5w6fw6q 4506 59 and and CC cord-006870-f5w6fw6q 4506 60 - - HYPH cord-006870-f5w6fw6q 4506 61 wave wave NN cord-006870-f5w6fw6q 4506 62 discharges discharge NNS cord-006870-f5w6fw6q 4506 63 ( ( -LRB- cord-006870-f5w6fw6q 4506 64 SW SW NNP cord-006870-f5w6fw6q 4506 65 ) ) -RRB- cord-006870-f5w6fw6q 4506 66 ( ( -LRB- cord-006870-f5w6fw6q 4506 67 1 1 CD cord-006870-f5w6fw6q 4506 68 ) ) -RRB- cord-006870-f5w6fw6q 4506 69 . . . cord-006870-f5w6fw6q 4507 1 There there EX cord-006870-f5w6fw6q 4507 2 was be VBD cord-006870-f5w6fw6q 4507 3 no no DT cord-006870-f5w6fw6q 4507 4 significant significant JJ cord-006870-f5w6fw6q 4507 5 difference difference NN cord-006870-f5w6fw6q 4507 6 between between IN cord-006870-f5w6fw6q 4507 7 patients patient NNS cord-006870-f5w6fw6q 4507 8 with with IN cord-006870-f5w6fw6q 4507 9 and and CC cord-006870-f5w6fw6q 4507 10 without without IN cord-006870-f5w6fw6q 4507 11 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 4507 12 and and CC cord-006870-f5w6fw6q 4507 13 hyperexcitability hyperexcitability NN cord-006870-f5w6fw6q 4507 14 or or CC cord-006870-f5w6fw6q 4507 15 electrographic electrographic JJ cord-006870-f5w6fw6q 4507 16 seizures seizure NNS cord-006870-f5w6fw6q 4507 17 ( ( -LRB- cord-006870-f5w6fw6q 4507 18 p= p= JJ cord-006870-f5w6fw6q 4507 19 0.76 0.76 CD cord-006870-f5w6fw6q 4507 20 ) ) -RRB- cord-006870-f5w6fw6q 4507 21 . . . cord-006870-f5w6fw6q 4508 1 Both both DT cord-006870-f5w6fw6q 4508 2 electrographic electrographic JJ cord-006870-f5w6fw6q 4508 3 seizures seizure NNS cord-006870-f5w6fw6q 4508 4 and/or and/or CC cord-006870-f5w6fw6q 4508 5 patterns pattern NNS cord-006870-f5w6fw6q 4508 6 of of IN cord-006870-f5w6fw6q 4508 7 hyperexcitability hyperexcitability NN cord-006870-f5w6fw6q 4508 8 on on IN cord-006870-f5w6fw6q 4508 9 EEG EEG NNP cord-006870-f5w6fw6q 4508 10 are be VBP cord-006870-f5w6fw6q 4508 11 common common JJ cord-006870-f5w6fw6q 4508 12 in in IN cord-006870-f5w6fw6q 4508 13 our -PRON- PRP$ cord-006870-f5w6fw6q 4508 14 selected selected JJ cord-006870-f5w6fw6q 4508 15 cohort cohort NN cord-006870-f5w6fw6q 4508 16 of of IN cord-006870-f5w6fw6q 4508 17 primary primary JJ cord-006870-f5w6fw6q 4508 18 IVH IVH NNP cord-006870-f5w6fw6q 4508 19 patients patient NNS cord-006870-f5w6fw6q 4508 20 . . . cord-006870-f5w6fw6q 4509 1 This this DT cord-006870-f5w6fw6q 4509 2 underscores underscore VBZ cord-006870-f5w6fw6q 4509 3 the the DT cord-006870-f5w6fw6q 4509 4 importance importance NN cord-006870-f5w6fw6q 4509 5 of of IN cord-006870-f5w6fw6q 4509 6 continuous continuous JJ cord-006870-f5w6fw6q 4509 7 EEG EEG NNP cord-006870-f5w6fw6q 4509 8 monitoring monitoring NN cord-006870-f5w6fw6q 4509 9 in in IN cord-006870-f5w6fw6q 4509 10 this this DT cord-006870-f5w6fw6q 4509 11 patient patient JJ cord-006870-f5w6fw6q 4509 12 population population NN cord-006870-f5w6fw6q 4509 13 , , , cord-006870-f5w6fw6q 4509 14 since since IN cord-006870-f5w6fw6q 4509 15 the the DT cord-006870-f5w6fw6q 4509 16 detection detection NN cord-006870-f5w6fw6q 4509 17 of of IN cord-006870-f5w6fw6q 4509 18 non non JJ cord-006870-f5w6fw6q 4509 19 - - JJ cord-006870-f5w6fw6q 4509 20 convulsive convulsive JJ cord-006870-f5w6fw6q 4509 21 seizures seizure NNS cord-006870-f5w6fw6q 4509 22 may may MD cord-006870-f5w6fw6q 4509 23 offer offer VB cord-006870-f5w6fw6q 4509 24 an an DT cord-006870-f5w6fw6q 4509 25 opportunity opportunity NN cord-006870-f5w6fw6q 4509 26 for for IN cord-006870-f5w6fw6q 4509 27 therapeutic therapeutic JJ cord-006870-f5w6fw6q 4509 28 intervention intervention NN cord-006870-f5w6fw6q 4509 29 . . . cord-006870-f5w6fw6q 4510 1 Patients patient NNS cord-006870-f5w6fw6q 4510 2 with with IN cord-006870-f5w6fw6q 4510 3 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4510 4 SAH SAH NNP cord-006870-f5w6fw6q 4510 5 ( ( -LRB- cord-006870-f5w6fw6q 4510 6 aSAH asah JJ cord-006870-f5w6fw6q 4510 7 ) ) -RRB- cord-006870-f5w6fw6q 4510 8 frequently frequently RB cord-006870-f5w6fw6q 4510 9 have have VBP cord-006870-f5w6fw6q 4510 10 ictal ictal JJ cord-006870-f5w6fw6q 4510 11 - - HYPH cord-006870-f5w6fw6q 4510 12 interictal interictal JJ cord-006870-f5w6fw6q 4510 13 continuum continuum NN cord-006870-f5w6fw6q 4510 14 ( ( -LRB- cord-006870-f5w6fw6q 4510 15 IIC IIC NNP cord-006870-f5w6fw6q 4510 16 ) ) -RRB- cord-006870-f5w6fw6q 4510 17 EEG EEG NNP cord-006870-f5w6fw6q 4510 18 patterns pattern NNS cord-006870-f5w6fw6q 4510 19 . . . cord-006870-f5w6fw6q 4511 1 While while IN cord-006870-f5w6fw6q 4511 2 seizure seizure NN cord-006870-f5w6fw6q 4511 3 burden burden NN cord-006870-f5w6fw6q 4511 4 can can MD cord-006870-f5w6fw6q 4511 5 worsen worsen VB cord-006870-f5w6fw6q 4511 6 outcomes outcome NNS cord-006870-f5w6fw6q 4511 7 , , , cord-006870-f5w6fw6q 4511 8 less less JJR cord-006870-f5w6fw6q 4511 9 is be VBZ cord-006870-f5w6fw6q 4511 10 known know VBN cord-006870-f5w6fw6q 4511 11 about about IN cord-006870-f5w6fw6q 4511 12 IIC IIC NNP cord-006870-f5w6fw6q 4511 13 burden burden NN cord-006870-f5w6fw6q 4511 14 . . . cord-006870-f5w6fw6q 4512 1 We -PRON- PRP cord-006870-f5w6fw6q 4512 2 investigated investigate VBD cord-006870-f5w6fw6q 4512 3 the the DT cord-006870-f5w6fw6q 4512 4 impact impact NN cord-006870-f5w6fw6q 4512 5 of of IN cord-006870-f5w6fw6q 4512 6 IIC IIC NNP cord-006870-f5w6fw6q 4512 7 burden burden NN cord-006870-f5w6fw6q 4512 8 and and CC cord-006870-f5w6fw6q 4512 9 anti anti JJ cord-006870-f5w6fw6q 4512 10 - - JJ cord-006870-f5w6fw6q 4512 11 epileptic epileptic JJ cord-006870-f5w6fw6q 4512 12 drug drug NN cord-006870-f5w6fw6q 4512 13 ( ( -LRB- cord-006870-f5w6fw6q 4512 14 AED AED NNP cord-006870-f5w6fw6q 4512 15 ) ) -RRB- cord-006870-f5w6fw6q 4512 16 treatment treatment NN cord-006870-f5w6fw6q 4512 17 on on IN cord-006870-f5w6fw6q 4512 18 aSAH asah JJ cord-006870-f5w6fw6q 4512 19 outcomes outcome NNS cord-006870-f5w6fw6q 4512 20 . . . cord-006870-f5w6fw6q 4513 1 We -PRON- PRP cord-006870-f5w6fw6q 4513 2 included include VBD cord-006870-f5w6fw6q 4513 3 patients patient NNS cord-006870-f5w6fw6q 4513 4 with with IN cord-006870-f5w6fw6q 4513 5 aSAH asah JJ cord-006870-f5w6fw6q 4513 6 undergoing undergo VBG cord-006870-f5w6fw6q 4513 7 continuous continuous JJ cord-006870-f5w6fw6q 4513 8 EEG EEG NNP cord-006870-f5w6fw6q 4513 9 ( ( -LRB- cord-006870-f5w6fw6q 4513 10 cEEG ceeg JJ cord-006870-f5w6fw6q 4513 11 ) ) -RRB- cord-006870-f5w6fw6q 4513 12 from from IN cord-006870-f5w6fw6q 4513 13 2011 2011 CD cord-006870-f5w6fw6q 4513 14 - - SYM cord-006870-f5w6fw6q 4513 15 2016 2016 CD cord-006870-f5w6fw6q 4513 16 . . . cord-006870-f5w6fw6q 4514 1 Patients patient NNS cord-006870-f5w6fw6q 4514 2 with with IN cord-006870-f5w6fw6q 4514 3 nonaneurysmal nonaneurysmal NNP cord-006870-f5w6fw6q 4514 4 SAH SAH NNP cord-006870-f5w6fw6q 4514 5 or or CC cord-006870-f5w6fw6q 4514 6 90 90 CD cord-006870-f5w6fw6q 4514 7 % % NN cord-006870-f5w6fw6q 4514 8 , , , cord-006870-f5w6fw6q 4514 9 50 50 CD cord-006870-f5w6fw6q 4514 10 - - SYM cord-006870-f5w6fw6q 4514 11 89 89 CD cord-006870-f5w6fw6q 4514 12 % % NN cord-006870-f5w6fw6q 4514 13 , , , cord-006870-f5w6fw6q 4514 14 10 10 CD cord-006870-f5w6fw6q 4514 15 - - SYM cord-006870-f5w6fw6q 4514 16 49 49 CD cord-006870-f5w6fw6q 4514 17 % % NN cord-006870-f5w6fw6q 4514 18 , , , cord-006870-f5w6fw6q 4514 19 1 1 CD cord-006870-f5w6fw6q 4514 20 - - SYM cord-006870-f5w6fw6q 4514 21 9 9 CD cord-006870-f5w6fw6q 4514 22 % % NN cord-006870-f5w6fw6q 4514 23 , , , cord-006870-f5w6fw6q 4514 24 < < XX cord-006870-f5w6fw6q 4514 25 1 1 CD cord-006870-f5w6fw6q 4514 26 % % NN cord-006870-f5w6fw6q 4514 27 . . . cord-006870-f5w6fw6q 4515 1 Age age NN cord-006870-f5w6fw6q 4515 2 gender gender NN cord-006870-f5w6fw6q 4515 3 , , , cord-006870-f5w6fw6q 4515 4 admission admission NN cord-006870-f5w6fw6q 4515 5 GCS GCS NNP cord-006870-f5w6fw6q 4515 6 , , , cord-006870-f5w6fw6q 4515 7 APACHE APACHE NNP cord-006870-f5w6fw6q 4515 8 II II NNP cord-006870-f5w6fw6q 4515 9 score score NN cord-006870-f5w6fw6q 4515 10 , , , cord-006870-f5w6fw6q 4515 11 Fisher Fisher NNP cord-006870-f5w6fw6q 4515 12 and and CC cord-006870-f5w6fw6q 4515 13 Hunt Hunt NNP cord-006870-f5w6fw6q 4515 14 and and CC cord-006870-f5w6fw6q 4515 15 Hess Hess NNP cord-006870-f5w6fw6q 4515 16 ( ( -LRB- cord-006870-f5w6fw6q 4515 17 HH HH NNP cord-006870-f5w6fw6q 4515 18 ) ) -RRB- cord-006870-f5w6fw6q 4515 19 scores score NNS cord-006870-f5w6fw6q 4515 20 , , , cord-006870-f5w6fw6q 4515 21 AED AED NNP cord-006870-f5w6fw6q 4515 22 dosing dosing NN cord-006870-f5w6fw6q 4515 23 and and CC cord-006870-f5w6fw6q 4515 24 discharge discharge NN cord-006870-f5w6fw6q 4515 25 GOS GOS NNP cord-006870-f5w6fw6q 4515 26 were be VBD cord-006870-f5w6fw6q 4515 27 ascertained ascertain VBN cord-006870-f5w6fw6q 4515 28 by by IN cord-006870-f5w6fw6q 4515 29 chart chart NN cord-006870-f5w6fw6q 4515 30 review review NN cord-006870-f5w6fw6q 4515 31 . . . cord-006870-f5w6fw6q 4515 32 _SP cord-006870-f5w6fw6q 4516 1 Presence presence NN cord-006870-f5w6fw6q 4516 2 of of IN cord-006870-f5w6fw6q 4516 3 IIC IIC NNP cord-006870-f5w6fw6q 4516 4 patterns pattern NNS cord-006870-f5w6fw6q 4516 5 in in IN cord-006870-f5w6fw6q 4516 6 aSAH asah JJ cord-006870-f5w6fw6q 4516 7 independently independently RB cord-006870-f5w6fw6q 4516 8 predicts predict VBZ cord-006870-f5w6fw6q 4516 9 worse bad JJR cord-006870-f5w6fw6q 4516 10 neurologic neurologic JJ cord-006870-f5w6fw6q 4516 11 outcome outcome NN cord-006870-f5w6fw6q 4516 12 , , , cord-006870-f5w6fw6q 4516 13 although although IN cord-006870-f5w6fw6q 4516 14 maximum maximum JJ cord-006870-f5w6fw6q 4516 15 burden burden NN cord-006870-f5w6fw6q 4516 16 does do VBZ cord-006870-f5w6fw6q 4516 17 not not RB cord-006870-f5w6fw6q 4516 18 . . . cord-006870-f5w6fw6q 4517 1 Although although IN cord-006870-f5w6fw6q 4517 2 nearly nearly RB cord-006870-f5w6fw6q 4517 3 half half NN cord-006870-f5w6fw6q 4517 4 of of IN cord-006870-f5w6fw6q 4517 5 these these DT cord-006870-f5w6fw6q 4517 6 patients patient NNS cord-006870-f5w6fw6q 4517 7 receive receive VBP cord-006870-f5w6fw6q 4517 8 AED AED NNP cord-006870-f5w6fw6q 4517 9 treatment treatment NN cord-006870-f5w6fw6q 4517 10 , , , cord-006870-f5w6fw6q 4517 11 our -PRON- PRP$ cord-006870-f5w6fw6q 4517 12 data datum NNS cord-006870-f5w6fw6q 4517 13 suggest suggest VBP cord-006870-f5w6fw6q 4517 14 that that IN cord-006870-f5w6fw6q 4517 15 AED AED NNP cord-006870-f5w6fw6q 4517 16 treatment treatment NN cord-006870-f5w6fw6q 4517 17 may may MD cord-006870-f5w6fw6q 4517 18 not not RB cord-006870-f5w6fw6q 4517 19 influence influence VB cord-006870-f5w6fw6q 4517 20 outcome outcome NN cord-006870-f5w6fw6q 4517 21 . . . cord-006870-f5w6fw6q 4518 1 Prospective prospective JJ cord-006870-f5w6fw6q 4518 2 studies study NNS cord-006870-f5w6fw6q 4518 3 may may MD cord-006870-f5w6fw6q 4518 4 further further RB cord-006870-f5w6fw6q 4518 5 delineate delineate VB cord-006870-f5w6fw6q 4518 6 the the DT cord-006870-f5w6fw6q 4518 7 clinical clinical JJ cord-006870-f5w6fw6q 4518 8 risks risk NNS cord-006870-f5w6fw6q 4518 9 and and CC cord-006870-f5w6fw6q 4518 10 benefits benefit NNS cord-006870-f5w6fw6q 4518 11 of of IN cord-006870-f5w6fw6q 4518 12 AED AED NNP cord-006870-f5w6fw6q 4518 13 treatment treatment NN cord-006870-f5w6fw6q 4518 14 . . . cord-006870-f5w6fw6q 4519 1 Refractory refractory JJ cord-006870-f5w6fw6q 4519 2 status status NN cord-006870-f5w6fw6q 4519 3 epilepticus epilepticus NN cord-006870-f5w6fw6q 4519 4 ( ( -LRB- cord-006870-f5w6fw6q 4519 5 RSE RSE NNP cord-006870-f5w6fw6q 4519 6 ) ) -RRB- cord-006870-f5w6fw6q 4519 7 is be VBZ cord-006870-f5w6fw6q 4519 8 defined define VBN cord-006870-f5w6fw6q 4519 9 by by IN cord-006870-f5w6fw6q 4519 10 failure failure NN cord-006870-f5w6fw6q 4519 11 to to TO cord-006870-f5w6fw6q 4519 12 control control VB cord-006870-f5w6fw6q 4519 13 epileptic epileptic JJ cord-006870-f5w6fw6q 4519 14 activity activity NN cord-006870-f5w6fw6q 4519 15 after after IN cord-006870-f5w6fw6q 4519 16 the the DT cord-006870-f5w6fw6q 4519 17 administration administration NN cord-006870-f5w6fw6q 4519 18 of of IN cord-006870-f5w6fw6q 4519 19 1st 1st JJ cord-006870-f5w6fw6q 4519 20 and and CC cord-006870-f5w6fw6q 4519 21 2nd 2nd JJ cord-006870-f5w6fw6q 4519 22 line line NN cord-006870-f5w6fw6q 4519 23 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 4519 24 agents agent NNS cord-006870-f5w6fw6q 4519 25 . . . cord-006870-f5w6fw6q 4520 1 Mortality mortality NN cord-006870-f5w6fw6q 4520 2 associated associate VBN cord-006870-f5w6fw6q 4520 3 with with IN cord-006870-f5w6fw6q 4520 4 RSE RSE NNP cord-006870-f5w6fw6q 4520 5 has have VBZ cord-006870-f5w6fw6q 4520 6 been be VBN cord-006870-f5w6fw6q 4520 7 estimated estimate VBN cord-006870-f5w6fw6q 4520 8 to to TO cord-006870-f5w6fw6q 4520 9 be be VB cord-006870-f5w6fw6q 4520 10 around around RB cord-006870-f5w6fw6q 4520 11 23 23 CD cord-006870-f5w6fw6q 4520 12 - - SYM cord-006870-f5w6fw6q 4520 13 61 61 CD cord-006870-f5w6fw6q 4520 14 % % NN cord-006870-f5w6fw6q 4520 15 at at IN cord-006870-f5w6fw6q 4520 16 hospital hospital NN cord-006870-f5w6fw6q 4520 17 discharge discharge NN cord-006870-f5w6fw6q 4520 18 . . . cord-006870-f5w6fw6q 4521 1 We -PRON- PRP cord-006870-f5w6fw6q 4521 2 conducted conduct VBD cord-006870-f5w6fw6q 4521 3 this this DT cord-006870-f5w6fw6q 4521 4 study study NN cord-006870-f5w6fw6q 4521 5 to to TO cord-006870-f5w6fw6q 4521 6 analyze analyze VB cord-006870-f5w6fw6q 4521 7 trends trend NNS cord-006870-f5w6fw6q 4521 8 in in IN cord-006870-f5w6fw6q 4521 9 the the DT cord-006870-f5w6fw6q 4521 10 frequency frequency NN cord-006870-f5w6fw6q 4521 11 and and CC cord-006870-f5w6fw6q 4521 12 management management NN cord-006870-f5w6fw6q 4521 13 of of IN cord-006870-f5w6fw6q 4521 14 RSE RSE NNP cord-006870-f5w6fw6q 4521 15 . . . cord-006870-f5w6fw6q 4522 1 We -PRON- PRP cord-006870-f5w6fw6q 4522 2 conducted conduct VBD cord-006870-f5w6fw6q 4522 3 a a DT cord-006870-f5w6fw6q 4522 4 cross cross NN cord-006870-f5w6fw6q 4522 5 - - NNP cord-006870-f5w6fw6q 4522 6 Consortium Consortium NNP cord-006870-f5w6fw6q 4522 7 ( ( -LRB- cord-006870-f5w6fw6q 4522 8 UHC UHC NNP cord-006870-f5w6fw6q 4522 9 ) ) -RRB- cord-006870-f5w6fw6q 4522 10 database database NN cord-006870-f5w6fw6q 4522 11 from from IN cord-006870-f5w6fw6q 4522 12 2009 2009 CD cord-006870-f5w6fw6q 4522 13 to to IN cord-006870-f5w6fw6q 4522 14 2016 2016 CD cord-006870-f5w6fw6q 4522 15 . . . cord-006870-f5w6fw6q 4523 1 This this DT cord-006870-f5w6fw6q 4523 2 is be VBZ cord-006870-f5w6fw6q 4523 3 a a DT cord-006870-f5w6fw6q 4523 4 database database NN cord-006870-f5w6fw6q 4523 5 from from IN cord-006870-f5w6fw6q 4523 6 120 120 CD cord-006870-f5w6fw6q 4523 7 academic academic JJ cord-006870-f5w6fw6q 4523 8 medical medical JJ cord-006870-f5w6fw6q 4523 9 centers center NNS cord-006870-f5w6fw6q 4523 10 and and CC cord-006870-f5w6fw6q 4523 11 their -PRON- PRP$ cord-006870-f5w6fw6q 4523 12 299 299 CD cord-006870-f5w6fw6q 4523 13 affiliated affiliate VBN cord-006870-f5w6fw6q 4523 14 hospitals hospital NNS cord-006870-f5w6fw6q 4523 15 in in IN cord-006870-f5w6fw6q 4523 16 the the DT cord-006870-f5w6fw6q 4523 17 United United NNP cord-006870-f5w6fw6q 4523 18 States States NNP cord-006870-f5w6fw6q 4523 19 and and CC cord-006870-f5w6fw6q 4523 20 consists consist VBZ cord-006870-f5w6fw6q 4523 21 of of IN cord-006870-f5w6fw6q 4523 22 a a DT cord-006870-f5w6fw6q 4523 23 sample sample NN cord-006870-f5w6fw6q 4523 24 of of IN cord-006870-f5w6fw6q 4523 25 12,366,264 12,366,264 CD cord-006870-f5w6fw6q 4523 26 patients patient NNS cord-006870-f5w6fw6q 4523 27 . . . cord-006870-f5w6fw6q 4524 1 Data datum NNS cord-006870-f5w6fw6q 4524 2 including include VBG cord-006870-f5w6fw6q 4524 3 age age NN cord-006870-f5w6fw6q 4524 4 , , , cord-006870-f5w6fw6q 4524 5 sex sex NN cord-006870-f5w6fw6q 4524 6 , , , cord-006870-f5w6fw6q 4524 7 antiepileptics antiepileptic NNS cord-006870-f5w6fw6q 4524 8 ( ( -LRB- cord-006870-f5w6fw6q 4524 9 AED AED NNP cord-006870-f5w6fw6q 4524 10 ) ) -RRB- cord-006870-f5w6fw6q 4524 11 and and CC cord-006870-f5w6fw6q 4524 12 length length NN cord-006870-f5w6fw6q 4524 13 of of IN cord-006870-f5w6fw6q 4524 14 stay stay NN cord-006870-f5w6fw6q 4524 15 was be VBD cord-006870-f5w6fw6q 4524 16 collected collect VBN cord-006870-f5w6fw6q 4524 17 . . . cord-006870-f5w6fw6q 4525 1 Total total JJ cord-006870-f5w6fw6q 4525 2 mean mean JJ cord-006870-f5w6fw6q 4525 3 age age NN cord-006870-f5w6fw6q 4525 4 was be VBD cord-006870-f5w6fw6q 4525 5 52.4 52.4 CD cord-006870-f5w6fw6q 4525 6 years year NNS cord-006870-f5w6fw6q 4525 7 and and CC cord-006870-f5w6fw6q 4525 8 females female NNS cord-006870-f5w6fw6q 4525 9 were be VBD cord-006870-f5w6fw6q 4525 10 48.83 48.83 CD cord-006870-f5w6fw6q 4525 11 % % NN cord-006870-f5w6fw6q 4525 12 . . . cord-006870-f5w6fw6q 4526 1 There there EX cord-006870-f5w6fw6q 4526 2 was be VBD cord-006870-f5w6fw6q 4526 3 an an DT cord-006870-f5w6fw6q 4526 4 increasing increase VBG cord-006870-f5w6fw6q 4526 5 trend trend NN cord-006870-f5w6fw6q 4526 6 of of IN cord-006870-f5w6fw6q 4526 7 using use VBG cord-006870-f5w6fw6q 4526 8 lorazepam lorazepam NN cord-006870-f5w6fw6q 4526 9 as as IN cord-006870-f5w6fw6q 4526 10 the the DT cord-006870-f5w6fw6q 4526 11 first first JJ cord-006870-f5w6fw6q 4526 12 line line NN cord-006870-f5w6fw6q 4526 13 AED AED NNP cord-006870-f5w6fw6q 4526 14 ( ( -LRB- cord-006870-f5w6fw6q 4526 15 58.5 58.5 CD cord-006870-f5w6fw6q 4526 16 % % NN cord-006870-f5w6fw6q 4526 17 in in IN cord-006870-f5w6fw6q 4526 18 2009 2009 CD cord-006870-f5w6fw6q 4526 19 to to IN cord-006870-f5w6fw6q 4526 20 60.5 60.5 CD cord-006870-f5w6fw6q 4526 21 % % NN cord-006870-f5w6fw6q 4526 22 in in IN cord-006870-f5w6fw6q 4526 23 2016 2016 CD cord-006870-f5w6fw6q 4526 24 ) ) -RRB- cord-006870-f5w6fw6q 4526 25 and and CC cord-006870-f5w6fw6q 4526 26 a a DT cord-006870-f5w6fw6q 4526 27 decreasing decrease VBG cord-006870-f5w6fw6q 4526 28 trend trend NN cord-006870-f5w6fw6q 4526 29 was be VBD cord-006870-f5w6fw6q 4526 30 noted note VBN cord-006870-f5w6fw6q 4526 31 of of IN cord-006870-f5w6fw6q 4526 32 using use VBG cord-006870-f5w6fw6q 4526 33 midazolam midazolam NNP cord-006870-f5w6fw6q 4526 34 as as IN cord-006870-f5w6fw6q 4526 35 the the DT cord-006870-f5w6fw6q 4526 36 first first JJ cord-006870-f5w6fw6q 4526 37 line line NN cord-006870-f5w6fw6q 4526 38 AED AED NNP cord-006870-f5w6fw6q 4526 39 ( ( -LRB- cord-006870-f5w6fw6q 4526 40 62.9 62.9 CD cord-006870-f5w6fw6q 4526 41 % % NN cord-006870-f5w6fw6q 4526 42 in in IN cord-006870-f5w6fw6q 4526 43 2009 2009 CD cord-006870-f5w6fw6q 4526 44 AED AED NNP cord-006870-f5w6fw6q 4526 45 ( ( -LRB- cord-006870-f5w6fw6q 4526 46 62.9 62.9 CD cord-006870-f5w6fw6q 4526 47 % % NN cord-006870-f5w6fw6q 4526 48 in in IN cord-006870-f5w6fw6q 4526 49 to to IN cord-006870-f5w6fw6q 4526 50 55.4 55.4 CD cord-006870-f5w6fw6q 4526 51 % % NN cord-006870-f5w6fw6q 4526 52 in in IN cord-006870-f5w6fw6q 4526 53 2016 2016 CD cord-006870-f5w6fw6q 4526 54 . . . cord-006870-f5w6fw6q 4527 1 Leviteracetam Leviteracetam NNP cord-006870-f5w6fw6q 4527 2 was be VBD cord-006870-f5w6fw6q 4527 3 the the DT cord-006870-f5w6fw6q 4527 4 most most RBS cord-006870-f5w6fw6q 4527 5 common common JJ cord-006870-f5w6fw6q 4527 6 second second JJ cord-006870-f5w6fw6q 4527 7 line line NN cord-006870-f5w6fw6q 4527 8 AED AED NNP cord-006870-f5w6fw6q 4527 9 used use VBN cord-006870-f5w6fw6q 4527 10 throughout throughout IN cord-006870-f5w6fw6q 4527 11 all all DT cord-006870-f5w6fw6q 4527 12 years year NNS cord-006870-f5w6fw6q 4527 13 which which WDT cord-006870-f5w6fw6q 4527 14 was be VBD cord-006870-f5w6fw6q 4527 15 followed follow VBN cord-006870-f5w6fw6q 4527 16 by by IN cord-006870-f5w6fw6q 4527 17 propofol propofol NN cord-006870-f5w6fw6q 4527 18 followed follow VBN cord-006870-f5w6fw6q 4527 19 by by IN cord-006870-f5w6fw6q 4527 20 phenytoin phenytoin NNP cord-006870-f5w6fw6q 4527 21 / / SYM cord-006870-f5w6fw6q 4527 22 fosphenytoin fosphenytoin NNP cord-006870-f5w6fw6q 4527 23 . . . cord-006870-f5w6fw6q 4528 1 Mean mean JJ cord-006870-f5w6fw6q 4528 2 length length NN cord-006870-f5w6fw6q 4528 3 of of IN cord-006870-f5w6fw6q 4528 4 hospital hospital NN cord-006870-f5w6fw6q 4528 5 stay stay NN cord-006870-f5w6fw6q 4528 6 was be VBD cord-006870-f5w6fw6q 4528 7 10.8 10.8 CD cord-006870-f5w6fw6q 4528 8 days day NNS cord-006870-f5w6fw6q 4528 9 . . . cord-006870-f5w6fw6q 4529 1 Between between IN cord-006870-f5w6fw6q 4529 2 2009 2009 CD cord-006870-f5w6fw6q 4529 3 to to IN cord-006870-f5w6fw6q 4529 4 2016 2016 CD cord-006870-f5w6fw6q 4529 5 , , , cord-006870-f5w6fw6q 4529 6 the the DT cord-006870-f5w6fw6q 4529 7 proportion proportion NN cord-006870-f5w6fw6q 4529 8 of of IN cord-006870-f5w6fw6q 4529 9 hospitalized hospitalize VBN cord-006870-f5w6fw6q 4529 10 patients patient NNS cord-006870-f5w6fw6q 4529 11 in in IN cord-006870-f5w6fw6q 4529 12 the the DT cord-006870-f5w6fw6q 4529 13 United United NNP cord-006870-f5w6fw6q 4529 14 States States NNP cord-006870-f5w6fw6q 4529 15 diagnosed diagnose VBD cord-006870-f5w6fw6q 4529 16 with with IN cord-006870-f5w6fw6q 4529 17 RSE RSE NNP cord-006870-f5w6fw6q 4529 18 has have VBZ cord-006870-f5w6fw6q 4529 19 increased increase VBN cord-006870-f5w6fw6q 4529 20 . . . cord-006870-f5w6fw6q 4530 1 Lorazepam Lorazepam NNP cord-006870-f5w6fw6q 4530 2 and and CC cord-006870-f5w6fw6q 4530 3 leviteracetam leviteracetam NNP cord-006870-f5w6fw6q 4530 4 have have VBP cord-006870-f5w6fw6q 4530 5 been be VBN cord-006870-f5w6fw6q 4530 6 the the DT cord-006870-f5w6fw6q 4530 7 most most RBS cord-006870-f5w6fw6q 4530 8 common common JJ cord-006870-f5w6fw6q 4530 9 AEDs aed NNS cord-006870-f5w6fw6q 4530 10 used use VBN cord-006870-f5w6fw6q 4530 11 . . . cord-006870-f5w6fw6q 4531 1 Mean mean JJ cord-006870-f5w6fw6q 4531 2 length length NN cord-006870-f5w6fw6q 4531 3 of of IN cord-006870-f5w6fw6q 4531 4 hospital hospital NN cord-006870-f5w6fw6q 4531 5 stay stay NN cord-006870-f5w6fw6q 4531 6 has have VBZ cord-006870-f5w6fw6q 4531 7 not not RB cord-006870-f5w6fw6q 4531 8 changed change VBN cord-006870-f5w6fw6q 4531 9 . . . cord-006870-f5w6fw6q 4532 1 Status status NN cord-006870-f5w6fw6q 4532 2 epilepticus epilepticus NN cord-006870-f5w6fw6q 4532 3 is be VBZ cord-006870-f5w6fw6q 4532 4 associated associate VBN cord-006870-f5w6fw6q 4532 5 with with IN cord-006870-f5w6fw6q 4532 6 high high JJ cord-006870-f5w6fw6q 4532 7 risk risk NN cord-006870-f5w6fw6q 4532 8 of of IN cord-006870-f5w6fw6q 4532 9 multi multi JJ cord-006870-f5w6fw6q 4532 10 - - JJ cord-006870-f5w6fw6q 4532 11 organ organ JJ cord-006870-f5w6fw6q 4532 12 dysfunction dysfunction NN cord-006870-f5w6fw6q 4532 13 . . . cord-006870-f5w6fw6q 4533 1 Ketamine Ketamine NNP cord-006870-f5w6fw6q 4533 2 for for IN cord-006870-f5w6fw6q 4533 3 the the DT cord-006870-f5w6fw6q 4533 4 treatment treatment NN cord-006870-f5w6fw6q 4533 5 of of IN cord-006870-f5w6fw6q 4533 6 super super JJ cord-006870-f5w6fw6q 4533 7 refractory refractory JJ cord-006870-f5w6fw6q 4533 8 status status NN cord-006870-f5w6fw6q 4533 9 epilepticus epilepticus NN cord-006870-f5w6fw6q 4533 10 ( ( -LRB- cord-006870-f5w6fw6q 4533 11 SRSE SRSE NNP cord-006870-f5w6fw6q 4533 12 ) ) -RRB- cord-006870-f5w6fw6q 4533 13 has have VBZ cord-006870-f5w6fw6q 4533 14 the the DT cord-006870-f5w6fw6q 4533 15 benefit benefit NN cord-006870-f5w6fw6q 4533 16 of of IN cord-006870-f5w6fw6q 4533 17 a a DT cord-006870-f5w6fw6q 4533 18 different different JJ cord-006870-f5w6fw6q 4533 19 mechanism mechanism NN cord-006870-f5w6fw6q 4533 20 and and CC cord-006870-f5w6fw6q 4533 21 lack lack NN cord-006870-f5w6fw6q 4533 22 of of IN cord-006870-f5w6fw6q 4533 23 cardiac cardiac JJ cord-006870-f5w6fw6q 4533 24 depression depression NN cord-006870-f5w6fw6q 4533 25 when when WRB cord-006870-f5w6fw6q 4533 26 compared compare VBN cord-006870-f5w6fw6q 4533 27 with with IN cord-006870-f5w6fw6q 4533 28 other other JJ cord-006870-f5w6fw6q 4533 29 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4533 30 agents agent NNS cord-006870-f5w6fw6q 4533 31 . . . cord-006870-f5w6fw6q 4534 1 This this DT cord-006870-f5w6fw6q 4534 2 study study NN cord-006870-f5w6fw6q 4534 3 evaluated evaluate VBD cord-006870-f5w6fw6q 4534 4 the the DT cord-006870-f5w6fw6q 4534 5 improvement improvement NN cord-006870-f5w6fw6q 4534 6 in in IN cord-006870-f5w6fw6q 4534 7 Sequential Sequential NNP cord-006870-f5w6fw6q 4534 8 Organ Organ NNP cord-006870-f5w6fw6q 4534 9 Failure Failure NNP cord-006870-f5w6fw6q 4534 10 Assessment Assessment NNP cord-006870-f5w6fw6q 4534 11 ( ( -LRB- cord-006870-f5w6fw6q 4534 12 SOFA SOFA NNP cord-006870-f5w6fw6q 4534 13 ) ) -RRB- cord-006870-f5w6fw6q 4534 14 score score NN cord-006870-f5w6fw6q 4534 15 in in IN cord-006870-f5w6fw6q 4534 16 patients patient NNS cord-006870-f5w6fw6q 4534 17 treated treat VBN cord-006870-f5w6fw6q 4534 18 with with IN cord-006870-f5w6fw6q 4534 19 ketamine ketamine NN cord-006870-f5w6fw6q 4534 20 for for IN cord-006870-f5w6fw6q 4534 21 SRSE SRSE NNP cord-006870-f5w6fw6q 4534 22 . . . cord-006870-f5w6fw6q 4535 1 This this DT cord-006870-f5w6fw6q 4535 2 is be VBZ cord-006870-f5w6fw6q 4535 3 a a DT cord-006870-f5w6fw6q 4535 4 retrospective retrospective JJ cord-006870-f5w6fw6q 4535 5 study study NN cord-006870-f5w6fw6q 4535 6 of of IN cord-006870-f5w6fw6q 4535 7 patients patient NNS cord-006870-f5w6fw6q 4535 8 with with IN cord-006870-f5w6fw6q 4535 9 SRSE SRSE NNP cord-006870-f5w6fw6q 4535 10 from from IN cord-006870-f5w6fw6q 4535 11 2011 2011 CD cord-006870-f5w6fw6q 4535 12 to to IN cord-006870-f5w6fw6q 4535 13 2016 2016 CD cord-006870-f5w6fw6q 4535 14 . . . cord-006870-f5w6fw6q 4536 1 The the DT cord-006870-f5w6fw6q 4536 2 timing timing NN cord-006870-f5w6fw6q 4536 3 and and CC cord-006870-f5w6fw6q 4536 4 dosage dosage NN cord-006870-f5w6fw6q 4536 5 of of IN cord-006870-f5w6fw6q 4536 6 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4536 7 agents agent NNS cord-006870-f5w6fw6q 4536 8 used use VBN cord-006870-f5w6fw6q 4536 9 in in IN cord-006870-f5w6fw6q 4536 10 their -PRON- PRP$ cord-006870-f5w6fw6q 4536 11 treatment treatment NN cord-006870-f5w6fw6q 4536 12 were be VBD cord-006870-f5w6fw6q 4536 13 abstracted abstract VBN cord-006870-f5w6fw6q 4536 14 . . . cord-006870-f5w6fw6q 4537 1 SOFA sofa NN cord-006870-f5w6fw6q 4537 2 scores score NNS cord-006870-f5w6fw6q 4537 3 at at IN cord-006870-f5w6fw6q 4537 4 admission admission NN cord-006870-f5w6fw6q 4537 5 and and CC cord-006870-f5w6fw6q 4537 6 for for IN cord-006870-f5w6fw6q 4537 7 the the DT cord-006870-f5w6fw6q 4537 8 first first JJ cord-006870-f5w6fw6q 4537 9 6 6 CD cord-006870-f5w6fw6q 4537 10 days day NNS cord-006870-f5w6fw6q 4537 11 after after IN cord-006870-f5w6fw6q 4537 12 initiation initiation NN cord-006870-f5w6fw6q 4537 13 of of IN cord-006870-f5w6fw6q 4537 14 ketamine ketamine NN cord-006870-f5w6fw6q 4537 15 were be VBD cord-006870-f5w6fw6q 4537 16 calculated calculate VBN cord-006870-f5w6fw6q 4537 17 . . . cord-006870-f5w6fw6q 4538 1 The the DT cord-006870-f5w6fw6q 4538 2 presence presence NN cord-006870-f5w6fw6q 4538 3 of of IN cord-006870-f5w6fw6q 4538 4 shock shock NN cord-006870-f5w6fw6q 4538 5 prior prior RB cord-006870-f5w6fw6q 4538 6 to to IN cord-006870-f5w6fw6q 4538 7 initiation initiation NN cord-006870-f5w6fw6q 4538 8 of of IN cord-006870-f5w6fw6q 4538 9 ketamine ketamine NN cord-006870-f5w6fw6q 4538 10 included include VBD cord-006870-f5w6fw6q 4538 11 septic septic JJ cord-006870-f5w6fw6q 4538 12 shock shock NN cord-006870-f5w6fw6q 4538 13 and and CC cord-006870-f5w6fw6q 4538 14 cardiogenic cardiogenic JJ cord-006870-f5w6fw6q 4538 15 shock shock NN cord-006870-f5w6fw6q 4538 16 . . . cord-006870-f5w6fw6q 4539 1 Outcomes outcome NNS cord-006870-f5w6fw6q 4539 2 including include VBG cord-006870-f5w6fw6q 4539 3 mortality mortality NN cord-006870-f5w6fw6q 4539 4 , , , cord-006870-f5w6fw6q 4539 5 organ organ NN cord-006870-f5w6fw6q 4539 6 failure failure NN cord-006870-f5w6fw6q 4539 7 , , , cord-006870-f5w6fw6q 4539 8 and and CC cord-006870-f5w6fw6q 4539 9 hospital hospital NN cord-006870-f5w6fw6q 4539 10 associated associate VBN cord-006870-f5w6fw6q 4539 11 infections infection NNS cord-006870-f5w6fw6q 4539 12 ( ( -LRB- cord-006870-f5w6fw6q 4539 13 HAIs hai NNS cord-006870-f5w6fw6q 4539 14 ) ) -RRB- cord-006870-f5w6fw6q 4539 15 were be VBD cord-006870-f5w6fw6q 4539 16 also also RB cord-006870-f5w6fw6q 4539 17 recorded record VBN cord-006870-f5w6fw6q 4539 18 . . . cord-006870-f5w6fw6q 4540 1 A a DT cord-006870-f5w6fw6q 4540 2 total total NN cord-006870-f5w6fw6q 4540 3 of of IN cord-006870-f5w6fw6q 4540 4 47 47 CD cord-006870-f5w6fw6q 4540 5 patients patient NNS cord-006870-f5w6fw6q 4540 6 were be VBD cord-006870-f5w6fw6q 4540 7 treated treat VBN cord-006870-f5w6fw6q 4540 8 with with IN cord-006870-f5w6fw6q 4540 9 ketamine ketamine NN cord-006870-f5w6fw6q 4540 10 after after IN cord-006870-f5w6fw6q 4540 11 failure failure NN cord-006870-f5w6fw6q 4540 12 of of IN cord-006870-f5w6fw6q 4540 13 seizure seizure NN cord-006870-f5w6fw6q 4540 14 control control NN cord-006870-f5w6fw6q 4540 15 using use VBG cord-006870-f5w6fw6q 4540 16 other other JJ cord-006870-f5w6fw6q 4540 17 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4540 18 agents agent NNS cord-006870-f5w6fw6q 4540 19 . . . cord-006870-f5w6fw6q 4541 1 Seventeen seventeen CD cord-006870-f5w6fw6q 4541 2 ( ( -LRB- cord-006870-f5w6fw6q 4541 3 36.2 36.2 CD cord-006870-f5w6fw6q 4541 4 % % NN cord-006870-f5w6fw6q 4541 5 ) ) -RRB- cord-006870-f5w6fw6q 4541 6 had have VBD cord-006870-f5w6fw6q 4541 7 an an DT cord-006870-f5w6fw6q 4541 8 improvement improvement NN cord-006870-f5w6fw6q 4541 9 of of IN cord-006870-f5w6fw6q 4541 10 their -PRON- PRP$ cord-006870-f5w6fw6q 4541 11 SOFA sofa NN cord-006870-f5w6fw6q 4541 12 score score NN cord-006870-f5w6fw6q 4541 13 while while IN cord-006870-f5w6fw6q 4541 14 30 30 CD cord-006870-f5w6fw6q 4541 15 ( ( -LRB- cord-006870-f5w6fw6q 4541 16 63.8 63.8 CD cord-006870-f5w6fw6q 4541 17 % % NN cord-006870-f5w6fw6q 4541 18 ) ) -RRB- cord-006870-f5w6fw6q 4541 19 did do VBD cord-006870-f5w6fw6q 4541 20 not not RB cord-006870-f5w6fw6q 4541 21 . . . cord-006870-f5w6fw6q 4542 1 The the DT cord-006870-f5w6fw6q 4542 2 median median JJ cord-006870-f5w6fw6q 4542 3 SOFA sofa NN cord-006870-f5w6fw6q 4542 4 score score NN cord-006870-f5w6fw6q 4542 5 on on IN cord-006870-f5w6fw6q 4542 6 admission admission NN cord-006870-f5w6fw6q 4542 7 was be VBD cord-006870-f5w6fw6q 4542 8 5 5 CD cord-006870-f5w6fw6q 4543 1 ( ( -LRB- cord-006870-f5w6fw6q 4543 2 IQR IQR NNP cord-006870-f5w6fw6q 4543 3 4 4 CD cord-006870-f5w6fw6q 4543 4 - - SYM cord-006870-f5w6fw6q 4543 5 6 6 CD cord-006870-f5w6fw6q 4543 6 ) ) -RRB- cord-006870-f5w6fw6q 4543 7 for for IN cord-006870-f5w6fw6q 4543 8 those those DT cord-006870-f5w6fw6q 4543 9 who who WP cord-006870-f5w6fw6q 4543 10 had have VBD cord-006870-f5w6fw6q 4543 11 an an DT cord-006870-f5w6fw6q 4543 12 improvement improvement NN cord-006870-f5w6fw6q 4543 13 and and CC cord-006870-f5w6fw6q 4543 14 6 6 CD cord-006870-f5w6fw6q 4543 15 ( ( -LRB- cord-006870-f5w6fw6q 4543 16 IQR IQR NNP cord-006870-f5w6fw6q 4543 17 6 6 CD cord-006870-f5w6fw6q 4543 18 - - SYM cord-006870-f5w6fw6q 4543 19 8 8 CD cord-006870-f5w6fw6q 4543 20 ) ) -RRB- cord-006870-f5w6fw6q 4543 21 for for IN cord-006870-f5w6fw6q 4543 22 those those DT cord-006870-f5w6fw6q 4543 23 who who WP cord-006870-f5w6fw6q 4543 24 did do VBD cord-006870-f5w6fw6q 4543 25 not not RB cord-006870-f5w6fw6q 4543 26 ( ( -LRB- cord-006870-f5w6fw6q 4543 27 p=0.11 p=0.11 NNP cord-006870-f5w6fw6q 4543 28 ) ) -RRB- cord-006870-f5w6fw6q 4543 29 . . . cord-006870-f5w6fw6q 4544 1 Cardiac cardiac JJ cord-006870-f5w6fw6q 4544 2 arrest arrest NN cord-006870-f5w6fw6q 4544 3 was be VBD cord-006870-f5w6fw6q 4544 4 the the DT cord-006870-f5w6fw6q 4544 5 etiology etiology NN cord-006870-f5w6fw6q 4544 6 of of IN cord-006870-f5w6fw6q 4544 7 SRSE SRSE NNP cord-006870-f5w6fw6q 4544 8 for for IN cord-006870-f5w6fw6q 4544 9 6 6 CD cord-006870-f5w6fw6q 4544 10 ( ( -LRB- cord-006870-f5w6fw6q 4544 11 37.5 37.5 CD cord-006870-f5w6fw6q 4544 12 % % NN cord-006870-f5w6fw6q 4544 13 ) ) -RRB- cord-006870-f5w6fw6q 4544 14 patients patient NNS cord-006870-f5w6fw6q 4544 15 who who WP cord-006870-f5w6fw6q 4544 16 improved improve VBD cord-006870-f5w6fw6q 4544 17 vs. vs. CC cord-006870-f5w6fw6q 4544 18 10 10 CD cord-006870-f5w6fw6q 4544 19 ( ( -LRB- cord-006870-f5w6fw6q 4544 20 62.5 62.5 CD cord-006870-f5w6fw6q 4544 21 % % NN cord-006870-f5w6fw6q 4544 22 ) ) -RRB- cord-006870-f5w6fw6q 4544 23 patients patient NNS cord-006870-f5w6fw6q 4544 24 who who WP cord-006870-f5w6fw6q 4544 25 did do VBD cord-006870-f5w6fw6q 4544 26 not not RB cord-006870-f5w6fw6q 4544 27 ( ( -LRB- cord-006870-f5w6fw6q 4544 28 p=0.89 p=0.89 NNP cord-006870-f5w6fw6q 4544 29 ) ) -RRB- cord-006870-f5w6fw6q 4544 30 . . . cord-006870-f5w6fw6q 4545 1 Patients patient NNS cord-006870-f5w6fw6q 4545 2 required require VBD cord-006870-f5w6fw6q 4545 3 0 0 CD cord-006870-f5w6fw6q 4545 4 to to IN cord-006870-f5w6fw6q 4545 5 3 3 CD cord-006870-f5w6fw6q 4545 6 vasopressors vasopressor NNS cord-006870-f5w6fw6q 4545 7 for for IN cord-006870-f5w6fw6q 4545 8 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 4545 9 support support NN cord-006870-f5w6fw6q 4545 10 , , , cord-006870-f5w6fw6q 4545 11 with with IN cord-006870-f5w6fw6q 4545 12 less less RBR cord-006870-f5w6fw6q 4545 13 needed need VBN cord-006870-f5w6fw6q 4545 14 for for IN cord-006870-f5w6fw6q 4545 15 those those DT cord-006870-f5w6fw6q 4545 16 who who WP cord-006870-f5w6fw6q 4545 17 had have VBD cord-006870-f5w6fw6q 4545 18 an an DT cord-006870-f5w6fw6q 4545 19 improvement improvement NN cord-006870-f5w6fw6q 4545 20 ( ( -LRB- cord-006870-f5w6fw6q 4545 21 p=0.02 p=0.02 NN cord-006870-f5w6fw6q 4545 22 ) ) -RRB- cord-006870-f5w6fw6q 4545 23 . . . cord-006870-f5w6fw6q 4546 1 There there EX cord-006870-f5w6fw6q 4546 2 was be VBD cord-006870-f5w6fw6q 4546 3 a a DT cord-006870-f5w6fw6q 4546 4 higher high JJR cord-006870-f5w6fw6q 4546 5 rate rate NN cord-006870-f5w6fw6q 4546 6 of of IN cord-006870-f5w6fw6q 4546 7 HAIs hai NNS cord-006870-f5w6fw6q 4546 8 in in IN cord-006870-f5w6fw6q 4546 9 patient patient NN cord-006870-f5w6fw6q 4546 10 who who WP cord-006870-f5w6fw6q 4546 11 did do VBD cord-006870-f5w6fw6q 4546 12 not not RB cord-006870-f5w6fw6q 4546 13 have have VB cord-006870-f5w6fw6q 4546 14 an an DT cord-006870-f5w6fw6q 4546 15 improvement improvement NN cord-006870-f5w6fw6q 4546 16 of of IN cord-006870-f5w6fw6q 4546 17 their -PRON- PRP$ cord-006870-f5w6fw6q 4546 18 SOFA sofa NN cord-006870-f5w6fw6q 4546 19 score score NN cord-006870-f5w6fw6q 4546 20 ( ( -LRB- cord-006870-f5w6fw6q 4546 21 p=0.04 p=0.04 NNP cord-006870-f5w6fw6q 4546 22 ) ) -RRB- cord-006870-f5w6fw6q 4546 23 . . . cord-006870-f5w6fw6q 4547 1 There there EX cord-006870-f5w6fw6q 4547 2 is be VBZ cord-006870-f5w6fw6q 4547 3 a a DT cord-006870-f5w6fw6q 4547 4 subset subset NN cord-006870-f5w6fw6q 4547 5 of of IN cord-006870-f5w6fw6q 4547 6 patients patient NNS cord-006870-f5w6fw6q 4547 7 treated treat VBN cord-006870-f5w6fw6q 4547 8 with with IN cord-006870-f5w6fw6q 4547 9 ketamine ketamine NN cord-006870-f5w6fw6q 4547 10 for for IN cord-006870-f5w6fw6q 4547 11 SRSE SRSE NNP cord-006870-f5w6fw6q 4547 12 who who WP cord-006870-f5w6fw6q 4547 13 have have VBP cord-006870-f5w6fw6q 4547 14 an an DT cord-006870-f5w6fw6q 4547 15 improvement improvement NN cord-006870-f5w6fw6q 4547 16 in in IN cord-006870-f5w6fw6q 4547 17 their -PRON- PRP$ cord-006870-f5w6fw6q 4547 18 SOFA sofa NN cord-006870-f5w6fw6q 4547 19 score score NN cord-006870-f5w6fw6q 4547 20 , , , cord-006870-f5w6fw6q 4547 21 require require VBP cord-006870-f5w6fw6q 4547 22 less less JJR cord-006870-f5w6fw6q 4547 23 vasopressor vasopressor NN cord-006870-f5w6fw6q 4547 24 support support NN cord-006870-f5w6fw6q 4547 25 , , , cord-006870-f5w6fw6q 4547 26 and and CC cord-006870-f5w6fw6q 4547 27 have have VBP cord-006870-f5w6fw6q 4547 28 a a DT cord-006870-f5w6fw6q 4547 29 lower low JJR cord-006870-f5w6fw6q 4547 30 rate rate NN cord-006870-f5w6fw6q 4547 31 of of IN cord-006870-f5w6fw6q 4547 32 HAIs hai NNS cord-006870-f5w6fw6q 4547 33 . . . cord-006870-f5w6fw6q 4548 1 Further further JJ cord-006870-f5w6fw6q 4548 2 studies study NNS cord-006870-f5w6fw6q 4548 3 are be VBP cord-006870-f5w6fw6q 4548 4 needed need VBN cord-006870-f5w6fw6q 4548 5 to to TO cord-006870-f5w6fw6q 4548 6 better better RB cord-006870-f5w6fw6q 4548 7 understand understand VB cord-006870-f5w6fw6q 4548 8 which which WDT cord-006870-f5w6fw6q 4548 9 patient patient JJ cord-006870-f5w6fw6q 4548 10 population population NN cord-006870-f5w6fw6q 4548 11 may may MD cord-006870-f5w6fw6q 4548 12 most most RBS cord-006870-f5w6fw6q 4548 13 benefit benefit VB cord-006870-f5w6fw6q 4548 14 from from IN cord-006870-f5w6fw6q 4548 15 the the DT cord-006870-f5w6fw6q 4548 16 use use NN cord-006870-f5w6fw6q 4548 17 of of IN cord-006870-f5w6fw6q 4548 18 ketamine ketamine NN cord-006870-f5w6fw6q 4548 19 for for IN cord-006870-f5w6fw6q 4548 20 treatment treatment NN cord-006870-f5w6fw6q 4548 21 of of IN cord-006870-f5w6fw6q 4548 22 SRSE SRSE NNP cord-006870-f5w6fw6q 4548 23 . . . cord-006870-f5w6fw6q 4549 1 The the DT cord-006870-f5w6fw6q 4549 2 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4549 3 EEG EEG NNP cord-006870-f5w6fw6q 4549 4 System System NNP cord-006870-f5w6fw6q 4549 5 ( ( -LRB- cord-006870-f5w6fw6q 4549 6 CES CES NNP cord-006870-f5w6fw6q 4549 7 ) ) -RRB- cord-006870-f5w6fw6q 4549 8 is be VBZ cord-006870-f5w6fw6q 4549 9 a a DT cord-006870-f5w6fw6q 4549 10 novel novel JJ cord-006870-f5w6fw6q 4549 11 8 8 CD cord-006870-f5w6fw6q 4549 12 channel channel NN cord-006870-f5w6fw6q 4549 13 EEG EEG NNP cord-006870-f5w6fw6q 4549 14 device device NN cord-006870-f5w6fw6q 4549 15 with with IN cord-006870-f5w6fw6q 4549 16 instant instant JJ cord-006870-f5w6fw6q 4549 17 sonification sonification NN cord-006870-f5w6fw6q 4549 18 and and CC cord-006870-f5w6fw6q 4549 19 visual visual JJ cord-006870-f5w6fw6q 4549 20 display display NN cord-006870-f5w6fw6q 4549 21 capability capability NN cord-006870-f5w6fw6q 4549 22 that that WDT cord-006870-f5w6fw6q 4549 23 can can MD cord-006870-f5w6fw6q 4549 24 be be VB cord-006870-f5w6fw6q 4549 25 set set VBN cord-006870-f5w6fw6q 4549 26 up up RP cord-006870-f5w6fw6q 4549 27 quickly quickly RB cord-006870-f5w6fw6q 4549 28 without without IN cord-006870-f5w6fw6q 4549 29 an an DT cord-006870-f5w6fw6q 4549 30 EEG EEG NNP cord-006870-f5w6fw6q 4549 31 technician technician NN cord-006870-f5w6fw6q 4549 32 . . . cord-006870-f5w6fw6q 4550 1 We -PRON- PRP cord-006870-f5w6fw6q 4550 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 4550 3 that that IN cord-006870-f5w6fw6q 4550 4 by by IN cord-006870-f5w6fw6q 4550 5 using use VBG cord-006870-f5w6fw6q 4550 6 CES CES NNP cord-006870-f5w6fw6q 4550 7 , , , cord-006870-f5w6fw6q 4550 8 we -PRON- PRP cord-006870-f5w6fw6q 4550 9 can can MD cord-006870-f5w6fw6q 4550 10 decrease decrease VB cord-006870-f5w6fw6q 4550 11 time time NN cord-006870-f5w6fw6q 4550 12 to to IN cord-006870-f5w6fw6q 4550 13 EEG EEG NNP cord-006870-f5w6fw6q 4550 14 acquisition acquisition NN cord-006870-f5w6fw6q 4550 15 and and CC cord-006870-f5w6fw6q 4550 16 improve improve VB cord-006870-f5w6fw6q 4550 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 4550 18 and and CC cord-006870-f5w6fw6q 4550 19 treatment treatment NN cord-006870-f5w6fw6q 4550 20 decisions decision NNS cord-006870-f5w6fw6q 4550 21 in in IN cord-006870-f5w6fw6q 4550 22 suspected suspect VBN cord-006870-f5w6fw6q 4550 23 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 4550 24 seizures seizure NNS cord-006870-f5w6fw6q 4550 25 ( ( -LRB- cord-006870-f5w6fw6q 4550 26 NCS NCS NNP cord-006870-f5w6fw6q 4550 27 ) ) -RRB- cord-006870-f5w6fw6q 4550 28 . . . cord-006870-f5w6fw6q 4551 1 Adult adult JJ cord-006870-f5w6fw6q 4551 2 ICU ICU NNP cord-006870-f5w6fw6q 4551 3 patients patient NNS cord-006870-f5w6fw6q 4551 4 ( ( -LRB- cord-006870-f5w6fw6q 4551 5 GCS GCS NNP cord-006870-f5w6fw6q 4551 6 < < XX cord-006870-f5w6fw6q 4551 7 12 12 CD cord-006870-f5w6fw6q 4551 8 ) ) -RRB- cord-006870-f5w6fw6q 4551 9 who who WP cord-006870-f5w6fw6q 4551 10 had have VBD cord-006870-f5w6fw6q 4551 11 continuous continuous JJ cord-006870-f5w6fw6q 4551 12 EEG EEG NNP cord-006870-f5w6fw6q 4551 13 ( ( -LRB- cord-006870-f5w6fw6q 4551 14 cEEG ceeg JJ cord-006870-f5w6fw6q 4551 15 ) ) -RRB- cord-006870-f5w6fw6q 4551 16 as as IN cord-006870-f5w6fw6q 4551 17 part part NN cord-006870-f5w6fw6q 4551 18 of of IN cord-006870-f5w6fw6q 4551 19 clinical clinical JJ cord-006870-f5w6fw6q 4551 20 care care NN cord-006870-f5w6fw6q 4551 21 were be VBD cord-006870-f5w6fw6q 4551 22 enrolled enrol VBN cord-006870-f5w6fw6q 4551 23 . . . cord-006870-f5w6fw6q 4552 1 Once once RB cord-006870-f5w6fw6q 4552 2 cEEG ceeg JJ cord-006870-f5w6fw6q 4552 3 was be VBD cord-006870-f5w6fw6q 4552 4 ordered order VBN cord-006870-f5w6fw6q 4552 5 , , , cord-006870-f5w6fw6q 4552 6 consent consent NN cord-006870-f5w6fw6q 4552 7 was be VBD cord-006870-f5w6fw6q 4552 8 obtained obtain VBN cord-006870-f5w6fw6q 4552 9 and and CC cord-006870-f5w6fw6q 4552 10 CES CES NNP cord-006870-f5w6fw6q 4552 11 was be VBD cord-006870-f5w6fw6q 4552 12 placed place VBN cord-006870-f5w6fw6q 4552 13 by by IN cord-006870-f5w6fw6q 4552 14 the the DT cord-006870-f5w6fw6q 4552 15 treating treat VBG cord-006870-f5w6fw6q 4552 16 physician physician NN cord-006870-f5w6fw6q 4552 17 ( ( -LRB- cord-006870-f5w6fw6q 4552 18 n=7 n=7 NNS cord-006870-f5w6fw6q 4552 19 ) ) -RRB- cord-006870-f5w6fw6q 4552 20 who who WP cord-006870-f5w6fw6q 4552 21 listened listen VBD cord-006870-f5w6fw6q 4552 22 to to IN cord-006870-f5w6fw6q 4552 23 the the DT cord-006870-f5w6fw6q 4552 24 left left JJ cord-006870-f5w6fw6q 4552 25 / / SYM cord-006870-f5w6fw6q 4552 26 right right JJ cord-006870-f5w6fw6q 4552 27 hemisphere hemisphere NN cord-006870-f5w6fw6q 4552 28 signals signal NNS cord-006870-f5w6fw6q 4552 29 for for IN cord-006870-f5w6fw6q 4552 30 30 30 CD cord-006870-f5w6fw6q 4552 31 seconds second NNS cord-006870-f5w6fw6q 4552 32 each each DT cord-006870-f5w6fw6q 4552 33 . . . cord-006870-f5w6fw6q 4553 1 Suspicion suspicion NN cord-006870-f5w6fw6q 4553 2 for for IN cord-006870-f5w6fw6q 4553 3 seizure seizure NN cord-006870-f5w6fw6q 4553 4 ( ( -LRB- cord-006870-f5w6fw6q 4553 5 1 1 CD cord-006870-f5w6fw6q 4553 6 = = SYM cord-006870-f5w6fw6q 4553 7 low low NN cord-006870-f5w6fw6q 4553 8 , , , cord-006870-f5w6fw6q 4553 9 5 5 CD cord-006870-f5w6fw6q 4553 10 = = SYM cord-006870-f5w6fw6q 4553 11 high high NN cord-006870-f5w6fw6q 4553 12 ) ) -RRB- cord-006870-f5w6fw6q 4553 13 and and CC cord-006870-f5w6fw6q 4553 14 decision decision NN cord-006870-f5w6fw6q 4553 15 to to TO cord-006870-f5w6fw6q 4553 16 treat treat VB cord-006870-f5w6fw6q 4553 17 ( ( -LRB- cord-006870-f5w6fw6q 4553 18 yes yes UH cord-006870-f5w6fw6q 4553 19 / / , cord-006870-f5w6fw6q 4553 20 no no UH cord-006870-f5w6fw6q 4553 21 / / , cord-006870-f5w6fw6q 4553 22 not not RB cord-006870-f5w6fw6q 4553 23 sure sure JJ cord-006870-f5w6fw6q 4553 24 ) ) -RRB- cord-006870-f5w6fw6q 4553 25 were be VBD cord-006870-f5w6fw6q 4553 26 rated rate VBN cord-006870-f5w6fw6q 4553 27 pre pre JJ cord-006870-f5w6fw6q 4553 28 - - JJ cord-006870-f5w6fw6q 4553 29 and and CC cord-006870-f5w6fw6q 4553 30 post post JJ cord-006870-f5w6fw6q 4553 31 - - JJ cord-006870-f5w6fw6q 4553 32 sonification sonification NN cord-006870-f5w6fw6q 4553 33 . . . cord-006870-f5w6fw6q 4554 1 Three three CD cord-006870-f5w6fw6q 4554 2 blinded blinded JJ cord-006870-f5w6fw6q 4554 3 epileptologists epileptologist NNS cord-006870-f5w6fw6q 4554 4 compared compare VBN cord-006870-f5w6fw6q 4554 5 accuracy accuracy NN cord-006870-f5w6fw6q 4554 6 of of IN cord-006870-f5w6fw6q 4554 7 sonification sonification NN cord-006870-f5w6fw6q 4554 8 with with IN cord-006870-f5w6fw6q 4554 9 visual visual JJ cord-006870-f5w6fw6q 4554 10 CES CES NNP cord-006870-f5w6fw6q 4554 11 EEG EEG NNP cord-006870-f5w6fw6q 4554 12 . . . cord-006870-f5w6fw6q 4555 1 Outcomes outcome NNS cord-006870-f5w6fw6q 4555 2 were be VBD cord-006870-f5w6fw6q 4555 3 difference difference NN cord-006870-f5w6fw6q 4555 4 in in IN cord-006870-f5w6fw6q 4555 5 time time NN cord-006870-f5w6fw6q 4555 6 to to IN cord-006870-f5w6fw6q 4555 7 EEG EEG NNP cord-006870-f5w6fw6q 4555 8 acquisition acquisition NN cord-006870-f5w6fw6q 4555 9 , , , cord-006870-f5w6fw6q 4555 10 change change NN cord-006870-f5w6fw6q 4555 11 in in IN cord-006870-f5w6fw6q 4555 12 suspicion suspicion NN cord-006870-f5w6fw6q 4555 13 for for IN cord-006870-f5w6fw6q 4555 14 seizure seizure NN cord-006870-f5w6fw6q 4555 15 and and CC cord-006870-f5w6fw6q 4555 16 decision decision NN cord-006870-f5w6fw6q 4555 17 to to TO cord-006870-f5w6fw6q 4555 18 treat treat VB cord-006870-f5w6fw6q 4555 19 , , , cord-006870-f5w6fw6q 4555 20 and and CC cord-006870-f5w6fw6q 4555 21 ease ease NN cord-006870-f5w6fw6q 4555 22 of of IN cord-006870-f5w6fw6q 4555 23 use use NN cord-006870-f5w6fw6q 4555 24 ( ( -LRB- cord-006870-f5w6fw6q 4555 25 1 1 CD cord-006870-f5w6fw6q 4555 26 = = SYM cord-006870-f5w6fw6q 4555 27 challenging challenging NN cord-006870-f5w6fw6q 4555 28 ; ; : cord-006870-f5w6fw6q 4555 29 5 5 CD cord-006870-f5w6fw6q 4555 30 = = SYM cord-006870-f5w6fw6q 4555 31 easy easy NN cord-006870-f5w6fw6q 4555 32 ) ) -RRB- cord-006870-f5w6fw6q 4555 33 . . . cord-006870-f5w6fw6q 4556 1 35 35 CD cord-006870-f5w6fw6q 4556 2 patients patient NNS cord-006870-f5w6fw6q 4556 3 ( ( -LRB- cord-006870-f5w6fw6q 4556 4 mean mean VB cord-006870-f5w6fw6q 4556 5 age age NN cord-006870-f5w6fw6q 4556 6 61 61 CD cord-006870-f5w6fw6q 4557 1 + + CC cord-006870-f5w6fw6q 4557 2 /-18 /-18 NNP cord-006870-f5w6fw6q 4557 3 , , , cord-006870-f5w6fw6q 4557 4 median median JJ cord-006870-f5w6fw6q 4557 5 GCS GCS NNP cord-006870-f5w6fw6q 4557 6 of of IN cord-006870-f5w6fw6q 4557 7 6 6 CD cord-006870-f5w6fw6q 4558 1 ( ( -LRB- cord-006870-f5w6fw6q 4558 2 IQR IQR NNP cord-006870-f5w6fw6q 4558 3 4 4 CD cord-006870-f5w6fw6q 4558 4 - - SYM cord-006870-f5w6fw6q 4558 5 8.5 8.5 CD cord-006870-f5w6fw6q 4558 6 ) ) -RRB- cord-006870-f5w6fw6q 4558 7 were be VBD cord-006870-f5w6fw6q 4558 8 enrolled enrol VBN cord-006870-f5w6fw6q 4558 9 from from IN cord-006870-f5w6fw6q 4558 10 7:00 7:00 CD cord-006870-f5w6fw6q 4558 11 AM am NN cord-006870-f5w6fw6q 4558 12 to to IN cord-006870-f5w6fw6q 4558 13 5:00 5:00 CD cord-006870-f5w6fw6q 4558 14 PM pm NN cord-006870-f5w6fw6q 4558 15 . . . cord-006870-f5w6fw6q 4559 1 Start start NN cord-006870-f5w6fw6q 4559 2 of of IN cord-006870-f5w6fw6q 4559 3 EEG EEG NNP cord-006870-f5w6fw6q 4559 4 acquisition acquisition NN cord-006870-f5w6fw6q 4559 5 was be VBD cord-006870-f5w6fw6q 4559 6 significantly significantly RB cord-006870-f5w6fw6q 4559 7 faster fast JJR cord-006870-f5w6fw6q 4559 8 for for IN cord-006870-f5w6fw6q 4559 9 CES CES NNP cord-006870-f5w6fw6q 4559 10 ( ( -LRB- cord-006870-f5w6fw6q 4559 11 23 23 CD cord-006870-f5w6fw6q 4559 12 minutes minute NNS cord-006870-f5w6fw6q 4559 13 ( ( -LRB- cord-006870-f5w6fw6q 4559 14 IQR IQR NNP cord-006870-f5w6fw6q 4559 15 14 14 CD cord-006870-f5w6fw6q 4559 16 - - SYM cord-006870-f5w6fw6q 4559 17 46 46 CD cord-006870-f5w6fw6q 4559 18 ) ) -RRB- cord-006870-f5w6fw6q 4559 19 vs vs IN cord-006870-f5w6fw6q 4559 20 145 145 CD cord-006870-f5w6fw6q 4559 21 minutes minute NNS cord-006870-f5w6fw6q 4559 22 ( ( -LRB- cord-006870-f5w6fw6q 4559 23 IQR IQR NNP cord-006870-f5w6fw6q 4559 24 93 93 CD cord-006870-f5w6fw6q 4559 25 - - HYPH cord-006870-f5w6fw6q 4559 26 237 237 CD cord-006870-f5w6fw6q 4559 27 ) ) -RRB- cord-006870-f5w6fw6q 4559 28 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 4559 29 ) ) -RRB- cord-006870-f5w6fw6q 4559 30 , , , cord-006870-f5w6fw6q 4559 31 median median JJ cord-006870-f5w6fw6q 4559 32 difference difference NN cord-006870-f5w6fw6q 4559 33 86 86 CD cord-006870-f5w6fw6q 4559 34 minutes minute NNS cord-006870-f5w6fw6q 4560 1 ( ( -LRB- cord-006870-f5w6fw6q 4560 2 IQR IQR NNP cord-006870-f5w6fw6q 4560 3 60 60 CD cord-006870-f5w6fw6q 4560 4 - - SYM cord-006870-f5w6fw6q 4560 5 152 152 CD cord-006870-f5w6fw6q 4560 6 ) ) -RRB- cord-006870-f5w6fw6q 4560 7 . . . cord-006870-f5w6fw6q 4561 1 One one CD cord-006870-f5w6fw6q 4561 2 patient patient NN cord-006870-f5w6fw6q 4561 3 had have VBD cord-006870-f5w6fw6q 4561 4 NCS NCS NNP cord-006870-f5w6fw6q 4561 5 during during IN cord-006870-f5w6fw6q 4561 6 sonification sonification NN cord-006870-f5w6fw6q 4561 7 and and CC cord-006870-f5w6fw6q 4561 8 this this DT cord-006870-f5w6fw6q 4561 9 was be VBD cord-006870-f5w6fw6q 4561 10 accurately accurately RB cord-006870-f5w6fw6q 4561 11 identified identify VBN cord-006870-f5w6fw6q 4561 12 and and CC cord-006870-f5w6fw6q 4561 13 treated treat VBN cord-006870-f5w6fw6q 4561 14 . . . cord-006870-f5w6fw6q 4562 1 Low low JJ cord-006870-f5w6fw6q 4562 2 suspicion suspicion NN cord-006870-f5w6fw6q 4562 3 for for IN cord-006870-f5w6fw6q 4562 4 seizure seizure NN cord-006870-f5w6fw6q 4562 5 ( ( -LRB- cord-006870-f5w6fw6q 4562 6 1 1 CD cord-006870-f5w6fw6q 4562 7 ) ) -RRB- cord-006870-f5w6fw6q 4562 8 was be VBD cord-006870-f5w6fw6q 4562 9 more more RBR cord-006870-f5w6fw6q 4562 10 likely likely JJ cord-006870-f5w6fw6q 4562 11 postsonification postsonification NN cord-006870-f5w6fw6q 4562 12 ( ( -LRB- cord-006870-f5w6fw6q 4562 13 63 63 CD cord-006870-f5w6fw6q 4562 14 % % NN cord-006870-f5w6fw6q 4562 15 vs vs IN cord-006870-f5w6fw6q 4562 16 37 37 CD cord-006870-f5w6fw6q 4562 17 % % NN cord-006870-f5w6fw6q 4562 18 , , , cord-006870-f5w6fw6q 4562 19 p=0.029 p=0.029 NNP cord-006870-f5w6fw6q 4562 20 ) ) -RRB- cord-006870-f5w6fw6q 4562 21 . . . cord-006870-f5w6fw6q 4563 1 Treatment treatment NN cord-006870-f5w6fw6q 4563 2 decision decision NN cord-006870-f5w6fw6q 4563 3 changed change VBD cord-006870-f5w6fw6q 4563 4 in in IN cord-006870-f5w6fw6q 4563 5 40 40 CD cord-006870-f5w6fw6q 4563 6 % % NN cord-006870-f5w6fw6q 4563 7 after after IN cord-006870-f5w6fw6q 4563 8 sonification sonification NN cord-006870-f5w6fw6q 4563 9 , , , cord-006870-f5w6fw6q 4563 10 and and CC cord-006870-f5w6fw6q 4563 11 this this DT cord-006870-f5w6fw6q 4563 12 was be VBD cord-006870-f5w6fw6q 4563 13 in in IN cord-006870-f5w6fw6q 4563 14 the the DT cord-006870-f5w6fw6q 4563 15 correct correct JJ cord-006870-f5w6fw6q 4563 16 direction direction NN cord-006870-f5w6fw6q 4563 17 86 86 CD cord-006870-f5w6fw6q 4563 18 % % NN cord-006870-f5w6fw6q 4563 19 of of IN cord-006870-f5w6fw6q 4563 20 the the DT cord-006870-f5w6fw6q 4563 21 time time NN cord-006870-f5w6fw6q 4563 22 . . . cord-006870-f5w6fw6q 4564 1 Inappropriate inappropriate JJ cord-006870-f5w6fw6q 4564 2 decision decision NN cord-006870-f5w6fw6q 4564 3 to to TO cord-006870-f5w6fw6q 4564 4 treat treat VB cord-006870-f5w6fw6q 4564 5 decreased decrease VBD cord-006870-f5w6fw6q 4564 6 from from IN cord-006870-f5w6fw6q 4564 7 26 26 CD cord-006870-f5w6fw6q 4564 8 % % NN cord-006870-f5w6fw6q 4564 9 to to TO cord-006870-f5w6fw6q 4564 10 9 9 CD cord-006870-f5w6fw6q 4564 11 % % NN cord-006870-f5w6fw6q 4564 12 ( ( -LRB- cord-006870-f5w6fw6q 4564 13 p=0.07 p=0.07 NNP cord-006870-f5w6fw6q 4564 14 ) ) -RRB- cord-006870-f5w6fw6q 4564 15 . . . cord-006870-f5w6fw6q 4565 1 Negative negative JJ cord-006870-f5w6fw6q 4565 2 predictive predictive JJ cord-006870-f5w6fw6q 4565 3 value value NN cord-006870-f5w6fw6q 4565 4 was be VBD cord-006870-f5w6fw6q 4565 5 100 100 CD cord-006870-f5w6fw6q 4565 6 % % NN cord-006870-f5w6fw6q 4565 7 ( ( -LRB- cord-006870-f5w6fw6q 4565 8 95 95 CD cord-006870-f5w6fw6q 4565 9 % % NN cord-006870-f5w6fw6q 4565 10 CI CI NNP cord-006870-f5w6fw6q 4565 11 85 85 CD cord-006870-f5w6fw6q 4565 12 - - SYM cord-006870-f5w6fw6q 4565 13 100 100 CD cord-006870-f5w6fw6q 4565 14 % % NN cord-006870-f5w6fw6q 4565 15 ) ) -RRB- cord-006870-f5w6fw6q 4565 16 . . . cord-006870-f5w6fw6q 4566 1 CES CES NNP cord-006870-f5w6fw6q 4566 2 was be VBD cord-006870-f5w6fw6q 4566 3 consistently consistently RB cord-006870-f5w6fw6q 4566 4 rated rate VBN cord-006870-f5w6fw6q 4566 5 easy easy JJ cord-006870-f5w6fw6q 4566 6 to to TO cord-006870-f5w6fw6q 4566 7 use use VB cord-006870-f5w6fw6q 4566 8 . . . cord-006870-f5w6fw6q 4567 1 The the DT cord-006870-f5w6fw6q 4567 2 Ceribell Ceribell NNP cord-006870-f5w6fw6q 4567 3 EEG EEG NNP cord-006870-f5w6fw6q 4567 4 System System NNP cord-006870-f5w6fw6q 4567 5 is be VBZ cord-006870-f5w6fw6q 4567 6 easy easy JJ cord-006870-f5w6fw6q 4567 7 to to TO cord-006870-f5w6fw6q 4567 8 use use VB cord-006870-f5w6fw6q 4567 9 , , , cord-006870-f5w6fw6q 4567 10 speeds speed VBZ cord-006870-f5w6fw6q 4567 11 EEG EEG NNP cord-006870-f5w6fw6q 4567 12 acquisition acquisition NN cord-006870-f5w6fw6q 4567 13 , , , cord-006870-f5w6fw6q 4567 14 accurately accurately RB cord-006870-f5w6fw6q 4567 15 identifies identify VBZ cord-006870-f5w6fw6q 4567 16 NCS NCS NNP cord-006870-f5w6fw6q 4567 17 , , , cord-006870-f5w6fw6q 4567 18 and and CC cord-006870-f5w6fw6q 4567 19 enables enable VBZ cord-006870-f5w6fw6q 4567 20 appropriate appropriate JJ cord-006870-f5w6fw6q 4567 21 treatment treatment NN cord-006870-f5w6fw6q 4567 22 decisions decision NNS cord-006870-f5w6fw6q 4567 23 . . . cord-006870-f5w6fw6q 4568 1 It -PRON- PRP cord-006870-f5w6fw6q 4568 2 has have VBZ cord-006870-f5w6fw6q 4568 3 the the DT cord-006870-f5w6fw6q 4568 4 potential potential NN cord-006870-f5w6fw6q 4568 5 to to TO cord-006870-f5w6fw6q 4568 6 greatly greatly RB cord-006870-f5w6fw6q 4568 7 enhance enhance VB cord-006870-f5w6fw6q 4568 8 timely timely JJ cord-006870-f5w6fw6q 4568 9 diagnosis diagnosis NN cord-006870-f5w6fw6q 4568 10 and and CC cord-006870-f5w6fw6q 4568 11 treatment treatment NN cord-006870-f5w6fw6q 4568 12 of of IN cord-006870-f5w6fw6q 4568 13 NCS NCS NNP cord-006870-f5w6fw6q 4568 14 in in IN cord-006870-f5w6fw6q 4568 15 critically critically RB cord-006870-f5w6fw6q 4568 16 ill ill JJ cord-006870-f5w6fw6q 4568 17 patients patient NNS cord-006870-f5w6fw6q 4568 18 . . . cord-006870-f5w6fw6q 4569 1 The the DT cord-006870-f5w6fw6q 4569 2 aim aim NN cord-006870-f5w6fw6q 4569 3 of of IN cord-006870-f5w6fw6q 4569 4 the the DT cord-006870-f5w6fw6q 4569 5 study study NN cord-006870-f5w6fw6q 4569 6 was be VBD cord-006870-f5w6fw6q 4569 7 to to TO cord-006870-f5w6fw6q 4569 8 understand understand VB cord-006870-f5w6fw6q 4569 9 the the DT cord-006870-f5w6fw6q 4569 10 efficacy efficacy NN cord-006870-f5w6fw6q 4569 11 of of IN cord-006870-f5w6fw6q 4569 12 ketamine ketamine NN cord-006870-f5w6fw6q 4569 13 in in IN cord-006870-f5w6fw6q 4569 14 refractory refractory JJ cord-006870-f5w6fw6q 4569 15 status status NN cord-006870-f5w6fw6q 4569 16 epilepticus epilepticus NN cord-006870-f5w6fw6q 4569 17 and and CC cord-006870-f5w6fw6q 4569 18 identify identify VB cord-006870-f5w6fw6q 4569 19 the the DT cord-006870-f5w6fw6q 4569 20 underlying underlying JJ cord-006870-f5w6fw6q 4569 21 factors factor NNS cord-006870-f5w6fw6q 4569 22 affecting affect VBG cord-006870-f5w6fw6q 4569 23 the the DT cord-006870-f5w6fw6q 4569 24 effectiveness effectiveness NN cord-006870-f5w6fw6q 4569 25 of of IN cord-006870-f5w6fw6q 4569 26 ketamine ketamine NN cord-006870-f5w6fw6q 4569 27 . . . cord-006870-f5w6fw6q 4570 1 Moreover moreover RB cord-006870-f5w6fw6q 4570 2 , , , cord-006870-f5w6fw6q 4570 3 we -PRON- PRP cord-006870-f5w6fw6q 4570 4 also also RB cord-006870-f5w6fw6q 4570 5 studied study VBD cord-006870-f5w6fw6q 4570 6 the the DT cord-006870-f5w6fw6q 4570 7 rate rate NN cord-006870-f5w6fw6q 4570 8 of of IN cord-006870-f5w6fw6q 4570 9 complications complication NNS cord-006870-f5w6fw6q 4570 10 in in IN cord-006870-f5w6fw6q 4570 11 patients patient NNS cord-006870-f5w6fw6q 4570 12 who who WP cord-006870-f5w6fw6q 4570 13 underwent undergo VBD cord-006870-f5w6fw6q 4570 14 continuous continuous JJ cord-006870-f5w6fw6q 4570 15 midazolam midazolam NNP cord-006870-f5w6fw6q 4570 16 ketamine ketamine NN cord-006870-f5w6fw6q 4570 17 dual dual JJ cord-006870-f5w6fw6q 4570 18 therapy therapy NN cord-006870-f5w6fw6q 4570 19 for for IN cord-006870-f5w6fw6q 4570 20 treatment treatment NN cord-006870-f5w6fw6q 4570 21 of of IN cord-006870-f5w6fw6q 4570 22 refractory refractory JJ cord-006870-f5w6fw6q 4570 23 status status NN cord-006870-f5w6fw6q 4570 24 epilepticus epilepticus NN cord-006870-f5w6fw6q 4570 25 . . . cord-006870-f5w6fw6q 4571 1 This this DT cord-006870-f5w6fw6q 4571 2 is be VBZ cord-006870-f5w6fw6q 4571 3 retrospective retrospective JJ cord-006870-f5w6fw6q 4571 4 cohort cohort NN cord-006870-f5w6fw6q 4571 5 study study NN cord-006870-f5w6fw6q 4571 6 evaluating evaluate VBG cord-006870-f5w6fw6q 4571 7 the the DT cord-006870-f5w6fw6q 4571 8 efficacy efficacy NN cord-006870-f5w6fw6q 4571 9 of of IN cord-006870-f5w6fw6q 4571 10 ketamine ketamine NN cord-006870-f5w6fw6q 4571 11 in in IN cord-006870-f5w6fw6q 4571 12 patient patient NN cord-006870-f5w6fw6q 4571 13 with with IN cord-006870-f5w6fw6q 4571 14 refractory refractory JJ cord-006870-f5w6fw6q 4571 15 status status NN cord-006870-f5w6fw6q 4571 16 epilepticus epilepticus NN cord-006870-f5w6fw6q 4571 17 in in IN cord-006870-f5w6fw6q 4571 18 total total NN cord-006870-f5w6fw6q 4571 19 of of IN cord-006870-f5w6fw6q 4571 20 52 52 CD cord-006870-f5w6fw6q 4571 21 patients patient NNS cord-006870-f5w6fw6q 4571 22 admitted admit VBN cord-006870-f5w6fw6q 4571 23 to to IN cord-006870-f5w6fw6q 4571 24 University University NNP cord-006870-f5w6fw6q 4571 25 of of IN cord-006870-f5w6fw6q 4571 26 Maryland Maryland NNP cord-006870-f5w6fw6q 4571 27 Medical Medical NNP cord-006870-f5w6fw6q 4571 28 Center Center NNP cord-006870-f5w6fw6q 4571 29 in in IN cord-006870-f5w6fw6q 4571 30 either either DT cord-006870-f5w6fw6q 4571 31 neuro neuro NNP cord-006870-f5w6fw6q 4571 32 intensive intensive JJ cord-006870-f5w6fw6q 4571 33 care care NN cord-006870-f5w6fw6q 4571 34 unit unit NN cord-006870-f5w6fw6q 4571 35 /MICU /MICU . cord-006870-f5w6fw6q 4571 36 during during IN cord-006870-f5w6fw6q 4571 37 the the DT cord-006870-f5w6fw6q 4571 38 last last JJ cord-006870-f5w6fw6q 4571 39 five five CD cord-006870-f5w6fw6q 4571 40 years year NNS cord-006870-f5w6fw6q 4571 41 between between IN cord-006870-f5w6fw6q 4571 42 ( ( -LRB- cord-006870-f5w6fw6q 4571 43 2011 2011 CD cord-006870-f5w6fw6q 4571 44 - - SYM cord-006870-f5w6fw6q 4571 45 2016 2016 CD cord-006870-f5w6fw6q 4571 46 ) ) -RRB- cord-006870-f5w6fw6q 4571 47 . . . cord-006870-f5w6fw6q 4572 1 We -PRON- PRP cord-006870-f5w6fw6q 4572 2 established establish VBD cord-006870-f5w6fw6q 4572 3 a a DT cord-006870-f5w6fw6q 4572 4 standardized standardized JJ cord-006870-f5w6fw6q 4572 5 algorithm algorithm NN cord-006870-f5w6fw6q 4572 6 for for IN cord-006870-f5w6fw6q 4572 7 managing manage VBG cord-006870-f5w6fw6q 4572 8 refractory refractory JJ cord-006870-f5w6fw6q 4572 9 status status NN cord-006870-f5w6fw6q 4572 10 epilepticus epilepticus NN cord-006870-f5w6fw6q 4572 11 . . . cord-006870-f5w6fw6q 4573 1 Electrographic electrographic JJ cord-006870-f5w6fw6q 4573 2 and and CC cord-006870-f5w6fw6q 4573 3 clinical clinical JJ cord-006870-f5w6fw6q 4573 4 control control NN cord-006870-f5w6fw6q 4573 5 of of IN cord-006870-f5w6fw6q 4573 6 seizures seizure NNS cord-006870-f5w6fw6q 4573 7 was be VBD cord-006870-f5w6fw6q 4573 8 classified classify VBN cord-006870-f5w6fw6q 4573 9 into into IN cord-006870-f5w6fw6q 4573 10 four four CD cord-006870-f5w6fw6q 4573 11 groups group NNS cord-006870-f5w6fw6q 4573 12 : : : cord-006870-f5w6fw6q 4573 13 likely likely JJ cord-006870-f5w6fw6q 4573 14 response response NN cord-006870-f5w6fw6q 4573 15 , , , cord-006870-f5w6fw6q 4573 16 possible possible JJ cord-006870-f5w6fw6q 4573 17 response response NN cord-006870-f5w6fw6q 4573 18 , , , cord-006870-f5w6fw6q 4573 19 permanent permanent JJ cord-006870-f5w6fw6q 4573 20 response response NN cord-006870-f5w6fw6q 4573 21 and and CC cord-006870-f5w6fw6q 4573 22 no no DT cord-006870-f5w6fw6q 4573 23 response response NN cord-006870-f5w6fw6q 4573 24 reviewed review VBN cord-006870-f5w6fw6q 4573 25 by by IN cord-006870-f5w6fw6q 4573 26 a a DT cord-006870-f5w6fw6q 4573 27 team team NN cord-006870-f5w6fw6q 4573 28 of of IN cord-006870-f5w6fw6q 4573 29 epileptologist epileptologist NN cord-006870-f5w6fw6q 4573 30 and and CC cord-006870-f5w6fw6q 4573 31 neuro neuro NNP cord-006870-f5w6fw6q 4573 32 intensivist intensivist NN cord-006870-f5w6fw6q 4573 33 . . . cord-006870-f5w6fw6q 4574 1 The the DT cord-006870-f5w6fw6q 4574 2 effective effective JJ cord-006870-f5w6fw6q 4574 3 doses dose NNS cord-006870-f5w6fw6q 4574 4 of of IN cord-006870-f5w6fw6q 4574 5 ketamine ketamine NN cord-006870-f5w6fw6q 4574 6 to to TO cord-006870-f5w6fw6q 4574 7 abort abort VB cord-006870-f5w6fw6q 4574 8 RSE RSE NNP cord-006870-f5w6fw6q 4574 9 were be VBD cord-006870-f5w6fw6q 4574 10 studied study VBN cord-006870-f5w6fw6q 4574 11 . . . cord-006870-f5w6fw6q 4575 1 Complications complication NNS cord-006870-f5w6fw6q 4575 2 intensive intensive JJ cord-006870-f5w6fw6q 4575 3 care care NN cord-006870-f5w6fw6q 4575 4 unit unit NN cord-006870-f5w6fw6q 4575 5 stay stay VBP cord-006870-f5w6fw6q 4575 6 while while IN cord-006870-f5w6fw6q 4575 7 on on IN cord-006870-f5w6fw6q 4575 8 therapy therapy NN cord-006870-f5w6fw6q 4575 9 were be VBD cord-006870-f5w6fw6q 4575 10 reviewed review VBN cord-006870-f5w6fw6q 4575 11 . . . cord-006870-f5w6fw6q 4576 1 Of of IN cord-006870-f5w6fw6q 4576 2 the the DT cord-006870-f5w6fw6q 4576 3 52 52 CD cord-006870-f5w6fw6q 4576 4 patients patient NNS cord-006870-f5w6fw6q 4576 5 , , , cord-006870-f5w6fw6q 4576 6 29 29 CD cord-006870-f5w6fw6q 4576 7 were be VBD cord-006870-f5w6fw6q 4576 8 male male JJ cord-006870-f5w6fw6q 4576 9 , , , cord-006870-f5w6fw6q 4576 10 23 23 CD cord-006870-f5w6fw6q 4576 11 were be VBD cord-006870-f5w6fw6q 4576 12 female female JJ cord-006870-f5w6fw6q 4576 13 . . . cord-006870-f5w6fw6q 4577 1 22 22 CD cord-006870-f5w6fw6q 4577 2 % % NN cord-006870-f5w6fw6q 4577 3 of of IN cord-006870-f5w6fw6q 4577 4 the the DT cord-006870-f5w6fw6q 4577 5 patients patient NNS cord-006870-f5w6fw6q 4577 6 had have VBD cord-006870-f5w6fw6q 4577 7 cardiac cardiac JJ cord-006870-f5w6fw6q 4577 8 arrest arrest NN cord-006870-f5w6fw6q 4577 9 as as IN cord-006870-f5w6fw6q 4577 10 an an DT cord-006870-f5w6fw6q 4577 11 etiology etiology NN cord-006870-f5w6fw6q 4577 12 of of IN cord-006870-f5w6fw6q 4577 13 seizures seizure NNS cord-006870-f5w6fw6q 4577 14 . . . cord-006870-f5w6fw6q 4578 1 Median median JJ cord-006870-f5w6fw6q 4578 2 loading loading NN cord-006870-f5w6fw6q 4578 3 dose dose NN cord-006870-f5w6fw6q 4578 4 was be VBD cord-006870-f5w6fw6q 4578 5 1.5 1.5 CD cord-006870-f5w6fw6q 4578 6 mg mg NNP cord-006870-f5w6fw6q 4578 7 / / SYM cord-006870-f5w6fw6q 4578 8 kg kg NN cord-006870-f5w6fw6q 4578 9 , , , cord-006870-f5w6fw6q 4578 10 median median JJ cord-006870-f5w6fw6q 4578 11 maintenance maintenance NN cord-006870-f5w6fw6q 4578 12 dosage dosage NN cord-006870-f5w6fw6q 4578 13 was be VBD cord-006870-f5w6fw6q 4578 14 4 4 CD cord-006870-f5w6fw6q 4578 15 mg mg NNP cord-006870-f5w6fw6q 4578 16 / / SYM cord-006870-f5w6fw6q 4578 17 kg kg NNP cord-006870-f5w6fw6q 4578 18 / / SYM cord-006870-f5w6fw6q 4578 19 hr hr NN cord-006870-f5w6fw6q 4578 20 . . . cord-006870-f5w6fw6q 4579 1 25 25 CD cord-006870-f5w6fw6q 4579 2 % % NN cord-006870-f5w6fw6q 4579 3 of of IN cord-006870-f5w6fw6q 4579 4 the the DT cord-006870-f5w6fw6q 4579 5 patients patient NNS cord-006870-f5w6fw6q 4579 6 had have VBD cord-006870-f5w6fw6q 4579 7 no no DT cord-006870-f5w6fw6q 4579 8 response response NN cord-006870-f5w6fw6q 4579 9 to to IN cord-006870-f5w6fw6q 4579 10 ketamine ketamine NNP cord-006870-f5w6fw6q 4579 11 . . . cord-006870-f5w6fw6q 4580 1 75 75 CD cord-006870-f5w6fw6q 4580 2 % % NN cord-006870-f5w6fw6q 4580 3 were be VBD cord-006870-f5w6fw6q 4580 4 responsive responsive JJ cord-006870-f5w6fw6q 4580 5 to to IN cord-006870-f5w6fw6q 4580 6 ketamine ketamine NN cord-006870-f5w6fw6q 4580 7 of of IN cord-006870-f5w6fw6q 4580 8 which which WDT cord-006870-f5w6fw6q 4580 9 , , , cord-006870-f5w6fw6q 4580 10 12 12 CD cord-006870-f5w6fw6q 4580 11 patients patient NNS cord-006870-f5w6fw6q 4580 12 had have VBD cord-006870-f5w6fw6q 4580 13 likely likely JJ cord-006870-f5w6fw6q 4580 14 response response NN cord-006870-f5w6fw6q 4580 15 to to IN cord-006870-f5w6fw6q 4580 16 ketamine ketamine NN cord-006870-f5w6fw6q 4580 17 , , , cord-006870-f5w6fw6q 4580 18 28 28 CD cord-006870-f5w6fw6q 4580 19 patients patient NNS cord-006870-f5w6fw6q 4580 20 had have VBD cord-006870-f5w6fw6q 4580 21 possible possible JJ cord-006870-f5w6fw6q 4580 22 response.38.5 response.38.5 NNP cord-006870-f5w6fw6q 4580 23 % % NN cord-006870-f5w6fw6q 4580 24 of of IN cord-006870-f5w6fw6q 4580 25 the the DT cord-006870-f5w6fw6q 4580 26 patients patient NNS cord-006870-f5w6fw6q 4580 27 had have VBD cord-006870-f5w6fw6q 4580 28 permanent permanent JJ cord-006870-f5w6fw6q 4580 29 response response NN cord-006870-f5w6fw6q 4580 30 to to IN cord-006870-f5w6fw6q 4580 31 ketamine ketamine NNP cord-006870-f5w6fw6q 4580 32 . . . cord-006870-f5w6fw6q 4581 1 67 67 CD cord-006870-f5w6fw6q 4581 2 % % NN cord-006870-f5w6fw6q 4581 3 patients patient NNS cord-006870-f5w6fw6q 4581 4 had have VBD cord-006870-f5w6fw6q 4581 5 hospital hospital NN cord-006870-f5w6fw6q 4581 6 acquired acquire VBN cord-006870-f5w6fw6q 4581 7 infections infection NNS cord-006870-f5w6fw6q 4581 8 , , , cord-006870-f5w6fw6q 4581 9 34 34 CD cord-006870-f5w6fw6q 4581 10 % % NN cord-006870-f5w6fw6q 4581 11 patient patient NN cord-006870-f5w6fw6q 4581 12 had have VBD cord-006870-f5w6fw6q 4581 13 metabolic metabolic JJ cord-006870-f5w6fw6q 4581 14 acidosis acidosis NN cord-006870-f5w6fw6q 4581 15 , , , cord-006870-f5w6fw6q 4581 16 25 25 CD cord-006870-f5w6fw6q 4581 17 % % NN cord-006870-f5w6fw6q 4581 18 had have VBD cord-006870-f5w6fw6q 4581 19 ARDS ARDS NNP cord-006870-f5w6fw6q 4581 20 . . . cord-006870-f5w6fw6q 4582 1 This this DT cord-006870-f5w6fw6q 4582 2 is be VBZ cord-006870-f5w6fw6q 4582 3 one one CD cord-006870-f5w6fw6q 4582 4 of of IN cord-006870-f5w6fw6q 4582 5 the the DT cord-006870-f5w6fw6q 4582 6 largest large JJS cord-006870-f5w6fw6q 4582 7 single single JJ cord-006870-f5w6fw6q 4582 8 center center NN cord-006870-f5w6fw6q 4582 9 study study NN cord-006870-f5w6fw6q 4582 10 illustrating illustrate VBG cord-006870-f5w6fw6q 4582 11 the the DT cord-006870-f5w6fw6q 4582 12 efficacy efficacy NN cord-006870-f5w6fw6q 4582 13 of of IN cord-006870-f5w6fw6q 4582 14 ketamine ketamine NN cord-006870-f5w6fw6q 4582 15 in in IN cord-006870-f5w6fw6q 4582 16 aborting abort VBG cord-006870-f5w6fw6q 4582 17 RSE rse NN cord-006870-f5w6fw6q 4582 18 . . . cord-006870-f5w6fw6q 4583 1 Further further JJ cord-006870-f5w6fw6q 4583 2 study study NN cord-006870-f5w6fw6q 4583 3 should should MD cord-006870-f5w6fw6q 4583 4 address address VB cord-006870-f5w6fw6q 4583 5 the the DT cord-006870-f5w6fw6q 4583 6 difference difference NN cord-006870-f5w6fw6q 4583 7 in in IN cord-006870-f5w6fw6q 4583 8 incidence incidence NN cord-006870-f5w6fw6q 4583 9 of of IN cord-006870-f5w6fw6q 4583 10 complications complication NNS cord-006870-f5w6fw6q 4583 11 in in IN cord-006870-f5w6fw6q 4583 12 patients patient NNS cord-006870-f5w6fw6q 4583 13 with with IN cord-006870-f5w6fw6q 4583 14 usage usage NN cord-006870-f5w6fw6q 4583 15 of of IN cord-006870-f5w6fw6q 4583 16 ketamine ketamine NN cord-006870-f5w6fw6q 4583 17 versus versus IN cord-006870-f5w6fw6q 4583 18 groups group NNS cord-006870-f5w6fw6q 4583 19 alternative alternative JJ cord-006870-f5w6fw6q 4583 20 therapies therapy NNS cord-006870-f5w6fw6q 4583 21 . . . cord-006870-f5w6fw6q 4584 1 This this DT cord-006870-f5w6fw6q 4584 2 study study NN cord-006870-f5w6fw6q 4584 3 also also RB cord-006870-f5w6fw6q 4584 4 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 4584 5 the the DT cord-006870-f5w6fw6q 4584 6 etiology etiology NN cord-006870-f5w6fw6q 4584 7 of of IN cord-006870-f5w6fw6q 4584 8 seizures seizure NNS cord-006870-f5w6fw6q 4584 9 and and CC cord-006870-f5w6fw6q 4584 10 its -PRON- PRP$ cord-006870-f5w6fw6q 4584 11 influence influence NN cord-006870-f5w6fw6q 4584 12 on on IN cord-006870-f5w6fw6q 4584 13 efficacy efficacy NN cord-006870-f5w6fw6q 4584 14 of of IN cord-006870-f5w6fw6q 4584 15 ketamine ketamine NN cord-006870-f5w6fw6q 4584 16 in in IN cord-006870-f5w6fw6q 4584 17 aborting abort VBG cord-006870-f5w6fw6q 4584 18 RSE rse NN cord-006870-f5w6fw6q 4584 19 . . . cord-006870-f5w6fw6q 4585 1 Acute acute JJ cord-006870-f5w6fw6q 4585 2 cardiopulmonary cardiopulmonary JJ cord-006870-f5w6fw6q 4585 3 complications complication NNS cord-006870-f5w6fw6q 4585 4 are be VBP cord-006870-f5w6fw6q 4585 5 frequently frequently RB cord-006870-f5w6fw6q 4585 6 observed observe VBN cord-006870-f5w6fw6q 4585 7 in in IN cord-006870-f5w6fw6q 4585 8 convulsive convulsive JJ cord-006870-f5w6fw6q 4585 9 status status NN cord-006870-f5w6fw6q 4585 10 epilepticus epilepticus NN cord-006870-f5w6fw6q 4585 11 but but CC cord-006870-f5w6fw6q 4585 12 mechanism mechanism NN cord-006870-f5w6fw6q 4585 13 is be VBZ cord-006870-f5w6fw6q 4585 14 poorly poorly RB cord-006870-f5w6fw6q 4585 15 understood understand VBN cord-006870-f5w6fw6q 4585 16 . . . cord-006870-f5w6fw6q 4586 1 Complications complication NNS cord-006870-f5w6fw6q 4586 2 include include VBP cord-006870-f5w6fw6q 4586 3 tachy tachy NN cord-006870-f5w6fw6q 4586 4 - - HYPH cord-006870-f5w6fw6q 4586 5 arrhythmias arrhythmias RB cord-006870-f5w6fw6q 4586 6 , , , cord-006870-f5w6fw6q 4586 7 myocardial myocardial JJ cord-006870-f5w6fw6q 4586 8 ischemia ischemia NN cord-006870-f5w6fw6q 4586 9 , , , cord-006870-f5w6fw6q 4586 10 Takotsubo Takotsubo NNP cord-006870-f5w6fw6q 4586 11 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 4586 12 and and CC cord-006870-f5w6fw6q 4586 13 neurogenic neurogenic JJ cord-006870-f5w6fw6q 4586 14 pulmonary pulmonary JJ cord-006870-f5w6fw6q 4586 15 edema edema NN cord-006870-f5w6fw6q 4586 16 . . . cord-006870-f5w6fw6q 4587 1 Herein herein RB cord-006870-f5w6fw6q 4587 2 , , , cord-006870-f5w6fw6q 4587 3 we -PRON- PRP cord-006870-f5w6fw6q 4587 4 mapped map VBD cord-006870-f5w6fw6q 4587 5 evolution evolution NN cord-006870-f5w6fw6q 4587 6 of of IN cord-006870-f5w6fw6q 4587 7 cardiac cardiac JJ cord-006870-f5w6fw6q 4587 8 dysautonomia dysautonomia NN cord-006870-f5w6fw6q 4587 9 as as IN cord-006870-f5w6fw6q 4587 10 function function NN cord-006870-f5w6fw6q 4587 11 of of IN cord-006870-f5w6fw6q 4587 12 5 5 CD cord-006870-f5w6fw6q 4587 13 sequential sequential JJ cord-006870-f5w6fw6q 4587 14 electrographic electrographic JJ cord-006870-f5w6fw6q 4587 15 stages stage NNS cord-006870-f5w6fw6q 4587 16 of of IN cord-006870-f5w6fw6q 4587 17 SE SE NNP cord-006870-f5w6fw6q 4587 18 in in IN cord-006870-f5w6fw6q 4587 19 four four CD cord-006870-f5w6fw6q 4587 20 subjects subject NNS cord-006870-f5w6fw6q 4587 21 admitted admit VBN cord-006870-f5w6fw6q 4587 22 to to IN cord-006870-f5w6fw6q 4587 23 ICU ICU NNP cord-006870-f5w6fw6q 4587 24 . . . cord-006870-f5w6fw6q 4588 1 We -PRON- PRP cord-006870-f5w6fw6q 4588 2 hypothesize hypothesize VBP cord-006870-f5w6fw6q 4588 3 pathological pathological JJ cord-006870-f5w6fw6q 4588 4 co co NN cord-006870-f5w6fw6q 4588 5 - - NN cord-006870-f5w6fw6q 4588 6 activation activation NN cord-006870-f5w6fw6q 4588 7 of of IN cord-006870-f5w6fw6q 4588 8 both both DT cord-006870-f5w6fw6q 4588 9 arms arm NNS cord-006870-f5w6fw6q 4588 10 of of IN cord-006870-f5w6fw6q 4588 11 autonomic autonomic JJ cord-006870-f5w6fw6q 4588 12 system system NN cord-006870-f5w6fw6q 4588 13 contributes contribute VBZ cord-006870-f5w6fw6q 4588 14 to to IN cord-006870-f5w6fw6q 4588 15 cardiac cardiac JJ cord-006870-f5w6fw6q 4588 16 complications complication NNS cord-006870-f5w6fw6q 4588 17 . . . cord-006870-f5w6fw6q 4589 1 Heart heart NN cord-006870-f5w6fw6q 4589 2 rate rate NN cord-006870-f5w6fw6q 4589 3 variability variability NN cord-006870-f5w6fw6q 4589 4 ( ( -LRB- cord-006870-f5w6fw6q 4589 5 HRV HRV NNP cord-006870-f5w6fw6q 4589 6 ) ) -RRB- cord-006870-f5w6fw6q 4589 7 is be VBZ cord-006870-f5w6fw6q 4589 8 considered consider VBN cord-006870-f5w6fw6q 4589 9 a a DT cord-006870-f5w6fw6q 4589 10 proxy proxy NN cord-006870-f5w6fw6q 4589 11 for for IN cord-006870-f5w6fw6q 4589 12 ANS an NNS cord-006870-f5w6fw6q 4589 13 tone tone NN cord-006870-f5w6fw6q 4589 14 on on IN cord-006870-f5w6fw6q 4589 15 heart heart NN cord-006870-f5w6fw6q 4589 16 . . . cord-006870-f5w6fw6q 4590 1 We -PRON- PRP cord-006870-f5w6fw6q 4590 2 analyzed analyze VBD cord-006870-f5w6fw6q 4590 3 HRV HRV NNP cord-006870-f5w6fw6q 4590 4 in in IN cord-006870-f5w6fw6q 4590 5 time time NN cord-006870-f5w6fw6q 4590 6 and and CC cord-006870-f5w6fw6q 4590 7 frequency frequency NN cord-006870-f5w6fw6q 4590 8 domain domain NN cord-006870-f5w6fw6q 4590 9 , , , cord-006870-f5w6fw6q 4590 10 complexity complexity NN cord-006870-f5w6fw6q 4590 11 measure measure NN cord-006870-f5w6fw6q 4590 12 ( ( -LRB- cord-006870-f5w6fw6q 4590 13 Lempel Lempel NNP cord-006870-f5w6fw6q 4590 14 Ziv Ziv NNP cord-006870-f5w6fw6q 4590 15 - - HYPH cord-006870-f5w6fw6q 4590 16 LZ LZ NNP cord-006870-f5w6fw6q 4590 17 ) ) -RRB- cord-006870-f5w6fw6q 4590 18 during during IN cord-006870-f5w6fw6q 4590 19 SE SE NNP cord-006870-f5w6fw6q 4590 20 and and CC cord-006870-f5w6fw6q 4590 21 mapped map VBD cord-006870-f5w6fw6q 4590 22 changes change NNS cord-006870-f5w6fw6q 4590 23 as as IN cord-006870-f5w6fw6q 4590 24 function function NN cord-006870-f5w6fw6q 4590 25 of of IN cord-006870-f5w6fw6q 4590 26 stages stage NNS cord-006870-f5w6fw6q 4590 27 of of IN cord-006870-f5w6fw6q 4590 28 SE SE NNP cord-006870-f5w6fw6q 4590 29 as as IN cord-006870-f5w6fw6q 4590 30 determined determine VBN cord-006870-f5w6fw6q 4590 31 by by IN cord-006870-f5w6fw6q 4590 32 scalp scalp NN cord-006870-f5w6fw6q 4590 33 EEG EEG NNP cord-006870-f5w6fw6q 4590 34 . . . cord-006870-f5w6fw6q 4591 1 Conventional conventional JJ cord-006870-f5w6fw6q 4591 2 scalp scalp NN cord-006870-f5w6fw6q 4592 1 EEG EEG NNP cord-006870-f5w6fw6q 4592 2 recording recording NN cord-006870-f5w6fw6q 4592 3 and and CC cord-006870-f5w6fw6q 4592 4 lead lead VB cord-006870-f5w6fw6q 4592 5 I I NNP cord-006870-f5w6fw6q 4592 6 - - HYPH cord-006870-f5w6fw6q 4592 7 EKG EKG NNP cord-006870-f5w6fw6q 4593 1 ( ( -LRB- cord-006870-f5w6fw6q 4593 2 sampled sample VBN cord-006870-f5w6fw6q 4593 3 at at IN cord-006870-f5w6fw6q 4593 4 256 256 CD cord-006870-f5w6fw6q 4593 5 Hz Hz NNP cord-006870-f5w6fw6q 4593 6 ) ) -RRB- cord-006870-f5w6fw6q 4593 7 were be VBD cord-006870-f5w6fw6q 4593 8 analyzed analyze VBN cord-006870-f5w6fw6q 4593 9 using use VBG cord-006870-f5w6fw6q 4593 10 Kubios Kubios NNP cord-006870-f5w6fw6q 4593 11 HRV HRV NNP cord-006870-f5w6fw6q 4593 12 software software NN cord-006870-f5w6fw6q 4593 13 2.1 2.1 CD cord-006870-f5w6fw6q 4593 14 . . . cord-006870-f5w6fw6q 4594 1 Cardiac cardiac JJ cord-006870-f5w6fw6q 4594 2 vagal vagal JJ cord-006870-f5w6fw6q 4594 3 index index NN cord-006870-f5w6fw6q 4594 4 ( ( -LRB- cord-006870-f5w6fw6q 4594 5 CVI CVI NNP cord-006870-f5w6fw6q 4594 6 ) ) -RRB- cord-006870-f5w6fw6q 4594 7 and and CC cord-006870-f5w6fw6q 4594 8 cardiac cardiac JJ cord-006870-f5w6fw6q 4594 9 sympathetic sympathetic JJ cord-006870-f5w6fw6q 4594 10 index index NN cord-006870-f5w6fw6q 4594 11 ( ( -LRB- cord-006870-f5w6fw6q 4594 12 CSI CSI NNP cord-006870-f5w6fw6q 4594 13 ) ) -RRB- cord-006870-f5w6fw6q 4594 14 were be VBD cord-006870-f5w6fw6q 4594 15 calculated calculate VBN cord-006870-f5w6fw6q 4594 16 using use VBG cord-006870-f5w6fw6q 4594 17 geometric geometric JJ cord-006870-f5w6fw6q 4594 18 Lorenz Lorenz NNP cord-006870-f5w6fw6q 4594 19 - - HYPH cord-006870-f5w6fw6q 4594 20 plot plot NN cord-006870-f5w6fw6q 4594 21 method method NN cord-006870-f5w6fw6q 4594 22 . . . cord-006870-f5w6fw6q 4595 1 Parasympathetic parasympathetic JJ cord-006870-f5w6fw6q 4595 2 activity activity NN cord-006870-f5w6fw6q 4595 3 is be VBZ cord-006870-f5w6fw6q 4595 4 expressed express VBN cord-006870-f5w6fw6q 4595 5 in in IN cord-006870-f5w6fw6q 4595 6 RMSSD RMSSD NNP cord-006870-f5w6fw6q 4595 7 , , , cord-006870-f5w6fw6q 4595 8 pNN pNN NNP cord-006870-f5w6fw6q 4595 9 , , , cord-006870-f5w6fw6q 4595 10 CVI CVI NNP cord-006870-f5w6fw6q 4595 11 , , , cord-006870-f5w6fw6q 4595 12 and and CC cord-006870-f5w6fw6q 4595 13 HF HF NNP cord-006870-f5w6fw6q 4595 14 power power NN cord-006870-f5w6fw6q 4595 15 Four four CD cord-006870-f5w6fw6q 4595 16 adults adult NNS cord-006870-f5w6fw6q 4595 17 ( ( -LRB- cord-006870-f5w6fw6q 4595 18 range range VBP cord-006870-f5w6fw6q 4595 19 22 22 CD cord-006870-f5w6fw6q 4595 20 - - SYM cord-006870-f5w6fw6q 4595 21 59 59 CD cord-006870-f5w6fw6q 4595 22 ; ; : cord-006870-f5w6fw6q 4595 23 M=3 M=3 NNP cord-006870-f5w6fw6q 4595 24 ) ) -RRB- cord-006870-f5w6fw6q 4595 25 were be VBD cord-006870-f5w6fw6q 4595 26 admitted admit VBN cord-006870-f5w6fw6q 4595 27 to to IN cord-006870-f5w6fw6q 4595 28 ICU ICU NNP cord-006870-f5w6fw6q 4595 29 following follow VBG cord-006870-f5w6fw6q 4595 30 convulsive convulsive JJ cord-006870-f5w6fw6q 4595 31 SE se NN cord-006870-f5w6fw6q 4595 32 . . . cord-006870-f5w6fw6q 4596 1 Ictal Ictal NNP cord-006870-f5w6fw6q 4596 2 HRV HRV NNP cord-006870-f5w6fw6q 4596 3 changes change NNS cord-006870-f5w6fw6q 4596 4 initially initially RB cord-006870-f5w6fw6q 4596 5 reflected reflect VBD cord-006870-f5w6fw6q 4596 6 high high JJ cord-006870-f5w6fw6q 4596 7 sympathetic sympathetic JJ cord-006870-f5w6fw6q 4596 8 system system NN cord-006870-f5w6fw6q 4596 9 activation activation NN cord-006870-f5w6fw6q 4596 10 ( ( -LRB- cord-006870-f5w6fw6q 4596 11 high high JJ cord-006870-f5w6fw6q 4596 12 CSI CSI NNP cord-006870-f5w6fw6q 4596 13 ) ) -RRB- cord-006870-f5w6fw6q 4596 14 and and CC cord-006870-f5w6fw6q 4596 15 reduced reduce VBN cord-006870-f5w6fw6q 4596 16 vagal vagal JJ cord-006870-f5w6fw6q 4596 17 tone tone NN cord-006870-f5w6fw6q 4596 18 ( ( -LRB- cord-006870-f5w6fw6q 4596 19 low low JJ cord-006870-f5w6fw6q 4596 20 HF HF NNP cord-006870-f5w6fw6q 4596 21 , , , cord-006870-f5w6fw6q 4596 22 RMSSD RMSSD NNP cord-006870-f5w6fw6q 4596 23 ) ) -RRB- cord-006870-f5w6fw6q 4596 24 as as IN cord-006870-f5w6fw6q 4596 25 reported report VBN cord-006870-f5w6fw6q 4596 26 previously previously RB cord-006870-f5w6fw6q 4596 27 with with IN cord-006870-f5w6fw6q 4596 28 convulsive convulsive JJ cord-006870-f5w6fw6q 4596 29 seizure seizure NN cord-006870-f5w6fw6q 4596 30 . . . cord-006870-f5w6fw6q 4597 1 Earlier early JJR cord-006870-f5w6fw6q 4597 2 stages stage NNS cord-006870-f5w6fw6q 4597 3 of of IN cord-006870-f5w6fw6q 4597 4 SE SE NNP cord-006870-f5w6fw6q 4597 5 ( ( -LRB- cord-006870-f5w6fw6q 4597 6 Stage stage NN cord-006870-f5w6fw6q 4597 7 I I NNP cord-006870-f5w6fw6q 4597 8 and and CC cord-006870-f5w6fw6q 4597 9 II II NNP cord-006870-f5w6fw6q 4597 10 ) ) -RRB- cord-006870-f5w6fw6q 4597 11 were be VBD cord-006870-f5w6fw6q 4597 12 marked mark VBN cord-006870-f5w6fw6q 4597 13 by by IN cord-006870-f5w6fw6q 4597 14 dual dual JJ cord-006870-f5w6fw6q 4597 15 activation activation NN cord-006870-f5w6fw6q 4597 16 of of IN cord-006870-f5w6fw6q 4597 17 the the DT cord-006870-f5w6fw6q 4597 18 ANS an NNS cord-006870-f5w6fw6q 4597 19 with with IN cord-006870-f5w6fw6q 4597 20 sympathetic sympathetic JJ cord-006870-f5w6fw6q 4597 21 predominance predominance NN cord-006870-f5w6fw6q 4597 22 ( ( -LRB- cord-006870-f5w6fw6q 4597 23 lower low JJR cord-006870-f5w6fw6q 4597 24 CVI CVI NNP cord-006870-f5w6fw6q 4597 25 / / SYM cord-006870-f5w6fw6q 4597 26 CSI CSI NNP cord-006870-f5w6fw6q 4597 27 ratio ratio NN cord-006870-f5w6fw6q 4597 28 ) ) -RRB- cord-006870-f5w6fw6q 4597 29 . . . cord-006870-f5w6fw6q 4598 1 Later later JJ cord-006870-f5w6fw6q 4598 2 stages stage NNS cord-006870-f5w6fw6q 4598 3 of of IN cord-006870-f5w6fw6q 4598 4 SE SE NNP cord-006870-f5w6fw6q 4598 5 ( ( -LRB- cord-006870-f5w6fw6q 4598 6 Stage Stage NNP cord-006870-f5w6fw6q 4598 7 IV IV NNP cord-006870-f5w6fw6q 4598 8 and and CC cord-006870-f5w6fw6q 4598 9 V V NNP cord-006870-f5w6fw6q 4598 10 ) ) -RRB- cord-006870-f5w6fw6q 4598 11 , , , cord-006870-f5w6fw6q 4598 12 demonstrated demonstrate VBD cord-006870-f5w6fw6q 4598 13 progressive progressive JJ cord-006870-f5w6fw6q 4598 14 increase increase NN cord-006870-f5w6fw6q 4598 15 in in IN cord-006870-f5w6fw6q 4598 16 parasympathetic parasympathetic JJ cord-006870-f5w6fw6q 4598 17 activity activity NN cord-006870-f5w6fw6q 4598 18 ( ( -LRB- cord-006870-f5w6fw6q 4598 19 HF HF NNP cord-006870-f5w6fw6q 4598 20 power power NN cord-006870-f5w6fw6q 4598 21 , , , cord-006870-f5w6fw6q 4598 22 RMSSD RMSSD NNP cord-006870-f5w6fw6q 4598 23 , , , cord-006870-f5w6fw6q 4598 24 CVI CVI NNP cord-006870-f5w6fw6q 4598 25 , , , cord-006870-f5w6fw6q 4598 26 CVI CVI NNP cord-006870-f5w6fw6q 4598 27 / / SYM cord-006870-f5w6fw6q 4598 28 CSI CSI NNP cord-006870-f5w6fw6q 4598 29 ratio ratio NN cord-006870-f5w6fw6q 4598 30 ) ) -RRB- cord-006870-f5w6fw6q 4598 31 . . . cord-006870-f5w6fw6q 4599 1 HF HF NNP cord-006870-f5w6fw6q 4599 2 power power NN cord-006870-f5w6fw6q 4599 3 and and CC cord-006870-f5w6fw6q 4599 4 RMSSD RMSSD NNP cord-006870-f5w6fw6q 4599 5 at at IN cord-006870-f5w6fw6q 4599 6 Stage Stage NNP cord-006870-f5w6fw6q 4599 7 V V NNP cord-006870-f5w6fw6q 4599 8 SE SE NNP cord-006870-f5w6fw6q 4599 9 was be VBD cord-006870-f5w6fw6q 4599 10 three three CD cord-006870-f5w6fw6q 4599 11 times time NNS cord-006870-f5w6fw6q 4599 12 higher high JJR cord-006870-f5w6fw6q 4599 13 than than IN cord-006870-f5w6fw6q 4599 14 during during IN cord-006870-f5w6fw6q 4599 15 discrete discrete JJ cord-006870-f5w6fw6q 4599 16 seizure seizure NN cord-006870-f5w6fw6q 4599 17 . . . cord-006870-f5w6fw6q 4600 1 LZ LZ NNP cord-006870-f5w6fw6q 4600 2 complexity complexity NN cord-006870-f5w6fw6q 4600 3 measure measure NN cord-006870-f5w6fw6q 4600 4 downtrended downtrende VBN cord-006870-f5w6fw6q 4600 5 with with IN cord-006870-f5w6fw6q 4600 6 the the DT cord-006870-f5w6fw6q 4600 7 loss loss NN cord-006870-f5w6fw6q 4600 8 of of IN cord-006870-f5w6fw6q 4600 9 fluctuations fluctuation NNS cord-006870-f5w6fw6q 4600 10 in in IN cord-006870-f5w6fw6q 4600 11 late late JJ cord-006870-f5w6fw6q 4600 12 stages stage NNS cord-006870-f5w6fw6q 4600 13 of of IN cord-006870-f5w6fw6q 4600 14 SE SE NNP cord-006870-f5w6fw6q 4600 15 . . . cord-006870-f5w6fw6q 4601 1 In in IN cord-006870-f5w6fw6q 4601 2 one one CD cord-006870-f5w6fw6q 4601 3 subject subject NN cord-006870-f5w6fw6q 4601 4 SE se NN cord-006870-f5w6fw6q 4601 5 terminated terminate VBD cord-006870-f5w6fw6q 4601 6 with with IN cord-006870-f5w6fw6q 4601 7 asystole asystole NN cord-006870-f5w6fw6q 4602 1 This this DT cord-006870-f5w6fw6q 4602 2 case case NN cord-006870-f5w6fw6q 4602 3 series series NN cord-006870-f5w6fw6q 4602 4 highlights highlight VBZ cord-006870-f5w6fw6q 4602 5 dynamic dynamic JJ cord-006870-f5w6fw6q 4602 6 changes change NNS cord-006870-f5w6fw6q 4602 7 in in IN cord-006870-f5w6fw6q 4602 8 sympatho sympatho JJ cord-006870-f5w6fw6q 4602 9 - - HYPH cord-006870-f5w6fw6q 4602 10 vagal vagal JJ cord-006870-f5w6fw6q 4602 11 imbalances imbalance NNS cord-006870-f5w6fw6q 4602 12 with with IN cord-006870-f5w6fw6q 4602 13 progressive progressive JJ cord-006870-f5w6fw6q 4602 14 SE SE NNP cord-006870-f5w6fw6q 4602 15 . . . cord-006870-f5w6fw6q 4603 1 Dual dual JJ cord-006870-f5w6fw6q 4603 2 activation activation NN cord-006870-f5w6fw6q 4603 3 of of IN cord-006870-f5w6fw6q 4603 4 sympatho sympatho JJ cord-006870-f5w6fw6q 4603 5 - - HYPH cord-006870-f5w6fw6q 4603 6 parasympathetic parasympathetic JJ cord-006870-f5w6fw6q 4603 7 system system NN cord-006870-f5w6fw6q 4603 8 and and CC cord-006870-f5w6fw6q 4603 9 loss loss NN cord-006870-f5w6fw6q 4603 10 of of IN cord-006870-f5w6fw6q 4603 11 complexity complexity NN cord-006870-f5w6fw6q 4603 12 measures measure NNS cord-006870-f5w6fw6q 4603 13 are be VBP cord-006870-f5w6fw6q 4603 14 associated associate VBN cord-006870-f5w6fw6q 4603 15 with with IN cord-006870-f5w6fw6q 4603 16 increased increase VBN cord-006870-f5w6fw6q 4603 17 cardiac cardiac JJ cord-006870-f5w6fw6q 4603 18 complications complication NNS cord-006870-f5w6fw6q 4603 19 . . . cord-006870-f5w6fw6q 4604 1 Therapies therapy NNS cord-006870-f5w6fw6q 4604 2 directed direct VBN cord-006870-f5w6fw6q 4604 3 towards towards IN cord-006870-f5w6fw6q 4604 4 stabilization stabilization NN cord-006870-f5w6fw6q 4604 5 of of IN cord-006870-f5w6fw6q 4604 6 cardiac cardiac JJ cord-006870-f5w6fw6q 4604 7 dysautonomia dysautonomia NN cord-006870-f5w6fw6q 4604 8 might may MD cord-006870-f5w6fw6q 4604 9 minimize minimize VB cord-006870-f5w6fw6q 4604 10 complications complication NNS cord-006870-f5w6fw6q 4604 11 Super super JJ cord-006870-f5w6fw6q 4604 12 - - JJ cord-006870-f5w6fw6q 4604 13 refractory refractory JJ cord-006870-f5w6fw6q 4604 14 status status NN cord-006870-f5w6fw6q 4604 15 epilepticus epilepticus NN cord-006870-f5w6fw6q 4604 16 ( ( -LRB- cord-006870-f5w6fw6q 4604 17 SRSE SRSE NNP cord-006870-f5w6fw6q 4604 18 ) ) -RRB- cord-006870-f5w6fw6q 4604 19 is be VBZ cord-006870-f5w6fw6q 4604 20 a a DT cord-006870-f5w6fw6q 4604 21 life life NN cord-006870-f5w6fw6q 4604 22 - - HYPH cord-006870-f5w6fw6q 4604 23 threatening threaten VBG cord-006870-f5w6fw6q 4604 24 neurological neurological JJ cord-006870-f5w6fw6q 4604 25 condition condition NN cord-006870-f5w6fw6q 4604 26 that that WDT cord-006870-f5w6fw6q 4604 27 is be VBZ cord-006870-f5w6fw6q 4604 28 characterized characterize VBN cord-006870-f5w6fw6q 4604 29 by by IN cord-006870-f5w6fw6q 4604 30 status status NN cord-006870-f5w6fw6q 4604 31 epilepticus epilepticus NN cord-006870-f5w6fw6q 4604 32 that that WDT cord-006870-f5w6fw6q 4604 33 persists persist VBZ cord-006870-f5w6fw6q 4604 34 for for IN cord-006870-f5w6fw6q 4604 35 24 24 CD cord-006870-f5w6fw6q 4604 36 hours hour NNS cord-006870-f5w6fw6q 4604 37 despite despite IN cord-006870-f5w6fw6q 4604 38 treatment treatment NN cord-006870-f5w6fw6q 4604 39 with with IN cord-006870-f5w6fw6q 4604 40 first- first- NN cord-006870-f5w6fw6q 4604 41 , , , cord-006870-f5w6fw6q 4604 42 second- second- JJ cord-006870-f5w6fw6q 4604 43 , , , cord-006870-f5w6fw6q 4604 44 and and CC cord-006870-f5w6fw6q 4604 45 third third JJ cord-006870-f5w6fw6q 4604 46 - - HYPH cord-006870-f5w6fw6q 4604 47 line line NN cord-006870-f5w6fw6q 4604 48 agents agent NNS cord-006870-f5w6fw6q 4604 49 ( ( -LRB- cord-006870-f5w6fw6q 4604 50 TLAs TLAs NNP cord-006870-f5w6fw6q 4604 51 ) ) -RRB- cord-006870-f5w6fw6q 4604 52 or or CC cord-006870-f5w6fw6q 4604 53 upon upon IN cord-006870-f5w6fw6q 4604 54 the the DT cord-006870-f5w6fw6q 4604 55 weaning weaning NN cord-006870-f5w6fw6q 4604 56 of of IN cord-006870-f5w6fw6q 4604 57 TLAs tla NNS cord-006870-f5w6fw6q 4604 58 . . . cord-006870-f5w6fw6q 4605 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4605 2 is be VBZ cord-006870-f5w6fw6q 4605 3 associated associate VBN cord-006870-f5w6fw6q 4605 4 with with IN cord-006870-f5w6fw6q 4605 5 limited limited JJ cord-006870-f5w6fw6q 4605 6 treatment treatment NN cord-006870-f5w6fw6q 4605 7 options option NNS cord-006870-f5w6fw6q 4605 8 , , , cord-006870-f5w6fw6q 4605 9 and and CC cord-006870-f5w6fw6q 4605 10 high high JJ cord-006870-f5w6fw6q 4605 11 morbidity morbidity NN cord-006870-f5w6fw6q 4605 12 and and CC cord-006870-f5w6fw6q 4605 13 mortality mortality NN cord-006870-f5w6fw6q 4605 14 . . . cord-006870-f5w6fw6q 4606 1 This this DT cord-006870-f5w6fw6q 4606 2 study study NN cord-006870-f5w6fw6q 4606 3 aims aim VBZ cord-006870-f5w6fw6q 4606 4 to to TO cord-006870-f5w6fw6q 4606 5 describe describe VB cord-006870-f5w6fw6q 4606 6 and and CC cord-006870-f5w6fw6q 4606 7 quantify quantify VB cord-006870-f5w6fw6q 4606 8 inpatient inpatient JJ cord-006870-f5w6fw6q 4606 9 SRSE SRSE NNP cord-006870-f5w6fw6q 4606 10 treatment treatment NN cord-006870-f5w6fw6q 4606 11 and and CC cord-006870-f5w6fw6q 4606 12 its -PRON- PRP$ cord-006870-f5w6fw6q 4606 13 associated associate VBN cord-006870-f5w6fw6q 4606 14 outcomes outcome NNS cord-006870-f5w6fw6q 4606 15 in in IN cord-006870-f5w6fw6q 4606 16 the the DT cord-006870-f5w6fw6q 4606 17 US US NNP cord-006870-f5w6fw6q 4606 18 . . . cord-006870-f5w6fw6q 4607 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4607 2 cases case NNS cord-006870-f5w6fw6q 4607 3 were be VBD cord-006870-f5w6fw6q 4607 4 classified classify VBN cord-006870-f5w6fw6q 4607 5 retrospectively retrospectively RB cord-006870-f5w6fw6q 4607 6 using use VBG cord-006870-f5w6fw6q 4607 7 a a DT cord-006870-f5w6fw6q 4607 8 modified modify VBN cord-006870-f5w6fw6q 4607 9 version version NN cord-006870-f5w6fw6q 4607 10 of of IN cord-006870-f5w6fw6q 4607 11 a a DT cord-006870-f5w6fw6q 4607 12 previously previously RB cord-006870-f5w6fw6q 4607 13 published publish VBN cord-006870-f5w6fw6q 4607 14 algorithm algorithm NN cord-006870-f5w6fw6q 4607 15 applied apply VBD cord-006870-f5w6fw6q 4607 16 to to IN cord-006870-f5w6fw6q 4607 17 a a DT cord-006870-f5w6fw6q 4607 18 large large JJ cord-006870-f5w6fw6q 4607 19 , , , cord-006870-f5w6fw6q 4607 20 de de NN cord-006870-f5w6fw6q 4607 21 - - VBN cord-006870-f5w6fw6q 4607 22 identified identify VBN cord-006870-f5w6fw6q 4607 23 , , , cord-006870-f5w6fw6q 4607 24 US US NNP cord-006870-f5w6fw6q 4607 25 electronic electronic JJ cord-006870-f5w6fw6q 4607 26 health health NN cord-006870-f5w6fw6q 4607 27 record record NN cord-006870-f5w6fw6q 4607 28 database database NN cord-006870-f5w6fw6q 4607 29 ( ( -LRB- cord-006870-f5w6fw6q 4607 30 Cerner Cerner NNP cord-006870-f5w6fw6q 4607 31 Health Health NNP cord-006870-f5w6fw6q 4607 32 Facts fact NNS cord-006870-f5w6fw6q 4608 1 ® ® LS cord-006870-f5w6fw6q 4608 2 ) ) -RRB- cord-006870-f5w6fw6q 4608 3 covering cover VBG cord-006870-f5w6fw6q 4609 1 > > XX cord-006870-f5w6fw6q 4609 2 600 600 CD cord-006870-f5w6fw6q 4609 3 hospitals hospital NNS cord-006870-f5w6fw6q 4609 4 ( ( -LRB- cord-006870-f5w6fw6q 4609 5 2000 2000 CD cord-006870-f5w6fw6q 4609 6 ) ) -RRB- cord-006870-f5w6fw6q 4609 7 ( ( -LRB- cord-006870-f5w6fw6q 4609 8 2001 2001 CD cord-006870-f5w6fw6q 4609 9 ) ) -RRB- cord-006870-f5w6fw6q 4609 10 ( ( -LRB- cord-006870-f5w6fw6q 4609 11 2002 2002 CD cord-006870-f5w6fw6q 4609 12 ) ) -RRB- cord-006870-f5w6fw6q 4609 13 ( ( -LRB- cord-006870-f5w6fw6q 4609 14 2003 2003 CD cord-006870-f5w6fw6q 4609 15 ) ) -RRB- cord-006870-f5w6fw6q 4609 16 ( ( -LRB- cord-006870-f5w6fw6q 4609 17 2004 2004 CD cord-006870-f5w6fw6q 4609 18 ) ) -RRB- cord-006870-f5w6fw6q 4609 19 ( ( -LRB- cord-006870-f5w6fw6q 4609 20 2005 2005 CD cord-006870-f5w6fw6q 4609 21 ) ) -RRB- cord-006870-f5w6fw6q 4609 22 ( ( -LRB- cord-006870-f5w6fw6q 4609 23 2006 2006 CD cord-006870-f5w6fw6q 4609 24 ) ) -RRB- cord-006870-f5w6fw6q 4609 25 ( ( -LRB- cord-006870-f5w6fw6q 4609 26 2007 2007 CD cord-006870-f5w6fw6q 4609 27 ) ) -RRB- cord-006870-f5w6fw6q 4609 28 ( ( -LRB- cord-006870-f5w6fw6q 4609 29 2008 2008 CD cord-006870-f5w6fw6q 4609 30 ) ) -RRB- cord-006870-f5w6fw6q 4609 31 ( ( -LRB- cord-006870-f5w6fw6q 4609 32 2009 2009 CD cord-006870-f5w6fw6q 4609 33 ) ) -RRB- cord-006870-f5w6fw6q 4610 1 ( ( -LRB- cord-006870-f5w6fw6q 4610 2 2010 2010 CD cord-006870-f5w6fw6q 4610 3 ) ) -RRB- cord-006870-f5w6fw6q 4611 1 ( ( -LRB- cord-006870-f5w6fw6q 4611 2 2011 2011 CD cord-006870-f5w6fw6q 4611 3 ) ) -RRB- cord-006870-f5w6fw6q 4612 1 ( ( -LRB- cord-006870-f5w6fw6q 4612 2 2012 2012 CD cord-006870-f5w6fw6q 4612 3 ) ) -RRB- cord-006870-f5w6fw6q 4613 1 ( ( -LRB- cord-006870-f5w6fw6q 4613 2 2013 2013 CD cord-006870-f5w6fw6q 4613 3 ) ) -RRB- cord-006870-f5w6fw6q 4614 1 ( ( -LRB- cord-006870-f5w6fw6q 4614 2 2014 2014 CD cord-006870-f5w6fw6q 4614 3 ) ) -RRB- cord-006870-f5w6fw6q 4614 4 ( ( -LRB- cord-006870-f5w6fw6q 4614 5 2015 2015 CD cord-006870-f5w6fw6q 4614 6 ) ) -RRB- cord-006870-f5w6fw6q 4614 7 . . . cord-006870-f5w6fw6q 4615 1 Cases case NNS cord-006870-f5w6fw6q 4615 2 were be VBD cord-006870-f5w6fw6q 4615 3 classified classify VBN cord-006870-f5w6fw6q 4615 4 utilizing utilize VBG cord-006870-f5w6fw6q 4615 5 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 4615 6 and and CC cord-006870-f5w6fw6q 4615 7 procedure procedure NN cord-006870-f5w6fw6q 4615 8 coding coding NN cord-006870-f5w6fw6q 4615 9 for for IN cord-006870-f5w6fw6q 4615 10 status status NN cord-006870-f5w6fw6q 4615 11 epilepticus epilepticus NN cord-006870-f5w6fw6q 4615 12 ( ( -LRB- cord-006870-f5w6fw6q 4615 13 345.00 345.00 CD cord-006870-f5w6fw6q 4615 14 , , , cord-006870-f5w6fw6q 4615 15 345.01 345.01 CD cord-006870-f5w6fw6q 4615 16 , , , cord-006870-f5w6fw6q 4615 17 345.1x 345.1x CD cord-006870-f5w6fw6q 4615 18 , , , cord-006870-f5w6fw6q 4615 19 345.3 345.3 CD cord-006870-f5w6fw6q 4615 20 , , , cord-006870-f5w6fw6q 4615 21 345.41 345.41 CD cord-006870-f5w6fw6q 4615 22 , , , cord-006870-f5w6fw6q 4615 23 345.51 345.51 CD cord-006870-f5w6fw6q 4615 24 and and CC cord-006870-f5w6fw6q 4615 25 345.81 345.81 CD cord-006870-f5w6fw6q 4615 26 ) ) -RRB- cord-006870-f5w6fw6q 4615 27 , , , cord-006870-f5w6fw6q 4615 28 ventilator ventilator NN cord-006870-f5w6fw6q 4615 29 support support NN cord-006870-f5w6fw6q 4615 30 or or CC cord-006870-f5w6fw6q 4615 31 with with IN cord-006870-f5w6fw6q 4615 32 LOS>180 los>180 JJ cord-006870-f5w6fw6q 4615 33 days day NNS cord-006870-f5w6fw6q 4615 34 or or CC cord-006870-f5w6fw6q 4615 35 missing miss VBG cord-006870-f5w6fw6q 4615 36 age age NN cord-006870-f5w6fw6q 4615 37 were be VBD cord-006870-f5w6fw6q 4615 38 excluded exclude VBN cord-006870-f5w6fw6q 4615 39 . . . cord-006870-f5w6fw6q 4616 1 Univariate Univariate NNP cord-006870-f5w6fw6q 4616 2 statistics statistic NNS cord-006870-f5w6fw6q 4616 3 were be VBD cord-006870-f5w6fw6q 4616 4 used use VBN cord-006870-f5w6fw6q 4616 5 to to TO cord-006870-f5w6fw6q 4616 6 describe describe VB cord-006870-f5w6fw6q 4616 7 mortality mortality NN cord-006870-f5w6fw6q 4616 8 , , , cord-006870-f5w6fw6q 4616 9 hospital hospital NN cord-006870-f5w6fw6q 4616 10 LOS LOS NNP cord-006870-f5w6fw6q 4616 11 , , , cord-006870-f5w6fw6q 4616 12 ICU ICU NNP cord-006870-f5w6fw6q 4616 13 LOS LOS NNP cord-006870-f5w6fw6q 4616 14 , , , cord-006870-f5w6fw6q 4616 15 and and CC cord-006870-f5w6fw6q 4616 16 discharge discharge NN cord-006870-f5w6fw6q 4616 17 disposition disposition NN cord-006870-f5w6fw6q 4616 18 . . . cord-006870-f5w6fw6q 4617 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4617 2 algorithm algorithm NN cord-006870-f5w6fw6q 4617 3 classified classify VBD cord-006870-f5w6fw6q 4617 4 1153 1153 CD cord-006870-f5w6fw6q 4617 5 cases case NNS cord-006870-f5w6fw6q 4617 6 as as IN cord-006870-f5w6fw6q 4617 7 SRSE SRSE NNP cord-006870-f5w6fw6q 4617 8 ( ( -LRB- cord-006870-f5w6fw6q 4617 9 1137 1137 CD cord-006870-f5w6fw6q 4617 10 patients patient NNS cord-006870-f5w6fw6q 4617 11 ) ) -RRB- cord-006870-f5w6fw6q 4617 12 . . . cord-006870-f5w6fw6q 4618 1 Most Most JJS cord-006870-f5w6fw6q 4618 2 cases case NNS cord-006870-f5w6fw6q 4618 3 ( ( -LRB- cord-006870-f5w6fw6q 4618 4 61 61 CD cord-006870-f5w6fw6q 4618 5 % % NN cord-006870-f5w6fw6q 4618 6 ) ) -RRB- cord-006870-f5w6fw6q 4618 7 were be VBD cord-006870-f5w6fw6q 4618 8 to to IN cord-006870-f5w6fw6q 4618 9 large large JJ cord-006870-f5w6fw6q 4618 10 ( ( -LRB- cord-006870-f5w6fw6q 4618 11 300 300 CD cord-006870-f5w6fw6q 4618 12 + + SYM cord-006870-f5w6fw6q 4618 13 beds bed NNS cord-006870-f5w6fw6q 4618 14 ) ) -RRB- cord-006870-f5w6fw6q 4618 15 and/or and/or CC cord-006870-f5w6fw6q 4618 16 teaching teach VBG cord-006870-f5w6fw6q 4618 17 hospitals hospital NNS cord-006870-f5w6fw6q 4618 18 ( ( -LRB- cord-006870-f5w6fw6q 4618 19 86 86 CD cord-006870-f5w6fw6q 4618 20 % % NN cord-006870-f5w6fw6q 4618 21 ) ) -RRB- cord-006870-f5w6fw6q 4618 22 . . . cord-006870-f5w6fw6q 4619 1 Mean mean JJ cord-006870-f5w6fw6q 4619 2 hospital hospital NN cord-006870-f5w6fw6q 4619 3 LOS LOS NNP cord-006870-f5w6fw6q 4619 4 was be VBD cord-006870-f5w6fw6q 4619 5 24.4 24.4 CD cord-006870-f5w6fw6q 4619 6 days day NNS cord-006870-f5w6fw6q 4619 7 , , , cord-006870-f5w6fw6q 4619 8 and and CC cord-006870-f5w6fw6q 4619 9 ICU ICU NNP cord-006870-f5w6fw6q 4619 10 LOS LOS NNP cord-006870-f5w6fw6q 4619 11 was be VBD cord-006870-f5w6fw6q 4619 12 15.1 15.1 CD cord-006870-f5w6fw6q 4619 13 days day NNS cord-006870-f5w6fw6q 4619 14 . . . cord-006870-f5w6fw6q 4620 1 Both both DT cord-006870-f5w6fw6q 4620 2 LOS LOS NNP cord-006870-f5w6fw6q 4620 3 and and CC cord-006870-f5w6fw6q 4620 4 ICU ICU NNP cord-006870-f5w6fw6q 4620 5 LOS LOS NNP cord-006870-f5w6fw6q 4620 6 were be VBD cord-006870-f5w6fw6q 4620 7 significa significa JJ cord-006870-f5w6fw6q 4620 8 Average average JJ cord-006870-f5w6fw6q 4620 9 mortality mortality NN cord-006870-f5w6fw6q 4620 10 rate rate NN cord-006870-f5w6fw6q 4620 11 was be VBD cord-006870-f5w6fw6q 4620 12 23.5 23.5 CD cord-006870-f5w6fw6q 4620 13 % % NN cord-006870-f5w6fw6q 4620 14 . . . cord-006870-f5w6fw6q 4621 1 Mortality mortality NN cord-006870-f5w6fw6q 4621 2 rates rate NNS cord-006870-f5w6fw6q 4621 3 increased increase VBD cord-006870-f5w6fw6q 4621 4 with with IN cord-006870-f5w6fw6q 4621 5 number number NN cord-006870-f5w6fw6q 4621 6 of of IN cord-006870-f5w6fw6q 4621 7 TLAs tla NNS cord-006870-f5w6fw6q 4621 8 used use VBN cord-006870-f5w6fw6q 4621 9 ( ( -LRB- cord-006870-f5w6fw6q 4621 10 1 1 CD cord-006870-f5w6fw6q 4621 11 - - SYM cord-006870-f5w6fw6q 4621 12 2 2 CD cord-006870-f5w6fw6q 4621 13 TLA=21.5 tla=21.5 CD cord-006870-f5w6fw6q 4621 14 % % NN cord-006870-f5w6fw6q 4621 15 ; ; : cord-006870-f5w6fw6q 4621 16 3-rged 3-rged CD cord-006870-f5w6fw6q 4621 17 home home NN cord-006870-f5w6fw6q 4621 18 ( ( -LRB- cord-006870-f5w6fw6q 4621 19 6 6 CD cord-006870-f5w6fw6q 4621 20 % % NN cord-006870-f5w6fw6q 4621 21 with with IN cord-006870-f5w6fw6q 4621 22 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 4621 23 ) ) -RRB- cord-006870-f5w6fw6q 4621 24 , , , cord-006870-f5w6fw6q 4621 25 while while IN cord-006870-f5w6fw6q 4621 26 32 32 CD cord-006870-f5w6fw6q 4621 27 % % NN cord-006870-f5w6fw6q 4621 28 ( ( -LRB- cord-006870-f5w6fw6q 4621 29 N=285 N=285 NNP cord-006870-f5w6fw6q 4621 30 ) ) -RRB- cord-006870-f5w6fw6q 4621 31 were be VBD cord-006870-f5w6fw6q 4621 32 discharged discharge VBN cord-006870-f5w6fw6q 4621 33 to to IN cord-006870-f5w6fw6q 4621 34 another another DT cord-006870-f5w6fw6q 4621 35 facility facility NN cord-006870-f5w6fw6q 4621 36 . . . cord-006870-f5w6fw6q 4622 1 Treatment treatment NN cord-006870-f5w6fw6q 4622 2 of of IN cord-006870-f5w6fw6q 4622 3 SRSE SRSE NNP cord-006870-f5w6fw6q 4622 4 requires require VBZ cord-006870-f5w6fw6q 4622 5 acute acute JJ cord-006870-f5w6fw6q 4622 6 , , , cord-006870-f5w6fw6q 4622 7 intensive intensive JJ cord-006870-f5w6fw6q 4622 8 management management NN cord-006870-f5w6fw6q 4622 9 in in IN cord-006870-f5w6fw6q 4622 10 the the DT cord-006870-f5w6fw6q 4622 11 hospital hospital NN cord-006870-f5w6fw6q 4622 12 setting setting NN cord-006870-f5w6fw6q 4622 13 . . . cord-006870-f5w6fw6q 4623 1 LOS LOS NNP cord-006870-f5w6fw6q 4623 2 and and CC cord-006870-f5w6fw6q 4623 3 mortality mortality NN cord-006870-f5w6fw6q 4623 4 rates rate NNS cord-006870-f5w6fw6q 4623 5 were be VBD cord-006870-f5w6fw6q 4623 6 high high JJ cord-006870-f5w6fw6q 4623 7 and and CC cord-006870-f5w6fw6q 4623 8 increased increase VBD cord-006870-f5w6fw6q 4623 9 with with IN cord-006870-f5w6fw6q 4623 10 increasing increase VBG cord-006870-f5w6fw6q 4623 11 use use NN cord-006870-f5w6fw6q 4623 12 of of IN cord-006870-f5w6fw6q 4623 13 TLAs tla NNS cord-006870-f5w6fw6q 4623 14 . . . cord-006870-f5w6fw6q 4624 1 While while IN cord-006870-f5w6fw6q 4624 2 good good JJ cord-006870-f5w6fw6q 4624 3 outcomes outcome NNS cord-006870-f5w6fw6q 4624 4 remain remain VBP cord-006870-f5w6fw6q 4624 5 possible possible JJ cord-006870-f5w6fw6q 4624 6 even even RB cord-006870-f5w6fw6q 4624 7 after after IN cord-006870-f5w6fw6q 4624 8 SRSE SRSE NNP cord-006870-f5w6fw6q 4624 9 , , , cord-006870-f5w6fw6q 4624 10 additional additional JJ cord-006870-f5w6fw6q 4624 11 interventions intervention NNS cord-006870-f5w6fw6q 4624 12 are be VBP cord-006870-f5w6fw6q 4624 13 needed need VBN cord-006870-f5w6fw6q 4624 14 that that WDT cord-006870-f5w6fw6q 4624 15 enable enable VB cord-006870-f5w6fw6q 4624 16 seizure seizure NN cord-006870-f5w6fw6q 4624 17 control control NN cord-006870-f5w6fw6q 4624 18 , , , cord-006870-f5w6fw6q 4624 19 liberation liberation NN cord-006870-f5w6fw6q 4624 20 from from IN cord-006870-f5w6fw6q 4624 21 anesthetic anesthetic NN cord-006870-f5w6fw6q 4624 22 and and CC cord-006870-f5w6fw6q 4624 23 ventilator ventilator NN cord-006870-f5w6fw6q 4624 24 management management NN cord-006870-f5w6fw6q 4624 25 , , , cord-006870-f5w6fw6q 4624 26 and and CC cord-006870-f5w6fw6q 4624 27 improved improve VBN cord-006870-f5w6fw6q 4624 28 mortality mortality NN cord-006870-f5w6fw6q 4624 29 . . . cord-006870-f5w6fw6q 4625 1 Refractory refractory JJ cord-006870-f5w6fw6q 4625 2 status status NN cord-006870-f5w6fw6q 4625 3 epilepticus epilepticus NN cord-006870-f5w6fw6q 4625 4 ( ( -LRB- cord-006870-f5w6fw6q 4625 5 SE SE NNP cord-006870-f5w6fw6q 4625 6 ) ) -RRB- cord-006870-f5w6fw6q 4625 7 carries carry VBZ cord-006870-f5w6fw6q 4625 8 an an DT cord-006870-f5w6fw6q 4625 9 exceedingly exceedingly RB cord-006870-f5w6fw6q 4625 10 high high JJ cord-006870-f5w6fw6q 4625 11 mortality mortality NN cord-006870-f5w6fw6q 4625 12 and and CC cord-006870-f5w6fw6q 4625 13 morbidity morbidity NN cord-006870-f5w6fw6q 4625 14 , , , cord-006870-f5w6fw6q 4625 15 often often RB cord-006870-f5w6fw6q 4625 16 warranting warrant VBG cord-006870-f5w6fw6q 4625 17 an an DT cord-006870-f5w6fw6q 4625 18 aggressive aggressive JJ cord-006870-f5w6fw6q 4625 19 therapeutic therapeutic JJ cord-006870-f5w6fw6q 4625 20 approach approach NN cord-006870-f5w6fw6q 4625 21 . . . cord-006870-f5w6fw6q 4626 1 Initially initially RB cord-006870-f5w6fw6q 4626 2 used use VBN cord-006870-f5w6fw6q 4626 3 in in IN cord-006870-f5w6fw6q 4626 4 childhood childhood NN cord-006870-f5w6fw6q 4626 5 epilepsies epilepsy NNS cord-006870-f5w6fw6q 4626 6 , , , cord-006870-f5w6fw6q 4626 7 ketogenic ketogenic JJ cord-006870-f5w6fw6q 4626 8 diet diet NN cord-006870-f5w6fw6q 4626 9 ( ( -LRB- cord-006870-f5w6fw6q 4626 10 KD KD NNP cord-006870-f5w6fw6q 4626 11 ) ) -RRB- cord-006870-f5w6fw6q 4626 12 has have VBZ cord-006870-f5w6fw6q 4626 13 also also RB cord-006870-f5w6fw6q 4626 14 accumulated accumulate VBN cord-006870-f5w6fw6q 4626 15 supporting support VBG cord-006870-f5w6fw6q 4626 16 evidence evidence NN cord-006870-f5w6fw6q 4626 17 in in IN cord-006870-f5w6fw6q 4626 18 the the DT cord-006870-f5w6fw6q 4626 19 treatment treatment NN cord-006870-f5w6fw6q 4626 20 of of IN cord-006870-f5w6fw6q 4626 21 pediatric pediatric JJ cord-006870-f5w6fw6q 4626 22 SE se NN cord-006870-f5w6fw6q 4626 23 . . . cord-006870-f5w6fw6q 4627 1 Recently recently RB cord-006870-f5w6fw6q 4627 2 , , , cord-006870-f5w6fw6q 4627 3 the the DT cord-006870-f5w6fw6q 4627 4 implementation implementation NN cord-006870-f5w6fw6q 4627 5 of of IN cord-006870-f5w6fw6q 4627 6 KD KD NNP cord-006870-f5w6fw6q 4627 7 in in IN cord-006870-f5w6fw6q 4627 8 adults adult NNS cord-006870-f5w6fw6q 4627 9 with with IN cord-006870-f5w6fw6q 4627 10 refractory refractory JJ cord-006870-f5w6fw6q 4627 11 and and CC cord-006870-f5w6fw6q 4627 12 super super JJ cord-006870-f5w6fw6q 4627 13 - - JJ cord-006870-f5w6fw6q 4627 14 refractory refractory JJ cord-006870-f5w6fw6q 4627 15 SE SE NNP cord-006870-f5w6fw6q 4627 16 has have VBZ cord-006870-f5w6fw6q 4627 17 been be VBN cord-006870-f5w6fw6q 4627 18 shown show VBN cord-006870-f5w6fw6q 4627 19 to to TO cord-006870-f5w6fw6q 4627 20 be be VB cord-006870-f5w6fw6q 4627 21 feasible feasible JJ cord-006870-f5w6fw6q 4627 22 and and CC cord-006870-f5w6fw6q 4627 23 effective effective JJ cord-006870-f5w6fw6q 4627 24 . . . cord-006870-f5w6fw6q 4628 1 We -PRON- PRP cord-006870-f5w6fw6q 4628 2 describe describe VBP cord-006870-f5w6fw6q 4628 3 our -PRON- PRP$ cord-006870-f5w6fw6q 4628 4 recent recent JJ cord-006870-f5w6fw6q 4628 5 experience experience NN cord-006870-f5w6fw6q 4628 6 with with IN cord-006870-f5w6fw6q 4628 7 a a DT cord-006870-f5w6fw6q 4628 8 new new JJ cord-006870-f5w6fw6q 4628 9 onset onset NN cord-006870-f5w6fw6q 4628 10 refractory refractory JJ cord-006870-f5w6fw6q 4628 11 status status NN cord-006870-f5w6fw6q 4628 12 epilepticus epilepticus NN cord-006870-f5w6fw6q 4628 13 ( ( -LRB- cord-006870-f5w6fw6q 4628 14 NORSE NORSE NNP cord-006870-f5w6fw6q 4628 15 ) ) -RRB- cord-006870-f5w6fw6q 4628 16 patient patient NN cord-006870-f5w6fw6q 4628 17 and and CC cord-006870-f5w6fw6q 4628 18 the the DT cord-006870-f5w6fw6q 4628 19 unexpected unexpected JJ cord-006870-f5w6fw6q 4628 20 challenge challenge NN cord-006870-f5w6fw6q 4628 21 of of IN cord-006870-f5w6fw6q 4628 22 achieving achieve VBG cord-006870-f5w6fw6q 4628 23 and and CC cord-006870-f5w6fw6q 4628 24 maintaining maintain VBG cord-006870-f5w6fw6q 4628 25 a a DT cord-006870-f5w6fw6q 4628 26 ketotic ketotic JJ cord-006870-f5w6fw6q 4628 27 target target NN cord-006870-f5w6fw6q 4628 28 . . . cord-006870-f5w6fw6q 4629 1 Practical practical JJ cord-006870-f5w6fw6q 4629 2 advice advice NN cord-006870-f5w6fw6q 4629 3 , , , cord-006870-f5w6fw6q 4629 4 a a DT cord-006870-f5w6fw6q 4629 5 comprehensive comprehensive JJ cord-006870-f5w6fw6q 4629 6 review review NN cord-006870-f5w6fw6q 4629 7 of of IN cord-006870-f5w6fw6q 4629 8 offenders offender NNS cord-006870-f5w6fw6q 4629 9 jeopardizing jeopardize VBG cord-006870-f5w6fw6q 4629 10 ketosis ketosis NN cord-006870-f5w6fw6q 4629 11 commonly commonly RB cord-006870-f5w6fw6q 4629 12 used use VBN cord-006870-f5w6fw6q 4629 13 in in IN cord-006870-f5w6fw6q 4629 14 the the DT cord-006870-f5w6fw6q 4629 15 neurocritical neurocritical NNP cord-006870-f5w6fw6q 4629 16 care care NNP cord-006870-f5w6fw6q 4629 17 unit unit NN cord-006870-f5w6fw6q 4629 18 and and CC cord-006870-f5w6fw6q 4629 19 alternatives alternative NNS cord-006870-f5w6fw6q 4629 20 is be VBZ cord-006870-f5w6fw6q 4629 21 provided provide VBN cord-006870-f5w6fw6q 4629 22 . . . cord-006870-f5w6fw6q 4630 1 A a DT cord-006870-f5w6fw6q 4630 2 previously previously RB cord-006870-f5w6fw6q 4630 3 healthy healthy JJ cord-006870-f5w6fw6q 4630 4 29-year 29-year JJ cord-006870-f5w6fw6q 4630 5 - - HYPH cord-006870-f5w6fw6q 4630 6 old old JJ cord-006870-f5w6fw6q 4630 7 woman woman NN cord-006870-f5w6fw6q 4630 8 was be VBD cord-006870-f5w6fw6q 4630 9 admitted admit VBN cord-006870-f5w6fw6q 4630 10 with with IN cord-006870-f5w6fw6q 4630 11 cryptogenic cryptogenic NNP cord-006870-f5w6fw6q 4630 12 NORSE NORSE NNP cord-006870-f5w6fw6q 4630 13 following follow VBG cord-006870-f5w6fw6q 4630 14 a a DT cord-006870-f5w6fw6q 4630 15 febrile febrile JJ cord-006870-f5w6fw6q 4630 16 illness illness NN cord-006870-f5w6fw6q 4630 17 with with IN cord-006870-f5w6fw6q 4630 18 a a DT cord-006870-f5w6fw6q 4630 19 course course NN cord-006870-f5w6fw6q 4630 20 complicated complicate VBN cord-006870-f5w6fw6q 4630 21 by by IN cord-006870-f5w6fw6q 4630 22 prolonged prolonged JJ cord-006870-f5w6fw6q 4630 23 super super JJ cord-006870-f5w6fw6q 4630 24 - - JJ cord-006870-f5w6fw6q 4630 25 refractory refractory JJ cord-006870-f5w6fw6q 4630 26 SE se NN cord-006870-f5w6fw6q 4630 27 . . . cord-006870-f5w6fw6q 4631 1 A a DT cord-006870-f5w6fw6q 4631 2 comprehensive comprehensive JJ cord-006870-f5w6fw6q 4631 3 work work NN cord-006870-f5w6fw6q 4631 4 - - HYPH cord-006870-f5w6fw6q 4631 5 up up NN cord-006870-f5w6fw6q 4631 6 was be VBD cord-006870-f5w6fw6q 4631 7 notable notable JJ cord-006870-f5w6fw6q 4631 8 only only RB cord-006870-f5w6fw6q 4631 9 for for IN cord-006870-f5w6fw6q 4631 10 mild mild JJ cord-006870-f5w6fw6q 4631 11 cerebral cerebral JJ cord-006870-f5w6fw6q 4631 12 spinal spinal JJ cord-006870-f5w6fw6q 4631 13 fluid fluid NN cord-006870-f5w6fw6q 4631 14 ( ( -LRB- cord-006870-f5w6fw6q 4631 15 CSF CSF NNP cord-006870-f5w6fw6q 4631 16 ) ) -RRB- cord-006870-f5w6fw6q 4631 17 pleocytosis pleocytosis NNP cord-006870-f5w6fw6q 4631 18 , , , cord-006870-f5w6fw6q 4631 19 elevated elevated JJ cord-006870-f5w6fw6q 4631 20 non non JJ cord-006870-f5w6fw6q 4631 21 - - JJ cord-006870-f5w6fw6q 4631 22 specific specific JJ cord-006870-f5w6fw6q 4631 23 inflammatory inflammatory JJ cord-006870-f5w6fw6q 4631 24 serum serum NN cord-006870-f5w6fw6q 4631 25 markers marker NNS cord-006870-f5w6fw6q 4631 26 , , , cord-006870-f5w6fw6q 4631 27 and and CC cord-006870-f5w6fw6q 4631 28 edematous edematous JJ cord-006870-f5w6fw6q 4631 29 hippocampi hippocampus NNS cord-006870-f5w6fw6q 4631 30 with with IN cord-006870-f5w6fw6q 4631 31 associated associated JJ cord-006870-f5w6fw6q 4631 32 diffusion diffusion NN cord-006870-f5w6fw6q 4631 33 restriction restriction NN cord-006870-f5w6fw6q 4631 34 on on IN cord-006870-f5w6fw6q 4631 35 magnetic magnetic JJ cord-006870-f5w6fw6q 4631 36 resonance resonance NN cord-006870-f5w6fw6q 4631 37 imaging imaging NN cord-006870-f5w6fw6q 4631 38 ( ( -LRB- cord-006870-f5w6fw6q 4631 39 MRI MRI NNP cord-006870-f5w6fw6q 4631 40 ) ) -RRB- cord-006870-f5w6fw6q 4631 41 . . . cord-006870-f5w6fw6q 4632 1 Repeat repeat VB cord-006870-f5w6fw6q 4632 2 CSF CSF NNP cord-006870-f5w6fw6q 4632 3 testing testing NN cord-006870-f5w6fw6q 4632 4 was be VBD cord-006870-f5w6fw6q 4632 5 normal normal JJ cord-006870-f5w6fw6q 4632 6 and and CC cord-006870-f5w6fw6q 4632 7 serial serial JJ cord-006870-f5w6fw6q 4632 8 MRIs mri NNS cord-006870-f5w6fw6q 4632 9 demonstrated demonstrate VBD cord-006870-f5w6fw6q 4632 10 resolution resolution NN cord-006870-f5w6fw6q 4632 11 of of IN cord-006870-f5w6fw6q 4632 12 edema edema NN cord-006870-f5w6fw6q 4632 13 and and CC cord-006870-f5w6fw6q 4632 14 diffusion diffusion NN cord-006870-f5w6fw6q 4632 15 restriction restriction NN cord-006870-f5w6fw6q 4632 16 with with IN cord-006870-f5w6fw6q 4632 17 gradually gradually RB cord-006870-f5w6fw6q 4632 18 progressive progressive JJ cord-006870-f5w6fw6q 4632 19 hippocampal hippocampal NN cord-006870-f5w6fw6q 4632 20 and and CC cord-006870-f5w6fw6q 4632 21 diffuse diffuse JJ cord-006870-f5w6fw6q 4632 22 atrophy atrophy NN cord-006870-f5w6fw6q 4632 23 . . . cord-006870-f5w6fw6q 4633 1 She -PRON- PRP cord-006870-f5w6fw6q 4633 2 required require VBD cord-006870-f5w6fw6q 4633 3 an an DT cord-006870-f5w6fw6q 4633 4 aggressive aggressive JJ cord-006870-f5w6fw6q 4633 5 approach approach NN cord-006870-f5w6fw6q 4633 6 including include VBG cord-006870-f5w6fw6q 4633 7 high high JJ cord-006870-f5w6fw6q 4633 8 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4633 9 infusion infusion NN cord-006870-f5w6fw6q 4633 10 rates rate NNS cord-006870-f5w6fw6q 4633 11 , , , cord-006870-f5w6fw6q 4633 12 16 16 CD cord-006870-f5w6fw6q 4633 13 anti anti JJ cord-006870-f5w6fw6q 4633 14 - - JJ cord-006870-f5w6fw6q 4633 15 seizure seizure JJ cord-006870-f5w6fw6q 4633 16 drug drug NN cord-006870-f5w6fw6q 4633 17 trials trial NNS cord-006870-f5w6fw6q 4633 18 ( ( -LRB- cord-006870-f5w6fw6q 4633 19 in in IN cord-006870-f5w6fw6q 4633 20 various various JJ cord-006870-f5w6fw6q 4633 21 combinations combination NNS cord-006870-f5w6fw6q 4633 22 ) ) -RRB- cord-006870-f5w6fw6q 4633 23 , , , cord-006870-f5w6fw6q 4633 24 empiric empiric JJ cord-006870-f5w6fw6q 4633 25 partial partial JJ cord-006870-f5w6fw6q 4633 26 bilateral bilateral JJ cord-006870-f5w6fw6q 4633 27 oophorectomy oophorectomy NN cord-006870-f5w6fw6q 4633 28 , , , cord-006870-f5w6fw6q 4633 29 and and CC cord-006870-f5w6fw6q 4633 30 immunosuppression immunosuppression NN cord-006870-f5w6fw6q 4633 31 . . . cord-006870-f5w6fw6q 4634 1 Enteral enteral JJ cord-006870-f5w6fw6q 4634 2 ketogenic ketogenic JJ cord-006870-f5w6fw6q 4634 3 formula formula NN cord-006870-f5w6fw6q 4634 4 was be VBD cord-006870-f5w6fw6q 4634 5 started start VBN cord-006870-f5w6fw6q 4634 6 on on IN cord-006870-f5w6fw6q 4634 7 hospital hospital NN cord-006870-f5w6fw6q 4634 8 day day NN cord-006870-f5w6fw6q 4634 9 27 27 CD cord-006870-f5w6fw6q 4634 10 , , , cord-006870-f5w6fw6q 4634 11 however however RB cord-006870-f5w6fw6q 4634 12 , , , cord-006870-f5w6fw6q 4634 13 sustained sustained JJ cord-006870-f5w6fw6q 4634 14 beta beta NN cord-006870-f5w6fw6q 4634 15 - - HYPH cord-006870-f5w6fw6q 4634 16 hydroxybutyrate hydroxybutyrate NN cord-006870-f5w6fw6q 4634 17 levels level NNS cord-006870-f5w6fw6q 4635 1 > > XX cord-006870-f5w6fw6q 4636 1 2mmol 2mmol LS cord-006870-f5w6fw6q 4637 1 /L /L , cord-006870-f5w6fw6q 4637 2 were be VBD cord-006870-f5w6fw6q 4637 3 only only RB cord-006870-f5w6fw6q 4637 4 achieved achieve VBN cord-006870-f5w6fw6q 4637 5 37 37 CD cord-006870-f5w6fw6q 4637 6 days day NNS cord-006870-f5w6fw6q 4637 7 later later RB cord-006870-f5w6fw6q 4637 8 following follow VBG cord-006870-f5w6fw6q 4637 9 a a DT cord-006870-f5w6fw6q 4637 10 careful careful JJ cord-006870-f5w6fw6q 4637 11 comprehensive comprehensive JJ cord-006870-f5w6fw6q 4637 12 adjustment adjustment NN cord-006870-f5w6fw6q 4637 13 of of IN cord-006870-f5w6fw6q 4637 14 the the DT cord-006870-f5w6fw6q 4637 15 care care NN cord-006870-f5w6fw6q 4637 16 plan plan NN cord-006870-f5w6fw6q 4637 17 . . . cord-006870-f5w6fw6q 4638 1 Notably notably RB cord-006870-f5w6fw6q 4638 2 , , , cord-006870-f5w6fw6q 4638 3 a a DT cord-006870-f5w6fw6q 4638 4 significant significant JJ cord-006870-f5w6fw6q 4638 5 response response NN cord-006870-f5w6fw6q 4638 6 to to IN cord-006870-f5w6fw6q 4638 7 KD KD NNP cord-006870-f5w6fw6q 4638 8 was be VBD cord-006870-f5w6fw6q 4638 9 only only RB cord-006870-f5w6fw6q 4638 10 achieved achieve VBN cord-006870-f5w6fw6q 4638 11 with with IN cord-006870-f5w6fw6q 4638 12 beta beta JJ cord-006870-f5w6fw6q 4638 13 - - HYPH cord-006870-f5w6fw6q 4638 14 hydroxybutyrate hydroxybutyrate NN cord-006870-f5w6fw6q 4638 15 levels level NNS cord-006870-f5w6fw6q 4638 16 > > NFP cord-006870-f5w6fw6q 4638 17 3.5 3.5 CD cord-006870-f5w6fw6q 4638 18 mmol mmol VBN cord-006870-f5w6fw6q 4639 1 /L. /L. NFP cord-006870-f5w6fw6q 4639 2 There there EX cord-006870-f5w6fw6q 4639 3 are be VBP cord-006870-f5w6fw6q 4639 4 hidden hide VBN cord-006870-f5w6fw6q 4639 5 carbohydrates carbohydrate NNS cord-006870-f5w6fw6q 4639 6 in in IN cord-006870-f5w6fw6q 4639 7 commonly commonly RB cord-006870-f5w6fw6q 4639 8 administered administer VBN cord-006870-f5w6fw6q 4639 9 medications medication NNS cord-006870-f5w6fw6q 4639 10 for for IN cord-006870-f5w6fw6q 4639 11 SE SE NNP cord-006870-f5w6fw6q 4639 12 , , , cord-006870-f5w6fw6q 4639 13 antibiotics antibiotic NNS cord-006870-f5w6fw6q 4639 14 , , , cord-006870-f5w6fw6q 4639 15 and and CC cord-006870-f5w6fw6q 4639 16 even even RB cord-006870-f5w6fw6q 4639 17 electrolyte electrolyte JJ cord-006870-f5w6fw6q 4639 18 repletion repletion NN cord-006870-f5w6fw6q 4639 19 formulations formulation NNS cord-006870-f5w6fw6q 4639 20 and and CC cord-006870-f5w6fw6q 4639 21 solutions solution NNS cord-006870-f5w6fw6q 4639 22 used use VBN cord-006870-f5w6fw6q 4639 23 for for IN cord-006870-f5w6fw6q 4639 24 oral oral JJ cord-006870-f5w6fw6q 4639 25 care care NN cord-006870-f5w6fw6q 4639 26 -all -all : cord-006870-f5w6fw6q 4639 27 challenging challenge VBG cord-006870-f5w6fw6q 4639 28 the the DT cord-006870-f5w6fw6q 4639 29 use use NN cord-006870-f5w6fw6q 4639 30 of of IN cord-006870-f5w6fw6q 4639 31 KD KD NNP cord-006870-f5w6fw6q 4639 32 in in IN cord-006870-f5w6fw6q 4639 33 this this DT cord-006870-f5w6fw6q 4639 34 setting setting NN cord-006870-f5w6fw6q 4639 35 . . . cord-006870-f5w6fw6q 4640 1 Tailoring tailor VBG cord-006870-f5w6fw6q 4640 2 comprehensive comprehensive JJ cord-006870-f5w6fw6q 4640 3 care care NN cord-006870-f5w6fw6q 4640 4 and and CC cord-006870-f5w6fw6q 4640 5 being be VBG cord-006870-f5w6fw6q 4640 6 aware aware JJ cord-006870-f5w6fw6q 4640 7 of of IN cord-006870-f5w6fw6q 4640 8 possible possible JJ cord-006870-f5w6fw6q 4640 9 complications complication NNS cord-006870-f5w6fw6q 4640 10 of of IN cord-006870-f5w6fw6q 4640 11 KD KD NNP cord-006870-f5w6fw6q 4640 12 are be VBP cord-006870-f5w6fw6q 4640 13 important important JJ cord-006870-f5w6fw6q 4640 14 for for IN cord-006870-f5w6fw6q 4640 15 the the DT cord-006870-f5w6fw6q 4640 16 successful successful JJ cord-006870-f5w6fw6q 4640 17 implementation implementation NN cord-006870-f5w6fw6q 4640 18 and and CC cord-006870-f5w6fw6q 4640 19 maintenance maintenance NN cord-006870-f5w6fw6q 4640 20 of of IN cord-006870-f5w6fw6q 4640 21 ketosis ketosis NN cord-006870-f5w6fw6q 4640 22 . . . cord-006870-f5w6fw6q 4641 1 Early early JJ cord-006870-f5w6fw6q 4641 2 seizures seizure NNS cord-006870-f5w6fw6q 4641 3 are be VBP cord-006870-f5w6fw6q 4641 4 estimated estimate VBN cord-006870-f5w6fw6q 4641 5 to to TO cord-006870-f5w6fw6q 4641 6 occur occur VB cord-006870-f5w6fw6q 4641 7 in in IN cord-006870-f5w6fw6q 4641 8 18 18 CD cord-006870-f5w6fw6q 4641 9 - - SYM cord-006870-f5w6fw6q 4641 10 33 33 CD cord-006870-f5w6fw6q 4641 11 % % NN cord-006870-f5w6fw6q 4641 12 of of IN cord-006870-f5w6fw6q 4641 13 patients patient NNS cord-006870-f5w6fw6q 4641 14 with with IN cord-006870-f5w6fw6q 4641 15 moderate moderate JJ cord-006870-f5w6fw6q 4641 16 to to IN cord-006870-f5w6fw6q 4641 17 severe severe JJ cord-006870-f5w6fw6q 4641 18 traumatic traumatic JJ cord-006870-f5w6fw6q 4641 19 brain brain NN cord-006870-f5w6fw6q 4641 20 injury injury NN cord-006870-f5w6fw6q 4641 21 ( ( -LRB- cord-006870-f5w6fw6q 4641 22 TBI TBI NNP cord-006870-f5w6fw6q 4641 23 ) ) -RRB- cord-006870-f5w6fw6q 4641 24 ( ( -LRB- cord-006870-f5w6fw6q 4641 25 Herman Herman NNP cord-006870-f5w6fw6q 4641 26 2015 2015 CD cord-006870-f5w6fw6q 4641 27 , , , cord-006870-f5w6fw6q 4641 28 Vespa Vespa NNP cord-006870-f5w6fw6q 4641 29 1999 1999 CD cord-006870-f5w6fw6q 4641 30 ) ) -RRB- cord-006870-f5w6fw6q 4641 31 . . . cord-006870-f5w6fw6q 4642 1 Continuous continuous JJ cord-006870-f5w6fw6q 4642 2 EEG EEG NNP cord-006870-f5w6fw6q 4642 3 ( ( -LRB- cord-006870-f5w6fw6q 4642 4 cEEG ceeg JJ cord-006870-f5w6fw6q 4642 5 ) ) -RRB- cord-006870-f5w6fw6q 4642 6 is be VBZ cord-006870-f5w6fw6q 4642 7 essential essential JJ cord-006870-f5w6fw6q 4642 8 for for IN cord-006870-f5w6fw6q 4642 9 detection detection NN cord-006870-f5w6fw6q 4642 10 of of IN cord-006870-f5w6fw6q 4642 11 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 4642 12 seizures seizure NNS cord-006870-f5w6fw6q 4642 13 ( ( -LRB- cord-006870-f5w6fw6q 4642 14 Claassen Claassen NNP cord-006870-f5w6fw6q 4642 15 2004 2004 CD cord-006870-f5w6fw6q 4642 16 ) ) -RRB- cord-006870-f5w6fw6q 4643 1 The the DT cord-006870-f5w6fw6q 4643 2 University University NNP cord-006870-f5w6fw6q 4643 3 of of IN cord-006870-f5w6fw6q 4643 4 California California NNP cord-006870-f5w6fw6q 4643 5 Davis Davis NNP cord-006870-f5w6fw6q 4643 6 protocol protocol NN cord-006870-f5w6fw6q 4643 7 for for IN cord-006870-f5w6fw6q 4643 8 TBI TBI NNP cord-006870-f5w6fw6q 4643 9 includes include VBZ cord-006870-f5w6fw6q 4643 10 cEEG ceeg RB cord-006870-f5w6fw6q 4643 11 on on IN cord-006870-f5w6fw6q 4643 12 a a DT cord-006870-f5w6fw6q 4643 13 case case NN cord-006870-f5w6fw6q 4643 14 by by IN cord-006870-f5w6fw6q 4643 15 case case NN cord-006870-f5w6fw6q 4643 16 basis basis NN cord-006870-f5w6fw6q 4643 17 , , , cord-006870-f5w6fw6q 4643 18 which which WDT cord-006870-f5w6fw6q 4643 19 we -PRON- PRP cord-006870-f5w6fw6q 4643 20 reviewed review VBD cord-006870-f5w6fw6q 4643 21 . . . cord-006870-f5w6fw6q 4644 1 A a DT cord-006870-f5w6fw6q 4644 2 retrospective retrospective JJ cord-006870-f5w6fw6q 4644 3 review review NN cord-006870-f5w6fw6q 4644 4 of of IN cord-006870-f5w6fw6q 4644 5 patients patient NNS cord-006870-f5w6fw6q 4644 6 admitted admit VBN cord-006870-f5w6fw6q 4644 7 to to IN cord-006870-f5w6fw6q 4644 8 ICU ICU NNP cord-006870-f5w6fw6q 4644 9 for for IN cord-006870-f5w6fw6q 4644 10 TBI TBI NNP cord-006870-f5w6fw6q 4644 11 from from IN cord-006870-f5w6fw6q 4644 12 9/23/2016 9/23/2016 NNP cord-006870-f5w6fw6q 4644 13 - - : cord-006870-f5w6fw6q 4644 14 3/13/2017 3/13/2017 NNP cord-006870-f5w6fw6q 4644 15 was be VBD cord-006870-f5w6fw6q 4644 16 performed perform VBN cord-006870-f5w6fw6q 4644 17 for for IN cord-006870-f5w6fw6q 4644 18 demographics demographic NNS cord-006870-f5w6fw6q 4644 19 , , , cord-006870-f5w6fw6q 4644 20 ICU ICU NNP cord-006870-f5w6fw6q 4644 21 length length NN cord-006870-f5w6fw6q 4644 22 of of IN cord-006870-f5w6fw6q 4644 23 stay stay NN cord-006870-f5w6fw6q 4644 24 ( ( -LRB- cord-006870-f5w6fw6q 4644 25 LOS LOS NNP cord-006870-f5w6fw6q 4644 26 ) ) -RRB- cord-006870-f5w6fw6q 4644 27 , , , cord-006870-f5w6fw6q 4644 28 and and CC cord-006870-f5w6fw6q 4644 29 cEEG ceeg JJ cord-006870-f5w6fw6q 4644 30 . . . cord-006870-f5w6fw6q 4645 1 Patients patient NNS cord-006870-f5w6fw6q 4645 2 with with IN cord-006870-f5w6fw6q 4645 3 cEEG ceeg JJ cord-006870-f5w6fw6q 4645 4 were be VBD cord-006870-f5w6fw6q 4645 5 assessed assess VBN cord-006870-f5w6fw6q 4645 6 for for IN cord-006870-f5w6fw6q 4645 7 demographics demographic NNS cord-006870-f5w6fw6q 4645 8 , , , cord-006870-f5w6fw6q 4645 9 TBI TBI NNP cord-006870-f5w6fw6q 4645 10 severity severity NN cord-006870-f5w6fw6q 4645 11 , , , cord-006870-f5w6fw6q 4645 12 GCS GCS NNP cord-006870-f5w6fw6q 4645 13 , , , cord-006870-f5w6fw6q 4645 14 cEEG ceeg JJ cord-006870-f5w6fw6q 4645 15 indication indication NN cord-006870-f5w6fw6q 4645 16 and and CC cord-006870-f5w6fw6q 4645 17 findings finding NNS cord-006870-f5w6fw6q 4645 18 . . . cord-006870-f5w6fw6q 4646 1 100 100 CD cord-006870-f5w6fw6q 4646 2 patients patient NNS cord-006870-f5w6fw6q 4646 3 were be VBD cord-006870-f5w6fw6q 4646 4 identified identify VBN cord-006870-f5w6fw6q 4646 5 . . . cord-006870-f5w6fw6q 4647 1 Twenty twenty CD cord-006870-f5w6fw6q 4647 2 - - HYPH cord-006870-f5w6fw6q 4647 3 one one CD cord-006870-f5w6fw6q 4647 4 were be VBD cord-006870-f5w6fw6q 4647 5 monitored monitor VBN cord-006870-f5w6fw6q 4647 6 on on IN cord-006870-f5w6fw6q 4647 7 EEG EEG NNP cord-006870-f5w6fw6q 4647 8 . . . cord-006870-f5w6fw6q 4648 1 Median median JJ cord-006870-f5w6fw6q 4648 2 age age NN cord-006870-f5w6fw6q 4648 3 was be VBD cord-006870-f5w6fw6q 4648 4 36 36 CD cord-006870-f5w6fw6q 4648 5 , , , cord-006870-f5w6fw6q 4648 6 24 24 CD cord-006870-f5w6fw6q 4648 7 % % NN cord-006870-f5w6fw6q 4648 8 were be VBD cord-006870-f5w6fw6q 4648 9 female female JJ cord-006870-f5w6fw6q 4648 10 . . . cord-006870-f5w6fw6q 4649 1 Indications indication NNS cord-006870-f5w6fw6q 4649 2 for for IN cord-006870-f5w6fw6q 4649 3 cEEG ceeg JJ cord-006870-f5w6fw6q 4649 4 included include VBN cord-006870-f5w6fw6q 4649 5 seizure seizure NN cord-006870-f5w6fw6q 4649 6 prior prior RB cord-006870-f5w6fw6q 4649 7 to to IN cord-006870-f5w6fw6q 4649 8 admission admission NN cord-006870-f5w6fw6q 4649 9 ( ( -LRB- cord-006870-f5w6fw6q 4649 10 n=4 n=4 NNP cord-006870-f5w6fw6q 4649 11 ) ) -RRB- cord-006870-f5w6fw6q 4649 12 , , , cord-006870-f5w6fw6q 4649 13 altered alter VBN cord-006870-f5w6fw6q 4649 14 mental mental JJ cord-006870-f5w6fw6q 4649 15 status status NN cord-006870-f5w6fw6q 4649 16 ( ( -LRB- cord-006870-f5w6fw6q 4649 17 AMS AMS NNP cord-006870-f5w6fw6q 4649 18 ) ) -RRB- cord-006870-f5w6fw6q 4649 19 ( ( -LRB- cord-006870-f5w6fw6q 4649 20 n=13 n=13 NNP cord-006870-f5w6fw6q 4649 21 ) ) -RRB- cord-006870-f5w6fw6q 4649 22 , , , cord-006870-f5w6fw6q 4649 23 AMS AMS NNP cord-006870-f5w6fw6q 4649 24 with with IN cord-006870-f5w6fw6q 4649 25 paroxysmal paroxysmal JJ cord-006870-f5w6fw6q 4649 26 events event NNS cord-006870-f5w6fw6q 4649 27 ( ( -LRB- cord-006870-f5w6fw6q 4649 28 n=4 n=4 NNS cord-006870-f5w6fw6q 4649 29 ) ) -RRB- cord-006870-f5w6fw6q 4649 30 . . . cord-006870-f5w6fw6q 4650 1 Seizures seizure NNS cord-006870-f5w6fw6q 4650 2 were be VBD cord-006870-f5w6fw6q 4650 3 recorded record VBN cord-006870-f5w6fw6q 4650 4 in in IN cord-006870-f5w6fw6q 4650 5 2 2 CD cord-006870-f5w6fw6q 4650 6 patients patient NNS cord-006870-f5w6fw6q 4650 7 . . . cord-006870-f5w6fw6q 4651 1 Median median JJ cord-006870-f5w6fw6q 4651 2 duration duration NN cord-006870-f5w6fw6q 4651 3 of of IN cord-006870-f5w6fw6q 4651 4 cEEG ceeg NN cord-006870-f5w6fw6q 4651 5 was be VBD cord-006870-f5w6fw6q 4651 6 26.8 26.8 CD cord-006870-f5w6fw6q 4651 7 , , , cord-006870-f5w6fw6q 4651 8 296.36 296.36 CD cord-006870-f5w6fw6q 4651 9 , , , cord-006870-f5w6fw6q 4651 10 and and CC cord-006870-f5w6fw6q 4651 11 146.25 146.25 CD cord-006870-f5w6fw6q 4651 12 hours hour NNS cord-006870-f5w6fw6q 4651 13 among among IN cord-006870-f5w6fw6q 4651 14 the the DT cord-006870-f5w6fw6q 4651 15 groups group NNS cord-006870-f5w6fw6q 4651 16 . . . cord-006870-f5w6fw6q 4652 1 Those those DT cord-006870-f5w6fw6q 4652 2 with with IN cord-006870-f5w6fw6q 4652 3 seizures seizure NNS cord-006870-f5w6fw6q 4652 4 prior prior RB cord-006870-f5w6fw6q 4652 5 to to IN cord-006870-f5w6fw6q 4652 6 hospitalization hospitalization NN cord-006870-f5w6fw6q 4652 7 were be VBD cord-006870-f5w6fw6q 4652 8 connected connect VBN cord-006870-f5w6fw6q 4652 9 to to IN cord-006870-f5w6fw6q 4652 10 cEEG ceeg VB cord-006870-f5w6fw6q 4652 11 earliest early JJS cord-006870-f5w6fw6q 4652 12 ( ( -LRB- cord-006870-f5w6fw6q 4652 13 median median NN cord-006870-f5w6fw6q 4652 14 14 14 CD cord-006870-f5w6fw6q 4652 15 .65 .65 CD cord-006870-f5w6fw6q 4652 16 hours hour NNS cord-006870-f5w6fw6q 4652 17 ) ) -RRB- cord-006870-f5w6fw6q 4652 18 but but CC cord-006870-f5w6fw6q 4652 19 had have VBD cord-006870-f5w6fw6q 4652 20 the the DT cord-006870-f5w6fw6q 4652 21 longest long JJS cord-006870-f5w6fw6q 4652 22 median median JJ cord-006870-f5w6fw6q 4652 23 ICU ICU NNP cord-006870-f5w6fw6q 4652 24 LOS LOS NNP cord-006870-f5w6fw6q 4652 25 ( ( -LRB- cord-006870-f5w6fw6q 4652 26 623.27 623.27 CD cord-006870-f5w6fw6q 4652 27 hours hour NNS cord-006870-f5w6fw6q 4652 28 ) ) -RRB- cord-006870-f5w6fw6q 4652 29 , , , cord-006870-f5w6fw6q 4652 30 followed follow VBN cord-006870-f5w6fw6q 4652 31 by by IN cord-006870-f5w6fw6q 4652 32 AMS AMS NNP cord-006870-f5w6fw6q 4652 33 ( ( -LRB- cord-006870-f5w6fw6q 4652 34 40.28 40.28 CD cord-006870-f5w6fw6q 4652 35 and and CC cord-006870-f5w6fw6q 4652 36 424.92 424.92 CD cord-006870-f5w6fw6q 4652 37 hours hour NNS cord-006870-f5w6fw6q 4652 38 ) ) -RRB- cord-006870-f5w6fw6q 4652 39 and and CC cord-006870-f5w6fw6q 4652 40 AMS AMS NNP cord-006870-f5w6fw6q 4652 41 with with IN cord-006870-f5w6fw6q 4652 42 paroxysmal paroxysmal JJ cord-006870-f5w6fw6q 4652 43 events event NNS cord-006870-f5w6fw6q 4652 44 ( ( -LRB- cord-006870-f5w6fw6q 4652 45 78.83 78.83 CD cord-006870-f5w6fw6q 4652 46 and and CC cord-006870-f5w6fw6q 4652 47 377.88 377.88 CD cord-006870-f5w6fw6q 4652 48 hours hour NNS cord-006870-f5w6fw6q 4652 49 ) ) -RRB- cord-006870-f5w6fw6q 4652 50 . . . cord-006870-f5w6fw6q 4653 1 Median Median NNP cord-006870-f5w6fw6q 4653 2 GCS GCS NNP cord-006870-f5w6fw6q 4653 3 was be VBD cord-006870-f5w6fw6q 4653 4 3 3 CD cord-006870-f5w6fw6q 4653 5 , , , cord-006870-f5w6fw6q 4653 6 6 6 CD cord-006870-f5w6fw6q 4653 7 , , , cord-006870-f5w6fw6q 4653 8 and and CC cord-006870-f5w6fw6q 4653 9 5 5 CD cord-006870-f5w6fw6q 4653 10 respectively respectively RB cord-006870-f5w6fw6q 4653 11 . . . cord-006870-f5w6fw6q 4654 1 Median median JJ cord-006870-f5w6fw6q 4654 2 LOS LOS NNP cord-006870-f5w6fw6q 4654 3 for for IN cord-006870-f5w6fw6q 4654 4 patients patient NNS cord-006870-f5w6fw6q 4654 5 without without IN cord-006870-f5w6fw6q 4654 6 seizures seizure NNS cord-006870-f5w6fw6q 4654 7 or or CC cord-006870-f5w6fw6q 4654 8 interictal interictal JJ cord-006870-f5w6fw6q 4654 9 epileptiform epileptiform NNP cord-006870-f5w6fw6q 4654 10 activity activity NN cord-006870-f5w6fw6q 4654 11 ( ( -LRB- cord-006870-f5w6fw6q 4654 12 IEA IEA NNP cord-006870-f5w6fw6q 4654 13 ) ) -RRB- cord-006870-f5w6fw6q 4654 14 was be VBD cord-006870-f5w6fw6q 4654 15 380.63 380.63 CD cord-006870-f5w6fw6q 4654 16 hours hour NNS cord-006870-f5w6fw6q 4654 17 , , , cord-006870-f5w6fw6q 4654 18 483 483 CD cord-006870-f5w6fw6q 4654 19 . . . cord-006870-f5w6fw6q 4655 1 47 47 CD cord-006870-f5w6fw6q 4655 2 for for IN cord-006870-f5w6fw6q 4655 3 those those DT cord-006870-f5w6fw6q 4655 4 with with IN cord-006870-f5w6fw6q 4655 5 IEA IEA NNP cord-006870-f5w6fw6q 4655 6 only only RB cord-006870-f5w6fw6q 4655 7 , , , cord-006870-f5w6fw6q 4655 8 and and CC cord-006870-f5w6fw6q 4655 9 580.58 580.58 CD cord-006870-f5w6fw6q 4655 10 for for IN cord-006870-f5w6fw6q 4655 11 those those DT cord-006870-f5w6fw6q 4655 12 with with IN cord-006870-f5w6fw6q 4655 13 seizures seizure NNS cord-006870-f5w6fw6q 4655 14 . . . cord-006870-f5w6fw6q 4656 1 Median Median NNP cord-006870-f5w6fw6q 4656 2 GCS GCS NNP cord-006870-f5w6fw6q 4656 3 was be VBD cord-006870-f5w6fw6q 4656 4 4.5 4.5 CD cord-006870-f5w6fw6q 4656 5 , , , cord-006870-f5w6fw6q 4656 6 6 6 CD cord-006870-f5w6fw6q 4656 7 , , , cord-006870-f5w6fw6q 4656 8 and and CC cord-006870-f5w6fw6q 4656 9 4 4 CD cord-006870-f5w6fw6q 4656 10 among among IN cord-006870-f5w6fw6q 4656 11 the the DT cord-006870-f5w6fw6q 4656 12 EEG EEG NNP cord-006870-f5w6fw6q 4656 13 groupings grouping NNS cord-006870-f5w6fw6q 4656 14 . . . cord-006870-f5w6fw6q 4657 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4657 2 data data NN cord-006870-f5w6fw6q 4657 3 suggests suggest VBZ cord-006870-f5w6fw6q 4657 4 seizures seizure NNS cord-006870-f5w6fw6q 4657 5 prior prior RB cord-006870-f5w6fw6q 4657 6 to to IN cord-006870-f5w6fw6q 4657 7 hospitalization hospitalization NN cord-006870-f5w6fw6q 4657 8 , , , cord-006870-f5w6fw6q 4657 9 cEEG ceeg JJ cord-006870-f5w6fw6q 4657 10 recorded record VBN cord-006870-f5w6fw6q 4657 11 seizures seizure NNS cord-006870-f5w6fw6q 4657 12 , , , cord-006870-f5w6fw6q 4657 13 and and CC cord-006870-f5w6fw6q 4657 14 IEA IEA NNP cord-006870-f5w6fw6q 4657 15 predict predict VBP cord-006870-f5w6fw6q 4657 16 longer long JJR cord-006870-f5w6fw6q 4657 17 ICU ICU NNP cord-006870-f5w6fw6q 4657 18 LOS LOS NNP cord-006870-f5w6fw6q 4657 19 . . . cord-006870-f5w6fw6q 4658 1 Associated Associated NNP cord-006870-f5w6fw6q 4658 2 lower low JJR cord-006870-f5w6fw6q 4658 3 GCS GCS NNP cord-006870-f5w6fw6q 4658 4 likely likely RB cord-006870-f5w6fw6q 4658 5 indicates indicate VBZ cord-006870-f5w6fw6q 4658 6 more more RBR cord-006870-f5w6fw6q 4658 7 severe severe JJ cord-006870-f5w6fw6q 4658 8 injuries injury NNS cord-006870-f5w6fw6q 4658 9 . . . cord-006870-f5w6fw6q 4659 1 TBI TBI NNP cord-006870-f5w6fw6q 4659 2 patients patient NNS cord-006870-f5w6fw6q 4659 3 with with IN cord-006870-f5w6fw6q 4659 4 AMS AMS NNP cord-006870-f5w6fw6q 4659 5 may may MD cord-006870-f5w6fw6q 4659 6 have have VB cord-006870-f5w6fw6q 4659 7 delay delay NN cord-006870-f5w6fw6q 4659 8 to to IN cord-006870-f5w6fw6q 4659 9 seizure seizure NN cord-006870-f5w6fw6q 4659 10 detection detection NN cord-006870-f5w6fw6q 4659 11 and and CC cord-006870-f5w6fw6q 4659 12 treatment treatment NN cord-006870-f5w6fw6q 4659 13 . . . cord-006870-f5w6fw6q 4660 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4660 2 rate rate NN cord-006870-f5w6fw6q 4660 3 of of IN cord-006870-f5w6fw6q 4660 4 seizure seizure NN cord-006870-f5w6fw6q 4660 5 detection detection NN cord-006870-f5w6fw6q 4660 6 is be VBZ cord-006870-f5w6fw6q 4660 7 lower low JJR cord-006870-f5w6fw6q 4660 8 than than IN cord-006870-f5w6fw6q 4660 9 expected expect VBN cord-006870-f5w6fw6q 4660 10 . . . cord-006870-f5w6fw6q 4661 1 A a DT cord-006870-f5w6fw6q 4661 2 more more RBR cord-006870-f5w6fw6q 4661 3 consistent consistent JJ cord-006870-f5w6fw6q 4661 4 protocol protocol NN cord-006870-f5w6fw6q 4661 5 for for IN cord-006870-f5w6fw6q 4661 6 cEEG ceeg NN cord-006870-f5w6fw6q 4661 7 will will MD cord-006870-f5w6fw6q 4661 8 likely likely RB cord-006870-f5w6fw6q 4661 9 improve improve VB cord-006870-f5w6fw6q 4661 10 seizure seizure NN cord-006870-f5w6fw6q 4661 11 detection detection NN cord-006870-f5w6fw6q 4661 12 . . . cord-006870-f5w6fw6q 4662 1 Prospective prospective JJ cord-006870-f5w6fw6q 4662 2 studies study NNS cord-006870-f5w6fw6q 4662 3 are be VBP cord-006870-f5w6fw6q 4662 4 needed need VBN cord-006870-f5w6fw6q 4662 5 to to TO cord-006870-f5w6fw6q 4662 6 determine determine VB cord-006870-f5w6fw6q 4662 7 if if IN cord-006870-f5w6fw6q 4662 8 cEEG ceeg NN cord-006870-f5w6fw6q 4662 9 can can MD cord-006870-f5w6fw6q 4662 10 predict predict VB cord-006870-f5w6fw6q 4662 11 and and CC cord-006870-f5w6fw6q 4662 12 influence influence NN cord-006870-f5w6fw6q 4662 13 outcomes outcome NNS cord-006870-f5w6fw6q 4662 14 . . . cord-006870-f5w6fw6q 4663 1 Status status NN cord-006870-f5w6fw6q 4663 2 epilepticus epilepticus NN cord-006870-f5w6fw6q 4663 3 is be VBZ cord-006870-f5w6fw6q 4663 4 a a DT cord-006870-f5w6fw6q 4663 5 serious serious JJ cord-006870-f5w6fw6q 4663 6 neurologic neurologic JJ cord-006870-f5w6fw6q 4663 7 emergency emergency NN cord-006870-f5w6fw6q 4663 8 . . . cord-006870-f5w6fw6q 4664 1 Although although IN cord-006870-f5w6fw6q 4664 2 many many JJ cord-006870-f5w6fw6q 4664 3 studies study NNS cord-006870-f5w6fw6q 4664 4 have have VBP cord-006870-f5w6fw6q 4664 5 been be VBN cord-006870-f5w6fw6q 4664 6 published publish VBN cord-006870-f5w6fw6q 4664 7 on on IN cord-006870-f5w6fw6q 4664 8 incident incident NN cord-006870-f5w6fw6q 4664 9 status status NN cord-006870-f5w6fw6q 4664 10 epilepticus epilepticus NN cord-006870-f5w6fw6q 4664 11 , , , cord-006870-f5w6fw6q 4664 12 there there EX cord-006870-f5w6fw6q 4664 13 are be VBP cord-006870-f5w6fw6q 4664 14 few few JJ cord-006870-f5w6fw6q 4664 15 data datum NNS cord-006870-f5w6fw6q 4664 16 on on IN cord-006870-f5w6fw6q 4664 17 the the DT cord-006870-f5w6fw6q 4664 18 risk risk NN cord-006870-f5w6fw6q 4664 19 of of IN cord-006870-f5w6fw6q 4664 20 recurrent recurrent JJ cord-006870-f5w6fw6q 4664 21 status status NN cord-006870-f5w6fw6q 4664 22 epilepticus epilepticus NN cord-006870-f5w6fw6q 4664 23 . . . cord-006870-f5w6fw6q 4665 1 We -PRON- PRP cord-006870-f5w6fw6q 4665 2 performed perform VBD cord-006870-f5w6fw6q 4665 3 a a DT cord-006870-f5w6fw6q 4665 4 retrospective retrospective JJ cord-006870-f5w6fw6q 4665 5 cohort cohort NN cord-006870-f5w6fw6q 4665 6 study study NN cord-006870-f5w6fw6q 4665 7 using use VBG cord-006870-f5w6fw6q 4665 8 administrative administrative JJ cord-006870-f5w6fw6q 4665 9 claims claim NNS cord-006870-f5w6fw6q 4665 10 data datum NNS cord-006870-f5w6fw6q 4665 11 to to TO cord-006870-f5w6fw6q 4665 12 identify identify VB cord-006870-f5w6fw6q 4665 13 all all DT cord-006870-f5w6fw6q 4665 14 patients patient NNS cord-006870-f5w6fw6q 4665 15 hospitalized hospitalize VBN cord-006870-f5w6fw6q 4665 16 with with IN cord-006870-f5w6fw6q 4665 17 status status NN cord-006870-f5w6fw6q 4665 18 epilepticus epilepticus NN cord-006870-f5w6fw6q 4665 19 in in IN cord-006870-f5w6fw6q 4665 20 California California NNP cord-006870-f5w6fw6q 4665 21 , , , cord-006870-f5w6fw6q 4665 22 New New NNP cord-006870-f5w6fw6q 4665 23 York York NNP cord-006870-f5w6fw6q 4665 24 , , , cord-006870-f5w6fw6q 4665 25 and and CC cord-006870-f5w6fw6q 4665 26 Florida Florida NNP cord-006870-f5w6fw6q 4665 27 between between IN cord-006870-f5w6fw6q 4665 28 2005 2005 CD cord-006870-f5w6fw6q 4665 29 - - SYM cord-006870-f5w6fw6q 4665 30 2013 2013 CD cord-006870-f5w6fw6q 4665 31 . . . cord-006870-f5w6fw6q 4666 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4666 2 primary primary JJ cord-006870-f5w6fw6q 4666 3 outcome outcome NN cord-006870-f5w6fw6q 4666 4 was be VBD cord-006870-f5w6fw6q 4666 5 a a DT cord-006870-f5w6fw6q 4666 6 recurrent recurrent JJ cord-006870-f5w6fw6q 4666 7 hospitalization hospitalization NN cord-006870-f5w6fw6q 4666 8 for for IN cord-006870-f5w6fw6q 4666 9 status status NN cord-006870-f5w6fw6q 4666 10 epilepticus epilepticus NN cord-006870-f5w6fw6q 4666 11 . . . cord-006870-f5w6fw6q 4667 1 Survival survival NN cord-006870-f5w6fw6q 4667 2 statistics statistic NNS cord-006870-f5w6fw6q 4667 3 were be VBD cord-006870-f5w6fw6q 4667 4 used use VBN cord-006870-f5w6fw6q 4667 5 to to TO cord-006870-f5w6fw6q 4667 6 calculate calculate VB cord-006870-f5w6fw6q 4667 7 the the DT cord-006870-f5w6fw6q 4667 8 cumulative cumulative JJ cord-006870-f5w6fw6q 4667 9 rate rate NN cord-006870-f5w6fw6q 4667 10 of of IN cord-006870-f5w6fw6q 4667 11 recurrence recurrence NN cord-006870-f5w6fw6q 4667 12 at at IN cord-006870-f5w6fw6q 4667 13 30 30 CD cord-006870-f5w6fw6q 4667 14 days day NNS cord-006870-f5w6fw6q 4667 15 , , , cord-006870-f5w6fw6q 4667 16 1 1 CD cord-006870-f5w6fw6q 4667 17 year year NN cord-006870-f5w6fw6q 4667 18 , , , cord-006870-f5w6fw6q 4667 19 and and CC cord-006870-f5w6fw6q 4667 20 5 5 CD cord-006870-f5w6fw6q 4667 21 years year NNS cord-006870-f5w6fw6q 4667 22 . . . cord-006870-f5w6fw6q 4668 1 In in IN cord-006870-f5w6fw6q 4668 2 subgroup subgroup NN cord-006870-f5w6fw6q 4668 3 analyses analysis NNS cord-006870-f5w6fw6q 4668 4 , , , cord-006870-f5w6fw6q 4668 5 we -PRON- PRP cord-006870-f5w6fw6q 4668 6 compared compare VBD cord-006870-f5w6fw6q 4668 7 rates rate NNS cord-006870-f5w6fw6q 4668 8 of of IN cord-006870-f5w6fw6q 4668 9 recurrence recurrence NN cord-006870-f5w6fw6q 4668 10 according accord VBG cord-006870-f5w6fw6q 4668 11 to to IN cord-006870-f5w6fw6q 4668 12 age age NN cord-006870-f5w6fw6q 4668 13 , , , cord-006870-f5w6fw6q 4668 14 gender gender NN cord-006870-f5w6fw6q 4668 15 , , , cord-006870-f5w6fw6q 4668 16 race race NN cord-006870-f5w6fw6q 4668 17 , , , cord-006870-f5w6fw6q 4668 18 and and CC cord-006870-f5w6fw6q 4668 19 etiology etiology NN cord-006870-f5w6fw6q 4668 20 ( ( -LRB- cord-006870-f5w6fw6q 4668 21 stroke stroke NN cord-006870-f5w6fw6q 4668 22 , , , cord-006870-f5w6fw6q 4668 23 traumatic traumatic JJ cord-006870-f5w6fw6q 4668 24 brain brain NN cord-006870-f5w6fw6q 4668 25 injury injury NN cord-006870-f5w6fw6q 4668 26 , , , cord-006870-f5w6fw6q 4668 27 acute acute JJ cord-006870-f5w6fw6q 4668 28 and and CC cord-006870-f5w6fw6q 4668 29 chronic chronic JJ cord-006870-f5w6fw6q 4668 30 central central JJ cord-006870-f5w6fw6q 4668 31 nervous nervous JJ cord-006870-f5w6fw6q 4668 32 system system NN cord-006870-f5w6fw6q 4668 33 ( ( -LRB- cord-006870-f5w6fw6q 4668 34 CNS CNS NNP cord-006870-f5w6fw6q 4668 35 ) ) -RRB- cord-006870-f5w6fw6q 4668 36 infections infection NNS cord-006870-f5w6fw6q 4668 37 , , , cord-006870-f5w6fw6q 4668 38 brain brain NN cord-006870-f5w6fw6q 4668 39 tumors tumor NNS cord-006870-f5w6fw6q 4668 40 , , , cord-006870-f5w6fw6q 4668 41 dementia dementia NN cord-006870-f5w6fw6q 4668 42 , , , cord-006870-f5w6fw6q 4668 43 autoimmune autoimmune JJ cord-006870-f5w6fw6q 4668 44 CNS CNS NNP cord-006870-f5w6fw6q 4668 45 disease disease NN cord-006870-f5w6fw6q 4668 46 , , , cord-006870-f5w6fw6q 4668 47 or or CC cord-006870-f5w6fw6q 4668 48 unspecified unspecified JJ cord-006870-f5w6fw6q 4668 49 etiology etiology NN cord-006870-f5w6fw6q 4668 50 ) ) -RRB- cord-006870-f5w6fw6q 4668 51 . . . cord-006870-f5w6fw6q 4669 1 We -PRON- PRP cord-006870-f5w6fw6q 4669 2 identified identify VBD cord-006870-f5w6fw6q 4669 3 37,418 37,418 CD cord-006870-f5w6fw6q 4669 4 patients patient NNS cord-006870-f5w6fw6q 4669 5 with with IN cord-006870-f5w6fw6q 4669 6 status status NN cord-006870-f5w6fw6q 4669 7 epilepticus epilepticus NN cord-006870-f5w6fw6q 4669 8 . . . cord-006870-f5w6fw6q 4670 1 During during IN cord-006870-f5w6fw6q 4670 2 a a DT cord-006870-f5w6fw6q 4670 3 mean mean JJ cord-006870-f5w6fw6q 4670 4 follow follow NN cord-006870-f5w6fw6q 4670 5 - - HYPH cord-006870-f5w6fw6q 4670 6 up up NN cord-006870-f5w6fw6q 4670 7 of of IN cord-006870-f5w6fw6q 4670 8 2.9 2.9 CD cord-006870-f5w6fw6q 4670 9 ( ( -LRB- cord-006870-f5w6fw6q 4670 10 ±2.0 ±2.0 NNS cord-006870-f5w6fw6q 4670 11 ) ) -RRB- cord-006870-f5w6fw6q 4670 12 years year NNS cord-006870-f5w6fw6q 4670 13 , , , cord-006870-f5w6fw6q 4670 14 4,755 4,755 CD cord-006870-f5w6fw6q 4670 15 ( ( -LRB- cord-006870-f5w6fw6q 4670 16 12.7 12.7 CD cord-006870-f5w6fw6q 4670 17 % % NN cord-006870-f5w6fw6q 4670 18 ; ; : cord-006870-f5w6fw6q 4670 19 95 95 CD cord-006870-f5w6fw6q 4670 20 % % NN cord-006870-f5w6fw6q 4670 21 CI ci NN cord-006870-f5w6fw6q 4670 22 , , , cord-006870-f5w6fw6q 4670 23 12.4 12.4 CD cord-006870-f5w6fw6q 4670 24 - - SYM cord-006870-f5w6fw6q 4670 25 13.0 13.0 CD cord-006870-f5w6fw6q 4670 26 % % NN cord-006870-f5w6fw6q 4670 27 ) ) -RRB- cord-006870-f5w6fw6q 4670 28 developed develop VBN cord-006870-f5w6fw6q 4670 29 recurrent recurrent JJ cord-006870-f5w6fw6q 4670 30 status status NN cord-006870-f5w6fw6q 4670 31 epilepticus epilepticus NN cord-006870-f5w6fw6q 4670 32 . . . cord-006870-f5w6fw6q 4671 1 The the DT cord-006870-f5w6fw6q 4671 2 cumulative cumulative JJ cord-006870-f5w6fw6q 4671 3 rate rate NN cord-006870-f5w6fw6q 4671 4 of of IN cord-006870-f5w6fw6q 4671 5 recurrence recurrence NN cord-006870-f5w6fw6q 4671 6 was be VBD cord-006870-f5w6fw6q 4671 7 2.7 2.7 CD cord-006870-f5w6fw6q 4671 8 % % NN cord-006870-f5w6fw6q 4671 9 ( ( -LRB- cord-006870-f5w6fw6q 4671 10 95 95 CD cord-006870-f5w6fw6q 4671 11 % % NN cord-006870-f5w6fw6q 4671 12 CI CI NNP cord-006870-f5w6fw6q 4671 13 , , , cord-006870-f5w6fw6q 4671 14 2.5 2.5 CD cord-006870-f5w6fw6q 4671 15 - - SYM cord-006870-f5w6fw6q 4671 16 2.9 2.9 CD cord-006870-f5w6fw6q 4671 17 % % NN cord-006870-f5w6fw6q 4671 18 ) ) -RRB- cord-006870-f5w6fw6q 4671 19 at at IN cord-006870-f5w6fw6q 4671 20 30 30 CD cord-006870-f5w6fw6q 4671 21 days day NNS cord-006870-f5w6fw6q 4671 22 , , , cord-006870-f5w6fw6q 4671 23 10.9 10.9 CD cord-006870-f5w6fw6q 4671 24 % % NN cord-006870-f5w6fw6q 4671 25 ( ( -LRB- cord-006870-f5w6fw6q 4671 26 95 95 CD cord-006870-f5w6fw6q 4671 27 % % NN cord-006870-f5w6fw6q 4671 28 CI ci NN cord-006870-f5w6fw6q 4671 29 , , , cord-006870-f5w6fw6q 4671 30 10.5 10.5 CD cord-006870-f5w6fw6q 4671 31 - - SYM cord-006870-f5w6fw6q 4671 32 11.3 11.3 CD cord-006870-f5w6fw6q 4671 33 % % NN cord-006870-f5w6fw6q 4671 34 ) ) -RRB- cord-006870-f5w6fw6q 4671 35 at at IN cord-006870-f5w6fw6q 4671 36 1 1 CD cord-006870-f5w6fw6q 4671 37 year year NN cord-006870-f5w6fw6q 4671 38 , , , cord-006870-f5w6fw6q 4671 39 and and CC cord-006870-f5w6fw6q 4671 40 20.8 20.8 CD cord-006870-f5w6fw6q 4671 41 % % NN cord-006870-f5w6fw6q 4671 42 ( ( -LRB- cord-006870-f5w6fw6q 4671 43 95 95 CD cord-006870-f5w6fw6q 4671 44 % % NN cord-006870-f5w6fw6q 4671 45 CI CI NNP cord-006870-f5w6fw6q 4671 46 , , , cord-006870-f5w6fw6q 4671 47 20.2 20.2 CD cord-006870-f5w6fw6q 4671 48 - - SYM cord-006870-f5w6fw6q 4671 49 21.5 21.5 CD cord-006870-f5w6fw6q 4671 50 % % NN cord-006870-f5w6fw6q 4671 51 ) ) -RRB- cord-006870-f5w6fw6q 4671 52 at at IN cord-006870-f5w6fw6q 4671 53 5 5 CD cord-006870-f5w6fw6q 4671 54 years year NNS cord-006870-f5w6fw6q 4671 55 . . . cord-006870-f5w6fw6q 4672 1 The the DT cord-006870-f5w6fw6q 4672 2 5-year 5-year CD cord-006870-f5w6fw6q 4672 3 cumulative cumulative JJ cord-006870-f5w6fw6q 4672 4 rate rate NN cord-006870-f5w6fw6q 4672 5 of of IN cord-006870-f5w6fw6q 4672 6 recurrence recurrence NN cord-006870-f5w6fw6q 4672 7 was be VBD cord-006870-f5w6fw6q 4672 8 19.8 19.8 CD cord-006870-f5w6fw6q 4672 9 % % NN cord-006870-f5w6fw6q 4672 10 ( ( -LRB- cord-006870-f5w6fw6q 4672 11 95 95 CD cord-006870-f5w6fw6q 4672 12 % % NN cord-006870-f5w6fw6q 4672 13 CI CI NNP cord-006870-f5w6fw6q 4672 14 , , , cord-006870-f5w6fw6q 4672 15 18.9 18.9 CD cord-006870-f5w6fw6q 4672 16 - - SYM cord-006870-f5w6fw6q 4672 17 20.6 20.6 CD cord-006870-f5w6fw6q 4672 18 % % NN cord-006870-f5w6fw6q 4672 19 ) ) -RRB- cord-006870-f5w6fw6q 4672 20 in in IN cord-006870-f5w6fw6q 4672 21 women woman NNS cord-006870-f5w6fw6q 4672 22 versus versus IN cord-006870-f5w6fw6q 4672 23 21.9 21.9 CD cord-006870-f5w6fw6q 4672 24 % % NN cord-006870-f5w6fw6q 4672 25 ( ( -LRB- cord-006870-f5w6fw6q 4672 26 95 95 CD cord-006870-f5w6fw6q 4672 27 % % NN cord-006870-f5w6fw6q 4672 28 CI CI NNP cord-006870-f5w6fw6q 4672 29 , , , cord-006870-f5w6fw6q 4672 30 21.0 21.0 CD cord-006870-f5w6fw6q 4672 31 - - HYPH cord-006870-f5w6fw6q 4672 32 22.8 22.8 CD cord-006870-f5w6fw6q 4672 33 % % NN cord-006870-f5w6fw6q 4672 34 ) ) -RRB- cord-006870-f5w6fw6q 4672 35 in in IN cord-006870-f5w6fw6q 4672 36 men man NNS cord-006870-f5w6fw6q 4672 37 , , , cord-006870-f5w6fw6q 4672 38 16.8 16.8 CD cord-006870-f5w6fw6q 4672 39 % % NN cord-006870-f5w6fw6q 4672 40 ( ( -LRB- cord-006870-f5w6fw6q 4672 41 95 95 CD cord-006870-f5w6fw6q 4672 42 % % NN cord-006870-f5w6fw6q 4672 43 CI CI NNP cord-006870-f5w6fw6q 4672 44 , , , cord-006870-f5w6fw6q 4672 45 16.0 16.0 CD cord-006870-f5w6fw6q 4672 46 - - HYPH cord-006870-f5w6fw6q 4672 47 23.2 23.2 CD cord-006870-f5w6fw6q 4672 48 % % NN cord-006870-f5w6fw6q 4672 49 ( ( -LRB- cord-006870-f5w6fw6q 4672 50 95 95 CD cord-006870-f5w6fw6q 4672 51 % % NN cord-006870-f5w6fw6q 4672 52 CI CI NNP cord-006870-f5w6fw6q 4672 53 , , , cord-006870-f5w6fw6q 4672 54 22.4 22.4 CD cord-006870-f5w6fw6q 4672 55 - - SYM cord-006870-f5w6fw6q 4672 56 24.0 24.0 CD cord-006870-f5w6fw6q 4672 57 % % NN cord-006870-f5w6fw6q 4672 58 ) ) -RRB- cord-006870-f5w6fw6q 4672 59 in in IN cord-006870-f5w6fw6q 4672 60 patients patient NNS cord-006870-f5w6fw6q 4672 61 < < XX cord-006870-f5w6fw6q 4672 62 60 60 CD cord-006870-f5w6fw6q 4672 63 , , , cord-006870-f5w6fw6q 4672 64 and and CC cord-006870-f5w6fw6q 4672 65 19.1 19.1 CD cord-006870-f5w6fw6q 4672 66 % % NN cord-006870-f5w6fw6q 4672 67 ( ( -LRB- cord-006870-f5w6fw6q 4672 68 95 95 CD cord-006870-f5w6fw6q 4672 69 % % NN cord-006870-f5w6fw6q 4672 70 CI CI NNP cord-006870-f5w6fw6q 4672 71 , , , cord-006870-f5w6fw6q 4672 72 18.4 18.4 CD cord-006870-f5w6fw6q 4672 73 - - SYM cord-006870-f5w6fw6q 4672 74 19.9 19.9 CD cord-006870-f5w6fw6q 4672 75 % % NN cord-006870-f5w6fw6q 4672 76 ) ) -RRB- cord-006870-f5w6fw6q 4672 77 in in IN cord-006870-f5w6fw6q 4672 78 white white JJ cord-006870-f5w6fw6q 4672 79 patients patient NNS cord-006870-f5w6fw6q 4672 80 versus versus IN cord-006870-f5w6fw6q 4672 81 23.0 23.0 CD cord-006870-f5w6fw6q 4672 82 % % NN cord-006870-f5w6fw6q 4672 83 ( ( -LRB- cord-006870-f5w6fw6q 4672 84 95 95 CD cord-006870-f5w6fw6q 4672 85 % % NN cord-006870-f5w6fw6q 4672 86 CI CI NNP cord-006870-f5w6fw6q 4672 87 , , , cord-006870-f5w6fw6q 4672 88 22.1%-24.0 22.1%-24.0 CD cord-006870-f5w6fw6q 4672 89 % % NN cord-006870-f5w6fw6q 4672 90 ) ) -RRB- cord-006870-f5w6fw6q 4672 91 in in IN cord-006870-f5w6fw6q 4672 92 non non JJ cord-006870-f5w6fw6q 4672 93 - - JJ cord-006870-f5w6fw6q 4672 94 white white JJ cord-006870-f5w6fw6q 4672 95 patients patient NNS cord-006870-f5w6fw6q 4672 96 . . . cord-006870-f5w6fw6q 4673 1 The the DT cord-006870-f5w6fw6q 4673 2 5-year 5-year CD cord-006870-f5w6fw6q 4673 3 cumulative cumulative JJ cord-006870-f5w6fw6q 4673 4 rate rate NN cord-006870-f5w6fw6q 4673 5 of of IN cord-006870-f5w6fw6q 4673 6 recurrence recurrence NN cord-006870-f5w6fw6q 4673 7 was be VBD cord-006870-f5w6fw6q 4673 8 highest high JJS cord-006870-f5w6fw6q 4673 9 for for IN cord-006870-f5w6fw6q 4673 10 status status NN cord-006870-f5w6fw6q 4673 11 epilepticus epilepticus NN cord-006870-f5w6fw6q 4673 12 associated associate VBN cord-006870-f5w6fw6q 4673 13 with with IN cord-006870-f5w6fw6q 4673 14 autoimmune autoimmune JJ cord-006870-f5w6fw6q 4673 15 CNS CNS NNP cord-006870-f5w6fw6q 4673 16 disease disease NN cord-006870-f5w6fw6q 4673 17 ( ( -LRB- cord-006870-f5w6fw6q 4673 18 30.3 30.3 CD cord-006870-f5w6fw6q 4673 19 % % NN cord-006870-f5w6fw6q 4673 20 ; ; . cord-006870-f5w6fw6q 4674 1 95 95 CD cord-006870-f5w6fw6q 4674 2 % % NN cord-006870-f5w6fw6q 4674 3 CI CI NNP cord-006870-f5w6fw6q 4674 4 , , , cord-006870-f5w6fw6q 4674 5 25.4 25.4 CD cord-006870-f5w6fw6q 4674 6 - - HYPH cord-006870-f5w6fw6q 4674 7 35.9 35.9 CD cord-006870-f5w6fw6q 4674 8 % % NN cord-006870-f5w6fw6q 4674 9 ) ) -RRB- cord-006870-f5w6fw6q 4674 10 and and CC cord-006870-f5w6fw6q 4674 11 chronic chronic JJ cord-006870-f5w6fw6q 4674 12 CNS CNS NNP cord-006870-f5w6fw6q 4674 13 infection infection NN cord-006870-f5w6fw6q 4674 14 ( ( -LRB- cord-006870-f5w6fw6q 4674 15 24.1 24.1 CD cord-006870-f5w6fw6q 4674 16 % % NN cord-006870-f5w6fw6q 4674 17 ; ; : cord-006870-f5w6fw6q 4674 18 95 95 CD cord-006870-f5w6fw6q 4674 19 % % NN cord-006870-f5w6fw6q 4674 20 CI CI NNP cord-006870-f5w6fw6q 4674 21 , , , cord-006870-f5w6fw6q 4674 22 19.6 19.6 CD cord-006870-f5w6fw6q 4674 23 - - SYM cord-006870-f5w6fw6q 4674 24 29.4 29.4 CD cord-006870-f5w6fw6q 4674 25 % % NN cord-006870-f5w6fw6q 4674 26 ) ) -RRB- cord-006870-f5w6fw6q 4674 27 . . . cord-006870-f5w6fw6q 4675 1 Approximately approximately RB cord-006870-f5w6fw6q 4675 2 1 1 CD cord-006870-f5w6fw6q 4675 3 in in IN cord-006870-f5w6fw6q 4675 4 5 5 CD cord-006870-f5w6fw6q 4675 5 patients patient NNS cord-006870-f5w6fw6q 4675 6 with with IN cord-006870-f5w6fw6q 4675 7 status status NN cord-006870-f5w6fw6q 4675 8 epilepticus epilepticus NN cord-006870-f5w6fw6q 4675 9 experienced experience VBD cord-006870-f5w6fw6q 4675 10 a a DT cord-006870-f5w6fw6q 4675 11 recurrent recurrent JJ cord-006870-f5w6fw6q 4675 12 episode episode NN cord-006870-f5w6fw6q 4675 13 within within IN cord-006870-f5w6fw6q 4675 14 5 5 CD cord-006870-f5w6fw6q 4675 15 years year NNS cord-006870-f5w6fw6q 4675 16 . . . cord-006870-f5w6fw6q 4676 1 Recurrence recurrence NN cord-006870-f5w6fw6q 4676 2 was be VBD cord-006870-f5w6fw6q 4676 3 most most RBS cord-006870-f5w6fw6q 4676 4 often often RB cord-006870-f5w6fw6q 4676 5 seen see VBN cord-006870-f5w6fw6q 4676 6 in in IN cord-006870-f5w6fw6q 4676 7 younger young JJR cord-006870-f5w6fw6q 4676 8 patients patient NNS cord-006870-f5w6fw6q 4676 9 , , , cord-006870-f5w6fw6q 4676 10 non non JJ cord-006870-f5w6fw6q 4676 11 - - JJ cord-006870-f5w6fw6q 4676 12 white white JJ cord-006870-f5w6fw6q 4676 13 patients patient NNS cord-006870-f5w6fw6q 4676 14 , , , cord-006870-f5w6fw6q 4676 15 and and CC cord-006870-f5w6fw6q 4676 16 patients patient NNS cord-006870-f5w6fw6q 4676 17 with with IN cord-006870-f5w6fw6q 4676 18 underlying underlying JJ cord-006870-f5w6fw6q 4676 19 autoimmune autoimmune JJ cord-006870-f5w6fw6q 4676 20 CNS CNS NNP cord-006870-f5w6fw6q 4676 21 disease disease NN cord-006870-f5w6fw6q 4676 22 or or CC cord-006870-f5w6fw6q 4676 23 chronic chronic JJ cord-006870-f5w6fw6q 4676 24 CNS CNS NNP cord-006870-f5w6fw6q 4676 25 infection infection NN cord-006870-f5w6fw6q 4676 26 . . . cord-006870-f5w6fw6q 4677 1 Super super JJ cord-006870-f5w6fw6q 4677 2 - - JJ cord-006870-f5w6fw6q 4677 3 refractory refractory JJ cord-006870-f5w6fw6q 4677 4 status status NN cord-006870-f5w6fw6q 4677 5 epilepticus epilepticus NN cord-006870-f5w6fw6q 4677 6 ( ( -LRB- cord-006870-f5w6fw6q 4677 7 SRSE SRSE NNP cord-006870-f5w6fw6q 4677 8 ) ) -RRB- cord-006870-f5w6fw6q 4677 9 is be VBZ cord-006870-f5w6fw6q 4677 10 a a DT cord-006870-f5w6fw6q 4677 11 rare rare JJ cord-006870-f5w6fw6q 4677 12 , , , cord-006870-f5w6fw6q 4677 13 life life NN cord-006870-f5w6fw6q 4677 14 - - HYPH cord-006870-f5w6fw6q 4677 15 threatening threaten VBG cord-006870-f5w6fw6q 4677 16 form form NN cord-006870-f5w6fw6q 4677 17 of of IN cord-006870-f5w6fw6q 4677 18 status status NN cord-006870-f5w6fw6q 4677 19 epilepticus epilepticus NN cord-006870-f5w6fw6q 4677 20 ( ( -LRB- cord-006870-f5w6fw6q 4677 21 SE SE NNP cord-006870-f5w6fw6q 4677 22 ) ) -RRB- cord-006870-f5w6fw6q 4677 23 refractory refractory JJ cord-006870-f5w6fw6q 4677 24 to to IN cord-006870-f5w6fw6q 4677 25 multiple multiple JJ cord-006870-f5w6fw6q 4677 26 therapies therapy NNS cord-006870-f5w6fw6q 4677 27 including include VBG cord-006870-f5w6fw6q 4677 28 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4677 29 third third JJ cord-006870-f5w6fw6q 4677 30 - - HYPH cord-006870-f5w6fw6q 4677 31 line line NN cord-006870-f5w6fw6q 4677 32 agents agent NNS cord-006870-f5w6fw6q 4677 33 ( ( -LRB- cord-006870-f5w6fw6q 4677 34 TLAs TLAs NNP cord-006870-f5w6fw6q 4677 35 ) ) -RRB- cord-006870-f5w6fw6q 4677 36 . . . cord-006870-f5w6fw6q 4678 1 Enrollment enrollment NN cord-006870-f5w6fw6q 4678 2 in in IN cord-006870-f5w6fw6q 4678 3 a a DT cord-006870-f5w6fw6q 4678 4 SRSE SRSE NNP cord-006870-f5w6fw6q 4678 5 clinical clinical JJ cord-006870-f5w6fw6q 4678 6 trial trial NN cord-006870-f5w6fw6q 4678 7 is be VBZ cord-006870-f5w6fw6q 4678 8 challenging challenging JJ cord-006870-f5w6fw6q 4678 9 because because IN cord-006870-f5w6fw6q 4678 10 patients patient NNS cord-006870-f5w6fw6q 4678 11 may may MD cord-006870-f5w6fw6q 4678 12 present present VB cord-006870-f5w6fw6q 4678 13 urgently urgently RB cord-006870-f5w6fw6q 4678 14 before before IN cord-006870-f5w6fw6q 4678 15 SRSE SRSE NNP cord-006870-f5w6fw6q 4678 16 is be VBZ cord-006870-f5w6fw6q 4678 17 confirmed confirm VBN cord-006870-f5w6fw6q 4678 18 or or CC cord-006870-f5w6fw6q 4678 19 may may MD cord-006870-f5w6fw6q 4678 20 dynamically dynamically RB cord-006870-f5w6fw6q 4678 21 improve improve VB cord-006870-f5w6fw6q 4678 22 before before IN cord-006870-f5w6fw6q 4678 23 randomization randomization NN cord-006870-f5w6fw6q 4678 24 . . . cord-006870-f5w6fw6q 4679 1 Pivotal pivotal JJ cord-006870-f5w6fw6q 4679 2 clinical clinical JJ cord-006870-f5w6fw6q 4679 3 trials trial NNS cord-006870-f5w6fw6q 4679 4 in in IN cord-006870-f5w6fw6q 4679 5 SRSE SRSE NNP cord-006870-f5w6fw6q 4679 6 require require VBP cord-006870-f5w6fw6q 4679 7 patient patient JJ cord-006870-f5w6fw6q 4679 8 selection selection NN cord-006870-f5w6fw6q 4679 9 criteria criterion NNS cord-006870-f5w6fw6q 4679 10 accurately accurately RB cord-006870-f5w6fw6q 4679 11 identifying identify VBG cord-006870-f5w6fw6q 4679 12 SRSE SRSE NNP cord-006870-f5w6fw6q 4679 13 at at IN cord-006870-f5w6fw6q 4679 14 randomization randomization NN cord-006870-f5w6fw6q 4679 15 . . . cord-006870-f5w6fw6q 4680 1 In in IN cord-006870-f5w6fw6q 4680 2 this this DT cord-006870-f5w6fw6q 4680 3 Phase phase NN cord-006870-f5w6fw6q 4680 4 3 3 CD cord-006870-f5w6fw6q 4680 5 trial trial NN cord-006870-f5w6fw6q 4680 6 of of IN cord-006870-f5w6fw6q 4680 7 brexanolone brexanolone NNP cord-006870-f5w6fw6q 4680 8 as as IN cord-006870-f5w6fw6q 4680 9 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4680 10 therapy therapy NN cord-006870-f5w6fw6q 4680 11 for for IN cord-006870-f5w6fw6q 4680 12 confirmed confirm VBN cord-006870-f5w6fw6q 4680 13 SRSE SRSE NNP cord-006870-f5w6fw6q 4680 14 , , , cord-006870-f5w6fw6q 4680 15 the the DT cord-006870-f5w6fw6q 4680 16 enrollment enrollment NN cord-006870-f5w6fw6q 4680 17 scheme scheme NN cord-006870-f5w6fw6q 4680 18 enabled enable VBD cord-006870-f5w6fw6q 4680 19 operationally operationally RB cord-006870-f5w6fw6q 4680 20 confirming confirm VBG cord-006870-f5w6fw6q 4680 21 SRSE SRSE NNP cord-006870-f5w6fw6q 4680 22 prior prior RB cord-006870-f5w6fw6q 4680 23 to to IN cord-006870-f5w6fw6q 4680 24 randomization randomization NN cord-006870-f5w6fw6q 4680 25 during during IN cord-006870-f5w6fw6q 4680 26 a a DT cord-006870-f5w6fw6q 4680 27 qualifying qualifying NN cord-006870-f5w6fw6q 4680 28 wean wean NN cord-006870-f5w6fw6q 4680 29 ( ( -LRB- cord-006870-f5w6fw6q 4680 30 QW qw VB cord-006870-f5w6fw6q 4680 31 ) ) -RRB- cord-006870-f5w6fw6q 4680 32 under under IN cord-006870-f5w6fw6q 4680 33 real real JJ cord-006870-f5w6fw6q 4680 34 - - HYPH cord-006870-f5w6fw6q 4680 35 time time NN cord-006870-f5w6fw6q 4680 36 EEG EEG NNP cord-006870-f5w6fw6q 4680 37 neuromonitoring neuromonitoring NN cord-006870-f5w6fw6q 4680 38 . . . cord-006870-f5w6fw6q 4681 1 Informed informed JJ cord-006870-f5w6fw6q 4681 2 consent consent NN cord-006870-f5w6fw6q 4681 3 was be VBD cord-006870-f5w6fw6q 4681 4 obtained obtain VBN cord-006870-f5w6fw6q 4681 5 for for IN cord-006870-f5w6fw6q 4681 6 all all DT cord-006870-f5w6fw6q 4681 7 subjects subject NNS cord-006870-f5w6fw6q 4681 8 1 1 CD cord-006870-f5w6fw6q 4681 9 ) ) -RRB- cord-006870-f5w6fw6q 4681 10 admitted admit VBN cord-006870-f5w6fw6q 4681 11 in in IN cord-006870-f5w6fw6q 4681 12 SE SE NNP cord-006870-f5w6fw6q 4681 13 having have VBG cord-006870-f5w6fw6q 4681 14 failed fail VBN cord-006870-f5w6fw6q 4681 15 first first JJ cord-006870-f5w6fw6q 4681 16 - - HYPH cord-006870-f5w6fw6q 4681 17 and and CC cord-006870-f5w6fw6q 4681 18 second second JJ cord-006870-f5w6fw6q 4681 19 - - HYPH cord-006870-f5w6fw6q 4681 20 line line NN cord-006870-f5w6fw6q 4681 21 therapies therapy NNS cord-006870-f5w6fw6q 4681 22 ; ; : cord-006870-f5w6fw6q 4681 23 2 2 LS cord-006870-f5w6fw6q 4681 24 ) ) -RRB- cord-006870-f5w6fw6q 4681 25 transferred transfer VBN cord-006870-f5w6fw6q 4681 26 on on IN cord-006870-f5w6fw6q 4681 27 TLAs tla NNS cord-006870-f5w6fw6q 4681 28 in in IN cord-006870-f5w6fw6q 4681 29 seizure seizure NN cord-006870-f5w6fw6q 4681 30 - - : cord-006870-f5w6fw6q 4681 31 or or CC cord-006870-f5w6fw6q 4681 32 burst burst NN cord-006870-f5w6fw6q 4681 33 - - HYPH cord-006870-f5w6fw6q 4681 34 suppression suppression NN cord-006870-f5w6fw6q 4681 35 ; ; : cord-006870-f5w6fw6q 4681 36 or or CC cord-006870-f5w6fw6q 4681 37 3 3 LS cord-006870-f5w6fw6q 4681 38 ) ) -RRB- cord-006870-f5w6fw6q 4681 39 transferred transfer VBN cord-006870-f5w6fw6q 4681 40 without without IN cord-006870-f5w6fw6q 4681 41 seizure seizure NN cord-006870-f5w6fw6q 4681 42 - - : cord-006870-f5w6fw6q 4681 43 or or CC cord-006870-f5w6fw6q 4681 44 burst burst NN cord-006870-f5w6fw6q 4681 45 - - HYPH cord-006870-f5w6fw6q 4681 46 suppression suppression NN cord-006870-f5w6fw6q 4681 47 or or CC cord-006870-f5w6fw6q 4681 48 not not RB cord-006870-f5w6fw6q 4681 49 receiving receive VBG cord-006870-f5w6fw6q 4681 50 TLAs tla NNS cord-006870-f5w6fw6q 4681 51 . . . cord-006870-f5w6fw6q 4682 1 Subjects subject NNS cord-006870-f5w6fw6q 4682 2 were be VBD cord-006870-f5w6fw6q 4682 3 required require VBN cord-006870-f5w6fw6q 4682 4 to to TO cord-006870-f5w6fw6q 4682 5 achieve achieve VB cord-006870-f5w6fw6q 4682 6 seizure seizure NN cord-006870-f5w6fw6q 4682 7 - - : cord-006870-f5w6fw6q 4682 8 or or CC cord-006870-f5w6fw6q 4682 9 burst burst NN cord-006870-f5w6fw6q 4682 10 - - HYPH cord-006870-f5w6fw6q 4682 11 suppression suppression NN cord-006870-f5w6fw6q 4682 12 for for IN cord-006870-f5w6fw6q 4682 13 24 24 CD cord-006870-f5w6fw6q 4682 14 hours hour NNS cord-006870-f5w6fw6q 4682 15 through through IN cord-006870-f5w6fw6q 4682 16 continuous continuous JJ cord-006870-f5w6fw6q 4682 17 administration administration NN cord-006870-f5w6fw6q 4682 18 of of IN cord-006870-f5w6fw6q 4682 19 one one CD cord-006870-f5w6fw6q 4682 20 or or CC cord-006870-f5w6fw6q 4682 21 more more JJR cord-006870-f5w6fw6q 4682 22 TLAs tla NNS cord-006870-f5w6fw6q 4682 23 , , , cord-006870-f5w6fw6q 4682 24 followed follow VBN cord-006870-f5w6fw6q 4682 25 by by IN cord-006870-f5w6fw6q 4682 26 a a DT cord-006870-f5w6fw6q 4682 27 post post JJ cord-006870-f5w6fw6q 4682 28 - - JJ cord-006870-f5w6fw6q 4682 29 enrollment enrollment NN cord-006870-f5w6fw6q 4682 30 QW qw NN cord-006870-f5w6fw6q 4682 31 of of IN cord-006870-f5w6fw6q 4682 32 TLAs tla NNS cord-006870-f5w6fw6q 4682 33 . . . cord-006870-f5w6fw6q 4683 1 Enrolled enrol VBN cord-006870-f5w6fw6q 4683 2 subjects subject NNS cord-006870-f5w6fw6q 4683 3 failing fail VBG cord-006870-f5w6fw6q 4683 4 the the DT cord-006870-f5w6fw6q 4683 5 QW QW NNP cord-006870-f5w6fw6q 4683 6 were be VBD cord-006870-f5w6fw6q 4683 7 randomized randomize VBN cord-006870-f5w6fw6q 4683 8 to to IN cord-006870-f5w6fw6q 4683 9 concomitant concomitant JJ cord-006870-f5w6fw6q 4683 10 brexanolone brexanolone NN cord-006870-f5w6fw6q 4683 11 or or CC cord-006870-f5w6fw6q 4683 12 placebo placebo NN cord-006870-f5w6fw6q 4683 13 following follow VBG cord-006870-f5w6fw6q 4683 14 reinstitution reinstitution NN cord-006870-f5w6fw6q 4683 15 of of IN cord-006870-f5w6fw6q 4683 16 one one CD cord-006870-f5w6fw6q 4683 17 or or CC cord-006870-f5w6fw6q 4683 18 more more JJR cord-006870-f5w6fw6q 4683 19 TLAs tla NNS cord-006870-f5w6fw6q 4683 20 . . . cord-006870-f5w6fw6q 4684 1 Subjects subject NNS cord-006870-f5w6fw6q 4684 2 not not RB cord-006870-f5w6fw6q 4684 3 randomized randomize VBN cord-006870-f5w6fw6q 4684 4 after after IN cord-006870-f5w6fw6q 4684 5 a a DT cord-006870-f5w6fw6q 4684 6 successful successful JJ cord-006870-f5w6fw6q 4684 7 QW QW NNP cord-006870-f5w6fw6q 4684 8 underwent undergo VBD cord-006870-f5w6fw6q 4684 9 a a DT cord-006870-f5w6fw6q 4684 10 3-week 3-week CD cord-006870-f5w6fw6q 4684 11 follow follow NN cord-006870-f5w6fw6q 4684 12 - - HYPH cord-006870-f5w6fw6q 4684 13 up up NN cord-006870-f5w6fw6q 4684 14 . . . cord-006870-f5w6fw6q 4685 1 The the DT cord-006870-f5w6fw6q 4685 2 QW QW NNP cord-006870-f5w6fw6q 4685 3 protocol protocol NN cord-006870-f5w6fw6q 4685 4 and and CC cord-006870-f5w6fw6q 4685 5 criteria criterion NNS cord-006870-f5w6fw6q 4685 6 for for IN cord-006870-f5w6fw6q 4685 7 QW QW NNP cord-006870-f5w6fw6q 4685 8 failure failure NN cord-006870-f5w6fw6q 4685 9 were be VBD cord-006870-f5w6fw6q 4685 10 developed develop VBN cord-006870-f5w6fw6q 4685 11 and and CC cord-006870-f5w6fw6q 4685 12 implemented implement VBN cord-006870-f5w6fw6q 4685 13 utilizing utilize VBG cord-006870-f5w6fw6q 4685 14 EEG EEG NNP cord-006870-f5w6fw6q 4685 15 neuromonitoring neuromonitore VBG cord-006870-f5w6fw6q 4685 16 to to TO cord-006870-f5w6fw6q 4685 17 confirm confirm VB cord-006870-f5w6fw6q 4685 18 SRSE SRSE NNP cord-006870-f5w6fw6q 4685 19 after after IN cord-006870-f5w6fw6q 4685 20 enrollment enrollment NN cord-006870-f5w6fw6q 4685 21 using use VBG cord-006870-f5w6fw6q 4685 22 the the DT cord-006870-f5w6fw6q 4685 23 definition definition NN cord-006870-f5w6fw6q 4685 24 of of IN cord-006870-f5w6fw6q 4685 25 Shorvon Shorvon NNP cord-006870-f5w6fw6q 4685 26 and and CC cord-006870-f5w6fw6q 4685 27 colleagues colleague NNS cord-006870-f5w6fw6q 4685 28 . . . cord-006870-f5w6fw6q 4686 1 A a DT cord-006870-f5w6fw6q 4686 2 QW qw NN cord-006870-f5w6fw6q 4686 3 was be VBD cord-006870-f5w6fw6q 4686 4 performed perform VBN cord-006870-f5w6fw6q 4686 5 on on IN cord-006870-f5w6fw6q 4686 6 over over IN cord-006870-f5w6fw6q 4686 7 100 100 CD cord-006870-f5w6fw6q 4686 8 evaluable evaluable JJ cord-006870-f5w6fw6q 4686 9 subjects subject NNS cord-006870-f5w6fw6q 4686 10 across across IN cord-006870-f5w6fw6q 4686 11 180 180 CD cord-006870-f5w6fw6q 4686 12 international international JJ cord-006870-f5w6fw6q 4686 13 sites site NNS cord-006870-f5w6fw6q 4686 14 to to TO cord-006870-f5w6fw6q 4686 15 enable enable VB cord-006870-f5w6fw6q 4686 16 enrollment enrollment NN cord-006870-f5w6fw6q 4686 17 of of IN cord-006870-f5w6fw6q 4686 18 patients patient NNS cord-006870-f5w6fw6q 4686 19 with with IN cord-006870-f5w6fw6q 4686 20 confirmed confirm VBN cord-006870-f5w6fw6q 4686 21 SRSE SRSE NNP cord-006870-f5w6fw6q 4686 22 . . . cord-006870-f5w6fw6q 4687 1 Subjects subject NNS cord-006870-f5w6fw6q 4687 2 with with IN cord-006870-f5w6fw6q 4687 3 a a DT cord-006870-f5w6fw6q 4687 4 successful successful JJ cord-006870-f5w6fw6q 4687 5 QWs qw NNS cord-006870-f5w6fw6q 4687 6 who who WP cord-006870-f5w6fw6q 4687 7 were be VBD cord-006870-f5w6fw6q 4687 8 not not RB cord-006870-f5w6fw6q 4687 9 randomized randomize VBN cord-006870-f5w6fw6q 4687 10 provided provide VBN cord-006870-f5w6fw6q 4687 11 insight insight NN cord-006870-f5w6fw6q 4687 12 into into IN cord-006870-f5w6fw6q 4687 13 outcomes outcome NNS cord-006870-f5w6fw6q 4687 14 associated associate VBN cord-006870-f5w6fw6q 4687 15 with with IN cord-006870-f5w6fw6q 4687 16 SE SE NNP cord-006870-f5w6fw6q 4687 17 and and CC cord-006870-f5w6fw6q 4687 18 avoided avoid VBD cord-006870-f5w6fw6q 4687 19 the the DT cord-006870-f5w6fw6q 4687 20 randomization randomization NN cord-006870-f5w6fw6q 4687 21 of of IN cord-006870-f5w6fw6q 4687 22 patients patient NNS cord-006870-f5w6fw6q 4687 23 who who WP cord-006870-f5w6fw6q 4687 24 did do VBD cord-006870-f5w6fw6q 4687 25 not not RB cord-006870-f5w6fw6q 4687 26 meet meet VB cord-006870-f5w6fw6q 4687 27 SRSE SRSE NNP cord-006870-f5w6fw6q 4687 28 criteria criterion NNS cord-006870-f5w6fw6q 4687 29 following follow VBG cord-006870-f5w6fw6q 4687 30 enrollment enrollment NN cord-006870-f5w6fw6q 4687 31 . . . cord-006870-f5w6fw6q 4688 1 The the DT cord-006870-f5w6fw6q 4688 2 use use NN cord-006870-f5w6fw6q 4688 3 of of IN cord-006870-f5w6fw6q 4688 4 neuromonitoring neuromonitore VBG cord-006870-f5w6fw6q 4688 5 - - HYPH cord-006870-f5w6fw6q 4688 6 guided guide VBN cord-006870-f5w6fw6q 4688 7 diagnosis diagnosis NN cord-006870-f5w6fw6q 4688 8 during during IN cord-006870-f5w6fw6q 4688 9 a a DT cord-006870-f5w6fw6q 4688 10 structured structured JJ cord-006870-f5w6fw6q 4688 11 QW QW NNP cord-006870-f5w6fw6q 4688 12 helped help VBD cord-006870-f5w6fw6q 4688 13 confirm confirm VB cord-006870-f5w6fw6q 4688 14 SRSE SRSE NNP cord-006870-f5w6fw6q 4688 15 , , , cord-006870-f5w6fw6q 4688 16 facilitating facilitate VBG cord-006870-f5w6fw6q 4688 17 the the DT cord-006870-f5w6fw6q 4688 18 enrollment enrollment NN cord-006870-f5w6fw6q 4688 19 of of IN cord-006870-f5w6fw6q 4688 20 appropriate appropriate JJ cord-006870-f5w6fw6q 4688 21 patients patient NNS cord-006870-f5w6fw6q 4688 22 into into IN cord-006870-f5w6fw6q 4688 23 this this DT cord-006870-f5w6fw6q 4688 24 Phase phase NN cord-006870-f5w6fw6q 4688 25 3 3 CD cord-006870-f5w6fw6q 4688 26 trial trial NN cord-006870-f5w6fw6q 4688 27 in in IN cord-006870-f5w6fw6q 4688 28 a a DT cord-006870-f5w6fw6q 4688 29 rare rare JJ cord-006870-f5w6fw6q 4688 30 , , , cord-006870-f5w6fw6q 4688 31 critically critically RB cord-006870-f5w6fw6q 4688 32 ill ill JJ cord-006870-f5w6fw6q 4688 33 , , , cord-006870-f5w6fw6q 4688 34 and and CC cord-006870-f5w6fw6q 4688 35 dynamic dynamic JJ cord-006870-f5w6fw6q 4688 36 SRSE SRSE NNP cord-006870-f5w6fw6q 4688 37 patient patient JJ cord-006870-f5w6fw6q 4688 38 population population NN cord-006870-f5w6fw6q 4688 39 . . . cord-006870-f5w6fw6q 4689 1 Autoantibodies autoantibody NNS cord-006870-f5w6fw6q 4689 2 to to IN cord-006870-f5w6fw6q 4689 3 the the DT cord-006870-f5w6fw6q 4689 4 65 65 CD cord-006870-f5w6fw6q 4689 5 kDa kDa NNP cord-006870-f5w6fw6q 4689 6 isoform isoform NN cord-006870-f5w6fw6q 4689 7 of of IN cord-006870-f5w6fw6q 4689 8 gulutamic gulutamic NNP cord-006870-f5w6fw6q 4689 9 acid acid NN cord-006870-f5w6fw6q 4689 10 decarboxylase decarboxylase NN cord-006870-f5w6fw6q 4689 11 ( ( -LRB- cord-006870-f5w6fw6q 4689 12 GAD65 GAD65 NNP cord-006870-f5w6fw6q 4689 13 Ab Ab NNP cord-006870-f5w6fw6q 4689 14 ) ) -RRB- cord-006870-f5w6fw6q 4689 15 , , , cord-006870-f5w6fw6q 4689 16 commonly commonly RB cord-006870-f5w6fw6q 4689 17 found find VBN cord-006870-f5w6fw6q 4689 18 in in IN cord-006870-f5w6fw6q 4689 19 T1DM T1DM NNP cord-006870-f5w6fw6q 4689 20 patients patient NNS cord-006870-f5w6fw6q 4689 21 , , , cord-006870-f5w6fw6q 4689 22 have have VBP cord-006870-f5w6fw6q 4689 23 been be VBN cord-006870-f5w6fw6q 4689 24 associated associate VBN cord-006870-f5w6fw6q 4689 25 with with IN cord-006870-f5w6fw6q 4689 26 drug drug NN cord-006870-f5w6fw6q 4689 27 resistant resistant JJ cord-006870-f5w6fw6q 4689 28 epilepsy epilepsy NN cord-006870-f5w6fw6q 4689 29 . . . cord-006870-f5w6fw6q 4690 1 Ketosis ketosis NN cord-006870-f5w6fw6q 4690 2 prone prone JJ cord-006870-f5w6fw6q 4690 3 diabetes diabetes NN cord-006870-f5w6fw6q 4690 4 is be VBZ cord-006870-f5w6fw6q 4690 5 a a DT cord-006870-f5w6fw6q 4690 6 heterogenous heterogenous JJ cord-006870-f5w6fw6q 4690 7 syndrome syndrome NN cord-006870-f5w6fw6q 4690 8 encompassing encompass VBG cord-006870-f5w6fw6q 4690 9 various various JJ cord-006870-f5w6fw6q 4690 10 forms form NNS cord-006870-f5w6fw6q 4690 11 of of IN cord-006870-f5w6fw6q 4690 12 beta beta JJ cord-006870-f5w6fw6q 4690 13 cell cell NN cord-006870-f5w6fw6q 4690 14 dysfunction dysfunction NN cord-006870-f5w6fw6q 4690 15 culminating culminate VBG cord-006870-f5w6fw6q 4690 16 in in IN cord-006870-f5w6fw6q 4690 17 diabetic diabetic JJ cord-006870-f5w6fw6q 4690 18 ketoacidosis ketoacidosis NN cord-006870-f5w6fw6q 4690 19 . . . cord-006870-f5w6fw6q 4691 1 Rates rate NNS cord-006870-f5w6fw6q 4691 2 of of IN cord-006870-f5w6fw6q 4691 3 epilepsy epilepsy NN cord-006870-f5w6fw6q 4691 4 in in IN cord-006870-f5w6fw6q 4691 5 patients patient NNS cord-006870-f5w6fw6q 4691 6 with with IN cord-006870-f5w6fw6q 4691 7 ketosis ketosis JJ cord-006870-f5w6fw6q 4691 8 prone prone JJ cord-006870-f5w6fw6q 4691 9 diabetes diabete NNS cord-006870-f5w6fw6q 4691 10 are be VBP cord-006870-f5w6fw6q 4691 11 not not RB cord-006870-f5w6fw6q 4691 12 known know VBN cord-006870-f5w6fw6q 4691 13 . . . cord-006870-f5w6fw6q 4692 1 We -PRON- PRP cord-006870-f5w6fw6q 4692 2 compared compare VBD cord-006870-f5w6fw6q 4692 3 the the DT cord-006870-f5w6fw6q 4692 4 prevalence prevalence NN cord-006870-f5w6fw6q 4692 5 of of IN cord-006870-f5w6fw6q 4692 6 epilepsy epilepsy NN cord-006870-f5w6fw6q 4692 7 in in IN cord-006870-f5w6fw6q 4692 8 patients patient NNS cord-006870-f5w6fw6q 4692 9 with with IN cord-006870-f5w6fw6q 4692 10 ketosis ketosis JJ cord-006870-f5w6fw6q 4692 11 prone prone JJ cord-006870-f5w6fw6q 4692 12 diabetes diabetes NN cord-006870-f5w6fw6q 4692 13 in in IN cord-006870-f5w6fw6q 4692 14 a a DT cord-006870-f5w6fw6q 4692 15 multi multi JJ cord-006870-f5w6fw6q 4692 16 - - JJ cord-006870-f5w6fw6q 4692 17 ethnic ethnic JJ cord-006870-f5w6fw6q 4692 18 population population NN cord-006870-f5w6fw6q 4692 19 with with IN cord-006870-f5w6fw6q 4692 20 the the DT cord-006870-f5w6fw6q 4692 21 prevalence prevalence NN cord-006870-f5w6fw6q 4692 22 of of IN cord-006870-f5w6fw6q 4692 23 epilepsy epilepsy NN cord-006870-f5w6fw6q 4692 24 in in IN cord-006870-f5w6fw6q 4692 25 the the DT cord-006870-f5w6fw6q 4692 26 type type NN cord-006870-f5w6fw6q 4692 27 1 1 CD cord-006870-f5w6fw6q 4692 28 diabetes diabetes NN cord-006870-f5w6fw6q 4692 29 population population NN cord-006870-f5w6fw6q 4692 30 as as RB cord-006870-f5w6fw6q 4692 31 well well RB cord-006870-f5w6fw6q 4692 32 as as IN cord-006870-f5w6fw6q 4692 33 the the DT cord-006870-f5w6fw6q 4692 34 general general JJ cord-006870-f5w6fw6q 4692 35 population population NN cord-006870-f5w6fw6q 4692 36 in in IN cord-006870-f5w6fw6q 4692 37 a a DT cord-006870-f5w6fw6q 4692 38 metropolitan metropolitan JJ cord-006870-f5w6fw6q 4692 39 medical medical JJ cord-006870-f5w6fw6q 4692 40 center center NN cord-006870-f5w6fw6q 4692 41 . . . cord-006870-f5w6fw6q 4693 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4693 2 study study NN cord-006870-f5w6fw6q 4693 3 design design NN cord-006870-f5w6fw6q 4693 4 is be VBZ cord-006870-f5w6fw6q 4693 5 Prospective prospective JJ cord-006870-f5w6fw6q 4693 6 review review NN cord-006870-f5w6fw6q 4693 7 of of IN cord-006870-f5w6fw6q 4693 8 retrospectively retrospectively RB cord-006870-f5w6fw6q 4693 9 collected collect VBN cord-006870-f5w6fw6q 4693 10 sera sera NNP cord-006870-f5w6fw6q 4693 11 of of IN cord-006870-f5w6fw6q 4693 12 500 500 CD cord-006870-f5w6fw6q 4693 13 patients patient NNS cord-006870-f5w6fw6q 4693 14 admitted admit VBN cord-006870-f5w6fw6q 4693 15 for for IN cord-006870-f5w6fw6q 4693 16 diabetic diabetic JJ cord-006870-f5w6fw6q 4693 17 ketoacidosis ketoacidosis NN cord-006870-f5w6fw6q 4693 18 ( ( -LRB- cord-006870-f5w6fw6q 4693 19 defined define VBN cord-006870-f5w6fw6q 4693 20 as as IN cord-006870-f5w6fw6q 4693 21 pH pH NNP cord-006870-f5w6fw6q 4693 22 < < XX cord-006870-f5w6fw6q 4693 23 7.3 7.3 CD cord-006870-f5w6fw6q 4693 24 , , , cord-006870-f5w6fw6q 4693 25 bicarb bicarb NN cord-006870-f5w6fw6q 4693 26 < < XX cord-006870-f5w6fw6q 4693 27 17 17 CD cord-006870-f5w6fw6q 4693 28 , , , cord-006870-f5w6fw6q 4693 29 with with IN cord-006870-f5w6fw6q 4693 30 ketonemia ketonemia NNP cord-006870-f5w6fw6q 4693 31 or or CC cord-006870-f5w6fw6q 4693 32 ketonuria ketonuria NNP cord-006870-f5w6fw6q 4693 33 ) ) -RRB- cord-006870-f5w6fw6q 4693 34 for for IN cord-006870-f5w6fw6q 4693 35 the the DT cord-006870-f5w6fw6q 4693 36 presence presence NN cord-006870-f5w6fw6q 4693 37 of of IN cord-006870-f5w6fw6q 4693 38 GAD65 GAD65 NNP cord-006870-f5w6fw6q 4693 39 Ab Ab NNP cord-006870-f5w6fw6q 4693 40 . . . cord-006870-f5w6fw6q 4694 1 All all PDT cord-006870-f5w6fw6q 4694 2 these these DT cord-006870-f5w6fw6q 4694 3 sera sera NNP cord-006870-f5w6fw6q 4694 4 were be VBD cord-006870-f5w6fw6q 4694 5 assessed assess VBN cord-006870-f5w6fw6q 4694 6 separately separately RB cord-006870-f5w6fw6q 4694 7 for for IN cord-006870-f5w6fw6q 4694 8 autoantibody autoantibody NNP cord-006870-f5w6fw6q 4694 9 presence presence NN cord-006870-f5w6fw6q 4694 10 or or CC cord-006870-f5w6fw6q 4694 11 absence absence NN cord-006870-f5w6fw6q 4694 12 at at IN cord-006870-f5w6fw6q 4694 13 Dr Dr NNP cord-006870-f5w6fw6q 4694 14 Hampe Hampe NNP cord-006870-f5w6fw6q 4694 15 's 's POS cord-006870-f5w6fw6q 4694 16 lab lab NN cord-006870-f5w6fw6q 4694 17 in in IN cord-006870-f5w6fw6q 4694 18 Washington Washington NNP cord-006870-f5w6fw6q 4694 19 , , , cord-006870-f5w6fw6q 4694 20 Seattle Seattle NNP cord-006870-f5w6fw6q 4694 21 . . . cord-006870-f5w6fw6q 4695 1 We -PRON- PRP cord-006870-f5w6fw6q 4695 2 also also RB cord-006870-f5w6fw6q 4695 3 reviewed review VBD cord-006870-f5w6fw6q 4695 4 patients patient NNS cord-006870-f5w6fw6q 4695 5 medical medical JJ cord-006870-f5w6fw6q 4695 6 records record NNS cord-006870-f5w6fw6q 4695 7 for for IN cord-006870-f5w6fw6q 4695 8 neurological neurological JJ cord-006870-f5w6fw6q 4695 9 diagnoses diagnosis NNS cord-006870-f5w6fw6q 4695 10 . . . cord-006870-f5w6fw6q 4696 1 This this DT cord-006870-f5w6fw6q 4696 2 done do VBN cord-006870-f5w6fw6q 4696 3 in in IN cord-006870-f5w6fw6q 4696 4 a a DT cord-006870-f5w6fw6q 4696 5 blinded blinded JJ cord-006870-f5w6fw6q 4696 6 fashion fashion NN cord-006870-f5w6fw6q 4696 7 by by IN cord-006870-f5w6fw6q 4696 8 two two CD cord-006870-f5w6fw6q 4696 9 separate separate JJ cord-006870-f5w6fw6q 4696 10 reviewers reviewer NNS cord-006870-f5w6fw6q 4696 11 . . . cord-006870-f5w6fw6q 4697 1 Out out IN cord-006870-f5w6fw6q 4697 2 of of IN cord-006870-f5w6fw6q 4697 3 our -PRON- PRP$ cord-006870-f5w6fw6q 4697 4 500 500 CD cord-006870-f5w6fw6q 4697 5 patients patient NNS cord-006870-f5w6fw6q 4697 6 with with IN cord-006870-f5w6fw6q 4697 7 ketosis ketosis JJ cord-006870-f5w6fw6q 4697 8 prone prone JJ cord-006870-f5w6fw6q 4697 9 diabetes diabete NNS cord-006870-f5w6fw6q 4697 10 , , , cord-006870-f5w6fw6q 4697 11 4.3 4.3 CD cord-006870-f5w6fw6q 4697 12 % % NN cord-006870-f5w6fw6q 4697 13 also also RB cord-006870-f5w6fw6q 4697 14 had have VBD cord-006870-f5w6fw6q 4697 15 epilepsy epilepsy NN cord-006870-f5w6fw6q 4697 16 . . . cord-006870-f5w6fw6q 4698 1 This this DT cord-006870-f5w6fw6q 4698 2 is be VBZ cord-006870-f5w6fw6q 4698 3 higher high JJR cord-006870-f5w6fw6q 4698 4 than than IN cord-006870-f5w6fw6q 4698 5 the the DT cord-006870-f5w6fw6q 4698 6 published publish VBN cord-006870-f5w6fw6q 4698 7 rate rate NN cord-006870-f5w6fw6q 4698 8 in in IN cord-006870-f5w6fw6q 4698 9 Type type NN cord-006870-f5w6fw6q 4698 10 1 1 CD cord-006870-f5w6fw6q 4698 11 Diabetics diabetic NNS cord-006870-f5w6fw6q 4698 12 ( ( -LRB- cord-006870-f5w6fw6q 4698 13 1.35 1.35 CD cord-006870-f5w6fw6q 4698 14 % % NN cord-006870-f5w6fw6q 4698 15 ) ) -RRB- cord-006870-f5w6fw6q 4698 16 and and CC cord-006870-f5w6fw6q 4698 17 the the DT cord-006870-f5w6fw6q 4698 18 general general JJ cord-006870-f5w6fw6q 4698 19 population population NN cord-006870-f5w6fw6q 4698 20 in in IN cord-006870-f5w6fw6q 4698 21 the the DT cord-006870-f5w6fw6q 4698 22 surrounding surround VBG cord-006870-f5w6fw6q 4698 23 area area NN cord-006870-f5w6fw6q 4698 24 ( ( -LRB- cord-006870-f5w6fw6q 4698 25 < < NNP cord-006870-f5w6fw6q 4698 26 0.05 0.05 CD cord-006870-f5w6fw6q 4698 27 % % NN cord-006870-f5w6fw6q 4698 28 ) ) -RRB- cord-006870-f5w6fw6q 4698 29 . . . cord-006870-f5w6fw6q 4699 1 Antibody antibody NN cord-006870-f5w6fw6q 4699 2 testing testing NN cord-006870-f5w6fw6q 4699 3 revealed reveal VBD cord-006870-f5w6fw6q 4699 4 21 21 CD cord-006870-f5w6fw6q 4699 5 % % NN cord-006870-f5w6fw6q 4699 6 of of IN cord-006870-f5w6fw6q 4699 7 patients patient NNS cord-006870-f5w6fw6q 4699 8 with with IN cord-006870-f5w6fw6q 4699 9 ketosis ketosis JJ cord-006870-f5w6fw6q 4699 10 prone prone JJ cord-006870-f5w6fw6q 4699 11 diabetes diabete NNS cord-006870-f5w6fw6q 4699 12 were be VBD cord-006870-f5w6fw6q 4699 13 GAD65 GAD65 NNP cord-006870-f5w6fw6q 4699 14 Ab Ab NNP cord-006870-f5w6fw6q 4699 15 positive positive JJ cord-006870-f5w6fw6q 4699 16 with with IN cord-006870-f5w6fw6q 4699 17 a a DT cord-006870-f5w6fw6q 4699 18 rate rate NN cord-006870-f5w6fw6q 4699 19 of of IN cord-006870-f5w6fw6q 4699 20 epilepsy epilepsy NN cord-006870-f5w6fw6q 4699 21 of of IN cord-006870-f5w6fw6q 4699 22 1 1 CD cord-006870-f5w6fw6q 4699 23 % % NN cord-006870-f5w6fw6q 4699 24 . . . cord-006870-f5w6fw6q 4700 1 A a DT cord-006870-f5w6fw6q 4700 2 two two CD cord-006870-f5w6fw6q 4700 3 - - HYPH cord-006870-f5w6fw6q 4700 4 tailed tailed JJ cord-006870-f5w6fw6q 4700 5 T T NNP cord-006870-f5w6fw6q 4700 6 test test NN cord-006870-f5w6fw6q 4700 7 between between IN cord-006870-f5w6fw6q 4700 8 the the DT cord-006870-f5w6fw6q 4700 9 GAD65 GAD65 NNP cord-006870-f5w6fw6q 4700 10 Ab Ab NNP cord-006870-f5w6fw6q 4700 11 + + CC cord-006870-f5w6fw6q 4700 12 group group NN cord-006870-f5w6fw6q 4700 13 and and CC cord-006870-f5w6fw6q 4700 14 GAD65 GAD65 NNP cord-006870-f5w6fw6q 4700 15 AB AB NNP cord-006870-f5w6fw6q 4701 1 -group -group NNP cord-006870-f5w6fw6q 4701 2 showed show VBD cord-006870-f5w6fw6q 4701 3 no no DT cord-006870-f5w6fw6q 4701 4 statistically statistically RB cord-006870-f5w6fw6q 4701 5 significant significant JJ cord-006870-f5w6fw6q 4701 6 difference difference NN cord-006870-f5w6fw6q 4701 7 in in IN cord-006870-f5w6fw6q 4701 8 prevalence prevalence NN cord-006870-f5w6fw6q 4701 9 of of IN cord-006870-f5w6fw6q 4701 10 epilepsy epilepsy NN cord-006870-f5w6fw6q 4701 11 in in IN cord-006870-f5w6fw6q 4701 12 these these DT cord-006870-f5w6fw6q 4701 13 two two CD cord-006870-f5w6fw6q 4701 14 groups group NNS cord-006870-f5w6fw6q 4701 15 . . . cord-006870-f5w6fw6q 4702 1 While while IN cord-006870-f5w6fw6q 4702 2 prevalence prevalence NN cord-006870-f5w6fw6q 4702 3 of of IN cord-006870-f5w6fw6q 4702 4 epilepsy epilepsy NN cord-006870-f5w6fw6q 4702 5 is be VBZ cord-006870-f5w6fw6q 4702 6 higher high JJR cord-006870-f5w6fw6q 4702 7 in in IN cord-006870-f5w6fw6q 4702 8 the the DT cord-006870-f5w6fw6q 4702 9 ketosis ketosis NN cord-006870-f5w6fw6q 4702 10 prone prone JJ cord-006870-f5w6fw6q 4702 11 diabetes diabetes NN cord-006870-f5w6fw6q 4702 12 population population NN cord-006870-f5w6fw6q 4702 13 than than IN cord-006870-f5w6fw6q 4702 14 the the DT cord-006870-f5w6fw6q 4702 15 general general JJ cord-006870-f5w6fw6q 4702 16 population population NN cord-006870-f5w6fw6q 4702 17 of of IN cord-006870-f5w6fw6q 4702 18 Houston Houston NNP cord-006870-f5w6fw6q 4702 19 , , , cord-006870-f5w6fw6q 4702 20 the the DT cord-006870-f5w6fw6q 4702 21 difference difference NN cord-006870-f5w6fw6q 4702 22 is be VBZ cord-006870-f5w6fw6q 4702 23 not not RB cord-006870-f5w6fw6q 4702 24 related relate VBN cord-006870-f5w6fw6q 4702 25 to to IN cord-006870-f5w6fw6q 4702 26 titers titer NNS cord-006870-f5w6fw6q 4702 27 of of IN cord-006870-f5w6fw6q 4702 28 GAD65 GAD65 NNP cord-006870-f5w6fw6q 4702 29 Ab Ab NNP cord-006870-f5w6fw6q 4702 30 , , , cord-006870-f5w6fw6q 4702 31 and and CC cord-006870-f5w6fw6q 4702 32 must must MD cord-006870-f5w6fw6q 4702 33 be be VB cord-006870-f5w6fw6q 4702 34 due due JJ cord-006870-f5w6fw6q 4702 35 to to IN cord-006870-f5w6fw6q 4702 36 some some DT cord-006870-f5w6fw6q 4702 37 other other JJ cord-006870-f5w6fw6q 4702 38 unknown unknown JJ cord-006870-f5w6fw6q 4702 39 factor factor NN cord-006870-f5w6fw6q 4702 40 in in IN cord-006870-f5w6fw6q 4702 41 these these DT cord-006870-f5w6fw6q 4702 42 patients patient NNS cord-006870-f5w6fw6q 4702 43 Management Management NNP cord-006870-f5w6fw6q 4702 44 of of IN cord-006870-f5w6fw6q 4702 45 refractory refractory JJ cord-006870-f5w6fw6q 4702 46 status status NN cord-006870-f5w6fw6q 4702 47 epilepticus epilepticus NN cord-006870-f5w6fw6q 4702 48 commonly commonly RB cord-006870-f5w6fw6q 4702 49 involves involve VBZ cord-006870-f5w6fw6q 4702 50 the the DT cord-006870-f5w6fw6q 4702 51 induction induction NN cord-006870-f5w6fw6q 4702 52 of of IN cord-006870-f5w6fw6q 4702 53 seizure seizure NN cord-006870-f5w6fw6q 4702 54 - - : cord-006870-f5w6fw6q 4702 55 or or CC cord-006870-f5w6fw6q 4702 56 burstsuppression burstsuppression NN cord-006870-f5w6fw6q 4702 57 using use VBG cord-006870-f5w6fw6q 4702 58 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4702 59 agents agent NNS cord-006870-f5w6fw6q 4702 60 . . . cord-006870-f5w6fw6q 4703 1 However however RB cord-006870-f5w6fw6q 4703 2 , , , cord-006870-f5w6fw6q 4703 3 the the DT cord-006870-f5w6fw6q 4703 4 duration duration NN cord-006870-f5w6fw6q 4703 5 and and CC cord-006870-f5w6fw6q 4703 6 endpoints endpoint NNS cord-006870-f5w6fw6q 4703 7 of of IN cord-006870-f5w6fw6q 4703 8 these these DT cord-006870-f5w6fw6q 4703 9 therapies therapy NNS cord-006870-f5w6fw6q 4703 10 are be VBP cord-006870-f5w6fw6q 4703 11 not not RB cord-006870-f5w6fw6q 4703 12 well well RB cord-006870-f5w6fw6q 4703 13 defined define VBN cord-006870-f5w6fw6q 4703 14 . . . cord-006870-f5w6fw6q 4704 1 Specifically specifically RB cord-006870-f5w6fw6q 4704 2 , , , cord-006870-f5w6fw6q 4704 3 weaning wean VBG cord-006870-f5w6fw6q 4704 4 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4704 5 agents agent NNS cord-006870-f5w6fw6q 4704 6 is be VBZ cord-006870-f5w6fw6q 4704 7 complicated complicate VBN cord-006870-f5w6fw6q 4704 8 by by IN cord-006870-f5w6fw6q 4704 9 the the DT cord-006870-f5w6fw6q 4704 10 emergence emergence NN cord-006870-f5w6fw6q 4704 11 of of IN cord-006870-f5w6fw6q 4704 12 EEG EEG NNP cord-006870-f5w6fw6q 4704 13 patterns pattern NNS cord-006870-f5w6fw6q 4704 14 on on IN cord-006870-f5w6fw6q 4704 15 the the DT cord-006870-f5w6fw6q 4704 16 ictal ictal JJ cord-006870-f5w6fw6q 4704 17 - - HYPH cord-006870-f5w6fw6q 4704 18 interictal interictal JJ cord-006870-f5w6fw6q 4704 19 continuum continuum NN cord-006870-f5w6fw6q 4704 20 ( ( -LRB- cord-006870-f5w6fw6q 4704 21 IIC IIC NNP cord-006870-f5w6fw6q 4704 22 ) ) -RRB- cord-006870-f5w6fw6q 4704 23 , , , cord-006870-f5w6fw6q 4704 24 which which WDT cord-006870-f5w6fw6q 4704 25 have have VBP cord-006870-f5w6fw6q 4704 26 uncertain uncertain JJ cord-006870-f5w6fw6q 4704 27 significance significance NN cord-006870-f5w6fw6q 4704 28 , , , cord-006870-f5w6fw6q 4704 29 given give VBN cord-006870-f5w6fw6q 4704 30 that that IN cord-006870-f5w6fw6q 4704 31 IIC IIC NNP cord-006870-f5w6fw6q 4704 32 patterns pattern NNS cord-006870-f5w6fw6q 4704 33 may may MD cord-006870-f5w6fw6q 4704 34 worsen worsen VB cord-006870-f5w6fw6q 4704 35 cerebral cerebral JJ cord-006870-f5w6fw6q 4704 36 metabolism metabolism NN cord-006870-f5w6fw6q 4704 37 and and CC cord-006870-f5w6fw6q 4704 38 oxygenation oxygenation NN cord-006870-f5w6fw6q 4704 39 , , , cord-006870-f5w6fw6q 4704 40 have have VBP cord-006870-f5w6fw6q 4704 41 a a DT cord-006870-f5w6fw6q 4704 42 dissociation dissociation NN cord-006870-f5w6fw6q 4704 43 between between IN cord-006870-f5w6fw6q 4704 44 scalp scalp NN cord-006870-f5w6fw6q 4704 45 and and CC cord-006870-f5w6fw6q 4704 46 depth depth NN cord-006870-f5w6fw6q 4704 47 EEG EEG NNP cord-006870-f5w6fw6q 4704 48 recordings recording NNS cord-006870-f5w6fw6q 4704 49 , , , cord-006870-f5w6fw6q 4704 50 and and CC cord-006870-f5w6fw6q 4704 51 indicate indicate VBP cord-006870-f5w6fw6q 4704 52 a a DT cord-006870-f5w6fw6q 4704 53 late late JJ cord-006870-f5w6fw6q 4704 54 stage stage NN cord-006870-f5w6fw6q 4704 55 of of IN cord-006870-f5w6fw6q 4704 56 status status NN cord-006870-f5w6fw6q 4704 57 epilepticus epilepticus NN cord-006870-f5w6fw6q 4704 58 itself -PRON- PRP cord-006870-f5w6fw6q 4704 59 . . . cord-006870-f5w6fw6q 4705 1 Determining determine VBG cord-006870-f5w6fw6q 4705 2 the the DT cord-006870-f5w6fw6q 4705 3 significance significance NN cord-006870-f5w6fw6q 4705 4 of of IN cord-006870-f5w6fw6q 4705 5 IIC IIC NNP cord-006870-f5w6fw6q 4705 6 patterns pattern NNS cord-006870-f5w6fw6q 4705 7 in in IN cord-006870-f5w6fw6q 4705 8 the the DT cord-006870-f5w6fw6q 4705 9 unique unique JJ cord-006870-f5w6fw6q 4705 10 context context NN cord-006870-f5w6fw6q 4705 11 of of IN cord-006870-f5w6fw6q 4705 12 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4705 13 weaning weaning NN cord-006870-f5w6fw6q 4705 14 is be VBZ cord-006870-f5w6fw6q 4705 15 important important JJ cord-006870-f5w6fw6q 4705 16 to to TO cord-006870-f5w6fw6q 4705 17 prevent prevent VB cord-006870-f5w6fw6q 4705 18 the the DT cord-006870-f5w6fw6q 4705 19 potential potential NN cord-006870-f5w6fw6q 4705 20 for for IN cord-006870-f5w6fw6q 4705 21 unnecessarily unnecessarily RB cord-006870-f5w6fw6q 4705 22 prolonging prolong VBG cord-006870-f5w6fw6q 4705 23 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4705 24 coma coma NN cord-006870-f5w6fw6q 4705 25 . . . cord-006870-f5w6fw6q 4706 1 We -PRON- PRP cord-006870-f5w6fw6q 4706 2 identified identify VBD cord-006870-f5w6fw6q 4706 3 a a DT cord-006870-f5w6fw6q 4706 4 series series NN cord-006870-f5w6fw6q 4706 5 of of IN cord-006870-f5w6fw6q 4706 6 patients patient NNS cord-006870-f5w6fw6q 4706 7 who who WP cord-006870-f5w6fw6q 4706 8 underwent undergo VBD cord-006870-f5w6fw6q 4706 9 over over IN cord-006870-f5w6fw6q 4706 10 48 48 CD cord-006870-f5w6fw6q 4706 11 hours hour NNS cord-006870-f5w6fw6q 4706 12 of of IN cord-006870-f5w6fw6q 4706 13 burst burst NN cord-006870-f5w6fw6q 4706 14 - - HYPH cord-006870-f5w6fw6q 4706 15 suppression suppression NN cord-006870-f5w6fw6q 4706 16 therapy therapy NN cord-006870-f5w6fw6q 4706 17 , , , cord-006870-f5w6fw6q 4706 18 multiple multiple JJ cord-006870-f5w6fw6q 4706 19 weaning weaning NN cord-006870-f5w6fw6q 4706 20 attempts attempt NNS cord-006870-f5w6fw6q 4706 21 , , , cord-006870-f5w6fw6q 4706 22 and and CC cord-006870-f5w6fw6q 4706 23 continued continue VBN cord-006870-f5w6fw6q 4706 24 weaning wean VBG cord-006870-f5w6fw6q 4706 25 despite despite IN cord-006870-f5w6fw6q 4706 26 the the DT cord-006870-f5w6fw6q 4706 27 initial initial JJ cord-006870-f5w6fw6q 4706 28 emergence emergence NN cord-006870-f5w6fw6q 4706 29 of of IN cord-006870-f5w6fw6q 4706 30 IIC IIC NNP cord-006870-f5w6fw6q 4706 31 patterns pattern NNS cord-006870-f5w6fw6q 4706 32 . . . cord-006870-f5w6fw6q 4707 1 Patients patient NNS cord-006870-f5w6fw6q 4707 2 who who WP cord-006870-f5w6fw6q 4707 3 experienced experience VBD cord-006870-f5w6fw6q 4707 4 anoxic anoxic JJ cord-006870-f5w6fw6q 4707 5 brain brain NN cord-006870-f5w6fw6q 4707 6 injury injury NN cord-006870-f5w6fw6q 4707 7 were be VBD cord-006870-f5w6fw6q 4707 8 excluded exclude VBN cord-006870-f5w6fw6q 4707 9 from from IN cord-006870-f5w6fw6q 4707 10 the the DT cord-006870-f5w6fw6q 4707 11 series series NN cord-006870-f5w6fw6q 4707 12 . . . cord-006870-f5w6fw6q 4708 1 We -PRON- PRP cord-006870-f5w6fw6q 4708 2 report report VBP cord-006870-f5w6fw6q 4708 3 5 5 CD cord-006870-f5w6fw6q 4708 4 cases case NNS cord-006870-f5w6fw6q 4708 5 of of IN cord-006870-f5w6fw6q 4708 6 patients patient NNS cord-006870-f5w6fw6q 4708 7 who who WP cord-006870-f5w6fw6q 4708 8 underwent undergo VBD cord-006870-f5w6fw6q 4708 9 successful successful JJ cord-006870-f5w6fw6q 4708 10 weaning weaning NN cord-006870-f5w6fw6q 4708 11 despite despite IN cord-006870-f5w6fw6q 4708 12 initial initial JJ cord-006870-f5w6fw6q 4708 13 emergence emergence NN cord-006870-f5w6fw6q 4708 14 of of IN cord-006870-f5w6fw6q 4708 15 IIC IIC NNP cord-006870-f5w6fw6q 4708 16 patterns pattern NNS cord-006870-f5w6fw6q 4708 17 . . . cord-006870-f5w6fw6q 4709 1 EEG EEG NNP cord-006870-f5w6fw6q 4709 2 patterns pattern NNS cord-006870-f5w6fw6q 4709 3 following follow VBG cord-006870-f5w6fw6q 4709 4 anesthetic anesthetic NN cord-006870-f5w6fw6q 4709 5 weaning weaning NN cord-006870-f5w6fw6q 4709 6 ( ( -LRB- cord-006870-f5w6fw6q 4709 7 including include VBG cord-006870-f5w6fw6q 4709 8 lateralized lateralized JJ cord-006870-f5w6fw6q 4709 9 periodic periodic JJ cord-006870-f5w6fw6q 4709 10 discharges discharge NNS cord-006870-f5w6fw6q 4709 11 approaching approach VBG cord-006870-f5w6fw6q 4709 12 3 3 CD cord-006870-f5w6fw6q 4709 13 Hz Hz NNP cord-006870-f5w6fw6q 4709 14 frequency frequency NN cord-006870-f5w6fw6q 4709 15 and and CC cord-006870-f5w6fw6q 4709 16 lateralized lateralized JJ cord-006870-f5w6fw6q 4709 17 rhythmic rhythmic JJ cord-006870-f5w6fw6q 4709 18 delta delta NN cord-006870-f5w6fw6q 4709 19 activity activity NN cord-006870-f5w6fw6q 4709 20 ) ) -RRB- cord-006870-f5w6fw6q 4709 21 as as RB cord-006870-f5w6fw6q 4709 22 well well RB cord-006870-f5w6fw6q 4709 23 as as IN cord-006870-f5w6fw6q 4709 24 terminal terminal JJ cord-006870-f5w6fw6q 4709 25 EEG EEG NNP cord-006870-f5w6fw6q 4709 26 patterns pattern NNS cord-006870-f5w6fw6q 4709 27 are be VBP cord-006870-f5w6fw6q 4709 28 described describe VBN cord-006870-f5w6fw6q 4709 29 in in IN cord-006870-f5w6fw6q 4709 30 detail detail NN cord-006870-f5w6fw6q 4709 31 . . . cord-006870-f5w6fw6q 4710 1 In in IN cord-006870-f5w6fw6q 4710 2 these these DT cord-006870-f5w6fw6q 4710 3 5 5 CD cord-006870-f5w6fw6q 4710 4 patients patient NNS cord-006870-f5w6fw6q 4710 5 , , , cord-006870-f5w6fw6q 4710 6 continuing continue VBG cord-006870-f5w6fw6q 4710 7 weaning weaning NN cord-006870-f5w6fw6q 4710 8 of of IN cord-006870-f5w6fw6q 4710 9 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4710 10 agents agent NNS cord-006870-f5w6fw6q 4710 11 despite despite IN cord-006870-f5w6fw6q 4710 12 the the DT cord-006870-f5w6fw6q 4710 13 emergence emergence NN cord-006870-f5w6fw6q 4710 14 of of IN cord-006870-f5w6fw6q 4710 15 IIC IIC NNP cord-006870-f5w6fw6q 4710 16 patterns pattern NNS cord-006870-f5w6fw6q 4710 17 did do VBD cord-006870-f5w6fw6q 4710 18 not not RB cord-006870-f5w6fw6q 4710 19 result result VB cord-006870-f5w6fw6q 4710 20 in in IN cord-006870-f5w6fw6q 4710 21 relapse relapse NN cord-006870-f5w6fw6q 4710 22 to to IN cord-006870-f5w6fw6q 4710 23 status status NN cord-006870-f5w6fw6q 4710 24 epilepticus epilepticus NN cord-006870-f5w6fw6q 4710 25 . . . cord-006870-f5w6fw6q 4711 1 While while IN cord-006870-f5w6fw6q 4711 2 the the DT cord-006870-f5w6fw6q 4711 3 metabolic metabolic JJ cord-006870-f5w6fw6q 4711 4 impact impact NN cord-006870-f5w6fw6q 4711 5 of of IN cord-006870-f5w6fw6q 4711 6 these these DT cord-006870-f5w6fw6q 4711 7 patterns pattern NNS cord-006870-f5w6fw6q 4711 8 on on IN cord-006870-f5w6fw6q 4711 9 brain brain NN cord-006870-f5w6fw6q 4711 10 activity activity NN cord-006870-f5w6fw6q 4711 11 is be VBZ cord-006870-f5w6fw6q 4711 12 uncertain uncertain JJ cord-006870-f5w6fw6q 4711 13 , , , cord-006870-f5w6fw6q 4711 14 weaning wean VBG cord-006870-f5w6fw6q 4711 15 strategies strategy NNS cord-006870-f5w6fw6q 4711 16 that that WDT cord-006870-f5w6fw6q 4711 17 treat treat VBP cord-006870-f5w6fw6q 4711 18 IIC IIC NNP cord-006870-f5w6fw6q 4711 19 as as IN cord-006870-f5w6fw6q 4711 20 a a DT cord-006870-f5w6fw6q 4711 21 surrogate surrogate NN cord-006870-f5w6fw6q 4711 22 of of IN cord-006870-f5w6fw6q 4711 23 recurrent recurrent JJ cord-006870-f5w6fw6q 4711 24 status status NN cord-006870-f5w6fw6q 4711 25 epilepticus epilepticus NN cord-006870-f5w6fw6q 4711 26 risk risk NN cord-006870-f5w6fw6q 4711 27 further further RB cord-006870-f5w6fw6q 4711 28 prolonging prolong VBG cord-006870-f5w6fw6q 4711 29 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4711 30 management management NN cord-006870-f5w6fw6q 4711 31 and and CC cord-006870-f5w6fw6q 4711 32 its -PRON- PRP$ cord-006870-f5w6fw6q 4711 33 known know VBN cord-006870-f5w6fw6q 4711 34 toxicity toxicity NN cord-006870-f5w6fw6q 4711 35 . . . cord-006870-f5w6fw6q 4712 1 We -PRON- PRP cord-006870-f5w6fw6q 4712 2 speculate speculate VBP cord-006870-f5w6fw6q 4712 3 that that IN cord-006870-f5w6fw6q 4712 4 IIC IIC NNP cord-006870-f5w6fw6q 4712 5 patterns pattern NNS cord-006870-f5w6fw6q 4712 6 are be VBP cord-006870-f5w6fw6q 4712 7 transitional transitional JJ cord-006870-f5w6fw6q 4712 8 and and CC cord-006870-f5w6fw6q 4712 9 may may MD cord-006870-f5w6fw6q 4712 10 have have VB cord-006870-f5w6fw6q 4712 11 a a DT cord-006870-f5w6fw6q 4712 12 context context NN cord-006870-f5w6fw6q 4712 13 - - HYPH cord-006870-f5w6fw6q 4712 14 specific specific JJ cord-006870-f5w6fw6q 4712 15 association association NN cord-006870-f5w6fw6q 4712 16 with with IN cord-006870-f5w6fw6q 4712 17 status status NN cord-006870-f5w6fw6q 4712 18 epilepticus epilepticus NN cord-006870-f5w6fw6q 4712 19 relapse relapse NN cord-006870-f5w6fw6q 4712 20 , , , cord-006870-f5w6fw6q 4712 21 with with IN cord-006870-f5w6fw6q 4712 22 less less JJR cord-006870-f5w6fw6q 4712 23 risk risk NN cord-006870-f5w6fw6q 4712 24 conferred confer VBN cord-006870-f5w6fw6q 4712 25 when when WRB cord-006870-f5w6fw6q 4712 26 these these DT cord-006870-f5w6fw6q 4712 27 patterns pattern NNS cord-006870-f5w6fw6q 4712 28 are be VBP cord-006870-f5w6fw6q 4712 29 observed observe VBN cord-006870-f5w6fw6q 4712 30 during during IN cord-006870-f5w6fw6q 4712 31 the the DT cord-006870-f5w6fw6q 4712 32 weaning weaning NN cord-006870-f5w6fw6q 4712 33 of of IN cord-006870-f5w6fw6q 4712 34 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4712 35 agents agent NNS cord-006870-f5w6fw6q 4712 36 after after IN cord-006870-f5w6fw6q 4712 37 prolonged prolonged JJ cord-006870-f5w6fw6q 4712 38 burst burst NN cord-006870-f5w6fw6q 4712 39 - - HYPH cord-006870-f5w6fw6q 4712 40 suppression suppression NN cord-006870-f5w6fw6q 4712 41 therapy therapy NN cord-006870-f5w6fw6q 4712 42 . . . cord-006870-f5w6fw6q 4713 1 Other other JJ cord-006870-f5w6fw6q 4713 2 electrographic electrographic JJ cord-006870-f5w6fw6q 4713 3 features feature VBZ cord-006870-f5w6fw6q 4713 4 aside aside RB cord-006870-f5w6fw6q 4713 5 from from IN cord-006870-f5w6fw6q 4713 6 this this DT cord-006870-f5w6fw6q 4713 7 clinical clinical JJ cord-006870-f5w6fw6q 4713 8 context context NN cord-006870-f5w6fw6q 4713 9 may may MD cord-006870-f5w6fw6q 4713 10 discriminate discriminate VB cord-006870-f5w6fw6q 4713 11 the the DT cord-006870-f5w6fw6q 4713 12 risk risk NN cord-006870-f5w6fw6q 4713 13 of of IN cord-006870-f5w6fw6q 4713 14 status status NN cord-006870-f5w6fw6q 4713 15 epilepticus epilepticus NN cord-006870-f5w6fw6q 4713 16 relapse relapse NN cord-006870-f5w6fw6q 4713 17 , , , cord-006870-f5w6fw6q 4713 18 such such JJ cord-006870-f5w6fw6q 4713 19 as as IN cord-006870-f5w6fw6q 4713 20 EEG EEG NNP cord-006870-f5w6fw6q 4713 21 background background NN cord-006870-f5w6fw6q 4713 22 activity activity NN cord-006870-f5w6fw6q 4713 23 . . . cord-006870-f5w6fw6q 4714 1 Brivaracetam Brivaracetam NNP cord-006870-f5w6fw6q 4714 2 ( ( -LRB- cord-006870-f5w6fw6q 4714 3 BRV BRV NNP cord-006870-f5w6fw6q 4714 4 ) ) -RRB- cord-006870-f5w6fw6q 4714 5 is be VBZ cord-006870-f5w6fw6q 4714 6 approved approve VBN cord-006870-f5w6fw6q 4714 7 as as IN cord-006870-f5w6fw6q 4714 8 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4714 9 therapy therapy NN cord-006870-f5w6fw6q 4714 10 for for IN cord-006870-f5w6fw6q 4714 11 focal focal JJ cord-006870-f5w6fw6q 4714 12 ( ( -LRB- cord-006870-f5w6fw6q 4714 13 partialyears partialyear NNS cord-006870-f5w6fw6q 4714 14 ) ) -RRB- cord-006870-f5w6fw6q 4714 15 with with IN cord-006870-f5w6fw6q 4714 16 epilepsy epilepsy NN cord-006870-f5w6fw6q 4714 17 . . . cord-006870-f5w6fw6q 4715 1 BRV BRV NNP cord-006870-f5w6fw6q 4715 2 is be VBZ cord-006870-f5w6fw6q 4715 3 available available JJ cord-006870-f5w6fw6q 4715 4 as as IN cord-006870-f5w6fw6q 4715 5 oral oral JJ cord-006870-f5w6fw6q 4715 6 tablets tablet NNS cord-006870-f5w6fw6q 4715 7 , , , cord-006870-f5w6fw6q 4715 8 oral oral JJ cord-006870-f5w6fw6q 4715 9 solution solution NN cord-006870-f5w6fw6q 4715 10 , , , cord-006870-f5w6fw6q 4715 11 and and CC cord-006870-f5w6fw6q 4715 12 an an DT cord-006870-f5w6fw6q 4715 13 intravenous intravenous JJ cord-006870-f5w6fw6q 4715 14 ( ( -LRB- cord-006870-f5w6fw6q 4715 15 IV IV NNP cord-006870-f5w6fw6q 4715 16 ) ) -RRB- cord-006870-f5w6fw6q 4715 17 formulation formulation NN cord-006870-f5w6fw6q 4715 18 . . . cord-006870-f5w6fw6q 4716 1 The the DT cord-006870-f5w6fw6q 4716 2 formulations formulation NNS cord-006870-f5w6fw6q 4716 3 are be VBP cord-006870-f5w6fw6q 4716 4 interchangeable interchangeable JJ cord-006870-f5w6fw6q 4716 5 . . . cord-006870-f5w6fw6q 4717 1 This this DT cord-006870-f5w6fw6q 4717 2 abstract abstract JJ cord-006870-f5w6fw6q 4717 3 reports report VBZ cord-006870-f5w6fw6q 4717 4 the the DT cord-006870-f5w6fw6q 4717 5 safety safety NN cord-006870-f5w6fw6q 4717 6 and and CC cord-006870-f5w6fw6q 4717 7 tolerability tolerability NN cord-006870-f5w6fw6q 4717 8 of of IN cord-006870-f5w6fw6q 4717 9 IV IV NNP cord-006870-f5w6fw6q 4717 10 BRV BRV NNP cord-006870-f5w6fw6q 4717 11 . . . cord-006870-f5w6fw6q 4718 1 During during IN cord-006870-f5w6fw6q 4718 2 clinical clinical JJ cord-006870-f5w6fw6q 4718 3 development development NN cord-006870-f5w6fw6q 4718 4 , , , cord-006870-f5w6fw6q 4718 5 177 177 CD cord-006870-f5w6fw6q 4718 6 participants participant NNS cord-006870-f5w6fw6q 4718 7 received receive VBD cord-006870-f5w6fw6q 4718 8 IV IV NNP cord-006870-f5w6fw6q 4718 9 BRV BRV NNP cord-006870-f5w6fw6q 4718 10 . . . cord-006870-f5w6fw6q 4719 1 We -PRON- PRP cord-006870-f5w6fw6q 4719 2 report report VBP cord-006870-f5w6fw6q 4719 3 pooled pool VBD cord-006870-f5w6fw6q 4719 4 safety safety NN cord-006870-f5w6fw6q 4719 5 findings finding NNS cord-006870-f5w6fw6q 4719 6 from from IN cord-006870-f5w6fw6q 4719 7 153 153 CD cord-006870-f5w6fw6q 4719 8 participants participant NNS cord-006870-f5w6fw6q 4719 9 receiving receive VBG cord-006870-f5w6fw6q 4719 10 BRV BRV NNP cord-006870-f5w6fw6q 4719 11 25 25 CD cord-006870-f5w6fw6q 4719 12 - - SYM cord-006870-f5w6fw6q 4719 13 150 150 CD cord-006870-f5w6fw6q 4719 14 mg mg NNP cord-006870-f5w6fw6q 4719 15 doses dose NNS cord-006870-f5w6fw6q 4719 16 . . . cord-006870-f5w6fw6q 4720 1 The the DT cord-006870-f5w6fw6q 4720 2 therapeutic therapeutic JJ cord-006870-f5w6fw6q 4720 3 range range NN cord-006870-f5w6fw6q 4720 4 of of IN cord-006870-f5w6fw6q 4720 5 BRV BRV NNP cord-006870-f5w6fw6q 4720 6 is be VBZ cord-006870-f5w6fw6q 4720 7 25 25 CD cord-006870-f5w6fw6q 4720 8 - - SYM cord-006870-f5w6fw6q 4720 9 100 100 CD cord-006870-f5w6fw6q 4720 10 mg mg NNS cord-006870-f5w6fw6q 4720 11 twice twice RB cord-006870-f5w6fw6q 4720 12 daily daily RB cord-006870-f5w6fw6q 4720 13 . . . cord-006870-f5w6fw6q 4721 1 In in IN cord-006870-f5w6fw6q 4721 2 N01256 N01256 NNP cord-006870-f5w6fw6q 4721 3 , , , cord-006870-f5w6fw6q 4721 4 24 24 CD cord-006870-f5w6fw6q 4721 5 healthy healthy JJ cord-006870-f5w6fw6q 4721 6 volunteers volunteer NNS cord-006870-f5w6fw6q 4721 7 received receive VBD cord-006870-f5w6fw6q 4721 8 IV IV NNP cord-006870-f5w6fw6q 4721 9 BRV BRV NNP cord-006870-f5w6fw6q 4721 10 as as IN cord-006870-f5w6fw6q 4721 11 a a DT cord-006870-f5w6fw6q 4721 12 15-minute 15-minute JJ cord-006870-f5w6fw6q 4721 13 infusion infusion NN cord-006870-f5w6fw6q 4721 14 or or CC cord-006870-f5w6fw6q 4721 15 50 50 CD cord-006870-f5w6fw6q 4721 16 mg mg NNP cord-006870-f5w6fw6q 4721 17 / / SYM cord-006870-f5w6fw6q 4721 18 min min NNP cord-006870-f5w6fw6q 4721 19 bolus bolus NN cord-006870-f5w6fw6q 4721 20 ( ( -LRB- cord-006870-f5w6fw6q 4721 21 25 25 CD cord-006870-f5w6fw6q 4721 22 , , , cord-006870-f5w6fw6q 4721 23 50 50 CD cord-006870-f5w6fw6q 4721 24 , , , cord-006870-f5w6fw6q 4721 25 100 100 CD cord-006870-f5w6fw6q 4721 26 , , , cord-006870-f5w6fw6q 4721 27 or or CC cord-006870-f5w6fw6q 4721 28 150 150 CD cord-006870-f5w6fw6q 4721 29 mg mg NNS cord-006870-f5w6fw6q 4721 30 single single JJ cord-006870-f5w6fw6q 4721 31 doses dose NNS cord-006870-f5w6fw6q 4721 32 ; ; : cord-006870-f5w6fw6q 4721 33 n=6 n=6 JJ cord-006870-f5w6fw6q 4721 34 in in IN cord-006870-f5w6fw6q 4721 35 all all DT cord-006870-f5w6fw6q 4721 36 groups group NNS cord-006870-f5w6fw6q 4721 37 ) ) -RRB- cord-006870-f5w6fw6q 4721 38 . . . cord-006870-f5w6fw6q 4722 1 In in IN cord-006870-f5w6fw6q 4722 2 EP0007 ep0007 NN cord-006870-f5w6fw6q 4722 3 ( ( -LRB- cord-006870-f5w6fw6q 4722 4 NCT01796899 NCT01796899 NNP cord-006870-f5w6fw6q 4722 5 ) ) -RRB- cord-006870-f5w6fw6q 4722 6 , , , cord-006870-f5w6fw6q 4722 7 25 25 CD cord-006870-f5w6fw6q 4722 8 healthy healthy JJ cord-006870-f5w6fw6q 4722 9 volunteers volunteer NNS cord-006870-f5w6fw6q 4722 10 received receive VBD cord-006870-f5w6fw6q 4722 11 IV IV NNP cord-006870-f5w6fw6q 4722 12 BRV BRV NNP cord-006870-f5w6fw6q 4722 13 100 100 CD cord-006870-f5w6fw6q 4722 14 mg mg NNS cord-006870-f5w6fw6q 4722 15 as as IN cord-006870-f5w6fw6q 4722 16 a a DT cord-006870-f5w6fw6q 4722 17 single single JJ cord-006870-f5w6fw6q 4722 18 2-minute 2-minute CD cord-006870-f5w6fw6q 4722 19 bolus bolus NN cord-006870-f5w6fw6q 4722 20 injection injection NN cord-006870-f5w6fw6q 4722 21 or or CC cord-006870-f5w6fw6q 4722 22 oral oral JJ cord-006870-f5w6fw6q 4722 23 tablets tablet NNS cord-006870-f5w6fw6q 4722 24 . . . cord-006870-f5w6fw6q 4723 1 In in IN cord-006870-f5w6fw6q 4723 2 N01258 N01258 NNP cord-006870-f5w6fw6q 4723 3 ( ( -LRB- cord-006870-f5w6fw6q 4723 4 NCT01405508 NCT01405508 NNP cord-006870-f5w6fw6q 4723 5 ) ) -RRB- cord-006870-f5w6fw6q 4723 6 , , , cord-006870-f5w6fw6q 4723 7 104 104 CD cord-006870-f5w6fw6q 4723 8 patients patient NNS cord-006870-f5w6fw6q 4723 9 received receive VBD cord-006870-f5w6fw6q 4723 10 7 7 CD cord-006870-f5w6fw6q 4723 11 days day NNS cord-006870-f5w6fw6q 4723 12 of of IN cord-006870-f5w6fw6q 4723 13 BRV BRV NNP cord-006870-f5w6fw6q 4723 14 oral oral JJ cord-006870-f5w6fw6q 4723 15 tablets tablet NNS cord-006870-f5w6fw6q 4723 16 100 100 CD cord-006870-f5w6fw6q 4723 17 mg mg NNS cord-006870-f5w6fw6q 4723 18 twice twice RB cord-006870-f5w6fw6q 4723 19 daily daily JJ cord-006870-f5w6fw6q 4723 20 or or CC cord-006870-f5w6fw6q 4723 21 placebo placebo NN cord-006870-f5w6fw6q 4723 22 , , , cord-006870-f5w6fw6q 4723 23 and and CC cord-006870-f5w6fw6q 4723 24 then then RB cord-006870-f5w6fw6q 4723 25 4.5 4.5 CD cord-006870-f5w6fw6q 4723 26 days day NNS cord-006870-f5w6fw6q 4723 27 of of IN cord-006870-f5w6fw6q 4723 28 IV IV NNP cord-006870-f5w6fw6q 4723 29 BRV BRV NNP cord-006870-f5w6fw6q 4723 30 100 100 CD cord-006870-f5w6fw6q 4723 31 mg mg NNS cord-006870-f5w6fw6q 4723 32 twice twice RB cord-006870-f5w6fw6q 4723 33 daily daily RB cord-006870-f5w6fw6q 4723 34 either either CC cord-006870-f5w6fw6q 4723 35 as as IN cord-006870-f5w6fw6q 4723 36 a a DT cord-006870-f5w6fw6q 4723 37 2-minute 2-minute CD cord-006870-f5w6fw6q 4723 38 bolus bolus NN cord-006870-f5w6fw6q 4723 39 or or CC cord-006870-f5w6fw6q 4723 40 15-minute 15-minute JJ cord-006870-f5w6fw6q 4723 41 infusion infusion NN cord-006870-f5w6fw6q 4723 42 for for IN cord-006870-f5w6fw6q 4723 43 nine nine CD cord-006870-f5w6fw6q 4723 44 doses dose NNS cord-006870-f5w6fw6q 4723 45 in in IN cord-006870-f5w6fw6q 4723 46 total total NN cord-006870-f5w6fw6q 4723 47 . . . cord-006870-f5w6fw6q 4724 1 Treatment treatment NN cord-006870-f5w6fw6q 4724 2 - - HYPH cord-006870-f5w6fw6q 4724 3 emergent emergent JJ cord-006870-f5w6fw6q 4724 4 adverse adverse JJ cord-006870-f5w6fw6q 4724 5 event event NN cord-006870-f5w6fw6q 4725 1 ( ( -LRB- cord-006870-f5w6fw6q 4725 2 TEAE TEAE NNP cord-006870-f5w6fw6q 4725 3 ) ) -RRB- cord-006870-f5w6fw6q 4725 4 data datum NNS cord-006870-f5w6fw6q 4725 5 were be VBD cord-006870-f5w6fw6q 4725 6 pooled pool VBN cord-006870-f5w6fw6q 4725 7 . . . cord-006870-f5w6fw6q 4726 1 Data datum NNS cord-006870-f5w6fw6q 4726 2 reported report VBN cord-006870-f5w6fw6q 4726 3 are be VBP cord-006870-f5w6fw6q 4726 4 for for IN cord-006870-f5w6fw6q 4726 5 IV IV NNP cord-006870-f5w6fw6q 4727 1 BRV BRV NNP cord-006870-f5w6fw6q 4727 2 25 25 CD cord-006870-f5w6fw6q 4727 3 - - SYM cord-006870-f5w6fw6q 4727 4 150 150 CD cord-006870-f5w6fw6q 4727 5 mg mg NN cord-006870-f5w6fw6q 4727 6 ( ( -LRB- cord-006870-f5w6fw6q 4727 7 n=153 n=153 NNP cord-006870-f5w6fw6q 4727 8 ) ) -RRB- cord-006870-f5w6fw6q 4727 9 . . . cord-006870-f5w6fw6q 4728 1 Most Most JJS cord-006870-f5w6fw6q 4728 2 frequent frequent JJ cord-006870-f5w6fw6q 4728 3 TEAEs teae NNS cord-006870-f5w6fw6q 4728 4 were be VBD cord-006870-f5w6fw6q 4728 5 somnolence somnolence NN cord-006870-f5w6fw6q 4728 6 30.1 30.1 CD cord-006870-f5w6fw6q 4728 7 % % NN cord-006870-f5w6fw6q 4728 8 , , , cord-006870-f5w6fw6q 4728 9 dizziness dizziness NN cord-006870-f5w6fw6q 4728 10 15.7 15.7 CD cord-006870-f5w6fw6q 4728 11 % % NN cord-006870-f5w6fw6q 4728 12 , , , cord-006870-f5w6fw6q 4728 13 fatigue fatigue NN cord-006870-f5w6fw6q 4728 14 15.0 15.0 CD cord-006870-f5w6fw6q 4728 15 % % NN cord-006870-f5w6fw6q 4728 16 , , , cord-006870-f5w6fw6q 4728 17 headache headache NN cord-006870-f5w6fw6q 4728 18 7.2 7.2 CD cord-006870-f5w6fw6q 4728 19 % % NN cord-006870-f5w6fw6q 4728 20 , , , cord-006870-f5w6fw6q 4728 21 dysgeusia dysgeusia NNP cord-006870-f5w6fw6q 4728 22 6.5 6.5 CD cord-006870-f5w6fw6q 4728 23 % % NN cord-006870-f5w6fw6q 4728 24 , , , cord-006870-f5w6fw6q 4728 25 euphoric euphoric JJ cord-006870-f5w6fw6q 4728 26 mood mood NN cord-006870-f5w6fw6q 4728 27 3.9 3.9 CD cord-006870-f5w6fw6q 4728 28 % % NN cord-006870-f5w6fw6q 4728 29 , , , cord-006870-f5w6fw6q 4728 30 feeling feel VBG cord-006870-f5w6fw6q 4728 31 drunk drunk JJ cord-006870-f5w6fw6q 4728 32 3.9 3.9 CD cord-006870-f5w6fw6q 4728 33 % % NN cord-006870-f5w6fw6q 4728 34 , , , cord-006870-f5w6fw6q 4728 35 and and CC cord-006870-f5w6fw6q 4728 36 infusion infusion NN cord-006870-f5w6fw6q 4728 37 - - HYPH cord-006870-f5w6fw6q 4728 38 site site NN cord-006870-f5w6fw6q 4728 39 pain pain NN cord-006870-f5w6fw6q 4728 40 3.3 3.3 CD cord-006870-f5w6fw6q 4728 41 % % NN cord-006870-f5w6fw6q 4728 42 . . . cord-006870-f5w6fw6q 4729 1 Infusion infusion NN cord-006870-f5w6fw6q 4729 2 - - HYPH cord-006870-f5w6fw6q 4729 3 site site NN cord-006870-f5w6fw6q 4729 4 pain pain NN cord-006870-f5w6fw6q 4729 5 was be VBD cord-006870-f5w6fw6q 4729 6 specific specific JJ cord-006870-f5w6fw6q 4729 7 to to IN cord-006870-f5w6fw6q 4729 8 administration administration NN cord-006870-f5w6fw6q 4729 9 route route NN cord-006870-f5w6fw6q 4729 10 . . . cord-006870-f5w6fw6q 4730 1 Most Most JJS cord-006870-f5w6fw6q 4730 2 TEAEs teae NNS cord-006870-f5w6fw6q 4730 3 were be VBD cord-006870-f5w6fw6q 4730 4 mild mild JJ cord-006870-f5w6fw6q 4730 5 or or CC cord-006870-f5w6fw6q 4730 6 moderate moderate JJ cord-006870-f5w6fw6q 4730 7 and and CC cord-006870-f5w6fw6q 4730 8 occurred occur VBD cord-006870-f5w6fw6q 4730 9 mostly mostly RB cord-006870-f5w6fw6q 4730 10 in in IN cord-006870-f5w6fw6q 4730 11 healthy healthy JJ cord-006870-f5w6fw6q 4730 12 volunteers volunteer NNS cord-006870-f5w6fw6q 4730 13 . . . cord-006870-f5w6fw6q 4731 1 IV IV NNP cord-006870-f5w6fw6q 4731 2 BRV BRV NNP cord-006870-f5w6fw6q 4731 3 was be VBD cord-006870-f5w6fw6q 4731 4 well well RB cord-006870-f5w6fw6q 4731 5 tolerated tolerate VBN cord-006870-f5w6fw6q 4731 6 , , , cord-006870-f5w6fw6q 4731 7 with with IN cord-006870-f5w6fw6q 4731 8 an an DT cord-006870-f5w6fw6q 4731 9 AE AE NNP cord-006870-f5w6fw6q 4731 10 profile profile NN cord-006870-f5w6fw6q 4731 11 consistent consistent JJ cord-006870-f5w6fw6q 4731 12 with with IN cord-006870-f5w6fw6q 4731 13 oral oral JJ cord-006870-f5w6fw6q 4731 14 administration administration NN cord-006870-f5w6fw6q 4731 15 except except IN cord-006870-f5w6fw6q 4731 16 for for IN cord-006870-f5w6fw6q 4731 17 routespecific routespecific NNP cord-006870-f5w6fw6q 4731 18 injection injection NN cord-006870-f5w6fw6q 4731 19 - - HYPH cord-006870-f5w6fw6q 4731 20 site site NN cord-006870-f5w6fw6q 4731 21 AEs AEs NNP cord-006870-f5w6fw6q 4731 22 , , , cord-006870-f5w6fw6q 4731 23 dysgeusia dysgeusia NNP cord-006870-f5w6fw6q 4731 24 , , , cord-006870-f5w6fw6q 4731 25 euphoric euphoric JJ cord-006870-f5w6fw6q 4731 26 mood mood NN cord-006870-f5w6fw6q 4731 27 and and CC cord-006870-f5w6fw6q 4731 28 feeling feel VBG cord-006870-f5w6fw6q 4731 29 drunk drunk JJ cord-006870-f5w6fw6q 4731 30 . . . cord-006870-f5w6fw6q 4732 1 The the DT cord-006870-f5w6fw6q 4732 2 interpretation interpretation NN cord-006870-f5w6fw6q 4732 3 of of IN cord-006870-f5w6fw6q 4732 4 these these DT cord-006870-f5w6fw6q 4732 5 data datum NNS cord-006870-f5w6fw6q 4732 6 was be VBD cord-006870-f5w6fw6q 4732 7 complicated complicate VBN cord-006870-f5w6fw6q 4732 8 by by IN cord-006870-f5w6fw6q 4732 9 the the DT cord-006870-f5w6fw6q 4732 10 difficulty difficulty NN cord-006870-f5w6fw6q 4732 11 of of IN cord-006870-f5w6fw6q 4732 12 pooling pool VBG cord-006870-f5w6fw6q 4732 13 disparate disparate JJ cord-006870-f5w6fw6q 4732 14 studies study NNS cord-006870-f5w6fw6q 4732 15 involving involve VBG cord-006870-f5w6fw6q 4732 16 healthy healthy JJ cord-006870-f5w6fw6q 4732 17 volunteers volunteer NNS cord-006870-f5w6fw6q 4732 18 and and CC cord-006870-f5w6fw6q 4732 19 epilepsy epilepsy NN cord-006870-f5w6fw6q 4732 20 patients patient NNS cord-006870-f5w6fw6q 4732 21 with with IN cord-006870-f5w6fw6q 4732 22 heterogeneous heterogeneous JJ cord-006870-f5w6fw6q 4732 23 medical medical JJ cord-006870-f5w6fw6q 4732 24 histories history NNS cord-006870-f5w6fw6q 4732 25 and and CC cord-006870-f5w6fw6q 4732 26 concomitant concomitant JJ cord-006870-f5w6fw6q 4732 27 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 4732 28 drug drug NN cord-006870-f5w6fw6q 4732 29 use use NN cord-006870-f5w6fw6q 4732 30 . . . cord-006870-f5w6fw6q 4733 1 Further further JJ cord-006870-f5w6fw6q 4733 2 clinical clinical JJ cord-006870-f5w6fw6q 4733 3 trials trial NNS cord-006870-f5w6fw6q 4733 4 or or CC cord-006870-f5w6fw6q 4733 5 real real JJ cord-006870-f5w6fw6q 4733 6 - - HYPH cord-006870-f5w6fw6q 4733 7 world world NN cord-006870-f5w6fw6q 4733 8 experience experience NN cord-006870-f5w6fw6q 4733 9 are be VBP cord-006870-f5w6fw6q 4733 10 needed need VBN cord-006870-f5w6fw6q 4733 11 to to TO cord-006870-f5w6fw6q 4733 12 understand understand VB cord-006870-f5w6fw6q 4733 13 potential potential JJ cord-006870-f5w6fw6q 4733 14 clinical clinical JJ cord-006870-f5w6fw6q 4733 15 impact impact NN cord-006870-f5w6fw6q 4733 16 . . . cord-006870-f5w6fw6q 4734 1 UCB UCB NNP cord-006870-f5w6fw6q 4734 2 Pharma Pharma NNP cord-006870-f5w6fw6q 4734 3 funded fund VBD cord-006870-f5w6fw6q 4734 4 Refractory refractory JJ cord-006870-f5w6fw6q 4734 5 status status NN cord-006870-f5w6fw6q 4734 6 epilepticus epilepticus NN cord-006870-f5w6fw6q 4734 7 ( ( -LRB- cord-006870-f5w6fw6q 4734 8 RSE RSE NNP cord-006870-f5w6fw6q 4734 9 ) ) -RRB- cord-006870-f5w6fw6q 4734 10 is be VBZ cord-006870-f5w6fw6q 4734 11 a a DT cord-006870-f5w6fw6q 4734 12 challenging challenging JJ cord-006870-f5w6fw6q 4734 13 condition condition NN cord-006870-f5w6fw6q 4734 14 that that WDT cord-006870-f5w6fw6q 4734 15 requires require VBZ cord-006870-f5w6fw6q 4734 16 multiple multiple JJ cord-006870-f5w6fw6q 4734 17 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 4734 18 drugs drug NNS cord-006870-f5w6fw6q 4734 19 ( ( -LRB- cord-006870-f5w6fw6q 4734 20 AED AED NNP cord-006870-f5w6fw6q 4734 21 ) ) -RRB- cord-006870-f5w6fw6q 4734 22 to to TO cord-006870-f5w6fw6q 4734 23 treat treat VB cord-006870-f5w6fw6q 4734 24 . . . cord-006870-f5w6fw6q 4735 1 During during IN cord-006870-f5w6fw6q 4735 2 RSE RSE NNP cord-006870-f5w6fw6q 4735 3 , , , cord-006870-f5w6fw6q 4735 4 the the DT cord-006870-f5w6fw6q 4735 5 brain brain NN cord-006870-f5w6fw6q 4735 6 is be VBZ cord-006870-f5w6fw6q 4735 7 under under IN cord-006870-f5w6fw6q 4735 8 excessive excessive JJ cord-006870-f5w6fw6q 4735 9 excitation excitation NN cord-006870-f5w6fw6q 4735 10 , , , cord-006870-f5w6fw6q 4735 11 which which WDT cord-006870-f5w6fw6q 4735 12 results result VBZ cord-006870-f5w6fw6q 4735 13 in in IN cord-006870-f5w6fw6q 4735 14 an an DT cord-006870-f5w6fw6q 4735 15 increase increase NN cord-006870-f5w6fw6q 4735 16 in in IN cord-006870-f5w6fw6q 4735 17 glutamate glutamate NN cord-006870-f5w6fw6q 4735 18 receptors receptor NNS cord-006870-f5w6fw6q 4735 19 such such JJ cord-006870-f5w6fw6q 4735 20 as as IN cord-006870-f5w6fw6q 4735 21 alpha alpha NN cord-006870-f5w6fw6q 4735 22 - - HYPH cord-006870-f5w6fw6q 4735 23 amino-3-hydroxy-5-methyl-4-isoxazolepropionic amino-3-hydroxy-5-methyl-4-isoxazolepropionic JJ cord-006870-f5w6fw6q 4735 24 acid acid NN cord-006870-f5w6fw6q 4735 25 ( ( -LRB- cord-006870-f5w6fw6q 4735 26 AMPA AMPA NNP cord-006870-f5w6fw6q 4735 27 ) ) -RRB- cord-006870-f5w6fw6q 4735 28 and and CC cord-006870-f5w6fw6q 4735 29 Nmethyl Nmethyl NNP cord-006870-f5w6fw6q 4735 30 - - HYPH cord-006870-f5w6fw6q 4735 31 Daspartate Daspartate NNP cord-006870-f5w6fw6q 4735 32 ( ( -LRB- cord-006870-f5w6fw6q 4735 33 NMDA NMDA NNP cord-006870-f5w6fw6q 4735 34 ) ) -RRB- cord-006870-f5w6fw6q 4735 35 .. .. . cord-006870-f5w6fw6q 4736 1 Perampanel Perampanel NNP cord-006870-f5w6fw6q 4736 2 ( ( -LRB- cord-006870-f5w6fw6q 4736 3 PER per NN cord-006870-f5w6fw6q 4736 4 ) ) -RRB- cord-006870-f5w6fw6q 4736 5 , , , cord-006870-f5w6fw6q 4736 6 a a DT cord-006870-f5w6fw6q 4736 7 novel novel NN cord-006870-f5w6fw6q 4736 8 , , , cord-006870-f5w6fw6q 4736 9 noncompetitive noncompetitive JJ cord-006870-f5w6fw6q 4736 10 AMPA AMPA NNP cord-006870-f5w6fw6q 4736 11 - - HYPH cord-006870-f5w6fw6q 4736 12 receptor receptor NN cord-006870-f5w6fw6q 4736 13 antagonist antagonist NN cord-006870-f5w6fw6q 4736 14 , , , cord-006870-f5w6fw6q 4736 15 may may MD cord-006870-f5w6fw6q 4736 16 have have VB cord-006870-f5w6fw6q 4736 17 a a DT cord-006870-f5w6fw6q 4736 18 role role NN cord-006870-f5w6fw6q 4736 19 in in IN cord-006870-f5w6fw6q 4736 20 the the DT cord-006870-f5w6fw6q 4736 21 treatment treatment NN cord-006870-f5w6fw6q 4736 22 of of IN cord-006870-f5w6fw6q 4736 23 RSE rse NN cord-006870-f5w6fw6q 4736 24 and and CC cord-006870-f5w6fw6q 4736 25 there there EX cord-006870-f5w6fw6q 4736 26 are be VBP cord-006870-f5w6fw6q 4736 27 positive positive JJ cord-006870-f5w6fw6q 4736 28 results result NNS cord-006870-f5w6fw6q 4736 29 in in IN cord-006870-f5w6fw6q 4736 30 different different JJ cord-006870-f5w6fw6q 4736 31 animal animal NN cord-006870-f5w6fw6q 4736 32 models model NNS cord-006870-f5w6fw6q 4736 33 with with IN cord-006870-f5w6fw6q 4736 34 RSE RSE NNP cord-006870-f5w6fw6q 4736 35 . . . cord-006870-f5w6fw6q 4737 1 We -PRON- PRP cord-006870-f5w6fw6q 4737 2 identified identify VBD cord-006870-f5w6fw6q 4737 3 8 8 CD cord-006870-f5w6fw6q 4737 4 adults adult NNS cord-006870-f5w6fw6q 4737 5 patients patient NNS cord-006870-f5w6fw6q 4737 6 over over IN cord-006870-f5w6fw6q 4737 7 a a DT cord-006870-f5w6fw6q 4737 8 6 6 CD cord-006870-f5w6fw6q 4737 9 month month NN cord-006870-f5w6fw6q 4737 10 period period NN cord-006870-f5w6fw6q 4737 11 who who WP cord-006870-f5w6fw6q 4737 12 were be VBD cord-006870-f5w6fw6q 4737 13 treated treat VBN cord-006870-f5w6fw6q 4737 14 with with IN cord-006870-f5w6fw6q 4737 15 PER per NN cord-006870-f5w6fw6q 4737 16 for for IN cord-006870-f5w6fw6q 4737 17 different different JJ cord-006870-f5w6fw6q 4737 18 forms form NNS cord-006870-f5w6fw6q 4737 19 of of IN cord-006870-f5w6fw6q 4737 20 RSE rse NN cord-006870-f5w6fw6q 4737 21 . . . cord-006870-f5w6fw6q 4738 1 One one CD cord-006870-f5w6fw6q 4738 2 was be VBD cord-006870-f5w6fw6q 4738 3 excluded exclude VBN cord-006870-f5w6fw6q 4738 4 as as IN cord-006870-f5w6fw6q 4738 5 the the DT cord-006870-f5w6fw6q 4738 6 etiology etiology NN cord-006870-f5w6fw6q 4738 7 of of IN cord-006870-f5w6fw6q 4738 8 RSE RSE NNP cord-006870-f5w6fw6q 4738 9 was be VBD cord-006870-f5w6fw6q 4738 10 anoxic anoxic JJ cord-006870-f5w6fw6q 4738 11 brain brain NN cord-006870-f5w6fw6q 4738 12 injury injury NN cord-006870-f5w6fw6q 4738 13 and and CC cord-006870-f5w6fw6q 4738 14 care care NN cord-006870-f5w6fw6q 4738 15 was be VBD cord-006870-f5w6fw6q 4738 16 transitioned transition VBN cord-006870-f5w6fw6q 4738 17 to to TO cord-006870-f5w6fw6q 4738 18 comfort comfort VB cord-006870-f5w6fw6q 4738 19 only only RB cord-006870-f5w6fw6q 4738 20 within within IN cord-006870-f5w6fw6q 4738 21 24 24 CD cord-006870-f5w6fw6q 4738 22 hours hour NNS cord-006870-f5w6fw6q 4738 23 of of IN cord-006870-f5w6fw6q 4738 24 initiating initiate VBG cord-006870-f5w6fw6q 4738 25 PER per NN cord-006870-f5w6fw6q 4738 26 . . . cord-006870-f5w6fw6q 4739 1 Three three CD cord-006870-f5w6fw6q 4739 2 patients patient NNS cord-006870-f5w6fw6q 4739 3 had have VBD cord-006870-f5w6fw6q 4739 4 a a DT cord-006870-f5w6fw6q 4739 5 definite definite JJ cord-006870-f5w6fw6q 4739 6 response response NN cord-006870-f5w6fw6q 4739 7 to to IN cord-006870-f5w6fw6q 4739 8 PER per NN cord-006870-f5w6fw6q 4739 9 , , , cord-006870-f5w6fw6q 4739 10 which which WDT cord-006870-f5w6fw6q 4739 11 we -PRON- PRP cord-006870-f5w6fw6q 4739 12 defined define VBD cord-006870-f5w6fw6q 4739 13 as as IN cord-006870-f5w6fw6q 4739 14 resolution resolution NN cord-006870-f5w6fw6q 4739 15 of of IN cord-006870-f5w6fw6q 4739 16 ictal ictal JJ cord-006870-f5w6fw6q 4739 17 patterns pattern NNS cord-006870-f5w6fw6q 4739 18 on on IN cord-006870-f5w6fw6q 4739 19 electroencephalogram electroencephalogram FW cord-006870-f5w6fw6q 4739 20 ( ( -LRB- cord-006870-f5w6fw6q 4739 21 EEG EEG NNP cord-006870-f5w6fw6q 4739 22 ) ) -RRB- cord-006870-f5w6fw6q 4739 23 within within IN cord-006870-f5w6fw6q 4739 24 48 48 CD cord-006870-f5w6fw6q 4739 25 hours hour NNS cord-006870-f5w6fw6q 4739 26 of of IN cord-006870-f5w6fw6q 4739 27 PER per NN cord-006870-f5w6fw6q 4739 28 without without IN cord-006870-f5w6fw6q 4739 29 adding add VBG cord-006870-f5w6fw6q 4739 30 a a DT cord-006870-f5w6fw6q 4739 31 new new JJ cord-006870-f5w6fw6q 4739 32 AED AED NNP cord-006870-f5w6fw6q 4739 33 . . . cord-006870-f5w6fw6q 4740 1 One one PRP cord-006870-f5w6fw6q 4740 2 had have VBD cord-006870-f5w6fw6q 4740 3 a a DT cord-006870-f5w6fw6q 4740 4 possible possible JJ cord-006870-f5w6fw6q 4740 5 response response NN cord-006870-f5w6fw6q 4740 6 with with IN cord-006870-f5w6fw6q 4740 7 significant significant JJ cord-006870-f5w6fw6q 4740 8 improvement improvement NN cord-006870-f5w6fw6q 4740 9 in in IN cord-006870-f5w6fw6q 4740 10 EEG EEG NNP cord-006870-f5w6fw6q 4740 11 findings finding NNS cord-006870-f5w6fw6q 4740 12 ; ; : cord-006870-f5w6fw6q 4740 13 however however RB cord-006870-f5w6fw6q 4740 14 , , , cord-006870-f5w6fw6q 4740 15 there there EX cord-006870-f5w6fw6q 4740 16 was be VBD cord-006870-f5w6fw6q 4740 17 some some DT cord-006870-f5w6fw6q 4740 18 EEG EEG NNP cord-006870-f5w6fw6q 4740 19 improvement improvement NN cord-006870-f5w6fw6q 4740 20 predating predate VBG cord-006870-f5w6fw6q 4740 21 the the DT cord-006870-f5w6fw6q 4740 22 initiation initiation NN cord-006870-f5w6fw6q 4740 23 of of IN cord-006870-f5w6fw6q 4740 24 PER per NN cord-006870-f5w6fw6q 4740 25 . . . cord-006870-f5w6fw6q 4741 1 In in IN cord-006870-f5w6fw6q 4741 2 observed observed JJ cord-006870-f5w6fw6q 4741 3 several several JJ cord-006870-f5w6fw6q 4741 4 treatment treatment NN cord-006870-f5w6fw6q 4741 5 factors factor NNS cord-006870-f5w6fw6q 4741 6 that that WDT cord-006870-f5w6fw6q 4741 7 may may MD cord-006870-f5w6fw6q 4741 8 have have VB cord-006870-f5w6fw6q 4741 9 increased increase VBN cord-006870-f5w6fw6q 4741 10 response response NN cord-006870-f5w6fw6q 4741 11 to to IN cord-006870-f5w6fw6q 4741 12 PER per NN cord-006870-f5w6fw6q 4741 13 . . . cord-006870-f5w6fw6q 4742 1 Those those DT cord-006870-f5w6fw6q 4742 2 who who WP cord-006870-f5w6fw6q 4742 3 responded respond VBD cord-006870-f5w6fw6q 4742 4 had have VBD cord-006870-f5w6fw6q 4742 5 it -PRON- PRP cord-006870-f5w6fw6q 4742 6 used use VBN cord-006870-f5w6fw6q 4742 7 earlier early RBR cord-006870-f5w6fw6q 4742 8 in in IN cord-006870-f5w6fw6q 4742 9 the the DT cord-006870-f5w6fw6q 4742 10 treatment treatment NN cord-006870-f5w6fw6q 4742 11 cascade cascade NN cord-006870-f5w6fw6q 4742 12 ( ( -LRB- cord-006870-f5w6fw6q 4742 13 sixth sixth JJ cord-006870-f5w6fw6q 4742 14 or or CC cord-006870-f5w6fw6q 4742 15 seventh seventh JJ cord-006870-f5w6fw6q 4742 16 vs. vs. FW cord-006870-f5w6fw6q 4742 17 ninth ninth JJ cord-006870-f5w6fw6q 4742 18 or or CC cord-006870-f5w6fw6q 4742 19 tenthAED tenthaed XX cord-006870-f5w6fw6q 4742 20 ) ) -RRB- cord-006870-f5w6fw6q 4742 21 , , , cord-006870-f5w6fw6q 4742 22 higher high JJR cord-006870-f5w6fw6q 4742 23 initial initial JJ cord-006870-f5w6fw6q 4742 24 dose dose NN cord-006870-f5w6fw6q 4742 25 ( ( -LRB- cord-006870-f5w6fw6q 4742 26 8 8 CD cord-006870-f5w6fw6q 4742 27 mg mg NN cord-006870-f5w6fw6q 4742 28 vs vs IN cord-006870-f5w6fw6q 4742 29 4 4 CD cord-006870-f5w6fw6q 4742 30 mg mg NNP cord-006870-f5w6fw6q 4742 31 ) ) -RRB- cord-006870-f5w6fw6q 4742 32 , , , cord-006870-f5w6fw6q 4742 33 and and CC cord-006870-f5w6fw6q 4742 34 were be VBD cord-006870-f5w6fw6q 4742 35 escalated escalate VBN cord-006870-f5w6fw6q 4742 36 to to TO cord-006870-f5w6fw6q 4742 37 maximum maximum VB cord-006870-f5w6fw6q 4742 38 dosage dosage NN cord-006870-f5w6fw6q 4742 39 within within IN cord-006870-f5w6fw6q 4742 40 48 48 CD cord-006870-f5w6fw6q 4742 41 hours hour NNS cord-006870-f5w6fw6q 4742 42 . . . cord-006870-f5w6fw6q 4743 1 They -PRON- PRP cord-006870-f5w6fw6q 4743 2 were be VBD cord-006870-f5w6fw6q 4743 3 also also RB cord-006870-f5w6fw6q 4743 4 more more RBR cord-006870-f5w6fw6q 4743 5 likely likely JJ cord-006870-f5w6fw6q 4743 6 be be VB cord-006870-f5w6fw6q 4743 7 receiving receive VBG cord-006870-f5w6fw6q 4743 8 continuous continuous JJ cord-006870-f5w6fw6q 4743 9 ketamine ketamine NN cord-006870-f5w6fw6q 4743 10 and and CC cord-006870-f5w6fw6q 4743 11 midazolam midazolam NN cord-006870-f5w6fw6q 4743 12 , , , cord-006870-f5w6fw6q 4743 13 suggesting suggest VBG cord-006870-f5w6fw6q 4743 14 a a DT cord-006870-f5w6fw6q 4743 15 possible possible JJ cord-006870-f5w6fw6q 4743 16 synergy synergy NN cord-006870-f5w6fw6q 4743 17 with with IN cord-006870-f5w6fw6q 4743 18 PER per NN cord-006870-f5w6fw6q 4743 19 . . . cord-006870-f5w6fw6q 4744 1 There there EX cord-006870-f5w6fw6q 4744 2 were be VBD cord-006870-f5w6fw6q 4744 3 no no DT cord-006870-f5w6fw6q 4744 4 documented document VBN cord-006870-f5w6fw6q 4744 5 adverse adverse JJ cord-006870-f5w6fw6q 4744 6 effects effect NNS cord-006870-f5w6fw6q 4744 7 in in IN cord-006870-f5w6fw6q 4744 8 any any DT cord-006870-f5w6fw6q 4744 9 patient patient NN cord-006870-f5w6fw6q 4744 10 prior prior RB cord-006870-f5w6fw6q 4744 11 to to IN cord-006870-f5w6fw6q 4744 12 discharge discharge NN cord-006870-f5w6fw6q 4744 13 . . . cord-006870-f5w6fw6q 4745 1 One one CD cord-006870-f5w6fw6q 4745 2 patient patient NN cord-006870-f5w6fw6q 4745 3 did do VBD cord-006870-f5w6fw6q 4745 4 experience experience VB cord-006870-f5w6fw6q 4745 5 a a DT cord-006870-f5w6fw6q 4745 6 decline decline NN cord-006870-f5w6fw6q 4745 7 in in IN cord-006870-f5w6fw6q 4745 8 phenytoin phenytoin JJ cord-006870-f5w6fw6q 4745 9 levels level NNS cord-006870-f5w6fw6q 4745 10 , , , cord-006870-f5w6fw6q 4745 11 which which WDT cord-006870-f5w6fw6q 4745 12 could could MD cord-006870-f5w6fw6q 4745 13 be be VB cord-006870-f5w6fw6q 4745 14 related relate VBN cord-006870-f5w6fw6q 4745 15 to to IN cord-006870-f5w6fw6q 4745 16 PER per NN cord-006870-f5w6fw6q 4745 17 as as IN cord-006870-f5w6fw6q 4745 18 there there EX cord-006870-f5w6fw6q 4745 19 are be VBP cord-006870-f5w6fw6q 4745 20 reports report NNS cord-006870-f5w6fw6q 4745 21 of of IN cord-006870-f5w6fw6q 4745 22 enzyme enzyme NN cord-006870-f5w6fw6q 4745 23 - - HYPH cord-006870-f5w6fw6q 4745 24 inducing induce VBG cord-006870-f5w6fw6q 4745 25 properties property NNS cord-006870-f5w6fw6q 4745 26 . . . cord-006870-f5w6fw6q 4746 1 We -PRON- PRP cord-006870-f5w6fw6q 4746 2 observed observe VBD cord-006870-f5w6fw6q 4746 3 efficacy efficacy NN cord-006870-f5w6fw6q 4746 4 of of IN cord-006870-f5w6fw6q 4746 5 PER per NN cord-006870-f5w6fw6q 4746 6 in in IN cord-006870-f5w6fw6q 4746 7 several several JJ cord-006870-f5w6fw6q 4746 8 patients patient NNS cord-006870-f5w6fw6q 4746 9 with with IN cord-006870-f5w6fw6q 4746 10 focal focal JJ cord-006870-f5w6fw6q 4746 11 and and CC cord-006870-f5w6fw6q 4746 12 generalized generalized JJ cord-006870-f5w6fw6q 4746 13 RSE rse NN cord-006870-f5w6fw6q 4746 14 without without IN cord-006870-f5w6fw6q 4746 15 a a DT cord-006870-f5w6fw6q 4746 16 significant significant JJ cord-006870-f5w6fw6q 4746 17 adverse adverse JJ cord-006870-f5w6fw6q 4746 18 effect effect NN cord-006870-f5w6fw6q 4746 19 profile profile NN cord-006870-f5w6fw6q 4746 20 . . . cord-006870-f5w6fw6q 4747 1 Further further JJ cord-006870-f5w6fw6q 4747 2 studies study NNS cord-006870-f5w6fw6q 4747 3 are be VBP cord-006870-f5w6fw6q 4747 4 needed need VBN cord-006870-f5w6fw6q 4747 5 to to TO cord-006870-f5w6fw6q 4747 6 clarify clarify VB cord-006870-f5w6fw6q 4747 7 the the DT cord-006870-f5w6fw6q 4747 8 dosing dosing NN cord-006870-f5w6fw6q 4747 9 , , , cord-006870-f5w6fw6q 4747 10 timing timing NN cord-006870-f5w6fw6q 4747 11 and and CC cord-006870-f5w6fw6q 4747 12 appropriate appropriate JJ cord-006870-f5w6fw6q 4747 13 indications indication NNS cord-006870-f5w6fw6q 4747 14 in in IN cord-006870-f5w6fw6q 4747 15 RSE rse NN cord-006870-f5w6fw6q 4747 16 treatment treatment NN cord-006870-f5w6fw6q 4747 17 . . . cord-006870-f5w6fw6q 4748 1 Topiramate Topiramate NNP cord-006870-f5w6fw6q 4748 2 is be VBZ cord-006870-f5w6fw6q 4748 3 a a DT cord-006870-f5w6fw6q 4748 4 potent potent JJ cord-006870-f5w6fw6q 4748 5 broad broad JJ cord-006870-f5w6fw6q 4748 6 - - HYPH cord-006870-f5w6fw6q 4748 7 spectrum spectrum NN cord-006870-f5w6fw6q 4748 8 anti anti JJ cord-006870-f5w6fw6q 4748 9 - - JJ cord-006870-f5w6fw6q 4748 10 epileptic epileptic JJ cord-006870-f5w6fw6q 4748 11 drug drug NN cord-006870-f5w6fw6q 4748 12 ( ( -LRB- cord-006870-f5w6fw6q 4748 13 AED AED NNP cord-006870-f5w6fw6q 4748 14 ) ) -RRB- cord-006870-f5w6fw6q 4748 15 with with IN cord-006870-f5w6fw6q 4748 16 several several JJ cord-006870-f5w6fw6q 4748 17 mechanisms mechanism NNS cord-006870-f5w6fw6q 4748 18 of of IN cord-006870-f5w6fw6q 4748 19 action action NN cord-006870-f5w6fw6q 4748 20 including include VBG cord-006870-f5w6fw6q 4748 21 blockage blockage NN cord-006870-f5w6fw6q 4748 22 of of IN cord-006870-f5w6fw6q 4748 23 the the DT cord-006870-f5w6fw6q 4748 24 inotropic inotropic NNP cord-006870-f5w6fw6q 4748 25 glutamatergic glutamatergic NNP cord-006870-f5w6fw6q 4748 26 AMPA AMPA NNP cord-006870-f5w6fw6q 4748 27 receptor receptor NN cord-006870-f5w6fw6q 4748 28 , , , cord-006870-f5w6fw6q 4748 29 voltage voltage NN cord-006870-f5w6fw6q 4748 30 - - HYPH cord-006870-f5w6fw6q 4748 31 gated gate VBN cord-006870-f5w6fw6q 4748 32 sodium sodium NN cord-006870-f5w6fw6q 4748 33 channels channel NNS cord-006870-f5w6fw6q 4748 34 , , , cord-006870-f5w6fw6q 4748 35 antagonism antagonism NN cord-006870-f5w6fw6q 4748 36 of of IN cord-006870-f5w6fw6q 4748 37 non non JJ cord-006870-f5w6fw6q 4748 38 - - JJ cord-006870-f5w6fw6q 4748 39 NMDA nmda JJ cord-006870-f5w6fw6q 4748 40 glutamate glutamate NN cord-006870-f5w6fw6q 4748 41 receptors receptor NNS cord-006870-f5w6fw6q 4748 42 and and CC cord-006870-f5w6fw6q 4748 43 enhancement enhancement NN cord-006870-f5w6fw6q 4748 44 of of IN cord-006870-f5w6fw6q 4748 45 GABA GABA NNP cord-006870-f5w6fw6q 4748 46 mediated mediate VBD cord-006870-f5w6fw6q 4748 47 chloride chloride NN cord-006870-f5w6fw6q 4748 48 conductance conductance NN cord-006870-f5w6fw6q 4748 49 . . . cord-006870-f5w6fw6q 4749 1 We -PRON- PRP cord-006870-f5w6fw6q 4749 2 hypothesize hypothesize VBP cord-006870-f5w6fw6q 4749 3 that that IN cord-006870-f5w6fw6q 4749 4 Topiramate Topiramate NNP cord-006870-f5w6fw6q 4749 5 is be VBZ cord-006870-f5w6fw6q 4749 6 an an DT cord-006870-f5w6fw6q 4749 7 effective effective JJ cord-006870-f5w6fw6q 4749 8 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4749 9 therapy therapy NN cord-006870-f5w6fw6q 4749 10 in in IN cord-006870-f5w6fw6q 4749 11 RSE RSE NNP cord-006870-f5w6fw6q 4749 12 and and CC cord-006870-f5w6fw6q 4749 13 SRSE SRSE NNP cord-006870-f5w6fw6q 4749 14 due due IN cord-006870-f5w6fw6q 4749 15 to to IN cord-006870-f5w6fw6q 4749 16 multiple multiple JJ cord-006870-f5w6fw6q 4749 17 mechanisms mechanism NNS cord-006870-f5w6fw6q 4749 18 of of IN cord-006870-f5w6fw6q 4749 19 action action NN cord-006870-f5w6fw6q 4749 20 . . . cord-006870-f5w6fw6q 4750 1 We -PRON- PRP cord-006870-f5w6fw6q 4750 2 performed perform VBD cord-006870-f5w6fw6q 4750 3 a a DT cord-006870-f5w6fw6q 4750 4 retrospective retrospective JJ cord-006870-f5w6fw6q 4750 5 analysis analysis NN cord-006870-f5w6fw6q 4750 6 of of IN cord-006870-f5w6fw6q 4750 7 11 11 CD cord-006870-f5w6fw6q 4750 8 patients patient NNS cord-006870-f5w6fw6q 4750 9 admitted admit VBN cord-006870-f5w6fw6q 4750 10 to to IN cord-006870-f5w6fw6q 4750 11 the the DT cord-006870-f5w6fw6q 4750 12 intensive intensive JJ cord-006870-f5w6fw6q 4750 13 care care NN cord-006870-f5w6fw6q 4750 14 unit unit NN cord-006870-f5w6fw6q 4750 15 with with IN cord-006870-f5w6fw6q 4750 16 status status NN cord-006870-f5w6fw6q 4750 17 epilepticus epilepticus NN cord-006870-f5w6fw6q 4750 18 ( ( -LRB- cord-006870-f5w6fw6q 4750 19 SE SE NNP cord-006870-f5w6fw6q 4750 20 ) ) -RRB- cord-006870-f5w6fw6q 4750 21 at at IN cord-006870-f5w6fw6q 4750 22 a a DT cord-006870-f5w6fw6q 4750 23 tertiary tertiary JJ cord-006870-f5w6fw6q 4750 24 referral referral NN cord-006870-f5w6fw6q 4750 25 center center NN cord-006870-f5w6fw6q 4750 26 from from IN cord-006870-f5w6fw6q 4750 27 2013 2013 CD cord-006870-f5w6fw6q 4750 28 - - SYM cord-006870-f5w6fw6q 4750 29 2016 2016 CD cord-006870-f5w6fw6q 4750 30 . . . cord-006870-f5w6fw6q 4751 1 We -PRON- PRP cord-006870-f5w6fw6q 4751 2 reviewed review VBD cord-006870-f5w6fw6q 4751 3 demographics demographic NNS cord-006870-f5w6fw6q 4751 4 , , , cord-006870-f5w6fw6q 4751 5 age age NN cord-006870-f5w6fw6q 4751 6 , , , cord-006870-f5w6fw6q 4751 7 seizure seizure NN cord-006870-f5w6fw6q 4751 8 type type NN cord-006870-f5w6fw6q 4751 9 , , , cord-006870-f5w6fw6q 4751 10 etiology etiology NN cord-006870-f5w6fw6q 4751 11 , , , cord-006870-f5w6fw6q 4751 12 prior prior JJ cord-006870-f5w6fw6q 4751 13 AED AED NNP cord-006870-f5w6fw6q 4751 14 / / , cord-006870-f5w6fw6q 4751 15 Topiramate Topiramate NNP cord-006870-f5w6fw6q 4751 16 exposure exposure NN cord-006870-f5w6fw6q 4751 17 , , , cord-006870-f5w6fw6q 4751 18 time time NN cord-006870-f5w6fw6q 4751 19 to to TO cord-006870-f5w6fw6q 4751 20 response response NN cord-006870-f5w6fw6q 4751 21 to to IN cord-006870-f5w6fw6q 4751 22 treatment treatment NN cord-006870-f5w6fw6q 4751 23 , , , cord-006870-f5w6fw6q 4751 24 EEG EEG NNP cord-006870-f5w6fw6q 4751 25 reports report VBZ cord-006870-f5w6fw6q 4751 26 and and CC cord-006870-f5w6fw6q 4751 27 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 4751 28 results result NNS cord-006870-f5w6fw6q 4751 29 . . . cord-006870-f5w6fw6q 4752 1 RSE RSE NNP cord-006870-f5w6fw6q 4752 2 was be VBD cord-006870-f5w6fw6q 4752 3 defined define VBN cord-006870-f5w6fw6q 4752 4 as as IN cord-006870-f5w6fw6q 4752 5 failure failure NN cord-006870-f5w6fw6q 4752 6 of of IN cord-006870-f5w6fw6q 4752 7 benzodiazepine benzodiazepine NN cord-006870-f5w6fw6q 4752 8 and and CC cord-006870-f5w6fw6q 4752 9 another another DT cord-006870-f5w6fw6q 4752 10 conventional conventional JJ cord-006870-f5w6fw6q 4752 11 second second JJ cord-006870-f5w6fw6q 4752 12 line line NN cord-006870-f5w6fw6q 4752 13 AED AED NNP cord-006870-f5w6fw6q 4752 14 to to TO cord-006870-f5w6fw6q 4752 15 stop stop VB cord-006870-f5w6fw6q 4752 16 SE SE NNP cord-006870-f5w6fw6q 4752 17 . . . cord-006870-f5w6fw6q 4753 1 SRSE SRSE NNP cord-006870-f5w6fw6q 4753 2 was be VBD cord-006870-f5w6fw6q 4753 3 defined define VBN cord-006870-f5w6fw6q 4753 4 as as IN cord-006870-f5w6fw6q 4753 5 SE SE NNP cord-006870-f5w6fw6q 4753 6 that that WDT cord-006870-f5w6fw6q 4753 7 continues continue VBZ cord-006870-f5w6fw6q 4753 8 or or CC cord-006870-f5w6fw6q 4753 9 recurs recur VBZ cord-006870-f5w6fw6q 4753 10 24 24 CD cord-006870-f5w6fw6q 4753 11 hours hour NNS cord-006870-f5w6fw6q 4753 12 after after IN cord-006870-f5w6fw6q 4753 13 being be VBG cord-006870-f5w6fw6q 4753 14 treated treat VBN cord-006870-f5w6fw6q 4753 15 with with IN cord-006870-f5w6fw6q 4753 16 an an DT cord-006870-f5w6fw6q 4753 17 anesthetic anesthetic JJ cord-006870-f5w6fw6q 4753 18 agent agent NN cord-006870-f5w6fw6q 4753 19 . . . cord-006870-f5w6fw6q 4754 1 6 6 LS cord-006870-f5w6fw6q 4754 2 ( ( -LRB- cord-006870-f5w6fw6q 4754 3 55 55 CD cord-006870-f5w6fw6q 4754 4 % % NN cord-006870-f5w6fw6q 4754 5 ) ) -RRB- cord-006870-f5w6fw6q 4754 6 were be VBD cord-006870-f5w6fw6q 4754 7 male male JJ cord-006870-f5w6fw6q 4754 8 , , , cord-006870-f5w6fw6q 4754 9 6 6 CD cord-006870-f5w6fw6q 4754 10 ( ( -LRB- cord-006870-f5w6fw6q 4754 11 55 55 CD cord-006870-f5w6fw6q 4754 12 % % NN cord-006870-f5w6fw6q 4754 13 ) ) -RRB- cord-006870-f5w6fw6q 4754 14 had have VBD cord-006870-f5w6fw6q 4754 15 a a DT cord-006870-f5w6fw6q 4754 16 history history NN cord-006870-f5w6fw6q 4754 17 of of IN cord-006870-f5w6fw6q 4754 18 seizures seizure NNS cord-006870-f5w6fw6q 4754 19 ; ; : cord-006870-f5w6fw6q 4754 20 mean mean VB cord-006870-f5w6fw6q 4754 21 age age NN cord-006870-f5w6fw6q 4754 22 of of IN cord-006870-f5w6fw6q 4754 23 patients patient NNS cord-006870-f5w6fw6q 4754 24 with with IN cord-006870-f5w6fw6q 4754 25 SE SE NNP cord-006870-f5w6fw6q 4754 26 was be VBD cord-006870-f5w6fw6q 4754 27 62.5 62.5 CD cord-006870-f5w6fw6q 4754 28 years year NNS cord-006870-f5w6fw6q 4754 29 . . . cord-006870-f5w6fw6q 4755 1 Of of IN cord-006870-f5w6fw6q 4755 2 11 11 CD cord-006870-f5w6fw6q 4755 3 treated treat VBN cord-006870-f5w6fw6q 4755 4 patients patient NNS cord-006870-f5w6fw6q 4755 5 , , , cord-006870-f5w6fw6q 4755 6 6 6 CD cord-006870-f5w6fw6q 4755 7 ( ( -LRB- cord-006870-f5w6fw6q 4755 8 55 55 CD cord-006870-f5w6fw6q 4755 9 % % NN cord-006870-f5w6fw6q 4755 10 ) ) -RRB- cord-006870-f5w6fw6q 4755 11 had have VBD cord-006870-f5w6fw6q 4755 12 focal focal JJ cord-006870-f5w6fw6q 4755 13 non non JJ cord-006870-f5w6fw6q 4755 14 - - JJ cord-006870-f5w6fw6q 4755 15 convulsive convulsive JJ cord-006870-f5w6fw6q 4755 16 SE se NN cord-006870-f5w6fw6q 4755 17 ( ( -LRB- cord-006870-f5w6fw6q 4755 18 NCSE NCSE NNP cord-006870-f5w6fw6q 4755 19 ) ) -RRB- cord-006870-f5w6fw6q 4755 20 , , , cord-006870-f5w6fw6q 4755 21 1 1 CD cord-006870-f5w6fw6q 4755 22 ( ( -LRB- cord-006870-f5w6fw6q 4755 23 9 9 CD cord-006870-f5w6fw6q 4755 24 % % NN cord-006870-f5w6fw6q 4755 25 ) ) -RRB- cord-006870-f5w6fw6q 4755 26 had have VBD cord-006870-f5w6fw6q 4755 27 myoclonic myoclonic JJ cord-006870-f5w6fw6q 4755 28 SE SE NNP cord-006870-f5w6fw6q 4755 29 , , , cord-006870-f5w6fw6q 4755 30 1 1 CD cord-006870-f5w6fw6q 4755 31 had have VBD cord-006870-f5w6fw6q 4755 32 myoclonic myoclonic JJ cord-006870-f5w6fw6q 4755 33 , , , cord-006870-f5w6fw6q 4755 34 followed follow VBN cord-006870-f5w6fw6q 4755 35 by by IN cord-006870-f5w6fw6q 4755 36 generalized generalized JJ cord-006870-f5w6fw6q 4755 37 NCSE,1 ncse,1 NN cord-006870-f5w6fw6q 4755 38 ( ( -LRB- cord-006870-f5w6fw6q 4755 39 9 9 CD cord-006870-f5w6fw6q 4755 40 % % NN cord-006870-f5w6fw6q 4755 41 ) ) -RRB- cord-006870-f5w6fw6q 4755 42 had have VBD cord-006870-f5w6fw6q 4755 43 generalized generalize VBN cord-006870-f5w6fw6q 4755 44 NCSE NCSE NNP cord-006870-f5w6fw6q 4755 45 , , , cord-006870-f5w6fw6q 4755 46 and and CC cord-006870-f5w6fw6q 4755 47 1 1 CD cord-006870-f5w6fw6q 4755 48 ( ( -LRB- cord-006870-f5w6fw6q 4755 49 9 9 CD cord-006870-f5w6fw6q 4755 50 % % NN cord-006870-f5w6fw6q 4755 51 ) ) -RRB- cord-006870-f5w6fw6q 4755 52 had have VBD cord-006870-f5w6fw6q 4755 53 focal focal JJ cord-006870-f5w6fw6q 4755 54 and and CC cord-006870-f5w6fw6q 4755 55 generalized generalized JJ cord-006870-f5w6fw6q 4755 56 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 4755 57 SE SE NNP cord-006870-f5w6fw6q 4755 58 , , , cord-006870-f5w6fw6q 4755 59 prior prior RB cord-006870-f5w6fw6q 4755 60 to to IN cord-006870-f5w6fw6q 4755 61 administration administration NN cord-006870-f5w6fw6q 4755 62 of of IN cord-006870-f5w6fw6q 4755 63 Topiramate Topiramate NNP cord-006870-f5w6fw6q 4755 64 . . . cord-006870-f5w6fw6q 4756 1 3 3 LS cord-006870-f5w6fw6q 4756 2 ( ( -LRB- cord-006870-f5w6fw6q 4756 3 27 27 CD cord-006870-f5w6fw6q 4756 4 % % NN cord-006870-f5w6fw6q 4756 5 ) ) -RRB- cord-006870-f5w6fw6q 4756 6 patients patient NNS cord-006870-f5w6fw6q 4756 7 were be VBD cord-006870-f5w6fw6q 4756 8 treated treat VBN cord-006870-f5w6fw6q 4756 9 with with IN cord-006870-f5w6fw6q 4756 10 2 2 CD cord-006870-f5w6fw6q 4756 11 AEDs aed NNS cord-006870-f5w6fw6q 4756 12 , , , cord-006870-f5w6fw6q 4756 13 8 8 CD cord-006870-f5w6fw6q 4756 14 ( ( -LRB- cord-006870-f5w6fw6q 4756 15 72 72 CD cord-006870-f5w6fw6q 4756 16 % % NN cord-006870-f5w6fw6q 4756 17 ) ) -RRB- cord-006870-f5w6fw6q 4756 18 patients patient NNS cord-006870-f5w6fw6q 4756 19 with with IN cord-006870-f5w6fw6q 4756 20 3 3 CD cord-006870-f5w6fw6q 4756 21 AEDs aed NNS cord-006870-f5w6fw6q 4756 22 prior prior RB cord-006870-f5w6fw6q 4756 23 to to IN cord-006870-f5w6fw6q 4756 24 Topiramate Topiramate NNP cord-006870-f5w6fw6q 4756 25 . . . cord-006870-f5w6fw6q 4757 1 Electrographic Electrographic NNP cord-006870-f5w6fw6q 4757 2 seizures seizure NNS cord-006870-f5w6fw6q 4757 3 improved improve VBD cord-006870-f5w6fw6q 4757 4 in in IN cord-006870-f5w6fw6q 4757 5 10 10 CD cord-006870-f5w6fw6q 4757 6 ( ( -LRB- cord-006870-f5w6fw6q 4757 7 91 91 CD cord-006870-f5w6fw6q 4757 8 % % NN cord-006870-f5w6fw6q 4757 9 ) ) -RRB- cord-006870-f5w6fw6q 4757 10 patients patient NNS cord-006870-f5w6fw6q 4757 11 after after IN cord-006870-f5w6fw6q 4757 12 receiving receive VBG cord-006870-f5w6fw6q 4757 13 Topiramate Topiramate NNP cord-006870-f5w6fw6q 4757 14 . . . cord-006870-f5w6fw6q 4758 1 Resolution resolution NN cord-006870-f5w6fw6q 4758 2 of of IN cord-006870-f5w6fw6q 4758 3 electrographic electrographic JJ cord-006870-f5w6fw6q 4758 4 seizures seizure NNS cord-006870-f5w6fw6q 4758 5 occurred occur VBD cord-006870-f5w6fw6q 4758 6 within within IN cord-006870-f5w6fw6q 4758 7 12 12 CD cord-006870-f5w6fw6q 4758 8 hours hour NNS cord-006870-f5w6fw6q 4758 9 in in IN cord-006870-f5w6fw6q 4758 10 2 2 CD cord-006870-f5w6fw6q 4758 11 ( ( -LRB- cord-006870-f5w6fw6q 4758 12 18 18 CD cord-006870-f5w6fw6q 4758 13 % % NN cord-006870-f5w6fw6q 4758 14 ) ) -RRB- cord-006870-f5w6fw6q 4758 15 patients patient NNS cord-006870-f5w6fw6q 4758 16 , , , cord-006870-f5w6fw6q 4758 17 24 24 CD cord-006870-f5w6fw6q 4758 18 hours hour NNS cord-006870-f5w6fw6q 4758 19 in in IN cord-006870-f5w6fw6q 4758 20 4 4 CD cord-006870-f5w6fw6q 4758 21 ( ( -LRB- cord-006870-f5w6fw6q 4758 22 36 36 CD cord-006870-f5w6fw6q 4758 23 % % NN cord-006870-f5w6fw6q 4758 24 ) ) -RRB- cord-006870-f5w6fw6q 4758 25 patients patient NNS cord-006870-f5w6fw6q 4758 26 , , , cord-006870-f5w6fw6q 4758 27 48 48 CD cord-006870-f5w6fw6q 4758 28 hours hour NNS cord-006870-f5w6fw6q 4758 29 in in IN cord-006870-f5w6fw6q 4758 30 2 2 CD cord-006870-f5w6fw6q 4758 31 ( ( -LRB- cord-006870-f5w6fw6q 4758 32 18 18 CD cord-006870-f5w6fw6q 4758 33 % % NN cord-006870-f5w6fw6q 4758 34 ) ) -RRB- cord-006870-f5w6fw6q 4758 35 patients patient NNS cord-006870-f5w6fw6q 4758 36 and and CC cord-006870-f5w6fw6q 4758 37 72 72 CD cord-006870-f5w6fw6q 4758 38 hours hour NNS cord-006870-f5w6fw6q 4758 39 in in IN cord-006870-f5w6fw6q 4758 40 2 2 CD cord-006870-f5w6fw6q 4758 41 ( ( -LRB- cord-006870-f5w6fw6q 4758 42 18 18 CD cord-006870-f5w6fw6q 4758 43 % % NN cord-006870-f5w6fw6q 4758 44 ) ) -RRB- cord-006870-f5w6fw6q 4758 45 patients patient NNS cord-006870-f5w6fw6q 4758 46 . . . cord-006870-f5w6fw6q 4759 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4759 2 findings finding NNS cord-006870-f5w6fw6q 4759 3 suggest suggest VBP cord-006870-f5w6fw6q 4759 4 that that IN cord-006870-f5w6fw6q 4759 5 Topiramate Topiramate NNP cord-006870-f5w6fw6q 4759 6 could could MD cord-006870-f5w6fw6q 4759 7 be be VB cord-006870-f5w6fw6q 4759 8 an an DT cord-006870-f5w6fw6q 4759 9 effective effective JJ cord-006870-f5w6fw6q 4759 10 adjunctive adjunctive JJ cord-006870-f5w6fw6q 4759 11 treatment treatment NN cord-006870-f5w6fw6q 4759 12 in in IN cord-006870-f5w6fw6q 4759 13 RSE RSE NNP cord-006870-f5w6fw6q 4759 14 and and CC cord-006870-f5w6fw6q 4759 15 SRSE SRSE NNP cord-006870-f5w6fw6q 4759 16 . . . cord-006870-f5w6fw6q 4760 1 However however RB cord-006870-f5w6fw6q 4760 2 , , , cord-006870-f5w6fw6q 4760 3 prospective prospective JJ cord-006870-f5w6fw6q 4760 4 studies study NNS cord-006870-f5w6fw6q 4760 5 , , , cord-006870-f5w6fw6q 4760 6 including include VBG cord-006870-f5w6fw6q 4760 7 larger large JJR cord-006870-f5w6fw6q 4760 8 number number NN cord-006870-f5w6fw6q 4760 9 of of IN cord-006870-f5w6fw6q 4760 10 patients patient NNS cord-006870-f5w6fw6q 4760 11 are be VBP cord-006870-f5w6fw6q 4760 12 needed need VBN cord-006870-f5w6fw6q 4760 13 to to TO cord-006870-f5w6fw6q 4760 14 confirm confirm VB cord-006870-f5w6fw6q 4760 15 these these DT cord-006870-f5w6fw6q 4760 16 findings finding NNS cord-006870-f5w6fw6q 4760 17 . . . cord-006870-f5w6fw6q 4761 1 Patients patient NNS cord-006870-f5w6fw6q 4761 2 with with IN cord-006870-f5w6fw6q 4761 3 refractory refractory JJ cord-006870-f5w6fw6q 4761 4 status status NN cord-006870-f5w6fw6q 4761 5 epilepticus epilepticus NN cord-006870-f5w6fw6q 4761 6 ( ( -LRB- cord-006870-f5w6fw6q 4761 7 SE SE NNP cord-006870-f5w6fw6q 4761 8 ) ) -RRB- cord-006870-f5w6fw6q 4761 9 require require VB cord-006870-f5w6fw6q 4761 10 multiple multiple JJ cord-006870-f5w6fw6q 4761 11 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 4761 12 drugs drug NNS cord-006870-f5w6fw6q 4761 13 ( ( -LRB- cord-006870-f5w6fw6q 4761 14 AEDs aed NNS cord-006870-f5w6fw6q 4761 15 ) ) -RRB- cord-006870-f5w6fw6q 4761 16 to to TO cord-006870-f5w6fw6q 4761 17 abort abort VB cord-006870-f5w6fw6q 4761 18 seizures seizure NNS cord-006870-f5w6fw6q 4761 19 , , , cord-006870-f5w6fw6q 4761 20 and and CC cord-006870-f5w6fw6q 4761 21 often often RB cord-006870-f5w6fw6q 4761 22 barbiturates barbiturate NNS cord-006870-f5w6fw6q 4761 23 . . . cord-006870-f5w6fw6q 4762 1 There there EX cord-006870-f5w6fw6q 4762 2 is be VBZ cord-006870-f5w6fw6q 4762 3 a a DT cord-006870-f5w6fw6q 4762 4 paucity paucity NN cord-006870-f5w6fw6q 4762 5 of of IN cord-006870-f5w6fw6q 4762 6 data datum NNS cord-006870-f5w6fw6q 4762 7 on on IN cord-006870-f5w6fw6q 4762 8 how how WRB cord-006870-f5w6fw6q 4762 9 to to TO cord-006870-f5w6fw6q 4762 10 wean wean VB cord-006870-f5w6fw6q 4762 11 AEDs aed NNS cord-006870-f5w6fw6q 4762 12 safely safely RB cord-006870-f5w6fw6q 4762 13 once once IN cord-006870-f5w6fw6q 4762 14 seizures seizure NNS cord-006870-f5w6fw6q 4762 15 are be VBP cord-006870-f5w6fw6q 4762 16 controlled control VBN cord-006870-f5w6fw6q 4762 17 while while IN cord-006870-f5w6fw6q 4762 18 minimizing minimize VBG cord-006870-f5w6fw6q 4762 19 medication medication NN cord-006870-f5w6fw6q 4762 20 side side NN cord-006870-f5w6fw6q 4762 21 - - HYPH cord-006870-f5w6fw6q 4762 22 effects effect NNS cord-006870-f5w6fw6q 4762 23 or or CC cord-006870-f5w6fw6q 4762 24 withdrawal withdrawal NN cord-006870-f5w6fw6q 4762 25 symptoms symptom NNS cord-006870-f5w6fw6q 4762 26 . . . cord-006870-f5w6fw6q 4763 1 A a DT cord-006870-f5w6fw6q 4763 2 retrospective retrospective JJ cord-006870-f5w6fw6q 4763 3 review review NN cord-006870-f5w6fw6q 4763 4 of of IN cord-006870-f5w6fw6q 4763 5 160 160 CD cord-006870-f5w6fw6q 4763 6 patients patient NNS cord-006870-f5w6fw6q 4763 7 admitted admit VBN cord-006870-f5w6fw6q 4763 8 to to IN cord-006870-f5w6fw6q 4763 9 Mayo Mayo NNP cord-006870-f5w6fw6q 4763 10 Clinic Clinic NNP cord-006870-f5w6fw6q 4763 11 in in IN cord-006870-f5w6fw6q 4763 12 Rochester Rochester NNP cord-006870-f5w6fw6q 4763 13 , , , cord-006870-f5w6fw6q 4763 14 Minnesota Minnesota NNP cord-006870-f5w6fw6q 4763 15 for for IN cord-006870-f5w6fw6q 4763 16 SE SE NNP cord-006870-f5w6fw6q 4763 17 between between IN cord-006870-f5w6fw6q 4763 18 2006 2006 CD cord-006870-f5w6fw6q 4763 19 and and CC cord-006870-f5w6fw6q 4763 20 2016 2016 CD cord-006870-f5w6fw6q 4763 21 was be VBD cord-006870-f5w6fw6q 4763 22 performed perform VBN cord-006870-f5w6fw6q 4763 23 . . . cord-006870-f5w6fw6q 4764 1 Patient patient JJ cord-006870-f5w6fw6q 4764 2 demographics demographic NNS cord-006870-f5w6fw6q 4764 3 , , , cord-006870-f5w6fw6q 4764 4 SE SE NNP cord-006870-f5w6fw6q 4764 5 type type NN cord-006870-f5w6fw6q 4764 6 ( ( -LRB- cord-006870-f5w6fw6q 4764 7 focal focal JJ cord-006870-f5w6fw6q 4764 8 versus versus IN cord-006870-f5w6fw6q 4764 9 generalized generalized JJ cord-006870-f5w6fw6q 4764 10 , , , cord-006870-f5w6fw6q 4764 11 convulsive convulsive JJ cord-006870-f5w6fw6q 4764 12 , , , cord-006870-f5w6fw6q 4764 13 and and CC cord-006870-f5w6fw6q 4764 14 refractoriness refractoriness NN cord-006870-f5w6fw6q 4764 15 ) ) -RRB- cord-006870-f5w6fw6q 4764 16 , , , cord-006870-f5w6fw6q 4764 17 seizure seizure NN cord-006870-f5w6fw6q 4764 18 etiology etiology NN cord-006870-f5w6fw6q 4764 19 , , , cord-006870-f5w6fw6q 4764 20 AEDs aed NNS cord-006870-f5w6fw6q 4764 21 in in IN cord-006870-f5w6fw6q 4764 22 admission admission NN cord-006870-f5w6fw6q 4764 23 and and CC cord-006870-f5w6fw6q 4764 24 at at IN cord-006870-f5w6fw6q 4764 25 outpatient outpatient NN cord-006870-f5w6fw6q 4764 26 follow follow NN cord-006870-f5w6fw6q 4764 27 - - HYPH cord-006870-f5w6fw6q 4764 28 up up NN cord-006870-f5w6fw6q 4764 29 , , , cord-006870-f5w6fw6q 4764 30 AED AED NNP cord-006870-f5w6fw6q 4764 31 side side NN cord-006870-f5w6fw6q 4764 32 effects effect NNS cord-006870-f5w6fw6q 4764 33 from from IN cord-006870-f5w6fw6q 4764 34 use use NN cord-006870-f5w6fw6q 4764 35 and and CC cord-006870-f5w6fw6q 4764 36 withdrawal withdrawal NN cord-006870-f5w6fw6q 4764 37 , , , cord-006870-f5w6fw6q 4764 38 and and CC cord-006870-f5w6fw6q 4764 39 functional functional JJ cord-006870-f5w6fw6q 4764 40 outcomes outcome NNS cord-006870-f5w6fw6q 4764 41 in in IN cord-006870-f5w6fw6q 4764 42 terms term NNS cord-006870-f5w6fw6q 4764 43 of of IN cord-006870-f5w6fw6q 4764 44 modified modify VBN cord-006870-f5w6fw6q 4764 45 Rankin Rankin NNP cord-006870-f5w6fw6q 4764 46 Scale Scale NNP cord-006870-f5w6fw6q 4764 47 were be VBD cord-006870-f5w6fw6q 4764 48 recorded record VBN cord-006870-f5w6fw6q 4764 49 . . . cord-006870-f5w6fw6q 4765 1 44 44 CD cord-006870-f5w6fw6q 4765 2 of of IN cord-006870-f5w6fw6q 4765 3 160 160 CD cord-006870-f5w6fw6q 4765 4 ( ( -LRB- cord-006870-f5w6fw6q 4765 5 27.5 27.5 CD cord-006870-f5w6fw6q 4765 6 % % NN cord-006870-f5w6fw6q 4765 7 ) ) -RRB- cord-006870-f5w6fw6q 4765 8 patients patient NNS cord-006870-f5w6fw6q 4765 9 had have VBD cord-006870-f5w6fw6q 4765 10 refractory refractory JJ cord-006870-f5w6fw6q 4765 11 SE SE NNP cord-006870-f5w6fw6q 4765 12 , , , cord-006870-f5w6fw6q 4765 13 24 24 CD cord-006870-f5w6fw6q 4765 14 ( ( -LRB- cord-006870-f5w6fw6q 4765 15 15.0 15.0 CD cord-006870-f5w6fw6q 4765 16 % % NN cord-006870-f5w6fw6q 4765 17 ) ) -RRB- cord-006870-f5w6fw6q 4765 18 patients patient NNS cord-006870-f5w6fw6q 4765 19 had have VBD cord-006870-f5w6fw6q 4765 20 refractory refractory JJ cord-006870-f5w6fw6q 4765 21 non non JJ cord-006870-f5w6fw6q 4765 22 - - JJ cord-006870-f5w6fw6q 4765 23 convulsive convulsive JJ cord-006870-f5w6fw6q 4765 24 status status NN cord-006870-f5w6fw6q 4765 25 epilepticus epilepticus NN cord-006870-f5w6fw6q 4765 26 ( ( -LRB- cord-006870-f5w6fw6q 4765 27 NCSE NCSE NNP cord-006870-f5w6fw6q 4765 28 ) ) -RRB- cord-006870-f5w6fw6q 4765 29 , , , cord-006870-f5w6fw6q 4765 30 62 62 CD cord-006870-f5w6fw6q 4765 31 ( ( -LRB- cord-006870-f5w6fw6q 4765 32 38.8 38.8 CD cord-006870-f5w6fw6q 4765 33 % % NN cord-006870-f5w6fw6q 4765 34 ) ) -RRB- cord-006870-f5w6fw6q 4766 1 patients patient NNS cord-006870-f5w6fw6q 4766 2 had have VBD cord-006870-f5w6fw6q 4766 3 convulsive convulsive JJ cord-006870-f5w6fw6q 4766 4 SE SE NNP cord-006870-f5w6fw6q 4766 5 , , , cord-006870-f5w6fw6q 4766 6 18 18 CD cord-006870-f5w6fw6q 4766 7 ( ( -LRB- cord-006870-f5w6fw6q 4766 8 11.2 11.2 CD cord-006870-f5w6fw6q 4766 9 % % NN cord-006870-f5w6fw6q 4766 10 ) ) -RRB- cord-006870-f5w6fw6q 4766 11 patients patient NNS cord-006870-f5w6fw6q 4766 12 had have VBD cord-006870-f5w6fw6q 4766 13 NCSE NCSE NNP cord-006870-f5w6fw6q 4766 14 , , , cord-006870-f5w6fw6q 4766 15 and and CC cord-006870-f5w6fw6q 4766 16 12 12 CD cord-006870-f5w6fw6q 4766 17 ( ( -LRB- cord-006870-f5w6fw6q 4766 18 7.5 7.5 CD cord-006870-f5w6fw6q 4766 19 % % NN cord-006870-f5w6fw6q 4766 20 ) ) -RRB- cord-006870-f5w6fw6q 4766 21 patients patient NNS cord-006870-f5w6fw6q 4766 22 had have VBD cord-006870-f5w6fw6q 4766 23 epilepsia epilepsia NNP cord-006870-f5w6fw6q 4766 24 partialis partialis NNP cord-006870-f5w6fw6q 4766 25 continua continua NNP cord-006870-f5w6fw6q 4766 26 . . . cord-006870-f5w6fw6q 4767 1 Of of IN cord-006870-f5w6fw6q 4767 2 the the DT cord-006870-f5w6fw6q 4767 3 122 122 CD cord-006870-f5w6fw6q 4767 4 patients patient NNS cord-006870-f5w6fw6q 4767 5 with with IN cord-006870-f5w6fw6q 4767 6 outpatient outpatient NN cord-006870-f5w6fw6q 4767 7 follow follow NN cord-006870-f5w6fw6q 4767 8 - - HYPH cord-006870-f5w6fw6q 4767 9 up up NN cord-006870-f5w6fw6q 4767 10 ( ( -LRB- cord-006870-f5w6fw6q 4767 11 ranging range VBG cord-006870-f5w6fw6q 4767 12 1 1 CD cord-006870-f5w6fw6q 4767 13 to to TO cord-006870-f5w6fw6q 4767 14 50 50 CD cord-006870-f5w6fw6q 4767 15 weeks week NNS cord-006870-f5w6fw6q 4767 16 following follow VBG cord-006870-f5w6fw6q 4767 17 hospital hospital NN cord-006870-f5w6fw6q 4767 18 discharge discharge NN cord-006870-f5w6fw6q 4767 19 with with IN cord-006870-f5w6fw6q 4767 20 68.0 68.0 CD cord-006870-f5w6fw6q 4767 21 % % NN cord-006870-f5w6fw6q 4767 22 patients patient NNS cord-006870-f5w6fw6q 4767 23 following follow VBG cord-006870-f5w6fw6q 4767 24 - - HYPH cord-006870-f5w6fw6q 4767 25 up up NN cord-006870-f5w6fw6q 4767 26 within within IN cord-006870-f5w6fw6q 4767 27 one one CD cord-006870-f5w6fw6q 4767 28 month month NN cord-006870-f5w6fw6q 4767 29 ) ) -RRB- cord-006870-f5w6fw6q 4767 30 , , , cord-006870-f5w6fw6q 4767 31 120 120 CD cord-006870-f5w6fw6q 4767 32 patients patient NNS cord-006870-f5w6fw6q 4767 33 were be VBD cord-006870-f5w6fw6q 4767 34 on on IN cord-006870-f5w6fw6q 4767 35 an an DT cord-006870-f5w6fw6q 4767 36 AED AED NNP cord-006870-f5w6fw6q 4767 37 regardless regardless RB cord-006870-f5w6fw6q 4767 38 of of IN cord-006870-f5w6fw6q 4767 39 etiology etiology NN cord-006870-f5w6fw6q 4767 40 . . . cord-006870-f5w6fw6q 4768 1 Patients patient NNS cord-006870-f5w6fw6q 4768 2 were be VBD cord-006870-f5w6fw6q 4768 3 on on IN cord-006870-f5w6fw6q 4768 4 a a DT cord-006870-f5w6fw6q 4768 5 median median NN cord-006870-f5w6fw6q 4768 6 of of IN cord-006870-f5w6fw6q 4768 7 1 1 CD cord-006870-f5w6fw6q 4768 8 AED AED NNP cord-006870-f5w6fw6q 4768 9 in in IN cord-006870-f5w6fw6q 4768 10 both both CC cord-006870-f5w6fw6q 4768 11 refractory refractory JJ cord-006870-f5w6fw6q 4768 12 and and CC cord-006870-f5w6fw6q 4768 13 nonrefractory nonrefractory NNP cord-006870-f5w6fw6q 4768 14 SE SE NNP cord-006870-f5w6fw6q 4768 15 at at IN cord-006870-f5w6fw6q 4768 16 follow follow NN cord-006870-f5w6fw6q 4768 17 - - HYPH cord-006870-f5w6fw6q 4768 18 up up NN cord-006870-f5w6fw6q 4768 19 . . . cord-006870-f5w6fw6q 4769 1 9 9 LS cord-006870-f5w6fw6q 4769 2 ( ( -LRB- cord-006870-f5w6fw6q 4769 3 5.6 5.6 CD cord-006870-f5w6fw6q 4769 4 % % NN cord-006870-f5w6fw6q 4769 5 ) ) -RRB- cord-006870-f5w6fw6q 4769 6 patients patient NNS cord-006870-f5w6fw6q 4769 7 had have VBD cord-006870-f5w6fw6q 4769 8 withdrawal withdrawal NN cord-006870-f5w6fw6q 4769 9 seizures seizure NNS cord-006870-f5w6fw6q 4769 10 after after IN cord-006870-f5w6fw6q 4769 11 AEDs aed NNS cord-006870-f5w6fw6q 4769 12 were be VBD cord-006870-f5w6fw6q 4769 13 weaned wean VBN cord-006870-f5w6fw6q 4769 14 ( ( -LRB- cord-006870-f5w6fw6q 4769 15 3 3 CD cord-006870-f5w6fw6q 4769 16 had have VBD cord-006870-f5w6fw6q 4769 17 a a DT cord-006870-f5w6fw6q 4769 18 prior prior JJ cord-006870-f5w6fw6q 4769 19 stroke stroke NN cord-006870-f5w6fw6q 4769 20 , , , cord-006870-f5w6fw6q 4769 21 1 1 CD cord-006870-f5w6fw6q 4769 22 traumatic traumatic JJ cord-006870-f5w6fw6q 4769 23 brain brain NN cord-006870-f5w6fw6q 4769 24 injury injury NN cord-006870-f5w6fw6q 4769 25 , , , cord-006870-f5w6fw6q 4769 26 2 2 CD cord-006870-f5w6fw6q 4769 27 idiopathic idiopathic JJ cord-006870-f5w6fw6q 4769 28 , , , cord-006870-f5w6fw6q 4769 29 2 2 CD cord-006870-f5w6fw6q 4769 30 multifactorial multifactorial NN cord-006870-f5w6fw6q 4769 31 ) ) -RRB- cord-006870-f5w6fw6q 4769 32 . . . cord-006870-f5w6fw6q 4770 1 None none NN cord-006870-f5w6fw6q 4770 2 of of IN cord-006870-f5w6fw6q 4770 3 the the DT cord-006870-f5w6fw6q 4770 4 13 13 CD cord-006870-f5w6fw6q 4770 5 patients patient NNS cord-006870-f5w6fw6q 4770 6 completely completely RB cord-006870-f5w6fw6q 4770 7 weaned wean VBD cord-006870-f5w6fw6q 4770 8 off off RP cord-006870-f5w6fw6q 4770 9 a a DT cord-006870-f5w6fw6q 4770 10 barbiturate barbiturate NN cord-006870-f5w6fw6q 4770 11 had have VBD cord-006870-f5w6fw6q 4770 12 seizure seizure NN cord-006870-f5w6fw6q 4770 13 recurrence recurrence NN cord-006870-f5w6fw6q 4770 14 at at IN cord-006870-f5w6fw6q 4770 15 follow follow NN cord-006870-f5w6fw6q 4770 16 - - HYPH cord-006870-f5w6fw6q 4770 17 up up NN cord-006870-f5w6fw6q 4770 18 . . . cord-006870-f5w6fw6q 4771 1 6-month 6-month CD cord-006870-f5w6fw6q 4771 2 mortality mortality NN cord-006870-f5w6fw6q 4771 3 in in IN cord-006870-f5w6fw6q 4771 4 refractory refractory JJ cord-006870-f5w6fw6q 4771 5 SE SE NNP cord-006870-f5w6fw6q 4771 6 was be VBD cord-006870-f5w6fw6q 4771 7 22/68 22/68 CD cord-006870-f5w6fw6q 4771 8 ( ( -LRB- cord-006870-f5w6fw6q 4771 9 32.4 32.4 CD cord-006870-f5w6fw6q 4771 10 % % NN cord-006870-f5w6fw6q 4771 11 ) ) -RRB- cord-006870-f5w6fw6q 4771 12 and and CC cord-006870-f5w6fw6q 4771 13 23/92 23/92 CD cord-006870-f5w6fw6q 4771 14 ( ( -LRB- cord-006870-f5w6fw6q 4771 15 25.0 25.0 CD cord-006870-f5w6fw6q 4771 16 % % NN cord-006870-f5w6fw6q 4771 17 ) ) -RRB- cord-006870-f5w6fw6q 4771 18 in in IN cord-006870-f5w6fw6q 4771 19 non non JJ cord-006870-f5w6fw6q 4771 20 - - JJ cord-006870-f5w6fw6q 4771 21 refractory refractory JJ cord-006870-f5w6fw6q 4771 22 cases case NNS cord-006870-f5w6fw6q 4771 23 . . . cord-006870-f5w6fw6q 4772 1 Favorable favorable JJ cord-006870-f5w6fw6q 4772 2 functional functional JJ cord-006870-f5w6fw6q 4772 3 outcome outcome NN cord-006870-f5w6fw6q 4772 4 at at IN cord-006870-f5w6fw6q 4772 5 follow follow NN cord-006870-f5w6fw6q 4772 6 - - HYPH cord-006870-f5w6fw6q 4772 7 up up NN cord-006870-f5w6fw6q 4772 8 was be VBD cord-006870-f5w6fw6q 4772 9 achieved achieve VBN cord-006870-f5w6fw6q 4772 10 in in IN cord-006870-f5w6fw6q 4772 11 17/68 17/68 CD cord-006870-f5w6fw6q 4772 12 ( ( -LRB- cord-006870-f5w6fw6q 4772 13 25.0 25.0 CD cord-006870-f5w6fw6q 4772 14 % % NN cord-006870-f5w6fw6q 4772 15 ) ) -RRB- cord-006870-f5w6fw6q 4772 16 patients patient NNS cord-006870-f5w6fw6q 4772 17 with with IN cord-006870-f5w6fw6q 4772 18 refractory refractory JJ cord-006870-f5w6fw6q 4772 19 SE SE NNP cord-006870-f5w6fw6q 4772 20 versus versus IN cord-006870-f5w6fw6q 4772 21 29/92 29/92 CD cord-006870-f5w6fw6q 4772 22 ( ( -LRB- cord-006870-f5w6fw6q 4772 23 31.5 31.5 CD cord-006870-f5w6fw6q 4772 24 % % NN cord-006870-f5w6fw6q 4772 25 ) ) -RRB- cord-006870-f5w6fw6q 4772 26 in in IN cord-006870-f5w6fw6q 4772 27 non non JJ cord-006870-f5w6fw6q 4772 28 - - JJ cord-006870-f5w6fw6q 4772 29 refractory refractory JJ cord-006870-f5w6fw6q 4772 30 SE se NN cord-006870-f5w6fw6q 4772 31 . . . cord-006870-f5w6fw6q 4773 1 We -PRON- PRP cord-006870-f5w6fw6q 4773 2 found find VBD cord-006870-f5w6fw6q 4773 3 a a DT cord-006870-f5w6fw6q 4773 4 low low JJ cord-006870-f5w6fw6q 4773 5 rate rate NN cord-006870-f5w6fw6q 4773 6 of of IN cord-006870-f5w6fw6q 4773 7 late late JJ cord-006870-f5w6fw6q 4773 8 seizure seizure NN cord-006870-f5w6fw6q 4773 9 recurrence recurrence NN cord-006870-f5w6fw6q 4773 10 after after IN cord-006870-f5w6fw6q 4773 11 weaning wean VBG cord-006870-f5w6fw6q 4773 12 AEDs aed NNS cord-006870-f5w6fw6q 4773 13 in in IN cord-006870-f5w6fw6q 4773 14 refractory refractory JJ cord-006870-f5w6fw6q 4773 15 and and CC cord-006870-f5w6fw6q 4773 16 non non JJ cord-006870-f5w6fw6q 4773 17 - - JJ cord-006870-f5w6fw6q 4773 18 refractory refractory JJ cord-006870-f5w6fw6q 4773 19 SE se NN cord-006870-f5w6fw6q 4773 20 , , , cord-006870-f5w6fw6q 4773 21 particularly particularly RB cord-006870-f5w6fw6q 4773 22 in in IN cord-006870-f5w6fw6q 4773 23 the the DT cord-006870-f5w6fw6q 4773 24 case case NN cord-006870-f5w6fw6q 4773 25 of of IN cord-006870-f5w6fw6q 4773 26 barbiturates barbiturate NNS cord-006870-f5w6fw6q 4773 27 . . . cord-006870-f5w6fw6q 4774 1 Spreading spread VBG cord-006870-f5w6fw6q 4774 2 depolarizations depolarization NNS cord-006870-f5w6fw6q 4774 3 ( ( -LRB- cord-006870-f5w6fw6q 4774 4 SD sd NN cord-006870-f5w6fw6q 4774 5 ) ) -RRB- cord-006870-f5w6fw6q 4774 6 are be VBP cord-006870-f5w6fw6q 4774 7 strongly strongly RB cord-006870-f5w6fw6q 4774 8 associated associate VBN cord-006870-f5w6fw6q 4774 9 with with IN cord-006870-f5w6fw6q 4774 10 secondary secondary JJ cord-006870-f5w6fw6q 4774 11 brain brain NN cord-006870-f5w6fw6q 4774 12 injury injury NN cord-006870-f5w6fw6q 4774 13 after after IN cord-006870-f5w6fw6q 4774 14 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4774 15 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4774 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4774 17 ( ( -LRB- cord-006870-f5w6fw6q 4774 18 SAH SAH NNP cord-006870-f5w6fw6q 4774 19 ) ) -RRB- cord-006870-f5w6fw6q 4774 20 . . . cord-006870-f5w6fw6q 4775 1 However however RB cord-006870-f5w6fw6q 4775 2 , , , cord-006870-f5w6fw6q 4775 3 studies study NNS cord-006870-f5w6fw6q 4775 4 to to TO cord-006870-f5w6fw6q 4775 5 understand understand VB cord-006870-f5w6fw6q 4775 6 whether whether IN cord-006870-f5w6fw6q 4775 7 SDs SDs NNP cord-006870-f5w6fw6q 4775 8 play play VBP cord-006870-f5w6fw6q 4775 9 a a DT cord-006870-f5w6fw6q 4775 10 causal causal JJ cord-006870-f5w6fw6q 4775 11 role role NN cord-006870-f5w6fw6q 4775 12 in in IN cord-006870-f5w6fw6q 4775 13 secondary secondary JJ cord-006870-f5w6fw6q 4775 14 injury injury NN cord-006870-f5w6fw6q 4775 15 are be VBP cord-006870-f5w6fw6q 4775 16 hindered hinder VBN cord-006870-f5w6fw6q 4775 17 by by IN cord-006870-f5w6fw6q 4775 18 existing exist VBG cord-006870-f5w6fw6q 4775 19 SD sd NN cord-006870-f5w6fw6q 4775 20 induction induction NN cord-006870-f5w6fw6q 4775 21 methods method NNS cord-006870-f5w6fw6q 4775 22 which which WDT cord-006870-f5w6fw6q 4775 23 are be VBP cord-006870-f5w6fw6q 4775 24 invasive invasive JJ cord-006870-f5w6fw6q 4775 25 , , , cord-006870-f5w6fw6q 4775 26 cumbersome cumbersome JJ cord-006870-f5w6fw6q 4775 27 , , , cord-006870-f5w6fw6q 4775 28 and and CC cord-006870-f5w6fw6q 4775 29 cause cause VB cord-006870-f5w6fw6q 4775 30 primary primary JJ cord-006870-f5w6fw6q 4775 31 tissue tissue NN cord-006870-f5w6fw6q 4775 32 injury injury NN cord-006870-f5w6fw6q 4775 33 . . . cord-006870-f5w6fw6q 4776 1 We -PRON- PRP cord-006870-f5w6fw6q 4776 2 developed develop VBD cord-006870-f5w6fw6q 4776 3 a a DT cord-006870-f5w6fw6q 4776 4 method method NN cord-006870-f5w6fw6q 4776 5 to to TO cord-006870-f5w6fw6q 4776 6 study study VB cord-006870-f5w6fw6q 4776 7 the the DT cord-006870-f5w6fw6q 4776 8 role role NN cord-006870-f5w6fw6q 4776 9 of of IN cord-006870-f5w6fw6q 4776 10 SDs SDs NNP cord-006870-f5w6fw6q 4776 11 after after IN cord-006870-f5w6fw6q 4776 12 experimental experimental JJ cord-006870-f5w6fw6q 4776 13 SAH SAH NNP cord-006870-f5w6fw6q 4776 14 using use VBG cord-006870-f5w6fw6q 4776 15 commercially commercially RB cord-006870-f5w6fw6q 4776 16 available available JJ cord-006870-f5w6fw6q 4776 17 transgenic transgenic JJ cord-006870-f5w6fw6q 4776 18 optogenetic optogenetic JJ cord-006870-f5w6fw6q 4776 19 mice mouse NNS cord-006870-f5w6fw6q 4776 20 which which WDT cord-006870-f5w6fw6q 4776 21 express express VBP cord-006870-f5w6fw6q 4776 22 channelrhodopsin channelrhodopsin NNP cord-006870-f5w6fw6q 4776 23 ( ( -LRB- cord-006870-f5w6fw6q 4776 24 ChR2 ChR2 NNP cord-006870-f5w6fw6q 4776 25 ) ) -RRB- cord-006870-f5w6fw6q 4776 26 in in IN cord-006870-f5w6fw6q 4776 27 cortical cortical JJ cord-006870-f5w6fw6q 4776 28 neurons neuron NNS cord-006870-f5w6fw6q 4776 29 . . . cord-006870-f5w6fw6q 4777 1 We -PRON- PRP cord-006870-f5w6fw6q 4777 2 used use VBD cord-006870-f5w6fw6q 4777 3 in in IN cord-006870-f5w6fw6q 4777 4 vivo vivo NN cord-006870-f5w6fw6q 4777 5 laser laser NN cord-006870-f5w6fw6q 4777 6 speckle speckle NN cord-006870-f5w6fw6q 4777 7 and and CC cord-006870-f5w6fw6q 4777 8 Doppler Doppler NNP cord-006870-f5w6fw6q 4777 9 flowmetry flowmetry NNP cord-006870-f5w6fw6q 4777 10 , , , cord-006870-f5w6fw6q 4777 11 intrinsic intrinsic JJ cord-006870-f5w6fw6q 4777 12 signal signal NN cord-006870-f5w6fw6q 4777 13 imaging imaging NN cord-006870-f5w6fw6q 4777 14 , , , cord-006870-f5w6fw6q 4777 15 and and CC cord-006870-f5w6fw6q 4777 16 local local JJ cord-006870-f5w6fw6q 4777 17 field field NN cord-006870-f5w6fw6q 4777 18 potential potential NN cord-006870-f5w6fw6q 4777 19 ( ( -LRB- cord-006870-f5w6fw6q 4777 20 LFP LFP NNP cord-006870-f5w6fw6q 4777 21 ) ) -RRB- cord-006870-f5w6fw6q 4777 22 and and CC cord-006870-f5w6fw6q 4777 23 extracellular extracellular JJ cord-006870-f5w6fw6q 4777 24 potassium potassium NN cord-006870-f5w6fw6q 4777 25 shifts shift NNS cord-006870-f5w6fw6q 4777 26 to to TO cord-006870-f5w6fw6q 4777 27 detect detect VB cord-006870-f5w6fw6q 4777 28 SDs SDs NNP cord-006870-f5w6fw6q 4777 29 . . . cord-006870-f5w6fw6q 4778 1 We -PRON- PRP cord-006870-f5w6fw6q 4778 2 optogenetically optogenetically RB cord-006870-f5w6fw6q 4778 3 induced induce VBD cord-006870-f5w6fw6q 4778 4 SDs SDs NNP cord-006870-f5w6fw6q 4778 5 with with IN cord-006870-f5w6fw6q 4778 6 light light NN cord-006870-f5w6fw6q 4778 7 through through IN cord-006870-f5w6fw6q 4778 8 intact intact JJ cord-006870-f5w6fw6q 4778 9 and and CC cord-006870-f5w6fw6q 4778 10 unaltered unaltered JJ cord-006870-f5w6fw6q 4778 11 skull skull NN cord-006870-f5w6fw6q 4778 12 in in IN cord-006870-f5w6fw6q 4778 13 multiple multiple JJ cord-006870-f5w6fw6q 4778 14 regions region NNS cord-006870-f5w6fw6q 4778 15 without without IN cord-006870-f5w6fw6q 4778 16 causing cause VBG cord-006870-f5w6fw6q 4778 17 primary primary JJ cord-006870-f5w6fw6q 4778 18 brain brain NN cord-006870-f5w6fw6q 4778 19 injury injury NN cord-006870-f5w6fw6q 4778 20 . . . cord-006870-f5w6fw6q 4779 1 We -PRON- PRP cord-006870-f5w6fw6q 4779 2 found find VBD cord-006870-f5w6fw6q 4779 3 regional regional JJ cord-006870-f5w6fw6q 4779 4 differences difference NNS cord-006870-f5w6fw6q 4779 5 in in IN cord-006870-f5w6fw6q 4779 6 thresholds threshold NNS cord-006870-f5w6fw6q 4779 7 for for IN cord-006870-f5w6fw6q 4779 8 optogenetically optogenetically RB cord-006870-f5w6fw6q 4779 9 - - HYPH cord-006870-f5w6fw6q 4779 10 induced induce VBN cord-006870-f5w6fw6q 4779 11 SDs sds NN cord-006870-f5w6fw6q 4779 12 ( ( -LRB- cord-006870-f5w6fw6q 4779 13 from from IN cord-006870-f5w6fw6q 4779 14 lowest low JJS cord-006870-f5w6fw6q 4779 15 to to IN cord-006870-f5w6fw6q 4779 16 highest high JJS cord-006870-f5w6fw6q 4779 17 threshold threshold NN cord-006870-f5w6fw6q 4779 18 ) ) -RRB- cord-006870-f5w6fw6q 4779 19 : : : cord-006870-f5w6fw6q 4779 20 ( ( -LRB- cord-006870-f5w6fw6q 4779 21 1 1 LS cord-006870-f5w6fw6q 4779 22 ) ) -RRB- cord-006870-f5w6fw6q 4779 23 whisker whisker NN cord-006870-f5w6fw6q 4779 24 barrel barrel NN cord-006870-f5w6fw6q 4779 25 , , , cord-006870-f5w6fw6q 4779 26 ( ( -LRB- cord-006870-f5w6fw6q 4779 27 2 2 LS cord-006870-f5w6fw6q 4779 28 ) ) -RRB- cord-006870-f5w6fw6q 4779 29 motor motor NN cord-006870-f5w6fw6q 4779 30 , , , cord-006870-f5w6fw6q 4779 31 ( ( -LRB- cord-006870-f5w6fw6q 4779 32 3 3 CD cord-006870-f5w6fw6q 4779 33 ) ) -RRB- cord-006870-f5w6fw6q 4779 34 sensory sensory NN cord-006870-f5w6fw6q 4779 35 , , , cord-006870-f5w6fw6q 4779 36 and and CC cord-006870-f5w6fw6q 4779 37 ( ( -LRB- cord-006870-f5w6fw6q 4779 38 4 4 LS cord-006870-f5w6fw6q 4779 39 ) ) -RRB- cord-006870-f5w6fw6q 4779 40 visual visual JJ cord-006870-f5w6fw6q 4779 41 cortex cortex NN cord-006870-f5w6fw6q 4779 42 . . . cord-006870-f5w6fw6q 4780 1 Lower low JJR cord-006870-f5w6fw6q 4780 2 thresholds threshold NNS cord-006870-f5w6fw6q 4780 3 were be VBD cord-006870-f5w6fw6q 4780 4 associated associate VBN cord-006870-f5w6fw6q 4780 5 with with IN cord-006870-f5w6fw6q 4780 6 higher high JJR cord-006870-f5w6fw6q 4780 7 ChR2 ChR2 NNS cord-006870-f5w6fw6q 4780 8 tissue tissue NN cord-006870-f5w6fw6q 4780 9 expression expression NN cord-006870-f5w6fw6q 4780 10 . . . cord-006870-f5w6fw6q 4781 1 Changes change NNS cord-006870-f5w6fw6q 4781 2 in in IN cord-006870-f5w6fw6q 4781 3 LFP LFP NNP cord-006870-f5w6fw6q 4781 4 and and CC cord-006870-f5w6fw6q 4781 5 increased increase VBD cord-006870-f5w6fw6q 4781 6 extracellular extracellular JJ cord-006870-f5w6fw6q 4781 7 potassium potassium NN cord-006870-f5w6fw6q 4781 8 concentrations concentration NNS cord-006870-f5w6fw6q 4781 9 at at IN cord-006870-f5w6fw6q 4781 10 the the DT cord-006870-f5w6fw6q 4781 11 site site NN cord-006870-f5w6fw6q 4781 12 of of IN cord-006870-f5w6fw6q 4781 13 stimulation stimulation NN cord-006870-f5w6fw6q 4781 14 preceded precede VBD cord-006870-f5w6fw6q 4781 15 precipitation precipitation NN cord-006870-f5w6fw6q 4781 16 of of IN cord-006870-f5w6fw6q 4781 17 an an DT cord-006870-f5w6fw6q 4781 18 SD sd NN cord-006870-f5w6fw6q 4781 19 . . . cord-006870-f5w6fw6q 4782 1 Finally finally RB cord-006870-f5w6fw6q 4782 2 , , , cord-006870-f5w6fw6q 4782 3 we -PRON- PRP cord-006870-f5w6fw6q 4782 4 induced induce VBD cord-006870-f5w6fw6q 4782 5 and and CC cord-006870-f5w6fw6q 4782 6 detected detect VBD cord-006870-f5w6fw6q 4782 7 SDs sds NN cord-006870-f5w6fw6q 4782 8 in in IN cord-006870-f5w6fw6q 4782 9 the the DT cord-006870-f5w6fw6q 4782 10 setting setting NN cord-006870-f5w6fw6q 4782 11 of of IN cord-006870-f5w6fw6q 4782 12 SAH SAH NNP cord-006870-f5w6fw6q 4782 13 over over IN cord-006870-f5w6fw6q 4782 14 several several JJ cord-006870-f5w6fw6q 4782 15 days day NNS cord-006870-f5w6fw6q 4782 16 through through IN cord-006870-f5w6fw6q 4782 17 chronically chronically RB cord-006870-f5w6fw6q 4782 18 implanted implant VBN cord-006870-f5w6fw6q 4782 19 glass glass NN cord-006870-f5w6fw6q 4782 20 coverslips coverslip NNS cord-006870-f5w6fw6q 4782 21 Non non JJ cord-006870-f5w6fw6q 4782 22 - - JJ cord-006870-f5w6fw6q 4782 23 invasive invasive JJ cord-006870-f5w6fw6q 4782 24 optogenetic optogenetic JJ cord-006870-f5w6fw6q 4782 25 light light JJ cord-006870-f5w6fw6q 4782 26 stimulation stimulation NN cord-006870-f5w6fw6q 4782 27 can can MD cord-006870-f5w6fw6q 4782 28 reliably reliably RB cord-006870-f5w6fw6q 4782 29 induce induce VB cord-006870-f5w6fw6q 4782 30 SDs sds NN cord-006870-f5w6fw6q 4782 31 in in IN cord-006870-f5w6fw6q 4782 32 the the DT cord-006870-f5w6fw6q 4782 33 setting setting NN cord-006870-f5w6fw6q 4782 34 of of IN cord-006870-f5w6fw6q 4782 35 SAH SAH NNP cord-006870-f5w6fw6q 4782 36 . . . cord-006870-f5w6fw6q 4783 1 Longitudinal longitudinal JJ cord-006870-f5w6fw6q 4783 2 optogenetic optogenetic JJ cord-006870-f5w6fw6q 4783 3 induction induction NN cord-006870-f5w6fw6q 4783 4 of of IN cord-006870-f5w6fw6q 4783 5 SDs SDs NNP cord-006870-f5w6fw6q 4783 6 in in IN cord-006870-f5w6fw6q 4783 7 ChR2 ChR2 NNP cord-006870-f5w6fw6q 4783 8 transgenic transgenic JJ cord-006870-f5w6fw6q 4783 9 mice mouse NNS cord-006870-f5w6fw6q 4783 10 is be VBZ cord-006870-f5w6fw6q 4783 11 a a DT cord-006870-f5w6fw6q 4783 12 potentially potentially RB cord-006870-f5w6fw6q 4783 13 useful useful JJ cord-006870-f5w6fw6q 4783 14 tool tool NN cord-006870-f5w6fw6q 4783 15 to to TO cord-006870-f5w6fw6q 4783 16 study study VB cord-006870-f5w6fw6q 4783 17 the the DT cord-006870-f5w6fw6q 4783 18 role role NN cord-006870-f5w6fw6q 4783 19 of of IN cord-006870-f5w6fw6q 4783 20 SDs sds NN cord-006870-f5w6fw6q 4783 21 in in IN cord-006870-f5w6fw6q 4783 22 the the DT cord-006870-f5w6fw6q 4783 23 pathogenesis pathogenesis NN cord-006870-f5w6fw6q 4783 24 of of IN cord-006870-f5w6fw6q 4783 25 secondary secondary JJ cord-006870-f5w6fw6q 4783 26 brain brain NN cord-006870-f5w6fw6q 4783 27 injury injury NN cord-006870-f5w6fw6q 4783 28 after after IN cord-006870-f5w6fw6q 4783 29 SAH SAH NNP cord-006870-f5w6fw6q 4783 30 . . . cord-006870-f5w6fw6q 4784 1 Aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 4784 2 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4784 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4784 4 is be VBZ cord-006870-f5w6fw6q 4784 5 a a DT cord-006870-f5w6fw6q 4784 6 devastating devastating JJ cord-006870-f5w6fw6q 4784 7 neurologic neurologic JJ cord-006870-f5w6fw6q 4784 8 injury injury NN cord-006870-f5w6fw6q 4784 9 with with IN cord-006870-f5w6fw6q 4784 10 significantly significantly RB cord-006870-f5w6fw6q 4784 11 prolonged prolong VBN cord-006870-f5w6fw6q 4784 12 hospital hospital NN cord-006870-f5w6fw6q 4784 13 courses course NNS cord-006870-f5w6fw6q 4784 14 and and CC cord-006870-f5w6fw6q 4784 15 high high JJ cord-006870-f5w6fw6q 4784 16 morbidity morbidity NN cord-006870-f5w6fw6q 4784 17 and and CC cord-006870-f5w6fw6q 4784 18 mortality mortality NN cord-006870-f5w6fw6q 4784 19 . . . cord-006870-f5w6fw6q 4785 1 When when WRB cord-006870-f5w6fw6q 4785 2 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4785 3 are be VBP cord-006870-f5w6fw6q 4785 4 detected detect VBN cord-006870-f5w6fw6q 4785 5 , , , cord-006870-f5w6fw6q 4785 6 they -PRON- PRP cord-006870-f5w6fw6q 4785 7 often often RB cord-006870-f5w6fw6q 4785 8 require require VBP cord-006870-f5w6fw6q 4785 9 securement securement JJ cord-006870-f5w6fw6q 4785 10 either either CC cord-006870-f5w6fw6q 4785 11 via via IN cord-006870-f5w6fw6q 4785 12 surgical surgical JJ cord-006870-f5w6fw6q 4785 13 clipping clipping NN cord-006870-f5w6fw6q 4785 14 or or CC cord-006870-f5w6fw6q 4785 15 endovascular endovascular JJ cord-006870-f5w6fw6q 4785 16 techniques technique NNS cord-006870-f5w6fw6q 4785 17 . . . cord-006870-f5w6fw6q 4786 1 A a DT cord-006870-f5w6fw6q 4786 2 subset subset NN cord-006870-f5w6fw6q 4786 3 of of IN cord-006870-f5w6fw6q 4786 4 intracranial intracranial JJ cord-006870-f5w6fw6q 4786 5 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4786 6 , , , cord-006870-f5w6fw6q 4786 7 given give VBN cord-006870-f5w6fw6q 4786 8 location location NN cord-006870-f5w6fw6q 4786 9 , , , cord-006870-f5w6fw6q 4786 10 poor poor JJ cord-006870-f5w6fw6q 4786 11 surgical surgical JJ cord-006870-f5w6fw6q 4786 12 approach approach NN cord-006870-f5w6fw6q 4786 13 , , , cord-006870-f5w6fw6q 4786 14 and and CC cord-006870-f5w6fw6q 4786 15 wide wide JJ cord-006870-f5w6fw6q 4786 16 neck neck NN cord-006870-f5w6fw6q 4786 17 are be VBP cord-006870-f5w6fw6q 4786 18 amenable amenable JJ cord-006870-f5w6fw6q 4786 19 to to TO cord-006870-f5w6fw6q 4786 20 flow flow VB cord-006870-f5w6fw6q 4786 21 diversion diversion NN cord-006870-f5w6fw6q 4786 22 which which WDT cord-006870-f5w6fw6q 4786 23 promotes promote VBZ cord-006870-f5w6fw6q 4786 24 thrombosis thrombosis NN cord-006870-f5w6fw6q 4786 25 through through IN cord-006870-f5w6fw6q 4786 26 redirecting redirect VBG cord-006870-f5w6fw6q 4786 27 of of IN cord-006870-f5w6fw6q 4786 28 blood blood NN cord-006870-f5w6fw6q 4786 29 flow flow NN cord-006870-f5w6fw6q 4786 30 within within IN cord-006870-f5w6fw6q 4786 31 an an DT cord-006870-f5w6fw6q 4786 32 aneurysm aneurysm NN cord-006870-f5w6fw6q 4786 33 leading lead VBG cord-006870-f5w6fw6q 4786 34 to to IN cord-006870-f5w6fw6q 4786 35 slow slow JJ cord-006870-f5w6fw6q 4786 36 obliteration obliteration NN cord-006870-f5w6fw6q 4786 37 . . . cord-006870-f5w6fw6q 4787 1 Approximately approximately RB cord-006870-f5w6fw6q 4787 2 10 10 CD cord-006870-f5w6fw6q 4787 3 % % NN cord-006870-f5w6fw6q 4787 4 of of IN cord-006870-f5w6fw6q 4787 5 treated treat VBN cord-006870-f5w6fw6q 4787 6 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4787 7 with with IN cord-006870-f5w6fw6q 4787 8 flow flow NN cord-006870-f5w6fw6q 4787 9 diversion diversion NN cord-006870-f5w6fw6q 4787 10 do do VBP cord-006870-f5w6fw6q 4787 11 not not RB cord-006870-f5w6fw6q 4787 12 obliterate obliterate VB cord-006870-f5w6fw6q 4787 13 after after IN cord-006870-f5w6fw6q 4787 14 12 12 CD cord-006870-f5w6fw6q 4787 15 months month NNS cord-006870-f5w6fw6q 4787 16 , , , cord-006870-f5w6fw6q 4787 17 but but CC cord-006870-f5w6fw6q 4787 18 currently currently RB cord-006870-f5w6fw6q 4787 19 there there EX cord-006870-f5w6fw6q 4787 20 is be VBZ cord-006870-f5w6fw6q 4787 21 no no DT cord-006870-f5w6fw6q 4787 22 validated validated JJ cord-006870-f5w6fw6q 4787 23 way way NN cord-006870-f5w6fw6q 4787 24 to to TO cord-006870-f5w6fw6q 4787 25 predict predict VB cord-006870-f5w6fw6q 4787 26 treatment treatment NN cord-006870-f5w6fw6q 4787 27 failure failure NN cord-006870-f5w6fw6q 4787 28 . . . cord-006870-f5w6fw6q 4788 1 Computational computational JJ cord-006870-f5w6fw6q 4788 2 models model NNS cord-006870-f5w6fw6q 4788 3 of of IN cord-006870-f5w6fw6q 4788 4 blood blood NN cord-006870-f5w6fw6q 4788 5 flow flow NN cord-006870-f5w6fw6q 4788 6 of of IN cord-006870-f5w6fw6q 4788 7 flow flow NN cord-006870-f5w6fw6q 4788 8 diverted divert VBN cord-006870-f5w6fw6q 4788 9 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4788 10 predict predict VBP cord-006870-f5w6fw6q 4788 11 a a DT cord-006870-f5w6fw6q 4788 12 significant significant JJ cord-006870-f5w6fw6q 4788 13 difference difference NN cord-006870-f5w6fw6q 4788 14 in in IN cord-006870-f5w6fw6q 4788 15 the the DT cord-006870-f5w6fw6q 4788 16 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 4788 17 energy energy NN cord-006870-f5w6fw6q 4788 18 loss loss NN cord-006870-f5w6fw6q 4788 19 across across IN cord-006870-f5w6fw6q 4788 20 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4788 21 between between IN cord-006870-f5w6fw6q 4788 22 cases case NNS cord-006870-f5w6fw6q 4788 23 that that WDT cord-006870-f5w6fw6q 4788 24 resolve resolve VBP cord-006870-f5w6fw6q 4788 25 and and CC cord-006870-f5w6fw6q 4788 26 those those DT cord-006870-f5w6fw6q 4788 27 that that WDT cord-006870-f5w6fw6q 4788 28 do do VBP cord-006870-f5w6fw6q 4788 29 not not RB cord-006870-f5w6fw6q 4788 30 . . . cord-006870-f5w6fw6q 4789 1 Energy energy NN cord-006870-f5w6fw6q 4789 2 loss loss NN cord-006870-f5w6fw6q 4789 3 could could MD cord-006870-f5w6fw6q 4789 4 be be VB cord-006870-f5w6fw6q 4789 5 estimated estimate VBN cord-006870-f5w6fw6q 4789 6 clinically clinically RB cord-006870-f5w6fw6q 4789 7 during during IN cord-006870-f5w6fw6q 4789 8 angiography angiography NN cord-006870-f5w6fw6q 4789 9 , , , cord-006870-f5w6fw6q 4789 10 however however RB cord-006870-f5w6fw6q 4789 11 , , , cord-006870-f5w6fw6q 4789 12 this this DT cord-006870-f5w6fw6q 4789 13 hypothesis hypothesis NN cord-006870-f5w6fw6q 4789 14 needs need VBZ cord-006870-f5w6fw6q 4789 15 to to TO cord-006870-f5w6fw6q 4789 16 be be VB cord-006870-f5w6fw6q 4789 17 validated validate VBN cord-006870-f5w6fw6q 4789 18 experimentally experimentally RB cord-006870-f5w6fw6q 4789 19 because because IN cord-006870-f5w6fw6q 4789 20 computer computer NN cord-006870-f5w6fw6q 4789 21 models model NNS cord-006870-f5w6fw6q 4789 22 often often RB cord-006870-f5w6fw6q 4789 23 over over IN cord-006870-f5w6fw6q 4789 24 estimate estimate VBP cord-006870-f5w6fw6q 4789 25 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 4789 26 parameters parameter NNS cord-006870-f5w6fw6q 4789 27 , , , cord-006870-f5w6fw6q 4789 28 poorly poorly RB cord-006870-f5w6fw6q 4789 29 predict predict VB cord-006870-f5w6fw6q 4789 30 flow flow NN cord-006870-f5w6fw6q 4789 31 through through IN cord-006870-f5w6fw6q 4789 32 stents stent NNS cord-006870-f5w6fw6q 4789 33 , , , cord-006870-f5w6fw6q 4789 34 and and CC cord-006870-f5w6fw6q 4789 35 may may MD cord-006870-f5w6fw6q 4789 36 not not RB cord-006870-f5w6fw6q 4789 37 have have VB cord-006870-f5w6fw6q 4789 38 the the DT cord-006870-f5w6fw6q 4789 39 resolution resolution NN cord-006870-f5w6fw6q 4789 40 to to TO cord-006870-f5w6fw6q 4789 41 fully fully RB cord-006870-f5w6fw6q 4789 42 describe describe VB cord-006870-f5w6fw6q 4789 43 intra intra JJ cord-006870-f5w6fw6q 4789 44 - - JJ cord-006870-f5w6fw6q 4789 45 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 4789 46 blood blood NN cord-006870-f5w6fw6q 4789 47 flow flow NN cord-006870-f5w6fw6q 4789 48 . . . cord-006870-f5w6fw6q 4790 1 In in IN cord-006870-f5w6fw6q 4790 2 this this DT cord-006870-f5w6fw6q 4790 3 pilot pilot NN cord-006870-f5w6fw6q 4790 4 study study NN cord-006870-f5w6fw6q 4790 5 , , , cord-006870-f5w6fw6q 4790 6 four four CD cord-006870-f5w6fw6q 4790 7 cases case NNS cord-006870-f5w6fw6q 4790 8 of of IN cord-006870-f5w6fw6q 4790 9 giant giant JJ cord-006870-f5w6fw6q 4790 10 fusiform fusiform JJ cord-006870-f5w6fw6q 4790 11 intracranial intracranial JJ cord-006870-f5w6fw6q 4790 12 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4790 13 will will MD cord-006870-f5w6fw6q 4790 14 be be VB cord-006870-f5w6fw6q 4790 15 selected select VBN cord-006870-f5w6fw6q 4790 16 --two --two CD cord-006870-f5w6fw6q 4790 17 with with IN cord-006870-f5w6fw6q 4790 18 resolution resolution NN cord-006870-f5w6fw6q 4790 19 following follow VBG cord-006870-f5w6fw6q 4790 20 flow flow NN cord-006870-f5w6fw6q 4790 21 diversion diversion NN cord-006870-f5w6fw6q 4790 22 treatment treatment NN cord-006870-f5w6fw6q 4790 23 , , , cord-006870-f5w6fw6q 4790 24 and and CC cord-006870-f5w6fw6q 4790 25 two two CD cord-006870-f5w6fw6q 4790 26 without without IN cord-006870-f5w6fw6q 4790 27 resolution resolution NN cord-006870-f5w6fw6q 4790 28 . . . cord-006870-f5w6fw6q 4791 1 Models model NNS cord-006870-f5w6fw6q 4791 2 of of IN cord-006870-f5w6fw6q 4791 3 each each DT cord-006870-f5w6fw6q 4791 4 vessel vessel NN cord-006870-f5w6fw6q 4791 5 geometry geometry NN cord-006870-f5w6fw6q 4791 6 will will MD cord-006870-f5w6fw6q 4791 7 be be VB cord-006870-f5w6fw6q 4791 8 fabricated fabricate VBN cord-006870-f5w6fw6q 4791 9 using use VBG cord-006870-f5w6fw6q 4791 10 additive additive NN cord-006870-f5w6fw6q 4791 11 manufacturing manufacturing NN cord-006870-f5w6fw6q 4791 12 techniques technique NNS cord-006870-f5w6fw6q 4791 13 . . . cord-006870-f5w6fw6q 4792 1 Under under IN cord-006870-f5w6fw6q 4792 2 fluoroscopy fluoroscopy NN cord-006870-f5w6fw6q 4792 3 , , , cord-006870-f5w6fw6q 4792 4 within within IN cord-006870-f5w6fw6q 4792 5 the the DT cord-006870-f5w6fw6q 4792 6 model model NN cord-006870-f5w6fw6q 4792 7 vessel vessel NN cord-006870-f5w6fw6q 4792 8 , , , cord-006870-f5w6fw6q 4792 9 flow flow VB cord-006870-f5w6fw6q 4792 10 diverting divert VBG cord-006870-f5w6fw6q 4792 11 stents stent NNS cord-006870-f5w6fw6q 4792 12 will will MD cord-006870-f5w6fw6q 4792 13 be be VB cord-006870-f5w6fw6q 4792 14 placed place VBN cord-006870-f5w6fw6q 4792 15 within within IN cord-006870-f5w6fw6q 4792 16 the the DT cord-006870-f5w6fw6q 4792 17 aneurysm aneurysm NN cord-006870-f5w6fw6q 4792 18 in in IN cord-006870-f5w6fw6q 4792 19 the the DT cord-006870-f5w6fw6q 4792 20 same same JJ cord-006870-f5w6fw6q 4792 21 configuration configuration NN cord-006870-f5w6fw6q 4792 22 that that WDT cord-006870-f5w6fw6q 4792 23 was be VBD cord-006870-f5w6fw6q 4792 24 achieved achieve VBN cord-006870-f5w6fw6q 4792 25 clinically clinically RB cord-006870-f5w6fw6q 4792 26 . . . cord-006870-f5w6fw6q 4793 1 Model model NN cord-006870-f5w6fw6q 4793 2 blood blood NN cord-006870-f5w6fw6q 4793 3 , , , cord-006870-f5w6fw6q 4793 4 containing contain VBG cord-006870-f5w6fw6q 4793 5 tracer tracer NN cord-006870-f5w6fw6q 4793 6 particles particle NNS cord-006870-f5w6fw6q 4793 7 will will MD cord-006870-f5w6fw6q 4793 8 be be VB cord-006870-f5w6fw6q 4793 9 pumped pump VBN cord-006870-f5w6fw6q 4793 10 through through IN cord-006870-f5w6fw6q 4793 11 model model NN cord-006870-f5w6fw6q 4793 12 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4793 13 and and CC cord-006870-f5w6fw6q 4793 14 using use VBG cord-006870-f5w6fw6q 4793 15 particle particle NN cord-006870-f5w6fw6q 4793 16 image image NN cord-006870-f5w6fw6q 4793 17 velocimetry velocimetry NN cord-006870-f5w6fw6q 4793 18 , , , cord-006870-f5w6fw6q 4793 19 energy energy NN cord-006870-f5w6fw6q 4793 20 loss loss NN cord-006870-f5w6fw6q 4793 21 will will MD cord-006870-f5w6fw6q 4793 22 be be VB cord-006870-f5w6fw6q 4793 23 calculating calculate VBG cord-006870-f5w6fw6q 4793 24 within within IN cord-006870-f5w6fw6q 4793 25 model model NN cord-006870-f5w6fw6q 4793 26 vessels vessel NNS cord-006870-f5w6fw6q 4793 27 following follow VBG cord-006870-f5w6fw6q 4793 28 treatment treatment NN cord-006870-f5w6fw6q 4793 29 . . . cord-006870-f5w6fw6q 4794 1 Energy energy NN cord-006870-f5w6fw6q 4794 2 loss loss NN cord-006870-f5w6fw6q 4794 3 between between IN cord-006870-f5w6fw6q 4794 4 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4794 5 successfully successfully RB cord-006870-f5w6fw6q 4794 6 and and CC cord-006870-f5w6fw6q 4794 7 unsuccessfully unsuccessfully RB cord-006870-f5w6fw6q 4794 8 treated treat VBN cord-006870-f5w6fw6q 4794 9 with with IN cord-006870-f5w6fw6q 4794 10 flow flow NN cord-006870-f5w6fw6q 4794 11 diversion diversion NN cord-006870-f5w6fw6q 4794 12 will will MD cord-006870-f5w6fw6q 4794 13 be be VB cord-006870-f5w6fw6q 4794 14 compared compare VBN cord-006870-f5w6fw6q 4794 15 experimentally experimentally RB cord-006870-f5w6fw6q 4794 16 . . . cord-006870-f5w6fw6q 4795 1 Hemodynamic Hemodynamic NNP cord-006870-f5w6fw6q 4795 2 energy energy NN cord-006870-f5w6fw6q 4795 3 loss loss NN cord-006870-f5w6fw6q 4795 4 may may MD cord-006870-f5w6fw6q 4795 5 be be VB cord-006870-f5w6fw6q 4795 6 a a DT cord-006870-f5w6fw6q 4795 7 clinically clinically RB cord-006870-f5w6fw6q 4795 8 measurable measurable JJ cord-006870-f5w6fw6q 4795 9 value value NN cord-006870-f5w6fw6q 4795 10 which which WDT cord-006870-f5w6fw6q 4795 11 could could MD cord-006870-f5w6fw6q 4795 12 predict predict VB cord-006870-f5w6fw6q 4795 13 treatment treatment NN cord-006870-f5w6fw6q 4795 14 failure failure NN cord-006870-f5w6fw6q 4795 15 after after IN cord-006870-f5w6fw6q 4795 16 flow flow NN cord-006870-f5w6fw6q 4795 17 diversion diversion NN cord-006870-f5w6fw6q 4795 18 . . . cord-006870-f5w6fw6q 4796 1 Additive additive NN cord-006870-f5w6fw6q 4796 2 manufacturing manufacturing NN cord-006870-f5w6fw6q 4796 3 techniques technique NNS cord-006870-f5w6fw6q 4796 4 can can MD cord-006870-f5w6fw6q 4796 5 be be VB cord-006870-f5w6fw6q 4796 6 used use VBN cord-006870-f5w6fw6q 4796 7 to to TO cord-006870-f5w6fw6q 4796 8 test test VB cord-006870-f5w6fw6q 4796 9 patient patient JJ cord-006870-f5w6fw6q 4796 10 specific specific JJ cord-006870-f5w6fw6q 4796 11 hemodynamics hemodynamic NNS cord-006870-f5w6fw6q 4796 12 to to TO cord-006870-f5w6fw6q 4796 13 improve improve VB cord-006870-f5w6fw6q 4796 14 understanding understanding NN cord-006870-f5w6fw6q 4796 15 of of IN cord-006870-f5w6fw6q 4796 16 flow flow NN cord-006870-f5w6fw6q 4796 17 - - HYPH cord-006870-f5w6fw6q 4796 18 diversion diversion NN cord-006870-f5w6fw6q 4796 19 treatment treatment NN cord-006870-f5w6fw6q 4796 20 success success NN cord-006870-f5w6fw6q 4796 21 or or CC cord-006870-f5w6fw6q 4796 22 failure failure NN cord-006870-f5w6fw6q 4796 23 . . . cord-006870-f5w6fw6q 4797 1 The the DT cord-006870-f5w6fw6q 4797 2 National National NNP cord-006870-f5w6fw6q 4797 3 Institute Institute NNP cord-006870-f5w6fw6q 4797 4 of of IN cord-006870-f5w6fw6q 4797 5 Neurological Neurological NNP cord-006870-f5w6fw6q 4797 6 Disorders Disorders NNPS cord-006870-f5w6fw6q 4797 7 and and CC cord-006870-f5w6fw6q 4797 8 Stroke Stroke NNP cord-006870-f5w6fw6q 4797 9 ( ( -LRB- cord-006870-f5w6fw6q 4797 10 NINDS NINDS NNP cord-006870-f5w6fw6q 4797 11 ) ) -RRB- cord-006870-f5w6fw6q 4797 12 and and CC cord-006870-f5w6fw6q 4797 13 the the DT cord-006870-f5w6fw6q 4797 14 National National NNP cord-006870-f5w6fw6q 4797 15 Library Library NNP cord-006870-f5w6fw6q 4797 16 of of IN cord-006870-f5w6fw6q 4797 17 Medicine Medicine NNP cord-006870-f5w6fw6q 4797 18 ( ( -LRB- cord-006870-f5w6fw6q 4797 19 NLM NLM NNP cord-006870-f5w6fw6q 4797 20 ) ) -RRB- cord-006870-f5w6fw6q 4797 21 initiated initiate VBN cord-006870-f5w6fw6q 4797 22 development development NN cord-006870-f5w6fw6q 4797 23 of of IN cord-006870-f5w6fw6q 4797 24 unruptured unruptured JJ cord-006870-f5w6fw6q 4797 25 cerebral cerebral JJ cord-006870-f5w6fw6q 4797 26 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4797 27 and and CC cord-006870-f5w6fw6q 4797 28 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4797 29 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4797 30 ( ( -LRB- cord-006870-f5w6fw6q 4797 31 SAH)specific SAH)specific NNP cord-006870-f5w6fw6q 4797 32 Common Common NNP cord-006870-f5w6fw6q 4797 33 Data Data NNP cord-006870-f5w6fw6q 4797 34 Elements Elements NNP cord-006870-f5w6fw6q 4797 35 ( ( -LRB- cord-006870-f5w6fw6q 4797 36 CDEs CDEs NNP cord-006870-f5w6fw6q 4797 37 ) ) -RRB- cord-006870-f5w6fw6q 4797 38 in in IN cord-006870-f5w6fw6q 4797 39 2015 2015 CD cord-006870-f5w6fw6q 4797 40 as as IN cord-006870-f5w6fw6q 4797 41 part part NN cord-006870-f5w6fw6q 4797 42 of of IN cord-006870-f5w6fw6q 4797 43 a a DT cord-006870-f5w6fw6q 4797 44 joint joint JJ cord-006870-f5w6fw6q 4797 45 project project NN cord-006870-f5w6fw6q 4797 46 to to TO cord-006870-f5w6fw6q 4797 47 develop develop VB cord-006870-f5w6fw6q 4797 48 data datum NNS cord-006870-f5w6fw6q 4797 49 standards standard NNS cord-006870-f5w6fw6q 4797 50 for for IN cord-006870-f5w6fw6q 4797 51 funded fund VBN cord-006870-f5w6fw6q 4797 52 neuroscience neuroscience NNP cord-006870-f5w6fw6q 4797 53 clinical clinical JJ cord-006870-f5w6fw6q 4797 54 research research NN cord-006870-f5w6fw6q 4797 55 . . . cord-006870-f5w6fw6q 4798 1 Through through IN cord-006870-f5w6fw6q 4798 2 the the DT cord-006870-f5w6fw6q 4798 3 development development NN cord-006870-f5w6fw6q 4798 4 of of IN cord-006870-f5w6fw6q 4798 5 these these DT cord-006870-f5w6fw6q 4798 6 data datum NNS cord-006870-f5w6fw6q 4798 7 standards standard NNS cord-006870-f5w6fw6q 4798 8 , , , cord-006870-f5w6fw6q 4798 9 the the DT cord-006870-f5w6fw6q 4798 10 NINDS NINDS NNP cord-006870-f5w6fw6q 4798 11 and and CC cord-006870-f5w6fw6q 4798 12 NLM NLM NNP cord-006870-f5w6fw6q 4798 13 SAH SAH NNP cord-006870-f5w6fw6q 4798 14 joint joint JJ cord-006870-f5w6fw6q 4798 15 CDE CDE NNP cord-006870-f5w6fw6q 4798 16 initiative initiative NN cord-006870-f5w6fw6q 4798 17 strives strive VBZ cord-006870-f5w6fw6q 4798 18 to to TO cord-006870-f5w6fw6q 4798 19 improve improve VB cord-006870-f5w6fw6q 4798 20 SAH SAH NNP cord-006870-f5w6fw6q 4798 21 data datum NNS cord-006870-f5w6fw6q 4798 22 collection collection NN cord-006870-f5w6fw6q 4798 23 by by IN cord-006870-f5w6fw6q 4798 24 increasing increase VBG cord-006870-f5w6fw6q 4798 25 efficiency efficiency NN cord-006870-f5w6fw6q 4798 26 , , , cord-006870-f5w6fw6q 4798 27 improving improve VBG cord-006870-f5w6fw6q 4798 28 data datum NNS cord-006870-f5w6fw6q 4798 29 quality quality NN cord-006870-f5w6fw6q 4798 30 , , , cord-006870-f5w6fw6q 4798 31 reducing reduce VBG cord-006870-f5w6fw6q 4798 32 study study NN cord-006870-f5w6fw6q 4798 33 start start VB cord-006870-f5w6fw6q 4798 34 - - HYPH cord-006870-f5w6fw6q 4798 35 up up RP cord-006870-f5w6fw6q 4798 36 time time NN cord-006870-f5w6fw6q 4798 37 , , , cord-006870-f5w6fw6q 4798 38 facilitating facilitate VBG cord-006870-f5w6fw6q 4798 39 data datum NNS cord-006870-f5w6fw6q 4798 40 sharing sharing NN cord-006870-f5w6fw6q 4798 41 / / SYM cord-006870-f5w6fw6q 4798 42 meta meta NNP cord-006870-f5w6fw6q 4798 43 - - HYPH cord-006870-f5w6fw6q 4798 44 analyses analysis NNS cord-006870-f5w6fw6q 4798 45 and and CC cord-006870-f5w6fw6q 4798 46 helping help VBG cord-006870-f5w6fw6q 4798 47 educate educate VB cord-006870-f5w6fw6q 4798 48 new new JJ cord-006870-f5w6fw6q 4798 49 clinical clinical JJ cord-006870-f5w6fw6q 4798 50 investigators investigator NNS cord-006870-f5w6fw6q 4798 51 . . . cord-006870-f5w6fw6q 4799 1 The the DT cord-006870-f5w6fw6q 4799 2 SAH SAH NNP cord-006870-f5w6fw6q 4799 3 CDE CDE NNP cord-006870-f5w6fw6q 4799 4 working work VBG cord-006870-f5w6fw6q 4799 5 group group NN cord-006870-f5w6fw6q 4799 6 ( ( -LRB- cord-006870-f5w6fw6q 4799 7 WG WG NNP cord-006870-f5w6fw6q 4799 8 ) ) -RRB- cord-006870-f5w6fw6q 4799 9 consisted consist VBD cord-006870-f5w6fw6q 4799 10 of of IN cord-006870-f5w6fw6q 4799 11 83 83 CD cord-006870-f5w6fw6q 4799 12 international international JJ cord-006870-f5w6fw6q 4799 13 members member NNS cord-006870-f5w6fw6q 4799 14 with with IN cord-006870-f5w6fw6q 4799 15 varied varied JJ cord-006870-f5w6fw6q 4799 16 fields field NNS cord-006870-f5w6fw6q 4799 17 of of IN cord-006870-f5w6fw6q 4799 18 SAHrelated sahrelated JJ cord-006870-f5w6fw6q 4799 19 expertise expertise NN cord-006870-f5w6fw6q 4799 20 and and CC cord-006870-f5w6fw6q 4799 21 was be VBD cord-006870-f5w6fw6q 4799 22 divided divide VBN cord-006870-f5w6fw6q 4799 23 into into IN cord-006870-f5w6fw6q 4799 24 domains domain NNS cord-006870-f5w6fw6q 4799 25 such such JJ cord-006870-f5w6fw6q 4799 26 as as IN cord-006870-f5w6fw6q 4799 27 subject subject JJ cord-006870-f5w6fw6q 4799 28 characteristics characteristic NNS cord-006870-f5w6fw6q 4799 29 and and CC cord-006870-f5w6fw6q 4799 30 assessments assessment NNS cord-006870-f5w6fw6q 4799 31 and and CC cord-006870-f5w6fw6q 4799 32 exams exam NNS cord-006870-f5w6fw6q 4799 33 . . . cord-006870-f5w6fw6q 4800 1 The the DT cord-006870-f5w6fw6q 4800 2 WG WG NNP cord-006870-f5w6fw6q 4800 3 developed develop VBD cord-006870-f5w6fw6q 4800 4 a a DT cord-006870-f5w6fw6q 4800 5 set set NN cord-006870-f5w6fw6q 4800 6 of of IN cord-006870-f5w6fw6q 4800 7 SAH SAH NNP cord-006870-f5w6fw6q 4800 8 - - HYPH cord-006870-f5w6fw6q 4800 9 specific specific JJ cord-006870-f5w6fw6q 4800 10 CDE CDE NNP cord-006870-f5w6fw6q 4800 11 recommendations recommendation NNS cord-006870-f5w6fw6q 4800 12 by by IN cord-006870-f5w6fw6q 4800 13 selecting select VBG cord-006870-f5w6fw6q 4800 14 among among IN cord-006870-f5w6fw6q 4800 15 , , , cord-006870-f5w6fw6q 4800 16 refining refining NN cord-006870-f5w6fw6q 4800 17 and and CC cord-006870-f5w6fw6q 4800 18 adding add VBG cord-006870-f5w6fw6q 4800 19 to to IN cord-006870-f5w6fw6q 4800 20 existing existing JJ cord-006870-f5w6fw6q 4800 21 field field NN cord-006870-f5w6fw6q 4800 22 - - HYPH cord-006870-f5w6fw6q 4800 23 tested test VBN cord-006870-f5w6fw6q 4800 24 data data NN cord-006870-f5w6fw6q 4800 25 elements element NNS cord-006870-f5w6fw6q 4800 26 , , , cord-006870-f5w6fw6q 4800 27 especially especially RB cord-006870-f5w6fw6q 4800 28 established establish VBN cord-006870-f5w6fw6q 4800 29 Stroke stroke NN cord-006870-f5w6fw6q 4800 30 CDEs cde NNS cord-006870-f5w6fw6q 4800 31 . . . cord-006870-f5w6fw6q 4801 1 WG WG NNP cord-006870-f5w6fw6q 4801 2 CDE CDE NNP cord-006870-f5w6fw6q 4801 3 recommendations recommendation NNS cord-006870-f5w6fw6q 4801 4 were be VBD cord-006870-f5w6fw6q 4801 5 drafted draft VBN cord-006870-f5w6fw6q 4801 6 into into IN cord-006870-f5w6fw6q 4801 7 the the DT cord-006870-f5w6fw6q 4801 8 NIH NIH NNP cord-006870-f5w6fw6q 4801 9 CDE CDE NNP cord-006870-f5w6fw6q 4801 10 Repository Repository NNP cord-006870-f5w6fw6q 4801 11 . . . cord-006870-f5w6fw6q 4802 1 Following follow VBG cord-006870-f5w6fw6q 4802 2 an an DT cord-006870-f5w6fw6q 4802 3 internal internal JJ cord-006870-f5w6fw6q 4802 4 review review NN cord-006870-f5w6fw6q 4802 5 of of IN cord-006870-f5w6fw6q 4802 6 recommendations recommendation NNS cord-006870-f5w6fw6q 4802 7 , , , cord-006870-f5w6fw6q 4802 8 the the DT cord-006870-f5w6fw6q 4802 9 SAH SAH NNP cord-006870-f5w6fw6q 4802 10 CDEs cde NNS cord-006870-f5w6fw6q 4802 11 were be VBD cord-006870-f5w6fw6q 4802 12 vetted vet VBN cord-006870-f5w6fw6q 4802 13 during during IN cord-006870-f5w6fw6q 4802 14 a a DT cord-006870-f5w6fw6q 4802 15 public public JJ cord-006870-f5w6fw6q 4802 16 review review NN cord-006870-f5w6fw6q 4802 17 on on IN cord-006870-f5w6fw6q 4802 18 the the DT cord-006870-f5w6fw6q 4802 19 NINDS NINDS NNP cord-006870-f5w6fw6q 4802 20 website website NN cord-006870-f5w6fw6q 4802 21 for for IN cord-006870-f5w6fw6q 4802 22 6 6 CD cord-006870-f5w6fw6q 4802 23 weeks week NNS cord-006870-f5w6fw6q 4802 24 and and CC cord-006870-f5w6fw6q 4802 25 later later RB cord-006870-f5w6fw6q 4802 26 posted post VBN cord-006870-f5w6fw6q 4802 27 on on IN cord-006870-f5w6fw6q 4802 28 NLM NLM NNP cord-006870-f5w6fw6q 4802 29 and and CC cord-006870-f5w6fw6q 4802 30 NINDS NINDS NNP cord-006870-f5w6fw6q 4802 31 websites website NNS cord-006870-f5w6fw6q 4802 32 . . . cord-006870-f5w6fw6q 4803 1 Version version NN cord-006870-f5w6fw6q 4803 2 1.0 1.0 CD cord-006870-f5w6fw6q 4803 3 of of IN cord-006870-f5w6fw6q 4803 4 the the DT cord-006870-f5w6fw6q 4803 5 SAH SAH NNP cord-006870-f5w6fw6q 4803 6 CDEs cde NNS cord-006870-f5w6fw6q 4803 7 was be VBD cord-006870-f5w6fw6q 4803 8 available available JJ cord-006870-f5w6fw6q 4803 9 on on IN cord-006870-f5w6fw6q 4803 10 the the DT cord-006870-f5w6fw6q 4803 11 NINDS NINDS NNP cord-006870-f5w6fw6q 4803 12 CDE CDE NNP cord-006870-f5w6fw6q 4803 13 website website NN cord-006870-f5w6fw6q 4803 14 in in IN cord-006870-f5w6fw6q 4803 15 April April NNP cord-006870-f5w6fw6q 4803 16 2017 2017 CD cord-006870-f5w6fw6q 4803 17 . . . cord-006870-f5w6fw6q 4804 1 These these DT cord-006870-f5w6fw6q 4804 2 new new JJ cord-006870-f5w6fw6q 4804 3 SAH SAH NNP cord-006870-f5w6fw6q 4804 4 CDEs cde NNS cord-006870-f5w6fw6q 4804 5 and and CC cord-006870-f5w6fw6q 4804 6 recommendations recommendation NNS cord-006870-f5w6fw6q 4804 7 include include VBP cord-006870-f5w6fw6q 4804 8 those those DT cord-006870-f5w6fw6q 4804 9 developed develop VBN cord-006870-f5w6fw6q 4804 10 for for IN cord-006870-f5w6fw6q 4804 11 unruptured unruptured JJ cord-006870-f5w6fw6q 4804 12 intracranial intracranial JJ cord-006870-f5w6fw6q 4804 13 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4804 14 and and CC cord-006870-f5w6fw6q 4804 15 long long JJ cord-006870-f5w6fw6q 4804 16 - - HYPH cord-006870-f5w6fw6q 4804 17 term term NN cord-006870-f5w6fw6q 4804 18 therapies therapy NNS cord-006870-f5w6fw6q 4804 19 . . . cord-006870-f5w6fw6q 4805 1 The the DT cord-006870-f5w6fw6q 4805 2 website website NN cord-006870-f5w6fw6q 4805 3 provides provide VBZ cord-006870-f5w6fw6q 4805 4 uniform uniform JJ cord-006870-f5w6fw6q 4805 5 names name NNS cord-006870-f5w6fw6q 4805 6 and and CC cord-006870-f5w6fw6q 4805 7 structures structure NNS cord-006870-f5w6fw6q 4805 8 for for IN cord-006870-f5w6fw6q 4805 9 each each DT cord-006870-f5w6fw6q 4805 10 data data NN cord-006870-f5w6fw6q 4805 11 element element NN cord-006870-f5w6fw6q 4805 12 , , , cord-006870-f5w6fw6q 4805 13 as as RB cord-006870-f5w6fw6q 4805 14 well well RB cord-006870-f5w6fw6q 4805 15 as as IN cord-006870-f5w6fw6q 4805 16 guidance guidance NN cord-006870-f5w6fw6q 4805 17 documents document NNS cord-006870-f5w6fw6q 4805 18 and and CC cord-006870-f5w6fw6q 4805 19 template template NN cord-006870-f5w6fw6q 4805 20 case case NN cord-006870-f5w6fw6q 4805 21 report report NN cord-006870-f5w6fw6q 4805 22 forms form NNS cord-006870-f5w6fw6q 4805 23 using use VBG cord-006870-f5w6fw6q 4805 24 the the DT cord-006870-f5w6fw6q 4805 25 CDEs cde NNS cord-006870-f5w6fw6q 4805 26 . . . cord-006870-f5w6fw6q 4806 1 The the DT cord-006870-f5w6fw6q 4806 2 NINDS NINDS NNP cord-006870-f5w6fw6q 4806 3 encourages encourage VBZ cord-006870-f5w6fw6q 4806 4 the the DT cord-006870-f5w6fw6q 4806 5 use use NN cord-006870-f5w6fw6q 4806 6 of of IN cord-006870-f5w6fw6q 4806 7 CDEs cde NNS cord-006870-f5w6fw6q 4806 8 by by IN cord-006870-f5w6fw6q 4806 9 the the DT cord-006870-f5w6fw6q 4806 10 clinical clinical JJ cord-006870-f5w6fw6q 4806 11 research research NN cord-006870-f5w6fw6q 4806 12 community community NN cord-006870-f5w6fw6q 4806 13 in in IN cord-006870-f5w6fw6q 4806 14 order order NN cord-006870-f5w6fw6q 4806 15 to to TO cord-006870-f5w6fw6q 4806 16 standardize standardize VB cord-006870-f5w6fw6q 4806 17 the the DT cord-006870-f5w6fw6q 4806 18 collection collection NN cord-006870-f5w6fw6q 4806 19 of of IN cord-006870-f5w6fw6q 4806 20 research research NN cord-006870-f5w6fw6q 4806 21 data datum NNS cord-006870-f5w6fw6q 4806 22 across across IN cord-006870-f5w6fw6q 4806 23 studies study NNS cord-006870-f5w6fw6q 4806 24 . . . cord-006870-f5w6fw6q 4807 1 The the DT cord-006870-f5w6fw6q 4807 2 NINDS NINDS NNP cord-006870-f5w6fw6q 4807 3 CDEs cde NNS cord-006870-f5w6fw6q 4807 4 are be VBP cord-006870-f5w6fw6q 4807 5 a a DT cord-006870-f5w6fw6q 4807 6 continually continually RB cord-006870-f5w6fw6q 4807 7 evolving evolve VBG cord-006870-f5w6fw6q 4807 8 resource resource NN cord-006870-f5w6fw6q 4807 9 , , , cord-006870-f5w6fw6q 4807 10 requiring require VBG cord-006870-f5w6fw6q 4807 11 updates update NNS cord-006870-f5w6fw6q 4807 12 as as IN cord-006870-f5w6fw6q 4807 13 research research NN cord-006870-f5w6fw6q 4807 14 advancements advancement NNS cord-006870-f5w6fw6q 4807 15 indicate indicate VBP cord-006870-f5w6fw6q 4807 16 . . . cord-006870-f5w6fw6q 4808 1 These these DT cord-006870-f5w6fw6q 4808 2 newly newly RB cord-006870-f5w6fw6q 4808 3 developed develop VBN cord-006870-f5w6fw6q 4808 4 SAH SAH NNP cord-006870-f5w6fw6q 4808 5 CDEs cde NNS cord-006870-f5w6fw6q 4808 6 will will MD cord-006870-f5w6fw6q 4808 7 serve serve VB cord-006870-f5w6fw6q 4808 8 to to TO cord-006870-f5w6fw6q 4808 9 be be VB cord-006870-f5w6fw6q 4808 10 a a DT cord-006870-f5w6fw6q 4808 11 valuable valuable JJ cord-006870-f5w6fw6q 4808 12 starting starting NN cord-006870-f5w6fw6q 4808 13 point point NN cord-006870-f5w6fw6q 4808 14 for for IN cord-006870-f5w6fw6q 4808 15 researchers researcher NNS cord-006870-f5w6fw6q 4808 16 and and CC cord-006870-f5w6fw6q 4808 17 facilitate facilitate VBP cord-006870-f5w6fw6q 4808 18 streamlining streamline VBG cord-006870-f5w6fw6q 4808 19 and and CC cord-006870-f5w6fw6q 4808 20 sharing share VBG cord-006870-f5w6fw6q 4808 21 data datum NNS cord-006870-f5w6fw6q 4808 22 . . . cord-006870-f5w6fw6q 4809 1 Subarachnoid Subarachnoid NNP cord-006870-f5w6fw6q 4809 2 Hemorrhage Hemorrhage NNP cord-006870-f5w6fw6q 4809 3 ( ( -LRB- cord-006870-f5w6fw6q 4809 4 SAH SAH NNP cord-006870-f5w6fw6q 4809 5 ) ) -RRB- cord-006870-f5w6fw6q 4809 6 represents represent VBZ cord-006870-f5w6fw6q 4809 7 5 5 CD cord-006870-f5w6fw6q 4809 8 % % NN cord-006870-f5w6fw6q 4809 9 of of IN cord-006870-f5w6fw6q 4809 10 stroke stroke NN cord-006870-f5w6fw6q 4809 11 admissions admission NNS cord-006870-f5w6fw6q 4809 12 in in IN cord-006870-f5w6fw6q 4809 13 the the DT cord-006870-f5w6fw6q 4809 14 US US NNP cord-006870-f5w6fw6q 4809 15 . . . cord-006870-f5w6fw6q 4810 1 Aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 4810 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4810 3 represents represent VBZ cord-006870-f5w6fw6q 4810 4 the the DT cord-006870-f5w6fw6q 4810 5 most most RBS cord-006870-f5w6fw6q 4810 6 dangerous dangerous JJ cord-006870-f5w6fw6q 4810 7 etiology etiology NN cord-006870-f5w6fw6q 4810 8 , , , cord-006870-f5w6fw6q 4810 9 however however RB cord-006870-f5w6fw6q 4810 10 10 10 CD cord-006870-f5w6fw6q 4810 11 - - SYM cord-006870-f5w6fw6q 4810 12 15 15 CD cord-006870-f5w6fw6q 4810 13 % % NN cord-006870-f5w6fw6q 4810 14 of of IN cord-006870-f5w6fw6q 4810 15 SAH SAH NNP cord-006870-f5w6fw6q 4810 16 have have VBP cord-006870-f5w6fw6q 4810 17 negative negative JJ cord-006870-f5w6fw6q 4810 18 digital digital JJ cord-006870-f5w6fw6q 4810 19 subtraction subtraction NN cord-006870-f5w6fw6q 4810 20 angiography angiography NN cord-006870-f5w6fw6q 4810 21 ( ( -LRB- cord-006870-f5w6fw6q 4810 22 DSA DSA NNP cord-006870-f5w6fw6q 4810 23 ) ) -RRB- cord-006870-f5w6fw6q 4810 24 . . . cord-006870-f5w6fw6q 4811 1 There there EX cord-006870-f5w6fw6q 4811 2 is be VBZ cord-006870-f5w6fw6q 4811 3 variation variation NN cord-006870-f5w6fw6q 4811 4 in in IN cord-006870-f5w6fw6q 4811 5 practice practice NN cord-006870-f5w6fw6q 4811 6 with with IN cord-006870-f5w6fw6q 4811 7 regards regard NNS cord-006870-f5w6fw6q 4811 8 to to TO cord-006870-f5w6fw6q 4811 9 repeat repeat VB cord-006870-f5w6fw6q 4811 10 diagnostic diagnostic JJ cord-006870-f5w6fw6q 4811 11 studies study NNS cord-006870-f5w6fw6q 4811 12 and and CC cord-006870-f5w6fw6q 4811 13 timing timing NN cord-006870-f5w6fw6q 4811 14 of of IN cord-006870-f5w6fw6q 4811 15 such such JJ cord-006870-f5w6fw6q 4811 16 studies study NNS cord-006870-f5w6fw6q 4811 17 . . . cord-006870-f5w6fw6q 4812 1 It -PRON- PRP cord-006870-f5w6fw6q 4812 2 is be VBZ cord-006870-f5w6fw6q 4812 3 not not RB cord-006870-f5w6fw6q 4812 4 uncommon uncommon JJ cord-006870-f5w6fw6q 4812 5 to to TO cord-006870-f5w6fw6q 4812 6 repeat repeat VB cord-006870-f5w6fw6q 4812 7 DSA DSA NNP cord-006870-f5w6fw6q 4812 8 in in IN cord-006870-f5w6fw6q 4812 9 7 7 CD cord-006870-f5w6fw6q 4812 10 - - SYM cord-006870-f5w6fw6q 4812 11 10 10 CD cord-006870-f5w6fw6q 4812 12 days day NNS cord-006870-f5w6fw6q 4812 13 of of IN cord-006870-f5w6fw6q 4812 14 the the DT cord-006870-f5w6fw6q 4812 15 initial initial JJ cord-006870-f5w6fw6q 4812 16 assessments assessment NNS cord-006870-f5w6fw6q 4812 17 . . . cord-006870-f5w6fw6q 4813 1 This this DT cord-006870-f5w6fw6q 4813 2 study study NN cord-006870-f5w6fw6q 4813 3 aims aim VBZ cord-006870-f5w6fw6q 4813 4 to to TO cord-006870-f5w6fw6q 4813 5 describe describe VB cord-006870-f5w6fw6q 4813 6 the the DT cord-006870-f5w6fw6q 4813 7 costs cost NNS cord-006870-f5w6fw6q 4813 8 associated associate VBN cord-006870-f5w6fw6q 4813 9 with with IN cord-006870-f5w6fw6q 4813 10 prolonged prolong VBN cord-006870-f5w6fw6q 4813 11 ICU ICU NNP cord-006870-f5w6fw6q 4813 12 stay stay NN cord-006870-f5w6fw6q 4813 13 and and CC cord-006870-f5w6fw6q 4813 14 repeat repeat VB cord-006870-f5w6fw6q 4813 15 diagnostic diagnostic JJ cord-006870-f5w6fw6q 4813 16 studies study NNS cord-006870-f5w6fw6q 4813 17 this this DT cord-006870-f5w6fw6q 4813 18 patient patient JJ cord-006870-f5w6fw6q 4813 19 cohort cohort NN cord-006870-f5w6fw6q 4813 20 . . . cord-006870-f5w6fw6q 4814 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 4814 2 review review NN cord-006870-f5w6fw6q 4814 3 of of IN cord-006870-f5w6fw6q 4814 4 all all DT cord-006870-f5w6fw6q 4814 5 patients patient NNS cord-006870-f5w6fw6q 4814 6 admitted admit VBN cord-006870-f5w6fw6q 4814 7 for for IN cord-006870-f5w6fw6q 4814 8 spontaneous spontaneous JJ cord-006870-f5w6fw6q 4814 9 SAH sah NN cord-006870-f5w6fw6q 4814 10 between between IN cord-006870-f5w6fw6q 4814 11 January January NNP cord-006870-f5w6fw6q 4814 12 2011 2011 CD cord-006870-f5w6fw6q 4814 13 and and CC cord-006870-f5w6fw6q 4814 14 April April NNP cord-006870-f5w6fw6q 4814 15 2017 2017 CD cord-006870-f5w6fw6q 4814 16 at at IN cord-006870-f5w6fw6q 4814 17 our -PRON- PRP$ cord-006870-f5w6fw6q 4814 18 single single JJ cord-006870-f5w6fw6q 4814 19 institution institution NN cord-006870-f5w6fw6q 4814 20 . . . cord-006870-f5w6fw6q 4815 1 Patients patient NNS cord-006870-f5w6fw6q 4815 2 with with IN cord-006870-f5w6fw6q 4815 3 at at RB cord-006870-f5w6fw6q 4815 4 least least RBS cord-006870-f5w6fw6q 4815 5 one one CD cord-006870-f5w6fw6q 4815 6 negative negative JJ cord-006870-f5w6fw6q 4815 7 initial initial JJ cord-006870-f5w6fw6q 4815 8 angiogram angiogram NN cord-006870-f5w6fw6q 4815 9 for for IN cord-006870-f5w6fw6q 4815 10 suspected suspect VBN cord-006870-f5w6fw6q 4815 11 spontaneous spontaneous JJ cord-006870-f5w6fw6q 4815 12 SAH SAH NNP cord-006870-f5w6fw6q 4815 13 were be VBD cord-006870-f5w6fw6q 4815 14 included include VBN cord-006870-f5w6fw6q 4815 15 . . . cord-006870-f5w6fw6q 4816 1 Patients patient NNS cord-006870-f5w6fw6q 4816 2 were be VBD cord-006870-f5w6fw6q 4816 3 categorized categorize VBN cord-006870-f5w6fw6q 4816 4 into into IN cord-006870-f5w6fw6q 4816 5 diffuse diffuse JJ cord-006870-f5w6fw6q 4816 6 patterns pattern NNS cord-006870-f5w6fw6q 4816 7 of of IN cord-006870-f5w6fw6q 4816 8 SAH SAH NNP cord-006870-f5w6fw6q 4816 9 and and CC cord-006870-f5w6fw6q 4816 10 nondiffuse nondiffuse NNP cord-006870-f5w6fw6q 4816 11 . . . cord-006870-f5w6fw6q 4817 1 Cost cost NN cord-006870-f5w6fw6q 4817 2 estimates estimate NNS cord-006870-f5w6fw6q 4817 3 were be VBD cord-006870-f5w6fw6q 4817 4 based base VBN cord-006870-f5w6fw6q 4817 5 on on IN cord-006870-f5w6fw6q 4817 6 standard standard JJ cord-006870-f5w6fw6q 4817 7 costs cost NNS cord-006870-f5w6fw6q 4817 8 as as IN cord-006870-f5w6fw6q 4817 9 provided provide VBN cord-006870-f5w6fw6q 4817 10 by by IN cord-006870-f5w6fw6q 4817 11 our -PRON- PRP$ cord-006870-f5w6fw6q 4817 12 financial financial JJ cord-006870-f5w6fw6q 4817 13 department department NN cord-006870-f5w6fw6q 4817 14 and and CC cord-006870-f5w6fw6q 4817 15 CDC CDC NNP cord-006870-f5w6fw6q 4817 16 estimates estimate NNS cord-006870-f5w6fw6q 4817 17 for for IN cord-006870-f5w6fw6q 4817 18 costs cost NNS cord-006870-f5w6fw6q 4817 19 of of IN cord-006870-f5w6fw6q 4817 20 hospital hospital NN cord-006870-f5w6fw6q 4817 21 acquired acquire VBN cord-006870-f5w6fw6q 4817 22 infections infection NNS cord-006870-f5w6fw6q 4817 23 . . . cord-006870-f5w6fw6q 4818 1 One one CD cord-006870-f5w6fw6q 4818 2 hundred hundred CD cord-006870-f5w6fw6q 4818 3 fifty fifty CD cord-006870-f5w6fw6q 4818 4 - - HYPH cord-006870-f5w6fw6q 4818 5 four four CD cord-006870-f5w6fw6q 4818 6 patients patient NNS cord-006870-f5w6fw6q 4818 7 were be VBD cord-006870-f5w6fw6q 4818 8 identified identify VBN cord-006870-f5w6fw6q 4818 9 with with IN cord-006870-f5w6fw6q 4818 10 initial initial JJ cord-006870-f5w6fw6q 4818 11 negative negative JJ cord-006870-f5w6fw6q 4818 12 DSA DSA NNP cord-006870-f5w6fw6q 4818 13 . . . cord-006870-f5w6fw6q 4819 1 Second second JJ cord-006870-f5w6fw6q 4819 2 angiograms angiogram NNS cord-006870-f5w6fw6q 4819 3 were be VBD cord-006870-f5w6fw6q 4819 4 performed perform VBN cord-006870-f5w6fw6q 4819 5 in in IN cord-006870-f5w6fw6q 4819 6 81 81 CD cord-006870-f5w6fw6q 4819 7 % % NN cord-006870-f5w6fw6q 4819 8 of of IN cord-006870-f5w6fw6q 4819 9 patients patient NNS cord-006870-f5w6fw6q 4819 10 , , , cord-006870-f5w6fw6q 4819 11 and and CC cord-006870-f5w6fw6q 4819 12 potentially potentially RB cord-006870-f5w6fw6q 4819 13 positive positive JJ cord-006870-f5w6fw6q 4819 14 causal causal JJ cord-006870-f5w6fw6q 4819 15 findings finding NNS cord-006870-f5w6fw6q 4819 16 in in IN cord-006870-f5w6fw6q 4819 17 18/125 18/125 CD cord-006870-f5w6fw6q 4819 18 ( ( -LRB- cord-006870-f5w6fw6q 4819 19 14.4 14.4 CD cord-006870-f5w6fw6q 4819 20 % % NN cord-006870-f5w6fw6q 4819 21 ) ) -RRB- cord-006870-f5w6fw6q 4819 22 . . . cord-006870-f5w6fw6q 4820 1 ICU ICU NNP cord-006870-f5w6fw6q 4820 2 LOS LOS NNP cord-006870-f5w6fw6q 4820 3 for for IN cord-006870-f5w6fw6q 4820 4 angiogram angiogram NN cord-006870-f5w6fw6q 4820 5 negative negative JJ cord-006870-f5w6fw6q 4820 6 diffuse diffuse NN cord-006870-f5w6fw6q 4820 7 SAH SAH NNP cord-006870-f5w6fw6q 4820 8 and and CC cord-006870-f5w6fw6q 4820 9 non non JJ cord-006870-f5w6fw6q 4820 10 - - JJ cord-006870-f5w6fw6q 4820 11 diffuse diffuse JJ cord-006870-f5w6fw6q 4820 12 were be VBD cord-006870-f5w6fw6q 4820 13 10.1 10.1 CD cord-006870-f5w6fw6q 4820 14 and and CC cord-006870-f5w6fw6q 4820 15 6.5 6.5 CD cord-006870-f5w6fw6q 4820 16 days day NNS cord-006870-f5w6fw6q 4820 17 respectively respectively RB cord-006870-f5w6fw6q 4820 18 . . . cord-006870-f5w6fw6q 4821 1 Other other JJ cord-006870-f5w6fw6q 4821 2 indications indication NNS cord-006870-f5w6fw6q 4821 3 for for IN cord-006870-f5w6fw6q 4821 4 ICU ICU NNP cord-006870-f5w6fw6q 4821 5 stay stay NN cord-006870-f5w6fw6q 4821 6 included include VBN cord-006870-f5w6fw6q 4821 7 vasospasm vasospasm NN cord-006870-f5w6fw6q 4821 8 ( ( -LRB- cord-006870-f5w6fw6q 4821 9 8.5 8.5 CD cord-006870-f5w6fw6q 4821 10 % % NN cord-006870-f5w6fw6q 4821 11 ) ) -RRB- cord-006870-f5w6fw6q 4821 12 , , , cord-006870-f5w6fw6q 4821 13 EVD EVD NNP cord-006870-f5w6fw6q 4821 14 placement placement NN cord-006870-f5w6fw6q 4821 15 ( ( -LRB- cord-006870-f5w6fw6q 4821 16 30.8 30.8 CD cord-006870-f5w6fw6q 4821 17 % % NN cord-006870-f5w6fw6q 4821 18 ) ) -RRB- cord-006870-f5w6fw6q 4821 19 , , , cord-006870-f5w6fw6q 4821 20 and and CC cord-006870-f5w6fw6q 4821 21 Intubation Intubation NNP cord-006870-f5w6fw6q 4821 22 ( ( -LRB- cord-006870-f5w6fw6q 4821 23 22 22 CD cord-006870-f5w6fw6q 4821 24 % % NN cord-006870-f5w6fw6q 4821 25 ) ) -RRB- cord-006870-f5w6fw6q 4821 26 . . . cord-006870-f5w6fw6q 4822 1 The the DT cord-006870-f5w6fw6q 4822 2 excess excess JJ cord-006870-f5w6fw6q 4822 3 cost cost NN cord-006870-f5w6fw6q 4822 4 estimates estimate NNS cord-006870-f5w6fw6q 4822 5 per per IN cord-006870-f5w6fw6q 4822 6 patient patient NN cord-006870-f5w6fw6q 4822 7 for for IN cord-006870-f5w6fw6q 4822 8 angiogram angiogram JJ cord-006870-f5w6fw6q 4822 9 negative negative JJ cord-006870-f5w6fw6q 4822 10 diffuse diffuse NN cord-006870-f5w6fw6q 4822 11 and and CC cord-006870-f5w6fw6q 4822 12 non non JJ cord-006870-f5w6fw6q 4822 13 - - JJ cord-006870-f5w6fw6q 4822 14 diffuse diffuse JJ cord-006870-f5w6fw6q 4823 1 SAH SAH NNP cord-006870-f5w6fw6q 4823 2 were be VBD cord-006870-f5w6fw6q 4823 3 $ $ $ cord-006870-f5w6fw6q 4823 4 71,567 71,567 CD cord-006870-f5w6fw6q 4823 5 and and CC cord-006870-f5w6fw6q 4823 6 $ $ $ cord-006870-f5w6fw6q 4823 7 52,843 52,843 CD cord-006870-f5w6fw6q 4823 8 respectively respectively RB cord-006870-f5w6fw6q 4823 9 . . . cord-006870-f5w6fw6q 4824 1 Hospital hospital NN cord-006870-f5w6fw6q 4824 2 acquired acquire VBD cord-006870-f5w6fw6q 4824 3 complications complication NNS cord-006870-f5w6fw6q 4824 4 were be VBD cord-006870-f5w6fw6q 4824 5 an an DT cord-006870-f5w6fw6q 4824 6 additional additional JJ cord-006870-f5w6fw6q 4824 7 total total JJ cord-006870-f5w6fw6q 4824 8 $ $ $ cord-006870-f5w6fw6q 4824 9 57,422 57,422 CD cord-006870-f5w6fw6q 4824 10 for for IN cord-006870-f5w6fw6q 4824 11 the the DT cord-006870-f5w6fw6q 4824 12 cohort cohort NN cord-006870-f5w6fw6q 4824 13 . . . cord-006870-f5w6fw6q 4825 1 This this DT cord-006870-f5w6fw6q 4825 2 is be VBZ cord-006870-f5w6fw6q 4825 3 the the DT cord-006870-f5w6fw6q 4825 4 first first JJ cord-006870-f5w6fw6q 4825 5 study study NN cord-006870-f5w6fw6q 4825 6 to to IN cord-006870-f5w6fw6q 4825 7 our -PRON- PRP$ cord-006870-f5w6fw6q 4825 8 knowledge knowledge NN cord-006870-f5w6fw6q 4825 9 attempting attempt VBG cord-006870-f5w6fw6q 4825 10 a a DT cord-006870-f5w6fw6q 4825 11 cost cost NN cord-006870-f5w6fw6q 4825 12 analysis analysis NN cord-006870-f5w6fw6q 4825 13 of of IN cord-006870-f5w6fw6q 4825 14 the the DT cord-006870-f5w6fw6q 4825 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 4825 16 and and CC cord-006870-f5w6fw6q 4825 17 management management NN cord-006870-f5w6fw6q 4825 18 of of IN cord-006870-f5w6fw6q 4825 19 patients patient NNS cord-006870-f5w6fw6q 4825 20 with with IN cord-006870-f5w6fw6q 4825 21 angiogram angiogram NN cord-006870-f5w6fw6q 4825 22 negative negative JJ cord-006870-f5w6fw6q 4825 23 SAH SAH NNP cord-006870-f5w6fw6q 4825 24 . . . cord-006870-f5w6fw6q 4826 1 We -PRON- PRP cord-006870-f5w6fw6q 4826 2 had have VBD cord-006870-f5w6fw6q 4826 3 a a DT cord-006870-f5w6fw6q 4826 4 high high JJ cord-006870-f5w6fw6q 4826 5 frequency frequency NN cord-006870-f5w6fw6q 4826 6 of of IN cord-006870-f5w6fw6q 4826 7 patients patient NNS cord-006870-f5w6fw6q 4826 8 requiring require VBG cord-006870-f5w6fw6q 4826 9 ICU ICU NNP cord-006870-f5w6fw6q 4826 10 admission admission NN cord-006870-f5w6fw6q 4826 11 for for IN cord-006870-f5w6fw6q 4826 12 other other JJ cord-006870-f5w6fw6q 4826 13 indications indication NNS cord-006870-f5w6fw6q 4826 14 , , , cord-006870-f5w6fw6q 4826 15 which which WDT cord-006870-f5w6fw6q 4826 16 should should MD cord-006870-f5w6fw6q 4826 17 continue continue VB cord-006870-f5w6fw6q 4826 18 to to TO cord-006870-f5w6fw6q 4826 19 dictate dictate VB cord-006870-f5w6fw6q 4826 20 the the DT cord-006870-f5w6fw6q 4826 21 level level NN cord-006870-f5w6fw6q 4826 22 of of IN cord-006870-f5w6fw6q 4826 23 care care NN cord-006870-f5w6fw6q 4826 24 . . . cord-006870-f5w6fw6q 4827 1 However however RB cord-006870-f5w6fw6q 4827 2 , , , cord-006870-f5w6fw6q 4827 3 there there EX cord-006870-f5w6fw6q 4827 4 may may MD cord-006870-f5w6fw6q 4827 5 be be VB cord-006870-f5w6fw6q 4827 6 a a DT cord-006870-f5w6fw6q 4827 7 cohort cohort NN cord-006870-f5w6fw6q 4827 8 of of IN cord-006870-f5w6fw6q 4827 9 lower low JJR cord-006870-f5w6fw6q 4827 10 risk risk NN cord-006870-f5w6fw6q 4827 11 patients patient NNS cord-006870-f5w6fw6q 4827 12 in in IN cord-006870-f5w6fw6q 4827 13 which which WDT cord-006870-f5w6fw6q 4827 14 de de NN cord-006870-f5w6fw6q 4827 15 - - NN cord-006870-f5w6fw6q 4827 16 escalation escalation NN cord-006870-f5w6fw6q 4827 17 would would MD cord-006870-f5w6fw6q 4827 18 not not RB cord-006870-f5w6fw6q 4827 19 harm harm VB cord-006870-f5w6fw6q 4827 20 , , , cord-006870-f5w6fw6q 4827 21 and and CC cord-006870-f5w6fw6q 4827 22 be be VB cord-006870-f5w6fw6q 4827 23 of of IN cord-006870-f5w6fw6q 4827 24 benefit benefit NN cord-006870-f5w6fw6q 4827 25 in in IN cord-006870-f5w6fw6q 4827 26 the the DT cord-006870-f5w6fw6q 4827 27 reduction reduction NN cord-006870-f5w6fw6q 4827 28 of of IN cord-006870-f5w6fw6q 4827 29 morbidity morbidity NN cord-006870-f5w6fw6q 4827 30 and and CC cord-006870-f5w6fw6q 4827 31 cost cost NN cord-006870-f5w6fw6q 4827 32 . . . cord-006870-f5w6fw6q 4828 1 Purpose purpose NN cord-006870-f5w6fw6q 4828 2 : : : cord-006870-f5w6fw6q 4828 3 To to TO cord-006870-f5w6fw6q 4828 4 evaluate evaluate VB cord-006870-f5w6fw6q 4828 5 the the DT cord-006870-f5w6fw6q 4828 6 feasibility feasibility NN cord-006870-f5w6fw6q 4828 7 and and CC cord-006870-f5w6fw6q 4828 8 potential potential JJ cord-006870-f5w6fw6q 4828 9 role role NN cord-006870-f5w6fw6q 4828 10 of of IN cord-006870-f5w6fw6q 4828 11 bedside bedside NN cord-006870-f5w6fw6q 4828 12 optical optical JJ cord-006870-f5w6fw6q 4828 13 coherence coherence NN cord-006870-f5w6fw6q 4828 14 tomography tomography NN cord-006870-f5w6fw6q 4828 15 ( ( -LRB- cord-006870-f5w6fw6q 4828 16 OCT OCT NNP cord-006870-f5w6fw6q 4828 17 ) ) -RRB- cord-006870-f5w6fw6q 4828 18 as as IN cord-006870-f5w6fw6q 4828 19 a a DT cord-006870-f5w6fw6q 4828 20 diagnostic diagnostic JJ cord-006870-f5w6fw6q 4828 21 protocol protocol NN cord-006870-f5w6fw6q 4828 22 in in IN cord-006870-f5w6fw6q 4828 23 Terson Terson NNP cord-006870-f5w6fw6q 4828 24 's 's POS cord-006870-f5w6fw6q 4828 25 Syndrome Syndrome NNP cord-006870-f5w6fw6q 4828 26 ( ( -LRB- cord-006870-f5w6fw6q 4828 27 TS TS NNP cord-006870-f5w6fw6q 4828 28 ) ) -RRB- cord-006870-f5w6fw6q 4828 29 in in IN cord-006870-f5w6fw6q 4828 30 patients patient NNS cord-006870-f5w6fw6q 4828 31 with with IN cord-006870-f5w6fw6q 4828 32 acute acute JJ cord-006870-f5w6fw6q 4828 33 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4828 34 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4828 35 ( ( -LRB- cord-006870-f5w6fw6q 4828 36 aSAH asah JJ cord-006870-f5w6fw6q 4828 37 ) ) -RRB- cord-006870-f5w6fw6q 4828 38 . . . cord-006870-f5w6fw6q 4829 1 Background background NN cord-006870-f5w6fw6q 4829 2 : : : cord-006870-f5w6fw6q 4830 1 10 10 CD cord-006870-f5w6fw6q 4830 2 % % NN cord-006870-f5w6fw6q 4830 3 of of IN cord-006870-f5w6fw6q 4830 4 SAH SAH NNP cord-006870-f5w6fw6q 4830 5 patients patient NNS cord-006870-f5w6fw6q 4830 6 become become VBP cord-006870-f5w6fw6q 4830 7 permanently permanently RB cord-006870-f5w6fw6q 4830 8 legally legally RB cord-006870-f5w6fw6q 4830 9 blind blind JJ cord-006870-f5w6fw6q 4830 10 . . . cord-006870-f5w6fw6q 4831 1 The the DT cord-006870-f5w6fw6q 4831 2 average average JJ cord-006870-f5w6fw6q 4831 3 cost cost NN cord-006870-f5w6fw6q 4831 4 of of IN cord-006870-f5w6fw6q 4831 5 lifetime lifetime NN cord-006870-f5w6fw6q 4831 6 support support NN cord-006870-f5w6fw6q 4831 7 and and CC cord-006870-f5w6fw6q 4831 8 unpaid unpaid JJ cord-006870-f5w6fw6q 4831 9 taxes taxis NNS cord-006870-f5w6fw6q 4831 10 for for IN cord-006870-f5w6fw6q 4831 11 each each DT cord-006870-f5w6fw6q 4831 12 blind blind JJ cord-006870-f5w6fw6q 4831 13 person person NN cord-006870-f5w6fw6q 4831 14 is be VBZ cord-006870-f5w6fw6q 4831 15 approximately approximately RB cord-006870-f5w6fw6q 4831 16 $ $ $ cord-006870-f5w6fw6q 4831 17 900,000 900,000 CD cord-006870-f5w6fw6q 4831 18 . . . cord-006870-f5w6fw6q 4832 1 TS TS NNP cord-006870-f5w6fw6q 4832 2 presents present VBZ cord-006870-f5w6fw6q 4832 3 as as IN cord-006870-f5w6fw6q 4832 4 ocular ocular JJ cord-006870-f5w6fw6q 4832 5 bleeding bleeding NN cord-006870-f5w6fw6q 4832 6 commonly commonly RB cord-006870-f5w6fw6q 4832 7 associated associate VBN cord-006870-f5w6fw6q 4832 8 with with IN cord-006870-f5w6fw6q 4832 9 aSAH asah JJ cord-006870-f5w6fw6q 4832 10 . . . cord-006870-f5w6fw6q 4833 1 It -PRON- PRP cord-006870-f5w6fw6q 4833 2 can can MD cord-006870-f5w6fw6q 4833 3 be be VB cord-006870-f5w6fw6q 4833 4 diagnosed diagnose VBN cord-006870-f5w6fw6q 4833 5 by by IN cord-006870-f5w6fw6q 4833 6 fundoscopy fundoscopy NNP cord-006870-f5w6fw6q 4833 7 , , , cord-006870-f5w6fw6q 4833 8 yet yet CC cord-006870-f5w6fw6q 4833 9 retinal retinal JJ cord-006870-f5w6fw6q 4833 10 haemorrhages haemorrhage NNS cord-006870-f5w6fw6q 4833 11 , , , cord-006870-f5w6fw6q 4833 12 detachments detachment NNS cord-006870-f5w6fw6q 4833 13 and and CC cord-006870-f5w6fw6q 4833 14 macular macular JJ cord-006870-f5w6fw6q 4833 15 holes hole NNS cord-006870-f5w6fw6q 4833 16 may may MD cord-006870-f5w6fw6q 4833 17 be be VB cord-006870-f5w6fw6q 4833 18 undetected undetected JJ cord-006870-f5w6fw6q 4833 19 . . . cord-006870-f5w6fw6q 4834 1 Early early JJ cord-006870-f5w6fw6q 4834 2 TS ts NN cord-006870-f5w6fw6q 4834 3 identification identification NN cord-006870-f5w6fw6q 4834 4 is be VBZ cord-006870-f5w6fw6q 4834 5 critical critical JJ cord-006870-f5w6fw6q 4834 6 since since IN cord-006870-f5w6fw6q 4834 7 untreated untreated JJ cord-006870-f5w6fw6q 4834 8 it -PRON- PRP cord-006870-f5w6fw6q 4834 9 may may MD cord-006870-f5w6fw6q 4834 10 lead lead VB cord-006870-f5w6fw6q 4834 11 to to IN cord-006870-f5w6fw6q 4834 12 legal legal JJ cord-006870-f5w6fw6q 4834 13 blindness blindness NN cord-006870-f5w6fw6q 4834 14 , , , cord-006870-f5w6fw6q 4834 15 limit limit VB cord-006870-f5w6fw6q 4834 16 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 4834 17 and and CC cord-006870-f5w6fw6q 4834 18 impair impair VB cord-006870-f5w6fw6q 4834 19 quality quality NN cord-006870-f5w6fw6q 4834 20 of of IN cord-006870-f5w6fw6q 4834 21 life life NN cord-006870-f5w6fw6q 4834 22 . . . cord-006870-f5w6fw6q 4835 1 Pilot pilot NN cord-006870-f5w6fw6q 4835 2 study study NN cord-006870-f5w6fw6q 4835 3 : : : cord-006870-f5w6fw6q 4835 4 31 31 CD cord-006870-f5w6fw6q 4835 5 SAH SAH NNP cord-006870-f5w6fw6q 4835 6 patients patient NNS cord-006870-f5w6fw6q 4835 7 were be VBD cord-006870-f5w6fw6q 4835 8 screened screen VBN cord-006870-f5w6fw6q 4835 9 for for IN cord-006870-f5w6fw6q 4835 10 TS TS NNP cord-006870-f5w6fw6q 4835 11 with with IN cord-006870-f5w6fw6q 4835 12 dilated dilated JJ cord-006870-f5w6fw6q 4835 13 fundoscopy fundoscopy NN cord-006870-f5w6fw6q 4835 14 and and CC cord-006870-f5w6fw6q 4835 15 then then RB cord-006870-f5w6fw6q 4835 16 with with IN cord-006870-f5w6fw6q 4835 17 OCT OCT NNP cord-006870-f5w6fw6q 4835 18 . . . cord-006870-f5w6fw6q 4836 1 Mood mood NN cord-006870-f5w6fw6q 4836 2 assessments assessment NNS cord-006870-f5w6fw6q 4836 3 ( ( -LRB- cord-006870-f5w6fw6q 4836 4 PHQ-9 PHQ-9 NNP cord-006870-f5w6fw6q 4836 5 , , , cord-006870-f5w6fw6q 4836 6 HDS HDS NNP cord-006870-f5w6fw6q 4836 7 ) ) -RRB- cord-006870-f5w6fw6q 4836 8 , , , cord-006870-f5w6fw6q 4836 9 quality quality NN cord-006870-f5w6fw6q 4836 10 of of IN cord-006870-f5w6fw6q 4836 11 life life NN cord-006870-f5w6fw6q 4836 12 measures measure NNS cord-006870-f5w6fw6q 4836 13 ( ( -LRB- cord-006870-f5w6fw6q 4836 14 NIH NIH NNP cord-006870-f5w6fw6q 4836 15 - - HYPH cord-006870-f5w6fw6q 4836 16 PROMIS PROMIS NNP cord-006870-f5w6fw6q 4836 17 ) ) -RRB- cord-006870-f5w6fw6q 4836 18 and and CC cord-006870-f5w6fw6q 4836 19 subjective subjective JJ cord-006870-f5w6fw6q 4836 20 visual visual JJ cord-006870-f5w6fw6q 4836 21 function function NN cord-006870-f5w6fw6q 4836 22 scales scale NNS cord-006870-f5w6fw6q 4836 23 ( ( -LRB- cord-006870-f5w6fw6q 4836 24 VFQ-25 VFQ-25 NNP cord-006870-f5w6fw6q 4836 25 ) ) -RRB- cord-006870-f5w6fw6q 4836 26 were be VBD cord-006870-f5w6fw6q 4836 27 performed perform VBN cord-006870-f5w6fw6q 4836 28 . . . cord-006870-f5w6fw6q 4837 1 There there EX cord-006870-f5w6fw6q 4837 2 was be VBD cord-006870-f5w6fw6q 4837 3 a a DT cord-006870-f5w6fw6q 4837 4 22.6 22.6 CD cord-006870-f5w6fw6q 4837 5 % % NN cord-006870-f5w6fw6q 4837 6 ( ( -LRB- cord-006870-f5w6fw6q 4837 7 n=7 n=7 NN cord-006870-f5w6fw6q 4837 8 ) ) -RRB- cord-006870-f5w6fw6q 4837 9 incidence incidence NN cord-006870-f5w6fw6q 4837 10 of of IN cord-006870-f5w6fw6q 4837 11 TS TS NNP cord-006870-f5w6fw6q 4837 12 . . . cord-006870-f5w6fw6q 4838 1 Dilated dilated JJ cord-006870-f5w6fw6q 4838 2 retinal retinal JJ cord-006870-f5w6fw6q 4838 3 fundoscopy fundoscopy NN cord-006870-f5w6fw6q 4838 4 significantly significantly RB cord-006870-f5w6fw6q 4838 5 failed fail VBD cord-006870-f5w6fw6q 4838 6 to to TO cord-006870-f5w6fw6q 4838 7 detect detect VB cord-006870-f5w6fw6q 4838 8 TS TS NNP cord-006870-f5w6fw6q 4838 9 ( ( -LRB- cord-006870-f5w6fw6q 4838 10 n=4 n=4 NNS cord-006870-f5w6fw6q 4838 11 , , , cord-006870-f5w6fw6q 4838 12 57.1 57.1 CD cord-006870-f5w6fw6q 4838 13 % % NN cord-006870-f5w6fw6q 4838 14 missed miss VBN cord-006870-f5w6fw6q 4838 15 cases case NNS cord-006870-f5w6fw6q 4838 16 ) ) -RRB- cord-006870-f5w6fw6q 4838 17 . . . cord-006870-f5w6fw6q 4839 1 IVH IVH NNP cord-006870-f5w6fw6q 4839 2 was be VBD cord-006870-f5w6fw6q 4839 3 significantly significantly RB cord-006870-f5w6fw6q 4839 4 more more JJR cord-006870-f5w6fw6q 4839 5 in in IN cord-006870-f5w6fw6q 4839 6 TS TS NNP cord-006870-f5w6fw6q 4839 7 ( ( -LRB- cord-006870-f5w6fw6q 4839 8 85.7 85.7 CD cord-006870-f5w6fw6q 4839 9 % % NN cord-006870-f5w6fw6q 4839 10 vs. vs. IN cord-006870-f5w6fw6q 4839 11 25 25 CD cord-006870-f5w6fw6q 4839 12 % % NN cord-006870-f5w6fw6q 4839 13 ) ) -RRB- cord-006870-f5w6fw6q 4839 14 . . . cord-006870-f5w6fw6q 4840 1 No no DT cord-006870-f5w6fw6q 4840 2 participants participant NNS cord-006870-f5w6fw6q 4840 3 experienced experience VBD cord-006870-f5w6fw6q 4840 4 any any DT cord-006870-f5w6fw6q 4840 5 complications complication NNS cord-006870-f5w6fw6q 4840 6 from from IN cord-006870-f5w6fw6q 4840 7 OCT OCT NNP cord-006870-f5w6fw6q 4840 8 examinations examination NNS cord-006870-f5w6fw6q 4840 9 . . . cord-006870-f5w6fw6q 4841 1 Neither neither CC cord-006870-f5w6fw6q 4841 2 decreased decrease VBD cord-006870-f5w6fw6q 4841 3 quality quality NN cord-006870-f5w6fw6q 4841 4 of of IN cord-006870-f5w6fw6q 4841 5 life life NN cord-006870-f5w6fw6q 4841 6 visual visual JJ cord-006870-f5w6fw6q 4841 7 scores score NNS cord-006870-f5w6fw6q 4841 8 nor nor CC cord-006870-f5w6fw6q 4841 9 a a DT cord-006870-f5w6fw6q 4841 10 depressed depressed JJ cord-006870-f5w6fw6q 4841 11 mood mood NN cord-006870-f5w6fw6q 4841 12 correlated correlate VBN cord-006870-f5w6fw6q 4841 13 with with IN cord-006870-f5w6fw6q 4841 14 objective objective JJ cord-006870-f5w6fw6q 4841 15 OCT OCT NNP cord-006870-f5w6fw6q 4841 16 pathological pathological JJ cord-006870-f5w6fw6q 4841 17 findings finding NNS cord-006870-f5w6fw6q 4841 18 at at IN cord-006870-f5w6fw6q 4841 19 6 6 CD cord-006870-f5w6fw6q 4841 20 weeks week NNS cord-006870-f5w6fw6q 4841 21 follow follow NN cord-006870-f5w6fw6q 4841 22 - - HYPH cord-006870-f5w6fw6q 4841 23 up up NN cord-006870-f5w6fw6q 4841 24 after after IN cord-006870-f5w6fw6q 4841 25 discharge discharge NN cord-006870-f5w6fw6q 4841 26 . . . cord-006870-f5w6fw6q 4842 1 There there EX cord-006870-f5w6fw6q 4842 2 were be VBD cord-006870-f5w6fw6q 4842 3 no no DT cord-006870-f5w6fw6q 4842 4 significant significant JJ cord-006870-f5w6fw6q 4842 5 mood mood NN cord-006870-f5w6fw6q 4842 6 differences difference NNS cord-006870-f5w6fw6q 4842 7 between between IN cord-006870-f5w6fw6q 4842 8 TS TS NNP cord-006870-f5w6fw6q 4842 9 cases case NNS cord-006870-f5w6fw6q 4842 10 and and CC cord-006870-f5w6fw6q 4842 11 controls control NNS cord-006870-f5w6fw6q 4842 12 . . . cord-006870-f5w6fw6q 4843 1 OCT OCT NNP cord-006870-f5w6fw6q 4843 2 is be VBZ cord-006870-f5w6fw6q 4843 3 the the DT cord-006870-f5w6fw6q 4843 4 gold gold NN cord-006870-f5w6fw6q 4843 5 - - HYPH cord-006870-f5w6fw6q 4843 6 standard standard NN cord-006870-f5w6fw6q 4843 7 in in IN cord-006870-f5w6fw6q 4843 8 retinal retinal JJ cord-006870-f5w6fw6q 4843 9 disease disease NN cord-006870-f5w6fw6q 4843 10 diagnosis diagnosis NN cord-006870-f5w6fw6q 4843 11 . . . cord-006870-f5w6fw6q 4844 1 This this DT cord-006870-f5w6fw6q 4844 2 pilot pilot NN cord-006870-f5w6fw6q 4844 3 study study NN cord-006870-f5w6fw6q 4844 4 showcases showcase VBZ cord-006870-f5w6fw6q 4844 5 its -PRON- PRP$ cord-006870-f5w6fw6q 4844 6 bedside bedside NN cord-006870-f5w6fw6q 4844 7 feasibility feasibility NN cord-006870-f5w6fw6q 4844 8 in in IN cord-006870-f5w6fw6q 4844 9 aSAH asah NN cord-006870-f5w6fw6q 4844 10 . . . cord-006870-f5w6fw6q 4845 1 In in IN cord-006870-f5w6fw6q 4845 2 our -PRON- PRP$ cord-006870-f5w6fw6q 4845 3 series series NN cord-006870-f5w6fw6q 4845 4 , , , cord-006870-f5w6fw6q 4845 5 OCT OCT NNP cord-006870-f5w6fw6q 4845 6 was be VBD cord-006870-f5w6fw6q 4845 7 a a DT cord-006870-f5w6fw6q 4845 8 safe safe JJ cord-006870-f5w6fw6q 4845 9 procedure procedure NN cord-006870-f5w6fw6q 4845 10 that that WDT cord-006870-f5w6fw6q 4845 11 enhanced enhance VBD cord-006870-f5w6fw6q 4845 12 TS ts NN cord-006870-f5w6fw6q 4845 13 detection detection NN cord-006870-f5w6fw6q 4845 14 by by IN cord-006870-f5w6fw6q 4845 15 decreasing decrease VBG cord-006870-f5w6fw6q 4845 16 false false JJ cord-006870-f5w6fw6q 4845 17 negative/ negative/ CD cord-006870-f5w6fw6q 4845 18 inconclusive inconclusive JJ cord-006870-f5w6fw6q 4845 19 fundoscopic fundoscopic NNP cord-006870-f5w6fw6q 4845 20 examinations examination NNS cord-006870-f5w6fw6q 4845 21 . . . cord-006870-f5w6fw6q 4846 1 It -PRON- PRP cord-006870-f5w6fw6q 4846 2 allows allow VBZ cord-006870-f5w6fw6q 4846 3 early early JJ cord-006870-f5w6fw6q 4846 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 4846 5 of of IN cord-006870-f5w6fw6q 4846 6 macular macular JJ cord-006870-f5w6fw6q 4846 7 holes hole NNS cord-006870-f5w6fw6q 4846 8 and and CC cord-006870-f5w6fw6q 4846 9 severe severe JJ cord-006870-f5w6fw6q 4846 10 retinal retinal JJ cord-006870-f5w6fw6q 4846 11 detachments detachment NNS cord-006870-f5w6fw6q 4846 12 , , , cord-006870-f5w6fw6q 4846 13 which which WDT cord-006870-f5w6fw6q 4846 14 require require VBP cord-006870-f5w6fw6q 4846 15 acute acute JJ cord-006870-f5w6fw6q 4846 16 surgical surgical JJ cord-006870-f5w6fw6q 4846 17 therapy therapy NN cord-006870-f5w6fw6q 4846 18 to to TO cord-006870-f5w6fw6q 4846 19 prevent prevent VB cord-006870-f5w6fw6q 4846 20 legal legal JJ cord-006870-f5w6fw6q 4846 21 blindness blindness NN cord-006870-f5w6fw6q 4846 22 . . . cord-006870-f5w6fw6q 4847 1 Besides besides RB cord-006870-f5w6fw6q 4847 2 , , , cord-006870-f5w6fw6q 4847 3 OCT OCT NNP cord-006870-f5w6fw6q 4847 4 aids aids NNP cord-006870-f5w6fw6q 4847 5 ruling rule VBG cord-006870-f5w6fw6q 4847 6 out out RP cord-006870-f5w6fw6q 4847 7 potential potential JJ cord-006870-f5w6fw6q 4847 8 false false JJ cord-006870-f5w6fw6q 4847 9 positive positive JJ cord-006870-f5w6fw6q 4847 10 visual visual JJ cord-006870-f5w6fw6q 4847 11 deficits deficit NNS cord-006870-f5w6fw6q 4847 12 in in IN cord-006870-f5w6fw6q 4847 13 individuals individual NNS cord-006870-f5w6fw6q 4847 14 with with IN cord-006870-f5w6fw6q 4847 15 a a DT cord-006870-f5w6fw6q 4847 16 depressed depressed JJ cord-006870-f5w6fw6q 4847 17 mood mood NN cord-006870-f5w6fw6q 4847 18 at at IN cord-006870-f5w6fw6q 4847 19 follow follow VB cord-006870-f5w6fw6q 4847 20 up up RP cord-006870-f5w6fw6q 4847 21 . . . cord-006870-f5w6fw6q 4848 1 A a DT cord-006870-f5w6fw6q 4848 2 comprehensive comprehensive JJ cord-006870-f5w6fw6q 4848 3 study study NN cord-006870-f5w6fw6q 4848 4 is be VBZ cord-006870-f5w6fw6q 4848 5 underway underway JJ cord-006870-f5w6fw6q 4848 6 to to TO cord-006870-f5w6fw6q 4848 7 understand understand VB cord-006870-f5w6fw6q 4848 8 the the DT cord-006870-f5w6fw6q 4848 9 impact impact NN cord-006870-f5w6fw6q 4848 10 OCT OCT NNP cord-006870-f5w6fw6q 4848 11 might may MD cord-006870-f5w6fw6q 4848 12 exert exert VB cord-006870-f5w6fw6q 4848 13 on on IN cord-006870-f5w6fw6q 4848 14 blindness blindness NN cord-006870-f5w6fw6q 4848 15 prevention prevention NN cord-006870-f5w6fw6q 4848 16 and and CC cord-006870-f5w6fw6q 4848 17 quality quality NN cord-006870-f5w6fw6q 4848 18 of of IN cord-006870-f5w6fw6q 4848 19 life life NN cord-006870-f5w6fw6q 4848 20 . . . cord-006870-f5w6fw6q 4849 1 Fever fever NN cord-006870-f5w6fw6q 4849 2 is be VBZ cord-006870-f5w6fw6q 4849 3 common common JJ cord-006870-f5w6fw6q 4849 4 in in IN cord-006870-f5w6fw6q 4849 5 patients patient NNS cord-006870-f5w6fw6q 4849 6 with with IN cord-006870-f5w6fw6q 4849 7 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4849 8 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4849 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4849 10 ( ( -LRB- cord-006870-f5w6fw6q 4849 11 aSAH aSAH NNP cord-006870-f5w6fw6q 4849 12 ) ) -RRB- cord-006870-f5w6fw6q 4849 13 , , , cord-006870-f5w6fw6q 4849 14 and and CC cord-006870-f5w6fw6q 4849 15 blood blood NN cord-006870-f5w6fw6q 4849 16 cultures culture NNS cord-006870-f5w6fw6q 4849 17 are be VBP cord-006870-f5w6fw6q 4849 18 commonly commonly RB cord-006870-f5w6fw6q 4849 19 sent send VBN cord-006870-f5w6fw6q 4849 20 to to TO cord-006870-f5w6fw6q 4849 21 diagnose diagnose VB cord-006870-f5w6fw6q 4849 22 etiology etiology NN cord-006870-f5w6fw6q 4849 23 . . . cord-006870-f5w6fw6q 4850 1 Several several JJ cord-006870-f5w6fw6q 4850 2 studies study NNS cord-006870-f5w6fw6q 4850 3 have have VBP cord-006870-f5w6fw6q 4850 4 shown show VBN cord-006870-f5w6fw6q 4850 5 a a DT cord-006870-f5w6fw6q 4850 6 low low JJ cord-006870-f5w6fw6q 4850 7 incidence incidence NN cord-006870-f5w6fw6q 4850 8 of of IN cord-006870-f5w6fw6q 4850 9 positive positive JJ cord-006870-f5w6fw6q 4850 10 blood blood NN cord-006870-f5w6fw6q 4850 11 cultures culture NNS cord-006870-f5w6fw6q 4850 12 , , , cord-006870-f5w6fw6q 4850 13 but but CC cord-006870-f5w6fw6q 4850 14 no no DT cord-006870-f5w6fw6q 4850 15 studies study NNS cord-006870-f5w6fw6q 4850 16 have have VBP cord-006870-f5w6fw6q 4850 17 assessed assess VBN cord-006870-f5w6fw6q 4850 18 blood blood NN cord-006870-f5w6fw6q 4850 19 cultures culture NNS cord-006870-f5w6fw6q 4850 20 in in IN cord-006870-f5w6fw6q 4850 21 patients patient NNS cord-006870-f5w6fw6q 4850 22 with with IN cord-006870-f5w6fw6q 4850 23 aSAH asah JJ cord-006870-f5w6fw6q 4850 24 . . . cord-006870-f5w6fw6q 4851 1 We -PRON- PRP cord-006870-f5w6fw6q 4851 2 performed perform VBD cord-006870-f5w6fw6q 4851 3 a a DT cord-006870-f5w6fw6q 4851 4 retrospective retrospective JJ cord-006870-f5w6fw6q 4851 5 analysis analysis NN cord-006870-f5w6fw6q 4851 6 of of IN cord-006870-f5w6fw6q 4851 7 patients patient NNS cord-006870-f5w6fw6q 4851 8 admitted admit VBN cord-006870-f5w6fw6q 4851 9 with with IN cord-006870-f5w6fw6q 4851 10 aSAH asah NN cord-006870-f5w6fw6q 4851 11 between between IN cord-006870-f5w6fw6q 4851 12 January January NNP cord-006870-f5w6fw6q 4851 13 2013 2013 CD cord-006870-f5w6fw6q 4851 14 to to IN cord-006870-f5w6fw6q 4851 15 December December NNP cord-006870-f5w6fw6q 4851 16 2015 2015 CD cord-006870-f5w6fw6q 4851 17 . . . cord-006870-f5w6fw6q 4852 1 Blood blood NN cord-006870-f5w6fw6q 4852 2 cultures culture NNS cord-006870-f5w6fw6q 4852 3 were be VBD cord-006870-f5w6fw6q 4852 4 adjudicated adjudicate VBN cord-006870-f5w6fw6q 4852 5 as as IN cord-006870-f5w6fw6q 4852 6 true true JJ cord-006870-f5w6fw6q 4852 7 positive positive JJ cord-006870-f5w6fw6q 4852 8 ( ( -LRB- cord-006870-f5w6fw6q 4852 9 TP tp NN cord-006870-f5w6fw6q 4852 10 ) ) -RRB- cord-006870-f5w6fw6q 4852 11 or or CC cord-006870-f5w6fw6q 4852 12 false false JJ cord-006870-f5w6fw6q 4852 13 positive positive JJ cord-006870-f5w6fw6q 4852 14 ( ( -LRB- cord-006870-f5w6fw6q 4852 15 FP FP NNP cord-006870-f5w6fw6q 4852 16 ) ) -RRB- cord-006870-f5w6fw6q 4852 17 based base VBN cord-006870-f5w6fw6q 4852 18 on on IN cord-006870-f5w6fw6q 4852 19 speciation speciation NN cord-006870-f5w6fw6q 4852 20 , , , cord-006870-f5w6fw6q 4852 21 time time NN cord-006870-f5w6fw6q 4852 22 to to IN cord-006870-f5w6fw6q 4852 23 positivity positivity NN cord-006870-f5w6fw6q 4852 24 , , , cord-006870-f5w6fw6q 4852 25 number number NN cord-006870-f5w6fw6q 4852 26 of of IN cord-006870-f5w6fw6q 4852 27 cultures culture NNS cord-006870-f5w6fw6q 4852 28 positive positive JJ cord-006870-f5w6fw6q 4852 29 , , , cord-006870-f5w6fw6q 4852 30 and and CC cord-006870-f5w6fw6q 4852 31 repeat repeat VB cord-006870-f5w6fw6q 4852 32 culture culture NN cord-006870-f5w6fw6q 4852 33 results result NNS cord-006870-f5w6fw6q 4852 34 . . . cord-006870-f5w6fw6q 4853 1 TP TP NNP cord-006870-f5w6fw6q 4853 2 patients patient NNS cord-006870-f5w6fw6q 4853 3 were be VBD cord-006870-f5w6fw6q 4853 4 compared compare VBN cord-006870-f5w6fw6q 4853 5 to to IN cord-006870-f5w6fw6q 4853 6 all all DT cord-006870-f5w6fw6q 4853 7 other other JJ cord-006870-f5w6fw6q 4853 8 patients patient NNS cord-006870-f5w6fw6q 4853 9 . . . cord-006870-f5w6fw6q 4854 1 Age age NN cord-006870-f5w6fw6q 4854 2 , , , cord-006870-f5w6fw6q 4854 3 gender gender NN cord-006870-f5w6fw6q 4854 4 , , , cord-006870-f5w6fw6q 4854 5 Hunt Hunt NNP cord-006870-f5w6fw6q 4854 6 Hess Hess NNP cord-006870-f5w6fw6q 4854 7 , , , cord-006870-f5w6fw6q 4854 8 Modified Modified NNP cord-006870-f5w6fw6q 4854 9 Fisher Fisher NNP cord-006870-f5w6fw6q 4854 10 , , , cord-006870-f5w6fw6q 4854 11 aneurysm aneurysm NN cord-006870-f5w6fw6q 4854 12 treatment treatment NN cord-006870-f5w6fw6q 4854 13 , , , cord-006870-f5w6fw6q 4854 14 incidence incidence NN cord-006870-f5w6fw6q 4854 15 of of IN cord-006870-f5w6fw6q 4854 16 delayed delay VBN cord-006870-f5w6fw6q 4854 17 cerebral cerebral JJ cord-006870-f5w6fw6q 4854 18 ischemia ischemia NN cord-006870-f5w6fw6q 4854 19 ( ( -LRB- cord-006870-f5w6fw6q 4854 20 DCI DCI NNP cord-006870-f5w6fw6q 4854 21 ) ) -RRB- cord-006870-f5w6fw6q 4854 22 , , , cord-006870-f5w6fw6q 4854 23 length length NN cord-006870-f5w6fw6q 4854 24 of of IN cord-006870-f5w6fw6q 4854 25 stay stay NN cord-006870-f5w6fw6q 4854 26 ( ( -LRB- cord-006870-f5w6fw6q 4854 27 LOS LOS NNP cord-006870-f5w6fw6q 4854 28 ) ) -RRB- cord-006870-f5w6fw6q 4854 29 , , , cord-006870-f5w6fw6q 4854 30 and and CC cord-006870-f5w6fw6q 4854 31 neurological neurological JJ cord-006870-f5w6fw6q 4854 32 outcomes outcome NNS cord-006870-f5w6fw6q 4854 33 were be VBD cord-006870-f5w6fw6q 4854 34 analyzed analyze VBN cord-006870-f5w6fw6q 4854 35 . . . cord-006870-f5w6fw6q 4855 1 324 324 CD cord-006870-f5w6fw6q 4855 2 patients patient NNS cord-006870-f5w6fw6q 4855 3 with with IN cord-006870-f5w6fw6q 4855 4 aSAH asah JJ cord-006870-f5w6fw6q 4855 5 were be VBD cord-006870-f5w6fw6q 4855 6 included include VBN cord-006870-f5w6fw6q 4855 7 . . . cord-006870-f5w6fw6q 4856 1 Blood blood NN cord-006870-f5w6fw6q 4856 2 cultures culture NNS cord-006870-f5w6fw6q 4856 3 were be VBD cord-006870-f5w6fw6q 4856 4 sent send VBN cord-006870-f5w6fw6q 4856 5 on on IN cord-006870-f5w6fw6q 4856 6 195 195 CD cord-006870-f5w6fw6q 4856 7 ( ( -LRB- cord-006870-f5w6fw6q 4856 8 60 60 CD cord-006870-f5w6fw6q 4856 9 % % NN cord-006870-f5w6fw6q 4856 10 ) ) -RRB- cord-006870-f5w6fw6q 4856 11 . . . cord-006870-f5w6fw6q 4857 1 Sixteen sixteen CD cord-006870-f5w6fw6q 4857 2 were be VBD cord-006870-f5w6fw6q 4857 3 positive positive JJ cord-006870-f5w6fw6q 4857 4 . . . cord-006870-f5w6fw6q 4858 1 Eleven eleven CD cord-006870-f5w6fw6q 4858 2 were be VBD cord-006870-f5w6fw6q 4858 3 adjudicated adjudicate VBN cord-006870-f5w6fw6q 4858 4 TP tp NN cord-006870-f5w6fw6q 4858 5 and and CC cord-006870-f5w6fw6q 4858 6 5 5 CD cord-006870-f5w6fw6q 4858 7 FP FP NNP cord-006870-f5w6fw6q 4858 8 . . . cord-006870-f5w6fw6q 4859 1 Thus thus RB cord-006870-f5w6fw6q 4859 2 , , , cord-006870-f5w6fw6q 4859 3 3.4 3.4 CD cord-006870-f5w6fw6q 4859 4 % % NN cord-006870-f5w6fw6q 4859 5 ( ( -LRB- cord-006870-f5w6fw6q 4859 6 11/324 11/324 CD cord-006870-f5w6fw6q 4859 7 ) ) -RRB- cord-006870-f5w6fw6q 4859 8 of of IN cord-006870-f5w6fw6q 4859 9 patients patient NNS cord-006870-f5w6fw6q 4859 10 had have VBD cord-006870-f5w6fw6q 4859 11 true true JJ cord-006870-f5w6fw6q 4859 12 bacteremia bacteremia NN cord-006870-f5w6fw6q 4859 13 , , , cord-006870-f5w6fw6q 4859 14 and and CC cord-006870-f5w6fw6q 4859 15 blood blood NN cord-006870-f5w6fw6q 4859 16 culture culture NN cord-006870-f5w6fw6q 4859 17 yield yield NN cord-006870-f5w6fw6q 4859 18 for for IN cord-006870-f5w6fw6q 4859 19 true true JJ cord-006870-f5w6fw6q 4859 20 infection infection NN cord-006870-f5w6fw6q 4859 21 was be VBD cord-006870-f5w6fw6q 4859 22 5.6 5.6 CD cord-006870-f5w6fw6q 4859 23 % % NN cord-006870-f5w6fw6q 4859 24 ( ( -LRB- cord-006870-f5w6fw6q 4859 25 11/195 11/195 CD cord-006870-f5w6fw6q 4859 26 ) ) -RRB- cord-006870-f5w6fw6q 4859 27 . . . cord-006870-f5w6fw6q 4860 1 FP FP NNP cord-006870-f5w6fw6q 4860 2 rate rate NN cord-006870-f5w6fw6q 4860 3 was be VBD cord-006870-f5w6fw6q 4860 4 2.6 2.6 CD cord-006870-f5w6fw6q 4860 5 % % NN cord-006870-f5w6fw6q 4860 6 ( ( -LRB- cord-006870-f5w6fw6q 4860 7 5/195 5/195 CD cord-006870-f5w6fw6q 4860 8 ) ) -RRB- cord-006870-f5w6fw6q 4860 9 . . . cord-006870-f5w6fw6q 4861 1 Eight eight CD cord-006870-f5w6fw6q 4861 2 TPs tp NNS cord-006870-f5w6fw6q 4861 3 were be VBD cord-006870-f5w6fw6q 4861 4 gram gram NN cord-006870-f5w6fw6q 4861 5 negative negative JJ cord-006870-f5w6fw6q 4861 6 ( ( -LRB- cord-006870-f5w6fw6q 4861 7 73 73 CD cord-006870-f5w6fw6q 4861 8 % % NN cord-006870-f5w6fw6q 4861 9 ) ) -RRB- cord-006870-f5w6fw6q 4861 10 , , , cord-006870-f5w6fw6q 4861 11 and and CC cord-006870-f5w6fw6q 4861 12 all all DT cord-006870-f5w6fw6q 4861 13 contaminants contaminant NNS cord-006870-f5w6fw6q 4861 14 were be VBD cord-006870-f5w6fw6q 4861 15 Staphylococcus Staphylococcus NNP cord-006870-f5w6fw6q 4861 16 non non JJ cord-006870-f5w6fw6q 4861 17 - - JJ cord-006870-f5w6fw6q 4861 18 aureus aureus JJ cord-006870-f5w6fw6q 4861 19 . . . cord-006870-f5w6fw6q 4862 1 Median median JJ cord-006870-f5w6fw6q 4862 2 post post JJ cord-006870-f5w6fw6q 4862 3 - - JJ cord-006870-f5w6fw6q 4862 4 bleed bleed JJ cord-006870-f5w6fw6q 4862 5 day day NN cord-006870-f5w6fw6q 4862 6 for for IN cord-006870-f5w6fw6q 4862 7 TP tp NN cord-006870-f5w6fw6q 4862 8 results result NNS cord-006870-f5w6fw6q 4862 9 was be VBD cord-006870-f5w6fw6q 4862 10 23 23 CD cord-006870-f5w6fw6q 4862 11 . . . cord-006870-f5w6fw6q 4863 1 Only only RB cord-006870-f5w6fw6q 4863 2 3 3 CD cord-006870-f5w6fw6q 4863 3 patients patient NNS cord-006870-f5w6fw6q 4863 4 were be VBD cord-006870-f5w6fw6q 4863 5 TP tp NN cord-006870-f5w6fw6q 4863 6 within within IN cord-006870-f5w6fw6q 4863 7 the the DT cord-006870-f5w6fw6q 4863 8 first first JJ cord-006870-f5w6fw6q 4863 9 week week NN cord-006870-f5w6fw6q 4863 10 of of IN cord-006870-f5w6fw6q 4863 11 admission admission NN cord-006870-f5w6fw6q 4863 12 ( ( -LRB- cord-006870-f5w6fw6q 4863 13 0.9 0.9 CD cord-006870-f5w6fw6q 4863 14 % % NN cord-006870-f5w6fw6q 4863 15 ) ) -RRB- cord-006870-f5w6fw6q 4863 16 . . . cord-006870-f5w6fw6q 4864 1 TP TP NNP cord-006870-f5w6fw6q 4864 2 patients patient NNS cord-006870-f5w6fw6q 4864 3 had have VBD cord-006870-f5w6fw6q 4864 4 higher high JJR cord-006870-f5w6fw6q 4864 5 admission admission NN cord-006870-f5w6fw6q 4864 6 WFNS WFNS NNP cord-006870-f5w6fw6q 4864 7 ( ( -LRB- cord-006870-f5w6fw6q 4864 8 p=.015 p=.015 JJ cord-006870-f5w6fw6q 4864 9 ) ) -RRB- cord-006870-f5w6fw6q 4864 10 and and CC cord-006870-f5w6fw6q 4864 11 IVH IVH NNP cord-006870-f5w6fw6q 4864 12 score score NN cord-006870-f5w6fw6q 4864 13 ( ( -LRB- cord-006870-f5w6fw6q 4864 14 p=.006 p=.006 NNP cord-006870-f5w6fw6q 4864 15 ) ) -RRB- cord-006870-f5w6fw6q 4864 16 , , , cord-006870-f5w6fw6q 4864 17 but but CC cord-006870-f5w6fw6q 4864 18 age age NN cord-006870-f5w6fw6q 4864 19 , , , cord-006870-f5w6fw6q 4864 20 gender gender NN cord-006870-f5w6fw6q 4864 21 , , , cord-006870-f5w6fw6q 4864 22 aneurysm aneurysm NN cord-006870-f5w6fw6q 4864 23 treatment treatment NN cord-006870-f5w6fw6q 4864 24 , , , cord-006870-f5w6fw6q 4864 25 and and CC cord-006870-f5w6fw6q 4864 26 Fisher Fisher NNP cord-006870-f5w6fw6q 4864 27 score score NN cord-006870-f5w6fw6q 4864 28 did do VBD cord-006870-f5w6fw6q 4864 29 not not RB cord-006870-f5w6fw6q 4864 30 differ differ VB cord-006870-f5w6fw6q 4864 31 . . . cord-006870-f5w6fw6q 4865 1 TP TP NNP cord-006870-f5w6fw6q 4865 2 patients patient NNS cord-006870-f5w6fw6q 4865 3 had have VBD cord-006870-f5w6fw6q 4865 4 longer long JJR cord-006870-f5w6fw6q 4865 5 ICU ICU NNP cord-006870-f5w6fw6q 4865 6 and and CC cord-006870-f5w6fw6q 4865 7 hospital hospital NN cord-006870-f5w6fw6q 4865 8 LOS LOS NNP cord-006870-f5w6fw6q 4865 9 and and CC cord-006870-f5w6fw6q 4865 10 higher high JJR cord-006870-f5w6fw6q 4865 11 incidence incidence NN cord-006870-f5w6fw6q 4865 12 of of IN cord-006870-f5w6fw6q 4865 13 DCI DCI NNP cord-006870-f5w6fw6q 4865 14 ( ( -LRB- cord-006870-f5w6fw6q 4865 15 56 56 CD cord-006870-f5w6fw6q 4865 16 % % NN cord-006870-f5w6fw6q 4865 17 vs vs IN cord-006870-f5w6fw6q 4865 18 27 27 CD cord-006870-f5w6fw6q 4865 19 % % NN cord-006870-f5w6fw6q 4865 20 , , , cord-006870-f5w6fw6q 4865 21 p=.026 p=.026 NN cord-006870-f5w6fw6q 4865 22 ) ) -RRB- cord-006870-f5w6fw6q 4865 23 . . . cord-006870-f5w6fw6q 4866 1 Mortality mortality NN cord-006870-f5w6fw6q 4866 2 did do VBD cord-006870-f5w6fw6q 4866 3 not not RB cord-006870-f5w6fw6q 4866 4 differ differ VB cord-006870-f5w6fw6q 4866 5 in in IN cord-006870-f5w6fw6q 4866 6 the the DT cord-006870-f5w6fw6q 4866 7 two two CD cord-006870-f5w6fw6q 4866 8 groups group NNS cord-006870-f5w6fw6q 4866 9 either either RB cord-006870-f5w6fw6q 4866 10 . . . cord-006870-f5w6fw6q 4867 1 The the DT cord-006870-f5w6fw6q 4867 2 yield yield NN cord-006870-f5w6fw6q 4867 3 of of IN cord-006870-f5w6fw6q 4867 4 blood blood NN cord-006870-f5w6fw6q 4867 5 cultures culture NNS cord-006870-f5w6fw6q 4867 6 in in IN cord-006870-f5w6fw6q 4867 7 aSAH asah JJ cord-006870-f5w6fw6q 4867 8 patients patient NNS cord-006870-f5w6fw6q 4867 9 is be VBZ cord-006870-f5w6fw6q 4867 10 low low JJ cord-006870-f5w6fw6q 4867 11 . . . cord-006870-f5w6fw6q 4868 1 Even even RB cord-006870-f5w6fw6q 4868 2 with with IN cord-006870-f5w6fw6q 4868 3 a a DT cord-006870-f5w6fw6q 4868 4 contamination contamination NN cord-006870-f5w6fw6q 4868 5 rate rate NN cord-006870-f5w6fw6q 4868 6 under under IN cord-006870-f5w6fw6q 4868 7 3 3 CD cord-006870-f5w6fw6q 4868 8 % % NN cord-006870-f5w6fw6q 4868 9 , , , cord-006870-f5w6fw6q 4868 10 31 31 CD cord-006870-f5w6fw6q 4868 11 % % NN cord-006870-f5w6fw6q 4868 12 of of IN cord-006870-f5w6fw6q 4868 13 positive positive JJ cord-006870-f5w6fw6q 4868 14 blood blood NN cord-006870-f5w6fw6q 4868 15 cultures culture NNS cord-006870-f5w6fw6q 4868 16 are be VBP cord-006870-f5w6fw6q 4868 17 FP FP NNP cord-006870-f5w6fw6q 4868 18 . . . cord-006870-f5w6fw6q 4869 1 Future future JJ cord-006870-f5w6fw6q 4869 2 studies study NNS cord-006870-f5w6fw6q 4869 3 should should MD cord-006870-f5w6fw6q 4869 4 evaluate evaluate VB cord-006870-f5w6fw6q 4869 5 factors factor NNS cord-006870-f5w6fw6q 4869 6 to to TO cord-006870-f5w6fw6q 4869 7 identify identify VB cord-006870-f5w6fw6q 4869 8 patients patient NNS cord-006870-f5w6fw6q 4869 9 at at IN cord-006870-f5w6fw6q 4869 10 higher high JJR cord-006870-f5w6fw6q 4869 11 risk risk NN cord-006870-f5w6fw6q 4869 12 of of IN cord-006870-f5w6fw6q 4869 13 bacteremia bacteremia NN cord-006870-f5w6fw6q 4869 14 to to TO cord-006870-f5w6fw6q 4869 15 reduce reduce VB cord-006870-f5w6fw6q 4869 16 costs cost NNS cord-006870-f5w6fw6q 4869 17 and and CC cord-006870-f5w6fw6q 4869 18 improve improve VB cord-006870-f5w6fw6q 4869 19 care care NN cord-006870-f5w6fw6q 4869 20 . . . cord-006870-f5w6fw6q 4870 1 Intra intra JJ cord-006870-f5w6fw6q 4870 2 - - JJ cord-006870-f5w6fw6q 4870 3 arterial arterial JJ cord-006870-f5w6fw6q 4870 4 verapamil verapamil NN cord-006870-f5w6fw6q 4870 5 therapy therapy NN cord-006870-f5w6fw6q 4870 6 reduces reduce VBZ cord-006870-f5w6fw6q 4870 7 cerebral cerebral JJ cord-006870-f5w6fw6q 4870 8 vasospasm vasospasm NN cord-006870-f5w6fw6q 4870 9 after after IN cord-006870-f5w6fw6q 4870 10 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4870 11 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4870 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4870 13 ( ( -LRB- cord-006870-f5w6fw6q 4870 14 SAH SAH NNP cord-006870-f5w6fw6q 4870 15 ) ) -RRB- cord-006870-f5w6fw6q 4870 16 . . . cord-006870-f5w6fw6q 4871 1 There there EX cord-006870-f5w6fw6q 4871 2 is be VBZ cord-006870-f5w6fw6q 4871 3 little little JJ cord-006870-f5w6fw6q 4871 4 literature literature NN cord-006870-f5w6fw6q 4871 5 that that WDT cord-006870-f5w6fw6q 4871 6 quantitatively quantitatively RB cord-006870-f5w6fw6q 4871 7 describes describe VBZ cord-006870-f5w6fw6q 4871 8 its -PRON- PRP$ cord-006870-f5w6fw6q 4871 9 safety safety NN cord-006870-f5w6fw6q 4871 10 , , , cord-006870-f5w6fw6q 4871 11 required require VBN cord-006870-f5w6fw6q 4871 12 dosing dosing NN cord-006870-f5w6fw6q 4871 13 , , , cord-006870-f5w6fw6q 4871 14 or or CC cord-006870-f5w6fw6q 4871 15 efficacy efficacy NN cord-006870-f5w6fw6q 4871 16 . . . cord-006870-f5w6fw6q 4872 1 As as IN cord-006870-f5w6fw6q 4872 2 a a DT cord-006870-f5w6fw6q 4872 3 result result NN cord-006870-f5w6fw6q 4872 4 , , , cord-006870-f5w6fw6q 4872 5 therapeutic therapeutic JJ cord-006870-f5w6fw6q 4872 6 outcomes outcome NNS cord-006870-f5w6fw6q 4872 7 need need VBP cord-006870-f5w6fw6q 4872 8 to to TO cord-006870-f5w6fw6q 4872 9 be be VB cord-006870-f5w6fw6q 4872 10 subjectively subjectively RB cord-006870-f5w6fw6q 4872 11 analyzed analyze VBN cord-006870-f5w6fw6q 4872 12 by by IN cord-006870-f5w6fw6q 4872 13 experienced experienced JJ cord-006870-f5w6fw6q 4872 14 radiologists radiologist NNS cord-006870-f5w6fw6q 4872 15 during during IN cord-006870-f5w6fw6q 4872 16 the the DT cord-006870-f5w6fw6q 4872 17 intervention intervention NN cord-006870-f5w6fw6q 4872 18 and and CC cord-006870-f5w6fw6q 4872 19 clinically clinically RB cord-006870-f5w6fw6q 4872 20 correlated correlate VBN cord-006870-f5w6fw6q 4872 21 by by IN cord-006870-f5w6fw6q 4872 22 cerebral cerebral JJ cord-006870-f5w6fw6q 4872 23 perfusion perfusion NN cord-006870-f5w6fw6q 4872 24 pressure pressure NN cord-006870-f5w6fw6q 4872 25 , , , cord-006870-f5w6fw6q 4872 26 intracranial intracranial JJ cord-006870-f5w6fw6q 4872 27 pressures pressure NNS cord-006870-f5w6fw6q 4872 28 and and CC cord-006870-f5w6fw6q 4872 29 Transcranial transcranial JJ cord-006870-f5w6fw6q 4872 30 Dopplers doppler NNS cord-006870-f5w6fw6q 4872 31 . . . cord-006870-f5w6fw6q 4873 1 We -PRON- PRP cord-006870-f5w6fw6q 4873 2 present present VBP cord-006870-f5w6fw6q 4873 3 a a DT cord-006870-f5w6fw6q 4873 4 novel novel NN cord-006870-f5w6fw6q 4873 5 imaging imaging NN cord-006870-f5w6fw6q 4873 6 analysis analysis NN cord-006870-f5w6fw6q 4873 7 to to TO cord-006870-f5w6fw6q 4873 8 quantify quantify VB cord-006870-f5w6fw6q 4873 9 cerebral cerebral JJ cord-006870-f5w6fw6q 4873 10 perfusion perfusion NN cord-006870-f5w6fw6q 4873 11 in in IN cord-006870-f5w6fw6q 4873 12 realtime realtime NN cord-006870-f5w6fw6q 4873 13 and and CC cord-006870-f5w6fw6q 4873 14 apply apply VB cord-006870-f5w6fw6q 4873 15 this this DT cord-006870-f5w6fw6q 4873 16 technology technology NN cord-006870-f5w6fw6q 4873 17 to to IN cord-006870-f5w6fw6q 4873 18 patients patient NNS cord-006870-f5w6fw6q 4873 19 undergoing undergo VBG cord-006870-f5w6fw6q 4873 20 therapy therapy NN cord-006870-f5w6fw6q 4873 21 for for IN cord-006870-f5w6fw6q 4873 22 vasospasm vasospasm NN cord-006870-f5w6fw6q 4873 23 . . . cord-006870-f5w6fw6q 4874 1 We -PRON- PRP cord-006870-f5w6fw6q 4874 2 developed develop VBD cord-006870-f5w6fw6q 4874 3 software software NN cord-006870-f5w6fw6q 4874 4 to to TO cord-006870-f5w6fw6q 4874 5 evaluate evaluate VB cord-006870-f5w6fw6q 4874 6 changes change NNS cord-006870-f5w6fw6q 4874 7 in in IN cord-006870-f5w6fw6q 4874 8 contrast contrast JJ cord-006870-f5w6fw6q 4874 9 flow flow NN cord-006870-f5w6fw6q 4874 10 dynamics dynamic NNS cord-006870-f5w6fw6q 4874 11 for for IN cord-006870-f5w6fw6q 4874 12 digital digital JJ cord-006870-f5w6fw6q 4874 13 subtraction subtraction NN cord-006870-f5w6fw6q 4874 14 angiography angiography NN cord-006870-f5w6fw6q 4874 15 ( ( -LRB- cord-006870-f5w6fw6q 4874 16 DSA DSA NNP cord-006870-f5w6fw6q 4874 17 ) ) -RRB- cord-006870-f5w6fw6q 4874 18 scans scan NNS cord-006870-f5w6fw6q 4874 19 performed perform VBN cord-006870-f5w6fw6q 4874 20 pre pre JJ cord-006870-f5w6fw6q 4874 21 - - JJ cord-006870-f5w6fw6q 4874 22 and and CC cord-006870-f5w6fw6q 4874 23 post post JJ cord-006870-f5w6fw6q 4874 24 - - JJ cord-006870-f5w6fw6q 4874 25 intra intra JJ cord-006870-f5w6fw6q 4874 26 - - JJ cord-006870-f5w6fw6q 4874 27 arterial arterial JJ cord-006870-f5w6fw6q 4874 28 therapy therapy NN cord-006870-f5w6fw6q 4874 29 for for IN cord-006870-f5w6fw6q 4874 30 vasospasm vasospasm NN cord-006870-f5w6fw6q 4874 31 . . . cord-006870-f5w6fw6q 4875 1 Performing perform VBG cord-006870-f5w6fw6q 4875 2 signal signal NN cord-006870-f5w6fw6q 4875 3 intensity intensity NN cord-006870-f5w6fw6q 4875 4 curve curve NN cord-006870-f5w6fw6q 4875 5 deconvolution deconvolution NN cord-006870-f5w6fw6q 4875 6 on on IN cord-006870-f5w6fw6q 4875 7 a a DT cord-006870-f5w6fw6q 4875 8 voxel voxel NN cord-006870-f5w6fw6q 4875 9 by by IN cord-006870-f5w6fw6q 4875 10 voxel voxel NNP cord-006870-f5w6fw6q 4875 11 basis basis NN cord-006870-f5w6fw6q 4875 12 provides provide VBZ cord-006870-f5w6fw6q 4875 13 quantitative quantitative JJ cord-006870-f5w6fw6q 4875 14 2D 2d NN cord-006870-f5w6fw6q 4875 15 perfusion perfusion NN cord-006870-f5w6fw6q 4875 16 parameters parameter NNS cord-006870-f5w6fw6q 4875 17 including include VBG cord-006870-f5w6fw6q 4875 18 : : : cord-006870-f5w6fw6q 4875 19 time time NN cord-006870-f5w6fw6q 4875 20 to to TO cord-006870-f5w6fw6q 4875 21 peak peak VB cord-006870-f5w6fw6q 4875 22 , , , cord-006870-f5w6fw6q 4875 23 time time NN cord-006870-f5w6fw6q 4875 24 to to TO cord-006870-f5w6fw6q 4875 25 drain drain VB cord-006870-f5w6fw6q 4875 26 , , , cord-006870-f5w6fw6q 4875 27 area area NN cord-006870-f5w6fw6q 4875 28 under under IN cord-006870-f5w6fw6q 4875 29 the the DT cord-006870-f5w6fw6q 4875 30 curve curve NN cord-006870-f5w6fw6q 4875 31 , , , cord-006870-f5w6fw6q 4875 32 root root NN cord-006870-f5w6fw6q 4875 33 mean mean VB cord-006870-f5w6fw6q 4875 34 transit transit NN cord-006870-f5w6fw6q 4875 35 time time NN cord-006870-f5w6fw6q 4875 36 , , , cord-006870-f5w6fw6q 4875 37 arrival arrival NN cord-006870-f5w6fw6q 4875 38 time time NN cord-006870-f5w6fw6q 4875 39 , , , cord-006870-f5w6fw6q 4875 40 tissue tissue NN cord-006870-f5w6fw6q 4875 41 concentration concentration NN cord-006870-f5w6fw6q 4875 42 , , , cord-006870-f5w6fw6q 4875 43 arterial arterial JJ cord-006870-f5w6fw6q 4875 44 input input NN cord-006870-f5w6fw6q 4875 45 functions function NNS cord-006870-f5w6fw6q 4875 46 and and CC cord-006870-f5w6fw6q 4875 47 cerebral cerebral JJ cord-006870-f5w6fw6q 4875 48 blood blood NN cord-006870-f5w6fw6q 4875 49 flow flow NN cord-006870-f5w6fw6q 4875 50 at at IN cord-006870-f5w6fw6q 4875 51 each each DT cord-006870-f5w6fw6q 4875 52 voxel voxel NN cord-006870-f5w6fw6q 4875 53 . . . cord-006870-f5w6fw6q 4876 1 After after IN cord-006870-f5w6fw6q 4876 2 aligning align VBG cord-006870-f5w6fw6q 4876 3 perfusion perfusion NN cord-006870-f5w6fw6q 4876 4 studies study NNS cord-006870-f5w6fw6q 4876 5 , , , cord-006870-f5w6fw6q 4876 6 our -PRON- PRP$ cord-006870-f5w6fw6q 4876 7 software software NN cord-006870-f5w6fw6q 4876 8 then then RB cord-006870-f5w6fw6q 4876 9 displays display VBZ cord-006870-f5w6fw6q 4876 10 and and CC cord-006870-f5w6fw6q 4876 11 automatically automatically RB cord-006870-f5w6fw6q 4876 12 creates create VBZ cord-006870-f5w6fw6q 4876 13 regions region NNS cord-006870-f5w6fw6q 4876 14 of of IN cord-006870-f5w6fw6q 4876 15 interests interest NNS cord-006870-f5w6fw6q 4876 16 for for IN cord-006870-f5w6fw6q 4876 17 changes change NNS cord-006870-f5w6fw6q 4876 18 in in IN cord-006870-f5w6fw6q 4876 19 perfusion perfusion NN cord-006870-f5w6fw6q 4876 20 to to TO cord-006870-f5w6fw6q 4876 21 visualize visualize VB cord-006870-f5w6fw6q 4876 22 the the DT cord-006870-f5w6fw6q 4876 23 effects effect NNS cord-006870-f5w6fw6q 4876 24 of of IN cord-006870-f5w6fw6q 4876 25 interventions intervention NNS cord-006870-f5w6fw6q 4876 26 . . . cord-006870-f5w6fw6q 4877 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4877 2 software software NN cord-006870-f5w6fw6q 4877 3 quantitatively quantitatively RB cord-006870-f5w6fw6q 4877 4 measures measure VBZ cord-006870-f5w6fw6q 4877 5 perfusion perfusion NN cord-006870-f5w6fw6q 4877 6 from from IN cord-006870-f5w6fw6q 4877 7 DSAs dsa NNS cord-006870-f5w6fw6q 4877 8 and and CC cord-006870-f5w6fw6q 4877 9 can can MD cord-006870-f5w6fw6q 4877 10 normalize normalize VB cord-006870-f5w6fw6q 4877 11 two two CD cord-006870-f5w6fw6q 4877 12 DSAs dsa NNS cord-006870-f5w6fw6q 4877 13 accounting account VBG cord-006870-f5w6fw6q 4877 14 for for IN cord-006870-f5w6fw6q 4877 15 differences difference NNS cord-006870-f5w6fw6q 4877 16 in in IN cord-006870-f5w6fw6q 4877 17 volume volume NN cord-006870-f5w6fw6q 4877 18 and and CC cord-006870-f5w6fw6q 4877 19 speed speed NN cord-006870-f5w6fw6q 4877 20 of of IN cord-006870-f5w6fw6q 4877 21 contrast contrast JJ cord-006870-f5w6fw6q 4877 22 administration administration NN cord-006870-f5w6fw6q 4877 23 . . . cord-006870-f5w6fw6q 4878 1 Two two CD cord-006870-f5w6fw6q 4878 2 applications application NNS cord-006870-f5w6fw6q 4878 3 of of IN cord-006870-f5w6fw6q 4878 4 this this DT cord-006870-f5w6fw6q 4878 5 technology technology NN cord-006870-f5w6fw6q 4878 6 are be VBP cord-006870-f5w6fw6q 4878 7 demonstrated demonstrate VBN cord-006870-f5w6fw6q 4878 8 . . . cord-006870-f5w6fw6q 4879 1 The the DT cord-006870-f5w6fw6q 4879 2 first first JJ cord-006870-f5w6fw6q 4879 3 subtracts subtract VBZ cord-006870-f5w6fw6q 4879 4 perfusion perfusion NN cord-006870-f5w6fw6q 4879 5 from from IN cord-006870-f5w6fw6q 4879 6 pre pre JJ cord-006870-f5w6fw6q 4879 7 - - JJ cord-006870-f5w6fw6q 4879 8 and and CC cord-006870-f5w6fw6q 4879 9 post post VB cord-006870-f5w6fw6q 4879 10 intra intra JJ cord-006870-f5w6fw6q 4879 11 - - JJ cord-006870-f5w6fw6q 4879 12 arterial arterial JJ cord-006870-f5w6fw6q 4879 13 interventions intervention NNS cord-006870-f5w6fw6q 4879 14 quantifying quantify VBG cord-006870-f5w6fw6q 4879 15 exact exact JJ cord-006870-f5w6fw6q 4879 16 changes change NNS cord-006870-f5w6fw6q 4879 17 in in IN cord-006870-f5w6fw6q 4879 18 perfusion perfusion NN cord-006870-f5w6fw6q 4879 19 at at IN cord-006870-f5w6fw6q 4879 20 each each DT cord-006870-f5w6fw6q 4879 21 voxel voxel NN cord-006870-f5w6fw6q 4879 22 . . . cord-006870-f5w6fw6q 4880 1 The the DT cord-006870-f5w6fw6q 4880 2 second second NN cord-006870-f5w6fw6q 4880 3 compares compare VBZ cord-006870-f5w6fw6q 4880 4 two two CD cord-006870-f5w6fw6q 4880 5 DSA DSA NNP cord-006870-f5w6fw6q 4880 6 studies study NNS cord-006870-f5w6fw6q 4880 7 of of IN cord-006870-f5w6fw6q 4880 8 the the DT cord-006870-f5w6fw6q 4880 9 same same JJ cord-006870-f5w6fw6q 4880 10 patient patient NN cord-006870-f5w6fw6q 4880 11 at at IN cord-006870-f5w6fw6q 4880 12 different different JJ cord-006870-f5w6fw6q 4880 13 dates date NNS cord-006870-f5w6fw6q 4880 14 to to TO cord-006870-f5w6fw6q 4880 15 contour contour VB cord-006870-f5w6fw6q 4880 16 the the DT cord-006870-f5w6fw6q 4880 17 territories territory NNS cord-006870-f5w6fw6q 4880 18 susceptible susceptible JJ cord-006870-f5w6fw6q 4880 19 to to IN cord-006870-f5w6fw6q 4880 20 delayed delay VBN cord-006870-f5w6fw6q 4880 21 cerebral cerebral JJ cord-006870-f5w6fw6q 4880 22 ischemia ischemia NN cord-006870-f5w6fw6q 4880 23 . . . cord-006870-f5w6fw6q 4881 1 We -PRON- PRP cord-006870-f5w6fw6q 4881 2 compare compare VBP cord-006870-f5w6fw6q 4881 3 this this DT cord-006870-f5w6fw6q 4881 4 analysis analysis NN cord-006870-f5w6fw6q 4881 5 to to IN cord-006870-f5w6fw6q 4881 6 MRI MRI NNP cord-006870-f5w6fw6q 4881 7 imaging imaging NN cord-006870-f5w6fw6q 4881 8 when when WRB cord-006870-f5w6fw6q 4881 9 applicable applicable JJ cord-006870-f5w6fw6q 4881 10 demonstrating demonstrate VBG cord-006870-f5w6fw6q 4881 11 ischemic ischemic JJ cord-006870-f5w6fw6q 4881 12 changes change NNS cord-006870-f5w6fw6q 4881 13 aligning align VBG cord-006870-f5w6fw6q 4881 14 to to IN cord-006870-f5w6fw6q 4881 15 the the DT cord-006870-f5w6fw6q 4881 16 susceptible susceptible JJ cord-006870-f5w6fw6q 4881 17 territories territory NNS cord-006870-f5w6fw6q 4881 18 outlined outline VBN cord-006870-f5w6fw6q 4881 19 by by IN cord-006870-f5w6fw6q 4881 20 our -PRON- PRP$ cord-006870-f5w6fw6q 4881 21 analysis analysis NN cord-006870-f5w6fw6q 4881 22 . . . cord-006870-f5w6fw6q 4882 1 DSA DSA NNP cord-006870-f5w6fw6q 4882 2 based base VBN cord-006870-f5w6fw6q 4882 3 perfusion perfusion NN cord-006870-f5w6fw6q 4882 4 is be VBZ cord-006870-f5w6fw6q 4882 5 an an DT cord-006870-f5w6fw6q 4882 6 effective effective JJ cord-006870-f5w6fw6q 4882 7 study study NN cord-006870-f5w6fw6q 4882 8 to to TO cord-006870-f5w6fw6q 4882 9 quantify quantify VB cord-006870-f5w6fw6q 4882 10 the the DT cord-006870-f5w6fw6q 4882 11 need need NN cord-006870-f5w6fw6q 4882 12 for for IN cord-006870-f5w6fw6q 4882 13 and and CC cord-006870-f5w6fw6q 4882 14 the the DT cord-006870-f5w6fw6q 4882 15 precise precise JJ cord-006870-f5w6fw6q 4882 16 effects effect NNS cord-006870-f5w6fw6q 4882 17 of of IN cord-006870-f5w6fw6q 4882 18 endovascular endovascular JJ cord-006870-f5w6fw6q 4882 19 interventions intervention NNS cord-006870-f5w6fw6q 4882 20 . . . cord-006870-f5w6fw6q 4883 1 Quantitative quantitative JJ cord-006870-f5w6fw6q 4883 2 thresholds threshold NNS cord-006870-f5w6fw6q 4883 3 and and CC cord-006870-f5w6fw6q 4883 4 analysis analysis NN cord-006870-f5w6fw6q 4883 5 based base VBN cord-006870-f5w6fw6q 4883 6 on on IN cord-006870-f5w6fw6q 4883 7 DSA DSA NNP cord-006870-f5w6fw6q 4883 8 perfusion perfusion NN cord-006870-f5w6fw6q 4883 9 may may MD cord-006870-f5w6fw6q 4883 10 assist assist VB cord-006870-f5w6fw6q 4883 11 with with IN cord-006870-f5w6fw6q 4883 12 real real JJ cord-006870-f5w6fw6q 4883 13 - - HYPH cord-006870-f5w6fw6q 4883 14 time time NN cord-006870-f5w6fw6q 4883 15 assessment assessment NN cord-006870-f5w6fw6q 4883 16 of of IN cord-006870-f5w6fw6q 4883 17 treatment treatment NN cord-006870-f5w6fw6q 4883 18 efficacy efficacy NN cord-006870-f5w6fw6q 4883 19 for for IN cord-006870-f5w6fw6q 4883 20 patients patient NNS cord-006870-f5w6fw6q 4883 21 undergoing undergo VBG cord-006870-f5w6fw6q 4883 22 intra intra JJ cord-006870-f5w6fw6q 4883 23 - - JJ cord-006870-f5w6fw6q 4883 24 arterial arterial JJ cord-006870-f5w6fw6q 4883 25 verapamil verapamil NN cord-006870-f5w6fw6q 4883 26 therapy therapy NN cord-006870-f5w6fw6q 4883 27 . . . cord-006870-f5w6fw6q 4884 1 We -PRON- PRP cord-006870-f5w6fw6q 4884 2 aim aim VBP cord-006870-f5w6fw6q 4884 3 to to TO cord-006870-f5w6fw6q 4884 4 characterize characterize VB cord-006870-f5w6fw6q 4884 5 the the DT cord-006870-f5w6fw6q 4884 6 clinical clinical JJ cord-006870-f5w6fw6q 4884 7 predictors predictor NNS cord-006870-f5w6fw6q 4884 8 of of IN cord-006870-f5w6fw6q 4884 9 ventriculoperitoneal ventriculoperitoneal NN cord-006870-f5w6fw6q 4884 10 shunt shunt NN cord-006870-f5w6fw6q 4884 11 ( ( -LRB- cord-006870-f5w6fw6q 4884 12 VPS VPS NNP cord-006870-f5w6fw6q 4884 13 ) ) -RRB- cord-006870-f5w6fw6q 4884 14 placement placement NN cord-006870-f5w6fw6q 4884 15 in in IN cord-006870-f5w6fw6q 4884 16 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4884 17 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4884 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4884 19 ( ( -LRB- cord-006870-f5w6fw6q 4884 20 aSAH asah JJ cord-006870-f5w6fw6q 4884 21 ) ) -RRB- cord-006870-f5w6fw6q 4884 22 patients patient NNS cord-006870-f5w6fw6q 4884 23 . . . cord-006870-f5w6fw6q 4885 1 There there EX cord-006870-f5w6fw6q 4885 2 has have VBZ cord-006870-f5w6fw6q 4885 3 been be VBN cord-006870-f5w6fw6q 4885 4 no no DT cord-006870-f5w6fw6q 4885 5 clear clear JJ cord-006870-f5w6fw6q 4885 6 consensus consensus NN cord-006870-f5w6fw6q 4885 7 as as IN cord-006870-f5w6fw6q 4885 8 to to IN cord-006870-f5w6fw6q 4885 9 effective effective JJ cord-006870-f5w6fw6q 4885 10 measures measure NNS cord-006870-f5w6fw6q 4885 11 of of IN cord-006870-f5w6fw6q 4885 12 predicting predict VBG cord-006870-f5w6fw6q 4885 13 VPS VPS NNP cord-006870-f5w6fw6q 4885 14 placement placement NN cord-006870-f5w6fw6q 4885 15 in in IN cord-006870-f5w6fw6q 4885 16 these these DT cord-006870-f5w6fw6q 4885 17 patients patient NNS cord-006870-f5w6fw6q 4885 18 . . . cord-006870-f5w6fw6q 4886 1 We -PRON- PRP cord-006870-f5w6fw6q 4886 2 reviewed review VBD cord-006870-f5w6fw6q 4886 3 the the DT cord-006870-f5w6fw6q 4886 4 clinical clinical JJ cord-006870-f5w6fw6q 4886 5 data datum NNS cord-006870-f5w6fw6q 4886 6 of of IN cord-006870-f5w6fw6q 4886 7 patients patient NNS cord-006870-f5w6fw6q 4886 8 with with IN cord-006870-f5w6fw6q 4886 9 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4886 10 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4886 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4886 12 ( ( -LRB- cord-006870-f5w6fw6q 4886 13 aSAH asah JJ cord-006870-f5w6fw6q 4886 14 ) ) -RRB- cord-006870-f5w6fw6q 4886 15 who who WP cord-006870-f5w6fw6q 4886 16 were be VBD cord-006870-f5w6fw6q 4886 17 treated treat VBN cord-006870-f5w6fw6q 4886 18 at at IN cord-006870-f5w6fw6q 4886 19 our -PRON- PRP$ cord-006870-f5w6fw6q 4886 20 institution institution NN cord-006870-f5w6fw6q 4886 21 between between IN cord-006870-f5w6fw6q 4886 22 2011 2011 CD cord-006870-f5w6fw6q 4886 23 - - SYM cord-006870-f5w6fw6q 4886 24 2014 2014 CD cord-006870-f5w6fw6q 4886 25 . . . cord-006870-f5w6fw6q 4887 1 We -PRON- PRP cord-006870-f5w6fw6q 4887 2 eliminated eliminate VBD cord-006870-f5w6fw6q 4887 3 patients patient NNS cord-006870-f5w6fw6q 4887 4 who who WP cord-006870-f5w6fw6q 4887 5 died die VBD cord-006870-f5w6fw6q 4887 6 or or CC cord-006870-f5w6fw6q 4887 7 had have VBD cord-006870-f5w6fw6q 4887 8 withdrawal withdrawal NN cord-006870-f5w6fw6q 4887 9 of of IN cord-006870-f5w6fw6q 4887 10 care care NN cord-006870-f5w6fw6q 4887 11 during during IN cord-006870-f5w6fw6q 4887 12 admission admission NN cord-006870-f5w6fw6q 4887 13 . . . cord-006870-f5w6fw6q 4888 1 We -PRON- PRP cord-006870-f5w6fw6q 4888 2 recorded record VBD cord-006870-f5w6fw6q 4888 3 patient patient JJ cord-006870-f5w6fw6q 4888 4 demographics demographic NNS cord-006870-f5w6fw6q 4888 5 and and CC cord-006870-f5w6fw6q 4888 6 clinical clinical JJ cord-006870-f5w6fw6q 4888 7 predictors predictor NNS cord-006870-f5w6fw6q 4888 8 including include VBG cord-006870-f5w6fw6q 4888 9 admission admission NN cord-006870-f5w6fw6q 4888 10 / / SYM cord-006870-f5w6fw6q 4888 11 discharge discharge NN cord-006870-f5w6fw6q 4888 12 Glasgow Glasgow NNP cord-006870-f5w6fw6q 4888 13 Coma Coma NNP cord-006870-f5w6fw6q 4888 14 Scale Scale NNP cord-006870-f5w6fw6q 4888 15 ( ( -LRB- cord-006870-f5w6fw6q 4888 16 GCS GCS NNP cord-006870-f5w6fw6q 4888 17 ) ) -RRB- cord-006870-f5w6fw6q 4888 18 , , , cord-006870-f5w6fw6q 4888 19 Hunt Hunt NNP cord-006870-f5w6fw6q 4888 20 Hess Hess NNP cord-006870-f5w6fw6q 4888 21 score score NN cord-006870-f5w6fw6q 4888 22 , , , cord-006870-f5w6fw6q 4888 23 aneurysm aneurysm NN cord-006870-f5w6fw6q 4888 24 size size NN cord-006870-f5w6fw6q 4888 25 / / SYM cord-006870-f5w6fw6q 4888 26 location location NN cord-006870-f5w6fw6q 4888 27 , , , cord-006870-f5w6fw6q 4888 28 modified modify VBN cord-006870-f5w6fw6q 4888 29 Fischer Fischer NNP cord-006870-f5w6fw6q 4888 30 score score NN cord-006870-f5w6fw6q 4888 31 , , , cord-006870-f5w6fw6q 4888 32 modified modify VBD cord-006870-f5w6fw6q 4888 33 Rankin Rankin NNP cord-006870-f5w6fw6q 4888 34 scale scale NN cord-006870-f5w6fw6q 4888 35 ( ( -LRB- cord-006870-f5w6fw6q 4888 36 mRS mRS '' cord-006870-f5w6fw6q 4888 37 ) ) -RRB- cord-006870-f5w6fw6q 4888 38 , , , cord-006870-f5w6fw6q 4888 39 intracranial intracranial JJ cord-006870-f5w6fw6q 4888 40 pressure pressure NN cord-006870-f5w6fw6q 4888 41 ( ( -LRB- cord-006870-f5w6fw6q 4888 42 ICP ICP NNP cord-006870-f5w6fw6q 4888 43 ) ) -RRB- cord-006870-f5w6fw6q 4888 44 values value NNS cord-006870-f5w6fw6q 4888 45 during during IN cord-006870-f5w6fw6q 4888 46 EVD EVD NNP cord-006870-f5w6fw6q 4888 47 clamp clamp NN cord-006870-f5w6fw6q 4888 48 trial trial NN cord-006870-f5w6fw6q 4888 49 , , , cord-006870-f5w6fw6q 4888 50 and and CC cord-006870-f5w6fw6q 4888 51 incidence incidence NN cord-006870-f5w6fw6q 4888 52 of of IN cord-006870-f5w6fw6q 4888 53 vasospasm vasospasm NN cord-006870-f5w6fw6q 4888 54 requiring require VBG cord-006870-f5w6fw6q 4888 55 intra intra JJ cord-006870-f5w6fw6q 4888 56 - - JJ cord-006870-f5w6fw6q 4888 57 arterial arterial JJ cord-006870-f5w6fw6q 4888 58 therapy therapy NN cord-006870-f5w6fw6q 4888 59 . . . cord-006870-f5w6fw6q 4889 1 There there EX cord-006870-f5w6fw6q 4889 2 were be VBD cord-006870-f5w6fw6q 4889 3 112 112 CD cord-006870-f5w6fw6q 4889 4 patients patient NNS cord-006870-f5w6fw6q 4889 5 included include VBN cord-006870-f5w6fw6q 4889 6 in in IN cord-006870-f5w6fw6q 4889 7 this this DT cord-006870-f5w6fw6q 4889 8 study study NN cord-006870-f5w6fw6q 4889 9 and and CC cord-006870-f5w6fw6q 4889 10 36 36 CD cord-006870-f5w6fw6q 4889 11 % % NN cord-006870-f5w6fw6q 4889 12 of of IN cord-006870-f5w6fw6q 4889 13 patients patient NNS cord-006870-f5w6fw6q 4889 14 required require VBN cord-006870-f5w6fw6q 4889 15 VPS VPS NNP cord-006870-f5w6fw6q 4889 16 ( ( -LRB- cord-006870-f5w6fw6q 4889 17 n=42/112 n=42/112 NNP cord-006870-f5w6fw6q 4889 18 ) ) -RRB- cord-006870-f5w6fw6q 4889 19 . . . cord-006870-f5w6fw6q 4890 1 VPS VPS NNP cord-006870-f5w6fw6q 4890 2 patients patient NNS cord-006870-f5w6fw6q 4890 3 had have VBD cord-006870-f5w6fw6q 4890 4 significantly significantly RB cord-006870-f5w6fw6q 4890 5 worse bad JJR cord-006870-f5w6fw6q 4890 6 mRS mrs IN cord-006870-f5w6fw6q 4890 7 functional functional JJ cord-006870-f5w6fw6q 4890 8 scores score NNS cord-006870-f5w6fw6q 4890 9 at at IN cord-006870-f5w6fw6q 4890 10 discharge discharge NN cord-006870-f5w6fw6q 4890 11 ( ( -LRB- cord-006870-f5w6fw6q 4890 12 2.7 2.7 CD cord-006870-f5w6fw6q 4890 13 vs vs IN cord-006870-f5w6fw6q 4890 14 3.4 3.4 CD cord-006870-f5w6fw6q 4890 15 ; ; : cord-006870-f5w6fw6q 4890 16 p=0.029 p=0.029 NNP cord-006870-f5w6fw6q 4890 17 ) ) -RRB- cord-006870-f5w6fw6q 4890 18 , , , cord-006870-f5w6fw6q 4890 19 but but CC cord-006870-f5w6fw6q 4890 20 this this DT cord-006870-f5w6fw6q 4890 21 began begin VBD cord-006870-f5w6fw6q 4890 22 to to TO cord-006870-f5w6fw6q 4890 23 balance balance VB cord-006870-f5w6fw6q 4890 24 at at IN cord-006870-f5w6fw6q 4890 25 1 1 CD cord-006870-f5w6fw6q 4890 26 year year NN cord-006870-f5w6fw6q 4890 27 ( ( -LRB- cord-006870-f5w6fw6q 4890 28 2.5 2.5 CD cord-006870-f5w6fw6q 4890 29 vs vs IN cord-006870-f5w6fw6q 4890 30 3.3 3.3 CD cord-006870-f5w6fw6q 4890 31 ; ; : cord-006870-f5w6fw6q 4890 32 p=0.08 p=0.08 NNP cord-006870-f5w6fw6q 4890 33 ) ) -RRB- cord-006870-f5w6fw6q 4890 34 . . . cord-006870-f5w6fw6q 4891 1 Aneurysms aneurysm NNS cord-006870-f5w6fw6q 4891 2 were be VBD cord-006870-f5w6fw6q 4891 3 significantly significantly RB cord-006870-f5w6fw6q 4891 4 larger large JJR cord-006870-f5w6fw6q 4891 5 in in IN cord-006870-f5w6fw6q 4891 6 VPS VPS NNP cord-006870-f5w6fw6q 4891 7 patients patient NNS cord-006870-f5w6fw6q 4891 8 ( ( -LRB- cord-006870-f5w6fw6q 4891 9 7.4 7.4 CD cord-006870-f5w6fw6q 4891 10 cm cm NNS cord-006870-f5w6fw6q 4891 11 vs vs IN cord-006870-f5w6fw6q 4891 12 5.5 5.5 CD cord-006870-f5w6fw6q 4891 13 cm cm NNS cord-006870-f5w6fw6q 4891 14 ; ; : cord-006870-f5w6fw6q 4891 15 CI ci NN cord-006870-f5w6fw6q 4891 16 : : : cord-006870-f5w6fw6q 4891 17 0.57 0.57 CD cord-006870-f5w6fw6q 4891 18 to to IN cord-006870-f5w6fw6q 4891 19 3.38 3.38 CD cord-006870-f5w6fw6q 4891 20 ; ; : cord-006870-f5w6fw6q 4891 21 p=0.006 p=0.006 NNS cord-006870-f5w6fw6q 4891 22 ) ) -RRB- cord-006870-f5w6fw6q 4891 23 . . . cord-006870-f5w6fw6q 4892 1 A a DT cord-006870-f5w6fw6q 4892 2 greater great JJR cord-006870-f5w6fw6q 4892 3 percentage percentage NN cord-006870-f5w6fw6q 4892 4 of of IN cord-006870-f5w6fw6q 4892 5 VPS VPS NNP cord-006870-f5w6fw6q 4892 6 patients patient NNS cord-006870-f5w6fw6q 4892 7 had have VBD cord-006870-f5w6fw6q 4892 8 posterior posterior JJ cord-006870-f5w6fw6q 4892 9 fossa fossa NN cord-006870-f5w6fw6q 4892 10 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4892 11 , , , cord-006870-f5w6fw6q 4892 12 but but CC cord-006870-f5w6fw6q 4892 13 this this DT cord-006870-f5w6fw6q 4892 14 was be VBD cord-006870-f5w6fw6q 4892 15 not not RB cord-006870-f5w6fw6q 4892 16 found find VBN cord-006870-f5w6fw6q 4892 17 to to TO cord-006870-f5w6fw6q 4892 18 be be VB cord-006870-f5w6fw6q 4892 19 statistically statistically RB cord-006870-f5w6fw6q 4892 20 significant significant JJ cord-006870-f5w6fw6q 4892 21 ( ( -LRB- cord-006870-f5w6fw6q 4892 22 37 37 CD cord-006870-f5w6fw6q 4892 23 % % NN cord-006870-f5w6fw6q 4892 24 vs vs IN cord-006870-f5w6fw6q 4892 25 52 52 CD cord-006870-f5w6fw6q 4892 26 % % NN cord-006870-f5w6fw6q 4892 27 ; ; : cord-006870-f5w6fw6q 4892 28 p=0.12 p=0.12 NN cord-006870-f5w6fw6q 4892 29 ) ) -RRB- cord-006870-f5w6fw6q 4892 30 . . . cord-006870-f5w6fw6q 4893 1 VPS VPS NNP cord-006870-f5w6fw6q 4893 2 patients patient NNS cord-006870-f5w6fw6q 4893 3 had have VBD cord-006870-f5w6fw6q 4893 4 significantly significantly RB cord-006870-f5w6fw6q 4893 5 lower low JJR cord-006870-f5w6fw6q 4893 6 GCS GCS NNP cord-006870-f5w6fw6q 4893 7 scores score NNS cord-006870-f5w6fw6q 4893 8 at at IN cord-006870-f5w6fw6q 4893 9 admission admission NN cord-006870-f5w6fw6q 4893 10 ( ( -LRB- cord-006870-f5w6fw6q 4893 11 12.9 12.9 CD cord-006870-f5w6fw6q 4893 12 vs vs IN cord-006870-f5w6fw6q 4893 13 14.1 14.1 CD cord-006870-f5w6fw6q 4893 14 ; ; : cord-006870-f5w6fw6q 4893 15 p=0.02 p=0.02 NNP cord-006870-f5w6fw6q 4893 16 ) ) -RRB- cord-006870-f5w6fw6q 4893 17 , , , cord-006870-f5w6fw6q 4893 18 and and CC cord-006870-f5w6fw6q 4893 19 discharge discharge NN cord-006870-f5w6fw6q 4893 20 ( ( -LRB- cord-006870-f5w6fw6q 4893 21 11.7 11.7 CD cord-006870-f5w6fw6q 4893 22 vs vs IN cord-006870-f5w6fw6q 4893 23 9.4 9.4 CD cord-006870-f5w6fw6q 4893 24 ; ; : cord-006870-f5w6fw6q 4893 25 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 4893 26 ) ) -RRB- cord-006870-f5w6fw6q 4893 27 . . . cord-006870-f5w6fw6q 4894 1 There there EX cord-006870-f5w6fw6q 4894 2 was be VBD cord-006870-f5w6fw6q 4894 3 no no DT cord-006870-f5w6fw6q 4894 4 difference difference NN cord-006870-f5w6fw6q 4894 5 in in IN cord-006870-f5w6fw6q 4894 6 modified modify VBN cord-006870-f5w6fw6q 4894 7 Fischer Fischer NNP cord-006870-f5w6fw6q 4894 8 score score NN cord-006870-f5w6fw6q 4894 9 ( ( -LRB- cord-006870-f5w6fw6q 4894 10 p=0.36 p=0.36 NN cord-006870-f5w6fw6q 4894 11 ) ) -RRB- cord-006870-f5w6fw6q 4894 12 or or CC cord-006870-f5w6fw6q 4894 13 Hunt Hunt NNP cord-006870-f5w6fw6q 4894 14 Hess Hess NNP cord-006870-f5w6fw6q 4894 15 ( ( -LRB- cord-006870-f5w6fw6q 4894 16 p=0.06 p=0.06 NNP cord-006870-f5w6fw6q 4894 17 ) ) -RRB- cord-006870-f5w6fw6q 4894 18 , , , cord-006870-f5w6fw6q 4894 19 but but CC cord-006870-f5w6fw6q 4894 20 both both DT cord-006870-f5w6fw6q 4894 21 variables variable NNS cord-006870-f5w6fw6q 4894 22 were be VBD cord-006870-f5w6fw6q 4894 23 higher high JJR cord-006870-f5w6fw6q 4894 24 in in IN cord-006870-f5w6fw6q 4894 25 the the DT cord-006870-f5w6fw6q 4894 26 VPS VPS NNP cord-006870-f5w6fw6q 4894 27 cohort cohort NN cord-006870-f5w6fw6q 4894 28 . . . cord-006870-f5w6fw6q 4895 1 There there EX cord-006870-f5w6fw6q 4895 2 was be VBD cord-006870-f5w6fw6q 4895 3 no no DT cord-006870-f5w6fw6q 4895 4 difference difference NN cord-006870-f5w6fw6q 4895 5 in in IN cord-006870-f5w6fw6q 4895 6 the the DT cord-006870-f5w6fw6q 4895 7 frequency frequency NN cord-006870-f5w6fw6q 4895 8 of of IN cord-006870-f5w6fw6q 4895 9 vasospasm vasospasm NN cord-006870-f5w6fw6q 4895 10 in in IN cord-006870-f5w6fw6q 4895 11 the the DT cord-006870-f5w6fw6q 4895 12 VPS VPS NNP cord-006870-f5w6fw6q 4895 13 cohort cohort NN cord-006870-f5w6fw6q 4895 14 ( ( -LRB- cord-006870-f5w6fw6q 4895 15 p=1.0 p=1.0 NNP cord-006870-f5w6fw6q 4895 16 ) ) -RRB- cord-006870-f5w6fw6q 4895 17 , , , cord-006870-f5w6fw6q 4895 18 or or CC cord-006870-f5w6fw6q 4895 19 ICP ICP NNP cord-006870-f5w6fw6q 4895 20 values value NNS cord-006870-f5w6fw6q 4895 21 ( ( -LRB- cord-006870-f5w6fw6q 4895 22 p=0.15 p=0.15 NNP cord-006870-f5w6fw6q 4895 23 ) ) -RRB- cord-006870-f5w6fw6q 4895 24 . . . cord-006870-f5w6fw6q 4896 1 Patients patient NNS cord-006870-f5w6fw6q 4896 2 presenting present VBG cord-006870-f5w6fw6q 4896 3 with with IN cord-006870-f5w6fw6q 4896 4 large large JJ cord-006870-f5w6fw6q 4896 5 aneurysms aneurysm NNS cord-006870-f5w6fw6q 4896 6 and and CC cord-006870-f5w6fw6q 4896 7 poor poor JJ cord-006870-f5w6fw6q 4896 8 GCS GCS NNP cord-006870-f5w6fw6q 4896 9 scores score NNS cord-006870-f5w6fw6q 4896 10 had have VBD cord-006870-f5w6fw6q 4896 11 a a DT cord-006870-f5w6fw6q 4896 12 significantly significantly RB cord-006870-f5w6fw6q 4896 13 higher high JJR cord-006870-f5w6fw6q 4896 14 likelihood likelihood NN cord-006870-f5w6fw6q 4896 15 of of IN cord-006870-f5w6fw6q 4896 16 requiring require VBG cord-006870-f5w6fw6q 4896 17 VPS VPS NNP cord-006870-f5w6fw6q 4896 18 during during IN cord-006870-f5w6fw6q 4896 19 admission admission NN cord-006870-f5w6fw6q 4896 20 . . . cord-006870-f5w6fw6q 4897 1 These these DT cord-006870-f5w6fw6q 4897 2 patients patient NNS cord-006870-f5w6fw6q 4897 3 had have VBD cord-006870-f5w6fw6q 4897 4 significantly significantly RB cord-006870-f5w6fw6q 4897 5 poorer poor JJR cord-006870-f5w6fw6q 4897 6 mRS mrs PRP$ cord-006870-f5w6fw6q 4897 7 scores score NNS cord-006870-f5w6fw6q 4897 8 at at IN cord-006870-f5w6fw6q 4897 9 discharge discharge NN cord-006870-f5w6fw6q 4897 10 but but CC cord-006870-f5w6fw6q 4897 11 not not RB cord-006870-f5w6fw6q 4897 12 at at IN cord-006870-f5w6fw6q 4897 13 1 1 CD cord-006870-f5w6fw6q 4897 14 year year NN cord-006870-f5w6fw6q 4897 15 . . . cord-006870-f5w6fw6q 4898 1 Subarachnoid subarachnoid IN cord-006870-f5w6fw6q 4898 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4898 3 ( ( -LRB- cord-006870-f5w6fw6q 4898 4 SAH SAH NNP cord-006870-f5w6fw6q 4898 5 ) ) -RRB- cord-006870-f5w6fw6q 4898 6 affects affect VBZ cord-006870-f5w6fw6q 4898 7 a a DT cord-006870-f5w6fw6q 4898 8 young young JJ cord-006870-f5w6fw6q 4898 9 population population NN cord-006870-f5w6fw6q 4898 10 and and CC cord-006870-f5w6fw6q 4898 11 results result NNS cord-006870-f5w6fw6q 4898 12 in in IN cord-006870-f5w6fw6q 4898 13 death death NN cord-006870-f5w6fw6q 4898 14 or or CC cord-006870-f5w6fw6q 4898 15 disability disability NN cord-006870-f5w6fw6q 4898 16 in in IN cord-006870-f5w6fw6q 4898 17 the the DT cord-006870-f5w6fw6q 4898 18 majority majority NN cord-006870-f5w6fw6q 4898 19 of of IN cord-006870-f5w6fw6q 4898 20 those those DT cord-006870-f5w6fw6q 4898 21 who who WP cord-006870-f5w6fw6q 4898 22 experience experience VBP cord-006870-f5w6fw6q 4898 23 it -PRON- PRP cord-006870-f5w6fw6q 4898 24 . . . cord-006870-f5w6fw6q 4899 1 This this DT cord-006870-f5w6fw6q 4899 2 epidemiology epidemiology NN cord-006870-f5w6fw6q 4899 3 is be VBZ cord-006870-f5w6fw6q 4899 4 very very RB cord-006870-f5w6fw6q 4899 5 different different JJ cord-006870-f5w6fw6q 4899 6 from from IN cord-006870-f5w6fw6q 4899 7 other other JJ cord-006870-f5w6fw6q 4899 8 forms form NNS cord-006870-f5w6fw6q 4899 9 of of IN cord-006870-f5w6fw6q 4899 10 stroke stroke NN cord-006870-f5w6fw6q 4899 11 . . . cord-006870-f5w6fw6q 4900 1 Consequently consequently RB cord-006870-f5w6fw6q 4900 2 , , , cord-006870-f5w6fw6q 4900 3 patients patient NNS cord-006870-f5w6fw6q 4900 4 with with IN cord-006870-f5w6fw6q 4900 5 SAH SAH NNP cord-006870-f5w6fw6q 4900 6 and and CC cord-006870-f5w6fw6q 4900 7 their -PRON- PRP$ cord-006870-f5w6fw6q 4900 8 families family NNS cord-006870-f5w6fw6q 4900 9 may may MD cord-006870-f5w6fw6q 4900 10 have have VB cord-006870-f5w6fw6q 4900 11 different different JJ cord-006870-f5w6fw6q 4900 12 priorities priority NNS cord-006870-f5w6fw6q 4900 13 for for IN cord-006870-f5w6fw6q 4900 14 recovery recovery NN cord-006870-f5w6fw6q 4900 15 . . . cord-006870-f5w6fw6q 4901 1 Involving involve VBG cord-006870-f5w6fw6q 4901 2 patient patient JJ cord-006870-f5w6fw6q 4901 3 perspectives perspective NNS cord-006870-f5w6fw6q 4901 4 is be VBZ cord-006870-f5w6fw6q 4901 5 encouraged encourage VBN cord-006870-f5w6fw6q 4901 6 in in IN cord-006870-f5w6fw6q 4901 7 research research NN cord-006870-f5w6fw6q 4901 8 and and CC cord-006870-f5w6fw6q 4901 9 is be VBZ cord-006870-f5w6fw6q 4901 10 often often RB cord-006870-f5w6fw6q 4901 11 accomplished accomplish VBN cord-006870-f5w6fw6q 4901 12 using use VBG cord-006870-f5w6fw6q 4901 13 patient patient NN cord-006870-f5w6fw6q 4901 14 - - HYPH cord-006870-f5w6fw6q 4901 15 reported report VBN cord-006870-f5w6fw6q 4901 16 outcome outcome NN cord-006870-f5w6fw6q 4901 17 measures measure NNS cord-006870-f5w6fw6q 4901 18 ( ( -LRB- cord-006870-f5w6fw6q 4901 19 PROMs prom NNS cord-006870-f5w6fw6q 4901 20 ) ) -RRB- cord-006870-f5w6fw6q 4901 21 . . . cord-006870-f5w6fw6q 4902 1 However however RB cord-006870-f5w6fw6q 4902 2 , , , cord-006870-f5w6fw6q 4902 3 whether whether IN cord-006870-f5w6fw6q 4902 4 PROMs prom NNS cord-006870-f5w6fw6q 4902 5 reflect reflect VBP cord-006870-f5w6fw6q 4902 6 patient patient JJ cord-006870-f5w6fw6q 4902 7 and and CC cord-006870-f5w6fw6q 4902 8 family family NN cord-006870-f5w6fw6q 4902 9 priorities priority NNS cord-006870-f5w6fw6q 4902 10 is be VBZ cord-006870-f5w6fw6q 4902 11 unclear unclear JJ cord-006870-f5w6fw6q 4902 12 given give VBN cord-006870-f5w6fw6q 4902 13 that that DT cord-006870-f5w6fw6q 4902 14 ( ( -LRB- cord-006870-f5w6fw6q 4902 15 a a LS cord-006870-f5w6fw6q 4902 16 ) ) -RRB- cord-006870-f5w6fw6q 4902 17 PROMs prom NNS cord-006870-f5w6fw6q 4902 18 are be VBP cord-006870-f5w6fw6q 4902 19 often often RB cord-006870-f5w6fw6q 4902 20 developed develop VBN cord-006870-f5w6fw6q 4902 21 without without IN cord-006870-f5w6fw6q 4902 22 their -PRON- PRP$ cord-006870-f5w6fw6q 4902 23 input input NN cord-006870-f5w6fw6q 4902 24 ; ; : cord-006870-f5w6fw6q 4902 25 and and CC cord-006870-f5w6fw6q 4902 26 ( ( -LRB- cord-006870-f5w6fw6q 4902 27 b b LS cord-006870-f5w6fw6q 4902 28 ) ) -RRB- cord-006870-f5w6fw6q 4902 29 generic generic JJ cord-006870-f5w6fw6q 4902 30 PROMs prom NNS cord-006870-f5w6fw6q 4902 31 may may MD cord-006870-f5w6fw6q 4902 32 not not RB cord-006870-f5w6fw6q 4902 33 apply apply VB cord-006870-f5w6fw6q 4902 34 to to IN cord-006870-f5w6fw6q 4902 35 specific specific JJ cord-006870-f5w6fw6q 4902 36 conditions condition NNS cord-006870-f5w6fw6q 4902 37 . . . cord-006870-f5w6fw6q 4903 1 We -PRON- PRP cord-006870-f5w6fw6q 4903 2 aimed aim VBD cord-006870-f5w6fw6q 4903 3 to to TO cord-006870-f5w6fw6q 4903 4 systematically systematically RB cord-006870-f5w6fw6q 4903 5 review review VB cord-006870-f5w6fw6q 4903 6 the the DT cord-006870-f5w6fw6q 4903 7 SAH SAH NNP cord-006870-f5w6fw6q 4903 8 literature literature NN cord-006870-f5w6fw6q 4903 9 that that WDT cord-006870-f5w6fw6q 4903 10 has have VBZ cord-006870-f5w6fw6q 4903 11 : : : cord-006870-f5w6fw6q 4903 12 a a LS cord-006870-f5w6fw6q 4903 13 ) ) -RRB- cord-006870-f5w6fw6q 4904 1 involved involve VBN cord-006870-f5w6fw6q 4904 2 patient patient JJ cord-006870-f5w6fw6q 4904 3 , , , cord-006870-f5w6fw6q 4904 4 family family NN cord-006870-f5w6fw6q 4904 5 or or CC cord-006870-f5w6fw6q 4904 6 caregivers caregiver NNS cord-006870-f5w6fw6q 4904 7 in in IN cord-006870-f5w6fw6q 4904 8 evaluating evaluate VBG cord-006870-f5w6fw6q 4904 9 existing exist VBG cord-006870-f5w6fw6q 4904 10 outcome outcome NN cord-006870-f5w6fw6q 4904 11 measures measure NNS cord-006870-f5w6fw6q 4904 12 , , , cord-006870-f5w6fw6q 4905 1 b b LS cord-006870-f5w6fw6q 4905 2 ) ) -RRB- cord-006870-f5w6fw6q 4905 3 developed develop VBD cord-006870-f5w6fw6q 4905 4 novel novel JJ cord-006870-f5w6fw6q 4905 5 outcome outcome NN cord-006870-f5w6fw6q 4905 6 measures measure NNS cord-006870-f5w6fw6q 4905 7 by by IN cord-006870-f5w6fw6q 4905 8 incorporating incorporate VBG cord-006870-f5w6fw6q 4905 9 their -PRON- PRP$ cord-006870-f5w6fw6q 4905 10 perspectives perspective NNS cord-006870-f5w6fw6q 4905 11 ( ( -LRB- cord-006870-f5w6fw6q 4905 12 including include VBG cord-006870-f5w6fw6q 4905 13 co co NN cord-006870-f5w6fw6q 4905 14 - - JJ cord-006870-f5w6fw6q 4905 15 development development JJ cord-006870-f5w6fw6q 4905 16 ) ) -RRB- cord-006870-f5w6fw6q 4905 17 , , , cord-006870-f5w6fw6q 4905 18 or or CC cord-006870-f5w6fw6q 4905 19 c c NN cord-006870-f5w6fw6q 4905 20 ) ) -RRB- cord-006870-f5w6fw6q 4905 21 described describe VBN cord-006870-f5w6fw6q 4905 22 outcomes outcome NNS cord-006870-f5w6fw6q 4905 23 important important JJ cord-006870-f5w6fw6q 4905 24 to to IN cord-006870-f5w6fw6q 4905 25 patients patient NNS cord-006870-f5w6fw6q 4905 26 , , , cord-006870-f5w6fw6q 4905 27 families family NNS cord-006870-f5w6fw6q 4905 28 , , , cord-006870-f5w6fw6q 4905 29 or or CC cord-006870-f5w6fw6q 4905 30 caregivers caregiver NNS cord-006870-f5w6fw6q 4905 31 . . . cord-006870-f5w6fw6q 4906 1 We -PRON- PRP cord-006870-f5w6fw6q 4906 2 searched search VBD cord-006870-f5w6fw6q 4906 3 Embase Embase NNP cord-006870-f5w6fw6q 4906 4 and and CC cord-006870-f5w6fw6q 4906 5 Ovid Ovid NNP cord-006870-f5w6fw6q 4906 6 MEDLINE MEDLINE NNP cord-006870-f5w6fw6q 4906 7 from from IN cord-006870-f5w6fw6q 4906 8 inception inception NN cord-006870-f5w6fw6q 4906 9 to to IN cord-006870-f5w6fw6q 4906 10 December December NNP cord-006870-f5w6fw6q 4906 11 19 19 CD cord-006870-f5w6fw6q 4906 12 , , , cord-006870-f5w6fw6q 4906 13 2016 2016 CD cord-006870-f5w6fw6q 4906 14 . . . cord-006870-f5w6fw6q 4907 1 Study study NN cord-006870-f5w6fw6q 4907 2 eligibility eligibility NN cord-006870-f5w6fw6q 4907 3 and and CC cord-006870-f5w6fw6q 4907 4 data datum NNS cord-006870-f5w6fw6q 4907 5 extraction extraction NN cord-006870-f5w6fw6q 4907 6 was be VBD cord-006870-f5w6fw6q 4907 7 performed perform VBN cord-006870-f5w6fw6q 4907 8 independently independently RB cord-006870-f5w6fw6q 4907 9 and and CC cord-006870-f5w6fw6q 4907 10 in in IN cord-006870-f5w6fw6q 4907 11 duplicate duplicate NN cord-006870-f5w6fw6q 4907 12 . . . cord-006870-f5w6fw6q 4908 1 For for IN cord-006870-f5w6fw6q 4908 2 each each DT cord-006870-f5w6fw6q 4908 3 eligible eligible JJ cord-006870-f5w6fw6q 4908 4 citation citation NN cord-006870-f5w6fw6q 4908 5 , , , cord-006870-f5w6fw6q 4908 6 we -PRON- PRP cord-006870-f5w6fw6q 4908 7 abstracted abstract VBD cord-006870-f5w6fw6q 4908 8 the the DT cord-006870-f5w6fw6q 4908 9 following follow VBG cord-006870-f5w6fw6q 4908 10 : : : cord-006870-f5w6fw6q 4908 11 study study NN cord-006870-f5w6fw6q 4908 12 population population NN cord-006870-f5w6fw6q 4908 13 , , , cord-006870-f5w6fw6q 4908 14 design design NN cord-006870-f5w6fw6q 4908 15 , , , cord-006870-f5w6fw6q 4908 16 type type NN cord-006870-f5w6fw6q 4908 17 of of IN cord-006870-f5w6fw6q 4908 18 patient patient JJ cord-006870-f5w6fw6q 4908 19 involvement involvement NN cord-006870-f5w6fw6q 4908 20 , , , cord-006870-f5w6fw6q 4908 21 and and CC cord-006870-f5w6fw6q 4908 22 outcome outcome NN cord-006870-f5w6fw6q 4908 23 measure(s measure(s NN cord-006870-f5w6fw6q 4908 24 ) ) -RRB- cord-006870-f5w6fw6q 4908 25 , , , cord-006870-f5w6fw6q 4908 26 as as IN cord-006870-f5w6fw6q 4908 27 applicable applicable JJ cord-006870-f5w6fw6q 4908 28 . . . cord-006870-f5w6fw6q 4909 1 We -PRON- PRP cord-006870-f5w6fw6q 4909 2 planned plan VBD cord-006870-f5w6fw6q 4909 3 a a DT cord-006870-f5w6fw6q 4909 4 qualitative qualitative JJ cord-006870-f5w6fw6q 4909 5 summary summary NN cord-006870-f5w6fw6q 4909 6 of of IN cord-006870-f5w6fw6q 4909 7 all all DT cord-006870-f5w6fw6q 4909 8 included include VBN cord-006870-f5w6fw6q 4909 9 studies study NNS cord-006870-f5w6fw6q 4909 10 . . . cord-006870-f5w6fw6q 4910 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 4910 2 search search NN cord-006870-f5w6fw6q 4910 3 yielded yield VBD cord-006870-f5w6fw6q 4910 4 4275 4275 CD cord-006870-f5w6fw6q 4910 5 unique unique JJ cord-006870-f5w6fw6q 4910 6 citations citation NNS cord-006870-f5w6fw6q 4910 7 . . . cord-006870-f5w6fw6q 4911 1 Only only RB cord-006870-f5w6fw6q 4911 2 four four CD cord-006870-f5w6fw6q 4911 3 articles article NNS cord-006870-f5w6fw6q 4911 4 have have VBP cord-006870-f5w6fw6q 4911 5 met meet VBN cord-006870-f5w6fw6q 4911 6 our -PRON- PRP$ cord-006870-f5w6fw6q 4911 7 eligibility eligibility NN cord-006870-f5w6fw6q 4911 8 criteria criterion NNS cord-006870-f5w6fw6q 4911 9 . . . cord-006870-f5w6fw6q 4912 1 In in IN cord-006870-f5w6fw6q 4912 2 each each DT cord-006870-f5w6fw6q 4912 3 , , , cord-006870-f5w6fw6q 4912 4 patients patient NNS cord-006870-f5w6fw6q 4912 5 ( ( -LRB- cord-006870-f5w6fw6q 4912 6 N=235 N=235 NNP cord-006870-f5w6fw6q 4912 7 ) ) -RRB- cord-006870-f5w6fw6q 4912 8 self self NN cord-006870-f5w6fw6q 4912 9 - - HYPH cord-006870-f5w6fw6q 4912 10 report report NN cord-006870-f5w6fw6q 4912 11 impairments impairment NNS cord-006870-f5w6fw6q 4912 12 resulting result VBG cord-006870-f5w6fw6q 4912 13 from from IN cord-006870-f5w6fw6q 4912 14 SAH SAH NNP cord-006870-f5w6fw6q 4912 15 and and CC cord-006870-f5w6fw6q 4912 16 their -PRON- PRP$ cord-006870-f5w6fw6q 4912 17 impact impact NN cord-006870-f5w6fw6q 4912 18 on on IN cord-006870-f5w6fw6q 4912 19 their -PRON- PRP$ cord-006870-f5w6fw6q 4912 20 lives life NNS cord-006870-f5w6fw6q 4912 21 ( ( -LRB- cord-006870-f5w6fw6q 4912 22 aim aim NNP cord-006870-f5w6fw6q 4912 23 c c NNP cord-006870-f5w6fw6q 4912 24 ) ) -RRB- cord-006870-f5w6fw6q 4912 25 . . . cord-006870-f5w6fw6q 4913 1 None none NN cord-006870-f5w6fw6q 4913 2 involve involve VBP cord-006870-f5w6fw6q 4913 3 the the DT cord-006870-f5w6fw6q 4913 4 evaluation evaluation NN cord-006870-f5w6fw6q 4913 5 of of IN cord-006870-f5w6fw6q 4913 6 PROM prom NN cord-006870-f5w6fw6q 4913 7 applicability applicability NN cord-006870-f5w6fw6q 4913 8 . . . cord-006870-f5w6fw6q 4914 1 Additionally additionally RB cord-006870-f5w6fw6q 4914 2 , , , cord-006870-f5w6fw6q 4914 3 we -PRON- PRP cord-006870-f5w6fw6q 4914 4 found find VBD cord-006870-f5w6fw6q 4914 5 8 8 CD cord-006870-f5w6fw6q 4914 6 articles article NNS cord-006870-f5w6fw6q 4914 7 that that WDT cord-006870-f5w6fw6q 4914 8 , , , cord-006870-f5w6fw6q 4914 9 although although IN cord-006870-f5w6fw6q 4914 10 they -PRON- PRP cord-006870-f5w6fw6q 4914 11 did do VBD cord-006870-f5w6fw6q 4914 12 not not RB cord-006870-f5w6fw6q 4914 13 meet meet VB cord-006870-f5w6fw6q 4914 14 our -PRON- PRP$ cord-006870-f5w6fw6q 4914 15 a a DT cord-006870-f5w6fw6q 4914 16 priori priori FW cord-006870-f5w6fw6q 4914 17 eligibility eligibility NN cord-006870-f5w6fw6q 4914 18 criteria criterion NNS cord-006870-f5w6fw6q 4914 19 , , , cord-006870-f5w6fw6q 4914 20 discuss discuss VB cord-006870-f5w6fw6q 4914 21 collecting collect VBG cord-006870-f5w6fw6q 4914 22 PROMs prom NNS cord-006870-f5w6fw6q 4914 23 ( ( -LRB- cord-006870-f5w6fw6q 4914 24 N=2 N=2 NNP cord-006870-f5w6fw6q 4914 25 ) ) -RRB- cord-006870-f5w6fw6q 4914 26 , , , cord-006870-f5w6fw6q 4914 27 using use VBG cord-006870-f5w6fw6q 4914 28 PROMs prom NNS cord-006870-f5w6fw6q 4914 29 to to TO cord-006870-f5w6fw6q 4914 30 predict predict VB cord-006870-f5w6fw6q 4914 31 health health NN cord-006870-f5w6fw6q 4914 32 outcomes outcome NNS cord-006870-f5w6fw6q 4914 33 ( ( -LRB- cord-006870-f5w6fw6q 4914 34 N=4 N=4 NNP cord-006870-f5w6fw6q 4914 35 ) ) -RRB- cord-006870-f5w6fw6q 4914 36 , , , cord-006870-f5w6fw6q 4914 37 and and CC cord-006870-f5w6fw6q 4914 38 comparing compare VBG cord-006870-f5w6fw6q 4914 39 PROM prom NN cord-006870-f5w6fw6q 4914 40 applicability applicability NN cord-006870-f5w6fw6q 4914 41 without without IN cord-006870-f5w6fw6q 4914 42 patient patient JJ cord-006870-f5w6fw6q 4914 43 perspectives perspective NNS cord-006870-f5w6fw6q 4914 44 ( ( -LRB- cord-006870-f5w6fw6q 4914 45 N=2 N=2 NNP cord-006870-f5w6fw6q 4914 46 ) ) -RRB- cord-006870-f5w6fw6q 4914 47 in in IN cord-006870-f5w6fw6q 4914 48 SAH SAH NNP cord-006870-f5w6fw6q 4914 49 populations population NNS cord-006870-f5w6fw6q 4914 50 . . . cord-006870-f5w6fw6q 4915 1 Based base VBN cord-006870-f5w6fw6q 4915 2 on on IN cord-006870-f5w6fw6q 4915 3 our -PRON- PRP$ cord-006870-f5w6fw6q 4915 4 findings finding NNS cord-006870-f5w6fw6q 4915 5 , , , cord-006870-f5w6fw6q 4915 6 there there EX cord-006870-f5w6fw6q 4915 7 is be VBZ cord-006870-f5w6fw6q 4915 8 alack alack , cord-006870-f5w6fw6q 4915 9 of of IN cord-006870-f5w6fw6q 4915 10 patient patient NN cord-006870-f5w6fw6q 4915 11 , , , cord-006870-f5w6fw6q 4915 12 family family NN cord-006870-f5w6fw6q 4915 13 , , , cord-006870-f5w6fw6q 4915 14 or or CC cord-006870-f5w6fw6q 4915 15 caregiver caregiver NN cord-006870-f5w6fw6q 4915 16 involvement involvement NN cord-006870-f5w6fw6q 4915 17 in in IN cord-006870-f5w6fw6q 4915 18 selecting select VBG cord-006870-f5w6fw6q 4915 19 or or CC cord-006870-f5w6fw6q 4915 20 identifying identify VBG cord-006870-f5w6fw6q 4915 21 outcomes outcome NNS cord-006870-f5w6fw6q 4915 22 after after IN cord-006870-f5w6fw6q 4915 23 SAH SAH NNP cord-006870-f5w6fw6q 4915 24 with with IN cord-006870-f5w6fw6q 4915 25 direct direct JJ cord-006870-f5w6fw6q 4915 26 relevance relevance NN cord-006870-f5w6fw6q 4915 27 to to IN cord-006870-f5w6fw6q 4915 28 them -PRON- PRP cord-006870-f5w6fw6q 4915 29 . . . cord-006870-f5w6fw6q 4916 1 SAH SAH NNP cord-006870-f5w6fw6q 4916 2 research research NN cord-006870-f5w6fw6q 4916 3 may may MD cord-006870-f5w6fw6q 4916 4 be be VB cord-006870-f5w6fw6q 4916 5 overlooking overlook VBG cord-006870-f5w6fw6q 4916 6 outcomes outcome NNS cord-006870-f5w6fw6q 4916 7 that that WDT cord-006870-f5w6fw6q 4916 8 are be VBP cord-006870-f5w6fw6q 4916 9 important important JJ cord-006870-f5w6fw6q 4916 10 to to IN cord-006870-f5w6fw6q 4916 11 patients patient NNS cord-006870-f5w6fw6q 4916 12 . . . cord-006870-f5w6fw6q 4917 1 Early early JJ cord-006870-f5w6fw6q 4917 2 brain brain NN cord-006870-f5w6fw6q 4917 3 injury injury NN cord-006870-f5w6fw6q 4917 4 ( ( -LRB- cord-006870-f5w6fw6q 4917 5 EBI EBI NNP cord-006870-f5w6fw6q 4917 6 ) ) -RRB- cord-006870-f5w6fw6q 4917 7 after after IN cord-006870-f5w6fw6q 4917 8 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4917 9 subarachnoid subarachnoid NNP cord-006870-f5w6fw6q 4917 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4917 11 ( ( -LRB- cord-006870-f5w6fw6q 4917 12 aSAH aSAH NNP cord-006870-f5w6fw6q 4917 13 ) ) -RRB- cord-006870-f5w6fw6q 4917 14 is be VBZ cord-006870-f5w6fw6q 4917 15 defined define VBN cord-006870-f5w6fw6q 4917 16 as as IN cord-006870-f5w6fw6q 4917 17 brain brain NN cord-006870-f5w6fw6q 4917 18 injury injury NN cord-006870-f5w6fw6q 4917 19 occurring occur VBG cord-006870-f5w6fw6q 4917 20 within within IN cord-006870-f5w6fw6q 4917 21 72 72 CD cord-006870-f5w6fw6q 4917 22 hours hour NNS cord-006870-f5w6fw6q 4917 23 of of IN cord-006870-f5w6fw6q 4917 24 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 4917 25 rupture rupture NN cord-006870-f5w6fw6q 4917 26 . . . cord-006870-f5w6fw6q 4918 1 Although although IN cord-006870-f5w6fw6q 4918 2 EBI EBI NNP cord-006870-f5w6fw6q 4918 3 is be VBZ cord-006870-f5w6fw6q 4918 4 the the DT cord-006870-f5w6fw6q 4918 5 most most RBS cord-006870-f5w6fw6q 4918 6 significant significant JJ cord-006870-f5w6fw6q 4918 7 predictor predictor NN cord-006870-f5w6fw6q 4918 8 of of IN cord-006870-f5w6fw6q 4918 9 outcomes outcome NNS cord-006870-f5w6fw6q 4918 10 after after IN cord-006870-f5w6fw6q 4918 11 aSAH asah JJ cord-006870-f5w6fw6q 4918 12 , , , cord-006870-f5w6fw6q 4918 13 its -PRON- PRP$ cord-006870-f5w6fw6q 4918 14 underlying underlie VBG cord-006870-f5w6fw6q 4918 15 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 4918 16 is be VBZ cord-006870-f5w6fw6q 4918 17 not not RB cord-006870-f5w6fw6q 4918 18 well well RB cord-006870-f5w6fw6q 4918 19 understood understand VBN cord-006870-f5w6fw6q 4918 20 . . . cord-006870-f5w6fw6q 4919 1 We -PRON- PRP cord-006870-f5w6fw6q 4919 2 hypothesize hypothesize VBP cord-006870-f5w6fw6q 4919 3 that that IN cord-006870-f5w6fw6q 4919 4 EBI EBI NNP cord-006870-f5w6fw6q 4919 5 after after IN cord-006870-f5w6fw6q 4919 6 aSAH asah NN cord-006870-f5w6fw6q 4919 7 is be VBZ cord-006870-f5w6fw6q 4919 8 associated associate VBN cord-006870-f5w6fw6q 4919 9 with with IN cord-006870-f5w6fw6q 4919 10 an an DT cord-006870-f5w6fw6q 4919 11 increase increase NN cord-006870-f5w6fw6q 4919 12 in in IN cord-006870-f5w6fw6q 4919 13 peripheral peripheral JJ cord-006870-f5w6fw6q 4919 14 inflammation inflammation NN cord-006870-f5w6fw6q 4919 15 measured measure VBN cord-006870-f5w6fw6q 4919 16 by by IN cord-006870-f5w6fw6q 4919 17 cytokine cytokine JJ cord-006870-f5w6fw6q 4919 18 expression expression NN cord-006870-f5w6fw6q 4919 19 levels level NNS cord-006870-f5w6fw6q 4919 20 and and CC cord-006870-f5w6fw6q 4919 21 changes change VBZ cord-006870-f5w6fw6q 4919 22 associations association NNS cord-006870-f5w6fw6q 4919 23 between between IN cord-006870-f5w6fw6q 4919 24 cytokines cytokine NNS cord-006870-f5w6fw6q 4919 25 . . . cord-006870-f5w6fw6q 4920 1 Methods method NNS cord-006870-f5w6fw6q 4920 2 aSAH asah VBP cord-006870-f5w6fw6q 4920 3 patients patient NNS cord-006870-f5w6fw6q 4920 4 were be VBD cord-006870-f5w6fw6q 4920 5 enrolled enrol VBN cord-006870-f5w6fw6q 4920 6 into into IN cord-006870-f5w6fw6q 4920 7 a a DT cord-006870-f5w6fw6q 4920 8 prospective prospective JJ cord-006870-f5w6fw6q 4920 9 observational observational JJ cord-006870-f5w6fw6q 4920 10 study study NN cord-006870-f5w6fw6q 4920 11 and and CC cord-006870-f5w6fw6q 4920 12 were be VBD cord-006870-f5w6fw6q 4920 13 assessed assess VBN cord-006870-f5w6fw6q 4920 14 for for IN cord-006870-f5w6fw6q 4920 15 markers marker NNS cord-006870-f5w6fw6q 4920 16 of of IN cord-006870-f5w6fw6q 4920 17 EBI EBI NNP cord-006870-f5w6fw6q 4920 18 : : : cord-006870-f5w6fw6q 4920 19 global global JJ cord-006870-f5w6fw6q 4920 20 cerebral cerebral JJ cord-006870-f5w6fw6q 4920 21 edema edema NN cord-006870-f5w6fw6q 4920 22 ( ( -LRB- cord-006870-f5w6fw6q 4920 23 GCE GCE NNP cord-006870-f5w6fw6q 4920 24 ) ) -RRB- cord-006870-f5w6fw6q 4920 25 , , , cord-006870-f5w6fw6q 4920 26 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4920 27 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4920 28 early early JJ cord-006870-f5w6fw6q 4920 29 brain brain NN cord-006870-f5w6fw6q 4920 30 edema edema NN cord-006870-f5w6fw6q 4920 31 score score NN cord-006870-f5w6fw6q 4920 32 ( ( -LRB- cord-006870-f5w6fw6q 4920 33 SEBES SEBES NNP cord-006870-f5w6fw6q 4920 34 ) ) -RRB- cord-006870-f5w6fw6q 4920 35 , , , cord-006870-f5w6fw6q 4920 36 and and CC cord-006870-f5w6fw6q 4920 37 Huntassays Huntassays NNPS cord-006870-f5w6fw6q 4920 38 to to TO cord-006870-f5w6fw6q 4920 39 determine determine VB cord-006870-f5w6fw6q 4920 40 levels level NNS cord-006870-f5w6fw6q 4920 41 of of IN cord-006870-f5w6fw6q 4920 42 13 13 CD cord-006870-f5w6fw6q 4920 43 pro pro JJ cord-006870-f5w6fw6q 4920 44 - - JJ cord-006870-f5w6fw6q 4920 45 and and CC cord-006870-f5w6fw6q 4920 46 anti anti JJ cord-006870-f5w6fw6q 4920 47 - - JJ cord-006870-f5w6fw6q 4920 48 inflammatory inflammatory JJ cord-006870-f5w6fw6q 4920 49 cytokines cytokine NNS cord-006870-f5w6fw6q 4920 50 . . . cord-006870-f5w6fw6q 4921 1 Pairwise pairwise JJ cord-006870-f5w6fw6q 4921 2 correlation correlation NN cord-006870-f5w6fw6q 4921 3 coefficients coefficient NNS cord-006870-f5w6fw6q 4921 4 between between IN cord-006870-f5w6fw6q 4921 5 cytokines cytokine NNS cord-006870-f5w6fw6q 4921 6 were be VBD cord-006870-f5w6fw6q 4921 7 represented represent VBN cord-006870-f5w6fw6q 4921 8 as as IN cord-006870-f5w6fw6q 4921 9 networks network NNS cord-006870-f5w6fw6q 4921 10 . . . cord-006870-f5w6fw6q 4922 1 Cytokines cytokine NNS cord-006870-f5w6fw6q 4922 2 levels level NNS cord-006870-f5w6fw6q 4922 3 and and CC cord-006870-f5w6fw6q 4922 4 differences difference NNS cord-006870-f5w6fw6q 4922 5 in in IN cord-006870-f5w6fw6q 4922 6 correlation correlation NN cord-006870-f5w6fw6q 4922 7 networks network NNS cord-006870-f5w6fw6q 4922 8 were be VBD cord-006870-f5w6fw6q 4922 9 compared compare VBN cord-006870-f5w6fw6q 4922 10 between between IN cord-006870-f5w6fw6q 4922 11 EBI EBI NNP cord-006870-f5w6fw6q 4922 12 groups group NNS cord-006870-f5w6fw6q 4922 13 . . . cord-006870-f5w6fw6q 4923 1 Of of IN cord-006870-f5w6fw6q 4923 2 the the DT cord-006870-f5w6fw6q 4923 3 71 71 CD cord-006870-f5w6fw6q 4923 4 patients patient NNS cord-006870-f5w6fw6q 4923 5 enrolled enrol VBN cord-006870-f5w6fw6q 4923 6 in in IN cord-006870-f5w6fw6q 4923 7 t t NN cord-006870-f5w6fw6q 4923 8 associated associate VBN cord-006870-f5w6fw6q 4923 9 with with IN cord-006870-f5w6fw6q 4923 10 high high JJ cord-006870-f5w6fw6q 4923 11 grade grade NN cord-006870-f5w6fw6q 4923 12 SEBES SEBES NNP cord-006870-f5w6fw6q 4923 13 . . . cord-006870-f5w6fw6q 4924 1 Correlation correlation NN cord-006870-f5w6fw6q 4924 2 network network NN cord-006870-f5w6fw6q 4924 3 analysis analysis NN cord-006870-f5w6fw6q 4924 4 suggests suggest VBZ cord-006870-f5w6fw6q 4924 5 higher high JJR cord-006870-f5w6fw6q 4924 6 systematic systematic JJ cord-006870-f5w6fw6q 4924 7 inflammation inflammation NN cord-006870-f5w6fw6q 4924 8 Conclusions conclusion NNS cord-006870-f5w6fw6q 4924 9 EBI EBI NNP cord-006870-f5w6fw6q 4924 10 after after IN cord-006870-f5w6fw6q 4924 11 SAH SAH NNP cord-006870-f5w6fw6q 4924 12 is be VBZ cord-006870-f5w6fw6q 4924 13 associated associate VBN cord-006870-f5w6fw6q 4924 14 with with IN cord-006870-f5w6fw6q 4924 15 increased increase VBN cord-006870-f5w6fw6q 4924 16 levels level NNS cord-006870-f5w6fw6q 4924 17 of of IN cord-006870-f5w6fw6q 4924 18 specific specific JJ cord-006870-f5w6fw6q 4924 19 cytokines cytokine NNS cord-006870-f5w6fw6q 4924 20 . . . cord-006870-f5w6fw6q 4925 1 Peripheral peripheral JJ cord-006870-f5w6fw6q 4925 2 levels level NNS cord-006870-f5w6fw6q 4925 3 of of IN cord-006870-f5w6fw6q 4925 4 IL10 IL10 NNP cord-006870-f5w6fw6q 4925 5 , , , cord-006870-f5w6fw6q 4925 6 IL6 il6 NN cord-006870-f5w6fw6q 4925 7 and and CC cord-006870-f5w6fw6q 4925 8 ession ession NN cord-006870-f5w6fw6q 4925 9 levels level NNS cord-006870-f5w6fw6q 4925 10 of of IN cord-006870-f5w6fw6q 4925 11 individual individual JJ cord-006870-f5w6fw6q 4925 12 cytokines cytokine NNS cord-006870-f5w6fw6q 4925 13 may may MD cord-006870-f5w6fw6q 4925 14 offer offer VB cord-006870-f5w6fw6q 4925 15 deeper deep JJR cord-006870-f5w6fw6q 4925 16 insight insight NN cord-006870-f5w6fw6q 4925 17 into into IN cord-006870-f5w6fw6q 4925 18 the the DT cord-006870-f5w6fw6q 4925 19 underlying underlie VBG cord-006870-f5w6fw6q 4925 20 mechanisms mechanism NNS cord-006870-f5w6fw6q 4925 21 related relate VBN cord-006870-f5w6fw6q 4925 22 to to IN cord-006870-f5w6fw6q 4925 23 EBI EBI NNP cord-006870-f5w6fw6q 4925 24 . . . cord-006870-f5w6fw6q 4926 1 Few few JJ cord-006870-f5w6fw6q 4926 2 recent recent JJ cord-006870-f5w6fw6q 4926 3 studies study NNS cord-006870-f5w6fw6q 4926 4 have have VBP cord-006870-f5w6fw6q 4926 5 evaluated evaluate VBN cord-006870-f5w6fw6q 4926 6 health health NN cord-006870-f5w6fw6q 4926 7 resource resource NN cord-006870-f5w6fw6q 4926 8 utilization utilization NN cord-006870-f5w6fw6q 4926 9 and and CC cord-006870-f5w6fw6q 4926 10 patient patient JJ cord-006870-f5w6fw6q 4926 11 outcomes outcome NNS cord-006870-f5w6fw6q 4926 12 in in IN cord-006870-f5w6fw6q 4926 13 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4926 14 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4926 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4926 16 ( ( -LRB- cord-006870-f5w6fw6q 4926 17 aSAH asah JJ cord-006870-f5w6fw6q 4926 18 ) ) -RRB- cord-006870-f5w6fw6q 4926 19 in in IN cord-006870-f5w6fw6q 4926 20 the the DT cord-006870-f5w6fw6q 4926 21 United United NNP cord-006870-f5w6fw6q 4926 22 States States NNP cord-006870-f5w6fw6q 4926 23 . . . cord-006870-f5w6fw6q 4927 1 Empirical empirical JJ cord-006870-f5w6fw6q 4927 2 evidence evidence NN cord-006870-f5w6fw6q 4927 3 implicates implicate VBZ cord-006870-f5w6fw6q 4927 4 aSAH asah JJ cord-006870-f5w6fw6q 4927 5 as as IN cord-006870-f5w6fw6q 4927 6 one one CD cord-006870-f5w6fw6q 4927 7 of of IN cord-006870-f5w6fw6q 4927 8 the the DT cord-006870-f5w6fw6q 4927 9 highest high JJS cord-006870-f5w6fw6q 4927 10 cost cost NN cord-006870-f5w6fw6q 4927 11 diseases disease NNS cord-006870-f5w6fw6q 4927 12 treated treat VBN cord-006870-f5w6fw6q 4927 13 in in IN cord-006870-f5w6fw6q 4927 14 the the DT cord-006870-f5w6fw6q 4927 15 hospital hospital NN cord-006870-f5w6fw6q 4927 16 . . . cord-006870-f5w6fw6q 4928 1 We -PRON- PRP cord-006870-f5w6fw6q 4928 2 identified identify VBD cord-006870-f5w6fw6q 4928 3 aSAH asah JJ cord-006870-f5w6fw6q 4928 4 patients patient NNS cord-006870-f5w6fw6q 4928 5 to to TO cord-006870-f5w6fw6q 4928 6 determine determine VB cord-006870-f5w6fw6q 4928 7 hospital hospital NN cord-006870-f5w6fw6q 4928 8 charge charge NN cord-006870-f5w6fw6q 4928 9 , , , cord-006870-f5w6fw6q 4928 10 length length NN cord-006870-f5w6fw6q 4928 11 of of IN cord-006870-f5w6fw6q 4928 12 stay stay NN cord-006870-f5w6fw6q 4928 13 ( ( -LRB- cord-006870-f5w6fw6q 4928 14 LOS LOS NNP cord-006870-f5w6fw6q 4928 15 ) ) -RRB- cord-006870-f5w6fw6q 4928 16 and and CC cord-006870-f5w6fw6q 4928 17 patient patient JJ cord-006870-f5w6fw6q 4928 18 disposition disposition NN cord-006870-f5w6fw6q 4928 19 associated associate VBN cord-006870-f5w6fw6q 4928 20 with with IN cord-006870-f5w6fw6q 4928 21 care care NN cord-006870-f5w6fw6q 4928 22 in in IN cord-006870-f5w6fw6q 4928 23 U.S. U.S. NNP cord-006870-f5w6fw6q 4928 24 hospitals hospital NNS cord-006870-f5w6fw6q 4928 25 using use VBG cord-006870-f5w6fw6q 4928 26 claims claim NNS cord-006870-f5w6fw6q 4928 27 data datum NNS cord-006870-f5w6fw6q 4928 28 from from IN cord-006870-f5w6fw6q 4928 29 the the DT cord-006870-f5w6fw6q 4928 30 2013 2013 CD cord-006870-f5w6fw6q 4928 31 National National NNP cord-006870-f5w6fw6q 4928 32 Inpatient Inpatient NNP cord-006870-f5w6fw6q 4928 33 Sample Sample NNP cord-006870-f5w6fw6q 4928 34 ( ( -LRB- cord-006870-f5w6fw6q 4928 35 NIS NIS NNP cord-006870-f5w6fw6q 4928 36 ) ) -RRB- cord-006870-f5w6fw6q 4928 37 . . . cord-006870-f5w6fw6q 4929 1 Patients patient NNS cord-006870-f5w6fw6q 4929 2 within within IN cord-006870-f5w6fw6q 4929 3 the the DT cord-006870-f5w6fw6q 4929 4 International International NNP cord-006870-f5w6fw6q 4929 5 Classification Classification NNP cord-006870-f5w6fw6q 4929 6 of of IN cord-006870-f5w6fw6q 4929 7 Disease Disease NNP cord-006870-f5w6fw6q 4929 8 , , , cord-006870-f5w6fw6q 4929 9 9th 9th JJ cord-006870-f5w6fw6q 4929 10 Revision revision NN cord-006870-f5w6fw6q 4929 11 ( ( -LRB- cord-006870-f5w6fw6q 4929 12 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 4929 13 ) ) -RRB- cord-006870-f5w6fw6q 4929 14 430 430 CD cord-006870-f5w6fw6q 4929 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 4929 16 code code NN cord-006870-f5w6fw6q 4929 17 were be VBD cord-006870-f5w6fw6q 4929 18 identified identify VBN cord-006870-f5w6fw6q 4929 19 ; ; : cord-006870-f5w6fw6q 4929 20 a a DT cord-006870-f5w6fw6q 4929 21 secondary secondary JJ cord-006870-f5w6fw6q 4929 22 analysis analysis NN cord-006870-f5w6fw6q 4929 23 of of IN cord-006870-f5w6fw6q 4929 24 the the DT cord-006870-f5w6fw6q 4929 25 NIS NIS NNP cord-006870-f5w6fw6q 4929 26 ( ( -LRB- cord-006870-f5w6fw6q 4929 27 2013 2013 CD cord-006870-f5w6fw6q 4929 28 ) ) -RRB- cord-006870-f5w6fw6q 4929 29 was be VBD cord-006870-f5w6fw6q 4929 30 conducted conduct VBN cord-006870-f5w6fw6q 4929 31 utilizing utilize VBG cord-006870-f5w6fw6q 4929 32 ICD-9 ICD-9 NNP cord-006870-f5w6fw6q 4929 33 Clinical Clinical NNP cord-006870-f5w6fw6q 4929 34 Modification Modification NNP cord-006870-f5w6fw6q 4929 35 codes code NNS cord-006870-f5w6fw6q 4929 36 excluding exclude VBG cord-006870-f5w6fw6q 4929 37 patients patient NNS cord-006870-f5w6fw6q 4929 38 with with IN cord-006870-f5w6fw6q 4929 39 traumatic traumatic JJ cord-006870-f5w6fw6q 4929 40 and and CC cord-006870-f5w6fw6q 4929 41 non non JJ cord-006870-f5w6fw6q 4929 42 - - JJ cord-006870-f5w6fw6q 4929 43 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 4929 44 SAH SAH NNP cord-006870-f5w6fw6q 4929 45 . . . cord-006870-f5w6fw6q 4930 1 Population population NN cord-006870-f5w6fw6q 4930 2 size size NN cord-006870-f5w6fw6q 4930 3 , , , cord-006870-f5w6fw6q 4930 4 patient patient JJ cord-006870-f5w6fw6q 4930 5 outcome outcome NN cord-006870-f5w6fw6q 4930 6 , , , cord-006870-f5w6fw6q 4930 7 average average JJ cord-006870-f5w6fw6q 4930 8 charge charge NN cord-006870-f5w6fw6q 4930 9 and and CC cord-006870-f5w6fw6q 4930 10 average average JJ cord-006870-f5w6fw6q 4930 11 LOS LOS NNP cord-006870-f5w6fw6q 4930 12 were be VBD cord-006870-f5w6fw6q 4930 13 calculated calculate VBN cord-006870-f5w6fw6q 4930 14 using use VBG cord-006870-f5w6fw6q 4930 15 subgroups subgroup NNS cord-006870-f5w6fw6q 4930 16 including include VBG cord-006870-f5w6fw6q 4930 17 : : : cord-006870-f5w6fw6q 4930 18 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 4930 19 clipping clipping NN cord-006870-f5w6fw6q 4930 20 or or CC cord-006870-f5w6fw6q 4930 21 endovascular endovascular JJ cord-006870-f5w6fw6q 4930 22 coiling coiling NN cord-006870-f5w6fw6q 4930 23 ( ( -LRB- cord-006870-f5w6fw6q 4930 24 n=5,925 n=5,925 NNP cord-006870-f5w6fw6q 4930 25 ) ) -RRB- cord-006870-f5w6fw6q 4930 26 , , , cord-006870-f5w6fw6q 4930 27 aneurysmal aneurysmal NN cord-006870-f5w6fw6q 4930 28 clipping clip VBG cord-006870-f5w6fw6q 4930 29 or or CC cord-006870-f5w6fw6q 4930 30 coiling coil VBG cord-006870-f5w6fw6q 4930 31 with with IN cord-006870-f5w6fw6q 4930 32 external external JJ cord-006870-f5w6fw6q 4930 33 ventricular ventricular JJ cord-006870-f5w6fw6q 4930 34 drain drain NN cord-006870-f5w6fw6q 4930 35 ( ( -LRB- cord-006870-f5w6fw6q 4930 36 EVD EVD NNP cord-006870-f5w6fw6q 4930 37 ) ) -RRB- cord-006870-f5w6fw6q 4930 38 ( ( -LRB- cord-006870-f5w6fw6q 4930 39 n=4,660 n=4,660 NNP cord-006870-f5w6fw6q 4930 40 ) ) -RRB- cord-006870-f5w6fw6q 4930 41 , , , cord-006870-f5w6fw6q 4930 42 use use NN cord-006870-f5w6fw6q 4930 43 of of IN cord-006870-f5w6fw6q 4930 44 EVD EVD NNP cord-006870-f5w6fw6q 4930 45 only only RB cord-006870-f5w6fw6q 4930 46 ( ( -LRB- cord-006870-f5w6fw6q 4930 47 n=2,355 n=2,355 NNP cord-006870-f5w6fw6q 4930 48 ) ) -RRB- cord-006870-f5w6fw6q 4930 49 , , , cord-006870-f5w6fw6q 4930 50 other other JJ cord-006870-f5w6fw6q 4930 51 surgical surgical JJ cord-006870-f5w6fw6q 4930 52 procedures procedure NNS cord-006870-f5w6fw6q 4930 53 ( ( -LRB- cord-006870-f5w6fw6q 4930 54 n=880 n=880 CD cord-006870-f5w6fw6q 4930 55 ) ) -RRB- cord-006870-f5w6fw6q 4930 56 and and CC cord-006870-f5w6fw6q 4930 57 medically medically RB cord-006870-f5w6fw6q 4930 58 managed manage VBN cord-006870-f5w6fw6q 4930 59 ( ( -LRB- cord-006870-f5w6fw6q 4930 60 n=1,545 n=1,545 NNP cord-006870-f5w6fw6q 4930 61 ) ) -RRB- cord-006870-f5w6fw6q 4930 62 . . . cord-006870-f5w6fw6q 4931 1 Analyses analysis NNS cord-006870-f5w6fw6q 4931 2 were be VBD cord-006870-f5w6fw6q 4931 3 survey survey NN cord-006870-f5w6fw6q 4931 4 - - HYPH cord-006870-f5w6fw6q 4931 5 weighted weight VBN cord-006870-f5w6fw6q 4931 6 and and CC cord-006870-f5w6fw6q 4931 7 adjusted adjust VBN cord-006870-f5w6fw6q 4931 8 for for IN cord-006870-f5w6fw6q 4931 9 patient patient NN cord-006870-f5w6fw6q 4931 10 and and CC cord-006870-f5w6fw6q 4931 11 hospital hospital NN cord-006870-f5w6fw6q 4931 12 characteristics characteristic NNS cord-006870-f5w6fw6q 4931 13 . . . cord-006870-f5w6fw6q 4932 1 In in IN cord-006870-f5w6fw6q 4932 2 2013 2013 CD cord-006870-f5w6fw6q 4932 3 , , , cord-006870-f5w6fw6q 4932 4 aSAH aSAH NNP cord-006870-f5w6fw6q 4932 5 resulted result VBN cord-006870-f5w6fw6q 4932 6 in in IN cord-006870-f5w6fw6q 4932 7 an an DT cord-006870-f5w6fw6q 4932 8 average average NN cord-006870-f5w6fw6q 4932 9 per per IN cord-006870-f5w6fw6q 4932 10 patient patient JJ cord-006870-f5w6fw6q 4932 11 hospital hospital NN cord-006870-f5w6fw6q 4932 12 charge charge NN cord-006870-f5w6fw6q 4932 13 of of IN cord-006870-f5w6fw6q 4932 14 $ $ $ cord-006870-f5w6fw6q 4932 15 308,139 308,139 CD cord-006870-f5w6fw6q 4932 16 , , , cord-006870-f5w6fw6q 4932 17 an an DT cord-006870-f5w6fw6q 4932 18 average average JJ cord-006870-f5w6fw6q 4932 19 LOS LOS NNP cord-006870-f5w6fw6q 4932 20 of of IN cord-006870-f5w6fw6q 4932 21 17 17 CD cord-006870-f5w6fw6q 4932 22 days day NNS cord-006870-f5w6fw6q 4932 23 , , , cord-006870-f5w6fw6q 4932 24 an an DT cord-006870-f5w6fw6q 4932 25 average average JJ cord-006870-f5w6fw6q 4932 26 mortality mortality NN cord-006870-f5w6fw6q 4932 27 of of IN cord-006870-f5w6fw6q 4932 28 20 20 CD cord-006870-f5w6fw6q 4932 29 % % NN cord-006870-f5w6fw6q 4932 30 and and CC cord-006870-f5w6fw6q 4932 31 total total JJ cord-006870-f5w6fw6q 4932 32 , , , cord-006870-f5w6fw6q 4932 33 annual annual JJ cord-006870-f5w6fw6q 4932 34 hospital hospital NN cord-006870-f5w6fw6q 4932 35 charges charge NNS cord-006870-f5w6fw6q 4932 36 of of IN cord-006870-f5w6fw6q 4932 37 $ $ $ cord-006870-f5w6fw6q 4932 38 4.7 4.7 CD cord-006870-f5w6fw6q 4932 39 billion billion CD cord-006870-f5w6fw6q 4932 40 . . . cord-006870-f5w6fw6q 4933 1 The the DT cord-006870-f5w6fw6q 4933 2 highest high JJS cord-006870-f5w6fw6q 4933 3 average average JJ cord-006870-f5w6fw6q 4933 4 charge charge NN cord-006870-f5w6fw6q 4933 5 per per IN cord-006870-f5w6fw6q 4933 6 patient patient NN cord-006870-f5w6fw6q 4933 7 ( ( -LRB- cord-006870-f5w6fw6q 4933 8 $ $ $ cord-006870-f5w6fw6q 4933 9 417,042 417,042 CD cord-006870-f5w6fw6q 4933 10 ) ) -RRB- cord-006870-f5w6fw6q 4933 11 and and CC cord-006870-f5w6fw6q 4933 12 hospital hospital NN cord-006870-f5w6fw6q 4933 13 LOS LOS NNP cord-006870-f5w6fw6q 4933 14 ( ( -LRB- cord-006870-f5w6fw6q 4933 15 22 22 CD cord-006870-f5w6fw6q 4933 16 days day NNS cord-006870-f5w6fw6q 4933 17 ) ) -RRB- cord-006870-f5w6fw6q 4933 18 were be VBD cord-006870-f5w6fw6q 4933 19 attributed attribute VBN cord-006870-f5w6fw6q 4933 20 to to IN cord-006870-f5w6fw6q 4933 21 clipped clipped JJ cord-006870-f5w6fw6q 4933 22 or or CC cord-006870-f5w6fw6q 4933 23 coiled coiled JJ cord-006870-f5w6fw6q 4933 24 patients patient NNS cord-006870-f5w6fw6q 4933 25 with with IN cord-006870-f5w6fw6q 4933 26 EVD EVD NNP cord-006870-f5w6fw6q 4933 27 , , , cord-006870-f5w6fw6q 4933 28 and and CC cord-006870-f5w6fw6q 4933 29 highest high JJS cord-006870-f5w6fw6q 4933 30 mortality mortality NN cord-006870-f5w6fw6q 4933 31 ( ( -LRB- cord-006870-f5w6fw6q 4933 32 47 47 CD cord-006870-f5w6fw6q 4933 33 % % NN cord-006870-f5w6fw6q 4933 34 ) ) -RRB- cord-006870-f5w6fw6q 4933 35 found find VBN cord-006870-f5w6fw6q 4933 36 in in IN cord-006870-f5w6fw6q 4933 37 medically medically RB cord-006870-f5w6fw6q 4933 38 managed manage VBN cord-006870-f5w6fw6q 4933 39 patients patient NNS cord-006870-f5w6fw6q 4933 40 . . . cord-006870-f5w6fw6q 4934 1 These these DT cord-006870-f5w6fw6q 4934 2 data datum NNS cord-006870-f5w6fw6q 4934 3 support support VBP cord-006870-f5w6fw6q 4934 4 the the DT cord-006870-f5w6fw6q 4934 5 conclusion conclusion NN cord-006870-f5w6fw6q 4934 6 that that IN cord-006870-f5w6fw6q 4934 7 aSAH aSAH NNP cord-006870-f5w6fw6q 4934 8 is be VBZ cord-006870-f5w6fw6q 4934 9 a a DT cord-006870-f5w6fw6q 4934 10 high high JJ cord-006870-f5w6fw6q 4934 11 cost cost NN cord-006870-f5w6fw6q 4934 12 illness illness NN cord-006870-f5w6fw6q 4934 13 managed manage VBN cord-006870-f5w6fw6q 4934 14 in in IN cord-006870-f5w6fw6q 4934 15 U.S. U.S. NNP cord-006870-f5w6fw6q 4934 16 hospitals hospital NNS cord-006870-f5w6fw6q 4934 17 , , , cord-006870-f5w6fw6q 4934 18 and and CC cord-006870-f5w6fw6q 4934 19 help help VB cord-006870-f5w6fw6q 4934 20 raise raise VB cord-006870-f5w6fw6q 4934 21 awareness awareness NN cord-006870-f5w6fw6q 4934 22 to to IN cord-006870-f5w6fw6q 4934 23 the the DT cord-006870-f5w6fw6q 4934 24 potential potential JJ cord-006870-f5w6fw6q 4934 25 economic economic JJ cord-006870-f5w6fw6q 4934 26 benefits benefit NNS cord-006870-f5w6fw6q 4934 27 resulting result VBG cord-006870-f5w6fw6q 4934 28 from from IN cord-006870-f5w6fw6q 4934 29 developing develop VBG cord-006870-f5w6fw6q 4934 30 safer safe JJR cord-006870-f5w6fw6q 4934 31 , , , cord-006870-f5w6fw6q 4934 32 more more RBR cord-006870-f5w6fw6q 4934 33 effective effective JJ cord-006870-f5w6fw6q 4934 34 therapies therapy NNS cord-006870-f5w6fw6q 4934 35 . . . cord-006870-f5w6fw6q 4935 1 Additional additional JJ cord-006870-f5w6fw6q 4935 2 analyses analysis NNS cord-006870-f5w6fw6q 4935 3 with with IN cord-006870-f5w6fw6q 4935 4 updated update VBN cord-006870-f5w6fw6q 4935 5 datasets dataset NNS cord-006870-f5w6fw6q 4935 6 including include VBG cord-006870-f5w6fw6q 4935 7 lifetime lifetime NN cord-006870-f5w6fw6q 4935 8 burden burden NN cord-006870-f5w6fw6q 4935 9 of of IN cord-006870-f5w6fw6q 4935 10 aSAH asah JJ cord-006870-f5w6fw6q 4935 11 ( ( -LRB- cord-006870-f5w6fw6q 4935 12 e.g. e.g. IN cord-006870-f5w6fw6q 4935 13 physician physician NN cord-006870-f5w6fw6q 4935 14 fees fee NNS cord-006870-f5w6fw6q 4935 15 , , , cord-006870-f5w6fw6q 4935 16 long long JJ cord-006870-f5w6fw6q 4935 17 term term NN cord-006870-f5w6fw6q 4935 18 medical medical JJ cord-006870-f5w6fw6q 4935 19 and and CC cord-006870-f5w6fw6q 4935 20 care care NN cord-006870-f5w6fw6q 4935 21 costs cost NNS cord-006870-f5w6fw6q 4935 22 , , , cord-006870-f5w6fw6q 4935 23 hospital hospital NN cord-006870-f5w6fw6q 4935 24 re re NN cord-006870-f5w6fw6q 4935 25 - - NN cord-006870-f5w6fw6q 4935 26 admission admission NN cord-006870-f5w6fw6q 4935 27 impact impact NN cord-006870-f5w6fw6q 4935 28 , , , cord-006870-f5w6fw6q 4935 29 quality quality NN cord-006870-f5w6fw6q 4935 30 of of IN cord-006870-f5w6fw6q 4935 31 life life NN cord-006870-f5w6fw6q 4935 32 , , , cord-006870-f5w6fw6q 4935 33 productivity productivity NN cord-006870-f5w6fw6q 4935 34 loss loss NN cord-006870-f5w6fw6q 4935 35 , , , cord-006870-f5w6fw6q 4935 36 caregiver caregiver NN cord-006870-f5w6fw6q 4935 37 burden burden NN cord-006870-f5w6fw6q 4935 38 ) ) -RRB- cord-006870-f5w6fw6q 4935 39 should should MD cord-006870-f5w6fw6q 4935 40 be be VB cord-006870-f5w6fw6q 4935 41 explored explore VBN cord-006870-f5w6fw6q 4935 42 to to TO cord-006870-f5w6fw6q 4935 43 understand understand VB cord-006870-f5w6fw6q 4935 44 the the DT cord-006870-f5w6fw6q 4935 45 full full JJ cord-006870-f5w6fw6q 4935 46 economic economic JJ cord-006870-f5w6fw6q 4935 47 burden burden NN cord-006870-f5w6fw6q 4935 48 of of IN cord-006870-f5w6fw6q 4935 49 aSAH asah JJ cord-006870-f5w6fw6q 4935 50 and and CC cord-006870-f5w6fw6q 4935 51 the the DT cord-006870-f5w6fw6q 4935 52 potential potential JJ cord-006870-f5w6fw6q 4935 53 cost cost NN cord-006870-f5w6fw6q 4935 54 effectiveness effectiveness NN cord-006870-f5w6fw6q 4935 55 of of IN cord-006870-f5w6fw6q 4935 56 new new JJ cord-006870-f5w6fw6q 4935 57 therapies therapy NNS cord-006870-f5w6fw6q 4935 58 . . . cord-006870-f5w6fw6q 4936 1 External external JJ cord-006870-f5w6fw6q 4936 2 ventricular ventricular JJ cord-006870-f5w6fw6q 4936 3 drain drain NN cord-006870-f5w6fw6q 4936 4 ( ( -LRB- cord-006870-f5w6fw6q 4936 5 EVD EVD NNP cord-006870-f5w6fw6q 4936 6 ) ) -RRB- cord-006870-f5w6fw6q 4936 7 placement placement NN cord-006870-f5w6fw6q 4936 8 is be VBZ cord-006870-f5w6fw6q 4936 9 a a DT cord-006870-f5w6fw6q 4936 10 mainstay mainstay NN cord-006870-f5w6fw6q 4936 11 of of IN cord-006870-f5w6fw6q 4936 12 treatment treatment NN cord-006870-f5w6fw6q 4936 13 for for IN cord-006870-f5w6fw6q 4936 14 patients patient NNS cord-006870-f5w6fw6q 4936 15 with with IN cord-006870-f5w6fw6q 4936 16 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 4936 17 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4936 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4936 19 with with IN cord-006870-f5w6fw6q 4936 20 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 4936 21 or or CC cord-006870-f5w6fw6q 4936 22 elevated elevate VBN cord-006870-f5w6fw6q 4936 23 intracranial intracranial JJ cord-006870-f5w6fw6q 4936 24 pressures pressure NNS cord-006870-f5w6fw6q 4936 25 , , , cord-006870-f5w6fw6q 4936 26 but but CC cord-006870-f5w6fw6q 4936 27 the the DT cord-006870-f5w6fw6q 4936 28 optimal optimal JJ cord-006870-f5w6fw6q 4936 29 strategy strategy NN cord-006870-f5w6fw6q 4936 30 for for IN cord-006870-f5w6fw6q 4936 31 EVD EVD NNP cord-006870-f5w6fw6q 4936 32 management management NN cord-006870-f5w6fw6q 4936 33 is be VBZ cord-006870-f5w6fw6q 4936 34 still still RB cord-006870-f5w6fw6q 4936 35 unclear unclear JJ cord-006870-f5w6fw6q 4936 36 . . . cord-006870-f5w6fw6q 4937 1 The the DT cord-006870-f5w6fw6q 4937 2 goal goal NN cord-006870-f5w6fw6q 4937 3 of of IN cord-006870-f5w6fw6q 4937 4 this this DT cord-006870-f5w6fw6q 4937 5 study study NN cord-006870-f5w6fw6q 4937 6 was be VBD cord-006870-f5w6fw6q 4937 7 to to TO cord-006870-f5w6fw6q 4937 8 compare compare VB cord-006870-f5w6fw6q 4937 9 the the DT cord-006870-f5w6fw6q 4937 10 impact impact NN cord-006870-f5w6fw6q 4937 11 of of IN cord-006870-f5w6fw6q 4937 12 EVD EVD NNP cord-006870-f5w6fw6q 4937 13 clamping clamping NN cord-006870-f5w6fw6q 4937 14 at at IN cord-006870-f5w6fw6q 4937 15 three three CD cord-006870-f5w6fw6q 4937 16 different different JJ cord-006870-f5w6fw6q 4937 17 levels level NNS cord-006870-f5w6fw6q 4937 18 on on IN cord-006870-f5w6fw6q 4937 19 the the DT cord-006870-f5w6fw6q 4937 20 duration duration NN cord-006870-f5w6fw6q 4937 21 of of IN cord-006870-f5w6fw6q 4937 22 drain drain NN cord-006870-f5w6fw6q 4937 23 placement placement NN cord-006870-f5w6fw6q 4937 24 and and CC cord-006870-f5w6fw6q 4937 25 the the DT cord-006870-f5w6fw6q 4937 26 intensive intensive JJ cord-006870-f5w6fw6q 4937 27 care care NN cord-006870-f5w6fw6q 4937 28 unit unit NN cord-006870-f5w6fw6q 4937 29 ( ( -LRB- cord-006870-f5w6fw6q 4937 30 ICU ICU NNP cord-006870-f5w6fw6q 4937 31 ) ) -RRB- cord-006870-f5w6fw6q 4937 32 length length NN cord-006870-f5w6fw6q 4937 33 of of IN cord-006870-f5w6fw6q 4937 34 stay stay NN cord-006870-f5w6fw6q 4937 35 . . . cord-006870-f5w6fw6q 4938 1 We -PRON- PRP cord-006870-f5w6fw6q 4938 2 performed perform VBD cord-006870-f5w6fw6q 4938 3 a a DT cord-006870-f5w6fw6q 4938 4 retrospective retrospective JJ cord-006870-f5w6fw6q 4938 5 analysis analysis NN cord-006870-f5w6fw6q 4938 6 of of IN cord-006870-f5w6fw6q 4938 7 patients patient NNS cord-006870-f5w6fw6q 4938 8 admitted admit VBN cord-006870-f5w6fw6q 4938 9 with with IN cord-006870-f5w6fw6q 4938 10 aneurysmal aneurysmal NN cord-006870-f5w6fw6q 4938 11 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4938 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4938 13 to to IN cord-006870-f5w6fw6q 4938 14 the the DT cord-006870-f5w6fw6q 4938 15 neurological neurological JJ cord-006870-f5w6fw6q 4938 16 ICU ICU NNP cord-006870-f5w6fw6q 4938 17 from from IN cord-006870-f5w6fw6q 4938 18 December December NNP cord-006870-f5w6fw6q 4938 19 2015 2015 CD cord-006870-f5w6fw6q 4938 20 to to IN cord-006870-f5w6fw6q 4938 21 January January NNP cord-006870-f5w6fw6q 4938 22 2017 2017 CD cord-006870-f5w6fw6q 4938 23 and and CC cord-006870-f5w6fw6q 4938 24 included include VBD cord-006870-f5w6fw6q 4938 25 all all DT cord-006870-f5w6fw6q 4938 26 patients patient NNS cord-006870-f5w6fw6q 4938 27 who who WP cord-006870-f5w6fw6q 4938 28 had have VBD cord-006870-f5w6fw6q 4938 29 an an DT cord-006870-f5w6fw6q 4938 30 EVD EVD NNP cord-006870-f5w6fw6q 4938 31 placed place VBN cord-006870-f5w6fw6q 4938 32 . . . cord-006870-f5w6fw6q 4939 1 Patients patient NNS cord-006870-f5w6fw6q 4939 2 who who WP cord-006870-f5w6fw6q 4939 3 died die VBD cord-006870-f5w6fw6q 4939 4 were be VBD cord-006870-f5w6fw6q 4939 5 excluded exclude VBN cord-006870-f5w6fw6q 4939 6 from from IN cord-006870-f5w6fw6q 4939 7 the the DT cord-006870-f5w6fw6q 4939 8 study study NN cord-006870-f5w6fw6q 4939 9 . . . cord-006870-f5w6fw6q 4940 1 Patients patient NNS cord-006870-f5w6fw6q 4940 2 were be VBD cord-006870-f5w6fw6q 4940 3 divided divide VBN cord-006870-f5w6fw6q 4940 4 into into IN cord-006870-f5w6fw6q 4940 5 three three CD cord-006870-f5w6fw6q 4940 6 groups group NNS cord-006870-f5w6fw6q 4940 7 : : : cord-006870-f5w6fw6q 4940 8 patients patient NNS cord-006870-f5w6fw6q 4940 9 whose whose WP$ cord-006870-f5w6fw6q 4940 10 EVD EVD NNP cord-006870-f5w6fw6q 4940 11 was be VBD cord-006870-f5w6fw6q 4940 12 clamped clamp VBN cord-006870-f5w6fw6q 4940 13 at at IN cord-006870-f5w6fw6q 4940 14 10 10 CD cord-006870-f5w6fw6q 4940 15 mmHg mmHg NNS cord-006870-f5w6fw6q 4940 16 , , , cord-006870-f5w6fw6q 4940 17 patients patient NNS cord-006870-f5w6fw6q 4940 18 whose whose WP$ cord-006870-f5w6fw6q 4940 19 EVD EVD NNP cord-006870-f5w6fw6q 4940 20 was be VBD cord-006870-f5w6fw6q 4940 21 clamped clamp VBN cord-006870-f5w6fw6q 4940 22 at at IN cord-006870-f5w6fw6q 4940 23 15 15 CD cord-006870-f5w6fw6q 4940 24 mmHg mmHg NNS cord-006870-f5w6fw6q 4940 25 , , , cord-006870-f5w6fw6q 4940 26 and and CC cord-006870-f5w6fw6q 4940 27 patients patient NNS cord-006870-f5w6fw6q 4940 28 whose whose WP$ cord-006870-f5w6fw6q 4940 29 EVD EVD NNP cord-006870-f5w6fw6q 4940 30 was be VBD cord-006870-f5w6fw6q 4940 31 clamped clamp VBN cord-006870-f5w6fw6q 4940 32 at at IN cord-006870-f5w6fw6q 4941 1 20 20 CD cord-006870-f5w6fw6q 4941 2 mmHg mmHg NNS cord-006870-f5w6fw6q 4941 3 . . . cord-006870-f5w6fw6q 4941 4 Duration duration NN cord-006870-f5w6fw6q 4941 5 of of IN cord-006870-f5w6fw6q 4941 6 drain drain NN cord-006870-f5w6fw6q 4941 7 placement placement NN cord-006870-f5w6fw6q 4941 8 in in IN cord-006870-f5w6fw6q 4941 9 days day NNS cord-006870-f5w6fw6q 4941 10 and and CC cord-006870-f5w6fw6q 4941 11 ICU ICU NNP cord-006870-f5w6fw6q 4941 12 length length NN cord-006870-f5w6fw6q 4941 13 of of IN cord-006870-f5w6fw6q 4941 14 stay stay NN cord-006870-f5w6fw6q 4941 15 in in IN cord-006870-f5w6fw6q 4941 16 days day NNS cord-006870-f5w6fw6q 4941 17 was be VBD cord-006870-f5w6fw6q 4941 18 compared compare VBN cord-006870-f5w6fw6q 4941 19 among among IN cord-006870-f5w6fw6q 4941 20 the the DT cord-006870-f5w6fw6q 4941 21 3 3 CD cord-006870-f5w6fw6q 4941 22 groups group NNS cord-006870-f5w6fw6q 4941 23 using use VBG cord-006870-f5w6fw6q 4941 24 an an DT cord-006870-f5w6fw6q 4941 25 analysis analysis NN cord-006870-f5w6fw6q 4941 26 of of IN cord-006870-f5w6fw6q 4941 27 variance variance NN cord-006870-f5w6fw6q 4941 28 ( ( -LRB- cord-006870-f5w6fw6q 4941 29 ANOVA ANOVA NNP cord-006870-f5w6fw6q 4941 30 ) ) -RRB- cord-006870-f5w6fw6q 4941 31 . . . cord-006870-f5w6fw6q 4942 1 Outcomes outcome NNS cord-006870-f5w6fw6q 4942 2 were be VBD cord-006870-f5w6fw6q 4942 3 adjusted adjust VBN cord-006870-f5w6fw6q 4942 4 for for IN cord-006870-f5w6fw6q 4942 5 presenting present VBG cord-006870-f5w6fw6q 4942 6 Hunt Hunt NNP cord-006870-f5w6fw6q 4942 7 - - HYPH cord-006870-f5w6fw6q 4942 8 Hess Hess NNP cord-006870-f5w6fw6q 4942 9 score score NN cord-006870-f5w6fw6q 4942 10 , , , cord-006870-f5w6fw6q 4942 11 modified modify VBD cord-006870-f5w6fw6q 4942 12 Fisher Fisher NNP cord-006870-f5w6fw6q 4942 13 grade grade NN cord-006870-f5w6fw6q 4942 14 , , , cord-006870-f5w6fw6q 4942 15 gender gender NN cord-006870-f5w6fw6q 4942 16 , , , cord-006870-f5w6fw6q 4942 17 and and CC cord-006870-f5w6fw6q 4942 18 age age NN cord-006870-f5w6fw6q 4942 19 . . . cord-006870-f5w6fw6q 4943 1 There there EX cord-006870-f5w6fw6q 4943 2 were be VBD cord-006870-f5w6fw6q 4943 3 10 10 CD cord-006870-f5w6fw6q 4943 4 patients patient NNS cord-006870-f5w6fw6q 4943 5 who who WP cord-006870-f5w6fw6q 4943 6 had have VBD cord-006870-f5w6fw6q 4943 7 their -PRON- PRP$ cord-006870-f5w6fw6q 4943 8 EVD EVD NNP cord-006870-f5w6fw6q 4943 9 clamped clamp VBN cord-006870-f5w6fw6q 4943 10 at at IN cord-006870-f5w6fw6q 4943 11 10 10 CD cord-006870-f5w6fw6q 4943 12 mmHg mmHg NNS cord-006870-f5w6fw6q 4943 13 , , , cord-006870-f5w6fw6q 4943 14 23 23 CD cord-006870-f5w6fw6q 4943 15 who who WP cord-006870-f5w6fw6q 4943 16 had have VBD cord-006870-f5w6fw6q 4943 17 their -PRON- PRP$ cord-006870-f5w6fw6q 4943 18 EVD EVD NNP cord-006870-f5w6fw6q 4943 19 clamped clamp VBN cord-006870-f5w6fw6q 4943 20 at at IN cord-006870-f5w6fw6q 4943 21 15 15 CD cord-006870-f5w6fw6q 4943 22 mmHg mmHg NNS cord-006870-f5w6fw6q 4943 23 , , , cord-006870-f5w6fw6q 4943 24 and and CC cord-006870-f5w6fw6q 4943 25 25 25 CD cord-006870-f5w6fw6q 4943 26 who who WP cord-006870-f5w6fw6q 4943 27 had have VBD cord-006870-f5w6fw6q 4943 28 their -PRON- PRP$ cord-006870-f5w6fw6q 4943 29 EVD EVD NNP cord-006870-f5w6fw6q 4943 30 clamped clamp VBN cord-006870-f5w6fw6q 4943 31 at at IN cord-006870-f5w6fw6q 4943 32 20 20 CD cord-006870-f5w6fw6q 4943 33 mmHg mmHg NNS cord-006870-f5w6fw6q 4943 34 . . . cord-006870-f5w6fw6q 4944 1 There there EX cord-006870-f5w6fw6q 4944 2 was be VBD cord-006870-f5w6fw6q 4944 3 no no DT cord-006870-f5w6fw6q 4944 4 difference difference NN cord-006870-f5w6fw6q 4944 5 in in IN cord-006870-f5w6fw6q 4944 6 duration duration NN cord-006870-f5w6fw6q 4944 7 of of IN cord-006870-f5w6fw6q 4944 8 EVD EVD NNP cord-006870-f5w6fw6q 4944 9 placement placement NN cord-006870-f5w6fw6q 4944 10 among among IN cord-006870-f5w6fw6q 4944 11 the the DT cord-006870-f5w6fw6q 4944 12 three three CD cord-006870-f5w6fw6q 4944 13 groups group NNS cord-006870-f5w6fw6q 4944 14 ( ( -LRB- cord-006870-f5w6fw6q 4944 15 adjusted adjust VBN cord-006870-f5w6fw6q 4944 16 p p NN cord-006870-f5w6fw6q 4944 17 - - HYPH cord-006870-f5w6fw6q 4944 18 value value NN cord-006870-f5w6fw6q 4944 19 0.36 0.36 CD cord-006870-f5w6fw6q 4944 20 , , , cord-006870-f5w6fw6q 4944 21 unadjusted unadjusted JJ cord-006870-f5w6fw6q 4944 22 p p NN cord-006870-f5w6fw6q 4944 23 - - HYPH cord-006870-f5w6fw6q 4944 24 value value NN cord-006870-f5w6fw6q 4944 25 0.6 0.6 CD cord-006870-f5w6fw6q 4944 26 ) ) -RRB- cord-006870-f5w6fw6q 4944 27 nor nor CC cord-006870-f5w6fw6q 4944 28 in in IN cord-006870-f5w6fw6q 4944 29 ICU ICU NNP cord-006870-f5w6fw6q 4944 30 length length NN cord-006870-f5w6fw6q 4944 31 of of IN cord-006870-f5w6fw6q 4944 32 stay stay NN cord-006870-f5w6fw6q 4944 33 ( ( -LRB- cord-006870-f5w6fw6q 4944 34 adjusted adjust VBN cord-006870-f5w6fw6q 4944 35 p p NN cord-006870-f5w6fw6q 4944 36 - - HYPH cord-006870-f5w6fw6q 4944 37 value value NN cord-006870-f5w6fw6q 4944 38 0.18 0.18 CD cord-006870-f5w6fw6q 4944 39 , , , cord-006870-f5w6fw6q 4944 40 unadjusted unadjusted JJ cord-006870-f5w6fw6q 4944 41 p p NN cord-006870-f5w6fw6q 4944 42 - - HYPH cord-006870-f5w6fw6q 4944 43 value value NN cord-006870-f5w6fw6q 4944 44 0.43 0.43 CD cord-006870-f5w6fw6q 4944 45 ) ) -RRB- cord-006870-f5w6fw6q 4944 46 . . . cord-006870-f5w6fw6q 4945 1 EVD EVD NNP cord-006870-f5w6fw6q 4945 2 clamping clamping NN cord-006870-f5w6fw6q 4945 3 at at IN cord-006870-f5w6fw6q 4945 4 three three CD cord-006870-f5w6fw6q 4945 5 different different JJ cord-006870-f5w6fw6q 4945 6 levels level NNS cord-006870-f5w6fw6q 4945 7 did do VBD cord-006870-f5w6fw6q 4945 8 not not RB cord-006870-f5w6fw6q 4945 9 affect affect VB cord-006870-f5w6fw6q 4945 10 drain drain NN cord-006870-f5w6fw6q 4945 11 duration duration NN cord-006870-f5w6fw6q 4945 12 nor nor CC cord-006870-f5w6fw6q 4945 13 length length NN cord-006870-f5w6fw6q 4945 14 of of IN cord-006870-f5w6fw6q 4945 15 stay stay NN cord-006870-f5w6fw6q 4945 16 in in IN cord-006870-f5w6fw6q 4945 17 ICU ICU NNP cord-006870-f5w6fw6q 4945 18 . . . cord-006870-f5w6fw6q 4946 1 This this DT cord-006870-f5w6fw6q 4946 2 study study NN cord-006870-f5w6fw6q 4946 3 was be VBD cord-006870-f5w6fw6q 4946 4 limited limit VBN cord-006870-f5w6fw6q 4946 5 by by IN cord-006870-f5w6fw6q 4946 6 the the DT cord-006870-f5w6fw6q 4946 7 small small JJ cord-006870-f5w6fw6q 4946 8 number number NN cord-006870-f5w6fw6q 4946 9 of of IN cord-006870-f5w6fw6q 4946 10 patients patient NNS cord-006870-f5w6fw6q 4946 11 enrolled enrol VBN cord-006870-f5w6fw6q 4946 12 . . . cord-006870-f5w6fw6q 4947 1 Further further JJ cord-006870-f5w6fw6q 4947 2 studies study NNS cord-006870-f5w6fw6q 4947 3 are be VBP cord-006870-f5w6fw6q 4947 4 need nee VBN cord-006870-f5w6fw6q 4947 5 to to TO cord-006870-f5w6fw6q 4947 6 clarify clarify VB cord-006870-f5w6fw6q 4947 7 optimal optimal JJ cord-006870-f5w6fw6q 4947 8 strategies strategy NNS cord-006870-f5w6fw6q 4947 9 for for IN cord-006870-f5w6fw6q 4947 10 EVD EVD NNP cord-006870-f5w6fw6q 4947 11 management management NN cord-006870-f5w6fw6q 4947 12 in in IN cord-006870-f5w6fw6q 4947 13 the the DT cord-006870-f5w6fw6q 4947 14 ICU ICU NNP cord-006870-f5w6fw6q 4947 15 . . . cord-006870-f5w6fw6q 4948 1 Headache headache NN cord-006870-f5w6fw6q 4948 2 is be VBZ cord-006870-f5w6fw6q 4948 3 a a DT cord-006870-f5w6fw6q 4948 4 presenting present VBG cord-006870-f5w6fw6q 4948 5 complaint complaint NN cord-006870-f5w6fw6q 4948 6 in in IN cord-006870-f5w6fw6q 4948 7 majority majority NN cord-006870-f5w6fw6q 4948 8 of of IN cord-006870-f5w6fw6q 4948 9 patients patient NNS cord-006870-f5w6fw6q 4948 10 with with IN cord-006870-f5w6fw6q 4948 11 aSAH asah JJ cord-006870-f5w6fw6q 4948 12 and and CC cord-006870-f5w6fw6q 4948 13 is be VBZ cord-006870-f5w6fw6q 4948 14 known know VBN cord-006870-f5w6fw6q 4948 15 to to TO cord-006870-f5w6fw6q 4948 16 persist persist VB cord-006870-f5w6fw6q 4948 17 long long RB cord-006870-f5w6fw6q 4948 18 after after IN cord-006870-f5w6fw6q 4948 19 initial initial JJ cord-006870-f5w6fw6q 4948 20 ICU ICU NNP cord-006870-f5w6fw6q 4948 21 care care NN cord-006870-f5w6fw6q 4948 22 . . . cord-006870-f5w6fw6q 4949 1 Various various JJ cord-006870-f5w6fw6q 4949 2 medications medication NNS cord-006870-f5w6fw6q 4949 3 have have VBP cord-006870-f5w6fw6q 4949 4 been be VBN cord-006870-f5w6fw6q 4949 5 used use VBN cord-006870-f5w6fw6q 4949 6 for for IN cord-006870-f5w6fw6q 4949 7 control control NN cord-006870-f5w6fw6q 4949 8 of of IN cord-006870-f5w6fw6q 4949 9 headache headache NN cord-006870-f5w6fw6q 4949 10 with with IN cord-006870-f5w6fw6q 4949 11 major major JJ cord-006870-f5w6fw6q 4949 12 emphasis emphasis NN cord-006870-f5w6fw6q 4949 13 on on IN cord-006870-f5w6fw6q 4949 14 opiate opiate NN cord-006870-f5w6fw6q 4949 15 use use NN cord-006870-f5w6fw6q 4949 16 . . . cord-006870-f5w6fw6q 4950 1 History history NN cord-006870-f5w6fw6q 4950 2 of of IN cord-006870-f5w6fw6q 4950 3 a a DT cord-006870-f5w6fw6q 4950 4 prescription prescription NN cord-006870-f5w6fw6q 4950 5 for for IN cord-006870-f5w6fw6q 4950 6 an an DT cord-006870-f5w6fw6q 4950 7 opioid opioid JJ cord-006870-f5w6fw6q 4950 8 pain pain NN cord-006870-f5w6fw6q 4950 9 medication medication NN cord-006870-f5w6fw6q 4950 10 increases increase VBZ cord-006870-f5w6fw6q 4950 11 the the DT cord-006870-f5w6fw6q 4950 12 risk risk NN cord-006870-f5w6fw6q 4950 13 for for IN cord-006870-f5w6fw6q 4950 14 overdose overdose NN cord-006870-f5w6fw6q 4950 15 and and CC cord-006870-f5w6fw6q 4950 16 opioid opioid JJ cord-006870-f5w6fw6q 4950 17 use use NN cord-006870-f5w6fw6q 4950 18 disorder disorder NN cord-006870-f5w6fw6q 4950 19 . . . cord-006870-f5w6fw6q 4951 1 We -PRON- PRP cord-006870-f5w6fw6q 4951 2 looked look VBD cord-006870-f5w6fw6q 4951 3 at at IN cord-006870-f5w6fw6q 4951 4 prevalence prevalence NN cord-006870-f5w6fw6q 4951 5 of of IN cord-006870-f5w6fw6q 4951 6 opiate opiate NN cord-006870-f5w6fw6q 4951 7 use use NN cord-006870-f5w6fw6q 4951 8 at at IN cord-006870-f5w6fw6q 4951 9 discharge discharge NN cord-006870-f5w6fw6q 4951 10 and and CC cord-006870-f5w6fw6q 4951 11 its -PRON- PRP$ cord-006870-f5w6fw6q 4951 12 associated associate VBN cord-006870-f5w6fw6q 4951 13 factors factor NNS cord-006870-f5w6fw6q 4951 14 . . . cord-006870-f5w6fw6q 4952 1 Chart chart NN cord-006870-f5w6fw6q 4952 2 review review NN cord-006870-f5w6fw6q 4952 3 of of IN cord-006870-f5w6fw6q 4952 4 all all DT cord-006870-f5w6fw6q 4952 5 patients patient NNS cord-006870-f5w6fw6q 4952 6 admitted admit VBN cord-006870-f5w6fw6q 4952 7 in in IN cord-006870-f5w6fw6q 4952 8 a a DT cord-006870-f5w6fw6q 4952 9 tertiary tertiary JJ cord-006870-f5w6fw6q 4952 10 care care NN cord-006870-f5w6fw6q 4952 11 center center NN cord-006870-f5w6fw6q 4952 12 between between IN cord-006870-f5w6fw6q 4952 13 Jan Jan NNP cord-006870-f5w6fw6q 4952 14 2014 2014 CD cord-006870-f5w6fw6q 4952 15 and and CC cord-006870-f5w6fw6q 4952 16 March March NNP cord-006870-f5w6fw6q 4952 17 2016 2016 CD cord-006870-f5w6fw6q 4952 18 was be VBD cord-006870-f5w6fw6q 4952 19 carried carry VBN cord-006870-f5w6fw6q 4952 20 out out RP cord-006870-f5w6fw6q 4952 21 . . . cord-006870-f5w6fw6q 4953 1 Along along IN cord-006870-f5w6fw6q 4953 2 with with IN cord-006870-f5w6fw6q 4953 3 baseline baseline JJ cord-006870-f5w6fw6q 4953 4 demographic demographic JJ cord-006870-f5w6fw6q 4953 5 data datum NNS cord-006870-f5w6fw6q 4953 6 , , , cord-006870-f5w6fw6q 4953 7 information information NN cord-006870-f5w6fw6q 4953 8 about about IN cord-006870-f5w6fw6q 4953 9 use use NN cord-006870-f5w6fw6q 4953 10 of of IN cord-006870-f5w6fw6q 4953 11 pain pain NN cord-006870-f5w6fw6q 4953 12 scores score NNS cord-006870-f5w6fw6q 4953 13 , , , cord-006870-f5w6fw6q 4953 14 CSF CSF NNP cord-006870-f5w6fw6q 4953 15 diversion diversion NN cord-006870-f5w6fw6q 4953 16 , , , cord-006870-f5w6fw6q 4953 17 use use NN cord-006870-f5w6fw6q 4953 18 of of IN cord-006870-f5w6fw6q 4953 19 opiates opiate NNS cord-006870-f5w6fw6q 4953 20 , , , cord-006870-f5w6fw6q 4953 21 average average JJ cord-006870-f5w6fw6q 4953 22 morphine morphine NN cord-006870-f5w6fw6q 4953 23 equivalent equivalent JJ cord-006870-f5w6fw6q 4953 24 doses dose NNS cord-006870-f5w6fw6q 4953 25 , , , cord-006870-f5w6fw6q 4953 26 use use NN cord-006870-f5w6fw6q 4953 27 of of IN cord-006870-f5w6fw6q 4953 28 opiates opiate NNS cord-006870-f5w6fw6q 4953 29 at at IN cord-006870-f5w6fw6q 4953 30 discharge discharge NN cord-006870-f5w6fw6q 4953 31 and and CC cord-006870-f5w6fw6q 4953 32 destination destination NN cord-006870-f5w6fw6q 4953 33 at at IN cord-006870-f5w6fw6q 4953 34 discharge discharge NN cord-006870-f5w6fw6q 4953 35 was be VBD cord-006870-f5w6fw6q 4953 36 collected collect VBN cord-006870-f5w6fw6q 4953 37 . . . cord-006870-f5w6fw6q 4954 1 Analysis analysis NN cord-006870-f5w6fw6q 4954 2 was be VBD cord-006870-f5w6fw6q 4954 3 carried carry VBN cord-006870-f5w6fw6q 4954 4 out out RP cord-006870-f5w6fw6q 4954 5 using use VBG cord-006870-f5w6fw6q 4954 6 Microsoft Microsoft NNP cord-006870-f5w6fw6q 4954 7 Excel Excel NNP cord-006870-f5w6fw6q 4954 8 . . . cord-006870-f5w6fw6q 4955 1 The the DT cord-006870-f5w6fw6q 4955 2 study study NN cord-006870-f5w6fw6q 4955 3 was be VBD cord-006870-f5w6fw6q 4955 4 approved approve VBN cord-006870-f5w6fw6q 4955 5 by by IN cord-006870-f5w6fw6q 4955 6 hospital hospital NN cord-006870-f5w6fw6q 4955 7 IRB IRB NNP cord-006870-f5w6fw6q 4955 8 . . . cord-006870-f5w6fw6q 4956 1 52 52 CD cord-006870-f5w6fw6q 4956 2 patients patient NNS cord-006870-f5w6fw6q 4956 3 were be VBD cord-006870-f5w6fw6q 4956 4 admitted admit VBN cord-006870-f5w6fw6q 4956 5 with with IN cord-006870-f5w6fw6q 4956 6 aSAH asah JJ cord-006870-f5w6fw6q 4956 7 in in IN cord-006870-f5w6fw6q 4956 8 above above JJ cord-006870-f5w6fw6q 4956 9 period period NN cord-006870-f5w6fw6q 4956 10 ( ( -LRB- cord-006870-f5w6fw6q 4956 11 70 70 CD cord-006870-f5w6fw6q 4956 12 % % NN cord-006870-f5w6fw6q 4956 13 female female NN cord-006870-f5w6fw6q 4956 14 , , , cord-006870-f5w6fw6q 4956 15 Average Average NNP cord-006870-f5w6fw6q 4956 16 Age Age NNP cord-006870-f5w6fw6q 4956 17 : : : cord-006870-f5w6fw6q 4956 18 57 57 CD cord-006870-f5w6fw6q 4956 19 yrs yr NNS cord-006870-f5w6fw6q 4956 20 ) ) -RRB- cord-006870-f5w6fw6q 4956 21 . . . cord-006870-f5w6fw6q 4957 1 45 45 CD cord-006870-f5w6fw6q 4957 2 ( ( -LRB- cord-006870-f5w6fw6q 4957 3 62 62 CD cord-006870-f5w6fw6q 4957 4 % % NN cord-006870-f5w6fw6q 4957 5 home home NN cord-006870-f5w6fw6q 4957 6 , , , cord-006870-f5w6fw6q 4957 7 25 25 CD cord-006870-f5w6fw6q 4957 8 % % NN cord-006870-f5w6fw6q 4957 9 SNF SNF NNP cord-006870-f5w6fw6q 4957 10 ) ) -RRB- cord-006870-f5w6fw6q 4957 11 survived survive VBD cord-006870-f5w6fw6q 4957 12 to to TO cord-006870-f5w6fw6q 4957 13 discharge discharge VB cord-006870-f5w6fw6q 4957 14 . . . cord-006870-f5w6fw6q 4958 1 Among among IN cord-006870-f5w6fw6q 4958 2 survivors survivor NNS cord-006870-f5w6fw6q 4958 3 , , , cord-006870-f5w6fw6q 4958 4 40 40 CD cord-006870-f5w6fw6q 4958 5 % % NN cord-006870-f5w6fw6q 4958 6 required require VBD cord-006870-f5w6fw6q 4958 7 CSF csf NN cord-006870-f5w6fw6q 4958 8 diversion diversion NN cord-006870-f5w6fw6q 4958 9 for for IN cord-006870-f5w6fw6q 4958 10 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 4958 11 . . . cord-006870-f5w6fw6q 4959 1 All all DT cord-006870-f5w6fw6q 4959 2 people people NNS cord-006870-f5w6fw6q 4959 3 complained complain VBD cord-006870-f5w6fw6q 4959 4 of of IN cord-006870-f5w6fw6q 4959 5 pain pain NN cord-006870-f5w6fw6q 4959 6 on on IN cord-006870-f5w6fw6q 4959 7 presentation presentation NN cord-006870-f5w6fw6q 4959 8 and and CC cord-006870-f5w6fw6q 4959 9 were be VBD cord-006870-f5w6fw6q 4959 10 prescribed prescribe VBN cord-006870-f5w6fw6q 4959 11 opiates opiate NNS cord-006870-f5w6fw6q 4959 12 during during IN cord-006870-f5w6fw6q 4959 13 hospital hospital NN cord-006870-f5w6fw6q 4959 14 stay stay NN cord-006870-f5w6fw6q 4959 15 . . . cord-006870-f5w6fw6q 4960 1 Average average JJ cord-006870-f5w6fw6q 4960 2 oral oral JJ cord-006870-f5w6fw6q 4960 3 morphine morphine NN cord-006870-f5w6fw6q 4960 4 equivalent equivalent JJ cord-006870-f5w6fw6q 4960 5 doses dose NNS cord-006870-f5w6fw6q 4960 6 used use VBN cord-006870-f5w6fw6q 4960 7 was be VBD cord-006870-f5w6fw6q 4960 8 86 86 CD cord-006870-f5w6fw6q 4960 9 mg mg NN cord-006870-f5w6fw6q 4960 10 per per IN cord-006870-f5w6fw6q 4960 11 day day NN cord-006870-f5w6fw6q 4960 12 . . . cord-006870-f5w6fw6q 4961 1 25 25 CD cord-006870-f5w6fw6q 4961 2 ( ( -LRB- cord-006870-f5w6fw6q 4961 3 56 56 CD cord-006870-f5w6fw6q 4961 4 % % NN cord-006870-f5w6fw6q 4961 5 ) ) -RRB- cord-006870-f5w6fw6q 4961 6 patients patient NNS cord-006870-f5w6fw6q 4961 7 were be VBD cord-006870-f5w6fw6q 4961 8 prescribed prescribe VBN cord-006870-f5w6fw6q 4961 9 opiates opiate NNS cord-006870-f5w6fw6q 4961 10 on on IN cord-006870-f5w6fw6q 4961 11 discharge discharge NN cord-006870-f5w6fw6q 4961 12 . . . cord-006870-f5w6fw6q 4962 1 Alternative alternative JJ cord-006870-f5w6fw6q 4962 2 regimens regimen NNS cord-006870-f5w6fw6q 4962 3 included include VBD cord-006870-f5w6fw6q 4962 4 ( ( -LRB- cord-006870-f5w6fw6q 4962 5 2 2 CD cord-006870-f5w6fw6q 4962 6 patients patient NNS cord-006870-f5w6fw6q 4962 7 : : : cord-006870-f5w6fw6q 4962 8 tricyclic tricyclic NN cord-006870-f5w6fw6q 4962 9 antidepressant antidepressant NN cord-006870-f5w6fw6q 4962 10 ( ( -LRB- cord-006870-f5w6fw6q 4962 11 TCA TCA NNP cord-006870-f5w6fw6q 4962 12 ) ) -RRB- cord-006870-f5w6fw6q 4962 13 , , , cord-006870-f5w6fw6q 4962 14 2 2 CD cord-006870-f5w6fw6q 4962 15 opiate opiate NN cord-006870-f5w6fw6q 4962 16 + + CC cord-006870-f5w6fw6q 4962 17 TCA TCA NNP cord-006870-f5w6fw6q 4962 18 , , , cord-006870-f5w6fw6q 4962 19 1 1 CD cord-006870-f5w6fw6q 4962 20 acetaminophen acetaminophen NN cord-006870-f5w6fw6q 4962 21 , , , cord-006870-f5w6fw6q 4962 22 1 1 CD cord-006870-f5w6fw6q 4962 23 dexamethasone dexamethasone NN cord-006870-f5w6fw6q 4962 24 , , , cord-006870-f5w6fw6q 4962 25 TCA TCA NNP cord-006870-f5w6fw6q 4962 26 and and CC cord-006870-f5w6fw6q 4962 27 opiates opiate NNS cord-006870-f5w6fw6q 4962 28 ) ) -RRB- cord-006870-f5w6fw6q 4962 29 . . . cord-006870-f5w6fw6q 4963 1 Most Most JJS cord-006870-f5w6fw6q 4963 2 common common JJ cord-006870-f5w6fw6q 4963 3 prescribed prescribe VBN cord-006870-f5w6fw6q 4963 4 form form NN cord-006870-f5w6fw6q 4963 5 of of IN cord-006870-f5w6fw6q 4963 6 opiate opiate NN cord-006870-f5w6fw6q 4963 7 was be VBD cord-006870-f5w6fw6q 4963 8 oxycodone oxycodone NN cord-006870-f5w6fw6q 4963 9 . . . cord-006870-f5w6fw6q 4964 1 There there EX cord-006870-f5w6fw6q 4964 2 was be VBD cord-006870-f5w6fw6q 4964 3 no no DT cord-006870-f5w6fw6q 4964 4 significant significant JJ cord-006870-f5w6fw6q 4964 5 association association NN cord-006870-f5w6fw6q 4964 6 between between IN cord-006870-f5w6fw6q 4964 7 opiate opiate NN cord-006870-f5w6fw6q 4964 8 use use NN cord-006870-f5w6fw6q 4964 9 / / SYM cord-006870-f5w6fw6q 4964 10 morphine morphine NN cord-006870-f5w6fw6q 4964 11 dosing dosing NN cord-006870-f5w6fw6q 4964 12 and and CC cord-006870-f5w6fw6q 4964 13 age age NN cord-006870-f5w6fw6q 4964 14 , , , cord-006870-f5w6fw6q 4964 15 gender gender NN cord-006870-f5w6fw6q 4964 16 , , , cord-006870-f5w6fw6q 4964 17 final final JJ cord-006870-f5w6fw6q 4964 18 disposition disposition NN cord-006870-f5w6fw6q 4964 19 and and CC cord-006870-f5w6fw6q 4964 20 CSF CSF NNP cord-006870-f5w6fw6q 4964 21 diversion diversion NN cord-006870-f5w6fw6q 4964 22 , , , cord-006870-f5w6fw6q 4964 23 Opiate opiate JJ cord-006870-f5w6fw6q 4964 24 prescription prescription NN cord-006870-f5w6fw6q 4964 25 at at IN cord-006870-f5w6fw6q 4964 26 discharge discharge NN cord-006870-f5w6fw6q 4964 27 is be VBZ cord-006870-f5w6fw6q 4964 28 common common JJ cord-006870-f5w6fw6q 4964 29 in in IN cord-006870-f5w6fw6q 4964 30 patients patient NNS cord-006870-f5w6fw6q 4964 31 with with IN cord-006870-f5w6fw6q 4964 32 aSAH asah JJ cord-006870-f5w6fw6q 4964 33 . . . cord-006870-f5w6fw6q 4965 1 No no DT cord-006870-f5w6fw6q 4965 2 clinical clinical JJ cord-006870-f5w6fw6q 4965 3 characteristic characteristic NN cord-006870-f5w6fw6q 4965 4 seem seem VBP cord-006870-f5w6fw6q 4965 5 to to TO cord-006870-f5w6fw6q 4965 6 predict predict VB cord-006870-f5w6fw6q 4965 7 analgesic analgesic JJ cord-006870-f5w6fw6q 4965 8 need need NN cord-006870-f5w6fw6q 4965 9 at at IN cord-006870-f5w6fw6q 4965 10 discharge discharge NN cord-006870-f5w6fw6q 4965 11 . . . cord-006870-f5w6fw6q 4966 1 Little little JJ cord-006870-f5w6fw6q 4966 2 data data NN cord-006870-f5w6fw6q 4966 3 exists exist VBZ cord-006870-f5w6fw6q 4966 4 about about IN cord-006870-f5w6fw6q 4966 5 better well JJR cord-006870-f5w6fw6q 4966 6 alternatives alternative NNS cord-006870-f5w6fw6q 4966 7 leading lead VBG cord-006870-f5w6fw6q 4966 8 to to IN cord-006870-f5w6fw6q 4966 9 variety variety NN cord-006870-f5w6fw6q 4966 10 of of IN cord-006870-f5w6fw6q 4966 11 treatment treatment NN cord-006870-f5w6fw6q 4966 12 approaches approach NNS cord-006870-f5w6fw6q 4966 13 . . . cord-006870-f5w6fw6q 4967 1 Further further RB cord-006870-f5w6fw6q 4967 2 controlled control VBN cord-006870-f5w6fw6q 4967 3 trials trial NNS cord-006870-f5w6fw6q 4967 4 are be VBP cord-006870-f5w6fw6q 4967 5 needed need VBN cord-006870-f5w6fw6q 4967 6 to to TO cord-006870-f5w6fw6q 4967 7 decrease decrease VB cord-006870-f5w6fw6q 4967 8 opiate opiate NN cord-006870-f5w6fw6q 4967 9 use use NN cord-006870-f5w6fw6q 4967 10 and and CC cord-006870-f5w6fw6q 4967 11 prevent prevent VB cord-006870-f5w6fw6q 4967 12 adverse adverse JJ cord-006870-f5w6fw6q 4967 13 effects effect NNS cord-006870-f5w6fw6q 4967 14 Delayed delay VBN cord-006870-f5w6fw6q 4967 15 Cerebral Cerebral NNP cord-006870-f5w6fw6q 4967 16 Ischemia Ischemia NNP cord-006870-f5w6fw6q 4967 17 ( ( -LRB- cord-006870-f5w6fw6q 4967 18 DCI DCI NNP cord-006870-f5w6fw6q 4967 19 ) ) -RRB- cord-006870-f5w6fw6q 4967 20 in in IN cord-006870-f5w6fw6q 4967 21 SAH SAH NNP cord-006870-f5w6fw6q 4967 22 has have VBZ cord-006870-f5w6fw6q 4967 23 been be VBN cord-006870-f5w6fw6q 4967 24 associated associate VBN cord-006870-f5w6fw6q 4967 25 with with IN cord-006870-f5w6fw6q 4967 26 vasospasm vasospasm NN cord-006870-f5w6fw6q 4967 27 - - HYPH cord-006870-f5w6fw6q 4967 28 dependent dependent JJ cord-006870-f5w6fw6q 4967 29 and and CC cord-006870-f5w6fw6q 4967 30 vasospasmindependent vasospasmindependent NN cord-006870-f5w6fw6q 4967 31 phenomena phenomenon NNS cord-006870-f5w6fw6q 4967 32 . . . cord-006870-f5w6fw6q 4968 1 For for IN cord-006870-f5w6fw6q 4968 2 more more JJR cord-006870-f5w6fw6q 4968 3 than than IN cord-006870-f5w6fw6q 4968 4 40 40 CD cord-006870-f5w6fw6q 4968 5 years year NNS cord-006870-f5w6fw6q 4968 6 isolated isolate VBN cord-006870-f5w6fw6q 4968 7 hemostasis hemostasis NN cord-006870-f5w6fw6q 4968 8 disorders disorder NNS cord-006870-f5w6fw6q 4968 9 have have VBP cord-006870-f5w6fw6q 4968 10 been be VBN cord-006870-f5w6fw6q 4968 11 reported report VBN cord-006870-f5w6fw6q 4968 12 in in IN cord-006870-f5w6fw6q 4968 13 these these DT cord-006870-f5w6fw6q 4968 14 patients patient NNS cord-006870-f5w6fw6q 4968 15 . . . cord-006870-f5w6fw6q 4969 1 The the DT cord-006870-f5w6fw6q 4969 2 objective objective NN cord-006870-f5w6fw6q 4969 3 of of IN cord-006870-f5w6fw6q 4969 4 this this DT cord-006870-f5w6fw6q 4969 5 systematic systematic JJ cord-006870-f5w6fw6q 4969 6 review review NN cord-006870-f5w6fw6q 4969 7 is be VBZ cord-006870-f5w6fw6q 4969 8 to to TO cord-006870-f5w6fw6q 4969 9 describe describe VB cord-006870-f5w6fw6q 4969 10 the the DT cord-006870-f5w6fw6q 4969 11 natural natural JJ cord-006870-f5w6fw6q 4969 12 history history NN cord-006870-f5w6fw6q 4969 13 of of IN cord-006870-f5w6fw6q 4969 14 hemostasis hemostasis NN cord-006870-f5w6fw6q 4969 15 in in IN cord-006870-f5w6fw6q 4969 16 SAH SAH NNP cord-006870-f5w6fw6q 4969 17 . . . cord-006870-f5w6fw6q 4970 1 We -PRON- PRP cord-006870-f5w6fw6q 4970 2 systematically systematically RB cord-006870-f5w6fw6q 4970 3 reviewed review VBD cord-006870-f5w6fw6q 4970 4 the the DT cord-006870-f5w6fw6q 4970 5 Medline Medline NNP cord-006870-f5w6fw6q 4970 6 , , , cord-006870-f5w6fw6q 4970 7 EMBASE EMBASE NNP cord-006870-f5w6fw6q 4970 8 , , , cord-006870-f5w6fw6q 4970 9 Cochrane Cochrane NNP cord-006870-f5w6fw6q 4970 10 and and CC cord-006870-f5w6fw6q 4970 11 Lilacs Lilacs NNP cord-006870-f5w6fw6q 4970 12 databases database NNS cord-006870-f5w6fw6q 4970 13 using use VBG cord-006870-f5w6fw6q 4970 14 controlled control VBN cord-006870-f5w6fw6q 4970 15 language language NN cord-006870-f5w6fw6q 4970 16 and and CC cord-006870-f5w6fw6q 4970 17 the the DT cord-006870-f5w6fw6q 4970 18 PRISMA PRISMA NNP cord-006870-f5w6fw6q 4970 19 statement statement NN cord-006870-f5w6fw6q 4970 20 and and CC cord-006870-f5w6fw6q 4970 21 included include VBD cord-006870-f5w6fw6q 4970 22 studies study NNS cord-006870-f5w6fw6q 4970 23 on on IN cord-006870-f5w6fw6q 4970 24 spontaneous spontaneous JJ cord-006870-f5w6fw6q 4970 25 SAH SAH NNP cord-006870-f5w6fw6q 4970 26 analyzing analyze VBG cord-006870-f5w6fw6q 4970 27 any any DT cord-006870-f5w6fw6q 4970 28 hemostasis hemostasis NN cord-006870-f5w6fw6q 4970 29 parameter parameter NN cord-006870-f5w6fw6q 4970 30 . . . cord-006870-f5w6fw6q 4971 1 We -PRON- PRP cord-006870-f5w6fw6q 4971 2 screened screen VBD cord-006870-f5w6fw6q 4971 3 1794 1794 CD cord-006870-f5w6fw6q 4971 4 titles title NNS cord-006870-f5w6fw6q 4971 5 , , , cord-006870-f5w6fw6q 4971 6 of of IN cord-006870-f5w6fw6q 4971 7 which which WDT cord-006870-f5w6fw6q 4971 8 57 57 CD cord-006870-f5w6fw6q 4971 9 observational observational JJ cord-006870-f5w6fw6q 4971 10 were be VBD cord-006870-f5w6fw6q 4971 11 included include VBN cord-006870-f5w6fw6q 4971 12 . . . cord-006870-f5w6fw6q 4972 1 Evidence evidence NN cord-006870-f5w6fw6q 4972 2 was be VBD cord-006870-f5w6fw6q 4972 3 evaluated evaluate VBN cord-006870-f5w6fw6q 4972 4 following follow VBG cord-006870-f5w6fw6q 4972 5 the the DT cord-006870-f5w6fw6q 4972 6 STROBE STROBE NNP cord-006870-f5w6fw6q 4972 7 Statement Statement NNP cord-006870-f5w6fw6q 4972 8 . . . cord-006870-f5w6fw6q 4973 1 No no DT cord-006870-f5w6fw6q 4973 2 meta meta NNP cord-006870-f5w6fw6q 4973 3 - - HYPH cord-006870-f5w6fw6q 4973 4 analysis analysis NN cord-006870-f5w6fw6q 4973 5 was be VBD cord-006870-f5w6fw6q 4973 6 attempted attempt VBN cord-006870-f5w6fw6q 4973 7 because because IN cord-006870-f5w6fw6q 4973 8 of of IN cord-006870-f5w6fw6q 4973 9 the the DT cord-006870-f5w6fw6q 4973 10 methodological methodological JJ cord-006870-f5w6fw6q 4973 11 nature nature NN cord-006870-f5w6fw6q 4973 12 and and CC cord-006870-f5w6fw6q 4973 13 heterogeneity heterogeneity NN cord-006870-f5w6fw6q 4973 14 of of IN cord-006870-f5w6fw6q 4973 15 the the DT cord-006870-f5w6fw6q 4973 16 studies study NNS cord-006870-f5w6fw6q 4973 17 . . . cord-006870-f5w6fw6q 4974 1 Hemostasis Hemostasis NNP cord-006870-f5w6fw6q 4974 2 is be VBZ cord-006870-f5w6fw6q 4974 3 profoundly profoundly RB cord-006870-f5w6fw6q 4974 4 altered alter VBN cord-006870-f5w6fw6q 4974 5 during during IN cord-006870-f5w6fw6q 4974 6 the the DT cord-006870-f5w6fw6q 4974 7 first first JJ cord-006870-f5w6fw6q 4974 8 hours hour NNS cord-006870-f5w6fw6q 4974 9 after after IN cord-006870-f5w6fw6q 4974 10 bleeding bleed VBG cord-006870-f5w6fw6q 4974 11 , , , cord-006870-f5w6fw6q 4974 12 with with IN cord-006870-f5w6fw6q 4974 13 several several JJ cord-006870-f5w6fw6q 4974 14 alterations alteration NNS cord-006870-f5w6fw6q 4974 15 noted note VBD cord-006870-f5w6fw6q 4974 16 including include VBG cord-006870-f5w6fw6q 4974 17 a a DT cord-006870-f5w6fw6q 4974 18 hypercoagulable hypercoagulable JJ cord-006870-f5w6fw6q 4974 19 state state NN cord-006870-f5w6fw6q 4974 20 concomitant concomitant JJ cord-006870-f5w6fw6q 4974 21 with with IN cord-006870-f5w6fw6q 4974 22 increased increase VBN cord-006870-f5w6fw6q 4974 23 fibrinolysis fibrinolysis NN cord-006870-f5w6fw6q 4974 24 activation activation NN cord-006870-f5w6fw6q 4974 25 and and CC cord-006870-f5w6fw6q 4974 26 reduced reduced JJ cord-006870-f5w6fw6q 4974 27 clot clot NN cord-006870-f5w6fw6q 4974 28 stability stability NN cord-006870-f5w6fw6q 4974 29 . . . cord-006870-f5w6fw6q 4975 1 Direct direct JJ cord-006870-f5w6fw6q 4975 2 and and CC cord-006870-f5w6fw6q 4975 3 indirect indirect JJ cord-006870-f5w6fw6q 4975 4 coagulation coagulation NN cord-006870-f5w6fw6q 4975 5 markers marker NNS cord-006870-f5w6fw6q 4975 6 show show VBP cord-006870-f5w6fw6q 4975 7 a a DT cord-006870-f5w6fw6q 4975 8 trend trend NN cord-006870-f5w6fw6q 4975 9 towards towards IN cord-006870-f5w6fw6q 4975 10 normalization normalization NN cord-006870-f5w6fw6q 4975 11 of of IN cord-006870-f5w6fw6q 4975 12 hemostasis hemostasis NN cord-006870-f5w6fw6q 4975 13 in in IN cord-006870-f5w6fw6q 4975 14 the the DT cord-006870-f5w6fw6q 4975 15 first first JJ cord-006870-f5w6fw6q 4975 16 2 2 CD cord-006870-f5w6fw6q 4975 17 to to TO cord-006870-f5w6fw6q 4975 18 3 3 CD cord-006870-f5w6fw6q 4975 19 days day NNS cord-006870-f5w6fw6q 4975 20 . . . cord-006870-f5w6fw6q 4976 1 Platelet platelet NN cord-006870-f5w6fw6q 4976 2 count count NN cord-006870-f5w6fw6q 4976 3 decreases decrease VBZ cord-006870-f5w6fw6q 4976 4 with with IN cord-006870-f5w6fw6q 4976 5 a a DT cord-006870-f5w6fw6q 4976 6 nadir nadir NN cord-006870-f5w6fw6q 4976 7 4 4 CD cord-006870-f5w6fw6q 4976 8 to to TO cord-006870-f5w6fw6q 4976 9 6 6 CD cord-006870-f5w6fw6q 4976 10 days day NNS cord-006870-f5w6fw6q 4976 11 after after IN cord-006870-f5w6fw6q 4976 12 bleeding bleed VBG cord-006870-f5w6fw6q 4976 13 and and CC cord-006870-f5w6fw6q 4976 14 a a DT cord-006870-f5w6fw6q 4976 15 recovery recovery NN cord-006870-f5w6fw6q 4976 16 in in IN cord-006870-f5w6fw6q 4976 17 the the DT cord-006870-f5w6fw6q 4976 18 following follow VBG cord-006870-f5w6fw6q 4976 19 weeks week NNS cord-006870-f5w6fw6q 4976 20 . . . cord-006870-f5w6fw6q 4977 1 A a DT cord-006870-f5w6fw6q 4977 2 later later JJ cord-006870-f5w6fw6q 4977 3 nadir nadir NN cord-006870-f5w6fw6q 4977 4 is be VBZ cord-006870-f5w6fw6q 4977 5 associated associate VBN cord-006870-f5w6fw6q 4977 6 with with IN cord-006870-f5w6fw6q 4977 7 DCI DCI NNP cord-006870-f5w6fw6q 4977 8 . . . cord-006870-f5w6fw6q 4978 1 Platelet platelet NN cord-006870-f5w6fw6q 4978 2 aggregability aggregability NN cord-006870-f5w6fw6q 4978 3 is be VBZ cord-006870-f5w6fw6q 4978 4 consistently consistently RB cord-006870-f5w6fw6q 4978 5 decreased decrease VBN cord-006870-f5w6fw6q 4978 6 in in IN cord-006870-f5w6fw6q 4978 7 the the DT cord-006870-f5w6fw6q 4978 8 first first JJ cord-006870-f5w6fw6q 4978 9 few few JJ cord-006870-f5w6fw6q 4978 10 days day NNS cord-006870-f5w6fw6q 4978 11 , , , cord-006870-f5w6fw6q 4978 12 regaining regain VBG cord-006870-f5w6fw6q 4978 13 its -PRON- PRP$ cord-006870-f5w6fw6q 4978 14 normal normal JJ cord-006870-f5w6fw6q 4978 15 function function NN cord-006870-f5w6fw6q 4978 16 around around IN cord-006870-f5w6fw6q 4978 17 the the DT cord-006870-f5w6fw6q 4978 18 second second JJ cord-006870-f5w6fw6q 4978 19 week week NN cord-006870-f5w6fw6q 4978 20 after after IN cord-006870-f5w6fw6q 4978 21 bleeding bleed VBG cord-006870-f5w6fw6q 4978 22 . . . cord-006870-f5w6fw6q 4979 1 In in IN cord-006870-f5w6fw6q 4979 2 addition addition NN cord-006870-f5w6fw6q 4979 3 , , , cord-006870-f5w6fw6q 4979 4 the the DT cord-006870-f5w6fw6q 4979 5 persistence persistence NN cord-006870-f5w6fw6q 4979 6 of of IN cord-006870-f5w6fw6q 4979 7 these these DT cord-006870-f5w6fw6q 4979 8 alterations alteration NNS cord-006870-f5w6fw6q 4979 9 or or CC cord-006870-f5w6fw6q 4979 10 the the DT cord-006870-f5w6fw6q 4979 11 presence presence NN cord-006870-f5w6fw6q 4979 12 of of IN cord-006870-f5w6fw6q 4979 13 a a DT cord-006870-f5w6fw6q 4979 14 second second JJ cord-006870-f5w6fw6q 4979 15 peak peak NN cord-006870-f5w6fw6q 4979 16 in in IN cord-006870-f5w6fw6q 4979 17 pro pro JJ cord-006870-f5w6fw6q 4979 18 - - JJ cord-006870-f5w6fw6q 4979 19 coagulatory coagulatory JJ cord-006870-f5w6fw6q 4979 20 activity activity NN cord-006870-f5w6fw6q 4979 21 is be VBZ cord-006870-f5w6fw6q 4979 22 associated associate VBN cord-006870-f5w6fw6q 4979 23 consistently consistently RB cord-006870-f5w6fw6q 4979 24 with with IN cord-006870-f5w6fw6q 4979 25 DCI DCI NNP cord-006870-f5w6fw6q 4979 26 and and CC cord-006870-f5w6fw6q 4979 27 worse bad JJR cord-006870-f5w6fw6q 4979 28 functional functional JJ cord-006870-f5w6fw6q 4979 29 outcomes outcome NNS cord-006870-f5w6fw6q 4979 30 . . . cord-006870-f5w6fw6q 4980 1 The the DT cord-006870-f5w6fw6q 4980 2 hyperacute hyperacute JJ cord-006870-f5w6fw6q 4980 3 phase phase NN cord-006870-f5w6fw6q 4980 4 of of IN cord-006870-f5w6fw6q 4980 5 SAH SAH NNP cord-006870-f5w6fw6q 4980 6 is be VBZ cord-006870-f5w6fw6q 4980 7 characterized characterize VBN cord-006870-f5w6fw6q 4980 8 by by IN cord-006870-f5w6fw6q 4980 9 a a DT cord-006870-f5w6fw6q 4980 10 profound profound JJ cord-006870-f5w6fw6q 4980 11 activation activation NN cord-006870-f5w6fw6q 4980 12 in in IN cord-006870-f5w6fw6q 4980 13 hemostasis hemostasis NN cord-006870-f5w6fw6q 4980 14 with with IN cord-006870-f5w6fw6q 4980 15 reduced reduce VBN cord-006870-f5w6fw6q 4980 16 clot clot NN cord-006870-f5w6fw6q 4980 17 stability stability NN cord-006870-f5w6fw6q 4980 18 , , , cord-006870-f5w6fw6q 4980 19 probably probably RB cord-006870-f5w6fw6q 4980 20 due due IN cord-006870-f5w6fw6q 4980 21 to to IN cord-006870-f5w6fw6q 4980 22 an an DT cord-006870-f5w6fw6q 4980 23 increase increase NN cord-006870-f5w6fw6q 4980 24 in in IN cord-006870-f5w6fw6q 4980 25 the the DT cord-006870-f5w6fw6q 4980 26 fibrinolytic fibrinolytic JJ cord-006870-f5w6fw6q 4980 27 pathways pathway NNS cord-006870-f5w6fw6q 4980 28 . . . cord-006870-f5w6fw6q 4981 1 On on IN cord-006870-f5w6fw6q 4981 2 the the DT cord-006870-f5w6fw6q 4981 3 second second JJ cord-006870-f5w6fw6q 4981 4 day day NN cord-006870-f5w6fw6q 4981 5 post post NN cord-006870-f5w6fw6q 4981 6 - - JJ cord-006870-f5w6fw6q 4981 7 bleeding bleeding JJ cord-006870-f5w6fw6q 4981 8 , , , cord-006870-f5w6fw6q 4981 9 a a DT cord-006870-f5w6fw6q 4981 10 slow slow JJ cord-006870-f5w6fw6q 4981 11 trend trend NN cord-006870-f5w6fw6q 4981 12 towards towards IN cord-006870-f5w6fw6q 4981 13 normalization normalization NN cord-006870-f5w6fw6q 4981 14 takes take VBZ cord-006870-f5w6fw6q 4981 15 place place NN cord-006870-f5w6fw6q 4981 16 , , , cord-006870-f5w6fw6q 4981 17 except except IN cord-006870-f5w6fw6q 4981 18 in in IN cord-006870-f5w6fw6q 4981 19 patients patient NNS cord-006870-f5w6fw6q 4981 20 evolving evolve VBG cord-006870-f5w6fw6q 4981 21 towards towards IN cord-006870-f5w6fw6q 4981 22 DCI DCI NNP cord-006870-f5w6fw6q 4981 23 . . . cord-006870-f5w6fw6q 4982 1 Further further JJ cord-006870-f5w6fw6q 4982 2 research research NN cord-006870-f5w6fw6q 4982 3 on on IN cord-006870-f5w6fw6q 4982 4 the the DT cord-006870-f5w6fw6q 4982 5 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 4982 6 manipulation manipulation NN cord-006870-f5w6fw6q 4982 7 of of IN cord-006870-f5w6fw6q 4982 8 hemostasis hemostasis NN cord-006870-f5w6fw6q 4982 9 in in IN cord-006870-f5w6fw6q 4982 10 SAH SAH NNP cord-006870-f5w6fw6q 4982 11 might may MD cord-006870-f5w6fw6q 4982 12 be be VB cord-006870-f5w6fw6q 4982 13 warranted warrant VBN cord-006870-f5w6fw6q 4982 14 to to TO cord-006870-f5w6fw6q 4982 15 decrease decrease VB cord-006870-f5w6fw6q 4982 16 DCI DCI NNP cord-006870-f5w6fw6q 4982 17 and and CC cord-006870-f5w6fw6q 4982 18 improve improve VB cord-006870-f5w6fw6q 4982 19 outcomes outcome NNS cord-006870-f5w6fw6q 4982 20 in in IN cord-006870-f5w6fw6q 4982 21 this this DT cord-006870-f5w6fw6q 4982 22 population population NN cord-006870-f5w6fw6q 4982 23 . . . cord-006870-f5w6fw6q 4983 1 Hypertonic Hypertonic NNP cord-006870-f5w6fw6q 4983 2 saline(HTS saline(HTS NNP cord-006870-f5w6fw6q 4983 3 ) ) -RRB- cord-006870-f5w6fw6q 4983 4 is be VBZ cord-006870-f5w6fw6q 4983 5 a a DT cord-006870-f5w6fw6q 4983 6 treatment treatment NN cord-006870-f5w6fw6q 4983 7 for for IN cord-006870-f5w6fw6q 4983 8 SAH SAH NNP cord-006870-f5w6fw6q 4983 9 - - HYPH cord-006870-f5w6fw6q 4983 10 related relate VBN cord-006870-f5w6fw6q 4983 11 cerebral cerebral JJ cord-006870-f5w6fw6q 4983 12 edema edema NN cord-006870-f5w6fw6q 4983 13 , , , cord-006870-f5w6fw6q 4983 14 administered administer VBN cord-006870-f5w6fw6q 4983 15 to to TO cord-006870-f5w6fw6q 4983 16 improve improve VB cord-006870-f5w6fw6q 4983 17 cerebral cerebral JJ cord-006870-f5w6fw6q 4983 18 perfusion perfusion NN cord-006870-f5w6fw6q 4983 19 and and CC cord-006870-f5w6fw6q 4983 20 reduce reduce VB cord-006870-f5w6fw6q 4983 21 brain brain NN cord-006870-f5w6fw6q 4983 22 injury injury NN cord-006870-f5w6fw6q 4983 23 . . . cord-006870-f5w6fw6q 4984 1 HTS HTS NNP cord-006870-f5w6fw6q 4984 2 a a DT cord-006870-f5w6fw6q 4984 3 supra supra NN cord-006870-f5w6fw6q 4984 4 - - HYPH cord-006870-f5w6fw6q 4984 5 physiological physiological JJ cord-006870-f5w6fw6q 4984 6 chloride chloride NN cord-006870-f5w6fw6q 4984 7 concentration concentration NN cord-006870-f5w6fw6q 4984 8 that that WDT cord-006870-f5w6fw6q 4984 9 can can MD cord-006870-f5w6fw6q 4984 10 contribute contribute VB cord-006870-f5w6fw6q 4984 11 to to IN cord-006870-f5w6fw6q 4984 12 acute acute JJ cord-006870-f5w6fw6q 4984 13 kidney kidney NN cord-006870-f5w6fw6q 4984 14 injury injury NN cord-006870-f5w6fw6q 4984 15 which which WDT cord-006870-f5w6fw6q 4984 16 can can MD cord-006870-f5w6fw6q 4984 17 lead lead VB cord-006870-f5w6fw6q 4984 18 to to IN cord-006870-f5w6fw6q 4984 19 a a DT cord-006870-f5w6fw6q 4984 20 poor poor JJ cord-006870-f5w6fw6q 4984 21 outcome outcome NN cord-006870-f5w6fw6q 4984 22 . . . cord-006870-f5w6fw6q 4985 1 In in IN cord-006870-f5w6fw6q 4985 2 a a DT cord-006870-f5w6fw6q 4985 3 previously previously RB cord-006870-f5w6fw6q 4985 4 published publish VBN cord-006870-f5w6fw6q 4985 5 single single JJ cord-006870-f5w6fw6q 4985 6 - - HYPH cord-006870-f5w6fw6q 4985 7 center center NN cord-006870-f5w6fw6q 4985 8 cohort cohort NN cord-006870-f5w6fw6q 4985 9 of of IN cord-006870-f5w6fw6q 4985 10 1,267l 1,267l CD cord-006870-f5w6fw6q 4985 11 SAH SAH NNP cord-006870-f5w6fw6q 4985 12 patients patient NNS cord-006870-f5w6fw6q 4985 13 , , , cord-006870-f5w6fw6q 4985 14 16.7 16.7 CD cord-006870-f5w6fw6q 4985 15 % % NN cord-006870-f5w6fw6q 4985 16 developed develop VBD cord-006870-f5w6fw6q 4985 17 acute acute JJ cord-006870-f5w6fw6q 4985 18 kidney kidney NN cord-006870-f5w6fw6q 4985 19 injury injury NN cord-006870-f5w6fw6q 4985 20 ( ( -LRB- cord-006870-f5w6fw6q 4985 21 AKI AKI NNP cord-006870-f5w6fw6q 4985 22 ) ) -RRB- cord-006870-f5w6fw6q 4985 23 . . . cord-006870-f5w6fw6q 4986 1 Hyperchloremia Hyperchloremia NNP cord-006870-f5w6fw6q 4986 2 , , , cord-006870-f5w6fw6q 4986 3 but but CC cord-006870-f5w6fw6q 4986 4 not not RB cord-006870-f5w6fw6q 4986 5 hypernatremia hypernatremia NN cord-006870-f5w6fw6q 4986 6 , , , cord-006870-f5w6fw6q 4986 7 was be VBD cord-006870-f5w6fw6q 4986 8 correlated correlate VBN cord-006870-f5w6fw6q 4986 9 with with IN cord-006870-f5w6fw6q 4986 10 an an DT cord-006870-f5w6fw6q 4986 11 increased increase VBN cord-006870-f5w6fw6q 4986 12 risk risk NN cord-006870-f5w6fw6q 4986 13 to to TO cord-006870-f5w6fw6q 4986 14 develop develop VB cord-006870-f5w6fw6q 4986 15 AKI AKI NNP cord-006870-f5w6fw6q 4986 16 ( ( -LRB- cord-006870-f5w6fw6q 4986 17 O.R. O.R. NNP cord-006870-f5w6fw6q 4986 18 7.39 7.39 CD cord-006870-f5w6fw6q 4986 19 ) ) -RRB- cord-006870-f5w6fw6q 4986 20 . . . cord-006870-f5w6fw6q 4987 1 AKI AKI NNP cord-006870-f5w6fw6q 4987 2 was be VBD cord-006870-f5w6fw6q 4987 3 correlated correlate VBN cord-006870-f5w6fw6q 4987 4 with with IN cord-006870-f5w6fw6q 4987 5 increased increase VBN cord-006870-f5w6fw6q 4987 6 mortality mortality NN cord-006870-f5w6fw6q 4987 7 . . . cord-006870-f5w6fw6q 4988 1 A a DT cord-006870-f5w6fw6q 4988 2 secondary secondary JJ cord-006870-f5w6fw6q 4988 3 analysis analysis NN cord-006870-f5w6fw6q 4988 4 of of IN cord-006870-f5w6fw6q 4988 5 the the DT cord-006870-f5w6fw6q 4988 6 aforementioned aforementioned JJ cord-006870-f5w6fw6q 4988 7 SAH SAH NNP cord-006870-f5w6fw6q 4988 8 patient patient JJ cord-006870-f5w6fw6q 4988 9 cohort cohort NN cord-006870-f5w6fw6q 4988 10 ( ( -LRB- cord-006870-f5w6fw6q 4988 11 2009 2009 CD cord-006870-f5w6fw6q 4988 12 ) ) -RRB- cord-006870-f5w6fw6q 4988 13 ( ( -LRB- cord-006870-f5w6fw6q 4988 14 2010 2010 CD cord-006870-f5w6fw6q 4988 15 ) ) -RRB- cord-006870-f5w6fw6q 4989 1 ( ( -LRB- cord-006870-f5w6fw6q 4989 2 2011 2011 CD cord-006870-f5w6fw6q 4989 3 ) ) -RRB- cord-006870-f5w6fw6q 4990 1 ( ( -LRB- cord-006870-f5w6fw6q 4990 2 2012 2012 CD cord-006870-f5w6fw6q 4990 3 ) ) -RRB- cord-006870-f5w6fw6q 4991 1 ( ( -LRB- cord-006870-f5w6fw6q 4991 2 2013 2013 CD cord-006870-f5w6fw6q 4991 3 ) ) -RRB- cord-006870-f5w6fw6q 4992 1 ( ( -LRB- cord-006870-f5w6fw6q 4992 2 2014 2014 CD cord-006870-f5w6fw6q 4992 3 ) ) -RRB- cord-006870-f5w6fw6q 4992 4 , , , cord-006870-f5w6fw6q 4992 5 was be VBD cord-006870-f5w6fw6q 4992 6 analyzed analyze VBN cord-006870-f5w6fw6q 4992 7 . . . cord-006870-f5w6fw6q 4993 1 Trends trend NNS cord-006870-f5w6fw6q 4993 2 of of IN cord-006870-f5w6fw6q 4993 3 acute acute JJ cord-006870-f5w6fw6q 4993 4 kidney kidney NN cord-006870-f5w6fw6q 4993 5 injury injury NN cord-006870-f5w6fw6q 4993 6 were be VBD cord-006870-f5w6fw6q 4993 7 evaluated evaluate VBN cord-006870-f5w6fw6q 4993 8 in in IN cord-006870-f5w6fw6q 4993 9 relation relation NN cord-006870-f5w6fw6q 4993 10 to to IN cord-006870-f5w6fw6q 4993 11 the the DT cord-006870-f5w6fw6q 4993 12 burden burden NN cord-006870-f5w6fw6q 4993 13 of of IN cord-006870-f5w6fw6q 4993 14 exposure exposure NN cord-006870-f5w6fw6q 4993 15 to to IN cord-006870-f5w6fw6q 4993 16 intravenous intravenous JJ cord-006870-f5w6fw6q 4993 17 chloride chloride NN cord-006870-f5w6fw6q 4993 18 , , , cord-006870-f5w6fw6q 4993 19 as as RB cord-006870-f5w6fw6q 4993 20 well well RB cord-006870-f5w6fw6q 4993 21 as as IN cord-006870-f5w6fw6q 4993 22 serum serum NN cord-006870-f5w6fw6q 4993 23 levels level NNS cord-006870-f5w6fw6q 4993 24 of of IN cord-006870-f5w6fw6q 4993 25 sodium sodium NN cord-006870-f5w6fw6q 4993 26 and and CC cord-006870-f5w6fw6q 4993 27 chloride chloride NN cord-006870-f5w6fw6q 4993 28 . . . cord-006870-f5w6fw6q 4994 1 The the DT cord-006870-f5w6fw6q 4994 2 proportion proportion NN cord-006870-f5w6fw6q 4994 3 of of IN cord-006870-f5w6fw6q 4994 4 patients patient NNS cord-006870-f5w6fw6q 4994 5 developing develop VBG cord-006870-f5w6fw6q 4994 6 AKI AKI NNP cord-006870-f5w6fw6q 4994 7 with with IN cord-006870-f5w6fw6q 4994 8 a a DT cord-006870-f5w6fw6q 4994 9 maximal maximal JJ cord-006870-f5w6fw6q 4994 10 serum serum NN cord-006870-f5w6fw6q 4994 11 chloride chloride NN cord-006870-f5w6fw6q 4994 12 concentration concentration NN cord-006870-f5w6fw6q 4994 13 of of IN cord-006870-f5w6fw6q 4994 14 108 108 CD cord-006870-f5w6fw6q 4994 15 ( ( -LRB- cord-006870-f5w6fw6q 4994 16 p p NN cord-006870-f5w6fw6q 4994 17 109 109 CD cord-006870-f5w6fw6q 4994 18 , , , cord-006870-f5w6fw6q 4994 19 will will MD cord-006870-f5w6fw6q 4994 20 be be VB cord-006870-f5w6fw6q 4994 21 randomized randomize VBN cord-006870-f5w6fw6q 4994 22 into into IN cord-006870-f5w6fw6q 4994 23 one one CD cord-006870-f5w6fw6q 4994 24 of of IN cord-006870-f5w6fw6q 4994 25 two two CD cord-006870-f5w6fw6q 4994 26 treatment treatment NN cord-006870-f5w6fw6q 4994 27 groups group NNS cord-006870-f5w6fw6q 4994 28 : : : cord-006870-f5w6fw6q 4994 29 standard standard JJ cord-006870-f5w6fw6q 4994 30 hypertonic hypertonic JJ cord-006870-f5w6fw6q 4994 31 saline saline NN cord-006870-f5w6fw6q 4994 32 solution solution NN cord-006870-f5w6fw6q 4994 33 ( ( -LRB- cord-006870-f5w6fw6q 4994 34 NaCl NaCl NNP cord-006870-f5w6fw6q 4994 35 23.4 23.4 CD cord-006870-f5w6fw6q 4994 36 % % NN cord-006870-f5w6fw6q 4994 37 ) ) -RRB- cord-006870-f5w6fw6q 4994 38 versus versus IN cord-006870-f5w6fw6q 4994 39 a a DT cord-006870-f5w6fw6q 4994 40 solution solution NN cord-006870-f5w6fw6q 4994 41 of of IN cord-006870-f5w6fw6q 4994 42 NaCl NaCl NNP cord-006870-f5w6fw6q 4994 43 / / SYM cord-006870-f5w6fw6q 4994 44 Na Na NNP cord-006870-f5w6fw6q 4994 45 - - HYPH cord-006870-f5w6fw6q 4994 46 Acetate Acetate NNP cord-006870-f5w6fw6q 4994 47 . . . cord-006870-f5w6fw6q 4995 1 We -PRON- PRP cord-006870-f5w6fw6q 4995 2 hypothesize hypothesize VBP cord-006870-f5w6fw6q 4995 3 that that IN cord-006870-f5w6fw6q 4995 4 by by IN cord-006870-f5w6fw6q 4995 5 reducing reduce VBG cord-006870-f5w6fw6q 4995 6 the the DT cord-006870-f5w6fw6q 4995 7 IV IV NNP cord-006870-f5w6fw6q 4995 8 chloride chloride NN cord-006870-f5w6fw6q 4995 9 burden(baseline burden(baseline NNP cord-006870-f5w6fw6q 4995 10 compared compare VBN cord-006870-f5w6fw6q 4995 11 to to IN cord-006870-f5w6fw6q 4995 12 post post VB cord-006870-f5w6fw6q 4995 13 randomization randomization NN cord-006870-f5w6fw6q 4995 14 exposure exposure NN cord-006870-f5w6fw6q 4995 15 ) ) -RRB- cord-006870-f5w6fw6q 4995 16 , , , cord-006870-f5w6fw6q 4995 17 the the DT cord-006870-f5w6fw6q 4995 18 delta delta NN cord-006870-f5w6fw6q 4995 19 serum serum NN cord-006870-f5w6fw6q 4995 20 chloride chloride NN cord-006870-f5w6fw6q 4995 21 level level NN cord-006870-f5w6fw6q 4995 22 will will MD cord-006870-f5w6fw6q 4995 23 decrease decrease VB cord-006870-f5w6fw6q 4995 24 , , , cord-006870-f5w6fw6q 4995 25 and and CC cord-006870-f5w6fw6q 4995 26 will will MD cord-006870-f5w6fw6q 4995 27 subsequently subsequently RB cord-006870-f5w6fw6q 4995 28 reduce reduce VB cord-006870-f5w6fw6q 4995 29 AKI AKI NNP cord-006870-f5w6fw6q 4995 30 occurrence occurrence NN cord-006870-f5w6fw6q 4995 31 ( ( -LRB- cord-006870-f5w6fw6q 4995 32 ACETATE acetate NN cord-006870-f5w6fw6q 4995 33 trial trial NN cord-006870-f5w6fw6q 4995 34 , , , cord-006870-f5w6fw6q 4995 35 clinicaltrials.gov clinicaltrials.gov NNP cord-006870-f5w6fw6q 4995 36 NCT03204955 NCT03204955 NNP cord-006870-f5w6fw6q 4995 37 ) ) -RRB- cord-006870-f5w6fw6q 4995 38 . . . cord-006870-f5w6fw6q 4996 1 AKI AKI NNP cord-006870-f5w6fw6q 4996 2 is be VBZ cord-006870-f5w6fw6q 4996 3 common common JJ cord-006870-f5w6fw6q 4996 4 in in IN cord-006870-f5w6fw6q 4996 5 SAH SAH NNP cord-006870-f5w6fw6q 4996 6 patient patient JJ cord-006870-f5w6fw6q 4996 7 population population NN cord-006870-f5w6fw6q 4996 8 , , , cord-006870-f5w6fw6q 4996 9 and and CC cord-006870-f5w6fw6q 4996 10 associated associate VBN cord-006870-f5w6fw6q 4996 11 with with IN cord-006870-f5w6fw6q 4996 12 worse bad JJR cord-006870-f5w6fw6q 4996 13 outcomes outcome NNS cord-006870-f5w6fw6q 4996 14 . . . cord-006870-f5w6fw6q 4997 1 Serum serum NN cord-006870-f5w6fw6q 4997 2 chloride chloride NN cord-006870-f5w6fw6q 4997 3 concentrations concentration NNS cord-006870-f5w6fw6q 4997 4 are be VBP cord-006870-f5w6fw6q 4997 5 a a DT cord-006870-f5w6fw6q 4997 6 significant significant JJ cord-006870-f5w6fw6q 4997 7 risk risk NN cord-006870-f5w6fw6q 4997 8 factor factor NN cord-006870-f5w6fw6q 4997 9 for for IN cord-006870-f5w6fw6q 4997 10 the the DT cord-006870-f5w6fw6q 4997 11 development development NN cord-006870-f5w6fw6q 4997 12 of of IN cord-006870-f5w6fw6q 4997 13 AKI AKI NNP cord-006870-f5w6fw6q 4997 14 . . . cord-006870-f5w6fw6q 4998 1 A a DT cord-006870-f5w6fw6q 4998 2 prospective prospective JJ cord-006870-f5w6fw6q 4998 3 randomized randomized JJ cord-006870-f5w6fw6q 4998 4 clinical clinical JJ cord-006870-f5w6fw6q 4998 5 trial trial NN cord-006870-f5w6fw6q 4998 6 now now RB cord-006870-f5w6fw6q 4998 7 underway underway RB cord-006870-f5w6fw6q 4998 8 examining examine VBG cord-006870-f5w6fw6q 4998 9 the the DT cord-006870-f5w6fw6q 4998 10 relationship relationship NN cord-006870-f5w6fw6q 4998 11 between between IN cord-006870-f5w6fw6q 4998 12 the the DT cord-006870-f5w6fw6q 4998 13 hypertonic hypertonic JJ cord-006870-f5w6fw6q 4998 14 solution solution NN cord-006870-f5w6fw6q 4998 15 composition composition NN cord-006870-f5w6fw6q 4998 16 and and CC cord-006870-f5w6fw6q 4998 17 serum serum NN cord-006870-f5w6fw6q 4998 18 chloride chloride NN cord-006870-f5w6fw6q 4998 19 concentration concentration NN cord-006870-f5w6fw6q 4998 20 , , , cord-006870-f5w6fw6q 4998 21 and and CC cord-006870-f5w6fw6q 4998 22 to to IN cord-006870-f5w6fw6q 4998 23 the the DT cord-006870-f5w6fw6q 4998 24 development development NN cord-006870-f5w6fw6q 4998 25 of of IN cord-006870-f5w6fw6q 4998 26 acute acute JJ cord-006870-f5w6fw6q 4998 27 kidney kidney NN cord-006870-f5w6fw6q 4998 28 injury injury NN cord-006870-f5w6fw6q 4998 29 in in IN cord-006870-f5w6fw6q 4998 30 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 4998 31 SAH SAH NNP cord-006870-f5w6fw6q 4998 32 . . . cord-006870-f5w6fw6q 4999 1 Spontaneous spontaneous JJ cord-006870-f5w6fw6q 4999 2 spinal spinal JJ cord-006870-f5w6fw6q 4999 3 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 4999 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 4999 5 ( ( -LRB- cord-006870-f5w6fw6q 4999 6 SSAH SSAH NNP cord-006870-f5w6fw6q 4999 7 ) ) -RRB- cord-006870-f5w6fw6q 4999 8 is be VBZ cord-006870-f5w6fw6q 4999 9 a a DT cord-006870-f5w6fw6q 4999 10 rare rare JJ cord-006870-f5w6fw6q 4999 11 but but CC cord-006870-f5w6fw6q 4999 12 serious serious JJ cord-006870-f5w6fw6q 4999 13 condition condition NN cord-006870-f5w6fw6q 4999 14 that that WDT cord-006870-f5w6fw6q 4999 15 can can MD cord-006870-f5w6fw6q 4999 16 lead lead VB cord-006870-f5w6fw6q 4999 17 to to IN cord-006870-f5w6fw6q 4999 18 a a DT cord-006870-f5w6fw6q 4999 19 variety variety NN cord-006870-f5w6fw6q 4999 20 of of IN cord-006870-f5w6fw6q 4999 21 medical medical JJ cord-006870-f5w6fw6q 4999 22 complications complication NNS cord-006870-f5w6fw6q 4999 23 . . . cord-006870-f5w6fw6q 5000 1 Literature literature NN cord-006870-f5w6fw6q 5000 2 to to IN cord-006870-f5w6fw6q 5000 3 this this DT cord-006870-f5w6fw6q 5000 4 point point NN cord-006870-f5w6fw6q 5000 5 primarily primarily RB cord-006870-f5w6fw6q 5000 6 includes include VBZ cord-006870-f5w6fw6q 5000 7 isolated isolate VBN cord-006870-f5w6fw6q 5000 8 case case NN cord-006870-f5w6fw6q 5000 9 reports report NNS cord-006870-f5w6fw6q 5000 10 , , , cord-006870-f5w6fw6q 5000 11 and and CC cord-006870-f5w6fw6q 5000 12 none none NN cord-006870-f5w6fw6q 5000 13 have have VBP cord-006870-f5w6fw6q 5000 14 looked look VBN cord-006870-f5w6fw6q 5000 15 at at IN cord-006870-f5w6fw6q 5000 16 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 5000 17 as as IN cord-006870-f5w6fw6q 5000 18 a a DT cord-006870-f5w6fw6q 5000 19 complication complication NN cord-006870-f5w6fw6q 5000 20 . . . cord-006870-f5w6fw6q 5001 1 Patients patient NNS cord-006870-f5w6fw6q 5001 2 were be VBD cord-006870-f5w6fw6q 5001 3 identified identify VBN cord-006870-f5w6fw6q 5001 4 from from IN cord-006870-f5w6fw6q 5001 5 the the DT cord-006870-f5w6fw6q 5001 6 electronic electronic JJ cord-006870-f5w6fw6q 5001 7 medical medical JJ cord-006870-f5w6fw6q 5001 8 record record NN cord-006870-f5w6fw6q 5001 9 database database NN cord-006870-f5w6fw6q 5001 10 at at IN cord-006870-f5w6fw6q 5001 11 the the DT cord-006870-f5w6fw6q 5001 12 Mayo Mayo NNP cord-006870-f5w6fw6q 5001 13 Clinic Clinic NNP cord-006870-f5w6fw6q 5001 14 in in IN cord-006870-f5w6fw6q 5001 15 Rochester Rochester NNP cord-006870-f5w6fw6q 5001 16 , , , cord-006870-f5w6fw6q 5001 17 Minnesota Minnesota NNP cord-006870-f5w6fw6q 5001 18 . . . cord-006870-f5w6fw6q 5002 1 The the DT cord-006870-f5w6fw6q 5002 2 Advanced Advanced NNP cord-006870-f5w6fw6q 5002 3 Cohort Cohort NNP cord-006870-f5w6fw6q 5002 4 Explorer Explorer NNP cord-006870-f5w6fw6q 5002 5 tool tool NN cord-006870-f5w6fw6q 5002 6 was be VBD cord-006870-f5w6fw6q 5002 7 used use VBN cord-006870-f5w6fw6q 5002 8 , , , cord-006870-f5w6fw6q 5002 9 searching search VBG cord-006870-f5w6fw6q 5002 10 from from IN cord-006870-f5w6fw6q 5002 11 January January NNP cord-006870-f5w6fw6q 5002 12 2000 2000 CD cord-006870-f5w6fw6q 5002 13 to to IN cord-006870-f5w6fw6q 5002 14 December December NNP cord-006870-f5w6fw6q 5002 15 2015 2015 CD cord-006870-f5w6fw6q 5002 16 . . . cord-006870-f5w6fw6q 5003 1 Inclusion inclusion NN cord-006870-f5w6fw6q 5003 2 criteria criterion NNS cord-006870-f5w6fw6q 5003 3 were be VBD cord-006870-f5w6fw6q 5003 4 spinal spinal JJ cord-006870-f5w6fw6q 5003 5 subarachnoid subarachnoid JJ cord-006870-f5w6fw6q 5003 6 blood blood NN cord-006870-f5w6fw6q 5003 7 products product NNS cord-006870-f5w6fw6q 5003 8 due due JJ cord-006870-f5w6fw6q 5003 9 to to IN cord-006870-f5w6fw6q 5003 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5003 11 into into IN cord-006870-f5w6fw6q 5003 12 the the DT cord-006870-f5w6fw6q 5003 13 spinal spinal JJ cord-006870-f5w6fw6q 5003 14 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5003 15 space space NN cord-006870-f5w6fw6q 5003 16 not not RB cord-006870-f5w6fw6q 5003 17 due due JJ cord-006870-f5w6fw6q 5003 18 to to IN cord-006870-f5w6fw6q 5003 19 ( ( -LRB- cord-006870-f5w6fw6q 5003 20 1 1 CD cord-006870-f5w6fw6q 5003 21 ) ) -RRB- cord-006870-f5w6fw6q 5003 22 redistribution redistribution NN cord-006870-f5w6fw6q 5003 23 of of IN cord-006870-f5w6fw6q 5003 24 blood blood NN cord-006870-f5w6fw6q 5003 25 from from IN cord-006870-f5w6fw6q 5003 26 intracranial intracranial JJ cord-006870-f5w6fw6q 5003 27 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5003 28 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5003 29 , , , cord-006870-f5w6fw6q 5003 30 ( ( -LRB- cord-006870-f5w6fw6q 5003 31 2 2 LS cord-006870-f5w6fw6q 5003 32 ) ) -RRB- cord-006870-f5w6fw6q 5003 33 trauma trauma NN cord-006870-f5w6fw6q 5003 34 , , , cord-006870-f5w6fw6q 5003 35 ( ( -LRB- cord-006870-f5w6fw6q 5003 36 3 3 LS cord-006870-f5w6fw6q 5003 37 ) ) -RRB- cord-006870-f5w6fw6q 5003 38 medical medical JJ cord-006870-f5w6fw6q 5003 39 procedures procedure NNS cord-006870-f5w6fw6q 5003 40 , , , cord-006870-f5w6fw6q 5003 41 or or CC cord-006870-f5w6fw6q 5003 42 4 4 CD cord-006870-f5w6fw6q 5003 43 ) ) -RRB- cord-006870-f5w6fw6q 5003 44 predominant predominant JJ cord-006870-f5w6fw6q 5003 45 hematomyelia hematomyelia NNP cord-006870-f5w6fw6q 5003 46 who who WP cord-006870-f5w6fw6q 5003 47 experienced experience VBD cord-006870-f5w6fw6q 5003 48 symptoms symptom NNS cord-006870-f5w6fw6q 5003 49 and and CC cord-006870-f5w6fw6q 5003 50 received receive VBD cord-006870-f5w6fw6q 5003 51 treatment treatment NN cord-006870-f5w6fw6q 5003 52 at at IN cord-006870-f5w6fw6q 5003 53 our -PRON- PRP$ cord-006870-f5w6fw6q 5003 54 facility facility NN cord-006870-f5w6fw6q 5003 55 . . . cord-006870-f5w6fw6q 5004 1 Eight eight CD cord-006870-f5w6fw6q 5004 2 patients patient NNS cord-006870-f5w6fw6q 5004 3 ( ( -LRB- cord-006870-f5w6fw6q 5004 4 median median JJ cord-006870-f5w6fw6q 5004 5 age age NN cord-006870-f5w6fw6q 5004 6 70 70 CD cord-006870-f5w6fw6q 5004 7 years year NNS cord-006870-f5w6fw6q 5004 8 , , , cord-006870-f5w6fw6q 5004 9 range range VBP cord-006870-f5w6fw6q 5004 10 51 51 CD cord-006870-f5w6fw6q 5004 11 - - SYM cord-006870-f5w6fw6q 5004 12 87 87 CD cord-006870-f5w6fw6q 5004 13 ) ) -RRB- cord-006870-f5w6fw6q 5004 14 were be VBD cord-006870-f5w6fw6q 5004 15 identified identify VBN cord-006870-f5w6fw6q 5004 16 as as IN cord-006870-f5w6fw6q 5004 17 meeting meet VBG cord-006870-f5w6fw6q 5004 18 the the DT cord-006870-f5w6fw6q 5004 19 study study NN cord-006870-f5w6fw6q 5004 20 criteria criterion NNS cord-006870-f5w6fw6q 5004 21 . . . cord-006870-f5w6fw6q 5005 1 Five five CD cord-006870-f5w6fw6q 5005 2 of of IN cord-006870-f5w6fw6q 5005 3 these these DT cord-006870-f5w6fw6q 5005 4 eight eight CD cord-006870-f5w6fw6q 5005 5 patients patient NNS cord-006870-f5w6fw6q 5005 6 experienced experience VBD cord-006870-f5w6fw6q 5005 7 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 5005 8 during during IN cord-006870-f5w6fw6q 5005 9 hospitalization hospitalization NN cord-006870-f5w6fw6q 5005 10 with with IN cord-006870-f5w6fw6q 5005 11 a a DT cord-006870-f5w6fw6q 5005 12 median median JJ cord-006870-f5w6fw6q 5005 13 value value NN cord-006870-f5w6fw6q 5005 14 of of IN cord-006870-f5w6fw6q 5005 15 125 125 CD cord-006870-f5w6fw6q 5005 16 meq meq NNP cord-006870-f5w6fw6q 5005 17 / / SYM cord-006870-f5w6fw6q 5005 18 L. L. NNP cord-006870-f5w6fw6q 5006 1 All all DT cord-006870-f5w6fw6q 5006 2 of of IN cord-006870-f5w6fw6q 5006 3 these these DT cord-006870-f5w6fw6q 5006 4 patients patient NNS cord-006870-f5w6fw6q 5006 5 were be VBD cord-006870-f5w6fw6q 5006 6 treated treat VBN cord-006870-f5w6fw6q 5006 7 with with IN cord-006870-f5w6fw6q 5006 8 free free JJ cord-006870-f5w6fw6q 5006 9 water water NN cord-006870-f5w6fw6q 5006 10 restriction restriction NN cord-006870-f5w6fw6q 5006 11 and and CC cord-006870-f5w6fw6q 5006 12 one one CD cord-006870-f5w6fw6q 5006 13 patient patient NN cord-006870-f5w6fw6q 5006 14 briefly briefly RB cord-006870-f5w6fw6q 5006 15 received receive VBD cord-006870-f5w6fw6q 5006 16 1.5 1.5 CD cord-006870-f5w6fw6q 5006 17 % % NN cord-006870-f5w6fw6q 5006 18 sodium sodium NN cord-006870-f5w6fw6q 5006 19 chloride chloride NN cord-006870-f5w6fw6q 5006 20 solution solution NN cord-006870-f5w6fw6q 5006 21 ; ; : cord-006870-f5w6fw6q 5006 22 in in IN cord-006870-f5w6fw6q 5006 23 all all DT cord-006870-f5w6fw6q 5006 24 cases case NNS cord-006870-f5w6fw6q 5006 25 the the DT cord-006870-f5w6fw6q 5006 26 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 5006 27 improved improve VBD cord-006870-f5w6fw6q 5006 28 after after IN cord-006870-f5w6fw6q 5006 29 free free JJ cord-006870-f5w6fw6q 5006 30 water water NN cord-006870-f5w6fw6q 5006 31 restriction restriction NN cord-006870-f5w6fw6q 5006 32 . . . cord-006870-f5w6fw6q 5007 1 In in IN cord-006870-f5w6fw6q 5007 2 all all DT cord-006870-f5w6fw6q 5007 3 cases case NNS cord-006870-f5w6fw6q 5007 4 the the DT cord-006870-f5w6fw6q 5007 5 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 5007 6 improved improve VBD cord-006870-f5w6fw6q 5007 7 with with IN cord-006870-f5w6fw6q 5007 8 fluid fluid JJ cord-006870-f5w6fw6q 5007 9 restriction restriction NN cord-006870-f5w6fw6q 5007 10 , , , cord-006870-f5w6fw6q 5007 11 and and CC cord-006870-f5w6fw6q 5007 12 there there EX cord-006870-f5w6fw6q 5007 13 was be VBD cord-006870-f5w6fw6q 5007 14 no no DT cord-006870-f5w6fw6q 5007 15 documentation documentation NN cord-006870-f5w6fw6q 5007 16 of of IN cord-006870-f5w6fw6q 5007 17 increased increase VBN cord-006870-f5w6fw6q 5007 18 urine urine NN cord-006870-f5w6fw6q 5007 19 output output NN cord-006870-f5w6fw6q 5007 20 , , , cord-006870-f5w6fw6q 5007 21 suggesting suggest VBG cord-006870-f5w6fw6q 5007 22 that that IN cord-006870-f5w6fw6q 5007 23 it -PRON- PRP cord-006870-f5w6fw6q 5007 24 was be VBD cord-006870-f5w6fw6q 5007 25 likely likely JJ cord-006870-f5w6fw6q 5007 26 due due IN cord-006870-f5w6fw6q 5007 27 to to IN cord-006870-f5w6fw6q 5007 28 SIADH SIADH NNP cord-006870-f5w6fw6q 5007 29 . . . cord-006870-f5w6fw6q 5008 1 Cord cord NN cord-006870-f5w6fw6q 5008 2 compression compression NN cord-006870-f5w6fw6q 5008 3 and and CC cord-006870-f5w6fw6q 5008 4 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 5008 5 were be VBD cord-006870-f5w6fw6q 5008 6 present present JJ cord-006870-f5w6fw6q 5008 7 together together RB cord-006870-f5w6fw6q 5008 8 in in IN cord-006870-f5w6fw6q 5008 9 two two CD cord-006870-f5w6fw6q 5008 10 patients patient NNS cord-006870-f5w6fw6q 5008 11 , , , cord-006870-f5w6fw6q 5008 12 and and CC cord-006870-f5w6fw6q 5008 13 in in IN cord-006870-f5w6fw6q 5008 14 these these DT cord-006870-f5w6fw6q 5008 15 cases case NNS cord-006870-f5w6fw6q 5008 16 treatment treatment NN cord-006870-f5w6fw6q 5008 17 of of IN cord-006870-f5w6fw6q 5008 18 the the DT cord-006870-f5w6fw6q 5008 19 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 5008 20 was be VBD cord-006870-f5w6fw6q 5008 21 particularly particularly RB cord-006870-f5w6fw6q 5008 22 useful useful JJ cord-006870-f5w6fw6q 5008 23 to to TO cord-006870-f5w6fw6q 5008 24 avoid avoid VB cord-006870-f5w6fw6q 5008 25 worsening worsen VBG cord-006870-f5w6fw6q 5008 26 edema edema NN cord-006870-f5w6fw6q 5008 27 . . . cord-006870-f5w6fw6q 5009 1 To to IN cord-006870-f5w6fw6q 5009 2 our -PRON- PRP$ cord-006870-f5w6fw6q 5009 3 knowledge knowledge NN cord-006870-f5w6fw6q 5009 4 this this DT cord-006870-f5w6fw6q 5009 5 is be VBZ cord-006870-f5w6fw6q 5009 6 the the DT cord-006870-f5w6fw6q 5009 7 first first JJ cord-006870-f5w6fw6q 5009 8 compilation compilation NN cord-006870-f5w6fw6q 5009 9 of of IN cord-006870-f5w6fw6q 5009 10 cases case NNS cord-006870-f5w6fw6q 5009 11 of of IN cord-006870-f5w6fw6q 5009 12 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5009 13 SSAH SSAH NNP cord-006870-f5w6fw6q 5009 14 highlighting highlight VBG cord-006870-f5w6fw6q 5009 15 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 5009 16 as as IN cord-006870-f5w6fw6q 5009 17 a a DT cord-006870-f5w6fw6q 5009 18 complication complication NN cord-006870-f5w6fw6q 5009 19 . . . cord-006870-f5w6fw6q 5010 1 There there EX cord-006870-f5w6fw6q 5010 2 is be VBZ cord-006870-f5w6fw6q 5010 3 significant significant JJ cord-006870-f5w6fw6q 5010 4 morbidity morbidity NN cord-006870-f5w6fw6q 5010 5 and and CC cord-006870-f5w6fw6q 5010 6 mortality mortality NN cord-006870-f5w6fw6q 5010 7 associated associate VBN cord-006870-f5w6fw6q 5010 8 with with IN cord-006870-f5w6fw6q 5010 9 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 5010 10 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5010 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5010 12 ( ( -LRB- cord-006870-f5w6fw6q 5010 13 SAH SAH NNP cord-006870-f5w6fw6q 5010 14 ) ) -RRB- cord-006870-f5w6fw6q 5010 15 and and CC cord-006870-f5w6fw6q 5010 16 only only RB cord-006870-f5w6fw6q 5010 17 about about RB cord-006870-f5w6fw6q 5010 18 20 20 CD cord-006870-f5w6fw6q 5010 19 % % NN cord-006870-f5w6fw6q 5010 20 of of IN cord-006870-f5w6fw6q 5010 21 patients patient NNS cord-006870-f5w6fw6q 5010 22 survive survive VBP cord-006870-f5w6fw6q 5010 23 and and CC cord-006870-f5w6fw6q 5010 24 resume resume VB cord-006870-f5w6fw6q 5010 25 their -PRON- PRP$ cord-006870-f5w6fw6q 5010 26 previous previous JJ cord-006870-f5w6fw6q 5010 27 lifestyle lifestyle NN cord-006870-f5w6fw6q 5010 28 after after IN cord-006870-f5w6fw6q 5010 29 3 3 CD cord-006870-f5w6fw6q 5010 30 - - SYM cord-006870-f5w6fw6q 5010 31 6 6 CD cord-006870-f5w6fw6q 5010 32 months month NNS cord-006870-f5w6fw6q 5010 33 . . . cord-006870-f5w6fw6q 5011 1 Many many JJ cord-006870-f5w6fw6q 5011 2 randomized randomized JJ cord-006870-f5w6fw6q 5011 3 clinical clinical JJ cord-006870-f5w6fw6q 5011 4 trials trial NNS cord-006870-f5w6fw6q 5011 5 ( ( -LRB- cord-006870-f5w6fw6q 5011 6 RCTs RCTs NNP cord-006870-f5w6fw6q 5011 7 ) ) -RRB- cord-006870-f5w6fw6q 5011 8 have have VBP cord-006870-f5w6fw6q 5011 9 been be VBN cord-006870-f5w6fw6q 5011 10 conducted conduct VBN cord-006870-f5w6fw6q 5011 11 yet yet RB cord-006870-f5w6fw6q 5011 12 no no DT cord-006870-f5w6fw6q 5011 13 treatment treatment NN cord-006870-f5w6fw6q 5011 14 definitively definitively RB cord-006870-f5w6fw6q 5011 15 improves improve VBZ cord-006870-f5w6fw6q 5011 16 outcome outcome NN cord-006870-f5w6fw6q 5011 17 from from IN cord-006870-f5w6fw6q 5011 18 SAH SAH NNP cord-006870-f5w6fw6q 5011 19 . . . cord-006870-f5w6fw6q 5012 1 Outcome outcome NN cord-006870-f5w6fw6q 5012 2 is be VBZ cord-006870-f5w6fw6q 5012 3 strongly strongly RB cord-006870-f5w6fw6q 5012 4 related relate VBN cord-006870-f5w6fw6q 5012 5 to to IN cord-006870-f5w6fw6q 5012 6 baseline baseline JJ cord-006870-f5w6fw6q 5012 7 factors factor NNS cord-006870-f5w6fw6q 5012 8 , , , cord-006870-f5w6fw6q 5012 9 yet yet CC cord-006870-f5w6fw6q 5012 10 imbalances imbalance NNS cord-006870-f5w6fw6q 5012 11 are be VBP cord-006870-f5w6fw6q 5012 12 common common JJ cord-006870-f5w6fw6q 5012 13 in in IN cord-006870-f5w6fw6q 5012 14 early early JJ cord-006870-f5w6fw6q 5012 15 trials trial NNS cord-006870-f5w6fw6q 5012 16 . . . cord-006870-f5w6fw6q 5013 1 We -PRON- PRP cord-006870-f5w6fw6q 5013 2 developed develop VBD cord-006870-f5w6fw6q 5013 3 a a DT cord-006870-f5w6fw6q 5013 4 technique technique NN cord-006870-f5w6fw6q 5013 5 to to TO cord-006870-f5w6fw6q 5013 6 identify identify VB cord-006870-f5w6fw6q 5013 7 promising promising JJ cord-006870-f5w6fw6q 5013 8 treatments treatment NNS cord-006870-f5w6fw6q 5013 9 at at IN cord-006870-f5w6fw6q 5013 10 early early JJ cord-006870-f5w6fw6q 5013 11 phase phase NN cord-006870-f5w6fw6q 5013 12 using use VBG cord-006870-f5w6fw6q 5013 13 a a DT cord-006870-f5w6fw6q 5013 14 pooled pool VBN cord-006870-f5w6fw6q 5013 15 control control NN cord-006870-f5w6fw6q 5013 16 arm arm NN cord-006870-f5w6fw6q 5013 17 model model NN cord-006870-f5w6fw6q 5013 18 ( ( -LRB- cord-006870-f5w6fw6q 5013 19 pPREDICTS ppredicts NN cord-006870-f5w6fw6q 5013 20 : : : cord-006870-f5w6fw6q 5014 1 Kent Kent NNP cord-006870-f5w6fw6q 5014 2 , , , cord-006870-f5w6fw6q 5014 3 Shah Shah NNP cord-006870-f5w6fw6q 5014 4 , , , cord-006870-f5w6fw6q 5014 5 Mandava Mandava NNP cord-006870-f5w6fw6q 5014 6 Neurology Neurology NNP cord-006870-f5w6fw6q 5014 7 2015 2015 CD cord-006870-f5w6fw6q 5014 8 ) ) -RRB- cord-006870-f5w6fw6q 5014 9 that that WDT cord-006870-f5w6fw6q 5014 10 compares compare VBZ cord-006870-f5w6fw6q 5014 11 early early JJ cord-006870-f5w6fw6q 5014 12 studies study NNS cord-006870-f5w6fw6q 5014 13 at at IN cord-006870-f5w6fw6q 5014 14 their -PRON- PRP$ cord-006870-f5w6fw6q 5014 15 own own JJ cord-006870-f5w6fw6q 5014 16 baselines baseline NNS cord-006870-f5w6fw6q 5014 17 . . . cord-006870-f5w6fw6q 5015 1 We -PRON- PRP cord-006870-f5w6fw6q 5015 2 applied apply VBD cord-006870-f5w6fw6q 5015 3 this this DT cord-006870-f5w6fw6q 5015 4 method method NN cord-006870-f5w6fw6q 5015 5 to to IN cord-006870-f5w6fw6q 5015 6 SAH SAH NNP cord-006870-f5w6fw6q 5015 7 to to TO cord-006870-f5w6fw6q 5015 8 develop develop VB cord-006870-f5w6fw6q 5015 9 a a DT cord-006870-f5w6fw6q 5015 10 multi multi JJ cord-006870-f5w6fw6q 5015 11 - - JJ cord-006870-f5w6fw6q 5015 12 dimensional dimensional JJ cord-006870-f5w6fw6q 5015 13 model model NN cord-006870-f5w6fw6q 5015 14 ( ( -LRB- cord-006870-f5w6fw6q 5015 15 pPREDICTS ppredicts JJ cord-006870-f5w6fw6q 5015 16 - - HYPH cord-006870-f5w6fw6q 5015 17 SAH SAH NNP cord-006870-f5w6fw6q 5015 18 ) ) -RRB- cord-006870-f5w6fw6q 5015 19 . . . cord-006870-f5w6fw6q 5016 1 Models model NNS cord-006870-f5w6fw6q 5016 2 for for IN cord-006870-f5w6fw6q 5016 3 functional functional JJ cord-006870-f5w6fw6q 5016 4 outcome outcome NN cord-006870-f5w6fw6q 5016 5 and and CC cord-006870-f5w6fw6q 5016 6 mortality mortality NN cord-006870-f5w6fw6q 5016 7 ( ( -LRB- cord-006870-f5w6fw6q 5016 8 dependent dependent JJ cord-006870-f5w6fw6q 5016 9 variables variable NNS cord-006870-f5w6fw6q 5016 10 ) ) -RRB- cord-006870-f5w6fw6q 5016 11 were be VBD cord-006870-f5w6fw6q 5016 12 developed develop VBN cord-006870-f5w6fw6q 5016 13 based base VBN cord-006870-f5w6fw6q 5016 14 on on IN cord-006870-f5w6fw6q 5016 15 baseline baseline JJ cord-006870-f5w6fw6q 5016 16 variables variable NNS cord-006870-f5w6fw6q 5016 17 ( ( -LRB- cord-006870-f5w6fw6q 5016 18 eg eg IN cord-006870-f5w6fw6q 5016 19 : : : cord-006870-f5w6fw6q 5016 20 WFNS wfns NN cord-006870-f5w6fw6q 5016 21 grade grade NN cord-006870-f5w6fw6q 5016 22 4 4 CD cord-006870-f5w6fw6q 5016 23 - - SYM cord-006870-f5w6fw6q 5016 24 5 5 CD cord-006870-f5w6fw6q 5016 25 % % NN cord-006870-f5w6fw6q 5016 26 and and CC cord-006870-f5w6fw6q 5016 27 age age NN cord-006870-f5w6fw6q 5016 28 ) ) -RRB- cord-006870-f5w6fw6q 5016 29 using use VBG cord-006870-f5w6fw6q 5016 30 methodology methodology NN cord-006870-f5w6fw6q 5016 31 developed develop VBN cord-006870-f5w6fw6q 5016 32 for for IN cord-006870-f5w6fw6q 5016 33 ischemic ischemic JJ cord-006870-f5w6fw6q 5016 34 stroke stroke NN cord-006870-f5w6fw6q 5016 35 ( ( -LRB- cord-006870-f5w6fw6q 5016 36 Mandava Mandava NNP cord-006870-f5w6fw6q 5016 37 , , , cord-006870-f5w6fw6q 5016 38 Kent Kent NNP cord-006870-f5w6fw6q 5016 39 , , , cord-006870-f5w6fw6q 5016 40 Stroke Stroke NNP cord-006870-f5w6fw6q 5016 41 2009 2009 CD cord-006870-f5w6fw6q 5016 42 ) ) -RRB- cord-006870-f5w6fw6q 5016 43 . . . cord-006870-f5w6fw6q 5017 1 The the DT cord-006870-f5w6fw6q 5017 2 outcome outcome NN cord-006870-f5w6fw6q 5017 3 model model NN cord-006870-f5w6fw6q 5017 4 is be VBZ cord-006870-f5w6fw6q 5017 5 a a DT cord-006870-f5w6fw6q 5017 6 3-dimensional 3-dimensional CD cord-006870-f5w6fw6q 5017 7 surface surface NN cord-006870-f5w6fw6q 5017 8 bounded bound VBN cord-006870-f5w6fw6q 5017 9 on on IN cord-006870-f5w6fw6q 5017 10 either either DT cord-006870-f5w6fw6q 5017 11 side side NN cord-006870-f5w6fw6q 5017 12 by by IN cord-006870-f5w6fw6q 5017 13 + + CC cord-006870-f5w6fw6q 5017 14 /-0.1 /-0.1 . cord-006870-f5w6fw6q 5017 15 prediction prediction NN cord-006870-f5w6fw6q 5017 16 interval interval NN cord-006870-f5w6fw6q 5017 17 surfaces surface NNS cord-006870-f5w6fw6q 5017 18 . . . cord-006870-f5w6fw6q 5018 1 These these DT cord-006870-f5w6fw6q 5018 2 prediction prediction NN cord-006870-f5w6fw6q 5018 3 interval interval NN cord-006870-f5w6fw6q 5018 4 surfaces surface NNS cord-006870-f5w6fw6q 5018 5 incorporate incorporate VBP cord-006870-f5w6fw6q 5018 6 statistical statistical JJ cord-006870-f5w6fw6q 5018 7 variability variability NN cord-006870-f5w6fw6q 5018 8 to to TO cord-006870-f5w6fw6q 5018 9 assess assess VB cord-006870-f5w6fw6q 5018 10 whether whether IN cord-006870-f5w6fw6q 5018 11 a a DT cord-006870-f5w6fw6q 5018 12 treatment treatment NN cord-006870-f5w6fw6q 5018 13 differs differ VBZ cord-006870-f5w6fw6q 5018 14 from from IN cord-006870-f5w6fw6q 5018 15 expected expect VBN cord-006870-f5w6fw6q 5018 16 outcome outcome NN cord-006870-f5w6fw6q 5018 17 . . . cord-006870-f5w6fw6q 5019 1 Treatment treatment NN cord-006870-f5w6fw6q 5019 2 arms arm NNS cord-006870-f5w6fw6q 5019 3 from from IN cord-006870-f5w6fw6q 5019 4 RCTs rct NNS cord-006870-f5w6fw6q 5019 5 and and CC cord-006870-f5w6fw6q 5019 6 single single JJ cord-006870-f5w6fw6q 5019 7 arm arm NN cord-006870-f5w6fw6q 5019 8 trials trial NNS cord-006870-f5w6fw6q 5019 9 , , , cord-006870-f5w6fw6q 5019 10 of of IN cord-006870-f5w6fw6q 5019 11 various various JJ cord-006870-f5w6fw6q 5019 12 treatments treatment NNS cord-006870-f5w6fw6q 5019 13 of of IN cord-006870-f5w6fw6q 5019 14 SAH SAH NNP cord-006870-f5w6fw6q 5019 15 were be VBD cord-006870-f5w6fw6q 5019 16 compared compare VBN cord-006870-f5w6fw6q 5019 17 against against IN cord-006870-f5w6fw6q 5019 18 the the DT cord-006870-f5w6fw6q 5019 19 pooled pool VBN cord-006870-f5w6fw6q 5019 20 controlled controlled JJ cord-006870-f5w6fw6q 5019 21 arm arm NN cord-006870-f5w6fw6q 5019 22 . . . cord-006870-f5w6fw6q 5020 1 The the DT cord-006870-f5w6fw6q 5020 2 best good JJS cord-006870-f5w6fw6q 5020 3 model model NN cord-006870-f5w6fw6q 5020 4 fit fit NN cord-006870-f5w6fw6q 5020 5 was be VBD cord-006870-f5w6fw6q 5020 6 for for IN cord-006870-f5w6fw6q 5020 7 good good JJ cord-006870-f5w6fw6q 5020 8 outcome outcome NN cord-006870-f5w6fw6q 5020 9 ( ( -LRB- cord-006870-f5w6fw6q 5020 10 modified modify VBN cord-006870-f5w6fw6q 5020 11 Rankin Rankin NNP cord-006870-f5w6fw6q 5020 12 Score Score NNP cord-006870-f5w6fw6q 5020 13 0 0 CD cord-006870-f5w6fw6q 5020 14 - - SYM cord-006870-f5w6fw6q 5020 15 2 2 CD cord-006870-f5w6fw6q 5020 16 equivalents equivalent NNS cord-006870-f5w6fw6q 5020 17 ) ) -RRB- cord-006870-f5w6fw6q 5020 18 based base VBN cord-006870-f5w6fw6q 5020 19 on on IN cord-006870-f5w6fw6q 5020 20 % % NN cord-006870-f5w6fw6q 5020 21 patients patient NNS cord-006870-f5w6fw6q 5020 22 with with IN cord-006870-f5w6fw6q 5020 23 WFNS WFNS NNP cord-006870-f5w6fw6q 5020 24 4 4 CD cord-006870-f5w6fw6q 5020 25 - - SYM cord-006870-f5w6fw6q 5020 26 5 5 CD cord-006870-f5w6fw6q 5020 27 and and CC cord-006870-f5w6fw6q 5020 28 age age NN cord-006870-f5w6fw6q 5021 1 ( ( -LRB- cord-006870-f5w6fw6q 5021 2 R2=0.54 R2=0.54 NNP cord-006870-f5w6fw6q 5021 3 ; ; : cord-006870-f5w6fw6q 5021 4 p<0.001 p<0.001 CD cord-006870-f5w6fw6q 5021 5 ) ) -RRB- cord-006870-f5w6fw6q 5021 6 . . . cord-006870-f5w6fw6q 5022 1 Seven seven CD cord-006870-f5w6fw6q 5022 2 trials trial NNS cord-006870-f5w6fw6q 5022 3 of of IN cord-006870-f5w6fw6q 5022 4 known know VBN cord-006870-f5w6fw6q 5022 5 negative negative JJ cord-006870-f5w6fw6q 5022 6 drug drug NN cord-006870-f5w6fw6q 5022 7 tirilazad tirilazad NNP cord-006870-f5w6fw6q 5022 8 were be VBD cord-006870-f5w6fw6q 5022 9 superimposed superimpose VBN cord-006870-f5w6fw6q 5022 10 on on IN cord-006870-f5w6fw6q 5022 11 the the DT cord-006870-f5w6fw6q 5022 12 model model NN cord-006870-f5w6fw6q 5022 13 and and CC cord-006870-f5w6fw6q 5022 14 fall fall VB cord-006870-f5w6fw6q 5022 15 within within IN cord-006870-f5w6fw6q 5022 16 the the DT cord-006870-f5w6fw6q 5022 17 + + NN cord-006870-f5w6fw6q 5022 18 /-0.1 /-0.1 . cord-006870-f5w6fw6q 5022 19 prediction prediction NN cord-006870-f5w6fw6q 5022 20 interval interval NN cord-006870-f5w6fw6q 5022 21 surfaces surface NNS cord-006870-f5w6fw6q 5022 22 confirming confirm VBG cord-006870-f5w6fw6q 5022 23 futility futility NN cord-006870-f5w6fw6q 5022 24 . . . cord-006870-f5w6fw6q 5023 1 Three three CD cord-006870-f5w6fw6q 5023 2 trials trial NNS cord-006870-f5w6fw6q 5023 3 were be VBD cord-006870-f5w6fw6q 5023 4 neutral neutral JJ cord-006870-f5w6fw6q 5023 5 and and CC cord-006870-f5w6fw6q 5023 6 within within IN cord-006870-f5w6fw6q 5023 7 the the DT cord-006870-f5w6fw6q 5023 8 prediction prediction NN cord-006870-f5w6fw6q 5023 9 interval interval NN cord-006870-f5w6fw6q 5023 10 surfaces surface NNS cord-006870-f5w6fw6q 5023 11 while while IN cord-006870-f5w6fw6q 5023 12 case case NN cord-006870-f5w6fw6q 5023 13 series series NN cord-006870-f5w6fw6q 5023 14 using use VBG cord-006870-f5w6fw6q 5023 15 implanted implant VBN cord-006870-f5w6fw6q 5023 16 prolonged prolonged JJ cord-006870-f5w6fw6q 5023 17 release release NN cord-006870-f5w6fw6q 5023 18 nicardipine nicardipine NN cord-006870-f5w6fw6q 5023 19 and and CC cord-006870-f5w6fw6q 5023 20 a a DT cord-006870-f5w6fw6q 5023 21 low low JJ cord-006870-f5w6fw6q 5023 22 dose dose NN cord-006870-f5w6fw6q 5023 23 heparin heparin NN cord-006870-f5w6fw6q 5023 24 study study NN cord-006870-f5w6fw6q 5023 25 were be VBD cord-006870-f5w6fw6q 5023 26 above above IN cord-006870-f5w6fw6q 5023 27 the the DT cord-006870-f5w6fw6q 5023 28 + + NN cord-006870-f5w6fw6q 5024 1 p=0.1 p=0.1 NN cord-006870-f5w6fw6q 5024 2 surface surface NN cord-006870-f5w6fw6q 5024 3 showing show VBG cord-006870-f5w6fw6q 5024 4 promise promise NN cord-006870-f5w6fw6q 5024 5 . . . cord-006870-f5w6fw6q 5025 1 Models model NNS cord-006870-f5w6fw6q 5025 2 were be VBD cord-006870-f5w6fw6q 5025 3 also also RB cord-006870-f5w6fw6q 5025 4 developed develop VBN cord-006870-f5w6fw6q 5025 5 for for IN cord-006870-f5w6fw6q 5025 6 mortality mortality NN cord-006870-f5w6fw6q 5025 7 ( ( -LRB- cord-006870-f5w6fw6q 5025 8 R2=0.23 R2=0.23 NNP cord-006870-f5w6fw6q 5025 9 , , , cord-006870-f5w6fw6q 5025 10 p=.02 p=.02 NNP cord-006870-f5w6fw6q 5025 11 ) ) -RRB- cord-006870-f5w6fw6q 5025 12 . . . cord-006870-f5w6fw6q 5026 1 Outcome outcome NN cord-006870-f5w6fw6q 5026 2 models model NNS cord-006870-f5w6fw6q 5026 3 based base VBN cord-006870-f5w6fw6q 5026 4 on on IN cord-006870-f5w6fw6q 5026 5 percentage percentage NN cord-006870-f5w6fw6q 5026 6 of of IN cord-006870-f5w6fw6q 5026 7 high high JJ cord-006870-f5w6fw6q 5026 8 grade grade NN cord-006870-f5w6fw6q 5026 9 WFNS wfns NN cord-006870-f5w6fw6q 5026 10 and and CC cord-006870-f5w6fw6q 5026 11 age age NN cord-006870-f5w6fw6q 5026 12 were be VBD cord-006870-f5w6fw6q 5026 13 successfully successfully RB cord-006870-f5w6fw6q 5026 14 developed develop VBN cord-006870-f5w6fw6q 5026 15 . . . cord-006870-f5w6fw6q 5027 1 This this DT cord-006870-f5w6fw6q 5027 2 approach approach NN cord-006870-f5w6fw6q 5027 3 may may MD cord-006870-f5w6fw6q 5027 4 be be VB cord-006870-f5w6fw6q 5027 5 useful useful JJ cord-006870-f5w6fw6q 5027 6 to to TO cord-006870-f5w6fw6q 5027 7 prioritize prioritize VB cord-006870-f5w6fw6q 5027 8 treatments treatment NNS cord-006870-f5w6fw6q 5027 9 worthy worthy JJ cord-006870-f5w6fw6q 5027 10 of of IN cord-006870-f5w6fw6q 5027 11 further further JJ cord-006870-f5w6fw6q 5027 12 study study NN cord-006870-f5w6fw6q 5027 13 . . . cord-006870-f5w6fw6q 5028 1 Oral oral JJ cord-006870-f5w6fw6q 5028 2 nimodipine nimodipine NN cord-006870-f5w6fw6q 5028 3 is be VBZ cord-006870-f5w6fw6q 5028 4 recommended recommend VBN cord-006870-f5w6fw6q 5028 5 to to TO cord-006870-f5w6fw6q 5028 6 improve improve VB cord-006870-f5w6fw6q 5028 7 outcome outcome NN cord-006870-f5w6fw6q 5028 8 in in IN cord-006870-f5w6fw6q 5028 9 treatment treatment NN cord-006870-f5w6fw6q 5028 10 of of IN cord-006870-f5w6fw6q 5028 11 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5028 12 subarachnoid subarachnoid NNP cord-006870-f5w6fw6q 5028 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5028 14 ( ( -LRB- cord-006870-f5w6fw6q 5028 15 aSAH asah JJ cord-006870-f5w6fw6q 5028 16 ) ) -RRB- cord-006870-f5w6fw6q 5028 17 . . . cord-006870-f5w6fw6q 5029 1 FDA FDA NNP cord-006870-f5w6fw6q 5029 2 approved approve VBD cord-006870-f5w6fw6q 5029 3 nimodipine nimodipine JJ cord-006870-f5w6fw6q 5029 4 liquid liquid JJ cord-006870-f5w6fw6q 5029 5 oral oral JJ cord-006870-f5w6fw6q 5029 6 solution solution NN cord-006870-f5w6fw6q 5029 7 ( ( -LRB- cord-006870-f5w6fw6q 5029 8 NOS NOS NNP cord-006870-f5w6fw6q 5029 9 ) ) -RRB- cord-006870-f5w6fw6q 5029 10 in in IN cord-006870-f5w6fw6q 5029 11 2013 2013 CD cord-006870-f5w6fw6q 5029 12 to to TO cord-006870-f5w6fw6q 5029 13 reduce reduce VB cord-006870-f5w6fw6q 5029 14 complications complication NNS cord-006870-f5w6fw6q 5029 15 associated associate VBN cord-006870-f5w6fw6q 5029 16 with with IN cord-006870-f5w6fw6q 5029 17 administering administer VBG cord-006870-f5w6fw6q 5029 18 nimodipine nimodipine NN cord-006870-f5w6fw6q 5029 19 capsules capsule NNS cord-006870-f5w6fw6q 5029 20 ( ( -LRB- cord-006870-f5w6fw6q 5029 21 NC NC NNP cord-006870-f5w6fw6q 5029 22 ) ) -RRB- cord-006870-f5w6fw6q 5029 23 to to IN cord-006870-f5w6fw6q 5029 24 patients patient NNS cord-006870-f5w6fw6q 5029 25 with with IN cord-006870-f5w6fw6q 5029 26 impaired impaired JJ cord-006870-f5w6fw6q 5029 27 swallow swallow NN cord-006870-f5w6fw6q 5029 28 . . . cord-006870-f5w6fw6q 5030 1 Experience experience NN cord-006870-f5w6fw6q 5030 2 with with IN cord-006870-f5w6fw6q 5030 3 NOS NOS NNP cord-006870-f5w6fw6q 5030 4 at at IN cord-006870-f5w6fw6q 5030 5 our -PRON- PRP$ cord-006870-f5w6fw6q 5030 6 center center NN cord-006870-f5w6fw6q 5030 7 has have VBZ cord-006870-f5w6fw6q 5030 8 been be VBN cord-006870-f5w6fw6q 5030 9 complicated complicate VBN cord-006870-f5w6fw6q 5030 10 by by IN cord-006870-f5w6fw6q 5030 11 increased increase VBN cord-006870-f5w6fw6q 5030 12 liquid liquid JJ cord-006870-f5w6fw6q 5030 13 bowel bowel NN cord-006870-f5w6fw6q 5030 14 movements movement NNS cord-006870-f5w6fw6q 5030 15 ( ( -LRB- cord-006870-f5w6fw6q 5030 16 LBM LBM NNP cord-006870-f5w6fw6q 5030 17 ) ) -RRB- cord-006870-f5w6fw6q 5030 18 prompting prompt VBG cord-006870-f5w6fw6q 5030 19 unnecessary unnecessary JJ cord-006870-f5w6fw6q 5030 20 testing testing NN cord-006870-f5w6fw6q 5030 21 for for IN cord-006870-f5w6fw6q 5030 22 infectious infectious JJ cord-006870-f5w6fw6q 5030 23 diarrhea diarrhea NN cord-006870-f5w6fw6q 5030 24 and and CC cord-006870-f5w6fw6q 5030 25 exposure exposure NN cord-006870-f5w6fw6q 5030 26 to to IN cord-006870-f5w6fw6q 5030 27 invasive invasive JJ cord-006870-f5w6fw6q 5030 28 fecal fecal JJ cord-006870-f5w6fw6q 5030 29 management management NN cord-006870-f5w6fw6q 5030 30 devices device NNS cord-006870-f5w6fw6q 5030 31 . . . cord-006870-f5w6fw6q 5031 1 Study study NN cord-006870-f5w6fw6q 5031 2 approved approve VBN cord-006870-f5w6fw6q 5031 3 by by IN cord-006870-f5w6fw6q 5031 4 local local JJ cord-006870-f5w6fw6q 5031 5 Qualtiy Qualtiy NNP cord-006870-f5w6fw6q 5031 6 Improvement Improvement NNP cord-006870-f5w6fw6q 5031 7 Review Review NNP cord-006870-f5w6fw6q 5031 8 Committee Committee NNP cord-006870-f5w6fw6q 5031 9 . . . cord-006870-f5w6fw6q 5032 1 Data datum NNS cord-006870-f5w6fw6q 5032 2 was be VBD cord-006870-f5w6fw6q 5032 3 collected collect VBN cord-006870-f5w6fw6q 5032 4 prospectively prospectively RB cord-006870-f5w6fw6q 5032 5 in in IN cord-006870-f5w6fw6q 5032 6 consecutive consecutive JJ cord-006870-f5w6fw6q 5032 7 patients patient NNS cord-006870-f5w6fw6q 5032 8 diagnosed diagnose VBN cord-006870-f5w6fw6q 5032 9 with with IN cord-006870-f5w6fw6q 5032 10 aSAH asah JJ cord-006870-f5w6fw6q 5032 11 during during IN cord-006870-f5w6fw6q 5032 12 intensive intensive JJ cord-006870-f5w6fw6q 5032 13 care care NN cord-006870-f5w6fw6q 5032 14 unit unit NN cord-006870-f5w6fw6q 5032 15 ( ( -LRB- cord-006870-f5w6fw6q 5032 16 ICU ICU NNP cord-006870-f5w6fw6q 5032 17 ) ) -RRB- cord-006870-f5w6fw6q 5032 18 course course NN cord-006870-f5w6fw6q 5032 19 . . . cord-006870-f5w6fw6q 5033 1 Formulations formulation NNS cord-006870-f5w6fw6q 5033 2 of of IN cord-006870-f5w6fw6q 5033 3 nimodipine nimodipine NN cord-006870-f5w6fw6q 5033 4 available available JJ cord-006870-f5w6fw6q 5033 5 were be VBD cord-006870-f5w6fw6q 5033 6 generic generic JJ cord-006870-f5w6fw6q 5033 7 NC NC NNP cord-006870-f5w6fw6q 5033 8 ( ( -LRB- cord-006870-f5w6fw6q 5033 9 Heritage Heritage NNP cord-006870-f5w6fw6q 5033 10 Pharmaceutical Pharmaceutical NNP cord-006870-f5w6fw6q 5033 11 ) ) -RRB- cord-006870-f5w6fw6q 5033 12 and and CC cord-006870-f5w6fw6q 5033 13 NOS NOS NNP cord-006870-f5w6fw6q 5033 14 ( ( -LRB- cord-006870-f5w6fw6q 5033 15 Arbor Arbor NNP cord-006870-f5w6fw6q 5033 16 Pharmaceuticals Pharmaceuticals NNPS cord-006870-f5w6fw6q 5033 17 ) ) -RRB- cord-006870-f5w6fw6q 5033 18 . . . cord-006870-f5w6fw6q 5034 1 We -PRON- PRP cord-006870-f5w6fw6q 5034 2 examined examine VBD cord-006870-f5w6fw6q 5034 3 total total JJ cord-006870-f5w6fw6q 5034 4 ICU ICU NNP cord-006870-f5w6fw6q 5034 5 days day NNS cord-006870-f5w6fw6q 5034 6 exposed expose VBN cord-006870-f5w6fw6q 5034 7 to to IN cord-006870-f5w6fw6q 5034 8 NOS NOS NNP cord-006870-f5w6fw6q 5034 9 , , , cord-006870-f5w6fw6q 5034 10 ICU ICU NNP cord-006870-f5w6fw6q 5034 11 days day NNS cord-006870-f5w6fw6q 5034 12 with with IN cord-006870-f5w6fw6q 5034 13 LBM LBM NNP cord-006870-f5w6fw6q 5034 14 , , , cord-006870-f5w6fw6q 5034 15 infectious infectious JJ cord-006870-f5w6fw6q 5034 16 diarrhea diarrhea NN cord-006870-f5w6fw6q 5034 17 investigations investigation NNS cord-006870-f5w6fw6q 5034 18 , , , cord-006870-f5w6fw6q 5034 19 and and CC cord-006870-f5w6fw6q 5034 20 fecal fecal JJ cord-006870-f5w6fw6q 5034 21 management management NN cord-006870-f5w6fw6q 5034 22 device device NN cord-006870-f5w6fw6q 5034 23 use use NN cord-006870-f5w6fw6q 5034 24 . . . cord-006870-f5w6fw6q 5035 1 All all DT cord-006870-f5w6fw6q 5035 2 statistical statistical JJ cord-006870-f5w6fw6q 5035 3 tests test NNS cord-006870-f5w6fw6q 5035 4 were be VBD cord-006870-f5w6fw6q 5035 5 performed perform VBN cord-006870-f5w6fw6q 5035 6 using use VBG cord-006870-f5w6fw6q 5035 7 Minitab Minitab NNP cord-006870-f5w6fw6q 5035 8 . . . cord-006870-f5w6fw6q 5036 1 27 27 CD cord-006870-f5w6fw6q 5036 2 patients patient NNS cord-006870-f5w6fw6q 5036 3 were be VBD cord-006870-f5w6fw6q 5036 4 studied study VBN cord-006870-f5w6fw6q 5036 5 from from IN cord-006870-f5w6fw6q 5036 6 3/6/2017 3/6/2017 CD cord-006870-f5w6fw6q 5036 7 to to IN cord-006870-f5w6fw6q 5036 8 6/23/2017 6/23/2017 CD cord-006870-f5w6fw6q 5036 9 ; ; : cord-006870-f5w6fw6q 5036 10 17 17 CD cord-006870-f5w6fw6q 5036 11 patients patient NNS cord-006870-f5w6fw6q 5036 12 exposed expose VBN cord-006870-f5w6fw6q 5036 13 to to IN cord-006870-f5w6fw6q 5036 14 NOS NOS NNP cord-006870-f5w6fw6q 5036 15 for for IN cord-006870-f5w6fw6q 5036 16 143 143 CD cord-006870-f5w6fw6q 5036 17 ICU ICU NNP cord-006870-f5w6fw6q 5036 18 days day NNS cord-006870-f5w6fw6q 5036 19 , , , cord-006870-f5w6fw6q 5036 20 71 71 CD cord-006870-f5w6fw6q 5036 21 ICU ICU NNP cord-006870-f5w6fw6q 5036 22 days day NNS cord-006870-f5w6fw6q 5036 23 with with IN cord-006870-f5w6fw6q 5036 24 LBM LBM NNP cord-006870-f5w6fw6q 5036 25 , , , cord-006870-f5w6fw6q 5036 26 7 7 CD cord-006870-f5w6fw6q 5036 27 infectious infectious JJ cord-006870-f5w6fw6q 5036 28 diarrhea diarrhea NN cord-006870-f5w6fw6q 5036 29 investigations investigation NNS cord-006870-f5w6fw6q 5036 30 , , , cord-006870-f5w6fw6q 5036 31 and and CC cord-006870-f5w6fw6q 5036 32 5 5 CD cord-006870-f5w6fw6q 5036 33 required required JJ cord-006870-f5w6fw6q 5036 34 fecal fecal JJ cord-006870-f5w6fw6q 5036 35 management management NN cord-006870-f5w6fw6q 5036 36 devices device NNS cord-006870-f5w6fw6q 5036 37 . . . cord-006870-f5w6fw6q 5037 1 17 17 CD cord-006870-f5w6fw6q 5037 2 patients patient NNS cord-006870-f5w6fw6q 5037 3 exposed expose VBN cord-006870-f5w6fw6q 5037 4 to to IN cord-006870-f5w6fw6q 5037 5 NC NC NNP cord-006870-f5w6fw6q 5037 6 for for IN cord-006870-f5w6fw6q 5037 7 154 154 CD cord-006870-f5w6fw6q 5037 8 ICU ICU NNP cord-006870-f5w6fw6q 5037 9 days day NNS cord-006870-f5w6fw6q 5037 10 , , , cord-006870-f5w6fw6q 5037 11 9 9 CD cord-006870-f5w6fw6q 5037 12 ICU ICU NNP cord-006870-f5w6fw6q 5037 13 days day NNS cord-006870-f5w6fw6q 5037 14 with with IN cord-006870-f5w6fw6q 5037 15 LBM LBM NNP cord-006870-f5w6fw6q 5037 16 ( ( -LRB- cord-006870-f5w6fw6q 5037 17 all all DT cord-006870-f5w6fw6q 5037 18 cases case NNS cord-006870-f5w6fw6q 5037 19 were be VBD cord-006870-f5w6fw6q 5037 20 also also RB cord-006870-f5w6fw6q 5037 21 received receive VBN cord-006870-f5w6fw6q 5037 22 NOS NOS NNP cord-006870-f5w6fw6q 5037 23 ) ) -RRB- cord-006870-f5w6fw6q 5037 24 , , , cord-006870-f5w6fw6q 5037 25 no no DT cord-006870-f5w6fw6q 5037 26 infectious infectious JJ cord-006870-f5w6fw6q 5037 27 diarrhea diarrhea NN cord-006870-f5w6fw6q 5037 28 investigations investigation NNS cord-006870-f5w6fw6q 5037 29 , , , cord-006870-f5w6fw6q 5037 30 and and CC cord-006870-f5w6fw6q 5037 31 no no DT cord-006870-f5w6fw6q 5037 32 fecal fecal JJ cord-006870-f5w6fw6q 5037 33 management management NN cord-006870-f5w6fw6q 5037 34 device device NN cord-006870-f5w6fw6q 5037 35 requirements requirement NNS cord-006870-f5w6fw6q 5037 36 . . . cord-006870-f5w6fw6q 5038 1 Odds odd NNS cord-006870-f5w6fw6q 5038 2 ratio ratio NN cord-006870-f5w6fw6q 5038 3 for for IN cord-006870-f5w6fw6q 5038 4 LBM lbm NN cord-006870-f5w6fw6q 5038 5 with with IN cord-006870-f5w6fw6q 5038 6 exposure exposure NN cord-006870-f5w6fw6q 5038 7 to to IN cord-006870-f5w6fw6q 5038 8 NOS NOS NNP cord-006870-f5w6fw6q 5038 9 was be VBD cord-006870-f5w6fw6q 5038 10 15.9 15.9 CD cord-006870-f5w6fw6q 5038 11 ( ( -LRB- cord-006870-f5w6fw6q 5038 12 95 95 CD cord-006870-f5w6fw6q 5038 13 % % NN cord-006870-f5w6fw6q 5038 14 CI CI NNP cord-006870-f5w6fw6q 5038 15 7.5 7.5 CD cord-006870-f5w6fw6q 5038 16 to to IN cord-006870-f5w6fw6q 5038 17 33.5 33.5 CD cord-006870-f5w6fw6q 5038 18 , , , cord-006870-f5w6fw6q 5038 19 p p NN cord-006870-f5w6fw6q 5038 20 < < XX cord-006870-f5w6fw6q 5038 21 0.0001 0.0001 CD cord-006870-f5w6fw6q 5038 22 ) ) -RRB- cord-006870-f5w6fw6q 5038 23 . . . cord-006870-f5w6fw6q 5039 1 The the DT cord-006870-f5w6fw6q 5039 2 high high JJ cord-006870-f5w6fw6q 5039 3 incidence incidence NN cord-006870-f5w6fw6q 5039 4 of of IN cord-006870-f5w6fw6q 5039 5 LBM LBM NNP cord-006870-f5w6fw6q 5039 6 with with IN cord-006870-f5w6fw6q 5039 7 NOS NOS NNP cord-006870-f5w6fw6q 5039 8 resulted result VBD cord-006870-f5w6fw6q 5039 9 in in IN cord-006870-f5w6fw6q 5039 10 more more RBR cord-006870-f5w6fw6q 5039 11 infectious infectious JJ cord-006870-f5w6fw6q 5039 12 diarrhea diarrhea NN cord-006870-f5w6fw6q 5039 13 testing testing NN cord-006870-f5w6fw6q 5039 14 and and CC cord-006870-f5w6fw6q 5039 15 fecal fecal JJ cord-006870-f5w6fw6q 5039 16 management management NN cord-006870-f5w6fw6q 5039 17 device device NN cord-006870-f5w6fw6q 5039 18 use use NN cord-006870-f5w6fw6q 5039 19 . . . cord-006870-f5w6fw6q 5040 1 Uncontrolled uncontrolled JJ cord-006870-f5w6fw6q 5040 2 diarrhea diarrhea NN cord-006870-f5w6fw6q 5040 3 may may MD cord-006870-f5w6fw6q 5040 4 increase increase VB cord-006870-f5w6fw6q 5040 5 risk risk NN cord-006870-f5w6fw6q 5040 6 for for IN cord-006870-f5w6fw6q 5040 7 dehydration dehydration NN cord-006870-f5w6fw6q 5040 8 and and CC cord-006870-f5w6fw6q 5040 9 delayed delay VBN cord-006870-f5w6fw6q 5040 10 cerebral cerebral JJ cord-006870-f5w6fw6q 5040 11 ischemia ischemia NN cord-006870-f5w6fw6q 5040 12 , , , cord-006870-f5w6fw6q 5040 13 although although IN cord-006870-f5w6fw6q 5040 14 this this DT cord-006870-f5w6fw6q 5040 15 is be VBZ cord-006870-f5w6fw6q 5040 16 not not RB cord-006870-f5w6fw6q 5040 17 explored explore VBN cord-006870-f5w6fw6q 5040 18 in in IN cord-006870-f5w6fw6q 5040 19 the the DT cord-006870-f5w6fw6q 5040 20 current current JJ cord-006870-f5w6fw6q 5040 21 study study NN cord-006870-f5w6fw6q 5040 22 . . . cord-006870-f5w6fw6q 5041 1 NOS NOS NNP cord-006870-f5w6fw6q 5041 2 can can MD cord-006870-f5w6fw6q 5041 3 mitigate mitigate VB cord-006870-f5w6fw6q 5041 4 risks risk NNS cord-006870-f5w6fw6q 5041 5 associated associate VBN cord-006870-f5w6fw6q 5041 6 with with IN cord-006870-f5w6fw6q 5041 7 needle needle NN cord-006870-f5w6fw6q 5041 8 aspiration aspiration NN cord-006870-f5w6fw6q 5041 9 of of IN cord-006870-f5w6fw6q 5041 10 NC NC NNP cord-006870-f5w6fw6q 5041 11 , , , cord-006870-f5w6fw6q 5041 12 however however RB cord-006870-f5w6fw6q 5041 13 these these DT cord-006870-f5w6fw6q 5041 14 issues issue NNS cord-006870-f5w6fw6q 5041 15 coupled couple VBN cord-006870-f5w6fw6q 5041 16 with with IN cord-006870-f5w6fw6q 5041 17 higher high JJR cord-006870-f5w6fw6q 5041 18 cost cost NN cord-006870-f5w6fw6q 5041 19 may may MD cord-006870-f5w6fw6q 5041 20 limit limit VB cord-006870-f5w6fw6q 5041 21 benefit benefit NN cord-006870-f5w6fw6q 5041 22 of of IN cord-006870-f5w6fw6q 5041 23 its -PRON- PRP$ cord-006870-f5w6fw6q 5041 24 use use NN cord-006870-f5w6fw6q 5041 25 . . . cord-006870-f5w6fw6q 5042 1 Possible possible JJ cord-006870-f5w6fw6q 5042 2 solutions solution NNS cord-006870-f5w6fw6q 5042 3 may may MD cord-006870-f5w6fw6q 5042 4 include include VB cord-006870-f5w6fw6q 5042 5 compounding compound VBG cord-006870-f5w6fw6q 5042 6 NC NC NNP cord-006870-f5w6fw6q 5042 7 into into IN cord-006870-f5w6fw6q 5042 8 a a DT cord-006870-f5w6fw6q 5042 9 liquid liquid JJ cord-006870-f5w6fw6q 5042 10 formulation formulation NN cord-006870-f5w6fw6q 5042 11 by by IN cord-006870-f5w6fw6q 5042 12 pharmacists pharmacist NNS cord-006870-f5w6fw6q 5042 13 or or CC cord-006870-f5w6fw6q 5042 14 pharmacy pharmacy NN cord-006870-f5w6fw6q 5042 15 technicians technician NNS cord-006870-f5w6fw6q 5042 16 . . . cord-006870-f5w6fw6q 5043 1 Possible possible JJ cord-006870-f5w6fw6q 5043 2 safety safety NN cord-006870-f5w6fw6q 5043 3 and and CC cord-006870-f5w6fw6q 5043 4 cost cost NN cord-006870-f5w6fw6q 5043 5 benefits benefit NNS cord-006870-f5w6fw6q 5043 6 require require VBP cord-006870-f5w6fw6q 5043 7 further further JJ cord-006870-f5w6fw6q 5043 8 investigation investigation NN cord-006870-f5w6fw6q 5043 9 . . . cord-006870-f5w6fw6q 5044 1 Headache headache NN cord-006870-f5w6fw6q 5044 2 ( ( -LRB- cord-006870-f5w6fw6q 5044 3 HA HA NNP cord-006870-f5w6fw6q 5044 4 ) ) -RRB- cord-006870-f5w6fw6q 5044 5 management management NN cord-006870-f5w6fw6q 5044 6 after after IN cord-006870-f5w6fw6q 5044 7 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5044 8 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5044 9 ( ( -LRB- cord-006870-f5w6fw6q 5044 10 SAH SAH NNP cord-006870-f5w6fw6q 5044 11 ) ) -RRB- cord-006870-f5w6fw6q 5044 12 is be VBZ cord-006870-f5w6fw6q 5044 13 challenging challenging JJ cord-006870-f5w6fw6q 5044 14 and and CC cord-006870-f5w6fw6q 5044 15 lacks lack VBZ cord-006870-f5w6fw6q 5044 16 standardization standardization NN cord-006870-f5w6fw6q 5044 17 . . . cord-006870-f5w6fw6q 5045 1 We -PRON- PRP cord-006870-f5w6fw6q 5045 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 5045 3 that that IN cord-006870-f5w6fw6q 5045 4 inadequate inadequate JJ cord-006870-f5w6fw6q 5045 5 inpatient inpatient JJ cord-006870-f5w6fw6q 5045 6 HA HA NNP cord-006870-f5w6fw6q 5045 7 pain pain NN cord-006870-f5w6fw6q 5045 8 management management NN cord-006870-f5w6fw6q 5045 9 leads lead VBZ cord-006870-f5w6fw6q 5045 10 to to IN cord-006870-f5w6fw6q 5045 11 the the DT cord-006870-f5w6fw6q 5045 12 development development NN cord-006870-f5w6fw6q 5045 13 of of IN cord-006870-f5w6fw6q 5045 14 chronic chronic JJ cord-006870-f5w6fw6q 5045 15 HA HA NNP cord-006870-f5w6fw6q 5045 16 ( ( -LRB- cord-006870-f5w6fw6q 5045 17 cHA cha NN cord-006870-f5w6fw6q 5045 18 ) ) -RRB- cord-006870-f5w6fw6q 5045 19 after after IN cord-006870-f5w6fw6q 5045 20 SAH SAH NNP cord-006870-f5w6fw6q 5045 21 . . . cord-006870-f5w6fw6q 5046 1 Prospective prospective JJ cord-006870-f5w6fw6q 5046 2 , , , cord-006870-f5w6fw6q 5046 3 observational observational JJ cord-006870-f5w6fw6q 5046 4 study study NN cord-006870-f5w6fw6q 5046 5 of of IN cord-006870-f5w6fw6q 5046 6 non non JJ cord-006870-f5w6fw6q 5046 7 - - JJ cord-006870-f5w6fw6q 5046 8 traumatic traumatic JJ cord-006870-f5w6fw6q 5046 9 Hunt Hunt NNP cord-006870-f5w6fw6q 5046 10 and and CC cord-006870-f5w6fw6q 5046 11 Hess Hess NNP cord-006870-f5w6fw6q 5046 12 ( ( -LRB- cord-006870-f5w6fw6q 5046 13 HH HH NNP cord-006870-f5w6fw6q 5046 14 ) ) -RRB- cord-006870-f5w6fw6q 5046 15 grades grade NNS cord-006870-f5w6fw6q 5046 16 I I NNP cord-006870-f5w6fw6q 5046 17 - - HYPH cord-006870-f5w6fw6q 5046 18 III III NNP cord-006870-f5w6fw6q 5046 19 SAH SAH NNP cord-006870-f5w6fw6q 5046 20 patients patient NNS cord-006870-f5w6fw6q 5046 21 admitted admit VBD cord-006870-f5w6fw6q 5046 22 from from IN cord-006870-f5w6fw6q 5046 23 2/2014 2/2014 NNS cord-006870-f5w6fw6q 5046 24 to to IN cord-006870-f5w6fw6q 5046 25 12/2014 12/2014 CD cord-006870-f5w6fw6q 5046 26 . . . cord-006870-f5w6fw6q 5047 1 After after IN cord-006870-f5w6fw6q 5047 2 informed informed JJ cord-006870-f5w6fw6q 5047 3 consent consent NN cord-006870-f5w6fw6q 5047 4 we -PRON- PRP cord-006870-f5w6fw6q 5047 5 recorded record VBD cord-006870-f5w6fw6q 5047 6 demographics demographic NNS cord-006870-f5w6fw6q 5047 7 , , , cord-006870-f5w6fw6q 5047 8 clinical clinical JJ cord-006870-f5w6fw6q 5047 9 and and CC cord-006870-f5w6fw6q 5047 10 radiographic radiographic JJ cord-006870-f5w6fw6q 5047 11 features feature NNS cord-006870-f5w6fw6q 5047 12 , , , cord-006870-f5w6fw6q 5047 13 analgesic analgesic JJ cord-006870-f5w6fw6q 5047 14 and and CC cord-006870-f5w6fw6q 5047 15 steroid steroid JJ cord-006870-f5w6fw6q 5047 16 doses dose NNS cord-006870-f5w6fw6q 5047 17 , , , cord-006870-f5w6fw6q 5047 18 hospital hospital NN cord-006870-f5w6fw6q 5047 19 course course NN cord-006870-f5w6fw6q 5047 20 and and CC cord-006870-f5w6fw6q 5047 21 inpatient inpatient JJ cord-006870-f5w6fw6q 5047 22 pain pain NN cord-006870-f5w6fw6q 5047 23 scores score NNS cord-006870-f5w6fw6q 5047 24 using use VBG cord-006870-f5w6fw6q 5047 25 Numeric numeric JJ cord-006870-f5w6fw6q 5047 26 Rating Rating NNP cord-006870-f5w6fw6q 5047 27 Scale scale NN cord-006870-f5w6fw6q 5047 28 ( ( -LRB- cord-006870-f5w6fw6q 5047 29 NRS nrs NN cord-006870-f5w6fw6q 5047 30 , , , cord-006870-f5w6fw6q 5047 31 0 0 CD cord-006870-f5w6fw6q 5047 32 - - SYM cord-006870-f5w6fw6q 5047 33 10 10 CD cord-006870-f5w6fw6q 5047 34 ) ) -RRB- cord-006870-f5w6fw6q 5047 35 before before IN cord-006870-f5w6fw6q 5047 36 ( ( -LRB- cord-006870-f5w6fw6q 5047 37 NRS NRS NNP cord-006870-f5w6fw6q 5047 38 - - HYPH cord-006870-f5w6fw6q 5047 39 pre pre NNP cord-006870-f5w6fw6q 5047 40 ) ) -RRB- cord-006870-f5w6fw6q 5047 41 and and CC cord-006870-f5w6fw6q 5047 42 after after IN cord-006870-f5w6fw6q 5047 43 each each DT cord-006870-f5w6fw6q 5047 44 analgesic analgesic JJ cord-006870-f5w6fw6q 5047 45 administration administration NN cord-006870-f5w6fw6q 5047 46 over over IN cord-006870-f5w6fw6q 5047 47 post post JJ cord-006870-f5w6fw6q 5047 48 - - JJ cord-006870-f5w6fw6q 5047 49 bleed bleed JJ cord-006870-f5w6fw6q 5047 50 days day NNS cord-006870-f5w6fw6q 5047 51 0 0 CD cord-006870-f5w6fw6q 5047 52 - - SYM cord-006870-f5w6fw6q 5047 53 14 14 CD cord-006870-f5w6fw6q 5047 54 . . . cord-006870-f5w6fw6q 5048 1 A a DT cord-006870-f5w6fw6q 5048 2 phone phone NN cord-006870-f5w6fw6q 5048 3 survey survey NN cord-006870-f5w6fw6q 5048 4 administered administer VBD cord-006870-f5w6fw6q 5048 5 12 12 CD cord-006870-f5w6fw6q 5048 6 - - SYM cord-006870-f5w6fw6q 5048 7 24 24 CD cord-006870-f5w6fw6q 5048 8 months month NNS cord-006870-f5w6fw6q 5048 9 after after IN cord-006870-f5w6fw6q 5048 10 admission admission NN cord-006870-f5w6fw6q 5048 11 evaluated evaluate VBD cord-006870-f5w6fw6q 5048 12 cHA cha PRP cord-006870-f5w6fw6q 5048 13 burden burden NN cord-006870-f5w6fw6q 5048 14 . . . cord-006870-f5w6fw6q 5049 1 Inpatient Inpatient NNP cord-006870-f5w6fw6q 5049 2 HA HA NNP cord-006870-f5w6fw6q 5049 3 control control NN cord-006870-f5w6fw6q 5049 4 effectiveness effectiveness NN cord-006870-f5w6fw6q 5049 5 was be VBD cord-006870-f5w6fw6q 5049 6 evaluated evaluate VBN cord-006870-f5w6fw6q 5049 7 by by IN cord-006870-f5w6fw6q 5049 8 percent percent NN cord-006870-f5w6fw6q 5049 9 pain pain NN cord-006870-f5w6fw6q 5049 10 resolution resolution NN cord-006870-f5w6fw6q 5049 11 from from IN cord-006870-f5w6fw6q 5049 12 initial initial JJ cord-006870-f5w6fw6q 5049 13 pain pain NN cord-006870-f5w6fw6q 5049 14 score score NN cord-006870-f5w6fw6q 5049 15 , , , cord-006870-f5w6fw6q 5049 16 using use VBG cord-006870-f5w6fw6q 5049 17 NRS NRS NNP cord-006870-f5w6fw6q 5049 18 - - HYPH cord-006870-f5w6fw6q 5049 19 pre pre JJ cord-006870-f5w6fw6q 5049 20 . . . cord-006870-f5w6fw6q 5050 1 The the DT cord-006870-f5w6fw6q 5050 2 percentage percentage NN cord-006870-f5w6fw6q 5050 3 of of IN cord-006870-f5w6fw6q 5050 4 administrations administration NNS cord-006870-f5w6fw6q 5050 5 yielding yield VBG cord-006870-f5w6fw6q 5050 6 full full JJ cord-006870-f5w6fw6q 5050 7 pain pain NN cord-006870-f5w6fw6q 5050 8 resolution resolution NN cord-006870-f5w6fw6q 5050 9 was be VBD cord-006870-f5w6fw6q 5050 10 compared compare VBN cord-006870-f5w6fw6q 5050 11 between between IN cord-006870-f5w6fw6q 5050 12 those those DT cord-006870-f5w6fw6q 5050 13 with with IN cord-006870-f5w6fw6q 5050 14 and and CC cord-006870-f5w6fw6q 5050 15 without without IN cord-006870-f5w6fw6q 5050 16 cHA cha PRP cord-006870-f5w6fw6q 5050 17 . . . cord-006870-f5w6fw6q 5051 1 Chi Chi NNP cord-006870-f5w6fw6q 5051 2 - - HYPH cord-006870-f5w6fw6q 5051 3 square square NNP cord-006870-f5w6fw6q 5051 4 and and CC cord-006870-f5w6fw6q 5051 5 t t NN cord-006870-f5w6fw6q 5051 6 - - HYPH cord-006870-f5w6fw6q 5051 7 tests test NNS cord-006870-f5w6fw6q 5051 8 were be VBD cord-006870-f5w6fw6q 5051 9 used use VBN cord-006870-f5w6fw6q 5051 10 for for IN cord-006870-f5w6fw6q 5051 11 statistical statistical JJ cord-006870-f5w6fw6q 5051 12 analyses analysis NNS cord-006870-f5w6fw6q 5051 13 . . . cord-006870-f5w6fw6q 5052 1 29 29 CD cord-006870-f5w6fw6q 5052 2 patients patient NNS cord-006870-f5w6fw6q 5052 3 , , , cord-006870-f5w6fw6q 5052 4 69 69 CD cord-006870-f5w6fw6q 5052 5 % % NN cord-006870-f5w6fw6q 5052 6 female female NN cord-006870-f5w6fw6q 5052 7 , , , cord-006870-f5w6fw6q 5052 8 mean mean VB cord-006870-f5w6fw6q 5052 9 age age NN cord-006870-f5w6fw6q 5052 10 54.8 54.8 CD cord-006870-f5w6fw6q 5052 11 ±11.4 ±11.4 CD cord-006870-f5w6fw6q 5052 12 years year NNS cord-006870-f5w6fw6q 5052 13 with with IN cord-006870-f5w6fw6q 5052 14 HH HH NNP cord-006870-f5w6fw6q 5052 15 grade grade NN cord-006870-f5w6fw6q 5052 16 I -PRON- PRP cord-006870-f5w6fw6q 5052 17 ( ( -LRB- cord-006870-f5w6fw6q 5052 18 6/29 6/29 CD cord-006870-f5w6fw6q 5052 19 ) ) -RRB- cord-006870-f5w6fw6q 5052 20 , , , cord-006870-f5w6fw6q 5052 21 II II NNP cord-006870-f5w6fw6q 5052 22 ( ( -LRB- cord-006870-f5w6fw6q 5052 23 16/29 16/29 CD cord-006870-f5w6fw6q 5052 24 ) ) -RRB- cord-006870-f5w6fw6q 5052 25 , , , cord-006870-f5w6fw6q 5052 26 and and CC cord-006870-f5w6fw6q 5052 27 III III NNP cord-006870-f5w6fw6q 5053 1 ( ( -LRB- cord-006870-f5w6fw6q 5053 2 7/29 7/29 CD cord-006870-f5w6fw6q 5053 3 ) ) -RRB- cord-006870-f5w6fw6q 5053 4 SAH SAH NNP cord-006870-f5w6fw6q 5053 5 were be VBD cord-006870-f5w6fw6q 5053 6 enrolled enrol VBN cord-006870-f5w6fw6q 5053 7 with with IN cord-006870-f5w6fw6q 5053 8 7 7 CD cord-006870-f5w6fw6q 5053 9 lost lose VBN cord-006870-f5w6fw6q 5053 10 to to TO cord-006870-f5w6fw6q 5053 11 follow follow VB cord-006870-f5w6fw6q 5053 12 - - HYPH cord-006870-f5w6fw6q 5053 13 up up NN cord-006870-f5w6fw6q 5053 14 . . . cord-006870-f5w6fw6q 5054 1 At at IN cord-006870-f5w6fw6q 5054 2 follow follow NN cord-006870-f5w6fw6q 5054 3 - - HYPH cord-006870-f5w6fw6q 5054 4 up up NN cord-006870-f5w6fw6q 5054 5 , , , cord-006870-f5w6fw6q 5054 6 27.3 27.3 CD cord-006870-f5w6fw6q 5054 7 % % NN cord-006870-f5w6fw6q 5054 8 patients patient NNS cord-006870-f5w6fw6q 5054 9 ( ( -LRB- cord-006870-f5w6fw6q 5054 10 6/22 6/22 CD cord-006870-f5w6fw6q 5054 11 ) ) -RRB- cord-006870-f5w6fw6q 5054 12 reported report VBD cord-006870-f5w6fw6q 5054 13 daily daily RB cord-006870-f5w6fw6q 5054 14 HA HA NNP cord-006870-f5w6fw6q 5054 15 , , , cord-006870-f5w6fw6q 5054 16 13.6 13.6 CD cord-006870-f5w6fw6q 5054 17 % % NN cord-006870-f5w6fw6q 5054 18 ( ( -LRB- cord-006870-f5w6fw6q 5054 19 3/22 3/22 CD cord-006870-f5w6fw6q 5054 20 ) ) -RRB- cord-006870-f5w6fw6q 5054 21 occasional occasional JJ cord-006870-f5w6fw6q 5054 22 HA HA NNP cord-006870-f5w6fw6q 5054 23 , , , cord-006870-f5w6fw6q 5054 24 and and CC cord-006870-f5w6fw6q 5054 25 59 59 CD cord-006870-f5w6fw6q 5054 26 % % NN cord-006870-f5w6fw6q 5054 27 ( ( -LRB- cord-006870-f5w6fw6q 5054 28 13/22 13/22 CD cord-006870-f5w6fw6q 5054 29 ) ) -RRB- cord-006870-f5w6fw6q 5054 30 no no DT cord-006870-f5w6fw6q 5054 31 HA HA NNP cord-006870-f5w6fw6q 5054 32 . . . cord-006870-f5w6fw6q 5055 1 Full full JJ cord-006870-f5w6fw6q 5055 2 pain pain NN cord-006870-f5w6fw6q 5055 3 resolution resolution NN cord-006870-f5w6fw6q 5055 4 after after IN cord-006870-f5w6fw6q 5055 5 analgesic analgesic JJ cord-006870-f5w6fw6q 5055 6 administration administration NN cord-006870-f5w6fw6q 5055 7 was be VBD cord-006870-f5w6fw6q 5055 8 associated associate VBN cord-006870-f5w6fw6q 5055 9 with with IN cord-006870-f5w6fw6q 5055 10 less less JJR cord-006870-f5w6fw6q 5055 11 cHA cHA NNS cord-006870-f5w6fw6q 5055 12 ( ( -LRB- cord-006870-f5w6fw6q 5055 13 57 57 CD cord-006870-f5w6fw6q 5055 14 [ [ -LRB- cord-006870-f5w6fw6q 5055 15 17.4 17.4 CD cord-006870-f5w6fw6q 5055 16 % % NN cord-006870-f5w6fw6q 5055 17 ] ] -RRB- cord-006870-f5w6fw6q 5055 18 vs. vs. FW cord-006870-f5w6fw6q 5055 19 80 80 CD cord-006870-f5w6fw6q 5055 20 [ [ -LRB- cord-006870-f5w6fw6q 5055 21 24.3 24.3 CD cord-006870-f5w6fw6q 5055 22 % % NN cord-006870-f5w6fw6q 5055 23 ] ] -RRB- cord-006870-f5w6fw6q 5055 24 , , , cord-006870-f5w6fw6q 5055 25 p=0.029 p=0.029 NNP cord-006870-f5w6fw6q 5055 26 ) ) -RRB- cord-006870-f5w6fw6q 5055 27 . . . cord-006870-f5w6fw6q 5056 1 Mean mean JJ cord-006870-f5w6fw6q 5056 2 daily daily JJ cord-006870-f5w6fw6q 5056 3 inpatient inpatient JJ cord-006870-f5w6fw6q 5056 4 opioid opioid NN cord-006870-f5w6fw6q 5056 5 dose dose NN cord-006870-f5w6fw6q 5056 6 ( ( -LRB- cord-006870-f5w6fw6q 5056 7 morphine morphine NN cord-006870-f5w6fw6q 5056 8 equivalents equivalent NNS cord-006870-f5w6fw6q 5056 9 ) ) -RRB- cord-006870-f5w6fw6q 5056 10 for for IN cord-006870-f5w6fw6q 5056 11 patients patient NNS cord-006870-f5w6fw6q 5056 12 with with IN cord-006870-f5w6fw6q 5056 13 and and CC cord-006870-f5w6fw6q 5056 14 without without IN cord-006870-f5w6fw6q 5056 15 cHA cha PRP cord-006870-f5w6fw6q 5056 16 was be VBD cord-006870-f5w6fw6q 5056 17 14.9 14.9 CD cord-006870-f5w6fw6q 5056 18 mg mg NNS cord-006870-f5w6fw6q 5056 19 and and CC cord-006870-f5w6fw6q 5056 20 8.9 8.9 CD cord-006870-f5w6fw6q 5056 21 mg mg NNS cord-006870-f5w6fw6q 5056 22 , , , cord-006870-f5w6fw6q 5056 23 respectively respectively RB cord-006870-f5w6fw6q 5056 24 ( ( -LRB- cord-006870-f5w6fw6q 5056 25 p=0.28 p=0.28 NNP cord-006870-f5w6fw6q 5056 26 ) ) -RRB- cord-006870-f5w6fw6q 5056 27 . . . cord-006870-f5w6fw6q 5057 1 Mean mean JJ cord-006870-f5w6fw6q 5057 2 NRS NRS NNP cord-006870-f5w6fw6q 5057 3 - - HYPH cord-006870-f5w6fw6q 5057 4 pre pre NNP cord-006870-f5w6fw6q 5057 5 were be VBD cord-006870-f5w6fw6q 5057 6 4.94 4.94 CD cord-006870-f5w6fw6q 5057 7 vs vs IN cord-006870-f5w6fw6q 5057 8 4.12 4.12 CD cord-006870-f5w6fw6q 5057 9 for for IN cord-006870-f5w6fw6q 5057 10 patients patient NNS cord-006870-f5w6fw6q 5057 11 with with IN cord-006870-f5w6fw6q 5057 12 vs vs RB cord-006870-f5w6fw6q 5057 13 without without IN cord-006870-f5w6fw6q 5057 14 cHA cha PRP cord-006870-f5w6fw6q 5057 15 , , , cord-006870-f5w6fw6q 5057 16 respectively respectively RB cord-006870-f5w6fw6q 5057 17 ( ( -LRB- cord-006870-f5w6fw6q 5057 18 p=0.05 p=0.05 JJ cord-006870-f5w6fw6q 5057 19 ) ) -RRB- cord-006870-f5w6fw6q 5057 20 . . . cord-006870-f5w6fw6q 5058 1 Inpatient inpatient JJ cord-006870-f5w6fw6q 5058 2 analgesia analgesia NN cord-006870-f5w6fw6q 5058 3 for for IN cord-006870-f5w6fw6q 5058 4 SAH SAH NNP cord-006870-f5w6fw6q 5058 5 - - HYPH cord-006870-f5w6fw6q 5058 6 related relate VBN cord-006870-f5w6fw6q 5058 7 HA HA NNP cord-006870-f5w6fw6q 5058 8 is be VBZ cord-006870-f5w6fw6q 5058 9 inadequate inadequate JJ cord-006870-f5w6fw6q 5058 10 and and CC cord-006870-f5w6fw6q 5058 11 may may MD cord-006870-f5w6fw6q 5058 12 be be VB cord-006870-f5w6fw6q 5058 13 associated associate VBN cord-006870-f5w6fw6q 5058 14 with with IN cord-006870-f5w6fw6q 5058 15 the the DT cord-006870-f5w6fw6q 5058 16 development development NN cord-006870-f5w6fw6q 5058 17 of of IN cord-006870-f5w6fw6q 5058 18 chronic chronic JJ cord-006870-f5w6fw6q 5058 19 HA HA NNP cord-006870-f5w6fw6q 5058 20 . . . cord-006870-f5w6fw6q 5059 1 Patients patient NNS cord-006870-f5w6fw6q 5059 2 with with IN cord-006870-f5w6fw6q 5059 3 cHA cha PRP cord-006870-f5w6fw6q 5059 4 had have VBD cord-006870-f5w6fw6q 5059 5 higher high JJR cord-006870-f5w6fw6q 5059 6 mean mean JJ cord-006870-f5w6fw6q 5059 7 inpatient inpatient JJ cord-006870-f5w6fw6q 5059 8 pain pain NN cord-006870-f5w6fw6q 5059 9 score score NN cord-006870-f5w6fw6q 5059 10 and and CC cord-006870-f5w6fw6q 5059 11 fewer few JJR cord-006870-f5w6fw6q 5059 12 analgesic analgesic JJ cord-006870-f5w6fw6q 5059 13 administrations administration NNS cord-006870-f5w6fw6q 5059 14 resulting result VBG cord-006870-f5w6fw6q 5059 15 in in IN cord-006870-f5w6fw6q 5059 16 complete complete JJ cord-006870-f5w6fw6q 5059 17 pain pain NN cord-006870-f5w6fw6q 5059 18 resolution resolution NN cord-006870-f5w6fw6q 5059 19 . . . cord-006870-f5w6fw6q 5060 1 Inpatient inpatient JJ cord-006870-f5w6fw6q 5060 2 opioid opioid NN cord-006870-f5w6fw6q 5060 3 dose dose NN cord-006870-f5w6fw6q 5060 4 per per IN cord-006870-f5w6fw6q 5060 5 day day NN cord-006870-f5w6fw6q 5060 6 was be VBD cord-006870-f5w6fw6q 5060 7 higher high JJR cord-006870-f5w6fw6q 5060 8 in in IN cord-006870-f5w6fw6q 5060 9 cHA cHA NNS cord-006870-f5w6fw6q 5060 10 group group NN cord-006870-f5w6fw6q 5060 11 , , , cord-006870-f5w6fw6q 5060 12 although although IN cord-006870-f5w6fw6q 5060 13 not not RB cord-006870-f5w6fw6q 5060 14 statistically statistically RB cord-006870-f5w6fw6q 5060 15 significant significant JJ cord-006870-f5w6fw6q 5060 16 . . . cord-006870-f5w6fw6q 5061 1 Additional additional JJ cord-006870-f5w6fw6q 5061 2 research research NN cord-006870-f5w6fw6q 5061 3 is be VBZ cord-006870-f5w6fw6q 5061 4 needed need VBN cord-006870-f5w6fw6q 5061 5 to to TO cord-006870-f5w6fw6q 5061 6 characterize characterize VB cord-006870-f5w6fw6q 5061 7 the the DT cord-006870-f5w6fw6q 5061 8 relationship relationship NN cord-006870-f5w6fw6q 5061 9 between between IN cord-006870-f5w6fw6q 5061 10 inpatient inpatient JJ cord-006870-f5w6fw6q 5061 11 headache headache NN cord-006870-f5w6fw6q 5061 12 management management NN cord-006870-f5w6fw6q 5061 13 and and CC cord-006870-f5w6fw6q 5061 14 chronic chronic JJ cord-006870-f5w6fw6q 5061 15 headache headache NN cord-006870-f5w6fw6q 5061 16 after after IN cord-006870-f5w6fw6q 5061 17 SAH SAH NNP cord-006870-f5w6fw6q 5061 18 . . . cord-006870-f5w6fw6q 5062 1 Subarachnoid subarachnoid IN cord-006870-f5w6fw6q 5062 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5062 3 ( ( -LRB- cord-006870-f5w6fw6q 5062 4 SAH SAH NNP cord-006870-f5w6fw6q 5062 5 ) ) -RRB- cord-006870-f5w6fw6q 5062 6 remains remain VBZ cord-006870-f5w6fw6q 5062 7 a a DT cord-006870-f5w6fw6q 5062 8 significant significant JJ cord-006870-f5w6fw6q 5062 9 cause cause NN cord-006870-f5w6fw6q 5062 10 of of IN cord-006870-f5w6fw6q 5062 11 neurological neurological JJ cord-006870-f5w6fw6q 5062 12 morbidity morbidity NN cord-006870-f5w6fw6q 5062 13 and and CC cord-006870-f5w6fw6q 5062 14 mortality mortality NN cord-006870-f5w6fw6q 5062 15 with with IN cord-006870-f5w6fw6q 5062 16 few few JJ cord-006870-f5w6fw6q 5062 17 interventions intervention NNS cord-006870-f5w6fw6q 5062 18 to to TO cord-006870-f5w6fw6q 5062 19 prevent prevent VB cord-006870-f5w6fw6q 5062 20 delayed delay VBN cord-006870-f5w6fw6q 5062 21 cerebral cerebral JJ cord-006870-f5w6fw6q 5062 22 ischemia ischemia NN cord-006870-f5w6fw6q 5062 23 . . . cord-006870-f5w6fw6q 5063 1 Hypocapnia Hypocapnia NNP cord-006870-f5w6fw6q 5063 2 has have VBZ cord-006870-f5w6fw6q 5063 3 been be VBN cord-006870-f5w6fw6q 5063 4 associated associate VBN cord-006870-f5w6fw6q 5063 5 with with IN cord-006870-f5w6fw6q 5063 6 worse bad JJR cord-006870-f5w6fw6q 5063 7 outcomes outcome NNS cord-006870-f5w6fw6q 5063 8 in in IN cord-006870-f5w6fw6q 5063 9 brain brain NN cord-006870-f5w6fw6q 5063 10 injury injury NN cord-006870-f5w6fw6q 5063 11 . . . cord-006870-f5w6fw6q 5064 1 SAH SAH NNP cord-006870-f5w6fw6q 5064 2 patients patient NNS cord-006870-f5w6fw6q 5064 3 may may MD cord-006870-f5w6fw6q 5064 4 be be VB cord-006870-f5w6fw6q 5064 5 particularly particularly RB cord-006870-f5w6fw6q 5064 6 susceptible susceptible JJ cord-006870-f5w6fw6q 5064 7 to to IN cord-006870-f5w6fw6q 5064 8 hypocapnia hypocapnia NNP cord-006870-f5w6fw6q 5064 9 induced induce VBN cord-006870-f5w6fw6q 5064 10 vasoconstriction vasoconstriction NN cord-006870-f5w6fw6q 5064 11 . . . cord-006870-f5w6fw6q 5065 1 This this DT cord-006870-f5w6fw6q 5065 2 study study NN cord-006870-f5w6fw6q 5065 3 aims aim VBZ cord-006870-f5w6fw6q 5065 4 to to TO cord-006870-f5w6fw6q 5065 5 describe describe VB cord-006870-f5w6fw6q 5065 6 the the DT cord-006870-f5w6fw6q 5065 7 incidence incidence NN cord-006870-f5w6fw6q 5065 8 of of IN cord-006870-f5w6fw6q 5065 9 iatrogenic iatrogenic JJ cord-006870-f5w6fw6q 5065 10 and and CC cord-006870-f5w6fw6q 5065 11 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5065 12 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 5065 13 in in IN cord-006870-f5w6fw6q 5065 14 SAH SAH NNP cord-006870-f5w6fw6q 5065 15 patients patient NNS cord-006870-f5w6fw6q 5065 16 . . . cord-006870-f5w6fw6q 5066 1 A a DT cord-006870-f5w6fw6q 5066 2 descriptive descriptive JJ cord-006870-f5w6fw6q 5066 3 analysis analysis NN cord-006870-f5w6fw6q 5066 4 was be VBD cord-006870-f5w6fw6q 5066 5 performed perform VBN cord-006870-f5w6fw6q 5066 6 on on IN cord-006870-f5w6fw6q 5066 7 a a DT cord-006870-f5w6fw6q 5066 8 retrospective retrospective JJ cord-006870-f5w6fw6q 5066 9 cohort cohort NN cord-006870-f5w6fw6q 5066 10 of of IN cord-006870-f5w6fw6q 5066 11 adult adult NN cord-006870-f5w6fw6q 5066 12 SAH SAH NNP cord-006870-f5w6fw6q 5066 13 patients patient NNS cord-006870-f5w6fw6q 5066 14 admitted admit VBD cord-006870-f5w6fw6q 5066 15 to to IN cord-006870-f5w6fw6q 5066 16 Beth Beth NNP cord-006870-f5w6fw6q 5066 17 Israel Israel NNP cord-006870-f5w6fw6q 5066 18 Deaconess Deaconess NNP cord-006870-f5w6fw6q 5066 19 Medical Medical NNP cord-006870-f5w6fw6q 5066 20 Center Center NNP cord-006870-f5w6fw6q 5066 21 ICUs icus NN cord-006870-f5w6fw6q 5066 22 between between IN cord-006870-f5w6fw6q 5066 23 2008 2008 CD cord-006870-f5w6fw6q 5066 24 and and CC cord-006870-f5w6fw6q 5066 25 2015 2015 CD cord-006870-f5w6fw6q 5066 26 with with IN cord-006870-f5w6fw6q 5066 27 GCS GCS NNP cord-006870-f5w6fw6q 5066 28 < < XX cord-006870-f5w6fw6q 5066 29 9 9 CD cord-006870-f5w6fw6q 5066 30 who who WP cord-006870-f5w6fw6q 5066 31 were be VBD cord-006870-f5w6fw6q 5066 32 treated treat VBN cord-006870-f5w6fw6q 5066 33 with with IN cord-006870-f5w6fw6q 5066 34 mechanical mechanical JJ cord-006870-f5w6fw6q 5066 35 ventilation ventilation NN cord-006870-f5w6fw6q 5066 36 and and CC cord-006870-f5w6fw6q 5066 37 an an DT cord-006870-f5w6fw6q 5066 38 extraventricular extraventricular JJ cord-006870-f5w6fw6q 5066 39 drain drain NN cord-006870-f5w6fw6q 5066 40 , , , cord-006870-f5w6fw6q 5066 41 and and CC cord-006870-f5w6fw6q 5066 42 had have VBD cord-006870-f5w6fw6q 5066 43 at at RB cord-006870-f5w6fw6q 5066 44 least least RBS cord-006870-f5w6fw6q 5066 45 one one CD cord-006870-f5w6fw6q 5066 46 ABG ABG NNP cord-006870-f5w6fw6q 5066 47 . . . cord-006870-f5w6fw6q 5067 1 Patients patient NNS cord-006870-f5w6fw6q 5067 2 on on IN cord-006870-f5w6fw6q 5067 3 chronic chronic JJ cord-006870-f5w6fw6q 5067 4 ventilator ventilator NN cord-006870-f5w6fw6q 5067 5 support support NN cord-006870-f5w6fw6q 5067 6 were be VBD cord-006870-f5w6fw6q 5067 7 excluded exclude VBN cord-006870-f5w6fw6q 5067 8 . . . cord-006870-f5w6fw6q 5068 1 The the DT cord-006870-f5w6fw6q 5068 2 lowest low JJS cord-006870-f5w6fw6q 5068 3 PaCO2 PaCO2 NNP cord-006870-f5w6fw6q 5068 4 per per IN cord-006870-f5w6fw6q 5068 5 ICU ICU NNP cord-006870-f5w6fw6q 5068 6 day day NN cord-006870-f5w6fw6q 5068 7 was be VBD cord-006870-f5w6fw6q 5068 8 analyzed analyze VBN cord-006870-f5w6fw6q 5068 9 . . . cord-006870-f5w6fw6q 5069 1 125 125 CD cord-006870-f5w6fw6q 5069 2 patients patient NNS cord-006870-f5w6fw6q 5069 3 were be VBD cord-006870-f5w6fw6q 5069 4 included include VBN cord-006870-f5w6fw6q 5069 5 with with IN cord-006870-f5w6fw6q 5069 6 959 959 CD cord-006870-f5w6fw6q 5069 7 days day NNS cord-006870-f5w6fw6q 5069 8 with with IN cord-006870-f5w6fw6q 5069 9 at at RB cord-006870-f5w6fw6q 5069 10 least least RBS cord-006870-f5w6fw6q 5069 11 one one CD cord-006870-f5w6fw6q 5069 12 documented document VBN cord-006870-f5w6fw6q 5069 13 PaCO2 PaCO2 NNP cord-006870-f5w6fw6q 5069 14 . . . cord-006870-f5w6fw6q 5070 1 Mean Mean NNP cord-006870-f5w6fw6q 5070 2 GCS GCS NNP cord-006870-f5w6fw6q 5070 3 on on IN cord-006870-f5w6fw6q 5070 4 admission admission NN cord-006870-f5w6fw6q 5070 5 was be VBD cord-006870-f5w6fw6q 5070 6 5.0 5.0 CD cord-006870-f5w6fw6q 5070 7 ( ( -LRB- cord-006870-f5w6fw6q 5070 8 SD SD NNP cord-006870-f5w6fw6q 5070 9 1.7 1.7 CD cord-006870-f5w6fw6q 5070 10 ) ) -RRB- cord-006870-f5w6fw6q 5070 11 . . . cord-006870-f5w6fw6q 5071 1 70.3 70.3 CD cord-006870-f5w6fw6q 5071 2 % % NN cord-006870-f5w6fw6q 5071 3 of of IN cord-006870-f5w6fw6q 5071 4 patients patient NNS cord-006870-f5w6fw6q 5071 5 survived survive VBN cord-006870-f5w6fw6q 5071 6 to to IN cord-006870-f5w6fw6q 5071 7 hospital hospital NN cord-006870-f5w6fw6q 5071 8 discharge discharge NN cord-006870-f5w6fw6q 5071 9 . . . cord-006870-f5w6fw6q 5072 1 61.6 61.6 CD cord-006870-f5w6fw6q 5072 2 % % NN cord-006870-f5w6fw6q 5072 3 of of IN cord-006870-f5w6fw6q 5072 4 patients patient NNS cord-006870-f5w6fw6q 5072 5 were be VBD cord-006870-f5w6fw6q 5072 6 exposed expose VBN cord-006870-f5w6fw6q 5072 7 to to IN cord-006870-f5w6fw6q 5072 8 severe severe JJ cord-006870-f5w6fw6q 5072 9 hypocapnia hypocapnia NNP cord-006870-f5w6fw6q 5072 10 ( ( -LRB- cord-006870-f5w6fw6q 5073 1 PaCO2 PaCO2 NNP cord-006870-f5w6fw6q 5073 2 30mmHg 30mmhg CD cord-006870-f5w6fw6q 5073 3 , , , cord-006870-f5w6fw6q 5073 4 those those DT cord-006870-f5w6fw6q 5073 5 with with IN cord-006870-f5w6fw6q 5073 6 severe severe JJ cord-006870-f5w6fw6q 5073 7 hypocapnia hypocapnia NNP cord-006870-f5w6fw6q 5073 8 had have VBD cord-006870-f5w6fw6q 5073 9 similar similar JJ cord-006870-f5w6fw6q 5073 10 PaO2 PaO2 NNS cord-006870-f5w6fw6q 5073 11 and and CC cord-006870-f5w6fw6q 5073 12 PaO2 PaO2 NNS cord-006870-f5w6fw6q 5073 13 / / SYM cord-006870-f5w6fw6q 5073 14 FiO2 FiO2 NNS cord-006870-f5w6fw6q 5073 15 ratios ratio NNS cord-006870-f5w6fw6q 5073 16 , , , cord-006870-f5w6fw6q 5073 17 but but CC cord-006870-f5w6fw6q 5073 18 mildly mildly RB cord-006870-f5w6fw6q 5073 19 increased increase VBN cord-006870-f5w6fw6q 5073 20 leukocytosis leukocytosis NN cord-006870-f5w6fw6q 5073 21 ( ( -LRB- cord-006870-f5w6fw6q 5073 22 13.1 13.1 CD cord-006870-f5w6fw6q 5073 23 vs vs IN cord-006870-f5w6fw6q 5073 24 12.3 12.3 CD cord-006870-f5w6fw6q 5073 25 ) ) -RRB- cord-006870-f5w6fw6q 5073 26 . . . cord-006870-f5w6fw6q 5074 1 40.9 40.9 CD cord-006870-f5w6fw6q 5074 2 % % NN cord-006870-f5w6fw6q 5074 3 of of IN cord-006870-f5w6fw6q 5074 4 PaCO2s paco2 NNS cord-006870-f5w6fw6q 5074 5 < < XX cord-006870-f5w6fw6q 5074 6 30mmHg 30mmhg CD cord-006870-f5w6fw6q 5074 7 occurred occur VBD cord-006870-f5w6fw6q 5074 8 during during IN cord-006870-f5w6fw6q 5074 9 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5074 10 ventilation ventilation NN cord-006870-f5w6fw6q 5074 11 or or CC cord-006870-f5w6fw6q 5074 12 over over IN cord-006870-f5w6fw6q 5074 13 - - HYPH cord-006870-f5w6fw6q 5074 14 breathing breathing NN cord-006870-f5w6fw6q 5074 15 . . . cord-006870-f5w6fw6q 5075 1 Prior prior JJ cord-006870-f5w6fw6q 5075 2 studies study NNS cord-006870-f5w6fw6q 5075 3 have have VBP cord-006870-f5w6fw6q 5075 4 shown show VBN cord-006870-f5w6fw6q 5075 5 that that IN cord-006870-f5w6fw6q 5075 6 hypocapnia hypocapnia NNP cord-006870-f5w6fw6q 5075 7 causes cause VBZ cord-006870-f5w6fw6q 5075 8 decreased decrease VBD cord-006870-f5w6fw6q 5075 9 brain brain NN cord-006870-f5w6fw6q 5075 10 tissue tissue NN cord-006870-f5w6fw6q 5075 11 perfusion perfusion NN cord-006870-f5w6fw6q 5075 12 and and CC cord-006870-f5w6fw6q 5075 13 is be VBZ cord-006870-f5w6fw6q 5075 14 associated associate VBN cord-006870-f5w6fw6q 5075 15 with with IN cord-006870-f5w6fw6q 5075 16 worse bad JJR cord-006870-f5w6fw6q 5075 17 outcomes outcome NNS cord-006870-f5w6fw6q 5075 18 in in IN cord-006870-f5w6fw6q 5075 19 SAH SAH NNP cord-006870-f5w6fw6q 5075 20 patients patient NNS cord-006870-f5w6fw6q 5075 21 . . . cord-006870-f5w6fw6q 5076 1 These these DT cord-006870-f5w6fw6q 5076 2 recent recent JJ cord-006870-f5w6fw6q 5076 3 data datum NNS cord-006870-f5w6fw6q 5076 4 demonstrate demonstrate VBP cord-006870-f5w6fw6q 5076 5 that that IN cord-006870-f5w6fw6q 5076 6 severe severe JJ cord-006870-f5w6fw6q 5076 7 hypocapnia hypocapnia NNP cord-006870-f5w6fw6q 5076 8 is be VBZ cord-006870-f5w6fw6q 5076 9 common common JJ cord-006870-f5w6fw6q 5076 10 in in IN cord-006870-f5w6fw6q 5076 11 patients patient NNS cord-006870-f5w6fw6q 5076 12 with with IN cord-006870-f5w6fw6q 5076 13 SAH SAH NNP cord-006870-f5w6fw6q 5076 14 severe severe JJ cord-006870-f5w6fw6q 5076 15 enough enough RB cord-006870-f5w6fw6q 5076 16 to to TO cord-006870-f5w6fw6q 5076 17 warrant warrant VB cord-006870-f5w6fw6q 5076 18 intubation intubation NN cord-006870-f5w6fw6q 5076 19 , , , cord-006870-f5w6fw6q 5076 20 and and CC cord-006870-f5w6fw6q 5076 21 is be VBZ cord-006870-f5w6fw6q 5076 22 associated associate VBN cord-006870-f5w6fw6q 5076 23 with with IN cord-006870-f5w6fw6q 5076 24 both both CC cord-006870-f5w6fw6q 5076 25 iatrogenic iatrogenic JJ cord-006870-f5w6fw6q 5076 26 and and CC cord-006870-f5w6fw6q 5076 27 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5076 28 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 5076 29 . . . cord-006870-f5w6fw6q 5077 1 Hypocapnia Hypocapnia NNP cord-006870-f5w6fw6q 5077 2 is be VBZ cord-006870-f5w6fw6q 5077 3 not not RB cord-006870-f5w6fw6q 5077 4 primarily primarily RB cord-006870-f5w6fw6q 5077 5 compensatory compensatory JJ cord-006870-f5w6fw6q 5077 6 or or CC cord-006870-f5w6fw6q 5077 7 hypoxia hypoxia NN cord-006870-f5w6fw6q 5077 8 driven drive VBN cord-006870-f5w6fw6q 5077 9 , , , cord-006870-f5w6fw6q 5077 10 as as IN cord-006870-f5w6fw6q 5077 11 suggested suggest VBN cord-006870-f5w6fw6q 5077 12 by by IN cord-006870-f5w6fw6q 5077 13 mean mean JJ cord-006870-f5w6fw6q 5077 14 pH pH NNP cord-006870-f5w6fw6q 5077 15 and and CC cord-006870-f5w6fw6q 5077 16 PaO2 pao2 NN cord-006870-f5w6fw6q 5077 17 . . . cord-006870-f5w6fw6q 5078 1 Confirmation confirmation NN cord-006870-f5w6fw6q 5078 2 of of IN cord-006870-f5w6fw6q 5078 3 this this DT cord-006870-f5w6fw6q 5078 4 association association NN cord-006870-f5w6fw6q 5078 5 and and CC cord-006870-f5w6fw6q 5078 6 potential potential JJ cord-006870-f5w6fw6q 5078 7 future future JJ cord-006870-f5w6fw6q 5078 8 interventions intervention NNS cord-006870-f5w6fw6q 5078 9 require require VBP cord-006870-f5w6fw6q 5078 10 further further JJ cord-006870-f5w6fw6q 5078 11 study study NN cord-006870-f5w6fw6q 5078 12 . . . cord-006870-f5w6fw6q 5079 1 Although although IN cord-006870-f5w6fw6q 5079 2 delirium delirium NN cord-006870-f5w6fw6q 5079 3 is be VBZ cord-006870-f5w6fw6q 5079 4 associated associate VBN cord-006870-f5w6fw6q 5079 5 with with IN cord-006870-f5w6fw6q 5079 6 higher high JJR cord-006870-f5w6fw6q 5079 7 rates rate NNS cord-006870-f5w6fw6q 5079 8 of of IN cord-006870-f5w6fw6q 5079 9 hospital hospital NN cord-006870-f5w6fw6q 5079 10 complications complication NNS cord-006870-f5w6fw6q 5079 11 among among IN cord-006870-f5w6fw6q 5079 12 critical critical JJ cord-006870-f5w6fw6q 5079 13 care care NN cord-006870-f5w6fw6q 5079 14 patients patient NNS cord-006870-f5w6fw6q 5079 15 , , , cord-006870-f5w6fw6q 5079 16 limited limited JJ cord-006870-f5w6fw6q 5079 17 data datum NNS cord-006870-f5w6fw6q 5079 18 exist exist VBP cord-006870-f5w6fw6q 5079 19 on on IN cord-006870-f5w6fw6q 5079 20 risk risk NN cord-006870-f5w6fw6q 5079 21 factors factor NNS cord-006870-f5w6fw6q 5079 22 for for IN cord-006870-f5w6fw6q 5079 23 delirium delirium NN cord-006870-f5w6fw6q 5079 24 in in IN cord-006870-f5w6fw6q 5079 25 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5079 26 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5079 27 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5079 28 ( ( -LRB- cord-006870-f5w6fw6q 5079 29 SAH SAH NNP cord-006870-f5w6fw6q 5079 30 ) ) -RRB- cord-006870-f5w6fw6q 5079 31 . . . cord-006870-f5w6fw6q 5080 1 A a DT cord-006870-f5w6fw6q 5080 2 previous previous JJ cord-006870-f5w6fw6q 5080 3 study study NN cord-006870-f5w6fw6q 5080 4 identified identify VBD cord-006870-f5w6fw6q 5080 5 older old JJR cord-006870-f5w6fw6q 5080 6 age age NN cord-006870-f5w6fw6q 5080 7 , , , cord-006870-f5w6fw6q 5080 8 high high JJ cord-006870-f5w6fw6q 5080 9 Hunt Hunt NNP cord-006870-f5w6fw6q 5080 10 Hess Hess NNP cord-006870-f5w6fw6q 5080 11 grade grade NN cord-006870-f5w6fw6q 5080 12 , , , cord-006870-f5w6fw6q 5080 13 intraventricular intraventricular JJ cord-006870-f5w6fw6q 5080 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5080 15 ( ( -LRB- cord-006870-f5w6fw6q 5080 16 IVH IVH NNP cord-006870-f5w6fw6q 5080 17 ) ) -RRB- cord-006870-f5w6fw6q 5080 18 , , , cord-006870-f5w6fw6q 5080 19 and and CC cord-006870-f5w6fw6q 5080 20 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5080 21 as as IN cord-006870-f5w6fw6q 5080 22 risk risk NN cord-006870-f5w6fw6q 5080 23 factors factor NNS cord-006870-f5w6fw6q 5080 24 for for IN cord-006870-f5w6fw6q 5080 25 delirium delirium NN cord-006870-f5w6fw6q 5080 26 . . . cord-006870-f5w6fw6q 5081 1 We -PRON- PRP cord-006870-f5w6fw6q 5081 2 sought seek VBD cord-006870-f5w6fw6q 5081 3 to to TO cord-006870-f5w6fw6q 5081 4 identify identify VB cord-006870-f5w6fw6q 5081 5 risk risk NN cord-006870-f5w6fw6q 5081 6 factors factor NNS cord-006870-f5w6fw6q 5081 7 for for IN cord-006870-f5w6fw6q 5081 8 delirium delirium NN cord-006870-f5w6fw6q 5081 9 during during IN cord-006870-f5w6fw6q 5081 10 admission admission NN cord-006870-f5w6fw6q 5081 11 after after IN cord-006870-f5w6fw6q 5081 12 SAH SAH NNP cord-006870-f5w6fw6q 5081 13 . . . cord-006870-f5w6fw6q 5082 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 5082 2 review review NN cord-006870-f5w6fw6q 5082 3 was be VBD cord-006870-f5w6fw6q 5082 4 performed perform VBN cord-006870-f5w6fw6q 5082 5 of of IN cord-006870-f5w6fw6q 5082 6 prospectively prospectively RB cord-006870-f5w6fw6q 5082 7 collected collect VBN cord-006870-f5w6fw6q 5082 8 data datum NNS cord-006870-f5w6fw6q 5082 9 for for IN cord-006870-f5w6fw6q 5082 10 consecutive consecutive JJ cord-006870-f5w6fw6q 5082 11 SAH SAH NNP cord-006870-f5w6fw6q 5082 12 patients patient NNS cord-006870-f5w6fw6q 5082 13 enrolled enrol VBD cord-006870-f5w6fw6q 5082 14 into into IN cord-006870-f5w6fw6q 5082 15 the the DT cord-006870-f5w6fw6q 5082 16 University University NNP cord-006870-f5w6fw6q 5082 17 of of IN cord-006870-f5w6fw6q 5082 18 Maryland Maryland NNP cord-006870-f5w6fw6q 5082 19 Recovery Recovery NNP cord-006870-f5w6fw6q 5082 20 After after IN cord-006870-f5w6fw6q 5082 21 Cerebral Cerebral NNP cord-006870-f5w6fw6q 5082 22 Hemorrhage Hemorrhage NNP cord-006870-f5w6fw6q 5082 23 ( ( -LRB- cord-006870-f5w6fw6q 5082 24 REACH reach VB cord-006870-f5w6fw6q 5082 25 ) ) -RRB- cord-006870-f5w6fw6q 5082 26 Study study NN cord-006870-f5w6fw6q 5082 27 . . . cord-006870-f5w6fw6q 5083 1 Baseline baseline JJ cord-006870-f5w6fw6q 5083 2 data datum NNS cord-006870-f5w6fw6q 5083 3 and and CC cord-006870-f5w6fw6q 5083 4 clinical clinical JJ cord-006870-f5w6fw6q 5083 5 complications complication NNS cord-006870-f5w6fw6q 5083 6 during during IN cord-006870-f5w6fw6q 5083 7 each each DT cord-006870-f5w6fw6q 5083 8 admission admission NN cord-006870-f5w6fw6q 5083 9 , , , cord-006870-f5w6fw6q 5083 10 including include VBG cord-006870-f5w6fw6q 5083 11 delirium delirium NN cord-006870-f5w6fw6q 5083 12 , , , cord-006870-f5w6fw6q 5083 13 were be VBD cord-006870-f5w6fw6q 5083 14 recorded record VBN cord-006870-f5w6fw6q 5083 15 . . . cord-006870-f5w6fw6q 5084 1 Statistical statistical JJ cord-006870-f5w6fw6q 5084 2 analysis analysis NN cord-006870-f5w6fw6q 5084 3 was be VBD cord-006870-f5w6fw6q 5084 4 performed perform VBN cord-006870-f5w6fw6q 5084 5 using use VBG cord-006870-f5w6fw6q 5084 6 univariate univariate JJ cord-006870-f5w6fw6q 5084 7 and and CC cord-006870-f5w6fw6q 5084 8 multivariate multivariate JJ cord-006870-f5w6fw6q 5084 9 logistical logistical JJ cord-006870-f5w6fw6q 5084 10 regression regression NN cord-006870-f5w6fw6q 5084 11 . . . cord-006870-f5w6fw6q 5085 1 103 103 CD cord-006870-f5w6fw6q 5086 1 SAH SAH NNP cord-006870-f5w6fw6q 5086 2 patients patient NNS cord-006870-f5w6fw6q 5086 3 from from IN cord-006870-f5w6fw6q 5086 4 July July NNP cord-006870-f5w6fw6q 5086 5 2014 2014 CD cord-006870-f5w6fw6q 5086 6 to to IN cord-006870-f5w6fw6q 5086 7 January January NNP cord-006870-f5w6fw6q 5086 8 2016 2016 CD cord-006870-f5w6fw6q 5086 9 were be VBD cord-006870-f5w6fw6q 5086 10 reviewed review VBN cord-006870-f5w6fw6q 5086 11 . . . cord-006870-f5w6fw6q 5087 1 While while IN cord-006870-f5w6fw6q 5087 2 age age NN cord-006870-f5w6fw6q 5087 3 was be VBD cord-006870-f5w6fw6q 5087 4 not not RB cord-006870-f5w6fw6q 5087 5 singly singly RB cord-006870-f5w6fw6q 5087 6 associated associate VBN cord-006870-f5w6fw6q 5087 7 with with IN cord-006870-f5w6fw6q 5087 8 delirium delirium NN cord-006870-f5w6fw6q 5087 9 during during IN cord-006870-f5w6fw6q 5087 10 ICU ICU NNP cord-006870-f5w6fw6q 5087 11 admission admission NN cord-006870-f5w6fw6q 5087 12 , , , cord-006870-f5w6fw6q 5087 13 higher high JJR cord-006870-f5w6fw6q 5087 14 Hunt Hunt NNP cord-006870-f5w6fw6q 5087 15 Hess Hess NNP cord-006870-f5w6fw6q 5087 16 grade grade NN cord-006870-f5w6fw6q 5087 17 , , , cord-006870-f5w6fw6q 5087 18 IVH IVH NNP cord-006870-f5w6fw6q 5087 19 , , , cord-006870-f5w6fw6q 5087 20 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5087 21 , , , cord-006870-f5w6fw6q 5087 22 hospital hospital NN cord-006870-f5w6fw6q 5087 23 - - HYPH cord-006870-f5w6fw6q 5087 24 acquired acquire VBN cord-006870-f5w6fw6q 5087 25 infection infection NN cord-006870-f5w6fw6q 5087 26 , , , cord-006870-f5w6fw6q 5087 27 elevated elevate VBN cord-006870-f5w6fw6q 5087 28 troponin troponin NN cord-006870-f5w6fw6q 5087 29 , , , cord-006870-f5w6fw6q 5087 30 and and CC cord-006870-f5w6fw6q 5087 31 intubation intubation NN cord-006870-f5w6fw6q 5087 32 were be VBD cord-006870-f5w6fw6q 5087 33 significantly significantly RB cord-006870-f5w6fw6q 5087 34 associated associate VBN cord-006870-f5w6fw6q 5087 35 with with IN cord-006870-f5w6fw6q 5087 36 delirium delirium NN cord-006870-f5w6fw6q 5087 37 on on IN cord-006870-f5w6fw6q 5087 38 univariate univariate JJ cord-006870-f5w6fw6q 5087 39 analyses analysis NNS cord-006870-f5w6fw6q 5087 40 . . . cord-006870-f5w6fw6q 5088 1 Upon upon IN cord-006870-f5w6fw6q 5088 2 stepwise stepwise JJ cord-006870-f5w6fw6q 5088 3 multivariate multivariate JJ cord-006870-f5w6fw6q 5088 4 logistic logistic JJ cord-006870-f5w6fw6q 5088 5 regression regression NN cord-006870-f5w6fw6q 5088 6 , , , cord-006870-f5w6fw6q 5088 7 IVH IVH NNP cord-006870-f5w6fw6q 5088 8 ( ( -LRB- cord-006870-f5w6fw6q 5088 9 OR or CC cord-006870-f5w6fw6q 5088 10 9.6 9.6 CD cord-006870-f5w6fw6q 5088 11 , , , cord-006870-f5w6fw6q 5088 12 p=0.04 p=0.04 NNP cord-006870-f5w6fw6q 5088 13 ) ) -RRB- cord-006870-f5w6fw6q 5088 14 and and CC cord-006870-f5w6fw6q 5088 15 intubation intubation NN cord-006870-f5w6fw6q 5088 16 ( ( -LRB- cord-006870-f5w6fw6q 5088 17 OR or CC cord-006870-f5w6fw6q 5088 18 6.4 6.4 CD cord-006870-f5w6fw6q 5088 19 , , , cord-006870-f5w6fw6q 5088 20 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 5088 21 ) ) -RRB- cord-006870-f5w6fw6q 5088 22 remained remain VBD cord-006870-f5w6fw6q 5088 23 significantly significantly RB cord-006870-f5w6fw6q 5088 24 associated associate VBN cord-006870-f5w6fw6q 5088 25 with with IN cord-006870-f5w6fw6q 5088 26 delirium delirium NN cord-006870-f5w6fw6q 5088 27 . . . cord-006870-f5w6fw6q 5089 1 IVH IVH NNP cord-006870-f5w6fw6q 5089 2 and and CC cord-006870-f5w6fw6q 5089 3 intubation intubation NN cord-006870-f5w6fw6q 5089 4 predicts predict VBZ cord-006870-f5w6fw6q 5089 5 delirium delirium NN cord-006870-f5w6fw6q 5089 6 during during IN cord-006870-f5w6fw6q 5089 7 ICU ICU NNP cord-006870-f5w6fw6q 5089 8 admission admission NN cord-006870-f5w6fw6q 5089 9 for for IN cord-006870-f5w6fw6q 5089 10 SAH SAH NNP cord-006870-f5w6fw6q 5089 11 . . . cord-006870-f5w6fw6q 5090 1 Further further JJ cord-006870-f5w6fw6q 5090 2 analyses analysis NNS cord-006870-f5w6fw6q 5090 3 are be VBP cord-006870-f5w6fw6q 5090 4 needed need VBN cord-006870-f5w6fw6q 5090 5 to to TO cord-006870-f5w6fw6q 5090 6 determine determine VB cord-006870-f5w6fw6q 5090 7 if if IN cord-006870-f5w6fw6q 5090 8 the the DT cord-006870-f5w6fw6q 5090 9 relationship relationship NN cord-006870-f5w6fw6q 5090 10 between between IN cord-006870-f5w6fw6q 5090 11 IVH IVH NNP cord-006870-f5w6fw6q 5090 12 and and CC cord-006870-f5w6fw6q 5090 13 delirium delirium NN cord-006870-f5w6fw6q 5090 14 is be VBZ cord-006870-f5w6fw6q 5090 15 primarily primarily RB cord-006870-f5w6fw6q 5090 16 explained explain VBN cord-006870-f5w6fw6q 5090 17 by by IN cord-006870-f5w6fw6q 5090 18 risk risk NN cord-006870-f5w6fw6q 5090 19 of of IN cord-006870-f5w6fw6q 5090 20 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5090 21 , , , cord-006870-f5w6fw6q 5090 22 risk risk NN cord-006870-f5w6fw6q 5090 23 of of IN cord-006870-f5w6fw6q 5090 24 fever fever NN cord-006870-f5w6fw6q 5090 25 , , , cord-006870-f5w6fw6q 5090 26 medication medication NN cord-006870-f5w6fw6q 5090 27 exposure exposure NN cord-006870-f5w6fw6q 5090 28 , , , cord-006870-f5w6fw6q 5090 29 or or CC cord-006870-f5w6fw6q 5090 30 through through IN cord-006870-f5w6fw6q 5090 31 independent independent JJ cord-006870-f5w6fw6q 5090 32 mechanisms mechanism NNS cord-006870-f5w6fw6q 5090 33 . . . cord-006870-f5w6fw6q 5091 1 Stroke stroke NN cord-006870-f5w6fw6q 5091 2 triage triage NN cord-006870-f5w6fw6q 5091 3 scales scale NNS cord-006870-f5w6fw6q 5091 4 are be VBP cord-006870-f5w6fw6q 5091 5 very very RB cord-006870-f5w6fw6q 5091 6 important important JJ cord-006870-f5w6fw6q 5091 7 in in IN cord-006870-f5w6fw6q 5091 8 order order NN cord-006870-f5w6fw6q 5091 9 to to TO cord-006870-f5w6fw6q 5091 10 expedite expedite VB cord-006870-f5w6fw6q 5091 11 acute acute JJ cord-006870-f5w6fw6q 5091 12 evaluation evaluation NN cord-006870-f5w6fw6q 5091 13 , , , cord-006870-f5w6fw6q 5091 14 assure assure VB cord-006870-f5w6fw6q 5091 15 quick quick JJ cord-006870-f5w6fw6q 5091 16 door door NN cord-006870-f5w6fw6q 5091 17 to to IN cord-006870-f5w6fw6q 5091 18 neuroimaging neuroimage VBG cord-006870-f5w6fw6q 5091 19 time time NN cord-006870-f5w6fw6q 5091 20 and and CC cord-006870-f5w6fw6q 5091 21 decrease decrease VB cord-006870-f5w6fw6q 5091 22 door door NN cord-006870-f5w6fw6q 5091 23 to to TO cord-006870-f5w6fw6q 5091 24 needle needle NN cord-006870-f5w6fw6q 5091 25 time time NN cord-006870-f5w6fw6q 5091 26 in in IN cord-006870-f5w6fw6q 5091 27 patients patient NNS cord-006870-f5w6fw6q 5091 28 with with IN cord-006870-f5w6fw6q 5091 29 ischemic ischemic JJ cord-006870-f5w6fw6q 5091 30 stroke stroke NN cord-006870-f5w6fw6q 5091 31 eligible eligible JJ cord-006870-f5w6fw6q 5091 32 to to IN cord-006870-f5w6fw6q 5091 33 intravenous intravenous JJ cord-006870-f5w6fw6q 5091 34 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 5091 35 . . . cord-006870-f5w6fw6q 5092 1 Subarachnoid subarachnoid IN cord-006870-f5w6fw6q 5092 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5092 3 ( ( -LRB- cord-006870-f5w6fw6q 5092 4 SAH SAH NNP cord-006870-f5w6fw6q 5092 5 ) ) -RRB- cord-006870-f5w6fw6q 5092 6 is be VBZ cord-006870-f5w6fw6q 5092 7 associated associate VBN cord-006870-f5w6fw6q 5092 8 with with IN cord-006870-f5w6fw6q 5092 9 a a DT cord-006870-f5w6fw6q 5092 10 high high JJ cord-006870-f5w6fw6q 5092 11 mortality mortality NN cord-006870-f5w6fw6q 5092 12 in in IN cord-006870-f5w6fw6q 5092 13 the the DT cord-006870-f5w6fw6q 5092 14 acute acute JJ cord-006870-f5w6fw6q 5092 15 phase phase NN cord-006870-f5w6fw6q 5092 16 due due IN cord-006870-f5w6fw6q 5092 17 to to IN cord-006870-f5w6fw6q 5092 18 a a DT cord-006870-f5w6fw6q 5092 19 particular particular JJ cord-006870-f5w6fw6q 5092 20 risk risk NN cord-006870-f5w6fw6q 5092 21 of of IN cord-006870-f5w6fw6q 5092 22 early early JJ cord-006870-f5w6fw6q 5092 23 and and CC cord-006870-f5w6fw6q 5092 24 devastating devastating JJ cord-006870-f5w6fw6q 5092 25 re re NN cord-006870-f5w6fw6q 5092 26 - - NN cord-006870-f5w6fw6q 5092 27 bleeding bleeding NN cord-006870-f5w6fw6q 5092 28 . . . cord-006870-f5w6fw6q 5093 1 Therefore therefore RB cord-006870-f5w6fw6q 5093 2 patients patient NNS cord-006870-f5w6fw6q 5093 3 with with IN cord-006870-f5w6fw6q 5093 4 SAH SAH NNP cord-006870-f5w6fw6q 5093 5 also also RB cord-006870-f5w6fw6q 5093 6 need need VBP cord-006870-f5w6fw6q 5093 7 urgent urgent JJ cord-006870-f5w6fw6q 5093 8 assessment assessment NN cord-006870-f5w6fw6q 5093 9 . . . cord-006870-f5w6fw6q 5094 1 The the DT cord-006870-f5w6fw6q 5094 2 performance performance NN cord-006870-f5w6fw6q 5094 3 of of IN cord-006870-f5w6fw6q 5094 4 classic classic JJ cord-006870-f5w6fw6q 5094 5 triage triage NN cord-006870-f5w6fw6q 5094 6 stroke stroke NN cord-006870-f5w6fw6q 5094 7 scales scale NNS cord-006870-f5w6fw6q 5094 8 in in IN cord-006870-f5w6fw6q 5094 9 the the DT cord-006870-f5w6fw6q 5094 10 identification identification NN cord-006870-f5w6fw6q 5094 11 of of IN cord-006870-f5w6fw6q 5094 12 patients patient NNS cord-006870-f5w6fw6q 5094 13 with with IN cord-006870-f5w6fw6q 5094 14 SAH SAH NNP cord-006870-f5w6fw6q 5094 15 was be VBD cord-006870-f5w6fw6q 5094 16 not not RB cord-006870-f5w6fw6q 5094 17 previously previously RB cord-006870-f5w6fw6q 5094 18 evaluated evaluate VBN cord-006870-f5w6fw6q 5094 19 . . . cord-006870-f5w6fw6q 5095 1 The the DT cord-006870-f5w6fw6q 5095 2 objective objective NN cord-006870-f5w6fw6q 5095 3 of of IN cord-006870-f5w6fw6q 5095 4 our -PRON- PRP$ cord-006870-f5w6fw6q 5095 5 work work NN cord-006870-f5w6fw6q 5095 6 was be VBD cord-006870-f5w6fw6q 5095 7 to to TO cord-006870-f5w6fw6q 5095 8 evaluate evaluate VB cord-006870-f5w6fw6q 5095 9 the the DT cord-006870-f5w6fw6q 5095 10 performance performance NN cord-006870-f5w6fw6q 5095 11 of of IN cord-006870-f5w6fw6q 5095 12 the the DT cord-006870-f5w6fw6q 5095 13 Los Los NNP cord-006870-f5w6fw6q 5095 14 Angeles Angeles NNP cord-006870-f5w6fw6q 5095 15 Prehospital Prehospital NNP cord-006870-f5w6fw6q 5095 16 Stroke Stroke NNP cord-006870-f5w6fw6q 5095 17 Screen Screen NNP cord-006870-f5w6fw6q 5095 18 ( ( -LRB- cord-006870-f5w6fw6q 5095 19 LAPSS LAPSS NNP cord-006870-f5w6fw6q 5095 20 ) ) -RRB- cord-006870-f5w6fw6q 5095 21 in in IN cord-006870-f5w6fw6q 5095 22 identifying identify VBG cord-006870-f5w6fw6q 5095 23 patients patient NNS cord-006870-f5w6fw6q 5095 24 with with IN cord-006870-f5w6fw6q 5095 25 SAH SAH NNP cord-006870-f5w6fw6q 5095 26 admitted admit VBD cord-006870-f5w6fw6q 5095 27 to to IN cord-006870-f5w6fw6q 5095 28 a a DT cord-006870-f5w6fw6q 5095 29 tertiary tertiary JJ cord-006870-f5w6fw6q 5095 30 hospital hospital NN cord-006870-f5w6fw6q 5095 31 . . . cord-006870-f5w6fw6q 5096 1 We -PRON- PRP cord-006870-f5w6fw6q 5096 2 evaluated evaluate VBD cord-006870-f5w6fw6q 5096 3 consecutive consecutive JJ cord-006870-f5w6fw6q 5096 4 patients patient NNS cord-006870-f5w6fw6q 5096 5 admitted admit VBN cord-006870-f5w6fw6q 5096 6 to to IN cord-006870-f5w6fw6q 5096 7 a a DT cord-006870-f5w6fw6q 5096 8 tertiary tertiary JJ cord-006870-f5w6fw6q 5096 9 hospital hospital NN cord-006870-f5w6fw6q 5096 10 with with IN cord-006870-f5w6fw6q 5096 11 SAH SAH NNP cord-006870-f5w6fw6q 5096 12 from from IN cord-006870-f5w6fw6q 5096 13 January January NNP cord-006870-f5w6fw6q 5096 14 2009 2009 CD cord-006870-f5w6fw6q 5096 15 to to IN cord-006870-f5w6fw6q 5096 16 May May NNP cord-006870-f5w6fw6q 5096 17 2016 2016 CD cord-006870-f5w6fw6q 5096 18 . . . cord-006870-f5w6fw6q 5097 1 At at IN cord-006870-f5w6fw6q 5097 2 hospital hospital NN cord-006870-f5w6fw6q 5097 3 admission admission NN cord-006870-f5w6fw6q 5097 4 , , , cord-006870-f5w6fw6q 5097 5 LAPSS LAPSS NNP cord-006870-f5w6fw6q 5097 6 was be VBD cord-006870-f5w6fw6q 5097 7 applied apply VBN cord-006870-f5w6fw6q 5097 8 by by IN cord-006870-f5w6fw6q 5097 9 trained trained JJ cord-006870-f5w6fw6q 5097 10 nurse nurse NN cord-006870-f5w6fw6q 5097 11 personnel personnel NNS cord-006870-f5w6fw6q 5097 12 to to IN cord-006870-f5w6fw6q 5097 13 all all DT cord-006870-f5w6fw6q 5097 14 noncomatose noncomatose JJ cord-006870-f5w6fw6q 5097 15 patients patient NNS cord-006870-f5w6fw6q 5097 16 with with IN cord-006870-f5w6fw6q 5097 17 complaints complaint NNS cord-006870-f5w6fw6q 5097 18 suggestive suggestive JJ cord-006870-f5w6fw6q 5097 19 of of IN cord-006870-f5w6fw6q 5097 20 neurological neurological JJ cord-006870-f5w6fw6q 5097 21 disease disease NN cord-006870-f5w6fw6q 5097 22 . . . cord-006870-f5w6fw6q 5098 1 A a DT cord-006870-f5w6fw6q 5098 2 total total NN cord-006870-f5w6fw6q 5098 3 of of IN cord-006870-f5w6fw6q 5098 4 139 139 CD cord-006870-f5w6fw6q 5098 5 with with IN cord-006870-f5w6fw6q 5098 6 SAH SAH NNP cord-006870-f5w6fw6q 5098 7 patients patient NNS cord-006870-f5w6fw6q 5098 8 were be VBD cord-006870-f5w6fw6q 5098 9 evaluated evaluate VBN cord-006870-f5w6fw6q 5098 10 ( ( -LRB- cord-006870-f5w6fw6q 5098 11 mean mean UH cord-006870-f5w6fw6q 5098 12 age age NN cord-006870-f5w6fw6q 5098 13 55.9 55.9 CD cord-006870-f5w6fw6q 5098 14 + + CC cord-006870-f5w6fw6q 5098 15 /-15.6 /-15.6 NN cord-006870-f5w6fw6q 5098 16 ) ) -RRB- cord-006870-f5w6fw6q 5098 17 , , , cord-006870-f5w6fw6q 5098 18 59.7 59.7 CD cord-006870-f5w6fw6q 5098 19 % % NN cord-006870-f5w6fw6q 5098 20 females female NNS cord-006870-f5w6fw6q 5098 21 ) ) -RRB- cord-006870-f5w6fw6q 5098 22 . . . cord-006870-f5w6fw6q 5099 1 LAPSS LAPSS NNP cord-006870-f5w6fw6q 5099 2 was be VBD cord-006870-f5w6fw6q 5099 3 applied apply VBN cord-006870-f5w6fw6q 5099 4 to to IN cord-006870-f5w6fw6q 5099 5 94 94 CD cord-006870-f5w6fw6q 5099 6 patients patient NNS cord-006870-f5w6fw6q 5099 7 . . . cord-006870-f5w6fw6q 5100 1 LAPSS LAPSS NNP cord-006870-f5w6fw6q 5100 2 was be VBD cord-006870-f5w6fw6q 5100 3 positive positive JJ cord-006870-f5w6fw6q 5100 4 in in IN cord-006870-f5w6fw6q 5100 5 only only RB cord-006870-f5w6fw6q 5100 6 45 45 CD cord-006870-f5w6fw6q 5100 7 patients patient NNS cord-006870-f5w6fw6q 5100 8 ( ( -LRB- cord-006870-f5w6fw6q 5100 9 32.4 32.4 CD cord-006870-f5w6fw6q 5100 10 % % NN cord-006870-f5w6fw6q 5100 11 ) ) -RRB- cord-006870-f5w6fw6q 5100 12 . . . cord-006870-f5w6fw6q 5101 1 Patients patient NNS cord-006870-f5w6fw6q 5101 2 with with IN cord-006870-f5w6fw6q 5101 3 a a DT cord-006870-f5w6fw6q 5101 4 positive positive JJ cord-006870-f5w6fw6q 5101 5 LAPSS LAPSS NNP cord-006870-f5w6fw6q 5101 6 had have VBD cord-006870-f5w6fw6q 5101 7 higher high JJR cord-006870-f5w6fw6q 5101 8 NIHSS NIHSS NNP cord-006870-f5w6fw6q 5101 9 stroke stroke NN cord-006870-f5w6fw6q 5101 10 score score NN cord-006870-f5w6fw6q 5101 11 at at IN cord-006870-f5w6fw6q 5101 12 admission admission NN cord-006870-f5w6fw6q 5101 13 ( ( -LRB- cord-006870-f5w6fw6q 5101 14 4 4 CD cord-006870-f5w6fw6q 5101 15 , , , cord-006870-f5w6fw6q 5101 16 [ [ -LRB- cord-006870-f5w6fw6q 5101 17 2,23 2,23 CD cord-006870-f5w6fw6q 5101 18 ] ] -RRB- cord-006870-f5w6fw6q 5101 19 versus versus IN cord-006870-f5w6fw6q 5101 20 0 0 CD cord-006870-f5w6fw6q 5101 21 , , , cord-006870-f5w6fw6q 5101 22 p<0.01 p<0.01 NNP cord-006870-f5w6fw6q 5101 23 ) ) -RRB- cord-006870-f5w6fw6q 5101 24 , , , cord-006870-f5w6fw6q 5101 25 lower low JJR cord-006870-f5w6fw6q 5101 26 Glasgow Glasgow NNP cord-006870-f5w6fw6q 5101 27 coma coma NN cord-006870-f5w6fw6q 5101 28 Scores score NNS cord-006870-f5w6fw6q 5101 29 ( ( -LRB- cord-006870-f5w6fw6q 5101 30 14 14 CD cord-006870-f5w6fw6q 5101 31 [ [ -LRB- cord-006870-f5w6fw6q 5101 32 8 8 CD cord-006870-f5w6fw6q 5101 33 , , , cord-006870-f5w6fw6q 5101 34 15 15 CD cord-006870-f5w6fw6q 5101 35 ] ] -RRB- cord-006870-f5w6fw6q 5101 36 versus versus IN cord-006870-f5w6fw6q 5101 37 15 15 CD cord-006870-f5w6fw6q 5101 38 , , , cord-006870-f5w6fw6q 5101 39 p<0.01 p<0.01 NNP cord-006870-f5w6fw6q 5101 40 ) ) -RRB- cord-006870-f5w6fw6q 5101 41 and and CC cord-006870-f5w6fw6q 5101 42 a a DT cord-006870-f5w6fw6q 5101 43 significant significant JJ cord-006870-f5w6fw6q 5101 44 shorter short JJR cord-006870-f5w6fw6q 5101 45 door door NN cord-006870-f5w6fw6q 5101 46 to to IN cord-006870-f5w6fw6q 5101 47 neuroimaging neuroimage VBG cord-006870-f5w6fw6q 5101 48 time time NN cord-006870-f5w6fw6q 5101 49 ( ( -LRB- cord-006870-f5w6fw6q 5101 50 p<0.01 p<0.01 NNP cord-006870-f5w6fw6q 5101 51 ) ) -RRB- cord-006870-f5w6fw6q 5101 52 . . . cord-006870-f5w6fw6q 5102 1 In in IN cord-006870-f5w6fw6q 5102 2 patients patient NNS cord-006870-f5w6fw6q 5102 3 with with IN cord-006870-f5w6fw6q 5102 4 SAH SAH NNP cord-006870-f5w6fw6q 5102 5 and and CC cord-006870-f5w6fw6q 5102 6 mild mild JJ cord-006870-f5w6fw6q 5102 7 symptoms symptom NNS cord-006870-f5w6fw6q 5102 8 , , , cord-006870-f5w6fw6q 5102 9 LAPSS LAPSS NNP cord-006870-f5w6fw6q 5102 10 was be VBD cord-006870-f5w6fw6q 5102 11 not not RB cord-006870-f5w6fw6q 5102 12 a a DT cord-006870-f5w6fw6q 5102 13 sensitive sensitive JJ cord-006870-f5w6fw6q 5102 14 screening screening NN cord-006870-f5w6fw6q 5102 15 tool tool NN cord-006870-f5w6fw6q 5102 16 in in IN cord-006870-f5w6fw6q 5102 17 our -PRON- PRP$ cord-006870-f5w6fw6q 5102 18 series series NN cord-006870-f5w6fw6q 5102 19 . . . cord-006870-f5w6fw6q 5103 1 Hospital hospital NN cord-006870-f5w6fw6q 5103 2 and and CC cord-006870-f5w6fw6q 5103 3 pre pre JJ cord-006870-f5w6fw6q 5103 4 hospital hospital NN cord-006870-f5w6fw6q 5103 5 services service NNS cord-006870-f5w6fw6q 5103 6 using use VBG cord-006870-f5w6fw6q 5103 7 LAPSS LAPSS NNP cord-006870-f5w6fw6q 5103 8 for for IN cord-006870-f5w6fw6q 5103 9 triage triage NN cord-006870-f5w6fw6q 5103 10 of of IN cord-006870-f5w6fw6q 5103 11 patients patient NNS cord-006870-f5w6fw6q 5103 12 with with IN cord-006870-f5w6fw6q 5103 13 stroke stroke NN cord-006870-f5w6fw6q 5103 14 should should MD cord-006870-f5w6fw6q 5103 15 be be VB cord-006870-f5w6fw6q 5103 16 aware aware JJ cord-006870-f5w6fw6q 5103 17 of of IN cord-006870-f5w6fw6q 5103 18 this this DT cord-006870-f5w6fw6q 5103 19 limitation limitation NN cord-006870-f5w6fw6q 5103 20 and and CC cord-006870-f5w6fw6q 5103 21 include include VBP cord-006870-f5w6fw6q 5103 22 in in IN cord-006870-f5w6fw6q 5103 23 triage triage NN cord-006870-f5w6fw6q 5103 24 flowcharts flowchart NNS cord-006870-f5w6fw6q 5103 25 specific specific JJ cord-006870-f5w6fw6q 5103 26 questions question NNS cord-006870-f5w6fw6q 5103 27 evaluating evaluate VBG cord-006870-f5w6fw6q 5103 28 SAH SAH NNP cord-006870-f5w6fw6q 5103 29 specific specific JJ cord-006870-f5w6fw6q 5103 30 symptoms symptom NNS cord-006870-f5w6fw6q 5103 31 . . . cord-006870-f5w6fw6q 5104 1 Spontaneous spontaneous JJ cord-006870-f5w6fw6q 5104 2 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5104 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5104 4 ( ( -LRB- cord-006870-f5w6fw6q 5104 5 SAH SAH NNP cord-006870-f5w6fw6q 5104 6 ) ) -RRB- cord-006870-f5w6fw6q 5104 7 is be VBZ cord-006870-f5w6fw6q 5104 8 a a DT cord-006870-f5w6fw6q 5104 9 neurological neurological JJ cord-006870-f5w6fw6q 5104 10 emergency emergency NN cord-006870-f5w6fw6q 5104 11 , , , cord-006870-f5w6fw6q 5104 12 which which WDT cord-006870-f5w6fw6q 5104 13 despite despite IN cord-006870-f5w6fw6q 5104 14 current current JJ cord-006870-f5w6fw6q 5104 15 advances advance NNS cord-006870-f5w6fw6q 5104 16 in in IN cord-006870-f5w6fw6q 5104 17 management management NN cord-006870-f5w6fw6q 5104 18 strategies strategy NNS cord-006870-f5w6fw6q 5104 19 and and CC cord-006870-f5w6fw6q 5104 20 advent advent NN cord-006870-f5w6fw6q 5104 21 of of IN cord-006870-f5w6fw6q 5104 22 institutional institutional JJ cord-006870-f5w6fw6q 5104 23 protocols protocol NNS cord-006870-f5w6fw6q 5104 24 , , , cord-006870-f5w6fw6q 5104 25 remains remain VBZ cord-006870-f5w6fw6q 5104 26 with with IN cord-006870-f5w6fw6q 5104 27 significant significant JJ cord-006870-f5w6fw6q 5104 28 rates rate NNS cord-006870-f5w6fw6q 5104 29 of of IN cord-006870-f5w6fw6q 5104 30 mortality mortality NN cord-006870-f5w6fw6q 5104 31 due due IN cord-006870-f5w6fw6q 5104 32 to to IN cord-006870-f5w6fw6q 5104 33 poorly poorly RB cord-006870-f5w6fw6q 5104 34 understood understand VBN cord-006870-f5w6fw6q 5104 35 causes cause NNS cord-006870-f5w6fw6q 5104 36 . . . cord-006870-f5w6fw6q 5105 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5105 2 objectives objective NNS cord-006870-f5w6fw6q 5105 3 were be VBD cord-006870-f5w6fw6q 5105 4 to to TO cord-006870-f5w6fw6q 5105 5 characterize characterize VB cord-006870-f5w6fw6q 5105 6 in in IN cord-006870-f5w6fw6q 5105 7 - - HYPH cord-006870-f5w6fw6q 5105 8 hospital hospital NN cord-006870-f5w6fw6q 5105 9 mortality mortality NN cord-006870-f5w6fw6q 5105 10 by by IN cord-006870-f5w6fw6q 5105 11 evaluating evaluate VBG cord-006870-f5w6fw6q 5105 12 the the DT cord-006870-f5w6fw6q 5105 13 primary primary JJ cord-006870-f5w6fw6q 5105 14 cause cause NN cord-006870-f5w6fw6q 5105 15 of of IN cord-006870-f5w6fw6q 5105 16 death death NN cord-006870-f5w6fw6q 5105 17 and and CC cord-006870-f5w6fw6q 5105 18 externally externally RB cord-006870-f5w6fw6q 5105 19 validate validate VBP cord-006870-f5w6fw6q 5105 20 the the DT cord-006870-f5w6fw6q 5105 21 HAIR hair NN cord-006870-f5w6fw6q 5105 22 score score NN cord-006870-f5w6fw6q 5105 23 , , , cord-006870-f5w6fw6q 5105 24 a a DT cord-006870-f5w6fw6q 5105 25 clinical clinical JJ cord-006870-f5w6fw6q 5105 26 score score NN cord-006870-f5w6fw6q 5105 27 that that WDT cord-006870-f5w6fw6q 5105 28 prognosticates prognosticate VBZ cord-006870-f5w6fw6q 5105 29 mortality mortality NN cord-006870-f5w6fw6q 5105 30 . . . cord-006870-f5w6fw6q 5106 1 In in IN cord-006870-f5w6fw6q 5106 2 this this DT cord-006870-f5w6fw6q 5106 3 retrospective retrospective JJ cord-006870-f5w6fw6q 5106 4 cohort cohort NN cord-006870-f5w6fw6q 5106 5 study study NN cord-006870-f5w6fw6q 5106 6 , , , cord-006870-f5w6fw6q 5106 7 we -PRON- PRP cord-006870-f5w6fw6q 5106 8 reviewed review VBD cord-006870-f5w6fw6q 5106 9 all all DT cord-006870-f5w6fw6q 5106 10 SAH SAH NNP cord-006870-f5w6fw6q 5106 11 patients patient NNS cord-006870-f5w6fw6q 5106 12 admitted admit VBD cord-006870-f5w6fw6q 5106 13 to to IN cord-006870-f5w6fw6q 5106 14 our -PRON- PRP$ cord-006870-f5w6fw6q 5106 15 Neuro Neuro NNP cord-006870-f5w6fw6q 5106 16 - - HYPH cord-006870-f5w6fw6q 5106 17 ICU ICU NNP cord-006870-f5w6fw6q 5106 18 between between IN cord-006870-f5w6fw6q 5106 19 April April NNP cord-006870-f5w6fw6q 5106 20 1 1 CD cord-006870-f5w6fw6q 5106 21 , , , cord-006870-f5w6fw6q 5106 22 2010 2010 CD cord-006870-f5w6fw6q 5106 23 and and CC cord-006870-f5w6fw6q 5106 24 March March NNP cord-006870-f5w6fw6q 5106 25 31 31 CD cord-006870-f5w6fw6q 5106 26 , , , cord-006870-f5w6fw6q 5106 27 2016 2016 CD cord-006870-f5w6fw6q 5106 28 . . . cord-006870-f5w6fw6q 5107 1 Univariate univariate JJ cord-006870-f5w6fw6q 5107 2 and and CC cord-006870-f5w6fw6q 5107 3 multivariate multivariate JJ cord-006870-f5w6fw6q 5107 4 logistic logistic JJ cord-006870-f5w6fw6q 5107 5 regressions regression NNS cord-006870-f5w6fw6q 5107 6 were be VBD cord-006870-f5w6fw6q 5107 7 performed perform VBN cord-006870-f5w6fw6q 5107 8 to to TO cord-006870-f5w6fw6q 5107 9 identify identify VB cord-006870-f5w6fw6q 5107 10 predictors predictor NNS cord-006870-f5w6fw6q 5107 11 of of IN cord-006870-f5w6fw6q 5107 12 in in IN cord-006870-f5w6fw6q 5107 13 - - HYPH cord-006870-f5w6fw6q 5107 14 hospital hospital NN cord-006870-f5w6fw6q 5107 15 mortality mortality NN cord-006870-f5w6fw6q 5107 16 , , , cord-006870-f5w6fw6q 5107 17 our -PRON- PRP$ cord-006870-f5w6fw6q 5107 18 primary primary JJ cord-006870-f5w6fw6q 5107 19 outcome outcome NN cord-006870-f5w6fw6q 5107 20 . . . cord-006870-f5w6fw6q 5108 1 To to TO cord-006870-f5w6fw6q 5108 2 validate validate VB cord-006870-f5w6fw6q 5108 3 the the DT cord-006870-f5w6fw6q 5108 4 HAIR hair NN cord-006870-f5w6fw6q 5108 5 score score NN cord-006870-f5w6fw6q 5108 6 , , , cord-006870-f5w6fw6q 5108 7 the the DT cord-006870-f5w6fw6q 5108 8 model model NN cord-006870-f5w6fw6q 5108 9 's 's POS cord-006870-f5w6fw6q 5108 10 predictors predictor NNS cord-006870-f5w6fw6q 5108 11 were be VBD cord-006870-f5w6fw6q 5108 12 Hunt Hunt NNP cord-006870-f5w6fw6q 5108 13 and and CC cord-006870-f5w6fw6q 5108 14 Hess Hess NNP cord-006870-f5w6fw6q 5108 15 score score NN cord-006870-f5w6fw6q 5108 16 at at IN cord-006870-f5w6fw6q 5108 17 treatment treatment NN cord-006870-f5w6fw6q 5108 18 decision decision NN cord-006870-f5w6fw6q 5108 19 , , , cord-006870-f5w6fw6q 5108 20 age age NN cord-006870-f5w6fw6q 5108 21 , , , cord-006870-f5w6fw6q 5108 22 intraventricular intraventricular JJ cord-006870-f5w6fw6q 5108 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5108 24 , , , cord-006870-f5w6fw6q 5108 25 and and CC cord-006870-f5w6fw6q 5108 26 re re NN cord-006870-f5w6fw6q 5108 27 - - NN cord-006870-f5w6fw6q 5108 28 bleeding bleed VBG cord-006870-f5w6fw6q 5108 29 within within IN cord-006870-f5w6fw6q 5108 30 24 24 CD cord-006870-f5w6fw6q 5108 31 hours hour NNS cord-006870-f5w6fw6q 5108 32 . . . cord-006870-f5w6fw6q 5109 1 Discrimination discrimination NN cord-006870-f5w6fw6q 5109 2 was be VBD cord-006870-f5w6fw6q 5109 3 assessed assess VBN cord-006870-f5w6fw6q 5109 4 by by IN cord-006870-f5w6fw6q 5109 5 visualizing visualize VBG cord-006870-f5w6fw6q 5109 6 the the DT cord-006870-f5w6fw6q 5109 7 receiver receiver NN cord-006870-f5w6fw6q 5109 8 - - HYPH cord-006870-f5w6fw6q 5109 9 operating operate VBG cord-006870-f5w6fw6q 5109 10 curve curve NN cord-006870-f5w6fw6q 5109 11 and and CC cord-006870-f5w6fw6q 5109 12 calculating calculate VBG cord-006870-f5w6fw6q 5109 13 the the DT cord-006870-f5w6fw6q 5109 14 area area NN cord-006870-f5w6fw6q 5109 15 under under IN cord-006870-f5w6fw6q 5109 16 the the DT cord-006870-f5w6fw6q 5109 17 curve curve NN cord-006870-f5w6fw6q 5109 18 ( ( -LRB- cord-006870-f5w6fw6q 5109 19 AUC AUC NNP cord-006870-f5w6fw6q 5109 20 ) ) -RRB- cord-006870-f5w6fw6q 5109 21 . . . cord-006870-f5w6fw6q 5110 1 Among among IN cord-006870-f5w6fw6q 5110 2 434 434 CD cord-006870-f5w6fw6q 5110 3 SAH SAH NNP cord-006870-f5w6fw6q 5110 4 patients patient NNS cord-006870-f5w6fw6q 5110 5 with with IN cord-006870-f5w6fw6q 5110 6 a a DT cord-006870-f5w6fw6q 5110 7 median median JJ cord-006870-f5w6fw6q 5110 8 age age NN cord-006870-f5w6fw6q 5110 9 of of IN cord-006870-f5w6fw6q 5110 10 56 56 CD cord-006870-f5w6fw6q 5110 11 years year NNS cord-006870-f5w6fw6q 5110 12 ( ( -LRB- cord-006870-f5w6fw6q 5110 13 interquartile interquartile JJ cord-006870-f5w6fw6q 5110 14 range range NN cord-006870-f5w6fw6q 5110 15 , , , cord-006870-f5w6fw6q 5110 16 48 48 CD cord-006870-f5w6fw6q 5110 17 -65 -65 CD cord-006870-f5w6fw6q 5110 18 ) ) -RRB- cord-006870-f5w6fw6q 5110 19 , , , cord-006870-f5w6fw6q 5110 20 63.6 63.6 CD cord-006870-f5w6fw6q 5110 21 % % NN cord-006870-f5w6fw6q 5110 22 females female NNS cord-006870-f5w6fw6q 5110 23 , , , cord-006870-f5w6fw6q 5110 24 inhospital inhospital JJ cord-006870-f5w6fw6q 5110 25 mortality mortality NN cord-006870-f5w6fw6q 5110 26 was be VBD cord-006870-f5w6fw6q 5110 27 14.1 14.1 CD cord-006870-f5w6fw6q 5110 28 % % NN cord-006870-f5w6fw6q 5110 29 ( ( -LRB- cord-006870-f5w6fw6q 5110 30 n=61 n=61 NNP cord-006870-f5w6fw6q 5110 31 ) ) -RRB- cord-006870-f5w6fw6q 5110 32 . . . cord-006870-f5w6fw6q 5111 1 Of of IN cord-006870-f5w6fw6q 5111 2 those those DT cord-006870-f5w6fw6q 5111 3 , , , cord-006870-f5w6fw6q 5111 4 54 54 CD cord-006870-f5w6fw6q 5111 5 ( ( -LRB- cord-006870-f5w6fw6q 5111 6 88.5 88.5 CD cord-006870-f5w6fw6q 5111 7 % % NN cord-006870-f5w6fw6q 5111 8 ) ) -RRB- cord-006870-f5w6fw6q 5111 9 had have VBD cord-006870-f5w6fw6q 5111 10 a a DT cord-006870-f5w6fw6q 5111 11 neurological neurological JJ cord-006870-f5w6fw6q 5111 12 cause cause NN cord-006870-f5w6fw6q 5111 13 for for IN cord-006870-f5w6fw6q 5111 14 death death NN cord-006870-f5w6fw6q 5111 15 or or CC cord-006870-f5w6fw6q 5111 16 withdrawal withdrawal NN cord-006870-f5w6fw6q 5111 17 of of IN cord-006870-f5w6fw6q 5111 18 care care NN cord-006870-f5w6fw6q 5111 19 and and CC cord-006870-f5w6fw6q 5111 20 7 7 CD cord-006870-f5w6fw6q 5111 21 ( ( -LRB- cord-006870-f5w6fw6q 5111 22 11.5 11.5 CD cord-006870-f5w6fw6q 5111 23 % % NN cord-006870-f5w6fw6q 5111 24 ) ) -RRB- cord-006870-f5w6fw6q 5111 25 had have VBD cord-006870-f5w6fw6q 5111 26 a a DT cord-006870-f5w6fw6q 5111 27 cardiac cardiac JJ cord-006870-f5w6fw6q 5111 28 death death NN cord-006870-f5w6fw6q 5111 29 . . . cord-006870-f5w6fw6q 5112 1 Median median JJ cord-006870-f5w6fw6q 5112 2 time time NN cord-006870-f5w6fw6q 5112 3 from from IN cord-006870-f5w6fw6q 5112 4 SAH SAH NNP cord-006870-f5w6fw6q 5112 5 to to IN cord-006870-f5w6fw6q 5112 6 death death NN cord-006870-f5w6fw6q 5112 7 was be VBD cord-006870-f5w6fw6q 5112 8 6 6 CD cord-006870-f5w6fw6q 5112 9 days day NNS cord-006870-f5w6fw6q 5112 10 . . . cord-006870-f5w6fw6q 5113 1 The the DT cord-006870-f5w6fw6q 5113 2 main main JJ cord-006870-f5w6fw6q 5113 3 causes cause NNS cord-006870-f5w6fw6q 5113 4 of of IN cord-006870-f5w6fw6q 5113 5 death death NN cord-006870-f5w6fw6q 5113 6 were be VBD cord-006870-f5w6fw6q 5113 7 the the DT cord-006870-f5w6fw6q 5113 8 primary primary JJ cord-006870-f5w6fw6q 5113 9 effects effect NNS cord-006870-f5w6fw6q 5113 10 of of IN cord-006870-f5w6fw6q 5113 11 the the DT cord-006870-f5w6fw6q 5113 12 initial initial JJ cord-006870-f5w6fw6q 5113 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5113 14 , , , cord-006870-f5w6fw6q 5113 15 re re NN cord-006870-f5w6fw6q 5113 16 - - JJ cord-006870-f5w6fw6q 5113 17 bleeding bleeding JJ cord-006870-f5w6fw6q 5113 18 and and CC cord-006870-f5w6fw6q 5113 19 refractory refractory JJ cord-006870-f5w6fw6q 5113 20 edema edema NN cord-006870-f5w6fw6q 5113 21 . . . cord-006870-f5w6fw6q 5114 1 Factors factor NNS cord-006870-f5w6fw6q 5114 2 significantly significantly RB cord-006870-f5w6fw6q 5114 3 associated associate VBD cord-006870-f5w6fw6q 5114 4 with with IN cord-006870-f5w6fw6q 5114 5 in in IN cord-006870-f5w6fw6q 5114 6 - - HYPH cord-006870-f5w6fw6q 5114 7 hospital hospital NN cord-006870-f5w6fw6q 5114 8 mortality mortality NN cord-006870-f5w6fw6q 5114 9 in in IN cord-006870-f5w6fw6q 5114 10 the the DT cord-006870-f5w6fw6q 5114 11 multivariate multivariate JJ cord-006870-f5w6fw6q 5114 12 analysis analysis NN cord-006870-f5w6fw6q 5114 13 were be VBD cord-006870-f5w6fw6q 5114 14 age age NN cord-006870-f5w6fw6q 5114 15 , , , cord-006870-f5w6fw6q 5114 16 Hunt Hunt NNP cord-006870-f5w6fw6q 5114 17 and and CC cord-006870-f5w6fw6q 5114 18 Hess Hess NNP cord-006870-f5w6fw6q 5114 19 score score NN cord-006870-f5w6fw6q 5114 20 , , , cord-006870-f5w6fw6q 5114 21 and and CC cord-006870-f5w6fw6q 5114 22 intra intra JJ cord-006870-f5w6fw6q 5114 23 - - JJ cord-006870-f5w6fw6q 5114 24 cerebral cerebral JJ cord-006870-f5w6fw6q 5114 25 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5114 26 . . . cord-006870-f5w6fw6q 5115 1 Maximum maximum JJ cord-006870-f5w6fw6q 5115 2 lumen lumen JJ cord-006870-f5w6fw6q 5115 3 size size NN cord-006870-f5w6fw6q 5115 4 was be VBD cord-006870-f5w6fw6q 5115 5 also also RB cord-006870-f5w6fw6q 5115 6 a a DT cord-006870-f5w6fw6q 5115 7 significant significant JJ cord-006870-f5w6fw6q 5115 8 risk risk NN cord-006870-f5w6fw6q 5115 9 factor factor NN cord-006870-f5w6fw6q 5115 10 among among IN cord-006870-f5w6fw6q 5115 11 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5115 12 SAH SAH NNP cord-006870-f5w6fw6q 5115 13 patients patient NNS cord-006870-f5w6fw6q 5115 14 . . . cord-006870-f5w6fw6q 5116 1 The the DT cord-006870-f5w6fw6q 5116 2 HAIR hair NN cord-006870-f5w6fw6q 5116 3 score score NN cord-006870-f5w6fw6q 5116 4 had have VBD cord-006870-f5w6fw6q 5116 5 a a DT cord-006870-f5w6fw6q 5116 6 satisfactory satisfactory JJ cord-006870-f5w6fw6q 5116 7 discriminative discriminative JJ cord-006870-f5w6fw6q 5116 8 ability ability NN cord-006870-f5w6fw6q 5116 9 , , , cord-006870-f5w6fw6q 5116 10 with with IN cord-006870-f5w6fw6q 5116 11 an an DT cord-006870-f5w6fw6q 5116 12 AUC AUC NNP cord-006870-f5w6fw6q 5116 13 of of IN cord-006870-f5w6fw6q 5116 14 0.89 0.89 CD cord-006870-f5w6fw6q 5116 15 . . . cord-006870-f5w6fw6q 5117 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5117 2 in in IN cord-006870-f5w6fw6q 5117 3 - - HYPH cord-006870-f5w6fw6q 5117 4 hospital hospital NN cord-006870-f5w6fw6q 5117 5 mortality mortality NN cord-006870-f5w6fw6q 5117 6 is be VBZ cord-006870-f5w6fw6q 5117 7 lower low JJR cord-006870-f5w6fw6q 5117 8 than than IN cord-006870-f5w6fw6q 5117 9 previous previous JJ cord-006870-f5w6fw6q 5117 10 reports report NNS cord-006870-f5w6fw6q 5117 11 , , , cord-006870-f5w6fw6q 5117 12 attesting attest VBG cord-006870-f5w6fw6q 5117 13 to to IN cord-006870-f5w6fw6q 5117 14 the the DT cord-006870-f5w6fw6q 5117 15 continuing continue VBG cord-006870-f5w6fw6q 5117 16 improvement improvement NN cord-006870-f5w6fw6q 5117 17 of of IN cord-006870-f5w6fw6q 5117 18 our -PRON- PRP$ cord-006870-f5w6fw6q 5117 19 protocolized protocolized JJ cord-006870-f5w6fw6q 5117 20 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5117 21 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5117 22 care care NN cord-006870-f5w6fw6q 5117 23 . . . cord-006870-f5w6fw6q 5118 1 The the DT cord-006870-f5w6fw6q 5118 2 major major JJ cord-006870-f5w6fw6q 5118 3 causes cause NNS cord-006870-f5w6fw6q 5118 4 are be VBP cord-006870-f5w6fw6q 5118 5 the the DT cord-006870-f5w6fw6q 5118 6 same same JJ cord-006870-f5w6fw6q 5118 7 as as IN cord-006870-f5w6fw6q 5118 8 previous previous JJ cord-006870-f5w6fw6q 5118 9 reports report NNS cord-006870-f5w6fw6q 5118 10 . . . cord-006870-f5w6fw6q 5119 1 The the DT cord-006870-f5w6fw6q 5119 2 HAIR hair NN cord-006870-f5w6fw6q 5119 3 score score NN cord-006870-f5w6fw6q 5119 4 showed show VBD cord-006870-f5w6fw6q 5119 5 good good JJ cord-006870-f5w6fw6q 5119 6 discrimination discrimination NN cord-006870-f5w6fw6q 5119 7 and and CC cord-006870-f5w6fw6q 5119 8 could could MD cord-006870-f5w6fw6q 5119 9 be be VB cord-006870-f5w6fw6q 5119 10 a a DT cord-006870-f5w6fw6q 5119 11 useful useful JJ cord-006870-f5w6fw6q 5119 12 tool tool NN cord-006870-f5w6fw6q 5119 13 for for IN cord-006870-f5w6fw6q 5119 14 predicting predict VBG cord-006870-f5w6fw6q 5119 15 mortality mortality NN cord-006870-f5w6fw6q 5119 16 . . . cord-006870-f5w6fw6q 5120 1 So so RB cord-006870-f5w6fw6q 5120 2 far far RB cord-006870-f5w6fw6q 5120 3 , , , cord-006870-f5w6fw6q 5120 4 scientific scientific JJ cord-006870-f5w6fw6q 5120 5 and and CC cord-006870-f5w6fw6q 5120 6 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5120 7 efforts effort NNS cord-006870-f5w6fw6q 5120 8 mainly mainly RB cord-006870-f5w6fw6q 5120 9 focused focus VBD cord-006870-f5w6fw6q 5120 10 on on IN cord-006870-f5w6fw6q 5120 11 the the DT cord-006870-f5w6fw6q 5120 12 prevention prevention NN cord-006870-f5w6fw6q 5120 13 of of IN cord-006870-f5w6fw6q 5120 14 rebleeding rebleeding NN cord-006870-f5w6fw6q 5120 15 and and CC cord-006870-f5w6fw6q 5120 16 ischemic ischemic JJ cord-006870-f5w6fw6q 5120 17 complications(DCI complications(dci $ cord-006870-f5w6fw6q 5120 18 ) ) -RRB- cord-006870-f5w6fw6q 5120 19 in in IN cord-006870-f5w6fw6q 5120 20 patients patient NNS cord-006870-f5w6fw6q 5120 21 with with IN cord-006870-f5w6fw6q 5120 22 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5120 23 hemorrhage(SAH hemorrhage(sah JJ cord-006870-f5w6fw6q 5120 24 ) ) -RRB- cord-006870-f5w6fw6q 5120 25 . . . cord-006870-f5w6fw6q 5121 1 However however RB cord-006870-f5w6fw6q 5121 2 , , , cord-006870-f5w6fw6q 5121 3 data datum NNS cord-006870-f5w6fw6q 5121 4 regarding regard VBG cord-006870-f5w6fw6q 5121 5 the the DT cord-006870-f5w6fw6q 5121 6 impact impact NN cord-006870-f5w6fw6q 5121 7 of of IN cord-006870-f5w6fw6q 5121 8 parenchymatous parenchymatous JJ cord-006870-f5w6fw6q 5121 9 hemorrhage(PH hemorrhage(ph ADD cord-006870-f5w6fw6q 5121 10 ) ) -RRB- cord-006870-f5w6fw6q 5121 11 on on IN cord-006870-f5w6fw6q 5121 12 longterm longterm JJ cord-006870-f5w6fw6q 5121 13 outcome outcome NN cord-006870-f5w6fw6q 5121 14 in in IN cord-006870-f5w6fw6q 5121 15 these these DT cord-006870-f5w6fw6q 5121 16 patients patient NNS cord-006870-f5w6fw6q 5121 17 is be VBZ cord-006870-f5w6fw6q 5121 18 limited limited JJ cord-006870-f5w6fw6q 5121 19 . . . cord-006870-f5w6fw6q 5122 1 All all DT cord-006870-f5w6fw6q 5122 2 consecutive consecutive JJ cord-006870-f5w6fw6q 5122 3 patients patient NNS cord-006870-f5w6fw6q 5122 4 with with IN cord-006870-f5w6fw6q 5122 5 atraumatic atraumatic JJ cord-006870-f5w6fw6q 5122 6 SAH SAH NNP cord-006870-f5w6fw6q 5122 7 admitted admit VBD cord-006870-f5w6fw6q 5122 8 to to IN cord-006870-f5w6fw6q 5122 9 our -PRON- PRP$ cord-006870-f5w6fw6q 5122 10 hospital hospital NN cord-006870-f5w6fw6q 5122 11 over over IN cord-006870-f5w6fw6q 5122 12 a a DT cord-006870-f5w6fw6q 5122 13 5-year 5-year CD cord-006870-f5w6fw6q 5122 14 - - HYPH cord-006870-f5w6fw6q 5122 15 period(2008 period(2008 NN cord-006870-f5w6fw6q 5122 16 - - HYPH cord-006870-f5w6fw6q 5122 17 2012 2012 CD cord-006870-f5w6fw6q 5122 18 ) ) -RRB- cord-006870-f5w6fw6q 5122 19 were be VBD cord-006870-f5w6fw6q 5122 20 retrospectively retrospectively RB cord-006870-f5w6fw6q 5122 21 analyzed analyze VBN cord-006870-f5w6fw6q 5122 22 . . . cord-006870-f5w6fw6q 5123 1 Extent extent NN cord-006870-f5w6fw6q 5123 2 of of IN cord-006870-f5w6fw6q 5123 3 SAH SAH NNP cord-006870-f5w6fw6q 5123 4 as as RB cord-006870-f5w6fw6q 5123 5 well well RB cord-006870-f5w6fw6q 5123 6 as as IN cord-006870-f5w6fw6q 5123 7 presence presence NN cord-006870-f5w6fw6q 5123 8 , , , cord-006870-f5w6fw6q 5123 9 localization localization NN cord-006870-f5w6fw6q 5123 10 and and CC cord-006870-f5w6fw6q 5123 11 volume volume NN cord-006870-f5w6fw6q 5123 12 of of IN cord-006870-f5w6fw6q 5123 13 PH PH NNP cord-006870-f5w6fw6q 5123 14 were be VBD cord-006870-f5w6fw6q 5123 15 evaluated evaluate VBN cord-006870-f5w6fw6q 5123 16 . . . cord-006870-f5w6fw6q 5124 1 Functional functional JJ cord-006870-f5w6fw6q 5124 2 and and CC cord-006870-f5w6fw6q 5124 3 health health NN cord-006870-f5w6fw6q 5124 4 outcome outcome NN cord-006870-f5w6fw6q 5124 5 were be VBD cord-006870-f5w6fw6q 5124 6 assessed assess VBN cord-006870-f5w6fw6q 5124 7 after after IN cord-006870-f5w6fw6q 5124 8 12 12 CD cord-006870-f5w6fw6q 5124 9 months month NNS cord-006870-f5w6fw6q 5124 10 using use VBG cord-006870-f5w6fw6q 5124 11 the the DT cord-006870-f5w6fw6q 5124 12 modified modify VBN cord-006870-f5w6fw6q 5124 13 Rankin Rankin NNP cord-006870-f5w6fw6q 5124 14 scale scale NN cord-006870-f5w6fw6q 5124 15 ( ( -LRB- cord-006870-f5w6fw6q 5124 16 unfavorable:3 unfavorable:3 NNP cord-006870-f5w6fw6q 5124 17 - - HYPH cord-006870-f5w6fw6q 5124 18 6 6 CD cord-006870-f5w6fw6q 5124 19 ) ) -RRB- cord-006870-f5w6fw6q 5124 20 and and CC cord-006870-f5w6fw6q 5124 21 the the DT cord-006870-f5w6fw6q 5124 22 EQ-5D. EQ-5D. NNP cord-006870-f5w6fw6q 5124 23 Propensity Propensity NNP cord-006870-f5w6fw6q 5124 24 - - HYPH cord-006870-f5w6fw6q 5124 25 score(PS)-matching score(ps)-matching NN cord-006870-f5w6fw6q 5124 26 was be VBD cord-006870-f5w6fw6q 5124 27 performed perform VBN cord-006870-f5w6fw6q 5124 28 to to TO cord-006870-f5w6fw6q 5124 29 minimize minimize VB cord-006870-f5w6fw6q 5124 30 potential potential JJ cord-006870-f5w6fw6q 5124 31 bias bias NN cord-006870-f5w6fw6q 5124 32 due due IN cord-006870-f5w6fw6q 5124 33 to to IN cord-006870-f5w6fw6q 5124 34 confounding confounding JJ cord-006870-f5w6fw6q 5124 35 variables variable NNS cord-006870-f5w6fw6q 5124 36 between between IN cord-006870-f5w6fw6q 5124 37 SAH SAH NNP cord-006870-f5w6fw6q 5124 38 - - HYPH cord-006870-f5w6fw6q 5124 39 patients patient NNS cord-006870-f5w6fw6q 5124 40 with with IN cord-006870-f5w6fw6q 5124 41 and and CC cord-006870-f5w6fw6q 5124 42 without without IN cord-006870-f5w6fw6q 5124 43 PH PH NNP cord-006870-f5w6fw6q 5124 44 . . . cord-006870-f5w6fw6q 5125 1 Of of IN cord-006870-f5w6fw6q 5125 2 overall overall RB cord-006870-f5w6fw6q 5125 3 494 494 CD cord-006870-f5w6fw6q 5125 4 patients patient NNS cord-006870-f5w6fw6q 5125 5 with with IN cord-006870-f5w6fw6q 5125 6 atraumatic atraumatic JJ cord-006870-f5w6fw6q 5125 7 SAH SAH NNP cord-006870-f5w6fw6q 5125 8 , , , cord-006870-f5w6fw6q 5125 9 85(17.2 85(17.2 CD cord-006870-f5w6fw6q 5125 10 % % NN cord-006870-f5w6fw6q 5125 11 ) ) -RRB- cord-006870-f5w6fw6q 5125 12 patients patient NNS cord-006870-f5w6fw6q 5125 13 had have VBD cord-006870-f5w6fw6q 5125 14 PH PH NNP cord-006870-f5w6fw6q 5125 15 on on IN cord-006870-f5w6fw6q 5125 16 initial initial JJ cord-006870-f5w6fw6q 5125 17 imaging imaging NN cord-006870-f5w6fw6q 5125 18 . . . cord-006870-f5w6fw6q 5126 1 PH ph NN cord-006870-f5w6fw6q 5126 2 - - HYPH cord-006870-f5w6fw6q 5126 3 patients patient NNS cord-006870-f5w6fw6q 5126 4 had have VBD cord-006870-f5w6fw6q 5126 5 a a DT cord-006870-f5w6fw6q 5126 6 worse bad JJR cord-006870-f5w6fw6q 5126 7 clinical clinical JJ cord-006870-f5w6fw6q 5126 8 condition condition NN cord-006870-f5w6fw6q 5126 9 on on IN cord-006870-f5w6fw6q 5126 10 admission admission NN cord-006870-f5w6fw6q 5127 1 ( ( -LRB- cord-006870-f5w6fw6q 5127 2 WFNS WFNS NNP cord-006870-f5w6fw6q 5127 3 : : : cord-006870-f5w6fw6q 5128 1 PH PH NNP cord-006870-f5w6fw6q 5128 2 4(3 4(3 NNP cord-006870-f5w6fw6q 5128 3 - - HYPH cord-006870-f5w6fw6q 5128 4 5 5 CD cord-006870-f5w6fw6q 5128 5 ) ) -RRB- cord-006870-f5w6fw6q 5129 1 vs. vs. CC cord-006870-f5w6fw6q 5129 2 ØPH ØPH NNP cord-006870-f5w6fw6q 5129 3 2(1 2(1 NNP cord-006870-f5w6fw6q 5129 4 - - HYPH cord-006870-f5w6fw6q 5129 5 4);p<0.001 4);p<0.001 CD cord-006870-f5w6fw6q 5129 6 ) ) -RRB- cord-006870-f5w6fw6q 5129 7 and and CC cord-006870-f5w6fw6q 5129 8 a a DT cord-006870-f5w6fw6q 5129 9 greater great JJR cord-006870-f5w6fw6q 5129 10 extent extent NN cord-006870-f5w6fw6q 5129 11 of of IN cord-006870-f5w6fw6q 5129 12 SAH SAH NNP cord-006870-f5w6fw6q 5129 13 ( ( -LRB- cord-006870-f5w6fw6q 5129 14 modified modify VBN cord-006870-f5w6fw6q 5129 15 Fisher Fisher NNP cord-006870-f5w6fw6q 5129 16 : : : cord-006870-f5w6fw6q 5129 17 PH PH NNP cord-006870-f5w6fw6q 5129 18 3(2 3(2 NNP cord-006870-f5w6fw6q 5129 19 - - HYPH cord-006870-f5w6fw6q 5129 20 4 4 CD cord-006870-f5w6fw6q 5129 21 ) ) -RRB- cord-006870-f5w6fw6q 5129 22 vs. vs. FW cord-006870-f5w6fw6q 5129 23 ØPH ØPH NNP cord-006870-f5w6fw6q 5129 24 2(1 2(1 NNP cord-006870-f5w6fw6q 5129 25 - - HYPH cord-006870-f5w6fw6q 5129 26 3);p=0.001 3);p=0.001 CD cord-006870-f5w6fw6q 5129 27 ) ) -RRB- cord-006870-f5w6fw6q 5129 28 . . . cord-006870-f5w6fw6q 5130 1 Median median JJ cord-006870-f5w6fw6q 5130 2 PH ph NN cord-006870-f5w6fw6q 5130 3 - - HYPH cord-006870-f5w6fw6q 5130 4 volume volume NN cord-006870-f5w6fw6q 5130 5 was be VBD cord-006870-f5w6fw6q 5130 6 11.0(5.4 11.0(5.4 CD cord-006870-f5w6fw6q 5130 7 - - HYPH cord-006870-f5w6fw6q 5130 8 31.8)ml 31.8)ml NNS cord-006870-f5w6fw6q 5130 9 with with IN cord-006870-f5w6fw6q 5130 10 largest large JJS cord-006870-f5w6fw6q 5130 11 volumes volume NNS cord-006870-f5w6fw6q 5130 12 in in IN cord-006870-f5w6fw6q 5130 13 patients patient NNS cord-006870-f5w6fw6q 5130 14 with with IN cord-006870-f5w6fw6q 5130 15 ruptured ruptured JJ cord-006870-f5w6fw6q 5130 16 ) ) -RRB- cord-006870-f5w6fw6q 5130 17 ml ml NN cord-006870-f5w6fw6q 5130 18 ) ) -RRB- cord-006870-f5w6fw6q 5130 19 . . . cord-006870-f5w6fw6q 5131 1 After after IN cord-006870-f5w6fw6q 5131 2 successful successful JJ cord-006870-f5w6fw6q 5131 3 PS ps NN cord-006870-f5w6fw6q 5131 4 - - HYPH cord-006870-f5w6fw6q 5131 5 matching matching NN cord-006870-f5w6fw6q 5131 6 ( ( -LRB- cord-006870-f5w6fw6q 5131 7 parameters parameter NNS cord-006870-f5w6fw6q 5131 8 : : : cord-006870-f5w6fw6q 5131 9 age age NN cord-006870-f5w6fw6q 5131 10 , , , cord-006870-f5w6fw6q 5131 11 WFNS WFNS NNP cord-006870-f5w6fw6q 5131 12 , , , cord-006870-f5w6fw6q 5131 13 modified modify VBN cord-006870-f5w6fw6q 5131 14 Fisher Fisher NNP cord-006870-f5w6fw6q 5131 15 and and CC cord-006870-f5w6fw6q 5131 16 Graeb Graeb NNP cord-006870-f5w6fw6q 5131 17 score score NN cord-006870-f5w6fw6q 5131 18 ) ) -RRB- cord-006870-f5w6fw6q 5132 1 patients patient NNS cord-006870-f5w6fw6q 5132 2 with with IN cord-006870-f5w6fw6q 5132 3 PH PH NNP cord-006870-f5w6fw6q 5132 4 had have VBD cord-006870-f5w6fw6q 5132 5 worse bad JJR cord-006870-f5w6fw6q 5132 6 functional functional JJ cord-006870-f5w6fw6q 5132 7 and and CC cord-006870-f5w6fw6q 5132 8 health health NN cord-006870-f5w6fw6q 5132 9 outcome outcome NN cord-006870-f5w6fw6q 5132 10 after after IN cord-006870-f5w6fw6q 5132 11 12 12 CD cord-006870-f5w6fw6q 5132 12 months month NNS cord-006870-f5w6fw6q 5132 13 compared compare VBN cord-006870-f5w6fw6q 5132 14 to to IN cord-006870-f5w6fw6q 5132 15 those those DT cord-006870-f5w6fw6q 5132 16 without without IN cord-006870-f5w6fw6q 5132 17 PH PH NNP cord-006870-f5w6fw6q 5132 18 ( ( -LRB- cord-006870-f5w6fw6q 5133 1 mRS mrs DT cord-006870-f5w6fw6q 5133 2 3 3 CD cord-006870-f5w6fw6q 5133 3 - - SYM cord-006870-f5w6fw6q 5133 4 6 6 CD cord-006870-f5w6fw6q 5133 5 : : : cord-006870-f5w6fw6q 5133 6 PH PH NNP cord-006870-f5w6fw6q 5133 7 56/82(68.3 56/82(68.3 CD cord-006870-f5w6fw6q 5133 8 % % NN cord-006870-f5w6fw6q 5133 9 ) ) -RRB- cord-006870-f5w6fw6q 5133 10 vs. vs. FW cord-006870-f5w6fw6q 5133 11 ØPH øph NN cord-006870-f5w6fw6q 5133 12 33/78(42.3%);p=0.001 33/78(42.3%);p=0.001 CD cord-006870-f5w6fw6q 5133 13 ; ; : cord-006870-f5w6fw6q 5133 14 EQ-5D eq-5d NN cord-006870-f5w6fw6q 5133 15 : : : cord-006870-f5w6fw6q 5134 1 PH PH NNP cord-006870-f5w6fw6q 5134 2 50(30 50(30 CD cord-006870-f5w6fw6q 5134 3 - - HYPH cord-006870-f5w6fw6q 5134 4 70 70 CD cord-006870-f5w6fw6q 5134 5 ) ) -RRB- cord-006870-f5w6fw6q 5134 6 vs. vs. FW cord-006870-f5w6fw6q 5134 7 ØPH ØPH NNP cord-006870-f5w6fw6q 5134 8 80(65 80(65 CD cord-006870-f5w6fw6q 5134 9 - - HYPH cord-006870-f5w6fw6q 5134 10 95 95 CD cord-006870-f5w6fw6q 5134 11 ) ) -RRB- cord-006870-f5w6fw6q 5134 12 ; ; : cord-006870-f5w6fw6q 5134 13 p<0.001 p<0.001 LS cord-006870-f5w6fw6q 5134 14 ) ) -RRB- cord-006870-f5w6fw6q 5134 15 . . . cord-006870-f5w6fw6q 5135 1 In in IN cord-006870-f5w6fw6q 5135 2 multivariate multivariate JJ cord-006870-f5w6fw6q 5135 3 analysis analysis NN cord-006870-f5w6fw6q 5135 4 presence presence NN cord-006870-f5w6fw6q 5135 5 of of IN cord-006870-f5w6fw6q 5135 6 PH PH NNP cord-006870-f5w6fw6q 5135 7 was be VBD cord-006870-f5w6fw6q 5135 8 the the DT cord-006870-f5w6fw6q 5135 9 strongest strong JJS cord-006870-f5w6fw6q 5135 10 independent independent JJ cord-006870-f5w6fw6q 5135 11 predictor predictor NN cord-006870-f5w6fw6q 5135 12 of of IN cord-006870-f5w6fw6q 5135 13 unfavorable unfavorable JJ cord-006870-f5w6fw6q 5135 14 outcome outcome NN cord-006870-f5w6fw6q 5135 15 after after IN cord-006870-f5w6fw6q 5135 16 12 12 CD cord-006870-f5w6fw6q 5135 17 months month NNS cord-006870-f5w6fw6q 5135 18 followed follow VBN cord-006870-f5w6fw6q 5135 19 by by IN cord-006870-f5w6fw6q 5135 20 the the DT cord-006870-f5w6fw6q 5135 21 occurrence occurrence NN cord-006870-f5w6fw6q 5135 22 of of IN cord-006870-f5w6fw6q 5135 23 DCI DCI NNP cord-006870-f5w6fw6q 5135 24 ( ( -LRB- cord-006870-f5w6fw6q 5135 25 risk risk NN cord-006870-f5w6fw6q 5135 26 - - HYPH cord-006870-f5w6fw6q 5135 27 ratio(95%CI ratio(95%ci NN cord-006870-f5w6fw6q 5135 28 ) ) -RRB- cord-006870-f5w6fw6q 5135 29 : : : cord-006870-f5w6fw6q 5136 1 PH PH NNP cord-006870-f5w6fw6q 5136 2 4.5(2.0 4.5(2.0 CD cord-006870-f5w6fw6q 5136 3 - - SYM cord-006870-f5w6fw6q 5136 4 10.0 10.0 CD cord-006870-f5w6fw6q 5136 5 ) ) -RRB- cord-006870-f5w6fw6q 5136 6 ; ; : cord-006870-f5w6fw6q 5136 7 p<0.001 p<0.001 LS cord-006870-f5w6fw6q 5136 8 ) ) -RRB- cord-006870-f5w6fw6q 5136 9 . . . cord-006870-f5w6fw6q 5137 1 Parenchymatous parenchymatous JJ cord-006870-f5w6fw6q 5137 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5137 3 is be VBZ cord-006870-f5w6fw6q 5137 4 frequent frequent JJ cord-006870-f5w6fw6q 5137 5 and and CC cord-006870-f5w6fw6q 5137 6 associated associate VBN cord-006870-f5w6fw6q 5137 7 with with IN cord-006870-f5w6fw6q 5137 8 functional functional JJ cord-006870-f5w6fw6q 5137 9 and and CC cord-006870-f5w6fw6q 5137 10 subjective subjective JJ cord-006870-f5w6fw6q 5137 11 impairments impairment NNS cord-006870-f5w6fw6q 5137 12 in in IN cord-006870-f5w6fw6q 5137 13 patients patient NNS cord-006870-f5w6fw6q 5137 14 with with IN cord-006870-f5w6fw6q 5137 15 atraumatic atraumatic JJ cord-006870-f5w6fw6q 5137 16 SAH SAH NNP cord-006870-f5w6fw6q 5137 17 . . . cord-006870-f5w6fw6q 5138 1 Aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 5138 2 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5138 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5138 4 ( ( -LRB- cord-006870-f5w6fw6q 5138 5 aSAH aSAH NNP cord-006870-f5w6fw6q 5138 6 ) ) -RRB- cord-006870-f5w6fw6q 5138 7 is be VBZ cord-006870-f5w6fw6q 5138 8 associated associate VBN cord-006870-f5w6fw6q 5138 9 with with IN cord-006870-f5w6fw6q 5138 10 early early JJ cord-006870-f5w6fw6q 5138 11 and and CC cord-006870-f5w6fw6q 5138 12 delayed delayed JJ cord-006870-f5w6fw6q 5138 13 brain brain NN cord-006870-f5w6fw6q 5138 14 injury injury NN cord-006870-f5w6fw6q 5138 15 . . . cord-006870-f5w6fw6q 5139 1 Insulin insulin NN cord-006870-f5w6fw6q 5139 2 growth growth NN cord-006870-f5w6fw6q 5139 3 factor factor NN cord-006870-f5w6fw6q 5139 4 ( ( -LRB- cord-006870-f5w6fw6q 5139 5 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5139 6 ) ) -RRB- cord-006870-f5w6fw6q 5139 7 is be VBZ cord-006870-f5w6fw6q 5139 8 a a DT cord-006870-f5w6fw6q 5139 9 potent potent JJ cord-006870-f5w6fw6q 5139 10 cellular cellular JJ cord-006870-f5w6fw6q 5139 11 growth growth NN cord-006870-f5w6fw6q 5139 12 - - HYPH cord-006870-f5w6fw6q 5139 13 promoting promote VBG cord-006870-f5w6fw6q 5139 14 factor factor NN cord-006870-f5w6fw6q 5139 15 with with IN cord-006870-f5w6fw6q 5139 16 demonstrated demonstrate VBN cord-006870-f5w6fw6q 5139 17 independent independent JJ cord-006870-f5w6fw6q 5139 18 neuroprotective neuroprotective JJ cord-006870-f5w6fw6q 5139 19 actions action NNS cord-006870-f5w6fw6q 5139 20 in in IN cord-006870-f5w6fw6q 5139 21 stroke stroke NN cord-006870-f5w6fw6q 5139 22 and and CC cord-006870-f5w6fw6q 5139 23 neurologic neurologic JJ cord-006870-f5w6fw6q 5139 24 disease disease NN cord-006870-f5w6fw6q 5139 25 but but CC cord-006870-f5w6fw6q 5139 26 has have VBZ cord-006870-f5w6fw6q 5139 27 not not RB cord-006870-f5w6fw6q 5139 28 been be VBN cord-006870-f5w6fw6q 5139 29 well well RB cord-006870-f5w6fw6q 5139 30 characterized characterize VBN cord-006870-f5w6fw6q 5139 31 after after IN cord-006870-f5w6fw6q 5139 32 aSAH asah JJ cord-006870-f5w6fw6q 5139 33 . . . cord-006870-f5w6fw6q 5140 1 This this DT cord-006870-f5w6fw6q 5140 2 study study NN cord-006870-f5w6fw6q 5140 3 sought seek VBD cord-006870-f5w6fw6q 5140 4 to to TO cord-006870-f5w6fw6q 5140 5 examine examine VB cord-006870-f5w6fw6q 5140 6 the the DT cord-006870-f5w6fw6q 5140 7 relationship relationship NN cord-006870-f5w6fw6q 5140 8 between between IN cord-006870-f5w6fw6q 5140 9 plasma plasma NN cord-006870-f5w6fw6q 5140 10 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5140 11 levels level NNS cord-006870-f5w6fw6q 5140 12 and and CC cord-006870-f5w6fw6q 5140 13 outcomes outcome NNS cord-006870-f5w6fw6q 5140 14 after after IN cord-006870-f5w6fw6q 5140 15 aSAH asah JJ cord-006870-f5w6fw6q 5140 16 . . . cord-006870-f5w6fw6q 5141 1 This this DT cord-006870-f5w6fw6q 5141 2 cohort cohort NN cord-006870-f5w6fw6q 5141 3 of of IN cord-006870-f5w6fw6q 5141 4 128 128 CD cord-006870-f5w6fw6q 5141 5 aSAH asah JJ cord-006870-f5w6fw6q 5141 6 patients patient NNS cord-006870-f5w6fw6q 5141 7 was be VBD cord-006870-f5w6fw6q 5141 8 50.6 50.6 CD cord-006870-f5w6fw6q 5141 9 years year NNS cord-006870-f5w6fw6q 5141 10 ( ( -LRB- cord-006870-f5w6fw6q 5141 11 SD SD NNP cord-006870-f5w6fw6q 5141 12 10.03 10.03 CD cord-006870-f5w6fw6q 5141 13 ) ) -RRB- cord-006870-f5w6fw6q 5141 14 and and CC cord-006870-f5w6fw6q 5141 15 female female JJ cord-006870-f5w6fw6q 5141 16 ( ( -LRB- cord-006870-f5w6fw6q 5141 17 66 66 CD cord-006870-f5w6fw6q 5141 18 % % NN cord-006870-f5w6fw6q 5141 19 ) ) -RRB- cord-006870-f5w6fw6q 5141 20 with with IN cord-006870-f5w6fw6q 5141 21 a a DT cord-006870-f5w6fw6q 5141 22 mean mean JJ cord-006870-f5w6fw6q 5141 23 HH HH NNP cord-006870-f5w6fw6q 5141 24 3 3 CD cord-006870-f5w6fw6q 5141 25 ( ( -LRB- cord-006870-f5w6fw6q 5141 26 45 45 CD cord-006870-f5w6fw6q 5141 27 % % NN cord-006870-f5w6fw6q 5141 28 ) ) -RRB- cord-006870-f5w6fw6q 5141 29 , , , cord-006870-f5w6fw6q 5141 30 WFNS WFNS NNP cord-006870-f5w6fw6q 5141 31 1 1 CD cord-006870-f5w6fw6q 5141 32 ( ( -LRB- cord-006870-f5w6fw6q 5141 33 41 41 CD cord-006870-f5w6fw6q 5141 34 % % NN cord-006870-f5w6fw6q 5141 35 ) ) -RRB- cord-006870-f5w6fw6q 5141 36 and and CC cord-006870-f5w6fw6q 5141 37 Fisher Fisher NNP cord-006870-f5w6fw6q 5141 38 3 3 CD cord-006870-f5w6fw6q 5141 39 ( ( -LRB- cord-006870-f5w6fw6q 5141 40 48 48 CD cord-006870-f5w6fw6q 5141 41 % % NN cord-006870-f5w6fw6q 5141 42 ) ) -RRB- cord-006870-f5w6fw6q 5141 43 . . . cord-006870-f5w6fw6q 5142 1 Initial initial JJ cord-006870-f5w6fw6q 5142 2 and and CC cord-006870-f5w6fw6q 5142 3 peak peak NN cord-006870-f5w6fw6q 5142 4 plasma plasma NN cord-006870-f5w6fw6q 5143 1 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5143 2 concentrations concentration NNS cord-006870-f5w6fw6q 5143 3 were be VBD cord-006870-f5w6fw6q 5143 4 measured measure VBN cord-006870-f5w6fw6q 5143 5 in in IN cord-006870-f5w6fw6q 5143 6 268 268 CD cord-006870-f5w6fw6q 5143 7 plasma plasma NN cord-006870-f5w6fw6q 5143 8 samples sample NNS cord-006870-f5w6fw6q 5143 9 from from IN cord-006870-f5w6fw6q 5143 10 a a DT cord-006870-f5w6fw6q 5143 11 banked bank VBN cord-006870-f5w6fw6q 5143 12 biorepository biorepository NN cord-006870-f5w6fw6q 5143 13 using use VBG cord-006870-f5w6fw6q 5143 14 a a DT cord-006870-f5w6fw6q 5143 15 commercial commercial JJ cord-006870-f5w6fw6q 5143 16 sandwich sandwich NN cord-006870-f5w6fw6q 5143 17 solid solid JJ cord-006870-f5w6fw6q 5143 18 - - HYPH cord-006870-f5w6fw6q 5143 19 phase phase NN cord-006870-f5w6fw6q 5143 20 ELISA ELISA NNP cord-006870-f5w6fw6q 5143 21 kit kit NN cord-006870-f5w6fw6q 5143 22 . . . cord-006870-f5w6fw6q 5144 1 Delayed delay VBN cord-006870-f5w6fw6q 5144 2 neurological neurological JJ cord-006870-f5w6fw6q 5144 3 deterioration deterioration NN cord-006870-f5w6fw6q 5144 4 ( ( -LRB- cord-006870-f5w6fw6q 5144 5 DND DND NNP cord-006870-f5w6fw6q 5144 6 ) ) -RRB- cord-006870-f5w6fw6q 5144 7 and and CC cord-006870-f5w6fw6q 5144 8 delayed delay VBN cord-006870-f5w6fw6q 5144 9 cerebral cerebral JJ cord-006870-f5w6fw6q 5144 10 ischemia ischemia NN cord-006870-f5w6fw6q 5144 11 ( ( -LRB- cord-006870-f5w6fw6q 5144 12 DCI DCI NNP cord-006870-f5w6fw6q 5144 13 ) ) -RRB- cord-006870-f5w6fw6q 5144 14 were be VBD cord-006870-f5w6fw6q 5144 15 determined determine VBN cord-006870-f5w6fw6q 5144 16 using use VBG cord-006870-f5w6fw6q 5144 17 radiologic radiologic JJ cord-006870-f5w6fw6q 5144 18 and and CC cord-006870-f5w6fw6q 5144 19 clinical clinical JJ cord-006870-f5w6fw6q 5144 20 information information NN cord-006870-f5w6fw6q 5144 21 . . . cord-006870-f5w6fw6q 5145 1 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5145 2 levels level NNS cord-006870-f5w6fw6q 5145 3 were be VBD cord-006870-f5w6fw6q 5145 4 log log NN cord-006870-f5w6fw6q 5145 5 transformed transform VBN cord-006870-f5w6fw6q 5145 6 due due IN cord-006870-f5w6fw6q 5145 7 to to IN cord-006870-f5w6fw6q 5145 8 non non JJ cord-006870-f5w6fw6q 5145 9 - - JJ cord-006870-f5w6fw6q 5145 10 normality normality JJ cord-006870-f5w6fw6q 5145 11 . . . cord-006870-f5w6fw6q 5146 1 ANOVA ANOVA NNP cord-006870-f5w6fw6q 5146 2 , , , cord-006870-f5w6fw6q 5146 3 t t NNP cord-006870-f5w6fw6q 5146 4 - - HYPH cord-006870-f5w6fw6q 5146 5 Tests Tests NNP cord-006870-f5w6fw6q 5146 6 , , , cord-006870-f5w6fw6q 5146 7 Pearson Pearson NNP cord-006870-f5w6fw6q 5146 8 correlations correlation NNS cord-006870-f5w6fw6q 5146 9 and and CC cord-006870-f5w6fw6q 5146 10 logistic logistic JJ cord-006870-f5w6fw6q 5146 11 regression regression NN cord-006870-f5w6fw6q 5146 12 analyses analysis NNS cord-006870-f5w6fw6q 5146 13 were be VBD cord-006870-f5w6fw6q 5146 14 completed complete VBN cord-006870-f5w6fw6q 5146 15 using use VBG cord-006870-f5w6fw6q 5146 16 SPSS SPSS NNP cord-006870-f5w6fw6q 5146 17 and and CC cord-006870-f5w6fw6q 5146 18 SAS SAS NNP cord-006870-f5w6fw6q 5146 19 . . . cord-006870-f5w6fw6q 5147 1 Older old JJR cord-006870-f5w6fw6q 5147 2 age age NN cord-006870-f5w6fw6q 5147 3 was be VBD cord-006870-f5w6fw6q 5147 4 significantly significantly RB cord-006870-f5w6fw6q 5147 5 associated associate VBN cord-006870-f5w6fw6q 5147 6 with with IN cord-006870-f5w6fw6q 5147 7 lower low JJR cord-006870-f5w6fw6q 5147 8 initial initial JJ cord-006870-f5w6fw6q 5147 9 and and CC cord-006870-f5w6fw6q 5147 10 peak peak NN cord-006870-f5w6fw6q 5147 11 plasma plasma NN cord-006870-f5w6fw6q 5147 12 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5147 13 levels level NNS cord-006870-f5w6fw6q 5147 14 ( ( -LRB- cord-006870-f5w6fw6q 5147 15 r=.37 r=.37 CD cord-006870-f5w6fw6q 5147 16 , , , cord-006870-f5w6fw6q 5147 17 p<.001 p<.001 JJ cord-006870-f5w6fw6q 5147 18 ; ; : cord-006870-f5w6fw6q 5147 19 r=.41 r=.41 CD cord-006870-f5w6fw6q 5147 20 , , , cord-006870-f5w6fw6q 5147 21 p<.001 p<.001 NNP cord-006870-f5w6fw6q 5147 22 ) ) -RRB- cord-006870-f5w6fw6q 5147 23 . . . cord-006870-f5w6fw6q 5148 1 Men man NNS cord-006870-f5w6fw6q 5148 2 had have VBD cord-006870-f5w6fw6q 5148 3 higher high JJR cord-006870-f5w6fw6q 5148 4 initial initial JJ cord-006870-f5w6fw6q 5148 5 and and CC cord-006870-f5w6fw6q 5148 6 peak peak NN cord-006870-f5w6fw6q 5148 7 plasma plasma NN cord-006870-f5w6fw6q 5148 8 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5148 9 levels level NNS cord-006870-f5w6fw6q 5148 10 than than IN cord-006870-f5w6fw6q 5148 11 women woman NNS cord-006870-f5w6fw6q 5148 12 ( ( -LRB- cord-006870-f5w6fw6q 5148 13 p<.01 p<.01 NNP cord-006870-f5w6fw6q 5148 14 ; ; : cord-006870-f5w6fw6q 5148 15 p=.002 p=.002 NNP cord-006870-f5w6fw6q 5148 16 ) ) -RRB- cord-006870-f5w6fw6q 5148 17 , , , cord-006870-f5w6fw6q 5148 18 and and CC cord-006870-f5w6fw6q 5148 19 premenopausal premenopausal JJ cord-006870-f5w6fw6q 5148 20 women woman NNS cord-006870-f5w6fw6q 5148 21 had have VBD cord-006870-f5w6fw6q 5148 22 higher high JJR cord-006870-f5w6fw6q 5148 23 initial initial JJ cord-006870-f5w6fw6q 5148 24 and and CC cord-006870-f5w6fw6q 5148 25 peak peak NN cord-006870-f5w6fw6q 5148 26 plasma plasma NN cord-006870-f5w6fw6q 5149 1 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5149 2 levels level NNS cord-006870-f5w6fw6q 5149 3 than than IN cord-006870-f5w6fw6q 5149 4 post post JJ cord-006870-f5w6fw6q 5149 5 - - JJ cord-006870-f5w6fw6q 5149 6 menopausal menopausal JJ cord-006870-f5w6fw6q 5149 7 women woman NNS cord-006870-f5w6fw6q 5149 8 ( ( -LRB- cord-006870-f5w6fw6q 5149 9 p=.003 p=.003 NN cord-006870-f5w6fw6q 5149 10 ; ; : cord-006870-f5w6fw6q 5149 11 p=.004 p=.004 NNP cord-006870-f5w6fw6q 5149 12 ) ) -RRB- cord-006870-f5w6fw6q 5149 13 . . . cord-006870-f5w6fw6q 5150 1 Lower low JJR cord-006870-f5w6fw6q 5150 2 peak peak NN cord-006870-f5w6fw6q 5150 3 plasma plasma NN cord-006870-f5w6fw6q 5151 1 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5151 2 levels level NNS cord-006870-f5w6fw6q 5151 3 were be VBD cord-006870-f5w6fw6q 5151 4 associated associate VBN cord-006870-f5w6fw6q 5151 5 with with IN cord-006870-f5w6fw6q 5151 6 increased increase VBN cord-006870-f5w6fw6q 5151 7 clinical clinical JJ cord-006870-f5w6fw6q 5151 8 severity severity NN cord-006870-f5w6fw6q 5151 9 by by IN cord-006870-f5w6fw6q 5151 10 WFNS WFNS NNP cord-006870-f5w6fw6q 5151 11 ( ( -LRB- cord-006870-f5w6fw6q 5151 12 p=.02 p=.02 CD cord-006870-f5w6fw6q 5151 13 ) ) -RRB- cord-006870-f5w6fw6q 5151 14 and and CC cord-006870-f5w6fw6q 5151 15 Fisher Fisher NNP cord-006870-f5w6fw6q 5151 16 grade grade NN cord-006870-f5w6fw6q 5151 17 ( ( -LRB- cord-006870-f5w6fw6q 5151 18 p=.03 p=.03 NFP cord-006870-f5w6fw6q 5151 19 ) ) -RRB- cord-006870-f5w6fw6q 5151 20 as as RB cord-006870-f5w6fw6q 5151 21 well well RB cord-006870-f5w6fw6q 5151 22 as as IN cord-006870-f5w6fw6q 5151 23 the the DT cord-006870-f5w6fw6q 5151 24 development development NN cord-006870-f5w6fw6q 5151 25 of of IN cord-006870-f5w6fw6q 5151 26 DND DND NNP cord-006870-f5w6fw6q 5151 27 ( ( -LRB- cord-006870-f5w6fw6q 5151 28 p=.04 p=.04 NNP cord-006870-f5w6fw6q 5151 29 ; ; , cord-006870-f5w6fw6q 5151 30 p=.003 p=.003 NN cord-006870-f5w6fw6q 5151 31 ) ) -RRB- cord-006870-f5w6fw6q 5151 32 . . . cord-006870-f5w6fw6q 5152 1 Lower low JJR cord-006870-f5w6fw6q 5152 2 peak peak NN cord-006870-f5w6fw6q 5152 3 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5152 4 levels level NNS cord-006870-f5w6fw6q 5152 5 were be VBD cord-006870-f5w6fw6q 5152 6 associated associate VBN cord-006870-f5w6fw6q 5152 7 with with IN cord-006870-f5w6fw6q 5152 8 the the DT cord-006870-f5w6fw6q 5152 9 presence presence NN cord-006870-f5w6fw6q 5152 10 of of IN cord-006870-f5w6fw6q 5152 11 DCI DCI NNP cord-006870-f5w6fw6q 5152 12 ( ( -LRB- cord-006870-f5w6fw6q 5152 13 p=.009 p=.009 NNP cord-006870-f5w6fw6q 5152 14 ) ) -RRB- cord-006870-f5w6fw6q 5152 15 . . . cord-006870-f5w6fw6q 5153 1 Controlling control VBG cord-006870-f5w6fw6q 5153 2 for for IN cord-006870-f5w6fw6q 5153 3 age age NN cord-006870-f5w6fw6q 5153 4 and and CC cord-006870-f5w6fw6q 5153 5 Fisher Fisher NNP cord-006870-f5w6fw6q 5153 6 grade grade NN cord-006870-f5w6fw6q 5153 7 , , , cord-006870-f5w6fw6q 5153 8 log log NN cord-006870-f5w6fw6q 5153 9 peak peak NN cord-006870-f5w6fw6q 5153 10 plasma plasma NN cord-006870-f5w6fw6q 5153 11 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5153 12 levels level NNS cord-006870-f5w6fw6q 5153 13 remained remain VBD cord-006870-f5w6fw6q 5153 14 significantly significantly RB cord-006870-f5w6fw6q 5153 15 associated associate VBN cord-006870-f5w6fw6q 5153 16 with with IN cord-006870-f5w6fw6q 5153 17 the the DT cord-006870-f5w6fw6q 5153 18 presence presence NN cord-006870-f5w6fw6q 5153 19 of of IN cord-006870-f5w6fw6q 5153 20 DND DND NNP cord-006870-f5w6fw6q 5153 21 ( ( -LRB- cord-006870-f5w6fw6q 5153 22 p=.01 p=.01 NNP cord-006870-f5w6fw6q 5153 23 ; ; : cord-006870-f5w6fw6q 5153 24 OR or CC cord-006870-f5w6fw6q 5153 25 0.27 0.27 CD cord-006870-f5w6fw6q 5153 26 ; ; : cord-006870-f5w6fw6q 5153 27 CI ci NN cord-006870-f5w6fw6q 5153 28 : : : cord-006870-f5w6fw6q 5153 29 0.1-.74 0.1-.74 CD cord-006870-f5w6fw6q 5153 30 ) ) -RRB- cord-006870-f5w6fw6q 5153 31 and and CC cord-006870-f5w6fw6q 5153 32 DCI DCI NNP cord-006870-f5w6fw6q 5153 33 ( ( -LRB- cord-006870-f5w6fw6q 5153 34 p=.007 p=.007 NNS cord-006870-f5w6fw6q 5153 35 ; ; : cord-006870-f5w6fw6q 5153 36 OR or CC cord-006870-f5w6fw6q 5153 37 0.29 0.29 CD cord-006870-f5w6fw6q 5153 38 ; ; : cord-006870-f5w6fw6q 5153 39 CI ci NN cord-006870-f5w6fw6q 5153 40 : : : cord-006870-f5w6fw6q 5153 41 0.12 0.12 CD cord-006870-f5w6fw6q 5153 42 - - SYM cord-006870-f5w6fw6q 5153 43 0.7 0.7 CD cord-006870-f5w6fw6q 5153 44 ) ) -RRB- cord-006870-f5w6fw6q 5153 45 . . . cord-006870-f5w6fw6q 5154 1 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5154 2 levels level NNS cord-006870-f5w6fw6q 5154 3 have have VBP cord-006870-f5w6fw6q 5154 4 not not RB cord-006870-f5w6fw6q 5154 5 been be VBN cord-006870-f5w6fw6q 5154 6 well well RB cord-006870-f5w6fw6q 5154 7 characterized characterize VBN cord-006870-f5w6fw6q 5154 8 after after IN cord-006870-f5w6fw6q 5154 9 aSAH asah JJ cord-006870-f5w6fw6q 5154 10 . . . cord-006870-f5w6fw6q 5155 1 These these DT cord-006870-f5w6fw6q 5155 2 results result NNS cord-006870-f5w6fw6q 5155 3 suggest suggest VBP cord-006870-f5w6fw6q 5155 4 lower low JJR cord-006870-f5w6fw6q 5155 5 plasma plasma NN cord-006870-f5w6fw6q 5155 6 IGF1 IGF1 NNP cord-006870-f5w6fw6q 5155 7 are be VBP cord-006870-f5w6fw6q 5155 8 associated associate VBN cord-006870-f5w6fw6q 5155 9 with with IN cord-006870-f5w6fw6q 5155 10 clinical clinical JJ cord-006870-f5w6fw6q 5155 11 severity severity NN cord-006870-f5w6fw6q 5155 12 and and CC cord-006870-f5w6fw6q 5155 13 outcomes outcome NNS cord-006870-f5w6fw6q 5155 14 after after IN cord-006870-f5w6fw6q 5155 15 aSAH asah VBP cord-006870-f5w6fw6q 5155 16 and and CC cord-006870-f5w6fw6q 5155 17 provide provide VB cord-006870-f5w6fw6q 5155 18 impetus impetus NN cord-006870-f5w6fw6q 5155 19 for for IN cord-006870-f5w6fw6q 5155 20 future future JJ cord-006870-f5w6fw6q 5155 21 work work NN cord-006870-f5w6fw6q 5155 22 to to TO cord-006870-f5w6fw6q 5155 23 further further RB cord-006870-f5w6fw6q 5155 24 examine examine VB cord-006870-f5w6fw6q 5155 25 these these DT cord-006870-f5w6fw6q 5155 26 relationships relationship NNS cord-006870-f5w6fw6q 5155 27 . . . cord-006870-f5w6fw6q 5156 1 Induced induce VBN cord-006870-f5w6fw6q 5156 2 hypertension hypertension NN cord-006870-f5w6fw6q 5156 3 ( ( -LRB- cord-006870-f5w6fw6q 5156 4 IH IH NNP cord-006870-f5w6fw6q 5156 5 ) ) -RRB- cord-006870-f5w6fw6q 5156 6 is be VBZ cord-006870-f5w6fw6q 5156 7 the the DT cord-006870-f5w6fw6q 5156 8 mainstay mainstay NN cord-006870-f5w6fw6q 5156 9 of of IN cord-006870-f5w6fw6q 5156 10 medical medical JJ cord-006870-f5w6fw6q 5156 11 management management NN cord-006870-f5w6fw6q 5156 12 for for IN cord-006870-f5w6fw6q 5156 13 delayed delay VBN cord-006870-f5w6fw6q 5156 14 cerebral cerebral JJ cord-006870-f5w6fw6q 5156 15 ischemia ischemia NN cord-006870-f5w6fw6q 5156 16 ( ( -LRB- cord-006870-f5w6fw6q 5156 17 DCI DCI NNP cord-006870-f5w6fw6q 5156 18 ) ) -RRB- cord-006870-f5w6fw6q 5156 19 after after IN cord-006870-f5w6fw6q 5156 20 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5156 21 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5156 22 . . . cord-006870-f5w6fw6q 5157 1 However however RB cord-006870-f5w6fw6q 5157 2 , , , cord-006870-f5w6fw6q 5157 3 using use VBG cord-006870-f5w6fw6q 5157 4 vasopressors vasopressor NNS cord-006870-f5w6fw6q 5157 5 to to TO cord-006870-f5w6fw6q 5157 6 raise raise VB cord-006870-f5w6fw6q 5157 7 systemic systemic JJ cord-006870-f5w6fw6q 5157 8 blood blood NN cord-006870-f5w6fw6q 5157 9 pressure pressure NN cord-006870-f5w6fw6q 5157 10 well well RB cord-006870-f5w6fw6q 5157 11 above above IN cord-006870-f5w6fw6q 5157 12 normal normal JJ cord-006870-f5w6fw6q 5157 13 levels level NNS cord-006870-f5w6fw6q 5157 14 may may MD cord-006870-f5w6fw6q 5157 15 be be VB cord-006870-f5w6fw6q 5157 16 associated associate VBN cord-006870-f5w6fw6q 5157 17 with with IN cord-006870-f5w6fw6q 5157 18 systemic systemic JJ cord-006870-f5w6fw6q 5157 19 and and CC cord-006870-f5w6fw6q 5157 20 neurological neurological JJ cord-006870-f5w6fw6q 5157 21 complications complication NNS cord-006870-f5w6fw6q 5157 22 , , , cord-006870-f5w6fw6q 5157 23 of of IN cord-006870-f5w6fw6q 5157 24 which which WDT cord-006870-f5w6fw6q 5157 25 posterior posterior JJ cord-006870-f5w6fw6q 5157 26 reversible reversible JJ cord-006870-f5w6fw6q 5157 27 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5157 28 syndrome syndrome NN cord-006870-f5w6fw6q 5157 29 ( ( -LRB- cord-006870-f5w6fw6q 5157 30 PRES PRES NNP cord-006870-f5w6fw6q 5157 31 ) ) -RRB- cord-006870-f5w6fw6q 5157 32 has have VBZ cord-006870-f5w6fw6q 5157 33 been be VBN cord-006870-f5w6fw6q 5157 34 increasingly increasingly RB cord-006870-f5w6fw6q 5157 35 recognized recognize VBN cord-006870-f5w6fw6q 5157 36 . . . cord-006870-f5w6fw6q 5158 1 However however RB cord-006870-f5w6fw6q 5158 2 , , , cord-006870-f5w6fw6q 5158 3 the the DT cord-006870-f5w6fw6q 5158 4 frequency frequency NN cord-006870-f5w6fw6q 5158 5 and and CC cord-006870-f5w6fw6q 5158 6 risk risk NN cord-006870-f5w6fw6q 5158 7 factors factor NNS cord-006870-f5w6fw6q 5158 8 for for IN cord-006870-f5w6fw6q 5158 9 IH IH NNP cord-006870-f5w6fw6q 5158 10 - - HYPH cord-006870-f5w6fw6q 5158 11 induced induce VBN cord-006870-f5w6fw6q 5158 12 PRES PRES NNP cord-006870-f5w6fw6q 5158 13 have have VBP cord-006870-f5w6fw6q 5158 14 never never RB cord-006870-f5w6fw6q 5158 15 been be VBN cord-006870-f5w6fw6q 5158 16 systemically systemically RB cord-006870-f5w6fw6q 5158 17 evaluated evaluate VBN cord-006870-f5w6fw6q 5159 1 We -PRON- PRP cord-006870-f5w6fw6q 5159 2 identified identify VBD cord-006870-f5w6fw6q 5159 3 68 68 CD cord-006870-f5w6fw6q 5159 4 patients patient NNS cord-006870-f5w6fw6q 5159 5 treated treat VBN cord-006870-f5w6fw6q 5159 6 with with IN cord-006870-f5w6fw6q 5159 7 IH IH NNP cord-006870-f5w6fw6q 5159 8 from from IN cord-006870-f5w6fw6q 5159 9 345 345 CD cord-006870-f5w6fw6q 5159 10 SAH SAH NNP cord-006870-f5w6fw6q 5159 11 patients patient NNS cord-006870-f5w6fw6q 5159 12 admitted admit VBD cord-006870-f5w6fw6q 5159 13 over over IN cord-006870-f5w6fw6q 5159 14 a a DT cord-006870-f5w6fw6q 5159 15 three three CD cord-006870-f5w6fw6q 5159 16 - - HYPH cord-006870-f5w6fw6q 5159 17 year year NN cord-006870-f5w6fw6q 5159 18 period period NN cord-006870-f5w6fw6q 5159 19 . . . cord-006870-f5w6fw6q 5160 1 PRES PRES NNP cord-006870-f5w6fw6q 5160 2 was be VBD cord-006870-f5w6fw6q 5160 3 diagnosed diagnose VBN cord-006870-f5w6fw6q 5160 4 based base VBN cord-006870-f5w6fw6q 5160 5 on on IN cord-006870-f5w6fw6q 5160 6 clinical clinical JJ cord-006870-f5w6fw6q 5160 7 suspicion suspicion NN cord-006870-f5w6fw6q 5160 8 ( ( -LRB- cord-006870-f5w6fw6q 5160 9 i.e. i.e. FW cord-006870-f5w6fw6q 5160 10 unexplained unexplained JJ cord-006870-f5w6fw6q 5160 11 deterioration deterioration NN cord-006870-f5w6fw6q 5160 12 ) ) -RRB- cord-006870-f5w6fw6q 5160 13 , , , cord-006870-f5w6fw6q 5160 14 confirmed confirm VBN cord-006870-f5w6fw6q 5160 15 by by IN cord-006870-f5w6fw6q 5160 16 imaging image VBG cord-006870-f5w6fw6q 5160 17 . . . cord-006870-f5w6fw6q 5161 1 We -PRON- PRP cord-006870-f5w6fw6q 5161 2 conducted conduct VBD cord-006870-f5w6fw6q 5161 3 retrospective retrospective JJ cord-006870-f5w6fw6q 5161 4 extraction extraction NN cord-006870-f5w6fw6q 5161 5 of of IN cord-006870-f5w6fw6q 5161 6 data datum NNS cord-006870-f5w6fw6q 5161 7 on on IN cord-006870-f5w6fw6q 5161 8 IH IH NNP cord-006870-f5w6fw6q 5161 9 therapy therapy NN cord-006870-f5w6fw6q 5161 10 , , , cord-006870-f5w6fw6q 5161 11 including include VBG cord-006870-f5w6fw6q 5161 12 baseline baseline NN cord-006870-f5w6fw6q 5161 13 and and CC cord-006870-f5w6fw6q 5161 14 highest high JJS cord-006870-f5w6fw6q 5161 15 target target NN cord-006870-f5w6fw6q 5161 16 mean mean VBP cord-006870-f5w6fw6q 5161 17 arterial arterial JJ cord-006870-f5w6fw6q 5161 18 pressure pressure NN cord-006870-f5w6fw6q 5161 19 ( ( -LRB- cord-006870-f5w6fw6q 5161 20 MAP MAP NNP cord-006870-f5w6fw6q 5161 21 ) ) -RRB- cord-006870-f5w6fw6q 5161 22 and and CC cord-006870-f5w6fw6q 5161 23 vasopressor vasopressor NN cord-006870-f5w6fw6q 5161 24 dose dose NN cord-006870-f5w6fw6q 5161 25 / / SYM cord-006870-f5w6fw6q 5161 26 duration duration NN cord-006870-f5w6fw6q 5161 27 . . . cord-006870-f5w6fw6q 5162 1 We -PRON- PRP cord-006870-f5w6fw6q 5162 2 compared compare VBD cord-006870-f5w6fw6q 5162 3 those those DT cord-006870-f5w6fw6q 5162 4 with with IN cord-006870-f5w6fw6q 5162 5 PRES PRES NNP cord-006870-f5w6fw6q 5162 6 to to IN cord-006870-f5w6fw6q 5162 7 IHtreated IHtreated NNP cord-006870-f5w6fw6q 5162 8 controls control NNS cord-006870-f5w6fw6q 5162 9 and and CC cord-006870-f5w6fw6q 5162 10 also also RB cord-006870-f5w6fw6q 5162 11 described describe VBD cord-006870-f5w6fw6q 5162 12 the the DT cord-006870-f5w6fw6q 5162 13 clinical clinical JJ cord-006870-f5w6fw6q 5162 14 features feature NNS cord-006870-f5w6fw6q 5162 15 and and CC cord-006870-f5w6fw6q 5162 16 sequelae sequela NNS cord-006870-f5w6fw6q 5162 17 of of IN cord-006870-f5w6fw6q 5162 18 all all DT cord-006870-f5w6fw6q 5162 19 PRES PRES NNP cord-006870-f5w6fw6q 5162 20 cases case NNS cord-006870-f5w6fw6q 5162 21 . . . cord-006870-f5w6fw6q 5163 1 Five five CD cord-006870-f5w6fw6q 5163 2 SAH SAH NNP cord-006870-f5w6fw6q 5163 3 patients patient NNS cord-006870-f5w6fw6q 5163 4 were be VBD cord-006870-f5w6fw6q 5163 5 diagnosed diagnose VBN cord-006870-f5w6fw6q 5163 6 with with IN cord-006870-f5w6fw6q 5163 7 PRES PRES NNP cord-006870-f5w6fw6q 5163 8 , , , cord-006870-f5w6fw6q 5163 9 with with IN cord-006870-f5w6fw6q 5163 10 median median JJ cord-006870-f5w6fw6q 5163 11 time time NN cord-006870-f5w6fw6q 5163 12 from from IN cord-006870-f5w6fw6q 5163 13 initiation initiation NN cord-006870-f5w6fw6q 5163 14 of of IN cord-006870-f5w6fw6q 5163 15 vasopressors vasopressor NNS cord-006870-f5w6fw6q 5163 16 to to IN cord-006870-f5w6fw6q 5163 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 5163 18 of of IN cord-006870-f5w6fw6q 5163 19 6.6 6.6 CD cord-006870-f5w6fw6q 5163 20 days day NNS cord-006870-f5w6fw6q 5163 21 ( ( -LRB- cord-006870-f5w6fw6q 5163 22 range range NNP cord-006870-f5w6fw6q 5163 23 1 1 CD cord-006870-f5w6fw6q 5163 24 - - SYM cord-006870-f5w6fw6q 5163 25 8 8 CD cord-006870-f5w6fw6q 5163 26 days day NNS cord-006870-f5w6fw6q 5163 27 ) ) -RRB- cord-006870-f5w6fw6q 5163 28 . . . cord-006870-f5w6fw6q 5164 1 Baseline Baseline NNP cord-006870-f5w6fw6q 5164 2 MAP MAP NNP cord-006870-f5w6fw6q 5164 3 did do VBD cord-006870-f5w6fw6q 5164 4 not not RB cord-006870-f5w6fw6q 5164 5 differ differ VB cord-006870-f5w6fw6q 5164 6 between between IN cord-006870-f5w6fw6q 5164 7 PRES PRES NNP cord-006870-f5w6fw6q 5164 8 and and CC cord-006870-f5w6fw6q 5164 9 IH IH NNP cord-006870-f5w6fw6q 5164 10 controls control VBZ cord-006870-f5w6fw6q 5164 11 , , , cord-006870-f5w6fw6q 5164 12 but but CC cord-006870-f5w6fw6q 5164 13 highest high JJS cord-006870-f5w6fw6q 5164 14 target target NN cord-006870-f5w6fw6q 5164 15 MAP MAP NNP cord-006870-f5w6fw6q 5164 16 was be VBD cord-006870-f5w6fw6q 5164 17 greater great JJR cord-006870-f5w6fw6q 5165 1 ( ( -LRB- cord-006870-f5w6fw6q 5165 2 140 140 CD cord-006870-f5w6fw6q 5165 3 vs. vs. IN cord-006870-f5w6fw6q 5165 4 120 120 CD cord-006870-f5w6fw6q 5165 5 mm mm NN cord-006870-f5w6fw6q 5166 1 Hg hg NN cord-006870-f5w6fw6q 5166 2 , , , cord-006870-f5w6fw6q 5166 3 p=0.006 p=0.006 NNS cord-006870-f5w6fw6q 5166 4 ) ) -RRB- cord-006870-f5w6fw6q 5166 5 . . . cord-006870-f5w6fw6q 5167 1 Magnitude magnitude NN cord-006870-f5w6fw6q 5167 2 of of IN cord-006870-f5w6fw6q 5167 3 IH IH NNP cord-006870-f5w6fw6q 5167 4 was be VBD cord-006870-f5w6fw6q 5167 5 similarly similarly RB cord-006870-f5w6fw6q 5167 6 greater great JJR cord-006870-f5w6fw6q 5168 1 ( ( -LRB- cord-006870-f5w6fw6q 5168 2 54 54 CD cord-006870-f5w6fw6q 5168 3 vs. vs. NN cord-006870-f5w6fw6q 5168 4 34 34 CD cord-006870-f5w6fw6q 5168 5 mm mm CD cord-006870-f5w6fw6q 5168 6 Hg hg NN cord-006870-f5w6fw6q 5168 7 above above IN cord-006870-f5w6fw6q 5168 8 baseline baseline NN cord-006870-f5w6fw6q 5168 9 , , , cord-006870-f5w6fw6q 5168 10 p=0.004 p=0.004 NNP cord-006870-f5w6fw6q 5168 11 ) ) -RRB- cord-006870-f5w6fw6q 5168 12 . . . cord-006870-f5w6fw6q 5169 1 All all DT cord-006870-f5w6fw6q 5169 2 cases case NNS cord-006870-f5w6fw6q 5169 3 presented present VBN cord-006870-f5w6fw6q 5169 4 with with IN cord-006870-f5w6fw6q 5169 5 lethargy lethargy NN cord-006870-f5w6fw6q 5169 6 , , , cord-006870-f5w6fw6q 5169 7 three three CD cord-006870-f5w6fw6q 5169 8 had have VBD cord-006870-f5w6fw6q 5169 9 new new JJ cord-006870-f5w6fw6q 5169 10 focal focal JJ cord-006870-f5w6fw6q 5169 11 deficits deficit NNS cord-006870-f5w6fw6q 5169 12 , , , cord-006870-f5w6fw6q 5169 13 and and CC cord-006870-f5w6fw6q 5169 14 one one CD cord-006870-f5w6fw6q 5169 15 had have VBD cord-006870-f5w6fw6q 5169 16 a a DT cord-006870-f5w6fw6q 5169 17 seizure seizure NN cord-006870-f5w6fw6q 5169 18 . . . cord-006870-f5w6fw6q 5170 1 One one CD cord-006870-f5w6fw6q 5170 2 died die VBD cord-006870-f5w6fw6q 5170 3 from from IN cord-006870-f5w6fw6q 5170 4 cardiac cardiac JJ cord-006870-f5w6fw6q 5170 5 complications complication NNS cord-006870-f5w6fw6q 5170 6 but but CC cord-006870-f5w6fw6q 5170 7 the the DT cord-006870-f5w6fw6q 5170 8 other other JJ cord-006870-f5w6fw6q 5170 9 four four CD cord-006870-f5w6fw6q 5170 10 patients patient NNS cord-006870-f5w6fw6q 5170 11 had have VBD cord-006870-f5w6fw6q 5170 12 complete complete JJ cord-006870-f5w6fw6q 5170 13 resolution resolution NN cord-006870-f5w6fw6q 5170 14 with with IN cord-006870-f5w6fw6q 5170 15 IH IH NNP cord-006870-f5w6fw6q 5170 16 discontinuation discontinuation NN cord-006870-f5w6fw6q 5170 17 , , , cord-006870-f5w6fw6q 5170 18 without without IN cord-006870-f5w6fw6q 5170 19 infarction infarction NN cord-006870-f5w6fw6q 5170 20 or or CC cord-006870-f5w6fw6q 5170 21 residual residual JJ cord-006870-f5w6fw6q 5170 22 disability disability NN cord-006870-f5w6fw6q 5170 23 . . . cord-006870-f5w6fw6q 5171 1 PRES PRES NNP cord-006870-f5w6fw6q 5171 2 was be VBD cord-006870-f5w6fw6q 5171 3 diagnosed diagnose VBN cord-006870-f5w6fw6q 5171 4 in in IN cord-006870-f5w6fw6q 5171 5 7 7 CD cord-006870-f5w6fw6q 5171 6 % % NN cord-006870-f5w6fw6q 5171 7 of of IN cord-006870-f5w6fw6q 5171 8 patients patient NNS cord-006870-f5w6fw6q 5171 9 undergoing undergo VBG cord-006870-f5w6fw6q 5171 10 IH IH NNP cord-006870-f5w6fw6q 5171 11 therapy therapy NN cord-006870-f5w6fw6q 5171 12 and and CC cord-006870-f5w6fw6q 5171 13 was be VBD cord-006870-f5w6fw6q 5171 14 most most RBS cord-006870-f5w6fw6q 5171 15 likely likely JJ cord-006870-f5w6fw6q 5171 16 when when WRB cord-006870-f5w6fw6q 5171 17 MAP MAP NNP cord-006870-f5w6fw6q 5171 18 was be VBD cord-006870-f5w6fw6q 5171 19 raised raise VBN cord-006870-f5w6fw6q 5171 20 well well RB cord-006870-f5w6fw6q 5171 21 above above IN cord-006870-f5w6fw6q 5171 22 baseline baseline NN cord-006870-f5w6fw6q 5171 23 to to IN cord-006870-f5w6fw6q 5171 24 levels level NNS cord-006870-f5w6fw6q 5171 25 exceeding exceed VBG cord-006870-f5w6fw6q 5171 26 the the DT cord-006870-f5w6fw6q 5171 27 traditional traditional JJ cord-006870-f5w6fw6q 5171 28 limits limit NNS cord-006870-f5w6fw6q 5171 29 of of IN cord-006870-f5w6fw6q 5171 30 autoregulation autoregulation NN cord-006870-f5w6fw6q 5171 31 ( ( -LRB- cord-006870-f5w6fw6q 5171 32 130 130 CD cord-006870-f5w6fw6q 5171 33 - - SYM cord-006870-f5w6fw6q 5171 34 140 140 CD cord-006870-f5w6fw6q 5171 35 mm mm CD cord-006870-f5w6fw6q 5171 36 Hg Hg NNP cord-006870-f5w6fw6q 5171 37 ) ) -RRB- cord-006870-f5w6fw6q 5171 38 . . . cord-006870-f5w6fw6q 5172 1 High high JJ cord-006870-f5w6fw6q 5172 2 clinical clinical JJ cord-006870-f5w6fw6q 5172 3 suspicion suspicion NN cord-006870-f5w6fw6q 5172 4 for for IN cord-006870-f5w6fw6q 5172 5 this this DT cord-006870-f5w6fw6q 5172 6 reversible reversible JJ cord-006870-f5w6fw6q 5172 7 disorder disorder NN cord-006870-f5w6fw6q 5172 8 appears appear VBZ cord-006870-f5w6fw6q 5172 9 warranted warrant VBN cord-006870-f5w6fw6q 5172 10 when when WRB cord-006870-f5w6fw6q 5172 11 aggressive aggressive JJ cord-006870-f5w6fw6q 5172 12 IH IH NNP cord-006870-f5w6fw6q 5172 13 targets target NNS cord-006870-f5w6fw6q 5172 14 are be VBP cord-006870-f5w6fw6q 5172 15 maintained maintain VBN cord-006870-f5w6fw6q 5172 16 for for IN cord-006870-f5w6fw6q 5172 17 several several JJ cord-006870-f5w6fw6q 5172 18 days day NNS cord-006870-f5w6fw6q 5172 19 or or CC cord-006870-f5w6fw6q 5172 20 in in IN cord-006870-f5w6fw6q 5172 21 the the DT cord-006870-f5w6fw6q 5172 22 presence presence NN cord-006870-f5w6fw6q 5172 23 of of IN cord-006870-f5w6fw6q 5172 24 unexplained unexplained JJ cord-006870-f5w6fw6q 5172 25 neurological neurological JJ cord-006870-f5w6fw6q 5172 26 deterioration deterioration NN cord-006870-f5w6fw6q 5172 27 . . . cord-006870-f5w6fw6q 5173 1 Other other JJ cord-006870-f5w6fw6q 5173 2 interventions intervention NNS cord-006870-f5w6fw6q 5173 3 may may MD cord-006870-f5w6fw6q 5173 4 be be VB cord-006870-f5w6fw6q 5173 5 preferable preferable JJ cord-006870-f5w6fw6q 5173 6 for for IN cord-006870-f5w6fw6q 5173 7 refractory refractory JJ cord-006870-f5w6fw6q 5173 8 DCI DCI NNP cord-006870-f5w6fw6q 5173 9 when when WRB cord-006870-f5w6fw6q 5173 10 moderate moderate JJ cord-006870-f5w6fw6q 5173 11 degrees degree NNS cord-006870-f5w6fw6q 5173 12 of of IN cord-006870-f5w6fw6q 5173 13 IH IH NNP cord-006870-f5w6fw6q 5173 14 have have VBP cord-006870-f5w6fw6q 5173 15 been be VBN cord-006870-f5w6fw6q 5173 16 attempted attempt VBN cord-006870-f5w6fw6q 5173 17 . . . cord-006870-f5w6fw6q 5174 1 Patients patient NNS cord-006870-f5w6fw6q 5174 2 with with IN cord-006870-f5w6fw6q 5174 3 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 5174 4 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5174 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5174 6 ( ( -LRB- cord-006870-f5w6fw6q 5174 7 aSAH asah JJ cord-006870-f5w6fw6q 5174 8 ) ) -RRB- cord-006870-f5w6fw6q 5174 9 may may MD cord-006870-f5w6fw6q 5174 10 receive receive VB cord-006870-f5w6fw6q 5174 11 significant significant JJ cord-006870-f5w6fw6q 5174 12 exposure exposure NN cord-006870-f5w6fw6q 5174 13 to to IN cord-006870-f5w6fw6q 5174 14 potentially potentially RB cord-006870-f5w6fw6q 5174 15 harmful harmful JJ cord-006870-f5w6fw6q 5174 16 ionizing ionize VBG cord-006870-f5w6fw6q 5174 17 radiation radiation NN cord-006870-f5w6fw6q 5174 18 exposure exposure NN cord-006870-f5w6fw6q 5174 19 ( ( -LRB- cord-006870-f5w6fw6q 5174 20 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5174 21 ) ) -RRB- cord-006870-f5w6fw6q 5174 22 from from IN cord-006870-f5w6fw6q 5174 23 diagnostic diagnostic JJ cord-006870-f5w6fw6q 5174 24 tests test NNS cord-006870-f5w6fw6q 5174 25 and and CC cord-006870-f5w6fw6q 5174 26 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5174 27 procedures procedure NNS cord-006870-f5w6fw6q 5174 28 during during IN cord-006870-f5w6fw6q 5174 29 their -PRON- PRP$ cord-006870-f5w6fw6q 5174 30 initial initial JJ cord-006870-f5w6fw6q 5174 31 hospitalization hospitalization NN cord-006870-f5w6fw6q 5174 32 . . . cord-006870-f5w6fw6q 5175 1 We -PRON- PRP cord-006870-f5w6fw6q 5175 2 hypothesized hypothesize VBD cord-006870-f5w6fw6q 5175 3 that that IN cord-006870-f5w6fw6q 5175 4 risk risk NN cord-006870-f5w6fw6q 5175 5 factors factor NNS cord-006870-f5w6fw6q 5175 6 to to TO cord-006870-f5w6fw6q 5175 7 detect detect VB cord-006870-f5w6fw6q 5175 8 excessive excessive JJ cord-006870-f5w6fw6q 5175 9 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5175 10 are be VBP cord-006870-f5w6fw6q 5175 11 present present JJ cord-006870-f5w6fw6q 5175 12 at at IN cord-006870-f5w6fw6q 5175 13 the the DT cord-006870-f5w6fw6q 5175 14 time time NN cord-006870-f5w6fw6q 5175 15 of of IN cord-006870-f5w6fw6q 5175 16 admission admission NN cord-006870-f5w6fw6q 5175 17 . . . cord-006870-f5w6fw6q 5176 1 Following follow VBG cord-006870-f5w6fw6q 5176 2 IRB IRB NNP cord-006870-f5w6fw6q 5176 3 approval approval NN cord-006870-f5w6fw6q 5176 4 , , , cord-006870-f5w6fw6q 5176 5 all all DT cord-006870-f5w6fw6q 5176 6 patients patient NNS cord-006870-f5w6fw6q 5176 7 admitted admit VBN cord-006870-f5w6fw6q 5176 8 to to IN cord-006870-f5w6fw6q 5176 9 our -PRON- PRP$ cord-006870-f5w6fw6q 5176 10 institution institution NN cord-006870-f5w6fw6q 5176 11 with with IN cord-006870-f5w6fw6q 5176 12 documented document VBN cord-006870-f5w6fw6q 5176 13 aSAH asah JJ cord-006870-f5w6fw6q 5176 14 over over IN cord-006870-f5w6fw6q 5176 15 a a DT cord-006870-f5w6fw6q 5176 16 4-year 4-year CD cord-006870-f5w6fw6q 5176 17 period period NN cord-006870-f5w6fw6q 5176 18 were be VBD cord-006870-f5w6fw6q 5176 19 retrospectively retrospectively RB cord-006870-f5w6fw6q 5176 20 evaluated evaluate VBN cord-006870-f5w6fw6q 5176 21 for for IN cord-006870-f5w6fw6q 5176 22 inclusion inclusion NN cord-006870-f5w6fw6q 5176 23 and and CC cord-006870-f5w6fw6q 5176 24 exclusion exclusion NN cord-006870-f5w6fw6q 5176 25 criteria criterion NNS cord-006870-f5w6fw6q 5176 26 . . . cord-006870-f5w6fw6q 5177 1 Patients patient NNS cord-006870-f5w6fw6q 5177 2 were be VBD cord-006870-f5w6fw6q 5177 3 excluded exclude VBN cord-006870-f5w6fw6q 5177 4 if if IN cord-006870-f5w6fw6q 5177 5 they -PRON- PRP cord-006870-f5w6fw6q 5177 6 died die VBD cord-006870-f5w6fw6q 5177 7 prior prior RB cord-006870-f5w6fw6q 5177 8 to to IN cord-006870-f5w6fw6q 5177 9 discharge discharge NN cord-006870-f5w6fw6q 5177 10 . . . cord-006870-f5w6fw6q 5178 1 All all DT cord-006870-f5w6fw6q 5178 2 study study NN cord-006870-f5w6fw6q 5178 3 data datum NNS cord-006870-f5w6fw6q 5178 4 , , , cord-006870-f5w6fw6q 5178 5 including include VBG cord-006870-f5w6fw6q 5178 6 SAH sah NN cord-006870-f5w6fw6q 5178 7 - - HYPH cord-006870-f5w6fw6q 5178 8 specific specific JJ cord-006870-f5w6fw6q 5178 9 and and CC cord-006870-f5w6fw6q 5178 10 patient patient JJ cord-006870-f5w6fw6q 5178 11 - - HYPH cord-006870-f5w6fw6q 5178 12 specific specific JJ cord-006870-f5w6fw6q 5178 13 risk risk NN cord-006870-f5w6fw6q 5178 14 factors factor NNS cord-006870-f5w6fw6q 5178 15 , , , cord-006870-f5w6fw6q 5178 16 were be VBD cord-006870-f5w6fw6q 5178 17 obtained obtain VBN cord-006870-f5w6fw6q 5178 18 from from IN cord-006870-f5w6fw6q 5178 19 the the DT cord-006870-f5w6fw6q 5178 20 electronic electronic JJ cord-006870-f5w6fw6q 5178 21 medical medical JJ cord-006870-f5w6fw6q 5178 22 record record NN cord-006870-f5w6fw6q 5178 23 . . . cord-006870-f5w6fw6q 5179 1 The the DT cord-006870-f5w6fw6q 5179 2 total total JJ cord-006870-f5w6fw6q 5179 3 effective effective JJ cord-006870-f5w6fw6q 5179 4 dose dose NN cord-006870-f5w6fw6q 5179 5 of of IN cord-006870-f5w6fw6q 5179 6 ionizing ionize VBG cord-006870-f5w6fw6q 5179 7 radiation radiation NN cord-006870-f5w6fw6q 5179 8 ( ( -LRB- cord-006870-f5w6fw6q 5179 9 TEDIR TEDIR NNP cord-006870-f5w6fw6q 5179 10 ) ) -RRB- cord-006870-f5w6fw6q 5179 11 per per IN cord-006870-f5w6fw6q 5179 12 patient patient NN cord-006870-f5w6fw6q 5179 13 was be VBD cord-006870-f5w6fw6q 5179 14 calculated calculate VBN cord-006870-f5w6fw6q 5179 15 from from IN cord-006870-f5w6fw6q 5179 16 previously previously RB cord-006870-f5w6fw6q 5179 17 published publish VBN cord-006870-f5w6fw6q 5179 18 radiation radiation NN cord-006870-f5w6fw6q 5179 19 exposure exposure NN cord-006870-f5w6fw6q 5179 20 data datum NNS cord-006870-f5w6fw6q 5179 21 . . . cord-006870-f5w6fw6q 5180 1 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5180 2 was be VBD cord-006870-f5w6fw6q 5180 3 considered consider VBN cord-006870-f5w6fw6q 5180 4 to to TO cord-006870-f5w6fw6q 5180 5 have have VB cord-006870-f5w6fw6q 5180 6 occurred occur VBN cord-006870-f5w6fw6q 5180 7 if if IN cord-006870-f5w6fw6q 5180 8 TEDIR TEDIR NNP cord-006870-f5w6fw6q 5180 9 was be VBD cord-006870-f5w6fw6q 5180 10 greater great JJR cord-006870-f5w6fw6q 5180 11 than than IN cord-006870-f5w6fw6q 5180 12 50 50 CD cord-006870-f5w6fw6q 5180 13 mSV mSV NNP cord-006870-f5w6fw6q 5180 14 , , , cord-006870-f5w6fw6q 5180 15 the the DT cord-006870-f5w6fw6q 5180 16 annual annual JJ cord-006870-f5w6fw6q 5180 17 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5180 18 limit limit NN cord-006870-f5w6fw6q 5180 19 for for IN cord-006870-f5w6fw6q 5180 20 radiation radiation NN cord-006870-f5w6fw6q 5180 21 workers worker NNS cord-006870-f5w6fw6q 5180 22 . . . cord-006870-f5w6fw6q 5181 1 Logistic logistic JJ cord-006870-f5w6fw6q 5181 2 regression regression NN cord-006870-f5w6fw6q 5181 3 models model NNS cord-006870-f5w6fw6q 5181 4 were be VBD cord-006870-f5w6fw6q 5181 5 then then RB cord-006870-f5w6fw6q 5181 6 fit fit JJ cord-006870-f5w6fw6q 5181 7 to to IN cord-006870-f5w6fw6q 5181 8 the the DT cord-006870-f5w6fw6q 5181 9 dataset dataset NN cord-006870-f5w6fw6q 5181 10 to to TO cord-006870-f5w6fw6q 5181 11 evaluate evaluate VB cord-006870-f5w6fw6q 5181 12 clinical clinical JJ cord-006870-f5w6fw6q 5181 13 variables variable NNS cord-006870-f5w6fw6q 5181 14 that that WDT cord-006870-f5w6fw6q 5181 15 significantly significantly RB cord-006870-f5w6fw6q 5181 16 the the DT cord-006870-f5w6fw6q 5181 17 risk risk NN cord-006870-f5w6fw6q 5181 18 of of IN cord-006870-f5w6fw6q 5181 19 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5181 20 in in IN cord-006870-f5w6fw6q 5181 21 these these DT cord-006870-f5w6fw6q 5181 22 patients patient NNS cord-006870-f5w6fw6q 5181 23 . . . cord-006870-f5w6fw6q 5182 1 Data datum NNS cord-006870-f5w6fw6q 5182 2 were be VBD cord-006870-f5w6fw6q 5182 3 collected collect VBN cord-006870-f5w6fw6q 5182 4 from from IN cord-006870-f5w6fw6q 5182 5 108 108 CD cord-006870-f5w6fw6q 5182 6 patients patient NNS cord-006870-f5w6fw6q 5182 7 ( ( -LRB- cord-006870-f5w6fw6q 5182 8 58.4 58.4 CD cord-006870-f5w6fw6q 5182 9 % % NN cord-006870-f5w6fw6q 5182 10 of of IN cord-006870-f5w6fw6q 5182 11 all all DT cord-006870-f5w6fw6q 5182 12 aSAH asah JJ cord-006870-f5w6fw6q 5182 13 patients patient NNS cord-006870-f5w6fw6q 5182 14 evaluated evaluate VBN cord-006870-f5w6fw6q 5182 15 ) ) -RRB- cord-006870-f5w6fw6q 5182 16 . . . cord-006870-f5w6fw6q 5183 1 The the DT cord-006870-f5w6fw6q 5183 2 mean mean JJ cord-006870-f5w6fw6q 5183 3 TEDIR TEDIR NNP cord-006870-f5w6fw6q 5183 4 in in IN cord-006870-f5w6fw6q 5183 5 these these DT cord-006870-f5w6fw6q 5183 6 patients patient NNS cord-006870-f5w6fw6q 5183 7 was be VBD cord-006870-f5w6fw6q 5183 8 47.8 47.8 CD cord-006870-f5w6fw6q 5183 9 mSv mSv NNP cord-006870-f5w6fw6q 5183 10 . . . cord-006870-f5w6fw6q 5184 1 Forty forty CD cord-006870-f5w6fw6q 5184 2 - - HYPH cord-006870-f5w6fw6q 5184 3 two two CD cord-006870-f5w6fw6q 5184 4 ( ( -LRB- cord-006870-f5w6fw6q 5184 5 38.9 38.9 CD cord-006870-f5w6fw6q 5184 6 % % NN cord-006870-f5w6fw6q 5184 7 ) ) -RRB- cord-006870-f5w6fw6q 5184 8 of of IN cord-006870-f5w6fw6q 5184 9 patients patient NNS cord-006870-f5w6fw6q 5184 10 met meet VBD cord-006870-f5w6fw6q 5184 11 criteria criterion NNS cord-006870-f5w6fw6q 5184 12 for for IN cord-006870-f5w6fw6q 5184 13 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5184 14 . . . cord-006870-f5w6fw6q 5185 1 In in IN cord-006870-f5w6fw6q 5185 2 multivariate multivariate JJ cord-006870-f5w6fw6q 5185 3 logistic logistic JJ cord-006870-f5w6fw6q 5185 4 regression regression NN cord-006870-f5w6fw6q 5185 5 modeling modeling NN cord-006870-f5w6fw6q 5185 6 , , , cord-006870-f5w6fw6q 5185 7 male male JJ cord-006870-f5w6fw6q 5185 8 gender gender NN cord-006870-f5w6fw6q 5185 9 ( ( -LRB- cord-006870-f5w6fw6q 5185 10 OR=3.2 OR=3.2 NNP cord-006870-f5w6fw6q 5185 11 , , , cord-006870-f5w6fw6q 5185 12 CI=1.1 ci=1.1 NN cord-006870-f5w6fw6q 5185 13 - - HYPH cord-006870-f5w6fw6q 5185 14 11.8 11.8 CD cord-006870-f5w6fw6q 5185 15 ) ) -RRB- cord-006870-f5w6fw6q 5185 16 , , , cord-006870-f5w6fw6q 5185 17 posterior posterior JJ cord-006870-f5w6fw6q 5185 18 circulation circulation NN cord-006870-f5w6fw6q 5185 19 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5185 20 ( ( -LRB- cord-006870-f5w6fw6q 5185 21 OR=3.7 OR=3.7 NNP cord-006870-f5w6fw6q 5185 22 , , , cord-006870-f5w6fw6q 5185 23 CI=1.2 ci=1.2 NN cord-006870-f5w6fw6q 5185 24 - - HYPH cord-006870-f5w6fw6q 5185 25 11.5 11.5 CD cord-006870-f5w6fw6q 5185 26 ) ) -RRB- cord-006870-f5w6fw6q 5185 27 and and CC cord-006870-f5w6fw6q 5185 28 ventriculostomy ventriculostomy NNP cord-006870-f5w6fw6q 5185 29 ( ( -LRB- cord-006870-f5w6fw6q 5185 30 OR=24.8 or=24.8 UH cord-006870-f5w6fw6q 5185 31 , , , cord-006870-f5w6fw6q 5185 32 CI=3.7 ci=3.7 NN cord-006870-f5w6fw6q 5185 33 - - HYPH cord-006870-f5w6fw6q 5185 34 164.7 164.7 CD cord-006870-f5w6fw6q 5185 35 ) ) -RRB- cord-006870-f5w6fw6q 5185 36 were be VBD cord-006870-f5w6fw6q 5185 37 significantly significantly RB cord-006870-f5w6fw6q 5185 38 associated associate VBN cord-006870-f5w6fw6q 5185 39 with with IN cord-006870-f5w6fw6q 5185 40 an an DT cord-006870-f5w6fw6q 5185 41 increased increase VBN cord-006870-f5w6fw6q 5185 42 risk risk NN cord-006870-f5w6fw6q 5185 43 of of IN cord-006870-f5w6fw6q 5185 44 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5185 45 . . . cord-006870-f5w6fw6q 5186 1 In in IN cord-006870-f5w6fw6q 5186 2 this this DT cord-006870-f5w6fw6q 5186 3 study study NN cord-006870-f5w6fw6q 5186 4 , , , cord-006870-f5w6fw6q 5186 5 approximately approximately RB cord-006870-f5w6fw6q 5186 6 40 40 CD cord-006870-f5w6fw6q 5186 7 % % NN cord-006870-f5w6fw6q 5186 8 of of IN cord-006870-f5w6fw6q 5186 9 aSAH asah JJ cord-006870-f5w6fw6q 5186 10 patients patient NNS cord-006870-f5w6fw6q 5186 11 received receive VBD cord-006870-f5w6fw6q 5186 12 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5186 13 . . . cord-006870-f5w6fw6q 5187 1 Male male JJ cord-006870-f5w6fw6q 5187 2 gender gender NN cord-006870-f5w6fw6q 5187 3 , , , cord-006870-f5w6fw6q 5187 4 posterior posterior JJ cord-006870-f5w6fw6q 5187 5 circulation circulation NN cord-006870-f5w6fw6q 5187 6 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5187 7 and and CC cord-006870-f5w6fw6q 5187 8 ventriculostomy ventriculostomy NN cord-006870-f5w6fw6q 5187 9 were be VBD cord-006870-f5w6fw6q 5187 10 significantly significantly RB cord-006870-f5w6fw6q 5187 11 associated associate VBN cord-006870-f5w6fw6q 5187 12 with with IN cord-006870-f5w6fw6q 5187 13 increased increase VBN cord-006870-f5w6fw6q 5187 14 risk risk NN cord-006870-f5w6fw6q 5187 15 of of IN cord-006870-f5w6fw6q 5187 16 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5187 17 . . . cord-006870-f5w6fw6q 5188 1 These these DT cord-006870-f5w6fw6q 5188 2 factors factor NNS cord-006870-f5w6fw6q 5188 3 may may MD cord-006870-f5w6fw6q 5188 4 serve serve VB cord-006870-f5w6fw6q 5188 5 as as IN cord-006870-f5w6fw6q 5188 6 important important JJ cord-006870-f5w6fw6q 5188 7 predictors predictor NNS cord-006870-f5w6fw6q 5188 8 of of IN cord-006870-f5w6fw6q 5188 9 patients patient NNS cord-006870-f5w6fw6q 5188 10 who who WP cord-006870-f5w6fw6q 5188 11 require require VBP cord-006870-f5w6fw6q 5188 12 additional additional JJ cord-006870-f5w6fw6q 5188 13 or or CC cord-006870-f5w6fw6q 5188 14 complex complex JJ cord-006870-f5w6fw6q 5188 15 care care NN cord-006870-f5w6fw6q 5188 16 necessitating necessitate VBG cord-006870-f5w6fw6q 5188 17 repeated repeat VBN cord-006870-f5w6fw6q 5188 18 diagnostic diagnostic JJ cord-006870-f5w6fw6q 5188 19 or or CC cord-006870-f5w6fw6q 5188 20 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5188 21 procedures procedure NNS cord-006870-f5w6fw6q 5188 22 during during IN cord-006870-f5w6fw6q 5188 23 their -PRON- PRP$ cord-006870-f5w6fw6q 5188 24 hospitalization hospitalization NN cord-006870-f5w6fw6q 5188 25 . . . cord-006870-f5w6fw6q 5189 1 Alternative alternative JJ cord-006870-f5w6fw6q 5189 2 diagnostic diagnostic JJ cord-006870-f5w6fw6q 5189 3 or or CC cord-006870-f5w6fw6q 5189 4 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5189 5 modalities modality NNS cord-006870-f5w6fw6q 5189 6 should should MD cord-006870-f5w6fw6q 5189 7 be be VB cord-006870-f5w6fw6q 5189 8 considered consider VBN cord-006870-f5w6fw6q 5189 9 for for IN cord-006870-f5w6fw6q 5189 10 patients patient NNS cord-006870-f5w6fw6q 5189 11 with with IN cord-006870-f5w6fw6q 5189 12 these these DT cord-006870-f5w6fw6q 5189 13 risk risk NN cord-006870-f5w6fw6q 5189 14 factors factor NNS cord-006870-f5w6fw6q 5189 15 to to TO cord-006870-f5w6fw6q 5189 16 limit limit VB cord-006870-f5w6fw6q 5189 17 the the DT cord-006870-f5w6fw6q 5189 18 risk risk NN cord-006870-f5w6fw6q 5189 19 of of IN cord-006870-f5w6fw6q 5189 20 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5189 21 . . . cord-006870-f5w6fw6q 5190 1 Future future JJ cord-006870-f5w6fw6q 5190 2 research research NN cord-006870-f5w6fw6q 5190 3 should should MD cord-006870-f5w6fw6q 5190 4 also also RB cord-006870-f5w6fw6q 5190 5 evaluate evaluate VB cord-006870-f5w6fw6q 5190 6 the the DT cord-006870-f5w6fw6q 5190 7 effect effect NN cord-006870-f5w6fw6q 5190 8 of of IN cord-006870-f5w6fw6q 5190 9 PHIRE PHIRE NNP cord-006870-f5w6fw6q 5190 10 on on IN cord-006870-f5w6fw6q 5190 11 neurologic neurologic JJ cord-006870-f5w6fw6q 5190 12 outcomes outcome NNS cord-006870-f5w6fw6q 5190 13 in in IN cord-006870-f5w6fw6q 5190 14 these these DT cord-006870-f5w6fw6q 5190 15 patients patient NNS cord-006870-f5w6fw6q 5190 16 . . . cord-006870-f5w6fw6q 5191 1 It -PRON- PRP cord-006870-f5w6fw6q 5191 2 remains remain VBZ cord-006870-f5w6fw6q 5191 3 unclear unclear JJ cord-006870-f5w6fw6q 5191 4 whether whether IN cord-006870-f5w6fw6q 5191 5 patients patient NNS cord-006870-f5w6fw6q 5191 6 with with IN cord-006870-f5w6fw6q 5191 7 unruptured unruptured JJ cord-006870-f5w6fw6q 5191 8 intracranial intracranial JJ cord-006870-f5w6fw6q 5191 9 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5191 10 ( ( -LRB- cord-006870-f5w6fw6q 5191 11 ICA ICA NNP cord-006870-f5w6fw6q 5191 12 ) ) -RRB- cord-006870-f5w6fw6q 5191 13 should should MD cord-006870-f5w6fw6q 5191 14 be be VB cord-006870-f5w6fw6q 5191 15 treated treat VBN cord-006870-f5w6fw6q 5191 16 . . . cord-006870-f5w6fw6q 5192 1 Vessel vessel NN cord-006870-f5w6fw6q 5192 2 wall wall NN cord-006870-f5w6fw6q 5192 3 enhancement enhancement NN cord-006870-f5w6fw6q 5192 4 ( ( -LRB- cord-006870-f5w6fw6q 5192 5 VWE VWE NNP cord-006870-f5w6fw6q 5192 6 ) ) -RRB- cord-006870-f5w6fw6q 5192 7 in in IN cord-006870-f5w6fw6q 5192 8 high high JJ cord-006870-f5w6fw6q 5192 9 - - HYPH cord-006870-f5w6fw6q 5192 10 resolution resolution NN cord-006870-f5w6fw6q 5192 11 magnetic magnetic JJ cord-006870-f5w6fw6q 5192 12 resonance resonance NN cord-006870-f5w6fw6q 5192 13 vessel vessel NN cord-006870-f5w6fw6q 5192 14 wall wall NN cord-006870-f5w6fw6q 5192 15 imaging imaging NNP cord-006870-f5w6fw6q 5192 16 constitutes constitute VBZ cord-006870-f5w6fw6q 5192 17 a a DT cord-006870-f5w6fw6q 5192 18 promising promising JJ cord-006870-f5w6fw6q 5192 19 marker marker NN cord-006870-f5w6fw6q 5192 20 of of IN cord-006870-f5w6fw6q 5192 21 aneurysm aneurysm NN cord-006870-f5w6fw6q 5192 22 instability instability NN cord-006870-f5w6fw6q 5192 23 in in IN cord-006870-f5w6fw6q 5192 24 this this DT cord-006870-f5w6fw6q 5192 25 population population NN cord-006870-f5w6fw6q 5192 26 . . . cord-006870-f5w6fw6q 5193 1 To to TO cord-006870-f5w6fw6q 5193 2 find find VB cord-006870-f5w6fw6q 5193 3 risk risk NN cord-006870-f5w6fw6q 5193 4 factors factor NNS cord-006870-f5w6fw6q 5193 5 for for IN cord-006870-f5w6fw6q 5193 6 aneurysm aneurysm NN cord-006870-f5w6fw6q 5193 7 instability instability NN cord-006870-f5w6fw6q 5193 8 , , , cord-006870-f5w6fw6q 5193 9 we -PRON- PRP cord-006870-f5w6fw6q 5193 10 sought seek VBD cord-006870-f5w6fw6q 5193 11 to to TO cord-006870-f5w6fw6q 5193 12 identify identify VB cord-006870-f5w6fw6q 5193 13 predictors predictor NNS cord-006870-f5w6fw6q 5193 14 of of IN cord-006870-f5w6fw6q 5193 15 VWE VWE NNP cord-006870-f5w6fw6q 5193 16 in in IN cord-006870-f5w6fw6q 5193 17 patients patient NNS cord-006870-f5w6fw6q 5193 18 with with IN cord-006870-f5w6fw6q 5193 19 unruptured unruptured JJ cord-006870-f5w6fw6q 5193 20 ICAs ica NNS cord-006870-f5w6fw6q 5193 21 . . . cord-006870-f5w6fw6q 5194 1 We -PRON- PRP cord-006870-f5w6fw6q 5194 2 conducted conduct VBD cord-006870-f5w6fw6q 5194 3 a a DT cord-006870-f5w6fw6q 5194 4 retrospective retrospective JJ cord-006870-f5w6fw6q 5194 5 analysis analysis NN cord-006870-f5w6fw6q 5194 6 of of IN cord-006870-f5w6fw6q 5194 7 prospectively prospectively RB cord-006870-f5w6fw6q 5194 8 collected collect VBN cord-006870-f5w6fw6q 5194 9 data datum NNS cord-006870-f5w6fw6q 5194 10 on on IN cord-006870-f5w6fw6q 5194 11 patients patient NNS cord-006870-f5w6fw6q 5194 12 with with IN cord-006870-f5w6fw6q 5194 13 unruptured unruptured JJ cord-006870-f5w6fw6q 5194 14 ICA ICA NNP cord-006870-f5w6fw6q 5194 15 evaluated evaluate VBN cord-006870-f5w6fw6q 5194 16 by by IN cord-006870-f5w6fw6q 5194 17 a a DT cord-006870-f5w6fw6q 5194 18 single single JJ cord-006870-f5w6fw6q 5194 19 provider provider NN cord-006870-f5w6fw6q 5194 20 . . . cord-006870-f5w6fw6q 5195 1 All all DT cord-006870-f5w6fw6q 5195 2 patients patient NNS cord-006870-f5w6fw6q 5195 3 were be VBD cord-006870-f5w6fw6q 5195 4 evaluated evaluate VBN cord-006870-f5w6fw6q 5195 5 using use VBG cord-006870-f5w6fw6q 5195 6 a a DT cord-006870-f5w6fw6q 5195 7 previously previously RB cord-006870-f5w6fw6q 5195 8 validated validate VBN cord-006870-f5w6fw6q 5195 9 algorithm algorithm NN cord-006870-f5w6fw6q 5195 10 to to TO cord-006870-f5w6fw6q 5195 11 ascertain ascertain VB cord-006870-f5w6fw6q 5195 12 VWE VWE NNP cord-006870-f5w6fw6q 5195 13 using use VBG cord-006870-f5w6fw6q 5195 14 high high JJ cord-006870-f5w6fw6q 5195 15 - - HYPH cord-006870-f5w6fw6q 5195 16 resolution resolution NN cord-006870-f5w6fw6q 5195 17 magnetic magnetic JJ cord-006870-f5w6fw6q 5195 18 resonance resonance NN cord-006870-f5w6fw6q 5195 19 vessel vessel NN cord-006870-f5w6fw6q 5195 20 wall wall NN cord-006870-f5w6fw6q 5195 21 imaging imaging NNP cord-006870-f5w6fw6q 5195 22 . . . cord-006870-f5w6fw6q 5196 1 Two two CD cord-006870-f5w6fw6q 5196 2 different different JJ cord-006870-f5w6fw6q 5196 3 raters rater NNS cord-006870-f5w6fw6q 5196 4 , , , cord-006870-f5w6fw6q 5196 5 blinded blind VBN cord-006870-f5w6fw6q 5196 6 to to IN cord-006870-f5w6fw6q 5196 7 the the DT cord-006870-f5w6fw6q 5196 8 study study NN cord-006870-f5w6fw6q 5196 9 data datum NNS cord-006870-f5w6fw6q 5196 10 , , , cord-006870-f5w6fw6q 5196 11 categorized categorize VBD cord-006870-f5w6fw6q 5196 12 all all DT cord-006870-f5w6fw6q 5196 13 observed observe VBN cord-006870-f5w6fw6q 5196 14 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5196 15 as as IN cord-006870-f5w6fw6q 5196 16 VWE VWE NNP cord-006870-f5w6fw6q 5196 17 - - HYPH cord-006870-f5w6fw6q 5196 18 positive positive JJ cord-006870-f5w6fw6q 5196 19 or or CC cord-006870-f5w6fw6q 5196 20 VWE vwe NN cord-006870-f5w6fw6q 5196 21 - - HYPH cord-006870-f5w6fw6q 5196 22 negative negative JJ cord-006870-f5w6fw6q 5196 23 . . . cord-006870-f5w6fw6q 5197 1 Kappa Kappa NNP cord-006870-f5w6fw6q 5197 2 statistics statistic NNS cord-006870-f5w6fw6q 5197 3 were be VBD cord-006870-f5w6fw6q 5197 4 used use VBN cord-006870-f5w6fw6q 5197 5 to to TO cord-006870-f5w6fw6q 5197 6 evaluate evaluate VB cord-006870-f5w6fw6q 5197 7 the the DT cord-006870-f5w6fw6q 5197 8 reproducibility reproducibility NN cord-006870-f5w6fw6q 5197 9 of of IN cord-006870-f5w6fw6q 5197 10 this this DT cord-006870-f5w6fw6q 5197 11 approach approach NN cord-006870-f5w6fw6q 5197 12 . . . cord-006870-f5w6fw6q 5198 1 Univariable univariable JJ cord-006870-f5w6fw6q 5198 2 and and CC cord-006870-f5w6fw6q 5198 3 multivariate multivariate JJ cord-006870-f5w6fw6q 5198 4 logistic logistic JJ cord-006870-f5w6fw6q 5198 5 regression regression NN cord-006870-f5w6fw6q 5198 6 modelling modelling NN cord-006870-f5w6fw6q 5198 7 was be VBD cord-006870-f5w6fw6q 5198 8 utilized utilize VBN cord-006870-f5w6fw6q 5198 9 to to TO cord-006870-f5w6fw6q 5198 10 identify identify VB cord-006870-f5w6fw6q 5198 11 factors factor NNS cord-006870-f5w6fw6q 5198 12 associated associate VBN cord-006870-f5w6fw6q 5198 13 with with IN cord-006870-f5w6fw6q 5198 14 VWE VWE NNP cord-006870-f5w6fw6q 5198 15 after after IN cord-006870-f5w6fw6q 5198 16 adjusting adjust VBG cord-006870-f5w6fw6q 5198 17 for for IN cord-006870-f5w6fw6q 5198 18 potential potential JJ cord-006870-f5w6fw6q 5198 19 confounders confounder NNS cord-006870-f5w6fw6q 5198 20 . . . cord-006870-f5w6fw6q 5199 1 94 94 CD cord-006870-f5w6fw6q 5199 2 patients patient NNS cord-006870-f5w6fw6q 5199 3 with with IN cord-006870-f5w6fw6q 5199 4 unruptured unruptured JJ cord-006870-f5w6fw6q 5199 5 ICA ICA NNP cord-006870-f5w6fw6q 5199 6 were be VBD cord-006870-f5w6fw6q 5199 7 included include VBN cord-006870-f5w6fw6q 5199 8 in in IN cord-006870-f5w6fw6q 5199 9 the the DT cord-006870-f5w6fw6q 5199 10 analysis analysis NN cord-006870-f5w6fw6q 5199 11 ( ( -LRB- cord-006870-f5w6fw6q 5199 12 mean mean VB cord-006870-f5w6fw6q 5199 13 age age NN cord-006870-f5w6fw6q 5199 14 59 59 CD cord-006870-f5w6fw6q 5199 15 [ [ -LRB- cord-006870-f5w6fw6q 5199 16 SD SD NNP cord-006870-f5w6fw6q 5199 17 14 14 CD cord-006870-f5w6fw6q 5199 18 ] ] -RRB- cord-006870-f5w6fw6q 5199 19 , , , cord-006870-f5w6fw6q 5199 20 female female JJ cord-006870-f5w6fw6q 5199 21 sex sex NN cord-006870-f5w6fw6q 5199 22 77 77 CD cord-006870-f5w6fw6q 5199 23 [ [ -LRB- cord-006870-f5w6fw6q 5199 24 82 82 CD cord-006870-f5w6fw6q 5199 25 % % NN cord-006870-f5w6fw6q 5199 26 ] ] -RRB- cord-006870-f5w6fw6q 5199 27 ) ) -RRB- cord-006870-f5w6fw6q 5199 28 . . . cord-006870-f5w6fw6q 5200 1 Of of IN cord-006870-f5w6fw6q 5200 2 these these DT cord-006870-f5w6fw6q 5200 3 , , , cord-006870-f5w6fw6q 5200 4 34 34 CD cord-006870-f5w6fw6q 5200 5 ( ( -LRB- cord-006870-f5w6fw6q 5200 6 36 36 CD cord-006870-f5w6fw6q 5200 7 % % NN cord-006870-f5w6fw6q 5200 8 ) ) -RRB- cord-006870-f5w6fw6q 5200 9 were be VBD cord-006870-f5w6fw6q 5200 10 VWE VWE NNP cord-006870-f5w6fw6q 5200 11 - - HYPH cord-006870-f5w6fw6q 5200 12 positive positive JJ cord-006870-f5w6fw6q 5200 13 and and CC cord-006870-f5w6fw6q 5200 14 60 60 CD cord-006870-f5w6fw6q 5200 15 ( ( -LRB- cord-006870-f5w6fw6q 5200 16 64 64 CD cord-006870-f5w6fw6q 5200 17 % % NN cord-006870-f5w6fw6q 5200 18 ) ) -RRB- cord-006870-f5w6fw6q 5200 19 were be VBD cord-006870-f5w6fw6q 5200 20 VWE vwe NN cord-006870-f5w6fw6q 5200 21 - - HYPH cord-006870-f5w6fw6q 5200 22 negative negative JJ cord-006870-f5w6fw6q 5200 23 . . . cord-006870-f5w6fw6q 5201 1 Inter inter JJ cord-006870-f5w6fw6q 5201 2 - - JJ cord-006870-f5w6fw6q 5201 3 rater rater JJ cord-006870-f5w6fw6q 5201 4 reliability reliability NN cord-006870-f5w6fw6q 5201 5 for for IN cord-006870-f5w6fw6q 5201 6 VWE VWE NNP cord-006870-f5w6fw6q 5201 7 ascertainment ascertainment NN cord-006870-f5w6fw6q 5201 8 was be VBD cord-006870-f5w6fw6q 5201 9 excellent excellent JJ cord-006870-f5w6fw6q 5201 10 ( ( -LRB- cord-006870-f5w6fw6q 5201 11 kappa kappa NNP cord-006870-f5w6fw6q 5201 12 0.86 0.86 CD cord-006870-f5w6fw6q 5201 13 , , , cord-006870-f5w6fw6q 5201 14 95%CI 95%ci CD cord-006870-f5w6fw6q 5201 15 0.75 0.75 CD cord-006870-f5w6fw6q 5201 16 , , , cord-006870-f5w6fw6q 5201 17 0.97 0.97 CD cord-006870-f5w6fw6q 5201 18 ) ) -RRB- cord-006870-f5w6fw6q 5201 19 . . . cord-006870-f5w6fw6q 5202 1 9 9 CD cord-006870-f5w6fw6q 5202 2 out out IN cord-006870-f5w6fw6q 5202 3 of of IN cord-006870-f5w6fw6q 5202 4 10 10 CD cord-006870-f5w6fw6q 5202 5 ( ( -LRB- cord-006870-f5w6fw6q 5202 6 90 90 CD cord-006870-f5w6fw6q 5202 7 % % NN cord-006870-f5w6fw6q 5202 8 ) ) -RRB- cord-006870-f5w6fw6q 5202 9 patients patient NNS cord-006870-f5w6fw6q 5202 10 presenting present VBG cord-006870-f5w6fw6q 5202 11 with with IN cord-006870-f5w6fw6q 5202 12 cranial cranial JJ cord-006870-f5w6fw6q 5202 13 nerve nerve NN cord-006870-f5w6fw6q 5202 14 palsy palsy NN cord-006870-f5w6fw6q 5202 15 were be VBD cord-006870-f5w6fw6q 5202 16 VWE vwe NN cord-006870-f5w6fw6q 5202 17 - - HYPH cord-006870-f5w6fw6q 5202 18 positive positive JJ cord-006870-f5w6fw6q 5202 19 . . . cord-006870-f5w6fw6q 5203 1 In in IN cord-006870-f5w6fw6q 5203 2 univariable univariable JJ cord-006870-f5w6fw6q 5203 3 analysis analysis NN cord-006870-f5w6fw6q 5203 4 , , , cord-006870-f5w6fw6q 5203 5 age age NN cord-006870-f5w6fw6q 5203 6 ( ( -LRB- cord-006870-f5w6fw6q 5203 7 p=0.03 p=0.03 NN cord-006870-f5w6fw6q 5203 8 ) ) -RRB- cord-006870-f5w6fw6q 5203 9 , , , cord-006870-f5w6fw6q 5203 10 headache headache NN cord-006870-f5w6fw6q 5203 11 on on IN cord-006870-f5w6fw6q 5203 12 presentation presentation NN cord-006870-f5w6fw6q 5203 13 ( ( -LRB- cord-006870-f5w6fw6q 5203 14 p=0.004 p=0.004 NNP cord-006870-f5w6fw6q 5203 15 ) ) -RRB- cord-006870-f5w6fw6q 5203 16 , , , cord-006870-f5w6fw6q 5203 17 and and CC cord-006870-f5w6fw6q 5203 18 size size NN cord-006870-f5w6fw6q 5203 19 ( ( -LRB- cord-006870-f5w6fw6q 5203 20 p<0.001 p<0.001 NNS cord-006870-f5w6fw6q 5203 21 , , , cord-006870-f5w6fw6q 5203 22 per per IN cord-006870-f5w6fw6q 5203 23 additional additional JJ cord-006870-f5w6fw6q 5203 24 millimeter millimeter NN cord-006870-f5w6fw6q 5203 25 ) ) -RRB- cord-006870-f5w6fw6q 5203 26 were be VBD cord-006870-f5w6fw6q 5203 27 associated associate VBN cord-006870-f5w6fw6q 5203 28 with with IN cord-006870-f5w6fw6q 5203 29 VWE vwe NN cord-006870-f5w6fw6q 5203 30 - - HYPH cord-006870-f5w6fw6q 5203 31 positive positive JJ cord-006870-f5w6fw6q 5203 32 status status NN cord-006870-f5w6fw6q 5203 33 . . . cord-006870-f5w6fw6q 5204 1 In in IN cord-006870-f5w6fw6q 5204 2 multivariable multivariable JJ cord-006870-f5w6fw6q 5204 3 analysis analysis NN cord-006870-f5w6fw6q 5204 4 , , , cord-006870-f5w6fw6q 5204 5 headache headache NN cord-006870-f5w6fw6q 5204 6 on on IN cord-006870-f5w6fw6q 5204 7 presentation presentation NN cord-006870-f5w6fw6q 5204 8 ( ( -LRB- cord-006870-f5w6fw6q 5204 9 p=0.007 p=0.007 NNP cord-006870-f5w6fw6q 5204 10 ) ) -RRB- cord-006870-f5w6fw6q 5204 11 and and CC cord-006870-f5w6fw6q 5204 12 size size NN cord-006870-f5w6fw6q 5204 13 ( ( -LRB- cord-006870-f5w6fw6q 5204 14 p=0.003 p=0.003 NNP cord-006870-f5w6fw6q 5204 15 ) ) -RRB- cord-006870-f5w6fw6q 5204 16 remained remain VBD cord-006870-f5w6fw6q 5204 17 independently independently RB cord-006870-f5w6fw6q 5204 18 associated associate VBN cord-006870-f5w6fw6q 5204 19 with with IN cord-006870-f5w6fw6q 5204 20 VWE VWE NNP cord-006870-f5w6fw6q 5204 21 . . . cord-006870-f5w6fw6q 5205 1 Cranial cranial JJ cord-006870-f5w6fw6q 5205 2 nerve nerve NN cord-006870-f5w6fw6q 5205 3 palsy palsy NN cord-006870-f5w6fw6q 5205 4 is be VBZ cord-006870-f5w6fw6q 5205 5 an an DT cord-006870-f5w6fw6q 5205 6 established establish VBN cord-006870-f5w6fw6q 5205 7 clinical clinical JJ cord-006870-f5w6fw6q 5205 8 marker marker NN cord-006870-f5w6fw6q 5205 9 of of IN cord-006870-f5w6fw6q 5205 10 aneurysm aneurysm NN cord-006870-f5w6fw6q 5205 11 instability instability NN cord-006870-f5w6fw6q 5205 12 ; ; : cord-006870-f5w6fw6q 5205 13 consequently consequently RB cord-006870-f5w6fw6q 5205 14 , , , cord-006870-f5w6fw6q 5205 15 our -PRON- PRP$ cord-006870-f5w6fw6q 5205 16 results result NNS cord-006870-f5w6fw6q 5205 17 confirm confirm VBP cord-006870-f5w6fw6q 5205 18 the the DT cord-006870-f5w6fw6q 5205 19 role role NN cord-006870-f5w6fw6q 5205 20 of of IN cord-006870-f5w6fw6q 5205 21 VWE VWE NNP cord-006870-f5w6fw6q 5205 22 as as IN cord-006870-f5w6fw6q 5205 23 a a DT cord-006870-f5w6fw6q 5205 24 marker marker NN cord-006870-f5w6fw6q 5205 25 of of IN cord-006870-f5w6fw6q 5205 26 aneurysm aneurysm NN cord-006870-f5w6fw6q 5205 27 instability instability NN cord-006870-f5w6fw6q 5205 28 . . . cord-006870-f5w6fw6q 5206 1 Headache headache NN cord-006870-f5w6fw6q 5206 2 on on IN cord-006870-f5w6fw6q 5206 3 presentation presentation NN cord-006870-f5w6fw6q 5206 4 and and CC cord-006870-f5w6fw6q 5206 5 aneurysm aneurysm NN cord-006870-f5w6fw6q 5206 6 size size NN cord-006870-f5w6fw6q 5206 7 are be VBP cord-006870-f5w6fw6q 5206 8 independently independently RB cord-006870-f5w6fw6q 5206 9 associated associate VBN cord-006870-f5w6fw6q 5206 10 with with IN cord-006870-f5w6fw6q 5206 11 VWE VWE NNP cord-006870-f5w6fw6q 5206 12 ; ; : cord-006870-f5w6fw6q 5206 13 these these DT cord-006870-f5w6fw6q 5206 14 risk risk NN cord-006870-f5w6fw6q 5206 15 factors factor NNS cord-006870-f5w6fw6q 5206 16 for for IN cord-006870-f5w6fw6q 5206 17 aneurysm aneurysm NN cord-006870-f5w6fw6q 5206 18 instability instability NN cord-006870-f5w6fw6q 5206 19 could could MD cord-006870-f5w6fw6q 5206 20 be be VB cord-006870-f5w6fw6q 5206 21 used use VBN cord-006870-f5w6fw6q 5206 22 to to TO cord-006870-f5w6fw6q 5206 23 select select VB cord-006870-f5w6fw6q 5206 24 patients patient NNS cord-006870-f5w6fw6q 5206 25 with with IN cord-006870-f5w6fw6q 5206 26 unruptured unruptured JJ cord-006870-f5w6fw6q 5206 27 ICAs ica NNS cord-006870-f5w6fw6q 5206 28 that that WDT cord-006870-f5w6fw6q 5206 29 may may MD cord-006870-f5w6fw6q 5206 30 benefit benefit VB cord-006870-f5w6fw6q 5206 31 from from IN cord-006870-f5w6fw6q 5206 32 vessel vessel NN cord-006870-f5w6fw6q 5206 33 wall wall NN cord-006870-f5w6fw6q 5206 34 imaging imaging NNP cord-006870-f5w6fw6q 5206 35 . . . cord-006870-f5w6fw6q 5207 1 Prognostication prognostication NN cord-006870-f5w6fw6q 5207 2 in in IN cord-006870-f5w6fw6q 5207 3 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5207 4 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5208 1 ( ( -LRB- cord-006870-f5w6fw6q 5208 2 SAH SAH NNP cord-006870-f5w6fw6q 5208 3 ) ) -RRB- cord-006870-f5w6fw6q 5208 4 patients patient NNS cord-006870-f5w6fw6q 5208 5 presenting present VBG cord-006870-f5w6fw6q 5208 6 in in IN cord-006870-f5w6fw6q 5208 7 coma coma NN cord-006870-f5w6fw6q 5208 8 is be VBZ cord-006870-f5w6fw6q 5208 9 crucial crucial JJ cord-006870-f5w6fw6q 5208 10 for for IN cord-006870-f5w6fw6q 5208 11 surgical surgical JJ cord-006870-f5w6fw6q 5208 12 decision decision NN cord-006870-f5w6fw6q 5208 13 making making NN cord-006870-f5w6fw6q 5208 14 . . . cord-006870-f5w6fw6q 5209 1 Indications indication NNS cord-006870-f5w6fw6q 5209 2 for for IN cord-006870-f5w6fw6q 5209 3 aggressive aggressive JJ cord-006870-f5w6fw6q 5209 4 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 5209 5 treatment treatment NN cord-006870-f5w6fw6q 5209 6 are be VBP cord-006870-f5w6fw6q 5209 7 unlikely unlikely JJ cord-006870-f5w6fw6q 5209 8 for for IN cord-006870-f5w6fw6q 5209 9 those those DT cord-006870-f5w6fw6q 5209 10 not not RB cord-006870-f5w6fw6q 5209 11 demonstrating demonstrate VBG cord-006870-f5w6fw6q 5209 12 signs sign NNS cord-006870-f5w6fw6q 5209 13 of of IN cord-006870-f5w6fw6q 5209 14 neurological neurological JJ cord-006870-f5w6fw6q 5209 15 improvement improvement NN cord-006870-f5w6fw6q 5209 16 chronologically chronologically RB cord-006870-f5w6fw6q 5209 17 or or CC cord-006870-f5w6fw6q 5209 18 after after IN cord-006870-f5w6fw6q 5209 19 ventricular ventricular JJ cord-006870-f5w6fw6q 5209 20 drainage drainage NN cord-006870-f5w6fw6q 5209 21 . . . cord-006870-f5w6fw6q 5210 1 Early early JJ cord-006870-f5w6fw6q 5210 2 neurological neurological JJ cord-006870-f5w6fw6q 5210 3 evaluation evaluation NN cord-006870-f5w6fw6q 5210 4 is be VBZ cord-006870-f5w6fw6q 5210 5 , , , cord-006870-f5w6fw6q 5210 6 however however RB cord-006870-f5w6fw6q 5210 7 , , , cord-006870-f5w6fw6q 5210 8 challenging challenge VBG cord-006870-f5w6fw6q 5210 9 in in IN cord-006870-f5w6fw6q 5210 10 critically critically RB cord-006870-f5w6fw6q 5210 11 ill ill JJ cord-006870-f5w6fw6q 5210 12 SAH SAH NNP cord-006870-f5w6fw6q 5210 13 patients patient NNS cord-006870-f5w6fw6q 5210 14 requiring require VBG cord-006870-f5w6fw6q 5210 15 anesthesia anesthesia NN cord-006870-f5w6fw6q 5210 16 and and CC cord-006870-f5w6fw6q 5210 17 intubation intubation NN cord-006870-f5w6fw6q 5210 18 for for IN cord-006870-f5w6fw6q 5210 19 airway airway NN cord-006870-f5w6fw6q 5210 20 protection protection NN cord-006870-f5w6fw6q 5210 21 . . . cord-006870-f5w6fw6q 5211 1 In in IN cord-006870-f5w6fw6q 5211 2 this this DT cord-006870-f5w6fw6q 5211 3 single single JJ cord-006870-f5w6fw6q 5211 4 - - HYPH cord-006870-f5w6fw6q 5211 5 center center NN cord-006870-f5w6fw6q 5211 6 retrospective retrospective JJ cord-006870-f5w6fw6q 5211 7 study study NN cord-006870-f5w6fw6q 5211 8 , , , cord-006870-f5w6fw6q 5211 9 we -PRON- PRP cord-006870-f5w6fw6q 5211 10 applied apply VBD cord-006870-f5w6fw6q 5211 11 continuous continuous JJ cord-006870-f5w6fw6q 5211 12 amplitude amplitude NN cord-006870-f5w6fw6q 5211 13 - - HYPH cord-006870-f5w6fw6q 5211 14 integrated integrate VBN cord-006870-f5w6fw6q 5211 15 EEG EEG NNP cord-006870-f5w6fw6q 5211 16 ( ( -LRB- cord-006870-f5w6fw6q 5211 17 aEEG aeeg NN cord-006870-f5w6fw6q 5211 18 ) ) -RRB- cord-006870-f5w6fw6q 5211 19 monitoring monitoring NN cord-006870-f5w6fw6q 5211 20 using use VBG cord-006870-f5w6fw6q 5211 21 a a DT cord-006870-f5w6fw6q 5211 22 subhairline subhairline JJ cord-006870-f5w6fw6q 5211 23 montage montage NN cord-006870-f5w6fw6q 5211 24 for for IN cord-006870-f5w6fw6q 5211 25 WFNS WFNS NNP cord-006870-f5w6fw6q 5211 26 Grade Grade NNP cord-006870-f5w6fw6q 5211 27 V V NNP cord-006870-f5w6fw6q 5211 28 patients patient NNS cord-006870-f5w6fw6q 5211 29 who who WP cord-006870-f5w6fw6q 5211 30 did do VBD cord-006870-f5w6fw6q 5211 31 not not RB cord-006870-f5w6fw6q 5211 32 undergo undergo VB cord-006870-f5w6fw6q 5211 33 emergency emergency NN cord-006870-f5w6fw6q 5211 34 aneurysm aneurysm NN cord-006870-f5w6fw6q 5211 35 treatment treatment NN cord-006870-f5w6fw6q 5211 36 . . . cord-006870-f5w6fw6q 5212 1 Monitoring monitoring NN cord-006870-f5w6fw6q 5212 2 was be VBD cord-006870-f5w6fw6q 5212 3 initiated initiate VBN cord-006870-f5w6fw6q 5212 4 soon soon RB cord-006870-f5w6fw6q 5212 5 after after IN cord-006870-f5w6fw6q 5212 6 admission admission NN cord-006870-f5w6fw6q 5212 7 to to IN cord-006870-f5w6fw6q 5212 8 the the DT cord-006870-f5w6fw6q 5212 9 ICU ICU NNP cord-006870-f5w6fw6q 5212 10 . . . cord-006870-f5w6fw6q 5213 1 Patterns pattern NNS cord-006870-f5w6fw6q 5213 2 of of IN cord-006870-f5w6fw6q 5213 3 aEEG aeeg JJ cord-006870-f5w6fw6q 5213 4 findings finding NNS cord-006870-f5w6fw6q 5213 5 were be VBD cord-006870-f5w6fw6q 5213 6 classified classify VBN cord-006870-f5w6fw6q 5213 7 according accord VBG cord-006870-f5w6fw6q 5213 8 to to IN cord-006870-f5w6fw6q 5213 9 Rundgren Rundgren NNP cord-006870-f5w6fw6q 5213 10 , , , cord-006870-f5w6fw6q 5213 11 et et NNP cord-006870-f5w6fw6q 5213 12 al al NNP cord-006870-f5w6fw6q 5213 13 . . . cord-006870-f5w6fw6q 5214 1 as as IN cord-006870-f5w6fw6q 5214 2 follows follow VBZ cord-006870-f5w6fw6q 5214 3 : : : cord-006870-f5w6fw6q 5214 4 flat flat JJ cord-006870-f5w6fw6q 5214 5 ( ( -LRB- cord-006870-f5w6fw6q 5214 6 F F NNP cord-006870-f5w6fw6q 5214 7 ) ) -RRB- cord-006870-f5w6fw6q 5214 8 ; ; : cord-006870-f5w6fw6q 5214 9 suppression suppression NN cord-006870-f5w6fw6q 5214 10 - - HYPH cord-006870-f5w6fw6q 5214 11 burst burst NN cord-006870-f5w6fw6q 5214 12 ( ( -LRB- cord-006870-f5w6fw6q 5214 13 SB SB NNP cord-006870-f5w6fw6q 5214 14 ) ) -RRB- cord-006870-f5w6fw6q 5214 15 ; ; : cord-006870-f5w6fw6q 5214 16 electrographic electrographic JJ cord-006870-f5w6fw6q 5214 17 status status NN cord-006870-f5w6fw6q 5214 18 epilepticus epilepticus NN cord-006870-f5w6fw6q 5214 19 ( ( -LRB- cord-006870-f5w6fw6q 5214 20 ESE ESE NNP cord-006870-f5w6fw6q 5214 21 ) ) -RRB- cord-006870-f5w6fw6q 5214 22 ; ; : cord-006870-f5w6fw6q 5214 23 and and CC cord-006870-f5w6fw6q 5214 24 continuous continuous JJ cord-006870-f5w6fw6q 5214 25 ( ( -LRB- cord-006870-f5w6fw6q 5214 26 C c NN cord-006870-f5w6fw6q 5214 27 ) ) -RRB- cord-006870-f5w6fw6q 5214 28 . . . cord-006870-f5w6fw6q 5215 1 Based base VBN cord-006870-f5w6fw6q 5215 2 on on IN cord-006870-f5w6fw6q 5215 3 the the DT cord-006870-f5w6fw6q 5215 4 aEEG aeeg JJ cord-006870-f5w6fw6q 5215 5 findings finding NNS cord-006870-f5w6fw6q 5215 6 , , , cord-006870-f5w6fw6q 5215 7 indications indication NNS cord-006870-f5w6fw6q 5215 8 for for IN cord-006870-f5w6fw6q 5215 9 aneurysm aneurysm NN cord-006870-f5w6fw6q 5215 10 treatment treatment NN cord-006870-f5w6fw6q 5215 11 were be VBD cord-006870-f5w6fw6q 5215 12 reevaluated reevaluate VBN cord-006870-f5w6fw6q 5215 13 . . . cord-006870-f5w6fw6q 5216 1 Outcome outcome NN cord-006870-f5w6fw6q 5216 2 was be VBD cord-006870-f5w6fw6q 5216 3 assessed assess VBN cord-006870-f5w6fw6q 5216 4 at at IN cord-006870-f5w6fw6q 5216 5 six six CD cord-006870-f5w6fw6q 5216 6 months month NNS cord-006870-f5w6fw6q 5216 7 using use VBG cord-006870-f5w6fw6q 5216 8 the the DT cord-006870-f5w6fw6q 5216 9 Glasgow Glasgow NNP cord-006870-f5w6fw6q 5216 10 Outcome Outcome NNP cord-006870-f5w6fw6q 5216 11 Scale Scale NNP cord-006870-f5w6fw6q 5216 12 . . . cord-006870-f5w6fw6q 5217 1 Twenty twenty CD cord-006870-f5w6fw6q 5217 2 - - HYPH cord-006870-f5w6fw6q 5217 3 three three CD cord-006870-f5w6fw6q 5217 4 patients patient NNS cord-006870-f5w6fw6q 5217 5 , , , cord-006870-f5w6fw6q 5217 6 8 8 CD cord-006870-f5w6fw6q 5217 7 men man NNS cord-006870-f5w6fw6q 5217 8 and and CC cord-006870-f5w6fw6q 5217 9 15 15 CD cord-006870-f5w6fw6q 5217 10 women woman NNS cord-006870-f5w6fw6q 5217 11 , , , cord-006870-f5w6fw6q 5217 12 aged aged JJ cord-006870-f5w6fw6q 5217 13 68.3 68.3 CD cord-006870-f5w6fw6q 5217 14 ± ± CD cord-006870-f5w6fw6q 5217 15 14.1 14.1 CD cord-006870-f5w6fw6q 5217 16 years year NNS cord-006870-f5w6fw6q 5217 17 ( ( -LRB- cord-006870-f5w6fw6q 5217 18 mean mean VB cord-006870-f5w6fw6q 5217 19 ± ± NNP cord-006870-f5w6fw6q 5217 20 SD SD NNP cord-006870-f5w6fw6q 5217 21 ) ) -RRB- cord-006870-f5w6fw6q 5217 22 , , , cord-006870-f5w6fw6q 5217 23 were be VBD cord-006870-f5w6fw6q 5217 24 eligible eligible JJ cord-006870-f5w6fw6q 5217 25 since since IN cord-006870-f5w6fw6q 5217 26 December December NNP cord-006870-f5w6fw6q 5217 27 2012 2012 CD cord-006870-f5w6fw6q 5217 28 . . . cord-006870-f5w6fw6q 5218 1 All all DT cord-006870-f5w6fw6q 5218 2 patients patient NNS cord-006870-f5w6fw6q 5218 3 underwent undergo VBD cord-006870-f5w6fw6q 5218 4 prophylactic prophylactic JJ cord-006870-f5w6fw6q 5218 5 intravenous intravenous JJ cord-006870-f5w6fw6q 5218 6 sedation sedation NN cord-006870-f5w6fw6q 5218 7 . . . cord-006870-f5w6fw6q 5219 1 The the DT cord-006870-f5w6fw6q 5219 2 population population NN cord-006870-f5w6fw6q 5219 3 represented represent VBD cord-006870-f5w6fw6q 5219 4 28 28 CD cord-006870-f5w6fw6q 5219 5 % % NN cord-006870-f5w6fw6q 5219 6 of of IN cord-006870-f5w6fw6q 5219 7 all all DT cord-006870-f5w6fw6q 5219 8 Grade grade NN cord-006870-f5w6fw6q 5219 9 V v NN cord-006870-f5w6fw6q 5219 10 patients patient NNS cord-006870-f5w6fw6q 5219 11 including include VBG cord-006870-f5w6fw6q 5219 12 those those DT cord-006870-f5w6fw6q 5219 13 resuscitated resuscitate VBN cord-006870-f5w6fw6q 5219 14 after after IN cord-006870-f5w6fw6q 5219 15 cardiac cardiac NNP cord-006870-f5w6fw6q 5219 16 ( ( -LRB- cord-006870-f5w6fw6q 5219 17 n=9 n=9 JJ cord-006870-f5w6fw6q 5219 18 ) ) -RRB- cord-006870-f5w6fw6q 5219 19 or or CC cord-006870-f5w6fw6q 5219 20 respiratory respiratory JJ cord-006870-f5w6fw6q 5219 21 ( ( -LRB- cord-006870-f5w6fw6q 5219 22 n=2 n=2 NNS cord-006870-f5w6fw6q 5219 23 ) ) -RRB- cord-006870-f5w6fw6q 5219 24 arrest arrest NN cord-006870-f5w6fw6q 5219 25 . . . cord-006870-f5w6fw6q 5220 1 The the DT cord-006870-f5w6fw6q 5220 2 Glasgow Glasgow NNP cord-006870-f5w6fw6q 5220 3 Coma Coma NNP cord-006870-f5w6fw6q 5220 4 Scale Scale NNP cord-006870-f5w6fw6q 5220 5 scores score NNS cord-006870-f5w6fw6q 5220 6 were be VBD cord-006870-f5w6fw6q 5220 7 3 3 CD cord-006870-f5w6fw6q 5221 1 ( ( -LRB- cord-006870-f5w6fw6q 5221 2 n= n= NNP cord-006870-f5w6fw6q 5221 3 21 21 CD cord-006870-f5w6fw6q 5221 4 ) ) -RRB- cord-006870-f5w6fw6q 5221 5 , , , cord-006870-f5w6fw6q 5221 6 4 4 LS cord-006870-f5w6fw6q 5221 7 ( ( -LRB- cord-006870-f5w6fw6q 5221 8 n=1 n=1 NNP cord-006870-f5w6fw6q 5221 9 ) ) -RRB- cord-006870-f5w6fw6q 5221 10 , , , cord-006870-f5w6fw6q 5221 11 and and CC cord-006870-f5w6fw6q 5221 12 5 5 LS cord-006870-f5w6fw6q 5221 13 ( ( -LRB- cord-006870-f5w6fw6q 5221 14 n=1 n=1 NNS cord-006870-f5w6fw6q 5221 15 ) ) -RRB- cord-006870-f5w6fw6q 5221 16 , , , cord-006870-f5w6fw6q 5221 17 respectively respectively RB cord-006870-f5w6fw6q 5221 18 . . . cord-006870-f5w6fw6q 5222 1 Aneurysms aneurysm NNS cord-006870-f5w6fw6q 5222 2 were be VBD cord-006870-f5w6fw6q 5222 3 located locate VBN cord-006870-f5w6fw6q 5222 4 in in IN cord-006870-f5w6fw6q 5222 5 the the DT cord-006870-f5w6fw6q 5222 6 posterior posterior JJ cord-006870-f5w6fw6q 5222 7 fossa fossa NN cord-006870-f5w6fw6q 5222 8 in in IN cord-006870-f5w6fw6q 5222 9 9 9 CD cord-006870-f5w6fw6q 5222 10 patients patient NNS cord-006870-f5w6fw6q 5222 11 ( ( -LRB- cord-006870-f5w6fw6q 5222 12 39 39 CD cord-006870-f5w6fw6q 5222 13 % % NN cord-006870-f5w6fw6q 5222 14 ) ) -RRB- cord-006870-f5w6fw6q 5222 15 . . . cord-006870-f5w6fw6q 5223 1 aEEG aeeg JJ cord-006870-f5w6fw6q 5223 2 monitoring monitoring NN cord-006870-f5w6fw6q 5223 3 was be VBD cord-006870-f5w6fw6q 5223 4 initiated initiate VBN cord-006870-f5w6fw6q 5223 5 11.8 11.8 CD cord-006870-f5w6fw6q 5223 6 ± ± CD cord-006870-f5w6fw6q 5223 7 12.2 12.2 CD cord-006870-f5w6fw6q 5223 8 hours hour NNS cord-006870-f5w6fw6q 5223 9 median median JJ cord-006870-f5w6fw6q 5223 10 8.4 8.4 CD cord-006870-f5w6fw6q 5223 11 , , , cord-006870-f5w6fw6q 5223 12 1.03 1.03 CD cord-006870-f5w6fw6q 5223 13 - - SYM cord-006870-f5w6fw6q 5223 14 41.7 41.7 CD cord-006870-f5w6fw6q 5223 15 hours hour NNS cord-006870-f5w6fw6q 5223 16 after after IN cord-006870-f5w6fw6q 5223 17 arrival arrival NN cord-006870-f5w6fw6q 5223 18 . . . cord-006870-f5w6fw6q 5224 1 All all DT cord-006870-f5w6fw6q 5224 2 patients patient NNS cord-006870-f5w6fw6q 5224 3 showing show VBG cord-006870-f5w6fw6q 5224 4 early early JJ cord-006870-f5w6fw6q 5224 5 F F NNP cord-006870-f5w6fw6q 5224 6 ( ( -LRB- cord-006870-f5w6fw6q 5224 7 n=12 n=12 NNP cord-006870-f5w6fw6q 5224 8 ) ) -RRB- cord-006870-f5w6fw6q 5224 9 or or CC cord-006870-f5w6fw6q 5224 10 SB SB NNP cord-006870-f5w6fw6q 5224 11 patterns pattern NNS cord-006870-f5w6fw6q 5224 12 ( ( -LRB- cord-006870-f5w6fw6q 5224 13 n=3 n=3 NN cord-006870-f5w6fw6q 5224 14 ) ) -RRB- cord-006870-f5w6fw6q 5224 15 died die VBD cord-006870-f5w6fw6q 5224 16 . . . cord-006870-f5w6fw6q 5225 1 One one CD cord-006870-f5w6fw6q 5225 2 patient patient NN cord-006870-f5w6fw6q 5225 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5225 4 ESE ESE NNP cord-006870-f5w6fw6q 5225 5 remained remain VBD cord-006870-f5w6fw6q 5225 6 in in IN cord-006870-f5w6fw6q 5225 7 a a DT cord-006870-f5w6fw6q 5225 8 persistent persistent JJ cord-006870-f5w6fw6q 5225 9 vegetative vegetative JJ cord-006870-f5w6fw6q 5225 10 state state NN cord-006870-f5w6fw6q 5225 11 . . . cord-006870-f5w6fw6q 5226 1 Five five CD cord-006870-f5w6fw6q 5226 2 out out IN cord-006870-f5w6fw6q 5226 3 of of IN cord-006870-f5w6fw6q 5226 4 7 7 CD cord-006870-f5w6fw6q 5226 5 patients patient NNS cord-006870-f5w6fw6q 5226 6 with with IN cord-006870-f5w6fw6q 5226 7 a a DT cord-006870-f5w6fw6q 5226 8 C c NN cord-006870-f5w6fw6q 5226 9 pattern pattern NN cord-006870-f5w6fw6q 5226 10 underwent undergo VBD cord-006870-f5w6fw6q 5226 11 aneurysm aneurysm NN cord-006870-f5w6fw6q 5226 12 treatment treatment NN cord-006870-f5w6fw6q 5226 13 ; ; : cord-006870-f5w6fw6q 5226 14 4 4 CD cord-006870-f5w6fw6q 5226 15 clippings clipping NNS cord-006870-f5w6fw6q 5226 16 and and CC cord-006870-f5w6fw6q 5226 17 1 1 CD cord-006870-f5w6fw6q 5226 18 coil coil NN cord-006870-f5w6fw6q 5226 19 embolization embolization NN cord-006870-f5w6fw6q 5226 20 . . . cord-006870-f5w6fw6q 5227 1 Moderate moderate JJ cord-006870-f5w6fw6q 5227 2 disability disability NN cord-006870-f5w6fw6q 5227 3 was be VBD cord-006870-f5w6fw6q 5227 4 attained attain VBN cord-006870-f5w6fw6q 5227 5 in in IN cord-006870-f5w6fw6q 5227 6 3 3 CD cord-006870-f5w6fw6q 5227 7 and and CC cord-006870-f5w6fw6q 5227 8 severe severe JJ cord-006870-f5w6fw6q 5227 9 disability disability NN cord-006870-f5w6fw6q 5227 10 in in IN cord-006870-f5w6fw6q 5227 11 2 2 CD cord-006870-f5w6fw6q 5227 12 . . . cord-006870-f5w6fw6q 5228 1 Two two CD cord-006870-f5w6fw6q 5228 2 patients patient NNS cord-006870-f5w6fw6q 5228 3 undergoing undergo VBG cord-006870-f5w6fw6q 5228 4 conservative conservative JJ cord-006870-f5w6fw6q 5228 5 therapy therapy NN cord-006870-f5w6fw6q 5228 6 died die VBD cord-006870-f5w6fw6q 5228 7 . . . cord-006870-f5w6fw6q 5229 1 Continuous continuous JJ cord-006870-f5w6fw6q 5229 2 aEEG aeeg NN cord-006870-f5w6fw6q 5229 3 provided provide VBD cord-006870-f5w6fw6q 5229 4 useful useful JJ cord-006870-f5w6fw6q 5229 5 prognostic prognostic JJ cord-006870-f5w6fw6q 5229 6 information information NN cord-006870-f5w6fw6q 5229 7 for for IN cord-006870-f5w6fw6q 5229 8 identifying identify VBG cord-006870-f5w6fw6q 5229 9 salvageable salvageable JJ cord-006870-f5w6fw6q 5229 10 SAH SAH NNP cord-006870-f5w6fw6q 5229 11 patients patient NNS cord-006870-f5w6fw6q 5229 12 undergoing undergo VBG cord-006870-f5w6fw6q 5229 13 sedation sedation NN cord-006870-f5w6fw6q 5229 14 in in IN cord-006870-f5w6fw6q 5229 15 the the DT cord-006870-f5w6fw6q 5229 16 early early JJ cord-006870-f5w6fw6q 5229 17 phase phase NN cord-006870-f5w6fw6q 5229 18 . . . cord-006870-f5w6fw6q 5230 1 Delayed delayed JJ cord-006870-f5w6fw6q 5230 2 cerebral cerebral JJ cord-006870-f5w6fw6q 5230 3 ischemia ischemia NN cord-006870-f5w6fw6q 5230 4 ( ( -LRB- cord-006870-f5w6fw6q 5230 5 DCI DCI NNP cord-006870-f5w6fw6q 5230 6 ) ) -RRB- cord-006870-f5w6fw6q 5230 7 may may MD cord-006870-f5w6fw6q 5230 8 result result VB cord-006870-f5w6fw6q 5230 9 in in IN cord-006870-f5w6fw6q 5230 10 focal focal JJ cord-006870-f5w6fw6q 5230 11 neurological neurological JJ cord-006870-f5w6fw6q 5230 12 deficits deficit NNS cord-006870-f5w6fw6q 5230 13 and and CC cord-006870-f5w6fw6q 5230 14 cerebral cerebral JJ cord-006870-f5w6fw6q 5230 15 infarction infarction NN cord-006870-f5w6fw6q 5230 16 after after IN cord-006870-f5w6fw6q 5230 17 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5230 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5230 19 . . . cord-006870-f5w6fw6q 5231 1 While while IN cord-006870-f5w6fw6q 5231 2 global global JJ cord-006870-f5w6fw6q 5231 3 cerebral cerebral JJ cord-006870-f5w6fw6q 5231 4 blood blood NN cord-006870-f5w6fw6q 5231 5 flow flow NN cord-006870-f5w6fw6q 5231 6 ( ( -LRB- cord-006870-f5w6fw6q 5231 7 CBF CBF NNP cord-006870-f5w6fw6q 5231 8 ) ) -RRB- cord-006870-f5w6fw6q 5231 9 may may MD cord-006870-f5w6fw6q 5231 10 be be VB cord-006870-f5w6fw6q 5231 11 variably variably RB cord-006870-f5w6fw6q 5231 12 reduced reduce VBN cord-006870-f5w6fw6q 5231 13 , , , cord-006870-f5w6fw6q 5231 14 DCI DCI NNP cord-006870-f5w6fw6q 5231 15 is be VBZ cord-006870-f5w6fw6q 5231 16 more more RBR cord-006870-f5w6fw6q 5231 17 likely likely RB cord-006870-f5w6fw6q 5231 18 related relate VBN cord-006870-f5w6fw6q 5231 19 to to IN cord-006870-f5w6fw6q 5231 20 regional regional JJ cord-006870-f5w6fw6q 5231 21 impairments impairment NNS cord-006870-f5w6fw6q 5231 22 in in IN cord-006870-f5w6fw6q 5231 23 CBF CBF NNP cord-006870-f5w6fw6q 5231 24 below below IN cord-006870-f5w6fw6q 5231 25 critical critical JJ cord-006870-f5w6fw6q 5231 26 perfusion perfusion NN cord-006870-f5w6fw6q 5231 27 thresholds threshold NNS cord-006870-f5w6fw6q 5231 28 . . . cord-006870-f5w6fw6q 5232 1 We -PRON- PRP cord-006870-f5w6fw6q 5232 2 applied apply VBD cord-006870-f5w6fw6q 5232 3 volumetric volumetric JJ cord-006870-f5w6fw6q 5232 4 methods method NNS cord-006870-f5w6fw6q 5232 5 to to TO cord-006870-f5w6fw6q 5232 6 assess assess VB cord-006870-f5w6fw6q 5232 7 the the DT cord-006870-f5w6fw6q 5232 8 proportion proportion NN cord-006870-f5w6fw6q 5232 9 of of IN cord-006870-f5w6fw6q 5232 10 brain brain NN cord-006870-f5w6fw6q 5232 11 exhibiting exhibit VBG cord-006870-f5w6fw6q 5232 12 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 5232 13 ( ( -LRB- cord-006870-f5w6fw6q 5232 14 PBH PBH NNP cord-006870-f5w6fw6q 5232 15 ) ) -RRB- cord-006870-f5w6fw6q 5232 16 in in IN cord-006870-f5w6fw6q 5232 17 those those DT cord-006870-f5w6fw6q 5232 18 with with IN cord-006870-f5w6fw6q 5232 19 clinical clinical JJ cord-006870-f5w6fw6q 5232 20 DCI DCI NNP cord-006870-f5w6fw6q 5232 21 and and CC cord-006870-f5w6fw6q 5232 22 in in IN cord-006870-f5w6fw6q 5232 23 the the DT cord-006870-f5w6fw6q 5232 24 symptomatic symptomatic JJ cord-006870-f5w6fw6q 5232 25 hemisphere hemisphere NN cord-006870-f5w6fw6q 5232 26 of of IN cord-006870-f5w6fw6q 5232 27 those those DT cord-006870-f5w6fw6q 5232 28 with with IN cord-006870-f5w6fw6q 5232 29 focal focal JJ cord-006870-f5w6fw6q 5232 30 deficits deficit NNS cord-006870-f5w6fw6q 5232 31 . . . cord-006870-f5w6fw6q 5233 1 Methods method NNS cord-006870-f5w6fw6q 5233 2 61 61 CD cord-006870-f5w6fw6q 5233 3 patients patient NNS cord-006870-f5w6fw6q 5233 4 with with IN cord-006870-f5w6fw6q 5233 5 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5233 6 SAH SAH NNP cord-006870-f5w6fw6q 5233 7 underwent undergo VBD cord-006870-f5w6fw6q 5233 8 15O 15o CD cord-006870-f5w6fw6q 5233 9 - - HYPH cord-006870-f5w6fw6q 5233 10 PET pet NN cord-006870-f5w6fw6q 5233 11 and and CC cord-006870-f5w6fw6q 5233 12 CT CT NNP cord-006870-f5w6fw6q 5233 13 imaging imaging NN cord-006870-f5w6fw6q 5233 14 during during IN cord-006870-f5w6fw6q 5233 15 period period NN cord-006870-f5w6fw6q 5233 16 of of IN cord-006870-f5w6fw6q 5233 17 risk risk NN cord-006870-f5w6fw6q 5233 18 for for IN cord-006870-f5w6fw6q 5233 19 DCI DCI NNP cord-006870-f5w6fw6q 5233 20 ( ( -LRB- cord-006870-f5w6fw6q 5233 21 median median JJ cord-006870-f5w6fw6q 5233 22 8 8 CD cord-006870-f5w6fw6q 5233 23 days day NNS cord-006870-f5w6fw6q 5233 24 after after IN cord-006870-f5w6fw6q 5233 25 SAH SAH NNP cord-006870-f5w6fw6q 5233 26 , , , cord-006870-f5w6fw6q 5233 27 IQR IQR NNP cord-006870-f5w6fw6q 5233 28 7 7 CD cord-006870-f5w6fw6q 5233 29 - - SYM cord-006870-f5w6fw6q 5233 30 10 10 CD cord-006870-f5w6fw6q 5233 31 ) ) -RRB- cord-006870-f5w6fw6q 5233 32 . . . cord-006870-f5w6fw6q 5234 1 We -PRON- PRP cord-006870-f5w6fw6q 5234 2 measured measure VBD cord-006870-f5w6fw6q 5234 3 PBH PBH NNP cord-006870-f5w6fw6q 5234 4 as as IN cord-006870-f5w6fw6q 5234 5 proportion proportion NN cord-006870-f5w6fw6q 5234 6 of of IN cord-006870-f5w6fw6q 5234 7 voxels voxel NNS cord-006870-f5w6fw6q 5234 8 with with IN cord-006870-f5w6fw6q 5234 9 CBF CBF NNP cord-006870-f5w6fw6q 5234 10 < < XX cord-006870-f5w6fw6q 5234 11 25 25 CD cord-006870-f5w6fw6q 5234 12 ml/100g ml/100g CD cord-006870-f5w6fw6q 5234 13 / / SYM cord-006870-f5w6fw6q 5234 14 min min NN cord-006870-f5w6fw6q 5234 15 , , , cord-006870-f5w6fw6q 5234 16 after after IN cord-006870-f5w6fw6q 5234 17 excluding exclude VBG cord-006870-f5w6fw6q 5234 18 regions region NNS cord-006870-f5w6fw6q 5234 19 of of IN cord-006870-f5w6fw6q 5234 20 infarction infarction NN cord-006870-f5w6fw6q 5234 21 / / SYM cord-006870-f5w6fw6q 5234 22 hematoma hematoma NN cord-006870-f5w6fw6q 5234 23 on on IN cord-006870-f5w6fw6q 5234 24 CT CT NNP cord-006870-f5w6fw6q 5234 25 . . . cord-006870-f5w6fw6q 5235 1 We -PRON- PRP cord-006870-f5w6fw6q 5235 2 compared compare VBD cord-006870-f5w6fw6q 5235 3 PBH PBH NNP cord-006870-f5w6fw6q 5235 4 in in IN cord-006870-f5w6fw6q 5235 5 patients patient NNS cord-006870-f5w6fw6q 5235 6 with with IN cord-006870-f5w6fw6q 5235 7 vs. vs. NN cord-006870-f5w6fw6q 5235 8 without without IN cord-006870-f5w6fw6q 5235 9 DCI DCI NNP cord-006870-f5w6fw6q 5235 10 at at IN cord-006870-f5w6fw6q 5235 11 time time NN cord-006870-f5w6fw6q 5235 12 of of IN cord-006870-f5w6fw6q 5235 13 PET pet NN cord-006870-f5w6fw6q 5235 14 and and CC cord-006870-f5w6fw6q 5235 15 , , , cord-006870-f5w6fw6q 5235 16 in in IN cord-006870-f5w6fw6q 5235 17 those those DT cord-006870-f5w6fw6q 5235 18 with with IN cord-006870-f5w6fw6q 5235 19 focal focal JJ cord-006870-f5w6fw6q 5235 20 deficits deficit NNS cord-006870-f5w6fw6q 5235 21 , , , cord-006870-f5w6fw6q 5235 22 we -PRON- PRP cord-006870-f5w6fw6q 5235 23 compared compare VBD cord-006870-f5w6fw6q 5235 24 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 5235 25 between between IN cord-006870-f5w6fw6q 5235 26 affected affected JJ cord-006870-f5w6fw6q 5235 27 and and CC cord-006870-f5w6fw6q 5235 28 unaffected unaffected JJ cord-006870-f5w6fw6q 5235 29 hemispheres hemisphere NNS cord-006870-f5w6fw6q 5235 30 . . . cord-006870-f5w6fw6q 5236 1 PBH PBH NNP cord-006870-f5w6fw6q 5236 2 was be VBD cord-006870-f5w6fw6q 5236 3 greater great JJR cord-006870-f5w6fw6q 5236 4 in in IN cord-006870-f5w6fw6q 5236 5 the the DT cord-006870-f5w6fw6q 5236 6 23 23 CD cord-006870-f5w6fw6q 5236 7 ( ( -LRB- cord-006870-f5w6fw6q 5236 8 38 38 CD cord-006870-f5w6fw6q 5236 9 % % NN cord-006870-f5w6fw6q 5236 10 ) ) -RRB- cord-006870-f5w6fw6q 5236 11 with with IN cord-006870-f5w6fw6q 5236 12 DCI DCI NNP cord-006870-f5w6fw6q 5236 13 compared compare VBN cord-006870-f5w6fw6q 5236 14 to to IN cord-006870-f5w6fw6q 5236 15 those those DT cord-006870-f5w6fw6q 5236 16 without without IN cord-006870-f5w6fw6q 5236 17 DCI DCI NNP cord-006870-f5w6fw6q 5236 18 ( ( -LRB- cord-006870-f5w6fw6q 5236 19 20 20 CD cord-006870-f5w6fw6q 5236 20 % % NN cord-006870-f5w6fw6q 5236 21 , , , cord-006870-f5w6fw6q 5236 22 ( ( -LRB- cord-006870-f5w6fw6q 5236 23 9 9 LS cord-006870-f5w6fw6q 5236 24 ) ) -RRB- cord-006870-f5w6fw6q 5236 25 ( ( -LRB- cord-006870-f5w6fw6q 5236 26 10 10 CD cord-006870-f5w6fw6q 5236 27 ) ) -RRB- cord-006870-f5w6fw6q 5236 28 ( ( -LRB- cord-006870-f5w6fw6q 5236 29 11 11 CD cord-006870-f5w6fw6q 5236 30 ) ) -RRB- cord-006870-f5w6fw6q 5236 31 ( ( -LRB- cord-006870-f5w6fw6q 5236 32 12 12 CD cord-006870-f5w6fw6q 5236 33 ) ) -RRB- cord-006870-f5w6fw6q 5236 34 ( ( -LRB- cord-006870-f5w6fw6q 5236 35 13 13 CD cord-006870-f5w6fw6q 5236 36 ) ) -RRB- cord-006870-f5w6fw6q 5237 1 ( ( -LRB- cord-006870-f5w6fw6q 5237 2 14 14 CD cord-006870-f5w6fw6q 5237 3 ) ) -RRB- cord-006870-f5w6fw6q 5238 1 ( ( -LRB- cord-006870-f5w6fw6q 5238 2 15 15 CD cord-006870-f5w6fw6q 5238 3 ) ) -RRB- cord-006870-f5w6fw6q 5238 4 ( ( -LRB- cord-006870-f5w6fw6q 5238 5 16 16 CD cord-006870-f5w6fw6q 5238 6 ) ) -RRB- cord-006870-f5w6fw6q 5238 7 p=0 p=0 VBP cord-006870-f5w6fw6q 5238 8 .006 .006 CD cord-006870-f5w6fw6q 5238 9 ) ) -RRB- cord-006870-f5w6fw6q 5238 10 despite despite IN cord-006870-f5w6fw6q 5238 11 higher high JJR cord-006870-f5w6fw6q 5238 12 mean mean JJ cord-006870-f5w6fw6q 5238 13 arterial arterial JJ cord-006870-f5w6fw6q 5238 14 pressure pressure NN cord-006870-f5w6fw6q 5238 15 ( ( -LRB- cord-006870-f5w6fw6q 5238 16 MAP MAP NNP cord-006870-f5w6fw6q 5238 17 ) ) -RRB- cord-006870-f5w6fw6q 5238 18 and and CC cord-006870-f5w6fw6q 5238 19 most most JJS cord-006870-f5w6fw6q 5238 20 being be VBG cord-006870-f5w6fw6q 5238 21 on on IN cord-006870-f5w6fw6q 5238 22 active active JJ cord-006870-f5w6fw6q 5238 23 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 5238 24 therapies therapy NNS cord-006870-f5w6fw6q 5238 25 . . . cord-006870-f5w6fw6q 5239 1 Global global JJ cord-006870-f5w6fw6q 5239 2 CBF CBF NNP cord-006870-f5w6fw6q 5239 3 was be VBD cord-006870-f5w6fw6q 5239 4 also also RB cord-006870-f5w6fw6q 5239 5 lower low JJR cord-006870-f5w6fw6q 5239 6 in in IN cord-006870-f5w6fw6q 5239 7 those those DT cord-006870-f5w6fw6q 5239 8 with with IN cord-006870-f5w6fw6q 5239 9 DCI DCI NNP cord-006870-f5w6fw6q 5239 10 ( ( -LRB- cord-006870-f5w6fw6q 5239 11 36.0 36.0 CD cord-006870-f5w6fw6q 5239 12 vs. vs. IN cord-006870-f5w6fw6q 5239 13 44.4 44.4 CD cord-006870-f5w6fw6q 5239 14 ml/100g ml/100g CD cord-006870-f5w6fw6q 5239 15 / / SYM cord-006870-f5w6fw6q 5239 16 min min NN cord-006870-f5w6fw6q 5239 17 , , , cord-006870-f5w6fw6q 5239 18 p=0.01 p=0.01 NNP cord-006870-f5w6fw6q 5239 19 ) ) -RRB- cord-006870-f5w6fw6q 5239 20 but but CC cord-006870-f5w6fw6q 5239 21 did do VBD cord-006870-f5w6fw6q 5239 22 not not RB cord-006870-f5w6fw6q 5239 23 differ differ VB cord-006870-f5w6fw6q 5239 24 between between IN cord-006870-f5w6fw6q 5239 25 those those DT cord-006870-f5w6fw6q 5239 26 remaining remain VBG cord-006870-f5w6fw6q 5239 27 symptomatic symptomatic JJ cord-006870-f5w6fw6q 5239 28 and and CC cord-006870-f5w6fw6q 5239 29 those those DT cord-006870-f5w6fw6q 5239 30 whose whose WP$ cord-006870-f5w6fw6q 5239 31 deficits deficit NNS cord-006870-f5w6fw6q 5239 32 had have VBD cord-006870-f5w6fw6q 5239 33 resolved resolve VBN cord-006870-f5w6fw6q 5239 34 . . . cord-006870-f5w6fw6q 5240 1 While while IN cord-006870-f5w6fw6q 5240 2 mean mean VB cord-006870-f5w6fw6q 5240 3 hemispheric hemispheric JJ cord-006870-f5w6fw6q 5240 4 CBF CBF NNP cord-006870-f5w6fw6q 5240 5 was be VBD cord-006870-f5w6fw6q 5240 6 not not RB cord-006870-f5w6fw6q 5240 7 lower low JJR cord-006870-f5w6fw6q 5240 8 in in IN cord-006870-f5w6fw6q 5240 9 the the DT cord-006870-f5w6fw6q 5240 10 affected affected JJ cord-006870-f5w6fw6q 5240 11 hemispheres hemisphere NNS cord-006870-f5w6fw6q 5240 12 of of IN cord-006870-f5w6fw6q 5240 13 13 13 CD cord-006870-f5w6fw6q 5240 14 with with IN cord-006870-f5w6fw6q 5240 15 lateralizing lateralizing NN cord-006870-f5w6fw6q 5240 16 deficits deficit NNS cord-006870-f5w6fw6q 5240 17 ( ( -LRB- cord-006870-f5w6fw6q 5240 18 40.2 40.2 CD cord-006870-f5w6fw6q 5240 19 vs. vs. IN cord-006870-f5w6fw6q 5240 20 41.1 41.1 CD cord-006870-f5w6fw6q 5240 21 ml/100g ml/100g NN cord-006870-f5w6fw6q 5240 22 / / SYM cord-006870-f5w6fw6q 5240 23 min min NN cord-006870-f5w6fw6q 5240 24 , , , cord-006870-f5w6fw6q 5240 25 p=0.15 p=0.15 NNP cord-006870-f5w6fw6q 5240 26 ) ) -RRB- cord-006870-f5w6fw6q 5240 27 , , , cord-006870-f5w6fw6q 5240 28 there there EX cord-006870-f5w6fw6q 5240 29 was be VBD cord-006870-f5w6fw6q 5240 30 greater great JJR cord-006870-f5w6fw6q 5240 31 PBH PBH NNP cord-006870-f5w6fw6q 5240 32 in in IN cord-006870-f5w6fw6q 5240 33 the the DT cord-006870-f5w6fw6q 5240 34 symptomatic symptomatic JJ cord-006870-f5w6fw6q 5240 35 hemisphere hemisphere NN cord-006870-f5w6fw6q 5240 36 ( ( -LRB- cord-006870-f5w6fw6q 5240 37 21 21 CD cord-006870-f5w6fw6q 5240 38 % % NN cord-006870-f5w6fw6q 5240 39 vs. vs. CC cord-006870-f5w6fw6q 5240 40 18 18 CD cord-006870-f5w6fw6q 5240 41 % % NN cord-006870-f5w6fw6q 5240 42 , , , cord-006870-f5w6fw6q 5240 43 p=0.049 p=0.049 NNP cord-006870-f5w6fw6q 5240 44 ) ) -RRB- cord-006870-f5w6fw6q 5240 45 . . . cord-006870-f5w6fw6q 5241 1 SAH SAH NNP cord-006870-f5w6fw6q 5241 2 patients patient NNS cord-006870-f5w6fw6q 5241 3 with with IN cord-006870-f5w6fw6q 5241 4 DCI DCI NNP cord-006870-f5w6fw6q 5241 5 have have VBP cord-006870-f5w6fw6q 5241 6 a a DT cord-006870-f5w6fw6q 5241 7 greater great JJR cord-006870-f5w6fw6q 5241 8 proportion proportion NN cord-006870-f5w6fw6q 5241 9 of of IN cord-006870-f5w6fw6q 5241 10 brain brain NN cord-006870-f5w6fw6q 5241 11 with with IN cord-006870-f5w6fw6q 5241 12 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 5241 13 despite despite IN cord-006870-f5w6fw6q 5241 14 active active JJ cord-006870-f5w6fw6q 5241 15 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 5241 16 therapy therapy NN cord-006870-f5w6fw6q 5241 17 and and CC cord-006870-f5w6fw6q 5241 18 higher high JJR cord-006870-f5w6fw6q 5241 19 MAP MAP NNP cord-006870-f5w6fw6q 5241 20 . . . cord-006870-f5w6fw6q 5242 1 There there EX cord-006870-f5w6fw6q 5242 2 was be VBD cord-006870-f5w6fw6q 5242 3 also also RB cord-006870-f5w6fw6q 5242 4 larger large JJR cord-006870-f5w6fw6q 5242 5 proportion proportion NN cord-006870-f5w6fw6q 5242 6 of of IN cord-006870-f5w6fw6q 5242 7 the the DT cord-006870-f5w6fw6q 5242 8 symptomatic symptomatic JJ cord-006870-f5w6fw6q 5242 9 hemisphere hemisphere NN cord-006870-f5w6fw6q 5242 10 with with IN cord-006870-f5w6fw6q 5242 11 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 5242 12 despite despite IN cord-006870-f5w6fw6q 5242 13 no no DT cord-006870-f5w6fw6q 5242 14 asymmetry asymmetry NN cord-006870-f5w6fw6q 5242 15 of of IN cord-006870-f5w6fw6q 5242 16 hemispheric hemispheric JJ cord-006870-f5w6fw6q 5242 17 CBF CBF NNP cord-006870-f5w6fw6q 5242 18 . . . cord-006870-f5w6fw6q 5243 1 Such such JJ cord-006870-f5w6fw6q 5243 2 measurements measurement NNS cord-006870-f5w6fw6q 5243 3 of of IN cord-006870-f5w6fw6q 5243 4 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 5243 5 may may MD cord-006870-f5w6fw6q 5243 6 better better RB cord-006870-f5w6fw6q 5243 7 reflect reflect VB cord-006870-f5w6fw6q 5243 8 the the DT cord-006870-f5w6fw6q 5243 9 regional regional JJ cord-006870-f5w6fw6q 5243 10 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 5243 11 of of IN cord-006870-f5w6fw6q 5243 12 DCI DCI NNP cord-006870-f5w6fw6q 5243 13 than than IN cord-006870-f5w6fw6q 5243 14 global global JJ cord-006870-f5w6fw6q 5243 15 averaged average VBN cord-006870-f5w6fw6q 5243 16 measures measure NNS cord-006870-f5w6fw6q 5243 17 of of IN cord-006870-f5w6fw6q 5243 18 CBF CBF NNP cord-006870-f5w6fw6q 5243 19 . . . cord-006870-f5w6fw6q 5244 1 Further further JJ cord-006870-f5w6fw6q 5244 2 studies study NNS cord-006870-f5w6fw6q 5244 3 should should MD cord-006870-f5w6fw6q 5244 4 determine determine VB cord-006870-f5w6fw6q 5244 5 whether whether IN cord-006870-f5w6fw6q 5244 6 burden burden NN cord-006870-f5w6fw6q 5244 7 of of IN cord-006870-f5w6fw6q 5244 8 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 5244 9 correlates correlate VBZ cord-006870-f5w6fw6q 5244 10 with with IN cord-006870-f5w6fw6q 5244 11 tissue tissue NN cord-006870-f5w6fw6q 5244 12 and and CC cord-006870-f5w6fw6q 5244 13 patient patient JJ cord-006870-f5w6fw6q 5244 14 outcomes outcome NNS cord-006870-f5w6fw6q 5244 15 . . . cord-006870-f5w6fw6q 5245 1 Patients patient NNS cord-006870-f5w6fw6q 5245 2 who who WP cord-006870-f5w6fw6q 5245 3 survive survive VBP cord-006870-f5w6fw6q 5245 4 aneurysmal aneurysmal JJ cord-006870-f5w6fw6q 5245 5 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5245 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5245 7 ( ( -LRB- cord-006870-f5w6fw6q 5245 8 aSAH asah JJ cord-006870-f5w6fw6q 5245 9 ) ) -RRB- cord-006870-f5w6fw6q 5245 10 are be VBP cord-006870-f5w6fw6q 5245 11 often often RB cord-006870-f5w6fw6q 5245 12 burdened burden VBN cord-006870-f5w6fw6q 5245 13 with with IN cord-006870-f5w6fw6q 5245 14 lasting last VBG cord-006870-f5w6fw6q 5245 15 cognitive cognitive JJ cord-006870-f5w6fw6q 5245 16 impairment impairment NN cord-006870-f5w6fw6q 5245 17 due due IN cord-006870-f5w6fw6q 5245 18 to to IN cord-006870-f5w6fw6q 5245 19 a a DT cord-006870-f5w6fw6q 5245 20 combination combination NN cord-006870-f5w6fw6q 5245 21 of of IN cord-006870-f5w6fw6q 5245 22 sequelae sequela NNS cord-006870-f5w6fw6q 5245 23 including include VBG cord-006870-f5w6fw6q 5245 24 neuro neuro JJ cord-006870-f5w6fw6q 5245 25 - - HYPH cord-006870-f5w6fw6q 5245 26 cardiac cardiac JJ cord-006870-f5w6fw6q 5245 27 injury injury NN cord-006870-f5w6fw6q 5245 28 . . . cord-006870-f5w6fw6q 5246 1 The the DT cord-006870-f5w6fw6q 5246 2 impact impact NN cord-006870-f5w6fw6q 5246 3 of of IN cord-006870-f5w6fw6q 5246 4 neurocardiac neurocardiac NNP cord-006870-f5w6fw6q 5246 5 injury injury NN cord-006870-f5w6fw6q 5246 6 after after IN cord-006870-f5w6fw6q 5246 7 aSAH aSAH NNP cord-006870-f5w6fw6q 5246 8 is be VBZ cord-006870-f5w6fw6q 5246 9 poorly poorly RB cord-006870-f5w6fw6q 5246 10 understood understand VBN cord-006870-f5w6fw6q 5246 11 . . . cord-006870-f5w6fw6q 5247 1 This this DT cord-006870-f5w6fw6q 5247 2 study study NN cord-006870-f5w6fw6q 5247 3 sought seek VBD cord-006870-f5w6fw6q 5247 4 to to TO cord-006870-f5w6fw6q 5247 5 examine examine VB cord-006870-f5w6fw6q 5247 6 if if IN cord-006870-f5w6fw6q 5247 7 neurocardiac neurocardiac NNP cord-006870-f5w6fw6q 5247 8 injury injury NN cord-006870-f5w6fw6q 5247 9 detected detect VBN cord-006870-f5w6fw6q 5247 10 by by IN cord-006870-f5w6fw6q 5247 11 global global JJ cord-006870-f5w6fw6q 5247 12 longitudinal longitudinal JJ cord-006870-f5w6fw6q 5247 13 strain strain NN cord-006870-f5w6fw6q 5247 14 ( ( -LRB- cord-006870-f5w6fw6q 5247 15 GLS GLS NNP cord-006870-f5w6fw6q 5247 16 ) ) -RRB- cord-006870-f5w6fw6q 5247 17 is be VBZ cord-006870-f5w6fw6q 5247 18 associated associate VBN cord-006870-f5w6fw6q 5247 19 with with IN cord-006870-f5w6fw6q 5247 20 poor poor JJ cord-006870-f5w6fw6q 5247 21 performance performance NN cord-006870-f5w6fw6q 5247 22 in in IN cord-006870-f5w6fw6q 5247 23 neuropsychological neuropsychological JJ cord-006870-f5w6fw6q 5247 24 NP NP NNP cord-006870-f5w6fw6q 5247 25 memory memory NN cord-006870-f5w6fw6q 5247 26 impairment impairment NN cord-006870-f5w6fw6q 5247 27 after after IN cord-006870-f5w6fw6q 5247 28 aSAH asah JJ cord-006870-f5w6fw6q 5247 29 . . . cord-006870-f5w6fw6q 5248 1 We -PRON- PRP cord-006870-f5w6fw6q 5248 2 studied study VBD cord-006870-f5w6fw6q 5248 3 135 135 CD cord-006870-f5w6fw6q 5248 4 aSAH asah JJ cord-006870-f5w6fw6q 5248 5 patients patient NNS cord-006870-f5w6fw6q 5248 6 at at IN cord-006870-f5w6fw6q 5248 7 3 3 CD cord-006870-f5w6fw6q 5248 8 months month NNS cord-006870-f5w6fw6q 5248 9 and and CC cord-006870-f5w6fw6q 5248 10 112 112 CD cord-006870-f5w6fw6q 5248 11 at at IN cord-006870-f5w6fw6q 5248 12 12 12 CD cord-006870-f5w6fw6q 5248 13 months month NNS cord-006870-f5w6fw6q 5248 14 ( ( -LRB- cord-006870-f5w6fw6q 5248 15 SAHMII SAHMII NNP cord-006870-f5w6fw6q 5248 16 study study NN cord-006870-f5w6fw6q 5248 17 R01NR04221 R01NR04221 NNP cord-006870-f5w6fw6q 5248 18 ) ) -RRB- cord-006870-f5w6fw6q 5248 19 after after IN cord-006870-f5w6fw6q 5248 20 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5248 21 . . . cord-006870-f5w6fw6q 5249 1 Speckle speckle NN cord-006870-f5w6fw6q 5249 2 tracking tracking NN cord-006870-f5w6fw6q 5249 3 GLS GLS NNP cord-006870-f5w6fw6q 5249 4 from from IN cord-006870-f5w6fw6q 5249 5 3 3 CD cord-006870-f5w6fw6q 5249 6 apical apical JJ cord-006870-f5w6fw6q 5249 7 views view NNS cord-006870-f5w6fw6q 5249 8 were be VBD cord-006870-f5w6fw6q 5249 9 assessed assess VBN cord-006870-f5w6fw6q 5249 10 days day NNS cord-006870-f5w6fw6q 5249 11 0 0 CD cord-006870-f5w6fw6q 5249 12 - - SYM cord-006870-f5w6fw6q 5249 13 5 5 CD cord-006870-f5w6fw6q 5249 14 from from IN cord-006870-f5w6fw6q 5249 15 bleed bleed NN cord-006870-f5w6fw6q 5249 16 from from IN cord-006870-f5w6fw6q 5249 17 transthoracic transthoracic NNP cord-006870-f5w6fw6q 5249 18 echocardiograms echocardiograms NNP cord-006870-f5w6fw6q 5249 19 . . . cord-006870-f5w6fw6q 5250 1 Neuropsychological Neuropsychological NNP cord-006870-f5w6fw6q 5250 2 ( ( -LRB- cord-006870-f5w6fw6q 5250 3 NP NP NNP cord-006870-f5w6fw6q 5250 4 ) ) -RRB- cord-006870-f5w6fw6q 5250 5 outcomes outcome NNS cord-006870-f5w6fw6q 5250 6 covering cover VBG cord-006870-f5w6fw6q 5250 7 7 7 CD cord-006870-f5w6fw6q 5250 8 domains domain NNS cord-006870-f5w6fw6q 5250 9 were be VBD cord-006870-f5w6fw6q 5250 10 completed complete VBN cord-006870-f5w6fw6q 5250 11 at at IN cord-006870-f5w6fw6q 5250 12 3 3 CD cord-006870-f5w6fw6q 5250 13 and and CC cord-006870-f5w6fw6q 5250 14 12 12 CD cord-006870-f5w6fw6q 5250 15 months month NNS cord-006870-f5w6fw6q 5250 16 after after IN cord-006870-f5w6fw6q 5250 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5250 18 by by IN cord-006870-f5w6fw6q 5250 19 trained train VBN cord-006870-f5w6fw6q 5250 20 personnel personnel NNS cord-006870-f5w6fw6q 5250 21 . . . cord-006870-f5w6fw6q 5251 1 Memory memory NN cord-006870-f5w6fw6q 5251 2 tests test NNS cord-006870-f5w6fw6q 5251 3 included include VBD cord-006870-f5w6fw6q 5251 4 controlled control VBN cord-006870-f5w6fw6q 5251 5 oral oral JJ cord-006870-f5w6fw6q 5251 6 word word NN cord-006870-f5w6fw6q 5251 7 association association NN cord-006870-f5w6fw6q 5251 8 ( ( -LRB- cord-006870-f5w6fw6q 5251 9 COWA COWA NNP cord-006870-f5w6fw6q 5251 10 ) ) -RRB- cord-006870-f5w6fw6q 5251 11 , , , cord-006870-f5w6fw6q 5251 12 Wechsler Wechsler NNP cord-006870-f5w6fw6q 5251 13 memory memory NN cord-006870-f5w6fw6q 5251 14 scale scale NN cord-006870-f5w6fw6q 5251 15 ( ( -LRB- cord-006870-f5w6fw6q 5251 16 WMS WMS NNP cord-006870-f5w6fw6q 5251 17 ) ) -RRB- cord-006870-f5w6fw6q 5251 18 and and CC cord-006870-f5w6fw6q 5251 19 Rey Rey NNP cord-006870-f5w6fw6q 5251 20 auditory auditory NN cord-006870-f5w6fw6q 5251 21 ( ( -LRB- cord-006870-f5w6fw6q 5251 22 R r NN cord-006870-f5w6fw6q 5251 23 - - HYPH cord-006870-f5w6fw6q 5251 24 aud aud NN cord-006870-f5w6fw6q 5251 25 ) ) -RRB- cord-006870-f5w6fw6q 5251 26 and and CC cord-006870-f5w6fw6q 5251 27 Complex Complex NNP cord-006870-f5w6fw6q 5251 28 Figure Figure NNP cord-006870-f5w6fw6q 5251 29 ( ( -LRB- cord-006870-f5w6fw6q 5251 30 ReyC ReyC NNP cord-006870-f5w6fw6q 5251 31 ) ) -RRB- cord-006870-f5w6fw6q 5251 32 . . . cord-006870-f5w6fw6q 5252 1 ANOVA ANOVA NNP cord-006870-f5w6fw6q 5252 2 and and CC cord-006870-f5w6fw6q 5252 3 Kruskal Kruskal NNP cord-006870-f5w6fw6q 5252 4 - - HYPH cord-006870-f5w6fw6q 5252 5 Wallis Wallis NNP cord-006870-f5w6fw6q 5252 6 , , , cord-006870-f5w6fw6q 5252 7 Pearson Pearson NNP cord-006870-f5w6fw6q 5252 8 and and CC cord-006870-f5w6fw6q 5252 9 Spearman Spearman NNP cord-006870-f5w6fw6q 5252 10 correlations correlation NNS cord-006870-f5w6fw6q 5252 11 and and CC cord-006870-f5w6fw6q 5252 12 logistic logistic JJ cord-006870-f5w6fw6q 5252 13 regression regression NN cord-006870-f5w6fw6q 5252 14 were be VBD cord-006870-f5w6fw6q 5252 15 completed complete VBN cord-006870-f5w6fw6q 5252 16 using use VBG cord-006870-f5w6fw6q 5252 17 SPSS SPSS NNP cord-006870-f5w6fw6q 5252 18 and and CC cord-006870-f5w6fw6q 5252 19 SAS SAS NNP cord-006870-f5w6fw6q 5252 20 . . . cord-006870-f5w6fw6q 5253 1 There there EX cord-006870-f5w6fw6q 5253 2 were be VBD cord-006870-f5w6fw6q 5253 3 30 30 CD cord-006870-f5w6fw6q 5253 4 ( ( -LRB- cord-006870-f5w6fw6q 5253 5 22 22 CD cord-006870-f5w6fw6q 5253 6 % % NN cord-006870-f5w6fw6q 5253 7 ) ) -RRB- cord-006870-f5w6fw6q 5253 8 patients patient NNS cord-006870-f5w6fw6q 5253 9 with with IN cord-006870-f5w6fw6q 5253 10 abnormal abnormal JJ cord-006870-f5w6fw6q 5253 11 GLS GLS NNP cord-006870-f5w6fw6q 5253 12 ( ( -LRB- cord-006870-f5w6fw6q 5253 13 defined define VBN cord-006870-f5w6fw6q 5253 14 as as IN cord-006870-f5w6fw6q 5253 15 > > XX cord-006870-f5w6fw6q 5253 16 -17 -17 CD cord-006870-f5w6fw6q 5253 17 % % NN cord-006870-f5w6fw6q 5253 18 ) ) -RRB- cord-006870-f5w6fw6q 5253 19 and and CC cord-006870-f5w6fw6q 5253 20 27 27 CD cord-006870-f5w6fw6q 5253 21 ( ( -LRB- cord-006870-f5w6fw6q 5253 22 24 24 CD cord-006870-f5w6fw6q 5253 23 % % NN cord-006870-f5w6fw6q 5253 24 ) ) -RRB- cord-006870-f5w6fw6q 5253 25 in in IN cord-006870-f5w6fw6q 5253 26 the the DT cord-006870-f5w6fw6q 5253 27 3 3 CD cord-006870-f5w6fw6q 5253 28 and and CC cord-006870-f5w6fw6q 5253 29 12 12 CD cord-006870-f5w6fw6q 5253 30 months month NNS cord-006870-f5w6fw6q 5253 31 groups group NNS cord-006870-f5w6fw6q 5253 32 respectively respectively RB cord-006870-f5w6fw6q 5253 33 . . . cord-006870-f5w6fw6q 5254 1 GLS GLS NNP cord-006870-f5w6fw6q 5254 2 groups group NNS cord-006870-f5w6fw6q 5254 3 had have VBD cord-006870-f5w6fw6q 5254 4 similar similar JJ cord-006870-f5w6fw6q 5254 5 age age NN cord-006870-f5w6fw6q 5254 6 , , , cord-006870-f5w6fw6q 5254 7 gender gender NN cord-006870-f5w6fw6q 5254 8 and and CC cord-006870-f5w6fw6q 5254 9 fisher fisher NNP cord-006870-f5w6fw6q 5254 10 grade grade NN cord-006870-f5w6fw6q 5254 11 . . . cord-006870-f5w6fw6q 5255 1 Abnormal abnormal JJ cord-006870-f5w6fw6q 5255 2 GLS GLS NNP cord-006870-f5w6fw6q 5255 3 was be VBD cord-006870-f5w6fw6q 5255 4 associated associate VBN cord-006870-f5w6fw6q 5255 5 with with IN cord-006870-f5w6fw6q 5255 6 higher high JJR cord-006870-f5w6fw6q 5255 7 HH hh NN cord-006870-f5w6fw6q 5255 8 at at IN cord-006870-f5w6fw6q 5255 9 3 3 CD cord-006870-f5w6fw6q 5255 10 ( ( -LRB- cord-006870-f5w6fw6q 5255 11 p=.05 p=.05 NNP cord-006870-f5w6fw6q 5255 12 ) ) -RRB- cord-006870-f5w6fw6q 5255 13 and and CC cord-006870-f5w6fw6q 5255 14 12 12 CD cord-006870-f5w6fw6q 5255 15 ( ( -LRB- cord-006870-f5w6fw6q 5255 16 p=.002 p=.002 NNS cord-006870-f5w6fw6q 5255 17 ) ) -RRB- cord-006870-f5w6fw6q 5255 18 months month NNS cord-006870-f5w6fw6q 5255 19 . . . cord-006870-f5w6fw6q 5256 1 Abnormal abnormal JJ cord-006870-f5w6fw6q 5256 2 GLS GLS NNP cord-006870-f5w6fw6q 5256 3 was be VBD cord-006870-f5w6fw6q 5256 4 significantly significantly RB cord-006870-f5w6fw6q 5256 5 associated associate VBN cord-006870-f5w6fw6q 5256 6 with with IN cord-006870-f5w6fw6q 5256 7 decreased decreased JJ cord-006870-f5w6fw6q 5256 8 performance performance NN cord-006870-f5w6fw6q 5256 9 in in IN cord-006870-f5w6fw6q 5256 10 R r NN cord-006870-f5w6fw6q 5256 11 - - HYPH cord-006870-f5w6fw6q 5256 12 aud aud VBG cord-006870-f5w6fw6q 5256 13 memory memory NN cord-006870-f5w6fw6q 5256 14 domains domain NNS cord-006870-f5w6fw6q 5256 15 at at IN cord-006870-f5w6fw6q 5256 16 3 3 CD cord-006870-f5w6fw6q 5256 17 months month NNS cord-006870-f5w6fw6q 5256 18 ( ( -LRB- cord-006870-f5w6fw6q 5256 19 p=.013 p=.013 NN cord-006870-f5w6fw6q 5256 20 ) ) -RRB- cord-006870-f5w6fw6q 5256 21 and and CC cord-006870-f5w6fw6q 5256 22 12 12 CD cord-006870-f5w6fw6q 5256 23 months month NNS cord-006870-f5w6fw6q 5256 24 ( ( -LRB- cord-006870-f5w6fw6q 5256 25 p=.027 p=.027 NNP cord-006870-f5w6fw6q 5256 26 ) ) -RRB- cord-006870-f5w6fw6q 5256 27 after after IN cord-006870-f5w6fw6q 5256 28 aSAH asah JJ cord-006870-f5w6fw6q 5256 29 and and CC cord-006870-f5w6fw6q 5256 30 even even RB cord-006870-f5w6fw6q 5256 31 when when WRB cord-006870-f5w6fw6q 5256 32 controlling control VBG cord-006870-f5w6fw6q 5256 33 for for IN cord-006870-f5w6fw6q 5256 34 age age NN cord-006870-f5w6fw6q 5256 35 and and CC cord-006870-f5w6fw6q 5256 36 HH hh NN cord-006870-f5w6fw6q 5256 37 at at IN cord-006870-f5w6fw6q 5256 38 3 3 CD cord-006870-f5w6fw6q 5256 39 months month NNS cord-006870-f5w6fw6q 5256 40 ( ( -LRB- cord-006870-f5w6fw6q 5256 41 p=.010 p=.010 NNP cord-006870-f5w6fw6q 5256 42 ) ) -RRB- cord-006870-f5w6fw6q 5256 43 . . . cord-006870-f5w6fw6q 5257 1 GLS<-17 GLS<-17 NNP cord-006870-f5w6fw6q 5257 2 was be VBD cord-006870-f5w6fw6q 5257 3 associated associate VBN cord-006870-f5w6fw6q 5257 4 with with IN cord-006870-f5w6fw6q 5257 5 poor poor JJ cord-006870-f5w6fw6q 5257 6 memory memory NN cord-006870-f5w6fw6q 5257 7 performance performance NN cord-006870-f5w6fw6q 5257 8 12 12 CD cord-006870-f5w6fw6q 5257 9 months month NNS cord-006870-f5w6fw6q 5257 10 after after IN cord-006870-f5w6fw6q 5257 11 aSAH asah JJ cord-006870-f5w6fw6q 5257 12 in in IN cord-006870-f5w6fw6q 5257 13 COWA COWA NNP cord-006870-f5w6fw6q 5257 14 ( ( -LRB- cord-006870-f5w6fw6q 5257 15 p=.008 p=.008 NNP cord-006870-f5w6fw6q 5257 16 ) ) -RRB- cord-006870-f5w6fw6q 5257 17 and and CC cord-006870-f5w6fw6q 5257 18 the the DT cord-006870-f5w6fw6q 5257 19 WMS WMS NNP cord-006870-f5w6fw6q 5257 20 ( ( -LRB- cord-006870-f5w6fw6q 5257 21 p=.02 p=.02 NNP cord-006870-f5w6fw6q 5257 22 ) ) -RRB- cord-006870-f5w6fw6q 5257 23 even even RB cord-006870-f5w6fw6q 5257 24 after after IN cord-006870-f5w6fw6q 5257 25 adjusting adjust VBG cord-006870-f5w6fw6q 5257 26 for for IN cord-006870-f5w6fw6q 5257 27 age age NN cord-006870-f5w6fw6q 5257 28 and and CC cord-006870-f5w6fw6q 5257 29 HH hh NN cord-006870-f5w6fw6q 5257 30 , , , cord-006870-f5w6fw6q 5257 31 COWA COWA NNP cord-006870-f5w6fw6q 5257 32 ( ( -LRB- cord-006870-f5w6fw6q 5257 33 p=.008 p=.008 NNP cord-006870-f5w6fw6q 5257 34 ) ) -RRB- cord-006870-f5w6fw6q 5257 35 and and CC cord-006870-f5w6fw6q 5257 36 WMS WMS NNP cord-006870-f5w6fw6q 5257 37 ( ( -LRB- cord-006870-f5w6fw6q 5257 38 .018 .018 CD cord-006870-f5w6fw6q 5257 39 ) ) -RRB- cord-006870-f5w6fw6q 5257 40 . . . cord-006870-f5w6fw6q 5258 1 Neuro Neuro NNP cord-006870-f5w6fw6q 5258 2 - - HYPH cord-006870-f5w6fw6q 5258 3 cardiac cardiac JJ cord-006870-f5w6fw6q 5258 4 injury injury NN cord-006870-f5w6fw6q 5258 5 detected detect VBN cord-006870-f5w6fw6q 5258 6 by by IN cord-006870-f5w6fw6q 5258 7 GLS GLS NNP cord-006870-f5w6fw6q 5258 8 was be VBD cord-006870-f5w6fw6q 5258 9 associated associate VBN cord-006870-f5w6fw6q 5258 10 with with IN cord-006870-f5w6fw6q 5258 11 decreased decreased JJ cord-006870-f5w6fw6q 5258 12 performance performance NN cord-006870-f5w6fw6q 5258 13 in in IN cord-006870-f5w6fw6q 5258 14 memory memory NN cord-006870-f5w6fw6q 5258 15 domains domain NNS cord-006870-f5w6fw6q 5258 16 of of IN cord-006870-f5w6fw6q 5258 17 NP NP NNP cord-006870-f5w6fw6q 5258 18 function function NN cord-006870-f5w6fw6q 5258 19 at at IN cord-006870-f5w6fw6q 5258 20 3 3 CD cord-006870-f5w6fw6q 5258 21 and and CC cord-006870-f5w6fw6q 5258 22 12 12 CD cord-006870-f5w6fw6q 5258 23 months month NNS cord-006870-f5w6fw6q 5258 24 after after IN cord-006870-f5w6fw6q 5258 25 aSAH asah JJ cord-006870-f5w6fw6q 5258 26 . . . cord-006870-f5w6fw6q 5259 1 While while IN cord-006870-f5w6fw6q 5259 2 these these DT cord-006870-f5w6fw6q 5259 3 relationships relationship NNS cord-006870-f5w6fw6q 5259 4 require require VBP cord-006870-f5w6fw6q 5259 5 further further JJ cord-006870-f5w6fw6q 5259 6 examination examination NN cord-006870-f5w6fw6q 5259 7 , , , cord-006870-f5w6fw6q 5259 8 neurocardiac neurocardiac NNP cord-006870-f5w6fw6q 5259 9 injury injury NN cord-006870-f5w6fw6q 5259 10 may may MD cord-006870-f5w6fw6q 5259 11 contribute contribute VB cord-006870-f5w6fw6q 5259 12 to to IN cord-006870-f5w6fw6q 5259 13 long long JJ cord-006870-f5w6fw6q 5259 14 term term NN cord-006870-f5w6fw6q 5259 15 NP NP NNP cord-006870-f5w6fw6q 5259 16 impairment impairment NN cord-006870-f5w6fw6q 5259 17 after after IN cord-006870-f5w6fw6q 5259 18 aSAH asah JJ cord-006870-f5w6fw6q 5259 19 . . . cord-006870-f5w6fw6q 5260 1 Delayed delay VBN cord-006870-f5w6fw6q 5260 2 Cerebral cerebral JJ cord-006870-f5w6fw6q 5260 3 infarction infarction NN cord-006870-f5w6fw6q 5260 4 ( ( -LRB- cord-006870-f5w6fw6q 5260 5 DCI DCI NNP cord-006870-f5w6fw6q 5260 6 ) ) -RRB- cord-006870-f5w6fw6q 5260 7 is be VBZ cord-006870-f5w6fw6q 5260 8 a a DT cord-006870-f5w6fw6q 5260 9 frequent frequent JJ cord-006870-f5w6fw6q 5260 10 complication complication NN cord-006870-f5w6fw6q 5260 11 following follow VBG cord-006870-f5w6fw6q 5260 12 high high JJ cord-006870-f5w6fw6q 5260 13 - - HYPH cord-006870-f5w6fw6q 5260 14 grade grade NN cord-006870-f5w6fw6q 5260 15 aneurysmal aneurysmal NN cord-006870-f5w6fw6q 5260 16 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5260 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5260 18 ( ( -LRB- cord-006870-f5w6fw6q 5260 19 aSAH asah JJ cord-006870-f5w6fw6q 5260 20 ) ) -RRB- cord-006870-f5w6fw6q 5260 21 . . . cord-006870-f5w6fw6q 5261 1 Management Management NNP cord-006870-f5w6fw6q 5261 2 of of IN cord-006870-f5w6fw6q 5261 3 DCI DCI NNP cord-006870-f5w6fw6q 5261 4 includes include VBZ cord-006870-f5w6fw6q 5261 5 maintaining maintain VBG cord-006870-f5w6fw6q 5261 6 hypertension hypertension NN cord-006870-f5w6fw6q 5261 7 , , , cord-006870-f5w6fw6q 5261 8 which which WDT cord-006870-f5w6fw6q 5261 9 is be VBZ cord-006870-f5w6fw6q 5261 10 challenging challenge VBG cord-006870-f5w6fw6q 5261 11 in in IN cord-006870-f5w6fw6q 5261 12 heavily heavily RB cord-006870-f5w6fw6q 5261 13 sedate sedate JJ cord-006870-f5w6fw6q 5261 14 patients patient NNS cord-006870-f5w6fw6q 5261 15 . . . cord-006870-f5w6fw6q 5262 1 Ketamine Ketamine NNP cord-006870-f5w6fw6q 5262 2 is be VBZ cord-006870-f5w6fw6q 5262 3 a a DT cord-006870-f5w6fw6q 5262 4 hemodynamically hemodynamically RB cord-006870-f5w6fw6q 5262 5 stable stable JJ cord-006870-f5w6fw6q 5262 6 , , , cord-006870-f5w6fw6q 5262 7 analgesic analgesic JJ cord-006870-f5w6fw6q 5262 8 sedative sedative NN cord-006870-f5w6fw6q 5262 9 not not RB cord-006870-f5w6fw6q 5262 10 studied study VBN cord-006870-f5w6fw6q 5262 11 in in IN cord-006870-f5w6fw6q 5262 12 this this DT cord-006870-f5w6fw6q 5262 13 population population NN cord-006870-f5w6fw6q 5262 14 . . . cord-006870-f5w6fw6q 5263 1 We -PRON- PRP cord-006870-f5w6fw6q 5263 2 hypothesize hypothesize VBP cord-006870-f5w6fw6q 5263 3 that that IN cord-006870-f5w6fw6q 5263 4 Ketamine Ketamine NNP cord-006870-f5w6fw6q 5263 5 infusion infusion NN cord-006870-f5w6fw6q 5263 6 ( ( -LRB- cord-006870-f5w6fw6q 5263 7 K K NNP cord-006870-f5w6fw6q 5263 8 ) ) -RRB- cord-006870-f5w6fw6q 5263 9 , , , cord-006870-f5w6fw6q 5263 10 as as IN cord-006870-f5w6fw6q 5263 11 compared compare VBN cord-006870-f5w6fw6q 5263 12 to to IN cord-006870-f5w6fw6q 5263 13 traditional traditional JJ cord-006870-f5w6fw6q 5263 14 sedatives sedative NNS cord-006870-f5w6fw6q 5263 15 ( ( -LRB- cord-006870-f5w6fw6q 5263 16 control control NN cord-006870-f5w6fw6q 5263 17 ) ) -RRB- cord-006870-f5w6fw6q 5263 18 , , , cord-006870-f5w6fw6q 5263 19 will will MD cord-006870-f5w6fw6q 5263 20 safely safely RB cord-006870-f5w6fw6q 5263 21 improve improve VB cord-006870-f5w6fw6q 5263 22 the the DT cord-006870-f5w6fw6q 5263 23 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 5263 24 profile profile NN cord-006870-f5w6fw6q 5263 25 in in IN cord-006870-f5w6fw6q 5263 26 high high JJ cord-006870-f5w6fw6q 5263 27 grade grade NN cord-006870-f5w6fw6q 5263 28 ventilated ventilate VBN cord-006870-f5w6fw6q 5263 29 aSAH asah JJ cord-006870-f5w6fw6q 5263 30 patients patient NNS cord-006870-f5w6fw6q 5264 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 5264 2 review review NN cord-006870-f5w6fw6q 5264 3 of of IN cord-006870-f5w6fw6q 5264 4 aSAH asah JJ cord-006870-f5w6fw6q 5264 5 patients patient NNS cord-006870-f5w6fw6q 5264 6 admitted admit VBD cord-006870-f5w6fw6q 5264 7 1/2015 1/2015 CD cord-006870-f5w6fw6q 5264 8 to to IN cord-006870-f5w6fw6q 5264 9 2/2017 2/2017 CD cord-006870-f5w6fw6q 5264 10 requiring require VBG cord-006870-f5w6fw6q 5264 11 mechanical mechanical JJ cord-006870-f5w6fw6q 5264 12 Delayed Delayed NNP cord-006870-f5w6fw6q 5264 13 Cerebral cerebral JJ cord-006870-f5w6fw6q 5264 14 infarction infarction NN cord-006870-f5w6fw6q 5264 15 ( ( -LRB- cord-006870-f5w6fw6q 5264 16 DCI DCI NNP cord-006870-f5w6fw6q 5264 17 ) ) -RRB- cord-006870-f5w6fw6q 5264 18 is be VBZ cord-006870-f5w6fw6q 5264 19 a a DT cord-006870-f5w6fw6q 5264 20 frequent frequent JJ cord-006870-f5w6fw6q 5264 21 complication complication NN cord-006870-f5w6fw6q 5264 22 following follow VBG cord-006870-f5w6fw6q 5264 23 high high JJ cord-006870-f5w6fw6q 5264 24 - - HYPH cord-006870-f5w6fw6q 5264 25 grade grade NN cord-006870-f5w6fw6q 5264 26 aneurysmal aneurysmal NN cord-006870-f5w6fw6q 5264 27 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5264 28 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5264 29 ( ( -LRB- cord-006870-f5w6fw6q 5264 30 aSAH asah JJ cord-006870-f5w6fw6q 5264 31 ) ) -RRB- cord-006870-f5w6fw6q 5264 32 . . . cord-006870-f5w6fw6q 5265 1 Management Management NNP cord-006870-f5w6fw6q 5265 2 of of IN cord-006870-f5w6fw6q 5265 3 DCI DCI NNP cord-006870-f5w6fw6q 5265 4 includes include VBZ cord-006870-f5w6fw6q 5265 5 maintaining maintain VBG cord-006870-f5w6fw6q 5265 6 hypertension hypertension NN cord-006870-f5w6fw6q 5265 7 , , , cord-006870-f5w6fw6q 5265 8 which which WDT cord-006870-f5w6fw6q 5265 9 is be VBZ cord-006870-f5w6fw6q 5265 10 challenging challenge VBG cord-006870-f5w6fw6q 5265 11 in in IN cord-006870-f5w6fw6q 5265 12 heavily heavily RB cord-006870-f5w6fw6q 5265 13 sedate sedate JJ cord-006870-f5w6fw6q 5265 14 patients patient NNS cord-006870-f5w6fw6q 5265 15 . . . cord-006870-f5w6fw6q 5266 1 Ketamine Ketamine NNP cord-006870-f5w6fw6q 5266 2 is be VBZ cord-006870-f5w6fw6q 5266 3 a a DT cord-006870-f5w6fw6q 5266 4 hemodynamically hemodynamically RB cord-006870-f5w6fw6q 5266 5 stable stable JJ cord-006870-f5w6fw6q 5266 6 , , , cord-006870-f5w6fw6q 5266 7 analgesic analgesic JJ cord-006870-f5w6fw6q 5266 8 sedative sedative NN cord-006870-f5w6fw6q 5266 9 not not RB cord-006870-f5w6fw6q 5266 10 studied study VBN cord-006870-f5w6fw6q 5266 11 in in IN cord-006870-f5w6fw6q 5266 12 this this DT cord-006870-f5w6fw6q 5266 13 population population NN cord-006870-f5w6fw6q 5266 14 . . . cord-006870-f5w6fw6q 5267 1 ventilation ventilation NN cord-006870-f5w6fw6q 5267 2 > > XX cord-006870-f5w6fw6q 5267 3 72 72 CD cord-006870-f5w6fw6q 5267 4 hrs hrs NN cord-006870-f5w6fw6q 5267 5 , , , cord-006870-f5w6fw6q 5267 6 and and CC cord-006870-f5w6fw6q 5267 7 without without IN cord-006870-f5w6fw6q 5267 8 DNR DNR NNP cord-006870-f5w6fw6q 5267 9 within within IN cord-006870-f5w6fw6q 5267 10 48 48 CD cord-006870-f5w6fw6q 5267 11 hrs hrs NN cord-006870-f5w6fw6q 5267 12 from from IN cord-006870-f5w6fw6q 5267 13 admission admission NN cord-006870-f5w6fw6q 5267 14 . . . cord-006870-f5w6fw6q 5268 1 We -PRON- PRP cord-006870-f5w6fw6q 5268 2 assessed assess VBD cord-006870-f5w6fw6q 5268 3 demographics demographic NNS cord-006870-f5w6fw6q 5268 4 , , , cord-006870-f5w6fw6q 5268 5 hemodynamics hemodynamic NNS cord-006870-f5w6fw6q 5268 6 , , , cord-006870-f5w6fw6q 5268 7 pressor pressor NN cord-006870-f5w6fw6q 5268 8 , , , cord-006870-f5w6fw6q 5268 9 DCI DCI NNP cord-006870-f5w6fw6q 5268 10 at at IN cord-006870-f5w6fw6q 5268 11 2 2 CD cord-006870-f5w6fw6q 5268 12 weeks week NNS cord-006870-f5w6fw6q 5268 13 , , , cord-006870-f5w6fw6q 5268 14 ventilator ventilator NN cord-006870-f5w6fw6q 5268 15 and and CC cord-006870-f5w6fw6q 5268 16 ICU ICU NNP cord-006870-f5w6fw6q 5268 17 LOS LOS NNP cord-006870-f5w6fw6q 5268 18 , , , cord-006870-f5w6fw6q 5268 19 and and CC cord-006870-f5w6fw6q 5268 20 mortality mortality NN cord-006870-f5w6fw6q 5268 21 . . . cord-006870-f5w6fw6q 5269 1 Fisher Fisher NNP cord-006870-f5w6fw6q 5269 2 Exact Exact NNP cord-006870-f5w6fw6q 5269 3 , , , cord-006870-f5w6fw6q 5269 4 Wilcoxon Wilcoxon NNP cord-006870-f5w6fw6q 5269 5 , , , cord-006870-f5w6fw6q 5269 6 and and CC cord-006870-f5w6fw6q 5269 7 Paired Paired NNP cord-006870-f5w6fw6q 5269 8 T T NNP cord-006870-f5w6fw6q 5269 9 - - HYPH cord-006870-f5w6fw6q 5269 10 Test Test NNP cord-006870-f5w6fw6q 5269 11 applied apply VBD cord-006870-f5w6fw6q 5269 12 . . . cord-006870-f5w6fw6q 5270 1 Comparing compare VBG cord-006870-f5w6fw6q 5270 2 K K NNP cord-006870-f5w6fw6q 5270 3 ( ( -LRB- cord-006870-f5w6fw6q 5270 4 n=16 n=16 NNP cord-006870-f5w6fw6q 5270 5 ) ) -RRB- cord-006870-f5w6fw6q 5270 6 vs vs IN cord-006870-f5w6fw6q 5270 7 control control NNP cord-006870-f5w6fw6q 5270 8 ( ( -LRB- cord-006870-f5w6fw6q 5270 9 n=19 n=19 NNP cord-006870-f5w6fw6q 5270 10 ) ) -RRB- cord-006870-f5w6fw6q 5270 11 , , , cord-006870-f5w6fw6q 5270 12 median median NN cord-006870-f5w6fw6q 5270 13 ( ( -LRB- cord-006870-f5w6fw6q 5270 14 Q1 Q1 NNP cord-006870-f5w6fw6q 5270 15 , , , cord-006870-f5w6fw6q 5270 16 Q3 Q3 NNP cord-006870-f5w6fw6q 5270 17 ) ) -RRB- cord-006870-f5w6fw6q 5270 18 results result VBZ cord-006870-f5w6fw6q 5270 19 for for IN cord-006870-f5w6fw6q 5270 20 : : : cord-006870-f5w6fw6q 5271 1 Age age NN cord-006870-f5w6fw6q 5271 2 59 59 CD cord-006870-f5w6fw6q 5271 3 ( ( -LRB- cord-006870-f5w6fw6q 5271 4 48 48 CD cord-006870-f5w6fw6q 5271 5 , , , cord-006870-f5w6fw6q 5271 6 67 67 CD cord-006870-f5w6fw6q 5271 7 ) ) -RRB- cord-006870-f5w6fw6q 5271 8 vs vs IN cord-006870-f5w6fw6q 5271 9 59 59 CD cord-006870-f5w6fw6q 5271 10 ( ( -LRB- cord-006870-f5w6fw6q 5271 11 48 48 CD cord-006870-f5w6fw6q 5271 12 , , , cord-006870-f5w6fw6q 5271 13 72 72 CD cord-006870-f5w6fw6q 5271 14 ) ) -RRB- cord-006870-f5w6fw6q 5271 15 ; ; : cord-006870-f5w6fw6q 5271 16 Hunt Hunt NNP cord-006870-f5w6fw6q 5271 17 and and CC cord-006870-f5w6fw6q 5271 18 Hess Hess NNP cord-006870-f5w6fw6q 5271 19 4 4 CD cord-006870-f5w6fw6q 5271 20 ( ( -LRB- cord-006870-f5w6fw6q 5271 21 3 3 CD cord-006870-f5w6fw6q 5271 22 , , , cord-006870-f5w6fw6q 5271 23 5 5 CD cord-006870-f5w6fw6q 5271 24 ) ) -RRB- cord-006870-f5w6fw6q 5271 25 vs. vs. NN cord-006870-f5w6fw6q 5271 26 4 4 CD cord-006870-f5w6fw6q 5271 27 ( ( -LRB- cord-006870-f5w6fw6q 5271 28 3 3 CD cord-006870-f5w6fw6q 5271 29 , , , cord-006870-f5w6fw6q 5271 30 4 4 CD cord-006870-f5w6fw6q 5271 31 ) ) -RRB- cord-006870-f5w6fw6q 5271 32 ; ; : cord-006870-f5w6fw6q 5271 33 MPM-3 MPM-3 NNP cord-006870-f5w6fw6q 5271 34 30 30 CD cord-006870-f5w6fw6q 5271 35 day day NN cord-006870-f5w6fw6q 5271 36 estimated estimate VBN cord-006870-f5w6fw6q 5271 37 mortality mortality NN cord-006870-f5w6fw6q 5271 38 27 27 CD cord-006870-f5w6fw6q 5271 39 . . . cord-006870-f5w6fw6q 5272 1 8 8 CD cord-006870-f5w6fw6q 5272 2 % % NN cord-006870-f5w6fw6q 5272 3 vs. vs. CC cord-006870-f5w6fw6q 5272 4 28.5 28.5 CD cord-006870-f5w6fw6q 5272 5 % % NN cord-006870-f5w6fw6q 5272 6 ; ; , cord-006870-f5w6fw6q 5272 7 and and CC cord-006870-f5w6fw6q 5272 8 GCS GCS NNP cord-006870-f5w6fw6q 5272 9 7 7 CD cord-006870-f5w6fw6q 5272 10 ( ( -LRB- cord-006870-f5w6fw6q 5272 11 6 6 CD cord-006870-f5w6fw6q 5272 12 , , , cord-006870-f5w6fw6q 5272 13 9 9 CD cord-006870-f5w6fw6q 5272 14 ) ) -RRB- cord-006870-f5w6fw6q 5273 1 vs vs IN cord-006870-f5w6fw6q 5273 2 7 7 CD cord-006870-f5w6fw6q 5273 3 ( ( -LRB- cord-006870-f5w6fw6q 5273 4 5 5 CD cord-006870-f5w6fw6q 5273 5 , , , cord-006870-f5w6fw6q 5273 6 8) 8) NN cord-006870-f5w6fw6q 5273 7 . . . cord-006870-f5w6fw6q 5274 1 Ketamine Ketamine NNP cord-006870-f5w6fw6q 5274 2 initiated initiate VBD cord-006870-f5w6fw6q 5274 3 on on IN cord-006870-f5w6fw6q 5274 4 day day NN cord-006870-f5w6fw6q 5274 5 4 4 CD cord-006870-f5w6fw6q 5274 6 ( ( -LRB- cord-006870-f5w6fw6q 5274 7 2 2 CD cord-006870-f5w6fw6q 5274 8 , , , cord-006870-f5w6fw6q 5274 9 5 5 CD cord-006870-f5w6fw6q 5274 10 ) ) -RRB- cord-006870-f5w6fw6q 5274 11 ; ; : cord-006870-f5w6fw6q 5274 12 ICU ICU NNP cord-006870-f5w6fw6q 5274 13 LOS LOS NNP cord-006870-f5w6fw6q 5274 14 20 20 CD cord-006870-f5w6fw6q 5274 15 ( ( -LRB- cord-006870-f5w6fw6q 5274 16 17 17 CD cord-006870-f5w6fw6q 5274 17 , , , cord-006870-f5w6fw6q 5274 18 24 24 CD cord-006870-f5w6fw6q 5274 19 ) ) -RRB- cord-006870-f5w6fw6q 5274 20 vs. vs. FW cord-006870-f5w6fw6q 5274 21 15 15 CD cord-006870-f5w6fw6q 5274 22 ( ( -LRB- cord-006870-f5w6fw6q 5274 23 7 7 CD cord-006870-f5w6fw6q 5274 24 , , , cord-006870-f5w6fw6q 5274 25 22 22 CD cord-006870-f5w6fw6q 5274 26 ) ) -RRB- cord-006870-f5w6fw6q 5274 27 ; ; : cord-006870-f5w6fw6q 5274 28 and and CC cord-006870-f5w6fw6q 5274 29 Vent Vent NNP cord-006870-f5w6fw6q 5274 30 LOS LOS NNP cord-006870-f5w6fw6q 5274 31 17 17 CD cord-006870-f5w6fw6q 5274 32 ( ( -LRB- cord-006870-f5w6fw6q 5274 33 12 12 CD cord-006870-f5w6fw6q 5274 34 , , , cord-006870-f5w6fw6q 5274 35 29 29 CD cord-006870-f5w6fw6q 5274 36 ) ) -RRB- cord-006870-f5w6fw6q 5274 37 vs. vs. NN cord-006870-f5w6fw6q 5274 38 11 11 CD cord-006870-f5w6fw6q 5274 39 ( ( -LRB- cord-006870-f5w6fw6q 5274 40 8 8 CD cord-006870-f5w6fw6q 5274 41 , , , cord-006870-f5w6fw6q 5274 42 28 28 CD cord-006870-f5w6fw6q 5274 43 ) ) -RRB- cord-006870-f5w6fw6q 5274 44 . . . cord-006870-f5w6fw6q 5275 1 Mean mean JJ cord-006870-f5w6fw6q 5275 2 ( ( -LRB- cord-006870-f5w6fw6q 5275 3 SD sd NN cord-006870-f5w6fw6q 5275 4 + + CC cord-006870-f5w6fw6q 5275 5 /- /- . cord-006870-f5w6fw6q 5275 6 ) ) -RRB- cord-006870-f5w6fw6q 5276 1 for for IN cord-006870-f5w6fw6q 5276 2 8 8 CD cord-006870-f5w6fw6q 5276 3 hours hour NNS cord-006870-f5w6fw6q 5276 4 before before RB cord-006870-f5w6fw6q 5276 5 and and CC cord-006870-f5w6fw6q 5276 6 after after IN cord-006870-f5w6fw6q 5276 7 ketamine ketamine NN cord-006870-f5w6fw6q 5276 8 : : : cord-006870-f5w6fw6q 5276 9 MAP MAP NNP cord-006870-f5w6fw6q 5276 10 93 93 CD cord-006870-f5w6fw6q 5276 11 ( ( -LRB- cord-006870-f5w6fw6q 5276 12 11 11 CD cord-006870-f5w6fw6q 5276 13 ) ) -RRB- cord-006870-f5w6fw6q 5276 14 vs vs IN cord-006870-f5w6fw6q 5276 15 99 99 CD cord-006870-f5w6fw6q 5276 16 ( ( -LRB- cord-006870-f5w6fw6q 5276 17 15 15 CD cord-006870-f5w6fw6q 5276 18 ) ) -RRB- cord-006870-f5w6fw6q 5276 19 , , , cord-006870-f5w6fw6q 5276 20 p p NN cord-006870-f5w6fw6q 5276 21 0.05 0.05 CD cord-006870-f5w6fw6q 5276 22 , , , cord-006870-f5w6fw6q 5276 23 except except IN cord-006870-f5w6fw6q 5276 24 where where WRB cord-006870-f5w6fw6q 5276 25 noted note VBN cord-006870-f5w6fw6q 5276 26 . . . cord-006870-f5w6fw6q 5277 1 Ketamine Ketamine NNP cord-006870-f5w6fw6q 5277 2 infusion infusion NN cord-006870-f5w6fw6q 5277 3 , , , cord-006870-f5w6fw6q 5277 4 as as IN cord-006870-f5w6fw6q 5277 5 a a DT cord-006870-f5w6fw6q 5277 6 second second JJ cord-006870-f5w6fw6q 5277 7 line line NN cord-006870-f5w6fw6q 5277 8 sedative sedative NN cord-006870-f5w6fw6q 5277 9 , , , cord-006870-f5w6fw6q 5277 10 had have VBD cord-006870-f5w6fw6q 5277 11 no no DT cord-006870-f5w6fw6q 5277 12 effect effect NN cord-006870-f5w6fw6q 5277 13 on on IN cord-006870-f5w6fw6q 5277 14 mortality mortality NN cord-006870-f5w6fw6q 5277 15 or or CC cord-006870-f5w6fw6q 5277 16 ICP ICP NNP cord-006870-f5w6fw6q 5277 17 , , , cord-006870-f5w6fw6q 5277 18 and and CC cord-006870-f5w6fw6q 5277 19 improved improve VBD cord-006870-f5w6fw6q 5277 20 MAP MAP NNP cord-006870-f5w6fw6q 5277 21 . . . cord-006870-f5w6fw6q 5278 1 However however RB cord-006870-f5w6fw6q 5278 2 , , , cord-006870-f5w6fw6q 5278 3 there there EX cord-006870-f5w6fw6q 5278 4 was be VBD cord-006870-f5w6fw6q 5278 5 a a DT cord-006870-f5w6fw6q 5278 6 nonsignificant nonsignificant JJ cord-006870-f5w6fw6q 5278 7 increase increase NN cord-006870-f5w6fw6q 5278 8 in in IN cord-006870-f5w6fw6q 5278 9 DCI DCI NNP cord-006870-f5w6fw6q 5278 10 as as RB cord-006870-f5w6fw6q 5278 11 well well RB cord-006870-f5w6fw6q 5278 12 as as IN cord-006870-f5w6fw6q 5278 13 vent vent NNP cord-006870-f5w6fw6q 5278 14 LOS LOS NNP cord-006870-f5w6fw6q 5278 15 , , , cord-006870-f5w6fw6q 5278 16 without without IN cord-006870-f5w6fw6q 5278 17 a a DT cord-006870-f5w6fw6q 5278 18 greater great JJR cord-006870-f5w6fw6q 5278 19 rate rate NN cord-006870-f5w6fw6q 5278 20 of of IN cord-006870-f5w6fw6q 5278 21 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 5278 22 . . . cord-006870-f5w6fw6q 5279 1 Prospective prospective JJ cord-006870-f5w6fw6q 5279 2 studies study NNS cord-006870-f5w6fw6q 5279 3 are be VBP cord-006870-f5w6fw6q 5279 4 needed need VBN cord-006870-f5w6fw6q 5279 5 to to TO cord-006870-f5w6fw6q 5279 6 study study VB cord-006870-f5w6fw6q 5279 7 the the DT cord-006870-f5w6fw6q 5279 8 effect effect NN cord-006870-f5w6fw6q 5279 9 on on IN cord-006870-f5w6fw6q 5279 10 DCI DCI NNP cord-006870-f5w6fw6q 5279 11 and and CC cord-006870-f5w6fw6q 5279 12 long long JJ cord-006870-f5w6fw6q 5279 13 term term NN cord-006870-f5w6fw6q 5279 14 outcomes outcome NNS cord-006870-f5w6fw6q 5279 15 . . . cord-006870-f5w6fw6q 5280 1 Seizures seizure NNS cord-006870-f5w6fw6q 5280 2 are be VBP cord-006870-f5w6fw6q 5280 3 a a DT cord-006870-f5w6fw6q 5280 4 well well RB cord-006870-f5w6fw6q 5280 5 - - HYPH cord-006870-f5w6fw6q 5280 6 known know VBN cord-006870-f5w6fw6q 5280 7 complication complication NN cord-006870-f5w6fw6q 5280 8 of of IN cord-006870-f5w6fw6q 5280 9 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5280 10 subarachnoid subarachnoid NNP cord-006870-f5w6fw6q 5280 11 hemorrhage(aSAH hemorrhage(aSAH NNP cord-006870-f5w6fw6q 5280 12 ) ) -RRB- cord-006870-f5w6fw6q 5280 13 and and CC cord-006870-f5w6fw6q 5280 14 occur occur VBP cord-006870-f5w6fw6q 5280 15 most most RBS cord-006870-f5w6fw6q 5280 16 commonly commonly RB cord-006870-f5w6fw6q 5280 17 in in IN cord-006870-f5w6fw6q 5280 18 the the DT cord-006870-f5w6fw6q 5280 19 immediate immediate JJ cord-006870-f5w6fw6q 5280 20 post post JJ cord-006870-f5w6fw6q 5280 21 - - JJ cord-006870-f5w6fw6q 5280 22 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 5280 23 period period NN cord-006870-f5w6fw6q 5280 24 . . . cord-006870-f5w6fw6q 5281 1 Most most RBS cord-006870-f5w6fw6q 5281 2 commonly commonly RB cord-006870-f5w6fw6q 5281 3 used use VBN cord-006870-f5w6fw6q 5281 4 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 5281 5 drugs drug NNS cord-006870-f5w6fw6q 5281 6 ( ( -LRB- cord-006870-f5w6fw6q 5281 7 AEDs AEDs NNP cord-006870-f5w6fw6q 5281 8 ) ) -RRB- cord-006870-f5w6fw6q 5281 9 for for IN cord-006870-f5w6fw6q 5281 10 seizure seizure NN cord-006870-f5w6fw6q 5281 11 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 5281 12 in in IN cord-006870-f5w6fw6q 5281 13 aSAH asah JJ cord-006870-f5w6fw6q 5281 14 include include VBP cord-006870-f5w6fw6q 5281 15 phenytoin phenytoin NN cord-006870-f5w6fw6q 5281 16 and and CC cord-006870-f5w6fw6q 5281 17 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 5281 18 . . . cord-006870-f5w6fw6q 5282 1 There there EX cord-006870-f5w6fw6q 5282 2 is be VBZ cord-006870-f5w6fw6q 5282 3 no no DT cord-006870-f5w6fw6q 5282 4 reliable reliable JJ cord-006870-f5w6fw6q 5282 5 data datum NNS cord-006870-f5w6fw6q 5282 6 available available JJ cord-006870-f5w6fw6q 5282 7 on on IN cord-006870-f5w6fw6q 5282 8 the the DT cord-006870-f5w6fw6q 5282 9 safety safety NN cord-006870-f5w6fw6q 5282 10 and and CC cord-006870-f5w6fw6q 5282 11 efficacy efficacy NN cord-006870-f5w6fw6q 5282 12 of of IN cord-006870-f5w6fw6q 5282 13 restricting restrict VBG cord-006870-f5w6fw6q 5282 14 AED AED NNP cord-006870-f5w6fw6q 5282 15 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 5282 16 only only RB cord-006870-f5w6fw6q 5282 17 till till IN cord-006870-f5w6fw6q 5282 18 the the DT cord-006870-f5w6fw6q 5282 19 aneurysm aneurysm NN cord-006870-f5w6fw6q 5282 20 is be VBZ cord-006870-f5w6fw6q 5282 21 secured secure VBN cord-006870-f5w6fw6q 5282 22 . . . cord-006870-f5w6fw6q 5283 1 We -PRON- PRP cord-006870-f5w6fw6q 5283 2 retrospectively retrospectively RB cord-006870-f5w6fw6q 5283 3 chart chart VBP cord-006870-f5w6fw6q 5283 4 reviewed review VBD cord-006870-f5w6fw6q 5283 5 patients patient NNS cord-006870-f5w6fw6q 5283 6 admitted admit VBN cord-006870-f5w6fw6q 5283 7 to to IN cord-006870-f5w6fw6q 5283 8 our -PRON- PRP$ cord-006870-f5w6fw6q 5283 9 neurosciences neuroscience NNS cord-006870-f5w6fw6q 5283 10 intensive intensive JJ cord-006870-f5w6fw6q 5283 11 - - HYPH cord-006870-f5w6fw6q 5283 12 care care NN cord-006870-f5w6fw6q 5283 13 - - HYPH cord-006870-f5w6fw6q 5283 14 unit unit NN cord-006870-f5w6fw6q 5283 15 with with IN cord-006870-f5w6fw6q 5283 16 aSAH asah JJ cord-006870-f5w6fw6q 5283 17 during during IN cord-006870-f5w6fw6q 5283 18 the the DT cord-006870-f5w6fw6q 5283 19 last last JJ cord-006870-f5w6fw6q 5283 20 two two CD cord-006870-f5w6fw6q 5283 21 years year NNS cord-006870-f5w6fw6q 5283 22 . . . cord-006870-f5w6fw6q 5284 1 Seizure seizure NN cord-006870-f5w6fw6q 5284 2 incidence incidence NN cord-006870-f5w6fw6q 5284 3 was be VBD cord-006870-f5w6fw6q 5284 4 studied study VBN cord-006870-f5w6fw6q 5284 5 in in IN cord-006870-f5w6fw6q 5284 6 patients patient NNS cord-006870-f5w6fw6q 5284 7 treated treat VBN cord-006870-f5w6fw6q 5284 8 with with IN cord-006870-f5w6fw6q 5284 9 phenytoin phenytoin NN cord-006870-f5w6fw6q 5284 10 versus versus IN cord-006870-f5w6fw6q 5284 11 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 5284 12 and and CC cord-006870-f5w6fw6q 5284 13 in in IN cord-006870-f5w6fw6q 5284 14 patients patient NNS cord-006870-f5w6fw6q 5284 15 treated treat VBN cord-006870-f5w6fw6q 5284 16 for for IN cord-006870-f5w6fw6q 5284 17 3 3 CD cord-006870-f5w6fw6q 5284 18 to to TO cord-006870-f5w6fw6q 5284 19 7 7 CD cord-006870-f5w6fw6q 5284 20 days day NNS cord-006870-f5w6fw6q 5284 21 versus versus IN cord-006870-f5w6fw6q 5284 22 those those DT cord-006870-f5w6fw6q 5284 23 where where WRB cord-006870-f5w6fw6q 5284 24 AED AED NNP cord-006870-f5w6fw6q 5284 25 was be VBD cord-006870-f5w6fw6q 5284 26 discontinued discontinue VBN cord-006870-f5w6fw6q 5284 27 immediately immediately RB cord-006870-f5w6fw6q 5284 28 after after IN cord-006870-f5w6fw6q 5284 29 aneurysm aneurysm NN cord-006870-f5w6fw6q 5284 30 was be VBD cord-006870-f5w6fw6q 5284 31 secured secure VBN cord-006870-f5w6fw6q 5284 32 . . . cord-006870-f5w6fw6q 5285 1 In in IN cord-006870-f5w6fw6q 5285 2 28 28 CD cord-006870-f5w6fw6q 5285 3 patients patient NNS cord-006870-f5w6fw6q 5285 4 AED AED NNP cord-006870-f5w6fw6q 5285 5 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 5285 6 was be VBD cord-006870-f5w6fw6q 5285 7 discontinued discontinue VBN cord-006870-f5w6fw6q 5285 8 immediately immediately RB cord-006870-f5w6fw6q 5285 9 after after IN cord-006870-f5w6fw6q 5285 10 the the DT cord-006870-f5w6fw6q 5285 11 aneurysm aneurysm NN cord-006870-f5w6fw6q 5285 12 was be VBD cord-006870-f5w6fw6q 5285 13 secured secure VBN cord-006870-f5w6fw6q 5285 14 , , , cord-006870-f5w6fw6q 5285 15 and and CC cord-006870-f5w6fw6q 5285 16 in in IN cord-006870-f5w6fw6q 5285 17 21 21 CD cord-006870-f5w6fw6q 5285 18 patients patient NNS cord-006870-f5w6fw6q 5285 19 it -PRON- PRP cord-006870-f5w6fw6q 5285 20 was be VBD cord-006870-f5w6fw6q 5285 21 continued continue VBN cord-006870-f5w6fw6q 5285 22 for for IN cord-006870-f5w6fw6q 5285 23 3 3 CD cord-006870-f5w6fw6q 5285 24 to to TO cord-006870-f5w6fw6q 5285 25 7 7 CD cord-006870-f5w6fw6q 5285 26 days day NNS cord-006870-f5w6fw6q 5285 27 . . . cord-006870-f5w6fw6q 5286 1 Of of IN cord-006870-f5w6fw6q 5286 2 th th XX cord-006870-f5w6fw6q 5286 3 phenytoin phenytoin NN cord-006870-f5w6fw6q 5286 4 was be VBD cord-006870-f5w6fw6q 5286 5 used use VBN cord-006870-f5w6fw6q 5286 6 in in IN cord-006870-f5w6fw6q 5286 7 20 20 CD cord-006870-f5w6fw6q 5286 8 patients patient NNS cord-006870-f5w6fw6q 5286 9 and and CC cord-006870-f5w6fw6q 5286 10 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 5286 11 was be VBD cord-006870-f5w6fw6q 5286 12 used use VBN cord-006870-f5w6fw6q 5286 13 in in IN cord-006870-f5w6fw6q 5286 14 8 8 CD cord-006870-f5w6fw6q 5286 15 patients patient NNS cord-006870-f5w6fw6q 5286 16 . . . cord-006870-f5w6fw6q 5287 1 In in IN cord-006870-f5w6fw6q 5287 2 patients patient NNS cord-006870-f5w6fw6q 5287 3 receiving receive VBG cord-006870-f5w6fw6q 5287 4 AED AED NNP cord-006870-f5w6fw6q 5287 5 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 5287 6 for for IN cord-006870-f5w6fw6q 5287 7 3 3 CD cord-006870-f5w6fw6q 5287 8 to to TO cord-006870-f5w6fw6q 5287 9 7 7 CD cord-006870-f5w6fw6q 5287 10 days day NNS cord-006870-f5w6fw6q 5287 11 , , , cord-006870-f5w6fw6q 5287 12 phenytoin phenytoin NNP cord-006870-f5w6fw6q 5287 13 was be VBD cord-006870-f5w6fw6q 5287 14 used use VBN cord-006870-f5w6fw6q 5287 15 in in IN cord-006870-f5w6fw6q 5287 16 8 8 CD cord-006870-f5w6fw6q 5287 17 cases case NNS cord-006870-f5w6fw6q 5287 18 and and CC cord-006870-f5w6fw6q 5287 19 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 5287 20 was be VBD cord-006870-f5w6fw6q 5287 21 used use VBN cord-006870-f5w6fw6q 5287 22 in in IN cord-006870-f5w6fw6q 5287 23 13 13 CD cord-006870-f5w6fw6q 5287 24 cases case NNS cord-006870-f5w6fw6q 5287 25 . . . cord-006870-f5w6fw6q 5288 1 None none NN cord-006870-f5w6fw6q 5288 2 of of IN cord-006870-f5w6fw6q 5288 3 these these DT cord-006870-f5w6fw6q 5288 4 patients patient NNS cord-006870-f5w6fw6q 5288 5 had have VBD cord-006870-f5w6fw6q 5288 6 seizures seizure NNS cord-006870-f5w6fw6q 5288 7 reported report VBN cord-006870-f5w6fw6q 5288 8 during during IN cord-006870-f5w6fw6q 5288 9 hospitalization hospitalization NN cord-006870-f5w6fw6q 5288 10 or or CC cord-006870-f5w6fw6q 5288 11 at at IN cord-006870-f5w6fw6q 5288 12 three three CD cord-006870-f5w6fw6q 5288 13 month month NN cord-006870-f5w6fw6q 5288 14 follow follow NN cord-006870-f5w6fw6q 5288 15 - - HYPH cord-006870-f5w6fw6q 5288 16 up up NN cord-006870-f5w6fw6q 5288 17 . . . cord-006870-f5w6fw6q 5289 1 Stopping stop VBG cord-006870-f5w6fw6q 5289 2 the the DT cord-006870-f5w6fw6q 5289 3 AED AED NNP cord-006870-f5w6fw6q 5289 4 prophylaxis prophylaxis NN cord-006870-f5w6fw6q 5289 5 immediately immediately RB cord-006870-f5w6fw6q 5289 6 after after IN cord-006870-f5w6fw6q 5289 7 aneurysm aneurysm NN cord-006870-f5w6fw6q 5289 8 coiling coiling NN cord-006870-f5w6fw6q 5289 9 is be VBZ cord-006870-f5w6fw6q 5289 10 not not RB cord-006870-f5w6fw6q 5289 11 associated associate VBN cord-006870-f5w6fw6q 5289 12 with with IN cord-006870-f5w6fw6q 5289 13 increased increase VBN cord-006870-f5w6fw6q 5289 14 risk risk NN cord-006870-f5w6fw6q 5289 15 of of IN cord-006870-f5w6fw6q 5289 16 seizures seizure NNS cord-006870-f5w6fw6q 5289 17 . . . cord-006870-f5w6fw6q 5290 1 Seizures seizure NNS cord-006870-f5w6fw6q 5290 2 at at IN cord-006870-f5w6fw6q 5290 3 presentation presentation NN cord-006870-f5w6fw6q 5290 4 in in IN cord-006870-f5w6fw6q 5290 5 patients patient NNS cord-006870-f5w6fw6q 5290 6 with with IN cord-006870-f5w6fw6q 5290 7 aSAH asah JJ cord-006870-f5w6fw6q 5290 8 are be VBP cord-006870-f5w6fw6q 5290 9 not not RB cord-006870-f5w6fw6q 5290 10 associated associate VBN cord-006870-f5w6fw6q 5290 11 with with IN cord-006870-f5w6fw6q 5290 12 development development NN cord-006870-f5w6fw6q 5290 13 of of IN cord-006870-f5w6fw6q 5290 14 epilepsy epilepsy NN cord-006870-f5w6fw6q 5290 15 at at IN cord-006870-f5w6fw6q 5290 16 3 3 CD cord-006870-f5w6fw6q 5290 17 months month NNS cord-006870-f5w6fw6q 5290 18 . . . cord-006870-f5w6fw6q 5291 1 Both both DT cord-006870-f5w6fw6q 5291 2 phenytoin phenytoin NN cord-006870-f5w6fw6q 5291 3 and and CC cord-006870-f5w6fw6q 5291 4 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 5291 5 are be VBP cord-006870-f5w6fw6q 5291 6 well well RB cord-006870-f5w6fw6q 5291 7 tolerated tolerate VBN cord-006870-f5w6fw6q 5291 8 in in IN cord-006870-f5w6fw6q 5291 9 patients patient NNS cord-006870-f5w6fw6q 5291 10 with with IN cord-006870-f5w6fw6q 5291 11 aSAH asah JJ cord-006870-f5w6fw6q 5291 12 when when WRB cord-006870-f5w6fw6q 5291 13 limited limit VBN cord-006870-f5w6fw6q 5291 14 to to IN cord-006870-f5w6fw6q 5291 15 the the DT cord-006870-f5w6fw6q 5291 16 immediate immediate JJ cord-006870-f5w6fw6q 5291 17 post post JJ cord-006870-f5w6fw6q 5291 18 - - JJ cord-006870-f5w6fw6q 5291 19 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 5291 20 period period NN cord-006870-f5w6fw6q 5291 21 . . . cord-006870-f5w6fw6q 5292 1 The the DT cord-006870-f5w6fw6q 5292 2 main main JJ cord-006870-f5w6fw6q 5292 3 preceding precede VBG cord-006870-f5w6fw6q 5292 4 factor factor NN cord-006870-f5w6fw6q 5292 5 of of IN cord-006870-f5w6fw6q 5292 6 Delayed delay VBN cord-006870-f5w6fw6q 5292 7 cerebral cerebral JJ cord-006870-f5w6fw6q 5292 8 ischemia ischemia NN cord-006870-f5w6fw6q 5292 9 ( ( -LRB- cord-006870-f5w6fw6q 5292 10 DCI DCI NNP cord-006870-f5w6fw6q 5292 11 ) ) -RRB- cord-006870-f5w6fw6q 5292 12 in in IN cord-006870-f5w6fw6q 5292 13 aSAH asah JJ cord-006870-f5w6fw6q 5292 14 is be VBZ cord-006870-f5w6fw6q 5292 15 cerebral cerebral JJ cord-006870-f5w6fw6q 5292 16 vasospasm vasospasm NN cord-006870-f5w6fw6q 5292 17 ( ( -LRB- cord-006870-f5w6fw6q 5292 18 CVS CVS NNP cord-006870-f5w6fw6q 5292 19 ) ) -RRB- cord-006870-f5w6fw6q 5292 20 . . . cord-006870-f5w6fw6q 5293 1 Anticipating anticipate VBG cord-006870-f5w6fw6q 5293 2 DCI DCI NNP cord-006870-f5w6fw6q 5293 3 can can MD cord-006870-f5w6fw6q 5293 4 have have VB cord-006870-f5w6fw6q 5293 5 major major JJ cord-006870-f5w6fw6q 5293 6 impact impact NN cord-006870-f5w6fw6q 5293 7 on on IN cord-006870-f5w6fw6q 5293 8 patient patient JJ cord-006870-f5w6fw6q 5293 9 outcomes outcome NNS cord-006870-f5w6fw6q 5293 10 . . . cord-006870-f5w6fw6q 5294 1 Studies study NNS cord-006870-f5w6fw6q 5294 2 have have VBP cord-006870-f5w6fw6q 5294 3 attempted attempt VBN cord-006870-f5w6fw6q 5294 4 to to TO cord-006870-f5w6fw6q 5294 5 predict predict VB cord-006870-f5w6fw6q 5294 6 DCI DCI NNP cord-006870-f5w6fw6q 5294 7 in in IN cord-006870-f5w6fw6q 5294 8 patients patient NNS cord-006870-f5w6fw6q 5294 9 with with IN cord-006870-f5w6fw6q 5294 10 aSAH asah JJ cord-006870-f5w6fw6q 5294 11 by by IN cord-006870-f5w6fw6q 5294 12 using use VBG cord-006870-f5w6fw6q 5294 13 various various JJ cord-006870-f5w6fw6q 5294 14 imaging imaging NN cord-006870-f5w6fw6q 5294 15 modalities modality NNS cord-006870-f5w6fw6q 5294 16 that that WDT cord-006870-f5w6fw6q 5294 17 measure measure VBP cord-006870-f5w6fw6q 5294 18 CVS CVS NNP cord-006870-f5w6fw6q 5294 19 , , , cord-006870-f5w6fw6q 5294 20 ranging range VBG cord-006870-f5w6fw6q 5294 21 from from IN cord-006870-f5w6fw6q 5294 22 transcranial transcranial JJ cord-006870-f5w6fw6q 5294 23 Doppler Doppler NNP cord-006870-f5w6fw6q 5294 24 ultrasonography ultrasonography NN cord-006870-f5w6fw6q 5294 25 , , , cord-006870-f5w6fw6q 5294 26 CTP CTP NNP cord-006870-f5w6fw6q 5294 27 , , , cord-006870-f5w6fw6q 5294 28 and and CC cord-006870-f5w6fw6q 5294 29 MR MR NNP cord-006870-f5w6fw6q 5294 30 perfusion perfusion NN cord-006870-f5w6fw6q 5294 31 . . . cord-006870-f5w6fw6q 5295 1 Few few JJ cord-006870-f5w6fw6q 5295 2 compare compare VBP cord-006870-f5w6fw6q 5295 3 these these DT cord-006870-f5w6fw6q 5295 4 imaging image VBG cord-006870-f5w6fw6q 5295 5 modalities modality NNS cord-006870-f5w6fw6q 5295 6 to to IN cord-006870-f5w6fw6q 5295 7 the the DT cord-006870-f5w6fw6q 5295 8 accepted accept VBN cord-006870-f5w6fw6q 5295 9 gold gold NN cord-006870-f5w6fw6q 5295 10 standard standard NN cord-006870-f5w6fw6q 5295 11 of of IN cord-006870-f5w6fw6q 5295 12 DSA DSA NNP cord-006870-f5w6fw6q 5295 13 . . . cord-006870-f5w6fw6q 5296 1 We -PRON- PRP cord-006870-f5w6fw6q 5296 2 propose propose VBP cord-006870-f5w6fw6q 5296 3 that that IN cord-006870-f5w6fw6q 5296 4 MRI MRI NNP cord-006870-f5w6fw6q 5296 5 using use VBG cord-006870-f5w6fw6q 5296 6 ASL ASL NNP cord-006870-f5w6fw6q 5296 7 imaging imaging NN cord-006870-f5w6fw6q 5296 8 can can MD cord-006870-f5w6fw6q 5296 9 be be VB cord-006870-f5w6fw6q 5296 10 used use VBN cord-006870-f5w6fw6q 5296 11 as as IN cord-006870-f5w6fw6q 5296 12 a a DT cord-006870-f5w6fw6q 5296 13 sensitive sensitive JJ cord-006870-f5w6fw6q 5296 14 and and CC cord-006870-f5w6fw6q 5296 15 specific specific JJ cord-006870-f5w6fw6q 5296 16 measure measure NN cord-006870-f5w6fw6q 5296 17 of of IN cord-006870-f5w6fw6q 5296 18 CVS cvs NN cord-006870-f5w6fw6q 5296 19 and and CC cord-006870-f5w6fw6q 5296 20 can can MD cord-006870-f5w6fw6q 5296 21 be be VB cord-006870-f5w6fw6q 5296 22 used use VBN cord-006870-f5w6fw6q 5296 23 as as IN cord-006870-f5w6fw6q 5296 24 a a DT cord-006870-f5w6fw6q 5296 25 marker marker NN cord-006870-f5w6fw6q 5296 26 to to TO cord-006870-f5w6fw6q 5296 27 identify identify VB cord-006870-f5w6fw6q 5296 28 patients patient NNS cord-006870-f5w6fw6q 5296 29 with with IN cord-006870-f5w6fw6q 5296 30 aSAH asah JJ cord-006870-f5w6fw6q 5296 31 who who WP cord-006870-f5w6fw6q 5296 32 are be VBP cord-006870-f5w6fw6q 5296 33 at at IN cord-006870-f5w6fw6q 5296 34 risk risk NN cord-006870-f5w6fw6q 5296 35 for for IN cord-006870-f5w6fw6q 5296 36 developing develop VBG cord-006870-f5w6fw6q 5296 37 DCI DCI NNP cord-006870-f5w6fw6q 5296 38 . . . cord-006870-f5w6fw6q 5297 1 To to TO cord-006870-f5w6fw6q 5297 2 support support VB cord-006870-f5w6fw6q 5297 3 our -PRON- PRP$ cord-006870-f5w6fw6q 5297 4 hypothesis hypothesis NN cord-006870-f5w6fw6q 5297 5 , , , cord-006870-f5w6fw6q 5297 6 we -PRON- PRP cord-006870-f5w6fw6q 5297 7 compare compare VBP cord-006870-f5w6fw6q 5297 8 ASL ASL NNP cord-006870-f5w6fw6q 5297 9 results result NNS cord-006870-f5w6fw6q 5297 10 in in IN cord-006870-f5w6fw6q 5297 11 patients patient NNS cord-006870-f5w6fw6q 5297 12 with with IN cord-006870-f5w6fw6q 5297 13 documented document VBN cord-006870-f5w6fw6q 5297 14 CVS CVS NNP cord-006870-f5w6fw6q 5297 15 on on IN cord-006870-f5w6fw6q 5297 16 DSA DSA NNP cord-006870-f5w6fw6q 5297 17 who who WP cord-006870-f5w6fw6q 5297 18 developed develop VBD cord-006870-f5w6fw6q 5297 19 DCI DCI NNP cord-006870-f5w6fw6q 5297 20 . . . cord-006870-f5w6fw6q 5298 1 165 165 CD cord-006870-f5w6fw6q 5298 2 patients patient NNS cord-006870-f5w6fw6q 5298 3 in in IN cord-006870-f5w6fw6q 5298 4 the the DT cord-006870-f5w6fw6q 5298 5 academic academic JJ cord-006870-f5w6fw6q 5298 6 years year NNS cord-006870-f5w6fw6q 5298 7 2013 2013 CD cord-006870-f5w6fw6q 5298 8 to to IN cord-006870-f5w6fw6q 5298 9 2016 2016 CD cord-006870-f5w6fw6q 5298 10 with with IN cord-006870-f5w6fw6q 5298 11 the the DT cord-006870-f5w6fw6q 5298 12 diagnosis diagnosis NN cord-006870-f5w6fw6q 5298 13 of of IN cord-006870-f5w6fw6q 5298 14 aSAH asah JJ cord-006870-f5w6fw6q 5298 15 were be VBD cord-006870-f5w6fw6q 5298 16 admitted admit VBN cord-006870-f5w6fw6q 5298 17 to to IN cord-006870-f5w6fw6q 5298 18 our -PRON- PRP$ cord-006870-f5w6fw6q 5298 19 NICU NICU NNP cord-006870-f5w6fw6q 5298 20 . . . cord-006870-f5w6fw6q 5299 1 The the DT cord-006870-f5w6fw6q 5299 2 inclusion inclusion NN cord-006870-f5w6fw6q 5299 3 criteria criterion NNS cord-006870-f5w6fw6q 5299 4 for for IN cord-006870-f5w6fw6q 5299 5 the the DT cord-006870-f5w6fw6q 5299 6 patient patient JJ cord-006870-f5w6fw6q 5299 7 population population NN cord-006870-f5w6fw6q 5299 8 was be VBD cord-006870-f5w6fw6q 5299 9 the the DT cord-006870-f5w6fw6q 5299 10 presence presence NN cord-006870-f5w6fw6q 5299 11 of of IN cord-006870-f5w6fw6q 5299 12 aSAH aSAH NNP cord-006870-f5w6fw6q 5299 13 confirmed confirm VBN cord-006870-f5w6fw6q 5299 14 by by IN cord-006870-f5w6fw6q 5299 15 DSA DSA NNP cord-006870-f5w6fw6q 5299 16 , , , cord-006870-f5w6fw6q 5299 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 5299 18 of of IN cord-006870-f5w6fw6q 5299 19 DCI DCI NNP cord-006870-f5w6fw6q 5299 20 by by IN cord-006870-f5w6fw6q 5299 21 a a DT cord-006870-f5w6fw6q 5299 22 neurointensivist neurointensivist NN cord-006870-f5w6fw6q 5299 23 , , , cord-006870-f5w6fw6q 5299 24 MRI MRI NNP cord-006870-f5w6fw6q 5299 25 with with IN cord-006870-f5w6fw6q 5299 26 ASL ASL NNP cord-006870-f5w6fw6q 5299 27 , , , cord-006870-f5w6fw6q 5299 28 and and CC cord-006870-f5w6fw6q 5299 29 a a DT cord-006870-f5w6fw6q 5299 30 repeated repeat VBN cord-006870-f5w6fw6q 5299 31 DSA DSA NNP cord-006870-f5w6fw6q 5299 32 during during IN cord-006870-f5w6fw6q 5299 33 the the DT cord-006870-f5w6fw6q 5299 34 hospitalization hospitalization NN cord-006870-f5w6fw6q 5299 35 after after IN cord-006870-f5w6fw6q 5299 36 DCI DCI NNP cord-006870-f5w6fw6q 5299 37 was be VBD cord-006870-f5w6fw6q 5299 38 suspected suspect VBN cord-006870-f5w6fw6q 5299 39 . . . cord-006870-f5w6fw6q 5300 1 All all DT cord-006870-f5w6fw6q 5300 2 patients patient NNS cord-006870-f5w6fw6q 5300 3 underwent undergo VBD cord-006870-f5w6fw6q 5300 4 MRA MRA NNP cord-006870-f5w6fw6q 5300 5 with with IN cord-006870-f5w6fw6q 5300 6 ASL ASL NNP cord-006870-f5w6fw6q 5300 7 on on IN cord-006870-f5w6fw6q 5300 8 Day Day NNP cord-006870-f5w6fw6q 5300 9 8 8 CD cord-006870-f5w6fw6q 5300 10 in in IN cord-006870-f5w6fw6q 5300 11 an an DT cord-006870-f5w6fw6q 5300 12 attempt attempt NN cord-006870-f5w6fw6q 5300 13 to to TO cord-006870-f5w6fw6q 5300 14 capture capture VB cord-006870-f5w6fw6q 5300 15 the the DT cord-006870-f5w6fw6q 5300 16 peak peak NN cord-006870-f5w6fw6q 5300 17 time time NN cord-006870-f5w6fw6q 5300 18 of of IN cord-006870-f5w6fw6q 5300 19 CVS CVS NNP cord-006870-f5w6fw6q 5300 20 . . . cord-006870-f5w6fw6q 5301 1 Nine nine CD cord-006870-f5w6fw6q 5301 2 patients patient NNS cord-006870-f5w6fw6q 5301 3 were be VBD cord-006870-f5w6fw6q 5301 4 included include VBN cord-006870-f5w6fw6q 5301 5 in in IN cord-006870-f5w6fw6q 5301 6 this this DT cord-006870-f5w6fw6q 5301 7 study study NN cord-006870-f5w6fw6q 5301 8 . . . cord-006870-f5w6fw6q 5302 1 All all DT cord-006870-f5w6fw6q 5302 2 cases case NNS cord-006870-f5w6fw6q 5302 3 with with IN cord-006870-f5w6fw6q 5302 4 perfusion perfusion NN cord-006870-f5w6fw6q 5302 5 defects defect NNS cord-006870-f5w6fw6q 5302 6 on on IN cord-006870-f5w6fw6q 5302 7 ASL ASL NNP cord-006870-f5w6fw6q 5302 8 sequences sequence NNS cord-006870-f5w6fw6q 5302 9 had have VBD cord-006870-f5w6fw6q 5302 10 confirmed confirm VBN cord-006870-f5w6fw6q 5302 11 CVS CVS NNP cord-006870-f5w6fw6q 5302 12 on on IN cord-006870-f5w6fw6q 5302 13 DSA DSA NNP cord-006870-f5w6fw6q 5302 14 except except IN cord-006870-f5w6fw6q 5302 15 for for IN cord-006870-f5w6fw6q 5302 16 one one CD cord-006870-f5w6fw6q 5302 17 . . . cord-006870-f5w6fw6q 5303 1 The the DT cord-006870-f5w6fw6q 5303 2 outlier outlier NN cord-006870-f5w6fw6q 5303 3 in in IN cord-006870-f5w6fw6q 5303 4 our -PRON- PRP$ cord-006870-f5w6fw6q 5303 5 cohort cohort NN cord-006870-f5w6fw6q 5303 6 developed develop VBD cord-006870-f5w6fw6q 5303 7 DCI DCI NNP cord-006870-f5w6fw6q 5303 8 with with IN cord-006870-f5w6fw6q 5303 9 asymmetry asymmetry NN cord-006870-f5w6fw6q 5303 10 on on IN cord-006870-f5w6fw6q 5303 11 ASL ASL NNP cord-006870-f5w6fw6q 5303 12 that that WDT cord-006870-f5w6fw6q 5303 13 was be VBD cord-006870-f5w6fw6q 5303 14 not not RB cord-006870-f5w6fw6q 5303 15 demonstrated demonstrate VBN cord-006870-f5w6fw6q 5303 16 on on IN cord-006870-f5w6fw6q 5303 17 DSA DSA NNP cord-006870-f5w6fw6q 5303 18 . . . cord-006870-f5w6fw6q 5304 1 To to IN cord-006870-f5w6fw6q 5304 2 our -PRON- PRP$ cord-006870-f5w6fw6q 5304 3 knowledge knowledge NN cord-006870-f5w6fw6q 5304 4 , , , cord-006870-f5w6fw6q 5304 5 no no DT cord-006870-f5w6fw6q 5304 6 studies study NNS cord-006870-f5w6fw6q 5304 7 have have VBP cord-006870-f5w6fw6q 5304 8 compared compare VBN cord-006870-f5w6fw6q 5304 9 the the DT cord-006870-f5w6fw6q 5304 10 specificity specificity NN cord-006870-f5w6fw6q 5304 11 of of IN cord-006870-f5w6fw6q 5304 12 ASL ASL NNP cord-006870-f5w6fw6q 5304 13 with with IN cord-006870-f5w6fw6q 5304 14 DSA DSA NNP cord-006870-f5w6fw6q 5304 15 in in IN cord-006870-f5w6fw6q 5304 16 detecting detect VBG cord-006870-f5w6fw6q 5304 17 CVS CVS NNP cord-006870-f5w6fw6q 5304 18 . . . cord-006870-f5w6fw6q 5305 1 This this DT cord-006870-f5w6fw6q 5305 2 study study NN cord-006870-f5w6fw6q 5305 3 highlights highlight VBZ cord-006870-f5w6fw6q 5305 4 the the DT cord-006870-f5w6fw6q 5305 5 utility utility NN cord-006870-f5w6fw6q 5305 6 of of IN cord-006870-f5w6fw6q 5305 7 ASL ASL NNP cord-006870-f5w6fw6q 5305 8 in in IN cord-006870-f5w6fw6q 5305 9 detecting detect VBG cord-006870-f5w6fw6q 5305 10 CVS CVS NNP cord-006870-f5w6fw6q 5305 11 in in IN cord-006870-f5w6fw6q 5305 12 patients patient NNS cord-006870-f5w6fw6q 5305 13 with with IN cord-006870-f5w6fw6q 5305 14 aSAH asah JJ cord-006870-f5w6fw6q 5305 15 . . . cord-006870-f5w6fw6q 5306 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5306 2 limited limited JJ cord-006870-f5w6fw6q 5306 3 data datum NNS cord-006870-f5w6fw6q 5306 4 suggests suggest VBZ cord-006870-f5w6fw6q 5306 5 ASL ASL NNP cord-006870-f5w6fw6q 5306 6 can can MD cord-006870-f5w6fw6q 5306 7 be be VB cord-006870-f5w6fw6q 5306 8 utilized utilize VBN cord-006870-f5w6fw6q 5306 9 for for IN cord-006870-f5w6fw6q 5306 10 detection detection NN cord-006870-f5w6fw6q 5306 11 of of IN cord-006870-f5w6fw6q 5306 12 DCI DCI NNP cord-006870-f5w6fw6q 5306 13 and and CC cord-006870-f5w6fw6q 5306 14 CVS CVS NNP cord-006870-f5w6fw6q 5306 15 with with IN cord-006870-f5w6fw6q 5306 16 greater great JJR cord-006870-f5w6fw6q 5306 17 confidence confidence NN cord-006870-f5w6fw6q 5306 18 than than IN cord-006870-f5w6fw6q 5306 19 the the DT cord-006870-f5w6fw6q 5306 20 conventional conventional JJ cord-006870-f5w6fw6q 5306 21 modalities modality NNS cord-006870-f5w6fw6q 5306 22 . . . cord-006870-f5w6fw6q 5307 1 We -PRON- PRP cord-006870-f5w6fw6q 5307 2 also also RB cord-006870-f5w6fw6q 5307 3 suggest suggest VBP cord-006870-f5w6fw6q 5307 4 that that IN cord-006870-f5w6fw6q 5307 5 ASL ASL NNP cord-006870-f5w6fw6q 5307 6 approaches approach VBZ cord-006870-f5w6fw6q 5307 7 the the DT cord-006870-f5w6fw6q 5307 8 utility utility NN cord-006870-f5w6fw6q 5307 9 of of IN cord-006870-f5w6fw6q 5307 10 DSA DSA NNP cord-006870-f5w6fw6q 5307 11 in in IN cord-006870-f5w6fw6q 5307 12 the the DT cord-006870-f5w6fw6q 5307 13 detection detection NN cord-006870-f5w6fw6q 5307 14 of of IN cord-006870-f5w6fw6q 5307 15 CVS CVS NNP cord-006870-f5w6fw6q 5307 16 . . . cord-006870-f5w6fw6q 5308 1 Blood blood NN cord-006870-f5w6fw6q 5308 2 glucose glucose NN cord-006870-f5w6fw6q 5308 3 dysregulation dysregulation NN cord-006870-f5w6fw6q 5308 4 following follow VBG cord-006870-f5w6fw6q 5308 5 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5308 6 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5308 7 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5308 8 is be VBZ cord-006870-f5w6fw6q 5308 9 associated associate VBN cord-006870-f5w6fw6q 5308 10 with with IN cord-006870-f5w6fw6q 5308 11 serious serious JJ cord-006870-f5w6fw6q 5308 12 complications complication NNS cord-006870-f5w6fw6q 5308 13 and and CC cord-006870-f5w6fw6q 5308 14 poor poor JJ cord-006870-f5w6fw6q 5308 15 clinical clinical JJ cord-006870-f5w6fw6q 5308 16 outcome outcome NN cord-006870-f5w6fw6q 5308 17 . . . cord-006870-f5w6fw6q 5309 1 An an DT cord-006870-f5w6fw6q 5309 2 influence influence NN cord-006870-f5w6fw6q 5309 3 of of IN cord-006870-f5w6fw6q 5309 4 hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 5309 5 on on IN cord-006870-f5w6fw6q 5309 6 the the DT cord-006870-f5w6fw6q 5309 7 occurrence occurrence NN cord-006870-f5w6fw6q 5309 8 of of IN cord-006870-f5w6fw6q 5309 9 delayed delay VBN cord-006870-f5w6fw6q 5309 10 cerebral cerebral JJ cord-006870-f5w6fw6q 5309 11 ischemia ischemia NN cord-006870-f5w6fw6q 5309 12 ( ( -LRB- cord-006870-f5w6fw6q 5309 13 DCI DCI NNP cord-006870-f5w6fw6q 5309 14 ) ) -RRB- cord-006870-f5w6fw6q 5309 15 is be VBZ cord-006870-f5w6fw6q 5309 16 assumed assume VBN cord-006870-f5w6fw6q 5309 17 , , , cord-006870-f5w6fw6q 5309 18 nevertheless nevertheless RB cord-006870-f5w6fw6q 5309 19 the the DT cord-006870-f5w6fw6q 5309 20 exact exact JJ cord-006870-f5w6fw6q 5309 21 mechanism mechanism NN cord-006870-f5w6fw6q 5309 22 remains remain VBZ cord-006870-f5w6fw6q 5309 23 unclear unclear JJ cord-006870-f5w6fw6q 5309 24 . . . cord-006870-f5w6fw6q 5310 1 The the DT cord-006870-f5w6fw6q 5310 2 goal goal NN cord-006870-f5w6fw6q 5310 3 of of IN cord-006870-f5w6fw6q 5310 4 the the DT cord-006870-f5w6fw6q 5310 5 present present JJ cord-006870-f5w6fw6q 5310 6 study study NN cord-006870-f5w6fw6q 5310 7 aims aim VBZ cord-006870-f5w6fw6q 5310 8 to to TO cord-006870-f5w6fw6q 5310 9 investigate investigate VB cord-006870-f5w6fw6q 5310 10 the the DT cord-006870-f5w6fw6q 5310 11 influence influence NN cord-006870-f5w6fw6q 5310 12 of of IN cord-006870-f5w6fw6q 5310 13 systemic systemic JJ cord-006870-f5w6fw6q 5310 14 blood blood NN cord-006870-f5w6fw6q 5310 15 glucose glucose NN cord-006870-f5w6fw6q 5310 16 level level NN cord-006870-f5w6fw6q 5310 17 on on IN cord-006870-f5w6fw6q 5310 18 cerebral cerebral JJ cord-006870-f5w6fw6q 5310 19 perfusion perfusion NN cord-006870-f5w6fw6q 5310 20 measured measure VBN cord-006870-f5w6fw6q 5310 21 by by IN cord-006870-f5w6fw6q 5310 22 dynamic dynamic JJ cord-006870-f5w6fw6q 5310 23 perfusion perfusion NN cord-006870-f5w6fw6q 5310 24 computed compute VBN cord-006870-f5w6fw6q 5310 25 tomography tomography NN cord-006870-f5w6fw6q 5310 26 ( ( -LRB- cord-006870-f5w6fw6q 5310 27 PCT PCT NNP cord-006870-f5w6fw6q 5310 28 ) ) -RRB- cord-006870-f5w6fw6q 5310 29 and and CC cord-006870-f5w6fw6q 5310 30 outcome outcome NN cord-006870-f5w6fw6q 5310 31 . . . cord-006870-f5w6fw6q 5311 1 Daily daily JJ cord-006870-f5w6fw6q 5311 2 serial serial JJ cord-006870-f5w6fw6q 5311 3 blood blood NN cord-006870-f5w6fw6q 5311 4 glucose glucose NN cord-006870-f5w6fw6q 5311 5 levels level NNS cord-006870-f5w6fw6q 5311 6 and and CC cord-006870-f5w6fw6q 5311 7 PCT PCT NNP cord-006870-f5w6fw6q 5311 8 data data NN cord-006870-f5w6fw6q 5311 9 sets set NNS cord-006870-f5w6fw6q 5311 10 of of IN cord-006870-f5w6fw6q 5311 11 206 206 CD cord-006870-f5w6fw6q 5311 12 patients patient NNS cord-006870-f5w6fw6q 5311 13 treated treat VBN cord-006870-f5w6fw6q 5311 14 at at IN cord-006870-f5w6fw6q 5311 15 our -PRON- PRP$ cord-006870-f5w6fw6q 5311 16 neurointensive neurointensive NNP cord-006870-f5w6fw6q 5311 17 care care NN cord-006870-f5w6fw6q 5311 18 unit unit NN cord-006870-f5w6fw6q 5311 19 after after IN cord-006870-f5w6fw6q 5311 20 aSAH aSAH NNP cord-006870-f5w6fw6q 5311 21 were be VBD cord-006870-f5w6fw6q 5311 22 retrospectively retrospectively RB cord-006870-f5w6fw6q 5311 23 analyzed analyze VBN cord-006870-f5w6fw6q 5311 24 . . . cord-006870-f5w6fw6q 5312 1 Serial serial JJ cord-006870-f5w6fw6q 5312 2 PCTs pct NNS cord-006870-f5w6fw6q 5312 3 were be VBD cord-006870-f5w6fw6q 5312 4 performed perform VBN cord-006870-f5w6fw6q 5312 5 between between IN cord-006870-f5w6fw6q 5312 6 six six CD cord-006870-f5w6fw6q 5312 7 hours hour NNS cord-006870-f5w6fw6q 5312 8 and and CC cord-006870-f5w6fw6q 5312 9 21 21 CD cord-006870-f5w6fw6q 5312 10 days day NNS cord-006870-f5w6fw6q 5312 11 after after IN cord-006870-f5w6fw6q 5312 12 aneurysm aneurysm NN cord-006870-f5w6fw6q 5312 13 repair repair NN cord-006870-f5w6fw6q 5312 14 . . . cord-006870-f5w6fw6q 5313 1 Mean mean JJ cord-006870-f5w6fw6q 5313 2 average average JJ cord-006870-f5w6fw6q 5313 3 of of IN cord-006870-f5w6fw6q 5313 4 mean mean JJ cord-006870-f5w6fw6q 5313 5 transit transit NN cord-006870-f5w6fw6q 5313 6 times time NNS cord-006870-f5w6fw6q 5313 7 ( ( -LRB- cord-006870-f5w6fw6q 5313 8 MTTs mtt NNS cord-006870-f5w6fw6q 5313 9 ) ) -RRB- cord-006870-f5w6fw6q 5313 10 was be VBD cord-006870-f5w6fw6q 5313 11 calculated calculate VBN cord-006870-f5w6fw6q 5313 12 for for IN cord-006870-f5w6fw6q 5313 13 each each DT cord-006870-f5w6fw6q 5313 14 perfusion perfusion NN cord-006870-f5w6fw6q 5313 15 scan scan NN cord-006870-f5w6fw6q 5313 16 . . . cord-006870-f5w6fw6q 5314 1 The the DT cord-006870-f5w6fw6q 5314 2 maximum maximum JJ cord-006870-f5w6fw6q 5314 3 mean mean NN cord-006870-f5w6fw6q 5314 4 transit transit NN cord-006870-f5w6fw6q 5314 5 time time NN cord-006870-f5w6fw6q 5314 6 ( ( -LRB- cord-006870-f5w6fw6q 5314 7 maxMTT maxMTT NNP cord-006870-f5w6fw6q 5314 8 ) ) -RRB- cord-006870-f5w6fw6q 5314 9 and and CC cord-006870-f5w6fw6q 5314 10 outcome outcome NN cord-006870-f5w6fw6q 5314 11 assessed assess VBN cord-006870-f5w6fw6q 5314 12 with with IN cord-006870-f5w6fw6q 5314 13 Glasgow Glasgow NNP cord-006870-f5w6fw6q 5314 14 Outcome Outcome NNP cord-006870-f5w6fw6q 5314 15 Scale Scale NNP cord-006870-f5w6fw6q 5314 16 were be VBD cord-006870-f5w6fw6q 5314 17 correlated correlate VBN cord-006870-f5w6fw6q 5314 18 with with IN cord-006870-f5w6fw6q 5314 19 defined define VBN cord-006870-f5w6fw6q 5314 20 blood blood NN cord-006870-f5w6fw6q 5314 21 glucose glucose NN cord-006870-f5w6fw6q 5314 22 ranges range NNS cord-006870-f5w6fw6q 5314 23 as as IN cord-006870-f5w6fw6q 5314 24 followed follow VBN cord-006870-f5w6fw6q 5314 25 1 1 CD cord-006870-f5w6fw6q 5314 26 . . . cord-006870-f5w6fw6q 5314 27 ) ) -RRB- cord-006870-f5w6fw6q 5315 1 > > XX cord-006870-f5w6fw6q 5316 1 180mg 180mg NNP cord-006870-f5w6fw6q 5316 2 / / SYM cord-006870-f5w6fw6q 5316 3 dl dl NNP cord-006870-f5w6fw6q 5316 4 ( ( -LRB- cord-006870-f5w6fw6q 5316 5 hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 5316 6 ) ) -RRB- cord-006870-f5w6fw6q 5316 7 2 2 CD cord-006870-f5w6fw6q 5316 8 . . . cord-006870-f5w6fw6q 5316 9 ) ) -RRB- cord-006870-f5w6fw6q 5317 1 140 140 CD cord-006870-f5w6fw6q 5317 2 - - SYM cord-006870-f5w6fw6q 5317 3 180 180 CD cord-006870-f5w6fw6q 5317 4 mg mg NN cord-006870-f5w6fw6q 5318 1 /dl /dl NFP cord-006870-f5w6fw6q 5318 2 ( ( -LRB- cord-006870-f5w6fw6q 5318 3 elevated elevated JJ cord-006870-f5w6fw6q 5318 4 glucose glucose NN cord-006870-f5w6fw6q 5318 5 level level NN cord-006870-f5w6fw6q 5318 6 ) ) -RRB- cord-006870-f5w6fw6q 5318 7 3 3 CD cord-006870-f5w6fw6q 5318 8 . . . cord-006870-f5w6fw6q 5318 9 ) ) -RRB- cord-006870-f5w6fw6q 5319 1 110 110 CD cord-006870-f5w6fw6q 5319 2 - - HYPH cord-006870-f5w6fw6q 5319 3 140mg 140mg NNP cord-006870-f5w6fw6q 5319 4 / / SYM cord-006870-f5w6fw6q 5319 5 dl dl NN cord-006870-f5w6fw6q 5319 6 ( ( -LRB- cord-006870-f5w6fw6q 5319 7 strict strict JJ cord-006870-f5w6fw6q 5319 8 glucose glucose NN cord-006870-f5w6fw6q 5319 9 control control NN cord-006870-f5w6fw6q 5319 10 ) ) -RRB- cord-006870-f5w6fw6q 5319 11 and and CC cord-006870-f5w6fw6q 5319 12 < < NNP cord-006870-f5w6fw6q 5319 13 110mg 110mg NNP cord-006870-f5w6fw6q 5319 14 / / SYM cord-006870-f5w6fw6q 5319 15 dl dl NNP cord-006870-f5w6fw6q 5319 16 ( ( -LRB- cord-006870-f5w6fw6q 5319 17 low low JJ cord-006870-f5w6fw6q 5319 18 glucose glucose NN cord-006870-f5w6fw6q 5319 19 level level NN cord-006870-f5w6fw6q 5319 20 ) ) -RRB- cord-006870-f5w6fw6q 5319 21 . . . cord-006870-f5w6fw6q 5320 1 Hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 5320 2 ( ( -LRB- cord-006870-f5w6fw6q 5320 3 > > NFP cord-006870-f5w6fw6q 5320 4 180 180 CD cord-006870-f5w6fw6q 5320 5 mg mg NNP cord-006870-f5w6fw6q 5320 6 / / SYM cord-006870-f5w6fw6q 5320 7 dl dl NNP cord-006870-f5w6fw6q 5320 8 ) ) -RRB- cord-006870-f5w6fw6q 5320 9 was be VBD cord-006870-f5w6fw6q 5320 10 associated associate VBN cord-006870-f5w6fw6q 5320 11 with with IN cord-006870-f5w6fw6q 5320 12 prolonged prolong VBN cord-006870-f5w6fw6q 5320 13 maxMTT maxmtt NN cord-006870-f5w6fw6q 5320 14 ( ( -LRB- cord-006870-f5w6fw6q 5320 15 p p NN cord-006870-f5w6fw6q 5320 16 < < XX cord-006870-f5w6fw6q 5320 17 .05 .05 XX cord-006870-f5w6fw6q 5320 18 , , , cord-006870-f5w6fw6q 5320 19 rs rs NN cord-006870-f5w6fw6q 5320 20 = = NNP cord-006870-f5w6fw6q 5320 21 .13 .13 NFP cord-006870-f5w6fw6q 5320 22 ) ) -RRB- cord-006870-f5w6fw6q 5320 23 and and CC cord-006870-f5w6fw6q 5320 24 was be VBD cord-006870-f5w6fw6q 5320 25 linked link VBN cord-006870-f5w6fw6q 5320 26 to to IN cord-006870-f5w6fw6q 5320 27 an an DT cord-006870-f5w6fw6q 5320 28 increased increase VBN cord-006870-f5w6fw6q 5320 29 risk risk NN cord-006870-f5w6fw6q 5320 30 of of IN cord-006870-f5w6fw6q 5320 31 infarction infarction NN cord-006870-f5w6fw6q 5320 32 ( ( -LRB- cord-006870-f5w6fw6q 5320 33 p p NN cord-006870-f5w6fw6q 5320 34 < < XX cord-006870-f5w6fw6q 5320 35 .001 .001 CD cord-006870-f5w6fw6q 5320 36 ) ) -RRB- cord-006870-f5w6fw6q 5320 37 whereas whereas IN cord-006870-f5w6fw6q 5320 38 strict strict JJ cord-006870-f5w6fw6q 5320 39 glucose glucose NN cord-006870-f5w6fw6q 5320 40 control control NN cord-006870-f5w6fw6q 5320 41 ( ( -LRB- cord-006870-f5w6fw6q 5320 42 110 110 CD cord-006870-f5w6fw6q 5320 43 - - SYM cord-006870-f5w6fw6q 5320 44 140 140 CD cord-006870-f5w6fw6q 5320 45 mg mg NNP cord-006870-f5w6fw6q 5320 46 / / SYM cord-006870-f5w6fw6q 5320 47 dl dl NNP cord-006870-f5w6fw6q 5320 48 ) ) -RRB- cord-006870-f5w6fw6q 5320 49 correlated correlate VBD cord-006870-f5w6fw6q 5320 50 significantly significantly RB cord-006870-f5w6fw6q 5320 51 negative negative JJ cord-006870-f5w6fw6q 5320 52 with with IN cord-006870-f5w6fw6q 5320 53 maxMTT maxMTT NNP cord-006870-f5w6fw6q 5320 54 ( ( -LRB- cord-006870-f5w6fw6q 5320 55 p p NN cord-006870-f5w6fw6q 5320 56 < < XX cord-006870-f5w6fw6q 5320 57 .05 .05 XX cord-006870-f5w6fw6q 5320 58 , , , cord-006870-f5w6fw6q 5320 59 rs rs NN cord-006870-f5w6fw6q 5320 60 = = SYM cord-006870-f5w6fw6q 5320 61 -.17 -.17 NN cord-006870-f5w6fw6q 5320 62 ) ) -RRB- cord-006870-f5w6fw6q 5320 63 . . . cord-006870-f5w6fw6q 5321 1 Strict strict JJ cord-006870-f5w6fw6q 5321 2 glucose glucose NN cord-006870-f5w6fw6q 5321 3 control control NN cord-006870-f5w6fw6q 5321 4 was be VBD cord-006870-f5w6fw6q 5321 5 also also RB cord-006870-f5w6fw6q 5321 6 associated associate VBN cord-006870-f5w6fw6q 5321 7 with with IN cord-006870-f5w6fw6q 5321 8 a a DT cord-006870-f5w6fw6q 5321 9 lower low JJR cord-006870-f5w6fw6q 5321 10 occurrence occurrence NN cord-006870-f5w6fw6q 5321 11 of of IN cord-006870-f5w6fw6q 5321 12 cerebral cerebral JJ cord-006870-f5w6fw6q 5321 13 infarction infarction NN cord-006870-f5w6fw6q 5321 14 and and CC cord-006870-f5w6fw6q 5321 15 good good JJ cord-006870-f5w6fw6q 5321 16 outcome outcome NN cord-006870-f5w6fw6q 5321 17 ( ( -LRB- cord-006870-f5w6fw6q 5321 18 p p NN cord-006870-f5w6fw6q 5321 19 < < XX cord-006870-f5w6fw6q 5321 20 .001 .001 XX cord-006870-f5w6fw6q 5321 21 , , , cord-006870-f5w6fw6q 5322 1 rs rs NNP cord-006870-f5w6fw6q 5322 2 = = SYM cord-006870-f5w6fw6q 5322 3 .47 .47 CD cord-006870-f5w6fw6q 5322 4 ) ) -RRB- cord-006870-f5w6fw6q 5322 5 . . . cord-006870-f5w6fw6q 5323 1 In in IN cord-006870-f5w6fw6q 5323 2 contrast contrast NN cord-006870-f5w6fw6q 5323 3 , , , cord-006870-f5w6fw6q 5323 4 elevated elevated JJ cord-006870-f5w6fw6q 5323 5 blood blood NN cord-006870-f5w6fw6q 5323 6 glucose glucose NN cord-006870-f5w6fw6q 5323 7 levels level NNS cord-006870-f5w6fw6q 5323 8 ( ( -LRB- cord-006870-f5w6fw6q 5323 9 140 140 CD cord-006870-f5w6fw6q 5323 10 - - SYM cord-006870-f5w6fw6q 5323 11 180 180 CD cord-006870-f5w6fw6q 5323 12 mg mg NNP cord-006870-f5w6fw6q 5323 13 / / SYM cord-006870-f5w6fw6q 5323 14 dl dl NNP cord-006870-f5w6fw6q 5323 15 ) ) -RRB- cord-006870-f5w6fw6q 5323 16 and and CC cord-006870-f5w6fw6q 5323 17 hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 5323 18 showed show VBD cord-006870-f5w6fw6q 5323 19 a a DT cord-006870-f5w6fw6q 5323 20 negative negative JJ cord-006870-f5w6fw6q 5323 21 correlation correlation NN cord-006870-f5w6fw6q 5323 22 with with IN cord-006870-f5w6fw6q 5323 23 good good JJ cord-006870-f5w6fw6q 5323 24 outcome outcome NN cord-006870-f5w6fw6q 5323 25 ( ( -LRB- cord-006870-f5w6fw6q 5324 1 p p LS cord-006870-f5w6fw6q 5324 2 < < XX cord-006870-f5w6fw6q 5324 3 .001 .001 XX cord-006870-f5w6fw6q 5324 4 , , , cord-006870-f5w6fw6q 5324 5 rs rs NNP cord-006870-f5w6fw6q 5324 6 = = SYM cord-006870-f5w6fw6q 5324 7 -.26 -.26 NN cord-006870-f5w6fw6q 5324 8 , , , cord-006870-f5w6fw6q 5324 9 rs rs NNP cord-006870-f5w6fw6q 5324 10 = = NNP cord-006870-f5w6fw6q 5324 11 -.35 -.35 NN cord-006870-f5w6fw6q 5324 12 ) ) -RRB- cord-006870-f5w6fw6q 5324 13 . . . cord-006870-f5w6fw6q 5325 1 The the DT cord-006870-f5w6fw6q 5325 2 present present JJ cord-006870-f5w6fw6q 5325 3 analysis analysis NN cord-006870-f5w6fw6q 5325 4 supports support VBZ cord-006870-f5w6fw6q 5325 5 for for IN cord-006870-f5w6fw6q 5325 6 the the DT cord-006870-f5w6fw6q 5325 7 first first JJ cord-006870-f5w6fw6q 5325 8 time time NN cord-006870-f5w6fw6q 5325 9 the the DT cord-006870-f5w6fw6q 5325 10 assumption assumption NN cord-006870-f5w6fw6q 5325 11 that that IN cord-006870-f5w6fw6q 5325 12 dysregulation dysregulation NN cord-006870-f5w6fw6q 5325 13 of of IN cord-006870-f5w6fw6q 5325 14 blood blood NN cord-006870-f5w6fw6q 5325 15 glucose glucose NN cord-006870-f5w6fw6q 5325 16 balance balance NN cord-006870-f5w6fw6q 5325 17 influences influence VBZ cord-006870-f5w6fw6q 5325 18 cerebral cerebral JJ cord-006870-f5w6fw6q 5325 19 perfusion perfusion NN cord-006870-f5w6fw6q 5325 20 and and CC cord-006870-f5w6fw6q 5325 21 thus thus RB cord-006870-f5w6fw6q 5325 22 may may MD cord-006870-f5w6fw6q 5325 23 contribute contribute VB cord-006870-f5w6fw6q 5325 24 to to IN cord-006870-f5w6fw6q 5325 25 the the DT cord-006870-f5w6fw6q 5325 26 occurrence occurrence NN cord-006870-f5w6fw6q 5325 27 of of IN cord-006870-f5w6fw6q 5325 28 DCI DCI NNP cord-006870-f5w6fw6q 5325 29 and and CC cord-006870-f5w6fw6q 5325 30 poor poor JJ cord-006870-f5w6fw6q 5325 31 outcome outcome NN cord-006870-f5w6fw6q 5325 32 . . . cord-006870-f5w6fw6q 5326 1 Therefore therefore RB cord-006870-f5w6fw6q 5326 2 careful careful JJ cord-006870-f5w6fw6q 5326 3 monitoring monitoring NN cord-006870-f5w6fw6q 5326 4 and and CC cord-006870-f5w6fw6q 5326 5 prompt prompt JJ cord-006870-f5w6fw6q 5326 6 treatment treatment NN cord-006870-f5w6fw6q 5326 7 of of IN cord-006870-f5w6fw6q 5326 8 blood blood NN cord-006870-f5w6fw6q 5326 9 glucose glucose NN cord-006870-f5w6fw6q 5326 10 levels level NNS cord-006870-f5w6fw6q 5326 11 after after IN cord-006870-f5w6fw6q 5326 12 aSAH asah JJ cord-006870-f5w6fw6q 5326 13 should should MD cord-006870-f5w6fw6q 5326 14 be be VB cord-006870-f5w6fw6q 5326 15 highly highly RB cord-006870-f5w6fw6q 5326 16 valued value VBN cord-006870-f5w6fw6q 5326 17 to to TO cord-006870-f5w6fw6q 5326 18 avoid avoid VB cord-006870-f5w6fw6q 5326 19 cerebral cerebral JJ cord-006870-f5w6fw6q 5326 20 perfusion perfusion NN cord-006870-f5w6fw6q 5326 21 deficits deficit NNS cord-006870-f5w6fw6q 5326 22 correlated correlate VBN cord-006870-f5w6fw6q 5326 23 with with IN cord-006870-f5w6fw6q 5326 24 poor poor JJ cord-006870-f5w6fw6q 5326 25 outcome outcome NN cord-006870-f5w6fw6q 5326 26 . . . cord-006870-f5w6fw6q 5327 1 The the DT cord-006870-f5w6fw6q 5327 2 aim aim NN cord-006870-f5w6fw6q 5327 3 of of IN cord-006870-f5w6fw6q 5327 4 this this DT cord-006870-f5w6fw6q 5327 5 study study NN cord-006870-f5w6fw6q 5327 6 was be VBD cord-006870-f5w6fw6q 5327 7 to to TO cord-006870-f5w6fw6q 5327 8 determine determine VB cord-006870-f5w6fw6q 5327 9 the the DT cord-006870-f5w6fw6q 5327 10 correlation correlation NN cord-006870-f5w6fw6q 5327 11 between between IN cord-006870-f5w6fw6q 5327 12 Transcranial Transcranial NNP cord-006870-f5w6fw6q 5327 13 Doppler Doppler NNP cord-006870-f5w6fw6q 5327 14 ( ( -LRB- cord-006870-f5w6fw6q 5327 15 TCD TCD NNP cord-006870-f5w6fw6q 5327 16 ) ) -RRB- cord-006870-f5w6fw6q 5327 17 velocities velocity NNS cord-006870-f5w6fw6q 5327 18 and and CC cord-006870-f5w6fw6q 5327 19 angiographic angiographic JJ cord-006870-f5w6fw6q 5327 20 vasospasm vasospasm NN cord-006870-f5w6fw6q 5327 21 after after IN cord-006870-f5w6fw6q 5327 22 Subarachnoid Subarachnoid NNP cord-006870-f5w6fw6q 5327 23 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5327 24 ( ( -LRB- cord-006870-f5w6fw6q 5327 25 SAH SAH NNP cord-006870-f5w6fw6q 5327 26 ) ) -RRB- cord-006870-f5w6fw6q 5327 27 . . . cord-006870-f5w6fw6q 5328 1 Methods method NNS cord-006870-f5w6fw6q 5328 2 221 221 CD cord-006870-f5w6fw6q 5328 3 patients patient NNS cord-006870-f5w6fw6q 5328 4 with with IN cord-006870-f5w6fw6q 5328 5 SAH SAH NNP cord-006870-f5w6fw6q 5328 6 were be VBD cord-006870-f5w6fw6q 5328 7 evaluated evaluate VBN cord-006870-f5w6fw6q 5328 8 with with IN cord-006870-f5w6fw6q 5328 9 Spencer Spencer NNP cord-006870-f5w6fw6q 5328 10 Technologies Technologies NNP cord-006870-f5w6fw6q 5328 11 TCD TCD NNP cord-006870-f5w6fw6q 5328 12 Power Power NNP cord-006870-f5w6fw6q 5328 13 M M NNP cord-006870-f5w6fw6q 5328 14 Mode Mode NNP cord-006870-f5w6fw6q 5328 15 from from IN cord-006870-f5w6fw6q 5328 16 2 2 CD cord-006870-f5w6fw6q 5328 17 - - SYM cord-006870-f5w6fw6q 5328 18 14 14 CD cord-006870-f5w6fw6q 5328 19 days day NNS cord-006870-f5w6fw6q 5328 20 , , , cord-006870-f5w6fw6q 5328 21 following follow VBG cord-006870-f5w6fw6q 5328 22 the the DT cord-006870-f5w6fw6q 5328 23 SAH SAH NNP cord-006870-f5w6fw6q 5328 24 . . . cord-006870-f5w6fw6q 5329 1 Both both DT cord-006870-f5w6fw6q 5329 2 the the DT cord-006870-f5w6fw6q 5329 3 Temporal temporal JJ cord-006870-f5w6fw6q 5329 4 windows window NNS cord-006870-f5w6fw6q 5329 5 were be VBD cord-006870-f5w6fw6q 5329 6 insonnated insonnate VBN cord-006870-f5w6fw6q 5329 7 to to TO cord-006870-f5w6fw6q 5329 8 determine determine VB cord-006870-f5w6fw6q 5329 9 flow flow NN cord-006870-f5w6fw6q 5329 10 velocities velocity NNS cord-006870-f5w6fw6q 5329 11 in in IN cord-006870-f5w6fw6q 5329 12 the the DT cord-006870-f5w6fw6q 5329 13 middle middle JJ cord-006870-f5w6fw6q 5329 14 ( ( -LRB- cord-006870-f5w6fw6q 5329 15 MCA MCA NNP cord-006870-f5w6fw6q 5329 16 ) ) -RRB- cord-006870-f5w6fw6q 5329 17 and and CC cord-006870-f5w6fw6q 5329 18 anterior anterior JJ cord-006870-f5w6fw6q 5329 19 cerebral cerebral JJ cord-006870-f5w6fw6q 5329 20 arteries artery NNS cord-006870-f5w6fw6q 5329 21 ( ( -LRB- cord-006870-f5w6fw6q 5329 22 ACA ACA NNP cord-006870-f5w6fw6q 5329 23 ) ) -RRB- cord-006870-f5w6fw6q 5329 24 and and CC cord-006870-f5w6fw6q 5329 25 the the DT cord-006870-f5w6fw6q 5329 26 suboccipital suboccipital JJ cord-006870-f5w6fw6q 5329 27 widow widow NN cord-006870-f5w6fw6q 5329 28 was be VBD cord-006870-f5w6fw6q 5329 29 used use VBN cord-006870-f5w6fw6q 5329 30 to to TO cord-006870-f5w6fw6q 5329 31 determine determine VB cord-006870-f5w6fw6q 5329 32 flow flow NN cord-006870-f5w6fw6q 5329 33 velocities velocity NNS cord-006870-f5w6fw6q 5329 34 in in IN cord-006870-f5w6fw6q 5329 35 the the DT cord-006870-f5w6fw6q 5329 36 vertebral vertebral JJ cord-006870-f5w6fw6q 5329 37 ( ( -LRB- cord-006870-f5w6fw6q 5329 38 VA VA NNP cord-006870-f5w6fw6q 5329 39 ) ) -RRB- cord-006870-f5w6fw6q 5329 40 and and CC cord-006870-f5w6fw6q 5329 41 Basilar Basilar NNP cord-006870-f5w6fw6q 5329 42 arteries artery NNS cord-006870-f5w6fw6q 5329 43 ( ( -LRB- cord-006870-f5w6fw6q 5329 44 BA BA NNP cord-006870-f5w6fw6q 5329 45 ) ) -RRB- cord-006870-f5w6fw6q 5329 46 . . . cord-006870-f5w6fw6q 5330 1 The the DT cord-006870-f5w6fw6q 5330 2 middle middle JJ cord-006870-f5w6fw6q 5330 3 cerebral cerebral JJ cord-006870-f5w6fw6q 5330 4 artery artery NN cord-006870-f5w6fw6q 5330 5 / / SYM cord-006870-f5w6fw6q 5330 6 ipsilateral ipsilateral JJ cord-006870-f5w6fw6q 5330 7 extracranial extracranial JJ cord-006870-f5w6fw6q 5330 8 internal internal JJ cord-006870-f5w6fw6q 5330 9 carotid carotid JJ cord-006870-f5w6fw6q 5330 10 artery artery NN cord-006870-f5w6fw6q 5330 11 velocity velocity NN cord-006870-f5w6fw6q 5330 12 ratio ratio NN cord-006870-f5w6fw6q 5330 13 ( ( -LRB- cord-006870-f5w6fw6q 5330 14 Lindegaard Lindegaard NNP cord-006870-f5w6fw6q 5330 15 ratio ratio NN cord-006870-f5w6fw6q 5330 16 ) ) -RRB- cord-006870-f5w6fw6q 5330 17 was be VBD cord-006870-f5w6fw6q 5330 18 also also RB cord-006870-f5w6fw6q 5330 19 correlated correlate VBN cord-006870-f5w6fw6q 5330 20 with with IN cord-006870-f5w6fw6q 5330 21 vasospasm vasospasm NN cord-006870-f5w6fw6q 5330 22 CT CT NNP cord-006870-f5w6fw6q 5330 23 Angiography Angiography NNP cord-006870-f5w6fw6q 5330 24 and and CC cord-006870-f5w6fw6q 5330 25 conventional conventional JJ cord-006870-f5w6fw6q 5330 26 cerebral cerebral JJ cord-006870-f5w6fw6q 5330 27 angiography angiography NN cord-006870-f5w6fw6q 5330 28 was be VBD cord-006870-f5w6fw6q 5330 29 used use VBN cord-006870-f5w6fw6q 5330 30 to to TO cord-006870-f5w6fw6q 5330 31 confirm confirm VB cord-006870-f5w6fw6q 5330 32 TCD TCD NNP cord-006870-f5w6fw6q 5330 33 findings finding NNS cord-006870-f5w6fw6q 5330 34 suggestive suggestive JJ cord-006870-f5w6fw6q 5330 35 of of IN cord-006870-f5w6fw6q 5330 36 Vasospasm Vasospasm NNP cord-006870-f5w6fw6q 5330 37 . . . cord-006870-f5w6fw6q 5331 1 The the DT cord-006870-f5w6fw6q 5331 2 sensitivity sensitivity NN cord-006870-f5w6fw6q 5331 3 , , , cord-006870-f5w6fw6q 5331 4 specificity specificity NN cord-006870-f5w6fw6q 5331 5 , , , cord-006870-f5w6fw6q 5331 6 likelihood likelihood NN cord-006870-f5w6fw6q 5331 7 ratios ratio NNS cord-006870-f5w6fw6q 5331 8 for for IN cord-006870-f5w6fw6q 5331 9 positive positive JJ cord-006870-f5w6fw6q 5331 10 and and CC cord-006870-f5w6fw6q 5331 11 negative negative JJ cord-006870-f5w6fw6q 5331 12 TCD TCD NNP cord-006870-f5w6fw6q 5331 13 results result NNS cord-006870-f5w6fw6q 5331 14 , , , cord-006870-f5w6fw6q 5331 15 positive positive JJ cord-006870-f5w6fw6q 5331 16 There there EX cord-006870-f5w6fw6q 5331 17 was be VBD cord-006870-f5w6fw6q 5331 18 131 131 CD cord-006870-f5w6fw6q 5331 19 males male NNS cord-006870-f5w6fw6q 5331 20 and and CC cord-006870-f5w6fw6q 5331 21 90 90 CD cord-006870-f5w6fw6q 5331 22 females female NNS cord-006870-f5w6fw6q 5331 23 and and CC cord-006870-f5w6fw6q 5331 24 with with IN cord-006870-f5w6fw6q 5331 25 mean mean JJ cord-006870-f5w6fw6q 5331 26 age age NN cord-006870-f5w6fw6q 5331 27 42.72 42.72 CD cord-006870-f5w6fw6q 5331 28 + + CD cord-006870-f5w6fw6q 5331 29 -7.6 -7.6 NN cord-006870-f5w6fw6q 5331 30 years year NNS cord-006870-f5w6fw6q 5331 31 . . . cord-006870-f5w6fw6q 5332 1 88 88 CD cord-006870-f5w6fw6q 5332 2 % % NN cord-006870-f5w6fw6q 5332 3 were be VBD cord-006870-f5w6fw6q 5332 4 Aneurysmal Aneurysmal NNP cord-006870-f5w6fw6q 5332 5 SAH SAH NNP cord-006870-f5w6fw6q 5332 6 . . . cord-006870-f5w6fw6q 5333 1 Delayed delay VBN cord-006870-f5w6fw6q 5333 2 ischemic ischemic JJ cord-006870-f5w6fw6q 5333 3 neurological neurological JJ cord-006870-f5w6fw6q 5333 4 deficits deficit NNS cord-006870-f5w6fw6q 5333 5 ( ( -LRB- cord-006870-f5w6fw6q 5333 6 DIND DIND NNP cord-006870-f5w6fw6q 5333 7 ) ) -RRB- cord-006870-f5w6fw6q 5333 8 developed develop VBD cord-006870-f5w6fw6q 5333 9 in in IN cord-006870-f5w6fw6q 5333 10 48/221 48/221 CD cord-006870-f5w6fw6q 5333 11 patients patient NNS cord-006870-f5w6fw6q 5333 12 ( ( -LRB- cord-006870-f5w6fw6q 5333 13 21.70 21.70 CD cord-006870-f5w6fw6q 5333 14 % % NN cord-006870-f5w6fw6q 5333 15 ) ) -RRB- cord-006870-f5w6fw6q 5333 16 . . . cord-006870-f5w6fw6q 5334 1 Interobserver Interobserver NNP cord-006870-f5w6fw6q 5334 2 ue ue NNP cord-006870-f5w6fw6q 5334 3 of of IN cord-006870-f5w6fw6q 5334 4 cm cm NNP cord-006870-f5w6fw6q 5334 5 / / SYM cord-006870-f5w6fw6q 5334 6 s s NNS cord-006870-f5w6fw6q 5334 7 were be VBD cord-006870-f5w6fw6q 5334 8 useful useful JJ cord-006870-f5w6fw6q 5334 9 ( ( -LRB- cord-006870-f5w6fw6q 5334 10 likelihood likelihood NN cord-006870-f5w6fw6q 5334 11 ratio ratio NN cord-006870-f5w6fw6q 5334 12 for for IN cord-006870-f5w6fw6q 5334 13 negative negative JJ cord-006870-f5w6fw6q 5334 14 result result NN cord-006870-f5w6fw6q 5334 15 = = SYM cord-006870-f5w6fw6q 5334 16 0.15 0.15 CD cord-006870-f5w6fw6q 5334 17 , , , cord-006870-f5w6fw6q 5334 18 likelihood likelihood NN cord-006870-f5w6fw6q 5334 19 ratio ratio NN cord-006870-f5w6fw6q 5334 20 for for IN cord-006870-f5w6fw6q 5334 21 positive positive JJ cord-006870-f5w6fw6q 5334 22 result result NN cord-006870-f5w6fw6q 5334 23 = = SYM cord-006870-f5w6fw6q 5334 24 14.89 14.89 CD cord-006870-f5w6fw6q 5334 25 ) ) -RRB- cord-006870-f5w6fw6q 5334 26 . . . cord-006870-f5w6fw6q 5335 1 Lindegaard Lindegaard NNP cord-006870-f5w6fw6q 5335 2 ratios ratio NNS cord-006870-f5w6fw6q 5335 3 correlated correlate VBD cord-006870-f5w6fw6q 5335 4 well well RB cord-006870-f5w6fw6q 5335 5 with with IN cord-006870-f5w6fw6q 5335 6 Vasospasm Vasospasm NNP cord-006870-f5w6fw6q 5335 7 . . . cord-006870-f5w6fw6q 5336 1 TCD TCD NNP cord-006870-f5w6fw6q 5336 2 diagnosis diagnosis NN cord-006870-f5w6fw6q 5336 3 of of IN cord-006870-f5w6fw6q 5336 4 Vasospasm Vasospasm NNP cord-006870-f5w6fw6q 5336 5 was be VBD cord-006870-f5w6fw6q 5336 6 more more RBR cord-006870-f5w6fw6q 5336 7 often often RB cord-006870-f5w6fw6q 5336 8 present present JJ cord-006870-f5w6fw6q 5336 9 in in IN cord-006870-f5w6fw6q 5336 10 the the DT cord-006870-f5w6fw6q 5336 11 MCA MCA NNP cord-006870-f5w6fw6q 5336 12 , , , cord-006870-f5w6fw6q 5336 13 followed follow VBN cord-006870-f5w6fw6q 5336 14 by by IN cord-006870-f5w6fw6q 5336 15 ACA ACA NNP cord-006870-f5w6fw6q 5336 16 and and CC cord-006870-f5w6fw6q 5336 17 Basilar Basilar NNP cord-006870-f5w6fw6q 5336 18 arteries artery NNS cord-006870-f5w6fw6q 5336 19 . . . cord-006870-f5w6fw6q 5337 1 TCD TCD NNP cord-006870-f5w6fw6q 5337 2 is be VBZ cord-006870-f5w6fw6q 5337 3 a a DT cord-006870-f5w6fw6q 5337 4 good good JJ cord-006870-f5w6fw6q 5337 5 non non AFX cord-006870-f5w6fw6q 5337 6 invasive invasive JJ cord-006870-f5w6fw6q 5337 7 method method NN cord-006870-f5w6fw6q 5337 8 to to TO cord-006870-f5w6fw6q 5337 9 detect detect VB cord-006870-f5w6fw6q 5337 10 Vasospasm Vasospasm NNP cord-006870-f5w6fw6q 5337 11 and and CC cord-006870-f5w6fw6q 5337 12 predict predict VB cord-006870-f5w6fw6q 5337 13 the the DT cord-006870-f5w6fw6q 5337 14 occurrence occurrence NN cord-006870-f5w6fw6q 5337 15 of of IN cord-006870-f5w6fw6q 5337 16 DIND DIND NNP cord-006870-f5w6fw6q 5337 17 . . . cord-006870-f5w6fw6q 5338 1 Very very RB cord-006870-f5w6fw6q 5338 2 high high JJ cord-006870-f5w6fw6q 5338 3 angiographic angiographic JJ cord-006870-f5w6fw6q 5338 4 vasospasm vasospasm NN cord-006870-f5w6fw6q 5338 5 . . . cord-006870-f5w6fw6q 5339 1 TCD TCD NNP cord-006870-f5w6fw6q 5339 2 is be VBZ cord-006870-f5w6fw6q 5339 3 also also RB cord-006870-f5w6fw6q 5339 4 useful useful JJ cord-006870-f5w6fw6q 5339 5 to to TO cord-006870-f5w6fw6q 5339 6 follow follow VB cord-006870-f5w6fw6q 5339 7 up up RP cord-006870-f5w6fw6q 5339 8 patients patient NNS cord-006870-f5w6fw6q 5339 9 with with IN cord-006870-f5w6fw6q 5339 10 angiographically angiographically RB cord-006870-f5w6fw6q 5339 11 proved prove VBN cord-006870-f5w6fw6q 5339 12 Vasospasm Vasospasm NNP cord-006870-f5w6fw6q 5339 13 . . . cord-006870-f5w6fw6q 5340 1 Aneurysmal Aneurysmal NNP cord-006870-f5w6fw6q 5340 2 Subarachnoid Subarachnoid NNP cord-006870-f5w6fw6q 5340 3 Hemorrhage Hemorrhage NNP cord-006870-f5w6fw6q 5340 4 ( ( -LRB- cord-006870-f5w6fw6q 5340 5 aSAH asah JJ cord-006870-f5w6fw6q 5340 6 ) ) -RRB- cord-006870-f5w6fw6q 5340 7 is be VBZ cord-006870-f5w6fw6q 5340 8 a a DT cord-006870-f5w6fw6q 5340 9 significant significant JJ cord-006870-f5w6fw6q 5340 10 cause cause NN cord-006870-f5w6fw6q 5340 11 of of IN cord-006870-f5w6fw6q 5340 12 morbidity morbidity NN cord-006870-f5w6fw6q 5340 13 and and CC cord-006870-f5w6fw6q 5340 14 mortality mortality NN cord-006870-f5w6fw6q 5340 15 . . . cord-006870-f5w6fw6q 5341 1 The the DT cord-006870-f5w6fw6q 5341 2 mortality mortality NN cord-006870-f5w6fw6q 5341 3 rate rate NN cord-006870-f5w6fw6q 5341 4 approaches approach NNS cord-006870-f5w6fw6q 5341 5 50 50 CD cord-006870-f5w6fw6q 5341 6 % % NN cord-006870-f5w6fw6q 5341 7 . . . cord-006870-f5w6fw6q 5342 1 Nearly nearly RB cord-006870-f5w6fw6q 5342 2 half half NN cord-006870-f5w6fw6q 5342 3 of of IN cord-006870-f5w6fw6q 5342 4 the the DT cord-006870-f5w6fw6q 5342 5 survivors survivor NNS cord-006870-f5w6fw6q 5342 6 remain remain VBP cord-006870-f5w6fw6q 5342 7 unable unable JJ cord-006870-f5w6fw6q 5342 8 to to TO cord-006870-f5w6fw6q 5342 9 care care VB cord-006870-f5w6fw6q 5342 10 for for IN cord-006870-f5w6fw6q 5342 11 themselves -PRON- PRP cord-006870-f5w6fw6q 5342 12 . . . cord-006870-f5w6fw6q 5343 1 DCI DCI NNP cord-006870-f5w6fw6q 5343 2 occurs occur VBZ cord-006870-f5w6fw6q 5343 3 in in IN cord-006870-f5w6fw6q 5343 4 29 29 CD cord-006870-f5w6fw6q 5343 5 % % NN cord-006870-f5w6fw6q 5343 6 of of IN cord-006870-f5w6fw6q 5343 7 these these DT cord-006870-f5w6fw6q 5343 8 patients patient NNS cord-006870-f5w6fw6q 5343 9 . . . cord-006870-f5w6fw6q 5344 1 When when WRB cord-006870-f5w6fw6q 5344 2 present present JJ cord-006870-f5w6fw6q 5344 3 , , , cord-006870-f5w6fw6q 5344 4 it -PRON- PRP cord-006870-f5w6fw6q 5344 5 doubles double VBZ cord-006870-f5w6fw6q 5344 6 the the DT cord-006870-f5w6fw6q 5344 7 risk risk NN cord-006870-f5w6fw6q 5344 8 of of IN cord-006870-f5w6fw6q 5344 9 poor poor JJ cord-006870-f5w6fw6q 5344 10 outcome outcome NN cord-006870-f5w6fw6q 5344 11 . . . cord-006870-f5w6fw6q 5345 1 -Several -several JJ cord-006870-f5w6fw6q 5345 2 methods method NNS cord-006870-f5w6fw6q 5345 3 have have VBP cord-006870-f5w6fw6q 5345 4 been be VBN cord-006870-f5w6fw6q 5345 5 used use VBN cord-006870-f5w6fw6q 5345 6 to to TO cord-006870-f5w6fw6q 5345 7 treat treat VB cord-006870-f5w6fw6q 5345 8 cerebral cerebral JJ cord-006870-f5w6fw6q 5345 9 vasospasm vasospasm NN cord-006870-f5w6fw6q 5345 10 and and CC cord-006870-f5w6fw6q 5345 11 DCI DCI NNP cord-006870-f5w6fw6q 5345 12 , , , cord-006870-f5w6fw6q 5345 13 which which WDT cord-006870-f5w6fw6q 5345 14 is be VBZ cord-006870-f5w6fw6q 5345 15 a a DT cord-006870-f5w6fw6q 5345 16 major major JJ cord-006870-f5w6fw6q 5345 17 cause cause NN cord-006870-f5w6fw6q 5345 18 of of IN cord-006870-f5w6fw6q 5345 19 morbidity morbidity NN cord-006870-f5w6fw6q 5345 20 and and CC cord-006870-f5w6fw6q 5345 21 mortality mortality NN cord-006870-f5w6fw6q 5345 22 in in IN cord-006870-f5w6fw6q 5345 23 patients patient NNS cord-006870-f5w6fw6q 5345 24 with with IN cord-006870-f5w6fw6q 5345 25 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5345 26 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5345 27 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5345 28 ( ( -LRB- cord-006870-f5w6fw6q 5345 29 SAH SAH NNP cord-006870-f5w6fw6q 5345 30 ) ) -RRB- cord-006870-f5w6fw6q 5345 31 . . . cord-006870-f5w6fw6q 5346 1 Milrinone Milrinone NNP cord-006870-f5w6fw6q 5346 2 safe safe JJ cord-006870-f5w6fw6q 5346 3 and and CC cord-006870-f5w6fw6q 5346 4 , , , cord-006870-f5w6fw6q 5346 5 potentially potentially RB cord-006870-f5w6fw6q 5346 6 , , , cord-006870-f5w6fw6q 5346 7 effective effective JJ cord-006870-f5w6fw6q 5346 8 treatment treatment NN cord-006870-f5w6fw6q 5346 9 of of IN cord-006870-f5w6fw6q 5346 10 DCI DCI NNP cord-006870-f5w6fw6q 5346 11 as as IN cord-006870-f5w6fw6q 5346 12 reported report VBN cord-006870-f5w6fw6q 5346 13 in in IN cord-006870-f5w6fw6q 5346 14 low low JJ cord-006870-f5w6fw6q 5346 15 level level NN cord-006870-f5w6fw6q 5346 16 of of IN cord-006870-f5w6fw6q 5346 17 evidence evidence NN cord-006870-f5w6fw6q 5346 18 literature literature NN cord-006870-f5w6fw6q 5346 19 . . . cord-006870-f5w6fw6q 5347 1 However however RB cord-006870-f5w6fw6q 5347 2 , , , cord-006870-f5w6fw6q 5347 3 the the DT cord-006870-f5w6fw6q 5347 4 efficacy efficacy NN cord-006870-f5w6fw6q 5347 5 not not RB cord-006870-f5w6fw6q 5347 6 compared compare VBN cord-006870-f5w6fw6q 5347 7 in in IN cord-006870-f5w6fw6q 5347 8 a a DT cord-006870-f5w6fw6q 5347 9 randomized randomized JJ cord-006870-f5w6fw6q 5347 10 way way NN cord-006870-f5w6fw6q 5347 11 to to IN cord-006870-f5w6fw6q 5347 12 placebo placebo NN cord-006870-f5w6fw6q 5347 13 . . . cord-006870-f5w6fw6q 5348 1 We -PRON- PRP cord-006870-f5w6fw6q 5348 2 will will MD cord-006870-f5w6fw6q 5348 3 examine examine VB cord-006870-f5w6fw6q 5348 4 the the DT cord-006870-f5w6fw6q 5348 5 effectiveness effectiveness NN cord-006870-f5w6fw6q 5348 6 and and CC cord-006870-f5w6fw6q 5348 7 safety safety NN cord-006870-f5w6fw6q 5348 8 of of IN cord-006870-f5w6fw6q 5348 9 intra intra JJ cord-006870-f5w6fw6q 5348 10 - - JJ cord-006870-f5w6fw6q 5348 11 venous venous JJ cord-006870-f5w6fw6q 5348 12 injection injection NN cord-006870-f5w6fw6q 5348 13 of of IN cord-006870-f5w6fw6q 5348 14 milrinone milrinone NN cord-006870-f5w6fw6q 5348 15 for for IN cord-006870-f5w6fw6q 5348 16 the the DT cord-006870-f5w6fw6q 5348 17 treatment treatment NN cord-006870-f5w6fw6q 5348 18 of of IN cord-006870-f5w6fw6q 5348 19 DCI DCI NNP cord-006870-f5w6fw6q 5348 20 following follow VBG cord-006870-f5w6fw6q 5348 21 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5348 22 sub sub JJ cord-006870-f5w6fw6q 5348 23 - - JJ cord-006870-f5w6fw6q 5348 24 arachnoid arachnoid JJ cord-006870-f5w6fw6q 5348 25 haemorrhage haemorrhage NN cord-006870-f5w6fw6q 5348 26 . . . cord-006870-f5w6fw6q 5349 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5349 2 intension intension NN cord-006870-f5w6fw6q 5349 3 is be VBZ cord-006870-f5w6fw6q 5349 4 to to TO cord-006870-f5w6fw6q 5349 5 study study VB cord-006870-f5w6fw6q 5349 6 the the DT cord-006870-f5w6fw6q 5349 7 outcome outcome NN cord-006870-f5w6fw6q 5349 8 of of IN cord-006870-f5w6fw6q 5349 9 using use VBG cord-006870-f5w6fw6q 5349 10 milrinone milrinone NNP cord-006870-f5w6fw6q 5349 11 as as IN cord-006870-f5w6fw6q 5349 12 an an DT cord-006870-f5w6fw6q 5349 13 addition addition NN cord-006870-f5w6fw6q 5349 14 to to IN cord-006870-f5w6fw6q 5349 15 current current JJ cord-006870-f5w6fw6q 5349 16 therapies therapy NNS cord-006870-f5w6fw6q 5349 17 such such JJ cord-006870-f5w6fw6q 5349 18 as as IN cord-006870-f5w6fw6q 5349 19 hypertensive hypertensive JJ cord-006870-f5w6fw6q 5349 20 therapy therapy NN cord-006870-f5w6fw6q 5349 21 are be VBP cord-006870-f5w6fw6q 5349 22 not not RB cord-006870-f5w6fw6q 5349 23 effective effective JJ cord-006870-f5w6fw6q 5349 24 enough enough RB cord-006870-f5w6fw6q 5349 25 , , , cord-006870-f5w6fw6q 5349 26 yet yet CC cord-006870-f5w6fw6q 5349 27 can can MD cord-006870-f5w6fw6q 5349 28 not not RB cord-006870-f5w6fw6q 5349 29 be be VB cord-006870-f5w6fw6q 5349 30 replaced replace VBN cord-006870-f5w6fw6q 5349 31 as as IN cord-006870-f5w6fw6q 5349 32 it -PRON- PRP cord-006870-f5w6fw6q 5349 33 is be VBZ cord-006870-f5w6fw6q 5349 34 Standard Standard NNP cord-006870-f5w6fw6q 5349 35 of of IN cord-006870-f5w6fw6q 5349 36 care care NN cord-006870-f5w6fw6q 5349 37 . . . cord-006870-f5w6fw6q 5350 1 As as IN cord-006870-f5w6fw6q 5350 2 intravenous intravenous JJ cord-006870-f5w6fw6q 5350 3 milrinone milrinone NN cord-006870-f5w6fw6q 5350 4 was be VBD cord-006870-f5w6fw6q 5350 5 not not RB cord-006870-f5w6fw6q 5350 6 yet yet RB cord-006870-f5w6fw6q 5350 7 shown show VBN cord-006870-f5w6fw6q 5350 8 to to TO cord-006870-f5w6fw6q 5350 9 have have VB cord-006870-f5w6fw6q 5350 10 an an DT cord-006870-f5w6fw6q 5350 11 affect affect NN cord-006870-f5w6fw6q 5350 12 in in IN cord-006870-f5w6fw6q 5350 13 DCI DCI NNP cord-006870-f5w6fw6q 5350 14 in in IN cord-006870-f5w6fw6q 5350 15 a a DT cord-006870-f5w6fw6q 5350 16 randomized randomized JJ cord-006870-f5w6fw6q 5350 17 controlled control VBN cord-006870-f5w6fw6q 5350 18 trial trial NN cord-006870-f5w6fw6q 5350 19 . . . cord-006870-f5w6fw6q 5351 1 This this DT cord-006870-f5w6fw6q 5351 2 pilot pilot NN cord-006870-f5w6fw6q 5351 3 trial trial NN cord-006870-f5w6fw6q 5351 4 is be VBZ cord-006870-f5w6fw6q 5351 5 a a DT cord-006870-f5w6fw6q 5351 6 step step NN cord-006870-f5w6fw6q 5351 7 towards towards IN cord-006870-f5w6fw6q 5351 8 that that DT cord-006870-f5w6fw6q 5351 9 study study NN cord-006870-f5w6fw6q 5351 10 . . . cord-006870-f5w6fw6q 5352 1 The the DT cord-006870-f5w6fw6q 5352 2 study study NN cord-006870-f5w6fw6q 5352 3 is be VBZ cord-006870-f5w6fw6q 5352 4 a a DT cord-006870-f5w6fw6q 5352 5 pilot pilot JJ cord-006870-f5w6fw6q 5352 6 trial trial NN cord-006870-f5w6fw6q 5352 7 of of IN cord-006870-f5w6fw6q 5352 8 a a DT cord-006870-f5w6fw6q 5352 9 randomized randomized JJ cord-006870-f5w6fw6q 5352 10 placebo placebo NN cord-006870-f5w6fw6q 5352 11 - - HYPH cord-006870-f5w6fw6q 5352 12 controlled control VBN cord-006870-f5w6fw6q 5352 13 double double JJ cord-006870-f5w6fw6q 5352 14 blind blind JJ cord-006870-f5w6fw6q 5352 15 trial trial NN cord-006870-f5w6fw6q 5352 16 testing test VBG cord-006870-f5w6fw6q 5352 17 the the DT cord-006870-f5w6fw6q 5352 18 potential potential JJ cord-006870-f5w6fw6q 5352 19 beneficial beneficial JJ cord-006870-f5w6fw6q 5352 20 effect effect NN cord-006870-f5w6fw6q 5352 21 of of IN cord-006870-f5w6fw6q 5352 22 Milrinone Milrinone NNP cord-006870-f5w6fw6q 5352 23 , , , cord-006870-f5w6fw6q 5352 24 a a DT cord-006870-f5w6fw6q 5352 25 phosphodiesterase phosphodiesterase NN cord-006870-f5w6fw6q 5352 26 inhibitor inhibitor NN cord-006870-f5w6fw6q 5352 27 , , , cord-006870-f5w6fw6q 5352 28 on on IN cord-006870-f5w6fw6q 5352 29 clinical clinical JJ cord-006870-f5w6fw6q 5352 30 neurological neurological JJ cord-006870-f5w6fw6q 5352 31 outcome outcome NN cord-006870-f5w6fw6q 5352 32 in in IN cord-006870-f5w6fw6q 5352 33 patients patient NNS cord-006870-f5w6fw6q 5352 34 with with IN cord-006870-f5w6fw6q 5352 35 DCI DCI NNP cord-006870-f5w6fw6q 5352 36 after after IN cord-006870-f5w6fw6q 5352 37 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5352 38 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5352 39 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5352 40 . . . cord-006870-f5w6fw6q 5353 1 The the DT cord-006870-f5w6fw6q 5353 2 study study NN cord-006870-f5w6fw6q 5353 3 drug drug NN cord-006870-f5w6fw6q 5353 4 will will MD cord-006870-f5w6fw6q 5353 5 be be VB cord-006870-f5w6fw6q 5353 6 given give VBN cord-006870-f5w6fw6q 5353 7 along along RP cord-006870-f5w6fw6q 5353 8 with with IN cord-006870-f5w6fw6q 5353 9 the the DT cord-006870-f5w6fw6q 5353 10 standard standard JJ cord-006870-f5w6fw6q 5353 11 therapy therapy NN cord-006870-f5w6fw6q 5353 12 when when WRB cord-006870-f5w6fw6q 5353 13 DCI DCI NNP cord-006870-f5w6fw6q 5353 14 occurs occur VBZ cord-006870-f5w6fw6q 5353 15 . . . cord-006870-f5w6fw6q 5354 1 The the DT cord-006870-f5w6fw6q 5354 2 administration administration NN cord-006870-f5w6fw6q 5354 3 of of IN cord-006870-f5w6fw6q 5354 4 milrinone milrinone NNP cord-006870-f5w6fw6q 5354 5 increases increase VBZ cord-006870-f5w6fw6q 5354 6 cerebral cerebral JJ cord-006870-f5w6fw6q 5354 7 blood blood NN cord-006870-f5w6fw6q 5354 8 flow flow NN cord-006870-f5w6fw6q 5354 9 most most RBS cord-006870-f5w6fw6q 5354 10 likely likely JJ cord-006870-f5w6fw6q 5354 11 as as IN cord-006870-f5w6fw6q 5354 12 a a DT cord-006870-f5w6fw6q 5354 13 result result NN cord-006870-f5w6fw6q 5354 14 Of of IN cord-006870-f5w6fw6q 5354 15 cerebral cerebral JJ cord-006870-f5w6fw6q 5354 16 vasodilation vasodilation NN cord-006870-f5w6fw6q 5354 17 . . . cord-006870-f5w6fw6q 5355 1 As as IN cord-006870-f5w6fw6q 5355 2 intravenous intravenous JJ cord-006870-f5w6fw6q 5355 3 milrinone milrinone NN cord-006870-f5w6fw6q 5355 4 was be VBD cord-006870-f5w6fw6q 5355 5 not not RB cord-006870-f5w6fw6q 5355 6 yet yet RB cord-006870-f5w6fw6q 5355 7 shown show VBN cord-006870-f5w6fw6q 5355 8 to to TO cord-006870-f5w6fw6q 5355 9 have have VB cord-006870-f5w6fw6q 5355 10 an an DT cord-006870-f5w6fw6q 5355 11 affect affect NN cord-006870-f5w6fw6q 5355 12 in in IN cord-006870-f5w6fw6q 5355 13 DCI DCI NNP cord-006870-f5w6fw6q 5355 14 in in IN cord-006870-f5w6fw6q 5355 15 a a DT cord-006870-f5w6fw6q 5355 16 randomized randomized JJ cord-006870-f5w6fw6q 5355 17 controlled control VBN cord-006870-f5w6fw6q 5355 18 trial trial NN cord-006870-f5w6fw6q 5355 19 . . . cord-006870-f5w6fw6q 5356 1 This this DT cord-006870-f5w6fw6q 5356 2 pilot pilot NN cord-006870-f5w6fw6q 5356 3 trial trial NN cord-006870-f5w6fw6q 5356 4 is be VBZ cord-006870-f5w6fw6q 5356 5 a a DT cord-006870-f5w6fw6q 5356 6 step step NN cord-006870-f5w6fw6q 5356 7 towards towards IN cord-006870-f5w6fw6q 5356 8 that that DT cord-006870-f5w6fw6q 5356 9 study study NN cord-006870-f5w6fw6q 5356 10 . . . cord-006870-f5w6fw6q 5357 1 Milirinone Milirinone NNP cord-006870-f5w6fw6q 5357 2 promising promising JJ cord-006870-f5w6fw6q 5357 3 treatment treatment NN cord-006870-f5w6fw6q 5357 4 for for IN cord-006870-f5w6fw6q 5357 5 delayed delay VBN cord-006870-f5w6fw6q 5357 6 cerebral cerebral JJ cord-006870-f5w6fw6q 5357 7 ischemia ischemia NN cord-006870-f5w6fw6q 5357 8 following follow VBG cord-006870-f5w6fw6q 5357 9 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 5357 10 sub sub JJ cord-006870-f5w6fw6q 5357 11 - - JJ cord-006870-f5w6fw6q 5357 12 arachnoid arachnoid JJ cord-006870-f5w6fw6q 5357 13 haemorrhage haemorrhage NN cord-006870-f5w6fw6q 5357 14 .particulary .particulary . cord-006870-f5w6fw6q 5358 1 by by IN cord-006870-f5w6fw6q 5358 2 using use VBG cord-006870-f5w6fw6q 5358 3 standardized standardized JJ cord-006870-f5w6fw6q 5358 4 protocol protocol NN cord-006870-f5w6fw6q 5358 5 as as IN cord-006870-f5w6fw6q 5358 6 a a DT cord-006870-f5w6fw6q 5358 7 finding finding NN cord-006870-f5w6fw6q 5358 8 suggestive suggestive JJ cord-006870-f5w6fw6q 5358 9 of of IN cord-006870-f5w6fw6q 5358 10 good good JJ cord-006870-f5w6fw6q 5358 11 prognosis prognosis NN cord-006870-f5w6fw6q 5358 12 Fever fever NN cord-006870-f5w6fw6q 5358 13 in in IN cord-006870-f5w6fw6q 5358 14 the the DT cord-006870-f5w6fw6q 5358 15 neurocritical neurocritical NNP cord-006870-f5w6fw6q 5358 16 care care NN cord-006870-f5w6fw6q 5358 17 population population NN cord-006870-f5w6fw6q 5358 18 is be VBZ cord-006870-f5w6fw6q 5358 19 very very RB cord-006870-f5w6fw6q 5358 20 common common JJ cord-006870-f5w6fw6q 5358 21 and and CC cord-006870-f5w6fw6q 5358 22 is be VBZ cord-006870-f5w6fw6q 5358 23 strongly strongly RB cord-006870-f5w6fw6q 5358 24 associated associate VBN cord-006870-f5w6fw6q 5358 25 with with IN cord-006870-f5w6fw6q 5358 26 increased increase VBN cord-006870-f5w6fw6q 5358 27 mortality mortality NN cord-006870-f5w6fw6q 5358 28 and and CC cord-006870-f5w6fw6q 5358 29 poor poor JJ cord-006870-f5w6fw6q 5358 30 outcome outcome NN cord-006870-f5w6fw6q 5358 31 . . . cord-006870-f5w6fw6q 5359 1 Fever fever NN cord-006870-f5w6fw6q 5359 2 is be VBZ cord-006870-f5w6fw6q 5359 3 aggressively aggressively RB cord-006870-f5w6fw6q 5359 4 treated treat VBN cord-006870-f5w6fw6q 5359 5 in in IN cord-006870-f5w6fw6q 5359 6 the the DT cord-006870-f5w6fw6q 5359 7 ICU ICU NNP cord-006870-f5w6fw6q 5359 8 due due IN cord-006870-f5w6fw6q 5359 9 to to IN cord-006870-f5w6fw6q 5359 10 its -PRON- PRP$ cord-006870-f5w6fw6q 5359 11 deleterious deleterious JJ cord-006870-f5w6fw6q 5359 12 effects effect NNS cord-006870-f5w6fw6q 5359 13 . . . cord-006870-f5w6fw6q 5360 1 Yet yet CC cord-006870-f5w6fw6q 5360 2 despite despite IN cord-006870-f5w6fw6q 5360 3 best good JJS cord-006870-f5w6fw6q 5360 4 efforts effort NNS cord-006870-f5w6fw6q 5360 5 with with IN cord-006870-f5w6fw6q 5360 6 standard standard JJ cord-006870-f5w6fw6q 5360 7 antipyretic antipyretic JJ cord-006870-f5w6fw6q 5360 8 agents agent NNS cord-006870-f5w6fw6q 5360 9 and and CC cord-006870-f5w6fw6q 5360 10 even even RB cord-006870-f5w6fw6q 5360 11 with with IN cord-006870-f5w6fw6q 5360 12 aggressive aggressive JJ cord-006870-f5w6fw6q 5360 13 cooling cool VBG cord-006870-f5w6fw6q 5360 14 measures measure NNS cord-006870-f5w6fw6q 5360 15 with with IN cord-006870-f5w6fw6q 5360 16 endovascular endovascular JJ cord-006870-f5w6fw6q 5360 17 cooling cool VBG cord-006870-f5w6fw6q 5360 18 catheters catheter NNS cord-006870-f5w6fw6q 5360 19 some some DT cord-006870-f5w6fw6q 5360 20 patients patient NNS cord-006870-f5w6fw6q 5360 21 may may MD cord-006870-f5w6fw6q 5360 22 still still RB cord-006870-f5w6fw6q 5360 23 have have VB cord-006870-f5w6fw6q 5360 24 refractory refractory JJ cord-006870-f5w6fw6q 5360 25 fevers fever NNS cord-006870-f5w6fw6q 5360 26 . . . cord-006870-f5w6fw6q 5361 1 Celecoxib Celecoxib NNP cord-006870-f5w6fw6q 5361 2 , , , cord-006870-f5w6fw6q 5361 3 a a DT cord-006870-f5w6fw6q 5361 4 cyclooxygenase-2 cyclooxygenase-2 NNP cord-006870-f5w6fw6q 5361 5 ( ( -LRB- cord-006870-f5w6fw6q 5361 6 COX-2 COX-2 NNP cord-006870-f5w6fw6q 5361 7 ) ) -RRB- cord-006870-f5w6fw6q 5361 8 inhibitor inhibitor NN cord-006870-f5w6fw6q 5361 9 , , , cord-006870-f5w6fw6q 5361 10 has have VBZ cord-006870-f5w6fw6q 5361 11 been be VBN cord-006870-f5w6fw6q 5361 12 used use VBN cord-006870-f5w6fw6q 5361 13 as as IN cord-006870-f5w6fw6q 5361 14 an an DT cord-006870-f5w6fw6q 5361 15 adjunctive adjunctive JJ cord-006870-f5w6fw6q 5361 16 antipyretic antipyretic JJ cord-006870-f5w6fw6q 5361 17 agent agent NN cord-006870-f5w6fw6q 5361 18 . . . cord-006870-f5w6fw6q 5362 1 This this DT cord-006870-f5w6fw6q 5362 2 is be VBZ cord-006870-f5w6fw6q 5362 3 a a DT cord-006870-f5w6fw6q 5362 4 retrospective retrospective JJ cord-006870-f5w6fw6q 5362 5 analysis analysis NN cord-006870-f5w6fw6q 5362 6 to to TO cord-006870-f5w6fw6q 5362 7 evaluate evaluate VB cord-006870-f5w6fw6q 5362 8 the the DT cord-006870-f5w6fw6q 5362 9 effectiveness effectiveness NN cord-006870-f5w6fw6q 5362 10 of of IN cord-006870-f5w6fw6q 5362 11 celecoxib celecoxib NNS cord-006870-f5w6fw6q 5362 12 in in IN cord-006870-f5w6fw6q 5362 13 lowering lower VBG cord-006870-f5w6fw6q 5362 14 temperatures temperature NNS cord-006870-f5w6fw6q 5362 15 in in IN cord-006870-f5w6fw6q 5362 16 patients patient NNS cord-006870-f5w6fw6q 5362 17 with with IN cord-006870-f5w6fw6q 5362 18 refractory refractory JJ cord-006870-f5w6fw6q 5362 19 fevers fever NNS cord-006870-f5w6fw6q 5362 20 . . . cord-006870-f5w6fw6q 5363 1 This this DT cord-006870-f5w6fw6q 5363 2 is be VBZ cord-006870-f5w6fw6q 5363 3 a a DT cord-006870-f5w6fw6q 5363 4 retrospective retrospective JJ cord-006870-f5w6fw6q 5363 5 chart chart NN cord-006870-f5w6fw6q 5363 6 review review NN cord-006870-f5w6fw6q 5363 7 of of IN cord-006870-f5w6fw6q 5363 8 patients patient NNS cord-006870-f5w6fw6q 5363 9 admitted admit VBN cord-006870-f5w6fw6q 5363 10 to to IN cord-006870-f5w6fw6q 5363 11 a a DT cord-006870-f5w6fw6q 5363 12 neurointensive neurointensive JJ cord-006870-f5w6fw6q 5363 13 care care NN cord-006870-f5w6fw6q 5363 14 unit unit NN cord-006870-f5w6fw6q 5363 15 at at IN cord-006870-f5w6fw6q 5363 16 a a DT cord-006870-f5w6fw6q 5363 17 single single JJ cord-006870-f5w6fw6q 5363 18 institution institution NN cord-006870-f5w6fw6q 5363 19 with with IN cord-006870-f5w6fw6q 5363 20 fevers fever NNS cord-006870-f5w6fw6q 5363 21 ( ( -LRB- cord-006870-f5w6fw6q 5363 22 > > XX cord-006870-f5w6fw6q 5364 1 38.3C 38.3c LS cord-006870-f5w6fw6q 5364 2 ) ) -RRB- cord-006870-f5w6fw6q 5364 3 that that WDT cord-006870-f5w6fw6q 5364 4 do do VBP cord-006870-f5w6fw6q 5364 5 not not RB cord-006870-f5w6fw6q 5364 6 respond respond VB cord-006870-f5w6fw6q 5364 7 to to IN cord-006870-f5w6fw6q 5364 8 convention convention NN cord-006870-f5w6fw6q 5364 9 treatment treatment NN cord-006870-f5w6fw6q 5364 10 with with IN cord-006870-f5w6fw6q 5364 11 acetaminophen acetaminophen NN cord-006870-f5w6fw6q 5364 12 , , , cord-006870-f5w6fw6q 5364 13 endovascular endovascular JJ cord-006870-f5w6fw6q 5364 14 cooling cool VBG cord-006870-f5w6fw6q 5364 15 catheters catheter NNS cord-006870-f5w6fw6q 5364 16 and and CC cord-006870-f5w6fw6q 5364 17 ibuprofen ibuprofen NN cord-006870-f5w6fw6q 5364 18 . . . cord-006870-f5w6fw6q 5365 1 83 83 CD cord-006870-f5w6fw6q 5365 2 patients patient NNS cord-006870-f5w6fw6q 5365 3 with with IN cord-006870-f5w6fw6q 5365 4 severe severe JJ cord-006870-f5w6fw6q 5365 5 traumatic traumatic JJ cord-006870-f5w6fw6q 5365 6 brain brain NN cord-006870-f5w6fw6q 5365 7 injury injury NN cord-006870-f5w6fw6q 5365 8 , , , cord-006870-f5w6fw6q 5365 9 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5365 10 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 5365 11 and and CC cord-006870-f5w6fw6q 5365 12 intracerebral intracerebral JJ cord-006870-f5w6fw6q 5365 13 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 5365 14 were be VBD cord-006870-f5w6fw6q 5365 15 included include VBN cord-006870-f5w6fw6q 5365 16 . . . cord-006870-f5w6fw6q 5366 1 Patient patient JJ cord-006870-f5w6fw6q 5366 2 temperature temperature NN cord-006870-f5w6fw6q 5366 3 recordings recording NNS cord-006870-f5w6fw6q 5366 4 were be VBD cord-006870-f5w6fw6q 5366 5 obtained obtain VBN cord-006870-f5w6fw6q 5366 6 in in IN cord-006870-f5w6fw6q 5366 7 the the DT cord-006870-f5w6fw6q 5366 8 period period NN cord-006870-f5w6fw6q 5366 9 of of IN cord-006870-f5w6fw6q 5366 10 24 24 CD cord-006870-f5w6fw6q 5366 11 hours hour NNS cord-006870-f5w6fw6q 5366 12 before before RB cord-006870-f5w6fw6q 5366 13 and and CC cord-006870-f5w6fw6q 5366 14 48 48 CD cord-006870-f5w6fw6q 5366 15 hours hour NNS cord-006870-f5w6fw6q 5366 16 after after IN cord-006870-f5w6fw6q 5366 17 administration administration NN cord-006870-f5w6fw6q 5366 18 to to IN cord-006870-f5w6fw6q 5366 19 the the DT cord-006870-f5w6fw6q 5366 20 first first JJ cord-006870-f5w6fw6q 5366 21 dose dose NN cord-006870-f5w6fw6q 5366 22 of of IN cord-006870-f5w6fw6q 5366 23 celecoxib celecoxib NNS cord-006870-f5w6fw6q 5366 24 . . . cord-006870-f5w6fw6q 5367 1 The the DT cord-006870-f5w6fw6q 5367 2 mean mean JJ cord-006870-f5w6fw6q 5367 3 temperature temperature NN cord-006870-f5w6fw6q 5367 4 of of IN cord-006870-f5w6fw6q 5367 5 the the DT cord-006870-f5w6fw6q 5367 6 before before NN cord-006870-f5w6fw6q 5367 7 and and CC cord-006870-f5w6fw6q 5367 8 after after IN cord-006870-f5w6fw6q 5367 9 periods period NNS cord-006870-f5w6fw6q 5367 10 were be VBD cord-006870-f5w6fw6q 5367 11 compared compare VBN cord-006870-f5w6fw6q 5367 12 and and CC cord-006870-f5w6fw6q 5367 13 temperature temperature NN cord-006870-f5w6fw6q 5367 14 difference difference NN cord-006870-f5w6fw6q 5367 15 was be VBD cord-006870-f5w6fw6q 5367 16 calculated calculate VBN cord-006870-f5w6fw6q 5367 17 . . . cord-006870-f5w6fw6q 5368 1 83 83 CD cord-006870-f5w6fw6q 5368 2 patient patient NN cord-006870-f5w6fw6q 5368 3 records record NNS cord-006870-f5w6fw6q 5368 4 were be VBD cord-006870-f5w6fw6q 5368 5 included include VBN cord-006870-f5w6fw6q 5368 6 . . . cord-006870-f5w6fw6q 5369 1 The the DT cord-006870-f5w6fw6q 5369 2 average average NN cord-006870-f5w6fw6q 5369 3 of of IN cord-006870-f5w6fw6q 5369 4 the the DT cord-006870-f5w6fw6q 5369 5 mean mean JJ cord-006870-f5w6fw6q 5369 6 temperatures temperature NNS cord-006870-f5w6fw6q 5369 7 in in IN cord-006870-f5w6fw6q 5369 8 the the DT cord-006870-f5w6fw6q 5369 9 before before JJ cord-006870-f5w6fw6q 5369 10 periods period NNS cord-006870-f5w6fw6q 5369 11 and and CC cord-006870-f5w6fw6q 5369 12 after after IN cord-006870-f5w6fw6q 5369 13 periods period NNS cord-006870-f5w6fw6q 5369 14 were be VBD cord-006870-f5w6fw6q 5369 15 37.79 37.79 CD cord-006870-f5w6fw6q 5369 16 C c NN cord-006870-f5w6fw6q 5369 17 ( ( -LRB- cord-006870-f5w6fw6q 5369 18 + + CC cord-006870-f5w6fw6q 5369 19 /-SEM /-sem SYM cord-006870-f5w6fw6q 5369 20 0.0659 0.0659 CD cord-006870-f5w6fw6q 5369 21 ) ) -RRB- cord-006870-f5w6fw6q 5369 22 and and CC cord-006870-f5w6fw6q 5369 23 37.37 37.37 CD cord-006870-f5w6fw6q 5369 24 C C NNP cord-006870-f5w6fw6q 5369 25 ( ( -LRB- cord-006870-f5w6fw6q 5369 26 + + CC cord-006870-f5w6fw6q 5369 27 /-SEM /-sem NN cord-006870-f5w6fw6q 5369 28 0.062 0.062 CD cord-006870-f5w6fw6q 5369 29 respectively respectively RB cord-006870-f5w6fw6q 5369 30 . . . cord-006870-f5w6fw6q 5370 1 There there EX cord-006870-f5w6fw6q 5370 2 was be VBD cord-006870-f5w6fw6q 5370 3 a a DT cord-006870-f5w6fw6q 5370 4 significant significant JJ cord-006870-f5w6fw6q 5370 5 difference difference NN cord-006870-f5w6fw6q 5370 6 on on IN cord-006870-f5w6fw6q 5370 7 Mann Mann NNP cord-006870-f5w6fw6q 5370 8 - - HYPH cord-006870-f5w6fw6q 5370 9 Whitney Whitney NNP cord-006870-f5w6fw6q 5370 10 - - HYPH cord-006870-f5w6fw6q 5370 11 Wilcoxon Wilcoxon NNP cord-006870-f5w6fw6q 5370 12 Rank Rank NNP cord-006870-f5w6fw6q 5370 13 Sum Sum NNP cord-006870-f5w6fw6q 5370 14 test test NN cord-006870-f5w6fw6q 5370 15 ( ( -LRB- cord-006870-f5w6fw6q 5370 16 p<0.000003 p<0.000003 NN cord-006870-f5w6fw6q 5370 17 ) ) -RRB- cord-006870-f5w6fw6q 5370 18 . . . cord-006870-f5w6fw6q 5371 1 One one CD cord-006870-f5w6fw6q 5371 2 average average NN cord-006870-f5w6fw6q 5371 3 there there EX cord-006870-f5w6fw6q 5371 4 was be VBD cord-006870-f5w6fw6q 5371 5 a a DT cord-006870-f5w6fw6q 5371 6 drop drop NN cord-006870-f5w6fw6q 5371 7 of of IN cord-006870-f5w6fw6q 5371 8 0.41(+/-SEM 0.41(+/-sem CD cord-006870-f5w6fw6q 5371 9 0.069 0.069 CD cord-006870-f5w6fw6q 5371 10 ) ) -RRB- cord-006870-f5w6fw6q 5372 1 degree degree NN cord-006870-f5w6fw6q 5372 2 Celsius Celsius NNP cord-006870-f5w6fw6q 5372 3 of of IN cord-006870-f5w6fw6q 5372 4 the the DT cord-006870-f5w6fw6q 5372 5 mean mean JJ cord-006870-f5w6fw6q 5372 6 temperature temperature NN cord-006870-f5w6fw6q 5372 7 after after IN cord-006870-f5w6fw6q 5372 8 the the DT cord-006870-f5w6fw6q 5372 9 start start NN cord-006870-f5w6fw6q 5372 10 of of IN cord-006870-f5w6fw6q 5372 11 treatment treatment NN cord-006870-f5w6fw6q 5372 12 . . . cord-006870-f5w6fw6q 5373 1 In in IN cord-006870-f5w6fw6q 5373 2 neurocritically neurocritically RB cord-006870-f5w6fw6q 5373 3 ill ill JJ cord-006870-f5w6fw6q 5373 4 patients patient NNS cord-006870-f5w6fw6q 5373 5 with with IN cord-006870-f5w6fw6q 5373 6 fevers fever NNS cord-006870-f5w6fw6q 5373 7 that that WDT cord-006870-f5w6fw6q 5373 8 are be VBP cord-006870-f5w6fw6q 5373 9 refractory refractory JJ cord-006870-f5w6fw6q 5373 10 to to IN cord-006870-f5w6fw6q 5373 11 conventional conventional JJ cord-006870-f5w6fw6q 5373 12 treatments treatment NNS cord-006870-f5w6fw6q 5373 13 adding add VBG cord-006870-f5w6fw6q 5373 14 celecoxib celecoxib NNP cord-006870-f5w6fw6q 5373 15 , , , cord-006870-f5w6fw6q 5373 16 a a DT cord-006870-f5w6fw6q 5373 17 COX-2 cox-2 JJ cord-006870-f5w6fw6q 5373 18 inhibitor inhibitor NN cord-006870-f5w6fw6q 5373 19 seems seem VBZ cord-006870-f5w6fw6q 5373 20 to to TO cord-006870-f5w6fw6q 5373 21 be be VB cord-006870-f5w6fw6q 5373 22 effective effective JJ cord-006870-f5w6fw6q 5373 23 at at IN cord-006870-f5w6fw6q 5373 24 lowering lower VBG cord-006870-f5w6fw6q 5373 25 the the DT cord-006870-f5w6fw6q 5373 26 core core NN cord-006870-f5w6fw6q 5373 27 body body NN cord-006870-f5w6fw6q 5373 28 temperature temperature NN cord-006870-f5w6fw6q 5373 29 . . . cord-006870-f5w6fw6q 5374 1 Further further JJ cord-006870-f5w6fw6q 5374 2 study study NN cord-006870-f5w6fw6q 5374 3 is be VBZ cord-006870-f5w6fw6q 5374 4 warranted warrant VBN cord-006870-f5w6fw6q 5374 5 to to TO cord-006870-f5w6fw6q 5374 6 evaluate evaluate VB cord-006870-f5w6fw6q 5374 7 for for IN cord-006870-f5w6fw6q 5374 8 adverse adverse JJ cord-006870-f5w6fw6q 5374 9 effects effect NNS cord-006870-f5w6fw6q 5374 10 such such JJ cord-006870-f5w6fw6q 5374 11 as as IN cord-006870-f5w6fw6q 5374 12 risk risk NN cord-006870-f5w6fw6q 5374 13 of of IN cord-006870-f5w6fw6q 5374 14 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 5374 15 events event NNS cord-006870-f5w6fw6q 5374 16 . . . cord-006870-f5w6fw6q 5375 1 Achieving achieve VBG cord-006870-f5w6fw6q 5375 2 and and CC cord-006870-f5w6fw6q 5375 3 maintaining maintain VBG cord-006870-f5w6fw6q 5375 4 normothermia normothermia NN cord-006870-f5w6fw6q 5375 5 ( ( -LRB- cord-006870-f5w6fw6q 5375 6 NT NT NNP cord-006870-f5w6fw6q 5375 7 ) ) -RRB- cord-006870-f5w6fw6q 5375 8 after after IN cord-006870-f5w6fw6q 5375 9 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5375 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5375 11 ( ( -LRB- cord-006870-f5w6fw6q 5375 12 SAH SAH NNP cord-006870-f5w6fw6q 5375 13 ) ) -RRB- cord-006870-f5w6fw6q 5375 14 or or CC cord-006870-f5w6fw6q 5375 15 intracerebral intracerebral JJ cord-006870-f5w6fw6q 5375 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5375 17 ( ( -LRB- cord-006870-f5w6fw6q 5375 18 ICH ICH NNP cord-006870-f5w6fw6q 5375 19 ) ) -RRB- cord-006870-f5w6fw6q 5375 20 often often RB cord-006870-f5w6fw6q 5375 21 requires require VBZ cord-006870-f5w6fw6q 5375 22 temperature temperature NN cord-006870-f5w6fw6q 5375 23 modulating modulate VBG cord-006870-f5w6fw6q 5375 24 devices device NNS cord-006870-f5w6fw6q 5375 25 ( ( -LRB- cord-006870-f5w6fw6q 5375 26 TMD TMD NNP cord-006870-f5w6fw6q 5375 27 ) ) -RRB- cord-006870-f5w6fw6q 5375 28 . . . cord-006870-f5w6fw6q 5376 1 Shivering shiver VBG cord-006870-f5w6fw6q 5376 2 is be VBZ cord-006870-f5w6fw6q 5376 3 a a DT cord-006870-f5w6fw6q 5376 4 common common JJ cord-006870-f5w6fw6q 5376 5 adverse adverse JJ cord-006870-f5w6fw6q 5376 6 effect effect NN cord-006870-f5w6fw6q 5376 7 of of IN cord-006870-f5w6fw6q 5376 8 TMD TMD NNP cord-006870-f5w6fw6q 5376 9 's 's POS cord-006870-f5w6fw6q 5376 10 that that WDT cord-006870-f5w6fw6q 5376 11 can can MD cord-006870-f5w6fw6q 5376 12 lead lead VB cord-006870-f5w6fw6q 5376 13 to to IN cord-006870-f5w6fw6q 5376 14 further further JJ cord-006870-f5w6fw6q 5376 15 costs cost NNS cord-006870-f5w6fw6q 5376 16 and and CC cord-006870-f5w6fw6q 5376 17 complications complication NNS cord-006870-f5w6fw6q 5376 18 . . . cord-006870-f5w6fw6q 5377 1 We -PRON- PRP cord-006870-f5w6fw6q 5377 2 evaluated evaluate VBD cord-006870-f5w6fw6q 5377 3 a a DT cord-006870-f5w6fw6q 5377 4 new new JJ cord-006870-f5w6fw6q 5377 5 esophageal esophageal JJ cord-006870-f5w6fw6q 5377 6 TMD TMD NNP cord-006870-f5w6fw6q 5377 7 , , , cord-006870-f5w6fw6q 5377 8 the the DT cord-006870-f5w6fw6q 5377 9 EnsoETM ensoetm NN cord-006870-f5w6fw6q 5377 10 ( ( -LRB- cord-006870-f5w6fw6q 5377 11 Attune Attune NNP cord-006870-f5w6fw6q 5377 12 Medical Medical NNP cord-006870-f5w6fw6q 5377 13 : : : cord-006870-f5w6fw6q 5377 14 Chicago Chicago NNP cord-006870-f5w6fw6q 5377 15 , , , cord-006870-f5w6fw6q 5377 16 IL IL NNP cord-006870-f5w6fw6q 5377 17 ) ) -RRB- cord-006870-f5w6fw6q 5377 18 , , , cord-006870-f5w6fw6q 5377 19 to to TO cord-006870-f5w6fw6q 5377 20 compare compare VB cord-006870-f5w6fw6q 5377 21 NT NT NNP cord-006870-f5w6fw6q 5377 22 performance performance NN cord-006870-f5w6fw6q 5377 23 , , , cord-006870-f5w6fw6q 5377 24 shiver shiver VB cord-006870-f5w6fw6q 5377 25 burden burden NN cord-006870-f5w6fw6q 5377 26 , , , cord-006870-f5w6fw6q 5377 27 and and CC cord-006870-f5w6fw6q 5377 28 cost cost NN cord-006870-f5w6fw6q 5377 29 of of IN cord-006870-f5w6fw6q 5377 30 shivering shiver VBG cord-006870-f5w6fw6q 5377 31 interventions intervention NNS cord-006870-f5w6fw6q 5377 32 with with IN cord-006870-f5w6fw6q 5377 33 existing exist VBG cord-006870-f5w6fw6q 5377 34 TMD TMD NNP cord-006870-f5w6fw6q 5377 35 's 's POS cord-006870-f5w6fw6q 5377 36 . . . cord-006870-f5w6fw6q 5378 1 Patients patient NNS cord-006870-f5w6fw6q 5378 2 with with IN cord-006870-f5w6fw6q 5378 3 SAH SAH NNP cord-006870-f5w6fw6q 5378 4 or or CC cord-006870-f5w6fw6q 5378 5 ICH ICH NNP cord-006870-f5w6fw6q 5378 6 and and CC cord-006870-f5w6fw6q 5378 7 refractory refractory JJ cord-006870-f5w6fw6q 5378 8 fever fever NN cord-006870-f5w6fw6q 5378 9 were be VBD cord-006870-f5w6fw6q 5378 10 treated treat VBN cord-006870-f5w6fw6q 5378 11 with with IN cord-006870-f5w6fw6q 5378 12 the the DT cord-006870-f5w6fw6q 5378 13 EnsoETM ensoetm NN cord-006870-f5w6fw6q 5378 14 . . . cord-006870-f5w6fw6q 5379 1 Patient patient JJ cord-006870-f5w6fw6q 5379 2 demographics demographic NNS cord-006870-f5w6fw6q 5379 3 , , , cord-006870-f5w6fw6q 5379 4 temperature temperature NN cord-006870-f5w6fw6q 5379 5 data datum NNS cord-006870-f5w6fw6q 5379 6 , , , cord-006870-f5w6fw6q 5379 7 shiver shiver VBP cord-006870-f5w6fw6q 5379 8 severity severity NN cord-006870-f5w6fw6q 5379 9 , , , cord-006870-f5w6fw6q 5379 10 and and CC cord-006870-f5w6fw6q 5379 11 amount amount NN cord-006870-f5w6fw6q 5379 12 and and CC cord-006870-f5w6fw6q 5379 13 costs cost NNS cord-006870-f5w6fw6q 5379 14 of of IN cord-006870-f5w6fw6q 5379 15 medication medication NN cord-006870-f5w6fw6q 5379 16 used use VBN cord-006870-f5w6fw6q 5379 17 for for IN cord-006870-f5w6fw6q 5379 18 shiver shiver NN cord-006870-f5w6fw6q 5379 19 management management NN cord-006870-f5w6fw6q 5379 20 were be VBD cord-006870-f5w6fw6q 5379 21 prospectively prospectively RB cord-006870-f5w6fw6q 5379 22 collected collect VBN cord-006870-f5w6fw6q 5379 23 . . . cord-006870-f5w6fw6q 5380 1 Control control NN cord-006870-f5w6fw6q 5380 2 patients patient NNS cord-006870-f5w6fw6q 5380 3 who who WP cord-006870-f5w6fw6q 5380 4 received receive VBD cord-006870-f5w6fw6q 5380 5 other other JJ cord-006870-f5w6fw6q 5380 6 TMDs tmd NNS cord-006870-f5w6fw6q 5380 7 were be VBD cord-006870-f5w6fw6q 5380 8 matched match VBN cord-006870-f5w6fw6q 5380 9 for for IN cord-006870-f5w6fw6q 5380 10 age age NN cord-006870-f5w6fw6q 5380 11 , , , cord-006870-f5w6fw6q 5380 12 gender gender NN cord-006870-f5w6fw6q 5380 13 , , , cord-006870-f5w6fw6q 5380 14 and and CC cord-006870-f5w6fw6q 5380 15 body body NN cord-006870-f5w6fw6q 5380 16 surface surface NN cord-006870-f5w6fw6q 5380 17 area area NN cord-006870-f5w6fw6q 5380 18 ( ( -LRB- cord-006870-f5w6fw6q 5380 19 BSA BSA NNP cord-006870-f5w6fw6q 5380 20 ) ) -RRB- cord-006870-f5w6fw6q 5380 21 to to IN cord-006870-f5w6fw6q 5380 22 EnsoETM ensoetm $ cord-006870-f5w6fw6q 5380 23 recipients recipient NNS cord-006870-f5w6fw6q 5380 24 and and CC cord-006870-f5w6fw6q 5380 25 similar similar JJ cord-006870-f5w6fw6q 5380 26 retrospective retrospective JJ cord-006870-f5w6fw6q 5380 27 data datum NNS cord-006870-f5w6fw6q 5380 28 was be VBD cord-006870-f5w6fw6q 5380 29 collected collect VBN cord-006870-f5w6fw6q 5380 30 . . . cord-006870-f5w6fw6q 5381 1 All all DT cord-006870-f5w6fw6q 5381 2 patients patient NNS cord-006870-f5w6fw6q 5381 3 were be VBD cord-006870-f5w6fw6q 5381 4 mechanically mechanically RB cord-006870-f5w6fw6q 5381 5 - - HYPH cord-006870-f5w6fw6q 5381 6 ventilated ventilate VBN cord-006870-f5w6fw6q 5381 7 . . . cord-006870-f5w6fw6q 5382 1 Fever fever NN cord-006870-f5w6fw6q 5382 2 burden burden NN cord-006870-f5w6fw6q 5382 3 was be VBD cord-006870-f5w6fw6q 5382 4 calculated calculate VBN cord-006870-f5w6fw6q 5382 5 as as IN cord-006870-f5w6fw6q 5382 6 areas area NNS cord-006870-f5w6fw6q 5382 7 of of IN cord-006870-f5w6fw6q 5382 8 curves curve NNS cord-006870-f5w6fw6q 5382 9 of of IN cord-006870-f5w6fw6q 5382 10 time time NN cord-006870-f5w6fw6q 5382 11 spent spend VBN cord-006870-f5w6fw6q 5382 12 above above IN cord-006870-f5w6fw6q 5382 13 37.5 37.5 CD cord-006870-f5w6fw6q 5382 14 or or CC cord-006870-f5w6fw6q 5382 15 38C. 38c. CD cord-006870-f5w6fw6q 5382 16 Demographics demographic NNS cord-006870-f5w6fw6q 5382 17 , , , cord-006870-f5w6fw6q 5382 18 temperature temperature NN cord-006870-f5w6fw6q 5382 19 data datum NNS cord-006870-f5w6fw6q 5382 20 , , , cord-006870-f5w6fw6q 5382 21 and and CC cord-006870-f5w6fw6q 5382 22 costs cost NNS cord-006870-f5w6fw6q 5382 23 of of IN cord-006870-f5w6fw6q 5382 24 EnsoETM ensoetm NN cord-006870-f5w6fw6q 5382 25 recipients recipient NNS cord-006870-f5w6fw6q 5382 26 were be VBD cord-006870-f5w6fw6q 5382 27 compared compare VBN cord-006870-f5w6fw6q 5382 28 to to IN cord-006870-f5w6fw6q 5382 29 recipients recipient NNS cord-006870-f5w6fw6q 5382 30 of of IN cord-006870-f5w6fw6q 5382 31 other other JJ cord-006870-f5w6fw6q 5382 32 TMD TMD NNP cord-006870-f5w6fw6q 5382 33 's 's POS cord-006870-f5w6fw6q 5382 34 . . . cord-006870-f5w6fw6q 5383 1 Eight eight CD cord-006870-f5w6fw6q 5383 2 EnsoETM ensoetm NN cord-006870-f5w6fw6q 5383 3 recipients recipient NNS cord-006870-f5w6fw6q 5383 4 and and CC cord-006870-f5w6fw6q 5383 5 24 24 CD cord-006870-f5w6fw6q 5383 6 controls control NNS cord-006870-f5w6fw6q 5383 7 between between IN cord-006870-f5w6fw6q 5383 8 October October NNP cord-006870-f5w6fw6q 5383 9 2015 2015 CD cord-006870-f5w6fw6q 5383 10 and and CC cord-006870-f5w6fw6q 5383 11 November November NNP cord-006870-f5w6fw6q 5383 12 2016 2016 CD cord-006870-f5w6fw6q 5383 13 were be VBD cord-006870-f5w6fw6q 5383 14 analyzed analyze VBN cord-006870-f5w6fw6q 5383 15 . . . cord-006870-f5w6fw6q 5384 1 There there EX cord-006870-f5w6fw6q 5384 2 were be VBD cord-006870-f5w6fw6q 5384 3 no no DT cord-006870-f5w6fw6q 5384 4 differences difference NNS cord-006870-f5w6fw6q 5384 5 between between IN cord-006870-f5w6fw6q 5384 6 the the DT cord-006870-f5w6fw6q 5384 7 two two CD cord-006870-f5w6fw6q 5384 8 groups group NNS cord-006870-f5w6fw6q 5384 9 in in IN cord-006870-f5w6fw6q 5384 10 demographics demographic NNS cord-006870-f5w6fw6q 5384 11 or or CC cord-006870-f5w6fw6q 5384 12 patient patient JJ cord-006870-f5w6fw6q 5384 13 characteristics characteristic NNS cord-006870-f5w6fw6q 5384 14 . . . cord-006870-f5w6fw6q 5385 1 No no DT cord-006870-f5w6fw6q 5385 2 difference difference NN cord-006870-f5w6fw6q 5385 3 was be VBD cord-006870-f5w6fw6q 5385 4 found find VBN cord-006870-f5w6fw6q 5385 5 in in IN cord-006870-f5w6fw6q 5385 6 temperature temperature NN cord-006870-f5w6fw6q 5385 7 at at IN cord-006870-f5w6fw6q 5385 8 initiation initiation NN cord-006870-f5w6fw6q 5385 9 ( ( -LRB- cord-006870-f5w6fw6q 5385 10 p p NN cord-006870-f5w6fw6q 5385 11 = = SYM cord-006870-f5w6fw6q 5385 12 0.4 0.4 CD cord-006870-f5w6fw6q 5385 13 ) ) -RRB- cord-006870-f5w6fw6q 5385 14 and and CC cord-006870-f5w6fw6q 5385 15 fever fever NN cord-006870-f5w6fw6q 5385 16 burden burden NN cord-006870-f5w6fw6q 5385 17 above above IN cord-006870-f5w6fw6q 5385 18 38 38 CD cord-006870-f5w6fw6q 5385 19 ° ° NN cord-006870-f5w6fw6q 5385 20 C c NN cord-006870-f5w6fw6q 5385 21 ( ( -LRB- cord-006870-f5w6fw6q 5385 22 p p NN cord-006870-f5w6fw6q 5385 23 = = SYM cord-006870-f5w6fw6q 5385 24 0.47 0.47 CD cord-006870-f5w6fw6q 5385 25 ) ) -RRB- cord-006870-f5w6fw6q 5385 26 . . . cord-006870-f5w6fw6q 5386 1 EnsoETM EnsoETM NNP cord-006870-f5w6fw6q 5386 2 recipients recipient NNS cord-006870-f5w6fw6q 5386 3 showed show VBD cord-006870-f5w6fw6q 5386 4 a a DT cord-006870-f5w6fw6q 5386 5 non non JJ cord-006870-f5w6fw6q 5386 6 - - JJ cord-006870-f5w6fw6q 5386 7 significant significant JJ cord-006870-f5w6fw6q 5386 8 trend trend NN cord-006870-f5w6fw6q 5386 9 in in IN cord-006870-f5w6fw6q 5386 10 taking take VBG cord-006870-f5w6fw6q 5386 11 longer long RBR cord-006870-f5w6fw6q 5386 12 to to TO cord-006870-f5w6fw6q 5386 13 achieve achieve VB cord-006870-f5w6fw6q 5386 14 NT NT NNP cord-006870-f5w6fw6q 5386 15 than than IN cord-006870-f5w6fw6q 5386 16 other other JJ cord-006870-f5w6fw6q 5386 17 TMD TMD NNP cord-006870-f5w6fw6q 5386 18 's 's POS cord-006870-f5w6fw6q 5386 19 ( ( -LRB- cord-006870-f5w6fw6q 5386 20 p p NN cord-006870-f5w6fw6q 5386 21 = = SYM cord-006870-f5w6fw6q 5386 22 0.07 0.07 CD cord-006870-f5w6fw6q 5386 23 ) ) -RRB- cord-006870-f5w6fw6q 5386 24 . . . cord-006870-f5w6fw6q 5387 1 EnsoETM EnsoETM NNP cord-006870-f5w6fw6q 5387 2 recipients recipient NNS cord-006870-f5w6fw6q 5387 3 required require VBD cord-006870-f5w6fw6q 5387 4 fewer few JJR cord-006870-f5w6fw6q 5387 5 shiver shiver NN cord-006870-f5w6fw6q 5387 6 interventions intervention NNS cord-006870-f5w6fw6q 5387 7 than than IN cord-006870-f5w6fw6q 5387 8 controls control NNS cord-006870-f5w6fw6q 5387 9 ( ( -LRB- cord-006870-f5w6fw6q 5387 10 p p NN cord-006870-f5w6fw6q 5387 11 = = SYM cord-006870-f5w6fw6q 5387 12 0.03 0.03 CD cord-006870-f5w6fw6q 5387 13 ) ) -RRB- cord-006870-f5w6fw6q 5387 14 . . . cord-006870-f5w6fw6q 5388 1 EnsoETM ensoetm NN cord-006870-f5w6fw6q 5388 2 recipients recipient NNS cord-006870-f5w6fw6q 5388 3 incurred incur VBD cord-006870-f5w6fw6q 5388 4 fewer few JJR cord-006870-f5w6fw6q 5388 5 costs cost NNS cord-006870-f5w6fw6q 5388 6 than than IN cord-006870-f5w6fw6q 5388 7 controls control NNS cord-006870-f5w6fw6q 5388 8 per per IN cord-006870-f5w6fw6q 5388 9 day day NN cord-006870-f5w6fw6q 5388 10 ( ( -LRB- cord-006870-f5w6fw6q 5388 11 p p NN cord-006870-f5w6fw6q 5388 12 = = SYM cord-006870-f5w6fw6q 5388 13 0.04 0.04 CD cord-006870-f5w6fw6q 5388 14 ) ) -RRB- cord-006870-f5w6fw6q 5388 15 . . . cord-006870-f5w6fw6q 5389 1 The the DT cord-006870-f5w6fw6q 5389 2 EnsoETM ensoetm NN cord-006870-f5w6fw6q 5389 3 achieved achieve VBN cord-006870-f5w6fw6q 5389 4 and and CC cord-006870-f5w6fw6q 5389 5 maintained maintain VBD cord-006870-f5w6fw6q 5389 6 NT NT NNP cord-006870-f5w6fw6q 5389 7 in in IN cord-006870-f5w6fw6q 5389 8 SAH SAH NNP cord-006870-f5w6fw6q 5389 9 and and CC cord-006870-f5w6fw6q 5389 10 ICH ICH NNP cord-006870-f5w6fw6q 5389 11 patients patient NNS cord-006870-f5w6fw6q 5389 12 and and CC cord-006870-f5w6fw6q 5389 13 was be VBD cord-006870-f5w6fw6q 5389 14 associated associate VBN cord-006870-f5w6fw6q 5389 15 with with IN cord-006870-f5w6fw6q 5389 16 less less JJR cord-006870-f5w6fw6q 5389 17 shivering shivering JJ cord-006870-f5w6fw6q 5389 18 and and CC cord-006870-f5w6fw6q 5389 19 lower low JJR cord-006870-f5w6fw6q 5389 20 pharmaceutical pharmaceutical NN cord-006870-f5w6fw6q 5389 21 costs cost NNS cord-006870-f5w6fw6q 5389 22 than than IN cord-006870-f5w6fw6q 5389 23 other other JJ cord-006870-f5w6fw6q 5389 24 TMD TMD NNP cord-006870-f5w6fw6q 5389 25 's 's POS cord-006870-f5w6fw6q 5389 26 . . . cord-006870-f5w6fw6q 5390 1 Further further JJ cord-006870-f5w6fw6q 5390 2 studies study NNS cord-006870-f5w6fw6q 5390 3 in in IN cord-006870-f5w6fw6q 5390 4 larger large JJR cord-006870-f5w6fw6q 5390 5 populations population NNS cord-006870-f5w6fw6q 5390 6 are be VBP cord-006870-f5w6fw6q 5390 7 needed need VBN cord-006870-f5w6fw6q 5390 8 to to TO cord-006870-f5w6fw6q 5390 9 determine determine VB cord-006870-f5w6fw6q 5390 10 the the DT cord-006870-f5w6fw6q 5390 11 EnsoETM ensoetm NN cord-006870-f5w6fw6q 5390 12 's 's POS cord-006870-f5w6fw6q 5390 13 efficacy efficacy NN cord-006870-f5w6fw6q 5390 14 in in IN cord-006870-f5w6fw6q 5390 15 comparison comparison NN cord-006870-f5w6fw6q 5390 16 to to IN cord-006870-f5w6fw6q 5390 17 other other JJ cord-006870-f5w6fw6q 5390 18 TMD TMD NNP cord-006870-f5w6fw6q 5390 19 's 's POS cord-006870-f5w6fw6q 5390 20 . . . cord-006870-f5w6fw6q 5391 1 Targeted target VBN cord-006870-f5w6fw6q 5391 2 temperature temperature NN cord-006870-f5w6fw6q 5391 3 management management NN cord-006870-f5w6fw6q 5391 4 is be VBZ cord-006870-f5w6fw6q 5391 5 an an DT cord-006870-f5w6fw6q 5391 6 important important JJ cord-006870-f5w6fw6q 5391 7 aspect aspect NN cord-006870-f5w6fw6q 5391 8 of of IN cord-006870-f5w6fw6q 5391 9 care care NN cord-006870-f5w6fw6q 5391 10 in in IN cord-006870-f5w6fw6q 5391 11 neurologically neurologically RB cord-006870-f5w6fw6q 5391 12 impaired impair VBN cord-006870-f5w6fw6q 5391 13 patients patient NNS cord-006870-f5w6fw6q 5391 14 . . . cord-006870-f5w6fw6q 5392 1 However however RB cord-006870-f5w6fw6q 5392 2 , , , cord-006870-f5w6fw6q 5392 3 achieving achieve VBG cord-006870-f5w6fw6q 5392 4 optimum optimum JJ cord-006870-f5w6fw6q 5392 5 temperature temperature NN cord-006870-f5w6fw6q 5392 6 for for IN cord-006870-f5w6fw6q 5392 7 a a DT cord-006870-f5w6fw6q 5392 8 specific specific JJ cord-006870-f5w6fw6q 5392 9 patient patient NN cord-006870-f5w6fw6q 5392 10 can can MD cord-006870-f5w6fw6q 5392 11 be be VB cord-006870-f5w6fw6q 5392 12 challenging challenging JJ cord-006870-f5w6fw6q 5392 13 ; ; : cord-006870-f5w6fw6q 5392 14 a a DT cord-006870-f5w6fw6q 5392 15 patient patient NN cord-006870-f5w6fw6q 5392 16 's 's POS cord-006870-f5w6fw6q 5392 17 size size NN cord-006870-f5w6fw6q 5392 18 , , , cord-006870-f5w6fw6q 5392 19 body body NN cord-006870-f5w6fw6q 5392 20 composition composition NN cord-006870-f5w6fw6q 5392 21 , , , cord-006870-f5w6fw6q 5392 22 metabolism metabolism NN cord-006870-f5w6fw6q 5392 23 , , , cord-006870-f5w6fw6q 5392 24 and and CC cord-006870-f5w6fw6q 5392 25 hypothalamic hypothalamic JJ cord-006870-f5w6fw6q 5392 26 function function NN cord-006870-f5w6fw6q 5392 27 contribute contribute VBP cord-006870-f5w6fw6q 5392 28 to to IN cord-006870-f5w6fw6q 5392 29 his -PRON- PRP$ cord-006870-f5w6fw6q 5392 30 or or CC cord-006870-f5w6fw6q 5392 31 her -PRON- PRP$ cord-006870-f5w6fw6q 5392 32 response response NN cord-006870-f5w6fw6q 5392 33 to to IN cord-006870-f5w6fw6q 5392 34 a a DT cord-006870-f5w6fw6q 5392 35 given give VBN cord-006870-f5w6fw6q 5392 36 temperature temperature NN cord-006870-f5w6fw6q 5392 37 management management NN cord-006870-f5w6fw6q 5392 38 modality modality NN cord-006870-f5w6fw6q 5392 39 . . . cord-006870-f5w6fw6q 5393 1 The the DT cord-006870-f5w6fw6q 5393 2 purpose purpose NN cord-006870-f5w6fw6q 5393 3 of of IN cord-006870-f5w6fw6q 5393 4 this this DT cord-006870-f5w6fw6q 5393 5 study study NN cord-006870-f5w6fw6q 5393 6 is be VBZ cord-006870-f5w6fw6q 5393 7 to to TO cord-006870-f5w6fw6q 5393 8 evaluate evaluate VB cord-006870-f5w6fw6q 5393 9 patient patient JJ cord-006870-f5w6fw6q 5393 10 response response NN cord-006870-f5w6fw6q 5393 11 to to IN cord-006870-f5w6fw6q 5393 12 esophageal esophageal JJ cord-006870-f5w6fw6q 5393 13 temperature temperature NN cord-006870-f5w6fw6q 5393 14 management management NN cord-006870-f5w6fw6q 5393 15 when when WRB cord-006870-f5w6fw6q 5393 16 continuously continuously RB cord-006870-f5w6fw6q 5393 17 applied apply VBD cord-006870-f5w6fw6q 5393 18 for for IN cord-006870-f5w6fw6q 5393 19 at at IN cord-006870-f5w6fw6q 5393 20 least least RBS cord-006870-f5w6fw6q 5393 21 72h 72h CD cord-006870-f5w6fw6q 5393 22 . . . cord-006870-f5w6fw6q 5394 1 Deidentified deidentifie VBN cord-006870-f5w6fw6q 5394 2 core core NN cord-006870-f5w6fw6q 5394 3 temperature temperature NN cord-006870-f5w6fw6q 5394 4 data datum NNS cord-006870-f5w6fw6q 5394 5 for for IN cord-006870-f5w6fw6q 5394 6 18 18 CD cord-006870-f5w6fw6q 5394 7 patients patient NNS cord-006870-f5w6fw6q 5394 8 ( ( -LRB- cord-006870-f5w6fw6q 5394 9 a a DT cord-006870-f5w6fw6q 5394 10 total total NN cord-006870-f5w6fw6q 5394 11 of of IN cord-006870-f5w6fw6q 5394 12 1237 1237 CD cord-006870-f5w6fw6q 5394 13 measurements measurement NNS cord-006870-f5w6fw6q 5394 14 ) ) -RRB- cord-006870-f5w6fw6q 5394 15 were be VBD cord-006870-f5w6fw6q 5394 16 obtained obtain VBN cord-006870-f5w6fw6q 5394 17 from from IN cord-006870-f5w6fw6q 5394 18 three three CD cord-006870-f5w6fw6q 5394 19 hospital hospital NN cord-006870-f5w6fw6q 5394 20 sites site NNS cord-006870-f5w6fw6q 5394 21 where where WRB cord-006870-f5w6fw6q 5394 22 esophageal esophageal JJ cord-006870-f5w6fw6q 5394 23 temperature temperature NN cord-006870-f5w6fw6q 5394 24 management management NN cord-006870-f5w6fw6q 5394 25 was be VBD cord-006870-f5w6fw6q 5394 26 used use VBN cord-006870-f5w6fw6q 5394 27 for for IN cord-006870-f5w6fw6q 5394 28 at at IN cord-006870-f5w6fw6q 5394 29 least least JJS cord-006870-f5w6fw6q 5394 30 72h 72h . cord-006870-f5w6fw6q 5394 31 ( ( -LRB- cord-006870-f5w6fw6q 5394 32 range range NNP cord-006870-f5w6fw6q 5394 33 72 72 CD cord-006870-f5w6fw6q 5394 34 - - HYPH cord-006870-f5w6fw6q 5394 35 452h 452h CD cord-006870-f5w6fw6q 5394 36 ) ) -RRB- cord-006870-f5w6fw6q 5394 37 . . . cord-006870-f5w6fw6q 5395 1 Indications indication NNS cord-006870-f5w6fw6q 5395 2 for for IN cord-006870-f5w6fw6q 5395 3 active active JJ cord-006870-f5w6fw6q 5395 4 temperature temperature NN cord-006870-f5w6fw6q 5395 5 management management NN cord-006870-f5w6fw6q 5395 6 included include VBD cord-006870-f5w6fw6q 5395 7 : : : cord-006870-f5w6fw6q 5395 8 cardiac cardiac JJ cord-006870-f5w6fw6q 5395 9 arrest arrest NN cord-006870-f5w6fw6q 5395 10 ( ( -LRB- cord-006870-f5w6fw6q 5395 11 7 7 CD cord-006870-f5w6fw6q 5395 12 ) ) -RRB- cord-006870-f5w6fw6q 5395 13 , , , cord-006870-f5w6fw6q 5395 14 refractory refractory JJ cord-006870-f5w6fw6q 5395 15 fever fever NN cord-006870-f5w6fw6q 5395 16 ( ( -LRB- cord-006870-f5w6fw6q 5395 17 4 4 CD cord-006870-f5w6fw6q 5395 18 ) ) -RRB- cord-006870-f5w6fw6q 5395 19 , , , cord-006870-f5w6fw6q 5395 20 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5395 21 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5395 22 ( ( -LRB- cord-006870-f5w6fw6q 5395 23 4 4 CD cord-006870-f5w6fw6q 5395 24 ) ) -RRB- cord-006870-f5w6fw6q 5395 25 , , , cord-006870-f5w6fw6q 5395 26 intracranial intracranial JJ cord-006870-f5w6fw6q 5395 27 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5395 28 ( ( -LRB- cord-006870-f5w6fw6q 5395 29 2 2 CD cord-006870-f5w6fw6q 5395 30 ) ) -RRB- cord-006870-f5w6fw6q 5395 31 , , , cord-006870-f5w6fw6q 5395 32 and and CC cord-006870-f5w6fw6q 5395 33 traumatic traumatic JJ cord-006870-f5w6fw6q 5395 34 brain brain NN cord-006870-f5w6fw6q 5395 35 injury injury NN cord-006870-f5w6fw6q 5395 36 ( ( -LRB- cord-006870-f5w6fw6q 5395 37 1 1 CD cord-006870-f5w6fw6q 5395 38 ) ) -RRB- cord-006870-f5w6fw6q 5395 39 . . . cord-006870-f5w6fw6q 5396 1 Goal goal NN cord-006870-f5w6fw6q 5396 2 temperatures temperature NNS cord-006870-f5w6fw6q 5396 3 ranged range VBD cord-006870-f5w6fw6q 5396 4 from from IN cord-006870-f5w6fw6q 5396 5 33 33 CD cord-006870-f5w6fw6q 5396 6 - - SYM cord-006870-f5w6fw6q 5396 7 38 38 CD cord-006870-f5w6fw6q 5396 8 ° ° NN cord-006870-f5w6fw6q 5396 9 C c NN cord-006870-f5w6fw6q 5396 10 and and CC cord-006870-f5w6fw6q 5396 11 initial initial JJ cord-006870-f5w6fw6q 5396 12 patient patient NN cord-006870-f5w6fw6q 5396 13 temperatures temperature NNS cord-006870-f5w6fw6q 5396 14 ranged range VBD cord-006870-f5w6fw6q 5396 15 from from IN cord-006870-f5w6fw6q 5396 16 35 35 CD cord-006870-f5w6fw6q 5396 17 - - SYM cord-006870-f5w6fw6q 5396 18 40 40 CD cord-006870-f5w6fw6q 5396 19 ° ° NN cord-006870-f5w6fw6q 5396 20 C c NN cord-006870-f5w6fw6q 5396 21 . . . cord-006870-f5w6fw6q 5397 1 Deviation deviation NN cord-006870-f5w6fw6q 5397 2 from from IN cord-006870-f5w6fw6q 5397 3 goal goal NN cord-006870-f5w6fw6q 5397 4 was be VBD cord-006870-f5w6fw6q 5397 5 calculated calculate VBN cord-006870-f5w6fw6q 5397 6 by by IN cord-006870-f5w6fw6q 5397 7 subtracting subtract VBG cord-006870-f5w6fw6q 5397 8 target target NN cord-006870-f5w6fw6q 5397 9 temperature temperature NN cord-006870-f5w6fw6q 5397 10 from from IN cord-006870-f5w6fw6q 5397 11 actual actual JJ cord-006870-f5w6fw6q 5397 12 temperature temperature NN cord-006870-f5w6fw6q 5397 13 for for IN cord-006870-f5w6fw6q 5397 14 each each DT cord-006870-f5w6fw6q 5397 15 measurement measurement NN cord-006870-f5w6fw6q 5397 16 which which WDT cord-006870-f5w6fw6q 5397 17 allowed allow VBD cord-006870-f5w6fw6q 5397 18 the the DT cord-006870-f5w6fw6q 5397 19 calculation calculation NN cord-006870-f5w6fw6q 5397 20 of of IN cord-006870-f5w6fw6q 5397 21 the the DT cord-006870-f5w6fw6q 5397 22 mean mean JJ cord-006870-f5w6fw6q 5397 23 and and CC cord-006870-f5w6fw6q 5397 24 standard standard JJ cord-006870-f5w6fw6q 5397 25 deviation deviation NN cord-006870-f5w6fw6q 5397 26 for for IN cord-006870-f5w6fw6q 5397 27 each each DT cord-006870-f5w6fw6q 5397 28 time time NN cord-006870-f5w6fw6q 5397 29 point point NN cord-006870-f5w6fw6q 5397 30 across across IN cord-006870-f5w6fw6q 5397 31 all all DT cord-006870-f5w6fw6q 5397 32 temperature temperature NN cord-006870-f5w6fw6q 5397 33 management management NN cord-006870-f5w6fw6q 5397 34 protocols protocol NNS cord-006870-f5w6fw6q 5397 35 . . . cord-006870-f5w6fw6q 5398 1 Across across IN cord-006870-f5w6fw6q 5398 2 129 129 CD cord-006870-f5w6fw6q 5398 3 time time NN cord-006870-f5w6fw6q 5398 4 points point NNS cord-006870-f5w6fw6q 5398 5 , , , cord-006870-f5w6fw6q 5398 6 representing represent VBG cord-006870-f5w6fw6q 5398 7 an an DT cord-006870-f5w6fw6q 5398 8 average average JJ cord-006870-f5w6fw6q 5398 9 treatment treatment NN cord-006870-f5w6fw6q 5398 10 time time NN cord-006870-f5w6fw6q 5398 11 of of IN cord-006870-f5w6fw6q 5398 12 137.7h 137.7h CD cord-006870-f5w6fw6q 5398 13 , , , cord-006870-f5w6fw6q 5398 14 95.3 95.3 CD cord-006870-f5w6fw6q 5398 15 % % NN cord-006870-f5w6fw6q 5398 16 of of IN cord-006870-f5w6fw6q 5398 17 mean mean JJ cord-006870-f5w6fw6q 5398 18 deviations deviation NNS cord-006870-f5w6fw6q 5398 19 from from IN cord-006870-f5w6fw6q 5398 20 goal goal NN cord-006870-f5w6fw6q 5398 21 were be VBD cord-006870-f5w6fw6q 5398 22 within within IN cord-006870-f5w6fw6q 5398 23 ±1 ±1 NNP cord-006870-f5w6fw6q 5398 24 ° ° NNP cord-006870-f5w6fw6q 5398 25 C c NN cord-006870-f5w6fw6q 5398 26 and and CC cord-006870-f5w6fw6q 5398 27 68.5 68.5 CD cord-006870-f5w6fw6q 5398 28 % % NN cord-006870-f5w6fw6q 5398 29 were be VBD cord-006870-f5w6fw6q 5398 30 within within IN cord-006870-f5w6fw6q 5398 31 ±0.5 ±0.5 NNP cord-006870-f5w6fw6q 5398 32 ° ° NNP cord-006870-f5w6fw6q 5398 33 C C NNP cord-006870-f5w6fw6q 5398 34 . . . cord-006870-f5w6fw6q 5399 1 In in IN cord-006870-f5w6fw6q 5399 2 interpreting interpret VBG cord-006870-f5w6fw6q 5399 3 these these DT cord-006870-f5w6fw6q 5399 4 results result NNS cord-006870-f5w6fw6q 5399 5 , , , cord-006870-f5w6fw6q 5399 6 several several JJ cord-006870-f5w6fw6q 5399 7 limitations limitation NNS cord-006870-f5w6fw6q 5399 8 must must MD cord-006870-f5w6fw6q 5399 9 be be VB cord-006870-f5w6fw6q 5399 10 considered consider VBN cord-006870-f5w6fw6q 5399 11 . . . cord-006870-f5w6fw6q 5400 1 This this DT cord-006870-f5w6fw6q 5400 2 dataset dataset NN cord-006870-f5w6fw6q 5400 3 reflects reflect VBZ cord-006870-f5w6fw6q 5400 4 a a DT cord-006870-f5w6fw6q 5400 5 wide wide JJ cord-006870-f5w6fw6q 5400 6 range range NN cord-006870-f5w6fw6q 5400 7 of of IN cord-006870-f5w6fw6q 5400 8 temperature temperature NN cord-006870-f5w6fw6q 5400 9 management management NN cord-006870-f5w6fw6q 5400 10 protocols protocol NNS cord-006870-f5w6fw6q 5400 11 and and CC cord-006870-f5w6fw6q 5400 12 clinical clinical JJ cord-006870-f5w6fw6q 5400 13 scenarios scenario NNS cord-006870-f5w6fw6q 5400 14 . . . cord-006870-f5w6fw6q 5401 1 For for IN cord-006870-f5w6fw6q 5401 2 example example NN cord-006870-f5w6fw6q 5401 3 , , , cord-006870-f5w6fw6q 5401 4 a a DT cord-006870-f5w6fw6q 5401 5 larger large JJR cord-006870-f5w6fw6q 5401 6 than than IN cord-006870-f5w6fw6q 5401 7 average average JJ cord-006870-f5w6fw6q 5401 8 deviation deviation NN cord-006870-f5w6fw6q 5401 9 in in IN cord-006870-f5w6fw6q 5401 10 measurements measurement NNS cord-006870-f5w6fw6q 5401 11 recorded record VBN cord-006870-f5w6fw6q 5401 12 in in IN cord-006870-f5w6fw6q 5401 13 the the DT cord-006870-f5w6fw6q 5401 14 24 24 CD cord-006870-f5w6fw6q 5401 15 - - HYPH cord-006870-f5w6fw6q 5401 16 36h 36h CD cord-006870-f5w6fw6q 5401 17 period period NN cord-006870-f5w6fw6q 5401 18 was be VBD cord-006870-f5w6fw6q 5401 19 related relate VBN cord-006870-f5w6fw6q 5401 20 to to IN cord-006870-f5w6fw6q 5401 21 rewarming rewarme VBG cord-006870-f5w6fw6q 5401 22 in in IN cord-006870-f5w6fw6q 5401 23 cardiac cardiac JJ cord-006870-f5w6fw6q 5401 24 arrest arrest NN cord-006870-f5w6fw6q 5401 25 patients patient NNS cord-006870-f5w6fw6q 5401 26 who who WP cord-006870-f5w6fw6q 5401 27 rewarmed rewarme VBD cord-006870-f5w6fw6q 5401 28 slowly slowly RB cord-006870-f5w6fw6q 5401 29 . . . cord-006870-f5w6fw6q 5402 1 Also also RB cord-006870-f5w6fw6q 5402 2 , , , cord-006870-f5w6fw6q 5402 3 the the DT cord-006870-f5w6fw6q 5402 4 later later JJ cord-006870-f5w6fw6q 5402 5 time time NN cord-006870-f5w6fw6q 5402 6 points point NNS cord-006870-f5w6fw6q 5402 7 were be VBD cord-006870-f5w6fw6q 5402 8 dominated dominate VBN cord-006870-f5w6fw6q 5402 9 by by IN cord-006870-f5w6fw6q 5402 10 SAH SAH NNP cord-006870-f5w6fw6q 5402 11 , , , cord-006870-f5w6fw6q 5402 12 ICH ICH NNP cord-006870-f5w6fw6q 5402 13 , , , cord-006870-f5w6fw6q 5402 14 and and CC cord-006870-f5w6fw6q 5402 15 refractory refractory JJ cord-006870-f5w6fw6q 5402 16 fever fever NN cord-006870-f5w6fw6q 5402 17 patients patient NNS cord-006870-f5w6fw6q 5402 18 who who WP cord-006870-f5w6fw6q 5402 19 often often RB cord-006870-f5w6fw6q 5402 20 experience experience VBP cord-006870-f5w6fw6q 5402 21 more more RBR cord-006870-f5w6fw6q 5402 22 pronounced pronounce VBN cord-006870-f5w6fw6q 5402 23 fever fever NN cord-006870-f5w6fw6q 5402 24 spikes spike NNS cord-006870-f5w6fw6q 5402 25 . . . cord-006870-f5w6fw6q 5403 1 This this DT cord-006870-f5w6fw6q 5403 2 analysis analysis NN cord-006870-f5w6fw6q 5403 3 indicates indicate VBZ cord-006870-f5w6fw6q 5403 4 that that IN cord-006870-f5w6fw6q 5403 5 esophageal esophageal JJ cord-006870-f5w6fw6q 5403 6 temperature temperature NN cord-006870-f5w6fw6q 5403 7 management management NN cord-006870-f5w6fw6q 5403 8 is be VBZ cord-006870-f5w6fw6q 5403 9 a a DT cord-006870-f5w6fw6q 5403 10 feasible feasible JJ cord-006870-f5w6fw6q 5403 11 option option NN cord-006870-f5w6fw6q 5403 12 for for IN cord-006870-f5w6fw6q 5403 13 patients patient NNS cord-006870-f5w6fw6q 5403 14 who who WP cord-006870-f5w6fw6q 5403 15 require require VBP cord-006870-f5w6fw6q 5403 16 active active JJ cord-006870-f5w6fw6q 5403 17 temperature temperature NN cord-006870-f5w6fw6q 5403 18 management management NN cord-006870-f5w6fw6q 5403 19 for for IN cord-006870-f5w6fw6q 5403 20 72 72 CD cord-006870-f5w6fw6q 5403 21 or or CC cord-006870-f5w6fw6q 5403 22 more more JJR cord-006870-f5w6fw6q 5403 23 hours hour NNS cord-006870-f5w6fw6q 5403 24 . . . cord-006870-f5w6fw6q 5404 1 The the DT cord-006870-f5w6fw6q 5404 2 role role NN cord-006870-f5w6fw6q 5404 3 of of IN cord-006870-f5w6fw6q 5404 4 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5404 5 temperature temperature NN cord-006870-f5w6fw6q 5404 6 management management NN cord-006870-f5w6fw6q 5404 7 ( ( -LRB- cord-006870-f5w6fw6q 5404 8 TTM TTM NNP cord-006870-f5w6fw6q 5404 9 ) ) -RRB- cord-006870-f5w6fw6q 5404 10 in in IN cord-006870-f5w6fw6q 5404 11 neurocritical neurocritical NNP cord-006870-f5w6fw6q 5404 12 care care NN cord-006870-f5w6fw6q 5404 13 is be VBZ cord-006870-f5w6fw6q 5404 14 uncertain uncertain JJ cord-006870-f5w6fw6q 5404 15 . . . cord-006870-f5w6fw6q 5405 1 One one CD cord-006870-f5w6fw6q 5405 2 question question NN cord-006870-f5w6fw6q 5405 3 that that WDT cord-006870-f5w6fw6q 5405 4 has have VBZ cord-006870-f5w6fw6q 5405 5 been be VBN cord-006870-f5w6fw6q 5405 6 inadequately inadequately RB cord-006870-f5w6fw6q 5405 7 addressed address VBN cord-006870-f5w6fw6q 5405 8 is be VBZ cord-006870-f5w6fw6q 5405 9 the the DT cord-006870-f5w6fw6q 5405 10 diversity diversity NN cord-006870-f5w6fw6q 5405 11 of of IN cord-006870-f5w6fw6q 5405 12 practice practice NN cord-006870-f5w6fw6q 5405 13 across across IN cord-006870-f5w6fw6q 5405 14 multiple multiple JJ cord-006870-f5w6fw6q 5405 15 neurocritical neurocritical JJ cord-006870-f5w6fw6q 5405 16 care care NN cord-006870-f5w6fw6q 5405 17 units unit NNS cord-006870-f5w6fw6q 5405 18 ( ( -LRB- cord-006870-f5w6fw6q 5405 19 NCCU NCCU NNP cord-006870-f5w6fw6q 5405 20 ) ) -RRB- cord-006870-f5w6fw6q 5405 21 throughout throughout IN cord-006870-f5w6fw6q 5405 22 the the DT cord-006870-f5w6fw6q 5405 23 world world NN cord-006870-f5w6fw6q 5405 24 . . . cord-006870-f5w6fw6q 5406 1 A a DT cord-006870-f5w6fw6q 5406 2 barrier barrier NN cord-006870-f5w6fw6q 5406 3 to to IN cord-006870-f5w6fw6q 5406 4 understanding understand VBG cord-006870-f5w6fw6q 5406 5 this this DT cord-006870-f5w6fw6q 5406 6 practice practice NN cord-006870-f5w6fw6q 5406 7 variance variance NN cord-006870-f5w6fw6q 5406 8 is be VBZ cord-006870-f5w6fw6q 5406 9 a a DT cord-006870-f5w6fw6q 5406 10 data data NN cord-006870-f5w6fw6q 5406 11 collection collection NN cord-006870-f5w6fw6q 5406 12 method method NN cord-006870-f5w6fw6q 5406 13 that that WDT cord-006870-f5w6fw6q 5406 14 would would MD cord-006870-f5w6fw6q 5406 15 provide provide VB cord-006870-f5w6fw6q 5406 16 adequate adequate JJ cord-006870-f5w6fw6q 5406 17 understanding understanding NN cord-006870-f5w6fw6q 5406 18 of of IN cord-006870-f5w6fw6q 5406 19 how how WRB cord-006870-f5w6fw6q 5406 20 TTM TTM NNP cord-006870-f5w6fw6q 5406 21 is be VBZ cord-006870-f5w6fw6q 5406 22 implemented implement VBN cord-006870-f5w6fw6q 5406 23 in in IN cord-006870-f5w6fw6q 5406 24 various various JJ cord-006870-f5w6fw6q 5406 25 NCCUs nccu NNS cord-006870-f5w6fw6q 5406 26 . . . cord-006870-f5w6fw6q 5407 1 The the DT cord-006870-f5w6fw6q 5407 2 purpose purpose NN cord-006870-f5w6fw6q 5407 3 of of IN cord-006870-f5w6fw6q 5407 4 this this DT cord-006870-f5w6fw6q 5407 5 pilot pilot NN cord-006870-f5w6fw6q 5407 6 study study NN cord-006870-f5w6fw6q 5407 7 is be VBZ cord-006870-f5w6fw6q 5407 8 to to TO cord-006870-f5w6fw6q 5407 9 test test VB cord-006870-f5w6fw6q 5407 10 the the DT cord-006870-f5w6fw6q 5407 11 efficacy efficacy NN cord-006870-f5w6fw6q 5407 12 of of IN cord-006870-f5w6fw6q 5407 13 a a DT cord-006870-f5w6fw6q 5407 14 data data NN cord-006870-f5w6fw6q 5407 15 collection collection NN cord-006870-f5w6fw6q 5407 16 method method NN cord-006870-f5w6fw6q 5407 17 that that WDT cord-006870-f5w6fw6q 5407 18 would would MD cord-006870-f5w6fw6q 5407 19 provide provide VB cord-006870-f5w6fw6q 5407 20 unitlevel unitlevel JJ cord-006870-f5w6fw6q 5407 21 data datum NNS cord-006870-f5w6fw6q 5407 22 on on IN cord-006870-f5w6fw6q 5407 23 TTM TTM NNP cord-006870-f5w6fw6q 5407 24 practice practice NN cord-006870-f5w6fw6q 5407 25 . . . cord-006870-f5w6fw6q 5408 1 The the DT cord-006870-f5w6fw6q 5408 2 design design NN cord-006870-f5w6fw6q 5408 3 of of IN cord-006870-f5w6fw6q 5408 4 this this DT cord-006870-f5w6fw6q 5408 5 study study NN cord-006870-f5w6fw6q 5408 6 was be VBD cord-006870-f5w6fw6q 5408 7 prospective prospective JJ cord-006870-f5w6fw6q 5408 8 , , , cord-006870-f5w6fw6q 5408 9 observational observational JJ cord-006870-f5w6fw6q 5408 10 , , , cord-006870-f5w6fw6q 5408 11 and and CC cord-006870-f5w6fw6q 5408 12 cross cross JJ cord-006870-f5w6fw6q 5408 13 - - JJ cord-006870-f5w6fw6q 5408 14 sectional sectional JJ cord-006870-f5w6fw6q 5408 15 study study NN cord-006870-f5w6fw6q 5408 16 using use VBG cord-006870-f5w6fw6q 5408 17 quality quality NN cord-006870-f5w6fw6q 5408 18 assurance assurance NN cord-006870-f5w6fw6q 5408 19 methodology methodology NN cord-006870-f5w6fw6q 5408 20 . . . cord-006870-f5w6fw6q 5409 1 The the DT cord-006870-f5w6fw6q 5409 2 study study NN cord-006870-f5w6fw6q 5409 3 received receive VBD cord-006870-f5w6fw6q 5409 4 Institutional Institutional NNP cord-006870-f5w6fw6q 5409 5 Review Review NNP cord-006870-f5w6fw6q 5409 6 Board Board NNP cord-006870-f5w6fw6q 5409 7 approval approval NN cord-006870-f5w6fw6q 5409 8 . . . cord-006870-f5w6fw6q 5410 1 To to TO cord-006870-f5w6fw6q 5410 2 reduce reduce VB cord-006870-f5w6fw6q 5410 3 the the DT cord-006870-f5w6fw6q 5410 4 risk risk NN cord-006870-f5w6fw6q 5410 5 of of IN cord-006870-f5w6fw6q 5410 6 loss loss NN cord-006870-f5w6fw6q 5410 7 of of IN cord-006870-f5w6fw6q 5410 8 confidentiality confidentiality NN cord-006870-f5w6fw6q 5410 9 and and CC cord-006870-f5w6fw6q 5410 10 promote promote VB cord-006870-f5w6fw6q 5410 11 privacy privacy NN cord-006870-f5w6fw6q 5410 12 , , , cord-006870-f5w6fw6q 5410 13 individual individual JJ cord-006870-f5w6fw6q 5410 14 patients patient NNS cord-006870-f5w6fw6q 5410 15 were be VBD cord-006870-f5w6fw6q 5410 16 not not RB cord-006870-f5w6fw6q 5410 17 consented consent VBN cord-006870-f5w6fw6q 5410 18 . . . cord-006870-f5w6fw6q 5411 1 Data datum NNS cord-006870-f5w6fw6q 5411 2 on on IN cord-006870-f5w6fw6q 5411 3 temperature temperature NN cord-006870-f5w6fw6q 5411 4 management management NN cord-006870-f5w6fw6q 5411 5 was be VBD cord-006870-f5w6fw6q 5411 6 collected collect VBN cord-006870-f5w6fw6q 5411 7 each each DT cord-006870-f5w6fw6q 5411 8 day day NN cord-006870-f5w6fw6q 5411 9 for for IN cord-006870-f5w6fw6q 5411 10 90 90 CD cord-006870-f5w6fw6q 5411 11 consecutive consecutive JJ cord-006870-f5w6fw6q 5411 12 days day NNS cord-006870-f5w6fw6q 5411 13 . . . cord-006870-f5w6fw6q 5412 1 Completed complete VBN cord-006870-f5w6fw6q 5412 2 data datum NNS cord-006870-f5w6fw6q 5412 3 was be VBD cord-006870-f5w6fw6q 5412 4 available available JJ cord-006870-f5w6fw6q 5412 5 for for IN cord-006870-f5w6fw6q 5412 6 90 90 CD cord-006870-f5w6fw6q 5412 7 days day NNS cord-006870-f5w6fw6q 5412 8 . . . cord-006870-f5w6fw6q 5413 1 Mean mean JJ cord-006870-f5w6fw6q 5413 2 daily daily JJ cord-006870-f5w6fw6q 5413 3 census census NN cord-006870-f5w6fw6q 5413 4 of of IN cord-006870-f5w6fw6q 5413 5 15 15 CD cord-006870-f5w6fw6q 5413 6 patients patient NNS cord-006870-f5w6fw6q 5413 7 included include VBD cord-006870-f5w6fw6q 5413 8 the the DT cord-006870-f5w6fw6q 5413 9 following following JJ cord-006870-f5w6fw6q 5413 10 mean mean JJ cord-006870-f5w6fw6q 5413 11 number number NN cord-006870-f5w6fw6q 5413 12 of of IN cord-006870-f5w6fw6q 5413 13 patients patient NNS cord-006870-f5w6fw6q 5413 14 with with IN cord-006870-f5w6fw6q 5413 15 SAH SAH NNP cord-006870-f5w6fw6q 5413 16 ( ( -LRB- cord-006870-f5w6fw6q 5413 17 2 2 CD cord-006870-f5w6fw6q 5413 18 ) ) -RRB- cord-006870-f5w6fw6q 5413 19 , , , cord-006870-f5w6fw6q 5413 20 ICH ICH NNP cord-006870-f5w6fw6q 5413 21 ( ( -LRB- cord-006870-f5w6fw6q 5413 22 1 1 CD cord-006870-f5w6fw6q 5413 23 ) ) -RRB- cord-006870-f5w6fw6q 5413 24 , , , cord-006870-f5w6fw6q 5413 25 ischemic ischemic JJ cord-006870-f5w6fw6q 5413 26 stroke stroke NN cord-006870-f5w6fw6q 5413 27 ( ( -LRB- cord-006870-f5w6fw6q 5413 28 2 2 CD cord-006870-f5w6fw6q 5413 29 ) ) -RRB- cord-006870-f5w6fw6q 5413 30 and and CC cord-006870-f5w6fw6q 5413 31 other other JJ cord-006870-f5w6fw6q 5413 32 ( ( -LRB- cord-006870-f5w6fw6q 5413 33 9 9 CD cord-006870-f5w6fw6q 5413 34 ) ) -RRB- cord-006870-f5w6fw6q 5413 35 . . . cord-006870-f5w6fw6q 5414 1 Of of IN cord-006870-f5w6fw6q 5414 2 those those DT cord-006870-f5w6fw6q 5414 3 , , , cord-006870-f5w6fw6q 5414 4 TTM TTM NNP cord-006870-f5w6fw6q 5414 5 was be VBD cord-006870-f5w6fw6q 5414 6 provided provide VBN cord-006870-f5w6fw6q 5414 7 to to IN cord-006870-f5w6fw6q 5414 8 at at RB cord-006870-f5w6fw6q 5414 9 least least RBS cord-006870-f5w6fw6q 5414 10 one one CD cord-006870-f5w6fw6q 5414 11 patient patient NN cord-006870-f5w6fw6q 5414 12 during during IN cord-006870-f5w6fw6q 5414 13 40 40 CD cord-006870-f5w6fw6q 5414 14 of of IN cord-006870-f5w6fw6q 5414 15 90 90 CD cord-006870-f5w6fw6q 5414 16 days day NNS cord-006870-f5w6fw6q 5414 17 ( ( -LRB- cord-006870-f5w6fw6q 5414 18 44.4 44.4 CD cord-006870-f5w6fw6q 5414 19 % % NN cord-006870-f5w6fw6q 5414 20 ) ) -RRB- cord-006870-f5w6fw6q 5414 21 . . . cord-006870-f5w6fw6q 5415 1 The the DT cord-006870-f5w6fw6q 5415 2 most most RBS cord-006870-f5w6fw6q 5415 3 common common JJ cord-006870-f5w6fw6q 5415 4 TTM TTM NNP cord-006870-f5w6fw6q 5415 5 method method NN cord-006870-f5w6fw6q 5415 6 ( ( -LRB- cord-006870-f5w6fw6q 5415 7 Tylenol Tylenol NNP cord-006870-f5w6fw6q 5415 8 ) ) -RRB- cord-006870-f5w6fw6q 5415 9 was be VBD cord-006870-f5w6fw6q 5415 10 used use VBN cord-006870-f5w6fw6q 5415 11 on on IN cord-006870-f5w6fw6q 5415 12 112 112 CD cord-006870-f5w6fw6q 5415 13 patient patient JJ cord-006870-f5w6fw6q 5415 14 days day NNS cord-006870-f5w6fw6q 5415 15 ; ; : cord-006870-f5w6fw6q 5415 16 surface surface NN cord-006870-f5w6fw6q 5415 17 cooling cooling NN cord-006870-f5w6fw6q 5415 18 was be VBD cord-006870-f5w6fw6q 5415 19 used use VBN cord-006870-f5w6fw6q 5415 20 on on IN cord-006870-f5w6fw6q 5415 21 53 53 CD cord-006870-f5w6fw6q 5415 22 patient patient JJ cord-006870-f5w6fw6q 5415 23 days day NNS cord-006870-f5w6fw6q 5415 24 . . . cord-006870-f5w6fw6q 5416 1 TTM TTM NNP cord-006870-f5w6fw6q 5416 2 was be VBD cord-006870-f5w6fw6q 5416 3 initiated initiate VBN cord-006870-f5w6fw6q 5416 4 for for IN cord-006870-f5w6fw6q 5416 5 fever fever NN cord-006870-f5w6fw6q 5416 6 management management NN cord-006870-f5w6fw6q 5416 7 ( ( -LRB- cord-006870-f5w6fw6q 5416 8 109 109 CD cord-006870-f5w6fw6q 5416 9 patient patient JJ cord-006870-f5w6fw6q 5416 10 days day NNS cord-006870-f5w6fw6q 5416 11 ) ) -RRB- cord-006870-f5w6fw6q 5416 12 and and CC cord-006870-f5w6fw6q 5416 13 normothermia normothermia NN cord-006870-f5w6fw6q 5416 14 ( ( -LRB- cord-006870-f5w6fw6q 5416 15 11 11 CD cord-006870-f5w6fw6q 5416 16 patient patient JJ cord-006870-f5w6fw6q 5416 17 days day NNS cord-006870-f5w6fw6q 5416 18 ) ) -RRB- cord-006870-f5w6fw6q 5416 19 . . . cord-006870-f5w6fw6q 5417 1 The the DT cord-006870-f5w6fw6q 5417 2 most most RBS cord-006870-f5w6fw6q 5417 3 common common JJ cord-006870-f5w6fw6q 5417 4 associated associate VBN cord-006870-f5w6fw6q 5417 5 complication complication NN cord-006870-f5w6fw6q 5417 6 was be VBD cord-006870-f5w6fw6q 5417 7 hypocalcemia hypocalcemia NN cord-006870-f5w6fw6q 5417 8 ( ( -LRB- cord-006870-f5w6fw6q 5417 9 19 19 CD cord-006870-f5w6fw6q 5417 10 ) ) -RRB- cord-006870-f5w6fw6q 5417 11 and and CC cord-006870-f5w6fw6q 5417 12 hypokalemia hypokalemia NN cord-006870-f5w6fw6q 5417 13 ( ( -LRB- cord-006870-f5w6fw6q 5417 14 5 5 CD cord-006870-f5w6fw6q 5417 15 ) ) -RRB- cord-006870-f5w6fw6q 5417 16 . . . cord-006870-f5w6fw6q 5418 1 The the DT cord-006870-f5w6fw6q 5418 2 data datum NNS cord-006870-f5w6fw6q 5418 3 collection collection NN cord-006870-f5w6fw6q 5418 4 form form NN cord-006870-f5w6fw6q 5418 5 was be VBD cord-006870-f5w6fw6q 5418 6 easily easily RB cord-006870-f5w6fw6q 5418 7 and and CC cord-006870-f5w6fw6q 5418 8 quickly quickly RB cord-006870-f5w6fw6q 5418 9 filled fill VBN cord-006870-f5w6fw6q 5418 10 completed complete VBN cord-006870-f5w6fw6q 5418 11 on on IN cord-006870-f5w6fw6q 5418 12 a a DT cord-006870-f5w6fw6q 5418 13 daily daily JJ cord-006870-f5w6fw6q 5418 14 basis basis NN cord-006870-f5w6fw6q 5418 15 , , , cord-006870-f5w6fw6q 5418 16 but but CC cord-006870-f5w6fw6q 5418 17 provides provide VBZ cord-006870-f5w6fw6q 5418 18 limited limited JJ cord-006870-f5w6fw6q 5418 19 data datum NNS cord-006870-f5w6fw6q 5418 20 . . . cord-006870-f5w6fw6q 5419 1 Although although IN cord-006870-f5w6fw6q 5419 2 the the DT cord-006870-f5w6fw6q 5419 3 form form NN cord-006870-f5w6fw6q 5419 4 captured capture VBD cord-006870-f5w6fw6q 5419 5 a a DT cord-006870-f5w6fw6q 5419 6 significant significant JJ cord-006870-f5w6fw6q 5419 7 number number NN cord-006870-f5w6fw6q 5419 8 of of IN cord-006870-f5w6fw6q 5419 9 events event NNS cord-006870-f5w6fw6q 5419 10 surrounding surround VBG cord-006870-f5w6fw6q 5419 11 the the DT cord-006870-f5w6fw6q 5419 12 use use NN cord-006870-f5w6fw6q 5419 13 of of IN cord-006870-f5w6fw6q 5419 14 TTM TTM NNP cord-006870-f5w6fw6q 5419 15 , , , cord-006870-f5w6fw6q 5419 16 the the DT cord-006870-f5w6fw6q 5419 17 primary primary JJ cord-006870-f5w6fw6q 5419 18 limitation limitation NN cord-006870-f5w6fw6q 5419 19 noted note VBD cord-006870-f5w6fw6q 5419 20 is be VBZ cord-006870-f5w6fw6q 5419 21 the the DT cord-006870-f5w6fw6q 5419 22 inability inability NN cord-006870-f5w6fw6q 5419 23 to to TO cord-006870-f5w6fw6q 5419 24 link link VB cord-006870-f5w6fw6q 5419 25 specific specific JJ cord-006870-f5w6fw6q 5419 26 events event NNS cord-006870-f5w6fw6q 5419 27 ( ( -LRB- cord-006870-f5w6fw6q 5419 28 e.g. e.g. RB cord-006870-f5w6fw6q 5419 29 , , , cord-006870-f5w6fw6q 5419 30 hypokalemia hypokalemia NN cord-006870-f5w6fw6q 5419 31 ) ) -RRB- cord-006870-f5w6fw6q 5419 32 to to IN cord-006870-f5w6fw6q 5419 33 specific specific JJ cord-006870-f5w6fw6q 5419 34 patients patient NNS cord-006870-f5w6fw6q 5419 35 or or CC cord-006870-f5w6fw6q 5419 36 diagnoses diagnosis NNS cord-006870-f5w6fw6q 5419 37 . . . cord-006870-f5w6fw6q 5420 1 This this DT cord-006870-f5w6fw6q 5420 2 pilot pilot NN cord-006870-f5w6fw6q 5420 3 study study NN cord-006870-f5w6fw6q 5420 4 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 5420 5 the the DT cord-006870-f5w6fw6q 5420 6 efficacy efficacy NN cord-006870-f5w6fw6q 5420 7 of of IN cord-006870-f5w6fw6q 5420 8 data datum NNS cord-006870-f5w6fw6q 5420 9 capture capture NN cord-006870-f5w6fw6q 5420 10 and and CC cord-006870-f5w6fw6q 5420 11 provides provide VBZ cord-006870-f5w6fw6q 5420 12 insight insight NN cord-006870-f5w6fw6q 5420 13 towards towards IN cord-006870-f5w6fw6q 5420 14 refining refine VBG cord-006870-f5w6fw6q 5420 15 a a DT cord-006870-f5w6fw6q 5420 16 prospective prospective JJ cord-006870-f5w6fw6q 5420 17 observational observational JJ cord-006870-f5w6fw6q 5420 18 study study NN cord-006870-f5w6fw6q 5420 19 to to TO cord-006870-f5w6fw6q 5420 20 describe describe VB cord-006870-f5w6fw6q 5420 21 TTM TTM NNP cord-006870-f5w6fw6q 5420 22 practice practice NN cord-006870-f5w6fw6q 5420 23 . . . cord-006870-f5w6fw6q 5421 1 Brainstem Brainstem NNP cord-006870-f5w6fw6q 5421 2 tumors tumor NNS cord-006870-f5w6fw6q 5421 3 are be VBP cord-006870-f5w6fw6q 5421 4 exceedingly exceedingly RB cord-006870-f5w6fw6q 5421 5 dangerous dangerous JJ cord-006870-f5w6fw6q 5421 6 due due IN cord-006870-f5w6fw6q 5421 7 to to IN cord-006870-f5w6fw6q 5421 8 its -PRON- PRP$ cord-006870-f5w6fw6q 5421 9 proximity proximity NN cord-006870-f5w6fw6q 5421 10 to to IN cord-006870-f5w6fw6q 5421 11 the the DT cord-006870-f5w6fw6q 5421 12 structures structure NNS cord-006870-f5w6fw6q 5421 13 responsible responsible JJ cord-006870-f5w6fw6q 5421 14 for for IN cord-006870-f5w6fw6q 5421 15 basic basic JJ cord-006870-f5w6fw6q 5421 16 human human JJ cord-006870-f5w6fw6q 5421 17 survival survival NN cord-006870-f5w6fw6q 5421 18 in in IN cord-006870-f5w6fw6q 5421 19 the the DT cord-006870-f5w6fw6q 5421 20 neurocritical neurocritical JJ cord-006870-f5w6fw6q 5421 21 care care NN cord-006870-f5w6fw6q 5421 22 setting setting NN cord-006870-f5w6fw6q 5421 23 . . . cord-006870-f5w6fw6q 5422 1 These these DT cord-006870-f5w6fw6q 5422 2 lesions lesion NNS cord-006870-f5w6fw6q 5422 3 may may MD cord-006870-f5w6fw6q 5422 4 cause cause VB cord-006870-f5w6fw6q 5422 5 autonomic autonomic JJ cord-006870-f5w6fw6q 5422 6 dysregulation dysregulation NN cord-006870-f5w6fw6q 5422 7 . . . cord-006870-f5w6fw6q 5423 1 We -PRON- PRP cord-006870-f5w6fw6q 5423 2 report report VBP cord-006870-f5w6fw6q 5423 3 on on IN cord-006870-f5w6fw6q 5423 4 a a DT cord-006870-f5w6fw6q 5423 5 rare rare JJ cord-006870-f5w6fw6q 5423 6 case case NN cord-006870-f5w6fw6q 5423 7 of of IN cord-006870-f5w6fw6q 5423 8 a a DT cord-006870-f5w6fw6q 5423 9 female female NN cord-006870-f5w6fw6q 5423 10 with with IN cord-006870-f5w6fw6q 5423 11 a a DT cord-006870-f5w6fw6q 5423 12 past past JJ cord-006870-f5w6fw6q 5423 13 surgical surgical JJ cord-006870-f5w6fw6q 5423 14 history history NN cord-006870-f5w6fw6q 5423 15 of of IN cord-006870-f5w6fw6q 5423 16 ventriculoperitoneal ventriculoperitoneal NN cord-006870-f5w6fw6q 5423 17 shunt shunt NN cord-006870-f5w6fw6q 5423 18 with with IN cord-006870-f5w6fw6q 5423 19 a a DT cord-006870-f5w6fw6q 5423 20 brainstem brainstem NN cord-006870-f5w6fw6q 5423 21 mass mass NN cord-006870-f5w6fw6q 5423 22 of of IN cord-006870-f5w6fw6q 5423 23 Müllerian müllerian JJ cord-006870-f5w6fw6q 5423 24 type type NN cord-006870-f5w6fw6q 5423 25 epithelial epithelial JJ cord-006870-f5w6fw6q 5423 26 tissue tissue NN cord-006870-f5w6fw6q 5423 27 . . . cord-006870-f5w6fw6q 5424 1 Methods method NNS cord-006870-f5w6fw6q 5424 2 38 38 CD cord-006870-f5w6fw6q 5424 3 year year NN cord-006870-f5w6fw6q 5424 4 old old JJ cord-006870-f5w6fw6q 5424 5 Caucasian caucasian JJ cord-006870-f5w6fw6q 5424 6 female female NN cord-006870-f5w6fw6q 5424 7 presented present VBN cord-006870-f5w6fw6q 5424 8 to to IN cord-006870-f5w6fw6q 5424 9 our -PRON- PRP$ cord-006870-f5w6fw6q 5424 10 hospital hospital NN cord-006870-f5w6fw6q 5424 11 status status NN cord-006870-f5w6fw6q 5424 12 - - HYPH cord-006870-f5w6fw6q 5424 13 post post NN cord-006870-f5w6fw6q 5424 14 fall fall NN cord-006870-f5w6fw6q 5424 15 after after IN cord-006870-f5w6fw6q 5424 16 episodes episode NNS cord-006870-f5w6fw6q 5424 17 of of IN cord-006870-f5w6fw6q 5424 18 lightheadedness lightheadedness NN cord-006870-f5w6fw6q 5424 19 , , , cord-006870-f5w6fw6q 5424 20 as as RB cord-006870-f5w6fw6q 5424 21 well well RB cord-006870-f5w6fw6q 5424 22 as as IN cord-006870-f5w6fw6q 5424 23 , , , cord-006870-f5w6fw6q 5424 24 episodes episode NNS cord-006870-f5w6fw6q 5424 25 of of IN cord-006870-f5w6fw6q 5424 26 decreased decrease VBN cord-006870-f5w6fw6q 5424 27 respirations respiration NNS cord-006870-f5w6fw6q 5424 28 in in IN cord-006870-f5w6fw6q 5424 29 her -PRON- PRP$ cord-006870-f5w6fw6q 5424 30 sleep sleep NN cord-006870-f5w6fw6q 5424 31 . . . cord-006870-f5w6fw6q 5425 1 MRI MRI NNP cord-006870-f5w6fw6q 5425 2 showed show VBD cord-006870-f5w6fw6q 5425 3 a a DT cord-006870-f5w6fw6q 5425 4 medullary medullary JJ cord-006870-f5w6fw6q 5425 5 contrast contrast NN cord-006870-f5w6fw6q 5425 6 enhancing enhance VBG cord-006870-f5w6fw6q 5425 7 mass mass NN cord-006870-f5w6fw6q 5425 8 with with IN cord-006870-f5w6fw6q 5425 9 calcifications calcification NNS cord-006870-f5w6fw6q 5425 10 measuring measure VBG cord-006870-f5w6fw6q 5425 11 2.8 2.8 CD cord-006870-f5w6fw6q 5425 12 x x SYM cord-006870-f5w6fw6q 5425 13 2.7 2.7 CD cord-006870-f5w6fw6q 5425 14 x x SYM cord-006870-f5w6fw6q 5425 15 1.5 1.5 CD cord-006870-f5w6fw6q 5425 16 cm cm NNS cord-006870-f5w6fw6q 5425 17 and and CC cord-006870-f5w6fw6q 5425 18 a a DT cord-006870-f5w6fw6q 5425 19 small small JJ cord-006870-f5w6fw6q 5425 20 calcified calcified JJ cord-006870-f5w6fw6q 5425 21 lesion lesion NN cord-006870-f5w6fw6q 5425 22 in in IN cord-006870-f5w6fw6q 5425 23 the the DT cord-006870-f5w6fw6q 5425 24 right right JJ cord-006870-f5w6fw6q 5425 25 lateral lateral JJ cord-006870-f5w6fw6q 5425 26 ventricle ventricle NN cord-006870-f5w6fw6q 5425 27 . . . cord-006870-f5w6fw6q 5426 1 Suboccipital suboccipital JJ cord-006870-f5w6fw6q 5426 2 craniectomy craniectomy NN cord-006870-f5w6fw6q 5426 3 for for IN cord-006870-f5w6fw6q 5426 4 biopsy biopsy NN cord-006870-f5w6fw6q 5426 5 and and CC cord-006870-f5w6fw6q 5426 6 decompression decompression NN cord-006870-f5w6fw6q 5426 7 was be VBD cord-006870-f5w6fw6q 5426 8 performed perform VBN cord-006870-f5w6fw6q 5426 9 . . . cord-006870-f5w6fw6q 5427 1 Intraoperatively Intraoperatively NNP cord-006870-f5w6fw6q 5427 2 , , , cord-006870-f5w6fw6q 5427 3 the the DT cord-006870-f5w6fw6q 5427 4 heart heart NN cord-006870-f5w6fw6q 5427 5 rate rate NN cord-006870-f5w6fw6q 5427 6 and and CC cord-006870-f5w6fw6q 5427 7 blood blood NN cord-006870-f5w6fw6q 5427 8 pressure pressure NN cord-006870-f5w6fw6q 5427 9 dropped drop VBD cord-006870-f5w6fw6q 5427 10 transiently transiently RB cord-006870-f5w6fw6q 5427 11 due due IN cord-006870-f5w6fw6q 5427 12 to to IN cord-006870-f5w6fw6q 5427 13 the the DT cord-006870-f5w6fw6q 5427 14 mass mass NN cord-006870-f5w6fw6q 5427 15 being be VBG cord-006870-f5w6fw6q 5427 16 firmly firmly RB cord-006870-f5w6fw6q 5427 17 adhered adhere VBN cord-006870-f5w6fw6q 5427 18 with with IN cord-006870-f5w6fw6q 5427 19 calcification calcification NN cord-006870-f5w6fw6q 5427 20 to to IN cord-006870-f5w6fw6q 5427 21 the the DT cord-006870-f5w6fw6q 5427 22 medulla medulla NN cord-006870-f5w6fw6q 5427 23 . . . cord-006870-f5w6fw6q 5428 1 The the DT cord-006870-f5w6fw6q 5428 2 neuropathologist neuropathologist NN cord-006870-f5w6fw6q 5428 3 diagnosed diagnose VBD cord-006870-f5w6fw6q 5428 4 the the DT cord-006870-f5w6fw6q 5428 5 tissue tissue NN cord-006870-f5w6fw6q 5428 6 as as IN cord-006870-f5w6fw6q 5428 7 Mullerian mullerian JJ cord-006870-f5w6fw6q 5428 8 Type type NN cord-006870-f5w6fw6q 5428 9 Epithelium epithelium NN cord-006870-f5w6fw6q 5428 10 with with IN cord-006870-f5w6fw6q 5428 11 estrogen estrogen NN cord-006870-f5w6fw6q 5428 12 receptors receptor NNS cord-006870-f5w6fw6q 5428 13 . . . cord-006870-f5w6fw6q 5429 1 Post post VB cord-006870-f5w6fw6q 5429 2 - - JJ cord-006870-f5w6fw6q 5429 3 operatively operatively RB cord-006870-f5w6fw6q 5429 4 , , , cord-006870-f5w6fw6q 5429 5 our -PRON- PRP$ cord-006870-f5w6fw6q 5429 6 patient patient NN cord-006870-f5w6fw6q 5429 7 encountered encounter VBD cord-006870-f5w6fw6q 5429 8 several several JJ cord-006870-f5w6fw6q 5429 9 instances instance NNS cord-006870-f5w6fw6q 5429 10 of of IN cord-006870-f5w6fw6q 5429 11 cardiac cardiac JJ cord-006870-f5w6fw6q 5429 12 pauses pause NNS cord-006870-f5w6fw6q 5429 13 on on IN cord-006870-f5w6fw6q 5429 14 monitoring monitoring NN cord-006870-f5w6fw6q 5429 15 that that WDT cord-006870-f5w6fw6q 5429 16 required require VBD cord-006870-f5w6fw6q 5429 17 the the DT cord-006870-f5w6fw6q 5429 18 need need NN cord-006870-f5w6fw6q 5429 19 for for IN cord-006870-f5w6fw6q 5429 20 cardiology cardiology NN cord-006870-f5w6fw6q 5429 21 to to TO cord-006870-f5w6fw6q 5429 22 place place VB cord-006870-f5w6fw6q 5429 23 a a DT cord-006870-f5w6fw6q 5429 24 permanent permanent JJ cord-006870-f5w6fw6q 5429 25 pacemaker pacemaker NN cord-006870-f5w6fw6q 5429 26 . . . cord-006870-f5w6fw6q 5430 1 The the DT cord-006870-f5w6fw6q 5430 2 above above JJ cord-006870-f5w6fw6q 5430 3 is be VBZ cord-006870-f5w6fw6q 5430 4 a a DT cord-006870-f5w6fw6q 5430 5 rare rare JJ cord-006870-f5w6fw6q 5430 6 case case NN cord-006870-f5w6fw6q 5430 7 of of IN cord-006870-f5w6fw6q 5430 8 a a DT cord-006870-f5w6fw6q 5430 9 calcified calcified JJ cord-006870-f5w6fw6q 5430 10 heterogeneously heterogeneously NN cord-006870-f5w6fw6q 5430 11 contrast contrast NN cord-006870-f5w6fw6q 5430 12 enhancing enhance VBG cord-006870-f5w6fw6q 5430 13 brainstem brainstem NNP cord-006870-f5w6fw6q 5430 14 mass mass NN cord-006870-f5w6fw6q 5430 15 that that WDT cord-006870-f5w6fw6q 5430 16 underwent undergo VBD cord-006870-f5w6fw6q 5430 17 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 5430 18 biopsy biopsy NN cord-006870-f5w6fw6q 5430 19 . . . cord-006870-f5w6fw6q 5431 1 Histopathology Histopathology NNP cord-006870-f5w6fw6q 5431 2 results result NNS cord-006870-f5w6fw6q 5431 3 indicated indicate VBD cord-006870-f5w6fw6q 5431 4 Müllerian müllerian JJ cord-006870-f5w6fw6q 5431 5 type type NN cord-006870-f5w6fw6q 5431 6 epithelial epithelial JJ cord-006870-f5w6fw6q 5431 7 tissue tissue NN cord-006870-f5w6fw6q 5431 8 which which WDT cord-006870-f5w6fw6q 5431 9 is be VBZ cord-006870-f5w6fw6q 5431 10 tissue tissue NN cord-006870-f5w6fw6q 5431 11 that that WDT cord-006870-f5w6fw6q 5431 12 gives give VBZ cord-006870-f5w6fw6q 5431 13 rise rise NN cord-006870-f5w6fw6q 5431 14 to to IN cord-006870-f5w6fw6q 5431 15 female female JJ cord-006870-f5w6fw6q 5431 16 reproductive reproductive JJ cord-006870-f5w6fw6q 5431 17 organs organ NNS cord-006870-f5w6fw6q 5431 18 . . . cord-006870-f5w6fw6q 5432 1 The the DT cord-006870-f5w6fw6q 5432 2 origin origin NN cord-006870-f5w6fw6q 5432 3 of of IN cord-006870-f5w6fw6q 5432 4 a a DT cord-006870-f5w6fw6q 5432 5 brainstem brainstem NN cord-006870-f5w6fw6q 5432 6 lesion lesion NN cord-006870-f5w6fw6q 5432 7 from from IN cord-006870-f5w6fw6q 5432 8 an an DT cord-006870-f5w6fw6q 5432 9 embryologically embryologically RB cord-006870-f5w6fw6q 5432 10 gynecological gynecological JJ cord-006870-f5w6fw6q 5432 11 site site NN cord-006870-f5w6fw6q 5432 12 could could MD cord-006870-f5w6fw6q 5432 13 be be VB cord-006870-f5w6fw6q 5432 14 speculated speculate VBN cord-006870-f5w6fw6q 5432 15 to to TO cord-006870-f5w6fw6q 5432 16 have have VB cord-006870-f5w6fw6q 5432 17 traveled travel VBN cord-006870-f5w6fw6q 5432 18 retrograde retrograde JJ cord-006870-f5w6fw6q 5432 19 via via IN cord-006870-f5w6fw6q 5432 20 the the DT cord-006870-f5w6fw6q 5432 21 ventriculoperitoneal ventriculoperitoneal NN cord-006870-f5w6fw6q 5432 22 shunt shunt NN cord-006870-f5w6fw6q 5432 23 catheter catheter NN cord-006870-f5w6fw6q 5432 24 . . . cord-006870-f5w6fw6q 5433 1 Patient patient NN cord-006870-f5w6fw6q 5433 2 required require VBD cord-006870-f5w6fw6q 5433 3 postoperative postoperative JJ cord-006870-f5w6fw6q 5433 4 cardiac cardiac JJ cord-006870-f5w6fw6q 5433 5 management management NN cord-006870-f5w6fw6q 5433 6 and and CC cord-006870-f5w6fw6q 5433 7 intervention intervention NN cord-006870-f5w6fw6q 5433 8 with with IN cord-006870-f5w6fw6q 5433 9 a a DT cord-006870-f5w6fw6q 5433 10 pacemaker pacemaker NN cord-006870-f5w6fw6q 5433 11 for for IN cord-006870-f5w6fw6q 5433 12 encroachment encroachment NN cord-006870-f5w6fw6q 5433 13 or or CC cord-006870-f5w6fw6q 5433 14 mechanical mechanical JJ cord-006870-f5w6fw6q 5433 15 conflict conflict NN cord-006870-f5w6fw6q 5433 16 of of IN cord-006870-f5w6fw6q 5433 17 the the DT cord-006870-f5w6fw6q 5433 18 mass mass NN cord-006870-f5w6fw6q 5433 19 onto onto IN cord-006870-f5w6fw6q 5433 20 the the DT cord-006870-f5w6fw6q 5433 21 rostral rostral JJ cord-006870-f5w6fw6q 5433 22 ventrolateral ventrolateral JJ cord-006870-f5w6fw6q 5433 23 medulla medulla NN cord-006870-f5w6fw6q 5433 24 . . . cord-006870-f5w6fw6q 5434 1 Oncology oncology NN cord-006870-f5w6fw6q 5434 2 recommended recommend VBD cord-006870-f5w6fw6q 5434 3 PET PET NNP cord-006870-f5w6fw6q 5434 4 CT CT NNP cord-006870-f5w6fw6q 5434 5 scan scan NN cord-006870-f5w6fw6q 5434 6 and and CC cord-006870-f5w6fw6q 5434 7 further further JJ cord-006870-f5w6fw6q 5434 8 consideration consideration NN cord-006870-f5w6fw6q 5434 9 for for IN cord-006870-f5w6fw6q 5434 10 tamoxifen tamoxifen NN cord-006870-f5w6fw6q 5434 11 chemotherapeutic chemotherapeutic JJ cord-006870-f5w6fw6q 5434 12 regimen regimen NN cord-006870-f5w6fw6q 5434 13 . . . cord-006870-f5w6fw6q 5435 1 This this DT cord-006870-f5w6fw6q 5435 2 case case NN cord-006870-f5w6fw6q 5435 3 is be VBZ cord-006870-f5w6fw6q 5435 4 a a DT cord-006870-f5w6fw6q 5435 5 reaffirmation reaffirmation NN cord-006870-f5w6fw6q 5435 6 of of IN cord-006870-f5w6fw6q 5435 7 the the DT cord-006870-f5w6fw6q 5435 8 importance importance NN cord-006870-f5w6fw6q 5435 9 of of IN cord-006870-f5w6fw6q 5435 10 brain brain NN cord-006870-f5w6fw6q 5435 11 tumor tumor NN cord-006870-f5w6fw6q 5435 12 location location NN cord-006870-f5w6fw6q 5435 13 and and CC cord-006870-f5w6fw6q 5435 14 tissue tissue NN cord-006870-f5w6fw6q 5435 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 5435 16 for for IN cord-006870-f5w6fw6q 5435 17 the the DT cord-006870-f5w6fw6q 5435 18 purpose purpose NN cord-006870-f5w6fw6q 5435 19 of of IN cord-006870-f5w6fw6q 5435 20 adjuvant adjuvant JJ cord-006870-f5w6fw6q 5435 21 treatment treatment NN cord-006870-f5w6fw6q 5435 22 of of IN cord-006870-f5w6fw6q 5435 23 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 5435 24 lesions lesion NNS cord-006870-f5w6fw6q 5435 25 in in IN cord-006870-f5w6fw6q 5435 26 the the DT cord-006870-f5w6fw6q 5435 27 neurocritical neurocritical JJ cord-006870-f5w6fw6q 5435 28 care care NN cord-006870-f5w6fw6q 5435 29 setting setting NN cord-006870-f5w6fw6q 5435 30 . . . cord-006870-f5w6fw6q 5436 1 Tranexamic tranexamic JJ cord-006870-f5w6fw6q 5436 2 acid acid NN cord-006870-f5w6fw6q 5436 3 ( ( -LRB- cord-006870-f5w6fw6q 5436 4 TXA TXA NNP cord-006870-f5w6fw6q 5436 5 ) ) -RRB- cord-006870-f5w6fw6q 5436 6 has have VBZ cord-006870-f5w6fw6q 5436 7 been be VBN cord-006870-f5w6fw6q 5436 8 used use VBN cord-006870-f5w6fw6q 5436 9 off off RP cord-006870-f5w6fw6q 5436 10 label label NN cord-006870-f5w6fw6q 5436 11 in in IN cord-006870-f5w6fw6q 5436 12 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 5436 13 and and CC cord-006870-f5w6fw6q 5436 14 orthopedic orthopedic NN cord-006870-f5w6fw6q 5436 15 surgery surgery NN cord-006870-f5w6fw6q 5436 16 , , , cord-006870-f5w6fw6q 5436 17 as as RB cord-006870-f5w6fw6q 5436 18 well well RB cord-006870-f5w6fw6q 5436 19 as as IN cord-006870-f5w6fw6q 5436 20 in in IN cord-006870-f5w6fw6q 5436 21 trauma trauma NN cord-006870-f5w6fw6q 5436 22 resuscitation resuscitation NN cord-006870-f5w6fw6q 5436 23 . . . cord-006870-f5w6fw6q 5437 1 The the DT cord-006870-f5w6fw6q 5437 2 use use NN cord-006870-f5w6fw6q 5437 3 of of IN cord-006870-f5w6fw6q 5437 4 TXA TXA NNP cord-006870-f5w6fw6q 5437 5 has have VBZ cord-006870-f5w6fw6q 5437 6 increased increase VBN cord-006870-f5w6fw6q 5437 7 since since IN cord-006870-f5w6fw6q 5437 8 the the DT cord-006870-f5w6fw6q 5437 9 publication publication NN cord-006870-f5w6fw6q 5437 10 of of IN cord-006870-f5w6fw6q 5437 11 CRASH-2 CRASH-2 NNP cord-006870-f5w6fw6q 5437 12 ( ( -LRB- cord-006870-f5w6fw6q 5437 13 2010 2010 CD cord-006870-f5w6fw6q 5437 14 ) ) -RRB- cord-006870-f5w6fw6q 5437 15 and and CC cord-006870-f5w6fw6q 5437 16 MATTERs MATTERs NNPS cord-006870-f5w6fw6q 5437 17 ( ( -LRB- cord-006870-f5w6fw6q 5437 18 2012 2012 CD cord-006870-f5w6fw6q 5437 19 ) ) -RRB- cord-006870-f5w6fw6q 5437 20 , , , cord-006870-f5w6fw6q 5437 21 demonstrating demonstrate VBG cord-006870-f5w6fw6q 5437 22 its -PRON- PRP$ cord-006870-f5w6fw6q 5437 23 efficacy efficacy NN cord-006870-f5w6fw6q 5437 24 in in IN cord-006870-f5w6fw6q 5437 25 trauma trauma NN cord-006870-f5w6fw6q 5437 26 patients patient NNS cord-006870-f5w6fw6q 5437 27 to to TO cord-006870-f5w6fw6q 5437 28 reduce reduce VB cord-006870-f5w6fw6q 5437 29 bleeding bleeding NN cord-006870-f5w6fw6q 5437 30 . . . cord-006870-f5w6fw6q 5438 1 There there EX cord-006870-f5w6fw6q 5438 2 remains remain VBZ cord-006870-f5w6fw6q 5438 3 concern concern NN cord-006870-f5w6fw6q 5438 4 about about IN cord-006870-f5w6fw6q 5438 5 the the DT cord-006870-f5w6fw6q 5438 6 thrombotic thrombotic JJ cord-006870-f5w6fw6q 5438 7 risk risk NN cord-006870-f5w6fw6q 5438 8 as as IN cord-006870-f5w6fw6q 5438 9 well well RB cord-006870-f5w6fw6q 5438 10 the the DT cord-006870-f5w6fw6q 5438 11 reduction reduction NN cord-006870-f5w6fw6q 5438 12 in in IN cord-006870-f5w6fw6q 5438 13 the the DT cord-006870-f5w6fw6q 5438 14 seizure seizure NN cord-006870-f5w6fw6q 5438 15 threshold threshold NN cord-006870-f5w6fw6q 5438 16 after after IN cord-006870-f5w6fw6q 5438 17 TXA TXA NNP cord-006870-f5w6fw6q 5438 18 administration administration NN cord-006870-f5w6fw6q 5438 19 . . . cord-006870-f5w6fw6q 5439 1 Case case NN cord-006870-f5w6fw6q 5439 2 Description description NN cord-006870-f5w6fw6q 5439 3 : : : cord-006870-f5w6fw6q 5439 4 We -PRON- PRP cord-006870-f5w6fw6q 5439 5 present present VBP cord-006870-f5w6fw6q 5439 6 a a DT cord-006870-f5w6fw6q 5439 7 case case NN cord-006870-f5w6fw6q 5439 8 of of IN cord-006870-f5w6fw6q 5439 9 a a DT cord-006870-f5w6fw6q 5439 10 25-year 25-year JJ cord-006870-f5w6fw6q 5439 11 - - HYPH cord-006870-f5w6fw6q 5439 12 old old JJ cord-006870-f5w6fw6q 5439 13 female female NN cord-006870-f5w6fw6q 5439 14 admitted admit VBN cord-006870-f5w6fw6q 5439 15 to to IN cord-006870-f5w6fw6q 5439 16 the the DT cord-006870-f5w6fw6q 5439 17 surgical surgical JJ cord-006870-f5w6fw6q 5439 18 ICU ICU NNP cord-006870-f5w6fw6q 5439 19 after after IN cord-006870-f5w6fw6q 5439 20 a a DT cord-006870-f5w6fw6q 5439 21 motor motor NN cord-006870-f5w6fw6q 5439 22 vehicle vehicle NN cord-006870-f5w6fw6q 5439 23 accident accident NN cord-006870-f5w6fw6q 5439 24 with with IN cord-006870-f5w6fw6q 5439 25 multiple multiple JJ cord-006870-f5w6fw6q 5439 26 traumatic traumatic JJ cord-006870-f5w6fw6q 5439 27 pelvic pelvic NN cord-006870-f5w6fw6q 5439 28 and and CC cord-006870-f5w6fw6q 5439 29 extremity extremity NN cord-006870-f5w6fw6q 5439 30 fractures fracture NNS cord-006870-f5w6fw6q 5439 31 and and CC cord-006870-f5w6fw6q 5439 32 soft soft JJ cord-006870-f5w6fw6q 5439 33 tissue tissue NN cord-006870-f5w6fw6q 5439 34 injury injury NN cord-006870-f5w6fw6q 5439 35 . . . cord-006870-f5w6fw6q 5440 1 She -PRON- PRP cord-006870-f5w6fw6q 5440 2 subsequently subsequently RB cord-006870-f5w6fw6q 5440 3 developed develop VBD cord-006870-f5w6fw6q 5440 4 extensive extensive JJ cord-006870-f5w6fw6q 5440 5 arterial arterial JJ cord-006870-f5w6fw6q 5440 6 and and CC cord-006870-f5w6fw6q 5440 7 venous venous JJ cord-006870-f5w6fw6q 5440 8 thromboses thrombose NNS cord-006870-f5w6fw6q 5440 9 with with IN cord-006870-f5w6fw6q 5440 10 bilateral bilateral JJ cord-006870-f5w6fw6q 5440 11 acute acute JJ cord-006870-f5w6fw6q 5440 12 ischemic ischemic JJ cord-006870-f5w6fw6q 5440 13 strokes stroke NNS cord-006870-f5w6fw6q 5440 14 with with IN cord-006870-f5w6fw6q 5440 15 superimposed superimpose VBN cord-006870-f5w6fw6q 5440 16 posterior posterior JJ cord-006870-f5w6fw6q 5440 17 reversible reversible JJ cord-006870-f5w6fw6q 5440 18 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5440 19 syndrome syndrome NN cord-006870-f5w6fw6q 5440 20 after after IN cord-006870-f5w6fw6q 5440 21 TXA TXA NNP cord-006870-f5w6fw6q 5440 22 administration administration NN cord-006870-f5w6fw6q 5440 23 . . . cord-006870-f5w6fw6q 5441 1 A a DT cord-006870-f5w6fw6q 5441 2 second second JJ cord-006870-f5w6fw6q 5441 3 case case NN cord-006870-f5w6fw6q 5441 4 involved involve VBD cord-006870-f5w6fw6q 5441 5 a a DT cord-006870-f5w6fw6q 5441 6 50-year 50-year JJ cord-006870-f5w6fw6q 5441 7 - - HYPH cord-006870-f5w6fw6q 5441 8 old old JJ cord-006870-f5w6fw6q 5441 9 female female NN cord-006870-f5w6fw6q 5441 10 who who WP cord-006870-f5w6fw6q 5441 11 had have VBD cord-006870-f5w6fw6q 5441 12 a a DT cord-006870-f5w6fw6q 5441 13 fall fall NN cord-006870-f5w6fw6q 5441 14 from from IN cord-006870-f5w6fw6q 5441 15 standing stand VBG cord-006870-f5w6fw6q 5441 16 and and CC cord-006870-f5w6fw6q 5441 17 given give VBN cord-006870-f5w6fw6q 5441 18 TXA TXA NNP cord-006870-f5w6fw6q 5441 19 in in IN cord-006870-f5w6fw6q 5441 20 the the DT cord-006870-f5w6fw6q 5441 21 field field NN cord-006870-f5w6fw6q 5441 22 by by IN cord-006870-f5w6fw6q 5441 23 EMS EMS NNP cord-006870-f5w6fw6q 5441 24 . . . cord-006870-f5w6fw6q 5442 1 Shewas Shewas NNP cord-006870-f5w6fw6q 5442 2 admitted admit VBD cord-006870-f5w6fw6q 5442 3 to to IN cord-006870-f5w6fw6q 5442 4 the the DT cord-006870-f5w6fw6q 5442 5 neurocritical neurocritical NNP cord-006870-f5w6fw6q 5442 6 care care NN cord-006870-f5w6fw6q 5442 7 unit unit NN cord-006870-f5w6fw6q 5442 8 with with IN cord-006870-f5w6fw6q 5442 9 status status NN cord-006870-f5w6fw6q 5442 10 epilepticus epilepticus NN cord-006870-f5w6fw6q 5442 11 and and CC cord-006870-f5w6fw6q 5442 12 suffered suffer VBD cord-006870-f5w6fw6q 5442 13 a a DT cord-006870-f5w6fw6q 5442 14 complicated complicated JJ cord-006870-f5w6fw6q 5442 15 course course NN cord-006870-f5w6fw6q 5442 16 with with IN cord-006870-f5w6fw6q 5442 17 cardiogenic cardiogenic JJ cord-006870-f5w6fw6q 5442 18 shock shock NN cord-006870-f5w6fw6q 5442 19 due due IN cord-006870-f5w6fw6q 5442 20 to to IN cord-006870-f5w6fw6q 5442 21 stress stress NN cord-006870-f5w6fw6q 5442 22 induced induce VBN cord-006870-f5w6fw6q 5442 23 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 5442 24 . . . cord-006870-f5w6fw6q 5443 1 Discussion discussion NN cord-006870-f5w6fw6q 5443 2 : : : cord-006870-f5w6fw6q 5444 1 The the DT cord-006870-f5w6fw6q 5444 2 risk risk NN cord-006870-f5w6fw6q 5444 3 - - HYPH cord-006870-f5w6fw6q 5444 4 benefit benefit NN cord-006870-f5w6fw6q 5444 5 balance balance NN cord-006870-f5w6fw6q 5444 6 of of IN cord-006870-f5w6fw6q 5444 7 TXA TXA NNP cord-006870-f5w6fw6q 5444 8 administration administration NN cord-006870-f5w6fw6q 5444 9 is be VBZ cord-006870-f5w6fw6q 5444 10 generally generally RB cord-006870-f5w6fw6q 5444 11 considered consider VBN cord-006870-f5w6fw6q 5444 12 acceptable acceptable JJ cord-006870-f5w6fw6q 5444 13 in in IN cord-006870-f5w6fw6q 5444 14 severe severe JJ cord-006870-f5w6fw6q 5444 15 bleeding bleeding NN cord-006870-f5w6fw6q 5444 16 . . . cord-006870-f5w6fw6q 5445 1 The the DT cord-006870-f5w6fw6q 5445 2 cases case NNS cord-006870-f5w6fw6q 5445 3 presented present VBN cord-006870-f5w6fw6q 5445 4 here here RB cord-006870-f5w6fw6q 5445 5 suggest suggest VBP cord-006870-f5w6fw6q 5445 6 the the DT cord-006870-f5w6fw6q 5445 7 neurological neurological JJ cord-006870-f5w6fw6q 5445 8 risks risk NNS cord-006870-f5w6fw6q 5445 9 of of IN cord-006870-f5w6fw6q 5445 10 TXA TXA NNP cord-006870-f5w6fw6q 5445 11 administration administration NN cord-006870-f5w6fw6q 5445 12 may may MD cord-006870-f5w6fw6q 5445 13 be be VB cord-006870-f5w6fw6q 5445 14 poorly poorly RB cord-006870-f5w6fw6q 5445 15 understood understand VBN cord-006870-f5w6fw6q 5445 16 and and CC cord-006870-f5w6fw6q 5445 17 demonstrate demonstrate VB cord-006870-f5w6fw6q 5445 18 the the DT cord-006870-f5w6fw6q 5445 19 need need NN cord-006870-f5w6fw6q 5445 20 for for IN cord-006870-f5w6fw6q 5445 21 better well JJR cord-006870-f5w6fw6q 5445 22 patient patient NN cord-006870-f5w6fw6q 5445 23 selection selection NN cord-006870-f5w6fw6q 5445 24 and and CC cord-006870-f5w6fw6q 5445 25 heightened heightened JJ cord-006870-f5w6fw6q 5445 26 awareness awareness NN cord-006870-f5w6fw6q 5445 27 for for IN cord-006870-f5w6fw6q 5445 28 early early JJ cord-006870-f5w6fw6q 5445 29 identification identification NN cord-006870-f5w6fw6q 5445 30 and and CC cord-006870-f5w6fw6q 5445 31 management management NN cord-006870-f5w6fw6q 5445 32 of of IN cord-006870-f5w6fw6q 5445 33 complications complication NNS cord-006870-f5w6fw6q 5445 34 given give VBN cord-006870-f5w6fw6q 5445 35 the the DT cord-006870-f5w6fw6q 5445 36 possible possible JJ cord-006870-f5w6fw6q 5445 37 severity severity NN cord-006870-f5w6fw6q 5445 38 of of IN cord-006870-f5w6fw6q 5445 39 neurologic neurologic JJ cord-006870-f5w6fw6q 5445 40 sequelae sequela NNS cord-006870-f5w6fw6q 5445 41 . . . cord-006870-f5w6fw6q 5446 1 Conclusion conclusion NN cord-006870-f5w6fw6q 5446 2 : : : cord-006870-f5w6fw6q 5447 1 TXA TXA NNP cord-006870-f5w6fw6q 5447 2 is be VBZ cord-006870-f5w6fw6q 5447 3 an an DT cord-006870-f5w6fw6q 5447 4 anti anti JJ cord-006870-f5w6fw6q 5447 5 - - JJ cord-006870-f5w6fw6q 5447 6 plasmin plasmin JJ cord-006870-f5w6fw6q 5447 7 drug drug NN cord-006870-f5w6fw6q 5447 8 that that WDT cord-006870-f5w6fw6q 5447 9 is be VBZ cord-006870-f5w6fw6q 5447 10 increasingly increasingly RB cord-006870-f5w6fw6q 5447 11 used use VBN cord-006870-f5w6fw6q 5447 12 in in IN cord-006870-f5w6fw6q 5447 13 the the DT cord-006870-f5w6fw6q 5447 14 areas area NNS cord-006870-f5w6fw6q 5447 15 of of IN cord-006870-f5w6fw6q 5447 16 trauma trauma NN cord-006870-f5w6fw6q 5447 17 and and CC cord-006870-f5w6fw6q 5447 18 postoperative postoperative JJ cord-006870-f5w6fw6q 5447 19 bleeding bleeding NN cord-006870-f5w6fw6q 5447 20 . . . cord-006870-f5w6fw6q 5448 1 We -PRON- PRP cord-006870-f5w6fw6q 5448 2 aim aim VBP cord-006870-f5w6fw6q 5448 3 to to TO cord-006870-f5w6fw6q 5448 4 educate educate VB cord-006870-f5w6fw6q 5448 5 clinicians clinician NNS cord-006870-f5w6fw6q 5448 6 in in IN cord-006870-f5w6fw6q 5448 7 the the DT cord-006870-f5w6fw6q 5448 8 potential potential JJ cord-006870-f5w6fw6q 5448 9 neurological neurological JJ cord-006870-f5w6fw6q 5448 10 complications complication NNS cord-006870-f5w6fw6q 5448 11 that that WDT cord-006870-f5w6fw6q 5448 12 can can MD cord-006870-f5w6fw6q 5448 13 arise arise VB cord-006870-f5w6fw6q 5448 14 with with IN cord-006870-f5w6fw6q 5448 15 its -PRON- PRP$ cord-006870-f5w6fw6q 5448 16 use use NN cord-006870-f5w6fw6q 5448 17 . . . cord-006870-f5w6fw6q 5449 1 Cryptococcus Cryptococcus NNP cord-006870-f5w6fw6q 5449 2 Neoformans Neoformans NNP cord-006870-f5w6fw6q 5449 3 is be VBZ cord-006870-f5w6fw6q 5449 4 normally normally RB cord-006870-f5w6fw6q 5449 5 an an DT cord-006870-f5w6fw6q 5449 6 opportunistic opportunistic JJ cord-006870-f5w6fw6q 5449 7 infection infection NN cord-006870-f5w6fw6q 5449 8 known know VBN cord-006870-f5w6fw6q 5449 9 to to TO cord-006870-f5w6fw6q 5449 10 cause cause VB cord-006870-f5w6fw6q 5449 11 meningoencephalitis meningoencephalitis NNP cord-006870-f5w6fw6q 5449 12 and and CC cord-006870-f5w6fw6q 5449 13 can can MD cord-006870-f5w6fw6q 5449 14 present present VB cord-006870-f5w6fw6q 5449 15 with with IN cord-006870-f5w6fw6q 5449 16 stroke stroke NN cord-006870-f5w6fw6q 5449 17 like like IN cord-006870-f5w6fw6q 5449 18 symptoms symptom NNS cord-006870-f5w6fw6q 5449 19 . . . cord-006870-f5w6fw6q 5450 1 In in IN cord-006870-f5w6fw6q 5450 2 imaging imaging NN cord-006870-f5w6fw6q 5450 3 , , , cord-006870-f5w6fw6q 5450 4 CNS CNS NNP cord-006870-f5w6fw6q 5450 5 vasculitis vasculitis NN cord-006870-f5w6fw6q 5450 6 can can MD cord-006870-f5w6fw6q 5450 7 be be VB cord-006870-f5w6fw6q 5450 8 identified identify VBN cord-006870-f5w6fw6q 5450 9 , , , cord-006870-f5w6fw6q 5450 10 which which WDT cord-006870-f5w6fw6q 5450 11 can can MD cord-006870-f5w6fw6q 5450 12 lead lead VB cord-006870-f5w6fw6q 5450 13 to to IN cord-006870-f5w6fw6q 5450 14 cerebral cerebral JJ cord-006870-f5w6fw6q 5450 15 infarcts infarct NNS cord-006870-f5w6fw6q 5450 16 . . . cord-006870-f5w6fw6q 5451 1 When when WRB cord-006870-f5w6fw6q 5451 2 involved involve VBN cord-006870-f5w6fw6q 5451 3 , , , cord-006870-f5w6fw6q 5451 4 these these DT cord-006870-f5w6fw6q 5451 5 cerebral cerebral JJ cord-006870-f5w6fw6q 5451 6 vessels vessel NNS cord-006870-f5w6fw6q 5451 7 are be VBP cord-006870-f5w6fw6q 5451 8 small small JJ cord-006870-f5w6fw6q 5451 9 sized sized JJ cord-006870-f5w6fw6q 5451 10 leading lead VBG cord-006870-f5w6fw6q 5451 11 to to IN cord-006870-f5w6fw6q 5451 12 lacunar lacunar NNP cord-006870-f5w6fw6q 5451 13 infarcts infarct NNS cord-006870-f5w6fw6q 5451 14 . . . cord-006870-f5w6fw6q 5452 1 We -PRON- PRP cord-006870-f5w6fw6q 5452 2 present present VBP cord-006870-f5w6fw6q 5452 3 a a DT cord-006870-f5w6fw6q 5452 4 case case NN cord-006870-f5w6fw6q 5452 5 that that WDT cord-006870-f5w6fw6q 5452 6 involved involve VBD cord-006870-f5w6fw6q 5452 7 a a DT cord-006870-f5w6fw6q 5452 8 large large JJ cord-006870-f5w6fw6q 5452 9 vessel vessel NN cord-006870-f5w6fw6q 5452 10 territory territory NN cord-006870-f5w6fw6q 5452 11 leading lead VBG cord-006870-f5w6fw6q 5452 12 to to IN cord-006870-f5w6fw6q 5452 13 patient patient JJ cord-006870-f5w6fw6q 5452 14 mortality mortality NN cord-006870-f5w6fw6q 5452 15 . . . cord-006870-f5w6fw6q 5453 1 Initial initial JJ cord-006870-f5w6fw6q 5453 2 treatment treatment NN cord-006870-f5w6fw6q 5453 3 with with IN cord-006870-f5w6fw6q 5453 4 glucocorticoids glucocorticoid NNS cord-006870-f5w6fw6q 5453 5 , , , cord-006870-f5w6fw6q 5453 6 though though IN cord-006870-f5w6fw6q 5453 7 beneficial beneficial JJ cord-006870-f5w6fw6q 5453 8 in in IN cord-006870-f5w6fw6q 5453 9 other other JJ cord-006870-f5w6fw6q 5453 10 meningoencephalitidies meningoencephalitidie NNS cord-006870-f5w6fw6q 5453 11 , , , cord-006870-f5w6fw6q 5453 12 may may MD cord-006870-f5w6fw6q 5453 13 actually actually RB cord-006870-f5w6fw6q 5453 14 be be VB cord-006870-f5w6fw6q 5453 15 harmful harmful JJ cord-006870-f5w6fw6q 5453 16 in in IN cord-006870-f5w6fw6q 5453 17 fungal fungal JJ cord-006870-f5w6fw6q 5453 18 CNS CNS NNP cord-006870-f5w6fw6q 5453 19 infections infection NNS cord-006870-f5w6fw6q 5453 20 . . . cord-006870-f5w6fw6q 5454 1 Case case NN cord-006870-f5w6fw6q 5454 2 : : : cord-006870-f5w6fw6q 5455 1 A a DT cord-006870-f5w6fw6q 5455 2 57 57 CD cord-006870-f5w6fw6q 5455 3 year year NN cord-006870-f5w6fw6q 5455 4 old old JJ cord-006870-f5w6fw6q 5455 5 male male NN cord-006870-f5w6fw6q 5455 6 with with IN cord-006870-f5w6fw6q 5455 7 a a DT cord-006870-f5w6fw6q 5455 8 presents present NNS cord-006870-f5w6fw6q 5455 9 with with IN cord-006870-f5w6fw6q 5455 10 2 2 CD cord-006870-f5w6fw6q 5455 11 weeks week NNS cord-006870-f5w6fw6q 5455 12 slurred slur VBD cord-006870-f5w6fw6q 5455 13 speech speech NN cord-006870-f5w6fw6q 5455 14 and and CC cord-006870-f5w6fw6q 5455 15 worsening worsen VBG cord-006870-f5w6fw6q 5455 16 headache headache NN cord-006870-f5w6fw6q 5455 17 . . . cord-006870-f5w6fw6q 5456 1 An an DT cord-006870-f5w6fw6q 5456 2 enhancing enhance VBG cord-006870-f5w6fw6q 5456 3 lesion lesion NN cord-006870-f5w6fw6q 5456 4 on on IN cord-006870-f5w6fw6q 5456 5 brain brain NN cord-006870-f5w6fw6q 5456 6 MRI MRI NNP cord-006870-f5w6fw6q 5456 7 in in IN cord-006870-f5w6fw6q 5456 8 left leave VBN cord-006870-f5w6fw6q 5456 9 temporal temporal JJ cord-006870-f5w6fw6q 5456 10 lobe lobe NN cord-006870-f5w6fw6q 5456 11 was be VBD cord-006870-f5w6fw6q 5456 12 concerning concern VBG cord-006870-f5w6fw6q 5456 13 for for IN cord-006870-f5w6fw6q 5456 14 vasculitis vasculitis NN cord-006870-f5w6fw6q 5456 15 . . . cord-006870-f5w6fw6q 5457 1 Patient Patient NNP cord-006870-f5w6fw6q 5457 2 was be VBD cord-006870-f5w6fw6q 5457 3 treated treat VBN cord-006870-f5w6fw6q 5457 4 with with IN cord-006870-f5w6fw6q 5457 5 glucocorticoids glucocorticoid NNS cord-006870-f5w6fw6q 5457 6 , , , cord-006870-f5w6fw6q 5457 7 with with IN cord-006870-f5w6fw6q 5457 8 a a DT cord-006870-f5w6fw6q 5457 9 negative negative JJ cord-006870-f5w6fw6q 5457 10 rheumatologic rheumatologic JJ cord-006870-f5w6fw6q 5457 11 workup workup NN cord-006870-f5w6fw6q 5457 12 and and CC cord-006870-f5w6fw6q 5457 13 discharged discharge VBN cord-006870-f5w6fw6q 5457 14 home home RB cord-006870-f5w6fw6q 5457 15 . . . cord-006870-f5w6fw6q 5458 1 Patient Patient NNP cord-006870-f5w6fw6q 5458 2 subsequently subsequently RB cord-006870-f5w6fw6q 5458 3 presented present VBD cord-006870-f5w6fw6q 5458 4 2 2 CD cord-006870-f5w6fw6q 5458 5 days day NNS cord-006870-f5w6fw6q 5458 6 later later RB cord-006870-f5w6fw6q 5458 7 with with IN cord-006870-f5w6fw6q 5458 8 worsening worsen VBG cord-006870-f5w6fw6q 5458 9 symptoms symptom NNS cord-006870-f5w6fw6q 5458 10 , , , cord-006870-f5w6fw6q 5458 11 with with IN cord-006870-f5w6fw6q 5458 12 CT CT NNP cord-006870-f5w6fw6q 5458 13 imaging imaging NN cord-006870-f5w6fw6q 5458 14 showing showing NN cord-006870-f5w6fw6q 5458 15 completed complete VBN cord-006870-f5w6fw6q 5458 16 infarcts infarct NNS cord-006870-f5w6fw6q 5458 17 . . . cord-006870-f5w6fw6q 5459 1 Blood blood NN cord-006870-f5w6fw6q 5459 2 cultures culture NNS cord-006870-f5w6fw6q 5459 3 were be VBD cord-006870-f5w6fw6q 5459 4 positive positive JJ cord-006870-f5w6fw6q 5459 5 for for IN cord-006870-f5w6fw6q 5459 6 Cryptococcus Cryptococcus NNP cord-006870-f5w6fw6q 5459 7 Neoformans Neoformans NNP cord-006870-f5w6fw6q 5459 8 ; ; : cord-006870-f5w6fw6q 5459 9 patient patient NN cord-006870-f5w6fw6q 5459 10 died die VBD cord-006870-f5w6fw6q 5459 11 due due JJ cord-006870-f5w6fw6q 5459 12 to to TO cord-006870-f5w6fw6q 5459 13 diffuse diffuse VB cord-006870-f5w6fw6q 5459 14 right right JJ cord-006870-f5w6fw6q 5459 15 MCA MCA NNP cord-006870-f5w6fw6q 5459 16 territory territory NN cord-006870-f5w6fw6q 5459 17 edema edema NN cord-006870-f5w6fw6q 5459 18 and and CC cord-006870-f5w6fw6q 5459 19 brain brain NN cord-006870-f5w6fw6q 5459 20 herniation herniation NN cord-006870-f5w6fw6q 5459 21 syndrome syndrome NN cord-006870-f5w6fw6q 5459 22 . . . cord-006870-f5w6fw6q 5460 1 Discussion discussion NN cord-006870-f5w6fw6q 5460 2 : : : cord-006870-f5w6fw6q 5461 1 It -PRON- PRP cord-006870-f5w6fw6q 5461 2 is be VBZ cord-006870-f5w6fw6q 5461 3 important important JJ cord-006870-f5w6fw6q 5461 4 to to TO cord-006870-f5w6fw6q 5461 5 consider consider VB cord-006870-f5w6fw6q 5461 6 CNS CNS NNP cord-006870-f5w6fw6q 5461 7 infection infection NN cord-006870-f5w6fw6q 5461 8 even even RB cord-006870-f5w6fw6q 5461 9 in in IN cord-006870-f5w6fw6q 5461 10 immunocompetent immunocompetent JJ cord-006870-f5w6fw6q 5461 11 patients patient NNS cord-006870-f5w6fw6q 5461 12 who who WP cord-006870-f5w6fw6q 5461 13 present present VBP cord-006870-f5w6fw6q 5461 14 with with IN cord-006870-f5w6fw6q 5461 15 any any DT cord-006870-f5w6fw6q 5461 16 of of IN cord-006870-f5w6fw6q 5461 17 the the DT cord-006870-f5w6fw6q 5461 18 following follow VBG cord-006870-f5w6fw6q 5461 19 : : : cord-006870-f5w6fw6q 5461 20 fever fever NN cord-006870-f5w6fw6q 5461 21 , , , cord-006870-f5w6fw6q 5461 22 nuchal nuchal NN cord-006870-f5w6fw6q 5461 23 rigidity rigidity NN cord-006870-f5w6fw6q 5461 24 , , , cord-006870-f5w6fw6q 5461 25 mental mental JJ cord-006870-f5w6fw6q 5461 26 status status NN cord-006870-f5w6fw6q 5461 27 change change NN cord-006870-f5w6fw6q 5461 28 , , , cord-006870-f5w6fw6q 5461 29 and and CC cord-006870-f5w6fw6q 5461 30 headache headache NN cord-006870-f5w6fw6q 5461 31 . . . cord-006870-f5w6fw6q 5462 1 CNS CNS NNP cord-006870-f5w6fw6q 5462 2 vasculitis vasculitis NN cord-006870-f5w6fw6q 5462 3 in in IN cord-006870-f5w6fw6q 5462 4 association association NN cord-006870-f5w6fw6q 5462 5 with with IN cord-006870-f5w6fw6q 5462 6 infection infection NN cord-006870-f5w6fw6q 5462 7 is be VBZ cord-006870-f5w6fw6q 5462 8 caused cause VBN cord-006870-f5w6fw6q 5462 9 by by IN cord-006870-f5w6fw6q 5462 10 basilar basilar JJ cord-006870-f5w6fw6q 5462 11 meningeal meningeal JJ cord-006870-f5w6fw6q 5462 12 exudates exudate NNS cord-006870-f5w6fw6q 5462 13 . . . cord-006870-f5w6fw6q 5463 1 These these DT cord-006870-f5w6fw6q 5463 2 cause cause VBP cord-006870-f5w6fw6q 5463 3 traversing traverse VBG cord-006870-f5w6fw6q 5463 4 vessels vessel NNS cord-006870-f5w6fw6q 5463 5 to to TO cord-006870-f5w6fw6q 5463 6 become become VB cord-006870-f5w6fw6q 5463 7 inflamed inflamed JJ cord-006870-f5w6fw6q 5463 8 , , , cord-006870-f5w6fw6q 5463 9 leading lead VBG cord-006870-f5w6fw6q 5463 10 to to IN cord-006870-f5w6fw6q 5463 11 distal distal JJ cord-006870-f5w6fw6q 5463 12 inflammation inflammation NN cord-006870-f5w6fw6q 5463 13 and and CC cord-006870-f5w6fw6q 5463 14 subsequent subsequent JJ cord-006870-f5w6fw6q 5463 15 thrombus thrombus NN cord-006870-f5w6fw6q 5463 16 and and CC cord-006870-f5w6fw6q 5463 17 infarction infarction NN cord-006870-f5w6fw6q 5463 18 . . . cord-006870-f5w6fw6q 5464 1 We -PRON- PRP cord-006870-f5w6fw6q 5464 2 present present VBP cord-006870-f5w6fw6q 5464 3 a a DT cord-006870-f5w6fw6q 5464 4 right right JJ cord-006870-f5w6fw6q 5464 5 MCA MCA NNP cord-006870-f5w6fw6q 5464 6 territory territory NN cord-006870-f5w6fw6q 5464 7 infarct infarct NNP cord-006870-f5w6fw6q 5464 8 , , , cord-006870-f5w6fw6q 5464 9 presumed presume VBN cord-006870-f5w6fw6q 5464 10 to to TO cord-006870-f5w6fw6q 5464 11 be be VB cord-006870-f5w6fw6q 5464 12 based base VBN cord-006870-f5w6fw6q 5464 13 on on IN cord-006870-f5w6fw6q 5464 14 the the DT cord-006870-f5w6fw6q 5464 15 aforementioned aforementioned JJ cord-006870-f5w6fw6q 5464 16 vasculitic vasculitic JJ cord-006870-f5w6fw6q 5464 17 process process NN cord-006870-f5w6fw6q 5464 18 . . . cord-006870-f5w6fw6q 5465 1 When when WRB cord-006870-f5w6fw6q 5465 2 acute acute JJ cord-006870-f5w6fw6q 5465 3 infarcts infarct NNS cord-006870-f5w6fw6q 5465 4 are be VBP cord-006870-f5w6fw6q 5465 5 associated associate VBN cord-006870-f5w6fw6q 5465 6 with with IN cord-006870-f5w6fw6q 5465 7 opportunistic opportunistic JJ cord-006870-f5w6fw6q 5465 8 CNS CNS NNP cord-006870-f5w6fw6q 5465 9 infections infection NNS cord-006870-f5w6fw6q 5465 10 , , , cord-006870-f5w6fw6q 5465 11 they -PRON- PRP cord-006870-f5w6fw6q 5465 12 are be VBP cord-006870-f5w6fw6q 5465 13 usually usually RB cord-006870-f5w6fw6q 5465 14 not not RB cord-006870-f5w6fw6q 5465 15 associated associate VBN cord-006870-f5w6fw6q 5465 16 with with IN cord-006870-f5w6fw6q 5465 17 large large JJ cord-006870-f5w6fw6q 5465 18 vessel vessel NN cord-006870-f5w6fw6q 5465 19 infarction infarction NN cord-006870-f5w6fw6q 5465 20 . . . cord-006870-f5w6fw6q 5466 1 We -PRON- PRP cord-006870-f5w6fw6q 5466 2 also also RB cord-006870-f5w6fw6q 5466 3 examine examine VBP cord-006870-f5w6fw6q 5466 4 the the DT cord-006870-f5w6fw6q 5466 5 adjunctive adjunctive JJ cord-006870-f5w6fw6q 5466 6 use use NN cord-006870-f5w6fw6q 5466 7 of of IN cord-006870-f5w6fw6q 5466 8 glucocorticoid glucocorticoid NN cord-006870-f5w6fw6q 5466 9 therapy therapy NN cord-006870-f5w6fw6q 5466 10 for for IN cord-006870-f5w6fw6q 5466 11 treatment treatment NN cord-006870-f5w6fw6q 5466 12 of of IN cord-006870-f5w6fw6q 5466 13 fungal fungal JJ cord-006870-f5w6fw6q 5466 14 CNS CNS NNP cord-006870-f5w6fw6q 5466 15 infections infection NNS cord-006870-f5w6fw6q 5466 16 . . . cord-006870-f5w6fw6q 5467 1 This this DT cord-006870-f5w6fw6q 5467 2 is be VBZ cord-006870-f5w6fw6q 5467 3 an an DT cord-006870-f5w6fw6q 5467 4 infrequent infrequent JJ cord-006870-f5w6fw6q 5467 5 case case NN cord-006870-f5w6fw6q 5467 6 of of IN cord-006870-f5w6fw6q 5467 7 Cryptococcus Cryptococcus NNP cord-006870-f5w6fw6q 5467 8 Neoformans Neoformans NNP cord-006870-f5w6fw6q 5467 9 causing cause VBG cord-006870-f5w6fw6q 5467 10 a a DT cord-006870-f5w6fw6q 5467 11 CNS CNS NNP cord-006870-f5w6fw6q 5467 12 infection infection NN cord-006870-f5w6fw6q 5467 13 in in IN cord-006870-f5w6fw6q 5467 14 an an DT cord-006870-f5w6fw6q 5467 15 HIV HIV NNP cord-006870-f5w6fw6q 5467 16 - - HYPH cord-006870-f5w6fw6q 5467 17 seronegative seronegative JJ cord-006870-f5w6fw6q 5467 18 patient patient NN cord-006870-f5w6fw6q 5467 19 not not RB cord-006870-f5w6fw6q 5467 20 on on IN cord-006870-f5w6fw6q 5467 21 chronic chronic JJ cord-006870-f5w6fw6q 5467 22 immunosuppressive immunosuppressive JJ cord-006870-f5w6fw6q 5467 23 medications medication NNS cord-006870-f5w6fw6q 5467 24 . . . cord-006870-f5w6fw6q 5468 1 This this DT cord-006870-f5w6fw6q 5468 2 case case NN cord-006870-f5w6fw6q 5468 3 presents present VBZ cord-006870-f5w6fw6q 5468 4 a a DT cord-006870-f5w6fw6q 5468 5 unique unique JJ cord-006870-f5w6fw6q 5468 6 complication complication NN cord-006870-f5w6fw6q 5468 7 of of IN cord-006870-f5w6fw6q 5468 8 Cryptococcal cryptococcal JJ cord-006870-f5w6fw6q 5468 9 infections infection NNS cord-006870-f5w6fw6q 5468 10 , , , cord-006870-f5w6fw6q 5468 11 a a DT cord-006870-f5w6fw6q 5468 12 CNS CNS NNP cord-006870-f5w6fw6q 5468 13 vasculitis vasculitis NN cord-006870-f5w6fw6q 5468 14 leading lead VBG cord-006870-f5w6fw6q 5468 15 to to IN cord-006870-f5w6fw6q 5468 16 infarction infarction NN cord-006870-f5w6fw6q 5468 17 in in IN cord-006870-f5w6fw6q 5468 18 a a DT cord-006870-f5w6fw6q 5468 19 large large JJ cord-006870-f5w6fw6q 5468 20 vessel vessel NN cord-006870-f5w6fw6q 5468 21 territory territory NN cord-006870-f5w6fw6q 5468 22 . . . cord-006870-f5w6fw6q 5469 1 We -PRON- PRP cord-006870-f5w6fw6q 5469 2 describe describe VBP cord-006870-f5w6fw6q 5469 3 the the DT cord-006870-f5w6fw6q 5469 4 baseline baseline JJ cord-006870-f5w6fw6q 5469 5 characteristics characteristic NNS cord-006870-f5w6fw6q 5469 6 , , , cord-006870-f5w6fw6q 5469 7 continuous continuous JJ cord-006870-f5w6fw6q 5469 8 intravenous intravenous JJ cord-006870-f5w6fw6q 5469 9 midazolam midazolam NN cord-006870-f5w6fw6q 5469 10 doses dose NNS cord-006870-f5w6fw6q 5469 11 , , , cord-006870-f5w6fw6q 5469 12 seizure seizure NN cord-006870-f5w6fw6q 5469 13 control control NN cord-006870-f5w6fw6q 5469 14 , , , cord-006870-f5w6fw6q 5469 15 hospital hospital NN cord-006870-f5w6fw6q 5469 16 course course NN cord-006870-f5w6fw6q 5469 17 and and CC cord-006870-f5w6fw6q 5469 18 outcomes outcome NNS cord-006870-f5w6fw6q 5469 19 in in IN cord-006870-f5w6fw6q 5469 20 patients patient NNS cord-006870-f5w6fw6q 5469 21 who who WP cord-006870-f5w6fw6q 5469 22 received receive VBD cord-006870-f5w6fw6q 5469 23 high high JJ cord-006870-f5w6fw6q 5469 24 dose dose NN cord-006870-f5w6fw6q 5469 25 continuous continuous JJ cord-006870-f5w6fw6q 5469 26 midazolam midazolam NN cord-006870-f5w6fw6q 5469 27 infusion infusion NN cord-006870-f5w6fw6q 5469 28 for for IN cord-006870-f5w6fw6q 5469 29 refractory refractory JJ cord-006870-f5w6fw6q 5469 30 status status NN cord-006870-f5w6fw6q 5469 31 epilepticus epilepticus NN cord-006870-f5w6fw6q 5470 1 In in IN cord-006870-f5w6fw6q 5470 2 this this DT cord-006870-f5w6fw6q 5470 3 retrospective retrospective JJ cord-006870-f5w6fw6q 5470 4 case case NN cord-006870-f5w6fw6q 5470 5 series series NN cord-006870-f5w6fw6q 5470 6 study study NN cord-006870-f5w6fw6q 5470 7 , , , cord-006870-f5w6fw6q 5470 8 we -PRON- PRP cord-006870-f5w6fw6q 5470 9 evaluated evaluate VBD cord-006870-f5w6fw6q 5470 10 adult adult NN cord-006870-f5w6fw6q 5470 11 patients patient NNS cord-006870-f5w6fw6q 5470 12 with with IN cord-006870-f5w6fw6q 5470 13 refractory refractory JJ cord-006870-f5w6fw6q 5470 14 status status NN cord-006870-f5w6fw6q 5470 15 epilepticus epilepticus NN cord-006870-f5w6fw6q 5470 16 treated treat VBN cord-006870-f5w6fw6q 5470 17 with with IN cord-006870-f5w6fw6q 5470 18 high high JJ cord-006870-f5w6fw6q 5470 19 continuous continuous JJ cord-006870-f5w6fw6q 5470 20 intravenous intravenous NN cord-006870-f5w6fw6q 5470 21 midazolam midazolam NN cord-006870-f5w6fw6q 5470 22 doses dose NNS cord-006870-f5w6fw6q 5470 23 in in IN cord-006870-f5w6fw6q 5470 24 an an DT cord-006870-f5w6fw6q 5470 25 academic academic JJ cord-006870-f5w6fw6q 5470 26 neurocritical neurocritical NNP cord-006870-f5w6fw6q 5470 27 care care NN cord-006870-f5w6fw6q 5470 28 unit unit NN cord-006870-f5w6fw6q 5470 29 between between IN cord-006870-f5w6fw6q 5470 30 August August NNP cord-006870-f5w6fw6q 5470 31 2016 2016 CD cord-006870-f5w6fw6q 5470 32 and and CC cord-006870-f5w6fw6q 5470 33 June June NNP cord-006870-f5w6fw6q 5470 34 2017 2017 CD cord-006870-f5w6fw6q 5470 35 . . . cord-006870-f5w6fw6q 5471 1 Four four CD cord-006870-f5w6fw6q 5471 2 patients patient NNS cord-006870-f5w6fw6q 5471 3 were be VBD cord-006870-f5w6fw6q 5471 4 identified identify VBN cord-006870-f5w6fw6q 5471 5 . . . cord-006870-f5w6fw6q 5472 1 The the DT cord-006870-f5w6fw6q 5472 2 maximum maximum JJ cord-006870-f5w6fw6q 5472 3 midazolam midazolam NN cord-006870-f5w6fw6q 5472 4 dose dose NN cord-006870-f5w6fw6q 5472 5 for for IN cord-006870-f5w6fw6q 5472 6 each each DT cord-006870-f5w6fw6q 5472 7 patient patient NN cord-006870-f5w6fw6q 5472 8 was be VBD cord-006870-f5w6fw6q 5472 9 : : : cord-006870-f5w6fw6q 5472 10 Withdrawal withdrawal NN cord-006870-f5w6fw6q 5472 11 seizures seizure NNS cord-006870-f5w6fw6q 5472 12 ( ( -LRB- cord-006870-f5w6fw6q 5472 13 occurring occur VBG cord-006870-f5w6fw6q 5472 14 within within IN cord-006870-f5w6fw6q 5472 15 48 48 CD cord-006870-f5w6fw6q 5472 16 hours hour NNS cord-006870-f5w6fw6q 5472 17 of of IN cord-006870-f5w6fw6q 5472 18 discontinuation discontinuation NN cord-006870-f5w6fw6q 5472 19 of of IN cord-006870-f5w6fw6q 5472 20 continuous continuous JJ cord-006870-f5w6fw6q 5472 21 iv iv NNP cord-006870-f5w6fw6q 5472 22 midazolam midazolam NNP cord-006870-f5w6fw6q 5472 23 ) ) -RRB- cord-006870-f5w6fw6q 5472 24 occurred occur VBD cord-006870-f5w6fw6q 5472 25 in in IN cord-006870-f5w6fw6q 5472 26 Patient Patient NNP cord-006870-f5w6fw6q 5472 27 B. B. NNP cord-006870-f5w6fw6q 5472 28 " " '' cord-006870-f5w6fw6q 5472 29 Ultimate ultimate JJ cord-006870-f5w6fw6q 5472 30 continuous continuous JJ cord-006870-f5w6fw6q 5472 31 iv iv FW cord-006870-f5w6fw6q 5472 32 midazolam midazolam NNP cord-006870-f5w6fw6q 5472 33 failure failure NN cord-006870-f5w6fw6q 5472 34 " " '' cord-006870-f5w6fw6q 5472 35 ( ( -LRB- cord-006870-f5w6fw6q 5472 36 patient patient JJ cord-006870-f5w6fw6q 5472 37 requiring require VBG cord-006870-f5w6fw6q 5472 38 change change NN cord-006870-f5w6fw6q 5472 39 to to IN cord-006870-f5w6fw6q 5472 40 a a DT cord-006870-f5w6fw6q 5472 41 different different JJ cord-006870-f5w6fw6q 5472 42 continuous continuous JJ cord-006870-f5w6fw6q 5472 43 intravenous intravenous JJ cord-006870-f5w6fw6q 5472 44 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 5472 45 drug drug NN cord-006870-f5w6fw6q 5472 46 despite despite IN cord-006870-f5w6fw6q 5472 47 maximum maximum JJ cord-006870-f5w6fw6q 5472 48 optimized optimize VBN cord-006870-f5w6fw6q 5472 49 dose dose NN cord-006870-f5w6fw6q 5472 50 ) ) -RRB- cord-006870-f5w6fw6q 5472 51 was be VBD cord-006870-f5w6fw6q 5472 52 not not RB cord-006870-f5w6fw6q 5472 53 observed observe VBN cord-006870-f5w6fw6q 5472 54 in in IN cord-006870-f5w6fw6q 5472 55 any any DT cord-006870-f5w6fw6q 5472 56 of of IN cord-006870-f5w6fw6q 5472 57 the the DT cord-006870-f5w6fw6q 5472 58 four four CD cord-006870-f5w6fw6q 5472 59 patients patient NNS cord-006870-f5w6fw6q 5472 60 . . . cord-006870-f5w6fw6q 5473 1 Hospital hospital NN cord-006870-f5w6fw6q 5473 2 complications complication NNS cord-006870-f5w6fw6q 5473 3 occurred occur VBD cord-006870-f5w6fw6q 5473 4 in in IN cord-006870-f5w6fw6q 5473 5 patient patient JJ cord-006870-f5w6fw6q 5473 6 A a NN cord-006870-f5w6fw6q 5473 7 and and CC cord-006870-f5w6fw6q 5473 8 B b NN cord-006870-f5w6fw6q 5473 9 due due IN cord-006870-f5w6fw6q 5473 10 to to IN cord-006870-f5w6fw6q 5473 11 infections infection NNS cord-006870-f5w6fw6q 5473 12 . . . cord-006870-f5w6fw6q 5474 1 Hypotension hypotension NN cord-006870-f5w6fw6q 5474 2 related relate VBN cord-006870-f5w6fw6q 5474 3 to to IN cord-006870-f5w6fw6q 5474 4 continuous continuous JJ cord-006870-f5w6fw6q 5474 5 infusion infusion NN cord-006870-f5w6fw6q 5474 6 midazolam midazolam NN cord-006870-f5w6fw6q 5474 7 occurred occur VBD cord-006870-f5w6fw6q 5474 8 in in IN cord-006870-f5w6fw6q 5474 9 patient patient NN cord-006870-f5w6fw6q 5474 10 A. a. NN cord-006870-f5w6fw6q 5474 11 Three Three NNP cord-006870-f5w6fw6q 5474 12 out out IN cord-006870-f5w6fw6q 5474 13 of of IN cord-006870-f5w6fw6q 5474 14 four four CD cord-006870-f5w6fw6q 5474 15 patients patient NNS cord-006870-f5w6fw6q 5474 16 discharged discharge VBN cord-006870-f5w6fw6q 5474 17 alive alive JJ cord-006870-f5w6fw6q 5474 18 to to IN cord-006870-f5w6fw6q 5474 19 a a DT cord-006870-f5w6fw6q 5474 20 skilled skilled JJ cord-006870-f5w6fw6q 5474 21 nursing nursing NN cord-006870-f5w6fw6q 5474 22 facility facility NN cord-006870-f5w6fw6q 5474 23 ; ; : cord-006870-f5w6fw6q 5474 24 after after IN cord-006870-f5w6fw6q 5474 25 a a DT cord-006870-f5w6fw6q 5474 26 goals goal NNS cord-006870-f5w6fw6q 5474 27 of of IN cord-006870-f5w6fw6q 5474 28 care care NN cord-006870-f5w6fw6q 5474 29 discussion discussion NN cord-006870-f5w6fw6q 5474 30 with with IN cord-006870-f5w6fw6q 5474 31 the the DT cord-006870-f5w6fw6q 5474 32 family family NN cord-006870-f5w6fw6q 5474 33 , , , cord-006870-f5w6fw6q 5474 34 the the DT cord-006870-f5w6fw6q 5474 35 fourth fourth JJ cord-006870-f5w6fw6q 5474 36 patient patient NN cord-006870-f5w6fw6q 5474 37 had have VBD cord-006870-f5w6fw6q 5474 38 withdrawal withdrawal NN cord-006870-f5w6fw6q 5474 39 of of IN cord-006870-f5w6fw6q 5474 40 care care NN cord-006870-f5w6fw6q 5474 41 due due IN cord-006870-f5w6fw6q 5474 42 to to IN cord-006870-f5w6fw6q 5474 43 the the DT cord-006870-f5w6fw6q 5474 44 severity severity NN cord-006870-f5w6fw6q 5474 45 of of IN cord-006870-f5w6fw6q 5474 46 his -PRON- PRP$ cord-006870-f5w6fw6q 5474 47 brain brain NN cord-006870-f5w6fw6q 5474 48 injury injury NN cord-006870-f5w6fw6q 5474 49 . . . cord-006870-f5w6fw6q 5475 1 In in IN cord-006870-f5w6fw6q 5475 2 this this DT cord-006870-f5w6fw6q 5475 3 case case NN cord-006870-f5w6fw6q 5475 4 series series NN cord-006870-f5w6fw6q 5475 5 , , , cord-006870-f5w6fw6q 5475 6 we -PRON- PRP cord-006870-f5w6fw6q 5475 7 report report VBP cord-006870-f5w6fw6q 5475 8 the the DT cord-006870-f5w6fw6q 5475 9 use use NN cord-006870-f5w6fw6q 5475 10 of of IN cord-006870-f5w6fw6q 5475 11 high high JJ cord-006870-f5w6fw6q 5475 12 dose dose NN cord-006870-f5w6fw6q 5475 13 continuous continuous JJ cord-006870-f5w6fw6q 5475 14 IV IV NNP cord-006870-f5w6fw6q 5475 15 midazolam midazolam NN cord-006870-f5w6fw6q 5475 16 for for IN cord-006870-f5w6fw6q 5475 17 treatment treatment NN cord-006870-f5w6fw6q 5475 18 of of IN cord-006870-f5w6fw6q 5475 19 refractory refractory JJ cord-006870-f5w6fw6q 5475 20 status status NN cord-006870-f5w6fw6q 5475 21 epilepticus epilepticus NN cord-006870-f5w6fw6q 5475 22 . . . cord-006870-f5w6fw6q 5476 1 There there EX cord-006870-f5w6fw6q 5476 2 were be VBD cord-006870-f5w6fw6q 5476 3 no no DT cord-006870-f5w6fw6q 5476 4 midazolam midazolam NN cord-006870-f5w6fw6q 5476 5 - - HYPH cord-006870-f5w6fw6q 5476 6 related relate VBN cord-006870-f5w6fw6q 5476 7 deaths death NNS cord-006870-f5w6fw6q 5476 8 . . . cord-006870-f5w6fw6q 5477 1 Neurologic neurologic JJ cord-006870-f5w6fw6q 5477 2 complications complication NNS cord-006870-f5w6fw6q 5477 3 in in IN cord-006870-f5w6fw6q 5477 4 Infective Infective NNP cord-006870-f5w6fw6q 5477 5 Endocarditis Endocarditis NNP cord-006870-f5w6fw6q 5477 6 ( ( -LRB- cord-006870-f5w6fw6q 5477 7 IE IE NNP cord-006870-f5w6fw6q 5477 8 ) ) -RRB- cord-006870-f5w6fw6q 5477 9 occur occur VBP cord-006870-f5w6fw6q 5477 10 up up IN cord-006870-f5w6fw6q 5477 11 to to TO cord-006870-f5w6fw6q 5477 12 35 35 CD cord-006870-f5w6fw6q 5477 13 % % NN cord-006870-f5w6fw6q 5477 14 and and CC cord-006870-f5w6fw6q 5477 15 are be VBP cord-006870-f5w6fw6q 5477 16 independent independent JJ cord-006870-f5w6fw6q 5477 17 predictors predictor NNS cord-006870-f5w6fw6q 5477 18 of of IN cord-006870-f5w6fw6q 5477 19 mortality mortality NN cord-006870-f5w6fw6q 5477 20 . . . cord-006870-f5w6fw6q 5478 1 Infectious infectious JJ cord-006870-f5w6fw6q 5478 2 intracranial intracranial JJ cord-006870-f5w6fw6q 5478 3 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5478 4 known know VBN cord-006870-f5w6fw6q 5478 5 as as IN cord-006870-f5w6fw6q 5478 6 " " `` cord-006870-f5w6fw6q 5478 7 mycotic mycotic JJ cord-006870-f5w6fw6q 5478 8 aneurysm aneurysm NN cord-006870-f5w6fw6q 5478 9 " " '' cord-006870-f5w6fw6q 5478 10 ( ( -LRB- cord-006870-f5w6fw6q 5478 11 MA MA NNP cord-006870-f5w6fw6q 5478 12 ) ) -RRB- cord-006870-f5w6fw6q 5478 13 are be VBP cord-006870-f5w6fw6q 5478 14 rare rare JJ cord-006870-f5w6fw6q 5478 15 constituting constitute VBG cord-006870-f5w6fw6q 5478 16 2 2 CD cord-006870-f5w6fw6q 5478 17 - - SYM cord-006870-f5w6fw6q 5478 18 5 5 CD cord-006870-f5w6fw6q 5478 19 % % NN cord-006870-f5w6fw6q 5478 20 . . . cord-006870-f5w6fw6q 5479 1 Hemorrhaging hemorrhage VBG cord-006870-f5w6fw6q 5479 2 rate rate NN cord-006870-f5w6fw6q 5479 3 is be VBZ cord-006870-f5w6fw6q 5479 4 50 50 CD cord-006870-f5w6fw6q 5479 5 % % NN cord-006870-f5w6fw6q 5479 6 . . . cord-006870-f5w6fw6q 5480 1 Mortality mortality NN cord-006870-f5w6fw6q 5480 2 is be VBZ cord-006870-f5w6fw6q 5480 3 80 80 CD cord-006870-f5w6fw6q 5480 4 % % NN cord-006870-f5w6fw6q 5480 5 with with IN cord-006870-f5w6fw6q 5480 6 rupture rupture NN cord-006870-f5w6fw6q 5480 7 . . . cord-006870-f5w6fw6q 5481 1 Ruptured ruptured JJ cord-006870-f5w6fw6q 5481 2 MA MA NNP cord-006870-f5w6fw6q 5481 3 poses pose VBZ cord-006870-f5w6fw6q 5481 4 significant significant JJ cord-006870-f5w6fw6q 5481 5 management management NN cord-006870-f5w6fw6q 5481 6 conundrum conundrum NN cord-006870-f5w6fw6q 5481 7 due due IN cord-006870-f5w6fw6q 5481 8 to to IN cord-006870-f5w6fw6q 5481 9 lack lack NN cord-006870-f5w6fw6q 5481 10 of of IN cord-006870-f5w6fw6q 5481 11 available available JJ cord-006870-f5w6fw6q 5481 12 solid solid JJ cord-006870-f5w6fw6q 5481 13 prospective prospective JJ cord-006870-f5w6fw6q 5481 14 data datum NNS cord-006870-f5w6fw6q 5481 15 guiding guide VBG cord-006870-f5w6fw6q 5481 16 the the DT cord-006870-f5w6fw6q 5481 17 order order NN cord-006870-f5w6fw6q 5481 18 ( ( -LRB- cord-006870-f5w6fw6q 5481 19 cardiac cardiac NN cord-006870-f5w6fw6q 5481 20 vs vs IN cord-006870-f5w6fw6q 5481 21 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 5481 22 ) ) -RRB- cord-006870-f5w6fw6q 5481 23 or or CC cord-006870-f5w6fw6q 5481 24 timing timing NN cord-006870-f5w6fw6q 5481 25 ( ( -LRB- cord-006870-f5w6fw6q 5481 26 early early RB cord-006870-f5w6fw6q 5481 27 vs vs IN cord-006870-f5w6fw6q 5481 28 delayed delay VBN cord-006870-f5w6fw6q 5481 29 ) ) -RRB- cord-006870-f5w6fw6q 5481 30 of of IN cord-006870-f5w6fw6q 5481 31 surgery surgery NN cord-006870-f5w6fw6q 5481 32 . . . cord-006870-f5w6fw6q 5482 1 A a DT cord-006870-f5w6fw6q 5482 2 34y 34y NNS cord-006870-f5w6fw6q 5482 3 / / SYM cord-006870-f5w6fw6q 5482 4 o o NN cord-006870-f5w6fw6q 5482 5 male male JJ cord-006870-f5w6fw6q 5482 6 IV IV NNP cord-006870-f5w6fw6q 5482 7 drug drug NN cord-006870-f5w6fw6q 5482 8 abuser abuser NN cord-006870-f5w6fw6q 5482 9 presented present VBN cord-006870-f5w6fw6q 5482 10 with with IN cord-006870-f5w6fw6q 5482 11 acute acute JJ cord-006870-f5w6fw6q 5482 12 hypoxemic hypoxemic JJ cord-006870-f5w6fw6q 5482 13 respiratory respiratory JJ cord-006870-f5w6fw6q 5482 14 failure failure NN cord-006870-f5w6fw6q 5482 15 secondary secondary JJ cord-006870-f5w6fw6q 5482 16 to to IN cord-006870-f5w6fw6q 5482 17 pneumonia pneumonia NN cord-006870-f5w6fw6q 5482 18 and and CC cord-006870-f5w6fw6q 5482 19 suspected suspect VBN cord-006870-f5w6fw6q 5482 20 meningitis meningitis NN cord-006870-f5w6fw6q 5482 21 . . . cord-006870-f5w6fw6q 5483 1 GSC GSC NNP cord-006870-f5w6fw6q 5483 2 6 6 CD cord-006870-f5w6fw6q 5483 3 intubated intubate VBD cord-006870-f5w6fw6q 5483 4 on on IN cord-006870-f5w6fw6q 5483 5 IV IV NNP cord-006870-f5w6fw6q 5483 6 antibiotic antibiotic NN cord-006870-f5w6fw6q 5483 7 . . . cord-006870-f5w6fw6q 5484 1 Hemodynamic Hemodynamic NNP cord-006870-f5w6fw6q 5484 2 instability instability NN cord-006870-f5w6fw6q 5484 3 prompted prompt VBD cord-006870-f5w6fw6q 5484 4 TEE tee NN cord-006870-f5w6fw6q 5484 5 showing show VBG cord-006870-f5w6fw6q 5484 6 Large large JJ cord-006870-f5w6fw6q 5484 7 aortic aortic JJ cord-006870-f5w6fw6q 5484 8 valve valve NN cord-006870-f5w6fw6q 5484 9 vegetation vegetation NN cord-006870-f5w6fw6q 5484 10 . . . cord-006870-f5w6fw6q 5485 1 Blood blood NN cord-006870-f5w6fw6q 5485 2 cultures culture NNS cord-006870-f5w6fw6q 5486 1 positive positive JJ cord-006870-f5w6fw6q 5486 2 MSSA MSSA NNP cord-006870-f5w6fw6q 5486 3 fulfilled fulfil VBD cord-006870-f5w6fw6q 5486 4 criteria criterion NNS cord-006870-f5w6fw6q 5486 5 for for IN cord-006870-f5w6fw6q 5486 6 IE IE NNP cord-006870-f5w6fw6q 5486 7 . . . cord-006870-f5w6fw6q 5487 1 Tests test NNS cord-006870-f5w6fw6q 5487 2 showed show VBD cord-006870-f5w6fw6q 5487 3 kidneys kidney NNS cord-006870-f5w6fw6q 5487 4 infarctions infarction NNS cord-006870-f5w6fw6q 5487 5 . . . cord-006870-f5w6fw6q 5488 1 CT CT NNP cord-006870-f5w6fw6q 5488 2 brain brain NN cord-006870-f5w6fw6q 5488 3 showed show VBD cord-006870-f5w6fw6q 5488 4 R R NNP cord-006870-f5w6fw6q 5488 5 MCA MCA NNP cord-006870-f5w6fw6q 5488 6 territory territory NN cord-006870-f5w6fw6q 5488 7 infarct infarct NN cord-006870-f5w6fw6q 5488 8 with with IN cord-006870-f5w6fw6q 5488 9 SAH.CTA SAH.CTA NNP cord-006870-f5w6fw6q 5488 10 head head NN cord-006870-f5w6fw6q 5488 11 revealed reveal VBD cord-006870-f5w6fw6q 5488 12 small small JJ cord-006870-f5w6fw6q 5488 13 MA MA NNP cord-006870-f5w6fw6q 5488 14 along along IN cord-006870-f5w6fw6q 5488 15 the the DT cord-006870-f5w6fw6q 5488 16 distal distal JJ cord-006870-f5w6fw6q 5488 17 R R NNP cord-006870-f5w6fw6q 5488 18 MCA MCA NNP cord-006870-f5w6fw6q 5488 19 M4 M4 NNP cord-006870-f5w6fw6q 5488 20 branch branch NN cord-006870-f5w6fw6q 5488 21 confirmed confirm VBD cord-006870-f5w6fw6q 5488 22 with with IN cord-006870-f5w6fw6q 5488 23 cerebral cerebral JJ cord-006870-f5w6fw6q 5488 24 angiogram angiogram NN cord-006870-f5w6fw6q 5488 25 . . . cord-006870-f5w6fw6q 5489 1 Acute acute JJ cord-006870-f5w6fw6q 5489 2 heart heart NN cord-006870-f5w6fw6q 5489 3 failure failure NN cord-006870-f5w6fw6q 5489 4 and and CC cord-006870-f5w6fw6q 5489 5 arrhythmia arrhythmia NN cord-006870-f5w6fw6q 5489 6 led lead VBD cord-006870-f5w6fw6q 5489 7 discussion discussion NN cord-006870-f5w6fw6q 5489 8 on on IN cord-006870-f5w6fw6q 5489 9 cardiothoracic cardiothoracic JJ cord-006870-f5w6fw6q 5489 10 surgery surgery NN cord-006870-f5w6fw6q 5489 11 for for IN cord-006870-f5w6fw6q 5489 12 valve valve NN cord-006870-f5w6fw6q 5489 13 replacement replacement NN cord-006870-f5w6fw6q 5489 14 . . . cord-006870-f5w6fw6q 5490 1 Due due IN cord-006870-f5w6fw6q 5490 2 to to IN cord-006870-f5w6fw6q 5490 3 ruptured ruptured JJ cord-006870-f5w6fw6q 5490 4 MA MA NNP cord-006870-f5w6fw6q 5490 5 , , , cord-006870-f5w6fw6q 5490 6 decision decision NN cord-006870-f5w6fw6q 5490 7 to to TO cord-006870-f5w6fw6q 5490 8 secure secure VB cord-006870-f5w6fw6q 5490 9 it -PRON- PRP cord-006870-f5w6fw6q 5490 10 was be VBD cord-006870-f5w6fw6q 5490 11 made make VBN cord-006870-f5w6fw6q 5490 12 prior prior RB cord-006870-f5w6fw6q 5490 13 to to IN cord-006870-f5w6fw6q 5490 14 cardiac cardiac JJ cord-006870-f5w6fw6q 5490 15 surgery surgery NN cord-006870-f5w6fw6q 5490 16 . . . cord-006870-f5w6fw6q 5491 1 After after IN cord-006870-f5w6fw6q 5491 2 failed fail VBN cord-006870-f5w6fw6q 5491 3 endovascular endovascular JJ cord-006870-f5w6fw6q 5491 4 intervention intervention NN cord-006870-f5w6fw6q 5491 5 , , , cord-006870-f5w6fw6q 5491 6 patient patient JJ cord-006870-f5w6fw6q 5491 7 underwent undergo VBD cord-006870-f5w6fw6q 5491 8 surgical surgical JJ cord-006870-f5w6fw6q 5491 9 clipping clipping NN cord-006870-f5w6fw6q 5491 10 . . . cord-006870-f5w6fw6q 5492 1 Post post JJ cord-006870-f5w6fw6q 5492 2 operative operative NN cord-006870-f5w6fw6q 5492 3 MRI MRI NNP cord-006870-f5w6fw6q 5492 4 brain brain NN cord-006870-f5w6fw6q 5492 5 showed show VBD cord-006870-f5w6fw6q 5492 6 new new JJ cord-006870-f5w6fw6q 5492 7 infarcts infarct NNS cord-006870-f5w6fw6q 5492 8 suggesting suggest VBG cord-006870-f5w6fw6q 5492 9 recurrent recurrent JJ cord-006870-f5w6fw6q 5492 10 embolization embolization NN cord-006870-f5w6fw6q 5492 11 . . . cord-006870-f5w6fw6q 5493 1 Due due IN cord-006870-f5w6fw6q 5493 2 to to IN cord-006870-f5w6fw6q 5493 3 risk risk NN cord-006870-f5w6fw6q 5493 4 of of IN cord-006870-f5w6fw6q 5493 5 Intracranial intracranial JJ cord-006870-f5w6fw6q 5493 6 bleeding bleeding NN cord-006870-f5w6fw6q 5493 7 , , , cord-006870-f5w6fw6q 5493 8 cardiac cardiac JJ cord-006870-f5w6fw6q 5493 9 surgery surgery NN cord-006870-f5w6fw6q 5493 10 was be VBD cord-006870-f5w6fw6q 5493 11 postponed postpone VBN cord-006870-f5w6fw6q 5493 12 for for IN cord-006870-f5w6fw6q 5493 13 at at RB cord-006870-f5w6fw6q 5493 14 least least JJS cord-006870-f5w6fw6q 5493 15 2 2 CD cord-006870-f5w6fw6q 5493 16 weeks week NNS cord-006870-f5w6fw6q 5493 17 initially initially RB cord-006870-f5w6fw6q 5493 18 then then RB cord-006870-f5w6fw6q 5493 19 to to IN cord-006870-f5w6fw6q 5493 20 6 6 CD cord-006870-f5w6fw6q 5493 21 weeks week NNS cord-006870-f5w6fw6q 5493 22 . . . cord-006870-f5w6fw6q 5494 1 Patient Patient NNP cord-006870-f5w6fw6q 5494 2 underwent undergo VBD cord-006870-f5w6fw6q 5494 3 AVR AVR NNP cord-006870-f5w6fw6q 5494 4 after after IN cord-006870-f5w6fw6q 5494 5 completed complete VBN cord-006870-f5w6fw6q 5494 6 6 6 CD cord-006870-f5w6fw6q 5494 7 weeks week NNS cord-006870-f5w6fw6q 5494 8 of of IN cord-006870-f5w6fw6q 5494 9 antimicrobial antimicrobial JJ cord-006870-f5w6fw6q 5494 10 therapy therapy NN cord-006870-f5w6fw6q 5494 11 with with IN cord-006870-f5w6fw6q 5494 12 St St NNP cord-006870-f5w6fw6q 5494 13 Jude Jude NNP cord-006870-f5w6fw6q 5494 14 Mechanical Mechanical NNP cord-006870-f5w6fw6q 5494 15 Valve Valve NNP cord-006870-f5w6fw6q 5494 16 and and CC cord-006870-f5w6fw6q 5494 17 discharged discharge VBD cord-006870-f5w6fw6q 5494 18 on on IN cord-006870-f5w6fw6q 5494 19 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5494 20 with with IN cord-006870-f5w6fw6q 5494 21 a a DT cord-006870-f5w6fw6q 5494 22 Modified Modified NNP cord-006870-f5w6fw6q 5494 23 Rankin Rankin NNP cord-006870-f5w6fw6q 5494 24 scale scale NN cord-006870-f5w6fw6q 5494 25 of of IN cord-006870-f5w6fw6q 5494 26 1 1 CD cord-006870-f5w6fw6q 5494 27 . . . cord-006870-f5w6fw6q 5495 1 This this DT cord-006870-f5w6fw6q 5495 2 case case NN cord-006870-f5w6fw6q 5495 3 reflects reflect VBZ cord-006870-f5w6fw6q 5495 4 on on IN cord-006870-f5w6fw6q 5495 5 how how WRB cord-006870-f5w6fw6q 5495 6 urgent urgent JJ cord-006870-f5w6fw6q 5495 7 surgical surgical JJ cord-006870-f5w6fw6q 5495 8 intervention intervention NN cord-006870-f5w6fw6q 5495 9 should should MD cord-006870-f5w6fw6q 5495 10 take take VB cord-006870-f5w6fw6q 5495 11 place place NN cord-006870-f5w6fw6q 5495 12 . . . cord-006870-f5w6fw6q 5496 1 Safety safety NN cord-006870-f5w6fw6q 5496 2 period period NN cord-006870-f5w6fw6q 5496 3 between between IN cord-006870-f5w6fw6q 5496 4 neurological neurological JJ cord-006870-f5w6fw6q 5496 5 event event NN cord-006870-f5w6fw6q 5496 6 and and CC cord-006870-f5w6fw6q 5496 7 cardiac cardiac JJ cord-006870-f5w6fw6q 5496 8 surgery surgery NN cord-006870-f5w6fw6q 5496 9 is be VBZ cord-006870-f5w6fw6q 5496 10 largely largely RB cord-006870-f5w6fw6q 5496 11 debated debate VBN cord-006870-f5w6fw6q 5496 12 because because IN cord-006870-f5w6fw6q 5496 13 of of IN cord-006870-f5w6fw6q 5496 14 lack lack NN cord-006870-f5w6fw6q 5496 15 of of IN cord-006870-f5w6fw6q 5496 16 Controlled control VBN cord-006870-f5w6fw6q 5496 17 studies study NNS cord-006870-f5w6fw6q 5496 18 . . . cord-006870-f5w6fw6q 5497 1 There there EX cord-006870-f5w6fw6q 5497 2 has have VBZ cord-006870-f5w6fw6q 5497 3 been be VBN cord-006870-f5w6fw6q 5497 4 no no DT cord-006870-f5w6fw6q 5497 5 consensus consensus NN cord-006870-f5w6fw6q 5497 6 on on IN cord-006870-f5w6fw6q 5497 7 how how WRB cord-006870-f5w6fw6q 5497 8 to to TO cord-006870-f5w6fw6q 5497 9 approach approach VB cord-006870-f5w6fw6q 5497 10 those those DT cord-006870-f5w6fw6q 5497 11 cases case NNS cord-006870-f5w6fw6q 5497 12 as as IN cord-006870-f5w6fw6q 5497 13 paucity paucity NN cord-006870-f5w6fw6q 5497 14 of of IN cord-006870-f5w6fw6q 5497 15 robust robust JJ cord-006870-f5w6fw6q 5497 16 evidence evidence NN cord-006870-f5w6fw6q 5497 17 . . . cord-006870-f5w6fw6q 5498 1 Given give VBN cord-006870-f5w6fw6q 5498 2 their -PRON- PRP$ cord-006870-f5w6fw6q 5498 3 rarity rarity NN cord-006870-f5w6fw6q 5498 4 the the DT cord-006870-f5w6fw6q 5498 5 best good JJS cord-006870-f5w6fw6q 5498 6 management management NN cord-006870-f5w6fw6q 5498 7 modality modality NN cord-006870-f5w6fw6q 5498 8 remains remain VBZ cord-006870-f5w6fw6q 5498 9 unclear unclear JJ cord-006870-f5w6fw6q 5498 10 . . . cord-006870-f5w6fw6q 5499 1 This this DT cord-006870-f5w6fw6q 5499 2 case case NN cord-006870-f5w6fw6q 5499 3 stress stress VBP cord-006870-f5w6fw6q 5499 4 the the DT cord-006870-f5w6fw6q 5499 5 importance importance NN cord-006870-f5w6fw6q 5499 6 of of IN cord-006870-f5w6fw6q 5499 7 multimodal multimodal NN cord-006870-f5w6fw6q 5499 8 therapy therapy NN cord-006870-f5w6fw6q 5499 9 in in IN cord-006870-f5w6fw6q 5499 10 achieving achieve VBG cord-006870-f5w6fw6q 5499 11 good good JJ cord-006870-f5w6fw6q 5499 12 outcome outcome NN cord-006870-f5w6fw6q 5499 13 although although IN cord-006870-f5w6fw6q 5499 14 the the DT cord-006870-f5w6fw6q 5499 15 timing timing NN cord-006870-f5w6fw6q 5499 16 of of IN cord-006870-f5w6fw6q 5499 17 surgery surgery NN cord-006870-f5w6fw6q 5499 18 remains remain VBZ cord-006870-f5w6fw6q 5499 19 a a DT cord-006870-f5w6fw6q 5499 20 matter matter NN cord-006870-f5w6fw6q 5499 21 of of IN cord-006870-f5w6fw6q 5499 22 debate debate NN cord-006870-f5w6fw6q 5499 23 . . . cord-006870-f5w6fw6q 5500 1 We -PRON- PRP cord-006870-f5w6fw6q 5500 2 present present VBP cord-006870-f5w6fw6q 5500 3 a a DT cord-006870-f5w6fw6q 5500 4 patient patient NN cord-006870-f5w6fw6q 5500 5 with with IN cord-006870-f5w6fw6q 5500 6 vertebral vertebral JJ cord-006870-f5w6fw6q 5500 7 cerebral cerebral JJ cord-006870-f5w6fw6q 5500 8 artery artery NN cord-006870-f5w6fw6q 5500 9 embolism embolism NN cord-006870-f5w6fw6q 5500 10 ( ( -LRB- cord-006870-f5w6fw6q 5500 11 CAE CAE NNP cord-006870-f5w6fw6q 5500 12 ) ) -RRB- cord-006870-f5w6fw6q 5500 13 following follow VBG cord-006870-f5w6fw6q 5500 14 blunt blunt JJ cord-006870-f5w6fw6q 5500 15 trauma trauma NN cord-006870-f5w6fw6q 5500 16 . . . cord-006870-f5w6fw6q 5501 1 Case case NN cord-006870-f5w6fw6q 5501 2 Presentation presentation NN cord-006870-f5w6fw6q 5501 3 : : : cord-006870-f5w6fw6q 5502 1 A a DT cord-006870-f5w6fw6q 5502 2 49 49 CD cord-006870-f5w6fw6q 5502 3 year year NN cord-006870-f5w6fw6q 5502 4 - - HYPH cord-006870-f5w6fw6q 5502 5 old old JJ cord-006870-f5w6fw6q 5502 6 male male NN cord-006870-f5w6fw6q 5502 7 was be VBD cord-006870-f5w6fw6q 5502 8 admitted admit VBN cord-006870-f5w6fw6q 5502 9 with with IN cord-006870-f5w6fw6q 5502 10 a a DT cord-006870-f5w6fw6q 5502 11 right right JJ cord-006870-f5w6fw6q 5502 12 vertebral vertebral JJ cord-006870-f5w6fw6q 5502 13 artery artery NN cord-006870-f5w6fw6q 5502 14 dissection dissection NN cord-006870-f5w6fw6q 5502 15 and and CC cord-006870-f5w6fw6q 5502 16 occlusion occlusion NN cord-006870-f5w6fw6q 5502 17 with with IN cord-006870-f5w6fw6q 5502 18 intraluminal intraluminal JJ cord-006870-f5w6fw6q 5502 19 air air NN cord-006870-f5w6fw6q 5502 20 , , , cord-006870-f5w6fw6q 5502 21 widespread widespread JJ cord-006870-f5w6fw6q 5502 22 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5502 23 , , , cord-006870-f5w6fw6q 5502 24 bilateral bilateral JJ cord-006870-f5w6fw6q 5502 25 pneumothoraces pneumothorace NNS cord-006870-f5w6fw6q 5502 26 , , , cord-006870-f5w6fw6q 5502 27 a a DT cord-006870-f5w6fw6q 5502 28 pulmonary pulmonary JJ cord-006870-f5w6fw6q 5502 29 laceration laceration NN cord-006870-f5w6fw6q 5502 30 , , , cord-006870-f5w6fw6q 5502 31 and and CC cord-006870-f5w6fw6q 5502 32 multiple multiple JJ cord-006870-f5w6fw6q 5502 33 fractures fracture NNS cord-006870-f5w6fw6q 5502 34 including include VBG cord-006870-f5w6fw6q 5502 35 ribs rib NNS cord-006870-f5w6fw6q 5502 36 , , , cord-006870-f5w6fw6q 5502 37 C3 c3 JJ cord-006870-f5w6fw6q 5502 38 transverse transverse JJ cord-006870-f5w6fw6q 5502 39 foramen foramen NN cord-006870-f5w6fw6q 5502 40 ( ( -LRB- cord-006870-f5w6fw6q 5502 41 with with IN cord-006870-f5w6fw6q 5502 42 normal normal JJ cord-006870-f5w6fw6q 5502 43 alignment alignment NN cord-006870-f5w6fw6q 5502 44 ) ) -RRB- cord-006870-f5w6fw6q 5502 45 , , , cord-006870-f5w6fw6q 5502 46 and and CC cord-006870-f5w6fw6q 5502 47 femur femur NN cord-006870-f5w6fw6q 5502 48 following follow VBG cord-006870-f5w6fw6q 5502 49 a a DT cord-006870-f5w6fw6q 5502 50 motor motor NN cord-006870-f5w6fw6q 5502 51 vehicle vehicle NN cord-006870-f5w6fw6q 5502 52 collision collision NN cord-006870-f5w6fw6q 5502 53 . . . cord-006870-f5w6fw6q 5503 1 His -PRON- PRP$ cord-006870-f5w6fw6q 5503 2 pupils pupil NNS cord-006870-f5w6fw6q 5503 3 were be VBD cord-006870-f5w6fw6q 5503 4 initially initially RB cord-006870-f5w6fw6q 5503 5 nonreactive nonreactive JJ cord-006870-f5w6fw6q 5503 6 , , , cord-006870-f5w6fw6q 5503 7 and and CC cord-006870-f5w6fw6q 5503 8 he -PRON- PRP cord-006870-f5w6fw6q 5503 9 experienced experience VBD cord-006870-f5w6fw6q 5503 10 one one CD cord-006870-f5w6fw6q 5503 11 hour hour NN cord-006870-f5w6fw6q 5503 12 of of IN cord-006870-f5w6fw6q 5503 13 witnessed witness VBN cord-006870-f5w6fw6q 5503 14 generalized generalized JJ cord-006870-f5w6fw6q 5503 15 seizure seizure NN cord-006870-f5w6fw6q 5503 16 activity activity NN cord-006870-f5w6fw6q 5503 17 on on IN cord-006870-f5w6fw6q 5503 18 arrival arrival NN cord-006870-f5w6fw6q 5503 19 despite despite IN cord-006870-f5w6fw6q 5503 20 aggressive aggressive JJ cord-006870-f5w6fw6q 5503 21 treatment treatment NN cord-006870-f5w6fw6q 5503 22 . . . cord-006870-f5w6fw6q 5504 1 Management management NN cord-006870-f5w6fw6q 5504 2 : : : cord-006870-f5w6fw6q 5505 1 Midazolam Midazolam NNP cord-006870-f5w6fw6q 5505 2 infusion infusion NN cord-006870-f5w6fw6q 5505 3 , , , cord-006870-f5w6fw6q 5505 4 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 5505 5 , , , cord-006870-f5w6fw6q 5505 6 and and CC cord-006870-f5w6fw6q 5505 7 fosphenytoin fosphenytoin NNP cord-006870-f5w6fw6q 5505 8 were be VBD cord-006870-f5w6fw6q 5505 9 initiated initiate VBN cord-006870-f5w6fw6q 5505 10 for for IN cord-006870-f5w6fw6q 5505 11 seizure seizure NN cord-006870-f5w6fw6q 5505 12 control control NN cord-006870-f5w6fw6q 5505 13 . . . cord-006870-f5w6fw6q 5506 1 Targeted target VBN cord-006870-f5w6fw6q 5506 2 temperature temperature NN cord-006870-f5w6fw6q 5506 3 management management NN cord-006870-f5w6fw6q 5506 4 to to IN cord-006870-f5w6fw6q 5506 5 36 36 CD cord-006870-f5w6fw6q 5506 6 Celsius Celsius NNP cord-006870-f5w6fw6q 5506 7 was be VBD cord-006870-f5w6fw6q 5506 8 initiated initiate VBN cord-006870-f5w6fw6q 5506 9 on on IN cord-006870-f5w6fw6q 5506 10 arrival arrival NN cord-006870-f5w6fw6q 5506 11 out out IN cord-006870-f5w6fw6q 5506 12 of of IN cord-006870-f5w6fw6q 5506 13 concern concern NN cord-006870-f5w6fw6q 5506 14 for for IN cord-006870-f5w6fw6q 5506 15 hypoxic hypoxic JJ cord-006870-f5w6fw6q 5506 16 brain brain NN cord-006870-f5w6fw6q 5506 17 injury injury NN cord-006870-f5w6fw6q 5506 18 . . . cord-006870-f5w6fw6q 5507 1 Computed compute VBN cord-006870-f5w6fw6q 5507 2 tomography tomography NN cord-006870-f5w6fw6q 5507 3 at at IN cord-006870-f5w6fw6q 5507 4 12 12 CD cord-006870-f5w6fw6q 5507 5 hours hour NNS cord-006870-f5w6fw6q 5508 1 demonstrated demonstrate VBN cord-006870-f5w6fw6q 5508 2 resolution resolution NN cord-006870-f5w6fw6q 5508 3 of of IN cord-006870-f5w6fw6q 5508 4 vertebral vertebral JJ cord-006870-f5w6fw6q 5508 5 and and CC cord-006870-f5w6fw6q 5508 6 intracerebral intracerebral NNP cord-006870-f5w6fw6q 5508 7 air air NN cord-006870-f5w6fw6q 5508 8 , , , cord-006870-f5w6fw6q 5508 9 diffuse diffuse VB cord-006870-f5w6fw6q 5508 10 edema edema NN cord-006870-f5w6fw6q 5508 11 , , , cord-006870-f5w6fw6q 5508 12 and and CC cord-006870-f5w6fw6q 5508 13 diffuse diffuse VB cord-006870-f5w6fw6q 5508 14 loss loss NN cord-006870-f5w6fw6q 5508 15 of of IN cord-006870-f5w6fw6q 5508 16 gray gray JJ cord-006870-f5w6fw6q 5508 17 - - HYPH cord-006870-f5w6fw6q 5508 18 white white JJ cord-006870-f5w6fw6q 5508 19 matter matter NN cord-006870-f5w6fw6q 5508 20 differentiation differentiation NN cord-006870-f5w6fw6q 5508 21 , , , cord-006870-f5w6fw6q 5508 22 thus thus RB cord-006870-f5w6fw6q 5508 23 a a DT cord-006870-f5w6fw6q 5508 24 hypertonic hypertonic JJ cord-006870-f5w6fw6q 5508 25 saline saline NN cord-006870-f5w6fw6q 5508 26 infusion infusion NN cord-006870-f5w6fw6q 5508 27 was be VBD cord-006870-f5w6fw6q 5508 28 initiated initiate VBN cord-006870-f5w6fw6q 5508 29 . . . cord-006870-f5w6fw6q 5509 1 The the DT cord-006870-f5w6fw6q 5509 2 following following JJ cord-006870-f5w6fw6q 5509 3 day day NN cord-006870-f5w6fw6q 5509 4 , , , cord-006870-f5w6fw6q 5509 5 an an DT cord-006870-f5w6fw6q 5509 6 MRI MRI NNP cord-006870-f5w6fw6q 5509 7 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5509 8 diffusion diffusion NN cord-006870-f5w6fw6q 5509 9 restriction restriction NN cord-006870-f5w6fw6q 5509 10 in in IN cord-006870-f5w6fw6q 5509 11 the the DT cord-006870-f5w6fw6q 5509 12 areas area NNS cord-006870-f5w6fw6q 5509 13 adjacent adjacent JJ cord-006870-f5w6fw6q 5509 14 to to IN cord-006870-f5w6fw6q 5509 15 the the DT cord-006870-f5w6fw6q 5509 16 air air NN cord-006870-f5w6fw6q 5509 17 , , , cord-006870-f5w6fw6q 5509 18 including include VBG cord-006870-f5w6fw6q 5509 19 C3 C3 NNP cord-006870-f5w6fw6q 5509 20 - - SYM cord-006870-f5w6fw6q 5509 21 4 4 CD cord-006870-f5w6fw6q 5509 22 and and CC cord-006870-f5w6fw6q 5509 23 diffusely diffusely RB cord-006870-f5w6fw6q 5509 24 throughout throughout IN cord-006870-f5w6fw6q 5509 25 bilateral bilateral JJ cord-006870-f5w6fw6q 5509 26 cerebral cerebral JJ cord-006870-f5w6fw6q 5509 27 hemispheres hemisphere NNS cord-006870-f5w6fw6q 5509 28 . . . cord-006870-f5w6fw6q 5510 1 Prognosis prognosis NN cord-006870-f5w6fw6q 5510 2 was be VBD cord-006870-f5w6fw6q 5510 3 thought think VBN cord-006870-f5w6fw6q 5510 4 to to TO cord-006870-f5w6fw6q 5510 5 be be VB cord-006870-f5w6fw6q 5510 6 poor poor JJ cord-006870-f5w6fw6q 5510 7 . . . cord-006870-f5w6fw6q 5511 1 However however RB cord-006870-f5w6fw6q 5511 2 , , , cord-006870-f5w6fw6q 5511 3 the the DT cord-006870-f5w6fw6q 5511 4 following follow VBG cord-006870-f5w6fw6q 5511 5 day day NN cord-006870-f5w6fw6q 5511 6 , , , cord-006870-f5w6fw6q 5511 7 the the DT cord-006870-f5w6fw6q 5511 8 patient patient NN cord-006870-f5w6fw6q 5511 9 awoke awake VBD cord-006870-f5w6fw6q 5511 10 . . . cord-006870-f5w6fw6q 5512 1 By by IN cord-006870-f5w6fw6q 5512 2 day day NN cord-006870-f5w6fw6q 5512 3 four four CD cord-006870-f5w6fw6q 5512 4 he -PRON- PRP cord-006870-f5w6fw6q 5512 5 followed follow VBD cord-006870-f5w6fw6q 5512 6 commands command NNS cord-006870-f5w6fw6q 5512 7 . . . cord-006870-f5w6fw6q 5513 1 He -PRON- PRP cord-006870-f5w6fw6q 5513 2 was be VBD cord-006870-f5w6fw6q 5513 3 discharged discharge VBN cord-006870-f5w6fw6q 5513 4 to to IN cord-006870-f5w6fw6q 5513 5 skilled skilled JJ cord-006870-f5w6fw6q 5513 6 nursing nursing NN cord-006870-f5w6fw6q 5513 7 on on IN cord-006870-f5w6fw6q 5513 8 day day NN cord-006870-f5w6fw6q 5513 9 17 17 CD cord-006870-f5w6fw6q 5513 10 . . . cord-006870-f5w6fw6q 5514 1 At at IN cord-006870-f5w6fw6q 5514 2 three three CD cord-006870-f5w6fw6q 5514 3 months month NNS cord-006870-f5w6fw6q 5514 4 he -PRON- PRP cord-006870-f5w6fw6q 5514 5 had have VBD cord-006870-f5w6fw6q 5514 6 only only RB cord-006870-f5w6fw6q 5514 7 minimal minimal JJ cord-006870-f5w6fw6q 5514 8 residual residual JJ cord-006870-f5w6fw6q 5514 9 right right JJ cord-006870-f5w6fw6q 5514 10 hip hip NN cord-006870-f5w6fw6q 5514 11 weakness weakness NN cord-006870-f5w6fw6q 5514 12 . . . cord-006870-f5w6fw6q 5515 1 Discussion discussion NN cord-006870-f5w6fw6q 5515 2 : : : cord-006870-f5w6fw6q 5516 1 There there EX cord-006870-f5w6fw6q 5516 2 are be VBP cord-006870-f5w6fw6q 5516 3 only only RB cord-006870-f5w6fw6q 5516 4 three three CD cord-006870-f5w6fw6q 5516 5 case case NN cord-006870-f5w6fw6q 5516 6 reports report NNS cord-006870-f5w6fw6q 5516 7 of of IN cord-006870-f5w6fw6q 5516 8 CAE CAE NNP cord-006870-f5w6fw6q 5516 9 following follow VBG cord-006870-f5w6fw6q 5516 10 blunt blunt JJ cord-006870-f5w6fw6q 5516 11 trauma trauma NN cord-006870-f5w6fw6q 5516 12 , , , cord-006870-f5w6fw6q 5516 13 and and CC cord-006870-f5w6fw6q 5516 14 only only RB cord-006870-f5w6fw6q 5516 15 one one CD cord-006870-f5w6fw6q 5516 16 involving involve VBG cord-006870-f5w6fw6q 5516 17 the the DT cord-006870-f5w6fw6q 5516 18 vertebral vertebral JJ cord-006870-f5w6fw6q 5516 19 artery artery NN cord-006870-f5w6fw6q 5516 20 . . . cord-006870-f5w6fw6q 5517 1 Air air NN cord-006870-f5w6fw6q 5517 2 migrates migrate VBZ cord-006870-f5w6fw6q 5517 3 to to IN cord-006870-f5w6fw6q 5517 4 the the DT cord-006870-f5w6fw6q 5517 5 arterial arterial JJ cord-006870-f5w6fw6q 5517 6 circulation circulation NN cord-006870-f5w6fw6q 5517 7 due due IN cord-006870-f5w6fw6q 5517 8 to to IN cord-006870-f5w6fw6q 5517 9 a a DT cord-006870-f5w6fw6q 5517 10 positive positive JJ cord-006870-f5w6fw6q 5517 11 gradient gradient NN cord-006870-f5w6fw6q 5517 12 from from IN cord-006870-f5w6fw6q 5517 13 low low JJ cord-006870-f5w6fw6q 5517 14 central central JJ cord-006870-f5w6fw6q 5517 15 venous venous JJ cord-006870-f5w6fw6q 5517 16 pressure pressure NN cord-006870-f5w6fw6q 5517 17 or or CC cord-006870-f5w6fw6q 5517 18 high high JJ cord-006870-f5w6fw6q 5517 19 airway airway NN cord-006870-f5w6fw6q 5517 20 pressure pressure NN cord-006870-f5w6fw6q 5517 21 . . . cord-006870-f5w6fw6q 5518 1 Pulmonary pulmonary JJ cord-006870-f5w6fw6q 5518 2 venous venous JJ cord-006870-f5w6fw6q 5518 3 air air NN cord-006870-f5w6fw6q 5519 1 then then RB cord-006870-f5w6fw6q 5519 2 embolizes embolize VBZ cord-006870-f5w6fw6q 5519 3 to to IN cord-006870-f5w6fw6q 5519 4 cerebral cerebral JJ cord-006870-f5w6fw6q 5519 5 vasculature vasculature NN cord-006870-f5w6fw6q 5519 6 . . . cord-006870-f5w6fw6q 5520 1 As as RB cord-006870-f5w6fw6q 5520 2 little little JJ cord-006870-f5w6fw6q 5520 3 as as IN cord-006870-f5w6fw6q 5520 4 2mL 2ml CD cord-006870-f5w6fw6q 5520 5 of of IN cord-006870-f5w6fw6q 5520 6 arterial arterial JJ cord-006870-f5w6fw6q 5520 7 air air NN cord-006870-f5w6fw6q 5520 8 emboli embolus NNS cord-006870-f5w6fw6q 5520 9 can can MD cord-006870-f5w6fw6q 5520 10 be be VB cord-006870-f5w6fw6q 5520 11 fatal fatal JJ cord-006870-f5w6fw6q 5520 12 with with IN cord-006870-f5w6fw6q 5520 13 the the DT cord-006870-f5w6fw6q 5520 14 major major JJ cord-006870-f5w6fw6q 5520 15 cause cause NN cord-006870-f5w6fw6q 5520 16 of of IN cord-006870-f5w6fw6q 5520 17 death death NN cord-006870-f5w6fw6q 5520 18 being be VBG cord-006870-f5w6fw6q 5520 19 circulatory circulatory JJ cord-006870-f5w6fw6q 5520 20 obstruction obstruction NN cord-006870-f5w6fw6q 5520 21 and and CC cord-006870-f5w6fw6q 5520 22 arrest arrest NN cord-006870-f5w6fw6q 5520 23 from from IN cord-006870-f5w6fw6q 5520 24 air air NN cord-006870-f5w6fw6q 5520 25 trapped trap VBN cord-006870-f5w6fw6q 5520 26 in in IN cord-006870-f5w6fw6q 5520 27 the the DT cord-006870-f5w6fw6q 5520 28 right right JJ cord-006870-f5w6fw6q 5520 29 ventricular ventricular JJ cord-006870-f5w6fw6q 5520 30 outflow outflow JJ cord-006870-f5w6fw6q 5520 31 tract tract NN cord-006870-f5w6fw6q 5520 32 . . . cord-006870-f5w6fw6q 5521 1 Conclusion conclusion NN cord-006870-f5w6fw6q 5521 2 : : : cord-006870-f5w6fw6q 5522 1 This this DT cord-006870-f5w6fw6q 5522 2 patient patient NN cord-006870-f5w6fw6q 5522 3 developed develop VBD cord-006870-f5w6fw6q 5522 4 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5522 5 and and CC cord-006870-f5w6fw6q 5522 6 CAE CAE NNP cord-006870-f5w6fw6q 5522 7 due due IN cord-006870-f5w6fw6q 5522 8 to to IN cord-006870-f5w6fw6q 5522 9 a a DT cord-006870-f5w6fw6q 5522 10 pulmonary pulmonary JJ cord-006870-f5w6fw6q 5522 11 laceration laceration NN cord-006870-f5w6fw6q 5522 12 . . . cord-006870-f5w6fw6q 5523 1 As as IN cord-006870-f5w6fw6q 5523 2 the the DT cord-006870-f5w6fw6q 5523 3 cerebral cerebral JJ cord-006870-f5w6fw6q 5523 4 air air NN cord-006870-f5w6fw6q 5523 5 reabsorbed reabsorb VBN cord-006870-f5w6fw6q 5523 6 , , , cord-006870-f5w6fw6q 5523 7 his -PRON- PRP$ cord-006870-f5w6fw6q 5523 8 seizures seizure NNS cord-006870-f5w6fw6q 5523 9 resolved resolve VBN cord-006870-f5w6fw6q 5523 10 and and CC cord-006870-f5w6fw6q 5523 11 his -PRON- PRP$ cord-006870-f5w6fw6q 5523 12 exam exam NN cord-006870-f5w6fw6q 5523 13 improved improve VBD cord-006870-f5w6fw6q 5523 14 . . . cord-006870-f5w6fw6q 5524 1 Petrous petrous JJ cord-006870-f5w6fw6q 5524 2 ICA ICA NNP cord-006870-f5w6fw6q 5524 3 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5524 4 are be VBP cord-006870-f5w6fw6q 5524 5 extremely extremely RB cord-006870-f5w6fw6q 5524 6 rare1 rare1 NN cord-006870-f5w6fw6q 5524 7 - - HYPH cord-006870-f5w6fw6q 5524 8 2 2 CD cord-006870-f5w6fw6q 5524 9 and and CC cord-006870-f5w6fw6q 5524 10 difficult difficult JJ cord-006870-f5w6fw6q 5524 11 to to TO cord-006870-f5w6fw6q 5524 12 treat treat VB cord-006870-f5w6fw6q 5524 13 surgically surgically RB cord-006870-f5w6fw6q 5524 14 , , , cord-006870-f5w6fw6q 5524 15 due due IN cord-006870-f5w6fw6q 5524 16 to to IN cord-006870-f5w6fw6q 5524 17 the the DT cord-006870-f5w6fw6q 5524 18 inherent inherent JJ cord-006870-f5w6fw6q 5524 19 challenges challenge NNS cord-006870-f5w6fw6q 5524 20 of of IN cord-006870-f5w6fw6q 5524 21 microsurgical microsurgical JJ cord-006870-f5w6fw6q 5524 22 access access NN cord-006870-f5w6fw6q 5524 23 to to IN cord-006870-f5w6fw6q 5524 24 the the DT cord-006870-f5w6fw6q 5524 25 carotid carotid JJ cord-006870-f5w6fw6q 5524 26 canal canal NN cord-006870-f5w6fw6q 5524 27 of of IN cord-006870-f5w6fw6q 5524 28 the the DT cord-006870-f5w6fw6q 5524 29 petrous petrous JJ cord-006870-f5w6fw6q 5524 30 bone3 bone3 NNP cord-006870-f5w6fw6q 5524 31 - - HYPH cord-006870-f5w6fw6q 5524 32 4 4 CD cord-006870-f5w6fw6q 5524 33 . . . cord-006870-f5w6fw6q 5525 1 Endovascular endovascular JJ cord-006870-f5w6fw6q 5525 2 approaches approach NNS cord-006870-f5w6fw6q 5525 3 may may MD cord-006870-f5w6fw6q 5525 4 also also RB cord-006870-f5w6fw6q 5525 5 prove prove VB cord-006870-f5w6fw6q 5525 6 challenging challenging JJ cord-006870-f5w6fw6q 5525 7 , , , cord-006870-f5w6fw6q 5525 8 typically typically RB cord-006870-f5w6fw6q 5525 9 as as IN cord-006870-f5w6fw6q 5525 10 the the DT cord-006870-f5w6fw6q 5525 11 consequence consequence NN cord-006870-f5w6fw6q 5525 12 of of IN cord-006870-f5w6fw6q 5525 13 therapeutically therapeutically RB cord-006870-f5w6fw6q 5525 14 - - HYPH cord-006870-f5w6fw6q 5525 15 unamenable unamenable JJ cord-006870-f5w6fw6q 5525 16 morphology morphology NN cord-006870-f5w6fw6q 5525 17 , , , cord-006870-f5w6fw6q 5525 18 but but CC cord-006870-f5w6fw6q 5525 19 occasionally occasionally RB cord-006870-f5w6fw6q 5525 20 due due IN cord-006870-f5w6fw6q 5525 21 to to IN cord-006870-f5w6fw6q 5525 22 size size NN cord-006870-f5w6fw6q 5525 23 considerations consideration NNS cord-006870-f5w6fw6q 5525 24 as as IN cord-006870-f5w6fw6q 5525 25 well.5 well.5 NNP cord-006870-f5w6fw6q 5525 26 A a DT cord-006870-f5w6fw6q 5525 27 23-year 23-year JJ cord-006870-f5w6fw6q 5525 28 - - HYPH cord-006870-f5w6fw6q 5525 29 old old JJ cord-006870-f5w6fw6q 5525 30 male male NN cord-006870-f5w6fw6q 5525 31 presented present VBN cord-006870-f5w6fw6q 5525 32 with with IN cord-006870-f5w6fw6q 5525 33 headache headache NN cord-006870-f5w6fw6q 5525 34 and and CC cord-006870-f5w6fw6q 5525 35 vertigo vertigo NN cord-006870-f5w6fw6q 5525 36 for for IN cord-006870-f5w6fw6q 5525 37 the the DT cord-006870-f5w6fw6q 5525 38 past past JJ cord-006870-f5w6fw6q 5525 39 3 3 CD cord-006870-f5w6fw6q 5525 40 weeks week NNS cord-006870-f5w6fw6q 5525 41 . . . cord-006870-f5w6fw6q 5526 1 The the DT cord-006870-f5w6fw6q 5526 2 patient patient NN cord-006870-f5w6fw6q 5526 3 was be VBD cord-006870-f5w6fw6q 5526 4 HIVpositive HIVpositive NNS cord-006870-f5w6fw6q 5526 5 with with IN cord-006870-f5w6fw6q 5526 6 medication medication NN cord-006870-f5w6fw6q 5526 7 noncompliance noncompliance NN cord-006870-f5w6fw6q 5526 8 and and CC cord-006870-f5w6fw6q 5526 9 denied deny VBD cord-006870-f5w6fw6q 5526 10 any any DT cord-006870-f5w6fw6q 5526 11 history history NN cord-006870-f5w6fw6q 5526 12 of of IN cord-006870-f5w6fw6q 5526 13 trauma trauma NN cord-006870-f5w6fw6q 5526 14 or or CC cord-006870-f5w6fw6q 5526 15 head head NN cord-006870-f5w6fw6q 5526 16 injury injury NN cord-006870-f5w6fw6q 5526 17 . . . cord-006870-f5w6fw6q 5527 1 Head Head NNP cord-006870-f5w6fw6q 5527 2 CT CT NNP cord-006870-f5w6fw6q 5527 3 identified identify VBD cord-006870-f5w6fw6q 5527 4 a a DT cord-006870-f5w6fw6q 5527 5 3.9 3.9 CD cord-006870-f5w6fw6q 5527 6 x x SYM cord-006870-f5w6fw6q 5527 7 2.3 2.3 CD cord-006870-f5w6fw6q 5527 8 cm cm VBP cord-006870-f5w6fw6q 5527 9 heterogeneous heterogeneous JJ cord-006870-f5w6fw6q 5527 10 soft soft JJ cord-006870-f5w6fw6q 5527 11 tissue tissue NN cord-006870-f5w6fw6q 5527 12 density density NN cord-006870-f5w6fw6q 5527 13 lesion lesion NN cord-006870-f5w6fw6q 5527 14 in in IN cord-006870-f5w6fw6q 5527 15 the the DT cord-006870-f5w6fw6q 5527 16 right right JJ cord-006870-f5w6fw6q 5527 17 petrous petrous JJ cord-006870-f5w6fw6q 5527 18 bone bone NN cord-006870-f5w6fw6q 5527 19 . . . cord-006870-f5w6fw6q 5528 1 CT CT NNP cord-006870-f5w6fw6q 5528 2 angiography angiography NN cord-006870-f5w6fw6q 5528 3 revealed reveal VBD cord-006870-f5w6fw6q 5528 4 a a DT cord-006870-f5w6fw6q 5528 5 3.0 3.0 CD cord-006870-f5w6fw6q 5528 6 x x SYM cord-006870-f5w6fw6q 5528 7 1.8 1.8 CD cord-006870-f5w6fw6q 5528 8 x x SYM cord-006870-f5w6fw6q 5528 9 2.8 2.8 CD cord-006870-f5w6fw6q 5528 10 cm cm NNS cord-006870-f5w6fw6q 5528 11 lobulated lobulate VBN cord-006870-f5w6fw6q 5528 12 giant giant JJ cord-006870-f5w6fw6q 5528 13 aneurysm aneurysm NN cord-006870-f5w6fw6q 5528 14 of of IN cord-006870-f5w6fw6q 5528 15 the the DT cord-006870-f5w6fw6q 5528 16 right right JJ cord-006870-f5w6fw6q 5528 17 petrous petrous JJ cord-006870-f5w6fw6q 5528 18 ICA ICA NNP cord-006870-f5w6fw6q 5528 19 . . . cord-006870-f5w6fw6q 5529 1 MRI MRI NNP cord-006870-f5w6fw6q 5529 2 / / SYM cord-006870-f5w6fw6q 5529 3 MRA MRA NNP cord-006870-f5w6fw6q 5529 4 was be VBD cord-006870-f5w6fw6q 5529 5 performed perform VBN cord-006870-f5w6fw6q 5529 6 to to TO cord-006870-f5w6fw6q 5529 7 rule rule VB cord-006870-f5w6fw6q 5529 8 out out RP cord-006870-f5w6fw6q 5529 9 thrombosis thrombosis NN cord-006870-f5w6fw6q 5529 10 and and CC cord-006870-f5w6fw6q 5529 11 showed show VBD cord-006870-f5w6fw6q 5529 12 giant giant NN cord-006870-f5w6fw6q 5529 13 partially partially RB cord-006870-f5w6fw6q 5529 14 thrombosed thrombosed JJ cord-006870-f5w6fw6q 5530 1 right right NNP cord-006870-f5w6fw6q 5530 2 petrous petrous NNP cord-006870-f5w6fw6q 5531 1 ICA ICA NNP cord-006870-f5w6fw6q 5531 2 aneurysm aneurysm NNP cord-006870-f5w6fw6q 5531 3 . . . cord-006870-f5w6fw6q 5532 1 The the DT cord-006870-f5w6fw6q 5532 2 decision decision NN cord-006870-f5w6fw6q 5532 3 was be VBD cord-006870-f5w6fw6q 5532 4 made make VBN cord-006870-f5w6fw6q 5532 5 to to TO cord-006870-f5w6fw6q 5532 6 treat treat VB cord-006870-f5w6fw6q 5532 7 using use VBG cord-006870-f5w6fw6q 5532 8 flow flow NN cord-006870-f5w6fw6q 5532 9 diversion diversion NN cord-006870-f5w6fw6q 5532 10 . . . cord-006870-f5w6fw6q 5533 1 The the DT cord-006870-f5w6fw6q 5533 2 patient patient NN cord-006870-f5w6fw6q 5533 3 underwent undergo VBD cord-006870-f5w6fw6q 5533 4 catheter catheter NN cord-006870-f5w6fw6q 5533 5 angiography angiography NN cord-006870-f5w6fw6q 5533 6 , , , cord-006870-f5w6fw6q 5533 7 confirming confirm VBG cord-006870-f5w6fw6q 5533 8 a a DT cord-006870-f5w6fw6q 5533 9 giant giant JJ cord-006870-f5w6fw6q 5533 10 3 3 CD cord-006870-f5w6fw6q 5533 11 x x SYM cord-006870-f5w6fw6q 5533 12 3.5 3.5 CD cord-006870-f5w6fw6q 5533 13 cm cm NN cord-006870-f5w6fw6q 5533 14 right right JJ cord-006870-f5w6fw6q 5533 15 internal internal JJ cord-006870-f5w6fw6q 5533 16 carotid carotid JJ cord-006870-f5w6fw6q 5533 17 artery artery NN cord-006870-f5w6fw6q 5533 18 petrous petrous JJ cord-006870-f5w6fw6q 5533 19 segment segment NN cord-006870-f5w6fw6q 5533 20 aneurysm aneurysm NNP cord-006870-f5w6fw6q 5533 21 . . . cord-006870-f5w6fw6q 5534 1 We -PRON- PRP cord-006870-f5w6fw6q 5534 2 proceeded proceed VBD cord-006870-f5w6fw6q 5534 3 with with IN cord-006870-f5w6fw6q 5534 4 flow flow NN cord-006870-f5w6fw6q 5534 5 diversion diversion NN cord-006870-f5w6fw6q 5534 6 pipeline pipeline NN cord-006870-f5w6fw6q 5534 7 endovascular endovascular NN cord-006870-f5w6fw6q 5534 8 device device NN cord-006870-f5w6fw6q 5534 9 , , , cord-006870-f5w6fw6q 5534 10 placement placement NN cord-006870-f5w6fw6q 5534 11 of of IN cord-006870-f5w6fw6q 5534 12 two two CD cord-006870-f5w6fw6q 5534 13 pipeline pipeline NN cord-006870-f5w6fw6q 5534 14 endovascular endovascular JJ cord-006870-f5w6fw6q 5534 15 devices device NNS cord-006870-f5w6fw6q 5534 16 ( ( -LRB- cord-006870-f5w6fw6q 5534 17 flex flex NNP cord-006870-f5w6fw6q 5534 18 5 5 CD cord-006870-f5w6fw6q 5534 19 x x SYM cord-006870-f5w6fw6q 5534 20 30 30 CD cord-006870-f5w6fw6q 5534 21 and and CC cord-006870-f5w6fw6q 5534 22 5 5 CD cord-006870-f5w6fw6q 5534 23 x x SYM cord-006870-f5w6fw6q 5534 24 25 25 CD cord-006870-f5w6fw6q 5534 25 ) ) -RRB- cord-006870-f5w6fw6q 5534 26 successfully successfully RB cord-006870-f5w6fw6q 5534 27 . . . cord-006870-f5w6fw6q 5535 1 Final final JJ cord-006870-f5w6fw6q 5535 2 angiographic angiographic JJ cord-006870-f5w6fw6q 5535 3 runs run NNS cord-006870-f5w6fw6q 5535 4 showed show VBD cord-006870-f5w6fw6q 5535 5 significant significant JJ cord-006870-f5w6fw6q 5535 6 stasis stasis NN cord-006870-f5w6fw6q 5535 7 within within IN cord-006870-f5w6fw6q 5535 8 the the DT cord-006870-f5w6fw6q 5535 9 aneurysm aneurysm NN cord-006870-f5w6fw6q 5535 10 and and CC cord-006870-f5w6fw6q 5535 11 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5535 12 the the DT cord-006870-f5w6fw6q 5535 13 flow flow NN cord-006870-f5w6fw6q 5535 14 - - HYPH cord-006870-f5w6fw6q 5535 15 diverter diverter NN cord-006870-f5w6fw6q 5535 16 construct construct NN cord-006870-f5w6fw6q 5535 17 was be VBD cord-006870-f5w6fw6q 5535 18 well well RB cord-006870-f5w6fw6q 5535 19 placed place VBN cord-006870-f5w6fw6q 5535 20 both both CC cord-006870-f5w6fw6q 5535 21 proximal proximal JJ cord-006870-f5w6fw6q 5535 22 and and CC cord-006870-f5w6fw6q 5535 23 distal distal JJ cord-006870-f5w6fw6q 5535 24 to to IN cord-006870-f5w6fw6q 5535 25 the the DT cord-006870-f5w6fw6q 5535 26 aneurysm aneurysm NN cord-006870-f5w6fw6q 5535 27 neck neck NN cord-006870-f5w6fw6q 5535 28 with with IN cord-006870-f5w6fw6q 5535 29 no no DT cord-006870-f5w6fw6q 5535 30 sign sign NN cord-006870-f5w6fw6q 5535 31 of of IN cord-006870-f5w6fw6q 5535 32 endovascular endovascular JJ cord-006870-f5w6fw6q 5535 33 leak leak NN cord-006870-f5w6fw6q 5535 34 . . . cord-006870-f5w6fw6q 5536 1 The the DT cord-006870-f5w6fw6q 5536 2 patient patient NN cord-006870-f5w6fw6q 5536 3 was be VBD cord-006870-f5w6fw6q 5536 4 discharged discharge VBN cord-006870-f5w6fw6q 5536 5 home home RB cord-006870-f5w6fw6q 5536 6 well well RB cord-006870-f5w6fw6q 5536 7 . . . cord-006870-f5w6fw6q 5537 1 We -PRON- PRP cord-006870-f5w6fw6q 5537 2 suggest suggest VBP cord-006870-f5w6fw6q 5537 3 that that IN cord-006870-f5w6fw6q 5537 4 flow flow NN cord-006870-f5w6fw6q 5537 5 diversion diversion NN cord-006870-f5w6fw6q 5537 6 is be VBZ cord-006870-f5w6fw6q 5537 7 an an DT cord-006870-f5w6fw6q 5537 8 ideal ideal JJ cord-006870-f5w6fw6q 5537 9 treatment treatment NN cord-006870-f5w6fw6q 5537 10 for for IN cord-006870-f5w6fw6q 5537 11 petrous petrous JJ cord-006870-f5w6fw6q 5537 12 ICA ICA NNP cord-006870-f5w6fw6q 5537 13 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5537 14 , , , cord-006870-f5w6fw6q 5537 15 specifically specifically RB cord-006870-f5w6fw6q 5537 16 un un JJ cord-006870-f5w6fw6q 5537 17 - - JJ cord-006870-f5w6fw6q 5537 18 ruptured ruptured JJ cord-006870-f5w6fw6q 5537 19 lesions lesion NNS cord-006870-f5w6fw6q 5537 20 of of IN cord-006870-f5w6fw6q 5537 21 complex complex JJ cord-006870-f5w6fw6q 5537 22 morphology morphology NN cord-006870-f5w6fw6q 5537 23 . . . cord-006870-f5w6fw6q 5538 1 Other other JJ cord-006870-f5w6fw6q 5538 2 options option NNS cord-006870-f5w6fw6q 5538 3 for for IN cord-006870-f5w6fw6q 5538 4 treating treat VBG cord-006870-f5w6fw6q 5538 5 petrous petrous JJ cord-006870-f5w6fw6q 5538 6 ICA ICA NNP cord-006870-f5w6fw6q 5538 7 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5538 8 challenging challenge VBG cord-006870-f5w6fw6q 5538 9 , , , cord-006870-f5w6fw6q 5538 10 not not RB cord-006870-f5w6fw6q 5538 11 possible possible JJ cord-006870-f5w6fw6q 5538 12 , , , cord-006870-f5w6fw6q 5538 13 less less RBR cord-006870-f5w6fw6q 5538 14 effective effective JJ cord-006870-f5w6fw6q 5538 15 , , , cord-006870-f5w6fw6q 5538 16 and/or and/or CC cord-006870-f5w6fw6q 5538 17 carry carry VB cord-006870-f5w6fw6q 5538 18 substantial substantial JJ cord-006870-f5w6fw6q 5538 19 risks risk NNS cord-006870-f5w6fw6q 5538 20 . . . cord-006870-f5w6fw6q 5539 1 Second second RB cord-006870-f5w6fw6q 5539 2 , , , cord-006870-f5w6fw6q 5539 3 several several JJ cord-006870-f5w6fw6q 5539 4 of of IN cord-006870-f5w6fw6q 5539 5 the the DT cord-006870-f5w6fw6q 5539 6 disadvantages disadvantage NNS cord-006870-f5w6fw6q 5539 7 of of IN cord-006870-f5w6fw6q 5539 8 PEDocclusion pedocclusion NN cord-006870-f5w6fw6q 5539 9 of of IN cord-006870-f5w6fw6q 5539 10 side side JJ cord-006870-f5w6fw6q 5539 11 vessel vessel NN cord-006870-f5w6fw6q 5539 12 branches branch NNS cord-006870-f5w6fw6q 5539 13 and and CC cord-006870-f5w6fw6q 5539 14 preclusion preclusion NN cord-006870-f5w6fw6q 5539 15 of of IN cord-006870-f5w6fw6q 5539 16 future future JJ cord-006870-f5w6fw6q 5539 17 coil coil NN cord-006870-f5w6fw6q 5539 18 embolization embolization NN cord-006870-f5w6fw6q 5539 19 , , , cord-006870-f5w6fw6q 5539 20 do do VBP cord-006870-f5w6fw6q 5539 21 not not RB cord-006870-f5w6fw6q 5539 22 apply apply VB cord-006870-f5w6fw6q 5539 23 to to IN cord-006870-f5w6fw6q 5539 24 the the DT cord-006870-f5w6fw6q 5539 25 petrous petrous JJ cord-006870-f5w6fw6q 5539 26 segment segment NN cord-006870-f5w6fw6q 5539 27 of of IN cord-006870-f5w6fw6q 5539 28 the the DT cord-006870-f5w6fw6q 5539 29 ICA ICA NNP cord-006870-f5w6fw6q 5539 30 . . . cord-006870-f5w6fw6q 5540 1 Lastly lastly RB cord-006870-f5w6fw6q 5540 2 , , , cord-006870-f5w6fw6q 5540 3 use use NN cord-006870-f5w6fw6q 5540 4 of of IN cord-006870-f5w6fw6q 5540 5 PED PED NNP cord-006870-f5w6fw6q 5540 6 in in IN cord-006870-f5w6fw6q 5540 7 petrous petrous JJ cord-006870-f5w6fw6q 5540 8 ICA ICA NNP cord-006870-f5w6fw6q 5540 9 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5540 10 has have VBZ cord-006870-f5w6fw6q 5540 11 proven prove VBN cord-006870-f5w6fw6q 5540 12 effective effective JJ cord-006870-f5w6fw6q 5540 13 in in IN cord-006870-f5w6fw6q 5540 14 the the DT cord-006870-f5w6fw6q 5540 15 vast vast JJ cord-006870-f5w6fw6q 5540 16 majority majority NN cord-006870-f5w6fw6q 5540 17 of of IN cord-006870-f5w6fw6q 5540 18 reports report NNS cord-006870-f5w6fw6q 5540 19 . . . cord-006870-f5w6fw6q 5541 1 The the DT cord-006870-f5w6fw6q 5541 2 spot spot NN cord-006870-f5w6fw6q 5541 3 sign sign NN cord-006870-f5w6fw6q 5541 4 is be VBZ cord-006870-f5w6fw6q 5541 5 a a DT cord-006870-f5w6fw6q 5541 6 focus focus NN cord-006870-f5w6fw6q 5541 7 of of IN cord-006870-f5w6fw6q 5541 8 enhancement enhancement NN cord-006870-f5w6fw6q 5541 9 within within IN cord-006870-f5w6fw6q 5541 10 the the DT cord-006870-f5w6fw6q 5541 11 hematoma hematoma NN cord-006870-f5w6fw6q 5541 12 on on IN cord-006870-f5w6fw6q 5541 13 CT CT NNP cord-006870-f5w6fw6q 5541 14 angiogram angiogram NN cord-006870-f5w6fw6q 5541 15 ( ( -LRB- cord-006870-f5w6fw6q 5541 16 CTA CTA NNP cord-006870-f5w6fw6q 5541 17 ) ) -RRB- cord-006870-f5w6fw6q 5541 18 with with IN cord-006870-f5w6fw6q 5541 19 unique unique JJ cord-006870-f5w6fw6q 5541 20 characteristics characteristic NNS cord-006870-f5w6fw6q 5541 21 . . . cord-006870-f5w6fw6q 5542 1 It -PRON- PRP cord-006870-f5w6fw6q 5542 2 has have VBZ cord-006870-f5w6fw6q 5542 3 a a DT cord-006870-f5w6fw6q 5542 4 spot spot NN cord-006870-f5w6fw6q 5542 5 - - HYPH cord-006870-f5w6fw6q 5542 6 like like JJ cord-006870-f5w6fw6q 5542 7 appearance appearance NN cord-006870-f5w6fw6q 5542 8 within within IN cord-006870-f5w6fw6q 5542 9 the the DT cord-006870-f5w6fw6q 5542 10 margin margin NN cord-006870-f5w6fw6q 5542 11 of of IN cord-006870-f5w6fw6q 5542 12 a a DT cord-006870-f5w6fw6q 5542 13 parenchymal parenchymal JJ cord-006870-f5w6fw6q 5542 14 hematoma hematoma NN cord-006870-f5w6fw6q 5542 15 without without IN cord-006870-f5w6fw6q 5542 16 connection connection NN cord-006870-f5w6fw6q 5542 17 to to IN cord-006870-f5w6fw6q 5542 18 an an DT cord-006870-f5w6fw6q 5542 19 outside outside JJ cord-006870-f5w6fw6q 5542 20 vessel vessel NN cord-006870-f5w6fw6q 5542 21 . . . cord-006870-f5w6fw6q 5543 1 It -PRON- PRP cord-006870-f5w6fw6q 5543 2 should should MD cord-006870-f5w6fw6q 5543 3 measure measure VB cord-006870-f5w6fw6q 5543 4 greater great JJR cord-006870-f5w6fw6q 5543 5 than than IN cord-006870-f5w6fw6q 5543 6 1.5 1.5 CD cord-006870-f5w6fw6q 5543 7 mm mm NNS cord-006870-f5w6fw6q 5543 8 in in IN cord-006870-f5w6fw6q 5543 9 diameter diameter NN cord-006870-f5w6fw6q 5543 10 in in IN cord-006870-f5w6fw6q 5543 11 at at RB cord-006870-f5w6fw6q 5543 12 least least RBS cord-006870-f5w6fw6q 5543 13 one one CD cord-006870-f5w6fw6q 5543 14 dimension dimension NN cord-006870-f5w6fw6q 5543 15 . . . cord-006870-f5w6fw6q 5544 1 Its -PRON- PRP$ cord-006870-f5w6fw6q 5544 2 contrast contrast NN cord-006870-f5w6fw6q 5544 3 density density NN cord-006870-f5w6fw6q 5544 4 ( ( -LRB- cord-006870-f5w6fw6q 5544 5 Hounsfield Hounsfield NNP cord-006870-f5w6fw6q 5544 6 units unit NNS cord-006870-f5w6fw6q 5544 7 , , , cord-006870-f5w6fw6q 5544 8 HU HU NNP cord-006870-f5w6fw6q 5544 9 ) ) -RRB- cord-006870-f5w6fw6q 5544 10 is be VBZ cord-006870-f5w6fw6q 5544 11 at at IN cord-006870-f5w6fw6q 5544 12 least least JJS cord-006870-f5w6fw6q 5544 13 double double PDT cord-006870-f5w6fw6q 5544 14 that that DT cord-006870-f5w6fw6q 5544 15 of of IN cord-006870-f5w6fw6q 5544 16 the the DT cord-006870-f5w6fw6q 5544 17 background background NN cord-006870-f5w6fw6q 5544 18 hematoma hematoma NN cord-006870-f5w6fw6q 5544 19 . . . cord-006870-f5w6fw6q 5545 1 Finally finally RB cord-006870-f5w6fw6q 5545 2 , , , cord-006870-f5w6fw6q 5545 3 there there EX cord-006870-f5w6fw6q 5545 4 should should MD cord-006870-f5w6fw6q 5545 5 be be VB cord-006870-f5w6fw6q 5545 6 no no DT cord-006870-f5w6fw6q 5545 7 hyperdensity hyperdensity NN cord-006870-f5w6fw6q 5545 8 at at IN cord-006870-f5w6fw6q 5545 9 the the DT cord-006870-f5w6fw6q 5545 10 corresponding correspond VBG cord-006870-f5w6fw6q 5545 11 location location NN cord-006870-f5w6fw6q 5545 12 on on IN cord-006870-f5w6fw6q 5545 13 non non JJ cord-006870-f5w6fw6q 5545 14 - - JJ cord-006870-f5w6fw6q 5545 15 contrast contrast JJ cord-006870-f5w6fw6q 5545 16 CT CT NNP cord-006870-f5w6fw6q 5545 17 . . . cord-006870-f5w6fw6q 5546 1 It -PRON- PRP cord-006870-f5w6fw6q 5546 2 is be VBZ cord-006870-f5w6fw6q 5546 3 a a DT cord-006870-f5w6fw6q 5546 4 strong strong JJ cord-006870-f5w6fw6q 5546 5 predictor predictor NN cord-006870-f5w6fw6q 5546 6 of of IN cord-006870-f5w6fw6q 5546 7 hematoma hematoma NN cord-006870-f5w6fw6q 5546 8 expansion expansion NN cord-006870-f5w6fw6q 5546 9 and and CC cord-006870-f5w6fw6q 5546 10 poor poor JJ cord-006870-f5w6fw6q 5546 11 prognosis prognosis NN cord-006870-f5w6fw6q 5546 12 in in IN cord-006870-f5w6fw6q 5546 13 intra intra JJ cord-006870-f5w6fw6q 5546 14 - - JJ cord-006870-f5w6fw6q 5546 15 parenchymal parenchymal JJ cord-006870-f5w6fw6q 5546 16 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5546 17 . . . cord-006870-f5w6fw6q 5547 1 The the DT cord-006870-f5w6fw6q 5547 2 pathogenesis pathogenesis NN cord-006870-f5w6fw6q 5547 3 of of IN cord-006870-f5w6fw6q 5547 4 spot spot NN cord-006870-f5w6fw6q 5547 5 sign sign NN cord-006870-f5w6fw6q 5547 6 remains remain VBZ cord-006870-f5w6fw6q 5547 7 unclear unclear JJ cord-006870-f5w6fw6q 5547 8 . . . cord-006870-f5w6fw6q 5548 1 Some some DT cord-006870-f5w6fw6q 5548 2 studies study NNS cord-006870-f5w6fw6q 5548 3 showed show VBD cord-006870-f5w6fw6q 5548 4 an an DT cord-006870-f5w6fw6q 5548 5 association association NN cord-006870-f5w6fw6q 5548 6 with with IN cord-006870-f5w6fw6q 5548 7 faster fast JJR cord-006870-f5w6fw6q 5548 8 rates rate NNS cord-006870-f5w6fw6q 5548 9 of of IN cord-006870-f5w6fw6q 5548 10 contrast contrast NN cord-006870-f5w6fw6q 5548 11 leakage leakage NN cord-006870-f5w6fw6q 5548 12 which which WDT cord-006870-f5w6fw6q 5548 13 indicates indicate VBZ cord-006870-f5w6fw6q 5548 14 continued continue VBN cord-006870-f5w6fw6q 5548 15 bleeding bleed VBG cord-006870-f5w6fw6q 5548 16 . . . cord-006870-f5w6fw6q 5549 1 A a DT cord-006870-f5w6fw6q 5549 2 spot spot NN cord-006870-f5w6fw6q 5549 3 sign sign NN cord-006870-f5w6fw6q 5549 4 has have VBZ cord-006870-f5w6fw6q 5549 5 not not RB cord-006870-f5w6fw6q 5549 6 been be VBN cord-006870-f5w6fw6q 5549 7 reported report VBN cord-006870-f5w6fw6q 5549 8 with with IN cord-006870-f5w6fw6q 5549 9 isolated isolate VBN cord-006870-f5w6fw6q 5549 10 intraventricular intraventricular JJ cord-006870-f5w6fw6q 5549 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5549 12 ( ( -LRB- cord-006870-f5w6fw6q 5549 13 IVH IVH NNP cord-006870-f5w6fw6q 5549 14 ) ) -RRB- cord-006870-f5w6fw6q 5549 15 before before RB cord-006870-f5w6fw6q 5549 16 . . . cord-006870-f5w6fw6q 5550 1 A a DT cord-006870-f5w6fw6q 5550 2 case case NN cord-006870-f5w6fw6q 5550 3 report report NN cord-006870-f5w6fw6q 5550 4 of of IN cord-006870-f5w6fw6q 5550 5 a a DT cord-006870-f5w6fw6q 5550 6 59-year 59-year JJ cord-006870-f5w6fw6q 5550 7 - - HYPH cord-006870-f5w6fw6q 5550 8 old old JJ cord-006870-f5w6fw6q 5550 9 man man NN cord-006870-f5w6fw6q 5550 10 with with IN cord-006870-f5w6fw6q 5550 11 a a DT cord-006870-f5w6fw6q 5550 12 past past JJ cord-006870-f5w6fw6q 5550 13 medical medical JJ cord-006870-f5w6fw6q 5550 14 history history NN cord-006870-f5w6fw6q 5550 15 of of IN cord-006870-f5w6fw6q 5550 16 hypertension hypertension NN cord-006870-f5w6fw6q 5550 17 who who WP cord-006870-f5w6fw6q 5550 18 got get VBD cord-006870-f5w6fw6q 5550 19 admitted admit VBN cord-006870-f5w6fw6q 5550 20 to to IN cord-006870-f5w6fw6q 5550 21 the the DT cord-006870-f5w6fw6q 5550 22 ER ER NNP cord-006870-f5w6fw6q 5550 23 with with IN cord-006870-f5w6fw6q 5550 24 acute acute JJ cord-006870-f5w6fw6q 5550 25 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5550 26 and and CC cord-006870-f5w6fw6q 5550 27 right right RB cord-006870-f5w6fw6q 5550 28 - - HYPH cord-006870-f5w6fw6q 5550 29 sided sided JJ cord-006870-f5w6fw6q 5550 30 weakness weakness NN cord-006870-f5w6fw6q 5550 31 . . . cord-006870-f5w6fw6q 5551 1 Head Head NNP cord-006870-f5w6fw6q 5551 2 CT CT NNP cord-006870-f5w6fw6q 5551 3 - - HYPH cord-006870-f5w6fw6q 5551 4 scan scan NNP cord-006870-f5w6fw6q 5551 5 ( ( -LRB- cord-006870-f5w6fw6q 5551 6 HCT HCT NNP cord-006870-f5w6fw6q 5551 7 ) ) -RRB- cord-006870-f5w6fw6q 5551 8 revealed reveal VBD cord-006870-f5w6fw6q 5551 9 isolated isolate VBN cord-006870-f5w6fw6q 5551 10 IVH IVH NNP cord-006870-f5w6fw6q 5551 11 . . . cord-006870-f5w6fw6q 5552 1 CTA CTA NNP cord-006870-f5w6fw6q 5552 2 was be VBD cord-006870-f5w6fw6q 5552 3 notable notable JJ cord-006870-f5w6fw6q 5552 4 for for IN cord-006870-f5w6fw6q 5552 5 a a DT cord-006870-f5w6fw6q 5552 6 spot spot NN cord-006870-f5w6fw6q 5552 7 sign sign NN cord-006870-f5w6fw6q 5552 8 . . . cord-006870-f5w6fw6q 5553 1 It -PRON- PRP cord-006870-f5w6fw6q 5553 2 measures measure VBZ cord-006870-f5w6fw6q 5553 3 2.8 2.8 CD cord-006870-f5w6fw6q 5553 4 mm mm NNS cord-006870-f5w6fw6q 5553 5 in in IN cord-006870-f5w6fw6q 5553 6 diameter diameter NN cord-006870-f5w6fw6q 5553 7 and and CC cord-006870-f5w6fw6q 5553 8 175 175 CD cord-006870-f5w6fw6q 5553 9 HU HU NNP cord-006870-f5w6fw6q 5553 10 in in IN cord-006870-f5w6fw6q 5553 11 density density NN cord-006870-f5w6fw6q 5553 12 ( ( -LRB- cord-006870-f5w6fw6q 5553 13 surrounding surround VBG cord-006870-f5w6fw6q 5553 14 hematoma hematoma NN cord-006870-f5w6fw6q 5553 15 measures measure NNS cord-006870-f5w6fw6q 5553 16 80 80 CD cord-006870-f5w6fw6q 5553 17 HU HU NNP cord-006870-f5w6fw6q 5553 18 ) ) -RRB- cord-006870-f5w6fw6q 5553 19 . . . cord-006870-f5w6fw6q 5554 1 It -PRON- PRP cord-006870-f5w6fw6q 5554 2 lies lie VBZ cord-006870-f5w6fw6q 5554 3 within within IN cord-006870-f5w6fw6q 5554 4 the the DT cord-006870-f5w6fw6q 5554 5 hematoma hematoma NN cord-006870-f5w6fw6q 5554 6 without without IN cord-006870-f5w6fw6q 5554 7 connections connection NNS cord-006870-f5w6fw6q 5554 8 to to IN cord-006870-f5w6fw6q 5554 9 any any DT cord-006870-f5w6fw6q 5554 10 adjacent adjacent JJ cord-006870-f5w6fw6q 5554 11 vessel vessel NN cord-006870-f5w6fw6q 5554 12 . . . cord-006870-f5w6fw6q 5555 1 A a DT cord-006870-f5w6fw6q 5555 2 follow follow VB cord-006870-f5w6fw6q 5555 3 - - HYPH cord-006870-f5w6fw6q 5555 4 up up NN cord-006870-f5w6fw6q 5555 5 HCT hct NN cord-006870-f5w6fw6q 5555 6 after after IN cord-006870-f5w6fw6q 5555 7 four four CD cord-006870-f5w6fw6q 5555 8 hours hour NNS cord-006870-f5w6fw6q 5555 9 showed show VBD cord-006870-f5w6fw6q 5555 10 expansion expansion NN cord-006870-f5w6fw6q 5555 11 of of IN cord-006870-f5w6fw6q 5555 12 the the DT cord-006870-f5w6fw6q 5555 13 IVH IVH NNP cord-006870-f5w6fw6q 5555 14 . . . cord-006870-f5w6fw6q 5556 1 Although although IN cord-006870-f5w6fw6q 5556 2 seems seem VBZ cord-006870-f5w6fw6q 5556 3 uncommon uncommon JJ cord-006870-f5w6fw6q 5556 4 , , , cord-006870-f5w6fw6q 5556 5 looking look VBG cord-006870-f5w6fw6q 5556 6 for for IN cord-006870-f5w6fw6q 5556 7 a a DT cord-006870-f5w6fw6q 5556 8 spot spot NN cord-006870-f5w6fw6q 5556 9 sign sign NN cord-006870-f5w6fw6q 5556 10 in in IN cord-006870-f5w6fw6q 5556 11 isolated isolate VBN cord-006870-f5w6fw6q 5556 12 IVH IVH NNP cord-006870-f5w6fw6q 5556 13 can can MD cord-006870-f5w6fw6q 5556 14 also also RB cord-006870-f5w6fw6q 5556 15 anticipate anticipate VB cord-006870-f5w6fw6q 5556 16 expansion expansion NN cord-006870-f5w6fw6q 5556 17 of of IN cord-006870-f5w6fw6q 5556 18 the the DT cord-006870-f5w6fw6q 5556 19 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5556 20 . . . cord-006870-f5w6fw6q 5557 1 A a DT cord-006870-f5w6fw6q 5557 2 further further JJ cord-006870-f5w6fw6q 5557 3 study study NN cord-006870-f5w6fw6q 5557 4 is be VBZ cord-006870-f5w6fw6q 5557 5 needed need VBN cord-006870-f5w6fw6q 5557 6 to to TO cord-006870-f5w6fw6q 5557 7 validate validate VB cord-006870-f5w6fw6q 5557 8 this this DT cord-006870-f5w6fw6q 5557 9 observation observation NN cord-006870-f5w6fw6q 5557 10 and and CC cord-006870-f5w6fw6q 5557 11 calculate calculate VB cord-006870-f5w6fw6q 5557 12 the the DT cord-006870-f5w6fw6q 5557 13 prevalence prevalence NN cord-006870-f5w6fw6q 5557 14 of of IN cord-006870-f5w6fw6q 5557 15 the the DT cord-006870-f5w6fw6q 5557 16 spot spot NN cord-006870-f5w6fw6q 5557 17 sign sign NN cord-006870-f5w6fw6q 5557 18 in in IN cord-006870-f5w6fw6q 5557 19 isolated isolate VBN cord-006870-f5w6fw6q 5557 20 IVH IVH NNP cord-006870-f5w6fw6q 5557 21 . . . cord-006870-f5w6fw6q 5558 1 West West NNP cord-006870-f5w6fw6q 5558 2 Nile Nile NNP cord-006870-f5w6fw6q 5558 3 neuroinvasive neuroinvasive JJ cord-006870-f5w6fw6q 5558 4 disease disease NN cord-006870-f5w6fw6q 5558 5 may may MD cord-006870-f5w6fw6q 5558 6 present present VB cord-006870-f5w6fw6q 5558 7 with with IN cord-006870-f5w6fw6q 5558 8 nonspecific nonspecific JJ cord-006870-f5w6fw6q 5558 9 physical physical JJ cord-006870-f5w6fw6q 5558 10 exam exam NN cord-006870-f5w6fw6q 5558 11 and and CC cord-006870-f5w6fw6q 5558 12 imaging imaging NN cord-006870-f5w6fw6q 5558 13 findings finding NNS cord-006870-f5w6fw6q 5558 14 . . . cord-006870-f5w6fw6q 5559 1 To to IN cord-006870-f5w6fw6q 5559 2 our -PRON- PRP$ cord-006870-f5w6fw6q 5559 3 knowledge knowledge NN cord-006870-f5w6fw6q 5559 4 , , , cord-006870-f5w6fw6q 5559 5 this this DT cord-006870-f5w6fw6q 5559 6 is be VBZ cord-006870-f5w6fw6q 5559 7 the the DT cord-006870-f5w6fw6q 5559 8 first first JJ cord-006870-f5w6fw6q 5559 9 report report NN cord-006870-f5w6fw6q 5559 10 of of IN cord-006870-f5w6fw6q 5559 11 WNND WNND NNP cord-006870-f5w6fw6q 5559 12 involving involve VBG cord-006870-f5w6fw6q 5559 13 the the DT cord-006870-f5w6fw6q 5559 14 temporal temporal JJ cord-006870-f5w6fw6q 5559 15 lobe lobe NN cord-006870-f5w6fw6q 5559 16 in in IN cord-006870-f5w6fw6q 5559 17 adults adult NNS cord-006870-f5w6fw6q 5559 18 with with IN cord-006870-f5w6fw6q 5559 19 neuroimaging neuroimage VBG cord-006870-f5w6fw6q 5559 20 suggestive suggestive JJ cord-006870-f5w6fw6q 5559 21 of of IN cord-006870-f5w6fw6q 5559 22 limbic limbic NNP cord-006870-f5w6fw6q 5559 23 encephalitis encephalitis RB cord-006870-f5w6fw6q 5559 24 . . . cord-006870-f5w6fw6q 5560 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5560 2 patient patient NN cord-006870-f5w6fw6q 5560 3 presented present VBN cord-006870-f5w6fw6q 5560 4 in in IN cord-006870-f5w6fw6q 5560 5 winter winter NN cord-006870-f5w6fw6q 5560 6 and and CC cord-006870-f5w6fw6q 5560 7 developed develop VBD cord-006870-f5w6fw6q 5560 8 autonomic autonomic JJ cord-006870-f5w6fw6q 5560 9 instability instability NN cord-006870-f5w6fw6q 5560 10 and and CC cord-006870-f5w6fw6q 5560 11 sensory sensory JJ cord-006870-f5w6fw6q 5560 12 deficits deficit NNS cord-006870-f5w6fw6q 5560 13 , , , cord-006870-f5w6fw6q 5560 14 which which WDT cord-006870-f5w6fw6q 5560 15 are be VBP cord-006870-f5w6fw6q 5560 16 all all DT cord-006870-f5w6fw6q 5560 17 rare rare JJ cord-006870-f5w6fw6q 5560 18 findings finding NNS cord-006870-f5w6fw6q 5560 19 in in IN cord-006870-f5w6fw6q 5560 20 WNND WNND NNP cord-006870-f5w6fw6q 5560 21 . . . cord-006870-f5w6fw6q 5561 1 73-year 73-year JJ cord-006870-f5w6fw6q 5561 2 - - HYPH cord-006870-f5w6fw6q 5561 3 old old JJ cord-006870-f5w6fw6q 5561 4 Texan Texan NNP cord-006870-f5w6fw6q 5561 5 with with IN cord-006870-f5w6fw6q 5561 6 DM DM NNP cord-006870-f5w6fw6q 5561 7 presented present VBN cord-006870-f5w6fw6q 5561 8 with with IN cord-006870-f5w6fw6q 5561 9 acute acute JJ cord-006870-f5w6fw6q 5561 10 confusion confusion NN cord-006870-f5w6fw6q 5561 11 and and CC cord-006870-f5w6fw6q 5561 12 seizure seizure NN cord-006870-f5w6fw6q 5561 13 in in IN cord-006870-f5w6fw6q 5561 14 November November NNP cord-006870-f5w6fw6q 5561 15 . . . cord-006870-f5w6fw6q 5562 1 Patient Patient NNP cord-006870-f5w6fw6q 5562 2 complained complain VBD cord-006870-f5w6fw6q 5562 3 of of IN cord-006870-f5w6fw6q 5562 4 headache headache NN cord-006870-f5w6fw6q 5562 5 , , , cord-006870-f5w6fw6q 5562 6 fever fever NN cord-006870-f5w6fw6q 5562 7 , , , cord-006870-f5w6fw6q 5562 8 diarrhea diarrhea NN cord-006870-f5w6fw6q 5562 9 and and CC cord-006870-f5w6fw6q 5562 10 lower low JJR cord-006870-f5w6fw6q 5562 11 extremity extremity NN cord-006870-f5w6fw6q 5562 12 weakness weakness NN cord-006870-f5w6fw6q 5562 13 after after IN cord-006870-f5w6fw6q 5562 14 a a DT cord-006870-f5w6fw6q 5562 15 fishing fishing NN cord-006870-f5w6fw6q 5562 16 trip trip NN cord-006870-f5w6fw6q 5562 17 . . . cord-006870-f5w6fw6q 5563 1 Patient Patient NNP cord-006870-f5w6fw6q 5563 2 was be VBD cord-006870-f5w6fw6q 5563 3 febrile febrile JJ cord-006870-f5w6fw6q 5563 4 with with IN cord-006870-f5w6fw6q 5563 5 mosquito mosquito NN cord-006870-f5w6fw6q 5563 6 bites bite NNS cord-006870-f5w6fw6q 5563 7 on on IN cord-006870-f5w6fw6q 5563 8 his -PRON- PRP$ cord-006870-f5w6fw6q 5563 9 arms arm NNS cord-006870-f5w6fw6q 5563 10 . . . cord-006870-f5w6fw6q 5564 1 Neurological neurological JJ cord-006870-f5w6fw6q 5564 2 exam exam NN cord-006870-f5w6fw6q 5564 3 was be VBD cord-006870-f5w6fw6q 5564 4 significant significant JJ cord-006870-f5w6fw6q 5564 5 for for IN cord-006870-f5w6fw6q 5564 6 comatose comatose JJ cord-006870-f5w6fw6q 5564 7 state state NN cord-006870-f5w6fw6q 5564 8 , , , cord-006870-f5w6fw6q 5564 9 absent absent JJ cord-006870-f5w6fw6q 5564 10 brainstem brainstem NN cord-006870-f5w6fw6q 5564 11 and and CC cord-006870-f5w6fw6q 5564 12 deep deep JJ cord-006870-f5w6fw6q 5564 13 tendon tendon NN cord-006870-f5w6fw6q 5564 14 reflexes reflex NNS cord-006870-f5w6fw6q 5564 15 , , , cord-006870-f5w6fw6q 5564 16 and and CC cord-006870-f5w6fw6q 5564 17 flaccid flaccid JJ cord-006870-f5w6fw6q 5564 18 paraparesis paraparesis NN cord-006870-f5w6fw6q 5564 19 . . . cord-006870-f5w6fw6q 5565 1 He -PRON- PRP cord-006870-f5w6fw6q 5565 2 developed develop VBD cord-006870-f5w6fw6q 5565 3 autonomic autonomic JJ cord-006870-f5w6fw6q 5565 4 instability instability NN cord-006870-f5w6fw6q 5565 5 with with IN cord-006870-f5w6fw6q 5565 6 labile labile JJ cord-006870-f5w6fw6q 5565 7 blood blood NN cord-006870-f5w6fw6q 5565 8 pressures pressure NNS cord-006870-f5w6fw6q 5565 9 . . . cord-006870-f5w6fw6q 5566 1 LP LP NNP cord-006870-f5w6fw6q 5566 2 revealed reveal VBD cord-006870-f5w6fw6q 5566 3 13 13 CD cord-006870-f5w6fw6q 5566 4 WBC WBC NNP cord-006870-f5w6fw6q 5566 5 / / SYM cord-006870-f5w6fw6q 5566 6 mm3 mm3 NNS cord-006870-f5w6fw6q 5566 7 ( ( -LRB- cord-006870-f5w6fw6q 5566 8 monocyte monocyte NNP cord-006870-f5w6fw6q 5566 9 predominance predominance NN cord-006870-f5w6fw6q 5566 10 ) ) -RRB- cord-006870-f5w6fw6q 5566 11 , , , cord-006870-f5w6fw6q 5566 12 23 23 CD cord-006870-f5w6fw6q 5566 13 RBC RBC NNP cord-006870-f5w6fw6q 5566 14 / / SYM cord-006870-f5w6fw6q 5566 15 mm3 mm3 NNS cord-006870-f5w6fw6q 5566 16 , , , cord-006870-f5w6fw6q 5566 17 glucose glucose VBG cord-006870-f5w6fw6q 5566 18 99 99 CD cord-006870-f5w6fw6q 5566 19 mg mg NNP cord-006870-f5w6fw6q 5566 20 / / SYM cord-006870-f5w6fw6q 5566 21 dL dl NN cord-006870-f5w6fw6q 5566 22 , , , cord-006870-f5w6fw6q 5566 23 elevated elevated JJ cord-006870-f5w6fw6q 5566 24 protein protein NN cord-006870-f5w6fw6q 5566 25 of of IN cord-006870-f5w6fw6q 5566 26 82 82 CD cord-006870-f5w6fw6q 5566 27 mg mg NNP cord-006870-f5w6fw6q 5566 28 / / SYM cord-006870-f5w6fw6q 5566 29 dL dl NN cord-006870-f5w6fw6q 5566 30 , , , cord-006870-f5w6fw6q 5566 31 and and CC cord-006870-f5w6fw6q 5566 32 a a DT cord-006870-f5w6fw6q 5566 33 positive positive JJ cord-006870-f5w6fw6q 5566 34 West West NNP cord-006870-f5w6fw6q 5566 35 Nile Nile NNP cord-006870-f5w6fw6q 5566 36 virus virus NN cord-006870-f5w6fw6q 5566 37 ( ( -LRB- cord-006870-f5w6fw6q 5566 38 WNV WNV NNP cord-006870-f5w6fw6q 5566 39 ) ) -RRB- cord-006870-f5w6fw6q 5566 40 IgM IgM NNP cord-006870-f5w6fw6q 5566 41 antibody antibody NN cord-006870-f5w6fw6q 5566 42 ; ; : cord-006870-f5w6fw6q 5566 43 gram gram NN cord-006870-f5w6fw6q 5566 44 stain stain NN cord-006870-f5w6fw6q 5566 45 , , , cord-006870-f5w6fw6q 5566 46 HCV HCV NNP cord-006870-f5w6fw6q 5566 47 PCR PCR NNP cord-006870-f5w6fw6q 5566 48 , , , cord-006870-f5w6fw6q 5566 49 and and CC cord-006870-f5w6fw6q 5566 50 the the DT cord-006870-f5w6fw6q 5566 51 paraneoplastic paraneoplastic JJ cord-006870-f5w6fw6q 5566 52 and and CC cord-006870-f5w6fw6q 5566 53 autoimmune autoimmune JJ cord-006870-f5w6fw6q 5566 54 panels panel NNS cord-006870-f5w6fw6q 5566 55 were be VBD cord-006870-f5w6fw6q 5566 56 negative negative JJ cord-006870-f5w6fw6q 5566 57 . . . cord-006870-f5w6fw6q 5567 1 EEG EEG NNP cord-006870-f5w6fw6q 5567 2 showed show VBD cord-006870-f5w6fw6q 5567 3 severe severe JJ cord-006870-f5w6fw6q 5567 4 diffuse diffuse JJ cord-006870-f5w6fw6q 5567 5 brain brain NN cord-006870-f5w6fw6q 5567 6 slowing slow VBG cord-006870-f5w6fw6q 5567 7 . . . cord-006870-f5w6fw6q 5568 1 MRI MRI NNP cord-006870-f5w6fw6q 5568 2 brain brain NN cord-006870-f5w6fw6q 5568 3 had have VBD cord-006870-f5w6fw6q 5568 4 T2 T2 NNP cord-006870-f5w6fw6q 5568 5 Flair Flair NNP cord-006870-f5w6fw6q 5568 6 and and CC cord-006870-f5w6fw6q 5568 7 DWI DWI NNP cord-006870-f5w6fw6q 5568 8 changes change NNS cord-006870-f5w6fw6q 5568 9 in in IN cord-006870-f5w6fw6q 5568 10 right right JJ cord-006870-f5w6fw6q 5568 11 hippocampus hippocampus NN cord-006870-f5w6fw6q 5568 12 and and CC cord-006870-f5w6fw6q 5568 13 posterior posterior JJ cord-006870-f5w6fw6q 5568 14 limb limb NN cord-006870-f5w6fw6q 5568 15 of of IN cord-006870-f5w6fw6q 5568 16 internal internal JJ cord-006870-f5w6fw6q 5568 17 capsule capsule NN cord-006870-f5w6fw6q 5568 18 . . . cord-006870-f5w6fw6q 5569 1 EMG EMG NNP cord-006870-f5w6fw6q 5569 2 described describe VBD cord-006870-f5w6fw6q 5569 3 severe severe JJ cord-006870-f5w6fw6q 5569 4 subacute subacute JJ cord-006870-f5w6fw6q 5569 5 sensorimotor sensorimotor JJ cord-006870-f5w6fw6q 5569 6 axonal axonal JJ cord-006870-f5w6fw6q 5569 7 polyneuropathy polyneuropathy NNS cord-006870-f5w6fw6q 5569 8 without without IN cord-006870-f5w6fw6q 5569 9 prolonged prolong VBN cord-006870-f5w6fw6q 5569 10 distal distal JJ cord-006870-f5w6fw6q 5569 11 latencies latency NNS cord-006870-f5w6fw6q 5569 12 and and CC cord-006870-f5w6fw6q 5569 13 normal normal JJ cord-006870-f5w6fw6q 5569 14 conduction conduction NN cord-006870-f5w6fw6q 5569 15 velocities velocity NNS cord-006870-f5w6fw6q 5569 16 . . . cord-006870-f5w6fw6q 5570 1 He -PRON- PRP cord-006870-f5w6fw6q 5570 2 received receive VBD cord-006870-f5w6fw6q 5570 3 5 5 CD cord-006870-f5w6fw6q 5570 4 days day NNS cord-006870-f5w6fw6q 5570 5 of of IN cord-006870-f5w6fw6q 5570 6 IVIG IVIG NNP cord-006870-f5w6fw6q 5570 7 without without IN cord-006870-f5w6fw6q 5570 8 improvement improvement NN cord-006870-f5w6fw6q 5570 9 and and CC cord-006870-f5w6fw6q 5570 10 was be VBD cord-006870-f5w6fw6q 5570 11 terminally terminally RB cord-006870-f5w6fw6q 5570 12 extubated extubate VBN cord-006870-f5w6fw6q 5570 13 . . . cord-006870-f5w6fw6q 5571 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5571 2 patient patient NN cord-006870-f5w6fw6q 5571 3 presented present VBD cord-006870-f5w6fw6q 5571 4 with with IN cord-006870-f5w6fw6q 5571 5 both both DT cord-006870-f5w6fw6q 5571 6 clinical clinical JJ cord-006870-f5w6fw6q 5571 7 entities entity NNS cord-006870-f5w6fw6q 5571 8 of of IN cord-006870-f5w6fw6q 5571 9 West West NNP cord-006870-f5w6fw6q 5571 10 Nile Nile NNP cord-006870-f5w6fw6q 5571 11 : : : cord-006870-f5w6fw6q 5571 12 WN WN NNP cord-006870-f5w6fw6q 5571 13 fever fever NN cord-006870-f5w6fw6q 5571 14 and and CC cord-006870-f5w6fw6q 5571 15 WNND WNND NNP cord-006870-f5w6fw6q 5571 16 ( ( -LRB- cord-006870-f5w6fw6q 5571 17 present present JJ cord-006870-f5w6fw6q 5571 18 in in IN cord-006870-f5w6fw6q 5571 19 less less JJR cord-006870-f5w6fw6q 5571 20 than than IN cord-006870-f5w6fw6q 5571 21 1 1 CD cord-006870-f5w6fw6q 5571 22 % % NN cord-006870-f5w6fw6q 5571 23 of of IN cord-006870-f5w6fw6q 5571 24 cases case NNS cord-006870-f5w6fw6q 5571 25 ) ) -RRB- cord-006870-f5w6fw6q 5571 26 . . . cord-006870-f5w6fw6q 5572 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5572 2 patient patient NN cord-006870-f5w6fw6q 5572 3 had have VBD cord-006870-f5w6fw6q 5572 4 axonal axonal JJ cord-006870-f5w6fw6q 5572 5 polyneuropathy polyneuropathy NNS cord-006870-f5w6fw6q 5572 6 with with IN cord-006870-f5w6fw6q 5572 7 paralysis paralysis NN cord-006870-f5w6fw6q 5572 8 which which WDT cord-006870-f5w6fw6q 5572 9 is be VBZ cord-006870-f5w6fw6q 5572 10 due due JJ cord-006870-f5w6fw6q 5572 11 to to IN cord-006870-f5w6fw6q 5572 12 inflammatory inflammatory JJ cord-006870-f5w6fw6q 5572 13 changes change NNS cord-006870-f5w6fw6q 5572 14 in in IN cord-006870-f5w6fw6q 5572 15 the the DT cord-006870-f5w6fw6q 5572 16 white white JJ cord-006870-f5w6fw6q 5572 17 matter matter NN cord-006870-f5w6fw6q 5572 18 tracts tract NNS cord-006870-f5w6fw6q 5572 19 affecting affect VBG cord-006870-f5w6fw6q 5572 20 spinal spinal JJ cord-006870-f5w6fw6q 5572 21 sensory sensory JJ cord-006870-f5w6fw6q 5572 22 pathways pathway NNS cord-006870-f5w6fw6q 5572 23 . . . cord-006870-f5w6fw6q 5573 1 Sympathetic sympathetic JJ cord-006870-f5w6fw6q 5573 2 ganglia ganglion NNS cord-006870-f5w6fw6q 5573 3 involvement involvement NN cord-006870-f5w6fw6q 5573 4 caused cause VBD cord-006870-f5w6fw6q 5573 5 the the DT cord-006870-f5w6fw6q 5573 6 autonomic autonomic JJ cord-006870-f5w6fw6q 5573 7 instability instability NN cord-006870-f5w6fw6q 5573 8 , , , cord-006870-f5w6fw6q 5573 9 another another DT cord-006870-f5w6fw6q 5573 10 very very RB cord-006870-f5w6fw6q 5573 11 rare rare JJ cord-006870-f5w6fw6q 5573 12 manifestation manifestation NN cord-006870-f5w6fw6q 5573 13 of of IN cord-006870-f5w6fw6q 5573 14 WNND WNND NNP cord-006870-f5w6fw6q 5573 15 . . . cord-006870-f5w6fw6q 5574 1 November November NNP cord-006870-f5w6fw6q 5574 2 presentation presentation NN cord-006870-f5w6fw6q 5574 3 was be VBD cord-006870-f5w6fw6q 5574 4 due due JJ cord-006870-f5w6fw6q 5574 5 to to IN cord-006870-f5w6fw6q 5574 6 warmer warm JJR cord-006870-f5w6fw6q 5574 7 Texas Texas NNP cord-006870-f5w6fw6q 5574 8 winter winter NN cord-006870-f5w6fw6q 5574 9 . . . cord-006870-f5w6fw6q 5575 1 Recognize recognize VB cord-006870-f5w6fw6q 5575 2 that that IN cord-006870-f5w6fw6q 5575 3 West West NNP cord-006870-f5w6fw6q 5575 4 Nile Nile NNP cord-006870-f5w6fw6q 5575 5 fever fever NN cord-006870-f5w6fw6q 5575 6 and and CC cord-006870-f5w6fw6q 5575 7 West West NNP cord-006870-f5w6fw6q 5575 8 Nile Nile NNP cord-006870-f5w6fw6q 5575 9 neuroinvasive neuroinvasive JJ cord-006870-f5w6fw6q 5575 10 disease disease NN cord-006870-f5w6fw6q 5575 11 may may MD cord-006870-f5w6fw6q 5575 12 present present VB cord-006870-f5w6fw6q 5575 13 together together RB cord-006870-f5w6fw6q 5575 14 in in IN cord-006870-f5w6fw6q 5575 15 winter winter NN cord-006870-f5w6fw6q 5575 16 . . . cord-006870-f5w6fw6q 5576 1 Recognize recognize VB cord-006870-f5w6fw6q 5576 2 that that IN cord-006870-f5w6fw6q 5576 3 West West NNP cord-006870-f5w6fw6q 5576 4 Nile Nile NNP cord-006870-f5w6fw6q 5576 5 neuroinvasive neuroinvasive JJ cord-006870-f5w6fw6q 5576 6 disease disease NN cord-006870-f5w6fw6q 5576 7 can can MD cord-006870-f5w6fw6q 5576 8 present present VB cord-006870-f5w6fw6q 5576 9 with with IN cord-006870-f5w6fw6q 5576 10 rare rare JJ cord-006870-f5w6fw6q 5576 11 temporal temporal JJ cord-006870-f5w6fw6q 5576 12 lobe lobe NN cord-006870-f5w6fw6q 5576 13 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 5576 14 , , , cord-006870-f5w6fw6q 5576 15 sensory sensory JJ cord-006870-f5w6fw6q 5576 16 involvement involvement NN cord-006870-f5w6fw6q 5576 17 , , , cord-006870-f5w6fw6q 5576 18 and and CC cord-006870-f5w6fw6q 5576 19 autonomic autonomic JJ cord-006870-f5w6fw6q 5576 20 instability instability NN cord-006870-f5w6fw6q 5576 21 . . . cord-006870-f5w6fw6q 5577 1 Intracerebral Intracerebral NNP cord-006870-f5w6fw6q 5577 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5577 3 ( ( -LRB- cord-006870-f5w6fw6q 5577 4 ICH ICH NNP cord-006870-f5w6fw6q 5577 5 ) ) -RRB- cord-006870-f5w6fw6q 5577 6 is be VBZ cord-006870-f5w6fw6q 5577 7 a a DT cord-006870-f5w6fw6q 5577 8 common common JJ cord-006870-f5w6fw6q 5577 9 pathology pathology NN cord-006870-f5w6fw6q 5577 10 seen see VBN cord-006870-f5w6fw6q 5577 11 in in IN cord-006870-f5w6fw6q 5577 12 the the DT cord-006870-f5w6fw6q 5577 13 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 5577 14 care care NN cord-006870-f5w6fw6q 5577 15 setting set VBG cord-006870-f5w6fw6q 5577 16 that that WDT cord-006870-f5w6fw6q 5577 17 can can MD cord-006870-f5w6fw6q 5577 18 be be VB cord-006870-f5w6fw6q 5577 19 associated associate VBN cord-006870-f5w6fw6q 5577 20 with with IN cord-006870-f5w6fw6q 5577 21 significant significant JJ cord-006870-f5w6fw6q 5577 22 morbidity morbidity NN cord-006870-f5w6fw6q 5577 23 and and CC cord-006870-f5w6fw6q 5577 24 mortality mortality NN cord-006870-f5w6fw6q 5577 25 . . . cord-006870-f5w6fw6q 5578 1 The the DT cord-006870-f5w6fw6q 5578 2 use use NN cord-006870-f5w6fw6q 5578 3 of of IN cord-006870-f5w6fw6q 5578 4 sympathomimetic sympathomimetic JJ cord-006870-f5w6fw6q 5578 5 agents agent NNS cord-006870-f5w6fw6q 5578 6 containing contain VBG cord-006870-f5w6fw6q 5578 7 phenylpropanolamine phenylpropanolamine NNP cord-006870-f5w6fw6q 5578 8 ( ( -LRB- cord-006870-f5w6fw6q 5578 9 PPA PPA NNP cord-006870-f5w6fw6q 5578 10 ) ) -RRB- cord-006870-f5w6fw6q 5578 11 have have VBP cord-006870-f5w6fw6q 5578 12 been be VBN cord-006870-f5w6fw6q 5578 13 associated associate VBN cord-006870-f5w6fw6q 5578 14 with with IN cord-006870-f5w6fw6q 5578 15 ICH ICH NNP cord-006870-f5w6fw6q 5578 16 in in IN cord-006870-f5w6fw6q 5578 17 the the DT cord-006870-f5w6fw6q 5578 18 past past NN cord-006870-f5w6fw6q 5578 19 which which WDT cord-006870-f5w6fw6q 5578 20 lead lead VBP cord-006870-f5w6fw6q 5578 21 to to IN cord-006870-f5w6fw6q 5578 22 the the DT cord-006870-f5w6fw6q 5578 23 drugs drug NNS cord-006870-f5w6fw6q 5578 24 ' ' POS cord-006870-f5w6fw6q 5578 25 removal removal NN cord-006870-f5w6fw6q 5578 26 by by IN cord-006870-f5w6fw6q 5578 27 the the DT cord-006870-f5w6fw6q 5578 28 FDA FDA NNP cord-006870-f5w6fw6q 5578 29 as as IN cord-006870-f5w6fw6q 5578 30 an an DT cord-006870-f5w6fw6q 5578 31 over over IN cord-006870-f5w6fw6q 5578 32 the the DT cord-006870-f5w6fw6q 5578 33 counter counter JJ cord-006870-f5w6fw6q 5578 34 medication medication NN cord-006870-f5w6fw6q 5578 35 in in IN cord-006870-f5w6fw6q 5578 36 2005 2005 CD cord-006870-f5w6fw6q 5578 37 . . . cord-006870-f5w6fw6q 5579 1 We -PRON- PRP cord-006870-f5w6fw6q 5579 2 report report VBP cord-006870-f5w6fw6q 5579 3 a a DT cord-006870-f5w6fw6q 5579 4 case case NN cord-006870-f5w6fw6q 5579 5 in in IN cord-006870-f5w6fw6q 5579 6 which which WDT cord-006870-f5w6fw6q 5579 7 PPA PPA NNP cord-006870-f5w6fw6q 5579 8 was be VBD cord-006870-f5w6fw6q 5579 9 the the DT cord-006870-f5w6fw6q 5579 10 etiology etiology NN cord-006870-f5w6fw6q 5579 11 for for IN cord-006870-f5w6fw6q 5579 12 a a DT cord-006870-f5w6fw6q 5579 13 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5579 14 ICH ich NN cord-006870-f5w6fw6q 5579 15 in in IN cord-006870-f5w6fw6q 5579 16 a a DT cord-006870-f5w6fw6q 5579 17 patient patient NN cord-006870-f5w6fw6q 5579 18 who who WP cord-006870-f5w6fw6q 5579 19 was be VBD cord-006870-f5w6fw6q 5579 20 taking take VBG cord-006870-f5w6fw6q 5579 21 an an DT cord-006870-f5w6fw6q 5579 22 appetite appetite NN cord-006870-f5w6fw6q 5579 23 suppressant suppressant NN cord-006870-f5w6fw6q 5579 24 . . . cord-006870-f5w6fw6q 5580 1 Case case NN cord-006870-f5w6fw6q 5580 2 report report NN cord-006870-f5w6fw6q 5580 3 and and CC cord-006870-f5w6fw6q 5580 4 review review NN cord-006870-f5w6fw6q 5580 5 of of IN cord-006870-f5w6fw6q 5580 6 the the DT cord-006870-f5w6fw6q 5580 7 literature literature NN cord-006870-f5w6fw6q 5581 1 We -PRON- PRP cord-006870-f5w6fw6q 5581 2 report report VBP cord-006870-f5w6fw6q 5581 3 a a DT cord-006870-f5w6fw6q 5581 4 case case NN cord-006870-f5w6fw6q 5581 5 of of IN cord-006870-f5w6fw6q 5581 6 a a DT cord-006870-f5w6fw6q 5581 7 40 40 CD cord-006870-f5w6fw6q 5581 8 year year NN cord-006870-f5w6fw6q 5581 9 old old JJ cord-006870-f5w6fw6q 5581 10 female female NN cord-006870-f5w6fw6q 5581 11 with with IN cord-006870-f5w6fw6q 5581 12 no no DT cord-006870-f5w6fw6q 5581 13 prior prior JJ cord-006870-f5w6fw6q 5581 14 medical medical JJ cord-006870-f5w6fw6q 5581 15 history history NN cord-006870-f5w6fw6q 5581 16 , , , cord-006870-f5w6fw6q 5581 17 who who WP cord-006870-f5w6fw6q 5581 18 presented present VBD cord-006870-f5w6fw6q 5581 19 with with IN cord-006870-f5w6fw6q 5581 20 sudden sudden JJ cord-006870-f5w6fw6q 5581 21 onset onset NN cord-006870-f5w6fw6q 5581 22 left leave VBD cord-006870-f5w6fw6q 5581 23 sided sided JJ cord-006870-f5w6fw6q 5581 24 hemiparesis hemiparesis NNP cord-006870-f5w6fw6q 5581 25 and and CC cord-006870-f5w6fw6q 5581 26 hemianesthesia hemianesthesia NNP cord-006870-f5w6fw6q 5581 27 found find VBD cord-006870-f5w6fw6q 5581 28 to to TO cord-006870-f5w6fw6q 5581 29 be be VB cord-006870-f5w6fw6q 5581 30 due due JJ cord-006870-f5w6fw6q 5581 31 to to IN cord-006870-f5w6fw6q 5581 32 a a DT cord-006870-f5w6fw6q 5581 33 right right JJ cord-006870-f5w6fw6q 5581 34 striatocapsular striatocapsular NNP cord-006870-f5w6fw6q 5581 35 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 5581 36 hematoma hematoma NN cord-006870-f5w6fw6q 5581 37 . . . cord-006870-f5w6fw6q 5582 1 Systolic systolic JJ cord-006870-f5w6fw6q 5582 2 blood blood NN cord-006870-f5w6fw6q 5582 3 pressures pressure NNS cord-006870-f5w6fw6q 5582 4 at at IN cord-006870-f5w6fw6q 5582 5 presentation presentation NN cord-006870-f5w6fw6q 5582 6 and and CC cord-006870-f5w6fw6q 5582 7 throughout throughout IN cord-006870-f5w6fw6q 5582 8 the the DT cord-006870-f5w6fw6q 5582 9 hospital hospital NN cord-006870-f5w6fw6q 5582 10 course course NN cord-006870-f5w6fw6q 5582 11 were be VBD cord-006870-f5w6fw6q 5582 12 normal normal JJ cord-006870-f5w6fw6q 5582 13 . . . cord-006870-f5w6fw6q 5583 1 Extensive extensive JJ cord-006870-f5w6fw6q 5583 2 work work NN cord-006870-f5w6fw6q 5583 3 up up IN cord-006870-f5w6fw6q 5583 4 including include VBG cord-006870-f5w6fw6q 5583 5 multiple multiple JJ cord-006870-f5w6fw6q 5583 6 CT CT NNP cord-006870-f5w6fw6q 5583 7 scans scan NNS cord-006870-f5w6fw6q 5583 8 of of IN cord-006870-f5w6fw6q 5583 9 the the DT cord-006870-f5w6fw6q 5583 10 head head NN cord-006870-f5w6fw6q 5583 11 , , , cord-006870-f5w6fw6q 5583 12 MRI MRI NNP cord-006870-f5w6fw6q 5583 13 brain brain NN cord-006870-f5w6fw6q 5583 14 , , , cord-006870-f5w6fw6q 5583 15 CT CT NNP cord-006870-f5w6fw6q 5583 16 angiography angiography NN cord-006870-f5w6fw6q 5583 17 , , , cord-006870-f5w6fw6q 5583 18 MR MR NNP cord-006870-f5w6fw6q 5583 19 angiography angiography NNP cord-006870-f5w6fw6q 5583 20 and and CC cord-006870-f5w6fw6q 5583 21 Digital Digital NNP cord-006870-f5w6fw6q 5583 22 Subtraction Subtraction NNP cord-006870-f5w6fw6q 5583 23 Angiography Angiography NNP cord-006870-f5w6fw6q 5583 24 were be VBD cord-006870-f5w6fw6q 5583 25 performed perform VBN cord-006870-f5w6fw6q 5583 26 with with IN cord-006870-f5w6fw6q 5583 27 no no DT cord-006870-f5w6fw6q 5583 28 evidence evidence NN cord-006870-f5w6fw6q 5583 29 of of IN cord-006870-f5w6fw6q 5583 30 any any DT cord-006870-f5w6fw6q 5583 31 vessel vessel NN cord-006870-f5w6fw6q 5583 32 abnormality abnormality NN cord-006870-f5w6fw6q 5583 33 . . . cord-006870-f5w6fw6q 5584 1 Etiology etiology NN cord-006870-f5w6fw6q 5584 2 of of IN cord-006870-f5w6fw6q 5584 3 the the DT cord-006870-f5w6fw6q 5584 4 ICH ICH NNP cord-006870-f5w6fw6q 5584 5 was be VBD cord-006870-f5w6fw6q 5584 6 attributed attribute VBN cord-006870-f5w6fw6q 5584 7 to to IN cord-006870-f5w6fw6q 5584 8 the the DT cord-006870-f5w6fw6q 5584 9 use use NN cord-006870-f5w6fw6q 5584 10 of of IN cord-006870-f5w6fw6q 5584 11 PPA PPA NNP cord-006870-f5w6fw6q 5584 12 . . . cord-006870-f5w6fw6q 5585 1 In in IN cord-006870-f5w6fw6q 5585 2 young young JJ cord-006870-f5w6fw6q 5585 3 patients patient NNS cord-006870-f5w6fw6q 5585 4 with with IN cord-006870-f5w6fw6q 5585 5 no no DT cord-006870-f5w6fw6q 5585 6 known know VBN cord-006870-f5w6fw6q 5585 7 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 5585 8 , , , cord-006870-f5w6fw6q 5585 9 PPA PPA NNP cord-006870-f5w6fw6q 5585 10 use use NN cord-006870-f5w6fw6q 5585 11 should should MD cord-006870-f5w6fw6q 5585 12 be be VB cord-006870-f5w6fw6q 5585 13 considered consider VBN cord-006870-f5w6fw6q 5585 14 a a DT cord-006870-f5w6fw6q 5585 15 primary primary JJ cord-006870-f5w6fw6q 5585 16 etiology etiology NN cord-006870-f5w6fw6q 5585 17 of of IN cord-006870-f5w6fw6q 5585 18 ICH ICH NNP cord-006870-f5w6fw6q 5585 19 when when WRB cord-006870-f5w6fw6q 5585 20 no no DT cord-006870-f5w6fw6q 5585 21 intracranial intracranial JJ cord-006870-f5w6fw6q 5585 22 vessel vessel NN cord-006870-f5w6fw6q 5585 23 abnormality abnormality NN cord-006870-f5w6fw6q 5585 24 can can MD cord-006870-f5w6fw6q 5585 25 be be VB cord-006870-f5w6fw6q 5585 26 detected detect VBN cord-006870-f5w6fw6q 5585 27 . . . cord-006870-f5w6fw6q 5586 1 Seizures seizure NNS cord-006870-f5w6fw6q 5586 2 have have VBP cord-006870-f5w6fw6q 5586 3 been be VBN cord-006870-f5w6fw6q 5586 4 known know VBN cord-006870-f5w6fw6q 5586 5 to to TO cord-006870-f5w6fw6q 5586 6 cause cause VB cord-006870-f5w6fw6q 5586 7 sudden sudden JJ cord-006870-f5w6fw6q 5586 8 death death NN cord-006870-f5w6fw6q 5586 9 , , , cord-006870-f5w6fw6q 5586 10 but but CC cord-006870-f5w6fw6q 5586 11 reports report NNS cord-006870-f5w6fw6q 5586 12 in in IN cord-006870-f5w6fw6q 5586 13 the the DT cord-006870-f5w6fw6q 5586 14 literature literature NN cord-006870-f5w6fw6q 5586 15 of of IN cord-006870-f5w6fw6q 5586 16 only only JJ cord-006870-f5w6fw6q 5586 17 cardiopulmonary cardiopulmonary JJ cord-006870-f5w6fw6q 5586 18 failure failure NN cord-006870-f5w6fw6q 5586 19 in in IN cord-006870-f5w6fw6q 5586 20 cases case NNS cord-006870-f5w6fw6q 5586 21 of of IN cord-006870-f5w6fw6q 5586 22 sudden sudden JJ cord-006870-f5w6fw6q 5586 23 unexpected unexpected JJ cord-006870-f5w6fw6q 5586 24 death death NN cord-006870-f5w6fw6q 5586 25 in in IN cord-006870-f5w6fw6q 5586 26 epilepsy epilepsy NN cord-006870-f5w6fw6q 5586 27 ( ( -LRB- cord-006870-f5w6fw6q 5586 28 SUDEP SUDEP NNP cord-006870-f5w6fw6q 5586 29 ) ) -RRB- cord-006870-f5w6fw6q 5586 30 . . . cord-006870-f5w6fw6q 5587 1 We -PRON- PRP cord-006870-f5w6fw6q 5587 2 present present VBP cord-006870-f5w6fw6q 5587 3 the the DT cord-006870-f5w6fw6q 5587 4 case case NN cord-006870-f5w6fw6q 5587 5 of of IN cord-006870-f5w6fw6q 5587 6 a a DT cord-006870-f5w6fw6q 5587 7 patient patient NN cord-006870-f5w6fw6q 5587 8 who who WP cord-006870-f5w6fw6q 5587 9 presented present VBD cord-006870-f5w6fw6q 5587 10 post post JJ cord-006870-f5w6fw6q 5587 11 - - JJ cord-006870-f5w6fw6q 5587 12 seizure seizure JJ cord-006870-f5w6fw6q 5587 13 and and CC cord-006870-f5w6fw6q 5587 14 developed develop VBD cord-006870-f5w6fw6q 5587 15 sudden sudden JJ cord-006870-f5w6fw6q 5587 16 progressive progressive JJ cord-006870-f5w6fw6q 5587 17 and and CC cord-006870-f5w6fw6q 5587 18 fatal fatal JJ cord-006870-f5w6fw6q 5587 19 cerebral cerebral JJ cord-006870-f5w6fw6q 5587 20 edema edema NN cord-006870-f5w6fw6q 5587 21 within within IN cord-006870-f5w6fw6q 5587 22 14 14 CD cord-006870-f5w6fw6q 5587 23 hours hour NNS cord-006870-f5w6fw6q 5587 24 after after IN cord-006870-f5w6fw6q 5587 25 a a DT cord-006870-f5w6fw6q 5587 26 second second JJ cord-006870-f5w6fw6q 5587 27 seizure seizure NN cord-006870-f5w6fw6q 5587 28 . . . cord-006870-f5w6fw6q 5588 1 A a DT cord-006870-f5w6fw6q 5588 2 22 22 CD cord-006870-f5w6fw6q 5588 3 year year NN cord-006870-f5w6fw6q 5588 4 old old JJ cord-006870-f5w6fw6q 5588 5 female female NN cord-006870-f5w6fw6q 5588 6 with with IN cord-006870-f5w6fw6q 5588 7 a a DT cord-006870-f5w6fw6q 5588 8 history history NN cord-006870-f5w6fw6q 5588 9 of of IN cord-006870-f5w6fw6q 5588 10 Down Down NNP cord-006870-f5w6fw6q 5588 11 syndrome syndrome NN cord-006870-f5w6fw6q 5588 12 and and CC cord-006870-f5w6fw6q 5588 13 epilepsy epilepsy NN cord-006870-f5w6fw6q 5588 14 presented present VBN cord-006870-f5w6fw6q 5588 15 to to IN cord-006870-f5w6fw6q 5588 16 the the DT cord-006870-f5w6fw6q 5588 17 emergency emergency NN cord-006870-f5w6fw6q 5588 18 department department NN cord-006870-f5w6fw6q 5588 19 after after IN cord-006870-f5w6fw6q 5588 20 a a DT cord-006870-f5w6fw6q 5588 21 prolonged prolong VBN cord-006870-f5w6fw6q 5588 22 convulsive convulsive JJ cord-006870-f5w6fw6q 5588 23 seizure seizure NN cord-006870-f5w6fw6q 5588 24 . . . cord-006870-f5w6fw6q 5589 1 She -PRON- PRP cord-006870-f5w6fw6q 5589 2 received receive VBD cord-006870-f5w6fw6q 5589 3 2 2 CD cord-006870-f5w6fw6q 5589 4 doses dose NNS cord-006870-f5w6fw6q 5589 5 of of IN cord-006870-f5w6fw6q 5589 6 2 2 CD cord-006870-f5w6fw6q 5589 7 mg mg NNP cord-006870-f5w6fw6q 5589 8 lorazepam lorazepam NN cord-006870-f5w6fw6q 5589 9 and and CC cord-006870-f5w6fw6q 5589 10 levatiracetam levatiracetam VBZ cord-006870-f5w6fw6q 5589 11 6.7 6.7 CD cord-006870-f5w6fw6q 5589 12 mg mg NNP cord-006870-f5w6fw6q 5589 13 / / SYM cord-006870-f5w6fw6q 5589 14 kg kg NN cord-006870-f5w6fw6q 5589 15 with with IN cord-006870-f5w6fw6q 5589 16 cessation cessation NN cord-006870-f5w6fw6q 5589 17 of of IN cord-006870-f5w6fw6q 5589 18 seizure seizure NN cord-006870-f5w6fw6q 5589 19 activity activity NN cord-006870-f5w6fw6q 5589 20 and and CC cord-006870-f5w6fw6q 5589 21 return return VB cord-006870-f5w6fw6q 5589 22 to to IN cord-006870-f5w6fw6q 5589 23 baseline baseline JJ cord-006870-f5w6fw6q 5589 24 neurologic neurologic JJ cord-006870-f5w6fw6q 5589 25 status status NN cord-006870-f5w6fw6q 5589 26 within within IN cord-006870-f5w6fw6q 5589 27 5 5 CD cord-006870-f5w6fw6q 5589 28 hours hour NNS cord-006870-f5w6fw6q 5589 29 of of IN cord-006870-f5w6fw6q 5589 30 the the DT cord-006870-f5w6fw6q 5589 31 initial initial JJ cord-006870-f5w6fw6q 5589 32 event event NN cord-006870-f5w6fw6q 5589 33 . . . cord-006870-f5w6fw6q 5590 1 Head Head NNP cord-006870-f5w6fw6q 5590 2 CT CT NNP cord-006870-f5w6fw6q 5590 3 showed show VBD cord-006870-f5w6fw6q 5590 4 lack lack NN cord-006870-f5w6fw6q 5590 5 of of IN cord-006870-f5w6fw6q 5590 6 sulci sulcus NNS cord-006870-f5w6fw6q 5590 7 throughout throughout IN cord-006870-f5w6fw6q 5590 8 the the DT cord-006870-f5w6fw6q 5590 9 cerebral cerebral JJ cord-006870-f5w6fw6q 5590 10 hemispheres hemisphere NNS cord-006870-f5w6fw6q 5590 11 and and CC cord-006870-f5w6fw6q 5590 12 basilar basilar JJ cord-006870-f5w6fw6q 5590 13 cistern cistern JJ cord-006870-f5w6fw6q 5590 14 effacement effacement NN cord-006870-f5w6fw6q 5590 15 despite despite IN cord-006870-f5w6fw6q 5590 16 being be VBG cord-006870-f5w6fw6q 5590 17 at at IN cord-006870-f5w6fw6q 5590 18 her -PRON- PRP$ cord-006870-f5w6fw6q 5590 19 baseline baseline JJ cord-006870-f5w6fw6q 5590 20 neurologic neurologic JJ cord-006870-f5w6fw6q 5590 21 status status NN cord-006870-f5w6fw6q 5590 22 . . . cord-006870-f5w6fw6q 5591 1 8 8 CD cord-006870-f5w6fw6q 5591 2 hours hour NNS cord-006870-f5w6fw6q 5591 3 after after IN cord-006870-f5w6fw6q 5591 4 presentation presentation NN cord-006870-f5w6fw6q 5591 5 the the DT cord-006870-f5w6fw6q 5591 6 patient patient NN cord-006870-f5w6fw6q 5591 7 had have VBD cord-006870-f5w6fw6q 5591 8 another another DT cord-006870-f5w6fw6q 5591 9 seizure seizure NN cord-006870-f5w6fw6q 5591 10 , , , cord-006870-f5w6fw6q 5591 11 vomited vomit VBD cord-006870-f5w6fw6q 5591 12 , , , cord-006870-f5w6fw6q 5591 13 was be VBD cord-006870-f5w6fw6q 5591 14 intubated intubate VBN cord-006870-f5w6fw6q 5591 15 and and CC cord-006870-f5w6fw6q 5591 16 an an DT cord-006870-f5w6fw6q 5591 17 additional additional JJ cord-006870-f5w6fw6q 5591 18 15 15 CD cord-006870-f5w6fw6q 5591 19 mg mg NN cord-006870-f5w6fw6q 5591 20 / / SYM cord-006870-f5w6fw6q 5591 21 kg kg NNP cord-006870-f5w6fw6q 5591 22 of of IN cord-006870-f5w6fw6q 5591 23 levatiracetam levatiracetam NNP cord-006870-f5w6fw6q 5591 24 given give VBN cord-006870-f5w6fw6q 5591 25 . . . cord-006870-f5w6fw6q 5592 1 14 14 CD cord-006870-f5w6fw6q 5592 2 hours hour NNS cord-006870-f5w6fw6q 5592 3 after after IN cord-006870-f5w6fw6q 5592 4 presentation presentation NN cord-006870-f5w6fw6q 5592 5 , , , cord-006870-f5w6fw6q 5592 6 the the DT cord-006870-f5w6fw6q 5592 7 patient patient NN cord-006870-f5w6fw6q 5592 8 was be VBD cord-006870-f5w6fw6q 5592 9 admitted admit VBN cord-006870-f5w6fw6q 5592 10 to to IN cord-006870-f5w6fw6q 5592 11 the the DT cord-006870-f5w6fw6q 5592 12 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 5592 13 with with IN cord-006870-f5w6fw6q 5592 14 absent absent JJ cord-006870-f5w6fw6q 5592 15 brainstem brainstem NN cord-006870-f5w6fw6q 5592 16 reflexes reflex NNS cord-006870-f5w6fw6q 5592 17 and and CC cord-006870-f5w6fw6q 5592 18 repeat repeat VB cord-006870-f5w6fw6q 5592 19 head head NN cord-006870-f5w6fw6q 5592 20 CT CT NNP cord-006870-f5w6fw6q 5592 21 with with IN cord-006870-f5w6fw6q 5592 22 worsened worsen VBN cord-006870-f5w6fw6q 5592 23 cerebral cerebral JJ cord-006870-f5w6fw6q 5592 24 edema edema NN cord-006870-f5w6fw6q 5592 25 and and CC cord-006870-f5w6fw6q 5592 26 tonsillar tonsillar JJ cord-006870-f5w6fw6q 5592 27 herniation herniation NN cord-006870-f5w6fw6q 5592 28 . . . cord-006870-f5w6fw6q 5593 1 Formal formal JJ cord-006870-f5w6fw6q 5593 2 brain brain NN cord-006870-f5w6fw6q 5593 3 death death NN cord-006870-f5w6fw6q 5593 4 testing testing NN cord-006870-f5w6fw6q 5593 5 was be VBD cord-006870-f5w6fw6q 5593 6 performed perform VBN cord-006870-f5w6fw6q 5593 7 approximately approximately RB cord-006870-f5w6fw6q 5593 8 24 24 CD cord-006870-f5w6fw6q 5593 9 hours hour NNS cord-006870-f5w6fw6q 5593 10 after after IN cord-006870-f5w6fw6q 5593 11 the the DT cord-006870-f5w6fw6q 5593 12 patient patient NN cord-006870-f5w6fw6q 5593 13 's 's POS cord-006870-f5w6fw6q 5593 14 initial initial JJ cord-006870-f5w6fw6q 5593 15 presentation presentation NN cord-006870-f5w6fw6q 5593 16 . . . cord-006870-f5w6fw6q 5594 1 Seizures seizure NNS cord-006870-f5w6fw6q 5594 2 are be VBP cord-006870-f5w6fw6q 5594 3 known know VBN cord-006870-f5w6fw6q 5594 4 to to TO cord-006870-f5w6fw6q 5594 5 cause cause VB cord-006870-f5w6fw6q 5594 6 a a DT cord-006870-f5w6fw6q 5594 7 hypermetabolic hypermetabolic NN cord-006870-f5w6fw6q 5594 8 state state NN cord-006870-f5w6fw6q 5594 9 in in IN cord-006870-f5w6fw6q 5594 10 the the DT cord-006870-f5w6fw6q 5594 11 brain brain NN cord-006870-f5w6fw6q 5594 12 . . . cord-006870-f5w6fw6q 5595 1 Uncontrolled uncontrolled JJ cord-006870-f5w6fw6q 5595 2 neuronal neuronal JJ cord-006870-f5w6fw6q 5595 3 firing firing NN cord-006870-f5w6fw6q 5595 4 leads lead NNS cord-006870-f5w6fw6q 5595 5 to to IN cord-006870-f5w6fw6q 5595 6 hyperemia hyperemia NN cord-006870-f5w6fw6q 5595 7 , , , cord-006870-f5w6fw6q 5595 8 failure failure NN cord-006870-f5w6fw6q 5595 9 of of IN cord-006870-f5w6fw6q 5595 10 Na+/K+ Na+/K+ NNP cord-006870-f5w6fw6q 5595 11 ATP ATP NNP cord-006870-f5w6fw6q 5595 12 pump pump NN cord-006870-f5w6fw6q 5595 13 , , , cord-006870-f5w6fw6q 5595 14 increased increase VBN cord-006870-f5w6fw6q 5595 15 levels level NNS cord-006870-f5w6fw6q 5595 16 of of IN cord-006870-f5w6fw6q 5595 17 neuronal neuronal JJ cord-006870-f5w6fw6q 5595 18 chloride chloride NN cord-006870-f5w6fw6q 5595 19 , , , cord-006870-f5w6fw6q 5595 20 and and CC cord-006870-f5w6fw6q 5595 21 inability inability NN cord-006870-f5w6fw6q 5595 22 for for IN cord-006870-f5w6fw6q 5595 23 cells cell NNS cord-006870-f5w6fw6q 5595 24 to to TO cord-006870-f5w6fw6q 5595 25 maintain maintain VB cord-006870-f5w6fw6q 5595 26 homeostasis homeostasis NN cord-006870-f5w6fw6q 5595 27 . . . cord-006870-f5w6fw6q 5596 1 In in IN cord-006870-f5w6fw6q 5596 2 this this DT cord-006870-f5w6fw6q 5596 3 case case NN cord-006870-f5w6fw6q 5596 4 , , , cord-006870-f5w6fw6q 5596 5 the the DT cord-006870-f5w6fw6q 5596 6 patient patient NN cord-006870-f5w6fw6q 5596 7 's 's POS cord-006870-f5w6fw6q 5596 8 initial initial JJ cord-006870-f5w6fw6q 5596 9 head head NN cord-006870-f5w6fw6q 5596 10 CT CT NNP cord-006870-f5w6fw6q 5596 11 showed show VBD cord-006870-f5w6fw6q 5596 12 cerebral cerebral JJ cord-006870-f5w6fw6q 5596 13 edema edema NN cord-006870-f5w6fw6q 5596 14 , , , cord-006870-f5w6fw6q 5596 15 likely likely RB cord-006870-f5w6fw6q 5596 16 from from IN cord-006870-f5w6fw6q 5596 17 prolonged prolong VBN cord-006870-f5w6fw6q 5596 18 seizure seizure NN cord-006870-f5w6fw6q 5596 19 activity activity NN cord-006870-f5w6fw6q 5596 20 . . . cord-006870-f5w6fw6q 5597 1 Once once RB cord-006870-f5w6fw6q 5597 2 the the DT cord-006870-f5w6fw6q 5597 3 second second JJ cord-006870-f5w6fw6q 5597 4 convulsive convulsive JJ cord-006870-f5w6fw6q 5597 5 seizure seizure NN cord-006870-f5w6fw6q 5597 6 occurred occur VBD cord-006870-f5w6fw6q 5597 7 , , , cord-006870-f5w6fw6q 5597 8 a a DT cord-006870-f5w6fw6q 5597 9 period period NN cord-006870-f5w6fw6q 5597 10 of of IN cord-006870-f5w6fw6q 5597 11 pre pre JJ cord-006870-f5w6fw6q 5597 12 - - JJ cord-006870-f5w6fw6q 5597 13 intubation intubation JJ cord-006870-f5w6fw6q 5597 14 hypoxemia hypoxemia NN cord-006870-f5w6fw6q 5597 15 coupled couple VBN cord-006870-f5w6fw6q 5597 16 with with IN cord-006870-f5w6fw6q 5597 17 post post JJ cord-006870-f5w6fw6q 5597 18 - - JJ cord-006870-f5w6fw6q 5597 19 intubation intubation JJ cord-006870-f5w6fw6q 5597 20 hypotension hypotension NN cord-006870-f5w6fw6q 5597 21 allowed allow VBN cord-006870-f5w6fw6q 5597 22 for for IN cord-006870-f5w6fw6q 5597 23 progression progression NN cord-006870-f5w6fw6q 5597 24 of of IN cord-006870-f5w6fw6q 5597 25 cerebral cerebral JJ cord-006870-f5w6fw6q 5597 26 edema edema NN cord-006870-f5w6fw6q 5597 27 in in IN cord-006870-f5w6fw6q 5597 28 an an DT cord-006870-f5w6fw6q 5597 29 already already RB cord-006870-f5w6fw6q 5597 30 compromised compromise VBN cord-006870-f5w6fw6q 5597 31 brain brain NN cord-006870-f5w6fw6q 5597 32 ; ; : cord-006870-f5w6fw6q 5597 33 similar similar JJ cord-006870-f5w6fw6q 5597 34 to to IN cord-006870-f5w6fw6q 5597 35 what what WP cord-006870-f5w6fw6q 5597 36 is be VBZ cord-006870-f5w6fw6q 5597 37 seen see VBN cord-006870-f5w6fw6q 5597 38 in in IN cord-006870-f5w6fw6q 5597 39 post post JJ cord-006870-f5w6fw6q 5597 40 - - JJ cord-006870-f5w6fw6q 5597 41 cardiac cardiac JJ cord-006870-f5w6fw6q 5597 42 arrest arrest NN cord-006870-f5w6fw6q 5597 43 and and CC cord-006870-f5w6fw6q 5597 44 traumatic traumatic JJ cord-006870-f5w6fw6q 5597 45 brain brain NN cord-006870-f5w6fw6q 5597 46 injury injury NN cord-006870-f5w6fw6q 5597 47 . . . cord-006870-f5w6fw6q 5598 1 This this DT cord-006870-f5w6fw6q 5598 2 case case NN cord-006870-f5w6fw6q 5598 3 illustrates illustrate VBZ cord-006870-f5w6fw6q 5598 4 the the DT cord-006870-f5w6fw6q 5598 5 importance importance NN cord-006870-f5w6fw6q 5598 6 of of IN cord-006870-f5w6fw6q 5598 7 controlling control VBG cord-006870-f5w6fw6q 5598 8 for for IN cord-006870-f5w6fw6q 5598 9 factors factor NNS cord-006870-f5w6fw6q 5598 10 that that WDT cord-006870-f5w6fw6q 5598 11 can can MD cord-006870-f5w6fw6q 5598 12 contribute contribute VB cord-006870-f5w6fw6q 5598 13 to to IN cord-006870-f5w6fw6q 5598 14 secondary secondary JJ cord-006870-f5w6fw6q 5598 15 brain brain NN cord-006870-f5w6fw6q 5598 16 injury injury NN cord-006870-f5w6fw6q 5598 17 in in IN cord-006870-f5w6fw6q 5598 18 seizure seizure NN cord-006870-f5w6fw6q 5598 19 patients patient NNS cord-006870-f5w6fw6q 5598 20 . . . cord-006870-f5w6fw6q 5599 1 Posterior posterior JJ cord-006870-f5w6fw6q 5599 2 reversible reversible JJ cord-006870-f5w6fw6q 5599 3 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5599 4 syndrome syndrome NN cord-006870-f5w6fw6q 5599 5 ( ( -LRB- cord-006870-f5w6fw6q 5599 6 PRES PRES NNP cord-006870-f5w6fw6q 5599 7 ) ) -RRB- cord-006870-f5w6fw6q 5599 8 is be VBZ cord-006870-f5w6fw6q 5599 9 a a DT cord-006870-f5w6fw6q 5599 10 clinico clinico NN cord-006870-f5w6fw6q 5599 11 - - HYPH cord-006870-f5w6fw6q 5599 12 radiographic radiographic JJ cord-006870-f5w6fw6q 5599 13 syndrome syndrome NN cord-006870-f5w6fw6q 5599 14 characterized characterize VBN cord-006870-f5w6fw6q 5599 15 by by IN cord-006870-f5w6fw6q 5599 16 seizure seizure NN cord-006870-f5w6fw6q 5599 17 , , , cord-006870-f5w6fw6q 5599 18 headache headache NN cord-006870-f5w6fw6q 5599 19 , , , cord-006870-f5w6fw6q 5599 20 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5599 21 and and CC cord-006870-f5w6fw6q 5599 22 neuroimaging neuroimage VBG cord-006870-f5w6fw6q 5599 23 findings finding NNS cord-006870-f5w6fw6q 5599 24 of of IN cord-006870-f5w6fw6q 5599 25 symmetric symmetric JJ cord-006870-f5w6fw6q 5599 26 white white JJ cord-006870-f5w6fw6q 5599 27 matter matter NN cord-006870-f5w6fw6q 5599 28 edema edema NN cord-006870-f5w6fw6q 5599 29 in in IN cord-006870-f5w6fw6q 5599 30 the the DT cord-006870-f5w6fw6q 5599 31 posterior posterior JJ cord-006870-f5w6fw6q 5599 32 cerebral cerebral JJ cord-006870-f5w6fw6q 5599 33 hemispheres hemisphere NNS cord-006870-f5w6fw6q 5599 34 . . . cord-006870-f5w6fw6q 5600 1 Cerebellar cerebellar JJ cord-006870-f5w6fw6q 5600 2 and and CC cord-006870-f5w6fw6q 5600 3 brainstem brainstem NN cord-006870-f5w6fw6q 5600 4 involvement involvement NN cord-006870-f5w6fw6q 5600 5 occurs occur VBZ cord-006870-f5w6fw6q 5600 6 rarely rarely RB cord-006870-f5w6fw6q 5600 7 . . . cord-006870-f5w6fw6q 5601 1 Here here RB cord-006870-f5w6fw6q 5601 2 , , , cord-006870-f5w6fw6q 5601 3 we -PRON- PRP cord-006870-f5w6fw6q 5601 4 report report VBP cord-006870-f5w6fw6q 5601 5 a a DT cord-006870-f5w6fw6q 5601 6 patient patient NN cord-006870-f5w6fw6q 5601 7 who who WP cord-006870-f5w6fw6q 5601 8 presented present VBD cord-006870-f5w6fw6q 5601 9 with with IN cord-006870-f5w6fw6q 5601 10 severe severe JJ cord-006870-f5w6fw6q 5601 11 PRES PRES NNP cord-006870-f5w6fw6q 5601 12 complicated complicate VBN cord-006870-f5w6fw6q 5601 13 by by IN cord-006870-f5w6fw6q 5601 14 diffuse diffuse JJ cord-006870-f5w6fw6q 5601 15 cerebellar cerebellar JJ cord-006870-f5w6fw6q 5601 16 edema edema NN cord-006870-f5w6fw6q 5601 17 and and CC cord-006870-f5w6fw6q 5601 18 obstructive obstructive JJ cord-006870-f5w6fw6q 5601 19 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5601 20 requiring require VBG cord-006870-f5w6fw6q 5601 21 decompression decompression NN cord-006870-f5w6fw6q 5601 22 with with IN cord-006870-f5w6fw6q 5601 23 ventriculostomy ventriculostomy NN cord-006870-f5w6fw6q 5601 24 placement placement NN cord-006870-f5w6fw6q 5601 25 . . . cord-006870-f5w6fw6q 5602 1 This this DT cord-006870-f5w6fw6q 5602 2 is be VBZ cord-006870-f5w6fw6q 5602 3 a a DT cord-006870-f5w6fw6q 5602 4 case case NN cord-006870-f5w6fw6q 5602 5 report report NN cord-006870-f5w6fw6q 5602 6 from from IN cord-006870-f5w6fw6q 5602 7 a a DT cord-006870-f5w6fw6q 5602 8 tertiary tertiary JJ cord-006870-f5w6fw6q 5602 9 medical medical JJ cord-006870-f5w6fw6q 5602 10 center center NN cord-006870-f5w6fw6q 5602 11 . . . cord-006870-f5w6fw6q 5603 1 A a DT cord-006870-f5w6fw6q 5603 2 23-year 23-year JJ cord-006870-f5w6fw6q 5603 3 - - HYPH cord-006870-f5w6fw6q 5603 4 old old JJ cord-006870-f5w6fw6q 5603 5 woman woman NN cord-006870-f5w6fw6q 5603 6 with with IN cord-006870-f5w6fw6q 5603 7 a a DT cord-006870-f5w6fw6q 5603 8 history history NN cord-006870-f5w6fw6q 5603 9 of of IN cord-006870-f5w6fw6q 5603 10 migraine migraine NN cord-006870-f5w6fw6q 5603 11 presented present VBN cord-006870-f5w6fw6q 5603 12 to to IN cord-006870-f5w6fw6q 5603 13 the the DT cord-006870-f5w6fw6q 5603 14 emergency emergency NN cord-006870-f5w6fw6q 5603 15 room room NN cord-006870-f5w6fw6q 5603 16 with with IN cord-006870-f5w6fw6q 5603 17 2-day 2-day JJ cord-006870-f5w6fw6q 5603 18 history history NN cord-006870-f5w6fw6q 5603 19 of of IN cord-006870-f5w6fw6q 5603 20 fever fever NN cord-006870-f5w6fw6q 5603 21 , , , cord-006870-f5w6fw6q 5603 22 right right JJ cord-006870-f5w6fw6q 5603 23 upper upper JJ cord-006870-f5w6fw6q 5603 24 quadrant quadrant JJ cord-006870-f5w6fw6q 5603 25 abdominal abdominal JJ cord-006870-f5w6fw6q 5603 26 pain pain NN cord-006870-f5w6fw6q 5603 27 , , , cord-006870-f5w6fw6q 5603 28 nausea nausea NN cord-006870-f5w6fw6q 5603 29 and and CC cord-006870-f5w6fw6q 5603 30 vomiting vomiting NN cord-006870-f5w6fw6q 5603 31 . . . cord-006870-f5w6fw6q 5604 1 On on IN cord-006870-f5w6fw6q 5604 2 day day NN cord-006870-f5w6fw6q 5604 3 two two CD cord-006870-f5w6fw6q 5604 4 of of IN cord-006870-f5w6fw6q 5604 5 hospitalization hospitalization NN cord-006870-f5w6fw6q 5604 6 , , , cord-006870-f5w6fw6q 5604 7 the the DT cord-006870-f5w6fw6q 5604 8 patient patient NN cord-006870-f5w6fw6q 5604 9 developed develop VBD cord-006870-f5w6fw6q 5604 10 worsening worsen VBG cord-006870-f5w6fw6q 5604 11 headache headache NN cord-006870-f5w6fw6q 5604 12 , , , cord-006870-f5w6fw6q 5604 13 dizziness dizziness NN cord-006870-f5w6fw6q 5604 14 and and CC cord-006870-f5w6fw6q 5604 15 lethargy lethargy NN cord-006870-f5w6fw6q 5604 16 and and CC cord-006870-f5w6fw6q 5604 17 her -PRON- PRP$ cord-006870-f5w6fw6q 5604 18 blood blood NN cord-006870-f5w6fw6q 5604 19 pressure pressure NN cord-006870-f5w6fw6q 5604 20 was be VBD cord-006870-f5w6fw6q 5604 21 elevated elevate VBN cord-006870-f5w6fw6q 5604 22 to to IN cord-006870-f5w6fw6q 5605 1 188/93 188/93 CD cord-006870-f5w6fw6q 5605 2 mmHg mmHg NNP cord-006870-f5w6fw6q 5605 3 . . NNP cord-006870-f5w6fw6q 5605 4 CT CT NNP cord-006870-f5w6fw6q 5605 5 of of IN cord-006870-f5w6fw6q 5605 6 the the DT cord-006870-f5w6fw6q 5605 7 brain brain NN cord-006870-f5w6fw6q 5605 8 showed show VBD cord-006870-f5w6fw6q 5605 9 cerebellar cerebellar JJ cord-006870-f5w6fw6q 5605 10 edema edema NN cord-006870-f5w6fw6q 5605 11 and and CC cord-006870-f5w6fw6q 5605 12 bilateral bilateral JJ cord-006870-f5w6fw6q 5605 13 occipital occipital JJ cord-006870-f5w6fw6q 5605 14 lobes lobe NNS cord-006870-f5w6fw6q 5605 15 with with IN cord-006870-f5w6fw6q 5605 16 effacement effacement NN cord-006870-f5w6fw6q 5605 17 of of IN cord-006870-f5w6fw6q 5605 18 the the DT cord-006870-f5w6fw6q 5605 19 fourth fourth JJ cord-006870-f5w6fw6q 5605 20 ventricles ventricle NNS cord-006870-f5w6fw6q 5605 21 and and CC cord-006870-f5w6fw6q 5605 22 associated associated JJ cord-006870-f5w6fw6q 5605 23 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5605 24 involving involve VBG cord-006870-f5w6fw6q 5605 25 the the DT cord-006870-f5w6fw6q 5605 26 lateral lateral JJ cord-006870-f5w6fw6q 5605 27 and and CC cord-006870-f5w6fw6q 5605 28 third third JJ cord-006870-f5w6fw6q 5605 29 ventricle ventricle NN cord-006870-f5w6fw6q 5605 30 . . . cord-006870-f5w6fw6q 5606 1 MRI MRI NNP cord-006870-f5w6fw6q 5606 2 obtained obtain VBD cord-006870-f5w6fw6q 5606 3 post post RB cord-006870-f5w6fw6q 5606 4 - - JJ cord-006870-f5w6fw6q 5606 5 operatively operatively RB cord-006870-f5w6fw6q 5606 6 revealed reveal VBN cord-006870-f5w6fw6q 5606 7 T2-weighted T2-weighted NNP cord-006870-f5w6fw6q 5606 8 / / SYM cord-006870-f5w6fw6q 5606 9 FLAIR flair NN cord-006870-f5w6fw6q 5606 10 diffuse diffuse NN cord-006870-f5w6fw6q 5606 11 hyperintensities hyperintensitie NNS cord-006870-f5w6fw6q 5606 12 in in IN cord-006870-f5w6fw6q 5606 13 the the DT cord-006870-f5w6fw6q 5606 14 parietal parietal JJ cord-006870-f5w6fw6q 5606 15 , , , cord-006870-f5w6fw6q 5606 16 occipital occipital JJ cord-006870-f5w6fw6q 5606 17 lobes lobe NNS cord-006870-f5w6fw6q 5606 18 and and CC cord-006870-f5w6fw6q 5606 19 cerebellum cerebellum NN cord-006870-f5w6fw6q 5606 20 . . . cord-006870-f5w6fw6q 5607 1 There there EX cord-006870-f5w6fw6q 5607 2 was be VBD cord-006870-f5w6fw6q 5607 3 no no DT cord-006870-f5w6fw6q 5607 4 mass mass JJ cord-006870-f5w6fw6q 5607 5 lesion lesion NN cord-006870-f5w6fw6q 5607 6 or or CC cord-006870-f5w6fw6q 5607 7 restricted restrict VBN cord-006870-f5w6fw6q 5607 8 diffusion diffusion NN cord-006870-f5w6fw6q 5607 9 in in IN cord-006870-f5w6fw6q 5607 10 diffusion diffusion NN cord-006870-f5w6fw6q 5607 11 weighted weight VBN cord-006870-f5w6fw6q 5607 12 images image NNS cord-006870-f5w6fw6q 5607 13 ( ( -LRB- cord-006870-f5w6fw6q 5607 14 DWI DWI NNP cord-006870-f5w6fw6q 5607 15 ) ) -RRB- cord-006870-f5w6fw6q 5607 16 suggestive suggestive JJ cord-006870-f5w6fw6q 5607 17 of of IN cord-006870-f5w6fw6q 5607 18 acute acute JJ cord-006870-f5w6fw6q 5607 19 infarction infarction NN cord-006870-f5w6fw6q 5607 20 . . . cord-006870-f5w6fw6q 5608 1 Cerebellar cerebellar JJ cord-006870-f5w6fw6q 5608 2 edema edema NN cord-006870-f5w6fw6q 5608 3 with with IN cord-006870-f5w6fw6q 5608 4 compression compression NN cord-006870-f5w6fw6q 5608 5 of of IN cord-006870-f5w6fw6q 5608 6 the the DT cord-006870-f5w6fw6q 5608 7 fourth fourth JJ cord-006870-f5w6fw6q 5608 8 ventricles ventricle NNS cord-006870-f5w6fw6q 5608 9 with with IN cord-006870-f5w6fw6q 5608 10 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5608 11 was be VBD cord-006870-f5w6fw6q 5608 12 slightly slightly RB cord-006870-f5w6fw6q 5608 13 improved improve VBN cord-006870-f5w6fw6q 5608 14 status status NN cord-006870-f5w6fw6q 5608 15 post post NN cord-006870-f5w6fw6q 5608 16 interval interval NN cord-006870-f5w6fw6q 5608 17 ventricular ventricular JJ cord-006870-f5w6fw6q 5608 18 drain drain NN cord-006870-f5w6fw6q 5608 19 placement placement NN cord-006870-f5w6fw6q 5608 20 . . . cord-006870-f5w6fw6q 5609 1 Ventriculostomy Ventriculostomy NNP cord-006870-f5w6fw6q 5609 2 was be VBD cord-006870-f5w6fw6q 5609 3 weaned wean VBN cord-006870-f5w6fw6q 5609 4 off off RP cord-006870-f5w6fw6q 5609 5 over over IN cord-006870-f5w6fw6q 5609 6 the the DT cord-006870-f5w6fw6q 5609 7 course course NN cord-006870-f5w6fw6q 5609 8 of of IN cord-006870-f5w6fw6q 5609 9 seven seven CD cord-006870-f5w6fw6q 5609 10 days day NNS cord-006870-f5w6fw6q 5609 11 . . . cord-006870-f5w6fw6q 5610 1 Follow follow VB cord-006870-f5w6fw6q 5610 2 up up RP cord-006870-f5w6fw6q 5610 3 MRI MRI NNP cord-006870-f5w6fw6q 5610 4 showed show VBD cord-006870-f5w6fw6q 5610 5 improvement improvement NN cord-006870-f5w6fw6q 5610 6 of of IN cord-006870-f5w6fw6q 5610 7 the the DT cord-006870-f5w6fw6q 5610 8 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5610 9 with with IN cord-006870-f5w6fw6q 5610 10 decreased decrease VBD cord-006870-f5w6fw6q 5610 11 in in IN cord-006870-f5w6fw6q 5610 12 T2-weighted t2-weighted JJ cord-006870-f5w6fw6q 5610 13 hyperintensities hyperintensitie NNS cord-006870-f5w6fw6q 5610 14 in in IN cord-006870-f5w6fw6q 5610 15 posterior posterior JJ cord-006870-f5w6fw6q 5610 16 parietal parietal JJ cord-006870-f5w6fw6q 5610 17 and and CC cord-006870-f5w6fw6q 5610 18 occipital occipital JJ cord-006870-f5w6fw6q 5610 19 lobes lobe NNS cord-006870-f5w6fw6q 5610 20 as as RB cord-006870-f5w6fw6q 5610 21 well well RB cord-006870-f5w6fw6q 5610 22 as as IN cord-006870-f5w6fw6q 5610 23 within within IN cord-006870-f5w6fw6q 5610 24 the the DT cord-006870-f5w6fw6q 5610 25 cerebellum cerebellum NN cord-006870-f5w6fw6q 5610 26 . . . cord-006870-f5w6fw6q 5611 1 Severe severe JJ cord-006870-f5w6fw6q 5611 2 cerebellar cerebellar JJ cord-006870-f5w6fw6q 5611 3 edema edema NN cord-006870-f5w6fw6q 5611 4 with with IN cord-006870-f5w6fw6q 5611 5 obstructive obstructive JJ cord-006870-f5w6fw6q 5611 6 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5611 7 is be VBZ cord-006870-f5w6fw6q 5611 8 an an DT cord-006870-f5w6fw6q 5611 9 exceedingly exceedingly RB cord-006870-f5w6fw6q 5611 10 rare rare JJ cord-006870-f5w6fw6q 5611 11 complication complication NN cord-006870-f5w6fw6q 5611 12 of of IN cord-006870-f5w6fw6q 5611 13 PRES PRES NNP cord-006870-f5w6fw6q 5611 14 ; ; : cord-006870-f5w6fw6q 5611 15 however however RB cord-006870-f5w6fw6q 5611 16 , , , cord-006870-f5w6fw6q 5611 17 prompt prompt JJ cord-006870-f5w6fw6q 5611 18 recognition recognition NN cord-006870-f5w6fw6q 5611 19 and and CC cord-006870-f5w6fw6q 5611 20 surgical surgical JJ cord-006870-f5w6fw6q 5611 21 decompression decompression NN cord-006870-f5w6fw6q 5611 22 in in IN cord-006870-f5w6fw6q 5611 23 addition addition NN cord-006870-f5w6fw6q 5611 24 to to IN cord-006870-f5w6fw6q 5611 25 usual usual JJ cord-006870-f5w6fw6q 5611 26 medical medical JJ cord-006870-f5w6fw6q 5611 27 management management NN cord-006870-f5w6fw6q 5611 28 is be VBZ cord-006870-f5w6fw6q 5611 29 critical critical JJ cord-006870-f5w6fw6q 5611 30 to to TO cord-006870-f5w6fw6q 5611 31 achieve achieve VB cord-006870-f5w6fw6q 5611 32 a a DT cord-006870-f5w6fw6q 5611 33 favorable favorable JJ cord-006870-f5w6fw6q 5611 34 outcome outcome NN cord-006870-f5w6fw6q 5611 35 . . . cord-006870-f5w6fw6q 5612 1 While while IN cord-006870-f5w6fw6q 5612 2 obstructive obstructive JJ cord-006870-f5w6fw6q 5612 3 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5612 4 may may MD cord-006870-f5w6fw6q 5612 5 be be VB cord-006870-f5w6fw6q 5612 6 successfully successfully RB cord-006870-f5w6fw6q 5612 7 treated treat VBN cord-006870-f5w6fw6q 5612 8 with with IN cord-006870-f5w6fw6q 5612 9 medical medical JJ cord-006870-f5w6fw6q 5612 10 management management NN cord-006870-f5w6fw6q 5612 11 and and CC cord-006870-f5w6fw6q 5612 12 blood blood NN cord-006870-f5w6fw6q 5612 13 pressure pressure NN cord-006870-f5w6fw6q 5612 14 reduction reduction NN cord-006870-f5w6fw6q 5612 15 , , , cord-006870-f5w6fw6q 5612 16 this this DT cord-006870-f5w6fw6q 5612 17 case case NN cord-006870-f5w6fw6q 5612 18 emphasizes emphasize VBZ cord-006870-f5w6fw6q 5612 19 that that IN cord-006870-f5w6fw6q 5612 20 clinical clinical JJ cord-006870-f5w6fw6q 5612 21 evidence evidence NN cord-006870-f5w6fw6q 5612 22 of of IN cord-006870-f5w6fw6q 5612 23 brain brain NN cord-006870-f5w6fw6q 5612 24 herniation herniation NN cord-006870-f5w6fw6q 5612 25 should should MD cord-006870-f5w6fw6q 5612 26 prompt prompt VB cord-006870-f5w6fw6q 5612 27 immediate immediate JJ cord-006870-f5w6fw6q 5612 28 consideration consideration NN cord-006870-f5w6fw6q 5612 29 for for IN cord-006870-f5w6fw6q 5612 30 emergent emergent JJ cord-006870-f5w6fw6q 5612 31 ventriculostomy ventriculostomy NN cord-006870-f5w6fw6q 5612 32 placement placement NN cord-006870-f5w6fw6q 5612 33 or or CC cord-006870-f5w6fw6q 5612 34 surgical surgical JJ cord-006870-f5w6fw6q 5612 35 decompression decompression NN cord-006870-f5w6fw6q 5612 36 to to TO cord-006870-f5w6fw6q 5612 37 redirect redirect VB cord-006870-f5w6fw6q 5612 38 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 5612 39 fluid fluid NN cord-006870-f5w6fw6q 5612 40 and and CC cord-006870-f5w6fw6q 5612 41 reduce reduce VB cord-006870-f5w6fw6q 5612 42 intracranial intracranial JJ cord-006870-f5w6fw6q 5612 43 pressure pressure NN cord-006870-f5w6fw6q 5612 44 . . . cord-006870-f5w6fw6q 5613 1 One one CD cord-006870-f5w6fw6q 5613 2 of of IN cord-006870-f5w6fw6q 5613 3 the the DT cord-006870-f5w6fw6q 5613 4 biggest big JJS cord-006870-f5w6fw6q 5613 5 uses use NNS cord-006870-f5w6fw6q 5613 6 of of IN cord-006870-f5w6fw6q 5613 7 QEEG QEEG NNP cord-006870-f5w6fw6q 5613 8 is be VBZ cord-006870-f5w6fw6q 5613 9 the the DT cord-006870-f5w6fw6q 5613 10 alpha alpha NN cord-006870-f5w6fw6q 5613 11 delta delta NN cord-006870-f5w6fw6q 5613 12 ratio ratio NN cord-006870-f5w6fw6q 5613 13 ( ( -LRB- cord-006870-f5w6fw6q 5613 14 ADR ADR NNP cord-006870-f5w6fw6q 5613 15 ) ) -RRB- cord-006870-f5w6fw6q 5613 16 . . . cord-006870-f5w6fw6q 5614 1 ADR ADR NNP cord-006870-f5w6fw6q 5614 2 drops drop NNS cord-006870-f5w6fw6q 5614 3 of of IN cord-006870-f5w6fw6q 5614 4 20 20 CD cord-006870-f5w6fw6q 5614 5 % % NN cord-006870-f5w6fw6q 5614 6 from from IN cord-006870-f5w6fw6q 5614 7 baseline baseline NN cord-006870-f5w6fw6q 5614 8 are be VBP cord-006870-f5w6fw6q 5614 9 associated associate VBN cord-006870-f5w6fw6q 5614 10 with with IN cord-006870-f5w6fw6q 5614 11 vasospasm vasospasm NN cord-006870-f5w6fw6q 5614 12 ( ( -LRB- cord-006870-f5w6fw6q 5614 13 VSP VSP NNP cord-006870-f5w6fw6q 5614 14 / / SYM cord-006870-f5w6fw6q 5614 15 DIND DIND NNP cord-006870-f5w6fw6q 5614 16 ) ) -RRB- cord-006870-f5w6fw6q 5614 17 . . . cord-006870-f5w6fw6q 5615 1 We -PRON- PRP cord-006870-f5w6fw6q 5615 2 describe describe VBP cord-006870-f5w6fw6q 5615 3 a a DT cord-006870-f5w6fw6q 5615 4 case case NN cord-006870-f5w6fw6q 5615 5 in in IN cord-006870-f5w6fw6q 5615 6 which which WDT cord-006870-f5w6fw6q 5615 7 subtle subtle JJ cord-006870-f5w6fw6q 5615 8 QEEG QEEG NNP cord-006870-f5w6fw6q 5615 9 ADR adr NN cord-006870-f5w6fw6q 5615 10 change change NN cord-006870-f5w6fw6q 5615 11 occurred occur VBD cord-006870-f5w6fw6q 5615 12 in in IN cord-006870-f5w6fw6q 5615 13 a a DT cord-006870-f5w6fw6q 5615 14 poor poor JJ cord-006870-f5w6fw6q 5615 15 grade grade NN cord-006870-f5w6fw6q 5615 16 SAH sah NN cord-006870-f5w6fw6q 5615 17 patient patient NN cord-006870-f5w6fw6q 5615 18 over over IN cord-006870-f5w6fw6q 5615 19 a a DT cord-006870-f5w6fw6q 5615 20 number number NN cord-006870-f5w6fw6q 5615 21 of of IN cord-006870-f5w6fw6q 5615 22 days day NNS cord-006870-f5w6fw6q 5615 23 , , , cord-006870-f5w6fw6q 5615 24 making make VBG cord-006870-f5w6fw6q 5615 25 it -PRON- PRP cord-006870-f5w6fw6q 5615 26 challenging challenging JJ cord-006870-f5w6fw6q 5615 27 to to TO cord-006870-f5w6fw6q 5615 28 detect detect VB cord-006870-f5w6fw6q 5615 29 an an DT cord-006870-f5w6fw6q 5615 30 acute acute JJ cord-006870-f5w6fw6q 5615 31 ADR adr NN cord-006870-f5w6fw6q 5615 32 drop drop NN cord-006870-f5w6fw6q 5615 33 . . . cord-006870-f5w6fw6q 5616 1 This this DT cord-006870-f5w6fw6q 5616 2 is be VBZ cord-006870-f5w6fw6q 5616 3 a a DT cord-006870-f5w6fw6q 5616 4 case case NN cord-006870-f5w6fw6q 5616 5 report report NN cord-006870-f5w6fw6q 5616 6 and and CC cord-006870-f5w6fw6q 5616 7 literature literature NN cord-006870-f5w6fw6q 5616 8 review review NN cord-006870-f5w6fw6q 5616 9 . . . cord-006870-f5w6fw6q 5617 1 This this DT cord-006870-f5w6fw6q 5617 2 study study NN cord-006870-f5w6fw6q 5617 3 also also RB cord-006870-f5w6fw6q 5617 4 compared compare VBD cord-006870-f5w6fw6q 5617 5 hemispheric hemispheric JJ cord-006870-f5w6fw6q 5617 6 ADR ADR NNP cord-006870-f5w6fw6q 5617 7 values value NNS cord-006870-f5w6fw6q 5617 8 against against IN cord-006870-f5w6fw6q 5617 9 the the DT cord-006870-f5w6fw6q 5617 10 MCA MCA NNP cord-006870-f5w6fw6q 5617 11 values value NNS cord-006870-f5w6fw6q 5617 12 by by IN cord-006870-f5w6fw6q 5617 13 TCD TCD NNP cord-006870-f5w6fw6q 5617 14 , , , cord-006870-f5w6fw6q 5617 15 DSA DSA NNP cord-006870-f5w6fw6q 5617 16 , , , cord-006870-f5w6fw6q 5617 17 CTA CTA NNP cord-006870-f5w6fw6q 5617 18 and and CC cord-006870-f5w6fw6q 5617 19 clinical clinical JJ cord-006870-f5w6fw6q 5617 20 exam exam NN cord-006870-f5w6fw6q 5617 21 . . . cord-006870-f5w6fw6q 5618 1 A a DT cord-006870-f5w6fw6q 5618 2 67 67 CD cord-006870-f5w6fw6q 5618 3 year year NN cord-006870-f5w6fw6q 5618 4 old old JJ cord-006870-f5w6fw6q 5618 5 female female NN cord-006870-f5w6fw6q 5618 6 with with IN cord-006870-f5w6fw6q 5618 7 Hunt Hunt NNP cord-006870-f5w6fw6q 5618 8 Hess Hess NNP cord-006870-f5w6fw6q 5618 9 III III NNP cord-006870-f5w6fw6q 5618 10 , , , cord-006870-f5w6fw6q 5618 11 WFNS WFNS NNP cord-006870-f5w6fw6q 5618 12 IV IV NNP cord-006870-f5w6fw6q 5618 13 , , , cord-006870-f5w6fw6q 5618 14 came come VBD cord-006870-f5w6fw6q 5618 15 in in IN cord-006870-f5w6fw6q 5618 16 comatose comatose JJ cord-006870-f5w6fw6q 5618 17 with with IN cord-006870-f5w6fw6q 5618 18 a a DT cord-006870-f5w6fw6q 5618 19 ruptured rupture VBN cord-006870-f5w6fw6q 5618 20 ICA ICA NNP cord-006870-f5w6fw6q 5618 21 aneurysm aneurysm NN cord-006870-f5w6fw6q 5618 22 . . . cord-006870-f5w6fw6q 5619 1 Over over IN cord-006870-f5w6fw6q 5619 2 six six CD cord-006870-f5w6fw6q 5619 3 days day NNS cord-006870-f5w6fw6q 5619 4 , , , cord-006870-f5w6fw6q 5619 5 she -PRON- PRP cord-006870-f5w6fw6q 5619 6 developed develop VBD cord-006870-f5w6fw6q 5619 7 refractory refractory JJ cord-006870-f5w6fw6q 5619 8 VSP VSP NNP cord-006870-f5w6fw6q 5619 9 / / SYM cord-006870-f5w6fw6q 5619 10 DIND DIND NNP cord-006870-f5w6fw6q 5619 11 . . . cord-006870-f5w6fw6q 5620 1 The the DT cord-006870-f5w6fw6q 5620 2 patient patient NN cord-006870-f5w6fw6q 5620 3 's 's POS cord-006870-f5w6fw6q 5620 4 ADR ADR NNP cord-006870-f5w6fw6q 5620 5 was be VBD cord-006870-f5w6fw6q 5620 6 gradually gradually RB cord-006870-f5w6fw6q 5620 7 declining decline VBG cord-006870-f5w6fw6q 5620 8 but but CC cord-006870-f5w6fw6q 5620 9 their -PRON- PRP$ cord-006870-f5w6fw6q 5620 10 increased increase VBN cord-006870-f5w6fw6q 5620 11 ICP ICP NNP cord-006870-f5w6fw6q 5620 12 required require VBD cord-006870-f5w6fw6q 5620 13 propofol propofol NN cord-006870-f5w6fw6q 5620 14 sedation sedation NN cord-006870-f5w6fw6q 5620 15 , , , cord-006870-f5w6fw6q 5620 16 which which WDT cord-006870-f5w6fw6q 5620 17 itself -PRON- PRP cord-006870-f5w6fw6q 5620 18 lowers lower VBZ cord-006870-f5w6fw6q 5620 19 ADR ADR NNP cord-006870-f5w6fw6q 5620 20 . . . cord-006870-f5w6fw6q 5621 1 Re re NN cord-006870-f5w6fw6q 5621 2 - - NN cord-006870-f5w6fw6q 5621 3 analysis analysis NN cord-006870-f5w6fw6q 5621 4 over over IN cord-006870-f5w6fw6q 5621 5 multiple multiple JJ cord-006870-f5w6fw6q 5621 6 days day NNS cord-006870-f5w6fw6q 5621 7 had have VBD cord-006870-f5w6fw6q 5621 8 to to TO cord-006870-f5w6fw6q 5621 9 be be VB cord-006870-f5w6fw6q 5621 10 performed perform VBN cord-006870-f5w6fw6q 5621 11 , , , cord-006870-f5w6fw6q 5621 12 and and CC cord-006870-f5w6fw6q 5621 13 that that IN cord-006870-f5w6fw6q 5621 14 re re NN cord-006870-f5w6fw6q 5621 15 - - NN cord-006870-f5w6fw6q 5621 16 analysis analysis NN cord-006870-f5w6fw6q 5621 17 showed show VBD cord-006870-f5w6fw6q 5621 18 a a DT cord-006870-f5w6fw6q 5621 19 gradual gradual JJ cord-006870-f5w6fw6q 5621 20 ADR ADR NNP cord-006870-f5w6fw6q 5621 21 decline decline NN cord-006870-f5w6fw6q 5621 22 preceding precede VBG cord-006870-f5w6fw6q 5621 23 the the DT cord-006870-f5w6fw6q 5621 24 VSP VSP NNP cord-006870-f5w6fw6q 5621 25 / / SYM cord-006870-f5w6fw6q 5621 26 DIND DIND NNP cord-006870-f5w6fw6q 5621 27 . . . cord-006870-f5w6fw6q 5622 1 When when WRB cord-006870-f5w6fw6q 5622 2 looking look VBG cord-006870-f5w6fw6q 5622 3 at at IN cord-006870-f5w6fw6q 5622 4 our -PRON- PRP$ cord-006870-f5w6fw6q 5622 5 cases case NNS cord-006870-f5w6fw6q 5622 6 , , , cord-006870-f5w6fw6q 5622 7 we -PRON- PRP cord-006870-f5w6fw6q 5622 8 found find VBD cord-006870-f5w6fw6q 5622 9 a a DT cord-006870-f5w6fw6q 5622 10 sensitivity sensitivity NN cord-006870-f5w6fw6q 5622 11 and and CC cord-006870-f5w6fw6q 5622 12 specificity specificity NN cord-006870-f5w6fw6q 5622 13 of of IN cord-006870-f5w6fw6q 5622 14 ( ( -LRB- cord-006870-f5w6fw6q 5622 15 40,75 40,75 CD cord-006870-f5w6fw6q 5622 16 % % NN cord-006870-f5w6fw6q 5622 17 ) ) -RRB- cord-006870-f5w6fw6q 5622 18 when when WRB cord-006870-f5w6fw6q 5622 19 using use VBG cord-006870-f5w6fw6q 5622 20 the the DT cord-006870-f5w6fw6q 5622 21 ADR ADR NNP cord-006870-f5w6fw6q 5622 22 nadir nadir NN cord-006870-f5w6fw6q 5622 23 compared compare VBN cord-006870-f5w6fw6q 5622 24 to to IN cord-006870-f5w6fw6q 5622 25 CTA CTA NNP cord-006870-f5w6fw6q 5622 26 / / SYM cord-006870-f5w6fw6q 5622 27 DSA DSA NNP cord-006870-f5w6fw6q 5622 28 . . . cord-006870-f5w6fw6q 5623 1 Recent recent JJ cord-006870-f5w6fw6q 5623 2 publications publication NNS cord-006870-f5w6fw6q 5623 3 have have VBP cord-006870-f5w6fw6q 5623 4 shown show VBN cord-006870-f5w6fw6q 5623 5 the the DT cord-006870-f5w6fw6q 5623 6 ADR ADR NNP cord-006870-f5w6fw6q 5623 7 method method NN cord-006870-f5w6fw6q 5623 8 has have VBZ cord-006870-f5w6fw6q 5623 9 less less JJR cord-006870-f5w6fw6q 5623 10 than than IN cord-006870-f5w6fw6q 5623 11 ideal ideal JJ cord-006870-f5w6fw6q 5623 12 sensitivity sensitivity NN cord-006870-f5w6fw6q 5623 13 and and CC cord-006870-f5w6fw6q 5623 14 specificity specificity NN cord-006870-f5w6fw6q 5623 15 of of IN cord-006870-f5w6fw6q 5623 16 ( ( -LRB- cord-006870-f5w6fw6q 5623 17 65,43 65,43 CD cord-006870-f5w6fw6q 5623 18 % % NN cord-006870-f5w6fw6q 5623 19 ) ) -RRB- cord-006870-f5w6fw6q 5623 20 . . . cord-006870-f5w6fw6q 5624 1 QEEG QEEG NNP cord-006870-f5w6fw6q 5624 2 ADR ADR NNP cord-006870-f5w6fw6q 5624 3 is be VBZ cord-006870-f5w6fw6q 5624 4 a a DT cord-006870-f5w6fw6q 5624 5 useful useful JJ cord-006870-f5w6fw6q 5624 6 multimodal multimodal NN cord-006870-f5w6fw6q 5624 7 monitoring monitoring NN cord-006870-f5w6fw6q 5624 8 parameter parameter NN cord-006870-f5w6fw6q 5624 9 in in IN cord-006870-f5w6fw6q 5624 10 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 5624 11 patients patient NNS cord-006870-f5w6fw6q 5624 12 with with IN cord-006870-f5w6fw6q 5624 13 relatively relatively RB cord-006870-f5w6fw6q 5624 14 good good JJ cord-006870-f5w6fw6q 5624 15 baseline baseline JJ cord-006870-f5w6fw6q 5624 16 ADR ADR NNP cord-006870-f5w6fw6q 5624 17 . . . cord-006870-f5w6fw6q 5625 1 However however RB cord-006870-f5w6fw6q 5625 2 , , , cord-006870-f5w6fw6q 5625 3 its -PRON- PRP$ cord-006870-f5w6fw6q 5625 4 ability ability NN cord-006870-f5w6fw6q 5625 5 to to TO cord-006870-f5w6fw6q 5625 6 detect detect VB cord-006870-f5w6fw6q 5625 7 VSP VSP NNP cord-006870-f5w6fw6q 5625 8 and and CC cord-006870-f5w6fw6q 5625 9 DIND DIND NNP cord-006870-f5w6fw6q 5625 10 in in IN cord-006870-f5w6fw6q 5625 11 poor poor JJ cord-006870-f5w6fw6q 5625 12 grade grade NN cord-006870-f5w6fw6q 5625 13 SAH SAH NNP cord-006870-f5w6fw6q 5625 14 patients patient NNS cord-006870-f5w6fw6q 5625 15 who who WP cord-006870-f5w6fw6q 5625 16 have have VBP cord-006870-f5w6fw6q 5625 17 ADR adr NN cord-006870-f5w6fw6q 5625 18 values value NNS cord-006870-f5w6fw6q 5625 19 that that WDT cord-006870-f5w6fw6q 5625 20 are be VBP cord-006870-f5w6fw6q 5625 21 already already RB cord-006870-f5w6fw6q 5625 22 low low JJ cord-006870-f5w6fw6q 5625 23 ( ( -LRB- cord-006870-f5w6fw6q 5625 24 < < XX cord-006870-f5w6fw6q 5625 25 0.5 0.5 CD cord-006870-f5w6fw6q 5625 26 ) ) -RRB- cord-006870-f5w6fw6q 5625 27 is be VBZ cord-006870-f5w6fw6q 5625 28 challenging challenging JJ cord-006870-f5w6fw6q 5625 29 , , , cord-006870-f5w6fw6q 5625 30 particularly particularly RB cord-006870-f5w6fw6q 5625 31 given give VBN cord-006870-f5w6fw6q 5625 32 the the DT cord-006870-f5w6fw6q 5625 33 confounders confounder NNS cord-006870-f5w6fw6q 5625 34 in in IN cord-006870-f5w6fw6q 5625 35 this this DT cord-006870-f5w6fw6q 5625 36 population population NN cord-006870-f5w6fw6q 5625 37 , , , cord-006870-f5w6fw6q 5625 38 such such JJ cord-006870-f5w6fw6q 5625 39 as as IN cord-006870-f5w6fw6q 5625 40 EEG EEG NNP cord-006870-f5w6fw6q 5625 41 artifact artifact NN cord-006870-f5w6fw6q 5625 42 which which WDT cord-006870-f5w6fw6q 5625 43 artificially artificially RB cord-006870-f5w6fw6q 5625 44 raise raise VBP cord-006870-f5w6fw6q 5625 45 ADR adr NN cord-006870-f5w6fw6q 5625 46 values value NNS cord-006870-f5w6fw6q 5625 47 , , , cord-006870-f5w6fw6q 5625 48 and and CC cord-006870-f5w6fw6q 5625 49 sedation sedation NN cord-006870-f5w6fw6q 5625 50 ( ( -LRB- cord-006870-f5w6fw6q 5625 51 e.g. e.g. RB cord-006870-f5w6fw6q 5625 52 , , , cord-006870-f5w6fw6q 5625 53 propofol propofol NN cord-006870-f5w6fw6q 5625 54 ) ) -RRB- cord-006870-f5w6fw6q 5625 55 which which WDT cord-006870-f5w6fw6q 5625 56 suppress suppress VBP cord-006870-f5w6fw6q 5625 57 ADR adr NN cord-006870-f5w6fw6q 5625 58 values value NNS cord-006870-f5w6fw6q 5625 59 . . . cord-006870-f5w6fw6q 5626 1 Based base VBN cord-006870-f5w6fw6q 5626 2 on on IN cord-006870-f5w6fw6q 5626 3 this this DT cord-006870-f5w6fw6q 5626 4 information information NN cord-006870-f5w6fw6q 5626 5 , , , cord-006870-f5w6fw6q 5626 6 we -PRON- PRP cord-006870-f5w6fw6q 5626 7 would would MD cord-006870-f5w6fw6q 5626 8 suggest suggest VB cord-006870-f5w6fw6q 5626 9 neuroICU neuroICU NNP cord-006870-f5w6fw6q 5626 10 centers center NNS cord-006870-f5w6fw6q 5626 11 carefully carefully RB cord-006870-f5w6fw6q 5626 12 use use VBP cord-006870-f5w6fw6q 5626 13 continuous continuous JJ cord-006870-f5w6fw6q 5626 14 EEG EEG NNP cord-006870-f5w6fw6q 5626 15 monitoring monitoring NN cord-006870-f5w6fw6q 5626 16 for for IN cord-006870-f5w6fw6q 5626 17 other other JJ cord-006870-f5w6fw6q 5626 18 indications indication NNS cord-006870-f5w6fw6q 5626 19 such such JJ cord-006870-f5w6fw6q 5626 20 as as IN cord-006870-f5w6fw6q 5626 21 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 5626 22 seizures seizure NNS cord-006870-f5w6fw6q 5626 23 , , , cord-006870-f5w6fw6q 5626 24 unless unless IN cord-006870-f5w6fw6q 5626 25 they -PRON- PRP cord-006870-f5w6fw6q 5626 26 have have VBP cord-006870-f5w6fw6q 5626 27 sophisticated sophisticated JJ cord-006870-f5w6fw6q 5626 28 bedside bedside NN cord-006870-f5w6fw6q 5626 29 protocols protocol NNS cord-006870-f5w6fw6q 5626 30 about about IN cord-006870-f5w6fw6q 5626 31 sedation sedation NN cord-006870-f5w6fw6q 5626 32 vacation vacation NN cord-006870-f5w6fw6q 5626 33 ( ( -LRB- cord-006870-f5w6fw6q 5626 34 baseline baseline JJ cord-006870-f5w6fw6q 5626 35 daily daily JJ cord-006870-f5w6fw6q 5626 36 ADR ADR NNP cord-006870-f5w6fw6q 5626 37 that that WDT cord-006870-f5w6fw6q 5626 38 is be VBZ cord-006870-f5w6fw6q 5626 39 not not RB cord-006870-f5w6fw6q 5626 40 ) ) -RRB- cord-006870-f5w6fw6q 5626 41 and and CC cord-006870-f5w6fw6q 5626 42 EEG EEG NNP cord-006870-f5w6fw6q 5626 43 department department NN cord-006870-f5w6fw6q 5626 44 resources resource NNS cord-006870-f5w6fw6q 5626 45 ( ( -LRB- cord-006870-f5w6fw6q 5626 46 technicians technician NNS cord-006870-f5w6fw6q 5626 47 who who WP cord-006870-f5w6fw6q 5626 48 can can MD cord-006870-f5w6fw6q 5626 49 fix fix VB cord-006870-f5w6fw6q 5626 50 EEG EEG NNP cord-006870-f5w6fw6q 5626 51 electrode electrode JJ cord-006870-f5w6fw6q 5626 52 artifacts artifact NNS cord-006870-f5w6fw6q 5626 53 ) ) -RRB- cord-006870-f5w6fw6q 5626 54 . . . cord-006870-f5w6fw6q 5627 1 Hypoxic hypoxic JJ cord-006870-f5w6fw6q 5627 2 - - HYPH cord-006870-f5w6fw6q 5627 3 ischemic ischemic JJ cord-006870-f5w6fw6q 5627 4 brain brain NN cord-006870-f5w6fw6q 5627 5 injury injury NN cord-006870-f5w6fw6q 5627 6 is be VBZ cord-006870-f5w6fw6q 5627 7 a a DT cord-006870-f5w6fw6q 5627 8 severe severe JJ cord-006870-f5w6fw6q 5627 9 consequence consequence NN cord-006870-f5w6fw6q 5627 10 of of IN cord-006870-f5w6fw6q 5627 11 global global JJ cord-006870-f5w6fw6q 5627 12 cerebral cerebral JJ cord-006870-f5w6fw6q 5627 13 hypoperfusion hypoperfusion NN cord-006870-f5w6fw6q 5627 14 following follow VBG cord-006870-f5w6fw6q 5627 15 cardiac cardiac JJ cord-006870-f5w6fw6q 5627 16 arrest arrest NN cord-006870-f5w6fw6q 5627 17 . . . cord-006870-f5w6fw6q 5628 1 Brain Brain NNP cord-006870-f5w6fw6q 5628 2 CT CT NNP cord-006870-f5w6fw6q 5628 3 findings finding NNS cord-006870-f5w6fw6q 5628 4 may may MD cord-006870-f5w6fw6q 5628 5 include include VB cord-006870-f5w6fw6q 5628 6 diffuse diffuse VB cord-006870-f5w6fw6q 5628 7 sulcal sulcal JJ cord-006870-f5w6fw6q 5628 8 effacement effacement NN cord-006870-f5w6fw6q 5628 9 , , , cord-006870-f5w6fw6q 5628 10 loss loss NN cord-006870-f5w6fw6q 5628 11 of of IN cord-006870-f5w6fw6q 5628 12 cisternal cisternal JJ cord-006870-f5w6fw6q 5628 13 spaces space NNS cord-006870-f5w6fw6q 5628 14 , , , cord-006870-f5w6fw6q 5628 15 poor poor JJ cord-006870-f5w6fw6q 5628 16 differentiation differentiation NN cord-006870-f5w6fw6q 5628 17 of of IN cord-006870-f5w6fw6q 5628 18 grey grey JJ cord-006870-f5w6fw6q 5628 19 / / SYM cord-006870-f5w6fw6q 5628 20 white white JJ cord-006870-f5w6fw6q 5628 21 matter matter NN cord-006870-f5w6fw6q 5628 22 , , , cord-006870-f5w6fw6q 5628 23 and and CC cord-006870-f5w6fw6q 5628 24 decreased decrease VBD cord-006870-f5w6fw6q 5628 25 densities density NNS cord-006870-f5w6fw6q 5628 26 in in IN cord-006870-f5w6fw6q 5628 27 the the DT cord-006870-f5w6fw6q 5628 28 basal basal NN cord-006870-f5w6fw6q 5628 29 ganglia ganglion NNS cord-006870-f5w6fw6q 5628 30 and and CC cord-006870-f5w6fw6q 5628 31 watershed watershed JJ cord-006870-f5w6fw6q 5628 32 territories territory NNS cord-006870-f5w6fw6q 5628 33 . . . cord-006870-f5w6fw6q 5629 1 The the DT cord-006870-f5w6fw6q 5629 2 connection connection NN cord-006870-f5w6fw6q 5629 3 between between IN cord-006870-f5w6fw6q 5629 4 aggressive aggressive JJ cord-006870-f5w6fw6q 5629 5 resuscitation resuscitation NN cord-006870-f5w6fw6q 5629 6 , , , cord-006870-f5w6fw6q 5629 7 as as IN cord-006870-f5w6fw6q 5629 8 seen see VBN cord-006870-f5w6fw6q 5629 9 with with IN cord-006870-f5w6fw6q 5629 10 in in IN cord-006870-f5w6fw6q 5629 11 - - HYPH cord-006870-f5w6fw6q 5629 12 hospital hospital NN cord-006870-f5w6fw6q 5629 13 cardiac cardiac JJ cord-006870-f5w6fw6q 5629 14 arrest arrest NN cord-006870-f5w6fw6q 5629 15 , , , cord-006870-f5w6fw6q 5629 16 and and CC cord-006870-f5w6fw6q 5629 17 cerebral cerebral JJ cord-006870-f5w6fw6q 5629 18 edema edema NN cord-006870-f5w6fw6q 5629 19 is be VBZ cord-006870-f5w6fw6q 5629 20 unclear unclear JJ cord-006870-f5w6fw6q 5629 21 . . . cord-006870-f5w6fw6q 5630 1 Here here RB cord-006870-f5w6fw6q 5630 2 we -PRON- PRP cord-006870-f5w6fw6q 5630 3 present present VBP cord-006870-f5w6fw6q 5630 4 the the DT cord-006870-f5w6fw6q 5630 5 case case NN cord-006870-f5w6fw6q 5630 6 of of IN cord-006870-f5w6fw6q 5630 7 a a DT cord-006870-f5w6fw6q 5630 8 hemodynamically hemodynamically RB cord-006870-f5w6fw6q 5630 9 unstable unstable JJ cord-006870-f5w6fw6q 5630 10 patient patient NN cord-006870-f5w6fw6q 5630 11 who who WP cord-006870-f5w6fw6q 5630 12 developed develop VBD cord-006870-f5w6fw6q 5630 13 transient transient JJ cord-006870-f5w6fw6q 5630 14 reversible reversible JJ cord-006870-f5w6fw6q 5630 15 cerebral cerebral JJ cord-006870-f5w6fw6q 5630 16 edema edema NN cord-006870-f5w6fw6q 5630 17 believed believe VBD cord-006870-f5w6fw6q 5630 18 secondary secondary JJ cord-006870-f5w6fw6q 5630 19 to to IN cord-006870-f5w6fw6q 5630 20 aggressive aggressive JJ cord-006870-f5w6fw6q 5630 21 resuscitative resuscitative JJ cord-006870-f5w6fw6q 5630 22 efforts effort NNS cord-006870-f5w6fw6q 5630 23 and and CC cord-006870-f5w6fw6q 5630 24 pressor pressor NN cord-006870-f5w6fw6q 5630 25 therapies therapy NNS cord-006870-f5w6fw6q 5630 26 . . . cord-006870-f5w6fw6q 5631 1 A a DT cord-006870-f5w6fw6q 5631 2 55 55 CD cord-006870-f5w6fw6q 5631 3 year year NN cord-006870-f5w6fw6q 5631 4 old old JJ cord-006870-f5w6fw6q 5631 5 female female NN cord-006870-f5w6fw6q 5631 6 with with IN cord-006870-f5w6fw6q 5631 7 a a DT cord-006870-f5w6fw6q 5631 8 past past JJ cord-006870-f5w6fw6q 5631 9 medical medical JJ cord-006870-f5w6fw6q 5631 10 history history NN cord-006870-f5w6fw6q 5631 11 significant significant JJ cord-006870-f5w6fw6q 5631 12 for for IN cord-006870-f5w6fw6q 5631 13 diabetes diabetes NN cord-006870-f5w6fw6q 5631 14 and and CC cord-006870-f5w6fw6q 5631 15 hypertension hypertension NN cord-006870-f5w6fw6q 5631 16 presented present VBN cord-006870-f5w6fw6q 5631 17 to to IN cord-006870-f5w6fw6q 5631 18 the the DT cord-006870-f5w6fw6q 5631 19 emergency emergency NN cord-006870-f5w6fw6q 5631 20 department department NN cord-006870-f5w6fw6q 5631 21 with with IN cord-006870-f5w6fw6q 5631 22 headache headache NN cord-006870-f5w6fw6q 5631 23 and and CC cord-006870-f5w6fw6q 5631 24 non non JJ cord-006870-f5w6fw6q 5631 25 - - JJ cord-006870-f5w6fw6q 5631 26 bilious bilious JJ cord-006870-f5w6fw6q 5631 27 vomiting vomiting NN cord-006870-f5w6fw6q 5631 28 . . . cord-006870-f5w6fw6q 5632 1 Workup Workup NNP cord-006870-f5w6fw6q 5632 2 revealed reveal VBD cord-006870-f5w6fw6q 5632 3 isolated isolate VBN cord-006870-f5w6fw6q 5632 4 ventricular ventricular JJ cord-006870-f5w6fw6q 5632 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5632 6 secondary secondary JJ cord-006870-f5w6fw6q 5632 7 to to IN cord-006870-f5w6fw6q 5632 8 a a DT cord-006870-f5w6fw6q 5632 9 ruptured ruptured JJ cord-006870-f5w6fw6q 5632 10 left leave VBN cord-006870-f5w6fw6q 5632 11 Posterior Posterior NNP cord-006870-f5w6fw6q 5632 12 Inferior Inferior NNP cord-006870-f5w6fw6q 5632 13 Cerebellar Cerebellar NNP cord-006870-f5w6fw6q 5632 14 Artery Artery NNP cord-006870-f5w6fw6q 5632 15 ( ( -LRB- cord-006870-f5w6fw6q 5632 16 PICA pica NN cord-006870-f5w6fw6q 5632 17 ) ) -RRB- cord-006870-f5w6fw6q 5632 18 aneurysm aneurysm NN cord-006870-f5w6fw6q 5632 19 and and CC cord-006870-f5w6fw6q 5632 20 cerebellar cerebellar JJ cord-006870-f5w6fw6q 5632 21 arteriovenous arteriovenous JJ cord-006870-f5w6fw6q 5632 22 malformation malformation NN cord-006870-f5w6fw6q 5632 23 , , , cord-006870-f5w6fw6q 5632 24 which which WDT cord-006870-f5w6fw6q 5632 25 underwent undergo VBD cord-006870-f5w6fw6q 5632 26 subsequent subsequent JJ cord-006870-f5w6fw6q 5632 27 embolization embolization NN cord-006870-f5w6fw6q 5632 28 . . . cord-006870-f5w6fw6q 5633 1 During during IN cord-006870-f5w6fw6q 5633 2 her -PRON- PRP$ cord-006870-f5w6fw6q 5633 3 early early JJ cord-006870-f5w6fw6q 5633 4 hospital hospital NN cord-006870-f5w6fw6q 5633 5 course course NN cord-006870-f5w6fw6q 5633 6 she -PRON- PRP cord-006870-f5w6fw6q 5633 7 remained remain VBD cord-006870-f5w6fw6q 5633 8 intubated intubate VBN cord-006870-f5w6fw6q 5633 9 due due IN cord-006870-f5w6fw6q 5633 10 to to IN cord-006870-f5w6fw6q 5633 11 pulmonary pulmonary JJ cord-006870-f5w6fw6q 5633 12 factors factor NNS cord-006870-f5w6fw6q 5633 13 , , , cord-006870-f5w6fw6q 5633 14 but but CC cord-006870-f5w6fw6q 5633 15 awake awake JJ cord-006870-f5w6fw6q 5633 16 and and CC cord-006870-f5w6fw6q 5633 17 alert alert JJ cord-006870-f5w6fw6q 5633 18 with with IN cord-006870-f5w6fw6q 5633 19 a a DT cord-006870-f5w6fw6q 5633 20 non non JJ cord-006870-f5w6fw6q 5633 21 - - JJ cord-006870-f5w6fw6q 5633 22 focal focal JJ cord-006870-f5w6fw6q 5633 23 neurologic neurologic JJ cord-006870-f5w6fw6q 5633 24 examination examination NN cord-006870-f5w6fw6q 5633 25 . . . cord-006870-f5w6fw6q 5634 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 5634 2 course course NN cord-006870-f5w6fw6q 5634 3 was be VBD cord-006870-f5w6fw6q 5634 4 subsequently subsequently RB cord-006870-f5w6fw6q 5634 5 complicated complicate VBN cord-006870-f5w6fw6q 5634 6 by by IN cord-006870-f5w6fw6q 5634 7 a a DT cord-006870-f5w6fw6q 5634 8 severe severe JJ cord-006870-f5w6fw6q 5634 9 metabolic metabolic JJ cord-006870-f5w6fw6q 5634 10 acidosis acidosis NN cord-006870-f5w6fw6q 5634 11 requiring require VBG cord-006870-f5w6fw6q 5634 12 several several JJ cord-006870-f5w6fw6q 5634 13 doses dose NNS cord-006870-f5w6fw6q 5634 14 of of IN cord-006870-f5w6fw6q 5634 15 bicarbonate bicarbonate NN cord-006870-f5w6fw6q 5634 16 boluses bolus NNS cord-006870-f5w6fw6q 5634 17 and and CC cord-006870-f5w6fw6q 5634 18 continuous continuous JJ cord-006870-f5w6fw6q 5634 19 infusion infusion NN cord-006870-f5w6fw6q 5634 20 , , , cord-006870-f5w6fw6q 5634 21 CVVHD CVVHD NNP cord-006870-f5w6fw6q 5634 22 , , , cord-006870-f5w6fw6q 5634 23 intravenous intravenous JJ cord-006870-f5w6fw6q 5634 24 crystalloids crystalloid NNS cord-006870-f5w6fw6q 5634 25 , , , cord-006870-f5w6fw6q 5634 26 hydrocortisone hydrocortisone NN cord-006870-f5w6fw6q 5634 27 and and CC cord-006870-f5w6fw6q 5634 28 multiple multiple JJ cord-006870-f5w6fw6q 5634 29 pressors pressor NNS cord-006870-f5w6fw6q 5634 30 to to TO cord-006870-f5w6fw6q 5634 31 maintain maintain VB cord-006870-f5w6fw6q 5634 32 stability stability NN cord-006870-f5w6fw6q 5634 33 . . . cord-006870-f5w6fw6q 5635 1 Over over IN cord-006870-f5w6fw6q 5635 2 a a DT cord-006870-f5w6fw6q 5635 3 24 24 CD cord-006870-f5w6fw6q 5635 4 hour hour NN cord-006870-f5w6fw6q 5635 5 period period NN cord-006870-f5w6fw6q 5635 6 she -PRON- PRP cord-006870-f5w6fw6q 5635 7 received receive VBD cord-006870-f5w6fw6q 5635 8 10 10 CD cord-006870-f5w6fw6q 5635 9 liters liter NNS cord-006870-f5w6fw6q 5635 10 of of IN cord-006870-f5w6fw6q 5635 11 volume volume NN cord-006870-f5w6fw6q 5635 12 while while IN cord-006870-f5w6fw6q 5635 13 maintaining maintain VBG cord-006870-f5w6fw6q 5635 14 a a DT cord-006870-f5w6fw6q 5635 15 mean mean JJ cord-006870-f5w6fw6q 5635 16 arterial arterial JJ cord-006870-f5w6fw6q 5635 17 pressure pressure NN cord-006870-f5w6fw6q 5635 18 above above IN cord-006870-f5w6fw6q 5635 19 60 60 CD cord-006870-f5w6fw6q 5635 20 mm mm NN cord-006870-f5w6fw6q 5635 21 Hg Hg NNP cord-006870-f5w6fw6q 5635 22 and and CC cord-006870-f5w6fw6q 5635 23 O2 o2 NN cord-006870-f5w6fw6q 5635 24 saturations saturation NNS cord-006870-f5w6fw6q 5635 25 above above IN cord-006870-f5w6fw6q 5635 26 88 88 CD cord-006870-f5w6fw6q 5635 27 % % NN cord-006870-f5w6fw6q 5635 28 , , , cord-006870-f5w6fw6q 5635 29 without without IN cord-006870-f5w6fw6q 5635 30 requiring require VBG cord-006870-f5w6fw6q 5635 31 CPR CPR NNP cord-006870-f5w6fw6q 5635 32 . . . cord-006870-f5w6fw6q 5636 1 Subsequent subsequent JJ cord-006870-f5w6fw6q 5636 2 progressive progressive JJ cord-006870-f5w6fw6q 5636 3 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5636 4 developed develop VBN cord-006870-f5w6fw6q 5636 5 , , , cord-006870-f5w6fw6q 5636 6 with with IN cord-006870-f5w6fw6q 5636 7 a a DT cord-006870-f5w6fw6q 5636 8 CT CT NNP cord-006870-f5w6fw6q 5636 9 Brain Brain NNP cord-006870-f5w6fw6q 5636 10 revealing reveal VBG cord-006870-f5w6fw6q 5636 11 diffuse diffuse JJ cord-006870-f5w6fw6q 5636 12 sulcal sulcal JJ cord-006870-f5w6fw6q 5636 13 effacement effacement NN cord-006870-f5w6fw6q 5636 14 prompting prompt VBG cord-006870-f5w6fw6q 5636 15 hyperosmolar hyperosmolar NNP cord-006870-f5w6fw6q 5636 16 therapy therapy NN cord-006870-f5w6fw6q 5636 17 . . . cord-006870-f5w6fw6q 5637 1 Gradually gradually RB cord-006870-f5w6fw6q 5637 2 her -PRON- PRP$ cord-006870-f5w6fw6q 5637 3 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5637 4 began begin VBD cord-006870-f5w6fw6q 5637 5 to to TO cord-006870-f5w6fw6q 5637 6 improve improve VB cord-006870-f5w6fw6q 5637 7 , , , cord-006870-f5w6fw6q 5637 8 with with IN cord-006870-f5w6fw6q 5637 9 repeat repeat NN cord-006870-f5w6fw6q 5637 10 imaging image VBG cord-006870-f5w6fw6q 5637 11 showing show VBG cord-006870-f5w6fw6q 5637 12 improvement improvement NN cord-006870-f5w6fw6q 5637 13 of of IN cord-006870-f5w6fw6q 5637 14 cerebral cerebral JJ cord-006870-f5w6fw6q 5637 15 edema edema NN cord-006870-f5w6fw6q 5637 16 and and CC cord-006870-f5w6fw6q 5637 17 return return NN cord-006870-f5w6fw6q 5637 18 of of IN cord-006870-f5w6fw6q 5637 19 grey grey JJ cord-006870-f5w6fw6q 5637 20 / / SYM cord-006870-f5w6fw6q 5637 21 white white JJ cord-006870-f5w6fw6q 5637 22 matter matter NN cord-006870-f5w6fw6q 5637 23 differentiation differentiation NN cord-006870-f5w6fw6q 5637 24 . . . cord-006870-f5w6fw6q 5638 1 This this DT cord-006870-f5w6fw6q 5638 2 case case NN cord-006870-f5w6fw6q 5638 3 highlights highlight VBZ cord-006870-f5w6fw6q 5638 4 a a DT cord-006870-f5w6fw6q 5638 5 potential potential JJ cord-006870-f5w6fw6q 5638 6 etiology etiology NN cord-006870-f5w6fw6q 5638 7 of of IN cord-006870-f5w6fw6q 5638 8 reversible reversible JJ cord-006870-f5w6fw6q 5638 9 cerebral cerebral JJ cord-006870-f5w6fw6q 5638 10 edema edema NN cord-006870-f5w6fw6q 5638 11 that that WDT cord-006870-f5w6fw6q 5638 12 may may MD cord-006870-f5w6fw6q 5638 13 confound confound VB cord-006870-f5w6fw6q 5638 14 early early JJ cord-006870-f5w6fw6q 5638 15 prognostication prognostication NN cord-006870-f5w6fw6q 5638 16 in in IN cord-006870-f5w6fw6q 5638 17 patients patient NNS cord-006870-f5w6fw6q 5638 18 with with IN cord-006870-f5w6fw6q 5638 19 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 5638 20 instability instability NN cord-006870-f5w6fw6q 5638 21 such such JJ cord-006870-f5w6fw6q 5638 22 as as IN cord-006870-f5w6fw6q 5638 23 multi multi JJ cord-006870-f5w6fw6q 5638 24 - - JJ cord-006870-f5w6fw6q 5638 25 organ organ JJ cord-006870-f5w6fw6q 5638 26 failure failure NN cord-006870-f5w6fw6q 5638 27 and and CC cord-006870-f5w6fw6q 5638 28 in in IN cord-006870-f5w6fw6q 5638 29 - - HYPH cord-006870-f5w6fw6q 5638 30 hospital hospital NN cord-006870-f5w6fw6q 5638 31 cardiac cardiac JJ cord-006870-f5w6fw6q 5638 32 arrest arrest NN cord-006870-f5w6fw6q 5638 33 . . . cord-006870-f5w6fw6q 5639 1 Further further JJ cord-006870-f5w6fw6q 5639 2 investigations investigation NNS cord-006870-f5w6fw6q 5639 3 are be VBP cord-006870-f5w6fw6q 5639 4 warranted warrant VBN cord-006870-f5w6fw6q 5639 5 . . . cord-006870-f5w6fw6q 5640 1 Langerhans Langerhans NNP cord-006870-f5w6fw6q 5640 2 cell cell NN cord-006870-f5w6fw6q 5640 3 histiocytosis histiocytosis NN cord-006870-f5w6fw6q 5640 4 ( ( -LRB- cord-006870-f5w6fw6q 5640 5 LCH LCH NNP cord-006870-f5w6fw6q 5640 6 ) ) -RRB- cord-006870-f5w6fw6q 5640 7 is be VBZ cord-006870-f5w6fw6q 5640 8 a a DT cord-006870-f5w6fw6q 5640 9 rare rare JJ cord-006870-f5w6fw6q 5640 10 disease disease NN cord-006870-f5w6fw6q 5640 11 with with IN cord-006870-f5w6fw6q 5640 12 an an DT cord-006870-f5w6fw6q 5640 13 incidence incidence NN cord-006870-f5w6fw6q 5640 14 of of IN cord-006870-f5w6fw6q 5640 15 0.2 0.2 CD cord-006870-f5w6fw6q 5640 16 - - SYM cord-006870-f5w6fw6q 5640 17 2.0 2.0 CD cord-006870-f5w6fw6q 5640 18 cases case NNS cord-006870-f5w6fw6q 5640 19 per per IN cord-006870-f5w6fw6q 5640 20 1000,000 1000,000 CD cord-006870-f5w6fw6q 5640 21 children child NNS cord-006870-f5w6fw6q 5640 22 under under IN cord-006870-f5w6fw6q 5640 23 15 15 CD cord-006870-f5w6fw6q 5640 24 years year NNS cord-006870-f5w6fw6q 5640 25 of of IN cord-006870-f5w6fw6q 5640 26 age age NN cord-006870-f5w6fw6q 5640 27 . . . cord-006870-f5w6fw6q 5641 1 Frequency frequency NN cord-006870-f5w6fw6q 5641 2 in in IN cord-006870-f5w6fw6q 5641 3 adults adult NNS cord-006870-f5w6fw6q 5641 4 is be VBZ cord-006870-f5w6fw6q 5641 5 unknown unknown JJ cord-006870-f5w6fw6q 5641 6 . . . cord-006870-f5w6fw6q 5642 1 The the DT cord-006870-f5w6fw6q 5642 2 hypothalamic hypothalamic JJ cord-006870-f5w6fw6q 5642 3 - - HYPH cord-006870-f5w6fw6q 5642 4 pituitary pituitary JJ cord-006870-f5w6fw6q 5642 5 manifestations manifestation NNS cord-006870-f5w6fw6q 5642 6 of of IN cord-006870-f5w6fw6q 5642 7 LCH LCH NNP cord-006870-f5w6fw6q 5642 8 ( ( -LRB- cord-006870-f5w6fw6q 5642 9 commonly commonly RB cord-006870-f5w6fw6q 5642 10 diabetes diabetes NN cord-006870-f5w6fw6q 5642 11 insipidus insipidus NN cord-006870-f5w6fw6q 5642 12 ) ) -RRB- cord-006870-f5w6fw6q 5642 13 and and CC cord-006870-f5w6fw6q 5642 14 hypernatremia hypernatremia NN cord-006870-f5w6fw6q 5642 15 are be VBP cord-006870-f5w6fw6q 5642 16 well well RB cord-006870-f5w6fw6q 5642 17 known know VBN cord-006870-f5w6fw6q 5642 18 complications complication NNS cord-006870-f5w6fw6q 5642 19 . . . cord-006870-f5w6fw6q 5643 1 Here here RB cord-006870-f5w6fw6q 5643 2 we -PRON- PRP cord-006870-f5w6fw6q 5643 3 present present VBP cord-006870-f5w6fw6q 5643 4 a a DT cord-006870-f5w6fw6q 5643 5 case case NN cord-006870-f5w6fw6q 5643 6 where where WRB cord-006870-f5w6fw6q 5643 7 a a DT cord-006870-f5w6fw6q 5643 8 patient patient NN cord-006870-f5w6fw6q 5643 9 presented present VBN cord-006870-f5w6fw6q 5643 10 with with IN cord-006870-f5w6fw6q 5643 11 poor poor JJ cord-006870-f5w6fw6q 5643 12 mental mental JJ cord-006870-f5w6fw6q 5643 13 status status NN cord-006870-f5w6fw6q 5643 14 and and CC cord-006870-f5w6fw6q 5643 15 the the DT cord-006870-f5w6fw6q 5643 16 etiology etiology NN cord-006870-f5w6fw6q 5643 17 remained remain VBD cord-006870-f5w6fw6q 5643 18 unknown unknown JJ cord-006870-f5w6fw6q 5643 19 initially initially RB cord-006870-f5w6fw6q 5643 20 despite despite IN cord-006870-f5w6fw6q 5643 21 extensive extensive JJ cord-006870-f5w6fw6q 5643 22 testing testing NN cord-006870-f5w6fw6q 5643 23 . . . cord-006870-f5w6fw6q 5644 1 Electronic electronic JJ cord-006870-f5w6fw6q 5644 2 medical medical JJ cord-006870-f5w6fw6q 5644 3 record record NN cord-006870-f5w6fw6q 5644 4 was be VBD cord-006870-f5w6fw6q 5644 5 reviewed review VBN cord-006870-f5w6fw6q 5644 6 regarding regard VBG cord-006870-f5w6fw6q 5644 7 hospital hospital NN cord-006870-f5w6fw6q 5644 8 course course NN cord-006870-f5w6fw6q 5644 9 , , , cord-006870-f5w6fw6q 5644 10 sodium sodium NN cord-006870-f5w6fw6q 5644 11 trends trend NNS cord-006870-f5w6fw6q 5644 12 , , , cord-006870-f5w6fw6q 5644 13 and and CC cord-006870-f5w6fw6q 5644 14 radiology radiology NN cord-006870-f5w6fw6q 5644 15 images image NNS cord-006870-f5w6fw6q 5644 16 . . . cord-006870-f5w6fw6q 5645 1 This this DT cord-006870-f5w6fw6q 5645 2 patient patient NN cord-006870-f5w6fw6q 5645 3 is be VBZ cord-006870-f5w6fw6q 5645 4 a a DT cord-006870-f5w6fw6q 5645 5 66 66 CD cord-006870-f5w6fw6q 5645 6 year year NN cord-006870-f5w6fw6q 5645 7 old old JJ cord-006870-f5w6fw6q 5645 8 female female NN cord-006870-f5w6fw6q 5645 9 with with IN cord-006870-f5w6fw6q 5645 10 history history NN cord-006870-f5w6fw6q 5645 11 of of IN cord-006870-f5w6fw6q 5645 12 Langerhans Langerhans NNP cord-006870-f5w6fw6q 5645 13 ' ' POS cord-006870-f5w6fw6q 5645 14 cell cell NN cord-006870-f5w6fw6q 5645 15 histiocytosis histiocytosis NN cord-006870-f5w6fw6q 5645 16 with with IN cord-006870-f5w6fw6q 5645 17 biopsy biopsy NN cord-006870-f5w6fw6q 5645 18 - - HYPH cord-006870-f5w6fw6q 5645 19 confirmed confirm VBN cord-006870-f5w6fw6q 5645 20 suprasellar suprasellar JJ cord-006870-f5w6fw6q 5645 21 metastases metastasis NNS cord-006870-f5w6fw6q 5645 22 ( ( -LRB- cord-006870-f5w6fw6q 5645 23 complicated complicate VBN cord-006870-f5w6fw6q 5645 24 by by IN cord-006870-f5w6fw6q 5645 25 pan pan NN cord-006870-f5w6fw6q 5645 26 - - JJ cord-006870-f5w6fw6q 5645 27 hypopituitarism hypopituitarism NN cord-006870-f5w6fw6q 5645 28 ) ) -RRB- cord-006870-f5w6fw6q 5645 29 who who WP cord-006870-f5w6fw6q 5645 30 was be VBD cord-006870-f5w6fw6q 5645 31 transferred transfer VBN cord-006870-f5w6fw6q 5645 32 to to IN cord-006870-f5w6fw6q 5645 33 our -PRON- PRP$ cord-006870-f5w6fw6q 5645 34 institution institution NN cord-006870-f5w6fw6q 5645 35 for for IN cord-006870-f5w6fw6q 5645 36 hypernatremia hypernatremia NN cord-006870-f5w6fw6q 5645 37 and and CC cord-006870-f5w6fw6q 5645 38 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5645 39 . . . cord-006870-f5w6fw6q 5646 1 She -PRON- PRP cord-006870-f5w6fw6q 5646 2 had have VBD cord-006870-f5w6fw6q 5646 3 undergone undergo VBN cord-006870-f5w6fw6q 5646 4 two two CD cord-006870-f5w6fw6q 5646 5 cycles cycle NNS cord-006870-f5w6fw6q 5646 6 of of IN cord-006870-f5w6fw6q 5646 7 chemotherapy chemotherapy NN cord-006870-f5w6fw6q 5646 8 , , , cord-006870-f5w6fw6q 5646 9 most most RBS cord-006870-f5w6fw6q 5646 10 recently recently RB cord-006870-f5w6fw6q 5646 11 one one CD cord-006870-f5w6fw6q 5646 12 week week NN cord-006870-f5w6fw6q 5646 13 prior prior RB cord-006870-f5w6fw6q 5646 14 to to IN cord-006870-f5w6fw6q 5646 15 presentation presentation NN cord-006870-f5w6fw6q 5646 16 , , , cord-006870-f5w6fw6q 5646 17 and and CC cord-006870-f5w6fw6q 5646 18 five five CD cord-006870-f5w6fw6q 5646 19 rounds round NNS cord-006870-f5w6fw6q 5646 20 of of IN cord-006870-f5w6fw6q 5646 21 radiation radiation NN cord-006870-f5w6fw6q 5646 22 completed complete VBD cord-006870-f5w6fw6q 5646 23 three three CD cord-006870-f5w6fw6q 5646 24 months month NNS cord-006870-f5w6fw6q 5646 25 earlier early RBR cord-006870-f5w6fw6q 5646 26 . . . cord-006870-f5w6fw6q 5647 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 5647 2 presentation presentation NN cord-006870-f5w6fw6q 5647 3 to to IN cord-006870-f5w6fw6q 5647 4 the the DT cord-006870-f5w6fw6q 5647 5 community community NN cord-006870-f5w6fw6q 5647 6 hospital hospital NN cord-006870-f5w6fw6q 5647 7 from from IN cord-006870-f5w6fw6q 5647 8 a a DT cord-006870-f5w6fw6q 5647 9 nursing nursing NN cord-006870-f5w6fw6q 5647 10 facility facility NN cord-006870-f5w6fw6q 5647 11 was be VBD cord-006870-f5w6fw6q 5647 12 with with IN cord-006870-f5w6fw6q 5647 13 unresponsiveness unresponsiveness NN cord-006870-f5w6fw6q 5647 14 and and CC cord-006870-f5w6fw6q 5647 15 she -PRON- PRP cord-006870-f5w6fw6q 5647 16 was be VBD cord-006870-f5w6fw6q 5647 17 intubated intubate VBN cord-006870-f5w6fw6q 5647 18 on on IN cord-006870-f5w6fw6q 5647 19 arrival arrival NN cord-006870-f5w6fw6q 5647 20 . . . cord-006870-f5w6fw6q 5648 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 5648 2 sodium sodium NN cord-006870-f5w6fw6q 5648 3 was be VBD cord-006870-f5w6fw6q 5648 4 174 174 CD cord-006870-f5w6fw6q 5648 5 at at IN cord-006870-f5w6fw6q 5648 6 that that DT cord-006870-f5w6fw6q 5648 7 time time NN cord-006870-f5w6fw6q 5648 8 ; ; : cord-006870-f5w6fw6q 5648 9 and and CC cord-006870-f5w6fw6q 5648 10 had have VBD cord-006870-f5w6fw6q 5648 11 been be VBN cord-006870-f5w6fw6q 5648 12 137 137 CD cord-006870-f5w6fw6q 5648 13 three three CD cord-006870-f5w6fw6q 5648 14 days day NNS cord-006870-f5w6fw6q 5648 15 prior prior RB cord-006870-f5w6fw6q 5648 16 . . . cord-006870-f5w6fw6q 5649 1 Sodium sodium NN cord-006870-f5w6fw6q 5649 2 was be VBD cord-006870-f5w6fw6q 5649 3 corrected correct VBN cord-006870-f5w6fw6q 5649 4 from from IN cord-006870-f5w6fw6q 5649 5 174 174 CD cord-006870-f5w6fw6q 5649 6 to to IN cord-006870-f5w6fw6q 5649 7 139 139 CD cord-006870-f5w6fw6q 5649 8 over over IN cord-006870-f5w6fw6q 5649 9 the the DT cord-006870-f5w6fw6q 5649 10 course course NN cord-006870-f5w6fw6q 5649 11 of of IN cord-006870-f5w6fw6q 5649 12 four four CD cord-006870-f5w6fw6q 5649 13 days day NNS cord-006870-f5w6fw6q 5649 14 with with IN cord-006870-f5w6fw6q 5649 15 a a DT cord-006870-f5w6fw6q 5649 16 drop drop NN cord-006870-f5w6fw6q 5649 17 from from IN cord-006870-f5w6fw6q 5649 18 174 174 CD cord-006870-f5w6fw6q 5649 19 to to IN cord-006870-f5w6fw6q 5649 20 157 157 CD cord-006870-f5w6fw6q 5649 21 within within IN cord-006870-f5w6fw6q 5649 22 the the DT cord-006870-f5w6fw6q 5649 23 first first JJ cord-006870-f5w6fw6q 5649 24 ten ten CD cord-006870-f5w6fw6q 5649 25 hours hour NNS cord-006870-f5w6fw6q 5649 26 . . . cord-006870-f5w6fw6q 5650 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 5650 2 mental mental JJ cord-006870-f5w6fw6q 5650 3 status status NN cord-006870-f5w6fw6q 5650 4 improved improve VBN cord-006870-f5w6fw6q 5650 5 to to IN cord-006870-f5w6fw6q 5650 6 the the DT cord-006870-f5w6fw6q 5650 7 point point NN cord-006870-f5w6fw6q 5650 8 where where WRB cord-006870-f5w6fw6q 5650 9 she -PRON- PRP cord-006870-f5w6fw6q 5650 10 was be VBD cord-006870-f5w6fw6q 5650 11 awake awake JJ cord-006870-f5w6fw6q 5650 12 and and CC cord-006870-f5w6fw6q 5650 13 following follow VBG cord-006870-f5w6fw6q 5650 14 commands command NNS cord-006870-f5w6fw6q 5650 15 ; ; : cord-006870-f5w6fw6q 5650 16 however however RB cord-006870-f5w6fw6q 5650 17 still still RB cord-006870-f5w6fw6q 5650 18 remained remain VBD cord-006870-f5w6fw6q 5650 19 intubated intubate VBN cord-006870-f5w6fw6q 5650 20 . . . cord-006870-f5w6fw6q 5651 1 When when WRB cord-006870-f5w6fw6q 5651 2 she -PRON- PRP cord-006870-f5w6fw6q 5651 3 presented present VBD cord-006870-f5w6fw6q 5651 4 to to IN cord-006870-f5w6fw6q 5651 5 our -PRON- PRP$ cord-006870-f5w6fw6q 5651 6 institution institution NN cord-006870-f5w6fw6q 5651 7 her -PRON- PRP$ cord-006870-f5w6fw6q 5651 8 sodium sodium NN cord-006870-f5w6fw6q 5651 9 was be VBD cord-006870-f5w6fw6q 5651 10 139 139 CD cord-006870-f5w6fw6q 5651 11 and and CC cord-006870-f5w6fw6q 5651 12 subsequently subsequently RB cord-006870-f5w6fw6q 5651 13 became become VBD cord-006870-f5w6fw6q 5651 14 unresponsive unresponsive JJ cord-006870-f5w6fw6q 5651 15 with with IN cord-006870-f5w6fw6q 5651 16 a a DT cord-006870-f5w6fw6q 5651 17 poor poor JJ cord-006870-f5w6fw6q 5651 18 neurological neurological JJ cord-006870-f5w6fw6q 5651 19 exam exam NN cord-006870-f5w6fw6q 5651 20 limited limit VBN cord-006870-f5w6fw6q 5651 21 to to IN cord-006870-f5w6fw6q 5651 22 cranial cranial JJ cord-006870-f5w6fw6q 5651 23 nerve nerve NN cord-006870-f5w6fw6q 5651 24 function function NN cord-006870-f5w6fw6q 5651 25 only only RB cord-006870-f5w6fw6q 5651 26 . . . cord-006870-f5w6fw6q 5652 1 She -PRON- PRP cord-006870-f5w6fw6q 5652 2 was be VBD cord-006870-f5w6fw6q 5652 3 evaluated evaluate VBN cord-006870-f5w6fw6q 5652 4 with with IN cord-006870-f5w6fw6q 5652 5 EEG EEG NNP cord-006870-f5w6fw6q 5652 6 monitoring monitoring NN cord-006870-f5w6fw6q 5652 7 and and CC cord-006870-f5w6fw6q 5652 8 MRI MRI NNP cord-006870-f5w6fw6q 5652 9 brain brain NN cord-006870-f5w6fw6q 5652 10 ; ; : cord-006870-f5w6fw6q 5652 11 however however RB cord-006870-f5w6fw6q 5652 12 both both DT cord-006870-f5w6fw6q 5652 13 were be VBD cord-006870-f5w6fw6q 5652 14 unrevealing unrevealing JJ cord-006870-f5w6fw6q 5652 15 for for IN cord-006870-f5w6fw6q 5652 16 a a DT cord-006870-f5w6fw6q 5652 17 cause cause NN cord-006870-f5w6fw6q 5652 18 . . . cord-006870-f5w6fw6q 5653 1 She -PRON- PRP cord-006870-f5w6fw6q 5653 2 had have VBD cord-006870-f5w6fw6q 5653 3 an an DT cord-006870-f5w6fw6q 5653 4 external external JJ cord-006870-f5w6fw6q 5653 5 ventricular ventricular JJ cord-006870-f5w6fw6q 5653 6 drain drain NN cord-006870-f5w6fw6q 5653 7 placed place VBN cord-006870-f5w6fw6q 5653 8 for for IN cord-006870-f5w6fw6q 5653 9 concern concern NN cord-006870-f5w6fw6q 5653 10 for for IN cord-006870-f5w6fw6q 5653 11 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 5653 12 that that WDT cord-006870-f5w6fw6q 5653 13 did do VBD cord-006870-f5w6fw6q 5653 14 not not RB cord-006870-f5w6fw6q 5653 15 change change VB cord-006870-f5w6fw6q 5653 16 her -PRON- PRP$ cord-006870-f5w6fw6q 5653 17 exam exam NN cord-006870-f5w6fw6q 5653 18 . . . cord-006870-f5w6fw6q 5654 1 One one CD cord-006870-f5w6fw6q 5654 2 week week NN cord-006870-f5w6fw6q 5654 3 later later RB cord-006870-f5w6fw6q 5654 4 repeat repeat NN cord-006870-f5w6fw6q 5655 1 MRI MRI NNP cord-006870-f5w6fw6q 5655 2 brain brain NN cord-006870-f5w6fw6q 5655 3 revealed reveal VBD cord-006870-f5w6fw6q 5655 4 extrapontine extrapontine NNP cord-006870-f5w6fw6q 5655 5 myelinolysis myelinolysis NNP cord-006870-f5w6fw6q 5655 6 . . . cord-006870-f5w6fw6q 5656 1 This this DT cord-006870-f5w6fw6q 5656 2 case case NN cord-006870-f5w6fw6q 5656 3 highlights highlight VBZ cord-006870-f5w6fw6q 5656 4 the the DT cord-006870-f5w6fw6q 5656 5 complications complication NNS cord-006870-f5w6fw6q 5656 6 associated associate VBN cord-006870-f5w6fw6q 5656 7 with with IN cord-006870-f5w6fw6q 5656 8 intracranial intracranial JJ cord-006870-f5w6fw6q 5656 9 LCH LCH NNP cord-006870-f5w6fw6q 5656 10 and and CC cord-006870-f5w6fw6q 5656 11 the the DT cord-006870-f5w6fw6q 5656 12 need need NN cord-006870-f5w6fw6q 5656 13 for for IN cord-006870-f5w6fw6q 5656 14 repeat repeat NN cord-006870-f5w6fw6q 5656 15 imaging imaging NN cord-006870-f5w6fw6q 5656 16 in in IN cord-006870-f5w6fw6q 5656 17 patients patient NNS cord-006870-f5w6fw6q 5656 18 with with IN cord-006870-f5w6fw6q 5656 19 rapid rapid JJ cord-006870-f5w6fw6q 5656 20 sodium sodium NN cord-006870-f5w6fw6q 5656 21 correction correction NN cord-006870-f5w6fw6q 5656 22 to to TO cord-006870-f5w6fw6q 5656 23 identify identify VB cord-006870-f5w6fw6q 5656 24 effects effect NNS cord-006870-f5w6fw6q 5656 25 of of IN cord-006870-f5w6fw6q 5656 26 osmotic osmotic JJ cord-006870-f5w6fw6q 5656 27 demyelination demyelination NN cord-006870-f5w6fw6q 5656 28 . . . cord-006870-f5w6fw6q 5657 1 Cangrelor Cangrelor NNP cord-006870-f5w6fw6q 5657 2 is be VBZ cord-006870-f5w6fw6q 5657 3 a a DT cord-006870-f5w6fw6q 5657 4 rapid rapid JJ cord-006870-f5w6fw6q 5657 5 - - HYPH cord-006870-f5w6fw6q 5657 6 acting act VBG cord-006870-f5w6fw6q 5657 7 , , , cord-006870-f5w6fw6q 5657 8 intravenous intravenous JJ cord-006870-f5w6fw6q 5657 9 P2Y12 P2Y12 NNP cord-006870-f5w6fw6q 5657 10 platelet platelet NN cord-006870-f5w6fw6q 5657 11 receptor receptor NN cord-006870-f5w6fw6q 5657 12 inhibitor inhibitor NN cord-006870-f5w6fw6q 5657 13 with with IN cord-006870-f5w6fw6q 5657 14 a a DT cord-006870-f5w6fw6q 5657 15 plasma plasma NN cord-006870-f5w6fw6q 5657 16 half half JJ cord-006870-f5w6fw6q 5657 17 - - HYPH cord-006870-f5w6fw6q 5657 18 life life NN cord-006870-f5w6fw6q 5657 19 of of IN cord-006870-f5w6fw6q 5657 20 3 3 CD cord-006870-f5w6fw6q 5657 21 - - SYM cord-006870-f5w6fw6q 5657 22 6 6 CD cord-006870-f5w6fw6q 5657 23 minutes minute NNS cord-006870-f5w6fw6q 5657 24 and and CC cord-006870-f5w6fw6q 5657 25 full full JJ cord-006870-f5w6fw6q 5657 26 platelet platelet NN cord-006870-f5w6fw6q 5657 27 recovery recovery NN cord-006870-f5w6fw6q 5657 28 achieved achieve VBN cord-006870-f5w6fw6q 5657 29 within within IN cord-006870-f5w6fw6q 5657 30 one one CD cord-006870-f5w6fw6q 5657 31 hour hour NN cord-006870-f5w6fw6q 5657 32 after after IN cord-006870-f5w6fw6q 5657 33 discontinuation discontinuation NN cord-006870-f5w6fw6q 5657 34 . . . cord-006870-f5w6fw6q 5658 1 Because because IN cord-006870-f5w6fw6q 5658 2 it -PRON- PRP cord-006870-f5w6fw6q 5658 3 is be VBZ cord-006870-f5w6fw6q 5658 4 rapidly rapidly RB cord-006870-f5w6fw6q 5658 5 reversible reversible JJ cord-006870-f5w6fw6q 5658 6 , , , cord-006870-f5w6fw6q 5658 7 cangrelor cangrelor NN cord-006870-f5w6fw6q 5658 8 is be VBZ cord-006870-f5w6fw6q 5658 9 commonly commonly RB cord-006870-f5w6fw6q 5658 10 used use VBN cord-006870-f5w6fw6q 5658 11 to to TO cord-006870-f5w6fw6q 5658 12 bridge bridge VB cord-006870-f5w6fw6q 5658 13 patients patient NNS cord-006870-f5w6fw6q 5658 14 with with IN cord-006870-f5w6fw6q 5658 15 recent recent JJ cord-006870-f5w6fw6q 5658 16 coronary coronary JJ cord-006870-f5w6fw6q 5658 17 stents stent NNS cord-006870-f5w6fw6q 5658 18 to to IN cord-006870-f5w6fw6q 5658 19 CABG CABG NNP cord-006870-f5w6fw6q 5658 20 surgery surgery NN cord-006870-f5w6fw6q 5658 21 . . . cord-006870-f5w6fw6q 5659 1 Oral oral JJ cord-006870-f5w6fw6q 5659 2 P2Y12 P2Y12 NNP cord-006870-f5w6fw6q 5659 3 inhibitors inhibitor NNS cord-006870-f5w6fw6q 5659 4 , , , cord-006870-f5w6fw6q 5659 5 such such JJ cord-006870-f5w6fw6q 5659 6 as as IN cord-006870-f5w6fw6q 5659 7 clopidogrel clopidogrel NNP cord-006870-f5w6fw6q 5659 8 , , , cord-006870-f5w6fw6q 5659 9 have have VBP cord-006870-f5w6fw6q 5659 10 a a DT cord-006870-f5w6fw6q 5659 11 delayed delay VBN cord-006870-f5w6fw6q 5659 12 onset onset NN cord-006870-f5w6fw6q 5659 13 and and CC cord-006870-f5w6fw6q 5659 14 offset offset VBN cord-006870-f5w6fw6q 5659 15 with with IN cord-006870-f5w6fw6q 5659 16 platelet platelet NN cord-006870-f5w6fw6q 5659 17 recovery recovery NN cord-006870-f5w6fw6q 5659 18 occurring occur VBG cord-006870-f5w6fw6q 5659 19 over over IN cord-006870-f5w6fw6q 5659 20 5 5 CD cord-006870-f5w6fw6q 5659 21 - - SYM cord-006870-f5w6fw6q 5659 22 7 7 CD cord-006870-f5w6fw6q 5659 23 days day NNS cord-006870-f5w6fw6q 5659 24 , , , cord-006870-f5w6fw6q 5659 25 making make VBG cord-006870-f5w6fw6q 5659 26 their -PRON- PRP$ cord-006870-f5w6fw6q 5659 27 use use VB cord-006870-f5w6fw6q 5659 28 challenging challenging JJ cord-006870-f5w6fw6q 5659 29 perioperatively perioperatively NN cord-006870-f5w6fw6q 5659 30 or or CC cord-006870-f5w6fw6q 5659 31 in in IN cord-006870-f5w6fw6q 5659 32 the the DT cord-006870-f5w6fw6q 5659 33 setting setting NN cord-006870-f5w6fw6q 5659 34 of of IN cord-006870-f5w6fw6q 5659 35 an an DT cord-006870-f5w6fw6q 5659 36 acute acute JJ cord-006870-f5w6fw6q 5659 37 bleed bleed NN cord-006870-f5w6fw6q 5659 38 . . . cord-006870-f5w6fw6q 5660 1 Safety safety NN cord-006870-f5w6fw6q 5660 2 and and CC cord-006870-f5w6fw6q 5660 3 efficacy efficacy NN cord-006870-f5w6fw6q 5660 4 data datum NNS cord-006870-f5w6fw6q 5660 5 of of IN cord-006870-f5w6fw6q 5660 6 cangrelor cangrelor NNP cord-006870-f5w6fw6q 5660 7 in in IN cord-006870-f5w6fw6q 5660 8 noncoronary noncoronary NNP cord-006870-f5w6fw6q 5660 9 stents stent NNS cord-006870-f5w6fw6q 5660 10 are be VBP cord-006870-f5w6fw6q 5660 11 lacking lack VBG cord-006870-f5w6fw6q 5660 12 . . . cord-006870-f5w6fw6q 5661 1 We -PRON- PRP cord-006870-f5w6fw6q 5661 2 present present VBP cord-006870-f5w6fw6q 5661 3 two two CD cord-006870-f5w6fw6q 5661 4 patients patient NNS cord-006870-f5w6fw6q 5661 5 in in IN cord-006870-f5w6fw6q 5661 6 whom whom WP cord-006870-f5w6fw6q 5661 7 cangrelor cangrelor NNP cord-006870-f5w6fw6q 5661 8 was be VBD cord-006870-f5w6fw6q 5661 9 used use VBN cord-006870-f5w6fw6q 5661 10 to to TO cord-006870-f5w6fw6q 5661 11 maintain maintain VB cord-006870-f5w6fw6q 5661 12 internal internal JJ cord-006870-f5w6fw6q 5661 13 carotid carotid JJ cord-006870-f5w6fw6q 5661 14 artery artery NN cord-006870-f5w6fw6q 5661 15 ( ( -LRB- cord-006870-f5w6fw6q 5661 16 ICA ICA NNP cord-006870-f5w6fw6q 5661 17 ) ) -RRB- cord-006870-f5w6fw6q 5661 18 stent stent NNP cord-006870-f5w6fw6q 5661 19 patency patency NNP cord-006870-f5w6fw6q 5661 20 acutely acutely RB cord-006870-f5w6fw6q 5661 21 . . . cord-006870-f5w6fw6q 5662 1 Both both DT cord-006870-f5w6fw6q 5662 2 patients patient NNS cord-006870-f5w6fw6q 5662 3 presented present VBN cord-006870-f5w6fw6q 5662 4 with with IN cord-006870-f5w6fw6q 5662 5 an an DT cord-006870-f5w6fw6q 5662 6 ischemic ischemic JJ cord-006870-f5w6fw6q 5662 7 stroke stroke NN cord-006870-f5w6fw6q 5662 8 secondary secondary JJ cord-006870-f5w6fw6q 5662 9 to to IN cord-006870-f5w6fw6q 5662 10 acute acute JJ cord-006870-f5w6fw6q 5662 11 occlusions occlusion NNS cord-006870-f5w6fw6q 5662 12 of of IN cord-006870-f5w6fw6q 5662 13 the the DT cord-006870-f5w6fw6q 5662 14 left left JJ cord-006870-f5w6fw6q 5662 15 ICA ICA NNP cord-006870-f5w6fw6q 5662 16 and and CC cord-006870-f5w6fw6q 5662 17 left leave VBD cord-006870-f5w6fw6q 5662 18 middle middle JJ cord-006870-f5w6fw6q 5662 19 cerebral cerebral JJ cord-006870-f5w6fw6q 5662 20 artery artery NN cord-006870-f5w6fw6q 5662 21 ( ( -LRB- cord-006870-f5w6fw6q 5662 22 MCA MCA NNP cord-006870-f5w6fw6q 5662 23 ) ) -RRB- cord-006870-f5w6fw6q 5662 24 and and CC cord-006870-f5w6fw6q 5662 25 were be VBD cord-006870-f5w6fw6q 5662 26 taken take VBN cord-006870-f5w6fw6q 5662 27 emergently emergently RB cord-006870-f5w6fw6q 5662 28 to to IN cord-006870-f5w6fw6q 5662 29 the the DT cord-006870-f5w6fw6q 5662 30 neurointerventional neurointerventional NNP cord-006870-f5w6fw6q 5662 31 suite suite NN cord-006870-f5w6fw6q 5662 32 for for IN cord-006870-f5w6fw6q 5662 33 carotid carotid JJ cord-006870-f5w6fw6q 5662 34 artery artery NN cord-006870-f5w6fw6q 5662 35 stenting stenting NN cord-006870-f5w6fw6q 5662 36 ( ( -LRB- cord-006870-f5w6fw6q 5662 37 CAS CAS NNP cord-006870-f5w6fw6q 5662 38 ) ) -RRB- cord-006870-f5w6fw6q 5662 39 and and CC cord-006870-f5w6fw6q 5662 40 mechanical mechanical JJ cord-006870-f5w6fw6q 5662 41 embolectomy embolectomy NN cord-006870-f5w6fw6q 5662 42 of of IN cord-006870-f5w6fw6q 5662 43 the the DT cord-006870-f5w6fw6q 5662 44 MCA MCA NNP cord-006870-f5w6fw6q 5662 45 clot clot NN cord-006870-f5w6fw6q 5662 46 . . . cord-006870-f5w6fw6q 5663 1 Heparin heparin JJ cord-006870-f5w6fw6q 5663 2 and and CC cord-006870-f5w6fw6q 5663 3 eptifibatide eptifibatide NN cord-006870-f5w6fw6q 5663 4 were be VBD cord-006870-f5w6fw6q 5663 5 administered administer VBN cord-006870-f5w6fw6q 5663 6 intraoperatively intraoperatively RB cord-006870-f5w6fw6q 5663 7 . . . cord-006870-f5w6fw6q 5664 1 Post post JJ cord-006870-f5w6fw6q 5664 2 - - NN cord-006870-f5w6fw6q 5664 3 procedure procedure JJ cord-006870-f5w6fw6q 5664 4 DynaCT DynaCT NNP cord-006870-f5w6fw6q 5664 5 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5664 6 intracranial intracranial JJ cord-006870-f5w6fw6q 5664 7 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5664 8 complications complication NNS cord-006870-f5w6fw6q 5664 9 . . . cord-006870-f5w6fw6q 5665 1 Dual dual JJ cord-006870-f5w6fw6q 5665 2 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 5665 3 therapy therapy NN cord-006870-f5w6fw6q 5665 4 ( ( -LRB- cord-006870-f5w6fw6q 5665 5 DAPT DAPT NNP cord-006870-f5w6fw6q 5665 6 ) ) -RRB- cord-006870-f5w6fw6q 5665 7 with with IN cord-006870-f5w6fw6q 5665 8 clopidogrel clopidogrel NN cord-006870-f5w6fw6q 5665 9 and and CC cord-006870-f5w6fw6q 5665 10 aspirin aspirin NN cord-006870-f5w6fw6q 5665 11 , , , cord-006870-f5w6fw6q 5665 12 typically typically RB cord-006870-f5w6fw6q 5665 13 initiated initiate VBN cord-006870-f5w6fw6q 5665 14 following follow VBG cord-006870-f5w6fw6q 5665 15 CAS CAS NNP cord-006870-f5w6fw6q 5665 16 , , , cord-006870-f5w6fw6q 5665 17 was be VBD cord-006870-f5w6fw6q 5665 18 deferred defer VBN cord-006870-f5w6fw6q 5665 19 given give VBN cord-006870-f5w6fw6q 5665 20 the the DT cord-006870-f5w6fw6q 5665 21 difficulty difficulty NN cord-006870-f5w6fw6q 5665 22 of of IN cord-006870-f5w6fw6q 5665 23 reversing reverse VBG cord-006870-f5w6fw6q 5665 24 their -PRON- PRP$ cord-006870-f5w6fw6q 5665 25 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 5665 26 effect effect NN cord-006870-f5w6fw6q 5665 27 in in IN cord-006870-f5w6fw6q 5665 28 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5665 29 expansion expansion NN cord-006870-f5w6fw6q 5665 30 . . . cord-006870-f5w6fw6q 5666 1 Instead instead RB cord-006870-f5w6fw6q 5666 2 , , , cord-006870-f5w6fw6q 5666 3 cangrelor cangrelor NNP cord-006870-f5w6fw6q 5666 4 was be VBD cord-006870-f5w6fw6q 5666 5 initiated initiate VBN cord-006870-f5w6fw6q 5666 6 to to TO cord-006870-f5w6fw6q 5666 7 maintain maintain VB cord-006870-f5w6fw6q 5666 8 carotid carotid JJ cord-006870-f5w6fw6q 5666 9 stent stent NN cord-006870-f5w6fw6q 5666 10 patency patency NN cord-006870-f5w6fw6q 5666 11 at at IN cord-006870-f5w6fw6q 5666 12 0.75 0.75 CD cord-006870-f5w6fw6q 5666 13 mcg mcg NN cord-006870-f5w6fw6q 5666 14 / / SYM cord-006870-f5w6fw6q 5666 15 kg kg NNP cord-006870-f5w6fw6q 5666 16 / / SYM cord-006870-f5w6fw6q 5666 17 min min NN cord-006870-f5w6fw6q 5666 18 in in IN cord-006870-f5w6fw6q 5666 19 one one CD cord-006870-f5w6fw6q 5666 20 patient patient NN cord-006870-f5w6fw6q 5666 21 and and CC cord-006870-f5w6fw6q 5666 22 0.5 0.5 CD cord-006870-f5w6fw6q 5666 23 mcg mcg NN cord-006870-f5w6fw6q 5666 24 / / SYM cord-006870-f5w6fw6q 5666 25 kg kg NNP cord-006870-f5w6fw6q 5666 26 / / SYM cord-006870-f5w6fw6q 5666 27 min min NN cord-006870-f5w6fw6q 5666 28 in in IN cord-006870-f5w6fw6q 5666 29 the the DT cord-006870-f5w6fw6q 5666 30 other other JJ cord-006870-f5w6fw6q 5666 31 patient patient NN cord-006870-f5w6fw6q 5666 32 and and CC cord-006870-f5w6fw6q 5666 33 infused infuse VBN cord-006870-f5w6fw6q 5666 34 for for IN cord-006870-f5w6fw6q 5666 35 5.5 5.5 CD cord-006870-f5w6fw6q 5666 36 and and CC cord-006870-f5w6fw6q 5666 37 25 25 CD cord-006870-f5w6fw6q 5666 38 hours hour NNS cord-006870-f5w6fw6q 5666 39 , , , cord-006870-f5w6fw6q 5666 40 respectively respectively RB cord-006870-f5w6fw6q 5666 41 . . . cord-006870-f5w6fw6q 5667 1 Platelet platelet NN cord-006870-f5w6fw6q 5667 2 reactivity reactivity NN cord-006870-f5w6fw6q 5667 3 was be VBD cord-006870-f5w6fw6q 5667 4 trended trend VBN cord-006870-f5w6fw6q 5667 5 with with IN cord-006870-f5w6fw6q 5667 6 the the DT cord-006870-f5w6fw6q 5667 7 VerifyNow VerifyNow NNP cord-006870-f5w6fw6q 5667 8 ® ® NN cord-006870-f5w6fw6q 5667 9 assay assay NN cord-006870-f5w6fw6q 5667 10 and and CC cord-006870-f5w6fw6q 5667 11 used use VBD cord-006870-f5w6fw6q 5667 12 to to TO cord-006870-f5w6fw6q 5667 13 adjust adjust VB cord-006870-f5w6fw6q 5667 14 cangrelor cangrelor NN cord-006870-f5w6fw6q 5667 15 dosing dosing NN cord-006870-f5w6fw6q 5667 16 . . . cord-006870-f5w6fw6q 5668 1 Serial serial JJ cord-006870-f5w6fw6q 5668 2 imaging imaging NN cord-006870-f5w6fw6q 5668 3 was be VBD cord-006870-f5w6fw6q 5668 4 obtained obtain VBN cord-006870-f5w6fw6q 5668 5 to to TO cord-006870-f5w6fw6q 5668 6 monitor monitor VB cord-006870-f5w6fw6q 5668 7 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5668 8 expansion expansion NN cord-006870-f5w6fw6q 5668 9 . . . cord-006870-f5w6fw6q 5669 1 One one CD cord-006870-f5w6fw6q 5669 2 patient patient NN cord-006870-f5w6fw6q 5669 3 was be VBD cord-006870-f5w6fw6q 5669 4 transitioned transition VBN cord-006870-f5w6fw6q 5669 5 to to IN cord-006870-f5w6fw6q 5669 6 oral oral JJ cord-006870-f5w6fw6q 5669 7 DAPT DAPT NNP cord-006870-f5w6fw6q 5669 8 and and CC cord-006870-f5w6fw6q 5669 9 discharged discharge VBN cord-006870-f5w6fw6q 5669 10 while while IN cord-006870-f5w6fw6q 5669 11 the the DT cord-006870-f5w6fw6q 5669 12 other other JJ cord-006870-f5w6fw6q 5669 13 patient patient NN cord-006870-f5w6fw6q 5669 14 deteriorated deteriorate VBD cord-006870-f5w6fw6q 5669 15 neurologically neurologically RB cord-006870-f5w6fw6q 5669 16 from from IN cord-006870-f5w6fw6q 5669 17 malignant malignant JJ cord-006870-f5w6fw6q 5669 18 cerebral cerebral JJ cord-006870-f5w6fw6q 5669 19 edema edema NN cord-006870-f5w6fw6q 5669 20 and and CC cord-006870-f5w6fw6q 5669 21 expired expire VBD cord-006870-f5w6fw6q 5669 22 . . . cord-006870-f5w6fw6q 5670 1 Cangrelor Cangrelor NNP cord-006870-f5w6fw6q 5670 2 may may MD cord-006870-f5w6fw6q 5670 3 be be VB cord-006870-f5w6fw6q 5670 4 useful useful JJ cord-006870-f5w6fw6q 5670 5 following follow VBG cord-006870-f5w6fw6q 5670 6 CAS CAS NNP cord-006870-f5w6fw6q 5670 7 complicated complicate VBN cord-006870-f5w6fw6q 5670 8 by by IN cord-006870-f5w6fw6q 5670 9 intracranial intracranial JJ cord-006870-f5w6fw6q 5670 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5670 11 when when WRB cord-006870-f5w6fw6q 5670 12 the the DT cord-006870-f5w6fw6q 5670 13 need need NN cord-006870-f5w6fw6q 5670 14 to to TO cord-006870-f5w6fw6q 5670 15 maintain maintain VB cord-006870-f5w6fw6q 5670 16 stent stent NN cord-006870-f5w6fw6q 5670 17 patency patency NN cord-006870-f5w6fw6q 5670 18 must must MD cord-006870-f5w6fw6q 5670 19 be be VB cord-006870-f5w6fw6q 5670 20 balanced balance VBN cord-006870-f5w6fw6q 5670 21 with with IN cord-006870-f5w6fw6q 5670 22 the the DT cord-006870-f5w6fw6q 5670 23 risk risk NN cord-006870-f5w6fw6q 5670 24 of of IN cord-006870-f5w6fw6q 5670 25 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5670 26 expansion expansion NN cord-006870-f5w6fw6q 5670 27 . . . cord-006870-f5w6fw6q 5671 1 Further further JJ cord-006870-f5w6fw6q 5671 2 research research NN cord-006870-f5w6fw6q 5671 3 is be VBZ cord-006870-f5w6fw6q 5671 4 warranted warrant VBN cord-006870-f5w6fw6q 5671 5 to to TO cord-006870-f5w6fw6q 5671 6 determine determine VB cord-006870-f5w6fw6q 5671 7 its -PRON- PRP$ cord-006870-f5w6fw6q 5671 8 safety safety NN cord-006870-f5w6fw6q 5671 9 and and CC cord-006870-f5w6fw6q 5671 10 efficacy efficacy NN cord-006870-f5w6fw6q 5671 11 in in IN cord-006870-f5w6fw6q 5671 12 noncoronary noncoronary JJ cord-006870-f5w6fw6q 5671 13 stents stent NNS cord-006870-f5w6fw6q 5671 14 . . . cord-006870-f5w6fw6q 5672 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 5672 2 amyloid amyloid NN cord-006870-f5w6fw6q 5672 3 angiopathy angiopathy NNP cord-006870-f5w6fw6q 5672 4 ( ( -LRB- cord-006870-f5w6fw6q 5672 5 CAA CAA NNP cord-006870-f5w6fw6q 5672 6 ) ) -RRB- cord-006870-f5w6fw6q 5672 7 although although IN cord-006870-f5w6fw6q 5672 8 has have VBZ cord-006870-f5w6fw6q 5672 9 been be VBN cord-006870-f5w6fw6q 5672 10 described describe VBN cord-006870-f5w6fw6q 5672 11 in in IN cord-006870-f5w6fw6q 5672 12 the the DT cord-006870-f5w6fw6q 5672 13 literature literature NN cord-006870-f5w6fw6q 5672 14 , , , cord-006870-f5w6fw6q 5672 15 the the DT cord-006870-f5w6fw6q 5672 16 different different JJ cord-006870-f5w6fw6q 5672 17 categories category NNS cord-006870-f5w6fw6q 5672 18 of of IN cord-006870-f5w6fw6q 5672 19 this this DT cord-006870-f5w6fw6q 5672 20 entity entity NN cord-006870-f5w6fw6q 5672 21 and and CC cord-006870-f5w6fw6q 5672 22 its -PRON- PRP$ cord-006870-f5w6fw6q 5672 23 recognition recognition NN cord-006870-f5w6fw6q 5672 24 and and CC cord-006870-f5w6fw6q 5672 25 subsequent subsequent JJ cord-006870-f5w6fw6q 5672 26 treatment treatment NN cord-006870-f5w6fw6q 5672 27 are be VBP cord-006870-f5w6fw6q 5672 28 still still RB cord-006870-f5w6fw6q 5672 29 elusive elusive JJ cord-006870-f5w6fw6q 5672 30 . . . cord-006870-f5w6fw6q 5673 1 It -PRON- PRP cord-006870-f5w6fw6q 5673 2 is be VBZ cord-006870-f5w6fw6q 5673 3 important important JJ cord-006870-f5w6fw6q 5673 4 for for IN cord-006870-f5w6fw6q 5673 5 neuro neuro NNP cord-006870-f5w6fw6q 5673 6 intensivists intensivists NNP cord-006870-f5w6fw6q 5673 7 to to TO cord-006870-f5w6fw6q 5673 8 recognize recognize VB cord-006870-f5w6fw6q 5673 9 its -PRON- PRP$ cord-006870-f5w6fw6q 5673 10 variable variable JJ cord-006870-f5w6fw6q 5673 11 presentation presentation NN cord-006870-f5w6fw6q 5673 12 . . . cord-006870-f5w6fw6q 5674 1 We -PRON- PRP cord-006870-f5w6fw6q 5674 2 describe describe VBP cord-006870-f5w6fw6q 5674 3 a a DT cord-006870-f5w6fw6q 5674 4 single single JJ cord-006870-f5w6fw6q 5674 5 case case NN cord-006870-f5w6fw6q 5674 6 report report NN cord-006870-f5w6fw6q 5674 7 and and CC cord-006870-f5w6fw6q 5674 8 perform perform VB cord-006870-f5w6fw6q 5674 9 a a DT cord-006870-f5w6fw6q 5674 10 systemic systemic JJ cord-006870-f5w6fw6q 5674 11 review review NN cord-006870-f5w6fw6q 5674 12 . . . cord-006870-f5w6fw6q 5675 1 CAA CAA NNP cord-006870-f5w6fw6q 5675 2 depending depend VBG cord-006870-f5w6fw6q 5675 3 on on IN cord-006870-f5w6fw6q 5675 4 pathology pathology NN cord-006870-f5w6fw6q 5675 5 can can MD cord-006870-f5w6fw6q 5675 6 be be VB cord-006870-f5w6fw6q 5675 7 categorized categorize VBN cord-006870-f5w6fw6q 5675 8 as as IN cord-006870-f5w6fw6q 5675 9 Inflammatory Inflammatory NNP cord-006870-f5w6fw6q 5675 10 - - HYPH cord-006870-f5w6fw6q 5675 11 CAA CAA NNP cord-006870-f5w6fw6q 5675 12 where where WRB cord-006870-f5w6fw6q 5675 13 perivasculitis perivasculitis NN cord-006870-f5w6fw6q 5675 14 is be VBZ cord-006870-f5w6fw6q 5675 15 seen see VBN cord-006870-f5w6fw6q 5675 16 on on IN cord-006870-f5w6fw6q 5675 17 biopsy biopsy NN cord-006870-f5w6fw6q 5675 18 . . . cord-006870-f5w6fw6q 5676 1 This this DT cord-006870-f5w6fw6q 5676 2 causes cause VBZ cord-006870-f5w6fw6q 5676 3 a a DT cord-006870-f5w6fw6q 5676 4 non non JJ cord-006870-f5w6fw6q 5676 5 - - JJ cord-006870-f5w6fw6q 5676 6 destructive destructive JJ cord-006870-f5w6fw6q 5676 7 perivascular perivascular JJ cord-006870-f5w6fw6q 5676 8 inflammatory inflammatory JJ cord-006870-f5w6fw6q 5676 9 infiltration infiltration NN cord-006870-f5w6fw6q 5676 10 and and CC cord-006870-f5w6fw6q 5676 11 amyloid amyloid NN cord-006870-f5w6fw6q 5676 12 deposition deposition NN cord-006870-f5w6fw6q 5676 13 pattern pattern NN cord-006870-f5w6fw6q 5676 14 . . . cord-006870-f5w6fw6q 5677 1 On on IN cord-006870-f5w6fw6q 5677 2 the the DT cord-006870-f5w6fw6q 5677 3 other other JJ cord-006870-f5w6fw6q 5677 4 hand hand NN cord-006870-f5w6fw6q 5677 5 , , , cord-006870-f5w6fw6q 5677 6 Amyloid amyloid NN cord-006870-f5w6fw6q 5677 7 beta beta NN cord-006870-f5w6fw6q 5677 8 related relate VBN cord-006870-f5w6fw6q 5677 9 angitis angitis NNP cord-006870-f5w6fw6q 5677 10 ( ( -LRB- cord-006870-f5w6fw6q 5677 11 ABRA ABRA NNP cord-006870-f5w6fw6q 5677 12 ) ) -RRB- cord-006870-f5w6fw6q 5677 13 results result VBZ cord-006870-f5w6fw6q 5677 14 in in IN cord-006870-f5w6fw6q 5677 15 a a DT cord-006870-f5w6fw6q 5677 16 vasculitis vasculitis NN cord-006870-f5w6fw6q 5677 17 and and CC cord-006870-f5w6fw6q 5677 18 there there EX cord-006870-f5w6fw6q 5677 19 is be VBZ cord-006870-f5w6fw6q 5677 20 predominantly predominantly RB cord-006870-f5w6fw6q 5677 21 granulomatous granulomatous JJ cord-006870-f5w6fw6q 5677 22 angio angio NN cord-006870-f5w6fw6q 5677 23 - - HYPH cord-006870-f5w6fw6q 5677 24 destructive destructive JJ cord-006870-f5w6fw6q 5677 25 inflammatory inflammatory JJ cord-006870-f5w6fw6q 5677 26 mediated mediate VBN cord-006870-f5w6fw6q 5677 27 disease disease NN cord-006870-f5w6fw6q 5677 28 affecting affect VBG cord-006870-f5w6fw6q 5677 29 leptomeningeal leptomeningeal NN cord-006870-f5w6fw6q 5677 30 and and CC cord-006870-f5w6fw6q 5677 31 cortical cortical JJ cord-006870-f5w6fw6q 5677 32 vessels vessel NNS cord-006870-f5w6fw6q 5677 33 characterized characterize VBN cord-006870-f5w6fw6q 5677 34 by by IN cord-006870-f5w6fw6q 5677 35 meningeal meningeal JJ cord-006870-f5w6fw6q 5677 36 lymphocytosis lymphocytosis NN cord-006870-f5w6fw6q 5677 37 and and CC cord-006870-f5w6fw6q 5677 38 abundant abundant JJ cord-006870-f5w6fw6q 5677 39 amyloid amyloid NN cord-006870-f5w6fw6q 5677 40 - - HYPH cord-006870-f5w6fw6q 5677 41 beta beta NN cord-006870-f5w6fw6q 5677 42 deposition deposition NN cord-006870-f5w6fw6q 5677 43 within within IN cord-006870-f5w6fw6q 5677 44 the the DT cord-006870-f5w6fw6q 5677 45 vessel vessel NN cord-006870-f5w6fw6q 5677 46 walls wall NNS cord-006870-f5w6fw6q 5677 47 . . . cord-006870-f5w6fw6q 5678 1 CAA CAA NNP cord-006870-f5w6fw6q 5678 2 on on IN cord-006870-f5w6fw6q 5678 3 the the DT cord-006870-f5w6fw6q 5678 4 other other JJ cord-006870-f5w6fw6q 5678 5 hand hand NN cord-006870-f5w6fw6q 5678 6 results result NNS cord-006870-f5w6fw6q 5678 7 in in IN cord-006870-f5w6fw6q 5678 8 no no DT cord-006870-f5w6fw6q 5678 9 inflammation inflammation NN cord-006870-f5w6fw6q 5678 10 of of IN cord-006870-f5w6fw6q 5678 11 vessels vessel NNS cord-006870-f5w6fw6q 5678 12 but but CC cord-006870-f5w6fw6q 5678 13 rather rather RB cord-006870-f5w6fw6q 5678 14 just just RB cord-006870-f5w6fw6q 5678 15 deposition deposition NN cord-006870-f5w6fw6q 5678 16 of of IN cord-006870-f5w6fw6q 5678 17 amyloid amyloid JJ cord-006870-f5w6fw6q 5678 18 deposition deposition NN cord-006870-f5w6fw6q 5678 19 in in IN cord-006870-f5w6fw6q 5678 20 the the DT cord-006870-f5w6fw6q 5678 21 walls wall NNS cord-006870-f5w6fw6q 5678 22 of of IN cord-006870-f5w6fw6q 5678 23 vessels vessel NNS cord-006870-f5w6fw6q 5678 24 . . . cord-006870-f5w6fw6q 5679 1 We -PRON- PRP cord-006870-f5w6fw6q 5679 2 report report VBP cord-006870-f5w6fw6q 5679 3 a a DT cord-006870-f5w6fw6q 5679 4 case case NN cord-006870-f5w6fw6q 5679 5 of of IN cord-006870-f5w6fw6q 5679 6 a a DT cord-006870-f5w6fw6q 5679 7 82 82 CD cord-006870-f5w6fw6q 5679 8 year year NN cord-006870-f5w6fw6q 5679 9 old old JJ cord-006870-f5w6fw6q 5679 10 man man NN cord-006870-f5w6fw6q 5679 11 with with IN cord-006870-f5w6fw6q 5679 12 an an DT cord-006870-f5w6fw6q 5679 13 extensive extensive JJ cord-006870-f5w6fw6q 5679 14 cardiac cardiac JJ cord-006870-f5w6fw6q 5679 15 history history NN cord-006870-f5w6fw6q 5679 16 , , , cord-006870-f5w6fw6q 5679 17 who who WP cord-006870-f5w6fw6q 5679 18 presented present VBD cord-006870-f5w6fw6q 5679 19 with with IN cord-006870-f5w6fw6q 5679 20 syncope syncope NN cord-006870-f5w6fw6q 5679 21 . . . cord-006870-f5w6fw6q 5680 1 Initial initial JJ cord-006870-f5w6fw6q 5680 2 computed compute VBN cord-006870-f5w6fw6q 5680 3 tomography tomography NN cord-006870-f5w6fw6q 5680 4 ( ( -LRB- cord-006870-f5w6fw6q 5680 5 CT CT NNP cord-006870-f5w6fw6q 5680 6 ) ) -RRB- cord-006870-f5w6fw6q 5680 7 of of IN cord-006870-f5w6fw6q 5680 8 head head NN cord-006870-f5w6fw6q 5680 9 was be VBD cord-006870-f5w6fw6q 5680 10 negative negative JJ cord-006870-f5w6fw6q 5680 11 . . . cord-006870-f5w6fw6q 5681 1 During during IN cord-006870-f5w6fw6q 5681 2 admission admission NN cord-006870-f5w6fw6q 5681 3 , , , cord-006870-f5w6fw6q 5681 4 he -PRON- PRP cord-006870-f5w6fw6q 5681 5 acutely acutely RB cord-006870-f5w6fw6q 5681 6 started start VBD cord-006870-f5w6fw6q 5681 7 having have VBG cord-006870-f5w6fw6q 5681 8 trouble trouble NN cord-006870-f5w6fw6q 5681 9 answering answer VBG cord-006870-f5w6fw6q 5681 10 questions question NNS cord-006870-f5w6fw6q 5681 11 including include VBG cord-006870-f5w6fw6q 5681 12 his -PRON- PRP$ cord-006870-f5w6fw6q 5681 13 name name NN cord-006870-f5w6fw6q 5681 14 , , , cord-006870-f5w6fw6q 5681 15 and and CC cord-006870-f5w6fw6q 5681 16 was be VBD cord-006870-f5w6fw6q 5681 17 unable unable JJ cord-006870-f5w6fw6q 5681 18 to to TO cord-006870-f5w6fw6q 5681 19 communicate communicate VB cord-006870-f5w6fw6q 5681 20 his -PRON- PRP$ cord-006870-f5w6fw6q 5681 21 needs need NNS cord-006870-f5w6fw6q 5681 22 . . . cord-006870-f5w6fw6q 5682 1 Repeat repeat NN cord-006870-f5w6fw6q 5682 2 CT CT NNP cord-006870-f5w6fw6q 5682 3 head head NN cord-006870-f5w6fw6q 5682 4 showed show VBD cord-006870-f5w6fw6q 5682 5 hypodensity hypodensity NN cord-006870-f5w6fw6q 5682 6 in in IN cord-006870-f5w6fw6q 5682 7 left left JJ cord-006870-f5w6fw6q 5682 8 frontal frontal JJ cord-006870-f5w6fw6q 5682 9 region region NN cord-006870-f5w6fw6q 5682 10 which which WDT cord-006870-f5w6fw6q 5682 11 was be VBD cord-006870-f5w6fw6q 5682 12 attributed attribute VBN cord-006870-f5w6fw6q 5682 13 to to IN cord-006870-f5w6fw6q 5682 14 a a DT cord-006870-f5w6fw6q 5682 15 stroke stroke NN cord-006870-f5w6fw6q 5682 16 . . . cord-006870-f5w6fw6q 5683 1 He -PRON- PRP cord-006870-f5w6fw6q 5683 2 than than IN cord-006870-f5w6fw6q 5683 3 developed develop VBD cord-006870-f5w6fw6q 5683 4 complex complex JJ cord-006870-f5w6fw6q 5683 5 partial partial JJ cord-006870-f5w6fw6q 5683 6 seizures seizure NNS cord-006870-f5w6fw6q 5683 7 requiring require VBG cord-006870-f5w6fw6q 5683 8 intubation intubation NN cord-006870-f5w6fw6q 5683 9 and and CC cord-006870-f5w6fw6q 5683 10 seizure seizure NN cord-006870-f5w6fw6q 5683 11 management management NN cord-006870-f5w6fw6q 5683 12 . . . cord-006870-f5w6fw6q 5684 1 Lumbar lumbar JJ cord-006870-f5w6fw6q 5684 2 puncture puncture NN cord-006870-f5w6fw6q 5684 3 showed show VBD cord-006870-f5w6fw6q 5684 4 mild mild JJ cord-006870-f5w6fw6q 5684 5 pleocytosis pleocytosis NN cord-006870-f5w6fw6q 5684 6 . . . cord-006870-f5w6fw6q 5685 1 MRI MRI NNP cord-006870-f5w6fw6q 5685 2 brain brain NN cord-006870-f5w6fw6q 5685 3 showed show VBD cord-006870-f5w6fw6q 5685 4 edematous edematous JJ cord-006870-f5w6fw6q 5685 5 changes change NNS cord-006870-f5w6fw6q 5685 6 of of IN cord-006870-f5w6fw6q 5685 7 the the DT cord-006870-f5w6fw6q 5685 8 left left JJ cord-006870-f5w6fw6q 5685 9 subcortical subcortical JJ cord-006870-f5w6fw6q 5685 10 and and CC cord-006870-f5w6fw6q 5685 11 deep deep JJ cord-006870-f5w6fw6q 5685 12 white white JJ cord-006870-f5w6fw6q 5685 13 matter matter NN cord-006870-f5w6fw6q 5685 14 frontal frontal JJ cord-006870-f5w6fw6q 5685 15 lobe lobe NNP cord-006870-f5w6fw6q 5685 16 region region NN cord-006870-f5w6fw6q 5685 17 which which WDT cord-006870-f5w6fw6q 5685 18 on on IN cord-006870-f5w6fw6q 5685 19 repeat repeat NN cord-006870-f5w6fw6q 5685 20 imaging imaging NN cord-006870-f5w6fw6q 5685 21 subsequently subsequently RB cord-006870-f5w6fw6q 5685 22 worsened worsen VBD cord-006870-f5w6fw6q 5685 23 . . . cord-006870-f5w6fw6q 5686 1 Biopsy Biopsy NNP cord-006870-f5w6fw6q 5686 2 was be VBD cord-006870-f5w6fw6q 5686 3 eventually eventually RB cord-006870-f5w6fw6q 5686 4 performed perform VBN cord-006870-f5w6fw6q 5686 5 which which WDT cord-006870-f5w6fw6q 5686 6 confirmed confirm VBD cord-006870-f5w6fw6q 5686 7 Inflammatory inflammatory JJ cord-006870-f5w6fw6q 5686 8 cerebral cerebral JJ cord-006870-f5w6fw6q 5686 9 amyloid amyloid NN cord-006870-f5w6fw6q 5686 10 angiopathy angiopathy NNP cord-006870-f5w6fw6q 5686 11 . . . cord-006870-f5w6fw6q 5687 1 He -PRON- PRP cord-006870-f5w6fw6q 5687 2 was be VBD cord-006870-f5w6fw6q 5687 3 treated treat VBN cord-006870-f5w6fw6q 5687 4 with with IN cord-006870-f5w6fw6q 5687 5 steroids steroid NNS cord-006870-f5w6fw6q 5687 6 and and CC cord-006870-f5w6fw6q 5687 7 immunosuppression immunosuppression NN cord-006870-f5w6fw6q 5687 8 with with IN cord-006870-f5w6fw6q 5687 9 gradual gradual JJ cord-006870-f5w6fw6q 5687 10 improvement improvement NN cord-006870-f5w6fw6q 5687 11 . . . cord-006870-f5w6fw6q 5688 1 3 3 CD cord-006870-f5w6fw6q 5688 2 month month NN cord-006870-f5w6fw6q 5688 3 follow follow VB cord-006870-f5w6fw6q 5688 4 up up RP cord-006870-f5w6fw6q 5688 5 in in IN cord-006870-f5w6fw6q 5688 6 clinic clinic NN cord-006870-f5w6fw6q 5688 7 with with IN cord-006870-f5w6fw6q 5688 8 continued continued JJ cord-006870-f5w6fw6q 5688 9 improvement improvement NN cord-006870-f5w6fw6q 5688 10 to to IN cord-006870-f5w6fw6q 5688 11 independence independence NN cord-006870-f5w6fw6q 5688 12 . . . cord-006870-f5w6fw6q 5689 1 Recognize recognize VB cord-006870-f5w6fw6q 5689 2 the the DT cord-006870-f5w6fw6q 5689 3 various various JJ cord-006870-f5w6fw6q 5689 4 subtypes subtype NNS cord-006870-f5w6fw6q 5689 5 of of IN cord-006870-f5w6fw6q 5689 6 CAA caa NN cord-006870-f5w6fw6q 5689 7 in in IN cord-006870-f5w6fw6q 5689 8 their -PRON- PRP$ cord-006870-f5w6fw6q 5689 9 pathology pathology NN cord-006870-f5w6fw6q 5689 10 , , , cord-006870-f5w6fw6q 5689 11 presentation presentation NN cord-006870-f5w6fw6q 5689 12 and and CC cord-006870-f5w6fw6q 5689 13 potential potential JJ cord-006870-f5w6fw6q 5689 14 treatment treatment NN cord-006870-f5w6fw6q 5689 15 . . . cord-006870-f5w6fw6q 5690 1 In in IN cord-006870-f5w6fw6q 5690 2 acute acute JJ cord-006870-f5w6fw6q 5690 3 emergency emergency NN cord-006870-f5w6fw6q 5690 4 situations situation NNS cord-006870-f5w6fw6q 5690 5 , , , cord-006870-f5w6fw6q 5690 6 intraosseous intraosseous JJ cord-006870-f5w6fw6q 5690 7 vascular vascular JJ cord-006870-f5w6fw6q 5690 8 access access NN cord-006870-f5w6fw6q 5690 9 represents represent VBZ cord-006870-f5w6fw6q 5690 10 an an DT cord-006870-f5w6fw6q 5690 11 alternative alternative JJ cord-006870-f5w6fw6q 5690 12 route route NN cord-006870-f5w6fw6q 5690 13 of of IN cord-006870-f5w6fw6q 5690 14 vascular vascular JJ cord-006870-f5w6fw6q 5690 15 access access NN cord-006870-f5w6fw6q 5690 16 when when WRB cord-006870-f5w6fw6q 5690 17 peripheral peripheral JJ cord-006870-f5w6fw6q 5690 18 vein vein NN cord-006870-f5w6fw6q 5690 19 insertion insertion NN cord-006870-f5w6fw6q 5690 20 is be VBZ cord-006870-f5w6fw6q 5690 21 difficult difficult JJ cord-006870-f5w6fw6q 5690 22 . . . cord-006870-f5w6fw6q 5691 1 We -PRON- PRP cord-006870-f5w6fw6q 5691 2 present present VBP cord-006870-f5w6fw6q 5691 3 the the DT cord-006870-f5w6fw6q 5691 4 first first JJ cord-006870-f5w6fw6q 5691 5 documented document VBN cord-006870-f5w6fw6q 5691 6 case case NN cord-006870-f5w6fw6q 5691 7 of of IN cord-006870-f5w6fw6q 5691 8 intraosseous intraosseous JJ cord-006870-f5w6fw6q 5691 9 alteplase alteplase NNP cord-006870-f5w6fw6q 5691 10 ( ( -LRB- cord-006870-f5w6fw6q 5691 11 tPA tPA NNP cord-006870-f5w6fw6q 5691 12 ) ) -RRB- cord-006870-f5w6fw6q 5691 13 administration administration NN cord-006870-f5w6fw6q 5691 14 in in IN cord-006870-f5w6fw6q 5691 15 a a DT cord-006870-f5w6fw6q 5691 16 patient patient NN cord-006870-f5w6fw6q 5691 17 with with IN cord-006870-f5w6fw6q 5691 18 acute acute JJ cord-006870-f5w6fw6q 5691 19 ischemic ischemic JJ cord-006870-f5w6fw6q 5691 20 stroke stroke NN cord-006870-f5w6fw6q 5691 21 symptoms symptom NNS cord-006870-f5w6fw6q 5691 22 . . . cord-006870-f5w6fw6q 5692 1 Methods method NNS cord-006870-f5w6fw6q 5692 2 57 57 CD cord-006870-f5w6fw6q 5692 3 year year NN cord-006870-f5w6fw6q 5692 4 old old JJ cord-006870-f5w6fw6q 5692 5 male male NN cord-006870-f5w6fw6q 5692 6 with with IN cord-006870-f5w6fw6q 5692 7 past past JJ cord-006870-f5w6fw6q 5692 8 medical medical JJ cord-006870-f5w6fw6q 5692 9 history history NN cord-006870-f5w6fw6q 5692 10 of of IN cord-006870-f5w6fw6q 5692 11 hypertension hypertension NN cord-006870-f5w6fw6q 5692 12 , , , cord-006870-f5w6fw6q 5692 13 end end JJ cord-006870-f5w6fw6q 5692 14 stage stage NN cord-006870-f5w6fw6q 5692 15 renal renal JJ cord-006870-f5w6fw6q 5692 16 disease disease NN cord-006870-f5w6fw6q 5692 17 , , , cord-006870-f5w6fw6q 5692 18 and and CC cord-006870-f5w6fw6q 5692 19 diabetes diabetes NN cord-006870-f5w6fw6q 5692 20 mellitus mellitus NN cord-006870-f5w6fw6q 5692 21 presented present VBN cord-006870-f5w6fw6q 5692 22 to to IN cord-006870-f5w6fw6q 5692 23 the the DT cord-006870-f5w6fw6q 5692 24 hospital hospital NN cord-006870-f5w6fw6q 5692 25 with with IN cord-006870-f5w6fw6q 5692 26 sudden sudden JJ cord-006870-f5w6fw6q 5692 27 onset onset JJ cord-006870-f5w6fw6q 5692 28 expressive expressive JJ cord-006870-f5w6fw6q 5692 29 aphasia aphasia NN cord-006870-f5w6fw6q 5692 30 and and CC cord-006870-f5w6fw6q 5692 31 right right JJ cord-006870-f5w6fw6q 5692 32 sided sided JJ cord-006870-f5w6fw6q 5692 33 numbness numbness NN cord-006870-f5w6fw6q 5692 34 36 36 CD cord-006870-f5w6fw6q 5692 35 minutes minute NNS cord-006870-f5w6fw6q 5692 36 prior prior RB cord-006870-f5w6fw6q 5692 37 to to IN cord-006870-f5w6fw6q 5692 38 ED ED NNP cord-006870-f5w6fw6q 5692 39 arrival arrival NN cord-006870-f5w6fw6q 5692 40 . . . cord-006870-f5w6fw6q 5693 1 NIHSS NIHSS NNP cord-006870-f5w6fw6q 5693 2 was be VBD cord-006870-f5w6fw6q 5693 3 3 3 CD cord-006870-f5w6fw6q 5693 4 and and CC cord-006870-f5w6fw6q 5693 5 code code NN cord-006870-f5w6fw6q 5693 6 stroke stroke NN cord-006870-f5w6fw6q 5693 7 was be VBD cord-006870-f5w6fw6q 5693 8 activated activate VBN cord-006870-f5w6fw6q 5693 9 . . . cord-006870-f5w6fw6q 5694 1 Patient patient JJ cord-006870-f5w6fw6q 5694 2 blood blood NN cord-006870-f5w6fw6q 5694 3 pressure pressure NN cord-006870-f5w6fw6q 5694 4 was be VBD cord-006870-f5w6fw6q 5694 5 207/102 207/102 CD cord-006870-f5w6fw6q 5694 6 . . . cord-006870-f5w6fw6q 5695 1 CT CT NNP cord-006870-f5w6fw6q 5695 2 head head NN cord-006870-f5w6fw6q 5695 3 did do VBD cord-006870-f5w6fw6q 5695 4 not not RB cord-006870-f5w6fw6q 5695 5 show show VB cord-006870-f5w6fw6q 5695 6 any any DT cord-006870-f5w6fw6q 5695 7 acute acute JJ cord-006870-f5w6fw6q 5695 8 intracranial intracranial JJ cord-006870-f5w6fw6q 5695 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5695 10 . . . cord-006870-f5w6fw6q 5696 1 It -PRON- PRP cord-006870-f5w6fw6q 5696 2 was be VBD cord-006870-f5w6fw6q 5696 3 decided decide VBN cord-006870-f5w6fw6q 5696 4 to to TO cord-006870-f5w6fw6q 5696 5 proceed proceed VB cord-006870-f5w6fw6q 5696 6 with with IN cord-006870-f5w6fw6q 5696 7 thrombolytic thrombolytic NN cord-006870-f5w6fw6q 5696 8 therapy therapy NN cord-006870-f5w6fw6q 5696 9 . . . cord-006870-f5w6fw6q 5697 1 One one CD cord-006870-f5w6fw6q 5697 2 peripheral peripheral JJ cord-006870-f5w6fw6q 5697 3 venous venous JJ cord-006870-f5w6fw6q 5697 4 access access NN cord-006870-f5w6fw6q 5697 5 was be VBD cord-006870-f5w6fw6q 5697 6 obtained obtain VBN cord-006870-f5w6fw6q 5697 7 through through IN cord-006870-f5w6fw6q 5697 8 which which WDT cord-006870-f5w6fw6q 5697 9 nicardipine nicardipine JJ cord-006870-f5w6fw6q 5697 10 drip drip NN cord-006870-f5w6fw6q 5697 11 was be VBD cord-006870-f5w6fw6q 5697 12 started start VBN cord-006870-f5w6fw6q 5697 13 to to TO cord-006870-f5w6fw6q 5697 14 lower lower VB cord-006870-f5w6fw6q 5697 15 the the DT cord-006870-f5w6fw6q 5697 16 blood blood NN cord-006870-f5w6fw6q 5697 17 pressure pressure NN cord-006870-f5w6fw6q 5698 1 however however RB cord-006870-f5w6fw6q 5698 2 second second JJ cord-006870-f5w6fw6q 5698 3 peripheral peripheral JJ cord-006870-f5w6fw6q 5698 4 venous venous JJ cord-006870-f5w6fw6q 5698 5 access access NN cord-006870-f5w6fw6q 5698 6 was be VBD cord-006870-f5w6fw6q 5698 7 attempted attempt VBN cord-006870-f5w6fw6q 5698 8 multiple multiple JJ cord-006870-f5w6fw6q 5698 9 times time NNS cord-006870-f5w6fw6q 5698 10 but but CC cord-006870-f5w6fw6q 5698 11 was be VBD cord-006870-f5w6fw6q 5698 12 unable unable JJ cord-006870-f5w6fw6q 5698 13 to to TO cord-006870-f5w6fw6q 5698 14 be be VB cord-006870-f5w6fw6q 5698 15 obtained obtain VBN cord-006870-f5w6fw6q 5698 16 . . . cord-006870-f5w6fw6q 5699 1 tPA tPA NNP cord-006870-f5w6fw6q 5699 2 is be VBZ cord-006870-f5w6fw6q 5699 3 more more RBR cord-006870-f5w6fw6q 5699 4 effective effective JJ cord-006870-f5w6fw6q 5699 5 the the DT cord-006870-f5w6fw6q 5699 6 faster fast RBR cord-006870-f5w6fw6q 5699 7 it -PRON- PRP cord-006870-f5w6fw6q 5699 8 is be VBZ cord-006870-f5w6fw6q 5699 9 administrated administrate VBN cord-006870-f5w6fw6q 5699 10 , , , cord-006870-f5w6fw6q 5699 11 and and CC cord-006870-f5w6fw6q 5699 12 there there EX cord-006870-f5w6fw6q 5699 13 was be VBD cord-006870-f5w6fw6q 5699 14 no no DT cord-006870-f5w6fw6q 5699 15 known know VBN cord-006870-f5w6fw6q 5699 16 contraindications contraindication NNS cord-006870-f5w6fw6q 5699 17 to to IN cord-006870-f5w6fw6q 5699 18 administering administer VBG cord-006870-f5w6fw6q 5699 19 tPA tPA NNP cord-006870-f5w6fw6q 5699 20 via via IN cord-006870-f5w6fw6q 5699 21 intraosseous intraosseous JJ cord-006870-f5w6fw6q 5699 22 access access NNP cord-006870-f5w6fw6q 5699 23 ( ( -LRB- cord-006870-f5w6fw6q 5699 24 IO IO NNP cord-006870-f5w6fw6q 5699 25 ) ) -RRB- cord-006870-f5w6fw6q 5699 26 . . . cord-006870-f5w6fw6q 5700 1 We -PRON- PRP cord-006870-f5w6fw6q 5700 2 report report VBP cord-006870-f5w6fw6q 5700 3 the the DT cord-006870-f5w6fw6q 5700 4 first first JJ cord-006870-f5w6fw6q 5700 5 known know VBN cord-006870-f5w6fw6q 5700 6 case case NN cord-006870-f5w6fw6q 5700 7 of of IN cord-006870-f5w6fw6q 5700 8 successful successful JJ cord-006870-f5w6fw6q 5700 9 and and CC cord-006870-f5w6fw6q 5700 10 safe safe JJ cord-006870-f5w6fw6q 5700 11 administration administration NN cord-006870-f5w6fw6q 5700 12 of of IN cord-006870-f5w6fw6q 5700 13 fibrinolytic fibrinolytic NNP cord-006870-f5w6fw6q 5700 14 therapy therapy NN cord-006870-f5w6fw6q 5700 15 through through IN cord-006870-f5w6fw6q 5700 16 the the DT cord-006870-f5w6fw6q 5700 17 intraosseous intraosseous JJ cord-006870-f5w6fw6q 5700 18 route route NN cord-006870-f5w6fw6q 5700 19 in in IN cord-006870-f5w6fw6q 5700 20 a a DT cord-006870-f5w6fw6q 5700 21 patient patient NN cord-006870-f5w6fw6q 5700 22 with with IN cord-006870-f5w6fw6q 5700 23 acute acute JJ cord-006870-f5w6fw6q 5700 24 ischemic ischemic JJ cord-006870-f5w6fw6q 5700 25 stroke stroke NN cord-006870-f5w6fw6q 5700 26 symptoms symptom NNS cord-006870-f5w6fw6q 5700 27 . . . cord-006870-f5w6fw6q 5701 1 Intraosseous intraosseous JJ cord-006870-f5w6fw6q 5701 2 access access NN cord-006870-f5w6fw6q 5701 3 has have VBZ cord-006870-f5w6fw6q 5701 4 been be VBN cord-006870-f5w6fw6q 5701 5 considered consider VBN cord-006870-f5w6fw6q 5701 6 to to TO cord-006870-f5w6fw6q 5701 7 be be VB cord-006870-f5w6fw6q 5701 8 more more RBR cord-006870-f5w6fw6q 5701 9 invasive invasive JJ cord-006870-f5w6fw6q 5701 10 than than IN cord-006870-f5w6fw6q 5701 11 intravenous intravenous JJ cord-006870-f5w6fw6q 5701 12 ( ( -LRB- cord-006870-f5w6fw6q 5701 13 IV IV NNP cord-006870-f5w6fw6q 5701 14 ) ) -RRB- cord-006870-f5w6fw6q 5701 15 and and CC cord-006870-f5w6fw6q 5701 16 carries carry VBZ cord-006870-f5w6fw6q 5701 17 theoretical theoretical JJ cord-006870-f5w6fw6q 5701 18 risk risk NN cord-006870-f5w6fw6q 5701 19 of of IN cord-006870-f5w6fw6q 5701 20 bleeding bleed VBG cord-006870-f5w6fw6q 5702 1 however however RB cord-006870-f5w6fw6q 5702 2 we -PRON- PRP cord-006870-f5w6fw6q 5702 3 were be VBD cord-006870-f5w6fw6q 5702 4 able able JJ cord-006870-f5w6fw6q 5702 5 to to TO cord-006870-f5w6fw6q 5702 6 demonstrate demonstrate VB cord-006870-f5w6fw6q 5702 7 tPA tPA NNP cord-006870-f5w6fw6q 5702 8 administration administration NN cord-006870-f5w6fw6q 5702 9 through through IN cord-006870-f5w6fw6q 5702 10 IO IO NNP cord-006870-f5w6fw6q 5702 11 without without IN cord-006870-f5w6fw6q 5702 12 any any DT cord-006870-f5w6fw6q 5702 13 local local JJ cord-006870-f5w6fw6q 5702 14 or or CC cord-006870-f5w6fw6q 5702 15 systemic systemic JJ cord-006870-f5w6fw6q 5702 16 complications complication NNS cord-006870-f5w6fw6q 5702 17 . . . cord-006870-f5w6fw6q 5703 1 The the DT cord-006870-f5w6fw6q 5703 2 bioavailability bioavailability NN cord-006870-f5w6fw6q 5703 3 of of IN cord-006870-f5w6fw6q 5703 4 alteplase alteplase NN cord-006870-f5w6fw6q 5703 5 through through IN cord-006870-f5w6fw6q 5703 6 IO IO NNP cord-006870-f5w6fw6q 5703 7 access access NN cord-006870-f5w6fw6q 5703 8 has have VBZ cord-006870-f5w6fw6q 5703 9 not not RB cord-006870-f5w6fw6q 5703 10 been be VBN cord-006870-f5w6fw6q 5703 11 studied study VBN cord-006870-f5w6fw6q 5703 12 however however WRB cord-006870-f5w6fw6q 5703 13 it -PRON- PRP cord-006870-f5w6fw6q 5703 14 is be VBZ cord-006870-f5w6fw6q 5703 15 considered consider VBN cord-006870-f5w6fw6q 5703 16 to to TO cord-006870-f5w6fw6q 5703 17 be be VB cord-006870-f5w6fw6q 5703 18 close close JJ cord-006870-f5w6fw6q 5703 19 to to IN cord-006870-f5w6fw6q 5703 20 IV IV NNP cord-006870-f5w6fw6q 5703 21 infusion infusion NN cord-006870-f5w6fw6q 5703 22 in in IN cord-006870-f5w6fw6q 5703 23 case case NN cord-006870-f5w6fw6q 5703 24 of of IN cord-006870-f5w6fw6q 5703 25 morphine morphine NN cord-006870-f5w6fw6q 5703 26 and and CC cord-006870-f5w6fw6q 5703 27 vasopressors vasopressor NNS cord-006870-f5w6fw6q 5703 28 . . . cord-006870-f5w6fw6q 5704 1 No no DT cord-006870-f5w6fw6q 5704 2 studies study NNS cord-006870-f5w6fw6q 5704 3 negate negate VBP cord-006870-f5w6fw6q 5704 4 or or CC cord-006870-f5w6fw6q 5704 5 support support VBP cord-006870-f5w6fw6q 5704 6 the the DT cord-006870-f5w6fw6q 5704 7 use use NN cord-006870-f5w6fw6q 5704 8 of of IN cord-006870-f5w6fw6q 5704 9 intraosseous intraosseous JJ cord-006870-f5w6fw6q 5704 10 access access NN cord-006870-f5w6fw6q 5704 11 in in IN cord-006870-f5w6fw6q 5704 12 stroke stroke NN cord-006870-f5w6fw6q 5704 13 patients patient NNS cord-006870-f5w6fw6q 5704 14 . . . cord-006870-f5w6fw6q 5705 1 Contraindications contraindication NNS cord-006870-f5w6fw6q 5705 2 are be VBP cord-006870-f5w6fw6q 5705 3 few few JJ cord-006870-f5w6fw6q 5705 4 and and CC cord-006870-f5w6fw6q 5705 5 complications complication NNS cord-006870-f5w6fw6q 5705 6 are be VBP cord-006870-f5w6fw6q 5705 7 uncommon uncommon JJ cord-006870-f5w6fw6q 5705 8 . . . cord-006870-f5w6fw6q 5706 1 The the DT cord-006870-f5w6fw6q 5706 2 findings finding NNS cord-006870-f5w6fw6q 5706 3 of of IN cord-006870-f5w6fw6q 5706 4 our -PRON- PRP$ cord-006870-f5w6fw6q 5706 5 case case NN cord-006870-f5w6fw6q 5706 6 report report NN cord-006870-f5w6fw6q 5706 7 suggest suggest VBP cord-006870-f5w6fw6q 5706 8 that that IN cord-006870-f5w6fw6q 5706 9 intraosseous intraosseous JJ cord-006870-f5w6fw6q 5706 10 cannulation cannulation NN cord-006870-f5w6fw6q 5706 11 may may MD cord-006870-f5w6fw6q 5706 12 be be VB cord-006870-f5w6fw6q 5706 13 safely safely RB cord-006870-f5w6fw6q 5706 14 used use VBN cord-006870-f5w6fw6q 5706 15 for for IN cord-006870-f5w6fw6q 5706 16 fibrinolysis fibrinolysis NN cord-006870-f5w6fw6q 5706 17 in in IN cord-006870-f5w6fw6q 5706 18 acute acute JJ cord-006870-f5w6fw6q 5706 19 ischemic ischemic JJ cord-006870-f5w6fw6q 5706 20 stroke stroke NN cord-006870-f5w6fw6q 5706 21 patients patient NNS cord-006870-f5w6fw6q 5706 22 with with IN cord-006870-f5w6fw6q 5706 23 difficult difficult JJ cord-006870-f5w6fw6q 5706 24 peripheral peripheral JJ cord-006870-f5w6fw6q 5706 25 venous venous JJ cord-006870-f5w6fw6q 5706 26 access access NN cord-006870-f5w6fw6q 5706 27 in in IN cord-006870-f5w6fw6q 5706 28 in in IN cord-006870-f5w6fw6q 5706 29 - - HYPH cord-006870-f5w6fw6q 5706 30 hospital hospital NN cord-006870-f5w6fw6q 5706 31 or or CC cord-006870-f5w6fw6q 5706 32 out out RB cord-006870-f5w6fw6q 5706 33 - - HYPH cord-006870-f5w6fw6q 5706 34 of of IN cord-006870-f5w6fw6q 5706 35 - - HYPH cord-006870-f5w6fw6q 5706 36 hospital hospital NN cord-006870-f5w6fw6q 5706 37 setting setting NN cord-006870-f5w6fw6q 5706 38 . . . cord-006870-f5w6fw6q 5707 1 Tufts Tufts NNP cord-006870-f5w6fw6q 5707 2 Medical Medical NNP cord-006870-f5w6fw6q 5707 3 Center Center NNP cord-006870-f5w6fw6q 5707 4 , , , cord-006870-f5w6fw6q 5707 5 Boston Boston NNP cord-006870-f5w6fw6q 5707 6 , , , cord-006870-f5w6fw6q 5707 7 Massachusetts Massachusetts NNP cord-006870-f5w6fw6q 5707 8 , , , cord-006870-f5w6fw6q 5707 9 USA USA NNP cord-006870-f5w6fw6q 5708 1 We -PRON- PRP cord-006870-f5w6fw6q 5708 2 report report VBP cord-006870-f5w6fw6q 5708 3 a a DT cord-006870-f5w6fw6q 5708 4 case case NN cord-006870-f5w6fw6q 5708 5 of of IN cord-006870-f5w6fw6q 5708 6 a a DT cord-006870-f5w6fw6q 5708 7 pregnant pregnant JJ cord-006870-f5w6fw6q 5708 8 patient patient NN cord-006870-f5w6fw6q 5708 9 with with IN cord-006870-f5w6fw6q 5708 10 bilateral bilateral JJ cord-006870-f5w6fw6q 5708 11 ovarian ovarian JJ cord-006870-f5w6fw6q 5708 12 teratomas teratoma NNS cord-006870-f5w6fw6q 5708 13 who who WP cord-006870-f5w6fw6q 5708 14 presented present VBD cord-006870-f5w6fw6q 5708 15 with with IN cord-006870-f5w6fw6q 5708 16 treatment treatment NN cord-006870-f5w6fw6q 5708 17 refractory refractory JJ cord-006870-f5w6fw6q 5708 18 NMDA NMDA NNP cord-006870-f5w6fw6q 5708 19 receptor receptor NN cord-006870-f5w6fw6q 5708 20 encephalitis encephalitis RB cord-006870-f5w6fw6q 5708 21 despite despite IN cord-006870-f5w6fw6q 5708 22 removal removal NN cord-006870-f5w6fw6q 5708 23 of of IN cord-006870-f5w6fw6q 5708 24 bilateral bilateral JJ cord-006870-f5w6fw6q 5708 25 teratomas teratoma NNS cord-006870-f5w6fw6q 5708 26 , , , cord-006870-f5w6fw6q 5708 27 successfully successfully RB cord-006870-f5w6fw6q 5708 28 treated treat VBN cord-006870-f5w6fw6q 5708 29 with with IN cord-006870-f5w6fw6q 5708 30 Rituximab Rituximab NNP cord-006870-f5w6fw6q 5708 31 . . . cord-006870-f5w6fw6q 5709 1 Case case NN cord-006870-f5w6fw6q 5709 2 report report NN cord-006870-f5w6fw6q 5709 3 and and CC cord-006870-f5w6fw6q 5709 4 discussion discussion NN cord-006870-f5w6fw6q 5709 5 of of IN cord-006870-f5w6fw6q 5709 6 treatment treatment NN cord-006870-f5w6fw6q 5709 7 and and CC cord-006870-f5w6fw6q 5709 8 outcome outcome NN cord-006870-f5w6fw6q 5709 9 . . . cord-006870-f5w6fw6q 5710 1 25 25 CD cord-006870-f5w6fw6q 5710 2 year year NN cord-006870-f5w6fw6q 5710 3 old old JJ cord-006870-f5w6fw6q 5710 4 22 22 CD cord-006870-f5w6fw6q 5710 5 weeks week NNS cord-006870-f5w6fw6q 5710 6 pregnant pregnant JJ cord-006870-f5w6fw6q 5710 7 female female NN cord-006870-f5w6fw6q 5710 8 with with IN cord-006870-f5w6fw6q 5710 9 known know VBN cord-006870-f5w6fw6q 5710 10 ovarian ovarian JJ cord-006870-f5w6fw6q 5710 11 cysts cyst NNS cord-006870-f5w6fw6q 5710 12 who who WP cord-006870-f5w6fw6q 5710 13 presented present VBD cord-006870-f5w6fw6q 5710 14 with with IN cord-006870-f5w6fw6q 5710 15 one one CD cord-006870-f5w6fw6q 5710 16 week week NN cord-006870-f5w6fw6q 5710 17 of of IN cord-006870-f5w6fw6q 5710 18 confusion confusion NN cord-006870-f5w6fw6q 5710 19 and and CC cord-006870-f5w6fw6q 5710 20 subsequent subsequent JJ cord-006870-f5w6fw6q 5710 21 status status NN cord-006870-f5w6fw6q 5710 22 epilepticus epilepticus NN cord-006870-f5w6fw6q 5710 23 . . . cord-006870-f5w6fw6q 5711 1 She -PRON- PRP cord-006870-f5w6fw6q 5711 2 was be VBD cord-006870-f5w6fw6q 5711 3 started start VBN cord-006870-f5w6fw6q 5711 4 on on IN cord-006870-f5w6fw6q 5711 5 empiric empiric JJ cord-006870-f5w6fw6q 5711 6 treatment treatment NN cord-006870-f5w6fw6q 5711 7 with with IN cord-006870-f5w6fw6q 5711 8 IVIG IVIG NNP cord-006870-f5w6fw6q 5711 9 while while IN cord-006870-f5w6fw6q 5711 10 undergoing undergo VBG cord-006870-f5w6fw6q 5711 11 workup workup NN cord-006870-f5w6fw6q 5711 12 . . . cord-006870-f5w6fw6q 5712 1 NMDA NMDA NNP cord-006870-f5w6fw6q 5712 2 receptor receptor NN cord-006870-f5w6fw6q 5712 3 antibody antibody NN cord-006870-f5w6fw6q 5712 4 was be VBD cord-006870-f5w6fw6q 5712 5 confirmed confirm VBN cord-006870-f5w6fw6q 5712 6 . . . cord-006870-f5w6fw6q 5713 1 Left leave VBN cord-006870-f5w6fw6q 5713 2 oophorectomy oophorectomy NN cord-006870-f5w6fw6q 5713 3 and and CC cord-006870-f5w6fw6q 5713 4 right right JJ cord-006870-f5w6fw6q 5713 5 ovarian ovarian NN cord-006870-f5w6fw6q 5713 6 cystectomy cystectomy NN cord-006870-f5w6fw6q 5713 7 were be VBD cord-006870-f5w6fw6q 5713 8 performed perform VBN cord-006870-f5w6fw6q 5713 9 , , , cord-006870-f5w6fw6q 5713 10 both both DT cord-006870-f5w6fw6q 5713 11 of of IN cord-006870-f5w6fw6q 5713 12 which which WDT cord-006870-f5w6fw6q 5713 13 confirmed confirm VBD cord-006870-f5w6fw6q 5713 14 ovarian ovarian JJ cord-006870-f5w6fw6q 5713 15 teratoma teratoma NN cord-006870-f5w6fw6q 5713 16 . . . cord-006870-f5w6fw6q 5714 1 She -PRON- PRP cord-006870-f5w6fw6q 5714 2 was be VBD cord-006870-f5w6fw6q 5714 3 given give VBN cord-006870-f5w6fw6q 5714 4 high high JJ cord-006870-f5w6fw6q 5714 5 dose dose NN cord-006870-f5w6fw6q 5714 6 steroids steroid NNS cord-006870-f5w6fw6q 5714 7 . . . cord-006870-f5w6fw6q 5715 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 5715 2 worsening worsen VBG cord-006870-f5w6fw6q 5715 3 condition condition NN cord-006870-f5w6fw6q 5715 4 prompted prompt VBD cord-006870-f5w6fw6q 5715 5 consideration consideration NN cord-006870-f5w6fw6q 5715 6 of of IN cord-006870-f5w6fw6q 5715 7 additional additional JJ cord-006870-f5w6fw6q 5715 8 agents agent NNS cord-006870-f5w6fw6q 5715 9 . . . cord-006870-f5w6fw6q 5716 1 Plasma plasma NN cord-006870-f5w6fw6q 5716 2 exchange exchange NN cord-006870-f5w6fw6q 5716 3 and and CC cord-006870-f5w6fw6q 5716 4 Rituximab Rituximab NNPS cord-006870-f5w6fw6q 5716 5 were be VBD cord-006870-f5w6fw6q 5716 6 initiated initiate VBN cord-006870-f5w6fw6q 5716 7 and and CC cord-006870-f5w6fw6q 5716 8 then then RB cord-006870-f5w6fw6q 5716 9 she -PRON- PRP cord-006870-f5w6fw6q 5716 10 was be VBD cord-006870-f5w6fw6q 5716 11 continued continue VBN cord-006870-f5w6fw6q 5716 12 on on IN cord-006870-f5w6fw6q 5716 13 Rituximab Rituximab NNP cord-006870-f5w6fw6q 5716 14 alone alone JJ cord-006870-f5w6fw6q 5716 15 . . . cord-006870-f5w6fw6q 5717 1 She -PRON- PRP cord-006870-f5w6fw6q 5717 2 improved improve VBD cord-006870-f5w6fw6q 5717 3 dramatically dramatically RB cord-006870-f5w6fw6q 5717 4 over over IN cord-006870-f5w6fw6q 5717 5 six six CD cord-006870-f5w6fw6q 5717 6 weeks week NNS cord-006870-f5w6fw6q 5717 7 and and CC cord-006870-f5w6fw6q 5717 8 delivered deliver VBN cord-006870-f5w6fw6q 5717 9 at at IN cord-006870-f5w6fw6q 5717 10 full full JJ cord-006870-f5w6fw6q 5717 11 term term NN cord-006870-f5w6fw6q 5717 12 via via IN cord-006870-f5w6fw6q 5717 13 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5717 14 vaginal vaginal JJ cord-006870-f5w6fw6q 5717 15 delivery delivery NN cord-006870-f5w6fw6q 5717 16 . . . cord-006870-f5w6fw6q 5718 1 At at IN cord-006870-f5w6fw6q 5718 2 one one CD cord-006870-f5w6fw6q 5718 3 year year NN cord-006870-f5w6fw6q 5718 4 follow follow VB cord-006870-f5w6fw6q 5718 5 up up RP cord-006870-f5w6fw6q 5718 6 , , , cord-006870-f5w6fw6q 5718 7 the the DT cord-006870-f5w6fw6q 5718 8 child child NN cord-006870-f5w6fw6q 5718 9 was be VBD cord-006870-f5w6fw6q 5718 10 healthy healthy JJ cord-006870-f5w6fw6q 5718 11 and and CC cord-006870-f5w6fw6q 5718 12 meeting meet VBG cord-006870-f5w6fw6q 5718 13 appropriate appropriate JJ cord-006870-f5w6fw6q 5718 14 milestones milestone NNS cord-006870-f5w6fw6q 5718 15 . . . cord-006870-f5w6fw6q 5719 1 We -PRON- PRP cord-006870-f5w6fw6q 5719 2 report report VBP cord-006870-f5w6fw6q 5719 3 the the DT cord-006870-f5w6fw6q 5719 4 use use NN cord-006870-f5w6fw6q 5719 5 of of IN cord-006870-f5w6fw6q 5719 6 rituximab rituximab NN cord-006870-f5w6fw6q 5719 7 for for IN cord-006870-f5w6fw6q 5719 8 safe safe JJ cord-006870-f5w6fw6q 5719 9 and and CC cord-006870-f5w6fw6q 5719 10 successful successful JJ cord-006870-f5w6fw6q 5719 11 treatment treatment NN cord-006870-f5w6fw6q 5719 12 of of IN cord-006870-f5w6fw6q 5719 13 NMDA NMDA NNP cord-006870-f5w6fw6q 5719 14 receptor receptor NN cord-006870-f5w6fw6q 5719 15 encephalitis encephalitis RB cord-006870-f5w6fw6q 5719 16 in in IN cord-006870-f5w6fw6q 5719 17 a a DT cord-006870-f5w6fw6q 5719 18 gravid gravid JJ cord-006870-f5w6fw6q 5719 19 female female NN cord-006870-f5w6fw6q 5719 20 . . . cord-006870-f5w6fw6q 5720 1 Neovascular neovascular JJ cord-006870-f5w6fw6q 5720 2 glaucoma glaucoma NN cord-006870-f5w6fw6q 5720 3 ( ( -LRB- cord-006870-f5w6fw6q 5720 4 NVG NVG NNP cord-006870-f5w6fw6q 5720 5 ) ) -RRB- cord-006870-f5w6fw6q 5720 6 is be VBZ cord-006870-f5w6fw6q 5720 7 a a DT cord-006870-f5w6fw6q 5720 8 known know VBN cord-006870-f5w6fw6q 5720 9 complication complication NN cord-006870-f5w6fw6q 5720 10 of of IN cord-006870-f5w6fw6q 5720 11 carotid carotid JJ cord-006870-f5w6fw6q 5720 12 endarterectomy endarterectomy NN cord-006870-f5w6fw6q 5720 13 in in IN cord-006870-f5w6fw6q 5720 14 patients patient NNS cord-006870-f5w6fw6q 5720 15 with with IN cord-006870-f5w6fw6q 5720 16 carotid carotid JJ cord-006870-f5w6fw6q 5720 17 stenosis stenosis NN cord-006870-f5w6fw6q 5720 18 . . . cord-006870-f5w6fw6q 5721 1 There there EX cord-006870-f5w6fw6q 5721 2 are be VBP cord-006870-f5w6fw6q 5721 3 no no DT cord-006870-f5w6fw6q 5721 4 previous previous JJ cord-006870-f5w6fw6q 5721 5 reports report NNS cord-006870-f5w6fw6q 5721 6 of of IN cord-006870-f5w6fw6q 5721 7 acute acute JJ cord-006870-f5w6fw6q 5721 8 NVG NVG NNP cord-006870-f5w6fw6q 5721 9 refractory refractory JJ cord-006870-f5w6fw6q 5721 10 to to IN cord-006870-f5w6fw6q 5721 11 medical medical JJ cord-006870-f5w6fw6q 5721 12 treatment treatment NN cord-006870-f5w6fw6q 5721 13 following follow VBG cord-006870-f5w6fw6q 5721 14 carotid carotid JJ cord-006870-f5w6fw6q 5721 15 artery artery NN cord-006870-f5w6fw6q 5721 16 stenting stenting NN cord-006870-f5w6fw6q 5721 17 ( ( -LRB- cord-006870-f5w6fw6q 5721 18 CAS CAS NNP cord-006870-f5w6fw6q 5721 19 ) ) -RRB- cord-006870-f5w6fw6q 5721 20 . . . cord-006870-f5w6fw6q 5722 1 We -PRON- PRP cord-006870-f5w6fw6q 5722 2 report report VBP cord-006870-f5w6fw6q 5722 3 a a DT cord-006870-f5w6fw6q 5722 4 patient patient NN cord-006870-f5w6fw6q 5722 5 who who WP cord-006870-f5w6fw6q 5722 6 needed need VBD cord-006870-f5w6fw6q 5722 7 surgical surgical JJ cord-006870-f5w6fw6q 5722 8 treatment treatment NN cord-006870-f5w6fw6q 5722 9 for for IN cord-006870-f5w6fw6q 5722 10 acute acute JJ cord-006870-f5w6fw6q 5722 11 exacerbation exacerbation NN cord-006870-f5w6fw6q 5722 12 of of IN cord-006870-f5w6fw6q 5722 13 NVG NVG NNP cord-006870-f5w6fw6q 5722 14 following follow VBG cord-006870-f5w6fw6q 5722 15 CAS CAS NNP cord-006870-f5w6fw6q 5722 16 . . . cord-006870-f5w6fw6q 5723 1 A a DT cord-006870-f5w6fw6q 5723 2 56-year 56-year JJ cord-006870-f5w6fw6q 5723 3 - - HYPH cord-006870-f5w6fw6q 5723 4 old old JJ cord-006870-f5w6fw6q 5723 5 man man NN cord-006870-f5w6fw6q 5723 6 with with IN cord-006870-f5w6fw6q 5723 7 hypertension hypertension NN cord-006870-f5w6fw6q 5723 8 , , , cord-006870-f5w6fw6q 5723 9 diabetes diabetes NN cord-006870-f5w6fw6q 5723 10 , , , cord-006870-f5w6fw6q 5723 11 and and CC cord-006870-f5w6fw6q 5723 12 hypercholesterolemia hypercholesterolemia NN cord-006870-f5w6fw6q 5723 13 presented present VBN cord-006870-f5w6fw6q 5723 14 with with IN cord-006870-f5w6fw6q 5723 15 recurrent recurrent JJ cord-006870-f5w6fw6q 5723 16 transient transient JJ cord-006870-f5w6fw6q 5723 17 weakness weakness NN cord-006870-f5w6fw6q 5723 18 in in IN cord-006870-f5w6fw6q 5723 19 his -PRON- PRP$ cord-006870-f5w6fw6q 5723 20 right right JJ cord-006870-f5w6fw6q 5723 21 hand hand NN cord-006870-f5w6fw6q 5723 22 . . . cord-006870-f5w6fw6q 5724 1 Fifteen fifteen CD cord-006870-f5w6fw6q 5724 2 days day NNS cord-006870-f5w6fw6q 5724 3 before before IN cord-006870-f5w6fw6q 5724 4 presentation presentation NN cord-006870-f5w6fw6q 5724 5 , , , cord-006870-f5w6fw6q 5724 6 he -PRON- PRP cord-006870-f5w6fw6q 5724 7 had have VBD cord-006870-f5w6fw6q 5724 8 experienced experience VBN cord-006870-f5w6fw6q 5724 9 acute acute JJ cord-006870-f5w6fw6q 5724 10 loss loss NN cord-006870-f5w6fw6q 5724 11 of of IN cord-006870-f5w6fw6q 5724 12 vision vision NN cord-006870-f5w6fw6q 5724 13 on on IN cord-006870-f5w6fw6q 5724 14 the the DT cord-006870-f5w6fw6q 5724 15 left left JJ cord-006870-f5w6fw6q 5724 16 side side NN cord-006870-f5w6fw6q 5724 17 because because IN cord-006870-f5w6fw6q 5724 18 of of IN cord-006870-f5w6fw6q 5724 19 central central JJ cord-006870-f5w6fw6q 5724 20 retinal retinal JJ cord-006870-f5w6fw6q 5724 21 artery artery NN cord-006870-f5w6fw6q 5724 22 occlusion occlusion NN cord-006870-f5w6fw6q 5724 23 . . . cord-006870-f5w6fw6q 5725 1 Magnetic magnetic JJ cord-006870-f5w6fw6q 5725 2 resonance resonance NN cord-006870-f5w6fw6q 5725 3 imaging imaging NN cord-006870-f5w6fw6q 5725 4 of of IN cord-006870-f5w6fw6q 5725 5 the the DT cord-006870-f5w6fw6q 5725 6 brain brain NN cord-006870-f5w6fw6q 5725 7 was be VBD cord-006870-f5w6fw6q 5725 8 unremarkable unremarkable JJ cord-006870-f5w6fw6q 5725 9 . . . cord-006870-f5w6fw6q 5726 1 Conventional conventional JJ cord-006870-f5w6fw6q 5726 2 angiography angiography NN cord-006870-f5w6fw6q 5726 3 showed show VBD cord-006870-f5w6fw6q 5726 4 an an DT cord-006870-f5w6fw6q 5726 5 occlusion occlusion NN cord-006870-f5w6fw6q 5726 6 of of IN cord-006870-f5w6fw6q 5726 7 the the DT cord-006870-f5w6fw6q 5726 8 left left JJ cord-006870-f5w6fw6q 5726 9 proximal proximal JJ cord-006870-f5w6fw6q 5726 10 internal internal JJ cord-006870-f5w6fw6q 5726 11 carotid carotid JJ cord-006870-f5w6fw6q 5726 12 artery artery NN cord-006870-f5w6fw6q 5726 13 . . . cord-006870-f5w6fw6q 5727 1 Ophthalmological ophthalmological JJ cord-006870-f5w6fw6q 5727 2 evaluation evaluation NN cord-006870-f5w6fw6q 5727 3 before before IN cord-006870-f5w6fw6q 5727 4 CAS CAS NNP cord-006870-f5w6fw6q 5727 5 showed show VBD cord-006870-f5w6fw6q 5727 6 neovascularization neovascularization NN cord-006870-f5w6fw6q 5727 7 of of IN cord-006870-f5w6fw6q 5727 8 the the DT cord-006870-f5w6fw6q 5727 9 iris iris NN cord-006870-f5w6fw6q 5727 10 and and CC cord-006870-f5w6fw6q 5727 11 a a DT cord-006870-f5w6fw6q 5727 12 normal normal JJ cord-006870-f5w6fw6q 5727 13 intraocular intraocular JJ cord-006870-f5w6fw6q 5727 14 pressure pressure NN cord-006870-f5w6fw6q 5727 15 ( ( -LRB- cord-006870-f5w6fw6q 5727 16 IOP IOP NNP cord-006870-f5w6fw6q 5727 17 ) ) -RRB- cord-006870-f5w6fw6q 5727 18 of of IN cord-006870-f5w6fw6q 5727 19 14 14 CD cord-006870-f5w6fw6q 5727 20 mm mm CD cord-006870-f5w6fw6q 5727 21 Hg Hg NNP cord-006870-f5w6fw6q 5727 22 in in IN cord-006870-f5w6fw6q 5727 23 the the DT cord-006870-f5w6fw6q 5727 24 left left JJ cord-006870-f5w6fw6q 5727 25 eye eye NN cord-006870-f5w6fw6q 5727 26 . . . cord-006870-f5w6fw6q 5728 1 CAS CAS NNP cord-006870-f5w6fw6q 5728 2 was be VBD cord-006870-f5w6fw6q 5728 3 uneventful uneventful JJ cord-006870-f5w6fw6q 5728 4 , , , cord-006870-f5w6fw6q 5728 5 but but CC cord-006870-f5w6fw6q 5728 6 the the DT cord-006870-f5w6fw6q 5728 7 following following JJ cord-006870-f5w6fw6q 5728 8 morning morning NN cord-006870-f5w6fw6q 5728 9 , , , cord-006870-f5w6fw6q 5728 10 the the DT cord-006870-f5w6fw6q 5728 11 patient patient NN cord-006870-f5w6fw6q 5728 12 developed develop VBD cord-006870-f5w6fw6q 5728 13 pain pain NN cord-006870-f5w6fw6q 5728 14 in in IN cord-006870-f5w6fw6q 5728 15 the the DT cord-006870-f5w6fw6q 5728 16 left left JJ cord-006870-f5w6fw6q 5728 17 eyeball eyeball NN cord-006870-f5w6fw6q 5728 18 with with IN cord-006870-f5w6fw6q 5728 19 an an DT cord-006870-f5w6fw6q 5728 20 IOP IOP NNP cord-006870-f5w6fw6q 5728 21 of of IN cord-006870-f5w6fw6q 5728 22 49 49 CD cord-006870-f5w6fw6q 5728 23 mm mm NN cord-006870-f5w6fw6q 5728 24 Hg Hg NNS cord-006870-f5w6fw6q 5728 25 . . . cord-006870-f5w6fw6q 5729 1 Anterior Anterior NNP cord-006870-f5w6fw6q 5729 2 chamber chamber NN cord-006870-f5w6fw6q 5729 3 paracentesis paracentesi NNS cord-006870-f5w6fw6q 5729 4 followed follow VBD cord-006870-f5w6fw6q 5729 5 by by IN cord-006870-f5w6fw6q 5729 6 intraocular intraocular JJ cord-006870-f5w6fw6q 5729 7 injection injection NN cord-006870-f5w6fw6q 5729 8 of of IN cord-006870-f5w6fw6q 5729 9 bevacizumab bevacizumab NNP cord-006870-f5w6fw6q 5729 10 , , , cord-006870-f5w6fw6q 5729 11 panretinal panretinal NNP cord-006870-f5w6fw6q 5729 12 photocoagulation photocoagulation NN cord-006870-f5w6fw6q 5729 13 , , , cord-006870-f5w6fw6q 5729 14 and and CC cord-006870-f5w6fw6q 5729 15 medical medical JJ cord-006870-f5w6fw6q 5729 16 treatment treatment NN cord-006870-f5w6fw6q 5729 17 failed fail VBD cord-006870-f5w6fw6q 5729 18 to to TO cord-006870-f5w6fw6q 5729 19 reduce reduce VB cord-006870-f5w6fw6q 5729 20 the the DT cord-006870-f5w6fw6q 5729 21 IOP IOP NNP cord-006870-f5w6fw6q 5729 22 below below IN cord-006870-f5w6fw6q 5729 23 32 32 CD cord-006870-f5w6fw6q 5729 24 - - SYM cord-006870-f5w6fw6q 5729 25 36 36 CD cord-006870-f5w6fw6q 5729 26 mm mm NN cord-006870-f5w6fw6q 5729 27 Hg Hg NNS cord-006870-f5w6fw6q 5729 28 . . . cord-006870-f5w6fw6q 5730 1 Eighteen eighteen CD cord-006870-f5w6fw6q 5730 2 days day NNS cord-006870-f5w6fw6q 5730 3 following follow VBG cord-006870-f5w6fw6q 5730 4 CAS CAS NNP cord-006870-f5w6fw6q 5730 5 , , , cord-006870-f5w6fw6q 5730 6 an an DT cord-006870-f5w6fw6q 5730 7 Ahmed Ahmed NNP cord-006870-f5w6fw6q 5730 8 glaucoma glaucoma NN cord-006870-f5w6fw6q 5730 9 valve valve NN cord-006870-f5w6fw6q 5730 10 was be VBD cord-006870-f5w6fw6q 5730 11 implanted implant VBN cord-006870-f5w6fw6q 5730 12 in in IN cord-006870-f5w6fw6q 5730 13 the the DT cord-006870-f5w6fw6q 5730 14 left left JJ cord-006870-f5w6fw6q 5730 15 eye eye NN cord-006870-f5w6fw6q 5730 16 to to TO cord-006870-f5w6fw6q 5730 17 treat treat VB cord-006870-f5w6fw6q 5730 18 the the DT cord-006870-f5w6fw6q 5730 19 refractory refractory JJ cord-006870-f5w6fw6q 5730 20 NVG NVG NNP cord-006870-f5w6fw6q 5730 21 . . . cord-006870-f5w6fw6q 5731 1 IOP IOP NNP cord-006870-f5w6fw6q 5731 2 decreased decrease VBD cord-006870-f5w6fw6q 5731 3 to to IN cord-006870-f5w6fw6q 5731 4 6 6 CD cord-006870-f5w6fw6q 5731 5 mmHg mmHg NNS cord-006870-f5w6fw6q 5731 6 and and CC cord-006870-f5w6fw6q 5731 7 his -PRON- PRP$ cord-006870-f5w6fw6q 5731 8 ocular ocular JJ cord-006870-f5w6fw6q 5731 9 pain pain NN cord-006870-f5w6fw6q 5731 10 resolved resolve VBN cord-006870-f5w6fw6q 5731 11 completely completely RB cord-006870-f5w6fw6q 5731 12 post post JJ cord-006870-f5w6fw6q 5731 13 implantation implantation NN cord-006870-f5w6fw6q 5731 14 . . . cord-006870-f5w6fw6q 5732 1 Although although IN cord-006870-f5w6fw6q 5732 2 NVG NVG NNP cord-006870-f5w6fw6q 5732 3 is be VBZ cord-006870-f5w6fw6q 5732 4 a a DT cord-006870-f5w6fw6q 5732 5 rare rare JJ cord-006870-f5w6fw6q 5732 6 complication complication NN cord-006870-f5w6fw6q 5732 7 of of IN cord-006870-f5w6fw6q 5732 8 CAS CAS NNP cord-006870-f5w6fw6q 5732 9 , , , cord-006870-f5w6fw6q 5732 10 it -PRON- PRP cord-006870-f5w6fw6q 5732 11 should should MD cord-006870-f5w6fw6q 5732 12 be be VB cord-006870-f5w6fw6q 5732 13 suspected suspect VBN cord-006870-f5w6fw6q 5732 14 in in IN cord-006870-f5w6fw6q 5732 15 patients patient NNS cord-006870-f5w6fw6q 5732 16 who who WP cord-006870-f5w6fw6q 5732 17 develop develop VBP cord-006870-f5w6fw6q 5732 18 acute acute JJ cord-006870-f5w6fw6q 5732 19 ocular ocular JJ cord-006870-f5w6fw6q 5732 20 pain pain NN cord-006870-f5w6fw6q 5732 21 following follow VBG cord-006870-f5w6fw6q 5732 22 CAS CAS NNP cord-006870-f5w6fw6q 5732 23 . . . cord-006870-f5w6fw6q 5733 1 NVG NVG NNP cord-006870-f5w6fw6q 5733 2 may may MD cord-006870-f5w6fw6q 5733 3 respond respond VB cord-006870-f5w6fw6q 5733 4 to to IN cord-006870-f5w6fw6q 5733 5 anterior anterior NNP cord-006870-f5w6fw6q 5733 6 chamber chamber NNP cord-006870-f5w6fw6q 5733 7 paracentesis paracentesis NNP cord-006870-f5w6fw6q 5733 8 , , , cord-006870-f5w6fw6q 5733 9 panretinal panretinal NNP cord-006870-f5w6fw6q 5733 10 photocoagulation photocoagulation NN cord-006870-f5w6fw6q 5733 11 , , , cord-006870-f5w6fw6q 5733 12 and and CC cord-006870-f5w6fw6q 5733 13 bevacizumab bevacizumab NNP cord-006870-f5w6fw6q 5733 14 , , , cord-006870-f5w6fw6q 5733 15 but but CC cord-006870-f5w6fw6q 5733 16 surgical surgical JJ cord-006870-f5w6fw6q 5733 17 treatment treatment NN cord-006870-f5w6fw6q 5733 18 , , , cord-006870-f5w6fw6q 5733 19 such such JJ cord-006870-f5w6fw6q 5733 20 as as IN cord-006870-f5w6fw6q 5733 21 implantation implantation NN cord-006870-f5w6fw6q 5733 22 of of IN cord-006870-f5w6fw6q 5733 23 an an DT cord-006870-f5w6fw6q 5733 24 Ahmed Ahmed NNP cord-006870-f5w6fw6q 5733 25 glaucoma glaucoma NN cord-006870-f5w6fw6q 5733 26 valve valve NN cord-006870-f5w6fw6q 5733 27 , , , cord-006870-f5w6fw6q 5733 28 should should MD cord-006870-f5w6fw6q 5733 29 be be VB cord-006870-f5w6fw6q 5733 30 considered consider VBN cord-006870-f5w6fw6q 5733 31 in in IN cord-006870-f5w6fw6q 5733 32 cases case NNS cord-006870-f5w6fw6q 5733 33 with with IN cord-006870-f5w6fw6q 5733 34 refractory refractory JJ cord-006870-f5w6fw6q 5733 35 NVG NVG NNP cord-006870-f5w6fw6q 5733 36 . . . cord-006870-f5w6fw6q 5734 1 Background background NN cord-006870-f5w6fw6q 5734 2 : : : cord-006870-f5w6fw6q 5735 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 5735 2 amyloid amyloid NN cord-006870-f5w6fw6q 5735 3 angiopathy angiopathy NNP cord-006870-f5w6fw6q 5735 4 is be VBZ cord-006870-f5w6fw6q 5735 5 a a DT cord-006870-f5w6fw6q 5735 6 common common JJ cord-006870-f5w6fw6q 5735 7 cause cause NN cord-006870-f5w6fw6q 5735 8 of of IN cord-006870-f5w6fw6q 5735 9 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5735 10 lobar lobar NN cord-006870-f5w6fw6q 5735 11 intracerebral intracerebral NNP cord-006870-f5w6fw6q 5735 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5735 13 . . . cord-006870-f5w6fw6q 5736 1 Convexal convexal NN cord-006870-f5w6fw6q 5736 2 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5736 3 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5736 4 can can MD cord-006870-f5w6fw6q 5736 5 be be VB cord-006870-f5w6fw6q 5736 6 a a DT cord-006870-f5w6fw6q 5736 7 manifestation manifestation NN cord-006870-f5w6fw6q 5736 8 of of IN cord-006870-f5w6fw6q 5736 9 cerebral cerebral JJ cord-006870-f5w6fw6q 5736 10 amyloid amyloid NN cord-006870-f5w6fw6q 5736 11 angiopathy angiopathy NNP cord-006870-f5w6fw6q 5736 12 . . . cord-006870-f5w6fw6q 5737 1 Whether whether IN cord-006870-f5w6fw6q 5737 2 focal focal JJ cord-006870-f5w6fw6q 5737 3 amyloid amyloid NN cord-006870-f5w6fw6q 5737 4 burden burden NN cord-006870-f5w6fw6q 5737 5 predicts predict VBZ cord-006870-f5w6fw6q 5737 6 future future JJ cord-006870-f5w6fw6q 5737 7 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5737 8 is be VBZ cord-006870-f5w6fw6q 5737 9 unclear unclear JJ cord-006870-f5w6fw6q 5737 10 . . . cord-006870-f5w6fw6q 5738 1 Case case NN cord-006870-f5w6fw6q 5738 2 : : : cord-006870-f5w6fw6q 5739 1 An an DT cord-006870-f5w6fw6q 5739 2 82-year 82-year JJ cord-006870-f5w6fw6q 5739 3 - - HYPH cord-006870-f5w6fw6q 5739 4 old old JJ cord-006870-f5w6fw6q 5739 5 man man NN cord-006870-f5w6fw6q 5739 6 presented present VBN cord-006870-f5w6fw6q 5739 7 with with IN cord-006870-f5w6fw6q 5739 8 transient transient JJ cord-006870-f5w6fw6q 5739 9 left left JJ cord-006870-f5w6fw6q 5739 10 arm arm NN cord-006870-f5w6fw6q 5739 11 weakness weakness NN cord-006870-f5w6fw6q 5739 12 and and CC cord-006870-f5w6fw6q 5739 13 paresthesias paresthesia NNS cord-006870-f5w6fw6q 5739 14 in in IN cord-006870-f5w6fw6q 5739 15 the the DT cord-006870-f5w6fw6q 5739 16 setting setting NN cord-006870-f5w6fw6q 5739 17 of of IN cord-006870-f5w6fw6q 5739 18 previous previous JJ cord-006870-f5w6fw6q 5739 19 cognitive cognitive JJ cord-006870-f5w6fw6q 5739 20 decline decline NN cord-006870-f5w6fw6q 5739 21 . . . cord-006870-f5w6fw6q 5740 1 MRI MRI NNP cord-006870-f5w6fw6q 5740 2 showed show VBD cord-006870-f5w6fw6q 5740 3 a a DT cord-006870-f5w6fw6q 5740 4 convexal convexal NN cord-006870-f5w6fw6q 5740 5 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5740 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5740 7 of of IN cord-006870-f5w6fw6q 5740 8 the the DT cord-006870-f5w6fw6q 5740 9 right right JJ cord-006870-f5w6fw6q 5740 10 central central JJ cord-006870-f5w6fw6q 5740 11 sulcus sulcus NN cord-006870-f5w6fw6q 5740 12 , , , cord-006870-f5w6fw6q 5740 13 as as RB cord-006870-f5w6fw6q 5740 14 well well RB cord-006870-f5w6fw6q 5740 15 as as IN cord-006870-f5w6fw6q 5740 16 susceptibility susceptibility NN cord-006870-f5w6fw6q 5740 17 weighted weight VBN cord-006870-f5w6fw6q 5740 18 imaging imaging NN cord-006870-f5w6fw6q 5740 19 findings finding NNS cord-006870-f5w6fw6q 5740 20 consistent consistent JJ cord-006870-f5w6fw6q 5740 21 with with IN cord-006870-f5w6fw6q 5740 22 superficial superficial JJ cord-006870-f5w6fw6q 5740 23 siderosis siderosis NN cord-006870-f5w6fw6q 5740 24 . . . cord-006870-f5w6fw6q 5741 1 Lumbar lumbar JJ cord-006870-f5w6fw6q 5741 2 puncture puncture NN cord-006870-f5w6fw6q 5741 3 revealed reveal VBD cord-006870-f5w6fw6q 5741 4 normal normal JJ cord-006870-f5w6fw6q 5741 5 cell cell NN cord-006870-f5w6fw6q 5741 6 count count NN cord-006870-f5w6fw6q 5741 7 with with IN cord-006870-f5w6fw6q 5741 8 a a DT cord-006870-f5w6fw6q 5741 9 mildly mildly RB cord-006870-f5w6fw6q 5741 10 elevated elevated JJ cord-006870-f5w6fw6q 5741 11 protein protein NN cord-006870-f5w6fw6q 5741 12 . . . cord-006870-f5w6fw6q 5742 1 He -PRON- PRP cord-006870-f5w6fw6q 5742 2 had have VBD cord-006870-f5w6fw6q 5742 3 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5742 4 resolution resolution NN cord-006870-f5w6fw6q 5742 5 of of IN cord-006870-f5w6fw6q 5742 6 his -PRON- PRP$ cord-006870-f5w6fw6q 5742 7 symptoms symptom NNS cord-006870-f5w6fw6q 5742 8 after after IN cord-006870-f5w6fw6q 5742 9 several several JJ cord-006870-f5w6fw6q 5742 10 hours hour NNS cord-006870-f5w6fw6q 5742 11 . . . cord-006870-f5w6fw6q 5743 1 One one CD cord-006870-f5w6fw6q 5743 2 year year NN cord-006870-f5w6fw6q 5743 3 later later RBR cord-006870-f5w6fw6q 5743 4 he -PRON- PRP cord-006870-f5w6fw6q 5743 5 presented present VBD cord-006870-f5w6fw6q 5743 6 with with IN cord-006870-f5w6fw6q 5743 7 sudden sudden JJ cord-006870-f5w6fw6q 5743 8 onset onset NN cord-006870-f5w6fw6q 5743 9 confusion confusion NN cord-006870-f5w6fw6q 5743 10 and and CC cord-006870-f5w6fw6q 5743 11 imaging imaging NN cord-006870-f5w6fw6q 5743 12 again again RB cord-006870-f5w6fw6q 5743 13 showed show VBD cord-006870-f5w6fw6q 5743 14 a a DT cord-006870-f5w6fw6q 5743 15 convexal convexal NN cord-006870-f5w6fw6q 5743 16 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5743 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5743 18 over over IN cord-006870-f5w6fw6q 5743 19 the the DT cord-006870-f5w6fw6q 5743 20 posterior posterior JJ cord-006870-f5w6fw6q 5743 21 right right JJ cord-006870-f5w6fw6q 5743 22 frontal frontal JJ cord-006870-f5w6fw6q 5743 23 lobe lobe NN cord-006870-f5w6fw6q 5743 24 . . . cord-006870-f5w6fw6q 5744 1 Susceptibility susceptibility NN cord-006870-f5w6fw6q 5744 2 weighted weight VBD cord-006870-f5w6fw6q 5744 3 MRI MRI NNP cord-006870-f5w6fw6q 5744 4 revealed reveal VBD cord-006870-f5w6fw6q 5744 5 hemosiderin hemosiderin NN cord-006870-f5w6fw6q 5744 6 over over IN cord-006870-f5w6fw6q 5744 7 the the DT cord-006870-f5w6fw6q 5744 8 right right JJ cord-006870-f5w6fw6q 5744 9 posterior posterior JJ cord-006870-f5w6fw6q 5744 10 frontal frontal JJ cord-006870-f5w6fw6q 5744 11 and and CC cord-006870-f5w6fw6q 5744 12 anterior anterior JJ cord-006870-f5w6fw6q 5744 13 parietal parietal JJ cord-006870-f5w6fw6q 5744 14 lobes lobe NNS cord-006870-f5w6fw6q 5744 15 . . . cord-006870-f5w6fw6q 5745 1 An an DT cord-006870-f5w6fw6q 5745 2 amyloid amyloid NN cord-006870-f5w6fw6q 5745 3 - - HYPH cord-006870-f5w6fw6q 5745 4 PET pet NN cord-006870-f5w6fw6q 5745 5 , , , cord-006870-f5w6fw6q 5745 6 obtained obtain VBD cord-006870-f5w6fw6q 5745 7 one one CD cord-006870-f5w6fw6q 5745 8 year year NN cord-006870-f5w6fw6q 5745 9 prior prior RB cord-006870-f5w6fw6q 5745 10 to to IN cord-006870-f5w6fw6q 5745 11 his -PRON- PRP$ cord-006870-f5w6fw6q 5745 12 first first JJ cord-006870-f5w6fw6q 5745 13 spell spell NN cord-006870-f5w6fw6q 5745 14 as as IN cord-006870-f5w6fw6q 5745 15 a a DT cord-006870-f5w6fw6q 5745 16 research research NN cord-006870-f5w6fw6q 5745 17 participant participant NN cord-006870-f5w6fw6q 5745 18 , , , cord-006870-f5w6fw6q 5745 19 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5745 20 asymmetric asymmetric JJ cord-006870-f5w6fw6q 5745 21 amyloid amyloid NN cord-006870-f5w6fw6q 5745 22 deposition deposition NN cord-006870-f5w6fw6q 5745 23 in in IN cord-006870-f5w6fw6q 5745 24 the the DT cord-006870-f5w6fw6q 5745 25 right right JJ cord-006870-f5w6fw6q 5745 26 temporo temporo NN cord-006870-f5w6fw6q 5745 27 - - HYPH cord-006870-f5w6fw6q 5745 28 parietal parietal JJ cord-006870-f5w6fw6q 5745 29 region region NN cord-006870-f5w6fw6q 5745 30 . . . cord-006870-f5w6fw6q 5746 1 6 6 CD cord-006870-f5w6fw6q 5746 2 years year NNS cord-006870-f5w6fw6q 5746 3 after after IN cord-006870-f5w6fw6q 5746 4 his -PRON- PRP$ cord-006870-f5w6fw6q 5746 5 initial initial JJ cord-006870-f5w6fw6q 5746 6 episode episode NN cord-006870-f5w6fw6q 5746 7 he -PRON- PRP cord-006870-f5w6fw6q 5746 8 presented present VBD cord-006870-f5w6fw6q 5746 9 again again RB cord-006870-f5w6fw6q 5746 10 with with IN cord-006870-f5w6fw6q 5746 11 confusion confusion NN cord-006870-f5w6fw6q 5746 12 , , , cord-006870-f5w6fw6q 5746 13 headache headache NN cord-006870-f5w6fw6q 5746 14 , , , cord-006870-f5w6fw6q 5746 15 and and CC cord-006870-f5w6fw6q 5746 16 decreased decrease VBD cord-006870-f5w6fw6q 5746 17 level level NN cord-006870-f5w6fw6q 5746 18 of of IN cord-006870-f5w6fw6q 5746 19 alertness alertness NN cord-006870-f5w6fw6q 5746 20 . . . cord-006870-f5w6fw6q 5747 1 A a DT cord-006870-f5w6fw6q 5747 2 CT CT NNP cord-006870-f5w6fw6q 5747 3 scan scan NN cord-006870-f5w6fw6q 5747 4 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5747 5 a a DT cord-006870-f5w6fw6q 5747 6 right right JJ cord-006870-f5w6fw6q 5747 7 - - HYPH cord-006870-f5w6fw6q 5747 8 sided sided JJ cord-006870-f5w6fw6q 5747 9 temporo temporo NNS cord-006870-f5w6fw6q 5747 10 - - HYPH cord-006870-f5w6fw6q 5747 11 parietal parietal JJ cord-006870-f5w6fw6q 5747 12 intracerebral intracerebral JJ cord-006870-f5w6fw6q 5747 13 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5747 14 in in IN cord-006870-f5w6fw6q 5747 15 the the DT cord-006870-f5w6fw6q 5747 16 area area NN cord-006870-f5w6fw6q 5747 17 of of IN cord-006870-f5w6fw6q 5747 18 asymmetric asymmetric JJ cord-006870-f5w6fw6q 5747 19 amyloid amyloid NN cord-006870-f5w6fw6q 5747 20 deposition deposition NN cord-006870-f5w6fw6q 5747 21 on on IN cord-006870-f5w6fw6q 5747 22 PET PET NNP cord-006870-f5w6fw6q 5747 23 . . . cord-006870-f5w6fw6q 5748 1 His -PRON- PRP$ cord-006870-f5w6fw6q 5748 2 family family NN cord-006870-f5w6fw6q 5748 3 opted opt VBD cord-006870-f5w6fw6q 5748 4 for for IN cord-006870-f5w6fw6q 5748 5 comfort comfort NN cord-006870-f5w6fw6q 5748 6 measures measure NNS cord-006870-f5w6fw6q 5748 7 only only RB cord-006870-f5w6fw6q 5748 8 , , , cord-006870-f5w6fw6q 5748 9 and and CC cord-006870-f5w6fw6q 5748 10 he -PRON- PRP cord-006870-f5w6fw6q 5748 11 was be VBD cord-006870-f5w6fw6q 5748 12 discharged discharge VBN cord-006870-f5w6fw6q 5748 13 to to IN cord-006870-f5w6fw6q 5748 14 hospice hospice NN cord-006870-f5w6fw6q 5748 15 . . . cord-006870-f5w6fw6q 5749 1 Autopsy Autopsy NNP cord-006870-f5w6fw6q 5749 2 revealed reveal VBD cord-006870-f5w6fw6q 5749 3 severe severe JJ cord-006870-f5w6fw6q 5749 4 amyloid amyloid NN cord-006870-f5w6fw6q 5749 5 angiopathy angiopathy NNP cord-006870-f5w6fw6q 5749 6 , , , cord-006870-f5w6fw6q 5749 7 as as RB cord-006870-f5w6fw6q 5749 8 well well RB cord-006870-f5w6fw6q 5749 9 as as IN cord-006870-f5w6fw6q 5749 10 Alzheimer Alzheimer NNP cord-006870-f5w6fw6q 5749 11 disease disease NN cord-006870-f5w6fw6q 5749 12 , , , cord-006870-f5w6fw6q 5749 13 Braak Braak NNP cord-006870-f5w6fw6q 5749 14 stage stage NN cord-006870-f5w6fw6q 5749 15 VI VI NNP cord-006870-f5w6fw6q 5749 16 . . . cord-006870-f5w6fw6q 5750 1 Discussion discussion NN cord-006870-f5w6fw6q 5750 2 : : : cord-006870-f5w6fw6q 5751 1 This this DT cord-006870-f5w6fw6q 5751 2 case case NN cord-006870-f5w6fw6q 5751 3 illustrates illustrate VBZ cord-006870-f5w6fw6q 5751 4 the the DT cord-006870-f5w6fw6q 5751 5 clinical clinical JJ cord-006870-f5w6fw6q 5751 6 course course NN cord-006870-f5w6fw6q 5751 7 of of IN cord-006870-f5w6fw6q 5751 8 a a DT cord-006870-f5w6fw6q 5751 9 patient patient NN cord-006870-f5w6fw6q 5751 10 with with IN cord-006870-f5w6fw6q 5751 11 amyloid amyloid NN cord-006870-f5w6fw6q 5751 12 angiopathy angiopathy NNP cord-006870-f5w6fw6q 5751 13 , , , cord-006870-f5w6fw6q 5751 14 including include VBG cord-006870-f5w6fw6q 5751 15 recurrent recurrent JJ cord-006870-f5w6fw6q 5751 16 convexal convexal NN cord-006870-f5w6fw6q 5751 17 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5751 18 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 5751 19 , , , cord-006870-f5w6fw6q 5751 20 and and CC cord-006870-f5w6fw6q 5751 21 superficial superficial JJ cord-006870-f5w6fw6q 5751 22 siderosis siderosis NN cord-006870-f5w6fw6q 5751 23 . . . cord-006870-f5w6fw6q 5752 1 Of of IN cord-006870-f5w6fw6q 5752 2 importance importance NN cord-006870-f5w6fw6q 5752 3 , , , cord-006870-f5w6fw6q 5752 4 the the DT cord-006870-f5w6fw6q 5752 5 amyloid amyloid NN cord-006870-f5w6fw6q 5752 6 PET pet NN cord-006870-f5w6fw6q 5752 7 scan scan NN cord-006870-f5w6fw6q 5752 8 predicted predict VBD cord-006870-f5w6fw6q 5752 9 the the DT cord-006870-f5w6fw6q 5752 10 location location NN cord-006870-f5w6fw6q 5752 11 of of IN cord-006870-f5w6fw6q 5752 12 his -PRON- PRP$ cord-006870-f5w6fw6q 5752 13 intracerebral intracerebral JJ cord-006870-f5w6fw6q 5752 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5752 15 7 7 CD cord-006870-f5w6fw6q 5752 16 years year NNS cord-006870-f5w6fw6q 5752 17 later later RB cord-006870-f5w6fw6q 5752 18 . . . cord-006870-f5w6fw6q 5753 1 The the DT cord-006870-f5w6fw6q 5753 2 case case NN cord-006870-f5w6fw6q 5753 3 of of IN cord-006870-f5w6fw6q 5753 4 a a DT cord-006870-f5w6fw6q 5753 5 23-year 23-year JJ cord-006870-f5w6fw6q 5753 6 - - HYPH cord-006870-f5w6fw6q 5753 7 old old JJ cord-006870-f5w6fw6q 5753 8 man man NN cord-006870-f5w6fw6q 5753 9 , , , cord-006870-f5w6fw6q 5753 10 presenting present VBG cord-006870-f5w6fw6q 5753 11 with with IN cord-006870-f5w6fw6q 5753 12 a a DT cord-006870-f5w6fw6q 5753 13 past past JJ cord-006870-f5w6fw6q 5753 14 medical medical JJ cord-006870-f5w6fw6q 5753 15 history history NN cord-006870-f5w6fw6q 5753 16 of of IN cord-006870-f5w6fw6q 5753 17 migraine migraine NN cord-006870-f5w6fw6q 5753 18 headaches headache NNS cord-006870-f5w6fw6q 5753 19 , , , cord-006870-f5w6fw6q 5753 20 dipola dipola NNP cord-006870-f5w6fw6q 5753 21 , , , cord-006870-f5w6fw6q 5753 22 vertigo vertigo NNP cord-006870-f5w6fw6q 5753 23 , , , cord-006870-f5w6fw6q 5753 24 with with IN cord-006870-f5w6fw6q 5753 25 symptoms symptom NNS cord-006870-f5w6fw6q 5753 26 later later RB cord-006870-f5w6fw6q 5753 27 progressing progress VBG cord-006870-f5w6fw6q 5753 28 to to IN cord-006870-f5w6fw6q 5753 29 lethargy lethargy NN cord-006870-f5w6fw6q 5753 30 and and CC cord-006870-f5w6fw6q 5753 31 confusion confusion NN cord-006870-f5w6fw6q 5753 32 for for IN cord-006870-f5w6fw6q 5753 33 10 10 CD cord-006870-f5w6fw6q 5753 34 days day NNS cord-006870-f5w6fw6q 5753 35 . . . cord-006870-f5w6fw6q 5754 1 Brain Brain NNP cord-006870-f5w6fw6q 5754 2 MRI MRI NNP cord-006870-f5w6fw6q 5754 3 revealed reveal VBD cord-006870-f5w6fw6q 5754 4 a a DT cord-006870-f5w6fw6q 5754 5 peripherally peripherally RB cord-006870-f5w6fw6q 5754 6 enhancing enhance VBG cord-006870-f5w6fw6q 5754 7 mass mass NN cord-006870-f5w6fw6q 5754 8 within within IN cord-006870-f5w6fw6q 5754 9 the the DT cord-006870-f5w6fw6q 5754 10 left left JJ cord-006870-f5w6fw6q 5754 11 thalamus thalamus NN cord-006870-f5w6fw6q 5754 12 with with IN cord-006870-f5w6fw6q 5754 13 central central JJ cord-006870-f5w6fw6q 5754 14 restricted restricted JJ cord-006870-f5w6fw6q 5754 15 diffusion diffusion NN cord-006870-f5w6fw6q 5754 16 , , , cord-006870-f5w6fw6q 5754 17 which which WDT cord-006870-f5w6fw6q 5754 18 is be VBZ cord-006870-f5w6fw6q 5754 19 consistent consistent JJ cord-006870-f5w6fw6q 5754 20 with with IN cord-006870-f5w6fw6q 5754 21 a a DT cord-006870-f5w6fw6q 5754 22 cerebral cerebral JJ cord-006870-f5w6fw6q 5754 23 abscess abscess NN cord-006870-f5w6fw6q 5754 24 . . . cord-006870-f5w6fw6q 5755 1 Case case NN cord-006870-f5w6fw6q 5755 2 report report NN cord-006870-f5w6fw6q 5755 3 of of IN cord-006870-f5w6fw6q 5755 4 congenital congenital JJ cord-006870-f5w6fw6q 5755 5 heart heart NN cord-006870-f5w6fw6q 5755 6 disease disease NN cord-006870-f5w6fw6q 5755 7 when when WRB cord-006870-f5w6fw6q 5755 8 discovered discover VBN cord-006870-f5w6fw6q 5755 9 in in IN cord-006870-f5w6fw6q 5755 10 adulthood adulthood NN cord-006870-f5w6fw6q 5755 11 is be VBZ cord-006870-f5w6fw6q 5755 12 an an DT cord-006870-f5w6fw6q 5755 13 interesting interesting JJ cord-006870-f5w6fw6q 5755 14 entity entity NN cord-006870-f5w6fw6q 5755 15 , , , cord-006870-f5w6fw6q 5755 16 especially especially RB cord-006870-f5w6fw6q 5755 17 when when WRB cord-006870-f5w6fw6q 5755 18 it -PRON- PRP cord-006870-f5w6fw6q 5755 19 is be VBZ cord-006870-f5w6fw6q 5755 20 the the DT cord-006870-f5w6fw6q 5755 21 source source NN cord-006870-f5w6fw6q 5755 22 of of IN cord-006870-f5w6fw6q 5755 23 brain brain NN cord-006870-f5w6fw6q 5755 24 abscesses abscess NNS cord-006870-f5w6fw6q 5755 25 . . . cord-006870-f5w6fw6q 5756 1 Detailed detailed JJ cord-006870-f5w6fw6q 5756 2 history history NN cord-006870-f5w6fw6q 5756 3 taking take VBG cord-006870-f5w6fw6q 5756 4 , , , cord-006870-f5w6fw6q 5756 5 physical physical JJ cord-006870-f5w6fw6q 5756 6 examination examination NN cord-006870-f5w6fw6q 5756 7 and and CC cord-006870-f5w6fw6q 5756 8 appropriate appropriate JJ cord-006870-f5w6fw6q 5756 9 imaging imaging NN cord-006870-f5w6fw6q 5756 10 can can MD cord-006870-f5w6fw6q 5756 11 usually usually RB cord-006870-f5w6fw6q 5756 12 reveal reveal VB cord-006870-f5w6fw6q 5756 13 the the DT cord-006870-f5w6fw6q 5756 14 anomaly anomaly NN cord-006870-f5w6fw6q 5756 15 . . . cord-006870-f5w6fw6q 5757 1 The the DT cord-006870-f5w6fw6q 5757 2 diagnosis diagnosis NN cord-006870-f5w6fw6q 5757 3 of of IN cord-006870-f5w6fw6q 5757 4 brain brain NN cord-006870-f5w6fw6q 5757 5 abscess abscess NN cord-006870-f5w6fw6q 5757 6 should should MD cord-006870-f5w6fw6q 5757 7 promote promote VB cord-006870-f5w6fw6q 5757 8 the the DT cord-006870-f5w6fw6q 5757 9 clinician clinician NN cord-006870-f5w6fw6q 5757 10 to to TO cord-006870-f5w6fw6q 5757 11 consider consider VB cord-006870-f5w6fw6q 5757 12 right right JJ cord-006870-f5w6fw6q 5757 13 to to IN cord-006870-f5w6fw6q 5757 14 left leave VBN cord-006870-f5w6fw6q 5757 15 shunts shunt NNS cord-006870-f5w6fw6q 5757 16 as as IN cord-006870-f5w6fw6q 5757 17 a a DT cord-006870-f5w6fw6q 5757 18 possible possible JJ cord-006870-f5w6fw6q 5757 19 predisposing predisposing JJ cord-006870-f5w6fw6q 5757 20 condition condition NN cord-006870-f5w6fw6q 5757 21 for for IN cord-006870-f5w6fw6q 5757 22 brain brain NN cord-006870-f5w6fw6q 5757 23 abscess abscess NN cord-006870-f5w6fw6q 5757 24 Management Management NNP cord-006870-f5w6fw6q 5757 25 of of IN cord-006870-f5w6fw6q 5757 26 acute acute JJ cord-006870-f5w6fw6q 5757 27 cerebral cerebral JJ cord-006870-f5w6fw6q 5757 28 embolism embolism NN cord-006870-f5w6fw6q 5757 29 in in IN cord-006870-f5w6fw6q 5757 30 patients patient NNS cord-006870-f5w6fw6q 5757 31 with with IN cord-006870-f5w6fw6q 5757 32 implanted implant VBN cord-006870-f5w6fw6q 5757 33 ventricular ventricular JJ cord-006870-f5w6fw6q 5757 34 assist assist VB cord-006870-f5w6fw6q 5757 35 devices device NNS cord-006870-f5w6fw6q 5757 36 ( ( -LRB- cord-006870-f5w6fw6q 5757 37 VADs vad NNS cord-006870-f5w6fw6q 5757 38 ) ) -RRB- cord-006870-f5w6fw6q 5757 39 is be VBZ cord-006870-f5w6fw6q 5757 40 particularly particularly RB cord-006870-f5w6fw6q 5757 41 challenging challenging JJ cord-006870-f5w6fw6q 5757 42 , , , cord-006870-f5w6fw6q 5757 43 since since IN cord-006870-f5w6fw6q 5757 44 chronic chronic JJ cord-006870-f5w6fw6q 5757 45 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5757 46 often often RB cord-006870-f5w6fw6q 5757 47 precludes preclude VBZ cord-006870-f5w6fw6q 5757 48 the the DT cord-006870-f5w6fw6q 5757 49 use use NN cord-006870-f5w6fw6q 5757 50 of of IN cord-006870-f5w6fw6q 5757 51 intravenous intravenous JJ cord-006870-f5w6fw6q 5757 52 tissue tissue NN cord-006870-f5w6fw6q 5757 53 plasminogen plasminogen NN cord-006870-f5w6fw6q 5757 54 activator activator NN cord-006870-f5w6fw6q 5757 55 ( ( -LRB- cord-006870-f5w6fw6q 5757 56 IV IV NNP cord-006870-f5w6fw6q 5757 57 - - HYPH cord-006870-f5w6fw6q 5757 58 tPA tPA NNP cord-006870-f5w6fw6q 5757 59 ) ) -RRB- cord-006870-f5w6fw6q 5757 60 . . . cord-006870-f5w6fw6q 5758 1 We -PRON- PRP cord-006870-f5w6fw6q 5758 2 describe describe VBP cord-006870-f5w6fw6q 5758 3 a a DT cord-006870-f5w6fw6q 5758 4 VAD VAD NNP cord-006870-f5w6fw6q 5758 5 patient patient NN cord-006870-f5w6fw6q 5758 6 who who WP cord-006870-f5w6fw6q 5758 7 suffered suffer VBD cord-006870-f5w6fw6q 5758 8 cerebral cerebral JJ cord-006870-f5w6fw6q 5758 9 embolization embolization NN cord-006870-f5w6fw6q 5758 10 , , , cord-006870-f5w6fw6q 5758 11 and and CC cord-006870-f5w6fw6q 5758 12 was be VBD cord-006870-f5w6fw6q 5758 13 successfully successfully RB cord-006870-f5w6fw6q 5758 14 treated treat VBN cord-006870-f5w6fw6q 5758 15 with with IN cord-006870-f5w6fw6q 5758 16 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 5758 17 , , , cord-006870-f5w6fw6q 5758 18 emphasizing emphasize VBG cord-006870-f5w6fw6q 5758 19 the the DT cord-006870-f5w6fw6q 5758 20 nuances nuance NNS cord-006870-f5w6fw6q 5758 21 particular particular JJ cord-006870-f5w6fw6q 5758 22 to to IN cord-006870-f5w6fw6q 5758 23 this this DT cord-006870-f5w6fw6q 5758 24 clinical clinical JJ cord-006870-f5w6fw6q 5758 25 scenario scenario NN cord-006870-f5w6fw6q 5758 26 in in IN cord-006870-f5w6fw6q 5758 27 the the DT cord-006870-f5w6fw6q 5758 28 context context NN cord-006870-f5w6fw6q 5758 29 of of IN cord-006870-f5w6fw6q 5758 30 limited limited JJ cord-006870-f5w6fw6q 5758 31 historical historical JJ cord-006870-f5w6fw6q 5758 32 experience experience NN cord-006870-f5w6fw6q 5758 33 . . . cord-006870-f5w6fw6q 5759 1 A a DT cord-006870-f5w6fw6q 5759 2 54 54 CD cord-006870-f5w6fw6q 5759 3 year year NN cord-006870-f5w6fw6q 5759 4 - - HYPH cord-006870-f5w6fw6q 5759 5 old old JJ cord-006870-f5w6fw6q 5759 6 man man NN cord-006870-f5w6fw6q 5759 7 with with IN cord-006870-f5w6fw6q 5759 8 heart heart NN cord-006870-f5w6fw6q 5759 9 failure failure NN cord-006870-f5w6fw6q 5759 10 ( ( -LRB- cord-006870-f5w6fw6q 5759 11 ejection ejection NN cord-006870-f5w6fw6q 5759 12 fraction fraction NN cord-006870-f5w6fw6q 5759 13 10 10 CD cord-006870-f5w6fw6q 5759 14 % % NN cord-006870-f5w6fw6q 5759 15 ) ) -RRB- cord-006870-f5w6fw6q 5759 16 and and CC cord-006870-f5w6fw6q 5759 17 HeartWare HeartWare NNP cord-006870-f5w6fw6q 5759 18 II II NNP cord-006870-f5w6fw6q 5759 19 VAD VAD NNP cord-006870-f5w6fw6q 5759 20 implantation implantation NN cord-006870-f5w6fw6q 5759 21 about about IN cord-006870-f5w6fw6q 5759 22 15 15 CD cord-006870-f5w6fw6q 5759 23 months month NNS cord-006870-f5w6fw6q 5759 24 prior prior RB cord-006870-f5w6fw6q 5759 25 , , , cord-006870-f5w6fw6q 5759 26 was be VBD cord-006870-f5w6fw6q 5759 27 found find VBN cord-006870-f5w6fw6q 5759 28 at at IN cord-006870-f5w6fw6q 5759 29 the the DT cord-006870-f5w6fw6q 5759 30 scene scene NN cord-006870-f5w6fw6q 5759 31 of of IN cord-006870-f5w6fw6q 5759 32 a a DT cord-006870-f5w6fw6q 5759 33 car car NN cord-006870-f5w6fw6q 5759 34 accident accident NN cord-006870-f5w6fw6q 5759 35 with with IN cord-006870-f5w6fw6q 5759 36 expressive expressive JJ cord-006870-f5w6fw6q 5759 37 aphasia aphasia NNP cord-006870-f5w6fw6q 5759 38 , , , cord-006870-f5w6fw6q 5759 39 right right JJ cord-006870-f5w6fw6q 5759 40 homonymous homonymous JJ cord-006870-f5w6fw6q 5759 41 hemianopia hemianopia NN cord-006870-f5w6fw6q 5759 42 , , , cord-006870-f5w6fw6q 5759 43 extinction extinction NN cord-006870-f5w6fw6q 5759 44 and and CC cord-006870-f5w6fw6q 5759 45 right right JJ cord-006870-f5w6fw6q 5759 46 hemiplegia hemiplegia NN cord-006870-f5w6fw6q 5759 47 , , , cord-006870-f5w6fw6q 5759 48 with with IN cord-006870-f5w6fw6q 5759 49 a a DT cord-006870-f5w6fw6q 5759 50 National National NNP cord-006870-f5w6fw6q 5759 51 Institutes Institutes NNPS cord-006870-f5w6fw6q 5759 52 of of IN cord-006870-f5w6fw6q 5759 53 Health Health NNP cord-006870-f5w6fw6q 5759 54 Stroke Stroke NNP cord-006870-f5w6fw6q 5759 55 Scale Scale NNP cord-006870-f5w6fw6q 5759 56 ( ( -LRB- cord-006870-f5w6fw6q 5759 57 NIHSS NIHSS NNP cord-006870-f5w6fw6q 5759 58 ) ) -RRB- cord-006870-f5w6fw6q 5759 59 score score NN cord-006870-f5w6fw6q 5759 60 of of IN cord-006870-f5w6fw6q 5759 61 12 12 CD cord-006870-f5w6fw6q 5759 62 . . . cord-006870-f5w6fw6q 5760 1 Upon upon IN cord-006870-f5w6fw6q 5760 2 arrival arrival NN cord-006870-f5w6fw6q 5760 3 , , , cord-006870-f5w6fw6q 5760 4 his -PRON- PRP$ cord-006870-f5w6fw6q 5760 5 CT CT NNP cord-006870-f5w6fw6q 5760 6 was be VBD cord-006870-f5w6fw6q 5760 7 unremarkable unremarkable JJ cord-006870-f5w6fw6q 5760 8 , , , cord-006870-f5w6fw6q 5760 9 but but CC cord-006870-f5w6fw6q 5760 10 CTA CTA NNP cord-006870-f5w6fw6q 5760 11 revealed reveal VBD cord-006870-f5w6fw6q 5760 12 occlusion occlusion NN cord-006870-f5w6fw6q 5760 13 of of IN cord-006870-f5w6fw6q 5760 14 the the DT cord-006870-f5w6fw6q 5760 15 left left JJ cord-006870-f5w6fw6q 5760 16 middle middle JJ cord-006870-f5w6fw6q 5760 17 cerebral cerebral JJ cord-006870-f5w6fw6q 5760 18 artery artery NN cord-006870-f5w6fw6q 5760 19 ( ( -LRB- cord-006870-f5w6fw6q 5760 20 M1 M1 NNP cord-006870-f5w6fw6q 5760 21 segment segment NN cord-006870-f5w6fw6q 5760 22 ) ) -RRB- cord-006870-f5w6fw6q 5760 23 . . . cord-006870-f5w6fw6q 5761 1 Since since IN cord-006870-f5w6fw6q 5761 2 his -PRON- PRP$ cord-006870-f5w6fw6q 5761 3 INR INR NNP cord-006870-f5w6fw6q 5761 4 was be VBD cord-006870-f5w6fw6q 5761 5 2.1 2.1 CD cord-006870-f5w6fw6q 5761 6 , , , cord-006870-f5w6fw6q 5761 7 he -PRON- PRP cord-006870-f5w6fw6q 5761 8 underwent undergo VBD cord-006870-f5w6fw6q 5761 9 emergent emergent JJ cord-006870-f5w6fw6q 5761 10 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 5761 11 with with IN cord-006870-f5w6fw6q 5761 12 the the DT cord-006870-f5w6fw6q 5761 13 Solitaire Solitaire NNP cord-006870-f5w6fw6q 5761 14 device device NN cord-006870-f5w6fw6q 5761 15 , , , cord-006870-f5w6fw6q 5761 16 resulting result VBG cord-006870-f5w6fw6q 5761 17 in in IN cord-006870-f5w6fw6q 5761 18 complete complete JJ cord-006870-f5w6fw6q 5761 19 revascularization revascularization NN cord-006870-f5w6fw6q 5761 20 ( ( -LRB- cord-006870-f5w6fw6q 5761 21 TICI TICI NNP cord-006870-f5w6fw6q 5761 22 = = SYM cord-006870-f5w6fw6q 5761 23 3 3 CD cord-006870-f5w6fw6q 5761 24 ) ) -RRB- cord-006870-f5w6fw6q 5761 25 120 120 CD cord-006870-f5w6fw6q 5761 26 minutes minute NNS cord-006870-f5w6fw6q 5761 27 from from IN cord-006870-f5w6fw6q 5761 28 onset onset NN cord-006870-f5w6fw6q 5761 29 , , , cord-006870-f5w6fw6q 5761 30 with with IN cord-006870-f5w6fw6q 5761 31 rapid rapid JJ cord-006870-f5w6fw6q 5761 32 deficit deficit NN cord-006870-f5w6fw6q 5761 33 resolution resolution NN cord-006870-f5w6fw6q 5761 34 ( ( -LRB- cord-006870-f5w6fw6q 5761 35 NIHSS NIHSS NNP cord-006870-f5w6fw6q 5761 36 = = SYM cord-006870-f5w6fw6q 5761 37 0 0 CD cord-006870-f5w6fw6q 5761 38 ) ) -RRB- cord-006870-f5w6fw6q 5761 39 . . . cord-006870-f5w6fw6q 5762 1 The the DT cord-006870-f5w6fw6q 5762 2 procedural procedural JJ cord-006870-f5w6fw6q 5762 3 and and CC cord-006870-f5w6fw6q 5762 4 clinical clinical JJ cord-006870-f5w6fw6q 5762 5 success success NN cord-006870-f5w6fw6q 5762 6 was be VBD cord-006870-f5w6fw6q 5762 7 accompanied accompany VBN cord-006870-f5w6fw6q 5762 8 by by IN cord-006870-f5w6fw6q 5762 9 lack lack NN cord-006870-f5w6fw6q 5762 10 of of IN cord-006870-f5w6fw6q 5762 11 evidence evidence NN cord-006870-f5w6fw6q 5762 12 of of IN cord-006870-f5w6fw6q 5762 13 infarction infarction NN cord-006870-f5w6fw6q 5762 14 in in IN cord-006870-f5w6fw6q 5762 15 subsequent subsequent JJ cord-006870-f5w6fw6q 5762 16 CT CT NNP cord-006870-f5w6fw6q 5762 17 studies study NNS cord-006870-f5w6fw6q 5762 18 , , , cord-006870-f5w6fw6q 5762 19 and and CC cord-006870-f5w6fw6q 5762 20 a a DT cord-006870-f5w6fw6q 5762 21 modified modify VBN cord-006870-f5w6fw6q 5762 22 Rankin Rankin NNP cord-006870-f5w6fw6q 5762 23 score score NN cord-006870-f5w6fw6q 5762 24 of of IN cord-006870-f5w6fw6q 5762 25 0 0 CD cord-006870-f5w6fw6q 5762 26 upon upon IN cord-006870-f5w6fw6q 5762 27 discharge discharge NN cord-006870-f5w6fw6q 5762 28 . . . cord-006870-f5w6fw6q 5763 1 The the DT cord-006870-f5w6fw6q 5763 2 removed remove VBN cord-006870-f5w6fw6q 5763 3 thrombus thrombus NN cord-006870-f5w6fw6q 5763 4 displayed display VBD cord-006870-f5w6fw6q 5763 5 early early JJ cord-006870-f5w6fw6q 5763 6 organization organization NN cord-006870-f5w6fw6q 5763 7 , , , cord-006870-f5w6fw6q 5763 8 suggesting suggest VBG cord-006870-f5w6fw6q 5763 9 unexpected unexpected JJ cord-006870-f5w6fw6q 5763 10 firmness firmness NN cord-006870-f5w6fw6q 5763 11 , , , cord-006870-f5w6fw6q 5763 12 and and CC cord-006870-f5w6fw6q 5763 13 underscoring underscore VBG cord-006870-f5w6fw6q 5763 14 the the DT cord-006870-f5w6fw6q 5763 15 potential potential JJ cord-006870-f5w6fw6q 5763 16 importance importance NN cord-006870-f5w6fw6q 5763 17 of of IN cord-006870-f5w6fw6q 5763 18 mechanical mechanical JJ cord-006870-f5w6fw6q 5763 19 removal removal NN cord-006870-f5w6fw6q 5763 20 rather rather RB cord-006870-f5w6fw6q 5763 21 than than IN cord-006870-f5w6fw6q 5763 22 chemical chemical JJ cord-006870-f5w6fw6q 5763 23 lysis lysis NN cord-006870-f5w6fw6q 5763 24 in in IN cord-006870-f5w6fw6q 5763 25 VAD VAD NNP cord-006870-f5w6fw6q 5763 26 patients patient NNS cord-006870-f5w6fw6q 5763 27 . . . cord-006870-f5w6fw6q 5764 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5764 2 case case NN cord-006870-f5w6fw6q 5764 3 has have VBZ cord-006870-f5w6fw6q 5764 4 attributes attribute NNS cord-006870-f5w6fw6q 5764 5 that that WDT cord-006870-f5w6fw6q 5764 6 set set VBD cord-006870-f5w6fw6q 5764 7 it -PRON- PRP cord-006870-f5w6fw6q 5764 8 apart apart RB cord-006870-f5w6fw6q 5764 9 from from IN cord-006870-f5w6fw6q 5764 10 those those DT cord-006870-f5w6fw6q 5764 11 previously previously RB cord-006870-f5w6fw6q 5764 12 reported report VBN cord-006870-f5w6fw6q 5764 13 : : : cord-006870-f5w6fw6q 5765 1 1 1 LS cord-006870-f5w6fw6q 5765 2 ) ) -RRB- cord-006870-f5w6fw6q 5766 1 The the DT cord-006870-f5w6fw6q 5766 2 use use NN cord-006870-f5w6fw6q 5766 3 of of IN cord-006870-f5w6fw6q 5766 4 a a DT cord-006870-f5w6fw6q 5766 5 hybrid hybrid NN cord-006870-f5w6fw6q 5766 6 ( ( -LRB- cord-006870-f5w6fw6q 5766 7 i.e. i.e. FW cord-006870-f5w6fw6q 5766 8 retrieval retrieval NN cord-006870-f5w6fw6q 5766 9 PLUS plus CC cord-006870-f5w6fw6q 5766 10 aspiration aspiration NN cord-006870-f5w6fw6q 5766 11 ) ) -RRB- cord-006870-f5w6fw6q 5766 12 endovascular endovascular JJ cord-006870-f5w6fw6q 5766 13 retrieval retrieval NN cord-006870-f5w6fw6q 5766 14 technique technique NN cord-006870-f5w6fw6q 5766 15 , , , cord-006870-f5w6fw6q 5766 16 2 2 CD cord-006870-f5w6fw6q 5766 17 ) ) -RRB- cord-006870-f5w6fw6q 5767 1 The the DT cord-006870-f5w6fw6q 5767 2 lack lack NN cord-006870-f5w6fw6q 5767 3 of of IN cord-006870-f5w6fw6q 5767 4 concurrent concurrent JJ cord-006870-f5w6fw6q 5767 5 use use NN cord-006870-f5w6fw6q 5767 6 of of IN cord-006870-f5w6fw6q 5767 7 thrombolytic thrombolytic JJ cord-006870-f5w6fw6q 5767 8 drugs drug NNS cord-006870-f5w6fw6q 5767 9 , , , cord-006870-f5w6fw6q 5767 10 and and CC cord-006870-f5w6fw6q 5767 11 3 3 LS cord-006870-f5w6fw6q 5767 12 ) ) -RRB- cord-006870-f5w6fw6q 5768 1 The the DT cord-006870-f5w6fw6q 5768 2 rapid rapid JJ cord-006870-f5w6fw6q 5768 3 , , , cord-006870-f5w6fw6q 5768 4 sustained sustained JJ cord-006870-f5w6fw6q 5768 5 and and CC cord-006870-f5w6fw6q 5768 6 optimal optimal JJ cord-006870-f5w6fw6q 5768 7 clinical clinical JJ cord-006870-f5w6fw6q 5768 8 improvement improvement NN cord-006870-f5w6fw6q 5768 9 . . . cord-006870-f5w6fw6q 5769 1 The the DT cord-006870-f5w6fw6q 5769 2 utilization utilization NN cord-006870-f5w6fw6q 5769 3 of of IN cord-006870-f5w6fw6q 5769 4 VADs vad NNS cord-006870-f5w6fw6q 5769 5 continues continue VBZ cord-006870-f5w6fw6q 5769 6 to to TO cord-006870-f5w6fw6q 5769 7 grow grow VB cord-006870-f5w6fw6q 5769 8 , , , cord-006870-f5w6fw6q 5769 9 yet yet CC cord-006870-f5w6fw6q 5769 10 the the DT cord-006870-f5w6fw6q 5769 11 literature literature NN cord-006870-f5w6fw6q 5769 12 regarding regard VBG cord-006870-f5w6fw6q 5769 13 endovascular endovascular JJ cord-006870-f5w6fw6q 5769 14 techniques technique NNS cord-006870-f5w6fw6q 5769 15 for for IN cord-006870-f5w6fw6q 5769 16 managing manage VBG cord-006870-f5w6fw6q 5769 17 these these DT cord-006870-f5w6fw6q 5769 18 types type NNS cord-006870-f5w6fw6q 5769 19 of of IN cord-006870-f5w6fw6q 5769 20 patients patient NNS cord-006870-f5w6fw6q 5769 21 remain remain VBP cord-006870-f5w6fw6q 5769 22 scarce scarce JJ cord-006870-f5w6fw6q 5769 23 . . . cord-006870-f5w6fw6q 5770 1 However however RB cord-006870-f5w6fw6q 5770 2 , , , cord-006870-f5w6fw6q 5770 3 the the DT cord-006870-f5w6fw6q 5770 4 increasing increase VBG cord-006870-f5w6fw6q 5770 5 availability availability NN cord-006870-f5w6fw6q 5770 6 of of IN cord-006870-f5w6fw6q 5770 7 centers center NNS cord-006870-f5w6fw6q 5770 8 capable capable JJ cord-006870-f5w6fw6q 5770 9 of of IN cord-006870-f5w6fw6q 5770 10 delivering deliver VBG cord-006870-f5w6fw6q 5770 11 this this DT cord-006870-f5w6fw6q 5770 12 type type NN cord-006870-f5w6fw6q 5770 13 of of IN cord-006870-f5w6fw6q 5770 14 treatment treatment NN cord-006870-f5w6fw6q 5770 15 , , , cord-006870-f5w6fw6q 5770 16 suggests suggest VBZ cord-006870-f5w6fw6q 5770 17 that that IN cord-006870-f5w6fw6q 5770 18 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 5770 19 should should MD cord-006870-f5w6fw6q 5770 20 be be VB cord-006870-f5w6fw6q 5770 21 strongly strongly RB cord-006870-f5w6fw6q 5770 22 considered consider VBN cord-006870-f5w6fw6q 5770 23 in in IN cord-006870-f5w6fw6q 5770 24 VAD VAD NNP cord-006870-f5w6fw6q 5770 25 patients patient NNS cord-006870-f5w6fw6q 5770 26 with with IN cord-006870-f5w6fw6q 5770 27 acute acute JJ cord-006870-f5w6fw6q 5770 28 cerebral cerebral JJ cord-006870-f5w6fw6q 5770 29 embolism embolism NN cord-006870-f5w6fw6q 5770 30 . . . cord-006870-f5w6fw6q 5771 1 Extreme extreme JJ cord-006870-f5w6fw6q 5771 2 cerebral cerebral JJ cord-006870-f5w6fw6q 5771 3 oxygen oxygen NN cord-006870-f5w6fw6q 5771 4 changes change NNS cord-006870-f5w6fw6q 5771 5 has have VBZ cord-006870-f5w6fw6q 5771 6 not not RB cord-006870-f5w6fw6q 5771 7 been be VBN cord-006870-f5w6fw6q 5771 8 reported report VBN cord-006870-f5w6fw6q 5771 9 via via IN cord-006870-f5w6fw6q 5771 10 monitoring monitoring NN cord-006870-f5w6fw6q 5771 11 of of IN cord-006870-f5w6fw6q 5771 12 partial partial JJ cord-006870-f5w6fw6q 5771 13 brain brain NN cord-006870-f5w6fw6q 5771 14 tissue tissue NN cord-006870-f5w6fw6q 5771 15 oxygen oxygen NN cord-006870-f5w6fw6q 5771 16 levels level NNS cord-006870-f5w6fw6q 5771 17 . . . cord-006870-f5w6fw6q 5772 1 Here here RB cord-006870-f5w6fw6q 5772 2 we -PRON- PRP cord-006870-f5w6fw6q 5772 3 present present VBP cord-006870-f5w6fw6q 5772 4 an an DT cord-006870-f5w6fw6q 5772 5 aSAH asah JJ cord-006870-f5w6fw6q 5772 6 patient patient NN cord-006870-f5w6fw6q 5772 7 with with IN cord-006870-f5w6fw6q 5772 8 brain brain NN cord-006870-f5w6fw6q 5772 9 tissue tissue NN cord-006870-f5w6fw6q 5772 10 oxygen oxygen NN cord-006870-f5w6fw6q 5773 1 ( ( -LRB- cord-006870-f5w6fw6q 5773 2 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 5773 3 ) ) -RRB- cord-006870-f5w6fw6q 5773 4 monitoring monitoring NN cord-006870-f5w6fw6q 5773 5 , , , cord-006870-f5w6fw6q 5773 6 who who WP cord-006870-f5w6fw6q 5773 7 developed develop VBD cord-006870-f5w6fw6q 5773 8 cerebral cerebral JJ cord-006870-f5w6fw6q 5773 9 hypoxia hypoxia NN cord-006870-f5w6fw6q 5773 10 due due IN cord-006870-f5w6fw6q 5773 11 to to IN cord-006870-f5w6fw6q 5773 12 cerebral cerebral JJ cord-006870-f5w6fw6q 5773 13 vasospasm vasospasm NN cord-006870-f5w6fw6q 5773 14 , , , cord-006870-f5w6fw6q 5773 15 then then RB cord-006870-f5w6fw6q 5773 16 went go VBD cord-006870-f5w6fw6q 5773 17 on on RP cord-006870-f5w6fw6q 5773 18 to to TO cord-006870-f5w6fw6q 5773 19 develop develop VB cord-006870-f5w6fw6q 5773 20 cerebral cerebral JJ cord-006870-f5w6fw6q 5773 21 hyperoxia hyperoxia NN cord-006870-f5w6fw6q 5773 22 with with IN cord-006870-f5w6fw6q 5773 23 associated associated JJ cord-006870-f5w6fw6q 5773 24 cerebral cerebral JJ cord-006870-f5w6fw6q 5773 25 infarction infarction NN cord-006870-f5w6fw6q 5773 26 . . . cord-006870-f5w6fw6q 5774 1 Methods method NNS cord-006870-f5w6fw6q 5774 2 54 54 CD cord-006870-f5w6fw6q 5774 3 yo yo NN cord-006870-f5w6fw6q 5774 4 female female JJ cord-006870-f5w6fw6q 5774 5 with with IN cord-006870-f5w6fw6q 5774 6 HH5FG4 HH5FG4 NNP cord-006870-f5w6fw6q 5774 7 SAH SAH NNP cord-006870-f5w6fw6q 5774 8 with with IN cord-006870-f5w6fw6q 5774 9 initial initial JJ cord-006870-f5w6fw6q 5774 10 GCS GCS NNP cord-006870-f5w6fw6q 5774 11 of of IN cord-006870-f5w6fw6q 5774 12 3 3 CD cord-006870-f5w6fw6q 5774 13 T T NNP cord-006870-f5w6fw6q 5774 14 underwent undergo VBD cord-006870-f5w6fw6q 5774 15 coiling coiling NN cord-006870-f5w6fw6q 5774 16 of of IN cord-006870-f5w6fw6q 5774 17 a a DT cord-006870-f5w6fw6q 5774 18 ruptured ruptured JJ cord-006870-f5w6fw6q 5774 19 basilar basilar JJ cord-006870-f5w6fw6q 5774 20 tip tip NN cord-006870-f5w6fw6q 5774 21 aneurysm aneurysm NN cord-006870-f5w6fw6q 5774 22 . . . cord-006870-f5w6fw6q 5775 1 A a DT cord-006870-f5w6fw6q 5775 2 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 5775 3 monitor monitor NN cord-006870-f5w6fw6q 5775 4 was be VBD cord-006870-f5w6fw6q 5775 5 inserted insert VBN cord-006870-f5w6fw6q 5775 6 to to TO cord-006870-f5w6fw6q 5775 7 guide guide VB cord-006870-f5w6fw6q 5775 8 therapy therapy NN cord-006870-f5w6fw6q 5775 9 . . . cord-006870-f5w6fw6q 5776 1 This this DT cord-006870-f5w6fw6q 5776 2 patient patient NN cord-006870-f5w6fw6q 5776 3 had have VBD cord-006870-f5w6fw6q 5776 4 multiple multiple JJ cord-006870-f5w6fw6q 5776 5 episodes episode NNS cord-006870-f5w6fw6q 5776 6 of of IN cord-006870-f5w6fw6q 5776 7 low low JJ cord-006870-f5w6fw6q 5776 8 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 5776 9 ( ( -LRB- cord-006870-f5w6fw6q 5776 10 80 80 CD cord-006870-f5w6fw6q 5776 11 mmHg mmHg NNS cord-006870-f5w6fw6q 5776 12 ) ) -RRB- cord-006870-f5w6fw6q 5776 13 . . . cord-006870-f5w6fw6q 5777 1 This this DT cord-006870-f5w6fw6q 5777 2 corresponded correspond VBD cord-006870-f5w6fw6q 5777 3 to to IN cord-006870-f5w6fw6q 5777 4 infarction infarction NN cord-006870-f5w6fw6q 5777 5 on on IN cord-006870-f5w6fw6q 5777 6 follow follow NN cord-006870-f5w6fw6q 5777 7 up up RP cord-006870-f5w6fw6q 5777 8 head head NN cord-006870-f5w6fw6q 5777 9 CT CT NNP cord-006870-f5w6fw6q 5777 10 and and CC cord-006870-f5w6fw6q 5777 11 MRI MRI NNP cord-006870-f5w6fw6q 5777 12 with with IN cord-006870-f5w6fw6q 5777 13 preservation preservation NN cord-006870-f5w6fw6q 5777 14 of of IN cord-006870-f5w6fw6q 5777 15 local local JJ cord-006870-f5w6fw6q 5777 16 arterial arterial JJ cord-006870-f5w6fw6q 5777 17 vessels vessel NNS cord-006870-f5w6fw6q 5777 18 on on IN cord-006870-f5w6fw6q 5777 19 MRA MRA NNP cord-006870-f5w6fw6q 5777 20 , , , cord-006870-f5w6fw6q 5777 21 consistent consistent JJ cord-006870-f5w6fw6q 5777 22 with with IN cord-006870-f5w6fw6q 5777 23 diagnosis diagnosis NN cord-006870-f5w6fw6q 5777 24 of of IN cord-006870-f5w6fw6q 5777 25 DCI DCI NNP cord-006870-f5w6fw6q 5777 26 . . . cord-006870-f5w6fw6q 5778 1 In in IN cord-006870-f5w6fw6q 5778 2 the the DT cord-006870-f5w6fw6q 5778 3 present present JJ cord-006870-f5w6fw6q 5778 4 case case NN cord-006870-f5w6fw6q 5778 5 , , , cord-006870-f5w6fw6q 5778 6 high high JJ cord-006870-f5w6fw6q 5778 7 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 5778 8 is be VBZ cord-006870-f5w6fw6q 5778 9 more more RBR cord-006870-f5w6fw6q 5778 10 likely likely RB cord-006870-f5w6fw6q 5778 11 resulted result VBD cord-006870-f5w6fw6q 5778 12 from from IN cord-006870-f5w6fw6q 5778 13 a a DT cord-006870-f5w6fw6q 5778 14 combined combined JJ cord-006870-f5w6fw6q 5778 15 effect effect NN cord-006870-f5w6fw6q 5778 16 of of IN cord-006870-f5w6fw6q 5778 17 1 1 CD cord-006870-f5w6fw6q 5778 18 ) ) -RRB- cord-006870-f5w6fw6q 5778 19 increased increase VBD cord-006870-f5w6fw6q 5778 20 CBF CBF NNP cord-006870-f5w6fw6q 5778 21 from from IN cord-006870-f5w6fw6q 5778 22 co co NN cord-006870-f5w6fw6q 5778 23 - - NN cord-006870-f5w6fw6q 5778 24 administration administration NN cord-006870-f5w6fw6q 5778 25 of of IN cord-006870-f5w6fw6q 5778 26 ketamine ketamine NNP cord-006870-f5w6fw6q 5778 27 at at IN cord-006870-f5w6fw6q 5778 28 the the DT cord-006870-f5w6fw6q 5778 29 time time NN cord-006870-f5w6fw6q 5778 30 of of IN cord-006870-f5w6fw6q 5778 31 milrinone milrinone NNP cord-006870-f5w6fw6q 5778 32 infusion infusion NN cord-006870-f5w6fw6q 5778 33 ; ; : cord-006870-f5w6fw6q 5778 34 2 2 LS cord-006870-f5w6fw6q 5778 35 ) ) -RRB- cord-006870-f5w6fw6q 5778 36 decreased decrease VBD cord-006870-f5w6fw6q 5778 37 cerebral cerebral JJ cord-006870-f5w6fw6q 5778 38 metabolic metabolic JJ cord-006870-f5w6fw6q 5778 39 demands demand NNS cord-006870-f5w6fw6q 5778 40 in in IN cord-006870-f5w6fw6q 5778 41 already already RB cord-006870-f5w6fw6q 5778 42 infarcted infarcte VBN cord-006870-f5w6fw6q 5778 43 left left JJ cord-006870-f5w6fw6q 5778 44 frontal frontal JJ cord-006870-f5w6fw6q 5778 45 lobe lobe NN cord-006870-f5w6fw6q 5778 46 , , , cord-006870-f5w6fw6q 5778 47 resulting result VBG cord-006870-f5w6fw6q 5778 48 in in IN cord-006870-f5w6fw6q 5778 49 reduced reduce VBN cord-006870-f5w6fw6q 5778 50 oxygen oxygen NN cord-006870-f5w6fw6q 5778 51 uptake uptake NN cord-006870-f5w6fw6q 5778 52 ; ; : cord-006870-f5w6fw6q 5778 53 3 3 LS cord-006870-f5w6fw6q 5778 54 ) ) -RRB- cord-006870-f5w6fw6q 5778 55 accelerated accelerate VBN cord-006870-f5w6fw6q 5778 56 reperfusion reperfusion NN cord-006870-f5w6fw6q 5778 57 and and CC cord-006870-f5w6fw6q 5778 58 thus thus RB cord-006870-f5w6fw6q 5778 59 hyperemia hyperemia NNP cord-006870-f5w6fw6q 5778 60 with with IN cord-006870-f5w6fw6q 5778 61 milrinone milrinone NNP cord-006870-f5w6fw6q 5778 62 . . . cord-006870-f5w6fw6q 5779 1 Restoration restoration NN cord-006870-f5w6fw6q 5779 2 of of IN cord-006870-f5w6fw6q 5779 3 flow flow NN cord-006870-f5w6fw6q 5779 4 with with IN cord-006870-f5w6fw6q 5779 5 milrinone milrinone NNP cord-006870-f5w6fw6q 5779 6 may may MD cord-006870-f5w6fw6q 5779 7 have have VB cord-006870-f5w6fw6q 5779 8 been be VBN cord-006870-f5w6fw6q 5779 9 too too RB cord-006870-f5w6fw6q 5779 10 late late JJ cord-006870-f5w6fw6q 5779 11 to to TO cord-006870-f5w6fw6q 5779 12 reverse reverse VB cord-006870-f5w6fw6q 5779 13 the the DT cord-006870-f5w6fw6q 5779 14 prolonged prolonged JJ cord-006870-f5w6fw6q 5779 15 period period NN cord-006870-f5w6fw6q 5779 16 of of IN cord-006870-f5w6fw6q 5779 17 vasospasm vasospasm NN cord-006870-f5w6fw6q 5779 18 induced induce VBN cord-006870-f5w6fw6q 5779 19 ischemia ischemia NN cord-006870-f5w6fw6q 5779 20 , , , cord-006870-f5w6fw6q 5779 21 resulting result VBG cord-006870-f5w6fw6q 5779 22 in in IN cord-006870-f5w6fw6q 5779 23 perfusion perfusion NN cord-006870-f5w6fw6q 5779 24 of of IN cord-006870-f5w6fw6q 5779 25 infarcted infarcted JJ cord-006870-f5w6fw6q 5779 26 tissue tissue NN cord-006870-f5w6fw6q 5779 27 , , , cord-006870-f5w6fw6q 5779 28 or or CC cord-006870-f5w6fw6q 5779 29 luxury luxury NN cord-006870-f5w6fw6q 5779 30 perfusion perfusion NN cord-006870-f5w6fw6q 5779 31 . . . cord-006870-f5w6fw6q 5780 1 Clinicians clinician NNS cord-006870-f5w6fw6q 5780 2 utilizing utilize VBG cord-006870-f5w6fw6q 5780 3 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 5780 4 monitoring monitoring NN cord-006870-f5w6fw6q 5780 5 for for IN cord-006870-f5w6fw6q 5780 6 DCI DCI NNP cord-006870-f5w6fw6q 5780 7 management management NN cord-006870-f5w6fw6q 5780 8 should should MD cord-006870-f5w6fw6q 5780 9 be be VB cord-006870-f5w6fw6q 5780 10 cautious cautious JJ cord-006870-f5w6fw6q 5780 11 of of IN cord-006870-f5w6fw6q 5780 12 high high JJ cord-006870-f5w6fw6q 5780 13 PbtO2 PbtO2 NNP cord-006870-f5w6fw6q 5780 14 values value NNS cord-006870-f5w6fw6q 5780 15 , , , cord-006870-f5w6fw6q 5780 16 as as IN cord-006870-f5w6fw6q 5780 17 it -PRON- PRP cord-006870-f5w6fw6q 5780 18 may may MD cord-006870-f5w6fw6q 5780 19 herald herald VB cord-006870-f5w6fw6q 5780 20 cerebral cerebral JJ cord-006870-f5w6fw6q 5780 21 infarction infarction NN cord-006870-f5w6fw6q 5780 22 . . . cord-006870-f5w6fw6q 5781 1 Further further JJ cord-006870-f5w6fw6q 5781 2 studies study NNS cord-006870-f5w6fw6q 5781 3 are be VBP cord-006870-f5w6fw6q 5781 4 needed need VBN cord-006870-f5w6fw6q 5781 5 to to TO cord-006870-f5w6fw6q 5781 6 better better RB cord-006870-f5w6fw6q 5781 7 elucidate elucidate VB cord-006870-f5w6fw6q 5781 8 the the DT cord-006870-f5w6fw6q 5781 9 mechanism mechanism NN cord-006870-f5w6fw6q 5781 10 of of IN cord-006870-f5w6fw6q 5781 11 reperfusion reperfusion NN cord-006870-f5w6fw6q 5781 12 injury injury NN cord-006870-f5w6fw6q 5781 13 and and CC cord-006870-f5w6fw6q 5781 14 potential potential JJ cord-006870-f5w6fw6q 5781 15 treatments treatment NNS cord-006870-f5w6fw6q 5781 16 . . . cord-006870-f5w6fw6q 5782 1 Patients patient NNS cord-006870-f5w6fw6q 5782 2 with with IN cord-006870-f5w6fw6q 5782 3 acute acute JJ cord-006870-f5w6fw6q 5782 4 brain brain NN cord-006870-f5w6fw6q 5782 5 injury injury NN cord-006870-f5w6fw6q 5782 6 , , , cord-006870-f5w6fw6q 5782 7 especially especially RB cord-006870-f5w6fw6q 5782 8 those those DT cord-006870-f5w6fw6q 5782 9 with with IN cord-006870-f5w6fw6q 5782 10 intracranial intracranial JJ cord-006870-f5w6fw6q 5782 11 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 5782 12 are be VBP cord-006870-f5w6fw6q 5782 13 at at IN cord-006870-f5w6fw6q 5782 14 a a DT cord-006870-f5w6fw6q 5782 15 higher high JJR cord-006870-f5w6fw6q 5782 16 risk risk NN cord-006870-f5w6fw6q 5782 17 for for IN cord-006870-f5w6fw6q 5782 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5782 19 while while IN cord-006870-f5w6fw6q 5782 20 on on IN cord-006870-f5w6fw6q 5782 21 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5782 22 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5782 23 . . . cord-006870-f5w6fw6q 5783 1 Unfractionated unfractionated JJ cord-006870-f5w6fw6q 5783 2 heparin heparin NN cord-006870-f5w6fw6q 5783 3 ( ( -LRB- cord-006870-f5w6fw6q 5783 4 UFH UFH NNP cord-006870-f5w6fw6q 5783 5 ) ) -RRB- cord-006870-f5w6fw6q 5783 6 is be VBZ cord-006870-f5w6fw6q 5783 7 frequently frequently RB cord-006870-f5w6fw6q 5783 8 used use VBN cord-006870-f5w6fw6q 5783 9 as as IN cord-006870-f5w6fw6q 5783 10 it -PRON- PRP cord-006870-f5w6fw6q 5783 11 is be VBZ cord-006870-f5w6fw6q 5783 12 easily easily RB cord-006870-f5w6fw6q 5783 13 reversible reversible JJ cord-006870-f5w6fw6q 5783 14 and and CC cord-006870-f5w6fw6q 5783 15 has have VBZ cord-006870-f5w6fw6q 5783 16 a a DT cord-006870-f5w6fw6q 5783 17 short short JJ cord-006870-f5w6fw6q 5783 18 half half JJ cord-006870-f5w6fw6q 5783 19 - - HYPH cord-006870-f5w6fw6q 5783 20 life life NN cord-006870-f5w6fw6q 5783 21 . . . cord-006870-f5w6fw6q 5784 1 Activated activate VBN cord-006870-f5w6fw6q 5784 2 partial partial JJ cord-006870-f5w6fw6q 5784 3 thromboplastin thromboplastin NNP cord-006870-f5w6fw6q 5784 4 time time NN cord-006870-f5w6fw6q 5784 5 ( ( -LRB- cord-006870-f5w6fw6q 5784 6 aPTT aptt NN cord-006870-f5w6fw6q 5784 7 ) ) -RRB- cord-006870-f5w6fw6q 5784 8 is be VBZ cord-006870-f5w6fw6q 5784 9 traditionally traditionally RB cord-006870-f5w6fw6q 5784 10 used use VBN cord-006870-f5w6fw6q 5784 11 to to TO cord-006870-f5w6fw6q 5784 12 monitor monitor VB cord-006870-f5w6fw6q 5784 13 its -PRON- PRP$ cord-006870-f5w6fw6q 5784 14 effect effect NN cord-006870-f5w6fw6q 5784 15 . . . cord-006870-f5w6fw6q 5785 1 Several several JJ cord-006870-f5w6fw6q 5785 2 disadvantages disadvantage NNS cord-006870-f5w6fw6q 5785 3 with with IN cord-006870-f5w6fw6q 5785 4 aPTT aPTT NNS cord-006870-f5w6fw6q 5785 5 monitoring monitoring NN cord-006870-f5w6fw6q 5785 6 include include VBP cord-006870-f5w6fw6q 5785 7 inability inability NN cord-006870-f5w6fw6q 5785 8 to to TO cord-006870-f5w6fw6q 5785 9 reach reach VB cord-006870-f5w6fw6q 5785 10 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5785 11 goal goal NN cord-006870-f5w6fw6q 5785 12 , , , cord-006870-f5w6fw6q 5785 13 over over IN cord-006870-f5w6fw6q 5785 14 - - HYPH cord-006870-f5w6fw6q 5785 15 or or CC cord-006870-f5w6fw6q 5785 16 under under NN cord-006870-f5w6fw6q 5785 17 - - HYPH cord-006870-f5w6fw6q 5785 18 dosing dosing NN cord-006870-f5w6fw6q 5785 19 and and CC cord-006870-f5w6fw6q 5785 20 its -PRON- PRP$ cord-006870-f5w6fw6q 5785 21 associated associated JJ cord-006870-f5w6fw6q 5785 22 complications complication NNS cord-006870-f5w6fw6q 5785 23 . . . cord-006870-f5w6fw6q 5786 1 Anti Anti NNP cord-006870-f5w6fw6q 5786 2 - - JJ cord-006870-f5w6fw6q 5786 3 Xa xa JJ cord-006870-f5w6fw6q 5786 4 level level NN cord-006870-f5w6fw6q 5786 5 is be VBZ cord-006870-f5w6fw6q 5786 6 reported report VBN cord-006870-f5w6fw6q 5786 7 to to TO cord-006870-f5w6fw6q 5786 8 have have VB cord-006870-f5w6fw6q 5786 9 better well JJR cord-006870-f5w6fw6q 5786 10 correlation correlation NN cord-006870-f5w6fw6q 5786 11 with with IN cord-006870-f5w6fw6q 5786 12 actual actual JJ cord-006870-f5w6fw6q 5786 13 degree degree NN cord-006870-f5w6fw6q 5786 14 of of IN cord-006870-f5w6fw6q 5786 15 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5786 16 using use VBG cord-006870-f5w6fw6q 5786 17 UFH UFH NNP cord-006870-f5w6fw6q 5786 18 . . . cord-006870-f5w6fw6q 5787 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 5787 2 chart chart NN cord-006870-f5w6fw6q 5787 3 review review NN cord-006870-f5w6fw6q 5787 4 of of IN cord-006870-f5w6fw6q 5787 5 3 3 CD cord-006870-f5w6fw6q 5787 6 patients patient NNS cord-006870-f5w6fw6q 5787 7 with with IN cord-006870-f5w6fw6q 5787 8 acute acute JJ cord-006870-f5w6fw6q 5787 9 brain brain NN cord-006870-f5w6fw6q 5787 10 injury injury NN cord-006870-f5w6fw6q 5787 11 who who WP cord-006870-f5w6fw6q 5787 12 required require VBD cord-006870-f5w6fw6q 5787 13 initiation initiation NN cord-006870-f5w6fw6q 5787 14 of of IN cord-006870-f5w6fw6q 5787 15 early early JJ cord-006870-f5w6fw6q 5787 16 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5787 17 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5787 18 and and CC cord-006870-f5w6fw6q 5787 19 monitored monitor VBN cord-006870-f5w6fw6q 5787 20 with with IN cord-006870-f5w6fw6q 5787 21 anti anti JJ cord-006870-f5w6fw6q 5787 22 - - JJ cord-006870-f5w6fw6q 5787 23 Xa xa JJ cord-006870-f5w6fw6q 5787 24 level level NN cord-006870-f5w6fw6q 5787 25 . . . cord-006870-f5w6fw6q 5788 1 Case case NN cord-006870-f5w6fw6q 5788 2 1 1 CD cord-006870-f5w6fw6q 5789 1 -30 -30 : cord-006870-f5w6fw6q 5789 2 year year NN cord-006870-f5w6fw6q 5789 3 - - HYPH cord-006870-f5w6fw6q 5789 4 old old JJ cord-006870-f5w6fw6q 5789 5 - - HYPH cord-006870-f5w6fw6q 5789 6 man man NN cord-006870-f5w6fw6q 5789 7 with with IN cord-006870-f5w6fw6q 5789 8 intracerebral intracerebral JJ cord-006870-f5w6fw6q 5789 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5789 10 ( ( -LRB- cord-006870-f5w6fw6q 5789 11 ICH ICH NNP cord-006870-f5w6fw6q 5789 12 ) ) -RRB- cord-006870-f5w6fw6q 5789 13 developed develop VBD cord-006870-f5w6fw6q 5789 14 lower low JJR cord-006870-f5w6fw6q 5789 15 extremity extremity NN cord-006870-f5w6fw6q 5789 16 deep deep JJ cord-006870-f5w6fw6q 5789 17 vein vein NN cord-006870-f5w6fw6q 5789 18 thrombosis thrombosis NN cord-006870-f5w6fw6q 5789 19 ( ( -LRB- cord-006870-f5w6fw6q 5789 20 DVT DVT NNP cord-006870-f5w6fw6q 5789 21 ) ) -RRB- cord-006870-f5w6fw6q 5789 22 and and CC cord-006870-f5w6fw6q 5789 23 required require VBN cord-006870-f5w6fw6q 5789 24 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5789 25 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5789 26 . . . cord-006870-f5w6fw6q 5790 1 Patient Patient NNP cord-006870-f5w6fw6q 5790 2 became become VBD cord-006870-f5w6fw6q 5790 3 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5790 4 within within IN cord-006870-f5w6fw6q 5790 5 six six CD cord-006870-f5w6fw6q 5790 6 hours hour NNS cord-006870-f5w6fw6q 5790 7 of of IN cord-006870-f5w6fw6q 5790 8 titrating titrate VBG cord-006870-f5w6fw6q 5790 9 infusion infusion NN cord-006870-f5w6fw6q 5790 10 based base VBN cord-006870-f5w6fw6q 5790 11 of of IN cord-006870-f5w6fw6q 5790 12 anti anti JJ cord-006870-f5w6fw6q 5790 13 - - JJ cord-006870-f5w6fw6q 5790 14 Xa xa JJ cord-006870-f5w6fw6q 5790 15 levels level NNS cord-006870-f5w6fw6q 5790 16 and and CC cord-006870-f5w6fw6q 5790 17 remained remain VBD cord-006870-f5w6fw6q 5790 18 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5790 19 . . . cord-006870-f5w6fw6q 5791 1 Asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 5791 2 rectal rectal JJ cord-006870-f5w6fw6q 5791 3 bleeding bleeding NN cord-006870-f5w6fw6q 5791 4 associated associate VBN cord-006870-f5w6fw6q 5791 5 with with IN cord-006870-f5w6fw6q 5791 6 fecal fecal JJ cord-006870-f5w6fw6q 5791 7 management management NN cord-006870-f5w6fw6q 5791 8 system system NN cord-006870-f5w6fw6q 5791 9 was be VBD cord-006870-f5w6fw6q 5791 10 noted note VBN cord-006870-f5w6fw6q 5791 11 . . . cord-006870-f5w6fw6q 5792 1 Case case NN cord-006870-f5w6fw6q 5792 2 2 2 CD cord-006870-f5w6fw6q 5793 1 -26 -26 CD cord-006870-f5w6fw6q 5793 2 year year NN cord-006870-f5w6fw6q 5793 3 - - HYPH cord-006870-f5w6fw6q 5793 4 old old JJ cord-006870-f5w6fw6q 5793 5 - - HYPH cord-006870-f5w6fw6q 5793 6 man man NN cord-006870-f5w6fw6q 5793 7 with with IN cord-006870-f5w6fw6q 5793 8 cerebral cerebral JJ cord-006870-f5w6fw6q 5793 9 venous venous JJ cord-006870-f5w6fw6q 5793 10 sinus sinus NN cord-006870-f5w6fw6q 5793 11 thrombosis thrombosis NN cord-006870-f5w6fw6q 5793 12 presented present VBD cord-006870-f5w6fw6q 5793 13 required require VBN cord-006870-f5w6fw6q 5793 14 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5793 15 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5793 16 . . . cord-006870-f5w6fw6q 5794 1 UFH UFH NNP cord-006870-f5w6fw6q 5794 2 infusion infusion NN cord-006870-f5w6fw6q 5794 3 was be VBD cord-006870-f5w6fw6q 5794 4 initially initially RB cord-006870-f5w6fw6q 5794 5 monitored monitor VBN cord-006870-f5w6fw6q 5794 6 using use VBG cord-006870-f5w6fw6q 5794 7 aPTT aptt CD cord-006870-f5w6fw6q 5794 8 levels level NNS cord-006870-f5w6fw6q 5794 9 which which WDT cord-006870-f5w6fw6q 5794 10 had have VBD cord-006870-f5w6fw6q 5794 11 widely widely RB cord-006870-f5w6fw6q 5794 12 varied varied JJ cord-006870-f5w6fw6q 5794 13 lab lab NN cord-006870-f5w6fw6q 5794 14 results result NNS cord-006870-f5w6fw6q 5794 15 , , , cord-006870-f5w6fw6q 5794 16 thus thus RB cord-006870-f5w6fw6q 5794 17 monitoring monitoring NN cord-006870-f5w6fw6q 5794 18 was be VBD cord-006870-f5w6fw6q 5794 19 switched switch VBN cord-006870-f5w6fw6q 5794 20 to to IN cord-006870-f5w6fw6q 5794 21 anti anti JJ cord-006870-f5w6fw6q 5794 22 - - JJ cord-006870-f5w6fw6q 5794 23 Xa xa JJ cord-006870-f5w6fw6q 5794 24 levels level NNS cord-006870-f5w6fw6q 5794 25 which which WDT cord-006870-f5w6fw6q 5794 26 provided provide VBD cord-006870-f5w6fw6q 5794 27 a a DT cord-006870-f5w6fw6q 5794 28 more more RBR cord-006870-f5w6fw6q 5794 29 consistent consistent JJ cord-006870-f5w6fw6q 5794 30 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5794 31 range range NN cord-006870-f5w6fw6q 5794 32 . . . cord-006870-f5w6fw6q 5795 1 However however RB cord-006870-f5w6fw6q 5795 2 , , , cord-006870-f5w6fw6q 5795 3 patient patient JJ cord-006870-f5w6fw6q 5795 4 developed develop VBN cord-006870-f5w6fw6q 5795 5 thrombocytopenia thrombocytopenia NN cord-006870-f5w6fw6q 5795 6 in in IN cord-006870-f5w6fw6q 5795 7 the the DT cord-006870-f5w6fw6q 5795 8 setting setting NN cord-006870-f5w6fw6q 5795 9 of of IN cord-006870-f5w6fw6q 5795 10 inflammatory inflammatory JJ cord-006870-f5w6fw6q 5795 11 bowel bowel NN cord-006870-f5w6fw6q 5795 12 disease disease NN cord-006870-f5w6fw6q 5795 13 . . . cord-006870-f5w6fw6q 5796 1 Therefore therefore RB cord-006870-f5w6fw6q 5796 2 , , , cord-006870-f5w6fw6q 5796 3 UFH UFH NNP cord-006870-f5w6fw6q 5796 4 infusion infusion NN cord-006870-f5w6fw6q 5796 5 was be VBD cord-006870-f5w6fw6q 5796 6 changed change VBN cord-006870-f5w6fw6q 5796 7 to to IN cord-006870-f5w6fw6q 5796 8 Argatroban Argatroban NNP cord-006870-f5w6fw6q 5796 9 infusion infusion NN cord-006870-f5w6fw6q 5796 10 . . . cord-006870-f5w6fw6q 5797 1 Case case NN cord-006870-f5w6fw6q 5797 2 3 3 CD cord-006870-f5w6fw6q 5797 3 -22 -22 IN cord-006870-f5w6fw6q 5797 4 year year NN cord-006870-f5w6fw6q 5797 5 - - HYPH cord-006870-f5w6fw6q 5797 6 old old JJ cord-006870-f5w6fw6q 5797 7 - - HYPH cord-006870-f5w6fw6q 5797 8 man man NN cord-006870-f5w6fw6q 5797 9 with with IN cord-006870-f5w6fw6q 5797 10 lower low JJR cord-006870-f5w6fw6q 5797 11 medullary medullary JJ cord-006870-f5w6fw6q 5797 12 acute acute JJ cord-006870-f5w6fw6q 5797 13 ischemic ischemic JJ cord-006870-f5w6fw6q 5797 14 stroke stroke NN cord-006870-f5w6fw6q 5797 15 due due JJ cord-006870-f5w6fw6q 5797 16 vertebral vertebral JJ cord-006870-f5w6fw6q 5797 17 artery artery NN cord-006870-f5w6fw6q 5797 18 dissection dissection NN cord-006870-f5w6fw6q 5797 19 required require VBD cord-006870-f5w6fw6q 5797 20 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5797 21 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5797 22 to to TO cord-006870-f5w6fw6q 5797 23 prevent prevent VB cord-006870-f5w6fw6q 5797 24 recurrence recurrence NN cord-006870-f5w6fw6q 5797 25 . . . cord-006870-f5w6fw6q 5798 1 Patient Patient NNP cord-006870-f5w6fw6q 5798 2 became become VBD cord-006870-f5w6fw6q 5798 3 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5798 4 within within IN cord-006870-f5w6fw6q 5798 5 27 27 CD cord-006870-f5w6fw6q 5798 6 hours hour NNS cord-006870-f5w6fw6q 5798 7 of of IN cord-006870-f5w6fw6q 5798 8 titrating titrate VBG cord-006870-f5w6fw6q 5798 9 based base VBN cord-006870-f5w6fw6q 5798 10 of of IN cord-006870-f5w6fw6q 5798 11 anti anti JJ cord-006870-f5w6fw6q 5798 12 - - JJ cord-006870-f5w6fw6q 5798 13 Xa xa JJ cord-006870-f5w6fw6q 5798 14 levels level NNS cord-006870-f5w6fw6q 5798 15 . . . cord-006870-f5w6fw6q 5799 1 To to TO cord-006870-f5w6fw6q 5799 2 monitor monitor VB cord-006870-f5w6fw6q 5799 3 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5799 4 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5799 5 , , , cord-006870-f5w6fw6q 5799 6 anti anti JJ cord-006870-f5w6fw6q 5799 7 - - JJ cord-006870-f5w6fw6q 5799 8 Xa xa JJ cord-006870-f5w6fw6q 5799 9 level level NN cord-006870-f5w6fw6q 5799 10 appears appear VBZ cord-006870-f5w6fw6q 5799 11 to to TO cord-006870-f5w6fw6q 5799 12 achieve achieve VB cord-006870-f5w6fw6q 5799 13 target target NN cord-006870-f5w6fw6q 5799 14 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5799 15 level level NN cord-006870-f5w6fw6q 5799 16 faster fast RBR cord-006870-f5w6fw6q 5799 17 and and CC cord-006870-f5w6fw6q 5799 18 without without IN cord-006870-f5w6fw6q 5799 19 serial serial JJ cord-006870-f5w6fw6q 5799 20 variation variation NN cord-006870-f5w6fw6q 5799 21 as as IN cord-006870-f5w6fw6q 5799 22 compared compare VBN cord-006870-f5w6fw6q 5799 23 to to IN cord-006870-f5w6fw6q 5799 24 aPTT aptt NN cord-006870-f5w6fw6q 5799 25 . . . cord-006870-f5w6fw6q 5800 1 However however RB cord-006870-f5w6fw6q 5800 2 , , , cord-006870-f5w6fw6q 5800 3 anti anti JJ cord-006870-f5w6fw6q 5800 4 - - JJ cord-006870-f5w6fw6q 5800 5 Xa xa JJ cord-006870-f5w6fw6q 5800 6 level level NN cord-006870-f5w6fw6q 5800 7 estimation estimation NN cord-006870-f5w6fw6q 5800 8 is be VBZ cord-006870-f5w6fw6q 5800 9 costlier costly JJR cord-006870-f5w6fw6q 5800 10 as as IN cord-006870-f5w6fw6q 5800 11 compared compare VBN cord-006870-f5w6fw6q 5800 12 to to IN cord-006870-f5w6fw6q 5800 13 aPTT aptt NN cord-006870-f5w6fw6q 5800 14 and and CC cord-006870-f5w6fw6q 5800 15 not not RB cord-006870-f5w6fw6q 5800 16 widely widely RB cord-006870-f5w6fw6q 5800 17 available available JJ cord-006870-f5w6fw6q 5800 18 . . . cord-006870-f5w6fw6q 5801 1 By by IN cord-006870-f5w6fw6q 5801 2 restricting restrict VBG cord-006870-f5w6fw6q 5801 3 it -PRON- PRP cord-006870-f5w6fw6q 5801 4 to to IN cord-006870-f5w6fw6q 5801 5 special special JJ cord-006870-f5w6fw6q 5801 6 populations population NNS cord-006870-f5w6fw6q 5801 7 like like IN cord-006870-f5w6fw6q 5801 8 those those DT cord-006870-f5w6fw6q 5801 9 with with IN cord-006870-f5w6fw6q 5801 10 acute acute JJ cord-006870-f5w6fw6q 5801 11 brain brain NN cord-006870-f5w6fw6q 5801 12 injury injury NN cord-006870-f5w6fw6q 5801 13 might may MD cord-006870-f5w6fw6q 5801 14 justify justify VB cord-006870-f5w6fw6q 5801 15 its -PRON- PRP$ cord-006870-f5w6fw6q 5801 16 use use NN cord-006870-f5w6fw6q 5801 17 and and CC cord-006870-f5w6fw6q 5801 18 underscore underscore VB cord-006870-f5w6fw6q 5801 19 cost cost NN cord-006870-f5w6fw6q 5801 20 - - HYPH cord-006870-f5w6fw6q 5801 21 effectiveness effectiveness NN cord-006870-f5w6fw6q 5801 22 . . . cord-006870-f5w6fw6q 5802 1 Neurological neurological JJ cord-006870-f5w6fw6q 5802 2 admissions admission NNS cord-006870-f5w6fw6q 5802 3 presenting present VBG cord-006870-f5w6fw6q 5802 4 to to IN cord-006870-f5w6fw6q 5802 5 the the DT cord-006870-f5w6fw6q 5802 6 ICU ICU NNP cord-006870-f5w6fw6q 5802 7 benefit benefit NN cord-006870-f5w6fw6q 5802 8 from from IN cord-006870-f5w6fw6q 5802 9 a a DT cord-006870-f5w6fw6q 5802 10 dedicated dedicated JJ cord-006870-f5w6fw6q 5802 11 neurocritical neurocritical NNP cord-006870-f5w6fw6q 5802 12 care care NN cord-006870-f5w6fw6q 5802 13 team team NN cord-006870-f5w6fw6q 5802 14 but but CC cord-006870-f5w6fw6q 5802 15 many many JJ cord-006870-f5w6fw6q 5802 16 community community NN cord-006870-f5w6fw6q 5802 17 hospitals hospital NNS cord-006870-f5w6fw6q 5802 18 lack lack VBP cord-006870-f5w6fw6q 5802 19 this this DT cord-006870-f5w6fw6q 5802 20 subspecialty subspecialty JJ cord-006870-f5w6fw6q 5802 21 expertise expertise NN cord-006870-f5w6fw6q 5802 22 . . . cord-006870-f5w6fw6q 5803 1 With with IN cord-006870-f5w6fw6q 5803 2 an an DT cord-006870-f5w6fw6q 5803 3 aging age VBG cord-006870-f5w6fw6q 5803 4 population population NN cord-006870-f5w6fw6q 5803 5 and and CC cord-006870-f5w6fw6q 5803 6 a a DT cord-006870-f5w6fw6q 5803 7 neurointensivist neurointensivist JJ cord-006870-f5w6fw6q 5803 8 shortage shortage NN cord-006870-f5w6fw6q 5803 9 , , , cord-006870-f5w6fw6q 5803 10 more more JJR cord-006870-f5w6fw6q 5803 11 patients patient NNS cord-006870-f5w6fw6q 5803 12 are be VBP cord-006870-f5w6fw6q 5803 13 transferred transfer VBN cord-006870-f5w6fw6q 5803 14 to to IN cord-006870-f5w6fw6q 5803 15 designated designate VBN cord-006870-f5w6fw6q 5803 16 neurocritical neurocritical JJ cord-006870-f5w6fw6q 5803 17 care care NN cord-006870-f5w6fw6q 5803 18 units unit NNS cord-006870-f5w6fw6q 5803 19 which which WDT cord-006870-f5w6fw6q 5803 20 increases increase VBZ cord-006870-f5w6fw6q 5803 21 healthcare healthcare NN cord-006870-f5w6fw6q 5803 22 spending spending NN cord-006870-f5w6fw6q 5803 23 and and CC cord-006870-f5w6fw6q 5803 24 resource resource NN cord-006870-f5w6fw6q 5803 25 utilization utilization NN cord-006870-f5w6fw6q 5803 26 . . . cord-006870-f5w6fw6q 5804 1 Recognizing recognize VBG cord-006870-f5w6fw6q 5804 2 this this DT cord-006870-f5w6fw6q 5804 3 obstacle obstacle NN cord-006870-f5w6fw6q 5804 4 , , , cord-006870-f5w6fw6q 5804 5 we -PRON- PRP cord-006870-f5w6fw6q 5804 6 describe describe VBP cord-006870-f5w6fw6q 5804 7 the the DT cord-006870-f5w6fw6q 5804 8 management management NN cord-006870-f5w6fw6q 5804 9 of of IN cord-006870-f5w6fw6q 5804 10 a a DT cord-006870-f5w6fw6q 5804 11 patient patient NN cord-006870-f5w6fw6q 5804 12 in in IN cord-006870-f5w6fw6q 5804 13 status status NN cord-006870-f5w6fw6q 5804 14 epilepticus epilepticus NN cord-006870-f5w6fw6q 5804 15 via via IN cord-006870-f5w6fw6q 5804 16 our -PRON- PRP$ cord-006870-f5w6fw6q 5804 17 novel novel NN cord-006870-f5w6fw6q 5804 18 " " `` cord-006870-f5w6fw6q 5804 19 eNeuro eNeuro NNP cord-006870-f5w6fw6q 5804 20 - - HYPH cord-006870-f5w6fw6q 5804 21 ICU ICU NNP cord-006870-f5w6fw6q 5804 22 " " '' cord-006870-f5w6fw6q 5804 23 consult consult VBP cord-006870-f5w6fw6q 5804 24 program program NN cord-006870-f5w6fw6q 5804 25 in in IN cord-006870-f5w6fw6q 5804 26 which which WDT cord-006870-f5w6fw6q 5804 27 a a DT cord-006870-f5w6fw6q 5804 28 ' ' `` cord-006870-f5w6fw6q 5804 29 sub sub JJ cord-006870-f5w6fw6q 5804 30 - - JJ cord-006870-f5w6fw6q 5804 31 hub hub NN cord-006870-f5w6fw6q 5804 32 ' ' '' cord-006870-f5w6fw6q 5804 33 of of IN cord-006870-f5w6fw6q 5804 34 the the DT cord-006870-f5w6fw6q 5804 35 Northwell Northwell NNP cord-006870-f5w6fw6q 5804 36 Health Health NNP cord-006870-f5w6fw6q 5804 37 Tele Tele NNP cord-006870-f5w6fw6q 5804 38 - - HYPH cord-006870-f5w6fw6q 5804 39 ICU ICU NNP cord-006870-f5w6fw6q 5804 40 was be VBD cord-006870-f5w6fw6q 5804 41 set set VBN cord-006870-f5w6fw6q 5804 42 up up RP cord-006870-f5w6fw6q 5804 43 at at IN cord-006870-f5w6fw6q 5804 44 the the DT cord-006870-f5w6fw6q 5804 45 only only JJ cord-006870-f5w6fw6q 5804 46 hospital hospital NN cord-006870-f5w6fw6q 5804 47 out out IN cord-006870-f5w6fw6q 5804 48 of of IN cord-006870-f5w6fw6q 5804 49 19 19 CD cord-006870-f5w6fw6q 5804 50 in in IN cord-006870-f5w6fw6q 5804 51 our -PRON- PRP$ cord-006870-f5w6fw6q 5804 52 health health NN cord-006870-f5w6fw6q 5804 53 system system NN cord-006870-f5w6fw6q 5804 54 that that WDT cord-006870-f5w6fw6q 5804 55 is be VBZ cord-006870-f5w6fw6q 5804 56 staffed staff VBN cord-006870-f5w6fw6q 5804 57 24/7 24/7 RB cord-006870-f5w6fw6q 5804 58 by by IN cord-006870-f5w6fw6q 5804 59 neurointensivists neurointensivist NNS cord-006870-f5w6fw6q 5804 60 . . . cord-006870-f5w6fw6q 5805 1 A a DT cord-006870-f5w6fw6q 5805 2 56-year 56-year JJ cord-006870-f5w6fw6q 5805 3 - - HYPH cord-006870-f5w6fw6q 5805 4 old old JJ cord-006870-f5w6fw6q 5805 5 man man NN cord-006870-f5w6fw6q 5805 6 with with IN cord-006870-f5w6fw6q 5805 7 history history NN cord-006870-f5w6fw6q 5805 8 of of IN cord-006870-f5w6fw6q 5805 9 a a DT cord-006870-f5w6fw6q 5805 10 left left JJ cord-006870-f5w6fw6q 5805 11 frontal frontal JJ cord-006870-f5w6fw6q 5805 12 meningioma meningioma NN cord-006870-f5w6fw6q 5805 13 presented present VBN cord-006870-f5w6fw6q 5805 14 with with IN cord-006870-f5w6fw6q 5805 15 multiple multiple JJ cord-006870-f5w6fw6q 5805 16 seizures seizure NNS cord-006870-f5w6fw6q 5805 17 to to IN cord-006870-f5w6fw6q 5805 18 a a DT cord-006870-f5w6fw6q 5805 19 hospital hospital NN cord-006870-f5w6fw6q 5805 20 within within IN cord-006870-f5w6fw6q 5805 21 our -PRON- PRP$ cord-006870-f5w6fw6q 5805 22 healthcare healthcare NN cord-006870-f5w6fw6q 5805 23 system system NN cord-006870-f5w6fw6q 5805 24 . . . cord-006870-f5w6fw6q 5806 1 He -PRON- PRP cord-006870-f5w6fw6q 5806 2 received receive VBD cord-006870-f5w6fw6q 5806 3 6 6 CD cord-006870-f5w6fw6q 5806 4 mg mg NN cord-006870-f5w6fw6q 5806 5 of of IN cord-006870-f5w6fw6q 5806 6 lorazepam lorazepam NNP cord-006870-f5w6fw6q 5806 7 and and CC cord-006870-f5w6fw6q 5806 8 levetiracitam levetiracitam NNS cord-006870-f5w6fw6q 5806 9 in in IN cord-006870-f5w6fw6q 5806 10 the the DT cord-006870-f5w6fw6q 5806 11 emergency emergency NN cord-006870-f5w6fw6q 5806 12 department department NN cord-006870-f5w6fw6q 5806 13 and and CC cord-006870-f5w6fw6q 5806 14 was be VBD cord-006870-f5w6fw6q 5806 15 admitted admit VBN cord-006870-f5w6fw6q 5806 16 to to IN cord-006870-f5w6fw6q 5806 17 the the DT cord-006870-f5w6fw6q 5806 18 ICU ICU NNP cord-006870-f5w6fw6q 5806 19 for for IN cord-006870-f5w6fw6q 5806 20 further further JJ cord-006870-f5w6fw6q 5806 21 monitoring monitoring NN cord-006870-f5w6fw6q 5806 22 . . . cord-006870-f5w6fw6q 5807 1 There there RB cord-006870-f5w6fw6q 5807 2 he -PRON- PRP cord-006870-f5w6fw6q 5807 3 was be VBD cord-006870-f5w6fw6q 5807 4 witnessed witness VBN cord-006870-f5w6fw6q 5807 5 to to TO cord-006870-f5w6fw6q 5807 6 have have VB cord-006870-f5w6fw6q 5807 7 recurrence recurrence NN cord-006870-f5w6fw6q 5807 8 of of IN cord-006870-f5w6fw6q 5807 9 clinical clinical JJ cord-006870-f5w6fw6q 5807 10 activity activity NN cord-006870-f5w6fw6q 5807 11 concerning concern VBG cord-006870-f5w6fw6q 5807 12 for for IN cord-006870-f5w6fw6q 5807 13 ongoing ongoing JJ cord-006870-f5w6fw6q 5807 14 seizure seizure NN cord-006870-f5w6fw6q 5807 15 . . . cord-006870-f5w6fw6q 5808 1 Levetiracitam Levetiracitam NNP cord-006870-f5w6fw6q 5808 2 was be VBD cord-006870-f5w6fw6q 5808 3 increased increase VBN cord-006870-f5w6fw6q 5808 4 and and CC cord-006870-f5w6fw6q 5808 5 phenytoin phenytoin NN cord-006870-f5w6fw6q 5808 6 was be VBD cord-006870-f5w6fw6q 5808 7 added add VBN cord-006870-f5w6fw6q 5808 8 . . . cord-006870-f5w6fw6q 5809 1 Neither neither DT cord-006870-f5w6fw6q 5809 2 immediate immediate JJ cord-006870-f5w6fw6q 5809 3 neurological neurological JJ cord-006870-f5w6fw6q 5809 4 consult consult NN cord-006870-f5w6fw6q 5809 5 nor nor CC cord-006870-f5w6fw6q 5809 6 continuous continuous JJ cord-006870-f5w6fw6q 5809 7 EEG EEG NNP cord-006870-f5w6fw6q 5809 8 was be VBD cord-006870-f5w6fw6q 5809 9 available available JJ cord-006870-f5w6fw6q 5809 10 , , , cord-006870-f5w6fw6q 5809 11 thus thus RB cord-006870-f5w6fw6q 5809 12 an an DT cord-006870-f5w6fw6q 5809 13 " " `` cord-006870-f5w6fw6q 5809 14 eNeuro eNeuro NNP cord-006870-f5w6fw6q 5809 15 - - HYPH cord-006870-f5w6fw6q 5809 16 ICU ICU NNP cord-006870-f5w6fw6q 5809 17 " " '' cord-006870-f5w6fw6q 5809 18 consult consult NN cord-006870-f5w6fw6q 5809 19 was be VBD cord-006870-f5w6fw6q 5809 20 obtained obtain VBN cord-006870-f5w6fw6q 5809 21 . . . cord-006870-f5w6fw6q 5810 1 In in IN cord-006870-f5w6fw6q 5810 2 this this DT cord-006870-f5w6fw6q 5810 3 model model NN cord-006870-f5w6fw6q 5810 4 , , , cord-006870-f5w6fw6q 5810 5 the the DT cord-006870-f5w6fw6q 5810 6 bedside bedside NN cord-006870-f5w6fw6q 5810 7 provider provider NN cord-006870-f5w6fw6q 5810 8 contacts contact VBZ cord-006870-f5w6fw6q 5810 9 the the DT cord-006870-f5w6fw6q 5810 10 Tele Tele NNP cord-006870-f5w6fw6q 5810 11 - - HYPH cord-006870-f5w6fw6q 5810 12 ICU ICU NNP cord-006870-f5w6fw6q 5810 13 that that WDT cord-006870-f5w6fw6q 5810 14 facilitates facilitate VBZ cord-006870-f5w6fw6q 5810 15 a a DT cord-006870-f5w6fw6q 5810 16 conference conference NN cord-006870-f5w6fw6q 5810 17 call call NN cord-006870-f5w6fw6q 5810 18 with with IN cord-006870-f5w6fw6q 5810 19 the the DT cord-006870-f5w6fw6q 5810 20 neurointensivist neurointensivist NN cord-006870-f5w6fw6q 5810 21 . . . cord-006870-f5w6fw6q 5811 1 AV av NN cord-006870-f5w6fw6q 5811 2 technology technology NN cord-006870-f5w6fw6q 5811 3 was be VBD cord-006870-f5w6fw6q 5811 4 used use VBN cord-006870-f5w6fw6q 5811 5 to to TO cord-006870-f5w6fw6q 5811 6 provide provide VB cord-006870-f5w6fw6q 5811 7 consultations consultation NNS cord-006870-f5w6fw6q 5811 8 and and CC cord-006870-f5w6fw6q 5811 9 follow follow VB cord-006870-f5w6fw6q 5811 10 ups up NNS cord-006870-f5w6fw6q 5811 11 . . . cord-006870-f5w6fw6q 5812 1 The the DT cord-006870-f5w6fw6q 5812 2 neurointensivist neurointensivist NN cord-006870-f5w6fw6q 5812 3 determined determine VBD cord-006870-f5w6fw6q 5812 4 the the DT cord-006870-f5w6fw6q 5812 5 patient patient NN cord-006870-f5w6fw6q 5812 6 was be VBD cord-006870-f5w6fw6q 5812 7 rapidly rapidly RB cord-006870-f5w6fw6q 5812 8 returning return VBG cord-006870-f5w6fw6q 5812 9 to to IN cord-006870-f5w6fw6q 5812 10 baseline baseline NN cord-006870-f5w6fw6q 5812 11 and and CC cord-006870-f5w6fw6q 5812 12 recommended recommend VBD cord-006870-f5w6fw6q 5812 13 a a DT cord-006870-f5w6fw6q 5812 14 head head NN cord-006870-f5w6fw6q 5812 15 CT CT NNP cord-006870-f5w6fw6q 5812 16 , , , cord-006870-f5w6fw6q 5812 17 lab lab NN cord-006870-f5w6fw6q 5812 18 studies study NNS cord-006870-f5w6fw6q 5812 19 and and CC cord-006870-f5w6fw6q 5812 20 continuation continuation NN cord-006870-f5w6fw6q 5812 21 of of IN cord-006870-f5w6fw6q 5812 22 the the DT cord-006870-f5w6fw6q 5812 23 anti anti JJ cord-006870-f5w6fw6q 5812 24 - - JJ cord-006870-f5w6fw6q 5812 25 epileptic epileptic JJ cord-006870-f5w6fw6q 5812 26 drugs drug NNS cord-006870-f5w6fw6q 5812 27 . . . cord-006870-f5w6fw6q 5813 1 The the DT cord-006870-f5w6fw6q 5813 2 eICU eicu JJ cord-006870-f5w6fw6q 5813 3 team team NN cord-006870-f5w6fw6q 5813 4 monitored monitor VBD cord-006870-f5w6fw6q 5813 5 the the DT cord-006870-f5w6fw6q 5813 6 patient patient NN cord-006870-f5w6fw6q 5813 7 overnight overnight RB cord-006870-f5w6fw6q 5813 8 . . . cord-006870-f5w6fw6q 5814 1 By by IN cord-006870-f5w6fw6q 5814 2 leveraging leverage VBG cord-006870-f5w6fw6q 5814 3 the the DT cord-006870-f5w6fw6q 5814 4 infrastructure infrastructure NN cord-006870-f5w6fw6q 5814 5 in in IN cord-006870-f5w6fw6q 5814 6 place place NN cord-006870-f5w6fw6q 5814 7 for for IN cord-006870-f5w6fw6q 5814 8 management management NN cord-006870-f5w6fw6q 5814 9 of of IN cord-006870-f5w6fw6q 5814 10 critically critically RB cord-006870-f5w6fw6q 5814 11 ill ill JJ cord-006870-f5w6fw6q 5814 12 patients patient NNS cord-006870-f5w6fw6q 5814 13 remotely remotely RB cord-006870-f5w6fw6q 5814 14 , , , cord-006870-f5w6fw6q 5814 15 an an DT cord-006870-f5w6fw6q 5814 16 additional additional JJ cord-006870-f5w6fw6q 5814 17 level level NN cord-006870-f5w6fw6q 5814 18 of of IN cord-006870-f5w6fw6q 5814 19 subspecialty subspecialty JJ cord-006870-f5w6fw6q 5814 20 care care NN cord-006870-f5w6fw6q 5814 21 was be VBD cord-006870-f5w6fw6q 5814 22 offered offer VBN cord-006870-f5w6fw6q 5814 23 in in IN cord-006870-f5w6fw6q 5814 24 a a DT cord-006870-f5w6fw6q 5814 25 timely timely JJ cord-006870-f5w6fw6q 5814 26 manner manner NN cord-006870-f5w6fw6q 5814 27 and and CC cord-006870-f5w6fw6q 5814 28 allowed allow VBD cord-006870-f5w6fw6q 5814 29 the the DT cord-006870-f5w6fw6q 5814 30 patient patient NN cord-006870-f5w6fw6q 5814 31 to to TO cord-006870-f5w6fw6q 5814 32 remain remain VB cord-006870-f5w6fw6q 5814 33 at at IN cord-006870-f5w6fw6q 5814 34 their -PRON- PRP$ cord-006870-f5w6fw6q 5814 35 local local JJ cord-006870-f5w6fw6q 5814 36 facility facility NN cord-006870-f5w6fw6q 5814 37 . . . cord-006870-f5w6fw6q 5815 1 Based base VBN cord-006870-f5w6fw6q 5815 2 on on IN cord-006870-f5w6fw6q 5815 3 the the DT cord-006870-f5w6fw6q 5815 4 success success NN cord-006870-f5w6fw6q 5815 5 of of IN cord-006870-f5w6fw6q 5815 6 the the DT cord-006870-f5w6fw6q 5815 7 initial initial JJ cord-006870-f5w6fw6q 5815 8 program program NN cord-006870-f5w6fw6q 5815 9 we -PRON- PRP cord-006870-f5w6fw6q 5815 10 are be VBP cord-006870-f5w6fw6q 5815 11 currently currently RB cord-006870-f5w6fw6q 5815 12 in in IN cord-006870-f5w6fw6q 5815 13 the the DT cord-006870-f5w6fw6q 5815 14 process process NN cord-006870-f5w6fw6q 5815 15 of of IN cord-006870-f5w6fw6q 5815 16 extending extend VBG cord-006870-f5w6fw6q 5815 17 the the DT cord-006870-f5w6fw6q 5815 18 virtual virtual JJ cord-006870-f5w6fw6q 5815 19 consult consult NN cord-006870-f5w6fw6q 5815 20 service service NN cord-006870-f5w6fw6q 5815 21 to to IN cord-006870-f5w6fw6q 5815 22 various various JJ cord-006870-f5w6fw6q 5815 23 community community NN cord-006870-f5w6fw6q 5815 24 hospitals hospital NNS cord-006870-f5w6fw6q 5815 25 ' ' POS cord-006870-f5w6fw6q 5815 26 EDs EDs NNP cord-006870-f5w6fw6q 5815 27 / / SYM cord-006870-f5w6fw6q 5815 28 ICUs ICUs NNP cord-006870-f5w6fw6q 5815 29 to to TO cord-006870-f5w6fw6q 5815 30 improve improve VB cord-006870-f5w6fw6q 5815 31 outcomes outcome NNS cord-006870-f5w6fw6q 5815 32 for for IN cord-006870-f5w6fw6q 5815 33 patients patient NNS cord-006870-f5w6fw6q 5815 34 who who WP cord-006870-f5w6fw6q 5815 35 would would MD cord-006870-f5w6fw6q 5815 36 benefit benefit VB cord-006870-f5w6fw6q 5815 37 from from IN cord-006870-f5w6fw6q 5815 38 neurocritical neurocritical NNP cord-006870-f5w6fw6q 5815 39 care care NN cord-006870-f5w6fw6q 5815 40 services service NNS cord-006870-f5w6fw6q 5815 41 . . . cord-006870-f5w6fw6q 5816 1 Hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 5816 2 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5816 3 is be VBZ cord-006870-f5w6fw6q 5816 4 a a DT cord-006870-f5w6fw6q 5816 5 potentially potentially RB cord-006870-f5w6fw6q 5816 6 life life NN cord-006870-f5w6fw6q 5816 7 - - HYPH cord-006870-f5w6fw6q 5816 8 threatening threaten VBG cord-006870-f5w6fw6q 5816 9 manifestation manifestation NN cord-006870-f5w6fw6q 5816 10 of of IN cord-006870-f5w6fw6q 5816 11 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 5816 12 , , , cord-006870-f5w6fw6q 5816 13 It -PRON- PRP cord-006870-f5w6fw6q 5816 14 is be VBZ cord-006870-f5w6fw6q 5816 15 usually usually RB cord-006870-f5w6fw6q 5816 16 caused cause VBN cord-006870-f5w6fw6q 5816 17 by by IN cord-006870-f5w6fw6q 5816 18 metabolic metabolic JJ cord-006870-f5w6fw6q 5816 19 change change NN cord-006870-f5w6fw6q 5816 20 , , , cord-006870-f5w6fw6q 5816 21 hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 5816 22 agents agent NNS cord-006870-f5w6fw6q 5816 23 , , , cord-006870-f5w6fw6q 5816 24 and and CC cord-006870-f5w6fw6q 5816 25 malignancy malignancy NN cord-006870-f5w6fw6q 5816 26 . . . cord-006870-f5w6fw6q 5817 1 Here here RB cord-006870-f5w6fw6q 5817 2 , , , cord-006870-f5w6fw6q 5817 3 we -PRON- PRP cord-006870-f5w6fw6q 5817 4 report report VBP cord-006870-f5w6fw6q 5817 5 a a DT cord-006870-f5w6fw6q 5817 6 patient patient NN cord-006870-f5w6fw6q 5817 7 with with IN cord-006870-f5w6fw6q 5817 8 hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 5817 9 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5817 10 caused cause VBN cord-006870-f5w6fw6q 5817 11 by by IN cord-006870-f5w6fw6q 5817 12 sleeve sleeve NN cord-006870-f5w6fw6q 5817 13 gastrectomy gastrectomy NN cord-006870-f5w6fw6q 5818 1 A a DT cord-006870-f5w6fw6q 5818 2 34-year 34-year JJ cord-006870-f5w6fw6q 5818 3 - - HYPH cord-006870-f5w6fw6q 5818 4 old old JJ cord-006870-f5w6fw6q 5818 5 woman woman NN cord-006870-f5w6fw6q 5818 6 was be VBD cord-006870-f5w6fw6q 5818 7 admitted admit VBN cord-006870-f5w6fw6q 5818 8 due due IN cord-006870-f5w6fw6q 5818 9 to to IN cord-006870-f5w6fw6q 5818 10 unconsciousness unconsciousness NN cord-006870-f5w6fw6q 5818 11 of of IN cord-006870-f5w6fw6q 5818 12 acute acute JJ cord-006870-f5w6fw6q 5818 13 onset onset NN cord-006870-f5w6fw6q 5818 14 . . . cord-006870-f5w6fw6q 5819 1 She -PRON- PRP cord-006870-f5w6fw6q 5819 2 showed show VBD cord-006870-f5w6fw6q 5819 3 normal normal JJ cord-006870-f5w6fw6q 5819 4 corneal corneal JJ cord-006870-f5w6fw6q 5819 5 and and CC cord-006870-f5w6fw6q 5819 6 vestibulo vestibulo JJ cord-006870-f5w6fw6q 5819 7 - - HYPH cord-006870-f5w6fw6q 5819 8 ocular ocular JJ cord-006870-f5w6fw6q 5819 9 reflex reflex NN cord-006870-f5w6fw6q 5819 10 but but CC cord-006870-f5w6fw6q 5819 11 sluggish sluggish JJ cord-006870-f5w6fw6q 5819 12 pupil pupil NN cord-006870-f5w6fw6q 5820 1 light light JJ cord-006870-f5w6fw6q 5820 2 reflex reflex NNP cord-006870-f5w6fw6q 5820 3 and and CC cord-006870-f5w6fw6q 5820 4 decerebrated decerebrated JJ cord-006870-f5w6fw6q 5820 5 posture posture NN cord-006870-f5w6fw6q 5820 6 by by IN cord-006870-f5w6fw6q 5820 7 painful painful JJ cord-006870-f5w6fw6q 5820 8 stimulation stimulation NN cord-006870-f5w6fw6q 5820 9 . . . cord-006870-f5w6fw6q 5821 1 She -PRON- PRP cord-006870-f5w6fw6q 5821 2 has have VBZ cord-006870-f5w6fw6q 5821 3 taken take VBN cord-006870-f5w6fw6q 5821 4 severe severe JJ cord-006870-f5w6fw6q 5821 5 medications medication NNS cord-006870-f5w6fw6q 5821 6 for for IN cord-006870-f5w6fw6q 5821 7 weight weight NN cord-006870-f5w6fw6q 5821 8 control control NN cord-006870-f5w6fw6q 5821 9 including include VBG cord-006870-f5w6fw6q 5821 10 orthosiphon orthosiphon NNP cord-006870-f5w6fw6q 5821 11 powder powder NN cord-006870-f5w6fw6q 5821 12 and and CC cord-006870-f5w6fw6q 5821 13 hydrochlorothiazide hydrochlorothiazide NN cord-006870-f5w6fw6q 5821 14 after after IN cord-006870-f5w6fw6q 5821 15 bariatric bariatric JJ cord-006870-f5w6fw6q 5821 16 surgery surgery NN cord-006870-f5w6fw6q 5821 17 . . . cord-006870-f5w6fw6q 5822 1 Laboratory laboratory NN cord-006870-f5w6fw6q 5822 2 studies study NNS cord-006870-f5w6fw6q 5822 3 showed show VBD cord-006870-f5w6fw6q 5822 4 significantly significantly RB cord-006870-f5w6fw6q 5822 5 low low JJ cord-006870-f5w6fw6q 5822 6 blood blood NN cord-006870-f5w6fw6q 5822 7 glucose glucose NN cord-006870-f5w6fw6q 5822 8 level level NN cord-006870-f5w6fw6q 5822 9 ( ( -LRB- cord-006870-f5w6fw6q 5822 10 13mg 13mg NN cord-006870-f5w6fw6q 5822 11 / / SYM cord-006870-f5w6fw6q 5822 12 dL dl NN cord-006870-f5w6fw6q 5822 13 ) ) -RRB- cord-006870-f5w6fw6q 5822 14 with with IN cord-006870-f5w6fw6q 5822 15 normal normal JJ cord-006870-f5w6fw6q 5822 16 liver liver NN cord-006870-f5w6fw6q 5822 17 enzyme enzyme NN cord-006870-f5w6fw6q 5822 18 and and CC cord-006870-f5w6fw6q 5822 19 creatinine creatinine NN cord-006870-f5w6fw6q 5822 20 . . . cord-006870-f5w6fw6q 5823 1 There there EX cord-006870-f5w6fw6q 5823 2 was be VBD cord-006870-f5w6fw6q 5823 3 no no DT cord-006870-f5w6fw6q 5823 4 evidence evidence NN cord-006870-f5w6fw6q 5823 5 of of IN cord-006870-f5w6fw6q 5823 6 adrenal adrenal JJ cord-006870-f5w6fw6q 5823 7 insufficiency insufficiency NN cord-006870-f5w6fw6q 5823 8 . . . cord-006870-f5w6fw6q 5824 1 Electroencephalography electroencephalography NN cord-006870-f5w6fw6q 5824 2 showed show VBD cord-006870-f5w6fw6q 5824 3 no no DT cord-006870-f5w6fw6q 5824 4 epileptiform epileptiform NN cord-006870-f5w6fw6q 5824 5 discharge discharge NN cord-006870-f5w6fw6q 5824 6 . . . cord-006870-f5w6fw6q 5825 1 Initial initial JJ cord-006870-f5w6fw6q 5825 2 and and CC cord-006870-f5w6fw6q 5825 3 follow follow VB cord-006870-f5w6fw6q 5825 4 - - HYPH cord-006870-f5w6fw6q 5825 5 up up RP cord-006870-f5w6fw6q 5825 6 brain brain NN cord-006870-f5w6fw6q 5825 7 magnetic magnetic JJ cord-006870-f5w6fw6q 5825 8 resonance resonance NN cord-006870-f5w6fw6q 5825 9 imaging imaging NN cord-006870-f5w6fw6q 5825 10 revealed reveal VBD cord-006870-f5w6fw6q 5825 11 diffuse diffuse JJ cord-006870-f5w6fw6q 5825 12 high high JJ cord-006870-f5w6fw6q 5825 13 signal signal NN cord-006870-f5w6fw6q 5825 14 intensity intensity NN cord-006870-f5w6fw6q 5825 15 on on IN cord-006870-f5w6fw6q 5825 16 white white JJ cord-006870-f5w6fw6q 5825 17 matter matter NN cord-006870-f5w6fw6q 5825 18 expanded expand VBN cord-006870-f5w6fw6q 5825 19 to to IN cord-006870-f5w6fw6q 5825 20 cortex cortex NNP cord-006870-f5w6fw6q 5825 21 , , , cord-006870-f5w6fw6q 5825 22 corpus corpus NNP cord-006870-f5w6fw6q 5825 23 callosum callosum NN cord-006870-f5w6fw6q 5825 24 and and CC cord-006870-f5w6fw6q 5825 25 posterior posterior JJ cord-006870-f5w6fw6q 5825 26 limb limb NN cord-006870-f5w6fw6q 5825 27 of of IN cord-006870-f5w6fw6q 5825 28 the the DT cord-006870-f5w6fw6q 5825 29 left left JJ cord-006870-f5w6fw6q 5825 30 internal internal JJ cord-006870-f5w6fw6q 5825 31 capsule capsule NN cord-006870-f5w6fw6q 5825 32 , , , cord-006870-f5w6fw6q 5825 33 suggesting suggest VBG cord-006870-f5w6fw6q 5825 34 hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 5825 35 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5825 36 . . . cord-006870-f5w6fw6q 5826 1 In in IN cord-006870-f5w6fw6q 5826 2 abdomen abdomen JJ cord-006870-f5w6fw6q 5826 3 - - HYPH cord-006870-f5w6fw6q 5826 4 pelvic pelvic JJ cord-006870-f5w6fw6q 5826 5 CT CT NNP cord-006870-f5w6fw6q 5826 6 , , , cord-006870-f5w6fw6q 5826 7 there there EX cord-006870-f5w6fw6q 5826 8 is be VBZ cord-006870-f5w6fw6q 5826 9 no no DT cord-006870-f5w6fw6q 5826 10 mass mass JJ cord-006870-f5w6fw6q 5826 11 lesion lesion NN cord-006870-f5w6fw6q 5826 12 like like IN cord-006870-f5w6fw6q 5826 13 carcinomas carcinoma NNS cord-006870-f5w6fw6q 5826 14 or or CC cord-006870-f5w6fw6q 5826 15 insulinoma insulinoma NN cord-006870-f5w6fw6q 5826 16 . . . cord-006870-f5w6fw6q 5827 1 The the DT cord-006870-f5w6fw6q 5827 2 clinical clinical JJ cord-006870-f5w6fw6q 5827 3 diagnosis diagnosis NN cord-006870-f5w6fw6q 5827 4 of of IN cord-006870-f5w6fw6q 5827 5 hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 5827 6 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5827 7 followed follow VBN cord-006870-f5w6fw6q 5827 8 by by IN cord-006870-f5w6fw6q 5827 9 sleeve sleeve NN cord-006870-f5w6fw6q 5827 10 gastrectomy gastrectomy NN cord-006870-f5w6fw6q 5827 11 was be VBD cord-006870-f5w6fw6q 5827 12 made make VBN cord-006870-f5w6fw6q 5827 13 by by IN cord-006870-f5w6fw6q 5827 14 given give VBN cord-006870-f5w6fw6q 5827 15 history history NN cord-006870-f5w6fw6q 5827 16 of of IN cord-006870-f5w6fw6q 5827 17 bariatric bariatric JJ cord-006870-f5w6fw6q 5827 18 surgery surgery NN cord-006870-f5w6fw6q 5827 19 and and CC cord-006870-f5w6fw6q 5827 20 the the DT cord-006870-f5w6fw6q 5827 21 lack lack NN cord-006870-f5w6fw6q 5827 22 of of IN cord-006870-f5w6fw6q 5827 23 evidence evidence NN cord-006870-f5w6fw6q 5827 24 of of IN cord-006870-f5w6fw6q 5827 25 hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 5827 26 agent agent NN cord-006870-f5w6fw6q 5827 27 overdose overdose NN cord-006870-f5w6fw6q 5827 28 , , , cord-006870-f5w6fw6q 5827 29 adrenal adrenal JJ cord-006870-f5w6fw6q 5827 30 insufficiency insufficiency NN cord-006870-f5w6fw6q 5827 31 , , , cord-006870-f5w6fw6q 5827 32 endogenous endogenous JJ cord-006870-f5w6fw6q 5827 33 hyperinsulinism hyperinsulinism NN cord-006870-f5w6fw6q 5827 34 or or CC cord-006870-f5w6fw6q 5827 35 malignancy malignancy NN cord-006870-f5w6fw6q 5827 36 . . . cord-006870-f5w6fw6q 5828 1 There there EX cord-006870-f5w6fw6q 5828 2 are be VBP cord-006870-f5w6fw6q 5828 3 several several JJ cord-006870-f5w6fw6q 5828 4 hypotheses hypothesis NNS cord-006870-f5w6fw6q 5828 5 that that WDT cord-006870-f5w6fw6q 5828 6 sleeve sleeve VBP cord-006870-f5w6fw6q 5828 7 gastrectomy gastrectomy NN cord-006870-f5w6fw6q 5828 8 can can MD cord-006870-f5w6fw6q 5828 9 encourage encourage VB cord-006870-f5w6fw6q 5828 10 hypertrophy hypertrophy NN cord-006870-f5w6fw6q 5828 11 of of IN cord-006870-f5w6fw6q 5828 12 beta beta NN cord-006870-f5w6fw6q 5828 13 cells cell NNS cord-006870-f5w6fw6q 5828 14 , , , cord-006870-f5w6fw6q 5828 15 hypersecretion hypersecretion NN cord-006870-f5w6fw6q 5828 16 of of IN cord-006870-f5w6fw6q 5828 17 glucagon glucagon NNP cord-006870-f5w6fw6q 5828 18 - - HYPH cord-006870-f5w6fw6q 5828 19 like like JJ cord-006870-f5w6fw6q 5828 20 peptide peptide NN cord-006870-f5w6fw6q 5828 21 , , , cord-006870-f5w6fw6q 5828 22 glucagon glucagon NN cord-006870-f5w6fw6q 5828 23 abnormality abnormality NN cord-006870-f5w6fw6q 5828 24 and and CC cord-006870-f5w6fw6q 5828 25 increased increase VBN cord-006870-f5w6fw6q 5828 26 insulin insulin NN cord-006870-f5w6fw6q 5828 27 sensitivity sensitivity NN cord-006870-f5w6fw6q 5828 28 , , , cord-006870-f5w6fw6q 5828 29 that that WDT cord-006870-f5w6fw6q 5828 30 may may MD cord-006870-f5w6fw6q 5828 31 induce induce VB cord-006870-f5w6fw6q 5828 32 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 5828 33 . . . cord-006870-f5w6fw6q 5829 1 We -PRON- PRP cord-006870-f5w6fw6q 5829 2 suggest suggest VBP cord-006870-f5w6fw6q 5829 3 that that IN cord-006870-f5w6fw6q 5829 4 clinicians clinician NNS cord-006870-f5w6fw6q 5829 5 should should MD cord-006870-f5w6fw6q 5829 6 consider consider VB cord-006870-f5w6fw6q 5829 7 sleeve sleeve NN cord-006870-f5w6fw6q 5829 8 gastrectomy gastrectomy NN cord-006870-f5w6fw6q 5829 9 itself -PRON- PRP cord-006870-f5w6fw6q 5829 10 as as IN cord-006870-f5w6fw6q 5829 11 a a DT cord-006870-f5w6fw6q 5829 12 possible possible JJ cord-006870-f5w6fw6q 5829 13 cause cause NN cord-006870-f5w6fw6q 5829 14 of of IN cord-006870-f5w6fw6q 5829 15 profound profound JJ cord-006870-f5w6fw6q 5829 16 hypoglycemia hypoglycemia NN cord-006870-f5w6fw6q 5829 17 Pulmonary pulmonary JJ cord-006870-f5w6fw6q 5829 18 embolism embolism NN cord-006870-f5w6fw6q 5829 19 ( ( -LRB- cord-006870-f5w6fw6q 5829 20 PE PE NNP cord-006870-f5w6fw6q 5829 21 ) ) -RRB- cord-006870-f5w6fw6q 5829 22 is be VBZ cord-006870-f5w6fw6q 5829 23 a a DT cord-006870-f5w6fw6q 5829 24 fatal fatal JJ cord-006870-f5w6fw6q 5829 25 complication complication NN cord-006870-f5w6fw6q 5829 26 in in IN cord-006870-f5w6fw6q 5829 27 neurological neurological JJ cord-006870-f5w6fw6q 5829 28 conditions condition NNS cord-006870-f5w6fw6q 5829 29 with with IN cord-006870-f5w6fw6q 5829 30 plegic plegic JJ cord-006870-f5w6fw6q 5829 31 extremities extremity NNS cord-006870-f5w6fw6q 5829 32 . . . cord-006870-f5w6fw6q 5830 1 Clinical clinical JJ cord-006870-f5w6fw6q 5830 2 presentations presentation NNS cord-006870-f5w6fw6q 5830 3 and and CC cord-006870-f5w6fw6q 5830 4 supportive supportive JJ cord-006870-f5w6fw6q 5830 5 testing testing NN cord-006870-f5w6fw6q 5830 6 can can MD cord-006870-f5w6fw6q 5830 7 be be VB cord-006870-f5w6fw6q 5830 8 variable variable JJ cord-006870-f5w6fw6q 5830 9 . . . cord-006870-f5w6fw6q 5831 1 We -PRON- PRP cord-006870-f5w6fw6q 5831 2 present present VBP cord-006870-f5w6fw6q 5831 3 a a DT cord-006870-f5w6fw6q 5831 4 case case NN cord-006870-f5w6fw6q 5831 5 of of IN cord-006870-f5w6fw6q 5831 6 PE PE NNP cord-006870-f5w6fw6q 5831 7 which which WDT cord-006870-f5w6fw6q 5831 8 presented present VBD cord-006870-f5w6fw6q 5831 9 with with IN cord-006870-f5w6fw6q 5831 10 ST ST NNP cord-006870-f5w6fw6q 5831 11 segment segment NN cord-006870-f5w6fw6q 5831 12 elevations elevation NNS cord-006870-f5w6fw6q 5831 13 2 2 CD cord-006870-f5w6fw6q 5831 14 weeks week NNS cord-006870-f5w6fw6q 5831 15 after after IN cord-006870-f5w6fw6q 5831 16 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5831 17 intracerebral intracerebral JJ cord-006870-f5w6fw6q 5831 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5831 19 ( ( -LRB- cord-006870-f5w6fw6q 5831 20 sICH sich NN cord-006870-f5w6fw6q 5831 21 ) ) -RRB- cord-006870-f5w6fw6q 5831 22 . . . cord-006870-f5w6fw6q 5832 1 Case case NN cord-006870-f5w6fw6q 5832 2 report report NN cord-006870-f5w6fw6q 5832 3 and and CC cord-006870-f5w6fw6q 5832 4 review review NN cord-006870-f5w6fw6q 5832 5 of of IN cord-006870-f5w6fw6q 5832 6 the the DT cord-006870-f5w6fw6q 5832 7 literature literature NN cord-006870-f5w6fw6q 5833 1 We -PRON- PRP cord-006870-f5w6fw6q 5833 2 present present VBP cord-006870-f5w6fw6q 5833 3 a a DT cord-006870-f5w6fw6q 5833 4 case case NN cord-006870-f5w6fw6q 5833 5 of of IN cord-006870-f5w6fw6q 5833 6 a a DT cord-006870-f5w6fw6q 5833 7 68 68 CD cord-006870-f5w6fw6q 5833 8 year year NN cord-006870-f5w6fw6q 5833 9 old old JJ cord-006870-f5w6fw6q 5833 10 female female NN cord-006870-f5w6fw6q 5833 11 with with IN cord-006870-f5w6fw6q 5833 12 a a DT cord-006870-f5w6fw6q 5833 13 history history NN cord-006870-f5w6fw6q 5833 14 of of IN cord-006870-f5w6fw6q 5833 15 a a DT cord-006870-f5w6fw6q 5833 16 recent recent JJ cord-006870-f5w6fw6q 5833 17 sICH sich NN cord-006870-f5w6fw6q 5833 18 with with IN cord-006870-f5w6fw6q 5833 19 resultant resultant JJ cord-006870-f5w6fw6q 5833 20 left leave VBN cord-006870-f5w6fw6q 5833 21 hemiplegia hemiplegia NN cord-006870-f5w6fw6q 5833 22 who who WP cord-006870-f5w6fw6q 5833 23 presented present VBD cord-006870-f5w6fw6q 5833 24 with with IN cord-006870-f5w6fw6q 5833 25 a a DT cord-006870-f5w6fw6q 5833 26 syncopal syncopal JJ cord-006870-f5w6fw6q 5833 27 episode episode NN cord-006870-f5w6fw6q 5833 28 and and CC cord-006870-f5w6fw6q 5833 29 chest chest NN cord-006870-f5w6fw6q 5833 30 pain pain NN cord-006870-f5w6fw6q 5833 31 . . . cord-006870-f5w6fw6q 5834 1 On on IN cord-006870-f5w6fw6q 5834 2 physical physical JJ cord-006870-f5w6fw6q 5834 3 examination examination NN cord-006870-f5w6fw6q 5834 4 , , , cord-006870-f5w6fw6q 5834 5 she -PRON- PRP cord-006870-f5w6fw6q 5834 6 was be VBD cord-006870-f5w6fw6q 5834 7 noted note VBN cord-006870-f5w6fw6q 5834 8 to to TO cord-006870-f5w6fw6q 5834 9 be be VB cord-006870-f5w6fw6q 5834 10 tachypneic tachypneic NNP cord-006870-f5w6fw6q 5834 11 and and CC cord-006870-f5w6fw6q 5834 12 tachycardic tachycardic JJ cord-006870-f5w6fw6q 5834 13 with with IN cord-006870-f5w6fw6q 5834 14 an an DT cord-006870-f5w6fw6q 5834 15 unchanged unchanged JJ cord-006870-f5w6fw6q 5834 16 neurological neurological JJ cord-006870-f5w6fw6q 5834 17 exam exam NN cord-006870-f5w6fw6q 5834 18 . . . cord-006870-f5w6fw6q 5834 19 _SP cord-006870-f5w6fw6q 5835 1 Pulmonary pulmonary JJ cord-006870-f5w6fw6q 5835 2 embolism embolism NN cord-006870-f5w6fw6q 5835 3 can can MD cord-006870-f5w6fw6q 5835 4 present present VB cord-006870-f5w6fw6q 5835 5 with with IN cord-006870-f5w6fw6q 5835 6 a a DT cord-006870-f5w6fw6q 5835 7 variety variety NN cord-006870-f5w6fw6q 5835 8 of of IN cord-006870-f5w6fw6q 5835 9 EKG EKG NNP cord-006870-f5w6fw6q 5835 10 abnormalities abnormality NNS cord-006870-f5w6fw6q 5835 11 including include VBG cord-006870-f5w6fw6q 5835 12 ST ST NNP cord-006870-f5w6fw6q 5835 13 elevations elevation NNS cord-006870-f5w6fw6q 5835 14 after after IN cord-006870-f5w6fw6q 5835 15 sICH sich NN cord-006870-f5w6fw6q 5835 16 and and CC cord-006870-f5w6fw6q 5835 17 the the DT cord-006870-f5w6fw6q 5835 18 treating treat VBG cord-006870-f5w6fw6q 5835 19 physician physician NN cord-006870-f5w6fw6q 5835 20 should should MD cord-006870-f5w6fw6q 5835 21 be be VB cord-006870-f5w6fw6q 5835 22 aware aware JJ cord-006870-f5w6fw6q 5835 23 of of IN cord-006870-f5w6fw6q 5835 24 these these DT cord-006870-f5w6fw6q 5835 25 idiosyncrasies idiosyncrasy NNS cord-006870-f5w6fw6q 5835 26 . . . cord-006870-f5w6fw6q 5836 1 Anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5836 2 should should MD cord-006870-f5w6fw6q 5836 3 be be VB cord-006870-f5w6fw6q 5836 4 cautiously cautiously RB cord-006870-f5w6fw6q 5836 5 initiated initiate VBN cord-006870-f5w6fw6q 5836 6 in in IN cord-006870-f5w6fw6q 5836 7 such such JJ cord-006870-f5w6fw6q 5836 8 cases case NNS cord-006870-f5w6fw6q 5836 9 . . . cord-006870-f5w6fw6q 5837 1 Infectious infectious JJ cord-006870-f5w6fw6q 5837 2 intracranial intracranial JJ cord-006870-f5w6fw6q 5837 3 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5837 4 ( ( -LRB- cord-006870-f5w6fw6q 5837 5 IIA IIA NNP cord-006870-f5w6fw6q 5837 6 ) ) -RRB- cord-006870-f5w6fw6q 5837 7 are be VBP cord-006870-f5w6fw6q 5837 8 rare rare JJ cord-006870-f5w6fw6q 5837 9 neurovascular neurovascular JJ cord-006870-f5w6fw6q 5837 10 lesions lesion NNS cord-006870-f5w6fw6q 5837 11 associated associate VBN cord-006870-f5w6fw6q 5837 12 with with IN cord-006870-f5w6fw6q 5837 13 infective infective JJ cord-006870-f5w6fw6q 5837 14 endocarditis endocarditis NN cord-006870-f5w6fw6q 5837 15 . . . cord-006870-f5w6fw6q 5838 1 We -PRON- PRP cord-006870-f5w6fw6q 5838 2 present present VBP cord-006870-f5w6fw6q 5838 3 a a DT cord-006870-f5w6fw6q 5838 4 case case NN cord-006870-f5w6fw6q 5838 5 of of IN cord-006870-f5w6fw6q 5838 6 a a DT cord-006870-f5w6fw6q 5838 7 large large JJ cord-006870-f5w6fw6q 5838 8 IIA IIA NNP cord-006870-f5w6fw6q 5838 9 which which WDT cord-006870-f5w6fw6q 5838 10 developed develop VBD cord-006870-f5w6fw6q 5838 11 within within IN cord-006870-f5w6fw6q 5838 12 24 24 CD cord-006870-f5w6fw6q 5838 13 hours hour NNS cord-006870-f5w6fw6q 5838 14 of of IN cord-006870-f5w6fw6q 5838 15 a a DT cord-006870-f5w6fw6q 5838 16 negative negative JJ cord-006870-f5w6fw6q 5838 17 CT CT NNP cord-006870-f5w6fw6q 5838 18 angiogram angiogram NN cord-006870-f5w6fw6q 5838 19 and and CC cord-006870-f5w6fw6q 5838 20 ruptured rupture VBD cord-006870-f5w6fw6q 5838 21 despite despite IN cord-006870-f5w6fw6q 5838 22 4 4 CD cord-006870-f5w6fw6q 5838 23 weeks week NNS cord-006870-f5w6fw6q 5838 24 of of IN cord-006870-f5w6fw6q 5838 25 appropriate appropriate JJ cord-006870-f5w6fw6q 5838 26 antibiotic antibiotic JJ cord-006870-f5w6fw6q 5838 27 treatment treatment NN cord-006870-f5w6fw6q 5838 28 . . . cord-006870-f5w6fw6q 5839 1 A a DT cord-006870-f5w6fw6q 5839 2 66 66 CD cord-006870-f5w6fw6q 5839 3 year year NN cord-006870-f5w6fw6q 5839 4 - - HYPH cord-006870-f5w6fw6q 5839 5 old old JJ cord-006870-f5w6fw6q 5839 6 woman woman NN cord-006870-f5w6fw6q 5839 7 presented present VBN cord-006870-f5w6fw6q 5839 8 with with IN cord-006870-f5w6fw6q 5839 9 fevers fever NNS cord-006870-f5w6fw6q 5839 10 and and CC cord-006870-f5w6fw6q 5839 11 malaise malaise NN cord-006870-f5w6fw6q 5839 12 . . . cord-006870-f5w6fw6q 5840 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 5840 2 initial initial JJ cord-006870-f5w6fw6q 5840 3 workup workup NN cord-006870-f5w6fw6q 5840 4 revealed reveal VBD cord-006870-f5w6fw6q 5840 5 an an DT cord-006870-f5w6fw6q 5840 6 aortic aortic JJ cord-006870-f5w6fw6q 5840 7 valve valve NN cord-006870-f5w6fw6q 5840 8 mass mass NN cord-006870-f5w6fw6q 5840 9 and and CC cord-006870-f5w6fw6q 5840 10 blood blood NN cord-006870-f5w6fw6q 5840 11 cultures culture NNS cord-006870-f5w6fw6q 5840 12 grew grow VBD cord-006870-f5w6fw6q 5840 13 out out RP cord-006870-f5w6fw6q 5840 14 Streptococcus streptococcus NN cord-006870-f5w6fw6q 5840 15 . . . cord-006870-f5w6fw6q 5841 1 Three three CD cord-006870-f5w6fw6q 5841 2 days day NNS cord-006870-f5w6fw6q 5841 3 after after IN cord-006870-f5w6fw6q 5841 4 intravenous intravenous JJ cord-006870-f5w6fw6q 5841 5 penicillin penicillin NN cord-006870-f5w6fw6q 5841 6 therapy therapy NN cord-006870-f5w6fw6q 5841 7 was be VBD cord-006870-f5w6fw6q 5841 8 initiated initiate VBN cord-006870-f5w6fw6q 5841 9 for for IN cord-006870-f5w6fw6q 5841 10 bacterial bacterial JJ cord-006870-f5w6fw6q 5841 11 endocarditis endocarditis NN cord-006870-f5w6fw6q 5841 12 , , , cord-006870-f5w6fw6q 5841 13 she -PRON- PRP cord-006870-f5w6fw6q 5841 14 developed develop VBD cord-006870-f5w6fw6q 5841 15 a a DT cord-006870-f5w6fw6q 5841 16 new new JJ cord-006870-f5w6fw6q 5841 17 headache headache NN cord-006870-f5w6fw6q 5841 18 and and CC cord-006870-f5w6fw6q 5841 19 right right JJ cord-006870-f5w6fw6q 5841 20 hemianopsia hemianopsia NNP cord-006870-f5w6fw6q 5841 21 . . . cord-006870-f5w6fw6q 5842 1 A a DT cord-006870-f5w6fw6q 5842 2 head head NN cord-006870-f5w6fw6q 5842 3 CT CT NNP cord-006870-f5w6fw6q 5842 4 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5842 5 a a DT cord-006870-f5w6fw6q 5842 6 left left JJ cord-006870-f5w6fw6q 5842 7 occipital occipital JJ cord-006870-f5w6fw6q 5842 8 lobe lobe NN cord-006870-f5w6fw6q 5842 9 stroke stroke NN cord-006870-f5w6fw6q 5842 10 with with IN cord-006870-f5w6fw6q 5842 11 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 5842 12 transformation transformation NN cord-006870-f5w6fw6q 5842 13 . . . cord-006870-f5w6fw6q 5843 1 Further further JJ cord-006870-f5w6fw6q 5843 2 workup workup NN cord-006870-f5w6fw6q 5843 3 with with IN cord-006870-f5w6fw6q 5843 4 CT CT NNP cord-006870-f5w6fw6q 5843 5 angiography angiography NN cord-006870-f5w6fw6q 5843 6 revealed reveal VBD cord-006870-f5w6fw6q 5843 7 a a DT cord-006870-f5w6fw6q 5843 8 5 5 CD cord-006870-f5w6fw6q 5843 9 mm mm NN cord-006870-f5w6fw6q 5843 10 outpouching outpouche VBG cord-006870-f5w6fw6q 5843 11 along along IN cord-006870-f5w6fw6q 5843 12 of of IN cord-006870-f5w6fw6q 5843 13 the the DT cord-006870-f5w6fw6q 5843 14 distal distal JJ cord-006870-f5w6fw6q 5843 15 branch branch NN cord-006870-f5w6fw6q 5843 16 of of IN cord-006870-f5w6fw6q 5843 17 the the DT cord-006870-f5w6fw6q 5843 18 left left JJ cord-006870-f5w6fw6q 5843 19 PCA PCA NNP cord-006870-f5w6fw6q 5843 20 , , , cord-006870-f5w6fw6q 5843 21 consistent consistent JJ cord-006870-f5w6fw6q 5843 22 with with IN cord-006870-f5w6fw6q 5843 23 an an DT cord-006870-f5w6fw6q 5843 24 infectious infectious JJ cord-006870-f5w6fw6q 5843 25 intracranial intracranial JJ cord-006870-f5w6fw6q 5843 26 aneurysm aneurysm NN cord-006870-f5w6fw6q 5843 27 . . . cord-006870-f5w6fw6q 5844 1 On on IN cord-006870-f5w6fw6q 5844 2 repeat repeat NN cord-006870-f5w6fw6q 5844 3 imaging imaging NN cord-006870-f5w6fw6q 5844 4 , , , cord-006870-f5w6fw6q 5844 5 this this DT cord-006870-f5w6fw6q 5844 6 aneurysm aneurysm NN cord-006870-f5w6fw6q 5844 7 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5844 8 growth growth NN cord-006870-f5w6fw6q 5844 9 despite despite IN cord-006870-f5w6fw6q 5844 10 medical medical JJ cord-006870-f5w6fw6q 5844 11 treatment treatment NN cord-006870-f5w6fw6q 5844 12 , , , cord-006870-f5w6fw6q 5844 13 and and CC cord-006870-f5w6fw6q 5844 14 required require VBN cord-006870-f5w6fw6q 5844 15 coil coil NN cord-006870-f5w6fw6q 5844 16 embolization embolization NN cord-006870-f5w6fw6q 5844 17 / / SYM cord-006870-f5w6fw6q 5844 18 occlusion occlusion NN cord-006870-f5w6fw6q 5844 19 . . . cord-006870-f5w6fw6q 5845 1 Aortic aortic JJ cord-006870-f5w6fw6q 5845 2 valve valve NN cord-006870-f5w6fw6q 5845 3 replacement replacement NN cord-006870-f5w6fw6q 5845 4 was be VBD cord-006870-f5w6fw6q 5845 5 planned plan VBN cord-006870-f5w6fw6q 5845 6 after after IN cord-006870-f5w6fw6q 5845 7 4 4 CD cord-006870-f5w6fw6q 5845 8 weeks week NNS cord-006870-f5w6fw6q 5845 9 of of IN cord-006870-f5w6fw6q 5845 10 antibiotic antibiotic JJ cord-006870-f5w6fw6q 5845 11 therapy therapy NN cord-006870-f5w6fw6q 5845 12 because because IN cord-006870-f5w6fw6q 5845 13 of of IN cord-006870-f5w6fw6q 5845 14 continued continued JJ cord-006870-f5w6fw6q 5845 15 severe severe JJ cord-006870-f5w6fw6q 5845 16 aortic aortic JJ cord-006870-f5w6fw6q 5845 17 insufficiency insufficiency NN cord-006870-f5w6fw6q 5845 18 and and CC cord-006870-f5w6fw6q 5845 19 persistent persistent JJ cord-006870-f5w6fw6q 5845 20 valve valve NN cord-006870-f5w6fw6q 5845 21 vegetation vegetation NN cord-006870-f5w6fw6q 5845 22 . . . cord-006870-f5w6fw6q 5846 1 On on IN cord-006870-f5w6fw6q 5846 2 the the DT cord-006870-f5w6fw6q 5846 3 day day NN cord-006870-f5w6fw6q 5846 4 of of IN cord-006870-f5w6fw6q 5846 5 surgery surgery NN cord-006870-f5w6fw6q 5846 6 , , , cord-006870-f5w6fw6q 5846 7 she -PRON- PRP cord-006870-f5w6fw6q 5846 8 developed develop VBD cord-006870-f5w6fw6q 5846 9 acute acute JJ cord-006870-f5w6fw6q 5846 10 word word NN cord-006870-f5w6fw6q 5846 11 - - HYPH cord-006870-f5w6fw6q 5846 12 finding find VBG cord-006870-f5w6fw6q 5846 13 difficulty difficulty NN cord-006870-f5w6fw6q 5846 14 followed follow VBN cord-006870-f5w6fw6q 5846 15 by by IN cord-006870-f5w6fw6q 5846 16 a a DT cord-006870-f5w6fw6q 5846 17 rapid rapid JJ cord-006870-f5w6fw6q 5846 18 neurologic neurologic JJ cord-006870-f5w6fw6q 5846 19 deterioration deterioration NN cord-006870-f5w6fw6q 5846 20 resulting result VBG cord-006870-f5w6fw6q 5846 21 in in IN cord-006870-f5w6fw6q 5846 22 coma coma NN cord-006870-f5w6fw6q 5846 23 . . . cord-006870-f5w6fw6q 5847 1 A a DT cord-006870-f5w6fw6q 5847 2 head head NN cord-006870-f5w6fw6q 5847 3 CT CT NNP cord-006870-f5w6fw6q 5847 4 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5847 5 a a DT cord-006870-f5w6fw6q 5847 6 new new JJ cord-006870-f5w6fw6q 5847 7 left left JJ cord-006870-f5w6fw6q 5847 8 frontal frontal JJ cord-006870-f5w6fw6q 5847 9 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 5847 10 and and CC cord-006870-f5w6fw6q 5847 11 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 5847 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5847 13 associated associate VBN cord-006870-f5w6fw6q 5847 14 with with IN cord-006870-f5w6fw6q 5847 15 the the DT cord-006870-f5w6fw6q 5847 16 rupture rupture NN cord-006870-f5w6fw6q 5847 17 of of IN cord-006870-f5w6fw6q 5847 18 an an DT cord-006870-f5w6fw6q 5847 19 11 11 CD cord-006870-f5w6fw6q 5847 20 mm mm CD cord-006870-f5w6fw6q 5847 21 x x SYM cord-006870-f5w6fw6q 5847 22 11 11 CD cord-006870-f5w6fw6q 5847 23 mm mm NN cord-006870-f5w6fw6q 5847 24 irregularly irregularly RB cord-006870-f5w6fw6q 5847 25 shaped shape VBN cord-006870-f5w6fw6q 5847 26 aneurysm aneurysm NN cord-006870-f5w6fw6q 5847 27 in in IN cord-006870-f5w6fw6q 5847 28 the the DT cord-006870-f5w6fw6q 5847 29 region region NN cord-006870-f5w6fw6q 5847 30 of of IN cord-006870-f5w6fw6q 5847 31 the the DT cord-006870-f5w6fw6q 5847 32 left left JJ cord-006870-f5w6fw6q 5847 33 MCA MCA NNP cord-006870-f5w6fw6q 5847 34 bifurcation bifurcation NN cord-006870-f5w6fw6q 5847 35 , , , cord-006870-f5w6fw6q 5847 36 which which WDT cord-006870-f5w6fw6q 5847 37 had have VBD cord-006870-f5w6fw6q 5847 38 been be VBN cord-006870-f5w6fw6q 5847 39 absent absent JJ cord-006870-f5w6fw6q 5847 40 on on IN cord-006870-f5w6fw6q 5847 41 a a DT cord-006870-f5w6fw6q 5847 42 prior prior JJ cord-006870-f5w6fw6q 5847 43 surveillance surveillance NN cord-006870-f5w6fw6q 5847 44 CT CT NNP cord-006870-f5w6fw6q 5847 45 angiography angiography NN cord-006870-f5w6fw6q 5847 46 just just RB cord-006870-f5w6fw6q 5847 47 23 23 CD cord-006870-f5w6fw6q 5847 48 hours hour NNS cord-006870-f5w6fw6q 5847 49 prior prior RB cord-006870-f5w6fw6q 5847 50 . . . cord-006870-f5w6fw6q 5848 1 She -PRON- PRP cord-006870-f5w6fw6q 5848 2 underwent undergo VBD cord-006870-f5w6fw6q 5848 3 emergent emergent JJ cord-006870-f5w6fw6q 5848 4 coil coil NN cord-006870-f5w6fw6q 5848 5 embolization embolization NN cord-006870-f5w6fw6q 5848 6 , , , cord-006870-f5w6fw6q 5848 7 extraventricular extraventricular JJ cord-006870-f5w6fw6q 5848 8 drain drain NN cord-006870-f5w6fw6q 5848 9 placement placement NN cord-006870-f5w6fw6q 5848 10 , , , cord-006870-f5w6fw6q 5848 11 and and CC cord-006870-f5w6fw6q 5848 12 decompressive decompressive JJ cord-006870-f5w6fw6q 5848 13 hemicraniectomy hemicraniectomy NNP cord-006870-f5w6fw6q 5848 14 . . . cord-006870-f5w6fw6q 5849 1 Despite despite IN cord-006870-f5w6fw6q 5849 2 these these DT cord-006870-f5w6fw6q 5849 3 measures measure NNS cord-006870-f5w6fw6q 5849 4 , , , cord-006870-f5w6fw6q 5849 5 her -PRON- PRP$ cord-006870-f5w6fw6q 5849 6 exam exam NN cord-006870-f5w6fw6q 5849 7 did do VBD cord-006870-f5w6fw6q 5849 8 not not RB cord-006870-f5w6fw6q 5849 9 improve improve VB cord-006870-f5w6fw6q 5849 10 . . . cord-006870-f5w6fw6q 5850 1 She -PRON- PRP cord-006870-f5w6fw6q 5850 2 was be VBD cord-006870-f5w6fw6q 5850 3 transitioned transition VBN cord-006870-f5w6fw6q 5850 4 to to TO cord-006870-f5w6fw6q 5850 5 comfort comfort VB cord-006870-f5w6fw6q 5850 6 measures measure NNS cord-006870-f5w6fw6q 5850 7 and and CC cord-006870-f5w6fw6q 5850 8 life life NN cord-006870-f5w6fw6q 5850 9 - - HYPH cord-006870-f5w6fw6q 5850 10 sustaining sustain VBG cord-006870-f5w6fw6q 5850 11 therapies therapy NNS cord-006870-f5w6fw6q 5850 12 were be VBD cord-006870-f5w6fw6q 5850 13 withdrawn withdraw VBN cord-006870-f5w6fw6q 5850 14 . . . cord-006870-f5w6fw6q 5851 1 The the DT cord-006870-f5w6fw6q 5851 2 development development NN cord-006870-f5w6fw6q 5851 3 of of IN cord-006870-f5w6fw6q 5851 4 IIA IIA NNP cord-006870-f5w6fw6q 5851 5 can can MD cord-006870-f5w6fw6q 5851 6 occur occur VB cord-006870-f5w6fw6q 5851 7 despite despite IN cord-006870-f5w6fw6q 5851 8 appropriate appropriate JJ cord-006870-f5w6fw6q 5851 9 medical medical JJ cord-006870-f5w6fw6q 5851 10 treatment treatment NN cord-006870-f5w6fw6q 5851 11 . . . cord-006870-f5w6fw6q 5852 1 These these DT cord-006870-f5w6fw6q 5852 2 aneurysms aneurysm NNS cord-006870-f5w6fw6q 5852 3 may may MD cord-006870-f5w6fw6q 5852 4 rapidly rapidly RB cord-006870-f5w6fw6q 5852 5 expand expand VB cord-006870-f5w6fw6q 5852 6 and and CC cord-006870-f5w6fw6q 5852 7 rupture rupture VB cord-006870-f5w6fw6q 5852 8 within within IN cord-006870-f5w6fw6q 5852 9 hours hour NNS cord-006870-f5w6fw6q 5852 10 , , , cord-006870-f5w6fw6q 5852 11 as as IN cord-006870-f5w6fw6q 5852 12 shown show VBN cord-006870-f5w6fw6q 5852 13 by by IN cord-006870-f5w6fw6q 5852 14 our -PRON- PRP$ cord-006870-f5w6fw6q 5852 15 case case NN cord-006870-f5w6fw6q 5852 16 . . . cord-006870-f5w6fw6q 5853 1 Even even RB cord-006870-f5w6fw6q 5853 2 with with IN cord-006870-f5w6fw6q 5853 3 prior prior RB cord-006870-f5w6fw6q 5853 4 exonerating exonerate VBG cord-006870-f5w6fw6q 5853 5 imaging imaging NN cord-006870-f5w6fw6q 5853 6 , , , cord-006870-f5w6fw6q 5853 7 clinicians clinician NNS cord-006870-f5w6fw6q 5853 8 should should MD cord-006870-f5w6fw6q 5853 9 have have VB cord-006870-f5w6fw6q 5853 10 a a DT cord-006870-f5w6fw6q 5853 11 high high JJ cord-006870-f5w6fw6q 5853 12 suspicion suspicion NN cord-006870-f5w6fw6q 5853 13 for for IN cord-006870-f5w6fw6q 5853 14 IIA IIA NNP cord-006870-f5w6fw6q 5853 15 development development NN cord-006870-f5w6fw6q 5853 16 in in IN cord-006870-f5w6fw6q 5853 17 all all DT cord-006870-f5w6fw6q 5853 18 infective infective JJ cord-006870-f5w6fw6q 5853 19 endocarditis endocarditis NN cord-006870-f5w6fw6q 5853 20 patients patient NNS cord-006870-f5w6fw6q 5853 21 . . . cord-006870-f5w6fw6q 5854 1 The the DT cord-006870-f5w6fw6q 5854 2 corneomandibular corneomandibular JJ cord-006870-f5w6fw6q 5854 3 reflex reflex NN cord-006870-f5w6fw6q 5854 4 , , , cord-006870-f5w6fw6q 5854 5 also also RB cord-006870-f5w6fw6q 5854 6 known know VBN cord-006870-f5w6fw6q 5854 7 as as IN cord-006870-f5w6fw6q 5854 8 Wartenburg Wartenburg NNP cord-006870-f5w6fw6q 5854 9 reflex reflex NN cord-006870-f5w6fw6q 5854 10 or or CC cord-006870-f5w6fw6q 5854 11 Von Von NNP cord-006870-f5w6fw6q 5854 12 Solder Solder NNP cord-006870-f5w6fw6q 5854 13 phenomenon phenomenon NN cord-006870-f5w6fw6q 5854 14 , , , cord-006870-f5w6fw6q 5854 15 is be VBZ cord-006870-f5w6fw6q 5854 16 a a DT cord-006870-f5w6fw6q 5854 17 rare rare JJ cord-006870-f5w6fw6q 5854 18 pathological pathological JJ cord-006870-f5w6fw6q 5854 19 reflex reflex NN cord-006870-f5w6fw6q 5854 20 signifying signify VBG cord-006870-f5w6fw6q 5854 21 severe severe JJ cord-006870-f5w6fw6q 5854 22 supranuclear supranuclear NNP cord-006870-f5w6fw6q 5854 23 trigeminal trigeminal NNP cord-006870-f5w6fw6q 5854 24 injury injury NN cord-006870-f5w6fw6q 5854 25 . . . cord-006870-f5w6fw6q 5855 1 It -PRON- PRP cord-006870-f5w6fw6q 5855 2 presents present VBZ cord-006870-f5w6fw6q 5855 3 as as IN cord-006870-f5w6fw6q 5855 4 contralateral contralateral JJ cord-006870-f5w6fw6q 5855 5 jaw jaw NN cord-006870-f5w6fw6q 5855 6 deviation deviation NN cord-006870-f5w6fw6q 5855 7 to to IN cord-006870-f5w6fw6q 5855 8 corneal corneal JJ cord-006870-f5w6fw6q 5855 9 stimulation stimulation NN cord-006870-f5w6fw6q 5855 10 . . . cord-006870-f5w6fw6q 5856 1 Etiologies etiology NNS cord-006870-f5w6fw6q 5856 2 include include VBP cord-006870-f5w6fw6q 5856 3 upper upper JJ cord-006870-f5w6fw6q 5856 4 brainstem brainstem NN cord-006870-f5w6fw6q 5856 5 lesions lesion NNS cord-006870-f5w6fw6q 5856 6 , , , cord-006870-f5w6fw6q 5856 7 large large JJ cord-006870-f5w6fw6q 5856 8 hemispheric hemispheric JJ cord-006870-f5w6fw6q 5856 9 lesions lesion NNS cord-006870-f5w6fw6q 5856 10 with with IN cord-006870-f5w6fw6q 5856 11 brainstem brainstem NN cord-006870-f5w6fw6q 5856 12 compression compression NN cord-006870-f5w6fw6q 5856 13 , , , cord-006870-f5w6fw6q 5856 14 as as RB cord-006870-f5w6fw6q 5856 15 well well RB cord-006870-f5w6fw6q 5856 16 as as IN cord-006870-f5w6fw6q 5856 17 advanced advanced JJ cord-006870-f5w6fw6q 5856 18 amyotrophic amyotrophic JJ cord-006870-f5w6fw6q 5856 19 lateral lateral JJ cord-006870-f5w6fw6q 5856 20 sclerosis sclerosis NN cord-006870-f5w6fw6q 5856 21 and and CC cord-006870-f5w6fw6q 5856 22 multiple multiple JJ cord-006870-f5w6fw6q 5856 23 sclerosis sclerosis NN cord-006870-f5w6fw6q 5856 24 when when WRB cord-006870-f5w6fw6q 5856 25 corticobulbar corticobulbar NNP cord-006870-f5w6fw6q 5856 26 pathways pathway NNS cord-006870-f5w6fw6q 5856 27 are be VBP cord-006870-f5w6fw6q 5856 28 affected affect VBN cord-006870-f5w6fw6q 5856 29 . . . cord-006870-f5w6fw6q 5857 1 This this DT cord-006870-f5w6fw6q 5857 2 clinical clinical JJ cord-006870-f5w6fw6q 5857 3 finding finding NN cord-006870-f5w6fw6q 5857 4 is be VBZ cord-006870-f5w6fw6q 5857 5 useful useful JJ cord-006870-f5w6fw6q 5857 6 in in IN cord-006870-f5w6fw6q 5857 7 differentiating differentiate VBG cord-006870-f5w6fw6q 5857 8 structural structural JJ cord-006870-f5w6fw6q 5857 9 and and CC cord-006870-f5w6fw6q 5857 10 metabolic metabolic JJ cord-006870-f5w6fw6q 5857 11 causes cause NNS cord-006870-f5w6fw6q 5857 12 of of IN cord-006870-f5w6fw6q 5857 13 coma coma NN cord-006870-f5w6fw6q 5857 14 , , , cord-006870-f5w6fw6q 5857 15 as as IN cord-006870-f5w6fw6q 5857 16 this this DT cord-006870-f5w6fw6q 5857 17 examination examination NN cord-006870-f5w6fw6q 5857 18 finding finding NN cord-006870-f5w6fw6q 5857 19 would would MD cord-006870-f5w6fw6q 5857 20 not not RB cord-006870-f5w6fw6q 5857 21 be be VB cord-006870-f5w6fw6q 5857 22 present present JJ cord-006870-f5w6fw6q 5857 23 in in IN cord-006870-f5w6fw6q 5857 24 metabolic metabolic JJ cord-006870-f5w6fw6q 5857 25 phenomena phenomenon NNS cord-006870-f5w6fw6q 5857 26 . . . cord-006870-f5w6fw6q 5858 1 A a DT cord-006870-f5w6fw6q 5858 2 middle middle JJ cord-006870-f5w6fw6q 5858 3 aged aged JJ cord-006870-f5w6fw6q 5858 4 man man NN cord-006870-f5w6fw6q 5858 5 presents present VBZ cord-006870-f5w6fw6q 5858 6 with with IN cord-006870-f5w6fw6q 5858 7 a a DT cord-006870-f5w6fw6q 5858 8 hypertensive hypertensive JJ cord-006870-f5w6fw6q 5858 9 right right JJ cord-006870-f5w6fw6q 5858 10 thalamic thalamic JJ cord-006870-f5w6fw6q 5858 11 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5858 12 and and CC cord-006870-f5w6fw6q 5858 13 a a DT cord-006870-f5w6fw6q 5858 14 FOUR four CD cord-006870-f5w6fw6q 5858 15 score score NN cord-006870-f5w6fw6q 5858 16 of of IN cord-006870-f5w6fw6q 5858 17 E0M0B0R1 e0m0b0r1 NN cord-006870-f5w6fw6q 5858 18 . . . cord-006870-f5w6fw6q 5859 1 The the DT cord-006870-f5w6fw6q 5859 2 patient patient NN cord-006870-f5w6fw6q 5859 3 's 's POS cord-006870-f5w6fw6q 5859 4 cornea cornea NN cord-006870-f5w6fw6q 5859 5 was be VBD cord-006870-f5w6fw6q 5859 6 stimulated stimulate VBN cord-006870-f5w6fw6q 5859 7 with with IN cord-006870-f5w6fw6q 5859 8 a a DT cord-006870-f5w6fw6q 5859 9 cotton cotton NN cord-006870-f5w6fw6q 5859 10 swab swab NN cord-006870-f5w6fw6q 5859 11 . . . cord-006870-f5w6fw6q 5860 1 The the DT cord-006870-f5w6fw6q 5860 2 cornea cornea NN cord-006870-f5w6fw6q 5860 3 was be VBD cord-006870-f5w6fw6q 5860 4 tested test VBN cord-006870-f5w6fw6q 5860 5 bilaterally bilaterally RB cord-006870-f5w6fw6q 5860 6 to to TO cord-006870-f5w6fw6q 5860 7 determine determine VB cord-006870-f5w6fw6q 5860 8 any any DT cord-006870-f5w6fw6q 5860 9 lateralizing lateralizing NN cord-006870-f5w6fw6q 5860 10 features feature NNS cord-006870-f5w6fw6q 5860 11 . . . cord-006870-f5w6fw6q 5861 1 Recording record VBG cord-006870-f5w6fw6q 5861 2 on on IN cord-006870-f5w6fw6q 5861 3 video video NN cord-006870-f5w6fw6q 5861 4 was be VBD cord-006870-f5w6fw6q 5861 5 performed perform VBN cord-006870-f5w6fw6q 5861 6 with with IN cord-006870-f5w6fw6q 5861 7 patient patient NN cord-006870-f5w6fw6q 5861 8 's 's POS cord-006870-f5w6fw6q 5861 9 family family NN cord-006870-f5w6fw6q 5861 10 written write VBN cord-006870-f5w6fw6q 5861 11 consent consent NN cord-006870-f5w6fw6q 5861 12 as as IN cord-006870-f5w6fw6q 5861 13 patient patient NN cord-006870-f5w6fw6q 5861 14 was be VBD cord-006870-f5w6fw6q 5861 15 comatose comatose JJ cord-006870-f5w6fw6q 5861 16 . . . cord-006870-f5w6fw6q 5862 1 Upon upon IN cord-006870-f5w6fw6q 5862 2 stimulation stimulation NN cord-006870-f5w6fw6q 5862 3 of of IN cord-006870-f5w6fw6q 5862 4 the the DT cord-006870-f5w6fw6q 5862 5 patient patient NN cord-006870-f5w6fw6q 5862 6 's 's POS cord-006870-f5w6fw6q 5862 7 cornea cornea NN cord-006870-f5w6fw6q 5862 8 a a DT cord-006870-f5w6fw6q 5862 9 contralateral contralateral JJ cord-006870-f5w6fw6q 5862 10 jaw jaw NN cord-006870-f5w6fw6q 5862 11 jerk jerk NN cord-006870-f5w6fw6q 5862 12 was be VBD cord-006870-f5w6fw6q 5862 13 appreciated appreciate VBN cord-006870-f5w6fw6q 5862 14 . . . cord-006870-f5w6fw6q 5863 1 This this DT cord-006870-f5w6fw6q 5863 2 was be VBD cord-006870-f5w6fw6q 5863 3 replicated replicate VBN cord-006870-f5w6fw6q 5863 4 contralaterally contralaterally RB cord-006870-f5w6fw6q 5863 5 . . . cord-006870-f5w6fw6q 5864 1 This this DT cord-006870-f5w6fw6q 5864 2 case case NN cord-006870-f5w6fw6q 5864 3 describes describe VBZ cord-006870-f5w6fw6q 5864 4 a a DT cord-006870-f5w6fw6q 5864 5 common common JJ cord-006870-f5w6fw6q 5864 6 patient patient NN cord-006870-f5w6fw6q 5864 7 with with IN cord-006870-f5w6fw6q 5864 8 a a DT cord-006870-f5w6fw6q 5864 9 rare rare JJ cord-006870-f5w6fw6q 5864 10 physical physical JJ cord-006870-f5w6fw6q 5864 11 examination examination NN cord-006870-f5w6fw6q 5864 12 finding finding NN cord-006870-f5w6fw6q 5864 13 . . . cord-006870-f5w6fw6q 5865 1 There there EX cord-006870-f5w6fw6q 5865 2 is be VBZ cord-006870-f5w6fw6q 5865 3 utility utility NN cord-006870-f5w6fw6q 5865 4 in in IN cord-006870-f5w6fw6q 5865 5 recognizing recognize VBG cord-006870-f5w6fw6q 5865 6 this this DT cord-006870-f5w6fw6q 5865 7 finding finding NN cord-006870-f5w6fw6q 5865 8 as as IN cord-006870-f5w6fw6q 5865 9 it -PRON- PRP cord-006870-f5w6fw6q 5865 10 will will MD cord-006870-f5w6fw6q 5865 11 aid aid VB cord-006870-f5w6fw6q 5865 12 in in IN cord-006870-f5w6fw6q 5865 13 determination determination NN cord-006870-f5w6fw6q 5865 14 of of IN cord-006870-f5w6fw6q 5865 15 the the DT cord-006870-f5w6fw6q 5865 16 underlying underlying JJ cord-006870-f5w6fw6q 5865 17 cause cause NN cord-006870-f5w6fw6q 5865 18 of of IN cord-006870-f5w6fw6q 5865 19 a a DT cord-006870-f5w6fw6q 5865 20 comatose comatose JJ cord-006870-f5w6fw6q 5865 21 state state NN cord-006870-f5w6fw6q 5865 22 . . . cord-006870-f5w6fw6q 5866 1 The the DT cord-006870-f5w6fw6q 5866 2 corneomandibular corneomandibular JJ cord-006870-f5w6fw6q 5866 3 reflex reflex NN cord-006870-f5w6fw6q 5866 4 present present JJ cord-006870-f5w6fw6q 5866 5 at at IN cord-006870-f5w6fw6q 5866 6 presentation presentation NN cord-006870-f5w6fw6q 5866 7 rules rule VBZ cord-006870-f5w6fw6q 5866 8 out out RP cord-006870-f5w6fw6q 5866 9 a a DT cord-006870-f5w6fw6q 5866 10 metabolic metabolic JJ cord-006870-f5w6fw6q 5866 11 cause cause NN cord-006870-f5w6fw6q 5866 12 . . . cord-006870-f5w6fw6q 5867 1 A a DT cord-006870-f5w6fw6q 5867 2 structural structural JJ cord-006870-f5w6fw6q 5867 3 cause cause NN cord-006870-f5w6fw6q 5867 4 was be VBD cord-006870-f5w6fw6q 5867 5 validated validate VBN cord-006870-f5w6fw6q 5867 6 by by IN cord-006870-f5w6fw6q 5867 7 imaging image VBG cord-006870-f5w6fw6q 5867 8 studies study NNS cord-006870-f5w6fw6q 5867 9 ( ( -LRB- cord-006870-f5w6fw6q 5867 10 shown show VBN cord-006870-f5w6fw6q 5867 11 ) ) -RRB- cord-006870-f5w6fw6q 5867 12 . . . cord-006870-f5w6fw6q 5868 1 The the DT cord-006870-f5w6fw6q 5868 2 reflex reflex NN cord-006870-f5w6fw6q 5868 3 arc arc NNP cord-006870-f5w6fw6q 5868 4 was be VBD cord-006870-f5w6fw6q 5868 5 researched research VBN cord-006870-f5w6fw6q 5868 6 and and CC cord-006870-f5w6fw6q 5868 7 has have VBZ cord-006870-f5w6fw6q 5868 8 been be VBN cord-006870-f5w6fw6q 5868 9 independently independently RB cord-006870-f5w6fw6q 5868 10 artistically artistically RB cord-006870-f5w6fw6q 5868 11 rendered render VBN cord-006870-f5w6fw6q 5868 12 ( ( -LRB- cord-006870-f5w6fw6q 5868 13 shown show VBN cord-006870-f5w6fw6q 5868 14 ) ) -RRB- cord-006870-f5w6fw6q 5868 15 , , , cord-006870-f5w6fw6q 5868 16 which which WDT cord-006870-f5w6fw6q 5868 17 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 5868 18 the the DT cord-006870-f5w6fw6q 5868 19 pathway pathway NN cord-006870-f5w6fw6q 5868 20 beginning begin VBG cord-006870-f5w6fw6q 5868 21 with with IN cord-006870-f5w6fw6q 5868 22 the the DT cord-006870-f5w6fw6q 5868 23 afferent afferent JJ cord-006870-f5w6fw6q 5868 24 limb limb NN cord-006870-f5w6fw6q 5868 25 of of IN cord-006870-f5w6fw6q 5868 26 the the DT cord-006870-f5w6fw6q 5868 27 corneal corneal JJ cord-006870-f5w6fw6q 5868 28 stimulus stimulus NN cord-006870-f5w6fw6q 5868 29 ( ( -LRB- cord-006870-f5w6fw6q 5868 30 V1 v1 NN cord-006870-f5w6fw6q 5868 31 ) ) -RRB- cord-006870-f5w6fw6q 5868 32 which which WDT cord-006870-f5w6fw6q 5868 33 travels travel VBZ cord-006870-f5w6fw6q 5868 34 to to IN cord-006870-f5w6fw6q 5868 35 the the DT cord-006870-f5w6fw6q 5868 36 main main JJ cord-006870-f5w6fw6q 5868 37 trigeminal trigeminal JJ cord-006870-f5w6fw6q 5868 38 sensory sensory JJ cord-006870-f5w6fw6q 5868 39 nucleus nucleus NN cord-006870-f5w6fw6q 5868 40 via via IN cord-006870-f5w6fw6q 5868 41 the the DT cord-006870-f5w6fw6q 5868 42 trigeminal trigeminal JJ cord-006870-f5w6fw6q 5868 43 ganglion ganglion NN cord-006870-f5w6fw6q 5868 44 . . . cord-006870-f5w6fw6q 5869 1 Severe severe JJ cord-006870-f5w6fw6q 5869 2 supranuclear supranuclear NN cord-006870-f5w6fw6q 5869 3 trigeminal trigeminal JJ cord-006870-f5w6fw6q 5869 4 lesions lesion NNS cord-006870-f5w6fw6q 5869 5 will will MD cord-006870-f5w6fw6q 5869 6 inhibit inhibit VB cord-006870-f5w6fw6q 5869 7 inhibitory inhibitory JJ cord-006870-f5w6fw6q 5869 8 interneurons interneuron NNS cord-006870-f5w6fw6q 5869 9 within within IN cord-006870-f5w6fw6q 5869 10 the the DT cord-006870-f5w6fw6q 5869 11 mesencephalic mesencephalic NNP cord-006870-f5w6fw6q 5869 12 nucleus nucleus NN cord-006870-f5w6fw6q 5869 13 , , , cord-006870-f5w6fw6q 5869 14 leading lead VBG cord-006870-f5w6fw6q 5869 15 to to IN cord-006870-f5w6fw6q 5869 16 activation activation NN cord-006870-f5w6fw6q 5869 17 of of IN cord-006870-f5w6fw6q 5869 18 the the DT cord-006870-f5w6fw6q 5869 19 motor motor NN cord-006870-f5w6fw6q 5869 20 nucleus nucleus NN cord-006870-f5w6fw6q 5869 21 of of IN cord-006870-f5w6fw6q 5869 22 the the DT cord-006870-f5w6fw6q 5869 23 trigeminal trigeminal JJ cord-006870-f5w6fw6q 5869 24 nerve nerve NN cord-006870-f5w6fw6q 5869 25 . . . cord-006870-f5w6fw6q 5870 1 This this DT cord-006870-f5w6fw6q 5870 2 causes cause VBZ cord-006870-f5w6fw6q 5870 3 activation activation NN cord-006870-f5w6fw6q 5870 4 of of IN cord-006870-f5w6fw6q 5870 5 the the DT cord-006870-f5w6fw6q 5870 6 ipsilateral ipsilateral JJ cord-006870-f5w6fw6q 5870 7 external external JJ cord-006870-f5w6fw6q 5870 8 pterygoid pterygoid NN cord-006870-f5w6fw6q 5870 9 muscle muscle NN cord-006870-f5w6fw6q 5870 10 which which WDT cord-006870-f5w6fw6q 5870 11 produces produce VBZ cord-006870-f5w6fw6q 5870 12 a a DT cord-006870-f5w6fw6q 5870 13 contralateral contralateral JJ cord-006870-f5w6fw6q 5870 14 jaw jaw NN cord-006870-f5w6fw6q 5870 15 jerk jerk NN cord-006870-f5w6fw6q 5870 16 . . . cord-006870-f5w6fw6q 5871 1 Overall overall RB cord-006870-f5w6fw6q 5871 2 this this DT cord-006870-f5w6fw6q 5871 3 patient patient NN cord-006870-f5w6fw6q 5871 4 fared fare VBD cord-006870-f5w6fw6q 5871 5 poorly poorly RB cord-006870-f5w6fw6q 5871 6 and and CC cord-006870-f5w6fw6q 5871 7 expired expire VBD cord-006870-f5w6fw6q 5871 8 several several JJ cord-006870-f5w6fw6q 5871 9 days day NNS cord-006870-f5w6fw6q 5871 10 after after IN cord-006870-f5w6fw6q 5871 11 admission admission NN cord-006870-f5w6fw6q 5871 12 . . . cord-006870-f5w6fw6q 5872 1 Pneumocephalus Pneumocephalus NNP cord-006870-f5w6fw6q 5872 2 is be VBZ cord-006870-f5w6fw6q 5872 3 when when WRB cord-006870-f5w6fw6q 5872 4 air air NN cord-006870-f5w6fw6q 5872 5 enters enter VBZ cord-006870-f5w6fw6q 5872 6 and and CC cord-006870-f5w6fw6q 5872 7 is be VBZ cord-006870-f5w6fw6q 5872 8 contained contain VBN cord-006870-f5w6fw6q 5872 9 inside inside IN cord-006870-f5w6fw6q 5872 10 the the DT cord-006870-f5w6fw6q 5872 11 intracranial intracranial JJ cord-006870-f5w6fw6q 5872 12 compartment compartment NN cord-006870-f5w6fw6q 5872 13 . . . cord-006870-f5w6fw6q 5873 1 When when WRB cord-006870-f5w6fw6q 5873 2 intracranial intracranial JJ cord-006870-f5w6fw6q 5873 3 pressure pressure NN cord-006870-f5w6fw6q 5873 4 increases increase NNS cord-006870-f5w6fw6q 5873 5 causing cause VBG cord-006870-f5w6fw6q 5873 6 neurological neurological JJ cord-006870-f5w6fw6q 5873 7 decline decline NN cord-006870-f5w6fw6q 5873 8 , , , cord-006870-f5w6fw6q 5873 9 patients patient NNS cord-006870-f5w6fw6q 5873 10 can can MD cord-006870-f5w6fw6q 5873 11 experience experience VB cord-006870-f5w6fw6q 5873 12 nausea nausea NN cord-006870-f5w6fw6q 5873 13 , , , cord-006870-f5w6fw6q 5873 14 vomiting vomiting NN cord-006870-f5w6fw6q 5873 15 , , , cord-006870-f5w6fw6q 5873 16 seizures seizure NNS cord-006870-f5w6fw6q 5873 17 , , , cord-006870-f5w6fw6q 5873 18 dizziness dizziness NN cord-006870-f5w6fw6q 5873 19 , , , cord-006870-f5w6fw6q 5873 20 and and CC cord-006870-f5w6fw6q 5873 21 altered alter VBN cord-006870-f5w6fw6q 5873 22 mental mental JJ cord-006870-f5w6fw6q 5873 23 status status NN cord-006870-f5w6fw6q 5873 24 . . . cord-006870-f5w6fw6q 5874 1 Here here RB cord-006870-f5w6fw6q 5874 2 we -PRON- PRP cord-006870-f5w6fw6q 5874 3 present present VBP cord-006870-f5w6fw6q 5874 4 three three CD cord-006870-f5w6fw6q 5874 5 cases case NNS cord-006870-f5w6fw6q 5874 6 of of IN cord-006870-f5w6fw6q 5874 7 postoperative postoperative JJ cord-006870-f5w6fw6q 5874 8 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5874 9 which which WDT cord-006870-f5w6fw6q 5874 10 resolved resolve VBD cord-006870-f5w6fw6q 5874 11 quickly quickly RB cord-006870-f5w6fw6q 5874 12 with with IN cord-006870-f5w6fw6q 5874 13 humidified humidify VBN cord-006870-f5w6fw6q 5874 14 oxygen oxygen NN cord-006870-f5w6fw6q 5874 15 delivery delivery NN cord-006870-f5w6fw6q 5874 16 via via IN cord-006870-f5w6fw6q 5874 17 high high JJ cord-006870-f5w6fw6q 5874 18 - - HYPH cord-006870-f5w6fw6q 5874 19 flow flow NN cord-006870-f5w6fw6q 5874 20 nasal nasal NN cord-006870-f5w6fw6q 5874 21 cannula cannula NN cord-006870-f5w6fw6q 5874 22 . . . cord-006870-f5w6fw6q 5875 1 We -PRON- PRP cord-006870-f5w6fw6q 5875 2 follow follow VBP cord-006870-f5w6fw6q 5875 3 the the DT cord-006870-f5w6fw6q 5875 4 cases case NNS cord-006870-f5w6fw6q 5875 5 with with IN cord-006870-f5w6fw6q 5875 6 a a DT cord-006870-f5w6fw6q 5875 7 review review NN cord-006870-f5w6fw6q 5875 8 of of IN cord-006870-f5w6fw6q 5875 9 the the DT cord-006870-f5w6fw6q 5875 10 mechanisms mechanism NNS cord-006870-f5w6fw6q 5875 11 and and CC cord-006870-f5w6fw6q 5875 12 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 5875 13 of of IN cord-006870-f5w6fw6q 5875 14 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5875 15 and and CC cord-006870-f5w6fw6q 5875 16 its -PRON- PRP$ cord-006870-f5w6fw6q 5875 17 treatment treatment NN cord-006870-f5w6fw6q 5875 18 , , , cord-006870-f5w6fw6q 5875 19 as as RB cord-006870-f5w6fw6q 5875 20 well well RB cord-006870-f5w6fw6q 5875 21 as as IN cord-006870-f5w6fw6q 5875 22 future future JJ cord-006870-f5w6fw6q 5875 23 directions direction NNS cord-006870-f5w6fw6q 5875 24 in in IN cord-006870-f5w6fw6q 5875 25 management management NN cord-006870-f5w6fw6q 5875 26 . . . cord-006870-f5w6fw6q 5876 1 Case case NN cord-006870-f5w6fw6q 5876 2 series series NN cord-006870-f5w6fw6q 5876 3 of of IN cord-006870-f5w6fw6q 5876 4 3 3 CD cord-006870-f5w6fw6q 5876 5 patients patient NNS cord-006870-f5w6fw6q 5876 6 with with IN cord-006870-f5w6fw6q 5876 7 post post JJ cord-006870-f5w6fw6q 5876 8 - - JJ cord-006870-f5w6fw6q 5876 9 operative operative JJ cord-006870-f5w6fw6q 5876 10 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5876 11 who who WP cord-006870-f5w6fw6q 5876 12 were be VBD cord-006870-f5w6fw6q 5876 13 treated treat VBN cord-006870-f5w6fw6q 5876 14 with with IN cord-006870-f5w6fw6q 5876 15 high high JJ cord-006870-f5w6fw6q 5876 16 - - HYPH cord-006870-f5w6fw6q 5876 17 flow flow NN cord-006870-f5w6fw6q 5876 18 nasal nasal NN cord-006870-f5w6fw6q 5876 19 cannula cannula NN cord-006870-f5w6fw6q 5876 20 . . . cord-006870-f5w6fw6q 5877 1 Case case NN cord-006870-f5w6fw6q 5877 2 1 1 CD cord-006870-f5w6fw6q 5877 3 describes describe VBZ cord-006870-f5w6fw6q 5877 4 a a DT cord-006870-f5w6fw6q 5877 5 78-year 78-year JJ cord-006870-f5w6fw6q 5877 6 - - HYPH cord-006870-f5w6fw6q 5877 7 old old JJ cord-006870-f5w6fw6q 5877 8 woman woman NN cord-006870-f5w6fw6q 5877 9 who who WP cord-006870-f5w6fw6q 5877 10 underwent undergo VBD cord-006870-f5w6fw6q 5877 11 hemicraniotomy hemicraniotomy NN cord-006870-f5w6fw6q 5877 12 for for IN cord-006870-f5w6fw6q 5877 13 removal removal NN cord-006870-f5w6fw6q 5877 14 of of IN cord-006870-f5w6fw6q 5877 15 meningiomas meningiomas NNP cord-006870-f5w6fw6q 5877 16 , , , cord-006870-f5w6fw6q 5877 17 with with IN cord-006870-f5w6fw6q 5877 18 focal focal JJ cord-006870-f5w6fw6q 5877 19 postoperative postoperative JJ cord-006870-f5w6fw6q 5877 20 neurological neurological JJ cord-006870-f5w6fw6q 5877 21 signs sign NNS cord-006870-f5w6fw6q 5877 22 and and CC cord-006870-f5w6fw6q 5877 23 8 8 CD cord-006870-f5w6fw6q 5877 24 mm mm CD cord-006870-f5w6fw6q 5877 25 of of IN cord-006870-f5w6fw6q 5877 26 midline midline JJ cord-006870-f5w6fw6q 5877 27 shift shift NN cord-006870-f5w6fw6q 5877 28 on on IN cord-006870-f5w6fw6q 5877 29 head head NN cord-006870-f5w6fw6q 5877 30 CT CT NNP cord-006870-f5w6fw6q 5877 31 due due JJ cord-006870-f5w6fw6q 5877 32 to to IN cord-006870-f5w6fw6q 5877 33 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5877 34 . . . cord-006870-f5w6fw6q 5878 1 Case case NN cord-006870-f5w6fw6q 5878 2 2 2 CD cord-006870-f5w6fw6q 5878 3 describes describe VBZ cord-006870-f5w6fw6q 5878 4 a a DT cord-006870-f5w6fw6q 5878 5 57-year 57-year JJ cord-006870-f5w6fw6q 5878 6 - - HYPH cord-006870-f5w6fw6q 5878 7 old old JJ cord-006870-f5w6fw6q 5878 8 woman woman NN cord-006870-f5w6fw6q 5878 9 who who WP cord-006870-f5w6fw6q 5878 10 underwent undergo VBD cord-006870-f5w6fw6q 5878 11 right right JJ cord-006870-f5w6fw6q 5878 12 anterior anterior FW cord-006870-f5w6fw6q 5878 13 temporal temporal JJ cord-006870-f5w6fw6q 5878 14 lobectomy lobectomy NN cord-006870-f5w6fw6q 5878 15 for for IN cord-006870-f5w6fw6q 5878 16 seizures seizure NNS cord-006870-f5w6fw6q 5878 17 , , , cord-006870-f5w6fw6q 5878 18 who who WP cord-006870-f5w6fw6q 5878 19 developed develop VBD cord-006870-f5w6fw6q 5878 20 postoperative postoperative JJ cord-006870-f5w6fw6q 5878 21 focal focal JJ cord-006870-f5w6fw6q 5878 22 prefrontal prefrontal JJ cord-006870-f5w6fw6q 5878 23 lobe lobe NN cord-006870-f5w6fw6q 5878 24 signs sign NNS cord-006870-f5w6fw6q 5878 25 and and CC cord-006870-f5w6fw6q 5878 26 Mount Mount NNP cord-006870-f5w6fw6q 5878 27 Fuji Fuji NNP cord-006870-f5w6fw6q 5878 28 sign sign NN cord-006870-f5w6fw6q 5878 29 on on IN cord-006870-f5w6fw6q 5878 30 head head NN cord-006870-f5w6fw6q 5878 31 CT CT NNP cord-006870-f5w6fw6q 5878 32 . . . cord-006870-f5w6fw6q 5879 1 Case case NN cord-006870-f5w6fw6q 5879 2 3 3 CD cord-006870-f5w6fw6q 5879 3 describes describe VBZ cord-006870-f5w6fw6q 5879 4 a a DT cord-006870-f5w6fw6q 5879 5 58-year 58-year JJ cord-006870-f5w6fw6q 5879 6 - - HYPH cord-006870-f5w6fw6q 5879 7 old old JJ cord-006870-f5w6fw6q 5879 8 man man NN cord-006870-f5w6fw6q 5879 9 with with IN cord-006870-f5w6fw6q 5879 10 bilateral bilateral JJ cord-006870-f5w6fw6q 5879 11 subdural subdural JJ cord-006870-f5w6fw6q 5879 12 hematomas hematoma NNS cord-006870-f5w6fw6q 5879 13 , , , cord-006870-f5w6fw6q 5879 14 status status NN cord-006870-f5w6fw6q 5879 15 post post FW cord-006870-f5w6fw6q 5879 16 bilateral bilateral JJ cord-006870-f5w6fw6q 5879 17 burr burr NNP cord-006870-f5w6fw6q 5879 18 hole hole NN cord-006870-f5w6fw6q 5879 19 evacuation evacuation NN cord-006870-f5w6fw6q 5879 20 . . . cord-006870-f5w6fw6q 5880 1 He -PRON- PRP cord-006870-f5w6fw6q 5880 2 was be VBD cord-006870-f5w6fw6q 5880 3 excessively excessively RB cord-006870-f5w6fw6q 5880 4 somnalent somnalent VBN cord-006870-f5w6fw6q 5880 5 postoperatively postoperatively RB cord-006870-f5w6fw6q 5880 6 with with IN cord-006870-f5w6fw6q 5880 7 bilateral bilateral JJ cord-006870-f5w6fw6q 5880 8 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5880 9 . . . cord-006870-f5w6fw6q 5881 1 With with IN cord-006870-f5w6fw6q 5881 2 high high JJ cord-006870-f5w6fw6q 5881 3 - - HYPH cord-006870-f5w6fw6q 5881 4 flow flow NN cord-006870-f5w6fw6q 5881 5 nasal nasal NN cord-006870-f5w6fw6q 5881 6 cannula cannula NN cord-006870-f5w6fw6q 5881 7 , , , cord-006870-f5w6fw6q 5881 8 they -PRON- PRP cord-006870-f5w6fw6q 5881 9 all all DT cord-006870-f5w6fw6q 5881 10 returned return VBD cord-006870-f5w6fw6q 5881 11 to to IN cord-006870-f5w6fw6q 5881 12 clinical clinical JJ cord-006870-f5w6fw6q 5881 13 , , , cord-006870-f5w6fw6q 5881 14 and and CC cord-006870-f5w6fw6q 5881 15 near near IN cord-006870-f5w6fw6q 5881 16 radiographic radiographic JJ cord-006870-f5w6fw6q 5881 17 baseline baseline NN cord-006870-f5w6fw6q 5881 18 within within IN cord-006870-f5w6fw6q 5881 19 8 8 CD cord-006870-f5w6fw6q 5881 20 , , , cord-006870-f5w6fw6q 5881 21 12 12 CD cord-006870-f5w6fw6q 5881 22 , , , cord-006870-f5w6fw6q 5881 23 and and CC cord-006870-f5w6fw6q 5881 24 20 20 CD cord-006870-f5w6fw6q 5881 25 hours hour NNS cord-006870-f5w6fw6q 5881 26 , , , cord-006870-f5w6fw6q 5881 27 respectively respectively RB cord-006870-f5w6fw6q 5881 28 . . . cord-006870-f5w6fw6q 5882 1 Recognizing recognize VBG cord-006870-f5w6fw6q 5882 2 the the DT cord-006870-f5w6fw6q 5882 3 limitations limitation NNS cord-006870-f5w6fw6q 5882 4 of of IN cord-006870-f5w6fw6q 5882 5 a a DT cord-006870-f5w6fw6q 5882 6 small small JJ cord-006870-f5w6fw6q 5882 7 case case NN cord-006870-f5w6fw6q 5882 8 series series NN cord-006870-f5w6fw6q 5882 9 , , , cord-006870-f5w6fw6q 5882 10 we -PRON- PRP cord-006870-f5w6fw6q 5882 11 believe believe VBP cord-006870-f5w6fw6q 5882 12 these these DT cord-006870-f5w6fw6q 5882 13 cases case NNS cord-006870-f5w6fw6q 5882 14 support support VBP cord-006870-f5w6fw6q 5882 15 use use NN cord-006870-f5w6fw6q 5882 16 of of IN cord-006870-f5w6fw6q 5882 17 high high JJ cord-006870-f5w6fw6q 5882 18 - - HYPH cord-006870-f5w6fw6q 5882 19 flow flow NN cord-006870-f5w6fw6q 5882 20 nasal nasal NN cord-006870-f5w6fw6q 5882 21 cannula cannula NN cord-006870-f5w6fw6q 5882 22 when when WRB cord-006870-f5w6fw6q 5882 23 treating treat VBG cord-006870-f5w6fw6q 5882 24 patients patient NNS cord-006870-f5w6fw6q 5882 25 with with IN cord-006870-f5w6fw6q 5882 26 symptomatic symptomatic JJ cord-006870-f5w6fw6q 5882 27 pneumocephalus pneumocephalus NN cord-006870-f5w6fw6q 5882 28 . . . cord-006870-f5w6fw6q 5883 1 Thsee Thsee NNP cord-006870-f5w6fw6q 5883 2 patients patient NNS cord-006870-f5w6fw6q 5883 3 showed show VBD cord-006870-f5w6fw6q 5883 4 more more RBR cord-006870-f5w6fw6q 5883 5 rapid rapid JJ cord-006870-f5w6fw6q 5883 6 clinical clinical JJ cord-006870-f5w6fw6q 5883 7 and and CC cord-006870-f5w6fw6q 5883 8 radiographic radiographic JJ cord-006870-f5w6fw6q 5883 9 improvement improvement NN cord-006870-f5w6fw6q 5883 10 after after IN cord-006870-f5w6fw6q 5883 11 implementation implementation NN cord-006870-f5w6fw6q 5883 12 of of IN cord-006870-f5w6fw6q 5883 13 HFNC HFNC NNP cord-006870-f5w6fw6q 5883 14 oxygen oxygen NN cord-006870-f5w6fw6q 5883 15 therapy therapy NN cord-006870-f5w6fw6q 5883 16 than than IN cord-006870-f5w6fw6q 5883 17 previously previously RB cord-006870-f5w6fw6q 5883 18 described describe VBN cord-006870-f5w6fw6q 5883 19 using use VBG cord-006870-f5w6fw6q 5883 20 other other JJ cord-006870-f5w6fw6q 5883 21 methods method NNS cord-006870-f5w6fw6q 5883 22 . . . cord-006870-f5w6fw6q 5884 1 High high JJ cord-006870-f5w6fw6q 5884 2 - - HYPH cord-006870-f5w6fw6q 5884 3 flow flow NN cord-006870-f5w6fw6q 5884 4 nasal nasal NN cord-006870-f5w6fw6q 5884 5 cannula cannula NN cord-006870-f5w6fw6q 5884 6 may may MD cord-006870-f5w6fw6q 5884 7 help help VB cord-006870-f5w6fw6q 5884 8 washout washout VB cord-006870-f5w6fw6q 5884 9 nitrogen nitrogen NN cord-006870-f5w6fw6q 5884 10 from from IN cord-006870-f5w6fw6q 5884 11 the the DT cord-006870-f5w6fw6q 5884 12 lungs lung NNS cord-006870-f5w6fw6q 5884 13 , , , cord-006870-f5w6fw6q 5884 14 allowing allow VBG cord-006870-f5w6fw6q 5884 15 a a DT cord-006870-f5w6fw6q 5884 16 downward downward JJ cord-006870-f5w6fw6q 5884 17 gradient gradient NN cord-006870-f5w6fw6q 5884 18 from from IN cord-006870-f5w6fw6q 5884 19 the the DT cord-006870-f5w6fw6q 5884 20 nitrogen nitrogen NN cord-006870-f5w6fw6q 5884 21 in in IN cord-006870-f5w6fw6q 5884 22 the the DT cord-006870-f5w6fw6q 5884 23 intracranial intracranial JJ cord-006870-f5w6fw6q 5884 24 air air NN cord-006870-f5w6fw6q 5884 25 bubble bubble NN cord-006870-f5w6fw6q 5884 26 out out IN cord-006870-f5w6fw6q 5884 27 the the DT cord-006870-f5w6fw6q 5884 28 lungs lung NNS cord-006870-f5w6fw6q 5884 29 . . . cord-006870-f5w6fw6q 5885 1 In in IN cord-006870-f5w6fw6q 5885 2 addition addition NN cord-006870-f5w6fw6q 5885 3 , , , cord-006870-f5w6fw6q 5885 4 high high JJ cord-006870-f5w6fw6q 5885 5 - - HYPH cord-006870-f5w6fw6q 5885 6 flow flow NN cord-006870-f5w6fw6q 5885 7 nasal nasal NN cord-006870-f5w6fw6q 5885 8 cannula cannula NN cord-006870-f5w6fw6q 5885 9 is be VBZ cord-006870-f5w6fw6q 5885 10 more more RBR cord-006870-f5w6fw6q 5885 11 comfortable comfortable JJ cord-006870-f5w6fw6q 5885 12 for for IN cord-006870-f5w6fw6q 5885 13 the the DT cord-006870-f5w6fw6q 5885 14 patient patient NN cord-006870-f5w6fw6q 5885 15 , , , cord-006870-f5w6fw6q 5885 16 allowing allow VBG cord-006870-f5w6fw6q 5885 17 for for IN cord-006870-f5w6fw6q 5885 18 more more RBR cord-006870-f5w6fw6q 5885 19 consistent consistent JJ cord-006870-f5w6fw6q 5885 20 treatment treatment NN cord-006870-f5w6fw6q 5885 21 . . . cord-006870-f5w6fw6q 5886 1 Randomized randomized JJ cord-006870-f5w6fw6q 5886 2 studies study NNS cord-006870-f5w6fw6q 5886 3 are be VBP cord-006870-f5w6fw6q 5886 4 needed need VBN cord-006870-f5w6fw6q 5886 5 to to TO cord-006870-f5w6fw6q 5886 6 confirm confirm VB cord-006870-f5w6fw6q 5886 7 our -PRON- PRP$ cord-006870-f5w6fw6q 5886 8 findings finding NNS cord-006870-f5w6fw6q 5886 9 . . . cord-006870-f5w6fw6q 5887 1 The the DT cord-006870-f5w6fw6q 5887 2 neurotoxin neurotoxin NN cord-006870-f5w6fw6q 5887 3 produced produce VBN cord-006870-f5w6fw6q 5887 4 by by IN cord-006870-f5w6fw6q 5887 5 Clostridium clostridium NN cord-006870-f5w6fw6q 5887 6 botulinum botulinum NN cord-006870-f5w6fw6q 5887 7 is be VBZ cord-006870-f5w6fw6q 5887 8 the the DT cord-006870-f5w6fw6q 5887 9 most most RBS cord-006870-f5w6fw6q 5887 10 lethal lethal JJ cord-006870-f5w6fw6q 5887 11 toxin toxin NN cord-006870-f5w6fw6q 5887 12 known know VBN cord-006870-f5w6fw6q 5887 13 by by IN cord-006870-f5w6fw6q 5887 14 weight weight NN cord-006870-f5w6fw6q 5887 15 . . . cord-006870-f5w6fw6q 5888 1 Early early JJ cord-006870-f5w6fw6q 5888 2 recognition recognition NN cord-006870-f5w6fw6q 5888 3 and and CC cord-006870-f5w6fw6q 5888 4 treatment treatment NN cord-006870-f5w6fw6q 5888 5 of of IN cord-006870-f5w6fw6q 5888 6 Botulism botulism NN cord-006870-f5w6fw6q 5888 7 are be VBP cord-006870-f5w6fw6q 5888 8 crucial crucial JJ cord-006870-f5w6fw6q 5888 9 for for IN cord-006870-f5w6fw6q 5888 10 full full JJ cord-006870-f5w6fw6q 5888 11 recovery recovery NN cord-006870-f5w6fw6q 5888 12 . . . cord-006870-f5w6fw6q 5889 1 We -PRON- PRP cord-006870-f5w6fw6q 5889 2 present present VBP cord-006870-f5w6fw6q 5889 3 a a DT cord-006870-f5w6fw6q 5889 4 case case NN cord-006870-f5w6fw6q 5889 5 of of IN cord-006870-f5w6fw6q 5889 6 progressive progressive JJ cord-006870-f5w6fw6q 5889 7 paralysis paralysis NN cord-006870-f5w6fw6q 5889 8 secondary secondary JJ cord-006870-f5w6fw6q 5889 9 to to IN cord-006870-f5w6fw6q 5889 10 botulism botulism NN cord-006870-f5w6fw6q 5889 11 toxemia toxemia NN cord-006870-f5w6fw6q 5889 12 following follow VBG cord-006870-f5w6fw6q 5889 13 a a DT cord-006870-f5w6fw6q 5889 14 gunshot gunshot NN cord-006870-f5w6fw6q 5889 15 wound wound NN cord-006870-f5w6fw6q 5889 16 ( ( -LRB- cord-006870-f5w6fw6q 5889 17 GSW GSW NNP cord-006870-f5w6fw6q 5889 18 ) ) -RRB- cord-006870-f5w6fw6q 5889 19 . . . cord-006870-f5w6fw6q 5890 1 A a DT cord-006870-f5w6fw6q 5890 2 27-year 27-year JJ cord-006870-f5w6fw6q 5890 3 - - HYPH cord-006870-f5w6fw6q 5890 4 old old JJ cord-006870-f5w6fw6q 5890 5 man man NN cord-006870-f5w6fw6q 5890 6 suffered suffer VBD cord-006870-f5w6fw6q 5890 7 a a DT cord-006870-f5w6fw6q 5890 8 GSW GSW NNP cord-006870-f5w6fw6q 5890 9 to to IN cord-006870-f5w6fw6q 5890 10 the the DT cord-006870-f5w6fw6q 5890 11 right right JJ cord-006870-f5w6fw6q 5890 12 lower low JJR cord-006870-f5w6fw6q 5890 13 extremity extremity NN cord-006870-f5w6fw6q 5890 14 . . . cord-006870-f5w6fw6q 5891 1 He -PRON- PRP cord-006870-f5w6fw6q 5891 2 was be VBD cord-006870-f5w6fw6q 5891 3 treated treat VBN cord-006870-f5w6fw6q 5891 4 in in IN cord-006870-f5w6fw6q 5891 5 the the DT cord-006870-f5w6fw6q 5891 6 emergency emergency NN cord-006870-f5w6fw6q 5891 7 department department NN cord-006870-f5w6fw6q 5891 8 where where WRB cord-006870-f5w6fw6q 5891 9 the the DT cord-006870-f5w6fw6q 5891 10 wound wound NN cord-006870-f5w6fw6q 5891 11 was be VBD cord-006870-f5w6fw6q 5891 12 irrigated irrigate VBN cord-006870-f5w6fw6q 5891 13 and and CC cord-006870-f5w6fw6q 5891 14 closed closed JJ cord-006870-f5w6fw6q 5891 15 . . . cord-006870-f5w6fw6q 5892 1 Some some DT cord-006870-f5w6fw6q 5892 2 bullet bullet NN cord-006870-f5w6fw6q 5892 3 fragments fragment NNS cord-006870-f5w6fw6q 5892 4 could could MD cord-006870-f5w6fw6q 5892 5 not not RB cord-006870-f5w6fw6q 5892 6 be be VB cord-006870-f5w6fw6q 5892 7 retrieved retrieve VBN cord-006870-f5w6fw6q 5892 8 due due IN cord-006870-f5w6fw6q 5892 9 to to TO cord-006870-f5w6fw6q 5892 10 close close VB cord-006870-f5w6fw6q 5892 11 proximity proximity NN cord-006870-f5w6fw6q 5892 12 to to IN cord-006870-f5w6fw6q 5892 13 popliteal popliteal JJ cord-006870-f5w6fw6q 5892 14 vessels vessel NNS cord-006870-f5w6fw6q 5892 15 and and CC cord-006870-f5w6fw6q 5892 16 surrounding surround VBG cord-006870-f5w6fw6q 5892 17 nerves nerve NNS cord-006870-f5w6fw6q 5892 18 . . . cord-006870-f5w6fw6q 5893 1 He -PRON- PRP cord-006870-f5w6fw6q 5893 2 returned return VBD cord-006870-f5w6fw6q 5893 3 ten ten CD cord-006870-f5w6fw6q 5893 4 days day NNS cord-006870-f5w6fw6q 5893 5 later later RB cord-006870-f5w6fw6q 5893 6 with with IN cord-006870-f5w6fw6q 5893 7 diplopia diplopia NN cord-006870-f5w6fw6q 5893 8 and and CC cord-006870-f5w6fw6q 5893 9 nausea nausea NN cord-006870-f5w6fw6q 5893 10 . . . cord-006870-f5w6fw6q 5894 1 He -PRON- PRP cord-006870-f5w6fw6q 5894 2 denied deny VBD cord-006870-f5w6fw6q 5894 3 consumption consumption NN cord-006870-f5w6fw6q 5894 4 of of IN cord-006870-f5w6fw6q 5894 5 canned canned JJ cord-006870-f5w6fw6q 5894 6 foods food NNS cord-006870-f5w6fw6q 5894 7 or or CC cord-006870-f5w6fw6q 5894 8 illicit illicit JJ cord-006870-f5w6fw6q 5894 9 substances substance NNS cord-006870-f5w6fw6q 5894 10 and and CC cord-006870-f5w6fw6q 5894 11 had have VBD cord-006870-f5w6fw6q 5894 12 no no DT cord-006870-f5w6fw6q 5894 13 preceding precede VBG cord-006870-f5w6fw6q 5894 14 upper upper JJ cord-006870-f5w6fw6q 5894 15 respiratory respiratory JJ cord-006870-f5w6fw6q 5894 16 or or CC cord-006870-f5w6fw6q 5894 17 gastrointestinal gastrointestinal JJ cord-006870-f5w6fw6q 5894 18 illnesses illness NNS cord-006870-f5w6fw6q 5894 19 . . . cord-006870-f5w6fw6q 5895 1 On on IN cord-006870-f5w6fw6q 5895 2 examination examination NN cord-006870-f5w6fw6q 5895 3 , , , cord-006870-f5w6fw6q 5895 4 he -PRON- PRP cord-006870-f5w6fw6q 5895 5 exhibited exhibit VBD cord-006870-f5w6fw6q 5895 6 ptosis ptosis NN cord-006870-f5w6fw6q 5895 7 and and CC cord-006870-f5w6fw6q 5895 8 symmetric symmetric JJ cord-006870-f5w6fw6q 5895 9 bilateral bilateral JJ cord-006870-f5w6fw6q 5895 10 motor motor NN cord-006870-f5w6fw6q 5895 11 weakness weakness NN cord-006870-f5w6fw6q 5895 12 with with IN cord-006870-f5w6fw6q 5895 13 diminished diminish VBN cord-006870-f5w6fw6q 5895 14 deep deep JJ cord-006870-f5w6fw6q 5895 15 tendon tendon NN cord-006870-f5w6fw6q 5895 16 reflexes reflex NNS cord-006870-f5w6fw6q 5895 17 . . . cord-006870-f5w6fw6q 5896 1 The the DT cord-006870-f5w6fw6q 5896 2 GSW GSW NNP cord-006870-f5w6fw6q 5896 3 showed show VBD cord-006870-f5w6fw6q 5896 4 no no DT cord-006870-f5w6fw6q 5896 5 signs sign NNS cord-006870-f5w6fw6q 5896 6 of of IN cord-006870-f5w6fw6q 5896 7 infection infection NN cord-006870-f5w6fw6q 5896 8 . . . cord-006870-f5w6fw6q 5897 1 Progressive progressive JJ cord-006870-f5w6fw6q 5897 2 respiratory respiratory JJ cord-006870-f5w6fw6q 5897 3 insufficiency insufficiency NN cord-006870-f5w6fw6q 5897 4 resulted result VBD cord-006870-f5w6fw6q 5897 5 in in IN cord-006870-f5w6fw6q 5897 6 intubation intubation NN cord-006870-f5w6fw6q 5897 7 and and CC cord-006870-f5w6fw6q 5897 8 mechanical mechanical JJ cord-006870-f5w6fw6q 5897 9 ventilation ventilation NN cord-006870-f5w6fw6q 5897 10 . . . cord-006870-f5w6fw6q 5898 1 A a DT cord-006870-f5w6fw6q 5898 2 lumbar lumbar NN cord-006870-f5w6fw6q 5898 3 puncture puncture NN cord-006870-f5w6fw6q 5898 4 revealed reveal VBD cord-006870-f5w6fw6q 5898 5 normal normal JJ cord-006870-f5w6fw6q 5898 6 opening opening NN cord-006870-f5w6fw6q 5898 7 pressures pressure NNS cord-006870-f5w6fw6q 5898 8 and and CC cord-006870-f5w6fw6q 5898 9 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 5898 10 fluid fluid JJ cord-006870-f5w6fw6q 5898 11 analysis analysis NN cord-006870-f5w6fw6q 5898 12 was be VBD cord-006870-f5w6fw6q 5898 13 unremarkable unremarkable JJ cord-006870-f5w6fw6q 5898 14 . . . cord-006870-f5w6fw6q 5899 1 Titers Titers NNP cord-006870-f5w6fw6q 5899 2 for for IN cord-006870-f5w6fw6q 5899 3 acetylcholine acetylcholine NN cord-006870-f5w6fw6q 5899 4 receptor receptor NN cord-006870-f5w6fw6q 5899 5 and and CC cord-006870-f5w6fw6q 5899 6 anti anti JJ cord-006870-f5w6fw6q 5899 7 - - JJ cord-006870-f5w6fw6q 5899 8 muscle muscle JJ cord-006870-f5w6fw6q 5899 9 specific specific JJ cord-006870-f5w6fw6q 5899 10 kinase kinase NN cord-006870-f5w6fw6q 5899 11 antibodies antibody NNS cord-006870-f5w6fw6q 5899 12 were be VBD cord-006870-f5w6fw6q 5899 13 negative negative JJ cord-006870-f5w6fw6q 5899 14 , , , cord-006870-f5w6fw6q 5899 15 as as IN cord-006870-f5w6fw6q 5899 16 was be VBD cord-006870-f5w6fw6q 5899 17 a a DT cord-006870-f5w6fw6q 5899 18 tensilon tensilon NN cord-006870-f5w6fw6q 5899 19 test test NN cord-006870-f5w6fw6q 5899 20 . . . cord-006870-f5w6fw6q 5900 1 Blood blood NN cord-006870-f5w6fw6q 5900 2 toxicology toxicology NN cord-006870-f5w6fw6q 5900 3 analysis analysis NN cord-006870-f5w6fw6q 5900 4 showed show VBD cord-006870-f5w6fw6q 5900 5 no no DT cord-006870-f5w6fw6q 5900 6 evidence evidence NN cord-006870-f5w6fw6q 5900 7 of of IN cord-006870-f5w6fw6q 5900 8 illicit illicit JJ cord-006870-f5w6fw6q 5900 9 substances substance NNS cord-006870-f5w6fw6q 5900 10 or or CC cord-006870-f5w6fw6q 5900 11 heavy heavy JJ cord-006870-f5w6fw6q 5900 12 metal metal NN cord-006870-f5w6fw6q 5900 13 poisoning poisoning NN cord-006870-f5w6fw6q 5900 14 . . . cord-006870-f5w6fw6q 5901 1 A a DT cord-006870-f5w6fw6q 5901 2 high high JJ cord-006870-f5w6fw6q 5901 3 suspicion suspicion NN cord-006870-f5w6fw6q 5901 4 for for IN cord-006870-f5w6fw6q 5901 5 wound wound JJ cord-006870-f5w6fw6q 5901 6 botulism botulism NN cord-006870-f5w6fw6q 5901 7 led lead VBD cord-006870-f5w6fw6q 5901 8 to to IN cord-006870-f5w6fw6q 5901 9 consultation consultation NN cord-006870-f5w6fw6q 5901 10 with with IN cord-006870-f5w6fw6q 5901 11 the the DT cord-006870-f5w6fw6q 5901 12 regional regional JJ cord-006870-f5w6fw6q 5901 13 poison poison NN cord-006870-f5w6fw6q 5901 14 center center NN cord-006870-f5w6fw6q 5901 15 and and CC cord-006870-f5w6fw6q 5901 16 CDC CDC NNP cord-006870-f5w6fw6q 5901 17 . . . cord-006870-f5w6fw6q 5902 1 Blood blood NN cord-006870-f5w6fw6q 5902 2 and and CC cord-006870-f5w6fw6q 5902 3 anaerobic anaerobic JJ cord-006870-f5w6fw6q 5902 4 wound wound NN cord-006870-f5w6fw6q 5902 5 samples sample NNS cord-006870-f5w6fw6q 5902 6 were be VBD cord-006870-f5w6fw6q 5902 7 obtained obtain VBN cord-006870-f5w6fw6q 5902 8 for for IN cord-006870-f5w6fw6q 5902 9 toxin toxin NN cord-006870-f5w6fw6q 5902 10 bioassay bioassay NN cord-006870-f5w6fw6q 5902 11 and and CC cord-006870-f5w6fw6q 5902 12 culture culture NN cord-006870-f5w6fw6q 5902 13 . . . cord-006870-f5w6fw6q 5903 1 Empiric empiric NN cord-006870-f5w6fw6q 5903 2 intravenous intravenous JJ cord-006870-f5w6fw6q 5903 3 penicillin penicillin NN cord-006870-f5w6fw6q 5903 4 G G NNP cord-006870-f5w6fw6q 5903 5 therapy therapy NN cord-006870-f5w6fw6q 5903 6 was be VBD cord-006870-f5w6fw6q 5903 7 started start VBN cord-006870-f5w6fw6q 5903 8 . . . cord-006870-f5w6fw6q 5904 1 Equine Equine NNP cord-006870-f5w6fw6q 5904 2 Heptavalent Heptavalent NNP cord-006870-f5w6fw6q 5904 3 Antitoxin Antitoxin NNP cord-006870-f5w6fw6q 5904 4 ( ( -LRB- cord-006870-f5w6fw6q 5904 5 H h NN cord-006870-f5w6fw6q 5904 6 - - HYPH cord-006870-f5w6fw6q 5904 7 BAT bat NN cord-006870-f5w6fw6q 5904 8 ) ) -RRB- cord-006870-f5w6fw6q 5904 9 was be VBD cord-006870-f5w6fw6q 5904 10 obtained obtain VBN cord-006870-f5w6fw6q 5904 11 and and CC cord-006870-f5w6fw6q 5904 12 administered administer VBN cord-006870-f5w6fw6q 5904 13 on on IN cord-006870-f5w6fw6q 5904 14 hospital hospital NN cord-006870-f5w6fw6q 5904 15 day day NN cord-006870-f5w6fw6q 5904 16 2 2 CD cord-006870-f5w6fw6q 5904 17 . . . cord-006870-f5w6fw6q 5905 1 Serum serum NN cord-006870-f5w6fw6q 5905 2 toxin toxin NN cord-006870-f5w6fw6q 5905 3 bioassay bioassay NN cord-006870-f5w6fw6q 5905 4 tested test VBD cord-006870-f5w6fw6q 5905 5 positive positive JJ cord-006870-f5w6fw6q 5905 6 for for IN cord-006870-f5w6fw6q 5905 7 botulinum botulinum NN cord-006870-f5w6fw6q 5905 8 neurotoxin neurotoxin NN cord-006870-f5w6fw6q 5905 9 type type NN cord-006870-f5w6fw6q 5905 10 A. a. NN cord-006870-f5w6fw6q 5906 1 The the DT cord-006870-f5w6fw6q 5906 2 patient patient NN cord-006870-f5w6fw6q 5906 3 required require VBD cord-006870-f5w6fw6q 5906 4 a a DT cord-006870-f5w6fw6q 5906 5 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 5906 6 tube tube NN cord-006870-f5w6fw6q 5906 7 due due IN cord-006870-f5w6fw6q 5906 8 to to IN cord-006870-f5w6fw6q 5906 9 persistent persistent JJ cord-006870-f5w6fw6q 5906 10 dysphagia dysphagia NN cord-006870-f5w6fw6q 5906 11 . . . cord-006870-f5w6fw6q 5907 1 After after IN cord-006870-f5w6fw6q 5907 2 one one CD cord-006870-f5w6fw6q 5907 3 month month NN cord-006870-f5w6fw6q 5907 4 of of IN cord-006870-f5w6fw6q 5907 5 hospitalization hospitalization NN cord-006870-f5w6fw6q 5907 6 , , , cord-006870-f5w6fw6q 5907 7 he -PRON- PRP cord-006870-f5w6fw6q 5907 8 was be VBD cord-006870-f5w6fw6q 5907 9 discharged discharge VBN cord-006870-f5w6fw6q 5907 10 home home RB cord-006870-f5w6fw6q 5907 11 and and CC cord-006870-f5w6fw6q 5907 12 continues continue VBZ cord-006870-f5w6fw6q 5907 13 outpatient outpatient JJ cord-006870-f5w6fw6q 5907 14 physical physical JJ cord-006870-f5w6fw6q 5907 15 therapy therapy NN cord-006870-f5w6fw6q 5907 16 . . . cord-006870-f5w6fw6q 5908 1 Wound wound VB cord-006870-f5w6fw6q 5908 2 botulism botulism NN cord-006870-f5w6fw6q 5908 3 from from IN cord-006870-f5w6fw6q 5908 4 traumatic traumatic JJ cord-006870-f5w6fw6q 5908 5 injury injury NN cord-006870-f5w6fw6q 5908 6 is be VBZ cord-006870-f5w6fw6q 5908 7 exceedingly exceedingly RB cord-006870-f5w6fw6q 5908 8 rare rare JJ cord-006870-f5w6fw6q 5908 9 with with IN cord-006870-f5w6fw6q 5908 10 only only RB cord-006870-f5w6fw6q 5908 11 one one CD cord-006870-f5w6fw6q 5908 12 to to TO cord-006870-f5w6fw6q 5908 13 two two CD cord-006870-f5w6fw6q 5908 14 cases case NNS cord-006870-f5w6fw6q 5908 15 reported report VBN cord-006870-f5w6fw6q 5908 16 annually annually RB cord-006870-f5w6fw6q 5908 17 . . . cord-006870-f5w6fw6q 5909 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5909 2 case case NN cord-006870-f5w6fw6q 5909 3 is be VBZ cord-006870-f5w6fw6q 5909 4 the the DT cord-006870-f5w6fw6q 5909 5 first first JJ cord-006870-f5w6fw6q 5909 6 reported reported JJ cord-006870-f5w6fw6q 5909 7 incidence incidence NN cord-006870-f5w6fw6q 5909 8 of of IN cord-006870-f5w6fw6q 5909 9 wound wound JJ cord-006870-f5w6fw6q 5909 10 botulism botulism NN cord-006870-f5w6fw6q 5909 11 from from IN cord-006870-f5w6fw6q 5909 12 a a DT cord-006870-f5w6fw6q 5909 13 single single JJ cord-006870-f5w6fw6q 5909 14 gunshot gunshot NN cord-006870-f5w6fw6q 5909 15 wound wound NN cord-006870-f5w6fw6q 5909 16 . . . cord-006870-f5w6fw6q 5910 1 Hyperammonemic hyperammonemic JJ cord-006870-f5w6fw6q 5910 2 cerebral cerebral JJ cord-006870-f5w6fw6q 5910 3 edema edema NN cord-006870-f5w6fw6q 5910 4 ( ( -LRB- cord-006870-f5w6fw6q 5910 5 HCE HCE NNP cord-006870-f5w6fw6q 5910 6 ) ) -RRB- cord-006870-f5w6fw6q 5910 7 with with IN cord-006870-f5w6fw6q 5910 8 brain brain NN cord-006870-f5w6fw6q 5910 9 herniation herniation NN cord-006870-f5w6fw6q 5910 10 carries carry VBZ cord-006870-f5w6fw6q 5910 11 a a DT cord-006870-f5w6fw6q 5910 12 dismal dismal JJ cord-006870-f5w6fw6q 5910 13 prognosis prognosis NN cord-006870-f5w6fw6q 5910 14 historically historically RB cord-006870-f5w6fw6q 5910 15 despite despite IN cord-006870-f5w6fw6q 5910 16 aggressive aggressive JJ cord-006870-f5w6fw6q 5910 17 treatment treatment NN cord-006870-f5w6fw6q 5910 18 . . . cord-006870-f5w6fw6q 5911 1 However however RB cord-006870-f5w6fw6q 5911 2 , , , cord-006870-f5w6fw6q 5911 3 we -PRON- PRP cord-006870-f5w6fw6q 5911 4 report report VBP cord-006870-f5w6fw6q 5911 5 a a DT cord-006870-f5w6fw6q 5911 6 case case NN cord-006870-f5w6fw6q 5911 7 where where WRB cord-006870-f5w6fw6q 5911 8 a a DT cord-006870-f5w6fw6q 5911 9 patient patient NN cord-006870-f5w6fw6q 5911 10 with with IN cord-006870-f5w6fw6q 5911 11 severe severe JJ cord-006870-f5w6fw6q 5911 12 HCE HCE NNP cord-006870-f5w6fw6q 5911 13 and and CC cord-006870-f5w6fw6q 5911 14 herniation herniation NN cord-006870-f5w6fw6q 5911 15 returned return VBD cord-006870-f5w6fw6q 5911 16 to to IN cord-006870-f5w6fw6q 5911 17 her -PRON- PRP$ cord-006870-f5w6fw6q 5911 18 neurological neurological JJ cord-006870-f5w6fw6q 5911 19 baseline baseline NN cord-006870-f5w6fw6q 5911 20 after after IN cord-006870-f5w6fw6q 5911 21 aggressive aggressive JJ cord-006870-f5w6fw6q 5911 22 medical medical JJ cord-006870-f5w6fw6q 5911 23 management management NN cord-006870-f5w6fw6q 5911 24 . . . cord-006870-f5w6fw6q 5912 1 A a DT cord-006870-f5w6fw6q 5912 2 62-year 62-year JJ cord-006870-f5w6fw6q 5912 3 - - HYPH cord-006870-f5w6fw6q 5912 4 old old JJ cord-006870-f5w6fw6q 5912 5 woman woman NN cord-006870-f5w6fw6q 5912 6 became become VBD cord-006870-f5w6fw6q 5912 7 acutely acutely RB cord-006870-f5w6fw6q 5912 8 comatose comatose JJ cord-006870-f5w6fw6q 5912 9 with with IN cord-006870-f5w6fw6q 5912 10 a a DT cord-006870-f5w6fw6q 5912 11 blown blown JJ cord-006870-f5w6fw6q 5912 12 left left JJ cord-006870-f5w6fw6q 5912 13 pupil pupil NN cord-006870-f5w6fw6q 5912 14 and and CC cord-006870-f5w6fw6q 5912 15 required require VBD cord-006870-f5w6fw6q 5912 16 intubation intubation NN cord-006870-f5w6fw6q 5912 17 several several JJ cord-006870-f5w6fw6q 5912 18 days day NNS cord-006870-f5w6fw6q 5912 19 after after IN cord-006870-f5w6fw6q 5912 20 admission admission NN cord-006870-f5w6fw6q 5912 21 for for IN cord-006870-f5w6fw6q 5912 22 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5912 23 . . . cord-006870-f5w6fw6q 5913 1 Head Head NNP cord-006870-f5w6fw6q 5913 2 CT CT NNP cord-006870-f5w6fw6q 5913 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 5913 4 diffuse diffuse JJ cord-006870-f5w6fw6q 5913 5 cerebral cerebral JJ cord-006870-f5w6fw6q 5913 6 edema edema NN cord-006870-f5w6fw6q 5913 7 with with IN cord-006870-f5w6fw6q 5913 8 central central JJ cord-006870-f5w6fw6q 5913 9 and and CC cord-006870-f5w6fw6q 5913 10 bilateral bilateral JJ cord-006870-f5w6fw6q 5913 11 uncal uncal JJ cord-006870-f5w6fw6q 5913 12 herniation herniation NN cord-006870-f5w6fw6q 5913 13 . . . cord-006870-f5w6fw6q 5914 1 Profound profound JJ cord-006870-f5w6fw6q 5914 2 hyperammonemia hyperammonemia NN cord-006870-f5w6fw6q 5914 3 ( ( -LRB- cord-006870-f5w6fw6q 5914 4 238ug 238ug NNP cord-006870-f5w6fw6q 5914 5 / / SYM cord-006870-f5w6fw6q 5914 6 dL dl NN cord-006870-f5w6fw6q 5914 7 ) ) -RRB- cord-006870-f5w6fw6q 5914 8 was be VBD cord-006870-f5w6fw6q 5914 9 implicated implicate VBN cord-006870-f5w6fw6q 5914 10 , , , cord-006870-f5w6fw6q 5914 11 though though IN cord-006870-f5w6fw6q 5914 12 hepatic hepatic JJ cord-006870-f5w6fw6q 5914 13 function function NN cord-006870-f5w6fw6q 5914 14 was be VBD cord-006870-f5w6fw6q 5914 15 normal normal JJ cord-006870-f5w6fw6q 5914 16 . . . cord-006870-f5w6fw6q 5915 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 5915 2 intracranial intracranial JJ cord-006870-f5w6fw6q 5915 3 hypertension hypertension NN cord-006870-f5w6fw6q 5915 4 was be VBD cord-006870-f5w6fw6q 5915 5 ultimately ultimately RB cord-006870-f5w6fw6q 5915 6 controlled control VBN cord-006870-f5w6fw6q 5915 7 using use VBG cord-006870-f5w6fw6q 5915 8 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 5915 9 , , , cord-006870-f5w6fw6q 5915 10 sedation sedation NN cord-006870-f5w6fw6q 5915 11 , , , cord-006870-f5w6fw6q 5915 12 and and CC cord-006870-f5w6fw6q 5915 13 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 5915 14 , , , cord-006870-f5w6fw6q 5915 15 resulting result VBG cord-006870-f5w6fw6q 5915 16 normalization normalization NN cord-006870-f5w6fw6q 5915 17 of of IN cord-006870-f5w6fw6q 5915 18 her -PRON- PRP$ cord-006870-f5w6fw6q 5915 19 brainstem brainstem NN cord-006870-f5w6fw6q 5915 20 reflexes reflex NNS cord-006870-f5w6fw6q 5915 21 and and CC cord-006870-f5w6fw6q 5915 22 improvement improvement NN cord-006870-f5w6fw6q 5915 23 in in IN cord-006870-f5w6fw6q 5915 24 her -PRON- PRP$ cord-006870-f5w6fw6q 5915 25 coma coma NN cord-006870-f5w6fw6q 5915 26 and and CC cord-006870-f5w6fw6q 5915 27 imaging imaging NN cord-006870-f5w6fw6q 5915 28 . . . cord-006870-f5w6fw6q 5916 1 Continuous continuous JJ cord-006870-f5w6fw6q 5916 2 veno veno NNP cord-006870-f5w6fw6q 5916 3 - - HYPH cord-006870-f5w6fw6q 5916 4 venous venous JJ cord-006870-f5w6fw6q 5916 5 hemodialysis hemodialysis NN cord-006870-f5w6fw6q 5916 6 ( ( -LRB- cord-006870-f5w6fw6q 5916 7 CVVHD CVVHD NNP cord-006870-f5w6fw6q 5916 8 ) ) -RRB- cord-006870-f5w6fw6q 5916 9 normalized normalize VBD cord-006870-f5w6fw6q 5916 10 her -PRON- PRP$ cord-006870-f5w6fw6q 5916 11 ammonia ammonia NN cord-006870-f5w6fw6q 5916 12 and and CC cord-006870-f5w6fw6q 5916 13 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5916 14 that that WDT cord-006870-f5w6fw6q 5916 15 was be VBD cord-006870-f5w6fw6q 5916 16 initially initially RB cord-006870-f5w6fw6q 5916 17 refractory refractory JJ cord-006870-f5w6fw6q 5916 18 . . . cord-006870-f5w6fw6q 5917 1 Multiple multiple JJ cord-006870-f5w6fw6q 5917 2 porto porto JJ cord-006870-f5w6fw6q 5917 3 - - HYPH cord-006870-f5w6fw6q 5917 4 hepatic hepatic JJ cord-006870-f5w6fw6q 5917 5 shunts shunt NNS cord-006870-f5w6fw6q 5917 6 were be VBD cord-006870-f5w6fw6q 5917 7 identified identify VBN cord-006870-f5w6fw6q 5917 8 on on IN cord-006870-f5w6fw6q 5917 9 hepatic hepatic JJ cord-006870-f5w6fw6q 5917 10 CT CT NNP cord-006870-f5w6fw6q 5917 11 angiogram angiogram NN cord-006870-f5w6fw6q 5917 12 as as IN cord-006870-f5w6fw6q 5917 13 the the DT cord-006870-f5w6fw6q 5917 14 cause cause NN cord-006870-f5w6fw6q 5917 15 of of IN cord-006870-f5w6fw6q 5917 16 her -PRON- PRP$ cord-006870-f5w6fw6q 5917 17 hyperammonemia hyperammonemia NN cord-006870-f5w6fw6q 5917 18 , , , cord-006870-f5w6fw6q 5917 19 and and CC cord-006870-f5w6fw6q 5917 20 were be VBD cord-006870-f5w6fw6q 5917 21 embolized embolize VBN cord-006870-f5w6fw6q 5917 22 . . . cord-006870-f5w6fw6q 5918 1 She -PRON- PRP cord-006870-f5w6fw6q 5918 2 was be VBD cord-006870-f5w6fw6q 5918 3 eventually eventually RB cord-006870-f5w6fw6q 5918 4 weaned wean VBN cord-006870-f5w6fw6q 5918 5 off off RP cord-006870-f5w6fw6q 5918 6 CVVHD CVVHD NNP cord-006870-f5w6fw6q 5918 7 and and CC cord-006870-f5w6fw6q 5918 8 extubated extubate VBD cord-006870-f5w6fw6q 5918 9 , , , cord-006870-f5w6fw6q 5918 10 without without IN cord-006870-f5w6fw6q 5918 11 residual residual JJ cord-006870-f5w6fw6q 5918 12 neurological neurological JJ cord-006870-f5w6fw6q 5918 13 deficits deficit NNS cord-006870-f5w6fw6q 5918 14 . . . cord-006870-f5w6fw6q 5919 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 5919 2 case case NN cord-006870-f5w6fw6q 5919 3 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 5919 4 that that IN cord-006870-f5w6fw6q 5919 5 , , , cord-006870-f5w6fw6q 5919 6 with with IN cord-006870-f5w6fw6q 5919 7 contemporary contemporary JJ cord-006870-f5w6fw6q 5919 8 management management NN cord-006870-f5w6fw6q 5919 9 , , , cord-006870-f5w6fw6q 5919 10 clinical clinical JJ cord-006870-f5w6fw6q 5919 11 and and CC cord-006870-f5w6fw6q 5919 12 radiographic radiographic JJ cord-006870-f5w6fw6q 5919 13 reversal reversal NN cord-006870-f5w6fw6q 5919 14 of of IN cord-006870-f5w6fw6q 5919 15 HCE HCE NNP cord-006870-f5w6fw6q 5919 16 and and CC cord-006870-f5w6fw6q 5919 17 herniation herniation NN cord-006870-f5w6fw6q 5919 18 is be VBZ cord-006870-f5w6fw6q 5919 19 possible possible JJ cord-006870-f5w6fw6q 5919 20 and and CC cord-006870-f5w6fw6q 5919 21 prognosis prognosis NN cord-006870-f5w6fw6q 5919 22 is be VBZ cord-006870-f5w6fw6q 5919 23 not not RB cord-006870-f5w6fw6q 5919 24 uniformly uniformly RB cord-006870-f5w6fw6q 5919 25 poor poor JJ cord-006870-f5w6fw6q 5919 26 . . . cord-006870-f5w6fw6q 5920 1 Therefore therefore RB cord-006870-f5w6fw6q 5920 2 , , , cord-006870-f5w6fw6q 5920 3 neurological neurological JJ cord-006870-f5w6fw6q 5920 4 prognostication prognostication NN cord-006870-f5w6fw6q 5920 5 in in IN cord-006870-f5w6fw6q 5920 6 these these DT cord-006870-f5w6fw6q 5920 7 patients patient NNS cord-006870-f5w6fw6q 5920 8 should should MD cord-006870-f5w6fw6q 5920 9 only only RB cord-006870-f5w6fw6q 5920 10 be be VB cord-006870-f5w6fw6q 5920 11 performed perform VBN cord-006870-f5w6fw6q 5920 12 after after IN cord-006870-f5w6fw6q 5920 13 assessing assess VBG cord-006870-f5w6fw6q 5920 14 the the DT cord-006870-f5w6fw6q 5920 15 clinical clinical JJ cord-006870-f5w6fw6q 5920 16 trajectory trajectory NN cord-006870-f5w6fw6q 5920 17 following follow VBG cord-006870-f5w6fw6q 5920 18 cerebral cerebral JJ cord-006870-f5w6fw6q 5920 19 resuscitation resuscitation NN cord-006870-f5w6fw6q 5920 20 and and CC cord-006870-f5w6fw6q 5920 21 ammonia ammonia NN cord-006870-f5w6fw6q 5920 22 reduction reduction NN cord-006870-f5w6fw6q 5920 23 . . . cord-006870-f5w6fw6q 5921 1 Furthermore furthermore RB cord-006870-f5w6fw6q 5921 2 , , , cord-006870-f5w6fw6q 5921 3 our -PRON- PRP$ cord-006870-f5w6fw6q 5921 4 case case NN cord-006870-f5w6fw6q 5921 5 provides provide VBZ cord-006870-f5w6fw6q 5921 6 an an DT cord-006870-f5w6fw6q 5921 7 example example NN cord-006870-f5w6fw6q 5921 8 of of IN cord-006870-f5w6fw6q 5921 9 how how WRB cord-006870-f5w6fw6q 5921 10 CVVHD CVVHD NNP cord-006870-f5w6fw6q 5921 11 can can MD cord-006870-f5w6fw6q 5921 12 be be VB cord-006870-f5w6fw6q 5921 13 used use VBN cord-006870-f5w6fw6q 5921 14 to to TO cord-006870-f5w6fw6q 5921 15 reduce reduce VB cord-006870-f5w6fw6q 5921 16 refractory refractory JJ cord-006870-f5w6fw6q 5921 17 hyperammonemia hyperammonemia NN cord-006870-f5w6fw6q 5921 18 quickly quickly RB cord-006870-f5w6fw6q 5921 19 until until IN cord-006870-f5w6fw6q 5921 20 the the DT cord-006870-f5w6fw6q 5921 21 cause cause NN cord-006870-f5w6fw6q 5921 22 of of IN cord-006870-f5w6fw6q 5921 23 the the DT cord-006870-f5w6fw6q 5921 24 hyperammonemia hyperammonemia NN cord-006870-f5w6fw6q 5921 25 can can MD cord-006870-f5w6fw6q 5921 26 be be VB cord-006870-f5w6fw6q 5921 27 ascertained ascertain VBN cord-006870-f5w6fw6q 5921 28 and and CC cord-006870-f5w6fw6q 5921 29 addressed address VBN cord-006870-f5w6fw6q 5921 30 . . . cord-006870-f5w6fw6q 5922 1 Finally finally RB cord-006870-f5w6fw6q 5922 2 , , , cord-006870-f5w6fw6q 5922 3 this this DT cord-006870-f5w6fw6q 5922 4 is be VBZ cord-006870-f5w6fw6q 5922 5 the the DT cord-006870-f5w6fw6q 5922 6 first first JJ cord-006870-f5w6fw6q 5922 7 case case NN cord-006870-f5w6fw6q 5922 8 reported report VBN cord-006870-f5w6fw6q 5922 9 of of IN cord-006870-f5w6fw6q 5922 10 HCE HCE NNP cord-006870-f5w6fw6q 5922 11 secondary secondary JJ cord-006870-f5w6fw6q 5922 12 to to IN cord-006870-f5w6fw6q 5922 13 primary primary JJ cord-006870-f5w6fw6q 5922 14 portosystemic portosystemic JJ cord-006870-f5w6fw6q 5922 15 shunt shunt NN cord-006870-f5w6fw6q 5922 16 in in IN cord-006870-f5w6fw6q 5922 17 absence absence NN cord-006870-f5w6fw6q 5922 18 of of IN cord-006870-f5w6fw6q 5922 19 hepatic hepatic JJ cord-006870-f5w6fw6q 5922 20 disorder disorder NN cord-006870-f5w6fw6q 5922 21 ; ; , cord-006870-f5w6fw6q 5922 22 vascular vascular JJ cord-006870-f5w6fw6q 5922 23 imaging imaging NN cord-006870-f5w6fw6q 5922 24 of of IN cord-006870-f5w6fw6q 5922 25 the the DT cord-006870-f5w6fw6q 5922 26 liver liver NN cord-006870-f5w6fw6q 5922 27 should should MD cord-006870-f5w6fw6q 5922 28 be be VB cord-006870-f5w6fw6q 5922 29 considered consider VBN cord-006870-f5w6fw6q 5922 30 in in IN cord-006870-f5w6fw6q 5922 31 the the DT cord-006870-f5w6fw6q 5922 32 work work NN cord-006870-f5w6fw6q 5922 33 - - HYPH cord-006870-f5w6fw6q 5922 34 up up NN cord-006870-f5w6fw6q 5922 35 of of IN cord-006870-f5w6fw6q 5922 36 patients patient NNS cord-006870-f5w6fw6q 5922 37 with with IN cord-006870-f5w6fw6q 5922 38 hyperammonemia hyperammonemia NN cord-006870-f5w6fw6q 5922 39 . . . cord-006870-f5w6fw6q 5923 1 A a DT cord-006870-f5w6fw6q 5923 2 good good JJ cord-006870-f5w6fw6q 5923 3 neurological neurological JJ cord-006870-f5w6fw6q 5923 4 prognosis prognosis NN cord-006870-f5w6fw6q 5923 5 is be VBZ cord-006870-f5w6fw6q 5923 6 possible possible JJ cord-006870-f5w6fw6q 5923 7 for for IN cord-006870-f5w6fw6q 5923 8 patients patient NNS cord-006870-f5w6fw6q 5923 9 with with IN cord-006870-f5w6fw6q 5923 10 HCE HCE NNP cord-006870-f5w6fw6q 5923 11 and and CC cord-006870-f5w6fw6q 5923 12 cerebral cerebral JJ cord-006870-f5w6fw6q 5923 13 herniation herniation NN cord-006870-f5w6fw6q 5923 14 with with IN cord-006870-f5w6fw6q 5923 15 aggressive aggressive JJ cord-006870-f5w6fw6q 5923 16 management management NN cord-006870-f5w6fw6q 5923 17 that that WDT cord-006870-f5w6fw6q 5923 18 includes include VBZ cord-006870-f5w6fw6q 5923 19 reduction reduction NN cord-006870-f5w6fw6q 5923 20 of of IN cord-006870-f5w6fw6q 5923 21 ICP ICP NNP cord-006870-f5w6fw6q 5923 22 and and CC cord-006870-f5w6fw6q 5923 23 ammonia ammonia NN cord-006870-f5w6fw6q 5923 24 . . . cord-006870-f5w6fw6q 5924 1 CCVHD CCVHD NNP cord-006870-f5w6fw6q 5924 2 is be VBZ cord-006870-f5w6fw6q 5924 3 a a DT cord-006870-f5w6fw6q 5924 4 useful useful JJ cord-006870-f5w6fw6q 5924 5 adjunct adjunct NN cord-006870-f5w6fw6q 5924 6 to to TO cord-006870-f5w6fw6q 5924 7 treat treat VB cord-006870-f5w6fw6q 5924 8 refractory refractory JJ cord-006870-f5w6fw6q 5924 9 hyperammonemia hyperammonemia NN cord-006870-f5w6fw6q 5924 10 . . . cord-006870-f5w6fw6q 5925 1 A a DT cord-006870-f5w6fw6q 5925 2 porto porto JJ cord-006870-f5w6fw6q 5925 3 - - HYPH cord-006870-f5w6fw6q 5925 4 systemic systemic JJ cord-006870-f5w6fw6q 5925 5 shunt shunt NN cord-006870-f5w6fw6q 5925 6 should should MD cord-006870-f5w6fw6q 5925 7 be be VB cord-006870-f5w6fw6q 5925 8 considered consider VBN cord-006870-f5w6fw6q 5925 9 as as IN cord-006870-f5w6fw6q 5925 10 an an DT cord-006870-f5w6fw6q 5925 11 etiology etiology NN cord-006870-f5w6fw6q 5925 12 for for IN cord-006870-f5w6fw6q 5925 13 hyperammonemia hyperammonemia NN cord-006870-f5w6fw6q 5925 14 . . . cord-006870-f5w6fw6q 5926 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 5926 2 venous venous JJ cord-006870-f5w6fw6q 5926 3 sinus sinus NN cord-006870-f5w6fw6q 5926 4 thrombosis thrombosis NN cord-006870-f5w6fw6q 5926 5 ( ( -LRB- cord-006870-f5w6fw6q 5926 6 CVST CVST NNP cord-006870-f5w6fw6q 5926 7 ) ) -RRB- cord-006870-f5w6fw6q 5926 8 often often RB cord-006870-f5w6fw6q 5926 9 presents present VBZ cord-006870-f5w6fw6q 5926 10 with with IN cord-006870-f5w6fw6q 5926 11 intracerebral intracerebral JJ cord-006870-f5w6fw6q 5926 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5926 13 and and CC cord-006870-f5w6fw6q 5926 14 seizures seizure NNS cord-006870-f5w6fw6q 5926 15 . . . cord-006870-f5w6fw6q 5927 1 Extensive extensive JJ cord-006870-f5w6fw6q 5927 2 involvement involvement NN cord-006870-f5w6fw6q 5927 3 of of IN cord-006870-f5w6fw6q 5927 4 the the DT cord-006870-f5w6fw6q 5927 5 cerebral cerebral JJ cord-006870-f5w6fw6q 5927 6 sinuses sinus NNS cord-006870-f5w6fw6q 5927 7 can can MD cord-006870-f5w6fw6q 5927 8 lead lead VB cord-006870-f5w6fw6q 5927 9 to to IN cord-006870-f5w6fw6q 5927 10 comatose comatose JJ cord-006870-f5w6fw6q 5927 11 state state NN cord-006870-f5w6fw6q 5927 12 due due JJ cord-006870-f5w6fw6q 5927 13 to to IN cord-006870-f5w6fw6q 5927 14 cerebral cerebral JJ cord-006870-f5w6fw6q 5927 15 edema edema NN cord-006870-f5w6fw6q 5927 16 and and CC cord-006870-f5w6fw6q 5927 17 associated associate VBN cord-006870-f5w6fw6q 5927 18 intracranial intracranial JJ cord-006870-f5w6fw6q 5927 19 hypertension hypertension NN cord-006870-f5w6fw6q 5927 20 . . . cord-006870-f5w6fw6q 5928 1 If if IN cord-006870-f5w6fw6q 5928 2 not not RB cord-006870-f5w6fw6q 5928 3 reversed reverse VBN cord-006870-f5w6fw6q 5928 4 with with IN cord-006870-f5w6fw6q 5928 5 early early JJ cord-006870-f5w6fw6q 5928 6 therapeutic therapeutic JJ cord-006870-f5w6fw6q 5928 7 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5928 8 , , , cord-006870-f5w6fw6q 5928 9 then then RB cord-006870-f5w6fw6q 5928 10 mechanical mechanical JJ cord-006870-f5w6fw6q 5928 11 thrombectomy thrombectomy NNP cord-006870-f5w6fw6q 5928 12 and and CC cord-006870-f5w6fw6q 5928 13 decompressive decompressive NNP cord-006870-f5w6fw6q 5928 14 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 5928 15 ( ( -LRB- cord-006870-f5w6fw6q 5928 16 DHC DHC NNP cord-006870-f5w6fw6q 5928 17 ) ) -RRB- cord-006870-f5w6fw6q 5928 18 may may MD cord-006870-f5w6fw6q 5928 19 be be VB cord-006870-f5w6fw6q 5928 20 necessary necessary JJ cord-006870-f5w6fw6q 5928 21 as as IN cord-006870-f5w6fw6q 5928 22 life life NN cord-006870-f5w6fw6q 5928 23 - - HYPH cord-006870-f5w6fw6q 5928 24 saving save VBG cord-006870-f5w6fw6q 5928 25 measures measure NNS cord-006870-f5w6fw6q 5928 26 . . . cord-006870-f5w6fw6q 5929 1 However however RB cord-006870-f5w6fw6q 5929 2 , , , cord-006870-f5w6fw6q 5929 3 etiological etiological JJ cord-006870-f5w6fw6q 5929 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 5929 5 of of IN cord-006870-f5w6fw6q 5929 6 associated associate VBN cord-006870-f5w6fw6q 5929 7 hypercoagulable hypercoagulable JJ cord-006870-f5w6fw6q 5929 8 state state NN cord-006870-f5w6fw6q 5929 9 is be VBZ cord-006870-f5w6fw6q 5929 10 needed need VBN cord-006870-f5w6fw6q 5929 11 for for IN cord-006870-f5w6fw6q 5929 12 successful successful JJ cord-006870-f5w6fw6q 5929 13 long long JJ cord-006870-f5w6fw6q 5929 14 - - HYPH cord-006870-f5w6fw6q 5929 15 term term NN cord-006870-f5w6fw6q 5929 16 treatment treatment NN cord-006870-f5w6fw6q 5929 17 . . . cord-006870-f5w6fw6q 5930 1 Case case NN cord-006870-f5w6fw6q 5930 2 report report NN cord-006870-f5w6fw6q 5930 3 of of IN cord-006870-f5w6fw6q 5930 4 a a DT cord-006870-f5w6fw6q 5930 5 patient patient NN cord-006870-f5w6fw6q 5930 6 presenting present VBG cord-006870-f5w6fw6q 5930 7 with with IN cord-006870-f5w6fw6q 5930 8 CVST CVST NNP cord-006870-f5w6fw6q 5930 9 requiring require VBG cord-006870-f5w6fw6q 5930 10 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5930 11 , , , cord-006870-f5w6fw6q 5930 12 DHC DHC NNP cord-006870-f5w6fw6q 5930 13 and and CC cord-006870-f5w6fw6q 5930 14 total total JJ cord-006870-f5w6fw6q 5930 15 colectomy colectomy NN cord-006870-f5w6fw6q 5930 16 ( ( -LRB- cord-006870-f5w6fw6q 5930 17 to to TO cord-006870-f5w6fw6q 5930 18 treat treat VB cord-006870-f5w6fw6q 5930 19 underlying underlie VBG cord-006870-f5w6fw6q 5930 20 ulcerative ulcerative JJ cord-006870-f5w6fw6q 5930 21 colitis colitis NN cord-006870-f5w6fw6q 5930 22 ) ) -RRB- cord-006870-f5w6fw6q 5930 23 as as IN cord-006870-f5w6fw6q 5930 24 treatment treatment NN cord-006870-f5w6fw6q 5930 25 with with IN cord-006870-f5w6fw6q 5930 26 full full JJ cord-006870-f5w6fw6q 5930 27 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5930 28 was be VBD cord-006870-f5w6fw6q 5930 29 associated associate VBN cord-006870-f5w6fw6q 5930 30 with with IN cord-006870-f5w6fw6q 5930 31 lifethreatening lifethreatene VBG cord-006870-f5w6fw6q 5930 32 hematochezia hematochezia NNP cord-006870-f5w6fw6q 5930 33 . . . cord-006870-f5w6fw6q 5931 1 Twenty twenty CD cord-006870-f5w6fw6q 5931 2 - - HYPH cord-006870-f5w6fw6q 5931 3 five five CD cord-006870-f5w6fw6q 5931 4 year year NN cord-006870-f5w6fw6q 5931 5 old old JJ cord-006870-f5w6fw6q 5931 6 man man NN cord-006870-f5w6fw6q 5931 7 with with IN cord-006870-f5w6fw6q 5931 8 one one CD cord-006870-f5w6fw6q 5931 9 week week NN cord-006870-f5w6fw6q 5931 10 history history NN cord-006870-f5w6fw6q 5931 11 of of IN cord-006870-f5w6fw6q 5931 12 diarrhea diarrhea NN cord-006870-f5w6fw6q 5931 13 presented present VBN cord-006870-f5w6fw6q 5931 14 with with IN cord-006870-f5w6fw6q 5931 15 left left JJ cord-006870-f5w6fw6q 5931 16 sided sided JJ cord-006870-f5w6fw6q 5931 17 weakness weakness NN cord-006870-f5w6fw6q 5931 18 . . . cord-006870-f5w6fw6q 5932 1 Imaging imaging NN cord-006870-f5w6fw6q 5932 2 studies study NNS cord-006870-f5w6fw6q 5932 3 confirmed confirm VBD cord-006870-f5w6fw6q 5932 4 extensive extensive JJ cord-006870-f5w6fw6q 5932 5 CVST CVST NNP cord-006870-f5w6fw6q 5932 6 with with IN cord-006870-f5w6fw6q 5932 7 minimal minimal JJ cord-006870-f5w6fw6q 5932 8 venous venous JJ cord-006870-f5w6fw6q 5932 9 drainage drainage NN cord-006870-f5w6fw6q 5932 10 through through IN cord-006870-f5w6fw6q 5932 11 bilateral bilateral JJ cord-006870-f5w6fw6q 5932 12 cavernous cavernous JJ cord-006870-f5w6fw6q 5932 13 sinuses sinus NNS cord-006870-f5w6fw6q 5932 14 as as RB cord-006870-f5w6fw6q 5932 15 well well RB cord-006870-f5w6fw6q 5932 16 as as IN cord-006870-f5w6fw6q 5932 17 right right JJ cord-006870-f5w6fw6q 5932 18 hemiparesis hemiparesis NN cord-006870-f5w6fw6q 5932 19 secondary secondary JJ cord-006870-f5w6fw6q 5932 20 to to IN cord-006870-f5w6fw6q 5932 21 left left JJ cord-006870-f5w6fw6q 5932 22 post post JJ cord-006870-f5w6fw6q 5932 23 cingulate cingulate NN cord-006870-f5w6fw6q 5932 24 intracranial intracranial JJ cord-006870-f5w6fw6q 5932 25 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 5932 26 . . . cord-006870-f5w6fw6q 5933 1 Patient Patient NNP cord-006870-f5w6fw6q 5933 2 subsequently subsequently RB cord-006870-f5w6fw6q 5933 3 developed develop VBD cord-006870-f5w6fw6q 5933 4 loss loss NN cord-006870-f5w6fw6q 5933 5 of of IN cord-006870-f5w6fw6q 5933 6 vision vision NN cord-006870-f5w6fw6q 5933 7 and and CC cord-006870-f5w6fw6q 5933 8 became become VBD cord-006870-f5w6fw6q 5933 9 encephalopathic encephalopathic JJ cord-006870-f5w6fw6q 5933 10 , , , cord-006870-f5w6fw6q 5933 11 despite despite IN cord-006870-f5w6fw6q 5933 12 initiation initiation NN cord-006870-f5w6fw6q 5933 13 of of IN cord-006870-f5w6fw6q 5933 14 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5933 15 with with IN cord-006870-f5w6fw6q 5933 16 heparin heparin NN cord-006870-f5w6fw6q 5933 17 . . . cord-006870-f5w6fw6q 5934 1 Hence hence RB cord-006870-f5w6fw6q 5934 2 , , , cord-006870-f5w6fw6q 5934 3 mechanical mechanical JJ cord-006870-f5w6fw6q 5934 4 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 5934 5 was be VBD cord-006870-f5w6fw6q 5934 6 attempted attempt VBN cord-006870-f5w6fw6q 5934 7 but but CC cord-006870-f5w6fw6q 5934 8 was be VBD cord-006870-f5w6fw6q 5934 9 unsuccessful unsuccessful JJ cord-006870-f5w6fw6q 5934 10 . . . cord-006870-f5w6fw6q 5935 1 He -PRON- PRP cord-006870-f5w6fw6q 5935 2 also also RB cord-006870-f5w6fw6q 5935 3 developed develop VBD cord-006870-f5w6fw6q 5935 4 consumptive consumptive JJ cord-006870-f5w6fw6q 5935 5 thrombocytopenia thrombocytopenia NN cord-006870-f5w6fw6q 5935 6 for for IN cord-006870-f5w6fw6q 5935 7 which which WDT cord-006870-f5w6fw6q 5935 8 his -PRON- PRP$ cord-006870-f5w6fw6q 5935 9 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5935 10 was be VBD cord-006870-f5w6fw6q 5935 11 switched switch VBN cord-006870-f5w6fw6q 5935 12 to to IN cord-006870-f5w6fw6q 5935 13 argatroban argatroban NNP cord-006870-f5w6fw6q 5935 14 . . . cord-006870-f5w6fw6q 5936 1 Progressive progressive JJ cord-006870-f5w6fw6q 5936 2 neurologic neurologic JJ cord-006870-f5w6fw6q 5936 3 deterioration deterioration NN cord-006870-f5w6fw6q 5936 4 necessitated necessitate VBD cord-006870-f5w6fw6q 5936 5 DHC DHC NNP cord-006870-f5w6fw6q 5936 6 . . . cord-006870-f5w6fw6q 5937 1 His -PRON- PRP$ cord-006870-f5w6fw6q 5937 2 neurological neurological JJ cord-006870-f5w6fw6q 5937 3 examination examination NN cord-006870-f5w6fw6q 5937 4 progressively progressively RB cord-006870-f5w6fw6q 5937 5 improved improve VBN cord-006870-f5w6fw6q 5937 6 upon upon IN cord-006870-f5w6fw6q 5937 7 re re NN cord-006870-f5w6fw6q 5937 8 - - NN cord-006870-f5w6fw6q 5937 9 initiation initiation NN cord-006870-f5w6fw6q 5937 10 of of IN cord-006870-f5w6fw6q 5937 11 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5937 12 resulting result VBG cord-006870-f5w6fw6q 5937 13 in in IN cord-006870-f5w6fw6q 5937 14 restoration restoration NN cord-006870-f5w6fw6q 5937 15 of of IN cord-006870-f5w6fw6q 5937 16 vision vision NN cord-006870-f5w6fw6q 5937 17 and and CC cord-006870-f5w6fw6q 5937 18 resolution resolution NN cord-006870-f5w6fw6q 5937 19 of of IN cord-006870-f5w6fw6q 5937 20 left left JJ cord-006870-f5w6fw6q 5937 21 hemiparesis hemiparesis NN cord-006870-f5w6fw6q 5937 22 . . . cord-006870-f5w6fw6q 5938 1 Later later RB cord-006870-f5w6fw6q 5938 2 in in IN cord-006870-f5w6fw6q 5938 3 the the DT cord-006870-f5w6fw6q 5938 4 disease disease NN cord-006870-f5w6fw6q 5938 5 course course NN cord-006870-f5w6fw6q 5938 6 , , , cord-006870-f5w6fw6q 5938 7 he -PRON- PRP cord-006870-f5w6fw6q 5938 8 developed develop VBD cord-006870-f5w6fw6q 5938 9 symptomatic symptomatic JJ cord-006870-f5w6fw6q 5938 10 hematochezia hematochezia NN cord-006870-f5w6fw6q 5938 11 associated associate VBN cord-006870-f5w6fw6q 5938 12 with with IN cord-006870-f5w6fw6q 5938 13 his -PRON- PRP$ cord-006870-f5w6fw6q 5938 14 primary primary JJ cord-006870-f5w6fw6q 5938 15 disease disease NN cord-006870-f5w6fw6q 5938 16 , , , cord-006870-f5w6fw6q 5938 17 ulcerative ulcerative JJ cord-006870-f5w6fw6q 5938 18 colitis colitis NN cord-006870-f5w6fw6q 5938 19 and and CC cord-006870-f5w6fw6q 5938 20 required require VBD cord-006870-f5w6fw6q 5938 21 total total JJ cord-006870-f5w6fw6q 5938 22 colectomy colectomy NN cord-006870-f5w6fw6q 5938 23 . . . cord-006870-f5w6fw6q 5939 1 Subsequently subsequently RB cord-006870-f5w6fw6q 5939 2 he -PRON- PRP cord-006870-f5w6fw6q 5939 3 was be VBD cord-006870-f5w6fw6q 5939 4 transitioned transition VBN cord-006870-f5w6fw6q 5939 5 to to IN cord-006870-f5w6fw6q 5939 6 oral oral JJ cord-006870-f5w6fw6q 5939 7 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 5939 8 and and CC cord-006870-f5w6fw6q 5939 9 transferred transfer VBN cord-006870-f5w6fw6q 5939 10 to to IN cord-006870-f5w6fw6q 5939 11 inpatient inpatient JJ cord-006870-f5w6fw6q 5939 12 rehabilitation rehabilitation NN cord-006870-f5w6fw6q 5939 13 facility facility NN cord-006870-f5w6fw6q 5939 14 due due IN cord-006870-f5w6fw6q 5939 15 to to IN cord-006870-f5w6fw6q 5939 16 deconditioning deconditione VBG cord-006870-f5w6fw6q 5939 17 from from IN cord-006870-f5w6fw6q 5939 18 prolonged prolonged JJ cord-006870-f5w6fw6q 5939 19 hospitalization hospitalization NN cord-006870-f5w6fw6q 5939 20 . . . cord-006870-f5w6fw6q 5940 1 CVST CVST NNP cord-006870-f5w6fw6q 5940 2 can can MD cord-006870-f5w6fw6q 5940 3 be be VB cord-006870-f5w6fw6q 5940 4 life life NN cord-006870-f5w6fw6q 5940 5 - - HYPH cord-006870-f5w6fw6q 5940 6 threatening threaten VBG cord-006870-f5w6fw6q 5940 7 unless unless IN cord-006870-f5w6fw6q 5940 8 early early JJ cord-006870-f5w6fw6q 5940 9 treatment treatment NN cord-006870-f5w6fw6q 5940 10 is be VBZ cord-006870-f5w6fw6q 5940 11 initiated initiate VBN cord-006870-f5w6fw6q 5940 12 . . . cord-006870-f5w6fw6q 5941 1 Appropriate appropriate JJ cord-006870-f5w6fw6q 5941 2 and and CC cord-006870-f5w6fw6q 5941 3 timely timely JJ cord-006870-f5w6fw6q 5941 4 treatment treatment NN cord-006870-f5w6fw6q 5941 5 including include VBG cord-006870-f5w6fw6q 5941 6 etiological etiological JJ cord-006870-f5w6fw6q 5941 7 diagnosis diagnosis NN cord-006870-f5w6fw6q 5941 8 can can MD cord-006870-f5w6fw6q 5941 9 lead lead VB cord-006870-f5w6fw6q 5941 10 to to IN cord-006870-f5w6fw6q 5941 11 favorable favorable JJ cord-006870-f5w6fw6q 5941 12 patient patient JJ cord-006870-f5w6fw6q 5941 13 outcomes outcome NNS cord-006870-f5w6fw6q 5941 14 . . . cord-006870-f5w6fw6q 5942 1 Adverse adverse JJ cord-006870-f5w6fw6q 5942 2 effects effect NNS cord-006870-f5w6fw6q 5942 3 of of IN cord-006870-f5w6fw6q 5942 4 intrathecal intrathecal JJ cord-006870-f5w6fw6q 5942 5 non non JJ cord-006870-f5w6fw6q 5942 6 - - JJ cord-006870-f5w6fw6q 5942 7 ionic ionic JJ cord-006870-f5w6fw6q 5942 8 contrast contrast NN cord-006870-f5w6fw6q 5942 9 during during IN cord-006870-f5w6fw6q 5942 10 myelography myelography NN cord-006870-f5w6fw6q 5942 11 are be VBP cord-006870-f5w6fw6q 5942 12 rare rare JJ cord-006870-f5w6fw6q 5942 13 but but CC cord-006870-f5w6fw6q 5942 14 can can MD cord-006870-f5w6fw6q 5942 15 include include VB cord-006870-f5w6fw6q 5942 16 seizures seizure NNS cord-006870-f5w6fw6q 5942 17 and and CC cord-006870-f5w6fw6q 5942 18 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5942 19 . . . cord-006870-f5w6fw6q 5943 1 To to IN cord-006870-f5w6fw6q 5943 2 our -PRON- PRP$ cord-006870-f5w6fw6q 5943 3 knowledge knowledge NN cord-006870-f5w6fw6q 5943 4 , , , cord-006870-f5w6fw6q 5943 5 cerebral cerebral JJ cord-006870-f5w6fw6q 5943 6 edema edema NN cord-006870-f5w6fw6q 5943 7 has have VBZ cord-006870-f5w6fw6q 5943 8 only only RB cord-006870-f5w6fw6q 5943 9 been be VBN cord-006870-f5w6fw6q 5943 10 reported report VBN cord-006870-f5w6fw6q 5943 11 in in IN cord-006870-f5w6fw6q 5943 12 the the DT cord-006870-f5w6fw6q 5943 13 literature literature NN cord-006870-f5w6fw6q 5943 14 in in IN cord-006870-f5w6fw6q 5943 15 two two CD cord-006870-f5w6fw6q 5943 16 previous previous JJ cord-006870-f5w6fw6q 5943 17 cases case NNS cord-006870-f5w6fw6q 5943 18 . . . cord-006870-f5w6fw6q 5944 1 We -PRON- PRP cord-006870-f5w6fw6q 5944 2 report report VBP cord-006870-f5w6fw6q 5944 3 a a DT cord-006870-f5w6fw6q 5944 4 case case NN cord-006870-f5w6fw6q 5944 5 of of IN cord-006870-f5w6fw6q 5944 6 malignant malignant JJ cord-006870-f5w6fw6q 5944 7 cerebral cerebral JJ cord-006870-f5w6fw6q 5944 8 edema edema NN cord-006870-f5w6fw6q 5944 9 following follow VBG cord-006870-f5w6fw6q 5944 10 intrathecal intrathecal JJ cord-006870-f5w6fw6q 5944 11 administration administration NN cord-006870-f5w6fw6q 5944 12 of of IN cord-006870-f5w6fw6q 5944 13 non non JJ cord-006870-f5w6fw6q 5944 14 - - JJ cord-006870-f5w6fw6q 5944 15 ionic ionic JJ cord-006870-f5w6fw6q 5944 16 contrast contrast NN cord-006870-f5w6fw6q 5944 17 who who WP cord-006870-f5w6fw6q 5944 18 developed develop VBD cord-006870-f5w6fw6q 5944 19 seizure seizure NN cord-006870-f5w6fw6q 5944 20 like like IN cord-006870-f5w6fw6q 5944 21 activity activity NN cord-006870-f5w6fw6q 5944 22 with with IN cord-006870-f5w6fw6q 5944 23 radiographic radiographic JJ cord-006870-f5w6fw6q 5944 24 evidence evidence NN cord-006870-f5w6fw6q 5944 25 on on IN cord-006870-f5w6fw6q 5944 26 a a DT cord-006870-f5w6fw6q 5944 27 head head NN cord-006870-f5w6fw6q 5944 28 computerized computerized NN cord-006870-f5w6fw6q 5944 29 tomography tomography NN cord-006870-f5w6fw6q 5944 30 ( ( -LRB- cord-006870-f5w6fw6q 5944 31 CT CT NNP cord-006870-f5w6fw6q 5944 32 ) ) -RRB- cord-006870-f5w6fw6q 5944 33 scan scan NN cord-006870-f5w6fw6q 5944 34 of of IN cord-006870-f5w6fw6q 5944 35 acute acute JJ cord-006870-f5w6fw6q 5944 36 diffuse diffuse JJ cord-006870-f5w6fw6q 5944 37 cerebral cerebral JJ cord-006870-f5w6fw6q 5944 38 edema edema NN cord-006870-f5w6fw6q 5944 39 . . . cord-006870-f5w6fw6q 5945 1 An an DT cord-006870-f5w6fw6q 5945 2 80 80 CD cord-006870-f5w6fw6q 5945 3 year year NN cord-006870-f5w6fw6q 5945 4 - - HYPH cord-006870-f5w6fw6q 5945 5 old old JJ cord-006870-f5w6fw6q 5945 6 male male NN cord-006870-f5w6fw6q 5945 7 underwent undergo VBD cord-006870-f5w6fw6q 5945 8 an an DT cord-006870-f5w6fw6q 5945 9 elective elective JJ cord-006870-f5w6fw6q 5945 10 spinal spinal JJ cord-006870-f5w6fw6q 5945 11 CT CT NNP cord-006870-f5w6fw6q 5945 12 myelogram myelogram NN cord-006870-f5w6fw6q 5945 13 using use VBG cord-006870-f5w6fw6q 5945 14 20 20 CD cord-006870-f5w6fw6q 5945 15 mm mm NNS cord-006870-f5w6fw6q 5945 16 of of IN cord-006870-f5w6fw6q 5945 17 Isovue Isovue NNP cord-006870-f5w6fw6q 5945 18 M M NNP cord-006870-f5w6fw6q 5945 19 200 200 CD cord-006870-f5w6fw6q 5945 20 non non JJ cord-006870-f5w6fw6q 5945 21 - - JJ cord-006870-f5w6fw6q 5945 22 ionic ionic JJ cord-006870-f5w6fw6q 5945 23 contrast contrast NN cord-006870-f5w6fw6q 5945 24 to to TO cord-006870-f5w6fw6q 5945 25 evaluate evaluate VB cord-006870-f5w6fw6q 5945 26 chronic chronic JJ cord-006870-f5w6fw6q 5945 27 lumbar lumbar NN cord-006870-f5w6fw6q 5945 28 pain pain NN cord-006870-f5w6fw6q 5945 29 related relate VBN cord-006870-f5w6fw6q 5945 30 to to IN cord-006870-f5w6fw6q 5945 31 spinal spinal JJ cord-006870-f5w6fw6q 5945 32 stenosis stenosis NN cord-006870-f5w6fw6q 5945 33 . . . cord-006870-f5w6fw6q 5946 1 No no DT cord-006870-f5w6fw6q 5946 2 complications complication NNS cord-006870-f5w6fw6q 5946 3 were be VBD cord-006870-f5w6fw6q 5946 4 reported report VBN cord-006870-f5w6fw6q 5946 5 intra intra RB cord-006870-f5w6fw6q 5946 6 - - JJ cord-006870-f5w6fw6q 5946 7 procedurally procedurally RB cord-006870-f5w6fw6q 5946 8 and and CC cord-006870-f5w6fw6q 5946 9 the the DT cord-006870-f5w6fw6q 5946 10 patient patient NN cord-006870-f5w6fw6q 5946 11 was be VBD cord-006870-f5w6fw6q 5946 12 discharged discharge VBN cord-006870-f5w6fw6q 5946 13 home home RB cord-006870-f5w6fw6q 5946 14 . . . cord-006870-f5w6fw6q 5947 1 The the DT cord-006870-f5w6fw6q 5947 2 patient patient NN cord-006870-f5w6fw6q 5947 3 began begin VBD cord-006870-f5w6fw6q 5947 4 to to TO cord-006870-f5w6fw6q 5947 5 complain complain VB cord-006870-f5w6fw6q 5947 6 of of IN cord-006870-f5w6fw6q 5947 7 progressive progressive JJ cord-006870-f5w6fw6q 5947 8 worsening worsen VBG cord-006870-f5w6fw6q 5947 9 headaches headache NNS cord-006870-f5w6fw6q 5947 10 . . . cord-006870-f5w6fw6q 5948 1 The the DT cord-006870-f5w6fw6q 5948 2 following following JJ cord-006870-f5w6fw6q 5948 3 morning morning NN cord-006870-f5w6fw6q 5948 4 he -PRON- PRP cord-006870-f5w6fw6q 5948 5 started start VBD cord-006870-f5w6fw6q 5948 6 complaining complain VBG cord-006870-f5w6fw6q 5948 7 of of IN cord-006870-f5w6fw6q 5948 8 nausea nausea NN cord-006870-f5w6fw6q 5948 9 / / SYM cord-006870-f5w6fw6q 5948 10 vomiting vomiting NN cord-006870-f5w6fw6q 5948 11 , , , cord-006870-f5w6fw6q 5948 12 lost lose VBD cord-006870-f5w6fw6q 5948 13 consciousness consciousness NN cord-006870-f5w6fw6q 5948 14 with with IN cord-006870-f5w6fw6q 5948 15 posturing posturing NN cord-006870-f5w6fw6q 5948 16 vs vs IN cord-006870-f5w6fw6q 5948 17 seizure seizure NN cord-006870-f5w6fw6q 5948 18 like like IN cord-006870-f5w6fw6q 5948 19 activity activity NN cord-006870-f5w6fw6q 5948 20 . . . cord-006870-f5w6fw6q 5949 1 A a DT cord-006870-f5w6fw6q 5949 2 head head NN cord-006870-f5w6fw6q 5949 3 CT CT NNP cord-006870-f5w6fw6q 5949 4 revealed reveal VBD cord-006870-f5w6fw6q 5949 5 extensive extensive JJ cord-006870-f5w6fw6q 5949 6 brain brain NN cord-006870-f5w6fw6q 5949 7 edema edema NN cord-006870-f5w6fw6q 5949 8 and and CC cord-006870-f5w6fw6q 5949 9 swelling swell VBG cord-006870-f5w6fw6q 5949 10 with with IN cord-006870-f5w6fw6q 5949 11 crowding crowding NN cord-006870-f5w6fw6q 5949 12 of of IN cord-006870-f5w6fw6q 5949 13 the the DT cord-006870-f5w6fw6q 5949 14 brainstem brainstem NN cord-006870-f5w6fw6q 5949 15 and and CC cord-006870-f5w6fw6q 5949 16 herniation herniation NNP cord-006870-f5w6fw6q 5949 17 ( ( -LRB- cord-006870-f5w6fw6q 5949 18 fig fig NN cord-006870-f5w6fw6q 5949 19 . . NNP cord-006870-f5w6fw6q 5949 20 1 1 CD cord-006870-f5w6fw6q 5949 21 ) ) -RRB- cord-006870-f5w6fw6q 5949 22 . . . cord-006870-f5w6fw6q 5950 1 This this DT cord-006870-f5w6fw6q 5950 2 patient patient NN cord-006870-f5w6fw6q 5950 3 was be VBD cord-006870-f5w6fw6q 5950 4 intubated intubate VBN cord-006870-f5w6fw6q 5950 5 and and CC cord-006870-f5w6fw6q 5950 6 given give VBN cord-006870-f5w6fw6q 5950 7 an an DT cord-006870-f5w6fw6q 5950 8 IV IV NNP cord-006870-f5w6fw6q 5950 9 mannitol mannitol NN cord-006870-f5w6fw6q 5950 10 , , , cord-006870-f5w6fw6q 5950 11 23.4 23.4 CD cord-006870-f5w6fw6q 5950 12 % % NN cord-006870-f5w6fw6q 5950 13 hypertonic hypertonic JJ cord-006870-f5w6fw6q 5950 14 saline saline NN cord-006870-f5w6fw6q 5950 15 followed follow VBN cord-006870-f5w6fw6q 5950 16 by by IN cord-006870-f5w6fw6q 5950 17 an an DT cord-006870-f5w6fw6q 5950 18 infusion infusion NN cord-006870-f5w6fw6q 5950 19 of of IN cord-006870-f5w6fw6q 5950 20 3 3 CD cord-006870-f5w6fw6q 5950 21 % % NN cord-006870-f5w6fw6q 5950 22 hypertonic hypertonic JJ cord-006870-f5w6fw6q 5950 23 saline saline NN cord-006870-f5w6fw6q 5950 24 infusion infusion NN cord-006870-f5w6fw6q 5950 25 . . . cord-006870-f5w6fw6q 5951 1 Serial serial JJ cord-006870-f5w6fw6q 5951 2 CTs ct NNS cord-006870-f5w6fw6q 5951 3 revealed reveal VBD cord-006870-f5w6fw6q 5951 4 complete complete JJ cord-006870-f5w6fw6q 5951 5 resolution resolution NN cord-006870-f5w6fw6q 5951 6 of of IN cord-006870-f5w6fw6q 5951 7 his -PRON- PRP$ cord-006870-f5w6fw6q 5951 8 cerebral cerebral JJ cord-006870-f5w6fw6q 5951 9 edema edema NN cord-006870-f5w6fw6q 5951 10 48 48 CD cord-006870-f5w6fw6q 5951 11 hours hour NNS cord-006870-f5w6fw6q 5951 12 after after IN cord-006870-f5w6fw6q 5951 13 admission admission NN cord-006870-f5w6fw6q 5951 14 ( ( -LRB- cord-006870-f5w6fw6q 5951 15 fig fig NN cord-006870-f5w6fw6q 5951 16 . . NNP cord-006870-f5w6fw6q 5951 17 2 2 CD cord-006870-f5w6fw6q 5951 18 and and CC cord-006870-f5w6fw6q 5951 19 3 3 CD cord-006870-f5w6fw6q 5951 20 ) ) -RRB- cord-006870-f5w6fw6q 5951 21 . . . cord-006870-f5w6fw6q 5952 1 The the DT cord-006870-f5w6fw6q 5952 2 patient patient NN cord-006870-f5w6fw6q 5952 3 's 's POS cord-006870-f5w6fw6q 5952 4 mental mental JJ cord-006870-f5w6fw6q 5952 5 status status NN cord-006870-f5w6fw6q 5952 6 improved improve VBN cord-006870-f5w6fw6q 5952 7 , , , cord-006870-f5w6fw6q 5952 8 was be VBD cord-006870-f5w6fw6q 5952 9 extubated extubate VBN cord-006870-f5w6fw6q 5952 10 , , , cord-006870-f5w6fw6q 5952 11 and and CC cord-006870-f5w6fw6q 5952 12 then then RB cord-006870-f5w6fw6q 5952 13 was be VBD cord-006870-f5w6fw6q 5952 14 discharged discharge VBN cord-006870-f5w6fw6q 5952 15 home home NN cord-006870-f5w6fw6q 5952 16 5 5 CD cord-006870-f5w6fw6q 5952 17 days day NNS cord-006870-f5w6fw6q 5952 18 after after IN cord-006870-f5w6fw6q 5952 19 admission admission NN cord-006870-f5w6fw6q 5952 20 . . . cord-006870-f5w6fw6q 5953 1 While while IN cord-006870-f5w6fw6q 5953 2 significant significant JJ cord-006870-f5w6fw6q 5953 3 adverse adverse JJ cord-006870-f5w6fw6q 5953 4 effects effect NNS cord-006870-f5w6fw6q 5953 5 of of IN cord-006870-f5w6fw6q 5953 6 non non JJ cord-006870-f5w6fw6q 5953 7 - - JJ cord-006870-f5w6fw6q 5953 8 ionic ionic JJ cord-006870-f5w6fw6q 5953 9 contrast contrast NN cord-006870-f5w6fw6q 5953 10 following follow VBG cord-006870-f5w6fw6q 5953 11 spinal spinal JJ cord-006870-f5w6fw6q 5953 12 myelography myelography NN cord-006870-f5w6fw6q 5953 13 are be VBP cord-006870-f5w6fw6q 5953 14 rare rare JJ cord-006870-f5w6fw6q 5953 15 , , , cord-006870-f5w6fw6q 5953 16 the the DT cord-006870-f5w6fw6q 5953 17 potential potential JJ cord-006870-f5w6fw6q 5953 18 life life NN cord-006870-f5w6fw6q 5953 19 threatening threaten VBG cord-006870-f5w6fw6q 5953 20 severity severity NN cord-006870-f5w6fw6q 5953 21 of of IN cord-006870-f5w6fw6q 5953 22 these these DT cord-006870-f5w6fw6q 5953 23 incidents incident NNS cord-006870-f5w6fw6q 5953 24 warrants warrant NNS cord-006870-f5w6fw6q 5953 25 further further JJ cord-006870-f5w6fw6q 5953 26 patient patient JJ cord-006870-f5w6fw6q 5953 27 education education NN cord-006870-f5w6fw6q 5953 28 following follow VBG cord-006870-f5w6fw6q 5953 29 this this DT cord-006870-f5w6fw6q 5953 30 routine routine JJ cord-006870-f5w6fw6q 5953 31 outpatient outpatient NN cord-006870-f5w6fw6q 5953 32 procedure procedure NN cord-006870-f5w6fw6q 5953 33 . . . cord-006870-f5w6fw6q 5954 1 We -PRON- PRP cord-006870-f5w6fw6q 5954 2 recommend recommend VBP cord-006870-f5w6fw6q 5954 3 close close JJ cord-006870-f5w6fw6q 5954 4 neurological neurological JJ cord-006870-f5w6fw6q 5954 5 monitoring monitoring NN cord-006870-f5w6fw6q 5954 6 after after IN cord-006870-f5w6fw6q 5954 7 intrathecal intrathecal JJ cord-006870-f5w6fw6q 5954 8 administration administration NN cord-006870-f5w6fw6q 5954 9 of of IN cord-006870-f5w6fw6q 5954 10 contrast contrast NN cord-006870-f5w6fw6q 5954 11 media medium NNS cord-006870-f5w6fw6q 5954 12 . . . cord-006870-f5w6fw6q 5955 1 Patients patient NNS cord-006870-f5w6fw6q 5955 2 should should MD cord-006870-f5w6fw6q 5955 3 be be VB cord-006870-f5w6fw6q 5955 4 provided provide VBN cord-006870-f5w6fw6q 5955 5 with with IN cord-006870-f5w6fw6q 5955 6 detailed detailed JJ cord-006870-f5w6fw6q 5955 7 instructions instruction NNS cord-006870-f5w6fw6q 5955 8 about about IN cord-006870-f5w6fw6q 5955 9 the the DT cord-006870-f5w6fw6q 5955 10 potential potential JJ cord-006870-f5w6fw6q 5955 11 side side NN cord-006870-f5w6fw6q 5955 12 effects effect NNS cord-006870-f5w6fw6q 5955 13 of of IN cord-006870-f5w6fw6q 5955 14 non non JJ cord-006870-f5w6fw6q 5955 15 - - JJ cord-006870-f5w6fw6q 5955 16 ionic ionic JJ cord-006870-f5w6fw6q 5955 17 contrast contrast NN cord-006870-f5w6fw6q 5955 18 and and CC cord-006870-f5w6fw6q 5955 19 how how WRB cord-006870-f5w6fw6q 5955 20 to to TO cord-006870-f5w6fw6q 5955 21 seek seek VB cord-006870-f5w6fw6q 5955 22 medical medical JJ cord-006870-f5w6fw6q 5955 23 attention attention NN cord-006870-f5w6fw6q 5955 24 if if IN cord-006870-f5w6fw6q 5955 25 symptoms symptom NNS cord-006870-f5w6fw6q 5955 26 of of IN cord-006870-f5w6fw6q 5955 27 cerebral cerebral JJ cord-006870-f5w6fw6q 5955 28 edema edema NN cord-006870-f5w6fw6q 5955 29 are be VBP cord-006870-f5w6fw6q 5955 30 noted note VBN cord-006870-f5w6fw6q 5955 31 post post NN cord-006870-f5w6fw6q 5955 32 procedurally procedurally RB cord-006870-f5w6fw6q 5955 33 . . . cord-006870-f5w6fw6q 5956 1 A a DT cord-006870-f5w6fw6q 5956 2 large large JJ cord-006870-f5w6fw6q 5956 3 acute acute JJ cord-006870-f5w6fw6q 5956 4 traumatic traumatic JJ cord-006870-f5w6fw6q 5956 5 subdural subdural JJ cord-006870-f5w6fw6q 5956 6 hematoma hematoma NN cord-006870-f5w6fw6q 5956 7 with with IN cord-006870-f5w6fw6q 5956 8 brain brain NN cord-006870-f5w6fw6q 5956 9 compression compression NN cord-006870-f5w6fw6q 5956 10 and and CC cord-006870-f5w6fw6q 5956 11 midline midline JJ cord-006870-f5w6fw6q 5956 12 shift shift NN cord-006870-f5w6fw6q 5956 13 is be VBZ cord-006870-f5w6fw6q 5956 14 typically typically RB cord-006870-f5w6fw6q 5956 15 considered consider VBN cord-006870-f5w6fw6q 5956 16 a a DT cord-006870-f5w6fw6q 5956 17 neurological neurological JJ cord-006870-f5w6fw6q 5956 18 emergency emergency NN cord-006870-f5w6fw6q 5956 19 necessitation necessitation NN cord-006870-f5w6fw6q 5956 20 surgery surgery NN cord-006870-f5w6fw6q 5956 21 . . . cord-006870-f5w6fw6q 5957 1 Spontaneous spontaneous JJ cord-006870-f5w6fw6q 5957 2 resolution resolution NN cord-006870-f5w6fw6q 5957 3 of of IN cord-006870-f5w6fw6q 5957 4 a a DT cord-006870-f5w6fw6q 5957 5 large large JJ cord-006870-f5w6fw6q 5957 6 subdural subdural JJ cord-006870-f5w6fw6q 5957 7 hematoma hematoma NN cord-006870-f5w6fw6q 5957 8 is be VBZ cord-006870-f5w6fw6q 5957 9 considered consider VBN cord-006870-f5w6fw6q 5957 10 a a DT cord-006870-f5w6fw6q 5957 11 rare rare JJ cord-006870-f5w6fw6q 5957 12 phenomenon phenomenon NN cord-006870-f5w6fw6q 5957 13 with with IN cord-006870-f5w6fw6q 5957 14 a a DT cord-006870-f5w6fw6q 5957 15 few few JJ cord-006870-f5w6fw6q 5957 16 case case NN cord-006870-f5w6fw6q 5957 17 reported report VBN cord-006870-f5w6fw6q 5957 18 in in IN cord-006870-f5w6fw6q 5957 19 the the DT cord-006870-f5w6fw6q 5957 20 literature literature NN cord-006870-f5w6fw6q 5957 21 . . . cord-006870-f5w6fw6q 5958 1 To to IN cord-006870-f5w6fw6q 5958 2 our -PRON- PRP$ cord-006870-f5w6fw6q 5958 3 knowledge knowledge NN cord-006870-f5w6fw6q 5958 4 , , , cord-006870-f5w6fw6q 5958 5 we -PRON- PRP cord-006870-f5w6fw6q 5958 6 present present VBP cord-006870-f5w6fw6q 5958 7 the the DT cord-006870-f5w6fw6q 5958 8 first first JJ cord-006870-f5w6fw6q 5958 9 case case NN cord-006870-f5w6fw6q 5958 10 of of IN cord-006870-f5w6fw6q 5958 11 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5958 12 resolution resolution NN cord-006870-f5w6fw6q 5958 13 of of IN cord-006870-f5w6fw6q 5958 14 a a DT cord-006870-f5w6fw6q 5958 15 traumatic traumatic JJ cord-006870-f5w6fw6q 5958 16 acute acute JJ cord-006870-f5w6fw6q 5958 17 subdural subdural JJ cord-006870-f5w6fw6q 5958 18 hematoma hematoma NN cord-006870-f5w6fw6q 5958 19 with with IN cord-006870-f5w6fw6q 5958 20 brain brain NN cord-006870-f5w6fw6q 5958 21 compression compression NN cord-006870-f5w6fw6q 5958 22 and and CC cord-006870-f5w6fw6q 5958 23 midline midline JJ cord-006870-f5w6fw6q 5958 24 shift shift NN cord-006870-f5w6fw6q 5958 25 on on IN cord-006870-f5w6fw6q 5958 26 dual dual JJ cord-006870-f5w6fw6q 5958 27 antiplatelet antiplatelet NN cord-006870-f5w6fw6q 5958 28 therapy therapy NN cord-006870-f5w6fw6q 5958 29 . . . cord-006870-f5w6fw6q 5959 1 A a DT cord-006870-f5w6fw6q 5959 2 71 71 CD cord-006870-f5w6fw6q 5959 3 year year NN cord-006870-f5w6fw6q 5959 4 - - HYPH cord-006870-f5w6fw6q 5959 5 old old JJ cord-006870-f5w6fw6q 5959 6 patient patient NN cord-006870-f5w6fw6q 5959 7 initially initially RB cord-006870-f5w6fw6q 5959 8 presented present VBN cord-006870-f5w6fw6q 5959 9 after after IN cord-006870-f5w6fw6q 5959 10 being be VBG cord-006870-f5w6fw6q 5959 11 found find VBN cord-006870-f5w6fw6q 5959 12 down down RP cord-006870-f5w6fw6q 5959 13 and and CC cord-006870-f5w6fw6q 5959 14 unresponsive unresponsive JJ cord-006870-f5w6fw6q 5959 15 in in IN cord-006870-f5w6fw6q 5959 16 his -PRON- PRP$ cord-006870-f5w6fw6q 5959 17 home home NN cord-006870-f5w6fw6q 5959 18 . . . cord-006870-f5w6fw6q 5960 1 The the DT cord-006870-f5w6fw6q 5960 2 patient patient NN cord-006870-f5w6fw6q 5960 3 was be VBD cord-006870-f5w6fw6q 5960 4 on on IN cord-006870-f5w6fw6q 5960 5 aspirin aspirin NN cord-006870-f5w6fw6q 5960 6 and and CC cord-006870-f5w6fw6q 5960 7 clopidigrel clopidigrel NN cord-006870-f5w6fw6q 5960 8 . . . cord-006870-f5w6fw6q 5961 1 He -PRON- PRP cord-006870-f5w6fw6q 5961 2 was be VBD cord-006870-f5w6fw6q 5961 3 found find VBN cord-006870-f5w6fw6q 5961 4 to to TO cord-006870-f5w6fw6q 5961 5 have have VB cord-006870-f5w6fw6q 5961 6 altered alter VBN cord-006870-f5w6fw6q 5961 7 mental mental JJ cord-006870-f5w6fw6q 5961 8 status status NN cord-006870-f5w6fw6q 5961 9 , , , cord-006870-f5w6fw6q 5961 10 was be VBD cord-006870-f5w6fw6q 5961 11 n't not RB cord-006870-f5w6fw6q 5961 12 following follow VBG cord-006870-f5w6fw6q 5961 13 commands command NNS cord-006870-f5w6fw6q 5961 14 , , , cord-006870-f5w6fw6q 5961 15 and and CC cord-006870-f5w6fw6q 5961 16 had have VBD cord-006870-f5w6fw6q 5961 17 a a DT cord-006870-f5w6fw6q 5961 18 Glascow Glascow NNP cord-006870-f5w6fw6q 5961 19 Come come VB cord-006870-f5w6fw6q 5961 20 Scale scale NN cord-006870-f5w6fw6q 5961 21 score score NN cord-006870-f5w6fw6q 5961 22 of of IN cord-006870-f5w6fw6q 5961 23 < < NNP cord-006870-f5w6fw6q 5961 24 8 8 CD cord-006870-f5w6fw6q 5961 25 . . . cord-006870-f5w6fw6q 5962 1 The the DT cord-006870-f5w6fw6q 5962 2 patient patient NN cord-006870-f5w6fw6q 5962 3 's 's POS cord-006870-f5w6fw6q 5962 4 initial initial JJ cord-006870-f5w6fw6q 5962 5 head head NN cord-006870-f5w6fw6q 5962 6 CT CT NNP cord-006870-f5w6fw6q 5962 7 revealed reveal VBD cord-006870-f5w6fw6q 5962 8 a a DT cord-006870-f5w6fw6q 5962 9 large large JJ cord-006870-f5w6fw6q 5962 10 left left JJ cord-006870-f5w6fw6q 5962 11 acute acute JJ cord-006870-f5w6fw6q 5962 12 subdural subdural JJ cord-006870-f5w6fw6q 5962 13 hematoma hematoma NN cord-006870-f5w6fw6q 5962 14 ( ( -LRB- cord-006870-f5w6fw6q 5962 15 SDH SDH NNP cord-006870-f5w6fw6q 5962 16 ) ) -RRB- cord-006870-f5w6fw6q 5962 17 measuring measure VBG cord-006870-f5w6fw6q 5962 18 1.8 1.8 CD cord-006870-f5w6fw6q 5962 19 cm cm NNS cord-006870-f5w6fw6q 5962 20 in in IN cord-006870-f5w6fw6q 5962 21 diameter diameter NN cord-006870-f5w6fw6q 5962 22 . . . cord-006870-f5w6fw6q 5963 1 Neurosurgery Neurosurgery NNP cord-006870-f5w6fw6q 5963 2 was be VBD cord-006870-f5w6fw6q 5963 3 consulted consult VBN cord-006870-f5w6fw6q 5963 4 upon upon IN cord-006870-f5w6fw6q 5963 5 arrival arrival NN cord-006870-f5w6fw6q 5963 6 for for IN cord-006870-f5w6fw6q 5963 7 possible possible JJ cord-006870-f5w6fw6q 5963 8 emergent emergent JJ cord-006870-f5w6fw6q 5963 9 evacuation evacuation NN cord-006870-f5w6fw6q 5963 10 . . . cord-006870-f5w6fw6q 5964 1 The the DT cord-006870-f5w6fw6q 5964 2 patient patient NN cord-006870-f5w6fw6q 5964 3 's 's POS cord-006870-f5w6fw6q 5964 4 repeat repeat NN cord-006870-f5w6fw6q 5964 5 head head NN cord-006870-f5w6fw6q 5964 6 CT CT NNP cord-006870-f5w6fw6q 5964 7 showed show VBD cord-006870-f5w6fw6q 5964 8 a a DT cord-006870-f5w6fw6q 5964 9 decreased decrease VBN cord-006870-f5w6fw6q 5964 10 SDH SDH NNP cord-006870-f5w6fw6q 5964 11 to to IN cord-006870-f5w6fw6q 5964 12 1.1 1.1 CD cord-006870-f5w6fw6q 5964 13 cm cm NNS cord-006870-f5w6fw6q 5964 14 in in IN cord-006870-f5w6fw6q 5964 15 diameter diameter NN cord-006870-f5w6fw6q 5964 16 . . . cord-006870-f5w6fw6q 5965 1 Given give VBN cord-006870-f5w6fw6q 5965 2 the the DT cord-006870-f5w6fw6q 5965 3 rapidly rapidly RB cord-006870-f5w6fw6q 5965 4 resolving resolve VBG cord-006870-f5w6fw6q 5965 5 SDH SDH NNP cord-006870-f5w6fw6q 5965 6 , , , cord-006870-f5w6fw6q 5965 7 surgery surgery NN cord-006870-f5w6fw6q 5965 8 was be VBD cord-006870-f5w6fw6q 5965 9 postponed postpone VBN cord-006870-f5w6fw6q 5965 10 . . . cord-006870-f5w6fw6q 5966 1 Another another DT cord-006870-f5w6fw6q 5966 2 repeat repeat NN cord-006870-f5w6fw6q 5966 3 head head NN cord-006870-f5w6fw6q 5966 4 CT CT NNP cord-006870-f5w6fw6q 5966 5 the the DT cord-006870-f5w6fw6q 5966 6 following following JJ cord-006870-f5w6fw6q 5966 7 day day NN cord-006870-f5w6fw6q 5966 8 revealed reveal VBD cord-006870-f5w6fw6q 5966 9 a a DT cord-006870-f5w6fw6q 5966 10 decrease decrease NN cord-006870-f5w6fw6q 5966 11 in in IN cord-006870-f5w6fw6q 5966 12 size size NN cord-006870-f5w6fw6q 5966 13 of of IN cord-006870-f5w6fw6q 5966 14 the the DT cord-006870-f5w6fw6q 5966 15 SDH SDH NNP cord-006870-f5w6fw6q 5966 16 to to IN cord-006870-f5w6fw6q 5966 17 10 10 CD cord-006870-f5w6fw6q 5966 18 mm mm NNS cord-006870-f5w6fw6q 5966 19 in in IN cord-006870-f5w6fw6q 5966 20 diameter diameter NN cord-006870-f5w6fw6q 5966 21 . . . cord-006870-f5w6fw6q 5967 1 Several several JJ cord-006870-f5w6fw6q 5967 2 theories theory NNS cord-006870-f5w6fw6q 5967 3 have have VBP cord-006870-f5w6fw6q 5967 4 been be VBN cord-006870-f5w6fw6q 5967 5 proposed propose VBN cord-006870-f5w6fw6q 5967 6 for for IN cord-006870-f5w6fw6q 5967 7 the the DT cord-006870-f5w6fw6q 5967 8 rapid rapid JJ cord-006870-f5w6fw6q 5967 9 resolution resolution NN cord-006870-f5w6fw6q 5967 10 of of IN cord-006870-f5w6fw6q 5967 11 an an DT cord-006870-f5w6fw6q 5967 12 acute acute JJ cord-006870-f5w6fw6q 5967 13 SDH SDH NNP cord-006870-f5w6fw6q 5967 14 including include VBG cord-006870-f5w6fw6q 5967 15 CSF CSF NNP cord-006870-f5w6fw6q 5967 16 leaking leak VBG cord-006870-f5w6fw6q 5967 17 into into IN cord-006870-f5w6fw6q 5967 18 the the DT cord-006870-f5w6fw6q 5967 19 SDH SDH NNP cord-006870-f5w6fw6q 5967 20 through through IN cord-006870-f5w6fw6q 5967 21 a a DT cord-006870-f5w6fw6q 5967 22 tear tear NN cord-006870-f5w6fw6q 5967 23 in in IN cord-006870-f5w6fw6q 5967 24 the the DT cord-006870-f5w6fw6q 5967 25 arachnoid arachnoid JJ cord-006870-f5w6fw6q 5967 26 membrane membrane NN cord-006870-f5w6fw6q 5967 27 with with IN cord-006870-f5w6fw6q 5967 28 rapid rapid JJ cord-006870-f5w6fw6q 5967 29 reabsorption reabsorption NN cord-006870-f5w6fw6q 5967 30 , , , cord-006870-f5w6fw6q 5967 31 redistribution redistribution NN cord-006870-f5w6fw6q 5967 32 of of IN cord-006870-f5w6fw6q 5967 33 the the DT cord-006870-f5w6fw6q 5967 34 hematoma hematoma NN cord-006870-f5w6fw6q 5967 35 in in IN cord-006870-f5w6fw6q 5967 36 the the DT cord-006870-f5w6fw6q 5967 37 subdural subdural JJ cord-006870-f5w6fw6q 5967 38 space space NN cord-006870-f5w6fw6q 5967 39 , , , cord-006870-f5w6fw6q 5967 40 and and CC cord-006870-f5w6fw6q 5967 41 acute acute JJ cord-006870-f5w6fw6q 5967 42 fluctuations fluctuation NNS cord-006870-f5w6fw6q 5967 43 in in IN cord-006870-f5w6fw6q 5967 44 ICP ICP NNP cord-006870-f5w6fw6q 5967 45 driving drive VBG cord-006870-f5w6fw6q 5967 46 the the DT cord-006870-f5w6fw6q 5967 47 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5967 48 resolution resolution NN cord-006870-f5w6fw6q 5967 49 of of IN cord-006870-f5w6fw6q 5967 50 the the DT cord-006870-f5w6fw6q 5967 51 SDH SDH NNP cord-006870-f5w6fw6q 5967 52 . . . cord-006870-f5w6fw6q 5968 1 Close close JJ cord-006870-f5w6fw6q 5968 2 neurological neurological JJ cord-006870-f5w6fw6q 5968 3 and and CC cord-006870-f5w6fw6q 5968 4 repeat repeat NN cord-006870-f5w6fw6q 5968 5 imaging imaging NN cord-006870-f5w6fw6q 5968 6 may may MD cord-006870-f5w6fw6q 5968 7 be be VB cord-006870-f5w6fw6q 5968 8 helpful helpful JJ cord-006870-f5w6fw6q 5968 9 in in IN cord-006870-f5w6fw6q 5968 10 managing manage VBG cord-006870-f5w6fw6q 5968 11 these these DT cord-006870-f5w6fw6q 5968 12 patients patient NNS cord-006870-f5w6fw6q 5968 13 . . . cord-006870-f5w6fw6q 5969 1 As as IN cord-006870-f5w6fw6q 5969 2 seen see VBN cord-006870-f5w6fw6q 5969 3 in in IN cord-006870-f5w6fw6q 5969 4 our -PRON- PRP$ cord-006870-f5w6fw6q 5969 5 patient patient NN cord-006870-f5w6fw6q 5969 6 and and CC cord-006870-f5w6fw6q 5969 7 others other NNS cord-006870-f5w6fw6q 5969 8 , , , cord-006870-f5w6fw6q 5969 9 a a DT cord-006870-f5w6fw6q 5969 10 low low JJ cord-006870-f5w6fw6q 5969 11 density density NN cord-006870-f5w6fw6q 5969 12 band band NN cord-006870-f5w6fw6q 5969 13 in in IN cord-006870-f5w6fw6q 5969 14 the the DT cord-006870-f5w6fw6q 5969 15 subdural subdural JJ cord-006870-f5w6fw6q 5969 16 hematoma hematoma NN cord-006870-f5w6fw6q 5969 17 may may MD cord-006870-f5w6fw6q 5969 18 indicate indicate VB cord-006870-f5w6fw6q 5969 19 CSF CSF NNP cord-006870-f5w6fw6q 5969 20 and and CC cord-006870-f5w6fw6q 5969 21 be be VB cord-006870-f5w6fw6q 5969 22 a a DT cord-006870-f5w6fw6q 5969 23 predictor predictor NN cord-006870-f5w6fw6q 5969 24 for for IN cord-006870-f5w6fw6q 5969 25 spontaneous spontaneous JJ cord-006870-f5w6fw6q 5969 26 resolution resolution NN cord-006870-f5w6fw6q 5969 27 of of IN cord-006870-f5w6fw6q 5969 28 an an DT cord-006870-f5w6fw6q 5969 29 acute acute JJ cord-006870-f5w6fw6q 5969 30 SDH SDH NNP cord-006870-f5w6fw6q 5969 31 . . . cord-006870-f5w6fw6q 5970 1 The the DT cord-006870-f5w6fw6q 5970 2 features feature NNS cord-006870-f5w6fw6q 5970 3 of of IN cord-006870-f5w6fw6q 5970 4 this this DT cord-006870-f5w6fw6q 5970 5 atypical atypical JJ cord-006870-f5w6fw6q 5970 6 case case NN cord-006870-f5w6fw6q 5970 7 offer offer VBP cord-006870-f5w6fw6q 5970 8 points point NNS cord-006870-f5w6fw6q 5970 9 of of IN cord-006870-f5w6fw6q 5970 10 discussion discussion NN cord-006870-f5w6fw6q 5970 11 regarding regard VBG cord-006870-f5w6fw6q 5970 12 the the DT cord-006870-f5w6fw6q 5970 13 surgical surgical JJ cord-006870-f5w6fw6q 5970 14 or or CC cord-006870-f5w6fw6q 5970 15 non non JJ cord-006870-f5w6fw6q 5970 16 - - JJ cord-006870-f5w6fw6q 5970 17 surgical surgical JJ cord-006870-f5w6fw6q 5970 18 approach approach NN cord-006870-f5w6fw6q 5970 19 of of IN cord-006870-f5w6fw6q 5970 20 these these DT cord-006870-f5w6fw6q 5970 21 patients patient NNS cord-006870-f5w6fw6q 5970 22 . . . cord-006870-f5w6fw6q 5971 1 Early early JJ cord-006870-f5w6fw6q 5971 2 post post JJ cord-006870-f5w6fw6q 5971 3 - - JJ cord-006870-f5w6fw6q 5971 4 hypoxic hypoxic JJ cord-006870-f5w6fw6q 5971 5 myoclonus myoclonus NN cord-006870-f5w6fw6q 5971 6 -or -or HYPH cord-006870-f5w6fw6q 5971 7 myoclonic myoclonic JJ cord-006870-f5w6fw6q 5971 8 status status NN cord-006870-f5w6fw6q 5971 9 epilepticus epilepticus NN cord-006870-f5w6fw6q 5972 1 -develops -develop VBN cord-006870-f5w6fw6q 5973 1 within within IN cord-006870-f5w6fw6q 5973 2 48 48 CD cord-006870-f5w6fw6q 5973 3 hours hour NNS cord-006870-f5w6fw6q 5973 4 of of IN cord-006870-f5w6fw6q 5973 5 the the DT cord-006870-f5w6fw6q 5973 6 initial initial JJ cord-006870-f5w6fw6q 5973 7 anoxic anoxic JJ cord-006870-f5w6fw6q 5973 8 injury injury NN cord-006870-f5w6fw6q 5973 9 and and CC cord-006870-f5w6fw6q 5973 10 is be VBZ cord-006870-f5w6fw6q 5973 11 associated associate VBN cord-006870-f5w6fw6q 5973 12 with with IN cord-006870-f5w6fw6q 5973 13 poor poor JJ cord-006870-f5w6fw6q 5973 14 outcomes outcome NNS cord-006870-f5w6fw6q 5973 15 per per IN cord-006870-f5w6fw6q 5973 16 current current JJ cord-006870-f5w6fw6q 5973 17 AAN AAN NNP cord-006870-f5w6fw6q 5973 18 practice practice NN cord-006870-f5w6fw6q 5973 19 guidelines guideline NNS cord-006870-f5w6fw6q 5973 20 . . . cord-006870-f5w6fw6q 5974 1 Late late JJ cord-006870-f5w6fw6q 5974 2 posthypoxic posthypoxic NNP cord-006870-f5w6fw6q 5975 1 myoclonus myoclonus NNP cord-006870-f5w6fw6q 5975 2 -or -or . cord-006870-f5w6fw6q 5976 1 Lance Lance NNP cord-006870-f5w6fw6q 5976 2 - - HYPH cord-006870-f5w6fw6q 5976 3 Adams Adams NNP cord-006870-f5w6fw6q 5976 4 syndrome syndrome NN cord-006870-f5w6fw6q 5977 1 -develops -develop VBN cord-006870-f5w6fw6q 5978 1 > > NFP cord-006870-f5w6fw6q 5978 2 48 48 CD cord-006870-f5w6fw6q 5978 3 hours hour NNS cord-006870-f5w6fw6q 5978 4 after after IN cord-006870-f5w6fw6q 5978 5 the the DT cord-006870-f5w6fw6q 5978 6 anoxic anoxic JJ cord-006870-f5w6fw6q 5978 7 injury injury NN cord-006870-f5w6fw6q 5978 8 , , , cord-006870-f5w6fw6q 5978 9 consciousness consciousness NN cord-006870-f5w6fw6q 5978 10 is be VBZ cord-006870-f5w6fw6q 5978 11 regained regain VBN cord-006870-f5w6fw6q 5978 12 , , , cord-006870-f5w6fw6q 5978 13 and and CC cord-006870-f5w6fw6q 5978 14 is be VBZ cord-006870-f5w6fw6q 5978 15 associated associate VBN cord-006870-f5w6fw6q 5978 16 with with IN cord-006870-f5w6fw6q 5978 17 relatively relatively RB cord-006870-f5w6fw6q 5978 18 good good JJ cord-006870-f5w6fw6q 5978 19 outcomes outcome NNS cord-006870-f5w6fw6q 5978 20 . . . cord-006870-f5w6fw6q 5979 1 The the DT cord-006870-f5w6fw6q 5979 2 patient patient NN cord-006870-f5w6fw6q 5979 3 is be VBZ cord-006870-f5w6fw6q 5979 4 a a DT cord-006870-f5w6fw6q 5979 5 46 46 CD cord-006870-f5w6fw6q 5979 6 yo yo NNP cord-006870-f5w6fw6q 5979 7 man man NN cord-006870-f5w6fw6q 5979 8 with with IN cord-006870-f5w6fw6q 5979 9 a a DT cord-006870-f5w6fw6q 5979 10 history history NN cord-006870-f5w6fw6q 5979 11 of of IN cord-006870-f5w6fw6q 5979 12 alcohol alcohol NN cord-006870-f5w6fw6q 5979 13 and and CC cord-006870-f5w6fw6q 5979 14 cannabis cannabis NN cord-006870-f5w6fw6q 5979 15 use use VBP cord-006870-f5w6fw6q 5979 16 disorder disorder NN cord-006870-f5w6fw6q 5979 17 , , , cord-006870-f5w6fw6q 5979 18 bipolar bipolar JJ cord-006870-f5w6fw6q 5979 19 disorder disorder NN cord-006870-f5w6fw6q 5979 20 , , , cord-006870-f5w6fw6q 5979 21 PNES PNES NNP cord-006870-f5w6fw6q 5979 22 who who WP cord-006870-f5w6fw6q 5979 23 presented present VBD cord-006870-f5w6fw6q 5979 24 after after IN cord-006870-f5w6fw6q 5979 25 attempted attempt VBN cord-006870-f5w6fw6q 5979 26 hanging hang VBG cord-006870-f5w6fw6q 5979 27 for for IN cord-006870-f5w6fw6q 5979 28 up up IN cord-006870-f5w6fw6q 5979 29 to to TO cord-006870-f5w6fw6q 5979 30 15 15 CD cord-006870-f5w6fw6q 5979 31 minutes minute NNS cord-006870-f5w6fw6q 5979 32 . . . cord-006870-f5w6fw6q 5980 1 Intial intial JJ cord-006870-f5w6fw6q 5980 2 rhythm rhythm NN cord-006870-f5w6fw6q 5980 3 was be VBD cord-006870-f5w6fw6q 5980 4 PEA pea NN cord-006870-f5w6fw6q 5980 5 ; ; : cord-006870-f5w6fw6q 5980 6 he -PRON- PRP cord-006870-f5w6fw6q 5980 7 had have VBD cord-006870-f5w6fw6q 5980 8 3 3 CD cord-006870-f5w6fw6q 5980 9 rounds round NNS cord-006870-f5w6fw6q 5980 10 of of IN cord-006870-f5w6fw6q 5980 11 CPR CPR NNP cord-006870-f5w6fw6q 5980 12 , , , cord-006870-f5w6fw6q 5980 13 received receive VBD cord-006870-f5w6fw6q 5980 14 1 1 CD cord-006870-f5w6fw6q 5980 15 mg mg NNP cord-006870-f5w6fw6q 5980 16 epinephrine epinephrine NN cord-006870-f5w6fw6q 5980 17 , , , cord-006870-f5w6fw6q 5980 18 and and CC cord-006870-f5w6fw6q 5980 19 was be VBD cord-006870-f5w6fw6q 5980 20 intubated intubate VBN cord-006870-f5w6fw6q 5980 21 prior prior RB cord-006870-f5w6fw6q 5980 22 to to IN cord-006870-f5w6fw6q 5980 23 ROSC rosc NN cord-006870-f5w6fw6q 5980 24 . . . cord-006870-f5w6fw6q 5981 1 Myoclonic myoclonic JJ cord-006870-f5w6fw6q 5981 2 jerks jerk NNS cord-006870-f5w6fw6q 5981 3 were be VBD cord-006870-f5w6fw6q 5981 4 noted note VBN cord-006870-f5w6fw6q 5981 5 within within IN cord-006870-f5w6fw6q 5981 6 24 24 CD cord-006870-f5w6fw6q 5981 7 hours hour NNS cord-006870-f5w6fw6q 5981 8 post post NN cord-006870-f5w6fw6q 5981 9 arrest arrest NN cord-006870-f5w6fw6q 5981 10 . . . cord-006870-f5w6fw6q 5982 1 Hypothermia hypothermia NN cord-006870-f5w6fw6q 5982 2 protocol protocol NN cord-006870-f5w6fw6q 5982 3 was be VBD cord-006870-f5w6fw6q 5982 4 initiated initiate VBN cord-006870-f5w6fw6q 5982 5 as as IN cord-006870-f5w6fw6q 5982 6 GCS GCS NNP cord-006870-f5w6fw6q 5982 7 was be VBD cord-006870-f5w6fw6q 5983 1 3T. 3t. CD cord-006870-f5w6fw6q 5983 2 CT CT NNP cord-006870-f5w6fw6q 5983 3 Head Head NNP cord-006870-f5w6fw6q 5983 4 showed show VBD cord-006870-f5w6fw6q 5983 5 subtle subtle JJ cord-006870-f5w6fw6q 5983 6 loss loss NN cord-006870-f5w6fw6q 5983 7 of of IN cord-006870-f5w6fw6q 5983 8 grey grey JJ cord-006870-f5w6fw6q 5983 9 - - HYPH cord-006870-f5w6fw6q 5983 10 white white JJ cord-006870-f5w6fw6q 5983 11 differentiation differentiation NN cord-006870-f5w6fw6q 5983 12 . . . cord-006870-f5w6fw6q 5984 1 EEG EEG NNP cord-006870-f5w6fw6q 5984 2 initially initially RB cord-006870-f5w6fw6q 5984 3 showed show VBD cord-006870-f5w6fw6q 5984 4 that that IN cord-006870-f5w6fw6q 5984 5 his -PRON- PRP$ cord-006870-f5w6fw6q 5984 6 generalized generalized JJ cord-006870-f5w6fw6q 5984 7 myoclonic myoclonic JJ cord-006870-f5w6fw6q 5984 8 jerks jerk NNS cord-006870-f5w6fw6q 5984 9 correlated correlate VBN cord-006870-f5w6fw6q 5984 10 with with IN cord-006870-f5w6fw6q 5984 11 cortical cortical JJ cord-006870-f5w6fw6q 5984 12 activity activity NN cord-006870-f5w6fw6q 5984 13 . . . cord-006870-f5w6fw6q 5985 1 He -PRON- PRP cord-006870-f5w6fw6q 5985 2 was be VBD cord-006870-f5w6fw6q 5985 3 started start VBN cord-006870-f5w6fw6q 5985 4 on on IN cord-006870-f5w6fw6q 5985 5 versed versed JJ cord-006870-f5w6fw6q 5985 6 gtt gtt NN cord-006870-f5w6fw6q 5985 7 , , , cord-006870-f5w6fw6q 5985 8 Keppra Keppra NNP cord-006870-f5w6fw6q 5985 9 , , , cord-006870-f5w6fw6q 5985 10 VPA VPA NNP cord-006870-f5w6fw6q 5985 11 with with IN cord-006870-f5w6fw6q 5985 12 improvement improvement NN cord-006870-f5w6fw6q 5985 13 in in IN cord-006870-f5w6fw6q 5985 14 the the DT cord-006870-f5w6fw6q 5985 15 frequency frequency NN cord-006870-f5w6fw6q 5985 16 of of IN cord-006870-f5w6fw6q 5985 17 jerks jerk NNS cord-006870-f5w6fw6q 5985 18 . . . cord-006870-f5w6fw6q 5986 1 On on IN cord-006870-f5w6fw6q 5986 2 post post JJ cord-006870-f5w6fw6q 5986 3 - - JJ cord-006870-f5w6fw6q 5986 4 arrest arrest JJ cord-006870-f5w6fw6q 5986 5 day day NN cord-006870-f5w6fw6q 5986 6 3 3 CD cord-006870-f5w6fw6q 5986 7 , , , cord-006870-f5w6fw6q 5986 8 MRI MRI NNP cord-006870-f5w6fw6q 5986 9 brain brain NN cord-006870-f5w6fw6q 5986 10 showed show VBD cord-006870-f5w6fw6q 5986 11 mild mild JJ cord-006870-f5w6fw6q 5986 12 cerebellar cerebellar JJ cord-006870-f5w6fw6q 5986 13 edema edema NN cord-006870-f5w6fw6q 5986 14 . . . cord-006870-f5w6fw6q 5987 1 MRI MRI NNP cord-006870-f5w6fw6q 5987 2 C C NNP cord-006870-f5w6fw6q 5987 3 - - HYPH cord-006870-f5w6fw6q 5987 4 spine spine NN cord-006870-f5w6fw6q 5987 5 was be VBD cord-006870-f5w6fw6q 5987 6 negative negative JJ cord-006870-f5w6fw6q 5987 7 for for IN cord-006870-f5w6fw6q 5987 8 significant significant JJ cord-006870-f5w6fw6q 5987 9 myelopathy myelopathy NN cord-006870-f5w6fw6q 5987 10 , , , cord-006870-f5w6fw6q 5987 11 arguing argue VBG cord-006870-f5w6fw6q 5987 12 against against IN cord-006870-f5w6fw6q 5987 13 myoclonus myoclonus NN cord-006870-f5w6fw6q 5987 14 as as IN cord-006870-f5w6fw6q 5987 15 a a DT cord-006870-f5w6fw6q 5987 16 spinal spinal JJ cord-006870-f5w6fw6q 5987 17 reflex reflex NN cord-006870-f5w6fw6q 5987 18 . . . cord-006870-f5w6fw6q 5988 1 Mentation Mentation NNP cord-006870-f5w6fw6q 5988 2 gradually gradually RB cord-006870-f5w6fw6q 5988 3 improved improve VBD cord-006870-f5w6fw6q 5988 4 ; ; : cord-006870-f5w6fw6q 5988 5 on on IN cord-006870-f5w6fw6q 5988 6 post post JJ cord-006870-f5w6fw6q 5988 7 - - JJ cord-006870-f5w6fw6q 5988 8 arrest arrest JJ cord-006870-f5w6fw6q 5988 9 day day NN cord-006870-f5w6fw6q 5988 10 7 7 CD cord-006870-f5w6fw6q 5988 11 he -PRON- PRP cord-006870-f5w6fw6q 5988 12 opened open VBD cord-006870-f5w6fw6q 5988 13 his -PRON- PRP$ cord-006870-f5w6fw6q 5988 14 eyes eye NNS cord-006870-f5w6fw6q 5988 15 to to TO cord-006870-f5w6fw6q 5988 16 command command VB cord-006870-f5w6fw6q 5988 17 . . . cord-006870-f5w6fw6q 5989 1 EEG EEG NNP cord-006870-f5w6fw6q 5989 2 evolved evolve VBD cord-006870-f5w6fw6q 5989 3 to to TO cord-006870-f5w6fw6q 5989 4 show show VB cord-006870-f5w6fw6q 5989 5 GPEDs gped NNS cord-006870-f5w6fw6q 5989 6 and and CC cord-006870-f5w6fw6q 5989 7 SIRPIDs sirpid NNS cord-006870-f5w6fw6q 5989 8 and and CC cord-006870-f5w6fw6q 5989 9 OXC OXC NNP cord-006870-f5w6fw6q 5989 10 and and CC cord-006870-f5w6fw6q 5989 11 TPM TPM NNP cord-006870-f5w6fw6q 5989 12 were be VBD cord-006870-f5w6fw6q 5989 13 added add VBN cord-006870-f5w6fw6q 5989 14 . . . cord-006870-f5w6fw6q 5990 1 On on IN cord-006870-f5w6fw6q 5990 2 post post JJ cord-006870-f5w6fw6q 5990 3 - - JJ cord-006870-f5w6fw6q 5990 4 arrest arrest JJ cord-006870-f5w6fw6q 5990 5 day day NN cord-006870-f5w6fw6q 5990 6 11 11 CD cord-006870-f5w6fw6q 5990 7 a a DT cord-006870-f5w6fw6q 5990 8 paralytic paralytic JJ cord-006870-f5w6fw6q 5990 9 challenge challenge NN cord-006870-f5w6fw6q 5990 10 resolved resolve VBD cord-006870-f5w6fw6q 5990 11 electrographic electrographic JJ cord-006870-f5w6fw6q 5990 12 spikes spike NNS cord-006870-f5w6fw6q 5990 13 , , , cord-006870-f5w6fw6q 5990 14 suggesting suggest VBG cord-006870-f5w6fw6q 5990 15 subcortical subcortical JJ cord-006870-f5w6fw6q 5990 16 origin origin NN cord-006870-f5w6fw6q 5990 17 of of IN cord-006870-f5w6fw6q 5990 18 myoclonus myoclonus NNP cord-006870-f5w6fw6q 5990 19 . . . cord-006870-f5w6fw6q 5991 1 He -PRON- PRP cord-006870-f5w6fw6q 5991 2 continued continue VBD cord-006870-f5w6fw6q 5991 3 to to TO cord-006870-f5w6fw6q 5991 4 improve improve VB cord-006870-f5w6fw6q 5991 5 cognitively cognitively RB cord-006870-f5w6fw6q 5991 6 , , , cord-006870-f5w6fw6q 5991 7 but but CC cord-006870-f5w6fw6q 5991 8 despite despite IN cord-006870-f5w6fw6q 5991 9 clonazepam clonazepam NN cord-006870-f5w6fw6q 5991 10 , , , cord-006870-f5w6fw6q 5991 11 VPA VPA NNP cord-006870-f5w6fw6q 5991 12 , , , cord-006870-f5w6fw6q 5991 13 home home NN cord-006870-f5w6fw6q 5991 14 OXC OXC NNP cord-006870-f5w6fw6q 5992 1 he -PRON- PRP cord-006870-f5w6fw6q 5992 2 continues continue VBZ cord-006870-f5w6fw6q 5992 3 to to TO cord-006870-f5w6fw6q 5992 4 have have VB cord-006870-f5w6fw6q 5992 5 severe severe JJ cord-006870-f5w6fw6q 5992 6 intention intention NN cord-006870-f5w6fw6q 5992 7 myoclonus myoclonus NN cord-006870-f5w6fw6q 5992 8 . . . cord-006870-f5w6fw6q 5993 1 Despite despite IN cord-006870-f5w6fw6q 5993 2 the the DT cord-006870-f5w6fw6q 5993 3 presumed presume VBN cord-006870-f5w6fw6q 5993 4 poor poor JJ cord-006870-f5w6fw6q 5993 5 prognosis prognosis NN cord-006870-f5w6fw6q 5993 6 , , , cord-006870-f5w6fw6q 5993 7 the the DT cord-006870-f5w6fw6q 5993 8 patient patient NN cord-006870-f5w6fw6q 5993 9 's 's POS cord-006870-f5w6fw6q 5993 10 family family NN cord-006870-f5w6fw6q 5993 11 pursued pursue VBD cord-006870-f5w6fw6q 5993 12 aggressive aggressive JJ cord-006870-f5w6fw6q 5993 13 measures measure NNS cord-006870-f5w6fw6q 5993 14 and and CC cord-006870-f5w6fw6q 5993 15 his -PRON- PRP$ cord-006870-f5w6fw6q 5993 16 mentation mentation NN cord-006870-f5w6fw6q 5993 17 gradually gradually RB cord-006870-f5w6fw6q 5993 18 improved improve VBN cord-006870-f5w6fw6q 5993 19 . . . cord-006870-f5w6fw6q 5994 1 Early early JJ cord-006870-f5w6fw6q 5994 2 post post JJ cord-006870-f5w6fw6q 5994 3 - - JJ cord-006870-f5w6fw6q 5994 4 hypoxic hypoxic JJ cord-006870-f5w6fw6q 5994 5 myoclonus myoclonus NN cord-006870-f5w6fw6q 5994 6 carries carry VBZ cord-006870-f5w6fw6q 5994 7 a a DT cord-006870-f5w6fw6q 5994 8 poor poor JJ cord-006870-f5w6fw6q 5994 9 prognosis prognosis NN cord-006870-f5w6fw6q 5994 10 , , , cord-006870-f5w6fw6q 5994 11 however however RB cord-006870-f5w6fw6q 5994 12 , , , cord-006870-f5w6fw6q 5994 13 in in IN cord-006870-f5w6fw6q 5994 14 this this DT cord-006870-f5w6fw6q 5994 15 case case NN cord-006870-f5w6fw6q 5994 16 , , , cord-006870-f5w6fw6q 5994 17 the the DT cord-006870-f5w6fw6q 5994 18 patient patient NN cord-006870-f5w6fw6q 5994 19 survived survive VBD cord-006870-f5w6fw6q 5994 20 with with IN cord-006870-f5w6fw6q 5994 21 a a DT cord-006870-f5w6fw6q 5994 22 good good JJ cord-006870-f5w6fw6q 5994 23 cognitive cognitive JJ cord-006870-f5w6fw6q 5994 24 outcome outcome NN cord-006870-f5w6fw6q 5994 25 likely likely RB cord-006870-f5w6fw6q 5994 26 owing owe VBG cord-006870-f5w6fw6q 5994 27 to to IN cord-006870-f5w6fw6q 5994 28 his -PRON- PRP$ cord-006870-f5w6fw6q 5994 29 age age NN cord-006870-f5w6fw6q 5994 30 and and CC cord-006870-f5w6fw6q 5994 31 relatively relatively RB cord-006870-f5w6fw6q 5994 32 few few JJ cord-006870-f5w6fw6q 5994 33 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 5994 34 . . . cord-006870-f5w6fw6q 5995 1 Further further JJ cord-006870-f5w6fw6q 5995 2 studies study NNS cord-006870-f5w6fw6q 5995 3 are be VBP cord-006870-f5w6fw6q 5995 4 needed need VBN cord-006870-f5w6fw6q 5995 5 to to TO cord-006870-f5w6fw6q 5995 6 differentiate differentiate VB cord-006870-f5w6fw6q 5995 7 early early JJ cord-006870-f5w6fw6q 5995 8 - - HYPH cord-006870-f5w6fw6q 5995 9 onset onset NN cord-006870-f5w6fw6q 5995 10 Lance Lance NNP cord-006870-f5w6fw6q 5995 11 - - HYPH cord-006870-f5w6fw6q 5995 12 Adams Adams NNP cord-006870-f5w6fw6q 5995 13 from from IN cord-006870-f5w6fw6q 5995 14 myoclonic myoclonic JJ cord-006870-f5w6fw6q 5995 15 status status NN cord-006870-f5w6fw6q 5995 16 since since IN cord-006870-f5w6fw6q 5995 17 prognosis prognosis NN cord-006870-f5w6fw6q 5995 18 differs differ VBZ cord-006870-f5w6fw6q 5995 19 greatly greatly RB cord-006870-f5w6fw6q 5995 20 . . . cord-006870-f5w6fw6q 5996 1 Posterior posterior JJ cord-006870-f5w6fw6q 5996 2 reversible reversible JJ cord-006870-f5w6fw6q 5996 3 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 5996 4 syndrome syndrome NN cord-006870-f5w6fw6q 5996 5 ( ( -LRB- cord-006870-f5w6fw6q 5996 6 PRES PRES NNP cord-006870-f5w6fw6q 5996 7 ) ) -RRB- cord-006870-f5w6fw6q 5996 8 can can MD cord-006870-f5w6fw6q 5996 9 occur occur VB cord-006870-f5w6fw6q 5996 10 from from IN cord-006870-f5w6fw6q 5996 11 multiple multiple JJ cord-006870-f5w6fw6q 5996 12 etiologies etiology NNS cord-006870-f5w6fw6q 5996 13 and and CC cord-006870-f5w6fw6q 5996 14 often often RB cord-006870-f5w6fw6q 5996 15 presents present VBZ cord-006870-f5w6fw6q 5996 16 with with IN cord-006870-f5w6fw6q 5996 17 rapid rapid JJ cord-006870-f5w6fw6q 5996 18 - - HYPH cord-006870-f5w6fw6q 5996 19 onset onset NN cord-006870-f5w6fw6q 5996 20 headache headache NN cord-006870-f5w6fw6q 5996 21 , , , cord-006870-f5w6fw6q 5996 22 altered alter VBN cord-006870-f5w6fw6q 5996 23 consciousness consciousness NN cord-006870-f5w6fw6q 5996 24 , , , cord-006870-f5w6fw6q 5996 25 seizures seizure NNS cord-006870-f5w6fw6q 5996 26 and/or and/or CC cord-006870-f5w6fw6q 5996 27 visual visual JJ cord-006870-f5w6fw6q 5996 28 disturbances disturbance NNS cord-006870-f5w6fw6q 5996 29 . . . cord-006870-f5w6fw6q 5997 1 Vasogenic Vasogenic NNP cord-006870-f5w6fw6q 5997 2 edema edema NN cord-006870-f5w6fw6q 5997 3 involving involve VBG cord-006870-f5w6fw6q 5997 4 predominantly predominantly RB cord-006870-f5w6fw6q 5997 5 cerebral cerebral JJ cord-006870-f5w6fw6q 5997 6 white white JJ cord-006870-f5w6fw6q 5997 7 matter matter NN cord-006870-f5w6fw6q 5997 8 is be VBZ cord-006870-f5w6fw6q 5997 9 a a DT cord-006870-f5w6fw6q 5997 10 key key JJ cord-006870-f5w6fw6q 5997 11 finding finding NN cord-006870-f5w6fw6q 5997 12 on on IN cord-006870-f5w6fw6q 5997 13 imaging imaging NN cord-006870-f5w6fw6q 5997 14 studies study NNS cord-006870-f5w6fw6q 5997 15 . . . cord-006870-f5w6fw6q 5998 1 Although although IN cord-006870-f5w6fw6q 5998 2 seizures seizure NNS cord-006870-f5w6fw6q 5998 3 are be VBP cord-006870-f5w6fw6q 5998 4 a a DT cord-006870-f5w6fw6q 5998 5 frequent frequent JJ cord-006870-f5w6fw6q 5998 6 presenting present VBG cord-006870-f5w6fw6q 5998 7 symptom symptom NN cord-006870-f5w6fw6q 5998 8 of of IN cord-006870-f5w6fw6q 5998 9 PRES PRES NNP cord-006870-f5w6fw6q 5998 10 , , , cord-006870-f5w6fw6q 5998 11 refractory refractory JJ cord-006870-f5w6fw6q 5998 12 status status NN cord-006870-f5w6fw6q 5998 13 epilepticus epilepticus NN cord-006870-f5w6fw6q 5998 14 ( ( -LRB- cord-006870-f5w6fw6q 5998 15 RSE RSE NNP cord-006870-f5w6fw6q 5998 16 ) ) -RRB- cord-006870-f5w6fw6q 5998 17 requiring require VBG cord-006870-f5w6fw6q 5998 18 multiple multiple JJ cord-006870-f5w6fw6q 5998 19 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 5998 20 medications medication NNS cord-006870-f5w6fw6q 5998 21 is be VBZ cord-006870-f5w6fw6q 5998 22 very very RB cord-006870-f5w6fw6q 5998 23 rare rare JJ cord-006870-f5w6fw6q 5998 24 . . . cord-006870-f5w6fw6q 5999 1 A a DT cord-006870-f5w6fw6q 5999 2 case case NN cord-006870-f5w6fw6q 5999 3 report report NN cord-006870-f5w6fw6q 5999 4 of of IN cord-006870-f5w6fw6q 5999 5 a a DT cord-006870-f5w6fw6q 5999 6 patient patient NN cord-006870-f5w6fw6q 5999 7 presenting present VBG cord-006870-f5w6fw6q 5999 8 with with IN cord-006870-f5w6fw6q 5999 9 PRES PRES NNP cord-006870-f5w6fw6q 5999 10 and and CC cord-006870-f5w6fw6q 5999 11 clinical clinical JJ cord-006870-f5w6fw6q 5999 12 course course NN cord-006870-f5w6fw6q 5999 13 complicated complicate VBN cord-006870-f5w6fw6q 5999 14 with with IN cord-006870-f5w6fw6q 5999 15 RSE rse NN cord-006870-f5w6fw6q 5999 16 necessitating necessitate VBG cord-006870-f5w6fw6q 5999 17 use use NN cord-006870-f5w6fw6q 5999 18 of of IN cord-006870-f5w6fw6q 5999 19 intravenous intravenous JJ cord-006870-f5w6fw6q 5999 20 anesthesia anesthesia NN cord-006870-f5w6fw6q 5999 21 , , , cord-006870-f5w6fw6q 5999 22 ketamine ketamine NN cord-006870-f5w6fw6q 5999 23 , , , cord-006870-f5w6fw6q 5999 24 and and CC cord-006870-f5w6fw6q 5999 25 newly newly RB cord-006870-f5w6fw6q 5999 26 - - HYPH cord-006870-f5w6fw6q 5999 27 available available JJ cord-006870-f5w6fw6q 5999 28 brivaracetam brivaracetam NNS cord-006870-f5w6fw6q 5999 29 . . . cord-006870-f5w6fw6q 6000 1 65-year 65-year JJ cord-006870-f5w6fw6q 6000 2 - - HYPH cord-006870-f5w6fw6q 6000 3 old old JJ cord-006870-f5w6fw6q 6000 4 woman woman NN cord-006870-f5w6fw6q 6000 5 with with IN cord-006870-f5w6fw6q 6000 6 history history NN cord-006870-f5w6fw6q 6000 7 of of IN cord-006870-f5w6fw6q 6000 8 congestive congestive JJ cord-006870-f5w6fw6q 6000 9 heart heart NN cord-006870-f5w6fw6q 6000 10 failure failure NN cord-006870-f5w6fw6q 6000 11 , , , cord-006870-f5w6fw6q 6000 12 chronic chronic JJ cord-006870-f5w6fw6q 6000 13 iron iron NN cord-006870-f5w6fw6q 6000 14 deficiency deficiency NN cord-006870-f5w6fw6q 6000 15 anemia anemia NN cord-006870-f5w6fw6q 6000 16 and and CC cord-006870-f5w6fw6q 6000 17 uncontrolled uncontrolled JJ cord-006870-f5w6fw6q 6000 18 hypertension hypertension NN cord-006870-f5w6fw6q 6000 19 was be VBD cord-006870-f5w6fw6q 6000 20 admitted admit VBN cord-006870-f5w6fw6q 6000 21 for for IN cord-006870-f5w6fw6q 6000 22 severe severe JJ cord-006870-f5w6fw6q 6000 23 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6000 24 and and CC cord-006870-f5w6fw6q 6000 25 convulsive convulsive JJ cord-006870-f5w6fw6q 6000 26 status status NN cord-006870-f5w6fw6q 6000 27 epilepticus epilepticus NN cord-006870-f5w6fw6q 6000 28 ( ( -LRB- cord-006870-f5w6fw6q 6000 29 CSE CSE NNP cord-006870-f5w6fw6q 6000 30 ) ) -RRB- cord-006870-f5w6fw6q 6000 31 for for IN cord-006870-f5w6fw6q 6000 32 longer long JJR cord-006870-f5w6fw6q 6000 33 than than IN cord-006870-f5w6fw6q 6000 34 30 30 CD cord-006870-f5w6fw6q 6000 35 minutes minute NNS cord-006870-f5w6fw6q 6000 36 necessitating necessitate VBG cord-006870-f5w6fw6q 6000 37 propofol propofol NN cord-006870-f5w6fw6q 6000 38 and and CC cord-006870-f5w6fw6q 6000 39 midazolam midazolam NN cord-006870-f5w6fw6q 6000 40 infusions infusion NNS cord-006870-f5w6fw6q 6000 41 . . . cord-006870-f5w6fw6q 6001 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6001 2 admission admission NN cord-006870-f5w6fw6q 6001 3 systolic systolic JJ cord-006870-f5w6fw6q 6001 4 blood blood NN cord-006870-f5w6fw6q 6001 5 pressures pressure NNS cord-006870-f5w6fw6q 6001 6 were be VBD cord-006870-f5w6fw6q 6001 7 in in IN cord-006870-f5w6fw6q 6001 8 the the DT cord-006870-f5w6fw6q 6001 9 280s 280s NNPS cord-006870-f5w6fw6q 6001 10 , , , cord-006870-f5w6fw6q 6001 11 and and CC cord-006870-f5w6fw6q 6001 12 MRI MRI NNP cord-006870-f5w6fw6q 6001 13 brain brain NN cord-006870-f5w6fw6q 6001 14 revealed reveal VBD cord-006870-f5w6fw6q 6001 15 bilateral bilateral JJ cord-006870-f5w6fw6q 6001 16 parieto parieto NN cord-006870-f5w6fw6q 6001 17 - - HYPH cord-006870-f5w6fw6q 6001 18 occipital occipital NNP cord-006870-f5w6fw6q 6001 19 T2 T2 NNP cord-006870-f5w6fw6q 6001 20 / / SYM cord-006870-f5w6fw6q 6001 21 FLAIR FLAIR NNP cord-006870-f5w6fw6q 6001 22 hyperintensities hyperintensitie NNS cord-006870-f5w6fw6q 6001 23 consistent consistent JJ cord-006870-f5w6fw6q 6001 24 with with IN cord-006870-f5w6fw6q 6001 25 PRES PRES NNP cord-006870-f5w6fw6q 6001 26 . . . cord-006870-f5w6fw6q 6002 1 Despite despite IN cord-006870-f5w6fw6q 6002 2 adequate adequate JJ cord-006870-f5w6fw6q 6002 3 control control NN cord-006870-f5w6fw6q 6002 4 of of IN cord-006870-f5w6fw6q 6002 5 hypertension hypertension NN cord-006870-f5w6fw6q 6002 6 following follow VBG cord-006870-f5w6fw6q 6002 7 admission admission NN cord-006870-f5w6fw6q 6002 8 , , , cord-006870-f5w6fw6q 6002 9 patient patient NN cord-006870-f5w6fw6q 6002 10 remained remain VBD cord-006870-f5w6fw6q 6002 11 encephalopathic encephalopathic JJ cord-006870-f5w6fw6q 6002 12 and and CC cord-006870-f5w6fw6q 6002 13 continuous continuous JJ cord-006870-f5w6fw6q 6002 14 electroencephalography electroencephalography NN cord-006870-f5w6fw6q 6002 15 ( ( -LRB- cord-006870-f5w6fw6q 6002 16 EEG EEG NNP cord-006870-f5w6fw6q 6002 17 ) ) -RRB- cord-006870-f5w6fw6q 6002 18 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6002 19 nonconvulsive nonconvulsive JJ cord-006870-f5w6fw6q 6002 20 status status NN cord-006870-f5w6fw6q 6002 21 epilepticus epilepticus NN cord-006870-f5w6fw6q 6002 22 ( ( -LRB- cord-006870-f5w6fw6q 6002 23 NCSE NCSE NNP cord-006870-f5w6fw6q 6002 24 ) ) -RRB- cord-006870-f5w6fw6q 6002 25 . . . cord-006870-f5w6fw6q 6003 1 The the DT cord-006870-f5w6fw6q 6003 2 patient patient NN cord-006870-f5w6fw6q 6003 3 's 's POS cord-006870-f5w6fw6q 6003 4 NCSE NCSE NNP cord-006870-f5w6fw6q 6003 5 continued continue VBD cord-006870-f5w6fw6q 6003 6 despite despite IN cord-006870-f5w6fw6q 6003 7 use use NN cord-006870-f5w6fw6q 6003 8 of of IN cord-006870-f5w6fw6q 6003 9 maintenance maintenance NN cord-006870-f5w6fw6q 6003 10 antiepileptics antiepileptic NNS cord-006870-f5w6fw6q 6003 11 ( ( -LRB- cord-006870-f5w6fw6q 6003 12 fosphenytoin fosphenytoin NNP cord-006870-f5w6fw6q 6003 13 , , , cord-006870-f5w6fw6q 6003 14 lacosamide lacosamide NNP cord-006870-f5w6fw6q 6003 15 , , , cord-006870-f5w6fw6q 6003 16 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 6003 17 ) ) -RRB- cord-006870-f5w6fw6q 6003 18 and and CC cord-006870-f5w6fw6q 6003 19 high high JJ cord-006870-f5w6fw6q 6003 20 - - HYPH cord-006870-f5w6fw6q 6003 21 dose dose NN cord-006870-f5w6fw6q 6003 22 infusions infusion NNS cord-006870-f5w6fw6q 6003 23 of of IN cord-006870-f5w6fw6q 6003 24 midazolam midazolam NN cord-006870-f5w6fw6q 6003 25 and and CC cord-006870-f5w6fw6q 6003 26 propofol propofol NN cord-006870-f5w6fw6q 6003 27 . . . cord-006870-f5w6fw6q 6004 1 Ketamine Ketamine NNP cord-006870-f5w6fw6q 6004 2 infusion infusion NN cord-006870-f5w6fw6q 6004 3 was be VBD cord-006870-f5w6fw6q 6004 4 started start VBN cord-006870-f5w6fw6q 6004 5 to to TO cord-006870-f5w6fw6q 6004 6 maximize maximize VB cord-006870-f5w6fw6q 6004 7 NMDA NMDA NNP cord-006870-f5w6fw6q 6004 8 receptor receptor NN cord-006870-f5w6fw6q 6004 9 blocking block VBG cord-006870-f5w6fw6q 6004 10 properties property NNS cord-006870-f5w6fw6q 6004 11 , , , cord-006870-f5w6fw6q 6004 12 and and CC cord-006870-f5w6fw6q 6004 13 burstsuppression burstsuppression NN cord-006870-f5w6fw6q 6004 14 pattern pattern NN cord-006870-f5w6fw6q 6004 15 on on IN cord-006870-f5w6fw6q 6004 16 EEG EEG NNP cord-006870-f5w6fw6q 6004 17 was be VBD cord-006870-f5w6fw6q 6004 18 easily easily RB cord-006870-f5w6fw6q 6004 19 achieved achieve VBN cord-006870-f5w6fw6q 6004 20 with with IN cord-006870-f5w6fw6q 6004 21 bolus bolus NN cord-006870-f5w6fw6q 6004 22 infusions infusion NNS cord-006870-f5w6fw6q 6004 23 followed follow VBN cord-006870-f5w6fw6q 6004 24 by by IN cord-006870-f5w6fw6q 6004 25 continuous continuous JJ cord-006870-f5w6fw6q 6004 26 infusion infusion NN cord-006870-f5w6fw6q 6004 27 . . . cord-006870-f5w6fw6q 6005 1 Addition addition NN cord-006870-f5w6fw6q 6005 2 of of IN cord-006870-f5w6fw6q 6005 3 brivaracetam brivaracetam NNS cord-006870-f5w6fw6q 6005 4 was be VBD cord-006870-f5w6fw6q 6005 5 used use VBN cord-006870-f5w6fw6q 6005 6 to to TO cord-006870-f5w6fw6q 6005 7 replace replace VB cord-006870-f5w6fw6q 6005 8 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 6005 9 and and CC cord-006870-f5w6fw6q 6005 10 allowed allow VBN cord-006870-f5w6fw6q 6005 11 patient patient JJ cord-006870-f5w6fw6q 6005 12 to to TO cord-006870-f5w6fw6q 6005 13 remain remain VB cord-006870-f5w6fw6q 6005 14 seizure seizure NN cord-006870-f5w6fw6q 6005 15 - - HYPH cord-006870-f5w6fw6q 6005 16 free free JJ cord-006870-f5w6fw6q 6005 17 when when WRB cord-006870-f5w6fw6q 6005 18 IV IV NNP cord-006870-f5w6fw6q 6005 19 anesthetics anesthetic NNS cord-006870-f5w6fw6q 6005 20 were be VBD cord-006870-f5w6fw6q 6005 21 weaned wean VBN cord-006870-f5w6fw6q 6005 22 off off RP cord-006870-f5w6fw6q 6005 23 . . . cord-006870-f5w6fw6q 6006 1 Patient patient NN cord-006870-f5w6fw6q 6006 2 required require VBD cord-006870-f5w6fw6q 6006 3 prolonged prolonged JJ cord-006870-f5w6fw6q 6006 4 hospitalization hospitalization NN cord-006870-f5w6fw6q 6006 5 with with IN cord-006870-f5w6fw6q 6006 6 gastrostomy gastrostomy NN cord-006870-f5w6fw6q 6006 7 tube tube NN cord-006870-f5w6fw6q 6006 8 placement placement NN cord-006870-f5w6fw6q 6006 9 and and CC cord-006870-f5w6fw6q 6006 10 tracheostomy tracheostomy NN cord-006870-f5w6fw6q 6006 11 , , , cord-006870-f5w6fw6q 6006 12 which which WDT cord-006870-f5w6fw6q 6006 13 was be VBD cord-006870-f5w6fw6q 6006 14 later later RB cord-006870-f5w6fw6q 6006 15 decannulated decannulate VBN cord-006870-f5w6fw6q 6006 16 prior prior RB cord-006870-f5w6fw6q 6006 17 to to IN cord-006870-f5w6fw6q 6006 18 patient patient NN cord-006870-f5w6fw6q 6006 19 's 's POS cord-006870-f5w6fw6q 6006 20 discharge discharge NN cord-006870-f5w6fw6q 6006 21 to to TO cord-006870-f5w6fw6q 6006 22 home home NN cord-006870-f5w6fw6q 6006 23 with with IN cord-006870-f5w6fw6q 6006 24 family family NN cord-006870-f5w6fw6q 6006 25 . . . cord-006870-f5w6fw6q 6007 1 High high JJ cord-006870-f5w6fw6q 6007 2 index index NN cord-006870-f5w6fw6q 6007 3 of of IN cord-006870-f5w6fw6q 6007 4 suspicion suspicion NN cord-006870-f5w6fw6q 6007 5 is be VBZ cord-006870-f5w6fw6q 6007 6 necessary necessary JJ cord-006870-f5w6fw6q 6007 7 to to TO cord-006870-f5w6fw6q 6007 8 identify identify VB cord-006870-f5w6fw6q 6007 9 patients patient NNS cord-006870-f5w6fw6q 6007 10 in in IN cord-006870-f5w6fw6q 6007 11 NCSE NCSE NNP cord-006870-f5w6fw6q 6007 12 with with IN cord-006870-f5w6fw6q 6007 13 prolonged prolong VBN cord-006870-f5w6fw6q 6007 14 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6007 15 that that WDT cord-006870-f5w6fw6q 6007 16 have have VBP cord-006870-f5w6fw6q 6007 17 PRES PRES NNP cord-006870-f5w6fw6q 6007 18 . . . cord-006870-f5w6fw6q 6008 1 Early early JJ cord-006870-f5w6fw6q 6008 2 use use NN cord-006870-f5w6fw6q 6008 3 of of IN cord-006870-f5w6fw6q 6008 4 ketamine ketamine NN cord-006870-f5w6fw6q 6008 5 along along IN cord-006870-f5w6fw6q 6008 6 with with IN cord-006870-f5w6fw6q 6008 7 a a DT cord-006870-f5w6fw6q 6008 8 benzodiazepine benzodiazepine NN cord-006870-f5w6fw6q 6008 9 may may MD cord-006870-f5w6fw6q 6008 10 result result VB cord-006870-f5w6fw6q 6008 11 in in IN cord-006870-f5w6fw6q 6008 12 rapid rapid JJ cord-006870-f5w6fw6q 6008 13 achievement achievement NN cord-006870-f5w6fw6q 6008 14 of of IN cord-006870-f5w6fw6q 6008 15 burstsuppression burstsuppression NN cord-006870-f5w6fw6q 6008 16 to to TO cord-006870-f5w6fw6q 6008 17 treat treat VB cord-006870-f5w6fw6q 6008 18 SE SE NNP cord-006870-f5w6fw6q 6008 19 . . . cord-006870-f5w6fw6q 6009 1 Brivaracetam Brivaracetam NNP cord-006870-f5w6fw6q 6009 2 may may MD cord-006870-f5w6fw6q 6009 3 be be VB cord-006870-f5w6fw6q 6009 4 a a DT cord-006870-f5w6fw6q 6009 5 useful useful JJ cord-006870-f5w6fw6q 6009 6 agent agent NN cord-006870-f5w6fw6q 6009 7 to to TO cord-006870-f5w6fw6q 6009 8 treat treat VB cord-006870-f5w6fw6q 6009 9 RSE RSE NNP cord-006870-f5w6fw6q 6009 10 . . . cord-006870-f5w6fw6q 6010 1 Diagnosis diagnosis NN cord-006870-f5w6fw6q 6010 2 of of IN cord-006870-f5w6fw6q 6010 3 Diabetes Diabetes NNP cord-006870-f5w6fw6q 6010 4 Insipidus(DI Insipidus(DI NNP cord-006870-f5w6fw6q 6010 5 ) ) -RRB- cord-006870-f5w6fw6q 6010 6 includes include VBZ cord-006870-f5w6fw6q 6010 7 polyuria polyuria NN cord-006870-f5w6fw6q 6010 8 , , , cord-006870-f5w6fw6q 6010 9 hypernatremia hypernatremia NN cord-006870-f5w6fw6q 6010 10 and and CC cord-006870-f5w6fw6q 6010 11 low low JJ cord-006870-f5w6fw6q 6010 12 urine urine NN cord-006870-f5w6fw6q 6010 13 specific specific JJ cord-006870-f5w6fw6q 6010 14 gravity gravity NN cord-006870-f5w6fw6q 6010 15 . . . cord-006870-f5w6fw6q 6011 1 We -PRON- PRP cord-006870-f5w6fw6q 6011 2 present present VBP cord-006870-f5w6fw6q 6011 3 two two CD cord-006870-f5w6fw6q 6011 4 patients patient NNS cord-006870-f5w6fw6q 6011 5 , , , cord-006870-f5w6fw6q 6011 6 receiving receive VBG cord-006870-f5w6fw6q 6011 7 hyperosmolar hyperosmolar JJ cord-006870-f5w6fw6q 6011 8 therapy therapy NN cord-006870-f5w6fw6q 6011 9 for for IN cord-006870-f5w6fw6q 6011 10 intracranial intracranial JJ cord-006870-f5w6fw6q 6011 11 hypertension hypertension NN cord-006870-f5w6fw6q 6011 12 ( ( -LRB- cord-006870-f5w6fw6q 6011 13 IHT IHT NNP cord-006870-f5w6fw6q 6011 14 ) ) -RRB- cord-006870-f5w6fw6q 6011 15 , , , cord-006870-f5w6fw6q 6011 16 in in IN cord-006870-f5w6fw6q 6011 17 whom whom WP cord-006870-f5w6fw6q 6011 18 using use VBG cord-006870-f5w6fw6q 6011 19 low low JJ cord-006870-f5w6fw6q 6011 20 urine urine NN cord-006870-f5w6fw6q 6011 21 specific specific JJ cord-006870-f5w6fw6q 6011 22 gravity gravity NN cord-006870-f5w6fw6q 6011 23 to to TO cord-006870-f5w6fw6q 6011 24 diagnose diagnose VB cord-006870-f5w6fw6q 6011 25 DI DI NNP cord-006870-f5w6fw6q 6011 26 lead lead NN cord-006870-f5w6fw6q 6011 27 to to IN cord-006870-f5w6fw6q 6011 28 delayed delay VBN cord-006870-f5w6fw6q 6011 29 treatment treatment NN cord-006870-f5w6fw6q 6011 30 . . . cord-006870-f5w6fw6q 6012 1 This this DT cord-006870-f5w6fw6q 6012 2 is be VBZ cord-006870-f5w6fw6q 6012 3 a a DT cord-006870-f5w6fw6q 6012 4 retrospective retrospective JJ cord-006870-f5w6fw6q 6012 5 case case NN cord-006870-f5w6fw6q 6012 6 series series NN cord-006870-f5w6fw6q 6012 7 . . . cord-006870-f5w6fw6q 6013 1 Criteria criterion NNS cord-006870-f5w6fw6q 6013 2 used use VBD cord-006870-f5w6fw6q 6013 3 to to TO cord-006870-f5w6fw6q 6013 4 diagnose diagnose VB cord-006870-f5w6fw6q 6013 5 DI DI NNP cord-006870-f5w6fw6q 6013 6 at at IN cord-006870-f5w6fw6q 6013 7 our -PRON- PRP$ cord-006870-f5w6fw6q 6013 8 institution institution NN cord-006870-f5w6fw6q 6013 9 include include VBP cord-006870-f5w6fw6q 6013 10 polyuria polyuria NN cord-006870-f5w6fw6q 6013 11 , , , cord-006870-f5w6fw6q 6013 12 sodium sodium NN cord-006870-f5w6fw6q 6013 13 < < XX cord-006870-f5w6fw6q 6013 14 300mOsm 300mOsm NNP cord-006870-f5w6fw6q 6013 15 / / SYM cord-006870-f5w6fw6q 6013 16 kg kg NN cord-006870-f5w6fw6q 6013 17 and and CC cord-006870-f5w6fw6q 6013 18 urine urine NN cord-006870-f5w6fw6q 6013 19 to to IN cord-006870-f5w6fw6q 6013 20 plasma plasma NN cord-006870-f5w6fw6q 6013 21 osmolality osmolality NN cord-006870-f5w6fw6q 6013 22 ratio ratio NN cord-006870-f5w6fw6q 6013 23 < < XX cord-006870-f5w6fw6q 6013 24 2 2 CD cord-006870-f5w6fw6q 6013 25 . . . cord-006870-f5w6fw6q 6014 1 Case case NN cord-006870-f5w6fw6q 6014 2 1 1 CD cord-006870-f5w6fw6q 6014 3 : : : cord-006870-f5w6fw6q 6014 4 23-year 23-year JJ cord-006870-f5w6fw6q 6014 5 - - HYPH cord-006870-f5w6fw6q 6014 6 old old JJ cord-006870-f5w6fw6q 6014 7 male male NN cord-006870-f5w6fw6q 6014 8 with with IN cord-006870-f5w6fw6q 6014 9 subdural subdural JJ cord-006870-f5w6fw6q 6014 10 hematoma hematoma NN cord-006870-f5w6fw6q 6014 11 , , , cord-006870-f5w6fw6q 6014 12 IHT IHT NNP cord-006870-f5w6fw6q 6014 13 on on IN cord-006870-f5w6fw6q 6014 14 hyperosmolar hyperosmolar NNP cord-006870-f5w6fw6q 6014 15 therapy therapy NN cord-006870-f5w6fw6q 6014 16 , , , cord-006870-f5w6fw6q 6014 17 developed develop VBD cord-006870-f5w6fw6q 6014 18 polyuria polyuria NN cord-006870-f5w6fw6q 6014 19 . . . cord-006870-f5w6fw6q 6015 1 Sodium sodium NN cord-006870-f5w6fw6q 6015 2 rose rise VBD cord-006870-f5w6fw6q 6015 3 from from IN cord-006870-f5w6fw6q 6015 4 141 141 CD cord-006870-f5w6fw6q 6015 5 to to IN cord-006870-f5w6fw6q 6015 6 172mEq 172meq CD cord-006870-f5w6fw6q 6015 7 / / SYM cord-006870-f5w6fw6q 6015 8 L. L. NNP cord-006870-f5w6fw6q 6015 9 Urine Urine NNP cord-006870-f5w6fw6q 6015 10 specific specific JJ cord-006870-f5w6fw6q 6015 11 gravity gravity NN cord-006870-f5w6fw6q 6015 12 was be VBD cord-006870-f5w6fw6q 6015 13 1.020 1.020 CD cord-006870-f5w6fw6q 6015 14 excluding exclude VBG cord-006870-f5w6fw6q 6015 15 DI DI NNP cord-006870-f5w6fw6q 6015 16 . . . cord-006870-f5w6fw6q 6016 1 Eventually eventually RB cord-006870-f5w6fw6q 6016 2 , , , cord-006870-f5w6fw6q 6016 3 sodium sodium NN cord-006870-f5w6fw6q 6016 4 rose rise VBD cord-006870-f5w6fw6q 6016 5 to to IN cord-006870-f5w6fw6q 6016 6 184mEQ/ 184meq/ CD cord-006870-f5w6fw6q 6017 1 L. L. NNP cord-006870-f5w6fw6q 6017 2 Specific specific JJ cord-006870-f5w6fw6q 6017 3 gravity gravity NN cord-006870-f5w6fw6q 6017 4 remained remain VBD cord-006870-f5w6fw6q 6017 5 1.009 1.009 CD cord-006870-f5w6fw6q 6017 6 but but CC cord-006870-f5w6fw6q 6017 7 urine urine NN cord-006870-f5w6fw6q 6017 8 osmolality osmolality NN cord-006870-f5w6fw6q 6017 9 was be VBD cord-006870-f5w6fw6q 6017 10 162mOsm 162mosm CD cord-006870-f5w6fw6q 6017 11 / / SYM cord-006870-f5w6fw6q 6017 12 kg kg NN cord-006870-f5w6fw6q 6017 13 and and CC cord-006870-f5w6fw6q 6017 14 urine urine NN cord-006870-f5w6fw6q 6018 1 /plasma /plasma , cord-006870-f5w6fw6q 6018 2 osmolality osmolality NN cord-006870-f5w6fw6q 6018 3 ratio ratio NN cord-006870-f5w6fw6q 6018 4 was be VBD cord-006870-f5w6fw6q 6018 5 0.42 0.42 CD cord-006870-f5w6fw6q 6018 6 , , , cord-006870-f5w6fw6q 6018 7 consistent consistent JJ cord-006870-f5w6fw6q 6018 8 with with IN cord-006870-f5w6fw6q 6018 9 DI DI NNP cord-006870-f5w6fw6q 6018 10 . . . cord-006870-f5w6fw6q 6019 1 Vasopressin Vasopressin NNP cord-006870-f5w6fw6q 6019 2 was be VBD cord-006870-f5w6fw6q 6019 3 initiated initiate VBN cord-006870-f5w6fw6q 6019 4 , , , cord-006870-f5w6fw6q 6019 5 however however RB cord-006870-f5w6fw6q 6019 6 the the DT cord-006870-f5w6fw6q 6019 7 patient patient NN cord-006870-f5w6fw6q 6019 8 had have VBD cord-006870-f5w6fw6q 6019 9 already already RB cord-006870-f5w6fw6q 6019 10 developed develop VBN cord-006870-f5w6fw6q 6019 11 lactic lactic JJ cord-006870-f5w6fw6q 6019 12 acidosis acidosis NN cord-006870-f5w6fw6q 6019 13 and and CC cord-006870-f5w6fw6q 6019 14 renal renal JJ cord-006870-f5w6fw6q 6019 15 failure failure NN cord-006870-f5w6fw6q 6019 16 due due IN cord-006870-f5w6fw6q 6019 17 to to IN cord-006870-f5w6fw6q 6019 18 hypovolemia hypovolemia NN cord-006870-f5w6fw6q 6019 19 . . . cord-006870-f5w6fw6q 6020 1 Case case NN cord-006870-f5w6fw6q 6020 2 2 2 CD cord-006870-f5w6fw6q 6020 3 : : : cord-006870-f5w6fw6q 6020 4 49-year 49-year JJ cord-006870-f5w6fw6q 6020 5 - - HYPH cord-006870-f5w6fw6q 6020 6 old old JJ cord-006870-f5w6fw6q 6020 7 female female NN cord-006870-f5w6fw6q 6020 8 with with IN cord-006870-f5w6fw6q 6020 9 intracerebral intracerebral JJ cord-006870-f5w6fw6q 6020 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6020 11 and and CC cord-006870-f5w6fw6q 6020 12 IHT IHT NNP cord-006870-f5w6fw6q 6020 13 on on IN cord-006870-f5w6fw6q 6020 14 hyperosmolar hyperosmolar NNP cord-006870-f5w6fw6q 6020 15 therapy therapy NN cord-006870-f5w6fw6q 6020 16 , , , cord-006870-f5w6fw6q 6020 17 developed develop VBD cord-006870-f5w6fw6q 6020 18 polyuria polyuria NN cord-006870-f5w6fw6q 6020 19 . . . cord-006870-f5w6fw6q 6021 1 Sodium sodium NN cord-006870-f5w6fw6q 6021 2 rose rise VBD cord-006870-f5w6fw6q 6021 3 to to IN cord-006870-f5w6fw6q 6021 4 176mEq 176meq CD cord-006870-f5w6fw6q 6021 5 / / SYM cord-006870-f5w6fw6q 6021 6 L l NN cord-006870-f5w6fw6q 6021 7 , , , cord-006870-f5w6fw6q 6021 8 specific specific JJ cord-006870-f5w6fw6q 6021 9 gravity gravity NN cord-006870-f5w6fw6q 6021 10 remained remain VBD cord-006870-f5w6fw6q 6021 11 > > XX cord-006870-f5w6fw6q 6021 12 1.005 1.005 CD cord-006870-f5w6fw6q 6021 13 but but CC cord-006870-f5w6fw6q 6021 14 urine urine NN cord-006870-f5w6fw6q 6021 15 osmolality osmolality NN cord-006870-f5w6fw6q 6021 16 was be VBD cord-006870-f5w6fw6q 6021 17 187mOsm 187mosm CD cord-006870-f5w6fw6q 6021 18 / / SYM cord-006870-f5w6fw6q 6021 19 kg kg NN cord-006870-f5w6fw6q 6021 20 and and CC cord-006870-f5w6fw6q 6021 21 urine urine NN cord-006870-f5w6fw6q 6022 1 /plasma /plasma , cord-006870-f5w6fw6q 6022 2 osmolality osmolality NN cord-006870-f5w6fw6q 6022 3 ratio ratio NN cord-006870-f5w6fw6q 6022 4 was be VBD cord-006870-f5w6fw6q 6022 5 0.49 0.49 CD cord-006870-f5w6fw6q 6022 6 consistent consistent JJ cord-006870-f5w6fw6q 6022 7 with with IN cord-006870-f5w6fw6q 6022 8 DI DI NNP cord-006870-f5w6fw6q 6022 9 . . . cord-006870-f5w6fw6q 6023 1 Vasopressin Vasopressin NNP cord-006870-f5w6fw6q 6023 2 was be VBD cord-006870-f5w6fw6q 6023 3 initiated initiate VBN cord-006870-f5w6fw6q 6023 4 . . . cord-006870-f5w6fw6q 6024 1 Hyperosmolar Hyperosmolar NNP cord-006870-f5w6fw6q 6024 2 therapy therapy NN cord-006870-f5w6fw6q 6024 3 increases increase VBZ cord-006870-f5w6fw6q 6024 4 urine urine NN cord-006870-f5w6fw6q 6024 5 osmoles osmole NNS cord-006870-f5w6fw6q 6024 6 and and CC cord-006870-f5w6fw6q 6024 7 raises raise VBZ cord-006870-f5w6fw6q 6024 8 urine urine NN cord-006870-f5w6fw6q 6024 9 specific specific JJ cord-006870-f5w6fw6q 6024 10 gravity gravity NN cord-006870-f5w6fw6q 6024 11 . . . cord-006870-f5w6fw6q 6025 1 This this DT cord-006870-f5w6fw6q 6025 2 interferes interfere VBZ cord-006870-f5w6fw6q 6025 3 with with IN cord-006870-f5w6fw6q 6025 4 diagnosis diagnosis NN cord-006870-f5w6fw6q 6025 5 of of IN cord-006870-f5w6fw6q 6025 6 DI DI NNP cord-006870-f5w6fw6q 6025 7 which which WDT cord-006870-f5w6fw6q 6025 8 requires require VBZ cord-006870-f5w6fw6q 6025 9 low low JJ cord-006870-f5w6fw6q 6025 10 urine urine NN cord-006870-f5w6fw6q 6025 11 specific specific JJ cord-006870-f5w6fw6q 6025 12 gravity gravity NN cord-006870-f5w6fw6q 6025 13 . . . cord-006870-f5w6fw6q 6026 1 While while IN cord-006870-f5w6fw6q 6026 2 specific specific JJ cord-006870-f5w6fw6q 6026 3 gravity gravity NN cord-006870-f5w6fw6q 6026 4 measures measure VBZ cord-006870-f5w6fw6q 6026 5 the the DT cord-006870-f5w6fw6q 6026 6 weight weight NN cord-006870-f5w6fw6q 6026 7 of of IN cord-006870-f5w6fw6q 6026 8 particles particle NNS cord-006870-f5w6fw6q 6026 9 , , , cord-006870-f5w6fw6q 6026 10 osmolality osmolality NN cord-006870-f5w6fw6q 6026 11 measures measure NNS cord-006870-f5w6fw6q 6026 12 particles particle NNS cord-006870-f5w6fw6q 6026 13 independent independent JJ cord-006870-f5w6fw6q 6026 14 of of IN cord-006870-f5w6fw6q 6026 15 their -PRON- PRP$ cord-006870-f5w6fw6q 6026 16 weight weight NN cord-006870-f5w6fw6q 6026 17 and and CC cord-006870-f5w6fw6q 6026 18 thus thus RB cord-006870-f5w6fw6q 6026 19 accurately accurately RB cord-006870-f5w6fw6q 6026 20 measures measure VBZ cord-006870-f5w6fw6q 6026 21 urine urine NN cord-006870-f5w6fw6q 6026 22 tonicity tonicity NN cord-006870-f5w6fw6q 6026 23 in in IN cord-006870-f5w6fw6q 6026 24 the the DT cord-006870-f5w6fw6q 6026 25 presence presence NN cord-006870-f5w6fw6q 6026 26 of of IN cord-006870-f5w6fw6q 6026 27 heavy heavy JJ cord-006870-f5w6fw6q 6026 28 particles particle NNS cord-006870-f5w6fw6q 6026 29 like like IN cord-006870-f5w6fw6q 6026 30 mannitol mannitol NN cord-006870-f5w6fw6q 6026 31 . . . cord-006870-f5w6fw6q 6027 1 Moreover moreover RB cord-006870-f5w6fw6q 6027 2 , , , cord-006870-f5w6fw6q 6027 3 urine urine NN cord-006870-f5w6fw6q 6027 4 / / SYM cord-006870-f5w6fw6q 6027 5 plasma plasma NN cord-006870-f5w6fw6q 6027 6 osmolality osmolality NN cord-006870-f5w6fw6q 6027 7 ratio ratio NN cord-006870-f5w6fw6q 6027 8 is be VBZ cord-006870-f5w6fw6q 6027 9 able able JJ cord-006870-f5w6fw6q 6027 10 to to TO cord-006870-f5w6fw6q 6027 11 demonstrate demonstrate VB cord-006870-f5w6fw6q 6027 12 relative relative JJ cord-006870-f5w6fw6q 6027 13 hyposmolarity hyposmolarity NN cord-006870-f5w6fw6q 6027 14 of of IN cord-006870-f5w6fw6q 6027 15 urine urine NN cord-006870-f5w6fw6q 6027 16 when when WRB cord-006870-f5w6fw6q 6027 17 compared compare VBN cord-006870-f5w6fw6q 6027 18 to to IN cord-006870-f5w6fw6q 6027 19 serum serum NN cord-006870-f5w6fw6q 6027 20 assisting assist VBG cord-006870-f5w6fw6q 6027 21 with with IN cord-006870-f5w6fw6q 6027 22 diagnosis diagnosis NN cord-006870-f5w6fw6q 6027 23 of of IN cord-006870-f5w6fw6q 6027 24 DI DI NNP cord-006870-f5w6fw6q 6027 25 even even RB cord-006870-f5w6fw6q 6027 26 when when WRB cord-006870-f5w6fw6q 6027 27 urine urine NN cord-006870-f5w6fw6q 6027 28 specific specific JJ cord-006870-f5w6fw6q 6027 29 gravity gravity NN cord-006870-f5w6fw6q 6027 30 is be VBZ cord-006870-f5w6fw6q 6027 31 elevated elevate VBN cord-006870-f5w6fw6q 6027 32 . . . cord-006870-f5w6fw6q 6028 1 We -PRON- PRP cord-006870-f5w6fw6q 6028 2 conclude conclude VBP cord-006870-f5w6fw6q 6028 3 that that IN cord-006870-f5w6fw6q 6028 4 urine urine NN cord-006870-f5w6fw6q 6028 5 specific specific JJ cord-006870-f5w6fw6q 6028 6 gravity gravity NN cord-006870-f5w6fw6q 6028 7 does do VBZ cord-006870-f5w6fw6q 6028 8 not not RB cord-006870-f5w6fw6q 6028 9 reliably reliably RB cord-006870-f5w6fw6q 6028 10 detect detect VB cord-006870-f5w6fw6q 6028 11 DI DI NNP cord-006870-f5w6fw6q 6028 12 in in IN cord-006870-f5w6fw6q 6028 13 patients patient NNS cord-006870-f5w6fw6q 6028 14 receiving receive VBG cord-006870-f5w6fw6q 6028 15 hyperosmolar hyperosmolar JJ cord-006870-f5w6fw6q 6028 16 therapy therapy NN cord-006870-f5w6fw6q 6028 17 . . . cord-006870-f5w6fw6q 6029 1 Urine urine NN cord-006870-f5w6fw6q 6029 2 osmolality osmolality NN cord-006870-f5w6fw6q 6029 3 and and CC cord-006870-f5w6fw6q 6029 4 urine urine NN cord-006870-f5w6fw6q 6029 5 / / SYM cord-006870-f5w6fw6q 6029 6 plasma plasma NN cord-006870-f5w6fw6q 6029 7 osmolality osmolality NN cord-006870-f5w6fw6q 6029 8 ratio ratio NN cord-006870-f5w6fw6q 6029 9 may may MD cord-006870-f5w6fw6q 6029 10 detect detect VB cord-006870-f5w6fw6q 6029 11 DI DI NNP cord-006870-f5w6fw6q 6029 12 earlier early RBR cord-006870-f5w6fw6q 6029 13 and and CC cord-006870-f5w6fw6q 6029 14 prevent prevent VB cord-006870-f5w6fw6q 6029 15 dehydration dehydration NN cord-006870-f5w6fw6q 6029 16 and and CC cord-006870-f5w6fw6q 6029 17 kidney kidney NN cord-006870-f5w6fw6q 6029 18 injury injury NN cord-006870-f5w6fw6q 6029 19 . . . cord-006870-f5w6fw6q 6030 1 These these DT cord-006870-f5w6fw6q 6030 2 findings finding NNS cord-006870-f5w6fw6q 6030 3 should should MD cord-006870-f5w6fw6q 6030 4 be be VB cord-006870-f5w6fw6q 6030 5 validated validate VBN cord-006870-f5w6fw6q 6030 6 prospectively prospectively RB cord-006870-f5w6fw6q 6030 7 . . . cord-006870-f5w6fw6q 6031 1 Endovascular endovascular JJ cord-006870-f5w6fw6q 6031 2 intervention intervention NN cord-006870-f5w6fw6q 6031 3 in in IN cord-006870-f5w6fw6q 6031 4 the the DT cord-006870-f5w6fw6q 6031 5 treatment treatment NN cord-006870-f5w6fw6q 6031 6 of of IN cord-006870-f5w6fw6q 6031 7 CVT(cerebral cvt(cerebral JJ cord-006870-f5w6fw6q 6031 8 venous venous JJ cord-006870-f5w6fw6q 6031 9 thrombosis thrombosis NNP cord-006870-f5w6fw6q 6031 10 ) ) -RRB- cord-006870-f5w6fw6q 6031 11 is be VBZ cord-006870-f5w6fw6q 6031 12 an an DT cord-006870-f5w6fw6q 6031 13 alternative alternative JJ cord-006870-f5w6fw6q 6031 14 strategy strategy NN cord-006870-f5w6fw6q 6031 15 when when WRB cord-006870-f5w6fw6q 6031 16 cases case NNS cord-006870-f5w6fw6q 6031 17 deteriorate deteriorate VBP cord-006870-f5w6fw6q 6031 18 despite despite IN cord-006870-f5w6fw6q 6031 19 best good JJS cord-006870-f5w6fw6q 6031 20 medical medical JJ cord-006870-f5w6fw6q 6031 21 management management NN cord-006870-f5w6fw6q 6031 22 or or CC cord-006870-f5w6fw6q 6031 23 develop develop VB cord-006870-f5w6fw6q 6031 24 refractory refractory JJ cord-006870-f5w6fw6q 6031 25 intracranialhypertension intracranialhypertension NN cord-006870-f5w6fw6q 6031 26 . . . cord-006870-f5w6fw6q 6032 1 We -PRON- PRP cord-006870-f5w6fw6q 6032 2 present present VBP cord-006870-f5w6fw6q 6032 3 a a DT cord-006870-f5w6fw6q 6032 4 patient patient NN cord-006870-f5w6fw6q 6032 5 with with IN cord-006870-f5w6fw6q 6032 6 CVT CVT NNP cord-006870-f5w6fw6q 6032 7 due due IN cord-006870-f5w6fw6q 6032 8 to to IN cord-006870-f5w6fw6q 6032 9 heparin heparin NN cord-006870-f5w6fw6q 6032 10 - - HYPH cord-006870-f5w6fw6q 6032 11 induced induce VBN cord-006870-f5w6fw6q 6032 12 thrombocytopenia(HIT thrombocytopenia(HIT NNS cord-006870-f5w6fw6q 6032 13 ) ) -RRB- cord-006870-f5w6fw6q 6032 14 , , , cord-006870-f5w6fw6q 6032 15 with with IN cord-006870-f5w6fw6q 6032 16 intraparenchymal intraparenchymal NNP cord-006870-f5w6fw6q 6032 17 hemorrhage(IPH hemorrhage(iph ADD cord-006870-f5w6fw6q 6032 18 ) ) -RRB- cord-006870-f5w6fw6q 6032 19 and and CC cord-006870-f5w6fw6q 6032 20 refractory refractory JJ cord-006870-f5w6fw6q 6032 21 intracranial intracranial JJ cord-006870-f5w6fw6q 6032 22 - - HYPH cord-006870-f5w6fw6q 6032 23 hypertension hypertension NN cord-006870-f5w6fw6q 6032 24 , , , cord-006870-f5w6fw6q 6032 25 who who WP cord-006870-f5w6fw6q 6032 26 was be VBD cord-006870-f5w6fw6q 6032 27 managed manage VBN cord-006870-f5w6fw6q 6032 28 with with IN cord-006870-f5w6fw6q 6032 29 systemic systemic JJ cord-006870-f5w6fw6q 6032 30 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 6032 31 , , , cord-006870-f5w6fw6q 6032 32 continuous continuous JJ cord-006870-f5w6fw6q 6032 33 intra intra JJ cord-006870-f5w6fw6q 6032 34 - - JJ cord-006870-f5w6fw6q 6032 35 sinus sinus JJ cord-006870-f5w6fw6q 6032 36 infusion infusion NN cord-006870-f5w6fw6q 6032 37 of of IN cord-006870-f5w6fw6q 6032 38 rTPA rTPA NNP cord-006870-f5w6fw6q 6032 39 and and CC cord-006870-f5w6fw6q 6032 40 Mechanical Mechanical NNP cord-006870-f5w6fw6q 6032 41 Thrombectomy(MT Thrombectomy(MT NNP cord-006870-f5w6fw6q 6032 42 ) ) -RRB- cord-006870-f5w6fw6q 6032 43 resulting result VBG cord-006870-f5w6fw6q 6032 44 in in IN cord-006870-f5w6fw6q 6032 45 excellent excellent JJ cord-006870-f5w6fw6q 6032 46 outcome outcome NN cord-006870-f5w6fw6q 6032 47 . . . cord-006870-f5w6fw6q 6033 1 Case Case NNP cord-006870-f5w6fw6q 6033 2 Report Report NNP cord-006870-f5w6fw6q 6033 3 : : : cord-006870-f5w6fw6q 6033 4 A a DT cord-006870-f5w6fw6q 6033 5 50-year 50-year JJ cord-006870-f5w6fw6q 6033 6 - - HYPH cord-006870-f5w6fw6q 6033 7 old old JJ cord-006870-f5w6fw6q 6033 8 woman woman NN cord-006870-f5w6fw6q 6033 9 with with IN cord-006870-f5w6fw6q 6033 10 left left JJ cord-006870-f5w6fw6q 6033 11 parafalcine parafalcine NNP cord-006870-f5w6fw6q 6033 12 meningioma meningioma NNP cord-006870-f5w6fw6q 6033 13 s s NNP cord-006870-f5w6fw6q 6033 14 / / SYM cord-006870-f5w6fw6q 6033 15 p p NN cord-006870-f5w6fw6q 6033 16 cyberknife cyberknife NN cord-006870-f5w6fw6q 6033 17 was be VBD cord-006870-f5w6fw6q 6033 18 started start VBN cord-006870-f5w6fw6q 6033 19 on on IN cord-006870-f5w6fw6q 6033 20 subcutaneous subcutaneous JJ cord-006870-f5w6fw6q 6033 21 heparin heparin NN cord-006870-f5w6fw6q 6033 22 for for IN cord-006870-f5w6fw6q 6033 23 radiation radiation NN cord-006870-f5w6fw6q 6033 24 necrosis necrosis NN cord-006870-f5w6fw6q 6033 25 5 5 CD cord-006870-f5w6fw6q 6033 26 days day NNS cord-006870-f5w6fw6q 6033 27 prior prior RB cord-006870-f5w6fw6q 6033 28 to to IN cord-006870-f5w6fw6q 6033 29 admission admission NN cord-006870-f5w6fw6q 6033 30 . . . cord-006870-f5w6fw6q 6034 1 She -PRON- PRP cord-006870-f5w6fw6q 6034 2 presented present VBD cord-006870-f5w6fw6q 6034 3 to to IN cord-006870-f5w6fw6q 6034 4 the the DT cord-006870-f5w6fw6q 6034 5 hospital hospital NN cord-006870-f5w6fw6q 6034 6 with with IN cord-006870-f5w6fw6q 6034 7 new new JJ cord-006870-f5w6fw6q 6034 8 onset onset NN cord-006870-f5w6fw6q 6034 9 headaches headache NNS cord-006870-f5w6fw6q 6034 10 and and CC cord-006870-f5w6fw6q 6034 11 nausea nausea NN cord-006870-f5w6fw6q 6034 12 . . . cord-006870-f5w6fw6q 6035 1 CT CT NNP cord-006870-f5w6fw6q 6035 2 head head NN cord-006870-f5w6fw6q 6035 3 showed show VBD cord-006870-f5w6fw6q 6035 4 increased increase VBN cord-006870-f5w6fw6q 6035 5 edema edema NN cord-006870-f5w6fw6q 6035 6 with with IN cord-006870-f5w6fw6q 6035 7 mid mid JJ cord-006870-f5w6fw6q 6035 8 - - JJ cord-006870-f5w6fw6q 6035 9 line line NN cord-006870-f5w6fw6q 6035 10 shift shift NN cord-006870-f5w6fw6q 6035 11 around around IN cord-006870-f5w6fw6q 6035 12 the the DT cord-006870-f5w6fw6q 6035 13 meningioma meningioma NN cord-006870-f5w6fw6q 6035 14 , , , cord-006870-f5w6fw6q 6035 15 for for IN cord-006870-f5w6fw6q 6035 16 which which WDT cord-006870-f5w6fw6q 6035 17 steroids steroid NNS cord-006870-f5w6fw6q 6035 18 were be VBD cord-006870-f5w6fw6q 6035 19 started start VBN cord-006870-f5w6fw6q 6035 20 . . . cord-006870-f5w6fw6q 6036 1 Within within IN cord-006870-f5w6fw6q 6036 2 2 2 CD cord-006870-f5w6fw6q 6036 3 days day NNS cord-006870-f5w6fw6q 6036 4 her -PRON- PRP$ cord-006870-f5w6fw6q 6036 5 headaches headache NNS cord-006870-f5w6fw6q 6036 6 worsened worsen VBN cord-006870-f5w6fw6q 6036 7 and and CC cord-006870-f5w6fw6q 6036 8 repeat repeat NN cord-006870-f5w6fw6q 6036 9 imaging imaging NN cord-006870-f5w6fw6q 6036 10 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6036 11 right right JJ cord-006870-f5w6fw6q 6036 12 temporal temporal JJ cord-006870-f5w6fw6q 6036 13 IPH iph NN cord-006870-f5w6fw6q 6036 14 . . . cord-006870-f5w6fw6q 6037 1 Emergent emergent JJ cord-006870-f5w6fw6q 6037 2 hematoma hematoma NN cord-006870-f5w6fw6q 6037 3 evacuation evacuation NN cord-006870-f5w6fw6q 6037 4 was be VBD cord-006870-f5w6fw6q 6037 5 performed perform VBN cord-006870-f5w6fw6q 6037 6 . . . cord-006870-f5w6fw6q 6038 1 MRI MRI NNP cord-006870-f5w6fw6q 6038 2 brain brain NN cord-006870-f5w6fw6q 6038 3 showed show VBD cord-006870-f5w6fw6q 6038 4 right right JJ cord-006870-f5w6fw6q 6038 5 cerebellar cerebellar JJ cord-006870-f5w6fw6q 6038 6 infarct infarct NNP cord-006870-f5w6fw6q 6038 7 and and CC cord-006870-f5w6fw6q 6038 8 MRA MRA NNP cord-006870-f5w6fw6q 6038 9 head head NN cord-006870-f5w6fw6q 6038 10 showed show VBD cord-006870-f5w6fw6q 6038 11 extensive extensive JJ cord-006870-f5w6fw6q 6038 12 cavernous cavernous JJ cord-006870-f5w6fw6q 6038 13 sinus sinus NN cord-006870-f5w6fw6q 6038 14 thromboses thrombose NNS cord-006870-f5w6fw6q 6038 15 , , , cord-006870-f5w6fw6q 6038 16 from from IN cord-006870-f5w6fw6q 6038 17 right right JJ cord-006870-f5w6fw6q 6038 18 internal internal JJ cord-006870-f5w6fw6q 6038 19 jugular jugular NN cord-006870-f5w6fw6q 6038 20 vein vein NN cord-006870-f5w6fw6q 6038 21 and and CC cord-006870-f5w6fw6q 6038 22 into into IN cord-006870-f5w6fw6q 6038 23 sigmoid sigmoid JJ cord-006870-f5w6fw6q 6038 24 and and CC cord-006870-f5w6fw6q 6038 25 transverse transverse JJ cord-006870-f5w6fw6q 6038 26 venous venous JJ cord-006870-f5w6fw6q 6038 27 sinuses sinus NNS cord-006870-f5w6fw6q 6038 28 . . . cord-006870-f5w6fw6q 6039 1 She -PRON- PRP cord-006870-f5w6fw6q 6039 2 tested test VBD cord-006870-f5w6fw6q 6039 3 positive positive JJ cord-006870-f5w6fw6q 6039 4 for for IN cord-006870-f5w6fw6q 6039 5 HIT hit NN cord-006870-f5w6fw6q 6039 6 and and CC cord-006870-f5w6fw6q 6039 7 was be VBD cord-006870-f5w6fw6q 6039 8 switched switch VBN cord-006870-f5w6fw6q 6039 9 to to IN cord-006870-f5w6fw6q 6039 10 Argatroban Argatroban NNP cord-006870-f5w6fw6q 6039 11 drip drip NN cord-006870-f5w6fw6q 6039 12 . . . cord-006870-f5w6fw6q 6040 1 Patient patient NN cord-006870-f5w6fw6q 6040 2 however however RB cord-006870-f5w6fw6q 6040 3 continued continue VBD cord-006870-f5w6fw6q 6040 4 to to TO cord-006870-f5w6fw6q 6040 5 deteriorate deteriorate VB cord-006870-f5w6fw6q 6040 6 due due IN cord-006870-f5w6fw6q 6040 7 to to IN cord-006870-f5w6fw6q 6040 8 refractory refractory JJ cord-006870-f5w6fw6q 6040 9 intracranial intracranial JJ cord-006870-f5w6fw6q 6040 10 - - HYPH cord-006870-f5w6fw6q 6040 11 hypertension hypertension NN cord-006870-f5w6fw6q 6040 12 . . . cord-006870-f5w6fw6q 6041 1 Intra intra JJ cord-006870-f5w6fw6q 6041 2 - - JJ cord-006870-f5w6fw6q 6041 3 cavernous cavernous JJ cord-006870-f5w6fw6q 6041 4 rTPA rtpa JJ cord-006870-f5w6fw6q 6041 5 injection injection NN cord-006870-f5w6fw6q 6041 6 and and CC cord-006870-f5w6fw6q 6041 7 MT MT NNP cord-006870-f5w6fw6q 6041 8 was be VBD cord-006870-f5w6fw6q 6041 9 done do VBN cord-006870-f5w6fw6q 6041 10 but but CC cord-006870-f5w6fw6q 6041 11 the the DT cord-006870-f5w6fw6q 6041 12 thrombosis thrombosis NN cord-006870-f5w6fw6q 6041 13 was be VBD cord-006870-f5w6fw6q 6041 14 noted note VBN cord-006870-f5w6fw6q 6041 15 to to TO cord-006870-f5w6fw6q 6041 16 recur recur VB cord-006870-f5w6fw6q 6041 17 on on IN cord-006870-f5w6fw6q 6041 18 repeat repeat NN cord-006870-f5w6fw6q 6042 1 angiogram angiogram NNP cord-006870-f5w6fw6q 6042 2 24hrs 24hrs NNP cord-006870-f5w6fw6q 6042 3 later later RB cord-006870-f5w6fw6q 6042 4 . . . cord-006870-f5w6fw6q 6043 1 An an DT cord-006870-f5w6fw6q 6043 2 intra intra JJ cord-006870-f5w6fw6q 6043 3 - - JJ cord-006870-f5w6fw6q 6043 4 sinus sinus JJ cord-006870-f5w6fw6q 6043 5 catheter catheter NN cord-006870-f5w6fw6q 6043 6 was be VBD cord-006870-f5w6fw6q 6043 7 left leave VBN cord-006870-f5w6fw6q 6043 8 in in IN cord-006870-f5w6fw6q 6043 9 place place NN cord-006870-f5w6fw6q 6043 10 for for IN cord-006870-f5w6fw6q 6043 11 continuous continuous JJ cord-006870-f5w6fw6q 6043 12 infusion infusion NN cord-006870-f5w6fw6q 6043 13 of of IN cord-006870-f5w6fw6q 6043 14 rTPA rtpa XX cord-006870-f5w6fw6q 6043 15 at at IN cord-006870-f5w6fw6q 6043 16 1 1 CD cord-006870-f5w6fw6q 6043 17 mg mg NNP cord-006870-f5w6fw6q 6043 18 / / SYM cord-006870-f5w6fw6q 6043 19 hr hr NN cord-006870-f5w6fw6q 6043 20 . . . cord-006870-f5w6fw6q 6044 1 for for IN cord-006870-f5w6fw6q 6044 2 12hrs 12hrs NNP cord-006870-f5w6fw6q 6044 3 was be VBD cord-006870-f5w6fw6q 6044 4 done do VBN cord-006870-f5w6fw6q 6044 5 while while IN cord-006870-f5w6fw6q 6044 6 Argatroban Argatroban NNP cord-006870-f5w6fw6q 6044 7 drip drip NN cord-006870-f5w6fw6q 6044 8 was be VBD cord-006870-f5w6fw6q 6044 9 continued continue VBN cord-006870-f5w6fw6q 6044 10 . . . cord-006870-f5w6fw6q 6045 1 The the DT cord-006870-f5w6fw6q 6045 2 patient patient NN cord-006870-f5w6fw6q 6045 3 's 's POS cord-006870-f5w6fw6q 6045 4 intracranial intracranial JJ cord-006870-f5w6fw6q 6045 5 pressure pressure NN cord-006870-f5w6fw6q 6045 6 returned return VBN cord-006870-f5w6fw6q 6045 7 to to IN cord-006870-f5w6fw6q 6045 8 normal normal JJ cord-006870-f5w6fw6q 6045 9 . . . cord-006870-f5w6fw6q 6046 1 Repeat repeat NN cord-006870-f5w6fw6q 6046 2 venogram venogram NNP cord-006870-f5w6fw6q 6046 3 showed show VBD cord-006870-f5w6fw6q 6046 4 resolution resolution NN cord-006870-f5w6fw6q 6046 5 of of IN cord-006870-f5w6fw6q 6046 6 CVT CVT NNP cord-006870-f5w6fw6q 6046 7 . . . cord-006870-f5w6fw6q 6047 1 Patient Patient NNP cord-006870-f5w6fw6q 6047 2 tolerated tolerate VBD cord-006870-f5w6fw6q 6047 3 the the DT cord-006870-f5w6fw6q 6047 4 therapies therapy NNS cord-006870-f5w6fw6q 6047 5 well well RB cord-006870-f5w6fw6q 6047 6 , , , cord-006870-f5w6fw6q 6047 7 without without IN cord-006870-f5w6fw6q 6047 8 any any DT cord-006870-f5w6fw6q 6047 9 further further JJ cord-006870-f5w6fw6q 6047 10 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 6047 11 complications complication NNS cord-006870-f5w6fw6q 6047 12 . . . cord-006870-f5w6fw6q 6048 1 Modified modify VBN cord-006870-f5w6fw6q 6048 2 Rankin Rankin NNP cord-006870-f5w6fw6q 6048 3 score score NN cord-006870-f5w6fw6q 6048 4 at at IN cord-006870-f5w6fw6q 6048 5 6 6 CD cord-006870-f5w6fw6q 6048 6 month month NN cord-006870-f5w6fw6q 6048 7 follow follow NN cord-006870-f5w6fw6q 6048 8 - - HYPH cord-006870-f5w6fw6q 6048 9 up up NN cord-006870-f5w6fw6q 6048 10 was be VBD cord-006870-f5w6fw6q 6048 11 1 1 CD cord-006870-f5w6fw6q 6048 12 . . . cord-006870-f5w6fw6q 6049 1 This this DT cord-006870-f5w6fw6q 6049 2 case case NN cord-006870-f5w6fw6q 6049 3 features feature VBZ cord-006870-f5w6fw6q 6049 4 successful successful JJ cord-006870-f5w6fw6q 6049 5 aggressive aggressive JJ cord-006870-f5w6fw6q 6049 6 endovascular endovascular JJ cord-006870-f5w6fw6q 6049 7 interventions intervention NNS cord-006870-f5w6fw6q 6049 8 including include VBG cord-006870-f5w6fw6q 6049 9 in in IN cord-006870-f5w6fw6q 6049 10 - - HYPH cord-006870-f5w6fw6q 6049 11 situ situ JJ cord-006870-f5w6fw6q 6049 12 rTPA rtpa NN cord-006870-f5w6fw6q 6049 13 infusion infusion NN cord-006870-f5w6fw6q 6049 14 , , , cord-006870-f5w6fw6q 6049 15 MT MT NNP cord-006870-f5w6fw6q 6049 16 and and CC cord-006870-f5w6fw6q 6049 17 concomitant concomitant JJ cord-006870-f5w6fw6q 6049 18 systemic systemic JJ cord-006870-f5w6fw6q 6049 19 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 6049 20 for for IN cord-006870-f5w6fw6q 6049 21 CVT cvt NN cord-006870-f5w6fw6q 6049 22 due due JJ cord-006870-f5w6fw6q 6049 23 to to IN cord-006870-f5w6fw6q 6049 24 HIT hit VB cord-006870-f5w6fw6q 6049 25 , , , cord-006870-f5w6fw6q 6049 26 complicated complicate VBN cord-006870-f5w6fw6q 6049 27 by by IN cord-006870-f5w6fw6q 6049 28 intracranial intracranial JJ cord-006870-f5w6fw6q 6049 29 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6049 30 and and CC cord-006870-f5w6fw6q 6049 31 refractory refractory JJ cord-006870-f5w6fw6q 6049 32 intracranial intracranial JJ cord-006870-f5w6fw6q 6049 33 hypertension hypertension NN cord-006870-f5w6fw6q 6049 34 . . . cord-006870-f5w6fw6q 6050 1 The the DT cord-006870-f5w6fw6q 6050 2 paucity paucity NN cord-006870-f5w6fw6q 6050 3 of of IN cord-006870-f5w6fw6q 6050 4 high high JJ cord-006870-f5w6fw6q 6050 5 quality quality NN cord-006870-f5w6fw6q 6050 6 evidence evidence NN cord-006870-f5w6fw6q 6050 7 related relate VBN cord-006870-f5w6fw6q 6050 8 to to IN cord-006870-f5w6fw6q 6050 9 safety safety NN cord-006870-f5w6fw6q 6050 10 , , , cord-006870-f5w6fw6q 6050 11 efficacy efficacy NN cord-006870-f5w6fw6q 6050 12 and and CC cord-006870-f5w6fw6q 6050 13 modality modality NN cord-006870-f5w6fw6q 6050 14 of of IN cord-006870-f5w6fw6q 6050 15 endovascular endovascular JJ cord-006870-f5w6fw6q 6050 16 treatment treatment NN cord-006870-f5w6fw6q 6050 17 lead lead NN cord-006870-f5w6fw6q 6050 18 to to IN cord-006870-f5w6fw6q 6050 19 making make VBG cord-006870-f5w6fw6q 6050 20 therapeutic therapeutic JJ cord-006870-f5w6fw6q 6050 21 decision decision NN cord-006870-f5w6fw6q 6050 22 on on IN cord-006870-f5w6fw6q 6050 23 individual individual JJ cord-006870-f5w6fw6q 6050 24 basis basis NN cord-006870-f5w6fw6q 6050 25 . . . cord-006870-f5w6fw6q 6051 1 Acute acute JJ cord-006870-f5w6fw6q 6051 2 brain brain NN cord-006870-f5w6fw6q 6051 3 injury injury NN cord-006870-f5w6fw6q 6051 4 may may MD cord-006870-f5w6fw6q 6051 5 be be VB cord-006870-f5w6fw6q 6051 6 followed follow VBN cord-006870-f5w6fw6q 6051 7 by by IN cord-006870-f5w6fw6q 6051 8 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6051 9 marked mark VBN cord-006870-f5w6fw6q 6051 10 by by IN cord-006870-f5w6fw6q 6051 11 electroencephalographic electroencephalographic JJ cord-006870-f5w6fw6q 6051 12 features feature NNS cord-006870-f5w6fw6q 6051 13 along along IN cord-006870-f5w6fw6q 6051 14 the the DT cord-006870-f5w6fw6q 6051 15 ictal ictal JJ cord-006870-f5w6fw6q 6051 16 - - HYPH cord-006870-f5w6fw6q 6051 17 interictal interictal JJ cord-006870-f5w6fw6q 6051 18 continuum continuum NN cord-006870-f5w6fw6q 6051 19 ( ( -LRB- cord-006870-f5w6fw6q 6051 20 IIC IIC NNP cord-006870-f5w6fw6q 6051 21 ) ) -RRB- cord-006870-f5w6fw6q 6051 22 . . . cord-006870-f5w6fw6q 6052 1 The the DT cord-006870-f5w6fw6q 6052 2 use use NN cord-006870-f5w6fw6q 6052 3 of of IN cord-006870-f5w6fw6q 6052 4 perfusion perfusion NN cord-006870-f5w6fw6q 6052 5 imaging imaging NN cord-006870-f5w6fw6q 6052 6 to to TO cord-006870-f5w6fw6q 6052 7 co co VB cord-006870-f5w6fw6q 6052 8 - - VB cord-006870-f5w6fw6q 6052 9 localize localize VB cord-006870-f5w6fw6q 6052 10 radiographic radiographic JJ cord-006870-f5w6fw6q 6052 11 features feature NNS cord-006870-f5w6fw6q 6052 12 of of IN cord-006870-f5w6fw6q 6052 13 known know VBN cord-006870-f5w6fw6q 6052 14 malignant malignant JJ cord-006870-f5w6fw6q 6052 15 EEG EEG NNP cord-006870-f5w6fw6q 6052 16 patterns pattern NNS cord-006870-f5w6fw6q 6052 17 may may MD cord-006870-f5w6fw6q 6052 18 add add VB cord-006870-f5w6fw6q 6052 19 an an DT cord-006870-f5w6fw6q 6052 20 important important JJ cord-006870-f5w6fw6q 6052 21 context context NN cord-006870-f5w6fw6q 6052 22 to to TO cord-006870-f5w6fw6q 6052 23 guide guide VB cord-006870-f5w6fw6q 6052 24 treatment treatment NN cord-006870-f5w6fw6q 6052 25 escalation escalation NN cord-006870-f5w6fw6q 6052 26 or or CC cord-006870-f5w6fw6q 6052 27 de de NN cord-006870-f5w6fw6q 6052 28 - - NN cord-006870-f5w6fw6q 6052 29 escalation escalation NN cord-006870-f5w6fw6q 6052 30 . . . cord-006870-f5w6fw6q 6053 1 This this DT cord-006870-f5w6fw6q 6053 2 is be VBZ cord-006870-f5w6fw6q 6053 3 only only RB cord-006870-f5w6fw6q 6053 4 the the DT cord-006870-f5w6fw6q 6053 5 second second JJ cord-006870-f5w6fw6q 6053 6 report report NN cord-006870-f5w6fw6q 6053 7 in in IN cord-006870-f5w6fw6q 6053 8 which which WDT cord-006870-f5w6fw6q 6053 9 widely widely RB cord-006870-f5w6fw6q 6053 10 available available JJ cord-006870-f5w6fw6q 6053 11 CT CT NNP cord-006870-f5w6fw6q 6053 12 or or CC cord-006870-f5w6fw6q 6053 13 MR MR NNP cord-006870-f5w6fw6q 6053 14 perfusion perfusion NN cord-006870-f5w6fw6q 6053 15 techniques technique NNS cord-006870-f5w6fw6q 6053 16 were be VBD cord-006870-f5w6fw6q 6053 17 favored favor VBN cord-006870-f5w6fw6q 6053 18 for for IN cord-006870-f5w6fw6q 6053 19 this this DT cord-006870-f5w6fw6q 6053 20 application application NN cord-006870-f5w6fw6q 6053 21 over over IN cord-006870-f5w6fw6q 6053 22 more more RBR cord-006870-f5w6fw6q 6053 23 cumbersome cumbersome JJ cord-006870-f5w6fw6q 6053 24 metabolic metabolic JJ cord-006870-f5w6fw6q 6053 25 imaging imaging NN cord-006870-f5w6fw6q 6053 26 such such JJ cord-006870-f5w6fw6q 6053 27 as as IN cord-006870-f5w6fw6q 6053 28 PET PET NNP cord-006870-f5w6fw6q 6053 29 . . . cord-006870-f5w6fw6q 6054 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 6054 2 analysis analysis NN cord-006870-f5w6fw6q 6054 3 was be VBD cord-006870-f5w6fw6q 6054 4 performed perform VBN cord-006870-f5w6fw6q 6054 5 on on IN cord-006870-f5w6fw6q 6054 6 records record NNS cord-006870-f5w6fw6q 6054 7 for for IN cord-006870-f5w6fw6q 6054 8 patients patient NNS cord-006870-f5w6fw6q 6054 9 admitted admit VBN cord-006870-f5w6fw6q 6054 10 to to IN cord-006870-f5w6fw6q 6054 11 a a DT cord-006870-f5w6fw6q 6054 12 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 6054 13 ICU ICU NNP cord-006870-f5w6fw6q 6054 14 , , , cord-006870-f5w6fw6q 6054 15 exhibiting exhibit VBG cord-006870-f5w6fw6q 6054 16 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6054 17 , , , cord-006870-f5w6fw6q 6054 18 with with IN cord-006870-f5w6fw6q 6054 19 EEG EEG NNP cord-006870-f5w6fw6q 6054 20 features feature NNS cord-006870-f5w6fw6q 6054 21 on on IN cord-006870-f5w6fw6q 6054 22 the the DT cord-006870-f5w6fw6q 6054 23 IIC IIC NNP cord-006870-f5w6fw6q 6054 24 , , , cord-006870-f5w6fw6q 6054 25 who who WP cord-006870-f5w6fw6q 6054 26 underwent undergo VBD cord-006870-f5w6fw6q 6054 27 perfusion perfusion NN cord-006870-f5w6fw6q 6054 28 imaging imaging NN cord-006870-f5w6fw6q 6054 29 . . . cord-006870-f5w6fw6q 6055 1 Studies study NNS cord-006870-f5w6fw6q 6055 2 included include VBD cord-006870-f5w6fw6q 6055 3 CT CT NNP cord-006870-f5w6fw6q 6055 4 perfusion perfusion NN cord-006870-f5w6fw6q 6055 5 , , , cord-006870-f5w6fw6q 6055 6 MR MR NNP cord-006870-f5w6fw6q 6055 7 perfusion perfusion NN cord-006870-f5w6fw6q 6055 8 , , , cord-006870-f5w6fw6q 6055 9 arterial arterial JJ cord-006870-f5w6fw6q 6055 10 spin spin NN cord-006870-f5w6fw6q 6055 11 labeling labeling NN cord-006870-f5w6fw6q 6055 12 , , , cord-006870-f5w6fw6q 6055 13 or or CC cord-006870-f5w6fw6q 6055 14 SPECT SPECT NNS cord-006870-f5w6fw6q 6055 15 . . . cord-006870-f5w6fw6q 6056 1 These these DT cord-006870-f5w6fw6q 6056 2 studies study NNS cord-006870-f5w6fw6q 6056 3 were be VBD cord-006870-f5w6fw6q 6056 4 obtained obtain VBN cord-006870-f5w6fw6q 6056 5 for for IN cord-006870-f5w6fw6q 6056 6 unrelated unrelated JJ cord-006870-f5w6fw6q 6056 7 purposes purpose NNS cord-006870-f5w6fw6q 6056 8 . . . cord-006870-f5w6fw6q 6057 1 Escalation escalation NN cord-006870-f5w6fw6q 6057 2 or or CC cord-006870-f5w6fw6q 6057 3 de de NN cord-006870-f5w6fw6q 6057 4 - - NN cord-006870-f5w6fw6q 6057 5 escalation escalation NN cord-006870-f5w6fw6q 6057 6 of of IN cord-006870-f5w6fw6q 6057 7 anti anti JJ cord-006870-f5w6fw6q 6057 8 - - JJ cord-006870-f5w6fw6q 6057 9 convulsant convulsant JJ cord-006870-f5w6fw6q 6057 10 and and CC cord-006870-f5w6fw6q 6057 11 sedative sedative JJ cord-006870-f5w6fw6q 6057 12 medication medication NN cord-006870-f5w6fw6q 6057 13 , , , cord-006870-f5w6fw6q 6057 14 hospital hospital NN cord-006870-f5w6fw6q 6057 15 course course NN cord-006870-f5w6fw6q 6057 16 , , , cord-006870-f5w6fw6q 6057 17 and and CC cord-006870-f5w6fw6q 6057 18 patient patient JJ cord-006870-f5w6fw6q 6057 19 outcomes outcome NNS cord-006870-f5w6fw6q 6057 20 were be VBD cord-006870-f5w6fw6q 6057 21 extracted extract VBN cord-006870-f5w6fw6q 6057 22 . . . cord-006870-f5w6fw6q 6058 1 Perfusion perfusion NN cord-006870-f5w6fw6q 6058 2 imaging imaging NN cord-006870-f5w6fw6q 6058 3 data datum NNS cord-006870-f5w6fw6q 6058 4 was be VBD cord-006870-f5w6fw6q 6058 5 juxtaposed juxtapose VBN cord-006870-f5w6fw6q 6058 6 with with IN cord-006870-f5w6fw6q 6058 7 EEG EEG NNP cord-006870-f5w6fw6q 6058 8 patterns pattern NNS cord-006870-f5w6fw6q 6058 9 along along IN cord-006870-f5w6fw6q 6058 10 the the DT cord-006870-f5w6fw6q 6058 11 IIC IIC NNP cord-006870-f5w6fw6q 6058 12 , , , cord-006870-f5w6fw6q 6058 13 and and CC cord-006870-f5w6fw6q 6058 14 patient patient JJ cord-006870-f5w6fw6q 6058 15 outcomes outcome NNS cord-006870-f5w6fw6q 6058 16 are be VBP cord-006870-f5w6fw6q 6058 17 described describe VBN cord-006870-f5w6fw6q 6058 18 in in IN cord-006870-f5w6fw6q 6058 19 narrative narrative NN cord-006870-f5w6fw6q 6058 20 form form NN cord-006870-f5w6fw6q 6058 21 . . . cord-006870-f5w6fw6q 6059 1 Seven seven CD cord-006870-f5w6fw6q 6059 2 cases case NNS cord-006870-f5w6fw6q 6059 3 were be VBD cord-006870-f5w6fw6q 6059 4 identified identify VBN cord-006870-f5w6fw6q 6059 5 . . . cord-006870-f5w6fw6q 6060 1 Four four CD cord-006870-f5w6fw6q 6060 2 cases case NNS cord-006870-f5w6fw6q 6060 3 occurred occur VBD cord-006870-f5w6fw6q 6060 4 in in IN cord-006870-f5w6fw6q 6060 5 the the DT cord-006870-f5w6fw6q 6060 6 context context NN cord-006870-f5w6fw6q 6060 7 of of IN cord-006870-f5w6fw6q 6060 8 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 6060 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6060 10 , , , cord-006870-f5w6fw6q 6060 11 of of IN cord-006870-f5w6fw6q 6060 12 which which WDT cord-006870-f5w6fw6q 6060 13 one one NN cord-006870-f5w6fw6q 6060 14 was be VBD cord-006870-f5w6fw6q 6060 15 secondary secondary JJ cord-006870-f5w6fw6q 6060 16 to to IN cord-006870-f5w6fw6q 6060 17 meningioma meningioma NN cord-006870-f5w6fw6q 6060 18 resection resection NN cord-006870-f5w6fw6q 6060 19 . . . cord-006870-f5w6fw6q 6061 1 Two two CD cord-006870-f5w6fw6q 6061 2 cases case NNS cord-006870-f5w6fw6q 6061 3 occurred occur VBD cord-006870-f5w6fw6q 6061 4 after after IN cord-006870-f5w6fw6q 6061 5 treatment treatment NN cord-006870-f5w6fw6q 6061 6 for for IN cord-006870-f5w6fw6q 6061 7 subdural subdural JJ cord-006870-f5w6fw6q 6061 8 hematoma hematoma NN cord-006870-f5w6fw6q 6061 9 , , , cord-006870-f5w6fw6q 6061 10 and and CC cord-006870-f5w6fw6q 6061 11 one one CD cord-006870-f5w6fw6q 6061 12 case case NN cord-006870-f5w6fw6q 6061 13 was be VBD cord-006870-f5w6fw6q 6061 14 related relate VBN cord-006870-f5w6fw6q 6061 15 to to IN cord-006870-f5w6fw6q 6061 16 ischemic ischemic JJ cord-006870-f5w6fw6q 6061 17 stroke stroke NN cord-006870-f5w6fw6q 6061 18 . . . cord-006870-f5w6fw6q 6062 1 Anti anti JJ cord-006870-f5w6fw6q 6062 2 - - JJ cord-006870-f5w6fw6q 6062 3 convulsant convulsant JJ cord-006870-f5w6fw6q 6062 4 and and CC cord-006870-f5w6fw6q 6062 5 sedative sedative JJ cord-006870-f5w6fw6q 6062 6 management management NN cord-006870-f5w6fw6q 6062 7 was be VBD cord-006870-f5w6fw6q 6062 8 escalated escalate VBN cord-006870-f5w6fw6q 6062 9 or or CC cord-006870-f5w6fw6q 6062 10 de de VBN cord-006870-f5w6fw6q 6062 11 - - VBN cord-006870-f5w6fw6q 6062 12 escalated escalate VBN cord-006870-f5w6fw6q 6062 13 relative relative NN cord-006870-f5w6fw6q 6062 14 to to IN cord-006870-f5w6fw6q 6062 15 the the DT cord-006870-f5w6fw6q 6062 16 presence presence NN cord-006870-f5w6fw6q 6062 17 or or CC cord-006870-f5w6fw6q 6062 18 absence absence NN cord-006870-f5w6fw6q 6062 19 of of IN cord-006870-f5w6fw6q 6062 20 radiographic radiographic JJ cord-006870-f5w6fw6q 6062 21 co co NN cord-006870-f5w6fw6q 6062 22 - - NN cord-006870-f5w6fw6q 6062 23 localization localization NN cord-006870-f5w6fw6q 6062 24 of of IN cord-006870-f5w6fw6q 6062 25 hyperperfusion hyperperfusion NN cord-006870-f5w6fw6q 6062 26 in in IN cord-006870-f5w6fw6q 6062 27 all all DT cord-006870-f5w6fw6q 6062 28 but but IN cord-006870-f5w6fw6q 6062 29 one one CD cord-006870-f5w6fw6q 6062 30 case case NN cord-006870-f5w6fw6q 6062 31 . . . cord-006870-f5w6fw6q 6063 1 Emerging emerge VBG cord-006870-f5w6fw6q 6063 2 data data NN cord-006870-f5w6fw6q 6063 3 indicates indicate VBZ cord-006870-f5w6fw6q 6063 4 that that IN cord-006870-f5w6fw6q 6063 5 some some DT cord-006870-f5w6fw6q 6063 6 IIC IIC NNP cord-006870-f5w6fw6q 6063 7 EEG EEG NNP cord-006870-f5w6fw6q 6063 8 patterns pattern NNS cord-006870-f5w6fw6q 6063 9 may may MD cord-006870-f5w6fw6q 6063 10 merit merit VB cord-006870-f5w6fw6q 6063 11 aggressive aggressive JJ cord-006870-f5w6fw6q 6063 12 treatment treatment NN cord-006870-f5w6fw6q 6063 13 . . . cord-006870-f5w6fw6q 6064 1 Metabolic metabolic JJ cord-006870-f5w6fw6q 6064 2 signatures signature NNS cord-006870-f5w6fw6q 6064 3 of of IN cord-006870-f5w6fw6q 6064 4 secondary secondary JJ cord-006870-f5w6fw6q 6064 5 brain brain NN cord-006870-f5w6fw6q 6064 6 injury injury NN cord-006870-f5w6fw6q 6064 7 as as IN cord-006870-f5w6fw6q 6064 8 measured measure VBN cord-006870-f5w6fw6q 6064 9 by by IN cord-006870-f5w6fw6q 6064 10 cerebro cerebro NNP cord-006870-f5w6fw6q 6064 11 - - HYPH cord-006870-f5w6fw6q 6064 12 oximetry oximetry NN cord-006870-f5w6fw6q 6064 13 or or CC cord-006870-f5w6fw6q 6064 14 microdialysis microdialysis NN cord-006870-f5w6fw6q 6064 15 have have VBP cord-006870-f5w6fw6q 6064 16 associated associate VBN cord-006870-f5w6fw6q 6064 17 these these DT cord-006870-f5w6fw6q 6064 18 patterns pattern NNS cord-006870-f5w6fw6q 6064 19 with with IN cord-006870-f5w6fw6q 6064 20 unfavorable unfavorable JJ cord-006870-f5w6fw6q 6064 21 outcomes outcome NNS cord-006870-f5w6fw6q 6064 22 . . . cord-006870-f5w6fw6q 6065 1 We -PRON- PRP cord-006870-f5w6fw6q 6065 2 report report VBP cord-006870-f5w6fw6q 6065 3 case case NN cord-006870-f5w6fw6q 6065 4 studies study NNS cord-006870-f5w6fw6q 6065 5 in in IN cord-006870-f5w6fw6q 6065 6 which which WDT cord-006870-f5w6fw6q 6065 7 information information NN cord-006870-f5w6fw6q 6065 8 gleaned glean VBN cord-006870-f5w6fw6q 6065 9 from from IN cord-006870-f5w6fw6q 6065 10 basic basic JJ cord-006870-f5w6fw6q 6065 11 perfusion perfusion NN cord-006870-f5w6fw6q 6065 12 imaging imaging NN cord-006870-f5w6fw6q 6065 13 may may MD cord-006870-f5w6fw6q 6065 14 suffice suffice VB cord-006870-f5w6fw6q 6065 15 to to TO cord-006870-f5w6fw6q 6065 16 distinguish distinguish VB cord-006870-f5w6fw6q 6065 17 between between IN cord-006870-f5w6fw6q 6065 18 benign benign JJ cord-006870-f5w6fw6q 6065 19 IIC IIC NNP cord-006870-f5w6fw6q 6065 20 patterns pattern NNS cord-006870-f5w6fw6q 6065 21 and and CC cord-006870-f5w6fw6q 6065 22 those those DT cord-006870-f5w6fw6q 6065 23 that that WDT cord-006870-f5w6fw6q 6065 24 should should MD cord-006870-f5w6fw6q 6065 25 be be VB cord-006870-f5w6fw6q 6065 26 regarded regard VBN cord-006870-f5w6fw6q 6065 27 as as IN cord-006870-f5w6fw6q 6065 28 near near RB cord-006870-f5w6fw6q 6065 29 - - HYPH cord-006870-f5w6fw6q 6065 30 ictal ictal JJ cord-006870-f5w6fw6q 6065 31 . . . cord-006870-f5w6fw6q 6066 1 The the DT cord-006870-f5w6fw6q 6066 2 cases case NNS cord-006870-f5w6fw6q 6066 3 hint hint VBP cord-006870-f5w6fw6q 6066 4 at at IN cord-006870-f5w6fw6q 6066 5 novel novel JJ cord-006870-f5w6fw6q 6066 6 ways way NNS cord-006870-f5w6fw6q 6066 7 to to TO cord-006870-f5w6fw6q 6066 8 conceptualize conceptualize VB cord-006870-f5w6fw6q 6066 9 treatment treatment NN cord-006870-f5w6fw6q 6066 10 of of IN cord-006870-f5w6fw6q 6066 11 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6066 12 following follow VBG cord-006870-f5w6fw6q 6066 13 acute acute JJ cord-006870-f5w6fw6q 6066 14 brain brain NN cord-006870-f5w6fw6q 6066 15 injury injury NN cord-006870-f5w6fw6q 6066 16 and and CC cord-006870-f5w6fw6q 6066 17 suggest suggest VBP cord-006870-f5w6fw6q 6066 18 a a DT cord-006870-f5w6fw6q 6066 19 dimensional dimensional JJ cord-006870-f5w6fw6q 6066 20 shift shift NN cord-006870-f5w6fw6q 6066 21 in in IN cord-006870-f5w6fw6q 6066 22 thinking thinking NN cord-006870-f5w6fw6q 6066 23 towards towards IN cord-006870-f5w6fw6q 6066 24 electroperfusive electroperfusive JJ cord-006870-f5w6fw6q 6066 25 status status NN cord-006870-f5w6fw6q 6066 26 epilepticus epilepticus NN cord-006870-f5w6fw6q 6066 27 . . . cord-006870-f5w6fw6q 6067 1 SUDEP SUDEP NNP cord-006870-f5w6fw6q 6067 2 has have VBZ cord-006870-f5w6fw6q 6067 3 classically classically RB cord-006870-f5w6fw6q 6067 4 been be VBN cord-006870-f5w6fw6q 6067 5 a a DT cord-006870-f5w6fw6q 6067 6 diagnosis diagnosis NN cord-006870-f5w6fw6q 6067 7 of of IN cord-006870-f5w6fw6q 6067 8 exclusion exclusion NN cord-006870-f5w6fw6q 6067 9 . . . cord-006870-f5w6fw6q 6068 1 Recent recent JJ cord-006870-f5w6fw6q 6068 2 studies study NNS cord-006870-f5w6fw6q 6068 3 have have VBP cord-006870-f5w6fw6q 6068 4 shown show VBN cord-006870-f5w6fw6q 6068 5 , , , cord-006870-f5w6fw6q 6068 6 however however RB cord-006870-f5w6fw6q 6068 7 , , , cord-006870-f5w6fw6q 6068 8 that that IN cord-006870-f5w6fw6q 6068 9 similar similar JJ cord-006870-f5w6fw6q 6068 10 genes gene NNS cord-006870-f5w6fw6q 6068 11 -and -and : cord-006870-f5w6fw6q 6068 12 even even RB cord-006870-f5w6fw6q 6068 13 genes gene NNS cord-006870-f5w6fw6q 6068 14 within within IN cord-006870-f5w6fw6q 6068 15 the the DT cord-006870-f5w6fw6q 6068 16 same same JJ cord-006870-f5w6fw6q 6068 17 family family NN cord-006870-f5w6fw6q 6068 18 -are -are : cord-006870-f5w6fw6q 6068 19 associated associate VBN cord-006870-f5w6fw6q 6068 20 with with IN cord-006870-f5w6fw6q 6068 21 SUDEP SUDEP NNP cord-006870-f5w6fw6q 6068 22 and and CC cord-006870-f5w6fw6q 6068 23 Brugada Brugada NNP cord-006870-f5w6fw6q 6068 24 . . . cord-006870-f5w6fw6q 6069 1 This this DT cord-006870-f5w6fw6q 6069 2 suggests suggest VBZ cord-006870-f5w6fw6q 6069 3 that that IN cord-006870-f5w6fw6q 6069 4 perhaps perhaps RB cord-006870-f5w6fw6q 6069 5 the the DT cord-006870-f5w6fw6q 6069 6 cardiac cardiac JJ cord-006870-f5w6fw6q 6069 7 irritability irritability NN cord-006870-f5w6fw6q 6069 8 of of IN cord-006870-f5w6fw6q 6069 9 Brugada Brugada NNP cord-006870-f5w6fw6q 6069 10 Syndrome Syndrome NNP cord-006870-f5w6fw6q 6069 11 exists exist VBZ cord-006870-f5w6fw6q 6069 12 on on IN cord-006870-f5w6fw6q 6069 13 a a DT cord-006870-f5w6fw6q 6069 14 spectrum spectrum NN cord-006870-f5w6fw6q 6069 15 with with IN cord-006870-f5w6fw6q 6069 16 epileptic epileptic JJ cord-006870-f5w6fw6q 6069 17 sudden sudden JJ cord-006870-f5w6fw6q 6069 18 death death NN cord-006870-f5w6fw6q 6069 19 . . . cord-006870-f5w6fw6q 6070 1 A a DT cord-006870-f5w6fw6q 6070 2 25 25 CD cord-006870-f5w6fw6q 6070 3 yo yo NNP cord-006870-f5w6fw6q 6070 4 man man NN cord-006870-f5w6fw6q 6070 5 with with IN cord-006870-f5w6fw6q 6070 6 a a DT cord-006870-f5w6fw6q 6070 7 history history NN cord-006870-f5w6fw6q 6070 8 of of IN cord-006870-f5w6fw6q 6070 9 presumed presume VBN cord-006870-f5w6fw6q 6070 10 seizure seizure NN cord-006870-f5w6fw6q 6070 11 disorder disorder NN cord-006870-f5w6fw6q 6070 12 presented present VBN cord-006870-f5w6fw6q 6070 13 as as IN cord-006870-f5w6fw6q 6070 14 a a DT cord-006870-f5w6fw6q 6070 15 transfer transfer NN cord-006870-f5w6fw6q 6070 16 from from IN cord-006870-f5w6fw6q 6070 17 another another DT cord-006870-f5w6fw6q 6070 18 hospital hospital NN cord-006870-f5w6fw6q 6070 19 after after IN cord-006870-f5w6fw6q 6070 20 being be VBG cord-006870-f5w6fw6q 6070 21 found find VBN cord-006870-f5w6fw6q 6070 22 to to TO cord-006870-f5w6fw6q 6070 23 have have VB cord-006870-f5w6fw6q 6070 24 anoxic anoxic JJ cord-006870-f5w6fw6q 6070 25 brain brain NN cord-006870-f5w6fw6q 6070 26 injury injury NN cord-006870-f5w6fw6q 6070 27 following follow VBG cord-006870-f5w6fw6q 6070 28 cardiac cardiac JJ cord-006870-f5w6fw6q 6070 29 arrest arrest NN cord-006870-f5w6fw6q 6070 30 . . . cord-006870-f5w6fw6q 6071 1 He -PRON- PRP cord-006870-f5w6fw6q 6071 2 had have VBD cord-006870-f5w6fw6q 6071 3 been be VBN cord-006870-f5w6fw6q 6071 4 shopping shop VBG cord-006870-f5w6fw6q 6071 5 with with IN cord-006870-f5w6fw6q 6071 6 his -PRON- PRP$ cord-006870-f5w6fw6q 6071 7 wife wife NN cord-006870-f5w6fw6q 6071 8 when when WRB cord-006870-f5w6fw6q 6071 9 he -PRON- PRP cord-006870-f5w6fw6q 6071 10 was be VBD cord-006870-f5w6fw6q 6071 11 thought think VBN cord-006870-f5w6fw6q 6071 12 to to TO cord-006870-f5w6fw6q 6071 13 have have VB cord-006870-f5w6fw6q 6071 14 one one CD cord-006870-f5w6fw6q 6071 15 of of IN cord-006870-f5w6fw6q 6071 16 his -PRON- PRP$ cord-006870-f5w6fw6q 6071 17 typical typical JJ cord-006870-f5w6fw6q 6071 18 seizures seizure NNS cord-006870-f5w6fw6q 6071 19 . . . cord-006870-f5w6fw6q 6072 1 He -PRON- PRP cord-006870-f5w6fw6q 6072 2 was be VBD cord-006870-f5w6fw6q 6072 3 non non JJ cord-006870-f5w6fw6q 6072 4 - - JJ cord-006870-f5w6fw6q 6072 5 responsive responsive JJ cord-006870-f5w6fw6q 6072 6 for for IN cord-006870-f5w6fw6q 6072 7 about about RB cord-006870-f5w6fw6q 6072 8 20 20 CD cord-006870-f5w6fw6q 6072 9 minutes minute NNS cord-006870-f5w6fw6q 6072 10 . . . cord-006870-f5w6fw6q 6073 1 On on IN cord-006870-f5w6fw6q 6073 2 arrival arrival NN cord-006870-f5w6fw6q 6073 3 EMS EMS NNP cord-006870-f5w6fw6q 6073 4 found find VBD cord-006870-f5w6fw6q 6073 5 him -PRON- PRP cord-006870-f5w6fw6q 6073 6 pulseless pulseless JJ cord-006870-f5w6fw6q 6073 7 . . . cord-006870-f5w6fw6q 6074 1 CPR CPR NNP cord-006870-f5w6fw6q 6074 2 was be VBD cord-006870-f5w6fw6q 6074 3 started start VBN cord-006870-f5w6fw6q 6074 4 en en IN cord-006870-f5w6fw6q 6074 5 route route NN cord-006870-f5w6fw6q 6074 6 and and CC cord-006870-f5w6fw6q 6074 7 continued continue VBD cord-006870-f5w6fw6q 6074 8 for for IN cord-006870-f5w6fw6q 6074 9 30 30 CD cord-006870-f5w6fw6q 6074 10 minutes minute NNS cord-006870-f5w6fw6q 6074 11 in in IN cord-006870-f5w6fw6q 6074 12 the the DT cord-006870-f5w6fw6q 6074 13 ED ED NNP cord-006870-f5w6fw6q 6074 14 where where WRB cord-006870-f5w6fw6q 6074 15 he -PRON- PRP cord-006870-f5w6fw6q 6074 16 was be VBD cord-006870-f5w6fw6q 6074 17 defibrillated defibrillate VBN cord-006870-f5w6fw6q 6074 18 three three CD cord-006870-f5w6fw6q 6074 19 times time NNS cord-006870-f5w6fw6q 6074 20 before before IN cord-006870-f5w6fw6q 6074 21 achieving achieve VBG cord-006870-f5w6fw6q 6074 22 ROSC rosc NN cord-006870-f5w6fw6q 6074 23 . . . cord-006870-f5w6fw6q 6075 1 He -PRON- PRP cord-006870-f5w6fw6q 6075 2 completed complete VBD cord-006870-f5w6fw6q 6075 3 the the DT cord-006870-f5w6fw6q 6075 4 therapeutic therapeutic JJ cord-006870-f5w6fw6q 6075 5 hypothermia hypothermia NN cord-006870-f5w6fw6q 6075 6 protocol protocol NN cord-006870-f5w6fw6q 6075 7 . . . cord-006870-f5w6fw6q 6076 1 Cardiac cardiac JJ cord-006870-f5w6fw6q 6076 2 catheterization catheterization NN cord-006870-f5w6fw6q 6076 3 was be VBD cord-006870-f5w6fw6q 6076 4 clean clean JJ cord-006870-f5w6fw6q 6076 5 . . . cord-006870-f5w6fw6q 6077 1 EEG EEG NNP cord-006870-f5w6fw6q 6077 2 showed show VBD cord-006870-f5w6fw6q 6077 3 diffuse diffuse JJ cord-006870-f5w6fw6q 6077 4 slowing slow VBG cord-006870-f5w6fw6q 6077 5 with with IN cord-006870-f5w6fw6q 6077 6 no no DT cord-006870-f5w6fw6q 6077 7 epileptiform epileptiform NN cord-006870-f5w6fw6q 6077 8 discharges discharge NNS cord-006870-f5w6fw6q 6077 9 . . . cord-006870-f5w6fw6q 6078 1 Imaging imaging NN cord-006870-f5w6fw6q 6078 2 showed show VBD cord-006870-f5w6fw6q 6078 3 diffuse diffuse JJ cord-006870-f5w6fw6q 6078 4 anoxic anoxic JJ cord-006870-f5w6fw6q 6078 5 brain brain NN cord-006870-f5w6fw6q 6078 6 injury injury NN cord-006870-f5w6fw6q 6078 7 . . . cord-006870-f5w6fw6q 6079 1 After after IN cord-006870-f5w6fw6q 6079 2 nearly nearly RB cord-006870-f5w6fw6q 6079 3 two two CD cord-006870-f5w6fw6q 6079 4 weeks week NNS cord-006870-f5w6fw6q 6079 5 without without IN cord-006870-f5w6fw6q 6079 6 clinical clinical JJ cord-006870-f5w6fw6q 6079 7 improvement improvement NN cord-006870-f5w6fw6q 6079 8 he -PRON- PRP cord-006870-f5w6fw6q 6079 9 was be VBD cord-006870-f5w6fw6q 6079 10 made make VBN cord-006870-f5w6fw6q 6079 11 comfort comfort NN cord-006870-f5w6fw6q 6079 12 care care NN cord-006870-f5w6fw6q 6079 13 . . . cord-006870-f5w6fw6q 6079 14 . . . cord-006870-f5w6fw6q 6080 1 Of of IN cord-006870-f5w6fw6q 6080 2 note note VB cord-006870-f5w6fw6q 6080 3 , , , cord-006870-f5w6fw6q 6080 4 previous previous JJ cord-006870-f5w6fw6q 6080 5 seizure seizure NN cord-006870-f5w6fw6q 6080 6 workup workup NN cord-006870-f5w6fw6q 6080 7 failed fail VBD cord-006870-f5w6fw6q 6080 8 to to TO cord-006870-f5w6fw6q 6080 9 identify identify VB cord-006870-f5w6fw6q 6080 10 epileptiform epileptiform JJ cord-006870-f5w6fw6q 6080 11 activity activity NN cord-006870-f5w6fw6q 6080 12 . . . cord-006870-f5w6fw6q 6081 1 He -PRON- PRP cord-006870-f5w6fw6q 6081 2 was be VBD cord-006870-f5w6fw6q 6081 3 given give VBN cord-006870-f5w6fw6q 6081 4 an an DT cord-006870-f5w6fw6q 6081 5 AED AED NNP cord-006870-f5w6fw6q 6081 6 prescription prescription NN cord-006870-f5w6fw6q 6081 7 which which WDT cord-006870-f5w6fw6q 6081 8 he -PRON- PRP cord-006870-f5w6fw6q 6081 9 never never RB cord-006870-f5w6fw6q 6081 10 filled fill VBD cord-006870-f5w6fw6q 6081 11 . . . cord-006870-f5w6fw6q 6082 1 Further further JJ cord-006870-f5w6fw6q 6082 2 chart chart NN cord-006870-f5w6fw6q 6082 3 review review NN cord-006870-f5w6fw6q 6082 4 showed show VBD cord-006870-f5w6fw6q 6082 5 that that IN cord-006870-f5w6fw6q 6082 6 he -PRON- PRP cord-006870-f5w6fw6q 6082 7 had have VBD cord-006870-f5w6fw6q 6082 8 previously previously RB cord-006870-f5w6fw6q 6082 9 presented present VBN cord-006870-f5w6fw6q 6082 10 to to IN cord-006870-f5w6fw6q 6082 11 the the DT cord-006870-f5w6fw6q 6082 12 ED ED NNP cord-006870-f5w6fw6q 6082 13 after after IN cord-006870-f5w6fw6q 6082 14 a a DT cord-006870-f5w6fw6q 6082 15 " " `` cord-006870-f5w6fw6q 6082 16 seizure seizure NN cord-006870-f5w6fw6q 6082 17 " " '' cord-006870-f5w6fw6q 6082 18 episode episode NN cord-006870-f5w6fw6q 6082 19 which which WDT cord-006870-f5w6fw6q 6082 20 lasted last VBD cord-006870-f5w6fw6q 6082 21 45 45 CD cord-006870-f5w6fw6q 6082 22 minutes minute NNS cord-006870-f5w6fw6q 6082 23 . . . cord-006870-f5w6fw6q 6083 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6083 2 neuroexam neuroexam NN cord-006870-f5w6fw6q 6083 3 was be VBD cord-006870-f5w6fw6q 6083 4 non non JJ cord-006870-f5w6fw6q 6083 5 - - JJ cord-006870-f5w6fw6q 6083 6 focal focal JJ cord-006870-f5w6fw6q 6083 7 . . . cord-006870-f5w6fw6q 6084 1 CT CT NNP cord-006870-f5w6fw6q 6084 2 head head NN cord-006870-f5w6fw6q 6084 3 was be VBD cord-006870-f5w6fw6q 6084 4 negative negative JJ cord-006870-f5w6fw6q 6084 5 . . . cord-006870-f5w6fw6q 6085 1 Review Review NNP cord-006870-f5w6fw6q 6085 2 of of IN cord-006870-f5w6fw6q 6085 3 his -PRON- PRP$ cord-006870-f5w6fw6q 6085 4 EKG ekg NN cord-006870-f5w6fw6q 6085 5 at at IN cord-006870-f5w6fw6q 6085 6 that that DT cord-006870-f5w6fw6q 6085 7 time time NN cord-006870-f5w6fw6q 6085 8 showed show VBD cord-006870-f5w6fw6q 6085 9 type type NN cord-006870-f5w6fw6q 6085 10 1 1 CD cord-006870-f5w6fw6q 6085 11 Brugada Brugada NNP cord-006870-f5w6fw6q 6085 12 Syndrome Syndrome NNP cord-006870-f5w6fw6q 6085 13 pattern pattern NN cord-006870-f5w6fw6q 6085 14 with with IN cord-006870-f5w6fw6q 6085 15 an an DT cord-006870-f5w6fw6q 6085 16 elevated elevated JJ cord-006870-f5w6fw6q 6085 17 Jpoint Jpoint NNP cord-006870-f5w6fw6q 6085 18 and and CC cord-006870-f5w6fw6q 6085 19 T t NN cord-006870-f5w6fw6q 6085 20 - - HYPH cord-006870-f5w6fw6q 6085 21 wave wave NN cord-006870-f5w6fw6q 6085 22 inversions inversion NNS cord-006870-f5w6fw6q 6085 23 in in IN cord-006870-f5w6fw6q 6085 24 V1 v1 NN cord-006870-f5w6fw6q 6085 25 and and CC cord-006870-f5w6fw6q 6085 26 V2 v2 NN cord-006870-f5w6fw6q 6085 27 . . . cord-006870-f5w6fw6q 6086 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6086 2 sudden sudden JJ cord-006870-f5w6fw6q 6086 3 cardiac cardiac JJ cord-006870-f5w6fw6q 6086 4 arrest arrest NN cord-006870-f5w6fw6q 6086 5 is be VBZ cord-006870-f5w6fw6q 6086 6 most most RBS cord-006870-f5w6fw6q 6086 7 likely likely RB cord-006870-f5w6fw6q 6086 8 a a DT cord-006870-f5w6fw6q 6086 9 result result NN cord-006870-f5w6fw6q 6086 10 of of IN cord-006870-f5w6fw6q 6086 11 symptomatic symptomatic JJ cord-006870-f5w6fw6q 6086 12 Brugada Brugada NNP cord-006870-f5w6fw6q 6086 13 Symptomatic Symptomatic NNP cord-006870-f5w6fw6q 6086 14 Brugada Brugada NNP cord-006870-f5w6fw6q 6086 15 is be VBZ cord-006870-f5w6fw6q 6086 16 important important JJ cord-006870-f5w6fw6q 6086 17 to to TO cord-006870-f5w6fw6q 6086 18 identify identify VB cord-006870-f5w6fw6q 6086 19 early early RB cord-006870-f5w6fw6q 6086 20 since since IN cord-006870-f5w6fw6q 6086 21 deaths death NNS cord-006870-f5w6fw6q 6086 22 such such JJ cord-006870-f5w6fw6q 6086 23 as as IN cord-006870-f5w6fw6q 6086 24 the the DT cord-006870-f5w6fw6q 6086 25 one one NN cord-006870-f5w6fw6q 6086 26 discussed discuss VBN cord-006870-f5w6fw6q 6086 27 above above RB cord-006870-f5w6fw6q 6086 28 may may MD cord-006870-f5w6fw6q 6086 29 be be VB cord-006870-f5w6fw6q 6086 30 prevented prevent VBN cord-006870-f5w6fw6q 6086 31 by by IN cord-006870-f5w6fw6q 6086 32 an an DT cord-006870-f5w6fw6q 6086 33 implanted implant VBN cord-006870-f5w6fw6q 6086 34 defibrillator defibrillator NN cord-006870-f5w6fw6q 6086 35 . . . cord-006870-f5w6fw6q 6087 1 This this DT cord-006870-f5w6fw6q 6087 2 case case NN cord-006870-f5w6fw6q 6087 3 highlights highlight VBZ cord-006870-f5w6fw6q 6087 4 the the DT cord-006870-f5w6fw6q 6087 5 need need NN cord-006870-f5w6fw6q 6087 6 for for IN cord-006870-f5w6fw6q 6087 7 heightened heightened JJ cord-006870-f5w6fw6q 6087 8 awareness awareness NN cord-006870-f5w6fw6q 6087 9 and and CC cord-006870-f5w6fw6q 6087 10 more more RBR cord-006870-f5w6fw6q 6087 11 effective effective JJ cord-006870-f5w6fw6q 6087 12 testing testing NN cord-006870-f5w6fw6q 6087 13 for for IN cord-006870-f5w6fw6q 6087 14 Brugada Brugada NNP cord-006870-f5w6fw6q 6087 15 in in IN cord-006870-f5w6fw6q 6087 16 the the DT cord-006870-f5w6fw6q 6087 17 setting setting NN cord-006870-f5w6fw6q 6087 18 of of IN cord-006870-f5w6fw6q 6087 19 seizure seizure NN cord-006870-f5w6fw6q 6087 20 or or CC cord-006870-f5w6fw6q 6087 21 pseudoseizure pseudoseizure NN cord-006870-f5w6fw6q 6087 22 . . . cord-006870-f5w6fw6q 6088 1 Patients patient NNS cord-006870-f5w6fw6q 6088 2 with with IN cord-006870-f5w6fw6q 6088 3 cerebral cerebral JJ cord-006870-f5w6fw6q 6088 4 air air NN cord-006870-f5w6fw6q 6088 5 embolism embolism NN cord-006870-f5w6fw6q 6088 6 ( ( -LRB- cord-006870-f5w6fw6q 6088 7 CAE CAE NNP cord-006870-f5w6fw6q 6088 8 ) ) -RRB- cord-006870-f5w6fw6q 6088 9 often often RB cord-006870-f5w6fw6q 6088 10 exhibit exhibit VBP cord-006870-f5w6fw6q 6088 11 more more RBR cord-006870-f5w6fw6q 6088 12 severe severe JJ cord-006870-f5w6fw6q 6088 13 symptoms symptom NNS cord-006870-f5w6fw6q 6088 14 than than IN cord-006870-f5w6fw6q 6088 15 those those DT cord-006870-f5w6fw6q 6088 16 typically typically RB cord-006870-f5w6fw6q 6088 17 associated associate VBN cord-006870-f5w6fw6q 6088 18 with with IN cord-006870-f5w6fw6q 6088 19 the the DT cord-006870-f5w6fw6q 6088 20 number number NN cord-006870-f5w6fw6q 6088 21 of of IN cord-006870-f5w6fw6q 6088 22 air air NN cord-006870-f5w6fw6q 6088 23 emboli embolus NNS cord-006870-f5w6fw6q 6088 24 and and CC cord-006870-f5w6fw6q 6088 25 size size NN cord-006870-f5w6fw6q 6088 26 of of IN cord-006870-f5w6fw6q 6088 27 infarcts infarct NNS cord-006870-f5w6fw6q 6088 28 on on IN cord-006870-f5w6fw6q 6088 29 brain brain NN cord-006870-f5w6fw6q 6088 30 images image NNS cord-006870-f5w6fw6q 6088 31 . . . cord-006870-f5w6fw6q 6089 1 However however RB cord-006870-f5w6fw6q 6089 2 , , , cord-006870-f5w6fw6q 6089 3 this this DT cord-006870-f5w6fw6q 6089 4 discrepancy discrepancy NN cord-006870-f5w6fw6q 6089 5 between between IN cord-006870-f5w6fw6q 6089 6 symptoms symptom NNS cord-006870-f5w6fw6q 6089 7 and and CC cord-006870-f5w6fw6q 6089 8 imaging image VBG cord-006870-f5w6fw6q 6089 9 findings finding NNS cord-006870-f5w6fw6q 6089 10 has have VBZ cord-006870-f5w6fw6q 6089 11 not not RB cord-006870-f5w6fw6q 6089 12 been be VBN cord-006870-f5w6fw6q 6089 13 sufficiently sufficiently RB cord-006870-f5w6fw6q 6089 14 explained explain VBN cord-006870-f5w6fw6q 6089 15 . . . cord-006870-f5w6fw6q 6090 1 We -PRON- PRP cord-006870-f5w6fw6q 6090 2 report report VBP cord-006870-f5w6fw6q 6090 3 a a DT cord-006870-f5w6fw6q 6090 4 case case NN cord-006870-f5w6fw6q 6090 5 of of IN cord-006870-f5w6fw6q 6090 6 CAE CAE NNP cord-006870-f5w6fw6q 6090 7 in in IN cord-006870-f5w6fw6q 6090 8 which which WDT cord-006870-f5w6fw6q 6090 9 disruption disruption NN cord-006870-f5w6fw6q 6090 10 of of IN cord-006870-f5w6fw6q 6090 11 the the DT cord-006870-f5w6fw6q 6090 12 blood blood NN cord-006870-f5w6fw6q 6090 13 - - HYPH cord-006870-f5w6fw6q 6090 14 brain brain NN cord-006870-f5w6fw6q 6090 15 barrier barrier NN cord-006870-f5w6fw6q 6090 16 ( ( -LRB- cord-006870-f5w6fw6q 6090 17 BBB BBB NNP cord-006870-f5w6fw6q 6090 18 ) ) -RRB- cord-006870-f5w6fw6q 6090 19 and and CC cord-006870-f5w6fw6q 6090 20 perfusion perfusion NN cord-006870-f5w6fw6q 6090 21 defects defect NNS cord-006870-f5w6fw6q 6090 22 were be VBD cord-006870-f5w6fw6q 6090 23 identified identify VBN cord-006870-f5w6fw6q 6090 24 via via IN cord-006870-f5w6fw6q 6090 25 brain brain NN cord-006870-f5w6fw6q 6090 26 magnetic magnetic JJ cord-006870-f5w6fw6q 6090 27 resonance resonance NN cord-006870-f5w6fw6q 6090 28 imaging imaging NN cord-006870-f5w6fw6q 6090 29 ( ( -LRB- cord-006870-f5w6fw6q 6090 30 MRI MRI NNP cord-006870-f5w6fw6q 6090 31 ) ) -RRB- cord-006870-f5w6fw6q 6090 32 . . . cord-006870-f5w6fw6q 6091 1 A a DT cord-006870-f5w6fw6q 6091 2 79-year 79-year JJ cord-006870-f5w6fw6q 6091 3 old old JJ cord-006870-f5w6fw6q 6091 4 man man NN cord-006870-f5w6fw6q 6091 5 with with IN cord-006870-f5w6fw6q 6091 6 a a DT cord-006870-f5w6fw6q 6091 7 lung lung NN cord-006870-f5w6fw6q 6091 8 mass mass NN cord-006870-f5w6fw6q 6091 9 was be VBD cord-006870-f5w6fw6q 6091 10 admitted admit VBN cord-006870-f5w6fw6q 6091 11 to to IN cord-006870-f5w6fw6q 6091 12 our -PRON- PRP$ cord-006870-f5w6fw6q 6091 13 hospital hospital NN cord-006870-f5w6fw6q 6091 14 . . . cord-006870-f5w6fw6q 6092 1 Percutaneous percutaneous JJ cord-006870-f5w6fw6q 6092 2 needle needle NN cord-006870-f5w6fw6q 6092 3 aspiration aspiration NN cord-006870-f5w6fw6q 6092 4 of of IN cord-006870-f5w6fw6q 6092 5 the the DT cord-006870-f5w6fw6q 6092 6 mass mass NN cord-006870-f5w6fw6q 6092 7 was be VBD cord-006870-f5w6fw6q 6092 8 performed perform VBN cord-006870-f5w6fw6q 6092 9 in in IN cord-006870-f5w6fw6q 6092 10 the the DT cord-006870-f5w6fw6q 6092 11 left left JJ cord-006870-f5w6fw6q 6092 12 lower low JJR cord-006870-f5w6fw6q 6092 13 lobe lobe NN cord-006870-f5w6fw6q 6092 14 of of IN cord-006870-f5w6fw6q 6092 15 the the DT cord-006870-f5w6fw6q 6092 16 lung lung NN cord-006870-f5w6fw6q 6092 17 . . . cord-006870-f5w6fw6q 6093 1 The the DT cord-006870-f5w6fw6q 6093 2 patient patient NN cord-006870-f5w6fw6q 6093 3 developed develop VBD cord-006870-f5w6fw6q 6093 4 sudden sudden JJ cord-006870-f5w6fw6q 6093 5 confusion confusion NN cord-006870-f5w6fw6q 6093 6 and and CC cord-006870-f5w6fw6q 6093 7 irritability irritability NN cord-006870-f5w6fw6q 6093 8 after after IN cord-006870-f5w6fw6q 6093 9 the the DT cord-006870-f5w6fw6q 6093 10 procedure procedure NN cord-006870-f5w6fw6q 6093 11 . . . cord-006870-f5w6fw6q 6094 1 During during IN cord-006870-f5w6fw6q 6094 2 neurological neurological JJ cord-006870-f5w6fw6q 6094 3 examination examination NN cord-006870-f5w6fw6q 6094 4 , , , cord-006870-f5w6fw6q 6094 5 he -PRON- PRP cord-006870-f5w6fw6q 6094 6 could could MD cord-006870-f5w6fw6q 6094 7 follow follow VB cord-006870-f5w6fw6q 6094 8 only only RB cord-006870-f5w6fw6q 6094 9 simple simple JJ cord-006870-f5w6fw6q 6094 10 commands command NNS cord-006870-f5w6fw6q 6094 11 and and CC cord-006870-f5w6fw6q 6094 12 exhibited exhibit VBD cord-006870-f5w6fw6q 6094 13 symptoms symptom NNS cord-006870-f5w6fw6q 6094 14 of of IN cord-006870-f5w6fw6q 6094 15 left left JJ cord-006870-f5w6fw6q 6094 16 - - HYPH cord-006870-f5w6fw6q 6094 17 sided sided JJ cord-006870-f5w6fw6q 6094 18 weakness weakness NN cord-006870-f5w6fw6q 6094 19 and and CC cord-006870-f5w6fw6q 6094 20 neglect neglect JJ cord-006870-f5w6fw6q 6094 21 ( ( -LRB- cord-006870-f5w6fw6q 6094 22 Medical Medical NNP cord-006870-f5w6fw6q 6094 23 Research Research NNP cord-006870-f5w6fw6q 6094 24 Council Council NNP cord-006870-f5w6fw6q 6094 25 grade grade NN cord-006870-f5w6fw6q 6094 26 2 2 CD cord-006870-f5w6fw6q 6094 27 ) ) -RRB- cord-006870-f5w6fw6q 6094 28 . . . cord-006870-f5w6fw6q 6095 1 Noncontrast Noncontrast NNP cord-006870-f5w6fw6q 6095 2 computed compute VBN cord-006870-f5w6fw6q 6095 3 tomography tomography NN cord-006870-f5w6fw6q 6095 4 ( ( -LRB- cord-006870-f5w6fw6q 6095 5 CT CT NNP cord-006870-f5w6fw6q 6095 6 ) ) -RRB- cord-006870-f5w6fw6q 6095 7 of of IN cord-006870-f5w6fw6q 6095 8 the the DT cord-006870-f5w6fw6q 6095 9 brain brain NN cord-006870-f5w6fw6q 6096 1 revealed reveal VBD cord-006870-f5w6fw6q 6096 2 a a DT cord-006870-f5w6fw6q 6096 3 few few JJ cord-006870-f5w6fw6q 6096 4 small small JJ cord-006870-f5w6fw6q 6096 5 air air NN cord-006870-f5w6fw6q 6096 6 emboli embolus NNS cord-006870-f5w6fw6q 6096 7 in in IN cord-006870-f5w6fw6q 6096 8 the the DT cord-006870-f5w6fw6q 6096 9 right right JJ cord-006870-f5w6fw6q 6096 10 frontal frontal JJ cord-006870-f5w6fw6q 6096 11 subcortical subcortical JJ cord-006870-f5w6fw6q 6096 12 area area NN cord-006870-f5w6fw6q 6096 13 . . . cord-006870-f5w6fw6q 6097 1 Multimodal Multimodal NNP cord-006870-f5w6fw6q 6097 2 MRI MRI NNP cord-006870-f5w6fw6q 6097 3 of of IN cord-006870-f5w6fw6q 6097 4 the the DT cord-006870-f5w6fw6q 6097 5 brain brain NN cord-006870-f5w6fw6q 6097 6 was be VBD cord-006870-f5w6fw6q 6097 7 performed perform VBN cord-006870-f5w6fw6q 6097 8 50 50 CD cord-006870-f5w6fw6q 6097 9 minutes minute NNS cord-006870-f5w6fw6q 6097 10 after after IN cord-006870-f5w6fw6q 6097 11 the the DT cord-006870-f5w6fw6q 6097 12 onset onset NN cord-006870-f5w6fw6q 6097 13 of of IN cord-006870-f5w6fw6q 6097 14 symptoms symptom NNS cord-006870-f5w6fw6q 6097 15 . . . cord-006870-f5w6fw6q 6098 1 T2-weighted t2-weighte VBN cord-006870-f5w6fw6q 6098 2 gradient gradient NN cord-006870-f5w6fw6q 6098 3 - - HYPH cord-006870-f5w6fw6q 6098 4 echo echo NN cord-006870-f5w6fw6q 6098 5 imaging imaging NN cord-006870-f5w6fw6q 6098 6 revealed reveal VBD cord-006870-f5w6fw6q 6098 7 only only RB cord-006870-f5w6fw6q 6098 8 a a DT cord-006870-f5w6fw6q 6098 9 few few JJ cord-006870-f5w6fw6q 6098 10 small small JJ cord-006870-f5w6fw6q 6098 11 air air NN cord-006870-f5w6fw6q 6098 12 emboli embolus NNS cord-006870-f5w6fw6q 6098 13 in in IN cord-006870-f5w6fw6q 6098 14 the the DT cord-006870-f5w6fw6q 6098 15 right right JJ cord-006870-f5w6fw6q 6098 16 frontal frontal JJ cord-006870-f5w6fw6q 6098 17 area area NN cord-006870-f5w6fw6q 6098 18 , , , cord-006870-f5w6fw6q 6098 19 and and CC cord-006870-f5w6fw6q 6098 20 diffusion diffusion NN cord-006870-f5w6fw6q 6098 21 - - HYPH cord-006870-f5w6fw6q 6098 22 weighted weight VBN cord-006870-f5w6fw6q 6098 23 imaging imaging NN cord-006870-f5w6fw6q 6098 24 findings finding NNS cord-006870-f5w6fw6q 6098 25 were be VBD cord-006870-f5w6fw6q 6098 26 unremarkable unremarkable JJ cord-006870-f5w6fw6q 6098 27 . . . cord-006870-f5w6fw6q 6099 1 In in IN cord-006870-f5w6fw6q 6099 2 contrast contrast NN cord-006870-f5w6fw6q 6099 3 , , , cord-006870-f5w6fw6q 6099 4 time time NN cord-006870-f5w6fw6q 6099 5 - - HYPH cord-006870-f5w6fw6q 6099 6 to to IN cord-006870-f5w6fw6q 6099 7 - - HYPH cord-006870-f5w6fw6q 6099 8 peak peak NN cord-006870-f5w6fw6q 6099 9 imaging imaging NN cord-006870-f5w6fw6q 6099 10 revealed reveal VBD cord-006870-f5w6fw6q 6099 11 widely widely RB cord-006870-f5w6fw6q 6099 12 distributed distribute VBN cord-006870-f5w6fw6q 6099 13 perfusion perfusion NN cord-006870-f5w6fw6q 6099 14 defects defect NNS cord-006870-f5w6fw6q 6099 15 in in IN cord-006870-f5w6fw6q 6099 16 the the DT cord-006870-f5w6fw6q 6099 17 right right JJ cord-006870-f5w6fw6q 6099 18 hemisphere hemisphere NN cord-006870-f5w6fw6q 6099 19 , , , cord-006870-f5w6fw6q 6099 20 while while IN cord-006870-f5w6fw6q 6099 21 contrast contrast NN cord-006870-f5w6fw6q 6099 22 - - HYPH cord-006870-f5w6fw6q 6099 23 enhanced enhance VBN cord-006870-f5w6fw6q 6099 24 T1-weighted t1-weighte VBN cord-006870-f5w6fw6q 6099 25 imaging imaging NN cord-006870-f5w6fw6q 6099 26 revealed reveal VBD cord-006870-f5w6fw6q 6099 27 prominent prominent JJ cord-006870-f5w6fw6q 6099 28 leptomeningeal leptomeningeal NN cord-006870-f5w6fw6q 6099 29 enhancement enhancement NN cord-006870-f5w6fw6q 6099 30 , , , cord-006870-f5w6fw6q 6099 31 suggestive suggestive JJ cord-006870-f5w6fw6q 6099 32 of of IN cord-006870-f5w6fw6q 6099 33 BBB BBB NNP cord-006870-f5w6fw6q 6099 34 disruption disruption NN cord-006870-f5w6fw6q 6099 35 in in IN cord-006870-f5w6fw6q 6099 36 the the DT cord-006870-f5w6fw6q 6099 37 right right JJ cord-006870-f5w6fw6q 6099 38 hemisphere hemisphere NN cord-006870-f5w6fw6q 6099 39 . . . cord-006870-f5w6fw6q 6100 1 Magnetic magnetic JJ cord-006870-f5w6fw6q 6100 2 resonance resonance NN cord-006870-f5w6fw6q 6100 3 angiography angiography NN cord-006870-f5w6fw6q 6100 4 revealed reveal VBD cord-006870-f5w6fw6q 6100 5 no no DT cord-006870-f5w6fw6q 6100 6 steno steno NN cord-006870-f5w6fw6q 6100 7 - - HYPH cord-006870-f5w6fw6q 6100 8 occlusive occlusive JJ cord-006870-f5w6fw6q 6100 9 lesions lesion NNS cord-006870-f5w6fw6q 6100 10 . . . cord-006870-f5w6fw6q 6101 1 The the DT cord-006870-f5w6fw6q 6101 2 patient patient NN cord-006870-f5w6fw6q 6101 3 was be VBD cord-006870-f5w6fw6q 6101 4 treated treat VBN cord-006870-f5w6fw6q 6101 5 with with IN cord-006870-f5w6fw6q 6101 6 100 100 CD cord-006870-f5w6fw6q 6101 7 % % NN cord-006870-f5w6fw6q 6101 8 oxygen oxygen NN cord-006870-f5w6fw6q 6101 9 via via IN cord-006870-f5w6fw6q 6101 10 a a DT cord-006870-f5w6fw6q 6101 11 high high JJ cord-006870-f5w6fw6q 6101 12 - - HYPH cord-006870-f5w6fw6q 6101 13 flow flow NN cord-006870-f5w6fw6q 6101 14 nasal nasal NN cord-006870-f5w6fw6q 6101 15 cannula cannula NN cord-006870-f5w6fw6q 6101 16 . . . cord-006870-f5w6fw6q 6102 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6102 2 weakness weakness NN cord-006870-f5w6fw6q 6102 3 subsided subside VBD cord-006870-f5w6fw6q 6102 4 the the DT cord-006870-f5w6fw6q 6102 5 next next JJ cord-006870-f5w6fw6q 6102 6 day day NN cord-006870-f5w6fw6q 6102 7 , , , cord-006870-f5w6fw6q 6102 8 although although IN cord-006870-f5w6fw6q 6102 9 his -PRON- PRP$ cord-006870-f5w6fw6q 6102 10 confusion confusion NN cord-006870-f5w6fw6q 6102 11 persisted persist VBD cord-006870-f5w6fw6q 6102 12 for for IN cord-006870-f5w6fw6q 6102 13 18 18 CD cord-006870-f5w6fw6q 6102 14 days day NNS cord-006870-f5w6fw6q 6102 15 . . . cord-006870-f5w6fw6q 6103 1 Follow follow VB cord-006870-f5w6fw6q 6103 2 - - HYPH cord-006870-f5w6fw6q 6103 3 up up RP cord-006870-f5w6fw6q 6103 4 MRI MRI NNP cord-006870-f5w6fw6q 6103 5 performed perform VBD cord-006870-f5w6fw6q 6103 6 five five CD cord-006870-f5w6fw6q 6103 7 days day NNS cord-006870-f5w6fw6q 6103 8 after after IN cord-006870-f5w6fw6q 6103 9 the the DT cord-006870-f5w6fw6q 6103 10 onset onset NN cord-006870-f5w6fw6q 6103 11 of of IN cord-006870-f5w6fw6q 6103 12 symptoms symptom NNS cord-006870-f5w6fw6q 6103 13 revealed reveal VBD cord-006870-f5w6fw6q 6103 14 resolution resolution NN cord-006870-f5w6fw6q 6103 15 of of IN cord-006870-f5w6fw6q 6103 16 the the DT cord-006870-f5w6fw6q 6103 17 abnormal abnormal JJ cord-006870-f5w6fw6q 6103 18 findings finding NNS cord-006870-f5w6fw6q 6103 19 . . . cord-006870-f5w6fw6q 6104 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6104 2 findings finding NNS cord-006870-f5w6fw6q 6104 3 suggest suggest VBP cord-006870-f5w6fw6q 6104 4 that that IN cord-006870-f5w6fw6q 6104 5 disruption disruption NN cord-006870-f5w6fw6q 6104 6 of of IN cord-006870-f5w6fw6q 6104 7 BBB bbb NN cord-006870-f5w6fw6q 6104 8 and and CC cord-006870-f5w6fw6q 6104 9 perfusion perfusion NN cord-006870-f5w6fw6q 6104 10 defects defect NNS cord-006870-f5w6fw6q 6104 11 may may MD cord-006870-f5w6fw6q 6104 12 develop develop VB cord-006870-f5w6fw6q 6104 13 in in IN cord-006870-f5w6fw6q 6104 14 patients patient NNS cord-006870-f5w6fw6q 6104 15 with with IN cord-006870-f5w6fw6q 6104 16 CAE CAE NNP cord-006870-f5w6fw6q 6104 17 . . . cord-006870-f5w6fw6q 6105 1 Extensive extensive JJ cord-006870-f5w6fw6q 6105 2 impairments impairment NNS cord-006870-f5w6fw6q 6105 3 of of IN cord-006870-f5w6fw6q 6105 4 the the DT cord-006870-f5w6fw6q 6105 5 BBB BBB NNP cord-006870-f5w6fw6q 6105 6 and and CC cord-006870-f5w6fw6q 6105 7 perfusion perfusion NN cord-006870-f5w6fw6q 6105 8 may may MD cord-006870-f5w6fw6q 6105 9 explain explain VB cord-006870-f5w6fw6q 6105 10 the the DT cord-006870-f5w6fw6q 6105 11 mismatch mismatch NN cord-006870-f5w6fw6q 6105 12 between between IN cord-006870-f5w6fw6q 6105 13 severe severe JJ cord-006870-f5w6fw6q 6105 14 neurological neurological JJ cord-006870-f5w6fw6q 6105 15 symptoms symptom NNS cord-006870-f5w6fw6q 6105 16 and and CC cord-006870-f5w6fw6q 6105 17 small small JJ cord-006870-f5w6fw6q 6105 18 air air NN cord-006870-f5w6fw6q 6105 19 emboli embolus NNS cord-006870-f5w6fw6q 6105 20 / / SYM cord-006870-f5w6fw6q 6105 21 infarcts infarct NNS cord-006870-f5w6fw6q 6105 22 . . . cord-006870-f5w6fw6q 6106 1 Co co NN cord-006870-f5w6fw6q 6106 2 - - NN cord-006870-f5w6fw6q 6106 3 existence existence NN cord-006870-f5w6fw6q 6106 4 of of IN cord-006870-f5w6fw6q 6106 5 cerebral cerebral JJ cord-006870-f5w6fw6q 6106 6 salt salt NN cord-006870-f5w6fw6q 6106 7 wasting wasting NN cord-006870-f5w6fw6q 6106 8 and and CC cord-006870-f5w6fw6q 6106 9 diabetes diabetes NN cord-006870-f5w6fw6q 6106 10 insipidus insipidus NN cord-006870-f5w6fw6q 6106 11 is be VBZ cord-006870-f5w6fw6q 6106 12 an an DT cord-006870-f5w6fw6q 6106 13 extremely extremely RB cord-006870-f5w6fw6q 6106 14 rare rare JJ cord-006870-f5w6fw6q 6106 15 entity entity NN cord-006870-f5w6fw6q 6106 16 that that WDT cord-006870-f5w6fw6q 6106 17 has have VBZ cord-006870-f5w6fw6q 6106 18 only only RB cord-006870-f5w6fw6q 6106 19 been be VBN cord-006870-f5w6fw6q 6106 20 described describe VBN cord-006870-f5w6fw6q 6106 21 in in IN cord-006870-f5w6fw6q 6106 22 2 2 CD cord-006870-f5w6fw6q 6106 23 adult adult NN cord-006870-f5w6fw6q 6106 24 case case NN cord-006870-f5w6fw6q 6106 25 series series NN cord-006870-f5w6fw6q 6106 26 and and CC cord-006870-f5w6fw6q 6106 27 a a DT cord-006870-f5w6fw6q 6106 28 paediatric paediatric JJ cord-006870-f5w6fw6q 6106 29 series series NN cord-006870-f5w6fw6q 6106 30 . . . cord-006870-f5w6fw6q 6107 1 Due due IN cord-006870-f5w6fw6q 6107 2 to to IN cord-006870-f5w6fw6q 6107 3 the the DT cord-006870-f5w6fw6q 6107 4 complex complex JJ cord-006870-f5w6fw6q 6107 5 nature nature NN cord-006870-f5w6fw6q 6107 6 of of IN cord-006870-f5w6fw6q 6107 7 diagnosing diagnose VBG cord-006870-f5w6fw6q 6107 8 this this DT cord-006870-f5w6fw6q 6107 9 entity entity NN cord-006870-f5w6fw6q 6107 10 , , , cord-006870-f5w6fw6q 6107 11 mistreatment mistreatment NN cord-006870-f5w6fw6q 6107 12 may may MD cord-006870-f5w6fw6q 6107 13 ensue ensue VB cord-006870-f5w6fw6q 6107 14 and and CC cord-006870-f5w6fw6q 6107 15 lead lead VB cord-006870-f5w6fw6q 6107 16 to to IN cord-006870-f5w6fw6q 6107 17 high high JJ cord-006870-f5w6fw6q 6107 18 morbidity morbidity NN cord-006870-f5w6fw6q 6107 19 and and CC cord-006870-f5w6fw6q 6107 20 mortality mortality NN cord-006870-f5w6fw6q 6107 21 rates rate NNS cord-006870-f5w6fw6q 6107 22 . . . cord-006870-f5w6fw6q 6108 1 We -PRON- PRP cord-006870-f5w6fw6q 6108 2 report report VBP cord-006870-f5w6fw6q 6108 3 a a DT cord-006870-f5w6fw6q 6108 4 case case NN cord-006870-f5w6fw6q 6108 5 of of IN cord-006870-f5w6fw6q 6108 6 a a DT cord-006870-f5w6fw6q 6108 7 patient patient NN cord-006870-f5w6fw6q 6108 8 who who WP cord-006870-f5w6fw6q 6108 9 was be VBD cord-006870-f5w6fw6q 6108 10 admitted admit VBN cord-006870-f5w6fw6q 6108 11 to to IN cord-006870-f5w6fw6q 6108 12 the the DT cord-006870-f5w6fw6q 6108 13 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 6108 14 intensive intensive JJ cord-006870-f5w6fw6q 6108 15 care care NN cord-006870-f5w6fw6q 6108 16 unit unit NN cord-006870-f5w6fw6q 6108 17 after after IN cord-006870-f5w6fw6q 6108 18 sustaining sustain VBG cord-006870-f5w6fw6q 6108 19 a a DT cord-006870-f5w6fw6q 6108 20 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6108 21 haemorrhage haemorrhage NN cord-006870-f5w6fw6q 6108 22 secondary secondary JJ cord-006870-f5w6fw6q 6108 23 to to IN cord-006870-f5w6fw6q 6108 24 a a DT cord-006870-f5w6fw6q 6108 25 ruptured rupture VBN cord-006870-f5w6fw6q 6108 26 anterior anterior JJ cord-006870-f5w6fw6q 6108 27 communicating communicate VBG cord-006870-f5w6fw6q 6108 28 artery artery NN cord-006870-f5w6fw6q 6108 29 aneurysm aneurysm NN cord-006870-f5w6fw6q 6108 30 . . . cord-006870-f5w6fw6q 6109 1 A a DT cord-006870-f5w6fw6q 6109 2 67-year 67-year JJ cord-006870-f5w6fw6q 6109 3 old old JJ cord-006870-f5w6fw6q 6109 4 lady lady NN cord-006870-f5w6fw6q 6109 5 presented present VBN cord-006870-f5w6fw6q 6109 6 with with IN cord-006870-f5w6fw6q 6109 7 sudden sudden JJ cord-006870-f5w6fw6q 6109 8 onset onset NN cord-006870-f5w6fw6q 6109 9 of of IN cord-006870-f5w6fw6q 6109 10 severe severe JJ cord-006870-f5w6fw6q 6109 11 headache headache NN cord-006870-f5w6fw6q 6109 12 and and CC cord-006870-f5w6fw6q 6109 13 nausea nausea NN cord-006870-f5w6fw6q 6109 14 . . . cord-006870-f5w6fw6q 6110 1 GCS GCS NNP cord-006870-f5w6fw6q 6110 2 was be VBD cord-006870-f5w6fw6q 6110 3 12 12 CD cord-006870-f5w6fw6q 6111 1 ( ( -LRB- cord-006870-f5w6fw6q 6111 2 E3V4M5 E3V4M5 NNP cord-006870-f5w6fw6q 6111 3 ) ) -RRB- cord-006870-f5w6fw6q 6112 1 with with IN cord-006870-f5w6fw6q 6112 2 no no DT cord-006870-f5w6fw6q 6112 3 focal focal JJ cord-006870-f5w6fw6q 6112 4 neurological neurological JJ cord-006870-f5w6fw6q 6112 5 deficits deficit NNS cord-006870-f5w6fw6q 6112 6 . . . cord-006870-f5w6fw6q 6113 1 She -PRON- PRP cord-006870-f5w6fw6q 6113 2 underwent undergo VBD cord-006870-f5w6fw6q 6113 3 endovascular endovascular JJ cord-006870-f5w6fw6q 6113 4 coiling coiling NN cord-006870-f5w6fw6q 6113 5 and and CC cord-006870-f5w6fw6q 6113 6 embolisation embolisation NN cord-006870-f5w6fw6q 6113 7 of of IN cord-006870-f5w6fw6q 6113 8 the the DT cord-006870-f5w6fw6q 6113 9 aneurysm aneurysm NN cord-006870-f5w6fw6q 6113 10 under under IN cord-006870-f5w6fw6q 6113 11 general general JJ cord-006870-f5w6fw6q 6113 12 anaesthesia anaesthesia NN cord-006870-f5w6fw6q 6113 13 and and CC cord-006870-f5w6fw6q 6113 14 had have VBD cord-006870-f5w6fw6q 6113 15 a a DT cord-006870-f5w6fw6q 6113 16 left left JJ cord-006870-f5w6fw6q 6113 17 external external JJ cord-006870-f5w6fw6q 6113 18 ventricular ventricular JJ cord-006870-f5w6fw6q 6113 19 drain drain NN cord-006870-f5w6fw6q 6113 20 inserted insert VBN cord-006870-f5w6fw6q 6113 21 . . . cord-006870-f5w6fw6q 6114 1 In in IN cord-006870-f5w6fw6q 6114 2 the the DT cord-006870-f5w6fw6q 6114 3 immediate immediate JJ cord-006870-f5w6fw6q 6114 4 postoperative postoperative JJ cord-006870-f5w6fw6q 6114 5 period period NN cord-006870-f5w6fw6q 6114 6 , , , cord-006870-f5w6fw6q 6114 7 she -PRON- PRP cord-006870-f5w6fw6q 6114 8 was be VBD cord-006870-f5w6fw6q 6114 9 found find VBN cord-006870-f5w6fw6q 6114 10 to to TO cord-006870-f5w6fw6q 6114 11 be be VB cord-006870-f5w6fw6q 6114 12 polyuric polyuric NNP cord-006870-f5w6fw6q 6114 13 , , , cord-006870-f5w6fw6q 6114 14 with with IN cord-006870-f5w6fw6q 6114 15 the the DT cord-006870-f5w6fw6q 6114 16 initial initial JJ cord-006870-f5w6fw6q 6114 17 workup workup NN cord-006870-f5w6fw6q 6114 18 suggestive suggestive JJ cord-006870-f5w6fw6q 6114 19 of of IN cord-006870-f5w6fw6q 6114 20 diabetes diabetes NN cord-006870-f5w6fw6q 6114 21 insipidus insipidus NN cord-006870-f5w6fw6q 6114 22 . . . cord-006870-f5w6fw6q 6115 1 Desmopressin Desmopressin NNP cord-006870-f5w6fw6q 6115 2 was be VBD cord-006870-f5w6fw6q 6115 3 administered administer VBN cord-006870-f5w6fw6q 6115 4 with with IN cord-006870-f5w6fw6q 6115 5 initial initial JJ cord-006870-f5w6fw6q 6115 6 good good JJ cord-006870-f5w6fw6q 6115 7 effect effect NN cord-006870-f5w6fw6q 6115 8 . . . cord-006870-f5w6fw6q 6116 1 However however RB cord-006870-f5w6fw6q 6116 2 , , , cord-006870-f5w6fw6q 6116 3 her -PRON- PRP$ cord-006870-f5w6fw6q 6116 4 polyuria polyuria NN cord-006870-f5w6fw6q 6116 5 recurred recur VBD cord-006870-f5w6fw6q 6116 6 and and CC cord-006870-f5w6fw6q 6116 7 persisted persist VBD cord-006870-f5w6fw6q 6116 8 despite despite IN cord-006870-f5w6fw6q 6116 9 Desmopressin Desmopressin NNP cord-006870-f5w6fw6q 6116 10 . . . cord-006870-f5w6fw6q 6117 1 The the DT cord-006870-f5w6fw6q 6117 2 repeat repeat NN cord-006870-f5w6fw6q 6117 3 workup workup NN cord-006870-f5w6fw6q 6117 4 revealed reveal VBD cord-006870-f5w6fw6q 6117 5 the the DT cord-006870-f5w6fw6q 6117 6 presence presence NN cord-006870-f5w6fw6q 6117 7 of of IN cord-006870-f5w6fw6q 6117 8 concomitant concomitant JJ cord-006870-f5w6fw6q 6117 9 cerebral cerebral JJ cord-006870-f5w6fw6q 6117 10 saltwasting saltwasting NN cord-006870-f5w6fw6q 6117 11 . . . cord-006870-f5w6fw6q 6118 1 She -PRON- PRP cord-006870-f5w6fw6q 6118 2 was be VBD cord-006870-f5w6fw6q 6118 3 then then RB cord-006870-f5w6fw6q 6118 4 treated treat VBN cord-006870-f5w6fw6q 6118 5 with with IN cord-006870-f5w6fw6q 6118 6 fludrocortisone fludrocortisone NN cord-006870-f5w6fw6q 6118 7 and and CC cord-006870-f5w6fw6q 6118 8 sodium sodium NN cord-006870-f5w6fw6q 6118 9 chloride chloride NN cord-006870-f5w6fw6q 6118 10 supplementation supplementation NN cord-006870-f5w6fw6q 6118 11 . . . cord-006870-f5w6fw6q 6119 1 Careful careful JJ cord-006870-f5w6fw6q 6119 2 monitoring monitoring NN cord-006870-f5w6fw6q 6119 3 of of IN cord-006870-f5w6fw6q 6119 4 her -PRON- PRP$ cord-006870-f5w6fw6q 6119 5 serum serum NN cord-006870-f5w6fw6q 6119 6 sodium sodium NN cord-006870-f5w6fw6q 6119 7 levels level NNS cord-006870-f5w6fw6q 6119 8 and and CC cord-006870-f5w6fw6q 6119 9 overall overall JJ cord-006870-f5w6fw6q 6119 10 fluid fluid JJ cord-006870-f5w6fw6q 6119 11 balance balance NN cord-006870-f5w6fw6q 6119 12 allowed allow VBD cord-006870-f5w6fw6q 6119 13 close close JJ cord-006870-f5w6fw6q 6119 14 titration titration NN cord-006870-f5w6fw6q 6119 15 of of IN cord-006870-f5w6fw6q 6119 16 the the DT cord-006870-f5w6fw6q 6119 17 Desmopressin Desmopressin NNP cord-006870-f5w6fw6q 6119 18 , , , cord-006870-f5w6fw6q 6119 19 fludrocortisone fludrocortisone NN cord-006870-f5w6fw6q 6119 20 and and CC cord-006870-f5w6fw6q 6119 21 sodium sodium NN cord-006870-f5w6fw6q 6119 22 chloride chloride NN cord-006870-f5w6fw6q 6119 23 supplementation supplementation NN cord-006870-f5w6fw6q 6119 24 . . . cord-006870-f5w6fw6q 6120 1 She -PRON- PRP cord-006870-f5w6fw6q 6120 2 was be VBD cord-006870-f5w6fw6q 6120 3 eventually eventually RB cord-006870-f5w6fw6q 6120 4 weaned wean VBN cord-006870-f5w6fw6q 6120 5 off off RP cord-006870-f5w6fw6q 6120 6 treatment treatment NN cord-006870-f5w6fw6q 6120 7 and and CC cord-006870-f5w6fw6q 6120 8 discharged discharge VBN cord-006870-f5w6fw6q 6120 9 well well RB cord-006870-f5w6fw6q 6120 10 with with IN cord-006870-f5w6fw6q 6120 11 normal normal JJ cord-006870-f5w6fw6q 6120 12 sodium sodium NN cord-006870-f5w6fw6q 6120 13 levels level NNS cord-006870-f5w6fw6q 6120 14 and and CC cord-006870-f5w6fw6q 6120 15 with with IN cord-006870-f5w6fw6q 6120 16 no no DT cord-006870-f5w6fw6q 6120 17 neurological neurological JJ cord-006870-f5w6fw6q 6120 18 deficits deficit NNS cord-006870-f5w6fw6q 6120 19 . . . cord-006870-f5w6fw6q 6121 1 This this DT cord-006870-f5w6fw6q 6121 2 case case NN cord-006870-f5w6fw6q 6121 3 highlights highlight VBZ cord-006870-f5w6fw6q 6121 4 the the DT cord-006870-f5w6fw6q 6121 5 difficulty difficulty NN cord-006870-f5w6fw6q 6121 6 encountered encounter VBN cord-006870-f5w6fw6q 6121 7 in in IN cord-006870-f5w6fw6q 6121 8 managing manage VBG cord-006870-f5w6fw6q 6121 9 concomitant concomitant JJ cord-006870-f5w6fw6q 6121 10 cerebral cerebral JJ cord-006870-f5w6fw6q 6121 11 salt salt NN cord-006870-f5w6fw6q 6121 12 wasting wasting NN cord-006870-f5w6fw6q 6121 13 and and CC cord-006870-f5w6fw6q 6121 14 diabetes diabetes NN cord-006870-f5w6fw6q 6121 15 insipidus insipidus NN cord-006870-f5w6fw6q 6121 16 in in IN cord-006870-f5w6fw6q 6121 17 critically critically RB cord-006870-f5w6fw6q 6121 18 ill ill JJ cord-006870-f5w6fw6q 6121 19 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 6121 20 patients patient NNS cord-006870-f5w6fw6q 6121 21 and and CC cord-006870-f5w6fw6q 6121 22 the the DT cord-006870-f5w6fw6q 6121 23 need need NN cord-006870-f5w6fw6q 6121 24 to to TO cord-006870-f5w6fw6q 6121 25 for for IN cord-006870-f5w6fw6q 6121 26 a a DT cord-006870-f5w6fw6q 6121 27 high high JJ cord-006870-f5w6fw6q 6121 28 index index NN cord-006870-f5w6fw6q 6121 29 of of IN cord-006870-f5w6fw6q 6121 30 clinical clinical JJ cord-006870-f5w6fw6q 6121 31 suspicion suspicion NN cord-006870-f5w6fw6q 6121 32 , , , cord-006870-f5w6fw6q 6121 33 early early JJ cord-006870-f5w6fw6q 6121 34 intervention intervention NN cord-006870-f5w6fw6q 6121 35 and and CC cord-006870-f5w6fw6q 6121 36 close close JJ cord-006870-f5w6fw6q 6121 37 monitoring monitoring NN cord-006870-f5w6fw6q 6121 38 . . . cord-006870-f5w6fw6q 6122 1 Levetiracetam Levetiracetam NNP cord-006870-f5w6fw6q 6122 2 is be VBZ cord-006870-f5w6fw6q 6122 3 a a DT cord-006870-f5w6fw6q 6122 4 commonly commonly RB cord-006870-f5w6fw6q 6122 5 used use VBN cord-006870-f5w6fw6q 6122 6 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 6122 7 drug drug NN cord-006870-f5w6fw6q 6122 8 ( ( -LRB- cord-006870-f5w6fw6q 6122 9 AED AED NNP cord-006870-f5w6fw6q 6122 10 ) ) -RRB- cord-006870-f5w6fw6q 6122 11 used use VBD cord-006870-f5w6fw6q 6122 12 to to TO cord-006870-f5w6fw6q 6122 13 treat treat VB cord-006870-f5w6fw6q 6122 14 epilepsy epilepsy NN cord-006870-f5w6fw6q 6122 15 . . . cord-006870-f5w6fw6q 6123 1 This this DT cord-006870-f5w6fw6q 6123 2 agent agent NN cord-006870-f5w6fw6q 6123 3 was be VBD cord-006870-f5w6fw6q 6123 4 approved approve VBN cord-006870-f5w6fw6q 6123 5 by by IN cord-006870-f5w6fw6q 6123 6 the the DT cord-006870-f5w6fw6q 6123 7 FDA FDA NNP cord-006870-f5w6fw6q 6123 8 in in IN cord-006870-f5w6fw6q 6123 9 1999 1999 CD cord-006870-f5w6fw6q 6123 10 , , , cord-006870-f5w6fw6q 6123 11 is be VBZ cord-006870-f5w6fw6q 6123 12 available available JJ cord-006870-f5w6fw6q 6123 13 in in IN cord-006870-f5w6fw6q 6123 14 oral oral JJ cord-006870-f5w6fw6q 6123 15 and and CC cord-006870-f5w6fw6q 6123 16 intravenous intravenous JJ cord-006870-f5w6fw6q 6123 17 formulations formulation NNS cord-006870-f5w6fw6q 6123 18 , , , cord-006870-f5w6fw6q 6123 19 and and CC cord-006870-f5w6fw6q 6123 20 offers offer VBZ cord-006870-f5w6fw6q 6123 21 advantageous advantageous JJ cord-006870-f5w6fw6q 6123 22 pharmacokinetics pharmacokinetic NNS cord-006870-f5w6fw6q 6123 23 , , , cord-006870-f5w6fw6q 6123 24 minimal minimal JJ cord-006870-f5w6fw6q 6123 25 drug drug NN cord-006870-f5w6fw6q 6123 26 interactions interaction NNS cord-006870-f5w6fw6q 6123 27 , , , cord-006870-f5w6fw6q 6123 28 and and CC cord-006870-f5w6fw6q 6123 29 a a DT cord-006870-f5w6fw6q 6123 30 favorable favorable JJ cord-006870-f5w6fw6q 6123 31 side side NN cord-006870-f5w6fw6q 6123 32 effect effect NN cord-006870-f5w6fw6q 6123 33 profile profile NN cord-006870-f5w6fw6q 6123 34 . . . cord-006870-f5w6fw6q 6124 1 The the DT cord-006870-f5w6fw6q 6124 2 purpose purpose NN cord-006870-f5w6fw6q 6124 3 of of IN cord-006870-f5w6fw6q 6124 4 this this DT cord-006870-f5w6fw6q 6124 5 case case NN cord-006870-f5w6fw6q 6124 6 report report NN cord-006870-f5w6fw6q 6124 7 is be VBZ cord-006870-f5w6fw6q 6124 8 to to TO cord-006870-f5w6fw6q 6124 9 describe describe VB cord-006870-f5w6fw6q 6124 10 a a DT cord-006870-f5w6fw6q 6124 11 case case NN cord-006870-f5w6fw6q 6124 12 of of IN cord-006870-f5w6fw6q 6124 13 severe severe JJ cord-006870-f5w6fw6q 6124 14 , , , cord-006870-f5w6fw6q 6124 15 asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 6124 16 rhabdomyolysis rhabdomyolysis NN cord-006870-f5w6fw6q 6124 17 exacerbated exacerbate VBN cord-006870-f5w6fw6q 6124 18 by by IN cord-006870-f5w6fw6q 6124 19 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 6124 20 administration administration NN cord-006870-f5w6fw6q 6124 21 . . . cord-006870-f5w6fw6q 6125 1 The the DT cord-006870-f5w6fw6q 6125 2 medical medical JJ cord-006870-f5w6fw6q 6125 3 record record NN cord-006870-f5w6fw6q 6125 4 was be VBD cord-006870-f5w6fw6q 6125 5 reviewed review VBN cord-006870-f5w6fw6q 6125 6 and and CC cord-006870-f5w6fw6q 6125 7 data datum NNS cord-006870-f5w6fw6q 6125 8 was be VBD cord-006870-f5w6fw6q 6125 9 collected collect VBN cord-006870-f5w6fw6q 6125 10 to to TO cord-006870-f5w6fw6q 6125 11 describe describe VB cord-006870-f5w6fw6q 6125 12 a a DT cord-006870-f5w6fw6q 6125 13 case case NN cord-006870-f5w6fw6q 6125 14 with with IN cord-006870-f5w6fw6q 6125 15 a a DT cord-006870-f5w6fw6q 6125 16 pertinent pertinent JJ cord-006870-f5w6fw6q 6125 17 review review NN cord-006870-f5w6fw6q 6125 18 of of IN cord-006870-f5w6fw6q 6125 19 the the DT cord-006870-f5w6fw6q 6125 20 literature literature NN cord-006870-f5w6fw6q 6125 21 . . . cord-006870-f5w6fw6q 6126 1 A a DT cord-006870-f5w6fw6q 6126 2 43-year 43-year JJ cord-006870-f5w6fw6q 6126 3 - - HYPH cord-006870-f5w6fw6q 6126 4 old old JJ cord-006870-f5w6fw6q 6126 5 African african JJ cord-006870-f5w6fw6q 6126 6 - - HYPH cord-006870-f5w6fw6q 6126 7 American american JJ cord-006870-f5w6fw6q 6126 8 male male NN cord-006870-f5w6fw6q 6126 9 with with IN cord-006870-f5w6fw6q 6126 10 a a DT cord-006870-f5w6fw6q 6126 11 history history NN cord-006870-f5w6fw6q 6126 12 of of IN cord-006870-f5w6fw6q 6126 13 hypertension hypertension NN cord-006870-f5w6fw6q 6126 14 presented present VBN cord-006870-f5w6fw6q 6126 15 to to IN cord-006870-f5w6fw6q 6126 16 the the DT cord-006870-f5w6fw6q 6126 17 emergency emergency NN cord-006870-f5w6fw6q 6126 18 department department NN cord-006870-f5w6fw6q 6126 19 following follow VBG cord-006870-f5w6fw6q 6126 20 a a DT cord-006870-f5w6fw6q 6126 21 tonic tonic JJ cord-006870-f5w6fw6q 6126 22 - - HYPH cord-006870-f5w6fw6q 6126 23 clonic clonic JJ cord-006870-f5w6fw6q 6126 24 seizure seizure NN cord-006870-f5w6fw6q 6126 25 . . . cord-006870-f5w6fw6q 6127 1 Baseline baseline JJ cord-006870-f5w6fw6q 6127 2 labs lab NNS cord-006870-f5w6fw6q 6127 3 were be VBD cord-006870-f5w6fw6q 6127 4 drawn draw VBN cord-006870-f5w6fw6q 6127 5 and and CC cord-006870-f5w6fw6q 6127 6 revealed reveal VBN cord-006870-f5w6fw6q 6127 7 a a DT cord-006870-f5w6fw6q 6127 8 CK CK NNP cord-006870-f5w6fw6q 6127 9 level level NN cord-006870-f5w6fw6q 6127 10 of of IN cord-006870-f5w6fw6q 6127 11 1,226 1,226 CD cord-006870-f5w6fw6q 6127 12 IU IU NNP cord-006870-f5w6fw6q 6127 13 / / SYM cord-006870-f5w6fw6q 6127 14 L L NNP cord-006870-f5w6fw6q 6127 15 , , , cord-006870-f5w6fw6q 6127 16 negative negative JJ cord-006870-f5w6fw6q 6127 17 urine urine NN cord-006870-f5w6fw6q 6127 18 myoglobin myoglobin NN cord-006870-f5w6fw6q 6127 19 and and CC cord-006870-f5w6fw6q 6127 20 normal normal JJ cord-006870-f5w6fw6q 6127 21 renal renal JJ cord-006870-f5w6fw6q 6127 22 function function NN cord-006870-f5w6fw6q 6127 23 . . . cord-006870-f5w6fw6q 6128 1 Levetiracetam Levetiracetam NNP cord-006870-f5w6fw6q 6128 2 therapy therapy NN cord-006870-f5w6fw6q 6128 3 was be VBD cord-006870-f5w6fw6q 6128 4 initiated initiate VBN cord-006870-f5w6fw6q 6128 5 and and CC cord-006870-f5w6fw6q 6128 6 no no DT cord-006870-f5w6fw6q 6128 7 further further JJ cord-006870-f5w6fw6q 6128 8 seizures seizure NNS cord-006870-f5w6fw6q 6128 9 were be VBD cord-006870-f5w6fw6q 6128 10 noted note VBN cord-006870-f5w6fw6q 6128 11 . . . cord-006870-f5w6fw6q 6129 1 The the DT cord-006870-f5w6fw6q 6129 2 patient patient NN cord-006870-f5w6fw6q 6129 3 's 's POS cord-006870-f5w6fw6q 6129 4 CK CK NNP cord-006870-f5w6fw6q 6129 5 continued continue VBD cord-006870-f5w6fw6q 6129 6 to to TO cord-006870-f5w6fw6q 6129 7 trend trend VB cord-006870-f5w6fw6q 6129 8 up up RP cord-006870-f5w6fw6q 6129 9 throughout throughout IN cord-006870-f5w6fw6q 6129 10 his -PRON- PRP$ cord-006870-f5w6fw6q 6129 11 stay stay NN cord-006870-f5w6fw6q 6129 12 despite despite IN cord-006870-f5w6fw6q 6129 13 aggressive aggressive JJ cord-006870-f5w6fw6q 6129 14 fluid fluid JJ cord-006870-f5w6fw6q 6129 15 resuscitation resuscitation NN cord-006870-f5w6fw6q 6129 16 with with IN cord-006870-f5w6fw6q 6129 17 a a DT cord-006870-f5w6fw6q 6129 18 positive positive JJ cord-006870-f5w6fw6q 6129 19 myoglobin myoglobin NN cord-006870-f5w6fw6q 6129 20 on on IN cord-006870-f5w6fw6q 6129 21 hospital hospital NN cord-006870-f5w6fw6q 6129 22 day day NN cord-006870-f5w6fw6q 6129 23 2 2 CD cord-006870-f5w6fw6q 6129 24 . . . cord-006870-f5w6fw6q 6130 1 The the DT cord-006870-f5w6fw6q 6130 2 CK CK NNP cord-006870-f5w6fw6q 6130 3 reached reach VBD cord-006870-f5w6fw6q 6130 4 a a DT cord-006870-f5w6fw6q 6130 5 peak peak NN cord-006870-f5w6fw6q 6130 6 of of IN cord-006870-f5w6fw6q 6130 7 41,463 41,463 CD cord-006870-f5w6fw6q 6130 8 IU IU NNP cord-006870-f5w6fw6q 6130 9 / / SYM cord-006870-f5w6fw6q 6130 10 L L NNP cord-006870-f5w6fw6q 6130 11 on on IN cord-006870-f5w6fw6q 6130 12 hospital hospital NN cord-006870-f5w6fw6q 6130 13 day day NN cord-006870-f5w6fw6q 6130 14 4 4 CD cord-006870-f5w6fw6q 6130 15 . . . cord-006870-f5w6fw6q 6131 1 After after IN cord-006870-f5w6fw6q 6131 2 a a DT cord-006870-f5w6fw6q 6131 3 literature literature NN cord-006870-f5w6fw6q 6131 4 review review NN cord-006870-f5w6fw6q 6131 5 and and CC cord-006870-f5w6fw6q 6131 6 evaluation evaluation NN cord-006870-f5w6fw6q 6131 7 of of IN cord-006870-f5w6fw6q 6131 8 his -PRON- PRP$ cord-006870-f5w6fw6q 6131 9 medication medication NN cord-006870-f5w6fw6q 6131 10 list list NN cord-006870-f5w6fw6q 6131 11 , , , cord-006870-f5w6fw6q 6131 12 six six CD cord-006870-f5w6fw6q 6131 13 casereports casereport NNS cord-006870-f5w6fw6q 6131 14 were be VBD cord-006870-f5w6fw6q 6131 15 identified identify VBN cord-006870-f5w6fw6q 6131 16 linking link VBG cord-006870-f5w6fw6q 6131 17 elevated elevate VBN cord-006870-f5w6fw6q 6131 18 CK CK NNP cord-006870-f5w6fw6q 6131 19 and and CC cord-006870-f5w6fw6q 6131 20 rhabdomyolysis rhabdomyolysis NN cord-006870-f5w6fw6q 6131 21 to to IN cord-006870-f5w6fw6q 6131 22 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 6131 23 administration administration NN cord-006870-f5w6fw6q 6131 24 . . . cord-006870-f5w6fw6q 6132 1 At at IN cord-006870-f5w6fw6q 6132 2 that that DT cord-006870-f5w6fw6q 6132 3 time time NN cord-006870-f5w6fw6q 6132 4 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 6132 5 was be VBD cord-006870-f5w6fw6q 6132 6 discontinued discontinue VBN cord-006870-f5w6fw6q 6132 7 and and CC cord-006870-f5w6fw6q 6132 8 the the DT cord-006870-f5w6fw6q 6132 9 CK CK NNP cord-006870-f5w6fw6q 6132 10 rapidly rapidly RB cord-006870-f5w6fw6q 6132 11 declined decline VBD cord-006870-f5w6fw6q 6132 12 to to IN cord-006870-f5w6fw6q 6132 13 6,426 6,426 CD cord-006870-f5w6fw6q 6132 14 IU IU NNP cord-006870-f5w6fw6q 6132 15 / / SYM cord-006870-f5w6fw6q 6132 16 L L NNP cord-006870-f5w6fw6q 6132 17 on on IN cord-006870-f5w6fw6q 6132 18 hospital hospital NN cord-006870-f5w6fw6q 6132 19 day day NN cord-006870-f5w6fw6q 6132 20 6 6 CD cord-006870-f5w6fw6q 6132 21 . . . cord-006870-f5w6fw6q 6133 1 The the DT cord-006870-f5w6fw6q 6133 2 patient patient NN cord-006870-f5w6fw6q 6133 3 never never RB cord-006870-f5w6fw6q 6133 4 had have VBD cord-006870-f5w6fw6q 6133 5 muscle muscle NN cord-006870-f5w6fw6q 6133 6 pain pain NN cord-006870-f5w6fw6q 6133 7 or or CC cord-006870-f5w6fw6q 6133 8 kidney kidney NN cord-006870-f5w6fw6q 6133 9 injury injury NN cord-006870-f5w6fw6q 6133 10 and and CC cord-006870-f5w6fw6q 6133 11 was be VBD cord-006870-f5w6fw6q 6133 12 discharged discharge VBN cord-006870-f5w6fw6q 6133 13 on on IN cord-006870-f5w6fw6q 6133 14 hospital hospital NN cord-006870-f5w6fw6q 6133 15 day day NN cord-006870-f5w6fw6q 6133 16 6 6 CD cord-006870-f5w6fw6q 6133 17 . . . cord-006870-f5w6fw6q 6134 1 This this DT cord-006870-f5w6fw6q 6134 2 case case NN cord-006870-f5w6fw6q 6134 3 - - HYPH cord-006870-f5w6fw6q 6134 4 report report NN cord-006870-f5w6fw6q 6134 5 describes describe VBZ cord-006870-f5w6fw6q 6134 6 rhabdomyolysis rhabdomyolysis NN cord-006870-f5w6fw6q 6134 7 associated associate VBN cord-006870-f5w6fw6q 6134 8 with with IN cord-006870-f5w6fw6q 6134 9 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 6134 10 administration administration NN cord-006870-f5w6fw6q 6134 11 with with IN cord-006870-f5w6fw6q 6134 12 a a DT cord-006870-f5w6fw6q 6134 13 Naranjo Naranjo NNP cord-006870-f5w6fw6q 6134 14 Probability Probability NNP cord-006870-f5w6fw6q 6134 15 Scale Scale NNP cord-006870-f5w6fw6q 6134 16 score score NN cord-006870-f5w6fw6q 6134 17 of of IN cord-006870-f5w6fw6q 6134 18 6 6 CD cord-006870-f5w6fw6q 6134 19 indicating indicate VBG cord-006870-f5w6fw6q 6134 20 a a DT cord-006870-f5w6fw6q 6134 21 probable probable JJ cord-006870-f5w6fw6q 6134 22 adverse adverse JJ cord-006870-f5w6fw6q 6134 23 drug drug NN cord-006870-f5w6fw6q 6134 24 reaction reaction NN cord-006870-f5w6fw6q 6134 25 . . . cord-006870-f5w6fw6q 6135 1 The the DT cord-006870-f5w6fw6q 6135 2 adverse adverse JJ cord-006870-f5w6fw6q 6135 3 effects effect NNS cord-006870-f5w6fw6q 6135 4 of of IN cord-006870-f5w6fw6q 6135 5 generalized generalized JJ cord-006870-f5w6fw6q 6135 6 pain pain NN cord-006870-f5w6fw6q 6135 7 and and CC cord-006870-f5w6fw6q 6135 8 neck neck NN cord-006870-f5w6fw6q 6135 9 pain pain NN cord-006870-f5w6fw6q 6135 10 are be VBP cord-006870-f5w6fw6q 6135 11 described describe VBN cord-006870-f5w6fw6q 6135 12 in in IN cord-006870-f5w6fw6q 6135 13 the the DT cord-006870-f5w6fw6q 6135 14 package package NN cord-006870-f5w6fw6q 6135 15 insert insert NN cord-006870-f5w6fw6q 6135 16 with with IN cord-006870-f5w6fw6q 6135 17 an an DT cord-006870-f5w6fw6q 6135 18 incidence incidence NN cord-006870-f5w6fw6q 6135 19 of of IN cord-006870-f5w6fw6q 6135 20 2 2 CD cord-006870-f5w6fw6q 6135 21 - - SYM cord-006870-f5w6fw6q 6135 22 8 8 CD cord-006870-f5w6fw6q 6135 23 % % NN cord-006870-f5w6fw6q 6135 24 ; ; , cord-006870-f5w6fw6q 6135 25 however however RB cord-006870-f5w6fw6q 6135 26 , , , cord-006870-f5w6fw6q 6135 27 it -PRON- PRP cord-006870-f5w6fw6q 6135 28 is be VBZ cord-006870-f5w6fw6q 6135 29 not not RB cord-006870-f5w6fw6q 6135 30 reported report VBN cord-006870-f5w6fw6q 6135 31 that that IN cord-006870-f5w6fw6q 6135 32 CK CK NNP cord-006870-f5w6fw6q 6135 33 levels level NNS cord-006870-f5w6fw6q 6135 34 were be VBD cord-006870-f5w6fw6q 6135 35 monitored monitor VBN cord-006870-f5w6fw6q 6135 36 . . . cord-006870-f5w6fw6q 6136 1 Due due IN cord-006870-f5w6fw6q 6136 2 to to IN cord-006870-f5w6fw6q 6136 3 the the DT cord-006870-f5w6fw6q 6136 4 frequent frequent JJ cord-006870-f5w6fw6q 6136 5 use use NN cord-006870-f5w6fw6q 6136 6 of of IN cord-006870-f5w6fw6q 6136 7 this this DT cord-006870-f5w6fw6q 6136 8 AED AED NNP cord-006870-f5w6fw6q 6136 9 and and CC cord-006870-f5w6fw6q 6136 10 given give VBN cord-006870-f5w6fw6q 6136 11 the the DT cord-006870-f5w6fw6q 6136 12 rare rare JJ cord-006870-f5w6fw6q 6136 13 yet yet CC cord-006870-f5w6fw6q 6136 14 serious serious JJ cord-006870-f5w6fw6q 6136 15 adverse adverse JJ cord-006870-f5w6fw6q 6136 16 effect effect NN cord-006870-f5w6fw6q 6136 17 of of IN cord-006870-f5w6fw6q 6136 18 rhabdomyolysis rhabdomyolysis NN cord-006870-f5w6fw6q 6136 19 , , , cord-006870-f5w6fw6q 6136 20 CK CK NNP cord-006870-f5w6fw6q 6136 21 levels level NNS cord-006870-f5w6fw6q 6136 22 should should MD cord-006870-f5w6fw6q 6136 23 be be VB cord-006870-f5w6fw6q 6136 24 monitored monitor VBN cord-006870-f5w6fw6q 6136 25 upon upon IN cord-006870-f5w6fw6q 6136 26 initiation initiation NN cord-006870-f5w6fw6q 6136 27 . . . cord-006870-f5w6fw6q 6137 1 Acute acute JJ cord-006870-f5w6fw6q 6137 2 Toxic toxic JJ cord-006870-f5w6fw6q 6137 3 Leukoencephalopathy Leukoencephalopathy NNP cord-006870-f5w6fw6q 6137 4 ( ( -LRB- cord-006870-f5w6fw6q 6137 5 ATL ATL NNP cord-006870-f5w6fw6q 6137 6 ) ) -RRB- cord-006870-f5w6fw6q 6137 7 is be VBZ cord-006870-f5w6fw6q 6137 8 a a DT cord-006870-f5w6fw6q 6137 9 potentially potentially RB cord-006870-f5w6fw6q 6137 10 reversible reversible JJ cord-006870-f5w6fw6q 6137 11 disturbance disturbance NN cord-006870-f5w6fw6q 6137 12 to to IN cord-006870-f5w6fw6q 6137 13 white white JJ cord-006870-f5w6fw6q 6137 14 matter matter NN cord-006870-f5w6fw6q 6137 15 caused cause VBN cord-006870-f5w6fw6q 6137 16 by by IN cord-006870-f5w6fw6q 6137 17 exposure exposure NN cord-006870-f5w6fw6q 6137 18 to to IN cord-006870-f5w6fw6q 6137 19 toxins toxin NNS cord-006870-f5w6fw6q 6137 20 . . . cord-006870-f5w6fw6q 6138 1 We -PRON- PRP cord-006870-f5w6fw6q 6138 2 report report VBP cord-006870-f5w6fw6q 6138 3 the the DT cord-006870-f5w6fw6q 6138 4 first first JJ cord-006870-f5w6fw6q 6138 5 case case NN cord-006870-f5w6fw6q 6138 6 of of IN cord-006870-f5w6fw6q 6138 7 a a DT cord-006870-f5w6fw6q 6138 8 patient patient NN cord-006870-f5w6fw6q 6138 9 with with IN cord-006870-f5w6fw6q 6138 10 ATL ATL NNP cord-006870-f5w6fw6q 6138 11 in in IN cord-006870-f5w6fw6q 6138 12 the the DT cord-006870-f5w6fw6q 6138 13 setting setting NN cord-006870-f5w6fw6q 6138 14 of of IN cord-006870-f5w6fw6q 6138 15 a a DT cord-006870-f5w6fw6q 6138 16 fentanyl fentanyl NN cord-006870-f5w6fw6q 6138 17 overdose overdose NN cord-006870-f5w6fw6q 6138 18 and and CC cord-006870-f5w6fw6q 6138 19 reviewed review VBD cord-006870-f5w6fw6q 6138 20 the the DT cord-006870-f5w6fw6q 6138 21 literature literature NN cord-006870-f5w6fw6q 6138 22 . . . cord-006870-f5w6fw6q 6139 1 A a DT cord-006870-f5w6fw6q 6139 2 28 28 CD cord-006870-f5w6fw6q 6139 3 year year NN cord-006870-f5w6fw6q 6139 4 - - HYPH cord-006870-f5w6fw6q 6139 5 old old JJ cord-006870-f5w6fw6q 6139 6 man man NN cord-006870-f5w6fw6q 6139 7 with with IN cord-006870-f5w6fw6q 6139 8 a a DT cord-006870-f5w6fw6q 6139 9 history history NN cord-006870-f5w6fw6q 6139 10 of of IN cord-006870-f5w6fw6q 6139 11 opiate opiate JJ cord-006870-f5w6fw6q 6139 12 abuse abuse NN cord-006870-f5w6fw6q 6139 13 was be VBD cord-006870-f5w6fw6q 6139 14 found find VBN cord-006870-f5w6fw6q 6139 15 unconscious unconscious JJ cord-006870-f5w6fw6q 6139 16 , , , cord-006870-f5w6fw6q 6139 17 last last RB cord-006870-f5w6fw6q 6139 18 seen see VBN cord-006870-f5w6fw6q 6139 19 well well RB cord-006870-f5w6fw6q 6139 20 nine nine CD cord-006870-f5w6fw6q 6139 21 hours hour NNS cord-006870-f5w6fw6q 6139 22 prior prior RB cord-006870-f5w6fw6q 6139 23 . . . cord-006870-f5w6fw6q 6140 1 He -PRON- PRP cord-006870-f5w6fw6q 6140 2 was be VBD cord-006870-f5w6fw6q 6140 3 known know VBN cord-006870-f5w6fw6q 6140 4 to to TO cord-006870-f5w6fw6q 6140 5 have have VB cord-006870-f5w6fw6q 6140 6 purchased purchase VBN cord-006870-f5w6fw6q 6140 7 10 10 CD cord-006870-f5w6fw6q 6140 8 mg mg NN cord-006870-f5w6fw6q 6140 9 of of IN cord-006870-f5w6fw6q 6140 10 fentanyl fentanyl NNP cord-006870-f5w6fw6q 6140 11 that that DT cord-006870-f5w6fw6q 6140 12 day day NN cord-006870-f5w6fw6q 6140 13 . . . cord-006870-f5w6fw6q 6141 1 He -PRON- PRP cord-006870-f5w6fw6q 6141 2 was be VBD cord-006870-f5w6fw6q 6141 3 intubated intubate VBN cord-006870-f5w6fw6q 6141 4 and and CC cord-006870-f5w6fw6q 6141 5 briefly briefly RB cord-006870-f5w6fw6q 6141 6 required require VBD cord-006870-f5w6fw6q 6141 7 blood blood NN cord-006870-f5w6fw6q 6141 8 pressure pressure NN cord-006870-f5w6fw6q 6141 9 support support NN cord-006870-f5w6fw6q 6141 10 . . . cord-006870-f5w6fw6q 6142 1 He -PRON- PRP cord-006870-f5w6fw6q 6142 2 was be VBD cord-006870-f5w6fw6q 6142 3 initially initially RB cord-006870-f5w6fw6q 6142 4 hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 6142 5 and and CC cord-006870-f5w6fw6q 6142 6 suffered suffer VBD cord-006870-f5w6fw6q 6142 7 fulminant fulminant JJ cord-006870-f5w6fw6q 6142 8 liver liver NN cord-006870-f5w6fw6q 6142 9 damage damage NN cord-006870-f5w6fw6q 6142 10 , , , cord-006870-f5w6fw6q 6142 11 acute acute JJ cord-006870-f5w6fw6q 6142 12 kidney kidney NN cord-006870-f5w6fw6q 6142 13 injury injury NN cord-006870-f5w6fw6q 6142 14 , , , cord-006870-f5w6fw6q 6142 15 rhabdomyolysis rhabdomyolysis NN cord-006870-f5w6fw6q 6142 16 , , , cord-006870-f5w6fw6q 6142 17 and and CC cord-006870-f5w6fw6q 6142 18 stunned stun VBN cord-006870-f5w6fw6q 6142 19 myocardium myocardium NN cord-006870-f5w6fw6q 6142 20 . . . cord-006870-f5w6fw6q 6143 1 Comprehensive comprehensive JJ cord-006870-f5w6fw6q 6143 2 toxicology toxicology NN cord-006870-f5w6fw6q 6143 3 screen screen NN cord-006870-f5w6fw6q 6143 4 was be VBD cord-006870-f5w6fw6q 6143 5 positive positive JJ cord-006870-f5w6fw6q 6143 6 for for IN cord-006870-f5w6fw6q 6143 7 cannabis cannabis NN cord-006870-f5w6fw6q 6143 8 and and CC cord-006870-f5w6fw6q 6143 9 fentanyl fentanyl NN cord-006870-f5w6fw6q 6143 10 . . . cord-006870-f5w6fw6q 6144 1 MRI MRI NNP cord-006870-f5w6fw6q 6144 2 of of IN cord-006870-f5w6fw6q 6144 3 the the DT cord-006870-f5w6fw6q 6144 4 brain brain NN cord-006870-f5w6fw6q 6144 5 showed show VBD cord-006870-f5w6fw6q 6144 6 pronounced pronounce VBN cord-006870-f5w6fw6q 6144 7 bilateral bilateral JJ cord-006870-f5w6fw6q 6144 8 restricted restrict VBN cord-006870-f5w6fw6q 6144 9 diffusion diffusion NN cord-006870-f5w6fw6q 6144 10 in in IN cord-006870-f5w6fw6q 6144 11 the the DT cord-006870-f5w6fw6q 6144 12 high high JJ cord-006870-f5w6fw6q 6144 13 frontoparietal frontoparietal JJ cord-006870-f5w6fw6q 6144 14 subcortical subcortical JJ cord-006870-f5w6fw6q 6144 15 white white JJ cord-006870-f5w6fw6q 6144 16 matter matter NN cord-006870-f5w6fw6q 6144 17 with with IN cord-006870-f5w6fw6q 6144 18 radiographic radiographic JJ cord-006870-f5w6fw6q 6144 19 stability stability NN cord-006870-f5w6fw6q 6144 20 five five CD cord-006870-f5w6fw6q 6144 21 days day NNS cord-006870-f5w6fw6q 6144 22 later later RB cord-006870-f5w6fw6q 6144 23 . . . cord-006870-f5w6fw6q 6145 1 He -PRON- PRP cord-006870-f5w6fw6q 6145 2 remained remain VBD cord-006870-f5w6fw6q 6145 3 intubated intubated JJ cord-006870-f5w6fw6q 6145 4 and and CC cord-006870-f5w6fw6q 6145 5 neurologic neurologic JJ cord-006870-f5w6fw6q 6145 6 exam exam NN cord-006870-f5w6fw6q 6145 7 poor poor JJ cord-006870-f5w6fw6q 6145 8 with with IN cord-006870-f5w6fw6q 6145 9 fluctuating fluctuate VBG cord-006870-f5w6fw6q 6145 10 brainstem brainstem NN cord-006870-f5w6fw6q 6145 11 reflexes reflex NNS cord-006870-f5w6fw6q 6145 12 and and CC cord-006870-f5w6fw6q 6145 13 posturing posture VBG cord-006870-f5w6fw6q 6145 14 despite despite IN cord-006870-f5w6fw6q 6145 15 improvement improvement NN cord-006870-f5w6fw6q 6145 16 in in IN cord-006870-f5w6fw6q 6145 17 end end NN cord-006870-f5w6fw6q 6145 18 - - HYPH cord-006870-f5w6fw6q 6145 19 organ organ NN cord-006870-f5w6fw6q 6145 20 function function NN cord-006870-f5w6fw6q 6145 21 . . . cord-006870-f5w6fw6q 6146 1 ATL ATL NNP cord-006870-f5w6fw6q 6146 2 has have VBZ cord-006870-f5w6fw6q 6146 3 been be VBN cord-006870-f5w6fw6q 6146 4 reported report VBN cord-006870-f5w6fw6q 6146 5 in in IN cord-006870-f5w6fw6q 6146 6 a a DT cord-006870-f5w6fw6q 6146 7 19-month 19-month JJ cord-006870-f5w6fw6q 6146 8 - - HYPH cord-006870-f5w6fw6q 6146 9 old old JJ cord-006870-f5w6fw6q 6146 10 girl girl NN cord-006870-f5w6fw6q 6146 11 and and CC cord-006870-f5w6fw6q 6146 12 an an DT cord-006870-f5w6fw6q 6146 13 85-year 85-year JJ cord-006870-f5w6fw6q 6146 14 - - HYPH cord-006870-f5w6fw6q 6146 15 old old JJ cord-006870-f5w6fw6q 6146 16 man man NN cord-006870-f5w6fw6q 6146 17 with with IN cord-006870-f5w6fw6q 6146 18 exposure exposure NN cord-006870-f5w6fw6q 6146 19 to to IN cord-006870-f5w6fw6q 6146 20 transdermal transdermal JJ cord-006870-f5w6fw6q 6146 21 fentanyl fentanyl NN cord-006870-f5w6fw6q 6146 22 , , , cord-006870-f5w6fw6q 6146 23 both both DT cord-006870-f5w6fw6q 6146 24 of of IN cord-006870-f5w6fw6q 6146 25 whom whom WP cord-006870-f5w6fw6q 6146 26 had have VBD cord-006870-f5w6fw6q 6146 27 favorable favorable JJ cord-006870-f5w6fw6q 6146 28 outcomes outcome NNS cord-006870-f5w6fw6q 6146 29 ( ( -LRB- cord-006870-f5w6fw6q 6146 30 2,3 2,3 CD cord-006870-f5w6fw6q 6146 31 ) ) -RRB- cord-006870-f5w6fw6q 6146 32 . . . cord-006870-f5w6fw6q 6147 1 One one CD cord-006870-f5w6fw6q 6147 2 case case NN cord-006870-f5w6fw6q 6147 3 has have VBZ cord-006870-f5w6fw6q 6147 4 been be VBN cord-006870-f5w6fw6q 6147 5 reported report VBN cord-006870-f5w6fw6q 6147 6 following follow VBG cord-006870-f5w6fw6q 6147 7 oral oral JJ cord-006870-f5w6fw6q 6147 8 oxycodone oxycodone NN cord-006870-f5w6fw6q 6147 9 ingestion ingestion NN cord-006870-f5w6fw6q 6147 10 ( ( -LRB- cord-006870-f5w6fw6q 6147 11 11 11 CD cord-006870-f5w6fw6q 6147 12 ) ) -RRB- cord-006870-f5w6fw6q 6147 13 . . . cord-006870-f5w6fw6q 6148 1 Of of IN cord-006870-f5w6fw6q 6148 2 27 27 CD cord-006870-f5w6fw6q 6148 3 cases case NNS cord-006870-f5w6fw6q 6148 4 of of IN cord-006870-f5w6fw6q 6148 5 ATL ATL NNP cord-006870-f5w6fw6q 6148 6 secondary secondary JJ cord-006870-f5w6fw6q 6148 7 to to IN cord-006870-f5w6fw6q 6148 8 inhaled inhale VBN cord-006870-f5w6fw6q 6148 9 heroin heroin NN cord-006870-f5w6fw6q 6148 10 , , , cord-006870-f5w6fw6q 6148 11 48 48 CD cord-006870-f5w6fw6q 6148 12 % % NN cord-006870-f5w6fw6q 6148 13 were be VBD cord-006870-f5w6fw6q 6148 14 fatal fatal JJ cord-006870-f5w6fw6q 6148 15 ( ( -LRB- cord-006870-f5w6fw6q 6148 16 5 5 CD cord-006870-f5w6fw6q 6148 17 ) ) -RRB- cord-006870-f5w6fw6q 6148 18 . . . cord-006870-f5w6fw6q 6149 1 Preferential preferential JJ cord-006870-f5w6fw6q 6149 2 white white JJ cord-006870-f5w6fw6q 6149 3 matter matter NN cord-006870-f5w6fw6q 6149 4 injury injury NN cord-006870-f5w6fw6q 6149 5 has have VBZ cord-006870-f5w6fw6q 6149 6 been be VBN cord-006870-f5w6fw6q 6149 7 seen see VBN cord-006870-f5w6fw6q 6149 8 in in IN cord-006870-f5w6fw6q 6149 9 cases case NNS cord-006870-f5w6fw6q 6149 10 of of IN cord-006870-f5w6fw6q 6149 11 hypoxic hypoxic JJ cord-006870-f5w6fw6q 6149 12 ischemic ischemic JJ cord-006870-f5w6fw6q 6149 13 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6149 14 ( ( -LRB- cord-006870-f5w6fw6q 6149 15 HIE HIE NNP cord-006870-f5w6fw6q 6149 16 ) ) -RRB- cord-006870-f5w6fw6q 6149 17 ( ( -LRB- cord-006870-f5w6fw6q 6149 18 7,10 7,10 RB cord-006870-f5w6fw6q 6149 19 ) ) -RRB- cord-006870-f5w6fw6q 6149 20 . . . cord-006870-f5w6fw6q 6150 1 It -PRON- PRP cord-006870-f5w6fw6q 6150 2 was be VBD cord-006870-f5w6fw6q 6150 3 initially initially RB cord-006870-f5w6fw6q 6150 4 thought think VBN cord-006870-f5w6fw6q 6150 5 to to TO cord-006870-f5w6fw6q 6150 6 be be VB cord-006870-f5w6fw6q 6150 7 secondary secondary JJ cord-006870-f5w6fw6q 6150 8 to to IN cord-006870-f5w6fw6q 6150 9 Wallerian wallerian JJ cord-006870-f5w6fw6q 6150 10 degeneration degeneration NN cord-006870-f5w6fw6q 6150 11 following follow VBG cord-006870-f5w6fw6q 6150 12 grey grey JJ cord-006870-f5w6fw6q 6150 13 matter matter NN cord-006870-f5w6fw6q 6150 14 damage damage NN cord-006870-f5w6fw6q 6150 15 , , , cord-006870-f5w6fw6q 6150 16 but but CC cord-006870-f5w6fw6q 6150 17 post post JJ cord-006870-f5w6fw6q 6150 18 - - JJ cord-006870-f5w6fw6q 6150 19 mortem mortem JJ cord-006870-f5w6fw6q 6150 20 pathology pathology NN cord-006870-f5w6fw6q 6150 21 has have VBZ cord-006870-f5w6fw6q 6150 22 shown show VBN cord-006870-f5w6fw6q 6150 23 direct direct JJ cord-006870-f5w6fw6q 6150 24 insult insult NN cord-006870-f5w6fw6q 6150 25 to to IN cord-006870-f5w6fw6q 6150 26 axons axon NNS cord-006870-f5w6fw6q 6150 27 ( ( -LRB- cord-006870-f5w6fw6q 6150 28 6 6 CD cord-006870-f5w6fw6q 6150 29 ) ) -RRB- cord-006870-f5w6fw6q 6150 30 . . . cord-006870-f5w6fw6q 6151 1 ATL ATL NNP cord-006870-f5w6fw6q 6151 2 has have VBZ cord-006870-f5w6fw6q 6151 3 been be VBN cord-006870-f5w6fw6q 6151 4 reported report VBN cord-006870-f5w6fw6q 6151 5 in in IN cord-006870-f5w6fw6q 6151 6 one one CD cord-006870-f5w6fw6q 6151 7 case case NN cord-006870-f5w6fw6q 6151 8 of of IN cord-006870-f5w6fw6q 6151 9 hypoglycemic hypoglycemic JJ cord-006870-f5w6fw6q 6151 10 coma coma NN cord-006870-f5w6fw6q 6151 11 ( ( -LRB- cord-006870-f5w6fw6q 6151 12 8) 8) NN cord-006870-f5w6fw6q 6151 13 and and CC cord-006870-f5w6fw6q 6151 14 one one CD cord-006870-f5w6fw6q 6151 15 case case NN cord-006870-f5w6fw6q 6151 16 of of IN cord-006870-f5w6fw6q 6151 17 uremia uremia NN cord-006870-f5w6fw6q 6151 18 ( ( -LRB- cord-006870-f5w6fw6q 6151 19 9 9 CD cord-006870-f5w6fw6q 6151 20 ) ) -RRB- cord-006870-f5w6fw6q 6151 21 . . . cord-006870-f5w6fw6q 6152 1 It -PRON- PRP cord-006870-f5w6fw6q 6152 2 has have VBZ cord-006870-f5w6fw6q 6152 3 never never RB cord-006870-f5w6fw6q 6152 4 been be VBN cord-006870-f5w6fw6q 6152 5 reported report VBN cord-006870-f5w6fw6q 6152 6 in in IN cord-006870-f5w6fw6q 6152 7 isolated isolate VBN cord-006870-f5w6fw6q 6152 8 hepatic hepatic JJ cord-006870-f5w6fw6q 6152 9 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6152 10 , , , cord-006870-f5w6fw6q 6152 11 secondary secondary JJ cord-006870-f5w6fw6q 6152 12 to to IN cord-006870-f5w6fw6q 6152 13 seizure seizure NN cord-006870-f5w6fw6q 6152 14 , , , cord-006870-f5w6fw6q 6152 15 or or CC cord-006870-f5w6fw6q 6152 16 with with IN cord-006870-f5w6fw6q 6152 17 cannabis cannabis NN cord-006870-f5w6fw6q 6152 18 use use NN cord-006870-f5w6fw6q 6152 19 alone alone JJ cord-006870-f5w6fw6q 6152 20 . . . cord-006870-f5w6fw6q 6153 1 Based base VBN cord-006870-f5w6fw6q 6153 2 on on IN cord-006870-f5w6fw6q 6153 3 our -PRON- PRP$ cord-006870-f5w6fw6q 6153 4 review review NN cord-006870-f5w6fw6q 6153 5 of of IN cord-006870-f5w6fw6q 6153 6 the the DT cord-006870-f5w6fw6q 6153 7 literature literature NN cord-006870-f5w6fw6q 6153 8 , , , cord-006870-f5w6fw6q 6153 9 the the DT cord-006870-f5w6fw6q 6153 10 most most RBS cord-006870-f5w6fw6q 6153 11 likely likely JJ cord-006870-f5w6fw6q 6153 12 causes cause NNS cord-006870-f5w6fw6q 6153 13 of of IN cord-006870-f5w6fw6q 6153 14 this this DT cord-006870-f5w6fw6q 6153 15 patient patient NN cord-006870-f5w6fw6q 6153 16 's 's POS cord-006870-f5w6fw6q 6153 17 ATL ATL NNP cord-006870-f5w6fw6q 6153 18 are be VBP cord-006870-f5w6fw6q 6153 19 fentanyl fentanyl NN cord-006870-f5w6fw6q 6153 20 or or CC cord-006870-f5w6fw6q 6153 21 HIE HIE NNP cord-006870-f5w6fw6q 6153 22 . . . cord-006870-f5w6fw6q 6154 1 Fentanyl fentanyl NN cord-006870-f5w6fw6q 6154 2 should should MD cord-006870-f5w6fw6q 6154 3 remain remain VB cord-006870-f5w6fw6q 6154 4 on on IN cord-006870-f5w6fw6q 6154 5 the the DT cord-006870-f5w6fw6q 6154 6 differential differential NN cord-006870-f5w6fw6q 6154 7 as as IN cord-006870-f5w6fw6q 6154 8 a a DT cord-006870-f5w6fw6q 6154 9 previously previously RB cord-006870-f5w6fw6q 6154 10 unreported unreported JJ cord-006870-f5w6fw6q 6154 11 cause cause NN cord-006870-f5w6fw6q 6154 12 of of IN cord-006870-f5w6fw6q 6154 13 ATL ATL NNP cord-006870-f5w6fw6q 6154 14 . . . cord-006870-f5w6fw6q 6155 1 Autonomic autonomic JJ cord-006870-f5w6fw6q 6155 2 dysregulation dysregulation NN cord-006870-f5w6fw6q 6155 3 is be VBZ cord-006870-f5w6fw6q 6155 4 a a DT cord-006870-f5w6fw6q 6155 5 common common JJ cord-006870-f5w6fw6q 6155 6 complication complication NN cord-006870-f5w6fw6q 6155 7 of of IN cord-006870-f5w6fw6q 6155 8 acute acute JJ cord-006870-f5w6fw6q 6155 9 spinal spinal JJ cord-006870-f5w6fw6q 6155 10 cord cord NN cord-006870-f5w6fw6q 6155 11 injury injury NN cord-006870-f5w6fw6q 6155 12 ( ( -LRB- cord-006870-f5w6fw6q 6155 13 SCI SCI NNP cord-006870-f5w6fw6q 6155 14 ) ) -RRB- cord-006870-f5w6fw6q 6155 15 . . . cord-006870-f5w6fw6q 6156 1 Subsequent subsequent JJ cord-006870-f5w6fw6q 6156 2 hypotension hypotension NN cord-006870-f5w6fw6q 6156 3 may may MD cord-006870-f5w6fw6q 6156 4 worsen worsen VB cord-006870-f5w6fw6q 6156 5 central central JJ cord-006870-f5w6fw6q 6156 6 nervous nervous JJ cord-006870-f5w6fw6q 6156 7 system system NN cord-006870-f5w6fw6q 6156 8 injury injury NN cord-006870-f5w6fw6q 6156 9 as as RB cord-006870-f5w6fw6q 6156 10 well well RB cord-006870-f5w6fw6q 6156 11 as as IN cord-006870-f5w6fw6q 6156 12 neurologic neurologic JJ cord-006870-f5w6fw6q 6156 13 and and CC cord-006870-f5w6fw6q 6156 14 mortality mortality NN cord-006870-f5w6fw6q 6156 15 outcomes outcome NNS cord-006870-f5w6fw6q 6156 16 . . . cord-006870-f5w6fw6q 6157 1 To to TO cord-006870-f5w6fw6q 6157 2 help help VB cord-006870-f5w6fw6q 6157 3 mitigate mitigate VB cord-006870-f5w6fw6q 6157 4 this this DT cord-006870-f5w6fw6q 6157 5 occurrence occurrence NN cord-006870-f5w6fw6q 6157 6 , , , cord-006870-f5w6fw6q 6157 7 consensus consensus NN cord-006870-f5w6fw6q 6157 8 guidelines guideline NNS cord-006870-f5w6fw6q 6157 9 recommend recommend VBP cord-006870-f5w6fw6q 6157 10 maintaining maintain VBG cord-006870-f5w6fw6q 6157 11 patients patient NNS cord-006870-f5w6fw6q 6157 12 ' ' POS cord-006870-f5w6fw6q 6157 13 mean mean VB cord-006870-f5w6fw6q 6157 14 arterial arterial JJ cord-006870-f5w6fw6q 6157 15 pressure pressure NN cord-006870-f5w6fw6q 6157 16 ( ( -LRB- cord-006870-f5w6fw6q 6157 17 MAP MAP NNP cord-006870-f5w6fw6q 6157 18 ) ) -RRB- cord-006870-f5w6fw6q 6157 19 > > XX cord-006870-f5w6fw6q 6158 1 85 85 CD cord-006870-f5w6fw6q 6158 2 mmHg mmHg NNS cord-006870-f5w6fw6q 6158 3 within within IN cord-006870-f5w6fw6q 6158 4 the the DT cord-006870-f5w6fw6q 6158 5 first first JJ cord-006870-f5w6fw6q 6158 6 seven seven CD cord-006870-f5w6fw6q 6158 7 days day NNS cord-006870-f5w6fw6q 6158 8 based base VBN cord-006870-f5w6fw6q 6158 9 on on IN cord-006870-f5w6fw6q 6158 10 evidence evidence NN cord-006870-f5w6fw6q 6158 11 from from IN cord-006870-f5w6fw6q 6158 12 limited limited JJ cord-006870-f5w6fw6q 6158 13 clinical clinical JJ cord-006870-f5w6fw6q 6158 14 trials trial NNS cord-006870-f5w6fw6q 6158 15 . . . cord-006870-f5w6fw6q 6159 1 Limited limited JJ cord-006870-f5w6fw6q 6159 2 data data NN cord-006870-f5w6fw6q 6159 3 exists exist VBZ cord-006870-f5w6fw6q 6159 4 describing describe VBG cord-006870-f5w6fw6q 6159 5 the the DT cord-006870-f5w6fw6q 6159 6 use use NN cord-006870-f5w6fw6q 6159 7 of of IN cord-006870-f5w6fw6q 6159 8 midodrine midodrine NNP cord-006870-f5w6fw6q 6159 9 , , , cord-006870-f5w6fw6q 6159 10 an an DT cord-006870-f5w6fw6q 6159 11 alpha-1 alpha-1 NNP cord-006870-f5w6fw6q 6159 12 agonist agonist NN cord-006870-f5w6fw6q 6159 13 and and CC cord-006870-f5w6fw6q 6159 14 the the DT cord-006870-f5w6fw6q 6159 15 previously previously RB cord-006870-f5w6fw6q 6159 16 only only RB cord-006870-f5w6fw6q 6159 17 available available JJ cord-006870-f5w6fw6q 6159 18 enteral enteral JJ cord-006870-f5w6fw6q 6159 19 vasopressor vasopressor NN cord-006870-f5w6fw6q 6159 20 , , , cord-006870-f5w6fw6q 6159 21 for for IN cord-006870-f5w6fw6q 6159 22 blood blood NN cord-006870-f5w6fw6q 6159 23 pressure pressure NN cord-006870-f5w6fw6q 6159 24 ( ( -LRB- cord-006870-f5w6fw6q 6159 25 BP BP NNP cord-006870-f5w6fw6q 6159 26 ) ) -RRB- cord-006870-f5w6fw6q 6159 27 augmentation augmentation NN cord-006870-f5w6fw6q 6159 28 in in IN cord-006870-f5w6fw6q 6159 29 this this DT cord-006870-f5w6fw6q 6159 30 setting setting NN cord-006870-f5w6fw6q 6159 31 . . . cord-006870-f5w6fw6q 6160 1 The the DT cord-006870-f5w6fw6q 6160 2 use use NN cord-006870-f5w6fw6q 6160 3 of of IN cord-006870-f5w6fw6q 6160 4 midodrine midodrine NN cord-006870-f5w6fw6q 6160 5 is be VBZ cord-006870-f5w6fw6q 6160 6 limited limit VBN cord-006870-f5w6fw6q 6160 7 by by IN cord-006870-f5w6fw6q 6160 8 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 6160 9 side side NN cord-006870-f5w6fw6q 6160 10 effects effect NNS cord-006870-f5w6fw6q 6160 11 such such JJ cord-006870-f5w6fw6q 6160 12 as as IN cord-006870-f5w6fw6q 6160 13 bradycardia bradycardia NN cord-006870-f5w6fw6q 6160 14 . . . cord-006870-f5w6fw6q 6161 1 Droxidopa Droxidopa NNP cord-006870-f5w6fw6q 6161 2 , , , cord-006870-f5w6fw6q 6161 3 a a DT cord-006870-f5w6fw6q 6161 4 novel novel JJ cord-006870-f5w6fw6q 6161 5 enteral enteral NN cord-006870-f5w6fw6q 6161 6 precursor precursor NN cord-006870-f5w6fw6q 6161 7 of of IN cord-006870-f5w6fw6q 6161 8 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 6161 9 that that WDT cord-006870-f5w6fw6q 6161 10 works work VBZ cord-006870-f5w6fw6q 6161 11 independently independently RB cord-006870-f5w6fw6q 6161 12 of of IN cord-006870-f5w6fw6q 6161 13 the the DT cord-006870-f5w6fw6q 6161 14 central central JJ cord-006870-f5w6fw6q 6161 15 nervous nervous JJ cord-006870-f5w6fw6q 6161 16 system system NN cord-006870-f5w6fw6q 6161 17 , , , cord-006870-f5w6fw6q 6161 18 may may MD cord-006870-f5w6fw6q 6161 19 serve serve VB cord-006870-f5w6fw6q 6161 20 a a DT cord-006870-f5w6fw6q 6161 21 role role NN cord-006870-f5w6fw6q 6161 22 in in IN cord-006870-f5w6fw6q 6161 23 sustaining sustain VBG cord-006870-f5w6fw6q 6161 24 MAP map NN cord-006870-f5w6fw6q 6161 25 in in IN cord-006870-f5w6fw6q 6161 26 acute acute JJ cord-006870-f5w6fw6q 6161 27 SCI SCI NNP cord-006870-f5w6fw6q 6161 28 . . . cord-006870-f5w6fw6q 6162 1 We -PRON- PRP cord-006870-f5w6fw6q 6162 2 describe describe VBP cord-006870-f5w6fw6q 6162 3 a a DT cord-006870-f5w6fw6q 6162 4 novel novel JJ cord-006870-f5w6fw6q 6162 5 case case NN cord-006870-f5w6fw6q 6162 6 of of IN cord-006870-f5w6fw6q 6162 7 droxidopa droxidopa NN cord-006870-f5w6fw6q 6162 8 use use VBP cord-006870-f5w6fw6q 6162 9 in in IN cord-006870-f5w6fw6q 6162 10 a a DT cord-006870-f5w6fw6q 6162 11 64-year 64-year JJ cord-006870-f5w6fw6q 6162 12 old old JJ cord-006870-f5w6fw6q 6162 13 male male NN cord-006870-f5w6fw6q 6162 14 who who WP cord-006870-f5w6fw6q 6162 15 sustained sustain VBD cord-006870-f5w6fw6q 6162 16 a a DT cord-006870-f5w6fw6q 6162 17 spinal spinal JJ cord-006870-f5w6fw6q 6162 18 cord cord NN cord-006870-f5w6fw6q 6162 19 contusion contusion NN cord-006870-f5w6fw6q 6162 20 secondary secondary JJ cord-006870-f5w6fw6q 6162 21 to to IN cord-006870-f5w6fw6q 6162 22 severe severe JJ cord-006870-f5w6fw6q 6162 23 stenosis stenosis NN cord-006870-f5w6fw6q 6162 24 at at IN cord-006870-f5w6fw6q 6162 25 the the DT cord-006870-f5w6fw6q 6162 26 fourth fourth JJ cord-006870-f5w6fw6q 6162 27 cervical cervical JJ cord-006870-f5w6fw6q 6162 28 vertebrae vertebrae NN cord-006870-f5w6fw6q 6162 29 following follow VBG cord-006870-f5w6fw6q 6162 30 a a DT cord-006870-f5w6fw6q 6162 31 ten ten CD cord-006870-f5w6fw6q 6162 32 - - HYPH cord-006870-f5w6fw6q 6162 33 foot foot NN cord-006870-f5w6fw6q 6162 34 fall fall NN cord-006870-f5w6fw6q 6162 35 . . . cord-006870-f5w6fw6q 6163 1 Droxidopa Droxidopa NNP cord-006870-f5w6fw6q 6163 2 was be VBD cord-006870-f5w6fw6q 6163 3 used use VBN cord-006870-f5w6fw6q 6163 4 to to TO cord-006870-f5w6fw6q 6163 5 facilitate facilitate VB cord-006870-f5w6fw6q 6163 6 vasopressor vasopressor NN cord-006870-f5w6fw6q 6163 7 wean wean NN cord-006870-f5w6fw6q 6163 8 in in IN cord-006870-f5w6fw6q 6163 9 the the DT cord-006870-f5w6fw6q 6163 10 setting setting NN cord-006870-f5w6fw6q 6163 11 of of IN cord-006870-f5w6fw6q 6163 12 neurogenic neurogenic JJ cord-006870-f5w6fw6q 6163 13 shock shock NN cord-006870-f5w6fw6q 6163 14 as as IN cord-006870-f5w6fw6q 6163 15 a a DT cord-006870-f5w6fw6q 6163 16 complication complication NN cord-006870-f5w6fw6q 6163 17 of of IN cord-006870-f5w6fw6q 6163 18 acute acute JJ cord-006870-f5w6fw6q 6163 19 spinal spinal JJ cord-006870-f5w6fw6q 6163 20 cord cord NN cord-006870-f5w6fw6q 6163 21 injury injury NN cord-006870-f5w6fw6q 6163 22 . . . cord-006870-f5w6fw6q 6164 1 To to TO cord-006870-f5w6fw6q 6164 2 sustain sustain VB cord-006870-f5w6fw6q 6164 3 adequate adequate JJ cord-006870-f5w6fw6q 6164 4 CNS cns NN cord-006870-f5w6fw6q 6164 5 perfusion perfusion NN cord-006870-f5w6fw6q 6164 6 ( ( -LRB- cord-006870-f5w6fw6q 6164 7 MAP MAP NNP cord-006870-f5w6fw6q 6164 8 goal goal NN cord-006870-f5w6fw6q 6165 1 > > XX cord-006870-f5w6fw6q 6165 2 65 65 CD cord-006870-f5w6fw6q 6165 3 - - SYM cord-006870-f5w6fw6q 6165 4 85 85 CD cord-006870-f5w6fw6q 6165 5 mmHg mmHg NNS cord-006870-f5w6fw6q 6165 6 ) ) -RRB- cord-006870-f5w6fw6q 6165 7 and and CC cord-006870-f5w6fw6q 6165 8 facilitate facilitate VB cord-006870-f5w6fw6q 6165 9 patient patient JJ cord-006870-f5w6fw6q 6165 10 transfer transfer NN cord-006870-f5w6fw6q 6165 11 to to IN cord-006870-f5w6fw6q 6165 12 a a DT cord-006870-f5w6fw6q 6165 13 lower low JJR cord-006870-f5w6fw6q 6165 14 level level NN cord-006870-f5w6fw6q 6165 15 of of IN cord-006870-f5w6fw6q 6165 16 care care NN cord-006870-f5w6fw6q 6165 17 , , , cord-006870-f5w6fw6q 6166 1 droxidopa droxidopa NNP cord-006870-f5w6fw6q 6166 2 100 100 CD cord-006870-f5w6fw6q 6166 3 mg mg NNP cord-006870-f5w6fw6q 6166 4 three three CD cord-006870-f5w6fw6q 6166 5 times time NNS cord-006870-f5w6fw6q 6166 6 daily daily RB cord-006870-f5w6fw6q 6166 7 was be VBD cord-006870-f5w6fw6q 6166 8 initiated initiate VBN cord-006870-f5w6fw6q 6166 9 after after IN cord-006870-f5w6fw6q 6166 10 five five CD cord-006870-f5w6fw6q 6166 11 days day NNS cord-006870-f5w6fw6q 6166 12 of of IN cord-006870-f5w6fw6q 6166 13 continuous continuous JJ cord-006870-f5w6fw6q 6166 14 infusion infusion NN cord-006870-f5w6fw6q 6166 15 of of IN cord-006870-f5w6fw6q 6166 16 intravenous intravenous JJ cord-006870-f5w6fw6q 6166 17 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 6166 18 . . . cord-006870-f5w6fw6q 6167 1 Daily daily JJ cord-006870-f5w6fw6q 6167 2 assessments assessment NNS cord-006870-f5w6fw6q 6167 3 of of IN cord-006870-f5w6fw6q 6167 4 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 6167 5 parameters parameter NNS cord-006870-f5w6fw6q 6167 6 were be VBD cord-006870-f5w6fw6q 6167 7 performed perform VBN cord-006870-f5w6fw6q 6167 8 , , , cord-006870-f5w6fw6q 6167 9 including include VBG cord-006870-f5w6fw6q 6167 10 blood blood NN cord-006870-f5w6fw6q 6167 11 pressure pressure NN cord-006870-f5w6fw6q 6167 12 , , , cord-006870-f5w6fw6q 6167 13 heart heart NN cord-006870-f5w6fw6q 6167 14 rate rate NN cord-006870-f5w6fw6q 6167 15 , , , cord-006870-f5w6fw6q 6167 16 MAP MAP NNP cord-006870-f5w6fw6q 6167 17 , , , cord-006870-f5w6fw6q 6167 18 and and CC cord-006870-f5w6fw6q 6167 19 an an DT cord-006870-f5w6fw6q 6167 20 electrocardiogram electrocardiogram NN cord-006870-f5w6fw6q 6167 21 . . . cord-006870-f5w6fw6q 6168 1 Successful successful JJ cord-006870-f5w6fw6q 6168 2 wean wean NN cord-006870-f5w6fw6q 6168 3 of of IN cord-006870-f5w6fw6q 6168 4 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 6168 5 was be VBD cord-006870-f5w6fw6q 6168 6 achieved achieve VBN cord-006870-f5w6fw6q 6168 7 within within IN cord-006870-f5w6fw6q 6168 8 24 24 CD cord-006870-f5w6fw6q 6168 9 hours hour NNS cord-006870-f5w6fw6q 6168 10 of of IN cord-006870-f5w6fw6q 6168 11 droxidopa droxidopa NN cord-006870-f5w6fw6q 6168 12 initiation initiation NN cord-006870-f5w6fw6q 6168 13 , , , cord-006870-f5w6fw6q 6168 14 with with IN cord-006870-f5w6fw6q 6168 15 an an DT cord-006870-f5w6fw6q 6168 16 average average JJ cord-006870-f5w6fw6q 6168 17 MAP map NN cord-006870-f5w6fw6q 6168 18 sustained sustain VBN cord-006870-f5w6fw6q 6168 19 above above IN cord-006870-f5w6fw6q 6168 20 65 65 CD cord-006870-f5w6fw6q 6168 21 mmHg mmHg NNS cord-006870-f5w6fw6q 6168 22 . . . cord-006870-f5w6fw6q 6169 1 The the DT cord-006870-f5w6fw6q 6169 2 patient patient NN cord-006870-f5w6fw6q 6169 3 was be VBD cord-006870-f5w6fw6q 6169 4 transferred transfer VBN cord-006870-f5w6fw6q 6169 5 to to IN cord-006870-f5w6fw6q 6169 6 a a DT cord-006870-f5w6fw6q 6169 7 lower low JJR cord-006870-f5w6fw6q 6169 8 level level NN cord-006870-f5w6fw6q 6169 9 of of IN cord-006870-f5w6fw6q 6169 10 care care NN cord-006870-f5w6fw6q 6169 11 within within IN cord-006870-f5w6fw6q 6169 12 72 72 CD cord-006870-f5w6fw6q 6169 13 hours hour NNS cord-006870-f5w6fw6q 6169 14 of of IN cord-006870-f5w6fw6q 6169 15 droxidopa droxidopa NN cord-006870-f5w6fw6q 6169 16 initiation initiation NN cord-006870-f5w6fw6q 6169 17 . . . cord-006870-f5w6fw6q 6170 1 No no DT cord-006870-f5w6fw6q 6170 2 cardiovascular cardiovascular JJ cord-006870-f5w6fw6q 6170 3 side side NN cord-006870-f5w6fw6q 6170 4 effects effect NNS cord-006870-f5w6fw6q 6170 5 were be VBD cord-006870-f5w6fw6q 6170 6 observed observe VBN cord-006870-f5w6fw6q 6170 7 . . . cord-006870-f5w6fw6q 6171 1 Droxidopa Droxidopa NNP cord-006870-f5w6fw6q 6171 2 was be VBD cord-006870-f5w6fw6q 6171 3 well well RB cord-006870-f5w6fw6q 6171 4 tolerated tolerate VBN cord-006870-f5w6fw6q 6171 5 and and CC cord-006870-f5w6fw6q 6171 6 facilitated facilitate VBN cord-006870-f5w6fw6q 6171 7 transition transition NN cord-006870-f5w6fw6q 6171 8 from from IN cord-006870-f5w6fw6q 6171 9 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 6171 10 infusion infusion NN cord-006870-f5w6fw6q 6171 11 to to IN cord-006870-f5w6fw6q 6171 12 an an DT cord-006870-f5w6fw6q 6171 13 enteral enteral JJ cord-006870-f5w6fw6q 6171 14 option option NN cord-006870-f5w6fw6q 6171 15 . . . cord-006870-f5w6fw6q 6172 1 Droxidopa Droxidopa NNP cord-006870-f5w6fw6q 6172 2 may may MD cord-006870-f5w6fw6q 6172 3 be be VB cord-006870-f5w6fw6q 6172 4 a a DT cord-006870-f5w6fw6q 6172 5 viable viable JJ cord-006870-f5w6fw6q 6172 6 option option NN cord-006870-f5w6fw6q 6172 7 in in IN cord-006870-f5w6fw6q 6172 8 stable stable JJ cord-006870-f5w6fw6q 6172 9 neurocritical neurocritical JJ cord-006870-f5w6fw6q 6172 10 care care NN cord-006870-f5w6fw6q 6172 11 patients patient NNS cord-006870-f5w6fw6q 6172 12 who who WP cord-006870-f5w6fw6q 6172 13 require require VBP cord-006870-f5w6fw6q 6172 14 vasopressors vasopressor NNS cord-006870-f5w6fw6q 6172 15 to to TO cord-006870-f5w6fw6q 6172 16 sustain sustain VB cord-006870-f5w6fw6q 6172 17 adequate adequate JJ cord-006870-f5w6fw6q 6172 18 CNS CNS NNP cord-006870-f5w6fw6q 6172 19 perfusion perfusion NN cord-006870-f5w6fw6q 6172 20 . . . cord-006870-f5w6fw6q 6173 1 Traumatic traumatic JJ cord-006870-f5w6fw6q 6173 2 brain brain NN cord-006870-f5w6fw6q 6173 3 injury injury NN cord-006870-f5w6fw6q 6173 4 is be VBZ cord-006870-f5w6fw6q 6173 5 acute acute JJ cord-006870-f5w6fw6q 6173 6 and and CC cord-006870-f5w6fw6q 6173 7 sometimes sometimes RB cord-006870-f5w6fw6q 6173 8 rapidly rapidly RB cord-006870-f5w6fw6q 6173 9 aggravated aggravate VBN cord-006870-f5w6fw6q 6173 10 during during IN cord-006870-f5w6fw6q 6173 11 or or CC cord-006870-f5w6fw6q 6173 12 after after IN cord-006870-f5w6fw6q 6173 13 surgical surgical JJ cord-006870-f5w6fw6q 6173 14 treatment treatment NN cord-006870-f5w6fw6q 6173 15 . . . cord-006870-f5w6fw6q 6174 1 Imaging imaging NN cord-006870-f5w6fw6q 6174 2 study study NN cord-006870-f5w6fw6q 6174 3 is be VBZ cord-006870-f5w6fw6q 6174 4 most most RBS cord-006870-f5w6fw6q 6174 5 important important JJ cord-006870-f5w6fw6q 6174 6 and and CC cord-006870-f5w6fw6q 6174 7 Computed computed JJ cord-006870-f5w6fw6q 6174 8 Tomography Tomography NNP cord-006870-f5w6fw6q 6174 9 ( ( -LRB- cord-006870-f5w6fw6q 6174 10 CT CT NNP cord-006870-f5w6fw6q 6174 11 ) ) -RRB- cord-006870-f5w6fw6q 6174 12 is be VBZ cord-006870-f5w6fw6q 6174 13 the the DT cord-006870-f5w6fw6q 6174 14 golden golden JJ cord-006870-f5w6fw6q 6174 15 standard standard NN cord-006870-f5w6fw6q 6174 16 in in IN cord-006870-f5w6fw6q 6174 17 TBI TBI NNP cord-006870-f5w6fw6q 6174 18 . . . cord-006870-f5w6fw6q 6175 1 However however RB cord-006870-f5w6fw6q 6175 2 the the DT cord-006870-f5w6fw6q 6175 3 patient patient NN cord-006870-f5w6fw6q 6175 4 should should MD cord-006870-f5w6fw6q 6175 5 be be VB cord-006870-f5w6fw6q 6175 6 transfer transfer NN cord-006870-f5w6fw6q 6175 7 to to IN cord-006870-f5w6fw6q 6175 8 CT CT NNP cord-006870-f5w6fw6q 6175 9 room room NN cord-006870-f5w6fw6q 6175 10 or or CC cord-006870-f5w6fw6q 6175 11 relatively relatively RB cord-006870-f5w6fw6q 6175 12 high high JJ cord-006870-f5w6fw6q 6175 13 cost cost NN cord-006870-f5w6fw6q 6175 14 mobile mobile JJ cord-006870-f5w6fw6q 6175 15 CT CT NNP cord-006870-f5w6fw6q 6175 16 scanner scanner NN cord-006870-f5w6fw6q 6175 17 may may MD cord-006870-f5w6fw6q 6175 18 be be VB cord-006870-f5w6fw6q 6175 19 used use VBN cord-006870-f5w6fw6q 6175 20 . . . cord-006870-f5w6fw6q 6176 1 Ultrasound ultrasound NN cord-006870-f5w6fw6q 6176 2 is be VBZ cord-006870-f5w6fw6q 6176 3 not not RB cord-006870-f5w6fw6q 6176 4 expensive expensive JJ cord-006870-f5w6fw6q 6176 5 and and CC cord-006870-f5w6fw6q 6176 6 also also RB cord-006870-f5w6fw6q 6176 7 does do VBZ cord-006870-f5w6fw6q 6176 8 not not RB cord-006870-f5w6fw6q 6176 9 produce produce VB cord-006870-f5w6fw6q 6176 10 radiation radiation NN cord-006870-f5w6fw6q 6176 11 exposure exposure NN cord-006870-f5w6fw6q 6176 12 . . . cord-006870-f5w6fw6q 6177 1 We -PRON- PRP cord-006870-f5w6fw6q 6177 2 studied study VBD cord-006870-f5w6fw6q 6177 3 the the DT cord-006870-f5w6fw6q 6177 4 effectiveness effectiveness NN cord-006870-f5w6fw6q 6177 5 and and CC cord-006870-f5w6fw6q 6177 6 advantages advantage NNS cord-006870-f5w6fw6q 6177 7 of of IN cord-006870-f5w6fw6q 6177 8 intra intra JJ cord-006870-f5w6fw6q 6177 9 - - JJ cord-006870-f5w6fw6q 6177 10 operative operative JJ cord-006870-f5w6fw6q 6177 11 ultrasound ultrasound NN cord-006870-f5w6fw6q 6177 12 examination examination NN cord-006870-f5w6fw6q 6177 13 in in IN cord-006870-f5w6fw6q 6177 14 traumatic traumatic JJ cord-006870-f5w6fw6q 6177 15 brain brain NN cord-006870-f5w6fw6q 6177 16 injury injury NN cord-006870-f5w6fw6q 6177 17 patients patient NNS cord-006870-f5w6fw6q 6178 1 Intra intra JJ cord-006870-f5w6fw6q 6178 2 - - JJ cord-006870-f5w6fw6q 6178 3 operative operative JJ cord-006870-f5w6fw6q 6178 4 ultrasound ultrasound NN cord-006870-f5w6fw6q 6178 5 was be VBD cord-006870-f5w6fw6q 6178 6 used use VBN cord-006870-f5w6fw6q 6178 7 after after IN cord-006870-f5w6fw6q 6178 8 decompression decompression NN cord-006870-f5w6fw6q 6178 9 of of IN cord-006870-f5w6fw6q 6178 10 injured injured JJ cord-006870-f5w6fw6q 6178 11 brain brain NN cord-006870-f5w6fw6q 6178 12 from from IN cord-006870-f5w6fw6q 6178 13 June June NNP cord-006870-f5w6fw6q 6178 14 2016 2016 CD cord-006870-f5w6fw6q 6178 15 to to IN cord-006870-f5w6fw6q 6178 16 April April NNP cord-006870-f5w6fw6q 6178 17 2017 2017 CD cord-006870-f5w6fw6q 6178 18 . . . cord-006870-f5w6fw6q 6179 1 The the DT cord-006870-f5w6fw6q 6179 2 Ultrasound Ultrasound NNP cord-006870-f5w6fw6q 6179 3 device device NN cord-006870-f5w6fw6q 6179 4 was be VBD cord-006870-f5w6fw6q 6179 5 the the DT cord-006870-f5w6fw6q 6179 6 Affiniti Affiniti NNP cord-006870-f5w6fw6q 6179 7 50 50 CD cord-006870-f5w6fw6q 6180 1 ( ( -LRB- cord-006870-f5w6fw6q 6180 2 Philips Philips NNP cord-006870-f5w6fw6q 6180 3 Ultrasound Ultrasound NNP cord-006870-f5w6fw6q 6180 4 Inc Inc NNP cord-006870-f5w6fw6q 6180 5 , , , cord-006870-f5w6fw6q 6180 6 USA USA NNP cord-006870-f5w6fw6q 6180 7 ) ) -RRB- cord-006870-f5w6fw6q 6180 8 and and CC cord-006870-f5w6fw6q 6180 9 2.5 2.5 CD cord-006870-f5w6fw6q 6180 10 Mhz Mhz NNP cord-006870-f5w6fw6q 6180 11 transducer transducer NN cord-006870-f5w6fw6q 6180 12 was be VBD cord-006870-f5w6fw6q 6180 13 used use VBN cord-006870-f5w6fw6q 6180 14 . . . cord-006870-f5w6fw6q 6181 1 The the DT cord-006870-f5w6fw6q 6181 2 transducer transducer NN cord-006870-f5w6fw6q 6181 3 was be VBD cord-006870-f5w6fw6q 6181 4 covered cover VBN cord-006870-f5w6fw6q 6181 5 by by IN cord-006870-f5w6fw6q 6181 6 thin thin JJ cord-006870-f5w6fw6q 6181 7 transparent transparent JJ cord-006870-f5w6fw6q 6181 8 sterilized sterilize VBN cord-006870-f5w6fw6q 6181 9 vinyl vinyl NN cord-006870-f5w6fw6q 6181 10 with with IN cord-006870-f5w6fw6q 6181 11 ultrasonic ultrasonic JJ cord-006870-f5w6fw6q 6181 12 gel gel NN cord-006870-f5w6fw6q 6181 13 with with IN cord-006870-f5w6fw6q 6181 14 aseptic aseptic JJ cord-006870-f5w6fw6q 6181 15 manner manner NN cord-006870-f5w6fw6q 6181 16 . . . cord-006870-f5w6fw6q 6182 1 To to TO cord-006870-f5w6fw6q 6182 2 protect protect VB cord-006870-f5w6fw6q 6182 3 brain brain NN cord-006870-f5w6fw6q 6182 4 injury injury NN cord-006870-f5w6fw6q 6182 5 by by IN cord-006870-f5w6fw6q 6182 6 the the DT cord-006870-f5w6fw6q 6182 7 ultrasonic ultrasonic JJ cord-006870-f5w6fw6q 6182 8 probe probe NN cord-006870-f5w6fw6q 6182 9 , , , cord-006870-f5w6fw6q 6182 10 a a DT cord-006870-f5w6fw6q 6182 11 saline saline NN cord-006870-f5w6fw6q 6182 12 soaked soak VBN cord-006870-f5w6fw6q 6182 13 gauze gauze NN cord-006870-f5w6fw6q 6182 14 was be VBD cord-006870-f5w6fw6q 6182 15 applied apply VBN cord-006870-f5w6fw6q 6182 16 on on IN cord-006870-f5w6fw6q 6182 17 the the DT cord-006870-f5w6fw6q 6182 18 cerebral cerebral JJ cord-006870-f5w6fw6q 6182 19 cortex cortex NN cord-006870-f5w6fw6q 6182 20 . . . cord-006870-f5w6fw6q 6183 1 The the DT cord-006870-f5w6fw6q 6183 2 axial axial JJ cord-006870-f5w6fw6q 6183 3 images image NNS cord-006870-f5w6fw6q 6183 4 were be VBD cord-006870-f5w6fw6q 6183 5 captured capture VBN cord-006870-f5w6fw6q 6183 6 and and CC cord-006870-f5w6fw6q 6183 7 then then RB cord-006870-f5w6fw6q 6183 8 stored store VBN cord-006870-f5w6fw6q 6183 9 in in IN cord-006870-f5w6fw6q 6183 10 PACS PACS NNP cord-006870-f5w6fw6q 6183 11 system system NN cord-006870-f5w6fw6q 6183 12 promptly promptly RB cord-006870-f5w6fw6q 6183 13 . . . cord-006870-f5w6fw6q 6184 1 Ultrasound ultrasound NN cord-006870-f5w6fw6q 6184 2 images image NNS cord-006870-f5w6fw6q 6184 3 were be VBD cord-006870-f5w6fw6q 6184 4 compared compare VBN cord-006870-f5w6fw6q 6184 5 to to IN cord-006870-f5w6fw6q 6184 6 postoperative postoperative JJ cord-006870-f5w6fw6q 6184 7 CT CT NNP cord-006870-f5w6fw6q 6184 8 scan scan NN cord-006870-f5w6fw6q 6184 9 . . . cord-006870-f5w6fw6q 6185 1 There there EX cord-006870-f5w6fw6q 6185 2 were be VBD cord-006870-f5w6fw6q 6185 3 13 13 CD cord-006870-f5w6fw6q 6185 4 male male NN cord-006870-f5w6fw6q 6185 5 and and CC cord-006870-f5w6fw6q 6185 6 2 2 CD cord-006870-f5w6fw6q 6185 7 female female JJ cord-006870-f5w6fw6q 6185 8 patients patient NNS cord-006870-f5w6fw6q 6185 9 were be VBD cord-006870-f5w6fw6q 6185 10 examined examine VBN cord-006870-f5w6fw6q 6185 11 by by IN cord-006870-f5w6fw6q 6185 12 ultrasound ultrasound NN cord-006870-f5w6fw6q 6185 13 during during IN cord-006870-f5w6fw6q 6185 14 there there RB cord-006870-f5w6fw6q 6185 15 surgery surgery NN cord-006870-f5w6fw6q 6185 16 . . . cord-006870-f5w6fw6q 6186 1 Ipsilateral Ipsilateral NNP cord-006870-f5w6fw6q 6186 2 hemisphere hemisphere NN cord-006870-f5w6fw6q 6186 3 , , , cord-006870-f5w6fw6q 6186 4 especially especially RB cord-006870-f5w6fw6q 6186 5 cortical cortical JJ cord-006870-f5w6fw6q 6186 6 layer layer NN cord-006870-f5w6fw6q 6186 7 was be VBD cord-006870-f5w6fw6q 6186 8 slightly slightly RB cord-006870-f5w6fw6q 6186 9 distorted distorted JJ cord-006870-f5w6fw6q 6186 10 to to IN cord-006870-f5w6fw6q 6186 11 identification identification NN cord-006870-f5w6fw6q 6186 12 . . . cord-006870-f5w6fw6q 6187 1 Brain brain NN cord-006870-f5w6fw6q 6187 2 stem stem NN cord-006870-f5w6fw6q 6187 3 area area NN cord-006870-f5w6fw6q 6187 4 was be VBD cord-006870-f5w6fw6q 6187 5 visible visible JJ cord-006870-f5w6fw6q 6187 6 in in IN cord-006870-f5w6fw6q 6187 7 most most JJS cord-006870-f5w6fw6q 6187 8 cases case NNS cord-006870-f5w6fw6q 6187 9 . . . cord-006870-f5w6fw6q 6188 1 Contralateral Contralateral NNP cord-006870-f5w6fw6q 6188 2 hemisphere hemisphere NN cord-006870-f5w6fw6q 6188 3 was be VBD cord-006870-f5w6fw6q 6188 4 seen see VBN cord-006870-f5w6fw6q 6188 5 in in IN cord-006870-f5w6fw6q 6188 6 unilateral unilateral JJ cord-006870-f5w6fw6q 6188 7 craniotomy craniotomy NN cord-006870-f5w6fw6q 6188 8 and and CC cord-006870-f5w6fw6q 6188 9 craniectomy craniectomy JJ cord-006870-f5w6fw6q 6188 10 cases case NNS cord-006870-f5w6fw6q 6188 11 . . . cord-006870-f5w6fw6q 6189 1 In in IN cord-006870-f5w6fw6q 6189 2 bilateral bilateral JJ cord-006870-f5w6fw6q 6189 3 craniectomy craniectomy JJ cord-006870-f5w6fw6q 6189 4 cases case NNS cord-006870-f5w6fw6q 6189 5 , , , cord-006870-f5w6fw6q 6189 6 both both DT cord-006870-f5w6fw6q 6189 7 hemispheres hemisphere NNS cord-006870-f5w6fw6q 6189 8 were be VBD cord-006870-f5w6fw6q 6189 9 observed observe VBN cord-006870-f5w6fw6q 6189 10 well well RB cord-006870-f5w6fw6q 6189 11 . . . cord-006870-f5w6fw6q 6190 1 Parenchymal parenchymal JJ cord-006870-f5w6fw6q 6190 2 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6190 3 was be VBD cord-006870-f5w6fw6q 6190 4 also also RB cord-006870-f5w6fw6q 6190 5 identified identify VBN cord-006870-f5w6fw6q 6190 6 and and CC cord-006870-f5w6fw6q 6190 7 confirmed confirm VBN cord-006870-f5w6fw6q 6190 8 for for IN cord-006870-f5w6fw6q 6190 9 removal removal NN cord-006870-f5w6fw6q 6190 10 using use VBG cord-006870-f5w6fw6q 6190 11 ultrasound ultrasound NN cord-006870-f5w6fw6q 6190 12 . . . cord-006870-f5w6fw6q 6191 1 In in IN cord-006870-f5w6fw6q 6191 2 severe severe JJ cord-006870-f5w6fw6q 6191 3 brain brain NN cord-006870-f5w6fw6q 6191 4 swelling swell VBG cord-006870-f5w6fw6q 6191 5 cases case NNS cord-006870-f5w6fw6q 6191 6 , , , cord-006870-f5w6fw6q 6191 7 arachnoid arachnoid JJ cord-006870-f5w6fw6q 6191 8 space space NN cord-006870-f5w6fw6q 6191 9 was be VBD cord-006870-f5w6fw6q 6191 10 seen see VBN cord-006870-f5w6fw6q 6191 11 increased increase VBN cord-006870-f5w6fw6q 6191 12 echogenicity echogenicity NN cord-006870-f5w6fw6q 6191 13 . . . cord-006870-f5w6fw6q 6192 1 Ultrasound ultrasound NN cord-006870-f5w6fw6q 6192 2 image image NN cord-006870-f5w6fw6q 6192 3 was be VBD cord-006870-f5w6fw6q 6192 4 compared compare VBN cord-006870-f5w6fw6q 6192 5 to to IN cord-006870-f5w6fw6q 6192 6 postoperative postoperative JJ cord-006870-f5w6fw6q 6192 7 CT CT NNP cord-006870-f5w6fw6q 6192 8 scan scan NN cord-006870-f5w6fw6q 6192 9 . . . cord-006870-f5w6fw6q 6193 1 Intra intra JJ cord-006870-f5w6fw6q 6193 2 - - JJ cord-006870-f5w6fw6q 6193 3 operative operative JJ cord-006870-f5w6fw6q 6193 4 ultrasound ultrasound NN cord-006870-f5w6fw6q 6193 5 is be VBZ cord-006870-f5w6fw6q 6193 6 effective effective JJ cord-006870-f5w6fw6q 6193 7 in in IN cord-006870-f5w6fw6q 6193 8 real real JJ cord-006870-f5w6fw6q 6193 9 time time NN cord-006870-f5w6fw6q 6193 10 inspection inspection NN cord-006870-f5w6fw6q 6193 11 of of IN cord-006870-f5w6fw6q 6193 12 brain brain NN cord-006870-f5w6fw6q 6193 13 during during IN cord-006870-f5w6fw6q 6193 14 surgery surgery NN cord-006870-f5w6fw6q 6193 15 and and CC cord-006870-f5w6fw6q 6193 16 may may MD cord-006870-f5w6fw6q 6193 17 helpful helpful JJ cord-006870-f5w6fw6q 6193 18 detect detect VB cord-006870-f5w6fw6q 6193 19 opposite opposite JJ cord-006870-f5w6fw6q 6193 20 or or CC cord-006870-f5w6fw6q 6193 21 parenchymal parenchymal JJ cord-006870-f5w6fw6q 6193 22 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6193 23 before before IN cord-006870-f5w6fw6q 6193 24 closure closure NN cord-006870-f5w6fw6q 6193 25 and and CC cord-006870-f5w6fw6q 6193 26 leaving leave VBG cord-006870-f5w6fw6q 6193 27 operation operation NN cord-006870-f5w6fw6q 6193 28 room room NN cord-006870-f5w6fw6q 6193 29 . . . cord-006870-f5w6fw6q 6194 1 To to TO cord-006870-f5w6fw6q 6194 2 describe describe VB cord-006870-f5w6fw6q 6194 3 a a DT cord-006870-f5w6fw6q 6194 4 rare rare JJ cord-006870-f5w6fw6q 6194 5 case case NN cord-006870-f5w6fw6q 6194 6 of of IN cord-006870-f5w6fw6q 6194 7 a a DT cord-006870-f5w6fw6q 6194 8 varicella varicella NN cord-006870-f5w6fw6q 6194 9 zoster zoster NN cord-006870-f5w6fw6q 6194 10 virus virus NN cord-006870-f5w6fw6q 6194 11 ( ( -LRB- cord-006870-f5w6fw6q 6194 12 VZV VZV NNP cord-006870-f5w6fw6q 6194 13 ) ) -RRB- cord-006870-f5w6fw6q 6194 14 meningitis meningitis NN cord-006870-f5w6fw6q 6194 15 with with IN cord-006870-f5w6fw6q 6194 16 progressive progressive JJ cord-006870-f5w6fw6q 6194 17 multiple multiple JJ cord-006870-f5w6fw6q 6194 18 cranial cranial JJ cord-006870-f5w6fw6q 6194 19 nerve nerve NN cord-006870-f5w6fw6q 6194 20 deficits deficit NNS cord-006870-f5w6fw6q 6194 21 in in IN cord-006870-f5w6fw6q 6194 22 the the DT cord-006870-f5w6fw6q 6194 23 absence absence NN cord-006870-f5w6fw6q 6194 24 of of IN cord-006870-f5w6fw6q 6194 25 cutaneous cutaneous JJ cord-006870-f5w6fw6q 6194 26 zoster zoster NN cord-006870-f5w6fw6q 6194 27 rash rash NN cord-006870-f5w6fw6q 6194 28 . . . cord-006870-f5w6fw6q 6195 1 A a DT cord-006870-f5w6fw6q 6195 2 young young JJ cord-006870-f5w6fw6q 6195 3 woman woman NN cord-006870-f5w6fw6q 6195 4 with with IN cord-006870-f5w6fw6q 6195 5 idiopathic idiopathic JJ cord-006870-f5w6fw6q 6195 6 thrombocytopenic thrombocytopenic JJ cord-006870-f5w6fw6q 6195 7 pupura pupura NN cord-006870-f5w6fw6q 6195 8 on on IN cord-006870-f5w6fw6q 6195 9 steroids steroid NNS cord-006870-f5w6fw6q 6195 10 presents present VBZ cord-006870-f5w6fw6q 6195 11 with with IN cord-006870-f5w6fw6q 6195 12 horizontal horizontal JJ cord-006870-f5w6fw6q 6195 13 diplopia diplopia NN cord-006870-f5w6fw6q 6195 14 in in IN cord-006870-f5w6fw6q 6195 15 the the DT cord-006870-f5w6fw6q 6195 16 setting setting NN cord-006870-f5w6fw6q 6195 17 of of IN cord-006870-f5w6fw6q 6195 18 seven seven CD cord-006870-f5w6fw6q 6195 19 days day NNS cord-006870-f5w6fw6q 6195 20 of of IN cord-006870-f5w6fw6q 6195 21 intractable intractable JJ cord-006870-f5w6fw6q 6195 22 headache headache NN cord-006870-f5w6fw6q 6195 23 . . . cord-006870-f5w6fw6q 6196 1 She -PRON- PRP cord-006870-f5w6fw6q 6196 2 had have VBD cord-006870-f5w6fw6q 6196 3 no no DT cord-006870-f5w6fw6q 6196 4 meningeal meningeal JJ cord-006870-f5w6fw6q 6196 5 signs sign NNS cord-006870-f5w6fw6q 6196 6 , , , cord-006870-f5w6fw6q 6196 7 fever fever NN cord-006870-f5w6fw6q 6196 8 , , , cord-006870-f5w6fw6q 6196 9 leukocytosis leukocytosis NN cord-006870-f5w6fw6q 6196 10 or or CC cord-006870-f5w6fw6q 6196 11 cutaneous cutaneous JJ cord-006870-f5w6fw6q 6196 12 rash rash NN cord-006870-f5w6fw6q 6196 13 . . . cord-006870-f5w6fw6q 6197 1 Within within IN cord-006870-f5w6fw6q 6197 2 three three CD cord-006870-f5w6fw6q 6197 3 days day NNS cord-006870-f5w6fw6q 6197 4 into into IN cord-006870-f5w6fw6q 6197 5 hospitalization hospitalization NN cord-006870-f5w6fw6q 6197 6 , , , cord-006870-f5w6fw6q 6197 7 she -PRON- PRP cord-006870-f5w6fw6q 6197 8 developed develop VBD cord-006870-f5w6fw6q 6197 9 bilateral bilateral JJ cord-006870-f5w6fw6q 6197 10 CN CN NNP cord-006870-f5w6fw6q 6197 11 VI VI NNP cord-006870-f5w6fw6q 6197 12 , , , cord-006870-f5w6fw6q 6197 13 CN CN NNP cord-006870-f5w6fw6q 6197 14 III III NNP cord-006870-f5w6fw6q 6197 15 , , , cord-006870-f5w6fw6q 6197 16 right right JJ cord-006870-f5w6fw6q 6197 17 CN cn NN cord-006870-f5w6fw6q 6197 18 V v NN cord-006870-f5w6fw6q 6197 19 and and CC cord-006870-f5w6fw6q 6197 20 right right JJ cord-006870-f5w6fw6q 6197 21 CN CN NNP cord-006870-f5w6fw6q 6197 22 VII VII NNP cord-006870-f5w6fw6q 6197 23 palsies palsy NNS cord-006870-f5w6fw6q 6197 24 in in IN cord-006870-f5w6fw6q 6197 25 a a DT cord-006870-f5w6fw6q 6197 26 progressive progressive JJ cord-006870-f5w6fw6q 6197 27 fashion fashion NN cord-006870-f5w6fw6q 6197 28 . . . cord-006870-f5w6fw6q 6198 1 CSF CSF NNP cord-006870-f5w6fw6q 6198 2 analysis analysis NN cord-006870-f5w6fw6q 6198 3 revealed reveal VBD cord-006870-f5w6fw6q 6198 4 cell cell NN cord-006870-f5w6fw6q 6198 5 count count NN cord-006870-f5w6fw6q 6198 6 of of IN cord-006870-f5w6fw6q 6198 7 1,146 1,146 CD cord-006870-f5w6fw6q 6198 8 / / SYM cord-006870-f5w6fw6q 6198 9 mm3 mm3 NNS cord-006870-f5w6fw6q 6198 10 , , , cord-006870-f5w6fw6q 6198 11 a a DT cord-006870-f5w6fw6q 6198 12 protein protein NN cord-006870-f5w6fw6q 6198 13 of of IN cord-006870-f5w6fw6q 6198 14 202 202 CD cord-006870-f5w6fw6q 6198 15 mg mg NNP cord-006870-f5w6fw6q 6198 16 / / SYM cord-006870-f5w6fw6q 6198 17 dL dl NN cord-006870-f5w6fw6q 6198 18 and and CC cord-006870-f5w6fw6q 6198 19 glucose glucose NN cord-006870-f5w6fw6q 6198 20 8 8 CD cord-006870-f5w6fw6q 6198 21 mg mg NNP cord-006870-f5w6fw6q 6198 22 / / SYM cord-006870-f5w6fw6q 6198 23 dL. dL. NNS cord-006870-f5w6fw6q 6198 24 Cytology Cytology NNP cord-006870-f5w6fw6q 6198 25 , , , cord-006870-f5w6fw6q 6198 26 tuberculosis tuberculosis NN cord-006870-f5w6fw6q 6198 27 , , , cord-006870-f5w6fw6q 6198 28 bacterial bacterial JJ cord-006870-f5w6fw6q 6198 29 and and CC cord-006870-f5w6fw6q 6198 30 fungal fungal JJ cord-006870-f5w6fw6q 6198 31 cultures culture NNS cord-006870-f5w6fw6q 6198 32 , , , cord-006870-f5w6fw6q 6198 33 ACE ACE NNP cord-006870-f5w6fw6q 6198 34 and and CC cord-006870-f5w6fw6q 6198 35 HIV HIV NNP cord-006870-f5w6fw6q 6198 36 testing testing NN cord-006870-f5w6fw6q 6198 37 were be VBD cord-006870-f5w6fw6q 6198 38 negative negative JJ cord-006870-f5w6fw6q 6198 39 . . . cord-006870-f5w6fw6q 6199 1 VZV VZV NNP cord-006870-f5w6fw6q 6199 2 - - HYPH cord-006870-f5w6fw6q 6199 3 DNA DNA NNP cord-006870-f5w6fw6q 6199 4 was be VBD cord-006870-f5w6fw6q 6199 5 detected detect VBN cord-006870-f5w6fw6q 6199 6 in in IN cord-006870-f5w6fw6q 6199 7 CSF CSF NNP cord-006870-f5w6fw6q 6199 8 in in IN cord-006870-f5w6fw6q 6199 9 high high JJ cord-006870-f5w6fw6q 6199 10 titers titer NNS cord-006870-f5w6fw6q 6199 11 VZV VZV NNP cord-006870-f5w6fw6q 6199 12 Quant Quant NNP cord-006870-f5w6fw6q 6199 13 : : : cord-006870-f5w6fw6q 6200 1 3.9million 3.9million NNP cord-006870-f5w6fw6q 6200 2 . . . cord-006870-f5w6fw6q 6201 1 Contrasted contrast VBN cord-006870-f5w6fw6q 6201 2 brain brain NN cord-006870-f5w6fw6q 6201 3 MRI MRI NNP cord-006870-f5w6fw6q 6201 4 revealed reveal VBD cord-006870-f5w6fw6q 6201 5 mild mild JJ cord-006870-f5w6fw6q 6201 6 diffuse diffuse JJ cord-006870-f5w6fw6q 6201 7 leptomeningeal leptomeningeal NN cord-006870-f5w6fw6q 6201 8 enhancement enhancement NN cord-006870-f5w6fw6q 6201 9 in in IN cord-006870-f5w6fw6q 6201 10 the the DT cord-006870-f5w6fw6q 6201 11 basilar basilar JJ cord-006870-f5w6fw6q 6201 12 region region NN cord-006870-f5w6fw6q 6201 13 . . . cord-006870-f5w6fw6q 6202 1 She -PRON- PRP cord-006870-f5w6fw6q 6202 2 recovered recover VBD cord-006870-f5w6fw6q 6202 3 almost almost RB cord-006870-f5w6fw6q 6202 4 all all DT cord-006870-f5w6fw6q 6202 5 cranial cranial JJ cord-006870-f5w6fw6q 6202 6 nerve nerve NN cord-006870-f5w6fw6q 6202 7 function function NN cord-006870-f5w6fw6q 6202 8 within within IN cord-006870-f5w6fw6q 6202 9 10 10 CD cord-006870-f5w6fw6q 6202 10 days day NNS cord-006870-f5w6fw6q 6202 11 of of IN cord-006870-f5w6fw6q 6202 12 treatment treatment NN cord-006870-f5w6fw6q 6202 13 with with IN cord-006870-f5w6fw6q 6202 14 acyclovir acyclovir NNP cord-006870-f5w6fw6q 6202 15 and and CC cord-006870-f5w6fw6q 6202 16 high high JJ cord-006870-f5w6fw6q 6202 17 dose dose NN cord-006870-f5w6fw6q 6202 18 steroids steroid NNS cord-006870-f5w6fw6q 6202 19 . . . cord-006870-f5w6fw6q 6203 1 A a DT cord-006870-f5w6fw6q 6203 2 diagnosis diagnosis NN cord-006870-f5w6fw6q 6203 3 of of IN cord-006870-f5w6fw6q 6203 4 polyneuritis polyneuritis NN cord-006870-f5w6fw6q 6203 5 cranialis cranialis NNP cord-006870-f5w6fw6q 6203 6 with with IN cord-006870-f5w6fw6q 6203 7 zoster zoster NNP cord-006870-f5w6fw6q 6203 8 sine sine NNP cord-006870-f5w6fw6q 6203 9 herpete herpete NNP cord-006870-f5w6fw6q 6203 10 ( ( -LRB- cord-006870-f5w6fw6q 6203 11 ZSH ZSH NNP cord-006870-f5w6fw6q 6203 12 ) ) -RRB- cord-006870-f5w6fw6q 6203 13 was be VBD cord-006870-f5w6fw6q 6203 14 made make VBN cord-006870-f5w6fw6q 6203 15 given give VBN cord-006870-f5w6fw6q 6203 16 PCR PCR NNP cord-006870-f5w6fw6q 6203 17 positive positive JJ cord-006870-f5w6fw6q 6203 18 VZV VZV NNP cord-006870-f5w6fw6q 6203 19 - - HYPH cord-006870-f5w6fw6q 6203 20 DNA DNA NNP cord-006870-f5w6fw6q 6203 21 in in IN cord-006870-f5w6fw6q 6203 22 CSF CSF NNP cord-006870-f5w6fw6q 6203 23 . . . cord-006870-f5w6fw6q 6204 1 VZV VZV NNP cord-006870-f5w6fw6q 6204 2 reactivation reactivation NN cord-006870-f5w6fw6q 6204 3 with with IN cord-006870-f5w6fw6q 6204 4 a a DT cord-006870-f5w6fw6q 6204 5 wide wide JJ cord-006870-f5w6fw6q 6204 6 array array NN cord-006870-f5w6fw6q 6204 7 of of IN cord-006870-f5w6fw6q 6204 8 neurological neurological JJ cord-006870-f5w6fw6q 6204 9 deficits deficit NNS cord-006870-f5w6fw6q 6204 10 can can MD cord-006870-f5w6fw6q 6204 11 present present VB cord-006870-f5w6fw6q 6204 12 without without IN cord-006870-f5w6fw6q 6204 13 rash rash JJ cord-006870-f5w6fw6q 6204 14 making make VBG cord-006870-f5w6fw6q 6204 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 6204 16 challenging challenging JJ cord-006870-f5w6fw6q 6204 17 . . . cord-006870-f5w6fw6q 6205 1 ZSH zsh NN cord-006870-f5w6fw6q 6205 2 should should MD cord-006870-f5w6fw6q 6205 3 be be VB cord-006870-f5w6fw6q 6205 4 in in IN cord-006870-f5w6fw6q 6205 5 the the DT cord-006870-f5w6fw6q 6205 6 differential differential NN cord-006870-f5w6fw6q 6205 7 for for IN cord-006870-f5w6fw6q 6205 8 acute acute JJ cord-006870-f5w6fw6q 6205 9 cranial cranial JJ cord-006870-f5w6fw6q 6205 10 nerve nerve NN cord-006870-f5w6fw6q 6205 11 deficits deficit NNS cord-006870-f5w6fw6q 6205 12 as as IN cord-006870-f5w6fw6q 6205 13 prompt prompt JJ cord-006870-f5w6fw6q 6205 14 treatment treatment NN cord-006870-f5w6fw6q 6205 15 with with IN cord-006870-f5w6fw6q 6205 16 acyclovir acyclovir NNP cord-006870-f5w6fw6q 6205 17 can can MD cord-006870-f5w6fw6q 6205 18 lead lead VB cord-006870-f5w6fw6q 6205 19 to to IN cord-006870-f5w6fw6q 6205 20 rapid rapid JJ cord-006870-f5w6fw6q 6205 21 recovery recovery NN cord-006870-f5w6fw6q 6205 22 . . . cord-006870-f5w6fw6q 6206 1 Stress stress NN cord-006870-f5w6fw6q 6206 2 - - HYPH cord-006870-f5w6fw6q 6206 3 induced induce VBN cord-006870-f5w6fw6q 6206 4 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 6206 5 or or CC cord-006870-f5w6fw6q 6206 6 neurogenic neurogenic JJ cord-006870-f5w6fw6q 6206 7 stunned stunned JJ cord-006870-f5w6fw6q 6206 8 myocardium myocardium NN cord-006870-f5w6fw6q 6206 9 is be VBZ cord-006870-f5w6fw6q 6206 10 a a DT cord-006870-f5w6fw6q 6206 11 well well RB cord-006870-f5w6fw6q 6206 12 - - HYPH cord-006870-f5w6fw6q 6206 13 documented document VBN cord-006870-f5w6fw6q 6206 14 cardiac cardiac JJ cord-006870-f5w6fw6q 6206 15 complication complication NN cord-006870-f5w6fw6q 6206 16 following follow VBG cord-006870-f5w6fw6q 6206 17 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 6206 18 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6206 19 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6206 20 ( ( -LRB- cord-006870-f5w6fw6q 6206 21 SAH SAH NNP cord-006870-f5w6fw6q 6206 22 ) ) -RRB- cord-006870-f5w6fw6q 6206 23 . . . cord-006870-f5w6fw6q 6207 1 Onset onset NN cord-006870-f5w6fw6q 6207 2 is be VBZ cord-006870-f5w6fw6q 6207 3 usually usually RB cord-006870-f5w6fw6q 6207 4 immediate immediate JJ cord-006870-f5w6fw6q 6207 5 , , , cord-006870-f5w6fw6q 6207 6 within within IN cord-006870-f5w6fw6q 6207 7 hours hour NNS cord-006870-f5w6fw6q 6207 8 after after IN cord-006870-f5w6fw6q 6207 9 aneurysm aneurysm NN cord-006870-f5w6fw6q 6207 10 rupture rupture NN cord-006870-f5w6fw6q 6207 11 , , , cord-006870-f5w6fw6q 6207 12 and and CC cord-006870-f5w6fw6q 6207 13 is be VBZ cord-006870-f5w6fw6q 6207 14 characterized characterize VBN cord-006870-f5w6fw6q 6207 15 by by IN cord-006870-f5w6fw6q 6207 16 left left JJ cord-006870-f5w6fw6q 6207 17 ventricular ventricular JJ cord-006870-f5w6fw6q 6207 18 dysfunction dysfunction NN cord-006870-f5w6fw6q 6207 19 with with IN cord-006870-f5w6fw6q 6207 20 pulmonary pulmonary JJ cord-006870-f5w6fw6q 6207 21 edema edema NN cord-006870-f5w6fw6q 6207 22 and and CC cord-006870-f5w6fw6q 6207 23 elevation elevation NN cord-006870-f5w6fw6q 6207 24 in in IN cord-006870-f5w6fw6q 6207 25 cardiac cardiac JJ cord-006870-f5w6fw6q 6207 26 biomarkers biomarker NNS cord-006870-f5w6fw6q 6207 27 . . . cord-006870-f5w6fw6q 6208 1 This this DT cord-006870-f5w6fw6q 6208 2 can can MD cord-006870-f5w6fw6q 6208 3 often often RB cord-006870-f5w6fw6q 6208 4 be be VB cord-006870-f5w6fw6q 6208 5 mistaken mistake VBN cord-006870-f5w6fw6q 6208 6 for for IN cord-006870-f5w6fw6q 6208 7 an an DT cord-006870-f5w6fw6q 6208 8 acute acute JJ cord-006870-f5w6fw6q 6208 9 myocardial myocardial JJ cord-006870-f5w6fw6q 6208 10 infarction infarction NN cord-006870-f5w6fw6q 6208 11 or or CC cord-006870-f5w6fw6q 6208 12 ischemia ischemia NN cord-006870-f5w6fw6q 6208 13 . . . cord-006870-f5w6fw6q 6209 1 The the DT cord-006870-f5w6fw6q 6209 2 pathogenesis pathogenesis NN cord-006870-f5w6fw6q 6209 3 appears appear VBZ cord-006870-f5w6fw6q 6209 4 to to TO cord-006870-f5w6fw6q 6209 5 be be VB cord-006870-f5w6fw6q 6209 6 the the DT cord-006870-f5w6fw6q 6209 7 result result NN cord-006870-f5w6fw6q 6209 8 of of IN cord-006870-f5w6fw6q 6209 9 elevated elevated JJ cord-006870-f5w6fw6q 6209 10 catecholamine catecholamine NN cord-006870-f5w6fw6q 6209 11 levels level NNS cord-006870-f5w6fw6q 6209 12 following follow VBG cord-006870-f5w6fw6q 6209 13 injury injury NN cord-006870-f5w6fw6q 6209 14 leading lead VBG cord-006870-f5w6fw6q 6209 15 to to IN cord-006870-f5w6fw6q 6209 16 myocardial myocardial JJ cord-006870-f5w6fw6q 6209 17 contraction contraction NN cord-006870-f5w6fw6q 6209 18 band band NN cord-006870-f5w6fw6q 6209 19 necrosis necrosis NN cord-006870-f5w6fw6q 6209 20 and and CC cord-006870-f5w6fw6q 6209 21 cardiac cardiac JJ cord-006870-f5w6fw6q 6209 22 dysfunction dysfunction NN cord-006870-f5w6fw6q 6209 23 . . . cord-006870-f5w6fw6q 6210 1 This this DT cord-006870-f5w6fw6q 6210 2 syndrome syndrome NN cord-006870-f5w6fw6q 6210 3 occurs occur VBZ cord-006870-f5w6fw6q 6210 4 more more RBR cord-006870-f5w6fw6q 6210 5 commonly commonly RB cord-006870-f5w6fw6q 6210 6 in in IN cord-006870-f5w6fw6q 6210 7 patients patient NNS cord-006870-f5w6fw6q 6210 8 with with IN cord-006870-f5w6fw6q 6210 9 severe severe JJ cord-006870-f5w6fw6q 6210 10 or or CC cord-006870-f5w6fw6q 6210 11 " " `` cord-006870-f5w6fw6q 6210 12 high high JJ cord-006870-f5w6fw6q 6210 13 - - HYPH cord-006870-f5w6fw6q 6210 14 grade grade NN cord-006870-f5w6fw6q 6210 15 " " `` cord-006870-f5w6fw6q 6210 16 SAH SAH NNP cord-006870-f5w6fw6q 6210 17 . . . cord-006870-f5w6fw6q 6211 1 We -PRON- PRP cord-006870-f5w6fw6q 6211 2 review review VBP cord-006870-f5w6fw6q 6211 3 a a DT cord-006870-f5w6fw6q 6211 4 case case NN cord-006870-f5w6fw6q 6211 5 of of IN cord-006870-f5w6fw6q 6211 6 delayed delayed JJ cord-006870-f5w6fw6q 6211 7 cardiac cardiac JJ cord-006870-f5w6fw6q 6211 8 dysfunction dysfunction NN cord-006870-f5w6fw6q 6211 9 coinciding coincide VBG cord-006870-f5w6fw6q 6211 10 with with IN cord-006870-f5w6fw6q 6211 11 the the DT cord-006870-f5w6fw6q 6211 12 onset onset NN cord-006870-f5w6fw6q 6211 13 of of IN cord-006870-f5w6fw6q 6211 14 vasospasm vasospasm NN cord-006870-f5w6fw6q 6211 15 . . . cord-006870-f5w6fw6q 6212 1 A a DT cord-006870-f5w6fw6q 6212 2 52-year 52-year JJ cord-006870-f5w6fw6q 6212 3 - - HYPH cord-006870-f5w6fw6q 6212 4 old old JJ cord-006870-f5w6fw6q 6212 5 female female NN cord-006870-f5w6fw6q 6212 6 presented present VBN cord-006870-f5w6fw6q 6212 7 with with IN cord-006870-f5w6fw6q 6212 8 a a DT cord-006870-f5w6fw6q 6212 9 H&H3 H&H3 NNP cord-006870-f5w6fw6q 6212 10 , , , cord-006870-f5w6fw6q 6212 11 mF4 mF4 NNP cord-006870-f5w6fw6q 6212 12 SAH SAH NNP cord-006870-f5w6fw6q 6212 13 . . . cord-006870-f5w6fw6q 6213 1 She -PRON- PRP cord-006870-f5w6fw6q 6213 2 appeared appear VBD cord-006870-f5w6fw6q 6213 3 to to TO cord-006870-f5w6fw6q 6213 4 have have VB cord-006870-f5w6fw6q 6213 5 lost lose VBN cord-006870-f5w6fw6q 6213 6 consciousness consciousness NN cord-006870-f5w6fw6q 6213 7 prior prior RB cord-006870-f5w6fw6q 6213 8 to to IN cord-006870-f5w6fw6q 6213 9 arrival arrival NN cord-006870-f5w6fw6q 6213 10 and and CC cord-006870-f5w6fw6q 6213 11 was be VBD cord-006870-f5w6fw6q 6213 12 reporting report VBG cord-006870-f5w6fw6q 6213 13 worst bad JJS cord-006870-f5w6fw6q 6213 14 headache headache NN cord-006870-f5w6fw6q 6213 15 of of IN cord-006870-f5w6fw6q 6213 16 life life NN cord-006870-f5w6fw6q 6213 17 . . . cord-006870-f5w6fw6q 6214 1 She -PRON- PRP cord-006870-f5w6fw6q 6214 2 had have VBD cord-006870-f5w6fw6q 6214 3 an an DT cord-006870-f5w6fw6q 6214 4 EVD EVD NNP cord-006870-f5w6fw6q 6214 5 placed place VBN cord-006870-f5w6fw6q 6214 6 upon upon IN cord-006870-f5w6fw6q 6214 7 arrival arrival NN cord-006870-f5w6fw6q 6214 8 with with IN cord-006870-f5w6fw6q 6214 9 opening open VBG cord-006870-f5w6fw6q 6214 10 pressure pressure NN cord-006870-f5w6fw6q 6214 11 at at IN cord-006870-f5w6fw6q 6214 12 27 27 CD cord-006870-f5w6fw6q 6214 13 . . . cord-006870-f5w6fw6q 6215 1 She -PRON- PRP cord-006870-f5w6fw6q 6215 2 underwent undergo VBD cord-006870-f5w6fw6q 6215 3 endovascular endovascular JJ cord-006870-f5w6fw6q 6215 4 coiling coiling NN cord-006870-f5w6fw6q 6215 5 of of IN cord-006870-f5w6fw6q 6215 6 a a DT cord-006870-f5w6fw6q 6215 7 ruptured ruptured JJ cord-006870-f5w6fw6q 6215 8 aneurysm aneurysm NN cord-006870-f5w6fw6q 6215 9 of of IN cord-006870-f5w6fw6q 6215 10 her -PRON- PRP$ cord-006870-f5w6fw6q 6215 11 anterior anterior JJ cord-006870-f5w6fw6q 6215 12 communicating communicate VBG cord-006870-f5w6fw6q 6215 13 artery artery NN cord-006870-f5w6fw6q 6215 14 aneurysm aneurysm NN cord-006870-f5w6fw6q 6215 15 . . . cord-006870-f5w6fw6q 6216 1 Initial initial JJ cord-006870-f5w6fw6q 6216 2 echocardiogram echocardiogram NN cord-006870-f5w6fw6q 6216 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6216 4 normal normal JJ cord-006870-f5w6fw6q 6216 5 wall wall NN cord-006870-f5w6fw6q 6216 6 motion motion NN cord-006870-f5w6fw6q 6216 7 with with IN cord-006870-f5w6fw6q 6216 8 EF EF NNP cord-006870-f5w6fw6q 6216 9 of of IN cord-006870-f5w6fw6q 6216 10 63 63 CD cord-006870-f5w6fw6q 6216 11 % % NN cord-006870-f5w6fw6q 6216 12 , , , cord-006870-f5w6fw6q 6216 13 and and CC cord-006870-f5w6fw6q 6217 1 minimal minimal JJ cord-006870-f5w6fw6q 6217 2 troponin troponin JJ cord-006870-f5w6fw6q 6217 3 I -PRON- PRP cord-006870-f5w6fw6q 6217 4 elevation elevation VBP cord-006870-f5w6fw6q 6217 5 at at IN cord-006870-f5w6fw6q 6217 6 0.04 0.04 CD cord-006870-f5w6fw6q 6217 7 ng ng NN cord-006870-f5w6fw6q 6217 8 / / SYM cord-006870-f5w6fw6q 6217 9 mL. ml. NN cord-006870-f5w6fw6q 6218 1 On on IN cord-006870-f5w6fw6q 6218 2 post post JJ cord-006870-f5w6fw6q 6218 3 - - JJ cord-006870-f5w6fw6q 6218 4 bleed bleed JJ cord-006870-f5w6fw6q 6218 5 day day NN cord-006870-f5w6fw6q 6218 6 10 10 CD cord-006870-f5w6fw6q 6218 7 the the DT cord-006870-f5w6fw6q 6218 8 patient patient NN cord-006870-f5w6fw6q 6218 9 became become VBD cord-006870-f5w6fw6q 6218 10 more more RBR cord-006870-f5w6fw6q 6218 11 somnolent somnolent JJ cord-006870-f5w6fw6q 6218 12 and and CC cord-006870-f5w6fw6q 6218 13 developed developed JJ cord-006870-f5w6fw6q 6218 14 chest chest NN cord-006870-f5w6fw6q 6218 15 pain pain NN cord-006870-f5w6fw6q 6218 16 with with IN cord-006870-f5w6fw6q 6218 17 an an DT cord-006870-f5w6fw6q 6218 18 ECG ECG NNP cord-006870-f5w6fw6q 6218 19 demonstrating demonstrate VBG cord-006870-f5w6fw6q 6218 20 ST ST NNP cord-006870-f5w6fw6q 6218 21 - - HYPH cord-006870-f5w6fw6q 6218 22 elevation elevation NN cord-006870-f5w6fw6q 6218 23 in in IN cord-006870-f5w6fw6q 6218 24 all all DT cord-006870-f5w6fw6q 6218 25 anterolateral anterolateral JJ cord-006870-f5w6fw6q 6218 26 leads lead NNS cord-006870-f5w6fw6q 6218 27 concerning concern VBG cord-006870-f5w6fw6q 6218 28 for for IN cord-006870-f5w6fw6q 6218 29 ACS ACS NNP cord-006870-f5w6fw6q 6218 30 . . . cord-006870-f5w6fw6q 6219 1 She -PRON- PRP cord-006870-f5w6fw6q 6219 2 was be VBD cord-006870-f5w6fw6q 6219 3 taken take VBN cord-006870-f5w6fw6q 6219 4 for for IN cord-006870-f5w6fw6q 6219 5 cardiac cardiac JJ cord-006870-f5w6fw6q 6219 6 catheterization catheterization NN cord-006870-f5w6fw6q 6219 7 where where WRB cord-006870-f5w6fw6q 6219 8 she -PRON- PRP cord-006870-f5w6fw6q 6219 9 had have VBD cord-006870-f5w6fw6q 6219 10 non non JJ cord-006870-f5w6fw6q 6219 11 - - JJ cord-006870-f5w6fw6q 6219 12 obstructive obstructive JJ cord-006870-f5w6fw6q 6219 13 vessels vessel NNS cord-006870-f5w6fw6q 6219 14 with with IN cord-006870-f5w6fw6q 6219 15 no no DT cord-006870-f5w6fw6q 6219 16 vasospasm vasospasm NN cord-006870-f5w6fw6q 6219 17 seen see VBN cord-006870-f5w6fw6q 6219 18 . . . cord-006870-f5w6fw6q 6220 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6220 2 EF ef NN cord-006870-f5w6fw6q 6220 3 was be VBD cord-006870-f5w6fw6q 6220 4 reported report VBN cord-006870-f5w6fw6q 6220 5 at at IN cord-006870-f5w6fw6q 6220 6 25 25 CD cord-006870-f5w6fw6q 6220 7 - - SYM cord-006870-f5w6fw6q 6220 8 35 35 CD cord-006870-f5w6fw6q 6220 9 % % NN cord-006870-f5w6fw6q 6220 10 with with IN cord-006870-f5w6fw6q 6220 11 apical apical JJ cord-006870-f5w6fw6q 6220 12 ballooning ballooning NN cord-006870-f5w6fw6q 6220 13 present present NN cord-006870-f5w6fw6q 6220 14 . . . cord-006870-f5w6fw6q 6221 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6221 2 repeat repeat NN cord-006870-f5w6fw6q 6221 3 echocardiogram echocardiogram NN cord-006870-f5w6fw6q 6221 4 also also RB cord-006870-f5w6fw6q 6221 5 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6221 6 a a DT cord-006870-f5w6fw6q 6221 7 new new JJ cord-006870-f5w6fw6q 6221 8 apical apical JJ cord-006870-f5w6fw6q 6221 9 akinesis akinesis NN cord-006870-f5w6fw6q 6221 10 with with IN cord-006870-f5w6fw6q 6221 11 EF EF NNP cord-006870-f5w6fw6q 6221 12 45 45 CD cord-006870-f5w6fw6q 6221 13 % % NN cord-006870-f5w6fw6q 6221 14 , , , cord-006870-f5w6fw6q 6221 15 and and CC cord-006870-f5w6fw6q 6221 16 troponin troponin NN cord-006870-f5w6fw6q 6221 17 peaked peak VBD cord-006870-f5w6fw6q 6221 18 to to IN cord-006870-f5w6fw6q 6221 19 16 16 CD cord-006870-f5w6fw6q 6221 20 ng ng NN cord-006870-f5w6fw6q 6221 21 / / SYM cord-006870-f5w6fw6q 6221 22 mL. mL. NNP cord-006870-f5w6fw6q 6221 23 Her -PRON- PRP$ cord-006870-f5w6fw6q 6221 24 TCDs tcd NNS cord-006870-f5w6fw6q 6221 25 at at IN cord-006870-f5w6fw6q 6221 26 the the DT cord-006870-f5w6fw6q 6221 27 time time NN cord-006870-f5w6fw6q 6221 28 were be VBD cord-006870-f5w6fw6q 6221 29 suggestive suggestive JJ cord-006870-f5w6fw6q 6221 30 of of IN cord-006870-f5w6fw6q 6221 31 vasospasm vasospasm NN cord-006870-f5w6fw6q 6221 32 with with IN cord-006870-f5w6fw6q 6221 33 bilateral bilateral JJ cord-006870-f5w6fw6q 6221 34 LR lr NN cord-006870-f5w6fw6q 6221 35 > > XX cord-006870-f5w6fw6q 6221 36 3 3 CD cord-006870-f5w6fw6q 6221 37 , , , cord-006870-f5w6fw6q 6221 38 but but CC cord-006870-f5w6fw6q 6221 39 no no DT cord-006870-f5w6fw6q 6221 40 focal focal JJ cord-006870-f5w6fw6q 6221 41 deficit deficit NN cord-006870-f5w6fw6q 6221 42 present present JJ cord-006870-f5w6fw6q 6221 43 . . . cord-006870-f5w6fw6q 6222 1 It -PRON- PRP cord-006870-f5w6fw6q 6222 2 appears appear VBZ cord-006870-f5w6fw6q 6222 3 that that IN cord-006870-f5w6fw6q 6222 4 regardless regardless RB cord-006870-f5w6fw6q 6222 5 of of IN cord-006870-f5w6fw6q 6222 6 timeline timeline NN cord-006870-f5w6fw6q 6222 7 , , , cord-006870-f5w6fw6q 6222 8 stress stress NN cord-006870-f5w6fw6q 6222 9 - - HYPH cord-006870-f5w6fw6q 6222 10 induced induce VBN cord-006870-f5w6fw6q 6222 11 cardiomyopathy cardiomyopathy NN cord-006870-f5w6fw6q 6222 12 or or CC cord-006870-f5w6fw6q 6222 13 neurogenic neurogenic JJ cord-006870-f5w6fw6q 6222 14 stunned stunned JJ cord-006870-f5w6fw6q 6222 15 myocardium myocardium NN cord-006870-f5w6fw6q 6222 16 occurs occur VBZ cord-006870-f5w6fw6q 6222 17 after after IN cord-006870-f5w6fw6q 6222 18 sympathetic sympathetic JJ cord-006870-f5w6fw6q 6222 19 or or CC cord-006870-f5w6fw6q 6222 20 catecholamine catecholamine NN cord-006870-f5w6fw6q 6222 21 surge surge NN cord-006870-f5w6fw6q 6222 22 and and CC cord-006870-f5w6fw6q 6222 23 may may MD cord-006870-f5w6fw6q 6222 24 occur occur VB cord-006870-f5w6fw6q 6222 25 after after IN cord-006870-f5w6fw6q 6222 26 the the DT cord-006870-f5w6fw6q 6222 27 onset onset NN cord-006870-f5w6fw6q 6222 28 of of IN cord-006870-f5w6fw6q 6222 29 vasospasm vasospasm NN cord-006870-f5w6fw6q 6222 30 in in IN cord-006870-f5w6fw6q 6222 31 patients patient NNS cord-006870-f5w6fw6q 6222 32 with with IN cord-006870-f5w6fw6q 6222 33 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 6222 34 SAH SAH NNP cord-006870-f5w6fw6q 6222 35 . . . cord-006870-f5w6fw6q 6223 1 The the DT cord-006870-f5w6fw6q 6223 2 rapid rapid JJ cord-006870-f5w6fw6q 6223 3 neurological neurological JJ cord-006870-f5w6fw6q 6223 4 assessment assessment NN cord-006870-f5w6fw6q 6223 5 of of IN cord-006870-f5w6fw6q 6223 6 critically critically RB cord-006870-f5w6fw6q 6223 7 ill ill JJ cord-006870-f5w6fw6q 6223 8 patients patient NNS cord-006870-f5w6fw6q 6223 9 with with IN cord-006870-f5w6fw6q 6223 10 neurologic neurologic JJ cord-006870-f5w6fw6q 6223 11 disease disease NN cord-006870-f5w6fw6q 6223 12 is be VBZ cord-006870-f5w6fw6q 6223 13 paramount paramount NN cord-006870-f5w6fw6q 6223 14 when when WRB cord-006870-f5w6fw6q 6223 15 determining determine VBG cord-006870-f5w6fw6q 6223 16 a a DT cord-006870-f5w6fw6q 6223 17 course course NN cord-006870-f5w6fw6q 6223 18 of of IN cord-006870-f5w6fw6q 6223 19 action action NN cord-006870-f5w6fw6q 6223 20 . . . cord-006870-f5w6fw6q 6224 1 Neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6224 2 blockade blockade NN cord-006870-f5w6fw6q 6224 3 is be VBZ cord-006870-f5w6fw6q 6224 4 often often RB cord-006870-f5w6fw6q 6224 5 used use VBN cord-006870-f5w6fw6q 6224 6 during during IN cord-006870-f5w6fw6q 6224 7 critical critical JJ cord-006870-f5w6fw6q 6224 8 care care NN cord-006870-f5w6fw6q 6224 9 transport transport NN cord-006870-f5w6fw6q 6224 10 and and CC cord-006870-f5w6fw6q 6224 11 in in IN cord-006870-f5w6fw6q 6224 12 the the DT cord-006870-f5w6fw6q 6224 13 emergency emergency NN cord-006870-f5w6fw6q 6224 14 department department NN cord-006870-f5w6fw6q 6224 15 . . . cord-006870-f5w6fw6q 6225 1 Unfortunately unfortunately RB cord-006870-f5w6fw6q 6225 2 , , , cord-006870-f5w6fw6q 6225 3 this this DT cord-006870-f5w6fw6q 6225 4 can can MD cord-006870-f5w6fw6q 6225 5 delay delay VB cord-006870-f5w6fw6q 6225 6 examination examination NN cord-006870-f5w6fw6q 6225 7 and and CC cord-006870-f5w6fw6q 6225 8 assessment assessment NN cord-006870-f5w6fw6q 6225 9 leading lead VBG cord-006870-f5w6fw6q 6225 10 to to IN cord-006870-f5w6fw6q 6225 11 unnecessary unnecessary JJ cord-006870-f5w6fw6q 6225 12 testing testing NN cord-006870-f5w6fw6q 6225 13 and and CC cord-006870-f5w6fw6q 6225 14 procedures procedure NNS cord-006870-f5w6fw6q 6225 15 . . . cord-006870-f5w6fw6q 6226 1 Historically historically RB cord-006870-f5w6fw6q 6226 2 , , , cord-006870-f5w6fw6q 6226 3 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6226 4 blockade blockade NN cord-006870-f5w6fw6q 6226 5 reversal reversal NN cord-006870-f5w6fw6q 6226 6 was be VBD cord-006870-f5w6fw6q 6226 7 accomplished accomplish VBN cord-006870-f5w6fw6q 6226 8 using use VBG cord-006870-f5w6fw6q 6226 9 a a DT cord-006870-f5w6fw6q 6226 10 combination combination NN cord-006870-f5w6fw6q 6226 11 of of IN cord-006870-f5w6fw6q 6226 12 neostigmine neostigmine NN cord-006870-f5w6fw6q 6226 13 and and CC cord-006870-f5w6fw6q 6226 14 glycopyrrolate glycopyrrolate NN cord-006870-f5w6fw6q 6226 15 . . . cord-006870-f5w6fw6q 6227 1 However however RB cord-006870-f5w6fw6q 6227 2 , , , cord-006870-f5w6fw6q 6227 3 this this DT cord-006870-f5w6fw6q 6227 4 can can MD cord-006870-f5w6fw6q 6227 5 lead lead VB cord-006870-f5w6fw6q 6227 6 to to IN cord-006870-f5w6fw6q 6227 7 incomplete incomplete JJ cord-006870-f5w6fw6q 6227 8 reversal reversal NN cord-006870-f5w6fw6q 6227 9 and and CC cord-006870-f5w6fw6q 6227 10 unwanted unwanted JJ cord-006870-f5w6fw6q 6227 11 side side NN cord-006870-f5w6fw6q 6227 12 effects effect NNS cord-006870-f5w6fw6q 6227 13 from from IN cord-006870-f5w6fw6q 6227 14 these these DT cord-006870-f5w6fw6q 6227 15 medications medication NNS cord-006870-f5w6fw6q 6227 16 . . . cord-006870-f5w6fw6q 6228 1 Sugammadex Sugammadex NNP cord-006870-f5w6fw6q 6228 2 is be VBZ cord-006870-f5w6fw6q 6228 3 a a DT cord-006870-f5w6fw6q 6228 4 cyclodextran cyclodextran JJ cord-006870-f5w6fw6q 6228 5 injectable injectable JJ cord-006870-f5w6fw6q 6228 6 compound compound NN cord-006870-f5w6fw6q 6228 7 that that WDT cord-006870-f5w6fw6q 6228 8 has have VBZ cord-006870-f5w6fw6q 6228 9 been be VBN cord-006870-f5w6fw6q 6228 10 FDA FDA NNP cord-006870-f5w6fw6q 6228 11 approved approve VBN cord-006870-f5w6fw6q 6228 12 in in IN cord-006870-f5w6fw6q 6228 13 the the DT cord-006870-f5w6fw6q 6228 14 United United NNP cord-006870-f5w6fw6q 6228 15 States States NNP cord-006870-f5w6fw6q 6228 16 since since IN cord-006870-f5w6fw6q 6228 17 2015 2015 CD cord-006870-f5w6fw6q 6228 18 for for IN cord-006870-f5w6fw6q 6228 19 rapid rapid JJ cord-006870-f5w6fw6q 6228 20 reversal reversal NN cord-006870-f5w6fw6q 6228 21 of of IN cord-006870-f5w6fw6q 6228 22 rocuronium rocuronium NN cord-006870-f5w6fw6q 6228 23 induced induce VBN cord-006870-f5w6fw6q 6228 24 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6228 25 blockade blockade NN cord-006870-f5w6fw6q 6228 26 . . . cord-006870-f5w6fw6q 6229 1 Sugammadex sugammadex JJ cord-006870-f5w6fw6q 6229 2 works work VBZ cord-006870-f5w6fw6q 6229 3 by by IN cord-006870-f5w6fw6q 6229 4 forming form VBG cord-006870-f5w6fw6q 6229 5 a a DT cord-006870-f5w6fw6q 6229 6 complex complex NN cord-006870-f5w6fw6q 6229 7 with with IN cord-006870-f5w6fw6q 6229 8 rocuronium rocuronium NN cord-006870-f5w6fw6q 6229 9 and and CC cord-006870-f5w6fw6q 6229 10 rendering render VBG cord-006870-f5w6fw6q 6229 11 it -PRON- PRP cord-006870-f5w6fw6q 6229 12 unable unable JJ cord-006870-f5w6fw6q 6229 13 to to TO cord-006870-f5w6fw6q 6229 14 bind bind VB cord-006870-f5w6fw6q 6229 15 to to IN cord-006870-f5w6fw6q 6229 16 nicotinic nicotinic JJ cord-006870-f5w6fw6q 6229 17 cholinergic cholinergic JJ cord-006870-f5w6fw6q 6229 18 receptors receptor NNS cord-006870-f5w6fw6q 6229 19 at at IN cord-006870-f5w6fw6q 6229 20 the the DT cord-006870-f5w6fw6q 6229 21 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6229 22 junction junction NN cord-006870-f5w6fw6q 6229 23 . . . cord-006870-f5w6fw6q 6230 1 Sugammadex Sugammadex NNP cord-006870-f5w6fw6q 6230 2 can can MD cord-006870-f5w6fw6q 6230 3 reverse reverse VB cord-006870-f5w6fw6q 6230 4 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6230 5 blockade blockade NN cord-006870-f5w6fw6q 6230 6 without without IN cord-006870-f5w6fw6q 6230 7 the the DT cord-006870-f5w6fw6q 6230 8 unwanted unwanted JJ cord-006870-f5w6fw6q 6230 9 side side NN cord-006870-f5w6fw6q 6230 10 effects effect NNS cord-006870-f5w6fw6q 6230 11 of of IN cord-006870-f5w6fw6q 6230 12 cholinesterase cholinesterase NN cord-006870-f5w6fw6q 6230 13 inhibitors inhibitor NNS cord-006870-f5w6fw6q 6230 14 . . . cord-006870-f5w6fw6q 6231 1 This this DT cord-006870-f5w6fw6q 6231 2 is be VBZ cord-006870-f5w6fw6q 6231 3 a a DT cord-006870-f5w6fw6q 6231 4 case case NN cord-006870-f5w6fw6q 6231 5 report report NN cord-006870-f5w6fw6q 6231 6 of of IN cord-006870-f5w6fw6q 6231 7 the the DT cord-006870-f5w6fw6q 6231 8 successful successful JJ cord-006870-f5w6fw6q 6231 9 use use NN cord-006870-f5w6fw6q 6231 10 of of IN cord-006870-f5w6fw6q 6231 11 sugammadex sugammadex NN cord-006870-f5w6fw6q 6231 12 to to TO cord-006870-f5w6fw6q 6231 13 reverse reverse VB cord-006870-f5w6fw6q 6231 14 the the DT cord-006870-f5w6fw6q 6231 15 effects effect NNS cord-006870-f5w6fw6q 6231 16 of of IN cord-006870-f5w6fw6q 6231 17 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6231 18 blockade blockade NN cord-006870-f5w6fw6q 6231 19 in in IN cord-006870-f5w6fw6q 6231 20 an an DT cord-006870-f5w6fw6q 6231 21 intracerebral intracerebral JJ cord-006870-f5w6fw6q 6231 22 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6231 23 patient patient JJ cord-006870-f5w6fw6q 6231 24 . . . cord-006870-f5w6fw6q 6232 1 A a DT cord-006870-f5w6fw6q 6232 2 77 77 CD cord-006870-f5w6fw6q 6232 3 year year NN cord-006870-f5w6fw6q 6232 4 old old JJ cord-006870-f5w6fw6q 6232 5 male male NN cord-006870-f5w6fw6q 6232 6 with with IN cord-006870-f5w6fw6q 6232 7 a a DT cord-006870-f5w6fw6q 6232 8 history history NN cord-006870-f5w6fw6q 6232 9 of of IN cord-006870-f5w6fw6q 6232 10 atrial atrial JJ cord-006870-f5w6fw6q 6232 11 fibrillation fibrillation NN cord-006870-f5w6fw6q 6232 12 and and CC cord-006870-f5w6fw6q 6232 13 a a DT cord-006870-f5w6fw6q 6232 14 supratherapeutic supratherapeutic JJ cord-006870-f5w6fw6q 6232 15 INR INR NNP cord-006870-f5w6fw6q 6232 16 presented present VBD cord-006870-f5w6fw6q 6232 17 via via IN cord-006870-f5w6fw6q 6232 18 aeromedical aeromedical JJ cord-006870-f5w6fw6q 6232 19 ambulance ambulance NN cord-006870-f5w6fw6q 6232 20 with with IN cord-006870-f5w6fw6q 6232 21 a a DT cord-006870-f5w6fw6q 6232 22 63 63 CD cord-006870-f5w6fw6q 6232 23 mL ml NN cord-006870-f5w6fw6q 6232 24 left leave VBN cord-006870-f5w6fw6q 6232 25 frontal frontal JJ cord-006870-f5w6fw6q 6232 26 intracerebral intracerebral NNP cord-006870-f5w6fw6q 6232 27 hermorrhage hermorrhage NNP cord-006870-f5w6fw6q 6232 28 causing cause VBG cord-006870-f5w6fw6q 6232 29 a a DT cord-006870-f5w6fw6q 6232 30 10 10 CD cord-006870-f5w6fw6q 6232 31 mm mm NNP cord-006870-f5w6fw6q 6232 32 midline midline NN cord-006870-f5w6fw6q 6232 33 shift shift NN cord-006870-f5w6fw6q 6232 34 . . . cord-006870-f5w6fw6q 6233 1 He -PRON- PRP cord-006870-f5w6fw6q 6233 2 received receive VBD cord-006870-f5w6fw6q 6233 3 a a DT cord-006870-f5w6fw6q 6233 4 100 100 CD cord-006870-f5w6fw6q 6233 5 mg mg NNP cord-006870-f5w6fw6q 6233 6 bolus bolus NN cord-006870-f5w6fw6q 6233 7 of of IN cord-006870-f5w6fw6q 6233 8 rocuronium rocuronium NN cord-006870-f5w6fw6q 6233 9 prior prior RB cord-006870-f5w6fw6q 6233 10 to to IN cord-006870-f5w6fw6q 6233 11 arrival arrival NN cord-006870-f5w6fw6q 6233 12 and and CC cord-006870-f5w6fw6q 6233 13 had have VBD cord-006870-f5w6fw6q 6233 14 a a DT cord-006870-f5w6fw6q 6233 15 GCS GCS NNP cord-006870-f5w6fw6q 6233 16 of of IN cord-006870-f5w6fw6q 6233 17 3 3 CD cord-006870-f5w6fw6q 6233 18 upon upon IN cord-006870-f5w6fw6q 6233 19 presenting present VBG cord-006870-f5w6fw6q 6233 20 to to IN cord-006870-f5w6fw6q 6233 21 the the DT cord-006870-f5w6fw6q 6233 22 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 6233 23 ICU ICU NNP cord-006870-f5w6fw6q 6233 24 . . . cord-006870-f5w6fw6q 6234 1 A a DT cord-006870-f5w6fw6q 6234 2 train train NN cord-006870-f5w6fw6q 6234 3 - - HYPH cord-006870-f5w6fw6q 6234 4 of of IN cord-006870-f5w6fw6q 6234 5 - - HYPH cord-006870-f5w6fw6q 6234 6 four four CD cord-006870-f5w6fw6q 6234 7 revealed reveal VBD cord-006870-f5w6fw6q 6234 8 0/4 0/4 CD cord-006870-f5w6fw6q 6234 9 twitches twitch NNS cord-006870-f5w6fw6q 6234 10 . . . cord-006870-f5w6fw6q 6235 1 He -PRON- PRP cord-006870-f5w6fw6q 6235 2 was be VBD cord-006870-f5w6fw6q 6235 3 given give VBN cord-006870-f5w6fw6q 6235 4 4 4 CD cord-006870-f5w6fw6q 6235 5 mg mg NNP cord-006870-f5w6fw6q 6235 6 / / SYM cord-006870-f5w6fw6q 6235 7 kg kg NNP cord-006870-f5w6fw6q 6235 8 of of IN cord-006870-f5w6fw6q 6235 9 sugammadex sugammadex NN cord-006870-f5w6fw6q 6235 10 with with IN cord-006870-f5w6fw6q 6235 11 a a DT cord-006870-f5w6fw6q 6235 12 return return NN cord-006870-f5w6fw6q 6235 13 of of IN cord-006870-f5w6fw6q 6235 14 4/4 4/4 CD cord-006870-f5w6fw6q 6235 15 twitches twitch NNS cord-006870-f5w6fw6q 6235 16 within within IN cord-006870-f5w6fw6q 6235 17 30 30 CD cord-006870-f5w6fw6q 6235 18 seconds second NNS cord-006870-f5w6fw6q 6235 19 . . . cord-006870-f5w6fw6q 6236 1 A a DT cord-006870-f5w6fw6q 6236 2 more more RBR cord-006870-f5w6fw6q 6236 3 accurate accurate JJ cord-006870-f5w6fw6q 6236 4 neurological neurological JJ cord-006870-f5w6fw6q 6236 5 examination examination NN cord-006870-f5w6fw6q 6236 6 was be VBD cord-006870-f5w6fw6q 6236 7 then then RB cord-006870-f5w6fw6q 6236 8 obtained obtain VBN cord-006870-f5w6fw6q 6236 9 demonstrating demonstrate VBG cord-006870-f5w6fw6q 6236 10 that that IN cord-006870-f5w6fw6q 6236 11 his -PRON- PRP$ cord-006870-f5w6fw6q 6236 12 brainstem brainstem NN cord-006870-f5w6fw6q 6236 13 reflexes reflex NNS cord-006870-f5w6fw6q 6236 14 were be VBD cord-006870-f5w6fw6q 6236 15 intact intact JJ cord-006870-f5w6fw6q 6236 16 , , , cord-006870-f5w6fw6q 6236 17 he -PRON- PRP cord-006870-f5w6fw6q 6236 18 could could MD cord-006870-f5w6fw6q 6236 19 open open VB cord-006870-f5w6fw6q 6236 20 his -PRON- PRP$ cord-006870-f5w6fw6q 6236 21 eyes eye NNS cord-006870-f5w6fw6q 6236 22 spontaneously spontaneously RB cord-006870-f5w6fw6q 6236 23 and and CC cord-006870-f5w6fw6q 6236 24 reacted react VBD cord-006870-f5w6fw6q 6236 25 purposefully purposefully RB cord-006870-f5w6fw6q 6236 26 to to IN cord-006870-f5w6fw6q 6236 27 painful painful JJ cord-006870-f5w6fw6q 6236 28 stimulation stimulation NN cord-006870-f5w6fw6q 6236 29 . . . cord-006870-f5w6fw6q 6237 1 This this DT cord-006870-f5w6fw6q 6237 2 allowed allow VBD cord-006870-f5w6fw6q 6237 3 a a DT cord-006870-f5w6fw6q 6237 4 non non JJ cord-006870-f5w6fw6q 6237 5 - - JJ cord-006870-f5w6fw6q 6237 6 operative operative JJ cord-006870-f5w6fw6q 6237 7 course course NN cord-006870-f5w6fw6q 6237 8 to to TO cord-006870-f5w6fw6q 6237 9 be be VB cord-006870-f5w6fw6q 6237 10 taken take VBN cord-006870-f5w6fw6q 6237 11 . . . cord-006870-f5w6fw6q 6238 1 Sugammadex Sugammadex NNP cord-006870-f5w6fw6q 6238 2 can can MD cord-006870-f5w6fw6q 6238 3 reliably reliably RB cord-006870-f5w6fw6q 6238 4 and and CC cord-006870-f5w6fw6q 6238 5 quickly quickly RB cord-006870-f5w6fw6q 6238 6 reverse reverse VB cord-006870-f5w6fw6q 6238 7 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6238 8 blockade blockade NN cord-006870-f5w6fw6q 6238 9 allowing allow VBG cord-006870-f5w6fw6q 6238 10 for for IN cord-006870-f5w6fw6q 6238 11 the the DT cord-006870-f5w6fw6q 6238 12 immediate immediate JJ cord-006870-f5w6fw6q 6238 13 assessment assessment NN cord-006870-f5w6fw6q 6238 14 of of IN cord-006870-f5w6fw6q 6238 15 the the DT cord-006870-f5w6fw6q 6238 16 neurocritical neurocritical NNP cord-006870-f5w6fw6q 6238 17 care care NN cord-006870-f5w6fw6q 6238 18 patient patient NN cord-006870-f5w6fw6q 6238 19 . . . cord-006870-f5w6fw6q 6239 1 It -PRON- PRP cord-006870-f5w6fw6q 6239 2 is be VBZ cord-006870-f5w6fw6q 6239 3 a a DT cord-006870-f5w6fw6q 6239 4 useful useful JJ cord-006870-f5w6fw6q 6239 5 tool tool NN cord-006870-f5w6fw6q 6239 6 with with IN cord-006870-f5w6fw6q 6239 7 minimal minimal JJ cord-006870-f5w6fw6q 6239 8 side side NN cord-006870-f5w6fw6q 6239 9 effects effect NNS cord-006870-f5w6fw6q 6239 10 . . . cord-006870-f5w6fw6q 6240 1 Piperacillin Piperacillin NNP cord-006870-f5w6fw6q 6240 2 - - HYPH cord-006870-f5w6fw6q 6240 3 tazobactam tazobactam NNP cord-006870-f5w6fw6q 6240 4 is be VBZ cord-006870-f5w6fw6q 6240 5 commonly commonly RB cord-006870-f5w6fw6q 6240 6 deployed deploy VBN cord-006870-f5w6fw6q 6240 7 as as IN cord-006870-f5w6fw6q 6240 8 empiric empiric JJ cord-006870-f5w6fw6q 6240 9 antibiotic antibiotic JJ cord-006870-f5w6fw6q 6240 10 therapy therapy NN cord-006870-f5w6fw6q 6240 11 . . . cord-006870-f5w6fw6q 6241 1 Piperacillin Piperacillin NNP cord-006870-f5w6fw6q 6241 2 - - HYPH cord-006870-f5w6fw6q 6241 3 induced induce VBN cord-006870-f5w6fw6q 6241 4 hematologic hematologic JJ cord-006870-f5w6fw6q 6241 5 laboratory laboratory NN cord-006870-f5w6fw6q 6241 6 test test NN cord-006870-f5w6fw6q 6241 7 abnormalities abnormality NNS cord-006870-f5w6fw6q 6241 8 were be VBD cord-006870-f5w6fw6q 6241 9 rare rare JJ cord-006870-f5w6fw6q 6241 10 in in IN cord-006870-f5w6fw6q 6241 11 pre pre JJ cord-006870-f5w6fw6q 6241 12 - - JJ cord-006870-f5w6fw6q 6241 13 marketing marketing JJ cord-006870-f5w6fw6q 6241 14 studies study NNS cord-006870-f5w6fw6q 6241 15 , , , cord-006870-f5w6fw6q 6241 16 and and CC cord-006870-f5w6fw6q 6241 17 whether whether IN cord-006870-f5w6fw6q 6241 18 these these DT cord-006870-f5w6fw6q 6241 19 alterations alteration NNS cord-006870-f5w6fw6q 6241 20 are be VBP cord-006870-f5w6fw6q 6241 21 of of IN cord-006870-f5w6fw6q 6241 22 clinical clinical JJ cord-006870-f5w6fw6q 6241 23 significance significance NN cord-006870-f5w6fw6q 6241 24 has have VBZ cord-006870-f5w6fw6q 6241 25 been be VBN cord-006870-f5w6fw6q 6241 26 studied study VBN cord-006870-f5w6fw6q 6241 27 little little JJ cord-006870-f5w6fw6q 6241 28 . . . cord-006870-f5w6fw6q 6242 1 Aberrations aberration NNS cord-006870-f5w6fw6q 6242 2 in in IN cord-006870-f5w6fw6q 6242 3 platelet platelet NN cord-006870-f5w6fw6q 6242 4 function function NN cord-006870-f5w6fw6q 6242 5 have have VBP cord-006870-f5w6fw6q 6242 6 not not RB cord-006870-f5w6fw6q 6242 7 been be VBN cord-006870-f5w6fw6q 6242 8 implicated implicate VBN cord-006870-f5w6fw6q 6242 9 . . . cord-006870-f5w6fw6q 6243 1 In in IN cord-006870-f5w6fw6q 6243 2 the the DT cord-006870-f5w6fw6q 6243 3 present present JJ cord-006870-f5w6fw6q 6243 4 case case NN cord-006870-f5w6fw6q 6243 5 , , , cord-006870-f5w6fw6q 6243 6 we -PRON- PRP cord-006870-f5w6fw6q 6243 7 discuss discuss VBP cord-006870-f5w6fw6q 6243 8 a a DT cord-006870-f5w6fw6q 6243 9 patient patient NN cord-006870-f5w6fw6q 6243 10 presenting present VBG cord-006870-f5w6fw6q 6243 11 with with IN cord-006870-f5w6fw6q 6243 12 hypertensive hypertensive JJ cord-006870-f5w6fw6q 6243 13 intracerebral intracerebral JJ cord-006870-f5w6fw6q 6243 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6243 15 ( ( -LRB- cord-006870-f5w6fw6q 6243 16 ICH ICH NNP cord-006870-f5w6fw6q 6243 17 ) ) -RRB- cord-006870-f5w6fw6q 6243 18 who who WP cord-006870-f5w6fw6q 6243 19 sustained sustain VBD cord-006870-f5w6fw6q 6243 20 two two CD cord-006870-f5w6fw6q 6243 21 additional additional JJ cord-006870-f5w6fw6q 6243 22 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 6243 23 in in IN cord-006870-f5w6fw6q 6243 24 distinct distinct JJ cord-006870-f5w6fw6q 6243 25 locations location NNS cord-006870-f5w6fw6q 6243 26 after after IN cord-006870-f5w6fw6q 6243 27 routine routine JJ cord-006870-f5w6fw6q 6243 28 removal removal NN cord-006870-f5w6fw6q 6243 29 of of IN cord-006870-f5w6fw6q 6243 30 intracranial intracranial JJ cord-006870-f5w6fw6q 6243 31 monitors monitor NNS cord-006870-f5w6fw6q 6243 32 and and CC cord-006870-f5w6fw6q 6243 33 an an DT cord-006870-f5w6fw6q 6243 34 external external JJ cord-006870-f5w6fw6q 6243 35 ventricular ventricular JJ cord-006870-f5w6fw6q 6243 36 drain drain NN cord-006870-f5w6fw6q 6243 37 ( ( -LRB- cord-006870-f5w6fw6q 6243 38 EVD EVD NNP cord-006870-f5w6fw6q 6243 39 ) ) -RRB- cord-006870-f5w6fw6q 6243 40 . . . cord-006870-f5w6fw6q 6244 1 These these DT cord-006870-f5w6fw6q 6244 2 significant significant JJ cord-006870-f5w6fw6q 6244 3 bleeding bleed VBG cord-006870-f5w6fw6q 6244 4 events event NNS cord-006870-f5w6fw6q 6244 5 occurred occur VBD cord-006870-f5w6fw6q 6244 6 exclusively exclusively RB cord-006870-f5w6fw6q 6244 7 during during IN cord-006870-f5w6fw6q 6244 8 piperacillin piperacillin NNP cord-006870-f5w6fw6q 6244 9 - - HYPH cord-006870-f5w6fw6q 6244 10 tazobactam tazobactam NNS cord-006870-f5w6fw6q 6244 11 therapy therapy NN cord-006870-f5w6fw6q 6244 12 and and CC cord-006870-f5w6fw6q 6244 13 were be VBD cord-006870-f5w6fw6q 6244 14 correlated correlate VBN cord-006870-f5w6fw6q 6244 15 with with IN cord-006870-f5w6fw6q 6244 16 new new JJ cord-006870-f5w6fw6q 6244 17 abnormalities abnormality NNS cord-006870-f5w6fw6q 6244 18 in in IN cord-006870-f5w6fw6q 6244 19 the the DT cord-006870-f5w6fw6q 6244 20 patient patient NN cord-006870-f5w6fw6q 6244 21 's 's POS cord-006870-f5w6fw6q 6244 22 platelet platelet NN cord-006870-f5w6fw6q 6244 23 function function NN cord-006870-f5w6fw6q 6244 24 assay assay NN cord-006870-f5w6fw6q 6244 25 ( ( -LRB- cord-006870-f5w6fw6q 6244 26 PFA PFA NNP cord-006870-f5w6fw6q 6244 27 ) ) -RRB- cord-006870-f5w6fw6q 6244 28 results result NNS cord-006870-f5w6fw6q 6244 29 . . . cord-006870-f5w6fw6q 6245 1 A a DT cord-006870-f5w6fw6q 6245 2 55-year 55-year JJ cord-006870-f5w6fw6q 6245 3 old old JJ cord-006870-f5w6fw6q 6245 4 Vietnamese vietnamese JJ cord-006870-f5w6fw6q 6245 5 male male NN cord-006870-f5w6fw6q 6245 6 with with IN cord-006870-f5w6fw6q 6245 7 hypertension hypertension NN cord-006870-f5w6fw6q 6245 8 presented present VBN cord-006870-f5w6fw6q 6245 9 for for IN cord-006870-f5w6fw6q 6245 10 treatment treatment NN cord-006870-f5w6fw6q 6245 11 of of IN cord-006870-f5w6fw6q 6245 12 a a DT cord-006870-f5w6fw6q 6245 13 left left JJ cord-006870-f5w6fw6q 6245 14 basal basal NN cord-006870-f5w6fw6q 6245 15 ganglia ganglion NNS cord-006870-f5w6fw6q 6245 16 ICH ICH NNP cord-006870-f5w6fw6q 6245 17 . . . cord-006870-f5w6fw6q 6246 1 Epinephrine epinephrine NN cord-006870-f5w6fw6q 6246 2 / / SYM cord-006870-f5w6fw6q 6246 3 collagen collagen NN cord-006870-f5w6fw6q 6246 4 and and CC cord-006870-f5w6fw6q 6246 5 adenosine adenosine NN cord-006870-f5w6fw6q 6246 6 diphosphate diphosphate NN cord-006870-f5w6fw6q 6246 7 / / SYM cord-006870-f5w6fw6q 6246 8 collagen collagen NN cord-006870-f5w6fw6q 6246 9 PFAs pfa NNS cord-006870-f5w6fw6q 6246 10 at at IN cord-006870-f5w6fw6q 6246 11 the the DT cord-006870-f5w6fw6q 6246 12 time time NN cord-006870-f5w6fw6q 6246 13 of of IN cord-006870-f5w6fw6q 6246 14 EVD EVD NNP cord-006870-f5w6fw6q 6246 15 and and CC cord-006870-f5w6fw6q 6246 16 quad quad JJ cord-006870-f5w6fw6q 6246 17 - - HYPH cord-006870-f5w6fw6q 6246 18 lumen lumen NN cord-006870-f5w6fw6q 6246 19 bolt bolt NN cord-006870-f5w6fw6q 6246 20 placement placement NN cord-006870-f5w6fw6q 6246 21 were be VBD cord-006870-f5w6fw6q 6246 22 normal normal JJ cord-006870-f5w6fw6q 6246 23 , , , cord-006870-f5w6fw6q 6246 24 and and CC cord-006870-f5w6fw6q 6246 25 imaging imaging NN cord-006870-f5w6fw6q 6246 26 showed show VBD cord-006870-f5w6fw6q 6246 27 no no DT cord-006870-f5w6fw6q 6246 28 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6246 29 after after IN cord-006870-f5w6fw6q 6246 30 placement placement NN cord-006870-f5w6fw6q 6246 31 . . . cord-006870-f5w6fw6q 6247 1 Hospital hospital NN cord-006870-f5w6fw6q 6247 2 course course NN cord-006870-f5w6fw6q 6247 3 was be VBD cord-006870-f5w6fw6q 6247 4 complicated complicate VBN cord-006870-f5w6fw6q 6247 5 by by IN cord-006870-f5w6fw6q 6247 6 aspiration aspiration NN cord-006870-f5w6fw6q 6247 7 pneumonia pneumonia NN cord-006870-f5w6fw6q 6247 8 requiring require VBG cord-006870-f5w6fw6q 6247 9 empiric empiric JJ cord-006870-f5w6fw6q 6247 10 piperacillin piperacillin NNP cord-006870-f5w6fw6q 6247 11 - - HYPH cord-006870-f5w6fw6q 6247 12 tazobactam tazobactam NNP cord-006870-f5w6fw6q 6247 13 administration administration NN cord-006870-f5w6fw6q 6247 14 . . . cord-006870-f5w6fw6q 6248 1 After after IN cord-006870-f5w6fw6q 6248 2 removal removal NN cord-006870-f5w6fw6q 6248 3 of of IN cord-006870-f5w6fw6q 6248 4 the the DT cord-006870-f5w6fw6q 6248 5 quad quad JJ cord-006870-f5w6fw6q 6248 6 - - HYPH cord-006870-f5w6fw6q 6248 7 lumen lumen NN cord-006870-f5w6fw6q 6248 8 bolt bolt NN cord-006870-f5w6fw6q 6248 9 and and CC cord-006870-f5w6fw6q 6248 10 EVD EVD NNP cord-006870-f5w6fw6q 6248 11 on on IN cord-006870-f5w6fw6q 6248 12 separate separate JJ cord-006870-f5w6fw6q 6248 13 days day NNS cord-006870-f5w6fw6q 6248 14 , , , cord-006870-f5w6fw6q 6248 15 both both DT cord-006870-f5w6fw6q 6248 16 follow follow NN cord-006870-f5w6fw6q 6248 17 - - HYPH cord-006870-f5w6fw6q 6248 18 up up RP cord-006870-f5w6fw6q 6248 19 CT CT NNP cord-006870-f5w6fw6q 6248 20 scans scan NNS cord-006870-f5w6fw6q 6248 21 showed show VBD cord-006870-f5w6fw6q 6248 22 new new JJ cord-006870-f5w6fw6q 6248 23 hematomas hematoma NNS cord-006870-f5w6fw6q 6248 24 in in IN cord-006870-f5w6fw6q 6248 25 the the DT cord-006870-f5w6fw6q 6248 26 devices device NNS cord-006870-f5w6fw6q 6248 27 ' ' POS cord-006870-f5w6fw6q 6248 28 tracts tract NNS cord-006870-f5w6fw6q 6248 29 , , , cord-006870-f5w6fw6q 6248 30 with with IN cord-006870-f5w6fw6q 6248 31 significant significant JJ cord-006870-f5w6fw6q 6248 32 intraventricular intraventricular JJ cord-006870-f5w6fw6q 6248 33 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6248 34 . . . cord-006870-f5w6fw6q 6249 1 Repeat repeat NN cord-006870-f5w6fw6q 6249 2 PFAs pfa NNS cord-006870-f5w6fw6q 6249 3 were be VBD cord-006870-f5w6fw6q 6249 4 abnormally abnormally RB cord-006870-f5w6fw6q 6249 5 prolonged prolong VBN cord-006870-f5w6fw6q 6249 6 , , , cord-006870-f5w6fw6q 6249 7 representing represent VBG cord-006870-f5w6fw6q 6249 8 a a DT cord-006870-f5w6fw6q 6249 9 distinct distinct JJ cord-006870-f5w6fw6q 6249 10 change change NN cord-006870-f5w6fw6q 6249 11 from from IN cord-006870-f5w6fw6q 6249 12 baseline baseline NN cord-006870-f5w6fw6q 6249 13 . . . cord-006870-f5w6fw6q 6250 1 A a DT cord-006870-f5w6fw6q 6250 2 trend trend NN cord-006870-f5w6fw6q 6250 3 toward toward IN cord-006870-f5w6fw6q 6250 4 normalization normalization NN cord-006870-f5w6fw6q 6250 5 of of IN cord-006870-f5w6fw6q 6250 6 PFAs pfa NNS cord-006870-f5w6fw6q 6250 7 was be VBD cord-006870-f5w6fw6q 6250 8 observed observe VBN cord-006870-f5w6fw6q 6250 9 after after IN cord-006870-f5w6fw6q 6250 10 discontinuation discontinuation NN cord-006870-f5w6fw6q 6250 11 of of IN cord-006870-f5w6fw6q 6250 12 piperacillin piperacillin NNP cord-006870-f5w6fw6q 6250 13 - - HYPH cord-006870-f5w6fw6q 6250 14 tazobactam tazobactam NNS cord-006870-f5w6fw6q 6250 15 with with IN cord-006870-f5w6fw6q 6250 16 progression progression NN cord-006870-f5w6fw6q 6250 17 toward toward IN cord-006870-f5w6fw6q 6250 18 baseline baseline NN cord-006870-f5w6fw6q 6250 19 thereafter thereafter RB cord-006870-f5w6fw6q 6250 20 . . . cord-006870-f5w6fw6q 6251 1 The the DT cord-006870-f5w6fw6q 6251 2 present present JJ cord-006870-f5w6fw6q 6251 3 case case NN cord-006870-f5w6fw6q 6251 4 is be VBZ cord-006870-f5w6fw6q 6251 5 unique unique JJ cord-006870-f5w6fw6q 6251 6 in in IN cord-006870-f5w6fw6q 6251 7 that that IN cord-006870-f5w6fw6q 6251 8 the the DT cord-006870-f5w6fw6q 6251 9 significant significant JJ cord-006870-f5w6fw6q 6251 10 bleeding bleeding NN cord-006870-f5w6fw6q 6251 11 that that WDT cord-006870-f5w6fw6q 6251 12 occurred occur VBD cord-006870-f5w6fw6q 6251 13 was be VBD cord-006870-f5w6fw6q 6251 14 attributable attributable JJ cord-006870-f5w6fw6q 6251 15 to to IN cord-006870-f5w6fw6q 6251 16 objectively objectively RB cord-006870-f5w6fw6q 6251 17 confirmed confirm VBN cord-006870-f5w6fw6q 6251 18 platelet platelet NN cord-006870-f5w6fw6q 6251 19 dysfunction dysfunction NN cord-006870-f5w6fw6q 6251 20 rather rather RB cord-006870-f5w6fw6q 6251 21 than than IN cord-006870-f5w6fw6q 6251 22 thrombocytopenia thrombocytopenia NN cord-006870-f5w6fw6q 6251 23 . . . cord-006870-f5w6fw6q 6252 1 Other other JJ cord-006870-f5w6fw6q 6252 2 possible possible JJ cord-006870-f5w6fw6q 6252 3 innate innate JJ cord-006870-f5w6fw6q 6252 4 causes cause NNS cord-006870-f5w6fw6q 6252 5 of of IN cord-006870-f5w6fw6q 6252 6 bleeding bleed VBG cord-006870-f5w6fw6q 6252 7 were be VBD cord-006870-f5w6fw6q 6252 8 less less RBR cord-006870-f5w6fw6q 6252 9 likely likely JJ cord-006870-f5w6fw6q 6252 10 as as IN cord-006870-f5w6fw6q 6252 11 the the DT cord-006870-f5w6fw6q 6252 12 patient patient NN cord-006870-f5w6fw6q 6252 13 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6252 14 normal normal JJ cord-006870-f5w6fw6q 6252 15 platelet platelet NN cord-006870-f5w6fw6q 6252 16 count count NN cord-006870-f5w6fw6q 6252 17 , , , cord-006870-f5w6fw6q 6252 18 von von NNP cord-006870-f5w6fw6q 6252 19 Willebrand Willebrand NNP cord-006870-f5w6fw6q 6252 20 multimers multimer NNS cord-006870-f5w6fw6q 6252 21 , , , cord-006870-f5w6fw6q 6252 22 platelet platelet NN cord-006870-f5w6fw6q 6252 23 morphology morphology NN cord-006870-f5w6fw6q 6252 24 , , , cord-006870-f5w6fw6q 6252 25 and and CC cord-006870-f5w6fw6q 6252 26 clotting clotting NN cord-006870-f5w6fw6q 6252 27 factors factor NNS cord-006870-f5w6fw6q 6252 28 . . . cord-006870-f5w6fw6q 6253 1 This this DT cord-006870-f5w6fw6q 6253 2 is be VBZ cord-006870-f5w6fw6q 6253 3 the the DT cord-006870-f5w6fw6q 6253 4 first first JJ cord-006870-f5w6fw6q 6253 5 reported report VBN cord-006870-f5w6fw6q 6253 6 case case NN cord-006870-f5w6fw6q 6253 7 of of IN cord-006870-f5w6fw6q 6253 8 intracranial intracranial JJ cord-006870-f5w6fw6q 6253 9 ( ( -LRB- cord-006870-f5w6fw6q 6253 10 periprocedural periprocedural JJ cord-006870-f5w6fw6q 6253 11 ) ) -RRB- cord-006870-f5w6fw6q 6253 12 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6253 13 potentially potentially RB cord-006870-f5w6fw6q 6253 14 related relate VBN cord-006870-f5w6fw6q 6253 15 to to IN cord-006870-f5w6fw6q 6253 16 piperacillin piperacillin NN cord-006870-f5w6fw6q 6253 17 - - HYPH cord-006870-f5w6fw6q 6253 18 tazobactam tazobactam NNS cord-006870-f5w6fw6q 6253 19 ; ; : cord-006870-f5w6fw6q 6253 20 further further JJ cord-006870-f5w6fw6q 6253 21 research research NN cord-006870-f5w6fw6q 6253 22 into into IN cord-006870-f5w6fw6q 6253 23 this this DT cord-006870-f5w6fw6q 6253 24 drug drug NN cord-006870-f5w6fw6q 6253 25 's 's POS cord-006870-f5w6fw6q 6253 26 impact impact NN cord-006870-f5w6fw6q 6253 27 upon upon IN cord-006870-f5w6fw6q 6253 28 qualitative qualitative JJ cord-006870-f5w6fw6q 6253 29 platelet platelet NN cord-006870-f5w6fw6q 6253 30 function function NN cord-006870-f5w6fw6q 6253 31 is be VBZ cord-006870-f5w6fw6q 6253 32 needed need VBN cord-006870-f5w6fw6q 6253 33 . . . cord-006870-f5w6fw6q 6254 1 The the DT cord-006870-f5w6fw6q 6254 2 life life NN cord-006870-f5w6fw6q 6254 3 - - HYPH cord-006870-f5w6fw6q 6254 4 saving save VBG cord-006870-f5w6fw6q 6254 5 potential potential NN cord-006870-f5w6fw6q 6254 6 of of IN cord-006870-f5w6fw6q 6254 7 extracorporeal extracorporeal JJ cord-006870-f5w6fw6q 6254 8 membrane membrane NN cord-006870-f5w6fw6q 6254 9 oxygenation oxygenation NN cord-006870-f5w6fw6q 6254 10 ( ( -LRB- cord-006870-f5w6fw6q 6254 11 ECMO ECMO NNP cord-006870-f5w6fw6q 6254 12 ) ) -RRB- cord-006870-f5w6fw6q 6254 13 has have VBZ cord-006870-f5w6fw6q 6254 14 been be VBN cord-006870-f5w6fw6q 6254 15 well well RB cord-006870-f5w6fw6q 6254 16 recognized recognize VBN cord-006870-f5w6fw6q 6254 17 since since IN cord-006870-f5w6fw6q 6254 18 the the DT cord-006870-f5w6fw6q 6254 19 1960s 1960 NNS cord-006870-f5w6fw6q 6254 20 . . . cord-006870-f5w6fw6q 6255 1 Modern modern JJ cord-006870-f5w6fw6q 6255 2 advancements advancement NNS cord-006870-f5w6fw6q 6255 3 of of IN cord-006870-f5w6fw6q 6255 4 research research NN cord-006870-f5w6fw6q 6255 5 and and CC cord-006870-f5w6fw6q 6255 6 technology technology NN cord-006870-f5w6fw6q 6255 7 have have VBP cord-006870-f5w6fw6q 6255 8 allowed allow VBN cord-006870-f5w6fw6q 6255 9 ECMO ECMO NNP cord-006870-f5w6fw6q 6255 10 to to TO cord-006870-f5w6fw6q 6255 11 be be VB cord-006870-f5w6fw6q 6255 12 accepted accept VBN cord-006870-f5w6fw6q 6255 13 as as IN cord-006870-f5w6fw6q 6255 14 a a DT cord-006870-f5w6fw6q 6255 15 dependable dependable JJ cord-006870-f5w6fw6q 6255 16 intervention intervention NN cord-006870-f5w6fw6q 6255 17 for for IN cord-006870-f5w6fw6q 6255 18 patients patient NNS cord-006870-f5w6fw6q 6255 19 with with IN cord-006870-f5w6fw6q 6255 20 severe severe JJ cord-006870-f5w6fw6q 6255 21 pulmonary pulmonary JJ cord-006870-f5w6fw6q 6255 22 or or CC cord-006870-f5w6fw6q 6255 23 cardiac cardiac JJ cord-006870-f5w6fw6q 6255 24 failure failure NN cord-006870-f5w6fw6q 6255 25 . . . cord-006870-f5w6fw6q 6256 1 However however RB cord-006870-f5w6fw6q 6256 2 , , , cord-006870-f5w6fw6q 6256 3 with with IN cord-006870-f5w6fw6q 6256 4 increased increase VBN cord-006870-f5w6fw6q 6256 5 use use NN cord-006870-f5w6fw6q 6256 6 , , , cord-006870-f5w6fw6q 6256 7 associated associated JJ cord-006870-f5w6fw6q 6256 8 complications complication NNS cord-006870-f5w6fw6q 6256 9 that that WDT cord-006870-f5w6fw6q 6256 10 detract detract VBP cord-006870-f5w6fw6q 6256 11 from from IN cord-006870-f5w6fw6q 6256 12 the the DT cord-006870-f5w6fw6q 6256 13 benefit benefit NN cord-006870-f5w6fw6q 6256 14 of of IN cord-006870-f5w6fw6q 6256 15 ECMO ECMO NNP cord-006870-f5w6fw6q 6256 16 are be VBP cord-006870-f5w6fw6q 6256 17 surfacing surface VBG cord-006870-f5w6fw6q 6256 18 as as RB cord-006870-f5w6fw6q 6256 19 well well RB cord-006870-f5w6fw6q 6256 20 . . . cord-006870-f5w6fw6q 6257 1 This this DT cord-006870-f5w6fw6q 6257 2 case case NN cord-006870-f5w6fw6q 6257 3 report report NN cord-006870-f5w6fw6q 6257 4 describes describe VBZ cord-006870-f5w6fw6q 6257 5 a a DT cord-006870-f5w6fw6q 6257 6 case case NN cord-006870-f5w6fw6q 6257 7 of of IN cord-006870-f5w6fw6q 6257 8 diffuse diffuse JJ cord-006870-f5w6fw6q 6257 9 intracerebral intracerebral JJ cord-006870-f5w6fw6q 6257 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6257 11 ( ( -LRB- cord-006870-f5w6fw6q 6257 12 ICH ICH NNP cord-006870-f5w6fw6q 6257 13 ) ) -RRB- cord-006870-f5w6fw6q 6257 14 after after IN cord-006870-f5w6fw6q 6257 15 prolonged prolong VBN cord-006870-f5w6fw6q 6257 16 ECMO ecmo NN cord-006870-f5w6fw6q 6257 17 resulting result VBG cord-006870-f5w6fw6q 6257 18 in in IN cord-006870-f5w6fw6q 6257 19 cerebral cerebral JJ cord-006870-f5w6fw6q 6257 20 edema edema NN cord-006870-f5w6fw6q 6257 21 , , , cord-006870-f5w6fw6q 6257 22 mass mass JJ cord-006870-f5w6fw6q 6257 23 effect effect NN cord-006870-f5w6fw6q 6257 24 , , , cord-006870-f5w6fw6q 6257 25 and and CC cord-006870-f5w6fw6q 6257 26 eventual eventual JJ cord-006870-f5w6fw6q 6257 27 brain brain NN cord-006870-f5w6fw6q 6257 28 herniation herniation NN cord-006870-f5w6fw6q 6257 29 . . . cord-006870-f5w6fw6q 6258 1 The the DT cord-006870-f5w6fw6q 6258 2 patient patient NN cord-006870-f5w6fw6q 6258 3 is be VBZ cord-006870-f5w6fw6q 6258 4 a a DT cord-006870-f5w6fw6q 6258 5 previously previously RB cord-006870-f5w6fw6q 6258 6 healthy healthy JJ cord-006870-f5w6fw6q 6258 7 19 19 CD cord-006870-f5w6fw6q 6258 8 year year NN cord-006870-f5w6fw6q 6258 9 old old JJ cord-006870-f5w6fw6q 6258 10 female female NN cord-006870-f5w6fw6q 6258 11 who who WP cord-006870-f5w6fw6q 6258 12 presented present VBD cord-006870-f5w6fw6q 6258 13 with with IN cord-006870-f5w6fw6q 6258 14 fever fever NN cord-006870-f5w6fw6q 6258 15 , , , cord-006870-f5w6fw6q 6258 16 chills chill NNS cord-006870-f5w6fw6q 6258 17 , , , cord-006870-f5w6fw6q 6258 18 and and CC cord-006870-f5w6fw6q 6258 19 myalgia myalgia NN cord-006870-f5w6fw6q 6258 20 . . . cord-006870-f5w6fw6q 6259 1 When when WRB cord-006870-f5w6fw6q 6259 2 evaluated evaluate VBN cord-006870-f5w6fw6q 6259 3 at at IN cord-006870-f5w6fw6q 6259 4 urgent urgent JJ cord-006870-f5w6fw6q 6259 5 care care NN cord-006870-f5w6fw6q 6259 6 , , , cord-006870-f5w6fw6q 6259 7 she -PRON- PRP cord-006870-f5w6fw6q 6259 8 was be VBD cord-006870-f5w6fw6q 6259 9 noted note VBN cord-006870-f5w6fw6q 6259 10 to to TO cord-006870-f5w6fw6q 6259 11 be be VB cord-006870-f5w6fw6q 6259 12 hypoxic hypoxic JJ cord-006870-f5w6fw6q 6259 13 and and CC cord-006870-f5w6fw6q 6259 14 was be VBD cord-006870-f5w6fw6q 6259 15 sent send VBN cord-006870-f5w6fw6q 6259 16 to to IN cord-006870-f5w6fw6q 6259 17 an an DT cord-006870-f5w6fw6q 6259 18 outside outside JJ cord-006870-f5w6fw6q 6259 19 hospital hospital NN cord-006870-f5w6fw6q 6259 20 where where WRB cord-006870-f5w6fw6q 6259 21 her -PRON- PRP$ cord-006870-f5w6fw6q 6259 22 Monospot Monospot NNP cord-006870-f5w6fw6q 6259 23 test test NN cord-006870-f5w6fw6q 6259 24 was be VBD cord-006870-f5w6fw6q 6259 25 positive positive JJ cord-006870-f5w6fw6q 6259 26 . . . cord-006870-f5w6fw6q 6260 1 Upon upon IN cord-006870-f5w6fw6q 6260 2 arrival arrival NN cord-006870-f5w6fw6q 6260 3 , , , cord-006870-f5w6fw6q 6260 4 the the DT cord-006870-f5w6fw6q 6260 5 patient patient NN cord-006870-f5w6fw6q 6260 6 was be VBD cord-006870-f5w6fw6q 6260 7 placed place VBN cord-006870-f5w6fw6q 6260 8 on on IN cord-006870-f5w6fw6q 6260 9 venovenous venovenous JJ cord-006870-f5w6fw6q 6260 10 ECMO ECMO NNP cord-006870-f5w6fw6q 6260 11 ( ( -LRB- cord-006870-f5w6fw6q 6260 12 VV VV NNP cord-006870-f5w6fw6q 6260 13 - - HYPH cord-006870-f5w6fw6q 6260 14 ECMO ECMO NNP cord-006870-f5w6fw6q 6260 15 ) ) -RRB- cord-006870-f5w6fw6q 6260 16 due due JJ cord-006870-f5w6fw6q 6260 17 to to IN cord-006870-f5w6fw6q 6260 18 severe severe JJ cord-006870-f5w6fw6q 6260 19 hypoxia hypoxia NN cord-006870-f5w6fw6q 6260 20 . . . cord-006870-f5w6fw6q 6261 1 She -PRON- PRP cord-006870-f5w6fw6q 6261 2 was be VBD cord-006870-f5w6fw6q 6261 3 also also RB cord-006870-f5w6fw6q 6261 4 in in IN cord-006870-f5w6fw6q 6261 5 acute acute JJ cord-006870-f5w6fw6q 6261 6 renal renal JJ cord-006870-f5w6fw6q 6261 7 failure failure NN cord-006870-f5w6fw6q 6261 8 requiring require VBG cord-006870-f5w6fw6q 6261 9 continuous continuous JJ cord-006870-f5w6fw6q 6261 10 renal renal JJ cord-006870-f5w6fw6q 6261 11 replacement replacement NN cord-006870-f5w6fw6q 6261 12 therapy therapy NN cord-006870-f5w6fw6q 6261 13 ( ( -LRB- cord-006870-f5w6fw6q 6261 14 CRRT CRRT NNP cord-006870-f5w6fw6q 6261 15 ) ) -RRB- cord-006870-f5w6fw6q 6261 16 . . . cord-006870-f5w6fw6q 6262 1 She -PRON- PRP cord-006870-f5w6fw6q 6262 2 had have VBD cord-006870-f5w6fw6q 6262 3 an an DT cord-006870-f5w6fw6q 6262 4 episode episode NN cord-006870-f5w6fw6q 6262 5 of of IN cord-006870-f5w6fw6q 6262 6 hypotension hypotension NN cord-006870-f5w6fw6q 6262 7 with with IN cord-006870-f5w6fw6q 6262 8 bradycardia bradycardia NN cord-006870-f5w6fw6q 6262 9 . . . cord-006870-f5w6fw6q 6263 1 Subsequently subsequently RB cord-006870-f5w6fw6q 6263 2 , , , cord-006870-f5w6fw6q 6263 3 her -PRON- PRP$ cord-006870-f5w6fw6q 6263 4 pupils pupil NNS cord-006870-f5w6fw6q 6263 5 were be VBD cord-006870-f5w6fw6q 6263 6 noted note VBN cord-006870-f5w6fw6q 6263 7 to to TO cord-006870-f5w6fw6q 6263 8 be be VB cord-006870-f5w6fw6q 6263 9 fixed fix VBN cord-006870-f5w6fw6q 6263 10 and and CC cord-006870-f5w6fw6q 6263 11 dilated dilated JJ cord-006870-f5w6fw6q 6263 12 . . . cord-006870-f5w6fw6q 6264 1 A a DT cord-006870-f5w6fw6q 6264 2 stat stat NN cord-006870-f5w6fw6q 6264 3 CT CT NNP cord-006870-f5w6fw6q 6264 4 head head NN cord-006870-f5w6fw6q 6264 5 then then RB cord-006870-f5w6fw6q 6264 6 showed show VBD cord-006870-f5w6fw6q 6264 7 diffuse diffuse JJ cord-006870-f5w6fw6q 6264 8 bilateral bilateral JJ cord-006870-f5w6fw6q 6264 9 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 6264 10 at at IN cord-006870-f5w6fw6q 6264 11 the the DT cord-006870-f5w6fw6q 6264 12 graywhite graywhite NNP cord-006870-f5w6fw6q 6264 13 junction junction NN cord-006870-f5w6fw6q 6264 14 as as RB cord-006870-f5w6fw6q 6264 15 well well RB cord-006870-f5w6fw6q 6264 16 as as IN cord-006870-f5w6fw6q 6264 17 diffuse diffuse JJ cord-006870-f5w6fw6q 6264 18 edema edema NN cord-006870-f5w6fw6q 6264 19 . . . cord-006870-f5w6fw6q 6265 1 Labs lab NNS cord-006870-f5w6fw6q 6265 2 showed show VBD cord-006870-f5w6fw6q 6265 3 thrombocytopenia thrombocytopenia NN cord-006870-f5w6fw6q 6265 4 likely likely RB cord-006870-f5w6fw6q 6265 5 due due IN cord-006870-f5w6fw6q 6265 6 to to IN cord-006870-f5w6fw6q 6265 7 disseminated disseminate VBN cord-006870-f5w6fw6q 6265 8 intravascular intravascular JJ cord-006870-f5w6fw6q 6265 9 coagulation coagulation NN cord-006870-f5w6fw6q 6265 10 ( ( -LRB- cord-006870-f5w6fw6q 6265 11 DIC DIC NNP cord-006870-f5w6fw6q 6265 12 ) ) -RRB- cord-006870-f5w6fw6q 6265 13 . . . cord-006870-f5w6fw6q 6266 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6266 2 exam exam NN cord-006870-f5w6fw6q 6266 3 was be VBD cord-006870-f5w6fw6q 6266 4 consistent consistent JJ cord-006870-f5w6fw6q 6266 5 with with IN cord-006870-f5w6fw6q 6266 6 brain brain NN cord-006870-f5w6fw6q 6266 7 death death NN cord-006870-f5w6fw6q 6266 8 . . . cord-006870-f5w6fw6q 6267 1 It -PRON- PRP cord-006870-f5w6fw6q 6267 2 has have VBZ cord-006870-f5w6fw6q 6267 3 been be VBN cord-006870-f5w6fw6q 6267 4 estimated estimate VBN cord-006870-f5w6fw6q 6267 5 that that IN cord-006870-f5w6fw6q 6267 6 up up IN cord-006870-f5w6fw6q 6267 7 to to TO cord-006870-f5w6fw6q 6267 8 90 90 CD cord-006870-f5w6fw6q 6267 9 % % NN cord-006870-f5w6fw6q 6267 10 of of IN cord-006870-f5w6fw6q 6267 11 patients patient NNS cord-006870-f5w6fw6q 6267 12 who who WP cord-006870-f5w6fw6q 6267 13 were be VBD cord-006870-f5w6fw6q 6267 14 placed place VBN cord-006870-f5w6fw6q 6267 15 on on IN cord-006870-f5w6fw6q 6267 16 ECMO ECMO NNP cord-006870-f5w6fw6q 6267 17 as as IN cord-006870-f5w6fw6q 6267 18 a a DT cord-006870-f5w6fw6q 6267 19 last last JJ cord-006870-f5w6fw6q 6267 20 resort resort NN cord-006870-f5w6fw6q 6267 21 for for IN cord-006870-f5w6fw6q 6267 22 respiratory respiratory JJ cord-006870-f5w6fw6q 6267 23 failure failure NN cord-006870-f5w6fw6q 6267 24 have have VBP cord-006870-f5w6fw6q 6267 25 neurological neurological JJ cord-006870-f5w6fw6q 6267 26 complications complication NNS cord-006870-f5w6fw6q 6267 27 including include VBG cord-006870-f5w6fw6q 6267 28 ICH ICH NNP cord-006870-f5w6fw6q 6267 29 . . . cord-006870-f5w6fw6q 6268 1 There there EX cord-006870-f5w6fw6q 6268 2 is be VBZ cord-006870-f5w6fw6q 6268 3 no no DT cord-006870-f5w6fw6q 6268 4 stereotypical stereotypical JJ cord-006870-f5w6fw6q 6268 5 pattern pattern NN cord-006870-f5w6fw6q 6268 6 of of IN cord-006870-f5w6fw6q 6268 7 bleeding bleed VBG cord-006870-f5w6fw6q 6268 8 but but CC cord-006870-f5w6fw6q 6268 9 diffuse diffuse JJ cord-006870-f5w6fw6q 6268 10 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6268 11 has have VBZ cord-006870-f5w6fw6q 6268 12 been be VBN cord-006870-f5w6fw6q 6268 13 seen see VBN cord-006870-f5w6fw6q 6268 14 , , , cord-006870-f5w6fw6q 6268 15 which which WDT cord-006870-f5w6fw6q 6268 16 is be VBZ cord-006870-f5w6fw6q 6268 17 consistent consistent JJ cord-006870-f5w6fw6q 6268 18 with with IN cord-006870-f5w6fw6q 6268 19 the the DT cord-006870-f5w6fw6q 6268 20 pattern pattern NN cord-006870-f5w6fw6q 6268 21 seen see VBN cord-006870-f5w6fw6q 6268 22 in in IN cord-006870-f5w6fw6q 6268 23 our -PRON- PRP$ cord-006870-f5w6fw6q 6268 24 patient patient NN cord-006870-f5w6fw6q 6268 25 . . . cord-006870-f5w6fw6q 6269 1 Notably notably RB cord-006870-f5w6fw6q 6269 2 , , , cord-006870-f5w6fw6q 6269 3 those those DT cord-006870-f5w6fw6q 6269 4 with with IN cord-006870-f5w6fw6q 6269 5 ICH ICH NNP cord-006870-f5w6fw6q 6269 6 have have VBP cord-006870-f5w6fw6q 6269 7 significantly significantly RB cord-006870-f5w6fw6q 6269 8 higher high JJR cord-006870-f5w6fw6q 6269 9 rates rate NNS cord-006870-f5w6fw6q 6269 10 of of IN cord-006870-f5w6fw6q 6269 11 mortality mortality NN cord-006870-f5w6fw6q 6269 12 . . . cord-006870-f5w6fw6q 6270 1 Thrombocytopenia Thrombocytopenia NNP cord-006870-f5w6fw6q 6270 2 , , , cord-006870-f5w6fw6q 6270 3 DIC DIC NNP cord-006870-f5w6fw6q 6270 4 , , , cord-006870-f5w6fw6q 6270 5 and and CC cord-006870-f5w6fw6q 6270 6 platelet platelet NN cord-006870-f5w6fw6q 6270 7 dysfunction dysfunction NN cord-006870-f5w6fw6q 6270 8 that that WDT cord-006870-f5w6fw6q 6270 9 develop develop VBP cord-006870-f5w6fw6q 6270 10 as as IN cord-006870-f5w6fw6q 6270 11 a a DT cord-006870-f5w6fw6q 6270 12 result result NN cord-006870-f5w6fw6q 6270 13 of of IN cord-006870-f5w6fw6q 6270 14 ECMO ECMO NNP cord-006870-f5w6fw6q 6270 15 are be VBP cord-006870-f5w6fw6q 6270 16 thought think VBN cord-006870-f5w6fw6q 6270 17 to to TO cord-006870-f5w6fw6q 6270 18 play play VB cord-006870-f5w6fw6q 6270 19 a a DT cord-006870-f5w6fw6q 6270 20 role role NN cord-006870-f5w6fw6q 6270 21 in in IN cord-006870-f5w6fw6q 6270 22 the the DT cord-006870-f5w6fw6q 6270 23 development development NN cord-006870-f5w6fw6q 6270 24 of of IN cord-006870-f5w6fw6q 6270 25 ICH ICH NNP cord-006870-f5w6fw6q 6270 26 . . . cord-006870-f5w6fw6q 6271 1 To to TO cord-006870-f5w6fw6q 6271 2 present present VB cord-006870-f5w6fw6q 6271 3 a a DT cord-006870-f5w6fw6q 6271 4 case case NN cord-006870-f5w6fw6q 6271 5 report report NN cord-006870-f5w6fw6q 6271 6 of of IN cord-006870-f5w6fw6q 6271 7 syndrome syndrome NN cord-006870-f5w6fw6q 6271 8 of of IN cord-006870-f5w6fw6q 6271 9 the the DT cord-006870-f5w6fw6q 6271 10 trepheined trepheined JJ cord-006870-f5w6fw6q 6271 11 ( ( -LRB- cord-006870-f5w6fw6q 6271 12 SoT SoT NNP cord-006870-f5w6fw6q 6271 13 ) ) -RRB- cord-006870-f5w6fw6q 6271 14 and and CC cord-006870-f5w6fw6q 6271 15 paradoxical paradoxical JJ cord-006870-f5w6fw6q 6271 16 herniation herniation NN cord-006870-f5w6fw6q 6271 17 without without IN cord-006870-f5w6fw6q 6271 18 craniectomy craniectomy NNP cord-006870-f5w6fw6q 6271 19 . . . cord-006870-f5w6fw6q 6272 1 SoT SoT NNP cord-006870-f5w6fw6q 6272 2 is be VBZ cord-006870-f5w6fw6q 6272 3 reported report VBN cord-006870-f5w6fw6q 6272 4 when when WRB cord-006870-f5w6fw6q 6272 5 a a DT cord-006870-f5w6fw6q 6272 6 constellation constellation NN cord-006870-f5w6fw6q 6272 7 of of IN cord-006870-f5w6fw6q 6272 8 positional positional JJ cord-006870-f5w6fw6q 6272 9 neurological neurological JJ cord-006870-f5w6fw6q 6272 10 symptoms symptom NNS cord-006870-f5w6fw6q 6272 11 arise arise VBP cord-006870-f5w6fw6q 6272 12 following follow VBG cord-006870-f5w6fw6q 6272 13 large large JJ cord-006870-f5w6fw6q 6272 14 craniectomy craniectomy NN cord-006870-f5w6fw6q 6272 15 , , , cord-006870-f5w6fw6q 6272 16 resolving resolve VBG cord-006870-f5w6fw6q 6272 17 in in IN cord-006870-f5w6fw6q 6272 18 a a DT cord-006870-f5w6fw6q 6272 19 delayed delay VBN cord-006870-f5w6fw6q 6272 20 fashion fashion NN cord-006870-f5w6fw6q 6272 21 following follow VBG cord-006870-f5w6fw6q 6272 22 cranioplasty cranioplasty NNP cord-006870-f5w6fw6q 6272 23 . . . cord-006870-f5w6fw6q 6273 1 Paradoxical paradoxical JJ cord-006870-f5w6fw6q 6273 2 herniation herniation NN cord-006870-f5w6fw6q 6273 3 may may MD cord-006870-f5w6fw6q 6273 4 occur occur VB cord-006870-f5w6fw6q 6273 5 in in IN cord-006870-f5w6fw6q 6273 6 extreme extreme JJ cord-006870-f5w6fw6q 6273 7 cases case NNS cord-006870-f5w6fw6q 6273 8 . . . cord-006870-f5w6fw6q 6274 1 The the DT cord-006870-f5w6fw6q 6274 2 pathophysiology pathophysiology NN cord-006870-f5w6fw6q 6274 3 is be VBZ cord-006870-f5w6fw6q 6274 4 incompletely incompletely RB cord-006870-f5w6fw6q 6274 5 understood understand VBN cord-006870-f5w6fw6q 6274 6 however however RB cord-006870-f5w6fw6q 6274 7 proposed propose VBN cord-006870-f5w6fw6q 6274 8 mechanisms mechanism NNS cord-006870-f5w6fw6q 6274 9 include include VBP cord-006870-f5w6fw6q 6274 10 compression compression NN cord-006870-f5w6fw6q 6274 11 of of IN cord-006870-f5w6fw6q 6274 12 underlying underlie VBG cord-006870-f5w6fw6q 6274 13 brain brain NN cord-006870-f5w6fw6q 6274 14 by by IN cord-006870-f5w6fw6q 6274 15 the the DT cord-006870-f5w6fw6q 6274 16 flaccid flaccid JJ cord-006870-f5w6fw6q 6274 17 skin skin NN cord-006870-f5w6fw6q 6274 18 flap flap NN cord-006870-f5w6fw6q 6274 19 due due IN cord-006870-f5w6fw6q 6274 20 to to IN cord-006870-f5w6fw6q 6274 21 the the DT cord-006870-f5w6fw6q 6274 22 gradient gradient NN cord-006870-f5w6fw6q 6274 23 between between IN cord-006870-f5w6fw6q 6274 24 atmospheric atmospheric JJ cord-006870-f5w6fw6q 6274 25 and and CC cord-006870-f5w6fw6q 6274 26 intracranial intracranial JJ cord-006870-f5w6fw6q 6274 27 pressure pressure NN cord-006870-f5w6fw6q 6274 28 exacerbated exacerbate VBN cord-006870-f5w6fw6q 6274 29 by by IN cord-006870-f5w6fw6q 6274 30 upright upright JJ cord-006870-f5w6fw6q 6274 31 pressure pressure NN cord-006870-f5w6fw6q 6274 32 , , , cord-006870-f5w6fw6q 6274 33 changes change NNS cord-006870-f5w6fw6q 6274 34 in in IN cord-006870-f5w6fw6q 6274 35 cerebral cerebral JJ cord-006870-f5w6fw6q 6274 36 blood blood NN cord-006870-f5w6fw6q 6274 37 flow flow NN cord-006870-f5w6fw6q 6274 38 , , , cord-006870-f5w6fw6q 6274 39 and and CC cord-006870-f5w6fw6q 6274 40 CSF CSF NNP cord-006870-f5w6fw6q 6274 41 fluid fluid NN cord-006870-f5w6fw6q 6274 42 . . . cord-006870-f5w6fw6q 6275 1 A a DT cord-006870-f5w6fw6q 6275 2 middle middle JJ cord-006870-f5w6fw6q 6275 3 aged aged JJ cord-006870-f5w6fw6q 6275 4 woman woman NN cord-006870-f5w6fw6q 6275 5 with with IN cord-006870-f5w6fw6q 6275 6 a a DT cord-006870-f5w6fw6q 6275 7 history history NN cord-006870-f5w6fw6q 6275 8 of of IN cord-006870-f5w6fw6q 6275 9 mood mood NN cord-006870-f5w6fw6q 6275 10 changes change VBZ cord-006870-f5w6fw6q 6275 11 eight eight CD cord-006870-f5w6fw6q 6275 12 months month NNS cord-006870-f5w6fw6q 6275 13 preceding precede VBG cord-006870-f5w6fw6q 6275 14 admission admission NN cord-006870-f5w6fw6q 6275 15 presents present VBZ cord-006870-f5w6fw6q 6275 16 with with IN cord-006870-f5w6fw6q 6275 17 worsening worsen VBG cord-006870-f5w6fw6q 6275 18 left left JJ cord-006870-f5w6fw6q 6275 19 hemiplegia hemiplegia NN cord-006870-f5w6fw6q 6275 20 over over IN cord-006870-f5w6fw6q 6275 21 one one CD cord-006870-f5w6fw6q 6275 22 week week NN cord-006870-f5w6fw6q 6275 23 . . . cord-006870-f5w6fw6q 6276 1 MRI MRI NNP cord-006870-f5w6fw6q 6276 2 revealed reveal VBD cord-006870-f5w6fw6q 6276 3 a a DT cord-006870-f5w6fw6q 6276 4 78 78 CD cord-006870-f5w6fw6q 6276 5 x x SYM cord-006870-f5w6fw6q 6276 6 44 44 CD cord-006870-f5w6fw6q 6276 7 mm mm NNP cord-006870-f5w6fw6q 6276 8 right right JJ cord-006870-f5w6fw6q 6276 9 frontal frontal JJ cord-006870-f5w6fw6q 6276 10 cystic cystic JJ cord-006870-f5w6fw6q 6276 11 mass mass NN cord-006870-f5w6fw6q 6276 12 . . . cord-006870-f5w6fw6q 6277 1 Hyperosmolar Hyperosmolar NNP cord-006870-f5w6fw6q 6277 2 therapy therapy NN cord-006870-f5w6fw6q 6277 3 and and CC cord-006870-f5w6fw6q 6277 4 steroids steroid NNS cord-006870-f5w6fw6q 6277 5 were be VBD cord-006870-f5w6fw6q 6277 6 initiated initiate VBN cord-006870-f5w6fw6q 6277 7 for for IN cord-006870-f5w6fw6q 6277 8 midline midline JJ cord-006870-f5w6fw6q 6277 9 shift shift NN cord-006870-f5w6fw6q 6277 10 and and CC cord-006870-f5w6fw6q 6277 11 brainstem brainstem NN cord-006870-f5w6fw6q 6277 12 compression compression NN cord-006870-f5w6fw6q 6277 13 . . . cord-006870-f5w6fw6q 6278 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6278 2 immediate immediate JJ cord-006870-f5w6fw6q 6278 3 post post JJ cord-006870-f5w6fw6q 6278 4 operative operative NN cord-006870-f5w6fw6q 6278 5 course course NN cord-006870-f5w6fw6q 6278 6 after after IN cord-006870-f5w6fw6q 6278 7 tumour tumour NN cord-006870-f5w6fw6q 6278 8 excision excision NN cord-006870-f5w6fw6q 6278 9 was be VBD cord-006870-f5w6fw6q 6278 10 uncomplicated uncomplicated JJ cord-006870-f5w6fw6q 6278 11 . . . cord-006870-f5w6fw6q 6279 1 On on IN cord-006870-f5w6fw6q 6279 2 post post JJ cord-006870-f5w6fw6q 6279 3 - - JJ cord-006870-f5w6fw6q 6279 4 operative operative JJ cord-006870-f5w6fw6q 6279 5 day day NN cord-006870-f5w6fw6q 6279 6 two two CD cord-006870-f5w6fw6q 6279 7 , , , cord-006870-f5w6fw6q 6279 8 she -PRON- PRP cord-006870-f5w6fw6q 6279 9 developed develop VBD cord-006870-f5w6fw6q 6279 10 uncontrolled uncontrolled JJ cord-006870-f5w6fw6q 6279 11 hypertension hypertension NN cord-006870-f5w6fw6q 6279 12 , , , cord-006870-f5w6fw6q 6279 13 worsening worsen VBG cord-006870-f5w6fw6q 6279 14 anisocoria anisocoria NN cord-006870-f5w6fw6q 6279 15 , , , cord-006870-f5w6fw6q 6279 16 and and CC cord-006870-f5w6fw6q 6279 17 decerebrate decerebrate JJ cord-006870-f5w6fw6q 6279 18 posturing posturing NN cord-006870-f5w6fw6q 6279 19 requiring require VBG cord-006870-f5w6fw6q 6279 20 urgent urgent JJ cord-006870-f5w6fw6q 6279 21 intubation intubation NN cord-006870-f5w6fw6q 6279 22 . . . cord-006870-f5w6fw6q 6280 1 Head Head NNP cord-006870-f5w6fw6q 6280 2 CT CT NNP cord-006870-f5w6fw6q 6280 3 revealed reveal VBD cord-006870-f5w6fw6q 6280 4 uncal uncal JJ cord-006870-f5w6fw6q 6280 5 and and CC cord-006870-f5w6fw6q 6280 6 subfalcine subfalcine NNP cord-006870-f5w6fw6q 6280 7 herniation herniation NN cord-006870-f5w6fw6q 6280 8 despite despite IN cord-006870-f5w6fw6q 6280 9 a a DT cord-006870-f5w6fw6q 6280 10 large large JJ cord-006870-f5w6fw6q 6280 11 resection resection NN cord-006870-f5w6fw6q 6280 12 cavity cavity NN cord-006870-f5w6fw6q 6280 13 . . . cord-006870-f5w6fw6q 6281 1 An an DT cord-006870-f5w6fw6q 6281 2 external external JJ cord-006870-f5w6fw6q 6281 3 ventricular ventricular JJ cord-006870-f5w6fw6q 6281 4 drain drain NN cord-006870-f5w6fw6q 6281 5 was be VBD cord-006870-f5w6fw6q 6281 6 placed place VBN cord-006870-f5w6fw6q 6281 7 and and CC cord-006870-f5w6fw6q 6281 8 removed remove VBN cord-006870-f5w6fw6q 6281 9 due due IN cord-006870-f5w6fw6q 6281 10 to to IN cord-006870-f5w6fw6q 6281 11 lack lack NN cord-006870-f5w6fw6q 6281 12 of of IN cord-006870-f5w6fw6q 6281 13 drainage drainage NN cord-006870-f5w6fw6q 6281 14 . . . cord-006870-f5w6fw6q 6282 1 Within within IN cord-006870-f5w6fw6q 6282 2 12 12 CD cord-006870-f5w6fw6q 6282 3 hours hour NNS cord-006870-f5w6fw6q 6282 4 of of IN cord-006870-f5w6fw6q 6282 5 Trendelenburg Trendelenburg NNP cord-006870-f5w6fw6q 6282 6 positioning positioning NN cord-006870-f5w6fw6q 6282 7 , , , cord-006870-f5w6fw6q 6282 8 she -PRON- PRP cord-006870-f5w6fw6q 6282 9 improved improve VBD cord-006870-f5w6fw6q 6282 10 both both CC cord-006870-f5w6fw6q 6282 11 clinically clinically RB cord-006870-f5w6fw6q 6282 12 and and CC cord-006870-f5w6fw6q 6282 13 radiographically radiographically RB cord-006870-f5w6fw6q 6282 14 . . . cord-006870-f5w6fw6q 6283 1 She -PRON- PRP cord-006870-f5w6fw6q 6283 2 did do VBD cord-006870-f5w6fw6q 6283 3 not not RB cord-006870-f5w6fw6q 6283 4 undergo undergo VB cord-006870-f5w6fw6q 6283 5 an an DT cord-006870-f5w6fw6q 6283 6 intraoperative intraoperative JJ cord-006870-f5w6fw6q 6283 7 CSF CSF NNP cord-006870-f5w6fw6q 6283 8 reduction reduction NN cord-006870-f5w6fw6q 6283 9 and and CC cord-006870-f5w6fw6q 6283 10 no no DT cord-006870-f5w6fw6q 6283 11 preadmission preadmission NN cord-006870-f5w6fw6q 6283 12 history history NN cord-006870-f5w6fw6q 6283 13 ( ( -LRB- cord-006870-f5w6fw6q 6283 14 back back JJ cord-006870-f5w6fw6q 6283 15 pain pain NN cord-006870-f5w6fw6q 6283 16 , , , cord-006870-f5w6fw6q 6283 17 orthostatic orthostatic JJ cord-006870-f5w6fw6q 6283 18 headache headache NN cord-006870-f5w6fw6q 6283 19 , , , cord-006870-f5w6fw6q 6283 20 trauma trauma NN cord-006870-f5w6fw6q 6283 21 ) ) -RRB- cord-006870-f5w6fw6q 6283 22 to to TO cord-006870-f5w6fw6q 6283 23 support support VB cord-006870-f5w6fw6q 6283 24 an an DT cord-006870-f5w6fw6q 6283 25 occult occult JJ cord-006870-f5w6fw6q 6283 26 CSF CSF NNP cord-006870-f5w6fw6q 6283 27 leak leak NN cord-006870-f5w6fw6q 6283 28 . . . cord-006870-f5w6fw6q 6284 1 She -PRON- PRP cord-006870-f5w6fw6q 6284 2 had have VBD cord-006870-f5w6fw6q 6284 3 a a DT cord-006870-f5w6fw6q 6284 4 recurrence recurrence NN cord-006870-f5w6fw6q 6284 5 of of IN cord-006870-f5w6fw6q 6284 6 symptoms symptom NNS cord-006870-f5w6fw6q 6284 7 on on IN cord-006870-f5w6fw6q 6284 8 post post JJ cord-006870-f5w6fw6q 6284 9 - - JJ cord-006870-f5w6fw6q 6284 10 operative operative JJ cord-006870-f5w6fw6q 6284 11 day day NN cord-006870-f5w6fw6q 6284 12 eight eight CD cord-006870-f5w6fw6q 6284 13 which which WDT cord-006870-f5w6fw6q 6284 14 also also RB cord-006870-f5w6fw6q 6284 15 resolved resolve VBD cord-006870-f5w6fw6q 6284 16 upon upon IN cord-006870-f5w6fw6q 6284 17 lying lie VBG cord-006870-f5w6fw6q 6284 18 flat flat JJ cord-006870-f5w6fw6q 6284 19 for for IN cord-006870-f5w6fw6q 6284 20 48 48 CD cord-006870-f5w6fw6q 6284 21 hours hour NNS cord-006870-f5w6fw6q 6284 22 . . . cord-006870-f5w6fw6q 6285 1 She -PRON- PRP cord-006870-f5w6fw6q 6285 2 was be VBD cord-006870-f5w6fw6q 6285 3 ultimately ultimately RB cord-006870-f5w6fw6q 6285 4 discharged discharge VBN cord-006870-f5w6fw6q 6285 5 to to IN cord-006870-f5w6fw6q 6285 6 acute acute JJ cord-006870-f5w6fw6q 6285 7 rehab rehab NN cord-006870-f5w6fw6q 6285 8 and and CC cord-006870-f5w6fw6q 6285 9 tumor tumor NN cord-006870-f5w6fw6q 6285 10 pathology pathology NN cord-006870-f5w6fw6q 6285 11 returned return VBD cord-006870-f5w6fw6q 6285 12 as as IN cord-006870-f5w6fw6q 6285 13 glioblastoma glioblastoma NN cord-006870-f5w6fw6q 6285 14 ( ( -LRB- cord-006870-f5w6fw6q 6285 15 WHO who WP cord-006870-f5w6fw6q 6285 16 grade grade NN cord-006870-f5w6fw6q 6285 17 4 4 CD cord-006870-f5w6fw6q 6285 18 ) ) -RRB- cord-006870-f5w6fw6q 6285 19 . . . cord-006870-f5w6fw6q 6286 1 This this DT cord-006870-f5w6fw6q 6286 2 novel novel JJ cord-006870-f5w6fw6q 6286 3 case case NN cord-006870-f5w6fw6q 6286 4 of of IN cord-006870-f5w6fw6q 6286 5 SoT SoT NNP cord-006870-f5w6fw6q 6286 6 in in IN cord-006870-f5w6fw6q 6286 7 the the DT cord-006870-f5w6fw6q 6286 8 absence absence NN cord-006870-f5w6fw6q 6286 9 of of IN cord-006870-f5w6fw6q 6286 10 craniectomy craniectomy NN cord-006870-f5w6fw6q 6286 11 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 6286 12 the the DT cord-006870-f5w6fw6q 6286 13 complex complex JJ cord-006870-f5w6fw6q 6286 14 and and CC cord-006870-f5w6fw6q 6286 15 poorly poorly RB cord-006870-f5w6fw6q 6286 16 understood understand VBD cord-006870-f5w6fw6q 6286 17 consequences consequence NNS cord-006870-f5w6fw6q 6286 18 of of IN cord-006870-f5w6fw6q 6286 19 slow slow JJ cord-006870-f5w6fw6q 6286 20 growing grow VBG cord-006870-f5w6fw6q 6286 21 massive massive JJ cord-006870-f5w6fw6q 6286 22 tumors tumor NNS cord-006870-f5w6fw6q 6286 23 , , , cord-006870-f5w6fw6q 6286 24 CSF csf NN cord-006870-f5w6fw6q 6286 25 dynamics dynamic NNS cord-006870-f5w6fw6q 6286 26 and and CC cord-006870-f5w6fw6q 6286 27 exertional exertional JJ cord-006870-f5w6fw6q 6286 28 force force NN cord-006870-f5w6fw6q 6286 29 on on IN cord-006870-f5w6fw6q 6286 30 static static JJ cord-006870-f5w6fw6q 6286 31 CNS CNS NNP cord-006870-f5w6fw6q 6286 32 structures structure NNS cord-006870-f5w6fw6q 6286 33 . . . cord-006870-f5w6fw6q 6287 1 This this DT cord-006870-f5w6fw6q 6287 2 case case NN cord-006870-f5w6fw6q 6287 3 also also RB cord-006870-f5w6fw6q 6287 4 illustrates illustrate VBZ cord-006870-f5w6fw6q 6287 5 the the DT cord-006870-f5w6fw6q 6287 6 benefits benefit NNS cord-006870-f5w6fw6q 6287 7 of of IN cord-006870-f5w6fw6q 6287 8 a a DT cord-006870-f5w6fw6q 6287 9 collaborative collaborative JJ cord-006870-f5w6fw6q 6287 10 , , , cord-006870-f5w6fw6q 6287 11 multidisciplinary multidisciplinary JJ cord-006870-f5w6fw6q 6287 12 approach approach NN cord-006870-f5w6fw6q 6287 13 to to IN cord-006870-f5w6fw6q 6287 14 patient patient JJ cord-006870-f5w6fw6q 6287 15 care care NN cord-006870-f5w6fw6q 6287 16 in in IN cord-006870-f5w6fw6q 6287 17 the the DT cord-006870-f5w6fw6q 6287 18 NeuroICU NeuroICU NNP cord-006870-f5w6fw6q 6287 19 . . . cord-006870-f5w6fw6q 6288 1 To to TO cord-006870-f5w6fw6q 6288 2 present present VB cord-006870-f5w6fw6q 6288 3 a a DT cord-006870-f5w6fw6q 6288 4 lesser lesser RBR cord-006870-f5w6fw6q 6288 5 known know VBN cord-006870-f5w6fw6q 6288 6 leukoencephalopathy leukoencephalopathy NNS cord-006870-f5w6fw6q 6288 7 that that WDT cord-006870-f5w6fw6q 6288 8 occurs occur VBZ cord-006870-f5w6fw6q 6288 9 when when WRB cord-006870-f5w6fw6q 6288 10 patients patient NNS cord-006870-f5w6fw6q 6288 11 overdose overdose VBP cord-006870-f5w6fw6q 6288 12 on on IN cord-006870-f5w6fw6q 6288 13 inhaled inhale VBN cord-006870-f5w6fw6q 6288 14 heroin heroin NN cord-006870-f5w6fw6q 6288 15 vapor vapor NN cord-006870-f5w6fw6q 6288 16 ' ' '' cord-006870-f5w6fw6q 6288 17 Chasing chase VBG cord-006870-f5w6fw6q 6288 18 the the DT cord-006870-f5w6fw6q 6288 19 dragon dragon NN cord-006870-f5w6fw6q 6288 20 " " `` cord-006870-f5w6fw6q 6288 21 is be VBZ cord-006870-f5w6fw6q 6288 22 a a DT cord-006870-f5w6fw6q 6288 23 method method NN cord-006870-f5w6fw6q 6288 24 of of IN cord-006870-f5w6fw6q 6288 25 inhaled inhale VBN cord-006870-f5w6fw6q 6288 26 heroin heroin NN cord-006870-f5w6fw6q 6288 27 vapor vapor NN cord-006870-f5w6fw6q 6288 28 that that WDT cord-006870-f5w6fw6q 6288 29 is be VBZ cord-006870-f5w6fw6q 6288 30 different different JJ cord-006870-f5w6fw6q 6288 31 from from IN cord-006870-f5w6fw6q 6288 32 smoking smoke VBG cord-006870-f5w6fw6q 6288 33 or or CC cord-006870-f5w6fw6q 6288 34 snorting snort VBG cord-006870-f5w6fw6q 6288 35 heroin heroin NN cord-006870-f5w6fw6q 6288 36 . . . cord-006870-f5w6fw6q 6289 1 Heroin heroin NN cord-006870-f5w6fw6q 6289 2 powder powder NN cord-006870-f5w6fw6q 6289 3 is be VBZ cord-006870-f5w6fw6q 6289 4 placed place VBN cord-006870-f5w6fw6q 6289 5 on on IN cord-006870-f5w6fw6q 6289 6 aluminum aluminum NN cord-006870-f5w6fw6q 6289 7 foil foil NN cord-006870-f5w6fw6q 6289 8 , , , cord-006870-f5w6fw6q 6289 9 which which WDT cord-006870-f5w6fw6q 6289 10 is be VBZ cord-006870-f5w6fw6q 6289 11 heated heat VBN cord-006870-f5w6fw6q 6289 12 by by IN cord-006870-f5w6fw6q 6289 13 placing place VBG cord-006870-f5w6fw6q 6289 14 a a DT cord-006870-f5w6fw6q 6289 15 flame flame NN cord-006870-f5w6fw6q 6289 16 underneath underneath RB cord-006870-f5w6fw6q 6289 17 . . . cord-006870-f5w6fw6q 6290 1 The the DT cord-006870-f5w6fw6q 6290 2 white white JJ cord-006870-f5w6fw6q 6290 3 powder powder NN cord-006870-f5w6fw6q 6290 4 turns turn VBZ cord-006870-f5w6fw6q 6290 5 into into IN cord-006870-f5w6fw6q 6290 6 a a DT cord-006870-f5w6fw6q 6290 7 reddish reddish JJ cord-006870-f5w6fw6q 6290 8 - - HYPH cord-006870-f5w6fw6q 6290 9 brown brown JJ cord-006870-f5w6fw6q 6290 10 gelatinous gelatinous JJ cord-006870-f5w6fw6q 6290 11 substance substance NN cord-006870-f5w6fw6q 6290 12 that that WDT cord-006870-f5w6fw6q 6290 13 releases release VBZ cord-006870-f5w6fw6q 6290 14 a a DT cord-006870-f5w6fw6q 6290 15 thick thick JJ cord-006870-f5w6fw6q 6290 16 , , , cord-006870-f5w6fw6q 6290 17 white white JJ cord-006870-f5w6fw6q 6290 18 smoke smoke NN cord-006870-f5w6fw6q 6290 19 , , , cord-006870-f5w6fw6q 6290 20 which which WDT cord-006870-f5w6fw6q 6290 21 resembles resemble VBZ cord-006870-f5w6fw6q 6290 22 a a DT cord-006870-f5w6fw6q 6290 23 dragon dragon NN cord-006870-f5w6fw6q 6290 24 's 's POS cord-006870-f5w6fw6q 6290 25 tail tail NN cord-006870-f5w6fw6q 6290 26 . . . cord-006870-f5w6fw6q 6291 1 The the DT cord-006870-f5w6fw6q 6291 2 fumes fume NNS cord-006870-f5w6fw6q 6291 3 are be VBP cord-006870-f5w6fw6q 6291 4 " " `` cord-006870-f5w6fw6q 6291 5 chased chase VBN cord-006870-f5w6fw6q 6291 6 " " '' cord-006870-f5w6fw6q 6291 7 or or CC cord-006870-f5w6fw6q 6291 8 inhaled inhale VBN cord-006870-f5w6fw6q 6291 9 through through IN cord-006870-f5w6fw6q 6291 10 a a DT cord-006870-f5w6fw6q 6291 11 straw straw NN cord-006870-f5w6fw6q 6291 12 or or CC cord-006870-f5w6fw6q 6291 13 small small JJ cord-006870-f5w6fw6q 6291 14 tube tube NN cord-006870-f5w6fw6q 6291 15 . . . cord-006870-f5w6fw6q 6292 1 Currently currently RB cord-006870-f5w6fw6q 6292 2 the the DT cord-006870-f5w6fw6q 6292 3 US US NNP cord-006870-f5w6fw6q 6292 4 is be VBZ cord-006870-f5w6fw6q 6292 5 facing face VBG cord-006870-f5w6fw6q 6292 6 a a DT cord-006870-f5w6fw6q 6292 7 growing grow VBG cord-006870-f5w6fw6q 6292 8 epidemic epidemic NN cord-006870-f5w6fw6q 6292 9 of of IN cord-006870-f5w6fw6q 6292 10 heroin heroin NN cord-006870-f5w6fw6q 6292 11 use use NN cord-006870-f5w6fw6q 6292 12 making make VBG cord-006870-f5w6fw6q 6292 13 this this DT cord-006870-f5w6fw6q 6292 14 leukoencephalopathy leukoencephalopathy XX cord-006870-f5w6fw6q 6292 15 more more RBR cord-006870-f5w6fw6q 6292 16 pronounced pronounced JJ cord-006870-f5w6fw6q 6292 17 . . . cord-006870-f5w6fw6q 6293 1 A a DT cord-006870-f5w6fw6q 6293 2 34-year 34-year JJ cord-006870-f5w6fw6q 6293 3 - - HYPH cord-006870-f5w6fw6q 6293 4 old old JJ cord-006870-f5w6fw6q 6293 5 female female NN cord-006870-f5w6fw6q 6293 6 with with IN cord-006870-f5w6fw6q 6293 7 history history NN cord-006870-f5w6fw6q 6293 8 of of IN cord-006870-f5w6fw6q 6293 9 drug drug NN cord-006870-f5w6fw6q 6293 10 abuse abuse NN cord-006870-f5w6fw6q 6293 11 presented present VBN cord-006870-f5w6fw6q 6293 12 to to IN cord-006870-f5w6fw6q 6293 13 the the DT cord-006870-f5w6fw6q 6293 14 emergency emergency NN cord-006870-f5w6fw6q 6293 15 department department NN cord-006870-f5w6fw6q 6293 16 with with IN cord-006870-f5w6fw6q 6293 17 altered alter VBN cord-006870-f5w6fw6q 6293 18 mental mental JJ cord-006870-f5w6fw6q 6293 19 status status NN cord-006870-f5w6fw6q 6293 20 . . . cord-006870-f5w6fw6q 6294 1 The the DT cord-006870-f5w6fw6q 6294 2 boyfriend boyfriend NN cord-006870-f5w6fw6q 6294 3 informed inform VBD cord-006870-f5w6fw6q 6294 4 staff staff NN cord-006870-f5w6fw6q 6294 5 that that IN cord-006870-f5w6fw6q 6294 6 she -PRON- PRP cord-006870-f5w6fw6q 6294 7 likely likely RB cord-006870-f5w6fw6q 6294 8 smoked smoke VBD cord-006870-f5w6fw6q 6294 9 heroin heroin NN cord-006870-f5w6fw6q 6294 10 . . . cord-006870-f5w6fw6q 6295 1 On on IN cord-006870-f5w6fw6q 6295 2 arrival arrival NN cord-006870-f5w6fw6q 6295 3 , , , cord-006870-f5w6fw6q 6295 4 she -PRON- PRP cord-006870-f5w6fw6q 6295 5 was be VBD cord-006870-f5w6fw6q 6295 6 drowsy drowsy JJ cord-006870-f5w6fw6q 6295 7 but but CC cord-006870-f5w6fw6q 6295 8 easily easily RB cord-006870-f5w6fw6q 6295 9 arousable arousable JJ cord-006870-f5w6fw6q 6295 10 . . . cord-006870-f5w6fw6q 6296 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6296 2 brainstem brainstem NN cord-006870-f5w6fw6q 6296 3 reflexes reflex NNS cord-006870-f5w6fw6q 6296 4 were be VBD cord-006870-f5w6fw6q 6296 5 intact intact JJ cord-006870-f5w6fw6q 6297 1 but but CC cord-006870-f5w6fw6q 6297 2 she -PRON- PRP cord-006870-f5w6fw6q 6297 3 was be VBD cord-006870-f5w6fw6q 6297 4 grossly grossly RB cord-006870-f5w6fw6q 6297 5 dysmetric dysmetric JJ cord-006870-f5w6fw6q 6297 6 . . . cord-006870-f5w6fw6q 6298 1 Urine urine NN cord-006870-f5w6fw6q 6298 2 drug drug NN cord-006870-f5w6fw6q 6298 3 screen screen NN cord-006870-f5w6fw6q 6298 4 was be VBD cord-006870-f5w6fw6q 6298 5 positive positive JJ cord-006870-f5w6fw6q 6298 6 for for IN cord-006870-f5w6fw6q 6298 7 opiates opiate NNS cord-006870-f5w6fw6q 6298 8 only only RB cord-006870-f5w6fw6q 6298 9 . . . cord-006870-f5w6fw6q 6299 1 Initial initial JJ cord-006870-f5w6fw6q 6299 2 CT CT NNP cord-006870-f5w6fw6q 6299 3 of of IN cord-006870-f5w6fw6q 6299 4 the the DT cord-006870-f5w6fw6q 6299 5 brain brain NN cord-006870-f5w6fw6q 6299 6 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6299 7 extensive extensive JJ cord-006870-f5w6fw6q 6299 8 loss loss NN cord-006870-f5w6fw6q 6299 9 of of IN cord-006870-f5w6fw6q 6299 10 gray gray JJ cord-006870-f5w6fw6q 6299 11 - - HYPH cord-006870-f5w6fw6q 6299 12 white white JJ cord-006870-f5w6fw6q 6299 13 differentiation differentiation NN cord-006870-f5w6fw6q 6299 14 within within IN cord-006870-f5w6fw6q 6299 15 the the DT cord-006870-f5w6fw6q 6299 16 cerebellar cerebellar JJ cord-006870-f5w6fw6q 6299 17 hemispheres hemisphere NNS cord-006870-f5w6fw6q 6299 18 and and CC cord-006870-f5w6fw6q 6299 19 bilateral bilateral JJ cord-006870-f5w6fw6q 6299 20 lucency lucency NN cord-006870-f5w6fw6q 6299 21 in in IN cord-006870-f5w6fw6q 6299 22 the the DT cord-006870-f5w6fw6q 6299 23 globus globus NNP cord-006870-f5w6fw6q 6299 24 pallidus pallidus NNP cord-006870-f5w6fw6q 6299 25 and and CC cord-006870-f5w6fw6q 6299 26 developing develop VBG cord-006870-f5w6fw6q 6299 27 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 6299 28 . . . cord-006870-f5w6fw6q 6300 1 Patient Patient NNP cord-006870-f5w6fw6q 6300 2 was be VBD cord-006870-f5w6fw6q 6300 3 placed place VBN cord-006870-f5w6fw6q 6300 4 in in IN cord-006870-f5w6fw6q 6300 5 the the DT cord-006870-f5w6fw6q 6300 6 neurointensive neurointensive NNP cord-006870-f5w6fw6q 6300 7 care care NN cord-006870-f5w6fw6q 6300 8 unit unit NN cord-006870-f5w6fw6q 6300 9 to to TO cord-006870-f5w6fw6q 6300 10 monitor monitor VB cord-006870-f5w6fw6q 6300 11 and and CC cord-006870-f5w6fw6q 6300 12 was be VBD cord-006870-f5w6fw6q 6300 13 managed manage VBN cord-006870-f5w6fw6q 6300 14 medically medically RB cord-006870-f5w6fw6q 6300 15 with with IN cord-006870-f5w6fw6q 6300 16 hypertonic hypertonic JJ cord-006870-f5w6fw6q 6300 17 therapy therapy NN cord-006870-f5w6fw6q 6300 18 to to TO cord-006870-f5w6fw6q 6300 19 combat combat VB cord-006870-f5w6fw6q 6300 20 her -PRON- PRP$ cord-006870-f5w6fw6q 6300 21 cerebral cerebral JJ cord-006870-f5w6fw6q 6300 22 edema edema NN cord-006870-f5w6fw6q 6300 23 . . . cord-006870-f5w6fw6q 6301 1 An an DT cord-006870-f5w6fw6q 6301 2 MRI MRI NNP cord-006870-f5w6fw6q 6301 3 was be VBD cord-006870-f5w6fw6q 6301 4 done do VBN cord-006870-f5w6fw6q 6301 5 which which WDT cord-006870-f5w6fw6q 6301 6 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6301 7 a a DT cord-006870-f5w6fw6q 6301 8 distinctive distinctive JJ cord-006870-f5w6fw6q 6301 9 pattern pattern NN cord-006870-f5w6fw6q 6301 10 of of IN cord-006870-f5w6fw6q 6301 11 symmetrical symmetrical JJ cord-006870-f5w6fw6q 6301 12 white white JJ cord-006870-f5w6fw6q 6301 13 matter matter NN cord-006870-f5w6fw6q 6301 14 T2 T2 NNP cord-006870-f5w6fw6q 6301 15 hyperintensities hyperintensitie NNS cord-006870-f5w6fw6q 6301 16 in in IN cord-006870-f5w6fw6q 6301 17 the the DT cord-006870-f5w6fw6q 6301 18 cerebellum cerebellum NN cord-006870-f5w6fw6q 6301 19 , , , cord-006870-f5w6fw6q 6301 20 hippocampus hippocampus NN cord-006870-f5w6fw6q 6301 21 and and CC cord-006870-f5w6fw6q 6301 22 internal internal JJ cord-006870-f5w6fw6q 6301 23 capsule capsule NN cord-006870-f5w6fw6q 6301 24 bilaterally bilaterally RB cord-006870-f5w6fw6q 6301 25 characteristically characteristically RB cord-006870-f5w6fw6q 6301 26 known know VBN cord-006870-f5w6fw6q 6301 27 as as IN cord-006870-f5w6fw6q 6301 28 " " `` cord-006870-f5w6fw6q 6301 29 chasing chase VBG cord-006870-f5w6fw6q 6301 30 the the DT cord-006870-f5w6fw6q 6301 31 dragon dragon NN cord-006870-f5w6fw6q 6301 32 " " '' cord-006870-f5w6fw6q 6301 33 sign sign NN cord-006870-f5w6fw6q 6301 34 . . . cord-006870-f5w6fw6q 6302 1 The the DT cord-006870-f5w6fw6q 6302 2 patient patient NN cord-006870-f5w6fw6q 6302 3 gradually gradually RB cord-006870-f5w6fw6q 6302 4 improved improve VBD cord-006870-f5w6fw6q 6302 5 with with IN cord-006870-f5w6fw6q 6302 6 supportive supportive JJ cord-006870-f5w6fw6q 6302 7 treatment treatment NN cord-006870-f5w6fw6q 6302 8 , , , cord-006870-f5w6fw6q 6302 9 but but CC cord-006870-f5w6fw6q 6302 10 continued continue VBD cord-006870-f5w6fw6q 6302 11 to to TO cord-006870-f5w6fw6q 6302 12 have have VB cord-006870-f5w6fw6q 6302 13 mild mild JJ cord-006870-f5w6fw6q 6302 14 ataxia ataxia NN cord-006870-f5w6fw6q 6302 15 upon upon IN cord-006870-f5w6fw6q 6302 16 discharge discharge NN cord-006870-f5w6fw6q 6302 17 . . . cord-006870-f5w6fw6q 6303 1 We -PRON- PRP cord-006870-f5w6fw6q 6303 2 present present VBP cord-006870-f5w6fw6q 6303 3 a a DT cord-006870-f5w6fw6q 6303 4 case case NN cord-006870-f5w6fw6q 6303 5 of of IN cord-006870-f5w6fw6q 6303 6 leukoencephalopathy leukoencephalopathy NNP cord-006870-f5w6fw6q 6303 7 that that WDT cord-006870-f5w6fw6q 6303 8 was be VBD cord-006870-f5w6fw6q 6303 9 generally generally RB cord-006870-f5w6fw6q 6303 10 rare rare JJ cord-006870-f5w6fw6q 6303 11 to to TO cord-006870-f5w6fw6q 6303 12 see see VB cord-006870-f5w6fw6q 6303 13 , , , cord-006870-f5w6fw6q 6303 14 but but CC cord-006870-f5w6fw6q 6303 15 now now RB cord-006870-f5w6fw6q 6303 16 that that DT cord-006870-f5w6fw6q 6303 17 heroin heroin NN cord-006870-f5w6fw6q 6303 18 use use NN cord-006870-f5w6fw6q 6303 19 is be VBZ cord-006870-f5w6fw6q 6303 20 now now RB cord-006870-f5w6fw6q 6303 21 at at IN cord-006870-f5w6fw6q 6303 22 a a DT cord-006870-f5w6fw6q 6303 23 20 20 CD cord-006870-f5w6fw6q 6303 24 year year NN cord-006870-f5w6fw6q 6303 25 high high JJ cord-006870-f5w6fw6q 6303 26 within within IN cord-006870-f5w6fw6q 6303 27 the the DT cord-006870-f5w6fw6q 6303 28 US US NNP cord-006870-f5w6fw6q 6303 29 , , , cord-006870-f5w6fw6q 6303 30 this this DT cord-006870-f5w6fw6q 6303 31 phenomenon phenomenon NN cord-006870-f5w6fw6q 6303 32 may may MD cord-006870-f5w6fw6q 6303 33 become become VB cord-006870-f5w6fw6q 6303 34 more more RBR cord-006870-f5w6fw6q 6303 35 prominent prominent JJ cord-006870-f5w6fw6q 6303 36 . . . cord-006870-f5w6fw6q 6304 1 Heroin heroin NN cord-006870-f5w6fw6q 6304 2 inhalation inhalation NN cord-006870-f5w6fw6q 6304 3 leukoencephalopathy leukoencephalopathy NNP cord-006870-f5w6fw6q 6304 4 should should MD cord-006870-f5w6fw6q 6304 5 be be VB cord-006870-f5w6fw6q 6304 6 suspected suspect VBN cord-006870-f5w6fw6q 6304 7 in in IN cord-006870-f5w6fw6q 6304 8 all all DT cord-006870-f5w6fw6q 6304 9 patients patient NNS cord-006870-f5w6fw6q 6304 10 with with IN cord-006870-f5w6fw6q 6304 11 a a DT cord-006870-f5w6fw6q 6304 12 history history NN cord-006870-f5w6fw6q 6304 13 of of IN cord-006870-f5w6fw6q 6304 14 chasing chase VBG cord-006870-f5w6fw6q 6304 15 the the DT cord-006870-f5w6fw6q 6304 16 dragon dragon NN cord-006870-f5w6fw6q 6304 17 when when WRB cord-006870-f5w6fw6q 6304 18 they -PRON- PRP cord-006870-f5w6fw6q 6304 19 present present VBP cord-006870-f5w6fw6q 6304 20 with with IN cord-006870-f5w6fw6q 6304 21 neurological neurological JJ cord-006870-f5w6fw6q 6304 22 abnormalities abnormality NNS cord-006870-f5w6fw6q 6304 23 . . . cord-006870-f5w6fw6q 6305 1 The the DT cord-006870-f5w6fw6q 6305 2 use use NN cord-006870-f5w6fw6q 6305 3 of of IN cord-006870-f5w6fw6q 6305 4 intra intra JJ cord-006870-f5w6fw6q 6305 5 - - JJ cord-006870-f5w6fw6q 6305 6 venous venous JJ cord-006870-f5w6fw6q 6305 7 ( ( -LRB- cord-006870-f5w6fw6q 6305 8 IV IV NNP cord-006870-f5w6fw6q 6305 9 ) ) -RRB- cord-006870-f5w6fw6q 6305 10 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 6305 11 for for IN cord-006870-f5w6fw6q 6305 12 the the DT cord-006870-f5w6fw6q 6305 13 treatment treatment NN cord-006870-f5w6fw6q 6305 14 of of IN cord-006870-f5w6fw6q 6305 15 acute acute JJ cord-006870-f5w6fw6q 6305 16 ischemic ischemic JJ cord-006870-f5w6fw6q 6305 17 stroke stroke NN cord-006870-f5w6fw6q 6305 18 is be VBZ cord-006870-f5w6fw6q 6305 19 now now RB cord-006870-f5w6fw6q 6305 20 the the DT cord-006870-f5w6fw6q 6305 21 standard standard NN cord-006870-f5w6fw6q 6305 22 of of IN cord-006870-f5w6fw6q 6305 23 care care NN cord-006870-f5w6fw6q 6305 24 . . . cord-006870-f5w6fw6q 6306 1 This this DT cord-006870-f5w6fw6q 6306 2 is be VBZ cord-006870-f5w6fw6q 6306 3 typically typically RB cord-006870-f5w6fw6q 6306 4 followed follow VBN cord-006870-f5w6fw6q 6306 5 by by IN cord-006870-f5w6fw6q 6306 6 endovascular endovascular JJ cord-006870-f5w6fw6q 6306 7 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 6306 8 if if IN cord-006870-f5w6fw6q 6306 9 patient patient NN cord-006870-f5w6fw6q 6306 10 is be VBZ cord-006870-f5w6fw6q 6306 11 eligible eligible JJ cord-006870-f5w6fw6q 6306 12 does do VBZ cord-006870-f5w6fw6q 6306 13 not not RB cord-006870-f5w6fw6q 6306 14 improve improve VB cord-006870-f5w6fw6q 6306 15 . . . cord-006870-f5w6fw6q 6307 1 We -PRON- PRP cord-006870-f5w6fw6q 6307 2 present present VBP cord-006870-f5w6fw6q 6307 3 a a DT cord-006870-f5w6fw6q 6307 4 rare rare JJ cord-006870-f5w6fw6q 6307 5 acute acute JJ cord-006870-f5w6fw6q 6307 6 ischemic ischemic JJ cord-006870-f5w6fw6q 6307 7 posterior posterior JJ cord-006870-f5w6fw6q 6307 8 circulation circulation NN cord-006870-f5w6fw6q 6307 9 stroke stroke NN cord-006870-f5w6fw6q 6307 10 that that WDT cord-006870-f5w6fw6q 6307 11 had have VBD cord-006870-f5w6fw6q 6307 12 progression progression NN cord-006870-f5w6fw6q 6307 13 of of IN cord-006870-f5w6fw6q 6307 14 the the DT cord-006870-f5w6fw6q 6307 15 stroke stroke NN cord-006870-f5w6fw6q 6307 16 despite despite IN cord-006870-f5w6fw6q 6307 17 receiving receive VBG cord-006870-f5w6fw6q 6307 18 both both CC cord-006870-f5w6fw6q 6307 19 intra intra JJ cord-006870-f5w6fw6q 6307 20 - - JJ cord-006870-f5w6fw6q 6307 21 venous venous JJ cord-006870-f5w6fw6q 6307 22 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 6307 23 and and CC cord-006870-f5w6fw6q 6307 24 endovascular endovascular JJ cord-006870-f5w6fw6q 6307 25 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 6307 26 . . . cord-006870-f5w6fw6q 6308 1 Case Case NNP cord-006870-f5w6fw6q 6308 2 Report Report NNP cord-006870-f5w6fw6q 6308 3 : : : cord-006870-f5w6fw6q 6308 4 A a DT cord-006870-f5w6fw6q 6308 5 38 38 CD cord-006870-f5w6fw6q 6308 6 years year NNS cord-006870-f5w6fw6q 6308 7 old old JJ cord-006870-f5w6fw6q 6308 8 African african JJ cord-006870-f5w6fw6q 6308 9 - - HYPH cord-006870-f5w6fw6q 6308 10 American american JJ cord-006870-f5w6fw6q 6308 11 gentleman gentleman NN cord-006870-f5w6fw6q 6308 12 with with IN cord-006870-f5w6fw6q 6308 13 past past JJ cord-006870-f5w6fw6q 6308 14 history history NN cord-006870-f5w6fw6q 6308 15 of of IN cord-006870-f5w6fw6q 6308 16 obesity obesity NN cord-006870-f5w6fw6q 6308 17 , , , cord-006870-f5w6fw6q 6308 18 sleep sleep VB cord-006870-f5w6fw6q 6308 19 apnea apnea NN cord-006870-f5w6fw6q 6308 20 and and CC cord-006870-f5w6fw6q 6308 21 prostatic prostatic JJ cord-006870-f5w6fw6q 6308 22 hyperplasia hyperplasia NN cord-006870-f5w6fw6q 6308 23 , , , cord-006870-f5w6fw6q 6308 24 presented present VBN cord-006870-f5w6fw6q 6308 25 with with IN cord-006870-f5w6fw6q 6308 26 acute acute JJ cord-006870-f5w6fw6q 6308 27 onset onset NN cord-006870-f5w6fw6q 6308 28 left leave VBD cord-006870-f5w6fw6q 6308 29 hemiparesis hemiparesis NN cord-006870-f5w6fw6q 6308 30 , , , cord-006870-f5w6fw6q 6308 31 with with IN cord-006870-f5w6fw6q 6308 32 limb limb NN cord-006870-f5w6fw6q 6308 33 ataxia ataxia NN cord-006870-f5w6fw6q 6308 34 , , , cord-006870-f5w6fw6q 6308 35 who who WP cord-006870-f5w6fw6q 6308 36 then then RB cord-006870-f5w6fw6q 6308 37 progressed progress VBD cord-006870-f5w6fw6q 6308 38 to to IN cord-006870-f5w6fw6q 6308 39 altered alter VBN cord-006870-f5w6fw6q 6308 40 sensorium sensorium NN cord-006870-f5w6fw6q 6308 41 in in IN cord-006870-f5w6fw6q 6308 42 the the DT cord-006870-f5w6fw6q 6308 43 Emergency Emergency NNP cord-006870-f5w6fw6q 6308 44 Room Room NNP cord-006870-f5w6fw6q 6308 45 needing need VBG cord-006870-f5w6fw6q 6308 46 endotracheal endotracheal JJ cord-006870-f5w6fw6q 6308 47 intubation intubation NN cord-006870-f5w6fw6q 6308 48 . . . cord-006870-f5w6fw6q 6309 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6309 2 initial initial JJ cord-006870-f5w6fw6q 6309 3 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6309 4 was be VBD cord-006870-f5w6fw6q 6309 5 10 10 CD cord-006870-f5w6fw6q 6309 6 . . . cord-006870-f5w6fw6q 6310 1 He -PRON- PRP cord-006870-f5w6fw6q 6310 2 was be VBD cord-006870-f5w6fw6q 6310 3 given give VBN cord-006870-f5w6fw6q 6310 4 IV IV NNP cord-006870-f5w6fw6q 6310 5 thrombolysis thrombolysis NN cord-006870-f5w6fw6q 6310 6 , , , cord-006870-f5w6fw6q 6310 7 with with IN cord-006870-f5w6fw6q 6310 8 subsequent subsequent JJ cord-006870-f5w6fw6q 6310 9 vascular vascular JJ cord-006870-f5w6fw6q 6310 10 imaging imaging NN cord-006870-f5w6fw6q 6310 11 that that WDT cord-006870-f5w6fw6q 6310 12 showed show VBD cord-006870-f5w6fw6q 6310 13 a a DT cord-006870-f5w6fw6q 6310 14 top top NN cord-006870-f5w6fw6q 6310 15 of of IN cord-006870-f5w6fw6q 6310 16 the the DT cord-006870-f5w6fw6q 6310 17 basilar basilar JJ cord-006870-f5w6fw6q 6310 18 clot clot NN cord-006870-f5w6fw6q 6310 19 , , , cord-006870-f5w6fw6q 6310 20 that that WDT cord-006870-f5w6fw6q 6310 21 was be VBD cord-006870-f5w6fw6q 6310 22 removed remove VBN cord-006870-f5w6fw6q 6310 23 via via IN cord-006870-f5w6fw6q 6310 24 endovascular endovascular JJ cord-006870-f5w6fw6q 6310 25 intervention intervention NN cord-006870-f5w6fw6q 6310 26 . . . cord-006870-f5w6fw6q 6311 1 A a DT cord-006870-f5w6fw6q 6311 2 sister sister NN cord-006870-f5w6fw6q 6311 3 and and CC cord-006870-f5w6fw6q 6311 4 one one CD cord-006870-f5w6fw6q 6311 5 of of IN cord-006870-f5w6fw6q 6311 6 the the DT cord-006870-f5w6fw6q 6311 7 aunts aunt NNS cord-006870-f5w6fw6q 6311 8 reported report VBD cord-006870-f5w6fw6q 6311 9 a a DT cord-006870-f5w6fw6q 6311 10 history history NN cord-006870-f5w6fw6q 6311 11 of of IN cord-006870-f5w6fw6q 6311 12 ' ' `` cord-006870-f5w6fw6q 6311 13 clots clot NNS cord-006870-f5w6fw6q 6311 14 ' ' '' cord-006870-f5w6fw6q 6311 15 when when WRB cord-006870-f5w6fw6q 6311 16 asked ask VBN cord-006870-f5w6fw6q 6311 17 about about IN cord-006870-f5w6fw6q 6311 18 family family NN cord-006870-f5w6fw6q 6311 19 history history NN cord-006870-f5w6fw6q 6311 20 . . . cord-006870-f5w6fw6q 6312 1 Despite despite IN cord-006870-f5w6fw6q 6312 2 initial initial JJ cord-006870-f5w6fw6q 6312 3 improvement improvement NN cord-006870-f5w6fw6q 6312 4 , , , cord-006870-f5w6fw6q 6312 5 the the DT cord-006870-f5w6fw6q 6312 6 patient patient NN cord-006870-f5w6fw6q 6312 7 deteriorated deteriorate VBD cord-006870-f5w6fw6q 6312 8 clinically clinically RB cord-006870-f5w6fw6q 6312 9 after after IN cord-006870-f5w6fw6q 6312 10 about about RB cord-006870-f5w6fw6q 6312 11 14 14 CD cord-006870-f5w6fw6q 6312 12 hours hour NNS cord-006870-f5w6fw6q 6312 13 from from IN cord-006870-f5w6fw6q 6312 14 symptom symptom NN cord-006870-f5w6fw6q 6312 15 onset onset NN cord-006870-f5w6fw6q 6312 16 , , , cord-006870-f5w6fw6q 6312 17 and and CC cord-006870-f5w6fw6q 6312 18 was be VBD cord-006870-f5w6fw6q 6312 19 found find VBN cord-006870-f5w6fw6q 6312 20 to to TO cord-006870-f5w6fw6q 6312 21 have have VB cord-006870-f5w6fw6q 6312 22 extension extension NN cord-006870-f5w6fw6q 6312 23 of of IN cord-006870-f5w6fw6q 6312 24 stroke stroke NN cord-006870-f5w6fw6q 6312 25 into into IN cord-006870-f5w6fw6q 6312 26 the the DT cord-006870-f5w6fw6q 6312 27 brainstem brainstem NN cord-006870-f5w6fw6q 6312 28 , , , cord-006870-f5w6fw6q 6312 29 with with IN cord-006870-f5w6fw6q 6312 30 simultaneous simultaneous JJ cord-006870-f5w6fw6q 6312 31 acute acute JJ cord-006870-f5w6fw6q 6312 32 loss loss NN cord-006870-f5w6fw6q 6312 33 of of IN cord-006870-f5w6fw6q 6312 34 brainstem brainstem NN cord-006870-f5w6fw6q 6312 35 reflexes reflex NNS cord-006870-f5w6fw6q 6312 36 . . . cord-006870-f5w6fw6q 6313 1 The the DT cord-006870-f5w6fw6q 6313 2 patient patient NN cord-006870-f5w6fw6q 6313 3 was be VBD cord-006870-f5w6fw6q 6313 4 started start VBN cord-006870-f5w6fw6q 6313 5 on on IN cord-006870-f5w6fw6q 6313 6 palliative palliative JJ cord-006870-f5w6fw6q 6313 7 withdrawal withdrawal NN cord-006870-f5w6fw6q 6313 8 of of IN cord-006870-f5w6fw6q 6313 9 care care NN cord-006870-f5w6fw6q 6313 10 by by IN cord-006870-f5w6fw6q 6313 11 the the DT cord-006870-f5w6fw6q 6313 12 family family NN cord-006870-f5w6fw6q 6313 13 about about RB cord-006870-f5w6fw6q 6313 14 2 2 CD cord-006870-f5w6fw6q 6313 15 days day NNS cord-006870-f5w6fw6q 6313 16 from from IN cord-006870-f5w6fw6q 6313 17 the the DT cord-006870-f5w6fw6q 6313 18 initial initial JJ cord-006870-f5w6fw6q 6313 19 onset onset NN cord-006870-f5w6fw6q 6313 20 of of IN cord-006870-f5w6fw6q 6313 21 symptoms symptom NNS cord-006870-f5w6fw6q 6313 22 . . . cord-006870-f5w6fw6q 6314 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6314 2 thrombophilia thrombophilia NN cord-006870-f5w6fw6q 6314 3 work work NN cord-006870-f5w6fw6q 6314 4 - - HYPH cord-006870-f5w6fw6q 6314 5 up up NN cord-006870-f5w6fw6q 6314 6 revealed reveal VBD cord-006870-f5w6fw6q 6314 7 later later RB cord-006870-f5w6fw6q 6314 8 that that IN cord-006870-f5w6fw6q 6314 9 he -PRON- PRP cord-006870-f5w6fw6q 6314 10 was be VBD cord-006870-f5w6fw6q 6314 11 homozygous homozygous JJ cord-006870-f5w6fw6q 6314 12 for for IN cord-006870-f5w6fw6q 6314 13 Methylenetetrahydrofolate Methylenetetrahydrofolate NNP cord-006870-f5w6fw6q 6314 14 reductase reductase NN cord-006870-f5w6fw6q 6314 15 ( ( -LRB- cord-006870-f5w6fw6q 6314 16 MTHFR MTHFR NNP cord-006870-f5w6fw6q 6314 17 ) ) -RRB- cord-006870-f5w6fw6q 6315 1 gene gene NNP cord-006870-f5w6fw6q 6315 2 mutation mutation NN cord-006870-f5w6fw6q 6315 3 , , , cord-006870-f5w6fw6q 6316 1 677C 677c CD cord-006870-f5w6fw6q 6317 1 > > XX cord-006870-f5w6fw6q 6318 1 T. t. NN cord-006870-f5w6fw6q 6319 1 This this DT cord-006870-f5w6fw6q 6319 2 case case NN cord-006870-f5w6fw6q 6319 3 with with IN cord-006870-f5w6fw6q 6319 4 a a DT cord-006870-f5w6fw6q 6319 5 poor poor JJ cord-006870-f5w6fw6q 6319 6 outcome outcome NN cord-006870-f5w6fw6q 6319 7 due due IN cord-006870-f5w6fw6q 6319 8 to to IN cord-006870-f5w6fw6q 6319 9 extension extension NN cord-006870-f5w6fw6q 6319 10 of of IN cord-006870-f5w6fw6q 6319 11 the the DT cord-006870-f5w6fw6q 6319 12 ischemic ischemic JJ cord-006870-f5w6fw6q 6319 13 stroke stroke NN cord-006870-f5w6fw6q 6319 14 despite despite IN cord-006870-f5w6fw6q 6319 15 receiving receive VBG cord-006870-f5w6fw6q 6319 16 the the DT cord-006870-f5w6fw6q 6319 17 standard standard NN cord-006870-f5w6fw6q 6319 18 of of IN cord-006870-f5w6fw6q 6319 19 care care NN cord-006870-f5w6fw6q 6319 20 therapy therapy NN cord-006870-f5w6fw6q 6319 21 , , , cord-006870-f5w6fw6q 6319 22 highlights highlight VBZ cord-006870-f5w6fw6q 6319 23 the the DT cord-006870-f5w6fw6q 6319 24 need need NN cord-006870-f5w6fw6q 6319 25 for for IN cord-006870-f5w6fw6q 6319 26 considering consider VBG cord-006870-f5w6fw6q 6319 27 the the DT cord-006870-f5w6fw6q 6319 28 use use NN cord-006870-f5w6fw6q 6319 29 of of IN cord-006870-f5w6fw6q 6319 30 anticoagulation anticoagulation NN cord-006870-f5w6fw6q 6319 31 within within IN cord-006870-f5w6fw6q 6319 32 24 24 CD cord-006870-f5w6fw6q 6319 33 hours hour NNS cord-006870-f5w6fw6q 6319 34 postthrombolysis postthrombolysis NN cord-006870-f5w6fw6q 6319 35 and and CC cord-006870-f5w6fw6q 6319 36 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 6319 37 in in IN cord-006870-f5w6fw6q 6319 38 cases case NNS cord-006870-f5w6fw6q 6319 39 with with IN cord-006870-f5w6fw6q 6319 40 underlying underlie VBG cord-006870-f5w6fw6q 6319 41 thrombophilia thrombophilia NNP cord-006870-f5w6fw6q 6319 42 . . . cord-006870-f5w6fw6q 6320 1 The the DT cord-006870-f5w6fw6q 6320 2 current current JJ cord-006870-f5w6fw6q 6320 3 guidelines guideline NNS cord-006870-f5w6fw6q 6320 4 do do VBP cord-006870-f5w6fw6q 6320 5 not not RB cord-006870-f5w6fw6q 6320 6 support support VB cord-006870-f5w6fw6q 6320 7 this this DT cord-006870-f5w6fw6q 6320 8 aggressive aggressive JJ cord-006870-f5w6fw6q 6320 9 approach approach NN cord-006870-f5w6fw6q 6320 10 . . . cord-006870-f5w6fw6q 6321 1 There there EX cord-006870-f5w6fw6q 6321 2 is be VBZ cord-006870-f5w6fw6q 6321 3 a a DT cord-006870-f5w6fw6q 6321 4 dire dire JJ cord-006870-f5w6fw6q 6321 5 need need NN cord-006870-f5w6fw6q 6321 6 for for IN cord-006870-f5w6fw6q 6321 7 randomized randomized JJ cord-006870-f5w6fw6q 6321 8 controlled control VBN cord-006870-f5w6fw6q 6321 9 trial trial NN cord-006870-f5w6fw6q 6321 10 about about IN cord-006870-f5w6fw6q 6321 11 such such JJ cord-006870-f5w6fw6q 6321 12 cases case NNS cord-006870-f5w6fw6q 6321 13 to to TO cord-006870-f5w6fw6q 6321 14 provide provide VB cord-006870-f5w6fw6q 6321 15 evidence evidence NN cord-006870-f5w6fw6q 6321 16 based base VBN cord-006870-f5w6fw6q 6321 17 care care NN cord-006870-f5w6fw6q 6321 18 to to TO cord-006870-f5w6fw6q 6321 19 avoid avoid VB cord-006870-f5w6fw6q 6321 20 a a DT cord-006870-f5w6fw6q 6321 21 repetition repetition NN cord-006870-f5w6fw6q 6321 22 of of IN cord-006870-f5w6fw6q 6321 23 a a DT cord-006870-f5w6fw6q 6321 24 similar similar JJ cord-006870-f5w6fw6q 6321 25 poor poor JJ cord-006870-f5w6fw6q 6321 26 outcome outcome NN cord-006870-f5w6fw6q 6321 27 . . . cord-006870-f5w6fw6q 6322 1 Barbiturate barbiturate NN cord-006870-f5w6fw6q 6322 2 therapy therapy NN cord-006870-f5w6fw6q 6322 3 has have VBZ cord-006870-f5w6fw6q 6322 4 shown show VBN cord-006870-f5w6fw6q 6322 5 benefit benefit NN cord-006870-f5w6fw6q 6322 6 in in IN cord-006870-f5w6fw6q 6322 7 reducing reduce VBG cord-006870-f5w6fw6q 6322 8 intracranial intracranial JJ cord-006870-f5w6fw6q 6322 9 pressure pressure NN cord-006870-f5w6fw6q 6322 10 ( ( -LRB- cord-006870-f5w6fw6q 6322 11 ICP ICP NNP cord-006870-f5w6fw6q 6322 12 ) ) -RRB- cord-006870-f5w6fw6q 6322 13 in in IN cord-006870-f5w6fw6q 6322 14 patients patient NNS cord-006870-f5w6fw6q 6322 15 who who WP cord-006870-f5w6fw6q 6322 16 are be VBP cord-006870-f5w6fw6q 6322 17 refractory refractory JJ cord-006870-f5w6fw6q 6322 18 to to IN cord-006870-f5w6fw6q 6322 19 other other JJ cord-006870-f5w6fw6q 6322 20 treatment treatment NN cord-006870-f5w6fw6q 6322 21 modalities modality NNS cord-006870-f5w6fw6q 6322 22 . . . cord-006870-f5w6fw6q 6323 1 However however RB cord-006870-f5w6fw6q 6323 2 , , , cord-006870-f5w6fw6q 6323 3 severe severe JJ cord-006870-f5w6fw6q 6323 4 adverse adverse JJ cord-006870-f5w6fw6q 6323 5 drug drug NN cord-006870-f5w6fw6q 6323 6 effects effect NNS cord-006870-f5w6fw6q 6323 7 can can MD cord-006870-f5w6fw6q 6323 8 accompany accompany VB cord-006870-f5w6fw6q 6323 9 barbiturate barbiturate NN cord-006870-f5w6fw6q 6323 10 use use NN cord-006870-f5w6fw6q 6323 11 when when WRB cord-006870-f5w6fw6q 6323 12 used use VBN cord-006870-f5w6fw6q 6323 13 at at IN cord-006870-f5w6fw6q 6323 14 the the DT cord-006870-f5w6fw6q 6323 15 high high JJ cord-006870-f5w6fw6q 6323 16 doses dose NNS cord-006870-f5w6fw6q 6323 17 required require VBN cord-006870-f5w6fw6q 6323 18 for for IN cord-006870-f5w6fw6q 6323 19 ICP ICP NNP cord-006870-f5w6fw6q 6323 20 management management NN cord-006870-f5w6fw6q 6323 21 , , , cord-006870-f5w6fw6q 6323 22 such such JJ cord-006870-f5w6fw6q 6323 23 as as IN cord-006870-f5w6fw6q 6323 24 hypotension hypotension NN cord-006870-f5w6fw6q 6323 25 , , , cord-006870-f5w6fw6q 6323 26 hepatic hepatic JJ cord-006870-f5w6fw6q 6323 27 / / SYM cord-006870-f5w6fw6q 6323 28 renal renal JJ cord-006870-f5w6fw6q 6323 29 dysfunction dysfunction NN cord-006870-f5w6fw6q 6323 30 , , , cord-006870-f5w6fw6q 6323 31 and and CC cord-006870-f5w6fw6q 6323 32 infection infection NN cord-006870-f5w6fw6q 6323 33 , , , cord-006870-f5w6fw6q 6323 34 among among IN cord-006870-f5w6fw6q 6323 35 other other JJ cord-006870-f5w6fw6q 6323 36 deleterious deleterious JJ cord-006870-f5w6fw6q 6323 37 consequences consequence NNS cord-006870-f5w6fw6q 6323 38 . . . cord-006870-f5w6fw6q 6324 1 Dyskalemia Dyskalemia NNP cord-006870-f5w6fw6q 6324 2 has have VBZ cord-006870-f5w6fw6q 6324 3 been be VBN cord-006870-f5w6fw6q 6324 4 reported report VBN cord-006870-f5w6fw6q 6324 5 infrequently infrequently RB cord-006870-f5w6fw6q 6324 6 in in IN cord-006870-f5w6fw6q 6324 7 the the DT cord-006870-f5w6fw6q 6324 8 literature literature NN cord-006870-f5w6fw6q 6324 9 with with IN cord-006870-f5w6fw6q 6324 10 most most JJS cord-006870-f5w6fw6q 6324 11 of of IN cord-006870-f5w6fw6q 6324 12 the the DT cord-006870-f5w6fw6q 6324 13 cases case NNS cord-006870-f5w6fw6q 6324 14 involving involve VBG cord-006870-f5w6fw6q 6324 15 patients patient NNS cord-006870-f5w6fw6q 6324 16 on on IN cord-006870-f5w6fw6q 6324 17 thiopental thiopental NN cord-006870-f5w6fw6q 6324 18 . . . cord-006870-f5w6fw6q 6325 1 There there EX cord-006870-f5w6fw6q 6325 2 remains remain VBZ cord-006870-f5w6fw6q 6325 3 little little JJ cord-006870-f5w6fw6q 6325 4 guidance guidance NN cord-006870-f5w6fw6q 6325 5 for for IN cord-006870-f5w6fw6q 6325 6 management management NN cord-006870-f5w6fw6q 6325 7 of of IN cord-006870-f5w6fw6q 6325 8 this this DT cord-006870-f5w6fw6q 6325 9 adverse adverse JJ cord-006870-f5w6fw6q 6325 10 effect effect NN cord-006870-f5w6fw6q 6325 11 . . . cord-006870-f5w6fw6q 6326 1 We -PRON- PRP cord-006870-f5w6fw6q 6326 2 present present VBP cord-006870-f5w6fw6q 6326 3 a a DT cord-006870-f5w6fw6q 6326 4 case case NN cord-006870-f5w6fw6q 6326 5 of of IN cord-006870-f5w6fw6q 6326 6 severe severe JJ cord-006870-f5w6fw6q 6326 7 dyskalemia dyskalemia NN cord-006870-f5w6fw6q 6326 8 induced induce VBN cord-006870-f5w6fw6q 6326 9 by by IN cord-006870-f5w6fw6q 6326 10 high high JJ cord-006870-f5w6fw6q 6326 11 - - HYPH cord-006870-f5w6fw6q 6326 12 dose dose NN cord-006870-f5w6fw6q 6326 13 pentobarbital pentobarbital JJ cord-006870-f5w6fw6q 6326 14 therapy therapy NN cord-006870-f5w6fw6q 6326 15 and and CC cord-006870-f5w6fw6q 6326 16 experience experience NN cord-006870-f5w6fw6q 6326 17 with with IN cord-006870-f5w6fw6q 6326 18 management management NN cord-006870-f5w6fw6q 6326 19 of of IN cord-006870-f5w6fw6q 6326 20 this this DT cord-006870-f5w6fw6q 6326 21 rare rare JJ cord-006870-f5w6fw6q 6326 22 but but CC cord-006870-f5w6fw6q 6326 23 life life NN cord-006870-f5w6fw6q 6326 24 threatening threaten VBG cord-006870-f5w6fw6q 6326 25 effect effect NN cord-006870-f5w6fw6q 6326 26 . . . cord-006870-f5w6fw6q 6327 1 The the DT cord-006870-f5w6fw6q 6327 2 patient patient NN cord-006870-f5w6fw6q 6327 3 was be VBD cord-006870-f5w6fw6q 6327 4 a a DT cord-006870-f5w6fw6q 6327 5 26-year 26-year JJ cord-006870-f5w6fw6q 6327 6 - - HYPH cord-006870-f5w6fw6q 6327 7 old old JJ cord-006870-f5w6fw6q 6327 8 male male NN cord-006870-f5w6fw6q 6327 9 with with IN cord-006870-f5w6fw6q 6327 10 traumatic traumatic JJ cord-006870-f5w6fw6q 6327 11 brain brain NN cord-006870-f5w6fw6q 6327 12 injury injury NN cord-006870-f5w6fw6q 6327 13 and and CC cord-006870-f5w6fw6q 6327 14 subdural subdural JJ cord-006870-f5w6fw6q 6327 15 hematomas hematoma NNS cord-006870-f5w6fw6q 6327 16 complicated complicate VBN cord-006870-f5w6fw6q 6327 17 by by IN cord-006870-f5w6fw6q 6327 18 refractory refractory JJ cord-006870-f5w6fw6q 6327 19 ICP ICP NNP cord-006870-f5w6fw6q 6327 20 elevations elevation NNS cord-006870-f5w6fw6q 6327 21 . . . cord-006870-f5w6fw6q 6328 1 After after IN cord-006870-f5w6fw6q 6328 2 hyperosmolar hyperosmolar NNP cord-006870-f5w6fw6q 6328 3 therapy therapy NN cord-006870-f5w6fw6q 6328 4 , , , cord-006870-f5w6fw6q 6328 5 sedation sedation NN cord-006870-f5w6fw6q 6328 6 , , , cord-006870-f5w6fw6q 6328 7 and and CC cord-006870-f5w6fw6q 6328 8 CSF CSF NNP cord-006870-f5w6fw6q 6328 9 drainage drainage NN cord-006870-f5w6fw6q 6328 10 failed fail VBD cord-006870-f5w6fw6q 6328 11 to to TO cord-006870-f5w6fw6q 6328 12 control control VB cord-006870-f5w6fw6q 6328 13 ICP ICP NNP cord-006870-f5w6fw6q 6328 14 , , , cord-006870-f5w6fw6q 6328 15 and and CC cord-006870-f5w6fw6q 6328 16 he -PRON- PRP cord-006870-f5w6fw6q 6328 17 was be VBD cord-006870-f5w6fw6q 6328 18 deemed deem VBN cord-006870-f5w6fw6q 6328 19 to to TO cord-006870-f5w6fw6q 6328 20 not not RB cord-006870-f5w6fw6q 6328 21 be be VB cord-006870-f5w6fw6q 6328 22 a a DT cord-006870-f5w6fw6q 6328 23 candidate candidate NN cord-006870-f5w6fw6q 6328 24 for for IN cord-006870-f5w6fw6q 6328 25 surgical surgical JJ cord-006870-f5w6fw6q 6328 26 decompression decompression NN cord-006870-f5w6fw6q 6328 27 , , , cord-006870-f5w6fw6q 6328 28 high high JJ cord-006870-f5w6fw6q 6328 29 - - HYPH cord-006870-f5w6fw6q 6328 30 dose dose NN cord-006870-f5w6fw6q 6328 31 pentobarbital pentobarbital NN cord-006870-f5w6fw6q 6328 32 was be VBD cord-006870-f5w6fw6q 6328 33 started start VBN cord-006870-f5w6fw6q 6328 34 . . . cord-006870-f5w6fw6q 6329 1 After after IN cord-006870-f5w6fw6q 6329 2 initiation initiation NN cord-006870-f5w6fw6q 6329 3 of of IN cord-006870-f5w6fw6q 6329 4 pentobarbital pentobarbital NN cord-006870-f5w6fw6q 6329 5 , , , cord-006870-f5w6fw6q 6329 6 his -PRON- PRP$ cord-006870-f5w6fw6q 6329 7 initial initial JJ cord-006870-f5w6fw6q 6329 8 potassium potassium NN cord-006870-f5w6fw6q 6329 9 of of IN cord-006870-f5w6fw6q 6329 10 4.0 4.0 CD cord-006870-f5w6fw6q 6329 11 mmol mmol JJ cord-006870-f5w6fw6q 6329 12 / / SYM cord-006870-f5w6fw6q 6329 13 L L NNP cord-006870-f5w6fw6q 6329 14 decreased decrease VBD cord-006870-f5w6fw6q 6329 15 to to IN cord-006870-f5w6fw6q 6329 16 a a DT cord-006870-f5w6fw6q 6329 17 nadir nadir NN cord-006870-f5w6fw6q 6329 18 of of IN cord-006870-f5w6fw6q 6329 19 1.9 1.9 CD cord-006870-f5w6fw6q 6329 20 mmol mmol NNP cord-006870-f5w6fw6q 6329 21 / / SYM cord-006870-f5w6fw6q 6329 22 L l NN cord-006870-f5w6fw6q 6329 23 over over IN cord-006870-f5w6fw6q 6329 24 the the DT cord-006870-f5w6fw6q 6329 25 next next JJ cord-006870-f5w6fw6q 6329 26 24 24 CD cord-006870-f5w6fw6q 6329 27 hours hour NNS cord-006870-f5w6fw6q 6329 28 despite despite IN cord-006870-f5w6fw6q 6329 29 aggressive aggressive JJ cord-006870-f5w6fw6q 6329 30 repletion repletion NN cord-006870-f5w6fw6q 6329 31 with with IN cord-006870-f5w6fw6q 6329 32 a a DT cord-006870-f5w6fw6q 6329 33 total total NN cord-006870-f5w6fw6q 6329 34 of of IN cord-006870-f5w6fw6q 6329 35 600 600 CD cord-006870-f5w6fw6q 6329 36 mEq mEq NNS cord-006870-f5w6fw6q 6329 37 of of IN cord-006870-f5w6fw6q 6329 38 oral oral JJ cord-006870-f5w6fw6q 6329 39 and and CC cord-006870-f5w6fw6q 6329 40 intravenous intravenous JJ cord-006870-f5w6fw6q 6329 41 potassium potassium NN cord-006870-f5w6fw6q 6329 42 chloride chloride NN cord-006870-f5w6fw6q 6329 43 . . . cord-006870-f5w6fw6q 6330 1 Upon upon IN cord-006870-f5w6fw6q 6330 2 down down IN cord-006870-f5w6fw6q 6330 3 - - HYPH cord-006870-f5w6fw6q 6330 4 titration titration NN cord-006870-f5w6fw6q 6330 5 and and CC cord-006870-f5w6fw6q 6330 6 discontinuation discontinuation NN cord-006870-f5w6fw6q 6330 7 of of IN cord-006870-f5w6fw6q 6330 8 pentobarbital pentobarbital NN cord-006870-f5w6fw6q 6330 9 , , , cord-006870-f5w6fw6q 6330 10 the the DT cord-006870-f5w6fw6q 6330 11 serum serum NN cord-006870-f5w6fw6q 6330 12 potassium potassium NN cord-006870-f5w6fw6q 6330 13 rapidly rapidly RB cord-006870-f5w6fw6q 6330 14 rebounded rebound VBD cord-006870-f5w6fw6q 6330 15 to to IN cord-006870-f5w6fw6q 6330 16 8.3 8.3 CD cord-006870-f5w6fw6q 6330 17 mmol mmol JJ cord-006870-f5w6fw6q 6330 18 / / SYM cord-006870-f5w6fw6q 6330 19 L L NNP cord-006870-f5w6fw6q 6330 20 with with IN cord-006870-f5w6fw6q 6330 21 ST ST NNP cord-006870-f5w6fw6q 6330 22 - - HYPH cord-006870-f5w6fw6q 6330 23 segment segment NN cord-006870-f5w6fw6q 6330 24 elevations elevation NNS cord-006870-f5w6fw6q 6330 25 on on IN cord-006870-f5w6fw6q 6330 26 EKG EKG NNP cord-006870-f5w6fw6q 6330 27 . . . cord-006870-f5w6fw6q 6331 1 Pentobarbital Pentobarbital NNP cord-006870-f5w6fw6q 6331 2 was be VBD cord-006870-f5w6fw6q 6331 3 restarted restart VBN cord-006870-f5w6fw6q 6331 4 in in IN cord-006870-f5w6fw6q 6331 5 an an DT cord-006870-f5w6fw6q 6331 6 attempt attempt NN cord-006870-f5w6fw6q 6331 7 to to TO cord-006870-f5w6fw6q 6331 8 stabilize stabilize VB cord-006870-f5w6fw6q 6331 9 escalating escalate VBG cord-006870-f5w6fw6q 6331 10 ICPs icp NNS cord-006870-f5w6fw6q 6331 11 and and CC cord-006870-f5w6fw6q 6331 12 elevated elevated JJ cord-006870-f5w6fw6q 6331 13 serum serum NN cord-006870-f5w6fw6q 6331 14 potassium potassium NN cord-006870-f5w6fw6q 6331 15 . . . cord-006870-f5w6fw6q 6332 1 Subsequently subsequently RB cord-006870-f5w6fw6q 6332 2 a a DT cord-006870-f5w6fw6q 6332 3 slow slow JJ cord-006870-f5w6fw6q 6332 4 taper taper NN cord-006870-f5w6fw6q 6332 5 was be VBD cord-006870-f5w6fw6q 6332 6 utilized utilize VBN cord-006870-f5w6fw6q 6332 7 to to TO cord-006870-f5w6fw6q 6332 8 mitigate mitigate VB cord-006870-f5w6fw6q 6332 9 dyskalemia dyskalemia NN cord-006870-f5w6fw6q 6332 10 during during IN cord-006870-f5w6fw6q 6332 11 barbiturate barbiturate NN cord-006870-f5w6fw6q 6332 12 discontinuation discontinuation NN cord-006870-f5w6fw6q 6332 13 . . . cord-006870-f5w6fw6q 6333 1 Dyskalemia Dyskalemia NNP cord-006870-f5w6fw6q 6333 2 associated associate VBN cord-006870-f5w6fw6q 6333 3 with with IN cord-006870-f5w6fw6q 6333 4 high high JJ cord-006870-f5w6fw6q 6333 5 - - HYPH cord-006870-f5w6fw6q 6333 6 dose dose NN cord-006870-f5w6fw6q 6333 7 barbiturate barbiturate NN cord-006870-f5w6fw6q 6333 8 therapy therapy NN cord-006870-f5w6fw6q 6333 9 presents present VBZ cord-006870-f5w6fw6q 6333 10 a a DT cord-006870-f5w6fw6q 6333 11 significant significant JJ cord-006870-f5w6fw6q 6333 12 dilemma dilemma NN cord-006870-f5w6fw6q 6333 13 to to IN cord-006870-f5w6fw6q 6333 14 practitioners practitioner NNS cord-006870-f5w6fw6q 6333 15 as as IN cord-006870-f5w6fw6q 6333 16 both both DT cord-006870-f5w6fw6q 6333 17 severe severe JJ cord-006870-f5w6fw6q 6333 18 hypo hypo NN cord-006870-f5w6fw6q 6333 19 - - : cord-006870-f5w6fw6q 6333 20 and and CC cord-006870-f5w6fw6q 6333 21 hyperkalemia hyperkalemia NN cord-006870-f5w6fw6q 6333 22 can can MD cord-006870-f5w6fw6q 6333 23 be be VB cord-006870-f5w6fw6q 6333 24 life life NN cord-006870-f5w6fw6q 6333 25 threatening threaten VBG cord-006870-f5w6fw6q 6333 26 . . . cord-006870-f5w6fw6q 6334 1 Published publish VBN cord-006870-f5w6fw6q 6334 2 literature literature NN cord-006870-f5w6fw6q 6334 3 provides provide VBZ cord-006870-f5w6fw6q 6334 4 little little JJ cord-006870-f5w6fw6q 6334 5 guidance guidance NN cord-006870-f5w6fw6q 6334 6 on on IN cord-006870-f5w6fw6q 6334 7 how how WRB cord-006870-f5w6fw6q 6334 8 to to TO cord-006870-f5w6fw6q 6334 9 safely safely RB cord-006870-f5w6fw6q 6334 10 manage manage VB cord-006870-f5w6fw6q 6334 11 patients patient NNS cord-006870-f5w6fw6q 6334 12 who who WP cord-006870-f5w6fw6q 6334 13 experience experience VBP cord-006870-f5w6fw6q 6334 14 this this DT cord-006870-f5w6fw6q 6334 15 adverse adverse JJ cord-006870-f5w6fw6q 6334 16 effect effect NN cord-006870-f5w6fw6q 6334 17 . . . cord-006870-f5w6fw6q 6335 1 Patients patient NNS cord-006870-f5w6fw6q 6335 2 receiving receive VBG cord-006870-f5w6fw6q 6335 3 barbiturate barbiturate NN cord-006870-f5w6fw6q 6335 4 therapy therapy NN cord-006870-f5w6fw6q 6335 5 should should MD cord-006870-f5w6fw6q 6335 6 have have VB cord-006870-f5w6fw6q 6335 7 frequent frequent JJ cord-006870-f5w6fw6q 6335 8 potassium potassium NN cord-006870-f5w6fw6q 6335 9 monitoring monitoring NN cord-006870-f5w6fw6q 6335 10 especially especially RB cord-006870-f5w6fw6q 6335 11 in in IN cord-006870-f5w6fw6q 6335 12 the the DT cord-006870-f5w6fw6q 6335 13 initiation initiation NN cord-006870-f5w6fw6q 6335 14 and and CC cord-006870-f5w6fw6q 6335 15 discontinuation discontinuation NN cord-006870-f5w6fw6q 6335 16 phases phase NNS cord-006870-f5w6fw6q 6335 17 . . . cord-006870-f5w6fw6q 6336 1 Potassium potassium NN cord-006870-f5w6fw6q 6336 2 repletion repletion NN cord-006870-f5w6fw6q 6336 3 should should MD cord-006870-f5w6fw6q 6336 4 be be VB cord-006870-f5w6fw6q 6336 5 approached approach VBN cord-006870-f5w6fw6q 6336 6 with with IN cord-006870-f5w6fw6q 6336 7 caution caution NN cord-006870-f5w6fw6q 6336 8 , , , cord-006870-f5w6fw6q 6336 9 especially especially RB cord-006870-f5w6fw6q 6336 10 preceding precede VBG cord-006870-f5w6fw6q 6336 11 discontinuation discontinuation NN cord-006870-f5w6fw6q 6336 12 of of IN cord-006870-f5w6fw6q 6336 13 barbiturate barbiturate NN cord-006870-f5w6fw6q 6336 14 therapy therapy NN cord-006870-f5w6fw6q 6336 15 . . . cord-006870-f5w6fw6q 6337 1 Diffuse diffuse JJ cord-006870-f5w6fw6q 6337 2 astrocytoma astrocytoma NN cord-006870-f5w6fw6q 6337 3 ( ( -LRB- cord-006870-f5w6fw6q 6337 4 formerly formerly RB cord-006870-f5w6fw6q 6337 5 known know VBN cord-006870-f5w6fw6q 6337 6 as as IN cord-006870-f5w6fw6q 6337 7 ' ' `` cord-006870-f5w6fw6q 6337 8 Gliomatosis gliomatosis NN cord-006870-f5w6fw6q 6337 9 cerebri cerebri NN cord-006870-f5w6fw6q 6337 10 ' ' '' cord-006870-f5w6fw6q 6337 11 ) ) -RRB- cord-006870-f5w6fw6q 6337 12 may may MD cord-006870-f5w6fw6q 6337 13 present present VB cord-006870-f5w6fw6q 6337 14 with with IN cord-006870-f5w6fw6q 6337 15 seizures seizure NNS cord-006870-f5w6fw6q 6337 16 or or CC cord-006870-f5w6fw6q 6337 17 symptomatic symptomatic JJ cord-006870-f5w6fw6q 6337 18 raised raise VBN cord-006870-f5w6fw6q 6337 19 intra intra JJ cord-006870-f5w6fw6q 6337 20 - - JJ cord-006870-f5w6fw6q 6337 21 cranial cranial JJ cord-006870-f5w6fw6q 6337 22 pressure pressure NN cord-006870-f5w6fw6q 6337 23 . . . cord-006870-f5w6fw6q 6338 1 This this DT cord-006870-f5w6fw6q 6338 2 is be VBZ cord-006870-f5w6fw6q 6338 3 typically typically RB cord-006870-f5w6fw6q 6338 4 followed follow VBN cord-006870-f5w6fw6q 6338 5 by by IN cord-006870-f5w6fw6q 6338 6 a a DT cord-006870-f5w6fw6q 6338 7 few few JJ cord-006870-f5w6fw6q 6338 8 months month NNS cord-006870-f5w6fw6q 6338 9 of of IN cord-006870-f5w6fw6q 6338 10 relatively relatively RB cord-006870-f5w6fw6q 6338 11 stable stable JJ cord-006870-f5w6fw6q 6338 12 phase phase NN cord-006870-f5w6fw6q 6338 13 ( ( -LRB- cord-006870-f5w6fw6q 6338 14 with with IN cord-006870-f5w6fw6q 6338 15 treatment treatment NN cord-006870-f5w6fw6q 6338 16 ) ) -RRB- cord-006870-f5w6fw6q 6338 17 and and CC cord-006870-f5w6fw6q 6338 18 then then RB cord-006870-f5w6fw6q 6338 19 possible possible JJ cord-006870-f5w6fw6q 6338 20 subsequent subsequent JJ cord-006870-f5w6fw6q 6338 21 development development NN cord-006870-f5w6fw6q 6338 22 of of IN cord-006870-f5w6fw6q 6338 23 Glioblastoma Glioblastoma NNP cord-006870-f5w6fw6q 6338 24 multiforme multiforme NNP cord-006870-f5w6fw6q 6338 25 . . . cord-006870-f5w6fw6q 6339 1 We -PRON- PRP cord-006870-f5w6fw6q 6339 2 present present VBP cord-006870-f5w6fw6q 6339 3 a a DT cord-006870-f5w6fw6q 6339 4 rare rare JJ cord-006870-f5w6fw6q 6339 5 case case NN cord-006870-f5w6fw6q 6339 6 of of IN cord-006870-f5w6fw6q 6339 7 a a DT cord-006870-f5w6fw6q 6339 8 previously previously RB cord-006870-f5w6fw6q 6339 9 healthy healthy JJ cord-006870-f5w6fw6q 6339 10 Caucasian caucasian JJ cord-006870-f5w6fw6q 6339 11 lady lady NN cord-006870-f5w6fw6q 6339 12 who who WP cord-006870-f5w6fw6q 6339 13 had have VBD cord-006870-f5w6fw6q 6339 14 new new JJ cord-006870-f5w6fw6q 6339 15 onset onset NN cord-006870-f5w6fw6q 6339 16 seizures seizure NNS cord-006870-f5w6fw6q 6339 17 , , , cord-006870-f5w6fw6q 6339 18 that that WDT cord-006870-f5w6fw6q 6339 19 showed show VBD cord-006870-f5w6fw6q 6339 20 glioblastoma glioblastoma NN cord-006870-f5w6fw6q 6339 21 multiforme multiforme NN cord-006870-f5w6fw6q 6339 22 already already RB cord-006870-f5w6fw6q 6339 23 present present JJ cord-006870-f5w6fw6q 6339 24 on on IN cord-006870-f5w6fw6q 6339 25 a a DT cord-006870-f5w6fw6q 6339 26 background background NN cord-006870-f5w6fw6q 6339 27 of of IN cord-006870-f5w6fw6q 6339 28 diffuse diffuse JJ cord-006870-f5w6fw6q 6339 29 astrocytoma astrocytoma NN cord-006870-f5w6fw6q 6339 30 . . . cord-006870-f5w6fw6q 6340 1 Case case NN cord-006870-f5w6fw6q 6340 2 report report NN cord-006870-f5w6fw6q 6340 3 : : : cord-006870-f5w6fw6q 6340 4 A a DT cord-006870-f5w6fw6q 6340 5 65 65 CD cord-006870-f5w6fw6q 6340 6 years year NNS cord-006870-f5w6fw6q 6340 7 old old JJ cord-006870-f5w6fw6q 6340 8 Caucasian caucasian JJ cord-006870-f5w6fw6q 6340 9 lady lady NN cord-006870-f5w6fw6q 6340 10 with with IN cord-006870-f5w6fw6q 6340 11 no no DT cord-006870-f5w6fw6q 6340 12 significant significant JJ cord-006870-f5w6fw6q 6340 13 past past JJ cord-006870-f5w6fw6q 6340 14 medical medical JJ cord-006870-f5w6fw6q 6340 15 history history NN cord-006870-f5w6fw6q 6340 16 was be VBD cord-006870-f5w6fw6q 6340 17 admitted admit VBN cord-006870-f5w6fw6q 6340 18 with with IN cord-006870-f5w6fw6q 6340 19 new new JJ cord-006870-f5w6fw6q 6340 20 onset onset JJ cord-006870-f5w6fw6q 6340 21 focal focal JJ cord-006870-f5w6fw6q 6340 22 seizures seizure NNS cord-006870-f5w6fw6q 6340 23 with with IN cord-006870-f5w6fw6q 6340 24 secondary secondary JJ cord-006870-f5w6fw6q 6340 25 generalization generalization NN cord-006870-f5w6fw6q 6340 26 , , , cord-006870-f5w6fw6q 6340 27 needing need VBG cord-006870-f5w6fw6q 6340 28 intubation intubation NN cord-006870-f5w6fw6q 6340 29 and and CC cord-006870-f5w6fw6q 6340 30 Propofol propofol NN cord-006870-f5w6fw6q 6340 31 for for IN cord-006870-f5w6fw6q 6340 32 airway airway NN cord-006870-f5w6fw6q 6340 33 protection protection NN cord-006870-f5w6fw6q 6340 34 . . . cord-006870-f5w6fw6q 6341 1 Brain brain NN cord-006870-f5w6fw6q 6341 2 imaging imaging NN cord-006870-f5w6fw6q 6341 3 showed show VBD cord-006870-f5w6fw6q 6341 4 left leave VBN cord-006870-f5w6fw6q 6341 5 frontal frontal JJ cord-006870-f5w6fw6q 6341 6 ring ring NN cord-006870-f5w6fw6q 6341 7 - - HYPH cord-006870-f5w6fw6q 6341 8 enhancing enhance VBG cord-006870-f5w6fw6q 6341 9 mass mass NN cord-006870-f5w6fw6q 6341 10 , , , cord-006870-f5w6fw6q 6341 11 with with IN cord-006870-f5w6fw6q 6341 12 a a DT cord-006870-f5w6fw6q 6341 13 smaller small JJR cord-006870-f5w6fw6q 6341 14 satellite satellite NN cord-006870-f5w6fw6q 6341 15 lesion lesion NN cord-006870-f5w6fw6q 6341 16 in in IN cord-006870-f5w6fw6q 6341 17 the the DT cord-006870-f5w6fw6q 6341 18 left left JJ cord-006870-f5w6fw6q 6341 19 insular insular JJ cord-006870-f5w6fw6q 6341 20 cortex cortex NN cord-006870-f5w6fw6q 6341 21 , , , cord-006870-f5w6fw6q 6341 22 on on IN cord-006870-f5w6fw6q 6341 23 a a DT cord-006870-f5w6fw6q 6341 24 background background NN cord-006870-f5w6fw6q 6341 25 of of IN cord-006870-f5w6fw6q 6341 26 diffuse diffuse JJ cord-006870-f5w6fw6q 6341 27 infiltrative infiltrative JJ cord-006870-f5w6fw6q 6341 28 lesion lesion NN cord-006870-f5w6fw6q 6341 29 involving involve VBG cord-006870-f5w6fw6q 6341 30 left leave VBN cord-006870-f5w6fw6q 6341 31 fronto fronto JJ cord-006870-f5w6fw6q 6341 32 - - HYPH cord-006870-f5w6fw6q 6341 33 temporal temporal JJ cord-006870-f5w6fw6q 6341 34 lobe lobe NN cord-006870-f5w6fw6q 6341 35 and and CC cord-006870-f5w6fw6q 6341 36 a a DT cord-006870-f5w6fw6q 6341 37 smaller small JJR cord-006870-f5w6fw6q 6341 38 area area NN cord-006870-f5w6fw6q 6341 39 of of IN cord-006870-f5w6fw6q 6341 40 right right JJ cord-006870-f5w6fw6q 6341 41 parafalcine parafalcine NNP cord-006870-f5w6fw6q 6341 42 frontal frontal JJ cord-006870-f5w6fw6q 6341 43 lobe lobe NN cord-006870-f5w6fw6q 6341 44 . . . cord-006870-f5w6fw6q 6342 1 Biopsy biopsy NN cord-006870-f5w6fw6q 6342 2 of of IN cord-006870-f5w6fw6q 6342 3 the the DT cord-006870-f5w6fw6q 6342 4 left left JJ cord-006870-f5w6fw6q 6342 5 frontal frontal JJ cord-006870-f5w6fw6q 6342 6 mass mass NN cord-006870-f5w6fw6q 6342 7 revealed reveal VBD cord-006870-f5w6fw6q 6342 8 it -PRON- PRP cord-006870-f5w6fw6q 6342 9 to to TO cord-006870-f5w6fw6q 6342 10 be be VB cord-006870-f5w6fw6q 6342 11 Glioblastoma Glioblastoma NNP cord-006870-f5w6fw6q 6342 12 multiforme multiforme JJ cord-006870-f5w6fw6q 6342 13 . . . cord-006870-f5w6fw6q 6343 1 This this DT cord-006870-f5w6fw6q 6343 2 is be VBZ cord-006870-f5w6fw6q 6343 3 a a DT cord-006870-f5w6fw6q 6343 4 rare rare JJ cord-006870-f5w6fw6q 6343 5 situation situation NN cord-006870-f5w6fw6q 6343 6 when when WRB cord-006870-f5w6fw6q 6343 7 a a DT cord-006870-f5w6fw6q 6343 8 previously previously RB cord-006870-f5w6fw6q 6343 9 healthy healthy JJ cord-006870-f5w6fw6q 6343 10 patient patient NN cord-006870-f5w6fw6q 6343 11 presents present VBZ cord-006870-f5w6fw6q 6343 12 with with IN cord-006870-f5w6fw6q 6343 13 new new JJ cord-006870-f5w6fw6q 6343 14 onset onset NN cord-006870-f5w6fw6q 6343 15 seizures seizure NNS cord-006870-f5w6fw6q 6343 16 and and CC cord-006870-f5w6fw6q 6343 17 already already RB cord-006870-f5w6fw6q 6343 18 has have VBZ cord-006870-f5w6fw6q 6343 19 Glioblastoma Glioblastoma NNP cord-006870-f5w6fw6q 6343 20 multiforme multiforme NN cord-006870-f5w6fw6q 6343 21 on on IN cord-006870-f5w6fw6q 6343 22 a a DT cord-006870-f5w6fw6q 6343 23 background background NN cord-006870-f5w6fw6q 6343 24 of of IN cord-006870-f5w6fw6q 6343 25 diffuse diffuse JJ cord-006870-f5w6fw6q 6343 26 astrocytoma astrocytoma NN cord-006870-f5w6fw6q 6343 27 ( ( -LRB- cord-006870-f5w6fw6q 6343 28 or or CC cord-006870-f5w6fw6q 6343 29 ' ' `` cord-006870-f5w6fw6q 6343 30 Gliomatosis gliomatosis NN cord-006870-f5w6fw6q 6343 31 cerebri cerebri NN cord-006870-f5w6fw6q 6343 32 ' ' '' cord-006870-f5w6fw6q 6343 33 ) ) -RRB- cord-006870-f5w6fw6q 6343 34 . . . cord-006870-f5w6fw6q 6344 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6344 2 post post JJ cord-006870-f5w6fw6q 6344 3 operative operative NN cord-006870-f5w6fw6q 6344 4 imaging imaging NN cord-006870-f5w6fw6q 6344 5 revealed reveal VBD cord-006870-f5w6fw6q 6344 6 disease disease NN cord-006870-f5w6fw6q 6344 7 progression progression NN cord-006870-f5w6fw6q 6344 8 with with IN cord-006870-f5w6fw6q 6344 9 increase increase NN cord-006870-f5w6fw6q 6344 10 in in IN cord-006870-f5w6fw6q 6344 11 the the DT cord-006870-f5w6fw6q 6344 12 size size NN cord-006870-f5w6fw6q 6344 13 of of IN cord-006870-f5w6fw6q 6344 14 the the DT cord-006870-f5w6fw6q 6344 15 left left JJ cord-006870-f5w6fw6q 6344 16 insular insular JJ cord-006870-f5w6fw6q 6344 17 cortical cortical JJ cord-006870-f5w6fw6q 6344 18 lesion lesion NN cord-006870-f5w6fw6q 6344 19 . . . cord-006870-f5w6fw6q 6345 1 She -PRON- PRP cord-006870-f5w6fw6q 6345 2 was be VBD cord-006870-f5w6fw6q 6345 3 discharged discharge VBN cord-006870-f5w6fw6q 6345 4 home home RB cord-006870-f5w6fw6q 6345 5 with with IN cord-006870-f5w6fw6q 6345 6 plan plan NN cord-006870-f5w6fw6q 6345 7 for for IN cord-006870-f5w6fw6q 6345 8 radiotherapy radiotherapy NN cord-006870-f5w6fw6q 6345 9 and and CC cord-006870-f5w6fw6q 6345 10 chemotherapy chemotherapy NN cord-006870-f5w6fw6q 6345 11 . . . cord-006870-f5w6fw6q 6346 1 Diffuse diffuse JJ cord-006870-f5w6fw6q 6346 2 astrocytoma astrocytoma NN cord-006870-f5w6fw6q 6346 3 with with IN cord-006870-f5w6fw6q 6346 4 Glioblastoma Glioblastoma NNP cord-006870-f5w6fw6q 6346 5 multiforme multiforme NN cord-006870-f5w6fw6q 6346 6 within within IN cord-006870-f5w6fw6q 6346 7 can can MD cord-006870-f5w6fw6q 6346 8 remain remain VB cord-006870-f5w6fw6q 6346 9 asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 6346 10 till till IN cord-006870-f5w6fw6q 6346 11 late late RB cord-006870-f5w6fw6q 6346 12 in in IN cord-006870-f5w6fw6q 6346 13 the the DT cord-006870-f5w6fw6q 6346 14 disease disease NN cord-006870-f5w6fw6q 6346 15 course course NN cord-006870-f5w6fw6q 6346 16 . . . cord-006870-f5w6fw6q 6347 1 Diffuse diffuse JJ cord-006870-f5w6fw6q 6347 2 astrocytoma astrocytoma NN cord-006870-f5w6fw6q 6347 3 ( ( -LRB- cord-006870-f5w6fw6q 6347 4 or or CC cord-006870-f5w6fw6q 6347 5 ' ' `` cord-006870-f5w6fw6q 6347 6 Gliomatosis gliomatosis NN cord-006870-f5w6fw6q 6347 7 cerebri cerebri NN cord-006870-f5w6fw6q 6347 8 ' ' '' cord-006870-f5w6fw6q 6347 9 ) ) -RRB- cord-006870-f5w6fw6q 6347 10 is be VBZ cord-006870-f5w6fw6q 6347 11 a a DT cord-006870-f5w6fw6q 6347 12 rare rare JJ cord-006870-f5w6fw6q 6347 13 disease disease NN cord-006870-f5w6fw6q 6347 14 and and CC cord-006870-f5w6fw6q 6347 15 even even RB cord-006870-f5w6fw6q 6347 16 more more RBR cord-006870-f5w6fw6q 6347 17 rare rare JJ cord-006870-f5w6fw6q 6347 18 is be VBZ cord-006870-f5w6fw6q 6347 19 to to TO cord-006870-f5w6fw6q 6347 20 have have VB cord-006870-f5w6fw6q 6347 21 this this DT cord-006870-f5w6fw6q 6347 22 remain remain VB cord-006870-f5w6fw6q 6347 23 asymptomatic asymptomatic JJ cord-006870-f5w6fw6q 6347 24 till till IN cord-006870-f5w6fw6q 6347 25 the the DT cord-006870-f5w6fw6q 6347 26 development development NN cord-006870-f5w6fw6q 6347 27 of of IN cord-006870-f5w6fw6q 6347 28 Glioblastoma Glioblastoma NNP cord-006870-f5w6fw6q 6347 29 multiforme multiforme NNP cord-006870-f5w6fw6q 6347 30 within within IN cord-006870-f5w6fw6q 6347 31 . . . cord-006870-f5w6fw6q 6348 1 This this DT cord-006870-f5w6fw6q 6348 2 particular particular JJ cord-006870-f5w6fw6q 6348 3 case case NN cord-006870-f5w6fw6q 6348 4 highlights highlight VBZ cord-006870-f5w6fw6q 6348 5 the the DT cord-006870-f5w6fw6q 6348 6 need need NN cord-006870-f5w6fw6q 6348 7 for for IN cord-006870-f5w6fw6q 6348 8 vigilance vigilance NN cord-006870-f5w6fw6q 6348 9 about about IN cord-006870-f5w6fw6q 6348 10 such such PDT cord-006870-f5w6fw6q 6348 11 a a DT cord-006870-f5w6fw6q 6348 12 possibility possibility NN cord-006870-f5w6fw6q 6348 13 , , , cord-006870-f5w6fw6q 6348 14 as as IN cord-006870-f5w6fw6q 6348 15 this this DT cord-006870-f5w6fw6q 6348 16 aggressive aggressive JJ cord-006870-f5w6fw6q 6348 17 brain brain NN cord-006870-f5w6fw6q 6348 18 tumor tumor NN cord-006870-f5w6fw6q 6348 19 carries carry VBZ cord-006870-f5w6fw6q 6348 20 a a DT cord-006870-f5w6fw6q 6348 21 grave grave JJ cord-006870-f5w6fw6q 6348 22 prognosis prognosis NN cord-006870-f5w6fw6q 6348 23 , , , cord-006870-f5w6fw6q 6348 24 especially especially RB cord-006870-f5w6fw6q 6348 25 when when WRB cord-006870-f5w6fw6q 6348 26 it -PRON- PRP cord-006870-f5w6fw6q 6348 27 develops develop VBZ cord-006870-f5w6fw6q 6348 28 on on IN cord-006870-f5w6fw6q 6348 29 background background NN cord-006870-f5w6fw6q 6348 30 of of IN cord-006870-f5w6fw6q 6348 31 a a DT cord-006870-f5w6fw6q 6348 32 diffuse diffuse JJ cord-006870-f5w6fw6q 6348 33 astrocytoma astrocytoma NN cord-006870-f5w6fw6q 6348 34 . . . cord-006870-f5w6fw6q 6349 1 Subdural subdural JJ cord-006870-f5w6fw6q 6349 2 hygromas hygromas NNPS cord-006870-f5w6fw6q 6349 3 ( ( -LRB- cord-006870-f5w6fw6q 6349 4 SDG SDG NNP cord-006870-f5w6fw6q 6349 5 ) ) -RRB- cord-006870-f5w6fw6q 6349 6 are be VBP cord-006870-f5w6fw6q 6349 7 cerebral cerebral JJ cord-006870-f5w6fw6q 6349 8 spinal spinal JJ cord-006870-f5w6fw6q 6349 9 fluid fluid JJ cord-006870-f5w6fw6q 6349 10 collections collection NNS cord-006870-f5w6fw6q 6349 11 in in IN cord-006870-f5w6fw6q 6349 12 the the DT cord-006870-f5w6fw6q 6349 13 subdural subdural JJ cord-006870-f5w6fw6q 6349 14 space space NN cord-006870-f5w6fw6q 6349 15 that that WDT cord-006870-f5w6fw6q 6349 16 may may MD cord-006870-f5w6fw6q 6349 17 occur occur VB cord-006870-f5w6fw6q 6349 18 following follow VBG cord-006870-f5w6fw6q 6349 19 trauma trauma NN cord-006870-f5w6fw6q 6349 20 . . . cord-006870-f5w6fw6q 6350 1 Decompressive decompressive JJ cord-006870-f5w6fw6q 6350 2 craniotomy craniotomy NN cord-006870-f5w6fw6q 6350 3 may may MD cord-006870-f5w6fw6q 6350 4 increase increase VB cord-006870-f5w6fw6q 6350 5 the the DT cord-006870-f5w6fw6q 6350 6 risk risk NN cord-006870-f5w6fw6q 6350 7 for for IN cord-006870-f5w6fw6q 6350 8 acute acute JJ cord-006870-f5w6fw6q 6350 9 SDG SDG NNP cord-006870-f5w6fw6q 6350 10 or or CC cord-006870-f5w6fw6q 6350 11 other other JJ cord-006870-f5w6fw6q 6350 12 forms form NNS cord-006870-f5w6fw6q 6350 13 of of IN cord-006870-f5w6fw6q 6350 14 external external JJ cord-006870-f5w6fw6q 6350 15 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 6350 16 along along IN cord-006870-f5w6fw6q 6350 17 the the DT cord-006870-f5w6fw6q 6350 18 surgical surgical JJ cord-006870-f5w6fw6q 6350 19 plane plane NN cord-006870-f5w6fw6q 6350 20 . . . cord-006870-f5w6fw6q 6351 1 While while IN cord-006870-f5w6fw6q 6351 2 these these DT cord-006870-f5w6fw6q 6351 3 are be VBP cord-006870-f5w6fw6q 6351 4 traditionally traditionally RB cord-006870-f5w6fw6q 6351 5 benign benign JJ cord-006870-f5w6fw6q 6351 6 and and CC cord-006870-f5w6fw6q 6351 7 resolve resolve VB cord-006870-f5w6fw6q 6351 8 spontaneously spontaneously RB cord-006870-f5w6fw6q 6351 9 , , , cord-006870-f5w6fw6q 6351 10 they -PRON- PRP cord-006870-f5w6fw6q 6351 11 may may MD cord-006870-f5w6fw6q 6351 12 in in IN cord-006870-f5w6fw6q 6351 13 rare rare JJ cord-006870-f5w6fw6q 6351 14 cases case NNS cord-006870-f5w6fw6q 6351 15 cause cause VBP cord-006870-f5w6fw6q 6351 16 clinical clinical JJ cord-006870-f5w6fw6q 6351 17 deterioration deterioration NN cord-006870-f5w6fw6q 6351 18 . . . cord-006870-f5w6fw6q 6352 1 We -PRON- PRP cord-006870-f5w6fw6q 6352 2 report report VBP cord-006870-f5w6fw6q 6352 3 three three CD cord-006870-f5w6fw6q 6352 4 cases case NNS cord-006870-f5w6fw6q 6352 5 . . . cord-006870-f5w6fw6q 6353 1 Cases case NNS cord-006870-f5w6fw6q 6353 2 1 1 CD cord-006870-f5w6fw6q 6353 3 and and CC cord-006870-f5w6fw6q 6353 4 2 2 CD cord-006870-f5w6fw6q 6353 5 were be VBD cord-006870-f5w6fw6q 6353 6 alcoholic alcoholic JJ cord-006870-f5w6fw6q 6353 7 men man NNS cord-006870-f5w6fw6q 6353 8 aged age VBN cord-006870-f5w6fw6q 6353 9 54 54 CD cord-006870-f5w6fw6q 6353 10 and and CC cord-006870-f5w6fw6q 6353 11 69 69 CD cord-006870-f5w6fw6q 6353 12 , , , cord-006870-f5w6fw6q 6353 13 respectively respectively RB cord-006870-f5w6fw6q 6353 14 , , , cord-006870-f5w6fw6q 6353 15 who who WP cord-006870-f5w6fw6q 6353 16 suffered suffer VBD cord-006870-f5w6fw6q 6353 17 severe severe JJ cord-006870-f5w6fw6q 6353 18 traumatic traumatic JJ cord-006870-f5w6fw6q 6353 19 brain brain NN cord-006870-f5w6fw6q 6353 20 injury injury NN cord-006870-f5w6fw6q 6353 21 ( ( -LRB- cord-006870-f5w6fw6q 6353 22 TBI TBI NNP cord-006870-f5w6fw6q 6353 23 ) ) -RRB- cord-006870-f5w6fw6q 6353 24 following following NN cord-006870-f5w6fw6q 6353 25 falls fall VBZ cord-006870-f5w6fw6q 6353 26 while while IN cord-006870-f5w6fw6q 6353 27 intoxicated intoxicate VBN cord-006870-f5w6fw6q 6353 28 . . . cord-006870-f5w6fw6q 6354 1 They -PRON- PRP cord-006870-f5w6fw6q 6354 2 had have VBD cord-006870-f5w6fw6q 6354 3 early early JJ cord-006870-f5w6fw6q 6354 4 clinical clinical JJ cord-006870-f5w6fw6q 6354 5 deterioration deterioration NN cord-006870-f5w6fw6q 6354 6 prompting prompt VBG cord-006870-f5w6fw6q 6354 7 emergent emergent JJ cord-006870-f5w6fw6q 6354 8 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 6354 9 for for IN cord-006870-f5w6fw6q 6354 10 left left JJ cord-006870-f5w6fw6q 6354 11 - - HYPH cord-006870-f5w6fw6q 6354 12 sided sided JJ cord-006870-f5w6fw6q 6354 13 SDH SDH NNP cord-006870-f5w6fw6q 6354 14 with with IN cord-006870-f5w6fw6q 6354 15 midline midline JJ cord-006870-f5w6fw6q 6354 16 shift shift NN cord-006870-f5w6fw6q 6354 17 ( ( -LRB- cord-006870-f5w6fw6q 6354 18 MLS MLS NNP cord-006870-f5w6fw6q 6354 19 ) ) -RRB- cord-006870-f5w6fw6q 6354 20 . . . cord-006870-f5w6fw6q 6355 1 Case case NN cord-006870-f5w6fw6q 6355 2 1 1 CD cord-006870-f5w6fw6q 6355 3 clinically clinically RB cord-006870-f5w6fw6q 6355 4 worsened worsen VBD cord-006870-f5w6fw6q 6355 5 on on IN cord-006870-f5w6fw6q 6355 6 postoperative postoperative JJ cord-006870-f5w6fw6q 6355 7 day day NN cord-006870-f5w6fw6q 6355 8 ( ( -LRB- cord-006870-f5w6fw6q 6355 9 POD POD NNP cord-006870-f5w6fw6q 6355 10 ) ) -RRB- cord-006870-f5w6fw6q 6355 11 6 6 CD cord-006870-f5w6fw6q 6355 12 with with IN cord-006870-f5w6fw6q 6355 13 posturing posturing NN cord-006870-f5w6fw6q 6355 14 , , , cord-006870-f5w6fw6q 6355 15 decreased decrease VBD cord-006870-f5w6fw6q 6355 16 pupillary pupillary JJ cord-006870-f5w6fw6q 6355 17 responses response NNS cord-006870-f5w6fw6q 6355 18 , , , cord-006870-f5w6fw6q 6355 19 and and CC cord-006870-f5w6fw6q 6355 20 new new JJ cord-006870-f5w6fw6q 6355 21 - - HYPH cord-006870-f5w6fw6q 6355 22 onset onset NN cord-006870-f5w6fw6q 6355 23 seizures seizure NNS cord-006870-f5w6fw6q 6355 24 . . . cord-006870-f5w6fw6q 6356 1 New new JJ cord-006870-f5w6fw6q 6356 2 bilateral bilateral JJ cord-006870-f5w6fw6q 6356 3 , , , cord-006870-f5w6fw6q 6356 4 extensive extensive JJ cord-006870-f5w6fw6q 6356 5 subdural subdural JJ cord-006870-f5w6fw6q 6356 6 hygromas hygromas NNPS cord-006870-f5w6fw6q 6356 7 were be VBD cord-006870-f5w6fw6q 6356 8 noted note VBN cord-006870-f5w6fw6q 6356 9 , , , cord-006870-f5w6fw6q 6356 10 enlarging enlarge VBG cord-006870-f5w6fw6q 6356 11 over over IN cord-006870-f5w6fw6q 6356 12 serial serial JJ cord-006870-f5w6fw6q 6356 13 CT CT NNP cord-006870-f5w6fw6q 6356 14 scans scan NNS cord-006870-f5w6fw6q 6356 15 up up IN cord-006870-f5w6fw6q 6356 16 to to IN cord-006870-f5w6fw6q 6356 17 1-cm 1-cm CD cord-006870-f5w6fw6q 6356 18 with with IN cord-006870-f5w6fw6q 6356 19 progressive progressive JJ cord-006870-f5w6fw6q 6356 20 mass mass NN cord-006870-f5w6fw6q 6356 21 effect effect NN cord-006870-f5w6fw6q 6356 22 . . . cord-006870-f5w6fw6q 6357 1 Uncal uncal JJ cord-006870-f5w6fw6q 6357 2 herniation herniation NN cord-006870-f5w6fw6q 6357 3 and and CC cord-006870-f5w6fw6q 6357 4 downward downward JJ cord-006870-f5w6fw6q 6357 5 brainstem brainstem NN cord-006870-f5w6fw6q 6357 6 displacement displacement NN cord-006870-f5w6fw6q 6357 7 occurred occur VBN cord-006870-f5w6fw6q 6357 8 by by IN cord-006870-f5w6fw6q 6357 9 POD8 POD8 NNP cord-006870-f5w6fw6q 6357 10 despite despite IN cord-006870-f5w6fw6q 6357 11 external external JJ cord-006870-f5w6fw6q 6357 12 ventricular ventricular JJ cord-006870-f5w6fw6q 6357 13 drainage drainage NN cord-006870-f5w6fw6q 6357 14 . . . cord-006870-f5w6fw6q 6358 1 Case case NN cord-006870-f5w6fw6q 6358 2 2 2 CD cord-006870-f5w6fw6q 6358 3 deteriorated deteriorate VBD cord-006870-f5w6fw6q 6358 4 on on IN cord-006870-f5w6fw6q 6358 5 POD4 POD4 NNP cord-006870-f5w6fw6q 6358 6 with with IN cord-006870-f5w6fw6q 6358 7 fluctuating fluctuate VBG cord-006870-f5w6fw6q 6358 8 exam exam NN cord-006870-f5w6fw6q 6358 9 and and CC cord-006870-f5w6fw6q 6358 10 newonset newonset NN cord-006870-f5w6fw6q 6358 11 seizures seizure NNS cord-006870-f5w6fw6q 6358 12 . . . cord-006870-f5w6fw6q 6359 1 Imaging imaging NN cord-006870-f5w6fw6q 6359 2 revealed reveal VBD cord-006870-f5w6fw6q 6359 3 new new JJ cord-006870-f5w6fw6q 6359 4 subgaleal subgaleal JJ cord-006870-f5w6fw6q 6359 5 fluid fluid NN cord-006870-f5w6fw6q 6359 6 collection collection NN cord-006870-f5w6fw6q 6359 7 measuring measure VBG cord-006870-f5w6fw6q 6359 8 1.8-cm 1.8-cm CD cord-006870-f5w6fw6q 6359 9 and and CC cord-006870-f5w6fw6q 6359 10 a a DT cord-006870-f5w6fw6q 6359 11 contralateral contralateral JJ cord-006870-f5w6fw6q 6359 12 SDG SDG NNP cord-006870-f5w6fw6q 6359 13 . . . cord-006870-f5w6fw6q 6360 1 On on IN cord-006870-f5w6fw6q 6360 2 POD8 POD8 NNP cord-006870-f5w6fw6q 6360 3 , , , cord-006870-f5w6fw6q 6360 4 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 6360 5 was be VBD cord-006870-f5w6fw6q 6360 6 performed perform VBN cord-006870-f5w6fw6q 6360 7 for for IN cord-006870-f5w6fw6q 6360 8 new new JJ cord-006870-f5w6fw6q 6360 9 MLS MLS NNP cord-006870-f5w6fw6q 6360 10 from from IN cord-006870-f5w6fw6q 6360 11 enlarging enlarge VBG cord-006870-f5w6fw6q 6360 12 fluid fluid NN cord-006870-f5w6fw6q 6360 13 and and CC cord-006870-f5w6fw6q 6360 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6360 15 in in IN cord-006870-f5w6fw6q 6360 16 extradural extradural JJ cord-006870-f5w6fw6q 6360 17 component component NN cord-006870-f5w6fw6q 6360 18 . . . cord-006870-f5w6fw6q 6361 1 Both both DT cord-006870-f5w6fw6q 6361 2 died die VBD cord-006870-f5w6fw6q 6361 3 shortly shortly RB cord-006870-f5w6fw6q 6361 4 after after IN cord-006870-f5w6fw6q 6361 5 withdrawal withdrawal NN cord-006870-f5w6fw6q 6361 6 - - HYPH cord-006870-f5w6fw6q 6361 7 of of IN cord-006870-f5w6fw6q 6361 8 - - HYPH cord-006870-f5w6fw6q 6361 9 care care NN cord-006870-f5w6fw6q 6361 10 . . . cord-006870-f5w6fw6q 6362 1 Case case NN cord-006870-f5w6fw6q 6362 2 3 3 CD cord-006870-f5w6fw6q 6362 3 was be VBD cord-006870-f5w6fw6q 6362 4 a a DT cord-006870-f5w6fw6q 6362 5 68 68 CD cord-006870-f5w6fw6q 6362 6 year year NN cord-006870-f5w6fw6q 6362 7 - - HYPH cord-006870-f5w6fw6q 6362 8 old old JJ cord-006870-f5w6fw6q 6362 9 man man NN cord-006870-f5w6fw6q 6362 10 with with IN cord-006870-f5w6fw6q 6362 11 dural dural JJ cord-006870-f5w6fw6q 6362 12 arteriovenous arteriovenous JJ cord-006870-f5w6fw6q 6362 13 fistula fistula NN cord-006870-f5w6fw6q 6362 14 who who WP cord-006870-f5w6fw6q 6362 15 presented present VBD cord-006870-f5w6fw6q 6362 16 with with IN cord-006870-f5w6fw6q 6362 17 spontaneous spontaneous JJ cord-006870-f5w6fw6q 6362 18 left left JJ cord-006870-f5w6fw6q 6362 19 - - HYPH cord-006870-f5w6fw6q 6362 20 sided sided JJ cord-006870-f5w6fw6q 6362 21 SDH SDH NNP cord-006870-f5w6fw6q 6362 22 and and CC cord-006870-f5w6fw6q 6362 23 underwent undergo VBD cord-006870-f5w6fw6q 6362 24 left leave VBN cord-006870-f5w6fw6q 6362 25 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 6362 26 . . . cord-006870-f5w6fw6q 6363 1 On on IN cord-006870-f5w6fw6q 6363 2 POD3 POD3 NNPS cord-006870-f5w6fw6q 6363 3 , , , cord-006870-f5w6fw6q 6363 4 he -PRON- PRP cord-006870-f5w6fw6q 6363 5 had have VBD cord-006870-f5w6fw6q 6363 6 new new JJ cord-006870-f5w6fw6q 6363 7 - - HYPH cord-006870-f5w6fw6q 6363 8 onset onset NN cord-006870-f5w6fw6q 6363 9 seizures seizure NNS cord-006870-f5w6fw6q 6363 10 and and CC cord-006870-f5w6fw6q 6363 11 new new JJ cord-006870-f5w6fw6q 6363 12 bilateral bilateral JJ cord-006870-f5w6fw6q 6363 13 SDG SDG NNP cord-006870-f5w6fw6q 6363 14 measuring measure VBG cord-006870-f5w6fw6q 6363 15 1.5-cm 1.5-cm CD cord-006870-f5w6fw6q 6363 16 on on IN cord-006870-f5w6fw6q 6363 17 the the DT cord-006870-f5w6fw6q 6363 18 left left NN cord-006870-f5w6fw6q 6363 19 and and CC cord-006870-f5w6fw6q 6363 20 0.5-cm 0.5-cm CD cord-006870-f5w6fw6q 6364 1 on on IN cord-006870-f5w6fw6q 6364 2 the the DT cord-006870-f5w6fw6q 6364 3 right right NN cord-006870-f5w6fw6q 6364 4 without without IN cord-006870-f5w6fw6q 6364 5 mass mass JJ cord-006870-f5w6fw6q 6364 6 effect effect NN cord-006870-f5w6fw6q 6364 7 . . . cord-006870-f5w6fw6q 6365 1 Two two CD cord-006870-f5w6fw6q 6365 2 days day NNS cord-006870-f5w6fw6q 6365 3 later later RB cord-006870-f5w6fw6q 6365 4 ; ; : cord-006870-f5w6fw6q 6365 5 the the DT cord-006870-f5w6fw6q 6365 6 right right JJ cord-006870-f5w6fw6q 6365 7 SDG SDG NNP cord-006870-f5w6fw6q 6365 8 grew grow VBD cord-006870-f5w6fw6q 6365 9 to to IN cord-006870-f5w6fw6q 6365 10 2.8-cm 2.8-cm CD cord-006870-f5w6fw6q 6365 11 causing cause VBG cord-006870-f5w6fw6q 6365 12 significant significant JJ cord-006870-f5w6fw6q 6365 13 mass mass NN cord-006870-f5w6fw6q 6365 14 effect effect NN cord-006870-f5w6fw6q 6365 15 . . . cord-006870-f5w6fw6q 6366 1 He -PRON- PRP cord-006870-f5w6fw6q 6366 2 recovered recover VBD cord-006870-f5w6fw6q 6366 3 after after IN cord-006870-f5w6fw6q 6366 4 burr burr NN cord-006870-f5w6fw6q 6366 5 - - HYPH cord-006870-f5w6fw6q 6366 6 hole hole NN cord-006870-f5w6fw6q 6366 7 evacuation evacuation NN cord-006870-f5w6fw6q 6366 8 and and CC cord-006870-f5w6fw6q 6366 9 temporary temporary JJ cord-006870-f5w6fw6q 6366 10 subdural subdural JJ cord-006870-f5w6fw6q 6366 11 drain drain NN cord-006870-f5w6fw6q 6366 12 placement placement NN cord-006870-f5w6fw6q 6366 13 . . . cord-006870-f5w6fw6q 6367 1 SDG SDG NNP cord-006870-f5w6fw6q 6367 2 following follow VBG cord-006870-f5w6fw6q 6367 3 SDH SDH NNP cord-006870-f5w6fw6q 6367 4 evacuation evacuation NN cord-006870-f5w6fw6q 6367 5 can can MD cord-006870-f5w6fw6q 6367 6 have have VB cord-006870-f5w6fw6q 6367 7 a a DT cord-006870-f5w6fw6q 6367 8 malignant malignant JJ cord-006870-f5w6fw6q 6367 9 course course NN cord-006870-f5w6fw6q 6367 10 , , , cord-006870-f5w6fw6q 6367 11 causing cause VBG cord-006870-f5w6fw6q 6367 12 clinical clinical JJ cord-006870-f5w6fw6q 6367 13 deterioration deterioration NN cord-006870-f5w6fw6q 6367 14 without without IN cord-006870-f5w6fw6q 6367 15 prompt prompt JJ cord-006870-f5w6fw6q 6367 16 recognition recognition NN cord-006870-f5w6fw6q 6367 17 and and CC cord-006870-f5w6fw6q 6367 18 CSF CSF NNP cord-006870-f5w6fw6q 6367 19 diversion diversion NN cord-006870-f5w6fw6q 6367 20 . . . cord-006870-f5w6fw6q 6368 1 All all DT cord-006870-f5w6fw6q 6368 2 patients patient NNS cord-006870-f5w6fw6q 6368 3 had have VBD cord-006870-f5w6fw6q 6368 4 large large JJ cord-006870-f5w6fw6q 6368 5 volume volume NN cord-006870-f5w6fw6q 6368 6 SDH SDH NNP cord-006870-f5w6fw6q 6368 7 and and CC cord-006870-f5w6fw6q 6368 8 two two CD cord-006870-f5w6fw6q 6368 9 were be VBD cord-006870-f5w6fw6q 6368 10 alcoholic alcoholic JJ cord-006870-f5w6fw6q 6368 11 ; ; : cord-006870-f5w6fw6q 6368 12 larger large JJR cord-006870-f5w6fw6q 6368 13 prospective prospective JJ cord-006870-f5w6fw6q 6368 14 cohorts cohort NNS cord-006870-f5w6fw6q 6368 15 are be VBP cord-006870-f5w6fw6q 6368 16 required require VBN cord-006870-f5w6fw6q 6368 17 to to TO cord-006870-f5w6fw6q 6368 18 identify identify VB cord-006870-f5w6fw6q 6368 19 risk risk NN cord-006870-f5w6fw6q 6368 20 factors factor NNS cord-006870-f5w6fw6q 6368 21 . . . cord-006870-f5w6fw6q 6369 1 Seizures seizure NNS cord-006870-f5w6fw6q 6369 2 may may MD cord-006870-f5w6fw6q 6369 3 be be VB cord-006870-f5w6fw6q 6369 4 an an DT cord-006870-f5w6fw6q 6369 5 early early JJ cord-006870-f5w6fw6q 6369 6 clinical clinical JJ cord-006870-f5w6fw6q 6369 7 sign sign NN cord-006870-f5w6fw6q 6369 8 . . . cord-006870-f5w6fw6q 6370 1 Moyamoya Moyamoya NNP cord-006870-f5w6fw6q 6370 2 disease disease NN cord-006870-f5w6fw6q 6370 3 is be VBZ cord-006870-f5w6fw6q 6370 4 an an DT cord-006870-f5w6fw6q 6370 5 intracranial intracranial JJ cord-006870-f5w6fw6q 6370 6 vasculopathy vasculopathy NN cord-006870-f5w6fw6q 6370 7 that that WDT cord-006870-f5w6fw6q 6370 8 results result VBZ cord-006870-f5w6fw6q 6370 9 in in IN cord-006870-f5w6fw6q 6370 10 stenosis stenosis NN cord-006870-f5w6fw6q 6370 11 of of IN cord-006870-f5w6fw6q 6370 12 bilateral bilateral JJ cord-006870-f5w6fw6q 6370 13 internal internal JJ cord-006870-f5w6fw6q 6370 14 carotid carotid JJ cord-006870-f5w6fw6q 6370 15 arteries artery NNS cord-006870-f5w6fw6q 6370 16 with with IN cord-006870-f5w6fw6q 6370 17 subsequent subsequent JJ cord-006870-f5w6fw6q 6370 18 development development NN cord-006870-f5w6fw6q 6370 19 of of IN cord-006870-f5w6fw6q 6370 20 extensive extensive JJ cord-006870-f5w6fw6q 6370 21 collateralization collateralization NN cord-006870-f5w6fw6q 6370 22 . . . cord-006870-f5w6fw6q 6371 1 The the DT cord-006870-f5w6fw6q 6371 2 diagnostic diagnostic JJ cord-006870-f5w6fw6q 6371 3 criteria criterion NNS cord-006870-f5w6fw6q 6371 4 for for IN cord-006870-f5w6fw6q 6371 5 moyamoya moyamoya NNP cord-006870-f5w6fw6q 6371 6 disease disease NNP cord-006870-f5w6fw6q 6371 7 are be VBP cord-006870-f5w6fw6q 6371 8 well well RB cord-006870-f5w6fw6q 6371 9 established establish VBN cord-006870-f5w6fw6q 6371 10 and and CC cord-006870-f5w6fw6q 6371 11 generally generally RB cord-006870-f5w6fw6q 6371 12 accepted accept VBN cord-006870-f5w6fw6q 6371 13 , , , cord-006870-f5w6fw6q 6371 14 yet yet CC cord-006870-f5w6fw6q 6371 15 reaching reach VBG cord-006870-f5w6fw6q 6371 16 the the DT cord-006870-f5w6fw6q 6371 17 diagnosis diagnosis NN cord-006870-f5w6fw6q 6371 18 can can MD cord-006870-f5w6fw6q 6371 19 be be VB cord-006870-f5w6fw6q 6371 20 challenging challenging JJ cord-006870-f5w6fw6q 6371 21 in in IN cord-006870-f5w6fw6q 6371 22 some some DT cord-006870-f5w6fw6q 6371 23 cases case NNS cord-006870-f5w6fw6q 6371 24 . . . cord-006870-f5w6fw6q 6372 1 Herein herein RB cord-006870-f5w6fw6q 6372 2 , , , cord-006870-f5w6fw6q 6372 3 we -PRON- PRP cord-006870-f5w6fw6q 6372 4 present present VBP cord-006870-f5w6fw6q 6372 5 an an DT cord-006870-f5w6fw6q 6372 6 unusual unusual JJ cord-006870-f5w6fw6q 6372 7 case case NN cord-006870-f5w6fw6q 6372 8 of of IN cord-006870-f5w6fw6q 6372 9 progressive progressive JJ cord-006870-f5w6fw6q 6372 10 cerebral cerebral JJ cord-006870-f5w6fw6q 6372 11 vasospasm vasospasm NN cord-006870-f5w6fw6q 6372 12 triggered trigger VBN cord-006870-f5w6fw6q 6372 13 by by IN cord-006870-f5w6fw6q 6372 14 pituitary pituitary JJ cord-006870-f5w6fw6q 6372 15 apoplexy apoplexy NN cord-006870-f5w6fw6q 6372 16 that that WDT cord-006870-f5w6fw6q 6372 17 led lead VBD cord-006870-f5w6fw6q 6372 18 to to IN cord-006870-f5w6fw6q 6372 19 a a DT cord-006870-f5w6fw6q 6372 20 delay delay NN cord-006870-f5w6fw6q 6372 21 in in IN cord-006870-f5w6fw6q 6372 22 the the DT cord-006870-f5w6fw6q 6372 23 underlying underlie VBG cord-006870-f5w6fw6q 6372 24 diagnosis diagnosis NN cord-006870-f5w6fw6q 6372 25 of of IN cord-006870-f5w6fw6q 6372 26 moyamoya moyamoya NNP cord-006870-f5w6fw6q 6372 27 disease disease NNP cord-006870-f5w6fw6q 6372 28 . . . cord-006870-f5w6fw6q 6373 1 Case case NN cord-006870-f5w6fw6q 6373 2 report report NN cord-006870-f5w6fw6q 6373 3 . . . cord-006870-f5w6fw6q 6374 1 A a DT cord-006870-f5w6fw6q 6374 2 53-year 53-year JJ cord-006870-f5w6fw6q 6374 3 - - HYPH cord-006870-f5w6fw6q 6374 4 old old JJ cord-006870-f5w6fw6q 6374 5 female female NN cord-006870-f5w6fw6q 6374 6 with with IN cord-006870-f5w6fw6q 6374 7 hyperlipidemia hyperlipidemia NN cord-006870-f5w6fw6q 6374 8 presented present VBN cord-006870-f5w6fw6q 6374 9 to to IN cord-006870-f5w6fw6q 6374 10 the the DT cord-006870-f5w6fw6q 6374 11 emergency emergency NN cord-006870-f5w6fw6q 6374 12 department department NN cord-006870-f5w6fw6q 6374 13 with with IN cord-006870-f5w6fw6q 6374 14 a a DT cord-006870-f5w6fw6q 6374 15 bifrontal bifrontal JJ cord-006870-f5w6fw6q 6374 16 headache headache NN cord-006870-f5w6fw6q 6374 17 , , , cord-006870-f5w6fw6q 6374 18 right right JJ cord-006870-f5w6fw6q 6374 19 - - HYPH cord-006870-f5w6fw6q 6374 20 sided sided JJ cord-006870-f5w6fw6q 6374 21 weakness weakness NN cord-006870-f5w6fw6q 6374 22 , , , cord-006870-f5w6fw6q 6374 23 and and CC cord-006870-f5w6fw6q 6374 24 dysarthria dysarthria NN cord-006870-f5w6fw6q 6374 25 . . . cord-006870-f5w6fw6q 6375 1 CT CT NNP cord-006870-f5w6fw6q 6375 2 angiogram angiogram NN cord-006870-f5w6fw6q 6375 3 showed show VBD cord-006870-f5w6fw6q 6375 4 extensive extensive JJ cord-006870-f5w6fw6q 6375 5 multifocal multifocal JJ cord-006870-f5w6fw6q 6375 6 narrowing narrowing NN cord-006870-f5w6fw6q 6375 7 of of IN cord-006870-f5w6fw6q 6375 8 the the DT cord-006870-f5w6fw6q 6375 9 bilateral bilateral JJ cord-006870-f5w6fw6q 6375 10 supraclinoid supraclinoid NN cord-006870-f5w6fw6q 6375 11 ICAs ICAs NNP cord-006870-f5w6fw6q 6375 12 , , , cord-006870-f5w6fw6q 6375 13 proximal proximal JJ cord-006870-f5w6fw6q 6375 14 ACA ACA NNP cord-006870-f5w6fw6q 6375 15 / / SYM cord-006870-f5w6fw6q 6375 16 MCAs mca NNS cord-006870-f5w6fw6q 6375 17 , , , cord-006870-f5w6fw6q 6375 18 and and CC cord-006870-f5w6fw6q 6375 19 posterior posterior JJ cord-006870-f5w6fw6q 6375 20 circulation circulation NN cord-006870-f5w6fw6q 6375 21 . . . cord-006870-f5w6fw6q 6376 1 MRI MRI NNP cord-006870-f5w6fw6q 6376 2 brain brain NN cord-006870-f5w6fw6q 6376 3 revealed reveal VBD cord-006870-f5w6fw6q 6376 4 a a DT cord-006870-f5w6fw6q 6376 5 left left JJ cord-006870-f5w6fw6q 6376 6 insular insular JJ cord-006870-f5w6fw6q 6376 7 stroke stroke NN cord-006870-f5w6fw6q 6376 8 as as RB cord-006870-f5w6fw6q 6376 9 well well RB cord-006870-f5w6fw6q 6376 10 as as IN cord-006870-f5w6fw6q 6376 11 a a DT cord-006870-f5w6fw6q 6376 12 sellar sellar JJ cord-006870-f5w6fw6q 6376 13 mass mass NN cord-006870-f5w6fw6q 6376 14 with with IN cord-006870-f5w6fw6q 6376 15 a a DT cord-006870-f5w6fw6q 6376 16 central central JJ cord-006870-f5w6fw6q 6376 17 hemorrhagic hemorrhagic JJ cord-006870-f5w6fw6q 6376 18 component component NN cord-006870-f5w6fw6q 6376 19 . . . cord-006870-f5w6fw6q 6377 1 MR MR NNP cord-006870-f5w6fw6q 6377 2 perfusion perfusion NN cord-006870-f5w6fw6q 6377 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6377 4 decreased decrease VBD cord-006870-f5w6fw6q 6377 5 perfusion perfusion NN cord-006870-f5w6fw6q 6377 6 in in IN cord-006870-f5w6fw6q 6377 7 the the DT cord-006870-f5w6fw6q 6377 8 right right JJ cord-006870-f5w6fw6q 6377 9 hemisphere hemisphere NN cord-006870-f5w6fw6q 6377 10 . . . cord-006870-f5w6fw6q 6378 1 Lumbar lumbar JJ cord-006870-f5w6fw6q 6378 2 puncture puncture NN cord-006870-f5w6fw6q 6378 3 and and CC cord-006870-f5w6fw6q 6378 4 extensive extensive JJ cord-006870-f5w6fw6q 6378 5 vasculitic vasculitic JJ cord-006870-f5w6fw6q 6378 6 workup workup NN cord-006870-f5w6fw6q 6378 7 was be VBD cord-006870-f5w6fw6q 6378 8 unremarkable unremarkable JJ cord-006870-f5w6fw6q 6378 9 . . . cord-006870-f5w6fw6q 6379 1 Endocrine endocrine NN cord-006870-f5w6fw6q 6379 2 studies study NNS cord-006870-f5w6fw6q 6379 3 were be VBD cord-006870-f5w6fw6q 6379 4 notable notable JJ cord-006870-f5w6fw6q 6379 5 for for IN cord-006870-f5w6fw6q 6379 6 elevated elevated JJ cord-006870-f5w6fw6q 6379 7 prolactin prolactin NN cord-006870-f5w6fw6q 6379 8 with with IN cord-006870-f5w6fw6q 6379 9 low low JJ cord-006870-f5w6fw6q 6379 10 FSH fsh NN cord-006870-f5w6fw6q 6379 11 and and CC cord-006870-f5w6fw6q 6379 12 LH LH NNP cord-006870-f5w6fw6q 6379 13 levels level NNS cord-006870-f5w6fw6q 6379 14 . . . cord-006870-f5w6fw6q 6380 1 Despite despite IN cord-006870-f5w6fw6q 6380 2 protracted protracted JJ cord-006870-f5w6fw6q 6380 3 blood blood NN cord-006870-f5w6fw6q 6380 4 pressure pressure NN cord-006870-f5w6fw6q 6380 5 augmentation augmentation NN cord-006870-f5w6fw6q 6380 6 strategies strategy NNS cord-006870-f5w6fw6q 6380 7 , , , cord-006870-f5w6fw6q 6380 8 the the DT cord-006870-f5w6fw6q 6380 9 patient patient NN cord-006870-f5w6fw6q 6380 10 continued continue VBD cord-006870-f5w6fw6q 6380 11 to to TO cord-006870-f5w6fw6q 6380 12 experience experience VB cord-006870-f5w6fw6q 6380 13 progressive progressive JJ cord-006870-f5w6fw6q 6380 14 infarcts infarct NNS cord-006870-f5w6fw6q 6380 15 in in IN cord-006870-f5w6fw6q 6380 16 the the DT cord-006870-f5w6fw6q 6380 17 left left JJ cord-006870-f5w6fw6q 6380 18 MCA MCA NNP cord-006870-f5w6fw6q 6380 19 / / SYM cord-006870-f5w6fw6q 6380 20 ACA ACA NNP cord-006870-f5w6fw6q 6380 21 territory territory NN cord-006870-f5w6fw6q 6380 22 . . . cord-006870-f5w6fw6q 6381 1 Repeat repeat NN cord-006870-f5w6fw6q 6381 2 CT CT NNP cord-006870-f5w6fw6q 6381 3 angiogram angiogram NN cord-006870-f5w6fw6q 6381 4 showed show VBD cord-006870-f5w6fw6q 6381 5 progression progression NN cord-006870-f5w6fw6q 6381 6 of of IN cord-006870-f5w6fw6q 6381 7 vasculopathy vasculopathy NNP cord-006870-f5w6fw6q 6381 8 , , , cord-006870-f5w6fw6q 6381 9 and and CC cord-006870-f5w6fw6q 6381 10 transcranial transcranial JJ cord-006870-f5w6fw6q 6381 11 Doppler Doppler NNP cord-006870-f5w6fw6q 6381 12 studies study NNS cord-006870-f5w6fw6q 6381 13 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6381 14 worsening worsen VBG cord-006870-f5w6fw6q 6381 15 vasospasm vasospasm NN cord-006870-f5w6fw6q 6381 16 of of IN cord-006870-f5w6fw6q 6381 17 the the DT cord-006870-f5w6fw6q 6381 18 right right JJ cord-006870-f5w6fw6q 6381 19 MCA MCA NNP cord-006870-f5w6fw6q 6381 20 and and CC cord-006870-f5w6fw6q 6381 21 left leave VBD cord-006870-f5w6fw6q 6381 22 PCA PCA NNP cord-006870-f5w6fw6q 6381 23 arteries artery NNS cord-006870-f5w6fw6q 6381 24 . . . cord-006870-f5w6fw6q 6382 1 The the DT cord-006870-f5w6fw6q 6382 2 patient patient NN cord-006870-f5w6fw6q 6382 3 received receive VBD cord-006870-f5w6fw6q 6382 4 corticosteroids corticosteroid NNS cord-006870-f5w6fw6q 6382 5 given give VBN cord-006870-f5w6fw6q 6382 6 concern concern NN cord-006870-f5w6fw6q 6382 7 for for IN cord-006870-f5w6fw6q 6382 8 apoplexy apoplexy NN cord-006870-f5w6fw6q 6382 9 , , , cord-006870-f5w6fw6q 6382 10 and and CC cord-006870-f5w6fw6q 6382 11 was be VBD cord-006870-f5w6fw6q 6382 12 maintained maintain VBN cord-006870-f5w6fw6q 6382 13 on on IN cord-006870-f5w6fw6q 6382 14 aspirin aspirin NN cord-006870-f5w6fw6q 6382 15 and and CC cord-006870-f5w6fw6q 6382 16 verapamil verapamil NN cord-006870-f5w6fw6q 6382 17 . . . cord-006870-f5w6fw6q 6383 1 Given give VBN cord-006870-f5w6fw6q 6383 2 the the DT cord-006870-f5w6fw6q 6383 3 aggressive aggressive JJ cord-006870-f5w6fw6q 6383 4 nature nature NN cord-006870-f5w6fw6q 6383 5 of of IN cord-006870-f5w6fw6q 6383 6 her -PRON- PRP$ cord-006870-f5w6fw6q 6383 7 vasculopathy vasculopathy NNP cord-006870-f5w6fw6q 6383 8 , , , cord-006870-f5w6fw6q 6383 9 the the DT cord-006870-f5w6fw6q 6383 10 patient patient NN cord-006870-f5w6fw6q 6383 11 underwent undergo VBD cord-006870-f5w6fw6q 6383 12 conventional conventional JJ cord-006870-f5w6fw6q 6383 13 angiography angiography NN cord-006870-f5w6fw6q 6383 14 two two CD cord-006870-f5w6fw6q 6383 15 weeks week NNS cord-006870-f5w6fw6q 6383 16 later later RB cord-006870-f5w6fw6q 6383 17 , , , cord-006870-f5w6fw6q 6383 18 which which WDT cord-006870-f5w6fw6q 6383 19 revealed reveal VBD cord-006870-f5w6fw6q 6383 20 bilateral bilateral JJ cord-006870-f5w6fw6q 6383 21 Suzuki Suzuki NNP cord-006870-f5w6fw6q 6383 22 grade grade NN cord-006870-f5w6fw6q 6383 23 III III NNP cord-006870-f5w6fw6q 6383 24 moyamoya moyamoya NNS cord-006870-f5w6fw6q 6383 25 . . . cord-006870-f5w6fw6q 6384 1 Following follow VBG cord-006870-f5w6fw6q 6384 2 this this DT cord-006870-f5w6fw6q 6384 3 diagnosis diagnosis NN cord-006870-f5w6fw6q 6384 4 , , , cord-006870-f5w6fw6q 6384 5 she -PRON- PRP cord-006870-f5w6fw6q 6384 6 received receive VBD cord-006870-f5w6fw6q 6384 7 bilateral bilateral JJ cord-006870-f5w6fw6q 6384 8 STA STA NNP cord-006870-f5w6fw6q 6384 9 - - HYPH cord-006870-f5w6fw6q 6384 10 MCA MCA NNP cord-006870-f5w6fw6q 6384 11 bypass bypass NN cord-006870-f5w6fw6q 6384 12 surgeries surgery NNS cord-006870-f5w6fw6q 6384 13 . . . cord-006870-f5w6fw6q 6385 1 It -PRON- PRP cord-006870-f5w6fw6q 6385 2 is be VBZ cord-006870-f5w6fw6q 6385 3 important important JJ cord-006870-f5w6fw6q 6385 4 to to TO cord-006870-f5w6fw6q 6385 5 revisit revisit VB cord-006870-f5w6fw6q 6385 6 the the DT cord-006870-f5w6fw6q 6385 7 differential differential JJ cord-006870-f5w6fw6q 6385 8 diagnosis diagnosis NN cord-006870-f5w6fw6q 6385 9 of of IN cord-006870-f5w6fw6q 6385 10 cerebral cerebral JJ cord-006870-f5w6fw6q 6385 11 vasospasm vasospasm NN cord-006870-f5w6fw6q 6385 12 when when WRB cord-006870-f5w6fw6q 6385 13 the the DT cord-006870-f5w6fw6q 6385 14 clinical clinical JJ cord-006870-f5w6fw6q 6385 15 course course NN cord-006870-f5w6fw6q 6385 16 does do VBZ cord-006870-f5w6fw6q 6385 17 not not RB cord-006870-f5w6fw6q 6385 18 conform conform VB cord-006870-f5w6fw6q 6385 19 to to IN cord-006870-f5w6fw6q 6385 20 expectations expectation NNS cord-006870-f5w6fw6q 6385 21 . . . cord-006870-f5w6fw6q 6386 1 This this DT cord-006870-f5w6fw6q 6386 2 case case NN cord-006870-f5w6fw6q 6386 3 highlights highlight VBZ cord-006870-f5w6fw6q 6386 4 moyamoya moyamoya NNP cord-006870-f5w6fw6q 6386 5 as as IN cord-006870-f5w6fw6q 6386 6 the the DT cord-006870-f5w6fw6q 6386 7 causative causative JJ cord-006870-f5w6fw6q 6386 8 agent agent NN cord-006870-f5w6fw6q 6386 9 in in IN cord-006870-f5w6fw6q 6386 10 progressive progressive JJ cord-006870-f5w6fw6q 6386 11 vasculopathy vasculopathy NNP cord-006870-f5w6fw6q 6386 12 likely likely RB cord-006870-f5w6fw6q 6386 13 masqueraded masquerade VBN cord-006870-f5w6fw6q 6386 14 by by IN cord-006870-f5w6fw6q 6386 15 pituitary pituitary JJ cord-006870-f5w6fw6q 6386 16 apoplexy apoplexy NN cord-006870-f5w6fw6q 6386 17 and and CC cord-006870-f5w6fw6q 6386 18 concomitant concomitant JJ cord-006870-f5w6fw6q 6386 19 vasospasm vasospasm NN cord-006870-f5w6fw6q 6386 20 . . . cord-006870-f5w6fw6q 6387 1 Moyamoya Moyamoya NNP cord-006870-f5w6fw6q 6387 2 is be VBZ cord-006870-f5w6fw6q 6387 3 an an DT cord-006870-f5w6fw6q 6387 4 important important JJ cord-006870-f5w6fw6q 6387 5 diagnosis diagnosis NN cord-006870-f5w6fw6q 6387 6 to to TO cord-006870-f5w6fw6q 6387 7 consider consider VB cord-006870-f5w6fw6q 6387 8 in in IN cord-006870-f5w6fw6q 6387 9 patients patient NNS cord-006870-f5w6fw6q 6387 10 with with IN cord-006870-f5w6fw6q 6387 11 a a DT cord-006870-f5w6fw6q 6387 12 fulminant fulminant JJ cord-006870-f5w6fw6q 6387 13 vasculopathy vasculopathy NN cord-006870-f5w6fw6q 6387 14 refractory refractory JJ cord-006870-f5w6fw6q 6387 15 to to IN cord-006870-f5w6fw6q 6387 16 traditional traditional JJ cord-006870-f5w6fw6q 6387 17 treatment treatment NN cord-006870-f5w6fw6q 6387 18 of of IN cord-006870-f5w6fw6q 6387 19 vasospasm vasospasm NN cord-006870-f5w6fw6q 6387 20 . . . cord-006870-f5w6fw6q 6388 1 Visualization visualization NN cord-006870-f5w6fw6q 6388 2 of of IN cord-006870-f5w6fw6q 6388 3 intracranial intracranial JJ cord-006870-f5w6fw6q 6388 4 structures structure NNS cord-006870-f5w6fw6q 6388 5 by by IN cord-006870-f5w6fw6q 6388 6 ultrasound ultrasound NN cord-006870-f5w6fw6q 6388 7 in in IN cord-006870-f5w6fw6q 6388 8 adults adult NNS cord-006870-f5w6fw6q 6388 9 is be VBZ cord-006870-f5w6fw6q 6388 10 limited limit VBN cord-006870-f5w6fw6q 6388 11 by by IN cord-006870-f5w6fw6q 6388 12 the the DT cord-006870-f5w6fw6q 6388 13 presence presence NN cord-006870-f5w6fw6q 6388 14 of of IN cord-006870-f5w6fw6q 6388 15 skull skull NN cord-006870-f5w6fw6q 6388 16 , , , cord-006870-f5w6fw6q 6388 17 though though IN cord-006870-f5w6fw6q 6388 18 ultrasound ultrasound NN cord-006870-f5w6fw6q 6388 19 imaging imaging NN cord-006870-f5w6fw6q 6388 20 can can MD cord-006870-f5w6fw6q 6388 21 occur occur VB cord-006870-f5w6fw6q 6388 22 through through IN cord-006870-f5w6fw6q 6388 23 temporal temporal JJ cord-006870-f5w6fw6q 6388 24 windows window NNS cord-006870-f5w6fw6q 6388 25 . . . cord-006870-f5w6fw6q 6389 1 Point point NN cord-006870-f5w6fw6q 6389 2 of of IN cord-006870-f5w6fw6q 6389 3 care care NN cord-006870-f5w6fw6q 6389 4 ultrasound ultrasound NN cord-006870-f5w6fw6q 6389 5 allows allow VBZ cord-006870-f5w6fw6q 6389 6 assessment assessment NN cord-006870-f5w6fw6q 6389 7 of of IN cord-006870-f5w6fw6q 6389 8 midline midline JJ cord-006870-f5w6fw6q 6389 9 shift shift NN cord-006870-f5w6fw6q 6389 10 , , , cord-006870-f5w6fw6q 6389 11 brainstem brainstem NN cord-006870-f5w6fw6q 6389 12 , , , cord-006870-f5w6fw6q 6389 13 and and CC cord-006870-f5w6fw6q 6389 14 ventricles ventricle NNS cord-006870-f5w6fw6q 6389 15 . . . cord-006870-f5w6fw6q 6390 1 Doppler Doppler NNP cord-006870-f5w6fw6q 6390 2 allows allow VBZ cord-006870-f5w6fw6q 6390 3 visualization visualization NN cord-006870-f5w6fw6q 6390 4 of of IN cord-006870-f5w6fw6q 6390 5 cerebral cerebral JJ cord-006870-f5w6fw6q 6390 6 perfusion perfusion NN cord-006870-f5w6fw6q 6390 7 patterns pattern NNS cord-006870-f5w6fw6q 6390 8 . . . cord-006870-f5w6fw6q 6391 1 Patients patient NNS cord-006870-f5w6fw6q 6391 2 with with IN cord-006870-f5w6fw6q 6391 3 a a DT cord-006870-f5w6fw6q 6391 4 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 6391 5 have have VBP cord-006870-f5w6fw6q 6391 6 better well JJR cord-006870-f5w6fw6q 6391 7 temporal temporal JJ cord-006870-f5w6fw6q 6391 8 windows window NNS cord-006870-f5w6fw6q 6391 9 available available JJ cord-006870-f5w6fw6q 6391 10 since since IN cord-006870-f5w6fw6q 6391 11 a a DT cord-006870-f5w6fw6q 6391 12 portion portion NN cord-006870-f5w6fw6q 6391 13 of of IN cord-006870-f5w6fw6q 6391 14 their -PRON- PRP$ cord-006870-f5w6fw6q 6391 15 skull skull NN cord-006870-f5w6fw6q 6391 16 has have VBZ cord-006870-f5w6fw6q 6391 17 been be VBN cord-006870-f5w6fw6q 6391 18 removed remove VBN cord-006870-f5w6fw6q 6391 19 . . . cord-006870-f5w6fw6q 6392 1 In in IN cord-006870-f5w6fw6q 6392 2 such such JJ cord-006870-f5w6fw6q 6392 3 patients patient NNS cord-006870-f5w6fw6q 6392 4 , , , cord-006870-f5w6fw6q 6392 5 ultrasound ultrasound NN cord-006870-f5w6fw6q 6392 6 can can MD cord-006870-f5w6fw6q 6392 7 provide provide VB cord-006870-f5w6fw6q 6392 8 a a DT cord-006870-f5w6fw6q 6392 9 non non JJ cord-006870-f5w6fw6q 6392 10 - - JJ cord-006870-f5w6fw6q 6392 11 invasive invasive JJ cord-006870-f5w6fw6q 6392 12 method method NN cord-006870-f5w6fw6q 6392 13 to to TO cord-006870-f5w6fw6q 6392 14 serially serially RB cord-006870-f5w6fw6q 6392 15 assess assess VB cord-006870-f5w6fw6q 6392 16 midline midline JJ cord-006870-f5w6fw6q 6392 17 shift shift NN cord-006870-f5w6fw6q 6392 18 , , , cord-006870-f5w6fw6q 6392 19 intracranial intracranial JJ cord-006870-f5w6fw6q 6392 20 hematomas hematoma NNS cord-006870-f5w6fw6q 6392 21 , , , cord-006870-f5w6fw6q 6392 22 and and CC cord-006870-f5w6fw6q 6392 23 focal focal JJ cord-006870-f5w6fw6q 6392 24 ischemia ischemia NN cord-006870-f5w6fw6q 6392 25 at at IN cord-006870-f5w6fw6q 6392 26 the the DT cord-006870-f5w6fw6q 6392 27 bedside bedside NN cord-006870-f5w6fw6q 6392 28 . . . cord-006870-f5w6fw6q 6393 1 We -PRON- PRP cord-006870-f5w6fw6q 6393 2 present present VBP cord-006870-f5w6fw6q 6393 3 images image NNS cord-006870-f5w6fw6q 6393 4 of of IN cord-006870-f5w6fw6q 6393 5 a a DT cord-006870-f5w6fw6q 6393 6 cranial cranial JJ cord-006870-f5w6fw6q 6393 7 ultrasound ultrasound NN cord-006870-f5w6fw6q 6393 8 that that WDT cord-006870-f5w6fw6q 6393 9 shows show VBZ cord-006870-f5w6fw6q 6393 10 remarkable remarkable JJ cord-006870-f5w6fw6q 6393 11 anatomical anatomical JJ cord-006870-f5w6fw6q 6393 12 details detail NNS cord-006870-f5w6fw6q 6393 13 that that WDT cord-006870-f5w6fw6q 6393 14 correlate correlate VBP cord-006870-f5w6fw6q 6393 15 well well RB cord-006870-f5w6fw6q 6393 16 with with IN cord-006870-f5w6fw6q 6393 17 computed compute VBN cord-006870-f5w6fw6q 6393 18 tomography tomography NN cord-006870-f5w6fw6q 6393 19 ( ( -LRB- cord-006870-f5w6fw6q 6393 20 CT CT NNP cord-006870-f5w6fw6q 6393 21 ) ) -RRB- cord-006870-f5w6fw6q 6393 22 head head NN cord-006870-f5w6fw6q 6393 23 . . . cord-006870-f5w6fw6q 6394 1 A a DT cord-006870-f5w6fw6q 6394 2 74 74 CD cord-006870-f5w6fw6q 6394 3 year year NN cord-006870-f5w6fw6q 6394 4 - - HYPH cord-006870-f5w6fw6q 6394 5 old old JJ cord-006870-f5w6fw6q 6394 6 male male NN cord-006870-f5w6fw6q 6394 7 presented present VBN cord-006870-f5w6fw6q 6394 8 with with IN cord-006870-f5w6fw6q 6394 9 right right RB cord-006870-f5w6fw6q 6394 10 - - HYPH cord-006870-f5w6fw6q 6394 11 sided sided JJ cord-006870-f5w6fw6q 6394 12 weakness weakness NN cord-006870-f5w6fw6q 6394 13 and and CC cord-006870-f5w6fw6q 6394 14 confusion confusion NN cord-006870-f5w6fw6q 6394 15 and and CC cord-006870-f5w6fw6q 6394 16 was be VBD cord-006870-f5w6fw6q 6394 17 found find VBN cord-006870-f5w6fw6q 6394 18 to to TO cord-006870-f5w6fw6q 6394 19 have have VB cord-006870-f5w6fw6q 6394 20 a a DT cord-006870-f5w6fw6q 6394 21 left left JJ cord-006870-f5w6fw6q 6394 22 parietal parietal JJ cord-006870-f5w6fw6q 6394 23 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 6394 24 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6394 25 with with IN cord-006870-f5w6fw6q 6394 26 cerebral cerebral JJ cord-006870-f5w6fw6q 6394 27 edema edema NN cord-006870-f5w6fw6q 6394 28 and and CC cord-006870-f5w6fw6q 6394 29 left leave VBN cord-006870-f5w6fw6q 6394 30 - - HYPH cord-006870-f5w6fw6q 6394 31 to to IN cord-006870-f5w6fw6q 6394 32 - - HYPH cord-006870-f5w6fw6q 6394 33 right right JJ cord-006870-f5w6fw6q 6394 34 midline midline JJ cord-006870-f5w6fw6q 6394 35 shift shift NN cord-006870-f5w6fw6q 6394 36 on on IN cord-006870-f5w6fw6q 6394 37 CT CT NNP cord-006870-f5w6fw6q 6394 38 head head NN cord-006870-f5w6fw6q 6394 39 . . . cord-006870-f5w6fw6q 6395 1 Increase increase VB cord-006870-f5w6fw6q 6395 2 in in IN cord-006870-f5w6fw6q 6395 3 cerebral cerebral JJ cord-006870-f5w6fw6q 6395 4 edema edema NN cord-006870-f5w6fw6q 6395 5 and and CC cord-006870-f5w6fw6q 6395 6 expansion expansion NN cord-006870-f5w6fw6q 6395 7 of of IN cord-006870-f5w6fw6q 6395 8 the the DT cord-006870-f5w6fw6q 6395 9 hematoma hematoma NN cord-006870-f5w6fw6q 6395 10 caused cause VBD cord-006870-f5w6fw6q 6395 11 clinical clinical JJ cord-006870-f5w6fw6q 6395 12 neurological neurological JJ cord-006870-f5w6fw6q 6395 13 decline decline NN cord-006870-f5w6fw6q 6395 14 necessitating necessitate VBG cord-006870-f5w6fw6q 6395 15 a a DT cord-006870-f5w6fw6q 6395 16 left left JJ cord-006870-f5w6fw6q 6395 17 - - HYPH cord-006870-f5w6fw6q 6395 18 sided sided JJ cord-006870-f5w6fw6q 6395 19 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 6395 20 with with IN cord-006870-f5w6fw6q 6395 21 clot clot NN cord-006870-f5w6fw6q 6395 22 evacuation evacuation NN cord-006870-f5w6fw6q 6395 23 . . . cord-006870-f5w6fw6q 6396 1 A a DT cord-006870-f5w6fw6q 6396 2 cranial cranial JJ cord-006870-f5w6fw6q 6396 3 ultrasound ultrasound NN cord-006870-f5w6fw6q 6396 4 was be VBD cord-006870-f5w6fw6q 6396 5 performed perform VBN cord-006870-f5w6fw6q 6396 6 two two CD cord-006870-f5w6fw6q 6396 7 days day NNS cord-006870-f5w6fw6q 6396 8 after after IN cord-006870-f5w6fw6q 6396 9 surgery surgery NN cord-006870-f5w6fw6q 6396 10 to to TO cord-006870-f5w6fw6q 6396 11 assess assess VB cord-006870-f5w6fw6q 6396 12 for for IN cord-006870-f5w6fw6q 6396 13 progression progression NN cord-006870-f5w6fw6q 6396 14 of of IN cord-006870-f5w6fw6q 6396 15 cerebral cerebral JJ cord-006870-f5w6fw6q 6396 16 edema edema NN cord-006870-f5w6fw6q 6396 17 and and CC cord-006870-f5w6fw6q 6396 18 intracranial intracranial JJ cord-006870-f5w6fw6q 6396 19 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6396 20 . . . cord-006870-f5w6fw6q 6397 1 A a DT cord-006870-f5w6fw6q 6397 2 transtemporal transtemporal JJ cord-006870-f5w6fw6q 6397 3 approach approach NN cord-006870-f5w6fw6q 6397 4 in in IN cord-006870-f5w6fw6q 6397 5 axial axial JJ cord-006870-f5w6fw6q 6397 6 plane plane NN cord-006870-f5w6fw6q 6397 7 was be VBD cord-006870-f5w6fw6q 6397 8 used use VBN cord-006870-f5w6fw6q 6397 9 to to TO cord-006870-f5w6fw6q 6397 10 visualize visualize VB cord-006870-f5w6fw6q 6397 11 intracranial intracranial JJ cord-006870-f5w6fw6q 6397 12 structures structure NNS cord-006870-f5w6fw6q 6397 13 through through IN cord-006870-f5w6fw6q 6397 14 the the DT cord-006870-f5w6fw6q 6397 15 craniectomy craniectomy JJ cord-006870-f5w6fw6q 6397 16 window window NN cord-006870-f5w6fw6q 6397 17 . . . cord-006870-f5w6fw6q 6398 1 Physiological physiological JJ cord-006870-f5w6fw6q 6398 2 structures structure NNS cord-006870-f5w6fw6q 6398 3 like like IN cord-006870-f5w6fw6q 6398 4 the the DT cord-006870-f5w6fw6q 6398 5 falx falx NNP cord-006870-f5w6fw6q 6398 6 cerebri cerebri NNP cord-006870-f5w6fw6q 6398 7 , , , cord-006870-f5w6fw6q 6398 8 lateral lateral JJ cord-006870-f5w6fw6q 6398 9 ventricles ventricle NNS cord-006870-f5w6fw6q 6398 10 , , , cord-006870-f5w6fw6q 6398 11 midbrain midbrain NN cord-006870-f5w6fw6q 6398 12 , , , cord-006870-f5w6fw6q 6398 13 mammillary mammillary JJ cord-006870-f5w6fw6q 6398 14 bodies body NNS cord-006870-f5w6fw6q 6398 15 , , , cord-006870-f5w6fw6q 6398 16 choroid choroid NN cord-006870-f5w6fw6q 6398 17 plexus plexus NN cord-006870-f5w6fw6q 6398 18 , , , cord-006870-f5w6fw6q 6398 19 splenium splenium NNP cord-006870-f5w6fw6q 6398 20 of of IN cord-006870-f5w6fw6q 6398 21 corpus corpus NNP cord-006870-f5w6fw6q 6398 22 callosum callosum NNP cord-006870-f5w6fw6q 6398 23 , , , cord-006870-f5w6fw6q 6398 24 thalami thalami NNP cord-006870-f5w6fw6q 6398 25 , , , cord-006870-f5w6fw6q 6398 26 and and CC cord-006870-f5w6fw6q 6398 27 circle circle NN cord-006870-f5w6fw6q 6398 28 of of IN cord-006870-f5w6fw6q 6398 29 Willis Willis NNP cord-006870-f5w6fw6q 6398 30 were be VBD cord-006870-f5w6fw6q 6398 31 visualized visualize VBN cord-006870-f5w6fw6q 6398 32 with with IN cord-006870-f5w6fw6q 6398 33 incredible incredible JJ cord-006870-f5w6fw6q 6398 34 anatomical anatomical JJ cord-006870-f5w6fw6q 6398 35 detail detail NN cord-006870-f5w6fw6q 6398 36 . . . cord-006870-f5w6fw6q 6399 1 Pathology pathology NN cord-006870-f5w6fw6q 6399 2 such such JJ cord-006870-f5w6fw6q 6399 3 as as IN cord-006870-f5w6fw6q 6399 4 intracranial intracranial JJ cord-006870-f5w6fw6q 6399 5 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6399 6 , , , cord-006870-f5w6fw6q 6399 7 focal focal JJ cord-006870-f5w6fw6q 6399 8 ischemic ischemic JJ cord-006870-f5w6fw6q 6399 9 areas area NNS cord-006870-f5w6fw6q 6399 10 , , , cord-006870-f5w6fw6q 6399 11 vasogenic vasogenic NN cord-006870-f5w6fw6q 6399 12 edema edema NN cord-006870-f5w6fw6q 6399 13 as as RB cord-006870-f5w6fw6q 6399 14 well well RB cord-006870-f5w6fw6q 6399 15 as as IN cord-006870-f5w6fw6q 6399 16 encephalomalacia encephalomalacia NNS cord-006870-f5w6fw6q 6399 17 were be VBD cord-006870-f5w6fw6q 6399 18 identified identify VBN cord-006870-f5w6fw6q 6399 19 with with IN cord-006870-f5w6fw6q 6399 20 close close JJ cord-006870-f5w6fw6q 6399 21 correlation correlation NN cord-006870-f5w6fw6q 6399 22 to to IN cord-006870-f5w6fw6q 6399 23 the the DT cord-006870-f5w6fw6q 6399 24 noncontrast noncontrast JJ cord-006870-f5w6fw6q 6399 25 head head NN cord-006870-f5w6fw6q 6399 26 CT CT NNP cord-006870-f5w6fw6q 6399 27 . . . cord-006870-f5w6fw6q 6400 1 The the DT cord-006870-f5w6fw6q 6400 2 patient patient NN cord-006870-f5w6fw6q 6400 3 is be VBZ cord-006870-f5w6fw6q 6400 4 currently currently RB cord-006870-f5w6fw6q 6400 5 recovering recover VBG cord-006870-f5w6fw6q 6400 6 in in IN cord-006870-f5w6fw6q 6400 7 the the DT cord-006870-f5w6fw6q 6400 8 neurocritical neurocritical NNP cord-006870-f5w6fw6q 6400 9 care care NNP cord-006870-f5w6fw6q 6400 10 unit unit NN cord-006870-f5w6fw6q 6400 11 with with IN cord-006870-f5w6fw6q 6400 12 supportive supportive JJ cord-006870-f5w6fw6q 6400 13 care care NN cord-006870-f5w6fw6q 6400 14 . . . cord-006870-f5w6fw6q 6401 1 Cranial cranial JJ cord-006870-f5w6fw6q 6401 2 ultrasound ultrasound NN cord-006870-f5w6fw6q 6401 3 has have VBZ cord-006870-f5w6fw6q 6401 4 potential potential JJ cord-006870-f5w6fw6q 6401 5 applications application NNS cord-006870-f5w6fw6q 6401 6 in in IN cord-006870-f5w6fw6q 6401 7 point point NN cord-006870-f5w6fw6q 6401 8 of of IN cord-006870-f5w6fw6q 6401 9 care care NN cord-006870-f5w6fw6q 6401 10 assessment assessment NN cord-006870-f5w6fw6q 6401 11 of of IN cord-006870-f5w6fw6q 6401 12 intracranial intracranial JJ cord-006870-f5w6fw6q 6401 13 pathology pathology NN cord-006870-f5w6fw6q 6401 14 in in IN cord-006870-f5w6fw6q 6401 15 neurocritical neurocritical NNP cord-006870-f5w6fw6q 6401 16 care care NN cord-006870-f5w6fw6q 6401 17 patients patient NNS cord-006870-f5w6fw6q 6401 18 . . . cord-006870-f5w6fw6q 6402 1 This this DT cord-006870-f5w6fw6q 6402 2 application application NN cord-006870-f5w6fw6q 6402 3 has have VBZ cord-006870-f5w6fw6q 6402 4 promising promise VBG cord-006870-f5w6fw6q 6402 5 use use NN cord-006870-f5w6fw6q 6402 6 in in IN cord-006870-f5w6fw6q 6402 7 directing direct VBG cord-006870-f5w6fw6q 6402 8 therapy therapy NN cord-006870-f5w6fw6q 6402 9 in in IN cord-006870-f5w6fw6q 6402 10 patients patient NNS cord-006870-f5w6fw6q 6402 11 who who WP cord-006870-f5w6fw6q 6402 12 are be VBP cord-006870-f5w6fw6q 6402 13 otherwise otherwise RB cord-006870-f5w6fw6q 6402 14 unstable unstable JJ cord-006870-f5w6fw6q 6402 15 for for IN cord-006870-f5w6fw6q 6402 16 transport transport NN cord-006870-f5w6fw6q 6402 17 or or CC cord-006870-f5w6fw6q 6402 18 are be VBP cord-006870-f5w6fw6q 6402 19 unable unable JJ cord-006870-f5w6fw6q 6402 20 to to TO cord-006870-f5w6fw6q 6402 21 undergo undergo VB cord-006870-f5w6fw6q 6402 22 neuroimaging neuroimage VBG cord-006870-f5w6fw6q 6402 23 secondary secondary JJ cord-006870-f5w6fw6q 6402 24 to to IN cord-006870-f5w6fw6q 6402 25 positioning position VBG cord-006870-f5w6fw6q 6402 26 needed need VBN cord-006870-f5w6fw6q 6402 27 for for IN cord-006870-f5w6fw6q 6402 28 management management NN cord-006870-f5w6fw6q 6402 29 of of IN cord-006870-f5w6fw6q 6402 30 cerebral cerebral JJ cord-006870-f5w6fw6q 6402 31 edema edema NN cord-006870-f5w6fw6q 6402 32 . . . cord-006870-f5w6fw6q 6403 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 6403 2 mucormycosis mucormycosis NN cord-006870-f5w6fw6q 6403 3 is be VBZ cord-006870-f5w6fw6q 6403 4 a a DT cord-006870-f5w6fw6q 6403 5 rare rare JJ cord-006870-f5w6fw6q 6403 6 infection infection NN cord-006870-f5w6fw6q 6403 7 caused cause VBN cord-006870-f5w6fw6q 6403 8 by by IN cord-006870-f5w6fw6q 6403 9 fungi fungus NNS cord-006870-f5w6fw6q 6403 10 found find VBN cord-006870-f5w6fw6q 6403 11 in in IN cord-006870-f5w6fw6q 6403 12 soil soil NN cord-006870-f5w6fw6q 6403 13 and and CC cord-006870-f5w6fw6q 6403 14 decaying decay VBG cord-006870-f5w6fw6q 6403 15 vegetation vegetation NN cord-006870-f5w6fw6q 6403 16 . . . cord-006870-f5w6fw6q 6404 1 The the DT cord-006870-f5w6fw6q 6404 2 rhino rhino NN cord-006870-f5w6fw6q 6404 3 - - HYPH cord-006870-f5w6fw6q 6404 4 orbital orbital JJ cord-006870-f5w6fw6q 6404 5 - - HYPH cord-006870-f5w6fw6q 6404 6 cerebral cerebral JJ cord-006870-f5w6fw6q 6404 7 type type NN cord-006870-f5w6fw6q 6404 8 is be VBZ cord-006870-f5w6fw6q 6404 9 classically classically RB cord-006870-f5w6fw6q 6404 10 associated associate VBN cord-006870-f5w6fw6q 6404 11 with with IN cord-006870-f5w6fw6q 6404 12 AIDS AIDS NNP cord-006870-f5w6fw6q 6404 13 , , , cord-006870-f5w6fw6q 6404 14 diabetes diabetes NN cord-006870-f5w6fw6q 6404 15 , , , cord-006870-f5w6fw6q 6404 16 malignancy malignancy NN cord-006870-f5w6fw6q 6404 17 and and CC cord-006870-f5w6fw6q 6404 18 immunosuppression immunosuppression NN cord-006870-f5w6fw6q 6404 19 . . . cord-006870-f5w6fw6q 6405 1 We -PRON- PRP cord-006870-f5w6fw6q 6405 2 observed observe VBD cord-006870-f5w6fw6q 6405 3 a a DT cord-006870-f5w6fw6q 6405 4 series series NN cord-006870-f5w6fw6q 6405 5 of of IN cord-006870-f5w6fw6q 6405 6 young young JJ cord-006870-f5w6fw6q 6405 7 immunocompetent immunocompetent JJ cord-006870-f5w6fw6q 6405 8 patients patient NNS cord-006870-f5w6fw6q 6405 9 who who WP cord-006870-f5w6fw6q 6405 10 presented present VBD cord-006870-f5w6fw6q 6405 11 with with IN cord-006870-f5w6fw6q 6405 12 a a DT cord-006870-f5w6fw6q 6405 13 fulminant fulminant JJ cord-006870-f5w6fw6q 6405 14 form form NN cord-006870-f5w6fw6q 6405 15 of of IN cord-006870-f5w6fw6q 6405 16 isolated isolate VBN cord-006870-f5w6fw6q 6405 17 cerebral cerebral JJ cord-006870-f5w6fw6q 6405 18 mucor mucor NN cord-006870-f5w6fw6q 6405 19 associated associate VBN cord-006870-f5w6fw6q 6405 20 with with IN cord-006870-f5w6fw6q 6405 21 severe severe JJ cord-006870-f5w6fw6q 6405 22 meningoencephalitis meningoencephalitis NN cord-006870-f5w6fw6q 6405 23 , , , cord-006870-f5w6fw6q 6405 24 parenchymal parenchymal JJ cord-006870-f5w6fw6q 6405 25 necrosis necrosis NN cord-006870-f5w6fw6q 6405 26 and and CC cord-006870-f5w6fw6q 6405 27 symptomatic symptomatic JJ cord-006870-f5w6fw6q 6405 28 cerebral cerebral JJ cord-006870-f5w6fw6q 6405 29 edema edema NN cord-006870-f5w6fw6q 6405 30 . . . cord-006870-f5w6fw6q 6406 1 Six six CD cord-006870-f5w6fw6q 6406 2 patients patient NNS cord-006870-f5w6fw6q 6406 3 with with IN cord-006870-f5w6fw6q 6406 4 histopathological histopathological JJ cord-006870-f5w6fw6q 6406 5 diagnosis diagnosis NN cord-006870-f5w6fw6q 6406 6 of of IN cord-006870-f5w6fw6q 6406 7 CNS CNS NNP cord-006870-f5w6fw6q 6406 8 mucormycosis mucormycosis NNP cord-006870-f5w6fw6q 6406 9 admitted admit VBN cord-006870-f5w6fw6q 6406 10 to to IN cord-006870-f5w6fw6q 6406 11 the the DT cord-006870-f5w6fw6q 6406 12 University University NNP cord-006870-f5w6fw6q 6406 13 of of IN cord-006870-f5w6fw6q 6406 14 Cincinnati Cincinnati NNP cord-006870-f5w6fw6q 6406 15 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 6406 16 Care Care NNP cord-006870-f5w6fw6q 6406 17 Unit Unit NNP cord-006870-f5w6fw6q 6406 18 between between IN cord-006870-f5w6fw6q 6406 19 2008 2008 CD cord-006870-f5w6fw6q 6406 20 and and CC cord-006870-f5w6fw6q 6406 21 2017 2017 CD cord-006870-f5w6fw6q 6406 22 are be VBP cord-006870-f5w6fw6q 6406 23 presented present VBN cord-006870-f5w6fw6q 6406 24 . . . cord-006870-f5w6fw6q 6407 1 Patient patient JJ cord-006870-f5w6fw6q 6407 2 ages age NNS cord-006870-f5w6fw6q 6407 3 ranged range VBD cord-006870-f5w6fw6q 6407 4 from from IN cord-006870-f5w6fw6q 6407 5 22 22 CD cord-006870-f5w6fw6q 6407 6 - - SYM cord-006870-f5w6fw6q 6407 7 45 45 CD cord-006870-f5w6fw6q 6407 8 ( ( -LRB- cord-006870-f5w6fw6q 6407 9 median median NN cord-006870-f5w6fw6q 6407 10 27 27 CD cord-006870-f5w6fw6q 6407 11 ) ) -RRB- cord-006870-f5w6fw6q 6407 12 . . . cord-006870-f5w6fw6q 6408 1 None none NN cord-006870-f5w6fw6q 6408 2 had have VBD cord-006870-f5w6fw6q 6408 3 diabetes diabete NNS cord-006870-f5w6fw6q 6408 4 or or CC cord-006870-f5w6fw6q 6408 5 HIV HIV NNP cord-006870-f5w6fw6q 6408 6 . . . cord-006870-f5w6fw6q 6409 1 Drug drug NN cord-006870-f5w6fw6q 6409 2 use use NN cord-006870-f5w6fw6q 6409 3 ( ( -LRB- cord-006870-f5w6fw6q 6409 4 intravenous intravenous JJ cord-006870-f5w6fw6q 6409 5 and and CC cord-006870-f5w6fw6q 6409 6 intranasal intranasal NN cord-006870-f5w6fw6q 6409 7 ) ) -RRB- cord-006870-f5w6fw6q 6409 8 was be VBD cord-006870-f5w6fw6q 6409 9 confirmed confirm VBN cord-006870-f5w6fw6q 6409 10 in in IN cord-006870-f5w6fw6q 6409 11 4 4 CD cord-006870-f5w6fw6q 6409 12 patients patient NNS cord-006870-f5w6fw6q 6409 13 . . . cord-006870-f5w6fw6q 6410 1 They -PRON- PRP cord-006870-f5w6fw6q 6410 2 presented present VBD cord-006870-f5w6fw6q 6410 3 with with IN cord-006870-f5w6fw6q 6410 4 altered altered JJ cord-006870-f5w6fw6q 6410 5 mental mental JJ cord-006870-f5w6fw6q 6410 6 status status NN cord-006870-f5w6fw6q 6410 7 ( ( -LRB- cord-006870-f5w6fw6q 6410 8 2 2 CD cord-006870-f5w6fw6q 6410 9 ) ) -RRB- cord-006870-f5w6fw6q 6410 10 and and CC cord-006870-f5w6fw6q 6410 11 focal focal JJ cord-006870-f5w6fw6q 6410 12 neurologic neurologic JJ cord-006870-f5w6fw6q 6410 13 deficits deficit NNS cord-006870-f5w6fw6q 6410 14 ( ( -LRB- cord-006870-f5w6fw6q 6410 15 4 4 CD cord-006870-f5w6fw6q 6410 16 ) ) -RRB- cord-006870-f5w6fw6q 6410 17 . . . cord-006870-f5w6fw6q 6411 1 Four four CD cord-006870-f5w6fw6q 6411 2 patients patient NNS cord-006870-f5w6fw6q 6411 3 presented present VBN cord-006870-f5w6fw6q 6411 4 with with IN cord-006870-f5w6fw6q 6411 5 fever fever NN cord-006870-f5w6fw6q 6411 6 and and CC cord-006870-f5w6fw6q 6411 7 leukocytosis leukocytosis NN cord-006870-f5w6fw6q 6411 8 . . . cord-006870-f5w6fw6q 6412 1 MRI MRI NNP cord-006870-f5w6fw6q 6412 2 revealed reveal VBD cord-006870-f5w6fw6q 6412 3 lesions lesion NNS cord-006870-f5w6fw6q 6412 4 in in IN cord-006870-f5w6fw6q 6412 5 the the DT cord-006870-f5w6fw6q 6412 6 basal basal NN cord-006870-f5w6fw6q 6412 7 ganglia ganglion NNS cord-006870-f5w6fw6q 6412 8 ( ( -LRB- cord-006870-f5w6fw6q 6412 9 5 5 CD cord-006870-f5w6fw6q 6412 10 ) ) -RRB- cord-006870-f5w6fw6q 6412 11 or or CC cord-006870-f5w6fw6q 6412 12 cerebellum cerebellum NN cord-006870-f5w6fw6q 6412 13 ( ( -LRB- cord-006870-f5w6fw6q 6412 14 1 1 CD cord-006870-f5w6fw6q 6412 15 ) ) -RRB- cord-006870-f5w6fw6q 6412 16 which which WDT cord-006870-f5w6fw6q 6412 17 were be VBD cord-006870-f5w6fw6q 6412 18 characterized characterize VBN cord-006870-f5w6fw6q 6412 19 by by IN cord-006870-f5w6fw6q 6412 20 T2 T2 NNP cord-006870-f5w6fw6q 6412 21 hyperintensities hyperintensitie NNS cord-006870-f5w6fw6q 6412 22 with with IN cord-006870-f5w6fw6q 6412 23 patchy patchy JJ cord-006870-f5w6fw6q 6412 24 restriction restriction NN cord-006870-f5w6fw6q 6412 25 and and CC cord-006870-f5w6fw6q 6412 26 susceptibility susceptibility NN cord-006870-f5w6fw6q 6412 27 signal signal NN cord-006870-f5w6fw6q 6412 28 . . . cord-006870-f5w6fw6q 6413 1 Contrast contrast NN cord-006870-f5w6fw6q 6413 2 enhancement enhancement NN cord-006870-f5w6fw6q 6413 3 was be VBD cord-006870-f5w6fw6q 6413 4 present present JJ cord-006870-f5w6fw6q 6413 5 in in IN cord-006870-f5w6fw6q 6413 6 5 5 CD cord-006870-f5w6fw6q 6413 7 patients patient NNS cord-006870-f5w6fw6q 6413 8 . . . cord-006870-f5w6fw6q 6414 1 Mass mass JJ cord-006870-f5w6fw6q 6414 2 effect effect NN cord-006870-f5w6fw6q 6414 3 ( ( -LRB- cord-006870-f5w6fw6q 6414 4 6 6 CD cord-006870-f5w6fw6q 6414 5 ) ) -RRB- cord-006870-f5w6fw6q 6414 6 and and CC cord-006870-f5w6fw6q 6414 7 midline midline JJ cord-006870-f5w6fw6q 6414 8 shift shift NN cord-006870-f5w6fw6q 6414 9 ( ( -LRB- cord-006870-f5w6fw6q 6414 10 4 4 CD cord-006870-f5w6fw6q 6414 11 ) ) -RRB- cord-006870-f5w6fw6q 6414 12 were be VBD cord-006870-f5w6fw6q 6414 13 prominent prominent JJ cord-006870-f5w6fw6q 6414 14 . . . cord-006870-f5w6fw6q 6415 1 Mechanical mechanical JJ cord-006870-f5w6fw6q 6415 2 ventilation ventilation NN cord-006870-f5w6fw6q 6415 3 was be VBD cord-006870-f5w6fw6q 6415 4 required require VBN cord-006870-f5w6fw6q 6415 5 in in IN cord-006870-f5w6fw6q 6415 6 four four CD cord-006870-f5w6fw6q 6415 7 patients patient NNS cord-006870-f5w6fw6q 6415 8 . . . cord-006870-f5w6fw6q 6416 1 All all DT cord-006870-f5w6fw6q 6416 2 but but IN cord-006870-f5w6fw6q 6416 3 one one CD cord-006870-f5w6fw6q 6416 4 patient patient NN cord-006870-f5w6fw6q 6416 5 received receive VBD cord-006870-f5w6fw6q 6416 6 Amphotericin Amphotericin NNP cord-006870-f5w6fw6q 6416 7 B. B. NNP cord-006870-f5w6fw6q 6416 8 Three Three NNP cord-006870-f5w6fw6q 6416 9 died die VBD cord-006870-f5w6fw6q 6416 10 from from IN cord-006870-f5w6fw6q 6416 11 intractable intractable JJ cord-006870-f5w6fw6q 6416 12 intracranial intracranial JJ cord-006870-f5w6fw6q 6416 13 pressure pressure NN cord-006870-f5w6fw6q 6416 14 ( ( -LRB- cord-006870-f5w6fw6q 6416 15 ICP ICP NNP cord-006870-f5w6fw6q 6416 16 ) ) -RRB- cord-006870-f5w6fw6q 6416 17 . . . cord-006870-f5w6fw6q 6417 1 One one CD cord-006870-f5w6fw6q 6417 2 patient patient NN cord-006870-f5w6fw6q 6417 3 eventually eventually RB cord-006870-f5w6fw6q 6417 4 gained gain VBD cord-006870-f5w6fw6q 6417 5 functional functional JJ cord-006870-f5w6fw6q 6417 6 independence independence NN cord-006870-f5w6fw6q 6417 7 , , , cord-006870-f5w6fw6q 6417 8 one one CD cord-006870-f5w6fw6q 6417 9 still still RB cord-006870-f5w6fw6q 6417 10 requires require VBZ cord-006870-f5w6fw6q 6417 11 high high JJ cord-006870-f5w6fw6q 6417 12 level level NN cord-006870-f5w6fw6q 6417 13 of of IN cord-006870-f5w6fw6q 6417 14 care care NN cord-006870-f5w6fw6q 6417 15 , , , cord-006870-f5w6fw6q 6417 16 and and CC cord-006870-f5w6fw6q 6417 17 one one CD cord-006870-f5w6fw6q 6417 18 was be VBD cord-006870-f5w6fw6q 6417 19 lost lose VBN cord-006870-f5w6fw6q 6417 20 to to TO cord-006870-f5w6fw6q 6417 21 follow follow VB cord-006870-f5w6fw6q 6417 22 - - HYPH cord-006870-f5w6fw6q 6417 23 up up NN cord-006870-f5w6fw6q 6417 24 . . . cord-006870-f5w6fw6q 6418 1 CSF CSF NNP cord-006870-f5w6fw6q 6418 2 analysis analysis NN cord-006870-f5w6fw6q 6418 3 was be VBD cord-006870-f5w6fw6q 6418 4 negative negative JJ cord-006870-f5w6fw6q 6418 5 for for IN cord-006870-f5w6fw6q 6418 6 mucor mucor NN cord-006870-f5w6fw6q 6418 7 in in IN cord-006870-f5w6fw6q 6418 8 all all DT cord-006870-f5w6fw6q 6418 9 cases case NNS cord-006870-f5w6fw6q 6418 10 . . . cord-006870-f5w6fw6q 6419 1 Fulminant Fulminant NNP cord-006870-f5w6fw6q 6419 2 Cerebral cerebral JJ cord-006870-f5w6fw6q 6419 3 mucormycosis mucormycosis NN cord-006870-f5w6fw6q 6419 4 should should MD cord-006870-f5w6fw6q 6419 5 be be VB cord-006870-f5w6fw6q 6419 6 considered consider VBN cord-006870-f5w6fw6q 6419 7 in in IN cord-006870-f5w6fw6q 6419 8 every every DT cord-006870-f5w6fw6q 6419 9 young young JJ cord-006870-f5w6fw6q 6419 10 patient patient NN cord-006870-f5w6fw6q 6419 11 presenting present VBG cord-006870-f5w6fw6q 6419 12 with with IN cord-006870-f5w6fw6q 6419 13 rapid rapid JJ cord-006870-f5w6fw6q 6419 14 onset onset NN cord-006870-f5w6fw6q 6419 15 meningo meningo NN cord-006870-f5w6fw6q 6419 16 - - : cord-006870-f5w6fw6q 6419 17 encephalitis encephalitis RB cord-006870-f5w6fw6q 6419 18 and and CC cord-006870-f5w6fw6q 6419 19 necrotized necrotize VBN cord-006870-f5w6fw6q 6419 20 cerebral cerebral JJ cord-006870-f5w6fw6q 6419 21 lesions lesion NNS cord-006870-f5w6fw6q 6419 22 , , , cord-006870-f5w6fw6q 6419 23 especially especially RB cord-006870-f5w6fw6q 6419 24 if if IN cord-006870-f5w6fw6q 6419 25 located locate VBN cord-006870-f5w6fw6q 6419 26 in in IN cord-006870-f5w6fw6q 6419 27 the the DT cord-006870-f5w6fw6q 6419 28 basal basal NN cord-006870-f5w6fw6q 6419 29 ganglia ganglion NNS cord-006870-f5w6fw6q 6419 30 . . . cord-006870-f5w6fw6q 6420 1 History history NN cord-006870-f5w6fw6q 6420 2 of of IN cord-006870-f5w6fw6q 6420 3 IVDU IVDU NNP cord-006870-f5w6fw6q 6420 4 should should MD cord-006870-f5w6fw6q 6420 5 raise raise VB cord-006870-f5w6fw6q 6420 6 further further JJ cord-006870-f5w6fw6q 6420 7 suspicion suspicion NN cord-006870-f5w6fw6q 6420 8 . . . cord-006870-f5w6fw6q 6421 1 These these DT cord-006870-f5w6fw6q 6421 2 patients patient NNS cord-006870-f5w6fw6q 6421 3 should should MD cord-006870-f5w6fw6q 6421 4 be be VB cord-006870-f5w6fw6q 6421 5 monitored monitor VBN cord-006870-f5w6fw6q 6421 6 in in IN cord-006870-f5w6fw6q 6421 7 intensive intensive JJ cord-006870-f5w6fw6q 6421 8 care care NN cord-006870-f5w6fw6q 6421 9 settings setting NNS cord-006870-f5w6fw6q 6421 10 as as IN cord-006870-f5w6fw6q 6421 11 they -PRON- PRP cord-006870-f5w6fw6q 6421 12 can can MD cord-006870-f5w6fw6q 6421 13 rapidly rapidly RB cord-006870-f5w6fw6q 6421 14 develop develop VB cord-006870-f5w6fw6q 6421 15 malignant malignant JJ cord-006870-f5w6fw6q 6421 16 cerebral cerebral JJ cord-006870-f5w6fw6q 6421 17 edema edema NN cord-006870-f5w6fw6q 6421 18 and and CC cord-006870-f5w6fw6q 6421 19 increased increase VBN cord-006870-f5w6fw6q 6421 20 ICP ICP NNP cord-006870-f5w6fw6q 6421 21 . . . cord-006870-f5w6fw6q 6422 1 Antifungal antifungal JJ cord-006870-f5w6fw6q 6422 2 therapy therapy NN cord-006870-f5w6fw6q 6422 3 should should MD cord-006870-f5w6fw6q 6422 4 be be VB cord-006870-f5w6fw6q 6422 5 initiated initiate VBN cord-006870-f5w6fw6q 6422 6 upon upon IN cord-006870-f5w6fw6q 6422 7 presentation presentation NN cord-006870-f5w6fw6q 6422 8 as as IN cord-006870-f5w6fw6q 6422 9 it -PRON- PRP cord-006870-f5w6fw6q 6422 10 has have VBZ cord-006870-f5w6fw6q 6422 11 been be VBN cord-006870-f5w6fw6q 6422 12 shown show VBN cord-006870-f5w6fw6q 6422 13 to to TO cord-006870-f5w6fw6q 6422 14 improve improve VB cord-006870-f5w6fw6q 6422 15 morbidity morbidity NN cord-006870-f5w6fw6q 6422 16 and and CC cord-006870-f5w6fw6q 6422 17 mortality mortality NN cord-006870-f5w6fw6q 6422 18 . . . cord-006870-f5w6fw6q 6423 1 The the DT cord-006870-f5w6fw6q 6423 2 incidence incidence NN cord-006870-f5w6fw6q 6423 3 of of IN cord-006870-f5w6fw6q 6423 4 acute acute JJ cord-006870-f5w6fw6q 6423 5 ischemic ischemic JJ cord-006870-f5w6fw6q 6423 6 stroke stroke NN cord-006870-f5w6fw6q 6423 7 in in IN cord-006870-f5w6fw6q 6423 8 the the DT cord-006870-f5w6fw6q 6423 9 immediate immediate JJ cord-006870-f5w6fw6q 6423 10 post post JJ cord-006870-f5w6fw6q 6423 11 - - JJ cord-006870-f5w6fw6q 6423 12 partum partum JJ cord-006870-f5w6fw6q 6423 13 period period NN cord-006870-f5w6fw6q 6423 14 ranges range VBZ cord-006870-f5w6fw6q 6423 15 between between IN cord-006870-f5w6fw6q 6423 16 4 4 CD cord-006870-f5w6fw6q 6423 17 - - SYM cord-006870-f5w6fw6q 6423 18 18 18 CD cord-006870-f5w6fw6q 6423 19 % % NN cord-006870-f5w6fw6q 6423 20 and and CC cord-006870-f5w6fw6q 6423 21 is be VBZ cord-006870-f5w6fw6q 6423 22 considered consider VBN cord-006870-f5w6fw6q 6423 23 a a DT cord-006870-f5w6fw6q 6423 24 serious serious JJ cord-006870-f5w6fw6q 6423 25 cause cause NN cord-006870-f5w6fw6q 6423 26 of of IN cord-006870-f5w6fw6q 6423 27 morbidity morbidity NN cord-006870-f5w6fw6q 6423 28 and and CC cord-006870-f5w6fw6q 6423 29 mortality mortality NN cord-006870-f5w6fw6q 6423 30 . . . cord-006870-f5w6fw6q 6424 1 Pregnant pregnant JJ cord-006870-f5w6fw6q 6424 2 or or CC cord-006870-f5w6fw6q 6424 3 postpartum postpartum NN cord-006870-f5w6fw6q 6424 4 women woman NNS cord-006870-f5w6fw6q 6424 5 are be VBP cord-006870-f5w6fw6q 6424 6 less less RBR cord-006870-f5w6fw6q 6424 7 likely likely JJ cord-006870-f5w6fw6q 6424 8 to to TO cord-006870-f5w6fw6q 6424 9 receive receive VB cord-006870-f5w6fw6q 6424 10 IV IV NNP cord-006870-f5w6fw6q 6424 11 tissue tissue NN cord-006870-f5w6fw6q 6424 12 plasminogen plasminogen NN cord-006870-f5w6fw6q 6424 13 activator activator NN cord-006870-f5w6fw6q 6424 14 ( ( -LRB- cord-006870-f5w6fw6q 6424 15 tPA tPA NNP cord-006870-f5w6fw6q 6424 16 ) ) -RRB- cord-006870-f5w6fw6q 6424 17 primarily primarily RB cord-006870-f5w6fw6q 6424 18 because because IN cord-006870-f5w6fw6q 6424 19 of of IN cord-006870-f5w6fw6q 6424 20 pregnancy pregnancy NN cord-006870-f5w6fw6q 6424 21 , , , cord-006870-f5w6fw6q 6424 22 ongoing ongoing JJ cord-006870-f5w6fw6q 6424 23 peripartum peripartum NN cord-006870-f5w6fw6q 6424 24 bleeding bleed VBG cord-006870-f5w6fw6q 6424 25 and/or and/or CC cord-006870-f5w6fw6q 6424 26 recent recent JJ cord-006870-f5w6fw6q 6424 27 delivery delivery NN cord-006870-f5w6fw6q 6424 28 . . . cord-006870-f5w6fw6q 6425 1 The the DT cord-006870-f5w6fw6q 6425 2 FDA FDA NNP cord-006870-f5w6fw6q 6425 3 classifies classify VBZ cord-006870-f5w6fw6q 6425 4 tPA tPA NNP cord-006870-f5w6fw6q 6425 5 as as IN cord-006870-f5w6fw6q 6425 6 a a DT cord-006870-f5w6fw6q 6425 7 category category NN cord-006870-f5w6fw6q 6425 8 C c NN cord-006870-f5w6fw6q 6425 9 drug drug NN cord-006870-f5w6fw6q 6425 10 and and CC cord-006870-f5w6fw6q 6425 11 current current JJ cord-006870-f5w6fw6q 6425 12 recommendations recommendation NNS cord-006870-f5w6fw6q 6425 13 consider consider VBP cord-006870-f5w6fw6q 6425 14 pregnancy pregnancy NN cord-006870-f5w6fw6q 6425 15 a a DT cord-006870-f5w6fw6q 6425 16 relative relative JJ cord-006870-f5w6fw6q 6425 17 contraindication contraindication NN cord-006870-f5w6fw6q 6425 18 for for IN cord-006870-f5w6fw6q 6425 19 receiving receive VBG cord-006870-f5w6fw6q 6425 20 tPA tPA NNP cord-006870-f5w6fw6q 6425 21 . . . cord-006870-f5w6fw6q 6426 1 We -PRON- PRP cord-006870-f5w6fw6q 6426 2 present present VBP cord-006870-f5w6fw6q 6426 3 two two CD cord-006870-f5w6fw6q 6426 4 cases case NNS cord-006870-f5w6fw6q 6426 5 of of IN cord-006870-f5w6fw6q 6426 6 peripartum peripartum NN cord-006870-f5w6fw6q 6426 7 ischemic ischemic JJ cord-006870-f5w6fw6q 6426 8 strokes stroke NNS cord-006870-f5w6fw6q 6426 9 with with IN cord-006870-f5w6fw6q 6426 10 varying vary VBG cord-006870-f5w6fw6q 6426 11 ischemic ischemic JJ cord-006870-f5w6fw6q 6426 12 stroke stroke NN cord-006870-f5w6fw6q 6426 13 time time NN cord-006870-f5w6fw6q 6426 14 windows window NNS cord-006870-f5w6fw6q 6426 15 requiring require VBG cord-006870-f5w6fw6q 6426 16 aggressive aggressive JJ cord-006870-f5w6fw6q 6426 17 revascularization revascularization NN cord-006870-f5w6fw6q 6426 18 therapy therapy NN cord-006870-f5w6fw6q 6426 19 ( ( -LRB- cord-006870-f5w6fw6q 6426 20 endovascular endovascular JJ cord-006870-f5w6fw6q 6426 21 and and CC cord-006870-f5w6fw6q 6426 22 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 6426 23 ) ) -RRB- cord-006870-f5w6fw6q 6426 24 . . . cord-006870-f5w6fw6q 6427 1 A a DT cord-006870-f5w6fw6q 6427 2 32Y 32y CD cord-006870-f5w6fw6q 6427 3 G2P2 G2P2 NNP cord-006870-f5w6fw6q 6427 4 presented present VBD cord-006870-f5w6fw6q 6427 5 to to IN cord-006870-f5w6fw6q 6427 6 an an DT cord-006870-f5w6fw6q 6427 7 outside outside JJ cord-006870-f5w6fw6q 6427 8 hospital hospital NN cord-006870-f5w6fw6q 6427 9 12 12 CD cord-006870-f5w6fw6q 6427 10 days day NNS cord-006870-f5w6fw6q 6427 11 post post NN cord-006870-f5w6fw6q 6427 12 - - JJ cord-006870-f5w6fw6q 6427 13 partum partum JJ cord-006870-f5w6fw6q 6427 14 with with IN cord-006870-f5w6fw6q 6427 15 new new JJ cord-006870-f5w6fw6q 6427 16 onset onset NN cord-006870-f5w6fw6q 6427 17 of of IN cord-006870-f5w6fw6q 6427 18 facial facial JJ cord-006870-f5w6fw6q 6427 19 droop droop NN cord-006870-f5w6fw6q 6427 20 and and CC cord-006870-f5w6fw6q 6427 21 left leave VBD cord-006870-f5w6fw6q 6427 22 upper upper JJ cord-006870-f5w6fw6q 6427 23 extremity extremity NN cord-006870-f5w6fw6q 6427 24 weakness weakness NN cord-006870-f5w6fw6q 6427 25 ( ( -LRB- cord-006870-f5w6fw6q 6427 26 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6427 27 6 6 CD cord-006870-f5w6fw6q 6427 28 ) ) -RRB- cord-006870-f5w6fw6q 6427 29 . . . cord-006870-f5w6fw6q 6428 1 Imaging imaging NN cord-006870-f5w6fw6q 6428 2 showed show VBD cord-006870-f5w6fw6q 6428 3 right right JJ cord-006870-f5w6fw6q 6428 4 M1 M1 NNP cord-006870-f5w6fw6q 6428 5 cutoff cutoff NN cord-006870-f5w6fw6q 6428 6 and and CC cord-006870-f5w6fw6q 6428 7 occlusion occlusion NN cord-006870-f5w6fw6q 6428 8 of of IN cord-006870-f5w6fw6q 6428 9 several several JJ cord-006870-f5w6fw6q 6428 10 M2 M2 NNP cord-006870-f5w6fw6q 6428 11 branches branch NNS cord-006870-f5w6fw6q 6428 12 . . . cord-006870-f5w6fw6q 6429 1 The the DT cord-006870-f5w6fw6q 6429 2 patient patient NN cord-006870-f5w6fw6q 6429 3 was be VBD cord-006870-f5w6fw6q 6429 4 not not RB cord-006870-f5w6fw6q 6429 5 a a DT cord-006870-f5w6fw6q 6429 6 candidate candidate NN cord-006870-f5w6fw6q 6429 7 for for IN cord-006870-f5w6fw6q 6429 8 tPA tPA NNP cord-006870-f5w6fw6q 6429 9 given give VBN cord-006870-f5w6fw6q 6429 10 ongoing ongoing JJ cord-006870-f5w6fw6q 6429 11 vaginal vaginal JJ cord-006870-f5w6fw6q 6429 12 bleeding bleeding NN cord-006870-f5w6fw6q 6429 13 . . . cord-006870-f5w6fw6q 6430 1 The the DT cord-006870-f5w6fw6q 6430 2 decision decision NN cord-006870-f5w6fw6q 6430 3 was be VBD cord-006870-f5w6fw6q 6430 4 made make VBN cord-006870-f5w6fw6q 6430 5 to to TO cord-006870-f5w6fw6q 6430 6 proceed proceed VB cord-006870-f5w6fw6q 6430 7 with with IN cord-006870-f5w6fw6q 6430 8 mechanical mechanical JJ cord-006870-f5w6fw6q 6430 9 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 6430 10 when when WRB cord-006870-f5w6fw6q 6430 11 her -PRON- PRP$ cord-006870-f5w6fw6q 6430 12 exam exam NN cord-006870-f5w6fw6q 6430 13 worsened worsen VBD cord-006870-f5w6fw6q 6430 14 to to IN cord-006870-f5w6fw6q 6430 15 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6430 16 12 12 CD cord-006870-f5w6fw6q 6430 17 . . . cord-006870-f5w6fw6q 6431 1 The the DT cord-006870-f5w6fw6q 6431 2 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 6431 3 was be VBD cord-006870-f5w6fw6q 6431 4 successful successful JJ cord-006870-f5w6fw6q 6431 5 with with IN cord-006870-f5w6fw6q 6431 6 TICI TICI NNP cord-006870-f5w6fw6q 6431 7 2C 2c CD cord-006870-f5w6fw6q 6431 8 reperfusion reperfusion NN cord-006870-f5w6fw6q 6431 9 . . . cord-006870-f5w6fw6q 6432 1 She -PRON- PRP cord-006870-f5w6fw6q 6432 2 was be VBD cord-006870-f5w6fw6q 6432 3 discharged discharge VBN cord-006870-f5w6fw6q 6432 4 home home NN cord-006870-f5w6fw6q 6432 5 4 4 CD cord-006870-f5w6fw6q 6432 6 days day NNS cord-006870-f5w6fw6q 6432 7 later later RB cord-006870-f5w6fw6q 6432 8 with with IN cord-006870-f5w6fw6q 6432 9 a a DT cord-006870-f5w6fw6q 6432 10 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6432 11 of of IN cord-006870-f5w6fw6q 6432 12 zero zero CD cord-006870-f5w6fw6q 6432 13 . . . cord-006870-f5w6fw6q 6433 1 A a DT cord-006870-f5w6fw6q 6433 2 30Y 30y CD cord-006870-f5w6fw6q 6433 3 G1P1 G1P1 NNP cord-006870-f5w6fw6q 6433 4 presented present VBD cord-006870-f5w6fw6q 6433 5 4 4 CD cord-006870-f5w6fw6q 6433 6 days day NNS cord-006870-f5w6fw6q 6433 7 post post NN cord-006870-f5w6fw6q 6433 8 - - JJ cord-006870-f5w6fw6q 6433 9 partum partum JJ cord-006870-f5w6fw6q 6433 10 with with IN cord-006870-f5w6fw6q 6433 11 new new JJ cord-006870-f5w6fw6q 6433 12 onset onset NN cord-006870-f5w6fw6q 6433 13 of of IN cord-006870-f5w6fw6q 6433 14 left left JJ cord-006870-f5w6fw6q 6433 15 facial facial JJ cord-006870-f5w6fw6q 6433 16 droop droop NN cord-006870-f5w6fw6q 6433 17 and and CC cord-006870-f5w6fw6q 6433 18 slurred slur VBN cord-006870-f5w6fw6q 6433 19 speech speech NN cord-006870-f5w6fw6q 6433 20 ( ( -LRB- cord-006870-f5w6fw6q 6433 21 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6433 22 2 2 CD cord-006870-f5w6fw6q 6433 23 ) ) -RRB- cord-006870-f5w6fw6q 6433 24 . . . cord-006870-f5w6fw6q 6434 1 Imaging imaging NN cord-006870-f5w6fw6q 6434 2 showed show VBD cord-006870-f5w6fw6q 6434 3 right right JJ cord-006870-f5w6fw6q 6434 4 M1 M1 NNP cord-006870-f5w6fw6q 6434 5 cutoff cutoff NN cord-006870-f5w6fw6q 6434 6 with with IN cord-006870-f5w6fw6q 6434 7 reconstitution reconstitution NN cord-006870-f5w6fw6q 6434 8 , , , cord-006870-f5w6fw6q 6434 9 but but CC cord-006870-f5w6fw6q 6434 10 with with IN cord-006870-f5w6fw6q 6434 11 significant significant JJ cord-006870-f5w6fw6q 6434 12 associated associate VBN cord-006870-f5w6fw6q 6434 13 penumbra penumbra NN cord-006870-f5w6fw6q 6434 14 . . . cord-006870-f5w6fw6q 6435 1 Acute acute JJ cord-006870-f5w6fw6q 6435 2 worsening worsening NN cord-006870-f5w6fw6q 6435 3 of of IN cord-006870-f5w6fw6q 6435 4 exam exam NN cord-006870-f5w6fw6q 6435 5 post post NNP cord-006870-f5w6fw6q 6435 6 tPA tPA NNP cord-006870-f5w6fw6q 6435 7 triggered trigger VBD cord-006870-f5w6fw6q 6435 8 a a DT cord-006870-f5w6fw6q 6435 9 push push NN cord-006870-f5w6fw6q 6435 10 for for IN cord-006870-f5w6fw6q 6435 11 mechanical mechanical JJ cord-006870-f5w6fw6q 6435 12 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 6435 13 achieving achieve VBG cord-006870-f5w6fw6q 6435 14 a a DT cord-006870-f5w6fw6q 6435 15 TICI TICI NNP cord-006870-f5w6fw6q 6435 16 3 3 CD cord-006870-f5w6fw6q 6435 17 recanalization recanalization NN cord-006870-f5w6fw6q 6435 18 . . . cord-006870-f5w6fw6q 6436 1 Post post NN cord-006870-f5w6fw6q 6436 2 procedure procedure NN cord-006870-f5w6fw6q 6437 1 the the DT cord-006870-f5w6fw6q 6437 2 patient patient NN cord-006870-f5w6fw6q 6437 3 's 's POS cord-006870-f5w6fw6q 6437 4 only only JJ cord-006870-f5w6fw6q 6437 5 symptom symptom NN cord-006870-f5w6fw6q 6437 6 was be VBD cord-006870-f5w6fw6q 6437 7 decreased decrease VBN cord-006870-f5w6fw6q 6437 8 sensation sensation NN cord-006870-f5w6fw6q 6437 9 in in IN cord-006870-f5w6fw6q 6437 10 left left JJ cord-006870-f5w6fw6q 6437 11 fingertips fingertip NNS cord-006870-f5w6fw6q 6437 12 . . . cord-006870-f5w6fw6q 6438 1 At at IN cord-006870-f5w6fw6q 6438 2 30-day 30-day CD cord-006870-f5w6fw6q 6438 3 follow follow VB cord-006870-f5w6fw6q 6438 4 up up RP cord-006870-f5w6fw6q 6438 5 the the DT cord-006870-f5w6fw6q 6438 6 patient patient NN cord-006870-f5w6fw6q 6438 7 had have VBD cord-006870-f5w6fw6q 6438 8 returned return VBN cord-006870-f5w6fw6q 6438 9 to to IN cord-006870-f5w6fw6q 6438 10 her -PRON- PRP$ cord-006870-f5w6fw6q 6438 11 baseline baseline NN cord-006870-f5w6fw6q 6438 12 with with IN cord-006870-f5w6fw6q 6438 13 a a DT cord-006870-f5w6fw6q 6438 14 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6438 15 of of IN cord-006870-f5w6fw6q 6438 16 zero zero CD cord-006870-f5w6fw6q 6438 17 . . . cord-006870-f5w6fw6q 6439 1 Endovascular endovascular JJ cord-006870-f5w6fw6q 6439 2 and and CC cord-006870-f5w6fw6q 6439 3 pharmacologic pharmacologic JJ cord-006870-f5w6fw6q 6439 4 revascularization revascularization NN cord-006870-f5w6fw6q 6439 5 therapy therapy NN cord-006870-f5w6fw6q 6439 6 should should MD cord-006870-f5w6fw6q 6439 7 be be VB cord-006870-f5w6fw6q 6439 8 considered consider VBN cord-006870-f5w6fw6q 6439 9 on on IN cord-006870-f5w6fw6q 6439 10 an an DT cord-006870-f5w6fw6q 6439 11 individual individual JJ cord-006870-f5w6fw6q 6439 12 basis basis NN cord-006870-f5w6fw6q 6439 13 in in IN cord-006870-f5w6fw6q 6439 14 the the DT cord-006870-f5w6fw6q 6439 15 peripartum peripartum NN cord-006870-f5w6fw6q 6439 16 population population NN cord-006870-f5w6fw6q 6439 17 . . . cord-006870-f5w6fw6q 6440 1 Current current JJ cord-006870-f5w6fw6q 6440 2 literature literature NN cord-006870-f5w6fw6q 6440 3 is be VBZ cord-006870-f5w6fw6q 6440 4 limited limit VBN cord-006870-f5w6fw6q 6440 5 to to IN cord-006870-f5w6fw6q 6440 6 case case NN cord-006870-f5w6fw6q 6440 7 reports report NNS cord-006870-f5w6fw6q 6440 8 /case /case , cord-006870-f5w6fw6q 6440 9 series series NN cord-006870-f5w6fw6q 6440 10 . . . cord-006870-f5w6fw6q 6441 1 Larger large JJR cord-006870-f5w6fw6q 6441 2 multicenter multicenter JJ cord-006870-f5w6fw6q 6441 3 trials trial NNS cord-006870-f5w6fw6q 6441 4 are be VBP cord-006870-f5w6fw6q 6441 5 warranted warrant VBN cord-006870-f5w6fw6q 6441 6 and and CC cord-006870-f5w6fw6q 6441 7 anticipated anticipate VBN cord-006870-f5w6fw6q 6441 8 in in IN cord-006870-f5w6fw6q 6441 9 the the DT cord-006870-f5w6fw6q 6441 10 near near JJ cord-006870-f5w6fw6q 6441 11 future future NN cord-006870-f5w6fw6q 6441 12 . . . cord-006870-f5w6fw6q 6442 1 While while IN cord-006870-f5w6fw6q 6442 2 the the DT cord-006870-f5w6fw6q 6442 3 optimal optimal JJ cord-006870-f5w6fw6q 6442 4 duration duration NN cord-006870-f5w6fw6q 6442 5 of of IN cord-006870-f5w6fw6q 6442 6 burst burst NN cord-006870-f5w6fw6q 6442 7 suppression suppression NN cord-006870-f5w6fw6q 6442 8 for for IN cord-006870-f5w6fw6q 6442 9 status status NN cord-006870-f5w6fw6q 6442 10 epilepticus epilepticus NN cord-006870-f5w6fw6q 6442 11 ( ( -LRB- cord-006870-f5w6fw6q 6442 12 SE SE NNP cord-006870-f5w6fw6q 6442 13 ) ) -RRB- cord-006870-f5w6fw6q 6442 14 has have VBZ cord-006870-f5w6fw6q 6442 15 not not RB cord-006870-f5w6fw6q 6442 16 been be VBN cord-006870-f5w6fw6q 6442 17 established establish VBN cord-006870-f5w6fw6q 6442 18 , , , cord-006870-f5w6fw6q 6442 19 burst burst VB cord-006870-f5w6fw6q 6442 20 suppression suppression NN cord-006870-f5w6fw6q 6442 21 poses pose VBZ cord-006870-f5w6fw6q 6442 22 significant significant JJ cord-006870-f5w6fw6q 6442 23 morbidity morbidity NN cord-006870-f5w6fw6q 6442 24 that that WDT cord-006870-f5w6fw6q 6442 25 may may MD cord-006870-f5w6fw6q 6442 26 be be VB cord-006870-f5w6fw6q 6442 27 dependent dependent JJ cord-006870-f5w6fw6q 6442 28 on on IN cord-006870-f5w6fw6q 6442 29 the the DT cord-006870-f5w6fw6q 6442 30 amount amount NN cord-006870-f5w6fw6q 6442 31 of of IN cord-006870-f5w6fw6q 6442 32 time time NN cord-006870-f5w6fw6q 6442 33 spent spend VBN cord-006870-f5w6fw6q 6442 34 in in IN cord-006870-f5w6fw6q 6442 35 burst burst NN cord-006870-f5w6fw6q 6442 36 suppression suppression NN cord-006870-f5w6fw6q 6442 37 . . . cord-006870-f5w6fw6q 6443 1 Herein herein RB cord-006870-f5w6fw6q 6443 2 , , , cord-006870-f5w6fw6q 6443 3 we -PRON- PRP cord-006870-f5w6fw6q 6443 4 report report VBP cord-006870-f5w6fw6q 6443 5 a a DT cord-006870-f5w6fw6q 6443 6 case case NN cord-006870-f5w6fw6q 6443 7 of of IN cord-006870-f5w6fw6q 6443 8 SE SE NNP cord-006870-f5w6fw6q 6443 9 that that WDT cord-006870-f5w6fw6q 6443 10 resolved resolve VBD cord-006870-f5w6fw6q 6443 11 after after IN cord-006870-f5w6fw6q 6443 12 ultra ultra JJ cord-006870-f5w6fw6q 6443 13 - - JJ cord-006870-f5w6fw6q 6443 14 short short JJ cord-006870-f5w6fw6q 6443 15 burst burst NN cord-006870-f5w6fw6q 6443 16 suppression suppression NN cord-006870-f5w6fw6q 6443 17 . . . cord-006870-f5w6fw6q 6444 1 Case case NN cord-006870-f5w6fw6q 6444 2 report report NN cord-006870-f5w6fw6q 6444 3 . . . cord-006870-f5w6fw6q 6445 1 A a DT cord-006870-f5w6fw6q 6445 2 74 74 CD cord-006870-f5w6fw6q 6445 3 year year NN cord-006870-f5w6fw6q 6445 4 - - HYPH cord-006870-f5w6fw6q 6445 5 old old JJ cord-006870-f5w6fw6q 6445 6 female female NN cord-006870-f5w6fw6q 6445 7 was be VBD cord-006870-f5w6fw6q 6445 8 admitted admit VBN cord-006870-f5w6fw6q 6445 9 to to IN cord-006870-f5w6fw6q 6445 10 the the DT cord-006870-f5w6fw6q 6445 11 neuro neuro NNP cord-006870-f5w6fw6q 6445 12 - - HYPH cord-006870-f5w6fw6q 6445 13 intensive intensive JJ cord-006870-f5w6fw6q 6445 14 care care NN cord-006870-f5w6fw6q 6445 15 unit unit NN cord-006870-f5w6fw6q 6445 16 after after IN cord-006870-f5w6fw6q 6445 17 experiencing experience VBG cord-006870-f5w6fw6q 6445 18 several several JJ cord-006870-f5w6fw6q 6445 19 brief brief JJ cord-006870-f5w6fw6q 6445 20 tonic tonic NN cord-006870-f5w6fw6q 6445 21 - - HYPH cord-006870-f5w6fw6q 6445 22 clonic clonic JJ cord-006870-f5w6fw6q 6445 23 seizures seizure NNS cord-006870-f5w6fw6q 6445 24 characterized characterize VBN cord-006870-f5w6fw6q 6445 25 by by IN cord-006870-f5w6fw6q 6445 26 right right JJ cord-006870-f5w6fw6q 6445 27 - - HYPH cord-006870-f5w6fw6q 6445 28 sided sided JJ cord-006870-f5w6fw6q 6445 29 shaking shaking NN cord-006870-f5w6fw6q 6445 30 and and CC cord-006870-f5w6fw6q 6445 31 left left JJ cord-006870-f5w6fw6q 6445 32 - - HYPH cord-006870-f5w6fw6q 6445 33 sided sided JJ cord-006870-f5w6fw6q 6445 34 head head NN cord-006870-f5w6fw6q 6445 35 turn turn VB cord-006870-f5w6fw6q 6445 36 . . . cord-006870-f5w6fw6q 6446 1 Despite despite IN cord-006870-f5w6fw6q 6446 2 lorazepam lorazepam NN cord-006870-f5w6fw6q 6446 3 and and CC cord-006870-f5w6fw6q 6446 4 levetiracetam levetiracetam NNP cord-006870-f5w6fw6q 6446 5 administration administration NN cord-006870-f5w6fw6q 6446 6 , , , cord-006870-f5w6fw6q 6446 7 the the DT cord-006870-f5w6fw6q 6446 8 patient patient NN cord-006870-f5w6fw6q 6446 9 did do VBD cord-006870-f5w6fw6q 6446 10 not not RB cord-006870-f5w6fw6q 6446 11 return return VB cord-006870-f5w6fw6q 6446 12 to to IN cord-006870-f5w6fw6q 6446 13 baseline baseline NN cord-006870-f5w6fw6q 6446 14 and and CC cord-006870-f5w6fw6q 6446 15 was be VBD cord-006870-f5w6fw6q 6446 16 transferred transfer VBN cord-006870-f5w6fw6q 6446 17 to to IN cord-006870-f5w6fw6q 6446 18 our -PRON- PRP$ cord-006870-f5w6fw6q 6446 19 unit unit NN cord-006870-f5w6fw6q 6446 20 . . . cord-006870-f5w6fw6q 6447 1 On on IN cord-006870-f5w6fw6q 6447 2 presentation presentation NN cord-006870-f5w6fw6q 6447 3 , , , cord-006870-f5w6fw6q 6447 4 her -PRON- PRP$ cord-006870-f5w6fw6q 6447 5 workup workup NN cord-006870-f5w6fw6q 6447 6 revealed reveal VBD cord-006870-f5w6fw6q 6447 7 a a DT cord-006870-f5w6fw6q 6447 8 leukocytosis leukocytosis NN cord-006870-f5w6fw6q 6447 9 and and CC cord-006870-f5w6fw6q 6447 10 a a DT cord-006870-f5w6fw6q 6447 11 glucose glucose NN cord-006870-f5w6fw6q 6447 12 level level NN cord-006870-f5w6fw6q 6447 13 > > XX cord-006870-f5w6fw6q 6447 14 300 300 CD cord-006870-f5w6fw6q 6447 15 mg mg NN cord-006870-f5w6fw6q 6447 16 / / SYM cord-006870-f5w6fw6q 6447 17 dL. dl. NN cord-006870-f5w6fw6q 6447 18 Lumbar Lumbar NNP cord-006870-f5w6fw6q 6447 19 puncture puncture NN cord-006870-f5w6fw6q 6447 20 showed show VBD cord-006870-f5w6fw6q 6447 21 a a DT cord-006870-f5w6fw6q 6447 22 mild mild JJ cord-006870-f5w6fw6q 6447 23 pleocytosis pleocytosis NN cord-006870-f5w6fw6q 6447 24 for for IN cord-006870-f5w6fw6q 6447 25 which which WDT cord-006870-f5w6fw6q 6447 26 broad broad JJ cord-006870-f5w6fw6q 6447 27 spectrum spectrum NN cord-006870-f5w6fw6q 6447 28 antibiotics antibiotic NNS cord-006870-f5w6fw6q 6447 29 were be VBD cord-006870-f5w6fw6q 6447 30 initiated initiate VBN cord-006870-f5w6fw6q 6447 31 . . . cord-006870-f5w6fw6q 6448 1 On on IN cord-006870-f5w6fw6q 6448 2 initial initial JJ cord-006870-f5w6fw6q 6448 3 examination examination NN cord-006870-f5w6fw6q 6448 4 , , , cord-006870-f5w6fw6q 6448 5 she -PRON- PRP cord-006870-f5w6fw6q 6448 6 was be VBD cord-006870-f5w6fw6q 6448 7 unresponsive unresponsive JJ cord-006870-f5w6fw6q 6448 8 and and CC cord-006870-f5w6fw6q 6448 9 was be VBD cord-006870-f5w6fw6q 6448 10 not not RB cord-006870-f5w6fw6q 6448 11 following follow VBG cord-006870-f5w6fw6q 6448 12 commands command NNS cord-006870-f5w6fw6q 6448 13 . . . cord-006870-f5w6fw6q 6449 1 Electroencephalogram Electroencephalogram NNP cord-006870-f5w6fw6q 6449 2 ( ( -LRB- cord-006870-f5w6fw6q 6449 3 EEG EEG NNP cord-006870-f5w6fw6q 6449 4 ) ) -RRB- cord-006870-f5w6fw6q 6449 5 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6449 6 frequent frequent JJ cord-006870-f5w6fw6q 6449 7 sharp sharp JJ cord-006870-f5w6fw6q 6449 8 and and CC cord-006870-f5w6fw6q 6449 9 slow slow JJ cord-006870-f5w6fw6q 6449 10 discharges discharge NNS cord-006870-f5w6fw6q 6449 11 in in IN cord-006870-f5w6fw6q 6449 12 the the DT cord-006870-f5w6fw6q 6449 13 right right JJ cord-006870-f5w6fw6q 6449 14 posterior posterior JJ cord-006870-f5w6fw6q 6449 15 quadrant quadrant NN cord-006870-f5w6fw6q 6449 16 with with IN cord-006870-f5w6fw6q 6449 17 generalization generalization NN cord-006870-f5w6fw6q 6449 18 ( ( -LRB- cord-006870-f5w6fw6q 6449 19 ~20 ~20 NFP cord-006870-f5w6fw6q 6449 20 seizures seizure NNS cord-006870-f5w6fw6q 6449 21 / / SYM cord-006870-f5w6fw6q 6449 22 hour hour NN cord-006870-f5w6fw6q 6449 23 ) ) -RRB- cord-006870-f5w6fw6q 6449 24 with with IN cord-006870-f5w6fw6q 6449 25 minimal minimal JJ cord-006870-f5w6fw6q 6449 26 improvement improvement NN cord-006870-f5w6fw6q 6449 27 following follow VBG cord-006870-f5w6fw6q 6449 28 levetiracetam levetiracetam NNS cord-006870-f5w6fw6q 6449 29 and and CC cord-006870-f5w6fw6q 6449 30 phenytoin phenytoin NNP cord-006870-f5w6fw6q 6449 31 administration administration NN cord-006870-f5w6fw6q 6449 32 . . . cord-006870-f5w6fw6q 6450 1 Given give VBN cord-006870-f5w6fw6q 6450 2 the the DT cord-006870-f5w6fw6q 6450 3 refractory refractory JJ cord-006870-f5w6fw6q 6450 4 nature nature NN cord-006870-f5w6fw6q 6450 5 of of IN cord-006870-f5w6fw6q 6450 6 seizures seizure NNS cord-006870-f5w6fw6q 6450 7 , , , cord-006870-f5w6fw6q 6450 8 the the DT cord-006870-f5w6fw6q 6450 9 patient patient NN cord-006870-f5w6fw6q 6450 10 was be VBD cord-006870-f5w6fw6q 6450 11 intubated intubate VBN cord-006870-f5w6fw6q 6450 12 and and CC cord-006870-f5w6fw6q 6450 13 treated treat VBN cord-006870-f5w6fw6q 6450 14 with with IN cord-006870-f5w6fw6q 6450 15 general general JJ cord-006870-f5w6fw6q 6450 16 anesthetics anesthetic NNS cord-006870-f5w6fw6q 6450 17 . . . cord-006870-f5w6fw6q 6451 1 Using use VBG cord-006870-f5w6fw6q 6451 2 Propofol Propofol NNP cord-006870-f5w6fw6q 6451 3 , , , cord-006870-f5w6fw6q 6451 4 burst burst VBN cord-006870-f5w6fw6q 6451 5 suppression suppression NN cord-006870-f5w6fw6q 6451 6 was be VBD cord-006870-f5w6fw6q 6451 7 achieved achieve VBN cord-006870-f5w6fw6q 6451 8 ( ( -LRB- cord-006870-f5w6fw6q 6451 9 consisting consist VBG cord-006870-f5w6fw6q 6451 10 of of IN cord-006870-f5w6fw6q 6451 11 1 1 CD cord-006870-f5w6fw6q 6451 12 - - SYM cord-006870-f5w6fw6q 6451 13 2 2 CD cord-006870-f5w6fw6q 6451 14 s s POS cord-006870-f5w6fw6q 6451 15 bursts burst NNS cord-006870-f5w6fw6q 6451 16 with with IN cord-006870-f5w6fw6q 6451 17 intermixed intermixed JJ cord-006870-f5w6fw6q 6451 18 suppressions suppression NNS cord-006870-f5w6fw6q 6451 19 ) ) -RRB- cord-006870-f5w6fw6q 6451 20 and and CC cord-006870-f5w6fw6q 6451 21 was be VBD cord-006870-f5w6fw6q 6451 22 continued continue VBN cord-006870-f5w6fw6q 6451 23 for for IN cord-006870-f5w6fw6q 6451 24 < < XX cord-006870-f5w6fw6q 6451 25 2 2 CD cord-006870-f5w6fw6q 6451 26 hours hour NNS cord-006870-f5w6fw6q 6451 27 . . . cord-006870-f5w6fw6q 6452 1 Following follow VBG cord-006870-f5w6fw6q 6452 2 weaning wean VBG cord-006870-f5w6fw6q 6452 3 , , , cord-006870-f5w6fw6q 6452 4 the the DT cord-006870-f5w6fw6q 6452 5 patient patient NN cord-006870-f5w6fw6q 6452 6 had have VBD cord-006870-f5w6fw6q 6452 7 no no DT cord-006870-f5w6fw6q 6452 8 further further JJ cord-006870-f5w6fw6q 6452 9 evidence evidence NN cord-006870-f5w6fw6q 6452 10 of of IN cord-006870-f5w6fw6q 6452 11 seizures seizure NNS cord-006870-f5w6fw6q 6452 12 , , , cord-006870-f5w6fw6q 6452 13 and and CC cord-006870-f5w6fw6q 6452 14 EEG EEG NNP cord-006870-f5w6fw6q 6452 15 showed show VBD cord-006870-f5w6fw6q 6452 16 lateralized lateralized JJ cord-006870-f5w6fw6q 6452 17 periodic periodic JJ cord-006870-f5w6fw6q 6452 18 discharges discharge NNS cord-006870-f5w6fw6q 6452 19 in in IN cord-006870-f5w6fw6q 6452 20 the the DT cord-006870-f5w6fw6q 6452 21 right right JJ cord-006870-f5w6fw6q 6452 22 occipital occipital JJ cord-006870-f5w6fw6q 6452 23 lobe lobe NN cord-006870-f5w6fw6q 6452 24 . . . cord-006870-f5w6fw6q 6453 1 MRI MRI NNP cord-006870-f5w6fw6q 6453 2 did do VBD cord-006870-f5w6fw6q 6453 3 not not RB cord-006870-f5w6fw6q 6453 4 demonstrate demonstrate VB cord-006870-f5w6fw6q 6453 5 an an DT cord-006870-f5w6fw6q 6453 6 occipital occipital JJ cord-006870-f5w6fw6q 6453 7 focus focus NN cord-006870-f5w6fw6q 6453 8 , , , cord-006870-f5w6fw6q 6453 9 but but CC cord-006870-f5w6fw6q 6453 10 did do VBD cord-006870-f5w6fw6q 6453 11 reveal reveal VB cord-006870-f5w6fw6q 6453 12 cortical cortical JJ cord-006870-f5w6fw6q 6453 13 diffusion diffusion NN cord-006870-f5w6fw6q 6453 14 restriction restriction NN cord-006870-f5w6fw6q 6453 15 in in IN cord-006870-f5w6fw6q 6453 16 the the DT cord-006870-f5w6fw6q 6453 17 bilateral bilateral JJ cord-006870-f5w6fw6q 6453 18 posterior posterior JJ cord-006870-f5w6fw6q 6453 19 hemispheres hemisphere NNS cord-006870-f5w6fw6q 6453 20 . . . cord-006870-f5w6fw6q 6454 1 The the DT cord-006870-f5w6fw6q 6454 2 patient patient NN cord-006870-f5w6fw6q 6454 3 was be VBD cord-006870-f5w6fw6q 6454 4 extubated extubate VBN cord-006870-f5w6fw6q 6454 5 the the DT cord-006870-f5w6fw6q 6454 6 following following JJ cord-006870-f5w6fw6q 6454 7 morning morning NN cord-006870-f5w6fw6q 6454 8 , , , cord-006870-f5w6fw6q 6454 9 and and CC cord-006870-f5w6fw6q 6454 10 was be VBD cord-006870-f5w6fw6q 6454 11 transferred transfer VBN cord-006870-f5w6fw6q 6454 12 to to IN cord-006870-f5w6fw6q 6454 13 the the DT cord-006870-f5w6fw6q 6454 14 neurology neurology NN cord-006870-f5w6fw6q 6454 15 floor floor NN cord-006870-f5w6fw6q 6454 16 two two CD cord-006870-f5w6fw6q 6454 17 days day NNS cord-006870-f5w6fw6q 6454 18 later later RB cord-006870-f5w6fw6q 6454 19 . . . cord-006870-f5w6fw6q 6455 1 This this DT cord-006870-f5w6fw6q 6455 2 case case NN cord-006870-f5w6fw6q 6455 3 provides provide VBZ cord-006870-f5w6fw6q 6455 4 evidence evidence NN cord-006870-f5w6fw6q 6455 5 that that IN cord-006870-f5w6fw6q 6455 6 in in IN cord-006870-f5w6fw6q 6455 7 certain certain JJ cord-006870-f5w6fw6q 6455 8 situations situation NNS cord-006870-f5w6fw6q 6455 9 , , , cord-006870-f5w6fw6q 6455 10 relatively relatively RB cord-006870-f5w6fw6q 6455 11 brief brief JJ cord-006870-f5w6fw6q 6455 12 periods period NNS cord-006870-f5w6fw6q 6455 13 of of IN cord-006870-f5w6fw6q 6455 14 burst burst NN cord-006870-f5w6fw6q 6455 15 suppression suppression NN cord-006870-f5w6fw6q 6455 16 in in IN cord-006870-f5w6fw6q 6455 17 SE SE NNP cord-006870-f5w6fw6q 6455 18 can can MD cord-006870-f5w6fw6q 6455 19 serve serve VB cord-006870-f5w6fw6q 6455 20 as as IN cord-006870-f5w6fw6q 6455 21 a a DT cord-006870-f5w6fw6q 6455 22 " " `` cord-006870-f5w6fw6q 6455 23 reset reset NN cord-006870-f5w6fw6q 6455 24 switch switch NN cord-006870-f5w6fw6q 6455 25 " " '' cord-006870-f5w6fw6q 6455 26 , , , cord-006870-f5w6fw6q 6455 27 allowing allow VBG cord-006870-f5w6fw6q 6455 28 for for IN cord-006870-f5w6fw6q 6455 29 resolution resolution NN cord-006870-f5w6fw6q 6455 30 of of IN cord-006870-f5w6fw6q 6455 31 seizures seizure NNS cord-006870-f5w6fw6q 6455 32 while while IN cord-006870-f5w6fw6q 6455 33 minimizing minimize VBG cord-006870-f5w6fw6q 6455 34 toxicities toxicity NNS cord-006870-f5w6fw6q 6455 35 associated associate VBN cord-006870-f5w6fw6q 6455 36 with with IN cord-006870-f5w6fw6q 6455 37 prolonged prolonged JJ cord-006870-f5w6fw6q 6455 38 burst burst NN cord-006870-f5w6fw6q 6455 39 suppression suppression NN cord-006870-f5w6fw6q 6455 40 . . . cord-006870-f5w6fw6q 6456 1 Further further JJ cord-006870-f5w6fw6q 6456 2 studies study NNS cord-006870-f5w6fw6q 6456 3 to to TO cord-006870-f5w6fw6q 6456 4 determine determine VB cord-006870-f5w6fw6q 6456 5 which which WDT cord-006870-f5w6fw6q 6456 6 patients patient NNS cord-006870-f5w6fw6q 6456 7 may may MD cord-006870-f5w6fw6q 6456 8 benefit benefit VB cord-006870-f5w6fw6q 6456 9 from from IN cord-006870-f5w6fw6q 6456 10 ultrashort ultrashort JJ cord-006870-f5w6fw6q 6456 11 burst burst NN cord-006870-f5w6fw6q 6456 12 suppression suppression NN cord-006870-f5w6fw6q 6456 13 are be VBP cord-006870-f5w6fw6q 6456 14 warranted warrant VBN cord-006870-f5w6fw6q 6456 15 . . . cord-006870-f5w6fw6q 6457 1 There there EX cord-006870-f5w6fw6q 6457 2 are be VBP cord-006870-f5w6fw6q 6457 3 two two CD cord-006870-f5w6fw6q 6457 4 systems system NNS cord-006870-f5w6fw6q 6457 5 of of IN cord-006870-f5w6fw6q 6457 6 facial facial JJ cord-006870-f5w6fw6q 6457 7 control control NN cord-006870-f5w6fw6q 6457 8 , , , cord-006870-f5w6fw6q 6457 9 voluntary voluntary JJ cord-006870-f5w6fw6q 6457 10 and and CC cord-006870-f5w6fw6q 6457 11 emotional emotional JJ cord-006870-f5w6fw6q 6457 12 ; ; : cord-006870-f5w6fw6q 6457 13 these these DT cord-006870-f5w6fw6q 6457 14 are be VBP cord-006870-f5w6fw6q 6457 15 independent independent JJ cord-006870-f5w6fw6q 6457 16 up up IN cord-006870-f5w6fw6q 6457 17 to to IN cord-006870-f5w6fw6q 6457 18 the the DT cord-006870-f5w6fw6q 6457 19 level level NN cord-006870-f5w6fw6q 6457 20 of of IN cord-006870-f5w6fw6q 6457 21 the the DT cord-006870-f5w6fw6q 6457 22 facial facial JJ cord-006870-f5w6fw6q 6457 23 nucleus nucleus NN cord-006870-f5w6fw6q 6457 24 . . . cord-006870-f5w6fw6q 6458 1 We -PRON- PRP cord-006870-f5w6fw6q 6458 2 described describe VBD cord-006870-f5w6fw6q 6458 3 a a DT cord-006870-f5w6fw6q 6458 4 case case NN cord-006870-f5w6fw6q 6458 5 of of IN cord-006870-f5w6fw6q 6458 6 a a DT cord-006870-f5w6fw6q 6458 7 patient patient NN cord-006870-f5w6fw6q 6458 8 who who WP cord-006870-f5w6fw6q 6458 9 presented present VBD cord-006870-f5w6fw6q 6458 10 with with IN cord-006870-f5w6fw6q 6458 11 isolated isolate VBN cord-006870-f5w6fw6q 6458 12 emotional emotional JJ cord-006870-f5w6fw6q 6458 13 facial facial JJ cord-006870-f5w6fw6q 6458 14 palsy palsy NN cord-006870-f5w6fw6q 6458 15 after after IN cord-006870-f5w6fw6q 6458 16 intracerebral intracerebral JJ cord-006870-f5w6fw6q 6458 17 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6458 18 ( ( -LRB- cord-006870-f5w6fw6q 6458 19 ICH ICH NNP cord-006870-f5w6fw6q 6458 20 ) ) -RRB- cord-006870-f5w6fw6q 6458 21 . . . cord-006870-f5w6fw6q 6459 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 6459 2 review review NN cord-006870-f5w6fw6q 6459 3 of of IN cord-006870-f5w6fw6q 6459 4 a a DT cord-006870-f5w6fw6q 6459 5 case case NN cord-006870-f5w6fw6q 6459 6 admitted admit VBN cord-006870-f5w6fw6q 6459 7 to to IN cord-006870-f5w6fw6q 6459 8 the the DT cord-006870-f5w6fw6q 6459 9 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 6459 10 Care Care NNP cord-006870-f5w6fw6q 6459 11 Unit Unit NNP cord-006870-f5w6fw6q 6459 12 ( ( -LRB- cord-006870-f5w6fw6q 6459 13 NCCU NCCU NNP cord-006870-f5w6fw6q 6459 14 ) ) -RRB- cord-006870-f5w6fw6q 6459 15 of of IN cord-006870-f5w6fw6q 6459 16 the the DT cord-006870-f5w6fw6q 6459 17 Johns Johns NNP cord-006870-f5w6fw6q 6459 18 Hopkins Hopkins NNP cord-006870-f5w6fw6q 6459 19 Hospital Hospital NNP cord-006870-f5w6fw6q 6459 20 . . . cord-006870-f5w6fw6q 6460 1 A a DT cord-006870-f5w6fw6q 6460 2 29 29 CD cord-006870-f5w6fw6q 6460 3 year year NN cord-006870-f5w6fw6q 6460 4 - - HYPH cord-006870-f5w6fw6q 6460 5 old old JJ cord-006870-f5w6fw6q 6460 6 woman woman NN cord-006870-f5w6fw6q 6460 7 with with IN cord-006870-f5w6fw6q 6460 8 history history NN cord-006870-f5w6fw6q 6460 9 of of IN cord-006870-f5w6fw6q 6460 10 migraines migraine NNS cord-006870-f5w6fw6q 6460 11 who who WP cord-006870-f5w6fw6q 6460 12 presented present VBD cord-006870-f5w6fw6q 6460 13 to to IN cord-006870-f5w6fw6q 6460 14 the the DT cord-006870-f5w6fw6q 6460 15 emergency emergency NN cord-006870-f5w6fw6q 6460 16 room room NN cord-006870-f5w6fw6q 6460 17 after after IN cord-006870-f5w6fw6q 6460 18 a a DT cord-006870-f5w6fw6q 6460 19 colleague colleague NN cord-006870-f5w6fw6q 6460 20 noticed notice VBD cord-006870-f5w6fw6q 6460 21 she -PRON- PRP cord-006870-f5w6fw6q 6460 22 was be VBD cord-006870-f5w6fw6q 6460 23 not not RB cord-006870-f5w6fw6q 6460 24 moving move VBG cord-006870-f5w6fw6q 6460 25 the the DT cord-006870-f5w6fw6q 6460 26 left left JJ cord-006870-f5w6fw6q 6460 27 lower low JJR cord-006870-f5w6fw6q 6460 28 side side NN cord-006870-f5w6fw6q 6460 29 of of IN cord-006870-f5w6fw6q 6460 30 her -PRON- PRP$ cord-006870-f5w6fw6q 6460 31 face face NN cord-006870-f5w6fw6q 6460 32 when when WRB cord-006870-f5w6fw6q 6460 33 she -PRON- PRP cord-006870-f5w6fw6q 6460 34 smiled smile VBD cord-006870-f5w6fw6q 6460 35 . . . cord-006870-f5w6fw6q 6461 1 Head Head NNP cord-006870-f5w6fw6q 6461 2 CT CT NNP cord-006870-f5w6fw6q 6461 3 showed show VBD cord-006870-f5w6fw6q 6461 4 a a DT cord-006870-f5w6fw6q 6461 5 large large JJ cord-006870-f5w6fw6q 6461 6 right right JJ cord-006870-f5w6fw6q 6461 7 frontal frontal JJ cord-006870-f5w6fw6q 6461 8 ICH ICH NNP cord-006870-f5w6fw6q 6461 9 involving involve VBG cord-006870-f5w6fw6q 6461 10 the the DT cord-006870-f5w6fw6q 6461 11 medial medial JJ cord-006870-f5w6fw6q 6461 12 frontal frontal JJ cord-006870-f5w6fw6q 6461 13 lobes lobe NNS cord-006870-f5w6fw6q 6461 14 and and CC cord-006870-f5w6fw6q 6461 15 anterior anterior JJ cord-006870-f5w6fw6q 6461 16 thalami thalami NNP cord-006870-f5w6fw6q 6461 17 . . . cord-006870-f5w6fw6q 6462 1 On on IN cord-006870-f5w6fw6q 6462 2 review review NN cord-006870-f5w6fw6q 6462 3 of of IN cord-006870-f5w6fw6q 6462 4 an an DT cord-006870-f5w6fw6q 6462 5 old old JJ cord-006870-f5w6fw6q 6462 6 MRI MRI NNP cord-006870-f5w6fw6q 6462 7 done do VBN cord-006870-f5w6fw6q 6462 8 , , , cord-006870-f5w6fw6q 6462 9 an an DT cord-006870-f5w6fw6q 6462 10 underlying underlie VBG cord-006870-f5w6fw6q 6462 11 developmental developmental JJ cord-006870-f5w6fw6q 6462 12 venous venous JJ cord-006870-f5w6fw6q 6462 13 anomaly anomaly NN cord-006870-f5w6fw6q 6462 14 with with IN cord-006870-f5w6fw6q 6462 15 an an DT cord-006870-f5w6fw6q 6462 16 associated associate VBN cord-006870-f5w6fw6q 6462 17 cavernoma cavernoma NN cord-006870-f5w6fw6q 6462 18 was be VBD cord-006870-f5w6fw6q 6462 19 seen see VBN cord-006870-f5w6fw6q 6462 20 . . . cord-006870-f5w6fw6q 6463 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6463 2 exam exam NN cord-006870-f5w6fw6q 6463 3 was be VBD cord-006870-f5w6fw6q 6463 4 notable notable JJ cord-006870-f5w6fw6q 6463 5 for for IN cord-006870-f5w6fw6q 6463 6 a a DT cord-006870-f5w6fw6q 6463 7 flattened flatten VBN cord-006870-f5w6fw6q 6463 8 emotional emotional JJ cord-006870-f5w6fw6q 6463 9 affect affect NN cord-006870-f5w6fw6q 6463 10 , , , cord-006870-f5w6fw6q 6463 11 no no DT cord-006870-f5w6fw6q 6463 12 facial facial JJ cord-006870-f5w6fw6q 6463 13 palsy palsy NN cord-006870-f5w6fw6q 6463 14 when when WRB cord-006870-f5w6fw6q 6463 15 asked ask VBN cord-006870-f5w6fw6q 6463 16 to to TO cord-006870-f5w6fw6q 6463 17 activate activate VB cord-006870-f5w6fw6q 6463 18 on on IN cord-006870-f5w6fw6q 6463 19 command command NN cord-006870-f5w6fw6q 6463 20 , , , cord-006870-f5w6fw6q 6463 21 but but CC cord-006870-f5w6fw6q 6463 22 a a DT cord-006870-f5w6fw6q 6463 23 facial facial JJ cord-006870-f5w6fw6q 6463 24 droop droop NN cord-006870-f5w6fw6q 6463 25 that that WDT cord-006870-f5w6fw6q 6463 26 occurred occur VBD cord-006870-f5w6fw6q 6463 27 in in IN cord-006870-f5w6fw6q 6463 28 the the DT cord-006870-f5w6fw6q 6463 29 context context NN cord-006870-f5w6fw6q 6463 30 of of IN cord-006870-f5w6fw6q 6463 31 her -PRON- PRP$ cord-006870-f5w6fw6q 6463 32 smiling smile VBG cord-006870-f5w6fw6q 6463 33 to to IN cord-006870-f5w6fw6q 6463 34 jokes joke NNS cord-006870-f5w6fw6q 6463 35 and and CC cord-006870-f5w6fw6q 6463 36 other other JJ cord-006870-f5w6fw6q 6463 37 humor humor NN cord-006870-f5w6fw6q 6463 38 . . . cord-006870-f5w6fw6q 6464 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6464 2 NCCU NCCU NNP cord-006870-f5w6fw6q 6464 3 course course NN cord-006870-f5w6fw6q 6464 4 was be VBD cord-006870-f5w6fw6q 6464 5 complicated complicate VBN cord-006870-f5w6fw6q 6464 6 with with IN cord-006870-f5w6fw6q 6464 7 significant significant JJ cord-006870-f5w6fw6q 6464 8 brain brain NN cord-006870-f5w6fw6q 6464 9 edema edema NN cord-006870-f5w6fw6q 6464 10 requiring require VBG cord-006870-f5w6fw6q 6464 11 osmotherapy osmotherapy NN cord-006870-f5w6fw6q 6464 12 up up IN cord-006870-f5w6fw6q 6464 13 to to TO cord-006870-f5w6fw6q 6464 14 3 3 CD cord-006870-f5w6fw6q 6464 15 weeks week NNS cord-006870-f5w6fw6q 6464 16 out out RP cord-006870-f5w6fw6q 6464 17 from from IN cord-006870-f5w6fw6q 6464 18 the the DT cord-006870-f5w6fw6q 6464 19 initial initial JJ cord-006870-f5w6fw6q 6464 20 insult insult NN cord-006870-f5w6fw6q 6464 21 with with IN cord-006870-f5w6fw6q 6464 22 self self NN cord-006870-f5w6fw6q 6464 23 - - HYPH cord-006870-f5w6fw6q 6464 24 limited limit VBN cord-006870-f5w6fw6q 6464 25 episodes episode NNS cord-006870-f5w6fw6q 6464 26 of of IN cord-006870-f5w6fw6q 6464 27 brain brain NN cord-006870-f5w6fw6q 6464 28 herniation herniation NN cord-006870-f5w6fw6q 6464 29 characterized characterize VBN cord-006870-f5w6fw6q 6464 30 by by IN cord-006870-f5w6fw6q 6464 31 extensor extensor NN cord-006870-f5w6fw6q 6464 32 posturing posturing NN cord-006870-f5w6fw6q 6464 33 , , , cord-006870-f5w6fw6q 6464 34 dilated dilated JJ cord-006870-f5w6fw6q 6464 35 pupils pupil NNS cord-006870-f5w6fw6q 6464 36 , , , cord-006870-f5w6fw6q 6464 37 hypertension hypertension NN cord-006870-f5w6fw6q 6464 38 , , , cord-006870-f5w6fw6q 6464 39 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 6464 40 and and CC cord-006870-f5w6fw6q 6464 41 tachycardia tachycardia NN cord-006870-f5w6fw6q 6464 42 . . . cord-006870-f5w6fw6q 6465 1 These these DT cord-006870-f5w6fw6q 6465 2 were be VBD cord-006870-f5w6fw6q 6465 3 initially initially RB cord-006870-f5w6fw6q 6465 4 dismissed dismiss VBN cord-006870-f5w6fw6q 6465 5 as as IN cord-006870-f5w6fw6q 6465 6 sympathetic sympathetic JJ cord-006870-f5w6fw6q 6465 7 storming storming NN cord-006870-f5w6fw6q 6465 8 vs vs IN cord-006870-f5w6fw6q 6465 9 seizures seizure NNS cord-006870-f5w6fw6q 6465 10 as as IN cord-006870-f5w6fw6q 6465 11 she -PRON- PRP cord-006870-f5w6fw6q 6465 12 will will MD cord-006870-f5w6fw6q 6465 13 come come VB cord-006870-f5w6fw6q 6465 14 out out IN cord-006870-f5w6fw6q 6465 15 of of IN cord-006870-f5w6fw6q 6465 16 those those DT cord-006870-f5w6fw6q 6465 17 to to IN cord-006870-f5w6fw6q 6465 18 her -PRON- PRP$ cord-006870-f5w6fw6q 6465 19 baseline baseline NN cord-006870-f5w6fw6q 6465 20 ( ( -LRB- cord-006870-f5w6fw6q 6465 21 awake awake JJ cord-006870-f5w6fw6q 6465 22 with with IN cord-006870-f5w6fw6q 6465 23 mild mild JJ cord-006870-f5w6fw6q 6465 24 left left JJ cord-006870-f5w6fw6q 6465 25 sided sided JJ cord-006870-f5w6fw6q 6465 26 weakness weakness NN cord-006870-f5w6fw6q 6465 27 ) ) -RRB- cord-006870-f5w6fw6q 6465 28 many many JJ cord-006870-f5w6fw6q 6465 29 times time NNS cord-006870-f5w6fw6q 6465 30 without without IN cord-006870-f5w6fw6q 6465 31 therapy therapy NN cord-006870-f5w6fw6q 6465 32 . . . cord-006870-f5w6fw6q 6466 1 She -PRON- PRP cord-006870-f5w6fw6q 6466 2 eventually eventually RB cord-006870-f5w6fw6q 6466 3 required require VBD cord-006870-f5w6fw6q 6466 4 a a DT cord-006870-f5w6fw6q 6466 5 hemicraniectomy hemicraniectomy NN cord-006870-f5w6fw6q 6466 6 two two CD cord-006870-f5w6fw6q 6466 7 weeks week NNS cord-006870-f5w6fw6q 6466 8 after after IN cord-006870-f5w6fw6q 6466 9 presentation presentation NN cord-006870-f5w6fw6q 6466 10 . . . cord-006870-f5w6fw6q 6467 1 Conclusions conclusion NNS cord-006870-f5w6fw6q 6467 2 solated solate VBD cord-006870-f5w6fw6q 6467 3 emotional emotional JJ cord-006870-f5w6fw6q 6467 4 facial facial JJ cord-006870-f5w6fw6q 6467 5 palsy palsy NN cord-006870-f5w6fw6q 6467 6 can can MD cord-006870-f5w6fw6q 6467 7 be be VB cord-006870-f5w6fw6q 6467 8 the the DT cord-006870-f5w6fw6q 6467 9 presenting present VBG cord-006870-f5w6fw6q 6467 10 sign sign NN cord-006870-f5w6fw6q 6467 11 after after IN cord-006870-f5w6fw6q 6467 12 ICH ICH NNP cord-006870-f5w6fw6q 6467 13 when when WRB cord-006870-f5w6fw6q 6467 14 the the DT cord-006870-f5w6fw6q 6467 15 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6467 16 involves involve VBZ cord-006870-f5w6fw6q 6467 17 the the DT cord-006870-f5w6fw6q 6467 18 contralateral contralateral JJ cord-006870-f5w6fw6q 6467 19 thalamus thalamus NN cord-006870-f5w6fw6q 6467 20 , , , cord-006870-f5w6fw6q 6467 21 of of IN cord-006870-f5w6fw6q 6467 22 the the DT cord-006870-f5w6fw6q 6467 23 striato striato JJ cord-006870-f5w6fw6q 6467 24 - - HYPH cord-006870-f5w6fw6q 6467 25 capsular capsular NN cord-006870-f5w6fw6q 6467 26 region region NN cord-006870-f5w6fw6q 6467 27 or or CC cord-006870-f5w6fw6q 6467 28 the the DT cord-006870-f5w6fw6q 6467 29 medial medial JJ cord-006870-f5w6fw6q 6467 30 frontal frontal JJ cord-006870-f5w6fw6q 6467 31 lobes lobe NNS cord-006870-f5w6fw6q 6467 32 . . . cord-006870-f5w6fw6q 6468 1 In in IN cord-006870-f5w6fw6q 6468 2 this this DT cord-006870-f5w6fw6q 6468 3 case case NN cord-006870-f5w6fw6q 6468 4 , , , cord-006870-f5w6fw6q 6468 5 transient transient JJ cord-006870-f5w6fw6q 6468 6 ICP ICP NNP cord-006870-f5w6fw6q 6468 7 elevations elevation NNS cord-006870-f5w6fw6q 6468 8 were be VBD cord-006870-f5w6fw6q 6468 9 leading lead VBG cord-006870-f5w6fw6q 6468 10 to to IN cord-006870-f5w6fw6q 6468 11 dilated dilated JJ cord-006870-f5w6fw6q 6468 12 pupils pupil NNS cord-006870-f5w6fw6q 6468 13 , , , cord-006870-f5w6fw6q 6468 14 tachycardia tachycardia NN cord-006870-f5w6fw6q 6468 15 and and CC cord-006870-f5w6fw6q 6468 16 hypertension hypertension NN cord-006870-f5w6fw6q 6468 17 -highlighting -highlighting . cord-006870-f5w6fw6q 6469 1 that that DT cord-006870-f5w6fw6q 6469 2 heart heart NN cord-006870-f5w6fw6q 6469 3 rate rate NN cord-006870-f5w6fw6q 6469 4 changes change NNS cord-006870-f5w6fw6q 6469 5 can can MD cord-006870-f5w6fw6q 6469 6 be be VB cord-006870-f5w6fw6q 6469 7 variable variable JJ cord-006870-f5w6fw6q 6469 8 with with IN cord-006870-f5w6fw6q 6469 9 elevated elevated JJ cord-006870-f5w6fw6q 6469 10 ICPs icp NNS cord-006870-f5w6fw6q 6469 11 and and CC cord-006870-f5w6fw6q 6469 12 that that IN cord-006870-f5w6fw6q 6469 13 in in IN cord-006870-f5w6fw6q 6469 14 young young JJ cord-006870-f5w6fw6q 6469 15 patients patient NNS cord-006870-f5w6fw6q 6469 16 , , , cord-006870-f5w6fw6q 6469 17 brain brain NN cord-006870-f5w6fw6q 6469 18 herniation herniation NN cord-006870-f5w6fw6q 6469 19 episodes episode NNS cord-006870-f5w6fw6q 6469 20 can can MD cord-006870-f5w6fw6q 6469 21 be be VB cord-006870-f5w6fw6q 6469 22 self self NN cord-006870-f5w6fw6q 6469 23 - - HYPH cord-006870-f5w6fw6q 6469 24 resolved resolve VBN cord-006870-f5w6fw6q 6469 25 with with IN cord-006870-f5w6fw6q 6469 26 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 6469 27 . . . cord-006870-f5w6fw6q 6470 1 18 18 CD cord-006870-f5w6fw6q 6470 2 yo yo UH cord-006870-f5w6fw6q 6470 3 female female JJ cord-006870-f5w6fw6q 6470 4 with with IN cord-006870-f5w6fw6q 6470 5 no no DT cord-006870-f5w6fw6q 6470 6 PMH pmh NN cord-006870-f5w6fw6q 6470 7 developed develop VBN cord-006870-f5w6fw6q 6470 8 fever fever NN cord-006870-f5w6fw6q 6470 9 , , , cord-006870-f5w6fw6q 6470 10 headache headache NN cord-006870-f5w6fw6q 6470 11 , , , cord-006870-f5w6fw6q 6470 12 and and CC cord-006870-f5w6fw6q 6470 13 neck neck NN cord-006870-f5w6fw6q 6470 14 pain pain NN cord-006870-f5w6fw6q 6470 15 . . . cord-006870-f5w6fw6q 6471 1 She -PRON- PRP cord-006870-f5w6fw6q 6471 2 presented present VBD cord-006870-f5w6fw6q 6471 3 to to IN cord-006870-f5w6fw6q 6471 4 outside outside JJ cord-006870-f5w6fw6q 6471 5 hospital hospital NN cord-006870-f5w6fw6q 6471 6 day day NN cord-006870-f5w6fw6q 6471 7 2 2 CD cord-006870-f5w6fw6q 6471 8 after after IN cord-006870-f5w6fw6q 6471 9 CT CT NNP cord-006870-f5w6fw6q 6471 10 head head NN cord-006870-f5w6fw6q 6471 11 was be VBD cord-006870-f5w6fw6q 6471 12 negative negative JJ cord-006870-f5w6fw6q 6471 13 , , , cord-006870-f5w6fw6q 6471 14 patient patient JJ cord-006870-f5w6fw6q 6471 15 was be VBD cord-006870-f5w6fw6q 6471 16 discharged discharge VBN cord-006870-f5w6fw6q 6471 17 . . . cord-006870-f5w6fw6q 6472 1 Symptoms symptom NNS cord-006870-f5w6fw6q 6472 2 did do VBD cord-006870-f5w6fw6q 6472 3 not not RB cord-006870-f5w6fw6q 6472 4 improve improve VB cord-006870-f5w6fw6q 6472 5 and and CC cord-006870-f5w6fw6q 6472 6 she -PRON- PRP cord-006870-f5w6fw6q 6472 7 went go VBD cord-006870-f5w6fw6q 6472 8 to to IN cord-006870-f5w6fw6q 6472 9 her -PRON- PRP$ cord-006870-f5w6fw6q 6472 10 PCP PCP NNP cord-006870-f5w6fw6q 6472 11 on on IN cord-006870-f5w6fw6q 6472 12 day day NN cord-006870-f5w6fw6q 6472 13 4 4 CD cord-006870-f5w6fw6q 6472 14 and and CC cord-006870-f5w6fw6q 6472 15 was be VBD cord-006870-f5w6fw6q 6472 16 instructed instruct VBN cord-006870-f5w6fw6q 6472 17 to to TO cord-006870-f5w6fw6q 6472 18 go go VB cord-006870-f5w6fw6q 6472 19 to to IN cord-006870-f5w6fw6q 6472 20 the the DT cord-006870-f5w6fw6q 6472 21 ED ED NNP cord-006870-f5w6fw6q 6472 22 . . . cord-006870-f5w6fw6q 6473 1 She -PRON- PRP cord-006870-f5w6fw6q 6473 2 presented present VBD cord-006870-f5w6fw6q 6473 3 to to IN cord-006870-f5w6fw6q 6473 4 OSH OSH NNP cord-006870-f5w6fw6q 6473 5 and and CC cord-006870-f5w6fw6q 6473 6 underwent undergo VBD cord-006870-f5w6fw6q 6473 7 a a DT cord-006870-f5w6fw6q 6473 8 LP lp NN cord-006870-f5w6fw6q 6473 9 that that WDT cord-006870-f5w6fw6q 6473 10 was be VBD cord-006870-f5w6fw6q 6473 11 indicative indicative JJ cord-006870-f5w6fw6q 6473 12 of of IN cord-006870-f5w6fw6q 6473 13 viral viral JJ cord-006870-f5w6fw6q 6473 14 meningitis meningitis NN cord-006870-f5w6fw6q 6473 15 with with IN cord-006870-f5w6fw6q 6473 16 WBC WBC NNP cord-006870-f5w6fw6q 6473 17 357 357 CD cord-006870-f5w6fw6q 6473 18 cells cell NNS cord-006870-f5w6fw6q 6473 19 / / SYM cord-006870-f5w6fw6q 6473 20 mm3 mm3 NNS cord-006870-f5w6fw6q 6473 21 and and CC cord-006870-f5w6fw6q 6473 22 protein protein NN cord-006870-f5w6fw6q 6473 23 215 215 CD cord-006870-f5w6fw6q 6473 24 mg mg NNP cord-006870-f5w6fw6q 6473 25 / / SYM cord-006870-f5w6fw6q 6473 26 dL. dL. NNP cord-006870-f5w6fw6q 6473 27 Patient Patient NNP cord-006870-f5w6fw6q 6473 28 admitted admit VBD cord-006870-f5w6fw6q 6473 29 and and CC cord-006870-f5w6fw6q 6473 30 treated treat VBN cord-006870-f5w6fw6q 6473 31 with with IN cord-006870-f5w6fw6q 6473 32 Acyclovir Acyclovir NNP cord-006870-f5w6fw6q 6473 33 . . . cord-006870-f5w6fw6q 6474 1 On on IN cord-006870-f5w6fw6q 6474 2 day day NN cord-006870-f5w6fw6q 6474 3 6 6 CD cord-006870-f5w6fw6q 6474 4 , , , cord-006870-f5w6fw6q 6474 5 she -PRON- PRP cord-006870-f5w6fw6q 6474 6 developed develop VBD cord-006870-f5w6fw6q 6474 7 generalized generalized JJ cord-006870-f5w6fw6q 6474 8 body body NN cord-006870-f5w6fw6q 6474 9 aches ache NNS cord-006870-f5w6fw6q 6474 10 . . . cord-006870-f5w6fw6q 6475 1 On on IN cord-006870-f5w6fw6q 6475 2 day day NN cord-006870-f5w6fw6q 6475 3 8 8 CD cord-006870-f5w6fw6q 6475 4 , , , cord-006870-f5w6fw6q 6475 5 she -PRON- PRP cord-006870-f5w6fw6q 6475 6 was be VBD cord-006870-f5w6fw6q 6475 7 trying try VBG cord-006870-f5w6fw6q 6475 8 to to TO cord-006870-f5w6fw6q 6475 9 stand stand VB cord-006870-f5w6fw6q 6475 10 with with IN cord-006870-f5w6fw6q 6475 11 assistance assistance NN cord-006870-f5w6fw6q 6475 12 and and CC cord-006870-f5w6fw6q 6475 13 she -PRON- PRP cord-006870-f5w6fw6q 6475 14 became become VBD cord-006870-f5w6fw6q 6475 15 rigid rigid JJ cord-006870-f5w6fw6q 6475 16 . . . cord-006870-f5w6fw6q 6476 1 Parents parent NNS cord-006870-f5w6fw6q 6476 2 report report VBP cord-006870-f5w6fw6q 6476 3 a a DT cord-006870-f5w6fw6q 6476 4 total total NN cord-006870-f5w6fw6q 6476 5 of of IN cord-006870-f5w6fw6q 6476 6 4 4 CD cord-006870-f5w6fw6q 6476 7 seizures seizure NNS cord-006870-f5w6fw6q 6476 8 and and CC cord-006870-f5w6fw6q 6476 9 was be VBD cord-006870-f5w6fw6q 6476 10 intubated intubate VBN cord-006870-f5w6fw6q 6476 11 for for IN cord-006870-f5w6fw6q 6476 12 airway airway NN cord-006870-f5w6fw6q 6476 13 protection protection NN cord-006870-f5w6fw6q 6476 14 . . . cord-006870-f5w6fw6q 6477 1 She -PRON- PRP cord-006870-f5w6fw6q 6477 2 underwent undergo VBD cord-006870-f5w6fw6q 6477 3 another another DT cord-006870-f5w6fw6q 6477 4 LP LP NNP cord-006870-f5w6fw6q 6477 5 on on IN cord-006870-f5w6fw6q 6477 6 day day NN cord-006870-f5w6fw6q 6477 7 8 8 CD cord-006870-f5w6fw6q 6477 8 with with IN cord-006870-f5w6fw6q 6477 9 an an DT cord-006870-f5w6fw6q 6477 10 opening opening JJ cord-006870-f5w6fw6q 6477 11 pressure pressure NN cord-006870-f5w6fw6q 6477 12 of of IN cord-006870-f5w6fw6q 6477 13 55 55 CD cord-006870-f5w6fw6q 6477 14 cm cm NNS cord-006870-f5w6fw6q 6478 1 H2O. H2O. NNP cord-006870-f5w6fw6q 6478 2 CSF CSF NNP cord-006870-f5w6fw6q 6478 3 was be VBD cord-006870-f5w6fw6q 6478 4 sent send VBN cord-006870-f5w6fw6q 6478 5 for for IN cord-006870-f5w6fw6q 6478 6 paraneoplastic paraneoplastic JJ cord-006870-f5w6fw6q 6478 7 panel panel NN cord-006870-f5w6fw6q 6478 8 . . . cord-006870-f5w6fw6q 6479 1 CSF csf NN cord-006870-f5w6fw6q 6479 2 analyses analysis NNS cord-006870-f5w6fw6q 6479 3 and and CC cord-006870-f5w6fw6q 6479 4 blood blood NN cord-006870-f5w6fw6q 6479 5 cultures culture NNS cord-006870-f5w6fw6q 6479 6 were be VBD cord-006870-f5w6fw6q 6479 7 negative negative JJ cord-006870-f5w6fw6q 6479 8 . . . cord-006870-f5w6fw6q 6480 1 EVD EVD NNP cord-006870-f5w6fw6q 6480 2 placed place VBD cord-006870-f5w6fw6q 6480 3 for for IN cord-006870-f5w6fw6q 6480 4 ICP ICP NNP cord-006870-f5w6fw6q 6480 5 pressures pressure NNS cord-006870-f5w6fw6q 6480 6 of of IN cord-006870-f5w6fw6q 6480 7 30 30 CD cord-006870-f5w6fw6q 6480 8 - - SYM cord-006870-f5w6fw6q 6480 9 34 34 CD cord-006870-f5w6fw6q 6480 10 cm cm NN cord-006870-f5w6fw6q 6480 11 H2O. H2O. NNP cord-006870-f5w6fw6q 6480 12 History history NN cord-006870-f5w6fw6q 6480 13 obtained obtain VBN cord-006870-f5w6fw6q 6480 14 from from IN cord-006870-f5w6fw6q 6480 15 mother mother NN cord-006870-f5w6fw6q 6480 16 and and CC cord-006870-f5w6fw6q 6480 17 father father NN cord-006870-f5w6fw6q 6480 18 who who WP cord-006870-f5w6fw6q 6480 19 reported report VBD cord-006870-f5w6fw6q 6480 20 the the DT cord-006870-f5w6fw6q 6480 21 patient patient NN cord-006870-f5w6fw6q 6480 22 had have VBD cord-006870-f5w6fw6q 6480 23 been be VBN cord-006870-f5w6fw6q 6480 24 hiking hike VBG cord-006870-f5w6fw6q 6480 25 2 2 CD cord-006870-f5w6fw6q 6480 26 weeks week NNS cord-006870-f5w6fw6q 6480 27 prior prior RB cord-006870-f5w6fw6q 6480 28 . . . cord-006870-f5w6fw6q 6481 1 Results result VBZ cord-006870-f5w6fw6q 6481 2 MRI MRI NNP cord-006870-f5w6fw6q 6481 3 brain brain NN cord-006870-f5w6fw6q 6481 4 showed show VBD cord-006870-f5w6fw6q 6481 5 meningeal meningeal JJ cord-006870-f5w6fw6q 6481 6 enhancement enhancement NN cord-006870-f5w6fw6q 6481 7 scattered scatter VBN cord-006870-f5w6fw6q 6481 8 throughout throughout IN cord-006870-f5w6fw6q 6481 9 the the DT cord-006870-f5w6fw6q 6481 10 supratentorial supratentorial NN cord-006870-f5w6fw6q 6481 11 and and CC cord-006870-f5w6fw6q 6481 12 infratentorial infratentorial JJ cord-006870-f5w6fw6q 6481 13 brain brain NN cord-006870-f5w6fw6q 6481 14 and and CC cord-006870-f5w6fw6q 6481 15 most most RBS cord-006870-f5w6fw6q 6481 16 compatible compatible JJ cord-006870-f5w6fw6q 6481 17 with with IN cord-006870-f5w6fw6q 6481 18 inflammatory inflammatory JJ cord-006870-f5w6fw6q 6481 19 sequela sequela NN cord-006870-f5w6fw6q 6481 20 of of IN cord-006870-f5w6fw6q 6481 21 meningitis meningitis NN cord-006870-f5w6fw6q 6481 22 . . . cord-006870-f5w6fw6q 6482 1 Patient Patient NNP cord-006870-f5w6fw6q 6482 2 continued continue VBD cord-006870-f5w6fw6q 6482 3 on on IN cord-006870-f5w6fw6q 6482 4 keppra keppra NNP cord-006870-f5w6fw6q 6482 5 , , , cord-006870-f5w6fw6q 6482 6 high high JJ cord-006870-f5w6fw6q 6482 7 dose dose NN cord-006870-f5w6fw6q 6482 8 steroids steroid NNS cord-006870-f5w6fw6q 6482 9 , , , cord-006870-f5w6fw6q 6482 10 antibiotic antibiotic JJ cord-006870-f5w6fw6q 6482 11 , , , cord-006870-f5w6fw6q 6482 12 antiviral antiviral JJ cord-006870-f5w6fw6q 6482 13 , , , cord-006870-f5w6fw6q 6482 14 antifungal antifungal JJ cord-006870-f5w6fw6q 6482 15 therapy therapy NN cord-006870-f5w6fw6q 6482 16 until until IN cord-006870-f5w6fw6q 6482 17 cultures culture NNS cord-006870-f5w6fw6q 6482 18 resulted result VBD cord-006870-f5w6fw6q 6482 19 . . . cord-006870-f5w6fw6q 6483 1 Additional additional JJ cord-006870-f5w6fw6q 6483 2 treatments treatment NNS cord-006870-f5w6fw6q 6483 3 included include VBD cord-006870-f5w6fw6q 6483 4 IVIG IVIG NNP cord-006870-f5w6fw6q 6483 5 therapy therapy NN cord-006870-f5w6fw6q 6483 6 followed follow VBN cord-006870-f5w6fw6q 6483 7 by by IN cord-006870-f5w6fw6q 6483 8 plasmapheresis plasmapheresis NN cord-006870-f5w6fw6q 6483 9 , , , cord-006870-f5w6fw6q 6483 10 and and CC cord-006870-f5w6fw6q 6483 11 finally finally RB cord-006870-f5w6fw6q 6483 12 Rituximab Rituximab NNPS cord-006870-f5w6fw6q 6483 13 . . . cord-006870-f5w6fw6q 6484 1 Continued continue VBN cord-006870-f5w6fw6q 6484 2 workup workup JJ cord-006870-f5w6fw6q 6484 3 with with IN cord-006870-f5w6fw6q 6484 4 brain brain NN cord-006870-f5w6fw6q 6484 5 biopsy biopsy NN cord-006870-f5w6fw6q 6484 6 showed show VBD cord-006870-f5w6fw6q 6484 7 demyelinating demyelinate VBG cord-006870-f5w6fw6q 6484 8 process process NN cord-006870-f5w6fw6q 6484 9 and and CC cord-006870-f5w6fw6q 6484 10 possible possible JJ cord-006870-f5w6fw6q 6484 11 necrotizing necrotize VBG cord-006870-f5w6fw6q 6484 12 encephalitis encephalitis RB cord-006870-f5w6fw6q 6484 13 . . . cord-006870-f5w6fw6q 6485 1 MRI MRI NNP cord-006870-f5w6fw6q 6486 1 four four CD cord-006870-f5w6fw6q 6486 2 weeks week NNS cord-006870-f5w6fw6q 6486 3 after after IN cord-006870-f5w6fw6q 6486 4 initial initial JJ cord-006870-f5w6fw6q 6486 5 presentation presentation NN cord-006870-f5w6fw6q 6486 6 showed show VBD cord-006870-f5w6fw6q 6486 7 white white JJ cord-006870-f5w6fw6q 6486 8 matter matter NN cord-006870-f5w6fw6q 6486 9 demyelination demyelination NN cord-006870-f5w6fw6q 6486 10 and and CC cord-006870-f5w6fw6q 6486 11 deep deep JJ cord-006870-f5w6fw6q 6486 12 gray gray JJ cord-006870-f5w6fw6q 6486 13 nuclei nucleus NNS cord-006870-f5w6fw6q 6486 14 lesions lesion NNS cord-006870-f5w6fw6q 6486 15 consistent consistent JJ cord-006870-f5w6fw6q 6486 16 with with IN cord-006870-f5w6fw6q 6486 17 ADEM ADEM NNP cord-006870-f5w6fw6q 6486 18 . . . cord-006870-f5w6fw6q 6487 1 FOUR four CD cord-006870-f5w6fw6q 6487 2 score score NN cord-006870-f5w6fw6q 6487 3 of of IN cord-006870-f5w6fw6q 6487 4 0 0 CD cord-006870-f5w6fw6q 6487 5 on on IN cord-006870-f5w6fw6q 6487 6 admission admission NN cord-006870-f5w6fw6q 6487 7 improved improve VBN cord-006870-f5w6fw6q 6487 8 to to IN cord-006870-f5w6fw6q 6487 9 11 11 CD cord-006870-f5w6fw6q 6487 10 ( ( -LRB- cord-006870-f5w6fw6q 6487 11 E3 E3 NNP cord-006870-f5w6fw6q 6487 12 , , , cord-006870-f5w6fw6q 6487 13 M0 M0 NNP cord-006870-f5w6fw6q 6487 14 , , , cord-006870-f5w6fw6q 6487 15 B4 B4 NNP cord-006870-f5w6fw6q 6487 16 , , , cord-006870-f5w6fw6q 6487 17 R4 R4 NNP cord-006870-f5w6fw6q 6487 18 ) ) -RRB- cord-006870-f5w6fw6q 6487 19 5 5 CD cord-006870-f5w6fw6q 6487 20 weeks week NNS cord-006870-f5w6fw6q 6487 21 after after IN cord-006870-f5w6fw6q 6487 22 patient patient NN cord-006870-f5w6fw6q 6487 23 presented present VBN cord-006870-f5w6fw6q 6487 24 from from IN cord-006870-f5w6fw6q 6487 25 OSH OSH NNP cord-006870-f5w6fw6q 6487 26 . . . cord-006870-f5w6fw6q 6488 1 Diagnosis diagnosis NN cord-006870-f5w6fw6q 6488 2 of of IN cord-006870-f5w6fw6q 6488 3 ADEM ADEM NNP cord-006870-f5w6fw6q 6488 4 vs vs IN cord-006870-f5w6fw6q 6488 5 MS MS NNP cord-006870-f5w6fw6q 6488 6 variant variant NN cord-006870-f5w6fw6q 6488 7 made make VBD cord-006870-f5w6fw6q 6488 8 based base VBN cord-006870-f5w6fw6q 6488 9 on on IN cord-006870-f5w6fw6q 6488 10 the the DT cord-006870-f5w6fw6q 6488 11 above above JJ cord-006870-f5w6fw6q 6488 12 data datum NNS cord-006870-f5w6fw6q 6488 13 . . . cord-006870-f5w6fw6q 6489 1 Case case NN cord-006870-f5w6fw6q 6489 2 provides provide VBZ cord-006870-f5w6fw6q 6489 3 information information NN cord-006870-f5w6fw6q 6489 4 for for IN cord-006870-f5w6fw6q 6489 5 the the DT cord-006870-f5w6fw6q 6489 6 clinician clinician NN cord-006870-f5w6fw6q 6489 7 diagnosing diagnose VBG cord-006870-f5w6fw6q 6489 8 and and CC cord-006870-f5w6fw6q 6489 9 treating treat VBG cord-006870-f5w6fw6q 6489 10 ADEM ADEM NNP cord-006870-f5w6fw6q 6489 11 . . . cord-006870-f5w6fw6q 6490 1 Potential potential NN cord-006870-f5w6fw6q 6490 2 for for IN cord-006870-f5w6fw6q 6490 3 further further JJ cord-006870-f5w6fw6q 6490 4 studies study NNS cord-006870-f5w6fw6q 6490 5 with with IN cord-006870-f5w6fw6q 6490 6 treatments treatment NNS cord-006870-f5w6fw6q 6490 7 described describe VBN cord-006870-f5w6fw6q 6490 8 above above IN cord-006870-f5w6fw6q 6490 9 and and CC cord-006870-f5w6fw6q 6490 10 their -PRON- PRP$ cord-006870-f5w6fw6q 6490 11 effect effect NN cord-006870-f5w6fw6q 6490 12 on on IN cord-006870-f5w6fw6q 6490 13 meaningful meaningful JJ cord-006870-f5w6fw6q 6490 14 neurological neurological JJ cord-006870-f5w6fw6q 6490 15 outcomes outcome NNS cord-006870-f5w6fw6q 6490 16 . . . cord-006870-f5w6fw6q 6491 1 Dengue dengue NN cord-006870-f5w6fw6q 6491 2 is be VBZ cord-006870-f5w6fw6q 6491 3 a a DT cord-006870-f5w6fw6q 6491 4 flaviviruses flavivirus NNS cord-006870-f5w6fw6q 6491 5 transmitted transmit VBN cord-006870-f5w6fw6q 6491 6 via via IN cord-006870-f5w6fw6q 6491 7 mosquitos mosquitos NN cord-006870-f5w6fw6q 6491 8 and and CC cord-006870-f5w6fw6q 6491 9 prevalent prevalent JJ cord-006870-f5w6fw6q 6491 10 in in IN cord-006870-f5w6fw6q 6491 11 South South NNP cord-006870-f5w6fw6q 6491 12 East East NNP cord-006870-f5w6fw6q 6491 13 Asia Asia NNP cord-006870-f5w6fw6q 6491 14 . . . cord-006870-f5w6fw6q 6492 1 Neurological neurological JJ cord-006870-f5w6fw6q 6492 2 complications complication NNS cord-006870-f5w6fw6q 6492 3 are be VBP cord-006870-f5w6fw6q 6492 4 rare rare JJ cord-006870-f5w6fw6q 6492 5 but but CC cord-006870-f5w6fw6q 6492 6 can can MD cord-006870-f5w6fw6q 6492 7 involve involve VB cord-006870-f5w6fw6q 6492 8 encephalitis encephalitis RB cord-006870-f5w6fw6q 6492 9 , , , cord-006870-f5w6fw6q 6492 10 myelitis myelitis NNP cord-006870-f5w6fw6q 6492 11 , , , cord-006870-f5w6fw6q 6492 12 neuromuscular neuromuscular JJ cord-006870-f5w6fw6q 6492 13 dysfunction dysfunction NN cord-006870-f5w6fw6q 6492 14 and and CC cord-006870-f5w6fw6q 6492 15 neuroophthalmological neuroophthalmological JJ cord-006870-f5w6fw6q 6492 16 problems problem NNS cord-006870-f5w6fw6q 6492 17 . . . cord-006870-f5w6fw6q 6493 1 We -PRON- PRP cord-006870-f5w6fw6q 6493 2 describe describe VBP cord-006870-f5w6fw6q 6493 3 an an DT cord-006870-f5w6fw6q 6493 4 interesting interesting JJ cord-006870-f5w6fw6q 6493 5 case case NN cord-006870-f5w6fw6q 6493 6 of of IN cord-006870-f5w6fw6q 6493 7 dengue dengue NN cord-006870-f5w6fw6q 6493 8 encephalomyelitis encephalomyelitis NN cord-006870-f5w6fw6q 6493 9 . . . cord-006870-f5w6fw6q 6494 1 Retrospective retrospective JJ cord-006870-f5w6fw6q 6494 2 review review NN cord-006870-f5w6fw6q 6494 3 of of IN cord-006870-f5w6fw6q 6494 4 a a DT cord-006870-f5w6fw6q 6494 5 case case NN cord-006870-f5w6fw6q 6494 6 admitted admit VBN cord-006870-f5w6fw6q 6494 7 to to IN cord-006870-f5w6fw6q 6494 8 the the DT cord-006870-f5w6fw6q 6494 9 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 6494 10 Care Care NNP cord-006870-f5w6fw6q 6494 11 Unit Unit NNP cord-006870-f5w6fw6q 6494 12 ( ( -LRB- cord-006870-f5w6fw6q 6494 13 NCCU NCCU NNP cord-006870-f5w6fw6q 6494 14 ) ) -RRB- cord-006870-f5w6fw6q 6494 15 of of IN cord-006870-f5w6fw6q 6494 16 the the DT cord-006870-f5w6fw6q 6494 17 Johns Johns NNP cord-006870-f5w6fw6q 6494 18 Hopkins Hopkins NNP cord-006870-f5w6fw6q 6494 19 Hospital Hospital NNP cord-006870-f5w6fw6q 6494 20 A A NNP cord-006870-f5w6fw6q 6494 21 54 54 CD cord-006870-f5w6fw6q 6494 22 year year NN cord-006870-f5w6fw6q 6494 23 - - HYPH cord-006870-f5w6fw6q 6494 24 old old JJ cord-006870-f5w6fw6q 6494 25 ship ship NN cord-006870-f5w6fw6q 6494 26 Filipino Filipino NNP cord-006870-f5w6fw6q 6494 27 captain captain NN cord-006870-f5w6fw6q 6494 28 with with IN cord-006870-f5w6fw6q 6494 29 no no DT cord-006870-f5w6fw6q 6494 30 significant significant JJ cord-006870-f5w6fw6q 6494 31 past past JJ cord-006870-f5w6fw6q 6494 32 medical medical JJ cord-006870-f5w6fw6q 6494 33 history history NN cord-006870-f5w6fw6q 6494 34 but but CC cord-006870-f5w6fw6q 6494 35 an an DT cord-006870-f5w6fw6q 6494 36 extensive extensive JJ cord-006870-f5w6fw6q 6494 37 exposure exposure NN cord-006870-f5w6fw6q 6494 38 to to IN cord-006870-f5w6fw6q 6494 39 heavy heavy JJ cord-006870-f5w6fw6q 6494 40 metals metal NNS cord-006870-f5w6fw6q 6494 41 , , , cord-006870-f5w6fw6q 6494 42 travel travel VBP cord-006870-f5w6fw6q 6494 43 throughout throughout IN cord-006870-f5w6fw6q 6494 44 the the DT cord-006870-f5w6fw6q 6494 45 Pacific Pacific NNP cord-006870-f5w6fw6q 6494 46 , , , cord-006870-f5w6fw6q 6494 47 who who WP cord-006870-f5w6fw6q 6494 48 presented present VBD cord-006870-f5w6fw6q 6494 49 with with IN cord-006870-f5w6fw6q 6494 50 progressively progressively RB cord-006870-f5w6fw6q 6494 51 worsening worsen VBG cord-006870-f5w6fw6q 6494 52 fevers fever NNS cord-006870-f5w6fw6q 6494 53 , , , cord-006870-f5w6fw6q 6494 54 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6494 55 , , , cord-006870-f5w6fw6q 6494 56 urinary urinary JJ cord-006870-f5w6fw6q 6494 57 retention retention NN cord-006870-f5w6fw6q 6494 58 and and CC cord-006870-f5w6fw6q 6494 59 tremors tremor NNS cord-006870-f5w6fw6q 6494 60 . . . cord-006870-f5w6fw6q 6495 1 He -PRON- PRP cord-006870-f5w6fw6q 6495 2 was be VBD cord-006870-f5w6fw6q 6495 3 transporting transport VBG cord-006870-f5w6fw6q 6495 4 iron iron NN cord-006870-f5w6fw6q 6495 5 ore ore NN cord-006870-f5w6fw6q 6495 6 and and CC cord-006870-f5w6fw6q 6495 7 other other JJ cord-006870-f5w6fw6q 6495 8 metals metal NNS cord-006870-f5w6fw6q 6495 9 in in IN cord-006870-f5w6fw6q 6495 10 a a DT cord-006870-f5w6fw6q 6495 11 cargo cargo NN cord-006870-f5w6fw6q 6495 12 ship ship NN cord-006870-f5w6fw6q 6495 13 from from IN cord-006870-f5w6fw6q 6495 14 Russia Russia NNP cord-006870-f5w6fw6q 6495 15 through through IN cord-006870-f5w6fw6q 6495 16 South South NNP cord-006870-f5w6fw6q 6495 17 - - HYPH cord-006870-f5w6fw6q 6495 18 East East NNP cord-006870-f5w6fw6q 6495 19 Asia Asia NNP cord-006870-f5w6fw6q 6495 20 through through RB cord-006870-f5w6fw6q 6495 21 to to IN cord-006870-f5w6fw6q 6495 22 Bermuda Bermuda NNP cord-006870-f5w6fw6q 6495 23 . . . cord-006870-f5w6fw6q 6496 1 While while IN cord-006870-f5w6fw6q 6496 2 passing pass VBG cord-006870-f5w6fw6q 6496 3 through through IN cord-006870-f5w6fw6q 6496 4 the the DT cord-006870-f5w6fw6q 6496 5 Pacific Pacific NNP cord-006870-f5w6fw6q 6496 6 , , , cord-006870-f5w6fw6q 6496 7 he -PRON- PRP cord-006870-f5w6fw6q 6496 8 began begin VBD cord-006870-f5w6fw6q 6496 9 to to TO cord-006870-f5w6fw6q 6496 10 experience experience VB cord-006870-f5w6fw6q 6496 11 malaise malaise NN cord-006870-f5w6fw6q 6496 12 , , , cord-006870-f5w6fw6q 6496 13 myalgia myalgia NN cord-006870-f5w6fw6q 6496 14 , , , cord-006870-f5w6fw6q 6496 15 and and CC cord-006870-f5w6fw6q 6496 16 fever fever NN cord-006870-f5w6fw6q 6496 17 . . . cord-006870-f5w6fw6q 6497 1 He -PRON- PRP cord-006870-f5w6fw6q 6497 2 was be VBD cord-006870-f5w6fw6q 6497 3 treated treat VBN cord-006870-f5w6fw6q 6497 4 with with IN cord-006870-f5w6fw6q 6497 5 Amoxicillin Amoxicillin NNP cord-006870-f5w6fw6q 6497 6 but but CC cord-006870-f5w6fw6q 6497 7 became become VBD cord-006870-f5w6fw6q 6497 8 worse bad JJR cord-006870-f5w6fw6q 6497 9 , , , cord-006870-f5w6fw6q 6497 10 developing develop VBG cord-006870-f5w6fw6q 6497 11 urinary urinary JJ cord-006870-f5w6fw6q 6497 12 retention retention NN cord-006870-f5w6fw6q 6497 13 , , , cord-006870-f5w6fw6q 6497 14 periods period NNS cord-006870-f5w6fw6q 6497 15 of of IN cord-006870-f5w6fw6q 6497 16 confusion confusion NN cord-006870-f5w6fw6q 6497 17 , , , cord-006870-f5w6fw6q 6497 18 and and CC cord-006870-f5w6fw6q 6497 19 word word NN cord-006870-f5w6fw6q 6497 20 finding finding NN cord-006870-f5w6fw6q 6497 21 difficulties difficulty NNS cord-006870-f5w6fw6q 6497 22 . . . cord-006870-f5w6fw6q 6498 1 He -PRON- PRP cord-006870-f5w6fw6q 6498 2 was be VBD cord-006870-f5w6fw6q 6498 3 initially initially RB cord-006870-f5w6fw6q 6498 4 hospitalized hospitalize VBN cord-006870-f5w6fw6q 6498 5 in in IN cord-006870-f5w6fw6q 6498 6 Bermuda Bermuda NNP cord-006870-f5w6fw6q 6498 7 and and CC cord-006870-f5w6fw6q 6498 8 then then RB cord-006870-f5w6fw6q 6498 9 transferred transfer VBD cord-006870-f5w6fw6q 6498 10 to to IN cord-006870-f5w6fw6q 6498 11 our -PRON- PRP$ cord-006870-f5w6fw6q 6498 12 hospital hospital NN cord-006870-f5w6fw6q 6498 13 for for IN cord-006870-f5w6fw6q 6498 14 further further JJ cord-006870-f5w6fw6q 6498 15 workup workup NN cord-006870-f5w6fw6q 6498 16 . . . cord-006870-f5w6fw6q 6499 1 Given give VBN cord-006870-f5w6fw6q 6499 2 his -PRON- PRP$ cord-006870-f5w6fw6q 6499 3 rapid rapid JJ cord-006870-f5w6fw6q 6499 4 deterioration deterioration NN cord-006870-f5w6fw6q 6499 5 , , , cord-006870-f5w6fw6q 6499 6 he -PRON- PRP cord-006870-f5w6fw6q 6499 7 was be VBD cord-006870-f5w6fw6q 6499 8 initially initially RB cord-006870-f5w6fw6q 6499 9 in in IN cord-006870-f5w6fw6q 6499 10 the the DT cord-006870-f5w6fw6q 6499 11 NCCU NCCU NNP cord-006870-f5w6fw6q 6499 12 . . . cord-006870-f5w6fw6q 6500 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6500 2 exam exam NN cord-006870-f5w6fw6q 6500 3 was be VBD cord-006870-f5w6fw6q 6500 4 notable notable JJ cord-006870-f5w6fw6q 6500 5 for for IN cord-006870-f5w6fw6q 6500 6 mild mild JJ cord-006870-f5w6fw6q 6500 7 expressive expressive JJ cord-006870-f5w6fw6q 6500 8 aphasia aphasia NN cord-006870-f5w6fw6q 6500 9 , , , cord-006870-f5w6fw6q 6500 10 paratonias paratonias NNP cord-006870-f5w6fw6q 6500 11 , , , cord-006870-f5w6fw6q 6500 12 right right JJ cord-006870-f5w6fw6q 6500 13 - - HYPH cord-006870-f5w6fw6q 6500 14 sided sided JJ cord-006870-f5w6fw6q 6500 15 weakness weakness NN cord-006870-f5w6fw6q 6500 16 with with IN cord-006870-f5w6fw6q 6500 17 hyper hyper JJ cord-006870-f5w6fw6q 6500 18 - - NN cord-006870-f5w6fw6q 6500 19 reflexia reflexia JJ cord-006870-f5w6fw6q 6500 20 , , , cord-006870-f5w6fw6q 6500 21 and and CC cord-006870-f5w6fw6q 6500 22 a a DT cord-006870-f5w6fw6q 6500 23 low low JJ cord-006870-f5w6fw6q 6500 24 amplitude amplitude NN cord-006870-f5w6fw6q 6500 25 tremor tremor NN cord-006870-f5w6fw6q 6500 26 . . . cord-006870-f5w6fw6q 6501 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6501 2 CSF csf NN cord-006870-f5w6fw6q 6501 3 was be VBD cord-006870-f5w6fw6q 6501 4 notable notable JJ cord-006870-f5w6fw6q 6501 5 for for IN cord-006870-f5w6fw6q 6501 6 lymphocytic lymphocytic JJ cord-006870-f5w6fw6q 6501 7 pleocytosis pleocytosis NNP cord-006870-f5w6fw6q 6501 8 , , , cord-006870-f5w6fw6q 6501 9 elevated elevated JJ cord-006870-f5w6fw6q 6501 10 protein protein NN cord-006870-f5w6fw6q 6501 11 , , , cord-006870-f5w6fw6q 6501 12 low low JJ cord-006870-f5w6fw6q 6501 13 glucose glucose NN cord-006870-f5w6fw6q 6501 14 . . . cord-006870-f5w6fw6q 6502 1 MRI MRI NNP cord-006870-f5w6fw6q 6502 2 Brain Brain NNP cord-006870-f5w6fw6q 6502 3 showed show VBD cord-006870-f5w6fw6q 6502 4 flair flair NN cord-006870-f5w6fw6q 6502 5 hyper hyper NNS cord-006870-f5w6fw6q 6502 6 - - NNS cord-006870-f5w6fw6q 6502 7 intensities intensity NNS cord-006870-f5w6fw6q 6502 8 in in IN cord-006870-f5w6fw6q 6502 9 the the DT cord-006870-f5w6fw6q 6502 10 frontal frontal JJ cord-006870-f5w6fw6q 6502 11 lobes lobe NNS cord-006870-f5w6fw6q 6502 12 , , , cord-006870-f5w6fw6q 6502 13 and and CC cord-006870-f5w6fw6q 6502 14 diffusion diffusion NN cord-006870-f5w6fw6q 6502 15 restrictions restriction NNS cord-006870-f5w6fw6q 6502 16 in in IN cord-006870-f5w6fw6q 6502 17 the the DT cord-006870-f5w6fw6q 6502 18 bilateral bilateral JJ cord-006870-f5w6fw6q 6502 19 basal basal NN cord-006870-f5w6fw6q 6502 20 ganglia ganglion NNS cord-006870-f5w6fw6q 6502 21 and and CC cord-006870-f5w6fw6q 6502 22 thalami thalami NNP cord-006870-f5w6fw6q 6502 23 . . . cord-006870-f5w6fw6q 6503 1 MRI MRI NNP cord-006870-f5w6fw6q 6503 2 spine spine NN cord-006870-f5w6fw6q 6503 3 showed show VBD cord-006870-f5w6fw6q 6503 4 extensive extensive JJ cord-006870-f5w6fw6q 6503 5 flair flair NN cord-006870-f5w6fw6q 6503 6 hyper hyper JJ cord-006870-f5w6fw6q 6503 7 - - HYPH cord-006870-f5w6fw6q 6503 8 intensity intensity NN cord-006870-f5w6fw6q 6503 9 lesions lesion NNS cord-006870-f5w6fw6q 6503 10 . . . cord-006870-f5w6fw6q 6504 1 An an DT cord-006870-f5w6fw6q 6504 2 extensive extensive JJ cord-006870-f5w6fw6q 6504 3 workup workup NN cord-006870-f5w6fw6q 6504 4 evaluated evaluate VBN cord-006870-f5w6fw6q 6504 5 for for IN cord-006870-f5w6fw6q 6504 6 heavy heavy JJ cord-006870-f5w6fw6q 6504 7 metal metal NN cord-006870-f5w6fw6q 6504 8 toxicities toxicity NNS cord-006870-f5w6fw6q 6504 9 , , , cord-006870-f5w6fw6q 6504 10 autoimmune autoimmune JJ cord-006870-f5w6fw6q 6504 11 disorders disorder NNS cord-006870-f5w6fw6q 6504 12 and and CC cord-006870-f5w6fw6q 6504 13 infectious infectious JJ cord-006870-f5w6fw6q 6504 14 workup workup NN cord-006870-f5w6fw6q 6504 15 . . . cord-006870-f5w6fw6q 6505 1 CSF CSF NNP cord-006870-f5w6fw6q 6505 2 analysis analysis NN cord-006870-f5w6fw6q 6505 3 came come VBD cord-006870-f5w6fw6q 6505 4 back back RB cord-006870-f5w6fw6q 6505 5 positive positive JJ cord-006870-f5w6fw6q 6505 6 for for IN cord-006870-f5w6fw6q 6505 7 Dengue Dengue NNP cord-006870-f5w6fw6q 6505 8 IgG igg NN cord-006870-f5w6fw6q 6505 9 and and CC cord-006870-f5w6fw6q 6505 10 IgM IgM NNP cord-006870-f5w6fw6q 6505 11 , , , cord-006870-f5w6fw6q 6505 12 leading lead VBG cord-006870-f5w6fw6q 6505 13 to to IN cord-006870-f5w6fw6q 6505 14 a a DT cord-006870-f5w6fw6q 6505 15 diagnosis diagnosis NN cord-006870-f5w6fw6q 6505 16 of of IN cord-006870-f5w6fw6q 6505 17 acute acute JJ cord-006870-f5w6fw6q 6505 18 Dengue dengue NN cord-006870-f5w6fw6q 6505 19 fever fever NN cord-006870-f5w6fw6q 6505 20 and and CC cord-006870-f5w6fw6q 6505 21 encephalomyelitis encephalomyelitis NN cord-006870-f5w6fw6q 6505 22 . . . cord-006870-f5w6fw6q 6506 1 With with IN cord-006870-f5w6fw6q 6506 2 supportive supportive JJ cord-006870-f5w6fw6q 6506 3 care care NN cord-006870-f5w6fw6q 6506 4 in in IN cord-006870-f5w6fw6q 6506 5 the the DT cord-006870-f5w6fw6q 6506 6 NCCU NCCU NNP cord-006870-f5w6fw6q 6506 7 , , , cord-006870-f5w6fw6q 6506 8 he -PRON- PRP cord-006870-f5w6fw6q 6506 9 improved improve VBD cord-006870-f5w6fw6q 6506 10 considerably considerably RB cord-006870-f5w6fw6q 6506 11 over over IN cord-006870-f5w6fw6q 6506 12 2 2 CD cord-006870-f5w6fw6q 6506 13 - - SYM cord-006870-f5w6fw6q 6506 14 3 3 CD cord-006870-f5w6fw6q 6506 15 weeks week NNS cord-006870-f5w6fw6q 6506 16 and and CC cord-006870-f5w6fw6q 6506 17 was be VBD cord-006870-f5w6fw6q 6506 18 discharged discharge VBN cord-006870-f5w6fw6q 6506 19 home home RB cord-006870-f5w6fw6q 6506 20 to to IN cord-006870-f5w6fw6q 6506 21 the the DT cord-006870-f5w6fw6q 6506 22 Philippines Philippines NNPS cord-006870-f5w6fw6q 6506 23 . . . cord-006870-f5w6fw6q 6507 1 Dengue dengue NN cord-006870-f5w6fw6q 6507 2 encephalomyelitis encephalomyelitis NN cord-006870-f5w6fw6q 6507 3 is be VBZ cord-006870-f5w6fw6q 6507 4 a a DT cord-006870-f5w6fw6q 6507 5 rare rare JJ cord-006870-f5w6fw6q 6507 6 infection infection NN cord-006870-f5w6fw6q 6507 7 but but CC cord-006870-f5w6fw6q 6507 8 should should MD cord-006870-f5w6fw6q 6507 9 be be VB cord-006870-f5w6fw6q 6507 10 considered consider VBN cord-006870-f5w6fw6q 6507 11 in in IN cord-006870-f5w6fw6q 6507 12 patients patient NNS cord-006870-f5w6fw6q 6507 13 living live VBG cord-006870-f5w6fw6q 6507 14 in in IN cord-006870-f5w6fw6q 6507 15 endemic endemic JJ cord-006870-f5w6fw6q 6507 16 areas area NNS cord-006870-f5w6fw6q 6507 17 . . . cord-006870-f5w6fw6q 6508 1 Treatment treatment NN cord-006870-f5w6fw6q 6508 2 includes include VBZ cord-006870-f5w6fw6q 6508 3 supportive supportive JJ cord-006870-f5w6fw6q 6508 4 care care NN cord-006870-f5w6fw6q 6508 5 with with IN cord-006870-f5w6fw6q 6508 6 fluid fluid JJ cord-006870-f5w6fw6q 6508 7 resuscitation resuscitation NN cord-006870-f5w6fw6q 6508 8 , , , cord-006870-f5w6fw6q 6508 9 neurological neurological JJ cord-006870-f5w6fw6q 6508 10 monitoring monitoring NN cord-006870-f5w6fw6q 6508 11 and and CC cord-006870-f5w6fw6q 6508 12 monitoring monitoring NN cord-006870-f5w6fw6q 6508 13 for for IN cord-006870-f5w6fw6q 6508 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6508 15 . . . cord-006870-f5w6fw6q 6509 1 Posterior Posterior NNP cord-006870-f5w6fw6q 6509 2 Reversible Reversible NNP cord-006870-f5w6fw6q 6509 3 Encephalopathy Encephalopathy NNP cord-006870-f5w6fw6q 6509 4 Syndrome Syndrome NNP cord-006870-f5w6fw6q 6509 5 ( ( -LRB- cord-006870-f5w6fw6q 6509 6 PRES PRES NNP cord-006870-f5w6fw6q 6509 7 ) ) -RRB- cord-006870-f5w6fw6q 6509 8 is be VBZ cord-006870-f5w6fw6q 6509 9 known know VBN cord-006870-f5w6fw6q 6509 10 to to TO cord-006870-f5w6fw6q 6509 11 cause cause VB cord-006870-f5w6fw6q 6509 12 altered alter VBN cord-006870-f5w6fw6q 6509 13 mental mental JJ cord-006870-f5w6fw6q 6509 14 status status NN cord-006870-f5w6fw6q 6509 15 and and CC cord-006870-f5w6fw6q 6509 16 leukoencephalopathy leukoencephalopathy NN cord-006870-f5w6fw6q 6509 17 in in IN cord-006870-f5w6fw6q 6509 18 the the DT cord-006870-f5w6fw6q 6509 19 setting set VBG cord-006870-f5w6fw6q 6509 20 hypertensive hypertensive JJ cord-006870-f5w6fw6q 6509 21 emergency emergency NN cord-006870-f5w6fw6q 6509 22 . . . cord-006870-f5w6fw6q 6510 1 We -PRON- PRP cord-006870-f5w6fw6q 6510 2 present present VBP cord-006870-f5w6fw6q 6510 3 a a DT cord-006870-f5w6fw6q 6510 4 novel novel JJ cord-006870-f5w6fw6q 6510 5 case case NN cord-006870-f5w6fw6q 6510 6 of of IN cord-006870-f5w6fw6q 6510 7 severely severely RB cord-006870-f5w6fw6q 6510 8 asymmetric asymmetric JJ cord-006870-f5w6fw6q 6510 9 PRES PRES NNP cord-006870-f5w6fw6q 6510 10 due due IN cord-006870-f5w6fw6q 6510 11 to to IN cord-006870-f5w6fw6q 6510 12 a a DT cord-006870-f5w6fw6q 6510 13 concurrent concurrent JJ cord-006870-f5w6fw6q 6510 14 right right JJ cord-006870-f5w6fw6q 6510 15 transverse transverse JJ cord-006870-f5w6fw6q 6510 16 sinus sinus NN cord-006870-f5w6fw6q 6510 17 dural dural JJ cord-006870-f5w6fw6q 6510 18 arteriovenous arteriovenous JJ cord-006870-f5w6fw6q 6510 19 fistula fistula NN cord-006870-f5w6fw6q 6510 20 ( ( -LRB- cord-006870-f5w6fw6q 6510 21 dAVF dAVF NNP cord-006870-f5w6fw6q 6510 22 ) ) -RRB- cord-006870-f5w6fw6q 6510 23 . . . cord-006870-f5w6fw6q 6511 1 A a DT cord-006870-f5w6fw6q 6511 2 53 53 CD cord-006870-f5w6fw6q 6511 3 year year NN cord-006870-f5w6fw6q 6511 4 - - HYPH cord-006870-f5w6fw6q 6511 5 old old JJ cord-006870-f5w6fw6q 6511 6 woman woman NN cord-006870-f5w6fw6q 6511 7 with with IN cord-006870-f5w6fw6q 6511 8 hypertension hypertension NN cord-006870-f5w6fw6q 6511 9 , , , cord-006870-f5w6fw6q 6511 10 non non JJ cord-006870-f5w6fw6q 6511 11 - - JJ cord-006870-f5w6fw6q 6511 12 compliant compliant JJ cord-006870-f5w6fw6q 6511 13 on on IN cord-006870-f5w6fw6q 6511 14 medication medication NN cord-006870-f5w6fw6q 6511 15 , , , cord-006870-f5w6fw6q 6511 16 had have VBD cord-006870-f5w6fw6q 6511 17 fatigue fatigue NN cord-006870-f5w6fw6q 6511 18 and and CC cord-006870-f5w6fw6q 6511 19 2 2 CD cord-006870-f5w6fw6q 6511 20 weeks week NNS cord-006870-f5w6fw6q 6511 21 of of IN cord-006870-f5w6fw6q 6511 22 intermittent intermittent JJ cord-006870-f5w6fw6q 6511 23 left left JJ cord-006870-f5w6fw6q 6511 24 sided sided JJ cord-006870-f5w6fw6q 6511 25 weakness weakness NN cord-006870-f5w6fw6q 6511 26 when when WRB cord-006870-f5w6fw6q 6511 27 she -PRON- PRP cord-006870-f5w6fw6q 6511 28 presented present VBD cord-006870-f5w6fw6q 6511 29 to to IN cord-006870-f5w6fw6q 6511 30 an an DT cord-006870-f5w6fw6q 6511 31 outside outside JJ cord-006870-f5w6fw6q 6511 32 hospital hospital NN cord-006870-f5w6fw6q 6511 33 for for IN cord-006870-f5w6fw6q 6511 34 evaluation evaluation NN cord-006870-f5w6fw6q 6511 35 . . . cord-006870-f5w6fw6q 6512 1 Initially initially RB cord-006870-f5w6fw6q 6512 2 upon upon IN cord-006870-f5w6fw6q 6512 3 arrival arrival NN cord-006870-f5w6fw6q 6512 4 her -PRON- PRP$ cord-006870-f5w6fw6q 6512 5 Glascow Glascow NNP cord-006870-f5w6fw6q 6512 6 Coma Coma NNP cord-006870-f5w6fw6q 6512 7 Scale Scale NNP cord-006870-f5w6fw6q 6512 8 ( ( -LRB- cord-006870-f5w6fw6q 6512 9 GCS GCS NNP cord-006870-f5w6fw6q 6512 10 ) ) -RRB- cord-006870-f5w6fw6q 6512 11 was be VBD cord-006870-f5w6fw6q 6512 12 14 14 CD cord-006870-f5w6fw6q 6512 13 . . . cord-006870-f5w6fw6q 6513 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6513 2 mental mental JJ cord-006870-f5w6fw6q 6513 3 status status NN cord-006870-f5w6fw6q 6513 4 deteriorated deteriorate VBD cord-006870-f5w6fw6q 6513 5 over over IN cord-006870-f5w6fw6q 6513 6 6 6 CD cord-006870-f5w6fw6q 6513 7 hours hour NNS cord-006870-f5w6fw6q 6513 8 , , , cord-006870-f5w6fw6q 6513 9 eventually eventually RB cord-006870-f5w6fw6q 6513 10 requiring require VBG cord-006870-f5w6fw6q 6513 11 intubation intubation NN cord-006870-f5w6fw6q 6513 12 . . . cord-006870-f5w6fw6q 6514 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6514 2 peak peak NN cord-006870-f5w6fw6q 6514 3 blood blood NN cord-006870-f5w6fw6q 6514 4 pressure pressure NN cord-006870-f5w6fw6q 6514 5 was be VBD cord-006870-f5w6fw6q 6514 6 269/147 269/147 CD cord-006870-f5w6fw6q 6514 7 . . . cord-006870-f5w6fw6q 6515 1 Outside outside IN cord-006870-f5w6fw6q 6515 2 CT CT NNP cord-006870-f5w6fw6q 6515 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6515 4 scattered scatter VBN cord-006870-f5w6fw6q 6515 5 intracerebral intracerebral JJ cord-006870-f5w6fw6q 6515 6 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6515 7 ( ( -LRB- cord-006870-f5w6fw6q 6515 8 ICH ICH NNP cord-006870-f5w6fw6q 6515 9 ) ) -RRB- cord-006870-f5w6fw6q 6515 10 and and CC cord-006870-f5w6fw6q 6515 11 she -PRON- PRP cord-006870-f5w6fw6q 6515 12 was be VBD cord-006870-f5w6fw6q 6515 13 transferred transfer VBN cord-006870-f5w6fw6q 6515 14 for for IN cord-006870-f5w6fw6q 6515 15 higher high JJR cord-006870-f5w6fw6q 6515 16 level level NN cord-006870-f5w6fw6q 6515 17 of of IN cord-006870-f5w6fw6q 6515 18 care care NN cord-006870-f5w6fw6q 6515 19 . . . cord-006870-f5w6fw6q 6516 1 On on IN cord-006870-f5w6fw6q 6516 2 admission admission NN cord-006870-f5w6fw6q 6516 3 her -PRON- PRP$ cord-006870-f5w6fw6q 6516 4 GCS GCS NNP cord-006870-f5w6fw6q 6516 5 was be VBD cord-006870-f5w6fw6q 6516 6 4 4 CD cord-006870-f5w6fw6q 6516 7 . . . cord-006870-f5w6fw6q 6517 1 Review Review NNP cord-006870-f5w6fw6q 6517 2 of of IN cord-006870-f5w6fw6q 6517 3 her -PRON- PRP$ cord-006870-f5w6fw6q 6517 4 outside outside JJ cord-006870-f5w6fw6q 6517 5 CT CT NNP cord-006870-f5w6fw6q 6517 6 was be VBD cord-006870-f5w6fw6q 6517 7 remarkable remarkable JJ cord-006870-f5w6fw6q 6517 8 for for IN cord-006870-f5w6fw6q 6517 9 extreme extreme JJ cord-006870-f5w6fw6q 6517 10 right right RB cord-006870-f5w6fw6q 6517 11 - - HYPH cord-006870-f5w6fw6q 6517 12 sided sided JJ cord-006870-f5w6fw6q 6517 13 white white JJ cord-006870-f5w6fw6q 6517 14 matter matter NN cord-006870-f5w6fw6q 6517 15 hypodensity hypodensity NN cord-006870-f5w6fw6q 6517 16 , , , cord-006870-f5w6fw6q 6517 17 moderate moderate JJ cord-006870-f5w6fw6q 6517 18 left left JJ cord-006870-f5w6fw6q 6517 19 white white JJ cord-006870-f5w6fw6q 6517 20 matter matter NN cord-006870-f5w6fw6q 6517 21 hypodensity hypodensity NN cord-006870-f5w6fw6q 6517 22 , , , cord-006870-f5w6fw6q 6517 23 and and CC cord-006870-f5w6fw6q 6517 24 small small JJ cord-006870-f5w6fw6q 6517 25 scattered scatter VBN cord-006870-f5w6fw6q 6517 26 ICH ICH NNP cord-006870-f5w6fw6q 6517 27 . . . cord-006870-f5w6fw6q 6518 1 Workup workup JJ cord-006870-f5w6fw6q 6518 2 including include VBG cord-006870-f5w6fw6q 6518 3 infectious infectious JJ cord-006870-f5w6fw6q 6518 4 , , , cord-006870-f5w6fw6q 6518 5 inflammatory inflammatory JJ cord-006870-f5w6fw6q 6518 6 , , , cord-006870-f5w6fw6q 6518 7 and and CC cord-006870-f5w6fw6q 6518 8 neoplastic neoplastic JJ cord-006870-f5w6fw6q 6518 9 processes process NNS cord-006870-f5w6fw6q 6518 10 were be VBD cord-006870-f5w6fw6q 6518 11 excluded exclude VBN cord-006870-f5w6fw6q 6518 12 through through IN cord-006870-f5w6fw6q 6518 13 serum serum NN cord-006870-f5w6fw6q 6518 14 , , , cord-006870-f5w6fw6q 6518 15 CSF CSF NNP cord-006870-f5w6fw6q 6518 16 studies study NNS cord-006870-f5w6fw6q 6518 17 , , , cord-006870-f5w6fw6q 6518 18 and and CC cord-006870-f5w6fw6q 6518 19 MRI MRI NNP cord-006870-f5w6fw6q 6518 20 . . . cord-006870-f5w6fw6q 6519 1 Conventional conventional JJ cord-006870-f5w6fw6q 6519 2 angiogram angiogram NN cord-006870-f5w6fw6q 6519 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6519 4 a a DT cord-006870-f5w6fw6q 6519 5 right right JJ cord-006870-f5w6fw6q 6519 6 transverse transverse JJ cord-006870-f5w6fw6q 6519 7 sinus sinus NN cord-006870-f5w6fw6q 6519 8 dAVF davf NN cord-006870-f5w6fw6q 6519 9 with with IN cord-006870-f5w6fw6q 6519 10 reflux reflux NN cord-006870-f5w6fw6q 6519 11 into into IN cord-006870-f5w6fw6q 6519 12 cortical cortical JJ cord-006870-f5w6fw6q 6519 13 veins vein NNS cord-006870-f5w6fw6q 6519 14 , , , cord-006870-f5w6fw6q 6519 15 which which WDT cord-006870-f5w6fw6q 6519 16 was be VBD cord-006870-f5w6fw6q 6519 17 subsequently subsequently RB cord-006870-f5w6fw6q 6519 18 embolized embolize VBN cord-006870-f5w6fw6q 6519 19 . . . cord-006870-f5w6fw6q 6520 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6520 2 white white JJ cord-006870-f5w6fw6q 6520 3 matter matter NN cord-006870-f5w6fw6q 6521 1 T2-weighted t2-weighte VBN cord-006870-f5w6fw6q 6521 2 hyperintensities hyperintensitie NNS cord-006870-f5w6fw6q 6521 3 improved improve VBD cord-006870-f5w6fw6q 6521 4 on on IN cord-006870-f5w6fw6q 6521 5 follow follow NN cord-006870-f5w6fw6q 6521 6 - - HYPH cord-006870-f5w6fw6q 6521 7 up up NN cord-006870-f5w6fw6q 6521 8 MRI MRI NNP cord-006870-f5w6fw6q 6521 9 , , , cord-006870-f5w6fw6q 6521 10 and and CC cord-006870-f5w6fw6q 6521 11 her -PRON- PRP$ cord-006870-f5w6fw6q 6521 12 GCS GCS NNP cord-006870-f5w6fw6q 6521 13 was be VBD cord-006870-f5w6fw6q 6521 14 11 11 CD cord-006870-f5w6fw6q 6521 15 at at IN cord-006870-f5w6fw6q 6521 16 the the DT cord-006870-f5w6fw6q 6521 17 time time NN cord-006870-f5w6fw6q 6521 18 of of IN cord-006870-f5w6fw6q 6521 19 discharge discharge NN cord-006870-f5w6fw6q 6521 20 . . . cord-006870-f5w6fw6q 6522 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6522 2 case case NN cord-006870-f5w6fw6q 6522 3 highlights highlight VBZ cord-006870-f5w6fw6q 6522 4 the the DT cord-006870-f5w6fw6q 6522 5 possibility possibility NN cord-006870-f5w6fw6q 6522 6 of of IN cord-006870-f5w6fw6q 6522 7 asymmetric asymmetric JJ cord-006870-f5w6fw6q 6522 8 PRES PRES NNP cord-006870-f5w6fw6q 6522 9 due due IN cord-006870-f5w6fw6q 6522 10 to to IN cord-006870-f5w6fw6q 6522 11 abnormal abnormal JJ cord-006870-f5w6fw6q 6522 12 venous venous JJ cord-006870-f5w6fw6q 6522 13 congestion congestion NN cord-006870-f5w6fw6q 6522 14 due due IN cord-006870-f5w6fw6q 6522 15 to to IN cord-006870-f5w6fw6q 6522 16 the the DT cord-006870-f5w6fw6q 6522 17 right right RB cord-006870-f5w6fw6q 6522 18 - - HYPH cord-006870-f5w6fw6q 6522 19 sided sided JJ cord-006870-f5w6fw6q 6522 20 dAVF davf NN cord-006870-f5w6fw6q 6522 21 . . . cord-006870-f5w6fw6q 6523 1 Venous venous JJ cord-006870-f5w6fw6q 6523 2 hypertension hypertension NN cord-006870-f5w6fw6q 6523 3 likely likely RB cord-006870-f5w6fw6q 6523 4 caused cause VBD cord-006870-f5w6fw6q 6523 5 the the DT cord-006870-f5w6fw6q 6523 6 patient patient NN cord-006870-f5w6fw6q 6523 7 's 's POS cord-006870-f5w6fw6q 6523 8 intermittent intermittent JJ cord-006870-f5w6fw6q 6523 9 left left JJ cord-006870-f5w6fw6q 6523 10 sided sided JJ cord-006870-f5w6fw6q 6523 11 symptoms symptom NNS cord-006870-f5w6fw6q 6523 12 in in IN cord-006870-f5w6fw6q 6523 13 the the DT cord-006870-f5w6fw6q 6523 14 weeks week NNS cord-006870-f5w6fw6q 6523 15 prior prior RB cord-006870-f5w6fw6q 6523 16 to to IN cord-006870-f5w6fw6q 6523 17 admission admission NN cord-006870-f5w6fw6q 6523 18 . . . cord-006870-f5w6fw6q 6524 1 Few few JJ cord-006870-f5w6fw6q 6524 2 cases case NNS cord-006870-f5w6fw6q 6524 3 of of IN cord-006870-f5w6fw6q 6524 4 unilateral unilateral JJ cord-006870-f5w6fw6q 6524 5 or or CC cord-006870-f5w6fw6q 6524 6 asymmetric asymmetric JJ cord-006870-f5w6fw6q 6524 7 PRES PRES NNP cord-006870-f5w6fw6q 6524 8 have have VBP cord-006870-f5w6fw6q 6524 9 been be VBN cord-006870-f5w6fw6q 6524 10 reported report VBN cord-006870-f5w6fw6q 6524 11 following follow VBG cord-006870-f5w6fw6q 6524 12 induced induce VBN cord-006870-f5w6fw6q 6524 13 hypertension hypertension NN cord-006870-f5w6fw6q 6524 14 for for IN cord-006870-f5w6fw6q 6524 15 treatment treatment NN cord-006870-f5w6fw6q 6524 16 of of IN cord-006870-f5w6fw6q 6524 17 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6524 18 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6524 19 or or CC cord-006870-f5w6fw6q 6524 20 in in IN cord-006870-f5w6fw6q 6524 21 the the DT cord-006870-f5w6fw6q 6524 22 setting setting NN cord-006870-f5w6fw6q 6524 23 of of IN cord-006870-f5w6fw6q 6524 24 vascular vascular JJ cord-006870-f5w6fw6q 6524 25 malformation malformation NN cord-006870-f5w6fw6q 6524 26 . . . cord-006870-f5w6fw6q 6525 1 To to IN cord-006870-f5w6fw6q 6525 2 our -PRON- PRP$ cord-006870-f5w6fw6q 6525 3 knowledge knowledge NN cord-006870-f5w6fw6q 6525 4 , , , cord-006870-f5w6fw6q 6525 5 this this DT cord-006870-f5w6fw6q 6525 6 is be VBZ cord-006870-f5w6fw6q 6525 7 the the DT cord-006870-f5w6fw6q 6525 8 only only JJ cord-006870-f5w6fw6q 6525 9 case case NN cord-006870-f5w6fw6q 6525 10 of of IN cord-006870-f5w6fw6q 6525 11 severely severely RB cord-006870-f5w6fw6q 6525 12 asymmetric asymmetric JJ cord-006870-f5w6fw6q 6525 13 PRES PRES NNP cord-006870-f5w6fw6q 6525 14 and and CC cord-006870-f5w6fw6q 6525 15 preceding precede VBG cord-006870-f5w6fw6q 6525 16 stroke stroke NN cord-006870-f5w6fw6q 6525 17 like like IN cord-006870-f5w6fw6q 6525 18 symptoms symptom NNS cord-006870-f5w6fw6q 6525 19 due due JJ cord-006870-f5w6fw6q 6525 20 to to IN cord-006870-f5w6fw6q 6525 21 a a DT cord-006870-f5w6fw6q 6525 22 dAVF davf NN cord-006870-f5w6fw6q 6525 23 . . . cord-006870-f5w6fw6q 6526 1 The the DT cord-006870-f5w6fw6q 6526 2 most most RBS cord-006870-f5w6fw6q 6526 3 common common JJ cord-006870-f5w6fw6q 6526 4 pathology pathology NN cord-006870-f5w6fw6q 6526 5 associated associate VBN cord-006870-f5w6fw6q 6526 6 with with IN cord-006870-f5w6fw6q 6526 7 an an DT cord-006870-f5w6fw6q 6526 8 intraluminal intraluminal JJ cord-006870-f5w6fw6q 6526 9 carotid carotid JJ cord-006870-f5w6fw6q 6526 10 thrombus thrombus NN cord-006870-f5w6fw6q 6526 11 is be VBZ cord-006870-f5w6fw6q 6526 12 underlying underlie VBG cord-006870-f5w6fw6q 6526 13 atherosclerosis atherosclerosis NN cord-006870-f5w6fw6q 6526 14 . . . cord-006870-f5w6fw6q 6527 1 In in IN cord-006870-f5w6fw6q 6527 2 rare rare JJ cord-006870-f5w6fw6q 6527 3 cases case NNS cord-006870-f5w6fw6q 6527 4 it -PRON- PRP cord-006870-f5w6fw6q 6527 5 may may MD cord-006870-f5w6fw6q 6527 6 be be VB cord-006870-f5w6fw6q 6527 7 associated associate VBN cord-006870-f5w6fw6q 6527 8 to to IN cord-006870-f5w6fw6q 6527 9 thrombocytosis thrombocytosis NNP cord-006870-f5w6fw6q 6527 10 . . . cord-006870-f5w6fw6q 6528 1 Currently currently RB cord-006870-f5w6fw6q 6528 2 there there EX cord-006870-f5w6fw6q 6528 3 are be VBP cord-006870-f5w6fw6q 6528 4 no no DT cord-006870-f5w6fw6q 6528 5 clear clear JJ cord-006870-f5w6fw6q 6528 6 recommendations recommendation NNS cord-006870-f5w6fw6q 6528 7 for for IN cord-006870-f5w6fw6q 6528 8 the the DT cord-006870-f5w6fw6q 6528 9 treatment treatment NN cord-006870-f5w6fw6q 6528 10 of of IN cord-006870-f5w6fw6q 6528 11 ischemic ischemic JJ cord-006870-f5w6fw6q 6528 12 stroke stroke NN cord-006870-f5w6fw6q 6528 13 associated associate VBN cord-006870-f5w6fw6q 6528 14 with with IN cord-006870-f5w6fw6q 6528 15 thrombocytosis thrombocytosis NNP cord-006870-f5w6fw6q 6528 16 . . . cord-006870-f5w6fw6q 6529 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6529 2 case case NN cord-006870-f5w6fw6q 6529 3 describes describe VBZ cord-006870-f5w6fw6q 6529 4 the the DT cord-006870-f5w6fw6q 6529 5 use use NN cord-006870-f5w6fw6q 6529 6 of of IN cord-006870-f5w6fw6q 6529 7 plateletpheresis plateletpheresis NN cord-006870-f5w6fw6q 6529 8 for for IN cord-006870-f5w6fw6q 6529 9 the the DT cord-006870-f5w6fw6q 6529 10 acute acute JJ cord-006870-f5w6fw6q 6529 11 management management NN cord-006870-f5w6fw6q 6529 12 of of IN cord-006870-f5w6fw6q 6529 13 thrombocytosis thrombocytosis NNP cord-006870-f5w6fw6q 6529 14 complicated complicate VBN cord-006870-f5w6fw6q 6529 15 by by IN cord-006870-f5w6fw6q 6529 16 an an DT cord-006870-f5w6fw6q 6529 17 internal internal JJ cord-006870-f5w6fw6q 6529 18 carotid carotid JJ cord-006870-f5w6fw6q 6529 19 artery artery NN cord-006870-f5w6fw6q 6529 20 thrombus thrombus NN cord-006870-f5w6fw6q 6529 21 resulting result VBG cord-006870-f5w6fw6q 6529 22 in in IN cord-006870-f5w6fw6q 6529 23 a a DT cord-006870-f5w6fw6q 6529 24 right right JJ cord-006870-f5w6fw6q 6529 25 MCA MCA NNP cord-006870-f5w6fw6q 6529 26 stroke stroke NN cord-006870-f5w6fw6q 6529 27 . . . cord-006870-f5w6fw6q 6530 1 A a DT cord-006870-f5w6fw6q 6530 2 55-year 55-year JJ cord-006870-f5w6fw6q 6530 3 - - HYPH cord-006870-f5w6fw6q 6530 4 old old JJ cord-006870-f5w6fw6q 6530 5 female female NN cord-006870-f5w6fw6q 6530 6 with with IN cord-006870-f5w6fw6q 6530 7 past past JJ cord-006870-f5w6fw6q 6530 8 medical medical JJ cord-006870-f5w6fw6q 6530 9 history history NN cord-006870-f5w6fw6q 6530 10 of of IN cord-006870-f5w6fw6q 6530 11 menorrhagia menorrhagia NN cord-006870-f5w6fw6q 6530 12 who who WP cord-006870-f5w6fw6q 6530 13 presented present VBD cord-006870-f5w6fw6q 6530 14 complaining complaining NN cord-006870-f5w6fw6q 6530 15 of of IN cord-006870-f5w6fw6q 6530 16 left left JJ cord-006870-f5w6fw6q 6530 17 face face NN cord-006870-f5w6fw6q 6530 18 , , , cord-006870-f5w6fw6q 6530 19 arm arm NN cord-006870-f5w6fw6q 6530 20 and and CC cord-006870-f5w6fw6q 6530 21 leg leg NN cord-006870-f5w6fw6q 6530 22 weakness weakness NN cord-006870-f5w6fw6q 6530 23 with with IN cord-006870-f5w6fw6q 6530 24 associated associated JJ cord-006870-f5w6fw6q 6530 25 shortness shortness NN cord-006870-f5w6fw6q 6530 26 of of IN cord-006870-f5w6fw6q 6530 27 breath breath NN cord-006870-f5w6fw6q 6530 28 . . . cord-006870-f5w6fw6q 6531 1 Upon upon IN cord-006870-f5w6fw6q 6531 2 arrival arrival NN cord-006870-f5w6fw6q 6531 3 her -PRON- PRP$ cord-006870-f5w6fw6q 6531 4 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6531 5 was be VBD cord-006870-f5w6fw6q 6531 6 1 1 CD cord-006870-f5w6fw6q 6531 7 and and CC cord-006870-f5w6fw6q 6531 8 the the DT cord-006870-f5w6fw6q 6531 9 initial initial JJ cord-006870-f5w6fw6q 6531 10 head head NN cord-006870-f5w6fw6q 6531 11 CT CT NNP cord-006870-f5w6fw6q 6531 12 was be VBD cord-006870-f5w6fw6q 6531 13 unremarkable unremarkable JJ cord-006870-f5w6fw6q 6531 14 . . . cord-006870-f5w6fw6q 6532 1 Laboratory laboratory NN cord-006870-f5w6fw6q 6532 2 results result NNS cord-006870-f5w6fw6q 6532 3 revealed reveal VBD cord-006870-f5w6fw6q 6532 4 a a DT cord-006870-f5w6fw6q 6532 5 hemoglobin hemoglobin NN cord-006870-f5w6fw6q 6532 6 8.2 8.2 CD cord-006870-f5w6fw6q 6532 7 mg mg NNP cord-006870-f5w6fw6q 6532 8 / / SYM cord-006870-f5w6fw6q 6532 9 dL dl NN cord-006870-f5w6fw6q 6532 10 , , , cord-006870-f5w6fw6q 6532 11 hematocrit hematocrit NN cord-006870-f5w6fw6q 6532 12 30 30 CD cord-006870-f5w6fw6q 6532 13 mg mg NN cord-006870-f5w6fw6q 6532 14 / / SYM cord-006870-f5w6fw6q 6532 15 dL dl NN cord-006870-f5w6fw6q 6532 16 , , , cord-006870-f5w6fw6q 6532 17 and and CC cord-006870-f5w6fw6q 6532 18 platelet platelet NN cord-006870-f5w6fw6q 6532 19 count count NN cord-006870-f5w6fw6q 6532 20 of of IN cord-006870-f5w6fw6q 6532 21 1014 1014 CD cord-006870-f5w6fw6q 6532 22 x x SYM cord-006870-f5w6fw6q 6532 23 103 103 CD cord-006870-f5w6fw6q 6533 1 /mL. /mL. NFP cord-006870-f5w6fw6q 6533 2 She -PRON- PRP cord-006870-f5w6fw6q 6533 3 was be VBD cord-006870-f5w6fw6q 6533 4 not not RB cord-006870-f5w6fw6q 6533 5 a a DT cord-006870-f5w6fw6q 6533 6 candidate candidate NN cord-006870-f5w6fw6q 6533 7 for for IN cord-006870-f5w6fw6q 6533 8 thrombolytic thrombolytic NN cord-006870-f5w6fw6q 6533 9 therapy therapy NN cord-006870-f5w6fw6q 6533 10 due due IN cord-006870-f5w6fw6q 6533 11 to to IN cord-006870-f5w6fw6q 6533 12 the the DT cord-006870-f5w6fw6q 6533 13 time time NN cord-006870-f5w6fw6q 6533 14 window window NN cord-006870-f5w6fw6q 6533 15 . . . cord-006870-f5w6fw6q 6534 1 Soon soon RB cord-006870-f5w6fw6q 6534 2 after after IN cord-006870-f5w6fw6q 6534 3 admission admission NN cord-006870-f5w6fw6q 6534 4 she -PRON- PRP cord-006870-f5w6fw6q 6534 5 had have VBD cord-006870-f5w6fw6q 6534 6 acute acute JJ cord-006870-f5w6fw6q 6534 7 worsening worsen VBG cord-006870-f5w6fw6q 6534 8 of of IN cord-006870-f5w6fw6q 6534 9 symptoms symptom NNS cord-006870-f5w6fw6q 6534 10 with with IN cord-006870-f5w6fw6q 6534 11 an an DT cord-006870-f5w6fw6q 6534 12 NIHSS NIHSS NNP cord-006870-f5w6fw6q 6534 13 of of IN cord-006870-f5w6fw6q 6534 14 17 17 CD cord-006870-f5w6fw6q 6534 15 . . . cord-006870-f5w6fw6q 6535 1 A a DT cord-006870-f5w6fw6q 6535 2 CTA cta NN cord-006870-f5w6fw6q 6535 3 of of IN cord-006870-f5w6fw6q 6535 4 the the DT cord-006870-f5w6fw6q 6535 5 head head NN cord-006870-f5w6fw6q 6535 6 and and CC cord-006870-f5w6fw6q 6535 7 neck neck NN cord-006870-f5w6fw6q 6535 8 showed show VBD cord-006870-f5w6fw6q 6535 9 acute acute JJ cord-006870-f5w6fw6q 6535 10 ischemic ischemic JJ cord-006870-f5w6fw6q 6535 11 infarction infarction NN cord-006870-f5w6fw6q 6535 12 involving involve VBG cord-006870-f5w6fw6q 6535 13 the the DT cord-006870-f5w6fw6q 6535 14 right right JJ cord-006870-f5w6fw6q 6535 15 MCA MCA NNP cord-006870-f5w6fw6q 6535 16 territory territory NN cord-006870-f5w6fw6q 6535 17 with with IN cord-006870-f5w6fw6q 6535 18 non non JJ cord-006870-f5w6fw6q 6535 19 - - JJ cord-006870-f5w6fw6q 6535 20 occlusive occlusive JJ cord-006870-f5w6fw6q 6535 21 intraluminal intraluminal JJ cord-006870-f5w6fw6q 6535 22 thrombus thrombus NN cord-006870-f5w6fw6q 6535 23 within within IN cord-006870-f5w6fw6q 6535 24 the the DT cord-006870-f5w6fw6q 6535 25 right right JJ cord-006870-f5w6fw6q 6535 26 carotid carotid JJ cord-006870-f5w6fw6q 6535 27 bulb bulb NN cord-006870-f5w6fw6q 6535 28 . . . cord-006870-f5w6fw6q 6536 1 ASA ASA NNP cord-006870-f5w6fw6q 6536 2 325 325 CD cord-006870-f5w6fw6q 6536 3 mg mg NNP cord-006870-f5w6fw6q 6536 4 and and CC cord-006870-f5w6fw6q 6536 5 heparin heparin JJ cord-006870-f5w6fw6q 6536 6 infusion infusion NN cord-006870-f5w6fw6q 6536 7 were be VBD cord-006870-f5w6fw6q 6536 8 initiated initiate VBN cord-006870-f5w6fw6q 6536 9 promptly promptly RB cord-006870-f5w6fw6q 6536 10 . . . cord-006870-f5w6fw6q 6537 1 After after IN cord-006870-f5w6fw6q 6537 2 a a DT cord-006870-f5w6fw6q 6537 3 thorough thorough JJ cord-006870-f5w6fw6q 6537 4 work work NN cord-006870-f5w6fw6q 6537 5 - - HYPH cord-006870-f5w6fw6q 6537 6 up up NN cord-006870-f5w6fw6q 6537 7 for for IN cord-006870-f5w6fw6q 6537 8 thrombocytosis thrombocytosis NNP cord-006870-f5w6fw6q 6537 9 , , , cord-006870-f5w6fw6q 6537 10 reactive reactive JJ cord-006870-f5w6fw6q 6537 11 thrombocytosis thrombocytosis NN cord-006870-f5w6fw6q 6537 12 secondary secondary JJ cord-006870-f5w6fw6q 6537 13 to to IN cord-006870-f5w6fw6q 6537 14 iron iron NN cord-006870-f5w6fw6q 6537 15 deficiency deficiency NN cord-006870-f5w6fw6q 6537 16 anemia anemia NN cord-006870-f5w6fw6q 6537 17 was be VBD cord-006870-f5w6fw6q 6537 18 diagnosed diagnose VBN cord-006870-f5w6fw6q 6537 19 . . . cord-006870-f5w6fw6q 6538 1 Plateletpheresis Plateletpheresis NNP cord-006870-f5w6fw6q 6538 2 as as RB cord-006870-f5w6fw6q 6538 3 well well RB cord-006870-f5w6fw6q 6538 4 as as IN cord-006870-f5w6fw6q 6538 5 oral oral JJ cord-006870-f5w6fw6q 6538 6 ferrous ferrous JJ cord-006870-f5w6fw6q 6538 7 sulfate sulfate NN cord-006870-f5w6fw6q 6538 8 were be VBD cord-006870-f5w6fw6q 6538 9 started start VBN cord-006870-f5w6fw6q 6538 10 . . . cord-006870-f5w6fw6q 6539 1 After after IN cord-006870-f5w6fw6q 6539 2 one one CD cord-006870-f5w6fw6q 6539 3 plateletpheresis plateletpheresis NN cord-006870-f5w6fw6q 6539 4 cycle cycle NN cord-006870-f5w6fw6q 6539 5 the the DT cord-006870-f5w6fw6q 6539 6 platelet platelet NN cord-006870-f5w6fw6q 6539 7 count count NN cord-006870-f5w6fw6q 6539 8 stabilized stabilize VBD cord-006870-f5w6fw6q 6539 9 at at IN cord-006870-f5w6fw6q 6539 10 400x103/ 400x103/ CD cord-006870-f5w6fw6q 6540 1 mL. mL. NFP cord-006870-f5w6fw6q 6540 2 Complete complete JJ cord-006870-f5w6fw6q 6540 3 thrombus thrombus NN cord-006870-f5w6fw6q 6540 4 resolution resolution NN cord-006870-f5w6fw6q 6540 5 was be VBD cord-006870-f5w6fw6q 6540 6 confirmed confirm VBN cord-006870-f5w6fw6q 6540 7 on on IN cord-006870-f5w6fw6q 6540 8 follow follow NN cord-006870-f5w6fw6q 6540 9 - - HYPH cord-006870-f5w6fw6q 6540 10 up up NN cord-006870-f5w6fw6q 6540 11 CTA CTA NNP cord-006870-f5w6fw6q 6540 12 on on IN cord-006870-f5w6fw6q 6540 13 day day NN cord-006870-f5w6fw6q 6540 14 10 10 CD cord-006870-f5w6fw6q 6540 15 of of IN cord-006870-f5w6fw6q 6540 16 admission admission NN cord-006870-f5w6fw6q 6540 17 without without IN cord-006870-f5w6fw6q 6540 18 need need NN cord-006870-f5w6fw6q 6540 19 for for IN cord-006870-f5w6fw6q 6540 20 surgical surgical JJ cord-006870-f5w6fw6q 6540 21 revascularization revascularization NN cord-006870-f5w6fw6q 6540 22 . . . cord-006870-f5w6fw6q 6541 1 The the DT cord-006870-f5w6fw6q 6541 2 role role NN cord-006870-f5w6fw6q 6541 3 for for IN cord-006870-f5w6fw6q 6541 4 plateletpheresis plateletpheresis NN cord-006870-f5w6fw6q 6541 5 is be VBZ cord-006870-f5w6fw6q 6541 6 not not RB cord-006870-f5w6fw6q 6541 7 well well RB cord-006870-f5w6fw6q 6541 8 established establish VBN cord-006870-f5w6fw6q 6541 9 in in IN cord-006870-f5w6fw6q 6541 10 secondary secondary JJ cord-006870-f5w6fw6q 6541 11 thrombocytosis thrombocytosis NN cord-006870-f5w6fw6q 6541 12 . . . cord-006870-f5w6fw6q 6542 1 In in IN cord-006870-f5w6fw6q 6542 2 cases case NNS cord-006870-f5w6fw6q 6542 3 with with IN cord-006870-f5w6fw6q 6542 4 extreme extreme JJ cord-006870-f5w6fw6q 6542 5 thrombocytosis thrombocytosis NN cord-006870-f5w6fw6q 6542 6 immediate immediate JJ cord-006870-f5w6fw6q 6542 7 surgical surgical JJ cord-006870-f5w6fw6q 6542 8 thrombectomy thrombectomy NN cord-006870-f5w6fw6q 6542 9 may may MD cord-006870-f5w6fw6q 6542 10 be be VB cord-006870-f5w6fw6q 6542 11 contraindicated contraindicate VBN cord-006870-f5w6fw6q 6542 12 due due IN cord-006870-f5w6fw6q 6542 13 to to IN cord-006870-f5w6fw6q 6542 14 high high JJ cord-006870-f5w6fw6q 6542 15 risk risk NN cord-006870-f5w6fw6q 6542 16 of of IN cord-006870-f5w6fw6q 6542 17 rethrombosis rethrombosis NN cord-006870-f5w6fw6q 6542 18 . . . cord-006870-f5w6fw6q 6543 1 Urgent urgent JJ cord-006870-f5w6fw6q 6543 2 cytoreduction cytoreduction NN cord-006870-f5w6fw6q 6543 3 with with IN cord-006870-f5w6fw6q 6543 4 correction correction NN cord-006870-f5w6fw6q 6543 5 of of IN cord-006870-f5w6fw6q 6543 6 the the DT cord-006870-f5w6fw6q 6543 7 putative putative JJ cord-006870-f5w6fw6q 6543 8 mechanism mechanism NN cord-006870-f5w6fw6q 6543 9 for for IN cord-006870-f5w6fw6q 6543 10 thromboyctosis thromboyctosis NNP cord-006870-f5w6fw6q 6543 11 should should MD cord-006870-f5w6fw6q 6543 12 be be VB cord-006870-f5w6fw6q 6543 13 undertaken undertake VBN cord-006870-f5w6fw6q 6543 14 for for IN cord-006870-f5w6fw6q 6543 15 optimal optimal JJ cord-006870-f5w6fw6q 6543 16 management management NN cord-006870-f5w6fw6q 6543 17 . . . cord-006870-f5w6fw6q 6544 1 Plateletpheresis Plateletpheresis NNP cord-006870-f5w6fw6q 6544 2 is be VBZ cord-006870-f5w6fw6q 6544 3 safe safe JJ cord-006870-f5w6fw6q 6544 4 and and CC cord-006870-f5w6fw6q 6544 5 efficient efficient JJ cord-006870-f5w6fw6q 6544 6 in in IN cord-006870-f5w6fw6q 6544 7 reducing reduce VBG cord-006870-f5w6fw6q 6544 8 the the DT cord-006870-f5w6fw6q 6544 9 platelet platelet NN cord-006870-f5w6fw6q 6544 10 count count NN cord-006870-f5w6fw6q 6544 11 to to TO cord-006870-f5w6fw6q 6544 12 decrease decrease VB cord-006870-f5w6fw6q 6544 13 the the DT cord-006870-f5w6fw6q 6544 14 risk risk NN cord-006870-f5w6fw6q 6544 15 of of IN cord-006870-f5w6fw6q 6544 16 clot clot NN cord-006870-f5w6fw6q 6544 17 progression progression NN cord-006870-f5w6fw6q 6544 18 or or CC cord-006870-f5w6fw6q 6544 19 further further JJ cord-006870-f5w6fw6q 6544 20 clot clot NN cord-006870-f5w6fw6q 6544 21 formations formation NNS cord-006870-f5w6fw6q 6544 22 which which WDT cord-006870-f5w6fw6q 6544 23 could could MD cord-006870-f5w6fw6q 6544 24 worsen worsen VB cord-006870-f5w6fw6q 6544 25 patient patient JJ cord-006870-f5w6fw6q 6544 26 outcome outcome NN cord-006870-f5w6fw6q 6544 27 . . . cord-006870-f5w6fw6q 6545 1 Hyperpyrexia Hyperpyrexia NNP cord-006870-f5w6fw6q 6545 2 is be VBZ cord-006870-f5w6fw6q 6545 3 an an DT cord-006870-f5w6fw6q 6545 4 elevated elevated JJ cord-006870-f5w6fw6q 6545 5 core core NN cord-006870-f5w6fw6q 6545 6 body body NN cord-006870-f5w6fw6q 6545 7 temperature temperature NN cord-006870-f5w6fw6q 6545 8 secondary secondary JJ cord-006870-f5w6fw6q 6545 9 to to IN cord-006870-f5w6fw6q 6545 10 an an DT cord-006870-f5w6fw6q 6545 11 elevated elevated JJ cord-006870-f5w6fw6q 6545 12 hypothalamic hypothalamic JJ cord-006870-f5w6fw6q 6545 13 set set NN cord-006870-f5w6fw6q 6545 14 temperature temperature NN cord-006870-f5w6fw6q 6545 15 . . . cord-006870-f5w6fw6q 6546 1 Hyperthermia hyperthermia NN cord-006870-f5w6fw6q 6546 2 is be VBZ cord-006870-f5w6fw6q 6546 3 an an DT cord-006870-f5w6fw6q 6546 4 elevated elevated JJ cord-006870-f5w6fw6q 6546 5 core core NN cord-006870-f5w6fw6q 6546 6 body body NN cord-006870-f5w6fw6q 6546 7 temperature temperature NN cord-006870-f5w6fw6q 6546 8 beyond beyond IN cord-006870-f5w6fw6q 6546 9 the the DT cord-006870-f5w6fw6q 6546 10 normal normal JJ cord-006870-f5w6fw6q 6546 11 hypothalamic hypothalamic JJ cord-006870-f5w6fw6q 6546 12 set set NN cord-006870-f5w6fw6q 6546 13 temperature temperature NN cord-006870-f5w6fw6q 6546 14 . . . cord-006870-f5w6fw6q 6547 1 Intracranial intracranial JJ cord-006870-f5w6fw6q 6547 2 hypotension hypotension NN cord-006870-f5w6fw6q 6547 3 can can MD cord-006870-f5w6fw6q 6547 4 present present VB cord-006870-f5w6fw6q 6547 5 with with IN cord-006870-f5w6fw6q 6547 6 a a DT cord-006870-f5w6fw6q 6547 7 wide wide JJ cord-006870-f5w6fw6q 6547 8 variety variety NN cord-006870-f5w6fw6q 6547 9 of of IN cord-006870-f5w6fw6q 6547 10 symptoms symptom NNS cord-006870-f5w6fw6q 6547 11 ranging range VBG cord-006870-f5w6fw6q 6547 12 from from IN cord-006870-f5w6fw6q 6547 13 orthostatic orthostatic JJ cord-006870-f5w6fw6q 6547 14 headache headache NN cord-006870-f5w6fw6q 6547 15 up up IN cord-006870-f5w6fw6q 6547 16 to to IN cord-006870-f5w6fw6q 6547 17 coma coma NN cord-006870-f5w6fw6q 6547 18 . . . cord-006870-f5w6fw6q 6548 1 It -PRON- PRP cord-006870-f5w6fw6q 6548 2 has have VBZ cord-006870-f5w6fw6q 6548 3 never never RB cord-006870-f5w6fw6q 6548 4 been be VBN cord-006870-f5w6fw6q 6548 5 reported report VBN cord-006870-f5w6fw6q 6548 6 to to TO cord-006870-f5w6fw6q 6548 7 present present VB cord-006870-f5w6fw6q 6548 8 with with IN cord-006870-f5w6fw6q 6548 9 fever fever NN cord-006870-f5w6fw6q 6548 10 , , , cord-006870-f5w6fw6q 6548 11 namely namely RB cord-006870-f5w6fw6q 6548 12 hyperpyrexia hyperpyrexia NNP cord-006870-f5w6fw6q 6548 13 . . . cord-006870-f5w6fw6q 6549 1 A a DT cord-006870-f5w6fw6q 6549 2 case case NN cord-006870-f5w6fw6q 6549 3 report report NN cord-006870-f5w6fw6q 6549 4 of of IN cord-006870-f5w6fw6q 6549 5 a a DT cord-006870-f5w6fw6q 6549 6 55 55 CD cord-006870-f5w6fw6q 6549 7 year year NN cord-006870-f5w6fw6q 6549 8 old old JJ cord-006870-f5w6fw6q 6549 9 female female JJ cord-006870-f5w6fw6q 6549 10 patient patient NN cord-006870-f5w6fw6q 6549 11 with with IN cord-006870-f5w6fw6q 6549 12 a a DT cord-006870-f5w6fw6q 6549 13 history history NN cord-006870-f5w6fw6q 6549 14 of of IN cord-006870-f5w6fw6q 6549 15 depression depression NN cord-006870-f5w6fw6q 6549 16 , , , cord-006870-f5w6fw6q 6549 17 diabetes diabete VBZ cord-006870-f5w6fw6q 6549 18 mellitus mellitus NN cord-006870-f5w6fw6q 6549 19 , , , cord-006870-f5w6fw6q 6549 20 hypertension hypertension NN cord-006870-f5w6fw6q 6549 21 , , , cord-006870-f5w6fw6q 6549 22 and and CC cord-006870-f5w6fw6q 6549 23 angiogram angiogram VB cord-006870-f5w6fw6q 6549 24 negative negative JJ cord-006870-f5w6fw6q 6549 25 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6549 26 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6549 27 status status NN cord-006870-f5w6fw6q 6549 28 post post NN cord-006870-f5w6fw6q 6549 29 ventriculo ventriculo JJ cord-006870-f5w6fw6q 6549 30 - - HYPH cord-006870-f5w6fw6q 6549 31 peritoneal peritoneal JJ cord-006870-f5w6fw6q 6549 32 ( ( -LRB- cord-006870-f5w6fw6q 6549 33 VP VP NNP cord-006870-f5w6fw6q 6549 34 ) ) -RRB- cord-006870-f5w6fw6q 6549 35 shunt shunt NN cord-006870-f5w6fw6q 6549 36 placement placement NN cord-006870-f5w6fw6q 6550 1 six six CD cord-006870-f5w6fw6q 6550 2 years year NNS cord-006870-f5w6fw6q 6550 3 ago ago RB cord-006870-f5w6fw6q 6550 4 who who WP cord-006870-f5w6fw6q 6550 5 was be VBD cord-006870-f5w6fw6q 6550 6 complaining complain VBG cord-006870-f5w6fw6q 6550 7 of of IN cord-006870-f5w6fw6q 6550 8 worsening worsen VBG cord-006870-f5w6fw6q 6550 9 headaches headache NNS cord-006870-f5w6fw6q 6550 10 and and CC cord-006870-f5w6fw6q 6550 11 slurred slur VBD cord-006870-f5w6fw6q 6550 12 speech speech NN cord-006870-f5w6fw6q 6550 13 for for IN cord-006870-f5w6fw6q 6550 14 the the DT cord-006870-f5w6fw6q 6550 15 past past JJ cord-006870-f5w6fw6q 6550 16 three three CD cord-006870-f5w6fw6q 6550 17 months month NNS cord-006870-f5w6fw6q 6550 18 but but CC cord-006870-f5w6fw6q 6550 19 acutely acutely RB cord-006870-f5w6fw6q 6550 20 decompensated decompensate VBD cord-006870-f5w6fw6q 6550 21 one one CD cord-006870-f5w6fw6q 6550 22 morning morning NN cord-006870-f5w6fw6q 6550 23 . . . cord-006870-f5w6fw6q 6551 1 She -PRON- PRP cord-006870-f5w6fw6q 6551 2 suddenly suddenly RB cord-006870-f5w6fw6q 6551 3 became become VBD cord-006870-f5w6fw6q 6551 4 confused confused JJ cord-006870-f5w6fw6q 6551 5 and and CC cord-006870-f5w6fw6q 6551 6 agitated agitated JJ cord-006870-f5w6fw6q 6551 7 but but CC cord-006870-f5w6fw6q 6551 8 became become VBD cord-006870-f5w6fw6q 6551 9 obtunded obtunded JJ cord-006870-f5w6fw6q 6551 10 . . . cord-006870-f5w6fw6q 6552 1 Initially initially RB cord-006870-f5w6fw6q 6552 2 , , , cord-006870-f5w6fw6q 6552 3 she -PRON- PRP cord-006870-f5w6fw6q 6552 4 was be VBD cord-006870-f5w6fw6q 6552 5 given give VBN cord-006870-f5w6fw6q 6552 6 Haldol Haldol NNP cord-006870-f5w6fw6q 6552 7 . . . cord-006870-f5w6fw6q 6553 1 She -PRON- PRP cord-006870-f5w6fw6q 6553 2 was be VBD cord-006870-f5w6fw6q 6553 3 found find VBN cord-006870-f5w6fw6q 6553 4 to to TO cord-006870-f5w6fw6q 6553 5 be be VB cord-006870-f5w6fw6q 6553 6 febrile febrile JJ cord-006870-f5w6fw6q 6553 7 ( ( -LRB- cord-006870-f5w6fw6q 6553 8 rectal rectal JJ cord-006870-f5w6fw6q 6553 9 temperature temperature NN cord-006870-f5w6fw6q 6553 10 of of IN cord-006870-f5w6fw6q 6553 11 104.8 104.8 CD cord-006870-f5w6fw6q 6553 12 F F NNP cord-006870-f5w6fw6q 6553 13 ) ) -RRB- cord-006870-f5w6fw6q 6553 14 . . . cord-006870-f5w6fw6q 6554 1 She -PRON- PRP cord-006870-f5w6fw6q 6554 2 was be VBD cord-006870-f5w6fw6q 6554 3 given give VBN cord-006870-f5w6fw6q 6554 4 dantrolene dantrolene NN cord-006870-f5w6fw6q 6554 5 and and CC cord-006870-f5w6fw6q 6554 6 bromocriptine bromocriptine NN cord-006870-f5w6fw6q 6554 7 for for IN cord-006870-f5w6fw6q 6554 8 suspected suspect VBN cord-006870-f5w6fw6q 6554 9 malignant malignant JJ cord-006870-f5w6fw6q 6554 10 neuroleptic neuroleptic JJ cord-006870-f5w6fw6q 6554 11 syndrome syndrome NN cord-006870-f5w6fw6q 6554 12 with with IN cord-006870-f5w6fw6q 6554 13 no no DT cord-006870-f5w6fw6q 6554 14 effect effect NN cord-006870-f5w6fw6q 6554 15 . . . cord-006870-f5w6fw6q 6555 1 Creatine creatine NN cord-006870-f5w6fw6q 6555 2 phospho phospho NN cord-006870-f5w6fw6q 6555 3 - - HYPH cord-006870-f5w6fw6q 6555 4 kinase kinase NN cord-006870-f5w6fw6q 6555 5 was be VBD cord-006870-f5w6fw6q 6555 6 not not RB cord-006870-f5w6fw6q 6555 7 elevated elevated JJ cord-006870-f5w6fw6q 6555 8 . . . cord-006870-f5w6fw6q 6556 1 She -PRON- PRP cord-006870-f5w6fw6q 6556 2 underwent undergo VBD cord-006870-f5w6fw6q 6556 3 infectious infectious JJ cord-006870-f5w6fw6q 6556 4 work work NN cord-006870-f5w6fw6q 6556 5 up up RB cord-006870-f5w6fw6q 6556 6 which which WDT cord-006870-f5w6fw6q 6556 7 later later RB cord-006870-f5w6fw6q 6556 8 came come VBD cord-006870-f5w6fw6q 6556 9 negative negative JJ cord-006870-f5w6fw6q 6556 10 . . . cord-006870-f5w6fw6q 6557 1 Cooling cool VBG cord-006870-f5w6fw6q 6557 2 measures measure NNS cord-006870-f5w6fw6q 6557 3 like like IN cord-006870-f5w6fw6q 6557 4 external external JJ cord-006870-f5w6fw6q 6557 5 cooling cooling NN cord-006870-f5w6fw6q 6557 6 , , , cord-006870-f5w6fw6q 6557 7 peripheral peripheral JJ cord-006870-f5w6fw6q 6557 8 IV IV NNP cord-006870-f5w6fw6q 6557 9 cooling cooling NN cord-006870-f5w6fw6q 6557 10 , , , cord-006870-f5w6fw6q 6557 11 Tylenol Tylenol NNP cord-006870-f5w6fw6q 6557 12 and and CC cord-006870-f5w6fw6q 6557 13 NSAIDs NSAIDs NNPS cord-006870-f5w6fw6q 6557 14 were be VBD cord-006870-f5w6fw6q 6557 15 also also RB cord-006870-f5w6fw6q 6557 16 not not RB cord-006870-f5w6fw6q 6557 17 helpful helpful JJ cord-006870-f5w6fw6q 6557 18 . . . cord-006870-f5w6fw6q 6558 1 Fever Fever NNP cord-006870-f5w6fw6q 6558 2 responded respond VBD cord-006870-f5w6fw6q 6558 3 to to IN cord-006870-f5w6fw6q 6558 4 central central JJ cord-006870-f5w6fw6q 6558 5 Intravascular Intravascular NNP cord-006870-f5w6fw6q 6558 6 cooling cool VBG cord-006870-f5w6fw6q 6558 7 but but CC cord-006870-f5w6fw6q 6558 8 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6558 9 did do VBD cord-006870-f5w6fw6q 6558 10 not not RB cord-006870-f5w6fw6q 6558 11 . . . cord-006870-f5w6fw6q 6559 1 Several several JJ cord-006870-f5w6fw6q 6559 2 expert expert NN cord-006870-f5w6fw6q 6559 3 attempts attempt NNS cord-006870-f5w6fw6q 6559 4 of of IN cord-006870-f5w6fw6q 6559 5 LP lp NN cord-006870-f5w6fw6q 6559 6 and and CC cord-006870-f5w6fw6q 6559 7 shunt shunt NN cord-006870-f5w6fw6q 6559 8 tapping tapping NN cord-006870-f5w6fw6q 6559 9 failed fail VBD cord-006870-f5w6fw6q 6559 10 to to TO cord-006870-f5w6fw6q 6559 11 obtain obtain VB cord-006870-f5w6fw6q 6559 12 CSF CSF NNP cord-006870-f5w6fw6q 6559 13 . . . cord-006870-f5w6fw6q 6560 1 Brain brain NN cord-006870-f5w6fw6q 6560 2 imaging imaging NN cord-006870-f5w6fw6q 6560 3 showed show VBD cord-006870-f5w6fw6q 6560 4 bilateral bilateral JJ cord-006870-f5w6fw6q 6560 5 chronic chronic JJ cord-006870-f5w6fw6q 6560 6 symmetrical symmetrical JJ cord-006870-f5w6fw6q 6560 7 hygromas hygromas NNPS cord-006870-f5w6fw6q 6560 8 , , , cord-006870-f5w6fw6q 6560 9 diffuse diffuse VB cord-006870-f5w6fw6q 6560 10 pachy pachy NN cord-006870-f5w6fw6q 6560 11 - - HYPH cord-006870-f5w6fw6q 6560 12 meningeal meningeal JJ cord-006870-f5w6fw6q 6560 13 thickening thickening NN cord-006870-f5w6fw6q 6560 14 and and CC cord-006870-f5w6fw6q 6560 15 enhancement enhancement NN cord-006870-f5w6fw6q 6560 16 , , , cord-006870-f5w6fw6q 6560 17 slit slit NN cord-006870-f5w6fw6q 6560 18 - - HYPH cord-006870-f5w6fw6q 6560 19 like like JJ cord-006870-f5w6fw6q 6560 20 ventricles ventricle NNS cord-006870-f5w6fw6q 6560 21 and and CC cord-006870-f5w6fw6q 6560 22 slumping slump VBG cord-006870-f5w6fw6q 6560 23 of of IN cord-006870-f5w6fw6q 6560 24 the the DT cord-006870-f5w6fw6q 6560 25 midbrain midbrain NN cord-006870-f5w6fw6q 6560 26 with with IN cord-006870-f5w6fw6q 6560 27 closure closure NN cord-006870-f5w6fw6q 6560 28 of of IN cord-006870-f5w6fw6q 6560 29 the the DT cord-006870-f5w6fw6q 6560 30 mammillary mammillary JJ cord-006870-f5w6fw6q 6560 31 pontine pontine NNP cord-006870-f5w6fw6q 6560 32 distance distance NN cord-006870-f5w6fw6q 6560 33 . . . cord-006870-f5w6fw6q 6561 1 Following follow VBG cord-006870-f5w6fw6q 6561 2 shunt shunt NN cord-006870-f5w6fw6q 6561 3 setting set VBG cord-006870-f5w6fw6q 6561 4 adjustment adjustment NN cord-006870-f5w6fw6q 6561 5 , , , cord-006870-f5w6fw6q 6561 6 the the DT cord-006870-f5w6fw6q 6561 7 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6561 8 markedly markedly RB cord-006870-f5w6fw6q 6561 9 improved improve VBD cord-006870-f5w6fw6q 6561 10 and and CC cord-006870-f5w6fw6q 6561 11 the the DT cord-006870-f5w6fw6q 6561 12 fever fever NN cord-006870-f5w6fw6q 6561 13 did do VBD cord-006870-f5w6fw6q 6561 14 not not RB cord-006870-f5w6fw6q 6561 15 recur recur VB cord-006870-f5w6fw6q 6561 16 after after IN cord-006870-f5w6fw6q 6561 17 stopping stop VBG cord-006870-f5w6fw6q 6561 18 the the DT cord-006870-f5w6fw6q 6561 19 cooling cool VBG cord-006870-f5w6fw6q 6561 20 measures measure NNS cord-006870-f5w6fw6q 6561 21 and and CC cord-006870-f5w6fw6q 6561 22 antimicrobials antimicrobial NNS cord-006870-f5w6fw6q 6561 23 . . . cord-006870-f5w6fw6q 6562 1 Intracranial intracranial JJ cord-006870-f5w6fw6q 6562 2 hypotension hypotension NN cord-006870-f5w6fw6q 6562 3 might may MD cord-006870-f5w6fw6q 6562 4 present present VB cord-006870-f5w6fw6q 6562 5 with with IN cord-006870-f5w6fw6q 6562 6 hyperpyrexia hyperpyrexia NNP cord-006870-f5w6fw6q 6562 7 , , , cord-006870-f5w6fw6q 6562 8 likely likely RB cord-006870-f5w6fw6q 6562 9 secondary secondary JJ cord-006870-f5w6fw6q 6562 10 to to IN cord-006870-f5w6fw6q 6562 11 hypothalamic hypothalamic JJ cord-006870-f5w6fw6q 6562 12 dysfunction dysfunction NN cord-006870-f5w6fw6q 6562 13 . . . cord-006870-f5w6fw6q 6563 1 In in IN cord-006870-f5w6fw6q 6563 2 our -PRON- PRP$ cord-006870-f5w6fw6q 6563 3 case case NN cord-006870-f5w6fw6q 6563 4 , , , cord-006870-f5w6fw6q 6563 5 hyperpyrexia hyperpyrexia NNP cord-006870-f5w6fw6q 6563 6 was be VBD cord-006870-f5w6fw6q 6563 7 reversible reversible JJ cord-006870-f5w6fw6q 6563 8 as as IN cord-006870-f5w6fw6q 6563 9 the the DT cord-006870-f5w6fw6q 6563 10 intracranial intracranial JJ cord-006870-f5w6fw6q 6563 11 hypotension hypotension NN cord-006870-f5w6fw6q 6563 12 was be VBD cord-006870-f5w6fw6q 6563 13 emergently emergently RB cord-006870-f5w6fw6q 6563 14 treated treat VBN cord-006870-f5w6fw6q 6563 15 . . . cord-006870-f5w6fw6q 6564 1 Nevertheless nevertheless RB cord-006870-f5w6fw6q 6564 2 , , , cord-006870-f5w6fw6q 6564 3 spontaneous spontaneous JJ cord-006870-f5w6fw6q 6564 4 intracranial intracranial JJ cord-006870-f5w6fw6q 6564 5 hypotension hypotension NN cord-006870-f5w6fw6q 6564 6 might may MD cord-006870-f5w6fw6q 6564 7 be be VB cord-006870-f5w6fw6q 6564 8 difficult difficult JJ cord-006870-f5w6fw6q 6564 9 to to TO cord-006870-f5w6fw6q 6564 10 diagnose diagnose VB cord-006870-f5w6fw6q 6564 11 especially especially RB cord-006870-f5w6fw6q 6564 12 if if IN cord-006870-f5w6fw6q 6564 13 it -PRON- PRP cord-006870-f5w6fw6q 6564 14 presented present VBD cord-006870-f5w6fw6q 6564 15 with with IN cord-006870-f5w6fw6q 6564 16 non non JJ cord-006870-f5w6fw6q 6564 17 - - JJ cord-006870-f5w6fw6q 6564 18 classical classical JJ cord-006870-f5w6fw6q 6564 19 symptoms symptom NNS cord-006870-f5w6fw6q 6564 20 like like IN cord-006870-f5w6fw6q 6564 21 fever fever NN cord-006870-f5w6fw6q 6564 22 . . . cord-006870-f5w6fw6q 6565 1 Complex complex JJ cord-006870-f5w6fw6q 6565 2 emotions emotion NNS cord-006870-f5w6fw6q 6565 3 about about IN cord-006870-f5w6fw6q 6565 4 critical critical JJ cord-006870-f5w6fw6q 6565 5 illness illness NN cord-006870-f5w6fw6q 6565 6 can can MD cord-006870-f5w6fw6q 6565 7 affect affect VB cord-006870-f5w6fw6q 6565 8 families family NNS cord-006870-f5w6fw6q 6565 9 in in IN cord-006870-f5w6fw6q 6565 10 the the DT cord-006870-f5w6fw6q 6565 11 ICU ICU NNP cord-006870-f5w6fw6q 6565 12 . . . cord-006870-f5w6fw6q 6566 1 Rightfully rightfully RB cord-006870-f5w6fw6q 6566 2 , , , cord-006870-f5w6fw6q 6566 3 we -PRON- PRP cord-006870-f5w6fw6q 6566 4 put put VBD cord-006870-f5w6fw6q 6566 5 focus focus NN cord-006870-f5w6fw6q 6566 6 on on IN cord-006870-f5w6fw6q 6566 7 how how WRB cord-006870-f5w6fw6q 6566 8 they -PRON- PRP cord-006870-f5w6fw6q 6566 9 are be VBP cord-006870-f5w6fw6q 6566 10 impacted impact VBN cord-006870-f5w6fw6q 6566 11 , , , cord-006870-f5w6fw6q 6566 12 but but CC cord-006870-f5w6fw6q 6566 13 we -PRON- PRP cord-006870-f5w6fw6q 6566 14 also also RB cord-006870-f5w6fw6q 6566 15 need need VBP cord-006870-f5w6fw6q 6566 16 to to TO cord-006870-f5w6fw6q 6566 17 pay pay VB cord-006870-f5w6fw6q 6566 18 attention attention NN cord-006870-f5w6fw6q 6566 19 to to IN cord-006870-f5w6fw6q 6566 20 how how WRB cord-006870-f5w6fw6q 6566 21 it -PRON- PRP cord-006870-f5w6fw6q 6566 22 can can MD cord-006870-f5w6fw6q 6566 23 affect affect VB cord-006870-f5w6fw6q 6566 24 providers provider NNS cord-006870-f5w6fw6q 6566 25 and and CC cord-006870-f5w6fw6q 6566 26 our -PRON- PRP$ cord-006870-f5w6fw6q 6566 27 decision decision NN cord-006870-f5w6fw6q 6566 28 making making NN cord-006870-f5w6fw6q 6566 29 . . . cord-006870-f5w6fw6q 6567 1 A a DT cord-006870-f5w6fw6q 6567 2 poignant poignant JJ cord-006870-f5w6fw6q 6567 3 case case NN cord-006870-f5w6fw6q 6567 4 from from IN cord-006870-f5w6fw6q 6567 5 my -PRON- PRP$ cord-006870-f5w6fw6q 6567 6 training training NN cord-006870-f5w6fw6q 6567 7 was be VBD cord-006870-f5w6fw6q 6567 8 a a DT cord-006870-f5w6fw6q 6567 9 15-year 15-year JJ cord-006870-f5w6fw6q 6567 10 - - HYPH cord-006870-f5w6fw6q 6567 11 old old JJ cord-006870-f5w6fw6q 6567 12 girl girl NN cord-006870-f5w6fw6q 6567 13 struggling struggle VBG cord-006870-f5w6fw6q 6567 14 with with IN cord-006870-f5w6fw6q 6567 15 lupus lupus NN cord-006870-f5w6fw6q 6567 16 . . . cord-006870-f5w6fw6q 6568 1 She -PRON- PRP cord-006870-f5w6fw6q 6568 2 had have VBD cord-006870-f5w6fw6q 6568 3 now now RB cord-006870-f5w6fw6q 6568 4 developed develop VBN cord-006870-f5w6fw6q 6568 5 lupus lupus NN cord-006870-f5w6fw6q 6568 6 cerebritis cerebritis NNP cord-006870-f5w6fw6q 6568 7 and and CC cord-006870-f5w6fw6q 6568 8 had have VBD cord-006870-f5w6fw6q 6568 9 massive massive JJ cord-006870-f5w6fw6q 6568 10 intracranial intracranial JJ cord-006870-f5w6fw6q 6568 11 hemorrhages hemorrhage NNS cord-006870-f5w6fw6q 6568 12 . . . cord-006870-f5w6fw6q 6569 1 Despite despite IN cord-006870-f5w6fw6q 6569 2 aggressive aggressive JJ cord-006870-f5w6fw6q 6569 3 efforts effort NNS cord-006870-f5w6fw6q 6569 4 to to TO cord-006870-f5w6fw6q 6569 5 manage manage VB cord-006870-f5w6fw6q 6569 6 cerebral cerebral JJ cord-006870-f5w6fw6q 6569 7 edema edema NN cord-006870-f5w6fw6q 6569 8 , , , cord-006870-f5w6fw6q 6569 9 she -PRON- PRP cord-006870-f5w6fw6q 6569 10 repeatedly repeatedly RB cord-006870-f5w6fw6q 6569 11 herniated herniate VBD cord-006870-f5w6fw6q 6569 12 brain brain NN cord-006870-f5w6fw6q 6569 13 matter matter NN cord-006870-f5w6fw6q 6569 14 out out IN cord-006870-f5w6fw6q 6569 15 of of IN cord-006870-f5w6fw6q 6569 16 old old JJ cord-006870-f5w6fw6q 6569 17 craniotomy craniotomy NN cord-006870-f5w6fw6q 6569 18 scars scar NNS cord-006870-f5w6fw6q 6569 19 with with IN cord-006870-f5w6fw6q 6569 20 incredible incredible JJ cord-006870-f5w6fw6q 6569 21 force force NN cord-006870-f5w6fw6q 6569 22 . . . cord-006870-f5w6fw6q 6570 1 It -PRON- PRP cord-006870-f5w6fw6q 6570 2 was be VBD cord-006870-f5w6fw6q 6570 3 the the DT cord-006870-f5w6fw6q 6570 4 most most RBS cord-006870-f5w6fw6q 6570 5 horrifying horrifying JJ cord-006870-f5w6fw6q 6570 6 thing thing NN cord-006870-f5w6fw6q 6570 7 I -PRON- PRP cord-006870-f5w6fw6q 6570 8 've have VB cord-006870-f5w6fw6q 6570 9 ever ever RB cord-006870-f5w6fw6q 6570 10 seen see VBN cord-006870-f5w6fw6q 6570 11 . . . cord-006870-f5w6fw6q 6571 1 Other other JJ cord-006870-f5w6fw6q 6571 2 organs organ NNS cord-006870-f5w6fw6q 6571 3 were be VBD cord-006870-f5w6fw6q 6571 4 also also RB cord-006870-f5w6fw6q 6571 5 failing fail VBG cord-006870-f5w6fw6q 6571 6 , , , cord-006870-f5w6fw6q 6571 7 with with IN cord-006870-f5w6fw6q 6571 8 four four CD cord-006870-f5w6fw6q 6571 9 consulting consulting NN cord-006870-f5w6fw6q 6571 10 services service NNS cord-006870-f5w6fw6q 6571 11 working work VBG cord-006870-f5w6fw6q 6571 12 to to TO cord-006870-f5w6fw6q 6571 13 salvage salvage VB cord-006870-f5w6fw6q 6571 14 them -PRON- PRP cord-006870-f5w6fw6q 6571 15 unsuccessfully unsuccessfully RB cord-006870-f5w6fw6q 6571 16 , , , cord-006870-f5w6fw6q 6571 17 prompting prompt VBG cord-006870-f5w6fw6q 6571 18 numerous numerous JJ cord-006870-f5w6fw6q 6571 19 procedures procedure NNS cord-006870-f5w6fw6q 6571 20 . . . cord-006870-f5w6fw6q 6572 1 This this DT cord-006870-f5w6fw6q 6572 2 went go VBD cord-006870-f5w6fw6q 6572 3 on on RP cord-006870-f5w6fw6q 6572 4 for for IN cord-006870-f5w6fw6q 6572 5 a a DT cord-006870-f5w6fw6q 6572 6 month month NN cord-006870-f5w6fw6q 6572 7 . . . cord-006870-f5w6fw6q 6573 1 The the DT cord-006870-f5w6fw6q 6573 2 therapies therapy NNS cord-006870-f5w6fw6q 6573 3 that that WDT cord-006870-f5w6fw6q 6573 4 we -PRON- PRP cord-006870-f5w6fw6q 6573 5 can can MD cord-006870-f5w6fw6q 6573 6 offer offer VB cord-006870-f5w6fw6q 6573 7 have have VB cord-006870-f5w6fw6q 6573 8 limits limit NNS cord-006870-f5w6fw6q 6573 9 from from IN cord-006870-f5w6fw6q 6573 10 a a DT cord-006870-f5w6fw6q 6573 11 physiological physiological JJ cord-006870-f5w6fw6q 6573 12 standpoint standpoint NN cord-006870-f5w6fw6q 6573 13 which which WDT cord-006870-f5w6fw6q 6573 14 we -PRON- PRP cord-006870-f5w6fw6q 6573 15 must must MD cord-006870-f5w6fw6q 6573 16 recognize recognize VB cord-006870-f5w6fw6q 6573 17 and and CC cord-006870-f5w6fw6q 6573 18 respect respect VB cord-006870-f5w6fw6q 6573 19 . . . cord-006870-f5w6fw6q 6574 1 We -PRON- PRP cord-006870-f5w6fw6q 6574 2 struggle struggle VBP cord-006870-f5w6fw6q 6574 3 with with IN cord-006870-f5w6fw6q 6574 4 reconciling reconcile VBG cord-006870-f5w6fw6q 6574 5 the the DT cord-006870-f5w6fw6q 6574 6 interventions intervention NNS cord-006870-f5w6fw6q 6574 7 we -PRON- PRP cord-006870-f5w6fw6q 6574 8 feel feel VBP cord-006870-f5w6fw6q 6574 9 compelled compel VBN cord-006870-f5w6fw6q 6574 10 to to TO cord-006870-f5w6fw6q 6574 11 implement implement VB cord-006870-f5w6fw6q 6574 12 versus versus IN cord-006870-f5w6fw6q 6574 13 what what WP cord-006870-f5w6fw6q 6574 14 is be VBZ cord-006870-f5w6fw6q 6574 15 realistic realistic JJ cord-006870-f5w6fw6q 6574 16 . . . cord-006870-f5w6fw6q 6575 1 I -PRON- PRP cord-006870-f5w6fw6q 6575 2 remembered remember VBD cord-006870-f5w6fw6q 6575 3 the the DT cord-006870-f5w6fw6q 6575 4 most most RBS cord-006870-f5w6fw6q 6575 5 valuable valuable JJ cord-006870-f5w6fw6q 6575 6 advice advice NN cord-006870-f5w6fw6q 6575 7 that that WDT cord-006870-f5w6fw6q 6575 8 I -PRON- PRP cord-006870-f5w6fw6q 6575 9 once once RB cord-006870-f5w6fw6q 6575 10 received receive VBD cord-006870-f5w6fw6q 6575 11 : : : cord-006870-f5w6fw6q 6575 12 " " `` cord-006870-f5w6fw6q 6575 13 only only RB cord-006870-f5w6fw6q 6575 14 do do VB cord-006870-f5w6fw6q 6575 15 something something NN cord-006870-f5w6fw6q 6575 16 to to IN cord-006870-f5w6fw6q 6575 17 someone someone NN cord-006870-f5w6fw6q 6575 18 if if IN cord-006870-f5w6fw6q 6575 19 it -PRON- PRP cord-006870-f5w6fw6q 6575 20 does do VBZ cord-006870-f5w6fw6q 6575 21 The the DT cord-006870-f5w6fw6q 6575 22 complexity complexity NN cord-006870-f5w6fw6q 6575 23 of of IN cord-006870-f5w6fw6q 6575 24 the the DT cord-006870-f5w6fw6q 6575 25 neuro neuro NNP cord-006870-f5w6fw6q 6575 26 ICU ICU NNP cord-006870-f5w6fw6q 6575 27 is be VBZ cord-006870-f5w6fw6q 6575 28 amplified amplify VBN cord-006870-f5w6fw6q 6575 29 by by IN cord-006870-f5w6fw6q 6575 30 the the DT cord-006870-f5w6fw6q 6575 31 nature nature NN cord-006870-f5w6fw6q 6575 32 of of IN cord-006870-f5w6fw6q 6575 33 intracranial intracranial JJ cord-006870-f5w6fw6q 6575 34 catastrophes catastrophe NNS cord-006870-f5w6fw6q 6575 35 and and CC cord-006870-f5w6fw6q 6575 36 poor poor JJ cord-006870-f5w6fw6q 6575 37 recovery recovery NN cord-006870-f5w6fw6q 6575 38 ( ( -LRB- cord-006870-f5w6fw6q 6575 39 in in IN cord-006870-f5w6fw6q 6575 40 contrast contrast NN cord-006870-f5w6fw6q 6575 41 to to IN cord-006870-f5w6fw6q 6575 42 pure pure JJ cord-006870-f5w6fw6q 6575 43 medical medical JJ cord-006870-f5w6fw6q 6575 44 illness illness NN cord-006870-f5w6fw6q 6575 45 ) ) -RRB- cord-006870-f5w6fw6q 6575 46 . . . cord-006870-f5w6fw6q 6576 1 Providers provider NNS cord-006870-f5w6fw6q 6576 2 cling cling VBP cord-006870-f5w6fw6q 6576 3 to to IN cord-006870-f5w6fw6q 6576 4 what what WP cord-006870-f5w6fw6q 6576 5 is be VBZ cord-006870-f5w6fw6q 6576 6 technically technically RB cord-006870-f5w6fw6q 6576 7 indicated indicate VBN cord-006870-f5w6fw6q 6576 8 while while IN cord-006870-f5w6fw6q 6576 9 families family NNS cord-006870-f5w6fw6q 6576 10 cling cling VBP cord-006870-f5w6fw6q 6576 11 to to TO cord-006870-f5w6fw6q 6576 12 hope hope VB cord-006870-f5w6fw6q 6576 13 , , , cord-006870-f5w6fw6q 6576 14 but but CC cord-006870-f5w6fw6q 6576 15 neither neither DT cord-006870-f5w6fw6q 6576 16 is be VBZ cord-006870-f5w6fw6q 6576 17 enough enough JJ cord-006870-f5w6fw6q 6576 18 and and CC cord-006870-f5w6fw6q 6576 19 concurrently concurrently RB cord-006870-f5w6fw6q 6576 20 too too RB cord-006870-f5w6fw6q 6576 21 much much JJ cord-006870-f5w6fw6q 6576 22 . . . cord-006870-f5w6fw6q 6577 1 We -PRON- PRP cord-006870-f5w6fw6q 6577 2 lose lose VBP cord-006870-f5w6fw6q 6577 3 our -PRON- PRP$ cord-006870-f5w6fw6q 6577 4 autonomy autonomy NN cord-006870-f5w6fw6q 6577 5 to to IN cord-006870-f5w6fw6q 6577 6 grieving grieve VBG cord-006870-f5w6fw6q 6577 7 families family NNS cord-006870-f5w6fw6q 6577 8 telling tell VBG cord-006870-f5w6fw6q 6577 9 us -PRON- PRP cord-006870-f5w6fw6q 6577 10 to to TO cord-006870-f5w6fw6q 6577 11 " " `` cord-006870-f5w6fw6q 6577 12 do do VB cord-006870-f5w6fw6q 6577 13 everything everything NN cord-006870-f5w6fw6q 6577 14 " " `` cord-006870-f5w6fw6q 6577 15 losing lose VBG cord-006870-f5w6fw6q 6577 16 sight sight NN cord-006870-f5w6fw6q 6577 17 of of IN cord-006870-f5w6fw6q 6577 18 the the DT cord-006870-f5w6fw6q 6577 19 bigger big JJR cord-006870-f5w6fw6q 6577 20 picture picture NN cord-006870-f5w6fw6q 6577 21 . . . cord-006870-f5w6fw6q 6578 1 We -PRON- PRP cord-006870-f5w6fw6q 6578 2 lose lose VBP cord-006870-f5w6fw6q 6578 3 our -PRON- PRP$ cord-006870-f5w6fw6q 6578 4 autonomy autonomy NN cord-006870-f5w6fw6q 6578 5 to to IN cord-006870-f5w6fw6q 6578 6 one one CD cord-006870-f5w6fw6q 6578 7 another another DT cord-006870-f5w6fw6q 6578 8 by by IN cord-006870-f5w6fw6q 6578 9 pushing push VBG cord-006870-f5w6fw6q 6578 10 onwards onwards RB cord-006870-f5w6fw6q 6578 11 , , , cord-006870-f5w6fw6q 6578 12 which which WDT cord-006870-f5w6fw6q 6578 13 can can MD cord-006870-f5w6fw6q 6578 14 unintentionally unintentionally RB cord-006870-f5w6fw6q 6578 15 push push VB cord-006870-f5w6fw6q 6578 16 each each DT cord-006870-f5w6fw6q 6578 17 other other JJ cord-006870-f5w6fw6q 6578 18 into into IN cord-006870-f5w6fw6q 6578 19 the the DT cord-006870-f5w6fw6q 6578 20 territory territory NN cord-006870-f5w6fw6q 6578 21 of of IN cord-006870-f5w6fw6q 6578 22 doing do VBG cord-006870-f5w6fw6q 6578 23 more more JJR cord-006870-f5w6fw6q 6578 24 harm harm NN cord-006870-f5w6fw6q 6578 25 than than IN cord-006870-f5w6fw6q 6578 26 good good JJ cord-006870-f5w6fw6q 6578 27 . . . cord-006870-f5w6fw6q 6579 1 something something NN cord-006870-f5w6fw6q 6579 2 for for IN cord-006870-f5w6fw6q 6579 3 them -PRON- PRP cord-006870-f5w6fw6q 6579 4 " " '' cord-006870-f5w6fw6q 6579 5 . . . cord-006870-f5w6fw6q 6580 1 All all DT cord-006870-f5w6fw6q 6580 2 services service NNS cord-006870-f5w6fw6q 6580 3 began begin VBD cord-006870-f5w6fw6q 6580 4 to to TO cord-006870-f5w6fw6q 6580 5 share share VB cord-006870-f5w6fw6q 6580 6 this this DT cord-006870-f5w6fw6q 6580 7 view view NN cord-006870-f5w6fw6q 6580 8 , , , cord-006870-f5w6fw6q 6580 9 thus thus RB cord-006870-f5w6fw6q 6580 10 slowly slowly RB cord-006870-f5w6fw6q 6580 11 dialysis dialysis NN cord-006870-f5w6fw6q 6580 12 , , , cord-006870-f5w6fw6q 6580 13 steroids steroid NNS cord-006870-f5w6fw6q 6580 14 and and CC cord-006870-f5w6fw6q 6580 15 immunosuppression immunosuppression NN cord-006870-f5w6fw6q 6580 16 stopped stop VBD cord-006870-f5w6fw6q 6580 17 . . . cord-006870-f5w6fw6q 6581 1 Eventually eventually RB cord-006870-f5w6fw6q 6581 2 , , , cord-006870-f5w6fw6q 6581 3 her -PRON- PRP$ cord-006870-f5w6fw6q 6581 4 heart heart NN cord-006870-f5w6fw6q 6581 5 stopped stop VBD cord-006870-f5w6fw6q 6581 6 . . . cord-006870-f5w6fw6q 6582 1 My -PRON- PRP$ cord-006870-f5w6fw6q 6582 2 experiences experience NNS cord-006870-f5w6fw6q 6582 3 have have VBP cord-006870-f5w6fw6q 6582 4 reiterated reiterate VBN cord-006870-f5w6fw6q 6582 5 a a DT cord-006870-f5w6fw6q 6582 6 simple simple JJ cord-006870-f5w6fw6q 6582 7 paradigm paradigm NN cord-006870-f5w6fw6q 6582 8 : : : cord-006870-f5w6fw6q 6582 9 to to TO cord-006870-f5w6fw6q 6582 10 do do VB cord-006870-f5w6fw6q 6582 11 no no DT cord-006870-f5w6fw6q 6582 12 harm harm NN cord-006870-f5w6fw6q 6582 13 . . . cord-006870-f5w6fw6q 6583 1 Through through IN cord-006870-f5w6fw6q 6583 2 this this DT cord-006870-f5w6fw6q 6583 3 , , , cord-006870-f5w6fw6q 6583 4 I -PRON- PRP cord-006870-f5w6fw6q 6583 5 can can MD cord-006870-f5w6fw6q 6583 6 empower empower VB cord-006870-f5w6fw6q 6583 7 myself -PRON- PRP cord-006870-f5w6fw6q 6583 8 to to TO cord-006870-f5w6fw6q 6583 9 take take VB cord-006870-f5w6fw6q 6583 10 control control NN cord-006870-f5w6fw6q 6583 11 of of IN cord-006870-f5w6fw6q 6583 12 each each DT cord-006870-f5w6fw6q 6583 13 situation situation NN cord-006870-f5w6fw6q 6583 14 by by IN cord-006870-f5w6fw6q 6583 15 first first JJ cord-006870-f5w6fw6q 6583 16 taking take VBG cord-006870-f5w6fw6q 6583 17 control control NN cord-006870-f5w6fw6q 6583 18 of of IN cord-006870-f5w6fw6q 6583 19 myself -PRON- PRP cord-006870-f5w6fw6q 6583 20 . . . cord-006870-f5w6fw6q 6584 1 We -PRON- PRP cord-006870-f5w6fw6q 6584 2 report report VBP cord-006870-f5w6fw6q 6584 3 a a DT cord-006870-f5w6fw6q 6584 4 case case NN cord-006870-f5w6fw6q 6584 5 of of IN cord-006870-f5w6fw6q 6584 6 an an DT cord-006870-f5w6fw6q 6584 7 HIV HIV NNP cord-006870-f5w6fw6q 6584 8 positive positive JJ cord-006870-f5w6fw6q 6584 9 patient patient NN cord-006870-f5w6fw6q 6584 10 who who WP cord-006870-f5w6fw6q 6584 11 presented present VBD cord-006870-f5w6fw6q 6584 12 with with IN cord-006870-f5w6fw6q 6584 13 Cryptococcus Cryptococcus NNP cord-006870-f5w6fw6q 6584 14 gattii gattii NNP cord-006870-f5w6fw6q 6584 15 meningitis meningitis NN cord-006870-f5w6fw6q 6584 16 who who WP cord-006870-f5w6fw6q 6584 17 then then RB cord-006870-f5w6fw6q 6584 18 developed develop VBD cord-006870-f5w6fw6q 6584 19 acute acute JJ cord-006870-f5w6fw6q 6584 20 respiratory respiratory JJ cord-006870-f5w6fw6q 6584 21 distress distress NN cord-006870-f5w6fw6q 6584 22 syndrome syndrome NN cord-006870-f5w6fw6q 6584 23 ( ( -LRB- cord-006870-f5w6fw6q 6584 24 ARDS ARDS NNP cord-006870-f5w6fw6q 6584 25 ) ) -RRB- cord-006870-f5w6fw6q 6584 26 secondary secondary JJ cord-006870-f5w6fw6q 6584 27 to to IN cord-006870-f5w6fw6q 6584 28 Pneumocystis Pneumocystis NNP cord-006870-f5w6fw6q 6584 29 jirovecii jirovecii NNP cord-006870-f5w6fw6q 6584 30 pneumonia pneumonia NN cord-006870-f5w6fw6q 6585 1 ( ( -LRB- cord-006870-f5w6fw6q 6585 2 PJP PJP NNP cord-006870-f5w6fw6q 6585 3 ) ) -RRB- cord-006870-f5w6fw6q 6585 4 that that WDT cord-006870-f5w6fw6q 6585 5 required require VBD cord-006870-f5w6fw6q 6585 6 ECMO ECMO NNP cord-006870-f5w6fw6q 6585 7 support support NN cord-006870-f5w6fw6q 6585 8 . . . cord-006870-f5w6fw6q 6586 1 ARDS ARDS NNP cord-006870-f5w6fw6q 6586 2 in in IN cord-006870-f5w6fw6q 6586 3 immunocompromised immunocompromised JJ cord-006870-f5w6fw6q 6586 4 HIV HIV NNP cord-006870-f5w6fw6q 6586 5 positive positive JJ cord-006870-f5w6fw6q 6586 6 patients patient NNS cord-006870-f5w6fw6q 6586 7 is be VBZ cord-006870-f5w6fw6q 6586 8 associated associate VBN cord-006870-f5w6fw6q 6586 9 with with IN cord-006870-f5w6fw6q 6586 10 extremely extremely RB cord-006870-f5w6fw6q 6586 11 high high JJ cord-006870-f5w6fw6q 6586 12 mortality mortality NN cord-006870-f5w6fw6q 6586 13 . . . cord-006870-f5w6fw6q 6587 1 ECMO ECMO NNP cord-006870-f5w6fw6q 6587 2 can can MD cord-006870-f5w6fw6q 6587 3 improve improve VB cord-006870-f5w6fw6q 6587 4 oxygenation oxygenation NN cord-006870-f5w6fw6q 6587 5 in in IN cord-006870-f5w6fw6q 6587 6 patients patient NNS cord-006870-f5w6fw6q 6587 7 without without IN cord-006870-f5w6fw6q 6587 8 increasing increase VBG cord-006870-f5w6fw6q 6587 9 alveolar alveolar JJ cord-006870-f5w6fw6q 6587 10 pressure pressure NN cord-006870-f5w6fw6q 6587 11 and and CC cord-006870-f5w6fw6q 6587 12 therefore therefore RB cord-006870-f5w6fw6q 6587 13 avoid avoid VB cord-006870-f5w6fw6q 6587 14 mechanical mechanical JJ cord-006870-f5w6fw6q 6587 15 lung lung NN cord-006870-f5w6fw6q 6587 16 damage damage NN cord-006870-f5w6fw6q 6587 17 with with IN cord-006870-f5w6fw6q 6587 18 ventilation ventilation NN cord-006870-f5w6fw6q 6587 19 . . . cord-006870-f5w6fw6q 6588 1 We -PRON- PRP cord-006870-f5w6fw6q 6588 2 present present VBP cord-006870-f5w6fw6q 6588 3 a a DT cord-006870-f5w6fw6q 6588 4 patient patient NN cord-006870-f5w6fw6q 6588 5 with with IN cord-006870-f5w6fw6q 6588 6 newly newly RB cord-006870-f5w6fw6q 6588 7 diagnosed diagnose VBN cord-006870-f5w6fw6q 6588 8 AIDS AIDS NNP cord-006870-f5w6fw6q 6588 9 with with IN cord-006870-f5w6fw6q 6588 10 Cryptococcus Cryptococcus NNP cord-006870-f5w6fw6q 6588 11 gattii gattii NNP cord-006870-f5w6fw6q 6588 12 meningitis meningitis NN cord-006870-f5w6fw6q 6588 13 and and CC cord-006870-f5w6fw6q 6588 14 course course NN cord-006870-f5w6fw6q 6588 15 complicated complicate VBN cord-006870-f5w6fw6q 6588 16 by by IN cord-006870-f5w6fw6q 6588 17 PJP PJP NNP cord-006870-f5w6fw6q 6588 18 that that WDT cord-006870-f5w6fw6q 6588 19 progressed progress VBD cord-006870-f5w6fw6q 6588 20 to to IN cord-006870-f5w6fw6q 6588 21 severe severe JJ cord-006870-f5w6fw6q 6588 22 acute acute JJ cord-006870-f5w6fw6q 6588 23 respiratory respiratory JJ cord-006870-f5w6fw6q 6588 24 distress distress NN cord-006870-f5w6fw6q 6588 25 syndrome syndrome NN cord-006870-f5w6fw6q 6588 26 ( ( -LRB- cord-006870-f5w6fw6q 6588 27 ARDS ARDS NNP cord-006870-f5w6fw6q 6588 28 ) ) -RRB- cord-006870-f5w6fw6q 6588 29 for for IN cord-006870-f5w6fw6q 6588 30 which which WDT cord-006870-f5w6fw6q 6588 31 veno veno NNP cord-006870-f5w6fw6q 6588 32 - - HYPH cord-006870-f5w6fw6q 6588 33 venous venous JJ cord-006870-f5w6fw6q 6588 34 ECMO ECMO NNP cord-006870-f5w6fw6q 6588 35 was be VBD cord-006870-f5w6fw6q 6588 36 initiated initiate VBN cord-006870-f5w6fw6q 6588 37 . . . cord-006870-f5w6fw6q 6589 1 Patient Patient NNP cord-006870-f5w6fw6q 6589 2 is be VBZ cord-006870-f5w6fw6q 6589 3 a a DT cord-006870-f5w6fw6q 6589 4 27year 27year CD cord-006870-f5w6fw6q 6589 5 old old JJ cord-006870-f5w6fw6q 6589 6 male male NN cord-006870-f5w6fw6q 6589 7 who who WP cord-006870-f5w6fw6q 6589 8 presented present VBD cord-006870-f5w6fw6q 6589 9 to to IN cord-006870-f5w6fw6q 6589 10 the the DT cord-006870-f5w6fw6q 6589 11 emergency emergency NN cord-006870-f5w6fw6q 6589 12 department department NN cord-006870-f5w6fw6q 6589 13 with with IN cord-006870-f5w6fw6q 6589 14 new new JJ cord-006870-f5w6fw6q 6589 15 onset onset NN cord-006870-f5w6fw6q 6589 16 seizures seizure NNS cord-006870-f5w6fw6q 6589 17 . . . cord-006870-f5w6fw6q 6590 1 Lumbar lumbar JJ cord-006870-f5w6fw6q 6590 2 puncture puncture NN cord-006870-f5w6fw6q 6590 3 in in IN cord-006870-f5w6fw6q 6590 4 the the DT cord-006870-f5w6fw6q 6590 5 ED ED NNP cord-006870-f5w6fw6q 6590 6 overflowed overflow VBD cord-006870-f5w6fw6q 6590 7 the the DT cord-006870-f5w6fw6q 6590 8 manometer manometer NN cord-006870-f5w6fw6q 6590 9 and and CC cord-006870-f5w6fw6q 6590 10 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6590 11 WBC WBC NNP cord-006870-f5w6fw6q 6590 12 62 62 CD cord-006870-f5w6fw6q 6590 13 , , , cord-006870-f5w6fw6q 6590 14 RBC RBC NNP cord-006870-f5w6fw6q 6590 15 610 610 CD cord-006870-f5w6fw6q 6590 16 , , , cord-006870-f5w6fw6q 6590 17 protein protein NN cord-006870-f5w6fw6q 6590 18 41 41 CD cord-006870-f5w6fw6q 6590 19 , , , cord-006870-f5w6fw6q 6590 20 glucose glucose VBG cord-006870-f5w6fw6q 6590 21 51 51 CD cord-006870-f5w6fw6q 6590 22 , , , cord-006870-f5w6fw6q 6590 23 positive positive JJ cord-006870-f5w6fw6q 6590 24 yeast yeast NN cord-006870-f5w6fw6q 6590 25 gram gram NN cord-006870-f5w6fw6q 6590 26 stain stain NN cord-006870-f5w6fw6q 6590 27 positive positive JJ cord-006870-f5w6fw6q 6590 28 for for IN cord-006870-f5w6fw6q 6590 29 yeast yeast NN cord-006870-f5w6fw6q 6590 30 with with IN cord-006870-f5w6fw6q 6590 31 PCR PCR NNP cord-006870-f5w6fw6q 6590 32 and and CC cord-006870-f5w6fw6q 6590 33 Ag Ag NNP cord-006870-f5w6fw6q 6590 34 positive positive JJ cord-006870-f5w6fw6q 6590 35 . . . cord-006870-f5w6fw6q 6591 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6591 2 cultures culture NNS cord-006870-f5w6fw6q 6591 3 later later RB cord-006870-f5w6fw6q 6591 4 grew grow VBD cord-006870-f5w6fw6q 6591 5 out out RP cord-006870-f5w6fw6q 6591 6 Cryptoccoccus Cryptoccoccus NNP cord-006870-f5w6fw6q 6591 7 gattii gattii NNP cord-006870-f5w6fw6q 6591 8 . . . cord-006870-f5w6fw6q 6592 1 He -PRON- PRP cord-006870-f5w6fw6q 6592 2 was be VBD cord-006870-f5w6fw6q 6592 3 admitted admit VBN cord-006870-f5w6fw6q 6592 4 to to IN cord-006870-f5w6fw6q 6592 5 the the DT cord-006870-f5w6fw6q 6592 6 NSICU NSICU NNP cord-006870-f5w6fw6q 6592 7 and and CC cord-006870-f5w6fw6q 6592 8 we -PRON- PRP cord-006870-f5w6fw6q 6592 9 placed place VBD cord-006870-f5w6fw6q 6592 10 a a DT cord-006870-f5w6fw6q 6592 11 lumbar lumbar NN cord-006870-f5w6fw6q 6592 12 drain drain NN cord-006870-f5w6fw6q 6592 13 and and CC cord-006870-f5w6fw6q 6592 14 an an DT cord-006870-f5w6fw6q 6592 15 intraparenchymal intraparenchymal JJ cord-006870-f5w6fw6q 6592 16 IPC IPC NNP cord-006870-f5w6fw6q 6592 17 monitor monitor NN cord-006870-f5w6fw6q 6592 18 that that WDT cord-006870-f5w6fw6q 6592 19 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6592 20 elevated elevated JJ cord-006870-f5w6fw6q 6592 21 ICPs icp NNS cord-006870-f5w6fw6q 6592 22 to to IN cord-006870-f5w6fw6q 6592 23 the the DT cord-006870-f5w6fw6q 6592 24 60 60 CD cord-006870-f5w6fw6q 6592 25 - - SYM cord-006870-f5w6fw6q 6592 26 80mmH20 80mmh20 CD cord-006870-f5w6fw6q 6592 27 but but CC cord-006870-f5w6fw6q 6592 28 improved improve VBN cord-006870-f5w6fw6q 6592 29 with with IN cord-006870-f5w6fw6q 6592 30 drainage drainage NN cord-006870-f5w6fw6q 6592 31 . . . cord-006870-f5w6fw6q 6593 1 The the DT cord-006870-f5w6fw6q 6593 2 day day NN cord-006870-f5w6fw6q 6593 3 of of IN cord-006870-f5w6fw6q 6593 4 admission admission NN cord-006870-f5w6fw6q 6593 5 he -PRON- PRP cord-006870-f5w6fw6q 6593 6 acutely acutely RB cord-006870-f5w6fw6q 6593 7 desaturated desaturate VBD cord-006870-f5w6fw6q 6593 8 and and CC cord-006870-f5w6fw6q 6593 9 required require VBN cord-006870-f5w6fw6q 6593 10 emergent emergent JJ cord-006870-f5w6fw6q 6593 11 endotracheal endotracheal NN cord-006870-f5w6fw6q 6593 12 intubation intubation NN cord-006870-f5w6fw6q 6593 13 . . . cord-006870-f5w6fw6q 6594 1 Chest chest NN cord-006870-f5w6fw6q 6594 2 x x NN cord-006870-f5w6fw6q 6594 3 - - NN cord-006870-f5w6fw6q 6594 4 ray ray NN cord-006870-f5w6fw6q 6594 5 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6594 6 bilateral bilateral JJ cord-006870-f5w6fw6q 6594 7 infiltrates infiltrate NNS cord-006870-f5w6fw6q 6594 8 . . . cord-006870-f5w6fw6q 6595 1 BAL BAL NNP cord-006870-f5w6fw6q 6595 2 was be VBD cord-006870-f5w6fw6q 6595 3 positive positive JJ cord-006870-f5w6fw6q 6595 4 for for IN cord-006870-f5w6fw6q 6595 5 PJ PJ NNP cord-006870-f5w6fw6q 6595 6 . . . cord-006870-f5w6fw6q 6596 1 Five five CD cord-006870-f5w6fw6q 6596 2 days day NNS cord-006870-f5w6fw6q 6596 3 following follow VBG cord-006870-f5w6fw6q 6596 4 presentation presentation NN cord-006870-f5w6fw6q 6596 5 and and CC cord-006870-f5w6fw6q 6596 6 respiratory respiratory JJ cord-006870-f5w6fw6q 6596 7 failure failure NN cord-006870-f5w6fw6q 6596 8 he -PRON- PRP cord-006870-f5w6fw6q 6596 9 was be VBD cord-006870-f5w6fw6q 6596 10 started start VBN cord-006870-f5w6fw6q 6596 11 on on IN cord-006870-f5w6fw6q 6596 12 veno veno NNP cord-006870-f5w6fw6q 6596 13 - - HYPH cord-006870-f5w6fw6q 6596 14 venous venous JJ cord-006870-f5w6fw6q 6596 15 ECMO ECMO NNP cord-006870-f5w6fw6q 6596 16 . . . cord-006870-f5w6fw6q 6597 1 Two two CD cord-006870-f5w6fw6q 6597 2 days day NNS cord-006870-f5w6fw6q 6597 3 following follow VBG cord-006870-f5w6fw6q 6597 4 initiation initiation NN cord-006870-f5w6fw6q 6597 5 of of IN cord-006870-f5w6fw6q 6597 6 PJP PJP NNP cord-006870-f5w6fw6q 6597 7 treatment treatment NN cord-006870-f5w6fw6q 6597 8 with with IN cord-006870-f5w6fw6q 6597 9 Bactrim Bactrim NNP cord-006870-f5w6fw6q 6597 10 his -PRON- PRP$ cord-006870-f5w6fw6q 6597 11 chest chest NN cord-006870-f5w6fw6q 6597 12 x x NNS cord-006870-f5w6fw6q 6597 13 - - NNS cord-006870-f5w6fw6q 6597 14 rays ray NNS cord-006870-f5w6fw6q 6597 15 and and CC cord-006870-f5w6fw6q 6597 16 lung lung NN cord-006870-f5w6fw6q 6597 17 compliance compliance NN cord-006870-f5w6fw6q 6597 18 began begin VBD cord-006870-f5w6fw6q 6597 19 to to TO cord-006870-f5w6fw6q 6597 20 improve improve VB cord-006870-f5w6fw6q 6597 21 . . . cord-006870-f5w6fw6q 6598 1 He -PRON- PRP cord-006870-f5w6fw6q 6598 2 remained remain VBD cord-006870-f5w6fw6q 6598 3 on on IN cord-006870-f5w6fw6q 6598 4 ECMO ECMO NNP cord-006870-f5w6fw6q 6598 5 for for IN cord-006870-f5w6fw6q 6598 6 a a DT cord-006870-f5w6fw6q 6598 7 total total NN cord-006870-f5w6fw6q 6598 8 of of IN cord-006870-f5w6fw6q 6598 9 10 10 CD cord-006870-f5w6fw6q 6598 10 days day NNS cord-006870-f5w6fw6q 6598 11 before before IN cord-006870-f5w6fw6q 6598 12 decannulation decannulation NN cord-006870-f5w6fw6q 6598 13 . . . cord-006870-f5w6fw6q 6599 1 He -PRON- PRP cord-006870-f5w6fw6q 6599 2 underwent undergo VBD cord-006870-f5w6fw6q 6599 3 induction induction NN cord-006870-f5w6fw6q 6599 4 chemotherapy chemotherapy NN cord-006870-f5w6fw6q 6599 5 for for IN cord-006870-f5w6fw6q 6599 6 four four CD cord-006870-f5w6fw6q 6599 7 weeks week NNS cord-006870-f5w6fw6q 6599 8 for for IN cord-006870-f5w6fw6q 6599 9 meningitis meningitis NN cord-006870-f5w6fw6q 6599 10 . . . cord-006870-f5w6fw6q 6600 1 This this DT cord-006870-f5w6fw6q 6600 2 case case NN cord-006870-f5w6fw6q 6600 3 report report NN cord-006870-f5w6fw6q 6600 4 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 6600 5 the the DT cord-006870-f5w6fw6q 6600 6 use use NN cord-006870-f5w6fw6q 6600 7 of of IN cord-006870-f5w6fw6q 6600 8 ECMO ECMO NNP cord-006870-f5w6fw6q 6600 9 in in IN cord-006870-f5w6fw6q 6600 10 a a DT cord-006870-f5w6fw6q 6600 11 complicated complicated JJ cord-006870-f5w6fw6q 6600 12 and and CC cord-006870-f5w6fw6q 6600 13 critically critically RB cord-006870-f5w6fw6q 6600 14 ill ill JJ cord-006870-f5w6fw6q 6600 15 patient patient NN cord-006870-f5w6fw6q 6600 16 with with IN cord-006870-f5w6fw6q 6600 17 AIDs AIDs NNP cord-006870-f5w6fw6q 6600 18 , , , cord-006870-f5w6fw6q 6600 19 PJP PJP NNP cord-006870-f5w6fw6q 6600 20 , , , cord-006870-f5w6fw6q 6600 21 and and CC cord-006870-f5w6fw6q 6600 22 Cryptoccous Cryptoccous NNP cord-006870-f5w6fw6q 6600 23 gattii gattii NNP cord-006870-f5w6fw6q 6600 24 meningitis meningitis NN cord-006870-f5w6fw6q 6600 25 . . . cord-006870-f5w6fw6q 6601 1 To to IN cord-006870-f5w6fw6q 6601 2 our -PRON- PRP$ cord-006870-f5w6fw6q 6601 3 knowledge knowledge NN cord-006870-f5w6fw6q 6601 4 , , , cord-006870-f5w6fw6q 6601 5 few few JJ cord-006870-f5w6fw6q 6601 6 cases case NNS cord-006870-f5w6fw6q 6601 7 of of IN cord-006870-f5w6fw6q 6601 8 ARDS ARDS NNP cord-006870-f5w6fw6q 6601 9 secondary secondary JJ cord-006870-f5w6fw6q 6601 10 to to IN cord-006870-f5w6fw6q 6601 11 PJP PJP NNP cord-006870-f5w6fw6q 6601 12 are be VBP cord-006870-f5w6fw6q 6601 13 reported report VBN cord-006870-f5w6fw6q 6601 14 and and CC cord-006870-f5w6fw6q 6601 15 none none NN cord-006870-f5w6fw6q 6601 16 are be VBP cord-006870-f5w6fw6q 6601 17 reported report VBN cord-006870-f5w6fw6q 6601 18 with with IN cord-006870-f5w6fw6q 6601 19 concurrent concurrent JJ cord-006870-f5w6fw6q 6601 20 Cryptococcus Cryptococcus NNP cord-006870-f5w6fw6q 6601 21 gattii gattii NN cord-006870-f5w6fw6q 6601 22 infection infection NN cord-006870-f5w6fw6q 6601 23 . . . cord-006870-f5w6fw6q 6602 1 Sympathetic sympathetic JJ cord-006870-f5w6fw6q 6602 2 storming storming NN cord-006870-f5w6fw6q 6602 3 occurs occur VBZ cord-006870-f5w6fw6q 6602 4 during during IN cord-006870-f5w6fw6q 6602 5 the the DT cord-006870-f5w6fw6q 6602 6 acute acute JJ cord-006870-f5w6fw6q 6602 7 care care NN cord-006870-f5w6fw6q 6602 8 of of IN cord-006870-f5w6fw6q 6602 9 patients patient NNS cord-006870-f5w6fw6q 6602 10 following follow VBG cord-006870-f5w6fw6q 6602 11 severe severe JJ cord-006870-f5w6fw6q 6602 12 brain brain NN cord-006870-f5w6fw6q 6602 13 injury injury NN cord-006870-f5w6fw6q 6602 14 . . . cord-006870-f5w6fw6q 6603 1 Cannabinoid cannabinoid NN cord-006870-f5w6fw6q 6603 2 CB1 CB1 NNP cord-006870-f5w6fw6q 6603 3 receptors receptor NNS cord-006870-f5w6fw6q 6603 4 ( ( -LRB- cord-006870-f5w6fw6q 6603 5 CB1R CB1R NNP cord-006870-f5w6fw6q 6603 6 ) ) -RRB- cord-006870-f5w6fw6q 6603 7 mediate mediate VB cord-006870-f5w6fw6q 6603 8 the the DT cord-006870-f5w6fw6q 6603 9 effects effect NNS cord-006870-f5w6fw6q 6603 10 of of IN cord-006870-f5w6fw6q 6603 11 delta(9)-tetrahydrocannabinol delta(9)-tetrahydrocannabinol NN cord-006870-f5w6fw6q 6603 12 ( ( -LRB- cord-006870-f5w6fw6q 6603 13 THC THC NNP cord-006870-f5w6fw6q 6603 14 ) ) -RRB- cord-006870-f5w6fw6q 6603 15 , , , cord-006870-f5w6fw6q 6603 16 the the DT cord-006870-f5w6fw6q 6603 17 psychoactive psychoactive JJ cord-006870-f5w6fw6q 6603 18 component component NN cord-006870-f5w6fw6q 6603 19 in in IN cord-006870-f5w6fw6q 6603 20 marijuana marijuana NN cord-006870-f5w6fw6q 6603 21 . . . cord-006870-f5w6fw6q 6604 1 Expression expression NN cord-006870-f5w6fw6q 6604 2 of of IN cord-006870-f5w6fw6q 6604 3 CB1R CB1R NNP cord-006870-f5w6fw6q 6604 4 is be VBZ cord-006870-f5w6fw6q 6604 5 widespread widespread JJ cord-006870-f5w6fw6q 6604 6 in in IN cord-006870-f5w6fw6q 6604 7 the the DT cord-006870-f5w6fw6q 6604 8 central central JJ cord-006870-f5w6fw6q 6604 9 nervous nervous JJ cord-006870-f5w6fw6q 6604 10 system system NN cord-006870-f5w6fw6q 6604 11 and and CC cord-006870-f5w6fw6q 6604 12 includes include VBZ cord-006870-f5w6fw6q 6604 13 the the DT cord-006870-f5w6fw6q 6604 14 hypothalamus hypothalamus NN cord-006870-f5w6fw6q 6604 15 , , , cord-006870-f5w6fw6q 6604 16 which which WDT cord-006870-f5w6fw6q 6604 17 is be VBZ cord-006870-f5w6fw6q 6604 18 thought think VBN cord-006870-f5w6fw6q 6604 19 to to TO cord-006870-f5w6fw6q 6604 20 mediate mediate VB cord-006870-f5w6fw6q 6604 21 the the DT cord-006870-f5w6fw6q 6604 22 hypothermic hypothermic JJ cord-006870-f5w6fw6q 6604 23 inducing inducing JJ cord-006870-f5w6fw6q 6604 24 effects effect NNS cord-006870-f5w6fw6q 6604 25 of of IN cord-006870-f5w6fw6q 6604 26 cannabinoids cannabinoid NNS cord-006870-f5w6fw6q 6604 27 . . . cord-006870-f5w6fw6q 6605 1 Dronabinol dronabinol NN cord-006870-f5w6fw6q 6605 2 is be VBZ cord-006870-f5w6fw6q 6605 3 a a DT cord-006870-f5w6fw6q 6605 4 synthetic synthetic JJ cord-006870-f5w6fw6q 6605 5 analogue analogue NN cord-006870-f5w6fw6q 6605 6 of of IN cord-006870-f5w6fw6q 6606 1 THC thc NN cord-006870-f5w6fw6q 6606 2 We -PRON- PRP cord-006870-f5w6fw6q 6606 3 present present VBP cord-006870-f5w6fw6q 6606 4 a a DT cord-006870-f5w6fw6q 6606 5 novel novel JJ cord-006870-f5w6fw6q 6606 6 therapeutic therapeutic JJ cord-006870-f5w6fw6q 6606 7 use use NN cord-006870-f5w6fw6q 6606 8 of of IN cord-006870-f5w6fw6q 6606 9 cannabinoids cannabinoid NNS cord-006870-f5w6fw6q 6606 10 in in IN cord-006870-f5w6fw6q 6606 11 a a DT cord-006870-f5w6fw6q 6606 12 case case NN cord-006870-f5w6fw6q 6606 13 of of IN cord-006870-f5w6fw6q 6606 14 super super JJ cord-006870-f5w6fw6q 6606 15 - - JJ cord-006870-f5w6fw6q 6606 16 refractory refractory JJ cord-006870-f5w6fw6q 6606 17 sympathetic sympathetic JJ cord-006870-f5w6fw6q 6606 18 storming storm VBG cord-006870-f5w6fw6q 6606 19 following follow VBG cord-006870-f5w6fw6q 6606 20 coccidioidal coccidioidal JJ cord-006870-f5w6fw6q 6606 21 meningitis meningitis NN cord-006870-f5w6fw6q 6606 22 and and CC cord-006870-f5w6fw6q 6606 23 extensive extensive JJ cord-006870-f5w6fw6q 6606 24 bilateral bilateral JJ cord-006870-f5w6fw6q 6606 25 subcortical subcortical JJ cord-006870-f5w6fw6q 6606 26 stroke stroke NN cord-006870-f5w6fw6q 6607 1 A a DT cord-006870-f5w6fw6q 6607 2 26-year 26-year JJ cord-006870-f5w6fw6q 6607 3 - - HYPH cord-006870-f5w6fw6q 6607 4 old old JJ cord-006870-f5w6fw6q 6607 5 previously previously RB cord-006870-f5w6fw6q 6607 6 healthy healthy JJ cord-006870-f5w6fw6q 6607 7 man man NN cord-006870-f5w6fw6q 6607 8 was be VBD cord-006870-f5w6fw6q 6607 9 transferred transfer VBN cord-006870-f5w6fw6q 6607 10 from from IN cord-006870-f5w6fw6q 6607 11 an an DT cord-006870-f5w6fw6q 6607 12 outside outside JJ cord-006870-f5w6fw6q 6607 13 hospital hospital NN cord-006870-f5w6fw6q 6607 14 for for IN cord-006870-f5w6fw6q 6607 15 treatment treatment NN cord-006870-f5w6fw6q 6607 16 of of IN cord-006870-f5w6fw6q 6607 17 meningitis meningitis NN cord-006870-f5w6fw6q 6607 18 , , , cord-006870-f5w6fw6q 6607 19 vasculitis vasculitis NN cord-006870-f5w6fw6q 6607 20 , , , cord-006870-f5w6fw6q 6607 21 and and CC cord-006870-f5w6fw6q 6607 22 hydrocephalus hydrocephalus NN cord-006870-f5w6fw6q 6607 23 requiring require VBG cord-006870-f5w6fw6q 6607 24 placement placement NN cord-006870-f5w6fw6q 6607 25 of of IN cord-006870-f5w6fw6q 6607 26 a a DT cord-006870-f5w6fw6q 6607 27 ventriculostomy ventriculostomy NN cord-006870-f5w6fw6q 6607 28 . . . cord-006870-f5w6fw6q 6608 1 Workup Workup NNP cord-006870-f5w6fw6q 6608 2 subsequently subsequently RB cord-006870-f5w6fw6q 6608 3 revealed reveal VBD cord-006870-f5w6fw6q 6608 4 coccidioidal coccidioidal JJ cord-006870-f5w6fw6q 6608 5 meningitis meningitis NN cord-006870-f5w6fw6q 6608 6 . . . cord-006870-f5w6fw6q 6609 1 During during IN cord-006870-f5w6fw6q 6609 2 hospitalization hospitalization NN cord-006870-f5w6fw6q 6609 3 the the DT cord-006870-f5w6fw6q 6609 4 patient patient NN cord-006870-f5w6fw6q 6609 5 had have VBD cord-006870-f5w6fw6q 6609 6 severe severe JJ cord-006870-f5w6fw6q 6609 7 vasospasm vasospasm NN cord-006870-f5w6fw6q 6609 8 , , , cord-006870-f5w6fw6q 6609 9 elevated elevated JJ cord-006870-f5w6fw6q 6609 10 intracranial intracranial JJ cord-006870-f5w6fw6q 6609 11 pressure pressure NN cord-006870-f5w6fw6q 6609 12 , , , cord-006870-f5w6fw6q 6609 13 diabetes diabetes NN cord-006870-f5w6fw6q 6609 14 insipidus insipidus NN cord-006870-f5w6fw6q 6609 15 , , , cord-006870-f5w6fw6q 6609 16 cerebral cerebral JJ cord-006870-f5w6fw6q 6609 17 salt salt NN cord-006870-f5w6fw6q 6609 18 wasting wasting NN cord-006870-f5w6fw6q 6609 19 , , , cord-006870-f5w6fw6q 6609 20 and and CC cord-006870-f5w6fw6q 6609 21 severe severe JJ cord-006870-f5w6fw6q 6609 22 sympathetic sympathetic JJ cord-006870-f5w6fw6q 6609 23 storming storming NN cord-006870-f5w6fw6q 6609 24 . . . cord-006870-f5w6fw6q 6610 1 Intermittent intermittent JJ cord-006870-f5w6fw6q 6610 2 storming storm VBG cord-006870-f5w6fw6q 6610 3 episodes episode NNS cord-006870-f5w6fw6q 6610 4 with with IN cord-006870-f5w6fw6q 6610 5 high high JJ cord-006870-f5w6fw6q 6610 6 fever fever NN cord-006870-f5w6fw6q 6610 7 persisted persist VBD cord-006870-f5w6fw6q 6610 8 for for IN cord-006870-f5w6fw6q 6610 9 over over IN cord-006870-f5w6fw6q 6610 10 8 8 CD cord-006870-f5w6fw6q 6610 11 weeks week NNS cord-006870-f5w6fw6q 6610 12 despite despite IN cord-006870-f5w6fw6q 6610 13 treatment treatment NN cord-006870-f5w6fw6q 6610 14 with with IN cord-006870-f5w6fw6q 6610 15 bromocriptine bromocriptine NN cord-006870-f5w6fw6q 6610 16 , , , cord-006870-f5w6fw6q 6610 17 dantrolene dantrolene NNP cord-006870-f5w6fw6q 6610 18 , , , cord-006870-f5w6fw6q 6610 19 tylenol tylenol NNP cord-006870-f5w6fw6q 6610 20 , , , cord-006870-f5w6fw6q 6610 21 ibuprofen ibuprofen NN cord-006870-f5w6fw6q 6610 22 , , , cord-006870-f5w6fw6q 6610 23 phenobarbital phenobarbital NN cord-006870-f5w6fw6q 6610 24 , , , cord-006870-f5w6fw6q 6610 25 and and CC cord-006870-f5w6fw6q 6610 26 sinemet sinemet NNP cord-006870-f5w6fw6q 6610 27 . . . cord-006870-f5w6fw6q 6611 1 Due due IN cord-006870-f5w6fw6q 6611 2 to to IN cord-006870-f5w6fw6q 6611 3 its -PRON- PRP$ cord-006870-f5w6fw6q 6611 4 mechanism mechanism NN cord-006870-f5w6fw6q 6611 5 of of IN cord-006870-f5w6fw6q 6611 6 action action NN cord-006870-f5w6fw6q 6611 7 , , , cord-006870-f5w6fw6q 6611 8 a a DT cord-006870-f5w6fw6q 6611 9 trial trial NN cord-006870-f5w6fw6q 6611 10 of of IN cord-006870-f5w6fw6q 6611 11 dronabinol dronabinol NN cord-006870-f5w6fw6q 6611 12 10 10 CD cord-006870-f5w6fw6q 6611 13 mg mg NNP cord-006870-f5w6fw6q 6611 14 divided divide VBD cord-006870-f5w6fw6q 6611 15 twice twice RB cord-006870-f5w6fw6q 6611 16 daily daily RB cord-006870-f5w6fw6q 6611 17 was be VBD cord-006870-f5w6fw6q 6611 18 tried try VBN cord-006870-f5w6fw6q 6611 19 . . . cord-006870-f5w6fw6q 6612 1 The the DT cord-006870-f5w6fw6q 6612 2 storming storm VBG cord-006870-f5w6fw6q 6612 3 episodes episode NNS cord-006870-f5w6fw6q 6612 4 ceased cease VBD cord-006870-f5w6fw6q 6612 5 and and CC cord-006870-f5w6fw6q 6612 6 within within IN cord-006870-f5w6fw6q 6612 7 6 6 CD cord-006870-f5w6fw6q 6612 8 hours hour NNS cord-006870-f5w6fw6q 6612 9 the the DT cord-006870-f5w6fw6q 6612 10 average average JJ cord-006870-f5w6fw6q 6612 11 temperature temperature NN cord-006870-f5w6fw6q 6612 12 decreased decrease VBD cord-006870-f5w6fw6q 6612 13 by by IN cord-006870-f5w6fw6q 6612 14 about about RB cord-006870-f5w6fw6q 6612 15 2.5 2.5 CD cord-006870-f5w6fw6q 6612 16 degree degree NN cord-006870-f5w6fw6q 6612 17 centigrade centigrade JJ cord-006870-f5w6fw6q 6612 18 . . . cord-006870-f5w6fw6q 6613 1 Temperature temperature NN cord-006870-f5w6fw6q 6613 2 over over IN cord-006870-f5w6fw6q 6613 3 the the DT cord-006870-f5w6fw6q 6613 4 next next JJ cord-006870-f5w6fw6q 6613 5 several several JJ cord-006870-f5w6fw6q 6613 6 days day NNS cord-006870-f5w6fw6q 6613 7 was be VBD cord-006870-f5w6fw6q 6613 8 better well RBR cord-006870-f5w6fw6q 6613 9 controlled control VBN cord-006870-f5w6fw6q 6613 10 with with IN cord-006870-f5w6fw6q 6613 11 a a DT cord-006870-f5w6fw6q 6613 12 substantial substantial JJ cord-006870-f5w6fw6q 6613 13 reduction reduction NN cord-006870-f5w6fw6q 6613 14 in in IN cord-006870-f5w6fw6q 6613 15 use use NN cord-006870-f5w6fw6q 6613 16 of of IN cord-006870-f5w6fw6q 6613 17 anti anti JJ cord-006870-f5w6fw6q 6613 18 - - JJ cord-006870-f5w6fw6q 6613 19 pyretics pyretic NNS cord-006870-f5w6fw6q 6613 20 , , , cord-006870-f5w6fw6q 6613 21 surface surface NN cord-006870-f5w6fw6q 6613 22 cooling cooling NN cord-006870-f5w6fw6q 6613 23 measures measure NNS cord-006870-f5w6fw6q 6613 24 , , , cord-006870-f5w6fw6q 6613 25 and and CC cord-006870-f5w6fw6q 6613 26 other other JJ cord-006870-f5w6fw6q 6613 27 storming storm VBG cord-006870-f5w6fw6q 6613 28 medications medication NNS cord-006870-f5w6fw6q 6614 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6614 2 case case NN cord-006870-f5w6fw6q 6614 3 highlights highlight VBZ cord-006870-f5w6fw6q 6614 4 a a DT cord-006870-f5w6fw6q 6614 5 novel novel JJ cord-006870-f5w6fw6q 6614 6 therapeutic therapeutic JJ cord-006870-f5w6fw6q 6614 7 use use NN cord-006870-f5w6fw6q 6614 8 of of IN cord-006870-f5w6fw6q 6614 9 cannabinoids cannabinoid NNS cord-006870-f5w6fw6q 6614 10 in in IN cord-006870-f5w6fw6q 6614 11 super super JJ cord-006870-f5w6fw6q 6614 12 - - JJ cord-006870-f5w6fw6q 6614 13 refractory refractory JJ cord-006870-f5w6fw6q 6614 14 sympathetic sympathetic JJ cord-006870-f5w6fw6q 6614 15 storming storming NN cord-006870-f5w6fw6q 6614 16 related relate VBN cord-006870-f5w6fw6q 6614 17 to to IN cord-006870-f5w6fw6q 6614 18 brain brain NN cord-006870-f5w6fw6q 6614 19 injury injury NN cord-006870-f5w6fw6q 6614 20 . . . cord-006870-f5w6fw6q 6615 1 Dronabinol Dronabinol NNP cord-006870-f5w6fw6q 6615 2 may may MD cord-006870-f5w6fw6q 6615 3 be be VB cord-006870-f5w6fw6q 6615 4 an an DT cord-006870-f5w6fw6q 6615 5 alternative alternative JJ cord-006870-f5w6fw6q 6615 6 pharmacotherapy pharmacotherapy NN cord-006870-f5w6fw6q 6615 7 with with IN cord-006870-f5w6fw6q 6615 8 unique unique JJ cord-006870-f5w6fw6q 6615 9 mechanism mechanism NN cord-006870-f5w6fw6q 6615 10 of of IN cord-006870-f5w6fw6q 6615 11 action action NN cord-006870-f5w6fw6q 6615 12 in in IN cord-006870-f5w6fw6q 6615 13 difficult difficult JJ cord-006870-f5w6fw6q 6615 14 to to TO cord-006870-f5w6fw6q 6615 15 control control VB cord-006870-f5w6fw6q 6615 16 sympathetic sympathetic JJ cord-006870-f5w6fw6q 6615 17 storming storm VBG cord-006870-f5w6fw6q 6615 18 Patients patient NNS cord-006870-f5w6fw6q 6615 19 with with IN cord-006870-f5w6fw6q 6615 20 poor poor JJ cord-006870-f5w6fw6q 6615 21 grade grade NN cord-006870-f5w6fw6q 6615 22 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6615 23 hemorrhage(SAH hemorrhage(sah JJ cord-006870-f5w6fw6q 6615 24 ) ) -RRB- cord-006870-f5w6fw6q 6615 25 commonly commonly RB cord-006870-f5w6fw6q 6615 26 present present JJ cord-006870-f5w6fw6q 6615 27 with with IN cord-006870-f5w6fw6q 6615 28 significant significant JJ cord-006870-f5w6fw6q 6615 29 mental mental JJ cord-006870-f5w6fw6q 6615 30 status status NN cord-006870-f5w6fw6q 6615 31 changes change NNS cord-006870-f5w6fw6q 6615 32 that that WDT cord-006870-f5w6fw6q 6615 33 preclude preclude VBP cord-006870-f5w6fw6q 6615 34 reliance reliance NN cord-006870-f5w6fw6q 6615 35 on on IN cord-006870-f5w6fw6q 6615 36 neurologic neurologic JJ cord-006870-f5w6fw6q 6615 37 exam exam NN cord-006870-f5w6fw6q 6615 38 for for IN cord-006870-f5w6fw6q 6615 39 screening screening NN cord-006870-f5w6fw6q 6615 40 for for IN cord-006870-f5w6fw6q 6615 41 neurologic neurologic JJ cord-006870-f5w6fw6q 6615 42 deterioration deterioration NN cord-006870-f5w6fw6q 6615 43 . . . cord-006870-f5w6fw6q 6616 1 Jugular jugular NN cord-006870-f5w6fw6q 6616 2 venous venous JJ cord-006870-f5w6fw6q 6616 3 oximetry oximetry NN cord-006870-f5w6fw6q 6616 4 monitoring monitoring NN cord-006870-f5w6fw6q 6616 5 has have VBZ cord-006870-f5w6fw6q 6616 6 been be VBN cord-006870-f5w6fw6q 6616 7 suggested suggest VBN cord-006870-f5w6fw6q 6616 8 for for IN cord-006870-f5w6fw6q 6616 9 use use NN cord-006870-f5w6fw6q 6616 10 in in IN cord-006870-f5w6fw6q 6616 11 guidance guidance NN cord-006870-f5w6fw6q 6616 12 of of IN cord-006870-f5w6fw6q 6616 13 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 6616 14 therapy therapy NN cord-006870-f5w6fw6q 6616 15 , , , cord-006870-f5w6fw6q 6616 16 barbiturate barbiturate NN cord-006870-f5w6fw6q 6616 17 coma coma NN cord-006870-f5w6fw6q 6616 18 , , , cord-006870-f5w6fw6q 6616 19 and and CC cord-006870-f5w6fw6q 6616 20 vasospasm vasospasm NN cord-006870-f5w6fw6q 6616 21 monitoring monitoring NN cord-006870-f5w6fw6q 6616 22 . . . cord-006870-f5w6fw6q 6617 1 No no DT cord-006870-f5w6fw6q 6617 2 studies study NNS cord-006870-f5w6fw6q 6617 3 are be VBP cord-006870-f5w6fw6q 6617 4 found find VBN cord-006870-f5w6fw6q 6617 5 in in IN cord-006870-f5w6fw6q 6617 6 literature literature NN cord-006870-f5w6fw6q 6617 7 validating validate VBG cord-006870-f5w6fw6q 6617 8 its -PRON- PRP$ cord-006870-f5w6fw6q 6617 9 use use NN cord-006870-f5w6fw6q 6617 10 in in IN cord-006870-f5w6fw6q 6617 11 SAH SAH NNP cord-006870-f5w6fw6q 6617 12 . . . cord-006870-f5w6fw6q 6618 1 Milrinone Milrinone NNP cord-006870-f5w6fw6q 6618 2 has have VBZ cord-006870-f5w6fw6q 6618 3 been be VBN cord-006870-f5w6fw6q 6618 4 using use VBG cord-006870-f5w6fw6q 6618 5 for for IN cord-006870-f5w6fw6q 6618 6 the the DT cord-006870-f5w6fw6q 6618 7 treatment treatment NN cord-006870-f5w6fw6q 6618 8 of of IN cord-006870-f5w6fw6q 6618 9 vasospasm vasospasm NN cord-006870-f5w6fw6q 6618 10 in in IN cord-006870-f5w6fw6q 6618 11 SAH SAH NNP cord-006870-f5w6fw6q 6618 12 in in IN cord-006870-f5w6fw6q 6618 13 an an DT cord-006870-f5w6fw6q 6618 14 established establish VBN cord-006870-f5w6fw6q 6618 15 protocol protocol NN cord-006870-f5w6fw6q 6618 16 in in IN cord-006870-f5w6fw6q 6618 17 The the DT cord-006870-f5w6fw6q 6618 18 Montreal Montreal NNP cord-006870-f5w6fw6q 6618 19 Neurological Neurological NNP cord-006870-f5w6fw6q 6618 20 Hospital Hospital NNP cord-006870-f5w6fw6q 6618 21 . . . cord-006870-f5w6fw6q 6619 1 This this DT cord-006870-f5w6fw6q 6619 2 study study NN cord-006870-f5w6fw6q 6619 3 was be VBD cord-006870-f5w6fw6q 6619 4 performed perform VBN cord-006870-f5w6fw6q 6619 5 using use VBG cord-006870-f5w6fw6q 6619 6 multiple multiple JJ cord-006870-f5w6fw6q 6619 7 methods method NNS cord-006870-f5w6fw6q 6619 8 of of IN cord-006870-f5w6fw6q 6619 9 monitoring monitoring NN cord-006870-f5w6fw6q 6619 10 , , , cord-006870-f5w6fw6q 6619 11 but but CC cord-006870-f5w6fw6q 6619 12 not not RB cord-006870-f5w6fw6q 6619 13 jugular jugular NN cord-006870-f5w6fw6q 6619 14 bulb bulb NN cord-006870-f5w6fw6q 6619 15 oximetry oximetry NN cord-006870-f5w6fw6q 6619 16 . . . cord-006870-f5w6fw6q 6620 1 We -PRON- PRP cord-006870-f5w6fw6q 6620 2 report report VBP cord-006870-f5w6fw6q 6620 3 one one CD cord-006870-f5w6fw6q 6620 4 case case NN cord-006870-f5w6fw6q 6620 5 with with IN cord-006870-f5w6fw6q 6620 6 high high JJ cord-006870-f5w6fw6q 6620 7 grade grade NN cord-006870-f5w6fw6q 6620 8 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6620 9 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6620 10 complicated complicate VBN cord-006870-f5w6fw6q 6620 11 by by IN cord-006870-f5w6fw6q 6620 12 vasospasm vasospasm NN cord-006870-f5w6fw6q 6620 13 treated treat VBN cord-006870-f5w6fw6q 6620 14 with with IN cord-006870-f5w6fw6q 6620 15 milrinone milrinone NN cord-006870-f5w6fw6q 6620 16 using use VBG cord-006870-f5w6fw6q 6620 17 jugular jugular NN cord-006870-f5w6fw6q 6620 18 bulb bulb NN cord-006870-f5w6fw6q 6620 19 monitoring monitoring NN cord-006870-f5w6fw6q 6620 20 for for IN cord-006870-f5w6fw6q 6620 21 dose dose JJ cord-006870-f5w6fw6q 6620 22 titration titration NN cord-006870-f5w6fw6q 6620 23 . . . cord-006870-f5w6fw6q 6621 1 Methods method NNS cord-006870-f5w6fw6q 6621 2 71 71 CD cord-006870-f5w6fw6q 6621 3 years year NNS cord-006870-f5w6fw6q 6621 4 old old JJ cord-006870-f5w6fw6q 6621 5 female female NN cord-006870-f5w6fw6q 6621 6 presented present VBN cord-006870-f5w6fw6q 6621 7 with with IN cord-006870-f5w6fw6q 6621 8 thunderclap thunderclap NN cord-006870-f5w6fw6q 6621 9 headache headache NN cord-006870-f5w6fw6q 6621 10 and and CC cord-006870-f5w6fw6q 6621 11 subsequently subsequently RB cord-006870-f5w6fw6q 6621 12 became become VBD cord-006870-f5w6fw6q 6621 13 comatose comatose JJ cord-006870-f5w6fw6q 6621 14 . . . cord-006870-f5w6fw6q 6622 1 Noncontrast Noncontrast NNP cord-006870-f5w6fw6q 6622 2 head head NN cord-006870-f5w6fw6q 6622 3 computer computer NN cord-006870-f5w6fw6q 6622 4 tomography tomography NN cord-006870-f5w6fw6q 6622 5 showed show VBD cord-006870-f5w6fw6q 6622 6 posterior posterior JJ cord-006870-f5w6fw6q 6622 7 fossa fossa NN cord-006870-f5w6fw6q 6622 8 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6622 9 blood blood NN cord-006870-f5w6fw6q 6622 10 . . . cord-006870-f5w6fw6q 6623 1 She -PRON- PRP cord-006870-f5w6fw6q 6623 2 was be VBD cord-006870-f5w6fw6q 6623 3 intubated intubate VBN cord-006870-f5w6fw6q 6623 4 , , , cord-006870-f5w6fw6q 6623 5 external external JJ cord-006870-f5w6fw6q 6623 6 ventricular ventricular JJ cord-006870-f5w6fw6q 6623 7 drain drain NN cord-006870-f5w6fw6q 6623 8 ( ( -LRB- cord-006870-f5w6fw6q 6623 9 EVD EVD NNP cord-006870-f5w6fw6q 6623 10 ) ) -RRB- cord-006870-f5w6fw6q 6623 11 was be VBD cord-006870-f5w6fw6q 6623 12 placed place VBN cord-006870-f5w6fw6q 6623 13 and and CC cord-006870-f5w6fw6q 6623 14 she -PRON- PRP cord-006870-f5w6fw6q 6623 15 was be VBD cord-006870-f5w6fw6q 6623 16 admitted admit VBN cord-006870-f5w6fw6q 6623 17 to to IN cord-006870-f5w6fw6q 6623 18 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 6623 19 intensive intensive JJ cord-006870-f5w6fw6q 6623 20 care care NN cord-006870-f5w6fw6q 6623 21 unit unit NN cord-006870-f5w6fw6q 6623 22 ( ( -LRB- cord-006870-f5w6fw6q 6623 23 NSICU NSICU NNP cord-006870-f5w6fw6q 6623 24 ) ) -RRB- cord-006870-f5w6fw6q 6623 25 . . . cord-006870-f5w6fw6q 6624 1 Angiogram Angiogram NNP cord-006870-f5w6fw6q 6624 2 showed show VBD cord-006870-f5w6fw6q 6624 3 left leave VBN cord-006870-f5w6fw6q 6624 4 posterior posterior JJ cord-006870-f5w6fw6q 6624 5 inferior inferior JJ cord-006870-f5w6fw6q 6624 6 cerebellar cerebellar JJ cord-006870-f5w6fw6q 6624 7 artery artery NN cord-006870-f5w6fw6q 6624 8 aneurysm aneurysm NN cord-006870-f5w6fw6q 6624 9 and and CC cord-006870-f5w6fw6q 6624 10 was be VBD cord-006870-f5w6fw6q 6624 11 successfully successfully RB cord-006870-f5w6fw6q 6624 12 coiled coil VBN cord-006870-f5w6fw6q 6624 13 . . . cord-006870-f5w6fw6q 6625 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6625 2 hospital hospital NN cord-006870-f5w6fw6q 6625 3 course course NN cord-006870-f5w6fw6q 6625 4 was be VBD cord-006870-f5w6fw6q 6625 5 complicated complicate VBN cord-006870-f5w6fw6q 6625 6 by by IN cord-006870-f5w6fw6q 6625 7 refractory refractory JJ cord-006870-f5w6fw6q 6625 8 symptomatic symptomatic JJ cord-006870-f5w6fw6q 6625 9 vasospasm vasospasm NN cord-006870-f5w6fw6q 6625 10 . . . cord-006870-f5w6fw6q 6626 1 Angiogram Angiogram NNP cord-006870-f5w6fw6q 6626 2 showed show VBD cord-006870-f5w6fw6q 6626 3 basilar basilar JJ cord-006870-f5w6fw6q 6626 4 artery artery NN cord-006870-f5w6fw6q 6626 5 vasospasm vasospasm NN cord-006870-f5w6fw6q 6626 6 treated treat VBN cord-006870-f5w6fw6q 6626 7 with with IN cord-006870-f5w6fw6q 6626 8 intra intra JJ cord-006870-f5w6fw6q 6626 9 - - JJ cord-006870-f5w6fw6q 6626 10 arterial arterial JJ cord-006870-f5w6fw6q 6626 11 verapamil verapamil NN cord-006870-f5w6fw6q 6626 12 . . . cord-006870-f5w6fw6q 6627 1 Post post JJ cord-006870-f5w6fw6q 6627 2 procedure procedure NN cord-006870-f5w6fw6q 6627 3 patient patient NN cord-006870-f5w6fw6q 6627 4 was be VBD cord-006870-f5w6fw6q 6627 5 not not RB cord-006870-f5w6fw6q 6627 6 able able JJ cord-006870-f5w6fw6q 6627 7 to to TO cord-006870-f5w6fw6q 6627 8 tolerate tolerate VB cord-006870-f5w6fw6q 6627 9 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 6627 10 due due IN cord-006870-f5w6fw6q 6627 11 to to IN cord-006870-f5w6fw6q 6627 12 tachycardia tachycardia NN cord-006870-f5w6fw6q 6627 13 and and CC cord-006870-f5w6fw6q 6627 14 could could MD cord-006870-f5w6fw6q 6627 15 not not RB cord-006870-f5w6fw6q 6627 16 maintain maintain VB cord-006870-f5w6fw6q 6627 17 hypertension hypertension NN cord-006870-f5w6fw6q 6627 18 on on IN cord-006870-f5w6fw6q 6627 19 phenylephrine phenylephrine NN cord-006870-f5w6fw6q 6627 20 . . . cord-006870-f5w6fw6q 6628 1 Milrinone Milrinone NNP cord-006870-f5w6fw6q 6628 2 was be VBD cord-006870-f5w6fw6q 6628 3 then then RB cord-006870-f5w6fw6q 6628 4 started start VBN cord-006870-f5w6fw6q 6628 5 . . . cord-006870-f5w6fw6q 6629 1 Jugular jugular NN cord-006870-f5w6fw6q 6629 2 bulb bulb NN cord-006870-f5w6fw6q 6629 3 catheter catheter NN cord-006870-f5w6fw6q 6629 4 was be VBD cord-006870-f5w6fw6q 6629 5 place place NN cord-006870-f5w6fw6q 6629 6 because because IN cord-006870-f5w6fw6q 6629 7 the the DT cord-006870-f5w6fw6q 6629 8 area area NN cord-006870-f5w6fw6q 6629 9 at at IN cord-006870-f5w6fw6q 6629 10 risk risk NN cord-006870-f5w6fw6q 6629 11 was be VBD cord-006870-f5w6fw6q 6629 12 not not RB cord-006870-f5w6fw6q 6629 13 amenable amenable JJ cord-006870-f5w6fw6q 6629 14 to to IN cord-006870-f5w6fw6q 6629 15 invasive invasive JJ cord-006870-f5w6fw6q 6629 16 multimodality multimodality NN cord-006870-f5w6fw6q 6629 17 monitoring monitoring NN cord-006870-f5w6fw6q 6629 18 . . . cord-006870-f5w6fw6q 6630 1 Oximetry Oximetry NNP cord-006870-f5w6fw6q 6630 2 was be VBD cord-006870-f5w6fw6q 6630 3 monitored monitor VBN cord-006870-f5w6fw6q 6630 4 and and CC cord-006870-f5w6fw6q 6630 5 her -PRON- PRP$ cord-006870-f5w6fw6q 6630 6 milrinone milrinone JJ cord-006870-f5w6fw6q 6630 7 rate rate NN cord-006870-f5w6fw6q 6630 8 was be VBD cord-006870-f5w6fw6q 6630 9 titrated titrate VBN cord-006870-f5w6fw6q 6630 10 to to IN cord-006870-f5w6fw6q 6630 11 goal goal NN cord-006870-f5w6fw6q 6630 12 of of IN cord-006870-f5w6fw6q 6630 13 venous venous JJ cord-006870-f5w6fw6q 6630 14 oximetry oximetry NN cord-006870-f5w6fw6q 6630 15 in in IN cord-006870-f5w6fw6q 6630 16 the the DT cord-006870-f5w6fw6q 6630 17 range range NN cord-006870-f5w6fw6q 6630 18 of of IN cord-006870-f5w6fw6q 6630 19 50 50 CD cord-006870-f5w6fw6q 6630 20 - - SYM cord-006870-f5w6fw6q 6630 21 70 70 CD cord-006870-f5w6fw6q 6630 22 % % NN cord-006870-f5w6fw6q 6630 23 . . . cord-006870-f5w6fw6q 6631 1 On on IN cord-006870-f5w6fw6q 6631 2 day day NN cord-006870-f5w6fw6q 6631 3 20 20 CD cord-006870-f5w6fw6q 6631 4 , , , cord-006870-f5w6fw6q 6631 5 angiogram angiogram NN cord-006870-f5w6fw6q 6631 6 showed show VBD cord-006870-f5w6fw6q 6631 7 no no DT cord-006870-f5w6fw6q 6631 8 more more JJR cord-006870-f5w6fw6q 6631 9 evidence evidence NN cord-006870-f5w6fw6q 6631 10 of of IN cord-006870-f5w6fw6q 6631 11 vasospasm vasospasm NN cord-006870-f5w6fw6q 6631 12 . . . cord-006870-f5w6fw6q 6632 1 Her -PRON- PRP$ cord-006870-f5w6fw6q 6632 2 exam exam NN cord-006870-f5w6fw6q 6632 3 was be VBD cord-006870-f5w6fw6q 6632 4 back back RB cord-006870-f5w6fw6q 6632 5 to to IN cord-006870-f5w6fw6q 6632 6 her -PRON- PRP cord-006870-f5w6fw6q 6632 7 prior prior JJ cord-006870-f5w6fw6q 6632 8 poor poor JJ cord-006870-f5w6fw6q 6632 9 baseline baseline NN cord-006870-f5w6fw6q 6632 10 . . . cord-006870-f5w6fw6q 6633 1 Subsequently subsequently RB cord-006870-f5w6fw6q 6633 2 , , , cord-006870-f5w6fw6q 6633 3 she -PRON- PRP cord-006870-f5w6fw6q 6633 4 was be VBD cord-006870-f5w6fw6q 6633 5 discharged discharge VBN cord-006870-f5w6fw6q 6633 6 to to IN cord-006870-f5w6fw6q 6633 7 long long JJ cord-006870-f5w6fw6q 6633 8 term term NN cord-006870-f5w6fw6q 6633 9 care care NN cord-006870-f5w6fw6q 6633 10 facility facility NN cord-006870-f5w6fw6q 6633 11 . . . cord-006870-f5w6fw6q 6634 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6634 2 case case NN cord-006870-f5w6fw6q 6634 3 demonstrates demonstrate VBZ cord-006870-f5w6fw6q 6634 4 the the DT cord-006870-f5w6fw6q 6634 5 benefit benefit NN cord-006870-f5w6fw6q 6634 6 of of IN cord-006870-f5w6fw6q 6634 7 using use VBG cord-006870-f5w6fw6q 6634 8 jugular jugular NN cord-006870-f5w6fw6q 6634 9 venous venous JJ cord-006870-f5w6fw6q 6634 10 oximetry oximetry NN cord-006870-f5w6fw6q 6634 11 monitoring monitoring NN cord-006870-f5w6fw6q 6634 12 guidance guidance NN cord-006870-f5w6fw6q 6634 13 for for IN cord-006870-f5w6fw6q 6634 14 milrinone milrinone NNP cord-006870-f5w6fw6q 6634 15 dose dose NNP cord-006870-f5w6fw6q 6634 16 titration titration NN cord-006870-f5w6fw6q 6634 17 . . . cord-006870-f5w6fw6q 6635 1 Further further RB cord-006870-f5w6fw6q 6635 2 , , , cord-006870-f5w6fw6q 6635 3 it -PRON- PRP cord-006870-f5w6fw6q 6635 4 may may MD cord-006870-f5w6fw6q 6635 5 be be VB cord-006870-f5w6fw6q 6635 6 an an DT cord-006870-f5w6fw6q 6635 7 effective effective JJ cord-006870-f5w6fw6q 6635 8 tool tool NN cord-006870-f5w6fw6q 6635 9 is be VBZ cord-006870-f5w6fw6q 6635 10 research research NN cord-006870-f5w6fw6q 6635 11 studying study VBG cord-006870-f5w6fw6q 6635 12 treatments treatment NNS cord-006870-f5w6fw6q 6635 13 of of IN cord-006870-f5w6fw6q 6635 14 cerebral cerebral JJ cord-006870-f5w6fw6q 6635 15 vasospasm vasospasm NN cord-006870-f5w6fw6q 6635 16 Repetitive repetitive JJ cord-006870-f5w6fw6q 6635 17 transcranial transcranial JJ cord-006870-f5w6fw6q 6635 18 magnetic magnetic JJ cord-006870-f5w6fw6q 6635 19 stimulation stimulation NN cord-006870-f5w6fw6q 6635 20 ( ( -LRB- cord-006870-f5w6fw6q 6635 21 rTMS rtms NN cord-006870-f5w6fw6q 6635 22 ) ) -RRB- cord-006870-f5w6fw6q 6635 23 is be VBZ cord-006870-f5w6fw6q 6635 24 increasingly increasingly RB cord-006870-f5w6fw6q 6635 25 used use VBN cord-006870-f5w6fw6q 6635 26 in in IN cord-006870-f5w6fw6q 6635 27 treatment treatment NN cord-006870-f5w6fw6q 6635 28 of of IN cord-006870-f5w6fw6q 6635 29 various various JJ cord-006870-f5w6fw6q 6635 30 conditions condition NNS cord-006870-f5w6fw6q 6635 31 including include VBG cord-006870-f5w6fw6q 6635 32 depression depression NN cord-006870-f5w6fw6q 6635 33 , , , cord-006870-f5w6fw6q 6635 34 chronic chronic JJ cord-006870-f5w6fw6q 6635 35 pain pain NN cord-006870-f5w6fw6q 6635 36 , , , cord-006870-f5w6fw6q 6635 37 and and CC cord-006870-f5w6fw6q 6635 38 movement movement NN cord-006870-f5w6fw6q 6635 39 disorders disorder NNS cord-006870-f5w6fw6q 6635 40 . . . cord-006870-f5w6fw6q 6636 1 The the DT cord-006870-f5w6fw6q 6636 2 use use NN cord-006870-f5w6fw6q 6636 3 of of IN cord-006870-f5w6fw6q 6636 4 rTMS rtms NN cord-006870-f5w6fw6q 6636 5 for for IN cord-006870-f5w6fw6q 6636 6 chronic chronic JJ cord-006870-f5w6fw6q 6636 7 management management NN cord-006870-f5w6fw6q 6636 8 of of IN cord-006870-f5w6fw6q 6636 9 medically medically RB cord-006870-f5w6fw6q 6636 10 refractory refractory JJ cord-006870-f5w6fw6q 6636 11 epilepsy epilepsy NN cord-006870-f5w6fw6q 6636 12 has have VBZ cord-006870-f5w6fw6q 6636 13 grown grow VBN cord-006870-f5w6fw6q 6636 14 substantially substantially RB cord-006870-f5w6fw6q 6636 15 in in IN cord-006870-f5w6fw6q 6636 16 the the DT cord-006870-f5w6fw6q 6636 17 last last JJ cord-006870-f5w6fw6q 6636 18 15 15 CD cord-006870-f5w6fw6q 6636 19 years year NNS cord-006870-f5w6fw6q 6636 20 . . . cord-006870-f5w6fw6q 6637 1 However however RB cord-006870-f5w6fw6q 6637 2 , , , cord-006870-f5w6fw6q 6637 3 little little JJ cord-006870-f5w6fw6q 6637 4 literature literature NN cord-006870-f5w6fw6q 6637 5 exists exist VBZ cord-006870-f5w6fw6q 6637 6 on on IN cord-006870-f5w6fw6q 6637 7 use use NN cord-006870-f5w6fw6q 6637 8 of of IN cord-006870-f5w6fw6q 6637 9 rTMS rtms NN cord-006870-f5w6fw6q 6637 10 for for IN cord-006870-f5w6fw6q 6637 11 acute acute JJ cord-006870-f5w6fw6q 6637 12 status status NN cord-006870-f5w6fw6q 6637 13 epilepticus epilepticus NN cord-006870-f5w6fw6q 6637 14 . . . cord-006870-f5w6fw6q 6638 1 The the DT cord-006870-f5w6fw6q 6638 2 exact exact JJ cord-006870-f5w6fw6q 6638 3 antiepileptic antiepileptic JJ cord-006870-f5w6fw6q 6638 4 mechanism mechanism NN cord-006870-f5w6fw6q 6638 5 of of IN cord-006870-f5w6fw6q 6638 6 rTMS rTMS NNP cord-006870-f5w6fw6q 6638 7 remains remain VBZ cord-006870-f5w6fw6q 6638 8 unclear unclear JJ cord-006870-f5w6fw6q 6638 9 , , , cord-006870-f5w6fw6q 6638 10 but but CC cord-006870-f5w6fw6q 6638 11 may may MD cord-006870-f5w6fw6q 6638 12 be be VB cord-006870-f5w6fw6q 6638 13 secondary secondary JJ cord-006870-f5w6fw6q 6638 14 to to IN cord-006870-f5w6fw6q 6638 15 inhibition inhibition NN cord-006870-f5w6fw6q 6638 16 of of IN cord-006870-f5w6fw6q 6638 17 cortical cortical JJ cord-006870-f5w6fw6q 6638 18 excitability excitability NN cord-006870-f5w6fw6q 6638 19 . . . cord-006870-f5w6fw6q 6639 1 We -PRON- PRP cord-006870-f5w6fw6q 6639 2 report report VBP cord-006870-f5w6fw6q 6639 3 promising promise VBG cord-006870-f5w6fw6q 6639 4 response response NN cord-006870-f5w6fw6q 6639 5 to to IN cord-006870-f5w6fw6q 6639 6 rTMS rtms NN cord-006870-f5w6fw6q 6639 7 in in IN cord-006870-f5w6fw6q 6639 8 a a DT cord-006870-f5w6fw6q 6639 9 case case NN cord-006870-f5w6fw6q 6639 10 of of IN cord-006870-f5w6fw6q 6639 11 super super JJ cord-006870-f5w6fw6q 6639 12 - - JJ cord-006870-f5w6fw6q 6639 13 refractory refractory JJ cord-006870-f5w6fw6q 6639 14 focal focal JJ cord-006870-f5w6fw6q 6639 15 status status NN cord-006870-f5w6fw6q 6639 16 epilepticus epilepticus NN cord-006870-f5w6fw6q 6639 17 . . . cord-006870-f5w6fw6q 6640 1 The the DT cord-006870-f5w6fw6q 6640 2 study study NN cord-006870-f5w6fw6q 6640 3 is be VBZ cord-006870-f5w6fw6q 6640 4 a a DT cord-006870-f5w6fw6q 6640 5 case case NN cord-006870-f5w6fw6q 6640 6 report report NN cord-006870-f5w6fw6q 6640 7 . . . cord-006870-f5w6fw6q 6641 1 A a DT cord-006870-f5w6fw6q 6641 2 daily daily JJ cord-006870-f5w6fw6q 6641 3 dose dose NN cord-006870-f5w6fw6q 6641 4 of of IN cord-006870-f5w6fw6q 6641 5 1800 1800 CD cord-006870-f5w6fw6q 6641 6 pulses pulse NNS cord-006870-f5w6fw6q 6641 7 of of IN cord-006870-f5w6fw6q 6641 8 1Hz 1hz NN cord-006870-f5w6fw6q 6641 9 rTMS rTMS NNP cord-006870-f5w6fw6q 6641 10 was be VBD cord-006870-f5w6fw6q 6641 11 applied apply VBN cord-006870-f5w6fw6q 6641 12 to to IN cord-006870-f5w6fw6q 6641 13 the the DT cord-006870-f5w6fw6q 6641 14 left left JJ cord-006870-f5w6fw6q 6641 15 occipital occipital JJ cord-006870-f5w6fw6q 6641 16 lobe lobe NN cord-006870-f5w6fw6q 6641 17 . . . cord-006870-f5w6fw6q 6642 1 Treatment treatment NN cord-006870-f5w6fw6q 6642 2 course course NN cord-006870-f5w6fw6q 6642 3 was be VBD cord-006870-f5w6fw6q 6642 4 divided divide VBN cord-006870-f5w6fw6q 6642 5 into into IN cord-006870-f5w6fw6q 6642 6 3 3 CD cord-006870-f5w6fw6q 6642 7 periods period NNS cord-006870-f5w6fw6q 6642 8 of of IN cord-006870-f5w6fw6q 6642 9 3 3 CD cord-006870-f5w6fw6q 6642 10 - - SYM cord-006870-f5w6fw6q 6642 11 5 5 CD cord-006870-f5w6fw6q 6642 12 consecutive consecutive JJ cord-006870-f5w6fw6q 6642 13 days day NNS cord-006870-f5w6fw6q 6642 14 each each DT cord-006870-f5w6fw6q 6642 15 for for IN cord-006870-f5w6fw6q 6642 16 a a DT cord-006870-f5w6fw6q 6642 17 total total NN cord-006870-f5w6fw6q 6642 18 of of IN cord-006870-f5w6fw6q 6642 19 13 13 CD cord-006870-f5w6fw6q 6642 20 days day NNS cord-006870-f5w6fw6q 6642 21 of of IN cord-006870-f5w6fw6q 6642 22 treatment treatment NN cord-006870-f5w6fw6q 6642 23 over over IN cord-006870-f5w6fw6q 6642 24 18 18 CD cord-006870-f5w6fw6q 6642 25 days day NNS cord-006870-f5w6fw6q 6642 26 . . . cord-006870-f5w6fw6q 6643 1 A a DT cord-006870-f5w6fw6q 6643 2 63-year 63-year JJ cord-006870-f5w6fw6q 6643 3 - - HYPH cord-006870-f5w6fw6q 6643 4 old old JJ cord-006870-f5w6fw6q 6643 5 woman woman NN cord-006870-f5w6fw6q 6643 6 with with IN cord-006870-f5w6fw6q 6643 7 recent recent JJ cord-006870-f5w6fw6q 6643 8 hemiarthroplasty hemiarthroplasty NNP cord-006870-f5w6fw6q 6643 9 complicated complicate VBN cord-006870-f5w6fw6q 6643 10 by by IN cord-006870-f5w6fw6q 6643 11 wound wound NN cord-006870-f5w6fw6q 6643 12 infection infection NN cord-006870-f5w6fw6q 6643 13 presented present VBN cord-006870-f5w6fw6q 6643 14 with with IN cord-006870-f5w6fw6q 6643 15 acute acute JJ cord-006870-f5w6fw6q 6643 16 unresponsiveness unresponsiveness NN cord-006870-f5w6fw6q 6643 17 and and CC cord-006870-f5w6fw6q 6643 18 right right JJ cord-006870-f5w6fw6q 6643 19 gaze gaze NN cord-006870-f5w6fw6q 6643 20 deviation deviation NN cord-006870-f5w6fw6q 6643 21 , , , cord-006870-f5w6fw6q 6643 22 evolving evolve VBG cord-006870-f5w6fw6q 6643 23 into into IN cord-006870-f5w6fw6q 6643 24 fluctuating fluctuate VBG cord-006870-f5w6fw6q 6643 25 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6643 26 , , , cord-006870-f5w6fw6q 6643 27 word word NN cord-006870-f5w6fw6q 6643 28 finding finding NN cord-006870-f5w6fw6q 6643 29 difficulty difficulty NN cord-006870-f5w6fw6q 6643 30 , , , cord-006870-f5w6fw6q 6643 31 and and CC cord-006870-f5w6fw6q 6643 32 right right UH cord-006870-f5w6fw6q 6643 33 hemineglect hemineglect NNP cord-006870-f5w6fw6q 6643 34 . . . cord-006870-f5w6fw6q 6644 1 EEG EEG NNP cord-006870-f5w6fw6q 6644 2 revealed reveal VBD cord-006870-f5w6fw6q 6644 3 persistent persistent JJ cord-006870-f5w6fw6q 6644 4 left left JJ cord-006870-f5w6fw6q 6644 5 posterior posterior JJ cord-006870-f5w6fw6q 6644 6 quadrant quadrant JJ cord-006870-f5w6fw6q 6644 7 lateralized lateralized JJ cord-006870-f5w6fw6q 6644 8 periodic periodic JJ cord-006870-f5w6fw6q 6644 9 discharges discharge NNS cord-006870-f5w6fw6q 6644 10 ( ( -LRB- cord-006870-f5w6fw6q 6644 11 LPDs lpd NNS cord-006870-f5w6fw6q 6644 12 ) ) -RRB- cord-006870-f5w6fw6q 6644 13 , , , cord-006870-f5w6fw6q 6644 14 at at IN cord-006870-f5w6fw6q 6644 15 times time NNS cord-006870-f5w6fw6q 6644 16 evolving evolve VBG cord-006870-f5w6fw6q 6644 17 into into IN cord-006870-f5w6fw6q 6644 18 electrographic electrographic JJ cord-006870-f5w6fw6q 6644 19 seizures seizure NNS cord-006870-f5w6fw6q 6644 20 , , , cord-006870-f5w6fw6q 6644 21 and and CC cord-006870-f5w6fw6q 6644 22 positron positron NN cord-006870-f5w6fw6q 6644 23 emission emission NN cord-006870-f5w6fw6q 6644 24 tomography tomography NN cord-006870-f5w6fw6q 6644 25 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6644 26 a a DT cord-006870-f5w6fw6q 6644 27 co co NN cord-006870-f5w6fw6q 6644 28 - - JJ cord-006870-f5w6fw6q 6644 29 localized localized JJ cord-006870-f5w6fw6q 6644 30 hypermetabolic hypermetabolic NN cord-006870-f5w6fw6q 6644 31 focus focus NN cord-006870-f5w6fw6q 6644 32 . . . cord-006870-f5w6fw6q 6645 1 MRI MRI NNP cord-006870-f5w6fw6q 6645 2 revealed reveal VBD cord-006870-f5w6fw6q 6645 3 subtle subtle JJ cord-006870-f5w6fw6q 6645 4 bilateral bilateral JJ cord-006870-f5w6fw6q 6645 5 occipital occipital JJ cord-006870-f5w6fw6q 6645 6 T2 t2 NN cord-006870-f5w6fw6q 6645 7 hyperintensity hyperintensity NN cord-006870-f5w6fw6q 6645 8 without without IN cord-006870-f5w6fw6q 6645 9 diffusion diffusion NN cord-006870-f5w6fw6q 6645 10 restriction restriction NN cord-006870-f5w6fw6q 6645 11 , , , cord-006870-f5w6fw6q 6645 12 which which WDT cord-006870-f5w6fw6q 6645 13 later later RB cord-006870-f5w6fw6q 6645 14 resolved resolve VBD cord-006870-f5w6fw6q 6645 15 ; ; : cord-006870-f5w6fw6q 6645 16 cerebrospinal cerebrospinal JJ cord-006870-f5w6fw6q 6645 17 fluid fluid NN cord-006870-f5w6fw6q 6645 18 was be VBD cord-006870-f5w6fw6q 6645 19 noninflammatory noninflammatory JJ cord-006870-f5w6fw6q 6645 20 . . . cord-006870-f5w6fw6q 6646 1 Seizures seizure NNS cord-006870-f5w6fw6q 6646 2 continued continue VBD cord-006870-f5w6fw6q 6646 3 despite despite IN cord-006870-f5w6fw6q 6646 4 treatment treatment NN cord-006870-f5w6fw6q 6646 5 with with IN cord-006870-f5w6fw6q 6646 6 multiple multiple JJ cord-006870-f5w6fw6q 6646 7 AEDs aed NNS cord-006870-f5w6fw6q 6646 8 , , , cord-006870-f5w6fw6q 6646 9 burst burst VBN cord-006870-f5w6fw6q 6646 10 suppression suppression NN cord-006870-f5w6fw6q 6646 11 , , , cord-006870-f5w6fw6q 6646 12 and and CC cord-006870-f5w6fw6q 6646 13 empiric empiric JJ cord-006870-f5w6fw6q 6646 14 trial trial NN cord-006870-f5w6fw6q 6646 15 of of IN cord-006870-f5w6fw6q 6646 16 high high JJ cord-006870-f5w6fw6q 6646 17 dose dose NN cord-006870-f5w6fw6q 6646 18 corticosteroids corticosteroid NNS cord-006870-f5w6fw6q 6646 19 . . . cord-006870-f5w6fw6q 6647 1 The the DT cord-006870-f5w6fw6q 6647 2 patient patient NN cord-006870-f5w6fw6q 6647 3 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6647 4 abrupt abrupt JJ cord-006870-f5w6fw6q 6647 5 electrographic electrographic JJ cord-006870-f5w6fw6q 6647 6 and and CC cord-006870-f5w6fw6q 6647 7 clinical clinical JJ cord-006870-f5w6fw6q 6647 8 improvement improvement NN cord-006870-f5w6fw6q 6647 9 after after IN cord-006870-f5w6fw6q 6647 10 rTMS rTMS NNP cord-006870-f5w6fw6q 6647 11 initiation initiation NN cord-006870-f5w6fw6q 6647 12 . . . cord-006870-f5w6fw6q 6648 1 Previously previously RB cord-006870-f5w6fw6q 6648 2 unseen unseen JJ cord-006870-f5w6fw6q 6648 3 brief brief JJ cord-006870-f5w6fw6q 6648 4 periods period NNS cord-006870-f5w6fw6q 6648 5 of of IN cord-006870-f5w6fw6q 6648 6 LPD LPD NNP cord-006870-f5w6fw6q 6648 7 resolution resolution NN cord-006870-f5w6fw6q 6648 8 were be VBD cord-006870-f5w6fw6q 6648 9 observed observe VBN cord-006870-f5w6fw6q 6648 10 within within IN cord-006870-f5w6fw6q 6648 11 30 30 CD cord-006870-f5w6fw6q 6648 12 minutes minute NNS cord-006870-f5w6fw6q 6648 13 after after IN cord-006870-f5w6fw6q 6648 14 first first JJ cord-006870-f5w6fw6q 6648 15 TMS TMS NNP cord-006870-f5w6fw6q 6648 16 session session NN cord-006870-f5w6fw6q 6648 17 with with IN cord-006870-f5w6fw6q 6648 18 further further JJ cord-006870-f5w6fw6q 6648 19 improvement improvement NN cord-006870-f5w6fw6q 6648 20 in in IN cord-006870-f5w6fw6q 6648 21 EEG EEG NNP cord-006870-f5w6fw6q 6648 22 background background NN cord-006870-f5w6fw6q 6648 23 correlating correlate VBG cord-006870-f5w6fw6q 6648 24 with with IN cord-006870-f5w6fw6q 6648 25 improvement improvement NN cord-006870-f5w6fw6q 6648 26 in in IN cord-006870-f5w6fw6q 6648 27 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6648 28 and and CC cord-006870-f5w6fw6q 6648 29 clinical clinical JJ cord-006870-f5w6fw6q 6648 30 findings finding NNS cord-006870-f5w6fw6q 6648 31 over over IN cord-006870-f5w6fw6q 6648 32 subsequent subsequent JJ cord-006870-f5w6fw6q 6648 33 days day NNS cord-006870-f5w6fw6q 6648 34 . . . cord-006870-f5w6fw6q 6649 1 Given give VBN cord-006870-f5w6fw6q 6649 2 excellent excellent JJ cord-006870-f5w6fw6q 6649 3 safety safety NN cord-006870-f5w6fw6q 6649 4 profile profile NN cord-006870-f5w6fw6q 6649 5 , , , cord-006870-f5w6fw6q 6649 6 rTMS rTMS NNP cord-006870-f5w6fw6q 6649 7 may may MD cord-006870-f5w6fw6q 6649 8 be be VB cord-006870-f5w6fw6q 6649 9 useful useful JJ cord-006870-f5w6fw6q 6649 10 transitional transitional JJ cord-006870-f5w6fw6q 6649 11 therapy therapy NN cord-006870-f5w6fw6q 6649 12 in in IN cord-006870-f5w6fw6q 6649 13 management management NN cord-006870-f5w6fw6q 6649 14 of of IN cord-006870-f5w6fw6q 6649 15 some some DT cord-006870-f5w6fw6q 6649 16 cases case NNS cord-006870-f5w6fw6q 6649 17 of of IN cord-006870-f5w6fw6q 6649 18 status status NN cord-006870-f5w6fw6q 6649 19 epilepticus epilepticus NN cord-006870-f5w6fw6q 6649 20 . . . cord-006870-f5w6fw6q 6650 1 Durability durability NN cord-006870-f5w6fw6q 6650 2 of of IN cord-006870-f5w6fw6q 6650 3 efficacy efficacy NN cord-006870-f5w6fw6q 6650 4 , , , cord-006870-f5w6fw6q 6650 5 patient patient NN cord-006870-f5w6fw6q 6650 6 selection selection NN cord-006870-f5w6fw6q 6650 7 , , , cord-006870-f5w6fw6q 6650 8 and and CC cord-006870-f5w6fw6q 6650 9 optimal optimal JJ cord-006870-f5w6fw6q 6650 10 treatment treatment NN cord-006870-f5w6fw6q 6650 11 schedules schedule NNS cord-006870-f5w6fw6q 6650 12 remain remain VBP cord-006870-f5w6fw6q 6650 13 important important JJ cord-006870-f5w6fw6q 6650 14 unresolved unresolved JJ cord-006870-f5w6fw6q 6650 15 questions question NNS cord-006870-f5w6fw6q 6650 16 . . . cord-006870-f5w6fw6q 6651 1 Further further JJ cord-006870-f5w6fw6q 6651 2 study study NN cord-006870-f5w6fw6q 6651 3 is be VBZ cord-006870-f5w6fw6q 6651 4 required require VBN cord-006870-f5w6fw6q 6651 5 . . . cord-006870-f5w6fw6q 6652 1 Central Central NNP cord-006870-f5w6fw6q 6652 2 Pontine Pontine NNP cord-006870-f5w6fw6q 6652 3 Myelinolysis Myelinolysis NNP cord-006870-f5w6fw6q 6652 4 ( ( -LRB- cord-006870-f5w6fw6q 6652 5 CPM CPM NNP cord-006870-f5w6fw6q 6652 6 ) ) -RRB- cord-006870-f5w6fw6q 6652 7 occurs occur VBZ cord-006870-f5w6fw6q 6652 8 due due IN cord-006870-f5w6fw6q 6652 9 to to IN cord-006870-f5w6fw6q 6652 10 rapid rapid JJ cord-006870-f5w6fw6q 6652 11 osmotic osmotic JJ cord-006870-f5w6fw6q 6652 12 shifts shift NNS cord-006870-f5w6fw6q 6652 13 causing cause VBG cord-006870-f5w6fw6q 6652 14 demyelination demyelination NN cord-006870-f5w6fw6q 6652 15 in in IN cord-006870-f5w6fw6q 6652 16 white white JJ cord-006870-f5w6fw6q 6652 17 matter matter NN cord-006870-f5w6fw6q 6652 18 , , , cord-006870-f5w6fw6q 6652 19 typically typically RB cord-006870-f5w6fw6q 6652 20 due due JJ cord-006870-f5w6fw6q 6652 21 to to IN cord-006870-f5w6fw6q 6652 22 rapid rapid JJ cord-006870-f5w6fw6q 6652 23 correction correction NN cord-006870-f5w6fw6q 6652 24 of of IN cord-006870-f5w6fw6q 6652 25 hyponatremia hyponatremia NN cord-006870-f5w6fw6q 6652 26 mostly mostly RB cord-006870-f5w6fw6q 6652 27 in in IN cord-006870-f5w6fw6q 6652 28 setting set VBG cord-006870-f5w6fw6q 6652 29 of of IN cord-006870-f5w6fw6q 6652 30 alcoholism alcoholism NN cord-006870-f5w6fw6q 6652 31 , , , cord-006870-f5w6fw6q 6652 32 malnutrition malnutrition NN cord-006870-f5w6fw6q 6652 33 , , , cord-006870-f5w6fw6q 6652 34 and/or and/or CC cord-006870-f5w6fw6q 6652 35 liver liver NN cord-006870-f5w6fw6q 6652 36 / / SYM cord-006870-f5w6fw6q 6652 37 renal renal JJ cord-006870-f5w6fw6q 6652 38 dysfunction dysfunction NN cord-006870-f5w6fw6q 6652 39 . . . cord-006870-f5w6fw6q 6653 1 Sequelae sequela NNS cord-006870-f5w6fw6q 6653 2 may may MD cord-006870-f5w6fw6q 6653 3 include include VB cord-006870-f5w6fw6q 6653 4 cranial cranial JJ cord-006870-f5w6fw6q 6653 5 neuropathies neuropathy NNS cord-006870-f5w6fw6q 6653 6 , , , cord-006870-f5w6fw6q 6653 7 quadriparesis quadriparesis NNP cord-006870-f5w6fw6q 6653 8 , , , cord-006870-f5w6fw6q 6653 9 seizures seizure NNS cord-006870-f5w6fw6q 6653 10 , , , cord-006870-f5w6fw6q 6653 11 and and CC cord-006870-f5w6fw6q 6653 12 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6653 13 . . . cord-006870-f5w6fw6q 6654 1 No no DT cord-006870-f5w6fw6q 6654 2 specific specific JJ cord-006870-f5w6fw6q 6654 3 treatment treatment NN cord-006870-f5w6fw6q 6654 4 exists exist VBZ cord-006870-f5w6fw6q 6654 5 ; ; : cord-006870-f5w6fw6q 6654 6 literature literature NN cord-006870-f5w6fw6q 6654 7 reports report NNS cord-006870-f5w6fw6q 6654 8 indicate indicate VBP cord-006870-f5w6fw6q 6654 9 favorable favorable JJ cord-006870-f5w6fw6q 6654 10 outcomes outcome NNS cord-006870-f5w6fw6q 6654 11 in in IN cord-006870-f5w6fw6q 6654 12 only only RB cord-006870-f5w6fw6q 6654 13 50 50 CD cord-006870-f5w6fw6q 6654 14 - - SYM cord-006870-f5w6fw6q 6654 15 67 67 CD cord-006870-f5w6fw6q 6654 16 % % NN cord-006870-f5w6fw6q 6654 17 of of IN cord-006870-f5w6fw6q 6654 18 patients patient NNS cord-006870-f5w6fw6q 6654 19 . . . cord-006870-f5w6fw6q 6655 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6655 2 patient patient NN cord-006870-f5w6fw6q 6655 3 is be VBZ cord-006870-f5w6fw6q 6655 4 a a DT cord-006870-f5w6fw6q 6655 5 50 50 CD cord-006870-f5w6fw6q 6655 6 year year NN cord-006870-f5w6fw6q 6655 7 old old JJ cord-006870-f5w6fw6q 6655 8 male male NN cord-006870-f5w6fw6q 6655 9 with with IN cord-006870-f5w6fw6q 6655 10 hypertension hypertension NN cord-006870-f5w6fw6q 6655 11 , , , cord-006870-f5w6fw6q 6655 12 tobacco tobacco NN cord-006870-f5w6fw6q 6655 13 and and CC cord-006870-f5w6fw6q 6655 14 alcohol alcohol NN cord-006870-f5w6fw6q 6655 15 abuse abuse NN cord-006870-f5w6fw6q 6655 16 , , , cord-006870-f5w6fw6q 6655 17 admitted admit VBN cord-006870-f5w6fw6q 6655 18 with with IN cord-006870-f5w6fw6q 6655 19 severe severe JJ cord-006870-f5w6fw6q 6655 20 aortic aortic JJ cord-006870-f5w6fw6q 6655 21 stenosis stenosis NN cord-006870-f5w6fw6q 6655 22 , , , cord-006870-f5w6fw6q 6655 23 complicated complicate VBN cord-006870-f5w6fw6q 6655 24 by by IN cord-006870-f5w6fw6q 6655 25 alcohol alcohol NN cord-006870-f5w6fw6q 6655 26 withdrawal withdrawal NN cord-006870-f5w6fw6q 6655 27 , , , cord-006870-f5w6fw6q 6655 28 pneumonia pneumonia NN cord-006870-f5w6fw6q 6655 29 , , , cord-006870-f5w6fw6q 6655 30 and and CC cord-006870-f5w6fw6q 6655 31 acute acute JJ cord-006870-f5w6fw6q 6655 32 kidney kidney NN cord-006870-f5w6fw6q 6655 33 injury injury NN cord-006870-f5w6fw6q 6655 34 . . . cord-006870-f5w6fw6q 6656 1 He -PRON- PRP cord-006870-f5w6fw6q 6656 2 was be VBD cord-006870-f5w6fw6q 6656 3 treated treat VBN cord-006870-f5w6fw6q 6656 4 with with IN cord-006870-f5w6fw6q 6656 5 benzodiazepines benzodiazepine NNS cord-006870-f5w6fw6q 6656 6 , , , cord-006870-f5w6fw6q 6656 7 broad broad JJ cord-006870-f5w6fw6q 6656 8 spectrum spectrum NN cord-006870-f5w6fw6q 6656 9 antibiotics antibiotic NNS cord-006870-f5w6fw6q 6656 10 , , , cord-006870-f5w6fw6q 6656 11 and and CC cord-006870-f5w6fw6q 6656 12 fluid fluid JJ cord-006870-f5w6fw6q 6656 13 resuscitation resuscitation NN cord-006870-f5w6fw6q 6656 14 . . . cord-006870-f5w6fw6q 6657 1 On on IN cord-006870-f5w6fw6q 6657 2 Hospital Hospital NNP cord-006870-f5w6fw6q 6657 3 Day Day NNP cord-006870-f5w6fw6q 6657 4 ( ( -LRB- cord-006870-f5w6fw6q 6657 5 HD HD NNP cord-006870-f5w6fw6q 6657 6 ) ) -RRB- cord-006870-f5w6fw6q 6657 7 10 10 CD cord-006870-f5w6fw6q 6657 8 , , , cord-006870-f5w6fw6q 6657 9 he -PRON- PRP cord-006870-f5w6fw6q 6657 10 had have VBD cord-006870-f5w6fw6q 6657 11 to to TO cord-006870-f5w6fw6q 6657 12 be be VB cord-006870-f5w6fw6q 6657 13 intubated intubate VBN cord-006870-f5w6fw6q 6657 14 for for IN cord-006870-f5w6fw6q 6657 15 airway airway NN cord-006870-f5w6fw6q 6657 16 protection protection NN cord-006870-f5w6fw6q 6657 17 due due IN cord-006870-f5w6fw6q 6657 18 to to IN cord-006870-f5w6fw6q 6657 19 acute acute JJ cord-006870-f5w6fw6q 6657 20 confusion confusion NN cord-006870-f5w6fw6q 6657 21 and and CC cord-006870-f5w6fw6q 6657 22 quadriparesis quadriparesis NN cord-006870-f5w6fw6q 6657 23 . . . cord-006870-f5w6fw6q 6658 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6658 2 blood blood NN cord-006870-f5w6fw6q 6658 3 work work NN cord-006870-f5w6fw6q 6658 4 was be VBD cord-006870-f5w6fw6q 6658 5 notable notable JJ cord-006870-f5w6fw6q 6658 6 for for IN cord-006870-f5w6fw6q 6658 7 wide wide JJ cord-006870-f5w6fw6q 6658 8 fluctuations fluctuation NNS cord-006870-f5w6fw6q 6658 9 in in IN cord-006870-f5w6fw6q 6658 10 serum serum NN cord-006870-f5w6fw6q 6658 11 sodium sodium NN cord-006870-f5w6fw6q 6658 12 , , , cord-006870-f5w6fw6q 6658 13 from from IN cord-006870-f5w6fw6q 6658 14 131 131 CD cord-006870-f5w6fw6q 6658 15 on on IN cord-006870-f5w6fw6q 6658 16 admission admission NN cord-006870-f5w6fw6q 6658 17 to to IN cord-006870-f5w6fw6q 6658 18 155 155 CD cord-006870-f5w6fw6q 6658 19 on on IN cord-006870-f5w6fw6q 6658 20 HD7 HD7 NNP cord-006870-f5w6fw6q 6658 21 to to IN cord-006870-f5w6fw6q 6658 22 146 146 CD cord-006870-f5w6fw6q 6658 23 on on IN cord-006870-f5w6fw6q 6658 24 HD10 HD10 NNP cord-006870-f5w6fw6q 6658 25 . . . cord-006870-f5w6fw6q 6659 1 Otherwise otherwise RB cord-006870-f5w6fw6q 6659 2 , , , cord-006870-f5w6fw6q 6659 3 laboratory laboratory NN cord-006870-f5w6fw6q 6659 4 evaluation evaluation NN cord-006870-f5w6fw6q 6659 5 was be VBD cord-006870-f5w6fw6q 6659 6 remarkable remarkable JJ cord-006870-f5w6fw6q 6659 7 only only RB cord-006870-f5w6fw6q 6659 8 for for IN cord-006870-f5w6fw6q 6659 9 mildly mildly RB cord-006870-f5w6fw6q 6659 10 elevated elevate VBN cord-006870-f5w6fw6q 6659 11 AST ast NN cord-006870-f5w6fw6q 6659 12 and and CC cord-006870-f5w6fw6q 6659 13 serum serum NN cord-006870-f5w6fw6q 6659 14 creatinine creatinine NN cord-006870-f5w6fw6q 6659 15 . . . cord-006870-f5w6fw6q 6660 1 MRI MRI NNP cord-006870-f5w6fw6q 6660 2 brain brain NN cord-006870-f5w6fw6q 6660 3 2 2 CD cord-006870-f5w6fw6q 6660 4 days day NNS cord-006870-f5w6fw6q 6660 5 after after IN cord-006870-f5w6fw6q 6660 6 symptom symptom NN cord-006870-f5w6fw6q 6660 7 onset onset NN cord-006870-f5w6fw6q 6661 1 ( ( -LRB- cord-006870-f5w6fw6q 6661 2 HD12 HD12 NNP cord-006870-f5w6fw6q 6661 3 ) ) -RRB- cord-006870-f5w6fw6q 6661 4 showed show VBD cord-006870-f5w6fw6q 6661 5 DWI DWI NNP cord-006870-f5w6fw6q 6661 6 and and CC cord-006870-f5w6fw6q 6661 7 FLAIR FLAIR NNP cord-006870-f5w6fw6q 6661 8 hyperintensities hyperintensitie NNS cord-006870-f5w6fw6q 6661 9 around around IN cord-006870-f5w6fw6q 6661 10 central central JJ cord-006870-f5w6fw6q 6661 11 pons pons NNP cord-006870-f5w6fw6q 6661 12 bilaterally bilaterally RB cord-006870-f5w6fw6q 6661 13 crossing cross VBG cord-006870-f5w6fw6q 6661 14 midline midline RB cord-006870-f5w6fw6q 6661 15 . . . cord-006870-f5w6fw6q 6662 1 EEG EEG NNP cord-006870-f5w6fw6q 6662 2 showed show VBD cord-006870-f5w6fw6q 6662 3 severe severe JJ cord-006870-f5w6fw6q 6662 4 generalized generalized JJ cord-006870-f5w6fw6q 6662 5 slowing slowing NN cord-006870-f5w6fw6q 6662 6 . . . cord-006870-f5w6fw6q 6663 1 Diagnosis diagnosis NN cord-006870-f5w6fw6q 6663 2 of of IN cord-006870-f5w6fw6q 6663 3 CPM CPM NNP cord-006870-f5w6fw6q 6663 4 was be VBD cord-006870-f5w6fw6q 6663 5 made make VBN cord-006870-f5w6fw6q 6663 6 and and CC cord-006870-f5w6fw6q 6663 7 intravenous intravenous JJ cord-006870-f5w6fw6q 6663 8 immunoglobulin immunoglobulin NN cord-006870-f5w6fw6q 6663 9 ( ( -LRB- cord-006870-f5w6fw6q 6663 10 IVIG IVIG NNP cord-006870-f5w6fw6q 6663 11 ) ) -RRB- cord-006870-f5w6fw6q 6663 12 ( ( -LRB- cord-006870-f5w6fw6q 6663 13 0.4 0.4 CD cord-006870-f5w6fw6q 6663 14 g g NN cord-006870-f5w6fw6q 6663 15 / / SYM cord-006870-f5w6fw6q 6663 16 kg kg NN cord-006870-f5w6fw6q 6663 17 / / SYM cord-006870-f5w6fw6q 6663 18 day day NN cord-006870-f5w6fw6q 6663 19 for for IN cord-006870-f5w6fw6q 6663 20 5 5 CD cord-006870-f5w6fw6q 6663 21 days day NNS cord-006870-f5w6fw6q 6663 22 ) ) -RRB- cord-006870-f5w6fw6q 6663 23 was be VBD cord-006870-f5w6fw6q 6663 24 initiated initiate VBN cord-006870-f5w6fw6q 6663 25 within within IN cord-006870-f5w6fw6q 6663 26 4 4 CD cord-006870-f5w6fw6q 6663 27 days day NNS cord-006870-f5w6fw6q 6663 28 of of IN cord-006870-f5w6fw6q 6663 29 symptom symptom NN cord-006870-f5w6fw6q 6663 30 onset onset NN cord-006870-f5w6fw6q 6663 31 , , , cord-006870-f5w6fw6q 6663 32 on on IN cord-006870-f5w6fw6q 6663 33 HD HD NNP cord-006870-f5w6fw6q 6663 34 14 14 CD cord-006870-f5w6fw6q 6663 35 . . . cord-006870-f5w6fw6q 6664 1 After after IN cord-006870-f5w6fw6q 6664 2 initiation initiation NN cord-006870-f5w6fw6q 6664 3 of of IN cord-006870-f5w6fw6q 6664 4 IVIG IVIG NNP cord-006870-f5w6fw6q 6664 5 , , , cord-006870-f5w6fw6q 6664 6 patient patient NN cord-006870-f5w6fw6q 6664 7 showed show VBD cord-006870-f5w6fw6q 6664 8 rapid rapid JJ cord-006870-f5w6fw6q 6664 9 improvement improvement NN cord-006870-f5w6fw6q 6664 10 , , , cord-006870-f5w6fw6q 6664 11 first first RB cord-006870-f5w6fw6q 6664 12 noted note VBN cord-006870-f5w6fw6q 6664 13 in in IN cord-006870-f5w6fw6q 6664 14 the the DT cord-006870-f5w6fw6q 6664 15 bilateral bilateral JJ cord-006870-f5w6fw6q 6664 16 upper upper JJ cord-006870-f5w6fw6q 6664 17 extremities extremity NNS cord-006870-f5w6fw6q 6664 18 . . . cord-006870-f5w6fw6q 6665 1 By by IN cord-006870-f5w6fw6q 6665 2 HD HD NNP cord-006870-f5w6fw6q 6665 3 20 20 CD cord-006870-f5w6fw6q 6665 4 i.e. i.e. NN cord-006870-f5w6fw6q 6665 5 , , , cord-006870-f5w6fw6q 6665 6 6 6 CD cord-006870-f5w6fw6q 6665 7 days day NNS cord-006870-f5w6fw6q 6665 8 after after IN cord-006870-f5w6fw6q 6665 9 initiation initiation NN cord-006870-f5w6fw6q 6665 10 of of IN cord-006870-f5w6fw6q 6665 11 IVIG IVIG NNP cord-006870-f5w6fw6q 6665 12 , , , cord-006870-f5w6fw6q 6665 13 he -PRON- PRP cord-006870-f5w6fw6q 6665 14 was be VBD cord-006870-f5w6fw6q 6665 15 able able JJ cord-006870-f5w6fw6q 6665 16 to to TO cord-006870-f5w6fw6q 6665 17 be be VB cord-006870-f5w6fw6q 6665 18 successfully successfully RB cord-006870-f5w6fw6q 6665 19 extubated extubate VBN cord-006870-f5w6fw6q 6665 20 ; ; : cord-006870-f5w6fw6q 6665 21 and and CC cord-006870-f5w6fw6q 6665 22 he -PRON- PRP cord-006870-f5w6fw6q 6665 23 had have VBD cord-006870-f5w6fw6q 6665 24 regained regain VBN cord-006870-f5w6fw6q 6665 25 3 3 CD cord-006870-f5w6fw6q 6665 26 - - SYM cord-006870-f5w6fw6q 6665 27 4/5 4/5 CD cord-006870-f5w6fw6q 6665 28 strength strength NN cord-006870-f5w6fw6q 6665 29 in in IN cord-006870-f5w6fw6q 6665 30 all all DT cord-006870-f5w6fw6q 6665 31 extremities extremity NNS cord-006870-f5w6fw6q 6665 32 . . . cord-006870-f5w6fw6q 6666 1 Neuropsychology neuropsychology NN cord-006870-f5w6fw6q 6666 2 testing testing NN cord-006870-f5w6fw6q 6666 3 at at IN cord-006870-f5w6fw6q 6666 4 1 1 CD cord-006870-f5w6fw6q 6666 5 month month NN cord-006870-f5w6fw6q 6666 6 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6666 7 intact intact JJ cord-006870-f5w6fw6q 6666 8 cognition cognition NN cord-006870-f5w6fw6q 6666 9 . . . cord-006870-f5w6fw6q 6667 1 We -PRON- PRP cord-006870-f5w6fw6q 6667 2 describe describe VBP cord-006870-f5w6fw6q 6667 3 a a DT cord-006870-f5w6fw6q 6667 4 case case NN cord-006870-f5w6fw6q 6667 5 of of IN cord-006870-f5w6fw6q 6667 6 rapid rapid JJ cord-006870-f5w6fw6q 6667 7 clinical clinical JJ cord-006870-f5w6fw6q 6667 8 improvement improvement NN cord-006870-f5w6fw6q 6667 9 in in IN cord-006870-f5w6fw6q 6667 10 CPM CPM NNP cord-006870-f5w6fw6q 6667 11 following follow VBG cord-006870-f5w6fw6q 6667 12 treatment treatment NN cord-006870-f5w6fw6q 6667 13 with with IN cord-006870-f5w6fw6q 6667 14 IVIG IVIG NNP cord-006870-f5w6fw6q 6667 15 . . . cord-006870-f5w6fw6q 6668 1 In in IN cord-006870-f5w6fw6q 6668 2 addition addition NN cord-006870-f5w6fw6q 6668 3 to to IN cord-006870-f5w6fw6q 6668 4 ours -PRON- PRP cord-006870-f5w6fw6q 6668 5 , , , cord-006870-f5w6fw6q 6668 6 about about RB cord-006870-f5w6fw6q 6668 7 5 5 CD cord-006870-f5w6fw6q 6668 8 similar similar JJ cord-006870-f5w6fw6q 6668 9 cases case NNS cord-006870-f5w6fw6q 6668 10 have have VBP cord-006870-f5w6fw6q 6668 11 been be VBN cord-006870-f5w6fw6q 6668 12 reported report VBN cord-006870-f5w6fw6q 6668 13 , , , cord-006870-f5w6fw6q 6668 14 in in IN cord-006870-f5w6fw6q 6668 15 which which WDT cord-006870-f5w6fw6q 6668 16 beneficial beneficial JJ cord-006870-f5w6fw6q 6668 17 outcomes outcome NNS cord-006870-f5w6fw6q 6668 18 were be VBD cord-006870-f5w6fw6q 6668 19 demonstrated demonstrate VBN cord-006870-f5w6fw6q 6668 20 following follow VBG cord-006870-f5w6fw6q 6668 21 prompt prompt JJ cord-006870-f5w6fw6q 6668 22 initiation initiation NN cord-006870-f5w6fw6q 6668 23 of of IN cord-006870-f5w6fw6q 6668 24 IVIG IVIG NNP cord-006870-f5w6fw6q 6668 25 . . . cord-006870-f5w6fw6q 6669 1 One one CD cord-006870-f5w6fw6q 6669 2 proposed propose VBN cord-006870-f5w6fw6q 6669 3 theory theory NN cord-006870-f5w6fw6q 6669 4 would would MD cord-006870-f5w6fw6q 6669 5 be be VB cord-006870-f5w6fw6q 6669 6 through through IN cord-006870-f5w6fw6q 6669 7 reduction reduction NN cord-006870-f5w6fw6q 6669 8 of of IN cord-006870-f5w6fw6q 6669 9 myelinotoxic myelinotoxic NNP cord-006870-f5w6fw6q 6669 10 antibodies antibody NNS cord-006870-f5w6fw6q 6669 11 , , , cord-006870-f5w6fw6q 6669 12 thus thus RB cord-006870-f5w6fw6q 6669 13 promoting promote VBG cord-006870-f5w6fw6q 6669 14 remyelination remyelination NN cord-006870-f5w6fw6q 6669 15 . . . cord-006870-f5w6fw6q 6670 1 Few few JJ cord-006870-f5w6fw6q 6670 2 cases case NNS cord-006870-f5w6fw6q 6670 3 have have VBP cord-006870-f5w6fw6q 6670 4 reported report VBN cord-006870-f5w6fw6q 6670 5 central central JJ cord-006870-f5w6fw6q 6670 6 neuronal neuronal JJ cord-006870-f5w6fw6q 6670 7 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 6670 8 ( ( -LRB- cord-006870-f5w6fw6q 6670 9 CNH CNH NNP cord-006870-f5w6fw6q 6670 10 ) ) -RRB- cord-006870-f5w6fw6q 6670 11 secondary secondary JJ cord-006870-f5w6fw6q 6670 12 to to IN cord-006870-f5w6fw6q 6670 13 infiltrative infiltrative JJ cord-006870-f5w6fw6q 6670 14 malignancy malignancy NN cord-006870-f5w6fw6q 6670 15 or or CC cord-006870-f5w6fw6q 6670 16 autoimmune autoimmune JJ cord-006870-f5w6fw6q 6670 17 disease disease NN cord-006870-f5w6fw6q 6670 18 . . . cord-006870-f5w6fw6q 6671 1 The the DT cord-006870-f5w6fw6q 6671 2 lesion lesion NN cord-006870-f5w6fw6q 6671 3 is be VBZ cord-006870-f5w6fw6q 6671 4 usually usually RB cord-006870-f5w6fw6q 6671 5 located locate VBN cord-006870-f5w6fw6q 6671 6 at at IN cord-006870-f5w6fw6q 6671 7 the the DT cord-006870-f5w6fw6q 6671 8 pontine pontine JJ cord-006870-f5w6fw6q 6671 9 tegmentum tegmentum NN cord-006870-f5w6fw6q 6671 10 and and CC cord-006870-f5w6fw6q 6671 11 interrupts interrupt VBZ cord-006870-f5w6fw6q 6671 12 the the DT cord-006870-f5w6fw6q 6671 13 fibers fiber NNS cord-006870-f5w6fw6q 6671 14 between between IN cord-006870-f5w6fw6q 6671 15 the the DT cord-006870-f5w6fw6q 6671 16 respiratory respiratory JJ cord-006870-f5w6fw6q 6671 17 centers center NNS cord-006870-f5w6fw6q 6671 18 in in IN cord-006870-f5w6fw6q 6671 19 the the DT cord-006870-f5w6fw6q 6671 20 pons pon NNS cord-006870-f5w6fw6q 6671 21 and and CC cord-006870-f5w6fw6q 6671 22 those those DT cord-006870-f5w6fw6q 6671 23 in in IN cord-006870-f5w6fw6q 6671 24 the the DT cord-006870-f5w6fw6q 6671 25 medulla medulla NN cord-006870-f5w6fw6q 6671 26 . . . cord-006870-f5w6fw6q 6672 1 We -PRON- PRP cord-006870-f5w6fw6q 6672 2 report report VBP cord-006870-f5w6fw6q 6672 3 a a DT cord-006870-f5w6fw6q 6672 4 case case NN cord-006870-f5w6fw6q 6672 5 of of IN cord-006870-f5w6fw6q 6672 6 a a DT cord-006870-f5w6fw6q 6672 7 57 57 CD cord-006870-f5w6fw6q 6672 8 year year NN cord-006870-f5w6fw6q 6672 9 old old JJ cord-006870-f5w6fw6q 6672 10 female female NN cord-006870-f5w6fw6q 6672 11 with with IN cord-006870-f5w6fw6q 6672 12 multiple multiple JJ cord-006870-f5w6fw6q 6672 13 comorbidities comorbiditie NNS cord-006870-f5w6fw6q 6672 14 who who WP cord-006870-f5w6fw6q 6672 15 was be VBD cord-006870-f5w6fw6q 6672 16 admitted admit VBN cord-006870-f5w6fw6q 6672 17 to to IN cord-006870-f5w6fw6q 6672 18 the the DT cord-006870-f5w6fw6q 6672 19 neurocritical neurocritical JJ cord-006870-f5w6fw6q 6672 20 - - HYPH cord-006870-f5w6fw6q 6672 21 care care NN cord-006870-f5w6fw6q 6672 22 unit unit NN cord-006870-f5w6fw6q 6672 23 after after IN cord-006870-f5w6fw6q 6672 24 intra intra JJ cord-006870-f5w6fw6q 6672 25 - - JJ cord-006870-f5w6fw6q 6672 26 operative operative JJ cord-006870-f5w6fw6q 6672 27 rupture rupture NN cord-006870-f5w6fw6q 6672 28 of of IN cord-006870-f5w6fw6q 6672 29 a a DT cord-006870-f5w6fw6q 6672 30 4 4 CD cord-006870-f5w6fw6q 6672 31 mm mm NN cord-006870-f5w6fw6q 6672 32 distal distal JJ cord-006870-f5w6fw6q 6672 33 basilar basilar JJ cord-006870-f5w6fw6q 6672 34 aneurysm aneurysm NN cord-006870-f5w6fw6q 6672 35 while while IN cord-006870-f5w6fw6q 6672 36 being be VBG cord-006870-f5w6fw6q 6672 37 electively electively RB cord-006870-f5w6fw6q 6672 38 coiled coil VBN cord-006870-f5w6fw6q 6672 39 . . . cord-006870-f5w6fw6q 6673 1 An an DT cord-006870-f5w6fw6q 6673 2 external external JJ cord-006870-f5w6fw6q 6673 3 ventricular ventricular JJ cord-006870-f5w6fw6q 6673 4 drain drain NN cord-006870-f5w6fw6q 6673 5 ( ( -LRB- cord-006870-f5w6fw6q 6673 6 EVD EVD NNP cord-006870-f5w6fw6q 6673 7 ) ) -RRB- cord-006870-f5w6fw6q 6673 8 was be VBD cord-006870-f5w6fw6q 6673 9 placed place VBN cord-006870-f5w6fw6q 6673 10 due due IN cord-006870-f5w6fw6q 6673 11 to to IN cord-006870-f5w6fw6q 6673 12 early early JJ cord-006870-f5w6fw6q 6673 13 signs sign NNS cord-006870-f5w6fw6q 6673 14 of of IN cord-006870-f5w6fw6q 6673 15 ventriculomegaly ventriculomegaly NNP cord-006870-f5w6fw6q 6673 16 . . . cord-006870-f5w6fw6q 6674 1 The the DT cord-006870-f5w6fw6q 6674 2 postoperative postoperative JJ cord-006870-f5w6fw6q 6674 3 exam exam NN cord-006870-f5w6fw6q 6674 4 showed show VBD cord-006870-f5w6fw6q 6674 5 progressive progressive JJ cord-006870-f5w6fw6q 6674 6 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6674 7 , , , cord-006870-f5w6fw6q 6674 8 left leave VBD cord-006870-f5w6fw6q 6674 9 > > NFP cord-006870-f5w6fw6q 6674 10 right right JJ cord-006870-f5w6fw6q 6674 11 hemiplegia hemiplegia NN cord-006870-f5w6fw6q 6674 12 progressive progressive JJ cord-006870-f5w6fw6q 6674 13 tachypnea tachypnea NNP cord-006870-f5w6fw6q 6674 14 ( ( -LRB- cord-006870-f5w6fw6q 6674 15 rate rate NN cord-006870-f5w6fw6q 6674 16 and and CC cord-006870-f5w6fw6q 6674 17 depth depth NN cord-006870-f5w6fw6q 6674 18 ) ) -RRB- cord-006870-f5w6fw6q 6674 19 despite despite IN cord-006870-f5w6fw6q 6674 20 being be VBG cord-006870-f5w6fw6q 6674 21 on on IN cord-006870-f5w6fw6q 6674 22 assisted assist VBN cord-006870-f5w6fw6q 6674 23 mode mode NN cord-006870-f5w6fw6q 6674 24 ventilation ventilation NN cord-006870-f5w6fw6q 6674 25 leading lead VBG cord-006870-f5w6fw6q 6674 26 to to IN cord-006870-f5w6fw6q 6674 27 severe severe JJ cord-006870-f5w6fw6q 6674 28 hypocapnia hypocapnia NNP cord-006870-f5w6fw6q 6674 29 ( ( -LRB- cord-006870-f5w6fw6q 6674 30 12.8 12.8 CD cord-006870-f5w6fw6q 6674 31 mmHg mmHg NNPS cord-006870-f5w6fw6q 6674 32 ) ) -RRB- cord-006870-f5w6fw6q 6674 33 and and CC cord-006870-f5w6fw6q 6674 34 compensatory compensatory JJ cord-006870-f5w6fw6q 6674 35 renal renal JJ cord-006870-f5w6fw6q 6674 36 acidosis acidosis NN cord-006870-f5w6fw6q 6675 1 ( ( -LRB- cord-006870-f5w6fw6q 6675 2 Bicarbonate bicarbonate NN cord-006870-f5w6fw6q 6675 3 = = SYM cord-006870-f5w6fw6q 6675 4 8.5 8.5 CD cord-006870-f5w6fw6q 6675 5 mmol mmol JJ cord-006870-f5w6fw6q 6675 6 / / SYM cord-006870-f5w6fw6q 6675 7 L L NNP cord-006870-f5w6fw6q 6675 8 ) ) -RRB- cord-006870-f5w6fw6q 6675 9 to to TO cord-006870-f5w6fw6q 6675 10 maintain maintain VB cord-006870-f5w6fw6q 6675 11 normal normal JJ cord-006870-f5w6fw6q 6675 12 PH ph NN cord-006870-f5w6fw6q 6675 13 . . . cord-006870-f5w6fw6q 6676 1 Attempt attempt VB cord-006870-f5w6fw6q 6676 2 to to TO cord-006870-f5w6fw6q 6676 3 sedate sedate VB cord-006870-f5w6fw6q 6676 4 the the DT cord-006870-f5w6fw6q 6676 5 patient patient NN cord-006870-f5w6fw6q 6676 6 led lead VBN cord-006870-f5w6fw6q 6676 7 to to IN cord-006870-f5w6fw6q 6676 8 severe severe JJ cord-006870-f5w6fw6q 6676 9 metabolic metabolic JJ cord-006870-f5w6fw6q 6676 10 acidosis acidosis NN cord-006870-f5w6fw6q 6676 11 . . . cord-006870-f5w6fw6q 6677 1 Intraventricular Intraventricular NNP cord-006870-f5w6fw6q 6677 2 nicardipine nicardipine NN cord-006870-f5w6fw6q 6677 3 was be VBD cord-006870-f5w6fw6q 6677 4 started start VBN cord-006870-f5w6fw6q 6677 5 and and CC cord-006870-f5w6fw6q 6677 6 the the DT cord-006870-f5w6fw6q 6677 7 patient patient NN cord-006870-f5w6fw6q 6677 8 ventilator ventilator NN cord-006870-f5w6fw6q 6677 9 settings setting NNS cord-006870-f5w6fw6q 6677 10 were be VBD cord-006870-f5w6fw6q 6677 11 changed change VBN cord-006870-f5w6fw6q 6677 12 to to IN cord-006870-f5w6fw6q 6677 13 Bi bi JJ cord-006870-f5w6fw6q 6677 14 - - HYPH cord-006870-f5w6fw6q 6677 15 level level NN cord-006870-f5w6fw6q 6677 16 pressure pressure NN cord-006870-f5w6fw6q 6677 17 control control NN cord-006870-f5w6fw6q 6677 18 . . . cord-006870-f5w6fw6q 6678 1 Transcranial Transcranial NNP cord-006870-f5w6fw6q 6678 2 Doppler Doppler NNP cord-006870-f5w6fw6q 6678 3 ( ( -LRB- cord-006870-f5w6fw6q 6678 4 TCD TCD NNP cord-006870-f5w6fw6q 6678 5 ) ) -RRB- cord-006870-f5w6fw6q 6678 6 showed show VBD cord-006870-f5w6fw6q 6678 7 markedly markedly RB cord-006870-f5w6fw6q 6678 8 improved improve VBN cord-006870-f5w6fw6q 6678 9 vasospasms vasospasm NNS cord-006870-f5w6fw6q 6678 10 . . . cord-006870-f5w6fw6q 6679 1 The the DT cord-006870-f5w6fw6q 6679 2 patient patient JJ cord-006870-f5w6fw6q 6679 3 respiratory respiratory JJ cord-006870-f5w6fw6q 6679 4 rate rate NN cord-006870-f5w6fw6q 6679 5 and and CC cord-006870-f5w6fw6q 6679 6 , , , cord-006870-f5w6fw6q 6679 7 to to IN cord-006870-f5w6fw6q 6679 8 a a DT cord-006870-f5w6fw6q 6679 9 lesser less JJR cord-006870-f5w6fw6q 6679 10 extent extent NN cord-006870-f5w6fw6q 6679 11 , , , cord-006870-f5w6fw6q 6679 12 the the DT cord-006870-f5w6fw6q 6679 13 tidal tidal JJ cord-006870-f5w6fw6q 6679 14 volumes volume NNS cord-006870-f5w6fw6q 6679 15 improved improve VBD cord-006870-f5w6fw6q 6679 16 after after IN cord-006870-f5w6fw6q 6679 17 several several JJ cord-006870-f5w6fw6q 6679 18 days day NNS cord-006870-f5w6fw6q 6679 19 . . . cord-006870-f5w6fw6q 6680 1 Sedation sedation NN cord-006870-f5w6fw6q 6680 2 was be VBD cord-006870-f5w6fw6q 6680 3 weaned wean VBN cord-006870-f5w6fw6q 6680 4 off off RP cord-006870-f5w6fw6q 6680 5 successfully successfully RB cord-006870-f5w6fw6q 6680 6 . . . cord-006870-f5w6fw6q 6681 1 EVD EVD NNP cord-006870-f5w6fw6q 6681 2 was be VBD cord-006870-f5w6fw6q 6681 3 successfully successfully RB cord-006870-f5w6fw6q 6681 4 weaned wean VBN cord-006870-f5w6fw6q 6681 5 off off RP cord-006870-f5w6fw6q 6681 6 and and CC cord-006870-f5w6fw6q 6681 7 removed remove VBN cord-006870-f5w6fw6q 6681 8 . . . cord-006870-f5w6fw6q 6682 1 TCD TCD NNP cord-006870-f5w6fw6q 6682 2 and and CC cord-006870-f5w6fw6q 6682 3 CT CT NNP cord-006870-f5w6fw6q 6682 4 angiogram angiogram NN cord-006870-f5w6fw6q 6682 5 showed show VBD cord-006870-f5w6fw6q 6682 6 severed sever VBN cord-006870-f5w6fw6q 6682 7 basilar basilar JJ cord-006870-f5w6fw6q 6682 8 artery artery NN cord-006870-f5w6fw6q 6682 9 vasospasm vasospasm NN cord-006870-f5w6fw6q 6682 10 while while IN cord-006870-f5w6fw6q 6682 11 MRI MRI NNP cord-006870-f5w6fw6q 6682 12 done do VBN cord-006870-f5w6fw6q 6682 13 later later RB cord-006870-f5w6fw6q 6682 14 showed show VBD cord-006870-f5w6fw6q 6682 15 bilateral bilateral JJ cord-006870-f5w6fw6q 6682 16 tegmental tegmental JJ cord-006870-f5w6fw6q 6682 17 midbrain midbrain NN cord-006870-f5w6fw6q 6682 18 ischemia ischemia NN cord-006870-f5w6fw6q 6682 19 . . . cord-006870-f5w6fw6q 6683 1 One one CD cord-006870-f5w6fw6q 6683 2 case case NN cord-006870-f5w6fw6q 6683 3 has have VBZ cord-006870-f5w6fw6q 6683 4 reported report VBN cord-006870-f5w6fw6q 6683 5 acute acute JJ cord-006870-f5w6fw6q 6683 6 central central JJ cord-006870-f5w6fw6q 6683 7 neuronal neuronal JJ cord-006870-f5w6fw6q 6683 8 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 6683 9 following follow VBG cord-006870-f5w6fw6q 6683 10 left left JJ cord-006870-f5w6fw6q 6683 11 thalamic thalamic JJ cord-006870-f5w6fw6q 6683 12 bleed bleed NN cord-006870-f5w6fw6q 6683 13 while while IN cord-006870-f5w6fw6q 6683 14 another another DT cord-006870-f5w6fw6q 6683 15 reported report VBN cord-006870-f5w6fw6q 6683 16 chronic chronic JJ cord-006870-f5w6fw6q 6683 17 neuronal neuronal JJ cord-006870-f5w6fw6q 6683 18 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 6683 19 that that WDT cord-006870-f5w6fw6q 6683 20 was be VBD cord-006870-f5w6fw6q 6683 21 attributed attribute VBN cord-006870-f5w6fw6q 6683 22 to to IN cord-006870-f5w6fw6q 6683 23 old old JJ cord-006870-f5w6fw6q 6683 24 bilateral bilateral JJ cord-006870-f5w6fw6q 6683 25 lacunar lacunar NNP cord-006870-f5w6fw6q 6683 26 thalamic thalamic JJ cord-006870-f5w6fw6q 6683 27 strokes stroke NNS cord-006870-f5w6fw6q 6683 28 by by IN cord-006870-f5w6fw6q 6683 29 exclusion exclusion NN cord-006870-f5w6fw6q 6683 30 . . . cord-006870-f5w6fw6q 6684 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6684 2 case case NN cord-006870-f5w6fw6q 6684 3 is be VBZ cord-006870-f5w6fw6q 6684 4 the the DT cord-006870-f5w6fw6q 6684 5 first first JJ cord-006870-f5w6fw6q 6684 6 to to TO cord-006870-f5w6fw6q 6684 7 report report VB cord-006870-f5w6fw6q 6684 8 central central JJ cord-006870-f5w6fw6q 6684 9 neuronal neuronal JJ cord-006870-f5w6fw6q 6684 10 hyperventilation hyperventilation NN cord-006870-f5w6fw6q 6684 11 following follow VBG cord-006870-f5w6fw6q 6684 12 aneurysmal aneurysmal NNP cord-006870-f5w6fw6q 6684 13 subacrachnoid subacrachnoid NN cord-006870-f5w6fw6q 6684 14 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6684 15 that that WDT cord-006870-f5w6fw6q 6684 16 got get VBD cord-006870-f5w6fw6q 6684 17 complicated complicate VBN cord-006870-f5w6fw6q 6684 18 by by IN cord-006870-f5w6fw6q 6684 19 bilateral bilateral JJ cord-006870-f5w6fw6q 6684 20 tegmental tegmental JJ cord-006870-f5w6fw6q 6684 21 midbrain midbrain NN cord-006870-f5w6fw6q 6684 22 strokes stroke NNS cord-006870-f5w6fw6q 6684 23 . . . cord-006870-f5w6fw6q 6685 1 While while IN cord-006870-f5w6fw6q 6685 2 respiratory respiratory JJ cord-006870-f5w6fw6q 6685 3 centers center NNS cord-006870-f5w6fw6q 6685 4 are be VBP cord-006870-f5w6fw6q 6685 5 known know VBN cord-006870-f5w6fw6q 6685 6 to to TO cord-006870-f5w6fw6q 6685 7 exist exist VB cord-006870-f5w6fw6q 6685 8 in in IN cord-006870-f5w6fw6q 6685 9 the the DT cord-006870-f5w6fw6q 6685 10 medulla medulla NN cord-006870-f5w6fw6q 6685 11 and and CC cord-006870-f5w6fw6q 6685 12 the the DT cord-006870-f5w6fw6q 6685 13 pons pon NNS cord-006870-f5w6fw6q 6685 14 , , , cord-006870-f5w6fw6q 6685 15 more more RBR cord-006870-f5w6fw6q 6685 16 recent recent JJ cord-006870-f5w6fw6q 6685 17 articles article NNS cord-006870-f5w6fw6q 6685 18 have have VBP cord-006870-f5w6fw6q 6685 19 described describe VBN cord-006870-f5w6fw6q 6685 20 networks network NNS cord-006870-f5w6fw6q 6685 21 that that WDT cord-006870-f5w6fw6q 6685 22 regulate regulate VBP cord-006870-f5w6fw6q 6685 23 breathing breathing NN cord-006870-f5w6fw6q 6685 24 extending extend VBG cord-006870-f5w6fw6q 6685 25 to to IN cord-006870-f5w6fw6q 6685 26 the the DT cord-006870-f5w6fw6q 6685 27 midbrain midbrain NNP cord-006870-f5w6fw6q 6685 28 peri peri NNP cord-006870-f5w6fw6q 6685 29 - - HYPH cord-006870-f5w6fw6q 6685 30 acquiductal acquiductal JJ cord-006870-f5w6fw6q 6685 31 grey grey NN cord-006870-f5w6fw6q 6685 32 and and CC cord-006870-f5w6fw6q 6685 33 possibly possibly RB cord-006870-f5w6fw6q 6685 34 the the DT cord-006870-f5w6fw6q 6685 35 thalami thalami NNP cord-006870-f5w6fw6q 6685 36 . . . cord-006870-f5w6fw6q 6686 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6686 2 unique unique JJ cord-006870-f5w6fw6q 6686 3 case case NN cord-006870-f5w6fw6q 6686 4 supports support VBZ cord-006870-f5w6fw6q 6686 5 this this DT cord-006870-f5w6fw6q 6686 6 hypothesis hypothesis NN cord-006870-f5w6fw6q 6686 7 . . . cord-006870-f5w6fw6q 6687 1 Serotonergic serotonergic JJ cord-006870-f5w6fw6q 6687 2 and and CC cord-006870-f5w6fw6q 6687 3 atypical atypical JJ cord-006870-f5w6fw6q 6687 4 antipsychotic antipsychotic JJ cord-006870-f5w6fw6q 6687 5 drugs drug NNS cord-006870-f5w6fw6q 6687 6 are be VBP cord-006870-f5w6fw6q 6687 7 often often RB cord-006870-f5w6fw6q 6687 8 used use VBN cord-006870-f5w6fw6q 6687 9 in in IN cord-006870-f5w6fw6q 6687 10 the the DT cord-006870-f5w6fw6q 6687 11 critically critically RB cord-006870-f5w6fw6q 6687 12 ill ill JJ cord-006870-f5w6fw6q 6687 13 in in IN cord-006870-f5w6fw6q 6687 14 the the DT cord-006870-f5w6fw6q 6687 15 treatment treatment NN cord-006870-f5w6fw6q 6687 16 of of IN cord-006870-f5w6fw6q 6687 17 posttraumatic posttraumatic JJ cord-006870-f5w6fw6q 6687 18 depression depression NN cord-006870-f5w6fw6q 6687 19 and and CC cord-006870-f5w6fw6q 6687 20 anxiety anxiety NN cord-006870-f5w6fw6q 6687 21 disorders disorder NNS cord-006870-f5w6fw6q 6687 22 . . . cord-006870-f5w6fw6q 6688 1 Hyperactive hyperactive JJ cord-006870-f5w6fw6q 6688 2 delirium delirium NN cord-006870-f5w6fw6q 6688 3 may may MD cord-006870-f5w6fw6q 6688 4 mask mask VB cord-006870-f5w6fw6q 6688 5 serotonin serotonin NN cord-006870-f5w6fw6q 6688 6 syndrome syndrome NN cord-006870-f5w6fw6q 6688 7 , , , cord-006870-f5w6fw6q 6688 8 which which WDT cord-006870-f5w6fw6q 6688 9 carries carry VBZ cord-006870-f5w6fw6q 6688 10 high high JJ cord-006870-f5w6fw6q 6688 11 morbidity morbidity NN cord-006870-f5w6fw6q 6688 12 and and CC cord-006870-f5w6fw6q 6688 13 mortality mortality NN cord-006870-f5w6fw6q 6688 14 if if IN cord-006870-f5w6fw6q 6688 15 left leave VBN cord-006870-f5w6fw6q 6688 16 untreated untreated JJ cord-006870-f5w6fw6q 6688 17 . . . cord-006870-f5w6fw6q 6689 1 We -PRON- PRP cord-006870-f5w6fw6q 6689 2 describe describe VBP cord-006870-f5w6fw6q 6689 3 a a DT cord-006870-f5w6fw6q 6689 4 case case NN cord-006870-f5w6fw6q 6689 5 of of IN cord-006870-f5w6fw6q 6689 6 serotonin serotonin NN cord-006870-f5w6fw6q 6689 7 syndrome syndrome NN cord-006870-f5w6fw6q 6689 8 in in IN cord-006870-f5w6fw6q 6689 9 a a DT cord-006870-f5w6fw6q 6689 10 critically critically RB cord-006870-f5w6fw6q 6689 11 ill ill JJ cord-006870-f5w6fw6q 6689 12 patient patient NN cord-006870-f5w6fw6q 6689 13 in in IN cord-006870-f5w6fw6q 6689 14 the the DT cord-006870-f5w6fw6q 6689 15 setting setting NN cord-006870-f5w6fw6q 6689 16 of of IN cord-006870-f5w6fw6q 6689 17 surgical surgical JJ cord-006870-f5w6fw6q 6689 18 and and CC cord-006870-f5w6fw6q 6689 19 neurocritical neurocritical JJ cord-006870-f5w6fw6q 6689 20 intensive intensive JJ cord-006870-f5w6fw6q 6689 21 care care NN cord-006870-f5w6fw6q 6689 22 unit unit NN cord-006870-f5w6fw6q 6689 23 . . . cord-006870-f5w6fw6q 6690 1 A a DT cord-006870-f5w6fw6q 6690 2 56-year 56-year JJ cord-006870-f5w6fw6q 6690 3 - - HYPH cord-006870-f5w6fw6q 6690 4 old old JJ cord-006870-f5w6fw6q 6690 5 male male NN cord-006870-f5w6fw6q 6690 6 with with IN cord-006870-f5w6fw6q 6690 7 remote remote JJ cord-006870-f5w6fw6q 6690 8 trauma trauma NN cord-006870-f5w6fw6q 6690 9 presented present VBN cord-006870-f5w6fw6q 6690 10 with with IN cord-006870-f5w6fw6q 6690 11 left left JJ cord-006870-f5w6fw6q 6690 12 upper upper JJ cord-006870-f5w6fw6q 6690 13 abdominal abdominal JJ cord-006870-f5w6fw6q 6690 14 pain pain NN cord-006870-f5w6fw6q 6690 15 . . . cord-006870-f5w6fw6q 6691 1 A a DT cord-006870-f5w6fw6q 6691 2 CT CT NNP cord-006870-f5w6fw6q 6691 3 - - NN cord-006870-f5w6fw6q 6691 4 scan scan NN cord-006870-f5w6fw6q 6691 5 of of IN cord-006870-f5w6fw6q 6691 6 abdomen abdomen NN cord-006870-f5w6fw6q 6691 7 showed show VBD cord-006870-f5w6fw6q 6691 8 left leave VBN cord-006870-f5w6fw6q 6691 9 diaphragmatic diaphragmatic JJ cord-006870-f5w6fw6q 6691 10 hernia hernia NN cord-006870-f5w6fw6q 6691 11 . . . cord-006870-f5w6fw6q 6692 1 He -PRON- PRP cord-006870-f5w6fw6q 6692 2 underwent undergo VBD cord-006870-f5w6fw6q 6692 3 left left JJ cord-006870-f5w6fw6q 6692 4 thoracotomy thoracotomy NN cord-006870-f5w6fw6q 6692 5 and and CC cord-006870-f5w6fw6q 6692 6 repair repair NN cord-006870-f5w6fw6q 6692 7 of of IN cord-006870-f5w6fw6q 6692 8 diaphragmatic diaphragmatic JJ cord-006870-f5w6fw6q 6692 9 hernia hernia NN cord-006870-f5w6fw6q 6692 10 . . . cord-006870-f5w6fw6q 6693 1 His -PRON- PRP$ cord-006870-f5w6fw6q 6693 2 postoperative postoperative JJ cord-006870-f5w6fw6q 6693 3 course course NN cord-006870-f5w6fw6q 6693 4 was be VBD cord-006870-f5w6fw6q 6693 5 complicated complicate VBN cord-006870-f5w6fw6q 6693 6 by by IN cord-006870-f5w6fw6q 6693 7 sepsis sepsis NN cord-006870-f5w6fw6q 6693 8 , , , cord-006870-f5w6fw6q 6693 9 ileus ileus NN cord-006870-f5w6fw6q 6693 10 , , , cord-006870-f5w6fw6q 6693 11 and and CC cord-006870-f5w6fw6q 6693 12 aspiration aspiration NN cord-006870-f5w6fw6q 6693 13 pneumonitis pneumonitis NN cord-006870-f5w6fw6q 6693 14 . . . cord-006870-f5w6fw6q 6694 1 He -PRON- PRP cord-006870-f5w6fw6q 6694 2 was be VBD cord-006870-f5w6fw6q 6694 3 started start VBN cord-006870-f5w6fw6q 6694 4 on on IN cord-006870-f5w6fw6q 6694 5 sertraline sertraline NN cord-006870-f5w6fw6q 6694 6 and and CC cord-006870-f5w6fw6q 6694 7 quetiapine quetiapine NN cord-006870-f5w6fw6q 6694 8 for for IN cord-006870-f5w6fw6q 6694 9 stress stress NN cord-006870-f5w6fw6q 6694 10 - - HYPH cord-006870-f5w6fw6q 6694 11 induced induce VBN cord-006870-f5w6fw6q 6694 12 anxiety anxiety NN cord-006870-f5w6fw6q 6694 13 disorder disorder NN cord-006870-f5w6fw6q 6694 14 , , , cord-006870-f5w6fw6q 6694 15 depression depression NN cord-006870-f5w6fw6q 6694 16 and and CC cord-006870-f5w6fw6q 6694 17 agitation agitation NN cord-006870-f5w6fw6q 6694 18 . . . cord-006870-f5w6fw6q 6695 1 Despite despite IN cord-006870-f5w6fw6q 6695 2 increasing increase VBG cord-006870-f5w6fw6q 6695 3 doses dose NNS cord-006870-f5w6fw6q 6695 4 of of IN cord-006870-f5w6fw6q 6695 5 sertraline sertraline NN cord-006870-f5w6fw6q 6695 6 , , , cord-006870-f5w6fw6q 6695 7 patient patient NN cord-006870-f5w6fw6q 6695 8 became become VBD cord-006870-f5w6fw6q 6695 9 agitated agitated JJ cord-006870-f5w6fw6q 6695 10 , , , cord-006870-f5w6fw6q 6695 11 tremulous tremulous JJ cord-006870-f5w6fw6q 6695 12 , , , cord-006870-f5w6fw6q 6695 13 and and CC cord-006870-f5w6fw6q 6695 14 confused confused JJ cord-006870-f5w6fw6q 6695 15 . . . cord-006870-f5w6fw6q 6696 1 Physical physical JJ cord-006870-f5w6fw6q 6696 2 examination examination NN cord-006870-f5w6fw6q 6696 3 included include VBD cord-006870-f5w6fw6q 6696 4 fever fever NN cord-006870-f5w6fw6q 6696 5 , , , cord-006870-f5w6fw6q 6696 6 tachycardia tachycardia NN cord-006870-f5w6fw6q 6696 7 , , , cord-006870-f5w6fw6q 6696 8 hypertension hypertension NN cord-006870-f5w6fw6q 6696 9 , , , cord-006870-f5w6fw6q 6696 10 diaphoresis diaphoresis NN cord-006870-f5w6fw6q 6696 11 , , , cord-006870-f5w6fw6q 6696 12 dilated dilated JJ cord-006870-f5w6fw6q 6696 13 pupils pupil NNS cord-006870-f5w6fw6q 6696 14 , , , cord-006870-f5w6fw6q 6696 15 hyperactivity hyperactivity NN cord-006870-f5w6fw6q 6696 16 , , , cord-006870-f5w6fw6q 6696 17 and and CC cord-006870-f5w6fw6q 6696 18 clonus clonus NN cord-006870-f5w6fw6q 6696 19 . . . cord-006870-f5w6fw6q 6697 1 Initially initially RB cord-006870-f5w6fw6q 6697 2 considered consider VBN cord-006870-f5w6fw6q 6697 3 to to TO cord-006870-f5w6fw6q 6697 4 be be VB cord-006870-f5w6fw6q 6697 5 due due JJ cord-006870-f5w6fw6q 6697 6 to to IN cord-006870-f5w6fw6q 6697 7 hyperactive hyperactive JJ cord-006870-f5w6fw6q 6697 8 delirium delirium NN cord-006870-f5w6fw6q 6697 9 , , , cord-006870-f5w6fw6q 6697 10 these these DT cord-006870-f5w6fw6q 6697 11 manifestations manifestation NNS cord-006870-f5w6fw6q 6697 12 did do VBD cord-006870-f5w6fw6q 6697 13 not not RB cord-006870-f5w6fw6q 6697 14 improve improve VB cord-006870-f5w6fw6q 6697 15 with with IN cord-006870-f5w6fw6q 6697 16 haloperidol haloperidol NNP cord-006870-f5w6fw6q 6697 17 . . . cord-006870-f5w6fw6q 6698 1 Neurocritical Neurocritical NNP cord-006870-f5w6fw6q 6698 2 care care NN cord-006870-f5w6fw6q 6698 3 was be VBD cord-006870-f5w6fw6q 6698 4 consulted consult VBN cord-006870-f5w6fw6q 6698 5 . . . cord-006870-f5w6fw6q 6699 1 Due due IN cord-006870-f5w6fw6q 6699 2 to to IN cord-006870-f5w6fw6q 6699 3 presence presence NN cord-006870-f5w6fw6q 6699 4 of of IN cord-006870-f5w6fw6q 6699 5 hyperactivity hyperactivity NN cord-006870-f5w6fw6q 6699 6 , , , cord-006870-f5w6fw6q 6699 7 fever fever NN cord-006870-f5w6fw6q 6699 8 and and CC cord-006870-f5w6fw6q 6699 9 clonus clonus NN cord-006870-f5w6fw6q 6699 10 , , , cord-006870-f5w6fw6q 6699 11 Serotonin Serotonin NNP cord-006870-f5w6fw6q 6699 12 syndrome syndrome NN cord-006870-f5w6fw6q 6699 13 was be VBD cord-006870-f5w6fw6q 6699 14 strongly strongly RB cord-006870-f5w6fw6q 6699 15 suspected suspect VBN cord-006870-f5w6fw6q 6699 16 . . . cord-006870-f5w6fw6q 6700 1 Sertraline Sertraline NNP cord-006870-f5w6fw6q 6700 2 and and CC cord-006870-f5w6fw6q 6700 3 quetiapine quetiapine NNP cord-006870-f5w6fw6q 6700 4 was be VBD cord-006870-f5w6fw6q 6700 5 discontinued discontinue VBN cord-006870-f5w6fw6q 6700 6 and and CC cord-006870-f5w6fw6q 6700 7 cyproheptadine cyproheptadine NN cord-006870-f5w6fw6q 6700 8 added add VBD cord-006870-f5w6fw6q 6700 9 . . . cord-006870-f5w6fw6q 6701 1 Within within IN cord-006870-f5w6fw6q 6701 2 24-hours 24-hours CD cord-006870-f5w6fw6q 6701 3 his -PRON- PRP$ cord-006870-f5w6fw6q 6701 4 symptoms symptom NNS cord-006870-f5w6fw6q 6701 5 improved improve VBD cord-006870-f5w6fw6q 6701 6 and and CC cord-006870-f5w6fw6q 6701 7 Cyproheptadine Cyproheptadine NNP cord-006870-f5w6fw6q 6701 8 was be VBD cord-006870-f5w6fw6q 6701 9 tapered taper VBN cord-006870-f5w6fw6q 6701 10 over over IN cord-006870-f5w6fw6q 6701 11 10 10 CD cord-006870-f5w6fw6q 6701 12 days day NNS cord-006870-f5w6fw6q 6701 13 . . . cord-006870-f5w6fw6q 6702 1 Serotonin serotonin NN cord-006870-f5w6fw6q 6702 2 syndrome syndrome NN cord-006870-f5w6fw6q 6702 3 , , , cord-006870-f5w6fw6q 6702 4 a a DT cord-006870-f5w6fw6q 6702 5 potentially potentially RB cord-006870-f5w6fw6q 6702 6 life life NN cord-006870-f5w6fw6q 6702 7 - - HYPH cord-006870-f5w6fw6q 6702 8 threatening threaten VBG cord-006870-f5w6fw6q 6702 9 syndrome syndrome NN cord-006870-f5w6fw6q 6702 10 , , , cord-006870-f5w6fw6q 6702 11 is be VBZ cord-006870-f5w6fw6q 6702 12 manifested manifest VBN cord-006870-f5w6fw6q 6702 13 by by IN cord-006870-f5w6fw6q 6702 14 triad triad NNP cord-006870-f5w6fw6q 6702 15 of of IN cord-006870-f5w6fw6q 6702 16 mental mental JJ cord-006870-f5w6fw6q 6702 17 status status NN cord-006870-f5w6fw6q 6702 18 changes change NNS cord-006870-f5w6fw6q 6702 19 , , , cord-006870-f5w6fw6q 6702 20 neuromuscular neuromuscular NN cord-006870-f5w6fw6q 6702 21 and and CC cord-006870-f5w6fw6q 6702 22 autonomic autonomic JJ cord-006870-f5w6fw6q 6702 23 hyperactivity hyperactivity NN cord-006870-f5w6fw6q 6702 24 . . . cord-006870-f5w6fw6q 6703 1 A a DT cord-006870-f5w6fw6q 6703 2 multitude multitude NN cord-006870-f5w6fw6q 6703 3 of of IN cord-006870-f5w6fw6q 6703 4 drug drug NN cord-006870-f5w6fw6q 6703 5 combinations combination NNS cord-006870-f5w6fw6q 6703 6 can can MD cord-006870-f5w6fw6q 6703 7 result result VB cord-006870-f5w6fw6q 6703 8 in in IN cord-006870-f5w6fw6q 6703 9 Serotonin Serotonin NNP cord-006870-f5w6fw6q 6703 10 syndrome syndrome NN cord-006870-f5w6fw6q 6703 11 . . . cord-006870-f5w6fw6q 6704 1 Serotonin serotonin NN cord-006870-f5w6fw6q 6704 2 syndrome syndrome NN cord-006870-f5w6fw6q 6704 3 is be VBZ cord-006870-f5w6fw6q 6704 4 a a DT cord-006870-f5w6fw6q 6704 5 diagnosis diagnosis NN cord-006870-f5w6fw6q 6704 6 of of IN cord-006870-f5w6fw6q 6704 7 exclusion exclusion NN cord-006870-f5w6fw6q 6704 8 , , , cord-006870-f5w6fw6q 6704 9 based base VBN cord-006870-f5w6fw6q 6704 10 on on IN cord-006870-f5w6fw6q 6704 11 history history NN cord-006870-f5w6fw6q 6704 12 and and CC cord-006870-f5w6fw6q 6704 13 neurological neurological JJ cord-006870-f5w6fw6q 6704 14 examination examination NN cord-006870-f5w6fw6q 6704 15 in in IN cord-006870-f5w6fw6q 6704 16 a a DT cord-006870-f5w6fw6q 6704 17 patient patient NN cord-006870-f5w6fw6q 6704 18 taking take VBG cord-006870-f5w6fw6q 6704 19 serotonergic serotonergic JJ cord-006870-f5w6fw6q 6704 20 drug drug NN cord-006870-f5w6fw6q 6704 21 . . . cord-006870-f5w6fw6q 6705 1 5HT-2A 5ht-2a CD cord-006870-f5w6fw6q 6705 2 receptors receptor NNS cord-006870-f5w6fw6q 6705 3 are be VBP cord-006870-f5w6fw6q 6705 4 most most RBS cord-006870-f5w6fw6q 6705 5 commonly commonly RB cord-006870-f5w6fw6q 6705 6 incriminated incriminate VBN cord-006870-f5w6fw6q 6705 7 along along RB cord-006870-f5w6fw6q 6705 8 with with IN cord-006870-f5w6fw6q 6705 9 high high JJ cord-006870-f5w6fw6q 6705 10 levels level NNS cord-006870-f5w6fw6q 6705 11 of of IN cord-006870-f5w6fw6q 6705 12 norepinephrine norepinephrine NN cord-006870-f5w6fw6q 6705 13 . . . cord-006870-f5w6fw6q 6706 1 The the DT cord-006870-f5w6fw6q 6706 2 keys key NNS cord-006870-f5w6fw6q 6706 3 to to IN cord-006870-f5w6fw6q 6706 4 management management NN cord-006870-f5w6fw6q 6706 5 include include VBP cord-006870-f5w6fw6q 6706 6 discontinuation discontinuation NN cord-006870-f5w6fw6q 6706 7 of of IN cord-006870-f5w6fw6q 6706 8 all all DT cord-006870-f5w6fw6q 6706 9 serotonergic serotonergic JJ cord-006870-f5w6fw6q 6706 10 agents agent NNS cord-006870-f5w6fw6q 6706 11 , , , cord-006870-f5w6fw6q 6706 12 supportive supportive JJ cord-006870-f5w6fw6q 6706 13 care care NN cord-006870-f5w6fw6q 6706 14 , , , cord-006870-f5w6fw6q 6706 15 and and CC cord-006870-f5w6fw6q 6706 16 cyproheptadine cyproheptadine NN cord-006870-f5w6fw6q 6706 17 . . . cord-006870-f5w6fw6q 6707 1 Cyproheptadine Cyproheptadine NNP cord-006870-f5w6fw6q 6707 2 , , , cord-006870-f5w6fw6q 6707 3 a a DT cord-006870-f5w6fw6q 6707 4 potent potent JJ cord-006870-f5w6fw6q 6707 5 5HT-2A 5ht-2a CD cord-006870-f5w6fw6q 6707 6 antagonist antagonist NN cord-006870-f5w6fw6q 6707 7 , , , cord-006870-f5w6fw6q 6707 8 is be VBZ cord-006870-f5w6fw6q 6707 9 effective effective JJ cord-006870-f5w6fw6q 6707 10 in in IN cord-006870-f5w6fw6q 6707 11 ameliorating ameliorate VBG cord-006870-f5w6fw6q 6707 12 symptoms symptom NNS cord-006870-f5w6fw6q 6707 13 . . . cord-006870-f5w6fw6q 6708 1 A a DT cord-006870-f5w6fw6q 6708 2 high high JJ cord-006870-f5w6fw6q 6708 3 suspicion suspicion NN cord-006870-f5w6fw6q 6708 4 for for IN cord-006870-f5w6fw6q 6708 5 diagnosis diagnosis NN cord-006870-f5w6fw6q 6708 6 is be VBZ cord-006870-f5w6fw6q 6708 7 important important JJ cord-006870-f5w6fw6q 6708 8 for for IN cord-006870-f5w6fw6q 6708 9 reducing reduce VBG cord-006870-f5w6fw6q 6708 10 morbidity morbidity NN cord-006870-f5w6fw6q 6708 11 and and CC cord-006870-f5w6fw6q 6708 12 mortality mortality NN cord-006870-f5w6fw6q 6708 13 associated associate VBN cord-006870-f5w6fw6q 6708 14 with with IN cord-006870-f5w6fw6q 6708 15 this this DT cord-006870-f5w6fw6q 6708 16 neurologic neurologic JJ cord-006870-f5w6fw6q 6708 17 syndrome syndrome NN cord-006870-f5w6fw6q 6708 18 in in IN cord-006870-f5w6fw6q 6708 19 the the DT cord-006870-f5w6fw6q 6708 20 critically critically RB cord-006870-f5w6fw6q 6708 21 ill ill JJ cord-006870-f5w6fw6q 6708 22 . . . cord-006870-f5w6fw6q 6709 1 Ruptured ruptured JJ cord-006870-f5w6fw6q 6709 2 cerebral cerebral JJ cord-006870-f5w6fw6q 6709 3 mycotic mycotic JJ cord-006870-f5w6fw6q 6709 4 aneurysm aneurysm NN cord-006870-f5w6fw6q 6709 5 as as IN cord-006870-f5w6fw6q 6709 6 consequence consequence NN cord-006870-f5w6fw6q 6709 7 of of IN cord-006870-f5w6fw6q 6709 8 Infective Infective NNP cord-006870-f5w6fw6q 6709 9 Endocarditis Endocarditis NNP cord-006870-f5w6fw6q 6709 10 ( ( -LRB- cord-006870-f5w6fw6q 6709 11 IE IE NNP cord-006870-f5w6fw6q 6709 12 ) ) -RRB- cord-006870-f5w6fw6q 6709 13 : : : cord-006870-f5w6fw6q 6710 1 A a DT cord-006870-f5w6fw6q 6710 2 management management NN cord-006870-f5w6fw6q 6710 3 QEEG QEEG NNP cord-006870-f5w6fw6q 6710 4 ADR ADR NNP cord-006870-f5w6fw6q 6710 5 in in IN cord-006870-f5w6fw6q 6710 6 Poor Poor NNP cord-006870-f5w6fw6q 6710 7 Grade Grade NNP cord-006870-f5w6fw6q 6710 8 SAH SAH NNP cord-006870-f5w6fw6q 6710 9 : : : cord-006870-f5w6fw6q 6710 10 Is be VBZ cord-006870-f5w6fw6q 6710 11 it -PRON- PRP cord-006870-f5w6fw6q 6710 12 Really really RB cord-006870-f5w6fw6q 6710 13 Useful useful JJ cord-006870-f5w6fw6q 6710 14 ? ? . cord-006870-f5w6fw6q 6711 1 Recognize recognize VB cord-006870-f5w6fw6q 6711 2 the the DT cord-006870-f5w6fw6q 6711 3 Various various JJ cord-006870-f5w6fw6q 6711 4 Subtypes Subtypes NNPS cord-006870-f5w6fw6q 6711 5 of of IN cord-006870-f5w6fw6q 6711 6 Cerebral Cerebral NNP cord-006870-f5w6fw6q 6711 7 Amyloid Amyloid NNP cord-006870-f5w6fw6q 6711 8 Angiopathy Angiopathy NNP cord-006870-f5w6fw6q 6711 9 Bilal Bilal NNP cord-006870-f5w6fw6q 6711 10 Butt Butt NNP cord-006870-f5w6fw6q 6711 11 Baylor Baylor NNP cord-006870-f5w6fw6q 6711 12 College College NNP cord-006870-f5w6fw6q 6711 13 of of IN cord-006870-f5w6fw6q 6711 14 Medicine Medicine NNP cord-006870-f5w6fw6q 6711 15 24-hour 24-hour NNP cord-006870-f5w6fw6q 6711 16 Development Development NNP cord-006870-f5w6fw6q 6711 17 of of IN cord-006870-f5w6fw6q 6711 18 a a DT cord-006870-f5w6fw6q 6711 19 Giant Giant NNP cord-006870-f5w6fw6q 6711 20 Infectious infectious JJ cord-006870-f5w6fw6q 6711 21 Intracranial Intracranial NNP cord-006870-f5w6fw6q 6711 22 Aneurysm Aneurysm NNP cord-006870-f5w6fw6q 6711 23 : : : cord-006870-f5w6fw6q 6712 1 A a DT cord-006870-f5w6fw6q 6712 2 Case Case NNP cord-006870-f5w6fw6q 6712 3 Report Report NNP cord-006870-f5w6fw6q 6712 4 Catherine Catherine NNP cord-006870-f5w6fw6q 6712 5 Albin Albin NNP cord-006870-f5w6fw6q 6712 6 Intra Intra NNP cord-006870-f5w6fw6q 6712 7 - - JJ cord-006870-f5w6fw6q 6712 8 operative operative JJ cord-006870-f5w6fw6q 6712 9 Ultrasound Ultrasound NNP cord-006870-f5w6fw6q 6712 10 in in IN cord-006870-f5w6fw6q 6712 11 traumatic traumatic JJ cord-006870-f5w6fw6q 6712 12 brain brain NN cord-006870-f5w6fw6q 6712 13 injury injury NN cord-006870-f5w6fw6q 6712 14 patients patient NNS cord-006870-f5w6fw6q 6713 1 Namkyu Namkyu NNP cord-006870-f5w6fw6q 6713 2 You -PRON- PRP cord-006870-f5w6fw6q 6713 3 Syndrome Syndrome NNP cord-006870-f5w6fw6q 6713 4 of of IN cord-006870-f5w6fw6q 6713 5 the the DT cord-006870-f5w6fw6q 6713 6 trepheined trepheined JJ cord-006870-f5w6fw6q 6713 7 ( ( -LRB- cord-006870-f5w6fw6q 6713 8 SoT SoT NNP cord-006870-f5w6fw6q 6713 9 ) ) -RRB- cord-006870-f5w6fw6q 6713 10 and and CC cord-006870-f5w6fw6q 6713 11 paradoxical paradoxical JJ cord-006870-f5w6fw6q 6713 12 herniation herniation NN cord-006870-f5w6fw6q 6713 13 without without IN cord-006870-f5w6fw6q 6713 14 craniectomy craniectomy NNP cord-006870-f5w6fw6q 6713 15 Elysia Elysia NNP cord-006870-f5w6fw6q 6713 16 James James NNP cord-006870-f5w6fw6q 6713 17 Spectrum Spectrum NNP cord-006870-f5w6fw6q 6714 1 Health Health NNP cord-006870-f5w6fw6q 6714 2 Neurosciences Neurosciences NNP cord-006870-f5w6fw6q 6714 3 -ICU -icu POS cord-006870-f5w6fw6q 6714 4 Division Division NNP cord-006870-f5w6fw6q 6714 5 Stephen Stephen NNP cord-006870-f5w6fw6q 6714 6 A. A. NNP cord-006870-f5w6fw6q 6714 7 Trevick Trevick NNP cord-006870-f5w6fw6q 6714 8 1 1 CD cord-006870-f5w6fw6q 6714 9 , , , cord-006870-f5w6fw6q 6714 10 Andrew Andrew NNP cord-006870-f5w6fw6q 6714 11 Naidech Naidech NNP cord-006870-f5w6fw6q 6714 12 2 2 CD cord-006870-f5w6fw6q 6714 13 , , , cord-006870-f5w6fw6q 6714 14 Leah Leah NNP cord-006870-f5w6fw6q 6714 15 Tatebe Tatebe NNP cord-006870-f5w6fw6q 6714 16 _SP cord-006870-f5w6fw6q 6715 1 2672 2672 CD cord-006870-f5w6fw6q 6715 2 patients patient NNS cord-006870-f5w6fw6q 6715 3 were be VBD cord-006870-f5w6fw6q 6715 4 included include VBN cord-006870-f5w6fw6q 6715 5 . . . cord-006870-f5w6fw6q 6716 1 Median median JJ cord-006870-f5w6fw6q 6716 2 age age NN cord-006870-f5w6fw6q 6716 3 was be VBD cord-006870-f5w6fw6q 6716 4 54 54 CD cord-006870-f5w6fw6q 6716 5 years year NNS cord-006870-f5w6fw6q 6716 6 . . . cord-006870-f5w6fw6q 6717 1 66 66 CD cord-006870-f5w6fw6q 6717 2 % % NN cord-006870-f5w6fw6q 6717 3 were be VBD cord-006870-f5w6fw6q 6717 4 female female JJ cord-006870-f5w6fw6q 6717 5 , , , cord-006870-f5w6fw6q 6717 6 26 26 CD cord-006870-f5w6fw6q 6717 7 % % NN cord-006870-f5w6fw6q 6717 8 smokers smoker NNS cord-006870-f5w6fw6q 6717 9 , , , cord-006870-f5w6fw6q 6717 10 54 54 CD cord-006870-f5w6fw6q 6717 11 % % NN cord-006870-f5w6fw6q 6717 12 hypertensive hypertensive JJ cord-006870-f5w6fw6q 6717 13 and and CC cord-006870-f5w6fw6q 6717 14 12 12 CD cord-006870-f5w6fw6q 6717 15 % % NN cord-006870-f5w6fw6q 6717 16 diabetic diabetic JJ cord-006870-f5w6fw6q 6717 17 . . . cord-006870-f5w6fw6q 6718 1 8 8 CD cord-006870-f5w6fw6q 6718 2 % % NN cord-006870-f5w6fw6q 6718 3 had have VBD cord-006870-f5w6fw6q 6718 4 a a DT cord-006870-f5w6fw6q 6718 5 history history NN cord-006870-f5w6fw6q 6718 6 of of IN cord-006870-f5w6fw6q 6718 7 CAD CAD NNP cord-006870-f5w6fw6q 6718 8 or or CC cord-006870-f5w6fw6q 6718 9 MI MI NNP cord-006870-f5w6fw6q 6718 10 and and CC cord-006870-f5w6fw6q 6718 11 14 14 CD cord-006870-f5w6fw6q 6718 12 % % NN cord-006870-f5w6fw6q 6718 13 had have VBD cord-006870-f5w6fw6q 6718 14 hyperlipidemia hyperlipidemia NN cord-006870-f5w6fw6q 6718 15 . . . cord-006870-f5w6fw6q 6719 1 In in IN cord-006870-f5w6fw6q 6719 2 the the DT cord-006870-f5w6fw6q 6719 3 multivariable multivariable JJ cord-006870-f5w6fw6q 6719 4 analysis analysis NN cord-006870-f5w6fw6q 6719 5 , , , cord-006870-f5w6fw6q 6719 6 the the DT cord-006870-f5w6fw6q 6719 7 odds odd NNS cord-006870-f5w6fw6q 6719 8 ratio ratio NN cord-006870-f5w6fw6q 6719 9 for for IN cord-006870-f5w6fw6q 6719 10 unfavorable unfavorable JJ cord-006870-f5w6fw6q 6719 11 outcome outcome NN cord-006870-f5w6fw6q 6719 12 , , , cord-006870-f5w6fw6q 6719 13 defined define VBN cord-006870-f5w6fw6q 6719 14 as as IN cord-006870-f5w6fw6q 6719 15 mRS mrs DT cord-006870-f5w6fw6q 6719 16 score score NN cord-006870-f5w6fw6q 6719 17 of of IN cord-006870-f5w6fw6q 6719 18 3 3 CD cord-006870-f5w6fw6q 6719 19 - - SYM cord-006870-f5w6fw6q 6719 20 6 6 CD cord-006870-f5w6fw6q 6719 21 , , , cord-006870-f5w6fw6q 6719 22 was be VBD cord-006870-f5w6fw6q 6719 23 5.7(95%C.I 5.7(95%c.i CD cord-006870-f5w6fw6q 6719 24 : : : cord-006870-f5w6fw6q 6719 25 4.6 4.6 CD cord-006870-f5w6fw6q 6719 26 - - SYM cord-006870-f5w6fw6q 6719 27 7.0 7.0 CD cord-006870-f5w6fw6q 6719 28 ) ) -RRB- cord-006870-f5w6fw6q 6719 29 and and CC cord-006870-f5w6fw6q 6719 30 66.0(95%CI 66.0(95%ci CD cord-006870-f5w6fw6q 6719 31 : : : cord-006870-f5w6fw6q 6719 32 44.0 44.0 CD cord-006870-f5w6fw6q 6719 33 - - HYPH cord-006870-f5w6fw6q 6719 34 99.1 99.1 CD cord-006870-f5w6fw6q 6719 35 ) ) -RRB- cord-006870-f5w6fw6q 6719 36 for for IN cord-006870-f5w6fw6q 6719 37 the the DT cord-006870-f5w6fw6q 6719 38 intermediate intermediate NN cord-006870-f5w6fw6q 6719 39 - - : cord-006870-f5w6fw6q 6719 40 grade(III grade(iii ADD cord-006870-f5w6fw6q 6719 41 ) ) -RRB- cord-006870-f5w6fw6q 6719 42 and and CC cord-006870-f5w6fw6q 6719 43 high high RB cord-006870-f5w6fw6q 6719 44 - - HYPH cord-006870-f5w6fw6q 6719 45 grade(IV grade(iv NN cord-006870-f5w6fw6q 6719 46 and and CC cord-006870-f5w6fw6q 6719 47 V v NN cord-006870-f5w6fw6q 6719 48 ) ) -RRB- cord-006870-f5w6fw6q 6719 49 HH hh NN cord-006870-f5w6fw6q 6719 50 groups group NNS cord-006870-f5w6fw6q 6719 51 respectively respectively RB cord-006870-f5w6fw6q 6719 52 , , , cord-006870-f5w6fw6q 6719 53 when when WRB cord-006870-f5w6fw6q 6719 54 compared compare VBN cord-006870-f5w6fw6q 6719 55 to to IN cord-006870-f5w6fw6q 6719 56 the the DT cord-006870-f5w6fw6q 6719 57 low low JJ cord-006870-f5w6fw6q 6719 58 - - HYPH cord-006870-f5w6fw6q 6719 59 grade(I grade(i NN cord-006870-f5w6fw6q 6719 60 and and CC cord-006870-f5w6fw6q 6719 61 II II NNP cord-006870-f5w6fw6q 6719 62 ) ) -RRB- cord-006870-f5w6fw6q 6719 63 HH HH NNP cord-006870-f5w6fw6q 6719 64 group group NN cord-006870-f5w6fw6q 6719 65 . . . cord-006870-f5w6fw6q 6720 1 Age age NN cord-006870-f5w6fw6q 6720 2 , , , cord-006870-f5w6fw6q 6720 3 hypertension hypertension NN cord-006870-f5w6fw6q 6720 4 and and CC cord-006870-f5w6fw6q 6720 5 diabetes diabetes NN cord-006870-f5w6fw6q 6720 6 were be VBD cord-006870-f5w6fw6q 6720 7 found find VBN cord-006870-f5w6fw6q 6720 8 to to TO cord-006870-f5w6fw6q 6720 9 be be VB cord-006870-f5w6fw6q 6720 10 negatively negatively RB cord-006870-f5w6fw6q 6720 11 associated associate VBN cord-006870-f5w6fw6q 6720 12 with with IN cord-006870-f5w6fw6q 6720 13 mRS mrs XX cord-006870-f5w6fw6q 6720 14 , , , cord-006870-f5w6fw6q 6720 15 while while IN cord-006870-f5w6fw6q 6720 16 hyperlipidemia hyperlipidemia NN cord-006870-f5w6fw6q 6720 17 was be VBD cord-006870-f5w6fw6q 6720 18 positively positively RB cord-006870-f5w6fw6q 6720 19 associated associate VBN cord-006870-f5w6fw6q 6720 20 . . . cord-006870-f5w6fw6q 6721 1 Gender gender NN cord-006870-f5w6fw6q 6721 2 , , , cord-006870-f5w6fw6q 6721 3 race race NN cord-006870-f5w6fw6q 6721 4 , , , cord-006870-f5w6fw6q 6721 5 smoking smoking NN cord-006870-f5w6fw6q 6721 6 and and CC cord-006870-f5w6fw6q 6721 7 history history NN cord-006870-f5w6fw6q 6721 8 of of IN cord-006870-f5w6fw6q 6721 9 CAD CAD NNP cord-006870-f5w6fw6q 6721 10 / / SYM cord-006870-f5w6fw6q 6721 11 MI MI NNP cord-006870-f5w6fw6q 6721 12 were be VBD cord-006870-f5w6fw6q 6721 13 not not RB cord-006870-f5w6fw6q 6721 14 significantly significantly RB cord-006870-f5w6fw6q 6721 15 related relate VBN cord-006870-f5w6fw6q 6721 16 to to IN cord-006870-f5w6fw6q 6721 17 mRS mrs PRP cord-006870-f5w6fw6q 6721 18 . . . cord-006870-f5w6fw6q 6722 1 A a DT cord-006870-f5w6fw6q 6722 2 positive positive JJ cord-006870-f5w6fw6q 6722 3 trend trend NN cord-006870-f5w6fw6q 6722 4 for for IN cord-006870-f5w6fw6q 6722 5 better well JJR cord-006870-f5w6fw6q 6722 6 mRS mrs PRP$ cord-006870-f5w6fw6q 6722 7 outcome outcome NN cord-006870-f5w6fw6q 6722 8 was be VBD cord-006870-f5w6fw6q 6722 9 observed observe VBN cord-006870-f5w6fw6q 6722 10 across across IN cord-006870-f5w6fw6q 6722 11 years year NNS cord-006870-f5w6fw6q 6722 12 ( ( -LRB- cord-006870-f5w6fw6q 6722 13 p=0.008 p=0.008 NNP cord-006870-f5w6fw6q 6722 14 ) ) -RRB- cord-006870-f5w6fw6q 6722 15 . . . cord-006870-f5w6fw6q 6723 1 This this DT cord-006870-f5w6fw6q 6723 2 trend trend NN cord-006870-f5w6fw6q 6723 3 was be VBD cord-006870-f5w6fw6q 6723 4 not not RB cord-006870-f5w6fw6q 6723 5 related relate VBN cord-006870-f5w6fw6q 6723 6 to to IN cord-006870-f5w6fw6q 6723 7 HH HH NNP cord-006870-f5w6fw6q 6723 8 grade grade NN cord-006870-f5w6fw6q 6723 9 on on IN cord-006870-f5w6fw6q 6723 10 admission admission NN cord-006870-f5w6fw6q 6723 11 , , , cord-006870-f5w6fw6q 6723 12 ( ( -LRB- cord-006870-f5w6fw6q 6723 13 p=0.18 p=0.18 NN cord-006870-f5w6fw6q 6723 14 for for IN cord-006870-f5w6fw6q 6723 15 interaction interaction NN cord-006870-f5w6fw6q 6723 16 between between IN cord-006870-f5w6fw6q 6723 17 HH HH NNP cord-006870-f5w6fw6q 6723 18 grade grade NN cord-006870-f5w6fw6q 6723 19 and and CC cord-006870-f5w6fw6q 6723 20 year year NN cord-006870-f5w6fw6q 6723 21 ) ) -RRB- cord-006870-f5w6fw6q 6723 22 . . . cord-006870-f5w6fw6q 6724 1 HH HH NNP cord-006870-f5w6fw6q 6724 2 scale scale NN cord-006870-f5w6fw6q 6724 3 on on IN cord-006870-f5w6fw6q 6724 4 admission admission NN cord-006870-f5w6fw6q 6724 5 is be VBZ cord-006870-f5w6fw6q 6724 6 associated associate VBN cord-006870-f5w6fw6q 6724 7 with with IN cord-006870-f5w6fw6q 6724 8 the the DT cord-006870-f5w6fw6q 6724 9 mRS mrs JJ cord-006870-f5w6fw6q 6724 10 outcome outcome NN cord-006870-f5w6fw6q 6724 11 upon upon IN cord-006870-f5w6fw6q 6724 12 discharge discharge NN cord-006870-f5w6fw6q 6724 13 for for IN cord-006870-f5w6fw6q 6724 14 patients patient NNS cord-006870-f5w6fw6q 6724 15 with with IN cord-006870-f5w6fw6q 6724 16 nontraumatic nontraumatic JJ cord-006870-f5w6fw6q 6724 17 SAH SAH NNP cord-006870-f5w6fw6q 6724 18 . . . cord-006870-f5w6fw6q 6725 1 Models model NNS cord-006870-f5w6fw6q 6725 2 predicting predict VBG cord-006870-f5w6fw6q 6725 3 the the DT cord-006870-f5w6fw6q 6725 4 probability probability NN cord-006870-f5w6fw6q 6725 5 of of IN cord-006870-f5w6fw6q 6725 6 a a DT cord-006870-f5w6fw6q 6725 7 good good JJ cord-006870-f5w6fw6q 6725 8 mRS mrs XX cord-006870-f5w6fw6q 6725 9 outcome outcome NN cord-006870-f5w6fw6q 6725 10 could could MD cord-006870-f5w6fw6q 6725 11 be be VB cord-006870-f5w6fw6q 6725 12 created create VBN cord-006870-f5w6fw6q 6725 13 based base VBN cord-006870-f5w6fw6q 6725 14 on on IN cord-006870-f5w6fw6q 6725 15 the the DT cord-006870-f5w6fw6q 6725 16 HH HH NNP cord-006870-f5w6fw6q 6725 17 grade grade NN cord-006870-f5w6fw6q 6725 18 on on IN cord-006870-f5w6fw6q 6725 19 admission admission NN cord-006870-f5w6fw6q 6725 20 , , , cord-006870-f5w6fw6q 6725 21 age age NN cord-006870-f5w6fw6q 6725 22 , , , cord-006870-f5w6fw6q 6725 23 hypertension hypertension NN cord-006870-f5w6fw6q 6725 24 , , , cord-006870-f5w6fw6q 6725 25 diabetes diabetes NN cord-006870-f5w6fw6q 6725 26 and and CC cord-006870-f5w6fw6q 6725 27 hyperlipidemia hyperlipidemia NN cord-006870-f5w6fw6q 6725 28 status status NN cord-006870-f5w6fw6q 6725 29 . . . cord-006870-f5w6fw6q 6726 1 The the DT cord-006870-f5w6fw6q 6726 2 data datum NNS cord-006870-f5w6fw6q 6726 3 suggest suggest VBP cord-006870-f5w6fw6q 6726 4 a a DT cord-006870-f5w6fw6q 6726 5 trend trend NN cord-006870-f5w6fw6q 6726 6 toward toward IN cord-006870-f5w6fw6q 6726 7 improvement improvement NN cord-006870-f5w6fw6q 6726 8 in in IN cord-006870-f5w6fw6q 6726 9 medical medical JJ cord-006870-f5w6fw6q 6726 10 and and CC cord-006870-f5w6fw6q 6726 11 surgical surgical JJ cord-006870-f5w6fw6q 6726 12 care care NN cord-006870-f5w6fw6q 6726 13 for for IN cord-006870-f5w6fw6q 6726 14 this this DT cord-006870-f5w6fw6q 6726 15 patient patient JJ cord-006870-f5w6fw6q 6726 16 population population NN cord-006870-f5w6fw6q 6726 17 across across IN cord-006870-f5w6fw6q 6726 18 years year NNS cord-006870-f5w6fw6q 6726 19 . . . cord-006870-f5w6fw6q 6727 1 Ciro Ciro NNP cord-006870-f5w6fw6q 6727 2 _SP cord-006870-f5w6fw6q 6727 3 Poor poor JJ cord-006870-f5w6fw6q 6727 4 - - HYPH cord-006870-f5w6fw6q 6727 5 grade grade NN cord-006870-f5w6fw6q 6727 6 subarachnoid subarachnoid NN cord-006870-f5w6fw6q 6727 7 hemorrhage hemorrhage NN cord-006870-f5w6fw6q 6727 8 ( ( -LRB- cord-006870-f5w6fw6q 6727 9 SAH SAH NNP cord-006870-f5w6fw6q 6727 10 ) ) -RRB- cord-006870-f5w6fw6q 6727 11 is be VBZ cord-006870-f5w6fw6q 6727 12 associated associate VBN cord-006870-f5w6fw6q 6727 13 with with IN cord-006870-f5w6fw6q 6727 14 high high JJ cord-006870-f5w6fw6q 6727 15 mortality mortality NN cord-006870-f5w6fw6q 6727 16 rates rate NNS cord-006870-f5w6fw6q 6727 17 . . . cord-006870-f5w6fw6q 6728 1 Although although IN cord-006870-f5w6fw6q 6728 2 death death NN cord-006870-f5w6fw6q 6728 3 rates rate NNS cord-006870-f5w6fw6q 6728 4 have have VBP cord-006870-f5w6fw6q 6728 5 decreased decrease VBN cord-006870-f5w6fw6q 6728 6 in in IN cord-006870-f5w6fw6q 6728 7 the the DT cord-006870-f5w6fw6q 6728 8 last last JJ cord-006870-f5w6fw6q 6728 9 three three CD cord-006870-f5w6fw6q 6728 10 decades decade NNS cord-006870-f5w6fw6q 6728 11 , , , cord-006870-f5w6fw6q 6728 12 the the DT cord-006870-f5w6fw6q 6728 13 exact exact JJ cord-006870-f5w6fw6q 6728 14 mechanisms mechanism NNS cord-006870-f5w6fw6q 6728 15 of of IN cord-006870-f5w6fw6q 6728 16 demise demise NN cord-006870-f5w6fw6q 6728 17 are be VBP cord-006870-f5w6fw6q 6728 18 still still RB cord-006870-f5w6fw6q 6728 19 to to TO cord-006870-f5w6fw6q 6728 20 be be VB cord-006870-f5w6fw6q 6728 21 determined determine VBN cord-006870-f5w6fw6q 6728 22 in in IN cord-006870-f5w6fw6q 6728 23 this this DT cord-006870-f5w6fw6q 6728 24 patient patient JJ cord-006870-f5w6fw6q 6728 25 population population NN cord-006870-f5w6fw6q 6728 26 . . . cord-006870-f5w6fw6q 6729 1 A a DT cord-006870-f5w6fw6q 6729 2 retrospective retrospective JJ cord-006870-f5w6fw6q 6729 3 study study NN cord-006870-f5w6fw6q 6729 4 of of IN cord-006870-f5w6fw6q 6729 5 consecutive consecutive JJ cord-006870-f5w6fw6q 6729 6 poor poor JJ cord-006870-f5w6fw6q 6729 7 - - HYPH cord-006870-f5w6fw6q 6729 8 grade grade NN cord-006870-f5w6fw6q 6729 9 SAH SAH NNP cord-006870-f5w6fw6q 6729 10 patients patient NNS cord-006870-f5w6fw6q 6729 11 ( ( -LRB- cord-006870-f5w6fw6q 6729 12 World World NNP cord-006870-f5w6fw6q 6729 13 Federation Federation NNP cord-006870-f5w6fw6q 6729 14 of of IN cord-006870-f5w6fw6q 6729 15 Neurosurgical Neurosurgical NNP cord-006870-f5w6fw6q 6729 16 Societies Societies NNP cord-006870-f5w6fw6q 6729 17 grades grade NNS cord-006870-f5w6fw6q 6729 18 IV IV NNP cord-006870-f5w6fw6q 6729 19 and and CC cord-006870-f5w6fw6q 6729 20 V V NNP cord-006870-f5w6fw6q 6729 21 ) ) -RRB- cord-006870-f5w6fw6q 6729 22 aggressively aggressively RB cord-006870-f5w6fw6q 6729 23 treated treat VBN cord-006870-f5w6fw6q 6729 24 in in IN cord-006870-f5w6fw6q 6729 25 two two CD cord-006870-f5w6fw6q 6729 26 academic academic JJ cord-006870-f5w6fw6q 6729 27 high high JJ cord-006870-f5w6fw6q 6729 28 - - HYPH cord-006870-f5w6fw6q 6729 29 volume volume NN cord-006870-f5w6fw6q 6729 30 centers center NNS cord-006870-f5w6fw6q 6729 31 , , , cord-006870-f5w6fw6q 6729 32 one one CD cord-006870-f5w6fw6q 6729 33 in in IN cord-006870-f5w6fw6q 6729 34 The the DT cord-006870-f5w6fw6q 6729 35 Netherlands Netherlands NNP cord-006870-f5w6fw6q 6729 36 ( ( -LRB- cord-006870-f5w6fw6q 6729 37 AMC AMC NNP cord-006870-f5w6fw6q 6729 38 ) ) -RRB- cord-006870-f5w6fw6q 6729 39 and and CC cord-006870-f5w6fw6q 6729 40 one one CD cord-006870-f5w6fw6q 6729 41 in in IN cord-006870-f5w6fw6q 6729 42 Canada Canada NNP cord-006870-f5w6fw6q 6729 43 ( ( -LRB- cord-006870-f5w6fw6q 6729 44 SMH SMH NNP cord-006870-f5w6fw6q 6729 45 ) ) -RRB- cord-006870-f5w6fw6q 6729 46 . . . cord-006870-f5w6fw6q 6730 1 The the DT cord-006870-f5w6fw6q 6730 2 primary primary JJ cord-006870-f5w6fw6q 6730 3 outcome outcome NN cord-006870-f5w6fw6q 6730 4 was be VBD cord-006870-f5w6fw6q 6730 5 in in IN cord-006870-f5w6fw6q 6730 6 - - HYPH cord-006870-f5w6fw6q 6730 7 hospital hospital NN cord-006870-f5w6fw6q 6730 8 mortality mortality NN cord-006870-f5w6fw6q 6730 9 . . . cord-006870-f5w6fw6q 6731 1 The the DT cord-006870-f5w6fw6q 6731 2 main main JJ cord-006870-f5w6fw6q 6731 3 reasons reason NNS cord-006870-f5w6fw6q 6731 4 of of IN cord-006870-f5w6fw6q 6731 5 death death NN cord-006870-f5w6fw6q 6731 6 were be VBD cord-006870-f5w6fw6q 6731 7 evaluated evaluate VBN cord-006870-f5w6fw6q 6731 8 . . . cord-006870-f5w6fw6q 6732 1 A a DT cord-006870-f5w6fw6q 6732 2 total total NN cord-006870-f5w6fw6q 6732 3 of of IN cord-006870-f5w6fw6q 6732 4 357 357 CD cord-006870-f5w6fw6q 6732 5 poor poor JJ cord-006870-f5w6fw6q 6732 6 - - HYPH cord-006870-f5w6fw6q 6732 7 grade grade NN cord-006870-f5w6fw6q 6732 8 SAH SAH NNP cord-006870-f5w6fw6q 6732 9 patients patient NNS cord-006870-f5w6fw6q 6732 10 were be VBD cord-006870-f5w6fw6q 6732 11 admitted admit VBN cord-006870-f5w6fw6q 6732 12 between between IN cord-006870-f5w6fw6q 6732 13 2009 2009 CD cord-006870-f5w6fw6q 6732 14 and and CC cord-006870-f5w6fw6q 6732 15 2013 2013 CD cord-006870-f5w6fw6q 6732 16 , , , cord-006870-f5w6fw6q 6732 17 178 178 CD cord-006870-f5w6fw6q 6732 18 to to IN cord-006870-f5w6fw6q 6732 19 AMC AMC NNP cord-006870-f5w6fw6q 6732 20 and and CC cord-006870-f5w6fw6q 6732 21 179 179 CD cord-006870-f5w6fw6q 6732 22 to to IN cord-006870-f5w6fw6q 6732 23 SMH SMH NNP cord-006870-f5w6fw6q 6732 24 . . . cord-006870-f5w6fw6q 6733 1 152 152 CD cord-006870-f5w6fw6q 6733 2 ( ( -LRB- cord-006870-f5w6fw6q 6733 3 43 43 CD cord-006870-f5w6fw6q 6733 4 % % NN cord-006870-f5w6fw6q 6733 5 ) ) -RRB- cord-006870-f5w6fw6q 6733 6 patients patient NNS cord-006870-f5w6fw6q 6733 7 died die VBD cord-006870-f5w6fw6q 6733 8 , , , cord-006870-f5w6fw6q 6733 9 and and CC cord-006870-f5w6fw6q 6733 10 85 85 CD cord-006870-f5w6fw6q 6733 11 ( ( -LRB- cord-006870-f5w6fw6q 6733 12 24 24 CD cord-006870-f5w6fw6q 6733 13 % % NN cord-006870-f5w6fw6q 6733 14 ) ) -RRB- cord-006870-f5w6fw6q 6733 15 of of IN cord-006870-f5w6fw6q 6733 16 those those DT cord-006870-f5w6fw6q 6733 17 patients patient NNS cord-006870-f5w6fw6q 6733 18 died die VBD cord-006870-f5w6fw6q 6733 19 before before IN cord-006870-f5w6fw6q 6733 20 having have VBG cord-006870-f5w6fw6q 6733 21 the the DT cord-006870-f5w6fw6q 6733 22 culprit culprit NN cord-006870-f5w6fw6q 6733 23 aneurysm aneurysm NN cord-006870-f5w6fw6q 6733 24 treated treat VBN cord-006870-f5w6fw6q 6733 25 . . . cord-006870-f5w6fw6q 6734 1 The the DT cord-006870-f5w6fw6q 6734 2 median median JJ cord-006870-f5w6fw6q 6734 3 interval interval NN cord-006870-f5w6fw6q 6734 4 between between IN cord-006870-f5w6fw6q 6734 5 hospital hospital NN cord-006870-f5w6fw6q 6734 6 admission admission NN cord-006870-f5w6fw6q 6734 7 and and CC cord-006870-f5w6fw6q 6734 8 death death NN cord-006870-f5w6fw6q 6734 9 was be VBD cord-006870-f5w6fw6q 6734 10 three three CD cord-006870-f5w6fw6q 6734 11 days day NNS cord-006870-f5w6fw6q 6734 12 ( ( -LRB- cord-006870-f5w6fw6q 6734 13 IQR IQR NNP cord-006870-f5w6fw6q 6734 14 1 1 CD cord-006870-f5w6fw6q 6734 15 - - SYM cord-006870-f5w6fw6q 6734 16 12).Withdrawal 12).withdrawal CD cord-006870-f5w6fw6q 6734 17 of of IN cord-006870-f5w6fw6q 6734 18 life life NN cord-006870-f5w6fw6q 6734 19 support support NN cord-006870-f5w6fw6q 6734 20 was be VBD cord-006870-f5w6fw6q 6734 21 the the DT cord-006870-f5w6fw6q 6734 22 main main JJ cord-006870-f5w6fw6q 6734 23 reason reason NN cord-006870-f5w6fw6q 6734 24 of of IN cord-006870-f5w6fw6q 6734 25 death death NN cord-006870-f5w6fw6q 6734 26 in in IN cord-006870-f5w6fw6q 6734 27 both both DT cord-006870-f5w6fw6q 6734 28 centers center NNS cord-006870-f5w6fw6q 6734 29 ( ( -LRB- cord-006870-f5w6fw6q 6734 30 total total NN cord-006870-f5w6fw6q 6734 31 of of IN cord-006870-f5w6fw6q 6734 32 107 107 CD cord-006870-f5w6fw6q 6734 33 deaths death NNS cord-006870-f5w6fw6q 6734 34 -71 -71 VBG cord-006870-f5w6fw6q 6734 35 % % NN cord-006870-f5w6fw6q 6734 36 ) ) -RRB- cord-006870-f5w6fw6q 6734 37 , , , cord-006870-f5w6fw6q 6734 38 cardiopulmonary cardiopulmonary JJ cord-006870-f5w6fw6q 6734 39 causes cause NNS cord-006870-f5w6fw6q 6734 40 , , , cord-006870-f5w6fw6q 6734 41 aneurysm aneurysm NN cord-006870-f5w6fw6q 6734 42 rebleeding rebleeding NN cord-006870-f5w6fw6q 6734 43 , , , cord-006870-f5w6fw6q 6734 44 refractory refractory JJ cord-006870-f5w6fw6q 6734 45 intracranial intracranial JJ cord-006870-f5w6fw6q 6734 46 hypertension hypertension NN cord-006870-f5w6fw6q 6734 47 , , , cord-006870-f5w6fw6q 6734 48 and and CC cord-006870-f5w6fw6q 6734 49 other other JJ cord-006870-f5w6fw6q 6734 50 extracranial extracranial JJ cord-006870-f5w6fw6q 6734 51 causes cause NNS cord-006870-f5w6fw6q 6734 52 ) ) -RRB- cord-006870-f5w6fw6q 6734 53 , , , cord-006870-f5w6fw6q 6734 54 represented represent VBD cord-006870-f5w6fw6q 6734 55 less less JJR cord-006870-f5w6fw6q 6734 56 than than IN cord-006870-f5w6fw6q 6734 57 15 15 CD cord-006870-f5w6fw6q 6734 58 % % NN cord-006870-f5w6fw6q 6734 59 . . . cord-006870-f5w6fw6q 6734 60 _SP cord-006870-f5w6fw6q 6735 1 Extensive extensive JJ cord-006870-f5w6fw6q 6735 2 review review NN cord-006870-f5w6fw6q 6735 3 of of IN cord-006870-f5w6fw6q 6735 4 patients patient NNS cord-006870-f5w6fw6q 6735 5 chart chart VBP cord-006870-f5w6fw6q 6735 6 for for IN cord-006870-f5w6fw6q 6735 7 all all PDT cord-006870-f5w6fw6q 6735 8 the the DT cord-006870-f5w6fw6q 6735 9 data data NN cord-006870-f5w6fw6q 6735 10 collection collection NN cord-006870-f5w6fw6q 6735 11 including include VBG cord-006870-f5w6fw6q 6735 12 literature literature NN cord-006870-f5w6fw6q 6735 13 search search NN cord-006870-f5w6fw6q 6735 14 for for IN cord-006870-f5w6fw6q 6735 15 similar similar JJ cord-006870-f5w6fw6q 6735 16 cases case NNS cord-006870-f5w6fw6q 6735 17 if if IN cord-006870-f5w6fw6q 6735 18 reported report VBN cord-006870-f5w6fw6q 6735 19 before before RB cord-006870-f5w6fw6q 6735 20 . . . cord-006870-f5w6fw6q 6736 1 Although although IN cord-006870-f5w6fw6q 6736 2 rare rare JJ cord-006870-f5w6fw6q 6736 3 , , , cord-006870-f5w6fw6q 6736 4 there there EX cord-006870-f5w6fw6q 6736 5 are be VBP cord-006870-f5w6fw6q 6736 6 multiple multiple JJ cord-006870-f5w6fw6q 6736 7 case case NN cord-006870-f5w6fw6q 6736 8 reports report NNS cord-006870-f5w6fw6q 6736 9 and and CC cord-006870-f5w6fw6q 6736 10 series series NN cord-006870-f5w6fw6q 6736 11 of of IN cord-006870-f5w6fw6q 6736 12 NKH NKH NNP cord-006870-f5w6fw6q 6736 13 and and CC cord-006870-f5w6fw6q 6736 14 clinical clinical JJ cord-006870-f5w6fw6q 6736 15 findings finding NNS cord-006870-f5w6fw6q 6736 16 of of IN cord-006870-f5w6fw6q 6736 17 Hemichorea Hemichorea NNP cord-006870-f5w6fw6q 6736 18 - - HYPH cord-006870-f5w6fw6q 6736 19 Hemiballism Hemiballism NNP cord-006870-f5w6fw6q 6736 20 ( ( -LRB- cord-006870-f5w6fw6q 6736 21 HC HC NNP cord-006870-f5w6fw6q 6736 22 - - HYPH cord-006870-f5w6fw6q 6736 23 HB HB NNP cord-006870-f5w6fw6q 6736 24 ) ) -RRB- cord-006870-f5w6fw6q 6736 25 . . . cord-006870-f5w6fw6q 6737 1 There there EX cord-006870-f5w6fw6q 6737 2 are be VBP cord-006870-f5w6fw6q 6737 3 few few JJ cord-006870-f5w6fw6q 6737 4 case case NN cord-006870-f5w6fw6q 6737 5 reports report NNS cord-006870-f5w6fw6q 6737 6 of of IN cord-006870-f5w6fw6q 6737 7 NKH NKH NNP cord-006870-f5w6fw6q 6737 8 with with IN cord-006870-f5w6fw6q 6737 9 unilateral unilateral JJ cord-006870-f5w6fw6q 6737 10 signal signal NN cord-006870-f5w6fw6q 6737 11 changes change NNS cord-006870-f5w6fw6q 6737 12 in in IN cord-006870-f5w6fw6q 6737 13 the the DT cord-006870-f5w6fw6q 6737 14 caudate caudate NN cord-006870-f5w6fw6q 6737 15 and and CC cord-006870-f5w6fw6q 6737 16 putamen putaman NNS cord-006870-f5w6fw6q 6737 17 . . . cord-006870-f5w6fw6q 6738 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6738 2 patient patient NN cord-006870-f5w6fw6q 6738 3 presented present VBN cord-006870-f5w6fw6q 6738 4 with with IN cord-006870-f5w6fw6q 6738 5 acute acute JJ cord-006870-f5w6fw6q 6738 6 right right JJ cord-006870-f5w6fw6q 6738 7 basal basal NN cord-006870-f5w6fw6q 6738 8 ganglia ganglion NNS cord-006870-f5w6fw6q 6738 9 ICH ICH NNP cord-006870-f5w6fw6q 6738 10 . . . cord-006870-f5w6fw6q 6739 1 Despite despite IN cord-006870-f5w6fw6q 6739 2 the the DT cord-006870-f5w6fw6q 6739 3 typical typical JJ cord-006870-f5w6fw6q 6739 4 imaging imaging NN cord-006870-f5w6fw6q 6739 5 findings finding NNS cord-006870-f5w6fw6q 6739 6 of of IN cord-006870-f5w6fw6q 6739 7 NKH NKH NNP cord-006870-f5w6fw6q 6739 8 , , , cord-006870-f5w6fw6q 6739 9 work work NN cord-006870-f5w6fw6q 6739 10 - - HYPH cord-006870-f5w6fw6q 6739 11 up up NN cord-006870-f5w6fw6q 6739 12 and and CC cord-006870-f5w6fw6q 6739 13 management management NN cord-006870-f5w6fw6q 6739 14 of of IN cord-006870-f5w6fw6q 6739 15 ICH ICH NNP cord-006870-f5w6fw6q 6739 16 took take VBD cord-006870-f5w6fw6q 6739 17 precedence precedence NN cord-006870-f5w6fw6q 6739 18 over over IN cord-006870-f5w6fw6q 6739 19 control control NN cord-006870-f5w6fw6q 6739 20 of of IN cord-006870-f5w6fw6q 6739 21 BG BG NNP cord-006870-f5w6fw6q 6739 22 . . . cord-006870-f5w6fw6q 6740 1 MRI MRI NNP cord-006870-f5w6fw6q 6740 2 findings finding NNS cord-006870-f5w6fw6q 6740 3 were be VBD cord-006870-f5w6fw6q 6740 4 different different JJ cord-006870-f5w6fw6q 6740 5 in in IN cord-006870-f5w6fw6q 6740 6 our -PRON- PRP$ cord-006870-f5w6fw6q 6740 7 patient patient NN cord-006870-f5w6fw6q 6740 8 given give VBN cord-006870-f5w6fw6q 6740 9 presence presence NN cord-006870-f5w6fw6q 6740 10 of of IN cord-006870-f5w6fw6q 6740 11 positive positive JJ cord-006870-f5w6fw6q 6740 12 GRE GRE NNP cord-006870-f5w6fw6q 6740 13 and and CC cord-006870-f5w6fw6q 6740 14 DWI DWI NNP cord-006870-f5w6fw6q 6740 15 / / SYM cord-006870-f5w6fw6q 6740 16 ADC ADC NNP cord-006870-f5w6fw6q 6740 17 in in IN cord-006870-f5w6fw6q 6740 18 areas area NNS cord-006870-f5w6fw6q 6740 19 other other JJ cord-006870-f5w6fw6q 6740 20 than than IN cord-006870-f5w6fw6q 6740 21 T1 T1 NNP cord-006870-f5w6fw6q 6740 22 hyperintensity hyperintensity NN cord-006870-f5w6fw6q 6740 23 , , , cord-006870-f5w6fw6q 6740 24 which which WDT cord-006870-f5w6fw6q 6740 25 is be VBZ cord-006870-f5w6fw6q 6740 26 known know VBN cord-006870-f5w6fw6q 6740 27 to to TO cord-006870-f5w6fw6q 6740 28 be be VB cord-006870-f5w6fw6q 6740 29 associated associate VBN cord-006870-f5w6fw6q 6740 30 with with IN cord-006870-f5w6fw6q 6740 31 NKH NKH NNP cord-006870-f5w6fw6q 6740 32 . . . cord-006870-f5w6fw6q 6741 1 We -PRON- PRP cord-006870-f5w6fw6q 6741 2 hypothesize hypothesize VBP cord-006870-f5w6fw6q 6741 3 an an DT cord-006870-f5w6fw6q 6741 4 association association NN cord-006870-f5w6fw6q 6741 5 between between IN cord-006870-f5w6fw6q 6741 6 Ischemia Ischemia NNP cord-006870-f5w6fw6q 6741 7 and and CC cord-006870-f5w6fw6q 6741 8 hemosiderin hemosiderin NNP cord-006870-f5w6fw6q 6741 9 deposition deposition NN cord-006870-f5w6fw6q 6741 10 with with IN cord-006870-f5w6fw6q 6741 11 Hyperglycemia hyperglycemia NN cord-006870-f5w6fw6q 6741 12 . . . cord-006870-f5w6fw6q 6742 1 The the DT cord-006870-f5w6fw6q 6742 2 selective selective JJ cord-006870-f5w6fw6q 6742 3 vulnerability vulnerability NN cord-006870-f5w6fw6q 6742 4 of of IN cord-006870-f5w6fw6q 6742 5 unilateral unilateral JJ cord-006870-f5w6fw6q 6742 6 involvement involvement NN cord-006870-f5w6fw6q 6742 7 of of IN cord-006870-f5w6fw6q 6742 8 basal basal NN cord-006870-f5w6fw6q 6742 9 ganglia ganglion NNS cord-006870-f5w6fw6q 6742 10 and and CC cord-006870-f5w6fw6q 6742 11 caudate caudate NN cord-006870-f5w6fw6q 6742 12 is be VBZ cord-006870-f5w6fw6q 6742 13 unclear unclear JJ cord-006870-f5w6fw6q 6742 14 and and CC cord-006870-f5w6fw6q 6742 15 needs need VBZ cord-006870-f5w6fw6q 6742 16 more more JJR cord-006870-f5w6fw6q 6742 17 research research NN cord-006870-f5w6fw6q 6742 18 . . . cord-006870-f5w6fw6q 6743 1 Identification identification NN cord-006870-f5w6fw6q 6743 2 of of IN cord-006870-f5w6fw6q 6743 3 neuroimaging neuroimage VBG cord-006870-f5w6fw6q 6743 4 findings finding NNS cord-006870-f5w6fw6q 6743 5 in in IN cord-006870-f5w6fw6q 6743 6 NKH NKH NNP cord-006870-f5w6fw6q 6743 7 in in IN cord-006870-f5w6fw6q 6743 8 absence absence NN cord-006870-f5w6fw6q 6743 9 of of IN cord-006870-f5w6fw6q 6743 10 focal focal JJ cord-006870-f5w6fw6q 6743 11 neurological neurological JJ cord-006870-f5w6fw6q 6743 12 deficits deficit NNS cord-006870-f5w6fw6q 6743 13 ( ( -LRB- cord-006870-f5w6fw6q 6743 14 HC HC NNP cord-006870-f5w6fw6q 6743 15 - - HYPH cord-006870-f5w6fw6q 6743 16 HB HB NNP cord-006870-f5w6fw6q 6743 17 ) ) -RRB- cord-006870-f5w6fw6q 6743 18 is be VBZ cord-006870-f5w6fw6q 6743 19 important important JJ cord-006870-f5w6fw6q 6743 20 , , , cord-006870-f5w6fw6q 6743 21 especially especially RB cord-006870-f5w6fw6q 6743 22 for for IN cord-006870-f5w6fw6q 6743 23 a a DT cord-006870-f5w6fw6q 6743 24 first first JJ cord-006870-f5w6fw6q 6743 25 responder responder NN cord-006870-f5w6fw6q 6743 26 . . . cord-006870-f5w6fw6q 6744 1 Early early JJ cord-006870-f5w6fw6q 6744 2 recognition recognition NN cord-006870-f5w6fw6q 6744 3 can can MD cord-006870-f5w6fw6q 6744 4 prevent prevent VB cord-006870-f5w6fw6q 6744 5 ICU ICU NNP cord-006870-f5w6fw6q 6744 6 admission admission NN cord-006870-f5w6fw6q 6744 7 , , , cord-006870-f5w6fw6q 6744 8 provide provide VB cord-006870-f5w6fw6q 6744 9 efficient efficient JJ cord-006870-f5w6fw6q 6744 10 patient patient NN cord-006870-f5w6fw6q 6744 11 care care NN cord-006870-f5w6fw6q 6744 12 and and CC cord-006870-f5w6fw6q 6744 13 allocation allocation NN cord-006870-f5w6fw6q 6744 14 of of IN cord-006870-f5w6fw6q 6744 15 resources resource NNS cord-006870-f5w6fw6q 6744 16 . . . cord-006870-f5w6fw6q 6745 1 Although although IN cord-006870-f5w6fw6q 6745 2 most most JJS cord-006870-f5w6fw6q 6745 3 metabolic metabolic JJ cord-006870-f5w6fw6q 6745 4 diseases disease NNS cord-006870-f5w6fw6q 6745 5 affect affect VBP cord-006870-f5w6fw6q 6745 6 basal basal NN cord-006870-f5w6fw6q 6745 7 ganglia ganglion NNS cord-006870-f5w6fw6q 6745 8 bilaterally bilaterally RB cord-006870-f5w6fw6q 6745 9 ; ; : cord-006870-f5w6fw6q 6745 10 NKH NKH NNP cord-006870-f5w6fw6q 6745 11 is be VBZ cord-006870-f5w6fw6q 6745 12 associated associate VBN cord-006870-f5w6fw6q 6745 13 with with IN cord-006870-f5w6fw6q 6745 14 specific specific JJ cord-006870-f5w6fw6q 6745 15 unilateral unilateral JJ cord-006870-f5w6fw6q 6745 16 neuroimaging neuroimaging NN cord-006870-f5w6fw6q 6745 17 findings finding NNS cord-006870-f5w6fw6q 6745 18 even even RB cord-006870-f5w6fw6q 6745 19 in in IN cord-006870-f5w6fw6q 6745 20 absence absence NN cord-006870-f5w6fw6q 6745 21 of of IN cord-006870-f5w6fw6q 6745 22 movement movement NN cord-006870-f5w6fw6q 6745 23 disorders disorder NNS cord-006870-f5w6fw6q 6745 24 or or CC cord-006870-f5w6fw6q 6745 25 focal focal JJ cord-006870-f5w6fw6q 6745 26 neurological neurological JJ cord-006870-f5w6fw6q 6745 27 deficits deficit NNS cord-006870-f5w6fw6q 6745 28 . . . cord-006870-f5w6fw6q 6745 29 _SP cord-006870-f5w6fw6q 6746 1 A a DT cord-006870-f5w6fw6q 6746 2 32 32 CD cord-006870-f5w6fw6q 6746 3 year year NN cord-006870-f5w6fw6q 6746 4 old old JJ cord-006870-f5w6fw6q 6746 5 male male NN cord-006870-f5w6fw6q 6746 6 with with IN cord-006870-f5w6fw6q 6746 7 a a DT cord-006870-f5w6fw6q 6746 8 history history NN cord-006870-f5w6fw6q 6746 9 of of IN cord-006870-f5w6fw6q 6746 10 seizure seizure NN cord-006870-f5w6fw6q 6746 11 disorder disorder NN cord-006870-f5w6fw6q 6746 12 due due IN cord-006870-f5w6fw6q 6746 13 to to IN cord-006870-f5w6fw6q 6746 14 mesial mesial JJ cord-006870-f5w6fw6q 6746 15 temporal temporal JJ cord-006870-f5w6fw6q 6746 16 lobe lobe NN cord-006870-f5w6fw6q 6746 17 sclerosis sclerosis NN cord-006870-f5w6fw6q 6746 18 , , , cord-006870-f5w6fw6q 6746 19 presented present VBN cord-006870-f5w6fw6q 6746 20 with with IN cord-006870-f5w6fw6q 6746 21 altered altered JJ cord-006870-f5w6fw6q 6746 22 mental mental JJ cord-006870-f5w6fw6q 6746 23 status status NN cord-006870-f5w6fw6q 6746 24 after after IN cord-006870-f5w6fw6q 6746 25 a a DT cord-006870-f5w6fw6q 6746 26 lamotrigine lamotrigine NN cord-006870-f5w6fw6q 6746 27 overdose overdose NN cord-006870-f5w6fw6q 6746 28 . . . cord-006870-f5w6fw6q 6747 1 He -PRON- PRP cord-006870-f5w6fw6q 6747 2 had have VBD cord-006870-f5w6fw6q 6747 3 consumed consume VBN cord-006870-f5w6fw6q 6747 4 9.6 9.6 CD cord-006870-f5w6fw6q 6747 5 gm gm NNP cord-006870-f5w6fw6q 6747 6 of of IN cord-006870-f5w6fw6q 6747 7 the the DT cord-006870-f5w6fw6q 6747 8 drug drug NN cord-006870-f5w6fw6q 6747 9 . . . cord-006870-f5w6fw6q 6748 1 He -PRON- PRP cord-006870-f5w6fw6q 6748 2 was be VBD cord-006870-f5w6fw6q 6748 3 awake awake JJ cord-006870-f5w6fw6q 6748 4 and and CC cord-006870-f5w6fw6q 6748 5 alert alert JJ cord-006870-f5w6fw6q 6748 6 at at IN cord-006870-f5w6fw6q 6748 7 presentation presentation NN cord-006870-f5w6fw6q 6748 8 . . . cord-006870-f5w6fw6q 6749 1 Urine urine NN cord-006870-f5w6fw6q 6749 2 toxicology toxicology NN cord-006870-f5w6fw6q 6749 3 was be VBD cord-006870-f5w6fw6q 6749 4 negative negative JJ cord-006870-f5w6fw6q 6749 5 . . . cord-006870-f5w6fw6q 6750 1 Initial initial JJ cord-006870-f5w6fw6q 6750 2 Creatine Creatine NNP cord-006870-f5w6fw6q 6750 3 Kinase Kinase NNP cord-006870-f5w6fw6q 6750 4 ( ( -LRB- cord-006870-f5w6fw6q 6750 5 CK CK NNP cord-006870-f5w6fw6q 6750 6 ) ) -RRB- cord-006870-f5w6fw6q 6750 7 was be VBD cord-006870-f5w6fw6q 6750 8 1478 1478 CD cord-006870-f5w6fw6q 6750 9 IU IU NNP cord-006870-f5w6fw6q 6750 10 / / SYM cord-006870-f5w6fw6q 6750 11 L L NNP cord-006870-f5w6fw6q 6750 12 and and CC cord-006870-f5w6fw6q 6750 13 peaked peak VBD cord-006870-f5w6fw6q 6750 14 at at IN cord-006870-f5w6fw6q 6750 15 5974 5974 CD cord-006870-f5w6fw6q 6750 16 IU IU NNP cord-006870-f5w6fw6q 6750 17 / / SYM cord-006870-f5w6fw6q 6750 18 L L NNP cord-006870-f5w6fw6q 6750 19 ; ; : cord-006870-f5w6fw6q 6750 20 his -PRON- PRP$ cord-006870-f5w6fw6q 6750 21 creatinine creatinine NN cord-006870-f5w6fw6q 6750 22 was be VBD cord-006870-f5w6fw6q 6750 23 1.3 1.3 CD cord-006870-f5w6fw6q 6750 24 mg/ mg/ NN cord-006870-f5w6fw6q 6751 1 dL. dL. NNP cord-006870-f5w6fw6q 6751 2 Lamotrigine Lamotrigine NNP cord-006870-f5w6fw6q 6751 3 level level NN cord-006870-f5w6fw6q 6751 4 went go VBD cord-006870-f5w6fw6q 6751 5 from from IN cord-006870-f5w6fw6q 6751 6 14 14 CD cord-006870-f5w6fw6q 6751 7 mcg mcg NN cord-006870-f5w6fw6q 6751 8 / / SYM cord-006870-f5w6fw6q 6751 9 ml ml NN cord-006870-f5w6fw6q 6751 10 to to IN cord-006870-f5w6fw6q 6751 11 38.6 38.6 CD cord-006870-f5w6fw6q 6751 12 mcg mcg NN cord-006870-f5w6fw6q 6751 13 / / SYM cord-006870-f5w6fw6q 6751 14 ml ml NN cord-006870-f5w6fw6q 6751 15 after after IN cord-006870-f5w6fw6q 6751 16 18 18 CD cord-006870-f5w6fw6q 6751 17 hours hour NNS cord-006870-f5w6fw6q 6751 18 . . . cord-006870-f5w6fw6q 6752 1 Four four CD cord-006870-f5w6fw6q 6752 2 days day NNS cord-006870-f5w6fw6q 6752 3 after after IN cord-006870-f5w6fw6q 6752 4 admission admission NN cord-006870-f5w6fw6q 6752 5 it -PRON- PRP cord-006870-f5w6fw6q 6752 6 was be VBD cord-006870-f5w6fw6q 6752 7 31 31 CD cord-006870-f5w6fw6q 6752 8 mcg mcg NN cord-006870-f5w6fw6q 6752 9 / / SYM cord-006870-f5w6fw6q 6752 10 ml ml NN cord-006870-f5w6fw6q 6752 11 . . . cord-006870-f5w6fw6q 6753 1 A a DT cord-006870-f5w6fw6q 6753 2 head head NN cord-006870-f5w6fw6q 6753 3 CT CT NNP cord-006870-f5w6fw6q 6753 4 at at IN cord-006870-f5w6fw6q 6753 5 admission admission NN cord-006870-f5w6fw6q 6753 6 was be VBD cord-006870-f5w6fw6q 6753 7 negative negative JJ cord-006870-f5w6fw6q 6753 8 . . . cord-006870-f5w6fw6q 6754 1 Despite despite IN cord-006870-f5w6fw6q 6754 2 initial initial JJ cord-006870-f5w6fw6q 6754 3 alertness alertness NN cord-006870-f5w6fw6q 6754 4 , , , cord-006870-f5w6fw6q 6754 5 he -PRON- PRP cord-006870-f5w6fw6q 6754 6 developed develop VBD cord-006870-f5w6fw6q 6754 7 profound profound JJ cord-006870-f5w6fw6q 6754 8 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6754 9 with with IN cord-006870-f5w6fw6q 6754 10 agitation agitation NN cord-006870-f5w6fw6q 6754 11 and and CC cord-006870-f5w6fw6q 6754 12 rigidity rigidity NN cord-006870-f5w6fw6q 6754 13 , , , cord-006870-f5w6fw6q 6754 14 requiring require VBG cord-006870-f5w6fw6q 6754 15 heavy heavy JJ cord-006870-f5w6fw6q 6754 16 sedation sedation NN cord-006870-f5w6fw6q 6754 17 , , , cord-006870-f5w6fw6q 6754 18 induced induce VBN cord-006870-f5w6fw6q 6754 19 paralysis paralysis NN cord-006870-f5w6fw6q 6754 20 , , , cord-006870-f5w6fw6q 6754 21 and and CC cord-006870-f5w6fw6q 6754 22 intubation intubation NN cord-006870-f5w6fw6q 6754 23 . . . cord-006870-f5w6fw6q 6755 1 This this DT cord-006870-f5w6fw6q 6755 2 in in IN cord-006870-f5w6fw6q 6755 3 turn turn NN cord-006870-f5w6fw6q 6755 4 lead lead VBP cord-006870-f5w6fw6q 6755 5 to to IN cord-006870-f5w6fw6q 6755 6 hemodynamic hemodynamic JJ cord-006870-f5w6fw6q 6755 7 instability instability NN cord-006870-f5w6fw6q 6755 8 , , , cord-006870-f5w6fw6q 6755 9 which which WDT cord-006870-f5w6fw6q 6755 10 along along IN cord-006870-f5w6fw6q 6755 11 with with IN cord-006870-f5w6fw6q 6755 12 persistently persistently RB cord-006870-f5w6fw6q 6755 13 elevated elevate VBN cord-006870-f5w6fw6q 6755 14 lamotrigine lamotrigine NN cord-006870-f5w6fw6q 6755 15 levels level NNS cord-006870-f5w6fw6q 6755 16 , , , cord-006870-f5w6fw6q 6755 17 prompted prompt VBD cord-006870-f5w6fw6q 6755 18 initiation initiation NN cord-006870-f5w6fw6q 6755 19 of of IN cord-006870-f5w6fw6q 6755 20 Continuous Continuous NNP cord-006870-f5w6fw6q 6755 21 Veno Veno NNP cord-006870-f5w6fw6q 6755 22 - - HYPH cord-006870-f5w6fw6q 6755 23 Venous Venous NNP cord-006870-f5w6fw6q 6755 24 Hemodia Hemodia NNP cord-006870-f5w6fw6q 6755 25 - - HYPH cord-006870-f5w6fw6q 6755 26 Filtration Filtration NNP cord-006870-f5w6fw6q 6755 27 ( ( -LRB- cord-006870-f5w6fw6q 6755 28 CVVHDF CVVHDF NNP cord-006870-f5w6fw6q 6755 29 ) ) -RRB- cord-006870-f5w6fw6q 6755 30 on on IN cord-006870-f5w6fw6q 6755 31 hospital hospital NN cord-006870-f5w6fw6q 6755 32 day day NN cord-006870-f5w6fw6q 6755 33 5 5 CD cord-006870-f5w6fw6q 6755 34 . . . cord-006870-f5w6fw6q 6756 1 The the DT cord-006870-f5w6fw6q 6756 2 lamotrigine lamotrigine NN cord-006870-f5w6fw6q 6756 3 level level NN cord-006870-f5w6fw6q 6756 4 declined decline VBD cord-006870-f5w6fw6q 6756 5 to to IN cord-006870-f5w6fw6q 6756 6 13.3 13.3 CD cord-006870-f5w6fw6q 6756 7 mcg mcg NN cord-006870-f5w6fw6q 6756 8 / / SYM cord-006870-f5w6fw6q 6756 9 mL ml NN cord-006870-f5w6fw6q 6756 10 within within IN cord-006870-f5w6fw6q 6756 11 24 24 CD cord-006870-f5w6fw6q 6756 12 hours hour NNS cord-006870-f5w6fw6q 6756 13 , , , cord-006870-f5w6fw6q 6756 14 the the DT cord-006870-f5w6fw6q 6756 15 encephalopathy encephalopathy NN cord-006870-f5w6fw6q 6756 16 and and CC cord-006870-f5w6fw6q 6756 17 rigidity rigidity NN cord-006870-f5w6fw6q 6756 18 resolved resolve VBD cord-006870-f5w6fw6q 6756 19 , , , cord-006870-f5w6fw6q 6756 20 and and CC cord-006870-f5w6fw6q 6756 21 he -PRON- PRP cord-006870-f5w6fw6q 6756 22 was be VBD cord-006870-f5w6fw6q 6756 23 extubated extubate VBN cord-006870-f5w6fw6q 6756 24 . . . cord-006870-f5w6fw6q 6757 1 To to IN cord-006870-f5w6fw6q 6757 2 our -PRON- PRP$ cord-006870-f5w6fw6q 6757 3 knowledge knowledge NN cord-006870-f5w6fw6q 6757 4 , , , cord-006870-f5w6fw6q 6757 5 this this DT cord-006870-f5w6fw6q 6757 6 is be VBZ cord-006870-f5w6fw6q 6757 7 the the DT cord-006870-f5w6fw6q 6757 8 first first JJ cord-006870-f5w6fw6q 6757 9 reported report VBN cord-006870-f5w6fw6q 6757 10 case case NN cord-006870-f5w6fw6q 6757 11 of of IN cord-006870-f5w6fw6q 6757 12 lamotrigine lamotrigine NN cord-006870-f5w6fw6q 6757 13 toxicity toxicity NN cord-006870-f5w6fw6q 6757 14 managed manage VBN cord-006870-f5w6fw6q 6757 15 with with IN cord-006870-f5w6fw6q 6757 16 CVVHDF CVVHDF NNP cord-006870-f5w6fw6q 6757 17 . . . cord-006870-f5w6fw6q 6758 1 Overdoses overdose NNS cord-006870-f5w6fw6q 6758 2 up up IN cord-006870-f5w6fw6q 6758 3 to to TO cord-006870-f5w6fw6q 6758 4 15 15 CD cord-006870-f5w6fw6q 6758 5 g g NN cord-006870-f5w6fw6q 6758 6 have have VBP cord-006870-f5w6fw6q 6758 7 been be VBN cord-006870-f5w6fw6q 6758 8 reported report VBN cord-006870-f5w6fw6q 6758 9 and and CC cord-006870-f5w6fw6q 6758 10 can can MD cord-006870-f5w6fw6q 6758 11 even even RB cord-006870-f5w6fw6q 6758 12 result result VB cord-006870-f5w6fw6q 6758 13 in in IN cord-006870-f5w6fw6q 6758 14 death death NN cord-006870-f5w6fw6q 6758 15 . . . cord-006870-f5w6fw6q 6759 1 While while IN cord-006870-f5w6fw6q 6759 2 cleared clear VBN cord-006870-f5w6fw6q 6759 3 hepatically hepatically RB cord-006870-f5w6fw6q 6759 4 , , , cord-006870-f5w6fw6q 6759 5 the the DT cord-006870-f5w6fw6q 6759 6 half half JJ cord-006870-f5w6fw6q 6759 7 - - HYPH cord-006870-f5w6fw6q 6759 8 life life NN cord-006870-f5w6fw6q 6759 9 of of IN cord-006870-f5w6fw6q 6759 10 lamotrigine lamotrigine NN cord-006870-f5w6fw6q 6759 11 is be VBZ cord-006870-f5w6fw6q 6759 12 approximately approximately RB cord-006870-f5w6fw6q 6759 13 twice twice RB cord-006870-f5w6fw6q 6759 14 as as RB cord-006870-f5w6fw6q 6759 15 long long RB cord-006870-f5w6fw6q 6759 16 when when WRB cord-006870-f5w6fw6q 6759 17 patients patient NNS cord-006870-f5w6fw6q 6759 18 have have VBP cord-006870-f5w6fw6q 6759 19 chronic chronic JJ cord-006870-f5w6fw6q 6759 20 renal renal JJ cord-006870-f5w6fw6q 6759 21 failure failure NN cord-006870-f5w6fw6q 6759 22 . . . cord-006870-f5w6fw6q 6760 1 In in IN cord-006870-f5w6fw6q 6760 2 a a DT cord-006870-f5w6fw6q 6760 3 small small JJ cord-006870-f5w6fw6q 6760 4 series series NN cord-006870-f5w6fw6q 6760 5 of of IN cord-006870-f5w6fw6q 6760 6 6 6 CD cord-006870-f5w6fw6q 6760 7 patients patient NNS cord-006870-f5w6fw6q 6760 8 with with IN cord-006870-f5w6fw6q 6760 9 renal renal JJ cord-006870-f5w6fw6q 6760 10 failure failure NN cord-006870-f5w6fw6q 6760 11 , , , cord-006870-f5w6fw6q 6760 12 approximately approximately RB cord-006870-f5w6fw6q 6760 13 20 20 CD cord-006870-f5w6fw6q 6760 14 % % NN cord-006870-f5w6fw6q 6760 15 of of IN cord-006870-f5w6fw6q 6760 16 lamotrigine lamotrigine NN cord-006870-f5w6fw6q 6760 17 was be VBD cord-006870-f5w6fw6q 6760 18 reported report VBN cord-006870-f5w6fw6q 6760 19 to to TO cord-006870-f5w6fw6q 6760 20 be be VB cord-006870-f5w6fw6q 6760 21 removed remove VBN cord-006870-f5w6fw6q 6760 22 by by IN cord-006870-f5w6fw6q 6760 23 hemodialysis hemodialysis NN cord-006870-f5w6fw6q 6760 24 . . . cord-006870-f5w6fw6q 6761 1 We -PRON- PRP cord-006870-f5w6fw6q 6761 2 applied apply VBD cord-006870-f5w6fw6q 6761 3 this this DT cord-006870-f5w6fw6q 6761 4 principal principal NN cord-006870-f5w6fw6q 6761 5 to to IN cord-006870-f5w6fw6q 6761 6 our -PRON- PRP$ cord-006870-f5w6fw6q 6761 7 patient patient NN cord-006870-f5w6fw6q 6761 8 . . . cord-006870-f5w6fw6q 6762 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6762 2 experience experience NN cord-006870-f5w6fw6q 6762 3 suggests suggest VBZ cord-006870-f5w6fw6q 6762 4 that that IN cord-006870-f5w6fw6q 6762 5 augmenting augment VBG cord-006870-f5w6fw6q 6762 6 drug drug NN cord-006870-f5w6fw6q 6762 7 clearance clearance NN cord-006870-f5w6fw6q 6762 8 with with IN cord-006870-f5w6fw6q 6762 9 dialysis dialysis NN cord-006870-f5w6fw6q 6762 10 may may MD cord-006870-f5w6fw6q 6762 11 help help VB cord-006870-f5w6fw6q 6762 12 reduce reduce VB cord-006870-f5w6fw6q 6762 13 the the DT cord-006870-f5w6fw6q 6762 14 time time NN cord-006870-f5w6fw6q 6762 15 on on IN cord-006870-f5w6fw6q 6762 16 mechanical mechanical JJ cord-006870-f5w6fw6q 6762 17 ventilation ventilation NN cord-006870-f5w6fw6q 6762 18 , , , cord-006870-f5w6fw6q 6762 19 need need VBP cord-006870-f5w6fw6q 6762 20 for for IN cord-006870-f5w6fw6q 6762 21 higher high JJR cord-006870-f5w6fw6q 6762 22 doses dose NNS cord-006870-f5w6fw6q 6762 23 of of IN cord-006870-f5w6fw6q 6762 24 sedatives sedative NNS cord-006870-f5w6fw6q 6762 25 , , , cord-006870-f5w6fw6q 6762 26 and and CC cord-006870-f5w6fw6q 6762 27 improve improve VB cord-006870-f5w6fw6q 6762 28 time time NN cord-006870-f5w6fw6q 6762 29 to to TO cord-006870-f5w6fw6q 6762 30 discharge discharge VB cord-006870-f5w6fw6q 6762 31 . . . cord-006870-f5w6fw6q 6763 1 CVVHDF CVVHDF NNP cord-006870-f5w6fw6q 6763 2 should should MD cord-006870-f5w6fw6q 6763 3 be be VB cord-006870-f5w6fw6q 6763 4 considered consider VBN cord-006870-f5w6fw6q 6763 5 a a DT cord-006870-f5w6fw6q 6763 6 supplemental supplemental JJ cord-006870-f5w6fw6q 6763 7 treatment treatment NN cord-006870-f5w6fw6q 6763 8 option option NN cord-006870-f5w6fw6q 6763 9 for for IN cord-006870-f5w6fw6q 6763 10 lamotrigine lamotrigine NN cord-006870-f5w6fw6q 6763 11 toxicity toxicity NN cord-006870-f5w6fw6q 6763 12 . . . cord-006870-f5w6fw6q 6763 13 _SP cord-006870-f5w6fw6q 6764 1 Traumatic traumatic JJ cord-006870-f5w6fw6q 6764 2 brain brain NN cord-006870-f5w6fw6q 6764 3 injury injury NN cord-006870-f5w6fw6q 6765 1 ( ( -LRB- cord-006870-f5w6fw6q 6765 2 TBI TBI NNP cord-006870-f5w6fw6q 6765 3 ) ) -RRB- cord-006870-f5w6fw6q 6765 4 complicated complicate VBN cord-006870-f5w6fw6q 6765 5 by by IN cord-006870-f5w6fw6q 6765 6 percutaneous percutaneous JJ cord-006870-f5w6fw6q 6765 7 coronary coronary NN cord-006870-f5w6fw6q 6765 8 intervention intervention NN cord-006870-f5w6fw6q 6765 9 ( ( -LRB- cord-006870-f5w6fw6q 6765 10 PCI PCI NNP cord-006870-f5w6fw6q 6765 11 ) ) -RRB- cord-006870-f5w6fw6q 6765 12 remains remain VBZ cord-006870-f5w6fw6q 6765 13 a a DT cord-006870-f5w6fw6q 6765 14 significant significant JJ cord-006870-f5w6fw6q 6765 15 clinical clinical JJ cord-006870-f5w6fw6q 6765 16 dilemma dilemma NN cord-006870-f5w6fw6q 6765 17 . . . cord-006870-f5w6fw6q 6766 1 Dual dual JJ cord-006870-f5w6fw6q 6766 2 anti anti JJ cord-006870-f5w6fw6q 6766 3 - - JJ cord-006870-f5w6fw6q 6766 4 platelet platelet JJ cord-006870-f5w6fw6q 6766 5 therapy therapy NN cord-006870-f5w6fw6q 6766 6 ( ( -LRB- cord-006870-f5w6fw6q 6766 7 DAPT DAPT NNP cord-006870-f5w6fw6q 6766 8 ) ) -RRB- cord-006870-f5w6fw6q 6766 9 is be VBZ cord-006870-f5w6fw6q 6766 10 standard standard JJ cord-006870-f5w6fw6q 6766 11 after after IN cord-006870-f5w6fw6q 6766 12 PCI PCI NNP cord-006870-f5w6fw6q 6766 13 , , , cord-006870-f5w6fw6q 6766 14 but but CC cord-006870-f5w6fw6q 6766 15 may may MD cord-006870-f5w6fw6q 6766 16 contribute contribute VB cord-006870-f5w6fw6q 6766 17 to to IN cord-006870-f5w6fw6q 6766 18 progression progression NN cord-006870-f5w6fw6q 6766 19 of of IN cord-006870-f5w6fw6q 6766 20 TBI TBI NNP cord-006870-f5w6fw6q 6766 21 . . . cord-006870-f5w6fw6q 6767 1 Novel novel NN cord-006870-f5w6fw6q 6768 1 antiplatelet antiplatelet JJ cord-006870-f5w6fw6q 6768 2 drugs drug NNS cord-006870-f5w6fw6q 6768 3 with with IN cord-006870-f5w6fw6q 6768 4 ultra ultra JJ cord-006870-f5w6fw6q 6768 5 - - JJ cord-006870-f5w6fw6q 6768 6 short short JJ cord-006870-f5w6fw6q 6768 7 half half NN cord-006870-f5w6fw6q 6768 8 - - HYPH cord-006870-f5w6fw6q 6768 9 lives life NNS cord-006870-f5w6fw6q 6768 10 , , , cord-006870-f5w6fw6q 6768 11 such such JJ cord-006870-f5w6fw6q 6768 12 as as IN cord-006870-f5w6fw6q 6768 13 the the DT cord-006870-f5w6fw6q 6768 14 P2Y12-adenosine P2Y12-adenosine NNP cord-006870-f5w6fw6q 6768 15 receptor receptor NN cord-006870-f5w6fw6q 6768 16 antagonist antagonist NN cord-006870-f5w6fw6q 6768 17 , , , cord-006870-f5w6fw6q 6768 18 cangrelor cangrelor NNP cord-006870-f5w6fw6q 6768 19 , , , cord-006870-f5w6fw6q 6768 20 may may MD cord-006870-f5w6fw6q 6768 21 provide provide VB cord-006870-f5w6fw6q 6768 22 added add VBN cord-006870-f5w6fw6q 6768 23 clinical clinical JJ cord-006870-f5w6fw6q 6768 24 flexibility flexibility NN cord-006870-f5w6fw6q 6768 25 in in IN cord-006870-f5w6fw6q 6768 26 avoiding avoid VBG cord-006870-f5w6fw6q 6768 27 TBI TBI NNP cord-006870-f5w6fw6q 6768 28 - - HYPH cord-006870-f5w6fw6q 6768 29 associated associate VBN cord-006870-f5w6fw6q 6768 30 hematoma hematoma NN cord-006870-f5w6fw6q 6768 31 progression progression NN cord-006870-f5w6fw6q 6768 32 , , , cord-006870-f5w6fw6q 6768 33 particularly particularly RB cord-006870-f5w6fw6q 6768 34 in in IN cord-006870-f5w6fw6q 6768 35 the the DT cord-006870-f5w6fw6q 6768 36 absence absence NN cord-006870-f5w6fw6q 6768 37 of of IN cord-006870-f5w6fw6q 6768 38 reversibility reversibility NN cord-006870-f5w6fw6q 6768 39 options option NNS cord-006870-f5w6fw6q 6768 40 . . . cord-006870-f5w6fw6q 6769 1 Case case NN cord-006870-f5w6fw6q 6769 2 report report NN cord-006870-f5w6fw6q 6769 3 . . . cord-006870-f5w6fw6q 6770 1 We -PRON- PRP cord-006870-f5w6fw6q 6770 2 report report VBP cord-006870-f5w6fw6q 6770 3 a a DT cord-006870-f5w6fw6q 6770 4 53 53 CD cord-006870-f5w6fw6q 6770 5 year year NN cord-006870-f5w6fw6q 6770 6 - - HYPH cord-006870-f5w6fw6q 6770 7 old old JJ cord-006870-f5w6fw6q 6770 8 female female NN cord-006870-f5w6fw6q 6770 9 who who WP cord-006870-f5w6fw6q 6770 10 presented present VBD cord-006870-f5w6fw6q 6770 11 to to IN cord-006870-f5w6fw6q 6770 12 the the DT cord-006870-f5w6fw6q 6770 13 ED ED NNP cord-006870-f5w6fw6q 6770 14 after after IN cord-006870-f5w6fw6q 6770 15 a a DT cord-006870-f5w6fw6q 6770 16 syncopal syncopal JJ cord-006870-f5w6fw6q 6770 17 episode episode NN cord-006870-f5w6fw6q 6770 18 with with IN cord-006870-f5w6fw6q 6770 19 a a DT cord-006870-f5w6fw6q 6770 20 fall fall NN cord-006870-f5w6fw6q 6770 21 down down IN cord-006870-f5w6fw6q 6770 22 a a DT cord-006870-f5w6fw6q 6770 23 flight flight NN cord-006870-f5w6fw6q 6770 24 of of IN cord-006870-f5w6fw6q 6770 25 stairs stair NNS cord-006870-f5w6fw6q 6770 26 . . . cord-006870-f5w6fw6q 6771 1 An an DT cord-006870-f5w6fw6q 6771 2 EKG ekg NN cord-006870-f5w6fw6q 6771 3 was be VBD cord-006870-f5w6fw6q 6771 4 obtained obtain VBN cord-006870-f5w6fw6q 6771 5 demonstrating demonstrate VBG cord-006870-f5w6fw6q 6771 6 inferior inferior JJ cord-006870-f5w6fw6q 6771 7 wall wall NN cord-006870-f5w6fw6q 6771 8 STEMI STEMI NNP cord-006870-f5w6fw6q 6771 9 . . . cord-006870-f5w6fw6q 6772 1 Signs sign NNS cord-006870-f5w6fw6q 6772 2 of of IN cord-006870-f5w6fw6q 6772 3 head head NN cord-006870-f5w6fw6q 6772 4 trauma trauma NN cord-006870-f5w6fw6q 6772 5 included include VBD cord-006870-f5w6fw6q 6772 6 facial facial JJ cord-006870-f5w6fw6q 6772 7 and and CC cord-006870-f5w6fw6q 6772 8 scalp scalp NN cord-006870-f5w6fw6q 6772 9 contusions contusion NNS cord-006870-f5w6fw6q 6772 10 , , , cord-006870-f5w6fw6q 6772 11 and and CC cord-006870-f5w6fw6q 6772 12 bloody bloody JJ cord-006870-f5w6fw6q 6772 13 otorrhea otorrhea NN cord-006870-f5w6fw6q 6772 14 . . . cord-006870-f5w6fw6q 6773 1 Initial initial JJ cord-006870-f5w6fw6q 6773 2 GCS GCS NNP cord-006870-f5w6fw6q 6773 3 was be VBD cord-006870-f5w6fw6q 6773 4 14 14 CD cord-006870-f5w6fw6q 6773 5 . . . cord-006870-f5w6fw6q 6774 1 A a DT cord-006870-f5w6fw6q 6774 2 non non JJ cord-006870-f5w6fw6q 6774 3 - - JJ cord-006870-f5w6fw6q 6774 4 contrast contrast JJ cord-006870-f5w6fw6q 6774 5 head head NN cord-006870-f5w6fw6q 6774 6 CT CT NNP cord-006870-f5w6fw6q 6774 7 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6774 8 tSAH tsah NN cord-006870-f5w6fw6q 6774 9 and and CC cord-006870-f5w6fw6q 6774 10 contusions contusion NNS cord-006870-f5w6fw6q 6774 11 of of IN cord-006870-f5w6fw6q 6774 12 bilateral bilateral JJ cord-006870-f5w6fw6q 6774 13 frontal frontal JJ cord-006870-f5w6fw6q 6774 14 lobes lobe NNS cord-006870-f5w6fw6q 6774 15 and and CC cord-006870-f5w6fw6q 6774 16 left leave VBN cord-006870-f5w6fw6q 6774 17 temporal temporal JJ cord-006870-f5w6fw6q 6774 18 lobe lobe NN cord-006870-f5w6fw6q 6774 19 , , , cord-006870-f5w6fw6q 6774 20 and and CC cord-006870-f5w6fw6q 6774 21 a a DT cord-006870-f5w6fw6q 6774 22 non non JJ cord-006870-f5w6fw6q 6774 23 - - JJ cord-006870-f5w6fw6q 6774 24 displaced displaced JJ cord-006870-f5w6fw6q 6774 25 fracture fracture NN cord-006870-f5w6fw6q 6774 26 of of IN cord-006870-f5w6fw6q 6774 27 the the DT cord-006870-f5w6fw6q 6774 28 left left JJ cord-006870-f5w6fw6q 6774 29 temporal temporal JJ cord-006870-f5w6fw6q 6774 30 bone bone NN cord-006870-f5w6fw6q 6774 31 . . . cord-006870-f5w6fw6q 6775 1 Neurosurgery Neurosurgery NNP cord-006870-f5w6fw6q 6775 2 , , , cord-006870-f5w6fw6q 6775 3 Interventional Interventional NNP cord-006870-f5w6fw6q 6775 4 Cardiology Cardiology NNP cord-006870-f5w6fw6q 6775 5 and and CC cord-006870-f5w6fw6q 6775 6 Critical Critical NNP cord-006870-f5w6fw6q 6775 7 Care Care NNP cord-006870-f5w6fw6q 6775 8 were be VBD cord-006870-f5w6fw6q 6775 9 consulted consult VBN cord-006870-f5w6fw6q 6775 10 . . . cord-006870-f5w6fw6q 6776 1 The the DT cord-006870-f5w6fw6q 6776 2 patient patient NN cord-006870-f5w6fw6q 6776 3 developed develop VBD cord-006870-f5w6fw6q 6776 4 signs sign NNS cord-006870-f5w6fw6q 6776 5 of of IN cord-006870-f5w6fw6q 6776 6 cardiogenic cardiogenic JJ cord-006870-f5w6fw6q 6776 7 shock shock NN cord-006870-f5w6fw6q 6776 8 related relate VBN cord-006870-f5w6fw6q 6776 9 to to IN cord-006870-f5w6fw6q 6776 10 STEMI STEMI NNP cord-006870-f5w6fw6q 6776 11 and and CC cord-006870-f5w6fw6q 6776 12 was be VBD cord-006870-f5w6fw6q 6776 13 taken take VBN cord-006870-f5w6fw6q 6776 14 emergently emergently RB cord-006870-f5w6fw6q 6776 15 to to IN cord-006870-f5w6fw6q 6776 16 cath cath NN cord-006870-f5w6fw6q 6776 17 lab lab NN cord-006870-f5w6fw6q 6776 18 . . . cord-006870-f5w6fw6q 6777 1 Successful successful JJ cord-006870-f5w6fw6q 6777 2 revascularization revascularization NN cord-006870-f5w6fw6q 6777 3 of of IN cord-006870-f5w6fw6q 6777 4 proximal proximal JJ cord-006870-f5w6fw6q 6777 5 RCA RCA NNP cord-006870-f5w6fw6q 6777 6 occlusion occlusion NN cord-006870-f5w6fw6q 6777 7 was be VBD cord-006870-f5w6fw6q 6777 8 achieved achieve VBN cord-006870-f5w6fw6q 6777 9 . . . cord-006870-f5w6fw6q 6778 1 Heparin Heparin NNP cord-006870-f5w6fw6q 6778 2 was be VBD cord-006870-f5w6fw6q 6778 3 given give VBN cord-006870-f5w6fw6q 6778 4 per per IN cord-006870-f5w6fw6q 6778 5 protocol protocol NN cord-006870-f5w6fw6q 6778 6 , , , cord-006870-f5w6fw6q 6778 7 and and CC cord-006870-f5w6fw6q 6778 8 aspirin aspirin NN cord-006870-f5w6fw6q 6778 9 and and CC cord-006870-f5w6fw6q 6778 10 cangrelor cangrelor NN cord-006870-f5w6fw6q 6778 11 administered administer VBN cord-006870-f5w6fw6q 6778 12 post post JJ cord-006870-f5w6fw6q 6778 13 - - JJ cord-006870-f5w6fw6q 6778 14 PCI pci JJ cord-006870-f5w6fw6q 6778 15 . . . cord-006870-f5w6fw6q 6779 1 Cath cath NN cord-006870-f5w6fw6q 6779 2 lab lab NN cord-006870-f5w6fw6q 6779 3 was be VBD cord-006870-f5w6fw6q 6779 4 complicated complicate VBN cord-006870-f5w6fw6q 6779 5 by by IN cord-006870-f5w6fw6q 6779 6 tonic tonic JJ cord-006870-f5w6fw6q 6779 7 - - HYPH cord-006870-f5w6fw6q 6779 8 clonic clonic JJ cord-006870-f5w6fw6q 6779 9 seizures seizure NNS cord-006870-f5w6fw6q 6779 10 requiring require VBG cord-006870-f5w6fw6q 6779 11 intubation intubation NN cord-006870-f5w6fw6q 6779 12 . . . cord-006870-f5w6fw6q 6780 1 Repeat repeat VB cord-006870-f5w6fw6q 6780 2 head head NN cord-006870-f5w6fw6q 6780 3 CT CT NNP cord-006870-f5w6fw6q 6780 4 demonstrated demonstrate VBD cord-006870-f5w6fw6q 6780 5 blossoming blossom VBG cord-006870-f5w6fw6q 6780 6 of of IN cord-006870-f5w6fw6q 6780 7 bifrontal bifrontal JJ cord-006870-f5w6fw6q 6780 8 contusions contusion NNS cord-006870-f5w6fw6q 6780 9 , , , cord-006870-f5w6fw6q 6780 10 trace trace NN cord-006870-f5w6fw6q 6780 11 subdural subdural JJ cord-006870-f5w6fw6q 6780 12 hematoma hematoma NN cord-006870-f5w6fw6q 6780 13 development development NN cord-006870-f5w6fw6q 6780 14 and and CC cord-006870-f5w6fw6q 6780 15 increased increase VBN cord-006870-f5w6fw6q 6780 16 tSAH tsah JJ cord-006870-f5w6fw6q 6780 17 conspicuity conspicuity NN cord-006870-f5w6fw6q 6780 18 . . . cord-006870-f5w6fw6q 6781 1 DAPT dapt JJ cord-006870-f5w6fw6q 6781 2 infusion infusion NN cord-006870-f5w6fw6q 6781 3 was be VBD cord-006870-f5w6fw6q 6781 4 continued continue VBN cord-006870-f5w6fw6q 6781 5 , , , cord-006870-f5w6fw6q 6781 6 and and CC cord-006870-f5w6fw6q 6781 7 subsequent subsequent JJ cord-006870-f5w6fw6q 6781 8 imaging imaging NN cord-006870-f5w6fw6q 6781 9 was be VBD cord-006870-f5w6fw6q 6781 10 stable stable JJ cord-006870-f5w6fw6q 6781 11 , , , cord-006870-f5w6fw6q 6781 12 allowing allow VBG cord-006870-f5w6fw6q 6781 13 transition transition NN cord-006870-f5w6fw6q 6781 14 to to IN cord-006870-f5w6fw6q 6781 15 ASA ASA NNP cord-006870-f5w6fw6q 6781 16 and and CC cord-006870-f5w6fw6q 6781 17 clopidogrel clopidogrel NN cord-006870-f5w6fw6q 6781 18 . . . cord-006870-f5w6fw6q 6782 1 She -PRON- PRP cord-006870-f5w6fw6q 6782 2 survived survive VBD cord-006870-f5w6fw6q 6782 3 with with IN cord-006870-f5w6fw6q 6782 4 only only JJ cord-006870-f5w6fw6q 6782 5 minor minor JJ cord-006870-f5w6fw6q 6782 6 disability disability NN cord-006870-f5w6fw6q 6782 7 . . . cord-006870-f5w6fw6q 6783 1 Newer new JJR cord-006870-f5w6fw6q 6783 2 generation generation NN cord-006870-f5w6fw6q 6783 3 P2Y12 P2Y12 NNP cord-006870-f5w6fw6q 6783 4 inhibitors inhibitor NNS cord-006870-f5w6fw6q 6783 5 can can MD cord-006870-f5w6fw6q 6783 6 be be VB cord-006870-f5w6fw6q 6783 7 administered administer VBN cord-006870-f5w6fw6q 6783 8 intravenously intravenously RB cord-006870-f5w6fw6q 6783 9 with with IN cord-006870-f5w6fw6q 6783 10 reliable reliable JJ cord-006870-f5w6fw6q 6783 11 platelet platelet NN cord-006870-f5w6fw6q 6783 12 inhibition inhibition NN cord-006870-f5w6fw6q 6783 13 similar similar JJ cord-006870-f5w6fw6q 6783 14 to to IN cord-006870-f5w6fw6q 6783 15 older old JJR cord-006870-f5w6fw6q 6783 16 P2Y12 P2Y12 NNP cord-006870-f5w6fw6q 6783 17 receptor receptor NN cord-006870-f5w6fw6q 6783 18 inhibitors inhibitor NNS cord-006870-f5w6fw6q 6783 19 . . . cord-006870-f5w6fw6q 6784 1 With with IN cord-006870-f5w6fw6q 6784 2 rapid rapid JJ cord-006870-f5w6fw6q 6784 3 reversibility reversibility NN cord-006870-f5w6fw6q 6784 4 upon upon IN cord-006870-f5w6fw6q 6784 5 discontinuation discontinuation NN cord-006870-f5w6fw6q 6784 6 , , , cord-006870-f5w6fw6q 6784 7 their -PRON- PRP$ cord-006870-f5w6fw6q 6784 8 utilization utilization NN cord-006870-f5w6fw6q 6784 9 should should MD cord-006870-f5w6fw6q 6784 10 be be VB cord-006870-f5w6fw6q 6784 11 considered consider VBN cord-006870-f5w6fw6q 6784 12 any any DT cord-006870-f5w6fw6q 6784 13 time time NN cord-006870-f5w6fw6q 6784 14 PCI pci NN cord-006870-f5w6fw6q 6784 15 complicates complicate VBZ cord-006870-f5w6fw6q 6784 16 TBI TBI NNP cord-006870-f5w6fw6q 6784 17 . . . cord-006870-f5w6fw6q 6784 18 _SP cord-006870-f5w6fw6q 6785 1 Cerebral cerebral JJ cord-006870-f5w6fw6q 6785 2 air air NN cord-006870-f5w6fw6q 6785 3 embolism embolism NN cord-006870-f5w6fw6q 6785 4 ( ( -LRB- cord-006870-f5w6fw6q 6785 5 CAE CAE NNP cord-006870-f5w6fw6q 6785 6 ) ) -RRB- cord-006870-f5w6fw6q 6785 7 is be VBZ cord-006870-f5w6fw6q 6785 8 a a DT cord-006870-f5w6fw6q 6785 9 rare rare JJ cord-006870-f5w6fw6q 6785 10 but but CC cord-006870-f5w6fw6q 6785 11 potentially potentially RB cord-006870-f5w6fw6q 6785 12 fatal fatal JJ cord-006870-f5w6fw6q 6785 13 entity entity NN cord-006870-f5w6fw6q 6785 14 with with IN cord-006870-f5w6fw6q 6785 15 high high JJ cord-006870-f5w6fw6q 6785 16 morbidity morbidity NN cord-006870-f5w6fw6q 6785 17 and and CC cord-006870-f5w6fw6q 6785 18 mortality mortality NN cord-006870-f5w6fw6q 6785 19 , , , cord-006870-f5w6fw6q 6785 20 commonly commonly RB cord-006870-f5w6fw6q 6785 21 seen see VBN cord-006870-f5w6fw6q 6785 22 secondary secondary JJ cord-006870-f5w6fw6q 6785 23 to to IN cord-006870-f5w6fw6q 6785 24 iatrogenic iatrogenic JJ cord-006870-f5w6fw6q 6785 25 causes cause NNS cord-006870-f5w6fw6q 6785 26 like like IN cord-006870-f5w6fw6q 6785 27 neurosurgical neurosurgical JJ cord-006870-f5w6fw6q 6785 28 procedures procedure NNS cord-006870-f5w6fw6q 6785 29 , , , cord-006870-f5w6fw6q 6785 30 Vascular vascular JJ cord-006870-f5w6fw6q 6785 31 surgeries surgery NNS cord-006870-f5w6fw6q 6785 32 , , , cord-006870-f5w6fw6q 6785 33 etc etc FW cord-006870-f5w6fw6q 6785 34 . . . cord-006870-f5w6fw6q 6786 1 as as IN cord-006870-f5w6fw6q 6786 2 also also RB cord-006870-f5w6fw6q 6786 3 deep deep JJ cord-006870-f5w6fw6q 6786 4 sea sea NN cord-006870-f5w6fw6q 6786 5 diving diving NN cord-006870-f5w6fw6q 6786 6 . . . cord-006870-f5w6fw6q 6787 1 CAE CAE NNP cord-006870-f5w6fw6q 6787 2 after after IN cord-006870-f5w6fw6q 6787 3 esophagogastroduodenoscopy esophagogastroduodenoscopy NNP cord-006870-f5w6fw6q 6787 4 ( ( -LRB- cord-006870-f5w6fw6q 6787 5 EGD EGD NNP cord-006870-f5w6fw6q 6787 6 ) ) -RRB- cord-006870-f5w6fw6q 6787 7 is be VBZ cord-006870-f5w6fw6q 6787 8 extremely extremely RB cord-006870-f5w6fw6q 6787 9 uncommon uncommon JJ cord-006870-f5w6fw6q 6787 10 . . . cord-006870-f5w6fw6q 6788 1 We -PRON- PRP cord-006870-f5w6fw6q 6788 2 present present VBP cord-006870-f5w6fw6q 6788 3 a a DT cord-006870-f5w6fw6q 6788 4 rare rare JJ cord-006870-f5w6fw6q 6788 5 case case NN cord-006870-f5w6fw6q 6788 6 of of IN cord-006870-f5w6fw6q 6788 7 CAE CAE NNP cord-006870-f5w6fw6q 6788 8 post post NN cord-006870-f5w6fw6q 6788 9 EGD EGD NNP cord-006870-f5w6fw6q 6788 10 resulting result VBG cord-006870-f5w6fw6q 6788 11 in in IN cord-006870-f5w6fw6q 6788 12 diffuse diffuse JJ cord-006870-f5w6fw6q 6788 13 cortical cortical JJ cord-006870-f5w6fw6q 6788 14 infarction infarction NN cord-006870-f5w6fw6q 6788 15 . . . cord-006870-f5w6fw6q 6789 1 An an DT cord-006870-f5w6fw6q 6789 2 80 80 CD cord-006870-f5w6fw6q 6789 3 year year NN cord-006870-f5w6fw6q 6789 4 old old JJ cord-006870-f5w6fw6q 6789 5 man man NN cord-006870-f5w6fw6q 6789 6 underwent undergo VBD cord-006870-f5w6fw6q 6789 7 an an DT cord-006870-f5w6fw6q 6789 8 elective elective JJ cord-006870-f5w6fw6q 6789 9 ( ( -LRB- cord-006870-f5w6fw6q 6789 10 EGD EGD NNP cord-006870-f5w6fw6q 6789 11 ) ) -RRB- cord-006870-f5w6fw6q 6789 12 for for IN cord-006870-f5w6fw6q 6789 13 esophageal esophageal JJ cord-006870-f5w6fw6q 6789 14 stricture stricture NN cord-006870-f5w6fw6q 6789 15 with with IN cord-006870-f5w6fw6q 6789 16 biopsy biopsy NN cord-006870-f5w6fw6q 6789 17 and and CC cord-006870-f5w6fw6q 6789 18 balloon balloon NN cord-006870-f5w6fw6q 6789 19 dilatation dilatation NN cord-006870-f5w6fw6q 6789 20 . . . cord-006870-f5w6fw6q 6790 1 Patient Patient NNP cord-006870-f5w6fw6q 6790 2 did do VBD cord-006870-f5w6fw6q 6790 3 not not RB cord-006870-f5w6fw6q 6790 4 wake wake VB cord-006870-f5w6fw6q 6790 5 up up RP cord-006870-f5w6fw6q 6790 6 after after IN cord-006870-f5w6fw6q 6790 7 procedure procedure NN cord-006870-f5w6fw6q 6790 8 . . . cord-006870-f5w6fw6q 6791 1 On on IN cord-006870-f5w6fw6q 6791 2 initial initial JJ cord-006870-f5w6fw6q 6791 3 exam exam NN cord-006870-f5w6fw6q 6791 4 , , , cord-006870-f5w6fw6q 6791 5 patient patient JJ cord-006870-f5w6fw6q 6791 6 was be VBD cord-006870-f5w6fw6q 6791 7 comatose comatose JJ cord-006870-f5w6fw6q 6791 8 , , , cord-006870-f5w6fw6q 6791 9 Glasgow Glasgow NNP cord-006870-f5w6fw6q 6791 10 Coma Coma NNP cord-006870-f5w6fw6q 6791 11 Scale Scale NNP cord-006870-f5w6fw6q 6791 12 4 4 CD cord-006870-f5w6fw6q 6791 13 T t NN cord-006870-f5w6fw6q 6791 14 with with IN cord-006870-f5w6fw6q 6791 15 decerebrate decerebrate JJ cord-006870-f5w6fw6q 6791 16 posturing posturing NN cord-006870-f5w6fw6q 6791 17 . . . cord-006870-f5w6fw6q 6792 1 Computed compute VBN cord-006870-f5w6fw6q 6792 2 tomography tomography NN cord-006870-f5w6fw6q 6792 3 ( ( -LRB- cord-006870-f5w6fw6q 6792 4 CT CT NNP cord-006870-f5w6fw6q 6792 5 ) ) -RRB- cord-006870-f5w6fw6q 6792 6 revealed reveal VBD cord-006870-f5w6fw6q 6792 7 multiple multiple JJ cord-006870-f5w6fw6q 6792 8 foci focus NNS cord-006870-f5w6fw6q 6792 9 of of IN cord-006870-f5w6fw6q 6792 10 cerebral cerebral JJ cord-006870-f5w6fw6q 6792 11 air air NN cord-006870-f5w6fw6q 6792 12 embolism embolism NN cord-006870-f5w6fw6q 6792 13 . . . cord-006870-f5w6fw6q 6793 1 CT CT NNP cord-006870-f5w6fw6q 6793 2 Angiogram Angiogram NNP cord-006870-f5w6fw6q 6793 3 of of IN cord-006870-f5w6fw6q 6793 4 the the DT cord-006870-f5w6fw6q 6793 5 brain brain NN cord-006870-f5w6fw6q 6793 6 was be VBD cord-006870-f5w6fw6q 6793 7 negative negative JJ cord-006870-f5w6fw6q 6793 8 . . . cord-006870-f5w6fw6q 6794 1 Diffusion Diffusion NNP cord-006870-f5w6fw6q 6794 2 Weighted Weighted NNP cord-006870-f5w6fw6q 6794 3 Imaging Imaging NNP cord-006870-f5w6fw6q 6794 4 and and CC cord-006870-f5w6fw6q 6794 5 Apparent Apparent NNP cord-006870-f5w6fw6q 6794 6 Diffusion Diffusion NNP cord-006870-f5w6fw6q 6794 7 Coefficient Coefficient NNP cord-006870-f5w6fw6q 6794 8 imaging imaging NN cord-006870-f5w6fw6q 6794 9 sequences sequence NNS cord-006870-f5w6fw6q 6794 10 in in IN cord-006870-f5w6fw6q 6794 11 magnetic magnetic JJ cord-006870-f5w6fw6q 6794 12 resonance resonance NN cord-006870-f5w6fw6q 6794 13 imaging imaging NN cord-006870-f5w6fw6q 6794 14 ( ( -LRB- cord-006870-f5w6fw6q 6794 15 MRI MRI NNP cord-006870-f5w6fw6q 6794 16 ) ) -RRB- cord-006870-f5w6fw6q 6794 17 showed show VBD cord-006870-f5w6fw6q 6794 18 diffuse diffuse JJ cord-006870-f5w6fw6q 6794 19 , , , cord-006870-f5w6fw6q 6794 20 global global JJ cord-006870-f5w6fw6q 6794 21 bi bi JJ cord-006870-f5w6fw6q 6794 22 - - JJ cord-006870-f5w6fw6q 6794 23 hemispheric hemispheric JJ cord-006870-f5w6fw6q 6794 24 cortical cortical JJ cord-006870-f5w6fw6q 6794 25 infarction infarction NN cord-006870-f5w6fw6q 6794 26 . . . cord-006870-f5w6fw6q 6795 1 CT CT NNP cord-006870-f5w6fw6q 6795 2 chest chest NN cord-006870-f5w6fw6q 6795 3 showed show VBD cord-006870-f5w6fw6q 6795 4 pneumomediastinum pneumomediastinum NNP cord-006870-f5w6fw6q 6795 5 . . . cord-006870-f5w6fw6q 6796 1 Only only RB cord-006870-f5w6fw6q 6796 2 21 21 CD cord-006870-f5w6fw6q 6796 3 cases case NNS cord-006870-f5w6fw6q 6796 4 of of IN cord-006870-f5w6fw6q 6796 5 CAE CAE NNP cord-006870-f5w6fw6q 6796 6 from from IN cord-006870-f5w6fw6q 6796 7 EGD EGD NNP cord-006870-f5w6fw6q 6796 8 have have VBP cord-006870-f5w6fw6q 6796 9 been be VBN cord-006870-f5w6fw6q 6796 10 reported report VBN cord-006870-f5w6fw6q 6796 11 in in IN cord-006870-f5w6fw6q 6796 12 literature literature NN cord-006870-f5w6fw6q 6796 13 prior prior RB cord-006870-f5w6fw6q 6796 14 to to IN cord-006870-f5w6fw6q 6796 15 this this DT cord-006870-f5w6fw6q 6796 16 case case NN cord-006870-f5w6fw6q 6796 17 . . . cord-006870-f5w6fw6q 6797 1 5 5 CD cord-006870-f5w6fw6q 6797 2 received receive VBD cord-006870-f5w6fw6q 6797 3 Hyperbaric Hyperbaric NNP cord-006870-f5w6fw6q 6797 4 Oxygen Oxygen NNP cord-006870-f5w6fw6q 6797 5 therapy(HBO therapy(hbo NN cord-006870-f5w6fw6q 6797 6 ) ) -RRB- cord-006870-f5w6fw6q 6797 7 . . . cord-006870-f5w6fw6q 6798 1 12 12 CD cord-006870-f5w6fw6q 6798 2 patients patient NNS cord-006870-f5w6fw6q 6798 3 had have VBD cord-006870-f5w6fw6q 6798 4 a a DT cord-006870-f5w6fw6q 6798 5 documented document VBN cord-006870-f5w6fw6q 6798 6 Patent patent NN cord-006870-f5w6fw6q 6798 7 Foramen Foramen NNP cord-006870-f5w6fw6q 6798 8 Ovale Ovale NNP cord-006870-f5w6fw6q 6798 9 ( ( -LRB- cord-006870-f5w6fw6q 6798 10 PFO PFO NNP cord-006870-f5w6fw6q 6798 11 ) ) -RRB- cord-006870-f5w6fw6q 6798 12 or or CC cord-006870-f5w6fw6q 6798 13 some some DT cord-006870-f5w6fw6q 6798 14 form form NN cord-006870-f5w6fw6q 6798 15 of of IN cord-006870-f5w6fw6q 6798 16 Arteriovenous Arteriovenous NNP cord-006870-f5w6fw6q 6798 17 ( ( -LRB- cord-006870-f5w6fw6q 6798 18 AV av NN cord-006870-f5w6fw6q 6798 19 ) ) -RRB- cord-006870-f5w6fw6q 6798 20 shunt shunt NN cord-006870-f5w6fw6q 6798 21 . . . cord-006870-f5w6fw6q 6799 1 Presence presence NN cord-006870-f5w6fw6q 6799 2 of of IN cord-006870-f5w6fw6q 6799 3 AV AV NNP cord-006870-f5w6fw6q 6799 4 shunts/ shunts/ CD cord-006870-f5w6fw6q 6799 5 PFO PFO NNP cord-006870-f5w6fw6q 6799 6 , , , cord-006870-f5w6fw6q 6799 7 therapeutic therapeutic JJ cord-006870-f5w6fw6q 6799 8 endoscopic endoscopic JJ cord-006870-f5w6fw6q 6799 9 procedures procedure NNS cord-006870-f5w6fw6q 6799 10 providing provide VBG cord-006870-f5w6fw6q 6799 11 vascular vascular JJ cord-006870-f5w6fw6q 6799 12 communication communication NN cord-006870-f5w6fw6q 6799 13 as as RB cord-006870-f5w6fw6q 6799 14 well well RB cord-006870-f5w6fw6q 6799 15 as as IN cord-006870-f5w6fw6q 6799 16 providing provide VBG cord-006870-f5w6fw6q 6799 17 pressure pressure NN cord-006870-f5w6fw6q 6799 18 gradient gradient NN cord-006870-f5w6fw6q 6799 19 are be VBP cord-006870-f5w6fw6q 6799 20 all all DT cord-006870-f5w6fw6q 6799 21 factors factor NNS cord-006870-f5w6fw6q 6799 22 facilitating facilitate VBG cord-006870-f5w6fw6q 6799 23 air air NN cord-006870-f5w6fw6q 6799 24 embolism embolism NN cord-006870-f5w6fw6q 6799 25 associated associate VBN cord-006870-f5w6fw6q 6799 26 with with IN cord-006870-f5w6fw6q 6799 27 EGD EGD NNP cord-006870-f5w6fw6q 6799 28 . . . cord-006870-f5w6fw6q 6800 1 HBO HBO NNP cord-006870-f5w6fw6q 6800 2 therapy therapy NN cord-006870-f5w6fw6q 6800 3 has have VBZ cord-006870-f5w6fw6q 6800 4 been be VBN cord-006870-f5w6fw6q 6800 5 shown show VBN cord-006870-f5w6fw6q 6800 6 to to TO cord-006870-f5w6fw6q 6800 7 improve improve VB cord-006870-f5w6fw6q 6800 8 outcomes outcome NNS cord-006870-f5w6fw6q 6800 9 in in IN cord-006870-f5w6fw6q 6800 10 CAE CAE NNP cord-006870-f5w6fw6q 6800 11 patients patient NNS cord-006870-f5w6fw6q 6800 12 , , , cord-006870-f5w6fw6q 6800 13 initiating initiate VBG cord-006870-f5w6fw6q 6800 14 therapy therapy NN cord-006870-f5w6fw6q 6800 15 > > XX cord-006870-f5w6fw6q 6800 16 6 6 CD cord-006870-f5w6fw6q 6800 17 hours hour NNS cord-006870-f5w6fw6q 6800 18 after after IN cord-006870-f5w6fw6q 6800 19 insult insult NN cord-006870-f5w6fw6q 6800 20 and and CC cord-006870-f5w6fw6q 6800 21 early early JJ cord-006870-f5w6fw6q 6800 22 and and CC cord-006870-f5w6fw6q 6800 23 significant significant JJ cord-006870-f5w6fw6q 6800 24 ischemic ischemic JJ cord-006870-f5w6fw6q 6800 25 changes change NNS cord-006870-f5w6fw6q 6800 26 seen see VBN cord-006870-f5w6fw6q 6800 27 on on IN cord-006870-f5w6fw6q 6801 1 CT/ ct/ IN cord-006870-f5w6fw6q 6801 2 MRI MRI NNP cord-006870-f5w6fw6q 6802 1 prior prior RB cord-006870-f5w6fw6q 6802 2 to to IN cord-006870-f5w6fw6q 6802 3 starting start VBG cord-006870-f5w6fw6q 6802 4 therapy therapy NN cord-006870-f5w6fw6q 6802 5 were be VBD cord-006870-f5w6fw6q 6802 6 strong strong JJ cord-006870-f5w6fw6q 6802 7 predictors predictor NNS cord-006870-f5w6fw6q 6802 8 of of IN cord-006870-f5w6fw6q 6802 9 poor poor JJ cord-006870-f5w6fw6q 6802 10 outcomes outcome NNS cord-006870-f5w6fw6q 6802 11 . . . cord-006870-f5w6fw6q 6803 1 Our -PRON- PRP$ cord-006870-f5w6fw6q 6803 2 patient patient NN cord-006870-f5w6fw6q 6803 3 did do VBD cord-006870-f5w6fw6q 6803 4 not not RB cord-006870-f5w6fw6q 6803 5 have have VB cord-006870-f5w6fw6q 6803 6 a a DT cord-006870-f5w6fw6q 6803 7 documented document VBN cord-006870-f5w6fw6q 6803 8 Echocardiogram Echocardiogram NNP cord-006870-f5w6fw6q 6803 9 with with IN cord-006870-f5w6fw6q 6803 10 a a DT cord-006870-f5w6fw6q 6803 11 shunt shunt NN cord-006870-f5w6fw6q 6803 12 study study NN cord-006870-f5w6fw6q 6803 13 prior prior RB cord-006870-f5w6fw6q 6803 14 to to IN cord-006870-f5w6fw6q 6803 15 the the DT cord-006870-f5w6fw6q 6803 16 EGD EGD NNP cord-006870-f5w6fw6q 6803 17 . . . cord-006870-f5w6fw6q 6804 1 CAE CAE NNP cord-006870-f5w6fw6q 6804 2 after after IN cord-006870-f5w6fw6q 6804 3 EGD EGD NNP cord-006870-f5w6fw6q 6804 4 causing cause VBG cord-006870-f5w6fw6q 6804 5 global global JJ cord-006870-f5w6fw6q 6804 6 cerebral cerebral JJ cord-006870-f5w6fw6q 6804 7 bi bi JJ cord-006870-f5w6fw6q 6804 8 - - JJ cord-006870-f5w6fw6q 6804 9 hemispheric hemispheric JJ cord-006870-f5w6fw6q 6804 10 ischemia ischemia NN cord-006870-f5w6fw6q 6804 11 as as IN cord-006870-f5w6fw6q 6804 12 seen see VBN cord-006870-f5w6fw6q 6804 13 in in IN cord-006870-f5w6fw6q 6804 14 our -PRON- PRP$ cord-006870-f5w6fw6q 6804 15 case case NN cord-006870-f5w6fw6q 6804 16 is be VBZ cord-006870-f5w6fw6q 6804 17 extremely extremely RB cord-006870-f5w6fw6q 6804 18 rare rare JJ cord-006870-f5w6fw6q 6804 19 . . . cord-006870-f5w6fw6q 6805 1 HBO HBO NNP cord-006870-f5w6fw6q 6805 2 has have VBZ cord-006870-f5w6fw6q 6805 3 been be VBN cord-006870-f5w6fw6q 6805 4 shown show VBN cord-006870-f5w6fw6q 6805 5 to to TO cord-006870-f5w6fw6q 6805 6 improve improve VB cord-006870-f5w6fw6q 6805 7 outcomes outcome NNS cord-006870-f5w6fw6q 6805 8 . . . cord-006870-f5w6fw6q 6806 1 Time time NN cord-006870-f5w6fw6q 6806 2 to to IN cord-006870-f5w6fw6q 6806 3 treatment treatment NN cord-006870-f5w6fw6q 6806 4 > > XX cord-006870-f5w6fw6q 6807 1 6hours 6hours CD cord-006870-f5w6fw6q 6807 2 and and CC cord-006870-f5w6fw6q 6807 3 early early JJ cord-006870-f5w6fw6q 6807 4 CT/ ct/ NN cord-006870-f5w6fw6q 6807 5 MRI MRI NNP cord-006870-f5w6fw6q 6807 6 changes change NNS cord-006870-f5w6fw6q 6807 7 suggest suggest VBP cord-006870-f5w6fw6q 6807 8 poor poor JJ cord-006870-f5w6fw6q 6807 9 outcomes outcome NNS cord-006870-f5w6fw6q 6807 10 . . . cord-006870-f5w6fw6q 6808 1 Studies study NNS cord-006870-f5w6fw6q 6808 2 do do VBP cord-006870-f5w6fw6q 6808 3 not not RB cord-006870-f5w6fw6q 6808 4 recommend recommend VB cord-006870-f5w6fw6q 6808 5 benefit benefit NN cord-006870-f5w6fw6q 6808 6 of of IN cord-006870-f5w6fw6q 6808 7 screening screening NN cord-006870-f5w6fw6q 6808 8 for for IN cord-006870-f5w6fw6q 6808 9 PFO PFO NNP cord-006870-f5w6fw6q 6808 10 or or CC cord-006870-f5w6fw6q 6808 11 AV av NN cord-006870-f5w6fw6q 6808 12 shunts shunt NNS cord-006870-f5w6fw6q 6808 13 prior prior RB cord-006870-f5w6fw6q 6808 14 to to IN cord-006870-f5w6fw6q 6808 15 every every DT cord-006870-f5w6fw6q 6808 16 EGD EGD NNP cord-006870-f5w6fw6q 6808 17 . . .