id author title date pages extension mime words sentences flesch summary cache txt cord-314500-89ovdnxl Dunachie, Susanna The double burden of diabetes and global infection in low and middle-income countries 2018-12-04 .txt text/plain 5810 301 43 Diabetes increases susceptibility to infection and worsens outcomes for some of the world's major infectious diseases such as tuberculosis, melioidosis and dengue, but the relationship between diabetes and many neglected tropical diseases is yet to be accurately characterised. A greater understanding of the impact of diabetes on risks and outcomes for infections causing significant diseases in LMIC is essential in order to develop vaccines and therapies for the growing number of people with diabetes at risk of infection, and to prioritise research agendas, public health interventions and policy. In a metaanalysis of five case-control studies of acute dengue, diabetes was associated with an increased risk of a severe clinical presentation of dengue compared with either asymptomatic infection or non-severe acute dengue, 43 although given the limited data, the authors emphasised this was only suggestive of a link. ./cache/cord-314500-89ovdnxl.txt ./txt/cord-314500-89ovdnxl.txt