id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269856-6h3j89wn	Paolo Fadini, Gian	Newly-diagnosed diabetes and admission hyperglycemia predict COVID-19 severity by aggravating respiratory deterioration	2020-08-15		.txt	text/plain	3940	201	40	Abstract Aims We investigated whether pre-existing diabetes, newly-diagnosed diabetes, and admission hyperglycemia were associated with COVID-19 severity independently from confounders. Higher glucose level at admission was associated with COVID-19 severity, with a stronger association among patients without as compared to those with pre-existing diabetes (interaction p<0.001). In the present study, we investigated the role of pre-existing diabetes, newly-diagnosed diabetes, and admission glucose levels on the outcome of patients hospitalized for COVID-19. In unadjusted analysis, presence of diabetes (including pre-existing and newly-diagnosed) compared to its absence was associated with a higher incidence of the primary outcome (37.4% vs 20.3%; RR 1.85; 95% C.I. 1.33-2.57; p<0.001; Figure 1A ). In this study, we found that newly-detected diabetes and admission hyperglycemia were more strongly associated with COVID-19 severity outcome than pre-existing diabetes. The association between hyperglycemia and COVID-19 severity was significantly stronger for patients with newly-diagnosed diabetes than for those with pre-existing diabetes.	./cache/cord-269856-6h3j89wn.txt	./txt/cord-269856-6h3j89wn.txt