id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-350182-s10nong7	Milionis, Charalampos	A brief analysis and hypotheses about the risk of COVID-19 for people with type 1 and type 2 diabetes mellitus	2020-07-20		.txt	text/plain	2733	164	42	Coronavirus disease 2019 (COVID-19) is a respiratory infection which is caused by a novel virus belonging to the Coronaviridae family [1] and is officially named SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2). The existence of diabetes is strongly associated with an increased risk of developing severe COVID-19 in case of infection with SARS-CoV-2 [24, 25] . The present article supports that heightened inflammatory processes constitute the main pathophysiologic factor for the severity of COVID-19 among patients with diabetes mellitus, whilst impairments in immune response and diabetic comorbidities contribute to the aggravated pathogenesis. Yet it remains unclear whether the innate immune response is vitally impaired in both types of diabetes mellitus and whether hyperglycaemia favours the initial virulence of SARS-CoV-2. Furthermore, patients with diabetes mellitus may present dysfunctional type IV (delayed) hypersensitivity reaction and abnormal complement activation [35] which may hinder the immune response. Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection?	./cache/cord-350182-s10nong7.txt	./txt/cord-350182-s10nong7.txt