id author title date pages extension mime words sentences flesch summary cache txt cord-027036-lvcxrmih Shaw, Ken The impact of diabetes on COVID‐19 infection 2020-06-09 .txt text/plain 2055 97 42 For example, studies are described reporting defects of cell-mediated immunity and diminished lymphocyte transformation response in people with poorly-controlled diabetes, while impaired leucocyte function, the first line of defence against secondary bacterial infection, can be demonstrated from observation of reduced phagocytic activity with increasing levels of blood glucose. These early reports of COVID-19 infection included observations of 52 critically ill adult patients with coronavirus pneumonia admitted to the ICU at the Wuhan Jin Yin-tan hospital, where diabetes was found in twice the number of individuals who died compared to those who survived (22% vs 10%). 5 This outcome has since been replicated on a wider scale from 552 hospitals across China 6 where, in a total of 1099 patients with established COVID-19 infection, diabetes was present in 7.4% of cases overall, but recorded in a significantly greater proportion of those with severe compared to non-severe disease (16.2% vs 5.7%). ./cache/cord-027036-lvcxrmih.txt ./txt/cord-027036-lvcxrmih.txt