id	sid	tid	token	lemma	pos
cord-353633-a4pu6rlu	1	1	key	key	NN
cord-353633-a4pu6rlu	1	2	:	:	:
cord-353633-a4pu6rlu	2	1	cord-353633-a4pu6rlu	cord-353633-a4pu6rlu	NNP
cord-353633-a4pu6rlu	2	2	authors	author	NNS
cord-353633-a4pu6rlu	2	3	:	:	:
cord-353633-a4pu6rlu	3	1	Perakakis	Perakakis	NNP
cord-353633-a4pu6rlu	3	2	,	,	,
cord-353633-a4pu6rlu	3	3	Nikolaos	Nikolaos	NNP
cord-353633-a4pu6rlu	3	4	;	;	:
cord-353633-a4pu6rlu	3	5	Stefanakis	Stefanakis	NNP
cord-353633-a4pu6rlu	3	6	,	,	,
cord-353633-a4pu6rlu	3	7	Konstantinos	Konstantinos	NNP
cord-353633-a4pu6rlu	3	8	;	;	:
cord-353633-a4pu6rlu	3	9	Mantzoros	Mantzoros	NNP
cord-353633-a4pu6rlu	3	10	,	,	,
cord-353633-a4pu6rlu	3	11	Christos	Christos	NNP
cord-353633-a4pu6rlu	3	12	S.	S.	NNP
cord-353633-a4pu6rlu	3	13	title	title	NN
cord-353633-a4pu6rlu	3	14	:	:	:
cord-353633-a4pu6rlu	4	1	The	the	DT
cord-353633-a4pu6rlu	4	2	role	role	NN
cord-353633-a4pu6rlu	4	3	of	of	IN
cord-353633-a4pu6rlu	4	4	omics	omic	NNS
cord-353633-a4pu6rlu	4	5	in	in	IN
cord-353633-a4pu6rlu	4	6	the	the	DT
cord-353633-a4pu6rlu	4	7	pathophysiology	pathophysiology	NN
cord-353633-a4pu6rlu	4	8	,	,	,
cord-353633-a4pu6rlu	4	9	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	4	10	and	and	CC
cord-353633-a4pu6rlu	4	11	treatment	treatment	NN
cord-353633-a4pu6rlu	4	12	of	of	IN
cord-353633-a4pu6rlu	4	13	non	non	JJ
cord-353633-a4pu6rlu	4	14	-	-	JJ
cord-353633-a4pu6rlu	4	15	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	4	16	fatty	fatty	JJ
cord-353633-a4pu6rlu	4	17	liver	liver	NN
cord-353633-a4pu6rlu	4	18	disease	disease	NN
cord-353633-a4pu6rlu	4	19	date	date	NN
cord-353633-a4pu6rlu	4	20	:	:	:
cord-353633-a4pu6rlu	4	21	2020	2020	CD
cord-353633-a4pu6rlu	4	22	-	-	HYPH
cord-353633-a4pu6rlu	4	23	07	07	CD
cord-353633-a4pu6rlu	4	24	-	-	HYPH
cord-353633-a4pu6rlu	4	25	23	23	CD
cord-353633-a4pu6rlu	4	26	journal	journal	NN
cord-353633-a4pu6rlu	4	27	:	:	:
cord-353633-a4pu6rlu	5	1	Metabolism	metabolism	NN
cord-353633-a4pu6rlu	5	2	DOI	DOI	NNP
cord-353633-a4pu6rlu	5	3	:	:	:
cord-353633-a4pu6rlu	5	4	10.1016/	10.1016/	CD
cord-353633-a4pu6rlu	6	1	j.metabol.2020.154320	j.metabol.2020.154320	CD
cord-353633-a4pu6rlu	7	1	sha	sha	NNP
cord-353633-a4pu6rlu	7	2	:	:	:
cord-353633-a4pu6rlu	8	1	acfae0f0394b23a3707e0b6c166c1d39463fa9ef	acfae0f0394b23a3707e0b6c166c1d39463fa9ef	NNP
cord-353633-a4pu6rlu	8	2	doc_id	doc_id	CD
cord-353633-a4pu6rlu	8	3	:	:	:
cord-353633-a4pu6rlu	8	4	353633	353633	CD
cord-353633-a4pu6rlu	8	5	cord_uid	cord_uid	NNS
cord-353633-a4pu6rlu	8	6	:	:	:
cord-353633-a4pu6rlu	9	1	a4pu6rlu	a4pu6rlu	LS
cord-353633-a4pu6rlu	9	2	Non	non	JJ
cord-353633-a4pu6rlu	9	3	-	-	JJ
cord-353633-a4pu6rlu	9	4	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	9	5	fatty	fatty	JJ
cord-353633-a4pu6rlu	9	6	liver	liver	NN
cord-353633-a4pu6rlu	9	7	disease	disease	NN
cord-353633-a4pu6rlu	9	8	(	(	-LRB-
cord-353633-a4pu6rlu	9	9	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	9	10	)	)	-RRB-
cord-353633-a4pu6rlu	9	11	is	be	VBZ
cord-353633-a4pu6rlu	9	12	a	a	DT
cord-353633-a4pu6rlu	9	13	multifaceted	multifaceted	JJ
cord-353633-a4pu6rlu	9	14	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	9	15	disorder	disorder	NN
cord-353633-a4pu6rlu	9	16	,	,	,
cord-353633-a4pu6rlu	9	17	whose	whose	WP$
cord-353633-a4pu6rlu	9	18	spectrum	spectrum	NN
cord-353633-a4pu6rlu	9	19	covers	cover	VBZ
cord-353633-a4pu6rlu	9	20	clinical	clinical	JJ
cord-353633-a4pu6rlu	9	21	,	,	,
cord-353633-a4pu6rlu	9	22	histological	histological	JJ
cord-353633-a4pu6rlu	9	23	and	and	CC
cord-353633-a4pu6rlu	9	24	pathophysiological	pathophysiological	JJ
cord-353633-a4pu6rlu	9	25	developments	development	NNS
cord-353633-a4pu6rlu	9	26	ranging	range	VBG
cord-353633-a4pu6rlu	9	27	from	from	IN
cord-353633-a4pu6rlu	9	28	simple	simple	JJ
cord-353633-a4pu6rlu	9	29	steatosis	steatosis	NN
cord-353633-a4pu6rlu	9	30	to	to	IN
cord-353633-a4pu6rlu	9	31	non	non	JJ
cord-353633-a4pu6rlu	9	32	-	-	JJ
cord-353633-a4pu6rlu	9	33	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	9	34	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	9	35	(	(	-LRB-
cord-353633-a4pu6rlu	9	36	NASH	NASH	NNP
cord-353633-a4pu6rlu	9	37	)	)	-RRB-
cord-353633-a4pu6rlu	9	38	and	and	CC
cord-353633-a4pu6rlu	9	39	liver	liver	NN
cord-353633-a4pu6rlu	9	40	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	9	41	,	,	,
cord-353633-a4pu6rlu	9	42	potentially	potentially	RB
cord-353633-a4pu6rlu	9	43	evolving	evolve	VBG
cord-353633-a4pu6rlu	9	44	into	into	IN
cord-353633-a4pu6rlu	9	45	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	9	46	,	,	,
cord-353633-a4pu6rlu	9	47	hepatocellular	hepatocellular	JJ
cord-353633-a4pu6rlu	9	48	carcinoma	carcinoma	NN
cord-353633-a4pu6rlu	9	49	and	and	CC
cord-353633-a4pu6rlu	9	50	liver	liver	NN
cord-353633-a4pu6rlu	9	51	failure	failure	NN
cord-353633-a4pu6rlu	9	52	.	.	.
cord-353633-a4pu6rlu	10	1	Liver	liver	NN
cord-353633-a4pu6rlu	10	2	biopsy	biopsy	NN
cord-353633-a4pu6rlu	10	3	remains	remain	VBZ
cord-353633-a4pu6rlu	10	4	the	the	DT
cord-353633-a4pu6rlu	10	5	gold	gold	NN
cord-353633-a4pu6rlu	10	6	standard	standard	NN
cord-353633-a4pu6rlu	10	7	for	for	IN
cord-353633-a4pu6rlu	10	8	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	10	9	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	10	10	,	,	,
cord-353633-a4pu6rlu	10	11	while	while	IN
cord-353633-a4pu6rlu	10	12	there	there	EX
cord-353633-a4pu6rlu	10	13	are	be	VBP
cord-353633-a4pu6rlu	10	14	no	no	DT
cord-353633-a4pu6rlu	10	15	specific	specific	JJ
cord-353633-a4pu6rlu	10	16	treatments	treatment	NNS
cord-353633-a4pu6rlu	10	17	.	.	.
cord-353633-a4pu6rlu	11	1	An	an	DT
cord-353633-a4pu6rlu	11	2	ever	ever	RB
cord-353633-a4pu6rlu	11	3	-	-	HYPH
cord-353633-a4pu6rlu	11	4	increasing	increase	VBG
cord-353633-a4pu6rlu	11	5	number	number	NN
cord-353633-a4pu6rlu	11	6	of	of	IN
cord-353633-a4pu6rlu	11	7	high	high	JJ
cord-353633-a4pu6rlu	11	8	-	-	HYPH
cord-353633-a4pu6rlu	11	9	throughput	throughput	NN
cord-353633-a4pu6rlu	11	10	Omics	Omics	NNP
cord-353633-a4pu6rlu	11	11	investigations	investigation	NNS
cord-353633-a4pu6rlu	11	12	on	on	IN
cord-353633-a4pu6rlu	11	13	the	the	DT
cord-353633-a4pu6rlu	11	14	molecular	molecular	JJ
cord-353633-a4pu6rlu	11	15	pathobiology	pathobiology	NN
cord-353633-a4pu6rlu	11	16	of	of	IN
cord-353633-a4pu6rlu	11	17	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	11	18	at	at	IN
cord-353633-a4pu6rlu	11	19	the	the	DT
cord-353633-a4pu6rlu	11	20	cellular	cellular	NN
cord-353633-a4pu6rlu	11	21	,	,	,
cord-353633-a4pu6rlu	11	22	tissue	tissue	NN
cord-353633-a4pu6rlu	11	23	and	and	CC
cord-353633-a4pu6rlu	11	24	system	system	NN
cord-353633-a4pu6rlu	11	25	levels	level	NNS
cord-353633-a4pu6rlu	11	26	produce	produce	VBP
cord-353633-a4pu6rlu	11	27	comprehensive	comprehensive	JJ
cord-353633-a4pu6rlu	11	28	biochemical	biochemical	JJ
cord-353633-a4pu6rlu	11	29	patient	patient	NN
cord-353633-a4pu6rlu	11	30	snapshots	snapshot	NNS
cord-353633-a4pu6rlu	11	31	.	.	.
cord-353633-a4pu6rlu	12	1	In	in	IN
cord-353633-a4pu6rlu	12	2	the	the	DT
cord-353633-a4pu6rlu	12	3	clinical	clinical	JJ
cord-353633-a4pu6rlu	12	4	setting	setting	NN
cord-353633-a4pu6rlu	12	5	,	,	,
cord-353633-a4pu6rlu	12	6	these	these	DT
cord-353633-a4pu6rlu	12	7	applications	application	NNS
cord-353633-a4pu6rlu	12	8	are	be	VBP
cord-353633-a4pu6rlu	12	9	considerably	considerably	RB
cord-353633-a4pu6rlu	12	10	enhancing	enhance	VBG
cord-353633-a4pu6rlu	12	11	our	-PRON-	PRP$
cord-353633-a4pu6rlu	12	12	efforts	effort	NNS
cord-353633-a4pu6rlu	12	13	toward	toward	IN
cord-353633-a4pu6rlu	12	14	obtaining	obtain	VBG
cord-353633-a4pu6rlu	12	15	a	a	DT
cord-353633-a4pu6rlu	12	16	holistic	holistic	JJ
cord-353633-a4pu6rlu	12	17	insight	insight	NN
cord-353633-a4pu6rlu	12	18	on	on	IN
cord-353633-a4pu6rlu	12	19	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	12	20	pathophysiology	pathophysiology	NN
cord-353633-a4pu6rlu	12	21	.	.	.
cord-353633-a4pu6rlu	13	1	Omics	omic	NNS
cord-353633-a4pu6rlu	13	2	are	be	VBP
cord-353633-a4pu6rlu	13	3	also	also	RB
cord-353633-a4pu6rlu	13	4	generating	generate	VBG
cord-353633-a4pu6rlu	13	5	non	non	JJ
cord-353633-a4pu6rlu	13	6	-	-	JJ
cord-353633-a4pu6rlu	13	7	invasive	invasive	JJ
cord-353633-a4pu6rlu	13	8	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	13	9	modalities	modality	NNS
cord-353633-a4pu6rlu	13	10	for	for	IN
cord-353633-a4pu6rlu	13	11	the	the	DT
cord-353633-a4pu6rlu	13	12	distinct	distinct	JJ
cord-353633-a4pu6rlu	13	13	stages	stage	NNS
cord-353633-a4pu6rlu	13	14	of	of	IN
cord-353633-a4pu6rlu	13	15	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	13	16	,	,	,
cord-353633-a4pu6rlu	13	17	that	that	WDT
cord-353633-a4pu6rlu	13	18	remain	remain	VBP
cord-353633-a4pu6rlu	13	19	though	though	RB
cord-353633-a4pu6rlu	13	20	to	to	TO
cord-353633-a4pu6rlu	13	21	be	be	VB
cord-353633-a4pu6rlu	13	22	validated	validate	VBN
cord-353633-a4pu6rlu	13	23	in	in	IN
cord-353633-a4pu6rlu	13	24	multiple	multiple	JJ
cord-353633-a4pu6rlu	13	25	,	,	,
cord-353633-a4pu6rlu	13	26	large	large	JJ
cord-353633-a4pu6rlu	13	27	,	,	,
cord-353633-a4pu6rlu	13	28	heterogenous	heterogenous	JJ
cord-353633-a4pu6rlu	13	29	and	and	CC
cord-353633-a4pu6rlu	13	30	independent	independent	JJ
cord-353633-a4pu6rlu	13	31	cohorts	cohort	NNS
cord-353633-a4pu6rlu	13	32	,	,	,
cord-353633-a4pu6rlu	13	33	both	both	CC
cord-353633-a4pu6rlu	13	34	cross	cross	VBP
cord-353633-a4pu6rlu	13	35	-	-	VBZ
cord-353633-a4pu6rlu	13	36	sectionally	sectionally	RB
cord-353633-a4pu6rlu	13	37	as	as	RB
cord-353633-a4pu6rlu	13	38	well	well	RB
cord-353633-a4pu6rlu	13	39	as	as	IN
cord-353633-a4pu6rlu	13	40	prospectively	prospectively	RB
cord-353633-a4pu6rlu	13	41	.	.	.
cord-353633-a4pu6rlu	14	1	Finally	finally	RB
cord-353633-a4pu6rlu	14	2	,	,	,
cord-353633-a4pu6rlu	14	3	they	-PRON-	PRP
cord-353633-a4pu6rlu	14	4	aid	aid	VBP
cord-353633-a4pu6rlu	14	5	in	in	IN
cord-353633-a4pu6rlu	14	6	developing	develop	VBG
cord-353633-a4pu6rlu	14	7	novel	novel	JJ
cord-353633-a4pu6rlu	14	8	therapies	therapy	NNS
cord-353633-a4pu6rlu	14	9	.	.	.
cord-353633-a4pu6rlu	15	1	By	by	IN
cord-353633-a4pu6rlu	15	2	tracing	trace	VBG
cord-353633-a4pu6rlu	15	3	the	the	DT
cord-353633-a4pu6rlu	15	4	flow	flow	NN
cord-353633-a4pu6rlu	15	5	of	of	IN
cord-353633-a4pu6rlu	15	6	information	information	NN
cord-353633-a4pu6rlu	15	7	from	from	IN
cord-353633-a4pu6rlu	15	8	genomics	genomic	NNS
cord-353633-a4pu6rlu	15	9	to	to	IN
cord-353633-a4pu6rlu	15	10	epigenomics	epigenomics	NNP
cord-353633-a4pu6rlu	15	11	,	,	,
cord-353633-a4pu6rlu	15	12	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	15	13	,	,	,
cord-353633-a4pu6rlu	15	14	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	15	15	,	,	,
cord-353633-a4pu6rlu	15	16	metabolomics	metabolomic	NNS
cord-353633-a4pu6rlu	15	17	,	,	,
cord-353633-a4pu6rlu	15	18	lipidomics	lipidomic	NNS
cord-353633-a4pu6rlu	15	19	and	and	CC
cord-353633-a4pu6rlu	15	20	glycomics	glycomic	NNS
cord-353633-a4pu6rlu	15	21	,	,	,
cord-353633-a4pu6rlu	15	22	the	the	DT
cord-353633-a4pu6rlu	15	23	chief	chief	JJ
cord-353633-a4pu6rlu	15	24	contributions	contribution	NNS
cord-353633-a4pu6rlu	15	25	of	of	IN
cord-353633-a4pu6rlu	15	26	these	these	DT
cord-353633-a4pu6rlu	15	27	techniques	technique	NNS
cord-353633-a4pu6rlu	15	28	in	in	IN
cord-353633-a4pu6rlu	15	29	understanding	understanding	NN
cord-353633-a4pu6rlu	15	30	,	,	,
cord-353633-a4pu6rlu	15	31	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	15	32	and	and	CC
cord-353633-a4pu6rlu	15	33	treating	treat	VBG
cord-353633-a4pu6rlu	15	34	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	15	35	are	be	VBP
cord-353633-a4pu6rlu	15	36	summarized	summarize	VBN
cord-353633-a4pu6rlu	15	37	herein	herein	RB
cord-353633-a4pu6rlu	15	38	.	.	.
cord-353633-a4pu6rlu	16	1	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	16	2	is	be	VBZ
cord-353633-a4pu6rlu	16	3	recognized	recognize	VBN
cord-353633-a4pu6rlu	16	4	as	as	IN
cord-353633-a4pu6rlu	16	5	the	the	DT
cord-353633-a4pu6rlu	16	6	most	most	RBS
cord-353633-a4pu6rlu	16	7	common	common	JJ
cord-353633-a4pu6rlu	16	8	liver	liver	NN
cord-353633-a4pu6rlu	16	9	disease	disease	NN
cord-353633-a4pu6rlu	16	10	in	in	IN
cord-353633-a4pu6rlu	16	11	developed	develop	VBN
cord-353633-a4pu6rlu	16	12	countries	country	NNS
cord-353633-a4pu6rlu	16	13	with	with	IN
cord-353633-a4pu6rlu	16	14	its	-PRON-	PRP$
cord-353633-a4pu6rlu	16	15	incidence	incidence	NN
cord-353633-a4pu6rlu	16	16	continuously	continuously	RB
cord-353633-a4pu6rlu	16	17	rising	rise	VBG
cord-353633-a4pu6rlu	16	18	in	in	IN
cord-353633-a4pu6rlu	16	19	parallel	parallel	NN
cord-353633-a4pu6rlu	16	20	to	to	IN
cord-353633-a4pu6rlu	16	21	the	the	DT
cord-353633-a4pu6rlu	16	22	increasing	increase	VBG
cord-353633-a4pu6rlu	16	23	incidences	incidence	NNS
cord-353633-a4pu6rlu	16	24	of	of	IN
cord-353633-a4pu6rlu	16	25	obesity	obesity	NN
cord-353633-a4pu6rlu	16	26	and	and	CC
cord-353633-a4pu6rlu	16	27	type	type	NN
cord-353633-a4pu6rlu	16	28	2	2	CD
cord-353633-a4pu6rlu	16	29	diabetes	diabetes	NN
cord-353633-a4pu6rlu	16	30	(	(	-LRB-
cord-353633-a4pu6rlu	16	31	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	16	32	)	)	-RRB-
cord-353633-a4pu6rlu	16	33	[	[	-LRB-
cord-353633-a4pu6rlu	16	34	1	1	CD
cord-353633-a4pu6rlu	16	35	]	]	-RRB-
cord-353633-a4pu6rlu	16	36	.	.	.
cord-353633-a4pu6rlu	17	1	Significant	significant	JJ
cord-353633-a4pu6rlu	17	2	efforts	effort	NNS
cord-353633-a4pu6rlu	17	3	are	be	VBP
cord-353633-a4pu6rlu	17	4	currently	currently	RB
cord-353633-a4pu6rlu	17	5	underway	underway	JJ
cord-353633-a4pu6rlu	17	6	to	to	TO
cord-353633-a4pu6rlu	17	7	delve	delve	VB
cord-353633-a4pu6rlu	17	8	deeper	deep	JJR
cord-353633-a4pu6rlu	17	9	into	into	IN
cord-353633-a4pu6rlu	17	10	the	the	DT
cord-353633-a4pu6rlu	17	11	pathophysiology	pathophysiology	NN
cord-353633-a4pu6rlu	17	12	of	of	IN
cord-353633-a4pu6rlu	17	13	the	the	DT
cord-353633-a4pu6rlu	17	14	disease	disease	NN
cord-353633-a4pu6rlu	17	15	,	,	,
cord-353633-a4pu6rlu	17	16	to	to	TO
cord-353633-a4pu6rlu	17	17	create	create	VB
cord-353633-a4pu6rlu	17	18	non	non	JJ
cord-353633-a4pu6rlu	17	19	-	-	JJ
cord-353633-a4pu6rlu	17	20	invasive	invasive	JJ
cord-353633-a4pu6rlu	17	21	tools	tool	NNS
cord-353633-a4pu6rlu	17	22	for	for	IN
cord-353633-a4pu6rlu	17	23	its	-PRON-	PRP$
cord-353633-a4pu6rlu	17	24	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	17	25	and	and	CC
cord-353633-a4pu6rlu	17	26	staging	staging	NN
cord-353633-a4pu6rlu	17	27	,	,	,
cord-353633-a4pu6rlu	17	28	as	as	RB
cord-353633-a4pu6rlu	17	29	well	well	RB
cord-353633-a4pu6rlu	17	30	as	as	IN
cord-353633-a4pu6rlu	17	31	to	to	TO
cord-353633-a4pu6rlu	17	32	develop	develop	VB
cord-353633-a4pu6rlu	17	33	highly	highly	RB
cord-353633-a4pu6rlu	17	34	effective	effective	JJ
cord-353633-a4pu6rlu	17	35	and	and	CC
cord-353633-a4pu6rlu	17	36	specific	specific	JJ
cord-353633-a4pu6rlu	17	37	treatments	treatment	NNS
cord-353633-a4pu6rlu	17	38	.	.	.
cord-353633-a4pu6rlu	18	1	The	the	DT
cord-353633-a4pu6rlu	18	2	disease	disease	NN
cord-353633-a4pu6rlu	18	3	is	be	VBZ
cord-353633-a4pu6rlu	18	4	characterized	characterize	VBN
cord-353633-a4pu6rlu	18	5	initially	initially	RB
cord-353633-a4pu6rlu	18	6	by	by	IN
cord-353633-a4pu6rlu	18	7	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	18	8	lipid	lipid	NN
cord-353633-a4pu6rlu	18	9	accumulation	accumulation	NN
cord-353633-a4pu6rlu	18	10	(	(	-LRB-
cord-353633-a4pu6rlu	18	11	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	18	12	fatty	fatty	JJ
cord-353633-a4pu6rlu	18	13	liver	liver	NN
cord-353633-a4pu6rlu	18	14	;	;	:
cord-353633-a4pu6rlu	18	15	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	18	16	)	)	-RRB-
cord-353633-a4pu6rlu	18	17	,	,	,
cord-353633-a4pu6rlu	18	18	that	that	WDT
cord-353633-a4pu6rlu	18	19	can	can	MD
cord-353633-a4pu6rlu	18	20	often	often	RB
cord-353633-a4pu6rlu	18	21	progress	progress	VB
cord-353633-a4pu6rlu	18	22	to	to	IN
cord-353633-a4pu6rlu	18	23	non	non	JJ
cord-353633-a4pu6rlu	18	24	-	-	JJ
cord-353633-a4pu6rlu	18	25	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	18	26	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	18	27	(	(	-LRB-
cord-353633-a4pu6rlu	18	28	NASH	NASH	NNP
cord-353633-a4pu6rlu	18	29	)	)	-RRB-
cord-353633-a4pu6rlu	18	30	,	,	,
cord-353633-a4pu6rlu	18	31	liver	liver	NN
cord-353633-a4pu6rlu	18	32	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	18	33	or	or	CC
cord-353633-a4pu6rlu	18	34	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	18	35	,	,	,
cord-353633-a4pu6rlu	18	36	as	as	IN
cord-353633-a4pu6rlu	18	37	outlined	outline	VBN
cord-353633-a4pu6rlu	18	38	in	in	IN
cord-353633-a4pu6rlu	18	39	detail	detail	NN
cord-353633-a4pu6rlu	18	40	elsewhere	elsewhere	RB
cord-353633-a4pu6rlu	18	41	in	in	IN
cord-353633-a4pu6rlu	18	42	this	this	DT
cord-353633-a4pu6rlu	18	43	special	special	JJ
cord-353633-a4pu6rlu	18	44	issue	issue	NN
cord-353633-a4pu6rlu	18	45	[	[	-LRB-
cord-353633-a4pu6rlu	18	46	1	1	CD
cord-353633-a4pu6rlu	18	47	]	]	-RRB-
cord-353633-a4pu6rlu	18	48	.	.	.
cord-353633-a4pu6rlu	19	1	Several	several	JJ
cord-353633-a4pu6rlu	19	2	triggers	trigger	NNS
cord-353633-a4pu6rlu	19	3	and	and	CC
cord-353633-a4pu6rlu	19	4	series	series	NN
cord-353633-a4pu6rlu	19	5	of	of	IN
cord-353633-a4pu6rlu	19	6	events	event	NNS
cord-353633-a4pu6rlu	19	7	stimulating	stimulate	VBG
cord-353633-a4pu6rlu	19	8	necroinflammatory	necroinflammatory	JJ
cord-353633-a4pu6rlu	19	9	processes	process	NNS
cord-353633-a4pu6rlu	19	10	in	in	IN
cord-353633-a4pu6rlu	19	11	the	the	DT
cord-353633-a4pu6rlu	19	12	liver	liver	NN
cord-353633-a4pu6rlu	19	13	have	have	VBP
cord-353633-a4pu6rlu	19	14	been	be	VBN
cord-353633-a4pu6rlu	19	15	recognized	recognize	VBN
cord-353633-a4pu6rlu	19	16	and	and	CC
cord-353633-a4pu6rlu	19	17	described	describe	VBN
cord-353633-a4pu6rlu	19	18	as	as	IN
cord-353633-a4pu6rlu	19	19	"	"	``
cord-353633-a4pu6rlu	19	20	the	the	DT
cord-353633-a4pu6rlu	19	21	multiple	multiple	JJ
cord-353633-a4pu6rlu	19	22	hit	hit	NN
cord-353633-a4pu6rlu	19	23	"	"	``
cord-353633-a4pu6rlu	19	24	pathogenetic	pathogenetic	JJ
cord-353633-a4pu6rlu	19	25	mechanism	mechanism	NN
cord-353633-a4pu6rlu	19	26	leading	lead	VBG
cord-353633-a4pu6rlu	19	27	to	to	IN
cord-353633-a4pu6rlu	19	28	advanced	advanced	JJ
cord-353633-a4pu6rlu	19	29	NASH	NASH	NNP
cord-353633-a4pu6rlu	19	30	[	[	-LRB-
cord-353633-a4pu6rlu	19	31	2	2	CD
cord-353633-a4pu6rlu	19	32	]	]	-RRB-
cord-353633-a4pu6rlu	19	33	.	.	.
cord-353633-a4pu6rlu	20	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	20	2	,	,	,
cord-353633-a4pu6rlu	20	3	multiple	multiple	JJ
cord-353633-a4pu6rlu	20	4	factors	factor	NNS
cord-353633-a4pu6rlu	20	5	(	(	-LRB-
cord-353633-a4pu6rlu	20	6	such	such	JJ
cord-353633-a4pu6rlu	20	7	as	as	IN
cord-353633-a4pu6rlu	20	8	lack	lack	NN
cord-353633-a4pu6rlu	20	9	of	of	IN
cord-353633-a4pu6rlu	20	10	physical	physical	JJ
cord-353633-a4pu6rlu	20	11	activity	activity	NN
cord-353633-a4pu6rlu	20	12	,	,	,
cord-353633-a4pu6rlu	20	13	unhealthy	unhealthy	JJ
cord-353633-a4pu6rlu	20	14	nutrition	nutrition	NN
cord-353633-a4pu6rlu	20	15	,	,	,
cord-353633-a4pu6rlu	20	16	concomitant	concomitant	JJ
cord-353633-a4pu6rlu	20	17	alcohol	alcohol	NN
cord-353633-a4pu6rlu	20	18	consumption	consumption	NN
cord-353633-a4pu6rlu	20	19	and	and	CC
cord-353633-a4pu6rlu	20	20	presence	presence	NN
cord-353633-a4pu6rlu	20	21	of	of	IN
cord-353633-a4pu6rlu	20	22	other	other	JJ
cord-353633-a4pu6rlu	20	23	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	20	24	diseases	disease	NNS
cord-353633-a4pu6rlu	20	25	)	)	-RRB-
cord-353633-a4pu6rlu	20	26	have	have	VBP
cord-353633-a4pu6rlu	20	27	been	be	VBN
cord-353633-a4pu6rlu	20	28	associated	associate	VBN
cord-353633-a4pu6rlu	20	29	with	with	IN
cord-353633-a4pu6rlu	20	30	increased	increase	VBN
cord-353633-a4pu6rlu	20	31	risk	risk	NN
cord-353633-a4pu6rlu	20	32	of	of	IN
cord-353633-a4pu6rlu	20	33	disease	disease	NN
cord-353633-a4pu6rlu	20	34	progression	progression	NN
cord-353633-a4pu6rlu	20	35	[	[	-LRB-
cord-353633-a4pu6rlu	20	36	3	3	CD
cord-353633-a4pu6rlu	20	37	]	]	-RRB-
cord-353633-a4pu6rlu	20	38	.	.	.
cord-353633-a4pu6rlu	21	1	Still	still	RB
cord-353633-a4pu6rlu	21	2	,	,	,
cord-353633-a4pu6rlu	21	3	we	-PRON-	PRP
cord-353633-a4pu6rlu	21	4	are	be	VBP
cord-353633-a4pu6rlu	21	5	not	not	RB
cord-353633-a4pu6rlu	21	6	able	able	JJ
cord-353633-a4pu6rlu	21	7	to	to	TO
cord-353633-a4pu6rlu	21	8	predict	predict	VB
cord-353633-a4pu6rlu	21	9	with	with	IN
cord-353633-a4pu6rlu	21	10	great	great	JJ
cord-353633-a4pu6rlu	21	11	accuracy	accuracy	NN
cord-353633-a4pu6rlu	21	12	which	which	WDT
cord-353633-a4pu6rlu	21	13	patient	patient	NN
cord-353633-a4pu6rlu	21	14	and	and	CC
cord-353633-a4pu6rlu	21	15	when	when	WRB
cord-353633-a4pu6rlu	21	16	will	will	MD
cord-353633-a4pu6rlu	21	17	develop	develop	VB
cord-353633-a4pu6rlu	21	18	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	21	19	inflammation	inflammation	NN
cord-353633-a4pu6rlu	21	20	or	or	CC
cord-353633-a4pu6rlu	21	21	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	21	22	.	.	.
cord-353633-a4pu6rlu	22	1	J	J	NNP
cord-353633-a4pu6rlu	22	2	o	o	NN
cord-353633-a4pu6rlu	22	3	u	u	NN
cord-353633-a4pu6rlu	22	4	r	r	NN
cord-353633-a4pu6rlu	22	5	n	n	NN
cord-353633-a4pu6rlu	22	6	a	a	DT
cord-353633-a4pu6rlu	22	7	l	l	NN
cord-353633-a4pu6rlu	22	8	P	p	NN
cord-353633-a4pu6rlu	22	9	r	r	NN
cord-353633-a4pu6rlu	22	10	e	e	NN
cord-353633-a4pu6rlu	22	11	-p	-p	NN
cord-353633-a4pu6rlu	23	1	r	r	NN
cord-353633-a4pu6rlu	23	2	o	o	NN
cord-353633-a4pu6rlu	23	3	o	o	NN
cord-353633-a4pu6rlu	23	4	f	f	NN
cord-353633-a4pu6rlu	23	5	13	13	CD
cord-353633-a4pu6rlu	23	6	assessed	assess	VBN
cord-353633-a4pu6rlu	23	7	[	[	-LRB-
cord-353633-a4pu6rlu	23	8	43	43	CD
cord-353633-a4pu6rlu	23	9	]	]	-RRB-
cord-353633-a4pu6rlu	23	10	,	,	,
cord-353633-a4pu6rlu	23	11	and	and	CC
cord-353633-a4pu6rlu	23	12	histologically	histologically	RB
cord-353633-a4pu6rlu	23	13	-	-	HYPH
cord-353633-a4pu6rlu	23	14	proven	prove	VBN
cord-353633-a4pu6rlu	23	15	GWAS	GWAS	NNP
cord-353633-a4pu6rlu	23	16	[	[	-LRB-
cord-353633-a4pu6rlu	23	17	44	44	CD
cord-353633-a4pu6rlu	23	18	]	]	-RRB-
cord-353633-a4pu6rlu	23	19	of	of	IN
cord-353633-a4pu6rlu	23	20	more	more	JJR
cord-353633-a4pu6rlu	23	21	than	than	IN
cord-353633-a4pu6rlu	23	22	10000	10000	CD
cord-353633-a4pu6rlu	23	23	total	total	JJ
cord-353633-a4pu6rlu	23	24	patients	patient	NNS
cord-353633-a4pu6rlu	24	1	each	each	DT
cord-353633-a4pu6rlu	24	2	,	,	,
cord-353633-a4pu6rlu	24	3	re	re	VBN
cord-353633-a4pu6rlu	24	4	-	-	VBN
cord-353633-a4pu6rlu	24	5	affirmed	affirm	VBD
cord-353633-a4pu6rlu	24	6	the	the	DT
cord-353633-a4pu6rlu	24	7	robust	robust	JJ
cord-353633-a4pu6rlu	24	8	clinical	clinical	JJ
cord-353633-a4pu6rlu	24	9	and	and	CC
cord-353633-a4pu6rlu	24	10	histological	histological	JJ
cord-353633-a4pu6rlu	24	11	genome	genome	NN
cord-353633-a4pu6rlu	24	12	-	-	HYPH
cord-353633-a4pu6rlu	24	13	wide	wide	JJ
cord-353633-a4pu6rlu	24	14	associations	association	NNS
cord-353633-a4pu6rlu	24	15	of	of	IN
cord-353633-a4pu6rlu	24	16	PNPLA3	PNPLA3	NNS
cord-353633-a4pu6rlu	24	17	,	,	,
cord-353633-a4pu6rlu	24	18	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	24	19	,	,	,
cord-353633-a4pu6rlu	24	20	GCKR	GCKR	NNP
cord-353633-a4pu6rlu	24	21	,	,	,
cord-353633-a4pu6rlu	24	22	and	and	CC
cord-353633-a4pu6rlu	24	23	HSD17B13	hsd17b13	RB
cord-353633-a4pu6rlu	24	24	.	.	.
cord-353633-a4pu6rlu	25	1	Novel	novel	NN
cord-353633-a4pu6rlu	25	2	fibroinflammatory	fibroinflammatory	JJ
cord-353633-a4pu6rlu	25	3	loci	locus	NNS
cord-353633-a4pu6rlu	25	4	in	in	IN
cord-353633-a4pu6rlu	25	5	SLC30A10	SLC30A10	NNP
cord-353633-a4pu6rlu	25	6	and	and	CC
cord-353633-a4pu6rlu	25	7	SLC39A8	SLC39A8	NNS
cord-353633-a4pu6rlu	25	8	were	be	VBD
cord-353633-a4pu6rlu	25	9	also	also	RB
cord-353633-a4pu6rlu	25	10	studied	study	VBN
cord-353633-a4pu6rlu	25	11	[	[	-LRB-
cord-353633-a4pu6rlu	25	12	43	43	CD
cord-353633-a4pu6rlu	25	13	]	]	-RRB-
cord-353633-a4pu6rlu	25	14	.	.	.
cord-353633-a4pu6rlu	26	1	However	however	RB
cord-353633-a4pu6rlu	26	2	,	,	,
cord-353633-a4pu6rlu	26	3	a	a	DT
cord-353633-a4pu6rlu	26	4	bench	bench	NN
cord-353633-a4pu6rlu	26	5	-	-	HYPH
cord-353633-a4pu6rlu	26	6	to	to	IN
cord-353633-a4pu6rlu	26	7	-	-	HYPH
cord-353633-a4pu6rlu	26	8	bedside	bedside	NN
cord-353633-a4pu6rlu	26	9	conversion	conversion	NN
cord-353633-a4pu6rlu	26	10	of	of	IN
cord-353633-a4pu6rlu	26	11	current	current	JJ
cord-353633-a4pu6rlu	26	12	results	result	NNS
cord-353633-a4pu6rlu	26	13	through	through	IN
cord-353633-a4pu6rlu	26	14	tangible	tangible	JJ
cord-353633-a4pu6rlu	26	15	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	26	16	and	and	CC
cord-353633-a4pu6rlu	26	17	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	26	18	applications	application	NNS
cord-353633-a4pu6rlu	26	19	has	have	VBZ
cord-353633-a4pu6rlu	26	20	yet	yet	RB
cord-353633-a4pu6rlu	26	21	to	to	TO
cord-353633-a4pu6rlu	26	22	take	take	VB
cord-353633-a4pu6rlu	26	23	place	place	NN
cord-353633-a4pu6rlu	26	24	.	.	.
cord-353633-a4pu6rlu	27	1	PNPLA3	PNPLA3	NNS
cord-353633-a4pu6rlu	28	1	rs738409	rs738409	NNP
cord-353633-a4pu6rlu	28	2	constitutes	constitute	VBZ
cord-353633-a4pu6rlu	28	3	the	the	DT
cord-353633-a4pu6rlu	28	4	chief	chief	JJ
cord-353633-a4pu6rlu	28	5	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	28	6	predictor	predictor	NN
cord-353633-a4pu6rlu	28	7	,	,	,
cord-353633-a4pu6rlu	28	8	adjusted	adjust	VBN
cord-353633-a4pu6rlu	28	9	for	for	IN
cord-353633-a4pu6rlu	28	10	known	know	VBN
cord-353633-a4pu6rlu	28	11	risk	risk	NN
cord-353633-a4pu6rlu	28	12	factors	factor	NNS
cord-353633-a4pu6rlu	28	13	(	(	-LRB-
cord-353633-a4pu6rlu	28	14	OR=3.12	or=3.12	NN
cord-353633-a4pu6rlu	28	15	)	)	-RRB-
cord-353633-a4pu6rlu	29	1	[	[	-LRB-
cord-353633-a4pu6rlu	29	2	21	21	CD
cord-353633-a4pu6rlu	29	3	]	]	-RRB-
cord-353633-a4pu6rlu	29	4	.	.	.
cord-353633-a4pu6rlu	30	1	Yet	yet	RB
cord-353633-a4pu6rlu	30	2	its	-PRON-	PRP$
cord-353633-a4pu6rlu	30	3	addition	addition	NN
cord-353633-a4pu6rlu	30	4	in	in	IN
cord-353633-a4pu6rlu	30	5	an	an	DT
cord-353633-a4pu6rlu	30	6	early	early	JJ
cord-353633-a4pu6rlu	30	7	predictive	predictive	JJ
cord-353633-a4pu6rlu	30	8	model	model	NN
cord-353633-a4pu6rlu	30	9	of	of	IN
cord-353633-a4pu6rlu	30	10	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	30	11	,	,	,
cord-353633-a4pu6rlu	30	12	using	use	VBG
cord-353633-a4pu6rlu	30	13	routine	routine	JJ
cord-353633-a4pu6rlu	30	14	variables	variable	NNS
cord-353633-a4pu6rlu	30	15	,	,	,
cord-353633-a4pu6rlu	30	16	contributes	contribute	VBZ
cord-353633-a4pu6rlu	30	17	trivially	trivially	RB
cord-353633-a4pu6rlu	30	18	to	to	TO
cord-353633-a4pu6rlu	30	19	score	score	VB
cord-353633-a4pu6rlu	30	20	accuracy	accuracy	NN
cord-353633-a4pu6rlu	30	21	(	(	-LRB-
cord-353633-a4pu6rlu	30	22	area	area	NN
cord-353633-a4pu6rlu	30	23	under	under	IN
cord-353633-a4pu6rlu	30	24	the	the	DT
cord-353633-a4pu6rlu	30	25	receiver	receiver	NN
cord-353633-a4pu6rlu	30	26	operator	operator	NN
cord-353633-a4pu6rlu	30	27	characteristics	characteristic	NNS
cord-353633-a4pu6rlu	30	28	(	(	-LRB-
cord-353633-a4pu6rlu	30	29	AUROC	AUROC	NNP
cord-353633-a4pu6rlu	30	30	)	)	-RRB-
cord-353633-a4pu6rlu	30	31	=	=	SYM
cord-353633-a4pu6rlu	30	32	0.866	0.866	CD
cord-353633-a4pu6rlu	30	33	and	and	CC
cord-353633-a4pu6rlu	30	34	0.872	0.872	CD
cord-353633-a4pu6rlu	30	35	respectively	respectively	RB
cord-353633-a4pu6rlu	30	36	)	)	-RRB-
cord-353633-a4pu6rlu	31	1	[	[	-LRB-
cord-353633-a4pu6rlu	31	2	45	45	CD
cord-353633-a4pu6rlu	31	3	]	]	-RRB-
cord-353633-a4pu6rlu	31	4	.	.	.
cord-353633-a4pu6rlu	32	1	PNPLA3	PNPLA3	NNP
cord-353633-a4pu6rlu	32	2	is	be	VBZ
cord-353633-a4pu6rlu	32	3	included	include	VBN
cord-353633-a4pu6rlu	32	4	in	in	IN
cord-353633-a4pu6rlu	32	5	the	the	DT
cord-353633-a4pu6rlu	32	6	NASH	NASH	NNP
cord-353633-a4pu6rlu	32	7	Score	Score	NNP
cord-353633-a4pu6rlu	32	8	(	(	-LRB-
cord-353633-a4pu6rlu	32	9	Aspartate	aspartate	JJ
cord-353633-a4pu6rlu	32	10	transaminase	transaminase	NN
cord-353633-a4pu6rlu	32	11	(	(	-LRB-
cord-353633-a4pu6rlu	32	12	AST	ast	NN
cord-353633-a4pu6rlu	32	13	,	,	,
cord-353633-a4pu6rlu	32	14	insulin	insulin	NN
cord-353633-a4pu6rlu	32	15	,	,	,
cord-353633-a4pu6rlu	32	16	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	32	17	genotype	genotype	NN
cord-353633-a4pu6rlu	32	18	)	)	-RRB-
cord-353633-a4pu6rlu	32	19	and	and	CC
cord-353633-a4pu6rlu	32	20	the	the	DT
cord-353633-a4pu6rlu	32	21	ClinLipMet	ClinLipMet	NNP
cord-353633-a4pu6rlu	32	22	Score	Score	NNP
cord-353633-a4pu6rlu	32	23	(	(	-LRB-
cord-353633-a4pu6rlu	32	24	NASH	NASH	NNP
cord-353633-a4pu6rlu	32	25	Clin	Clin	NNP
cord-353633-a4pu6rlu	32	26	Score	Score	NNP
cord-353633-a4pu6rlu	32	27	,	,	,
cord-353633-a4pu6rlu	32	28	metabolomic	metabolomic	NN
cord-353633-a4pu6rlu	32	29	and	and	CC
cord-353633-a4pu6rlu	32	30	lipidomic	lipidomic	JJ
cord-353633-a4pu6rlu	32	31	variables	variable	NNS
cord-353633-a4pu6rlu	32	32	)	)	-RRB-
cord-353633-a4pu6rlu	32	33	with	with	IN
cord-353633-a4pu6rlu	32	34	AUROCs	auroc	NNS
cord-353633-a4pu6rlu	32	35	of	of	IN
cord-353633-a4pu6rlu	32	36	0.778	0.778	CD
cord-353633-a4pu6rlu	32	37	and	and	CC
cord-353633-a4pu6rlu	32	38	0.866	0.866	CD
cord-353633-a4pu6rlu	32	39	respectively	respectively	RB
cord-353633-a4pu6rlu	32	40	,	,	,
cord-353633-a4pu6rlu	32	41	yet	yet	CC
cord-353633-a4pu6rlu	32	42	its	-PRON-	PRP$
cord-353633-a4pu6rlu	32	43	contribution	contribution	NN
cord-353633-a4pu6rlu	32	44	to	to	IN
cord-353633-a4pu6rlu	32	45	NASH	NASH	NNP
cord-353633-a4pu6rlu	32	46	prediction	prediction	NN
cord-353633-a4pu6rlu	32	47	is	be	VBZ
cord-353633-a4pu6rlu	32	48	not	not	RB
cord-353633-a4pu6rlu	32	49	underlined	underline	VBN
cord-353633-a4pu6rlu	32	50	[	[	-LRB-
cord-353633-a4pu6rlu	32	51	46	46	CD
cord-353633-a4pu6rlu	32	52	]	]	-RRB-
cord-353633-a4pu6rlu	32	53	.	.	.
cord-353633-a4pu6rlu	33	1	In	in	IN
cord-353633-a4pu6rlu	33	2	a	a	DT
cord-353633-a4pu6rlu	33	3	more	more	RBR
cord-353633-a4pu6rlu	33	4	recent	recent	JJ
cord-353633-a4pu6rlu	33	5	phenome	phenome	NN
cord-353633-a4pu6rlu	33	6	-	-	HYPH
cord-353633-a4pu6rlu	33	7	genome	genome	NN
cord-353633-a4pu6rlu	33	8	wide	wide	JJ
cord-353633-a4pu6rlu	33	9	study	study	NN
cord-353633-a4pu6rlu	33	10	of	of	IN
cord-353633-a4pu6rlu	33	11	27744	27744	CD
cord-353633-a4pu6rlu	33	12	patients	patient	NNS
cord-353633-a4pu6rlu	33	13	,	,	,
cord-353633-a4pu6rlu	33	14	clinical	clinical	JJ
cord-353633-a4pu6rlu	33	15	data	datum	NNS
cord-353633-a4pu6rlu	33	16	(	(	-LRB-
cord-353633-a4pu6rlu	33	17	age	age	NN
cord-353633-a4pu6rlu	33	18	,	,	,
cord-353633-a4pu6rlu	33	19	sex	sex	NN
cord-353633-a4pu6rlu	33	20	,	,	,
cord-353633-a4pu6rlu	33	21	BMI	BMI	NNP
cord-353633-a4pu6rlu	33	22	,	,	,
cord-353633-a4pu6rlu	33	23	blood	blood	NN
cord-353633-a4pu6rlu	33	24	counts	count	NNS
cord-353633-a4pu6rlu	33	25	)	)	-RRB-
cord-353633-a4pu6rlu	33	26	comprise	comprise	VBP
cord-353633-a4pu6rlu	33	27	a	a	DT
cord-353633-a4pu6rlu	33	28	fitter	fitter	NN
cord-353633-a4pu6rlu	33	29	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	33	30	predictor	predictor	NN
cord-353633-a4pu6rlu	33	31	than	than	IN
cord-353633-a4pu6rlu	33	32	rs738409	rs738409	NNP
cord-353633-a4pu6rlu	33	33	genotyping	genotyping	NNP
cord-353633-a4pu6rlu	33	34	(	(	-LRB-
cord-353633-a4pu6rlu	33	35	AUROC	AUROC	NNP
cord-353633-a4pu6rlu	33	36	=	=	SYM
cord-353633-a4pu6rlu	33	37	0.785	0.785	CD
cord-353633-a4pu6rlu	33	38	and	and	CC
cord-353633-a4pu6rlu	33	39	0.574	0.574	CD
cord-353633-a4pu6rlu	33	40	respectively	respectively	RB
cord-353633-a4pu6rlu	33	41	)	)	-RRB-
cord-353633-a4pu6rlu	33	42	and	and	CC
cord-353633-a4pu6rlu	33	43	have	have	VBP
cord-353633-a4pu6rlu	33	44	34	34	CD
cord-353633-a4pu6rlu	33	45	%	%	NN
cord-353633-a4pu6rlu	33	46	higher	high	JJR
cord-353633-a4pu6rlu	33	47	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	33	48	compared	compare	VBN
cord-353633-a4pu6rlu	33	49	to	to	IN
cord-353633-a4pu6rlu	33	50	genotyping	genotype	VBG
cord-353633-a4pu6rlu	33	51	alone	alone	RB
cord-353633-a4pu6rlu	33	52	.	.	.
cord-353633-a4pu6rlu	34	1	Even	even	RB
cord-353633-a4pu6rlu	34	2	though	though	IN
cord-353633-a4pu6rlu	34	3	rs738409	rs738409	NNP
cord-353633-a4pu6rlu	34	4	carriage	carriage	NN
cord-353633-a4pu6rlu	34	5	was	be	VBD
cord-353633-a4pu6rlu	34	6	associated	associate	VBN
cord-353633-a4pu6rlu	34	7	with	with	IN
cord-353633-a4pu6rlu	34	8	3.1	3.1	CD
cord-353633-a4pu6rlu	34	9	years	year	NNS
cord-353633-a4pu6rlu	34	10	earlier	early	RBR
cord-353633-a4pu6rlu	34	11	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	34	12	detection	detection	NN
cord-353633-a4pu6rlu	34	13	,	,	,
cord-353633-a4pu6rlu	34	14	its	-PRON-	PRP$
cord-353633-a4pu6rlu	34	15	addition	addition	NN
cord-353633-a4pu6rlu	34	16	does	do	VBZ
cord-353633-a4pu6rlu	34	17	not	not	RB
cord-353633-a4pu6rlu	34	18	markedly	markedly	RB
cord-353633-a4pu6rlu	34	19	amplify	amplify	VB
cord-353633-a4pu6rlu	34	20	the	the	DT
cord-353633-a4pu6rlu	34	21	forecasting	forecasting	NN
cord-353633-a4pu6rlu	34	22	model	model	NN
cord-353633-a4pu6rlu	34	23	(	(	-LRB-
cord-353633-a4pu6rlu	34	24	AUROC	AUROC	NNP
cord-353633-a4pu6rlu	34	25	=	=	SYM
cord-353633-a4pu6rlu	34	26	0.788	0.788	CD
cord-353633-a4pu6rlu	34	27	)	)	-RRB-
cord-353633-a4pu6rlu	35	1	[	[	-LRB-
cord-353633-a4pu6rlu	35	2	17	17	CD
cord-353633-a4pu6rlu	35	3	]	]	-RRB-
cord-353633-a4pu6rlu	35	4	.	.	.
cord-353633-a4pu6rlu	36	1	Cumulative	cumulative	JJ
cord-353633-a4pu6rlu	36	2	genetic	genetic	JJ
cord-353633-a4pu6rlu	36	3	risk	risk	NN
cord-353633-a4pu6rlu	36	4	scores	score	NNS
cord-353633-a4pu6rlu	36	5	(	(	-LRB-
cord-353633-a4pu6rlu	36	6	GRS	GRS	NNP
cord-353633-a4pu6rlu	36	7	)	)	-RRB-
cord-353633-a4pu6rlu	36	8	are	be	VBP
cord-353633-a4pu6rlu	36	9	frequently	frequently	RB
cord-353633-a4pu6rlu	36	10	discussed	discuss	VBN
cord-353633-a4pu6rlu	36	11	(	(	-LRB-
cord-353633-a4pu6rlu	36	12	Table	table	NN
cord-353633-a4pu6rlu	36	13	2	2	CD
cord-353633-a4pu6rlu	36	14	)	)	-RRB-
cord-353633-a4pu6rlu	36	15	.	.	.
cord-353633-a4pu6rlu	37	1	A	a	DT
cord-353633-a4pu6rlu	37	2	GRS	GRS	NNP
cord-353633-a4pu6rlu	37	3	of	of	IN
cord-353633-a4pu6rlu	37	4	previously	previously	RB
cord-353633-a4pu6rlu	37	5	mentioned	mention	VBN
cord-353633-a4pu6rlu	37	6	SNPs	snp	NNS
cord-353633-a4pu6rlu	37	7	in	in	IN
cord-353633-a4pu6rlu	37	8	PNPLA3	PNPLA3	NNP
cord-353633-a4pu6rlu	37	9	,	,	,
cord-353633-a4pu6rlu	37	10	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	37	11	,	,	,
cord-353633-a4pu6rlu	37	12	GCKR	GCKR	NNP
cord-353633-a4pu6rlu	37	13	and	and	CC
cord-353633-a4pu6rlu	37	14	MBOAT7	MBOAT7	NNP
cord-353633-a4pu6rlu	37	15	indicates	indicate	VBZ
cord-353633-a4pu6rlu	37	16	a	a	DT
cord-353633-a4pu6rlu	37	17	3-fold	3-fold	CD
cord-353633-a4pu6rlu	37	18	increase	increase	NN
cord-353633-a4pu6rlu	37	19	in	in	IN
cord-353633-a4pu6rlu	37	20	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	37	21	risk	risk	NN
cord-353633-a4pu6rlu	37	22	starting	start	VBG
cord-353633-a4pu6rlu	37	23	from	from	IN
cord-353633-a4pu6rlu	37	24	its	-PRON-	PRP$
cord-353633-a4pu6rlu	37	25	second	second	JJ
cord-353633-a4pu6rlu	37	26	tertile	tertile	NNP
cord-353633-a4pu6rlu	37	27	[	[	-LRB-
cord-353633-a4pu6rlu	37	28	21	21	CD
cord-353633-a4pu6rlu	37	29	]	]	-RRB-
cord-353633-a4pu6rlu	37	30	.	.	.
cord-353633-a4pu6rlu	38	1	When	when	WRB
cord-353633-a4pu6rlu	38	2	coupled	couple	VBN
cord-353633-a4pu6rlu	38	3	with	with	IN
cord-353633-a4pu6rlu	38	4	a	a	DT
cord-353633-a4pu6rlu	38	5	multivariate	multivariate	JJ
cord-353633-a4pu6rlu	38	6	insulin	insulin	NN
cord-353633-a4pu6rlu	38	7	resistance	resistance	NN
cord-353633-a4pu6rlu	38	8	score	score	NN
cord-353633-a4pu6rlu	38	9	,	,	,
cord-353633-a4pu6rlu	38	10	a	a	DT
cord-353633-a4pu6rlu	38	11	GRS	GRS	NNP
cord-353633-a4pu6rlu	38	12	J	J	NNP
cord-353633-a4pu6rlu	38	13	o	o	NN
cord-353633-a4pu6rlu	38	14	u	u	NN
cord-353633-a4pu6rlu	38	15	r	r	NN
cord-353633-a4pu6rlu	38	16	n	n	NN
cord-353633-a4pu6rlu	38	17	a	a	DT
cord-353633-a4pu6rlu	38	18	l	l	NN
cord-353633-a4pu6rlu	38	19	P	p	NN
cord-353633-a4pu6rlu	38	20	r	r	NN
cord-353633-a4pu6rlu	38	21	e	e	NN
cord-353633-a4pu6rlu	39	1	-p	-p	NNP
cord-353633-a4pu6rlu	39	2	r	r	NN
cord-353633-a4pu6rlu	39	3	o	o	NN
cord-353633-a4pu6rlu	39	4	o	o	NN
cord-353633-a4pu6rlu	39	5	f	f	NN
cord-353633-a4pu6rlu	39	6	14	14	CD
cord-353633-a4pu6rlu	39	7	of	of	IN
cord-353633-a4pu6rlu	39	8	PNPLA3	PNPLA3	NNS
cord-353633-a4pu6rlu	39	9	and	and	CC
cord-353633-a4pu6rlu	39	10	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	40	1	SNPs	SNPs	NNP
cord-353633-a4pu6rlu	40	2	detects	detect	VBZ
cord-353633-a4pu6rlu	40	3	NAS	NAS	NNP
cord-353633-a4pu6rlu	40	4	≥	≥	NNP
cord-353633-a4pu6rlu	40	5	3	3	CD
cord-353633-a4pu6rlu	40	6	(	(	-LRB-
cord-353633-a4pu6rlu	40	7	AUROC=0.74	AUROC=0.74	NNP
cord-353633-a4pu6rlu	40	8	)	)	-RRB-
cord-353633-a4pu6rlu	40	9	and	and	CC
cord-353633-a4pu6rlu	40	10	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	40	11	≥	≥	NN
cord-353633-a4pu6rlu	40	12	3	3	CD
cord-353633-a4pu6rlu	40	13	when	when	WRB
cord-353633-a4pu6rlu	40	14	age	age	NN
cord-353633-a4pu6rlu	40	15	included	include	VBD
cord-353633-a4pu6rlu	40	16	(	(	-LRB-
cord-353633-a4pu6rlu	40	17	AUROC	AUROC	NNP
cord-353633-a4pu6rlu	40	18	=	=	SYM
cord-353633-a4pu6rlu	40	19	0.82	0.82	CD
cord-353633-a4pu6rlu	40	20	)	)	-RRB-
cord-353633-a4pu6rlu	40	21	,	,	,
cord-353633-a4pu6rlu	40	22	yet	yet	RB
cord-353633-a4pu6rlu	40	23	GRS	GRS	NNP
cord-353633-a4pu6rlu	40	24	alone	alone	RB
cord-353633-a4pu6rlu	40	25	have	have	VBP
cord-353633-a4pu6rlu	40	26	AUROCs	auroc	NNS
cord-353633-a4pu6rlu	40	27	of	of	IN
cord-353633-a4pu6rlu	40	28	≤	≤	NNS
cord-353633-a4pu6rlu	40	29	0.65	0.65	CD
cord-353633-a4pu6rlu	40	30	[	[	-LRB-
cord-353633-a4pu6rlu	40	31	41	41	CD
cord-353633-a4pu6rlu	40	32	]	]	-RRB-
cord-353633-a4pu6rlu	40	33	.	.	.
cord-353633-a4pu6rlu	41	1	PNPLA3	PNPLA3	NNS
cord-353633-a4pu6rlu	41	2	and	and	CC
cord-353633-a4pu6rlu	41	3	TM6SF2	tm6sf2	JJ
cord-353633-a4pu6rlu	41	4	polymorphisms	polymorphism	NNS
cord-353633-a4pu6rlu	41	5	are	be	VBP
cord-353633-a4pu6rlu	41	6	also	also	RB
cord-353633-a4pu6rlu	41	7	included	include	VBN
cord-353633-a4pu6rlu	41	8	in	in	IN
cord-353633-a4pu6rlu	41	9	a	a	DT
cord-353633-a4pu6rlu	41	10	novel	novel	NN
cord-353633-a4pu6rlu	41	11	NASH	NASH	NNP
cord-353633-a4pu6rlu	41	12	score	score	NN
cord-353633-a4pu6rlu	41	13	alongside	alongside	IN
cord-353633-a4pu6rlu	41	14	diabetes	diabetes	NN
cord-353633-a4pu6rlu	41	15	,	,	,
cord-353633-a4pu6rlu	41	16	insulin	insulin	NN
cord-353633-a4pu6rlu	41	17	resistance	resistance	NN
cord-353633-a4pu6rlu	41	18	,	,	,
cord-353633-a4pu6rlu	41	19	AST	AST	NNP
cord-353633-a4pu6rlu	41	20	and	and	CC
cord-353633-a4pu6rlu	41	21	C	C	NNP
cord-353633-a4pu6rlu	41	22	-	-	HYPH
cord-353633-a4pu6rlu	41	23	reactive	reactive	JJ
cord-353633-a4pu6rlu	41	24	protein	protein	NN
cord-353633-a4pu6rlu	41	25	levels	level	NNS
cord-353633-a4pu6rlu	41	26	,	,	,
cord-353633-a4pu6rlu	41	27	which	which	WDT
cord-353633-a4pu6rlu	41	28	predicts	predict	VBZ
cord-353633-a4pu6rlu	41	29	NASH	NASH	NNP
cord-353633-a4pu6rlu	41	30	more	more	RBR
cord-353633-a4pu6rlu	41	31	effectively	effectively	RB
cord-353633-a4pu6rlu	41	32	compared	compare	VBN
cord-353633-a4pu6rlu	41	33	to	to	IN
cord-353633-a4pu6rlu	41	34	the	the	DT
cord-353633-a4pu6rlu	41	35	older	old	JJR
cord-353633-a4pu6rlu	41	36	NASH	NASH	NNP
cord-353633-a4pu6rlu	41	37	Score	Score	NNP
cord-353633-a4pu6rlu	41	38	(	(	-LRB-
cord-353633-a4pu6rlu	41	39	AUROCs	auroc	NNS
cord-353633-a4pu6rlu	41	40	of	of	IN
cord-353633-a4pu6rlu	41	41	0.787	0.787	CD
cord-353633-a4pu6rlu	41	42	and	and	CC
cord-353633-a4pu6rlu	41	43	0.729	0.729	CD
cord-353633-a4pu6rlu	41	44	respectively	respectively	RB
cord-353633-a4pu6rlu	41	45	)	)	-RRB-
cord-353633-a4pu6rlu	41	46	and	and	CC
cord-353633-a4pu6rlu	41	47	has	have	VBZ
cord-353633-a4pu6rlu	41	48	enhanced	enhance	VBN
cord-353633-a4pu6rlu	41	49	accuracy	accuracy	NN
cord-353633-a4pu6rlu	41	50	in	in	IN
cord-353633-a4pu6rlu	41	51	diabetic	diabetic	JJ
cord-353633-a4pu6rlu	41	52	cohorts	cohort	NNS
cord-353633-a4pu6rlu	41	53	(	(	-LRB-
cord-353633-a4pu6rlu	41	54	AUROC	AUROC	NNP
cord-353633-a4pu6rlu	41	55	=	=	SYM
cord-353633-a4pu6rlu	41	56	0.835	0.835	CD
cord-353633-a4pu6rlu	41	57	)	)	-RRB-
cord-353633-a4pu6rlu	42	1	[	[	-LRB-
cord-353633-a4pu6rlu	42	2	47	47	CD
cord-353633-a4pu6rlu	42	3	]	]	-RRB-
cord-353633-a4pu6rlu	42	4	.	.	.
cord-353633-a4pu6rlu	43	1	Lastly	lastly	RB
cord-353633-a4pu6rlu	43	2	,	,	,
cord-353633-a4pu6rlu	43	3	a	a	DT
cord-353633-a4pu6rlu	43	4	recent	recent	JJ
cord-353633-a4pu6rlu	43	5	investigation	investigation	NN
cord-353633-a4pu6rlu	43	6	of	of	IN
cord-353633-a4pu6rlu	43	7	445452	445452	CD
cord-353633-a4pu6rlu	43	8	individuals	individual	NNS
cord-353633-a4pu6rlu	43	9	formulates	formulate	VBZ
cord-353633-a4pu6rlu	43	10	a	a	DT
cord-353633-a4pu6rlu	43	11	GRS	GRS	NNP
cord-353633-a4pu6rlu	43	12	comprising	comprise	VBG
cord-353633-a4pu6rlu	43	13	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	43	14	,	,	,
cord-353633-a4pu6rlu	43	15	TM6SF	TM6SF	NNP
cord-353633-a4pu6rlu	43	16	AND	and	CC
cord-353633-a4pu6rlu	43	17	HSD17B13	HSD17B13	NNP
cord-353633-a4pu6rlu	43	18	SNPs	SNPs	NNPS
cord-353633-a4pu6rlu	43	19	.	.	.
cord-353633-a4pu6rlu	44	1	A	a	DT
cord-353633-a4pu6rlu	44	2	maximum	maximum	JJ
cord-353633-a4pu6rlu	44	3	risk	risk	NN
cord-353633-a4pu6rlu	44	4	score	score	NN
cord-353633-a4pu6rlu	44	5	of	of	IN
cord-353633-a4pu6rlu	44	6	6	6	CD
cord-353633-a4pu6rlu	44	7	designates	designate	VBZ
cord-353633-a4pu6rlu	44	8	a	a	DT
cord-353633-a4pu6rlu	44	9	26	26	CD
cord-353633-a4pu6rlu	44	10	%	%	NN
cord-353633-a4pu6rlu	44	11	increase	increase	NN
cord-353633-a4pu6rlu	44	12	in	in	IN
cord-353633-a4pu6rlu	44	13	alanine	alanine	JJ
cord-353633-a4pu6rlu	44	14	aminotransferase	aminotransferase	NN
cord-353633-a4pu6rlu	44	15	(	(	-LRB-
cord-353633-a4pu6rlu	44	16	ALT	ALT	NNP
cord-353633-a4pu6rlu	44	17	)	)	-RRB-
cord-353633-a4pu6rlu	44	18	levels	level	NNS
cord-353633-a4pu6rlu	44	19	and	and	CC
cord-353633-a4pu6rlu	44	20	a	a	DT
cord-353633-a4pu6rlu	44	21	pronounced	pronounced	JJ
cord-353633-a4pu6rlu	44	22	risk	risk	NN
cord-353633-a4pu6rlu	44	23	of	of	IN
cord-353633-a4pu6rlu	44	24	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	44	25	and	and	CC
cord-353633-a4pu6rlu	44	26	HCC	HCC	NNP
cord-353633-a4pu6rlu	44	27	(	(	-LRB-
cord-353633-a4pu6rlu	44	28	OR=12	OR=12	NNP
cord-353633-a4pu6rlu	44	29	and	and	CC
cord-353633-a4pu6rlu	44	30	29	29	CD
cord-353633-a4pu6rlu	44	31	respectively	respectively	RB
cord-353633-a4pu6rlu	44	32	)	)	-RRB-
cord-353633-a4pu6rlu	45	1	[	[	-LRB-
cord-353633-a4pu6rlu	45	2	48	48	CD
cord-353633-a4pu6rlu	45	3	]	]	-RRB-
cord-353633-a4pu6rlu	45	4	.	.	.
cord-353633-a4pu6rlu	46	1	Genetic	genetic	JJ
cord-353633-a4pu6rlu	46	2	testing	testing	NN
cord-353633-a4pu6rlu	46	3	in	in	IN
cord-353633-a4pu6rlu	46	4	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	46	5	is	be	VBZ
cord-353633-a4pu6rlu	46	6	currently	currently	RB
cord-353633-a4pu6rlu	46	7	not	not	RB
cord-353633-a4pu6rlu	46	8	recommended	recommend	VBN
cord-353633-a4pu6rlu	46	9	by	by	IN
cord-353633-a4pu6rlu	46	10	the	the	DT
cord-353633-a4pu6rlu	46	11	American	American	NNP
cord-353633-a4pu6rlu	46	12	Association	Association	NNP
cord-353633-a4pu6rlu	46	13	for	for	IN
cord-353633-a4pu6rlu	46	14	the	the	DT
cord-353633-a4pu6rlu	46	15	Study	Study	NNP
cord-353633-a4pu6rlu	46	16	of	of	IN
cord-353633-a4pu6rlu	46	17	Liver	Liver	NNP
cord-353633-a4pu6rlu	46	18	Diseases	Diseases	NNPS
cord-353633-a4pu6rlu	46	19	[	[	-LRB-
cord-353633-a4pu6rlu	46	20	49	49	CD
cord-353633-a4pu6rlu	46	21	]	]	-RRB-
cord-353633-a4pu6rlu	46	22	.	.	.
cord-353633-a4pu6rlu	47	1	Thus	thus	RB
cord-353633-a4pu6rlu	47	2	far	far	RB
cord-353633-a4pu6rlu	47	3	,	,	,
cord-353633-a4pu6rlu	47	4	genomics	genomic	NNS
cord-353633-a4pu6rlu	47	5	have	have	VBP
cord-353633-a4pu6rlu	47	6	not	not	RB
cord-353633-a4pu6rlu	47	7	identified	identify	VBN
cord-353633-a4pu6rlu	47	8	a	a	DT
cord-353633-a4pu6rlu	47	9	consistent	consistent	JJ
cord-353633-a4pu6rlu	47	10	marker	marker	NN
cord-353633-a4pu6rlu	47	11	that	that	WDT
cord-353633-a4pu6rlu	47	12	reflects	reflect	VBZ
cord-353633-a4pu6rlu	47	13	the	the	DT
cord-353633-a4pu6rlu	47	14	accurate	accurate	JJ
cord-353633-a4pu6rlu	47	15	histologic	histologic	JJ
cord-353633-a4pu6rlu	47	16	features	feature	NNS
cord-353633-a4pu6rlu	47	17	of	of	IN
cord-353633-a4pu6rlu	47	18	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	47	19	,	,	,
cord-353633-a4pu6rlu	47	20	partially	partially	RB
cord-353633-a4pu6rlu	47	21	owing	owe	VBG
cord-353633-a4pu6rlu	47	22	to	to	IN
cord-353633-a4pu6rlu	47	23	limited	limited	JJ
cord-353633-a4pu6rlu	47	24	population	population	NN
cord-353633-a4pu6rlu	47	25	sizes	size	NNS
cord-353633-a4pu6rlu	47	26	,	,	,
cord-353633-a4pu6rlu	47	27	inconsistent	inconsistent	JJ
cord-353633-a4pu6rlu	47	28	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	47	29	validation	validation	NN
cord-353633-a4pu6rlu	47	30	methods	method	NNS
cord-353633-a4pu6rlu	47	31	and	and	CC
cord-353633-a4pu6rlu	47	32	scarcity	scarcity	NN
cord-353633-a4pu6rlu	47	33	of	of	IN
cord-353633-a4pu6rlu	47	34	biopsy	biopsy	NN
cord-353633-a4pu6rlu	47	35	-	-	HYPH
cord-353633-a4pu6rlu	47	36	confirmed	confirm	VBN
cord-353633-a4pu6rlu	47	37	models	model	NNS
cord-353633-a4pu6rlu	47	38	.	.	.
cord-353633-a4pu6rlu	48	1	Most	most	RBS
cord-353633-a4pu6rlu	48	2	importantly	importantly	RB
cord-353633-a4pu6rlu	48	3	,	,	,
cord-353633-a4pu6rlu	48	4	genomics	genomic	NNS
cord-353633-a4pu6rlu	48	5	are	be	VBP
cord-353633-a4pu6rlu	48	6	not	not	RB
cord-353633-a4pu6rlu	48	7	dynamic	dynamic	JJ
cord-353633-a4pu6rlu	48	8	processes	process	NNS
cord-353633-a4pu6rlu	48	9	,	,	,
cord-353633-a4pu6rlu	48	10	thus	thus	RB
cord-353633-a4pu6rlu	48	11	they	-PRON-	PRP
cord-353633-a4pu6rlu	48	12	can	can	MD
cord-353633-a4pu6rlu	48	13	not	not	RB
cord-353633-a4pu6rlu	48	14	reflect	reflect	VB
cord-353633-a4pu6rlu	48	15	the	the	DT
cord-353633-a4pu6rlu	48	16	impact	impact	NN
cord-353633-a4pu6rlu	48	17	of	of	IN
cord-353633-a4pu6rlu	48	18	environmental	environmental	JJ
cord-353633-a4pu6rlu	48	19	factors	factor	NNS
cord-353633-a4pu6rlu	48	20	(	(	-LRB-
cord-353633-a4pu6rlu	48	21	high	high	JJ
cord-353633-a4pu6rlu	48	22	caloric	caloric	JJ
cord-353633-a4pu6rlu	48	23	intake	intake	NN
cord-353633-a4pu6rlu	48	24	,	,	,
cord-353633-a4pu6rlu	48	25	presence	presence	NN
cord-353633-a4pu6rlu	48	26	of	of	IN
cord-353633-a4pu6rlu	48	27	obesity	obesity	NN
cord-353633-a4pu6rlu	48	28	,	,	,
cord-353633-a4pu6rlu	48	29	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	48	30	etc	etc	FW
cord-353633-a4pu6rlu	48	31	.	.	.
cord-353633-a4pu6rlu	48	32	)	)	-RRB-
cord-353633-a4pu6rlu	49	1	in	in	IN
cord-353633-a4pu6rlu	49	2	the	the	DT
cord-353633-a4pu6rlu	49	3	pathogenesis	pathogenesis	NN
cord-353633-a4pu6rlu	49	4	and	and	CC
cord-353633-a4pu6rlu	49	5	progression	progression	NN
cord-353633-a4pu6rlu	49	6	of	of	IN
cord-353633-a4pu6rlu	49	7	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	49	8	.	.	.
cord-353633-a4pu6rlu	50	1	Multi	multi	JJ
cord-353633-a4pu6rlu	50	2	-	-	JJ
cord-353633-a4pu6rlu	50	3	gene	gene	JJ
cord-353633-a4pu6rlu	50	4	models	model	NNS
cord-353633-a4pu6rlu	50	5	are	be	VBP
cord-353633-a4pu6rlu	50	6	promising	promising	JJ
cord-353633-a4pu6rlu	50	7	tools	tool	NNS
cord-353633-a4pu6rlu	50	8	of	of	IN
cord-353633-a4pu6rlu	50	9	patient	patient	JJ
cord-353633-a4pu6rlu	50	10	risk	risk	NN
cord-353633-a4pu6rlu	50	11	stratification	stratification	NN
cord-353633-a4pu6rlu	50	12	but	but	CC
cord-353633-a4pu6rlu	50	13	require	require	VB
cord-353633-a4pu6rlu	50	14	additional	additional	JJ
cord-353633-a4pu6rlu	50	15	validation	validation	NN
cord-353633-a4pu6rlu	50	16	.	.	.
cord-353633-a4pu6rlu	51	1	PNPLA3	PNPLA3	NNP
cord-353633-a4pu6rlu	51	2	has	have	VBZ
cord-353633-a4pu6rlu	51	3	also	also	RB
cord-353633-a4pu6rlu	51	4	been	be	VBN
cord-353633-a4pu6rlu	51	5	investigated	investigate	VBN
cord-353633-a4pu6rlu	51	6	through	through	IN
cord-353633-a4pu6rlu	51	7	early	early	JJ
cord-353633-a4pu6rlu	51	8	genetic	genetic	JJ
cord-353633-a4pu6rlu	51	9	interventions	intervention	NNS
cord-353633-a4pu6rlu	51	10	.	.	.
cord-353633-a4pu6rlu	52	1	Preand	preand	JJ
cord-353633-a4pu6rlu	52	2	post	post	JJ
cord-353633-a4pu6rlu	52	3	-	-	JJ
cord-353633-a4pu6rlu	52	4	translational	translational	JJ
cord-353633-a4pu6rlu	52	5	silencing	silencing	NN
cord-353633-a4pu6rlu	52	6	of	of	IN
cord-353633-a4pu6rlu	52	7	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	52	8	in	in	IN
cord-353633-a4pu6rlu	52	9	p.	p.	NN
cord-353633-a4pu6rlu	53	1	I148	i148	VB
cord-353633-a4pu6rlu	54	1	M	M	NNP
cord-353633-a4pu6rlu	54	2	knock	knock	VB
cord-353633-a4pu6rlu	54	3	-	-	HYPH
cord-353633-a4pu6rlu	54	4	in	in	RP
cord-353633-a4pu6rlu	54	5	mice	mouse	NNS
cord-353633-a4pu6rlu	55	1	J	J	NNP
cord-353633-a4pu6rlu	55	2	o	o	NN
cord-353633-a4pu6rlu	55	3	u	u	NN
cord-353633-a4pu6rlu	55	4	r	r	NN
cord-353633-a4pu6rlu	55	5	n	n	NN
cord-353633-a4pu6rlu	55	6	a	a	DT
cord-353633-a4pu6rlu	55	7	l	l	NN
cord-353633-a4pu6rlu	55	8	P	p	NN
cord-353633-a4pu6rlu	55	9	r	r	NN
cord-353633-a4pu6rlu	55	10	e	e	NN
cord-353633-a4pu6rlu	55	11	-p	-p	NN
cord-353633-a4pu6rlu	55	12	r	r	NN
cord-353633-a4pu6rlu	55	13	o	o	NN
cord-353633-a4pu6rlu	56	1	o	o	NNP
cord-353633-a4pu6rlu	56	2	f	f	NNP
cord-353633-a4pu6rlu	56	3	15	15	CD
cord-353633-a4pu6rlu	56	4	challenged	challenge	VBD
cord-353633-a4pu6rlu	56	5	with	with	IN
cord-353633-a4pu6rlu	56	6	a	a	DT
cord-353633-a4pu6rlu	56	7	sucrose	sucrose	NN
cord-353633-a4pu6rlu	56	8	-	-	HYPH
cord-353633-a4pu6rlu	56	9	rich	rich	JJ
cord-353633-a4pu6rlu	56	10	diet	diet	NN
cord-353633-a4pu6rlu	56	11	drastically	drastically	RB
cord-353633-a4pu6rlu	56	12	improves	improve	VBZ
cord-353633-a4pu6rlu	56	13	intrahepatic	intrahepatic	JJ
cord-353633-a4pu6rlu	56	14	fat	fat	NN
cord-353633-a4pu6rlu	56	15	profiles	profile	NNS
cord-353633-a4pu6rlu	56	16	[	[	-LRB-
cord-353633-a4pu6rlu	56	17	50	50	CD
cord-353633-a4pu6rlu	56	18	,	,	,
cord-353633-a4pu6rlu	56	19	51	51	CD
cord-353633-a4pu6rlu	56	20	]	]	-RRB-
cord-353633-a4pu6rlu	56	21	.	.	.
cord-353633-a4pu6rlu	57	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	57	2	,	,	,
cord-353633-a4pu6rlu	57	3	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	57	4	silencing	silence	VBG
cord-353633-a4pu6rlu	57	5	ameliorates	ameliorate	VBZ
cord-353633-a4pu6rlu	57	6	steatosis	steatosis	NN
cord-353633-a4pu6rlu	57	7	and	and	CC
cord-353633-a4pu6rlu	57	8	NAS	NAS	NNP
cord-353633-a4pu6rlu	57	9	independent	independent	NN
cord-353633-a4pu6rlu	57	10	of	of	IN
cord-353633-a4pu6rlu	57	11	genotype	genotype	NN
cord-353633-a4pu6rlu	57	12	,	,	,
cord-353633-a4pu6rlu	57	13	and	and	CC
cord-353633-a4pu6rlu	57	14	improves	improve	VBZ
cord-353633-a4pu6rlu	57	15	inflammation	inflammation	NN
cord-353633-a4pu6rlu	57	16	,	,	,
cord-353633-a4pu6rlu	57	17	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	57	18	and	and	CC
cord-353633-a4pu6rlu	57	19	levels	level	NNS
cord-353633-a4pu6rlu	57	20	of	of	IN
cord-353633-a4pu6rlu	57	21	acute	acute	JJ
cord-353633-a4pu6rlu	57	22	phase	phase	NN
cord-353633-a4pu6rlu	57	23	,	,	,
cord-353633-a4pu6rlu	57	24	chemo	chemo	NN
cord-353633-a4pu6rlu	57	25	-	-	HYPH
cord-353633-a4pu6rlu	57	26	attractant	attractant	NN
cord-353633-a4pu6rlu	57	27	and	and	CC
cord-353633-a4pu6rlu	57	28	pro	pro	JJ
cord-353633-a4pu6rlu	57	29	-	-	JJ
cord-353633-a4pu6rlu	57	30	fibrotic	fibrotic	JJ
cord-353633-a4pu6rlu	57	31	proteins	protein	NNS
cord-353633-a4pu6rlu	57	32	,	,	,
cord-353633-a4pu6rlu	57	33	in	in	IN
cord-353633-a4pu6rlu	57	34	p.	p.	NN
cord-353633-a4pu6rlu	58	1	I148	I148	NNP
cord-353633-a4pu6rlu	58	2	M	M	NNP
cord-353633-a4pu6rlu	58	3	knockin	knockin	NNP
cord-353633-a4pu6rlu	58	4	mice	mouse	NNS
cord-353633-a4pu6rlu	58	5	fed	feed	VBD
cord-353633-a4pu6rlu	58	6	a	a	DT
cord-353633-a4pu6rlu	58	7	NASH	NASH	NNP
cord-353633-a4pu6rlu	58	8	-	-	HYPH
cord-353633-a4pu6rlu	58	9	inducing	induce	VBG
cord-353633-a4pu6rlu	58	10	diet	diet	NN
cord-353633-a4pu6rlu	58	11	[	[	-LRB-
cord-353633-a4pu6rlu	58	12	51	51	CD
cord-353633-a4pu6rlu	58	13	]	]	-RRB-
cord-353633-a4pu6rlu	58	14	.	.	.
cord-353633-a4pu6rlu	59	1	However	however	RB
cord-353633-a4pu6rlu	59	2	,	,	,
cord-353633-a4pu6rlu	59	3	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	59	4	protects	protect	VBZ
cord-353633-a4pu6rlu	59	5	from	from	IN
cord-353633-a4pu6rlu	59	6	hypercholesterolemia	hypercholesterolemia	NN
cord-353633-a4pu6rlu	59	7	,	,	,
cord-353633-a4pu6rlu	59	8	gallstones	gallstone	NNS
cord-353633-a4pu6rlu	59	9	,	,	,
cord-353633-a4pu6rlu	59	10	gout	gout	NN
cord-353633-a4pu6rlu	59	11	and	and	CC
cord-353633-a4pu6rlu	59	12	acne	acne	NN
cord-353633-a4pu6rlu	59	13	in	in	IN
cord-353633-a4pu6rlu	59	14	humans	human	NNS
cord-353633-a4pu6rlu	59	15	[	[	-LRB-
cord-353633-a4pu6rlu	59	16	52	52	CD
cord-353633-a4pu6rlu	59	17	]	]	-RRB-
cord-353633-a4pu6rlu	59	18	,	,	,
cord-353633-a4pu6rlu	59	19	therefore	therefore	RB
cord-353633-a4pu6rlu	59	20	future	future	JJ
cord-353633-a4pu6rlu	59	21	pilot	pilot	NN
cord-353633-a4pu6rlu	59	22	studies	study	NNS
cord-353633-a4pu6rlu	59	23	must	must	MD
cord-353633-a4pu6rlu	59	24	be	be	VB
cord-353633-a4pu6rlu	59	25	carefully	carefully	RB
cord-353633-a4pu6rlu	59	26	considered	consider	VBN
cord-353633-a4pu6rlu	59	27	.	.	.
cord-353633-a4pu6rlu	60	1	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	60	2	is	be	VBZ
cord-353633-a4pu6rlu	60	3	another	another	DT
cord-353633-a4pu6rlu	60	4	possible	possible	JJ
cord-353633-a4pu6rlu	60	5	target	target	NN
cord-353633-a4pu6rlu	60	6	,	,	,
cord-353633-a4pu6rlu	60	7	yet	yet	CC
cord-353633-a4pu6rlu	60	8	its	-PRON-	PRP$
cord-353633-a4pu6rlu	60	9	substantial	substantial	JJ
cord-353633-a4pu6rlu	60	10	cardioprotective	cardioprotective	JJ
cord-353633-a4pu6rlu	60	11	effects	effect	NNS
cord-353633-a4pu6rlu	60	12	[	[	-LRB-
cord-353633-a4pu6rlu	60	13	53	53	CD
cord-353633-a4pu6rlu	60	14	]	]	-RRB-
cord-353633-a4pu6rlu	60	15	indicate	indicate	VBP
cord-353633-a4pu6rlu	60	16	the	the	DT
cord-353633-a4pu6rlu	60	17	complexity	complexity	NN
cord-353633-a4pu6rlu	60	18	of	of	IN
cord-353633-a4pu6rlu	60	19	such	such	PDT
cord-353633-a4pu6rlu	60	20	an	an	DT
cord-353633-a4pu6rlu	60	21	approach	approach	NN
cord-353633-a4pu6rlu	60	22	,	,	,
cord-353633-a4pu6rlu	60	23	since	since	IN
cord-353633-a4pu6rlu	60	24	the	the	DT
cord-353633-a4pu6rlu	60	25	chief	chief	JJ
cord-353633-a4pu6rlu	60	26	cause	cause	NN
cord-353633-a4pu6rlu	60	27	of	of	IN
cord-353633-a4pu6rlu	60	28	death	death	NN
cord-353633-a4pu6rlu	60	29	in	in	IN
cord-353633-a4pu6rlu	60	30	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	60	31	patients	patient	NNS
cord-353633-a4pu6rlu	60	32	is	be	VBZ
cord-353633-a4pu6rlu	60	33	cardiovascular	cardiovascular	JJ
cord-353633-a4pu6rlu	60	34	disease	disease	NN
cord-353633-a4pu6rlu	60	35	[	[	-LRB-
cord-353633-a4pu6rlu	60	36	49	49	CD
cord-353633-a4pu6rlu	60	37	]	]	-RRB-
cord-353633-a4pu6rlu	60	38	.	.	.
cord-353633-a4pu6rlu	61	1	Patient	patient	JJ
cord-353633-a4pu6rlu	61	2	genotyping	genotyping	NN
cord-353633-a4pu6rlu	61	3	prior	prior	RB
cord-353633-a4pu6rlu	61	4	to	to	IN
cord-353633-a4pu6rlu	61	5	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	61	6	scheme	scheme	NN
cord-353633-a4pu6rlu	61	7	initiation	initiation	NN
cord-353633-a4pu6rlu	61	8	implies	imply	VBZ
cord-353633-a4pu6rlu	61	9	compelling	compelling	JJ
cord-353633-a4pu6rlu	61	10	curative	curative	JJ
cord-353633-a4pu6rlu	61	11	applications	application	NNS
cord-353633-a4pu6rlu	61	12	.	.	.
cord-353633-a4pu6rlu	62	1	For	for	IN
cord-353633-a4pu6rlu	62	2	instance	instance	NN
cord-353633-a4pu6rlu	62	3	,	,	,
cord-353633-a4pu6rlu	62	4	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	62	5	p.	p.	NN
cord-353633-a4pu6rlu	63	1	I148	I148	NNP
cord-353633-a4pu6rlu	63	2	M	m	CD
cord-353633-a4pu6rlu	63	3	carriers	carrier	NNS
cord-353633-a4pu6rlu	63	4	would	would	MD
cord-353633-a4pu6rlu	63	5	not	not	RB
cord-353633-a4pu6rlu	63	6	respond	respond	VB
cord-353633-a4pu6rlu	63	7	to	to	IN
cord-353633-a4pu6rlu	63	8	statins	statin	NNS
cord-353633-a4pu6rlu	63	9	and	and	CC
cord-353633-a4pu6rlu	63	10	inhibitors	inhibitor	NNS
cord-353633-a4pu6rlu	63	11	of	of	IN
cord-353633-a4pu6rlu	63	12	de	de	NNP
cord-353633-a4pu6rlu	63	13	novo	novo	NNP
cord-353633-a4pu6rlu	63	14	lipogenesis	lipogenesis	NNP
cord-353633-a4pu6rlu	63	15	,	,	,
cord-353633-a4pu6rlu	63	16	in	in	IN
cord-353633-a4pu6rlu	63	17	contrast	contrast	NN
cord-353633-a4pu6rlu	63	18	to	to	IN
cord-353633-a4pu6rlu	63	19	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	63	20	and	and	CC
cord-353633-a4pu6rlu	63	21	GCKR	GCKR	NNP
cord-353633-a4pu6rlu	63	22	carriers	carrier	NNS
cord-353633-a4pu6rlu	63	23	[	[	-LRB-
cord-353633-a4pu6rlu	63	24	54	54	CD
cord-353633-a4pu6rlu	63	25	]	]	-RRB-
cord-353633-a4pu6rlu	63	26	.	.	.
cord-353633-a4pu6rlu	64	1	Moreover	moreover	RB
cord-353633-a4pu6rlu	64	2	,	,	,
cord-353633-a4pu6rlu	64	3	HSD17B13	HSD17B13	NNP
cord-353633-a4pu6rlu	64	4	has	have	VBZ
cord-353633-a4pu6rlu	64	5	already	already	RB
cord-353633-a4pu6rlu	64	6	been	be	VBN
cord-353633-a4pu6rlu	64	7	implied	imply	VBN
cord-353633-a4pu6rlu	64	8	as	as	IN
cord-353633-a4pu6rlu	64	9	a	a	DT
cord-353633-a4pu6rlu	64	10	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	64	11	target	target	NN
cord-353633-a4pu6rlu	64	12	[	[	-LRB-
cord-353633-a4pu6rlu	64	13	42	42	CD
cord-353633-a4pu6rlu	64	14	]	]	-RRB-
cord-353633-a4pu6rlu	64	15	,	,	,
cord-353633-a4pu6rlu	64	16	while	while	IN
cord-353633-a4pu6rlu	64	17	it	-PRON-	PRP
cord-353633-a4pu6rlu	64	18	was	be	VBD
cord-353633-a4pu6rlu	64	19	recently	recently	RB
cord-353633-a4pu6rlu	64	20	established	establish	VBN
cord-353633-a4pu6rlu	64	21	that	that	DT
cord-353633-a4pu6rlu	64	22	carriage	carriage	NN
cord-353633-a4pu6rlu	64	23	of	of	IN
cord-353633-a4pu6rlu	64	24	HSD17B13	HSD17B13	NNP
cord-353633-a4pu6rlu	64	25	rs6834314	rs6834314	NNP
cord-353633-a4pu6rlu	64	26	diminishes	diminish	VBZ
cord-353633-a4pu6rlu	64	27	the	the	DT
cord-353633-a4pu6rlu	64	28	fibrotic	fibrotic	JJ
cord-353633-a4pu6rlu	64	29	effects	effect	NNS
cord-353633-a4pu6rlu	64	30	of	of	IN
cord-353633-a4pu6rlu	64	31	PNPLA3	PNPLA3	NNS
cord-353633-a4pu6rlu	64	32	rs738409	rs738409	NNP
cord-353633-a4pu6rlu	64	33	,	,	,
cord-353633-a4pu6rlu	64	34	thus	thus	RB
cord-353633-a4pu6rlu	64	35	indicating	indicate	VBG
cord-353633-a4pu6rlu	64	36	a	a	DT
cord-353633-a4pu6rlu	64	37	novel	novel	JJ
cord-353633-a4pu6rlu	64	38	objective	objective	NN
cord-353633-a4pu6rlu	64	39	for	for	IN
cord-353633-a4pu6rlu	64	40	pathway	pathway	NN
cord-353633-a4pu6rlu	64	41	-	-	HYPH
cord-353633-a4pu6rlu	64	42	targeting	target	VBG
cord-353633-a4pu6rlu	64	43	therapies	therapy	NNS
cord-353633-a4pu6rlu	64	44	[	[	-LRB-
cord-353633-a4pu6rlu	64	45	55	55	CD
cord-353633-a4pu6rlu	64	46	]	]	-RRB-
cord-353633-a4pu6rlu	64	47	.	.	.
cord-353633-a4pu6rlu	65	1	Further	further	JJ
cord-353633-a4pu6rlu	65	2	research	research	NN
cord-353633-a4pu6rlu	65	3	could	could	MD
cord-353633-a4pu6rlu	65	4	uncover	uncover	VB
cord-353633-a4pu6rlu	65	5	powerful	powerful	JJ
cord-353633-a4pu6rlu	65	6	hierarchical	hierarchical	JJ
cord-353633-a4pu6rlu	65	7	and	and	CC
cord-353633-a4pu6rlu	65	8	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	65	9	tools	tool	NNS
cord-353633-a4pu6rlu	65	10	in	in	IN
cord-353633-a4pu6rlu	65	11	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	65	12	genomics	genomic	NNS
cord-353633-a4pu6rlu	65	13	,	,	,
cord-353633-a4pu6rlu	65	14	jumpstarting	jumpstart	VBG
cord-353633-a4pu6rlu	65	15	a	a	DT
cord-353633-a4pu6rlu	65	16	new	new	JJ
cord-353633-a4pu6rlu	65	17	era	era	NN
cord-353633-a4pu6rlu	65	18	of	of	IN
cord-353633-a4pu6rlu	65	19	clinicogenomics	clinicogenomic	NNS
cord-353633-a4pu6rlu	65	20	.	.	.
cord-353633-a4pu6rlu	66	1	J	J	NNP
cord-353633-a4pu6rlu	66	2	o	o	NN
cord-353633-a4pu6rlu	66	3	u	u	NN
cord-353633-a4pu6rlu	66	4	r	r	NN
cord-353633-a4pu6rlu	66	5	n	n	NN
cord-353633-a4pu6rlu	66	6	a	a	DT
cord-353633-a4pu6rlu	66	7	l	l	NN
cord-353633-a4pu6rlu	66	8	P	p	NN
cord-353633-a4pu6rlu	66	9	r	r	NN
cord-353633-a4pu6rlu	66	10	e	e	NN
cord-353633-a4pu6rlu	66	11	-p	-p	NN
cord-353633-a4pu6rlu	67	1	r	r	NN
cord-353633-a4pu6rlu	67	2	o	o	NN
cord-353633-a4pu6rlu	67	3	o	o	NN
cord-353633-a4pu6rlu	67	4	f	f	NN
cord-353633-a4pu6rlu	67	5	16	16	CD
cord-353633-a4pu6rlu	67	6	progression	progression	NN
cord-353633-a4pu6rlu	67	7	of	of	IN
cord-353633-a4pu6rlu	67	8	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	67	9	.	.	.
cord-353633-a4pu6rlu	68	1	Given	give	VBN
cord-353633-a4pu6rlu	68	2	the	the	DT
cord-353633-a4pu6rlu	68	3	continuous	continuous	JJ
cord-353633-a4pu6rlu	68	4	evolvement	evolvement	NN
cord-353633-a4pu6rlu	68	5	of	of	IN
cord-353633-a4pu6rlu	68	6	personalized	personalized	JJ
cord-353633-a4pu6rlu	68	7	medicine	medicine	NN
cord-353633-a4pu6rlu	68	8	,	,	,
cord-353633-a4pu6rlu	68	9	we	-PRON-	PRP
cord-353633-a4pu6rlu	68	10	expect	expect	VBP
cord-353633-a4pu6rlu	68	11	the	the	DT
cord-353633-a4pu6rlu	68	12	information	information	NN
cord-353633-a4pu6rlu	68	13	from	from	IN
cord-353633-a4pu6rlu	68	14	genomics	genomic	NNS
cord-353633-a4pu6rlu	68	15	to	to	TO
cord-353633-a4pu6rlu	68	16	be	be	VB
cord-353633-a4pu6rlu	68	17	used	use	VBN
cord-353633-a4pu6rlu	68	18	in	in	IN
cord-353633-a4pu6rlu	68	19	the	the	DT
cord-353633-a4pu6rlu	68	20	near	near	JJ
cord-353633-a4pu6rlu	68	21	future	future	NN
cord-353633-a4pu6rlu	68	22	for	for	IN
cord-353633-a4pu6rlu	68	23	identifying	identify	VBG
cord-353633-a4pu6rlu	68	24	the	the	DT
cord-353633-a4pu6rlu	68	25	patients	patient	NNS
cord-353633-a4pu6rlu	68	26	at	at	IN
cord-353633-a4pu6rlu	68	27	higher	high	JJR
cord-353633-a4pu6rlu	68	28	risk	risk	NN
cord-353633-a4pu6rlu	68	29	for	for	IN
cord-353633-a4pu6rlu	68	30	presenting	present	VBG
cord-353633-a4pu6rlu	68	31	a	a	DT
cord-353633-a4pu6rlu	68	32	more	more	RBR
cord-353633-a4pu6rlu	68	33	aggressive	aggressive	JJ
cord-353633-a4pu6rlu	68	34	course	course	NN
cord-353633-a4pu6rlu	68	35	of	of	IN
cord-353633-a4pu6rlu	68	36	disease	disease	NN
cord-353633-a4pu6rlu	68	37	and/or	and/or	CC
cord-353633-a4pu6rlu	68	38	for	for	IN
cord-353633-a4pu6rlu	68	39	potentially	potentially	RB
cord-353633-a4pu6rlu	68	40	predicting	predict	VBG
cord-353633-a4pu6rlu	68	41	the	the	DT
cord-353633-a4pu6rlu	68	42	response	response	NN
cord-353633-a4pu6rlu	68	43	to	to	IN
cord-353633-a4pu6rlu	68	44	specific	specific	JJ
cord-353633-a4pu6rlu	68	45	treatments	treatment	NNS
cord-353633-a4pu6rlu	68	46	.	.	.
cord-353633-a4pu6rlu	69	1	These	these	DT
cord-353633-a4pu6rlu	69	2	may	may	MD
cord-353633-a4pu6rlu	69	3	justify	justify	VB
cord-353633-a4pu6rlu	69	4	more	more	RBR
cord-353633-a4pu6rlu	69	5	intensive	intensive	JJ
cord-353633-a4pu6rlu	69	6	follow	follow	NN
cord-353633-a4pu6rlu	69	7	-	-	HYPH
cord-353633-a4pu6rlu	69	8	ups	up	NNS
cord-353633-a4pu6rlu	69	9	or	or	CC
cord-353633-a4pu6rlu	69	10	guide	guide	NN
cord-353633-a4pu6rlu	69	11	treatment	treatment	NN
cord-353633-a4pu6rlu	69	12	decisions	decision	NNS
cord-353633-a4pu6rlu	69	13	in	in	IN
cord-353633-a4pu6rlu	69	14	high	high	JJ
cord-353633-a4pu6rlu	69	15	-	-	HYPH
cord-353633-a4pu6rlu	69	16	risk	risk	NN
cord-353633-a4pu6rlu	69	17	populations	population	NNS
cord-353633-a4pu6rlu	69	18	.	.	.
cord-353633-a4pu6rlu	70	1	Sfince	Sfince	NNP
cord-353633-a4pu6rlu	70	2	genomics	genomic	NNS
cord-353633-a4pu6rlu	70	3	are	be	VBP
cord-353633-a4pu6rlu	70	4	not	not	RB
cord-353633-a4pu6rlu	70	5	dynamic	dynamic	JJ
cord-353633-a4pu6rlu	70	6	processes	process	NNS
cord-353633-a4pu6rlu	70	7	and	and	CC
cord-353633-a4pu6rlu	70	8	do	do	VBP
cord-353633-a4pu6rlu	70	9	not	not	RB
cord-353633-a4pu6rlu	70	10	reflect	reflect	VB
cord-353633-a4pu6rlu	70	11	the	the	DT
cord-353633-a4pu6rlu	70	12	effects	effect	NNS
cord-353633-a4pu6rlu	70	13	of	of	IN
cord-353633-a4pu6rlu	70	14	environmental	environmental	JJ
cord-353633-a4pu6rlu	70	15	factors	factor	NNS
cord-353633-a4pu6rlu	70	16	on	on	IN
cord-353633-a4pu6rlu	70	17	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	70	18	,	,	,
cord-353633-a4pu6rlu	70	19	we	-PRON-	PRP
cord-353633-a4pu6rlu	70	20	see	see	VBP
cord-353633-a4pu6rlu	70	21	less	less	JJR
cord-353633-a4pu6rlu	70	22	potentials	potential	NNS
cord-353633-a4pu6rlu	70	23	for	for	IN
cord-353633-a4pu6rlu	70	24	them	-PRON-	PRP
cord-353633-a4pu6rlu	70	25	as	as	IN
cord-353633-a4pu6rlu	70	26	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	70	27	markers	marker	NNS
cord-353633-a4pu6rlu	70	28	and	and	CC
cord-353633-a4pu6rlu	70	29	we	-PRON-	PRP
cord-353633-a4pu6rlu	70	30	expect	expect	VBP
cord-353633-a4pu6rlu	70	31	for	for	IN
cord-353633-a4pu6rlu	70	32	them	-PRON-	PRP
cord-353633-a4pu6rlu	70	33	to	to	TO
cord-353633-a4pu6rlu	70	34	have	have	VB
cord-353633-a4pu6rlu	70	35	only	only	RB
cord-353633-a4pu6rlu	70	36	a	a	DT
cord-353633-a4pu6rlu	70	37	small	small	JJ
cord-353633-a4pu6rlu	70	38	,	,	,
cord-353633-a4pu6rlu	70	39	if	if	IN
cord-353633-a4pu6rlu	70	40	any	any	DT
cord-353633-a4pu6rlu	70	41	,	,	,
cord-353633-a4pu6rlu	70	42	contribution	contribution	NN
cord-353633-a4pu6rlu	70	43	in	in	IN
cord-353633-a4pu6rlu	70	44	non	non	JJ
cord-353633-a4pu6rlu	70	45	-	-	JJ
cord-353633-a4pu6rlu	70	46	invasive	invasive	JJ
cord-353633-a4pu6rlu	70	47	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	70	48	tests	test	NNS
cord-353633-a4pu6rlu	70	49	.	.	.
cord-353633-a4pu6rlu	71	1	Finally	finally	RB
cord-353633-a4pu6rlu	71	2	,	,	,
cord-353633-a4pu6rlu	71	3	due	due	IN
cord-353633-a4pu6rlu	71	4	to	to	IN
cord-353633-a4pu6rlu	71	5	the	the	DT
cord-353633-a4pu6rlu	71	6	technical	technical	JJ
cord-353633-a4pu6rlu	71	7	and	and	CC
cord-353633-a4pu6rlu	71	8	clinical	clinical	JJ
cord-353633-a4pu6rlu	71	9	challenges	challenge	NNS
cord-353633-a4pu6rlu	71	10	related	relate	VBN
cord-353633-a4pu6rlu	71	11	to	to	IN
cord-353633-a4pu6rlu	71	12	geneengineering	geneengineere	VBG
cord-353633-a4pu6rlu	71	13	as	as	RB
cord-353633-a4pu6rlu	71	14	well	well	RB
cord-353633-a4pu6rlu	71	15	as	as	IN
cord-353633-a4pu6rlu	71	16	due	due	IN
cord-353633-a4pu6rlu	71	17	to	to	IN
cord-353633-a4pu6rlu	71	18	the	the	DT
cord-353633-a4pu6rlu	71	19	complex	complex	JJ
cord-353633-a4pu6rlu	71	20	pathophysiology	pathophysiology	NN
cord-353633-a4pu6rlu	71	21	of	of	IN
cord-353633-a4pu6rlu	71	22	the	the	DT
cord-353633-a4pu6rlu	71	23	disease	disease	NN
cord-353633-a4pu6rlu	71	24	,	,	,
cord-353633-a4pu6rlu	71	25	we	-PRON-	PRP
cord-353633-a4pu6rlu	71	26	recognize	recognize	VBP
cord-353633-a4pu6rlu	71	27	at	at	IN
cord-353633-a4pu6rlu	71	28	the	the	DT
cord-353633-a4pu6rlu	71	29	moment	moment	NN
cord-353633-a4pu6rlu	71	30	limited	limit	VBN
cord-353633-a4pu6rlu	71	31	perspectives	perspective	NNS
cord-353633-a4pu6rlu	71	32	in	in	IN
cord-353633-a4pu6rlu	71	33	the	the	DT
cord-353633-a4pu6rlu	71	34	development	development	NN
cord-353633-a4pu6rlu	71	35	of	of	IN
cord-353633-a4pu6rlu	71	36	gene	gene	NN
cord-353633-a4pu6rlu	71	37	therapies	therapy	NNS
cord-353633-a4pu6rlu	71	38	for	for	IN
cord-353633-a4pu6rlu	71	39	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	71	40	.	.	.
cord-353633-a4pu6rlu	72	1	Epigenomics	Epigenomics	NNP
cord-353633-a4pu6rlu	72	2	investigates	investigate	VBZ
cord-353633-a4pu6rlu	72	3	the	the	DT
cord-353633-a4pu6rlu	72	4	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	72	5	modifications	modification	NNS
cord-353633-a4pu6rlu	72	6	on	on	IN
cord-353633-a4pu6rlu	72	7	cellular	cellular	JJ
cord-353633-a4pu6rlu	72	8	genetical	genetical	JJ
cord-353633-a4pu6rlu	72	9	material	material	NN
cord-353633-a4pu6rlu	72	10	.	.	.
cord-353633-a4pu6rlu	73	1	Several	several	JJ
cord-353633-a4pu6rlu	73	2	studies	study	NNS
cord-353633-a4pu6rlu	73	3	have	have	VBP
cord-353633-a4pu6rlu	73	4	assessed	assess	VBN
cord-353633-a4pu6rlu	73	5	the	the	DT
cord-353633-a4pu6rlu	73	6	impact	impact	NN
cord-353633-a4pu6rlu	73	7	of	of	IN
cord-353633-a4pu6rlu	73	8	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	73	9	modifications	modification	NNS
cord-353633-a4pu6rlu	73	10	in	in	IN
cord-353633-a4pu6rlu	73	11	the	the	DT
cord-353633-a4pu6rlu	73	12	development	development	NN
cord-353633-a4pu6rlu	73	13	and	and	CC
cord-353633-a4pu6rlu	73	14	progress	progress	NN
cord-353633-a4pu6rlu	73	15	of	of	IN
cord-353633-a4pu6rlu	73	16	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	73	17	(	(	-LRB-
cord-353633-a4pu6rlu	73	18	Figure	figure	NN
cord-353633-a4pu6rlu	73	19	2	2	CD
cord-353633-a4pu6rlu	73	20	)	)	-RRB-
cord-353633-a4pu6rlu	73	21	as	as	RB
cord-353633-a4pu6rlu	73	22	well	well	RB
cord-353633-a4pu6rlu	73	23	as	as	IN
cord-353633-a4pu6rlu	73	24	in	in	IN
cord-353633-a4pu6rlu	73	25	the	the	DT
cord-353633-a4pu6rlu	73	26	association	association	NN
cord-353633-a4pu6rlu	73	27	of	of	IN
cord-353633-a4pu6rlu	73	28	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	73	29	with	with	IN
cord-353633-a4pu6rlu	73	30	other	other	JJ
cord-353633-a4pu6rlu	73	31	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	73	32	diseases	disease	NNS
cord-353633-a4pu6rlu	73	33	by	by	IN
cord-353633-a4pu6rlu	73	34	focusing	focus	VBG
cord-353633-a4pu6rlu	73	35	on	on	IN
cord-353633-a4pu6rlu	73	36	DNA	dna	NN
cord-353633-a4pu6rlu	73	37	methylation	methylation	NN
cord-353633-a4pu6rlu	73	38	,	,	,
cord-353633-a4pu6rlu	73	39	histone	histone	NN
cord-353633-a4pu6rlu	73	40	modifications	modification	NNS
cord-353633-a4pu6rlu	73	41	and	and	CC
cord-353633-a4pu6rlu	73	42	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	73	43	expression	expression	NN
cord-353633-a4pu6rlu	73	44	profiles	profile	NNS
cord-353633-a4pu6rlu	73	45	that	that	WDT
cord-353633-a4pu6rlu	73	46	can	can	MD
cord-353633-a4pu6rlu	73	47	significantly	significantly	RB
cord-353633-a4pu6rlu	73	48	affect	affect	VB
cord-353633-a4pu6rlu	73	49	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	73	50	activity	activity	NN
cord-353633-a4pu6rlu	73	51	.	.	.
cord-353633-a4pu6rlu	74	1	Significant	significant	JJ
cord-353633-a4pu6rlu	74	2	alterations	alteration	NNS
cord-353633-a4pu6rlu	74	3	in	in	IN
cord-353633-a4pu6rlu	74	4	DNA	dna	NN
cord-353633-a4pu6rlu	74	5	methylation	methylation	NN
cord-353633-a4pu6rlu	74	6	are	be	VBP
cord-353633-a4pu6rlu	74	7	observed	observe	VBN
cord-353633-a4pu6rlu	74	8	when	when	WRB
cord-353633-a4pu6rlu	74	9	moving	move	VBG
cord-353633-a4pu6rlu	74	10	from	from	IN
cord-353633-a4pu6rlu	74	11	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	74	12	to	to	IN
cord-353633-a4pu6rlu	74	13	NASH	NASH	NNP
cord-353633-a4pu6rlu	74	14	and	and	CC
cord-353633-a4pu6rlu	74	15	liver	liver	NN
cord-353633-a4pu6rlu	74	16	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	74	17	[	[	-LRB-
cord-353633-a4pu6rlu	74	18	56	56	CD
cord-353633-a4pu6rlu	74	19	]	]	-RRB-
cord-353633-a4pu6rlu	74	20	[	[	-LRB-
cord-353633-a4pu6rlu	74	21	57	57	CD
cord-353633-a4pu6rlu	74	22	]	]	-RRB-
cord-353633-a4pu6rlu	74	23	[	[	-LRB-
cord-353633-a4pu6rlu	74	24	58	58	CD
cord-353633-a4pu6rlu	74	25	]	]	-RRB-
cord-353633-a4pu6rlu	74	26	.	.	.
cord-353633-a4pu6rlu	75	1	These	these	DT
cord-353633-a4pu6rlu	75	2	changes	change	NNS
cord-353633-a4pu6rlu	75	3	include	include	VBP
cord-353633-a4pu6rlu	75	4	alterations	alteration	NNS
cord-353633-a4pu6rlu	75	5	J	J	NNP
cord-353633-a4pu6rlu	75	6	o	o	NN
cord-353633-a4pu6rlu	75	7	u	u	NN
cord-353633-a4pu6rlu	75	8	r	r	NN
cord-353633-a4pu6rlu	75	9	n	n	NN
cord-353633-a4pu6rlu	75	10	a	a	DT
cord-353633-a4pu6rlu	75	11	l	l	NN
cord-353633-a4pu6rlu	75	12	P	p	NN
cord-353633-a4pu6rlu	75	13	r	r	NN
cord-353633-a4pu6rlu	75	14	e	e	NN
cord-353633-a4pu6rlu	75	15	-p	-p	NN
cord-353633-a4pu6rlu	76	1	r	r	NNP
cord-353633-a4pu6rlu	76	2	o	o	NN
cord-353633-a4pu6rlu	76	3	o	o	NN
cord-353633-a4pu6rlu	76	4	f	f	NN
cord-353633-a4pu6rlu	76	5	in	in	IN
cord-353633-a4pu6rlu	76	6	DNA	dna	NN
cord-353633-a4pu6rlu	76	7	methylation	methylation	NN
cord-353633-a4pu6rlu	76	8	that	that	WDT
cord-353633-a4pu6rlu	76	9	affect	affect	VBP
cord-353633-a4pu6rlu	76	10	the	the	DT
cord-353633-a4pu6rlu	76	11	expression	expression	NN
cord-353633-a4pu6rlu	76	12	of	of	IN
cord-353633-a4pu6rlu	76	13	genes	gene	NNS
cord-353633-a4pu6rlu	76	14	involved	involve	VBN
cord-353633-a4pu6rlu	76	15	in	in	IN
cord-353633-a4pu6rlu	76	16	glucose	glucose	NN
cord-353633-a4pu6rlu	76	17	,	,	,
cord-353633-a4pu6rlu	76	18	lipid	lipid	NN
cord-353633-a4pu6rlu	76	19	or	or	CC
cord-353633-a4pu6rlu	76	20	acetyl	acetyl	NN
cord-353633-a4pu6rlu	76	21	-	-	HYPH
cord-353633-a4pu6rlu	76	22	coenzyme	coenzyme	NNS
cord-353633-a4pu6rlu	76	23	A	A	NNP
cord-353633-a4pu6rlu	76	24	(	(	-LRB-
cord-353633-a4pu6rlu	76	25	CoA	coa	NN
cord-353633-a4pu6rlu	76	26	)	)	-RRB-
cord-353633-a4pu6rlu	76	27	metabolism	metabolism	NN
cord-353633-a4pu6rlu	76	28	(	(	-LRB-
cord-353633-a4pu6rlu	76	29	PC	pc	NN
cord-353633-a4pu6rlu	76	30	,	,	,
cord-353633-a4pu6rlu	76	31	PLCG1	plcg1	NN
cord-353633-a4pu6rlu	76	32	,	,	,
cord-353633-a4pu6rlu	76	33	ACLY	ACLY	NNP
cord-353633-a4pu6rlu	76	34	)	)	-RRB-
cord-353633-a4pu6rlu	77	1	[	[	-LRB-
cord-353633-a4pu6rlu	77	2	57	57	CD
cord-353633-a4pu6rlu	77	3	]	]	-RRB-
cord-353633-a4pu6rlu	77	4	,	,	,
cord-353633-a4pu6rlu	77	5	insulin	insulin	NN
cord-353633-a4pu6rlu	77	6	-	-	HYPH
cord-353633-a4pu6rlu	77	7	like	like	JJ
cord-353633-a4pu6rlu	77	8	signaling	signaling	NN
cord-353633-a4pu6rlu	77	9	(	(	-LRB-
cord-353633-a4pu6rlu	77	10	e.g.	e.g.	RB
cord-353633-a4pu6rlu	77	11	IGF-1	IGF-1	NNP
cord-353633-a4pu6rlu	77	12	,	,	,
cord-353633-a4pu6rlu	77	13	IGFBP2	igfbp2	NN
cord-353633-a4pu6rlu	77	14	)	)	-RRB-
cord-353633-a4pu6rlu	77	15	and	and	CC
cord-353633-a4pu6rlu	77	16	mitochondrial	mitochondrial	NN
cord-353633-a4pu6rlu	77	17	function	function	NN
cord-353633-a4pu6rlu	77	18	(	(	-LRB-
cord-353633-a4pu6rlu	78	1	NADH	NADH	NNP
cord-353633-a4pu6rlu	78	2	dehydrogenase	dehydrogenase	NNP
cord-353633-a4pu6rlu	78	3	6	6	CD
cord-353633-a4pu6rlu	78	4	)	)	-RRB-
cord-353633-a4pu6rlu	79	1	[	[	-LRB-
cord-353633-a4pu6rlu	79	2	59	59	CD
cord-353633-a4pu6rlu	79	3	]	]	-RRB-
cord-353633-a4pu6rlu	79	4	.	.	.
cord-353633-a4pu6rlu	80	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	80	2	,	,	,
cord-353633-a4pu6rlu	80	3	given	give	VBN
cord-353633-a4pu6rlu	80	4	that	that	IN
cord-353633-a4pu6rlu	80	5	a	a	DT
cord-353633-a4pu6rlu	80	6	specific	specific	JJ
cord-353633-a4pu6rlu	80	7	DNA	dna	NN
cord-353633-a4pu6rlu	80	8	methylation	methylation	NN
cord-353633-a4pu6rlu	80	9	signature	signature	NN
cord-353633-a4pu6rlu	80	10	develops	develop	VBZ
cord-353633-a4pu6rlu	80	11	with	with	IN
cord-353633-a4pu6rlu	80	12	increasing	increase	VBG
cord-353633-a4pu6rlu	80	13	age	age	NN
cord-353633-a4pu6rlu	80	14	in	in	IN
cord-353633-a4pu6rlu	80	15	humans	human	NNS
cord-353633-a4pu6rlu	80	16	,	,	,
cord-353633-a4pu6rlu	80	17	NASH	NASH	NNP
cord-353633-a4pu6rlu	80	18	seems	seem	VBZ
cord-353633-a4pu6rlu	80	19	to	to	TO
cord-353633-a4pu6rlu	80	20	accelerate	accelerate	VB
cord-353633-a4pu6rlu	80	21	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	80	22	age	age	NN
cord-353633-a4pu6rlu	80	23	by	by	IN
cord-353633-a4pu6rlu	80	24	promoting	promote	VBG
cord-353633-a4pu6rlu	80	25	changes	change	NNS
cord-353633-a4pu6rlu	80	26	in	in	IN
cord-353633-a4pu6rlu	80	27	methylation	methylation	NN
cord-353633-a4pu6rlu	80	28	that	that	WDT
cord-353633-a4pu6rlu	80	29	are	be	VBP
cord-353633-a4pu6rlu	80	30	associated	associate	VBN
cord-353633-a4pu6rlu	80	31	with	with	IN
cord-353633-a4pu6rlu	80	32	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	80	33	collagen	collagen	NN
cord-353633-a4pu6rlu	80	34	content	content	NN
cord-353633-a4pu6rlu	80	35	[	[	-LRB-
cord-353633-a4pu6rlu	80	36	60	60	CD
cord-353633-a4pu6rlu	80	37	]	]	-RRB-
cord-353633-a4pu6rlu	80	38	.	.	.
cord-353633-a4pu6rlu	81	1	An	an	DT
cord-353633-a4pu6rlu	81	2	untargeted	untargeted	JJ
cord-353633-a4pu6rlu	81	3	evaluation	evaluation	NN
cord-353633-a4pu6rlu	81	4	of	of	IN
cord-353633-a4pu6rlu	81	5	DNA	dna	NN
cord-353633-a4pu6rlu	81	6	methylation	methylation	NN
cord-353633-a4pu6rlu	81	7	in	in	IN
cord-353633-a4pu6rlu	81	8	liver	liver	NN
cord-353633-a4pu6rlu	81	9	tissues	tissue	NNS
cord-353633-a4pu6rlu	81	10	of	of	IN
cord-353633-a4pu6rlu	81	11	patients	patient	NNS
cord-353633-a4pu6rlu	81	12	with	with	IN
cord-353633-a4pu6rlu	81	13	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	81	14	identified	identify	VBD
cord-353633-a4pu6rlu	81	15	almost	almost	RB
cord-353633-a4pu6rlu	81	16	70,000	70,000	CD
cord-353633-a4pu6rlu	81	17	CpG	CpG	NNP
cord-353633-a4pu6rlu	81	18	sites	site	NNS
cord-353633-a4pu6rlu	81	19	that	that	WDT
cord-353633-a4pu6rlu	81	20	were	be	VBD
cord-353633-a4pu6rlu	81	21	differentially	differentially	RB
cord-353633-a4pu6rlu	81	22	methylated	methylate	VBN
cord-353633-a4pu6rlu	81	23	in	in	IN
cord-353633-a4pu6rlu	81	24	patients	patient	NNS
cord-353633-a4pu6rlu	81	25	with	with	IN
cord-353633-a4pu6rlu	81	26	advanced	advanced	JJ
cord-353633-a4pu6rlu	81	27	liver	liver	NN
cord-353633-a4pu6rlu	81	28	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	81	29	(	(	-LRB-
cord-353633-a4pu6rlu	81	30	F3-F4	F3-F4	NNP
cord-353633-a4pu6rlu	81	31	)	)	-RRB-
cord-353633-a4pu6rlu	81	32	compared	compare	VBN
cord-353633-a4pu6rlu	81	33	to	to	IN
cord-353633-a4pu6rlu	81	34	those	those	DT
cord-353633-a4pu6rlu	81	35	with	with	IN
cord-353633-a4pu6rlu	81	36	no	no	DT
cord-353633-a4pu6rlu	81	37	or	or	CC
cord-353633-a4pu6rlu	81	38	mild	mild	JJ
cord-353633-a4pu6rlu	81	39	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	81	40	(	(	-LRB-
cord-353633-a4pu6rlu	81	41	F0-F1	F0-F1	NNP
cord-353633-a4pu6rlu	81	42	)	)	-RRB-
cord-353633-a4pu6rlu	81	43	.	.	.
cord-353633-a4pu6rlu	82	1	76	76	CD
cord-353633-a4pu6rlu	82	2	%	%	NN
cord-353633-a4pu6rlu	82	3	of	of	IN
cord-353633-a4pu6rlu	82	4	these	these	DT
cord-353633-a4pu6rlu	82	5	sites	site	NNS
cord-353633-a4pu6rlu	82	6	were	be	VBD
cord-353633-a4pu6rlu	82	7	hypomethylated	hypomethylate	VBN
cord-353633-a4pu6rlu	82	8	and	and	CC
cord-353633-a4pu6rlu	82	9	24	24	CD
cord-353633-a4pu6rlu	82	10	%	%	NN
cord-353633-a4pu6rlu	82	11	were	be	VBD
cord-353633-a4pu6rlu	82	12	hypermethylated	hypermethylate	VBN
cord-353633-a4pu6rlu	82	13	in	in	IN
cord-353633-a4pu6rlu	82	14	advanced	advanced	JJ
cord-353633-a4pu6rlu	82	15	liver	liver	NN
cord-353633-a4pu6rlu	82	16	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	82	17	in	in	IN
cord-353633-a4pu6rlu	82	18	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	82	19	,	,	,
cord-353633-a4pu6rlu	82	20	whereas	whereas	IN
cord-353633-a4pu6rlu	82	21	7	7	CD
cord-353633-a4pu6rlu	82	22	%	%	NN
cord-353633-a4pu6rlu	82	23	of	of	IN
cord-353633-a4pu6rlu	82	24	the	the	DT
cord-353633-a4pu6rlu	82	25	reported	report	VBN
cord-353633-a4pu6rlu	82	26	methylations	methylation	NNS
cord-353633-a4pu6rlu	82	27	correlated	correlate	VBN
cord-353633-a4pu6rlu	82	28	with	with	IN
cord-353633-a4pu6rlu	82	29	gene	gene	NN
cord-353633-a4pu6rlu	82	30	expression	expression	NN
cord-353633-a4pu6rlu	82	31	levels	level	NNS
cord-353633-a4pu6rlu	82	32	.	.	.
cord-353633-a4pu6rlu	83	1	The	the	DT
cord-353633-a4pu6rlu	83	2	hypomethylation	hypomethylation	NN
cord-353633-a4pu6rlu	83	3	was	be	VBD
cord-353633-a4pu6rlu	83	4	associated	associate	VBN
cord-353633-a4pu6rlu	83	5	with	with	IN
cord-353633-a4pu6rlu	83	6	higher	high	JJR
cord-353633-a4pu6rlu	83	7	expression	expression	NN
cord-353633-a4pu6rlu	83	8	of	of	IN
cord-353633-a4pu6rlu	83	9	genes	gene	NNS
cord-353633-a4pu6rlu	83	10	related	relate	VBN
cord-353633-a4pu6rlu	83	11	to	to	IN
cord-353633-a4pu6rlu	83	12	tissue	tissue	NN
cord-353633-a4pu6rlu	83	13	repair	repair	NN
cord-353633-a4pu6rlu	83	14	,	,	,
cord-353633-a4pu6rlu	83	15	liver	liver	NN
cord-353633-a4pu6rlu	83	16	inflammation	inflammation	NN
cord-353633-a4pu6rlu	83	17	,	,	,
cord-353633-a4pu6rlu	83	18	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	83	19	and	and	CC
cord-353633-a4pu6rlu	83	20	carcinogenesis	carcinogenesis	NN
cord-353633-a4pu6rlu	83	21	(	(	-LRB-
cord-353633-a4pu6rlu	83	22	e.g.	e.g.	RB
cord-353633-a4pu6rlu	83	23	FGFR2	fgfr2	NN
cord-353633-a4pu6rlu	83	24	,	,	,
cord-353633-a4pu6rlu	83	25	COL1A1	COL1A1	NNP
cord-353633-a4pu6rlu	83	26	,	,	,
cord-353633-a4pu6rlu	83	27	CASP1	CASP1	NNP
cord-353633-a4pu6rlu	83	28	,	,	,
cord-353633-a4pu6rlu	83	29	CCR7	CCR7	NNP
cord-353633-a4pu6rlu	83	30	,	,	,
cord-353633-a4pu6rlu	83	31	CCL5	CCL5	NNP
cord-353633-a4pu6rlu	83	32	)	)	-RRB-
cord-353633-a4pu6rlu	83	33	whereas	whereas	IN
cord-353633-a4pu6rlu	83	34	the	the	DT
cord-353633-a4pu6rlu	83	35	hypermethylation	hypermethylation	NN
cord-353633-a4pu6rlu	83	36	with	with	IN
cord-353633-a4pu6rlu	83	37	lower	low	JJR
cord-353633-a4pu6rlu	83	38	expression	expression	NN
cord-353633-a4pu6rlu	83	39	of	of	IN
cord-353633-a4pu6rlu	83	40	genes	gene	NNS
cord-353633-a4pu6rlu	83	41	involved	involve	VBN
cord-353633-a4pu6rlu	83	42	in	in	IN
cord-353633-a4pu6rlu	83	43	lipid	lipid	NN
cord-353633-a4pu6rlu	83	44	and	and	CC
cord-353633-a4pu6rlu	83	45	aminoacid	aminoacid	JJ
cord-353633-a4pu6rlu	83	46	metabolism	metabolism	NN
cord-353633-a4pu6rlu	83	47	[	[	-LRB-
cord-353633-a4pu6rlu	83	48	56	56	CD
cord-353633-a4pu6rlu	83	49	,	,	,
cord-353633-a4pu6rlu	83	50	61	61	CD
cord-353633-a4pu6rlu	83	51	]	]	-RRB-
cord-353633-a4pu6rlu	83	52	.	.	.
cord-353633-a4pu6rlu	84	1	These	these	DT
cord-353633-a4pu6rlu	84	2	findings	finding	NNS
cord-353633-a4pu6rlu	84	3	were	be	VBD
cord-353633-a4pu6rlu	84	4	also	also	RB
cord-353633-a4pu6rlu	84	5	replicated	replicate	VBN
cord-353633-a4pu6rlu	84	6	in	in	IN
cord-353633-a4pu6rlu	84	7	other	other	JJ
cord-353633-a4pu6rlu	84	8	studies	study	NNS
cord-353633-a4pu6rlu	84	9	[	[	-LRB-
cord-353633-a4pu6rlu	84	10	62	62	CD
cord-353633-a4pu6rlu	84	11	]	]	-RRB-
cord-353633-a4pu6rlu	84	12	.	.	.
cord-353633-a4pu6rlu	85	1	DNA	dna	NN
cord-353633-a4pu6rlu	85	2	methylation	methylation	NN
cord-353633-a4pu6rlu	85	3	seems	seem	VBZ
cord-353633-a4pu6rlu	85	4	to	to	TO
cord-353633-a4pu6rlu	85	5	be	be	VB
cord-353633-a4pu6rlu	85	6	particularly	particularly	RB
cord-353633-a4pu6rlu	85	7	involved	involve	VBN
cord-353633-a4pu6rlu	85	8	in	in	IN
cord-353633-a4pu6rlu	85	9	the	the	DT
cord-353633-a4pu6rlu	85	10	activation	activation	NN
cord-353633-a4pu6rlu	85	11	of	of	IN
cord-353633-a4pu6rlu	85	12	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	85	13	stellate	stellate	JJ
cord-353633-a4pu6rlu	85	14	cells	cell	NNS
cord-353633-a4pu6rlu	85	15	and	and	CC
cord-353633-a4pu6rlu	85	16	their	-PRON-	PRP$
cord-353633-a4pu6rlu	85	17	differentiation	differentiation	NN
cord-353633-a4pu6rlu	85	18	to	to	TO
cord-353633-a4pu6rlu	85	19	myofibroblast	myofibroblast	VB
cord-353633-a4pu6rlu	85	20	that	that	WDT
cord-353633-a4pu6rlu	85	21	are	be	VBP
cord-353633-a4pu6rlu	85	22	crucial	crucial	JJ
cord-353633-a4pu6rlu	85	23	procedures	procedure	NNS
cord-353633-a4pu6rlu	85	24	for	for	IN
cord-353633-a4pu6rlu	85	25	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	85	26	fibrogenesis	fibrogenesis	NN
cord-353633-a4pu6rlu	85	27	[	[	-LRB-
cord-353633-a4pu6rlu	85	28	63	63	CD
cord-353633-a4pu6rlu	85	29	,	,	,
cord-353633-a4pu6rlu	85	30	64	64	CD
cord-353633-a4pu6rlu	85	31	]	]	-RRB-
cord-353633-a4pu6rlu	85	32	.	.	.
cord-353633-a4pu6rlu	86	1	Changes	change	NNS
cord-353633-a4pu6rlu	86	2	in	in	IN
cord-353633-a4pu6rlu	86	3	methylation	methylation	NN
cord-353633-a4pu6rlu	86	4	of	of	IN
cord-353633-a4pu6rlu	86	5	specific	specific	JJ
cord-353633-a4pu6rlu	86	6	genes	gene	NNS
cord-353633-a4pu6rlu	86	7	have	have	VBP
cord-353633-a4pu6rlu	86	8	been	be	VBN
cord-353633-a4pu6rlu	86	9	linked	link	VBN
cord-353633-a4pu6rlu	86	10	with	with	IN
cord-353633-a4pu6rlu	86	11	these	these	DT
cord-353633-a4pu6rlu	86	12	processes	process	NNS
cord-353633-a4pu6rlu	86	13	.	.	.
cord-353633-a4pu6rlu	87	1	Genes	gene	NNS
cord-353633-a4pu6rlu	87	2	promoting	promote	VBG
cord-353633-a4pu6rlu	87	3	fibrogenesis	fibrogenesis	NN
cord-353633-a4pu6rlu	87	4	such	such	JJ
cord-353633-a4pu6rlu	87	5	as	as	IN
cord-353633-a4pu6rlu	87	6	TGFβ1	TGFβ1	NNP
cord-353633-a4pu6rlu	87	7	and	and	CC
cord-353633-a4pu6rlu	87	8	PDGFα	PDGFα	NNS
cord-353633-a4pu6rlu	87	9	are	be	VBP
cord-353633-a4pu6rlu	87	10	hypomethylated	hypomethylate	VBN
cord-353633-a4pu6rlu	87	11	and	and	CC
cord-353633-a4pu6rlu	87	12	thus	thus	RB
cord-353633-a4pu6rlu	87	13	highly	highly	RB
cord-353633-a4pu6rlu	87	14	expressed	express	VBN
cord-353633-a4pu6rlu	88	1	whereas	whereas	IN
cord-353633-a4pu6rlu	88	2	genes	gene	NNS
cord-353633-a4pu6rlu	88	3	inhibiting	inhibit	VBG
cord-353633-a4pu6rlu	88	4	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	88	5	stellate	stellate	JJ
cord-353633-a4pu6rlu	88	6	cells	cell	NNS
cord-353633-a4pu6rlu	88	7	activation	activation	VBP
cord-353633-a4pu6rlu	88	8	such	such	JJ
cord-353633-a4pu6rlu	88	9	as	as	IN
cord-353633-a4pu6rlu	88	10	the	the	DT
cord-353633-a4pu6rlu	88	11	PPARα	PPARα	NNS
cord-353633-a4pu6rlu	88	12	,	,	,
cord-353633-a4pu6rlu	88	13	PPARδ	PPARδ	NNS
cord-353633-a4pu6rlu	88	14	and	and	CC
cord-353633-a4pu6rlu	88	15	PPARγ	PPARγ	NNS
cord-353633-a4pu6rlu	88	16	are	be	VBP
cord-353633-a4pu6rlu	88	17	hypermethylated	hypermethylate	VBN
cord-353633-a4pu6rlu	88	18	and	and	CC
cord-353633-a4pu6rlu	88	19	J	J	NNP
cord-353633-a4pu6rlu	88	20	o	o	NN
cord-353633-a4pu6rlu	88	21	u	u	NN
cord-353633-a4pu6rlu	88	22	r	r	NN
cord-353633-a4pu6rlu	88	23	n	n	NN
cord-353633-a4pu6rlu	88	24	a	a	NN
cord-353633-a4pu6rlu	89	1	l	l	NN
cord-353633-a4pu6rlu	89	2	P	p	NN
cord-353633-a4pu6rlu	89	3	r	r	NN
cord-353633-a4pu6rlu	89	4	e	e	NN
cord-353633-a4pu6rlu	89	5	-p	-p	NN
cord-353633-a4pu6rlu	89	6	r	r	NN
cord-353633-a4pu6rlu	89	7	o	o	NN
cord-353633-a4pu6rlu	89	8	o	o	NN
cord-353633-a4pu6rlu	89	9	f	f	NN
cord-353633-a4pu6rlu	89	10	18	18	CD
cord-353633-a4pu6rlu	89	11	thus	thus	RB
cord-353633-a4pu6rlu	89	12	lower	lower	RBR
cord-353633-a4pu6rlu	89	13	expressed	express	VBN
cord-353633-a4pu6rlu	89	14	in	in	IN
cord-353633-a4pu6rlu	89	15	the	the	DT
cord-353633-a4pu6rlu	89	16	liver	liver	NN
cord-353633-a4pu6rlu	89	17	of	of	IN
cord-353633-a4pu6rlu	89	18	patients	patient	NNS
cord-353633-a4pu6rlu	89	19	with	with	IN
cord-353633-a4pu6rlu	89	20	advanced	advanced	JJ
cord-353633-a4pu6rlu	89	21	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	89	22	compared	compare	VBN
cord-353633-a4pu6rlu	89	23	to	to	IN
cord-353633-a4pu6rlu	89	24	the	the	DT
cord-353633-a4pu6rlu	89	25	ones	one	NNS
cord-353633-a4pu6rlu	89	26	with	with	IN
cord-353633-a4pu6rlu	89	27	mild	mild	JJ
cord-353633-a4pu6rlu	89	28	disease	disease	NN
cord-353633-a4pu6rlu	89	29	[	[	-LRB-
cord-353633-a4pu6rlu	89	30	65	65	CD
cord-353633-a4pu6rlu	89	31	,	,	,
cord-353633-a4pu6rlu	89	32	66	66	CD
cord-353633-a4pu6rlu	89	33	]	]	-RRB-
cord-353633-a4pu6rlu	89	34	.	.	.
cord-353633-a4pu6rlu	90	1	Apart	apart	RB
cord-353633-a4pu6rlu	90	2	from	from	IN
cord-353633-a4pu6rlu	90	3	their	-PRON-	PRP$
cord-353633-a4pu6rlu	90	4	involvement	involvement	NN
cord-353633-a4pu6rlu	90	5	in	in	IN
cord-353633-a4pu6rlu	90	6	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	90	7	development	development	NN
cord-353633-a4pu6rlu	90	8	and	and	CC
cord-353633-a4pu6rlu	90	9	progress	progress	NN
cord-353633-a4pu6rlu	90	10	,	,	,
cord-353633-a4pu6rlu	90	11	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	90	12	alterations	alteration	NNS
cord-353633-a4pu6rlu	90	13	in	in	IN
cord-353633-a4pu6rlu	90	14	DNA	dna	NN
cord-353633-a4pu6rlu	90	15	methylation	methylation	NN
cord-353633-a4pu6rlu	90	16	may	may	MD
cord-353633-a4pu6rlu	90	17	be	be	VB
cord-353633-a4pu6rlu	90	18	associated	associate	VBN
cord-353633-a4pu6rlu	90	19	with	with	IN
cord-353633-a4pu6rlu	90	20	systemic	systemic	JJ
cord-353633-a4pu6rlu	90	21	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	90	22	outcomes	outcome	NNS
cord-353633-a4pu6rlu	90	23	.	.	.
cord-353633-a4pu6rlu	91	1	Specifically	specifically	RB
cord-353633-a4pu6rlu	91	2	,	,	,
cord-353633-a4pu6rlu	91	3	a	a	DT
cord-353633-a4pu6rlu	91	4	case	case	NN
cord-353633-a4pu6rlu	91	5	-	-	HYPH
cord-353633-a4pu6rlu	91	6	control	control	NN
cord-353633-a4pu6rlu	91	7	study	study	NN
cord-353633-a4pu6rlu	91	8	in	in	IN
cord-353633-a4pu6rlu	91	9	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	91	10	patients	patient	NNS
cord-353633-a4pu6rlu	91	11	has	have	VBZ
cord-353633-a4pu6rlu	91	12	shown	show	VBN
cord-353633-a4pu6rlu	91	13	that	that	IN
cord-353633-a4pu6rlu	91	14	increased	increase	VBN
cord-353633-a4pu6rlu	91	15	methylation	methylation	NN
cord-353633-a4pu6rlu	91	16	in	in	IN
cord-353633-a4pu6rlu	91	17	specific	specific	JJ
cord-353633-a4pu6rlu	91	18	sites	site	NNS
cord-353633-a4pu6rlu	91	19	of	of	IN
cord-353633-a4pu6rlu	91	20	the	the	DT
cord-353633-a4pu6rlu	91	21	promoter	promoter	NN
cord-353633-a4pu6rlu	91	22	of	of	IN
cord-353633-a4pu6rlu	91	23	the	the	DT
cord-353633-a4pu6rlu	91	24	PPARGC1A	PPARGC1A	NNP
cord-353633-a4pu6rlu	91	25	,	,	,
cord-353633-a4pu6rlu	91	26	which	which	WDT
cord-353633-a4pu6rlu	91	27	encodes	encode	VBZ
cord-353633-a4pu6rlu	91	28	the	the	DT
cord-353633-a4pu6rlu	91	29	major	major	JJ
cord-353633-a4pu6rlu	91	30	regulator	regulator	NN
cord-353633-a4pu6rlu	91	31	of	of	IN
cord-353633-a4pu6rlu	91	32	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	91	33	biogenesis	biogenesis	NN
cord-353633-a4pu6rlu	91	34	,	,	,
cord-353633-a4pu6rlu	91	35	is	be	VBZ
cord-353633-a4pu6rlu	91	36	associated	associate	VBN
cord-353633-a4pu6rlu	91	37	with	with	IN
cord-353633-a4pu6rlu	91	38	lower	low	JJR
cord-353633-a4pu6rlu	91	39	mRNA	mRNA	NNP
cord-353633-a4pu6rlu	91	40	expression	expression	NN
cord-353633-a4pu6rlu	91	41	of	of	IN
cord-353633-a4pu6rlu	91	42	PPARGC1A	ppargc1a	NN
cord-353633-a4pu6rlu	91	43	in	in	IN
cord-353633-a4pu6rlu	91	44	the	the	DT
cord-353633-a4pu6rlu	91	45	liver	liver	NN
cord-353633-a4pu6rlu	91	46	,	,	,
cord-353633-a4pu6rlu	91	47	lower	low	JJR
cord-353633-a4pu6rlu	91	48	ratio	ratio	NN
cord-353633-a4pu6rlu	91	49	of	of	IN
cord-353633-a4pu6rlu	91	50	mitochondrial	mitochondrial	NN
cord-353633-a4pu6rlu	91	51	to	to	IN
cord-353633-a4pu6rlu	91	52	nuclear	nuclear	JJ
cord-353633-a4pu6rlu	91	53	DNA	dna	NN
cord-353633-a4pu6rlu	91	54	and	and	CC
cord-353633-a4pu6rlu	91	55	increased	increase	VBN
cord-353633-a4pu6rlu	91	56	insulin	insulin	NN
cord-353633-a4pu6rlu	91	57	resistance	resistance	NN
cord-353633-a4pu6rlu	91	58	,	,	,
cord-353633-a4pu6rlu	91	59	thus	thus	RB
cord-353633-a4pu6rlu	91	60	linking	link	VBG
cord-353633-a4pu6rlu	91	61	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	91	62	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	91	63	dysfunction	dysfunction	NN
cord-353633-a4pu6rlu	91	64	of	of	IN
cord-353633-a4pu6rlu	91	65	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	91	66	with	with	IN
cord-353633-a4pu6rlu	91	67	peripheral	peripheral	JJ
cord-353633-a4pu6rlu	91	68	insulin	insulin	NN
cord-353633-a4pu6rlu	91	69	resistance	resistance	NN
cord-353633-a4pu6rlu	91	70	[	[	-LRB-
cord-353633-a4pu6rlu	91	71	67	67	CD
cord-353633-a4pu6rlu	91	72	]	]	-RRB-
cord-353633-a4pu6rlu	91	73	.	.	.
cord-353633-a4pu6rlu	92	1	In	in	IN
cord-353633-a4pu6rlu	92	2	agreement	agreement	NN
cord-353633-a4pu6rlu	92	3	with	with	IN
cord-353633-a4pu6rlu	92	4	the	the	DT
cord-353633-a4pu6rlu	92	5	above	above	JJ
cord-353633-a4pu6rlu	92	6	finding	finding	NN
cord-353633-a4pu6rlu	92	7	,	,	,
cord-353633-a4pu6rlu	92	8	a	a	DT
cord-353633-a4pu6rlu	92	9	study	study	NN
cord-353633-a4pu6rlu	92	10	following	follow	VBG
cord-353633-a4pu6rlu	92	11	untargeted	untargeted	JJ
cord-353633-a4pu6rlu	92	12	procedures	procedure	NNS
cord-353633-a4pu6rlu	92	13	has	have	VBZ
cord-353633-a4pu6rlu	92	14	identified	identify	VBN
cord-353633-a4pu6rlu	92	15	30	30	CD
cord-353633-a4pu6rlu	92	16	methylations	methylation	NNS
cord-353633-a4pu6rlu	92	17	that	that	WDT
cord-353633-a4pu6rlu	92	18	are	be	VBP
cord-353633-a4pu6rlu	92	19	affecting	affect	VBG
cord-353633-a4pu6rlu	92	20	mRNA	mrna	NN
cord-353633-a4pu6rlu	92	21	expression	expression	NN
cord-353633-a4pu6rlu	92	22	of	of	IN
cord-353633-a4pu6rlu	92	23	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	92	24	genes	gene	NNS
cord-353633-a4pu6rlu	92	25	involved	involve	VBN
cord-353633-a4pu6rlu	92	26	in	in	IN
cord-353633-a4pu6rlu	92	27	insulin	insulin	NN
cord-353633-a4pu6rlu	92	28	signaling	signaling	NN
cord-353633-a4pu6rlu	92	29	that	that	WDT
cord-353633-a4pu6rlu	92	30	are	be	VBP
cord-353633-a4pu6rlu	92	31	also	also	RB
cord-353633-a4pu6rlu	92	32	highly	highly	RB
cord-353633-a4pu6rlu	92	33	correlated	correlate	VBN
cord-353633-a4pu6rlu	92	34	with	with	IN
cord-353633-a4pu6rlu	92	35	fasting	fast	VBG
cord-353633-a4pu6rlu	92	36	insulin	insulin	NN
cord-353633-a4pu6rlu	92	37	independently	independently	RB
cord-353633-a4pu6rlu	92	38	of	of	IN
cord-353633-a4pu6rlu	92	39	the	the	DT
cord-353633-a4pu6rlu	92	40	presence	presence	NN
cord-353633-a4pu6rlu	92	41	of	of	IN
cord-353633-a4pu6rlu	92	42	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	92	43	,	,	,
cord-353633-a4pu6rlu	92	44	thus	thus	RB
cord-353633-a4pu6rlu	92	45	providing	provide	VBG
cord-353633-a4pu6rlu	92	46	further	further	JJ
cord-353633-a4pu6rlu	92	47	evidence	evidence	NN
cord-353633-a4pu6rlu	92	48	for	for	IN
cord-353633-a4pu6rlu	92	49	the	the	DT
cord-353633-a4pu6rlu	92	50	relation	relation	NN
cord-353633-a4pu6rlu	92	51	of	of	IN
cord-353633-a4pu6rlu	92	52	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	92	53	DNA	dna	NN
cord-353633-a4pu6rlu	92	54	methylation	methylation	NN
cord-353633-a4pu6rlu	92	55	with	with	IN
cord-353633-a4pu6rlu	92	56	insulin	insulin	NN
cord-353633-a4pu6rlu	92	57	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	92	58	[	[	-LRB-
cord-353633-a4pu6rlu	92	59	58	58	CD
cord-353633-a4pu6rlu	92	60	]	]	-RRB-
cord-353633-a4pu6rlu	92	61	.	.	.
cord-353633-a4pu6rlu	93	1	Finally	finally	RB
cord-353633-a4pu6rlu	93	2	,	,	,
cord-353633-a4pu6rlu	93	3	a	a	DT
cord-353633-a4pu6rlu	93	4	recent	recent	JJ
cord-353633-a4pu6rlu	93	5	study	study	NN
cord-353633-a4pu6rlu	93	6	focused	focus	VBD
cord-353633-a4pu6rlu	93	7	on	on	IN
cord-353633-a4pu6rlu	93	8	the	the	DT
cord-353633-a4pu6rlu	93	9	identification	identification	NN
cord-353633-a4pu6rlu	93	10	of	of	IN
cord-353633-a4pu6rlu	93	11	differentially	differentially	RB
cord-353633-a4pu6rlu	93	12	methylated	methylate	VBN
cord-353633-a4pu6rlu	93	13	regions	region	NNS
cord-353633-a4pu6rlu	93	14	that	that	WDT
cord-353633-a4pu6rlu	93	15	form	form	VBP
cord-353633-a4pu6rlu	93	16	networks	network	NNS
cord-353633-a4pu6rlu	93	17	which	which	WDT
cord-353633-a4pu6rlu	93	18	are	be	VBP
cord-353633-a4pu6rlu	93	19	associated	associate	VBN
cord-353633-a4pu6rlu	93	20	with	with	IN
cord-353633-a4pu6rlu	93	21	the	the	DT
cord-353633-a4pu6rlu	93	22	progression	progression	NN
cord-353633-a4pu6rlu	93	23	of	of	IN
cord-353633-a4pu6rlu	93	24	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	93	25	.	.	.
cord-353633-a4pu6rlu	94	1	They	-PRON-	PRP
cord-353633-a4pu6rlu	94	2	identified	identify	VBD
cord-353633-a4pu6rlu	94	3	two	two	CD
cord-353633-a4pu6rlu	94	4	important	important	JJ
cord-353633-a4pu6rlu	94	5	networks	network	NNS
cord-353633-a4pu6rlu	94	6	,	,	,
cord-353633-a4pu6rlu	94	7	one	one	CD
cord-353633-a4pu6rlu	94	8	that	that	WDT
cord-353633-a4pu6rlu	94	9	included	include	VBD
cord-353633-a4pu6rlu	94	10	genes	gene	NNS
cord-353633-a4pu6rlu	94	11	that	that	WDT
cord-353633-a4pu6rlu	94	12	affect	affect	VBP
cord-353633-a4pu6rlu	94	13	cytoskeleton	cytoskeleton	NNP
cord-353633-a4pu6rlu	94	14	organization	organization	NN
cord-353633-a4pu6rlu	94	15	,	,	,
cord-353633-a4pu6rlu	94	16	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	94	17	activity	activity	NN
cord-353633-a4pu6rlu	94	18	and	and	CC
cord-353633-a4pu6rlu	94	19	cell	cell	NN
cord-353633-a4pu6rlu	94	20	proliferation	proliferation	NN
cord-353633-a4pu6rlu	94	21	and	and	CC
cord-353633-a4pu6rlu	94	22	another	another	DT
cord-353633-a4pu6rlu	94	23	that	that	WDT
cord-353633-a4pu6rlu	94	24	was	be	VBD
cord-353633-a4pu6rlu	94	25	associated	associate	VBN
cord-353633-a4pu6rlu	94	26	with	with	IN
cord-353633-a4pu6rlu	94	27	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	94	28	pathways	pathway	NNS
cord-353633-a4pu6rlu	94	29	.	.	.
cord-353633-a4pu6rlu	95	1	The	the	DT
cord-353633-a4pu6rlu	95	2	CpG	cpg	NN
cord-353633-a4pu6rlu	95	3	methylation	methylation	NN
cord-353633-a4pu6rlu	95	4	levels	level	NNS
cord-353633-a4pu6rlu	95	5	in	in	IN
cord-353633-a4pu6rlu	95	6	both	both	DT
cord-353633-a4pu6rlu	95	7	networks	network	NNS
cord-353633-a4pu6rlu	95	8	were	be	VBD
cord-353633-a4pu6rlu	95	9	affected	affect	VBN
cord-353633-a4pu6rlu	95	10	by	by	IN
cord-353633-a4pu6rlu	95	11	age	age	NN
cord-353633-a4pu6rlu	95	12	and	and	CC
cord-353633-a4pu6rlu	95	13	fasting	fast	VBG
cord-353633-a4pu6rlu	95	14	plasma	plasma	NN
cord-353633-a4pu6rlu	95	15	glucose	glucose	NN
cord-353633-a4pu6rlu	95	16	levels	level	NNS
cord-353633-a4pu6rlu	95	17	and	and	CC
cord-353633-a4pu6rlu	95	18	for	for	IN
cord-353633-a4pu6rlu	95	19	the	the	DT
cord-353633-a4pu6rlu	95	20	second	second	JJ
cord-353633-a4pu6rlu	95	21	network	network	NN
cord-353633-a4pu6rlu	95	22	the	the	DT
cord-353633-a4pu6rlu	95	23	changes	change	NNS
cord-353633-a4pu6rlu	95	24	in	in	IN
cord-353633-a4pu6rlu	95	25	methylation	methylation	NN
cord-353633-a4pu6rlu	95	26	levels	level	NNS
cord-353633-a4pu6rlu	95	27	were	be	VBD
cord-353633-a4pu6rlu	95	28	partially	partially	RB
cord-353633-a4pu6rlu	95	29	corrected	correct	VBN
cord-353633-a4pu6rlu	95	30	by	by	IN
cord-353633-a4pu6rlu	95	31	controlling	control	VBG
cord-353633-a4pu6rlu	95	32	weight	weight	NN
cord-353633-a4pu6rlu	95	33	and	and	CC
cord-353633-a4pu6rlu	95	34	blood	blood	NN
cord-353633-a4pu6rlu	95	35	glucose	glucose	NN
cord-353633-a4pu6rlu	95	36	levels	level	NNS
cord-353633-a4pu6rlu	95	37	[	[	-LRB-
cord-353633-a4pu6rlu	95	38	68	68	CD
cord-353633-a4pu6rlu	95	39	]	]	-RRB-
cord-353633-a4pu6rlu	95	40	.	.	.
cord-353633-a4pu6rlu	96	1	J	J	NNP
cord-353633-a4pu6rlu	96	2	o	o	NN
cord-353633-a4pu6rlu	96	3	u	u	NN
cord-353633-a4pu6rlu	96	4	r	r	NN
cord-353633-a4pu6rlu	96	5	n	n	NN
cord-353633-a4pu6rlu	96	6	a	a	DT
cord-353633-a4pu6rlu	96	7	l	l	NN
cord-353633-a4pu6rlu	96	8	P	p	NN
cord-353633-a4pu6rlu	96	9	r	r	NN
cord-353633-a4pu6rlu	96	10	e	e	NN
cord-353633-a4pu6rlu	96	11	-p	-p	NN
cord-353633-a4pu6rlu	96	12	r	r	NN
cord-353633-a4pu6rlu	96	13	o	o	NN
cord-353633-a4pu6rlu	96	14	o	o	NN
cord-353633-a4pu6rlu	96	15	f	f	NN
cord-353633-a4pu6rlu	96	16	19	19	CD
cord-353633-a4pu6rlu	96	17	Histone	Histone	NNP
cord-353633-a4pu6rlu	96	18	modifications	modification	NNS
cord-353633-a4pu6rlu	96	19	are	be	VBP
cord-353633-a4pu6rlu	96	20	also	also	RB
cord-353633-a4pu6rlu	96	21	important	important	JJ
cord-353633-a4pu6rlu	96	22	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	96	23	changes	change	NNS
cord-353633-a4pu6rlu	96	24	that	that	WDT
cord-353633-a4pu6rlu	96	25	affect	affect	VBP
cord-353633-a4pu6rlu	96	26	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	96	27	activity	activity	NN
cord-353633-a4pu6rlu	96	28	and	and	CC
cord-353633-a4pu6rlu	96	29	refer	refer	VB
cord-353633-a4pu6rlu	96	30	to	to	IN
cord-353633-a4pu6rlu	96	31	several	several	JJ
cord-353633-a4pu6rlu	96	32	posttranslational	posttranslational	JJ
cord-353633-a4pu6rlu	96	33	procedures	procedure	NNS
cord-353633-a4pu6rlu	96	34	such	such	JJ
cord-353633-a4pu6rlu	96	35	as	as	IN
cord-353633-a4pu6rlu	96	36	acetylation	acetylation	NN
cord-353633-a4pu6rlu	96	37	,	,	,
cord-353633-a4pu6rlu	96	38	phosphorylation	phosphorylation	NN
cord-353633-a4pu6rlu	96	39	,	,	,
cord-353633-a4pu6rlu	96	40	methylation	methylation	NN
cord-353633-a4pu6rlu	96	41	and	and	CC
cord-353633-a4pu6rlu	96	42	ubiquitination	ubiquitination	NN
cord-353633-a4pu6rlu	96	43	.	.	.
cord-353633-a4pu6rlu	97	1	Among	among	IN
cord-353633-a4pu6rlu	97	2	them	-PRON-	PRP
cord-353633-a4pu6rlu	97	3	,	,	,
cord-353633-a4pu6rlu	97	4	acetylation	acetylation	NN
cord-353633-a4pu6rlu	97	5	status	status	NN
cord-353633-a4pu6rlu	97	6	has	have	VBZ
cord-353633-a4pu6rlu	97	7	been	be	VBN
cord-353633-a4pu6rlu	97	8	most	most	RBS
cord-353633-a4pu6rlu	97	9	vigorously	vigorously	RB
cord-353633-a4pu6rlu	97	10	studied	study	VBN
cord-353633-a4pu6rlu	97	11	and	and	CC
cord-353633-a4pu6rlu	97	12	is	be	VBZ
cord-353633-a4pu6rlu	97	13	considered	consider	VBN
cord-353633-a4pu6rlu	97	14	the	the	DT
cord-353633-a4pu6rlu	97	15	net	net	JJ
cord-353633-a4pu6rlu	97	16	result	result	NN
cord-353633-a4pu6rlu	97	17	of	of	IN
cord-353633-a4pu6rlu	97	18	histone	histone	NN
cord-353633-a4pu6rlu	97	19	acetylation	acetylation	NN
cord-353633-a4pu6rlu	97	20	by	by	IN
cord-353633-a4pu6rlu	97	21	histone	histone	NN
cord-353633-a4pu6rlu	97	22	acetyltransferases	acetyltransferase	NNS
cord-353633-a4pu6rlu	97	23	(	(	-LRB-
cord-353633-a4pu6rlu	97	24	HATs	HATs	NNP
cord-353633-a4pu6rlu	97	25	)	)	-RRB-
cord-353633-a4pu6rlu	97	26	and	and	CC
cord-353633-a4pu6rlu	97	27	histone	histone	JJ
cord-353633-a4pu6rlu	97	28	deacetylation	deacetylation	NN
cord-353633-a4pu6rlu	97	29	by	by	IN
cord-353633-a4pu6rlu	97	30	histone	histone	NN
cord-353633-a4pu6rlu	97	31	deacetylases	deacetylase	NNS
cord-353633-a4pu6rlu	97	32	(	(	-LRB-
cord-353633-a4pu6rlu	97	33	HDACs	hdac	NNS
cord-353633-a4pu6rlu	97	34	)	)	-RRB-
cord-353633-a4pu6rlu	98	1	[	[	-LRB-
cord-353633-a4pu6rlu	98	2	69	69	CD
cord-353633-a4pu6rlu	98	3	]	]	-RRB-
cord-353633-a4pu6rlu	98	4	.	.	.
cord-353633-a4pu6rlu	99	1	Acetylation	Acetylation	NNP
cord-353633-a4pu6rlu	99	2	neutralizes	neutralize	VBZ
cord-353633-a4pu6rlu	99	3	lysin	lysin	NNP
cord-353633-a4pu6rlu	99	4	's	's	POS
cord-353633-a4pu6rlu	99	5	positive	positive	JJ
cord-353633-a4pu6rlu	99	6	charge	charge	NN
cord-353633-a4pu6rlu	99	7	,	,	,
cord-353633-a4pu6rlu	99	8	thus	thus	RB
cord-353633-a4pu6rlu	99	9	leading	lead	VBG
cord-353633-a4pu6rlu	99	10	to	to	IN
cord-353633-a4pu6rlu	99	11	a	a	DT
cord-353633-a4pu6rlu	99	12	looser	loose	JJR
cord-353633-a4pu6rlu	99	13	chromatin	chromatin	NN
cord-353633-a4pu6rlu	99	14	structure	structure	NN
cord-353633-a4pu6rlu	99	15	that	that	WDT
cord-353633-a4pu6rlu	99	16	facilitates	facilitate	VBZ
cord-353633-a4pu6rlu	99	17	transcription	transcription	NN
cord-353633-a4pu6rlu	99	18	.	.	.
cord-353633-a4pu6rlu	100	1	The	the	DT
cord-353633-a4pu6rlu	100	2	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	100	3	coactivator	coactivator	NN
cord-353633-a4pu6rlu	100	4	p300	p300	NNP
cord-353633-a4pu6rlu	100	5	belongs	belong	VBZ
cord-353633-a4pu6rlu	100	6	to	to	IN
cord-353633-a4pu6rlu	100	7	HAT	hat	NN
cord-353633-a4pu6rlu	100	8	proteins	protein	NNS
cord-353633-a4pu6rlu	100	9	,	,	,
cord-353633-a4pu6rlu	100	10	whereas	whereas	IN
cord-353633-a4pu6rlu	100	11	sirtuins	sirtuin	NNS
cord-353633-a4pu6rlu	100	12	belong	belong	VBP
cord-353633-a4pu6rlu	100	13	to	to	IN
cord-353633-a4pu6rlu	100	14	NAD	NAD	NNP
cord-353633-a4pu6rlu	100	15	-	-	HYPH
cord-353633-a4pu6rlu	100	16	dependent	dependent	JJ
cord-353633-a4pu6rlu	100	17	class	class	NN
cord-353633-a4pu6rlu	100	18	III	iii	CD
cord-353633-a4pu6rlu	100	19	HDACs	hdac	NNS
cord-353633-a4pu6rlu	100	20	.	.	.
cord-353633-a4pu6rlu	101	1	Glucose	glucose	NN
cord-353633-a4pu6rlu	101	2	-	-	HYPH
cord-353633-a4pu6rlu	101	3	induced	induce	VBN
cord-353633-a4pu6rlu	101	4	activation	activation	NN
cord-353633-a4pu6rlu	101	5	of	of	IN
cord-353633-a4pu6rlu	101	6	p300	p300	NNP
cord-353633-a4pu6rlu	101	7	increases	increase	VBZ
cord-353633-a4pu6rlu	101	8	the	the	DT
cord-353633-a4pu6rlu	101	9	transcription	transcription	NN
cord-353633-a4pu6rlu	101	10	of	of	IN
cord-353633-a4pu6rlu	101	11	carbohydrate	carbohydrate	NN
cord-353633-a4pu6rlu	101	12	-	-	HYPH
cord-353633-a4pu6rlu	101	13	responsive	responsive	JJ
cord-353633-a4pu6rlu	101	14	element	element	NN
cord-353633-a4pu6rlu	101	15	-	-	HYPH
cord-353633-a4pu6rlu	101	16	binding	bind	VBG
cord-353633-a4pu6rlu	101	17	protein	protein	NN
cord-353633-a4pu6rlu	101	18	(	(	-LRB-
cord-353633-a4pu6rlu	101	19	ChREBP	ChREBP	NNP
cord-353633-a4pu6rlu	101	20	)	)	-RRB-
cord-353633-a4pu6rlu	101	21	resulting	result	VBG
cord-353633-a4pu6rlu	101	22	in	in	IN
cord-353633-a4pu6rlu	101	23	the	the	DT
cord-353633-a4pu6rlu	101	24	stimulation	stimulation	NN
cord-353633-a4pu6rlu	101	25	of	of	IN
cord-353633-a4pu6rlu	101	26	lipogenic	lipogenic	NNP
cord-353633-a4pu6rlu	101	27	genes	gene	NNS
cord-353633-a4pu6rlu	101	28	through	through	IN
cord-353633-a4pu6rlu	101	29	histone	histone	NN
cord-353633-a4pu6rlu	101	30	acetylation	acetylation	NN
cord-353633-a4pu6rlu	101	31	and	and	CC
cord-353633-a4pu6rlu	101	32	thus	thus	RB
cord-353633-a4pu6rlu	101	33	promoting	promote	VBG
cord-353633-a4pu6rlu	101	34	the	the	DT
cord-353633-a4pu6rlu	101	35	development	development	NN
cord-353633-a4pu6rlu	101	36	of	of	IN
cord-353633-a4pu6rlu	101	37	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	101	38	[	[	-LRB-
cord-353633-a4pu6rlu	101	39	69	69	CD
cord-353633-a4pu6rlu	101	40	]	]	-RRB-
cord-353633-a4pu6rlu	101	41	.	.	.
cord-353633-a4pu6rlu	102	1	Tannic	tannic	JJ
cord-353633-a4pu6rlu	102	2	acid	acid	NN
cord-353633-a4pu6rlu	102	3	attenuated	attenuate	VBD
cord-353633-a4pu6rlu	102	4	the	the	DT
cord-353633-a4pu6rlu	102	5	effects	effect	NNS
cord-353633-a4pu6rlu	102	6	of	of	IN
cord-353633-a4pu6rlu	102	7	p300	p300	NN
cord-353633-a4pu6rlu	102	8	leading	lead	VBG
cord-353633-a4pu6rlu	102	9	to	to	IN
cord-353633-a4pu6rlu	102	10	a	a	DT
cord-353633-a4pu6rlu	102	11	decrease	decrease	NN
cord-353633-a4pu6rlu	102	12	in	in	IN
cord-353633-a4pu6rlu	102	13	the	the	DT
cord-353633-a4pu6rlu	102	14	lipogenesis	lipogenesis	NN
cord-353633-a4pu6rlu	102	15	-	-	HYPH
cord-353633-a4pu6rlu	102	16	related	relate	VBN
cord-353633-a4pu6rlu	102	17	genes	gene	NNS
cord-353633-a4pu6rlu	102	18	and	and	CC
cord-353633-a4pu6rlu	102	19	to	to	IN
cord-353633-a4pu6rlu	102	20	an	an	DT
cord-353633-a4pu6rlu	102	21	improvement	improvement	NN
cord-353633-a4pu6rlu	102	22	of	of	IN
cord-353633-a4pu6rlu	102	23	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	102	24	in	in	IN
cord-353633-a4pu6rlu	102	25	mice	mouse	NNS
cord-353633-a4pu6rlu	102	26	[	[	-LRB-
cord-353633-a4pu6rlu	102	27	70	70	CD
cord-353633-a4pu6rlu	102	28	]	]	-RRB-
cord-353633-a4pu6rlu	102	29	.	.	.
cord-353633-a4pu6rlu	103	1	Similarly	similarly	RB
cord-353633-a4pu6rlu	103	2	,	,	,
cord-353633-a4pu6rlu	103	3	inhibition	inhibition	NN
cord-353633-a4pu6rlu	103	4	of	of	IN
cord-353633-a4pu6rlu	103	5	cdk4	cdk4	NNP
cord-353633-a4pu6rlu	103	6	protein	protein	NN
cord-353633-a4pu6rlu	103	7	reduces	reduce	VBZ
cord-353633-a4pu6rlu	103	8	the	the	DT
cord-353633-a4pu6rlu	103	9	formation	formation	NN
cord-353633-a4pu6rlu	103	10	of	of	IN
cord-353633-a4pu6rlu	103	11	C	C	NNP
cord-353633-a4pu6rlu	103	12	/	/	SYM
cord-353633-a4pu6rlu	103	13	EBPα	EBPα	NNS
cord-353633-a4pu6rlu	103	14	-p300	-p300	NNP
cord-353633-a4pu6rlu	103	15	complexes	complex	NNS
cord-353633-a4pu6rlu	103	16	reducing	reduce	VBG
cord-353633-a4pu6rlu	103	17	liver	liver	NN
cord-353633-a4pu6rlu	103	18	steatosis	steatosis	NN
cord-353633-a4pu6rlu	103	19	and	and	CC
cord-353633-a4pu6rlu	103	20	correcting	correct	VBG
cord-353633-a4pu6rlu	103	21	age	age	NN
cord-353633-a4pu6rlu	103	22	-	-	HYPH
cord-353633-a4pu6rlu	103	23	associated	associate	VBN
cord-353633-a4pu6rlu	103	24	liver	liver	NN
cord-353633-a4pu6rlu	103	25	changes	change	NNS
cord-353633-a4pu6rlu	103	26	[	[	-LRB-
cord-353633-a4pu6rlu	103	27	71	71	CD
cord-353633-a4pu6rlu	103	28	]	]	-RRB-
cord-353633-a4pu6rlu	103	29	.	.	.
cord-353633-a4pu6rlu	104	1	P300	P300	NNP
cord-353633-a4pu6rlu	104	2	may	may	MD
cord-353633-a4pu6rlu	104	3	also	also	RB
cord-353633-a4pu6rlu	104	4	be	be	VB
cord-353633-a4pu6rlu	104	5	involved	involve	VBN
cord-353633-a4pu6rlu	104	6	in	in	IN
cord-353633-a4pu6rlu	104	7	the	the	DT
cord-353633-a4pu6rlu	104	8	activation	activation	NN
cord-353633-a4pu6rlu	104	9	of	of	IN
cord-353633-a4pu6rlu	104	10	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	104	11	stellate	stellate	JJ
cord-353633-a4pu6rlu	104	12	cells	cell	NNS
cord-353633-a4pu6rlu	104	13	and	and	CC
cord-353633-a4pu6rlu	104	14	their	-PRON-	PRP$
cord-353633-a4pu6rlu	104	15	transdifferentiation	transdifferentiation	NN
cord-353633-a4pu6rlu	104	16	to	to	IN
cord-353633-a4pu6rlu	104	17	myofibroblasts	myofibroblast	NNS
cord-353633-a4pu6rlu	104	18	[	[	-LRB-
cord-353633-a4pu6rlu	104	19	72	72	CD
cord-353633-a4pu6rlu	104	20	]	]	-RRB-
cord-353633-a4pu6rlu	104	21	.	.	.
cord-353633-a4pu6rlu	105	1	Among	among	IN
cord-353633-a4pu6rlu	105	2	the	the	DT
cord-353633-a4pu6rlu	105	3	Sirtuins	Sirtuins	NNPS
cord-353633-a4pu6rlu	105	4	,	,	,
cord-353633-a4pu6rlu	105	5	especially	especially	RB
cord-353633-a4pu6rlu	105	6	Sirtuin	Sirtuin	NNP
cord-353633-a4pu6rlu	105	7	1	1	CD
cord-353633-a4pu6rlu	105	8	(	(	-LRB-
cord-353633-a4pu6rlu	105	9	SIRT1	SIRT1	NNP
cord-353633-a4pu6rlu	105	10	)	)	-RRB-
cord-353633-a4pu6rlu	105	11	has	have	VBZ
cord-353633-a4pu6rlu	105	12	been	be	VBN
cord-353633-a4pu6rlu	105	13	shown	show	VBN
cord-353633-a4pu6rlu	105	14	to	to	TO
cord-353633-a4pu6rlu	105	15	participate	participate	VB
cord-353633-a4pu6rlu	105	16	in	in	IN
cord-353633-a4pu6rlu	105	17	the	the	DT
cord-353633-a4pu6rlu	105	18	regulation	regulation	NN
cord-353633-a4pu6rlu	105	19	of	of	IN
cord-353633-a4pu6rlu	105	20	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	105	21	metabolism	metabolism	NN
cord-353633-a4pu6rlu	105	22	and	and	CC
cord-353633-a4pu6rlu	105	23	insulin	insulin	NN
cord-353633-a4pu6rlu	105	24	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	105	25	,	,	,
cord-353633-a4pu6rlu	105	26	with	with	IN
cord-353633-a4pu6rlu	105	27	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	105	28	deletion	deletion	NN
cord-353633-a4pu6rlu	105	29	of	of	IN
cord-353633-a4pu6rlu	105	30	SIRT1	sirt1	NN
cord-353633-a4pu6rlu	105	31	resulting	result	VBG
cord-353633-a4pu6rlu	105	32	in	in	IN
cord-353633-a4pu6rlu	105	33	steatosis	steatosis	NN
cord-353633-a4pu6rlu	105	34	and	and	CC
cord-353633-a4pu6rlu	105	35	inflammation	inflammation	NN
cord-353633-a4pu6rlu	105	36	,	,	,
cord-353633-a4pu6rlu	105	37	whereas	whereas	IN
cord-353633-a4pu6rlu	105	38	overexpression	overexpression	NN
cord-353633-a4pu6rlu	105	39	of	of	IN
cord-353633-a4pu6rlu	105	40	SIRT1	sirt1	NN
cord-353633-a4pu6rlu	105	41	protecting	protect	VBG
cord-353633-a4pu6rlu	105	42	from	from	IN
cord-353633-a4pu6rlu	105	43	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	105	44	[	[	-LRB-
cord-353633-a4pu6rlu	105	45	73	73	CD
cord-353633-a4pu6rlu	105	46	]	]	-RRB-
cord-353633-a4pu6rlu	105	47	[	[	-LRB-
cord-353633-a4pu6rlu	105	48	74	74	CD
cord-353633-a4pu6rlu	105	49	]	]	-RRB-
cord-353633-a4pu6rlu	105	50	[	[	-LRB-
cord-353633-a4pu6rlu	105	51	75	75	CD
cord-353633-a4pu6rlu	105	52	]	]	-RRB-
cord-353633-a4pu6rlu	105	53	.	.	.
cord-353633-a4pu6rlu	106	1	Similarly	similarly	RB
cord-353633-a4pu6rlu	106	2	,	,	,
cord-353633-a4pu6rlu	106	3	SIRT3	sirt3	JJ
cord-353633-a4pu6rlu	106	4	deficiency	deficiency	NN
cord-353633-a4pu6rlu	106	5	leads	lead	VBZ
cord-353633-a4pu6rlu	106	6	to	to	IN
cord-353633-a4pu6rlu	106	7	insulin	insulin	NN
cord-353633-a4pu6rlu	106	8	resistance	resistance	NN
cord-353633-a4pu6rlu	106	9	,	,	,
cord-353633-a4pu6rlu	106	10	hyperlipidemia	hyperlipidemia	NN
cord-353633-a4pu6rlu	106	11	and	and	CC
cord-353633-a4pu6rlu	106	12	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	106	13	in	in	IN
cord-353633-a4pu6rlu	106	14	mice	mouse	NNS
cord-353633-a4pu6rlu	106	15	[	[	-LRB-
cord-353633-a4pu6rlu	106	16	76	76	CD
cord-353633-a4pu6rlu	106	17	]	]	-RRB-
cord-353633-a4pu6rlu	106	18	whereas	whereas	IN
cord-353633-a4pu6rlu	106	19	a	a	DT
cord-353633-a4pu6rlu	106	20	polymorphism	polymorphism	NN
cord-353633-a4pu6rlu	106	21	of	of	IN
cord-353633-a4pu6rlu	106	22	SIRT3	sirt3	NN
cord-353633-a4pu6rlu	106	23	is	be	VBZ
cord-353633-a4pu6rlu	106	24	associated	associate	VBN
cord-353633-a4pu6rlu	106	25	with	with	IN
cord-353633-a4pu6rlu	106	26	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	106	27	syndrome	syndrome	NN
cord-353633-a4pu6rlu	106	28	and	and	CC
cord-353633-a4pu6rlu	106	29	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	106	30	in	in	IN
cord-353633-a4pu6rlu	106	31	humans	human	NNS
cord-353633-a4pu6rlu	106	32	[	[	-LRB-
cord-353633-a4pu6rlu	106	33	77	77	CD
cord-353633-a4pu6rlu	106	34	]	]	-RRB-
cord-353633-a4pu6rlu	106	35	.	.	.
cord-353633-a4pu6rlu	107	1	HDAC3	HDAC3	NNP
cord-353633-a4pu6rlu	107	2	,	,	,
cord-353633-a4pu6rlu	107	3	a	a	DT
cord-353633-a4pu6rlu	107	4	member	member	NN
cord-353633-a4pu6rlu	107	5	of	of	IN
cord-353633-a4pu6rlu	107	6	J	J	NNP
cord-353633-a4pu6rlu	107	7	o	o	NNP
cord-353633-a4pu6rlu	108	1	u	u	NNP
cord-353633-a4pu6rlu	108	2	r	r	NNP
cord-353633-a4pu6rlu	108	3	n	n	NN
cord-353633-a4pu6rlu	109	1	a	a	DT
cord-353633-a4pu6rlu	109	2	l	l	NN
cord-353633-a4pu6rlu	109	3	P	p	NN
cord-353633-a4pu6rlu	109	4	r	r	NN
cord-353633-a4pu6rlu	109	5	e	e	NN
cord-353633-a4pu6rlu	109	6	-p	-p	NN
cord-353633-a4pu6rlu	109	7	r	r	NN
cord-353633-a4pu6rlu	109	8	o	o	NN
cord-353633-a4pu6rlu	109	9	o	o	NN
cord-353633-a4pu6rlu	109	10	f	f	NN
cord-353633-a4pu6rlu	109	11	20	20	CD
cord-353633-a4pu6rlu	109	12	human	human	JJ
cord-353633-a4pu6rlu	109	13	class	class	NN
cord-353633-a4pu6rlu	110	1	I	-PRON-	PRP
cord-353633-a4pu6rlu	110	2	HDACs	hdac	NNS
cord-353633-a4pu6rlu	110	3	has	have	VBZ
cord-353633-a4pu6rlu	110	4	been	be	VBN
cord-353633-a4pu6rlu	110	5	also	also	RB
cord-353633-a4pu6rlu	110	6	implicated	implicate	VBN
cord-353633-a4pu6rlu	110	7	with	with	IN
cord-353633-a4pu6rlu	110	8	circadian	circadian	JJ
cord-353633-a4pu6rlu	110	9	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	110	10	rhythm	rhythm	NN
cord-353633-a4pu6rlu	110	11	and	and	CC
cord-353633-a4pu6rlu	110	12	its	-PRON-	PRP$
cord-353633-a4pu6rlu	110	13	deletion	deletion	NN
cord-353633-a4pu6rlu	110	14	leads	lead	VBZ
cord-353633-a4pu6rlu	110	15	to	to	IN
cord-353633-a4pu6rlu	110	16	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	110	17	steatosis	steatosis	NN
cord-353633-a4pu6rlu	110	18	in	in	IN
cord-353633-a4pu6rlu	110	19	mouse	mouse	NN
cord-353633-a4pu6rlu	110	20	liver	liver	NN
cord-353633-a4pu6rlu	110	21	[	[	-LRB-
cord-353633-a4pu6rlu	110	22	78	78	CD
cord-353633-a4pu6rlu	110	23	]	]	-RRB-
cord-353633-a4pu6rlu	110	24	.	.	.
cord-353633-a4pu6rlu	111	1	Altogether	altogether	RB
cord-353633-a4pu6rlu	111	2	,	,	,
cord-353633-a4pu6rlu	111	3	there	there	EX
cord-353633-a4pu6rlu	111	4	is	be	VBZ
cord-353633-a4pu6rlu	111	5	increasing	increase	VBG
cord-353633-a4pu6rlu	111	6	evidence	evidence	NN
cord-353633-a4pu6rlu	111	7	that	that	IN
cord-353633-a4pu6rlu	111	8	both	both	CC
cord-353633-a4pu6rlu	111	9	DNA	dna	NN
cord-353633-a4pu6rlu	111	10	methylation	methylation	NN
cord-353633-a4pu6rlu	111	11	as	as	RB
cord-353633-a4pu6rlu	111	12	well	well	RB
cord-353633-a4pu6rlu	111	13	as	as	IN
cord-353633-a4pu6rlu	111	14	histone	histone	NN
cord-353633-a4pu6rlu	111	15	modifications	modification	NNS
cord-353633-a4pu6rlu	111	16	play	play	VBP
cord-353633-a4pu6rlu	111	17	a	a	DT
cord-353633-a4pu6rlu	111	18	crucial	crucial	JJ
cord-353633-a4pu6rlu	111	19	role	role	NN
cord-353633-a4pu6rlu	111	20	in	in	IN
cord-353633-a4pu6rlu	111	21	the	the	DT
cord-353633-a4pu6rlu	111	22	development	development	NN
cord-353633-a4pu6rlu	111	23	and	and	CC
cord-353633-a4pu6rlu	111	24	progress	progress	NN
cord-353633-a4pu6rlu	111	25	of	of	IN
cord-353633-a4pu6rlu	111	26	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	111	27	.	.	.
cord-353633-a4pu6rlu	112	1	An	an	DT
cord-353633-a4pu6rlu	112	2	important	important	JJ
cord-353633-a4pu6rlu	112	3	question	question	NN
cord-353633-a4pu6rlu	112	4	is	be	VBZ
cord-353633-a4pu6rlu	112	5	whether	whether	IN
cord-353633-a4pu6rlu	112	6	the	the	DT
cord-353633-a4pu6rlu	112	7	numerous	numerous	JJ
cord-353633-a4pu6rlu	112	8	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	112	9	changes	change	NNS
cord-353633-a4pu6rlu	112	10	observed	observe	VBN
cord-353633-a4pu6rlu	112	11	in	in	IN
cord-353633-a4pu6rlu	112	12	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	112	13	in	in	IN
cord-353633-a4pu6rlu	112	14	combination	combination	NN
cord-353633-a4pu6rlu	112	15	with	with	IN
cord-353633-a4pu6rlu	112	16	the	the	DT
cord-353633-a4pu6rlu	112	17	highly	highly	RB
cord-353633-a4pu6rlu	112	18	dynamic	dynamic	JJ
cord-353633-a4pu6rlu	112	19	nature	nature	NN
cord-353633-a4pu6rlu	112	20	of	of	IN
cord-353633-a4pu6rlu	112	21	epigenome	epigenome	NN
cord-353633-a4pu6rlu	112	22	can	can	MD
cord-353633-a4pu6rlu	112	23	serve	serve	VB
cord-353633-a4pu6rlu	112	24	as	as	RB
cord-353633-a4pu6rlu	112	25	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	112	26	or	or	CC
cord-353633-a4pu6rlu	112	27	prognostic	prognostic	JJ
cord-353633-a4pu6rlu	112	28	markers	marker	NNS
cord-353633-a4pu6rlu	112	29	of	of	IN
cord-353633-a4pu6rlu	112	30	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	112	31	or	or	CC
cord-353633-a4pu6rlu	112	32	even	even	RB
cord-353633-a4pu6rlu	112	33	as	as	IN
cord-353633-a4pu6rlu	112	34	markers	marker	NNS
cord-353633-a4pu6rlu	112	35	of	of	IN
cord-353633-a4pu6rlu	112	36	treatment	treatment	NN
cord-353633-a4pu6rlu	112	37	response	response	NN
cord-353633-a4pu6rlu	112	38	.	.	.
cord-353633-a4pu6rlu	113	1	Very	very	RB
cord-353633-a4pu6rlu	113	2	few	few	JJ
cord-353633-a4pu6rlu	113	3	studies	study	NNS
cord-353633-a4pu6rlu	113	4	have	have	VBP
cord-353633-a4pu6rlu	113	5	addressed	address	VBN
cord-353633-a4pu6rlu	113	6	this	this	DT
cord-353633-a4pu6rlu	113	7	point	point	NN
cord-353633-a4pu6rlu	113	8	so	so	RB
cord-353633-a4pu6rlu	113	9	far	far	RB
cord-353633-a4pu6rlu	113	10	.	.	.
cord-353633-a4pu6rlu	114	1	One	one	CD
cord-353633-a4pu6rlu	114	2	of	of	IN
cord-353633-a4pu6rlu	114	3	them	-PRON-	PRP
cord-353633-a4pu6rlu	114	4	that	that	WDT
cord-353633-a4pu6rlu	114	5	included	include	VBD
cord-353633-a4pu6rlu	114	6	a	a	DT
cord-353633-a4pu6rlu	114	7	small	small	JJ
cord-353633-a4pu6rlu	114	8	number	number	NN
cord-353633-a4pu6rlu	114	9	of	of	IN
cord-353633-a4pu6rlu	114	10	patients	patient	NNS
cord-353633-a4pu6rlu	114	11	with	with	IN
cord-353633-a4pu6rlu	114	12	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	114	13	has	have	VBZ
cord-353633-a4pu6rlu	114	14	shown	show	VBN
cord-353633-a4pu6rlu	114	15	that	that	IN
cord-353633-a4pu6rlu	114	16	alterations	alteration	NNS
cord-353633-a4pu6rlu	114	17	in	in	IN
cord-353633-a4pu6rlu	114	18	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	114	19	DNA	dna	NN
cord-353633-a4pu6rlu	114	20	methylation	methylation	NN
cord-353633-a4pu6rlu	114	21	may	may	MD
cord-353633-a4pu6rlu	114	22	be	be	VB
cord-353633-a4pu6rlu	114	23	sufficiently	sufficiently	RB
cord-353633-a4pu6rlu	114	24	reflected	reflect	VBN
cord-353633-a4pu6rlu	114	25	in	in	IN
cord-353633-a4pu6rlu	114	26	plasma	plasma	NN
cord-353633-a4pu6rlu	114	27	.	.	.
cord-353633-a4pu6rlu	115	1	In	in	IN
cord-353633-a4pu6rlu	115	2	this	this	DT
cord-353633-a4pu6rlu	115	3	study	study	NN
cord-353633-a4pu6rlu	115	4	,	,	,
cord-353633-a4pu6rlu	115	5	%	%	NN
cord-353633-a4pu6rlu	115	6	of	of	IN
cord-353633-a4pu6rlu	115	7	plasma	plasma	NN
cord-353633-a4pu6rlu	115	8	DNA	dna	NN
cord-353633-a4pu6rlu	115	9	methylation	methylation	NN
cord-353633-a4pu6rlu	115	10	of	of	IN
cord-353633-a4pu6rlu	115	11	PPARγ	PPARγ	NNS
cord-353633-a4pu6rlu	115	12	was	be	VBD
cord-353633-a4pu6rlu	115	13	used	use	VBN
cord-353633-a4pu6rlu	115	14	to	to	TO
cord-353633-a4pu6rlu	115	15	identify	identify	VB
cord-353633-a4pu6rlu	115	16	subjects	subject	NNS
cord-353633-a4pu6rlu	115	17	with	with	IN
cord-353633-a4pu6rlu	115	18	severe	severe	JJ
cord-353633-a4pu6rlu	115	19	(	(	-LRB-
cord-353633-a4pu6rlu	115	20	Kleiner	Kleiner	NNP
cord-353633-a4pu6rlu	115	21	3	3	CD
cord-353633-a4pu6rlu	115	22	-	-	SYM
cord-353633-a4pu6rlu	115	23	4	4	CD
cord-353633-a4pu6rlu	115	24	)	)	-RRB-
cord-353633-a4pu6rlu	115	25	vs	vs	IN
cord-353633-a4pu6rlu	115	26	mild	mild	JJ
cord-353633-a4pu6rlu	115	27	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	115	28	(	(	-LRB-
cord-353633-a4pu6rlu	115	29	Kleiner	Kleiner	NNP
cord-353633-a4pu6rlu	115	30	1	1	CD
cord-353633-a4pu6rlu	115	31	-	-	SYM
cord-353633-a4pu6rlu	115	32	2	2	CD
cord-353633-a4pu6rlu	115	33	)	)	-RRB-
cord-353633-a4pu6rlu	115	34	.	.	.
cord-353633-a4pu6rlu	116	1	The	the	DT
cord-353633-a4pu6rlu	116	2	threshold	threshold	NN
cord-353633-a4pu6rlu	116	3	of	of	IN
cord-353633-a4pu6rlu	116	4	methylation	methylation	NN
cord-353633-a4pu6rlu	116	5	was	be	VBD
cord-353633-a4pu6rlu	116	6	81	81	CD
cord-353633-a4pu6rlu	116	7	%	%	NN
cord-353633-a4pu6rlu	116	8	and	and	CC
cord-353633-a4pu6rlu	116	9	demonstrated	demonstrate	VBD
cord-353633-a4pu6rlu	116	10	83	83	CD
cord-353633-a4pu6rlu	116	11	%	%	NN
cord-353633-a4pu6rlu	116	12	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	116	13	and	and	CC
cord-353633-a4pu6rlu	116	14	93	93	CD
cord-353633-a4pu6rlu	116	15	%	%	NN
cord-353633-a4pu6rlu	116	16	specificity	specificity	NN
cord-353633-a4pu6rlu	116	17	to	to	TO
cord-353633-a4pu6rlu	116	18	differentiate	differentiate	VB
cord-353633-a4pu6rlu	116	19	between	between	IN
cord-353633-a4pu6rlu	116	20	the	the	DT
cord-353633-a4pu6rlu	116	21	two	two	CD
cord-353633-a4pu6rlu	116	22	above	above	IN
cord-353633-a4pu6rlu	116	23	categories	category	NNS
cord-353633-a4pu6rlu	116	24	[	[	-LRB-
cord-353633-a4pu6rlu	116	25	79	79	CD
cord-353633-a4pu6rlu	116	26	]	]	-RRB-
cord-353633-a4pu6rlu	116	27	.	.	.
cord-353633-a4pu6rlu	117	1	Although	although	IN
cord-353633-a4pu6rlu	117	2	validation	validation	NN
cord-353633-a4pu6rlu	117	3	of	of	IN
cord-353633-a4pu6rlu	117	4	the	the	DT
cord-353633-a4pu6rlu	117	5	findings	finding	NNS
cord-353633-a4pu6rlu	117	6	in	in	IN
cord-353633-a4pu6rlu	117	7	largest	large	JJS
cord-353633-a4pu6rlu	117	8	and	and	CC
cord-353633-a4pu6rlu	117	9	more	more	RBR
cord-353633-a4pu6rlu	117	10	heterogenous	heterogenous	JJ
cord-353633-a4pu6rlu	117	11	cohorts	cohort	NNS
cord-353633-a4pu6rlu	117	12	is	be	VBZ
cord-353633-a4pu6rlu	117	13	needed	need	VBN
cord-353633-a4pu6rlu	117	14	,	,	,
cord-353633-a4pu6rlu	117	15	it	-PRON-	PRP
cord-353633-a4pu6rlu	117	16	is	be	VBZ
cord-353633-a4pu6rlu	117	17	one	one	CD
cord-353633-a4pu6rlu	117	18	of	of	IN
cord-353633-a4pu6rlu	117	19	the	the	DT
cord-353633-a4pu6rlu	117	20	first	first	JJ
cord-353633-a4pu6rlu	117	21	studies	study	NNS
cord-353633-a4pu6rlu	117	22	to	to	TO
cord-353633-a4pu6rlu	117	23	suggest	suggest	VB
cord-353633-a4pu6rlu	117	24	that	that	IN
cord-353633-a4pu6rlu	117	25	changes	change	NNS
cord-353633-a4pu6rlu	117	26	in	in	IN
cord-353633-a4pu6rlu	117	27	DNA	dna	NN
cord-353633-a4pu6rlu	117	28	methylation	methylation	NN
cord-353633-a4pu6rlu	117	29	can	can	MD
cord-353633-a4pu6rlu	117	30	have	have	VB
cord-353633-a4pu6rlu	117	31	beyond	beyond	IN
cord-353633-a4pu6rlu	117	32	their	-PRON-	PRP$
cord-353633-a4pu6rlu	117	33	pathophysiological	pathophysiological	JJ
cord-353633-a4pu6rlu	117	34	significance	significance	NN
cord-353633-a4pu6rlu	117	35	also	also	RB
cord-353633-a4pu6rlu	117	36	value	value	VBP
cord-353633-a4pu6rlu	117	37	as	as	IN
cord-353633-a4pu6rlu	117	38	potential	potential	JJ
cord-353633-a4pu6rlu	117	39	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	117	40	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	117	41	for	for	IN
cord-353633-a4pu6rlu	117	42	the	the	DT
cord-353633-a4pu6rlu	117	43	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	117	44	and	and	CC
cord-353633-a4pu6rlu	117	45	staging	staging	NN
cord-353633-a4pu6rlu	117	46	of	of	IN
cord-353633-a4pu6rlu	117	47	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	117	48	.	.	.
cord-353633-a4pu6rlu	118	1	A	a	DT
cord-353633-a4pu6rlu	118	2	second	second	JJ
cord-353633-a4pu6rlu	118	3	study	study	NN
cord-353633-a4pu6rlu	118	4	has	have	VBZ
cord-353633-a4pu6rlu	118	5	also	also	RB
cord-353633-a4pu6rlu	118	6	investigated	investigate	VBN
cord-353633-a4pu6rlu	118	7	differences	difference	NNS
cord-353633-a4pu6rlu	118	8	in	in	IN
cord-353633-a4pu6rlu	118	9	methylation	methylation	NN
cord-353633-a4pu6rlu	118	10	of	of	IN
cord-353633-a4pu6rlu	118	11	DNA	dna	NN
cord-353633-a4pu6rlu	118	12	from	from	IN
cord-353633-a4pu6rlu	118	13	peripheral	peripheral	JJ
cord-353633-a4pu6rlu	118	14	blood	blood	NN
cord-353633-a4pu6rlu	118	15	leukocytes	leukocyte	NNS
cord-353633-a4pu6rlu	118	16	that	that	WDT
cord-353633-a4pu6rlu	118	17	may	may	MD
cord-353633-a4pu6rlu	118	18	be	be	VB
cord-353633-a4pu6rlu	118	19	able	able	JJ
cord-353633-a4pu6rlu	118	20	to	to	TO
cord-353633-a4pu6rlu	118	21	discriminate	discriminate	VB
cord-353633-a4pu6rlu	118	22	between	between	IN
cord-353633-a4pu6rlu	118	23	NASH	NASH	NNP
cord-353633-a4pu6rlu	118	24	vs	vs	IN
cord-353633-a4pu6rlu	118	25	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	118	26	.	.	.
cord-353633-a4pu6rlu	119	1	The	the	DT
cord-353633-a4pu6rlu	119	2	study	study	NN
cord-353633-a4pu6rlu	119	3	identified	identify	VBD
cord-353633-a4pu6rlu	119	4	six	six	CD
cord-353633-a4pu6rlu	119	5	genes	gene	NNS
cord-353633-a4pu6rlu	119	6	that	that	WDT
cord-353633-a4pu6rlu	119	7	their	-PRON-	PRP$
cord-353633-a4pu6rlu	119	8	methylation	methylation	NN
cord-353633-a4pu6rlu	119	9	correlates	correlate	VBZ
cord-353633-a4pu6rlu	119	10	with	with	IN
cord-353633-a4pu6rlu	119	11	lobular	lobular	JJ
cord-353633-a4pu6rlu	119	12	inflammation	inflammation	NN
cord-353633-a4pu6rlu	119	13	and	and	CC
cord-353633-a4pu6rlu	119	14	can	can	MD
cord-353633-a4pu6rlu	119	15	be	be	VB
cord-353633-a4pu6rlu	119	16	potentially	potentially	RB
cord-353633-a4pu6rlu	119	17	used	use	VBN
cord-353633-a4pu6rlu	119	18	as	as	IN
cord-353633-a4pu6rlu	119	19	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	119	20	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	119	21	(	(	-LRB-
cord-353633-a4pu6rlu	119	22	with	with	IN
cord-353633-a4pu6rlu	119	23	the	the	DT
cord-353633-a4pu6rlu	119	24	J	J	NNP
cord-353633-a4pu6rlu	119	25	o	o	NN
cord-353633-a4pu6rlu	119	26	u	u	NN
cord-353633-a4pu6rlu	119	27	r	r	NN
cord-353633-a4pu6rlu	119	28	n	n	NN
cord-353633-a4pu6rlu	119	29	a	a	DT
cord-353633-a4pu6rlu	119	30	l	l	NN
cord-353633-a4pu6rlu	119	31	P	p	NN
cord-353633-a4pu6rlu	119	32	r	r	NN
cord-353633-a4pu6rlu	119	33	e	e	NN
cord-353633-a4pu6rlu	119	34	-p	-p	NN
cord-353633-a4pu6rlu	119	35	r	r	NN
cord-353633-a4pu6rlu	119	36	o	o	NN
cord-353633-a4pu6rlu	119	37	o	o	NN
cord-353633-a4pu6rlu	119	38	f	f	NN
cord-353633-a4pu6rlu	119	39	21	21	CD
cord-353633-a4pu6rlu	119	40	best	good	JJS
cord-353633-a4pu6rlu	119	41	one	one	CD
cord-353633-a4pu6rlu	119	42	showing	show	VBG
cord-353633-a4pu6rlu	119	43	99	99	CD
cord-353633-a4pu6rlu	119	44	%	%	NN
cord-353633-a4pu6rlu	119	45	specificity	specificity	NN
cord-353633-a4pu6rlu	119	46	and	and	CC
cord-353633-a4pu6rlu	119	47	71	71	CD
cord-353633-a4pu6rlu	119	48	%	%	NN
cord-353633-a4pu6rlu	119	49	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	119	50	)	)	-RRB-
cord-353633-a4pu6rlu	119	51	for	for	IN
cord-353633-a4pu6rlu	119	52	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	119	53	NASH	NASH	NNP
cord-353633-a4pu6rlu	119	54	from	from	IN
cord-353633-a4pu6rlu	119	55	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	119	56	[	[	-LRB-
cord-353633-a4pu6rlu	119	57	80	80	CD
cord-353633-a4pu6rlu	119	58	]	]	-RRB-
cord-353633-a4pu6rlu	119	59	.	.	.
cord-353633-a4pu6rlu	120	1	Finally	finally	RB
cord-353633-a4pu6rlu	120	2	,	,	,
cord-353633-a4pu6rlu	120	3	in	in	IN
cord-353633-a4pu6rlu	120	4	a	a	DT
cord-353633-a4pu6rlu	120	5	large	large	JJ
cord-353633-a4pu6rlu	120	6	epigenome	epigenome	NN
cord-353633-a4pu6rlu	120	7	-	-	HYPH
cord-353633-a4pu6rlu	120	8	wide	wide	JJ
cord-353633-a4pu6rlu	120	9	association	association	NN
cord-353633-a4pu6rlu	120	10	study	study	NN
cord-353633-a4pu6rlu	120	11	consisting	consist	VBG
cord-353633-a4pu6rlu	120	12	of	of	IN
cord-353633-a4pu6rlu	120	13	3,400	3,400	CD
cord-353633-a4pu6rlu	120	14	participants	participant	NNS
cord-353633-a4pu6rlu	120	15	of	of	IN
cord-353633-a4pu6rlu	120	16	European	european	JJ
cord-353633-a4pu6rlu	120	17	ancenstry	ancenstry	NNP
cord-353633-a4pu6rlu	120	18	,	,	,
cord-353633-a4pu6rlu	120	19	22	22	CD
cord-353633-a4pu6rlu	120	20	CpGs	CpGs	NNP
cord-353633-a4pu6rlu	120	21	were	be	VBD
cord-353633-a4pu6rlu	120	22	found	find	VBN
cord-353633-a4pu6rlu	120	23	in	in	IN
cord-353633-a4pu6rlu	120	24	peripheral	peripheral	JJ
cord-353633-a4pu6rlu	120	25	blood	blood	NN
cord-353633-a4pu6rlu	120	26	to	to	TO
cord-353633-a4pu6rlu	120	27	be	be	VB
cord-353633-a4pu6rlu	120	28	associated	associate	VBN
cord-353633-a4pu6rlu	120	29	with	with	IN
cord-353633-a4pu6rlu	120	30	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	120	31	fat	fat	NN
cord-353633-a4pu6rlu	120	32	as	as	IN
cord-353633-a4pu6rlu	120	33	assessed	assess	VBN
cord-353633-a4pu6rlu	120	34	by	by	IN
cord-353633-a4pu6rlu	120	35	computed	compute	VBN
cord-353633-a4pu6rlu	120	36	tomography	tomography	NN
cord-353633-a4pu6rlu	120	37	or	or	CC
cord-353633-a4pu6rlu	120	38	ultrasound	ultrasound	NN
cord-353633-a4pu6rlu	120	39	imaging	imaging	NN
cord-353633-a4pu6rlu	120	40	and	and	CC
cord-353633-a4pu6rlu	120	41	among	among	IN
cord-353633-a4pu6rlu	120	42	them	-PRON-	PRP
cord-353633-a4pu6rlu	120	43	one	one	CD
cord-353633-a4pu6rlu	120	44	was	be	VBD
cord-353633-a4pu6rlu	120	45	also	also	RB
cord-353633-a4pu6rlu	120	46	associated	associate	VBN
cord-353633-a4pu6rlu	120	47	with	with	IN
cord-353633-a4pu6rlu	120	48	risk	risk	NN
cord-353633-a4pu6rlu	120	49	for	for	IN
cord-353633-a4pu6rlu	120	50	new	new	JJ
cord-353633-a4pu6rlu	120	51	-	-	HYPH
cord-353633-a4pu6rlu	120	52	onset	onset	NN
cord-353633-a4pu6rlu	120	53	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	120	54	[	[	-LRB-
cord-353633-a4pu6rlu	120	55	81	81	CD
cord-353633-a4pu6rlu	120	56	]	]	-RRB-
cord-353633-a4pu6rlu	120	57	.	.	.
cord-353633-a4pu6rlu	121	1	Nevertheless	nevertheless	RB
cord-353633-a4pu6rlu	121	2	,	,	,
cord-353633-a4pu6rlu	121	3	significantly	significantly	RB
cord-353633-a4pu6rlu	121	4	more	more	JJR
cord-353633-a4pu6rlu	121	5	and	and	CC
cord-353633-a4pu6rlu	121	6	larger	large	JJR
cord-353633-a4pu6rlu	121	7	studies	study	NNS
cord-353633-a4pu6rlu	121	8	are	be	VBP
cord-353633-a4pu6rlu	121	9	needed	need	VBN
cord-353633-a4pu6rlu	121	10	in	in	IN
cord-353633-a4pu6rlu	121	11	order	order	NN
cord-353633-a4pu6rlu	121	12	to	to	TO
cord-353633-a4pu6rlu	121	13	decide	decide	VB
cord-353633-a4pu6rlu	121	14	whether	whether	IN
cord-353633-a4pu6rlu	121	15	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	121	16	changes	change	NNS
cord-353633-a4pu6rlu	121	17	in	in	IN
cord-353633-a4pu6rlu	121	18	the	the	DT
cord-353633-a4pu6rlu	121	19	blood	blood	NN
cord-353633-a4pu6rlu	121	20	can	can	MD
cord-353633-a4pu6rlu	121	21	have	have	VB
cord-353633-a4pu6rlu	121	22	any	any	DT
cord-353633-a4pu6rlu	121	23	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	121	24	or	or	CC
cord-353633-a4pu6rlu	121	25	prognostic	prognostic	JJ
cord-353633-a4pu6rlu	121	26	value	value	NN
cord-353633-a4pu6rlu	121	27	.	.	.
cord-353633-a4pu6rlu	122	1	Targeting	target	VBG
cord-353633-a4pu6rlu	122	2	epigenomic	epigenomic	JJ
cord-353633-a4pu6rlu	122	3	changes	change	NNS
cord-353633-a4pu6rlu	122	4	for	for	IN
cord-353633-a4pu6rlu	122	5	the	the	DT
cord-353633-a4pu6rlu	122	6	treatment	treatment	NN
cord-353633-a4pu6rlu	122	7	of	of	IN
cord-353633-a4pu6rlu	122	8	diseases	disease	NNS
cord-353633-a4pu6rlu	122	9	seems	seem	VBZ
cord-353633-a4pu6rlu	122	10	to	to	TO
cord-353633-a4pu6rlu	122	11	be	be	VB
cord-353633-a4pu6rlu	122	12	theoretically	theoretically	RB
cord-353633-a4pu6rlu	122	13	a	a	DT
cord-353633-a4pu6rlu	122	14	very	very	RB
cord-353633-a4pu6rlu	122	15	attractive	attractive	JJ
cord-353633-a4pu6rlu	122	16	option	option	NN
cord-353633-a4pu6rlu	122	17	for	for	IN
cord-353633-a4pu6rlu	122	18	a	a	DT
cord-353633-a4pu6rlu	122	19	number	number	NN
cord-353633-a4pu6rlu	122	20	of	of	IN
cord-353633-a4pu6rlu	122	21	reasons	reason	NNS
cord-353633-a4pu6rlu	122	22	.	.	.
cord-353633-a4pu6rlu	123	1	First	first	RB
cord-353633-a4pu6rlu	123	2	,	,	,
cord-353633-a4pu6rlu	123	3	epigenomic	epigenomic	JJ
cord-353633-a4pu6rlu	123	4	alterations	alteration	NNS
cord-353633-a4pu6rlu	123	5	are	be	VBP
cord-353633-a4pu6rlu	123	6	involved	involve	VBN
cord-353633-a4pu6rlu	123	7	in	in	IN
cord-353633-a4pu6rlu	123	8	fundamental	fundamental	JJ
cord-353633-a4pu6rlu	123	9	pathophysiological	pathophysiological	JJ
cord-353633-a4pu6rlu	123	10	mechanisms	mechanism	NNS
cord-353633-a4pu6rlu	123	11	of	of	IN
cord-353633-a4pu6rlu	123	12	a	a	DT
cord-353633-a4pu6rlu	123	13	disease	disease	NN
cord-353633-a4pu6rlu	123	14	through	through	IN
cord-353633-a4pu6rlu	123	15	their	-PRON-	PRP$
cord-353633-a4pu6rlu	123	16	impact	impact	NN
cord-353633-a4pu6rlu	123	17	on	on	IN
cord-353633-a4pu6rlu	123	18	gene	gene	NN
cord-353633-a4pu6rlu	123	19	expression	expression	NN
cord-353633-a4pu6rlu	123	20	.	.	.
cord-353633-a4pu6rlu	124	1	Second	second	JJ
cord-353633-a4pu6rlu	124	2	,	,	,
cord-353633-a4pu6rlu	124	3	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	124	4	changes	change	NNS
cord-353633-a4pu6rlu	124	5	are	be	VBP
cord-353633-a4pu6rlu	124	6	also	also	RB
cord-353633-a4pu6rlu	124	7	highly	highly	RB
cord-353633-a4pu6rlu	124	8	dynamic	dynamic	JJ
cord-353633-a4pu6rlu	124	9	and	and	CC
cord-353633-a4pu6rlu	124	10	reversible	reversible	JJ
cord-353633-a4pu6rlu	124	11	,	,	,
cord-353633-a4pu6rlu	124	12	thus	thus	RB
cord-353633-a4pu6rlu	124	13	correction	correction	NN
cord-353633-a4pu6rlu	124	14	of	of	IN
cord-353633-a4pu6rlu	124	15	them	-PRON-	PRP
cord-353633-a4pu6rlu	124	16	holds	hold	VBZ
cord-353633-a4pu6rlu	124	17	promise	promise	NN
cord-353633-a4pu6rlu	124	18	for	for	IN
cord-353633-a4pu6rlu	124	19	reversal	reversal	NN
cord-353633-a4pu6rlu	124	20	to	to	IN
cord-353633-a4pu6rlu	124	21	"	"	``
cord-353633-a4pu6rlu	124	22	normal	normal	JJ
cord-353633-a4pu6rlu	124	23	status	status	NN
cord-353633-a4pu6rlu	124	24	"	"	''
cord-353633-a4pu6rlu	124	25	.	.	.
cord-353633-a4pu6rlu	125	1	For	for	IN
cord-353633-a4pu6rlu	125	2	example	example	NN
cord-353633-a4pu6rlu	125	3	,	,	,
cord-353633-a4pu6rlu	125	4	after	after	IN
cord-353633-a4pu6rlu	125	5	bariatric	bariatric	JJ
cord-353633-a4pu6rlu	125	6	surgery	surgery	NN
cord-353633-a4pu6rlu	125	7	,	,	,
cord-353633-a4pu6rlu	125	8	robust	robust	JJ
cord-353633-a4pu6rlu	125	9	changes	change	NNS
cord-353633-a4pu6rlu	125	10	in	in	IN
cord-353633-a4pu6rlu	125	11	methylation	methylation	NN
cord-353633-a4pu6rlu	125	12	have	have	VBP
cord-353633-a4pu6rlu	125	13	been	be	VBN
cord-353633-a4pu6rlu	125	14	reported	report	VBN
cord-353633-a4pu6rlu	125	15	.	.	.
cord-353633-a4pu6rlu	126	1	Hypermethylation	Hypermethylation	NNP
cord-353633-a4pu6rlu	126	2	and	and	CC
cord-353633-a4pu6rlu	126	3	consequently	consequently	RB
cord-353633-a4pu6rlu	126	4	reduction	reduction	NN
cord-353633-a4pu6rlu	126	5	of	of	IN
cord-353633-a4pu6rlu	126	6	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	126	7	activity	activity	NN
cord-353633-a4pu6rlu	126	8	of	of	IN
cord-353633-a4pu6rlu	126	9	PTPRE	PTPRE	NNP
cord-353633-a4pu6rlu	127	1	(	(	-LRB-
cord-353633-a4pu6rlu	127	2	encoding	encode	VBG
cord-353633-a4pu6rlu	127	3	protein	protein	NN
cord-353633-a4pu6rlu	127	4	-	-	HYPH
cord-353633-a4pu6rlu	127	5	tyrosine	tyrosine	NN
cord-353633-a4pu6rlu	127	6	phosphatase	phosphatase	NN
cord-353633-a4pu6rlu	127	7	epsilon	epsilon	NN
cord-353633-a4pu6rlu	127	8	)	)	-RRB-
cord-353633-a4pu6rlu	127	9	may	may	MD
cord-353633-a4pu6rlu	127	10	improve	improve	VB
cord-353633-a4pu6rlu	127	11	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	127	12	insulin	insulin	NN
cord-353633-a4pu6rlu	127	13	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	127	14	[	[	-LRB-
cord-353633-a4pu6rlu	127	15	57	57	CD
cord-353633-a4pu6rlu	127	16	]	]	-RRB-
cord-353633-a4pu6rlu	127	17	.	.	.
cord-353633-a4pu6rlu	128	1	Exercise	exercise	NN
cord-353633-a4pu6rlu	128	2	may	may	MD
cord-353633-a4pu6rlu	128	3	also	also	RB
cord-353633-a4pu6rlu	128	4	reduce	reduce	VB
cord-353633-a4pu6rlu	128	5	methylation	methylation	NN
cord-353633-a4pu6rlu	128	6	and	and	CC
cord-353633-a4pu6rlu	128	7	improve	improve	VB
cord-353633-a4pu6rlu	128	8	mRNA	mrna	NN
cord-353633-a4pu6rlu	128	9	levels	level	NNS
cord-353633-a4pu6rlu	128	10	of	of	IN
cord-353633-a4pu6rlu	128	11	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	128	12	genes	gene	NNS
cord-353633-a4pu6rlu	128	13	,	,	,
cord-353633-a4pu6rlu	128	14	thus	thus	RB
cord-353633-a4pu6rlu	128	15	improving	improve	VBG
cord-353633-a4pu6rlu	128	16	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	128	17	function	function	NN
cord-353633-a4pu6rlu	128	18	[	[	-LRB-
cord-353633-a4pu6rlu	128	19	59	59	CD
cord-353633-a4pu6rlu	128	20	]	]	-RRB-
cord-353633-a4pu6rlu	128	21	.	.	.
cord-353633-a4pu6rlu	129	1	Third	third	RB
cord-353633-a4pu6rlu	129	2	,	,	,
cord-353633-a4pu6rlu	129	3	it	-PRON-	PRP
cord-353633-a4pu6rlu	129	4	may	may	MD
cord-353633-a4pu6rlu	129	5	be	be	VB
cord-353633-a4pu6rlu	129	6	possible	possible	JJ
cord-353633-a4pu6rlu	129	7	to	to	TO
cord-353633-a4pu6rlu	129	8	combine	combine	VB
cord-353633-a4pu6rlu	129	9	treatments	treatment	NNS
cord-353633-a4pu6rlu	129	10	targeting	target	VBG
cord-353633-a4pu6rlu	129	11	epigenome	epigenome	NN
cord-353633-a4pu6rlu	129	12	with	with	IN
cord-353633-a4pu6rlu	129	13	other	other	JJ
cord-353633-a4pu6rlu	129	14	drugs	drug	NNS
cord-353633-a4pu6rlu	129	15	,	,	,
cord-353633-a4pu6rlu	129	16	having	have	VBG
cord-353633-a4pu6rlu	129	17	in	in	IN
cord-353633-a4pu6rlu	129	18	that	that	DT
cord-353633-a4pu6rlu	129	19	case	case	NN
cord-353633-a4pu6rlu	129	20	a	a	DT
cord-353633-a4pu6rlu	129	21	complementary	complementary	JJ
cord-353633-a4pu6rlu	129	22	role	role	NN
cord-353633-a4pu6rlu	129	23	.	.	.
cord-353633-a4pu6rlu	130	1	Such	such	JJ
cord-353633-a4pu6rlu	130	2	treatments	treatment	NNS
cord-353633-a4pu6rlu	130	3	are	be	VBP
cord-353633-a4pu6rlu	130	4	currently	currently	RB
cord-353633-a4pu6rlu	130	5	being	be	VBG
cord-353633-a4pu6rlu	130	6	developed	develop	VBN
cord-353633-a4pu6rlu	130	7	mainly	mainly	RB
cord-353633-a4pu6rlu	130	8	against	against	IN
cord-353633-a4pu6rlu	130	9	cancer	cancer	NN
cord-353633-a4pu6rlu	130	10	diseases	disease	NNS
cord-353633-a4pu6rlu	130	11	and	and	CC
cord-353633-a4pu6rlu	130	12	consist	consist	VBP
cord-353633-a4pu6rlu	130	13	of	of	IN
cord-353633-a4pu6rlu	130	14	pharmacological	pharmacological	JJ
cord-353633-a4pu6rlu	130	15	DNA	dna	NN
cord-353633-a4pu6rlu	130	16	methylation	methylation	NN
cord-353633-a4pu6rlu	130	17	inhibitors	inhibitor	NNS
cord-353633-a4pu6rlu	130	18	(	(	-LRB-
cord-353633-a4pu6rlu	130	19	DNMTis	dnmtis	JJ
cord-353633-a4pu6rlu	130	20	)	)	-RRB-
cord-353633-a4pu6rlu	130	21	,	,	,
cord-353633-a4pu6rlu	130	22	HDAC	HDAC	NNP
cord-353633-a4pu6rlu	130	23	inhibitors	inhibitor	NNS
cord-353633-a4pu6rlu	130	24	(	(	-LRB-
cord-353633-a4pu6rlu	130	25	HDACis	HDACis	NNP
cord-353633-a4pu6rlu	130	26	)	)	-RRB-
cord-353633-a4pu6rlu	130	27	or	or	CC
cord-353633-a4pu6rlu	130	28	activators	activator	NNS
cord-353633-a4pu6rlu	130	29	.	.	.
cord-353633-a4pu6rlu	131	1	In	in	IN
cord-353633-a4pu6rlu	131	2	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	131	3	very	very	RB
cord-353633-a4pu6rlu	131	4	few	few	JJ
cord-353633-a4pu6rlu	131	5	of	of	IN
cord-353633-a4pu6rlu	131	6	them	-PRON-	PRP
cord-353633-a4pu6rlu	131	7	have	have	VBP
cord-353633-a4pu6rlu	131	8	been	be	VBN
cord-353633-a4pu6rlu	131	9	tested	test	VBN
cord-353633-a4pu6rlu	131	10	so	so	RB
cord-353633-a4pu6rlu	131	11	far	far	RB
cord-353633-a4pu6rlu	131	12	.	.	.
cord-353633-a4pu6rlu	132	1	J	J	NNP
cord-353633-a4pu6rlu	132	2	o	o	NN
cord-353633-a4pu6rlu	132	3	u	u	NN
cord-353633-a4pu6rlu	132	4	r	r	NN
cord-353633-a4pu6rlu	132	5	n	n	NN
cord-353633-a4pu6rlu	132	6	a	a	DT
cord-353633-a4pu6rlu	132	7	l	l	NN
cord-353633-a4pu6rlu	132	8	P	p	NN
cord-353633-a4pu6rlu	132	9	r	r	NN
cord-353633-a4pu6rlu	132	10	e	e	NN
cord-353633-a4pu6rlu	132	11	-p	-p	NN
cord-353633-a4pu6rlu	133	1	r	r	NN
cord-353633-a4pu6rlu	133	2	o	o	NN
cord-353633-a4pu6rlu	133	3	o	o	NN
cord-353633-a4pu6rlu	133	4	f	f	NN
cord-353633-a4pu6rlu	133	5	22	22	CD
cord-353633-a4pu6rlu	134	1	Among	among	IN
cord-353633-a4pu6rlu	134	2	them	-PRON-	PRP
cord-353633-a4pu6rlu	134	3	,	,	,
cord-353633-a4pu6rlu	134	4	the	the	DT
cord-353633-a4pu6rlu	134	5	SIRT1	sirt1	NN
cord-353633-a4pu6rlu	134	6	activator	activator	NN
cord-353633-a4pu6rlu	134	7	,	,	,
cord-353633-a4pu6rlu	134	8	resveratrol	resveratrol	NN
cord-353633-a4pu6rlu	134	9	,	,	,
cord-353633-a4pu6rlu	134	10	improved	improve	VBD
cord-353633-a4pu6rlu	134	11	dyslipidemia	dyslipidemia	NN
cord-353633-a4pu6rlu	134	12	and	and	CC
cord-353633-a4pu6rlu	134	13	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	134	14	in	in	IN
cord-353633-a4pu6rlu	134	15	a	a	DT
cord-353633-a4pu6rlu	134	16	mouse	mouse	NN
cord-353633-a4pu6rlu	134	17	model	model	NN
cord-353633-a4pu6rlu	134	18	of	of	IN
cord-353633-a4pu6rlu	134	19	atherogenic	atherogenic	JJ
cord-353633-a4pu6rlu	134	20	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	134	21	[	[	-LRB-
cord-353633-a4pu6rlu	134	22	82	82	CD
cord-353633-a4pu6rlu	134	23	]	]	-RRB-
cord-353633-a4pu6rlu	134	24	.	.	.
cord-353633-a4pu6rlu	135	1	Several	several	JJ
cord-353633-a4pu6rlu	135	2	ongoing	ongoing	JJ
cord-353633-a4pu6rlu	135	3	human	human	JJ
cord-353633-a4pu6rlu	135	4	clinical	clinical	JJ
cord-353633-a4pu6rlu	135	5	trials	trial	NNS
cord-353633-a4pu6rlu	135	6	(	(	-LRB-
cord-353633-a4pu6rlu	135	7	two	two	CD
cord-353633-a4pu6rlu	135	8	of	of	IN
cord-353633-a4pu6rlu	135	9	them	-PRON-	PRP
cord-353633-a4pu6rlu	135	10	in	in	IN
cord-353633-a4pu6rlu	135	11	Phase	Phase	NNP
cord-353633-a4pu6rlu	135	12	III	III	NNP
cord-353633-a4pu6rlu	135	13	)	)	-RRB-
cord-353633-a4pu6rlu	135	14	are	be	VBP
cord-353633-a4pu6rlu	135	15	currently	currently	RB
cord-353633-a4pu6rlu	135	16	investigating	investigate	VBG
cord-353633-a4pu6rlu	135	17	the	the	DT
cord-353633-a4pu6rlu	135	18	efficacy	efficacy	NN
cord-353633-a4pu6rlu	135	19	of	of	IN
cord-353633-a4pu6rlu	135	20	resveratrol	resveratrol	NN
cord-353633-a4pu6rlu	135	21	in	in	IN
cord-353633-a4pu6rlu	135	22	human	human	JJ
cord-353633-a4pu6rlu	135	23	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	135	24	but	but	CC
cord-353633-a4pu6rlu	135	25	results	result	NNS
cord-353633-a4pu6rlu	135	26	from	from	IN
cord-353633-a4pu6rlu	135	27	the	the	DT
cord-353633-a4pu6rlu	135	28	first	first	JJ
cord-353633-a4pu6rlu	135	29	studies	study	NNS
cord-353633-a4pu6rlu	135	30	have	have	VBP
cord-353633-a4pu6rlu	135	31	shown	show	VBN
cord-353633-a4pu6rlu	135	32	no	no	DT
cord-353633-a4pu6rlu	135	33	significant	significant	JJ
cord-353633-a4pu6rlu	135	34	effect	effect	NN
cord-353633-a4pu6rlu	135	35	on	on	IN
cord-353633-a4pu6rlu	135	36	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	135	37	fat	fat	NN
cord-353633-a4pu6rlu	135	38	content	content	NN
cord-353633-a4pu6rlu	135	39	[	[	-LRB-
cord-353633-a4pu6rlu	135	40	83	83	CD
cord-353633-a4pu6rlu	135	41	]	]	-RRB-
cord-353633-a4pu6rlu	135	42	[	[	-LRB-
cord-353633-a4pu6rlu	135	43	84	84	CD
cord-353633-a4pu6rlu	135	44	]	]	-RRB-
cord-353633-a4pu6rlu	135	45	[	[	-LRB-
cord-353633-a4pu6rlu	135	46	85	85	CD
cord-353633-a4pu6rlu	135	47	]	]	-RRB-
cord-353633-a4pu6rlu	135	48	.	.	.
cord-353633-a4pu6rlu	136	1	Other	other	JJ
cord-353633-a4pu6rlu	136	2	medications	medication	NNS
cord-353633-a4pu6rlu	136	3	are	be	VBP
cord-353633-a4pu6rlu	136	4	currently	currently	RB
cord-353633-a4pu6rlu	136	5	also	also	RB
cord-353633-a4pu6rlu	136	6	being	be	VBG
cord-353633-a4pu6rlu	136	7	developed	develop	VBN
cord-353633-a4pu6rlu	136	8	and	and	CC
cord-353633-a4pu6rlu	136	9	have	have	VBP
cord-353633-a4pu6rlu	136	10	shown	show	VBN
cord-353633-a4pu6rlu	136	11	promising	promising	JJ
cord-353633-a4pu6rlu	136	12	results	result	NNS
cord-353633-a4pu6rlu	136	13	in	in	IN
cord-353633-a4pu6rlu	136	14	animal	animal	NN
cord-353633-a4pu6rlu	136	15	studies	study	NNS
cord-353633-a4pu6rlu	136	16	,	,	,
cord-353633-a4pu6rlu	136	17	such	such	JJ
cord-353633-a4pu6rlu	136	18	as	as	IN
cord-353633-a4pu6rlu	136	19	the	the	DT
cord-353633-a4pu6rlu	136	20	3-deazaneplanocin	3-deazaneplanocin	CD
cord-353633-a4pu6rlu	136	21	A	a	NN
cord-353633-a4pu6rlu	136	22	(	(	-LRB-
cord-353633-a4pu6rlu	136	23	DZNep	DZNep	NNS
cord-353633-a4pu6rlu	136	24	)	)	-RRB-
cord-353633-a4pu6rlu	136	25	[	[	-LRB-
cord-353633-a4pu6rlu	136	26	86	86	CD
cord-353633-a4pu6rlu	136	27	]	]	-RRB-
cord-353633-a4pu6rlu	136	28	or	or	CC
cord-353633-a4pu6rlu	136	29	the	the	DT
cord-353633-a4pu6rlu	136	30	HDAC	HDAC	NNP
cord-353633-a4pu6rlu	136	31	inhibitor	inhibitor	NN
cord-353633-a4pu6rlu	136	32	SAHA	SAHA	NNP
cord-353633-a4pu6rlu	137	1	but	but	CC
cord-353633-a4pu6rlu	137	2	none	none	NN
cord-353633-a4pu6rlu	137	3	of	of	IN
cord-353633-a4pu6rlu	137	4	them	-PRON-	PRP
cord-353633-a4pu6rlu	137	5	is	be	VBZ
cord-353633-a4pu6rlu	137	6	in	in	IN
cord-353633-a4pu6rlu	137	7	a	a	DT
cord-353633-a4pu6rlu	137	8	more	more	RBR
cord-353633-a4pu6rlu	137	9	advanced	advanced	JJ
cord-353633-a4pu6rlu	137	10	stage	stage	NN
cord-353633-a4pu6rlu	137	11	of	of	IN
cord-353633-a4pu6rlu	137	12	clinical	clinical	JJ
cord-353633-a4pu6rlu	137	13	development	development	NN
cord-353633-a4pu6rlu	137	14	[	[	-LRB-
cord-353633-a4pu6rlu	137	15	87	87	CD
cord-353633-a4pu6rlu	137	16	]	]	-RRB-
cord-353633-a4pu6rlu	137	17	.	.	.
cord-353633-a4pu6rlu	138	1	Epigenomics	epigenomic	NNS
cord-353633-a4pu6rlu	138	2	are	be	VBP
cord-353633-a4pu6rlu	138	3	one	one	CD
cord-353633-a4pu6rlu	138	4	of	of	IN
cord-353633-a4pu6rlu	138	5	the	the	DT
cord-353633-a4pu6rlu	138	6	least	least	JJS
cord-353633-a4pu6rlu	138	7	investigated	investigated	JJ
cord-353633-a4pu6rlu	138	8	"	"	``
cord-353633-a4pu6rlu	138	9	omics	omic	NNS
cord-353633-a4pu6rlu	138	10	"	"	''
cord-353633-a4pu6rlu	138	11	in	in	IN
cord-353633-a4pu6rlu	138	12	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	138	13	.	.	.
cord-353633-a4pu6rlu	139	1	The	the	DT
cord-353633-a4pu6rlu	139	2	few	few	JJ
cord-353633-a4pu6rlu	139	3	studies	study	NNS
cord-353633-a4pu6rlu	139	4	performed	perform	VBN
cord-353633-a4pu6rlu	139	5	so	so	RB
cord-353633-a4pu6rlu	139	6	far	far	RB
cord-353633-a4pu6rlu	139	7	have	have	VBP
cord-353633-a4pu6rlu	139	8	shown	show	VBN
cord-353633-a4pu6rlu	139	9	that	that	IN
cord-353633-a4pu6rlu	139	10	the	the	DT
cord-353633-a4pu6rlu	139	11	extensive	extensive	JJ
cord-353633-a4pu6rlu	139	12	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	139	13	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	139	14	modifications	modification	NNS
cord-353633-a4pu6rlu	139	15	observed	observe	VBN
cord-353633-a4pu6rlu	139	16	in	in	IN
cord-353633-a4pu6rlu	139	17	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	139	18	are	be	VBP
cord-353633-a4pu6rlu	139	19	causally	causally	RB
cord-353633-a4pu6rlu	139	20	related	relate	VBN
cord-353633-a4pu6rlu	139	21	to	to	IN
cord-353633-a4pu6rlu	139	22	the	the	DT
cord-353633-a4pu6rlu	139	23	disease	disease	NN
cord-353633-a4pu6rlu	139	24	.	.	.
cord-353633-a4pu6rlu	140	1	It	-PRON-	PRP
cord-353633-a4pu6rlu	140	2	is	be	VBZ
cord-353633-a4pu6rlu	140	3	still	still	RB
cord-353633-a4pu6rlu	140	4	unclear	unclear	JJ
cord-353633-a4pu6rlu	140	5	though	though	IN
cord-353633-a4pu6rlu	140	6	how	how	WRB
cord-353633-a4pu6rlu	140	7	accurately	accurately	RB
cord-353633-a4pu6rlu	140	8	the	the	DT
cord-353633-a4pu6rlu	140	9	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	140	10	epigenome	epigenome	NN
cord-353633-a4pu6rlu	140	11	is	be	VBZ
cord-353633-a4pu6rlu	140	12	reflected	reflect	VBN
cord-353633-a4pu6rlu	140	13	in	in	IN
cord-353633-a4pu6rlu	140	14	peripheral	peripheral	JJ
cord-353633-a4pu6rlu	140	15	blood	blood	NN
cord-353633-a4pu6rlu	140	16	and	and	CC
cord-353633-a4pu6rlu	140	17	thus	thus	RB
cord-353633-a4pu6rlu	140	18	it	-PRON-	PRP
cord-353633-a4pu6rlu	140	19	is	be	VBZ
cord-353633-a4pu6rlu	140	20	questionable	questionable	JJ
cord-353633-a4pu6rlu	140	21	whether	whether	IN
cord-353633-a4pu6rlu	140	22	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	140	23	changes	change	NNS
cord-353633-a4pu6rlu	140	24	studied	study	VBD
cord-353633-a4pu6rlu	140	25	at	at	IN
cord-353633-a4pu6rlu	140	26	the	the	DT
cord-353633-a4pu6rlu	140	27	level	level	NN
cord-353633-a4pu6rlu	140	28	of	of	IN
cord-353633-a4pu6rlu	140	29	peripheral	peripheral	JJ
cord-353633-a4pu6rlu	140	30	blood	blood	NN
cord-353633-a4pu6rlu	140	31	cells	cell	NNS
cord-353633-a4pu6rlu	140	32	may	may	MD
cord-353633-a4pu6rlu	140	33	have	have	VB
cord-353633-a4pu6rlu	140	34	any	any	DT
cord-353633-a4pu6rlu	140	35	significant	significant	JJ
cord-353633-a4pu6rlu	140	36	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	140	37	value	value	NN
cord-353633-a4pu6rlu	140	38	.	.	.
cord-353633-a4pu6rlu	141	1	Given	give	VBN
cord-353633-a4pu6rlu	141	2	also	also	RB
cord-353633-a4pu6rlu	141	3	the	the	DT
cord-353633-a4pu6rlu	141	4	limited	limited	JJ
cord-353633-a4pu6rlu	141	5	amount	amount	NN
cord-353633-a4pu6rlu	141	6	of	of	IN
cord-353633-a4pu6rlu	141	7	information	information	NN
cord-353633-a4pu6rlu	141	8	from	from	IN
cord-353633-a4pu6rlu	141	9	pathophysiological	pathophysiological	JJ
cord-353633-a4pu6rlu	141	10	studies	study	NNS
cord-353633-a4pu6rlu	141	11	investigating	investigate	VBG
cord-353633-a4pu6rlu	141	12	the	the	DT
cord-353633-a4pu6rlu	141	13	dynamic	dynamic	JJ
cord-353633-a4pu6rlu	141	14	of	of	IN
cord-353633-a4pu6rlu	141	15	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	141	16	changes	change	NNS
cord-353633-a4pu6rlu	141	17	with	with	IN
cord-353633-a4pu6rlu	141	18	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	141	19	development	development	NN
cord-353633-a4pu6rlu	141	20	and	and	CC
cord-353633-a4pu6rlu	141	21	progression	progression	NN
cord-353633-a4pu6rlu	141	22	,	,	,
cord-353633-a4pu6rlu	141	23	it	-PRON-	PRP
cord-353633-a4pu6rlu	141	24	is	be	VBZ
cord-353633-a4pu6rlu	141	25	probably	probably	RB
cord-353633-a4pu6rlu	141	26	premature	premature	JJ
cord-353633-a4pu6rlu	141	27	to	to	TO
cord-353633-a4pu6rlu	141	28	expect	expect	VB
cord-353633-a4pu6rlu	141	29	any	any	DT
cord-353633-a4pu6rlu	141	30	drugs	drug	NNS
cord-353633-a4pu6rlu	141	31	to	to	TO
cord-353633-a4pu6rlu	141	32	be	be	VB
cord-353633-a4pu6rlu	141	33	developed	develop	VBN
cord-353633-a4pu6rlu	141	34	in	in	IN
cord-353633-a4pu6rlu	141	35	order	order	NN
cord-353633-a4pu6rlu	141	36	to	to	TO
cord-353633-a4pu6rlu	141	37	target	target	VB
cord-353633-a4pu6rlu	141	38	exclusively	exclusively	RB
cord-353633-a4pu6rlu	141	39	epigenome	epigenome	NN
cord-353633-a4pu6rlu	141	40	of	of	IN
cord-353633-a4pu6rlu	141	41	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	141	42	in	in	IN
cord-353633-a4pu6rlu	141	43	the	the	DT
cord-353633-a4pu6rlu	141	44	near	near	JJ
cord-353633-a4pu6rlu	141	45	future	future	NN
cord-353633-a4pu6rlu	141	46	.	.	.
cord-353633-a4pu6rlu	141	47	 	 	_SP
cord-353633-a4pu6rlu	142	1	Genetic	genetic	JJ
cord-353633-a4pu6rlu	142	2	predisposition	predisposition	NN
cord-353633-a4pu6rlu	142	3	determines	determine	VBZ
cord-353633-a4pu6rlu	142	4	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	142	5	transcriptomic	transcriptomic	JJ
cord-353633-a4pu6rlu	142	6	signatures	signature	NNS
cord-353633-a4pu6rlu	142	7	,	,	,
cord-353633-a4pu6rlu	142	8	as	as	IN
cord-353633-a4pu6rlu	142	9	shown	show	VBN
cord-353633-a4pu6rlu	142	10	by	by	IN
cord-353633-a4pu6rlu	142	11	recent	recent	JJ
cord-353633-a4pu6rlu	142	12	investigations	investigation	NNS
cord-353633-a4pu6rlu	142	13	on	on	IN
cord-353633-a4pu6rlu	142	14	the	the	DT
cord-353633-a4pu6rlu	142	15	carriage	carriage	NN
cord-353633-a4pu6rlu	142	16	of	of	IN
cord-353633-a4pu6rlu	142	17	PNPLA3	PNPLA3	NNP
cord-353633-a4pu6rlu	142	18	I148	I148	NNP
cord-353633-a4pu6rlu	142	19	M	M	NNP
cord-353633-a4pu6rlu	142	20	on	on	IN
cord-353633-a4pu6rlu	142	21	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	142	22	variability	variability	NN
cord-353633-a4pu6rlu	142	23	[	[	-LRB-
cord-353633-a4pu6rlu	142	24	88	88	CD
cord-353633-a4pu6rlu	142	25	]	]	-RRB-
cord-353633-a4pu6rlu	142	26	.	.	.
cord-353633-a4pu6rlu	143	1	As	as	IN
cord-353633-a4pu6rlu	143	2	described	describe	VBN
cord-353633-a4pu6rlu	143	3	above	above	RB
cord-353633-a4pu6rlu	143	4	,	,	,
cord-353633-a4pu6rlu	143	5	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	143	6	are	be	VBP
cord-353633-a4pu6rlu	143	7	also	also	RB
cord-353633-a4pu6rlu	143	8	linked	link	VBN
cord-353633-a4pu6rlu	143	9	to	to	IN
cord-353633-a4pu6rlu	143	10	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	143	11	modifications	modification	NNS
cord-353633-a4pu6rlu	143	12	in	in	IN
cord-353633-a4pu6rlu	143	13	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	143	14	[	[	-LRB-
cord-353633-a4pu6rlu	143	15	56	56	CD
cord-353633-a4pu6rlu	143	16	,	,	,
cord-353633-a4pu6rlu	143	17	57	57	CD
cord-353633-a4pu6rlu	143	18	]	]	-RRB-
cord-353633-a4pu6rlu	143	19	.	.	.
cord-353633-a4pu6rlu	144	1	Through	through	IN
cord-353633-a4pu6rlu	144	2	global	global	JJ
cord-353633-a4pu6rlu	144	3	microarray	microarray	NN
cord-353633-a4pu6rlu	144	4	transcriptional	transcriptional	NN
cord-353633-a4pu6rlu	144	5	snapshots	snapshot	NNS
cord-353633-a4pu6rlu	144	6	,	,	,
cord-353633-a4pu6rlu	144	7	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	144	8	and	and	CC
cord-353633-a4pu6rlu	144	9	especially	especially	RB
cord-353633-a4pu6rlu	144	10	NASH	NASH	NNP
cord-353633-a4pu6rlu	144	11	are	be	VBP
cord-353633-a4pu6rlu	144	12	characterized	characterize	VBN
cord-353633-a4pu6rlu	144	13	by	by	IN
cord-353633-a4pu6rlu	144	14	overexpression	overexpression	NN
cord-353633-a4pu6rlu	144	15	of	of	IN
cord-353633-a4pu6rlu	144	16	genes	gene	NNS
cord-353633-a4pu6rlu	144	17	associated	associate	VBN
cord-353633-a4pu6rlu	144	18	with	with	IN
cord-353633-a4pu6rlu	144	19	lipid	lipid	NN
cord-353633-a4pu6rlu	144	20	metabolism	metabolism	NN
cord-353633-a4pu6rlu	144	21	[	[	-LRB-
cord-353633-a4pu6rlu	144	22	89	89	CD
cord-353633-a4pu6rlu	144	23	]	]	-RRB-
cord-353633-a4pu6rlu	144	24	[	[	-LRB-
cord-353633-a4pu6rlu	144	25	90	90	CD
cord-353633-a4pu6rlu	144	26	]	]	-RRB-
cord-353633-a4pu6rlu	144	27	[	[	-LRB-
cord-353633-a4pu6rlu	144	28	91	91	CD
cord-353633-a4pu6rlu	144	29	]	]	-RRB-
cord-353633-a4pu6rlu	144	30	[	[	-LRB-
cord-353633-a4pu6rlu	144	31	92	92	CD
cord-353633-a4pu6rlu	144	32	]	]	-RRB-
cord-353633-a4pu6rlu	144	33	,	,	,
cord-353633-a4pu6rlu	144	34	acute	acute	JJ
cord-353633-a4pu6rlu	144	35	phase	phase	NN
cord-353633-a4pu6rlu	144	36	regulators	regulator	NNS
cord-353633-a4pu6rlu	144	37	of	of	IN
cord-353633-a4pu6rlu	144	38	insulin	insulin	NN
cord-353633-a4pu6rlu	144	39	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	144	40	[	[	-LRB-
cord-353633-a4pu6rlu	144	41	93	93	CD
cord-353633-a4pu6rlu	144	42	]	]	-RRB-
cord-353633-a4pu6rlu	144	43	,	,	,
cord-353633-a4pu6rlu	144	44	cellular	cellular	JJ
cord-353633-a4pu6rlu	144	45	division	division	NN
cord-353633-a4pu6rlu	144	46	[	[	-LRB-
cord-353633-a4pu6rlu	144	47	89	89	CD
cord-353633-a4pu6rlu	144	48	]	]	-RRB-
cord-353633-a4pu6rlu	144	49	,	,	,
cord-353633-a4pu6rlu	144	50	DNA	DNA	NNP
cord-353633-a4pu6rlu	144	51	[	[	-LRB-
cord-353633-a4pu6rlu	144	52	89	89	CD
cord-353633-a4pu6rlu	144	53	]	]	-RRB-
cord-353633-a4pu6rlu	144	54	and	and	CC
cord-353633-a4pu6rlu	144	55	tissue	tissue	NN
cord-353633-a4pu6rlu	144	56	repair	repair	NN
cord-353633-a4pu6rlu	144	57	[	[	-LRB-
cord-353633-a4pu6rlu	144	58	56	56	CD
cord-353633-a4pu6rlu	144	59	]	]	-RRB-
cord-353633-a4pu6rlu	144	60	,	,	,
cord-353633-a4pu6rlu	144	61	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	144	62	matrix	matrix	NN
cord-353633-a4pu6rlu	144	63	organization	organization	NN
cord-353633-a4pu6rlu	144	64	[	[	-LRB-
cord-353633-a4pu6rlu	144	65	91	91	CD
cord-353633-a4pu6rlu	144	66	,	,	,
cord-353633-a4pu6rlu	144	67	[	[	-LRB-
cord-353633-a4pu6rlu	144	68	94	94	CD
cord-353633-a4pu6rlu	144	69	]	]	-RRB-
cord-353633-a4pu6rlu	144	70	[	[	-LRB-
cord-353633-a4pu6rlu	144	71	95	95	CD
cord-353633-a4pu6rlu	144	72	]	]	-RRB-
cord-353633-a4pu6rlu	144	73	[	[	-LRB-
cord-353633-a4pu6rlu	144	74	96	96	CD
cord-353633-a4pu6rlu	144	75	]	]	-RRB-
cord-353633-a4pu6rlu	144	76	,	,	,
cord-353633-a4pu6rlu	144	77	immune	immune	JJ
cord-353633-a4pu6rlu	144	78	function	function	NN
cord-353633-a4pu6rlu	144	79	[	[	-LRB-
cord-353633-a4pu6rlu	144	80	95	95	CD
cord-353633-a4pu6rlu	144	81	]	]	-RRB-
cord-353633-a4pu6rlu	144	82	cellular	cellular	JJ
cord-353633-a4pu6rlu	144	83	adhesion	adhesion	NN
cord-353633-a4pu6rlu	144	84	and	and	CC
cord-353633-a4pu6rlu	144	85	migration	migration	NN
cord-353633-a4pu6rlu	144	86	[	[	-LRB-
cord-353633-a4pu6rlu	144	87	91	91	CD
cord-353633-a4pu6rlu	144	88	,	,	,
cord-353633-a4pu6rlu	144	89	92	92	CD
cord-353633-a4pu6rlu	144	90	,	,	,
cord-353633-a4pu6rlu	144	91	96	96	CD
cord-353633-a4pu6rlu	144	92	]	]	-RRB-
cord-353633-a4pu6rlu	144	93	,	,	,
cord-353633-a4pu6rlu	144	94	signal	signal	NN
cord-353633-a4pu6rlu	144	95	transduction	transduction	NN
cord-353633-a4pu6rlu	144	96	[	[	-LRB-
cord-353633-a4pu6rlu	144	97	91	91	CD
cord-353633-a4pu6rlu	144	98	]	]	-RRB-
cord-353633-a4pu6rlu	144	99	,	,	,
cord-353633-a4pu6rlu	144	100	P53	P53	NNP
cord-353633-a4pu6rlu	144	101	signaling	signal	VBG
cord-353633-a4pu6rlu	144	102	[	[	-LRB-
cord-353633-a4pu6rlu	144	103	92	92	CD
cord-353633-a4pu6rlu	144	104	]	]	-RRB-
cord-353633-a4pu6rlu	144	105	and	and	CC
cord-353633-a4pu6rlu	144	106	cancer	cancer	NN
cord-353633-a4pu6rlu	144	107	progression	progression	NN
cord-353633-a4pu6rlu	144	108	[	[	-LRB-
cord-353633-a4pu6rlu	144	109	96	96	CD
cord-353633-a4pu6rlu	144	110	]	]	-RRB-
cord-353633-a4pu6rlu	144	111	among	among	IN
cord-353633-a4pu6rlu	144	112	others	other	NNS
cord-353633-a4pu6rlu	144	113	(	(	-LRB-
cord-353633-a4pu6rlu	144	114	Figure	figure	NN
cord-353633-a4pu6rlu	144	115	2	2	CD
cord-353633-a4pu6rlu	144	116	)	)	-RRB-
cord-353633-a4pu6rlu	144	117	.	.	.
cord-353633-a4pu6rlu	145	1	Conversely	conversely	RB
cord-353633-a4pu6rlu	145	2	,	,	,
cord-353633-a4pu6rlu	145	3	genes	gene	NNS
cord-353633-a4pu6rlu	145	4	modulating	modulate	VBG
cord-353633-a4pu6rlu	145	5	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	145	6	function	function	NN
cord-353633-a4pu6rlu	145	7	[	[	-LRB-
cord-353633-a4pu6rlu	145	8	93	93	CD
cord-353633-a4pu6rlu	145	9	]	]	-RRB-
cord-353633-a4pu6rlu	145	10	oxidative	oxidative	JJ
cord-353633-a4pu6rlu	145	11	,	,	,
cord-353633-a4pu6rlu	145	12	glucose	glucose	NN
cord-353633-a4pu6rlu	145	13	,	,	,
cord-353633-a4pu6rlu	145	14	fatty	fatty	JJ
cord-353633-a4pu6rlu	145	15	acid	acid	NN
cord-353633-a4pu6rlu	145	16	and	and	CC
cord-353633-a4pu6rlu	145	17	aminoacid	aminoacid	JJ
cord-353633-a4pu6rlu	145	18	or	or	CC
cord-353633-a4pu6rlu	145	19	protein	protein	NN
cord-353633-a4pu6rlu	145	20	metabolism	metabolism	NN
cord-353633-a4pu6rlu	145	21	[	[	-LRB-
cord-353633-a4pu6rlu	145	22	56	56	CD
cord-353633-a4pu6rlu	145	23	,	,	,
cord-353633-a4pu6rlu	145	24	91	91	CD
cord-353633-a4pu6rlu	145	25	-	-	SYM
cord-353633-a4pu6rlu	145	26	93	93	CD
cord-353633-a4pu6rlu	145	27	,	,	,
cord-353633-a4pu6rlu	145	28	96	96	CD
cord-353633-a4pu6rlu	145	29	,	,	,
cord-353633-a4pu6rlu	145	30	97	97	CD
cord-353633-a4pu6rlu	145	31	]	]	-RRB-
cord-353633-a4pu6rlu	145	32	as	as	RB
cord-353633-a4pu6rlu	145	33	well	well	RB
cord-353633-a4pu6rlu	145	34	as	as	IN
cord-353633-a4pu6rlu	145	35	insulin	insulin	NN
cord-353633-a4pu6rlu	145	36	signaling	signaling	NN
cord-353633-a4pu6rlu	145	37	and	and	CC
cord-353633-a4pu6rlu	145	38	transcription	transcription	NN
cord-353633-a4pu6rlu	145	39	factors	factor	NNS
cord-353633-a4pu6rlu	145	40	[	[	-LRB-
cord-353633-a4pu6rlu	145	41	91	91	CD
cord-353633-a4pu6rlu	145	42	,	,	,
cord-353633-a4pu6rlu	145	43	94	94	CD
cord-353633-a4pu6rlu	145	44	]	]	-RRB-
cord-353633-a4pu6rlu	145	45	are	be	VBP
cord-353633-a4pu6rlu	145	46	downregulated	downregulate	VBN
cord-353633-a4pu6rlu	145	47	.	.	.
cord-353633-a4pu6rlu	146	1	and	and	CC
cord-353633-a4pu6rlu	146	2	underexpression	underexpression	NN
cord-353633-a4pu6rlu	146	3	of	of	IN
cord-353633-a4pu6rlu	146	4	PZP	PZP	NNP
cord-353633-a4pu6rlu	146	5	mRNAs	mrnas	XX
cord-353633-a4pu6rlu	146	6	[	[	-LRB-
cord-353633-a4pu6rlu	146	7	92	92	CD
cord-353633-a4pu6rlu	146	8	]	]	-RRB-
cord-353633-a4pu6rlu	146	9	.	.	.
cord-353633-a4pu6rlu	147	1	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	147	2	transcriptomes	transcriptome	NNS
cord-353633-a4pu6rlu	147	3	of	of	IN
cord-353633-a4pu6rlu	147	4	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	147	5	are	be	VBP
cord-353633-a4pu6rlu	147	6	distinct	distinct	JJ
cord-353633-a4pu6rlu	147	7	from	from	IN
cord-353633-a4pu6rlu	147	8	those	those	DT
cord-353633-a4pu6rlu	147	9	of	of	IN
cord-353633-a4pu6rlu	147	10	normal	normal	JJ
cord-353633-a4pu6rlu	147	11	and	and	CC
cord-353633-a4pu6rlu	147	12	healthy	healthy	JJ
cord-353633-a4pu6rlu	147	13	obese	obese	JJ
cord-353633-a4pu6rlu	147	14	subjects	subject	NNS
cord-353633-a4pu6rlu	147	15	,	,	,
cord-353633-a4pu6rlu	147	16	yet	yet	CC
cord-353633-a4pu6rlu	147	17	a	a	DT
cord-353633-a4pu6rlu	147	18	132-gene	132-gene	CD
cord-353633-a4pu6rlu	147	19	signature	signature	NN
cord-353633-a4pu6rlu	147	20	,	,	,
cord-353633-a4pu6rlu	147	21	with	with	IN
cord-353633-a4pu6rlu	147	22	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	147	23	matrix	matrix	NN
cord-353633-a4pu6rlu	147	24	remodeling	remodeling	NN
cord-353633-a4pu6rlu	147	25	and	and	CC
cord-353633-a4pu6rlu	147	26	immune	immune	JJ
cord-353633-a4pu6rlu	147	27	system	system	NN
cord-353633-a4pu6rlu	147	28	genes	gene	NNS
cord-353633-a4pu6rlu	147	29	as	as	IN
cord-353633-a4pu6rlu	147	30	its	-PRON-	PRP$
cord-353633-a4pu6rlu	147	31	main	main	JJ
cord-353633-a4pu6rlu	147	32	components	component	NNS
cord-353633-a4pu6rlu	147	33	,	,	,
cord-353633-a4pu6rlu	147	34	distinguishes	distinguish	VBZ
cord-353633-a4pu6rlu	147	35	NASH	NASH	NNP
cord-353633-a4pu6rlu	147	36	from	from	IN
cord-353633-a4pu6rlu	147	37	simple	simple	JJ
cord-353633-a4pu6rlu	147	38	steatosis	steatosis	NN
cord-353633-a4pu6rlu	147	39	[	[	-LRB-
cord-353633-a4pu6rlu	147	40	95	95	CD
cord-353633-a4pu6rlu	147	41	]	]	-RRB-
cord-353633-a4pu6rlu	147	42	.	.	.
cord-353633-a4pu6rlu	148	1	More	more	RBR
cord-353633-a4pu6rlu	148	2	specifically	specifically	RB
cord-353633-a4pu6rlu	148	3	,	,	,
cord-353633-a4pu6rlu	148	4	the	the	DT
cord-353633-a4pu6rlu	148	5	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	148	6	snapshot	snapshot	NN
cord-353633-a4pu6rlu	148	7	of	of	IN
cord-353633-a4pu6rlu	148	8	NASH	NASH	NNP
cord-353633-a4pu6rlu	148	9	is	be	VBZ
cord-353633-a4pu6rlu	148	10	defined	define	VBN
cord-353633-a4pu6rlu	148	11	by	by	IN
cord-353633-a4pu6rlu	148	12	upregulation	upregulation	NN
cord-353633-a4pu6rlu	148	13	of	of	IN
cord-353633-a4pu6rlu	148	14	PDGF	PDGF	NNP
cord-353633-a4pu6rlu	148	15	,	,	,
cord-353633-a4pu6rlu	148	16	STAT	stat	NN
cord-353633-a4pu6rlu	148	17	,	,	,
cord-353633-a4pu6rlu	148	18	HNF-3	HNF-3	NNP
cord-353633-a4pu6rlu	148	19	and	and	CC
cord-353633-a4pu6rlu	148	20	SMAD-4	SMAD-4	NNP
cord-353633-a4pu6rlu	148	21	pathway	pathway	NN
cord-353633-a4pu6rlu	148	22	-	-	HYPH
cord-353633-a4pu6rlu	148	23	related	relate	VBN
cord-353633-a4pu6rlu	148	24	genes	gene	NNS
cord-353633-a4pu6rlu	148	25	[	[	-LRB-
cord-353633-a4pu6rlu	148	26	97	97	CD
cord-353633-a4pu6rlu	148	27	]	]	-RRB-
cord-353633-a4pu6rlu	148	28	,	,	,
cord-353633-a4pu6rlu	148	29	as	as	RB
cord-353633-a4pu6rlu	148	30	well	well	RB
cord-353633-a4pu6rlu	148	31	as	as	IN
cord-353633-a4pu6rlu	148	32	downregulation	downregulation	NN
cord-353633-a4pu6rlu	148	33	of	of	IN
cord-353633-a4pu6rlu	148	34	BNIP1	bnip1	NN
cord-353633-a4pu6rlu	148	35	,	,	,
cord-353633-a4pu6rlu	148	36	IGFBP1	IGFBP1	VBZ
cord-353633-a4pu6rlu	148	37	[	[	-LRB-
cord-353633-a4pu6rlu	148	38	97	97	CD
cord-353633-a4pu6rlu	148	39	]	]	-RRB-
cord-353633-a4pu6rlu	148	40	,	,	,
cord-353633-a4pu6rlu	148	41	SLC25A48	SLC25A48	NNP
cord-353633-a4pu6rlu	148	42	,	,	,
cord-353633-a4pu6rlu	148	43	C4ORF48	c4orf48	JJ
cord-353633-a4pu6rlu	148	44	[	[	-LRB-
cord-353633-a4pu6rlu	148	45	95	95	CD
cord-353633-a4pu6rlu	148	46	]	]	-RRB-
cord-353633-a4pu6rlu	149	1	SDC4	SDC4	NNP
cord-353633-a4pu6rlu	149	2	,	,	,
cord-353633-a4pu6rlu	149	3	ATF3	ATF3	NNP
cord-353633-a4pu6rlu	149	4	,	,	,
cord-353633-a4pu6rlu	149	5	various	various	JJ
cord-353633-a4pu6rlu	149	6	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	149	7	suppressors	suppressor	NNS
cord-353633-a4pu6rlu	149	8	[	[	-LRB-
cord-353633-a4pu6rlu	149	9	94	94	CD
cord-353633-a4pu6rlu	149	10	]	]	-RRB-
cord-353633-a4pu6rlu	149	11	and	and	CC
cord-353633-a4pu6rlu	149	12	amino	amino	NN
cord-353633-a4pu6rlu	149	13	acid	acid	NN
cord-353633-a4pu6rlu	149	14	-	-	HYPH
cord-353633-a4pu6rlu	149	15	metabolizing	metabolize	VBG
cord-353633-a4pu6rlu	149	16	and	and	CC
cord-353633-a4pu6rlu	149	17	reactive	reactive	JJ
cord-353633-a4pu6rlu	149	18	oxygen	oxygen	NN
cord-353633-a4pu6rlu	149	19	species	specie	NNS
cord-353633-a4pu6rlu	149	20	(	(	-LRB-
cord-353633-a4pu6rlu	149	21	ROS	ROS	NNP
cord-353633-a4pu6rlu	149	22	)	)	-RRB-
cord-353633-a4pu6rlu	149	23	scavenger	scavenger	NN
cord-353633-a4pu6rlu	149	24	genes	gene	NNS
cord-353633-a4pu6rlu	149	25	[	[	-LRB-
cord-353633-a4pu6rlu	149	26	97	97	CD
cord-353633-a4pu6rlu	149	27	]	]	-RRB-
cord-353633-a4pu6rlu	149	28	.	.	.
cord-353633-a4pu6rlu	150	1	Interleukin-32	Interleukin-32	NNP
cord-353633-a4pu6rlu	150	2	(	(	-LRB-
cord-353633-a4pu6rlu	150	3	IL-32	IL-32	NNP
cord-353633-a4pu6rlu	150	4	)	)	-RRB-
cord-353633-a4pu6rlu	150	5	was	be	VBD
cord-353633-a4pu6rlu	150	6	recently	recently	RB
cord-353633-a4pu6rlu	150	7	ascertained	ascertain	VBN
cord-353633-a4pu6rlu	150	8	as	as	IN
cord-353633-a4pu6rlu	150	9	the	the	DT
cord-353633-a4pu6rlu	150	10	most	most	RBS
cord-353633-a4pu6rlu	150	11	significantly	significantly	RB
cord-353633-a4pu6rlu	150	12	upregulated	upregulate	VBN
cord-353633-a4pu6rlu	150	13	transcript	transcript	NN
cord-353633-a4pu6rlu	150	14	in	in	IN
cord-353633-a4pu6rlu	150	15	advanced	advanced	JJ
cord-353633-a4pu6rlu	150	16	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	150	17	and	and	CC
cord-353633-a4pu6rlu	150	18	NASH	NASH	NNP
cord-353633-a4pu6rlu	150	19	(	(	-LRB-
cord-353633-a4pu6rlu	150	20	fold	fold	JJ
cord-353633-a4pu6rlu	150	21	-	-	HYPH
cord-353633-a4pu6rlu	150	22	change	change	NN
cord-353633-a4pu6rlu	150	23	=	=	SYM
cord-353633-a4pu6rlu	150	24	2.3	2.3	CD
cord-353633-a4pu6rlu	150	25	vs	vs	IN
cord-353633-a4pu6rlu	150	26	non	non	NNP
cord-353633-a4pu6rlu	150	27	-	-	JJ
cord-353633-a4pu6rlu	150	28	NASH	NASH	NNP
cord-353633-a4pu6rlu	150	29	)	)	-RRB-
cord-353633-a4pu6rlu	150	30	,	,	,
cord-353633-a4pu6rlu	150	31	correlating	correlate	VBG
cord-353633-a4pu6rlu	150	32	with	with	IN
cord-353633-a4pu6rlu	150	33	lipid	lipid	NN
cord-353633-a4pu6rlu	150	34	accumulation	accumulation	NN
cord-353633-a4pu6rlu	150	35	and	and	CC
cord-353633-a4pu6rlu	150	36	disease	disease	NN
cord-353633-a4pu6rlu	150	37	severity	severity	NN
cord-353633-a4pu6rlu	150	38	[	[	-LRB-
cord-353633-a4pu6rlu	150	39	88	88	CD
cord-353633-a4pu6rlu	150	40	]	]	-RRB-
cord-353633-a4pu6rlu	150	41	.	.	.
cord-353633-a4pu6rlu	151	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	151	2	,	,	,
cord-353633-a4pu6rlu	151	3	several	several	JJ
cord-353633-a4pu6rlu	151	4	cancerrelated	cancerrelated	JJ
cord-353633-a4pu6rlu	151	5	genes	gene	NNS
cord-353633-a4pu6rlu	151	6	,	,	,
cord-353633-a4pu6rlu	151	7	such	such	JJ
cord-353633-a4pu6rlu	151	8	as	as	IN
cord-353633-a4pu6rlu	151	9	AKR1B10	AKR1B10	NNP
cord-353633-a4pu6rlu	151	10	,	,	,
cord-353633-a4pu6rlu	151	11	KRT23	KRT23	NNP
cord-353633-a4pu6rlu	151	12	and	and	CC
cord-353633-a4pu6rlu	151	13	GPC3	GPC3	NNP
cord-353633-a4pu6rlu	151	14	,	,	,
cord-353633-a4pu6rlu	151	15	are	be	VBP
cord-353633-a4pu6rlu	151	16	enhanced	enhance	VBN
cord-353633-a4pu6rlu	151	17	in	in	IN
cord-353633-a4pu6rlu	151	18	NASH	NASH	NNP
cord-353633-a4pu6rlu	151	19	compared	compare	VBN
cord-353633-a4pu6rlu	151	20	with	with	IN
cord-353633-a4pu6rlu	151	21	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	151	22	or	or	CC
cord-353633-a4pu6rlu	151	23	controls	control	NNS
cord-353633-a4pu6rlu	151	24	,	,	,
cord-353633-a4pu6rlu	151	25	by	by	IN
cord-353633-a4pu6rlu	151	26	up	up	IN
cord-353633-a4pu6rlu	151	27	to	to	TO
cord-353633-a4pu6rlu	151	28	155-fold	155-fold	CD
cord-353633-a4pu6rlu	151	29	and	and	CC
cord-353633-a4pu6rlu	151	30	460-fold	460-fold	CD
cord-353633-a4pu6rlu	151	31	respectively	respectively	RB
cord-353633-a4pu6rlu	151	32	[	[	-LRB-
cord-353633-a4pu6rlu	151	33	96	96	CD
cord-353633-a4pu6rlu	151	34	]	]	-RRB-
cord-353633-a4pu6rlu	151	35	.	.	.
cord-353633-a4pu6rlu	152	1	Concerning	concern	VBG
cord-353633-a4pu6rlu	152	2	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	152	3	,	,	,
cord-353633-a4pu6rlu	152	4	cross	cross	JJ
cord-353633-a4pu6rlu	152	5	-	-	JJ
cord-353633-a4pu6rlu	152	6	sectional	sectional	JJ
cord-353633-a4pu6rlu	152	7	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	152	8	analysis	analysis	NN
cord-353633-a4pu6rlu	152	9	of	of	IN
cord-353633-a4pu6rlu	152	10	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	152	11	cells	cell	NNS
cord-353633-a4pu6rlu	152	12	defines	define	VBZ
cord-353633-a4pu6rlu	152	13	3820	3820	CD
cord-353633-a4pu6rlu	152	14	and	and	CC
cord-353633-a4pu6rlu	152	15	2980	2980	CD
cord-353633-a4pu6rlu	152	16	differentially	differentially	RB
cord-353633-a4pu6rlu	152	17	expressed	express	VBN
cord-353633-a4pu6rlu	152	18	transcripts	transcript	NNS
cord-353633-a4pu6rlu	152	19	for	for	IN
cord-353633-a4pu6rlu	152	20	the	the	DT
cord-353633-a4pu6rlu	152	21	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	152	22	and	and	CC
cord-353633-a4pu6rlu	152	23	fibrotic	fibrotic	JJ
cord-353633-a4pu6rlu	152	24	states	state	NNS
cord-353633-a4pu6rlu	152	25	,	,	,
cord-353633-a4pu6rlu	152	26	respectively	respectively	RB
cord-353633-a4pu6rlu	152	27	,	,	,
cord-353633-a4pu6rlu	152	28	and	and	CC
cord-353633-a4pu6rlu	152	29	further	further	RB
cord-353633-a4pu6rlu	152	30	underlines	underline	VBZ
cord-353633-a4pu6rlu	152	31	16	16	CD
cord-353633-a4pu6rlu	152	32	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	152	33	-	-	HYPH
cord-353633-a4pu6rlu	152	34	defining	define	VBG
cord-353633-a4pu6rlu	152	35	genetic	genetic	JJ
cord-353633-a4pu6rlu	152	36	routes	route	NNS
cord-353633-a4pu6rlu	152	37	,	,	,
cord-353633-a4pu6rlu	152	38	pertaining	pertain	VBG
cord-353633-a4pu6rlu	152	39	to	to	IN
cord-353633-a4pu6rlu	152	40	cytokine	cytokine	NN
cord-353633-a4pu6rlu	152	41	and	and	CC
cord-353633-a4pu6rlu	152	42	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	152	43	matrix	matrix	NN
cord-353633-a4pu6rlu	152	44	receptor	receptor	NN
cord-353633-a4pu6rlu	152	45	interaction	interaction	NN
cord-353633-a4pu6rlu	152	46	,	,	,
cord-353633-a4pu6rlu	152	47	focal	focal	JJ
cord-353633-a4pu6rlu	152	48	adhesion	adhesion	NN
cord-353633-a4pu6rlu	152	49	and	and	CC
cord-353633-a4pu6rlu	152	50	the	the	DT
cord-353633-a4pu6rlu	152	51	PI3K	PI3K	NNP
cord-353633-a4pu6rlu	152	52	-	-	HYPH
cord-353633-a4pu6rlu	152	53	Akt	Akt	NNP
cord-353633-a4pu6rlu	152	54	signaling	signal	VBG
cord-353633-a4pu6rlu	152	55	pathway	pathway	NN
cord-353633-a4pu6rlu	152	56	[	[	-LRB-
cord-353633-a4pu6rlu	152	57	98	98	CD
cord-353633-a4pu6rlu	152	58	]	]	-RRB-
cord-353633-a4pu6rlu	152	59	.	.	.
cord-353633-a4pu6rlu	153	1	Differentially	differentially	RB
cord-353633-a4pu6rlu	153	2	expressed	express	VBN
cord-353633-a4pu6rlu	153	3	microarray	microarray	NN
cord-353633-a4pu6rlu	153	4	signals	signal	NNS
cord-353633-a4pu6rlu	153	5	,	,	,
cord-353633-a4pu6rlu	153	6	such	such	JJ
cord-353633-a4pu6rlu	153	7	as	as	IN
cord-353633-a4pu6rlu	153	8	UBE2V1	UBE2V1	NNP
cord-353633-a4pu6rlu	153	9	,	,	,
cord-353633-a4pu6rlu	153	10	BNIP3L	bnip3l	NN
cord-353633-a4pu6rlu	153	11	,	,	,
cord-353633-a4pu6rlu	153	12	RP11	RP11	NNP
cord-353633-a4pu6rlu	153	13	-	-	HYPH
cord-353633-a4pu6rlu	153	14	128N14.5	128N14.5	NNP
cord-353633-a4pu6rlu	153	15	,	,	,
cord-353633-a4pu6rlu	153	16	linked	link	VBN
cord-353633-a4pu6rlu	153	17	to	to	IN
cord-353633-a4pu6rlu	153	18	oxidative	oxidative	JJ
cord-353633-a4pu6rlu	153	19	stress	stress	NN
cord-353633-a4pu6rlu	153	20	,	,	,
cord-353633-a4pu6rlu	153	21	inflammation	inflammation	NN
cord-353633-a4pu6rlu	153	22	,	,	,
cord-353633-a4pu6rlu	153	23	apoptosis	apoptosis	NN
cord-353633-a4pu6rlu	153	24	and	and	CC
cord-353633-a4pu6rlu	153	25	fibrogenesis	fibrogenesis	NN
cord-353633-a4pu6rlu	153	26	,	,	,
cord-353633-a4pu6rlu	153	27	are	be	VBP
cord-353633-a4pu6rlu	153	28	upregulated	upregulate	VBN
cord-353633-a4pu6rlu	153	29	in	in	IN
cord-353633-a4pu6rlu	153	30	NAS	NAS	NNP
cord-353633-a4pu6rlu	153	31	≥	≥	CD
cord-353633-a4pu6rlu	153	32	5	5	CD
cord-353633-a4pu6rlu	153	33	and	and	CC
cord-353633-a4pu6rlu	153	34	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	153	35	stages	stage	NNS
cord-353633-a4pu6rlu	154	1	3	3	LS
cord-353633-a4pu6rlu	154	2	-	-	SYM
cord-353633-a4pu6rlu	154	3	4	4	CD
cord-353633-a4pu6rlu	154	4	[	[	-LRB-
cord-353633-a4pu6rlu	154	5	99	99	CD
cord-353633-a4pu6rlu	154	6	]	]	-RRB-
cord-353633-a4pu6rlu	154	7	.	.	.
cord-353633-a4pu6rlu	155	1	J	J	NNP
cord-353633-a4pu6rlu	155	2	o	o	NN
cord-353633-a4pu6rlu	155	3	u	u	NN
cord-353633-a4pu6rlu	155	4	r	r	NN
cord-353633-a4pu6rlu	155	5	n	n	NN
cord-353633-a4pu6rlu	155	6	a	a	DT
cord-353633-a4pu6rlu	155	7	l	l	NN
cord-353633-a4pu6rlu	155	8	P	p	NN
cord-353633-a4pu6rlu	155	9	r	r	NN
cord-353633-a4pu6rlu	155	10	e	e	NN
cord-353633-a4pu6rlu	155	11	-p	-p	NN
cord-353633-a4pu6rlu	156	1	r	r	LS
cord-353633-a4pu6rlu	157	1	o	o	UH
cord-353633-a4pu6rlu	158	1	o	o	UH
cord-353633-a4pu6rlu	158	2	f	f	NNP
cord-353633-a4pu6rlu	158	3	Likewise	likewise	RB
cord-353633-a4pu6rlu	158	4	,	,	,
cord-353633-a4pu6rlu	158	5	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	158	6	pinpoint	pinpoint	VBP
cord-353633-a4pu6rlu	158	7	dermatopontin	dermatopontin	NNP
cord-353633-a4pu6rlu	158	8	,	,	,
cord-353633-a4pu6rlu	158	9	a	a	DT
cord-353633-a4pu6rlu	158	10	propagator	propagator	NN
cord-353633-a4pu6rlu	158	11	of	of	IN
cord-353633-a4pu6rlu	158	12	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	158	13	matrix	matrix	NN
cord-353633-a4pu6rlu	158	14	remodeling	remodeling	NN
cord-353633-a4pu6rlu	158	15	,	,	,
cord-353633-a4pu6rlu	158	16	which	which	WDT
cord-353633-a4pu6rlu	158	17	is	be	VBZ
cord-353633-a4pu6rlu	158	18	robustly	robustly	RB
cord-353633-a4pu6rlu	158	19	expressed	express	VBN
cord-353633-a4pu6rlu	158	20	(	(	-LRB-
cord-353633-a4pu6rlu	158	21	by	by	IN
cord-353633-a4pu6rlu	158	22	800-fold	800-fold	CD
cord-353633-a4pu6rlu	158	23	)	)	-RRB-
cord-353633-a4pu6rlu	158	24	in	in	IN
cord-353633-a4pu6rlu	158	25	murine	murine	JJ
cord-353633-a4pu6rlu	158	26	stellate	stellate	JJ
cord-353633-a4pu6rlu	158	27	cells	cell	NNS
cord-353633-a4pu6rlu	158	28	,	,	,
cord-353633-a4pu6rlu	158	29	enhanced	enhance	VBN
cord-353633-a4pu6rlu	158	30	in	in	IN
cord-353633-a4pu6rlu	158	31	human	human	JJ
cord-353633-a4pu6rlu	158	32	fibrotic	fibrotic	JJ
cord-353633-a4pu6rlu	158	33	livers	liver	NNS
cord-353633-a4pu6rlu	158	34	and	and	CC
cord-353633-a4pu6rlu	158	35	implicated	implicate	VBN
cord-353633-a4pu6rlu	158	36	in	in	IN
cord-353633-a4pu6rlu	158	37	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	158	38	fibrogenesis	fibrogenesis	NN
cord-353633-a4pu6rlu	158	39	[	[	-LRB-
cord-353633-a4pu6rlu	158	40	100	100	CD
cord-353633-a4pu6rlu	158	41	]	]	-RRB-
cord-353633-a4pu6rlu	158	42	.	.	.
cord-353633-a4pu6rlu	159	1	Minor	minor	JJ
cord-353633-a4pu6rlu	159	2	molecules	molecule	NNS
cord-353633-a4pu6rlu	159	3	such	such	JJ
cord-353633-a4pu6rlu	159	4	as	as	IN
cord-353633-a4pu6rlu	159	5	micro	micro	NNS
cord-353633-a4pu6rlu	159	6	-	-	NNS
cord-353633-a4pu6rlu	159	7	RNAs	RNAs	NNPS
cord-353633-a4pu6rlu	159	8	(	(	-LRB-
cord-353633-a4pu6rlu	159	9	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	159	10	)	)	-RRB-
cord-353633-a4pu6rlu	159	11	along	along	IN
cord-353633-a4pu6rlu	159	12	with	with	IN
cord-353633-a4pu6rlu	159	13	long	long	JJ
cord-353633-a4pu6rlu	159	14	noncoding	noncoding	JJ
cord-353633-a4pu6rlu	159	15	RNAs	rna	NNS
cord-353633-a4pu6rlu	159	16	(	(	-LRB-
cord-353633-a4pu6rlu	159	17	lncRNA	lncRNA	NNP
cord-353633-a4pu6rlu	159	18	)	)	-RRB-
cord-353633-a4pu6rlu	159	19	perform	perform	VB
cord-353633-a4pu6rlu	159	20	a	a	DT
cord-353633-a4pu6rlu	159	21	variety	variety	NN
cord-353633-a4pu6rlu	159	22	of	of	IN
cord-353633-a4pu6rlu	159	23	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	159	24	and	and	CC
cord-353633-a4pu6rlu	159	25	post	post	JJ
cord-353633-a4pu6rlu	159	26	-	-	JJ
cord-353633-a4pu6rlu	159	27	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	159	28	functions	function	NNS
cord-353633-a4pu6rlu	159	29	,	,	,
cord-353633-a4pu6rlu	159	30	thus	thus	RB
cord-353633-a4pu6rlu	159	31	significantly	significantly	RB
cord-353633-a4pu6rlu	159	32	affecting	affect	VBG
cord-353633-a4pu6rlu	159	33	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	159	34	activity	activity	NN
cord-353633-a4pu6rlu	159	35	in	in	IN
cord-353633-a4pu6rlu	159	36	numerous	numerous	JJ
cord-353633-a4pu6rlu	159	37	diseases	disease	NNS
cord-353633-a4pu6rlu	159	38	and	and	CC
cord-353633-a4pu6rlu	159	39	among	among	IN
cord-353633-a4pu6rlu	159	40	them	-PRON-	PRP
cord-353633-a4pu6rlu	159	41	also	also	RB
cord-353633-a4pu6rlu	159	42	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	159	43	[	[	-LRB-
cord-353633-a4pu6rlu	159	44	101	101	CD
cord-353633-a4pu6rlu	159	45	]	]	-RRB-
cord-353633-a4pu6rlu	159	46	.	.	.
cord-353633-a4pu6rlu	160	1	For	for	IN
cord-353633-a4pu6rlu	160	2	this	this	DT
cord-353633-a4pu6rlu	160	3	reason	reason	NN
cord-353633-a4pu6rlu	160	4	,	,	,
cord-353633-a4pu6rlu	160	5	they	-PRON-	PRP
cord-353633-a4pu6rlu	160	6	are	be	VBP
cord-353633-a4pu6rlu	160	7	also	also	RB
cord-353633-a4pu6rlu	160	8	considered	consider	VBN
cord-353633-a4pu6rlu	160	9	important	important	JJ
cord-353633-a4pu6rlu	160	10	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	160	11	modifiers	modifier	NNS
cord-353633-a4pu6rlu	160	12	.	.	.
cord-353633-a4pu6rlu	161	1	These	these	DT
cord-353633-a4pu6rlu	161	2	processes	process	NNS
cord-353633-a4pu6rlu	161	3	are	be	VBP
cord-353633-a4pu6rlu	161	4	thoroughly	thoroughly	RB
cord-353633-a4pu6rlu	161	5	delineated	delineate	VBN
cord-353633-a4pu6rlu	161	6	through	through	IN
cord-353633-a4pu6rlu	161	7	large	large	JJ
cord-353633-a4pu6rlu	161	8	panels	panel	NNS
cord-353633-a4pu6rlu	161	9	of	of	IN
cord-353633-a4pu6rlu	161	10	differential	differential	JJ
cord-353633-a4pu6rlu	161	11	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	161	12	expression	expression	NN
cord-353633-a4pu6rlu	161	13	[	[	-LRB-
cord-353633-a4pu6rlu	161	14	102	102	CD
cord-353633-a4pu6rlu	161	15	]	]	-RRB-
cord-353633-a4pu6rlu	161	16	[	[	-LRB-
cord-353633-a4pu6rlu	161	17	103	103	CD
cord-353633-a4pu6rlu	161	18	]	]	-RRB-
cord-353633-a4pu6rlu	161	19	[	[	-LRB-
cord-353633-a4pu6rlu	161	20	104	104	CD
cord-353633-a4pu6rlu	161	21	]	]	-RRB-
cord-353633-a4pu6rlu	162	1	while	while	IN
cord-353633-a4pu6rlu	162	2	the	the	DT
cord-353633-a4pu6rlu	162	3	distinct	distinct	JJ
cord-353633-a4pu6rlu	162	4	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	162	5	-	-	HYPH
cord-353633-a4pu6rlu	162	6	related	relate	VBN
cord-353633-a4pu6rlu	162	7	roles	role	NNS
cord-353633-a4pu6rlu	162	8	of	of	IN
cord-353633-a4pu6rlu	162	9	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	162	10	subspecies	subspecie	NNS
cord-353633-a4pu6rlu	162	11	were	be	VBD
cord-353633-a4pu6rlu	162	12	recently	recently	RB
cord-353633-a4pu6rlu	162	13	reviewed	review	VBN
cord-353633-a4pu6rlu	162	14	[	[	-LRB-
cord-353633-a4pu6rlu	162	15	101	101	CD
cord-353633-a4pu6rlu	162	16	,	,	,
cord-353633-a4pu6rlu	162	17	105	105	CD
cord-353633-a4pu6rlu	162	18	]	]	-RRB-
cord-353633-a4pu6rlu	162	19	.	.	.
cord-353633-a4pu6rlu	163	1	Of	of	IN
cord-353633-a4pu6rlu	163	2	note	note	NN
cord-353633-a4pu6rlu	163	3	,	,	,
cord-353633-a4pu6rlu	163	4	microRNA-122	microrna-122	FW
cord-353633-a4pu6rlu	163	5	(	(	-LRB-
cord-353633-a4pu6rlu	163	6	miR-122	miR-122	NNP
cord-353633-a4pu6rlu	163	7	)	)	-RRB-
cord-353633-a4pu6rlu	163	8	,	,	,
cord-353633-a4pu6rlu	163	9	deriving	derive	VBG
cord-353633-a4pu6rlu	163	10	from	from	IN
cord-353633-a4pu6rlu	163	11	chromosome	chromosome	NN
cord-353633-a4pu6rlu	163	12	18	18	CD
cord-353633-a4pu6rlu	163	13	,	,	,
cord-353633-a4pu6rlu	163	14	represents	represent	VBZ
cord-353633-a4pu6rlu	163	15	70	70	CD
cord-353633-a4pu6rlu	163	16	%	%	NN
cord-353633-a4pu6rlu	163	17	of	of	IN
cord-353633-a4pu6rlu	163	18	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	163	19	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	163	20	and	and	CC
cord-353633-a4pu6rlu	163	21	has	have	VBZ
cord-353633-a4pu6rlu	163	22	been	be	VBN
cord-353633-a4pu6rlu	163	23	implicated	implicate	VBN
cord-353633-a4pu6rlu	163	24	in	in	IN
cord-353633-a4pu6rlu	163	25	cholesterol	cholesterol	NN
cord-353633-a4pu6rlu	163	26	metabolism	metabolism	NN
cord-353633-a4pu6rlu	163	27	and	and	CC
cord-353633-a4pu6rlu	163	28	liver	liver	NN
cord-353633-a4pu6rlu	163	29	cancer	cancer	NN
cord-353633-a4pu6rlu	163	30	[	[	-LRB-
cord-353633-a4pu6rlu	163	31	106	106	CD
cord-353633-a4pu6rlu	163	32	]	]	-RRB-
cord-353633-a4pu6rlu	163	33	.	.	.
cord-353633-a4pu6rlu	164	1	Cheung	Cheung	NNP
cord-353633-a4pu6rlu	164	2	et	et	NNP
cord-353633-a4pu6rlu	164	3	al	al	NNP
cord-353633-a4pu6rlu	164	4	.	.	.
cord-353633-a4pu6rlu	165	1	first	first	RB
cord-353633-a4pu6rlu	165	2	mapped	map	VBD
cord-353633-a4pu6rlu	165	3	a	a	DT
cord-353633-a4pu6rlu	165	4	63	63	CD
cord-353633-a4pu6rlu	165	5	%	%	NN
cord-353633-a4pu6rlu	165	6	underexpression	underexpression	NN
cord-353633-a4pu6rlu	165	7	of	of	IN
cord-353633-a4pu6rlu	165	8	liver	liver	NNP
cord-353633-a4pu6rlu	165	9	miR-122	miR-122	NNP
cord-353633-a4pu6rlu	165	10	in	in	IN
cord-353633-a4pu6rlu	165	11	NASH	NASH	NNP
cord-353633-a4pu6rlu	165	12	patients	patient	NNS
cord-353633-a4pu6rlu	165	13	compared	compare	VBN
cord-353633-a4pu6rlu	165	14	with	with	IN
cord-353633-a4pu6rlu	165	15	controls	control	NNS
cord-353633-a4pu6rlu	165	16	,	,	,
cord-353633-a4pu6rlu	165	17	through	through	IN
cord-353633-a4pu6rlu	165	18	an	an	DT
cord-353633-a4pu6rlu	165	19	evaluation	evaluation	NN
cord-353633-a4pu6rlu	165	20	of	of	IN
cord-353633-a4pu6rlu	165	21	a	a	DT
cord-353633-a4pu6rlu	165	22	474-miRNA	474-mirna	CD
cord-353633-a4pu6rlu	165	23	panel	panel	NN
cord-353633-a4pu6rlu	165	24	that	that	WDT
cord-353633-a4pu6rlu	165	25	identified	identify	VBD
cord-353633-a4pu6rlu	165	26	46	46	CD
cord-353633-a4pu6rlu	165	27	differentially	differentially	RB
cord-353633-a4pu6rlu	165	28	expressed	express	VBN
cord-353633-a4pu6rlu	165	29	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	165	30	species	specie	NNS
cord-353633-a4pu6rlu	165	31	and	and	CC
cord-353633-a4pu6rlu	165	32	their	-PRON-	PRP$
cord-353633-a4pu6rlu	165	33	corresponding	correspond	VBG
cord-353633-a4pu6rlu	165	34	targets	target	NNS
cord-353633-a4pu6rlu	165	35	[	[	-LRB-
cord-353633-a4pu6rlu	165	36	104	104	CD
cord-353633-a4pu6rlu	165	37	]	]	-RRB-
cord-353633-a4pu6rlu	165	38	.	.	.
cord-353633-a4pu6rlu	166	1	MiR-122	MiR-122	NNP
cord-353633-a4pu6rlu	166	2	was	be	VBD
cord-353633-a4pu6rlu	166	3	subsequently	subsequently	RB
cord-353633-a4pu6rlu	166	4	associated	associate	VBN
cord-353633-a4pu6rlu	166	5	with	with	IN
cord-353633-a4pu6rlu	166	6	steatosis	steatosis	NN
cord-353633-a4pu6rlu	166	7	severity	severity	NN
cord-353633-a4pu6rlu	166	8	[	[	-LRB-
cord-353633-a4pu6rlu	166	9	107	107	CD
cord-353633-a4pu6rlu	166	10	]	]	-RRB-
cord-353633-a4pu6rlu	166	11	.	.	.
cord-353633-a4pu6rlu	167	1	The	the	DT
cord-353633-a4pu6rlu	167	2	(	(	-LRB-
cord-353633-a4pu6rlu	167	3	a	a	NN
cord-353633-a4pu6rlu	167	4	,	,	,
cord-353633-a4pu6rlu	167	5	b	b	NNP
cord-353633-a4pu6rlu	167	6	)	)	-RRB-
cord-353633-a4pu6rlu	167	7	,	,	,
cord-353633-a4pu6rlu	167	8	miR-125b	mir-125b	CD
cord-353633-a4pu6rlu	167	9	(	(	-LRB-
cord-353633-a4pu6rlu	167	10	associated	associate	VBN
cord-353633-a4pu6rlu	167	11	with	with	IN
cord-353633-a4pu6rlu	167	12	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	167	13	syndrome	syndrome	NN
cord-353633-a4pu6rlu	167	14	,	,	,
cord-353633-a4pu6rlu	167	15	atherogenesis	atherogenesis	NN
cord-353633-a4pu6rlu	167	16	and	and	CC
cord-353633-a4pu6rlu	167	17	circulation	circulation	NN
cord-353633-a4pu6rlu	167	18	)	)	-RRB-
cord-353633-a4pu6rlu	167	19	[	[	-LRB-
cord-353633-a4pu6rlu	167	20	103	103	CD
cord-353633-a4pu6rlu	167	21	]	]	-RRB-
cord-353633-a4pu6rlu	167	22	as	as	RB
cord-353633-a4pu6rlu	167	23	well	well	RB
cord-353633-a4pu6rlu	167	24	as	as	IN
cord-353633-a4pu6rlu	167	25	miR-34a	miR-34a	NNP
cord-353633-a4pu6rlu	167	26	,	,	,
cord-353633-a4pu6rlu	167	27	miR-16	mir-16	JJ
cord-353633-a4pu6rlu	167	28	(	(	-LRB-
cord-353633-a4pu6rlu	167	29	associated	associate	VBN
cord-353633-a4pu6rlu	167	30	with	with	IN
cord-353633-a4pu6rlu	167	31	cancer	cancer	NN
cord-353633-a4pu6rlu	167	32	)	)	-RRB-
cord-353633-a4pu6rlu	167	33	[	[	-LRB-
cord-353633-a4pu6rlu	167	34	108	108	CD
cord-353633-a4pu6rlu	167	35	]	]	-RRB-
cord-353633-a4pu6rlu	167	36	,	,	,
cord-353633-a4pu6rlu	167	37	miR-21	miR-21	NNP
cord-353633-a4pu6rlu	167	38	and	and	CC
cord-353633-a4pu6rlu	167	39	miR-451	miR-451	NNP
cord-353633-a4pu6rlu	167	40	[	[	-LRB-
cord-353633-a4pu6rlu	167	41	107	107	CD
cord-353633-a4pu6rlu	167	42	]	]	-RRB-
cord-353633-a4pu6rlu	167	43	are	be	VBP
cord-353633-a4pu6rlu	167	44	upregulated	upregulate	VBN
cord-353633-a4pu6rlu	167	45	in	in	IN
cord-353633-a4pu6rlu	167	46	both	both	CC
cord-353633-a4pu6rlu	167	47	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	167	48	and	and	CC
cord-353633-a4pu6rlu	167	49	NASH	NASH	NNP
cord-353633-a4pu6rlu	167	50	.	.	.
cord-353633-a4pu6rlu	168	1	Moreover	moreover	RB
cord-353633-a4pu6rlu	168	2	,	,	,
cord-353633-a4pu6rlu	168	3	miR-301a	miR-301a	NNS
cord-353633-a4pu6rlu	168	4	,	,	,
cord-353633-a4pu6rlu	168	5	miR-34a	miR-34a	NNP
cord-353633-a4pu6rlu	168	6	and	and	CC
cord-353633-a4pu6rlu	168	7	miR-375	miR-375	NNP
cord-353633-a4pu6rlu	168	8	alter	alter	VBP
cord-353633-a4pu6rlu	168	9	lipid	lipid	NN
cord-353633-a4pu6rlu	168	10	and	and	CC
cord-353633-a4pu6rlu	168	11	carbohydrate	carbohydrate	NN
cord-353633-a4pu6rlu	169	1	J	J	NNP
cord-353633-a4pu6rlu	169	2	o	o	NN
cord-353633-a4pu6rlu	169	3	u	u	NN
cord-353633-a4pu6rlu	169	4	r	r	NN
cord-353633-a4pu6rlu	169	5	n	n	NN
cord-353633-a4pu6rlu	169	6	a	a	DT
cord-353633-a4pu6rlu	169	7	l	l	NN
cord-353633-a4pu6rlu	169	8	P	p	NN
cord-353633-a4pu6rlu	169	9	r	r	NN
cord-353633-a4pu6rlu	169	10	e	e	NN
cord-353633-a4pu6rlu	169	11	-p	-p	NN
cord-353633-a4pu6rlu	169	12	r	r	NN
cord-353633-a4pu6rlu	169	13	o	o	NN
cord-353633-a4pu6rlu	169	14	o	o	NN
cord-353633-a4pu6rlu	169	15	f	f	NN
cord-353633-a4pu6rlu	169	16	26	26	CD
cord-353633-a4pu6rlu	169	17	metabolism	metabolism	NN
cord-353633-a4pu6rlu	169	18	,	,	,
cord-353633-a4pu6rlu	169	19	reflect	reflect	VBP
cord-353633-a4pu6rlu	169	20	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	169	21	severity	severity	NN
cord-353633-a4pu6rlu	169	22	and	and	CC
cord-353633-a4pu6rlu	169	23	are	be	VBP
cord-353633-a4pu6rlu	169	24	implicated	implicate	VBN
cord-353633-a4pu6rlu	169	25	in	in	IN
cord-353633-a4pu6rlu	169	26	hepatocellular	hepatocellular	JJ
cord-353633-a4pu6rlu	169	27	carcinomas	carcinoma	NNS
cord-353633-a4pu6rlu	169	28	[	[	-LRB-
cord-353633-a4pu6rlu	169	29	102	102	CD
cord-353633-a4pu6rlu	169	30	]	]	-RRB-
cord-353633-a4pu6rlu	169	31	.	.	.
cord-353633-a4pu6rlu	170	1	Expression	expression	NN
cord-353633-a4pu6rlu	170	2	levels	level	NNS
cord-353633-a4pu6rlu	170	3	of	of	IN
cord-353633-a4pu6rlu	170	4	lesser	less	JJR
cord-353633-a4pu6rlu	170	5	non	non	JJ
cord-353633-a4pu6rlu	170	6	-	-	JJ
cord-353633-a4pu6rlu	170	7	coding	coding	JJ
cord-353633-a4pu6rlu	170	8	molecules	molecule	NNS
cord-353633-a4pu6rlu	170	9	have	have	VBP
cord-353633-a4pu6rlu	170	10	also	also	RB
cord-353633-a4pu6rlu	170	11	been	be	VBN
cord-353633-a4pu6rlu	170	12	investigated	investigate	VBN
cord-353633-a4pu6rlu	170	13	[	[	-LRB-
cord-353633-a4pu6rlu	170	14	99	99	CD
cord-353633-a4pu6rlu	170	15	,	,	,
cord-353633-a4pu6rlu	170	16	109	109	CD
cord-353633-a4pu6rlu	170	17	,	,	,
cord-353633-a4pu6rlu	170	18	110	110	CD
cord-353633-a4pu6rlu	170	19	]	]	-RRB-
cord-353633-a4pu6rlu	170	20	.	.	.
cord-353633-a4pu6rlu	171	1	Global	global	JJ
cord-353633-a4pu6rlu	171	2	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	171	3	RNA	RNA	NNP
cord-353633-a4pu6rlu	171	4	profiling	profiling	NN
cord-353633-a4pu6rlu	171	5	has	have	VBZ
cord-353633-a4pu6rlu	171	6	identified	identify	VBN
cord-353633-a4pu6rlu	171	7	535	535	CD
cord-353633-a4pu6rlu	171	8	lncRNA	lncRNA	NNS
cord-353633-a4pu6rlu	171	9	and	and	CC
cord-353633-a4pu6rlu	171	10	760	760	CD
cord-353633-a4pu6rlu	171	11	mRNA	mrna	NN
cord-353633-a4pu6rlu	171	12	species	specie	NNS
cord-353633-a4pu6rlu	171	13	overexpressed	overexpresse	VBN
cord-353633-a4pu6rlu	171	14	in	in	IN
cord-353633-a4pu6rlu	171	15	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	171	16	,	,	,
cord-353633-a4pu6rlu	171	17	whereas	whereas	IN
cord-353633-a4pu6rlu	171	18	1200	1200	CD
cord-353633-a4pu6rlu	171	19	lncRNA	lncRNA	NNS
cord-353633-a4pu6rlu	171	20	and	and	CC
cord-353633-a4pu6rlu	171	21	725	725	CD
cord-353633-a4pu6rlu	171	22	mRNA	mrna	NN
cord-353633-a4pu6rlu	171	23	species	specie	NNS
cord-353633-a4pu6rlu	171	24	are	be	VBP
cord-353633-a4pu6rlu	171	25	underexpressed	underexpresse	VBN
cord-353633-a4pu6rlu	171	26	.	.	.
cord-353633-a4pu6rlu	172	1	These	these	DT
cord-353633-a4pu6rlu	172	2	enriched	enrich	VBN
cord-353633-a4pu6rlu	172	3	RNAs	rna	NNS
cord-353633-a4pu6rlu	172	4	chiefly	chiefly	RB
cord-353633-a4pu6rlu	172	5	belong	belong	VBP
cord-353633-a4pu6rlu	172	6	to	to	IN
cord-353633-a4pu6rlu	172	7	small	small	JJ
cord-353633-a4pu6rlu	172	8	molecule	molecule	NN
cord-353633-a4pu6rlu	172	9	and	and	CC
cord-353633-a4pu6rlu	172	10	organic	organic	JJ
cord-353633-a4pu6rlu	172	11	acid	acid	NN
cord-353633-a4pu6rlu	172	12	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	172	13	pathways	pathway	NNS
cord-353633-a4pu6rlu	172	14	[	[	-LRB-
cord-353633-a4pu6rlu	172	15	109	109	CD
cord-353633-a4pu6rlu	172	16	]	]	-RRB-
cord-353633-a4pu6rlu	172	17	.	.	.
cord-353633-a4pu6rlu	173	1	Functional	functional	JJ
cord-353633-a4pu6rlu	173	2	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	173	3	research	research	NN
cord-353633-a4pu6rlu	173	4	of	of	IN
cord-353633-a4pu6rlu	173	5	4383	4383	CD
cord-353633-a4pu6rlu	173	6	lncRNA	lncrna	NN
cord-353633-a4pu6rlu	173	7	species	specie	NNS
cord-353633-a4pu6rlu	173	8	by	by	IN
cord-353633-a4pu6rlu	173	9	Atanasovka	Atanasovka	NNP
cord-353633-a4pu6rlu	173	10	et	et	NNP
cord-353633-a4pu6rlu	173	11	al	al	NNP
cord-353633-a4pu6rlu	173	12	.	.	.
cord-353633-a4pu6rlu	174	1	pinpoints	pinpoint	VBZ
cord-353633-a4pu6rlu	174	2	elevated	elevated	JJ
cord-353633-a4pu6rlu	174	3	levels	level	NNS
cord-353633-a4pu6rlu	174	4	of	of	IN
cord-353633-a4pu6rlu	174	5	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	174	6	lncRNA	lncrna	NN
cord-353633-a4pu6rlu	174	7	RP11	RP11	NNP
cord-353633-a4pu6rlu	174	8	-	-	HYPH
cord-353633-a4pu6rlu	174	9	484N16.1	484N16.1	NNP
cord-353633-a4pu6rlu	174	10	in	in	IN
cord-353633-a4pu6rlu	174	11	NASH	NASH	NNP
cord-353633-a4pu6rlu	174	12	,	,	,
cord-353633-a4pu6rlu	174	13	and	and	CC
cord-353633-a4pu6rlu	174	14	robustly	robustly	RB
cord-353633-a4pu6rlu	174	15	associates	associate	VBZ
cord-353633-a4pu6rlu	174	16	it	-PRON-	PRP
cord-353633-a4pu6rlu	174	17	with	with	IN
cord-353633-a4pu6rlu	174	18	NASH	NASH	NNP
cord-353633-a4pu6rlu	174	19	grade	grade	NN
cord-353633-a4pu6rlu	174	20	,	,	,
cord-353633-a4pu6rlu	174	21	lobular	lobular	JJ
cord-353633-a4pu6rlu	174	22	inflammation	inflammation	NN
cord-353633-a4pu6rlu	174	23	and	and	CC
cord-353633-a4pu6rlu	174	24	NAS	NAS	NNP
cord-353633-a4pu6rlu	174	25	,	,	,
cord-353633-a4pu6rlu	174	26	while	while	IN
cord-353633-a4pu6rlu	174	27	its	-PRON-	PRP$
cord-353633-a4pu6rlu	174	28	knockdown	knockdown	NN
cord-353633-a4pu6rlu	174	29	in	in	IN
cord-353633-a4pu6rlu	174	30	vitro	vitro	FW
cord-353633-a4pu6rlu	174	31	aggravates	aggravate	VBZ
cord-353633-a4pu6rlu	174	32	hepatocellular	hepatocellular	JJ
cord-353633-a4pu6rlu	174	33	growth	growth	NN
cord-353633-a4pu6rlu	174	34	and	and	CC
cord-353633-a4pu6rlu	174	35	viability	viability	NN
cord-353633-a4pu6rlu	174	36	[	[	-LRB-
cord-353633-a4pu6rlu	174	37	110	110	CD
cord-353633-a4pu6rlu	174	38	]	]	-RRB-
cord-353633-a4pu6rlu	174	39	.	.	.
cord-353633-a4pu6rlu	175	1	Identified	identify	VBN
cord-353633-a4pu6rlu	175	2	and	and	CC
cord-353633-a4pu6rlu	175	3	validated	validate	VBD
cord-353633-a4pu6rlu	175	4	through	through	IN
cord-353633-a4pu6rlu	175	5	whole	whole	JJ
cord-353633-a4pu6rlu	175	6	serum	serum	NN
cord-353633-a4pu6rlu	175	7	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	175	8	analysis	analysis	NN
cord-353633-a4pu6rlu	175	9	,	,	,
cord-353633-a4pu6rlu	175	10	lncRNA	lncRNA	NNP
cord-353633-a4pu6rlu	175	11	RP11	RP11	NNP
cord-353633-a4pu6rlu	175	12	-	-	HYPH
cord-353633-a4pu6rlu	175	13	128N14.5	128N14.5	NNP
cord-353633-a4pu6rlu	175	14	has	have	VBZ
cord-353633-a4pu6rlu	175	15	been	be	VBN
cord-353633-a4pu6rlu	175	16	linked	link	VBN
cord-353633-a4pu6rlu	175	17	to	to	IN
cord-353633-a4pu6rlu	175	18	NASH	NASH	NNP
cord-353633-a4pu6rlu	175	19	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	175	20	and	and	CC
cord-353633-a4pu6rlu	175	21	is	be	VBZ
cord-353633-a4pu6rlu	175	22	upregulated	upregulate	VBN
cord-353633-a4pu6rlu	175	23	in	in	IN
cord-353633-a4pu6rlu	175	24	NAS	NAS	NNP
cord-353633-a4pu6rlu	175	25	≥	≥	CD
cord-353633-a4pu6rlu	175	26	5	5	CD
cord-353633-a4pu6rlu	175	27	[	[	-LRB-
cord-353633-a4pu6rlu	175	28	99	99	CD
cord-353633-a4pu6rlu	175	29	]	]	-RRB-
cord-353633-a4pu6rlu	175	30	.	.	.
cord-353633-a4pu6rlu	176	1	Furthermore	furthermore	RB
cord-353633-a4pu6rlu	176	2	,	,	,
cord-353633-a4pu6rlu	176	3	transport	transport	NN
cord-353633-a4pu6rlu	176	4	RNA	RNA	NNP
cord-353633-a4pu6rlu	176	5	(	(	-LRB-
cord-353633-a4pu6rlu	176	6	tRNA	tRNA	NNP
cord-353633-a4pu6rlu	176	7	)	)	-RRB-
cord-353633-a4pu6rlu	176	8	profiling	profiling	NN
cord-353633-a4pu6rlu	176	9	pinpoints	pinpoint	VBZ
cord-353633-a4pu6rlu	176	10	the	the	DT
cord-353633-a4pu6rlu	176	11	differential	differential	JJ
cord-353633-a4pu6rlu	176	12	expression	expression	NN
cord-353633-a4pu6rlu	176	13	levels	level	NNS
cord-353633-a4pu6rlu	176	14	of	of	IN
cord-353633-a4pu6rlu	176	15	several	several	JJ
cord-353633-a4pu6rlu	176	16	anticodons	anticodon	NNS
cord-353633-a4pu6rlu	176	17	for	for	IN
cord-353633-a4pu6rlu	176	18	lysine	lysine	NN
cord-353633-a4pu6rlu	176	19	,	,	,
cord-353633-a4pu6rlu	176	20	aspartate	aspartate	NN
cord-353633-a4pu6rlu	176	21	and	and	CC
cord-353633-a4pu6rlu	176	22	glutamate	glutamate	NN
cord-353633-a4pu6rlu	176	23	in	in	IN
cord-353633-a4pu6rlu	176	24	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	176	25	,	,	,
cord-353633-a4pu6rlu	176	26	in	in	IN
cord-353633-a4pu6rlu	176	27	addition	addition	NN
cord-353633-a4pu6rlu	176	28	to	to	IN
cord-353633-a4pu6rlu	176	29	various	various	JJ
cord-353633-a4pu6rlu	176	30	mitochondrial	mitochondrial	NN
cord-353633-a4pu6rlu	176	31	and	and	CC
cord-353633-a4pu6rlu	176	32	amino	amino	NN
cord-353633-a4pu6rlu	176	33	acid	acid	NN
cord-353633-a4pu6rlu	177	1	tRNAs	tRNAs	.
cord-353633-a4pu6rlu	178	1	in	in	IN
cord-353633-a4pu6rlu	178	2	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	178	3	versus	versus	IN
cord-353633-a4pu6rlu	178	4	NASH	NASH	NNP
cord-353633-a4pu6rlu	178	5	and	and	CC
cord-353633-a4pu6rlu	178	6	NASH	NASH	NNP
cord-353633-a4pu6rlu	178	7	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	178	8	versus	versus	IN
cord-353633-a4pu6rlu	178	9	normal	normal	JJ
cord-353633-a4pu6rlu	178	10	respectively	respectively	RB
cord-353633-a4pu6rlu	178	11	[	[	-LRB-
cord-353633-a4pu6rlu	178	12	102	102	CD
cord-353633-a4pu6rlu	178	13	]	]	-RRB-
cord-353633-a4pu6rlu	178	14	.	.	.
cord-353633-a4pu6rlu	179	1	The	the	DT
cord-353633-a4pu6rlu	179	2	same	same	JJ
cord-353633-a4pu6rlu	179	3	study	study	NN
cord-353633-a4pu6rlu	179	4	has	have	VBZ
cord-353633-a4pu6rlu	179	5	also	also	RB
cord-353633-a4pu6rlu	179	6	compared	compare	VBN
cord-353633-a4pu6rlu	179	7	the	the	DT
cord-353633-a4pu6rlu	179	8	abundance	abundance	NN
cord-353633-a4pu6rlu	179	9	of	of	IN
cord-353633-a4pu6rlu	179	10	392	392	CD
cord-353633-a4pu6rlu	179	11	several	several	JJ
cord-353633-a4pu6rlu	179	12	small	small	JJ
cord-353633-a4pu6rlu	179	13	RNA	RNA	NNP
cord-353633-a4pu6rlu	179	14	molecules	molecule	NNS
cord-353633-a4pu6rlu	179	15	(	(	-LRB-
cord-353633-a4pu6rlu	179	16	ribosomal	ribosomal	JJ
cord-353633-a4pu6rlu	179	17	,	,	,
cord-353633-a4pu6rlu	179	18	small	small	JJ
cord-353633-a4pu6rlu	179	19	nuclear	nuclear	JJ
cord-353633-a4pu6rlu	179	20	and	and	CC
cord-353633-a4pu6rlu	179	21	nucleolar	nucleolar	NN
cord-353633-a4pu6rlu	179	22	)	)	-RRB-
cord-353633-a4pu6rlu	179	23	between	between	IN
cord-353633-a4pu6rlu	179	24	healthy	healthy	JJ
cord-353633-a4pu6rlu	179	25	,	,	,
cord-353633-a4pu6rlu	179	26	NASH	NASH	NNP
cord-353633-a4pu6rlu	179	27	and	and	CC
cord-353633-a4pu6rlu	179	28	cirrhotic	cirrhotic	JJ
cord-353633-a4pu6rlu	179	29	patients	patient	NNS
cord-353633-a4pu6rlu	179	30	[	[	-LRB-
cord-353633-a4pu6rlu	179	31	102	102	CD
cord-353633-a4pu6rlu	179	32	]	]	-RRB-
cord-353633-a4pu6rlu	179	33	.	.	.
cord-353633-a4pu6rlu	180	1	Various	various	JJ
cord-353633-a4pu6rlu	180	2	predictive	predictive	JJ
cord-353633-a4pu6rlu	180	3	modalities	modality	NNS
cord-353633-a4pu6rlu	180	4	involving	involve	VBG
cord-353633-a4pu6rlu	180	5	gene	gene	NN
cord-353633-a4pu6rlu	180	6	expression	expression	NN
cord-353633-a4pu6rlu	180	7	parameters	parameter	NNS
cord-353633-a4pu6rlu	180	8	,	,	,
cord-353633-a4pu6rlu	180	9	targeted	target	VBN
cord-353633-a4pu6rlu	180	10	measurements	measurement	NNS
cord-353633-a4pu6rlu	180	11	and	and	CC
cord-353633-a4pu6rlu	180	12	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	180	13	panels	panel	NNS
cord-353633-a4pu6rlu	180	14	with	with	IN
cord-353633-a4pu6rlu	180	15	increased	increase	VBN
cord-353633-a4pu6rlu	180	16	functionality	functionality	NN
cord-353633-a4pu6rlu	180	17	are	be	VBP
cord-353633-a4pu6rlu	180	18	based	base	VBN
cord-353633-a4pu6rlu	180	19	on	on	IN
cord-353633-a4pu6rlu	180	20	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	180	21	.	.	.
cord-353633-a4pu6rlu	181	1	In	in	IN
cord-353633-a4pu6rlu	181	2	general	general	JJ
cord-353633-a4pu6rlu	181	3	,	,	,
cord-353633-a4pu6rlu	181	4	the	the	DT
cord-353633-a4pu6rlu	181	5	reported	report	VBN
cord-353633-a4pu6rlu	181	6	accuracies	accuracy	NNS
cord-353633-a4pu6rlu	181	7	for	for	IN
cord-353633-a4pu6rlu	181	8	many	many	JJ
cord-353633-a4pu6rlu	181	9	of	of	IN
cord-353633-a4pu6rlu	181	10	these	these	DT
cord-353633-a4pu6rlu	181	11	tests	test	NNS
cord-353633-a4pu6rlu	182	1	J	J	NNP
cord-353633-a4pu6rlu	182	2	o	o	NN
cord-353633-a4pu6rlu	182	3	u	u	NN
cord-353633-a4pu6rlu	182	4	r	r	NN
cord-353633-a4pu6rlu	182	5	n	n	NN
cord-353633-a4pu6rlu	182	6	a	a	NN
cord-353633-a4pu6rlu	183	1	l	l	NN
cord-353633-a4pu6rlu	183	2	P	p	NN
cord-353633-a4pu6rlu	183	3	r	r	NN
cord-353633-a4pu6rlu	183	4	e	e	NN
cord-353633-a4pu6rlu	183	5	-p	-p	NN
cord-353633-a4pu6rlu	183	6	r	r	NN
cord-353633-a4pu6rlu	183	7	o	o	NN
cord-353633-a4pu6rlu	183	8	o	o	NN
cord-353633-a4pu6rlu	183	9	f	f	NN
cord-353633-a4pu6rlu	183	10	27	27	CD
cord-353633-a4pu6rlu	183	11	have	have	VBP
cord-353633-a4pu6rlu	183	12	been	be	VBN
cord-353633-a4pu6rlu	183	13	high	high	JJ
cord-353633-a4pu6rlu	183	14	for	for	IN
cord-353633-a4pu6rlu	183	15	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	183	16	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	183	17	or	or	CC
cord-353633-a4pu6rlu	183	18	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	183	19	from	from	IN
cord-353633-a4pu6rlu	183	20	healthy	healthy	JJ
cord-353633-a4pu6rlu	183	21	status	status	NN
cord-353633-a4pu6rlu	183	22	but	but	CC
cord-353633-a4pu6rlu	183	23	rather	rather	RB
cord-353633-a4pu6rlu	183	24	low	low	JJ
cord-353633-a4pu6rlu	183	25	for	for	IN
cord-353633-a4pu6rlu	183	26	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	183	27	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	183	28	from	from	IN
cord-353633-a4pu6rlu	183	29	NASH	NASH	NNP
cord-353633-a4pu6rlu	183	30	or	or	CC
cord-353633-a4pu6rlu	183	31	for	for	IN
cord-353633-a4pu6rlu	183	32	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	183	33	advanced	advanced	JJ
cord-353633-a4pu6rlu	183	34	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	183	35	.	.	.
cord-353633-a4pu6rlu	184	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	184	2	,	,	,
cord-353633-a4pu6rlu	184	3	even	even	RB
cord-353633-a4pu6rlu	184	4	the	the	DT
cord-353633-a4pu6rlu	184	5	most	most	RBS
cord-353633-a4pu6rlu	184	6	promising	promising	JJ
cord-353633-a4pu6rlu	184	7	studies	study	NNS
cord-353633-a4pu6rlu	184	8	,	,	,
cord-353633-a4pu6rlu	184	9	have	have	VBP
cord-353633-a4pu6rlu	184	10	not	not	RB
cord-353633-a4pu6rlu	184	11	been	be	VBN
cord-353633-a4pu6rlu	184	12	further	further	RB
cord-353633-a4pu6rlu	184	13	tested	test	VBN
cord-353633-a4pu6rlu	184	14	or	or	CC
cord-353633-a4pu6rlu	184	15	have	have	VBP
cord-353633-a4pu6rlu	184	16	performed	perform	VBN
cord-353633-a4pu6rlu	184	17	poorly	poorly	RB
cord-353633-a4pu6rlu	184	18	in	in	IN
cord-353633-a4pu6rlu	184	19	other	other	JJ
cord-353633-a4pu6rlu	184	20	cohorts	cohort	NNS
cord-353633-a4pu6rlu	184	21	.	.	.
cord-353633-a4pu6rlu	185	1	Among	among	IN
cord-353633-a4pu6rlu	185	2	them	-PRON-	PRP
cord-353633-a4pu6rlu	185	3	,	,	,
cord-353633-a4pu6rlu	185	4	predictive	predictive	JJ
cord-353633-a4pu6rlu	185	5	models	model	NNS
cord-353633-a4pu6rlu	185	6	based	base	VBN
cord-353633-a4pu6rlu	185	7	on	on	IN
cord-353633-a4pu6rlu	185	8	miRNAs	miRNAs	NNP
cord-353633-a4pu6rlu	185	9	have	have	VBP
cord-353633-a4pu6rlu	185	10	in	in	IN
cord-353633-a4pu6rlu	185	11	theory	theory	NN
cord-353633-a4pu6rlu	185	12	higher	high	JJR
cord-353633-a4pu6rlu	185	13	chances	chance	NNS
cord-353633-a4pu6rlu	185	14	to	to	TO
cord-353633-a4pu6rlu	185	15	be	be	VB
cord-353633-a4pu6rlu	185	16	robust	robust	JJ
cord-353633-a4pu6rlu	185	17	and	and	CC
cord-353633-a4pu6rlu	185	18	reproducible	reproducible	JJ
cord-353633-a4pu6rlu	185	19	,	,	,
cord-353633-a4pu6rlu	185	20	since	since	IN
cord-353633-a4pu6rlu	185	21	miRNAs	miRNAs	NNP
cord-353633-a4pu6rlu	185	22	can	can	MD
cord-353633-a4pu6rlu	185	23	withstand	withstand	VB
cord-353633-a4pu6rlu	185	24	numerous	numerous	JJ
cord-353633-a4pu6rlu	185	25	freeze	freeze	NN
cord-353633-a4pu6rlu	185	26	-	-	HYPH
cord-353633-a4pu6rlu	185	27	thaw	thaw	VB
cord-353633-a4pu6rlu	185	28	cycles	cycle	NNS
cord-353633-a4pu6rlu	185	29	and	and	CC
cord-353633-a4pu6rlu	185	30	long	long	JJ
cord-353633-a4pu6rlu	185	31	-	-	HYPH
cord-353633-a4pu6rlu	185	32	term	term	NN
cord-353633-a4pu6rlu	185	33	storage	storage	NN
cord-353633-a4pu6rlu	185	34	before	before	IN
cord-353633-a4pu6rlu	185	35	degrading	degrade	VBG
cord-353633-a4pu6rlu	185	36	[	[	-LRB-
cord-353633-a4pu6rlu	185	37	111	111	CD
cord-353633-a4pu6rlu	185	38	]	]	-RRB-
cord-353633-a4pu6rlu	185	39	.	.	.
cord-353633-a4pu6rlu	186	1	Several	several	JJ
cord-353633-a4pu6rlu	186	2	studies	study	NNS
cord-353633-a4pu6rlu	186	3	have	have	VBP
cord-353633-a4pu6rlu	186	4	identified	identify	VBN
cord-353633-a4pu6rlu	186	5	miR-122	miR-122	NNP
cord-353633-a4pu6rlu	186	6	as	as	IN
cord-353633-a4pu6rlu	186	7	a	a	DT
cord-353633-a4pu6rlu	186	8	potential	potential	JJ
cord-353633-a4pu6rlu	186	9	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	186	10	biomarker	biomarker	NN
cord-353633-a4pu6rlu	186	11	.	.	.
cord-353633-a4pu6rlu	187	1	Most	Most	JJS
cord-353633-a4pu6rlu	187	2	of	of	IN
cord-353633-a4pu6rlu	187	3	them	-PRON-	PRP
cord-353633-a4pu6rlu	187	4	have	have	VBP
cord-353633-a4pu6rlu	187	5	shown	show	VBN
cord-353633-a4pu6rlu	187	6	that	that	IN
cord-353633-a4pu6rlu	187	7	miR-122	miR-122	NNP
cord-353633-a4pu6rlu	187	8	alone	alone	JJ
cord-353633-a4pu6rlu	187	9	or	or	CC
cord-353633-a4pu6rlu	187	10	in	in	IN
cord-353633-a4pu6rlu	187	11	combination	combination	NN
cord-353633-a4pu6rlu	187	12	with	with	IN
cord-353633-a4pu6rlu	187	13	other	other	JJ
cord-353633-a4pu6rlu	187	14	miRNAs	miRNAs	NNP
cord-353633-a4pu6rlu	187	15	(	(	-LRB-
cord-353633-a4pu6rlu	187	16	e.g.	e.g.	NNP
cord-353633-a4pu6rlu	187	17	miR-1290	mir-1290	CD
cord-353633-a4pu6rlu	187	18	,	,	,
cord-353633-a4pu6rlu	187	19	miR-27	mir-27	NN
cord-353633-a4pu6rlu	187	20	,	,	,
cord-353633-a4pu6rlu	187	21	miR-192	miR-192	NNP
cord-353633-a4pu6rlu	187	22	,	,	,
cord-353633-a4pu6rlu	187	23	miR-34	miR-34	NNP
cord-353633-a4pu6rlu	187	24	,	,	,
cord-353633-a4pu6rlu	187	25	miR-99a	miR-99a	NNP
cord-353633-a4pu6rlu	187	26	)	)	-RRB-
cord-353633-a4pu6rlu	187	27	can	can	MD
cord-353633-a4pu6rlu	187	28	accurately	accurately	RB
cord-353633-a4pu6rlu	187	29	predict	predict	VB
cord-353633-a4pu6rlu	187	30	the	the	DT
cord-353633-a4pu6rlu	187	31	presence	presence	NN
cord-353633-a4pu6rlu	187	32	of	of	IN
cord-353633-a4pu6rlu	187	33	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	187	34	or	or	CC
cord-353633-a4pu6rlu	187	35	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	187	36	,	,	,
cord-353633-a4pu6rlu	187	37	but	but	CC
cord-353633-a4pu6rlu	187	38	they	-PRON-	PRP
cord-353633-a4pu6rlu	187	39	all	all	DT
cord-353633-a4pu6rlu	187	40	perform	perform	VBP
cord-353633-a4pu6rlu	187	41	inadequately	inadequately	RB
cord-353633-a4pu6rlu	187	42	when	when	WRB
cord-353633-a4pu6rlu	187	43	trying	try	VBG
cord-353633-a4pu6rlu	187	44	to	to	TO
cord-353633-a4pu6rlu	187	45	differentiate	differentiate	VB
cord-353633-a4pu6rlu	187	46	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	187	47	from	from	IN
cord-353633-a4pu6rlu	187	48	NASH	NASH	NNP
cord-353633-a4pu6rlu	187	49	[	[	-LRB-
cord-353633-a4pu6rlu	187	50	103	103	CD
cord-353633-a4pu6rlu	187	51	,	,	,
cord-353633-a4pu6rlu	187	52	108	108	CD
cord-353633-a4pu6rlu	187	53	,	,	,
cord-353633-a4pu6rlu	187	54	[	[	-LRB-
cord-353633-a4pu6rlu	187	55	112	112	CD
cord-353633-a4pu6rlu	187	56	]	]	-RRB-
cord-353633-a4pu6rlu	187	57	[	[	-LRB-
cord-353633-a4pu6rlu	187	58	113	113	CD
cord-353633-a4pu6rlu	187	59	]	]	-RRB-
cord-353633-a4pu6rlu	187	60	[	[	-LRB-
cord-353633-a4pu6rlu	187	61	114	114	CD
cord-353633-a4pu6rlu	187	62	]	]	-RRB-
cord-353633-a4pu6rlu	187	63	(	(	-LRB-
cord-353633-a4pu6rlu	187	64	Table	table	NN
cord-353633-a4pu6rlu	187	65	2	2	CD
cord-353633-a4pu6rlu	187	66	)	)	-RRB-
cord-353633-a4pu6rlu	187	67	.	.	.
cord-353633-a4pu6rlu	188	1	with	with	IN
cord-353633-a4pu6rlu	188	2	other	other	JJ
cord-353633-a4pu6rlu	188	3	proteins	protein	NNS
cord-353633-a4pu6rlu	188	4	in	in	IN
cord-353633-a4pu6rlu	188	5	their	-PRON-	PRP$
cord-353633-a4pu6rlu	188	6	algorithm	algorithm	NN
cord-353633-a4pu6rlu	188	7	.	.	.
cord-353633-a4pu6rlu	189	1	Among	among	IN
cord-353633-a4pu6rlu	189	2	them	-PRON-	PRP
cord-353633-a4pu6rlu	189	3	,	,	,
cord-353633-a4pu6rlu	189	4	NIS4	NIS4	NNP
cord-353633-a4pu6rlu	189	5	TM	TM	NNP
cord-353633-a4pu6rlu	189	6	,	,	,
cord-353633-a4pu6rlu	189	7	which	which	WDT
cord-353633-a4pu6rlu	189	8	includes	include	VBZ
cord-353633-a4pu6rlu	189	9	miR-34a	miR-34a	NNP
cord-353633-a4pu6rlu	189	10	,	,	,
cord-353633-a4pu6rlu	189	11	alpha-2-macroglobulin	alpha-2-macroglobulin	NNP
cord-353633-a4pu6rlu	189	12	,	,	,
cord-353633-a4pu6rlu	189	13	chitinase-3-like	chitinase-3-like	NNP
cord-353633-a4pu6rlu	189	14	protein	protein	NN
cord-353633-a4pu6rlu	189	15	1	1	CD
cord-353633-a4pu6rlu	189	16	,	,	,
cord-353633-a4pu6rlu	189	17	has	have	VBZ
cord-353633-a4pu6rlu	189	18	been	be	VBN
cord-353633-a4pu6rlu	189	19	recently	recently	RB
cord-353633-a4pu6rlu	189	20	tested	test	VBN
cord-353633-a4pu6rlu	189	21	in	in	IN
cord-353633-a4pu6rlu	189	22	a	a	DT
cord-353633-a4pu6rlu	189	23	population	population	NN
cord-353633-a4pu6rlu	189	24	with	with	IN
cord-353633-a4pu6rlu	189	25	type	type	NN
cord-353633-a4pu6rlu	189	26	2	2	CD
cord-353633-a4pu6rlu	189	27	diabetes	diabetes	NN
cord-353633-a4pu6rlu	189	28	(	(	-LRB-
cord-353633-a4pu6rlu	189	29	n=275	n=275	NNP
cord-353633-a4pu6rlu	189	30	)	)	-RRB-
cord-353633-a4pu6rlu	189	31	,	,	,
cord-353633-a4pu6rlu	189	32	showing	show	VBG
cord-353633-a4pu6rlu	189	33	an	an	DT
cord-353633-a4pu6rlu	189	34	AUROC	AUROC	NNP
cord-353633-a4pu6rlu	189	35	performance	performance	NN
cord-353633-a4pu6rlu	189	36	of	of	IN
cord-353633-a4pu6rlu	189	37	0.801	0.801	CD
cord-353633-a4pu6rlu	189	38	for	for	IN
cord-353633-a4pu6rlu	189	39	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	189	40	advanced	advance	VBN
cord-353633-a4pu6rlu	189	41	NASH	NASH	NNP
cord-353633-a4pu6rlu	189	42	(	(	-LRB-
cord-353633-a4pu6rlu	189	43	NAS≥4	NAS≥4	NNP
cord-353633-a4pu6rlu	189	44	)	)	-RRB-
cord-353633-a4pu6rlu	189	45	and	and	CC
cord-353633-a4pu6rlu	189	46	significant	significant	JJ
cord-353633-a4pu6rlu	189	47	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	189	48	(	(	-LRB-
cord-353633-a4pu6rlu	189	49	F≥2	F≥2	NNS
cord-353633-a4pu6rlu	189	50	)	)	-RRB-
cord-353633-a4pu6rlu	189	51	,	,	,
cord-353633-a4pu6rlu	189	52	which	which	WDT
cord-353633-a4pu6rlu	189	53	was	be	VBD
cord-353633-a4pu6rlu	189	54	also	also	RB
cord-353633-a4pu6rlu	189	55	higher	high	JJR
cord-353633-a4pu6rlu	189	56	than	than	IN
cord-353633-a4pu6rlu	189	57	in	in	IN
cord-353633-a4pu6rlu	189	58	other	other	JJ
cord-353633-a4pu6rlu	189	59	tests	test	NNS
cord-353633-a4pu6rlu	189	60	,	,	,
cord-353633-a4pu6rlu	189	61	such	such	JJ
cord-353633-a4pu6rlu	189	62	as	as	IN
cord-353633-a4pu6rlu	189	63	FIB4	FIB4	NNP
cord-353633-a4pu6rlu	189	64	(	(	-LRB-
cord-353633-a4pu6rlu	189	65	0.704	0.704	CD
cord-353633-a4pu6rlu	189	66	)	)	-RRB-
cord-353633-a4pu6rlu	189	67	,	,	,
cord-353633-a4pu6rlu	189	68	ELF	ELF	NNP
cord-353633-a4pu6rlu	189	69	(	(	-LRB-
cord-353633-a4pu6rlu	189	70	0.704	0.704	CD
cord-353633-a4pu6rlu	189	71	)	)	-RRB-
cord-353633-a4pu6rlu	189	72	or	or	CC
cord-353633-a4pu6rlu	189	73	Fibrometer	Fibrometer	NNP
cord-353633-a4pu6rlu	189	74	(	(	-LRB-
cord-353633-a4pu6rlu	189	75	0.678	0.678	CD
cord-353633-a4pu6rlu	189	76	)	)	-RRB-
cord-353633-a4pu6rlu	189	77	but	but	CC
cord-353633-a4pu6rlu	189	78	probably	probably	RB
cord-353633-a4pu6rlu	189	79	still	still	RB
cord-353633-a4pu6rlu	189	80	suboptimal	suboptimal	JJ
cord-353633-a4pu6rlu	189	81	[	[	-LRB-
cord-353633-a4pu6rlu	189	82	115	115	CD
cord-353633-a4pu6rlu	189	83	]	]	-RRB-
cord-353633-a4pu6rlu	189	84	.	.	.
cord-353633-a4pu6rlu	190	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	190	2	,	,	,
cord-353633-a4pu6rlu	190	3	the	the	DT
cord-353633-a4pu6rlu	190	4	same	same	JJ
cord-353633-a4pu6rlu	190	5	test	test	NN
cord-353633-a4pu6rlu	190	6	demonstrated	demonstrate	VBD
cord-353633-a4pu6rlu	190	7	76	76	CD
cord-353633-a4pu6rlu	190	8	%	%	NN
cord-353633-a4pu6rlu	190	9	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	190	10	and	and	CC
cord-353633-a4pu6rlu	190	11	specificity	specificity	NN
cord-353633-a4pu6rlu	190	12	in	in	IN
cord-353633-a4pu6rlu	190	13	detecting	detect	VBG
cord-353633-a4pu6rlu	190	14	NASH	NASH	NNP
cord-353633-a4pu6rlu	190	15	patients	patient	NNS
cord-353633-a4pu6rlu	190	16	at	at	IN
cord-353633-a4pu6rlu	190	17	risk	risk	NN
cord-353633-a4pu6rlu	190	18	of	of	IN
cord-353633-a4pu6rlu	190	19	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	190	20	[	[	-LRB-
cord-353633-a4pu6rlu	190	21	116	116	CD
cord-353633-a4pu6rlu	190	22	]	]	-RRB-
cord-353633-a4pu6rlu	190	23	.	.	.
cord-353633-a4pu6rlu	191	1	Another	another	DT
cord-353633-a4pu6rlu	191	2	model	model	NN
cord-353633-a4pu6rlu	191	3	integrating	integrate	VBG
cord-353633-a4pu6rlu	191	4	miR-122	miR-122	NNP
cord-353633-a4pu6rlu	191	5	,	,	,
cord-353633-a4pu6rlu	191	6	miR-192	miR-192	NNP
cord-353633-a4pu6rlu	191	7	,	,	,
cord-353633-a4pu6rlu	191	8	miR-21	miR-21	NNP
cord-353633-a4pu6rlu	191	9	and	and	CC
cord-353633-a4pu6rlu	191	10	CK-18	CK-18	NNP
cord-353633-a4pu6rlu	191	11	fragments	fragment	NNS
cord-353633-a4pu6rlu	191	12	,	,	,
cord-353633-a4pu6rlu	191	13	can	can	MD
cord-353633-a4pu6rlu	191	14	differentiate	differentiate	VB
cord-353633-a4pu6rlu	191	15	NASH	NASH	NNP
cord-353633-a4pu6rlu	191	16	from	from	IN
cord-353633-a4pu6rlu	191	17	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	192	1	(	(	-LRB-
cord-353633-a4pu6rlu	192	2	AUROC	AUROC	NNP
cord-353633-a4pu6rlu	192	3	=	=	SYM
cord-353633-a4pu6rlu	192	4	0.83	0.83	CD
cord-353633-a4pu6rlu	192	5	)	)	-RRB-
cord-353633-a4pu6rlu	193	1	[	[	-LRB-
cord-353633-a4pu6rlu	193	2	117	117	CD
cord-353633-a4pu6rlu	193	3	]	]	-RRB-
cord-353633-a4pu6rlu	194	1	(	(	-LRB-
cord-353633-a4pu6rlu	194	2	Table	table	NN
cord-353633-a4pu6rlu	194	3	2	2	CD
cord-353633-a4pu6rlu	194	4	)	)	-RRB-
cord-353633-a4pu6rlu	194	5	.	.	.
cord-353633-a4pu6rlu	195	1	New	new	JJ
cord-353633-a4pu6rlu	195	2	frontiers	frontier	NNS
cord-353633-a4pu6rlu	195	3	,	,	,
cord-353633-a4pu6rlu	195	4	such	such	JJ
cord-353633-a4pu6rlu	195	5	as	as	IN
cord-353633-a4pu6rlu	195	6	circular	circular	JJ
cord-353633-a4pu6rlu	195	7	RNA	RNA	NNP
cord-353633-a4pu6rlu	195	8	(	(	-LRB-
cord-353633-a4pu6rlu	195	9	circRNA	circRNA	NNP
cord-353633-a4pu6rlu	195	10	)	)	-RRB-
cord-353633-a4pu6rlu	195	11	transcriptomics	transcriptomics	NNP
cord-353633-a4pu6rlu	195	12	,	,	,
cord-353633-a4pu6rlu	195	13	are	be	VBP
cord-353633-a4pu6rlu	195	14	being	be	VBG
cord-353633-a4pu6rlu	195	15	investigated	investigate	VBN
cord-353633-a4pu6rlu	195	16	in	in	IN
cord-353633-a4pu6rlu	195	17	animals	animal	NNS
cord-353633-a4pu6rlu	195	18	.	.	.
cord-353633-a4pu6rlu	196	1	Researchers	researcher	NNS
cord-353633-a4pu6rlu	196	2	have	have	VBP
cord-353633-a4pu6rlu	196	3	already	already	RB
cord-353633-a4pu6rlu	196	4	mapped	map	VBN
cord-353633-a4pu6rlu	196	5	and	and	CC
cord-353633-a4pu6rlu	196	6	correlated	correlate	VBN
cord-353633-a4pu6rlu	196	7	J	J	NNP
cord-353633-a4pu6rlu	196	8	o	o	NN
cord-353633-a4pu6rlu	196	9	u	u	NN
cord-353633-a4pu6rlu	196	10	r	r	NN
cord-353633-a4pu6rlu	196	11	n	n	NN
cord-353633-a4pu6rlu	196	12	a	a	DT
cord-353633-a4pu6rlu	196	13	l	l	NN
cord-353633-a4pu6rlu	196	14	P	p	NN
cord-353633-a4pu6rlu	196	15	r	r	NN
cord-353633-a4pu6rlu	196	16	e	e	NN
cord-353633-a4pu6rlu	196	17	-p	-p	NN
cord-353633-a4pu6rlu	197	1	r	r	NN
cord-353633-a4pu6rlu	197	2	o	o	NN
cord-353633-a4pu6rlu	197	3	o	o	NN
cord-353633-a4pu6rlu	197	4	f	f	NN
cord-353633-a4pu6rlu	197	5	28	28	CD
cord-353633-a4pu6rlu	197	6	circRNA	circRNA	NNP
cord-353633-a4pu6rlu	197	7	species	specie	NNS
cord-353633-a4pu6rlu	197	8	and	and	CC
cord-353633-a4pu6rlu	197	9	their	-PRON-	PRP$
cord-353633-a4pu6rlu	197	10	corresponding	corresponding	JJ
cord-353633-a4pu6rlu	197	11	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	197	12	pathways	pathway	NNS
cord-353633-a4pu6rlu	197	13	in	in	IN
cord-353633-a4pu6rlu	197	14	mouse	mouse	NN
cord-353633-a4pu6rlu	197	15	models	model	NNS
cord-353633-a4pu6rlu	197	16	of	of	IN
cord-353633-a4pu6rlu	197	17	NASH	NASH	NNP
cord-353633-a4pu6rlu	197	18	,	,	,
cord-353633-a4pu6rlu	197	19	showcasing	showcase	VBG
cord-353633-a4pu6rlu	197	20	their	-PRON-	PRP$
cord-353633-a4pu6rlu	197	21	associations	association	NNS
cord-353633-a4pu6rlu	197	22	with	with	IN
cord-353633-a4pu6rlu	197	23	metabolism	metabolism	NN
cord-353633-a4pu6rlu	197	24	[	[	-LRB-
cord-353633-a4pu6rlu	197	25	118	118	CD
cord-353633-a4pu6rlu	197	26	]	]	-RRB-
cord-353633-a4pu6rlu	197	27	and	and	CC
cord-353633-a4pu6rlu	197	28	stellate	stellate	JJ
cord-353633-a4pu6rlu	197	29	cell	cell	NN
cord-353633-a4pu6rlu	197	30	activation	activation	NN
cord-353633-a4pu6rlu	197	31	[	[	-LRB-
cord-353633-a4pu6rlu	197	32	119	119	CD
cord-353633-a4pu6rlu	197	33	]	]	-RRB-
cord-353633-a4pu6rlu	197	34	.	.	.
cord-353633-a4pu6rlu	198	1	Yet	yet	CC
cord-353633-a4pu6rlu	198	2	whether	whether	IN
cord-353633-a4pu6rlu	198	3	these	these	DT
cord-353633-a4pu6rlu	198	4	results	result	NNS
cord-353633-a4pu6rlu	198	5	could	could	MD
cord-353633-a4pu6rlu	198	6	yield	yield	VB
cord-353633-a4pu6rlu	198	7	meaningful	meaningful	JJ
cord-353633-a4pu6rlu	198	8	conclusions	conclusion	NNS
cord-353633-a4pu6rlu	198	9	that	that	WDT
cord-353633-a4pu6rlu	198	10	can	can	MD
cord-353633-a4pu6rlu	198	11	be	be	VB
cord-353633-a4pu6rlu	198	12	extrapolated	extrapolate	VBN
cord-353633-a4pu6rlu	198	13	in	in	IN
cord-353633-a4pu6rlu	198	14	human	human	JJ
cord-353633-a4pu6rlu	198	15	cohorts	cohort	NNS
cord-353633-a4pu6rlu	198	16	remains	remain	VBZ
cord-353633-a4pu6rlu	198	17	unclear	unclear	JJ
cord-353633-a4pu6rlu	198	18	.	.	.
cord-353633-a4pu6rlu	199	1	Other	other	JJ
cord-353633-a4pu6rlu	199	2	prospective	prospective	JJ
cord-353633-a4pu6rlu	199	3	research	research	NN
cord-353633-a4pu6rlu	199	4	questions	question	NNS
cord-353633-a4pu6rlu	199	5	in	in	IN
cord-353633-a4pu6rlu	199	6	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	199	7	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	199	8	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	199	9	concern	concern	NN
cord-353633-a4pu6rlu	199	10	alternative	alternative	JJ
cord-353633-a4pu6rlu	199	11	RNA	RNA	NNP
cord-353633-a4pu6rlu	199	12	splicing	splicing	NN
cord-353633-a4pu6rlu	199	13	[	[	-LRB-
cord-353633-a4pu6rlu	199	14	120	120	CD
cord-353633-a4pu6rlu	199	15	]	]	-RRB-
cord-353633-a4pu6rlu	199	16	and	and	CC
cord-353633-a4pu6rlu	199	17	the	the	DT
cord-353633-a4pu6rlu	199	18	scrutiny	scrutiny	NN
cord-353633-a4pu6rlu	199	19	of	of	IN
cord-353633-a4pu6rlu	199	20	unexplored	unexplored	JJ
cord-353633-a4pu6rlu	199	21	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	199	22	components	component	NNS
cord-353633-a4pu6rlu	199	23	,	,	,
cord-353633-a4pu6rlu	199	24	such	such	JJ
cord-353633-a4pu6rlu	199	25	as	as	IN
cord-353633-a4pu6rlu	199	26	CD24	CD24	NNP
cord-353633-a4pu6rlu	199	27	[	[	-LRB-
cord-353633-a4pu6rlu	199	28	92	92	CD
cord-353633-a4pu6rlu	199	29	]	]	-RRB-
cord-353633-a4pu6rlu	199	30	.	.	.
cord-353633-a4pu6rlu	200	1	Curative	curative	JJ
cord-353633-a4pu6rlu	200	2	and	and	CC
cord-353633-a4pu6rlu	200	3	bedside	bedside	NN
cord-353633-a4pu6rlu	200	4	implications	implication	NNS
cord-353633-a4pu6rlu	200	5	of	of	IN
cord-353633-a4pu6rlu	200	6	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	200	7	in	in	IN
cord-353633-a4pu6rlu	200	8	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	200	9	are	be	VBP
cord-353633-a4pu6rlu	200	10	considerably	considerably	RB
cord-353633-a4pu6rlu	200	11	limited	limited	JJ
cord-353633-a4pu6rlu	200	12	.	.	.
cord-353633-a4pu6rlu	201	1	From	from	IN
cord-353633-a4pu6rlu	201	2	an	an	DT
cord-353633-a4pu6rlu	201	3	interspecies	interspecies	NN
cord-353633-a4pu6rlu	201	4	aspect	aspect	NN
cord-353633-a4pu6rlu	201	5	,	,	,
cord-353633-a4pu6rlu	201	6	the	the	DT
cord-353633-a4pu6rlu	201	7	human	human	JJ
cord-353633-a4pu6rlu	201	8	and	and	CC
cord-353633-a4pu6rlu	201	9	murine	murine	JJ
cord-353633-a4pu6rlu	201	10	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	201	11	transcriptomes	transcriptome	NNS
cord-353633-a4pu6rlu	201	12	are	be	VBP
cord-353633-a4pu6rlu	201	13	largely	largely	RB
cord-353633-a4pu6rlu	201	14	dissimilar	dissimilar	JJ
cord-353633-a4pu6rlu	201	15	,	,	,
cord-353633-a4pu6rlu	201	16	yet	yet	CC
cord-353633-a4pu6rlu	201	17	their	-PRON-	PRP$
cord-353633-a4pu6rlu	201	18	likelihood	likelihood	NN
cord-353633-a4pu6rlu	201	19	increases	increase	NNS
cord-353633-a4pu6rlu	201	20	in	in	IN
cord-353633-a4pu6rlu	201	21	murine	murine	JJ
cord-353633-a4pu6rlu	201	22	models	model	NNS
cord-353633-a4pu6rlu	201	23	following	follow	VBG
cord-353633-a4pu6rlu	201	24	high	high	JJ
cord-353633-a4pu6rlu	201	25	-	-	HYPH
cord-353633-a4pu6rlu	201	26	fat	fat	NN
cord-353633-a4pu6rlu	201	27	diets	diet	NNS
cord-353633-a4pu6rlu	201	28	[	[	-LRB-
cord-353633-a4pu6rlu	201	29	90	90	CD
cord-353633-a4pu6rlu	201	30	]	]	-RRB-
cord-353633-a4pu6rlu	201	31	.	.	.
cord-353633-a4pu6rlu	202	1	Hence	hence	RB
cord-353633-a4pu6rlu	202	2	the	the	DT
cord-353633-a4pu6rlu	202	3	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	202	4	signatures	signature	NNS
cord-353633-a4pu6rlu	202	5	of	of	IN
cord-353633-a4pu6rlu	202	6	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	202	7	or	or	CC
cord-353633-a4pu6rlu	202	8	NASH	NASH	NNP
cord-353633-a4pu6rlu	202	9	as	as	RB
cord-353633-a4pu6rlu	202	10	well	well	RB
cord-353633-a4pu6rlu	202	11	as	as	IN
cord-353633-a4pu6rlu	202	12	the	the	DT
cord-353633-a4pu6rlu	202	13	organic	organic	JJ
cord-353633-a4pu6rlu	202	14	transcriptomic	transcriptomic	JJ
cord-353633-a4pu6rlu	202	15	responses	response	NNS
cord-353633-a4pu6rlu	202	16	to	to	IN
cord-353633-a4pu6rlu	202	17	relevant	relevant	JJ
cord-353633-a4pu6rlu	202	18	treatments	treatment	NNS
cord-353633-a4pu6rlu	202	19	for	for	IN
cord-353633-a4pu6rlu	202	20	liver	liver	NN
cord-353633-a4pu6rlu	202	21	disease	disease	NN
cord-353633-a4pu6rlu	202	22	can	can	MD
cord-353633-a4pu6rlu	202	23	be	be	VB
cord-353633-a4pu6rlu	202	24	evaluated	evaluate	VBN
cord-353633-a4pu6rlu	202	25	by	by	IN
cord-353633-a4pu6rlu	202	26	numerous	numerous	JJ
cord-353633-a4pu6rlu	202	27	available	available	JJ
cord-353633-a4pu6rlu	202	28	pre	pre	JJ
cord-353633-a4pu6rlu	202	29	-	-	JJ
cord-353633-a4pu6rlu	202	30	clinical	clinical	JJ
cord-353633-a4pu6rlu	202	31	in	in	IN
cord-353633-a4pu6rlu	202	32	vitro	vitro	FW
cord-353633-a4pu6rlu	202	33	prototypes	prototype	NNS
cord-353633-a4pu6rlu	202	34	and	and	CC
cord-353633-a4pu6rlu	202	35	animal	animal	NN
cord-353633-a4pu6rlu	202	36	models	model	NNS
cord-353633-a4pu6rlu	202	37	[	[	-LRB-
cord-353633-a4pu6rlu	202	38	121	121	CD
cord-353633-a4pu6rlu	202	39	]	]	-RRB-
cord-353633-a4pu6rlu	202	40	.	.	.
cord-353633-a4pu6rlu	203	1	For	for	IN
cord-353633-a4pu6rlu	203	2	instance	instance	NN
cord-353633-a4pu6rlu	203	3	,	,	,
cord-353633-a4pu6rlu	203	4	mapping	mapping	NN
cord-353633-a4pu6rlu	203	5	of	of	IN
cord-353633-a4pu6rlu	203	6	the	the	DT
cord-353633-a4pu6rlu	203	7	murine	murine	JJ
cord-353633-a4pu6rlu	203	8	NASH	NASH	NNP
cord-353633-a4pu6rlu	203	9	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	203	10	demonstrated	demonstrate	VBD
cord-353633-a4pu6rlu	203	11	an	an	DT
cord-353633-a4pu6rlu	203	12	increase	increase	NN
cord-353633-a4pu6rlu	203	13	in	in	IN
cord-353633-a4pu6rlu	203	14	the	the	DT
cord-353633-a4pu6rlu	203	15	levels	level	NNS
cord-353633-a4pu6rlu	203	16	of	of	IN
cord-353633-a4pu6rlu	203	17	Tsukushi	Tsukushi	NNP
cord-353633-a4pu6rlu	203	18	,	,	,
cord-353633-a4pu6rlu	203	19	a	a	DT
cord-353633-a4pu6rlu	203	20	novel	novel	JJ
cord-353633-a4pu6rlu	203	21	adipose	adipose	NN
cord-353633-a4pu6rlu	203	22	-	-	HYPH
cord-353633-a4pu6rlu	203	23	related	relate	VBN
cord-353633-a4pu6rlu	203	24	thermogenetic	thermogenetic	JJ
cord-353633-a4pu6rlu	203	25	and	and	CC
cord-353633-a4pu6rlu	203	26	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	203	27	hepatokine	hepatokine	NN
cord-353633-a4pu6rlu	203	28	.	.	.
cord-353633-a4pu6rlu	204	1	Subsequent	subsequent	JJ
cord-353633-a4pu6rlu	204	2	silencing	silencing	NN
cord-353633-a4pu6rlu	204	3	of	of	IN
cord-353633-a4pu6rlu	204	4	Tsukushi	Tsukushi	NNP
cord-353633-a4pu6rlu	204	5	improved	improve	VBD
cord-353633-a4pu6rlu	204	6	NASH	NASH	NNP
cord-353633-a4pu6rlu	204	7	and	and	CC
cord-353633-a4pu6rlu	204	8	attenuated	attenuate	VBD
cord-353633-a4pu6rlu	204	9	the	the	DT
cord-353633-a4pu6rlu	204	10	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	204	11	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	204	12	alterations	alteration	NNS
cord-353633-a4pu6rlu	204	13	associated	associate	VBN
cord-353633-a4pu6rlu	204	14	with	with	IN
cord-353633-a4pu6rlu	204	15	it	-PRON-	PRP
cord-353633-a4pu6rlu	204	16	[	[	-LRB-
cord-353633-a4pu6rlu	204	17	122	122	CD
cord-353633-a4pu6rlu	204	18	]	]	-RRB-
cord-353633-a4pu6rlu	204	19	.	.	.
cord-353633-a4pu6rlu	205	1	Transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	205	2	were	be	VBD
cord-353633-a4pu6rlu	205	3	also	also	RB
cord-353633-a4pu6rlu	205	4	implemented	implement	VBN
cord-353633-a4pu6rlu	205	5	in	in	IN
cord-353633-a4pu6rlu	205	6	recent	recent	JJ
cord-353633-a4pu6rlu	205	7	murine	murine	JJ
cord-353633-a4pu6rlu	205	8	models	model	NNS
cord-353633-a4pu6rlu	205	9	assessing	assess	VBG
cord-353633-a4pu6rlu	205	10	the	the	DT
cord-353633-a4pu6rlu	205	11	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	205	12	-	-	HYPH
cord-353633-a4pu6rlu	205	13	related	relate	VBN
cord-353633-a4pu6rlu	205	14	role	role	NN
cord-353633-a4pu6rlu	205	15	of	of	IN
cord-353633-a4pu6rlu	205	16	Poly	Poly	NNP
cord-353633-a4pu6rlu	205	17	rC	rC	NNP
cord-353633-a4pu6rlu	205	18	binding	bind	VBG
cord-353633-a4pu6rlu	205	19	protein	protein	NN
cord-353633-a4pu6rlu	205	20	1	1	CD
cord-353633-a4pu6rlu	205	21	,	,	,
cord-353633-a4pu6rlu	205	22	a	a	DT
cord-353633-a4pu6rlu	205	23	cytosolic	cytosolic	JJ
cord-353633-a4pu6rlu	205	24	iron	iron	NN
cord-353633-a4pu6rlu	205	25	chaperone	chaperone	NN
cord-353633-a4pu6rlu	205	26	,	,	,
cord-353633-a4pu6rlu	205	27	whose	whose	WP$
cord-353633-a4pu6rlu	205	28	deficiency	deficiency	NN
cord-353633-a4pu6rlu	205	29	exacerbates	exacerbate	VBZ
cord-353633-a4pu6rlu	205	30	steatosis	steatosis	NN
cord-353633-a4pu6rlu	205	31	and	and	CC
cord-353633-a4pu6rlu	205	32	inflammation	inflammation	NN
cord-353633-a4pu6rlu	205	33	,	,	,
cord-353633-a4pu6rlu	205	34	increases	increase	VBZ
cord-353633-a4pu6rlu	205	35	lipid	lipid	NN
cord-353633-a4pu6rlu	205	36	biosynthesis	biosynthesis	NN
cord-353633-a4pu6rlu	205	37	and	and	CC
cord-353633-a4pu6rlu	205	38	oxidative	oxidative	JJ
cord-353633-a4pu6rlu	205	39	stress	stress	NN
cord-353633-a4pu6rlu	205	40	pathway	pathway	NN
cord-353633-a4pu6rlu	205	41	expression	expression	NN
cord-353633-a4pu6rlu	205	42	levels	level	NNS
cord-353633-a4pu6rlu	205	43	,	,	,
cord-353633-a4pu6rlu	205	44	and	and	CC
cord-353633-a4pu6rlu	205	45	is	be	VBZ
cord-353633-a4pu6rlu	205	46	treated	treat	VBN
cord-353633-a4pu6rlu	205	47	via	via	IN
cord-353633-a4pu6rlu	205	48	reduced	reduce	VBN
cord-353633-a4pu6rlu	205	49	iron	iron	NN
cord-353633-a4pu6rlu	205	50	intake	intake	NN
cord-353633-a4pu6rlu	205	51	and	and	CC
cord-353633-a4pu6rlu	205	52	vitamin	vitamin	NN
cord-353633-a4pu6rlu	205	53	E	e	NN
cord-353633-a4pu6rlu	205	54	supplementation	supplementation	NN
cord-353633-a4pu6rlu	205	55	[	[	-LRB-
cord-353633-a4pu6rlu	205	56	123	123	CD
cord-353633-a4pu6rlu	205	57	]	]	-RRB-
cord-353633-a4pu6rlu	205	58	.	.	.
cord-353633-a4pu6rlu	206	1	Lastly	lastly	RB
cord-353633-a4pu6rlu	206	2	,	,	,
cord-353633-a4pu6rlu	206	3	in	in	IN
cord-353633-a4pu6rlu	206	4	view	view	NN
cord-353633-a4pu6rlu	206	5	of	of	IN
cord-353633-a4pu6rlu	206	6	the	the	DT
cord-353633-a4pu6rlu	206	7	COVID-19	COVID-19	NNP
cord-353633-a4pu6rlu	206	8	pandemic	pandemic	NN
cord-353633-a4pu6rlu	206	9	,	,	,
cord-353633-a4pu6rlu	206	10	the	the	DT
cord-353633-a4pu6rlu	206	11	expression	expression	NN
cord-353633-a4pu6rlu	206	12	levels	level	NNS
cord-353633-a4pu6rlu	206	13	of	of	IN
cord-353633-a4pu6rlu	206	14	4	4	CD
cord-353633-a4pu6rlu	206	15	SARS	SARS	NNP
cord-353633-a4pu6rlu	206	16	-	-	HYPH
cord-353633-a4pu6rlu	206	17	J	J	NNP
cord-353633-a4pu6rlu	206	18	o	o	NN
cord-353633-a4pu6rlu	206	19	u	u	NN
cord-353633-a4pu6rlu	206	20	r	r	NN
cord-353633-a4pu6rlu	206	21	n	n	NN
cord-353633-a4pu6rlu	206	22	a	a	DT
cord-353633-a4pu6rlu	206	23	l	l	NN
cord-353633-a4pu6rlu	206	24	P	p	NN
cord-353633-a4pu6rlu	206	25	r	r	NN
cord-353633-a4pu6rlu	206	26	e	e	NN
cord-353633-a4pu6rlu	206	27	-p	-p	NN
cord-353633-a4pu6rlu	206	28	r	r	NN
cord-353633-a4pu6rlu	206	29	o	o	NN
cord-353633-a4pu6rlu	207	1	o	o	NNP
cord-353633-a4pu6rlu	207	2	f	f	NNP
cord-353633-a4pu6rlu	207	3	29	29	CD
cord-353633-a4pu6rlu	207	4	COV-2	COV-2	NNP
cord-353633-a4pu6rlu	207	5	entry	entry	NN
cord-353633-a4pu6rlu	207	6	proteins	protein	NNS
cord-353633-a4pu6rlu	207	7	were	be	VBD
cord-353633-a4pu6rlu	207	8	assessed	assess	VBN
cord-353633-a4pu6rlu	207	9	by	by	IN
cord-353633-a4pu6rlu	207	10	liver	liver	NN
cord-353633-a4pu6rlu	207	11	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	207	12	in	in	IN
cord-353633-a4pu6rlu	207	13	human	human	JJ
cord-353633-a4pu6rlu	207	14	and	and	CC
cord-353633-a4pu6rlu	207	15	murine	murine	JJ
cord-353633-a4pu6rlu	207	16	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	207	17	and	and	CC
cord-353633-a4pu6rlu	207	18	NASH	NASH	NNP
cord-353633-a4pu6rlu	207	19	cohorts	cohort	NNS
cord-353633-a4pu6rlu	207	20	,	,	,
cord-353633-a4pu6rlu	207	21	with	with	IN
cord-353633-a4pu6rlu	207	22	no	no	DT
cord-353633-a4pu6rlu	207	23	significant	significant	JJ
cord-353633-a4pu6rlu	207	24	changes	change	NNS
cord-353633-a4pu6rlu	207	25	being	be	VBG
cord-353633-a4pu6rlu	207	26	detected	detect	VBN
cord-353633-a4pu6rlu	207	27	[	[	-LRB-
cord-353633-a4pu6rlu	207	28	124	124	CD
cord-353633-a4pu6rlu	207	29	]	]	-RRB-
cord-353633-a4pu6rlu	207	30	.	.	.
cord-353633-a4pu6rlu	208	1	Future	future	JJ
cord-353633-a4pu6rlu	208	2	transcriptomic	transcriptomic	JJ
cord-353633-a4pu6rlu	208	3	modalities	modality	NNS
cord-353633-a4pu6rlu	208	4	should	should	MD
cord-353633-a4pu6rlu	208	5	approach	approach	VB
cord-353633-a4pu6rlu	208	6	all	all	DT
cord-353633-a4pu6rlu	208	7	different	different	JJ
cord-353633-a4pu6rlu	208	8	phases	phase	NNS
cord-353633-a4pu6rlu	208	9	and	and	CC
cord-353633-a4pu6rlu	208	10	components	component	NNS
cord-353633-a4pu6rlu	208	11	of	of	IN
cord-353633-a4pu6rlu	208	12	transcription	transcription	NN
cord-353633-a4pu6rlu	208	13	,	,	,
cord-353633-a4pu6rlu	208	14	kindle	kindle	NNP
cord-353633-a4pu6rlu	208	15	research	research	NN
cord-353633-a4pu6rlu	208	16	for	for	IN
cord-353633-a4pu6rlu	208	17	new	new	JJ
cord-353633-a4pu6rlu	208	18	remedies	remedy	NNS
cord-353633-a4pu6rlu	208	19	,	,	,
cord-353633-a4pu6rlu	208	20	and	and	CC
cord-353633-a4pu6rlu	208	21	investigate	investigate	VB
cord-353633-a4pu6rlu	208	22	the	the	DT
cord-353633-a4pu6rlu	208	23	associations	association	NNS
cord-353633-a4pu6rlu	208	24	of	of	IN
cord-353633-a4pu6rlu	208	25	liver	liver	NN
cord-353633-a4pu6rlu	208	26	disease	disease	NN
cord-353633-a4pu6rlu	208	27	with	with	IN
cord-353633-a4pu6rlu	208	28	various	various	JJ
cord-353633-a4pu6rlu	208	29	pathologies	pathology	NNS
cord-353633-a4pu6rlu	208	30	precipitated	precipitate	VBN
cord-353633-a4pu6rlu	208	31	by	by	IN
cord-353633-a4pu6rlu	208	32	its	-PRON-	PRP$
cord-353633-a4pu6rlu	208	33	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	208	34	milieu	milieu	NN
cord-353633-a4pu6rlu	208	35	.	.	.
cord-353633-a4pu6rlu	209	1	Transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	209	2	have	have	VBP
cord-353633-a4pu6rlu	209	3	been	be	VBN
cord-353633-a4pu6rlu	209	4	widely	widely	RB
cord-353633-a4pu6rlu	209	5	used	use	VBN
cord-353633-a4pu6rlu	209	6	and	and	CC
cord-353633-a4pu6rlu	209	7	have	have	VBP
cord-353633-a4pu6rlu	209	8	contributed	contribute	VBN
cord-353633-a4pu6rlu	209	9	significantly	significantly	RB
cord-353633-a4pu6rlu	209	10	to	to	IN
cord-353633-a4pu6rlu	209	11	our	-PRON-	PRP$
cord-353633-a4pu6rlu	209	12	understanding	understanding	NN
cord-353633-a4pu6rlu	209	13	of	of	IN
cord-353633-a4pu6rlu	209	14	the	the	DT
cord-353633-a4pu6rlu	209	15	pathophysiology	pathophysiology	NN
cord-353633-a4pu6rlu	209	16	of	of	IN
cord-353633-a4pu6rlu	209	17	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	209	18	.	.	.
cord-353633-a4pu6rlu	210	1	Transcriptomics	Transcriptomics	NNP
cord-353633-a4pu6rlu	210	2	,	,	,
cord-353633-a4pu6rlu	210	3	with	with	IN
cord-353633-a4pu6rlu	210	4	the	the	DT
cord-353633-a4pu6rlu	210	5	exception	exception	NN
cord-353633-a4pu6rlu	210	6	of	of	IN
cord-353633-a4pu6rlu	210	7	miRNAs	miRNAs	NNP
cord-353633-a4pu6rlu	210	8	,	,	,
cord-353633-a4pu6rlu	210	9	do	do	VB
cord-353633-a4pu6rlu	210	10	not	not	RB
cord-353633-a4pu6rlu	210	11	add	add	VB
cord-353633-a4pu6rlu	210	12	significant	significant	JJ
cord-353633-a4pu6rlu	210	13	value	value	NN
cord-353633-a4pu6rlu	210	14	in	in	IN
cord-353633-a4pu6rlu	210	15	non	non	JJ
cord-353633-a4pu6rlu	210	16	-	-	JJ
cord-353633-a4pu6rlu	210	17	invasive	invasive	JJ
cord-353633-a4pu6rlu	210	18	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	210	19	scores	score	NNS
cord-353633-a4pu6rlu	210	20	,	,	,
cord-353633-a4pu6rlu	210	21	since	since	IN
cord-353633-a4pu6rlu	210	22	their	-PRON-	PRP$
cord-353633-a4pu6rlu	210	23	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	210	24	profile	profile	NN
cord-353633-a4pu6rlu	210	25	is	be	VBZ
cord-353633-a4pu6rlu	210	26	not	not	RB
cord-353633-a4pu6rlu	210	27	adequately	adequately	RB
cord-353633-a4pu6rlu	210	28	reflected	reflect	VBN
cord-353633-a4pu6rlu	210	29	in	in	IN
cord-353633-a4pu6rlu	210	30	peripheral	peripheral	JJ
cord-353633-a4pu6rlu	210	31	blood	blood	NN
cord-353633-a4pu6rlu	210	32	.	.	.
cord-353633-a4pu6rlu	211	1	With	with	IN
cord-353633-a4pu6rlu	211	2	the	the	DT
cord-353633-a4pu6rlu	211	3	rapid	rapid	JJ
cord-353633-a4pu6rlu	211	4	improvement	improvement	NN
cord-353633-a4pu6rlu	211	5	of	of	IN
cord-353633-a4pu6rlu	211	6	available	available	JJ
cord-353633-a4pu6rlu	211	7	technologies	technology	NNS
cord-353633-a4pu6rlu	211	8	and	and	CC
cord-353633-a4pu6rlu	211	9	data	datum	NNS
cord-353633-a4pu6rlu	211	10	analysis	analysis	NN
cord-353633-a4pu6rlu	211	11	,	,	,
cord-353633-a4pu6rlu	211	12	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	211	13	are	be	VBP
cord-353633-a4pu6rlu	211	14	now	now	RB
cord-353633-a4pu6rlu	211	15	routinely	routinely	RB
cord-353633-a4pu6rlu	211	16	used	use	VBN
cord-353633-a4pu6rlu	211	17	in	in	IN
cord-353633-a4pu6rlu	211	18	order	order	NN
cord-353633-a4pu6rlu	211	19	to	to	TO
cord-353633-a4pu6rlu	211	20	identify	identify	VB
cord-353633-a4pu6rlu	211	21	potential	potential	JJ
cord-353633-a4pu6rlu	211	22	mechanistic	mechanistic	JJ
cord-353633-a4pu6rlu	211	23	pathways	pathway	NNS
cord-353633-a4pu6rlu	211	24	affected	affect	VBN
cord-353633-a4pu6rlu	211	25	by	by	IN
cord-353633-a4pu6rlu	211	26	drug	drug	NN
cord-353633-a4pu6rlu	211	27	candidates	candidate	NNS
cord-353633-a4pu6rlu	211	28	for	for	IN
cord-353633-a4pu6rlu	211	29	the	the	DT
cord-353633-a4pu6rlu	211	30	treatment	treatment	NN
cord-353633-a4pu6rlu	211	31	of	of	IN
cord-353633-a4pu6rlu	211	32	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	211	33	.	.	.
cord-353633-a4pu6rlu	212	1	Proteomics	Proteomics	NNP
cord-353633-a4pu6rlu	212	2	refers	refer	VBZ
cord-353633-a4pu6rlu	212	3	to	to	IN
cord-353633-a4pu6rlu	212	4	the	the	DT
cord-353633-a4pu6rlu	212	5	investigation	investigation	NN
cord-353633-a4pu6rlu	212	6	of	of	IN
cord-353633-a4pu6rlu	212	7	"	"	``
cord-353633-a4pu6rlu	212	8	proteome	proteome	NN
cord-353633-a4pu6rlu	212	9	"	"	''
cord-353633-a4pu6rlu	212	10	,	,	,
cord-353633-a4pu6rlu	212	11	thus	thus	RB
cord-353633-a4pu6rlu	212	12	to	to	IN
cord-353633-a4pu6rlu	212	13	all	all	DT
cord-353633-a4pu6rlu	212	14	proteins	protein	NNS
cord-353633-a4pu6rlu	212	15	expressed	express	VBN
cord-353633-a4pu6rlu	212	16	by	by	IN
cord-353633-a4pu6rlu	212	17	a	a	DT
cord-353633-a4pu6rlu	212	18	cell	cell	NN
cord-353633-a4pu6rlu	212	19	.	.	.
cord-353633-a4pu6rlu	213	1	The	the	DT
cord-353633-a4pu6rlu	213	2	proteome	proteome	NN
cord-353633-a4pu6rlu	213	3	,	,	,
cord-353633-a4pu6rlu	213	4	similar	similar	JJ
cord-353633-a4pu6rlu	213	5	to	to	IN
cord-353633-a4pu6rlu	213	6	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	213	7	and	and	CC
cord-353633-a4pu6rlu	213	8	epigenome	epigenome	NN
cord-353633-a4pu6rlu	213	9	,	,	,
cord-353633-a4pu6rlu	213	10	is	be	VBZ
cord-353633-a4pu6rlu	213	11	highly	highly	RB
cord-353633-a4pu6rlu	213	12	dynamic	dynamic	JJ
cord-353633-a4pu6rlu	213	13	.	.	.
cord-353633-a4pu6rlu	214	1	Cell	cell	NN
cord-353633-a4pu6rlu	214	2	activation	activation	NN
cord-353633-a4pu6rlu	214	3	,	,	,
cord-353633-a4pu6rlu	214	4	trafficking	trafficking	NN
cord-353633-a4pu6rlu	214	5	,	,	,
cord-353633-a4pu6rlu	214	6	differentiation	differentiation	NN
cord-353633-a4pu6rlu	214	7	or	or	CC
cord-353633-a4pu6rlu	214	8	transformation	transformation	NN
cord-353633-a4pu6rlu	214	9	as	as	RB
cord-353633-a4pu6rlu	214	10	well	well	RB
cord-353633-a4pu6rlu	214	11	as	as	IN
cord-353633-a4pu6rlu	214	12	tissue	tissue	NN
cord-353633-a4pu6rlu	214	13	type	type	NN
cord-353633-a4pu6rlu	214	14	have	have	VBP
cord-353633-a4pu6rlu	214	15	a	a	DT
cord-353633-a4pu6rlu	214	16	major	major	JJ
cord-353633-a4pu6rlu	214	17	impact	impact	NN
cord-353633-a4pu6rlu	214	18	on	on	IN
cord-353633-a4pu6rlu	214	19	the	the	DT
cord-353633-a4pu6rlu	214	20	proteome	proteome	NN
cord-353633-a4pu6rlu	214	21	.	.	.
cord-353633-a4pu6rlu	215	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	215	2	,	,	,
cord-353633-a4pu6rlu	215	3	posttranslational	posttranslational	JJ
cord-353633-a4pu6rlu	215	4	modifications	modification	NNS
cord-353633-a4pu6rlu	215	5	(	(	-LRB-
cord-353633-a4pu6rlu	215	6	phosphorylation	phosphorylation	NN
cord-353633-a4pu6rlu	215	7	,	,	,
cord-353633-a4pu6rlu	215	8	acetylation	acetylation	NN
cord-353633-a4pu6rlu	215	9	,	,	,
cord-353633-a4pu6rlu	215	10	methylation	methylation	NN
cord-353633-a4pu6rlu	215	11	,	,	,
cord-353633-a4pu6rlu	215	12	glycosylation	glycosylation	NN
cord-353633-a4pu6rlu	215	13	etc	etc	NN
cord-353633-a4pu6rlu	215	14	.	.	.
cord-353633-a4pu6rlu	215	15	)	)	-RRB-
cord-353633-a4pu6rlu	215	16	as	as	RB
cord-353633-a4pu6rlu	215	17	well	well	RB
cord-353633-a4pu6rlu	215	18	as	as	IN
cord-353633-a4pu6rlu	215	19	alternative	alternative	JJ
cord-353633-a4pu6rlu	215	20	splicing	splicing	NN
cord-353633-a4pu6rlu	215	21	render	render	NN
cord-353633-a4pu6rlu	215	22	proteome	proteome	NN
cord-353633-a4pu6rlu	215	23	much	much	RB
cord-353633-a4pu6rlu	215	24	more	more	JJR
cord-353633-a4pu6rlu	215	25	J	J	NNP
cord-353633-a4pu6rlu	215	26	o	o	NN
cord-353633-a4pu6rlu	215	27	u	u	NN
cord-353633-a4pu6rlu	215	28	r	r	NN
cord-353633-a4pu6rlu	215	29	n	n	NN
cord-353633-a4pu6rlu	215	30	a	a	DT
cord-353633-a4pu6rlu	215	31	l	l	NN
cord-353633-a4pu6rlu	215	32	P	p	NN
cord-353633-a4pu6rlu	215	33	r	r	NN
cord-353633-a4pu6rlu	215	34	e	e	NN
cord-353633-a4pu6rlu	215	35	-p	-p	NN
cord-353633-a4pu6rlu	215	36	r	r	NN
cord-353633-a4pu6rlu	215	37	o	o	NN
cord-353633-a4pu6rlu	216	1	o	o	UH
cord-353633-a4pu6rlu	216	2	f	f	NNP
cord-353633-a4pu6rlu	216	3	30	30	CD
cord-353633-a4pu6rlu	216	4	complex	complex	NN
cord-353633-a4pu6rlu	216	5	than	than	IN
cord-353633-a4pu6rlu	216	6	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	216	7	,	,	,
cord-353633-a4pu6rlu	216	8	with	with	IN
cord-353633-a4pu6rlu	216	9	more	more	JJR
cord-353633-a4pu6rlu	216	10	than	than	IN
cord-353633-a4pu6rlu	216	11	120,000	120,000	CD
cord-353633-a4pu6rlu	216	12	proteins	protein	NNS
cord-353633-a4pu6rlu	216	13	being	be	VBG
cord-353633-a4pu6rlu	216	14	expressed	express	VBN
cord-353633-a4pu6rlu	216	15	by	by	IN
cord-353633-a4pu6rlu	216	16	a	a	DT
cord-353633-a4pu6rlu	216	17	human	human	JJ
cord-353633-a4pu6rlu	216	18	cell	cell	NN
cord-353633-a4pu6rlu	216	19	.	.	.
cord-353633-a4pu6rlu	217	1	Finally	finally	RB
cord-353633-a4pu6rlu	217	2	,	,	,
cord-353633-a4pu6rlu	217	3	the	the	DT
cord-353633-a4pu6rlu	217	4	proteome	proteome	NN
cord-353633-a4pu6rlu	217	5	is	be	VBZ
cord-353633-a4pu6rlu	217	6	downstream	downstream	JJ
cord-353633-a4pu6rlu	217	7	of	of	IN
cord-353633-a4pu6rlu	217	8	genome	genome	NN
cord-353633-a4pu6rlu	217	9	and	and	CC
cord-353633-a4pu6rlu	217	10	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	217	11	,	,	,
cord-353633-a4pu6rlu	217	12	and	and	CC
cord-353633-a4pu6rlu	217	13	thus	thus	RB
cord-353633-a4pu6rlu	217	14	it	-PRON-	PRP
cord-353633-a4pu6rlu	217	15	is	be	VBZ
cord-353633-a4pu6rlu	217	16	stronger	strong	JJR
cord-353633-a4pu6rlu	217	17	associated	associate	VBN
cord-353633-a4pu6rlu	217	18	with	with	IN
cord-353633-a4pu6rlu	217	19	the	the	DT
cord-353633-a4pu6rlu	217	20	final	final	JJ
cord-353633-a4pu6rlu	217	21	phenotype	phenotype	NN
cord-353633-a4pu6rlu	217	22	[	[	-LRB-
cord-353633-a4pu6rlu	217	23	125	125	CD
cord-353633-a4pu6rlu	217	24	]	]	-RRB-
cord-353633-a4pu6rlu	217	25	.	.	.
cord-353633-a4pu6rlu	218	1	Proteomic	proteomic	NN
cord-353633-a4pu6rlu	218	2	analyses	analysis	NNS
cord-353633-a4pu6rlu	218	3	have	have	VBP
cord-353633-a4pu6rlu	218	4	been	be	VBN
cord-353633-a4pu6rlu	218	5	performed	perform	VBN
cord-353633-a4pu6rlu	218	6	for	for	IN
cord-353633-a4pu6rlu	218	7	cell	cell	NN
cord-353633-a4pu6rlu	218	8	line	line	NN
cord-353633-a4pu6rlu	218	9	-characterization	-characterization	NN
cord-353633-a4pu6rlu	218	10	or	or	CC
cord-353633-a4pu6rlu	218	11	for	for	IN
cord-353633-a4pu6rlu	218	12	protein	protein	NN
cord-353633-a4pu6rlu	218	13	investigation	investigation	NN
cord-353633-a4pu6rlu	218	14	and	and	CC
cord-353633-a4pu6rlu	218	15	identification	identification	NN
cord-353633-a4pu6rlu	218	16	in	in	IN
cord-353633-a4pu6rlu	218	17	tissues	tissue	NNS
cord-353633-a4pu6rlu	218	18	under	under	IN
cord-353633-a4pu6rlu	218	19	specific	specific	JJ
cord-353633-a4pu6rlu	218	20	conditions	condition	NNS
cord-353633-a4pu6rlu	218	21	or	or	CC
cord-353633-a4pu6rlu	218	22	treatments	treatment	NNS
cord-353633-a4pu6rlu	218	23	,	,	,
cord-353633-a4pu6rlu	218	24	but	but	CC
cord-353633-a4pu6rlu	218	25	their	-PRON-	PRP$
cord-353633-a4pu6rlu	218	26	use	use	NN
cord-353633-a4pu6rlu	218	27	has	have	VBZ
cord-353633-a4pu6rlu	218	28	been	be	VBN
cord-353633-a4pu6rlu	218	29	in	in	IN
cord-353633-a4pu6rlu	218	30	general	general	JJ
cord-353633-a4pu6rlu	218	31	rather	rather	RB
cord-353633-a4pu6rlu	218	32	limited	limited	JJ
cord-353633-a4pu6rlu	218	33	,	,	,
cord-353633-a4pu6rlu	218	34	especially	especially	RB
cord-353633-a4pu6rlu	218	35	for	for	IN
cord-353633-a4pu6rlu	218	36	biomarker	biomarker	NN
cord-353633-a4pu6rlu	218	37	or	or	CC
cord-353633-a4pu6rlu	218	38	drug	drug	NN
cord-353633-a4pu6rlu	218	39	discovery	discovery	NN
cord-353633-a4pu6rlu	218	40	[	[	-LRB-
cord-353633-a4pu6rlu	218	41	126	126	CD
cord-353633-a4pu6rlu	218	42	]	]	-RRB-
cord-353633-a4pu6rlu	218	43	.	.	.
cord-353633-a4pu6rlu	219	1	There	there	EX
cord-353633-a4pu6rlu	219	2	are	be	VBP
cord-353633-a4pu6rlu	219	3	several	several	JJ
cord-353633-a4pu6rlu	219	4	reasons	reason	NNS
cord-353633-a4pu6rlu	219	5	for	for	IN
cord-353633-a4pu6rlu	219	6	this	this	DT
cord-353633-a4pu6rlu	219	7	.	.	.
cord-353633-a4pu6rlu	220	1	First	first	RB
cord-353633-a4pu6rlu	220	2	,	,	,
cord-353633-a4pu6rlu	220	3	significant	significant	JJ
cord-353633-a4pu6rlu	220	4	technical	technical	JJ
cord-353633-a4pu6rlu	220	5	limitations	limitation	NNS
cord-353633-a4pu6rlu	220	6	exist	exist	VBP
cord-353633-a4pu6rlu	220	7	that	that	WDT
cord-353633-a4pu6rlu	220	8	restrict	restrict	VBP
cord-353633-a4pu6rlu	220	9	the	the	DT
cord-353633-a4pu6rlu	220	10	number	number	NN
cord-353633-a4pu6rlu	220	11	of	of	IN
cord-353633-a4pu6rlu	220	12	proteins	protein	NNS
cord-353633-a4pu6rlu	220	13	that	that	WDT
cord-353633-a4pu6rlu	220	14	can	can	MD
cord-353633-a4pu6rlu	220	15	be	be	VB
cord-353633-a4pu6rlu	220	16	detected	detect	VBN
cord-353633-a4pu6rlu	220	17	and	and	CC
cord-353633-a4pu6rlu	220	18	can	can	MD
cord-353633-a4pu6rlu	220	19	be	be	VB
cord-353633-a4pu6rlu	220	20	identified	identify	VBN
cord-353633-a4pu6rlu	220	21	with	with	IN
cord-353633-a4pu6rlu	220	22	certainty	certainty	NN
cord-353633-a4pu6rlu	220	23	.	.	.
cord-353633-a4pu6rlu	221	1	The	the	DT
cord-353633-a4pu6rlu	221	2	first	first	JJ
cord-353633-a4pu6rlu	221	3	efforts	effort	NNS
cord-353633-a4pu6rlu	221	4	involved	involve	VBD
cord-353633-a4pu6rlu	221	5	two	two	CD
cord-353633-a4pu6rlu	221	6	-	-	HYPH
cord-353633-a4pu6rlu	221	7	dimensional	dimensional	JJ
cord-353633-a4pu6rlu	221	8	gel	gel	NN
cord-353633-a4pu6rlu	221	9	electrophoresis	electrophoresis	NN
cord-353633-a4pu6rlu	221	10	and	and	CC
cord-353633-a4pu6rlu	221	11	were	be	VBD
cord-353633-a4pu6rlu	221	12	able	able	JJ
cord-353633-a4pu6rlu	221	13	to	to	TO
cord-353633-a4pu6rlu	221	14	detect	detect	VB
cord-353633-a4pu6rlu	221	15	some	some	DT
cord-353633-a4pu6rlu	221	16	few	few	JJ
cord-353633-a4pu6rlu	221	17	dozens	dozen	NNS
cord-353633-a4pu6rlu	221	18	of	of	IN
cord-353633-a4pu6rlu	221	19	spots	spot	NNS
cord-353633-a4pu6rlu	221	20	that	that	WDT
cord-353633-a4pu6rlu	221	21	were	be	VBD
cord-353633-a4pu6rlu	221	22	subsequently	subsequently	RB
cord-353633-a4pu6rlu	221	23	matched	match	VBN
cord-353633-a4pu6rlu	221	24	to	to	IN
cord-353633-a4pu6rlu	221	25	specific	specific	JJ
cord-353633-a4pu6rlu	221	26	proteins	protein	NNS
cord-353633-a4pu6rlu	221	27	with	with	IN
cord-353633-a4pu6rlu	221	28	the	the	DT
cord-353633-a4pu6rlu	221	29	use	use	NN
cord-353633-a4pu6rlu	221	30	of	of	IN
cord-353633-a4pu6rlu	221	31	MS	MS	NNP
cord-353633-a4pu6rlu	221	32	.	.	.
cord-353633-a4pu6rlu	222	1	Later	later	RB
cord-353633-a4pu6rlu	222	2	approaches	approach	NNS
cord-353633-a4pu6rlu	222	3	managed	manage	VBD
cord-353633-a4pu6rlu	222	4	to	to	TO
cord-353633-a4pu6rlu	222	5	detect	detect	VB
cord-353633-a4pu6rlu	222	6	more	more	JJR
cord-353633-a4pu6rlu	222	7	protein	protein	NN
cord-353633-a4pu6rlu	222	8	peaks	peak	NNS
cord-353633-a4pu6rlu	222	9	without	without	IN
cord-353633-a4pu6rlu	222	10	though	though	IN
cord-353633-a4pu6rlu	222	11	being	be	VBG
cord-353633-a4pu6rlu	222	12	able	able	JJ
cord-353633-a4pu6rlu	222	13	to	to	TO
cord-353633-a4pu6rlu	222	14	identify	identify	VB
cord-353633-a4pu6rlu	222	15	the	the	DT
cord-353633-a4pu6rlu	222	16	corresponding	correspond	VBG
cord-353633-a4pu6rlu	222	17	proteins	protein	NNS
cord-353633-a4pu6rlu	222	18	.	.	.
cord-353633-a4pu6rlu	223	1	Advances	advance	NNS
cord-353633-a4pu6rlu	223	2	in	in	IN
cord-353633-a4pu6rlu	223	3	methods	method	NNS
cord-353633-a4pu6rlu	223	4	have	have	VBP
cord-353633-a4pu6rlu	223	5	enabled	enable	VBN
cord-353633-a4pu6rlu	223	6	in	in	IN
cord-353633-a4pu6rlu	223	7	the	the	DT
cord-353633-a4pu6rlu	223	8	last	last	JJ
cord-353633-a4pu6rlu	223	9	years	year	NNS
cord-353633-a4pu6rlu	223	10	the	the	DT
cord-353633-a4pu6rlu	223	11	identification	identification	NN
cord-353633-a4pu6rlu	223	12	of	of	IN
cord-353633-a4pu6rlu	223	13	some	some	DT
cord-353633-a4pu6rlu	223	14	thousands	thousand	NNS
cord-353633-a4pu6rlu	223	15	of	of	IN
cord-353633-a4pu6rlu	223	16	proteins	protein	NNS
cord-353633-a4pu6rlu	223	17	but	but	CC
cord-353633-a4pu6rlu	223	18	still	still	RB
cord-353633-a4pu6rlu	223	19	the	the	DT
cord-353633-a4pu6rlu	223	20	largest	large	JJS
cord-353633-a4pu6rlu	223	21	part	part	NN
cord-353633-a4pu6rlu	223	22	of	of	IN
cord-353633-a4pu6rlu	223	23	proteome	proteome	NN
cord-353633-a4pu6rlu	223	24	can	can	MD
cord-353633-a4pu6rlu	223	25	not	not	RB
cord-353633-a4pu6rlu	223	26	be	be	VB
cord-353633-a4pu6rlu	223	27	investigated	investigate	VBN
cord-353633-a4pu6rlu	223	28	with	with	IN
cord-353633-a4pu6rlu	223	29	certainty	certainty	NN
cord-353633-a4pu6rlu	223	30	with	with	IN
cord-353633-a4pu6rlu	223	31	the	the	DT
cord-353633-a4pu6rlu	223	32	available	available	JJ
cord-353633-a4pu6rlu	223	33	technologies	technology	NNS
cord-353633-a4pu6rlu	223	34	.	.	.
cord-353633-a4pu6rlu	224	1	Second	second	JJ
cord-353633-a4pu6rlu	224	2	,	,	,
cord-353633-a4pu6rlu	224	3	reliable	reliable	JJ
cord-353633-a4pu6rlu	224	4	quantification	quantification	NN
cord-353633-a4pu6rlu	224	5	of	of	IN
cord-353633-a4pu6rlu	224	6	the	the	DT
cord-353633-a4pu6rlu	224	7	levels	level	NNS
cord-353633-a4pu6rlu	224	8	of	of	IN
cord-353633-a4pu6rlu	224	9	proteins	protein	NNS
cord-353633-a4pu6rlu	224	10	,	,	,
cord-353633-a4pu6rlu	224	11	especially	especially	RB
cord-353633-a4pu6rlu	224	12	in	in	IN
cord-353633-a4pu6rlu	224	13	blood	blood	NN
cord-353633-a4pu6rlu	224	14	has	have	VBZ
cord-353633-a4pu6rlu	224	15	been	be	VBN
cord-353633-a4pu6rlu	224	16	very	very	RB
cord-353633-a4pu6rlu	224	17	challenging	challenging	JJ
cord-353633-a4pu6rlu	224	18	.	.	.
cord-353633-a4pu6rlu	225	1	In	in	IN
cord-353633-a4pu6rlu	225	2	plasma	plasma	NN
cord-353633-a4pu6rlu	225	3	,	,	,
cord-353633-a4pu6rlu	225	4	three	three	CD
cord-353633-a4pu6rlu	225	5	classes	class	NNS
cord-353633-a4pu6rlu	225	6	of	of	IN
cord-353633-a4pu6rlu	225	7	proteins	protein	NNS
cord-353633-a4pu6rlu	225	8	mainly	mainly	RB
cord-353633-a4pu6rlu	225	9	exist	exist	VBP
cord-353633-a4pu6rlu	225	10	:	:	:
cord-353633-a4pu6rlu	225	11	a	a	LS
cord-353633-a4pu6rlu	225	12	)	)	-RRB-
cord-353633-a4pu6rlu	225	13	the	the	DT
cord-353633-a4pu6rlu	225	14	highly	highly	RB
cord-353633-a4pu6rlu	225	15	abundant	abundant	JJ
cord-353633-a4pu6rlu	225	16	proteins	protein	NNS
cord-353633-a4pu6rlu	225	17	,	,	,
cord-353633-a4pu6rlu	225	18	that	that	WDT
cord-353633-a4pu6rlu	225	19	include	include	VBP
cord-353633-a4pu6rlu	225	20	human	human	JJ
cord-353633-a4pu6rlu	225	21	serum	serum	NN
cord-353633-a4pu6rlu	225	22	albumin	albumin	NN
cord-353633-a4pu6rlu	225	23	(	(	-LRB-
cord-353633-a4pu6rlu	225	24	approximately	approximately	RB
cord-353633-a4pu6rlu	225	25	50	50	CD
cord-353633-a4pu6rlu	225	26	%	%	NN
cord-353633-a4pu6rlu	225	27	of	of	IN
cord-353633-a4pu6rlu	225	28	protein	protein	NN
cord-353633-a4pu6rlu	225	29	mass	mass	NN
cord-353633-a4pu6rlu	225	30	)	)	-RRB-
cord-353633-a4pu6rlu	225	31	,	,	,
cord-353633-a4pu6rlu	225	32	apolipoproteins	apolipoprotein	NNS
cord-353633-a4pu6rlu	225	33	,	,	,
cord-353633-a4pu6rlu	225	34	coagulation	coagulation	NN
cord-353633-a4pu6rlu	225	35	markers	marker	NNS
cord-353633-a4pu6rlu	225	36	and	and	CC
cord-353633-a4pu6rlu	225	37	acute	acute	JJ
cord-353633-a4pu6rlu	225	38	phase	phase	NN
cord-353633-a4pu6rlu	225	39	proteins	protein	NNS
cord-353633-a4pu6rlu	225	40	of	of	IN
cord-353633-a4pu6rlu	225	41	the	the	DT
cord-353633-a4pu6rlu	225	42	immune	immune	JJ
cord-353633-a4pu6rlu	225	43	system	system	NN
cord-353633-a4pu6rlu	225	44	,	,	,
cord-353633-a4pu6rlu	225	45	that	that	WDT
cord-353633-a4pu6rlu	225	46	are	be	VBP
cord-353633-a4pu6rlu	225	47	measured	measure	VBN
cord-353633-a4pu6rlu	225	48	in	in	IN
cord-353633-a4pu6rlu	225	49	mg	mg	NNP
cord-353633-a4pu6rlu	225	50	to	to	IN
cord-353633-a4pu6rlu	225	51	ug	ug	NNP
cord-353633-a4pu6rlu	225	52	/	/	SYM
cord-353633-a4pu6rlu	225	53	ml	ml	NN
cord-353633-a4pu6rlu	225	54	level	level	NN
cord-353633-a4pu6rlu	225	55	,	,	,
cord-353633-a4pu6rlu	225	56	b	b	LS
cord-353633-a4pu6rlu	225	57	)	)	-RRB-
cord-353633-a4pu6rlu	225	58	the	the	DT
cord-353633-a4pu6rlu	225	59	organ	organ	NN
cord-353633-a4pu6rlu	225	60	-	-	HYPH
cord-353633-a4pu6rlu	225	61	tissue	tissue	NN
cord-353633-a4pu6rlu	225	62	secreted	secrete	VBN
cord-353633-a4pu6rlu	225	63	proteins	protein	NNS
cord-353633-a4pu6rlu	225	64	without	without	IN
cord-353633-a4pu6rlu	225	65	functional	functional	JJ
cord-353633-a4pu6rlu	225	66	role	role	NN
cord-353633-a4pu6rlu	225	67	in	in	IN
cord-353633-a4pu6rlu	225	68	the	the	DT
cord-353633-a4pu6rlu	225	69	circulation	circulation	NN
cord-353633-a4pu6rlu	225	70	such	such	JJ
cord-353633-a4pu6rlu	225	71	as	as	IN
cord-353633-a4pu6rlu	225	72	ALT	ALT	NNP
cord-353633-a4pu6rlu	225	73	,	,	,
cord-353633-a4pu6rlu	225	74	AST	AST	NNP
cord-353633-a4pu6rlu	225	75	or	or	CC
cord-353633-a4pu6rlu	225	76	troponins	troponin	NNS
cord-353633-a4pu6rlu	225	77	,	,	,
cord-353633-a4pu6rlu	225	78	measured	measure	VBN
cord-353633-a4pu6rlu	225	79	in	in	IN
cord-353633-a4pu6rlu	225	80	ug	ug	NNP
cord-353633-a4pu6rlu	225	81	to	to	IN
cord-353633-a4pu6rlu	225	82	ng	ng	NNP
cord-353633-a4pu6rlu	225	83	/	/	SYM
cord-353633-a4pu6rlu	225	84	ml	ml	NNP
cord-353633-a4pu6rlu	225	85	,	,	,
cord-353633-a4pu6rlu	225	86	c	c	NN
cord-353633-a4pu6rlu	225	87	)	)	-RRB-
cord-353633-a4pu6rlu	226	1	the	the	DT
cord-353633-a4pu6rlu	226	2	signaling	signal	VBG
cord-353633-a4pu6rlu	226	3	molecules	molecule	NNS
cord-353633-a4pu6rlu	226	4	,	,	,
cord-353633-a4pu6rlu	226	5	such	such	JJ
cord-353633-a4pu6rlu	226	6	as	as	IN
cord-353633-a4pu6rlu	226	7	cytokines	cytokine	NNS
cord-353633-a4pu6rlu	226	8	or	or	CC
cord-353633-a4pu6rlu	226	9	insulin	insulin	NN
cord-353633-a4pu6rlu	226	10	,	,	,
cord-353633-a4pu6rlu	226	11	measured	measure	VBN
cord-353633-a4pu6rlu	226	12	at	at	IN
cord-353633-a4pu6rlu	226	13	ng	ng	NNP
cord-353633-a4pu6rlu	227	1	to	to	IN
cord-353633-a4pu6rlu	227	2	pg	pg	NNP
cord-353633-a4pu6rlu	227	3	/	/	SYM
cord-353633-a4pu6rlu	227	4	ml	ml	NN
cord-353633-a4pu6rlu	227	5	level	level	NN
cord-353633-a4pu6rlu	227	6	.	.	.
cord-353633-a4pu6rlu	228	1	This	this	DT
cord-353633-a4pu6rlu	228	2	extreme	extreme	JJ
cord-353633-a4pu6rlu	228	3	range	range	NN
cord-353633-a4pu6rlu	228	4	While	while	IN
cord-353633-a4pu6rlu	228	5	keeping	keep	VBG
cord-353633-a4pu6rlu	228	6	in	in	IN
cord-353633-a4pu6rlu	228	7	mind	mind	NN
cord-353633-a4pu6rlu	228	8	the	the	DT
cord-353633-a4pu6rlu	228	9	above	above	JJ
cord-353633-a4pu6rlu	228	10	limitations	limitation	NNS
cord-353633-a4pu6rlu	228	11	,	,	,
cord-353633-a4pu6rlu	228	12	we	-PRON-	PRP
cord-353633-a4pu6rlu	228	13	next	next	RB
cord-353633-a4pu6rlu	228	14	present	present	VBP
cord-353633-a4pu6rlu	228	15	the	the	DT
cord-353633-a4pu6rlu	228	16	efforts	effort	NNS
cord-353633-a4pu6rlu	228	17	to	to	TO
cord-353633-a4pu6rlu	228	18	identify	identify	VB
cord-353633-a4pu6rlu	228	19	pathophysiological	pathophysiological	JJ
cord-353633-a4pu6rlu	228	20	pathways	pathway	NNS
cord-353633-a4pu6rlu	228	21	and	and	CC
cord-353633-a4pu6rlu	228	22	develop	develop	VB
cord-353633-a4pu6rlu	228	23	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	228	24	models	model	NNS
cord-353633-a4pu6rlu	228	25	for	for	IN
cord-353633-a4pu6rlu	228	26	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	228	27	with	with	IN
cord-353633-a4pu6rlu	228	28	the	the	DT
cord-353633-a4pu6rlu	228	29	use	use	NN
cord-353633-a4pu6rlu	228	30	of	of	IN
cord-353633-a4pu6rlu	228	31	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	228	32	.	.	.
cord-353633-a4pu6rlu	229	1	Several	several	JJ
cord-353633-a4pu6rlu	229	2	studies	study	NNS
cord-353633-a4pu6rlu	229	3	have	have	VBP
cord-353633-a4pu6rlu	229	4	investigated	investigate	VBN
cord-353633-a4pu6rlu	229	5	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	229	6	proteome	proteome	NN
cord-353633-a4pu6rlu	229	7	alone	alone	RB
cord-353633-a4pu6rlu	229	8	or	or	CC
cord-353633-a4pu6rlu	229	9	in	in	IN
cord-353633-a4pu6rlu	229	10	combination	combination	NN
cord-353633-a4pu6rlu	229	11	with	with	IN
cord-353633-a4pu6rlu	229	12	blood	blood	NN
cord-353633-a4pu6rlu	229	13	proteome	proteome	NN
cord-353633-a4pu6rlu	229	14	,	,	,
cord-353633-a4pu6rlu	229	15	either	either	CC
cord-353633-a4pu6rlu	229	16	in	in	IN
cord-353633-a4pu6rlu	229	17	animal	animal	NN
cord-353633-a4pu6rlu	229	18	models	model	NNS
cord-353633-a4pu6rlu	229	19	or	or	CC
cord-353633-a4pu6rlu	229	20	in	in	IN
cord-353633-a4pu6rlu	229	21	humans	human	NNS
cord-353633-a4pu6rlu	229	22	with	with	IN
cord-353633-a4pu6rlu	229	23	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	229	24	,	,	,
cord-353633-a4pu6rlu	229	25	aiming	aim	VBG
cord-353633-a4pu6rlu	229	26	to	to	TO
cord-353633-a4pu6rlu	229	27	answer	answer	VB
cord-353633-a4pu6rlu	229	28	fundamental	fundamental	JJ
cord-353633-a4pu6rlu	229	29	pathophysiological	pathophysiological	JJ
cord-353633-a4pu6rlu	229	30	questions	question	NNS
cord-353633-a4pu6rlu	229	31	[	[	-LRB-
cord-353633-a4pu6rlu	229	32	127	127	CD
cord-353633-a4pu6rlu	229	33	]	]	-RRB-
cord-353633-a4pu6rlu	229	34	[	[	-LRB-
cord-353633-a4pu6rlu	229	35	128	128	CD
cord-353633-a4pu6rlu	229	36	]	]	-RRB-
cord-353633-a4pu6rlu	229	37	[	[	-LRB-
cord-353633-a4pu6rlu	229	38	129	129	CD
cord-353633-a4pu6rlu	229	39	]	]	-RRB-
cord-353633-a4pu6rlu	229	40	.	.	.
cord-353633-a4pu6rlu	230	1	In	in	IN
cord-353633-a4pu6rlu	230	2	one	one	CD
cord-353633-a4pu6rlu	230	3	recent	recent	JJ
cord-353633-a4pu6rlu	230	4	study	study	NN
cord-353633-a4pu6rlu	230	5	,	,	,
cord-353633-a4pu6rlu	230	6	the	the	DT
cord-353633-a4pu6rlu	230	7	levels	level	NNS
cord-353633-a4pu6rlu	230	8	and	and	CC
cord-353633-a4pu6rlu	230	9	cellular	cellular	JJ
cord-353633-a4pu6rlu	230	10	distributions	distribution	NNS
cord-353633-a4pu6rlu	230	11	of	of	IN
cord-353633-a4pu6rlu	230	12	6,000	6,000	CD
cord-353633-a4pu6rlu	230	13	liver	liver	NN
cord-353633-a4pu6rlu	230	14	proteins	protein	NNS
cord-353633-a4pu6rlu	230	15	and	and	CC
cord-353633-a4pu6rlu	230	16	16,000	16,000	CD
cord-353633-a4pu6rlu	230	17	phosphopeptides	phosphopeptide	NNS
cord-353633-a4pu6rlu	230	18	have	have	VBP
cord-353633-a4pu6rlu	230	19	been	be	VBN
cord-353633-a4pu6rlu	230	20	assessed	assess	VBN
cord-353633-a4pu6rlu	230	21	in	in	IN
cord-353633-a4pu6rlu	230	22	the	the	DT
cord-353633-a4pu6rlu	230	23	liver	liver	NN
cord-353633-a4pu6rlu	230	24	of	of	IN
cord-353633-a4pu6rlu	230	25	mice	mouse	NNS
cord-353633-a4pu6rlu	230	26	developing	develop	VBG
cord-353633-a4pu6rlu	230	27	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	230	28	steatosis	steatosis	NN
cord-353633-a4pu6rlu	230	29	due	due	IN
cord-353633-a4pu6rlu	230	30	to	to	IN
cord-353633-a4pu6rlu	230	31	high	high	JJ
cord-353633-a4pu6rlu	230	32	fat	fat	NN
cord-353633-a4pu6rlu	230	33	diet	diet	NN
cord-353633-a4pu6rlu	230	34	(	(	-LRB-
cord-353633-a4pu6rlu	230	35	HFD	HFD	NNP
cord-353633-a4pu6rlu	230	36	)	)	-RRB-
cord-353633-a4pu6rlu	230	37	.	.	.
cord-353633-a4pu6rlu	231	1	This	this	DT
cord-353633-a4pu6rlu	231	2	provided	provide	VBD
cord-353633-a4pu6rlu	231	3	important	important	JJ
cord-353633-a4pu6rlu	231	4	J	J	NNP
cord-353633-a4pu6rlu	231	5	o	o	NN
cord-353633-a4pu6rlu	231	6	u	u	NN
cord-353633-a4pu6rlu	231	7	r	r	NN
cord-353633-a4pu6rlu	231	8	n	n	NN
cord-353633-a4pu6rlu	231	9	a	a	DT
cord-353633-a4pu6rlu	231	10	l	l	NN
cord-353633-a4pu6rlu	231	11	P	p	NN
cord-353633-a4pu6rlu	231	12	r	r	NN
cord-353633-a4pu6rlu	231	13	e	e	NN
cord-353633-a4pu6rlu	231	14	-p	-p	NN
cord-353633-a4pu6rlu	231	15	r	r	NN
cord-353633-a4pu6rlu	231	16	o	o	NN
cord-353633-a4pu6rlu	231	17	o	o	NN
cord-353633-a4pu6rlu	231	18	f	f	NN
cord-353633-a4pu6rlu	231	19	32	32	CD
cord-353633-a4pu6rlu	231	20	fundamental	fundamental	JJ
cord-353633-a4pu6rlu	231	21	information	information	NN
cord-353633-a4pu6rlu	231	22	about	about	IN
cord-353633-a4pu6rlu	231	23	the	the	DT
cord-353633-a4pu6rlu	231	24	reorganization	reorganization	NN
cord-353633-a4pu6rlu	231	25	of	of	IN
cord-353633-a4pu6rlu	231	26	organelles	organelle	NNS
cord-353633-a4pu6rlu	231	27	,	,	,
cord-353633-a4pu6rlu	231	28	lipid	lipid	NN
cord-353633-a4pu6rlu	231	29	accumulation	accumulation	NN
cord-353633-a4pu6rlu	231	30	and	and	CC
cord-353633-a4pu6rlu	231	31	cellular	cellular	JJ
cord-353633-a4pu6rlu	231	32	dysfunction	dysfunction	NN
cord-353633-a4pu6rlu	231	33	that	that	WDT
cord-353633-a4pu6rlu	231	34	occurs	occur	VBZ
cord-353633-a4pu6rlu	231	35	with	with	IN
cord-353633-a4pu6rlu	231	36	nutrient	nutrient	NN
cord-353633-a4pu6rlu	231	37	overload	overload	NN
cord-353633-a4pu6rlu	231	38	[	[	-LRB-
cord-353633-a4pu6rlu	231	39	129	129	CD
cord-353633-a4pu6rlu	231	40	]	]	-RRB-
cord-353633-a4pu6rlu	231	41	.	.	.
cord-353633-a4pu6rlu	232	1	In	in	IN
cord-353633-a4pu6rlu	232	2	another	another	DT
cord-353633-a4pu6rlu	232	3	study	study	NN
cord-353633-a4pu6rlu	232	4	,	,	,
cord-353633-a4pu6rlu	232	5	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	232	6	in	in	IN
cord-353633-a4pu6rlu	232	7	liver	liver	NN
cord-353633-a4pu6rlu	232	8	biopsies	biopsy	NNS
cord-353633-a4pu6rlu	232	9	identified	identify	VBD
cord-353633-a4pu6rlu	232	10	almost	almost	RB
cord-353633-a4pu6rlu	232	11	220	220	CD
cord-353633-a4pu6rlu	232	12	proteins	protein	NNS
cord-353633-a4pu6rlu	232	13	that	that	IN
cord-353633-a4pu6rlu	232	14	their	-PRON-	PRP$
cord-353633-a4pu6rlu	232	15	levels	level	NNS
cord-353633-a4pu6rlu	232	16	significantly	significantly	RB
cord-353633-a4pu6rlu	232	17	differ	differ	VBP
cord-353633-a4pu6rlu	232	18	in	in	IN
cord-353633-a4pu6rlu	232	19	patients	patient	NNS
cord-353633-a4pu6rlu	232	20	with	with	IN
cord-353633-a4pu6rlu	232	21	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	232	22	compared	compare	VBN
cord-353633-a4pu6rlu	232	23	to	to	IN
cord-353633-a4pu6rlu	232	24	obese	obese	JJ
cord-353633-a4pu6rlu	232	25	metabolically	metabolically	RB
cord-353633-a4pu6rlu	232	26	healthy	healthy	JJ
cord-353633-a4pu6rlu	232	27	individuals	individual	NNS
cord-353633-a4pu6rlu	232	28	.	.	.
cord-353633-a4pu6rlu	233	1	The	the	DT
cord-353633-a4pu6rlu	233	2	proteins	protein	NNS
cord-353633-a4pu6rlu	233	3	that	that	WDT
cord-353633-a4pu6rlu	233	4	their	-PRON-	PRP$
cord-353633-a4pu6rlu	233	5	levels	level	NNS
cord-353633-a4pu6rlu	233	6	were	be	VBD
cord-353633-a4pu6rlu	233	7	increased	increase	VBN
cord-353633-a4pu6rlu	233	8	in	in	IN
cord-353633-a4pu6rlu	233	9	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	233	10	were	be	VBD
cord-353633-a4pu6rlu	233	11	involved	involve	VBN
cord-353633-a4pu6rlu	233	12	in	in	IN
cord-353633-a4pu6rlu	233	13	PPAR	PPAR	NNP
cord-353633-a4pu6rlu	233	14	-	-	HYPH
cord-353633-a4pu6rlu	233	15	signaling	signal	VBG
cord-353633-a4pu6rlu	233	16	and	and	CC
cord-353633-a4pu6rlu	233	17	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	233	18	matrix	matrix	NN
cord-353633-a4pu6rlu	233	19	-	-	HYPH
cord-353633-a4pu6rlu	233	20	receptor	receptor	NN
cord-353633-a4pu6rlu	233	21	interactions	interaction	NNS
cord-353633-a4pu6rlu	233	22	whereas	whereas	IN
cord-353633-a4pu6rlu	233	23	the	the	DT
cord-353633-a4pu6rlu	233	24	ones	one	NNS
cord-353633-a4pu6rlu	233	25	that	that	WDT
cord-353633-a4pu6rlu	233	26	their	-PRON-	PRP$
cord-353633-a4pu6rlu	233	27	levels	level	NNS
cord-353633-a4pu6rlu	233	28	were	be	VBD
cord-353633-a4pu6rlu	233	29	reduced	reduce	VBN
cord-353633-a4pu6rlu	233	30	,	,	,
cord-353633-a4pu6rlu	233	31	were	be	VBD
cord-353633-a4pu6rlu	233	32	mainly	mainly	RB
cord-353633-a4pu6rlu	233	33	localized	localize	VBN
cord-353633-a4pu6rlu	233	34	in	in	IN
cord-353633-a4pu6rlu	233	35	mitochondria	mitochondrion	NNS
cord-353633-a4pu6rlu	233	36	and	and	CC
cord-353633-a4pu6rlu	233	37	participated	participate	VBD
cord-353633-a4pu6rlu	233	38	in	in	IN
cord-353633-a4pu6rlu	233	39	oxidative	oxidative	JJ
cord-353633-a4pu6rlu	233	40	phosphorylation	phosphorylation	NN
cord-353633-a4pu6rlu	233	41	[	[	-LRB-
cord-353633-a4pu6rlu	233	42	128	128	CD
cord-353633-a4pu6rlu	233	43	]	]	-RRB-
cord-353633-a4pu6rlu	233	44	.	.	.
cord-353633-a4pu6rlu	234	1	In	in	IN
cord-353633-a4pu6rlu	234	2	a	a	DT
cord-353633-a4pu6rlu	234	3	combined	combined	JJ
cord-353633-a4pu6rlu	234	4	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	234	5	phosphoproteome	phosphoproteome	NN
cord-353633-a4pu6rlu	234	6	and	and	CC
cord-353633-a4pu6rlu	234	7	serum	serum	NN
cord-353633-a4pu6rlu	234	8	proteome	proteome	NN
cord-353633-a4pu6rlu	234	9	analysis	analysis	NN
cord-353633-a4pu6rlu	234	10	of	of	IN
cord-353633-a4pu6rlu	234	11	67	67	CD
cord-353633-a4pu6rlu	234	12	biopsy	biopsy	NN
cord-353633-a4pu6rlu	234	13	-	-	HYPH
cord-353633-a4pu6rlu	234	14	proven	prove	VBN
cord-353633-a4pu6rlu	234	15	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	234	16	subjects	subject	NNS
cord-353633-a4pu6rlu	234	17	,	,	,
cord-353633-a4pu6rlu	234	18	the	the	DT
cord-353633-a4pu6rlu	234	19	ASK1-MAPK	ask1-mapk	CD
cord-353633-a4pu6rlu	234	20	pathway	pathway	NN
cord-353633-a4pu6rlu	234	21	that	that	WDT
cord-353633-a4pu6rlu	234	22	is	be	VBZ
cord-353633-a4pu6rlu	234	23	activated	activate	VBN
cord-353633-a4pu6rlu	234	24	by	by	IN
cord-353633-a4pu6rlu	234	25	IL-10	IL-10	NNP
cord-353633-a4pu6rlu	234	26	was	be	VBD
cord-353633-a4pu6rlu	234	27	recognized	recognize	VBN
cord-353633-a4pu6rlu	234	28	as	as	IN
cord-353633-a4pu6rlu	234	29	important	important	JJ
cord-353633-a4pu6rlu	234	30	for	for	IN
cord-353633-a4pu6rlu	234	31	liver	liver	NN
cord-353633-a4pu6rlu	234	32	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	234	33	,	,	,
cord-353633-a4pu6rlu	234	34	indicated	indicate	VBN
cord-353633-a4pu6rlu	234	35	by	by	IN
cord-353633-a4pu6rlu	234	36	its	-PRON-	PRP$
cord-353633-a4pu6rlu	234	37	strong	strong	JJ
cord-353633-a4pu6rlu	234	38	association	association	NN
cord-353633-a4pu6rlu	234	39	with	with	IN
cord-353633-a4pu6rlu	234	40	higher	high	JJR
cord-353633-a4pu6rlu	234	41	%	%	NN
cord-353633-a4pu6rlu	234	42	of	of	IN
cord-353633-a4pu6rlu	234	43	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	234	44	collagen	collagen	NN
cord-353633-a4pu6rlu	234	45	.	.	.
cord-353633-a4pu6rlu	235	1	In	in	IN
cord-353633-a4pu6rlu	235	2	serum	serum	NN
cord-353633-a4pu6rlu	235	3	,	,	,
cord-353633-a4pu6rlu	235	4	alpha-2	alpha-2	NN
cord-353633-a4pu6rlu	235	5	macroglobulin	macroglobulin	NN
cord-353633-a4pu6rlu	235	6	and	and	CC
cord-353633-a4pu6rlu	235	7	coagulation	coagulation	NN
cord-353633-a4pu6rlu	235	8	factor	factor	NN
cord-353633-a4pu6rlu	236	1	V	V	NNP
cord-353633-a4pu6rlu	236	2	were	be	VBD
cord-353633-a4pu6rlu	236	3	strongly	strongly	RB
cord-353633-a4pu6rlu	236	4	associated	associate	VBN
cord-353633-a4pu6rlu	236	5	with	with	IN
cord-353633-a4pu6rlu	236	6	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	236	7	collagen	collagen	NN
cord-353633-a4pu6rlu	236	8	[	[	-LRB-
cord-353633-a4pu6rlu	236	9	127	127	CD
cord-353633-a4pu6rlu	236	10	]	]	-RRB-
cord-353633-a4pu6rlu	236	11	.	.	.
cord-353633-a4pu6rlu	237	1	It	-PRON-	PRP
cord-353633-a4pu6rlu	237	2	has	have	VBZ
cord-353633-a4pu6rlu	237	3	thus	thus	RB
cord-353633-a4pu6rlu	237	4	been	be	VBN
cord-353633-a4pu6rlu	237	5	suggested	suggest	VBN
cord-353633-a4pu6rlu	237	6	that	that	IN
cord-353633-a4pu6rlu	237	7	these	these	DT
cord-353633-a4pu6rlu	237	8	pathways	pathway	NNS
cord-353633-a4pu6rlu	237	9	can	can	MD
cord-353633-a4pu6rlu	237	10	potentially	potentially	RB
cord-353633-a4pu6rlu	237	11	serve	serve	VB
cord-353633-a4pu6rlu	237	12	as	as	IN
cord-353633-a4pu6rlu	237	13	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	237	14	targets	target	NNS
cord-353633-a4pu6rlu	237	15	.	.	.
cord-353633-a4pu6rlu	238	1	In	in	IN
cord-353633-a4pu6rlu	238	2	another	another	DT
cord-353633-a4pu6rlu	238	3	approach	approach	NN
cord-353633-a4pu6rlu	238	4	,	,	,
cord-353633-a4pu6rlu	238	5	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	238	6	differences	difference	NNS
cord-353633-a4pu6rlu	238	7	in	in	IN
cord-353633-a4pu6rlu	238	8	liver	liver	NN
cord-353633-a4pu6rlu	238	9	tissues	tissue	NNS
cord-353633-a4pu6rlu	238	10	of	of	IN
cord-353633-a4pu6rlu	238	11	obese	obese	JJ
cord-353633-a4pu6rlu	238	12	patients	patient	NNS
cord-353633-a4pu6rlu	238	13	with	with	IN
cord-353633-a4pu6rlu	238	14	vs	vs	NN
cord-353633-a4pu6rlu	238	15	without	without	IN
cord-353633-a4pu6rlu	238	16	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	238	17	were	be	VBD
cord-353633-a4pu6rlu	238	18	investigated	investigate	VBN
cord-353633-a4pu6rlu	238	19	.	.	.
cord-353633-a4pu6rlu	239	1	The	the	DT
cord-353633-a4pu6rlu	239	2	analysis	analysis	NN
cord-353633-a4pu6rlu	239	3	identified	identify	VBD
cord-353633-a4pu6rlu	239	4	850	850	CD
cord-353633-a4pu6rlu	239	5	proteins	protein	NNS
cord-353633-a4pu6rlu	239	6	,	,	,
cord-353633-a4pu6rlu	239	7	from	from	IN
cord-353633-a4pu6rlu	239	8	which	which	WDT
cord-353633-a4pu6rlu	239	9	27	27	CD
cord-353633-a4pu6rlu	239	10	were	be	VBD
cord-353633-a4pu6rlu	239	11	significantly	significantly	RB
cord-353633-a4pu6rlu	239	12	different	different	JJ
cord-353633-a4pu6rlu	239	13	between	between	IN
cord-353633-a4pu6rlu	239	14	the	the	DT
cord-353633-a4pu6rlu	239	15	two	two	CD
cord-353633-a4pu6rlu	239	16	groups	group	NNS
cord-353633-a4pu6rlu	239	17	.	.	.
cord-353633-a4pu6rlu	240	1	Levels	level	NNS
cord-353633-a4pu6rlu	240	2	of	of	IN
cord-353633-a4pu6rlu	240	3	proteins	protein	NNS
cord-353633-a4pu6rlu	240	4	involved	involve	VBN
cord-353633-a4pu6rlu	240	5	in	in	IN
cord-353633-a4pu6rlu	240	6	methionine	methionine	NN
cord-353633-a4pu6rlu	240	7	metabolism	metabolism	NN
cord-353633-a4pu6rlu	240	8	and	and	CC
cord-353633-a4pu6rlu	240	9	especially	especially	RB
cord-353633-a4pu6rlu	240	10	of	of	IN
cord-353633-a4pu6rlu	240	11	glutathione	glutathione	NN
cord-353633-a4pu6rlu	240	12	were	be	VBD
cord-353633-a4pu6rlu	240	13	reduced	reduce	VBN
cord-353633-a4pu6rlu	240	14	whereas	whereas	IN
cord-353633-a4pu6rlu	240	15	levels	level	NNS
cord-353633-a4pu6rlu	240	16	of	of	IN
cord-353633-a4pu6rlu	240	17	other	other	JJ
cord-353633-a4pu6rlu	240	18	proteins	protein	NNS
cord-353633-a4pu6rlu	240	19	involved	involve	VBN
cord-353633-a4pu6rlu	240	20	in	in	IN
cord-353633-a4pu6rlu	240	21	oxidative	oxidative	JJ
cord-353633-a4pu6rlu	240	22	stress	stress	NN
cord-353633-a4pu6rlu	240	23	were	be	VBD
cord-353633-a4pu6rlu	240	24	increased	increase	VBN
cord-353633-a4pu6rlu	240	25	in	in	IN
cord-353633-a4pu6rlu	240	26	the	the	DT
cord-353633-a4pu6rlu	240	27	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	240	28	group	group	NN
cord-353633-a4pu6rlu	240	29	[	[	-LRB-
cord-353633-a4pu6rlu	240	30	130	130	CD
cord-353633-a4pu6rlu	240	31	]	]	-RRB-
cord-353633-a4pu6rlu	240	32	.	.	.
cord-353633-a4pu6rlu	241	1	Expanding	expand	VBG
cord-353633-a4pu6rlu	241	2	on	on	IN
cord-353633-a4pu6rlu	241	3	complications	complication	NNS
cord-353633-a4pu6rlu	241	4	of	of	IN
cord-353633-a4pu6rlu	241	5	the	the	DT
cord-353633-a4pu6rlu	241	6	disease	disease	NN
cord-353633-a4pu6rlu	241	7	,	,	,
cord-353633-a4pu6rlu	241	8	the	the	DT
cord-353633-a4pu6rlu	241	9	proteome	proteome	NN
cord-353633-a4pu6rlu	241	10	of	of	IN
cord-353633-a4pu6rlu	241	11	liver	liver	NN
cord-353633-a4pu6rlu	241	12	tissues	tissue	NNS
cord-353633-a4pu6rlu	241	13	with	with	IN
cord-353633-a4pu6rlu	241	14	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	241	15	from	from	IN
cord-353633-a4pu6rlu	241	16	mice	mouse	NNS
cord-353633-a4pu6rlu	241	17	developing	develop	VBG
cord-353633-a4pu6rlu	241	18	HCC	HCC	NNP
cord-353633-a4pu6rlu	241	19	has	have	VBZ
cord-353633-a4pu6rlu	241	20	been	be	VBN
cord-353633-a4pu6rlu	241	21	assessed	assess	VBN
cord-353633-a4pu6rlu	241	22	.	.	.
cord-353633-a4pu6rlu	242	1	Differences	difference	NNS
cord-353633-a4pu6rlu	242	2	in	in	IN
cord-353633-a4pu6rlu	242	3	tumor	tumor	NN
cord-353633-a4pu6rlu	242	4	suppressor	suppressor	NN
cord-353633-a4pu6rlu	242	5	genes	gene	NNS
cord-353633-a4pu6rlu	242	6	and	and	CC
cord-353633-a4pu6rlu	242	7	oncogenes	oncogene	NNS
cord-353633-a4pu6rlu	242	8	were	be	VBD
cord-353633-a4pu6rlu	242	9	observed	observe	VBN
cord-353633-a4pu6rlu	242	10	,	,	,
cord-353633-a4pu6rlu	242	11	which	which	WDT
cord-353633-a4pu6rlu	242	12	were	be	VBD
cord-353633-a4pu6rlu	242	13	further	further	RB
cord-353633-a4pu6rlu	242	14	investigated	investigate	VBN
cord-353633-a4pu6rlu	242	15	in	in	IN
cord-353633-a4pu6rlu	242	16	human	human	JJ
cord-353633-a4pu6rlu	242	17	samples	sample	NNS
cord-353633-a4pu6rlu	242	18	with	with	IN
cord-353633-a4pu6rlu	242	19	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	242	20	and	and	CC
cord-353633-a4pu6rlu	242	21	HCC	HCC	NNP
cord-353633-a4pu6rlu	242	22	.	.	.
cord-353633-a4pu6rlu	243	1	Among	among	IN
cord-353633-a4pu6rlu	243	2	them	-PRON-	PRP
cord-353633-a4pu6rlu	243	3	S100A11	s100a11	NN
cord-353633-a4pu6rlu	243	4	,	,	,
cord-353633-a4pu6rlu	243	5	which	which	WDT
cord-353633-a4pu6rlu	243	6	is	be	VBZ
cord-353633-a4pu6rlu	243	7	secreted	secrete	VBN
cord-353633-a4pu6rlu	243	8	by	by	IN
cord-353633-a4pu6rlu	243	9	cancer	cancer	NN
cord-353633-a4pu6rlu	243	10	cells	cell	NNS
cord-353633-a4pu6rlu	243	11	and	and	CC
cord-353633-a4pu6rlu	243	12	stimulates	stimulate	VBZ
cord-353633-a4pu6rlu	243	13	cell	cell	NN
cord-353633-a4pu6rlu	243	14	J	J	NNP
cord-353633-a4pu6rlu	243	15	o	o	NN
cord-353633-a4pu6rlu	243	16	u	u	NN
cord-353633-a4pu6rlu	243	17	r	r	NN
cord-353633-a4pu6rlu	243	18	n	n	NN
cord-353633-a4pu6rlu	243	19	a	a	DT
cord-353633-a4pu6rlu	243	20	l	l	NN
cord-353633-a4pu6rlu	243	21	P	p	NN
cord-353633-a4pu6rlu	243	22	r	r	NN
cord-353633-a4pu6rlu	243	23	e	e	NN
cord-353633-a4pu6rlu	244	1	-p	-p	:
cord-353633-a4pu6rlu	245	1	r	r	NN
cord-353633-a4pu6rlu	245	2	o	o	NN
cord-353633-a4pu6rlu	245	3	o	o	NN
cord-353633-a4pu6rlu	245	4	f	f	NN
cord-353633-a4pu6rlu	245	5	33	33	CD
cord-353633-a4pu6rlu	245	6	proliferation	proliferation	NN
cord-353633-a4pu6rlu	245	7	and	and	CC
cord-353633-a4pu6rlu	245	8	migration	migration	NN
cord-353633-a4pu6rlu	245	9	,	,	,
cord-353633-a4pu6rlu	245	10	was	be	VBD
cord-353633-a4pu6rlu	245	11	identified	identify	VBN
cord-353633-a4pu6rlu	245	12	and	and	CC
cord-353633-a4pu6rlu	245	13	associated	associate	VBN
cord-353633-a4pu6rlu	245	14	with	with	IN
cord-353633-a4pu6rlu	245	15	high	high	JJ
cord-353633-a4pu6rlu	245	16	-	-	HYPH
cord-353633-a4pu6rlu	245	17	grade	grade	NN
cord-353633-a4pu6rlu	245	18	HCC	HCC	NNP
cord-353633-a4pu6rlu	245	19	and	and	CC
cord-353633-a4pu6rlu	245	20	poor	poor	JJ
cord-353633-a4pu6rlu	245	21	prognosis	prognosis	NN
cord-353633-a4pu6rlu	245	22	[	[	-LRB-
cord-353633-a4pu6rlu	245	23	128	128	CD
cord-353633-a4pu6rlu	245	24	]	]	-RRB-
cord-353633-a4pu6rlu	245	25	.	.	.
cord-353633-a4pu6rlu	246	1	A	a	DT
cord-353633-a4pu6rlu	246	2	small	small	JJ
cord-353633-a4pu6rlu	246	3	number	number	NN
cord-353633-a4pu6rlu	246	4	of	of	IN
cord-353633-a4pu6rlu	246	5	studies	study	NNS
cord-353633-a4pu6rlu	246	6	has	have	VBZ
cord-353633-a4pu6rlu	246	7	aimed	aim	VBN
cord-353633-a4pu6rlu	246	8	to	to	TO
cord-353633-a4pu6rlu	246	9	develop	develop	VB
cord-353633-a4pu6rlu	246	10	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	246	11	models	model	NNS
cord-353633-a4pu6rlu	246	12	with	with	IN
cord-353633-a4pu6rlu	246	13	the	the	DT
cord-353633-a4pu6rlu	246	14	use	use	NN
cord-353633-a4pu6rlu	246	15	of	of	IN
cord-353633-a4pu6rlu	246	16	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	246	17	(	(	-LRB-
cord-353633-a4pu6rlu	246	18	Table	Table	NNP
cord-353633-a4pu6rlu	246	19	3	3	CD
cord-353633-a4pu6rlu	246	20	)	)	-RRB-
cord-353633-a4pu6rlu	246	21	.	.	.
cord-353633-a4pu6rlu	247	1	When	when	WRB
cord-353633-a4pu6rlu	247	2	evaluating	evaluate	VBG
cord-353633-a4pu6rlu	247	3	the	the	DT
cord-353633-a4pu6rlu	247	4	results	result	NNS
cord-353633-a4pu6rlu	247	5	of	of	IN
cord-353633-a4pu6rlu	247	6	these	these	DT
cord-353633-a4pu6rlu	247	7	studies	study	NNS
cord-353633-a4pu6rlu	247	8	,	,	,
cord-353633-a4pu6rlu	247	9	we	-PRON-	PRP
cord-353633-a4pu6rlu	247	10	have	have	VBP
cord-353633-a4pu6rlu	247	11	to	to	TO
cord-353633-a4pu6rlu	247	12	keep	keep	VB
cord-353633-a4pu6rlu	247	13	in	in	IN
cord-353633-a4pu6rlu	247	14	mind	mind	NN
cord-353633-a4pu6rlu	247	15	the	the	DT
cord-353633-a4pu6rlu	247	16	limitations	limitation	NNS
cord-353633-a4pu6rlu	247	17	and	and	CC
cord-353633-a4pu6rlu	247	18	challenges	challenge	NNS
cord-353633-a4pu6rlu	247	19	related	relate	VBN
cord-353633-a4pu6rlu	247	20	to	to	IN
cord-353633-a4pu6rlu	247	21	such	such	JJ
cord-353633-a4pu6rlu	247	22	procedures	procedure	NNS
cord-353633-a4pu6rlu	247	23	,	,	,
cord-353633-a4pu6rlu	247	24	that	that	WDT
cord-353633-a4pu6rlu	247	25	are	be	VBP
cord-353633-a4pu6rlu	247	26	described	describe	VBN
cord-353633-a4pu6rlu	247	27	below	below	IN
cord-353633-a4pu6rlu	247	28	(	(	-LRB-
cord-353633-a4pu6rlu	247	29	8	8	CD
cord-353633-a4pu6rlu	247	30	.	.	.
cord-353633-a4pu6rlu	248	1	Conclusions	conclusion	NNS
cord-353633-a4pu6rlu	249	1	-Challenges	-Challenges	NNP
cord-353633-a4pu6rlu	249	2	-Perspectives	-Perspectives	NNP
cord-353633-a4pu6rlu	249	3	)	)	-RRB-
cord-353633-a4pu6rlu	249	4	.	.	.
cord-353633-a4pu6rlu	250	1	In	in	IN
cord-353633-a4pu6rlu	250	2	one	one	CD
cord-353633-a4pu6rlu	250	3	of	of	IN
cord-353633-a4pu6rlu	250	4	the	the	DT
cord-353633-a4pu6rlu	250	5	early	early	JJ
cord-353633-a4pu6rlu	250	6	efforts	effort	NNS
cord-353633-a4pu6rlu	250	7	,	,	,
cord-353633-a4pu6rlu	250	8	combined	combine	VBN
cord-353633-a4pu6rlu	250	9	genomic	genomic	NN
cord-353633-a4pu6rlu	250	10	/	/	SYM
cord-353633-a4pu6rlu	250	11	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	250	12	analysis	analysis	NN
cord-353633-a4pu6rlu	250	13	involving	involve	VBG
cord-353633-a4pu6rlu	250	14	liver	liver	NN
cord-353633-a4pu6rlu	250	15	tissues	tissue	NNS
cord-353633-a4pu6rlu	250	16	for	for	IN
cord-353633-a4pu6rlu	250	17	assessing	assess	VBG
cord-353633-a4pu6rlu	250	18	gene	gene	NN
cord-353633-a4pu6rlu	250	19	expression	expression	NN
cord-353633-a4pu6rlu	250	20	and	and	CC
cord-353633-a4pu6rlu	250	21	serum	serum	NN
cord-353633-a4pu6rlu	250	22	samples	sample	NNS
cord-353633-a4pu6rlu	250	23	for	for	IN
cord-353633-a4pu6rlu	250	24	assessing	assess	VBG
cord-353633-a4pu6rlu	250	25	proteins	protein	NNS
cord-353633-a4pu6rlu	250	26	was	be	VBD
cord-353633-a4pu6rlu	250	27	performed	perform	VBN
cord-353633-a4pu6rlu	250	28	in	in	IN
cord-353633-a4pu6rlu	250	29	patients	patient	NNS
cord-353633-a4pu6rlu	250	30	with	with	IN
cord-353633-a4pu6rlu	250	31	different	different	JJ
cord-353633-a4pu6rlu	250	32	stages	stage	NNS
cord-353633-a4pu6rlu	250	33	of	of	IN
cord-353633-a4pu6rlu	250	34	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	250	35	.	.	.
cord-353633-a4pu6rlu	251	1	A	a	DT
cord-353633-a4pu6rlu	251	2	SELDI	SELDI	NNP
cord-353633-a4pu6rlu	251	3	-	-	HYPH
cord-353633-a4pu6rlu	251	4	TOF	TOF	NNP
cord-353633-a4pu6rlu	251	5	mass	mass	NN
cord-353633-a4pu6rlu	251	6	spectrometry	spectrometry	NN
cord-353633-a4pu6rlu	251	7	(	(	-LRB-
cord-353633-a4pu6rlu	251	8	MS	MS	NNP
cord-353633-a4pu6rlu	251	9	)	)	-RRB-
cord-353633-a4pu6rlu	251	10	identified	identify	VBD
cord-353633-a4pu6rlu	251	11	approximately	approximately	RB
cord-353633-a4pu6rlu	251	12	300	300	CD
cord-353633-a4pu6rlu	251	13	protein	protein	NN
cord-353633-a4pu6rlu	251	14	peaks	peak	NNS
cord-353633-a4pu6rlu	251	15	with	with	IN
cord-353633-a4pu6rlu	251	16	16	16	CD
cord-353633-a4pu6rlu	251	17	of	of	IN
cord-353633-a4pu6rlu	251	18	them	-PRON-	PRP
cord-353633-a4pu6rlu	251	19	being	be	VBG
cord-353633-a4pu6rlu	251	20	significantly	significantly	RB
cord-353633-a4pu6rlu	251	21	different	different	JJ
cord-353633-a4pu6rlu	251	22	between	between	IN
cord-353633-a4pu6rlu	251	23	groups	group	NNS
cord-353633-a4pu6rlu	251	24	.	.	.
cord-353633-a4pu6rlu	252	1	At	at	IN
cord-353633-a4pu6rlu	252	2	that	that	DT
cord-353633-a4pu6rlu	252	3	timepoint	timepoint	NN
cord-353633-a4pu6rlu	252	4	,	,	,
cord-353633-a4pu6rlu	252	5	it	-PRON-	PRP
cord-353633-a4pu6rlu	252	6	was	be	VBD
cord-353633-a4pu6rlu	252	7	not	not	RB
cord-353633-a4pu6rlu	252	8	possible	possible	JJ
cord-353633-a4pu6rlu	252	9	to	to	TO
cord-353633-a4pu6rlu	252	10	identify	identify	VB
cord-353633-a4pu6rlu	252	11	in	in	IN
cord-353633-a4pu6rlu	252	12	which	which	WDT
cord-353633-a4pu6rlu	252	13	proteins	protein	NNS
cord-353633-a4pu6rlu	252	14	these	these	DT
cord-353633-a4pu6rlu	252	15	peaks	peak	NNS
cord-353633-a4pu6rlu	252	16	corresponded	correspond	VBD
cord-353633-a4pu6rlu	252	17	to	to	IN
cord-353633-a4pu6rlu	252	18	but	but	CC
cord-353633-a4pu6rlu	252	19	their	-PRON-	PRP$
cord-353633-a4pu6rlu	252	20	masses	masse	NNS
cord-353633-a4pu6rlu	252	21	were	be	VBD
cord-353633-a4pu6rlu	252	22	compared	compare	VBN
cord-353633-a4pu6rlu	252	23	with	with	IN
cord-353633-a4pu6rlu	252	24	the	the	DT
cord-353633-a4pu6rlu	252	25	masses	masse	NNS
cord-353633-a4pu6rlu	252	26	of	of	IN
cord-353633-a4pu6rlu	252	27	1,440	1,440	CD
cord-353633-a4pu6rlu	252	28	serum	serum	NN
cord-353633-a4pu6rlu	252	29	proteins	protein	NNS
cord-353633-a4pu6rlu	252	30	,	,	,
cord-353633-a4pu6rlu	252	31	which	which	WDT
cord-353633-a4pu6rlu	252	32	led	lead	VBD
cord-353633-a4pu6rlu	252	33	to	to	IN
cord-353633-a4pu6rlu	252	34	the	the	DT
cord-353633-a4pu6rlu	252	35	identification	identification	NN
cord-353633-a4pu6rlu	252	36	of	of	IN
cord-353633-a4pu6rlu	252	37	fibrinogen	fibrinogen	NN
cord-353633-a4pu6rlu	252	38	γ	γ	NN
cord-353633-a4pu6rlu	252	39	as	as	IN
cord-353633-a4pu6rlu	252	40	one	one	CD
cord-353633-a4pu6rlu	252	41	possible	possible	JJ
cord-353633-a4pu6rlu	252	42	biomarker	biomarker	NN
cord-353633-a4pu6rlu	252	43	[	[	-LRB-
cord-353633-a4pu6rlu	252	44	131	131	CD
cord-353633-a4pu6rlu	252	45	]	]	-RRB-
cord-353633-a4pu6rlu	252	46	.	.	.
cord-353633-a4pu6rlu	253	1	In	in	IN
cord-353633-a4pu6rlu	253	2	another	another	DT
cord-353633-a4pu6rlu	253	3	study	study	NN
cord-353633-a4pu6rlu	253	4	including	include	VBG
cord-353633-a4pu6rlu	253	5	eighty	eighty	CD
cord-353633-a4pu6rlu	253	6	morbidly	morbidly	RB
cord-353633-a4pu6rlu	253	7	obese	obese	JJ
cord-353633-a4pu6rlu	253	8	patients	patient	NNS
cord-353633-a4pu6rlu	253	9	,	,	,
cord-353633-a4pu6rlu	253	10	SELDI	SELDI	NNP
cord-353633-a4pu6rlu	253	11	-	-	HYPH
cord-353633-a4pu6rlu	253	12	TOF	TOF	NNP
cord-353633-a4pu6rlu	253	13	MS	MS	NNP
cord-353633-a4pu6rlu	253	14	has	have	VBZ
cord-353633-a4pu6rlu	253	15	identified	identify	VBN
cord-353633-a4pu6rlu	253	16	in	in	IN
cord-353633-a4pu6rlu	253	17	serum	serum	NN
cord-353633-a4pu6rlu	253	18	three	three	CD
cord-353633-a4pu6rlu	253	19	protein	protein	NN
cord-353633-a4pu6rlu	253	20	peaks	peak	NNS
cord-353633-a4pu6rlu	253	21	that	that	IN
cord-353633-a4pu6rlu	253	22	their	-PRON-	PRP$
cord-353633-a4pu6rlu	253	23	intensity	intensity	NN
cord-353633-a4pu6rlu	253	24	significantly	significantly	RB
cord-353633-a4pu6rlu	253	25	increased	increase	VBD
cord-353633-a4pu6rlu	253	26	with	with	IN
cord-353633-a4pu6rlu	253	27	the	the	DT
cord-353633-a4pu6rlu	253	28	severity	severity	NN
cord-353633-a4pu6rlu	253	29	of	of	IN
cord-353633-a4pu6rlu	253	30	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	253	31	,	,	,
cord-353633-a4pu6rlu	253	32	i.e.	i.e.	FW
cord-353633-a4pu6rlu	253	33	when	when	WRB
cord-353633-a4pu6rlu	253	34	moving	move	VBG
cord-353633-a4pu6rlu	253	35	from	from	IN
cord-353633-a4pu6rlu	253	36	steatosis	steatosis	NN
cord-353633-a4pu6rlu	253	37	to	to	IN
cord-353633-a4pu6rlu	253	38	NASH	NASH	NNP
cord-353633-a4pu6rlu	253	39	.	.	.
cord-353633-a4pu6rlu	254	1	None	none	NN
cord-353633-a4pu6rlu	254	2	of	of	IN
cord-353633-a4pu6rlu	254	3	these	these	DT
cord-353633-a4pu6rlu	254	4	peaks	peak	NNS
cord-353633-a4pu6rlu	254	5	correlated	correlate	VBN
cord-353633-a4pu6rlu	254	6	with	with	IN
cord-353633-a4pu6rlu	254	7	liver	liver	NN
cord-353633-a4pu6rlu	254	8	function	function	NN
cord-353633-a4pu6rlu	254	9	tests	test	NNS
cord-353633-a4pu6rlu	254	10	or	or	CC
cord-353633-a4pu6rlu	254	11	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	254	12	parameters	parameter	NNS
cord-353633-a4pu6rlu	254	13	and	and	CC
cord-353633-a4pu6rlu	254	14	all	all	DT
cord-353633-a4pu6rlu	254	15	of	of	IN
cord-353633-a4pu6rlu	254	16	them	-PRON-	PRP
cord-353633-a4pu6rlu	254	17	returned	return	VBD
cord-353633-a4pu6rlu	254	18	to	to	IN
cord-353633-a4pu6rlu	254	19	normal	normal	JJ
cord-353633-a4pu6rlu	254	20	after	after	IN
cord-353633-a4pu6rlu	254	21	bariatric	bariatric	JJ
cord-353633-a4pu6rlu	254	22	surgery	surgery	NN
cord-353633-a4pu6rlu	254	23	.	.	.
cord-353633-a4pu6rlu	255	1	With	with	IN
cord-353633-a4pu6rlu	255	2	immunoSELDI	immunoSELDI	NNS
cord-353633-a4pu6rlu	255	3	assay	assay	VBP
cord-353633-a4pu6rlu	255	4	these	these	DT
cord-353633-a4pu6rlu	255	5	peaks	peak	NNS
cord-353633-a4pu6rlu	255	6	were	be	VBD
cord-353633-a4pu6rlu	255	7	recognized	recognize	VBN
cord-353633-a4pu6rlu	255	8	as	as	IN
cord-353633-a4pu6rlu	255	9	alpha	alpha	NN
cord-353633-a4pu6rlu	255	10	-	-	HYPH
cord-353633-a4pu6rlu	255	11	and	and	CC
cord-353633-a4pu6rlu	255	12	beta	beta	NN
cord-353633-a4pu6rlu	255	13	-	-	HYPH
cord-353633-a4pu6rlu	255	14	hemoglobin	hemoglobin	NN
cord-353633-a4pu6rlu	255	15	subunits	subunit	NNS
cord-353633-a4pu6rlu	255	16	[	[	-LRB-
cord-353633-a4pu6rlu	255	17	132	132	CD
cord-353633-a4pu6rlu	255	18	]	]	-RRB-
cord-353633-a4pu6rlu	255	19	.	.	.
cord-353633-a4pu6rlu	256	1	One	one	CD
cord-353633-a4pu6rlu	256	2	of	of	IN
cord-353633-a4pu6rlu	256	3	the	the	DT
cord-353633-a4pu6rlu	256	4	most	most	RBS
cord-353633-a4pu6rlu	256	5	comprehensive	comprehensive	JJ
cord-353633-a4pu6rlu	256	6	studies	study	NNS
cord-353633-a4pu6rlu	256	7	so	so	RB
cord-353633-a4pu6rlu	256	8	far	far	RB
cord-353633-a4pu6rlu	256	9	was	be	VBD
cord-353633-a4pu6rlu	256	10	able	able	JJ
cord-353633-a4pu6rlu	256	11	to	to	TO
cord-353633-a4pu6rlu	256	12	identify	identify	VB
cord-353633-a4pu6rlu	256	13	1,700	1,700	CD
cord-353633-a4pu6rlu	256	14	serum	serum	NN
cord-353633-a4pu6rlu	256	15	proteins	protein	NNS
cord-353633-a4pu6rlu	256	16	in	in	IN
cord-353633-a4pu6rlu	256	17	a	a	DT
cord-353633-a4pu6rlu	256	18	population	population	NN
cord-353633-a4pu6rlu	256	19	with	with	IN
cord-353633-a4pu6rlu	256	20	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	256	21	.	.	.
cord-353633-a4pu6rlu	257	1	Among	among	IN
cord-353633-a4pu6rlu	257	2	them	-PRON-	PRP
cord-353633-a4pu6rlu	257	3	55	55	CD
cord-353633-a4pu6rlu	257	4	were	be	VBD
cord-353633-a4pu6rlu	257	5	significantly	significantly	RB
cord-353633-a4pu6rlu	257	6	different	different	JJ
cord-353633-a4pu6rlu	257	7	between	between	IN
cord-353633-a4pu6rlu	257	8	NALF	NALF	NNP
cord-353633-a4pu6rlu	257	9	and	and	CC
cord-353633-a4pu6rlu	257	10	NASH	NASH	NNP
cord-353633-a4pu6rlu	257	11	with	with	IN
cord-353633-a4pu6rlu	257	12	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	257	13	stage	stage	NN
cord-353633-a4pu6rlu	257	14	3	3	CD
cord-353633-a4pu6rlu	257	15	or	or	CC
cord-353633-a4pu6rlu	257	16	4	4	CD
cord-353633-a4pu6rlu	258	1	(	(	-LRB-
cord-353633-a4pu6rlu	258	2	F3	F3	NNP
cord-353633-a4pu6rlu	258	3	/	/	SYM
cord-353633-a4pu6rlu	258	4	F4	F4	NNP
cord-353633-a4pu6rlu	258	5	)	)	-RRB-
cord-353633-a4pu6rlu	258	6	and	and	CC
cord-353633-a4pu6rlu	258	7	15	15	CD
cord-353633-a4pu6rlu	258	8	between	between	IN
cord-353633-a4pu6rlu	258	9	NASH	NASH	NNP
cord-353633-a4pu6rlu	258	10	vs	vs	IN
cord-353633-a4pu6rlu	259	1	J	J	NNP
cord-353633-a4pu6rlu	259	2	o	o	NNP
cord-353633-a4pu6rlu	260	1	u	u	NNP
cord-353633-a4pu6rlu	260	2	r	r	NNP
cord-353633-a4pu6rlu	260	3	n	n	NN
cord-353633-a4pu6rlu	260	4	a	a	DT
cord-353633-a4pu6rlu	260	5	l	l	NN
cord-353633-a4pu6rlu	260	6	P	p	NN
cord-353633-a4pu6rlu	260	7	r	r	NN
cord-353633-a4pu6rlu	260	8	e	e	NN
cord-353633-a4pu6rlu	260	9	-p	-p	NN
cord-353633-a4pu6rlu	260	10	r	r	NN
cord-353633-a4pu6rlu	260	11	o	o	NN
cord-353633-a4pu6rlu	260	12	o	o	NN
cord-353633-a4pu6rlu	260	13	f	f	NN
cord-353633-a4pu6rlu	260	14	34	34	CD
cord-353633-a4pu6rlu	260	15	NASH	NASH	NNP
cord-353633-a4pu6rlu	260	16	F3	F3	NNP
cord-353633-a4pu6rlu	260	17	/	/	SYM
cord-353633-a4pu6rlu	260	18	F4	F4	NNP
cord-353633-a4pu6rlu	260	19	group	group	NN
cord-353633-a4pu6rlu	260	20	.	.	.
cord-353633-a4pu6rlu	261	1	These	these	DT
cord-353633-a4pu6rlu	261	2	proteins	protein	NNS
cord-353633-a4pu6rlu	261	3	were	be	VBD
cord-353633-a4pu6rlu	261	4	involved	involve	VBN
cord-353633-a4pu6rlu	261	5	in	in	IN
cord-353633-a4pu6rlu	261	6	immune	immune	JJ
cord-353633-a4pu6rlu	261	7	system	system	NN
cord-353633-a4pu6rlu	261	8	regulation	regulation	NN
cord-353633-a4pu6rlu	261	9	and	and	CC
cord-353633-a4pu6rlu	261	10	inflammation	inflammation	NN
cord-353633-a4pu6rlu	261	11	,	,	,
cord-353633-a4pu6rlu	261	12	in	in	IN
cord-353633-a4pu6rlu	261	13	coagulation	coagulation	NN
cord-353633-a4pu6rlu	261	14	cascades	cascade	NNS
cord-353633-a4pu6rlu	261	15	(	(	-LRB-
cord-353633-a4pu6rlu	261	16	including	include	VBG
cord-353633-a4pu6rlu	261	17	fibrinogen	fibrinogen	NN
cord-353633-a4pu6rlu	261	18	γ	γ	NN
cord-353633-a4pu6rlu	261	19	demonstrated	demonstrate	VBN
cord-353633-a4pu6rlu	261	20	by	by	IN
cord-353633-a4pu6rlu	261	21	previous	previous	JJ
cord-353633-a4pu6rlu	261	22	studies	study	NNS
cord-353633-a4pu6rlu	261	23	)	)	-RRB-
cord-353633-a4pu6rlu	261	24	,	,	,
cord-353633-a4pu6rlu	261	25	in	in	IN
cord-353633-a4pu6rlu	261	26	cell	cell	NN
cord-353633-a4pu6rlu	261	27	growth	growth	NN
cord-353633-a4pu6rlu	261	28	and	and	CC
cord-353633-a4pu6rlu	261	29	proliferation	proliferation	NN
cord-353633-a4pu6rlu	261	30	(	(	-LRB-
cord-353633-a4pu6rlu	261	31	including	include	VBG
cord-353633-a4pu6rlu	261	32	IGFBP2	igfbp2	NN
cord-353633-a4pu6rlu	261	33	,	,	,
cord-353633-a4pu6rlu	261	34	IGFBP3	IGFBP3	NNP
cord-353633-a4pu6rlu	261	35	,	,	,
cord-353633-a4pu6rlu	261	36	also	also	RB
cord-353633-a4pu6rlu	261	37	shown	show	VBN
cord-353633-a4pu6rlu	261	38	in	in	IN
cord-353633-a4pu6rlu	261	39	targeted	target	VBN
cord-353633-a4pu6rlu	261	40	approaches	approach	NNS
cord-353633-a4pu6rlu	261	41	to	to	TO
cord-353633-a4pu6rlu	261	42	be	be	VB
cord-353633-a4pu6rlu	261	43	relevant	relevant	JJ
cord-353633-a4pu6rlu	261	44	[	[	-LRB-
cord-353633-a4pu6rlu	261	45	133	133	CD
cord-353633-a4pu6rlu	261	46	]	]	-RRB-
cord-353633-a4pu6rlu	261	47	)	)	-RRB-
cord-353633-a4pu6rlu	261	48	and	and	CC
cord-353633-a4pu6rlu	261	49	many	many	JJ
cord-353633-a4pu6rlu	261	50	of	of	IN
cord-353633-a4pu6rlu	261	51	them	-PRON-	PRP
cord-353633-a4pu6rlu	261	52	were	be	VBD
cord-353633-a4pu6rlu	261	53	apolipoproteins	apolipoprotein	NNS
cord-353633-a4pu6rlu	261	54	(	(	-LRB-
cord-353633-a4pu6rlu	261	55	demonstrated	demonstrate	VBN
cord-353633-a4pu6rlu	261	56	also	also	RB
cord-353633-a4pu6rlu	261	57	in	in	IN
cord-353633-a4pu6rlu	261	58	[	[	-LRB-
cord-353633-a4pu6rlu	261	59	134	134	CD
cord-353633-a4pu6rlu	261	60	]	]	-RRB-
cord-353633-a4pu6rlu	261	61	)	)	-RRB-
cord-353633-a4pu6rlu	261	62	and	and	CC
cord-353633-a4pu6rlu	261	63	blood	blood	NN
cord-353633-a4pu6rlu	261	64	carrier	carrier	NN
cord-353633-a4pu6rlu	261	65	proteins	protein	NNS
cord-353633-a4pu6rlu	261	66	.	.	.
cord-353633-a4pu6rlu	262	1	Six	six	CD
cord-353633-a4pu6rlu	262	2	(	(	-LRB-
cord-353633-a4pu6rlu	262	3	fibrinogen	fibrinogen	NN
cord-353633-a4pu6rlu	262	4	β	β	XX
cord-353633-a4pu6rlu	262	5	chain	chain	NN
cord-353633-a4pu6rlu	262	6	,	,	,
cord-353633-a4pu6rlu	262	7	retinol	retinol	NN
cord-353633-a4pu6rlu	262	8	binding	bind	VBG
cord-353633-a4pu6rlu	262	9	protein	protein	NN
cord-353633-a4pu6rlu	262	10	4	4	CD
cord-353633-a4pu6rlu	262	11	,	,	,
cord-353633-a4pu6rlu	262	12	serum	serum	NN
cord-353633-a4pu6rlu	262	13	amyloid	amyloid	NN
cord-353633-a4pu6rlu	262	14	P	p	NN
cord-353633-a4pu6rlu	262	15	component	component	NN
cord-353633-a4pu6rlu	262	16	,	,	,
cord-353633-a4pu6rlu	262	17	lumican	lumican	NNP
cord-353633-a4pu6rlu	262	18	,	,	,
cord-353633-a4pu6rlu	262	19	transgelin	transgelin	NNP
cord-353633-a4pu6rlu	262	20	2	2	CD
cord-353633-a4pu6rlu	262	21	,	,	,
cord-353633-a4pu6rlu	262	22	and	and	CC
cord-353633-a4pu6rlu	262	23	CD5	CD5	NNP
cord-353633-a4pu6rlu	262	24	antigen	antigen	NN
cord-353633-a4pu6rlu	262	25	-	-	HYPH
cord-353633-a4pu6rlu	262	26	like	like	JJ
cord-353633-a4pu6rlu	262	27	)	)	-RRB-
cord-353633-a4pu6rlu	262	28	were	be	VBD
cord-353633-a4pu6rlu	262	29	selected	select	VBN
cord-353633-a4pu6rlu	262	30	to	to	TO
cord-353633-a4pu6rlu	262	31	create	create	VB
cord-353633-a4pu6rlu	262	32	a	a	DT
cord-353633-a4pu6rlu	262	33	panel	panel	NN
cord-353633-a4pu6rlu	262	34	for	for	IN
cord-353633-a4pu6rlu	262	35	the	the	DT
cord-353633-a4pu6rlu	262	36	non	non	JJ
cord-353633-a4pu6rlu	262	37	-	-	JJ
cord-353633-a4pu6rlu	262	38	differential	differential	JJ
cord-353633-a4pu6rlu	262	39	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	262	40	of	of	IN
cord-353633-a4pu6rlu	262	41	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	262	42	and	and	CC
cord-353633-a4pu6rlu	262	43	its	-PRON-	PRP$
cord-353633-a4pu6rlu	262	44	stages	stage	NNS
cord-353633-a4pu6rlu	262	45	,	,	,
cord-353633-a4pu6rlu	262	46	ranging	range	VBG
cord-353633-a4pu6rlu	262	47	from	from	IN
cord-353633-a4pu6rlu	262	48	healthy	healthy	JJ
cord-353633-a4pu6rlu	262	49	liver	liver	NN
cord-353633-a4pu6rlu	262	50	status	status	NN
cord-353633-a4pu6rlu	262	51	to	to	IN
cord-353633-a4pu6rlu	262	52	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	262	53	,	,	,
cord-353633-a4pu6rlu	262	54	NASH	NASH	NNP
cord-353633-a4pu6rlu	262	55	or	or	CC
cord-353633-a4pu6rlu	262	56	NASH	NASH	NNP
cord-353633-a4pu6rlu	262	57	with	with	IN
cord-353633-a4pu6rlu	262	58	F3	F3	NNP
cord-353633-a4pu6rlu	262	59	/	/	SYM
cord-353633-a4pu6rlu	262	60	F4	f4	NN
cord-353633-a4pu6rlu	262	61	showing	show	VBG
cord-353633-a4pu6rlu	262	62	good	good	JJ
cord-353633-a4pu6rlu	262	63	to	to	IN
cord-353633-a4pu6rlu	262	64	very	very	RB
cord-353633-a4pu6rlu	262	65	good	good	JJ
cord-353633-a4pu6rlu	262	66	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	262	67	accuracy	accuracy	NN
cord-353633-a4pu6rlu	262	68	(	(	-LRB-
cord-353633-a4pu6rlu	262	69	AUROCs	AUROCs	NNP
cord-353633-a4pu6rlu	262	70	1.0	1.0	CD
cord-353633-a4pu6rlu	262	71	,	,	,
cord-353633-a4pu6rlu	262	72	0.83	0.83	CD
cord-353633-a4pu6rlu	262	73	,	,	,
cord-353633-a4pu6rlu	262	74	0.86	0.86	CD
cord-353633-a4pu6rlu	262	75	,	,	,
cord-353633-a4pu6rlu	262	76	0.91	0.91	CD
cord-353633-a4pu6rlu	262	77	,	,	,
cord-353633-a4pu6rlu	262	78	respectively	respectively	RB
cord-353633-a4pu6rlu	262	79	)	)	-RRB-
cord-353633-a4pu6rlu	262	80	.	.	.
cord-353633-a4pu6rlu	263	1	This	this	DT
cord-353633-a4pu6rlu	263	2	was	be	VBD
cord-353633-a4pu6rlu	263	3	though	though	IN
cord-353633-a4pu6rlu	263	4	a	a	DT
cord-353633-a4pu6rlu	263	5	study	study	NN
cord-353633-a4pu6rlu	263	6	with	with	IN
cord-353633-a4pu6rlu	263	7	small	small	JJ
cord-353633-a4pu6rlu	263	8	sample	sample	NN
cord-353633-a4pu6rlu	263	9	size	size	NN
cord-353633-a4pu6rlu	263	10	and	and	CC
cord-353633-a4pu6rlu	263	11	its	-PRON-	PRP$
cord-353633-a4pu6rlu	263	12	findings	finding	NNS
cord-353633-a4pu6rlu	263	13	have	have	VBP
cord-353633-a4pu6rlu	263	14	not	not	RB
cord-353633-a4pu6rlu	263	15	been	be	VBN
cord-353633-a4pu6rlu	263	16	replicated	replicate	VBN
cord-353633-a4pu6rlu	263	17	so	so	RB
cord-353633-a4pu6rlu	263	18	far	far	RB
cord-353633-a4pu6rlu	263	19	[	[	-LRB-
cord-353633-a4pu6rlu	263	20	135	135	CD
cord-353633-a4pu6rlu	263	21	]	]	-RRB-
cord-353633-a4pu6rlu	263	22	.	.	.
cord-353633-a4pu6rlu	264	1	In	in	IN
cord-353633-a4pu6rlu	264	2	another	another	DT
cord-353633-a4pu6rlu	264	3	approach	approach	NN
cord-353633-a4pu6rlu	264	4	,	,	,
cord-353633-a4pu6rlu	264	5	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	264	6	models	model	NNS
cord-353633-a4pu6rlu	264	7	for	for	IN
cord-353633-a4pu6rlu	264	8	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	264	9	between	between	IN
cord-353633-a4pu6rlu	264	10	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	264	11	vs	vs	IN
cord-353633-a4pu6rlu	264	12	healthy	healthy	JJ
cord-353633-a4pu6rlu	264	13	controls	control	NNS
cord-353633-a4pu6rlu	264	14	among	among	IN
cord-353633-a4pu6rlu	264	15	the	the	DT
cord-353633-a4pu6rlu	264	16	obese	obese	JJ
cord-353633-a4pu6rlu	264	17	population	population	NN
cord-353633-a4pu6rlu	264	18	undergoing	undergo	VBG
cord-353633-a4pu6rlu	264	19	bariatric	bariatric	JJ
cord-353633-a4pu6rlu	264	20	surgery	surgery	NN
cord-353633-a4pu6rlu	264	21	were	be	VBD
cord-353633-a4pu6rlu	264	22	developed	develop	VBN
cord-353633-a4pu6rlu	264	23	.	.	.
cord-353633-a4pu6rlu	265	1	These	these	DT
cord-353633-a4pu6rlu	265	2	models	model	NNS
cord-353633-a4pu6rlu	265	3	combined	combine	VBD
cord-353633-a4pu6rlu	265	4	genomic	genomic	JJ
cord-353633-a4pu6rlu	265	5	information	information	NN
cord-353633-a4pu6rlu	265	6	and	and	CC
cord-353633-a4pu6rlu	265	7	especially	especially	RB
cord-353633-a4pu6rlu	265	8	the	the	DT
cord-353633-a4pu6rlu	265	9	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	265	10	genotype	genotype	NN
cord-353633-a4pu6rlu	265	11	,	,	,
cord-353633-a4pu6rlu	265	12	phenomic	phenomic	NNP
cord-353633-a4pu6rlu	265	13	data	datum	NNS
cord-353633-a4pu6rlu	265	14	(	(	-LRB-
cord-353633-a4pu6rlu	265	15	i.e.	i.e.	FW
cord-353633-a4pu6rlu	265	16	selected	select	VBN
cord-353633-a4pu6rlu	265	17	biochemical	biochemical	JJ
cord-353633-a4pu6rlu	265	18	measurements	measurement	NNS
cord-353633-a4pu6rlu	265	19	such	such	JJ
cord-353633-a4pu6rlu	265	20	as	as	IN
cord-353633-a4pu6rlu	265	21	glucose	glucose	NN
cord-353633-a4pu6rlu	265	22	,	,	,
cord-353633-a4pu6rlu	265	23	insulin	insulin	NN
cord-353633-a4pu6rlu	265	24	,	,	,
cord-353633-a4pu6rlu	265	25	lipid	lipid	NN
cord-353633-a4pu6rlu	265	26	profile	profile	NN
cord-353633-a4pu6rlu	265	27	,	,	,
cord-353633-a4pu6rlu	265	28	ALT	ALT	NNP
cord-353633-a4pu6rlu	265	29	)	)	-RRB-
cord-353633-a4pu6rlu	265	30	and	and	CC
cord-353633-a4pu6rlu	265	31	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	265	32	data	datum	NNS
cord-353633-a4pu6rlu	265	33	.	.	.
cord-353633-a4pu6rlu	266	1	Specifically	specifically	RB
cord-353633-a4pu6rlu	266	2	,	,	,
cord-353633-a4pu6rlu	266	3	a	a	DT
cord-353633-a4pu6rlu	266	4	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	266	5	analysis	analysis	NN
cord-353633-a4pu6rlu	266	6	identified	identify	VBD
cord-353633-a4pu6rlu	266	7	1129	1129	CD
cord-353633-a4pu6rlu	266	8	proteins	protein	NNS
cord-353633-a4pu6rlu	266	9	with	with	IN
cord-353633-a4pu6rlu	266	10	30	30	CD
cord-353633-a4pu6rlu	266	11	of	of	IN
cord-353633-a4pu6rlu	266	12	them	-PRON-	PRP
cord-353633-a4pu6rlu	266	13	being	be	VBG
cord-353633-a4pu6rlu	266	14	significantly	significantly	RB
cord-353633-a4pu6rlu	266	15	different	different	JJ
cord-353633-a4pu6rlu	266	16	between	between	IN
cord-353633-a4pu6rlu	266	17	the	the	DT
cord-353633-a4pu6rlu	266	18	two	two	CD
cord-353633-a4pu6rlu	266	19	groups	group	NNS
cord-353633-a4pu6rlu	266	20	.	.	.
cord-353633-a4pu6rlu	267	1	Among	among	IN
cord-353633-a4pu6rlu	267	2	them	-PRON-	PRP
cord-353633-a4pu6rlu	267	3	was	be	VBD
cord-353633-a4pu6rlu	267	4	aminoacylase-1	aminoacylase-1	NNP
cord-353633-a4pu6rlu	267	5	,	,	,
cord-353633-a4pu6rlu	267	6	sex	sex	NN
cord-353633-a4pu6rlu	267	7	hormonebinding	hormonebinding	NN
cord-353633-a4pu6rlu	267	8	globulin	globulin	NN
cord-353633-a4pu6rlu	267	9	,	,	,
cord-353633-a4pu6rlu	267	10	Galectin-3	Galectin-3	NNP
cord-353633-a4pu6rlu	267	11	,	,	,
cord-353633-a4pu6rlu	267	12	antithrombin	antithrombin	NN
cord-353633-a4pu6rlu	267	13	III	III	NNP
cord-353633-a4pu6rlu	267	14	and	and	CC
cord-353633-a4pu6rlu	267	15	the	the	DT
cord-353633-a4pu6rlu	267	16	hepatocyte	hepatocyte	NN
cord-353633-a4pu6rlu	267	17	growth	growth	NN
cord-353633-a4pu6rlu	267	18	factor	factor	NN
cord-353633-a4pu6rlu	267	19	.	.	.
cord-353633-a4pu6rlu	268	1	Logistic	logistic	JJ
cord-353633-a4pu6rlu	268	2	regression	regression	NN
cord-353633-a4pu6rlu	268	3	models	model	NNS
cord-353633-a4pu6rlu	268	4	for	for	IN
cord-353633-a4pu6rlu	268	5	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	268	6	between	between	IN
cord-353633-a4pu6rlu	268	7	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	268	8	and	and	CC
cord-353633-a4pu6rlu	268	9	healthy	healthy	JJ
cord-353633-a4pu6rlu	268	10	status	status	NN
cord-353633-a4pu6rlu	268	11	were	be	VBD
cord-353633-a4pu6rlu	268	12	trained	train	VBN
cord-353633-a4pu6rlu	268	13	by	by	IN
cord-353633-a4pu6rlu	268	14	using	use	VBG
cord-353633-a4pu6rlu	268	15	each	each	DT
cord-353633-a4pu6rlu	268	16	type	type	NN
cord-353633-a4pu6rlu	268	17	of	of	IN
cord-353633-a4pu6rlu	268	18	data	datum	NNS
cord-353633-a4pu6rlu	268	19	individually	individually	RB
cord-353633-a4pu6rlu	268	20	(	(	-LRB-
cord-353633-a4pu6rlu	268	21	i.e.	i.e.	FW
cord-353633-a4pu6rlu	268	22	genomic	genomic	JJ
cord-353633-a4pu6rlu	268	23	,	,	,
cord-353633-a4pu6rlu	268	24	However	however	RB
cord-353633-a4pu6rlu	268	25	,	,	,
cord-353633-a4pu6rlu	268	26	the	the	DT
cord-353633-a4pu6rlu	268	27	utility	utility	NN
cord-353633-a4pu6rlu	268	28	of	of	IN
cord-353633-a4pu6rlu	268	29	such	such	JJ
cord-353633-a4pu6rlu	268	30	algorithms	algorithm	NNS
cord-353633-a4pu6rlu	268	31	is	be	VBZ
cord-353633-a4pu6rlu	268	32	questionable	questionable	JJ
cord-353633-a4pu6rlu	268	33	given	give	VBN
cord-353633-a4pu6rlu	268	34	that	that	DT
cord-353633-a4pu6rlu	268	35	ultrasound	ultrasound	NN
cord-353633-a4pu6rlu	268	36	or	or	CC
cord-353633-a4pu6rlu	268	37	other	other	JJ
cord-353633-a4pu6rlu	268	38	simpler	simple	JJR
cord-353633-a4pu6rlu	268	39	algorithms	algorithm	NNS
cord-353633-a4pu6rlu	268	40	(	(	-LRB-
cord-353633-a4pu6rlu	268	41	e.g.	e.g.	IN
cord-353633-a4pu6rlu	268	42	fatty	fatty	JJ
cord-353633-a4pu6rlu	268	43	liver	liver	NN
cord-353633-a4pu6rlu	268	44	index	index	NN
cord-353633-a4pu6rlu	268	45	,	,	,
cord-353633-a4pu6rlu	268	46	etc	etc	FW
cord-353633-a4pu6rlu	268	47	.	.	.
cord-353633-a4pu6rlu	268	48	)	)	-RRB-
cord-353633-a4pu6rlu	269	1	show	show	VB
cord-353633-a4pu6rlu	269	2	similar	similar	JJ
cord-353633-a4pu6rlu	269	3	or	or	CC
cord-353633-a4pu6rlu	269	4	higher	high	JJR
cord-353633-a4pu6rlu	269	5	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	269	6	and	and	CC
cord-353633-a4pu6rlu	269	7	specificity	specificity	NN
cord-353633-a4pu6rlu	269	8	.	.	.
cord-353633-a4pu6rlu	270	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	270	2	,	,	,
cord-353633-a4pu6rlu	270	3	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	270	4	simply	simply	RB
cord-353633-a4pu6rlu	270	5	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	270	6	does	do	VBZ
cord-353633-a4pu6rlu	270	7	not	not	RB
cord-353633-a4pu6rlu	270	8	initiate	initiate	VB
cord-353633-a4pu6rlu	270	9	treatment	treatment	NN
cord-353633-a4pu6rlu	270	10	decisions	decision	NNS
cord-353633-a4pu6rlu	270	11	[	[	-LRB-
cord-353633-a4pu6rlu	270	12	136	136	CD
cord-353633-a4pu6rlu	270	13	]	]	-RRB-
cord-353633-a4pu6rlu	270	14	.	.	.
cord-353633-a4pu6rlu	271	1	Other	other	JJ
cord-353633-a4pu6rlu	271	2	studies	study	NNS
cord-353633-a4pu6rlu	271	3	performed	perform	VBD
cord-353633-a4pu6rlu	271	4	first	first	RB
cord-353633-a4pu6rlu	271	5	a	a	DT
cord-353633-a4pu6rlu	271	6	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	271	7	analysis	analysis	NN
cord-353633-a4pu6rlu	271	8	in	in	IN
cord-353633-a4pu6rlu	271	9	a	a	DT
cord-353633-a4pu6rlu	271	10	relevant	relevant	JJ
cord-353633-a4pu6rlu	271	11	condition	condition	NN
cord-353633-a4pu6rlu	271	12	or	or	CC
cord-353633-a4pu6rlu	271	13	in	in	IN
cord-353633-a4pu6rlu	271	14	another	another	DT
cord-353633-a4pu6rlu	271	15	species	species	NN
cord-353633-a4pu6rlu	271	16	and	and	CC
cord-353633-a4pu6rlu	271	17	then	then	RB
cord-353633-a4pu6rlu	271	18	tested	test	VBD
cord-353633-a4pu6rlu	271	19	their	-PRON-	PRP$
cord-353633-a4pu6rlu	271	20	findings	finding	NNS
cord-353633-a4pu6rlu	271	21	in	in	IN
cord-353633-a4pu6rlu	271	22	patients	patient	NNS
cord-353633-a4pu6rlu	271	23	with	with	IN
cord-353633-a4pu6rlu	271	24	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	271	25	.	.	.
cord-353633-a4pu6rlu	272	1	For	for	IN
cord-353633-a4pu6rlu	272	2	example	example	NN
cord-353633-a4pu6rlu	272	3	,	,	,
cord-353633-a4pu6rlu	272	4	in	in	IN
cord-353633-a4pu6rlu	272	5	one	one	CD
cord-353633-a4pu6rlu	272	6	study	study	NN
cord-353633-a4pu6rlu	272	7	,	,	,
cord-353633-a4pu6rlu	272	8	an	an	DT
cord-353633-a4pu6rlu	272	9	HCC	HCC	NNP
cord-353633-a4pu6rlu	272	10	pig	pig	NN
cord-353633-a4pu6rlu	272	11	model	model	NN
cord-353633-a4pu6rlu	272	12	was	be	VBD
cord-353633-a4pu6rlu	272	13	used	use	VBN
cord-353633-a4pu6rlu	272	14	and	and	CC
cord-353633-a4pu6rlu	272	15	a	a	DT
cord-353633-a4pu6rlu	272	16	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	272	17	analysis	analysis	NN
cord-353633-a4pu6rlu	272	18	in	in	IN
cord-353633-a4pu6rlu	272	19	serum	serum	NN
cord-353633-a4pu6rlu	272	20	was	be	VBD
cord-353633-a4pu6rlu	272	21	performed	perform	VBN
cord-353633-a4pu6rlu	272	22	.	.	.
cord-353633-a4pu6rlu	273	1	The	the	DT
cord-353633-a4pu6rlu	273	2	subsequent	subsequent	JJ
cord-353633-a4pu6rlu	273	3	analysis	analysis	NN
cord-353633-a4pu6rlu	273	4	identified	identify	VBD
cord-353633-a4pu6rlu	273	5	the	the	DT
cord-353633-a4pu6rlu	273	6	serum	serum	NN
cord-353633-a4pu6rlu	273	7	interalpha	interalpha	NN
cord-353633-a4pu6rlu	273	8	-	-	HYPH
cord-353633-a4pu6rlu	273	9	trypsin	trypsin	NN
cord-353633-a4pu6rlu	273	10	inhibitor	inhibitor	NN
cord-353633-a4pu6rlu	273	11	heavy	heavy	JJ
cord-353633-a4pu6rlu	273	12	chain	chain	NN
cord-353633-a4pu6rlu	273	13	4	4	CD
cord-353633-a4pu6rlu	273	14	as	as	IN
cord-353633-a4pu6rlu	273	15	the	the	DT
cord-353633-a4pu6rlu	273	16	most	most	RBS
cord-353633-a4pu6rlu	273	17	important	important	JJ
cord-353633-a4pu6rlu	273	18	protein	protein	NN
cord-353633-a4pu6rlu	273	19	corresponding	correspond	VBG
cord-353633-a4pu6rlu	273	20	with	with	IN
cord-353633-a4pu6rlu	273	21	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	273	22	progression	progression	NN
cord-353633-a4pu6rlu	273	23	and	and	CC
cord-353633-a4pu6rlu	273	24	HCC	HCC	NNP
cord-353633-a4pu6rlu	273	25	development	development	NN
cord-353633-a4pu6rlu	273	26	.	.	.
cord-353633-a4pu6rlu	274	1	This	this	DT
cord-353633-a4pu6rlu	274	2	was	be	VBD
cord-353633-a4pu6rlu	274	3	further	further	RB
cord-353633-a4pu6rlu	274	4	tested	test	VBN
cord-353633-a4pu6rlu	274	5	in	in	IN
cord-353633-a4pu6rlu	274	6	human	human	JJ
cord-353633-a4pu6rlu	274	7	serum	serum	NN
cord-353633-a4pu6rlu	274	8	samples	sample	NNS
cord-353633-a4pu6rlu	274	9	and	and	CC
cord-353633-a4pu6rlu	274	10	showed	show	VBD
cord-353633-a4pu6rlu	274	11	that	that	IN
cord-353633-a4pu6rlu	274	12	the	the	DT
cord-353633-a4pu6rlu	274	13	levels	level	NNS
cord-353633-a4pu6rlu	274	14	of	of	IN
cord-353633-a4pu6rlu	274	15	the	the	DT
cord-353633-a4pu6rlu	274	16	proteins	protein	NNS
cord-353633-a4pu6rlu	274	17	were	be	VBD
cord-353633-a4pu6rlu	274	18	higher	high	JJR
cord-353633-a4pu6rlu	274	19	in	in	IN
cord-353633-a4pu6rlu	274	20	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	274	21	patients	patient	NNS
cord-353633-a4pu6rlu	274	22	with	with	IN
cord-353633-a4pu6rlu	274	23	HCC	HCC	NNP
cord-353633-a4pu6rlu	274	24	compared	compare	VBN
cord-353633-a4pu6rlu	274	25	to	to	IN
cord-353633-a4pu6rlu	274	26	those	those	DT
cord-353633-a4pu6rlu	274	27	without	without	IN
cord-353633-a4pu6rlu	274	28	[	[	-LRB-
cord-353633-a4pu6rlu	274	29	137	137	CD
cord-353633-a4pu6rlu	274	30	]	]	-RRB-
cord-353633-a4pu6rlu	274	31	.	.	.
cord-353633-a4pu6rlu	275	1	Similarly	similarly	RB
cord-353633-a4pu6rlu	275	2	,	,	,
cord-353633-a4pu6rlu	275	3	in	in	IN
cord-353633-a4pu6rlu	275	4	another	another	DT
cord-353633-a4pu6rlu	275	5	study	study	NN
cord-353633-a4pu6rlu	275	6	a	a	DT
cord-353633-a4pu6rlu	275	7	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	275	8	analysis	analysis	NN
cord-353633-a4pu6rlu	275	9	in	in	IN
cord-353633-a4pu6rlu	275	10	plasma	plasma	NN
cord-353633-a4pu6rlu	275	11	of	of	IN
cord-353633-a4pu6rlu	275	12	patients	patient	NNS
cord-353633-a4pu6rlu	275	13	with	with	IN
cord-353633-a4pu6rlu	275	14	liver	liver	NN
cord-353633-a4pu6rlu	275	15	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	275	16	vs	vs	IN
cord-353633-a4pu6rlu	275	17	healthy	healthy	JJ
cord-353633-a4pu6rlu	275	18	ones	one	NNS
cord-353633-a4pu6rlu	275	19	was	be	VBD
cord-353633-a4pu6rlu	275	20	performed	perform	VBN
cord-353633-a4pu6rlu	275	21	.	.	.
cord-353633-a4pu6rlu	276	1	This	this	DT
cord-353633-a4pu6rlu	276	2	identified	identify	VBD
cord-353633-a4pu6rlu	276	3	57	57	CD
cord-353633-a4pu6rlu	276	4	significantly	significantly	RB
cord-353633-a4pu6rlu	276	5	different	different	JJ
cord-353633-a4pu6rlu	276	6	proteins	protein	NNS
cord-353633-a4pu6rlu	276	7	which	which	WDT
cord-353633-a4pu6rlu	276	8	were	be	VBD
cord-353633-a4pu6rlu	276	9	involved	involve	VBN
cord-353633-a4pu6rlu	276	10	in	in	IN
cord-353633-a4pu6rlu	276	11	immune	immune	JJ
cord-353633-a4pu6rlu	276	12	system	system	NN
cord-353633-a4pu6rlu	276	13	regulation	regulation	NN
cord-353633-a4pu6rlu	276	14	,	,	,
cord-353633-a4pu6rlu	276	15	inflammation	inflammation	NN
cord-353633-a4pu6rlu	276	16	,	,	,
cord-353633-a4pu6rlu	276	17	coagulation	coagulation	NN
cord-353633-a4pu6rlu	276	18	and	and	CC
cord-353633-a4pu6rlu	276	19	fibrinolysis	fibrinolysis	NN
cord-353633-a4pu6rlu	276	20	.	.	.
cord-353633-a4pu6rlu	277	1	Several	several	JJ
cord-353633-a4pu6rlu	277	2	of	of	IN
cord-353633-a4pu6rlu	277	3	these	these	DT
cord-353633-a4pu6rlu	277	4	proteins	protein	NNS
cord-353633-a4pu6rlu	277	5	were	be	VBD
cord-353633-a4pu6rlu	277	6	subsequently	subsequently	RB
cord-353633-a4pu6rlu	277	7	tested	test	VBN
cord-353633-a4pu6rlu	277	8	in	in	IN
cord-353633-a4pu6rlu	277	9	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	277	10	patients	patient	NNS
cord-353633-a4pu6rlu	277	11	and	and	CC
cord-353633-a4pu6rlu	277	12	were	be	VBD
cord-353633-a4pu6rlu	277	13	significantly	significantly	RB
cord-353633-a4pu6rlu	277	14	different	different	JJ
cord-353633-a4pu6rlu	277	15	in	in	IN
cord-353633-a4pu6rlu	277	16	people	people	NNS
cord-353633-a4pu6rlu	277	17	with	with	IN
cord-353633-a4pu6rlu	277	18	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	277	19	and	and	CC
cord-353633-a4pu6rlu	277	20	normal	normal	JJ
cord-353633-a4pu6rlu	277	21	glucose	glucose	NN
cord-353633-a4pu6rlu	277	22	tolerance	tolerance	NN
cord-353633-a4pu6rlu	277	23	compared	compare	VBN
cord-353633-a4pu6rlu	277	24	to	to	IN
cord-353633-a4pu6rlu	277	25	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	277	26	with	with	IN
cord-353633-a4pu6rlu	277	27	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	277	28	[	[	-LRB-
cord-353633-a4pu6rlu	277	29	138	138	CD
cord-353633-a4pu6rlu	277	30	]	]	-RRB-
cord-353633-a4pu6rlu	277	31	.	.	.
cord-353633-a4pu6rlu	278	1	Proteomic	Proteomic	NNP
cord-353633-a4pu6rlu	278	2	studies	study	NNS
cord-353633-a4pu6rlu	278	3	have	have	VBP
cord-353633-a4pu6rlu	278	4	rather	rather	RB
cord-353633-a4pu6rlu	278	5	limited	limit	VBN
cord-353633-a4pu6rlu	278	6	contribution	contribution	NN
cord-353633-a4pu6rlu	278	7	to	to	IN
cord-353633-a4pu6rlu	278	8	drug	drug	NN
cord-353633-a4pu6rlu	278	9	development	development	NN
cord-353633-a4pu6rlu	278	10	against	against	IN
cord-353633-a4pu6rlu	278	11	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	278	12	so	so	RB
cord-353633-a4pu6rlu	278	13	far	far	RB
cord-353633-a4pu6rlu	278	14	.	.	.
cord-353633-a4pu6rlu	279	1	Most	Most	JJS
cord-353633-a4pu6rlu	279	2	of	of	IN
cord-353633-a4pu6rlu	279	3	the	the	DT
cord-353633-a4pu6rlu	279	4	treatment	treatment	NN
cord-353633-a4pu6rlu	279	5	targets	target	NNS
cord-353633-a4pu6rlu	279	6	have	have	VBP
cord-353633-a4pu6rlu	279	7	been	be	VBN
cord-353633-a4pu6rlu	279	8	identified	identify	VBN
cord-353633-a4pu6rlu	279	9	by	by	IN
cord-353633-a4pu6rlu	279	10	animal	animal	NN
cord-353633-a4pu6rlu	279	11	studies	study	NNS
cord-353633-a4pu6rlu	279	12	supported	support	VBN
cord-353633-a4pu6rlu	279	13	by	by	IN
cord-353633-a4pu6rlu	279	14	human	human	JJ
cord-353633-a4pu6rlu	279	15	physiology	physiology	NN
cord-353633-a4pu6rlu	279	16	or	or	CC
cord-353633-a4pu6rlu	279	17	epidemiological	epidemiological	JJ
cord-353633-a4pu6rlu	279	18	studies	study	NNS
cord-353633-a4pu6rlu	279	19	.	.	.
cord-353633-a4pu6rlu	279	20	 	 	_SP
cord-353633-a4pu6rlu	280	1	Proteomics	proteomic	NNS
cord-353633-a4pu6rlu	280	2	have	have	VBP
cord-353633-a4pu6rlu	280	3	not	not	RB
cord-353633-a4pu6rlu	280	4	been	be	VBN
cord-353633-a4pu6rlu	280	5	widely	widely	RB
cord-353633-a4pu6rlu	280	6	used	use	VBN
cord-353633-a4pu6rlu	280	7	in	in	IN
cord-353633-a4pu6rlu	280	8	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	280	9	research	research	NN
cord-353633-a4pu6rlu	280	10	.	.	.
cord-353633-a4pu6rlu	281	1	The	the	DT
cord-353633-a4pu6rlu	281	2	proteins	protein	NNS
cord-353633-a4pu6rlu	281	3	and	and	CC
cord-353633-a4pu6rlu	281	4	signaling	signal	VBG
cord-353633-a4pu6rlu	281	5	pathways	pathway	NNS
cord-353633-a4pu6rlu	281	6	involved	involve	VBN
cord-353633-a4pu6rlu	281	7	in	in	IN
cord-353633-a4pu6rlu	281	8	the	the	DT
cord-353633-a4pu6rlu	281	9	pathophysiology	pathophysiology	NN
cord-353633-a4pu6rlu	281	10	of	of	IN
cord-353633-a4pu6rlu	281	11	the	the	DT
cord-353633-a4pu6rlu	281	12	disease	disease	NN
cord-353633-a4pu6rlu	281	13	have	have	VBP
cord-353633-a4pu6rlu	281	14	been	be	VBN
cord-353633-a4pu6rlu	281	15	almost	almost	RB
cord-353633-a4pu6rlu	281	16	exclusively	exclusively	RB
cord-353633-a4pu6rlu	281	17	identified	identify	VBN
cord-353633-a4pu6rlu	281	18	by	by	IN
cord-353633-a4pu6rlu	281	19	targeted	target	VBN
cord-353633-a4pu6rlu	281	20	"	"	``
cord-353633-a4pu6rlu	281	21	hypothesis	hypothesis	NN
cord-353633-a4pu6rlu	281	22	-	-	HYPH
cord-353633-a4pu6rlu	281	23	driven	drive	VBN
cord-353633-a4pu6rlu	281	24	"	"	''
cord-353633-a4pu6rlu	281	25	approaches	approach	NNS
cord-353633-a4pu6rlu	281	26	based	base	VBN
cord-353633-a4pu6rlu	281	27	on	on	IN
cord-353633-a4pu6rlu	281	28	data	datum	NNS
cord-353633-a4pu6rlu	281	29	from	from	IN
cord-353633-a4pu6rlu	281	30	mechanistic	mechanistic	JJ
cord-353633-a4pu6rlu	281	31	animal	animal	NN
cord-353633-a4pu6rlu	281	32	,	,	,
cord-353633-a4pu6rlu	281	33	observational	observational	JJ
cord-353633-a4pu6rlu	281	34	human	human	NN
cord-353633-a4pu6rlu	281	35	and	and	CC
cord-353633-a4pu6rlu	281	36	in	in	IN
cord-353633-a4pu6rlu	281	37	some	some	DT
cord-353633-a4pu6rlu	281	38	cases	case	NNS
cord-353633-a4pu6rlu	281	39	large	large	JJ
cord-353633-a4pu6rlu	281	40	epidemiological	epidemiological	JJ
cord-353633-a4pu6rlu	281	41	studies	study	NNS
cord-353633-a4pu6rlu	281	42	.	.	.
cord-353633-a4pu6rlu	282	1	This	this	DT
cord-353633-a4pu6rlu	282	2	is	be	VBZ
cord-353633-a4pu6rlu	282	3	probably	probably	RB
cord-353633-a4pu6rlu	282	4	due	due	JJ
cord-353633-a4pu6rlu	282	5	to	to	IN
cord-353633-a4pu6rlu	282	6	methodological	methodological	JJ
cord-353633-a4pu6rlu	282	7	challenges	challenge	NNS
cord-353633-a4pu6rlu	282	8	and	and	CC
cord-353633-a4pu6rlu	282	9	technical	technical	JJ
cord-353633-a4pu6rlu	282	10	limitations	limitation	NNS
cord-353633-a4pu6rlu	282	11	related	relate	VBN
cord-353633-a4pu6rlu	282	12	to	to	IN
cord-353633-a4pu6rlu	282	13	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	282	14	.	.	.
cord-353633-a4pu6rlu	283	1	We	-PRON-	PRP
cord-353633-a4pu6rlu	283	2	expect	expect	VBP
cord-353633-a4pu6rlu	283	3	in	in	IN
cord-353633-a4pu6rlu	283	4	the	the	DT
cord-353633-a4pu6rlu	283	5	near	near	JJ
cord-353633-a4pu6rlu	283	6	future	future	JJ
cord-353633-a4pu6rlu	283	7	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	283	8	to	to	TO
cord-353633-a4pu6rlu	283	9	be	be	VB
cord-353633-a4pu6rlu	283	10	much	much	RB
cord-353633-a4pu6rlu	283	11	more	more	RBR
cord-353633-a4pu6rlu	283	12	frequently	frequently	RB
cord-353633-a4pu6rlu	283	13	applied	apply	VBN
cord-353633-a4pu6rlu	283	14	in	in	IN
cord-353633-a4pu6rlu	283	15	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	283	16	studies	study	NNS
cord-353633-a4pu6rlu	283	17	.	.	.
cord-353633-a4pu6rlu	284	1	We	-PRON-	PRP
cord-353633-a4pu6rlu	284	2	expect	expect	VBP
cord-353633-a4pu6rlu	284	3	that	that	IN
cord-353633-a4pu6rlu	284	4	the	the	DT
cord-353633-a4pu6rlu	284	5	main	main	JJ
cord-353633-a4pu6rlu	284	6	contribution	contribution	NN
cord-353633-a4pu6rlu	284	7	of	of	IN
cord-353633-a4pu6rlu	284	8	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	284	9	will	will	MD
cord-353633-a4pu6rlu	284	10	not	not	RB
cord-353633-a4pu6rlu	284	11	be	be	VB
cord-353633-a4pu6rlu	284	12	in	in	IN
cord-353633-a4pu6rlu	284	13	direct	direct	JJ
cord-353633-a4pu6rlu	284	14	development	development	NN
cord-353633-a4pu6rlu	284	15	of	of	IN
cord-353633-a4pu6rlu	284	16	non	non	JJ
cord-353633-a4pu6rlu	284	17	-	-	JJ
cord-353633-a4pu6rlu	284	18	invasive	invasive	JJ
cord-353633-a4pu6rlu	284	19	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	284	20	scores	score	NNS
cord-353633-a4pu6rlu	284	21	but	but	CC
cord-353633-a4pu6rlu	284	22	rather	rather	RB
cord-353633-a4pu6rlu	284	23	in	in	IN
cord-353633-a4pu6rlu	284	24	the	the	DT
cord-353633-a4pu6rlu	284	25	identification	identification	NN
cord-353633-a4pu6rlu	284	26	of	of	IN
cord-353633-a4pu6rlu	284	27	novel	novel	NN
cord-353633-a4pu6rlu	284	28	molecules	molecule	NNS
cord-353633-a4pu6rlu	284	29	and/or	and/or	CC
cord-353633-a4pu6rlu	284	30	pathways	pathway	NNS
cord-353633-a4pu6rlu	284	31	with	with	IN
cord-353633-a4pu6rlu	284	32	important	important	JJ
cord-353633-a4pu6rlu	284	33	role	role	NN
cord-353633-a4pu6rlu	284	34	in	in	IN
cord-353633-a4pu6rlu	284	35	the	the	DT
cord-353633-a4pu6rlu	284	36	pathophysiology	pathophysiology	NN
cord-353633-a4pu6rlu	284	37	of	of	IN
cord-353633-a4pu6rlu	284	38	the	the	DT
cord-353633-a4pu6rlu	284	39	disease	disease	NN
cord-353633-a4pu6rlu	284	40	and	and	CC
cord-353633-a4pu6rlu	284	41	with	with	IN
cord-353633-a4pu6rlu	284	42	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	284	43	and	and	CC
cord-353633-a4pu6rlu	284	44	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	284	45	potentials	potential	NNS
cord-353633-a4pu6rlu	284	46	.	.	.
cord-353633-a4pu6rlu	285	1	Metabolomics	metabolomic	NNS
cord-353633-a4pu6rlu	285	2	refers	refer	VBZ
cord-353633-a4pu6rlu	285	3	to	to	IN
cord-353633-a4pu6rlu	285	4	the	the	DT
cord-353633-a4pu6rlu	285	5	investigation	investigation	NN
cord-353633-a4pu6rlu	285	6	of	of	IN
cord-353633-a4pu6rlu	285	7	small	small	JJ
cord-353633-a4pu6rlu	285	8	molecules	molecule	NNS
cord-353633-a4pu6rlu	285	9	and	and	CC
cord-353633-a4pu6rlu	285	10	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	285	11	products	product	NNS
cord-353633-a4pu6rlu	285	12	,	,	,
cord-353633-a4pu6rlu	285	13	such	such	JJ
cord-353633-a4pu6rlu	285	14	as	as	IN
cord-353633-a4pu6rlu	285	15	aminoacids	aminoacid	NNS
cord-353633-a4pu6rlu	285	16	,	,	,
cord-353633-a4pu6rlu	285	17	fatty	fatty	JJ
cord-353633-a4pu6rlu	285	18	acids	acid	NNS
cord-353633-a4pu6rlu	285	19	and	and	CC
cord-353633-a4pu6rlu	285	20	carbohydrates	carbohydrate	NNS
cord-353633-a4pu6rlu	285	21	.	.	.
cord-353633-a4pu6rlu	286	1	Lipidomics	lipidomic	NNS
cord-353633-a4pu6rlu	286	2	are	be	VBP
cord-353633-a4pu6rlu	286	3	J	J	NNP
cord-353633-a4pu6rlu	286	4	o	o	NN
cord-353633-a4pu6rlu	286	5	u	u	NN
cord-353633-a4pu6rlu	286	6	r	r	NN
cord-353633-a4pu6rlu	286	7	n	n	NN
cord-353633-a4pu6rlu	287	1	a	a	DT
cord-353633-a4pu6rlu	287	2	l	l	NN
cord-353633-a4pu6rlu	287	3	P	p	NN
cord-353633-a4pu6rlu	287	4	r	r	NN
cord-353633-a4pu6rlu	287	5	e	e	NN
cord-353633-a4pu6rlu	287	6	-p	-p	NN
cord-353633-a4pu6rlu	287	7	r	r	NN
cord-353633-a4pu6rlu	287	8	o	o	NN
cord-353633-a4pu6rlu	287	9	o	o	NN
cord-353633-a4pu6rlu	287	10	f	f	NN
cord-353633-a4pu6rlu	287	11	38	38	CD
cord-353633-a4pu6rlu	287	12	considered	consider	VBN
cord-353633-a4pu6rlu	287	13	part	part	NN
cord-353633-a4pu6rlu	287	14	of	of	IN
cord-353633-a4pu6rlu	287	15	metabolomics	metabolomic	NNS
cord-353633-a4pu6rlu	287	16	and	and	CC
cord-353633-a4pu6rlu	287	17	refer	refer	VB
cord-353633-a4pu6rlu	287	18	to	to	IN
cord-353633-a4pu6rlu	287	19	the	the	DT
cord-353633-a4pu6rlu	287	20	investigation	investigation	NN
cord-353633-a4pu6rlu	287	21	of	of	IN
cord-353633-a4pu6rlu	287	22	cellular	cellular	JJ
cord-353633-a4pu6rlu	287	23	lipids	lipid	NNS
cord-353633-a4pu6rlu	287	24	.	.	.
cord-353633-a4pu6rlu	288	1	Numerous	numerous	JJ
cord-353633-a4pu6rlu	288	2	studies	study	NNS
cord-353633-a4pu6rlu	288	3	have	have	VBP
cord-353633-a4pu6rlu	288	4	investigated	investigate	VBN
cord-353633-a4pu6rlu	288	5	the	the	DT
cord-353633-a4pu6rlu	288	6	metabolome	metabolome	NN
cord-353633-a4pu6rlu	288	7	and	and	CC
cord-353633-a4pu6rlu	288	8	lipidome	lipidome	NNP
cord-353633-a4pu6rlu	288	9	in	in	IN
cord-353633-a4pu6rlu	288	10	mouse	mouse	NN
cord-353633-a4pu6rlu	288	11	models	model	NNS
cord-353633-a4pu6rlu	288	12	or	or	CC
cord-353633-a4pu6rlu	288	13	patients	patient	NNS
cord-353633-a4pu6rlu	288	14	with	with	IN
cord-353633-a4pu6rlu	288	15	NASH	NASH	NNP
cord-353633-a4pu6rlu	288	16	.	.	.
cord-353633-a4pu6rlu	289	1	The	the	DT
cord-353633-a4pu6rlu	289	2	evidence	evidence	NN
cord-353633-a4pu6rlu	289	3	linking	link	VBG
cord-353633-a4pu6rlu	289	4	bile	bile	NN
cord-353633-a4pu6rlu	289	5	acid	acid	NN
cord-353633-a4pu6rlu	289	6	homeostasis	homeostasis	NN
cord-353633-a4pu6rlu	289	7	as	as	RB
cord-353633-a4pu6rlu	289	8	well	well	RB
cord-353633-a4pu6rlu	289	9	as	as	IN
cord-353633-a4pu6rlu	289	10	gut	gut	NN
cord-353633-a4pu6rlu	289	11	microbiome	microbiome	NN
cord-353633-a4pu6rlu	289	12	with	with	IN
cord-353633-a4pu6rlu	289	13	the	the	DT
cord-353633-a4pu6rlu	289	14	development	development	NN
cord-353633-a4pu6rlu	289	15	and	and	CC
cord-353633-a4pu6rlu	289	16	progress	progress	NN
cord-353633-a4pu6rlu	289	17	of	of	IN
cord-353633-a4pu6rlu	289	18	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	289	19	have	have	VBP
cord-353633-a4pu6rlu	289	20	been	be	VBN
cord-353633-a4pu6rlu	289	21	recently	recently	RB
cord-353633-a4pu6rlu	289	22	reviewed	review	VBN
cord-353633-a4pu6rlu	289	23	elsewhere	elsewhere	RB
cord-353633-a4pu6rlu	289	24	[	[	-LRB-
cord-353633-a4pu6rlu	289	25	156	156	CD
cord-353633-a4pu6rlu	289	26	,	,	,
cord-353633-a4pu6rlu	289	27	157	157	CD
cord-353633-a4pu6rlu	289	28	]	]	-RRB-
cord-353633-a4pu6rlu	289	29	.	.	.
cord-353633-a4pu6rlu	290	1	In	in	IN
cord-353633-a4pu6rlu	290	2	this	this	DT
cord-353633-a4pu6rlu	290	3	section	section	NN
cord-353633-a4pu6rlu	290	4	,	,	,
cord-353633-a4pu6rlu	290	5	we	-PRON-	PRP
cord-353633-a4pu6rlu	290	6	will	will	MD
cord-353633-a4pu6rlu	290	7	focus	focus	VB
cord-353633-a4pu6rlu	290	8	particularly	particularly	RB
cord-353633-a4pu6rlu	290	9	on	on	IN
cord-353633-a4pu6rlu	290	10	the	the	DT
cord-353633-a4pu6rlu	290	11	robust	robust	JJ
cord-353633-a4pu6rlu	290	12	and	and	CC
cord-353633-a4pu6rlu	290	13	extensive	extensive	JJ
cord-353633-a4pu6rlu	290	14	changes	change	NNS
cord-353633-a4pu6rlu	290	15	that	that	WDT
cord-353633-a4pu6rlu	290	16	are	be	VBP
cord-353633-a4pu6rlu	290	17	observed	observe	VBN
cord-353633-a4pu6rlu	290	18	both	both	CC
cord-353633-a4pu6rlu	290	19	in	in	IN
cord-353633-a4pu6rlu	290	20	the	the	DT
cord-353633-a4pu6rlu	290	21	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	290	22	(	(	-LRB-
cord-353633-a4pu6rlu	290	23	Figure	figure	NN
cord-353633-a4pu6rlu	290	24	3	3	CD
cord-353633-a4pu6rlu	290	25	)	)	-RRB-
cord-353633-a4pu6rlu	290	26	as	as	RB
cord-353633-a4pu6rlu	290	27	well	well	RB
cord-353633-a4pu6rlu	290	28	as	as	IN
cord-353633-a4pu6rlu	290	29	in	in	IN
cord-353633-a4pu6rlu	290	30	the	the	DT
cord-353633-a4pu6rlu	290	31	circulating	circulate	VBG
cord-353633-a4pu6rlu	290	32	lipidome	lipidome	NN
cord-353633-a4pu6rlu	290	33	,	,	,
cord-353633-a4pu6rlu	290	34	which	which	WDT
cord-353633-a4pu6rlu	290	35	have	have	VBP
cord-353633-a4pu6rlu	290	36	led	lead	VBN
cord-353633-a4pu6rlu	290	37	to	to	IN
cord-353633-a4pu6rlu	290	38	the	the	DT
cord-353633-a4pu6rlu	290	39	development	development	NN
cord-353633-a4pu6rlu	290	40	of	of	IN
cord-353633-a4pu6rlu	290	41	numerous	numerous	JJ
cord-353633-a4pu6rlu	290	42	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	290	43	models	model	NNS
cord-353633-a4pu6rlu	290	44	for	for	IN
cord-353633-a4pu6rlu	290	45	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	290	46	as	as	RB
cord-353633-a4pu6rlu	290	47	well	well	RB
cord-353633-a4pu6rlu	290	48	as	as	IN
cord-353633-a4pu6rlu	290	49	to	to	IN
cord-353633-a4pu6rlu	290	50	the	the	DT
cord-353633-a4pu6rlu	290	51	identification	identification	NN
cord-353633-a4pu6rlu	290	52	of	of	IN
cord-353633-a4pu6rlu	290	53	novel	novel	JJ
cord-353633-a4pu6rlu	290	54	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	290	55	targets	target	NNS
cord-353633-a4pu6rlu	290	56	.	.	.
cord-353633-a4pu6rlu	291	1	The	the	DT
cord-353633-a4pu6rlu	291	2	development	development	NN
cord-353633-a4pu6rlu	291	3	of	of	IN
cord-353633-a4pu6rlu	291	4	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	291	5	is	be	VBZ
cord-353633-a4pu6rlu	291	6	strongly	strongly	RB
cord-353633-a4pu6rlu	291	7	associated	associate	VBN
cord-353633-a4pu6rlu	291	8	with	with	IN
cord-353633-a4pu6rlu	291	9	obesity	obesity	NN
cord-353633-a4pu6rlu	291	10	and	and	CC
cord-353633-a4pu6rlu	291	11	is	be	VBZ
cord-353633-a4pu6rlu	291	12	characterized	characterize	VBN
cord-353633-a4pu6rlu	291	13	by	by	IN
cord-353633-a4pu6rlu	291	14	increased	increase	VBN
cord-353633-a4pu6rlu	291	15	lipid	lipid	NN
cord-353633-a4pu6rlu	291	16	accumulation	accumulation	NN
cord-353633-a4pu6rlu	291	17	due	due	IN
cord-353633-a4pu6rlu	291	18	to	to	IN
cord-353633-a4pu6rlu	291	19	higher	high	JJR
cord-353633-a4pu6rlu	291	20	uptake	uptake	NN
cord-353633-a4pu6rlu	291	21	of	of	IN
cord-353633-a4pu6rlu	291	22	elevated	elevated	JJ
cord-353633-a4pu6rlu	291	23	FFA	FFA	NNP
cord-353633-a4pu6rlu	291	24	by	by	IN
cord-353633-a4pu6rlu	291	25	unrestricted	unrestricted	JJ
cord-353633-a4pu6rlu	291	26	adipose	adipose	JJ
cord-353633-a4pu6rlu	291	27	tissue	tissue	NN
cord-353633-a4pu6rlu	291	28	lipolysis	lipolysis	NN
cord-353633-a4pu6rlu	291	29	and	and	CC
cord-353633-a4pu6rlu	291	30	due	due	IN
cord-353633-a4pu6rlu	291	31	to	to	IN
cord-353633-a4pu6rlu	291	32	increased	increase	VBN
cord-353633-a4pu6rlu	291	33	[	[	-LRB-
cord-353633-a4pu6rlu	291	34	164	164	CD
cord-353633-a4pu6rlu	291	35	]	]	-RRB-
cord-353633-a4pu6rlu	291	36	[	[	-LRB-
cord-353633-a4pu6rlu	291	37	165	165	CD
cord-353633-a4pu6rlu	291	38	]	]	-RRB-
cord-353633-a4pu6rlu	291	39	[	[	-LRB-
cord-353633-a4pu6rlu	291	40	166	166	CD
cord-353633-a4pu6rlu	291	41	]	]	-RRB-
cord-353633-a4pu6rlu	291	42	.	.	.
cord-353633-a4pu6rlu	292	1	In	in	IN
cord-353633-a4pu6rlu	292	2	non	non	JJ
cord-353633-a4pu6rlu	292	3	-	-	JJ
cord-353633-a4pu6rlu	292	4	parenchymal	parenchymal	JJ
cord-353633-a4pu6rlu	292	5	liver	liver	NN
cord-353633-a4pu6rlu	292	6	cells	cell	NNS
cord-353633-a4pu6rlu	292	7	,	,	,
cord-353633-a4pu6rlu	292	8	SFA	SFA	NNP
cord-353633-a4pu6rlu	292	9	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	292	10	the	the	DT
cord-353633-a4pu6rlu	292	11	production	production	NN
cord-353633-a4pu6rlu	292	12	and	and	CC
cord-353633-a4pu6rlu	292	13	secretion	secretion	NN
cord-353633-a4pu6rlu	292	14	of	of	IN
cord-353633-a4pu6rlu	292	15	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	292	16	and	and	CC
cord-353633-a4pu6rlu	292	17	profibrotic	profibrotic	JJ
cord-353633-a4pu6rlu	292	18	cytokines	cytokine	NNS
cord-353633-a4pu6rlu	292	19	from	from	IN
cord-353633-a4pu6rlu	292	20	Kupffer	Kupffer	NNP
cord-353633-a4pu6rlu	292	21	cells	cell	NNS
cord-353633-a4pu6rlu	292	22	and	and	CC
cord-353633-a4pu6rlu	292	23	induce	induce	VB
cord-353633-a4pu6rlu	292	24	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	292	25	M1	M1	NNP
cord-353633-a4pu6rlu	292	26	polarization	polarization	NN
cord-353633-a4pu6rlu	292	27	of	of	IN
cord-353633-a4pu6rlu	292	28	macrophages	macrophage	NNS
cord-353633-a4pu6rlu	292	29	[	[	-LRB-
cord-353633-a4pu6rlu	292	30	166	166	CD
cord-353633-a4pu6rlu	292	31	,	,	,
cord-353633-a4pu6rlu	292	32	167	167	CD
cord-353633-a4pu6rlu	292	33	]	]	-RRB-
cord-353633-a4pu6rlu	292	34	.	.	.
cord-353633-a4pu6rlu	293	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	293	2	,	,	,
cord-353633-a4pu6rlu	293	3	they	-PRON-	PRP
cord-353633-a4pu6rlu	293	4	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	293	5	the	the	DT
cord-353633-a4pu6rlu	293	6	secretion	secretion	NN
cord-353633-a4pu6rlu	293	7	of	of	IN
cord-353633-a4pu6rlu	293	8	chemokines	chemokine	NNS
cord-353633-a4pu6rlu	293	9	from	from	IN
cord-353633-a4pu6rlu	293	10	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	293	11	stellate	stellate	JJ
cord-353633-a4pu6rlu	293	12	cells	cell	NNS
cord-353633-a4pu6rlu	293	13	that	that	WDT
cord-353633-a4pu6rlu	293	14	recruit	recruit	VBP
cord-353633-a4pu6rlu	293	15	more	more	JJR
cord-353633-a4pu6rlu	293	16	macrophages	macrophage	NNS
cord-353633-a4pu6rlu	293	17	in	in	IN
cord-353633-a4pu6rlu	293	18	the	the	DT
cord-353633-a4pu6rlu	293	19	liver	liver	NN
cord-353633-a4pu6rlu	293	20	[	[	-LRB-
cord-353633-a4pu6rlu	293	21	166	166	CD
cord-353633-a4pu6rlu	293	22	,	,	,
cord-353633-a4pu6rlu	293	23	167	167	CD
cord-353633-a4pu6rlu	293	24	]	]	-RRB-
cord-353633-a4pu6rlu	293	25	.	.	.
cord-353633-a4pu6rlu	294	1	Similar	similar	JJ
cord-353633-a4pu6rlu	294	2	to	to	IN
cord-353633-a4pu6rlu	294	3	SFA	SFA	NNP
cord-353633-a4pu6rlu	294	4	,	,	,
cord-353633-a4pu6rlu	294	5	lysophosphatidylcholines	lysophosphatidylcholine	NNS
cord-353633-a4pu6rlu	294	6	(	(	-LRB-
cord-353633-a4pu6rlu	294	7	LPC	LPC	NNP
cord-353633-a4pu6rlu	294	8	)	)	-RRB-
cord-353633-a4pu6rlu	294	9	have	have	VBP
cord-353633-a4pu6rlu	294	10	unfavorable	unfavorable	JJ
cord-353633-a4pu6rlu	294	11	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	294	12	effects	effect	NNS
cord-353633-a4pu6rlu	294	13	.	.	.
cord-353633-a4pu6rlu	295	1	Specifically	specifically	RB
cord-353633-a4pu6rlu	295	2	,	,	,
cord-353633-a4pu6rlu	295	3	they	-PRON-	PRP
cord-353633-a4pu6rlu	295	4	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	295	5	ER	ER	NNP
cord-353633-a4pu6rlu	295	6	stress	stress	NN
cord-353633-a4pu6rlu	295	7	,	,	,
cord-353633-a4pu6rlu	295	8	cause	cause	VB
cord-353633-a4pu6rlu	295	9	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	295	10	dysfunction	dysfunction	NN
cord-353633-a4pu6rlu	295	11	and	and	CC
cord-353633-a4pu6rlu	295	12	increase	increase	NN
cord-353633-a4pu6rlu	295	13	apoptosis	apoptosis	NN
cord-353633-a4pu6rlu	295	14	[	[	-LRB-
cord-353633-a4pu6rlu	295	15	168	168	CD
cord-353633-a4pu6rlu	295	16	]	]	-RRB-
cord-353633-a4pu6rlu	295	17	.	.	.
cord-353633-a4pu6rlu	296	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	296	2	,	,	,
cord-353633-a4pu6rlu	296	3	they	-PRON-	PRP
cord-353633-a4pu6rlu	296	4	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	296	5	the	the	DT
cord-353633-a4pu6rlu	296	6	release	release	NN
cord-353633-a4pu6rlu	296	7	of	of	IN
cord-353633-a4pu6rlu	296	8	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	296	9	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	296	10	vesicles	vesicle	NNS
cord-353633-a4pu6rlu	296	11	from	from	IN
cord-353633-a4pu6rlu	296	12	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	296	13	that	that	WDT
cord-353633-a4pu6rlu	296	14	trigger	trigger	VBP
cord-353633-a4pu6rlu	296	15	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	296	16	procedures	procedure	NNS
cord-353633-a4pu6rlu	296	17	[	[	-LRB-
cord-353633-a4pu6rlu	296	18	169	169	CD
cord-353633-a4pu6rlu	296	19	]	]	-RRB-
cord-353633-a4pu6rlu	296	20	.	.	.
cord-353633-a4pu6rlu	297	1	Moreover	moreover	RB
cord-353633-a4pu6rlu	297	2	,	,	,
cord-353633-a4pu6rlu	297	3	the	the	DT
cord-353633-a4pu6rlu	297	4	increased	increased	JJ
cord-353633-a4pu6rlu	297	5	activity	activity	NN
cord-353633-a4pu6rlu	297	6	of	of	IN
cord-353633-a4pu6rlu	297	7	the	the	DT
cord-353633-a4pu6rlu	297	8	enzyme	enzyme	NN
cord-353633-a4pu6rlu	297	9	phospholipase	phospholipase	NN
cord-353633-a4pu6rlu	297	10	A2	A2	NNP
cord-353633-a4pu6rlu	297	11	(	(	-LRB-
cord-353633-a4pu6rlu	297	12	PLA2	PLA2	NNP
cord-353633-a4pu6rlu	297	13	)	)	-RRB-
cord-353633-a4pu6rlu	297	14	that	that	WDT
cord-353633-a4pu6rlu	297	15	catalyzes	catalyze	VBZ
cord-353633-a4pu6rlu	297	16	the	the	DT
cord-353633-a4pu6rlu	297	17	formation	formation	NN
cord-353633-a4pu6rlu	297	18	of	of	IN
cord-353633-a4pu6rlu	297	19	LPC	LPC	NNP
cord-353633-a4pu6rlu	297	20	from	from	IN
cord-353633-a4pu6rlu	297	21	PC	pc	NN
cord-353633-a4pu6rlu	297	22	,	,	,
cord-353633-a4pu6rlu	297	23	leads	lead	VBZ
cord-353633-a4pu6rlu	297	24	to	to	IN
cord-353633-a4pu6rlu	297	25	the	the	DT
cord-353633-a4pu6rlu	297	26	rapid	rapid	JJ
cord-353633-a4pu6rlu	297	27	depletion	depletion	NN
cord-353633-a4pu6rlu	297	28	of	of	IN
cord-353633-a4pu6rlu	297	29	PC	pc	NN
cord-353633-a4pu6rlu	297	30	which	which	WDT
cord-353633-a4pu6rlu	297	31	affects	affect	VBZ
cord-353633-a4pu6rlu	297	32	hepatocyte	hepatocyte	NN
cord-353633-a4pu6rlu	297	33	membrane	membrane	NN
cord-353633-a4pu6rlu	297	34	integrity	integrity	NN
cord-353633-a4pu6rlu	297	35	and	and	CC
cord-353633-a4pu6rlu	297	36	results	result	NNS
cord-353633-a4pu6rlu	297	37	in	in	IN
cord-353633-a4pu6rlu	297	38	hepatocyte	hepatocyte	NN
cord-353633-a4pu6rlu	297	39	apoptosis	apoptosis	NN
cord-353633-a4pu6rlu	297	40	,	,	,
cord-353633-a4pu6rlu	297	41	high	high	JJ
cord-353633-a4pu6rlu	297	42	release	release	NN
cord-353633-a4pu6rlu	297	43	of	of	IN
cord-353633-a4pu6rlu	297	44	lipotoxic	lipotoxic	JJ
cord-353633-a4pu6rlu	297	45	lipids	lipid	NNS
cord-353633-a4pu6rlu	297	46	and	and	CC
cord-353633-a4pu6rlu	297	47	increased	increase	VBN
cord-353633-a4pu6rlu	297	48	inflammation	inflammation	NN
cord-353633-a4pu6rlu	297	49	[	[	-LRB-
cord-353633-a4pu6rlu	297	50	170	170	CD
cord-353633-a4pu6rlu	297	51	]	]	-RRB-
cord-353633-a4pu6rlu	297	52	.	.	.
cord-353633-a4pu6rlu	298	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	298	2	,	,	,
cord-353633-a4pu6rlu	298	3	PC	pc	NN
cord-353633-a4pu6rlu	298	4	deficiency	deficiency	NN
cord-353633-a4pu6rlu	298	5	reduces	reduce	VBZ
cord-353633-a4pu6rlu	298	6	VLDL	VLDL	NNP
cord-353633-a4pu6rlu	298	7	secretion	secretion	NN
cord-353633-a4pu6rlu	298	8	resulting	result	VBG
cord-353633-a4pu6rlu	298	9	in	in	IN
cord-353633-a4pu6rlu	298	10	higher	high	JJR
cord-353633-a4pu6rlu	298	11	intrahepatic	intrahepatic	JJ
cord-353633-a4pu6rlu	298	12	lipid	lipid	NN
cord-353633-a4pu6rlu	298	13	degradation	degradation	NN
cord-353633-a4pu6rlu	298	14	and	and	CC
cord-353633-a4pu6rlu	298	15	formation	formation	NN
cord-353633-a4pu6rlu	298	16	of	of	IN
cord-353633-a4pu6rlu	298	17	toxic	toxic	JJ
cord-353633-a4pu6rlu	298	18	intermediates	intermediate	NNS
cord-353633-a4pu6rlu	298	19	.	.	.
cord-353633-a4pu6rlu	299	1	Furthermore	furthermore	RB
cord-353633-a4pu6rlu	299	2	,	,	,
cord-353633-a4pu6rlu	299	3	the	the	DT
cord-353633-a4pu6rlu	299	4	low	low	JJ
cord-353633-a4pu6rlu	299	5	PC	pc	NN
cord-353633-a4pu6rlu	299	6	/	/	SYM
cord-353633-a4pu6rlu	299	7	PE	pe	NN
cord-353633-a4pu6rlu	299	8	ratio	ratio	NN
cord-353633-a4pu6rlu	299	9	affects	affect	VBZ
cord-353633-a4pu6rlu	299	10	lipid	lipid	NN
cord-353633-a4pu6rlu	299	11	droplet	droplet	NN
cord-353633-a4pu6rlu	299	12	stability	stability	NN
cord-353633-a4pu6rlu	299	13	,	,	,
cord-353633-a4pu6rlu	299	14	leading	lead	VBG
cord-353633-a4pu6rlu	299	15	to	to	IN
cord-353633-a4pu6rlu	299	16	the	the	DT
cord-353633-a4pu6rlu	299	17	formation	formation	NN
cord-353633-a4pu6rlu	299	18	of	of	IN
cord-353633-a4pu6rlu	299	19	larger	large	JJR
cord-353633-a4pu6rlu	299	20	lipid	lipid	NN
cord-353633-a4pu6rlu	299	21	droplets	droplet	NNS
cord-353633-a4pu6rlu	299	22	.	.	.
cord-353633-a4pu6rlu	300	1	Finally	finally	RB
cord-353633-a4pu6rlu	300	2	,	,	,
cord-353633-a4pu6rlu	300	3	LPC	LPC	NNP
cord-353633-a4pu6rlu	300	4	is	be	VBZ
cord-353633-a4pu6rlu	300	5	metabolized	metabolize	VBN
cord-353633-a4pu6rlu	300	6	by	by	IN
cord-353633-a4pu6rlu	300	7	the	the	DT
cord-353633-a4pu6rlu	300	8	enzyme	enzyme	NN
cord-353633-a4pu6rlu	300	9	autotaxin	autotaxin	NNP
cord-353633-a4pu6rlu	300	10	to	to	IN
cord-353633-a4pu6rlu	300	11	phospholipid	phospholipid	NN
cord-353633-a4pu6rlu	300	12	lysophosphatidic	lysophosphatidic	NNP
cord-353633-a4pu6rlu	300	13	acid	acid	NN
cord-353633-a4pu6rlu	300	14	which	which	WDT
cord-353633-a4pu6rlu	300	15	stimulates	stimulate	VBZ
cord-353633-a4pu6rlu	300	16	liver	liver	NN
cord-353633-a4pu6rlu	300	17	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	300	18	and	and	CC
cord-353633-a4pu6rlu	300	19	development	development	NN
cord-353633-a4pu6rlu	300	20	of	of	IN
cord-353633-a4pu6rlu	300	21	HCC	HCC	NNP
cord-353633-a4pu6rlu	300	22	[	[	-LRB-
cord-353633-a4pu6rlu	300	23	171	171	CD
cord-353633-a4pu6rlu	300	24	]	]	-RRB-
cord-353633-a4pu6rlu	300	25	.	.	.
cord-353633-a4pu6rlu	301	1	Ceramides	ceramide	NNS
cord-353633-a4pu6rlu	301	2	are	be	VBP
cord-353633-a4pu6rlu	301	3	a	a	DT
cord-353633-a4pu6rlu	301	4	type	type	NN
cord-353633-a4pu6rlu	301	5	of	of	IN
cord-353633-a4pu6rlu	301	6	sphingolipids	sphingolipid	NNS
cord-353633-a4pu6rlu	301	7	whose	whose	WP$
cord-353633-a4pu6rlu	301	8	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	301	9	levels	level	NNS
cord-353633-a4pu6rlu	301	10	are	be	VBP
cord-353633-a4pu6rlu	301	11	increased	increase	VBN
cord-353633-a4pu6rlu	301	12	in	in	IN
cord-353633-a4pu6rlu	301	13	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	301	14	and	and	CC
cord-353633-a4pu6rlu	301	15	correlate	correlate	VBP
cord-353633-a4pu6rlu	301	16	positively	positively	RB
cord-353633-a4pu6rlu	301	17	with	with	IN
cord-353633-a4pu6rlu	301	18	disease	disease	NN
cord-353633-a4pu6rlu	301	19	severity	severity	NN
cord-353633-a4pu6rlu	301	20	[	[	-LRB-
cord-353633-a4pu6rlu	301	21	46	46	CD
cord-353633-a4pu6rlu	301	22	,	,	,
cord-353633-a4pu6rlu	301	23	[	[	-LRB-
cord-353633-a4pu6rlu	301	24	159	159	CD
cord-353633-a4pu6rlu	301	25	]	]	-RRB-
cord-353633-a4pu6rlu	301	26	[	[	-LRB-
cord-353633-a4pu6rlu	301	27	160	160	CD
cord-353633-a4pu6rlu	301	28	]	]	-RRB-
cord-353633-a4pu6rlu	301	29	[	[	-LRB-
cord-353633-a4pu6rlu	301	30	161	161	CD
cord-353633-a4pu6rlu	301	31	]	]	-RRB-
cord-353633-a4pu6rlu	301	32	[	[	-LRB-
cord-353633-a4pu6rlu	301	33	162	162	CD
cord-353633-a4pu6rlu	301	34	]	]	-RRB-
cord-353633-a4pu6rlu	301	35	[	[	-LRB-
cord-353633-a4pu6rlu	301	36	163	163	CD
cord-353633-a4pu6rlu	301	37	]	]	-RRB-
cord-353633-a4pu6rlu	301	38	.	.	.
cord-353633-a4pu6rlu	302	1	In	in	IN
cord-353633-a4pu6rlu	302	2	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	302	3	,	,	,
cord-353633-a4pu6rlu	302	4	ceramide	ceramide	NN
cord-353633-a4pu6rlu	302	5	promotes	promote	VBZ
cord-353633-a4pu6rlu	302	6	insulin	insulin	NN
cord-353633-a4pu6rlu	302	7	resistance	resistance	NN
cord-353633-a4pu6rlu	302	8	by	by	IN
cord-353633-a4pu6rlu	302	9	inhibiting	inhibit	VBG
cord-353633-a4pu6rlu	302	10	Akt	Akt	NNP
cord-353633-a4pu6rlu	302	11	-	-	HYPH
cord-353633-a4pu6rlu	302	12	mediated	mediate	VBN
cord-353633-a4pu6rlu	302	13	insulin	insulin	NN
cord-353633-a4pu6rlu	302	14	signaling	signaling	NN
cord-353633-a4pu6rlu	302	15	,	,	,
cord-353633-a4pu6rlu	302	16	impairs	impair	VBZ
cord-353633-a4pu6rlu	302	17	beta	beta	NN
cord-353633-a4pu6rlu	302	18	-	-	HYPH
cord-353633-a4pu6rlu	302	19	oxidation	oxidation	NN
cord-353633-a4pu6rlu	302	20	,	,	,
cord-353633-a4pu6rlu	302	21	induces	induce	VBZ
cord-353633-a4pu6rlu	302	22	ROS	ROS	NNP
cord-353633-a4pu6rlu	302	23	production	production	NN
cord-353633-a4pu6rlu	302	24	,	,	,
cord-353633-a4pu6rlu	302	25	ER	ER	NNP
cord-353633-a4pu6rlu	302	26	stress	stress	NN
cord-353633-a4pu6rlu	302	27	and	and	CC
cord-353633-a4pu6rlu	302	28	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	302	29	cytokine	cytokine	NN
cord-353633-a4pu6rlu	302	30	secretion	secretion	NN
cord-353633-a4pu6rlu	302	31	,	,	,
cord-353633-a4pu6rlu	302	32	enhances	enhance	VBZ
cord-353633-a4pu6rlu	302	33	de	de	FW
cord-353633-a4pu6rlu	302	34	novo	novo	NNP
cord-353633-a4pu6rlu	302	35	lipogenesis	lipogenesis	NNP
cord-353633-a4pu6rlu	302	36	,	,	,
cord-353633-a4pu6rlu	302	37	cholesterol	cholesterol	NN
cord-353633-a4pu6rlu	302	38	synthesis	synthesis	NN
cord-353633-a4pu6rlu	302	39	and	and	CC
cord-353633-a4pu6rlu	302	40	triglyceride	triglyceride	NN
cord-353633-a4pu6rlu	302	41	accumulation	accumulation	NN
cord-353633-a4pu6rlu	302	42	and	and	CC
cord-353633-a4pu6rlu	302	43	induces	induce	VBZ
cord-353633-a4pu6rlu	302	44	apoptosis	apoptosis	NN
cord-353633-a4pu6rlu	302	45	[	[	-LRB-
cord-353633-a4pu6rlu	302	46	164	164	CD
cord-353633-a4pu6rlu	302	47	,	,	,
cord-353633-a4pu6rlu	302	48	[	[	-LRB-
cord-353633-a4pu6rlu	302	49	172	172	CD
cord-353633-a4pu6rlu	302	50	]	]	-RRB-
cord-353633-a4pu6rlu	302	51	[	[	-LRB-
cord-353633-a4pu6rlu	302	52	173	173	CD
cord-353633-a4pu6rlu	302	53	]	]	-RRB-
cord-353633-a4pu6rlu	302	54	[	[	-LRB-
cord-353633-a4pu6rlu	302	55	174	174	CD
cord-353633-a4pu6rlu	302	56	]	]	-RRB-
cord-353633-a4pu6rlu	302	57	[	[	-LRB-
cord-353633-a4pu6rlu	302	58	175	175	CD
cord-353633-a4pu6rlu	302	59	]	]	-RRB-
cord-353633-a4pu6rlu	302	60	.	.	.
cord-353633-a4pu6rlu	303	1	Finally	finally	RB
cord-353633-a4pu6rlu	303	2	,	,	,
cord-353633-a4pu6rlu	303	3	ceramide	ceramide	NN
cord-353633-a4pu6rlu	303	4	stimulates	stimulate	VBZ
cord-353633-a4pu6rlu	303	5	fibrogenesis	fibrogenesis	NN
cord-353633-a4pu6rlu	303	6	and	and	CC
cord-353633-a4pu6rlu	303	7	angiogenesis	angiogenesis	NN
cord-353633-a4pu6rlu	303	8	by	by	IN
cord-353633-a4pu6rlu	303	9	increasing	increase	VBG
cord-353633-a4pu6rlu	303	10	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	303	11	matrix	matrix	NN
cord-353633-a4pu6rlu	303	12	deposition	deposition	NN
cord-353633-a4pu6rlu	303	13	and	and	CC
cord-353633-a4pu6rlu	303	14	secretion	secretion	NN
cord-353633-a4pu6rlu	303	15	of	of	IN
cord-353633-a4pu6rlu	303	16	pro	pro	JJ
cord-353633-a4pu6rlu	303	17	-	-	JJ
cord-353633-a4pu6rlu	303	18	angiogenic	angiogenic	JJ
cord-353633-a4pu6rlu	303	19	factors	factor	NNS
cord-353633-a4pu6rlu	303	20	by	by	IN
cord-353633-a4pu6rlu	303	21	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	303	22	stellate	stellate	JJ
cord-353633-a4pu6rlu	303	23	cells	cell	NNS
cord-353633-a4pu6rlu	303	24	[	[	-LRB-
cord-353633-a4pu6rlu	303	25	176	176	CD
cord-353633-a4pu6rlu	303	26	]	]	-RRB-
cord-353633-a4pu6rlu	303	27	.	.	.
cord-353633-a4pu6rlu	304	1	[	[	-LRB-
cord-353633-a4pu6rlu	304	2	159	159	CD
cord-353633-a4pu6rlu	304	3	,	,	,
cord-353633-a4pu6rlu	304	4	162	162	CD
cord-353633-a4pu6rlu	304	5	,	,	,
cord-353633-a4pu6rlu	304	6	163	163	CD
cord-353633-a4pu6rlu	304	7	]	]	-RRB-
cord-353633-a4pu6rlu	304	8	.	.	.
cord-353633-a4pu6rlu	305	1	The	the	DT
cord-353633-a4pu6rlu	305	2	increased	increase	VBN
cord-353633-a4pu6rlu	305	3	ω-6	ω-6	NN
cord-353633-a4pu6rlu	305	4	concentrations	concentration	NNS
cord-353633-a4pu6rlu	305	5	lead	lead	VBP
cord-353633-a4pu6rlu	305	6	to	to	IN
cord-353633-a4pu6rlu	305	7	the	the	DT
cord-353633-a4pu6rlu	305	8	synthesis	synthesis	NN
cord-353633-a4pu6rlu	305	9	of	of	IN
cord-353633-a4pu6rlu	305	10	eicosanoids	eicosanoid	NNS
cord-353633-a4pu6rlu	305	11	by	by	IN
cord-353633-a4pu6rlu	305	12	their	-PRON-	PRP$
cord-353633-a4pu6rlu	305	13	enzymatic	enzymatic	JJ
cord-353633-a4pu6rlu	305	14	oxidation	oxidation	NN
cord-353633-a4pu6rlu	305	15	(	(	-LRB-
cord-353633-a4pu6rlu	305	16	especially	especially	RB
cord-353633-a4pu6rlu	305	17	of	of	IN
cord-353633-a4pu6rlu	305	18	AA	AA	NNP
cord-353633-a4pu6rlu	305	19	but	but	CC
cord-353633-a4pu6rlu	305	20	also	also	RB
cord-353633-a4pu6rlu	305	21	of	of	IN
cord-353633-a4pu6rlu	305	22	EPA	EPA	NNP
cord-353633-a4pu6rlu	305	23	and	and	CC
cord-353633-a4pu6rlu	305	24	dihomo	dihomo	NNP
cord-353633-a4pu6rlu	305	25	-	-	HYPH
cord-353633-a4pu6rlu	305	26	γ	γ	NN
cord-353633-a4pu6rlu	305	27	-	-	HYPH
cord-353633-a4pu6rlu	305	28	linolenic	linolenic	NN
cord-353633-a4pu6rlu	305	29	acid	acid	NN
cord-353633-a4pu6rlu	305	30	)	)	-RRB-
cord-353633-a4pu6rlu	305	31	with	with	IN
cord-353633-a4pu6rlu	305	32	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	305	33	properties	property	NNS
cord-353633-a4pu6rlu	305	34	such	such	JJ
cord-353633-a4pu6rlu	305	35	as	as	IN
cord-353633-a4pu6rlu	305	36	prostanglandines	prostanglandine	NNS
cord-353633-a4pu6rlu	305	37	,	,	,
cord-353633-a4pu6rlu	305	38	thromboxanes	thromboxane	NNS
cord-353633-a4pu6rlu	305	39	and	and	CC
cord-353633-a4pu6rlu	305	40	leukotrienes	leukotriene	NNS
cord-353633-a4pu6rlu	305	41	which	which	WDT
cord-353633-a4pu6rlu	305	42	induce	induce	VBP
cord-353633-a4pu6rlu	305	43	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	305	44	inflammation	inflammation	NN
cord-353633-a4pu6rlu	305	45	.	.	.
cord-353633-a4pu6rlu	306	1	This	this	DT
cord-353633-a4pu6rlu	306	2	occurs	occur	VBZ
cord-353633-a4pu6rlu	306	3	in	in	IN
cord-353633-a4pu6rlu	306	4	expense	expense	NN
cord-353633-a4pu6rlu	306	5	of	of	IN
cord-353633-a4pu6rlu	306	6	the	the	DT
cord-353633-a4pu6rlu	306	7	synthesis	synthesis	NN
cord-353633-a4pu6rlu	306	8	of	of	IN
cord-353633-a4pu6rlu	306	9	SPMs	spm	NNS
cord-353633-a4pu6rlu	306	10	that	that	WDT
cord-353633-a4pu6rlu	306	11	mainly	mainly	RB
cord-353633-a4pu6rlu	306	12	act	act	VBP
cord-353633-a4pu6rlu	306	13	to	to	TO
cord-353633-a4pu6rlu	306	14	restore	restore	VB
cord-353633-a4pu6rlu	306	15	normal	normal	JJ
cord-353633-a4pu6rlu	306	16	cell	cell	NN
cord-353633-a4pu6rlu	306	17	function	function	NN
cord-353633-a4pu6rlu	306	18	and	and	CC
cord-353633-a4pu6rlu	306	19	thus	thus	RB
cord-353633-a4pu6rlu	306	20	reduce	reduce	VB
cord-353633-a4pu6rlu	306	21	chronic	chronic	JJ
cord-353633-a4pu6rlu	306	22	inflammation	inflammation	NN
cord-353633-a4pu6rlu	306	23	and	and	CC
cord-353633-a4pu6rlu	306	24	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	306	25	[	[	-LRB-
cord-353633-a4pu6rlu	306	26	178	178	CD
cord-353633-a4pu6rlu	306	27	,	,	,
cord-353633-a4pu6rlu	306	28	179	179	CD
cord-353633-a4pu6rlu	306	29	]	]	-RRB-
cord-353633-a4pu6rlu	306	30	.	.	.
cord-353633-a4pu6rlu	307	1	Finally	finally	RB
cord-353633-a4pu6rlu	307	2	,	,	,
cord-353633-a4pu6rlu	307	3	the	the	DT
cord-353633-a4pu6rlu	307	4	high	high	JJ
cord-353633-a4pu6rlu	307	5	ω-6	ω-6	NN
cord-353633-a4pu6rlu	307	6	to	to	IN
cord-353633-a4pu6rlu	307	7	ω-3	ω-3	CD
cord-353633-a4pu6rlu	307	8	ratio	ratio	NN
cord-353633-a4pu6rlu	307	9	is	be	VBZ
cord-353633-a4pu6rlu	307	10	associated	associate	VBN
cord-353633-a4pu6rlu	307	11	with	with	IN
cord-353633-a4pu6rlu	307	12	an	an	DT
cord-353633-a4pu6rlu	307	13	impaired	impaired	JJ
cord-353633-a4pu6rlu	307	14	FADS1	fads1	NN
cord-353633-a4pu6rlu	307	15	activity	activity	NN
cord-353633-a4pu6rlu	307	16	that	that	WDT
cord-353633-a4pu6rlu	307	17	can	can	MD
cord-353633-a4pu6rlu	307	18	affect	affect	VB
cord-353633-a4pu6rlu	307	19	cell	cell	NN
cord-353633-a4pu6rlu	307	20	membrane	membrane	NN
cord-353633-a4pu6rlu	307	21	phospholipid	phospholipid	NN
cord-353633-a4pu6rlu	307	22	composition	composition	NN
cord-353633-a4pu6rlu	307	23	resulting	result	VBG
cord-353633-a4pu6rlu	307	24	in	in	IN
cord-353633-a4pu6rlu	307	25	membrane	membrane	NN
cord-353633-a4pu6rlu	307	26	deficiency	deficiency	NN
cord-353633-a4pu6rlu	307	27	,	,	,
cord-353633-a4pu6rlu	307	28	cell	cell	NN
cord-353633-a4pu6rlu	307	29	necrosis	necrosis	NN
cord-353633-a4pu6rlu	307	30	and	and	CC
cord-353633-a4pu6rlu	307	31	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	307	32	deposition	deposition	NN
cord-353633-a4pu6rlu	307	33	of	of	IN
cord-353633-a4pu6rlu	307	34	lipotoxic	lipotoxic	NNP
cord-353633-a4pu6rlu	307	35	lipids	lipid	NNS
cord-353633-a4pu6rlu	307	36	that	that	WDT
cord-353633-a4pu6rlu	307	37	can	can	MD
cord-353633-a4pu6rlu	307	38	aggravate	aggravate	VB
cord-353633-a4pu6rlu	307	39	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	307	40	injury	injury	NN
cord-353633-a4pu6rlu	307	41	[	[	-LRB-
cord-353633-a4pu6rlu	307	42	162	162	CD
cord-353633-a4pu6rlu	307	43	,	,	,
cord-353633-a4pu6rlu	307	44	163	163	CD
cord-353633-a4pu6rlu	307	45	]	]	-RRB-
cord-353633-a4pu6rlu	307	46	.	.	.
cord-353633-a4pu6rlu	308	1	Many	many	JJ
cord-353633-a4pu6rlu	308	2	studies	study	NNS
cord-353633-a4pu6rlu	308	3	have	have	VBP
cord-353633-a4pu6rlu	308	4	reported	report	VBN
cord-353633-a4pu6rlu	308	5	several	several	JJ
cord-353633-a4pu6rlu	308	6	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	308	7	models	model	NNS
cord-353633-a4pu6rlu	308	8	based	base	VBN
cord-353633-a4pu6rlu	308	9	on	on	IN
cord-353633-a4pu6rlu	308	10	metabolomics	metabolomic	NNS
cord-353633-a4pu6rlu	308	11	,	,	,
cord-353633-a4pu6rlu	308	12	lipidomics	lipidomic	NNS
cord-353633-a4pu6rlu	308	13	alone	alone	RB
cord-353633-a4pu6rlu	308	14	or	or	CC
cord-353633-a4pu6rlu	308	15	combined	combine	VBN
cord-353633-a4pu6rlu	308	16	with	with	IN
cord-353633-a4pu6rlu	308	17	other	other	JJ
cord-353633-a4pu6rlu	308	18	biochemical	biochemical	JJ
cord-353633-a4pu6rlu	308	19	and	and	CC
cord-353633-a4pu6rlu	308	20	clinical	clinical	JJ
cord-353633-a4pu6rlu	308	21	parameters	parameter	NNS
cord-353633-a4pu6rlu	308	22	for	for	IN
cord-353633-a4pu6rlu	308	23	the	the	DT
cord-353633-a4pu6rlu	308	24	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	308	25	and	and	CC
cord-353633-a4pu6rlu	308	26	staging	staging	NN
cord-353633-a4pu6rlu	308	27	of	of	IN
cord-353633-a4pu6rlu	308	28	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	308	29	(	(	-LRB-
cord-353633-a4pu6rlu	308	30	Table	table	NN
cord-353633-a4pu6rlu	308	31	4	4	CD
cord-353633-a4pu6rlu	308	32	)	)	-RRB-
cord-353633-a4pu6rlu	308	33	.	.	.
cord-353633-a4pu6rlu	309	1	The	the	DT
cord-353633-a4pu6rlu	309	2	best	good	JJS
cord-353633-a4pu6rlu	309	3	studies	study	NNS
cord-353633-a4pu6rlu	309	4	use	use	VBP
cord-353633-a4pu6rlu	309	5	populations	population	NNS
cord-353633-a4pu6rlu	309	6	of	of	IN
cord-353633-a4pu6rlu	309	7	biopsy	biopsy	NN
cord-353633-a4pu6rlu	309	8	-	-	HYPH
cord-353633-a4pu6rlu	309	9	proven	prove	VBN
cord-353633-a4pu6rlu	309	10	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	309	11	to	to	TO
cord-353633-a4pu6rlu	309	12	create	create	VB
cord-353633-a4pu6rlu	309	13	non	non	JJ
cord-353633-a4pu6rlu	309	14	-	-	JJ
cord-353633-a4pu6rlu	309	15	invasive	invasive	JJ
cord-353633-a4pu6rlu	309	16	algorithms	algorithm	NNS
cord-353633-a4pu6rlu	309	17	based	base	VBN
cord-353633-a4pu6rlu	309	18	on	on	IN
cord-353633-a4pu6rlu	309	19	blood	blood	NN
cord-353633-a4pu6rlu	309	20	measurements	measurement	NNS
cord-353633-a4pu6rlu	309	21	.	.	.
cord-353633-a4pu6rlu	310	1	The	the	DT
cord-353633-a4pu6rlu	310	2	models	model	NNS
cord-353633-a4pu6rlu	310	3	aim	aim	VBP
cord-353633-a4pu6rlu	310	4	to	to	TO
cord-353633-a4pu6rlu	310	5	diagnose	diagnose	VB
cord-353633-a4pu6rlu	310	6	advanced	advanced	JJ
cord-353633-a4pu6rlu	310	7	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	310	8	(	(	-LRB-
cord-353633-a4pu6rlu	310	9	≥3	≥3	NNP
cord-353633-a4pu6rlu	310	10	)	)	-RRB-
cord-353633-a4pu6rlu	310	11	(	(	-LRB-
cord-353633-a4pu6rlu	310	12	in	in	IN
cord-353633-a4pu6rlu	310	13	most	most	JJS
cord-353633-a4pu6rlu	310	14	studies	study	NNS
cord-353633-a4pu6rlu	310	15	)	)	-RRB-
cord-353633-a4pu6rlu	310	16	,	,	,
cord-353633-a4pu6rlu	310	17	differentiate	differentiate	VB
cord-353633-a4pu6rlu	310	18	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	310	19	from	from	IN
cord-353633-a4pu6rlu	310	20	healthy	healthy	JJ
cord-353633-a4pu6rlu	310	21	status	status	NN
cord-353633-a4pu6rlu	310	22	,	,	,
cord-353633-a4pu6rlu	310	23	distinguish	distinguish	VB
cord-353633-a4pu6rlu	310	24	between	between	IN
cord-353633-a4pu6rlu	310	25	NASH	NASH	NNP
cord-353633-a4pu6rlu	310	26	and	and	CC
cord-353633-a4pu6rlu	310	27	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	310	28	or	or	CC
cord-353633-a4pu6rlu	310	29	NASH	NASH	NNP
cord-353633-a4pu6rlu	310	30	vs	vs	IN
cord-353633-a4pu6rlu	310	31	non	non	NNP
cord-353633-a4pu6rlu	310	32	-	-	NNP
cord-353633-a4pu6rlu	310	33	NASH	NASH	NNP
cord-353633-a4pu6rlu	310	34	(	(	-LRB-
cord-353633-a4pu6rlu	310	35	in	in	IN
cord-353633-a4pu6rlu	310	36	many	many	JJ
cord-353633-a4pu6rlu	310	37	studies	study	NNS
cord-353633-a4pu6rlu	310	38	)	)	-RRB-
cord-353633-a4pu6rlu	310	39	,	,	,
cord-353633-a4pu6rlu	310	40	or	or	CC
cord-353633-a4pu6rlu	310	41	detect	detect	VB
cord-353633-a4pu6rlu	310	42	the	the	DT
cord-353633-a4pu6rlu	310	43	presence	presence	NN
cord-353633-a4pu6rlu	310	44	of	of	IN
cord-353633-a4pu6rlu	310	45	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	310	46	independently	independently	RB
cord-353633-a4pu6rlu	310	47	of	of	IN
cord-353633-a4pu6rlu	310	48	its	-PRON-	PRP$
cord-353633-a4pu6rlu	310	49	stage	stage	NN
cord-353633-a4pu6rlu	310	50	(	(	-LRB-
cord-353633-a4pu6rlu	310	51	in	in	IN
cord-353633-a4pu6rlu	310	52	few	few	JJ
cord-353633-a4pu6rlu	310	53	studies	study	NNS
cord-353633-a4pu6rlu	310	54	)	)	-RRB-
cord-353633-a4pu6rlu	310	55	.	.	.
cord-353633-a4pu6rlu	311	1	Challenges	challenge	NNS
cord-353633-a4pu6rlu	311	2	related	relate	VBN
cord-353633-a4pu6rlu	311	3	to	to	IN
cord-353633-a4pu6rlu	311	4	the	the	DT
cord-353633-a4pu6rlu	311	5	development	development	NN
cord-353633-a4pu6rlu	311	6	of	of	IN
cord-353633-a4pu6rlu	311	7	these	these	DT
cord-353633-a4pu6rlu	311	8	models	model	NNS
cord-353633-a4pu6rlu	311	9	are	be	VBP
cord-353633-a4pu6rlu	311	10	[	[	-LRB-
cord-353633-a4pu6rlu	311	11	180	180	CD
cord-353633-a4pu6rlu	311	12	]	]	-RRB-
cord-353633-a4pu6rlu	311	13	.	.	.
cord-353633-a4pu6rlu	312	1	Based	base	VBN
cord-353633-a4pu6rlu	312	2	on	on	IN
cord-353633-a4pu6rlu	312	3	the	the	DT
cord-353633-a4pu6rlu	312	4	above	above	JJ
cord-353633-a4pu6rlu	312	5	findings	finding	NNS
cord-353633-a4pu6rlu	312	6	and	and	CC
cord-353633-a4pu6rlu	312	7	methodology	methodology	NN
cord-353633-a4pu6rlu	312	8	,	,	,
cord-353633-a4pu6rlu	312	9	the	the	DT
cord-353633-a4pu6rlu	312	10	OWLiver	OWLiver	NNP
cord-353633-a4pu6rlu	312	11	®	®	POS
cord-353633-a4pu6rlu	312	12	test	test	NN
cord-353633-a4pu6rlu	312	13	was	be	VBD
cord-353633-a4pu6rlu	312	14	created	create	VBN
cord-353633-a4pu6rlu	312	15	,	,	,
cord-353633-a4pu6rlu	312	16	which	which	WDT
cord-353633-a4pu6rlu	312	17	includes	include	VBZ
cord-353633-a4pu6rlu	312	18	25	25	CD
cord-353633-a4pu6rlu	312	19	triglycerides	triglyceride	NNS
cord-353633-a4pu6rlu	312	20	and	and	CC
cord-353633-a4pu6rlu	312	21	aims	aim	VBZ
cord-353633-a4pu6rlu	312	22	to	to	TO
cord-353633-a4pu6rlu	312	23	discriminate	discriminate	VB
cord-353633-a4pu6rlu	312	24	NASH	NASH	NNP
cord-353633-a4pu6rlu	312	25	from	from	IN
cord-353633-a4pu6rlu	312	26	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	312	27	patients	patient	NNS
cord-353633-a4pu6rlu	312	28	.	.	.
cord-353633-a4pu6rlu	313	1	The	the	DT
cord-353633-a4pu6rlu	313	2	test	test	NN
cord-353633-a4pu6rlu	313	3	,	,	,
cord-353633-a4pu6rlu	313	4	which	which	WDT
cord-353633-a4pu6rlu	313	5	was	be	VBD
cord-353633-a4pu6rlu	313	6	initially	initially	RB
cord-353633-a4pu6rlu	313	7	trained	train	VBN
cord-353633-a4pu6rlu	313	8	in	in	IN
cord-353633-a4pu6rlu	313	9	white	white	JJ
cord-353633-a4pu6rlu	313	10	patients	patient	NNS
cord-353633-a4pu6rlu	313	11	without	without	IN
cord-353633-a4pu6rlu	313	12	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	313	13	,	,	,
cord-353633-a4pu6rlu	313	14	performed	perform	VBD
cord-353633-a4pu6rlu	313	15	poorly	poorly	RB
cord-353633-a4pu6rlu	313	16	in	in	IN
cord-353633-a4pu6rlu	313	17	a	a	DT
cord-353633-a4pu6rlu	313	18	multiethnic	multiethnic	JJ
cord-353633-a4pu6rlu	313	19	cohort	cohort	NN
cord-353633-a4pu6rlu	313	20	of	of	IN
cord-353633-a4pu6rlu	313	21	patients	patient	NNS
cord-353633-a4pu6rlu	313	22	with	with	IN
cord-353633-a4pu6rlu	313	23	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	313	24	(	(	-LRB-
cord-353633-a4pu6rlu	313	25	AUROC=0.69	AUROC=0.69	NNP
cord-353633-a4pu6rlu	313	26	)	)	-RRB-
cord-353633-a4pu6rlu	313	27	.	.	.
cord-353633-a4pu6rlu	314	1	This	this	DT
cord-353633-a4pu6rlu	314	2	shows	show	VBZ
cord-353633-a4pu6rlu	314	3	that	that	DT
cord-353633-a4pu6rlu	314	4	patient	patient	JJ
cord-353633-a4pu6rlu	314	5	heterogeneity	heterogeneity	NN
cord-353633-a4pu6rlu	314	6	is	be	VBZ
cord-353633-a4pu6rlu	314	7	an	an	DT
cord-353633-a4pu6rlu	314	8	important	important	JJ
cord-353633-a4pu6rlu	314	9	factor	factor	NN
cord-353633-a4pu6rlu	314	10	and	and	CC
cord-353633-a4pu6rlu	314	11	that	that	IN
cord-353633-a4pu6rlu	314	12	tests	test	NNS
cord-353633-a4pu6rlu	314	13	developed	develop	VBN
cord-353633-a4pu6rlu	314	14	in	in	IN
cord-353633-a4pu6rlu	314	15	non	non	JJ
cord-353633-a4pu6rlu	314	16	-	-	JJ
cord-353633-a4pu6rlu	314	17	diabetic	diabetic	JJ
cord-353633-a4pu6rlu	314	18	populations	population	NNS
cord-353633-a4pu6rlu	314	19	may	may	MD
cord-353633-a4pu6rlu	314	20	not	not	RB
cord-353633-a4pu6rlu	314	21	be	be	VB
cord-353633-a4pu6rlu	314	22	as	as	RB
cord-353633-a4pu6rlu	314	23	accurate	accurate	JJ
cord-353633-a4pu6rlu	314	24	in	in	IN
cord-353633-a4pu6rlu	314	25	patients	patient	NNS
cord-353633-a4pu6rlu	314	26	with	with	IN
cord-353633-a4pu6rlu	314	27	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	314	28	[	[	-LRB-
cord-353633-a4pu6rlu	314	29	181	181	CD
cord-353633-a4pu6rlu	314	30	]	]	-RRB-
cord-353633-a4pu6rlu	314	31	.	.	.
cord-353633-a4pu6rlu	315	1	In	in	IN
cord-353633-a4pu6rlu	315	2	another	another	DT
cord-353633-a4pu6rlu	315	3	study	study	NN
cord-353633-a4pu6rlu	315	4	,	,	,
cord-353633-a4pu6rlu	315	5	information	information	NN
cord-353633-a4pu6rlu	315	6	from	from	IN
cord-353633-a4pu6rlu	315	7	metabolomics	metabolomic	NNS
cord-353633-a4pu6rlu	315	8	and	and	CC
cord-353633-a4pu6rlu	315	9	lipidomics	lipidomic	NNS
cord-353633-a4pu6rlu	315	10	were	be	VBD
cord-353633-a4pu6rlu	315	11	combined	combine	VBN
cord-353633-a4pu6rlu	315	12	with	with	IN
cord-353633-a4pu6rlu	315	13	biochemical	biochemical	JJ
cord-353633-a4pu6rlu	315	14	and	and	CC
cord-353633-a4pu6rlu	315	15	genotypic	genotypic	JJ
cord-353633-a4pu6rlu	315	16	measurements	measurement	NNS
cord-353633-a4pu6rlu	315	17	to	to	TO
cord-353633-a4pu6rlu	315	18	create	create	VB
cord-353633-a4pu6rlu	315	19	an	an	DT
cord-353633-a4pu6rlu	315	20	algorithm	algorithm	NN
cord-353633-a4pu6rlu	315	21	for	for	IN
cord-353633-a4pu6rlu	315	22	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	315	23	NASH	NASH	NNP
cord-353633-a4pu6rlu	315	24	from	from	IN
cord-353633-a4pu6rlu	315	25	non	non	JJ
cord-353633-a4pu6rlu	315	26	-	-	JJ
cord-353633-a4pu6rlu	315	27	NASH	NASH	NNP
cord-353633-a4pu6rlu	315	28	(	(	-LRB-
cord-353633-a4pu6rlu	315	29	i.e.	i.e.	FW
cord-353633-a4pu6rlu	315	30	combined	combine	VBN
cord-353633-a4pu6rlu	315	31	healthy	healthy	JJ
cord-353633-a4pu6rlu	315	32	and	and	CC
cord-353633-a4pu6rlu	315	33	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	315	34	)	)	-RRB-
cord-353633-a4pu6rlu	315	35	.	.	.
cord-353633-a4pu6rlu	316	1	223	223	CD
cord-353633-a4pu6rlu	316	2	subjects	subject	NNS
cord-353633-a4pu6rlu	316	3	were	be	VBD
cord-353633-a4pu6rlu	316	4	used	use	VBN
cord-353633-a4pu6rlu	316	5	to	to	TO
cord-353633-a4pu6rlu	316	6	train	train	VB
cord-353633-a4pu6rlu	316	7	the	the	DT
cord-353633-a4pu6rlu	316	8	algorithm	algorithm	NN
cord-353633-a4pu6rlu	316	9	and	and	CC
cord-353633-a4pu6rlu	316	10	95	95	CD
cord-353633-a4pu6rlu	316	11	to	to	TO
cord-353633-a4pu6rlu	316	12	validate	validate	VB
cord-353633-a4pu6rlu	316	13	it	-PRON-	PRP
cord-353633-a4pu6rlu	316	14	.	.	.
cord-353633-a4pu6rlu	317	1	The	the	DT
cord-353633-a4pu6rlu	317	2	final	final	JJ
cord-353633-a4pu6rlu	317	3	model	model	NN
cord-353633-a4pu6rlu	317	4	consisted	consist	VBD
cord-353633-a4pu6rlu	317	5	of	of	IN
cord-353633-a4pu6rlu	317	6	AST	AST	NNP
cord-353633-a4pu6rlu	317	7	,	,	,
cord-353633-a4pu6rlu	317	8	insulin	insulin	NN
cord-353633-a4pu6rlu	317	9	,	,	,
cord-353633-a4pu6rlu	317	10	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	317	11	genotype	genotype	NN
cord-353633-a4pu6rlu	317	12	,	,	,
cord-353633-a4pu6rlu	317	13	glutamate	glutamate	NN
cord-353633-a4pu6rlu	317	14	,	,	,
cord-353633-a4pu6rlu	317	15	two	two	CD
cord-353633-a4pu6rlu	317	16	aminoacids	aminoacid	NNS
cord-353633-a4pu6rlu	317	17	(	(	-LRB-
cord-353633-a4pu6rlu	317	18	glycine	glycine	NN
cord-353633-a4pu6rlu	317	19	and	and	CC
cord-353633-a4pu6rlu	317	20	isoleucine	isoleucine	NNP
cord-353633-a4pu6rlu	317	21	)	)	-RRB-
cord-353633-a4pu6rlu	317	22	and	and	CC
cord-353633-a4pu6rlu	317	23	two	two	CD
cord-353633-a4pu6rlu	317	24	lipids	lipid	NNS
cord-353633-a4pu6rlu	317	25	(	(	-LRB-
cord-353633-a4pu6rlu	317	26	LysoPC	LysoPC	NNP
cord-353633-a4pu6rlu	317	27	16:0	16:0	CD
cord-353633-a4pu6rlu	317	28	and	and	CC
cord-353633-a4pu6rlu	317	29	PE	PE	NNP
cord-353633-a4pu6rlu	317	30	40:6	40:6	CD
cord-353633-a4pu6rlu	317	31	)	)	-RRB-
cord-353633-a4pu6rlu	317	32	and	and	CC
cord-353633-a4pu6rlu	317	33	was	be	VBD
cord-353633-a4pu6rlu	317	34	able	able	JJ
cord-353633-a4pu6rlu	317	35	to	to	TO
cord-353633-a4pu6rlu	317	36	differentiate	differentiate	VB
cord-353633-a4pu6rlu	317	37	NASH	NASH	NNP
cord-353633-a4pu6rlu	317	38	from	from	IN
cord-353633-a4pu6rlu	317	39	non	non	JJ
cord-353633-a4pu6rlu	317	40	-	-	JJ
cord-353633-a4pu6rlu	317	41	NASH	NASH	NNP
cord-353633-a4pu6rlu	317	42	with	with	IN
cord-353633-a4pu6rlu	317	43	85	85	CD
cord-353633-a4pu6rlu	317	44	%	%	NN
cord-353633-a4pu6rlu	317	45	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	317	46	and	and	CC
cord-353633-a4pu6rlu	317	47	72	72	CD
cord-353633-a4pu6rlu	317	48	%	%	NN
cord-353633-a4pu6rlu	317	49	specificity	specificity	NN
cord-353633-a4pu6rlu	317	50	[	[	-LRB-
cord-353633-a4pu6rlu	317	51	46	46	CD
cord-353633-a4pu6rlu	317	52	]	]	-RRB-
cord-353633-a4pu6rlu	318	1	.However	.However	.
cord-353633-a4pu6rlu	319	1	,	,	,
cord-353633-a4pu6rlu	319	2	the	the	DT
cord-353633-a4pu6rlu	319	3	non	non	JJ
cord-353633-a4pu6rlu	319	4	-	-	JJ
cord-353633-a4pu6rlu	319	5	NASH	NASH	NNP
cord-353633-a4pu6rlu	319	6	population	population	NN
cord-353633-a4pu6rlu	319	7	consisted	consist	VBD
cord-353633-a4pu6rlu	319	8	both	both	DT
cord-353633-a4pu6rlu	319	9	of	of	IN
cord-353633-a4pu6rlu	319	10	healthy	healthy	JJ
cord-353633-a4pu6rlu	319	11	subjects	subject	NNS
cord-353633-a4pu6rlu	319	12	(	(	-LRB-
cord-353633-a4pu6rlu	319	13	53	53	CD
cord-353633-a4pu6rlu	319	14	%	%	NN
cord-353633-a4pu6rlu	319	15	)	)	-RRB-
cord-353633-a4pu6rlu	319	16	and	and	CC
cord-353633-a4pu6rlu	319	17	of	of	IN
cord-353633-a4pu6rlu	319	18	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	319	19	(	(	-LRB-
cord-353633-a4pu6rlu	319	20	47	47	CD
cord-353633-a4pu6rlu	319	21	%	%	NN
cord-353633-a4pu6rlu	319	22	)	)	-RRB-
cord-353633-a4pu6rlu	319	23	.	.	.
cord-353633-a4pu6rlu	320	1	It	-PRON-	PRP
cord-353633-a4pu6rlu	320	2	is	be	VBZ
cord-353633-a4pu6rlu	320	3	though	though	IN
cord-353633-a4pu6rlu	320	4	important	important	JJ
cord-353633-a4pu6rlu	320	5	to	to	TO
cord-353633-a4pu6rlu	320	6	be	be	VB
cord-353633-a4pu6rlu	320	7	able	able	JJ
cord-353633-a4pu6rlu	320	8	to	to	TO
cord-353633-a4pu6rlu	320	9	distinguish	distinguish	VB
cord-353633-a4pu6rlu	320	10	accurately	accurately	RB
cord-353633-a4pu6rlu	320	11	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	320	12	from	from	IN
cord-353633-a4pu6rlu	320	13	healthy	healthy	JJ
cord-353633-a4pu6rlu	320	14	status	status	NN
cord-353633-a4pu6rlu	320	15	.	.	.
cord-353633-a4pu6rlu	321	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	321	2	,	,	,
cord-353633-a4pu6rlu	321	3	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	321	4	and	and	CC
cord-353633-a4pu6rlu	321	5	specificity	specificity	NN
cord-353633-a4pu6rlu	321	6	in	in	IN
cord-353633-a4pu6rlu	321	7	most	most	JJS
cord-353633-a4pu6rlu	321	8	tests	test	NNS
cord-353633-a4pu6rlu	321	9	is	be	VBZ
cord-353633-a4pu6rlu	321	10	high	high	JJ
cord-353633-a4pu6rlu	321	11	when	when	WRB
cord-353633-a4pu6rlu	321	12	healthy	healthy	JJ
cord-353633-a4pu6rlu	321	13	subjects	subject	NNS
cord-353633-a4pu6rlu	321	14	are	be	VBP
cord-353633-a4pu6rlu	321	15	included	include	VBN
cord-353633-a4pu6rlu	321	16	,	,	,
cord-353633-a4pu6rlu	321	17	but	but	CC
cord-353633-a4pu6rlu	321	18	the	the	DT
cord-353633-a4pu6rlu	321	19	same	same	JJ
cord-353633-a4pu6rlu	321	20	tests	test	NNS
cord-353633-a4pu6rlu	321	21	may	may	MD
cord-353633-a4pu6rlu	321	22	not	not	RB
cord-353633-a4pu6rlu	321	23	perform	perform	VB
cord-353633-a4pu6rlu	321	24	as	as	RB
cord-353633-a4pu6rlu	321	25	well	well	RB
cord-353633-a4pu6rlu	321	26	when	when	WRB
cord-353633-a4pu6rlu	321	27	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	321	28	is	be	VBZ
cord-353633-a4pu6rlu	321	29	directly	directly	RB
cord-353633-a4pu6rlu	321	30	compared	compare	VBN
cord-353633-a4pu6rlu	321	31	with	with	IN
cord-353633-a4pu6rlu	321	32	NASH	NASH	NNP
cord-353633-a4pu6rlu	321	33	.	.	.
cord-353633-a4pu6rlu	322	1	In	in	IN
cord-353633-a4pu6rlu	322	2	a	a	DT
cord-353633-a4pu6rlu	322	3	smaller	small	JJR
cord-353633-a4pu6rlu	322	4	proof	proof	NN
cord-353633-a4pu6rlu	322	5	-	-	HYPH
cord-353633-a4pu6rlu	322	6	of	of	IN
cord-353633-a4pu6rlu	322	7	-	-	HYPH
cord-353633-a4pu6rlu	322	8	concept	concept	NN
cord-353633-a4pu6rlu	322	9	study	study	NN
cord-353633-a4pu6rlu	322	10	a	a	DT
cord-353633-a4pu6rlu	322	11	different	different	JJ
cord-353633-a4pu6rlu	322	12	approach	approach	NN
cord-353633-a4pu6rlu	322	13	was	be	VBD
cord-353633-a4pu6rlu	322	14	followed	follow	VBN
cord-353633-a4pu6rlu	322	15	.	.	.
cord-353633-a4pu6rlu	323	1	A	a	DT
cord-353633-a4pu6rlu	323	2	lipidomics	lipidomic	NNS
cord-353633-a4pu6rlu	323	3	,	,	,
cord-353633-a4pu6rlu	323	4	glycomics	glycomic	NNS
cord-353633-a4pu6rlu	323	5	and	and	CC
cord-353633-a4pu6rlu	323	6	targeted	target	VBN
cord-353633-a4pu6rlu	323	7	hormonal	hormonal	JJ
cord-353633-a4pu6rlu	323	8	analysis	analysis	NN
cord-353633-a4pu6rlu	323	9	was	be	VBD
cord-353633-a4pu6rlu	323	10	performed	perform	VBN
cord-353633-a4pu6rlu	323	11	.	.	.
cord-353633-a4pu6rlu	324	1	Results	result	NNS
cord-353633-a4pu6rlu	324	2	were	be	VBD
cord-353633-a4pu6rlu	324	3	analyzed	analyze	VBN
cord-353633-a4pu6rlu	324	4	with	with	IN
cord-353633-a4pu6rlu	324	5	different	different	JJ
cord-353633-a4pu6rlu	324	6	machine	machine	NN
cord-353633-a4pu6rlu	324	7	learning	learn	VBG
cord-353633-a4pu6rlu	324	8	methods	method	NNS
cord-353633-a4pu6rlu	324	9	and	and	CC
cord-353633-a4pu6rlu	324	10	19	19	CD
cord-353633-a4pu6rlu	324	11	different	different	JJ
cord-353633-a4pu6rlu	324	12	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	324	13	models	model	NNS
cord-353633-a4pu6rlu	324	14	were	be	VBD
cord-353633-a4pu6rlu	324	15	reported	report	VBN
cord-353633-a4pu6rlu	324	16	for	for	IN
cord-353633-a4pu6rlu	324	17	classifying	classify	VBG
cord-353633-a4pu6rlu	324	18	the	the	DT
cord-353633-a4pu6rlu	324	19	subjects	subject	NNS
cord-353633-a4pu6rlu	324	20	simultaneously	simultaneously	RB
cord-353633-a4pu6rlu	324	21	to	to	IN
cord-353633-a4pu6rlu	324	22	healthy	healthy	JJ
cord-353633-a4pu6rlu	324	23	or	or	CC
cord-353633-a4pu6rlu	324	24	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	324	25	or	or	CC
cord-353633-a4pu6rlu	324	26	NASH	NASH	NNP
cord-353633-a4pu6rlu	324	27	group	group	NN
cord-353633-a4pu6rlu	324	28	.	.	.
cord-353633-a4pu6rlu	325	1	The	the	DT
cord-353633-a4pu6rlu	325	2	models	model	NNS
cord-353633-a4pu6rlu	325	3	consisted	consist	VBD
cord-353633-a4pu6rlu	325	4	of	of	IN
cord-353633-a4pu6rlu	325	5	varying	vary	VBG
cord-353633-a4pu6rlu	325	6	number	number	NN
cord-353633-a4pu6rlu	325	7	of	of	IN
cord-353633-a4pu6rlu	325	8	J	J	NNP
cord-353633-a4pu6rlu	325	9	o	o	NNP
cord-353633-a4pu6rlu	325	10	u	u	NN
cord-353633-a4pu6rlu	325	11	r	r	NNP
cord-353633-a4pu6rlu	325	12	n	n	NN
cord-353633-a4pu6rlu	325	13	a	a	DT
cord-353633-a4pu6rlu	325	14	l	l	NN
cord-353633-a4pu6rlu	325	15	P	p	NN
cord-353633-a4pu6rlu	325	16	r	r	NN
cord-353633-a4pu6rlu	325	17	e	e	NN
cord-353633-a4pu6rlu	326	1	-p	-p	:
cord-353633-a4pu6rlu	327	1	r	r	NN
cord-353633-a4pu6rlu	327	2	o	o	NN
cord-353633-a4pu6rlu	327	3	o	o	NN
cord-353633-a4pu6rlu	327	4	f	f	NN
cord-353633-a4pu6rlu	327	5	44	44	CD
cord-353633-a4pu6rlu	327	6	variables	variable	NNS
cord-353633-a4pu6rlu	327	7	(	(	-LRB-
cord-353633-a4pu6rlu	327	8	from	from	IN
cord-353633-a4pu6rlu	327	9	10	10	CD
cord-353633-a4pu6rlu	327	10	up	up	IN
cord-353633-a4pu6rlu	327	11	to	to	TO
cord-353633-a4pu6rlu	327	12	29	29	CD
cord-353633-a4pu6rlu	327	13	)	)	-RRB-
cord-353633-a4pu6rlu	327	14	and	and	CC
cord-353633-a4pu6rlu	327	15	demonstrated	demonstrate	VBD
cord-353633-a4pu6rlu	327	16	high	high	JJ
cord-353633-a4pu6rlu	327	17	sensitivities	sensitivity	NNS
cord-353633-a4pu6rlu	327	18	and	and	CC
cord-353633-a4pu6rlu	327	19	specificities	specificity	NNS
cord-353633-a4pu6rlu	327	20	[	[	-LRB-
cord-353633-a4pu6rlu	327	21	144	144	CD
cord-353633-a4pu6rlu	327	22	]	]	-RRB-
cord-353633-a4pu6rlu	327	23	.	.	.
cord-353633-a4pu6rlu	328	1	The	the	DT
cord-353633-a4pu6rlu	328	2	variables	variable	NNS
cord-353633-a4pu6rlu	328	3	included	include	VBN
cord-353633-a4pu6rlu	328	4	in	in	IN
cord-353633-a4pu6rlu	328	5	the	the	DT
cord-353633-a4pu6rlu	328	6	models	model	NNS
cord-353633-a4pu6rlu	328	7	were	be	VBD
cord-353633-a4pu6rlu	328	8	mainly	mainly	RB
cord-353633-a4pu6rlu	328	9	lipids	lipid	NNS
cord-353633-a4pu6rlu	328	10	and	and	CC
cord-353633-a4pu6rlu	328	11	often	often	RB
cord-353633-a4pu6rlu	328	12	adiponectin	adiponectin	NN
cord-353633-a4pu6rlu	328	13	,	,	,
cord-353633-a4pu6rlu	328	14	which	which	WDT
cord-353633-a4pu6rlu	328	15	its	-PRON-	PRP$
cord-353633-a4pu6rlu	328	16	protective	protective	JJ
cord-353633-a4pu6rlu	328	17	role	role	NN
cord-353633-a4pu6rlu	328	18	against	against	IN
cord-353633-a4pu6rlu	328	19	steatosis	steatosis	NN
cord-353633-a4pu6rlu	328	20	,	,	,
cord-353633-a4pu6rlu	328	21	inflammation	inflammation	NN
cord-353633-a4pu6rlu	328	22	and	and	CC
cord-353633-a4pu6rlu	328	23	liver	liver	NN
cord-353633-a4pu6rlu	328	24	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	328	25	is	be	VBZ
cord-353633-a4pu6rlu	328	26	well	well	RB
cord-353633-a4pu6rlu	328	27	established	establish	VBN
cord-353633-a4pu6rlu	328	28	[	[	-LRB-
cord-353633-a4pu6rlu	328	29	152	152	CD
cord-353633-a4pu6rlu	328	30	,	,	,
cord-353633-a4pu6rlu	328	31	153	153	CD
cord-353633-a4pu6rlu	328	32	,	,	,
cord-353633-a4pu6rlu	328	33	182	182	CD
cord-353633-a4pu6rlu	328	34	]	]	-RRB-
cord-353633-a4pu6rlu	328	35	.	.	.
cord-353633-a4pu6rlu	329	1	A	a	DT
cord-353633-a4pu6rlu	329	2	validation	validation	NN
cord-353633-a4pu6rlu	329	3	cohort	cohort	NN
cord-353633-a4pu6rlu	329	4	did	do	VBD
cord-353633-a4pu6rlu	329	5	not	not	RB
cord-353633-a4pu6rlu	329	6	exist	exist	VB
cord-353633-a4pu6rlu	329	7	,	,	,
cord-353633-a4pu6rlu	329	8	but	but	CC
cord-353633-a4pu6rlu	329	9	2/3	2/3	CD
cord-353633-a4pu6rlu	329	10	of	of	IN
cord-353633-a4pu6rlu	329	11	the	the	DT
cord-353633-a4pu6rlu	329	12	study	study	NN
cord-353633-a4pu6rlu	329	13	population	population	NN
cord-353633-a4pu6rlu	329	14	was	be	VBD
cord-353633-a4pu6rlu	329	15	used	use	VBN
cord-353633-a4pu6rlu	329	16	to	to	TO
cord-353633-a4pu6rlu	329	17	develop	develop	VB
cord-353633-a4pu6rlu	329	18	the	the	DT
cord-353633-a4pu6rlu	329	19	models	model	NNS
cord-353633-a4pu6rlu	329	20	and	and	CC
cord-353633-a4pu6rlu	329	21	1/3	1/3	CD
cord-353633-a4pu6rlu	329	22	to	to	TO
cord-353633-a4pu6rlu	329	23	validate	validate	VB
cord-353633-a4pu6rlu	329	24	it	-PRON-	PRP
cord-353633-a4pu6rlu	329	25	,	,	,
cord-353633-a4pu6rlu	329	26	with	with	IN
cord-353633-a4pu6rlu	329	27	this	this	DT
cord-353633-a4pu6rlu	329	28	procedure	procedure	NN
cord-353633-a4pu6rlu	329	29	being	be	VBG
cord-353633-a4pu6rlu	329	30	repeated	repeat	VBN
cord-353633-a4pu6rlu	329	31	100	100	CD
cord-353633-a4pu6rlu	329	32	times	time	NNS
cord-353633-a4pu6rlu	329	33	with	with	IN
cord-353633-a4pu6rlu	329	34	several	several	JJ
cord-353633-a4pu6rlu	329	35	slices	slice	NNS
cord-353633-a4pu6rlu	329	36	of	of	IN
cord-353633-a4pu6rlu	329	37	data	datum	NNS
cord-353633-a4pu6rlu	329	38	.	.	.
cord-353633-a4pu6rlu	330	1	This	this	DT
cord-353633-a4pu6rlu	330	2	approach	approach	NN
cord-353633-a4pu6rlu	330	3	helps	help	VBZ
cord-353633-a4pu6rlu	330	4	to	to	TO
cord-353633-a4pu6rlu	330	5	control	control	VB
cord-353633-a4pu6rlu	330	6	against	against	IN
cord-353633-a4pu6rlu	330	7	random	random	JJ
cord-353633-a4pu6rlu	330	8	results	result	NNS
cord-353633-a4pu6rlu	331	1	but	but	CC
cord-353633-a4pu6rlu	331	2	it	-PRON-	PRP
cord-353633-a4pu6rlu	331	3	still	still	RB
cord-353633-a4pu6rlu	331	4	does	do	VBZ
cord-353633-a4pu6rlu	331	5	not	not	RB
cord-353633-a4pu6rlu	331	6	address	address	VB
cord-353633-a4pu6rlu	331	7	population	population	NN
cord-353633-a4pu6rlu	331	8	heterogeneity	heterogeneity	NN
cord-353633-a4pu6rlu	331	9	.	.	.
cord-353633-a4pu6rlu	332	1	Nevertheless	nevertheless	RB
cord-353633-a4pu6rlu	332	2	,	,	,
cord-353633-a4pu6rlu	332	3	the	the	DT
cord-353633-a4pu6rlu	332	4	ability	ability	NN
cord-353633-a4pu6rlu	332	5	to	to	TO
cord-353633-a4pu6rlu	332	6	diagnose	diagnose	VB
cord-353633-a4pu6rlu	332	7	between	between	IN
cord-353633-a4pu6rlu	332	8	three	three	CD
cord-353633-a4pu6rlu	332	9	and	and	CC
cord-353633-a4pu6rlu	332	10	not	not	RB
cord-353633-a4pu6rlu	332	11	two	two	CD
cord-353633-a4pu6rlu	332	12	conditions	condition	NNS
cord-353633-a4pu6rlu	332	13	(	(	-LRB-
cord-353633-a4pu6rlu	332	14	healthy	healthy	JJ
cord-353633-a4pu6rlu	332	15	,	,	,
cord-353633-a4pu6rlu	332	16	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	332	17	,	,	,
cord-353633-a4pu6rlu	332	18	NASH	NASH	NNP
cord-353633-a4pu6rlu	332	19	)	)	-RRB-
cord-353633-a4pu6rlu	332	20	can	can	MD
cord-353633-a4pu6rlu	332	21	be	be	VB
cord-353633-a4pu6rlu	332	22	attractive	attractive	JJ
cord-353633-a4pu6rlu	332	23	for	for	IN
cord-353633-a4pu6rlu	332	24	large	large	JJ
cord-353633-a4pu6rlu	332	25	screenings	screening	NNS
cord-353633-a4pu6rlu	332	26	of	of	IN
cord-353633-a4pu6rlu	332	27	high	high	JJ
cord-353633-a4pu6rlu	332	28	-	-	HYPH
cord-353633-a4pu6rlu	332	29	risk	risk	NN
cord-353633-a4pu6rlu	332	30	population	population	NN
cord-353633-a4pu6rlu	332	31	in	in	IN
cord-353633-a4pu6rlu	332	32	primary	primary	JJ
cord-353633-a4pu6rlu	332	33	care	care	NN
cord-353633-a4pu6rlu	332	34	setting	setting	NN
cord-353633-a4pu6rlu	332	35	and	and	CC
cord-353633-a4pu6rlu	332	36	without	without	IN
cord-353633-a4pu6rlu	332	37	the	the	DT
cord-353633-a4pu6rlu	332	38	need	need	NN
cord-353633-a4pu6rlu	332	39	for	for	IN
cord-353633-a4pu6rlu	332	40	any	any	DT
cord-353633-a4pu6rlu	332	41	additional	additional	JJ
cord-353633-a4pu6rlu	332	42	imaging	imaging	NN
cord-353633-a4pu6rlu	332	43	[	[	-LRB-
cord-353633-a4pu6rlu	332	44	144	144	CD
cord-353633-a4pu6rlu	332	45	]	]	-RRB-
cord-353633-a4pu6rlu	332	46	and	and	CC
cord-353633-a4pu6rlu	332	47	should	should	MD
cord-353633-a4pu6rlu	332	48	be	be	VB
cord-353633-a4pu6rlu	332	49	further	further	RB
cord-353633-a4pu6rlu	332	50	evaluated	evaluate	VBN
cord-353633-a4pu6rlu	332	51	in	in	IN
cord-353633-a4pu6rlu	332	52	future	future	JJ
cord-353633-a4pu6rlu	332	53	studies	study	NNS
cord-353633-a4pu6rlu	332	54	.	.	.
cord-353633-a4pu6rlu	333	1	Several	several	JJ
cord-353633-a4pu6rlu	333	2	studies	study	NNS
cord-353633-a4pu6rlu	333	3	have	have	VBP
cord-353633-a4pu6rlu	333	4	attempted	attempt	VBN
cord-353633-a4pu6rlu	333	5	to	to	TO
cord-353633-a4pu6rlu	333	6	develop	develop	VB
cord-353633-a4pu6rlu	333	7	non	non	JJ
cord-353633-a4pu6rlu	333	8	-	-	JJ
cord-353633-a4pu6rlu	333	9	invasive	invasive	JJ
cord-353633-a4pu6rlu	333	10	algorithms	algorithm	NNS
cord-353633-a4pu6rlu	333	11	for	for	IN
cord-353633-a4pu6rlu	333	12	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	333	13	between	between	IN
cord-353633-a4pu6rlu	333	14	advanced	advanced	JJ
cord-353633-a4pu6rlu	333	15	(	(	-LRB-
cord-353633-a4pu6rlu	333	16	stage	stage	NN
cord-353633-a4pu6rlu	333	17	3	3	CD
cord-353633-a4pu6rlu	333	18	-	-	SYM
cord-353633-a4pu6rlu	333	19	4	4	CD
cord-353633-a4pu6rlu	333	20	)	)	-RRB-
cord-353633-a4pu6rlu	333	21	vs	vs	IN
cord-353633-a4pu6rlu	333	22	not	not	RB
cord-353633-a4pu6rlu	333	23	advanced	advanced	JJ
cord-353633-a4pu6rlu	333	24	liver	liver	NN
cord-353633-a4pu6rlu	333	25	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	333	26	(	(	-LRB-
cord-353633-a4pu6rlu	333	27	stage	stage	NN
cord-353633-a4pu6rlu	333	28	0	0	CD
cord-353633-a4pu6rlu	333	29	-	-	SYM
cord-353633-a4pu6rlu	333	30	2	2	CD
cord-353633-a4pu6rlu	333	31	)	)	-RRB-
cord-353633-a4pu6rlu	333	32	.	.	.
cord-353633-a4pu6rlu	334	1	In	in	IN
cord-353633-a4pu6rlu	334	2	one	one	CD
cord-353633-a4pu6rlu	334	3	of	of	IN
cord-353633-a4pu6rlu	334	4	the	the	DT
cord-353633-a4pu6rlu	334	5	most	most	RBS
cord-353633-a4pu6rlu	334	6	comprehensive	comprehensive	JJ
cord-353633-a4pu6rlu	334	7	studies	study	NNS
cord-353633-a4pu6rlu	334	8	so	so	RB
cord-353633-a4pu6rlu	334	9	far	far	RB
cord-353633-a4pu6rlu	334	10	,	,	,
cord-353633-a4pu6rlu	334	11	a	a	DT
cord-353633-a4pu6rlu	334	12	cohort	cohort	NN
cord-353633-a4pu6rlu	334	13	of	of	IN
cord-353633-a4pu6rlu	334	14	156	156	CD
cord-353633-a4pu6rlu	334	15	subjects	subject	NNS
cord-353633-a4pu6rlu	334	16	was	be	VBD
cord-353633-a4pu6rlu	334	17	initially	initially	RB
cord-353633-a4pu6rlu	334	18	used	use	VBN
cord-353633-a4pu6rlu	334	19	to	to	TO
cord-353633-a4pu6rlu	334	20	develop	develop	VB
cord-353633-a4pu6rlu	334	21	an	an	DT
cord-353633-a4pu6rlu	334	22	algorithm	algorithm	NN
cord-353633-a4pu6rlu	334	23	after	after	IN
cord-353633-a4pu6rlu	334	24	a	a	DT
cord-353633-a4pu6rlu	334	25	metabolomic	metabolomic	JJ
cord-353633-a4pu6rlu	334	26	and	and	CC
cord-353633-a4pu6rlu	334	27	lipidomic	lipidomic	NNP
cord-353633-a4pu6rlu	334	28	analysis	analysis	NN
cord-353633-a4pu6rlu	334	29	,	,	,
cord-353633-a4pu6rlu	334	30	which	which	WDT
cord-353633-a4pu6rlu	334	31	finally	finally	RB
cord-353633-a4pu6rlu	334	32	consisted	consist	VBD
cord-353633-a4pu6rlu	334	33	of	of	IN
cord-353633-a4pu6rlu	334	34	10	10	CD
cord-353633-a4pu6rlu	334	35	metabolites	metabolite	NNS
cord-353633-a4pu6rlu	334	36	/	/	SYM
cord-353633-a4pu6rlu	334	37	lipids	lipid	NNS
cord-353633-a4pu6rlu	334	38	.	.	.
cord-353633-a4pu6rlu	335	1	Among	among	IN
cord-353633-a4pu6rlu	335	2	the	the	DT
cord-353633-a4pu6rlu	335	3	10	10	CD
cord-353633-a4pu6rlu	335	4	parameters	parameter	NNS
cord-353633-a4pu6rlu	335	5	,	,	,
cord-353633-a4pu6rlu	335	6	six	six	CD
cord-353633-a4pu6rlu	335	7	were	be	VBD
cord-353633-a4pu6rlu	335	8	cholesterol	cholesterol	NN
cord-353633-a4pu6rlu	335	9	-	-	HYPH
cord-353633-a4pu6rlu	335	10	derived	derive	VBN
cord-353633-a4pu6rlu	335	11	precursors	precursor	NNS
cord-353633-a4pu6rlu	335	12	of	of	IN
cord-353633-a4pu6rlu	335	13	steroid	steroid	NN
cord-353633-a4pu6rlu	335	14	hormones	hormone	NNS
cord-353633-a4pu6rlu	335	15	which	which	WDT
cord-353633-a4pu6rlu	335	16	were	be	VBD
cord-353633-a4pu6rlu	335	17	significantly	significantly	RB
cord-353633-a4pu6rlu	335	18	reduced	reduce	VBN
cord-353633-a4pu6rlu	335	19	in	in	IN
cord-353633-a4pu6rlu	335	20	advanced	advanced	JJ
cord-353633-a4pu6rlu	335	21	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	335	22	,	,	,
cord-353633-a4pu6rlu	335	23	one	one	CD
cord-353633-a4pu6rlu	335	24	was	be	VBD
cord-353633-a4pu6rlu	335	25	the	the	DT
cord-353633-a4pu6rlu	335	26	primary	primary	JJ
cord-353633-a4pu6rlu	335	27	conjugated	conjugated	JJ
cord-353633-a4pu6rlu	335	28	bile	bile	NN
cord-353633-a4pu6rlu	335	29	acid	acid	NN
cord-353633-a4pu6rlu	335	30	,	,	,
cord-353633-a4pu6rlu	335	31	glycopholate	glycopholate	NNP
cord-353633-a4pu6rlu	335	32	,	,	,
cord-353633-a4pu6rlu	335	33	that	that	WDT
cord-353633-a4pu6rlu	335	34	was	be	VBD
cord-353633-a4pu6rlu	335	35	increased	increase	VBN
cord-353633-a4pu6rlu	335	36	in	in	IN
cord-353633-a4pu6rlu	335	37	advanced	advanced	JJ
cord-353633-a4pu6rlu	335	38	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	335	39	and	and	CC
cord-353633-a4pu6rlu	335	40	one	one	CD
cord-353633-a4pu6rlu	335	41	the	the	DT
cord-353633-a4pu6rlu	335	42	aminoacid	aminoacid	JJ
cord-353633-a4pu6rlu	335	43	taurine	taurine	NN
cord-353633-a4pu6rlu	335	44	that	that	WDT
cord-353633-a4pu6rlu	335	45	is	be	VBZ
cord-353633-a4pu6rlu	335	46	associated	associate	VBN
cord-353633-a4pu6rlu	335	47	with	with	IN
cord-353633-a4pu6rlu	335	48	bile	bile	NN
cord-353633-a4pu6rlu	335	49	acid	acid	NN
cord-353633-a4pu6rlu	335	50	conjugation	conjugation	NN
cord-353633-a4pu6rlu	335	51	and	and	CC
cord-353633-a4pu6rlu	335	52	its	-PRON-	PRP$
cord-353633-a4pu6rlu	335	53	levels	level	NNS
cord-353633-a4pu6rlu	335	54	were	be	VBD
cord-353633-a4pu6rlu	335	55	decreased	decrease	VBN
cord-353633-a4pu6rlu	335	56	in	in	IN
cord-353633-a4pu6rlu	335	57	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	335	58	.	.	.
cord-353633-a4pu6rlu	336	1	Finally	finally	RB
cord-353633-a4pu6rlu	336	2	,	,	,
cord-353633-a4pu6rlu	336	3	the	the	DT
cord-353633-a4pu6rlu	336	4	other	other	JJ
cord-353633-a4pu6rlu	336	5	two	two	CD
cord-353633-a4pu6rlu	336	6	parameters	parameter	NNS
cord-353633-a4pu6rlu	336	7	were	be	VBD
cord-353633-a4pu6rlu	336	8	palmitoleate	palmitoleate	NN
cord-353633-a4pu6rlu	336	9	acid	acid	NN
cord-353633-a4pu6rlu	336	10	and	and	CC
cord-353633-a4pu6rlu	336	11	fucose	fucose	NNP
cord-353633-a4pu6rlu	336	12	,	,	,
cord-353633-a4pu6rlu	336	13	which	which	WDT
cord-353633-a4pu6rlu	336	14	were	be	VBD
cord-353633-a4pu6rlu	336	15	both	both	DT
cord-353633-a4pu6rlu	336	16	higher	high	JJR
cord-353633-a4pu6rlu	336	17	in	in	IN
cord-353633-a4pu6rlu	336	18	advanced	advanced	JJ
cord-353633-a4pu6rlu	336	19	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	336	20	.	.	.
cord-353633-a4pu6rlu	337	1	Increased	increase	VBN
cord-353633-a4pu6rlu	337	2	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	337	3	,	,	,
cord-353633-a4pu6rlu	337	4	as	as	IN
cord-353633-a4pu6rlu	337	5	described	describe	VBN
cord-353633-a4pu6rlu	337	6	below	below	IN
cord-353633-a4pu6rlu	337	7	(	(	-LRB-
cord-353633-a4pu6rlu	337	8	s.	s.	NNP
cord-353633-a4pu6rlu	337	9	glycomics	glycomics	NNP
cord-353633-a4pu6rlu	337	10	)	)	-RRB-
cord-353633-a4pu6rlu	337	11	is	be	VBZ
cord-353633-a4pu6rlu	337	12	one	one	CD
cord-353633-a4pu6rlu	337	13	of	of	IN
cord-353633-a4pu6rlu	337	14	the	the	DT
cord-353633-a4pu6rlu	337	15	main	main	JJ
cord-353633-a4pu6rlu	337	16	findings	finding	NNS
cord-353633-a4pu6rlu	337	17	of	of	IN
cord-353633-a4pu6rlu	337	18	studies	study	NNS
cord-353633-a4pu6rlu	337	19	that	that	WDT
cord-353633-a4pu6rlu	337	20	investigated	investigate	VBD
cord-353633-a4pu6rlu	337	21	alterations	alteration	NNS
cord-353633-a4pu6rlu	337	22	in	in	IN
cord-353633-a4pu6rlu	337	23	circulating	circulate	VBG
cord-353633-a4pu6rlu	337	24	glycome	glycome	NN
cord-353633-a4pu6rlu	337	25	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	337	26	and	and	CC
cord-353633-a4pu6rlu	337	27	79	79	CD
cord-353633-a4pu6rlu	337	28	%	%	NN
cord-353633-a4pu6rlu	337	29	specificity	specificity	NN
cord-353633-a4pu6rlu	337	30	for	for	IN
cord-353633-a4pu6rlu	337	31	detecting	detect	VBG
cord-353633-a4pu6rlu	337	32	advanced	advanced	JJ
cord-353633-a4pu6rlu	337	33	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	337	34	,	,	,
cord-353633-a4pu6rlu	337	35	which	which	WDT
cord-353633-a4pu6rlu	337	36	was	be	VBD
cord-353633-a4pu6rlu	337	37	higher	high	JJR
cord-353633-a4pu6rlu	337	38	compared	compare	VBN
cord-353633-a4pu6rlu	337	39	to	to	IN
cord-353633-a4pu6rlu	337	40	FIB-4	FIB-4	NNP
cord-353633-a4pu6rlu	337	41	index	index	NN
cord-353633-a4pu6rlu	337	42	(	(	-LRB-
cord-353633-a4pu6rlu	337	43	39	39	CD
cord-353633-a4pu6rlu	337	44	%	%	NN
cord-353633-a4pu6rlu	337	45	specificity	specificity	NN
cord-353633-a4pu6rlu	337	46	)	)	-RRB-
cord-353633-a4pu6rlu	337	47	and	and	CC
cord-353633-a4pu6rlu	337	48	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	337	49	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	337	50	score	score	NN
cord-353633-a4pu6rlu	337	51	(	(	-LRB-
cord-353633-a4pu6rlu	337	52	59	59	CD
cord-353633-a4pu6rlu	337	53	%	%	NN
cord-353633-a4pu6rlu	337	54	specificity	specificity	NN
cord-353633-a4pu6rlu	337	55	)	)	-RRB-
cord-353633-a4pu6rlu	337	56	[	[	-LRB-
cord-353633-a4pu6rlu	337	57	183	183	CD
cord-353633-a4pu6rlu	337	58	]	]	-RRB-
cord-353633-a4pu6rlu	337	59	.	.	.
cord-353633-a4pu6rlu	338	1	Finally	finally	RB
cord-353633-a4pu6rlu	338	2	,	,	,
cord-353633-a4pu6rlu	338	3	very	very	RB
cord-353633-a4pu6rlu	338	4	few	few	JJ
cord-353633-a4pu6rlu	338	5	studies	study	NNS
cord-353633-a4pu6rlu	338	6	have	have	VBP
cord-353633-a4pu6rlu	338	7	tried	try	VBN
cord-353633-a4pu6rlu	338	8	to	to	TO
cord-353633-a4pu6rlu	338	9	develop	develop	VB
cord-353633-a4pu6rlu	338	10	such	such	JJ
cord-353633-a4pu6rlu	338	11	models	model	NNS
cord-353633-a4pu6rlu	338	12	in	in	IN
cord-353633-a4pu6rlu	338	13	pediatric	pediatric	JJ
cord-353633-a4pu6rlu	338	14	population	population	NN
cord-353633-a4pu6rlu	338	15	.	.	.
cord-353633-a4pu6rlu	339	1	The	the	DT
cord-353633-a4pu6rlu	339	2	most	most	RBS
cord-353633-a4pu6rlu	339	3	comprehensive	comprehensive	JJ
cord-353633-a4pu6rlu	339	4	one	one	NN
cord-353633-a4pu6rlu	339	5	so	so	RB
cord-353633-a4pu6rlu	339	6	far	far	RB
cord-353633-a4pu6rlu	339	7	included	include	VBD
cord-353633-a4pu6rlu	339	8	222	222	CD
cord-353633-a4pu6rlu	339	9	children	child	NNS
cord-353633-a4pu6rlu	339	10	and	and	CC
cord-353633-a4pu6rlu	339	11	adolescent	adolescent	JJ
cord-353633-a4pu6rlu	339	12	with	with	IN
cord-353633-a4pu6rlu	339	13	biopsy	biopsy	NN
cord-353633-a4pu6rlu	339	14	-	-	HYPH
cord-353633-a4pu6rlu	339	15	or	or	CC
cord-353633-a4pu6rlu	339	16	MRI	MRI	NNP
cord-353633-a4pu6rlu	339	17	-	-	HYPH
cord-353633-a4pu6rlu	339	18	proven	prove	VBN
cord-353633-a4pu6rlu	339	19	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	339	20	and	and	CC
cord-353633-a4pu6rlu	339	21	337	337	CD
cord-353633-a4pu6rlu	339	22	without	without	IN
cord-353633-a4pu6rlu	339	23	the	the	DT
cord-353633-a4pu6rlu	339	24	disease	disease	NN
cord-353633-a4pu6rlu	339	25	.	.	.
cord-353633-a4pu6rlu	340	1	Metabolomics	metabolomic	NNS
cord-353633-a4pu6rlu	340	2	identified	identify	VBD
cord-353633-a4pu6rlu	340	3	11	11	CD
cord-353633-a4pu6rlu	340	4	metabolites	metabolite	NNS
cord-353633-a4pu6rlu	340	5	of	of	IN
cord-353633-a4pu6rlu	340	6	interest	interest	NN
cord-353633-a4pu6rlu	340	7	which	which	WDT
cord-353633-a4pu6rlu	340	8	together	together	RB
cord-353633-a4pu6rlu	340	9	with	with	IN
cord-353633-a4pu6rlu	340	10	waist	waist	NN
cord-353633-a4pu6rlu	340	11	circumference	circumference	NN
cord-353633-a4pu6rlu	340	12	,	,	,
cord-353633-a4pu6rlu	340	13	whole	whole	JJ
cord-353633-a4pu6rlu	340	14	-	-	HYPH
cord-353633-a4pu6rlu	340	15	body	body	NN
cord-353633-a4pu6rlu	340	16	insulin	insulin	NN
cord-353633-a4pu6rlu	340	17	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	340	18	index	index	NN
cord-353633-a4pu6rlu	340	19	and	and	CC
cord-353633-a4pu6rlu	340	20	triglycerides	triglyceride	NNS
cord-353633-a4pu6rlu	340	21	could	could	MD
cord-353633-a4pu6rlu	340	22	detect	detect	VB
cord-353633-a4pu6rlu	340	23	the	the	DT
cord-353633-a4pu6rlu	340	24	presence	presence	NN
cord-353633-a4pu6rlu	340	25	of	of	IN
cord-353633-a4pu6rlu	340	26	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	340	27	with	with	IN
cord-353633-a4pu6rlu	340	28	97	97	CD
cord-353633-a4pu6rlu	340	29	%	%	NN
cord-353633-a4pu6rlu	340	30	specificity	specificity	NN
cord-353633-a4pu6rlu	340	31	and	and	CC
cord-353633-a4pu6rlu	340	32	73	73	CD
cord-353633-a4pu6rlu	340	33	%	%	NN
cord-353633-a4pu6rlu	340	34	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	340	35	[	[	-LRB-
cord-353633-a4pu6rlu	340	36	184	184	CD
cord-353633-a4pu6rlu	340	37	]	]	-RRB-
cord-353633-a4pu6rlu	340	38	.	.	.
cord-353633-a4pu6rlu	341	1	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	341	2	is	be	VBZ
cord-353633-a4pu6rlu	341	3	considered	consider	VBN
cord-353633-a4pu6rlu	341	4	an	an	DT
cord-353633-a4pu6rlu	341	5	unmet	unmet	JJ
cord-353633-a4pu6rlu	341	6	clinical	clinical	JJ
cord-353633-a4pu6rlu	341	7	need	need	NN
cord-353633-a4pu6rlu	341	8	.	.	.
cord-353633-a4pu6rlu	342	1	Several	several	JJ
cord-353633-a4pu6rlu	342	2	treatments	treatment	NNS
cord-353633-a4pu6rlu	342	3	that	that	WDT
cord-353633-a4pu6rlu	342	4	are	be	VBP
cord-353633-a4pu6rlu	342	5	currently	currently	RB
cord-353633-a4pu6rlu	342	6	in	in	IN
cord-353633-a4pu6rlu	342	7	the	the	DT
cord-353633-a4pu6rlu	342	8	pipeline	pipeline	NN
cord-353633-a4pu6rlu	342	9	restore	restore	VBP
cord-353633-a4pu6rlu	342	10	many	many	JJ
cord-353633-a4pu6rlu	342	11	of	of	IN
cord-353633-a4pu6rlu	342	12	the	the	DT
cord-353633-a4pu6rlu	342	13	abnormalities	abnormality	NNS
cord-353633-a4pu6rlu	342	14	observed	observe	VBN
cord-353633-a4pu6rlu	342	15	in	in	IN
cord-353633-a4pu6rlu	342	16	the	the	DT
cord-353633-a4pu6rlu	342	17	lipidome	lipidome	NN
cord-353633-a4pu6rlu	342	18	.	.	.
cord-353633-a4pu6rlu	343	1	Specifically	specifically	RB
cord-353633-a4pu6rlu	343	2	,	,	,
cord-353633-a4pu6rlu	343	3	agonists	agonist	NNS
cord-353633-a4pu6rlu	343	4	of	of	IN
cord-353633-a4pu6rlu	343	5	farnesoid	farnesoid	NNP
cord-353633-a4pu6rlu	343	6	X	x	NN
cord-353633-a4pu6rlu	343	7	receptor	receptor	NN
cord-353633-a4pu6rlu	343	8	(	(	-LRB-
cord-353633-a4pu6rlu	343	9	FXR	FXR	NNP
cord-353633-a4pu6rlu	343	10	)	)	-RRB-
cord-353633-a4pu6rlu	343	11	reduce	reduce	VBP
cord-353633-a4pu6rlu	343	12	lipotoxicity	lipotoxicity	NN
cord-353633-a4pu6rlu	343	13	by	by	IN
cord-353633-a4pu6rlu	343	14	promoting	promote	VBG
cord-353633-a4pu6rlu	343	15	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	343	16	beta	beta	NN
cord-353633-a4pu6rlu	343	17	-	-	HYPH
cord-353633-a4pu6rlu	343	18	oxidation	oxidation	NN
cord-353633-a4pu6rlu	343	19	,	,	,
cord-353633-a4pu6rlu	343	20	decreasing	decrease	VBG
cord-353633-a4pu6rlu	343	21	de	de	FW
cord-353633-a4pu6rlu	343	22	novo	novo	NNP
cord-353633-a4pu6rlu	343	23	lipogenesis	lipogenesi	NNS
cord-353633-a4pu6rlu	343	24	and	and	CC
cord-353633-a4pu6rlu	343	25	stimulating	stimulate	VBG
cord-353633-a4pu6rlu	343	26	cholesterol	cholesterol	NN
cord-353633-a4pu6rlu	343	27	excretion	excretion	NN
cord-353633-a4pu6rlu	343	28	[	[	-LRB-
cord-353633-a4pu6rlu	343	29	142	142	CD
cord-353633-a4pu6rlu	343	30	]	]	-RRB-
cord-353633-a4pu6rlu	343	31	.	.	.
cord-353633-a4pu6rlu	344	1	In	in	IN
cord-353633-a4pu6rlu	344	2	Phase	phase	NN
cord-353633-a4pu6rlu	344	3	2	2	CD
cord-353633-a4pu6rlu	344	4	clinical	clinical	JJ
cord-353633-a4pu6rlu	344	5	trials	trial	NNS
cord-353633-a4pu6rlu	344	6	and	and	CC
cord-353633-a4pu6rlu	344	7	in	in	IN
cord-353633-a4pu6rlu	344	8	an	an	DT
cord-353633-a4pu6rlu	344	9	interim	interim	JJ
cord-353633-a4pu6rlu	344	10	analysis	analysis	NN
cord-353633-a4pu6rlu	344	11	of	of	IN
cord-353633-a4pu6rlu	344	12	an	an	DT
cord-353633-a4pu6rlu	344	13	ongoing	ongoing	JJ
cord-353633-a4pu6rlu	344	14	phase	phase	NN
cord-353633-a4pu6rlu	344	15	3	3	CD
cord-353633-a4pu6rlu	344	16	clinical	clinical	JJ
cord-353633-a4pu6rlu	344	17	trial	trial	NN
cord-353633-a4pu6rlu	344	18	,	,	,
cord-353633-a4pu6rlu	344	19	obeticholic	obeticholic	JJ
cord-353633-a4pu6rlu	344	20	acid	acid	NN
cord-353633-a4pu6rlu	344	21	reduced	reduce	VBN
cord-353633-a4pu6rlu	344	22	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	344	23	steatosis	steatosis	NN
cord-353633-a4pu6rlu	344	24	,	,	,
cord-353633-a4pu6rlu	344	25	inflammation	inflammation	NN
cord-353633-a4pu6rlu	344	26	and	and	CC
cord-353633-a4pu6rlu	344	27	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	344	28	compared	compare	VBN
cord-353633-a4pu6rlu	344	29	to	to	IN
cord-353633-a4pu6rlu	344	30	placebo	placebo	NN
cord-353633-a4pu6rlu	344	31	[	[	-LRB-
cord-353633-a4pu6rlu	344	32	142	142	CD
cord-353633-a4pu6rlu	344	33	,	,	,
cord-353633-a4pu6rlu	344	34	[	[	-LRB-
cord-353633-a4pu6rlu	344	35	185	185	CD
cord-353633-a4pu6rlu	344	36	]	]	-RRB-
cord-353633-a4pu6rlu	344	37	[	[	-LRB-
cord-353633-a4pu6rlu	344	38	186	186	CD
cord-353633-a4pu6rlu	344	39	]	]	-RRB-
cord-353633-a4pu6rlu	344	40	[	[	-LRB-
cord-353633-a4pu6rlu	344	41	187	187	CD
cord-353633-a4pu6rlu	344	42	]	]	-RRB-
cord-353633-a4pu6rlu	344	43	.	.	.
cord-353633-a4pu6rlu	345	1	Dual	dual	JJ
cord-353633-a4pu6rlu	345	2	PPARα	PPARα	NNS
cord-353633-a4pu6rlu	345	3	and	and	CC
cord-353633-a4pu6rlu	345	4	PPARδ	PPARδ	NNS
cord-353633-a4pu6rlu	345	5	agonists	agonist	NNS
cord-353633-a4pu6rlu	345	6	(	(	-LRB-
cord-353633-a4pu6rlu	345	7	e.g.	e.g.	RB
cord-353633-a4pu6rlu	345	8	elafibranor	elafibranor	NNP
cord-353633-a4pu6rlu	345	9	)	)	-RRB-
cord-353633-a4pu6rlu	345	10	also	also	RB
cord-353633-a4pu6rlu	345	11	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	345	12	mitochondrial	mitochondrial	NN
cord-353633-a4pu6rlu	345	13	and	and	CC
cord-353633-a4pu6rlu	345	14	peroxisome	peroxisome	NN
cord-353633-a4pu6rlu	345	15	β	β	NN
cord-353633-a4pu6rlu	345	16	-	-	HYPH
cord-353633-a4pu6rlu	345	17	oxidation	oxidation	NN
cord-353633-a4pu6rlu	345	18	as	as	RB
cord-353633-a4pu6rlu	345	19	well	well	RB
cord-353633-a4pu6rlu	345	20	as	as	IN
cord-353633-a4pu6rlu	345	21	omega	omega	NN
cord-353633-a4pu6rlu	345	22	-	-	HYPH
cord-353633-a4pu6rlu	345	23	oxidation	oxidation	NN
cord-353633-a4pu6rlu	346	1	[	[	-LRB-
cord-353633-a4pu6rlu	346	2	188-	188-	CD
cord-353633-a4pu6rlu	346	3	J	J	NNP
cord-353633-a4pu6rlu	346	4	o	o	NN
cord-353633-a4pu6rlu	346	5	u	u	NN
cord-353633-a4pu6rlu	346	6	r	r	NN
cord-353633-a4pu6rlu	346	7	n	n	NN
cord-353633-a4pu6rlu	346	8	a	a	DT
cord-353633-a4pu6rlu	346	9	l	l	NN
cord-353633-a4pu6rlu	346	10	P	p	NN
cord-353633-a4pu6rlu	346	11	r	r	NN
cord-353633-a4pu6rlu	346	12	e	e	NN
cord-353633-a4pu6rlu	347	1	-p	-p	:
cord-353633-a4pu6rlu	348	1	r	r	NN
cord-353633-a4pu6rlu	348	2	o	o	NN
cord-353633-a4pu6rlu	348	3	o	o	NN
cord-353633-a4pu6rlu	348	4	f	f	NN
cord-353633-a4pu6rlu	348	5	46	46	CD
cord-353633-a4pu6rlu	348	6	191	191	CD
cord-353633-a4pu6rlu	348	7	]	]	-RRB-
cord-353633-a4pu6rlu	348	8	.	.	.
cord-353633-a4pu6rlu	349	1	PPARγ	PPARγ	NNS
cord-353633-a4pu6rlu	349	2	agonists	agonist	NNS
cord-353633-a4pu6rlu	349	3	reduce	reduce	VBP
cord-353633-a4pu6rlu	349	4	circulating	circulate	VBG
cord-353633-a4pu6rlu	349	5	FFA	FFA	NNP
cord-353633-a4pu6rlu	349	6	and	and	CC
cord-353633-a4pu6rlu	349	7	consequently	consequently	RB
cord-353633-a4pu6rlu	349	8	the	the	DT
cord-353633-a4pu6rlu	349	9	flow	flow	NN
cord-353633-a4pu6rlu	349	10	of	of	IN
cord-353633-a4pu6rlu	349	11	SFA	SFA	NNP
cord-353633-a4pu6rlu	349	12	to	to	IN
cord-353633-a4pu6rlu	349	13	the	the	DT
cord-353633-a4pu6rlu	349	14	liver	liver	NN
cord-353633-a4pu6rlu	349	15	,	,	,
cord-353633-a4pu6rlu	349	16	they	-PRON-	PRP
cord-353633-a4pu6rlu	349	17	improve	improve	VBP
cord-353633-a4pu6rlu	349	18	insulin	insulin	NN
cord-353633-a4pu6rlu	349	19	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	349	20	and	and	CC
cord-353633-a4pu6rlu	349	21	guide	guide	NN
cord-353633-a4pu6rlu	349	22	macrophage	macrophage	NN
cord-353633-a4pu6rlu	349	23	and	and	CC
cord-353633-a4pu6rlu	349	24	Kupffer	Kupffer	NNP
cord-353633-a4pu6rlu	349	25	cell	cell	NN
cord-353633-a4pu6rlu	349	26	polarization	polarization	NN
cord-353633-a4pu6rlu	349	27	from	from	IN
cord-353633-a4pu6rlu	349	28	the	the	DT
cord-353633-a4pu6rlu	349	29	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	349	30	M1	M1	NNP
cord-353633-a4pu6rlu	349	31	phenotype	phenotype	NN
cord-353633-a4pu6rlu	349	32	towards	towards	IN
cord-353633-a4pu6rlu	349	33	to	to	IN
cord-353633-a4pu6rlu	349	34	the	the	DT
cord-353633-a4pu6rlu	349	35	anti	anti	JJ
cord-353633-a4pu6rlu	349	36	-	-	JJ
cord-353633-a4pu6rlu	349	37	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	349	38	M2	M2	NNP
cord-353633-a4pu6rlu	349	39	one	one	CD
cord-353633-a4pu6rlu	349	40	[	[	-LRB-
cord-353633-a4pu6rlu	349	41	142	142	CD
cord-353633-a4pu6rlu	349	42	,	,	,
cord-353633-a4pu6rlu	349	43	167	167	CD
cord-353633-a4pu6rlu	349	44	]	]	-RRB-
cord-353633-a4pu6rlu	349	45	.	.	.
cord-353633-a4pu6rlu	350	1	Various	various	JJ
cord-353633-a4pu6rlu	350	2	selective	selective	JJ
cord-353633-a4pu6rlu	350	3	PPARγ	PPARγ	NNS
cord-353633-a4pu6rlu	350	4	modulators	modulator	NNS
cord-353633-a4pu6rlu	350	5	,	,	,
cord-353633-a4pu6rlu	350	6	dual	dual	JJ
cord-353633-a4pu6rlu	350	7	PPARα	PPARα	NNS
cord-353633-a4pu6rlu	350	8	/	/	SYM
cord-353633-a4pu6rlu	350	9	γ	γ	NN
cord-353633-a4pu6rlu	350	10	agonists	agonist	NNS
cord-353633-a4pu6rlu	350	11	(	(	-LRB-
cord-353633-a4pu6rlu	350	12	e.g.	e.g.	RB
cord-353633-a4pu6rlu	350	13	Saroglitazar	Saroglitazar	NNP
cord-353633-a4pu6rlu	350	14	)	)	-RRB-
cord-353633-a4pu6rlu	350	15	or	or	CC
cord-353633-a4pu6rlu	350	16	Pan	Pan	NNP
cord-353633-a4pu6rlu	350	17	-	-	JJ
cord-353633-a4pu6rlu	350	18	PPAR	PPAR	NNP
cord-353633-a4pu6rlu	350	19	agonists	agonist	NNS
cord-353633-a4pu6rlu	350	20	(	(	-LRB-
cord-353633-a4pu6rlu	350	21	e.g.	e.g.	IN
cord-353633-a4pu6rlu	350	22	lanifibranor	lanifibranor	NNP
cord-353633-a4pu6rlu	350	23	)	)	-RRB-
cord-353633-a4pu6rlu	350	24	have	have	VBP
cord-353633-a4pu6rlu	350	25	shown	show	VBN
cord-353633-a4pu6rlu	350	26	promising	promising	JJ
cord-353633-a4pu6rlu	350	27	results	result	NNS
cord-353633-a4pu6rlu	350	28	in	in	IN
cord-353633-a4pu6rlu	350	29	human	human	JJ
cord-353633-a4pu6rlu	350	30	studies	study	NNS
cord-353633-a4pu6rlu	350	31	and	and	CC
cord-353633-a4pu6rlu	350	32	are	be	VBP
cord-353633-a4pu6rlu	350	33	currently	currently	RB
cord-353633-a4pu6rlu	350	34	under	under	IN
cord-353633-a4pu6rlu	350	35	evaluation	evaluation	NN
cord-353633-a4pu6rlu	350	36	in	in	IN
cord-353633-a4pu6rlu	350	37	phase	phase	NN
cord-353633-a4pu6rlu	350	38	2	2	CD
cord-353633-a4pu6rlu	350	39	or	or	CC
cord-353633-a4pu6rlu	350	40	phase	phase	VB
cord-353633-a4pu6rlu	350	41	3	3	CD
cord-353633-a4pu6rlu	350	42	clinical	clinical	JJ
cord-353633-a4pu6rlu	350	43	trials	trial	NNS
cord-353633-a4pu6rlu	350	44	[	[	-LRB-
cord-353633-a4pu6rlu	350	45	142	142	CD
cord-353633-a4pu6rlu	350	46	,	,	,
cord-353633-a4pu6rlu	350	47	[	[	-LRB-
cord-353633-a4pu6rlu	350	48	192	192	CD
cord-353633-a4pu6rlu	350	49	]	]	-RRB-
cord-353633-a4pu6rlu	350	50	[	[	-LRB-
cord-353633-a4pu6rlu	350	51	193	193	CD
cord-353633-a4pu6rlu	350	52	]	]	-RRB-
cord-353633-a4pu6rlu	350	53	[	[	-LRB-
cord-353633-a4pu6rlu	350	54	194	194	CD
cord-353633-a4pu6rlu	350	55	]	]	-RRB-
cord-353633-a4pu6rlu	350	56	.	.	.
cord-353633-a4pu6rlu	351	1	In	in	IN
cord-353633-a4pu6rlu	351	2	this	this	DT
cord-353633-a4pu6rlu	351	3	context	context	NN
cord-353633-a4pu6rlu	351	4	,	,	,
cord-353633-a4pu6rlu	351	5	it	-PRON-	PRP
cord-353633-a4pu6rlu	351	6	was	be	VBD
cord-353633-a4pu6rlu	351	7	recently	recently	RB
cord-353633-a4pu6rlu	351	8	announced	announce	VBN
cord-353633-a4pu6rlu	351	9	,	,	,
cord-353633-a4pu6rlu	351	10	that	that	DT
cord-353633-a4pu6rlu	351	11	lanifibranor	lanifibranor	NNP
cord-353633-a4pu6rlu	351	12	met	meet	VBD
cord-353633-a4pu6rlu	351	13	the	the	DT
cord-353633-a4pu6rlu	351	14	primary	primary	JJ
cord-353633-a4pu6rlu	351	15	endpoint	endpoint	NN
cord-353633-a4pu6rlu	351	16	of	of	IN
cord-353633-a4pu6rlu	351	17	a	a	DT
cord-353633-a4pu6rlu	351	18	reduction	reduction	NN
cord-353633-a4pu6rlu	351	19	in	in	IN
cord-353633-a4pu6rlu	351	20	steatosis	steatosis	NN
cord-353633-a4pu6rlu	351	21	activity	activity	NN
cord-353633-a4pu6rlu	351	22	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	351	23	score	score	NN
cord-353633-a4pu6rlu	351	24	,	,	,
cord-353633-a4pu6rlu	351	25	including	include	VBG
cord-353633-a4pu6rlu	351	26	NASH	NASH	NNP
cord-353633-a4pu6rlu	351	27	resolution	resolution	NN
cord-353633-a4pu6rlu	351	28	without	without	IN
cord-353633-a4pu6rlu	351	29	worsening	worsen	VBG
cord-353633-a4pu6rlu	351	30	of	of	IN
cord-353633-a4pu6rlu	351	31	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	351	32	in	in	IN
cord-353633-a4pu6rlu	351	33	a	a	DT
cord-353633-a4pu6rlu	351	34	Phase	Phase	NNP
cord-353633-a4pu6rlu	351	35	II	II	NNP
cord-353633-a4pu6rlu	351	36	clinical	clinical	JJ
cord-353633-a4pu6rlu	351	37	trial	trial	NN
cord-353633-a4pu6rlu	351	38	,	,	,
cord-353633-a4pu6rlu	351	39	thus	thus	RB
cord-353633-a4pu6rlu	351	40	being	be	VBG
cord-353633-a4pu6rlu	351	41	the	the	DT
cord-353633-a4pu6rlu	351	42	first	first	JJ
cord-353633-a4pu6rlu	351	43	study	study	NN
cord-353633-a4pu6rlu	351	44	that	that	WDT
cord-353633-a4pu6rlu	351	45	met	meet	VBD
cord-353633-a4pu6rlu	351	46	both	both	DT
cord-353633-a4pu6rlu	351	47	FDA	FDA	NNP
cord-353633-a4pu6rlu	351	48	and	and	CC
cord-353633-a4pu6rlu	351	49	EMA	EMA	NNP
cord-353633-a4pu6rlu	351	50	regulatory	regulatory	JJ
cord-353633-a4pu6rlu	351	51	endpoints	endpoint	NNS
cord-353633-a4pu6rlu	351	52	for	for	IN
cord-353633-a4pu6rlu	351	53	accelerated	accelerated	JJ
cord-353633-a4pu6rlu	351	54	approval	approval	NN
cord-353633-a4pu6rlu	351	55	[	[	-LRB-
cord-353633-a4pu6rlu	351	56	195	195	CD
cord-353633-a4pu6rlu	351	57	]	]	-RRB-
cord-353633-a4pu6rlu	351	58	ACC	ACC	NNP
cord-353633-a4pu6rlu	351	59	inhibitors	inhibitor	NNS
cord-353633-a4pu6rlu	351	60	(	(	-LRB-
cord-353633-a4pu6rlu	351	61	e.g.	e.g.	RB
cord-353633-a4pu6rlu	351	62	firsocostat	firsocostat	NN
cord-353633-a4pu6rlu	351	63	)	)	-RRB-
cord-353633-a4pu6rlu	351	64	attenuate	attenuate	VBP
cord-353633-a4pu6rlu	351	65	the	the	DT
cord-353633-a4pu6rlu	351	66	function	function	NN
cord-353633-a4pu6rlu	351	67	of	of	IN
cord-353633-a4pu6rlu	351	68	acetyl	acetyl	NN
cord-353633-a4pu6rlu	351	69	-	-	HYPH
cord-353633-a4pu6rlu	351	70	coA	coA	NNP
cord-353633-a4pu6rlu	351	71	carboxylase	carboxylase	NN
cord-353633-a4pu6rlu	351	72	(	(	-LRB-
cord-353633-a4pu6rlu	351	73	ACC	ACC	NNP
cord-353633-a4pu6rlu	351	74	)	)	-RRB-
cord-353633-a4pu6rlu	351	75	that	that	WDT
cord-353633-a4pu6rlu	351	76	catalyzes	catalyze	VBZ
cord-353633-a4pu6rlu	351	77	the	the	DT
cord-353633-a4pu6rlu	351	78	conversion	conversion	NN
cord-353633-a4pu6rlu	351	79	of	of	IN
cord-353633-a4pu6rlu	351	80	acetyl	acetyl	NN
cord-353633-a4pu6rlu	351	81	-	-	HYPH
cord-353633-a4pu6rlu	351	82	CoA	coa	NN
cord-353633-a4pu6rlu	351	83	to	to	IN
cord-353633-a4pu6rlu	351	84	malonyl	malonyl	NNP
cord-353633-a4pu6rlu	351	85	-	-	HYPH
cord-353633-a4pu6rlu	351	86	CoA.	coa.	NN
cord-353633-a4pu6rlu	352	1	Consequently	consequently	RB
cord-353633-a4pu6rlu	352	2	,	,	,
cord-353633-a4pu6rlu	352	3	malonyl	malonyl	NNP
cord-353633-a4pu6rlu	352	4	-	-	HYPH
cord-353633-a4pu6rlu	352	5	CoA	CoA	NNP
cord-353633-a4pu6rlu	352	6	is	be	VBZ
cord-353633-a4pu6rlu	352	7	reduced	reduce	VBN
cord-353633-a4pu6rlu	352	8	and	and	CC
cord-353633-a4pu6rlu	352	9	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	352	10	de	de	FW
cord-353633-a4pu6rlu	352	11	novo	novo	NNP
cord-353633-a4pu6rlu	352	12	lipogenesis	lipogenesi	NNS
cord-353633-a4pu6rlu	352	13	as	as	RB
cord-353633-a4pu6rlu	352	14	well	well	RB
cord-353633-a4pu6rlu	352	15	as	as	IN
cord-353633-a4pu6rlu	352	16	mitochondrial	mitochondrial	NN
cord-353633-a4pu6rlu	352	17	FA	fa	NN
cord-353633-a4pu6rlu	353	1	beta	beta	JJ
cord-353633-a4pu6rlu	353	2	oxidation	oxidation	NN
cord-353633-a4pu6rlu	353	3	are	be	VBP
cord-353633-a4pu6rlu	353	4	downregulated	downregulate	VBN
cord-353633-a4pu6rlu	353	5	[	[	-LRB-
cord-353633-a4pu6rlu	353	6	142	142	CD
cord-353633-a4pu6rlu	353	7	,	,	,
cord-353633-a4pu6rlu	353	8	196	196	CD
cord-353633-a4pu6rlu	353	9	]	]	-RRB-
cord-353633-a4pu6rlu	353	10	.	.	.
cord-353633-a4pu6rlu	354	1	In	in	IN
cord-353633-a4pu6rlu	354	2	humans	human	NNS
cord-353633-a4pu6rlu	354	3	,	,	,
cord-353633-a4pu6rlu	354	4	ACC	ACC	NNP
cord-353633-a4pu6rlu	354	5	inhibitors	inhibitor	NNS
cord-353633-a4pu6rlu	354	6	reduce	reduce	VBP
cord-353633-a4pu6rlu	354	7	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	354	8	steatosis	steatosis	NN
cord-353633-a4pu6rlu	354	9	and	and	CC
cord-353633-a4pu6rlu	354	10	on	on	RB
cord-353633-a4pu6rlu	354	11	-	-	HYPH
cord-353633-a4pu6rlu	354	12	going	go	VBG
cord-353633-a4pu6rlu	354	13	clinical	clinical	JJ
cord-353633-a4pu6rlu	354	14	trials	trial	NNS
cord-353633-a4pu6rlu	354	15	will	will	MD
cord-353633-a4pu6rlu	354	16	evaluate	evaluate	VB
cord-353633-a4pu6rlu	354	17	their	-PRON-	PRP$
cord-353633-a4pu6rlu	354	18	effect	effect	NN
cord-353633-a4pu6rlu	354	19	also	also	RB
cord-353633-a4pu6rlu	354	20	on	on	IN
cord-353633-a4pu6rlu	354	21	inflammation	inflammation	NN
cord-353633-a4pu6rlu	354	22	and	and	CC
cord-353633-a4pu6rlu	354	23	liver	liver	NN
cord-353633-a4pu6rlu	354	24	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	354	25	[	[	-LRB-
cord-353633-a4pu6rlu	354	26	142	142	CD
cord-353633-a4pu6rlu	354	27	,	,	,
cord-353633-a4pu6rlu	354	28	196	196	CD
cord-353633-a4pu6rlu	354	29	]	]	-RRB-
cord-353633-a4pu6rlu	354	30	.	.	.
cord-353633-a4pu6rlu	355	1	Regarding	regard	VBG
cord-353633-a4pu6rlu	355	2	LPC	LPC	NNP
cord-353633-a4pu6rlu	355	3	accumulation	accumulation	NN
cord-353633-a4pu6rlu	355	4	,	,	,
cord-353633-a4pu6rlu	355	5	animal	animal	NN
cord-353633-a4pu6rlu	355	6	studies	study	NNS
cord-353633-a4pu6rlu	355	7	have	have	VBP
cord-353633-a4pu6rlu	355	8	shown	show	VBN
cord-353633-a4pu6rlu	355	9	that	that	IN
cord-353633-a4pu6rlu	355	10	interruption	interruption	NN
cord-353633-a4pu6rlu	355	11	of	of	IN
cord-353633-a4pu6rlu	355	12	the	the	DT
cord-353633-a4pu6rlu	355	13	generation	generation	NN
cord-353633-a4pu6rlu	355	14	of	of	IN
cord-353633-a4pu6rlu	355	15	LPC	LPC	NNP
cord-353633-a4pu6rlu	355	16	from	from	IN
cord-353633-a4pu6rlu	355	17	PC	pc	NN
cord-353633-a4pu6rlu	355	18	with	with	IN
cord-353633-a4pu6rlu	355	19	inhibition	inhibition	NN
cord-353633-a4pu6rlu	355	20	of	of	IN
cord-353633-a4pu6rlu	355	21	PLA2	PLA2	NNP
cord-353633-a4pu6rlu	355	22	results	result	NNS
cord-353633-a4pu6rlu	355	23	in	in	IN
cord-353633-a4pu6rlu	355	24	normalization	normalization	NN
cord-353633-a4pu6rlu	355	25	of	of	IN
cord-353633-a4pu6rlu	355	26	PC	pc	NN
cord-353633-a4pu6rlu	355	27	levels	level	NNS
cord-353633-a4pu6rlu	355	28	,	,	,
cord-353633-a4pu6rlu	355	29	prevention	prevention	NN
cord-353633-a4pu6rlu	355	30	of	of	IN
cord-353633-a4pu6rlu	355	31	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	355	32	and	and	CC
cord-353633-a4pu6rlu	355	33	reversal	reversal	NN
cord-353633-a4pu6rlu	355	34	of	of	IN
cord-353633-a4pu6rlu	355	35	NASH	NASH	NNP
cord-353633-a4pu6rlu	355	36	and	and	CC
cord-353633-a4pu6rlu	355	37	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	355	38	[	[	-LRB-
cord-353633-a4pu6rlu	355	39	158	158	CD
cord-353633-a4pu6rlu	355	40	,	,	,
cord-353633-a4pu6rlu	355	41	197	197	CD
cord-353633-a4pu6rlu	355	42	]	]	-RRB-
cord-353633-a4pu6rlu	355	43	.	.	.
cord-353633-a4pu6rlu	356	1	Several	several	JJ
cord-353633-a4pu6rlu	356	2	treatments	treatment	NNS
cord-353633-a4pu6rlu	356	3	are	be	VBP
cord-353633-a4pu6rlu	356	4	targeting	target	VBG
cord-353633-a4pu6rlu	356	5	also	also	RB
cord-353633-a4pu6rlu	356	6	ceramide	ceramide	NN
cord-353633-a4pu6rlu	356	7	levels	level	NNS
cord-353633-a4pu6rlu	356	8	by	by	IN
cord-353633-a4pu6rlu	356	9	aiming	aim	VBG
cord-353633-a4pu6rlu	356	10	to	to	TO
cord-353633-a4pu6rlu	356	11	reduce	reduce	VB
cord-353633-a4pu6rlu	356	12	ceramide	ceramide	NN
cord-353633-a4pu6rlu	356	13	synthesis	synthesis	NN
cord-353633-a4pu6rlu	356	14	(	(	-LRB-
cord-353633-a4pu6rlu	356	15	de	de	FW
cord-353633-a4pu6rlu	356	16	novo	novo	NNP
cord-353633-a4pu6rlu	356	17	or	or	CC
cord-353633-a4pu6rlu	356	18	through	through	IN
cord-353633-a4pu6rlu	356	19	hydrolysis	hydrolysis	NN
cord-353633-a4pu6rlu	356	20	from	from	IN
cord-353633-a4pu6rlu	356	21	sphingomyelin	sphingomyelin	NN
cord-353633-a4pu6rlu	356	22	)	)	-RRB-
cord-353633-a4pu6rlu	356	23	or	or	CC
cord-353633-a4pu6rlu	356	24	J	J	NNP
cord-353633-a4pu6rlu	356	25	o	o	NN
cord-353633-a4pu6rlu	356	26	u	u	NN
cord-353633-a4pu6rlu	356	27	r	r	NN
cord-353633-a4pu6rlu	356	28	n	n	NN
cord-353633-a4pu6rlu	356	29	a	a	DT
cord-353633-a4pu6rlu	356	30	l	l	NN
cord-353633-a4pu6rlu	356	31	P	p	NN
cord-353633-a4pu6rlu	356	32	r	r	NN
cord-353633-a4pu6rlu	356	33	e	e	NN
cord-353633-a4pu6rlu	356	34	-p	-p	NN
cord-353633-a4pu6rlu	356	35	r	r	NN
cord-353633-a4pu6rlu	356	36	o	o	NN
cord-353633-a4pu6rlu	357	1	o	o	UH
cord-353633-a4pu6rlu	357	2	f	f	NNP
cord-353633-a4pu6rlu	357	3	47	47	CD
cord-353633-a4pu6rlu	357	4	increase	increase	NN
cord-353633-a4pu6rlu	357	5	ceramide	ceramide	NN
cord-353633-a4pu6rlu	357	6	degradation	degradation	NN
cord-353633-a4pu6rlu	357	7	.	.	.
cord-353633-a4pu6rlu	358	1	The	the	DT
cord-353633-a4pu6rlu	358	2	reduction	reduction	NN
cord-353633-a4pu6rlu	358	3	of	of	IN
cord-353633-a4pu6rlu	358	4	ceramide	ceramide	NN
cord-353633-a4pu6rlu	358	5	synthesis	synthesis	NN
cord-353633-a4pu6rlu	358	6	can	can	MD
cord-353633-a4pu6rlu	358	7	be	be	VB
cord-353633-a4pu6rlu	358	8	achieved	achieve	VBN
cord-353633-a4pu6rlu	358	9	by	by	IN
cord-353633-a4pu6rlu	358	10	inhibiting	inhibit	VBG
cord-353633-a4pu6rlu	358	11	relevant	relevant	JJ
cord-353633-a4pu6rlu	358	12	enzymes	enzyme	NNS
cord-353633-a4pu6rlu	358	13	(	(	-LRB-
cord-353633-a4pu6rlu	358	14	i.e.	i.e.	FW
cord-353633-a4pu6rlu	358	15	palmitoyltransferase	palmitoyltransferase	NN
cord-353633-a4pu6rlu	358	16	)	)	-RRB-
cord-353633-a4pu6rlu	358	17	but	but	CC
cord-353633-a4pu6rlu	358	18	it	-PRON-	PRP
cord-353633-a4pu6rlu	358	19	should	should	MD
cord-353633-a4pu6rlu	358	20	be	be	VB
cord-353633-a4pu6rlu	358	21	limited	limit	VBN
cord-353633-a4pu6rlu	358	22	only	only	RB
cord-353633-a4pu6rlu	358	23	to	to	IN
cord-353633-a4pu6rlu	358	24	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	358	25	ceramides	ceramide	NNS
cord-353633-a4pu6rlu	358	26	,	,	,
cord-353633-a4pu6rlu	358	27	since	since	IN
cord-353633-a4pu6rlu	358	28	global	global	JJ
cord-353633-a4pu6rlu	358	29	reduction	reduction	NN
cord-353633-a4pu6rlu	358	30	of	of	IN
cord-353633-a4pu6rlu	358	31	ceramides	ceramide	NNS
cord-353633-a4pu6rlu	358	32	can	can	MD
cord-353633-a4pu6rlu	358	33	negatively	negatively	RB
cord-353633-a4pu6rlu	358	34	affect	affect	VB
cord-353633-a4pu6rlu	358	35	nervous	nervous	JJ
cord-353633-a4pu6rlu	358	36	system	system	NN
cord-353633-a4pu6rlu	358	37	[	[	-LRB-
cord-353633-a4pu6rlu	358	38	198	198	CD
cord-353633-a4pu6rlu	358	39	]	]	-RRB-
cord-353633-a4pu6rlu	358	40	.	.	.
cord-353633-a4pu6rlu	359	1	Alternatively	alternatively	RB
cord-353633-a4pu6rlu	359	2	,	,	,
cord-353633-a4pu6rlu	359	3	lower	low	JJR
cord-353633-a4pu6rlu	359	4	ceramide	ceramide	NN
cord-353633-a4pu6rlu	359	5	synthesis	synthesis	NN
cord-353633-a4pu6rlu	359	6	can	can	MD
cord-353633-a4pu6rlu	359	7	be	be	VB
cord-353633-a4pu6rlu	359	8	achieved	achieve	VBN
cord-353633-a4pu6rlu	359	9	by	by	IN
cord-353633-a4pu6rlu	359	10	blocking	block	VBG
cord-353633-a4pu6rlu	359	11	intestinal	intestinal	JJ
cord-353633-a4pu6rlu	359	12	FXR	FXR	NNP
cord-353633-a4pu6rlu	359	13	activation	activation	NN
cord-353633-a4pu6rlu	359	14	[	[	-LRB-
cord-353633-a4pu6rlu	359	15	199	199	CD
cord-353633-a4pu6rlu	359	16	]	]	-RRB-
cord-353633-a4pu6rlu	359	17	.	.	.
cord-353633-a4pu6rlu	360	1	However	however	RB
cord-353633-a4pu6rlu	360	2	,	,	,
cord-353633-a4pu6rlu	360	3	in	in	IN
cord-353633-a4pu6rlu	360	4	that	that	DT
cord-353633-a4pu6rlu	360	5	case	case	NN
cord-353633-a4pu6rlu	360	6	,	,	,
cord-353633-a4pu6rlu	360	7	FXR	FXR	NNP
cord-353633-a4pu6rlu	360	8	blocking	blocking	NN
cord-353633-a4pu6rlu	360	9	should	should	MD
cord-353633-a4pu6rlu	360	10	be	be	VB
cord-353633-a4pu6rlu	360	11	limited	limit	VBN
cord-353633-a4pu6rlu	360	12	to	to	IN
cord-353633-a4pu6rlu	360	13	the	the	DT
cord-353633-a4pu6rlu	360	14	intestine	intestine	NN
cord-353633-a4pu6rlu	360	15	and	and	CC
cord-353633-a4pu6rlu	360	16	not	not	RB
cord-353633-a4pu6rlu	360	17	affect	affect	VB
cord-353633-a4pu6rlu	360	18	FXR	FXR	NNP
cord-353633-a4pu6rlu	360	19	activation	activation	NN
cord-353633-a4pu6rlu	360	20	in	in	IN
cord-353633-a4pu6rlu	360	21	the	the	DT
cord-353633-a4pu6rlu	360	22	liver	liver	NN
cord-353633-a4pu6rlu	360	23	which	which	WDT
cord-353633-a4pu6rlu	360	24	acts	act	VBZ
cord-353633-a4pu6rlu	360	25	beneficially	beneficially	RB
cord-353633-a4pu6rlu	360	26	.	.	.
cord-353633-a4pu6rlu	361	1	In	in	IN
cord-353633-a4pu6rlu	361	2	other	other	JJ
cord-353633-a4pu6rlu	361	3	approaches	approach	NNS
cord-353633-a4pu6rlu	361	4	,	,	,
cord-353633-a4pu6rlu	361	5	reduction	reduction	NN
cord-353633-a4pu6rlu	361	6	of	of	IN
cord-353633-a4pu6rlu	361	7	the	the	DT
cord-353633-a4pu6rlu	361	8	accumulation	accumulation	NN
cord-353633-a4pu6rlu	361	9	of	of	IN
cord-353633-a4pu6rlu	361	10	specific	specific	JJ
cord-353633-a4pu6rlu	361	11	ceramides	ceramide	NNS
cord-353633-a4pu6rlu	361	12	(	(	-LRB-
cord-353633-a4pu6rlu	361	13	i.e.	i.e.	FW
cord-353633-a4pu6rlu	361	14	C16:0	C16:0	NNP
cord-353633-a4pu6rlu	361	15	ceramide	ceramide	NN
cord-353633-a4pu6rlu	361	16	)	)	-RRB-
cord-353633-a4pu6rlu	361	17	is	be	VBZ
cord-353633-a4pu6rlu	361	18	targeted	target	VBN
cord-353633-a4pu6rlu	361	19	with	with	IN
cord-353633-a4pu6rlu	361	20	the	the	DT
cord-353633-a4pu6rlu	361	21	use	use	NN
cord-353633-a4pu6rlu	361	22	of	of	IN
cord-353633-a4pu6rlu	361	23	several	several	JJ
cord-353633-a4pu6rlu	361	24	inhibitors	inhibitor	NNS
cord-353633-a4pu6rlu	361	25	(	(	-LRB-
cord-353633-a4pu6rlu	361	26	e.g.	e.g.	RB
cord-353633-a4pu6rlu	361	27	DES-1	DES-1	NNP
cord-353633-a4pu6rlu	361	28	70	70	CD
cord-353633-a4pu6rlu	361	29	)	)	-RRB-
cord-353633-a4pu6rlu	361	30	or	or	CC
cord-353633-a4pu6rlu	361	31	degradation	degradation	NN
cord-353633-a4pu6rlu	361	32	of	of	IN
cord-353633-a4pu6rlu	361	33	ceramides	ceramide	NNS
cord-353633-a4pu6rlu	361	34	is	be	VBZ
cord-353633-a4pu6rlu	361	35	stimulated	stimulate	VBN
cord-353633-a4pu6rlu	361	36	by	by	IN
cord-353633-a4pu6rlu	361	37	enzymes	enzyme	NNS
cord-353633-a4pu6rlu	361	38	(	(	-LRB-
cord-353633-a4pu6rlu	361	39	e.g.	e.g.	RB
cord-353633-a4pu6rlu	361	40	acid	acid	JJ
cord-353633-a4pu6rlu	361	41	ceraminidase	ceraminidase	NN
cord-353633-a4pu6rlu	361	42	)	)	-RRB-
cord-353633-a4pu6rlu	361	43	.	.	.
cord-353633-a4pu6rlu	362	1	These	these	DT
cord-353633-a4pu6rlu	362	2	have	have	VBP
cord-353633-a4pu6rlu	362	3	till	till	IN
cord-353633-a4pu6rlu	362	4	now	now	RB
cord-353633-a4pu6rlu	362	5	been	be	VBN
cord-353633-a4pu6rlu	362	6	tested	test	VBN
cord-353633-a4pu6rlu	362	7	only	only	RB
cord-353633-a4pu6rlu	362	8	in	in	IN
cord-353633-a4pu6rlu	362	9	animal	animal	NN
cord-353633-a4pu6rlu	362	10	studies	study	NNS
cord-353633-a4pu6rlu	362	11	and	and	CC
cord-353633-a4pu6rlu	362	12	not	not	RB
cord-353633-a4pu6rlu	362	13	in	in	IN
cord-353633-a4pu6rlu	362	14	humans	human	NNS
cord-353633-a4pu6rlu	362	15	.	.	.
cord-353633-a4pu6rlu	363	1	Many	many	JJ
cord-353633-a4pu6rlu	363	2	treatments	treatment	NNS
cord-353633-a4pu6rlu	363	3	have	have	VBP
cord-353633-a4pu6rlu	363	4	targeted	target	VBN
cord-353633-a4pu6rlu	363	5	to	to	TO
cord-353633-a4pu6rlu	363	6	restore	restore	VB
cord-353633-a4pu6rlu	363	7	the	the	DT
cord-353633-a4pu6rlu	363	8	increased	increase	VBN
cord-353633-a4pu6rlu	363	9	ω-6	ω-6	NNP
cord-353633-a4pu6rlu	363	10	/	/	SYM
cord-353633-a4pu6rlu	363	11	ω-3	ω-3	CD
cord-353633-a4pu6rlu	363	12	ratio	ratio	NN
cord-353633-a4pu6rlu	363	13	by	by	IN
cord-353633-a4pu6rlu	363	14	ω-3	ω-3	CD
cord-353633-a4pu6rlu	363	15	supplementation	supplementation	NN
cord-353633-a4pu6rlu	363	16	.	.	.
cord-353633-a4pu6rlu	364	1	Although	although	IN
cord-353633-a4pu6rlu	364	2	the	the	DT
cord-353633-a4pu6rlu	364	3	findings	finding	NNS
cord-353633-a4pu6rlu	364	4	from	from	IN
cord-353633-a4pu6rlu	364	5	animal	animal	NN
cord-353633-a4pu6rlu	364	6	studies	study	NNS
cord-353633-a4pu6rlu	364	7	had	have	VBD
cord-353633-a4pu6rlu	364	8	been	be	VBN
cord-353633-a4pu6rlu	364	9	very	very	RB
cord-353633-a4pu6rlu	364	10	promising	promising	JJ
cord-353633-a4pu6rlu	364	11	,	,	,
cord-353633-a4pu6rlu	364	12	and	and	CC
cord-353633-a4pu6rlu	364	13	the	the	DT
cord-353633-a4pu6rlu	364	14	first	first	JJ
cord-353633-a4pu6rlu	364	15	results	result	NNS
cord-353633-a4pu6rlu	364	16	from	from	IN
cord-353633-a4pu6rlu	364	17	human	human	JJ
cord-353633-a4pu6rlu	364	18	studies	study	NNS
cord-353633-a4pu6rlu	364	19	had	have	VBD
cord-353633-a4pu6rlu	364	20	shown	show	VBN
cord-353633-a4pu6rlu	364	21	an	an	DT
cord-353633-a4pu6rlu	364	22	improvement	improvement	NN
cord-353633-a4pu6rlu	364	23	in	in	IN
cord-353633-a4pu6rlu	364	24	liver	liver	NN
cord-353633-a4pu6rlu	364	25	steatosis	steatosis	NN
cord-353633-a4pu6rlu	364	26	,	,	,
cord-353633-a4pu6rlu	364	27	later	later	JJ
cord-353633-a4pu6rlu	364	28	studies	study	NNS
cord-353633-a4pu6rlu	364	29	could	could	MD
cord-353633-a4pu6rlu	364	30	not	not	RB
cord-353633-a4pu6rlu	364	31	demonstrate	demonstrate	VB
cord-353633-a4pu6rlu	364	32	any	any	DT
cord-353633-a4pu6rlu	364	33	benefit	benefit	NN
cord-353633-a4pu6rlu	364	34	in	in	IN
cord-353633-a4pu6rlu	364	35	steatosis	steatosis	NN
cord-353633-a4pu6rlu	364	36	,	,	,
cord-353633-a4pu6rlu	364	37	necro	necro	NN
cord-353633-a4pu6rlu	364	38	-	-	HYPH
cord-353633-a4pu6rlu	364	39	inflammation	inflammation	NN
cord-353633-a4pu6rlu	364	40	or	or	CC
cord-353633-a4pu6rlu	364	41	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	364	42	in	in	IN
cord-353633-a4pu6rlu	364	43	patients	patient	NNS
cord-353633-a4pu6rlu	364	44	with	with	IN
cord-353633-a4pu6rlu	364	45	NASH	NASH	NNP
cord-353633-a4pu6rlu	364	46	[	[	-LRB-
cord-353633-a4pu6rlu	364	47	142	142	CD
cord-353633-a4pu6rlu	364	48	,	,	,
cord-353633-a4pu6rlu	364	49	[	[	-LRB-
cord-353633-a4pu6rlu	364	50	200	200	CD
cord-353633-a4pu6rlu	364	51	]	]	-RRB-
cord-353633-a4pu6rlu	364	52	[	[	-LRB-
cord-353633-a4pu6rlu	364	53	201	201	CD
cord-353633-a4pu6rlu	364	54	]	]	-RRB-
cord-353633-a4pu6rlu	364	55	[	[	-LRB-
cord-353633-a4pu6rlu	364	56	202	202	CD
cord-353633-a4pu6rlu	364	57	]	]	-RRB-
cord-353633-a4pu6rlu	364	58	.	.	.
cord-353633-a4pu6rlu	365	1	Newer	new	JJR
cord-353633-a4pu6rlu	365	2	experimental	experimental	JJ
cord-353633-a4pu6rlu	365	3	strategies	strategy	NNS
cord-353633-a4pu6rlu	365	4	are	be	VBP
cord-353633-a4pu6rlu	365	5	focusing	focus	VBG
cord-353633-a4pu6rlu	365	6	not	not	RB
cord-353633-a4pu6rlu	365	7	on	on	IN
cord-353633-a4pu6rlu	365	8	the	the	DT
cord-353633-a4pu6rlu	365	9	supplementation	supplementation	NN
cord-353633-a4pu6rlu	365	10	of	of	IN
cord-353633-a4pu6rlu	365	11	ω3	ω3	NNP
cord-353633-a4pu6rlu	365	12	but	but	CC
cord-353633-a4pu6rlu	365	13	on	on	IN
cord-353633-a4pu6rlu	365	14	restoration	restoration	NN
cord-353633-a4pu6rlu	365	15	of	of	IN
cord-353633-a4pu6rlu	365	16	the	the	DT
cord-353633-a4pu6rlu	365	17	ω-6	ω-6	NNP
cord-353633-a4pu6rlu	365	18	/	/	SYM
cord-353633-a4pu6rlu	365	19	ω-3	ω-3	CD
cord-353633-a4pu6rlu	365	20	ratio	ratio	NN
cord-353633-a4pu6rlu	365	21	with	with	IN
cord-353633-a4pu6rlu	365	22	the	the	DT
cord-353633-a4pu6rlu	365	23	use	use	NN
cord-353633-a4pu6rlu	365	24	of	of	IN
cord-353633-a4pu6rlu	365	25	ω-3	ω-3	CD
cord-353633-a4pu6rlu	365	26	desaturase	desaturase	NN
cord-353633-a4pu6rlu	365	27	that	that	WDT
cord-353633-a4pu6rlu	365	28	leads	lead	VBZ
cord-353633-a4pu6rlu	365	29	to	to	IN
cord-353633-a4pu6rlu	365	30	the	the	DT
cord-353633-a4pu6rlu	365	31	production	production	NN
cord-353633-a4pu6rlu	365	32	of	of	IN
cord-353633-a4pu6rlu	365	33	ω-3	ω-3	CD
cord-353633-a4pu6rlu	365	34	from	from	IN
cord-353633-a4pu6rlu	365	35	ω-6	ω-6	NN
cord-353633-a4pu6rlu	365	36	PUFAs	pufa	NNS
cord-353633-a4pu6rlu	365	37	,	,	,
cord-353633-a4pu6rlu	365	38	showing	show	VBG
cord-353633-a4pu6rlu	365	39	beneficial	beneficial	JJ
cord-353633-a4pu6rlu	365	40	effects	effect	NNS
cord-353633-a4pu6rlu	365	41	in	in	IN
cord-353633-a4pu6rlu	365	42	steatosis	steatosis	NN
cord-353633-a4pu6rlu	365	43	and	and	CC
cord-353633-a4pu6rlu	365	44	necro	necro	NN
cord-353633-a4pu6rlu	365	45	-	-	HYPH
cord-353633-a4pu6rlu	365	46	inflammation	inflammation	NN
cord-353633-a4pu6rlu	365	47	in	in	IN
cord-353633-a4pu6rlu	365	48	animal	animal	NN
cord-353633-a4pu6rlu	365	49	studies	study	NNS
cord-353633-a4pu6rlu	365	50	[	[	-LRB-
cord-353633-a4pu6rlu	365	51	203	203	CD
cord-353633-a4pu6rlu	365	52	]	]	-RRB-
cord-353633-a4pu6rlu	365	53	.	.	.
cord-353633-a4pu6rlu	366	1	Finally	finally	RB
cord-353633-a4pu6rlu	366	2	,	,	,
cord-353633-a4pu6rlu	366	3	different	different	JJ
cord-353633-a4pu6rlu	366	4	experimental	experimental	JJ
cord-353633-a4pu6rlu	366	5	approaches	approach	NNS
cord-353633-a4pu6rlu	366	6	are	be	VBP
cord-353633-a4pu6rlu	366	7	aiming	aim	VBG
cord-353633-a4pu6rlu	366	8	to	to	TO
cord-353633-a4pu6rlu	366	9	decrease	decrease	VB
cord-353633-a4pu6rlu	366	10	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	366	11	eicosanoids	eicosanoid	NNS
cord-353633-a4pu6rlu	366	12	and	and	CC
cord-353633-a4pu6rlu	366	13	increase	increase	VB
cord-353633-a4pu6rlu	366	14	the	the	DT
cord-353633-a4pu6rlu	366	15	concentrations	concentration	NNS
cord-353633-a4pu6rlu	366	16	of	of	IN
cord-353633-a4pu6rlu	366	17	SPMs	spm	NNS
cord-353633-a4pu6rlu	366	18	.	.	.
cord-353633-a4pu6rlu	367	1	Specifically	specifically	RB
cord-353633-a4pu6rlu	367	2	,	,	,
cord-353633-a4pu6rlu	367	3	some	some	DT
cord-353633-a4pu6rlu	367	4	of	of	IN
cord-353633-a4pu6rlu	367	5	them	-PRON-	PRP
cord-353633-a4pu6rlu	367	6	are	be	VBP
cord-353633-a4pu6rlu	367	7	targeting	target	VBG
cord-353633-a4pu6rlu	367	8	the	the	DT
cord-353633-a4pu6rlu	367	9	inhibition	inhibition	NN
cord-353633-a4pu6rlu	367	10	of	of	IN
cord-353633-a4pu6rlu	367	11	PLA2α	PLA2α	NNP
cord-353633-a4pu6rlu	367	12	enzyme	enzyme	NN
cord-353633-a4pu6rlu	367	13	that	that	WDT
cord-353633-a4pu6rlu	367	14	catalyzes	catalyze	VBZ
cord-353633-a4pu6rlu	367	15	the	the	DT
cord-353633-a4pu6rlu	367	16	cascade	cascade	NN
cord-353633-a4pu6rlu	367	17	leading	lead	VBG
cord-353633-a4pu6rlu	367	18	to	to	IN
cord-353633-a4pu6rlu	367	19	AA	AA	NNP
cord-353633-a4pu6rlu	367	20	and	and	CC
cord-353633-a4pu6rlu	367	21	lysophospholipids	lysophospholipids	NNP
cord-353633-a4pu6rlu	367	22	generation	generation	NN
cord-353633-a4pu6rlu	367	23	,	,	,
cord-353633-a4pu6rlu	367	24	showing	show	VBG
cord-353633-a4pu6rlu	367	25	promising	promising	JJ
cord-353633-a4pu6rlu	367	26	results	result	NNS
cord-353633-a4pu6rlu	367	27	in	in	IN
cord-353633-a4pu6rlu	367	28	animal	animal	NN
cord-353633-a4pu6rlu	367	29	studies	study	NNS
cord-353633-a4pu6rlu	367	30	[	[	-LRB-
cord-353633-a4pu6rlu	367	31	197	197	CD
cord-353633-a4pu6rlu	367	32	,	,	,
cord-353633-a4pu6rlu	367	33	204	204	CD
cord-353633-a4pu6rlu	367	34	]	]	-RRB-
cord-353633-a4pu6rlu	367	35	.	.	.
cord-353633-a4pu6rlu	368	1	Others	other	NNS
cord-353633-a4pu6rlu	368	2	are	be	VBP
cord-353633-a4pu6rlu	368	3	targeting	target	VBG
cord-353633-a4pu6rlu	368	4	J	J	NNP
cord-353633-a4pu6rlu	368	5	o	o	NN
cord-353633-a4pu6rlu	368	6	u	u	NN
cord-353633-a4pu6rlu	368	7	r	r	NN
cord-353633-a4pu6rlu	368	8	n	n	NN
cord-353633-a4pu6rlu	368	9	a	a	DT
cord-353633-a4pu6rlu	368	10	l	l	NN
cord-353633-a4pu6rlu	368	11	P	p	NN
cord-353633-a4pu6rlu	368	12	r	r	NN
cord-353633-a4pu6rlu	368	13	e	e	NN
cord-353633-a4pu6rlu	369	1	-p	-p	:
cord-353633-a4pu6rlu	370	1	r	r	NN
cord-353633-a4pu6rlu	370	2	o	o	NN
cord-353633-a4pu6rlu	370	3	o	o	NN
cord-353633-a4pu6rlu	370	4	f	f	NN
cord-353633-a4pu6rlu	370	5	48	48	CD
cord-353633-a4pu6rlu	370	6	the	the	DT
cord-353633-a4pu6rlu	370	7	production	production	NN
cord-353633-a4pu6rlu	370	8	of	of	IN
cord-353633-a4pu6rlu	370	9	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	370	10	lipids	lipid	NNS
cord-353633-a4pu6rlu	370	11	by	by	IN
cord-353633-a4pu6rlu	370	12	inhibiting	inhibit	VBG
cord-353633-a4pu6rlu	370	13	the	the	DT
cord-353633-a4pu6rlu	370	14	enzyme	enzyme	NN
cord-353633-a4pu6rlu	370	15	5-LOX	5-lox	CD
cord-353633-a4pu6rlu	370	16	[	[	-LRB-
cord-353633-a4pu6rlu	370	17	205	205	CD
cord-353633-a4pu6rlu	370	18	,	,	,
cord-353633-a4pu6rlu	370	19	206	206	CD
cord-353633-a4pu6rlu	370	20	]	]	-RRB-
cord-353633-a4pu6rlu	370	21	which	which	WDT
cord-353633-a4pu6rlu	370	22	catalyzes	catalyze	VBZ
cord-353633-a4pu6rlu	370	23	the	the	DT
cord-353633-a4pu6rlu	370	24	lipooxygenation	lipooxygenation	NN
cord-353633-a4pu6rlu	370	25	of	of	IN
cord-353633-a4pu6rlu	370	26	AA	AA	NNP
cord-353633-a4pu6rlu	370	27	to	to	IN
cord-353633-a4pu6rlu	370	28	leukotriene	leukotriene	NN
cord-353633-a4pu6rlu	370	29	lipids	lipid	NNS
cord-353633-a4pu6rlu	370	30	or	or	CC
cord-353633-a4pu6rlu	370	31	they	-PRON-	PRP
cord-353633-a4pu6rlu	370	32	aim	aim	VBP
cord-353633-a4pu6rlu	370	33	to	to	TO
cord-353633-a4pu6rlu	370	34	block	block	VB
cord-353633-a4pu6rlu	370	35	the	the	DT
cord-353633-a4pu6rlu	370	36	binding	binding	NN
cord-353633-a4pu6rlu	370	37	of	of	IN
cord-353633-a4pu6rlu	370	38	leukotrienes	leukotriene	NNS
cord-353633-a4pu6rlu	370	39	to	to	IN
cord-353633-a4pu6rlu	370	40	their	-PRON-	PRP$
cord-353633-a4pu6rlu	370	41	receptors	receptor	NNS
cord-353633-a4pu6rlu	370	42	[	[	-LRB-
cord-353633-a4pu6rlu	370	43	207	207	CD
cord-353633-a4pu6rlu	370	44	]	]	-RRB-
cord-353633-a4pu6rlu	370	45	.	.	.
cord-353633-a4pu6rlu	371	1	The	the	DT
cord-353633-a4pu6rlu	371	2	5-LOX	5-lox	CD
cord-353633-a4pu6rlu	371	3	inhibitor	inhibitor	NN
cord-353633-a4pu6rlu	371	4	tipelukast	tipelukast	NN
cord-353633-a4pu6rlu	371	5	has	have	VBZ
cord-353633-a4pu6rlu	371	6	been	be	VBN
cord-353633-a4pu6rlu	371	7	approved	approve	VBN
cord-353633-a4pu6rlu	371	8	by	by	IN
cord-353633-a4pu6rlu	371	9	FDA	FDA	NNP
cord-353633-a4pu6rlu	371	10	for	for	IN
cord-353633-a4pu6rlu	371	11	a	a	DT
cord-353633-a4pu6rlu	371	12	phase	phase	NN
cord-353633-a4pu6rlu	371	13	IIa	IIa	NNP
cord-353633-a4pu6rlu	371	14	clinical	clinical	JJ
cord-353633-a4pu6rlu	371	15	trial	trial	NN
cord-353633-a4pu6rlu	371	16	.	.	.
cord-353633-a4pu6rlu	372	1	Finally	finally	RB
cord-353633-a4pu6rlu	372	2	,	,	,
cord-353633-a4pu6rlu	372	3	other	other	JJ
cord-353633-a4pu6rlu	372	4	approaches	approach	NNS
cord-353633-a4pu6rlu	372	5	are	be	VBP
cord-353633-a4pu6rlu	372	6	aiming	aim	VBG
cord-353633-a4pu6rlu	372	7	to	to	TO
cord-353633-a4pu6rlu	372	8	increase	increase	VB
cord-353633-a4pu6rlu	372	9	the	the	DT
cord-353633-a4pu6rlu	372	10	SPMs	spm	NNS
cord-353633-a4pu6rlu	372	11	RvD1	rvd1	NN
cord-353633-a4pu6rlu	372	12	,	,	,
cord-353633-a4pu6rlu	372	13	RvE1	rve1	NN
cord-353633-a4pu6rlu	372	14	,	,	,
cord-353633-a4pu6rlu	372	15	protectin	protectin	NNP
cord-353633-a4pu6rlu	372	16	DX	DX	NNP
cord-353633-a4pu6rlu	372	17	and	and	CC
cord-353633-a4pu6rlu	372	18	maresin-1	maresin-1	NNP
cord-353633-a4pu6rlu	372	19	leading	lead	VBG
cord-353633-a4pu6rlu	372	20	to	to	IN
cord-353633-a4pu6rlu	372	21	robust	robust	JJ
cord-353633-a4pu6rlu	372	22	improvement	improvement	NN
cord-353633-a4pu6rlu	372	23	of	of	IN
cord-353633-a4pu6rlu	372	24	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	372	25	in	in	IN
cord-353633-a4pu6rlu	372	26	animal	animal	NN
cord-353633-a4pu6rlu	372	27	models	model	NNS
cord-353633-a4pu6rlu	372	28	of	of	IN
cord-353633-a4pu6rlu	372	29	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	372	30	[	[	-LRB-
cord-353633-a4pu6rlu	372	31	164	164	CD
cord-353633-a4pu6rlu	372	32	,	,	,
cord-353633-a4pu6rlu	372	33	208	208	CD
cord-353633-a4pu6rlu	372	34	,	,	,
cord-353633-a4pu6rlu	372	35	209	209	CD
cord-353633-a4pu6rlu	372	36	]	]	-RRB-
cord-353633-a4pu6rlu	372	37	.	.	.
cord-353633-a4pu6rlu	373	1	Given	give	VBN
cord-353633-a4pu6rlu	373	2	that	that	IN
cord-353633-a4pu6rlu	373	3	SPMs	spm	NNS
cord-353633-a4pu6rlu	373	4	are	be	VBP
cord-353633-a4pu6rlu	373	5	rapidly	rapidly	RB
cord-353633-a4pu6rlu	373	6	inactivated	inactivate	VBN
cord-353633-a4pu6rlu	373	7	by	by	IN
cord-353633-a4pu6rlu	373	8	oxidoreductases	oxidoreductase	NNS
cord-353633-a4pu6rlu	373	9	and	and	CC
cord-353633-a4pu6rlu	373	10	that	that	IN
cord-353633-a4pu6rlu	373	11	SPM	SPM	NNP
cord-353633-a4pu6rlu	373	12	receptors	receptor	NNS
cord-353633-a4pu6rlu	373	13	are	be	VBP
cord-353633-a4pu6rlu	373	14	downregulated	downregulate	VBN
cord-353633-a4pu6rlu	373	15	in	in	IN
cord-353633-a4pu6rlu	373	16	obesity	obesity	NN
cord-353633-a4pu6rlu	373	17	,	,	,
cord-353633-a4pu6rlu	373	18	recent	recent	JJ
cord-353633-a4pu6rlu	373	19	efforts	effort	NNS
cord-353633-a4pu6rlu	373	20	are	be	VBP
cord-353633-a4pu6rlu	373	21	also	also	RB
cord-353633-a4pu6rlu	373	22	focusing	focus	VBG
cord-353633-a4pu6rlu	373	23	on	on	IN
cord-353633-a4pu6rlu	373	24	improving	improve	VBG
cord-353633-a4pu6rlu	373	25	the	the	DT
cord-353633-a4pu6rlu	373	26	pharmacologic	pharmacologic	JJ
cord-353633-a4pu6rlu	373	27	properties	property	NNS
cord-353633-a4pu6rlu	373	28	of	of	IN
cord-353633-a4pu6rlu	373	29	them	-PRON-	PRP
cord-353633-a4pu6rlu	373	30	by	by	IN
cord-353633-a4pu6rlu	373	31	creating	create	VBG
cord-353633-a4pu6rlu	373	32	either	either	CC
cord-353633-a4pu6rlu	373	33	resistant	resistant	JJ
cord-353633-a4pu6rlu	373	34	to	to	IN
cord-353633-a4pu6rlu	373	35	deactivation	deactivation	NN
cord-353633-a4pu6rlu	373	36	analogues	analogue	NNS
cord-353633-a4pu6rlu	373	37	[	[	-LRB-
cord-353633-a4pu6rlu	373	38	210	210	CD
cord-353633-a4pu6rlu	373	39	]	]	-RRB-
cord-353633-a4pu6rlu	373	40	or	or	CC
cord-353633-a4pu6rlu	373	41	by	by	IN
cord-353633-a4pu6rlu	373	42	enhancing	enhance	VBG
cord-353633-a4pu6rlu	373	43	their	-PRON-	PRP$
cord-353633-a4pu6rlu	373	44	delivery	delivery	NN
cord-353633-a4pu6rlu	373	45	on	on	IN
cord-353633-a4pu6rlu	373	46	their	-PRON-	PRP$
cord-353633-a4pu6rlu	373	47	site	site	NN
cord-353633-a4pu6rlu	373	48	of	of	IN
cord-353633-a4pu6rlu	373	49	function	function	NN
cord-353633-a4pu6rlu	373	50	.	.	.
cord-353633-a4pu6rlu	374	1	Altogether	altogether	RB
cord-353633-a4pu6rlu	374	2	,	,	,
cord-353633-a4pu6rlu	374	3	most	most	JJS
cord-353633-a4pu6rlu	374	4	drugs	drug	NNS
cord-353633-a4pu6rlu	374	5	in	in	IN
cord-353633-a4pu6rlu	374	6	on	on	RB
cord-353633-a4pu6rlu	374	7	-	-	HYPH
cord-353633-a4pu6rlu	374	8	going	go	VBG
cord-353633-a4pu6rlu	374	9	clinical	clinical	JJ
cord-353633-a4pu6rlu	374	10	trials	trial	NNS
cord-353633-a4pu6rlu	374	11	are	be	VBP
cord-353633-a4pu6rlu	374	12	targeting	target	VBG
cord-353633-a4pu6rlu	374	13	,	,	,
cord-353633-a4pu6rlu	374	14	among	among	IN
cord-353633-a4pu6rlu	374	15	other	other	JJ
cord-353633-a4pu6rlu	374	16	mechanisms	mechanism	NNS
cord-353633-a4pu6rlu	374	17	,	,	,
cord-353633-a4pu6rlu	374	18	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	374	19	lipidome	lipidome	NN
cord-353633-a4pu6rlu	374	20	in	in	IN
cord-353633-a4pu6rlu	374	21	order	order	NN
cord-353633-a4pu6rlu	374	22	to	to	TO
cord-353633-a4pu6rlu	374	23	improve	improve	VB
cord-353633-a4pu6rlu	374	24	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	374	25	.	.	.
cord-353633-a4pu6rlu	375	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	375	2	,	,	,
cord-353633-a4pu6rlu	375	3	there	there	EX
cord-353633-a4pu6rlu	375	4	is	be	VBZ
cord-353633-a4pu6rlu	375	5	a	a	DT
cord-353633-a4pu6rlu	375	6	significant	significant	JJ
cord-353633-a4pu6rlu	375	7	number	number	NN
cord-353633-a4pu6rlu	375	8	of	of	IN
cord-353633-a4pu6rlu	375	9	medications	medication	NNS
cord-353633-a4pu6rlu	375	10	that	that	WDT
cord-353633-a4pu6rlu	375	11	have	have	VBP
cord-353633-a4pu6rlu	375	12	shown	show	VBN
cord-353633-a4pu6rlu	375	13	beneficial	beneficial	JJ
cord-353633-a4pu6rlu	375	14	effects	effect	NNS
cord-353633-a4pu6rlu	375	15	on	on	IN
cord-353633-a4pu6rlu	375	16	animal	animal	NN
cord-353633-a4pu6rlu	375	17	models	model	NNS
cord-353633-a4pu6rlu	375	18	of	of	IN
cord-353633-a4pu6rlu	375	19	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	375	20	by	by	IN
cord-353633-a4pu6rlu	375	21	improving	improve	VBG
cord-353633-a4pu6rlu	375	22	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	375	23	metabolome	metabolome	NNP
cord-353633-a4pu6rlu	375	24	/	/	SYM
cord-353633-a4pu6rlu	375	25	lipidome	lipidome	NNP
cord-353633-a4pu6rlu	375	26	and	and	CC
cord-353633-a4pu6rlu	375	27	remain	remain	VBP
cord-353633-a4pu6rlu	375	28	to	to	TO
cord-353633-a4pu6rlu	375	29	be	be	VB
cord-353633-a4pu6rlu	375	30	further	further	RB
cord-353633-a4pu6rlu	375	31	clinically	clinically	RB
cord-353633-a4pu6rlu	375	32	tested	test	VBN
cord-353633-a4pu6rlu	375	33	.	.	.
cord-353633-a4pu6rlu	376	1	Metabolomics	Metabolomics	NNP
cord-353633-a4pu6rlu	376	2	/	/	SYM
cord-353633-a4pu6rlu	376	3	Lipidomics	Lipidomics	NNPS
cord-353633-a4pu6rlu	376	4	are	be	VBP
cord-353633-a4pu6rlu	376	5	one	one	CD
cord-353633-a4pu6rlu	376	6	of	of	IN
cord-353633-a4pu6rlu	376	7	the	the	DT
cord-353633-a4pu6rlu	376	8	most	most	RBS
cord-353633-a4pu6rlu	376	9	investigated	investigate	VBN
cord-353633-a4pu6rlu	376	10	omics	omic	NNS
cord-353633-a4pu6rlu	376	11	in	in	IN
cord-353633-a4pu6rlu	376	12	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	376	13	.	.	.
cord-353633-a4pu6rlu	376	14	 	 	_SP
cord-353633-a4pu6rlu	377	1	Glycomics	Glycomics	NNP
cord-353633-a4pu6rlu	377	2	refers	refer	VBZ
cord-353633-a4pu6rlu	377	3	to	to	IN
cord-353633-a4pu6rlu	377	4	the	the	DT
cord-353633-a4pu6rlu	377	5	comprehensive	comprehensive	JJ
cord-353633-a4pu6rlu	377	6	investigation	investigation	NN
cord-353633-a4pu6rlu	377	7	of	of	IN
cord-353633-a4pu6rlu	377	8	glycome	glycome	NNP
cord-353633-a4pu6rlu	377	9	,	,	,
cord-353633-a4pu6rlu	377	10	i.e.	i.e.	FW
cord-353633-a4pu6rlu	377	11	of	of	IN
cord-353633-a4pu6rlu	377	12	glycan	glycan	NN
cord-353633-a4pu6rlu	377	13	structures	structure	NNS
cord-353633-a4pu6rlu	377	14	that	that	WDT
cord-353633-a4pu6rlu	377	15	circulate	circulate	VBP
cord-353633-a4pu6rlu	377	16	either	either	CC
cord-353633-a4pu6rlu	377	17	as	as	IN
cord-353633-a4pu6rlu	377	18	free	free	JJ
cord-353633-a4pu6rlu	377	19	glycans	glycan	NNS
cord-353633-a4pu6rlu	377	20	or	or	CC
cord-353633-a4pu6rlu	377	21	they	-PRON-	PRP
cord-353633-a4pu6rlu	377	22	are	be	VBP
cord-353633-a4pu6rlu	377	23	bound	bind	VBN
cord-353633-a4pu6rlu	377	24	to	to	IN
cord-353633-a4pu6rlu	377	25	proteins	protein	NNS
cord-353633-a4pu6rlu	377	26	(	(	-LRB-
cord-353633-a4pu6rlu	377	27	glycoproteins	glycoprotein	NNS
cord-353633-a4pu6rlu	377	28	)	)	-RRB-
cord-353633-a4pu6rlu	377	29	,	,	,
cord-353633-a4pu6rlu	377	30	lipids	lipid	NNS
cord-353633-a4pu6rlu	377	31	(	(	-LRB-
cord-353633-a4pu6rlu	377	32	glycolipids	glycolipid	NNS
cord-353633-a4pu6rlu	377	33	)	)	-RRB-
cord-353633-a4pu6rlu	377	34	or	or	CC
cord-353633-a4pu6rlu	377	35	phospholipids	phospholipid	NNS
cord-353633-a4pu6rlu	377	36	(	(	-LRB-
cord-353633-a4pu6rlu	377	37	glycophospholipids	glycophospholipid	NNS
cord-353633-a4pu6rlu	377	38	)	)	-RRB-
cord-353633-a4pu6rlu	377	39	.	.	.
cord-353633-a4pu6rlu	378	1	Glycome	Glycome	NNP
cord-353633-a4pu6rlu	378	2	is	be	VBZ
cord-353633-a4pu6rlu	378	3	highly	highly	RB
cord-353633-a4pu6rlu	378	4	dynamic	dynamic	JJ
cord-353633-a4pu6rlu	378	5	as	as	IN
cord-353633-a4pu6rlu	378	6	it	-PRON-	PRP
cord-353633-a4pu6rlu	378	7	is	be	VBZ
cord-353633-a4pu6rlu	378	8	affected	affect	VBN
cord-353633-a4pu6rlu	378	9	by	by	IN
cord-353633-a4pu6rlu	378	10	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	378	11	,	,	,
cord-353633-a4pu6rlu	378	12	proteome	proteome	NN
cord-353633-a4pu6rlu	378	13	,	,	,
cord-353633-a4pu6rlu	378	14	environmental	environmental	JJ
cord-353633-a4pu6rlu	378	15	factors	factor	NNS
cord-353633-a4pu6rlu	378	16	(	(	-LRB-
cord-353633-a4pu6rlu	378	17	nutrition	nutrition	NN
cord-353633-a4pu6rlu	378	18	)	)	-RRB-
cord-353633-a4pu6rlu	378	19	and	and	CC
cord-353633-a4pu6rlu	378	20	cellular	cellular	JJ
cord-353633-a4pu6rlu	378	21	secretory	secretory	JJ
cord-353633-a4pu6rlu	378	22	machinery	machinery	NN
cord-353633-a4pu6rlu	378	23	[	[	-LRB-
cord-353633-a4pu6rlu	378	24	125	125	CD
cord-353633-a4pu6rlu	378	25	,	,	,
cord-353633-a4pu6rlu	378	26	211	211	CD
cord-353633-a4pu6rlu	378	27	]	]	-RRB-
cord-353633-a4pu6rlu	378	28	.	.	.
cord-353633-a4pu6rlu	379	1	Glycans	glycan	NNS
cord-353633-a4pu6rlu	379	2	can	can	MD
cord-353633-a4pu6rlu	379	3	affect	affect	VB
cord-353633-a4pu6rlu	379	4	protein	protein	NN
cord-353633-a4pu6rlu	379	5	morphology	morphology	NN
cord-353633-a4pu6rlu	379	6	and	and	CC
cord-353633-a4pu6rlu	379	7	interaction	interaction	NN
cord-353633-a4pu6rlu	379	8	with	with	IN
cord-353633-a4pu6rlu	379	9	other	other	JJ
cord-353633-a4pu6rlu	379	10	proteins	protein	NNS
cord-353633-a4pu6rlu	379	11	as	as	RB
cord-353633-a4pu6rlu	379	12	well	well	RB
cord-353633-a4pu6rlu	379	13	as	as	IN
cord-353633-a4pu6rlu	379	14	regulate	regulate	VB
cord-353633-a4pu6rlu	379	15	nutrient	nutrient	NN
cord-353633-a4pu6rlu	379	16	storage	storage	NN
cord-353633-a4pu6rlu	379	17	and	and	CC
cord-353633-a4pu6rlu	379	18	sequestration	sequestration	NN
cord-353633-a4pu6rlu	379	19	[	[	-LRB-
cord-353633-a4pu6rlu	379	20	212	212	CD
cord-353633-a4pu6rlu	379	21	]	]	-RRB-
cord-353633-a4pu6rlu	379	22	.	.	.
cord-353633-a4pu6rlu	380	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	380	2	,	,	,
cord-353633-a4pu6rlu	380	3	they	-PRON-	PRP
cord-353633-a4pu6rlu	380	4	can	can	MD
cord-353633-a4pu6rlu	380	5	protect	protect	VB
cord-353633-a4pu6rlu	380	6	cell	cell	NN
cord-353633-a4pu6rlu	380	7	stability	stability	NN
cord-353633-a4pu6rlu	380	8	and	and	CC
cord-353633-a4pu6rlu	380	9	facilitate	facilitate	VB
cord-353633-a4pu6rlu	380	10	cell	cell	NN
cord-353633-a4pu6rlu	380	11	to	to	IN
cord-353633-a4pu6rlu	380	12	cell	cell	NN
cord-353633-a4pu6rlu	380	13	interactions	interaction	NNS
cord-353633-a4pu6rlu	380	14	[	[	-LRB-
cord-353633-a4pu6rlu	380	15	212	212	CD
cord-353633-a4pu6rlu	380	16	]	]	-RRB-
cord-353633-a4pu6rlu	380	17	.	.	.
cord-353633-a4pu6rlu	381	1	Glycosylation	glycosylation	NN
cord-353633-a4pu6rlu	381	2	is	be	VBZ
cord-353633-a4pu6rlu	381	3	the	the	DT
cord-353633-a4pu6rlu	381	4	process	process	NN
cord-353633-a4pu6rlu	381	5	of	of	IN
cord-353633-a4pu6rlu	381	6	the	the	DT
cord-353633-a4pu6rlu	381	7	formation	formation	NN
cord-353633-a4pu6rlu	381	8	of	of	IN
cord-353633-a4pu6rlu	381	9	the	the	DT
cord-353633-a4pu6rlu	381	10	glycoconjugates	glycoconjugate	NNS
cord-353633-a4pu6rlu	381	11	(	(	-LRB-
cord-353633-a4pu6rlu	381	12	glycoproteins	glycoprotein	NNS
cord-353633-a4pu6rlu	381	13	or	or	CC
cord-353633-a4pu6rlu	381	14	glycolipids	glycolipid	NNS
cord-353633-a4pu6rlu	381	15	)	)	-RRB-
cord-353633-a4pu6rlu	381	16	[	[	-LRB-
cord-353633-a4pu6rlu	381	17	213	213	CD
cord-353633-a4pu6rlu	381	18	]	]	-RRB-
cord-353633-a4pu6rlu	381	19	which	which	WDT
cord-353633-a4pu6rlu	381	20	can	can	MD
cord-353633-a4pu6rlu	381	21	happen	happen	VB
cord-353633-a4pu6rlu	381	22	both	both	CC
cord-353633-a4pu6rlu	381	23	intra	intra	JJ
cord-353633-a4pu6rlu	381	24	-	-	:
cord-353633-a4pu6rlu	381	25	and	and	CC
cord-353633-a4pu6rlu	381	26	extracellularly	extracellularly	RB
cord-353633-a4pu6rlu	381	27	.	.	.
cord-353633-a4pu6rlu	382	1	In	in	IN
cord-353633-a4pu6rlu	382	2	the	the	DT
cord-353633-a4pu6rlu	382	3	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	382	4	glycosylation	glycosylation	NN
cord-353633-a4pu6rlu	382	5	,	,	,
cord-353633-a4pu6rlu	382	6	enzymes	enzyme	NNS
cord-353633-a4pu6rlu	382	7	secreted	secrete	VBN
cord-353633-a4pu6rlu	382	8	mainly	mainly	RB
cord-353633-a4pu6rlu	383	1	J	J	NNP
cord-353633-a4pu6rlu	383	2	o	o	NN
cord-353633-a4pu6rlu	383	3	u	u	NN
cord-353633-a4pu6rlu	383	4	r	r	NN
cord-353633-a4pu6rlu	383	5	n	n	NN
cord-353633-a4pu6rlu	383	6	a	a	DT
cord-353633-a4pu6rlu	383	7	l	l	NN
cord-353633-a4pu6rlu	383	8	P	p	NN
cord-353633-a4pu6rlu	383	9	r	r	NN
cord-353633-a4pu6rlu	383	10	e	e	NN
cord-353633-a4pu6rlu	384	1	-p	-p	:
cord-353633-a4pu6rlu	385	1	r	r	NN
cord-353633-a4pu6rlu	385	2	o	o	NN
cord-353633-a4pu6rlu	385	3	o	o	NN
cord-353633-a4pu6rlu	385	4	f	f	NN
cord-353633-a4pu6rlu	385	5	50	50	CD
cord-353633-a4pu6rlu	385	6	from	from	IN
cord-353633-a4pu6rlu	385	7	liver	liver	NN
cord-353633-a4pu6rlu	385	8	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	385	9	and	and	CC
cord-353633-a4pu6rlu	385	10	platelets	platelet	NNS
cord-353633-a4pu6rlu	385	11	(	(	-LRB-
cord-353633-a4pu6rlu	385	12	i.e.	i.e.	FW
cord-353633-a4pu6rlu	385	13	glycosyltransferases	glycosyltransferases	NNP
cord-353633-a4pu6rlu	385	14	)	)	-RRB-
cord-353633-a4pu6rlu	385	15	are	be	VBP
cord-353633-a4pu6rlu	385	16	involved	involve	VBN
cord-353633-a4pu6rlu	385	17	[	[	-LRB-
cord-353633-a4pu6rlu	385	18	213	213	CD
cord-353633-a4pu6rlu	385	19	]	]	-RRB-
cord-353633-a4pu6rlu	385	20	.	.	.
cord-353633-a4pu6rlu	386	1	Changes	change	NNS
cord-353633-a4pu6rlu	386	2	in	in	IN
cord-353633-a4pu6rlu	386	3	glycan	glycan	NN
cord-353633-a4pu6rlu	386	4	profile	profile	NN
cord-353633-a4pu6rlu	386	5	have	have	VBP
cord-353633-a4pu6rlu	386	6	been	be	VBN
cord-353633-a4pu6rlu	386	7	observed	observe	VBN
cord-353633-a4pu6rlu	386	8	in	in	IN
cord-353633-a4pu6rlu	386	9	numerous	numerous	JJ
cord-353633-a4pu6rlu	386	10	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	386	11	diseases	disease	NNS
cord-353633-a4pu6rlu	386	12	and	and	CC
cord-353633-a4pu6rlu	386	13	in	in	IN
cord-353633-a4pu6rlu	386	14	different	different	JJ
cord-353633-a4pu6rlu	386	15	types	type	NNS
cord-353633-a4pu6rlu	386	16	of	of	IN
cord-353633-a4pu6rlu	386	17	cancer	cancer	NN
cord-353633-a4pu6rlu	386	18	and	and	CC
cord-353633-a4pu6rlu	386	19	have	have	VBP
cord-353633-a4pu6rlu	386	20	been	be	VBN
cord-353633-a4pu6rlu	386	21	often	often	RB
cord-353633-a4pu6rlu	386	22	linked	link	VBN
cord-353633-a4pu6rlu	386	23	causally	causally	RB
cord-353633-a4pu6rlu	386	24	with	with	IN
cord-353633-a4pu6rlu	386	25	the	the	DT
cord-353633-a4pu6rlu	386	26	pathogenesis	pathogenesis	NN
cord-353633-a4pu6rlu	386	27	and	and	CC
cord-353633-a4pu6rlu	386	28	progression	progression	NN
cord-353633-a4pu6rlu	386	29	of	of	IN
cord-353633-a4pu6rlu	386	30	these	these	DT
cord-353633-a4pu6rlu	386	31	diseases	disease	NNS
cord-353633-a4pu6rlu	386	32	[	[	-LRB-
cord-353633-a4pu6rlu	386	33	213	213	CD
cord-353633-a4pu6rlu	386	34	]	]	-RRB-
cord-353633-a4pu6rlu	386	35	[	[	-LRB-
cord-353633-a4pu6rlu	386	36	214	214	CD
cord-353633-a4pu6rlu	386	37	]	]	-RRB-
cord-353633-a4pu6rlu	386	38	[	[	-LRB-
cord-353633-a4pu6rlu	386	39	215	215	CD
cord-353633-a4pu6rlu	386	40	]	]	-RRB-
cord-353633-a4pu6rlu	386	41	.	.	.
cord-353633-a4pu6rlu	387	1	In	in	IN
cord-353633-a4pu6rlu	387	2	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	387	3	,	,	,
cord-353633-a4pu6rlu	387	4	few	few	JJ
cord-353633-a4pu6rlu	387	5	glycomic	glycomic	JJ
cord-353633-a4pu6rlu	387	6	studies	study	NNS
cord-353633-a4pu6rlu	387	7	have	have	VBP
cord-353633-a4pu6rlu	387	8	been	be	VBN
cord-353633-a4pu6rlu	387	9	performed	perform	VBN
cord-353633-a4pu6rlu	387	10	so	so	RB
cord-353633-a4pu6rlu	387	11	far	far	RB
cord-353633-a4pu6rlu	387	12	(	(	-LRB-
cord-353633-a4pu6rlu	387	13	Table	table	NN
cord-353633-a4pu6rlu	387	14	5	5	CD
cord-353633-a4pu6rlu	387	15	)	)	-RRB-
cord-353633-a4pu6rlu	387	16	.	.	.
cord-353633-a4pu6rlu	388	1	These	these	DT
cord-353633-a4pu6rlu	388	2	have	have	VBP
cord-353633-a4pu6rlu	388	3	either	either	CC
cord-353633-a4pu6rlu	388	4	aimed	aim	VBN
cord-353633-a4pu6rlu	388	5	to	to	TO
cord-353633-a4pu6rlu	388	6	assess	assess	VB
cord-353633-a4pu6rlu	388	7	the	the	DT
cord-353633-a4pu6rlu	388	8	circulating	circulate	VBG
cord-353633-a4pu6rlu	388	9	glycome	glycome	NN
cord-353633-a4pu6rlu	388	10	in	in	IN
cord-353633-a4pu6rlu	388	11	untargeted	untargeted	JJ
cord-353633-a4pu6rlu	388	12	approaches	approach	NNS
cord-353633-a4pu6rlu	388	13	or	or	CC
cord-353633-a4pu6rlu	388	14	they	-PRON-	PRP
cord-353633-a4pu6rlu	388	15	have	have	VBP
cord-353633-a4pu6rlu	388	16	focused	focus	VBN
cord-353633-a4pu6rlu	388	17	on	on	IN
cord-353633-a4pu6rlu	388	18	the	the	DT
cord-353633-a4pu6rlu	388	19	identification	identification	NN
cord-353633-a4pu6rlu	388	20	of	of	IN
cord-353633-a4pu6rlu	388	21	glycans	glycan	NNS
cord-353633-a4pu6rlu	388	22	related	relate	VBN
cord-353633-a4pu6rlu	388	23	to	to	IN
cord-353633-a4pu6rlu	388	24	specific	specific	JJ
cord-353633-a4pu6rlu	388	25	proteins	protein	NNS
cord-353633-a4pu6rlu	388	26	(	(	-LRB-
cord-353633-a4pu6rlu	388	27	i.e.	i.e.	FW
cord-353633-a4pu6rlu	388	28	haptoglobin	haptoglobin	NN
cord-353633-a4pu6rlu	388	29	,	,	,
cord-353633-a4pu6rlu	388	30	transferrin	transferrin	NN
cord-353633-a4pu6rlu	388	31	,	,	,
cord-353633-a4pu6rlu	388	32	IgG2	igg2	NN
cord-353633-a4pu6rlu	388	33	,	,	,
cord-353633-a4pu6rlu	388	34	IgA1	iga1	UH
cord-353633-a4pu6rlu	388	35	,	,	,
cord-353633-a4pu6rlu	388	36	alpha-1	alpha-1	NN
cord-353633-a4pu6rlu	388	37	antitrypsin	antitrypsin	NN
cord-353633-a4pu6rlu	388	38	,	,	,
cord-353633-a4pu6rlu	388	39	ceruloplasmin	ceruloplasmin	NNP
cord-353633-a4pu6rlu	388	40	)	)	-RRB-
cord-353633-a4pu6rlu	388	41	.	.	.
cord-353633-a4pu6rlu	389	1	The	the	DT
cord-353633-a4pu6rlu	389	2	findings	finding	NNS
cord-353633-a4pu6rlu	389	3	of	of	IN
cord-353633-a4pu6rlu	389	4	these	these	DT
cord-353633-a4pu6rlu	389	5	studies	study	NNS
cord-353633-a4pu6rlu	389	6	suggest	suggest	VBP
cord-353633-a4pu6rlu	389	7	that	that	IN
cord-353633-a4pu6rlu	389	8	in	in	IN
cord-353633-a4pu6rlu	389	9	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	389	10	and	and	CC
cord-353633-a4pu6rlu	389	11	during	during	IN
cord-353633-a4pu6rlu	389	12	its	-PRON-	PRP$
cord-353633-a4pu6rlu	389	13	progression	progression	NN
cord-353633-a4pu6rlu	389	14	from	from	IN
cord-353633-a4pu6rlu	389	15	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	389	16	to	to	IN
cord-353633-a4pu6rlu	389	17	NASH	NASH	NNP
cord-353633-a4pu6rlu	389	18	and	and	CC
cord-353633-a4pu6rlu	389	19	liver	liver	NN
cord-353633-a4pu6rlu	389	20	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	389	21	higher	high	JJR
cord-353633-a4pu6rlu	389	22	concentrations	concentration	NNS
cord-353633-a4pu6rlu	389	23	in	in	IN
cord-353633-a4pu6rlu	389	24	fucosylated	fucosylated	NNP
cord-353633-a4pu6rlu	389	25	,	,	,
cord-353633-a4pu6rlu	389	26	sialylated	sialylated	JJ
cord-353633-a4pu6rlu	389	27	and	and	CC
cord-353633-a4pu6rlu	389	28	agalactosylated	agalactosylate	VBN
cord-353633-a4pu6rlu	389	29	glycans	glycan	NNS
cord-353633-a4pu6rlu	389	30	are	be	VBP
cord-353633-a4pu6rlu	389	31	observed	observe	VBN
cord-353633-a4pu6rlu	389	32	.	.	.
cord-353633-a4pu6rlu	390	1	Sialic	Sialic	NNP
cord-353633-a4pu6rlu	390	2	acids	acid	NNS
cord-353633-a4pu6rlu	390	3	in	in	IN
cord-353633-a4pu6rlu	390	4	glycolipids	glycolipid	NNS
cord-353633-a4pu6rlu	390	5	or	or	CC
cord-353633-a4pu6rlu	390	6	glycoproteins	glycoprotein	NNS
cord-353633-a4pu6rlu	390	7	have	have	VBP
cord-353633-a4pu6rlu	390	8	diverse	diverse	JJ
cord-353633-a4pu6rlu	390	9	functions	function	NNS
cord-353633-a4pu6rlu	390	10	,	,	,
cord-353633-a4pu6rlu	390	11	including	include	VBG
cord-353633-a4pu6rlu	390	12	formation	formation	NN
cord-353633-a4pu6rlu	390	13	of	of	IN
cord-353633-a4pu6rlu	390	14	a	a	DT
cord-353633-a4pu6rlu	390	15	protective	protective	JJ
cord-353633-a4pu6rlu	390	16	cell	cell	NN
cord-353633-a4pu6rlu	390	17	surface	surface	NN
cord-353633-a4pu6rlu	390	18	barrier	barrier	NN
cord-353633-a4pu6rlu	390	19	,	,	,
cord-353633-a4pu6rlu	390	20	involvement	involvement	NN
cord-353633-a4pu6rlu	390	21	in	in	IN
cord-353633-a4pu6rlu	390	22	interactions	interaction	NNS
cord-353633-a4pu6rlu	390	23	of	of	IN
cord-353633-a4pu6rlu	390	24	white	white	JJ
cord-353633-a4pu6rlu	390	25	blood	blood	NN
cord-353633-a4pu6rlu	390	26	cells	cell	NNS
cord-353633-a4pu6rlu	390	27	with	with	IN
cord-353633-a4pu6rlu	390	28	endothelial	endothelial	JJ
cord-353633-a4pu6rlu	390	29	lining	lining	NN
cord-353633-a4pu6rlu	390	30	of	of	IN
cord-353633-a4pu6rlu	390	31	blood	blood	NN
cord-353633-a4pu6rlu	390	32	vessels	vessel	NNS
cord-353633-a4pu6rlu	390	33	,	,	,
cord-353633-a4pu6rlu	390	34	recognition	recognition	NN
cord-353633-a4pu6rlu	390	35	by	by	IN
cord-353633-a4pu6rlu	390	36	pathogens	pathogen	NNS
cord-353633-a4pu6rlu	390	37	and	and	CC
cord-353633-a4pu6rlu	390	38	toxins	toxin	NNS
cord-353633-a4pu6rlu	390	39	and	and	CC
cord-353633-a4pu6rlu	390	40	facilitation	facilitation	NN
cord-353633-a4pu6rlu	390	41	of	of	IN
cord-353633-a4pu6rlu	390	42	cell	cell	NN
cord-353633-a4pu6rlu	390	43	migration	migration	NN
cord-353633-a4pu6rlu	390	44	by	by	IN
cord-353633-a4pu6rlu	390	45	some	some	DT
cord-353633-a4pu6rlu	390	46	cancers	cancer	NNS
cord-353633-a4pu6rlu	390	47	[	[	-LRB-
cord-353633-a4pu6rlu	390	48	216	216	CD
cord-353633-a4pu6rlu	390	49	]	]	-RRB-
cord-353633-a4pu6rlu	390	50	.	.	.
cord-353633-a4pu6rlu	391	1	Circulating	circulate	VBG
cord-353633-a4pu6rlu	391	2	sialic	sialic	JJ
cord-353633-a4pu6rlu	391	3	acid	acid	NN
cord-353633-a4pu6rlu	391	4	levels	level	NNS
cord-353633-a4pu6rlu	391	5	have	have	VBP
cord-353633-a4pu6rlu	391	6	been	be	VBN
cord-353633-a4pu6rlu	391	7	positively	positively	RB
cord-353633-a4pu6rlu	391	8	associated	associate	VBN
cord-353633-a4pu6rlu	391	9	with	with	IN
cord-353633-a4pu6rlu	391	10	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	391	11	syndrome	syndrome	NN
cord-353633-a4pu6rlu	391	12	and	and	CC
cord-353633-a4pu6rlu	391	13	with	with	IN
cord-353633-a4pu6rlu	391	14	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	391	15	[	[	-LRB-
cord-353633-a4pu6rlu	391	16	217	217	CD
cord-353633-a4pu6rlu	391	17	,	,	,
cord-353633-a4pu6rlu	391	18	218	218	CD
cord-353633-a4pu6rlu	391	19	]	]	-RRB-
cord-353633-a4pu6rlu	391	20	.	.	.
cord-353633-a4pu6rlu	392	1	Fucosylated	fucosylate	VBN
cord-353633-a4pu6rlu	392	2	glycans	glycan	NNS
cord-353633-a4pu6rlu	392	3	are	be	VBP
cord-353633-a4pu6rlu	392	4	also	also	RB
cord-353633-a4pu6rlu	392	5	involved	involve	VBN
cord-353633-a4pu6rlu	392	6	in	in	IN
cord-353633-a4pu6rlu	392	7	a	a	DT
cord-353633-a4pu6rlu	392	8	variety	variety	NN
cord-353633-a4pu6rlu	392	9	of	of	IN
cord-353633-a4pu6rlu	392	10	physiological	physiological	JJ
cord-353633-a4pu6rlu	392	11	and	and	CC
cord-353633-a4pu6rlu	392	12	pathological	pathological	JJ
cord-353633-a4pu6rlu	392	13	procedures	procedure	NNS
cord-353633-a4pu6rlu	392	14	,	,	,
cord-353633-a4pu6rlu	392	15	including	include	VBG
cord-353633-a4pu6rlu	392	16	cell	cell	NN
cord-353633-a4pu6rlu	392	17	adhesion	adhesion	NN
cord-353633-a4pu6rlu	392	18	and	and	CC
cord-353633-a4pu6rlu	392	19	migration	migration	NN
cord-353633-a4pu6rlu	392	20	,	,	,
cord-353633-a4pu6rlu	392	21	angiogenesis	angiogenesis	NN
cord-353633-a4pu6rlu	392	22	,	,	,
cord-353633-a4pu6rlu	392	23	malignancy	malignancy	NN
cord-353633-a4pu6rlu	392	24	,	,	,
cord-353633-a4pu6rlu	392	25	tumor	tumor	NN
cord-353633-a4pu6rlu	392	26	metastasis	metastasis	NN
cord-353633-a4pu6rlu	392	27	as	as	RB
cord-353633-a4pu6rlu	392	28	well	well	RB
cord-353633-a4pu6rlu	392	29	as	as	IN
cord-353633-a4pu6rlu	392	30	immune	immune	JJ
cord-353633-a4pu6rlu	392	31	cell	cell	NN
cord-353633-a4pu6rlu	392	32	development	development	NN
cord-353633-a4pu6rlu	392	33	and	and	CC
cord-353633-a4pu6rlu	392	34	regulation	regulation	NN
cord-353633-a4pu6rlu	392	35	[	[	-LRB-
cord-353633-a4pu6rlu	392	36	219	219	CD
cord-353633-a4pu6rlu	392	37	]	]	-RRB-
cord-353633-a4pu6rlu	392	38	.	.	.
cord-353633-a4pu6rlu	393	1	Consequently	consequently	RB
cord-353633-a4pu6rlu	393	2	changes	change	VBZ
cord-353633-a4pu6rlu	393	3	in	in	IN
cord-353633-a4pu6rlu	393	4	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	393	5	have	have	VBP
cord-353633-a4pu6rlu	393	6	been	be	VBN
cord-353633-a4pu6rlu	393	7	reported	report	VBN
cord-353633-a4pu6rlu	393	8	in	in	IN
cord-353633-a4pu6rlu	393	9	numerous	numerous	JJ
cord-353633-a4pu6rlu	393	10	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	393	11	conditions	condition	NNS
cord-353633-a4pu6rlu	393	12	,	,	,
cord-353633-a4pu6rlu	393	13	such	such	JJ
cord-353633-a4pu6rlu	393	14	as	as	IN
cord-353633-a4pu6rlu	393	15	in	in	IN
cord-353633-a4pu6rlu	393	16	rheumatoid	rheumatoid	NN
cord-353633-a4pu6rlu	393	17	arthritis	arthritis	NN
cord-353633-a4pu6rlu	393	18	,	,	,
cord-353633-a4pu6rlu	393	19	chronic	chronic	JJ
cord-353633-a4pu6rlu	393	20	pancreatitis	pancreatitis	NN
cord-353633-a4pu6rlu	393	21	,	,	,
cord-353633-a4pu6rlu	393	22	sickle	sickle	NN
cord-353633-a4pu6rlu	393	23	cell	cell	NN
cord-353633-a4pu6rlu	393	24	disease	disease	NN
cord-353633-a4pu6rlu	393	25	and	and	CC
cord-353633-a4pu6rlu	393	26	Crohn	Crohn	NNP
cord-353633-a4pu6rlu	393	27	disease	disease	NN
cord-353633-a4pu6rlu	393	28	[	[	-LRB-
cord-353633-a4pu6rlu	393	29	219	219	CD
cord-353633-a4pu6rlu	393	30	]	]	-RRB-
cord-353633-a4pu6rlu	393	31	.	.	.
cord-353633-a4pu6rlu	394	1	In	in	IN
cord-353633-a4pu6rlu	394	2	the	the	DT
cord-353633-a4pu6rlu	394	3	liver	liver	NN
cord-353633-a4pu6rlu	394	4	,	,	,
cord-353633-a4pu6rlu	394	5	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	394	6	serves	serve	VBZ
cord-353633-a4pu6rlu	394	7	as	as	IN
cord-353633-a4pu6rlu	394	8	a	a	DT
cord-353633-a4pu6rlu	394	9	signal	signal	NN
cord-353633-a4pu6rlu	394	10	for	for	IN
cord-353633-a4pu6rlu	394	11	the	the	DT
cord-353633-a4pu6rlu	394	12	secretion	secretion	NN
cord-353633-a4pu6rlu	394	13	of	of	IN
cord-353633-a4pu6rlu	394	14	fucosylated	fucosylate	VBN
cord-353633-a4pu6rlu	394	15	glycoproteins	glycoprotein	NNS
cord-353633-a4pu6rlu	394	16	from	from	IN
cord-353633-a4pu6rlu	394	17	normal	normal	JJ
cord-353633-a4pu6rlu	394	18	J	J	NNP
cord-353633-a4pu6rlu	394	19	o	o	NN
cord-353633-a4pu6rlu	394	20	u	u	NN
cord-353633-a4pu6rlu	394	21	r	r	NN
cord-353633-a4pu6rlu	394	22	n	n	NN
cord-353633-a4pu6rlu	394	23	a	a	DT
cord-353633-a4pu6rlu	394	24	l	l	NN
cord-353633-a4pu6rlu	394	25	P	p	NN
cord-353633-a4pu6rlu	394	26	r	r	NN
cord-353633-a4pu6rlu	394	27	e	e	NN
cord-353633-a4pu6rlu	394	28	-p	-p	NN
cord-353633-a4pu6rlu	395	1	r	r	NN
cord-353633-a4pu6rlu	395	2	o	o	NN
cord-353633-a4pu6rlu	395	3	o	o	NN
cord-353633-a4pu6rlu	395	4	f	f	NN
cord-353633-a4pu6rlu	395	5	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	395	6	into	into	IN
cord-353633-a4pu6rlu	395	7	bile	bile	NN
cord-353633-a4pu6rlu	395	8	[	[	-LRB-
cord-353633-a4pu6rlu	395	9	219	219	CD
cord-353633-a4pu6rlu	395	10	]	]	-RRB-
cord-353633-a4pu6rlu	395	11	.	.	.
cord-353633-a4pu6rlu	396	1	In	in	IN
cord-353633-a4pu6rlu	396	2	ballooning	ballooning	NN
cord-353633-a4pu6rlu	396	3	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	396	4	,	,	,
cord-353633-a4pu6rlu	396	5	which	which	WDT
cord-353633-a4pu6rlu	396	6	are	be	VBP
cord-353633-a4pu6rlu	396	7	observed	observe	VBN
cord-353633-a4pu6rlu	396	8	in	in	IN
cord-353633-a4pu6rlu	396	9	NASH	NASH	NNP
cord-353633-a4pu6rlu	396	10	,	,	,
cord-353633-a4pu6rlu	396	11	the	the	DT
cord-353633-a4pu6rlu	396	12	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	396	13	-	-	HYPH
cord-353633-a4pu6rlu	396	14	related	relate	VBN
cord-353633-a4pu6rlu	396	15	sorting	sorting	NN
cord-353633-a4pu6rlu	396	16	machinery	machinery	NN
cord-353633-a4pu6rlu	396	17	is	be	VBZ
cord-353633-a4pu6rlu	396	18	dysfunctional	dysfunctional	JJ
cord-353633-a4pu6rlu	396	19	which	which	WDT
cord-353633-a4pu6rlu	396	20	may	may	MD
cord-353633-a4pu6rlu	396	21	result	result	VB
cord-353633-a4pu6rlu	396	22	in	in	IN
cord-353633-a4pu6rlu	396	23	the	the	DT
cord-353633-a4pu6rlu	396	24	secretion	secretion	NN
cord-353633-a4pu6rlu	396	25	of	of	IN
cord-353633-a4pu6rlu	396	26	the	the	DT
cord-353633-a4pu6rlu	396	27	fucosylated	fucosylate	VBN
cord-353633-a4pu6rlu	396	28	glycoproteins	glycoprotein	NNS
cord-353633-a4pu6rlu	396	29	in	in	IN
cord-353633-a4pu6rlu	396	30	the	the	DT
cord-353633-a4pu6rlu	396	31	sera	sera	NNP
cord-353633-a4pu6rlu	396	32	instead	instead	RB
cord-353633-a4pu6rlu	396	33	of	of	IN
cord-353633-a4pu6rlu	396	34	bile	bile	NN
cord-353633-a4pu6rlu	396	35	[	[	-LRB-
cord-353633-a4pu6rlu	396	36	219	219	CD
cord-353633-a4pu6rlu	396	37	]	]	-RRB-
cord-353633-a4pu6rlu	396	38	.	.	.
cord-353633-a4pu6rlu	397	1	Similarly	similarly	RB
cord-353633-a4pu6rlu	397	2	,	,	,
cord-353633-a4pu6rlu	397	3	hypogalactosylation	hypogalactosylation	NN
cord-353633-a4pu6rlu	397	4	(	(	-LRB-
cord-353633-a4pu6rlu	397	5	lack	lack	NN
cord-353633-a4pu6rlu	397	6	of	of	IN
cord-353633-a4pu6rlu	397	7	galactose	galactose	NN
cord-353633-a4pu6rlu	397	8	in	in	IN
cord-353633-a4pu6rlu	397	9	the	the	DT
cord-353633-a4pu6rlu	397	10	formed	form	VBN
cord-353633-a4pu6rlu	397	11	glycoprotein	glycoprotein	NN
cord-353633-a4pu6rlu	397	12	or	or	CC
cord-353633-a4pu6rlu	397	13	glycolipid	glycolipid	NNP
cord-353633-a4pu6rlu	397	14	)	)	-RRB-
cord-353633-a4pu6rlu	397	15	especially	especially	RB
cord-353633-a4pu6rlu	397	16	of	of	IN
cord-353633-a4pu6rlu	397	17	IgG	IgG	NNP
cord-353633-a4pu6rlu	397	18	has	have	VBZ
cord-353633-a4pu6rlu	397	19	been	be	VBN
cord-353633-a4pu6rlu	397	20	associated	associate	VBN
cord-353633-a4pu6rlu	397	21	with	with	IN
cord-353633-a4pu6rlu	397	22	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	397	23	response	response	NN
cord-353633-a4pu6rlu	397	24	and	and	CC
cord-353633-a4pu6rlu	397	25	with	with	IN
cord-353633-a4pu6rlu	397	26	a	a	DT
cord-353633-a4pu6rlu	397	27	number	number	NN
cord-353633-a4pu6rlu	397	28	of	of	IN
cord-353633-a4pu6rlu	397	29	autoimmune	autoimmune	JJ
cord-353633-a4pu6rlu	397	30	diseases	disease	NNS
cord-353633-a4pu6rlu	397	31	[	[	-LRB-
cord-353633-a4pu6rlu	397	32	213	213	CD
cord-353633-a4pu6rlu	397	33	]	]	-RRB-
cord-353633-a4pu6rlu	397	34	.	.	.
cord-353633-a4pu6rlu	398	1	Most	Most	JJS
cord-353633-a4pu6rlu	398	2	of	of	IN
cord-353633-a4pu6rlu	398	3	the	the	DT
cord-353633-a4pu6rlu	398	4	glycomic	glycomic	NNP
cord-353633-a4pu6rlu	398	5	studies	study	NNS
cord-353633-a4pu6rlu	398	6	in	in	IN
cord-353633-a4pu6rlu	398	7	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	398	8	have	have	VBP
cord-353633-a4pu6rlu	398	9	tried	try	VBN
cord-353633-a4pu6rlu	398	10	to	to	TO
cord-353633-a4pu6rlu	398	11	identify	identify	VB
cord-353633-a4pu6rlu	398	12	glycans	glycan	NNS
cord-353633-a4pu6rlu	398	13	or	or	CC
cord-353633-a4pu6rlu	398	14	glycoproteins	glycoprotein	NNS
cord-353633-a4pu6rlu	398	15	that	that	WDT
cord-353633-a4pu6rlu	398	16	can	can	MD
cord-353633-a4pu6rlu	398	17	serve	serve	VB
cord-353633-a4pu6rlu	398	18	as	as	IN
cord-353633-a4pu6rlu	398	19	blood	blood	NN
cord-353633-a4pu6rlu	398	20	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	398	21	for	for	IN
cord-353633-a4pu6rlu	398	22	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	398	23	between	between	IN
cord-353633-a4pu6rlu	398	24	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	398	25	and	and	CC
cord-353633-a4pu6rlu	398	26	NASH	NASH	NNP
cord-353633-a4pu6rlu	398	27	or	or	CC
cord-353633-a4pu6rlu	398	28	for	for	IN
cord-353633-a4pu6rlu	398	29	detection	detection	NN
cord-353633-a4pu6rlu	398	30	of	of	IN
cord-353633-a4pu6rlu	398	31	the	the	DT
cord-353633-a4pu6rlu	398	32	presence	presence	NN
cord-353633-a4pu6rlu	398	33	of	of	IN
cord-353633-a4pu6rlu	398	34	liver	liver	NN
cord-353633-a4pu6rlu	398	35	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	398	36	and	and	CC
cord-353633-a4pu6rlu	398	37	its	-PRON-	PRP$
cord-353633-a4pu6rlu	398	38	stage	stage	NN
cord-353633-a4pu6rlu	398	39	(	(	-LRB-
cord-353633-a4pu6rlu	398	40	Table	table	NN
cord-353633-a4pu6rlu	398	41	5	5	CD
cord-353633-a4pu6rlu	398	42	)	)	-RRB-
cord-353633-a4pu6rlu	398	43	.	.	.
cord-353633-a4pu6rlu	399	1	The	the	DT
cord-353633-a4pu6rlu	399	2	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	399	3	accuracy	accuracy	NN
cord-353633-a4pu6rlu	399	4	of	of	IN
cord-353633-a4pu6rlu	399	5	most	most	JJS
cord-353633-a4pu6rlu	399	6	of	of	IN
cord-353633-a4pu6rlu	399	7	these	these	DT
cord-353633-a4pu6rlu	399	8	tests	test	NNS
cord-353633-a4pu6rlu	399	9	has	have	VBZ
cord-353633-a4pu6rlu	399	10	been	be	VBN
cord-353633-a4pu6rlu	399	11	limited	limit	VBN
cord-353633-a4pu6rlu	399	12	,	,	,
cord-353633-a4pu6rlu	399	13	with	with	IN
cord-353633-a4pu6rlu	399	14	some	some	DT
cord-353633-a4pu6rlu	399	15	reporting	report	VBG
cord-353633-a4pu6rlu	399	16	higher	high	JJR
cord-353633-a4pu6rlu	399	17	accuracy	accuracy	NN
cord-353633-a4pu6rlu	399	18	for	for	IN
cord-353633-a4pu6rlu	399	19	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	399	20	NASH	NASH	NNP
cord-353633-a4pu6rlu	399	21	and	and	CC
cord-353633-a4pu6rlu	399	22	others	other	NNS
cord-353633-a4pu6rlu	399	23	for	for	IN
cord-353633-a4pu6rlu	399	24	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	399	25	advanced	advanced	JJ
cord-353633-a4pu6rlu	399	26	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	399	27	.	.	.
cord-353633-a4pu6rlu	400	1	This	this	DT
cord-353633-a4pu6rlu	400	2	suggests	suggest	VBZ
cord-353633-a4pu6rlu	400	3	that	that	IN
cord-353633-a4pu6rlu	400	4	although	although	IN
cord-353633-a4pu6rlu	400	5	changes	change	NNS
cord-353633-a4pu6rlu	400	6	in	in	IN
cord-353633-a4pu6rlu	400	7	circulating	circulate	VBG
cord-353633-a4pu6rlu	400	8	glycome	glycome	NNP
cord-353633-a4pu6rlu	400	9	/	/	SYM
cord-353633-a4pu6rlu	400	10	glycoproteins	glycoprotein	NNS
cord-353633-a4pu6rlu	400	11	are	be	VBP
cord-353633-a4pu6rlu	400	12	observed	observe	VBN
cord-353633-a4pu6rlu	400	13	in	in	IN
cord-353633-a4pu6rlu	400	14	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	400	15	,	,	,
cord-353633-a4pu6rlu	400	16	these	these	DT
cord-353633-a4pu6rlu	400	17	are	be	VBP
cord-353633-a4pu6rlu	400	18	not	not	RB
cord-353633-a4pu6rlu	400	19	sufficient	sufficient	JJ
cord-353633-a4pu6rlu	400	20	in	in	IN
cord-353633-a4pu6rlu	400	21	order	order	NN
cord-353633-a4pu6rlu	400	22	to	to	TO
cord-353633-a4pu6rlu	400	23	be	be	VB
cord-353633-a4pu6rlu	400	24	used	use	VBN
cord-353633-a4pu6rlu	400	25	alone	alone	RB
cord-353633-a4pu6rlu	400	26	for	for	IN
cord-353633-a4pu6rlu	400	27	the	the	DT
cord-353633-a4pu6rlu	400	28	development	development	NN
cord-353633-a4pu6rlu	400	29	of	of	IN
cord-353633-a4pu6rlu	400	30	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	400	31	models	model	NNS
cord-353633-a4pu6rlu	400	32	of	of	IN
cord-353633-a4pu6rlu	400	33	the	the	DT
cord-353633-a4pu6rlu	400	34	disease	disease	NN
cord-353633-a4pu6rlu	400	35	and	and	CC
cord-353633-a4pu6rlu	400	36	thus	thus	RB
cord-353633-a4pu6rlu	400	37	combination	combination	NN
cord-353633-a4pu6rlu	400	38	with	with	IN
cord-353633-a4pu6rlu	400	39	other	other	JJ
cord-353633-a4pu6rlu	400	40	clinical	clinical	JJ
cord-353633-a4pu6rlu	400	41	or	or	CC
cord-353633-a4pu6rlu	400	42	biochemical	biochemical	JJ
cord-353633-a4pu6rlu	400	43	parameters	parameter	NNS
cord-353633-a4pu6rlu	400	44	are	be	VBP
cord-353633-a4pu6rlu	400	45	needed	need	VBN
cord-353633-a4pu6rlu	400	46	.	.	.
cord-353633-a4pu6rlu	401	1	In	in	IN
cord-353633-a4pu6rlu	401	2	this	this	DT
cord-353633-a4pu6rlu	401	3	context	context	NN
cord-353633-a4pu6rlu	401	4	,	,	,
cord-353633-a4pu6rlu	401	5	fucosylated	fucosylate	VBN
cord-353633-a4pu6rlu	401	6	-	-	HYPH
cord-353633-a4pu6rlu	401	7	haptoglobin	haptoglobin	NN
cord-353633-a4pu6rlu	401	8	showed	show	VBD
cord-353633-a4pu6rlu	401	9	below	below	IN
cord-353633-a4pu6rlu	401	10	70	70	CD
cord-353633-a4pu6rlu	401	11	%	%	NN
cord-353633-a4pu6rlu	401	12	accuracy	accuracy	NN
cord-353633-a4pu6rlu	401	13	at	at	IN
cord-353633-a4pu6rlu	401	14	differentiating	differentiate	VBG
cord-353633-a4pu6rlu	401	15	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	401	16	from	from	IN
cord-353633-a4pu6rlu	401	17	NASH	NASH	NNP
cord-353633-a4pu6rlu	401	18	,	,	,
cord-353633-a4pu6rlu	401	19	but	but	CC
cord-353633-a4pu6rlu	401	20	76	76	CD
cord-353633-a4pu6rlu	401	21	-	-	SYM
cord-353633-a4pu6rlu	401	22	81	81	CD
cord-353633-a4pu6rlu	401	23	%	%	NN
cord-353633-a4pu6rlu	401	24	when	when	WRB
cord-353633-a4pu6rlu	401	25	combined	combine	VBN
cord-353633-a4pu6rlu	401	26	with	with	IN
cord-353633-a4pu6rlu	401	27	Mac2bp	mac2bp	NN
cord-353633-a4pu6rlu	401	28	[	[	-LRB-
cord-353633-a4pu6rlu	401	29	220	220	CD
cord-353633-a4pu6rlu	401	30	]	]	-RRB-
cord-353633-a4pu6rlu	401	31	.	.	.
cord-353633-a4pu6rlu	402	1	Similarly	similarly	RB
cord-353633-a4pu6rlu	402	2	,	,	,
cord-353633-a4pu6rlu	402	3	in	in	IN
cord-353633-a4pu6rlu	402	4	our	-PRON-	PRP$
cord-353633-a4pu6rlu	402	5	study	study	NN
cord-353633-a4pu6rlu	402	6	,	,	,
cord-353633-a4pu6rlu	402	7	which	which	WDT
cord-353633-a4pu6rlu	402	8	detected	detect	VBD
cord-353633-a4pu6rlu	402	9	with	with	IN
cord-353633-a4pu6rlu	402	10	the	the	DT
cord-353633-a4pu6rlu	402	11	use	use	NN
cord-353633-a4pu6rlu	402	12	of	of	IN
cord-353633-a4pu6rlu	402	13	mass	mass	JJ
cord-353633-a4pu6rlu	402	14	-	-	HYPH
cord-353633-a4pu6rlu	402	15	spectrometry	spectrometry	NN
cord-353633-a4pu6rlu	402	16	the	the	DT
cord-353633-a4pu6rlu	402	17	highest	high	JJS
cord-353633-a4pu6rlu	402	18	number	number	NN
cord-353633-a4pu6rlu	402	19	of	of	IN
cord-353633-a4pu6rlu	402	20	glycans	glycan	NNS
cord-353633-a4pu6rlu	402	21	so	so	RB
cord-353633-a4pu6rlu	402	22	far	far	RB
cord-353633-a4pu6rlu	402	23	,	,	,
cord-353633-a4pu6rlu	402	24	the	the	DT
cord-353633-a4pu6rlu	402	25	concentrations	concentration	NNS
cord-353633-a4pu6rlu	402	26	of	of	IN
cord-353633-a4pu6rlu	402	27	glycans	glycan	NNS
cord-353633-a4pu6rlu	402	28	in	in	IN
cord-353633-a4pu6rlu	402	29	serum	serum	NN
cord-353633-a4pu6rlu	402	30	were	be	VBD
cord-353633-a4pu6rlu	402	31	able	able	JJ
cord-353633-a4pu6rlu	402	32	to	to	TO
cord-353633-a4pu6rlu	402	33	differentiate	differentiate	VB
cord-353633-a4pu6rlu	402	34	between	between	IN
cord-353633-a4pu6rlu	402	35	the	the	DT
cord-353633-a4pu6rlu	402	36	presence	presence	NN
cord-353633-a4pu6rlu	402	37	of	of	IN
cord-353633-a4pu6rlu	402	38	liver	liver	NN
cord-353633-a4pu6rlu	402	39	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	402	40	or	or	CC
cord-353633-a4pu6rlu	402	41	not	not	RB
cord-353633-a4pu6rlu	402	42	with	with	IN
cord-353633-a4pu6rlu	402	43	76	76	CD
cord-353633-a4pu6rlu	402	44	%	%	NN
cord-353633-a4pu6rlu	402	45	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	402	46	and	and	CC
cord-353633-a4pu6rlu	402	47	74	74	CD
cord-353633-a4pu6rlu	402	48	%	%	NN
cord-353633-a4pu6rlu	402	49	specificity	specificity	NN
cord-353633-a4pu6rlu	402	50	[	[	-LRB-
cord-353633-a4pu6rlu	402	51	144	144	CD
cord-353633-a4pu6rlu	402	52	]	]	-RRB-
cord-353633-a4pu6rlu	402	53	.	.	.
cord-353633-a4pu6rlu	403	1	Glycans	glycan	NNS
cord-353633-a4pu6rlu	403	2	alone	alone	RB
cord-353633-a4pu6rlu	403	3	could	could	MD
cord-353633-a4pu6rlu	403	4	poorly	poorly	RB
cord-353633-a4pu6rlu	403	5	differentiate	differentiate	VB
cord-353633-a4pu6rlu	403	6	between	between	IN
cord-353633-a4pu6rlu	403	7	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	403	8	and	and	CC
cord-353633-a4pu6rlu	403	9	NASH	NASH	NNP
cord-353633-a4pu6rlu	403	10	but	but	CC
cord-353633-a4pu6rlu	403	11	when	when	WRB
cord-353633-a4pu6rlu	403	12	combined	combine	VBN
cord-353633-a4pu6rlu	403	13	with	with	IN
cord-353633-a4pu6rlu	403	14	lipid	lipid	NN
cord-353633-a4pu6rlu	403	15	species	specie	NNS
cord-353633-a4pu6rlu	403	16	in	in	IN
cord-353633-a4pu6rlu	403	17	models	model	NNS
cord-353633-a4pu6rlu	403	18	of	of	IN
cord-353633-a4pu6rlu	403	19	20	20	CD
cord-353633-a4pu6rlu	403	20	variables	variable	NNS
cord-353633-a4pu6rlu	403	21	(	(	-LRB-
cord-353633-a4pu6rlu	403	22	18	18	CD
cord-353633-a4pu6rlu	403	23	lipid	lipid	NN
cord-353633-a4pu6rlu	403	24	species	specie	NNS
cord-353633-a4pu6rlu	403	25	and	and	CC
cord-353633-a4pu6rlu	403	26	2	2	CD
cord-353633-a4pu6rlu	403	27	J	j	NN
cord-353633-a4pu6rlu	403	28	o	o	NN
cord-353633-a4pu6rlu	403	29	u	u	NN
cord-353633-a4pu6rlu	403	30	r	r	NN
cord-353633-a4pu6rlu	403	31	n	n	NN
cord-353633-a4pu6rlu	403	32	a	a	DT
cord-353633-a4pu6rlu	403	33	l	l	NN
cord-353633-a4pu6rlu	403	34	P	p	NN
cord-353633-a4pu6rlu	403	35	r	r	NN
cord-353633-a4pu6rlu	403	36	e	e	NN
cord-353633-a4pu6rlu	404	1	-p	-p	:
cord-353633-a4pu6rlu	405	1	r	r	NN
cord-353633-a4pu6rlu	405	2	o	o	NN
cord-353633-a4pu6rlu	405	3	o	o	NN
cord-353633-a4pu6rlu	405	4	f	f	NN
cord-353633-a4pu6rlu	405	5	52	52	CD
cord-353633-a4pu6rlu	405	6	glycans	glycan	NNS
cord-353633-a4pu6rlu	405	7	)	)	-RRB-
cord-353633-a4pu6rlu	406	1	the	the	DT
cord-353633-a4pu6rlu	406	2	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	406	3	and	and	CC
cord-353633-a4pu6rlu	406	4	specificity	specificity	NN
cord-353633-a4pu6rlu	406	5	for	for	IN
cord-353633-a4pu6rlu	406	6	discriminating	discriminate	VBG
cord-353633-a4pu6rlu	406	7	between	between	IN
cord-353633-a4pu6rlu	406	8	NASH	NASH	NNP
cord-353633-a4pu6rlu	406	9	,	,	,
cord-353633-a4pu6rlu	406	10	NAFL	NAFL	NNP
cord-353633-a4pu6rlu	406	11	or	or	CC
cord-353633-a4pu6rlu	406	12	healthy	healthy	JJ
cord-353633-a4pu6rlu	406	13	liver	liver	NN
cord-353633-a4pu6rlu	406	14	status	status	NN
cord-353633-a4pu6rlu	406	15	increases	increase	VBZ
cord-353633-a4pu6rlu	406	16	significantly	significantly	RB
cord-353633-a4pu6rlu	406	17	.	.	.
cord-353633-a4pu6rlu	407	1	Regarding	regard	VBG
cord-353633-a4pu6rlu	407	2	potential	potential	JJ
cord-353633-a4pu6rlu	407	3	treatments	treatment	NNS
cord-353633-a4pu6rlu	407	4	,	,	,
cord-353633-a4pu6rlu	407	5	no	no	DT
cord-353633-a4pu6rlu	407	6	study	study	NN
cord-353633-a4pu6rlu	407	7	thus	thus	RB
cord-353633-a4pu6rlu	407	8	far	far	RB
cord-353633-a4pu6rlu	407	9	has	have	VBZ
cord-353633-a4pu6rlu	407	10	investigated	investigate	VBN
cord-353633-a4pu6rlu	407	11	whether	whether	IN
cord-353633-a4pu6rlu	407	12	targeting	target	VBG
cord-353633-a4pu6rlu	407	13	glycome	glycome	NNP
cord-353633-a4pu6rlu	407	14	can	can	MD
cord-353633-a4pu6rlu	407	15	be	be	VB
cord-353633-a4pu6rlu	407	16	a	a	DT
cord-353633-a4pu6rlu	407	17	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	407	18	option	option	NN
cord-353633-a4pu6rlu	407	19	in	in	IN
cord-353633-a4pu6rlu	407	20	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	407	21	.	.	.
cord-353633-a4pu6rlu	408	1	Treatments	treatment	NNS
cord-353633-a4pu6rlu	408	2	aiming	aim	VBG
cord-353633-a4pu6rlu	408	3	to	to	TO
cord-353633-a4pu6rlu	408	4	decrease	decrease	VB
cord-353633-a4pu6rlu	408	5	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	408	6	are	be	VBP
cord-353633-a4pu6rlu	408	7	currently	currently	RB
cord-353633-a4pu6rlu	408	8	under	under	IN
cord-353633-a4pu6rlu	408	9	evaluation	evaluation	NN
cord-353633-a4pu6rlu	408	10	in	in	IN
cord-353633-a4pu6rlu	408	11	autoimmune	autoimmune	JJ
cord-353633-a4pu6rlu	408	12	diseases	disease	NNS
cord-353633-a4pu6rlu	408	13	and	and	CC
cord-353633-a4pu6rlu	408	14	cancer	cancer	NN
cord-353633-a4pu6rlu	408	15	.	.	.
cord-353633-a4pu6rlu	409	1	In	in	IN
cord-353633-a4pu6rlu	409	2	this	this	DT
cord-353633-a4pu6rlu	409	3	context	context	NN
cord-353633-a4pu6rlu	409	4	,	,	,
cord-353633-a4pu6rlu	409	5	inhibition	inhibition	NN
cord-353633-a4pu6rlu	409	6	of	of	IN
cord-353633-a4pu6rlu	409	7	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	409	8	with	with	IN
cord-353633-a4pu6rlu	409	9	a	a	DT
cord-353633-a4pu6rlu	409	10	2-deoxyd	2-deoxyd	CD
cord-353633-a4pu6rlu	409	11	-	-	HYPH
cord-353633-a4pu6rlu	409	12	galactose	galactose	NN
cord-353633-a4pu6rlu	409	13	,	,	,
cord-353633-a4pu6rlu	409	14	a	a	DT
cord-353633-a4pu6rlu	409	15	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	409	16	inhibitor	inhibitor	NN
cord-353633-a4pu6rlu	409	17	,	,	,
cord-353633-a4pu6rlu	409	18	reduces	reduce	VBZ
cord-353633-a4pu6rlu	409	19	inflammation	inflammation	NN
cord-353633-a4pu6rlu	409	20	in	in	IN
cord-353633-a4pu6rlu	409	21	rheumatoid	rheumatoid	NN
cord-353633-a4pu6rlu	409	22	arthritis	arthritis	NN
cord-353633-a4pu6rlu	409	23	by	by	IN
cord-353633-a4pu6rlu	409	24	decreasing	decrease	VBG
cord-353633-a4pu6rlu	409	25	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	409	26	macrophages	macrophage	NNS
cord-353633-a4pu6rlu	409	27	and	and	CC
cord-353633-a4pu6rlu	409	28	Th17	th17	CD
cord-353633-a4pu6rlu	409	29	cells	cell	NNS
cord-353633-a4pu6rlu	409	30	in	in	IN
cord-353633-a4pu6rlu	409	31	the	the	DT
cord-353633-a4pu6rlu	409	32	lymph	lymph	NN
cord-353633-a4pu6rlu	409	33	nodes	node	NNS
cord-353633-a4pu6rlu	409	34	as	as	RB
cord-353633-a4pu6rlu	409	35	well	well	RB
cord-353633-a4pu6rlu	409	36	as	as	IN
cord-353633-a4pu6rlu	409	37	by	by	IN
cord-353633-a4pu6rlu	409	38	reducing	reduce	VBG
cord-353633-a4pu6rlu	409	39	the	the	DT
cord-353633-a4pu6rlu	409	40	levels	level	NNS
cord-353633-a4pu6rlu	409	41	of	of	IN
cord-353633-a4pu6rlu	409	42	TNFα	TNFα	NNS
cord-353633-a4pu6rlu	409	43	,	,	,
cord-353633-a4pu6rlu	409	44	interleukin-6	interleukin-6	NNP
cord-353633-a4pu6rlu	409	45	(	(	-LRB-
cord-353633-a4pu6rlu	409	46	IL-6	IL-6	NNP
cord-353633-a4pu6rlu	409	47	)	)	-RRB-
cord-353633-a4pu6rlu	409	48	,	,	,
cord-353633-a4pu6rlu	409	49	and	and	CC
cord-353633-a4pu6rlu	409	50	antibodies	antibody	NNS
cord-353633-a4pu6rlu	409	51	to	to	TO
cord-353633-a4pu6rlu	409	52	type	type	VB
cord-353633-a4pu6rlu	409	53	II	ii	CD
cord-353633-a4pu6rlu	409	54	collagen	collagen	NN
cord-353633-a4pu6rlu	409	55	in	in	IN
cord-353633-a4pu6rlu	409	56	the	the	DT
cord-353633-a4pu6rlu	409	57	serum	serum	NN
cord-353633-a4pu6rlu	409	58	[	[	-LRB-
cord-353633-a4pu6rlu	409	59	221	221	CD
cord-353633-a4pu6rlu	409	60	]	]	-RRB-
cord-353633-a4pu6rlu	409	61	.	.	.
cord-353633-a4pu6rlu	410	1	Similarly	similarly	RB
cord-353633-a4pu6rlu	410	2	,	,	,
cord-353633-a4pu6rlu	410	3	inhibition	inhibition	NN
cord-353633-a4pu6rlu	410	4	of	of	IN
cord-353633-a4pu6rlu	410	5	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	410	6	by	by	IN
cord-353633-a4pu6rlu	410	7	2-fluorofucose	2-fluorofucose	CD
cord-353633-a4pu6rlu	410	8	suppresses	suppress	VBZ
cord-353633-a4pu6rlu	410	9	the	the	DT
cord-353633-a4pu6rlu	410	10	proliferation	proliferation	NN
cord-353633-a4pu6rlu	410	11	,	,	,
cord-353633-a4pu6rlu	410	12	migration	migration	NN
cord-353633-a4pu6rlu	410	13	and	and	CC
cord-353633-a4pu6rlu	410	14	tumor	tumor	NN
cord-353633-a4pu6rlu	410	15	formation	formation	NN
cord-353633-a4pu6rlu	410	16	of	of	IN
cord-353633-a4pu6rlu	410	17	HepG2	HepG2	NNP
cord-353633-a4pu6rlu	410	18	liver	liver	NN
cord-353633-a4pu6rlu	410	19	cells	cell	NNS
cord-353633-a4pu6rlu	410	20	[	[	-LRB-
cord-353633-a4pu6rlu	410	21	222	222	CD
cord-353633-a4pu6rlu	410	22	]	]	-RRB-
cord-353633-a4pu6rlu	410	23	.	.	.
cord-353633-a4pu6rlu	411	1	Whether	whether	IN
cord-353633-a4pu6rlu	411	2	similar	similar	JJ
cord-353633-a4pu6rlu	411	3	interventions	intervention	NNS
cord-353633-a4pu6rlu	411	4	can	can	MD
cord-353633-a4pu6rlu	411	5	be	be	VB
cord-353633-a4pu6rlu	411	6	beneficial	beneficial	JJ
cord-353633-a4pu6rlu	411	7	in	in	IN
cord-353633-a4pu6rlu	411	8	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	411	9	by	by	IN
cord-353633-a4pu6rlu	411	10	reducing	reduce	VBG
cord-353633-a4pu6rlu	411	11	inflammation	inflammation	NN
cord-353633-a4pu6rlu	411	12	,	,	,
cord-353633-a4pu6rlu	411	13	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	411	14	or	or	CC
cord-353633-a4pu6rlu	411	15	HCC	HCC	NNP
cord-353633-a4pu6rlu	411	16	formation	formation	NN
cord-353633-a4pu6rlu	411	17	should	should	MD
cord-353633-a4pu6rlu	411	18	be	be	VB
cord-353633-a4pu6rlu	411	19	addressed	address	VBN
cord-353633-a4pu6rlu	411	20	in	in	IN
cord-353633-a4pu6rlu	411	21	future	future	JJ
cord-353633-a4pu6rlu	411	22	studies	study	NNS
cord-353633-a4pu6rlu	411	23	.	.	.
cord-353633-a4pu6rlu	412	1	Glycomics	glycomic	NNS
cord-353633-a4pu6rlu	412	2	are	be	VBP
cord-353633-a4pu6rlu	412	3	one	one	CD
cord-353633-a4pu6rlu	412	4	of	of	IN
cord-353633-a4pu6rlu	412	5	the	the	DT
cord-353633-a4pu6rlu	412	6	least	least	JJS
cord-353633-a4pu6rlu	412	7	investigated	investigated	JJ
cord-353633-a4pu6rlu	412	8	"	"	``
cord-353633-a4pu6rlu	412	9	omics	omic	NNS
cord-353633-a4pu6rlu	412	10	"	"	''
cord-353633-a4pu6rlu	412	11	in	in	IN
cord-353633-a4pu6rlu	412	12	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	412	13	.	.	.
cord-353633-a4pu6rlu	413	1	Given	give	VBN
cord-353633-a4pu6rlu	413	2	the	the	DT
cord-353633-a4pu6rlu	413	3	strong	strong	JJ
cord-353633-a4pu6rlu	413	4	relation	relation	NN
cord-353633-a4pu6rlu	413	5	between	between	IN
cord-353633-a4pu6rlu	413	6	glycoprotein	glycoprotein	NN
cord-353633-a4pu6rlu	413	7	-	-	HYPH
cord-353633-a4pu6rlu	413	8	glycolipid	glycolipid	NN
cord-353633-a4pu6rlu	413	9	formation	formation	NN
cord-353633-a4pu6rlu	413	10	and	and	CC
cord-353633-a4pu6rlu	413	11	liver	liver	NN
cord-353633-a4pu6rlu	413	12	function	function	NN
cord-353633-a4pu6rlu	413	13	,	,	,
cord-353633-a4pu6rlu	413	14	more	more	JJR
cord-353633-a4pu6rlu	413	15	studies	study	NNS
cord-353633-a4pu6rlu	413	16	assessing	assess	VBG
cord-353633-a4pu6rlu	413	17	the	the	DT
cord-353633-a4pu6rlu	413	18	potentials	potential	NNS
cord-353633-a4pu6rlu	413	19	of	of	IN
cord-353633-a4pu6rlu	413	20	glycans	glycan	NNS
cord-353633-a4pu6rlu	413	21	in	in	IN
cord-353633-a4pu6rlu	413	22	biomarker	biomarker	NN
cord-353633-a4pu6rlu	413	23	discovery	discovery	NN
cord-353633-a4pu6rlu	413	24	and	and	CC
cord-353633-a4pu6rlu	413	25	drug	drug	NN
cord-353633-a4pu6rlu	413	26	development	development	NN
cord-353633-a4pu6rlu	413	27	are	be	VBP
cord-353633-a4pu6rlu	413	28	needed	need	VBN
cord-353633-a4pu6rlu	413	29	.	.	.
cord-353633-a4pu6rlu	414	1	performed	perform	VBN
cord-353633-a4pu6rlu	414	2	.	.	.
cord-353633-a4pu6rlu	415	1	Thus	thus	RB
cord-353633-a4pu6rlu	415	2	,	,	,
cord-353633-a4pu6rlu	415	3	these	these	DT
cord-353633-a4pu6rlu	415	4	models	model	NNS
cord-353633-a4pu6rlu	415	5	often	often	RB
cord-353633-a4pu6rlu	415	6	do	do	VBP
cord-353633-a4pu6rlu	415	7	not	not	RB
cord-353633-a4pu6rlu	415	8	account	account	VB
cord-353633-a4pu6rlu	415	9	for	for	IN
cord-353633-a4pu6rlu	415	10	population	population	NN
cord-353633-a4pu6rlu	415	11	heterogeneity	heterogeneity	NN
cord-353633-a4pu6rlu	415	12	,	,	,
cord-353633-a4pu6rlu	415	13	which	which	WDT
cord-353633-a4pu6rlu	415	14	is	be	VBZ
cord-353633-a4pu6rlu	415	15	crucial	crucial	JJ
cord-353633-a4pu6rlu	415	16	for	for	IN
cord-353633-a4pu6rlu	415	17	the	the	DT
cord-353633-a4pu6rlu	415	18	accuracy	accuracy	NN
cord-353633-a4pu6rlu	415	19	all	all	DT
cord-353633-a4pu6rlu	415	20	non	non	JJ
cord-353633-a4pu6rlu	415	21	-	-	JJ
cord-353633-a4pu6rlu	415	22	invasive	invasive	JJ
cord-353633-a4pu6rlu	415	23	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	415	24	panels	panel	NNS
cord-353633-a4pu6rlu	415	25	.	.	.
cord-353633-a4pu6rlu	416	1	This	this	DT
cord-353633-a4pu6rlu	416	2	has	have	VBZ
cord-353633-a4pu6rlu	416	3	been	be	VBN
cord-353633-a4pu6rlu	416	4	repeatedly	repeatedly	RB
cord-353633-a4pu6rlu	416	5	shown	show	VBN
cord-353633-a4pu6rlu	416	6	in	in	IN
cord-353633-a4pu6rlu	416	7	studies	study	NNS
cord-353633-a4pu6rlu	416	8	that	that	WDT
cord-353633-a4pu6rlu	416	9	focused	focus	VBD
cord-353633-a4pu6rlu	416	10	on	on	IN
cord-353633-a4pu6rlu	416	11	patients	patient	NNS
cord-353633-a4pu6rlu	416	12	with	with	IN
cord-353633-a4pu6rlu	416	13	overweight	overweight	JJ
cord-353633-a4pu6rlu	416	14	,	,	,
cord-353633-a4pu6rlu	416	15	obesity	obesity	NN
cord-353633-a4pu6rlu	416	16	and	and	CC
cord-353633-a4pu6rlu	416	17	especially	especially	RB
cord-353633-a4pu6rlu	416	18	with	with	IN
cord-353633-a4pu6rlu	416	19	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	416	20	.	.	.
cord-353633-a4pu6rlu	417	1	Several	several	JJ
cord-353633-a4pu6rlu	417	2	and	and	CC
cord-353633-a4pu6rlu	417	3	diverse	diverse	JJ
cord-353633-a4pu6rlu	417	4	biomarker	biomarker	NN
cord-353633-a4pu6rlu	417	5	panels	panel	NNS
cord-353633-a4pu6rlu	417	6	(	(	-LRB-
cord-353633-a4pu6rlu	417	7	including	include	VBG
cord-353633-a4pu6rlu	417	8	SteatoTest	SteatoTest	NNP
cord-353633-a4pu6rlu	417	9	,	,	,
cord-353633-a4pu6rlu	417	10	ActiTest	ActiTest	NNP
cord-353633-a4pu6rlu	417	11	,	,	,
cord-353633-a4pu6rlu	417	12	NashTest-2	NashTest-2	NNP
cord-353633-a4pu6rlu	417	13	,	,	,
cord-353633-a4pu6rlu	417	14	cytokeratin-18	cytokeratin-18	NNP
cord-353633-a4pu6rlu	417	15	,	,	,
cord-353633-a4pu6rlu	417	16	FibroTest	FibroTest	NNP
cord-353633-a4pu6rlu	417	17	,	,	,
cord-353633-a4pu6rlu	417	18	OWLiver	OWLiver	NNP
cord-353633-a4pu6rlu	417	19	tests	test	NNS
cord-353633-a4pu6rlu	417	20	)	)	-RRB-
cord-353633-a4pu6rlu	417	21	were	be	VBD
cord-353633-a4pu6rlu	417	22	evaluated	evaluate	VBN
cord-353633-a4pu6rlu	417	23	but	but	CC
cord-353633-a4pu6rlu	417	24	none	none	NN
cord-353633-a4pu6rlu	417	25	of	of	IN
cord-353633-a4pu6rlu	417	26	them	-PRON-	PRP
cord-353633-a4pu6rlu	417	27	demonstrated	demonstrate	VBD
cord-353633-a4pu6rlu	417	28	optimal	optimal	JJ
cord-353633-a4pu6rlu	417	29	performance	performance	NN
cord-353633-a4pu6rlu	417	30	for	for	IN
cord-353633-a4pu6rlu	417	31	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	417	32	NASH	NASH	NNP
cord-353633-a4pu6rlu	417	33	or	or	CC
cord-353633-a4pu6rlu	417	34	liver	liver	NN
cord-353633-a4pu6rlu	417	35	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	417	36	especially	especially	RB
cord-353633-a4pu6rlu	417	37	in	in	IN
cord-353633-a4pu6rlu	417	38	patients	patient	NNS
cord-353633-a4pu6rlu	417	39	with	with	IN
cord-353633-a4pu6rlu	417	40	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	417	41	[	[	-LRB-
cord-353633-a4pu6rlu	417	42	5	5	CD
cord-353633-a4pu6rlu	417	43	,	,	,
cord-353633-a4pu6rlu	417	44	13	13	CD
cord-353633-a4pu6rlu	417	45	,	,	,
cord-353633-a4pu6rlu	417	46	181	181	CD
cord-353633-a4pu6rlu	417	47	,	,	,
cord-353633-a4pu6rlu	417	48	223	223	CD
cord-353633-a4pu6rlu	417	49	,	,	,
cord-353633-a4pu6rlu	417	50	224	224	CD
cord-353633-a4pu6rlu	417	51	]	]	-RRB-
cord-353633-a4pu6rlu	417	52	.	.	.
cord-353633-a4pu6rlu	418	1	Third	third	RB
cord-353633-a4pu6rlu	418	2	,	,	,
cord-353633-a4pu6rlu	418	3	very	very	RB
cord-353633-a4pu6rlu	418	4	few	few	JJ
cord-353633-a4pu6rlu	418	5	tests	test	NNS
cord-353633-a4pu6rlu	418	6	have	have	VBP
cord-353633-a4pu6rlu	418	7	been	be	VBN
cord-353633-a4pu6rlu	418	8	evaluated	evaluate	VBN
cord-353633-a4pu6rlu	418	9	prospectively	prospectively	RB
cord-353633-a4pu6rlu	418	10	.	.	.
cord-353633-a4pu6rlu	419	1	This	this	DT
cord-353633-a4pu6rlu	419	2	is	be	VBZ
cord-353633-a4pu6rlu	419	3	a	a	DT
cord-353633-a4pu6rlu	419	4	very	very	RB
cord-353633-a4pu6rlu	419	5	important	important	JJ
cord-353633-a4pu6rlu	419	6	step	step	NN
cord-353633-a4pu6rlu	419	7	,	,	,
cord-353633-a4pu6rlu	419	8	which	which	WDT
cord-353633-a4pu6rlu	419	9	even	even	RB
cord-353633-a4pu6rlu	419	10	other	other	JJ
cord-353633-a4pu6rlu	419	11	simpler	simple	JJR
cord-353633-a4pu6rlu	419	12	algorithms	algorithm	NNS
cord-353633-a4pu6rlu	419	13	or	or	CC
cord-353633-a4pu6rlu	419	14	imaging	imaging	NN
cord-353633-a4pu6rlu	419	15	modalities	modality	NNS
cord-353633-a4pu6rlu	419	16	have	have	VBP
cord-353633-a4pu6rlu	419	17	failed	fail	VBN
cord-353633-a4pu6rlu	419	18	to	to	TO
cord-353633-a4pu6rlu	419	19	pass	pass	VB
cord-353633-a4pu6rlu	419	20	[	[	-LRB-
cord-353633-a4pu6rlu	419	21	225	225	CD
cord-353633-a4pu6rlu	419	22	]	]	-RRB-
cord-353633-a4pu6rlu	419	23	.	.	.
cord-353633-a4pu6rlu	420	1	Additionally	additionally	RB
cord-353633-a4pu6rlu	420	2	,	,	,
cord-353633-a4pu6rlu	420	3	depending	depend	VBG
cord-353633-a4pu6rlu	420	4	on	on	IN
cord-353633-a4pu6rlu	420	5	their	-PRON-	PRP$
cord-353633-a4pu6rlu	420	6	mechanism	mechanism	NN
cord-353633-a4pu6rlu	420	7	of	of	IN
cord-353633-a4pu6rlu	420	8	function	function	NN
cord-353633-a4pu6rlu	420	9	,	,	,
cord-353633-a4pu6rlu	420	10	medications	medication	NNS
cord-353633-a4pu6rlu	420	11	may	may	MD
cord-353633-a4pu6rlu	420	12	have	have	VB
cord-353633-a4pu6rlu	420	13	different	different	JJ
cord-353633-a4pu6rlu	420	14	levels	level	NNS
cord-353633-a4pu6rlu	420	15	of	of	IN
cord-353633-a4pu6rlu	420	16	impact	impact	NN
cord-353633-a4pu6rlu	420	17	on	on	IN
cord-353633-a4pu6rlu	420	18	the	the	DT
cord-353633-a4pu6rlu	420	19	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	420	20	and	and	CC
cord-353633-a4pu6rlu	420	21	lipid	lipid	NN
cord-353633-a4pu6rlu	420	22	profile	profile	NN
cord-353633-a4pu6rlu	420	23	in	in	IN
cord-353633-a4pu6rlu	420	24	the	the	DT
cord-353633-a4pu6rlu	420	25	liver	liver	NN
cord-353633-a4pu6rlu	420	26	which	which	WDT
cord-353633-a4pu6rlu	420	27	may	may	MD
cord-353633-a4pu6rlu	420	28	affect	affect	VB
cord-353633-a4pu6rlu	420	29	circulating	circulate	VBG
cord-353633-a4pu6rlu	420	30	metabolome	metabolome	NNP
cord-353633-a4pu6rlu	420	31	/	/	SYM
cord-353633-a4pu6rlu	420	32	lipidome	lipidome	NNP
cord-353633-a4pu6rlu	420	33	and	and	CC
cord-353633-a4pu6rlu	420	34	its	-PRON-	PRP$
cord-353633-a4pu6rlu	420	35	ability	ability	NN
cord-353633-a4pu6rlu	420	36	to	to	TO
cord-353633-a4pu6rlu	420	37	reflect	reflect	VB
cord-353633-a4pu6rlu	420	38	the	the	DT
cord-353633-a4pu6rlu	420	39	stage	stage	NN
cord-353633-a4pu6rlu	420	40	of	of	IN
cord-353633-a4pu6rlu	420	41	the	the	DT
cord-353633-a4pu6rlu	420	42	disease	disease	NN
cord-353633-a4pu6rlu	420	43	through	through	IN
cord-353633-a4pu6rlu	420	44	a	a	DT
cord-353633-a4pu6rlu	420	45	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	420	46	algorithm	algorithm	NN
cord-353633-a4pu6rlu	420	47	originally	originally	RB
cord-353633-a4pu6rlu	420	48	designed	design	VBN
cord-353633-a4pu6rlu	420	49	in	in	IN
cord-353633-a4pu6rlu	420	50	untreated	untreated	JJ
cord-353633-a4pu6rlu	420	51	patients	patient	NNS
cord-353633-a4pu6rlu	420	52	.	.	.
cord-353633-a4pu6rlu	421	1	Altogether	altogether	RB
cord-353633-a4pu6rlu	421	2	,	,	,
cord-353633-a4pu6rlu	421	3	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	421	4	models	model	NNS
cord-353633-a4pu6rlu	421	5	based	base	VBN
cord-353633-a4pu6rlu	421	6	on	on	IN
cord-353633-a4pu6rlu	421	7	omics	omic	NNS
cord-353633-a4pu6rlu	421	8	have	have	VBP
cord-353633-a4pu6rlu	421	9	yet	yet	RB
cord-353633-a4pu6rlu	421	10	to	to	TO
cord-353633-a4pu6rlu	421	11	reach	reach	VB
cord-353633-a4pu6rlu	421	12	exceptional	exceptional	JJ
cord-353633-a4pu6rlu	421	13	levels	level	NNS
cord-353633-a4pu6rlu	421	14	of	of	IN
cord-353633-a4pu6rlu	421	15	performance	performance	NN
cord-353633-a4pu6rlu	421	16	,	,	,
cord-353633-a4pu6rlu	421	17	while	while	IN
cord-353633-a4pu6rlu	421	18	satisfactory	satisfactory	JJ
cord-353633-a4pu6rlu	421	19	study	study	NN
cord-353633-a4pu6rlu	421	20	outcomes	outcome	NNS
cord-353633-a4pu6rlu	421	21	need	need	VBP
cord-353633-a4pu6rlu	421	22	to	to	TO
cord-353633-a4pu6rlu	421	23	be	be	VB
cord-353633-a4pu6rlu	421	24	cautiously	cautiously	RB
cord-353633-a4pu6rlu	421	25	scrutinized	scrutinize	VBN
cord-353633-a4pu6rlu	421	26	and	and	CC
cord-353633-a4pu6rlu	421	27	repeatedly	repeatedly	RB
cord-353633-a4pu6rlu	421	28	validated	validate	VBD
cord-353633-a4pu6rlu	421	29	into	into	IN
cord-353633-a4pu6rlu	421	30	large	large	JJ
cord-353633-a4pu6rlu	421	31	and	and	CC
cord-353633-a4pu6rlu	421	32	diverse	diverse	JJ
cord-353633-a4pu6rlu	421	33	patient	patient	JJ
cord-353633-a4pu6rlu	421	34	cohorts	cohort	NNS
cord-353633-a4pu6rlu	421	35	both	both	DT
cord-353633-a4pu6rlu	421	36	cross	cross	VBP
cord-353633-a4pu6rlu	421	37	-	-	VBZ
cord-353633-a4pu6rlu	421	38	sectionally	sectionally	RB
cord-353633-a4pu6rlu	421	39	as	as	RB
cord-353633-a4pu6rlu	421	40	well	well	RB
cord-353633-a4pu6rlu	421	41	as	as	IN
cord-353633-a4pu6rlu	421	42	prospectively	prospectively	RB
cord-353633-a4pu6rlu	421	43	.	.	.
cord-353633-a4pu6rlu	422	1	To	to	IN
cord-353633-a4pu6rlu	422	2	this	this	DT
cord-353633-a4pu6rlu	422	3	direction	direction	NN
cord-353633-a4pu6rlu	422	4	,	,	,
cord-353633-a4pu6rlu	422	5	FDA	FDA	NNP
cord-353633-a4pu6rlu	422	6	has	have	VBZ
cord-353633-a4pu6rlu	422	7	recently	recently	RB
cord-353633-a4pu6rlu	422	8	approved	approve	VBN
cord-353633-a4pu6rlu	422	9	the	the	DT
cord-353633-a4pu6rlu	422	10	parallel	parallel	JJ
cord-353633-a4pu6rlu	422	11	evaluation	evaluation	NN
cord-353633-a4pu6rlu	422	12	of	of	IN
cord-353633-a4pu6rlu	422	13	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	422	14	biomarker	biomarker	NN
cord-353633-a4pu6rlu	422	15	panels	panel	NNS
cord-353633-a4pu6rlu	422	16	[	[	-LRB-
cord-353633-a4pu6rlu	422	17	239	239	CD
cord-353633-a4pu6rlu	422	18	]	]	-RRB-
cord-353633-a4pu6rlu	423	1	Metab	Metab	NNP
cord-353633-a4pu6rlu	423	2	J	J	NNP
cord-353633-a4pu6rlu	423	3	o	o	NN
cord-353633-a4pu6rlu	423	4	u	u	NN
cord-353633-a4pu6rlu	423	5	r	r	NN
cord-353633-a4pu6rlu	423	6	n	n	NN
cord-353633-a4pu6rlu	423	7	a	a	DT
cord-353633-a4pu6rlu	423	8	l	l	NN
cord-353633-a4pu6rlu	423	9	P	p	NN
cord-353633-a4pu6rlu	423	10	r	r	NN
cord-353633-a4pu6rlu	423	11	e	e	NN
cord-353633-a4pu6rlu	423	12	-p	-p	NN
cord-353633-a4pu6rlu	424	1	r	r	LS
cord-353633-a4pu6rlu	425	1	o	o	UH
cord-353633-a4pu6rlu	425	2	o	o	NN
cord-353633-a4pu6rlu	425	3	f	f	NN
cord-353633-a4pu6rlu	425	4	(	(	-LRB-
cord-353633-a4pu6rlu	425	5	rs738409	rs738409	NNP
cord-353633-a4pu6rlu	425	6	)	)	-RRB-
cord-353633-a4pu6rlu	425	7	impairs	impair	VBZ
cord-353633-a4pu6rlu	425	8	PUFA	PUFA	NNP
cord-353633-a4pu6rlu	425	9	transfer	transfer	NN
cord-353633-a4pu6rlu	425	10	from	from	IN
cord-353633-a4pu6rlu	425	11	DAGs	dag	NNS
cord-353633-a4pu6rlu	425	12	to	to	IN
cord-353633-a4pu6rlu	425	13	PCs	pc	NNS
cord-353633-a4pu6rlu	425	14	,	,	,
cord-353633-a4pu6rlu	425	15	thus	thus	RB
cord-353633-a4pu6rlu	425	16	increasing	increase	VBG
cord-353633-a4pu6rlu	425	17	PUFA	PUFA	NNP
cord-353633-a4pu6rlu	425	18	in	in	IN
cord-353633-a4pu6rlu	425	19	TG	TG	NNP
cord-353633-a4pu6rlu	425	20	and	and	CC
cord-353633-a4pu6rlu	425	21	DAG	DAG	NNP
cord-353633-a4pu6rlu	425	22	.	.	.
cord-353633-a4pu6rlu	426	1	TM6SF2	tm6sf2	JJ
cord-353633-a4pu6rlu	426	2	E167	e167	NN
cord-353633-a4pu6rlu	426	3	K	K	NNP
cord-353633-a4pu6rlu	426	4	(	(	-LRB-
cord-353633-a4pu6rlu	426	5	rs58542926	rs58542926	NNP
cord-353633-a4pu6rlu	426	6	)	)	-RRB-
cord-353633-a4pu6rlu	426	7	impairs	impair	VBZ
cord-353633-a4pu6rlu	426	8	PUFA	PUFA	NNP
cord-353633-a4pu6rlu	426	9	synthesis	synthesis	NN
cord-353633-a4pu6rlu	426	10	,	,	,
cord-353633-a4pu6rlu	426	11	increases	increase	VBZ
cord-353633-a4pu6rlu	426	12	polyunsaturated	polyunsaturated	JJ
cord-353633-a4pu6rlu	426	13	FFAs	ffa	NNS
cord-353633-a4pu6rlu	426	14	and	and	CC
cord-353633-a4pu6rlu	426	15	prevents	prevent	VBZ
cord-353633-a4pu6rlu	426	16	PUFA	PUFA	NNP
cord-353633-a4pu6rlu	426	17	incorporation	incorporation	NN
cord-353633-a4pu6rlu	426	18	into	into	IN
cord-353633-a4pu6rlu	426	19	TGs	tg	NNS
cord-353633-a4pu6rlu	426	20	and	and	CC
cord-353633-a4pu6rlu	426	21	PCs	pc	NNS
cord-353633-a4pu6rlu	426	22	.	.	.
cord-353633-a4pu6rlu	427	1	Both	both	DT
cord-353633-a4pu6rlu	427	2	mechanisms	mechanism	NNS
cord-353633-a4pu6rlu	427	3	lead	lead	VBP
cord-353633-a4pu6rlu	427	4	to	to	IN
cord-353633-a4pu6rlu	427	5	impaired	impair	VBN
cord-353633-a4pu6rlu	427	6	VLDL	vldl	NN
cord-353633-a4pu6rlu	427	7	synthesis	synthesis	NN
cord-353633-a4pu6rlu	427	8	and	and	CC
cord-353633-a4pu6rlu	427	9	lipid	lipid	NN
cord-353633-a4pu6rlu	427	10	droplet	droplet	NN
cord-353633-a4pu6rlu	427	11	hydrolysis	hydrolysis	NN
cord-353633-a4pu6rlu	427	12	.	.	.
cord-353633-a4pu6rlu	428	1	GCKR	GCKR	NNP
cord-353633-a4pu6rlu	429	1	P446L	p446l	JJ
cord-353633-a4pu6rlu	430	1	(	(	-LRB-
cord-353633-a4pu6rlu	430	2	rs780094	rs780094	NNP
cord-353633-a4pu6rlu	430	3	)	)	-RRB-
cord-353633-a4pu6rlu	430	4	incites	incite	VBZ
cord-353633-a4pu6rlu	430	5	glycolysis	glycolysis	NN
cord-353633-a4pu6rlu	430	6	,	,	,
cord-353633-a4pu6rlu	430	7	glycogen	glycogen	NN
cord-353633-a4pu6rlu	430	8	deposition	deposition	NN
cord-353633-a4pu6rlu	430	9	and	and	CC
cord-353633-a4pu6rlu	430	10	de	de	FW
cord-353633-a4pu6rlu	430	11	novo	novo	NNP
cord-353633-a4pu6rlu	430	12	lipogenesis	lipogenesi	NNS
cord-353633-a4pu6rlu	430	13	by	by	IN
cord-353633-a4pu6rlu	430	14	disinhibiting	disinhibite	VBG
cord-353633-a4pu6rlu	430	15	glucokinase	glucokinase	NN
cord-353633-a4pu6rlu	430	16	.	.	.
cord-353633-a4pu6rlu	431	1	Epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	431	2	modifications	modification	NNS
cord-353633-a4pu6rlu	431	3	characteristic	characteristic	JJ
cord-353633-a4pu6rlu	431	4	of	of	IN
cord-353633-a4pu6rlu	431	5	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	431	6	progression	progression	NN
cord-353633-a4pu6rlu	431	7	include	include	VBP
cord-353633-a4pu6rlu	431	8	CpG	CpG	NNP
cord-353633-a4pu6rlu	431	9	site	site	NN
cord-353633-a4pu6rlu	431	10	hypermethylation	hypermethylation	NN
cord-353633-a4pu6rlu	431	11	,	,	,
cord-353633-a4pu6rlu	431	12	thus	thus	RB
cord-353633-a4pu6rlu	431	13	reduced	reduce	VBN
cord-353633-a4pu6rlu	431	14	expression	expression	NN
cord-353633-a4pu6rlu	431	15	,	,	,
cord-353633-a4pu6rlu	431	16	of	of	IN
cord-353633-a4pu6rlu	431	17	genes	gene	NNS
cord-353633-a4pu6rlu	431	18	pertaining	pertain	VBG
cord-353633-a4pu6rlu	431	19	to	to	IN
cord-353633-a4pu6rlu	431	20	lipid	lipid	NN
cord-353633-a4pu6rlu	431	21	and	and	CC
cord-353633-a4pu6rlu	431	22	aminoacid	aminoacid	JJ
cord-353633-a4pu6rlu	431	23	metabolism	metabolism	NN
cord-353633-a4pu6rlu	431	24	and	and	CC
cord-353633-a4pu6rlu	431	25	stellate	stellate	JJ
cord-353633-a4pu6rlu	431	26	cell	cell	NN
cord-353633-a4pu6rlu	431	27	inhibition	inhibition	NN
cord-353633-a4pu6rlu	431	28	.	.	.
cord-353633-a4pu6rlu	432	1	Hypomethylation	Hypomethylation	NNP
cord-353633-a4pu6rlu	432	2	,	,	,
cord-353633-a4pu6rlu	432	3	thus	thus	RB
cord-353633-a4pu6rlu	432	4	increased	increase	VBN
cord-353633-a4pu6rlu	432	5	expression	expression	NN
cord-353633-a4pu6rlu	432	6	,	,	,
cord-353633-a4pu6rlu	432	7	of	of	IN
cord-353633-a4pu6rlu	432	8	genes	gene	NNS
cord-353633-a4pu6rlu	432	9	pertaining	pertain	VBG
cord-353633-a4pu6rlu	432	10	to	to	IN
cord-353633-a4pu6rlu	432	11	tissue	tissue	NN
cord-353633-a4pu6rlu	432	12	repair	repair	NN
cord-353633-a4pu6rlu	432	13	,	,	,
cord-353633-a4pu6rlu	432	14	inflammation	inflammation	NN
cord-353633-a4pu6rlu	432	15	,	,	,
cord-353633-a4pu6rlu	432	16	carcinogenesis	carcinogenesis	NN
cord-353633-a4pu6rlu	432	17	and	and	CC
cord-353633-a4pu6rlu	432	18	fibrogenesis	fibrogenesis	NN
cord-353633-a4pu6rlu	432	19	,	,	,
cord-353633-a4pu6rlu	432	20	increases	increase	VBZ
cord-353633-a4pu6rlu	432	21	insulin	insulin	NN
cord-353633-a4pu6rlu	432	22	resistance	resistance	NN
cord-353633-a4pu6rlu	432	23	and	and	CC
cord-353633-a4pu6rlu	432	24	further	further	RB
cord-353633-a4pu6rlu	432	25	propagates	propagate	VBZ
cord-353633-a4pu6rlu	432	26	the	the	DT
cord-353633-a4pu6rlu	432	27	disease	disease	NN
cord-353633-a4pu6rlu	432	28	.	.	.
cord-353633-a4pu6rlu	433	1	Methylation	methylation	NN
cord-353633-a4pu6rlu	433	2	levels	level	NNS
cord-353633-a4pu6rlu	433	3	of	of	IN
cord-353633-a4pu6rlu	433	4	cytoskeletal	cytoskeletal	JJ
cord-353633-a4pu6rlu	433	5	,	,	,
cord-353633-a4pu6rlu	433	6	transcriptional	transcriptional	JJ
cord-353633-a4pu6rlu	433	7	,	,	,
cord-353633-a4pu6rlu	433	8	proliferation	proliferation	NN
cord-353633-a4pu6rlu	433	9	-	-	HYPH
cord-353633-a4pu6rlu	433	10	related	relate	VBN
cord-353633-a4pu6rlu	433	11	and	and	CC
cord-353633-a4pu6rlu	433	12	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	433	13	genes	gene	NNS
cord-353633-a4pu6rlu	433	14	are	be	VBP
cord-353633-a4pu6rlu	433	15	affected	affect	VBN
cord-353633-a4pu6rlu	433	16	by	by	IN
cord-353633-a4pu6rlu	433	17	age	age	NN
cord-353633-a4pu6rlu	433	18	,	,	,
cord-353633-a4pu6rlu	433	19	fasting	fast	VBG
cord-353633-a4pu6rlu	433	20	glucose	glucose	NN
cord-353633-a4pu6rlu	433	21	levels	level	NNS
cord-353633-a4pu6rlu	433	22	and	and	CC
cord-353633-a4pu6rlu	433	23	body	body	NN
cord-353633-a4pu6rlu	433	24	weight	weight	NN
cord-353633-a4pu6rlu	433	25	.	.	.
cord-353633-a4pu6rlu	434	1	At	at	IN
cord-353633-a4pu6rlu	434	2	the	the	DT
cord-353633-a4pu6rlu	434	3	histone	histone	NN
cord-353633-a4pu6rlu	434	4	level	level	NN
cord-353633-a4pu6rlu	434	5	,	,	,
cord-353633-a4pu6rlu	434	6	depletion	depletion	NN
cord-353633-a4pu6rlu	434	7	of	of	IN
cord-353633-a4pu6rlu	434	8	sirtuins	sirtuin	NNS
cord-353633-a4pu6rlu	434	9	1	1	CD
cord-353633-a4pu6rlu	434	10	and	and	CC
cord-353633-a4pu6rlu	434	11	3	3	CD
cord-353633-a4pu6rlu	434	12	and	and	CC
cord-353633-a4pu6rlu	434	13	HDAC3	HDAC3	NNP
cord-353633-a4pu6rlu	434	14	may	may	MD
cord-353633-a4pu6rlu	434	15	propagate	propagate	VB
cord-353633-a4pu6rlu	434	16	NASH	NASH	NNP
cord-353633-a4pu6rlu	434	17	and	and	CC
cord-353633-a4pu6rlu	434	18	increase	increase	VB
cord-353633-a4pu6rlu	434	19	susceptibility	susceptibility	NN
cord-353633-a4pu6rlu	434	20	to	to	IN
cord-353633-a4pu6rlu	434	21	MetS	mets	NN
cord-353633-a4pu6rlu	434	22	,	,	,
cord-353633-a4pu6rlu	434	23	insulin	insulin	NN
cord-353633-a4pu6rlu	434	24	resistance	resistance	NN
cord-353633-a4pu6rlu	434	25	and	and	CC
cord-353633-a4pu6rlu	434	26	hyperlipidemia	hyperlipidemia	NN
cord-353633-a4pu6rlu	434	27	.	.	.
cord-353633-a4pu6rlu	435	1	On	on	IN
cord-353633-a4pu6rlu	435	2	the	the	DT
cord-353633-a4pu6rlu	435	3	other	other	JJ
cord-353633-a4pu6rlu	435	4	hand	hand	NN
cord-353633-a4pu6rlu	435	5	,	,	,
cord-353633-a4pu6rlu	435	6	the	the	DT
cord-353633-a4pu6rlu	435	7	glucose	glucose	NN
cord-353633-a4pu6rlu	435	8	-	-	HYPH
cord-353633-a4pu6rlu	435	9	activated	activate	VBN
cord-353633-a4pu6rlu	435	10	HAT	hat	NN
cord-353633-a4pu6rlu	435	11	p300	p300	NNP
cord-353633-a4pu6rlu	435	12	activates	activate	VBZ
cord-353633-a4pu6rlu	435	13	ChREBP	ChREBP	NNP
cord-353633-a4pu6rlu	435	14	and	and	CC
cord-353633-a4pu6rlu	435	15	thus	thus	RB
cord-353633-a4pu6rlu	435	16	precipitates	precipitate	VBZ
cord-353633-a4pu6rlu	435	17	stellate	stellate	JJ
cord-353633-a4pu6rlu	435	18	cell	cell	NN
cord-353633-a4pu6rlu	435	19	activation	activation	NN
cord-353633-a4pu6rlu	435	20	,	,	,
cord-353633-a4pu6rlu	435	21	elevates	elevate	VBZ
cord-353633-a4pu6rlu	435	22	lipogenic	lipogenic	NNP
cord-353633-a4pu6rlu	435	23	gene	gene	NN
cord-353633-a4pu6rlu	435	24	expression	expression	NN
cord-353633-a4pu6rlu	435	25	and	and	CC
cord-353633-a4pu6rlu	435	26	expedites	expedite	VBZ
cord-353633-a4pu6rlu	435	27	steatosis	steatosis	NN
cord-353633-a4pu6rlu	435	28	,	,	,
cord-353633-a4pu6rlu	435	29	though	though	IN
cord-353633-a4pu6rlu	435	30	these	these	DT
cord-353633-a4pu6rlu	435	31	effects	effect	NNS
cord-353633-a4pu6rlu	435	32	can	can	MD
cord-353633-a4pu6rlu	435	33	be	be	VB
cord-353633-a4pu6rlu	435	34	attenuated	attenuate	VBN
cord-353633-a4pu6rlu	435	35	by	by	IN
cord-353633-a4pu6rlu	435	36	tannic	tannic	JJ
cord-353633-a4pu6rlu	435	37	acid	acid	NN
cord-353633-a4pu6rlu	435	38	.	.	.
cord-353633-a4pu6rlu	436	1	Finally	finally	RB
cord-353633-a4pu6rlu	436	2	,	,	,
cord-353633-a4pu6rlu	436	3	the	the	DT
cord-353633-a4pu6rlu	436	4	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	436	5	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	436	6	is	be	VBZ
cord-353633-a4pu6rlu	436	7	characterized	characterize	VBN
cord-353633-a4pu6rlu	436	8	by	by	IN
cord-353633-a4pu6rlu	436	9	overexpression	overexpression	NN
cord-353633-a4pu6rlu	436	10	of	of	IN
cord-353633-a4pu6rlu	436	11	lipid	lipid	NN
cord-353633-a4pu6rlu	436	12	metabolism	metabolism	NN
cord-353633-a4pu6rlu	436	13	,	,	,
cord-353633-a4pu6rlu	436	14	cellular	cellular	JJ
cord-353633-a4pu6rlu	436	15	stress	stress	NN
cord-353633-a4pu6rlu	436	16	,	,	,
cord-353633-a4pu6rlu	436	17	division	division	NN
cord-353633-a4pu6rlu	436	18	and	and	CC
cord-353633-a4pu6rlu	436	19	adhesion	adhesion	NN
cord-353633-a4pu6rlu	436	20	,	,	,
cord-353633-a4pu6rlu	436	21	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	436	22	matrix	matrix	NN
cord-353633-a4pu6rlu	436	23	production	production	NN
cord-353633-a4pu6rlu	436	24	and	and	CC
cord-353633-a4pu6rlu	436	25	repair	repair	NN
cord-353633-a4pu6rlu	436	26	,	,	,
cord-353633-a4pu6rlu	436	27	cancer	cancer	NN
cord-353633-a4pu6rlu	436	28	progression	progression	NN
cord-353633-a4pu6rlu	436	29	and	and	CC
cord-353633-a4pu6rlu	436	30	immunomodulatory	immunomodulatory	JJ
cord-353633-a4pu6rlu	436	31	genes	gene	NNS
cord-353633-a4pu6rlu	436	32	,	,	,
cord-353633-a4pu6rlu	436	33	whereas	whereas	IN
cord-353633-a4pu6rlu	436	34	several	several	JJ
cord-353633-a4pu6rlu	436	35	pro	pro	JJ
cord-353633-a4pu6rlu	436	36	-	-	JJ
cord-353633-a4pu6rlu	436	37	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	436	38	and	and	CC
cord-353633-a4pu6rlu	436	39	insulin	insulin	NN
cord-353633-a4pu6rlu	436	40	signaling	signal	VBG
cord-353633-a4pu6rlu	436	41	genes	gene	NNS
cord-353633-a4pu6rlu	436	42	are	be	VBP
cord-353633-a4pu6rlu	436	43	downregulated	downregulate	VBN
cord-353633-a4pu6rlu	436	44	.	.	.
cord-353633-a4pu6rlu	437	1	miRNAs	miRNAs	NNP
cord-353633-a4pu6rlu	437	2	,	,	,
cord-353633-a4pu6rlu	437	3	especially	especially	RB
cord-353633-a4pu6rlu	437	4	miR-122	miR-122	NNP
cord-353633-a4pu6rlu	437	5	,	,	,
cord-353633-a4pu6rlu	437	6	miR-192	miR-192	NNP
cord-353633-a4pu6rlu	437	7	and	and	CC
cord-353633-a4pu6rlu	437	8	miR-34a	miR-34a	NNP
cord-353633-a4pu6rlu	437	9	,	,	,
cord-353633-a4pu6rlu	437	10	are	be	VBP
cord-353633-a4pu6rlu	437	11	linked	link	VBN
cord-353633-a4pu6rlu	437	12	to	to	IN
cord-353633-a4pu6rlu	437	13	steatosis	steatosis	NN
cord-353633-a4pu6rlu	437	14	,	,	,
cord-353633-a4pu6rlu	437	15	cholesterol	cholesterol	NN
cord-353633-a4pu6rlu	437	16	metabolism	metabolism	NN
cord-353633-a4pu6rlu	437	17	,	,	,
cord-353633-a4pu6rlu	437	18	liver	liver	NN
cord-353633-a4pu6rlu	437	19	cancer	cancer	NN
cord-353633-a4pu6rlu	437	20	,	,	,
cord-353633-a4pu6rlu	437	21	atherogenesis	atherogenesis	NN
cord-353633-a4pu6rlu	437	22	and	and	CC
cord-353633-a4pu6rlu	437	23	MetS	MetS	NNP
cord-353633-a4pu6rlu	437	24	,	,	,
cord-353633-a4pu6rlu	437	25	whereas	whereas	IN
cord-353633-a4pu6rlu	437	26	other	other	JJ
cord-353633-a4pu6rlu	437	27	noncoding	noncoding	JJ
cord-353633-a4pu6rlu	437	28	molecules	molecule	NNS
cord-353633-a4pu6rlu	437	29	,	,	,
cord-353633-a4pu6rlu	437	30	such	such	JJ
cord-353633-a4pu6rlu	437	31	as	as	IN
cord-353633-a4pu6rlu	437	32	lncRNAs	lncRNAs	NNP
cord-353633-a4pu6rlu	437	33	,	,	,
cord-353633-a4pu6rlu	437	34	are	be	VBP
cord-353633-a4pu6rlu	437	35	indicators	indicator	NNS
cord-353633-a4pu6rlu	437	36	of	of	IN
cord-353633-a4pu6rlu	437	37	NASH	NASH	NNP
cord-353633-a4pu6rlu	437	38	grade	grade	NN
cord-353633-a4pu6rlu	437	39	and	and	CC
cord-353633-a4pu6rlu	437	40	hepatocellular	hepatocellular	JJ
cord-353633-a4pu6rlu	437	41	viability	viability	NN
cord-353633-a4pu6rlu	437	42	.	.	.
cord-353633-a4pu6rlu	438	1	The	the	DT
cord-353633-a4pu6rlu	438	2	uncontrolled	uncontrolled	JJ
cord-353633-a4pu6rlu	438	3	lipolysis	lipolysis	NN
cord-353633-a4pu6rlu	438	4	from	from	IN
cord-353633-a4pu6rlu	438	5	adipose	adipose	JJ
cord-353633-a4pu6rlu	438	6	tissue	tissue	NN
cord-353633-a4pu6rlu	438	7	,	,	,
cord-353633-a4pu6rlu	438	8	the	the	DT
cord-353633-a4pu6rlu	438	9	increased	increase	VBN
cord-353633-a4pu6rlu	438	10	dietary	dietary	JJ
cord-353633-a4pu6rlu	438	11	intake	intake	NN
cord-353633-a4pu6rlu	438	12	of	of	IN
cord-353633-a4pu6rlu	438	13	TG	TG	NNP
cord-353633-a4pu6rlu	438	14	and	and	CC
cord-353633-a4pu6rlu	438	15	the	the	DT
cord-353633-a4pu6rlu	438	16	upregulated	upregulate	VBN
cord-353633-a4pu6rlu	438	17	de	de	FW
cord-353633-a4pu6rlu	438	18	novo	novo	NNP
cord-353633-a4pu6rlu	438	19	lipogenesis	lipogenesi	NNS
cord-353633-a4pu6rlu	438	20	observed	observe	VBN
cord-353633-a4pu6rlu	438	21	in	in	IN
cord-353633-a4pu6rlu	438	22	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	438	23	leads	lead	VBZ
cord-353633-a4pu6rlu	438	24	to	to	IN
cord-353633-a4pu6rlu	438	25	elevated	elevated	JJ
cord-353633-a4pu6rlu	438	26	SFA	SFA	NNP
cord-353633-a4pu6rlu	438	27	,	,	,
cord-353633-a4pu6rlu	438	28	LPC	LPC	NNP
cord-353633-a4pu6rlu	438	29	,	,	,
cord-353633-a4pu6rlu	438	30	Ceramides	Ceramides	NNP
cord-353633-a4pu6rlu	438	31	and	and	CC
cord-353633-a4pu6rlu	438	32	ω6	ω6	NN
cord-353633-a4pu6rlu	438	33	/	/	SYM
cord-353633-a4pu6rlu	438	34	ω3	ω3	JJ
cord-353633-a4pu6rlu	438	35	PUFA	pufa	NN
cord-353633-a4pu6rlu	438	36	ratio	ratio	NN
cord-353633-a4pu6rlu	438	37	.	.	.
cord-353633-a4pu6rlu	439	1	SFA	SFA	NNP
cord-353633-a4pu6rlu	439	2	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	439	3	the	the	DT
cord-353633-a4pu6rlu	439	4	secretion	secretion	NN
cord-353633-a4pu6rlu	439	5	of	of	IN
cord-353633-a4pu6rlu	439	6	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	439	7	cytokines	cytokine	NNS
cord-353633-a4pu6rlu	439	8	via	via	IN
cord-353633-a4pu6rlu	439	9	TLR4	TLR4	NNP
cord-353633-a4pu6rlu	439	10	and	and	CC
cord-353633-a4pu6rlu	439	11	apoptosis	apoptosis	NN
cord-353633-a4pu6rlu	439	12	via	via	IN
cord-353633-a4pu6rlu	439	13	TRAIL2	TRAIL2	NNP
cord-353633-a4pu6rlu	439	14	,	,	,
cord-353633-a4pu6rlu	439	15	whereas	whereas	IN
cord-353633-a4pu6rlu	439	16	they	-PRON-	PRP
cord-353633-a4pu6rlu	439	17	increase	increase	VBP
cord-353633-a4pu6rlu	439	18	oxidative	oxidative	JJ
cord-353633-a4pu6rlu	439	19	stress	stress	NN
cord-353633-a4pu6rlu	439	20	,	,	,
cord-353633-a4pu6rlu	439	21	ER	ER	NNP
cord-353633-a4pu6rlu	439	22	stress	stress	NN
cord-353633-a4pu6rlu	439	23	and	and	CC
cord-353633-a4pu6rlu	439	24	impair	impair	VB
cord-353633-a4pu6rlu	439	25	β	β	NN
cord-353633-a4pu6rlu	439	26	-	-	HYPH
cord-353633-a4pu6rlu	439	27	oxidation	oxidation	NN
cord-353633-a4pu6rlu	439	28	in	in	IN
cord-353633-a4pu6rlu	439	29	the	the	DT
cord-353633-a4pu6rlu	439	30	mitochondria	mitochondrion	NNS
cord-353633-a4pu6rlu	439	31	of	of	IN
cord-353633-a4pu6rlu	439	32	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	439	33	.	.	.
cord-353633-a4pu6rlu	440	1	In	in	IN
cord-353633-a4pu6rlu	440	2	stellate	stellate	JJ
cord-353633-a4pu6rlu	440	3	cells	cell	NNS
cord-353633-a4pu6rlu	440	4	,	,	,
cord-353633-a4pu6rlu	440	5	they	-PRON-	PRP
cord-353633-a4pu6rlu	440	6	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	440	7	macrophage	macrophage	NN
cord-353633-a4pu6rlu	440	8	recruitment	recruitment	NN
cord-353633-a4pu6rlu	440	9	,	,	,
cord-353633-a4pu6rlu	440	10	whereas	whereas	IN
cord-353633-a4pu6rlu	440	11	in	in	IN
cord-353633-a4pu6rlu	440	12	Kupffer	Kupffer	NNP
cord-353633-a4pu6rlu	440	13	cells	cell	NNS
cord-353633-a4pu6rlu	440	14	and	and	CC
cord-353633-a4pu6rlu	440	15	macrophages	macrophage	NNS
cord-353633-a4pu6rlu	440	16	SFA	SFA	NNP
cord-353633-a4pu6rlu	440	17	induce	induce	VBP
cord-353633-a4pu6rlu	440	18	their	-PRON-	PRP$
cord-353633-a4pu6rlu	440	19	polarization	polarization	NN
cord-353633-a4pu6rlu	440	20	to	to	IN
cord-353633-a4pu6rlu	440	21	the	the	DT
cord-353633-a4pu6rlu	440	22	M1	M1	NNP
cord-353633-a4pu6rlu	440	23	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	440	24	state	state	NN
cord-353633-a4pu6rlu	440	25	.	.	.
cord-353633-a4pu6rlu	441	1	Increased	increase	VBN
cord-353633-a4pu6rlu	441	2	activation	activation	NN
cord-353633-a4pu6rlu	441	3	of	of	IN
cord-353633-a4pu6rlu	441	4	PLA2	PLA2	NNP
cord-353633-a4pu6rlu	441	5	enzyme	enzyme	NN
cord-353633-a4pu6rlu	441	6	leads	lead	VBZ
cord-353633-a4pu6rlu	441	7	to	to	IN
cord-353633-a4pu6rlu	441	8	formation	formation	NN
cord-353633-a4pu6rlu	441	9	of	of	IN
cord-353633-a4pu6rlu	441	10	LPC	LPC	NNP
cord-353633-a4pu6rlu	441	11	and	and	CC
cord-353633-a4pu6rlu	441	12	depletion	depletion	NN
cord-353633-a4pu6rlu	441	13	of	of	IN
cord-353633-a4pu6rlu	441	14	PC	pc	NN
cord-353633-a4pu6rlu	441	15	.	.	.
cord-353633-a4pu6rlu	442	1	PC	pc	NN
cord-353633-a4pu6rlu	442	2	are	be	VBP
cord-353633-a4pu6rlu	442	3	important	important	JJ
cord-353633-a4pu6rlu	442	4	for	for	IN
cord-353633-a4pu6rlu	442	5	lipid	lipid	NN
cord-353633-a4pu6rlu	442	6	droplet	droplet	NN
cord-353633-a4pu6rlu	442	7	stability	stability	NN
cord-353633-a4pu6rlu	442	8	and	and	CC
cord-353633-a4pu6rlu	442	9	their	-PRON-	PRP$
cord-353633-a4pu6rlu	442	10	deficiency	deficiency	NN
cord-353633-a4pu6rlu	442	11	leads	lead	VBZ
cord-353633-a4pu6rlu	442	12	to	to	IN
cord-353633-a4pu6rlu	442	13	large	large	JJ
cord-353633-a4pu6rlu	442	14	droplet	droplet	NN
cord-353633-a4pu6rlu	442	15	formation	formation	NN
cord-353633-a4pu6rlu	442	16	and	and	CC
cord-353633-a4pu6rlu	442	17	inadequate	inadequate	JJ
cord-353633-a4pu6rlu	442	18	VLDL	vldl	NN
cord-353633-a4pu6rlu	442	19	secretion	secretion	NN
cord-353633-a4pu6rlu	442	20	.	.	.
cord-353633-a4pu6rlu	443	1	High	high	JJ
cord-353633-a4pu6rlu	443	2	LPC	LPC	NNP
cord-353633-a4pu6rlu	443	3	are	be	VBP
cord-353633-a4pu6rlu	443	4	also	also	RB
cord-353633-a4pu6rlu	443	5	triggering	trigger	VBG
cord-353633-a4pu6rlu	443	6	mechanisms	mechanism	NNS
cord-353633-a4pu6rlu	443	7	of	of	IN
cord-353633-a4pu6rlu	443	8	impaired	impaired	JJ
cord-353633-a4pu6rlu	443	9	β	β	NN
cord-353633-a4pu6rlu	443	10	-	-	HYPH
cord-353633-a4pu6rlu	443	11	oxidation	oxidation	NN
cord-353633-a4pu6rlu	443	12	,	,	,
cord-353633-a4pu6rlu	443	13	apoptosis	apoptosis	NN
cord-353633-a4pu6rlu	443	14	,	,	,
cord-353633-a4pu6rlu	443	15	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	443	16	and	and	CC
cord-353633-a4pu6rlu	443	17	HCC	HCC	NNP
cord-353633-a4pu6rlu	443	18	.	.	.
cord-353633-a4pu6rlu	444	1	High	high	JJ
cord-353633-a4pu6rlu	444	2	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	444	3	ceramide	ceramide	NN
cord-353633-a4pu6rlu	444	4	concentrations	concentration	NNS
cord-353633-a4pu6rlu	444	5	increase	increase	VBP
cord-353633-a4pu6rlu	444	6	cholesterol	cholesterol	NN
cord-353633-a4pu6rlu	444	7	synthesis	synthesis	NN
cord-353633-a4pu6rlu	444	8	and	and	CC
cord-353633-a4pu6rlu	444	9	TG	TG	NNP
cord-353633-a4pu6rlu	444	10	accumulation	accumulation	NN
cord-353633-a4pu6rlu	444	11	,	,	,
cord-353633-a4pu6rlu	444	12	promote	promote	VB
cord-353633-a4pu6rlu	444	13	insulin	insulin	NN
cord-353633-a4pu6rlu	444	14	resistance	resistance	NN
cord-353633-a4pu6rlu	444	15	by	by	IN
cord-353633-a4pu6rlu	444	16	blocking	block	VBG
cord-353633-a4pu6rlu	444	17	Akt	Akt	NNP
cord-353633-a4pu6rlu	444	18	-	-	HYPH
cord-353633-a4pu6rlu	444	19	mediated	mediate	VBN
cord-353633-a4pu6rlu	444	20	insulin	insulin	NN
cord-353633-a4pu6rlu	444	21	signaling	signaling	NN
cord-353633-a4pu6rlu	444	22	,	,	,
cord-353633-a4pu6rlu	444	23	induce	induce	VB
cord-353633-a4pu6rlu	444	24	the	the	DT
cord-353633-a4pu6rlu	444	25	secretion	secretion	NN
cord-353633-a4pu6rlu	444	26	of	of	IN
cord-353633-a4pu6rlu	444	27	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	444	28	cytokines	cytokine	NNS
cord-353633-a4pu6rlu	444	29	and	and	CC
cord-353633-a4pu6rlu	444	30	stimulate	stimulate	VBP
cord-353633-a4pu6rlu	444	31	apoptosis	apoptosis	NN
cord-353633-a4pu6rlu	444	32	by	by	IN
cord-353633-a4pu6rlu	444	33	increasing	increase	VBG
cord-353633-a4pu6rlu	444	34	ROS	ROS	NNP
cord-353633-a4pu6rlu	444	35	generation	generation	NN
cord-353633-a4pu6rlu	444	36	,	,	,
cord-353633-a4pu6rlu	444	37	ER	ER	NNP
cord-353633-a4pu6rlu	444	38	stress	stress	NN
cord-353633-a4pu6rlu	444	39	and	and	CC
cord-353633-a4pu6rlu	444	40	β	β	NN
cord-353633-a4pu6rlu	444	41	-	-	HYPH
cord-353633-a4pu6rlu	444	42	oxidation	oxidation	NN
cord-353633-a4pu6rlu	444	43	impairment	impairment	NN
cord-353633-a4pu6rlu	444	44	.	.	.
cord-353633-a4pu6rlu	445	1	In	in	IN
cord-353633-a4pu6rlu	445	2	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	445	3	stellate	stellate	JJ
cord-353633-a4pu6rlu	445	4	cells	cell	NNS
cord-353633-a4pu6rlu	445	5	,	,	,
cord-353633-a4pu6rlu	445	6	they	-PRON-	PRP
cord-353633-a4pu6rlu	445	7	increase	increase	VBP
cord-353633-a4pu6rlu	445	8	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	445	9	matrix	matrix	NN
cord-353633-a4pu6rlu	445	10	deposition	deposition	NN
cord-353633-a4pu6rlu	445	11	and	and	CC
cord-353633-a4pu6rlu	445	12	pro	pro	JJ
cord-353633-a4pu6rlu	445	13	-	-	JJ
cord-353633-a4pu6rlu	445	14	angiogenic	angiogenic	JJ
cord-353633-a4pu6rlu	445	15	factors	factor	NNS
cord-353633-a4pu6rlu	445	16	secretion	secretion	NN
cord-353633-a4pu6rlu	445	17	promoting	promote	VBG
cord-353633-a4pu6rlu	445	18	fibrogenesis	fibrogenesis	NN
cord-353633-a4pu6rlu	445	19	.	.	.
cord-353633-a4pu6rlu	446	1	Finally	finally	RB
cord-353633-a4pu6rlu	446	2	,	,	,
cord-353633-a4pu6rlu	446	3	the	the	DT
cord-353633-a4pu6rlu	446	4	high	high	JJ
cord-353633-a4pu6rlu	446	5	ω6	ω6	NN
cord-353633-a4pu6rlu	446	6	/	/	SYM
cord-353633-a4pu6rlu	446	7	ω3	ω3	NNP
cord-353633-a4pu6rlu	446	8	ratio	ratio	NN
cord-353633-a4pu6rlu	446	9	leads	lead	VBZ
cord-353633-a4pu6rlu	446	10	to	to	IN
cord-353633-a4pu6rlu	446	11	increased	increase	VBN
cord-353633-a4pu6rlu	446	12	synthesis	synthesis	NN
cord-353633-a4pu6rlu	446	13	of	of	IN
cord-353633-a4pu6rlu	446	14	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	446	15	molecules	molecule	NNS
cord-353633-a4pu6rlu	446	16	,	,	,
cord-353633-a4pu6rlu	446	17	such	such	JJ
cord-353633-a4pu6rlu	446	18	as	as	IN
cord-353633-a4pu6rlu	446	19	prostaglandins	prostaglandin	NNS
cord-353633-a4pu6rlu	446	20	,	,	,
cord-353633-a4pu6rlu	446	21	leukotrienes	leukotriene	NNS
cord-353633-a4pu6rlu	446	22	,	,	,
cord-353633-a4pu6rlu	446	23	thromboxanes	thromboxane	NNS
cord-353633-a4pu6rlu	446	24	in	in	IN
cord-353633-a4pu6rlu	446	25	expense	expense	NN
cord-353633-a4pu6rlu	446	26	of	of	IN
cord-353633-a4pu6rlu	446	27	the	the	DT
cord-353633-a4pu6rlu	446	28	synthesis	synthesis	NN
cord-353633-a4pu6rlu	446	29	of	of	IN
cord-353633-a4pu6rlu	446	30	anti	anti	JJ
cord-353633-a4pu6rlu	446	31	-	-	JJ
cord-353633-a4pu6rlu	446	32	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	446	33	SPMs	spm	NNS
cord-353633-a4pu6rlu	446	34	,	,	,
cord-353633-a4pu6rlu	446	35	thus	thus	RB
cord-353633-a4pu6rlu	446	36	resulting	result	VBG
cord-353633-a4pu6rlu	446	37	in	in	IN
cord-353633-a4pu6rlu	446	38	a	a	DT
cord-353633-a4pu6rlu	446	39	pro	pro	JJ
cord-353633-a4pu6rlu	446	40	-	-	JJ
cord-353633-a4pu6rlu	446	41	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	446	42	Complications	complication	NNS
cord-353633-a4pu6rlu	446	43	,	,	,
cord-353633-a4pu6rlu	446	44	morbidity	morbidity	NN
cord-353633-a4pu6rlu	446	45	and	and	CC
cord-353633-a4pu6rlu	446	46	mortality	mortality	NN
cord-353633-a4pu6rlu	446	47	of	of	IN
cord-353633-a4pu6rlu	446	48	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	446	49	fatty	fatty	JJ
cord-353633-a4pu6rlu	446	50	liver	liver	NN
cord-353633-a4pu6rlu	446	51	disease	disease	NN
cord-353633-a4pu6rlu	447	1	The	the	DT
cord-353633-a4pu6rlu	447	2	multiple	multiple	JJ
cord-353633-a4pu6rlu	447	3	-	-	HYPH
cord-353633-a4pu6rlu	447	4	hit	hit	VBN
cord-353633-a4pu6rlu	447	5	pathogenesis	pathogenesis	NN
cord-353633-a4pu6rlu	447	6	of	of	IN
cord-353633-a4pu6rlu	447	7	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	447	8	fatty	fatty	JJ
cord-353633-a4pu6rlu	447	9	liver	liver	NN
cord-353633-a4pu6rlu	447	10	disease	disease	NN
cord-353633-a4pu6rlu	447	11	(	(	-LRB-
cord-353633-a4pu6rlu	447	12	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	447	13	)	)	-RRB-
cord-353633-a4pu6rlu	448	1	Established	establish	VBN
cord-353633-a4pu6rlu	448	2	and	and	CC
cord-353633-a4pu6rlu	448	3	emerging	emerge	VBG
cord-353633-a4pu6rlu	448	4	factors	factor	NNS
cord-353633-a4pu6rlu	448	5	affecting	affect	VBG
cord-353633-a4pu6rlu	448	6	the	the	DT
cord-353633-a4pu6rlu	448	7	progression	progression	NN
cord-353633-a4pu6rlu	448	8	of	of	IN
cord-353633-a4pu6rlu	448	9	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	448	10	fatty	fatty	JJ
cord-353633-a4pu6rlu	448	11	liver	liver	NN
cord-353633-a4pu6rlu	448	12	disease	disease	NN
cord-353633-a4pu6rlu	448	13	Diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	448	14	accuracy	accuracy	NN
cord-353633-a4pu6rlu	448	15	and	and	CC
cord-353633-a4pu6rlu	448	16	reliability	reliability	NN
cord-353633-a4pu6rlu	448	17	of	of	IN
cord-353633-a4pu6rlu	448	18	ultrasonography	ultrasonography	NN
cord-353633-a4pu6rlu	448	19	for	for	IN
cord-353633-a4pu6rlu	448	20	the	the	DT
cord-353633-a4pu6rlu	448	21	detection	detection	NN
cord-353633-a4pu6rlu	448	22	of	of	IN
cord-353633-a4pu6rlu	448	23	fatty	fatty	JJ
cord-353633-a4pu6rlu	448	24	liver	liver	NN
cord-353633-a4pu6rlu	448	25	:	:	:
cord-353633-a4pu6rlu	448	26	a	a	DT
cord-353633-a4pu6rlu	448	27	meta	meta	JJ
cord-353633-a4pu6rlu	448	28	-	-	HYPH
cord-353633-a4pu6rlu	448	29	analysis	analysis	NN
cord-353633-a4pu6rlu	448	30	Clinical	clinical	JJ
cord-353633-a4pu6rlu	448	31	value	value	NN
cord-353633-a4pu6rlu	448	32	of	of	IN
cord-353633-a4pu6rlu	448	33	liver	liver	NN
cord-353633-a4pu6rlu	448	34	ultrasound	ultrasound	NN
cord-353633-a4pu6rlu	448	35	for	for	IN
cord-353633-a4pu6rlu	448	36	the	the	DT
cord-353633-a4pu6rlu	448	37	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	448	38	of	of	IN
cord-353633-a4pu6rlu	448	39	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	448	40	fatty	fatty	JJ
cord-353633-a4pu6rlu	448	41	liver	liver	NN
cord-353633-a4pu6rlu	448	42	disease	disease	NN
cord-353633-a4pu6rlu	448	43	in	in	IN
cord-353633-a4pu6rlu	448	44	overweight	overweight	JJ
cord-353633-a4pu6rlu	448	45	and	and	CC
cord-353633-a4pu6rlu	448	46	obese	obese	JJ
cord-353633-a4pu6rlu	448	47	patients	patient	NNS
cord-353633-a4pu6rlu	448	48	Non	non	JJ
cord-353633-a4pu6rlu	448	49	-	-	JJ
cord-353633-a4pu6rlu	448	50	invasive	invasive	JJ
cord-353633-a4pu6rlu	448	51	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	448	52	of	of	IN
cord-353633-a4pu6rlu	448	53	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	448	54	steatosis	steatosis	NN
cord-353633-a4pu6rlu	448	55	Individual	individual	JJ
cord-353633-a4pu6rlu	448	56	patient	patient	NN
cord-353633-a4pu6rlu	448	57	data	datum	NNS
cord-353633-a4pu6rlu	448	58	meta	meta	NN
cord-353633-a4pu6rlu	448	59	-	-	HYPH
cord-353633-a4pu6rlu	448	60	analysis	analysis	NN
cord-353633-a4pu6rlu	448	61	of	of	IN
cord-353633-a4pu6rlu	448	62	controlled	control	VBN
cord-353633-a4pu6rlu	448	63	attenuation	attenuation	NN
cord-353633-a4pu6rlu	448	64	parameter	parameter	NN
cord-353633-a4pu6rlu	448	65	(	(	-LRB-
cord-353633-a4pu6rlu	448	66	CAP	cap	NN
cord-353633-a4pu6rlu	448	67	)	)	-RRB-
cord-353633-a4pu6rlu	448	68	technology	technology	NN
cord-353633-a4pu6rlu	448	69	for	for	IN
cord-353633-a4pu6rlu	448	70	assessing	assess	VBG
cord-353633-a4pu6rlu	448	71	steatosis	steatosis	NN
cord-353633-a4pu6rlu	448	72	Controlled	control	VBN
cord-353633-a4pu6rlu	448	73	Attenuation	attenuation	NN
cord-353633-a4pu6rlu	448	74	Parameter	parameter	NN
cord-353633-a4pu6rlu	448	75	(	(	-LRB-
cord-353633-a4pu6rlu	448	76	CAP	cap	NN
cord-353633-a4pu6rlu	448	77	)	)	-RRB-
cord-353633-a4pu6rlu	448	78	with	with	IN
cord-353633-a4pu6rlu	448	79	the	the	DT
cord-353633-a4pu6rlu	448	80	XL	XL	NNP
cord-353633-a4pu6rlu	448	81	Probe	Probe	NNP
cord-353633-a4pu6rlu	448	82	of	of	IN
cord-353633-a4pu6rlu	448	83	the	the	DT
cord-353633-a4pu6rlu	448	84	Fibroscan((R	Fibroscan((R	NNPS
cord-353633-a4pu6rlu	448	85	)	)	-RRB-
cord-353633-a4pu6rlu	448	86	)	)	-RRB-
cord-353633-a4pu6rlu	449	1	:	:	:
cord-353633-a4pu6rlu	449	2	A	a	DT
cord-353633-a4pu6rlu	449	3	Comparative	Comparative	NNP
cord-353633-a4pu6rlu	449	4	Study	Study	NNP
cord-353633-a4pu6rlu	449	5	with	with	IN
cord-353633-a4pu6rlu	449	6	the	the	DT
cord-353633-a4pu6rlu	449	7	M	M	NNP
cord-353633-a4pu6rlu	449	8	Probe	Probe	NNP
cord-353633-a4pu6rlu	449	9	and	and	CC
cord-353633-a4pu6rlu	449	10	Liver	Liver	NNP
cord-353633-a4pu6rlu	449	11	Biopsy	Biopsy	NNP
cord-353633-a4pu6rlu	449	12	Diagnostic	Diagnostic	NNP
cord-353633-a4pu6rlu	449	13	value	value	NN
cord-353633-a4pu6rlu	449	14	of	of	IN
cord-353633-a4pu6rlu	449	15	MRI	MRI	NNP
cord-353633-a4pu6rlu	449	16	-	-	HYPH
cord-353633-a4pu6rlu	449	17	PDFF	PDFF	NNP
cord-353633-a4pu6rlu	449	18	for	for	IN
cord-353633-a4pu6rlu	449	19	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	449	20	steatosis	steatosis	NN
cord-353633-a4pu6rlu	449	21	in	in	IN
cord-353633-a4pu6rlu	449	22	patients	patient	NNS
cord-353633-a4pu6rlu	449	23	with	with	IN
cord-353633-a4pu6rlu	449	24	non	non	JJ
cord-353633-a4pu6rlu	449	25	-	-	JJ
cord-353633-a4pu6rlu	449	26	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	449	27	fatty	fatty	JJ
cord-353633-a4pu6rlu	449	28	liver	liver	NN
cord-353633-a4pu6rlu	449	29	disease	disease	NN
cord-353633-a4pu6rlu	449	30	:	:	:
cord-353633-a4pu6rlu	449	31	a	a	DT
cord-353633-a4pu6rlu	449	32	metaanalysis	metaanalysis	NN
cord-353633-a4pu6rlu	449	33	Noninvasive	Noninvasive	NNP
cord-353633-a4pu6rlu	449	34	Assessment	Assessment	NNP
cord-353633-a4pu6rlu	449	35	of	of	IN
cord-353633-a4pu6rlu	449	36	Liver	Liver	NNP
cord-353633-a4pu6rlu	449	37	Disease	Disease	NNP
cord-353633-a4pu6rlu	449	38	in	in	IN
cord-353633-a4pu6rlu	449	39	Patients	patient	NNS
cord-353633-a4pu6rlu	449	40	With	with	IN
cord-353633-a4pu6rlu	449	41	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	449	42	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	449	43	Liver	Liver	NNP
cord-353633-a4pu6rlu	449	44	Disease	Disease	NNP
cord-353633-a4pu6rlu	449	45	Advances	advance	VBZ
cord-353633-a4pu6rlu	449	46	in	in	IN
cord-353633-a4pu6rlu	449	47	non	non	JJ
cord-353633-a4pu6rlu	449	48	-	-	JJ
cord-353633-a4pu6rlu	449	49	invasive	invasive	JJ
cord-353633-a4pu6rlu	449	50	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	449	51	for	for	IN
cord-353633-a4pu6rlu	449	52	the	the	DT
cord-353633-a4pu6rlu	449	53	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	449	54	and	and	CC
cord-353633-a4pu6rlu	449	55	monitoring	monitoring	NN
cord-353633-a4pu6rlu	449	56	of	of	IN
cord-353633-a4pu6rlu	449	57	non	non	JJ
cord-353633-a4pu6rlu	449	58	-	-	JJ
cord-353633-a4pu6rlu	449	59	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	449	60	fatty	fatty	JJ
cord-353633-a4pu6rlu	449	61	liver	liver	NN
cord-353633-a4pu6rlu	449	62	disease	disease	NN
cord-353633-a4pu6rlu	449	63	Diagnostic	Diagnostic	NNP
cord-353633-a4pu6rlu	449	64	Value	Value	NNP
cord-353633-a4pu6rlu	449	65	of	of	IN
cord-353633-a4pu6rlu	449	66	CK-18	CK-18	NNP
cord-353633-a4pu6rlu	449	67	,	,	,
cord-353633-a4pu6rlu	449	68	FGF-21	FGF-21	NNP
cord-353633-a4pu6rlu	449	69	,	,	,
cord-353633-a4pu6rlu	449	70	and	and	CC
cord-353633-a4pu6rlu	449	71	Related	Related	NNP
cord-353633-a4pu6rlu	449	72	Biomarker	Biomarker	NNP
cord-353633-a4pu6rlu	449	73	Panel	Panel	NNP
cord-353633-a4pu6rlu	449	74	in	in	IN
cord-353633-a4pu6rlu	449	75	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	449	76	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	449	77	Liver	Liver	NNP
cord-353633-a4pu6rlu	449	78	Disease	Disease	NNP
cord-353633-a4pu6rlu	449	79	:	:	:
cord-353633-a4pu6rlu	450	1	A	a	DT
cord-353633-a4pu6rlu	450	2	Systematic	Systematic	NNP
cord-353633-a4pu6rlu	450	3	Review	Review	NNP
cord-353633-a4pu6rlu	450	4	and	and	CC
cord-353633-a4pu6rlu	450	5	Meta	Meta	NNP
cord-353633-a4pu6rlu	450	6	-	-	HYPH
cord-353633-a4pu6rlu	450	7	Analysis	Analysis	NNP
cord-353633-a4pu6rlu	450	8	Limited	limited	JJ
cord-353633-a4pu6rlu	450	9	value	value	NN
cord-353633-a4pu6rlu	450	10	of	of	IN
cord-353633-a4pu6rlu	450	11	plasma	plasma	NN
cord-353633-a4pu6rlu	450	12	cytokeratin-18	cytokeratin-18	NN
cord-353633-a4pu6rlu	450	13	as	as	IN
cord-353633-a4pu6rlu	450	14	a	a	DT
cord-353633-a4pu6rlu	450	15	biomarker	biomarker	NN
cord-353633-a4pu6rlu	450	16	for	for	IN
cord-353633-a4pu6rlu	450	17	NASH	NASH	NNP
cord-353633-a4pu6rlu	450	18	and	and	CC
cord-353633-a4pu6rlu	450	19	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	450	20	in	in	IN
cord-353633-a4pu6rlu	450	21	patients	patient	NNS
cord-353633-a4pu6rlu	450	22	with	with	IN
cord-353633-a4pu6rlu	450	23	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	450	24	fatty	fatty	JJ
cord-353633-a4pu6rlu	450	25	liver	liver	NN
cord-353633-a4pu6rlu	450	26	disease	disease	NN
cord-353633-a4pu6rlu	450	27	PNPLA3	PNPLA3	NNP
cord-353633-a4pu6rlu	450	28	,	,	,
cord-353633-a4pu6rlu	450	29	the	the	DT
cord-353633-a4pu6rlu	450	30	triacylglycerol	triacylglycerol	JJ
cord-353633-a4pu6rlu	450	31	synthesis	synthesis	NN
cord-353633-a4pu6rlu	450	32	/	/	SYM
cord-353633-a4pu6rlu	450	33	hydrolysis	hydrolysis	NN
cord-353633-a4pu6rlu	450	34	/	/	SYM
cord-353633-a4pu6rlu	450	35	storage	storage	NN
cord-353633-a4pu6rlu	450	36	dilemma	dilemma	NN
cord-353633-a4pu6rlu	450	37	,	,	,
cord-353633-a4pu6rlu	450	38	and	and	CC
cord-353633-a4pu6rlu	450	39	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	450	40	fatty	fatty	JJ
cord-353633-a4pu6rlu	450	41	liver	liver	NN
cord-353633-a4pu6rlu	450	42	disease	disease	NN
cord-353633-a4pu6rlu	450	43	Human	Human	NNP
cord-353633-a4pu6rlu	450	44	PNPLA3-I148	PNPLA3-I148	NNP
cord-353633-a4pu6rlu	450	45	M	M	NNP
cord-353633-a4pu6rlu	450	46	variant	variant	NN
cord-353633-a4pu6rlu	450	47	increases	increase	VBZ
cord-353633-a4pu6rlu	451	1	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	451	2	retention	retention	NN
cord-353633-a4pu6rlu	451	3	of	of	IN
cord-353633-a4pu6rlu	451	4	polyunsaturated	polyunsaturated	JJ
cord-353633-a4pu6rlu	451	5	fatty	fatty	JJ
cord-353633-a4pu6rlu	451	6	acids	acid	NNS
cord-353633-a4pu6rlu	451	7	Genetic	genetic	JJ
cord-353633-a4pu6rlu	451	8	variation	variation	NN
cord-353633-a4pu6rlu	451	9	in	in	IN
cord-353633-a4pu6rlu	451	10	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	451	11	confers	confer	VBZ
cord-353633-a4pu6rlu	451	12	susceptibility	susceptibility	NN
cord-353633-a4pu6rlu	451	13	to	to	IN
cord-353633-a4pu6rlu	451	14	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	451	15	fatty	fatty	JJ
cord-353633-a4pu6rlu	451	16	liver	liver	NN
cord-353633-a4pu6rlu	451	17	disease	disease	NN
cord-353633-a4pu6rlu	452	1	A	a	DT
cord-353633-a4pu6rlu	452	2	common	common	JJ
cord-353633-a4pu6rlu	452	3	variant	variant	NN
cord-353633-a4pu6rlu	452	4	in	in	IN
cord-353633-a4pu6rlu	452	5	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	452	6	is	be	VBZ
cord-353633-a4pu6rlu	452	7	associated	associate	VBN
cord-353633-a4pu6rlu	452	8	with	with	IN
cord-353633-a4pu6rlu	452	9	age	age	NN
cord-353633-a4pu6rlu	452	10	at	at	IN
cord-353633-a4pu6rlu	452	11	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	452	12	of	of	IN
cord-353633-a4pu6rlu	452	13	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	452	14	in	in	IN
cord-353633-a4pu6rlu	452	15	patients	patient	NNS
cord-353633-a4pu6rlu	452	16	from	from	IN
cord-353633-a4pu6rlu	452	17	a	a	DT
cord-353633-a4pu6rlu	452	18	multi	multi	JJ
cord-353633-a4pu6rlu	452	19	-	-	JJ
cord-353633-a4pu6rlu	452	20	ethnic	ethnic	JJ
cord-353633-a4pu6rlu	452	21	biobank	biobank	NNP
cord-353633-a4pu6rlu	452	22	Association	Association	NNP
cord-353633-a4pu6rlu	452	23	between	between	IN
cord-353633-a4pu6rlu	452	24	patatin	patatin	NNP
cord-353633-a4pu6rlu	452	25	-	-	HYPH
cord-353633-a4pu6rlu	452	26	like	like	JJ
cord-353633-a4pu6rlu	452	27	phospholipase	phospholipase	NN
cord-353633-a4pu6rlu	452	28	domain	domain	NN
cord-353633-a4pu6rlu	452	29	containing	contain	VBG
cord-353633-a4pu6rlu	452	30	3	3	CD
cord-353633-a4pu6rlu	452	31	gene	gene	NN
cord-353633-a4pu6rlu	452	32	(	(	-LRB-
cord-353633-a4pu6rlu	452	33	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	452	34	)	)	-RRB-
cord-353633-a4pu6rlu	452	35	polymorphisms	polymorphism	NNS
cord-353633-a4pu6rlu	452	36	and	and	CC
cord-353633-a4pu6rlu	452	37	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	452	38	fatty	fatty	JJ
cord-353633-a4pu6rlu	452	39	liver	liver	NN
cord-353633-a4pu6rlu	452	40	disease	disease	NN
cord-353633-a4pu6rlu	452	41	:	:	:
cord-353633-a4pu6rlu	452	42	a	a	DT
cord-353633-a4pu6rlu	452	43	HuGE	HuGE	NNP
cord-353633-a4pu6rlu	452	44	review	review	NN
cord-353633-a4pu6rlu	452	45	and	and	CC
cord-353633-a4pu6rlu	452	46	meta	meta	NNP
cord-353633-a4pu6rlu	452	47	-	-	HYPH
cord-353633-a4pu6rlu	452	48	analysis	analysis	NNP
cord-353633-a4pu6rlu	452	49	Genome	Genome	NNP
cord-353633-a4pu6rlu	452	50	-	-	HYPH
cord-353633-a4pu6rlu	452	51	wide	wide	JJ
cord-353633-a4pu6rlu	452	52	scan	scan	NN
cord-353633-a4pu6rlu	453	1	revealed	reveal	VBD
cord-353633-a4pu6rlu	453	2	that	that	IN
cord-353633-a4pu6rlu	453	3	polymorphisms	polymorphism	NNS
cord-353633-a4pu6rlu	453	4	in	in	IN
cord-353633-a4pu6rlu	453	5	the	the	DT
cord-353633-a4pu6rlu	453	6	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	453	7	,	,	,
cord-353633-a4pu6rlu	453	8	SAMM50	samm50	XX
cord-353633-a4pu6rlu	453	9	,	,	,
cord-353633-a4pu6rlu	453	10	and	and	CC
cord-353633-a4pu6rlu	453	11	PARVB	PARVB	NNP
cord-353633-a4pu6rlu	453	12	genes	gene	NNS
cord-353633-a4pu6rlu	453	13	are	be	VBP
cord-353633-a4pu6rlu	453	14	associated	associate	VBN
cord-353633-a4pu6rlu	453	15	with	with	IN
cord-353633-a4pu6rlu	453	16	development	development	NN
cord-353633-a4pu6rlu	453	17	and	and	CC
cord-353633-a4pu6rlu	453	18	progression	progression	NN
cord-353633-a4pu6rlu	453	19	of	of	IN
cord-353633-a4pu6rlu	453	20	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	453	21	fatty	fatty	JJ
cord-353633-a4pu6rlu	453	22	liver	liver	NN
cord-353633-a4pu6rlu	453	23	disease	disease	NN
cord-353633-a4pu6rlu	453	24	in	in	IN
cord-353633-a4pu6rlu	453	25	Japan	Japan	NNP
cord-353633-a4pu6rlu	453	26	Genome	Genome	NNP
cord-353633-a4pu6rlu	453	27	-	-	HYPH
cord-353633-a4pu6rlu	453	28	wide	wide	NNP
cord-353633-a4pu6rlu	453	29	association	association	NN
cord-353633-a4pu6rlu	453	30	analysis	analysis	NN
cord-353633-a4pu6rlu	453	31	identifies	identify	VBZ
cord-353633-a4pu6rlu	453	32	variants	variant	NNS
cord-353633-a4pu6rlu	453	33	associated	associate	VBN
cord-353633-a4pu6rlu	453	34	with	with	IN
cord-353633-a4pu6rlu	453	35	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	453	36	fatty	fatty	JJ
cord-353633-a4pu6rlu	453	37	liver	liver	NN
cord-353633-a4pu6rlu	453	38	disease	disease	NN
cord-353633-a4pu6rlu	453	39	that	that	WDT
cord-353633-a4pu6rlu	453	40	have	have	VBP
cord-353633-a4pu6rlu	453	41	distinct	distinct	JJ
cord-353633-a4pu6rlu	453	42	effects	effect	NNS
cord-353633-a4pu6rlu	453	43	on	on	IN
cord-353633-a4pu6rlu	453	44	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	453	45	traits	trait	NNS
cord-353633-a4pu6rlu	453	46	Evaluation	Evaluation	NNP
cord-353633-a4pu6rlu	453	47	of	of	IN
cord-353633-a4pu6rlu	453	48	Polygenic	Polygenic	NNP
cord-353633-a4pu6rlu	453	49	Determinants	Determinants	NNP
cord-353633-a4pu6rlu	453	50	of	of	IN
cord-353633-a4pu6rlu	453	51	Non	non	JJ
cord-353633-a4pu6rlu	453	52	-	-	JJ
cord-353633-a4pu6rlu	453	53	Alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	453	54	Fatty	fatty	JJ
cord-353633-a4pu6rlu	453	55	Liver	liver	NN
cord-353633-a4pu6rlu	453	56	Disease	Disease	NNP
cord-353633-a4pu6rlu	453	57	(	(	-LRB-
cord-353633-a4pu6rlu	453	58	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	453	59	)	)	-RRB-
cord-353633-a4pu6rlu	454	1	By	by	IN
cord-353633-a4pu6rlu	454	2	a	a	DT
cord-353633-a4pu6rlu	454	3	Candidate	Candidate	NNP
cord-353633-a4pu6rlu	454	4	Genes	Genes	NNPS
cord-353633-a4pu6rlu	454	5	Resequencing	Resequencing	NNP
cord-353633-a4pu6rlu	454	6	Strategy	Strategy	NNP
cord-353633-a4pu6rlu	454	7	GWAS	GWAS	NNP
cord-353633-a4pu6rlu	454	8	and	and	CC
cord-353633-a4pu6rlu	454	9	enrichment	enrichment	NN
cord-353633-a4pu6rlu	454	10	analyses	analysis	NNS
cord-353633-a4pu6rlu	454	11	of	of	IN
cord-353633-a4pu6rlu	454	12	non	non	JJ
cord-353633-a4pu6rlu	454	13	-	-	JJ
cord-353633-a4pu6rlu	454	14	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	454	15	fatty	fatty	JJ
cord-353633-a4pu6rlu	454	16	liver	liver	NN
cord-353633-a4pu6rlu	454	17	disease	disease	NN
cord-353633-a4pu6rlu	454	18	identify	identify	VBP
cord-353633-a4pu6rlu	454	19	new	new	JJ
cord-353633-a4pu6rlu	454	20	traitassociated	traitassociated	JJ
cord-353633-a4pu6rlu	454	21	genes	gene	NNS
cord-353633-a4pu6rlu	454	22	and	and	CC
cord-353633-a4pu6rlu	454	23	pathways	pathway	NNS
cord-353633-a4pu6rlu	454	24	across	across	IN
cord-353633-a4pu6rlu	455	1	eMERGE	eMERGE	NNP
cord-353633-a4pu6rlu	455	2	Network	Network	NNP
cord-353633-a4pu6rlu	455	3	A	a	DT
cord-353633-a4pu6rlu	455	4	common	common	JJ
cord-353633-a4pu6rlu	455	5	variant	variant	NN
cord-353633-a4pu6rlu	455	6	in	in	IN
cord-353633-a4pu6rlu	455	7	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	455	8	,	,	,
cord-353633-a4pu6rlu	455	9	which	which	WDT
cord-353633-a4pu6rlu	455	10	encodes	encode	VBZ
cord-353633-a4pu6rlu	455	11	adiponutrin	adiponutrin	NNP
cord-353633-a4pu6rlu	455	12	,	,	,
cord-353633-a4pu6rlu	455	13	is	be	VBZ
cord-353633-a4pu6rlu	455	14	associated	associate	VBN
cord-353633-a4pu6rlu	455	15	with	with	IN
cord-353633-a4pu6rlu	455	16	liver	liver	NN
cord-353633-a4pu6rlu	455	17	fat	fat	NN
cord-353633-a4pu6rlu	455	18	content	content	NN
cord-353633-a4pu6rlu	455	19	in	in	IN
cord-353633-a4pu6rlu	455	20	humans	human	NNS
cord-353633-a4pu6rlu	456	1	A	a	DT
cord-353633-a4pu6rlu	456	2	nonsynonymous	nonsynonymous	JJ
cord-353633-a4pu6rlu	456	3	gene	gene	NN
cord-353633-a4pu6rlu	456	4	variant	variant	NN
cord-353633-a4pu6rlu	456	5	in	in	IN
cord-353633-a4pu6rlu	456	6	the	the	DT
cord-353633-a4pu6rlu	456	7	adiponutrin	adiponutrin	NNP
cord-353633-a4pu6rlu	456	8	gene	gene	NN
cord-353633-a4pu6rlu	456	9	is	be	VBZ
cord-353633-a4pu6rlu	456	10	associated	associate	VBN
cord-353633-a4pu6rlu	456	11	with	with	IN
cord-353633-a4pu6rlu	456	12	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	456	13	fatty	fatty	JJ
cord-353633-a4pu6rlu	456	14	liver	liver	NN
cord-353633-a4pu6rlu	456	15	disease	disease	NN
cord-353633-a4pu6rlu	456	16	severity	severity	NN
cord-353633-a4pu6rlu	456	17	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	456	18	variants	variant	NNS
cord-353633-a4pu6rlu	456	19	specifically	specifically	RB
cord-353633-a4pu6rlu	456	20	confer	confer	VB
cord-353633-a4pu6rlu	456	21	increased	increase	VBN
cord-353633-a4pu6rlu	456	22	risk	risk	NN
cord-353633-a4pu6rlu	456	23	for	for	IN
cord-353633-a4pu6rlu	456	24	histologic	histologic	JJ
cord-353633-a4pu6rlu	456	25	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	456	26	fatty	fatty	JJ
cord-353633-a4pu6rlu	456	27	liver	liver	NN
cord-353633-a4pu6rlu	456	28	disease	disease	NN
cord-353633-a4pu6rlu	456	29	but	but	CC
cord-353633-a4pu6rlu	456	30	not	not	RB
cord-353633-a4pu6rlu	456	31	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	456	32	disease	disease	NN
cord-353633-a4pu6rlu	457	1	The	the	DT
cord-353633-a4pu6rlu	457	2	association	association	NN
cord-353633-a4pu6rlu	457	3	of	of	IN
cord-353633-a4pu6rlu	457	4	genetic	genetic	JJ
cord-353633-a4pu6rlu	457	5	variability	variability	NN
cord-353633-a4pu6rlu	457	6	in	in	IN
cord-353633-a4pu6rlu	457	7	patatin	patatin	JJ
cord-353633-a4pu6rlu	457	8	-	-	HYPH
cord-353633-a4pu6rlu	457	9	like	like	JJ
cord-353633-a4pu6rlu	457	10	phospholipase	phospholipase	NN
cord-353633-a4pu6rlu	457	11	domain	domain	NN
cord-353633-a4pu6rlu	457	12	-	-	HYPH
cord-353633-a4pu6rlu	457	13	containing	contain	VBG
cord-353633-a4pu6rlu	457	14	protein	protein	NN
cord-353633-a4pu6rlu	457	15	3	3	CD
cord-353633-a4pu6rlu	457	16	(	(	-LRB-
cord-353633-a4pu6rlu	457	17	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	457	18	)	)	-RRB-
cord-353633-a4pu6rlu	457	19	with	with	IN
cord-353633-a4pu6rlu	457	20	histological	histological	JJ
cord-353633-a4pu6rlu	457	21	severity	severity	NN
cord-353633-a4pu6rlu	457	22	of	of	IN
cord-353633-a4pu6rlu	457	23	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	457	24	fatty	fatty	JJ
cord-353633-a4pu6rlu	457	25	liver	liver	NN
cord-353633-a4pu6rlu	457	26	disease	disease	NN
cord-353633-a4pu6rlu	457	27	Genetic	genetic	JJ
cord-353633-a4pu6rlu	457	28	polymorphisms	polymorphism	NNS
cord-353633-a4pu6rlu	457	29	of	of	IN
cord-353633-a4pu6rlu	457	30	the	the	DT
cord-353633-a4pu6rlu	457	31	human	human	JJ
cord-353633-a4pu6rlu	457	32	PNPLA3	PNPLA3	NNP
cord-353633-a4pu6rlu	457	33	gene	gene	NN
cord-353633-a4pu6rlu	457	34	are	be	VBP
cord-353633-a4pu6rlu	457	35	strongly	strongly	RB
cord-353633-a4pu6rlu	457	36	associated	associate	VBN
cord-353633-a4pu6rlu	457	37	with	with	IN
cord-353633-a4pu6rlu	457	38	severity	severity	NN
cord-353633-a4pu6rlu	457	39	of	of	IN
cord-353633-a4pu6rlu	457	40	non	non	JJ
cord-353633-a4pu6rlu	457	41	-	-	JJ
cord-353633-a4pu6rlu	457	42	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	457	43	fatty	fatty	JJ
cord-353633-a4pu6rlu	457	44	liver	liver	NN
cord-353633-a4pu6rlu	457	45	disease	disease	NN
cord-353633-a4pu6rlu	457	46	in	in	IN
cord-353633-a4pu6rlu	457	47	Japanese	japanese	JJ
cord-353633-a4pu6rlu	457	48	Combined	combined	JJ
cord-353633-a4pu6rlu	457	49	effects	effect	NNS
cord-353633-a4pu6rlu	457	50	of	of	IN
cord-353633-a4pu6rlu	457	51	the	the	DT
cord-353633-a4pu6rlu	457	52	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	457	53	rs738409	rs738409	NN
cord-353633-a4pu6rlu	457	54	,	,	,
cord-353633-a4pu6rlu	457	55	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	457	56	rs58542926	rs58542926	NNP
cord-353633-a4pu6rlu	457	57	,	,	,
cord-353633-a4pu6rlu	457	58	and	and	CC
cord-353633-a4pu6rlu	457	59	MBOAT7	MBOAT7	NNP
cord-353633-a4pu6rlu	457	60	rs641738	rs641738	NN
cord-353633-a4pu6rlu	457	61	variants	variant	NNS
cord-353633-a4pu6rlu	457	62	on	on	IN
cord-353633-a4pu6rlu	457	63	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	457	64	severity	severity	NN
cord-353633-a4pu6rlu	457	65	:	:	:
cord-353633-a4pu6rlu	458	1	a	a	DT
cord-353633-a4pu6rlu	458	2	multicenter	multicenter	JJ
cord-353633-a4pu6rlu	458	3	biopsy	biopsy	NN
cord-353633-a4pu6rlu	458	4	-	-	HYPH
cord-353633-a4pu6rlu	458	5	based	base	VBN
cord-353633-a4pu6rlu	458	6	study	study	NN
cord-353633-a4pu6rlu	458	7	Adiposity	Adiposity	NNP
cord-353633-a4pu6rlu	458	8	amplifies	amplify	VBZ
cord-353633-a4pu6rlu	458	9	the	the	DT
cord-353633-a4pu6rlu	458	10	genetic	genetic	JJ
cord-353633-a4pu6rlu	458	11	risk	risk	NN
cord-353633-a4pu6rlu	458	12	of	of	IN
cord-353633-a4pu6rlu	458	13	fatty	fatty	JJ
cord-353633-a4pu6rlu	458	14	liver	liver	NN
cord-353633-a4pu6rlu	458	15	disease	disease	NN
cord-353633-a4pu6rlu	458	16	conferred	confer	VBN
cord-353633-a4pu6rlu	458	17	by	by	IN
cord-353633-a4pu6rlu	458	18	multiple	multiple	JJ
cord-353633-a4pu6rlu	458	19	loci	locus	NNS
cord-353633-a4pu6rlu	458	20	Genetic	genetic	JJ
cord-353633-a4pu6rlu	458	21	determinants	determinant	NNS
cord-353633-a4pu6rlu	458	22	of	of	IN
cord-353633-a4pu6rlu	458	23	steatosis	steatosis	NN
cord-353633-a4pu6rlu	458	24	and	and	CC
cord-353633-a4pu6rlu	458	25	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	458	26	progression	progression	NN
cord-353633-a4pu6rlu	458	27	in	in	IN
cord-353633-a4pu6rlu	458	28	paediatric	paediatric	JJ
cord-353633-a4pu6rlu	458	29	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	458	30	fatty	fatty	JJ
cord-353633-a4pu6rlu	458	31	liver	liver	NN
cord-353633-a4pu6rlu	458	32	disease	disease	NN
cord-353633-a4pu6rlu	458	33	Carriage	carriage	NN
cord-353633-a4pu6rlu	458	34	of	of	IN
cord-353633-a4pu6rlu	458	35	the	the	DT
cord-353633-a4pu6rlu	458	36	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	459	1	rs738409	rs738409	NNP
cord-353633-a4pu6rlu	459	2	C	C	NNP
cord-353633-a4pu6rlu	460	1	>	>	XX
cord-353633-a4pu6rlu	461	1	G	g	NN
cord-353633-a4pu6rlu	461	2	polymorphism	polymorphism	NN
cord-353633-a4pu6rlu	461	3	confers	confer	VBZ
cord-353633-a4pu6rlu	461	4	an	an	DT
cord-353633-a4pu6rlu	461	5	increased	increase	VBN
cord-353633-a4pu6rlu	461	6	risk	risk	NN
cord-353633-a4pu6rlu	461	7	of	of	IN
cord-353633-a4pu6rlu	461	8	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	461	9	fatty	fatty	JJ
cord-353633-a4pu6rlu	461	10	liver	liver	NN
cord-353633-a4pu6rlu	461	11	disease	disease	NN
cord-353633-a4pu6rlu	461	12	associated	associate	VBN
cord-353633-a4pu6rlu	461	13	hepatocellular	hepatocellular	NNP
cord-353633-a4pu6rlu	461	14	carcinoma	carcinoma	NNP
cord-353633-a4pu6rlu	461	15	Association	Association	NNP
cord-353633-a4pu6rlu	461	16	Between	between	IN
cord-353633-a4pu6rlu	461	17	PNPLA3	PNPLA3	NNP
cord-353633-a4pu6rlu	462	1	rs738409	rs738409	NNP
cord-353633-a4pu6rlu	462	2	C	C	NNP
cord-353633-a4pu6rlu	463	1	>	>	XX
cord-353633-a4pu6rlu	464	1	G	g	NN
cord-353633-a4pu6rlu	464	2	Variant	variant	NN
cord-353633-a4pu6rlu	464	3	and	and	CC
cord-353633-a4pu6rlu	464	4	Liver	liver	NN
cord-353633-a4pu6rlu	464	5	-	-	HYPH
cord-353633-a4pu6rlu	464	6	Related	relate	VBN
cord-353633-a4pu6rlu	464	7	Outcomes	Outcomes	NNPS
cord-353633-a4pu6rlu	464	8	in	in	IN
cord-353633-a4pu6rlu	464	9	Patients	patient	NNS
cord-353633-a4pu6rlu	464	10	With	with	IN
cord-353633-a4pu6rlu	464	11	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	464	12	Fatty	fatty	JJ
cord-353633-a4pu6rlu	464	13	Liver	Liver	NNP
cord-353633-a4pu6rlu	464	14	Disease	Disease	NNP
cord-353633-a4pu6rlu	464	15	Exome	Exome	NNP
cord-353633-a4pu6rlu	464	16	-	-	HYPH
cord-353633-a4pu6rlu	464	17	wide	wide	JJ
cord-353633-a4pu6rlu	464	18	association	association	NN
cord-353633-a4pu6rlu	464	19	study	study	NN
cord-353633-a4pu6rlu	464	20	identifies	identify	VBZ
cord-353633-a4pu6rlu	464	21	a	a	DT
cord-353633-a4pu6rlu	464	22	TM6SF2	tm6sf2	JJ
cord-353633-a4pu6rlu	464	23	variant	variant	NN
cord-353633-a4pu6rlu	464	24	that	that	WDT
cord-353633-a4pu6rlu	464	25	confers	confer	VBZ
cord-353633-a4pu6rlu	464	26	susceptibility	susceptibility	NN
cord-353633-a4pu6rlu	464	27	to	to	IN
cord-353633-a4pu6rlu	464	28	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	464	29	fatty	fatty	JJ
cord-353633-a4pu6rlu	464	30	liver	liver	NN
cord-353633-a4pu6rlu	464	31	disease	disease	NN
cord-353633-a4pu6rlu	464	32	Impaired	impair	VBD
cord-353633-a4pu6rlu	464	33	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	464	34	lipid	lipid	NN
cord-353633-a4pu6rlu	464	35	synthesis	synthesis	NN
cord-353633-a4pu6rlu	464	36	from	from	IN
cord-353633-a4pu6rlu	464	37	polyunsaturated	polyunsaturated	JJ
cord-353633-a4pu6rlu	464	38	fatty	fatty	JJ
cord-353633-a4pu6rlu	464	39	acids	acid	NNS
cord-353633-a4pu6rlu	464	40	in	in	IN
cord-353633-a4pu6rlu	464	41	TM6SF2	tm6sf2	JJ
cord-353633-a4pu6rlu	464	42	E167	e167	NN
cord-353633-a4pu6rlu	464	43	K	k	NN
cord-353633-a4pu6rlu	464	44	variant	variant	NN
cord-353633-a4pu6rlu	464	45	carriers	carrier	NNS
cord-353633-a4pu6rlu	464	46	with	with	IN
cord-353633-a4pu6rlu	465	1	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	465	2	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	465	3	rs58542926	rs58542926	NNP
cord-353633-a4pu6rlu	465	4	influences	influence	VBZ
cord-353633-a4pu6rlu	465	5	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	465	6	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	465	7	progression	progression	NN
cord-353633-a4pu6rlu	465	8	in	in	IN
cord-353633-a4pu6rlu	465	9	patients	patient	NNS
cord-353633-a4pu6rlu	465	10	with	with	IN
cord-353633-a4pu6rlu	465	11	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	465	12	fatty	fatty	JJ
cord-353633-a4pu6rlu	465	13	liver	liver	NN
cord-353633-a4pu6rlu	465	14	disease	disease	NN
cord-353633-a4pu6rlu	465	15	Genetic	genetic	JJ
cord-353633-a4pu6rlu	465	16	variation	variation	NN
cord-353633-a4pu6rlu	465	17	in	in	IN
cord-353633-a4pu6rlu	465	18	transmembrane	transmembrane	NNP
cord-353633-a4pu6rlu	465	19	6	6	CD
cord-353633-a4pu6rlu	465	20	superfamily	superfamily	NN
cord-353633-a4pu6rlu	465	21	member	member	NN
cord-353633-a4pu6rlu	465	22	2	2	CD
cord-353633-a4pu6rlu	465	23	and	and	CC
cord-353633-a4pu6rlu	465	24	the	the	DT
cord-353633-a4pu6rlu	465	25	risk	risk	NN
cord-353633-a4pu6rlu	465	26	of	of	IN
cord-353633-a4pu6rlu	465	27	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	465	28	fatty	fatty	JJ
cord-353633-a4pu6rlu	465	29	liver	liver	NN
cord-353633-a4pu6rlu	465	30	disease	disease	NN
cord-353633-a4pu6rlu	465	31	and	and	CC
cord-353633-a4pu6rlu	465	32	histological	histological	JJ
cord-353633-a4pu6rlu	465	33	disease	disease	NN
cord-353633-a4pu6rlu	465	34	severity	severity	NN
cord-353633-a4pu6rlu	465	35	MBOAT7	mboat7	NN
cord-353633-a4pu6rlu	465	36	rs641738	rs641738	NN
cord-353633-a4pu6rlu	465	37	variant	variant	NN
cord-353633-a4pu6rlu	465	38	and	and	CC
cord-353633-a4pu6rlu	465	39	hepatocellular	hepatocellular	JJ
cord-353633-a4pu6rlu	465	40	carcinoma	carcinoma	NN
cord-353633-a4pu6rlu	465	41	in	in	IN
cord-353633-a4pu6rlu	465	42	non	non	JJ
cord-353633-a4pu6rlu	465	43	-	-	JJ
cord-353633-a4pu6rlu	465	44	cirrhotic	cirrhotic	JJ
cord-353633-a4pu6rlu	465	45	individuals	individual	NNS
cord-353633-a4pu6rlu	466	1	An	an	DT
cord-353633-a4pu6rlu	466	2	intronic	intronic	JJ
cord-353633-a4pu6rlu	466	3	variant	variant	NN
cord-353633-a4pu6rlu	466	4	in	in	IN
cord-353633-a4pu6rlu	466	5	the	the	DT
cord-353633-a4pu6rlu	466	6	GCKR	GCKR	NNP
cord-353633-a4pu6rlu	466	7	gene	gene	NN
cord-353633-a4pu6rlu	466	8	is	be	VBZ
cord-353633-a4pu6rlu	466	9	associated	associate	VBN
cord-353633-a4pu6rlu	466	10	with	with	IN
cord-353633-a4pu6rlu	466	11	multiple	multiple	JJ
cord-353633-a4pu6rlu	466	12	lipids	lipid	NNS
cord-353633-a4pu6rlu	466	13	Common	common	JJ
cord-353633-a4pu6rlu	466	14	variant	variant	NN
cord-353633-a4pu6rlu	466	15	in	in	IN
cord-353633-a4pu6rlu	466	16	the	the	DT
cord-353633-a4pu6rlu	466	17	glucokinase	glucokinase	NN
cord-353633-a4pu6rlu	466	18	regulatory	regulatory	JJ
cord-353633-a4pu6rlu	466	19	gene	gene	NN
cord-353633-a4pu6rlu	466	20	rs780094	rs780094	NN
cord-353633-a4pu6rlu	466	21	and	and	CC
cord-353633-a4pu6rlu	466	22	risk	risk	NN
cord-353633-a4pu6rlu	466	23	of	of	IN
cord-353633-a4pu6rlu	466	24	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	466	25	fatty	fatty	JJ
cord-353633-a4pu6rlu	466	26	liver	liver	NN
cord-353633-a4pu6rlu	466	27	disease	disease	NN
cord-353633-a4pu6rlu	466	28	:	:	:
cord-353633-a4pu6rlu	466	29	a	a	DT
cord-353633-a4pu6rlu	466	30	metaanalysis	metaanalysis	NN
cord-353633-a4pu6rlu	466	31	Update	update	NN
cord-353633-a4pu6rlu	466	32	on	on	IN
cord-353633-a4pu6rlu	466	33	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	466	34	genetics	genetics	NN
cord-353633-a4pu6rlu	466	35	:	:	:
cord-353633-a4pu6rlu	467	1	From	from	IN
cord-353633-a4pu6rlu	467	2	new	new	JJ
cord-353633-a4pu6rlu	467	3	variants	variant	NNS
cord-353633-a4pu6rlu	467	4	to	to	IN
cord-353633-a4pu6rlu	467	5	the	the	DT
cord-353633-a4pu6rlu	467	6	clinic	clinic	NN
cord-353633-a4pu6rlu	467	7	A	a	DT
cord-353633-a4pu6rlu	467	8	Pathophysiologic	Pathophysiologic	NNP
cord-353633-a4pu6rlu	467	9	Approach	Approach	NNP
cord-353633-a4pu6rlu	467	10	Combining	Combining	NNP
cord-353633-a4pu6rlu	467	11	Genetics	Genetics	NNP
cord-353633-a4pu6rlu	467	12	and	and	CC
cord-353633-a4pu6rlu	467	13	Insulin	Insulin	NNP
cord-353633-a4pu6rlu	467	14	Resistance	Resistance	NNP
cord-353633-a4pu6rlu	467	15	to	to	TO
cord-353633-a4pu6rlu	467	16	Predict	predict	VB
cord-353633-a4pu6rlu	467	17	the	the	DT
cord-353633-a4pu6rlu	467	18	Severity	severity	NN
cord-353633-a4pu6rlu	467	19	of	of	IN
cord-353633-a4pu6rlu	467	20	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	467	21	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	467	22	Liver	Liver	NNP
cord-353633-a4pu6rlu	467	23	Disease	Disease	NNP
cord-353633-a4pu6rlu	468	1	A	a	DT
cord-353633-a4pu6rlu	469	1	Protein	protein	NN
cord-353633-a4pu6rlu	469	2	-	-	HYPH
cord-353633-a4pu6rlu	469	3	Truncating	truncate	VBG
cord-353633-a4pu6rlu	469	4	HSD17B13	HSD17B13	NNP
cord-353633-a4pu6rlu	469	5	Variant	Variant	NNP
cord-353633-a4pu6rlu	469	6	and	and	CC
cord-353633-a4pu6rlu	469	7	Protection	Protection	NNP
cord-353633-a4pu6rlu	469	8	from	from	IN
cord-353633-a4pu6rlu	469	9	Chronic	Chronic	NNP
cord-353633-a4pu6rlu	469	10	Liver	Liver	NNP
cord-353633-a4pu6rlu	469	11	Disease	Disease	NNP
cord-353633-a4pu6rlu	469	12	Genome	Genome	NNP
cord-353633-a4pu6rlu	469	13	-	-	HYPH
cord-353633-a4pu6rlu	469	14	wide	wide	JJ
cord-353633-a4pu6rlu	469	15	and	and	CC
cord-353633-a4pu6rlu	469	16	Mendelian	mendelian	JJ
cord-353633-a4pu6rlu	469	17	randomisation	randomisation	NN
cord-353633-a4pu6rlu	469	18	studies	study	NNS
cord-353633-a4pu6rlu	469	19	of	of	IN
cord-353633-a4pu6rlu	469	20	liver	liver	NN
cord-353633-a4pu6rlu	469	21	MRI	MRI	NNP
cord-353633-a4pu6rlu	469	22	yield	yield	NN
cord-353633-a4pu6rlu	469	23	insights	insight	NNS
cord-353633-a4pu6rlu	469	24	into	into	IN
cord-353633-a4pu6rlu	469	25	the	the	DT
cord-353633-a4pu6rlu	469	26	pathogenesis	pathogenesis	NN
cord-353633-a4pu6rlu	469	27	of	of	IN
cord-353633-a4pu6rlu	469	28	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	469	29	Genome	Genome	NNP
cord-353633-a4pu6rlu	469	30	-	-	HYPH
cord-353633-a4pu6rlu	469	31	wide	wide	NNP
cord-353633-a4pu6rlu	469	32	association	association	NN
cord-353633-a4pu6rlu	469	33	study	study	NN
cord-353633-a4pu6rlu	469	34	of	of	IN
cord-353633-a4pu6rlu	469	35	non	non	JJ
cord-353633-a4pu6rlu	469	36	-	-	JJ
cord-353633-a4pu6rlu	469	37	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	469	38	fatty	fatty	JJ
cord-353633-a4pu6rlu	469	39	liver	liver	NN
cord-353633-a4pu6rlu	469	40	and	and	CC
cord-353633-a4pu6rlu	469	41	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	469	42	in	in	IN
cord-353633-a4pu6rlu	469	43	a	a	DT
cord-353633-a4pu6rlu	469	44	histologically	histologically	RB
cord-353633-a4pu6rlu	469	45	-	-	HYPH
cord-353633-a4pu6rlu	469	46	characterised	characterise	VBN
cord-353633-a4pu6rlu	469	47	cohort	cohort	NN
cord-353633-a4pu6rlu	469	48	Prediction	prediction	NN
cord-353633-a4pu6rlu	469	49	of	of	IN
cord-353633-a4pu6rlu	469	50	non	non	JJ
cord-353633-a4pu6rlu	469	51	-	-	JJ
cord-353633-a4pu6rlu	469	52	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	469	53	fatty	fatty	JJ
cord-353633-a4pu6rlu	469	54	liver	liver	NN
cord-353633-a4pu6rlu	469	55	disease	disease	NN
cord-353633-a4pu6rlu	469	56	and	and	CC
cord-353633-a4pu6rlu	469	57	liver	liver	NN
cord-353633-a4pu6rlu	469	58	fat	fat	NN
cord-353633-a4pu6rlu	469	59	using	use	VBG
cord-353633-a4pu6rlu	469	60	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	469	61	and	and	CC
cord-353633-a4pu6rlu	469	62	genetic	genetic	JJ
cord-353633-a4pu6rlu	469	63	factors	factor	NNS
cord-353633-a4pu6rlu	469	64	Noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	469	65	Detection	Detection	NNP
cord-353633-a4pu6rlu	469	66	of	of	IN
cord-353633-a4pu6rlu	469	67	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	469	68	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	469	69	Using	use	VBG
cord-353633-a4pu6rlu	469	70	Clinical	Clinical	NNP
cord-353633-a4pu6rlu	469	71	Markers	Markers	NNPS
cord-353633-a4pu6rlu	469	72	and	and	CC
cord-353633-a4pu6rlu	469	73	Circulating	circulate	VBG
cord-353633-a4pu6rlu	469	74	Levels	level	NNS
cord-353633-a4pu6rlu	469	75	of	of	IN
cord-353633-a4pu6rlu	469	76	Lipids	lipid	NNS
cord-353633-a4pu6rlu	469	77	and	and	CC
cord-353633-a4pu6rlu	469	78	Metabolites	Metabolites	NNPS
cord-353633-a4pu6rlu	469	79	Development	Development	NNP
cord-353633-a4pu6rlu	469	80	and	and	CC
cord-353633-a4pu6rlu	469	81	Validation	Validation	NNP
cord-353633-a4pu6rlu	469	82	of	of	IN
cord-353633-a4pu6rlu	469	83	a	a	DT
cord-353633-a4pu6rlu	469	84	Scoring	Scoring	NNP
cord-353633-a4pu6rlu	469	85	System	system	NN
cord-353633-a4pu6rlu	469	86	,	,	,
cord-353633-a4pu6rlu	470	1	Based	base	VBN
cord-353633-a4pu6rlu	470	2	on	on	IN
cord-353633-a4pu6rlu	470	3	Genetic	Genetic	NNP
cord-353633-a4pu6rlu	470	4	and	and	CC
cord-353633-a4pu6rlu	470	5	Clinical	Clinical	NNP
cord-353633-a4pu6rlu	470	6	Factors	Factors	NNPS
cord-353633-a4pu6rlu	470	7	,	,	,
cord-353633-a4pu6rlu	470	8	to	to	TO
cord-353633-a4pu6rlu	470	9	Determine	determine	VB
cord-353633-a4pu6rlu	470	10	Risk	risk	NN
cord-353633-a4pu6rlu	470	11	of	of	IN
cord-353633-a4pu6rlu	470	12	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	470	13	in	in	IN
cord-353633-a4pu6rlu	470	14	Asian	Asian	NNP
cord-353633-a4pu6rlu	470	15	Patients	Patients	NNPS
cord-353633-a4pu6rlu	470	16	with	with	IN
cord-353633-a4pu6rlu	470	17	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	470	18	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	470	19	Liver	Liver	NNP
cord-353633-a4pu6rlu	470	20	Disease	Disease	NNP
cord-353633-a4pu6rlu	470	21	Combined	Combined	NNP
cord-353633-a4pu6rlu	470	22	Effect	Effect	NNP
cord-353633-a4pu6rlu	470	23	of	of	IN
cord-353633-a4pu6rlu	470	24	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	470	25	,	,	,
cord-353633-a4pu6rlu	470	26	TM6SF2	TM6SF2	NNP
cord-353633-a4pu6rlu	470	27	,	,	,
cord-353633-a4pu6rlu	470	28	and	and	CC
cord-353633-a4pu6rlu	470	29	HSD17B13	HSD17B13	NNP
cord-353633-a4pu6rlu	470	30	Variants	Variants	NNPS
cord-353633-a4pu6rlu	470	31	on	on	IN
cord-353633-a4pu6rlu	470	32	Risk	Risk	NNP
cord-353633-a4pu6rlu	470	33	of	of	IN
cord-353633-a4pu6rlu	470	34	Cirrhosis	Cirrhosis	NNP
cord-353633-a4pu6rlu	470	35	and	and	CC
cord-353633-a4pu6rlu	470	36	Hepatocellular	Hepatocellular	NNP
cord-353633-a4pu6rlu	470	37	Carcinoma	Carcinoma	NNP
cord-353633-a4pu6rlu	470	38	in	in	IN
cord-353633-a4pu6rlu	470	39	the	the	DT
cord-353633-a4pu6rlu	470	40	General	General	NNP
cord-353633-a4pu6rlu	470	41	Population	Population	NNP
cord-353633-a4pu6rlu	471	1	The	the	DT
cord-353633-a4pu6rlu	471	2	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	471	3	and	and	CC
cord-353633-a4pu6rlu	471	4	management	management	NN
cord-353633-a4pu6rlu	471	5	of	of	IN
cord-353633-a4pu6rlu	471	6	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	471	7	fatty	fatty	JJ
cord-353633-a4pu6rlu	471	8	liver	liver	NN
cord-353633-a4pu6rlu	471	9	disease	disease	NN
cord-353633-a4pu6rlu	471	10	:	:	:
cord-353633-a4pu6rlu	472	1	Practice	practice	NN
cord-353633-a4pu6rlu	472	2	guidance	guidance	NN
cord-353633-a4pu6rlu	472	3	from	from	IN
cord-353633-a4pu6rlu	472	4	the	the	DT
cord-353633-a4pu6rlu	472	5	American	American	NNP
cord-353633-a4pu6rlu	472	6	Association	Association	NNP
cord-353633-a4pu6rlu	472	7	for	for	IN
cord-353633-a4pu6rlu	472	8	the	the	DT
cord-353633-a4pu6rlu	472	9	Study	Study	NNP
cord-353633-a4pu6rlu	472	10	of	of	IN
cord-353633-a4pu6rlu	472	11	Liver	Liver	NNP
cord-353633-a4pu6rlu	472	12	Diseases	Diseases	NNPS
cord-353633-a4pu6rlu	472	13	Accumulation	Accumulation	NNP
cord-353633-a4pu6rlu	472	14	of	of	IN
cord-353633-a4pu6rlu	472	15	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	472	16	on	on	IN
cord-353633-a4pu6rlu	472	17	lipid	lipid	NN
cord-353633-a4pu6rlu	472	18	droplets	droplet	NNS
cord-353633-a4pu6rlu	472	19	is	be	VBZ
cord-353633-a4pu6rlu	472	20	the	the	DT
cord-353633-a4pu6rlu	472	21	basis	basis	NN
cord-353633-a4pu6rlu	472	22	of	of	IN
cord-353633-a4pu6rlu	472	23	associated	associated	JJ
cord-353633-a4pu6rlu	472	24	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	472	25	steatosis	steatosis	NN
cord-353633-a4pu6rlu	472	26	Pnpla3	Pnpla3	NNP
cord-353633-a4pu6rlu	472	27	silencing	silence	VBG
cord-353633-a4pu6rlu	472	28	with	with	IN
cord-353633-a4pu6rlu	472	29	antisense	antisense	NN
cord-353633-a4pu6rlu	472	30	oligonucleotides	oligonucleotide	NNS
cord-353633-a4pu6rlu	472	31	ameliorates	ameliorate	VBZ
cord-353633-a4pu6rlu	472	32	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	472	33	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	472	34	and	and	CC
cord-353633-a4pu6rlu	472	35	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	472	36	in	in	IN
cord-353633-a4pu6rlu	472	37	Pnpla3	Pnpla3	NNP
cord-353633-a4pu6rlu	472	38	I148	I148	NNP
cord-353633-a4pu6rlu	472	39	M	M	NNP
cord-353633-a4pu6rlu	472	40	knock	knock	VB
cord-353633-a4pu6rlu	472	41	-	-	HYPH
cord-353633-a4pu6rlu	472	42	in	in	RP
cord-353633-a4pu6rlu	472	43	mice	mouse	NNS
cord-353633-a4pu6rlu	472	44	Phenome	Phenome	NNP
cord-353633-a4pu6rlu	472	45	-	-	HYPH
cord-353633-a4pu6rlu	472	46	wide	wide	JJ
cord-353633-a4pu6rlu	472	47	association	association	NN
cord-353633-a4pu6rlu	472	48	studies	study	NNS
cord-353633-a4pu6rlu	472	49	across	across	IN
cord-353633-a4pu6rlu	472	50	large	large	JJ
cord-353633-a4pu6rlu	472	51	population	population	NN
cord-353633-a4pu6rlu	472	52	cohorts	cohort	NNS
cord-353633-a4pu6rlu	472	53	support	support	VBP
cord-353633-a4pu6rlu	472	54	drug	drug	NN
cord-353633-a4pu6rlu	472	55	target	target	NN
cord-353633-a4pu6rlu	472	56	validation	validation	NN
cord-353633-a4pu6rlu	473	1	The	the	DT
cord-353633-a4pu6rlu	473	2	dual	dual	JJ
cord-353633-a4pu6rlu	473	3	and	and	CC
cord-353633-a4pu6rlu	473	4	opposite	opposite	JJ
cord-353633-a4pu6rlu	473	5	role	role	NN
cord-353633-a4pu6rlu	473	6	of	of	IN
cord-353633-a4pu6rlu	473	7	the	the	DT
cord-353633-a4pu6rlu	473	8	TM6SF2-rs58542926	tm6sf2-rs58542926	JJ
cord-353633-a4pu6rlu	473	9	variant	variant	NN
cord-353633-a4pu6rlu	473	10	in	in	IN
cord-353633-a4pu6rlu	473	11	protecting	protect	VBG
cord-353633-a4pu6rlu	473	12	against	against	IN
cord-353633-a4pu6rlu	473	13	cardiovascular	cardiovascular	JJ
cord-353633-a4pu6rlu	473	14	disease	disease	NN
cord-353633-a4pu6rlu	473	15	and	and	CC
cord-353633-a4pu6rlu	473	16	conferring	confer	VBG
cord-353633-a4pu6rlu	473	17	risk	risk	NN
cord-353633-a4pu6rlu	473	18	for	for	IN
cord-353633-a4pu6rlu	473	19	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	473	20	fatty	fatty	JJ
cord-353633-a4pu6rlu	473	21	liver	liver	NN
cord-353633-a4pu6rlu	473	22	:	:	:
cord-353633-a4pu6rlu	473	23	A	a	DT
cord-353633-a4pu6rlu	473	24	meta	meta	JJ
cord-353633-a4pu6rlu	473	25	-	-	HYPH
cord-353633-a4pu6rlu	473	26	analysis	analysis	NN
cord-353633-a4pu6rlu	473	27	Leveraging	Leveraging	NNP
cord-353633-a4pu6rlu	473	28	Human	Human	NNP
cord-353633-a4pu6rlu	473	29	Genetics	Genetics	NNPS
cord-353633-a4pu6rlu	473	30	to	to	TO
cord-353633-a4pu6rlu	473	31	Identify	identify	VB
cord-353633-a4pu6rlu	473	32	Potential	potential	JJ
cord-353633-a4pu6rlu	473	33	New	New	NNP
cord-353633-a4pu6rlu	473	34	Treatments	treatment	NNS
cord-353633-a4pu6rlu	473	35	for	for	IN
cord-353633-a4pu6rlu	473	36	Fatty	fatty	JJ
cord-353633-a4pu6rlu	473	37	Liver	liver	NN
cord-353633-a4pu6rlu	473	38	Disease	Disease	NNP
cord-353633-a4pu6rlu	474	1	Attenuated	attenuated	JJ
cord-353633-a4pu6rlu	474	2	effect	effect	NN
cord-353633-a4pu6rlu	474	3	of	of	IN
cord-353633-a4pu6rlu	474	4	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	474	5	on	on	IN
cord-353633-a4pu6rlu	474	6	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	474	7	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	474	8	by	by	IN
cord-353633-a4pu6rlu	474	9	HSD17B13	hsd17b13	RB
cord-353633-a4pu6rlu	474	10	in	in	IN
cord-353633-a4pu6rlu	474	11	Japanese	japanese	JJ
cord-353633-a4pu6rlu	474	12	patients	patient	NNS
cord-353633-a4pu6rlu	474	13	with	with	IN
cord-353633-a4pu6rlu	474	14	non	non	JJ
cord-353633-a4pu6rlu	474	15	-	-	JJ
cord-353633-a4pu6rlu	474	16	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	474	17	fatty	fatty	JJ
cord-353633-a4pu6rlu	474	18	liver	liver	NN
cord-353633-a4pu6rlu	474	19	disease	disease	NN
cord-353633-a4pu6rlu	474	20	Relationship	relationship	NN
cord-353633-a4pu6rlu	474	21	between	between	IN
cord-353633-a4pu6rlu	474	22	methylome	methylome	NNP
cord-353633-a4pu6rlu	474	23	and	and	CC
cord-353633-a4pu6rlu	474	24	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	474	25	in	in	IN
cord-353633-a4pu6rlu	474	26	patients	patient	NNS
cord-353633-a4pu6rlu	474	27	with	with	IN
cord-353633-a4pu6rlu	474	28	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	474	29	fatty	fatty	JJ
cord-353633-a4pu6rlu	474	30	liver	liver	NN
cord-353633-a4pu6rlu	474	31	disease	disease	NN
cord-353633-a4pu6rlu	474	32	DNA	dna	NN
cord-353633-a4pu6rlu	474	33	methylation	methylation	NN
cord-353633-a4pu6rlu	474	34	analysis	analysis	NN
cord-353633-a4pu6rlu	474	35	in	in	IN
cord-353633-a4pu6rlu	474	36	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	474	37	fatty	fatty	JJ
cord-353633-a4pu6rlu	474	38	liver	liver	NN
cord-353633-a4pu6rlu	474	39	disease	disease	NN
cord-353633-a4pu6rlu	474	40	suggests	suggest	VBZ
cord-353633-a4pu6rlu	474	41	distinct	distinct	JJ
cord-353633-a4pu6rlu	474	42	disease	disease	NN
cord-353633-a4pu6rlu	474	43	-	-	HYPH
cord-353633-a4pu6rlu	474	44	specific	specific	JJ
cord-353633-a4pu6rlu	474	45	and	and	CC
cord-353633-a4pu6rlu	474	46	remodeling	remodeling	NN
cord-353633-a4pu6rlu	474	47	signatures	signature	NNS
cord-353633-a4pu6rlu	474	48	after	after	IN
cord-353633-a4pu6rlu	474	49	bariatric	bariatric	JJ
cord-353633-a4pu6rlu	474	50	surgery	surgery	NN
cord-353633-a4pu6rlu	474	51	Human	human	JJ
cord-353633-a4pu6rlu	474	52	liver	liver	NN
cord-353633-a4pu6rlu	474	53	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	474	54	alterations	alteration	NNS
cord-353633-a4pu6rlu	474	55	in	in	IN
cord-353633-a4pu6rlu	474	56	non	non	JJ
cord-353633-a4pu6rlu	474	57	-	-	JJ
cord-353633-a4pu6rlu	474	58	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	474	59	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	474	60	are	be	VBP
cord-353633-a4pu6rlu	474	61	related	relate	VBN
cord-353633-a4pu6rlu	474	62	to	to	IN
cord-353633-a4pu6rlu	474	63	insulin	insulin	NN
cord-353633-a4pu6rlu	474	64	action	action	NN
cord-353633-a4pu6rlu	474	65	Epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	474	66	modification	modification	NN
cord-353633-a4pu6rlu	474	67	of	of	IN
cord-353633-a4pu6rlu	474	68	liver	liver	NN
cord-353633-a4pu6rlu	474	69	mitochondrial	mitochondrial	NN
cord-353633-a4pu6rlu	474	70	DNA	dna	NN
cord-353633-a4pu6rlu	474	71	is	be	VBZ
cord-353633-a4pu6rlu	474	72	associated	associate	VBN
cord-353633-a4pu6rlu	474	73	with	with	IN
cord-353633-a4pu6rlu	474	74	histological	histological	JJ
cord-353633-a4pu6rlu	474	75	severity	severity	NN
cord-353633-a4pu6rlu	474	76	of	of	IN
cord-353633-a4pu6rlu	474	77	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	474	78	fatty	fatty	JJ
cord-353633-a4pu6rlu	474	79	liver	liver	NN
cord-353633-a4pu6rlu	474	80	disease	disease	NN
cord-353633-a4pu6rlu	474	81	DNA	dna	NN
cord-353633-a4pu6rlu	474	82	methylation	methylation	NN
cord-353633-a4pu6rlu	474	83	signatures	signature	NNS
cord-353633-a4pu6rlu	474	84	reflect	reflect	VBP
cord-353633-a4pu6rlu	474	85	aging	age	VBG
cord-353633-a4pu6rlu	474	86	in	in	IN
cord-353633-a4pu6rlu	474	87	patients	patient	NNS
cord-353633-a4pu6rlu	474	88	with	with	IN
cord-353633-a4pu6rlu	474	89	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	474	90	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	474	91	Targetedbisulfite	Targetedbisulfite	NNP
cord-353633-a4pu6rlu	474	92	sequence	sequence	NN
cord-353633-a4pu6rlu	474	93	analysis	analysis	NN
cord-353633-a4pu6rlu	474	94	of	of	IN
cord-353633-a4pu6rlu	474	95	the	the	DT
cord-353633-a4pu6rlu	474	96	methylation	methylation	NN
cord-353633-a4pu6rlu	474	97	of	of	IN
cord-353633-a4pu6rlu	474	98	CpG	CpG	NNP
cord-353633-a4pu6rlu	474	99	islands	island	NNS
cord-353633-a4pu6rlu	474	100	in	in	IN
cord-353633-a4pu6rlu	474	101	genes	gene	NNS
cord-353633-a4pu6rlu	474	102	encoding	encode	VBG
cord-353633-a4pu6rlu	474	103	PNPLA3	pnpla3	NN
cord-353633-a4pu6rlu	474	104	,	,	,
cord-353633-a4pu6rlu	474	105	SAMM50	samm50	XX
cord-353633-a4pu6rlu	474	106	,	,	,
cord-353633-a4pu6rlu	474	107	and	and	CC
cord-353633-a4pu6rlu	474	108	PARVB	PARVB	NNP
cord-353633-a4pu6rlu	474	109	of	of	IN
cord-353633-a4pu6rlu	474	110	patients	patient	NNS
cord-353633-a4pu6rlu	474	111	with	with	IN
cord-353633-a4pu6rlu	474	112	non	non	JJ
cord-353633-a4pu6rlu	474	113	-	-	JJ
cord-353633-a4pu6rlu	474	114	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	474	115	fatty	fatty	JJ
cord-353633-a4pu6rlu	474	116	liver	liver	NN
cord-353633-a4pu6rlu	474	117	disease	disease	NN
cord-353633-a4pu6rlu	474	118	Identification	identification	NN
cord-353633-a4pu6rlu	474	119	of	of	IN
cord-353633-a4pu6rlu	474	120	the	the	DT
cord-353633-a4pu6rlu	474	121	genomic	genomic	JJ
cord-353633-a4pu6rlu	474	122	region	region	NN
cord-353633-a4pu6rlu	474	123	under	under	IN
cord-353633-a4pu6rlu	474	124	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	474	125	regulation	regulation	NN
cord-353633-a4pu6rlu	474	126	during	during	IN
cord-353633-a4pu6rlu	474	127	non	non	JJ
cord-353633-a4pu6rlu	474	128	-	-	JJ
cord-353633-a4pu6rlu	474	129	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	474	130	fatty	fatty	JJ
cord-353633-a4pu6rlu	474	131	liver	liver	NN
cord-353633-a4pu6rlu	474	132	disease	disease	NN
cord-353633-a4pu6rlu	474	133	progression	progression	NN
cord-353633-a4pu6rlu	474	134	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	474	135	stellate	stellate	JJ
cord-353633-a4pu6rlu	474	136	cell	cell	NN
cord-353633-a4pu6rlu	474	137	transdifferentiation	transdifferentiation	NN
cord-353633-a4pu6rlu	474	138	involves	involve	VBZ
cord-353633-a4pu6rlu	474	139	genome	genome	NN
cord-353633-a4pu6rlu	474	140	-	-	HYPH
cord-353633-a4pu6rlu	474	141	wide	wide	JJ
cord-353633-a4pu6rlu	474	142	remodeling	remodeling	NN
cord-353633-a4pu6rlu	474	143	of	of	IN
cord-353633-a4pu6rlu	474	144	the	the	DT
cord-353633-a4pu6rlu	474	145	DNA	dna	NN
cord-353633-a4pu6rlu	474	146	methylation	methylation	NN
cord-353633-a4pu6rlu	474	147	landscape	landscape	NN
cord-353633-a4pu6rlu	475	1	MeCP2	mecp2	DT
cord-353633-a4pu6rlu	475	2	controls	control	VBZ
cord-353633-a4pu6rlu	475	3	an	an	DT
cord-353633-a4pu6rlu	475	4	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	475	5	pathway	pathway	NN
cord-353633-a4pu6rlu	475	6	that	that	WDT
cord-353633-a4pu6rlu	475	7	promotes	promote	VBZ
cord-353633-a4pu6rlu	475	8	myofibroblast	myofibroblast	JJ
cord-353633-a4pu6rlu	475	9	transdifferentiation	transdifferentiation	NN
cord-353633-a4pu6rlu	475	10	and	and	CC
cord-353633-a4pu6rlu	475	11	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	475	12	Differential	differential	NN
cord-353633-a4pu6rlu	475	13	DNA	dna	NN
cord-353633-a4pu6rlu	475	14	methylation	methylation	NN
cord-353633-a4pu6rlu	475	15	of	of	IN
cord-353633-a4pu6rlu	475	16	genes	gene	NNS
cord-353633-a4pu6rlu	475	17	involved	involve	VBN
cord-353633-a4pu6rlu	475	18	in	in	IN
cord-353633-a4pu6rlu	475	19	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	475	20	progression	progression	NN
cord-353633-a4pu6rlu	475	21	in	in	IN
cord-353633-a4pu6rlu	475	22	non	non	JJ
cord-353633-a4pu6rlu	475	23	-	-	JJ
cord-353633-a4pu6rlu	475	24	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	475	25	fatty	fatty	JJ
cord-353633-a4pu6rlu	475	26	liver	liver	NN
cord-353633-a4pu6rlu	475	27	disease	disease	NN
cord-353633-a4pu6rlu	475	28	and	and	CC
cord-353633-a4pu6rlu	475	29	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	475	30	liver	liver	NN
cord-353633-a4pu6rlu	475	31	disease	disease	NN
cord-353633-a4pu6rlu	475	32	Multigenerational	multigenerational	JJ
cord-353633-a4pu6rlu	475	33	epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	475	34	adaptation	adaptation	NN
cord-353633-a4pu6rlu	475	35	of	of	IN
cord-353633-a4pu6rlu	475	36	the	the	DT
cord-353633-a4pu6rlu	475	37	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	475	38	wound	wound	NN
cord-353633-a4pu6rlu	475	39	-	-	HYPH
cord-353633-a4pu6rlu	475	40	healing	heal	VBG
cord-353633-a4pu6rlu	475	41	response	response	NN
cord-353633-a4pu6rlu	475	42	Epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	475	43	regulation	regulation	NN
cord-353633-a4pu6rlu	475	44	of	of	IN
cord-353633-a4pu6rlu	475	45	insulin	insulin	NN
cord-353633-a4pu6rlu	475	46	resistance	resistance	NN
cord-353633-a4pu6rlu	475	47	in	in	IN
cord-353633-a4pu6rlu	475	48	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	475	49	fatty	fatty	JJ
cord-353633-a4pu6rlu	475	50	liver	liver	NN
cord-353633-a4pu6rlu	475	51	disease	disease	NN
cord-353633-a4pu6rlu	475	52	:	:	:
cord-353633-a4pu6rlu	475	53	impact	impact	NN
cord-353633-a4pu6rlu	475	54	of	of	IN
cord-353633-a4pu6rlu	475	55	liver	liver	NN
cord-353633-a4pu6rlu	475	56	methylation	methylation	NN
cord-353633-a4pu6rlu	475	57	of	of	IN
cord-353633-a4pu6rlu	475	58	the	the	DT
cord-353633-a4pu6rlu	475	59	peroxisome	peroxisome	NN
cord-353633-a4pu6rlu	475	60	proliferator	proliferator	NN
cord-353633-a4pu6rlu	475	61	-	-	HYPH
cord-353633-a4pu6rlu	475	62	activated	activate	VBN
cord-353633-a4pu6rlu	475	63	receptor	receptor	NN
cord-353633-a4pu6rlu	475	64	gamma	gamma	NN
cord-353633-a4pu6rlu	475	65	coactivator	coactivator	NN
cord-353633-a4pu6rlu	475	66	1alpha	1alpha	CD
cord-353633-a4pu6rlu	475	67	promoter	promoter	NN
cord-353633-a4pu6rlu	475	68	Identification	Identification	NNP
cord-353633-a4pu6rlu	475	69	of	of	IN
cord-353633-a4pu6rlu	475	70	differentially	differentially	RB
cord-353633-a4pu6rlu	475	71	methylated	methylate	VBN
cord-353633-a4pu6rlu	475	72	region	region	NN
cord-353633-a4pu6rlu	475	73	(	(	-LRB-
cord-353633-a4pu6rlu	475	74	DMR	DMR	NNP
cord-353633-a4pu6rlu	475	75	)	)	-RRB-
cord-353633-a4pu6rlu	475	76	networks	network	NNS
cord-353633-a4pu6rlu	475	77	associated	associate	VBN
cord-353633-a4pu6rlu	475	78	with	with	IN
cord-353633-a4pu6rlu	475	79	progression	progression	NN
cord-353633-a4pu6rlu	475	80	of	of	IN
cord-353633-a4pu6rlu	475	81	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	475	82	fatty	fatty	JJ
cord-353633-a4pu6rlu	475	83	liver	liver	NN
cord-353633-a4pu6rlu	475	84	disease	disease	NN
cord-353633-a4pu6rlu	475	85	Epigenetics	Epigenetics	NNP
cord-353633-a4pu6rlu	475	86	in	in	IN
cord-353633-a4pu6rlu	475	87	non	non	JJ
cord-353633-a4pu6rlu	475	88	-	-	JJ
cord-353633-a4pu6rlu	475	89	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	475	90	fatty	fatty	JJ
cord-353633-a4pu6rlu	475	91	liver	liver	NN
cord-353633-a4pu6rlu	475	92	disease	disease	NN
cord-353633-a4pu6rlu	475	93	Tannic	tannic	JJ
cord-353633-a4pu6rlu	475	94	acid	acid	NN
cord-353633-a4pu6rlu	475	95	,	,	,
cord-353633-a4pu6rlu	475	96	a	a	DT
cord-353633-a4pu6rlu	475	97	novel	novel	JJ
cord-353633-a4pu6rlu	475	98	histone	histone	NN
cord-353633-a4pu6rlu	475	99	acetyltransferase	acetyltransferase	NN
cord-353633-a4pu6rlu	475	100	inhibitor	inhibitor	NN
cord-353633-a4pu6rlu	475	101	,	,	,
cord-353633-a4pu6rlu	475	102	prevents	prevent	VBZ
cord-353633-a4pu6rlu	475	103	non	non	JJ
cord-353633-a4pu6rlu	475	104	-	-	JJ
cord-353633-a4pu6rlu	475	105	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	475	106	fatty	fatty	JJ
cord-353633-a4pu6rlu	475	107	liver	liver	NN
cord-353633-a4pu6rlu	475	108	disease	disease	NN
cord-353633-a4pu6rlu	475	109	both	both	CC
cord-353633-a4pu6rlu	475	110	in	in	IN
cord-353633-a4pu6rlu	475	111	vivo	vivo	NN
cord-353633-a4pu6rlu	475	112	and	and	CC
cord-353633-a4pu6rlu	475	113	in	in	IN
cord-353633-a4pu6rlu	475	114	vitro	vitro	FW
cord-353633-a4pu6rlu	475	115	model	model	NN
cord-353633-a4pu6rlu	475	116	Elimination	Elimination	NNP
cord-353633-a4pu6rlu	475	117	of	of	IN
cord-353633-a4pu6rlu	475	118	Age	Age	NNP
cord-353633-a4pu6rlu	475	119	-	-	HYPH
cord-353633-a4pu6rlu	475	120	Associated	Associated	NNP
cord-353633-a4pu6rlu	475	121	Hepatic	Hepatic	NNP
cord-353633-a4pu6rlu	475	122	Steatosis	Steatosis	NNP
cord-353633-a4pu6rlu	475	123	and	and	CC
cord-353633-a4pu6rlu	475	124	Correction	correction	NN
cord-353633-a4pu6rlu	475	125	of	of	IN
cord-353633-a4pu6rlu	475	126	Aging	age	VBG
cord-353633-a4pu6rlu	475	127	Phenotype	Phenotype	NNP
cord-353633-a4pu6rlu	475	128	by	by	IN
cord-353633-a4pu6rlu	475	129	Inhibition	Inhibition	NNP
cord-353633-a4pu6rlu	475	130	of	of	IN
cord-353633-a4pu6rlu	475	131	cdk4-C	cdk4-C	NNS
cord-353633-a4pu6rlu	475	132	/	/	SYM
cord-353633-a4pu6rlu	475	133	EBPalpha	EBPalpha	NNP
cord-353633-a4pu6rlu	476	1	-p300	-p300	JJ
cord-353633-a4pu6rlu	477	1	Axis	Axis	NNP
cord-353633-a4pu6rlu	477	2	P300	P300	NNP
cord-353633-a4pu6rlu	478	1	Acetyltransferase	Acetyltransferase	NNP
cord-353633-a4pu6rlu	478	2	Mediates	mediate	VBZ
cord-353633-a4pu6rlu	479	1	Stiffness	stiffness	NN
cord-353633-a4pu6rlu	479	2	-	-	HYPH
cord-353633-a4pu6rlu	479	3	Induced	Induced	NNP
cord-353633-a4pu6rlu	479	4	Activation	Activation	NNP
cord-353633-a4pu6rlu	479	5	of	of	IN
cord-353633-a4pu6rlu	479	6	Hepatic	Hepatic	NNP
cord-353633-a4pu6rlu	479	7	Stellate	Stellate	NNP
cord-353633-a4pu6rlu	479	8	Cells	cell	NNS
cord-353633-a4pu6rlu	479	9	Into	into	IN
cord-353633-a4pu6rlu	479	10	Tumor	tumor	NN
cord-353633-a4pu6rlu	479	11	-	-	HYPH
cord-353633-a4pu6rlu	479	12	Promoting	promote	VBG
cord-353633-a4pu6rlu	479	13	Myofibroblasts	Myofibroblasts	NNP
cord-353633-a4pu6rlu	479	14	SirT1	SirT1	NNP
cord-353633-a4pu6rlu	479	15	gain	gain	NN
cord-353633-a4pu6rlu	479	16	of	of	IN
cord-353633-a4pu6rlu	479	17	function	function	NN
cord-353633-a4pu6rlu	479	18	increases	increase	VBZ
cord-353633-a4pu6rlu	479	19	energy	energy	NN
cord-353633-a4pu6rlu	479	20	efficiency	efficiency	NN
cord-353633-a4pu6rlu	479	21	and	and	CC
cord-353633-a4pu6rlu	479	22	prevents	prevent	VBZ
cord-353633-a4pu6rlu	479	23	diabetes	diabetes	NN
cord-353633-a4pu6rlu	479	24	in	in	IN
cord-353633-a4pu6rlu	479	25	mice	mouse	NNS
cord-353633-a4pu6rlu	480	1	Sirt1	Sirt1	NNP
cord-353633-a4pu6rlu	480	2	protects	protect	VBZ
cord-353633-a4pu6rlu	480	3	against	against	IN
cord-353633-a4pu6rlu	480	4	high	high	JJ
cord-353633-a4pu6rlu	480	5	-	-	HYPH
cord-353633-a4pu6rlu	480	6	fat	fat	NN
cord-353633-a4pu6rlu	480	7	diet	diet	NN
cord-353633-a4pu6rlu	480	8	-	-	HYPH
cord-353633-a4pu6rlu	480	9	induced	induce	VBN
cord-353633-a4pu6rlu	480	10	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	480	11	damage	damage	NN
cord-353633-a4pu6rlu	480	12	Hepatocytespecific	Hepatocytespecific	NNP
cord-353633-a4pu6rlu	480	13	deletion	deletion	NN
cord-353633-a4pu6rlu	480	14	of	of	IN
cord-353633-a4pu6rlu	480	15	SIRT1	sirt1	NN
cord-353633-a4pu6rlu	480	16	alters	alter	VBZ
cord-353633-a4pu6rlu	480	17	fatty	fatty	JJ
cord-353633-a4pu6rlu	480	18	acid	acid	NN
cord-353633-a4pu6rlu	480	19	metabolism	metabolism	NN
cord-353633-a4pu6rlu	480	20	and	and	CC
cord-353633-a4pu6rlu	480	21	results	result	NNS
cord-353633-a4pu6rlu	480	22	in	in	IN
cord-353633-a4pu6rlu	480	23	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	480	24	steatosis	steatosis	NN
cord-353633-a4pu6rlu	480	25	and	and	CC
cord-353633-a4pu6rlu	480	26	inflammation	inflammation	NN
cord-353633-a4pu6rlu	480	27	SIRT3	sirt3	JJ
cord-353633-a4pu6rlu	480	28	deficiency	deficiency	NN
cord-353633-a4pu6rlu	480	29	and	and	CC
cord-353633-a4pu6rlu	481	1	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	481	2	protein	protein	NNP
cord-353633-a4pu6rlu	481	3	hyperacetylation	hyperacetylation	NNP
cord-353633-a4pu6rlu	481	4	accelerate	accelerate	VB
cord-353633-a4pu6rlu	481	5	the	the	DT
cord-353633-a4pu6rlu	481	6	development	development	NN
cord-353633-a4pu6rlu	481	7	of	of	IN
cord-353633-a4pu6rlu	481	8	the	the	DT
cord-353633-a4pu6rlu	481	9	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	481	10	syndrome	syndrome	NN
cord-353633-a4pu6rlu	481	11	Epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	481	12	mechanisms	mechanism	NNS
cord-353633-a4pu6rlu	481	13	underlying	underlie	VBG
cord-353633-a4pu6rlu	481	14	the	the	DT
cord-353633-a4pu6rlu	481	15	link	link	NN
cord-353633-a4pu6rlu	481	16	between	between	IN
cord-353633-a4pu6rlu	481	17	non	non	JJ
cord-353633-a4pu6rlu	481	18	-	-	JJ
cord-353633-a4pu6rlu	481	19	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	481	20	fatty	fatty	JJ
cord-353633-a4pu6rlu	481	21	liver	liver	NN
cord-353633-a4pu6rlu	481	22	diseases	disease	NNS
cord-353633-a4pu6rlu	481	23	and	and	CC
cord-353633-a4pu6rlu	481	24	nutrition	nutrition	NN
cord-353633-a4pu6rlu	481	25	A	a	DT
cord-353633-a4pu6rlu	481	26	circadian	circadian	NN
cord-353633-a4pu6rlu	481	27	rhythm	rhythm	NN
cord-353633-a4pu6rlu	481	28	orchestrated	orchestrate	VBN
cord-353633-a4pu6rlu	481	29	by	by	IN
cord-353633-a4pu6rlu	481	30	histone	histone	NN
cord-353633-a4pu6rlu	481	31	deacetylase	deacetylase	NNP
cord-353633-a4pu6rlu	481	32	3	3	CD
cord-353633-a4pu6rlu	481	33	controls	control	NNS
cord-353633-a4pu6rlu	482	1	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	482	2	lipid	lipid	NN
cord-353633-a4pu6rlu	482	3	metabolism	metabolism	NN
cord-353633-a4pu6rlu	483	1	Plasma	plasma	NN
cord-353633-a4pu6rlu	483	2	DNA	dna	NN
cord-353633-a4pu6rlu	483	3	methylation	methylation	NN
cord-353633-a4pu6rlu	483	4	:	:	:
cord-353633-a4pu6rlu	484	1	a	a	DT
cord-353633-a4pu6rlu	484	2	potential	potential	JJ
cord-353633-a4pu6rlu	484	3	biomarker	biomarker	NN
cord-353633-a4pu6rlu	484	4	for	for	IN
cord-353633-a4pu6rlu	484	5	stratification	stratification	NN
cord-353633-a4pu6rlu	484	6	of	of	IN
cord-353633-a4pu6rlu	484	7	liver	liver	NN
cord-353633-a4pu6rlu	484	8	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	484	9	in	in	IN
cord-353633-a4pu6rlu	484	10	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	484	11	fatty	fatty	JJ
cord-353633-a4pu6rlu	484	12	liver	liver	NN
cord-353633-a4pu6rlu	484	13	disease	disease	NN
cord-353633-a4pu6rlu	484	14	Altered	alter	VBD
cord-353633-a4pu6rlu	484	15	DNA	DNA	NNP
cord-353633-a4pu6rlu	484	16	Methylation	Methylation	NNP
cord-353633-a4pu6rlu	484	17	Sites	Sites	NNPS
cord-353633-a4pu6rlu	484	18	in	in	IN
cord-353633-a4pu6rlu	484	19	Peripheral	Peripheral	NNP
cord-353633-a4pu6rlu	484	20	Blood	Blood	NNP
cord-353633-a4pu6rlu	484	21	Leukocytes	Leukocytes	NNPS
cord-353633-a4pu6rlu	484	22	from	from	IN
cord-353633-a4pu6rlu	484	23	Patients	patient	NNS
cord-353633-a4pu6rlu	484	24	with	with	IN
cord-353633-a4pu6rlu	484	25	Simple	Simple	NNP
cord-353633-a4pu6rlu	484	26	Steatosis	Steatosis	NNP
cord-353633-a4pu6rlu	484	27	and	and	CC
cord-353633-a4pu6rlu	484	28	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	484	29	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	485	1	(	(	-LRB-
cord-353633-a4pu6rlu	485	2	NASH	NASH	NNP
cord-353633-a4pu6rlu	485	3	)	)	-RRB-
cord-353633-a4pu6rlu	486	1	A	a	DT
cord-353633-a4pu6rlu	486	2	Peripheral	Peripheral	NNP
cord-353633-a4pu6rlu	486	3	Blood	blood	NN
cord-353633-a4pu6rlu	486	4	DNA	dna	NN
cord-353633-a4pu6rlu	486	5	Methylation	methylation	NN
cord-353633-a4pu6rlu	486	6	Signature	signature	NN
cord-353633-a4pu6rlu	486	7	of	of	IN
cord-353633-a4pu6rlu	486	8	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	486	9	Fat	Fat	NNP
cord-353633-a4pu6rlu	486	10	Reveals	reveal	VBZ
cord-353633-a4pu6rlu	486	11	a	a	DT
cord-353633-a4pu6rlu	486	12	Potential	potential	JJ
cord-353633-a4pu6rlu	486	13	Causal	Causal	NNP
cord-353633-a4pu6rlu	486	14	Pathway	Pathway	NNP
cord-353633-a4pu6rlu	486	15	for	for	IN
cord-353633-a4pu6rlu	487	1	Nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	487	2	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	487	3	Liver	Liver	NNP
cord-353633-a4pu6rlu	487	4	Disease	Disease	NNP
cord-353633-a4pu6rlu	487	5	Dietary	dietary	JJ
cord-353633-a4pu6rlu	487	6	resveratrol	resveratrol	NN
cord-353633-a4pu6rlu	487	7	alters	alter	VBZ
cord-353633-a4pu6rlu	487	8	lipid	lipid	NN
cord-353633-a4pu6rlu	487	9	metabolismrelated	metabolismrelate	VBN
cord-353633-a4pu6rlu	487	10	gene	gene	NN
cord-353633-a4pu6rlu	487	11	expression	expression	NN
cord-353633-a4pu6rlu	487	12	of	of	IN
cord-353633-a4pu6rlu	487	13	mice	mouse	NNS
cord-353633-a4pu6rlu	487	14	on	on	IN
cord-353633-a4pu6rlu	487	15	an	an	DT
cord-353633-a4pu6rlu	487	16	atherogenic	atherogenic	JJ
cord-353633-a4pu6rlu	487	17	diet	diet	NN
cord-353633-a4pu6rlu	487	18	Effects	effect	NNS
cord-353633-a4pu6rlu	487	19	of	of	IN
cord-353633-a4pu6rlu	487	20	resveratrol	resveratrol	NN
cord-353633-a4pu6rlu	487	21	supplementation	supplementation	NN
cord-353633-a4pu6rlu	487	22	on	on	IN
cord-353633-a4pu6rlu	487	23	liver	liver	NN
cord-353633-a4pu6rlu	487	24	fat	fat	NN
cord-353633-a4pu6rlu	487	25	content	content	NN
cord-353633-a4pu6rlu	487	26	in	in	IN
cord-353633-a4pu6rlu	487	27	overweight	overweight	JJ
cord-353633-a4pu6rlu	487	28	and	and	CC
cord-353633-a4pu6rlu	487	29	insulinresistant	insulinresistant	JJ
cord-353633-a4pu6rlu	487	30	subjects	subject	NNS
cord-353633-a4pu6rlu	487	31	:	:	:
cord-353633-a4pu6rlu	488	1	A	a	DT
cord-353633-a4pu6rlu	488	2	randomized	randomized	JJ
cord-353633-a4pu6rlu	488	3	,	,	,
cord-353633-a4pu6rlu	488	4	double	double	JJ
cord-353633-a4pu6rlu	488	5	-	-	HYPH
cord-353633-a4pu6rlu	488	6	blind	blind	JJ
cord-353633-a4pu6rlu	488	7	,	,	,
cord-353633-a4pu6rlu	488	8	placebo	placebo	NN
cord-353633-a4pu6rlu	488	9	-	-	HYPH
cord-353633-a4pu6rlu	488	10	controlled	control	VBN
cord-353633-a4pu6rlu	488	11	clinical	clinical	JJ
cord-353633-a4pu6rlu	488	12	trial	trial	NN
cord-353633-a4pu6rlu	489	1	No	no	DT
cord-353633-a4pu6rlu	489	2	effect	effect	NN
cord-353633-a4pu6rlu	489	3	of	of	IN
cord-353633-a4pu6rlu	489	4	resveratrol	resveratrol	NN
cord-353633-a4pu6rlu	489	5	on	on	IN
cord-353633-a4pu6rlu	489	6	VLDL	VLDL	NNP
cord-353633-a4pu6rlu	489	7	-	-	HYPH
cord-353633-a4pu6rlu	489	8	TG	tg	NN
cord-353633-a4pu6rlu	489	9	kinetics	kinetic	NNS
cord-353633-a4pu6rlu	489	10	and	and	CC
cord-353633-a4pu6rlu	489	11	insulin	insulin	NN
cord-353633-a4pu6rlu	489	12	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	489	13	in	in	IN
cord-353633-a4pu6rlu	489	14	obese	obese	JJ
cord-353633-a4pu6rlu	489	15	men	man	NNS
cord-353633-a4pu6rlu	489	16	with	with	IN
cord-353633-a4pu6rlu	489	17	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	489	18	fatty	fatty	JJ
cord-353633-a4pu6rlu	489	19	liver	liver	NN
cord-353633-a4pu6rlu	489	20	disease	disease	NN
cord-353633-a4pu6rlu	489	21	Comparison	comparison	NN
cord-353633-a4pu6rlu	489	22	of	of	IN
cord-353633-a4pu6rlu	489	23	Calorie	Calorie	NNP
cord-353633-a4pu6rlu	489	24	-	-	HYPH
cord-353633-a4pu6rlu	489	25	Restricted	Restricted	NNP
cord-353633-a4pu6rlu	489	26	Diet	Diet	NNP
cord-353633-a4pu6rlu	489	27	and	and	CC
cord-353633-a4pu6rlu	489	28	Resveratrol	Resveratrol	NNP
cord-353633-a4pu6rlu	489	29	Supplementation	Supplementation	NNP
cord-353633-a4pu6rlu	489	30	on	on	IN
cord-353633-a4pu6rlu	489	31	Anthropometric	Anthropometric	NNP
cord-353633-a4pu6rlu	489	32	Indices	Indices	NNPS
cord-353633-a4pu6rlu	489	33	,	,	,
cord-353633-a4pu6rlu	489	34	Metabolic	Metabolic	NNP
cord-353633-a4pu6rlu	489	35	Parameters	Parameters	NNPS
cord-353633-a4pu6rlu	489	36	,	,	,
cord-353633-a4pu6rlu	489	37	and	and	CC
cord-353633-a4pu6rlu	489	38	Serum	Serum	NNP
cord-353633-a4pu6rlu	489	39	Sirtuin-1	Sirtuin-1	NNP
cord-353633-a4pu6rlu	489	40	Levels	Levels	NNP
cord-353633-a4pu6rlu	489	41	in	in	IN
cord-353633-a4pu6rlu	489	42	Patients	patient	NNS
cord-353633-a4pu6rlu	489	43	With	with	IN
cord-353633-a4pu6rlu	489	44	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	489	45	Fatty	fatty	JJ
cord-353633-a4pu6rlu	489	46	Liver	Liver	NNP
cord-353633-a4pu6rlu	489	47	Disease	Disease	NNP
cord-353633-a4pu6rlu	489	48	:	:	:
cord-353633-a4pu6rlu	490	1	A	a	DT
cord-353633-a4pu6rlu	490	2	Randomized	Randomized	NNP
cord-353633-a4pu6rlu	490	3	Controlled	Controlled	NNP
cord-353633-a4pu6rlu	490	4	Clinical	Clinical	NNP
cord-353633-a4pu6rlu	490	5	Trial	Trial	NNP
cord-353633-a4pu6rlu	491	1	A	a	DT
cord-353633-a4pu6rlu	491	2	Proof	Proof	NNP
cord-353633-a4pu6rlu	491	3	-	-	HYPH
cord-353633-a4pu6rlu	491	4	of	of	IN
cord-353633-a4pu6rlu	491	5	-	-	HYPH
cord-353633-a4pu6rlu	491	6	Concept	concept	NN
cord-353633-a4pu6rlu	491	7	for	for	IN
cord-353633-a4pu6rlu	491	8	Epigenetic	epigenetic	JJ
cord-353633-a4pu6rlu	491	9	Therapy	therapy	NN
cord-353633-a4pu6rlu	491	10	of	of	IN
cord-353633-a4pu6rlu	491	11	Tissue	Tissue	NNP
cord-353633-a4pu6rlu	491	12	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	491	13	:	:	:
cord-353633-a4pu6rlu	492	1	Inhibition	inhibition	NN
cord-353633-a4pu6rlu	492	2	of	of	IN
cord-353633-a4pu6rlu	492	3	Liver	Liver	NNP
cord-353633-a4pu6rlu	492	4	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	492	5	Progression	Progression	NNP
cord-353633-a4pu6rlu	492	6	by	by	IN
cord-353633-a4pu6rlu	492	7	3-Deazaneplanocin	3-Deazaneplanocin	NNP
cord-353633-a4pu6rlu	492	8	A	a	DT
cord-353633-a4pu6rlu	492	9	Gene	Gene	NNP
cord-353633-a4pu6rlu	492	10	expression	expression	NN
cord-353633-a4pu6rlu	492	11	profile	profile	NN
cord-353633-a4pu6rlu	492	12	-	-	HYPH
cord-353633-a4pu6rlu	492	13	based	base	VBN
cord-353633-a4pu6rlu	492	14	drug	drug	NN
cord-353633-a4pu6rlu	492	15	screen	screen	NN
cord-353633-a4pu6rlu	492	16	identifies	identify	VBZ
cord-353633-a4pu6rlu	492	17	SAHA	SAHA	NNP
cord-353633-a4pu6rlu	492	18	as	as	IN
cord-353633-a4pu6rlu	492	19	a	a	DT
cord-353633-a4pu6rlu	492	20	novel	novel	JJ
cord-353633-a4pu6rlu	492	21	treatment	treatment	NN
cord-353633-a4pu6rlu	492	22	for	for	IN
cord-353633-a4pu6rlu	492	23	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	492	24	Liver	Liver	NNP
cord-353633-a4pu6rlu	492	25	transcriptomics	transcriptomic	NNS
cord-353633-a4pu6rlu	492	26	highlights	highlight	VBZ
cord-353633-a4pu6rlu	492	27	interleukin-32	interleukin-32	NN
cord-353633-a4pu6rlu	492	28	as	as	IN
cord-353633-a4pu6rlu	492	29	novel	novel	JJ
cord-353633-a4pu6rlu	492	30	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	492	31	-	-	HYPH
cord-353633-a4pu6rlu	492	32	related	relate	VBN
cord-353633-a4pu6rlu	492	33	cytokine	cytokine	NN
cord-353633-a4pu6rlu	492	34	and	and	CC
cord-353633-a4pu6rlu	492	35	candidate	candidate	NN
cord-353633-a4pu6rlu	492	36	biomarker	biomarker	NN
cord-353633-a4pu6rlu	492	37	Human	Human	NNP
cord-353633-a4pu6rlu	492	38	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	492	39	gene	gene	NN
cord-353633-a4pu6rlu	492	40	expression	expression	NN
cord-353633-a4pu6rlu	492	41	signature	signature	NN
cord-353633-a4pu6rlu	492	42	of	of	IN
cord-353633-a4pu6rlu	492	43	non	non	JJ
cord-353633-a4pu6rlu	492	44	-	-	JJ
cord-353633-a4pu6rlu	492	45	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	492	46	fatty	fatty	JJ
cord-353633-a4pu6rlu	492	47	liver	liver	NN
cord-353633-a4pu6rlu	492	48	disease	disease	NN
cord-353633-a4pu6rlu	492	49	progression	progression	NN
cord-353633-a4pu6rlu	492	50	,	,	,
cord-353633-a4pu6rlu	493	1	a	a	DT
cord-353633-a4pu6rlu	493	2	meta	meta	JJ
cord-353633-a4pu6rlu	493	3	-	-	HYPH
cord-353633-a4pu6rlu	493	4	analysis	analysis	NN
cord-353633-a4pu6rlu	493	5	Comparison	comparison	NN
cord-353633-a4pu6rlu	493	6	of	of	IN
cord-353633-a4pu6rlu	493	7	Gene	Gene	NNP
cord-353633-a4pu6rlu	493	8	Expression	expression	NN
cord-353633-a4pu6rlu	493	9	Patterns	pattern	NNS
cord-353633-a4pu6rlu	493	10	Between	between	IN
cord-353633-a4pu6rlu	493	11	Mouse	Mouse	NNP
cord-353633-a4pu6rlu	493	12	Models	Models	NNPS
cord-353633-a4pu6rlu	493	13	of	of	IN
cord-353633-a4pu6rlu	493	14	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	493	15	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	493	16	Liver	Liver	NNP
cord-353633-a4pu6rlu	493	17	Disease	Disease	NNP
cord-353633-a4pu6rlu	493	18	and	and	CC
cord-353633-a4pu6rlu	493	19	Liver	liver	NN
cord-353633-a4pu6rlu	493	20	Tissues	tissue	NNS
cord-353633-a4pu6rlu	493	21	From	from	IN
cord-353633-a4pu6rlu	493	22	Patients	Patients	NNP
cord-353633-a4pu6rlu	493	23	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	493	24	gene	gene	NN
cord-353633-a4pu6rlu	493	25	expression	expression	NN
cord-353633-a4pu6rlu	493	26	profiles	profile	NNS
cord-353633-a4pu6rlu	493	27	differentiate	differentiate	VBP
cord-353633-a4pu6rlu	493	28	presymptomatic	presymptomatic	JJ
cord-353633-a4pu6rlu	493	29	patients	patient	NNS
cord-353633-a4pu6rlu	493	30	with	with	IN
cord-353633-a4pu6rlu	493	31	mild	mild	JJ
cord-353633-a4pu6rlu	493	32	versus	versus	IN
cord-353633-a4pu6rlu	493	33	severe	severe	JJ
cord-353633-a4pu6rlu	493	34	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	493	35	fatty	fatty	JJ
cord-353633-a4pu6rlu	493	36	liver	liver	NN
cord-353633-a4pu6rlu	493	37	disease	disease	NN
cord-353633-a4pu6rlu	493	38	A	a	DT
cord-353633-a4pu6rlu	493	39	comprehensive	comprehensive	JJ
cord-353633-a4pu6rlu	493	40	bioinformatics	bioinformatics	NN
cord-353633-a4pu6rlu	493	41	analysis	analysis	NN
cord-353633-a4pu6rlu	493	42	on	on	IN
cord-353633-a4pu6rlu	493	43	multiple	multiple	JJ
cord-353633-a4pu6rlu	493	44	Gene	Gene	NNP
cord-353633-a4pu6rlu	493	45	Expression	Expression	NNP
cord-353633-a4pu6rlu	493	46	Omnibus	Omnibus	NNP
cord-353633-a4pu6rlu	493	47	datasets	dataset	NNS
cord-353633-a4pu6rlu	493	48	of	of	IN
cord-353633-a4pu6rlu	493	49	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	493	50	fatty	fatty	JJ
cord-353633-a4pu6rlu	493	51	liver	liver	NN
cord-353633-a4pu6rlu	493	52	disease	disease	NN
cord-353633-a4pu6rlu	493	53	and	and	CC
cord-353633-a4pu6rlu	493	54	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	493	55	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	493	56	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	493	57	gene	gene	NN
cord-353633-a4pu6rlu	493	58	expression	expression	NN
cord-353633-a4pu6rlu	493	59	in	in	IN
cord-353633-a4pu6rlu	493	60	histologically	histologically	RB
cord-353633-a4pu6rlu	493	61	progressive	progressive	JJ
cord-353633-a4pu6rlu	493	62	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	493	63	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	493	64	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	493	65	gene	gene	NN
cord-353633-a4pu6rlu	493	66	expression	expression	NN
cord-353633-a4pu6rlu	493	67	in	in	IN
cord-353633-a4pu6rlu	493	68	patients	patient	NNS
cord-353633-a4pu6rlu	493	69	with	with	IN
cord-353633-a4pu6rlu	493	70	obesity	obesity	NN
cord-353633-a4pu6rlu	493	71	-	-	HYPH
cord-353633-a4pu6rlu	493	72	related	relate	VBN
cord-353633-a4pu6rlu	493	73	non	non	JJ
cord-353633-a4pu6rlu	493	74	-	-	JJ
cord-353633-a4pu6rlu	493	75	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	493	76	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	493	77	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	493	78	transcriptome	transcriptome	NN
cord-353633-a4pu6rlu	493	79	signatures	signature	NNS
cord-353633-a4pu6rlu	493	80	in	in	IN
cord-353633-a4pu6rlu	493	81	patients	patient	NNS
cord-353633-a4pu6rlu	493	82	with	with	IN
cord-353633-a4pu6rlu	493	83	varying	vary	VBG
cord-353633-a4pu6rlu	493	84	degrees	degree	NNS
cord-353633-a4pu6rlu	493	85	of	of	IN
cord-353633-a4pu6rlu	493	86	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	493	87	fatty	fatty	JJ
cord-353633-a4pu6rlu	493	88	liver	liver	NN
cord-353633-a4pu6rlu	493	89	disease	disease	NN
cord-353633-a4pu6rlu	493	90	compared	compare	VBN
cord-353633-a4pu6rlu	493	91	with	with	IN
cord-353633-a4pu6rlu	493	92	healthy	healthy	JJ
cord-353633-a4pu6rlu	493	93	normal	normal	JJ
cord-353633-a4pu6rlu	493	94	-	-	HYPH
cord-353633-a4pu6rlu	493	95	weight	weight	NN
cord-353633-a4pu6rlu	493	96	individuals	individual	NNS
cord-353633-a4pu6rlu	493	97	Gene	Gene	NNP
cord-353633-a4pu6rlu	493	98	expression	expression	NN
cord-353633-a4pu6rlu	493	99	profiling	profiling	NN
cord-353633-a4pu6rlu	493	100	unravels	unravel	VBZ
cord-353633-a4pu6rlu	493	101	cancer	cancer	NN
cord-353633-a4pu6rlu	493	102	-	-	HYPH
cord-353633-a4pu6rlu	493	103	related	relate	VBN
cord-353633-a4pu6rlu	493	104	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	493	105	molecular	molecular	JJ
cord-353633-a4pu6rlu	493	106	signatures	signature	NNS
cord-353633-a4pu6rlu	493	107	in	in	IN
cord-353633-a4pu6rlu	493	108	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	493	109	but	but	CC
cord-353633-a4pu6rlu	493	110	not	not	RB
cord-353633-a4pu6rlu	493	111	in	in	IN
cord-353633-a4pu6rlu	493	112	steatosis	steatosis	NN
cord-353633-a4pu6rlu	493	113	Gene	gene	NN
cord-353633-a4pu6rlu	493	114	expression	expression	NN
cord-353633-a4pu6rlu	493	115	profiling	profiling	NN
cord-353633-a4pu6rlu	493	116	of	of	IN
cord-353633-a4pu6rlu	493	117	non	non	JJ
cord-353633-a4pu6rlu	493	118	-	-	JJ
cord-353633-a4pu6rlu	493	119	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	493	120	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	493	121	using	use	VBG
cord-353633-a4pu6rlu	493	122	gene	gene	NN
cord-353633-a4pu6rlu	493	123	set	set	VBD
cord-353633-a4pu6rlu	493	124	enrichment	enrichment	NN
cord-353633-a4pu6rlu	493	125	analysis	analysis	NN
cord-353633-a4pu6rlu	493	126	Transcriptomic	Transcriptomic	NNP
cord-353633-a4pu6rlu	493	127	Profiling	Profiling	NNP
cord-353633-a4pu6rlu	493	128	of	of	IN
cord-353633-a4pu6rlu	493	129	Obesity	obesity	NN
cord-353633-a4pu6rlu	493	130	-	-	HYPH
cord-353633-a4pu6rlu	493	131	Related	Related	NNP
cord-353633-a4pu6rlu	493	132	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	493	133	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	493	134	Reveals	reveal	VBZ
cord-353633-a4pu6rlu	493	135	a	a	DT
cord-353633-a4pu6rlu	493	136	Core	Core	NNP
cord-353633-a4pu6rlu	493	137	Set	Set	NNP
cord-353633-a4pu6rlu	493	138	of	of	IN
cord-353633-a4pu6rlu	493	139	Fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	493	140	-	-	HYPH
cord-353633-a4pu6rlu	493	141	Specific	Specific	NNP
cord-353633-a4pu6rlu	493	142	Genes	Genes	NNPS
cord-353633-a4pu6rlu	493	143	Serum	Serum	NNP
cord-353633-a4pu6rlu	493	144	coding	code	VBG
cord-353633-a4pu6rlu	493	145	and	and	CC
cord-353633-a4pu6rlu	493	146	non	non	JJ
cord-353633-a4pu6rlu	493	147	-	-	JJ
cord-353633-a4pu6rlu	493	148	coding	coding	JJ
cord-353633-a4pu6rlu	493	149	RNAs	rna	NNS
cord-353633-a4pu6rlu	493	150	as	as	IN
cord-353633-a4pu6rlu	493	151	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	493	152	of	of	IN
cord-353633-a4pu6rlu	493	153	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	493	154	and	and	CC
cord-353633-a4pu6rlu	493	155	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	493	156	severity	severity	NN
cord-353633-a4pu6rlu	494	1	Interspecies	Interspecies	NNP
cord-353633-a4pu6rlu	494	2	NASH	NASH	NNP
cord-353633-a4pu6rlu	494	3	disease	disease	NN
cord-353633-a4pu6rlu	494	4	activity	activity	NN
cord-353633-a4pu6rlu	495	1	whole	whole	JJ
cord-353633-a4pu6rlu	495	2	-	-	HYPH
cord-353633-a4pu6rlu	495	3	genome	genome	NN
cord-353633-a4pu6rlu	495	4	profiling	profiling	NN
cord-353633-a4pu6rlu	495	5	identifies	identify	VBZ
cord-353633-a4pu6rlu	495	6	a	a	DT
cord-353633-a4pu6rlu	495	7	fibrogenic	fibrogenic	JJ
cord-353633-a4pu6rlu	495	8	role	role	NN
cord-353633-a4pu6rlu	495	9	of	of	IN
cord-353633-a4pu6rlu	495	10	PPARalpha	pparalpha	NN
cord-353633-a4pu6rlu	495	11	-	-	HYPH
cord-353633-a4pu6rlu	495	12	regulated	regulate	VBN
cord-353633-a4pu6rlu	495	13	dermatopontin	dermatopontin	JJ
cord-353633-a4pu6rlu	495	14	Role	role	NN
cord-353633-a4pu6rlu	495	15	of	of	IN
cord-353633-a4pu6rlu	495	16	Noncoding	Noncoding	NNP
cord-353633-a4pu6rlu	495	17	RNA	RNA	NNP
cord-353633-a4pu6rlu	495	18	in	in	IN
cord-353633-a4pu6rlu	495	19	Development	Development	NNP
cord-353633-a4pu6rlu	495	20	of	of	IN
cord-353633-a4pu6rlu	495	21	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	495	22	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	495	23	Liver	Liver	NNP
cord-353633-a4pu6rlu	495	24	Disease	Disease	NNP
cord-353633-a4pu6rlu	496	1	A	a	DT
cord-353633-a4pu6rlu	496	2	micro	micro	JJ
cord-353633-a4pu6rlu	496	3	-	-	JJ
cord-353633-a4pu6rlu	496	4	RNA	rna	JJ
cord-353633-a4pu6rlu	496	5	expression	expression	NN
cord-353633-a4pu6rlu	496	6	signature	signature	NN
cord-353633-a4pu6rlu	496	7	for	for	IN
cord-353633-a4pu6rlu	496	8	human	human	JJ
cord-353633-a4pu6rlu	496	9	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	496	10	progression	progression	NN
cord-353633-a4pu6rlu	497	1	Circulating	circulate	VBG
cord-353633-a4pu6rlu	497	2	microRNA	microRNA	NNP
cord-353633-a4pu6rlu	497	3	signature	signature	NN
cord-353633-a4pu6rlu	497	4	in	in	IN
cord-353633-a4pu6rlu	497	5	non	non	JJ
cord-353633-a4pu6rlu	497	6	-	-	JJ
cord-353633-a4pu6rlu	497	7	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	497	8	fatty	fatty	JJ
cord-353633-a4pu6rlu	497	9	liver	liver	NN
cord-353633-a4pu6rlu	497	10	disease	disease	NN
cord-353633-a4pu6rlu	497	11	:	:	:
cord-353633-a4pu6rlu	497	12	from	from	IN
cord-353633-a4pu6rlu	497	13	serum	serum	NN
cord-353633-a4pu6rlu	497	14	non	non	JJ
cord-353633-a4pu6rlu	497	15	-	-	JJ
cord-353633-a4pu6rlu	497	16	coding	coding	JJ
cord-353633-a4pu6rlu	497	17	RNAs	rna	NNS
cord-353633-a4pu6rlu	497	18	to	to	IN
cord-353633-a4pu6rlu	497	19	liver	liver	NN
cord-353633-a4pu6rlu	497	20	histology	histology	NN
cord-353633-a4pu6rlu	497	21	and	and	CC
cord-353633-a4pu6rlu	497	22	disease	disease	NN
cord-353633-a4pu6rlu	497	23	pathogenesis	pathogenesis	NN
cord-353633-a4pu6rlu	497	24	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	497	25	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	497	26	is	be	VBZ
cord-353633-a4pu6rlu	497	27	associated	associate	VBN
cord-353633-a4pu6rlu	497	28	with	with	IN
cord-353633-a4pu6rlu	497	29	altered	altered	JJ
cord-353633-a4pu6rlu	497	30	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	497	31	MicroRNA	MicroRNA	NNP
cord-353633-a4pu6rlu	497	32	expression	expression	NN
cord-353633-a4pu6rlu	497	33	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	497	34	Signature	Signature	NNP
cord-353633-a4pu6rlu	497	35	in	in	IN
cord-353633-a4pu6rlu	497	36	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	497	37	:	:	:
cord-353633-a4pu6rlu	498	1	A	a	DT
cord-353633-a4pu6rlu	498	2	Turning	turning	NN
cord-353633-a4pu6rlu	498	3	Point	point	NN
cord-353633-a4pu6rlu	498	4	for	for	IN
cord-353633-a4pu6rlu	498	5	a	a	DT
cord-353633-a4pu6rlu	498	6	Non	non	JJ
cord-353633-a4pu6rlu	498	7	-	-	JJ
cord-353633-a4pu6rlu	498	8	Invasive	invasive	JJ
cord-353633-a4pu6rlu	498	9	Diagnosis	Diagnosis	NNP
cord-353633-a4pu6rlu	498	10	Liver	liver	NN
cord-353633-a4pu6rlu	498	11	-	-	HYPH
cord-353633-a4pu6rlu	498	12	specific	specific	JJ
cord-353633-a4pu6rlu	498	13	microRNA-122	microrna-122	NN
cord-353633-a4pu6rlu	498	14	:	:	:
cord-353633-a4pu6rlu	499	1	Biogenesis	biogenesis	NN
cord-353633-a4pu6rlu	499	2	and	and	CC
cord-353633-a4pu6rlu	499	3	function	function	VB
cord-353633-a4pu6rlu	499	4	Associations	association	NNS
cord-353633-a4pu6rlu	499	5	between	between	IN
cord-353633-a4pu6rlu	499	6	circulating	circulate	VBG
cord-353633-a4pu6rlu	499	7	microRNAs	microRNAs	NNPS
cord-353633-a4pu6rlu	499	8	(	(	-LRB-
cord-353633-a4pu6rlu	499	9	miR-21	mir-21	JJ
cord-353633-a4pu6rlu	499	10	,	,	,
cord-353633-a4pu6rlu	499	11	miR-34a	miR-34a	NNP
cord-353633-a4pu6rlu	499	12	,	,	,
cord-353633-a4pu6rlu	499	13	miR-122	miR-122	NNP
cord-353633-a4pu6rlu	499	14	and	and	CC
cord-353633-a4pu6rlu	499	15	miR-451	miR-451	NNP
cord-353633-a4pu6rlu	499	16	)	)	-RRB-
cord-353633-a4pu6rlu	499	17	and	and	CC
cord-353633-a4pu6rlu	499	18	non	non	JJ
cord-353633-a4pu6rlu	499	19	-	-	JJ
cord-353633-a4pu6rlu	499	20	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	499	21	fatty	fatty	JJ
cord-353633-a4pu6rlu	499	22	liver	liver	NN
cord-353633-a4pu6rlu	500	1	Circulating	circulate	VBG
cord-353633-a4pu6rlu	500	2	microRNAs	microrna	NNS
cord-353633-a4pu6rlu	500	3	in	in	IN
cord-353633-a4pu6rlu	500	4	patients	patient	NNS
cord-353633-a4pu6rlu	500	5	with	with	IN
cord-353633-a4pu6rlu	500	6	chronic	chronic	JJ
cord-353633-a4pu6rlu	500	7	hepatitis	hepatitis	NN
cord-353633-a4pu6rlu	500	8	C	c	NN
cord-353633-a4pu6rlu	500	9	and	and	CC
cord-353633-a4pu6rlu	500	10	non	non	JJ
cord-353633-a4pu6rlu	500	11	-	-	JJ
cord-353633-a4pu6rlu	500	12	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	500	13	fatty	fatty	JJ
cord-353633-a4pu6rlu	500	14	liver	liver	NN
cord-353633-a4pu6rlu	500	15	disease	disease	NN
cord-353633-a4pu6rlu	500	16	Genome	Genome	NNP
cord-353633-a4pu6rlu	500	17	-	-	HYPH
cord-353633-a4pu6rlu	500	18	wide	wide	JJ
cord-353633-a4pu6rlu	500	19	analysis	analysis	NN
cord-353633-a4pu6rlu	500	20	of	of	IN
cord-353633-a4pu6rlu	500	21	long	long	JJ
cord-353633-a4pu6rlu	500	22	noncoding	noncoding	JJ
cord-353633-a4pu6rlu	500	23	RNA	RNA	NNP
cord-353633-a4pu6rlu	500	24	expression	expression	NN
cord-353633-a4pu6rlu	500	25	profiles	profile	NNS
cord-353633-a4pu6rlu	500	26	in	in	IN
cord-353633-a4pu6rlu	500	27	patients	patient	NNS
cord-353633-a4pu6rlu	500	28	with	with	IN
cord-353633-a4pu6rlu	500	29	non	non	JJ
cord-353633-a4pu6rlu	500	30	-	-	JJ
cord-353633-a4pu6rlu	500	31	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	500	32	fatty	fatty	JJ
cord-353633-a4pu6rlu	500	33	liver	liver	NN
cord-353633-a4pu6rlu	500	34	disease	disease	NN
cord-353633-a4pu6rlu	500	35	A	a	DT
cord-353633-a4pu6rlu	500	36	liver	liver	NN
cord-353633-a4pu6rlu	500	37	-	-	HYPH
cord-353633-a4pu6rlu	500	38	specific	specific	JJ
cord-353633-a4pu6rlu	500	39	long	long	JJ
cord-353633-a4pu6rlu	500	40	noncoding	noncoding	JJ
cord-353633-a4pu6rlu	500	41	RNA	RNA	NNP
cord-353633-a4pu6rlu	500	42	with	with	IN
cord-353633-a4pu6rlu	500	43	a	a	DT
cord-353633-a4pu6rlu	500	44	role	role	NN
cord-353633-a4pu6rlu	500	45	in	in	IN
cord-353633-a4pu6rlu	500	46	cell	cell	NN
cord-353633-a4pu6rlu	500	47	viability	viability	NN
cord-353633-a4pu6rlu	500	48	is	be	VBZ
cord-353633-a4pu6rlu	500	49	elevated	elevate	VBN
cord-353633-a4pu6rlu	500	50	in	in	IN
cord-353633-a4pu6rlu	500	51	human	human	JJ
cord-353633-a4pu6rlu	500	52	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	500	53	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	500	54	Impact	Impact	NNP
cord-353633-a4pu6rlu	500	55	of	of	IN
cord-353633-a4pu6rlu	500	56	long	long	JJ
cord-353633-a4pu6rlu	500	57	-	-	HYPH
cord-353633-a4pu6rlu	500	58	term	term	NN
cord-353633-a4pu6rlu	500	59	storage	storage	NN
cord-353633-a4pu6rlu	500	60	and	and	CC
cord-353633-a4pu6rlu	500	61	freeze	freeze	NN
cord-353633-a4pu6rlu	500	62	-	-	HYPH
cord-353633-a4pu6rlu	500	63	thawing	thaw	VBG
cord-353633-a4pu6rlu	500	64	on	on	IN
cord-353633-a4pu6rlu	500	65	eight	eight	CD
cord-353633-a4pu6rlu	500	66	circulating	circulate	VBG
cord-353633-a4pu6rlu	500	67	microRNAs	microrna	NNS
cord-353633-a4pu6rlu	500	68	in	in	IN
cord-353633-a4pu6rlu	500	69	plasma	plasma	NN
cord-353633-a4pu6rlu	500	70	samples	sample	NNS
cord-353633-a4pu6rlu	501	1	A	a	DT
cord-353633-a4pu6rlu	501	2	pilot	pilot	NN
cord-353633-a4pu6rlu	501	3	study	study	NN
cord-353633-a4pu6rlu	501	4	of	of	IN
cord-353633-a4pu6rlu	501	5	serum	serum	NN
cord-353633-a4pu6rlu	501	6	microRNAs	micrornas	JJ
cord-353633-a4pu6rlu	501	7	panel	panel	NN
cord-353633-a4pu6rlu	501	8	as	as	IN
cord-353633-a4pu6rlu	501	9	potential	potential	JJ
cord-353633-a4pu6rlu	501	10	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	501	11	for	for	IN
cord-353633-a4pu6rlu	501	12	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	501	13	of	of	IN
cord-353633-a4pu6rlu	501	14	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	501	15	fatty	fatty	JJ
cord-353633-a4pu6rlu	501	16	liver	liver	NN
cord-353633-a4pu6rlu	501	17	disease	disease	NN
cord-353633-a4pu6rlu	502	1	The	the	DT
cord-353633-a4pu6rlu	503	1	Circulating	circulate	VBG
cord-353633-a4pu6rlu	503	2	Micro	Micro	NNP
cord-353633-a4pu6rlu	503	3	-	-	HYPH
cord-353633-a4pu6rlu	503	4	RNAs	RNAs	NNPS
cord-353633-a4pu6rlu	504	1	(	(	-LRB-
cord-353633-a4pu6rlu	504	2	-122	-122	FW
cord-353633-a4pu6rlu	504	3	,	,	,
cord-353633-a4pu6rlu	504	4	-34a	-34a	CD
cord-353633-a4pu6rlu	504	5	and	and	CC
cord-353633-a4pu6rlu	504	6	-99a	-99a	ADD
cord-353633-a4pu6rlu	504	7	)	)	-RRB-
cord-353633-a4pu6rlu	504	8	as	as	IN
cord-353633-a4pu6rlu	504	9	Predictive	Predictive	NNP
cord-353633-a4pu6rlu	504	10	Biomarkers	Biomarkers	NNPS
cord-353633-a4pu6rlu	504	11	for	for	IN
cord-353633-a4pu6rlu	504	12	Non	non	JJ
cord-353633-a4pu6rlu	504	13	-	-	JJ
cord-353633-a4pu6rlu	504	14	Alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	504	15	Fatty	fatty	JJ
cord-353633-a4pu6rlu	504	16	Liver	liver	NN
cord-353633-a4pu6rlu	504	17	Diseases	Diseases	NNPS
cord-353633-a4pu6rlu	504	18	miRNAs	miRNAs	NNP
cord-353633-a4pu6rlu	504	19	in	in	IN
cord-353633-a4pu6rlu	504	20	patients	patient	NNS
cord-353633-a4pu6rlu	504	21	with	with	IN
cord-353633-a4pu6rlu	504	22	non	non	JJ
cord-353633-a4pu6rlu	504	23	-	-	JJ
cord-353633-a4pu6rlu	504	24	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	504	25	fatty	fatty	JJ
cord-353633-a4pu6rlu	504	26	liver	liver	NN
cord-353633-a4pu6rlu	504	27	disease	disease	NN
cord-353633-a4pu6rlu	504	28	:	:	:
cord-353633-a4pu6rlu	504	29	A	a	DT
cord-353633-a4pu6rlu	504	30	systematic	systematic	JJ
cord-353633-a4pu6rlu	504	31	review	review	NN
cord-353633-a4pu6rlu	504	32	and	and	CC
cord-353633-a4pu6rlu	504	33	meta	meta	NNP
cord-353633-a4pu6rlu	504	34	-	-	HYPH
cord-353633-a4pu6rlu	504	35	analysis	analysis	NN
cord-353633-a4pu6rlu	504	36	GENFIT	GENFIT	NNP
cord-353633-a4pu6rlu	504	37	-	-	HYPH
cord-353633-a4pu6rlu	504	38	Announces	announce	NNS
cord-353633-a4pu6rlu	504	39	-	-	HYPH
cord-353633-a4pu6rlu	504	40	Results	Results	NNP
cord-353633-a4pu6rlu	504	41	-	-	HYPH
cord-353633-a4pu6rlu	504	42	of	of	IN
cord-353633-a4pu6rlu	504	43	-	-	HYPH
cord-353633-a4pu6rlu	504	44	NIS4-an	nis4-an	NN
cord-353633-a4pu6rlu	504	45	-	-	HYPH
cord-353633-a4pu6rlu	504	46	Investigational	Investigational	NNP
cord-353633-a4pu6rlu	504	47	-	-	HYPH
cord-353633-a4pu6rlu	504	48	Non	non	JJ
cord-353633-a4pu6rlu	504	49	-	-	JJ
cord-353633-a4pu6rlu	504	50	Invasive	invasive	JJ
cord-353633-a4pu6rlu	504	51	-	-	HYPH
cord-353633-a4pu6rlu	504	52	NASH	NASH	NNP
cord-353633-a4pu6rlu	504	53	-	-	HYPH
cord-353633-a4pu6rlu	504	54	Diagnostic	Diagnostic	NNP
cord-353633-a4pu6rlu	504	55	-	-	HYPH
cord-353633-a4pu6rlu	504	56	at	at	IN
cord-353633-a4pu6rlu	504	57	-	-	HYPH
cord-353633-a4pu6rlu	504	58	AASLD-2019.html	aasld-2019.html	NN
cord-353633-a4pu6rlu	504	59	Validation	validation	NN
cord-353633-a4pu6rlu	504	60	of	of	IN
cord-353633-a4pu6rlu	504	61	NIS4	NIS4	NNP
cord-353633-a4pu6rlu	504	62	algorithm	algorithm	NN
cord-353633-a4pu6rlu	504	63	for	for	IN
cord-353633-a4pu6rlu	504	64	detection	detection	NN
cord-353633-a4pu6rlu	504	65	of	of	IN
cord-353633-a4pu6rlu	504	66	NASH	NASH	NNP
cord-353633-a4pu6rlu	504	67	at	at	IN
cord-353633-a4pu6rlu	504	68	risk	risk	NN
cord-353633-a4pu6rlu	504	69	of	of	IN
cord-353633-a4pu6rlu	504	70	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	504	71	in	in	IN
cord-353633-a4pu6rlu	504	72	467	467	CD
cord-353633-a4pu6rlu	504	73	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	504	74	patients	patient	NNS
cord-353633-a4pu6rlu	504	75	prospectively	prospectively	RB
cord-353633-a4pu6rlu	504	76	screened	screen	VBN
cord-353633-a4pu6rlu	504	77	for	for	IN
cord-353633-a4pu6rlu	504	78	inclusion	inclusion	NN
cord-353633-a4pu6rlu	504	79	in	in	IN
cord-353633-a4pu6rlu	504	80	the	the	DT
cord-353633-a4pu6rlu	504	81	RESOLVE	resolve	NN
cord-353633-a4pu6rlu	504	82	-	-	HYPH
cord-353633-a4pu6rlu	504	83	IT	IT	NNP
cord-353633-a4pu6rlu	504	84	trial	trial	NN
cord-353633-a4pu6rlu	504	85	Performance	performance	NN
cord-353633-a4pu6rlu	504	86	of	of	IN
cord-353633-a4pu6rlu	504	87	Serum	Serum	NNP
cord-353633-a4pu6rlu	504	88	microRNAs	microRNAs	NNP
cord-353633-a4pu6rlu	504	89	-122	-122	FW
cord-353633-a4pu6rlu	504	90	,	,	,
cord-353633-a4pu6rlu	504	91	-192	-192	NNP
cord-353633-a4pu6rlu	505	1	and	and	CC
cord-353633-a4pu6rlu	505	2	-21	-21	IN
cord-353633-a4pu6rlu	505	3	as	as	IN
cord-353633-a4pu6rlu	505	4	Biomarkers	Biomarkers	NNPS
cord-353633-a4pu6rlu	505	5	in	in	IN
cord-353633-a4pu6rlu	505	6	Patients	patient	NNS
cord-353633-a4pu6rlu	505	7	with	with	IN
cord-353633-a4pu6rlu	505	8	Non	Non	NNP
cord-353633-a4pu6rlu	505	9	-	-	NNP
cord-353633-a4pu6rlu	505	10	Alcoholic	Alcoholic	NNP
cord-353633-a4pu6rlu	505	11	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	505	12	CircRNA	CircRNA	NNP
cord-353633-a4pu6rlu	505	13	expression	expression	NN
cord-353633-a4pu6rlu	505	14	pattern	pattern	NN
cord-353633-a4pu6rlu	505	15	and	and	CC
cord-353633-a4pu6rlu	506	1	circRNA	circRNA	NNP
cord-353633-a4pu6rlu	506	2	-	-	HYPH
cord-353633-a4pu6rlu	506	3	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	506	4	-	-	HYPH
cord-353633-a4pu6rlu	506	5	mRNA	mRNA	NNP
cord-353633-a4pu6rlu	506	6	network	network	NN
cord-353633-a4pu6rlu	506	7	in	in	IN
cord-353633-a4pu6rlu	506	8	the	the	DT
cord-353633-a4pu6rlu	506	9	pathogenesis	pathogenesis	NN
cord-353633-a4pu6rlu	506	10	of	of	IN
cord-353633-a4pu6rlu	506	11	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	506	12	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	506	13	Comprehensive	Comprehensive	NNP
cord-353633-a4pu6rlu	506	14	circular	circular	JJ
cord-353633-a4pu6rlu	506	15	RNA	RNA	NNP
cord-353633-a4pu6rlu	506	16	expression	expression	NN
cord-353633-a4pu6rlu	506	17	profiles	profile	NNS
cord-353633-a4pu6rlu	506	18	in	in	IN
cord-353633-a4pu6rlu	506	19	a	a	DT
cord-353633-a4pu6rlu	506	20	mouse	mouse	NN
cord-353633-a4pu6rlu	506	21	model	model	NN
cord-353633-a4pu6rlu	506	22	of	of	IN
cord-353633-a4pu6rlu	506	23	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	506	24	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	506	25	Alternative	Alternative	NNP
cord-353633-a4pu6rlu	506	26	RNA	RNA	NNP
cord-353633-a4pu6rlu	506	27	Splicing	Splicing	NNP
cord-353633-a4pu6rlu	506	28	in	in	IN
cord-353633-a4pu6rlu	506	29	the	the	DT
cord-353633-a4pu6rlu	506	30	Pathogenesis	Pathogenesis	NNP
cord-353633-a4pu6rlu	506	31	of	of	IN
cord-353633-a4pu6rlu	506	32	Liver	Liver	NNP
cord-353633-a4pu6rlu	506	33	Disease	Disease	NNP
cord-353633-a4pu6rlu	506	34	Mechanisms	Mechanisms	NNPS
cord-353633-a4pu6rlu	506	35	of	of	IN
cord-353633-a4pu6rlu	506	36	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	506	37	development	development	NN
cord-353633-a4pu6rlu	506	38	and	and	CC
cord-353633-a4pu6rlu	506	39	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	506	40	strategies	strategy	NNS
cord-353633-a4pu6rlu	506	41	Mapping	map	VBG
cord-353633-a4pu6rlu	506	42	the	the	DT
cord-353633-a4pu6rlu	506	43	molecular	molecular	JJ
cord-353633-a4pu6rlu	506	44	signatures	signature	NNS
cord-353633-a4pu6rlu	506	45	of	of	IN
cord-353633-a4pu6rlu	506	46	diet	diet	NN
cord-353633-a4pu6rlu	506	47	-	-	HYPH
cord-353633-a4pu6rlu	506	48	induced	induce	VBN
cord-353633-a4pu6rlu	506	49	NASH	NASH	NNP
cord-353633-a4pu6rlu	506	50	and	and	CC
cord-353633-a4pu6rlu	506	51	its	-PRON-	PRP$
cord-353633-a4pu6rlu	506	52	regulation	regulation	NN
cord-353633-a4pu6rlu	506	53	by	by	IN
cord-353633-a4pu6rlu	506	54	the	the	DT
cord-353633-a4pu6rlu	506	55	hepatokine	hepatokine	NN
cord-353633-a4pu6rlu	506	56	Tsukushi	Tsukushi	NNP
cord-353633-a4pu6rlu	506	57	Iron	Iron	NNP
cord-353633-a4pu6rlu	506	58	chaperone	chaperone	NN
cord-353633-a4pu6rlu	506	59	PCBP1	PCBP1	NNS
cord-353633-a4pu6rlu	506	60	protects	protect	VBZ
cord-353633-a4pu6rlu	506	61	murine	murine	JJ
cord-353633-a4pu6rlu	506	62	liver	liver	NN
cord-353633-a4pu6rlu	506	63	from	from	IN
cord-353633-a4pu6rlu	506	64	lipid	lipid	JJ
cord-353633-a4pu6rlu	506	65	peroxidation	peroxidation	NN
cord-353633-a4pu6rlu	506	66	and	and	CC
cord-353633-a4pu6rlu	506	67	steatosis	steatosis	NN
cord-353633-a4pu6rlu	506	68	No	no	DT
cord-353633-a4pu6rlu	506	69	evidence	evidence	NN
cord-353633-a4pu6rlu	506	70	for	for	IN
cord-353633-a4pu6rlu	506	71	an	an	DT
cord-353633-a4pu6rlu	506	72	increased	increase	VBN
cord-353633-a4pu6rlu	506	73	liver	liver	NN
cord-353633-a4pu6rlu	506	74	uptake	uptake	NN
cord-353633-a4pu6rlu	506	75	of	of	IN
cord-353633-a4pu6rlu	506	76	SARS	SARS	NNP
cord-353633-a4pu6rlu	506	77	-	-	HYPH
cord-353633-a4pu6rlu	506	78	CoV-2	CoV-2	NNP
cord-353633-a4pu6rlu	506	79	in	in	IN
cord-353633-a4pu6rlu	506	80	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	506	81	associated	associate	VBD
cord-353633-a4pu6rlu	506	82	fatty	fatty	JJ
cord-353633-a4pu6rlu	506	83	liver	liver	NN
cord-353633-a4pu6rlu	506	84	disease	disease	NN
cord-353633-a4pu6rlu	506	85	Omics	Omics	NNP
cord-353633-a4pu6rlu	506	86	,	,	,
cord-353633-a4pu6rlu	506	87	big	big	JJ
cord-353633-a4pu6rlu	506	88	data	datum	NNS
cord-353633-a4pu6rlu	506	89	and	and	CC
cord-353633-a4pu6rlu	506	90	machine	machine	NN
cord-353633-a4pu6rlu	506	91	learning	learning	NN
cord-353633-a4pu6rlu	506	92	as	as	IN
cord-353633-a4pu6rlu	506	93	tools	tool	NNS
cord-353633-a4pu6rlu	506	94	to	to	TO
cord-353633-a4pu6rlu	506	95	propel	propel	VB
cord-353633-a4pu6rlu	506	96	understanding	understanding	NN
cord-353633-a4pu6rlu	506	97	of	of	IN
cord-353633-a4pu6rlu	506	98	biological	biological	JJ
cord-353633-a4pu6rlu	506	99	mechanisms	mechanism	NNS
cord-353633-a4pu6rlu	506	100	and	and	CC
cord-353633-a4pu6rlu	506	101	to	to	TO
cord-353633-a4pu6rlu	506	102	discover	discover	VB
cord-353633-a4pu6rlu	506	103	novel	novel	JJ
cord-353633-a4pu6rlu	506	104	diagnostics	diagnostic	NNS
cord-353633-a4pu6rlu	506	105	and	and	CC
cord-353633-a4pu6rlu	506	106	therapeutics	therapeutic	NNS
cord-353633-a4pu6rlu	506	107	Revisiting	revisit	VBG
cord-353633-a4pu6rlu	506	108	biomarker	biomarker	NN
cord-353633-a4pu6rlu	506	109	discovery	discovery	NN
cord-353633-a4pu6rlu	506	110	by	by	IN
cord-353633-a4pu6rlu	506	111	plasma	plasma	NN
cord-353633-a4pu6rlu	506	112	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	507	1	An	an	DT
cord-353633-a4pu6rlu	507	2	exploratory	exploratory	JJ
cord-353633-a4pu6rlu	507	3	study	study	NN
cord-353633-a4pu6rlu	507	4	examining	examine	VBG
cord-353633-a4pu6rlu	507	5	how	how	WRB
cord-353633-a4pu6rlu	507	6	nano	nano	NN
cord-353633-a4pu6rlu	507	7	-	-	HYPH
cord-353633-a4pu6rlu	507	8	liquid	liquid	JJ
cord-353633-a4pu6rlu	507	9	chromatography	chromatography	NN
cord-353633-a4pu6rlu	507	10	-	-	HYPH
cord-353633-a4pu6rlu	507	11	mass	mass	NN
cord-353633-a4pu6rlu	507	12	spectrometry	spectrometry	NN
cord-353633-a4pu6rlu	507	13	and	and	CC
cord-353633-a4pu6rlu	507	14	phosphoproteomics	phosphoproteomic	NNS
cord-353633-a4pu6rlu	507	15	can	can	MD
cord-353633-a4pu6rlu	507	16	differentiate	differentiate	VB
cord-353633-a4pu6rlu	507	17	patients	patient	NNS
cord-353633-a4pu6rlu	507	18	with	with	IN
cord-353633-a4pu6rlu	507	19	advanced	advanced	JJ
cord-353633-a4pu6rlu	507	20	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	507	21	and	and	CC
cord-353633-a4pu6rlu	507	22	higher	high	JJR
cord-353633-a4pu6rlu	507	23	percentage	percentage	NN
cord-353633-a4pu6rlu	507	24	collagen	collagen	NN
cord-353633-a4pu6rlu	507	25	in	in	IN
cord-353633-a4pu6rlu	507	26	non	non	JJ
cord-353633-a4pu6rlu	507	27	-	-	JJ
cord-353633-a4pu6rlu	507	28	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	507	29	fatty	fatty	JJ
cord-353633-a4pu6rlu	507	30	liver	liver	NN
cord-353633-a4pu6rlu	507	31	disease	disease	NN
cord-353633-a4pu6rlu	507	32	Proteomic	Proteomic	NNP
cord-353633-a4pu6rlu	507	33	analysis	analysis	NN
cord-353633-a4pu6rlu	507	34	to	to	TO
cord-353633-a4pu6rlu	507	35	identify	identify	VB
cord-353633-a4pu6rlu	507	36	differentially	differentially	RB
cord-353633-a4pu6rlu	507	37	expressed	express	VBN
cord-353633-a4pu6rlu	507	38	proteins	protein	NNS
cord-353633-a4pu6rlu	507	39	between	between	IN
cord-353633-a4pu6rlu	507	40	subjects	subject	NNS
cord-353633-a4pu6rlu	507	41	with	with	IN
cord-353633-a4pu6rlu	507	42	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	507	43	healthy	healthy	JJ
cord-353633-a4pu6rlu	507	44	obesity	obesity	NN
cord-353633-a4pu6rlu	507	45	and	and	CC
cord-353633-a4pu6rlu	507	46	non	non	JJ
cord-353633-a4pu6rlu	507	47	-	-	JJ
cord-353633-a4pu6rlu	507	48	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	507	49	fatty	fatty	JJ
cord-353633-a4pu6rlu	507	50	liver	liver	NN
cord-353633-a4pu6rlu	507	51	disease	disease	NN
cord-353633-a4pu6rlu	508	1	Organellar	Organellar	NNP
cord-353633-a4pu6rlu	508	2	Proteomics	Proteomics	NNP
cord-353633-a4pu6rlu	508	3	and	and	CC
cord-353633-a4pu6rlu	508	4	Phospho	Phospho	NNP
cord-353633-a4pu6rlu	508	5	-	-	HYPH
cord-353633-a4pu6rlu	508	6	Proteomics	Proteomics	NNP
cord-353633-a4pu6rlu	509	1	Reveal	reveal	VB
cord-353633-a4pu6rlu	509	2	Subcellular	Subcellular	NNP
cord-353633-a4pu6rlu	509	3	Reorganization	Reorganization	NNP
cord-353633-a4pu6rlu	509	4	in	in	IN
cord-353633-a4pu6rlu	509	5	Diet	Diet	NNP
cord-353633-a4pu6rlu	509	6	-	-	HYPH
cord-353633-a4pu6rlu	509	7	Induced	Induced	NNP
cord-353633-a4pu6rlu	509	8	Hepatic	Hepatic	NNP
cord-353633-a4pu6rlu	509	9	Steatosis	Steatosis	NNP
cord-353633-a4pu6rlu	509	10	Identification	Identification	NNP
cord-353633-a4pu6rlu	509	11	of	of	IN
cord-353633-a4pu6rlu	509	12	liver	liver	NN
cord-353633-a4pu6rlu	509	13	proteins	protein	NNS
cord-353633-a4pu6rlu	509	14	altered	alter	VBN
cord-353633-a4pu6rlu	509	15	by	by	IN
cord-353633-a4pu6rlu	509	16	type	type	NN
cord-353633-a4pu6rlu	509	17	2	2	CD
cord-353633-a4pu6rlu	509	18	diabetes	diabetes	NN
cord-353633-a4pu6rlu	509	19	mellitus	mellitus	NN
cord-353633-a4pu6rlu	509	20	in	in	IN
cord-353633-a4pu6rlu	509	21	obese	obese	JJ
cord-353633-a4pu6rlu	509	22	subjects	subject	NNS
cord-353633-a4pu6rlu	509	23	A	a	DT
cord-353633-a4pu6rlu	509	24	genomic	genomic	JJ
cord-353633-a4pu6rlu	509	25	and	and	CC
cord-353633-a4pu6rlu	509	26	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	509	27	study	study	NN
cord-353633-a4pu6rlu	509	28	of	of	IN
cord-353633-a4pu6rlu	509	29	the	the	DT
cord-353633-a4pu6rlu	509	30	spectrum	spectrum	NN
cord-353633-a4pu6rlu	509	31	of	of	IN
cord-353633-a4pu6rlu	509	32	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	509	33	fatty	fatty	JJ
cord-353633-a4pu6rlu	509	34	liver	liver	NN
cord-353633-a4pu6rlu	509	35	disease	disease	NN
cord-353633-a4pu6rlu	509	36	Serum	serum	NN
cord-353633-a4pu6rlu	509	37	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	509	38	profiling	profiling	NN
cord-353633-a4pu6rlu	509	39	of	of	IN
cord-353633-a4pu6rlu	509	40	obese	obese	JJ
cord-353633-a4pu6rlu	509	41	patients	patient	NNS
cord-353633-a4pu6rlu	509	42	:	:	:
cord-353633-a4pu6rlu	509	43	correlation	correlation	NN
cord-353633-a4pu6rlu	509	44	with	with	IN
cord-353633-a4pu6rlu	509	45	liver	liver	NN
cord-353633-a4pu6rlu	509	46	pathology	pathology	NN
cord-353633-a4pu6rlu	509	47	and	and	CC
cord-353633-a4pu6rlu	509	48	evolution	evolution	NN
cord-353633-a4pu6rlu	509	49	after	after	IN
cord-353633-a4pu6rlu	509	50	bariatric	bariatric	JJ
cord-353633-a4pu6rlu	509	51	surgery	surgery	NN
cord-353633-a4pu6rlu	509	52	Targeted	Targeted	NNP
cord-353633-a4pu6rlu	509	53	Analysis	Analysis	NNP
cord-353633-a4pu6rlu	509	54	of	of	IN
cord-353633-a4pu6rlu	509	55	Three	Three	NNP
cord-353633-a4pu6rlu	509	56	Hormonal	Hormonal	NNP
cord-353633-a4pu6rlu	509	57	Systems	Systems	NNPS
cord-353633-a4pu6rlu	510	1	Identifies	identify	VBZ
cord-353633-a4pu6rlu	510	2	Molecules	molecule	NNS
cord-353633-a4pu6rlu	510	3	Associated	associate	VBN
cord-353633-a4pu6rlu	510	4	with	with	IN
cord-353633-a4pu6rlu	510	5	the	the	DT
cord-353633-a4pu6rlu	510	6	Presence	Presence	NNP
cord-353633-a4pu6rlu	510	7	and	and	CC
cord-353633-a4pu6rlu	510	8	Severity	severity	NN
cord-353633-a4pu6rlu	510	9	of	of	IN
cord-353633-a4pu6rlu	510	10	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	510	11	A	a	DT
cord-353633-a4pu6rlu	510	12	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	510	13	strategy	strategy	NN
cord-353633-a4pu6rlu	510	14	to	to	TO
cord-353633-a4pu6rlu	510	15	identify	identify	VB
cord-353633-a4pu6rlu	510	16	novel	novel	JJ
cord-353633-a4pu6rlu	510	17	serum	serum	NN
cord-353633-a4pu6rlu	510	18	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	510	19	for	for	IN
cord-353633-a4pu6rlu	510	20	liver	liver	NN
cord-353633-a4pu6rlu	510	21	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	510	22	and	and	CC
cord-353633-a4pu6rlu	510	23	hepatocellular	hepatocellular	JJ
cord-353633-a4pu6rlu	510	24	cancer	cancer	NN
cord-353633-a4pu6rlu	510	25	in	in	IN
cord-353633-a4pu6rlu	510	26	individuals	individual	NNS
cord-353633-a4pu6rlu	510	27	with	with	IN
cord-353633-a4pu6rlu	510	28	fatty	fatty	JJ
cord-353633-a4pu6rlu	510	29	liver	liver	NN
cord-353633-a4pu6rlu	510	30	disease	disease	NN
cord-353633-a4pu6rlu	510	31	Serum	serum	NN
cord-353633-a4pu6rlu	510	32	proteomics	proteomic	NNS
cord-353633-a4pu6rlu	510	33	and	and	CC
cord-353633-a4pu6rlu	510	34	biomarker	biomarker	NN
cord-353633-a4pu6rlu	510	35	discovery	discovery	NN
cord-353633-a4pu6rlu	510	36	across	across	IN
cord-353633-a4pu6rlu	510	37	the	the	DT
cord-353633-a4pu6rlu	510	38	spectrum	spectrum	NN
cord-353633-a4pu6rlu	510	39	of	of	IN
cord-353633-a4pu6rlu	510	40	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	510	41	fatty	fatty	JJ
cord-353633-a4pu6rlu	510	42	liver	liver	NN
cord-353633-a4pu6rlu	510	43	disease	disease	NN
cord-353633-a4pu6rlu	511	1	A	a	DT
cord-353633-a4pu6rlu	511	2	multi	multi	JJ
cord-353633-a4pu6rlu	511	3	-	-	JJ
cord-353633-a4pu6rlu	511	4	component	component	JJ
cord-353633-a4pu6rlu	511	5	classifier	classifier	NN
cord-353633-a4pu6rlu	511	6	for	for	IN
cord-353633-a4pu6rlu	511	7	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	511	8	fatty	fatty	JJ
cord-353633-a4pu6rlu	511	9	liver	liver	NN
cord-353633-a4pu6rlu	511	10	disease	disease	NN
cord-353633-a4pu6rlu	511	11	(	(	-LRB-
cord-353633-a4pu6rlu	511	12	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	511	13	)	)	-RRB-
cord-353633-a4pu6rlu	511	14	based	base	VBN
cord-353633-a4pu6rlu	511	15	on	on	IN
cord-353633-a4pu6rlu	511	16	genomic	genomic	JJ
cord-353633-a4pu6rlu	511	17	,	,	,
cord-353633-a4pu6rlu	511	18	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	511	19	,	,	,
cord-353633-a4pu6rlu	511	20	and	and	CC
cord-353633-a4pu6rlu	511	21	phenomic	phenomic	NNP
cord-353633-a4pu6rlu	511	22	data	datum	NNS
cord-353633-a4pu6rlu	511	23	domains	domain	NNS
cord-353633-a4pu6rlu	512	1	Elevated	elevated	JJ
cord-353633-a4pu6rlu	512	2	levels	level	NNS
cord-353633-a4pu6rlu	512	3	of	of	IN
cord-353633-a4pu6rlu	512	4	circulating	circulate	VBG
cord-353633-a4pu6rlu	512	5	ITIH4	ITIH4	NNP
cord-353633-a4pu6rlu	512	6	are	be	VBP
cord-353633-a4pu6rlu	512	7	associated	associate	VBN
cord-353633-a4pu6rlu	512	8	with	with	IN
cord-353633-a4pu6rlu	512	9	hepatocellular	hepatocellular	JJ
cord-353633-a4pu6rlu	512	10	carcinoma	carcinoma	NN
cord-353633-a4pu6rlu	512	11	with	with	IN
cord-353633-a4pu6rlu	512	12	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	512	13	fatty	fatty	JJ
cord-353633-a4pu6rlu	512	14	liver	liver	NN
cord-353633-a4pu6rlu	512	15	disease	disease	NN
cord-353633-a4pu6rlu	512	16	:	:	:
cord-353633-a4pu6rlu	512	17	from	from	IN
cord-353633-a4pu6rlu	512	18	pig	pig	NN
cord-353633-a4pu6rlu	512	19	model	model	NN
cord-353633-a4pu6rlu	512	20	to	to	IN
cord-353633-a4pu6rlu	512	21	human	human	JJ
cord-353633-a4pu6rlu	512	22	study	study	NN
cord-353633-a4pu6rlu	512	23	Plasma	Plasma	NNP
cord-353633-a4pu6rlu	512	24	proteome	proteome	NN
cord-353633-a4pu6rlu	512	25	profiling	profiling	NN
cord-353633-a4pu6rlu	512	26	discovers	discover	VBZ
cord-353633-a4pu6rlu	512	27	novel	novel	NN
cord-353633-a4pu6rlu	512	28	proteins	protein	NNS
cord-353633-a4pu6rlu	512	29	associated	associate	VBN
cord-353633-a4pu6rlu	512	30	with	with	IN
cord-353633-a4pu6rlu	512	31	non	non	JJ
cord-353633-a4pu6rlu	512	32	-	-	JJ
cord-353633-a4pu6rlu	512	33	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	512	34	fatty	fatty	JJ
cord-353633-a4pu6rlu	512	35	liver	liver	NN
cord-353633-a4pu6rlu	512	36	disease	disease	NN
cord-353633-a4pu6rlu	512	37	Pharmacotherapy	Pharmacotherapy	NNP
cord-353633-a4pu6rlu	512	38	of	of	IN
cord-353633-a4pu6rlu	512	39	obesity	obesity	NN
cord-353633-a4pu6rlu	512	40	:	:	:
cord-353633-a4pu6rlu	513	1	Available	available	JJ
cord-353633-a4pu6rlu	513	2	medications	medication	NNS
cord-353633-a4pu6rlu	513	3	and	and	CC
cord-353633-a4pu6rlu	513	4	drugs	drug	NNS
cord-353633-a4pu6rlu	513	5	under	under	IN
cord-353633-a4pu6rlu	513	6	investigation	investigation	NN
cord-353633-a4pu6rlu	513	7	Obesity	obesity	NN
cord-353633-a4pu6rlu	513	8	as	as	IN
cord-353633-a4pu6rlu	513	9	a	a	DT
cord-353633-a4pu6rlu	513	10	Disease	Disease	NNP
cord-353633-a4pu6rlu	513	11	Pharmacotherapy	Pharmacotherapy	NNP
cord-353633-a4pu6rlu	513	12	of	of	IN
cord-353633-a4pu6rlu	513	13	type	type	NN
cord-353633-a4pu6rlu	513	14	2	2	CD
cord-353633-a4pu6rlu	513	15	diabetes	diabetes	NN
cord-353633-a4pu6rlu	513	16	:	:	:
cord-353633-a4pu6rlu	514	1	An	an	DT
cord-353633-a4pu6rlu	514	2	update	update	NN
cord-353633-a4pu6rlu	514	3	Current	current	JJ
cord-353633-a4pu6rlu	514	4	and	and	CC
cord-353633-a4pu6rlu	514	5	emerging	emerge	VBG
cord-353633-a4pu6rlu	514	6	pharmacological	pharmacological	JJ
cord-353633-a4pu6rlu	514	7	options	option	NNS
cord-353633-a4pu6rlu	514	8	for	for	IN
cord-353633-a4pu6rlu	514	9	the	the	DT
cord-353633-a4pu6rlu	514	10	treatment	treatment	NN
cord-353633-a4pu6rlu	514	11	of	of	IN
cord-353633-a4pu6rlu	514	12	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	514	13	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	514	14	Metabolic	metabolic	JJ
cord-353633-a4pu6rlu	514	15	regulation	regulation	NN
cord-353633-a4pu6rlu	514	16	of	of	IN
cord-353633-a4pu6rlu	514	17	activins	activin	NNS
cord-353633-a4pu6rlu	514	18	in	in	IN
cord-353633-a4pu6rlu	514	19	healthy	healthy	JJ
cord-353633-a4pu6rlu	514	20	individuals	individual	NNS
cord-353633-a4pu6rlu	514	21	and	and	CC
cord-353633-a4pu6rlu	514	22	in	in	IN
cord-353633-a4pu6rlu	514	23	obese	obese	JJ
cord-353633-a4pu6rlu	514	24	patients	patient	NNS
cord-353633-a4pu6rlu	514	25	undergoing	undergo	VBG
cord-353633-a4pu6rlu	514	26	bariatric	bariatric	JJ
cord-353633-a4pu6rlu	514	27	surgery	surgery	NN
cord-353633-a4pu6rlu	514	28	Non	non	JJ
cord-353633-a4pu6rlu	514	29	-	-	JJ
cord-353633-a4pu6rlu	514	30	invasive	invasive	JJ
cord-353633-a4pu6rlu	514	31	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	514	32	of	of	IN
cord-353633-a4pu6rlu	514	33	non	non	JJ
cord-353633-a4pu6rlu	514	34	-	-	JJ
cord-353633-a4pu6rlu	514	35	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	514	36	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	514	37	and	and	CC
cord-353633-a4pu6rlu	514	38	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	514	39	with	with	IN
cord-353633-a4pu6rlu	514	40	the	the	DT
cord-353633-a4pu6rlu	514	41	use	use	NN
cord-353633-a4pu6rlu	514	42	of	of	IN
cord-353633-a4pu6rlu	514	43	omics	omic	NNS
cord-353633-a4pu6rlu	514	44	and	and	CC
cord-353633-a4pu6rlu	514	45	supervised	supervise	VBN
cord-353633-a4pu6rlu	514	46	learning	learning	NN
cord-353633-a4pu6rlu	514	47	:	:	:
cord-353633-a4pu6rlu	514	48	A	a	DT
cord-353633-a4pu6rlu	514	49	proof	proof	NN
cord-353633-a4pu6rlu	514	50	of	of	IN
cord-353633-a4pu6rlu	514	51	concept	concept	NN
cord-353633-a4pu6rlu	514	52	study	study	NN
cord-353633-a4pu6rlu	514	53	Circulating	circulate	VBG
cord-353633-a4pu6rlu	514	54	levels	level	NNS
cord-353633-a4pu6rlu	514	55	of	of	IN
cord-353633-a4pu6rlu	514	56	gastrointestinal	gastrointestinal	JJ
cord-353633-a4pu6rlu	514	57	hormones	hormone	NNS
cord-353633-a4pu6rlu	514	58	in	in	IN
cord-353633-a4pu6rlu	514	59	response	response	NN
cord-353633-a4pu6rlu	514	60	to	to	IN
cord-353633-a4pu6rlu	514	61	the	the	DT
cord-353633-a4pu6rlu	514	62	most	most	RBS
cord-353633-a4pu6rlu	514	63	common	common	JJ
cord-353633-a4pu6rlu	514	64	types	type	NNS
cord-353633-a4pu6rlu	514	65	of	of	IN
cord-353633-a4pu6rlu	514	66	bariatric	bariatric	JJ
cord-353633-a4pu6rlu	514	67	surgery	surgery	NN
cord-353633-a4pu6rlu	514	68	and	and	CC
cord-353633-a4pu6rlu	514	69	predictive	predictive	JJ
cord-353633-a4pu6rlu	514	70	value	value	NN
cord-353633-a4pu6rlu	514	71	for	for	IN
cord-353633-a4pu6rlu	514	72	weight	weight	NN
cord-353633-a4pu6rlu	514	73	loss	loss	NN
cord-353633-a4pu6rlu	514	74	over	over	IN
cord-353633-a4pu6rlu	514	75	one	one	CD
cord-353633-a4pu6rlu	514	76	year	year	NN
cord-353633-a4pu6rlu	514	77	:	:	:
cord-353633-a4pu6rlu	514	78	Evidence	evidence	NN
cord-353633-a4pu6rlu	514	79	from	from	IN
cord-353633-a4pu6rlu	514	80	two	two	CD
cord-353633-a4pu6rlu	514	81	independent	independent	JJ
cord-353633-a4pu6rlu	514	82	trials	trial	NNS
cord-353633-a4pu6rlu	514	83	Shortterm	shortterm	JJ
cord-353633-a4pu6rlu	514	84	treatment	treatment	NN
cord-353633-a4pu6rlu	514	85	with	with	IN
cord-353633-a4pu6rlu	514	86	high	high	JJ
cord-353633-a4pu6rlu	514	87	dose	dose	NN
cord-353633-a4pu6rlu	514	88	liraglutide	liraglutide	NN
cord-353633-a4pu6rlu	514	89	improves	improve	VBZ
cord-353633-a4pu6rlu	514	90	lipid	lipid	NN
cord-353633-a4pu6rlu	514	91	and	and	CC
cord-353633-a4pu6rlu	514	92	lipoprotein	lipoprotein	NN
cord-353633-a4pu6rlu	514	93	profile	profile	NN
cord-353633-a4pu6rlu	514	94	and	and	CC
cord-353633-a4pu6rlu	514	95	changes	change	VBZ
cord-353633-a4pu6rlu	514	96	hormonal	hormonal	JJ
cord-353633-a4pu6rlu	514	97	mediators	mediator	NNS
cord-353633-a4pu6rlu	514	98	of	of	IN
cord-353633-a4pu6rlu	514	99	lipid	lipid	NN
cord-353633-a4pu6rlu	514	100	metabolism	metabolism	NN
cord-353633-a4pu6rlu	514	101	in	in	IN
cord-353633-a4pu6rlu	514	102	obese	obese	JJ
cord-353633-a4pu6rlu	514	103	patients	patient	NNS
cord-353633-a4pu6rlu	514	104	with	with	IN
cord-353633-a4pu6rlu	514	105	no	no	DT
cord-353633-a4pu6rlu	514	106	overt	overt	JJ
cord-353633-a4pu6rlu	514	107	type	type	NN
cord-353633-a4pu6rlu	514	108	2	2	CD
cord-353633-a4pu6rlu	514	109	diabetes	diabetes	NN
cord-353633-a4pu6rlu	514	110	mellitus	mellitus	NN
cord-353633-a4pu6rlu	514	111	:	:	:
cord-353633-a4pu6rlu	514	112	a	a	DT
cord-353633-a4pu6rlu	514	113	randomized	randomized	JJ
cord-353633-a4pu6rlu	514	114	,	,	,
cord-353633-a4pu6rlu	514	115	placebo	placebo	NN
cord-353633-a4pu6rlu	514	116	-	-	HYPH
cord-353633-a4pu6rlu	514	117	controlled	control	VBN
cord-353633-a4pu6rlu	514	118	,	,	,
cord-353633-a4pu6rlu	514	119	cross	cross	NN
cord-353633-a4pu6rlu	514	120	-	-	HYPH
cord-353633-a4pu6rlu	514	121	over	over	RP
cord-353633-a4pu6rlu	514	122	,	,	,
cord-353633-a4pu6rlu	514	123	double	double	JJ
cord-353633-a4pu6rlu	514	124	-	-	HYPH
cord-353633-a4pu6rlu	514	125	blind	blind	JJ
cord-353633-a4pu6rlu	514	126	clinical	clinical	JJ
cord-353633-a4pu6rlu	514	127	trial	trial	NN
cord-353633-a4pu6rlu	514	128	Circulating	circulate	VBG
cord-353633-a4pu6rlu	514	129	levels	level	NNS
cord-353633-a4pu6rlu	514	130	of	of	IN
cord-353633-a4pu6rlu	514	131	the	the	DT
cord-353633-a4pu6rlu	514	132	components	component	NNS
cord-353633-a4pu6rlu	514	133	of	of	IN
cord-353633-a4pu6rlu	514	134	the	the	DT
cord-353633-a4pu6rlu	514	135	GH	GH	NNP
cord-353633-a4pu6rlu	514	136	/	/	SYM
cord-353633-a4pu6rlu	514	137	IGF-1	IGF-1	NNP
cord-353633-a4pu6rlu	514	138	/	/	SYM
cord-353633-a4pu6rlu	514	139	IGFBPs	IGFBPs	NNP
cord-353633-a4pu6rlu	514	140	axis	axis	NN
cord-353633-a4pu6rlu	514	141	total	total	JJ
cord-353633-a4pu6rlu	514	142	and	and	CC
cord-353633-a4pu6rlu	514	143	intact	intact	JJ
cord-353633-a4pu6rlu	514	144	IGF	IGF	NNP
cord-353633-a4pu6rlu	514	145	-	-	HYPH
cord-353633-a4pu6rlu	514	146	binding	bind	VBG
cord-353633-a4pu6rlu	514	147	proteins	protein	NNS
cord-353633-a4pu6rlu	514	148	(	(	-LRB-
cord-353633-a4pu6rlu	514	149	IGFBP	IGFBP	NNP
cord-353633-a4pu6rlu	514	150	)	)	-RRB-
cord-353633-a4pu6rlu	515	1	3	3	CD
cord-353633-a4pu6rlu	515	2	and	and	CC
cord-353633-a4pu6rlu	515	3	IGFBP	IGFBP	NNP
cord-353633-a4pu6rlu	515	4	4	4	CD
cord-353633-a4pu6rlu	515	5	and	and	CC
cord-353633-a4pu6rlu	515	6	total	total	JJ
cord-353633-a4pu6rlu	515	7	IGFBP	IGFBP	NNP
cord-353633-a4pu6rlu	515	8	5	5	CD
cord-353633-a4pu6rlu	515	9	,	,	,
cord-353633-a4pu6rlu	515	10	as	as	RB
cord-353633-a4pu6rlu	515	11	well	well	RB
cord-353633-a4pu6rlu	515	12	as	as	IN
cord-353633-a4pu6rlu	515	13	PAPPA	PAPPA	NNP
cord-353633-a4pu6rlu	515	14	,	,	,
cord-353633-a4pu6rlu	515	15	PAPPA2	PAPPA2	NNP
cord-353633-a4pu6rlu	516	1	and	and	CC
cord-353633-a4pu6rlu	516	2	Stanniocalcin-2	Stanniocalcin-2	NNPS
cord-353633-a4pu6rlu	516	3	levels	level	NNS
cord-353633-a4pu6rlu	516	4	are	be	VBP
cord-353633-a4pu6rlu	516	5	not	not	RB
cord-353633-a4pu6rlu	516	6	altered	alter	VBN
cord-353633-a4pu6rlu	516	7	in	in	IN
cord-353633-a4pu6rlu	516	8	response	response	NN
cord-353633-a4pu6rlu	516	9	to	to	IN
cord-353633-a4pu6rlu	516	10	energy	energy	NN
cord-353633-a4pu6rlu	516	11	deprivation	deprivation	NN
cord-353633-a4pu6rlu	516	12	and/or	and/or	CC
cord-353633-a4pu6rlu	516	13	metreleptin	metreleptin	NNP
cord-353633-a4pu6rlu	516	14	administration	administration	NN
cord-353633-a4pu6rlu	516	15	in	in	IN
cord-353633-a4pu6rlu	516	16	humans	human	NNS
cord-353633-a4pu6rlu	516	17	Free	Free	NNP
cord-353633-a4pu6rlu	516	18	IGF-1	IGF-1	NNP
cord-353633-a4pu6rlu	516	19	,	,	,
cord-353633-a4pu6rlu	516	20	Intact	Intact	NNP
cord-353633-a4pu6rlu	516	21	IGFBP-4	IGFBP-4	NNP
cord-353633-a4pu6rlu	516	22	,	,	,
cord-353633-a4pu6rlu	516	23	and	and	CC
cord-353633-a4pu6rlu	517	1	PicoPAPP	PicoPAPP	NNP
cord-353633-a4pu6rlu	517	2	-	-	HYPH
cord-353633-a4pu6rlu	517	3	A	A	NNP
cord-353633-a4pu6rlu	517	4	are	be	VBP
cord-353633-a4pu6rlu	517	5	Altered	alter	VBN
cord-353633-a4pu6rlu	517	6	in	in	IN
cord-353633-a4pu6rlu	517	7	Acute	acute	JJ
cord-353633-a4pu6rlu	517	8	Myocardial	Myocardial	NNP
cord-353633-a4pu6rlu	517	9	Infarction	Infarction	NNP
cord-353633-a4pu6rlu	517	10	Compared	compare	VBN
cord-353633-a4pu6rlu	517	11	to	to	IN
cord-353633-a4pu6rlu	517	12	Stable	stable	JJ
cord-353633-a4pu6rlu	517	13	Coronary	coronary	JJ
cord-353633-a4pu6rlu	517	14	Artery	Artery	NNP
cord-353633-a4pu6rlu	517	15	Disease	Disease	NNP
cord-353633-a4pu6rlu	517	16	and	and	CC
cord-353633-a4pu6rlu	517	17	Healthy	Healthy	NNP
cord-353633-a4pu6rlu	517	18	Controls	Controls	NNP
cord-353633-a4pu6rlu	517	19	Follistatins	Follistatins	NNP
cord-353633-a4pu6rlu	517	20	in	in	IN
cord-353633-a4pu6rlu	517	21	glucose	glucose	NN
cord-353633-a4pu6rlu	517	22	regulation	regulation	NN
cord-353633-a4pu6rlu	517	23	in	in	IN
cord-353633-a4pu6rlu	517	24	healthy	healthy	JJ
cord-353633-a4pu6rlu	517	25	and	and	CC
cord-353633-a4pu6rlu	517	26	obese	obese	JJ
cord-353633-a4pu6rlu	517	27	individuals	individual	NNS
cord-353633-a4pu6rlu	517	28	Physiology	Physiology	NNP
cord-353633-a4pu6rlu	517	29	of	of	IN
cord-353633-a4pu6rlu	517	30	Activins	Activins	NNP
cord-353633-a4pu6rlu	517	31	/	/	SYM
cord-353633-a4pu6rlu	517	32	Follistatins	Follistatins	NNP
cord-353633-a4pu6rlu	517	33	:	:	:
cord-353633-a4pu6rlu	518	1	Associations	association	NNS
cord-353633-a4pu6rlu	518	2	With	with	IN
cord-353633-a4pu6rlu	518	3	Metabolic	Metabolic	NNP
cord-353633-a4pu6rlu	518	4	and	and	CC
cord-353633-a4pu6rlu	518	5	Anthropometric	anthropometric	JJ
cord-353633-a4pu6rlu	518	6	Variables	Variables	NNPS
cord-353633-a4pu6rlu	518	7	and	and	CC
cord-353633-a4pu6rlu	518	8	Response	response	NN
cord-353633-a4pu6rlu	518	9	to	to	IN
cord-353633-a4pu6rlu	518	10	Exercise	Exercise	NNP
cord-353633-a4pu6rlu	518	11	Regulation	regulation	NN
cord-353633-a4pu6rlu	518	12	of	of	IN
cord-353633-a4pu6rlu	518	13	the	the	DT
cord-353633-a4pu6rlu	518	14	activins	activins	NNP
cord-353633-a4pu6rlu	518	15	-	-	HYPH
cord-353633-a4pu6rlu	518	16	follistatins	follistatin	NNS
cord-353633-a4pu6rlu	518	17	-	-	HYPH
cord-353633-a4pu6rlu	518	18	inhibins	inhibin	NNS
cord-353633-a4pu6rlu	518	19	axis	axis	NN
cord-353633-a4pu6rlu	518	20	by	by	IN
cord-353633-a4pu6rlu	518	21	energy	energy	NN
cord-353633-a4pu6rlu	518	22	status	status	NN
cord-353633-a4pu6rlu	518	23	:	:	:
cord-353633-a4pu6rlu	518	24	Impact	impact	NN
cord-353633-a4pu6rlu	518	25	on	on	IN
cord-353633-a4pu6rlu	518	26	reproductive	reproductive	JJ
cord-353633-a4pu6rlu	518	27	function	function	NN
cord-353633-a4pu6rlu	518	28	Association	Association	NNP
cord-353633-a4pu6rlu	518	29	of	of	IN
cord-353633-a4pu6rlu	518	30	Adipokines	Adipokines	NNPS
cord-353633-a4pu6rlu	518	31	with	with	IN
cord-353633-a4pu6rlu	518	32	Development	Development	NNP
cord-353633-a4pu6rlu	518	33	and	and	CC
cord-353633-a4pu6rlu	518	34	Progression	Progression	NNP
cord-353633-a4pu6rlu	518	35	of	of	IN
cord-353633-a4pu6rlu	518	36	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	518	37	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	518	38	Liver	Liver	NNP
cord-353633-a4pu6rlu	518	39	Disease	Disease	NNP
cord-353633-a4pu6rlu	519	1	Adiponectin	Adiponectin	NNP
cord-353633-a4pu6rlu	519	2	administration	administration	NN
cord-353633-a4pu6rlu	519	3	prevents	prevent	VBZ
cord-353633-a4pu6rlu	519	4	weight	weight	NN
cord-353633-a4pu6rlu	519	5	gain	gain	NN
cord-353633-a4pu6rlu	519	6	and	and	CC
cord-353633-a4pu6rlu	519	7	glycemic	glycemic	NN
cord-353633-a4pu6rlu	519	8	profile	profile	NN
cord-353633-a4pu6rlu	519	9	changes	change	NNS
cord-353633-a4pu6rlu	519	10	in	in	IN
cord-353633-a4pu6rlu	519	11	diet	diet	NN
cord-353633-a4pu6rlu	519	12	-	-	HYPH
cord-353633-a4pu6rlu	519	13	induced	induce	VBN
cord-353633-a4pu6rlu	519	14	obese	obese	JJ
cord-353633-a4pu6rlu	519	15	immune	immune	JJ
cord-353633-a4pu6rlu	519	16	deficient	deficient	JJ
cord-353633-a4pu6rlu	519	17	Rag1-/-mice	rag1-/-mice	NN
cord-353633-a4pu6rlu	519	18	lacking	lack	VBG
cord-353633-a4pu6rlu	519	19	mature	mature	JJ
cord-353633-a4pu6rlu	519	20	lymphocytes	lymphocyte	NNS
cord-353633-a4pu6rlu	520	1	The	the	DT
cord-353633-a4pu6rlu	520	2	Role	role	NN
cord-353633-a4pu6rlu	520	3	of	of	IN
cord-353633-a4pu6rlu	520	4	Glicentin	Glicentin	NNP
cord-353633-a4pu6rlu	520	5	and	and	CC
cord-353633-a4pu6rlu	520	6	Oxyntomodulin	Oxyntomodulin	NNP
cord-353633-a4pu6rlu	520	7	in	in	IN
cord-353633-a4pu6rlu	520	8	Human	Human	NNP
cord-353633-a4pu6rlu	520	9	Metabolism	Metabolism	NNP
cord-353633-a4pu6rlu	520	10	:	:	:
cord-353633-a4pu6rlu	520	11	New	new	JJ
cord-353633-a4pu6rlu	520	12	Evidence	evidence	NN
cord-353633-a4pu6rlu	520	13	and	and	CC
cord-353633-a4pu6rlu	520	14	New	New	NNP
cord-353633-a4pu6rlu	520	15	Directions	Directions	NNP
cord-353633-a4pu6rlu	520	16	Quantitative	Quantitative	NNP
cord-353633-a4pu6rlu	520	17	Proteomics	Proteomics	NNPS
cord-353633-a4pu6rlu	520	18	and	and	CC
cord-353633-a4pu6rlu	520	19	Mechanistic	Mechanistic	NNP
cord-353633-a4pu6rlu	520	20	Modeling	Modeling	NNP
cord-353633-a4pu6rlu	520	21	of	of	IN
cord-353633-a4pu6rlu	520	22	Transporter	transporter	NN
cord-353633-a4pu6rlu	520	23	-	-	HYPH
cord-353633-a4pu6rlu	520	24	Mediated	mediate	VBN
cord-353633-a4pu6rlu	520	25	Disposition	Disposition	NNP
cord-353633-a4pu6rlu	520	26	in	in	IN
cord-353633-a4pu6rlu	520	27	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	520	28	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	520	29	Liver	Liver	NNP
cord-353633-a4pu6rlu	520	30	Disease	Disease	NNP
cord-353633-a4pu6rlu	520	31	Gut	Gut	NNP
cord-353633-a4pu6rlu	520	32	microbial	microbial	JJ
cord-353633-a4pu6rlu	520	33	metabolites	metabolite	NNS
cord-353633-a4pu6rlu	520	34	in	in	IN
cord-353633-a4pu6rlu	520	35	obesity	obesity	NN
cord-353633-a4pu6rlu	520	36	,	,	,
cord-353633-a4pu6rlu	520	37	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	520	38	and	and	CC
cord-353633-a4pu6rlu	520	39	T2DM	T2DM	NNP
cord-353633-a4pu6rlu	520	40	Bile	bile	NN
cord-353633-a4pu6rlu	520	41	acids	acid	NNS
cord-353633-a4pu6rlu	520	42	and	and	CC
cord-353633-a4pu6rlu	520	43	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	520	44	fatty	fatty	JJ
cord-353633-a4pu6rlu	520	45	liver	liver	NN
cord-353633-a4pu6rlu	520	46	disease	disease	NN
cord-353633-a4pu6rlu	520	47	:	:	:
cord-353633-a4pu6rlu	521	1	Molecular	molecular	JJ
cord-353633-a4pu6rlu	521	2	insights	insight	NNS
cord-353633-a4pu6rlu	521	3	and	and	CC
cord-353633-a4pu6rlu	521	4	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	521	5	perspectives	perspective	NNS
cord-353633-a4pu6rlu	521	6	Sources	source	NNS
cord-353633-a4pu6rlu	521	7	of	of	IN
cord-353633-a4pu6rlu	521	8	fatty	fatty	JJ
cord-353633-a4pu6rlu	521	9	acids	acid	NNS
cord-353633-a4pu6rlu	521	10	stored	store	VBN
cord-353633-a4pu6rlu	521	11	in	in	IN
cord-353633-a4pu6rlu	521	12	liver	liver	NN
cord-353633-a4pu6rlu	521	13	and	and	CC
cord-353633-a4pu6rlu	521	14	secreted	secrete	VBN
cord-353633-a4pu6rlu	521	15	via	via	IN
cord-353633-a4pu6rlu	521	16	lipoproteins	lipoprotein	NNS
cord-353633-a4pu6rlu	521	17	in	in	IN
cord-353633-a4pu6rlu	521	18	patients	patient	NNS
cord-353633-a4pu6rlu	521	19	with	with	IN
cord-353633-a4pu6rlu	521	20	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	521	21	fatty	fatty	JJ
cord-353633-a4pu6rlu	521	22	liver	liver	NN
cord-353633-a4pu6rlu	521	23	disease	disease	NN
cord-353633-a4pu6rlu	522	1	A	a	DT
cord-353633-a4pu6rlu	522	2	lipidomic	lipidomic	JJ
cord-353633-a4pu6rlu	522	3	analysis	analysis	NN
cord-353633-a4pu6rlu	522	4	of	of	IN
cord-353633-a4pu6rlu	522	5	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	522	6	fatty	fatty	JJ
cord-353633-a4pu6rlu	522	7	liver	liver	NN
cord-353633-a4pu6rlu	522	8	disease	disease	NN
cord-353633-a4pu6rlu	523	1	The	the	DT
cord-353633-a4pu6rlu	523	2	plasma	plasma	NN
cord-353633-a4pu6rlu	523	3	lipidomic	lipidomic	JJ
cord-353633-a4pu6rlu	523	4	signature	signature	NN
cord-353633-a4pu6rlu	523	5	of	of	IN
cord-353633-a4pu6rlu	523	6	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	523	7	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	523	8	Biomarkers	Biomarkers	NNPS
cord-353633-a4pu6rlu	523	9	of	of	IN
cord-353633-a4pu6rlu	523	10	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	523	11	progression	progression	NN
cord-353633-a4pu6rlu	523	12	:	:	:
cord-353633-a4pu6rlu	523	13	a	a	DT
cord-353633-a4pu6rlu	523	14	lipidomics	lipidomic	NNS
cord-353633-a4pu6rlu	523	15	approach	approach	NN
cord-353633-a4pu6rlu	523	16	to	to	IN
cord-353633-a4pu6rlu	523	17	an	an	DT
cord-353633-a4pu6rlu	523	18	epidemic	epidemic	NN
cord-353633-a4pu6rlu	524	1	Hepatic	hepatic	JJ
cord-353633-a4pu6rlu	524	2	and	and	CC
cord-353633-a4pu6rlu	524	3	serum	serum	NN
cord-353633-a4pu6rlu	524	4	lipid	lipid	NN
cord-353633-a4pu6rlu	524	5	signatures	signature	NNS
cord-353633-a4pu6rlu	524	6	specific	specific	JJ
cord-353633-a4pu6rlu	524	7	to	to	IN
cord-353633-a4pu6rlu	524	8	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	524	9	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	524	10	in	in	IN
cord-353633-a4pu6rlu	524	11	murine	murine	JJ
cord-353633-a4pu6rlu	524	12	models	model	NNS
cord-353633-a4pu6rlu	525	1	Metabolism	metabolism	NN
cord-353633-a4pu6rlu	525	2	dysregulation	dysregulation	NN
cord-353633-a4pu6rlu	525	3	induces	induce	VBZ
cord-353633-a4pu6rlu	525	4	a	a	DT
cord-353633-a4pu6rlu	525	5	specific	specific	JJ
cord-353633-a4pu6rlu	525	6	lipid	lipid	NN
cord-353633-a4pu6rlu	525	7	signature	signature	NN
cord-353633-a4pu6rlu	525	8	of	of	IN
cord-353633-a4pu6rlu	525	9	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	525	10	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	525	11	in	in	IN
cord-353633-a4pu6rlu	525	12	patients	patient	NNS
cord-353633-a4pu6rlu	525	13	Bioactive	Bioactive	NNP
cord-353633-a4pu6rlu	525	14	Lipid	Lipid	NNP
cord-353633-a4pu6rlu	525	15	Species	Species	NNPS
cord-353633-a4pu6rlu	525	16	and	and	CC
cord-353633-a4pu6rlu	525	17	Metabolic	metabolic	JJ
cord-353633-a4pu6rlu	525	18	Pathways	Pathways	NNPS
cord-353633-a4pu6rlu	525	19	in	in	IN
cord-353633-a4pu6rlu	525	20	Progression	Progression	NNP
cord-353633-a4pu6rlu	525	21	and	and	CC
cord-353633-a4pu6rlu	525	22	Resolution	Resolution	NNP
cord-353633-a4pu6rlu	525	23	of	of	IN
cord-353633-a4pu6rlu	525	24	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	525	25	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	525	26	Non	Non	NNP
cord-353633-a4pu6rlu	525	27	-	-	JJ
cord-353633-a4pu6rlu	525	28	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	525	29	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	525	30	:	:	:
cord-353633-a4pu6rlu	525	31	emerging	emerge	VBG
cord-353633-a4pu6rlu	525	32	molecular	molecular	JJ
cord-353633-a4pu6rlu	525	33	targets	target	NNS
cord-353633-a4pu6rlu	525	34	and	and	CC
cord-353633-a4pu6rlu	525	35	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	525	36	strategies	strategy	NNS
cord-353633-a4pu6rlu	525	37	New	new	JJ
cord-353633-a4pu6rlu	525	38	insights	insight	NNS
cord-353633-a4pu6rlu	525	39	into	into	IN
cord-353633-a4pu6rlu	525	40	the	the	DT
cord-353633-a4pu6rlu	525	41	role	role	NN
cord-353633-a4pu6rlu	525	42	and	and	CC
cord-353633-a4pu6rlu	525	43	mechanism	mechanism	NN
cord-353633-a4pu6rlu	525	44	of	of	IN
cord-353633-a4pu6rlu	525	45	c	c	NNP
cord-353633-a4pu6rlu	525	46	-	-	:
cord-353633-a4pu6rlu	525	47	Jun	Jun	NNP
cord-353633-a4pu6rlu	525	48	-	-	HYPH
cord-353633-a4pu6rlu	525	49	N	N	NNP
cord-353633-a4pu6rlu	525	50	-	-	HYPH
cord-353633-a4pu6rlu	525	51	terminal	terminal	NN
cord-353633-a4pu6rlu	525	52	kinase	kinase	NN
cord-353633-a4pu6rlu	525	53	signaling	signal	VBG
cord-353633-a4pu6rlu	525	54	in	in	IN
cord-353633-a4pu6rlu	525	55	the	the	DT
cord-353633-a4pu6rlu	525	56	pathobiology	pathobiology	NN
cord-353633-a4pu6rlu	525	57	of	of	IN
cord-353633-a4pu6rlu	525	58	liver	liver	NN
cord-353633-a4pu6rlu	525	59	diseases	disease	NNS
cord-353633-a4pu6rlu	525	60	Effect	effect	NN
cord-353633-a4pu6rlu	525	61	of	of	IN
cord-353633-a4pu6rlu	525	62	modulation	modulation	NN
cord-353633-a4pu6rlu	525	63	of	of	IN
cord-353633-a4pu6rlu	525	64	PPAR	PPAR	NNP
cord-353633-a4pu6rlu	525	65	-	-	HYPH
cord-353633-a4pu6rlu	525	66	gamma	gamma	NN
cord-353633-a4pu6rlu	525	67	activity	activity	NN
cord-353633-a4pu6rlu	525	68	on	on	IN
cord-353633-a4pu6rlu	525	69	Kupffer	Kupffer	NNP
cord-353633-a4pu6rlu	525	70	cells	cell	NNS
cord-353633-a4pu6rlu	525	71	M1	M1	NNP
cord-353633-a4pu6rlu	525	72	/	/	SYM
cord-353633-a4pu6rlu	525	73	M2	m2	JJ
cord-353633-a4pu6rlu	525	74	polarization	polarization	NN
cord-353633-a4pu6rlu	525	75	in	in	IN
cord-353633-a4pu6rlu	525	76	the	the	DT
cord-353633-a4pu6rlu	525	77	development	development	NN
cord-353633-a4pu6rlu	525	78	of	of	IN
cord-353633-a4pu6rlu	525	79	non	non	JJ
cord-353633-a4pu6rlu	525	80	-	-	JJ
cord-353633-a4pu6rlu	525	81	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	525	82	fatty	fatty	JJ
cord-353633-a4pu6rlu	525	83	liver	liver	NN
cord-353633-a4pu6rlu	525	84	disease	disease	NN
cord-353633-a4pu6rlu	525	85	Micromolar	Micromolar	NNP
cord-353633-a4pu6rlu	525	86	changes	change	VBZ
cord-353633-a4pu6rlu	525	87	in	in	IN
cord-353633-a4pu6rlu	525	88	lysophosphatidylcholine	lysophosphatidylcholine	JJ
cord-353633-a4pu6rlu	525	89	concentration	concentration	NN
cord-353633-a4pu6rlu	525	90	cause	cause	VBP
cord-353633-a4pu6rlu	525	91	minor	minor	JJ
cord-353633-a4pu6rlu	525	92	effects	effect	NNS
cord-353633-a4pu6rlu	525	93	on	on	IN
cord-353633-a4pu6rlu	525	94	mitochondrial	mitochondrial	JJ
cord-353633-a4pu6rlu	525	95	permeability	permeability	NN
cord-353633-a4pu6rlu	525	96	but	but	CC
cord-353633-a4pu6rlu	525	97	major	major	JJ
cord-353633-a4pu6rlu	525	98	alterations	alteration	NNS
cord-353633-a4pu6rlu	525	99	in	in	IN
cord-353633-a4pu6rlu	525	100	function	function	NN
cord-353633-a4pu6rlu	526	1	Lipid	lipid	NN
cord-353633-a4pu6rlu	526	2	-	-	HYPH
cord-353633-a4pu6rlu	526	3	Induced	induce	VBN
cord-353633-a4pu6rlu	526	4	Signaling	signaling	NN
cord-353633-a4pu6rlu	526	5	Causes	cause	VBZ
cord-353633-a4pu6rlu	526	6	Release	Release	NNP
cord-353633-a4pu6rlu	526	7	of	of	IN
cord-353633-a4pu6rlu	526	8	Inflammatory	Inflammatory	NNP
cord-353633-a4pu6rlu	526	9	Extracellular	Extracellular	NNP
cord-353633-a4pu6rlu	526	10	Vesicles	Vesicles	NNP
cord-353633-a4pu6rlu	526	11	From	from	IN
cord-353633-a4pu6rlu	526	12	Hepatocytes	Hepatocytes	NNP
cord-353633-a4pu6rlu	527	1	The	the	DT
cord-353633-a4pu6rlu	527	2	ratio	ratio	NN
cord-353633-a4pu6rlu	527	3	of	of	IN
cord-353633-a4pu6rlu	527	4	phosphatidylcholine	phosphatidylcholine	NN
cord-353633-a4pu6rlu	527	5	to	to	IN
cord-353633-a4pu6rlu	527	6	phosphatidylethanolamine	phosphatidylethanolamine	JJ
cord-353633-a4pu6rlu	527	7	influences	influence	NNS
cord-353633-a4pu6rlu	527	8	membrane	membrane	NN
cord-353633-a4pu6rlu	527	9	integrity	integrity	NN
cord-353633-a4pu6rlu	527	10	and	and	CC
cord-353633-a4pu6rlu	528	1	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	528	2	Hepatocyte	Hepatocyte	NNP
cord-353633-a4pu6rlu	528	3	autotaxin	autotaxin	JJ
cord-353633-a4pu6rlu	528	4	expression	expression	NN
cord-353633-a4pu6rlu	528	5	promotes	promote	VBZ
cord-353633-a4pu6rlu	528	6	liver	liver	NN
cord-353633-a4pu6rlu	528	7	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	528	8	and	and	CC
cord-353633-a4pu6rlu	528	9	cancer	cancer	NN
cord-353633-a4pu6rlu	528	10	Lipid	Lipid	NNP
cord-353633-a4pu6rlu	528	11	-	-	HYPH
cord-353633-a4pu6rlu	528	12	induced	induce	VBN
cord-353633-a4pu6rlu	528	13	insulin	insulin	NN
cord-353633-a4pu6rlu	528	14	resistance	resistance	NN
cord-353633-a4pu6rlu	528	15	mediated	mediate	VBN
cord-353633-a4pu6rlu	528	16	by	by	IN
cord-353633-a4pu6rlu	528	17	the	the	DT
cord-353633-a4pu6rlu	528	18	proinflammatory	proinflammatory	JJ
cord-353633-a4pu6rlu	528	19	receptor	receptor	NN
cord-353633-a4pu6rlu	528	20	TLR4	TLR4	NNP
cord-353633-a4pu6rlu	528	21	requires	require	VBZ
cord-353633-a4pu6rlu	528	22	saturated	saturate	VBN
cord-353633-a4pu6rlu	528	23	fatty	fatty	JJ
cord-353633-a4pu6rlu	528	24	acid	acid	NN
cord-353633-a4pu6rlu	528	25	-	-	HYPH
cord-353633-a4pu6rlu	528	26	induced	induce	VBN
cord-353633-a4pu6rlu	528	27	ceramide	ceramide	NN
cord-353633-a4pu6rlu	528	28	biosynthesis	biosynthesis	NN
cord-353633-a4pu6rlu	528	29	in	in	IN
cord-353633-a4pu6rlu	528	30	mice	mouse	NNS
cord-353633-a4pu6rlu	529	1	CerS2	CerS2	NNP
cord-353633-a4pu6rlu	529	2	haploinsufficiency	haploinsufficiency	NN
cord-353633-a4pu6rlu	529	3	inhibits	inhibit	VBZ
cord-353633-a4pu6rlu	529	4	beta	beta	NN
cord-353633-a4pu6rlu	529	5	-	-	HYPH
cord-353633-a4pu6rlu	529	6	oxidation	oxidation	NN
cord-353633-a4pu6rlu	529	7	and	and	CC
cord-353633-a4pu6rlu	529	8	confers	confer	VBZ
cord-353633-a4pu6rlu	529	9	susceptibility	susceptibility	NN
cord-353633-a4pu6rlu	529	10	to	to	IN
cord-353633-a4pu6rlu	529	11	diet	diet	NN
cord-353633-a4pu6rlu	529	12	-	-	HYPH
cord-353633-a4pu6rlu	529	13	induced	induce	VBN
cord-353633-a4pu6rlu	529	14	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	529	15	and	and	CC
cord-353633-a4pu6rlu	529	16	insulin	insulin	NN
cord-353633-a4pu6rlu	529	17	resistance	resistance	NN
cord-353633-a4pu6rlu	529	18	Obesity	obesity	NN
cord-353633-a4pu6rlu	529	19	-	-	HYPH
cord-353633-a4pu6rlu	529	20	induced	induce	VBN
cord-353633-a4pu6rlu	529	21	CerS6-dependent	cers6-dependent	NN
cord-353633-a4pu6rlu	529	22	C16:0	C16:0	NNP
cord-353633-a4pu6rlu	529	23	ceramide	ceramide	NN
cord-353633-a4pu6rlu	529	24	production	production	NN
cord-353633-a4pu6rlu	529	25	promotes	promote	VBZ
cord-353633-a4pu6rlu	529	26	weight	weight	NN
cord-353633-a4pu6rlu	529	27	gain	gain	NN
cord-353633-a4pu6rlu	529	28	and	and	CC
cord-353633-a4pu6rlu	529	29	glucose	glucose	NN
cord-353633-a4pu6rlu	529	30	intolerance	intolerance	NN
cord-353633-a4pu6rlu	529	31	Hepatic	hepatic	NN
cord-353633-a4pu6rlu	529	32	cannabinoid-1	cannabinoid-1	NNP
cord-353633-a4pu6rlu	529	33	receptors	receptor	NNS
cord-353633-a4pu6rlu	529	34	mediate	mediate	VBP
cord-353633-a4pu6rlu	529	35	diet	diet	NN
cord-353633-a4pu6rlu	529	36	-	-	HYPH
cord-353633-a4pu6rlu	529	37	induced	induce	VBN
cord-353633-a4pu6rlu	529	38	insulin	insulin	NN
cord-353633-a4pu6rlu	529	39	resistance	resistance	NN
cord-353633-a4pu6rlu	529	40	by	by	IN
cord-353633-a4pu6rlu	529	41	increasing	increase	VBG
cord-353633-a4pu6rlu	529	42	de	de	FW
cord-353633-a4pu6rlu	529	43	novo	novo	NNP
cord-353633-a4pu6rlu	529	44	synthesis	synthesis	NN
cord-353633-a4pu6rlu	529	45	of	of	IN
cord-353633-a4pu6rlu	529	46	long	long	JJ
cord-353633-a4pu6rlu	529	47	-	-	HYPH
cord-353633-a4pu6rlu	529	48	chain	chain	NN
cord-353633-a4pu6rlu	529	49	ceramides	ceramide	NNS
cord-353633-a4pu6rlu	530	1	Acidic	acidic	JJ
cord-353633-a4pu6rlu	530	2	sphingomyelinase	sphingomyelinase	NN
cord-353633-a4pu6rlu	530	3	controls	control	VBZ
cord-353633-a4pu6rlu	530	4	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	530	5	stellate	stellate	JJ
cord-353633-a4pu6rlu	530	6	cell	cell	NN
cord-353633-a4pu6rlu	530	7	activation	activation	NN
cord-353633-a4pu6rlu	530	8	and	and	CC
cord-353633-a4pu6rlu	530	9	in	in	IN
cord-353633-a4pu6rlu	530	10	vivo	vivo	NN
cord-353633-a4pu6rlu	530	11	liver	liver	NN
cord-353633-a4pu6rlu	531	1	fibrogenesis	fibrogenesis	NNP
cord-353633-a4pu6rlu	531	2	Biosynthesis	Biosynthesis	NNP
cord-353633-a4pu6rlu	531	3	and	and	CC
cord-353633-a4pu6rlu	531	4	bioavailability	bioavailability	NN
cord-353633-a4pu6rlu	531	5	of	of	IN
cord-353633-a4pu6rlu	531	6	long	long	JJ
cord-353633-a4pu6rlu	531	7	-	-	HYPH
cord-353633-a4pu6rlu	531	8	chain	chain	NN
cord-353633-a4pu6rlu	531	9	polyunsaturated	polyunsaturated	JJ
cord-353633-a4pu6rlu	531	10	fatty	fatty	JJ
cord-353633-a4pu6rlu	531	11	acids	acid	NNS
cord-353633-a4pu6rlu	531	12	in	in	IN
cord-353633-a4pu6rlu	531	13	non	non	JJ
cord-353633-a4pu6rlu	531	14	-	-	JJ
cord-353633-a4pu6rlu	531	15	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	531	16	fatty	fatty	JJ
cord-353633-a4pu6rlu	531	17	liver	liver	NN
cord-353633-a4pu6rlu	531	18	disease	disease	NN
cord-353633-a4pu6rlu	532	1	5-lipoxygenase	5-lipoxygenase	CD
cord-353633-a4pu6rlu	532	2	activating	activate	VBG
cord-353633-a4pu6rlu	532	3	protein	protein	NN
cord-353633-a4pu6rlu	532	4	signals	signal	NNS
cord-353633-a4pu6rlu	532	5	adipose	adipose	JJ
cord-353633-a4pu6rlu	532	6	tissue	tissue	NN
cord-353633-a4pu6rlu	532	7	inflammation	inflammation	NN
cord-353633-a4pu6rlu	532	8	and	and	CC
cord-353633-a4pu6rlu	532	9	lipid	lipid	NN
cord-353633-a4pu6rlu	532	10	dysfunction	dysfunction	NN
cord-353633-a4pu6rlu	532	11	in	in	IN
cord-353633-a4pu6rlu	532	12	experimental	experimental	JJ
cord-353633-a4pu6rlu	532	13	obesity	obesity	NN
cord-353633-a4pu6rlu	533	1	The	the	DT
cord-353633-a4pu6rlu	533	2	specialized	specialized	JJ
cord-353633-a4pu6rlu	533	3	proresolving	proresolve	VBG
cord-353633-a4pu6rlu	533	4	lipid	lipid	NN
cord-353633-a4pu6rlu	533	5	mediator	mediator	NN
cord-353633-a4pu6rlu	533	6	maresin	maresin	NNP
cord-353633-a4pu6rlu	533	7	1	1	CD
cord-353633-a4pu6rlu	533	8	protects	protect	VBZ
cord-353633-a4pu6rlu	533	9	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	533	10	from	from	IN
cord-353633-a4pu6rlu	533	11	lipotoxic	lipotoxic	NNP
cord-353633-a4pu6rlu	533	12	and	and	CC
cord-353633-a4pu6rlu	533	13	hypoxia	hypoxia	NN
cord-353633-a4pu6rlu	533	14	-	-	HYPH
cord-353633-a4pu6rlu	533	15	induced	induce	VBN
cord-353633-a4pu6rlu	533	16	endoplasmic	endoplasmic	NN
cord-353633-a4pu6rlu	533	17	reticulum	reticulum	NN
cord-353633-a4pu6rlu	533	18	stress	stress	NN
cord-353633-a4pu6rlu	533	19	Metabolomic	Metabolomic	NNP
cord-353633-a4pu6rlu	533	20	-	-	HYPH
cord-353633-a4pu6rlu	533	21	based	base	VBN
cord-353633-a4pu6rlu	533	22	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	533	23	serum	serum	NN
cord-353633-a4pu6rlu	533	24	test	test	NN
cord-353633-a4pu6rlu	533	25	to	to	TO
cord-353633-a4pu6rlu	533	26	diagnose	diagnose	VB
cord-353633-a4pu6rlu	533	27	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	533	28	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	533	29	:	:	:
cord-353633-a4pu6rlu	533	30	Results	result	NNS
cord-353633-a4pu6rlu	533	31	from	from	IN
cord-353633-a4pu6rlu	533	32	discovery	discovery	NN
cord-353633-a4pu6rlu	533	33	and	and	CC
cord-353633-a4pu6rlu	533	34	validation	validation	NN
cord-353633-a4pu6rlu	533	35	cohorts	cohort	NNS
cord-353633-a4pu6rlu	533	36	Use	Use	NNP
cord-353633-a4pu6rlu	533	37	of	of	IN
cord-353633-a4pu6rlu	533	38	a	a	DT
cord-353633-a4pu6rlu	533	39	metabolomic	metabolomic	JJ
cord-353633-a4pu6rlu	533	40	approach	approach	NN
cord-353633-a4pu6rlu	533	41	to	to	IN
cord-353633-a4pu6rlu	533	42	non	non	JJ
cord-353633-a4pu6rlu	533	43	-	-	JJ
cord-353633-a4pu6rlu	533	44	invasively	invasively	RB
cord-353633-a4pu6rlu	533	45	diagnose	diagnose	VB
cord-353633-a4pu6rlu	533	46	non	non	JJ
cord-353633-a4pu6rlu	533	47	-	-	JJ
cord-353633-a4pu6rlu	533	48	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	533	49	fatty	fatty	JJ
cord-353633-a4pu6rlu	533	50	liver	liver	NN
cord-353633-a4pu6rlu	533	51	disease	disease	NN
cord-353633-a4pu6rlu	533	52	in	in	IN
cord-353633-a4pu6rlu	533	53	patients	patient	NNS
cord-353633-a4pu6rlu	533	54	with	with	IN
cord-353633-a4pu6rlu	533	55	type	type	NN
cord-353633-a4pu6rlu	533	56	2	2	CD
cord-353633-a4pu6rlu	533	57	diabetes	diabetes	NN
cord-353633-a4pu6rlu	533	58	mellitus	mellitus	NN
cord-353633-a4pu6rlu	533	59	Fatty	fatty	JJ
cord-353633-a4pu6rlu	533	60	liver	liver	NN
cord-353633-a4pu6rlu	533	61	in	in	IN
cord-353633-a4pu6rlu	533	62	lipodystrophy	lipodystrophy	NN
cord-353633-a4pu6rlu	533	63	:	:	:
cord-353633-a4pu6rlu	534	1	A	a	DT
cord-353633-a4pu6rlu	534	2	review	review	NN
cord-353633-a4pu6rlu	534	3	with	with	IN
cord-353633-a4pu6rlu	534	4	a	a	DT
cord-353633-a4pu6rlu	534	5	focus	focus	NN
cord-353633-a4pu6rlu	534	6	on	on	IN
cord-353633-a4pu6rlu	534	7	therapeutic	therapeutic	JJ
cord-353633-a4pu6rlu	534	8	perspectives	perspective	NNS
cord-353633-a4pu6rlu	534	9	of	of	IN
cord-353633-a4pu6rlu	534	10	adiponectin	adiponectin	NN
cord-353633-a4pu6rlu	534	11	and/or	and/or	CC
cord-353633-a4pu6rlu	534	12	leptin	leptin	NN
cord-353633-a4pu6rlu	534	13	replacement	replacement	NN
cord-353633-a4pu6rlu	534	14	Serum	serum	NN
cord-353633-a4pu6rlu	534	15	metabolites	metabolite	NNS
cord-353633-a4pu6rlu	534	16	detect	detect	VBP
cord-353633-a4pu6rlu	534	17	the	the	DT
cord-353633-a4pu6rlu	534	18	presence	presence	NN
cord-353633-a4pu6rlu	534	19	of	of	IN
cord-353633-a4pu6rlu	534	20	advanced	advanced	JJ
cord-353633-a4pu6rlu	534	21	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	534	22	in	in	IN
cord-353633-a4pu6rlu	534	23	derivation	derivation	NN
cord-353633-a4pu6rlu	534	24	and	and	CC
cord-353633-a4pu6rlu	534	25	validation	validation	NN
cord-353633-a4pu6rlu	534	26	cohorts	cohort	NNS
cord-353633-a4pu6rlu	534	27	of	of	IN
cord-353633-a4pu6rlu	534	28	patients	patient	NNS
cord-353633-a4pu6rlu	534	29	with	with	IN
cord-353633-a4pu6rlu	534	30	non	non	JJ
cord-353633-a4pu6rlu	534	31	-	-	JJ
cord-353633-a4pu6rlu	534	32	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	534	33	fatty	fatty	JJ
cord-353633-a4pu6rlu	534	34	liver	liver	NN
cord-353633-a4pu6rlu	534	35	disease	disease	NN
cord-353633-a4pu6rlu	534	36	Development	Development	NNP
cord-353633-a4pu6rlu	534	37	of	of	IN
cord-353633-a4pu6rlu	534	38	a	a	DT
cord-353633-a4pu6rlu	534	39	Plasma	Plasma	NNP
cord-353633-a4pu6rlu	534	40	Screening	Screening	NNP
cord-353633-a4pu6rlu	534	41	Panel	Panel	NNP
cord-353633-a4pu6rlu	534	42	for	for	IN
cord-353633-a4pu6rlu	534	43	Pediatric	Pediatric	NNP
cord-353633-a4pu6rlu	534	44	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	534	45	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	534	46	Liver	Liver	NNP
cord-353633-a4pu6rlu	534	47	Disease	Disease	NNP
cord-353633-a4pu6rlu	534	48	Using	use	VBG
cord-353633-a4pu6rlu	534	49	Metabolomics	Metabolomics	NNPS
cord-353633-a4pu6rlu	534	50	Farnesoid	Farnesoid	NNP
cord-353633-a4pu6rlu	534	51	X	X	NNP
cord-353633-a4pu6rlu	534	52	nuclear	nuclear	JJ
cord-353633-a4pu6rlu	534	53	receptor	receptor	NN
cord-353633-a4pu6rlu	534	54	ligand	ligand	NN
cord-353633-a4pu6rlu	534	55	obeticholic	obeticholic	JJ
cord-353633-a4pu6rlu	534	56	acid	acid	NN
cord-353633-a4pu6rlu	534	57	for	for	IN
cord-353633-a4pu6rlu	534	58	noncirrhotic	noncirrhotic	JJ
cord-353633-a4pu6rlu	534	59	,	,	,
cord-353633-a4pu6rlu	534	60	non	non	JJ
cord-353633-a4pu6rlu	534	61	-	-	JJ
cord-353633-a4pu6rlu	534	62	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	534	63	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	534	64	(	(	-LRB-
cord-353633-a4pu6rlu	534	65	FLINT	FLINT	NNP
cord-353633-a4pu6rlu	534	66	)	)	-RRB-
cord-353633-a4pu6rlu	534	67	:	:	:
cord-353633-a4pu6rlu	534	68	a	a	DT
cord-353633-a4pu6rlu	534	69	multicentre	multicentre	NNP
cord-353633-a4pu6rlu	534	70	,	,	,
cord-353633-a4pu6rlu	534	71	randomised	randomised	JJ
cord-353633-a4pu6rlu	534	72	,	,	,
cord-353633-a4pu6rlu	534	73	placebocontrolled	placebocontrolled	JJ
cord-353633-a4pu6rlu	534	74	trial	trial	NN
cord-353633-a4pu6rlu	534	75	Obeticholic	Obeticholic	NNP
cord-353633-a4pu6rlu	534	76	acid	acid	NN
cord-353633-a4pu6rlu	534	77	for	for	IN
cord-353633-a4pu6rlu	534	78	the	the	DT
cord-353633-a4pu6rlu	534	79	treatment	treatment	NN
cord-353633-a4pu6rlu	534	80	of	of	IN
cord-353633-a4pu6rlu	534	81	non	non	JJ
cord-353633-a4pu6rlu	534	82	-	-	JJ
cord-353633-a4pu6rlu	534	83	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	534	84	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	534	85	:	:	:
cord-353633-a4pu6rlu	534	86	interim	interim	JJ
cord-353633-a4pu6rlu	534	87	analysis	analysis	NN
cord-353633-a4pu6rlu	534	88	from	from	IN
cord-353633-a4pu6rlu	534	89	a	a	DT
cord-353633-a4pu6rlu	534	90	multicentre	multicentre	NNP
cord-353633-a4pu6rlu	534	91	,	,	,
cord-353633-a4pu6rlu	534	92	randomised	randomised	JJ
cord-353633-a4pu6rlu	534	93	,	,	,
cord-353633-a4pu6rlu	534	94	placebo	placebo	NN
cord-353633-a4pu6rlu	534	95	-	-	HYPH
cord-353633-a4pu6rlu	534	96	controlled	control	VBN
cord-353633-a4pu6rlu	534	97	phase	phase	NN
cord-353633-a4pu6rlu	534	98	3	3	CD
cord-353633-a4pu6rlu	534	99	trial	trial	NN
cord-353633-a4pu6rlu	534	100	Obeticholic	Obeticholic	NNP
cord-353633-a4pu6rlu	534	101	acid	acid	NN
cord-353633-a4pu6rlu	534	102	for	for	IN
cord-353633-a4pu6rlu	534	103	the	the	DT
cord-353633-a4pu6rlu	534	104	treatment	treatment	NN
cord-353633-a4pu6rlu	534	105	of	of	IN
cord-353633-a4pu6rlu	534	106	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	534	107	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	534	108	:	:	:
cord-353633-a4pu6rlu	534	109	Expectations	expectation	NNS
cord-353633-a4pu6rlu	534	110	and	and	CC
cord-353633-a4pu6rlu	534	111	concerns	concern	NNS
cord-353633-a4pu6rlu	534	112	Hepatoprotective	Hepatoprotective	NNP
cord-353633-a4pu6rlu	534	113	effects	effect	NNS
cord-353633-a4pu6rlu	534	114	of	of	IN
cord-353633-a4pu6rlu	534	115	the	the	DT
cord-353633-a4pu6rlu	534	116	dual	dual	JJ
cord-353633-a4pu6rlu	534	117	peroxisome	peroxisome	NN
cord-353633-a4pu6rlu	534	118	proliferator	proliferator	NN
cord-353633-a4pu6rlu	534	119	-	-	HYPH
cord-353633-a4pu6rlu	534	120	activated	activate	VBN
cord-353633-a4pu6rlu	534	121	receptor	receptor	NN
cord-353633-a4pu6rlu	534	122	alpha	alpha	NN
cord-353633-a4pu6rlu	534	123	/	/	SYM
cord-353633-a4pu6rlu	534	124	delta	delta	NN
cord-353633-a4pu6rlu	534	125	agonist	agonist	NN
cord-353633-a4pu6rlu	534	126	,	,	,
cord-353633-a4pu6rlu	534	127	GFT505	GFT505	NNP
cord-353633-a4pu6rlu	534	128	,	,	,
cord-353633-a4pu6rlu	534	129	in	in	IN
cord-353633-a4pu6rlu	534	130	rodent	rodent	NN
cord-353633-a4pu6rlu	534	131	models	model	NNS
cord-353633-a4pu6rlu	534	132	of	of	IN
cord-353633-a4pu6rlu	534	133	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	534	134	fatty	fatty	JJ
cord-353633-a4pu6rlu	534	135	liver	liver	NN
cord-353633-a4pu6rlu	534	136	disease	disease	NN
cord-353633-a4pu6rlu	534	137	/	/	SYM
cord-353633-a4pu6rlu	534	138	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	534	139	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	535	1	The	the	DT
cord-353633-a4pu6rlu	535	2	selective	selective	JJ
cord-353633-a4pu6rlu	535	3	peroxisome	peroxisome	NN
cord-353633-a4pu6rlu	535	4	proliferator	proliferator	NN
cord-353633-a4pu6rlu	535	5	-	-	HYPH
cord-353633-a4pu6rlu	535	6	activated	activate	VBN
cord-353633-a4pu6rlu	535	7	receptor	receptor	NN
cord-353633-a4pu6rlu	535	8	-	-	HYPH
cord-353633-a4pu6rlu	535	9	delta	delta	NN
cord-353633-a4pu6rlu	535	10	agonist	agonist	NN
cord-353633-a4pu6rlu	535	11	seladelpar	seladelpar	NNP
cord-353633-a4pu6rlu	535	12	reverses	reverse	VBZ
cord-353633-a4pu6rlu	535	13	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	535	14	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	535	15	pathology	pathology	NN
cord-353633-a4pu6rlu	535	16	by	by	IN
cord-353633-a4pu6rlu	535	17	abrogating	abrogate	VBG
cord-353633-a4pu6rlu	535	18	lipotoxicity	lipotoxicity	NN
cord-353633-a4pu6rlu	535	19	in	in	IN
cord-353633-a4pu6rlu	535	20	diabetic	diabetic	JJ
cord-353633-a4pu6rlu	535	21	obese	obese	JJ
cord-353633-a4pu6rlu	535	22	mice	mouse	NNS
cord-353633-a4pu6rlu	535	23	GENFIT	GENFIT	NNP
cord-353633-a4pu6rlu	535	24	-	-	HYPH
cord-353633-a4pu6rlu	535	25	Announces	announce	NNS
cord-353633-a4pu6rlu	535	26	-	-	HYPH
cord-353633-a4pu6rlu	535	27	Results	Results	NNP
cord-353633-a4pu6rlu	535	28	-	-	HYPH
cord-353633-a4pu6rlu	535	29	from	from	IN
cord-353633-a4pu6rlu	535	30	-	-	HYPH
cord-353633-a4pu6rlu	535	31	Interim	Interim	NNP
cord-353633-a4pu6rlu	535	32	-	-	HYPH
cord-353633-a4pu6rlu	535	33	Analysis	Analysis	NNP
cord-353633-a4pu6rlu	535	34	-	-	HYPH
cord-353633-a4pu6rlu	535	35	of	of	IN
cord-353633-a4pu6rlu	535	36	-	-	HYPH
cord-353633-a4pu6rlu	535	37	RESOLVE	resolve	NN
cord-353633-a4pu6rlu	535	38	-	-	HYPH
cord-353633-a4pu6rlu	535	39	IT	it	NN
cord-353633-a4pu6rlu	535	40	-	-	HYPH
cord-353633-a4pu6rlu	535	41	Phase-3-Trial	Phase-3-Trial	NNP
cord-353633-a4pu6rlu	535	42	-	-	HYPH
cord-353633-a4pu6rlu	535	43	of	of	IN
cord-353633-a4pu6rlu	535	44	-	-	HYPH
cord-353633-a4pu6rlu	535	45	Elafibranor	elafibranor	NN
cord-353633-a4pu6rlu	535	46	-	-	HYPH
cord-353633-a4pu6rlu	535	47	in	in	IN
cord-353633-a4pu6rlu	535	48	-	-	HYPH
cord-353633-a4pu6rlu	535	49	Adults	Adults	NNP
cord-353633-a4pu6rlu	535	50	-	-	HYPH
cord-353633-a4pu6rlu	535	51	with	with	IN
cord-353633-a4pu6rlu	535	52	-	-	HYPH
cord-353633-a4pu6rlu	535	53	NASH	NASH	NNP
cord-353633-a4pu6rlu	535	54	-	-	HYPH
cord-353633-a4pu6rlu	535	55	and	and	CC
cord-353633-a4pu6rlu	535	56	-	-	HYPH
cord-353633-a4pu6rlu	535	57	Fibrosis.html	fibrosis.html	ADD
cord-353633-a4pu6rlu	536	1	Agonist	agonist	NN
cord-353633-a4pu6rlu	536	2	of	of	IN
cord-353633-a4pu6rlu	536	3	the	the	DT
cord-353633-a4pu6rlu	536	4	Peroxisome	Peroxisome	NNP
cord-353633-a4pu6rlu	536	5	Proliferator	Proliferator	NNP
cord-353633-a4pu6rlu	536	6	-	-	HYPH
cord-353633-a4pu6rlu	536	7	Activated	Activated	NNP
cord-353633-a4pu6rlu	536	8	Receptor	receptor	NN
cord-353633-a4pu6rlu	536	9	-	-	HYPH
cord-353633-a4pu6rlu	536	10	alpha	alpha	NN
cord-353633-a4pu6rlu	536	11	anddelta	anddelta	NNS
cord-353633-a4pu6rlu	536	12	,	,	,
cord-353633-a4pu6rlu	536	13	Induces	Induces	NNP
cord-353633-a4pu6rlu	536	14	Resolution	Resolution	NNP
cord-353633-a4pu6rlu	536	15	of	of	IN
cord-353633-a4pu6rlu	536	16	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	536	17	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	536	18	Without	without	IN
cord-353633-a4pu6rlu	536	19	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	536	20	Worsening	worsen	VBG
cord-353633-a4pu6rlu	536	21	Selective	selective	JJ
cord-353633-a4pu6rlu	536	22	Tissue	tissue	NN
cord-353633-a4pu6rlu	536	23	Distribution	distribution	NN
cord-353633-a4pu6rlu	536	24	Mediates	mediate	VBZ
cord-353633-a4pu6rlu	537	1	Tissue	tissue	NN
cord-353633-a4pu6rlu	537	2	-	-	HYPH
cord-353633-a4pu6rlu	537	3	Dependent	dependent	JJ
cord-353633-a4pu6rlu	537	4	PPARgamma	PPARgamma	NNP
cord-353633-a4pu6rlu	537	5	Activation	Activation	NNP
cord-353633-a4pu6rlu	537	6	and	and	CC
cord-353633-a4pu6rlu	537	7	Insulin	Insulin	NNP
cord-353633-a4pu6rlu	537	8	Sensitization	Sensitization	NNP
cord-353633-a4pu6rlu	537	9	by	by	IN
cord-353633-a4pu6rlu	537	10	INT131	INT131	NNP
cord-353633-a4pu6rlu	538	1	,	,	,
cord-353633-a4pu6rlu	538	2	a	a	DT
cord-353633-a4pu6rlu	538	3	Selective	selective	JJ
cord-353633-a4pu6rlu	538	4	PPARgamma	ppargamma	NN
cord-353633-a4pu6rlu	538	5	Modulator	Modulator	NNP
cord-353633-a4pu6rlu	538	6	Dual	Dual	NNP
cord-353633-a4pu6rlu	538	7	PPARalpha	pparalpha	NN
cord-353633-a4pu6rlu	538	8	/	/	SYM
cord-353633-a4pu6rlu	538	9	gamma	gamma	NN
cord-353633-a4pu6rlu	538	10	agonist	agonist	NN
cord-353633-a4pu6rlu	538	11	saroglitazar	saroglitazar	NN
cord-353633-a4pu6rlu	538	12	improves	improve	VBZ
cord-353633-a4pu6rlu	538	13	liver	liver	NN
cord-353633-a4pu6rlu	538	14	histopathology	histopathology	NN
cord-353633-a4pu6rlu	538	15	and	and	CC
cord-353633-a4pu6rlu	538	16	biochemistry	biochemistry	NN
cord-353633-a4pu6rlu	538	17	in	in	IN
cord-353633-a4pu6rlu	538	18	experimental	experimental	JJ
cord-353633-a4pu6rlu	538	19	NASH	NASH	NNP
cord-353633-a4pu6rlu	538	20	models	model	NNS
cord-353633-a4pu6rlu	539	1	Effect	effect	NN
cord-353633-a4pu6rlu	539	2	of	of	IN
cord-353633-a4pu6rlu	539	3	saroglitazar	saroglitazar	NN
cord-353633-a4pu6rlu	539	4	2	2	CD
cord-353633-a4pu6rlu	539	5	mg	mg	NNP
cord-353633-a4pu6rlu	539	6	and	and	CC
cord-353633-a4pu6rlu	539	7	4	4	CD
cord-353633-a4pu6rlu	539	8	mg	mg	NN
cord-353633-a4pu6rlu	539	9	on	on	IN
cord-353633-a4pu6rlu	539	10	glycemic	glycemic	NN
cord-353633-a4pu6rlu	539	11	control	control	NN
cord-353633-a4pu6rlu	539	12	,	,	,
cord-353633-a4pu6rlu	539	13	lipid	lipid	NN
cord-353633-a4pu6rlu	539	14	profile	profile	NN
cord-353633-a4pu6rlu	539	15	and	and	CC
cord-353633-a4pu6rlu	539	16	cardiovascular	cardiovascular	JJ
cord-353633-a4pu6rlu	539	17	disease	disease	NN
cord-353633-a4pu6rlu	539	18	risk	risk	NN
cord-353633-a4pu6rlu	539	19	in	in	IN
cord-353633-a4pu6rlu	539	20	patients	patient	NNS
cord-353633-a4pu6rlu	539	21	with	with	IN
cord-353633-a4pu6rlu	539	22	type	type	NN
cord-353633-a4pu6rlu	539	23	2	2	CD
cord-353633-a4pu6rlu	539	24	diabetes	diabetes	NN
cord-353633-a4pu6rlu	539	25	mellitus	mellitus	NN
cord-353633-a4pu6rlu	539	26	:	:	:
cord-353633-a4pu6rlu	539	27	a	a	DT
cord-353633-a4pu6rlu	539	28	56-week	56-week	CD
cord-353633-a4pu6rlu	539	29	,	,	,
cord-353633-a4pu6rlu	539	30	randomized	randomized	JJ
cord-353633-a4pu6rlu	539	31	,	,	,
cord-353633-a4pu6rlu	539	32	double	double	JJ
cord-353633-a4pu6rlu	539	33	blind	blind	JJ
cord-353633-a4pu6rlu	539	34	,	,	,
cord-353633-a4pu6rlu	539	35	phase	phase	VBP
cord-353633-a4pu6rlu	539	36	3	3	CD
cord-353633-a4pu6rlu	539	37	study	study	NN
cord-353633-a4pu6rlu	539	38	(	(	-LRB-
cord-353633-a4pu6rlu	539	39	PRESS	press	NN
cord-353633-a4pu6rlu	539	40	XII	XII	NNP
cord-353633-a4pu6rlu	539	41	study	study	NN
cord-353633-a4pu6rlu	539	42	)	)	-RRB-
cord-353633-a4pu6rlu	540	1	lanifibranor	lanifibranor	NNP
cord-353633-a4pu6rlu	540	2	-	-	HYPH
cord-353633-a4pu6rlu	540	3	meets	meet	VBZ
cord-353633-a4pu6rlu	540	4	-	-	HYPH
cord-353633-a4pu6rlu	540	5	the	the	DT
cord-353633-a4pu6rlu	540	6	-	-	HYPH
cord-353633-a4pu6rlu	540	7	primary	primary	JJ
cord-353633-a4pu6rlu	540	8	-	-	HYPH
cord-353633-a4pu6rlu	540	9	andkey	andkey	NN
cord-353633-a4pu6rlu	540	10	-	-	HYPH
cord-353633-a4pu6rlu	540	11	secondary	secondary	JJ
cord-353633-a4pu6rlu	540	12	-	-	HYPH
cord-353633-a4pu6rlu	540	13	endpoints	endpoint	NNS
cord-353633-a4pu6rlu	540	14	-	-	HYPH
cord-353633-a4pu6rlu	540	15	in	in	IN
cord-353633-a4pu6rlu	540	16	-	-	HYPH
cord-353633-a4pu6rlu	540	17	the	the	DT
cord-353633-a4pu6rlu	540	18	-	-	HYPH
cord-353633-a4pu6rlu	540	19	Phase	phase	NN
cord-353633-a4pu6rlu	540	20	-	-	HYPH
cord-353633-a4pu6rlu	540	21	IIb	iib	JJ
cord-353633-a4pu6rlu	540	22	-	-	HYPH
cord-353633-a4pu6rlu	540	23	NATIVE	native	JJ
cord-353633-a4pu6rlu	540	24	-	-	HYPH
cord-353633-a4pu6rlu	540	25	clinical	clinical	JJ
cord-353633-a4pu6rlu	540	26	-	-	HYPH
cord-353633-a4pu6rlu	540	27	trial	trial	NN
cord-353633-a4pu6rlu	540	28	-	-	HYPH
cord-353633-a4pu6rlu	540	29	in	in	IN
cord-353633-a4pu6rlu	540	30	-	-	HYPH
cord-353633-a4pu6rlu	540	31	non	non	NN
cord-353633-a4pu6rlu	540	32	-	-	JJ
cord-353633-a4pu6rlu	540	33	alcoholicsteatohepatitis-	alcoholicsteatohepatitis-	JJ
cord-353633-a4pu6rlu	541	1	NASH.html	NASH.html	NNP
cord-353633-a4pu6rlu	541	2	Acetyl	Acetyl	NNP
cord-353633-a4pu6rlu	541	3	-	-	HYPH
cord-353633-a4pu6rlu	541	4	CoA	coa	NN
cord-353633-a4pu6rlu	541	5	Carboxylase	Carboxylase	NNP
cord-353633-a4pu6rlu	541	6	Inhibitor	Inhibitor	NNP
cord-353633-a4pu6rlu	541	7	GS-0976	GS-0976	NNP
cord-353633-a4pu6rlu	541	8	for	for	IN
cord-353633-a4pu6rlu	541	9	12	12	CD
cord-353633-a4pu6rlu	541	10	Weeks	week	NNS
cord-353633-a4pu6rlu	542	1	Reduces	reduce	VBZ
cord-353633-a4pu6rlu	542	2	Hepatic	Hepatic	NNP
cord-353633-a4pu6rlu	542	3	De	De	NNP
cord-353633-a4pu6rlu	542	4	Novo	Novo	NNP
cord-353633-a4pu6rlu	542	5	Lipogenesis	Lipogenesis	NNP
cord-353633-a4pu6rlu	542	6	and	and	CC
cord-353633-a4pu6rlu	542	7	Steatosis	Steatosis	NNP
cord-353633-a4pu6rlu	542	8	in	in	IN
cord-353633-a4pu6rlu	542	9	Patients	Patients	NNP
cord-353633-a4pu6rlu	542	10	With	with	IN
cord-353633-a4pu6rlu	542	11	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	542	12	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	542	13	ASB14780	ASB14780	NNP
cord-353633-a4pu6rlu	542	14	,	,	,
cord-353633-a4pu6rlu	542	15	an	an	DT
cord-353633-a4pu6rlu	542	16	Orally	Orally	NNP
cord-353633-a4pu6rlu	542	17	Active	Active	NNP
cord-353633-a4pu6rlu	542	18	Inhibitor	Inhibitor	NNP
cord-353633-a4pu6rlu	542	19	of	of	IN
cord-353633-a4pu6rlu	542	20	Group	Group	NNP
cord-353633-a4pu6rlu	542	21	IVA	IVA	NNP
cord-353633-a4pu6rlu	542	22	Phospholipase	Phospholipase	NNP
cord-353633-a4pu6rlu	542	23	A2	A2	NNP
cord-353633-a4pu6rlu	542	24	,	,	,
cord-353633-a4pu6rlu	542	25	Is	be	VBZ
cord-353633-a4pu6rlu	542	26	a	a	DT
cord-353633-a4pu6rlu	542	27	Pharmacotherapeutic	Pharmacotherapeutic	NNP
cord-353633-a4pu6rlu	542	28	Candidate	Candidate	NNP
cord-353633-a4pu6rlu	542	29	for	for	IN
cord-353633-a4pu6rlu	542	30	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	542	31	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	542	32	Liver	Liver	NNP
cord-353633-a4pu6rlu	542	33	Disease	Disease	NNP
cord-353633-a4pu6rlu	542	34	Elevation	Elevation	NNP
cord-353633-a4pu6rlu	542	35	of	of	IN
cord-353633-a4pu6rlu	542	36	20-carbon	20-carbon	CD
cord-353633-a4pu6rlu	542	37	long	long	JJ
cord-353633-a4pu6rlu	542	38	chain	chain	NN
cord-353633-a4pu6rlu	542	39	bases	basis	NNS
cord-353633-a4pu6rlu	542	40	due	due	JJ
cord-353633-a4pu6rlu	542	41	to	to	IN
cord-353633-a4pu6rlu	542	42	a	a	DT
cord-353633-a4pu6rlu	542	43	mutation	mutation	NN
cord-353633-a4pu6rlu	542	44	in	in	IN
cord-353633-a4pu6rlu	542	45	serine	serine	NN
cord-353633-a4pu6rlu	542	46	palmitoyltransferase	palmitoyltransferase	NN
cord-353633-a4pu6rlu	542	47	small	small	JJ
cord-353633-a4pu6rlu	542	48	subunit	subunit	NN
cord-353633-a4pu6rlu	542	49	b	b	NN
cord-353633-a4pu6rlu	542	50	results	result	NNS
cord-353633-a4pu6rlu	542	51	in	in	IN
cord-353633-a4pu6rlu	542	52	neurodegeneration	neurodegeneration	NN
cord-353633-a4pu6rlu	542	53	Intestine	intestine	NN
cord-353633-a4pu6rlu	542	54	-	-	HYPH
cord-353633-a4pu6rlu	542	55	selective	selective	JJ
cord-353633-a4pu6rlu	542	56	farnesoid	farnesoid	JJ
cord-353633-a4pu6rlu	542	57	X	x	NN
cord-353633-a4pu6rlu	542	58	receptor	receptor	NN
cord-353633-a4pu6rlu	542	59	inhibition	inhibition	NN
cord-353633-a4pu6rlu	542	60	improves	improve	VBZ
cord-353633-a4pu6rlu	542	61	obesity	obesity	NN
cord-353633-a4pu6rlu	542	62	-	-	HYPH
cord-353633-a4pu6rlu	542	63	related	relate	VBN
cord-353633-a4pu6rlu	542	64	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	542	65	dysfunction	dysfunction	NN
cord-353633-a4pu6rlu	542	66	Omega-3	omega-3	NN
cord-353633-a4pu6rlu	542	67	supplementation	supplementation	NN
cord-353633-a4pu6rlu	542	68	and	and	CC
cord-353633-a4pu6rlu	542	69	non	non	JJ
cord-353633-a4pu6rlu	542	70	-	-	JJ
cord-353633-a4pu6rlu	542	71	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	542	72	fatty	fatty	JJ
cord-353633-a4pu6rlu	542	73	liver	liver	NN
cord-353633-a4pu6rlu	542	74	disease	disease	NN
cord-353633-a4pu6rlu	542	75	:	:	:
cord-353633-a4pu6rlu	542	76	a	a	DT
cord-353633-a4pu6rlu	542	77	systematic	systematic	JJ
cord-353633-a4pu6rlu	542	78	review	review	NN
cord-353633-a4pu6rlu	542	79	and	and	CC
cord-353633-a4pu6rlu	542	80	meta	meta	NNP
cord-353633-a4pu6rlu	542	81	-	-	HYPH
cord-353633-a4pu6rlu	542	82	analysis	analysis	NN
cord-353633-a4pu6rlu	542	83	No	no	DT
cord-353633-a4pu6rlu	542	84	significant	significant	JJ
cord-353633-a4pu6rlu	542	85	effects	effect	NNS
cord-353633-a4pu6rlu	542	86	of	of	IN
cord-353633-a4pu6rlu	542	87	ethyl	ethyl	NN
cord-353633-a4pu6rlu	542	88	-	-	HYPH
cord-353633-a4pu6rlu	542	89	eicosapentanoic	eicosapentanoic	NN
cord-353633-a4pu6rlu	542	90	acid	acid	NN
cord-353633-a4pu6rlu	542	91	on	on	IN
cord-353633-a4pu6rlu	542	92	histologic	histologic	JJ
cord-353633-a4pu6rlu	542	93	features	feature	NNS
cord-353633-a4pu6rlu	542	94	of	of	IN
cord-353633-a4pu6rlu	542	95	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	542	96	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	542	97	in	in	IN
cord-353633-a4pu6rlu	542	98	a	a	DT
cord-353633-a4pu6rlu	542	99	phase	phase	NN
cord-353633-a4pu6rlu	542	100	2	2	CD
cord-353633-a4pu6rlu	542	101	trial	trial	NN
cord-353633-a4pu6rlu	542	102	Effects	effect	NNS
cord-353633-a4pu6rlu	542	103	of	of	IN
cord-353633-a4pu6rlu	542	104	purified	purify	VBN
cord-353633-a4pu6rlu	542	105	eicosapentaenoic	eicosapentaenoic	NN
cord-353633-a4pu6rlu	542	106	and	and	CC
cord-353633-a4pu6rlu	542	107	docosahexaenoic	docosahexaenoic	NN
cord-353633-a4pu6rlu	542	108	acids	acid	NNS
cord-353633-a4pu6rlu	542	109	in	in	IN
cord-353633-a4pu6rlu	542	110	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	542	111	fatty	fatty	JJ
cord-353633-a4pu6rlu	542	112	liver	liver	NN
cord-353633-a4pu6rlu	542	113	disease	disease	NN
cord-353633-a4pu6rlu	542	114	:	:	:
cord-353633-a4pu6rlu	542	115	results	result	NNS
cord-353633-a4pu6rlu	542	116	from	from	IN
cord-353633-a4pu6rlu	542	117	the	the	DT
cord-353633-a4pu6rlu	542	118	Welcome	welcome	NN
cord-353633-a4pu6rlu	542	119	*	*	NFP
cord-353633-a4pu6rlu	542	120	study	study	NN
cord-353633-a4pu6rlu	542	121	Molecular	molecular	JJ
cord-353633-a4pu6rlu	542	122	interplay	interplay	NN
cord-353633-a4pu6rlu	542	123	between	between	IN
cord-353633-a4pu6rlu	542	124	Delta5	Delta5	NNP
cord-353633-a4pu6rlu	542	125	/	/	SYM
cord-353633-a4pu6rlu	542	126	Delta6	Delta6	NNP
cord-353633-a4pu6rlu	542	127	desaturases	desaturases	NNPS
cord-353633-a4pu6rlu	542	128	and	and	CC
cord-353633-a4pu6rlu	542	129	longchain	longchain	VBP
cord-353633-a4pu6rlu	542	130	fatty	fatty	JJ
cord-353633-a4pu6rlu	542	131	acids	acid	NNS
cord-353633-a4pu6rlu	542	132	in	in	IN
cord-353633-a4pu6rlu	542	133	the	the	DT
cord-353633-a4pu6rlu	542	134	pathogenesis	pathogenesis	NN
cord-353633-a4pu6rlu	542	135	of	of	IN
cord-353633-a4pu6rlu	542	136	non	non	JJ
cord-353633-a4pu6rlu	542	137	-	-	JJ
cord-353633-a4pu6rlu	542	138	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	542	139	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	542	140	Group	Group	NNP
cord-353633-a4pu6rlu	542	141	IVA	IVA	NNP
cord-353633-a4pu6rlu	542	142	phospholipase	phospholipase	NN
cord-353633-a4pu6rlu	542	143	A(2	A(2	NNP
cord-353633-a4pu6rlu	542	144	)	)	-RRB-
cord-353633-a4pu6rlu	542	145	deficiency	deficiency	NN
cord-353633-a4pu6rlu	542	146	prevents	prevent	VBZ
cord-353633-a4pu6rlu	542	147	CCl4-induced	CCl4-induced	NNP
cord-353633-a4pu6rlu	542	148	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	542	149	cell	cell	NN
cord-353633-a4pu6rlu	542	150	death	death	NN
cord-353633-a4pu6rlu	542	151	through	through	IN
cord-353633-a4pu6rlu	542	152	the	the	DT
cord-353633-a4pu6rlu	542	153	enhancement	enhancement	NN
cord-353633-a4pu6rlu	542	154	of	of	IN
cord-353633-a4pu6rlu	542	155	autophagy	autophagy	NN
cord-353633-a4pu6rlu	542	156	5-lipoxygenase	5-lipoxygenase	CD
cord-353633-a4pu6rlu	542	157	deficiency	deficiency	NN
cord-353633-a4pu6rlu	543	1	reduces	reduce	VBZ
cord-353633-a4pu6rlu	543	2	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	543	3	inflammation	inflammation	NN
cord-353633-a4pu6rlu	543	4	and	and	CC
cord-353633-a4pu6rlu	543	5	tumor	tumor	NN
cord-353633-a4pu6rlu	543	6	necrosis	necrosis	NN
cord-353633-a4pu6rlu	543	7	factor	factor	NN
cord-353633-a4pu6rlu	543	8	alpha	alpha	NN
cord-353633-a4pu6rlu	543	9	-	-	HYPH
cord-353633-a4pu6rlu	543	10	induced	induce	VBN
cord-353633-a4pu6rlu	543	11	hepatocyte	hepatocyte	NN
cord-353633-a4pu6rlu	543	12	damage	damage	NN
cord-353633-a4pu6rlu	543	13	in	in	IN
cord-353633-a4pu6rlu	543	14	hyperlipidemia	hyperlipidemia	NN
cord-353633-a4pu6rlu	543	15	-	-	HYPH
cord-353633-a4pu6rlu	543	16	prone	prone	JJ
cord-353633-a4pu6rlu	543	17	ApoE	ApoE	NNS
cord-353633-a4pu6rlu	543	18	-	-	HYPH
cord-353633-a4pu6rlu	543	19	null	null	JJ
cord-353633-a4pu6rlu	543	20	mice	mouse	NNS
cord-353633-a4pu6rlu	543	21	Protection	protection	NN
cord-353633-a4pu6rlu	543	22	from	from	IN
cord-353633-a4pu6rlu	543	23	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	543	24	lipid	lipid	NN
cord-353633-a4pu6rlu	543	25	accumulation	accumulation	NN
cord-353633-a4pu6rlu	543	26	and	and	CC
cord-353633-a4pu6rlu	543	27	inflammation	inflammation	NN
cord-353633-a4pu6rlu	543	28	by	by	IN
cord-353633-a4pu6rlu	543	29	genetic	genetic	JJ
cord-353633-a4pu6rlu	543	30	ablation	ablation	NN
cord-353633-a4pu6rlu	543	31	of	of	IN
cord-353633-a4pu6rlu	543	32	5-lipoxygenase	5-lipoxygenase	CD
cord-353633-a4pu6rlu	543	33	LTB4	LTB4	NNP
cord-353633-a4pu6rlu	543	34	promotes	promote	VBZ
cord-353633-a4pu6rlu	543	35	insulin	insulin	NN
cord-353633-a4pu6rlu	543	36	resistance	resistance	NN
cord-353633-a4pu6rlu	543	37	in	in	IN
cord-353633-a4pu6rlu	543	38	obese	obese	JJ
cord-353633-a4pu6rlu	543	39	mice	mouse	NNS
cord-353633-a4pu6rlu	543	40	by	by	IN
cord-353633-a4pu6rlu	543	41	acting	act	VBG
cord-353633-a4pu6rlu	543	42	on	on	IN
cord-353633-a4pu6rlu	543	43	macrophages	macrophage	NNS
cord-353633-a4pu6rlu	543	44	,	,	,
cord-353633-a4pu6rlu	543	45	hepatocytes	hepatocyte	NNS
cord-353633-a4pu6rlu	543	46	and	and	CC
cord-353633-a4pu6rlu	543	47	myocytes	myocyte	VBD
cord-353633-a4pu6rlu	543	48	Posttreatment	Posttreatment	NNP
cord-353633-a4pu6rlu	543	49	with	with	IN
cord-353633-a4pu6rlu	543	50	Protectin	Protectin	NNP
cord-353633-a4pu6rlu	543	51	DX	DX	NNP
cord-353633-a4pu6rlu	544	1	ameliorates	ameliorate	VBZ
cord-353633-a4pu6rlu	544	2	bleomycin	bleomycin	NN
cord-353633-a4pu6rlu	544	3	-	-	HYPH
cord-353633-a4pu6rlu	544	4	induced	induce	VBN
cord-353633-a4pu6rlu	544	5	pulmonary	pulmonary	JJ
cord-353633-a4pu6rlu	544	6	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	544	7	and	and	CC
cord-353633-a4pu6rlu	544	8	lung	lung	NN
cord-353633-a4pu6rlu	544	9	dysfunction	dysfunction	NN
cord-353633-a4pu6rlu	544	10	in	in	IN
cord-353633-a4pu6rlu	544	11	mice	mouse	NNS
cord-353633-a4pu6rlu	545	1	17(R)-resolvin	17(R)-resolvin	NNP
cord-353633-a4pu6rlu	545	2	D1	D1	NNP
cord-353633-a4pu6rlu	545	3	ameliorates	ameliorate	VBZ
cord-353633-a4pu6rlu	545	4	bleomycin	bleomycin	NN
cord-353633-a4pu6rlu	545	5	-	-	HYPH
cord-353633-a4pu6rlu	545	6	induced	induce	VBN
cord-353633-a4pu6rlu	545	7	pulmonary	pulmonary	JJ
cord-353633-a4pu6rlu	545	8	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	545	9	in	in	IN
cord-353633-a4pu6rlu	545	10	mice	mouse	NNS
cord-353633-a4pu6rlu	546	1	Proresolving	proresolving	NN
cord-353633-a4pu6rlu	546	2	actions	action	NNS
cord-353633-a4pu6rlu	546	3	of	of	IN
cord-353633-a4pu6rlu	546	4	a	a	DT
cord-353633-a4pu6rlu	546	5	new	new	JJ
cord-353633-a4pu6rlu	546	6	resolvin	resolvin	NNP
cord-353633-a4pu6rlu	546	7	D1	D1	NNP
cord-353633-a4pu6rlu	546	8	analog	analog	NN
cord-353633-a4pu6rlu	546	9	mimetic	mimetic	NN
cord-353633-a4pu6rlu	546	10	qualifies	qualify	VBZ
cord-353633-a4pu6rlu	546	11	as	as	IN
cord-353633-a4pu6rlu	546	12	an	an	DT
cord-353633-a4pu6rlu	546	13	immunoresolvent	immunoresolvent	NN
cord-353633-a4pu6rlu	546	14	Essentials	Essentials	NNPS
cord-353633-a4pu6rlu	546	15	of	of	IN
cord-353633-a4pu6rlu	546	16	Glycobiology	Glycobiology	NNP
cord-353633-a4pu6rlu	546	17	.	.	.
cord-353633-a4pu6rlu	547	1	Cold	Cold	NNP
cord-353633-a4pu6rlu	547	2	Spring	Spring	NNP
cord-353633-a4pu6rlu	547	3	Harbor	Harbor	NNP
cord-353633-a4pu6rlu	547	4	(	(	-LRB-
cord-353633-a4pu6rlu	547	5	NY)2015	NY)2015	NNP
cord-353633-a4pu6rlu	547	6	.	.	.
cord-353633-a4pu6rlu	548	1	p	p	LS
cord-353633-a4pu6rlu	548	2	Essentials	Essentials	NNPS
cord-353633-a4pu6rlu	548	3	of	of	IN
cord-353633-a4pu6rlu	548	4	Glycobiology	Glycobiology	NNP
cord-353633-a4pu6rlu	548	5	.	.	.
cord-353633-a4pu6rlu	549	1	Cold	Cold	NNP
cord-353633-a4pu6rlu	549	2	Spring	Spring	NNP
cord-353633-a4pu6rlu	549	3	Harbor	Harbor	NNP
cord-353633-a4pu6rlu	549	4	(	(	-LRB-
cord-353633-a4pu6rlu	549	5	NY)2015	NY)2015	NNP
cord-353633-a4pu6rlu	549	6	.	.	.
cord-353633-a4pu6rlu	550	1	p	p	LS
cord-353633-a4pu6rlu	550	2	Glycosylation	Glycosylation	NNP
cord-353633-a4pu6rlu	550	3	in	in	IN
cord-353633-a4pu6rlu	550	4	health	health	NN
cord-353633-a4pu6rlu	550	5	and	and	CC
cord-353633-a4pu6rlu	550	6	disease	disease	NN
cord-353633-a4pu6rlu	550	7	Glycans	Glycans	NNPS
cord-353633-a4pu6rlu	550	8	in	in	IN
cord-353633-a4pu6rlu	550	9	Acquired	Acquired	NNP
cord-353633-a4pu6rlu	550	10	Human	Human	NNP
cord-353633-a4pu6rlu	550	11	Diseases	Diseases	NNPS
cord-353633-a4pu6rlu	551	1	Glycosylation	Glycosylation	NNP
cord-353633-a4pu6rlu	551	2	Changes	change	VBZ
cord-353633-a4pu6rlu	551	3	in	in	IN
cord-353633-a4pu6rlu	551	4	Cancer	Cancer	NNP
cord-353633-a4pu6rlu	551	5	Sialic	Sialic	NNP
cord-353633-a4pu6rlu	551	6	Acids	Acids	NNPS
cord-353633-a4pu6rlu	551	7	and	and	CC
cord-353633-a4pu6rlu	551	8	Other	Other	NNP
cord-353633-a4pu6rlu	551	9	Nonulosonic	Nonulosonic	NNP
cord-353633-a4pu6rlu	551	10	Acids	Acids	NNPS
cord-353633-a4pu6rlu	551	11	Serum	Serum	NNP
cord-353633-a4pu6rlu	551	12	Sialic	Sialic	NNP
cord-353633-a4pu6rlu	551	13	Acid	acid	NN
cord-353633-a4pu6rlu	551	14	Level	level	NN
cord-353633-a4pu6rlu	551	15	Is	be	VBZ
cord-353633-a4pu6rlu	551	16	Significantly	significantly	RB
cord-353633-a4pu6rlu	551	17	Associated	associate	VBN
cord-353633-a4pu6rlu	551	18	with	with	IN
cord-353633-a4pu6rlu	551	19	Nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	551	20	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	551	21	Liver	Liver	NNP
cord-353633-a4pu6rlu	551	22	Disease	Disease	NNP
cord-353633-a4pu6rlu	551	23	in	in	IN
cord-353633-a4pu6rlu	551	24	a	a	DT
cord-353633-a4pu6rlu	551	25	Nonobese	Nonobese	NNP
cord-353633-a4pu6rlu	551	26	Chinese	Chinese	NNP
cord-353633-a4pu6rlu	551	27	Population	population	NN
cord-353633-a4pu6rlu	551	28	:	:	:
cord-353633-a4pu6rlu	552	1	A	a	DT
cord-353633-a4pu6rlu	552	2	Cross	Cross	NNP
cord-353633-a4pu6rlu	552	3	-	-	NNP
cord-353633-a4pu6rlu	552	4	Sectional	Sectional	NNP
cord-353633-a4pu6rlu	552	5	Study	Study	NNP
cord-353633-a4pu6rlu	552	6	Association	Association	NNP
cord-353633-a4pu6rlu	552	7	between	between	IN
cord-353633-a4pu6rlu	552	8	Serum	Serum	NNP
cord-353633-a4pu6rlu	552	9	Sialic	Sialic	NNP
cord-353633-a4pu6rlu	552	10	Acid	Acid	NNP
cord-353633-a4pu6rlu	552	11	Levels	Levels	NNPS
cord-353633-a4pu6rlu	552	12	and	and	CC
cord-353633-a4pu6rlu	552	13	Nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	552	14	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	552	15	Liver	Liver	NNP
cord-353633-a4pu6rlu	552	16	Disease	Disease	NNP
cord-353633-a4pu6rlu	552	17	:	:	:
cord-353633-a4pu6rlu	553	1	A	a	DT
cord-353633-a4pu6rlu	553	2	Cross	Cross	NNP
cord-353633-a4pu6rlu	553	3	-	-	NNP
cord-353633-a4pu6rlu	553	4	Sectional	Sectional	NNP
cord-353633-a4pu6rlu	553	5	Study	Study	NNP
cord-353633-a4pu6rlu	553	6	Unmasking	Unmasking	NNP
cord-353633-a4pu6rlu	553	7	Fucosylation	Fucosylation	NNP
cord-353633-a4pu6rlu	553	8	:	:	:
cord-353633-a4pu6rlu	553	9	from	from	IN
cord-353633-a4pu6rlu	553	10	Cell	cell	NN
cord-353633-a4pu6rlu	553	11	Adhesion	Adhesion	NNP
cord-353633-a4pu6rlu	553	12	to	to	IN
cord-353633-a4pu6rlu	553	13	Immune	Immune	NNP
cord-353633-a4pu6rlu	553	14	System	System	NNP
cord-353633-a4pu6rlu	553	15	Regulation	Regulation	NNP
cord-353633-a4pu6rlu	553	16	and	and	CC
cord-353633-a4pu6rlu	553	17	Diseases	Diseases	NNPS
cord-353633-a4pu6rlu	553	18	A	a	DT
cord-353633-a4pu6rlu	553	19	novel	novel	JJ
cord-353633-a4pu6rlu	553	20	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	553	21	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	553	22	method	method	NN
cord-353633-a4pu6rlu	553	23	for	for	IN
cord-353633-a4pu6rlu	553	24	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	553	25	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	553	26	using	use	VBG
cord-353633-a4pu6rlu	553	27	two	two	CD
cord-353633-a4pu6rlu	553	28	glycobiomarkers	glycobiomarker	NNS
cord-353633-a4pu6rlu	553	29	Inhibition	Inhibition	NNP
cord-353633-a4pu6rlu	553	30	of	of	IN
cord-353633-a4pu6rlu	553	31	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	553	32	reshapes	reshape	VBZ
cord-353633-a4pu6rlu	553	33	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	553	34	macrophages	macrophage	NNS
cord-353633-a4pu6rlu	553	35	and	and	CC
cord-353633-a4pu6rlu	553	36	suppresses	suppress	VBZ
cord-353633-a4pu6rlu	553	37	type	type	NN
cord-353633-a4pu6rlu	553	38	II	II	NNP
cord-353633-a4pu6rlu	553	39	collagen	collagen	NN
cord-353633-a4pu6rlu	553	40	-	-	HYPH
cord-353633-a4pu6rlu	553	41	induced	induce	VBN
cord-353633-a4pu6rlu	553	42	arthritis	arthritis	NN
cord-353633-a4pu6rlu	553	43	Inhibition	inhibition	NN
cord-353633-a4pu6rlu	553	44	of	of	IN
cord-353633-a4pu6rlu	553	45	fucosylation	fucosylation	NN
cord-353633-a4pu6rlu	553	46	by	by	IN
cord-353633-a4pu6rlu	553	47	2-fluorofucose	2-fluorofucose	CD
cord-353633-a4pu6rlu	554	1	suppresses	suppress	VBZ
cord-353633-a4pu6rlu	554	2	human	human	JJ
cord-353633-a4pu6rlu	554	3	liver	liver	NN
cord-353633-a4pu6rlu	554	4	cancer	cancer	NN
cord-353633-a4pu6rlu	554	5	HepG2	HepG2	NNP
cord-353633-a4pu6rlu	554	6	cell	cell	NN
cord-353633-a4pu6rlu	554	7	proliferation	proliferation	NN
cord-353633-a4pu6rlu	554	8	and	and	CC
cord-353633-a4pu6rlu	554	9	migration	migration	NN
cord-353633-a4pu6rlu	554	10	as	as	RB
cord-353633-a4pu6rlu	554	11	well	well	RB
cord-353633-a4pu6rlu	554	12	as	as	IN
cord-353633-a4pu6rlu	554	13	tumor	tumor	NN
cord-353633-a4pu6rlu	554	14	formation	formation	NN
cord-353633-a4pu6rlu	554	15	Performance	performance	NN
cord-353633-a4pu6rlu	554	16	of	of	IN
cord-353633-a4pu6rlu	554	17	Plasma	Plasma	NNP
cord-353633-a4pu6rlu	554	18	Biomarkers	Biomarkers	NNPS
cord-353633-a4pu6rlu	554	19	and	and	CC
cord-353633-a4pu6rlu	554	20	Diagnostic	Diagnostic	NNP
cord-353633-a4pu6rlu	554	21	Panels	Panels	NNPS
cord-353633-a4pu6rlu	554	22	for	for	IN
cord-353633-a4pu6rlu	554	23	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	554	24	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	554	25	and	and	CC
cord-353633-a4pu6rlu	554	26	Advanced	Advanced	NNP
cord-353633-a4pu6rlu	554	27	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	554	28	in	in	IN
cord-353633-a4pu6rlu	554	29	Patients	patient	NNS
cord-353633-a4pu6rlu	555	1	With	with	IN
cord-353633-a4pu6rlu	555	2	Type	type	NN
cord-353633-a4pu6rlu	555	3	2	2	CD
cord-353633-a4pu6rlu	555	4	Diabetes	diabetes	NN
cord-353633-a4pu6rlu	555	5	Performance	performance	NN
cord-353633-a4pu6rlu	555	6	of	of	IN
cord-353633-a4pu6rlu	555	7	the	the	DT
cord-353633-a4pu6rlu	555	8	SteatoTest	SteatoTest	NNP
cord-353633-a4pu6rlu	555	9	,	,	,
cord-353633-a4pu6rlu	555	10	ActiTest	ActiTest	NNP
cord-353633-a4pu6rlu	555	11	,	,	,
cord-353633-a4pu6rlu	555	12	NashTest	NashTest	NNP
cord-353633-a4pu6rlu	555	13	and	and	CC
cord-353633-a4pu6rlu	555	14	FibroTest	FibroTest	NNP
cord-353633-a4pu6rlu	555	15	in	in	IN
cord-353633-a4pu6rlu	555	16	a	a	DT
cord-353633-a4pu6rlu	555	17	multiethnic	multiethnic	JJ
cord-353633-a4pu6rlu	555	18	cohort	cohort	NN
cord-353633-a4pu6rlu	555	19	of	of	IN
cord-353633-a4pu6rlu	555	20	patients	patient	NNS
cord-353633-a4pu6rlu	555	21	with	with	IN
cord-353633-a4pu6rlu	555	22	type	type	NN
cord-353633-a4pu6rlu	555	23	2	2	CD
cord-353633-a4pu6rlu	555	24	diabetes	diabetes	NN
cord-353633-a4pu6rlu	555	25	mellitus	mellitus	NN
cord-353633-a4pu6rlu	555	26	Change	change	NN
cord-353633-a4pu6rlu	555	27	in	in	IN
cord-353633-a4pu6rlu	555	28	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	555	29	fat	fat	NN
cord-353633-a4pu6rlu	555	30	content	content	NN
cord-353633-a4pu6rlu	555	31	measured	measure	VBN
cord-353633-a4pu6rlu	555	32	by	by	IN
cord-353633-a4pu6rlu	555	33	MRI	MRI	NNP
cord-353633-a4pu6rlu	555	34	does	do	VBZ
cord-353633-a4pu6rlu	555	35	not	not	RB
cord-353633-a4pu6rlu	555	36	predict	predict	VB
cord-353633-a4pu6rlu	555	37	treatment	treatment	NN
cord-353633-a4pu6rlu	555	38	-	-	HYPH
cord-353633-a4pu6rlu	555	39	induced	induce	VBN
cord-353633-a4pu6rlu	555	40	histological	histological	JJ
cord-353633-a4pu6rlu	555	41	improvement	improvement	NN
cord-353633-a4pu6rlu	555	42	of	of	IN
cord-353633-a4pu6rlu	555	43	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	555	44	Performance	Performance	NNP
cord-353633-a4pu6rlu	555	45	of	of	IN
cord-353633-a4pu6rlu	555	46	biomarkers	biomarkers	NNPS
cord-353633-a4pu6rlu	555	47	FibroTest	FibroTest	NNP
cord-353633-a4pu6rlu	555	48	,	,	,
cord-353633-a4pu6rlu	555	49	ActiTest	ActiTest	NNP
cord-353633-a4pu6rlu	555	50	,	,	,
cord-353633-a4pu6rlu	555	51	SteatoTest	SteatoTest	NNP
cord-353633-a4pu6rlu	555	52	,	,	,
cord-353633-a4pu6rlu	555	53	and	and	CC
cord-353633-a4pu6rlu	555	54	NashTest	NashTest	NNP
cord-353633-a4pu6rlu	555	55	in	in	IN
cord-353633-a4pu6rlu	555	56	patients	patient	NNS
cord-353633-a4pu6rlu	555	57	with	with	IN
cord-353633-a4pu6rlu	555	58	severe	severe	JJ
cord-353633-a4pu6rlu	555	59	obesity	obesity	NN
cord-353633-a4pu6rlu	555	60	:	:	:
cord-353633-a4pu6rlu	556	1	meta	meta	NNP
cord-353633-a4pu6rlu	556	2	analysis	analysis	NN
cord-353633-a4pu6rlu	556	3	of	of	IN
cord-353633-a4pu6rlu	556	4	individual	individual	JJ
cord-353633-a4pu6rlu	556	5	patient	patient	NN
cord-353633-a4pu6rlu	556	6	data	datum	NNS
cord-353633-a4pu6rlu	556	7	ADAPT	adapt	VBP
cord-353633-a4pu6rlu	556	8	:	:	:
cord-353633-a4pu6rlu	557	1	An	an	DT
cord-353633-a4pu6rlu	557	2	Algorithm	algorithm	NN
cord-353633-a4pu6rlu	558	1	Incorporating	incorporate	VBG
cord-353633-a4pu6rlu	558	2	PRO	pro	JJ
cord-353633-a4pu6rlu	558	3	-	-	JJ
cord-353633-a4pu6rlu	558	4	C3	c3	JJ
cord-353633-a4pu6rlu	559	1	Accurately	accurately	RB
cord-353633-a4pu6rlu	559	2	Identifies	identify	VBZ
cord-353633-a4pu6rlu	559	3	Patients	patient	NNS
cord-353633-a4pu6rlu	559	4	With	with	IN
cord-353633-a4pu6rlu	559	5	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	559	6	and	and	CC
cord-353633-a4pu6rlu	559	7	Advanced	Advanced	NNP
cord-353633-a4pu6rlu	559	8	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	559	9	Comparison	Comparison	NNP
cord-353633-a4pu6rlu	559	10	of	of	IN
cord-353633-a4pu6rlu	559	11	laboratory	laboratory	NN
cord-353633-a4pu6rlu	559	12	tests	test	NNS
cord-353633-a4pu6rlu	559	13	,	,	,
cord-353633-a4pu6rlu	559	14	ultrasound	ultrasound	NN
cord-353633-a4pu6rlu	559	15	,	,	,
cord-353633-a4pu6rlu	559	16	or	or	CC
cord-353633-a4pu6rlu	559	17	magnetic	magnetic	JJ
cord-353633-a4pu6rlu	559	18	resonance	resonance	NN
cord-353633-a4pu6rlu	559	19	elastography	elastography	NN
cord-353633-a4pu6rlu	559	20	to	to	TO
cord-353633-a4pu6rlu	559	21	detect	detect	VB
cord-353633-a4pu6rlu	559	22	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	559	23	in	in	IN
cord-353633-a4pu6rlu	559	24	patients	patient	NNS
cord-353633-a4pu6rlu	559	25	with	with	IN
cord-353633-a4pu6rlu	559	26	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	559	27	fatty	fatty	JJ
cord-353633-a4pu6rlu	559	28	liver	liver	NN
cord-353633-a4pu6rlu	559	29	disease	disease	NN
cord-353633-a4pu6rlu	559	30	:	:	:
cord-353633-a4pu6rlu	559	31	A	a	DT
cord-353633-a4pu6rlu	559	32	meta	meta	JJ
cord-353633-a4pu6rlu	559	33	-	-	HYPH
cord-353633-a4pu6rlu	559	34	analysis	analysis	NN
cord-353633-a4pu6rlu	559	35	Enhanced	enhance	VBN
cord-353633-a4pu6rlu	559	36	liver	liver	NN
cord-353633-a4pu6rlu	559	37	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	559	38	test	test	NN
cord-353633-a4pu6rlu	559	39	for	for	IN
cord-353633-a4pu6rlu	559	40	the	the	DT
cord-353633-a4pu6rlu	559	41	non	non	JJ
cord-353633-a4pu6rlu	559	42	-	-	JJ
cord-353633-a4pu6rlu	559	43	invasive	invasive	JJ
cord-353633-a4pu6rlu	559	44	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	559	45	of	of	IN
cord-353633-a4pu6rlu	559	46	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	559	47	in	in	IN
cord-353633-a4pu6rlu	559	48	patients	patient	NNS
cord-353633-a4pu6rlu	559	49	with	with	IN
cord-353633-a4pu6rlu	559	50	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	559	51	:	:	:
cord-353633-a4pu6rlu	559	52	A	a	DT
cord-353633-a4pu6rlu	559	53	systematic	systematic	JJ
cord-353633-a4pu6rlu	559	54	review	review	NN
cord-353633-a4pu6rlu	559	55	and	and	CC
cord-353633-a4pu6rlu	559	56	meta	meta	NNP
cord-353633-a4pu6rlu	559	57	-	-	HYPH
cord-353633-a4pu6rlu	559	58	analysis	analysis	NN
cord-353633-a4pu6rlu	559	59	Accuracy	accuracy	NN
cord-353633-a4pu6rlu	559	60	of	of	IN
cord-353633-a4pu6rlu	559	61	FibroScan	FibroScan	NNP
cord-353633-a4pu6rlu	559	62	Controlled	Controlled	NNP
cord-353633-a4pu6rlu	559	63	Attenuation	Attenuation	NNP
cord-353633-a4pu6rlu	559	64	Parameter	Parameter	NNP
cord-353633-a4pu6rlu	559	65	and	and	CC
cord-353633-a4pu6rlu	559	66	Liver	Liver	NNP
cord-353633-a4pu6rlu	559	67	Stiffness	Stiffness	NNP
cord-353633-a4pu6rlu	559	68	Measurement	Measurement	NNP
cord-353633-a4pu6rlu	559	69	in	in	IN
cord-353633-a4pu6rlu	559	70	Assessing	Assessing	NNP
cord-353633-a4pu6rlu	559	71	Steatosis	Steatosis	NNP
cord-353633-a4pu6rlu	559	72	and	and	CC
cord-353633-a4pu6rlu	559	73	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	559	74	in	in	IN
cord-353633-a4pu6rlu	559	75	Patients	Patients	NNP
cord-353633-a4pu6rlu	559	76	With	with	IN
cord-353633-a4pu6rlu	559	77	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	559	78	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	559	79	Liver	Liver	NNP
cord-353633-a4pu6rlu	559	80	Disease	Disease	NNP
cord-353633-a4pu6rlu	559	81	Diagnostic	Diagnostic	NNP
cord-353633-a4pu6rlu	559	82	Accuracy	Accuracy	NNP
cord-353633-a4pu6rlu	559	83	of	of	IN
cord-353633-a4pu6rlu	559	84	Noninvasive	Noninvasive	NNP
cord-353633-a4pu6rlu	559	85	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	559	86	Models	Models	NNPS
cord-353633-a4pu6rlu	559	87	to	to	TO
cord-353633-a4pu6rlu	559	88	Detect	detect	VB
cord-353633-a4pu6rlu	559	89	Change	change	NN
cord-353633-a4pu6rlu	559	90	in	in	IN
cord-353633-a4pu6rlu	559	91	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	559	92	Stage	Stage	NNP
cord-353633-a4pu6rlu	559	93	Noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	559	94	Tests	test	NNS
cord-353633-a4pu6rlu	559	95	Accurately	accurately	RB
cord-353633-a4pu6rlu	559	96	Identify	identify	VB
cord-353633-a4pu6rlu	559	97	Advanced	Advanced	NNP
cord-353633-a4pu6rlu	559	98	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	559	99	due	due	IN
cord-353633-a4pu6rlu	559	100	to	to	IN
cord-353633-a4pu6rlu	559	101	NASH	NASH	NNP
cord-353633-a4pu6rlu	559	102	:	:	:
cord-353633-a4pu6rlu	559	103	Baseline	Baseline	NNP
cord-353633-a4pu6rlu	559	104	Data	Data	NNP
cord-353633-a4pu6rlu	559	105	From	from	IN
cord-353633-a4pu6rlu	559	106	the	the	DT
cord-353633-a4pu6rlu	559	107	STELLAR	STELLAR	NNP
cord-353633-a4pu6rlu	559	108	Trials	Trials	NNPS
cord-353633-a4pu6rlu	559	109	Genetic	genetic	JJ
cord-353633-a4pu6rlu	559	110	signatures	signature	NNS
cord-353633-a4pu6rlu	559	111	in	in	IN
cord-353633-a4pu6rlu	559	112	choline	choline	NN
cord-353633-a4pu6rlu	559	113	and	and	CC
cord-353633-a4pu6rlu	559	114	1-carbon	1-carbon	CD
cord-353633-a4pu6rlu	559	115	metabolism	metabolism	NN
cord-353633-a4pu6rlu	559	116	are	be	VBP
cord-353633-a4pu6rlu	559	117	associated	associate	VBN
cord-353633-a4pu6rlu	559	118	with	with	IN
cord-353633-a4pu6rlu	559	119	the	the	DT
cord-353633-a4pu6rlu	559	120	severity	severity	NN
cord-353633-a4pu6rlu	559	121	of	of	IN
cord-353633-a4pu6rlu	559	122	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	559	123	steatosis	steatosis	NN
cord-353633-a4pu6rlu	559	124	Efficacy	efficacy	NN
cord-353633-a4pu6rlu	559	125	of	of	IN
cord-353633-a4pu6rlu	559	126	serum	serum	NN
cord-353633-a4pu6rlu	559	127	miRNA	miRNA	NNP
cord-353633-a4pu6rlu	559	128	test	test	NN
cord-353633-a4pu6rlu	559	129	as	as	IN
cord-353633-a4pu6rlu	559	130	a	a	DT
cord-353633-a4pu6rlu	559	131	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	559	132	method	method	NN
cord-353633-a4pu6rlu	559	133	to	to	TO
cord-353633-a4pu6rlu	559	134	diagnose	diagnose	VB
cord-353633-a4pu6rlu	559	135	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	559	136	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	559	137	:	:	:
cord-353633-a4pu6rlu	559	138	a	a	DT
cord-353633-a4pu6rlu	559	139	systematic	systematic	JJ
cord-353633-a4pu6rlu	559	140	review	review	NN
cord-353633-a4pu6rlu	559	141	and	and	CC
cord-353633-a4pu6rlu	559	142	meta	meta	NNP
cord-353633-a4pu6rlu	559	143	-	-	HYPH
cord-353633-a4pu6rlu	559	144	analysis	analysis	NNP
cord-353633-a4pu6rlu	559	145	Serum	Serum	NNP
cord-353633-a4pu6rlu	559	146	proteomic	proteomic	JJ
cord-353633-a4pu6rlu	559	147	analysis	analysis	NN
cord-353633-a4pu6rlu	559	148	revealed	reveal	VBD
cord-353633-a4pu6rlu	559	149	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	559	150	value	value	NN
cord-353633-a4pu6rlu	559	151	of	of	IN
cord-353633-a4pu6rlu	559	152	hemoglobin	hemoglobin	NN
cord-353633-a4pu6rlu	559	153	for	for	IN
cord-353633-a4pu6rlu	559	154	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	559	155	fatty	fatty	JJ
cord-353633-a4pu6rlu	559	156	liver	liver	NN
cord-353633-a4pu6rlu	559	157	disease	disease	NN
cord-353633-a4pu6rlu	559	158	Proteomic	Proteomic	NNP
cord-353633-a4pu6rlu	559	159	analysis	analysis	NN
cord-353633-a4pu6rlu	559	160	of	of	IN
cord-353633-a4pu6rlu	559	161	serum	serum	NN
cord-353633-a4pu6rlu	559	162	in	in	IN
cord-353633-a4pu6rlu	559	163	patients	patient	NNS
cord-353633-a4pu6rlu	559	164	with	with	IN
cord-353633-a4pu6rlu	559	165	non	non	JJ
cord-353633-a4pu6rlu	559	166	-	-	JJ
cord-353633-a4pu6rlu	559	167	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	559	168	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	559	169	using	use	VBG
cord-353633-a4pu6rlu	559	170	matrix	matrix	NN
cord-353633-a4pu6rlu	559	171	-	-	HYPH
cord-353633-a4pu6rlu	559	172	assisted	assist	VBN
cord-353633-a4pu6rlu	559	173	laser	laser	NN
cord-353633-a4pu6rlu	559	174	desorption	desorption	NN
cord-353633-a4pu6rlu	559	175	ionization	ionization	NN
cord-353633-a4pu6rlu	559	176	time	time	NN
cord-353633-a4pu6rlu	559	177	-	-	HYPH
cord-353633-a4pu6rlu	559	178	of	of	IN
cord-353633-a4pu6rlu	559	179	-	-	HYPH
cord-353633-a4pu6rlu	559	180	flight	flight	NN
cord-353633-a4pu6rlu	559	181	mass	mass	NN
cord-353633-a4pu6rlu	559	182	spectrometry	spectrometry	NN
cord-353633-a4pu6rlu	559	183	Serum	serum	NN
cord-353633-a4pu6rlu	559	184	proteome	proteome	NN
cord-353633-a4pu6rlu	559	185	of	of	IN
cord-353633-a4pu6rlu	559	186	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	559	187	fatty	fatty	JJ
cord-353633-a4pu6rlu	559	188	liver	liver	NN
cord-353633-a4pu6rlu	559	189	disease	disease	NN
cord-353633-a4pu6rlu	559	190	:	:	:
cord-353633-a4pu6rlu	559	191	a	a	DT
cord-353633-a4pu6rlu	559	192	multimodal	multimodal	NN
cord-353633-a4pu6rlu	559	193	approach	approach	NN
cord-353633-a4pu6rlu	559	194	to	to	IN
cord-353633-a4pu6rlu	559	195	discovery	discovery	NN
cord-353633-a4pu6rlu	559	196	of	of	IN
cord-353633-a4pu6rlu	559	197	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	559	198	of	of	IN
cord-353633-a4pu6rlu	559	199	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	559	200	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	559	201	Phosphoproteomic	Phosphoproteomic	NNP
cord-353633-a4pu6rlu	559	202	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	559	203	predicting	predict	VBG
cord-353633-a4pu6rlu	559	204	histologic	histologic	JJ
cord-353633-a4pu6rlu	559	205	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	559	206	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	559	207	and	and	CC
cord-353633-a4pu6rlu	560	1	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	560	2	Mapping	Mapping	NNP
cord-353633-a4pu6rlu	560	3	of	of	IN
cord-353633-a4pu6rlu	560	4	the	the	DT
cord-353633-a4pu6rlu	560	5	circulating	circulate	VBG
cord-353633-a4pu6rlu	560	6	metabolome	metabolome	NN
cord-353633-a4pu6rlu	560	7	reveals	reveal	VBZ
cord-353633-a4pu6rlu	560	8	alpha	alpha	NN
cord-353633-a4pu6rlu	560	9	-	-	HYPH
cord-353633-a4pu6rlu	560	10	ketoglutarate	ketoglutarate	NNP
cord-353633-a4pu6rlu	560	11	as	as	IN
cord-353633-a4pu6rlu	560	12	a	a	DT
cord-353633-a4pu6rlu	560	13	predictor	predictor	NN
cord-353633-a4pu6rlu	560	14	of	of	IN
cord-353633-a4pu6rlu	560	15	morbid	morbid	JJ
cord-353633-a4pu6rlu	560	16	obesity	obesity	NN
cord-353633-a4pu6rlu	560	17	-	-	HYPH
cord-353633-a4pu6rlu	560	18	associated	associate	VBN
cord-353633-a4pu6rlu	560	19	non	non	JJ
cord-353633-a4pu6rlu	560	20	-	-	JJ
cord-353633-a4pu6rlu	560	21	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	560	22	fatty	fatty	JJ
cord-353633-a4pu6rlu	560	23	liver	liver	NN
cord-353633-a4pu6rlu	560	24	disease	disease	NN
cord-353633-a4pu6rlu	560	25	Prediction	Prediction	NNP
cord-353633-a4pu6rlu	560	26	of	of	IN
cord-353633-a4pu6rlu	560	27	non	non	JJ
cord-353633-a4pu6rlu	560	28	-	-	JJ
cord-353633-a4pu6rlu	560	29	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	560	30	fatty	fatty	JJ
cord-353633-a4pu6rlu	560	31	-	-	HYPH
cord-353633-a4pu6rlu	560	32	liver	liver	NN
cord-353633-a4pu6rlu	560	33	disease	disease	NN
cord-353633-a4pu6rlu	560	34	and	and	CC
cord-353633-a4pu6rlu	560	35	liver	liver	NN
cord-353633-a4pu6rlu	560	36	fat	fat	NN
cord-353633-a4pu6rlu	560	37	content	content	NN
cord-353633-a4pu6rlu	560	38	by	by	IN
cord-353633-a4pu6rlu	560	39	serum	serum	NN
cord-353633-a4pu6rlu	560	40	molecular	molecular	JJ
cord-353633-a4pu6rlu	560	41	lipids	lipid	NNS
cord-353633-a4pu6rlu	560	42	Obesity	obesity	NN
cord-353633-a4pu6rlu	560	43	-	-	HYPH
cord-353633-a4pu6rlu	560	44	dependent	dependent	JJ
cord-353633-a4pu6rlu	560	45	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	560	46	signatures	signature	NNS
cord-353633-a4pu6rlu	560	47	associated	associate	VBN
cord-353633-a4pu6rlu	560	48	with	with	IN
cord-353633-a4pu6rlu	560	49	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	560	50	fatty	fatty	JJ
cord-353633-a4pu6rlu	560	51	liver	liver	NN
cord-353633-a4pu6rlu	560	52	disease	disease	NN
cord-353633-a4pu6rlu	560	53	progression	progression	NN
cord-353633-a4pu6rlu	560	54	Mass	Mass	NNP
cord-353633-a4pu6rlu	560	55	spectrometric	spectrometric	JJ
cord-353633-a4pu6rlu	560	56	profiling	profiling	NN
cord-353633-a4pu6rlu	560	57	of	of	IN
cord-353633-a4pu6rlu	560	58	oxidized	oxidized	JJ
cord-353633-a4pu6rlu	560	59	lipid	lipid	NN
cord-353633-a4pu6rlu	560	60	products	product	NNS
cord-353633-a4pu6rlu	560	61	in	in	IN
cord-353633-a4pu6rlu	560	62	human	human	JJ
cord-353633-a4pu6rlu	560	63	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	560	64	fatty	fatty	JJ
cord-353633-a4pu6rlu	560	65	liver	liver	NN
cord-353633-a4pu6rlu	560	66	disease	disease	NN
cord-353633-a4pu6rlu	560	67	and	and	CC
cord-353633-a4pu6rlu	560	68	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	560	69	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	560	70	Urinary	Urinary	NNP
cord-353633-a4pu6rlu	560	71	metabolomics	metabolomic	NNS
cord-353633-a4pu6rlu	560	72	analysis	analysis	NN
cord-353633-a4pu6rlu	560	73	identifies	identify	VBZ
cord-353633-a4pu6rlu	560	74	key	key	JJ
cord-353633-a4pu6rlu	560	75	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	560	76	of	of	IN
cord-353633-a4pu6rlu	560	77	different	different	JJ
cord-353633-a4pu6rlu	560	78	stages	stage	NNS
cord-353633-a4pu6rlu	560	79	of	of	IN
cord-353633-a4pu6rlu	560	80	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	560	81	fatty	fatty	JJ
cord-353633-a4pu6rlu	560	82	liver	liver	NN
cord-353633-a4pu6rlu	560	83	disease	disease	NN
cord-353633-a4pu6rlu	561	1	Serum	serum	NN
cord-353633-a4pu6rlu	561	2	C16:1n7	C16:1n7	NNP
cord-353633-a4pu6rlu	561	3	/	/	SYM
cord-353633-a4pu6rlu	561	4	C16:0	C16:0	NNP
cord-353633-a4pu6rlu	561	5	ratio	ratio	NN
cord-353633-a4pu6rlu	561	6	as	as	IN
cord-353633-a4pu6rlu	561	7	a	a	DT
cord-353633-a4pu6rlu	561	8	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	561	9	marker	marker	NN
cord-353633-a4pu6rlu	561	10	for	for	IN
cord-353633-a4pu6rlu	561	11	non	non	JJ
cord-353633-a4pu6rlu	561	12	-	-	JJ
cord-353633-a4pu6rlu	561	13	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	561	14	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	561	15	Fatty	fatty	JJ
cord-353633-a4pu6rlu	561	16	acids	acid	NNS
cord-353633-a4pu6rlu	561	17	in	in	IN
cord-353633-a4pu6rlu	561	18	non	non	JJ
cord-353633-a4pu6rlu	561	19	-	-	JJ
cord-353633-a4pu6rlu	561	20	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	561	21	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	561	22	:	:	:
cord-353633-a4pu6rlu	562	1	Focus	focus	VB
cord-353633-a4pu6rlu	562	2	on	on	IN
cord-353633-a4pu6rlu	562	3	pentadecanoic	pentadecanoic	NNP
cord-353633-a4pu6rlu	562	4	acid	acid	NN
cord-353633-a4pu6rlu	562	5	Accurate	accurate	JJ
cord-353633-a4pu6rlu	562	6	non	non	JJ
cord-353633-a4pu6rlu	562	7	-	-	JJ
cord-353633-a4pu6rlu	562	8	invasive	invasive	JJ
cord-353633-a4pu6rlu	562	9	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	562	10	and	and	CC
cord-353633-a4pu6rlu	562	11	staging	staging	NN
cord-353633-a4pu6rlu	562	12	of	of	IN
cord-353633-a4pu6rlu	562	13	non	non	JJ
cord-353633-a4pu6rlu	562	14	-	-	JJ
cord-353633-a4pu6rlu	562	15	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	562	16	fatty	fatty	JJ
cord-353633-a4pu6rlu	562	17	liver	liver	NN
cord-353633-a4pu6rlu	562	18	disease	disease	NN
cord-353633-a4pu6rlu	562	19	using	use	VBG
cord-353633-a4pu6rlu	562	20	the	the	DT
cord-353633-a4pu6rlu	562	21	urinary	urinary	JJ
cord-353633-a4pu6rlu	562	22	steroid	steroid	NN
cord-353633-a4pu6rlu	562	23	metabolome	metabolome	NNP
cord-353633-a4pu6rlu	562	24	Serum	Serum	NNP
cord-353633-a4pu6rlu	562	25	metabolomic	metabolomic	NN
cord-353633-a4pu6rlu	562	26	profile	profile	NN
cord-353633-a4pu6rlu	562	27	and	and	CC
cord-353633-a4pu6rlu	562	28	potential	potential	JJ
cord-353633-a4pu6rlu	562	29	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	562	30	for	for	IN
cord-353633-a4pu6rlu	562	31	severity	severity	NN
cord-353633-a4pu6rlu	562	32	of	of	IN
cord-353633-a4pu6rlu	562	33	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	562	34	in	in	IN
cord-353633-a4pu6rlu	562	35	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	562	36	fatty	fatty	JJ
cord-353633-a4pu6rlu	562	37	liver	liver	NN
cord-353633-a4pu6rlu	562	38	disease	disease	NN
cord-353633-a4pu6rlu	562	39	Lipidomic	Lipidomic	NNP
cord-353633-a4pu6rlu	562	40	-	-	HYPH
cord-353633-a4pu6rlu	562	41	based	base	VBN
cord-353633-a4pu6rlu	562	42	Analysis	Analysis	NNP
cord-353633-a4pu6rlu	562	43	of	of	IN
cord-353633-a4pu6rlu	562	44	Plasma	Plasma	NNP
cord-353633-a4pu6rlu	562	45	to	to	TO
cord-353633-a4pu6rlu	562	46	Diagnose	diagnose	VB
cord-353633-a4pu6rlu	562	47	Hepatocellular	Hepatocellular	NNP
cord-353633-a4pu6rlu	562	48	Ballooning	Ballooning	NNP
cord-353633-a4pu6rlu	562	49	in	in	IN
cord-353633-a4pu6rlu	562	50	Patients	patient	NNS
cord-353633-a4pu6rlu	562	51	with	with	IN
cord-353633-a4pu6rlu	562	52	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	562	53	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	562	54	Liver	Liver	NNP
cord-353633-a4pu6rlu	562	55	Disease	Disease	NNP
cord-353633-a4pu6rlu	562	56	:	:	:
cord-353633-a4pu6rlu	563	1	A	a	DT
cord-353633-a4pu6rlu	563	2	Multicenter	Multicenter	NNP
cord-353633-a4pu6rlu	563	3	Study	Study	NNP
cord-353633-a4pu6rlu	563	4	Use	Use	NNP
cord-353633-a4pu6rlu	563	5	of	of	IN
cord-353633-a4pu6rlu	563	6	non	non	JJ
cord-353633-a4pu6rlu	563	7	-	-	JJ
cord-353633-a4pu6rlu	563	8	invasive	invasive	JJ
cord-353633-a4pu6rlu	563	9	serum	serum	NN
cord-353633-a4pu6rlu	563	10	glycan	glycan	NN
cord-353633-a4pu6rlu	563	11	markers	marker	NNS
cord-353633-a4pu6rlu	563	12	to	to	TO
cord-353633-a4pu6rlu	563	13	distinguish	distinguish	VB
cord-353633-a4pu6rlu	563	14	non	non	JJ
cord-353633-a4pu6rlu	563	15	-	-	JJ
cord-353633-a4pu6rlu	563	16	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	563	17	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	563	18	from	from	IN
cord-353633-a4pu6rlu	563	19	simple	simple	JJ
cord-353633-a4pu6rlu	563	20	steatosis	steatosis	NN
cord-353633-a4pu6rlu	563	21	N	n	NN
cord-353633-a4pu6rlu	563	22	-	-	HYPH
cord-353633-a4pu6rlu	563	23	glycan	glycan	NN
cord-353633-a4pu6rlu	563	24	based	base	VBN
cord-353633-a4pu6rlu	563	25	biomarker	biomarker	NN
cord-353633-a4pu6rlu	563	26	distinguishing	distinguish	VBG
cord-353633-a4pu6rlu	563	27	non	non	JJ
cord-353633-a4pu6rlu	563	28	-	-	JJ
cord-353633-a4pu6rlu	563	29	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	563	30	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	563	31	from	from	IN
cord-353633-a4pu6rlu	563	32	steatosis	steatosis	NN
cord-353633-a4pu6rlu	563	33	independently	independently	RB
cord-353633-a4pu6rlu	563	34	of	of	IN
cord-353633-a4pu6rlu	563	35	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	563	36	Serum	Serum	NNP
cord-353633-a4pu6rlu	563	37	protein	protein	NN
cord-353633-a4pu6rlu	563	38	N	n	CD
cord-353633-a4pu6rlu	563	39	-	-	HYPH
cord-353633-a4pu6rlu	563	40	glycans	glycan	NNS
cord-353633-a4pu6rlu	563	41	profiling	profile	VBG
cord-353633-a4pu6rlu	563	42	for	for	IN
cord-353633-a4pu6rlu	563	43	the	the	DT
cord-353633-a4pu6rlu	563	44	discovery	discovery	NN
cord-353633-a4pu6rlu	563	45	of	of	IN
cord-353633-a4pu6rlu	563	46	potential	potential	JJ
cord-353633-a4pu6rlu	563	47	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	563	48	for	for	IN
cord-353633-a4pu6rlu	563	49	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	50	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	563	51	Use	Use	NNP
cord-353633-a4pu6rlu	563	52	of	of	IN
cord-353633-a4pu6rlu	563	53	Mac-2	Mac-2	NNP
cord-353633-a4pu6rlu	563	54	binding	bind	VBG
cord-353633-a4pu6rlu	563	55	protein	protein	NN
cord-353633-a4pu6rlu	563	56	as	as	IN
cord-353633-a4pu6rlu	563	57	a	a	DT
cord-353633-a4pu6rlu	563	58	biomarker	biomarker	NN
cord-353633-a4pu6rlu	563	59	for	for	IN
cord-353633-a4pu6rlu	563	60	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	61	fatty	fatty	JJ
cord-353633-a4pu6rlu	563	62	liver	liver	NN
cord-353633-a4pu6rlu	563	63	disease	disease	NN
cord-353633-a4pu6rlu	563	64	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	563	65	Serum	Serum	NNP
cord-353633-a4pu6rlu	563	66	progranulin	progranulin	NNP
cord-353633-a4pu6rlu	563	67	as	as	IN
cord-353633-a4pu6rlu	563	68	an	an	DT
cord-353633-a4pu6rlu	563	69	independent	independent	JJ
cord-353633-a4pu6rlu	563	70	marker	marker	NN
cord-353633-a4pu6rlu	563	71	of	of	IN
cord-353633-a4pu6rlu	563	72	liver	liver	NN
cord-353633-a4pu6rlu	563	73	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	563	74	in	in	IN
cord-353633-a4pu6rlu	563	75	patients	patient	NNS
cord-353633-a4pu6rlu	563	76	with	with	IN
cord-353633-a4pu6rlu	563	77	biopsy	biopsy	NN
cord-353633-a4pu6rlu	563	78	-	-	HYPH
cord-353633-a4pu6rlu	563	79	proven	prove	VBN
cord-353633-a4pu6rlu	563	80	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	81	fatty	fatty	JJ
cord-353633-a4pu6rlu	563	82	liver	liver	NN
cord-353633-a4pu6rlu	563	83	disease	disease	NN
cord-353633-a4pu6rlu	563	84	Identification	identification	NN
cord-353633-a4pu6rlu	563	85	of	of	IN
cord-353633-a4pu6rlu	563	86	a	a	DT
cord-353633-a4pu6rlu	563	87	support	support	NN
cord-353633-a4pu6rlu	563	88	vector	vector	NN
cord-353633-a4pu6rlu	563	89	machine	machine	NN
cord-353633-a4pu6rlu	563	90	-	-	HYPH
cord-353633-a4pu6rlu	563	91	based	base	VBN
cord-353633-a4pu6rlu	563	92	biomarker	biomarker	NN
cord-353633-a4pu6rlu	563	93	panel	panel	NN
cord-353633-a4pu6rlu	563	94	with	with	IN
cord-353633-a4pu6rlu	563	95	high	high	JJ
cord-353633-a4pu6rlu	563	96	sensitivity	sensitivity	NN
cord-353633-a4pu6rlu	563	97	and	and	CC
cord-353633-a4pu6rlu	563	98	specificity	specificity	NN
cord-353633-a4pu6rlu	563	99	for	for	IN
cord-353633-a4pu6rlu	563	100	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	101	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	563	102	Derivation	Derivation	NNP
cord-353633-a4pu6rlu	563	103	and	and	CC
cord-353633-a4pu6rlu	563	104	validation	validation	NN
cord-353633-a4pu6rlu	563	105	of	of	IN
cord-353633-a4pu6rlu	563	106	a	a	DT
cord-353633-a4pu6rlu	563	107	scoring	scoring	NN
cord-353633-a4pu6rlu	563	108	system	system	NN
cord-353633-a4pu6rlu	563	109	for	for	IN
cord-353633-a4pu6rlu	563	110	predicting	predict	VBG
cord-353633-a4pu6rlu	563	111	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	112	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	563	113	in	in	IN
cord-353633-a4pu6rlu	563	114	Taiwanese	taiwanese	JJ
cord-353633-a4pu6rlu	563	115	patients	patient	NNS
cord-353633-a4pu6rlu	563	116	with	with	IN
cord-353633-a4pu6rlu	563	117	severe	severe	JJ
cord-353633-a4pu6rlu	563	118	obesity	obesity	NN
cord-353633-a4pu6rlu	563	119	Nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	120	fatty	fatty	JJ
cord-353633-a4pu6rlu	563	121	liver	liver	NN
cord-353633-a4pu6rlu	563	122	disease	disease	NN
cord-353633-a4pu6rlu	563	123	:	:	:
cord-353633-a4pu6rlu	563	124	predictors	predictor	NNS
cord-353633-a4pu6rlu	563	125	of	of	IN
cord-353633-a4pu6rlu	563	126	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	127	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	563	128	and	and	CC
cord-353633-a4pu6rlu	563	129	liver	liver	NN
cord-353633-a4pu6rlu	563	130	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	563	131	in	in	IN
cord-353633-a4pu6rlu	563	132	the	the	DT
cord-353633-a4pu6rlu	563	133	severely	severely	RB
cord-353633-a4pu6rlu	563	134	obese	obese	JJ
cord-353633-a4pu6rlu	563	135	Noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	563	136	assessment	assessment	NN
cord-353633-a4pu6rlu	563	137	of	of	IN
cord-353633-a4pu6rlu	563	138	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	563	139	steatosis	steatosis	NN
cord-353633-a4pu6rlu	563	140	and	and	CC
cord-353633-a4pu6rlu	563	141	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	563	142	in	in	IN
cord-353633-a4pu6rlu	563	143	patients	patient	NNS
cord-353633-a4pu6rlu	563	144	with	with	IN
cord-353633-a4pu6rlu	563	145	severe	severe	JJ
cord-353633-a4pu6rlu	563	146	obesity	obesity	NN
cord-353633-a4pu6rlu	563	147	Non	non	JJ
cord-353633-a4pu6rlu	563	148	-	-	JJ
cord-353633-a4pu6rlu	563	149	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	563	150	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	563	151	:	:	:
cord-353633-a4pu6rlu	563	152	a	a	DT
cord-353633-a4pu6rlu	563	153	non	non	JJ
cord-353633-a4pu6rlu	563	154	-	-	JJ
cord-353633-a4pu6rlu	563	155	invasive	invasive	JJ
cord-353633-a4pu6rlu	563	156	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	563	157	by	by	IN
cord-353633-a4pu6rlu	563	158	analysis	analysis	NN
cord-353633-a4pu6rlu	563	159	of	of	IN
cord-353633-a4pu6rlu	563	160	exhaled	exhale	VBN
cord-353633-a4pu6rlu	563	161	breath	breath	NN
cord-353633-a4pu6rlu	563	162	How	how	WRB
cord-353633-a4pu6rlu	563	163	adiponectin	adiponectin	NN
cord-353633-a4pu6rlu	563	164	,	,	,
cord-353633-a4pu6rlu	563	165	leptin	leptin	NN
cord-353633-a4pu6rlu	563	166	,	,	,
cord-353633-a4pu6rlu	563	167	and	and	CC
cord-353633-a4pu6rlu	563	168	ghrelin	ghrelin	NN
cord-353633-a4pu6rlu	563	169	orchestrate	orchestrate	VBP
cord-353633-a4pu6rlu	563	170	together	together	RB
cord-353633-a4pu6rlu	563	171	and	and	CC
cord-353633-a4pu6rlu	563	172	correlate	correlate	VB
cord-353633-a4pu6rlu	563	173	with	with	IN
cord-353633-a4pu6rlu	563	174	the	the	DT
cord-353633-a4pu6rlu	563	175	severity	severity	NN
cord-353633-a4pu6rlu	563	176	of	of	IN
cord-353633-a4pu6rlu	563	177	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	563	178	fatty	fatty	JJ
cord-353633-a4pu6rlu	563	179	liver	liver	NN
cord-353633-a4pu6rlu	563	180	disease	disease	NN
cord-353633-a4pu6rlu	564	1	A	a	DT
cord-353633-a4pu6rlu	564	2	newly	newly	RB
cord-353633-a4pu6rlu	564	3	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	564	4	model	model	NN
cord-353633-a4pu6rlu	564	5	for	for	IN
cord-353633-a4pu6rlu	564	6	prediction	prediction	NN
cord-353633-a4pu6rlu	564	7	of	of	IN
cord-353633-a4pu6rlu	564	8	non	non	JJ
cord-353633-a4pu6rlu	564	9	-	-	JJ
cord-353633-a4pu6rlu	564	10	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	564	11	fatty	fatty	JJ
cord-353633-a4pu6rlu	564	12	liver	liver	NN
cord-353633-a4pu6rlu	564	13	disease	disease	NN
cord-353633-a4pu6rlu	564	14	:	:	:
cord-353633-a4pu6rlu	564	15	utility	utility	NN
cord-353633-a4pu6rlu	564	16	of	of	IN
cord-353633-a4pu6rlu	564	17	serum	serum	NN
cord-353633-a4pu6rlu	564	18	prolactin	prolactin	NN
cord-353633-a4pu6rlu	564	19	levels	level	NNS
cord-353633-a4pu6rlu	565	1	A	a	DT
cord-353633-a4pu6rlu	565	2	new	new	JJ
cord-353633-a4pu6rlu	565	3	composite	composite	JJ
cord-353633-a4pu6rlu	565	4	model	model	NN
cord-353633-a4pu6rlu	565	5	including	include	VBG
cord-353633-a4pu6rlu	565	6	metabolic	metabolic	JJ
cord-353633-a4pu6rlu	565	7	syndrome	syndrome	NN
cord-353633-a4pu6rlu	565	8	,	,	,
cord-353633-a4pu6rlu	565	9	alanine	alanine	NN
cord-353633-a4pu6rlu	565	10	aminotransferase	aminotransferase	NN
cord-353633-a4pu6rlu	565	11	and	and	CC
cord-353633-a4pu6rlu	565	12	cytokeratin-18	cytokeratin-18	NN
cord-353633-a4pu6rlu	565	13	for	for	IN
cord-353633-a4pu6rlu	565	14	the	the	DT
cord-353633-a4pu6rlu	565	15	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	565	16	of	of	IN
cord-353633-a4pu6rlu	565	17	non	non	JJ
cord-353633-a4pu6rlu	565	18	-	-	JJ
cord-353633-a4pu6rlu	565	19	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	565	20	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	565	21	in	in	IN
cord-353633-a4pu6rlu	565	22	morbidly	morbidly	RB
cord-353633-a4pu6rlu	565	23	obese	obese	JJ
cord-353633-a4pu6rlu	565	24	patients	patient	NNS
cord-353633-a4pu6rlu	566	1	A	a	DT
cord-353633-a4pu6rlu	566	2	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	566	3	clinical	clinical	JJ
cord-353633-a4pu6rlu	566	4	scoring	scoring	NN
cord-353633-a4pu6rlu	566	5	model	model	NN
cord-353633-a4pu6rlu	566	6	predicts	predict	VBZ
cord-353633-a4pu6rlu	566	7	risk	risk	NN
cord-353633-a4pu6rlu	566	8	of	of	IN
cord-353633-a4pu6rlu	566	9	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	566	10	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	566	11	in	in	IN
cord-353633-a4pu6rlu	566	12	morbidly	morbidly	RB
cord-353633-a4pu6rlu	566	13	obese	obese	JJ
cord-353633-a4pu6rlu	566	14	patients	patient	NNS
cord-353633-a4pu6rlu	566	15	Serum	serum	NN
cord-353633-a4pu6rlu	566	16	ferritin	ferritin	NN
cord-353633-a4pu6rlu	566	17	is	be	VBZ
cord-353633-a4pu6rlu	566	18	a	a	DT
cord-353633-a4pu6rlu	566	19	clinical	clinical	JJ
cord-353633-a4pu6rlu	566	20	biomarker	biomarker	NN
cord-353633-a4pu6rlu	566	21	in	in	IN
cord-353633-a4pu6rlu	566	22	Japanese	japanese	JJ
cord-353633-a4pu6rlu	566	23	patients	patient	NNS
cord-353633-a4pu6rlu	566	24	with	with	IN
cord-353633-a4pu6rlu	566	25	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	566	26	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	566	27	(	(	-LRB-
cord-353633-a4pu6rlu	566	28	NASH	NASH	NNP
cord-353633-a4pu6rlu	566	29	)	)	-RRB-
cord-353633-a4pu6rlu	566	30	independent	independent	NN
cord-353633-a4pu6rlu	566	31	of	of	IN
cord-353633-a4pu6rlu	566	32	HFE	HFE	NNP
cord-353633-a4pu6rlu	566	33	gene	gene	NN
cord-353633-a4pu6rlu	566	34	mutation	mutation	NN
cord-353633-a4pu6rlu	566	35	Serum	serum	NN
cord-353633-a4pu6rlu	566	36	thioredoxin	thioredoxin	NN
cord-353633-a4pu6rlu	566	37	levels	level	NNS
cord-353633-a4pu6rlu	566	38	as	as	IN
cord-353633-a4pu6rlu	566	39	a	a	DT
cord-353633-a4pu6rlu	566	40	predictor	predictor	NN
cord-353633-a4pu6rlu	566	41	of	of	IN
cord-353633-a4pu6rlu	566	42	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	566	43	in	in	IN
cord-353633-a4pu6rlu	566	44	patients	patient	NNS
cord-353633-a4pu6rlu	566	45	with	with	IN
cord-353633-a4pu6rlu	566	46	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	566	47	fatty	fatty	JJ
cord-353633-a4pu6rlu	566	48	liver	liver	NN
cord-353633-a4pu6rlu	566	49	disease	disease	NN
cord-353633-a4pu6rlu	567	1	A	a	DT
cord-353633-a4pu6rlu	567	2	simple	simple	JJ
cord-353633-a4pu6rlu	567	3	clinical	clinical	JJ
cord-353633-a4pu6rlu	567	4	scoring	scoring	NN
cord-353633-a4pu6rlu	567	5	system	system	NN
cord-353633-a4pu6rlu	567	6	using	use	VBG
cord-353633-a4pu6rlu	567	7	ferritin	ferritin	NN
cord-353633-a4pu6rlu	567	8	,	,	,
cord-353633-a4pu6rlu	567	9	fasting	fast	VBG
cord-353633-a4pu6rlu	567	10	insulin	insulin	NN
cord-353633-a4pu6rlu	567	11	,	,	,
cord-353633-a4pu6rlu	567	12	and	and	CC
cord-353633-a4pu6rlu	567	13	type	type	NN
cord-353633-a4pu6rlu	567	14	IV	IV	NNP
cord-353633-a4pu6rlu	567	15	collagen	collagen	NN
cord-353633-a4pu6rlu	567	16	7S	7S	NNP
cord-353633-a4pu6rlu	567	17	for	for	IN
cord-353633-a4pu6rlu	567	18	predicting	predict	VBG
cord-353633-a4pu6rlu	567	19	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	567	20	in	in	IN
cord-353633-a4pu6rlu	567	21	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	567	22	fatty	fatty	JJ
cord-353633-a4pu6rlu	567	23	liver	liver	NN
cord-353633-a4pu6rlu	567	24	disease	disease	NN
cord-353633-a4pu6rlu	567	25	Combined	Combined	NNP
cord-353633-a4pu6rlu	567	26	Serum	Serum	NNP
cord-353633-a4pu6rlu	567	27	Biomarkers	Biomarkers	NNPS
cord-353633-a4pu6rlu	567	28	in	in	IN
cord-353633-a4pu6rlu	567	29	Non	non	JJ
cord-353633-a4pu6rlu	567	30	-	-	JJ
cord-353633-a4pu6rlu	567	31	Invasive	invasive	JJ
cord-353633-a4pu6rlu	567	32	Diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	567	33	of	of	IN
cord-353633-a4pu6rlu	567	34	Non	non	JJ
cord-353633-a4pu6rlu	567	35	-	-	NNP
cord-353633-a4pu6rlu	567	36	Alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	567	37	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	568	1	A	a	DT
cord-353633-a4pu6rlu	568	2	4-polymorphism	4-polymorphism	CD
cord-353633-a4pu6rlu	568	3	risk	risk	NN
cord-353633-a4pu6rlu	568	4	score	score	NN
cord-353633-a4pu6rlu	568	5	predicts	predict	VBZ
cord-353633-a4pu6rlu	568	6	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	568	7	in	in	IN
cord-353633-a4pu6rlu	568	8	children	child	NNS
cord-353633-a4pu6rlu	568	9	with	with	IN
cord-353633-a4pu6rlu	568	10	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	568	11	fatty	fatty	JJ
cord-353633-a4pu6rlu	568	12	liver	liver	NN
cord-353633-a4pu6rlu	568	13	disease	disease	NN
cord-353633-a4pu6rlu	569	1	A	a	DT
cord-353633-a4pu6rlu	569	2	population	population	NN
cord-353633-a4pu6rlu	569	3	-	-	HYPH
cord-353633-a4pu6rlu	569	4	based	base	VBN
cord-353633-a4pu6rlu	569	5	study	study	NN
cord-353633-a4pu6rlu	569	6	on	on	IN
cord-353633-a4pu6rlu	569	7	the	the	DT
cord-353633-a4pu6rlu	569	8	prevalence	prevalence	NN
cord-353633-a4pu6rlu	569	9	of	of	IN
cord-353633-a4pu6rlu	569	10	NASH	NASH	NNP
cord-353633-a4pu6rlu	569	11	using	use	VBG
cord-353633-a4pu6rlu	569	12	scores	score	NNS
cord-353633-a4pu6rlu	569	13	validated	validate	VBN
cord-353633-a4pu6rlu	569	14	against	against	IN
cord-353633-a4pu6rlu	569	15	liver	liver	NN
cord-353633-a4pu6rlu	569	16	histology	histology	NN
cord-353633-a4pu6rlu	569	17	Serum	serum	NN
cord-353633-a4pu6rlu	569	18	adipokine	adipokine	NN
cord-353633-a4pu6rlu	569	19	levels	level	NNS
cord-353633-a4pu6rlu	569	20	predictive	predictive	JJ
cord-353633-a4pu6rlu	569	21	of	of	IN
cord-353633-a4pu6rlu	569	22	liver	liver	NN
cord-353633-a4pu6rlu	569	23	injury	injury	NN
cord-353633-a4pu6rlu	569	24	in	in	IN
cord-353633-a4pu6rlu	569	25	non	non	JJ
cord-353633-a4pu6rlu	569	26	-	-	JJ
cord-353633-a4pu6rlu	569	27	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	569	28	fatty	fatty	JJ
cord-353633-a4pu6rlu	569	29	liver	liver	NN
cord-353633-a4pu6rlu	569	30	disease	disease	NN
cord-353633-a4pu6rlu	570	1	Could	Could	MD
cord-353633-a4pu6rlu	570	2	inflammatory	inflammatory	JJ
cord-353633-a4pu6rlu	570	3	markers	marker	NNS
cord-353633-a4pu6rlu	570	4	help	help	VBP
cord-353633-a4pu6rlu	570	5	diagnose	diagnose	VB
cord-353633-a4pu6rlu	570	6	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	570	7	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	570	8	?	?	.
cord-353633-a4pu6rlu	571	1	Retinol	retinol	NN
cord-353633-a4pu6rlu	571	2	-	-	HYPH
cord-353633-a4pu6rlu	571	3	binding	bind	VBG
cord-353633-a4pu6rlu	571	4	protein	protein	NN
cord-353633-a4pu6rlu	571	5	4	4	CD
cord-353633-a4pu6rlu	571	6	:	:	:
cord-353633-a4pu6rlu	571	7	a	a	DT
cord-353633-a4pu6rlu	571	8	promising	promising	JJ
cord-353633-a4pu6rlu	571	9	circulating	circulate	VBG
cord-353633-a4pu6rlu	571	10	marker	marker	NN
cord-353633-a4pu6rlu	571	11	of	of	IN
cord-353633-a4pu6rlu	571	12	liver	liver	NN
cord-353633-a4pu6rlu	571	13	damage	damage	NN
cord-353633-a4pu6rlu	571	14	in	in	IN
cord-353633-a4pu6rlu	571	15	pediatric	pediatric	JJ
cord-353633-a4pu6rlu	571	16	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	571	17	fatty	fatty	JJ
cord-353633-a4pu6rlu	571	18	liver	liver	NN
cord-353633-a4pu6rlu	571	19	disease	disease	NN
cord-353633-a4pu6rlu	571	20	Serum	serum	NN
cord-353633-a4pu6rlu	571	21	levels	level	NNS
cord-353633-a4pu6rlu	571	22	of	of	IN
cord-353633-a4pu6rlu	571	23	hyaluronic	hyaluronic	NN
cord-353633-a4pu6rlu	571	24	acid	acid	NN
cord-353633-a4pu6rlu	571	25	and	and	CC
cord-353633-a4pu6rlu	571	26	tissue	tissue	NN
cord-353633-a4pu6rlu	571	27	metalloproteinase	metalloproteinase	NN
cord-353633-a4pu6rlu	571	28	inhibitor-1	inhibitor-1	NNP
cord-353633-a4pu6rlu	572	1	combined	combine	VBN
cord-353633-a4pu6rlu	572	2	with	with	IN
cord-353633-a4pu6rlu	572	3	age	age	NN
cord-353633-a4pu6rlu	572	4	predict	predict	VBP
cord-353633-a4pu6rlu	572	5	the	the	DT
cord-353633-a4pu6rlu	572	6	presence	presence	NN
cord-353633-a4pu6rlu	572	7	of	of	IN
cord-353633-a4pu6rlu	572	8	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	572	9	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	572	10	in	in	IN
cord-353633-a4pu6rlu	572	11	a	a	DT
cord-353633-a4pu6rlu	572	12	pilot	pilot	JJ
cord-353633-a4pu6rlu	572	13	cohort	cohort	NN
cord-353633-a4pu6rlu	572	14	of	of	IN
cord-353633-a4pu6rlu	572	15	subjects	subject	NNS
cord-353633-a4pu6rlu	572	16	with	with	IN
cord-353633-a4pu6rlu	572	17	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	572	18	fatty	fatty	JJ
cord-353633-a4pu6rlu	572	19	liver	liver	NN
cord-353633-a4pu6rlu	572	20	disease	disease	NN
cord-353633-a4pu6rlu	573	1	A	a	DT
cord-353633-a4pu6rlu	573	2	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	573	3	model	model	NN
cord-353633-a4pu6rlu	573	4	to	to	TO
cord-353633-a4pu6rlu	573	5	differentiate	differentiate	VB
cord-353633-a4pu6rlu	573	6	simple	simple	JJ
cord-353633-a4pu6rlu	573	7	steatosis	steatosis	NN
cord-353633-a4pu6rlu	573	8	from	from	IN
cord-353633-a4pu6rlu	573	9	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	573	10	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	573	11	based	base	VBN
cord-353633-a4pu6rlu	573	12	on	on	IN
cord-353633-a4pu6rlu	573	13	the	the	DT
cord-353633-a4pu6rlu	573	14	likelihood	likelihood	NN
cord-353633-a4pu6rlu	573	15	ratio	ratio	NN
cord-353633-a4pu6rlu	573	16	form	form	NN
cord-353633-a4pu6rlu	573	17	of	of	IN
cord-353633-a4pu6rlu	573	18	Bayes	Bayes	NNP
cord-353633-a4pu6rlu	573	19	theorem	theorem	NN
cord-353633-a4pu6rlu	573	20	A	a	DT
cord-353633-a4pu6rlu	573	21	novel	novel	JJ
cord-353633-a4pu6rlu	573	22	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	573	23	biomarker	biomarker	NN
cord-353633-a4pu6rlu	573	24	panel	panel	NN
cord-353633-a4pu6rlu	573	25	for	for	IN
cord-353633-a4pu6rlu	573	26	obesity	obesity	NN
cord-353633-a4pu6rlu	573	27	-	-	HYPH
cord-353633-a4pu6rlu	573	28	related	relate	VBN
cord-353633-a4pu6rlu	573	29	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	573	30	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	573	31	(	(	-LRB-
cord-353633-a4pu6rlu	573	32	NASH	NASH	NNP
cord-353633-a4pu6rlu	573	33	)	)	-RRB-
cord-353633-a4pu6rlu	574	1	Usefulness	usefulness	NN
cord-353633-a4pu6rlu	574	2	of	of	IN
cord-353633-a4pu6rlu	574	3	a	a	DT
cord-353633-a4pu6rlu	574	4	combined	combined	JJ
cord-353633-a4pu6rlu	574	5	evaluation	evaluation	NN
cord-353633-a4pu6rlu	574	6	of	of	IN
cord-353633-a4pu6rlu	574	7	the	the	DT
cord-353633-a4pu6rlu	574	8	serum	serum	NN
cord-353633-a4pu6rlu	574	9	adiponectin	adiponectin	NN
cord-353633-a4pu6rlu	574	10	level	level	NN
cord-353633-a4pu6rlu	574	11	,	,	,
cord-353633-a4pu6rlu	574	12	HOMA	HOMA	NNP
cord-353633-a4pu6rlu	574	13	-	-	HYPH
cord-353633-a4pu6rlu	574	14	IR	IR	NNP
cord-353633-a4pu6rlu	574	15	,	,	,
cord-353633-a4pu6rlu	574	16	and	and	CC
cord-353633-a4pu6rlu	574	17	serum	serum	NN
cord-353633-a4pu6rlu	574	18	type	type	NN
cord-353633-a4pu6rlu	574	19	IV	IV	NNP
cord-353633-a4pu6rlu	574	20	collagen	collagen	NN
cord-353633-a4pu6rlu	574	21	7S	7s	JJ
cord-353633-a4pu6rlu	574	22	level	level	NN
cord-353633-a4pu6rlu	574	23	to	to	TO
cord-353633-a4pu6rlu	574	24	predict	predict	VB
cord-353633-a4pu6rlu	574	25	the	the	DT
cord-353633-a4pu6rlu	574	26	early	early	JJ
cord-353633-a4pu6rlu	574	27	stage	stage	NN
cord-353633-a4pu6rlu	574	28	of	of	IN
cord-353633-a4pu6rlu	574	29	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	574	30	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	574	31	Accuracy	Accuracy	NNP
cord-353633-a4pu6rlu	574	32	of	of	IN
cord-353633-a4pu6rlu	574	33	proton	proton	NN
cord-353633-a4pu6rlu	574	34	magnetic	magnetic	JJ
cord-353633-a4pu6rlu	574	35	resonance	resonance	NN
cord-353633-a4pu6rlu	574	36	for	for	IN
cord-353633-a4pu6rlu	574	37	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	574	38	non	non	JJ
cord-353633-a4pu6rlu	574	39	-	-	JJ
cord-353633-a4pu6rlu	574	40	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	574	41	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	575	1	:	:	:
cord-353633-a4pu6rlu	575	2	a	a	DT
cord-353633-a4pu6rlu	575	3	meta	meta	JJ
cord-353633-a4pu6rlu	575	4	-	-	HYPH
cord-353633-a4pu6rlu	575	5	analysis	analysis	NN
cord-353633-a4pu6rlu	575	6	Plasma	Plasma	NNP
cord-353633-a4pu6rlu	575	7	Pentraxin3	Pentraxin3	NNP
cord-353633-a4pu6rlu	575	8	is	be	VBZ
cord-353633-a4pu6rlu	575	9	a	a	DT
cord-353633-a4pu6rlu	575	10	novel	novel	JJ
cord-353633-a4pu6rlu	575	11	marker	marker	NN
cord-353633-a4pu6rlu	575	12	for	for	IN
cord-353633-a4pu6rlu	575	13	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	575	14	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	575	15	(	(	-LRB-
cord-353633-a4pu6rlu	575	16	NASH	NASH	NNP
cord-353633-a4pu6rlu	575	17	)	)	-RRB-
cord-353633-a4pu6rlu	575	18	Validation	validation	NN
cord-353633-a4pu6rlu	575	19	of	of	IN
cord-353633-a4pu6rlu	575	20	terminal	terminal	JJ
cord-353633-a4pu6rlu	575	21	peptide	peptide	NN
cord-353633-a4pu6rlu	575	22	of	of	IN
cord-353633-a4pu6rlu	575	23	procollagen	procollagen	NNP
cord-353633-a4pu6rlu	575	24	III	III	NNP
cord-353633-a4pu6rlu	575	25	for	for	IN
cord-353633-a4pu6rlu	575	26	the	the	DT
cord-353633-a4pu6rlu	575	27	detection	detection	NN
cord-353633-a4pu6rlu	575	28	and	and	CC
cord-353633-a4pu6rlu	575	29	assessment	assessment	NN
cord-353633-a4pu6rlu	575	30	of	of	IN
cord-353633-a4pu6rlu	575	31	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	575	32	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	575	33	in	in	IN
cord-353633-a4pu6rlu	575	34	patients	patient	NNS
cord-353633-a4pu6rlu	575	35	with	with	IN
cord-353633-a4pu6rlu	575	36	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	575	37	fatty	fatty	JJ
cord-353633-a4pu6rlu	575	38	liver	liver	NN
cord-353633-a4pu6rlu	575	39	disease	disease	NN
cord-353633-a4pu6rlu	575	40	Diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	575	41	value	value	NN
cord-353633-a4pu6rlu	575	42	of	of	IN
cord-353633-a4pu6rlu	575	43	serum	serum	NN
cord-353633-a4pu6rlu	575	44	prolidase	prolidase	NN
cord-353633-a4pu6rlu	575	45	enzyme	enzyme	NN
cord-353633-a4pu6rlu	575	46	activity	activity	NN
cord-353633-a4pu6rlu	575	47	to	to	TO
cord-353633-a4pu6rlu	575	48	predict	predict	VB
cord-353633-a4pu6rlu	575	49	the	the	DT
cord-353633-a4pu6rlu	575	50	liver	liver	NN
cord-353633-a4pu6rlu	575	51	histological	histological	JJ
cord-353633-a4pu6rlu	575	52	lesions	lesion	NNS
cord-353633-a4pu6rlu	575	53	in	in	IN
cord-353633-a4pu6rlu	575	54	non	non	JJ
cord-353633-a4pu6rlu	575	55	-	-	JJ
cord-353633-a4pu6rlu	575	56	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	575	57	fatty	fatty	JJ
cord-353633-a4pu6rlu	575	58	liver	liver	NN
cord-353633-a4pu6rlu	575	59	disease	disease	NN
cord-353633-a4pu6rlu	575	60	:	:	:
cord-353633-a4pu6rlu	575	61	a	a	DT
cord-353633-a4pu6rlu	575	62	surrogate	surrogate	JJ
cord-353633-a4pu6rlu	575	63	marker	marker	NN
cord-353633-a4pu6rlu	575	64	to	to	TO
cord-353633-a4pu6rlu	575	65	distinguish	distinguish	VB
cord-353633-a4pu6rlu	575	66	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	575	67	from	from	IN
cord-353633-a4pu6rlu	575	68	simple	simple	JJ
cord-353633-a4pu6rlu	575	69	steatosis	steatosis	NN
cord-353633-a4pu6rlu	575	70	Prediction	prediction	NN
cord-353633-a4pu6rlu	575	71	of	of	IN
cord-353633-a4pu6rlu	575	72	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	575	73	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	575	74	Liver	Liver	NNP
cord-353633-a4pu6rlu	575	75	Disease	Disease	NNP
cord-353633-a4pu6rlu	575	76	Via	Via	NNP
cord-353633-a4pu6rlu	575	77	a	a	DT
cord-353633-a4pu6rlu	575	78	Novel	Novel	NNP
cord-353633-a4pu6rlu	575	79	Panel	Panel	NNP
cord-353633-a4pu6rlu	575	80	of	of	IN
cord-353633-a4pu6rlu	575	81	Serum	Serum	NNP
cord-353633-a4pu6rlu	575	82	Adipokines	Adipokines	NNPS
cord-353633-a4pu6rlu	575	83	Predictive	Predictive	NNP
cord-353633-a4pu6rlu	575	84	factors	factor	NNS
cord-353633-a4pu6rlu	575	85	for	for	IN
cord-353633-a4pu6rlu	575	86	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	575	87	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	575	88	(	(	-LRB-
cord-353633-a4pu6rlu	575	89	NASH	NASH	NNP
cord-353633-a4pu6rlu	575	90	)	)	-RRB-
cord-353633-a4pu6rlu	575	91	in	in	IN
cord-353633-a4pu6rlu	575	92	patients	patient	NNS
cord-353633-a4pu6rlu	575	93	with	with	IN
cord-353633-a4pu6rlu	575	94	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	575	95	fatty	fatty	JJ
cord-353633-a4pu6rlu	575	96	liver	liver	NN
cord-353633-a4pu6rlu	575	97	disease	disease	NN
cord-353633-a4pu6rlu	575	98	(	(	-LRB-
cord-353633-a4pu6rlu	575	99	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	575	100	)	)	-RRB-
cord-353633-a4pu6rlu	575	101	MACK-3	mack-3	NN
cord-353633-a4pu6rlu	575	102	(	(	-LRB-
cord-353633-a4pu6rlu	575	103	combination	combination	NN
cord-353633-a4pu6rlu	575	104	of	of	IN
cord-353633-a4pu6rlu	575	105	hoMa	hoMa	NNP
cord-353633-a4pu6rlu	575	106	,	,	,
cord-353633-a4pu6rlu	575	107	Ast	Ast	NNP
cord-353633-a4pu6rlu	575	108	and	and	CC
cord-353633-a4pu6rlu	575	109	CK18	CK18	NNP
cord-353633-a4pu6rlu	575	110	)	)	-RRB-
cord-353633-a4pu6rlu	575	111	:	:	:
cord-353633-a4pu6rlu	576	1	A	a	DT
cord-353633-a4pu6rlu	576	2	promising	promising	JJ
cord-353633-a4pu6rlu	576	3	novel	novel	NN
cord-353633-a4pu6rlu	576	4	biomarker	biomarker	NN
cord-353633-a4pu6rlu	576	5	for	for	IN
cord-353633-a4pu6rlu	576	6	fibrotic	fibrotic	JJ
cord-353633-a4pu6rlu	576	7	non	non	JJ
cord-353633-a4pu6rlu	576	8	-	-	JJ
cord-353633-a4pu6rlu	576	9	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	576	10	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	576	11	Noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	576	12	assessment	assessment	NN
cord-353633-a4pu6rlu	576	13	of	of	IN
cord-353633-a4pu6rlu	576	14	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	576	15	as	as	IN
cord-353633-a4pu6rlu	576	16	systemic	systemic	JJ
cord-353633-a4pu6rlu	576	17	disease	disease	NN
cord-353633-a4pu6rlu	576	18	-	-	:
cord-353633-a4pu6rlu	576	19	A	a	DT
cord-353633-a4pu6rlu	576	20	machine	machine	NN
cord-353633-a4pu6rlu	576	21	learning	learning	NN
cord-353633-a4pu6rlu	576	22	perspective	perspective	NN
cord-353633-a4pu6rlu	576	23	Non	non	JJ
cord-353633-a4pu6rlu	576	24	-	-	JJ
cord-353633-a4pu6rlu	576	25	invasive	invasive	JJ
cord-353633-a4pu6rlu	576	26	diagnosis	diagnosis	NN
cord-353633-a4pu6rlu	576	27	of	of	IN
cord-353633-a4pu6rlu	576	28	non	non	JJ
cord-353633-a4pu6rlu	576	29	-	-	JJ
cord-353633-a4pu6rlu	576	30	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	576	31	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	576	32	by	by	IN
cord-353633-a4pu6rlu	576	33	combined	combined	JJ
cord-353633-a4pu6rlu	576	34	serum	serum	NN
cord-353633-a4pu6rlu	576	35	biomarkers	biomarker	NNS
cord-353633-a4pu6rlu	576	36	Meta	Meta	NNP
cord-353633-a4pu6rlu	576	37	-	-	HYPH
cord-353633-a4pu6rlu	576	38	analysis	analysis	NN
cord-353633-a4pu6rlu	576	39	:	:	:
cord-353633-a4pu6rlu	577	1	natural	natural	JJ
cord-353633-a4pu6rlu	577	2	history	history	NN
cord-353633-a4pu6rlu	577	3	of	of	IN
cord-353633-a4pu6rlu	577	4	non	non	JJ
cord-353633-a4pu6rlu	577	5	-	-	JJ
cord-353633-a4pu6rlu	577	6	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	577	7	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	8	liver	liver	NN
cord-353633-a4pu6rlu	577	9	disease	disease	NN
cord-353633-a4pu6rlu	577	10	(	(	-LRB-
cord-353633-a4pu6rlu	577	11	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	577	12	)	)	-RRB-
cord-353633-a4pu6rlu	577	13	and	and	CC
cord-353633-a4pu6rlu	577	14	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	577	15	accuracy	accuracy	NN
cord-353633-a4pu6rlu	577	16	of	of	IN
cord-353633-a4pu6rlu	577	17	non	non	JJ
cord-353633-a4pu6rlu	577	18	-	-	JJ
cord-353633-a4pu6rlu	577	19	invasive	invasive	JJ
cord-353633-a4pu6rlu	577	20	tests	test	NNS
cord-353633-a4pu6rlu	577	21	for	for	IN
cord-353633-a4pu6rlu	577	22	liver	liver	NN
cord-353633-a4pu6rlu	577	23	disease	disease	NN
cord-353633-a4pu6rlu	577	24	severity	severity	NN
cord-353633-a4pu6rlu	577	25	Soluble	soluble	JJ
cord-353633-a4pu6rlu	577	26	forms	form	NNS
cord-353633-a4pu6rlu	577	27	of	of	IN
cord-353633-a4pu6rlu	577	28	extracellular	extracellular	JJ
cord-353633-a4pu6rlu	577	29	cytokeratin	cytokeratin	NNP
cord-353633-a4pu6rlu	577	30	18	18	CD
cord-353633-a4pu6rlu	577	31	may	may	MD
cord-353633-a4pu6rlu	577	32	differentiate	differentiate	VB
cord-353633-a4pu6rlu	577	33	simple	simple	JJ
cord-353633-a4pu6rlu	577	34	steatosis	steatosis	NN
cord-353633-a4pu6rlu	577	35	from	from	IN
cord-353633-a4pu6rlu	577	36	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	37	steatohepatitis	steatohepatitis	NNP
cord-353633-a4pu6rlu	577	38	Clinical	clinical	JJ
cord-353633-a4pu6rlu	577	39	model	model	NN
cord-353633-a4pu6rlu	577	40	for	for	IN
cord-353633-a4pu6rlu	577	41	distinguishing	distinguish	VBG
cord-353633-a4pu6rlu	577	42	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	43	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	577	44	from	from	IN
cord-353633-a4pu6rlu	577	45	simple	simple	JJ
cord-353633-a4pu6rlu	577	46	steatosis	steatosis	NN
cord-353633-a4pu6rlu	577	47	in	in	IN
cord-353633-a4pu6rlu	577	48	patients	patient	NNS
cord-353633-a4pu6rlu	577	49	with	with	IN
cord-353633-a4pu6rlu	577	50	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	51	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	52	liver	liver	NN
cord-353633-a4pu6rlu	577	53	disease	disease	NN
cord-353633-a4pu6rlu	577	54	Development	Development	NNP
cord-353633-a4pu6rlu	577	55	and	and	CC
cord-353633-a4pu6rlu	577	56	validation	validation	NN
cord-353633-a4pu6rlu	577	57	of	of	IN
cord-353633-a4pu6rlu	577	58	a	a	DT
cord-353633-a4pu6rlu	577	59	novel	novel	JJ
cord-353633-a4pu6rlu	577	60	non	non	JJ
cord-353633-a4pu6rlu	577	61	-	-	JJ
cord-353633-a4pu6rlu	577	62	invasive	invasive	JJ
cord-353633-a4pu6rlu	577	63	test	test	NN
cord-353633-a4pu6rlu	577	64	for	for	IN
cord-353633-a4pu6rlu	577	65	diagnosing	diagnose	VBG
cord-353633-a4pu6rlu	577	66	fibrotic	fibrotic	JJ
cord-353633-a4pu6rlu	577	67	non	non	JJ
cord-353633-a4pu6rlu	577	68	-	-	JJ
cord-353633-a4pu6rlu	577	69	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	577	70	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	577	71	in	in	IN
cord-353633-a4pu6rlu	577	72	patients	patient	NNS
cord-353633-a4pu6rlu	577	73	with	with	IN
cord-353633-a4pu6rlu	577	74	biopsy	biopsy	NN
cord-353633-a4pu6rlu	577	75	-	-	HYPH
cord-353633-a4pu6rlu	577	76	proven	prove	VBN
cord-353633-a4pu6rlu	577	77	non	non	JJ
cord-353633-a4pu6rlu	577	78	-	-	JJ
cord-353633-a4pu6rlu	577	79	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	577	80	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	81	liver	liver	NN
cord-353633-a4pu6rlu	577	82	disease	disease	NN
cord-353633-a4pu6rlu	577	83	Clinical	clinical	JJ
cord-353633-a4pu6rlu	577	84	usefulness	usefulness	NN
cord-353633-a4pu6rlu	577	85	of	of	IN
cord-353633-a4pu6rlu	577	86	biochemical	biochemical	JJ
cord-353633-a4pu6rlu	577	87	markers	marker	NNS
cord-353633-a4pu6rlu	577	88	of	of	IN
cord-353633-a4pu6rlu	577	89	liver	liver	NN
cord-353633-a4pu6rlu	577	90	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	91	in	in	IN
cord-353633-a4pu6rlu	577	92	patients	patient	NNS
cord-353633-a4pu6rlu	577	93	with	with	IN
cord-353633-a4pu6rlu	577	94	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	95	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	96	liver	liver	NN
cord-353633-a4pu6rlu	577	97	disease	disease	NN
cord-353633-a4pu6rlu	577	98	Diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	577	99	performance	performance	NN
cord-353633-a4pu6rlu	577	100	of	of	IN
cord-353633-a4pu6rlu	577	101	FibroTest	FibroTest	NNP
cord-353633-a4pu6rlu	577	102	,	,	,
cord-353633-a4pu6rlu	577	103	SteatoTest	SteatoTest	NNP
cord-353633-a4pu6rlu	577	104	and	and	CC
cord-353633-a4pu6rlu	577	105	ActiTest	ActiTest	NNP
cord-353633-a4pu6rlu	577	106	in	in	IN
cord-353633-a4pu6rlu	577	107	patients	patient	NNS
cord-353633-a4pu6rlu	577	108	with	with	IN
cord-353633-a4pu6rlu	577	109	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	577	110	using	use	VBG
cord-353633-a4pu6rlu	577	111	the	the	DT
cord-353633-a4pu6rlu	577	112	SAF	SAF	NNP
cord-353633-a4pu6rlu	577	113	score	score	NN
cord-353633-a4pu6rlu	577	114	as	as	IN
cord-353633-a4pu6rlu	577	115	histological	histological	JJ
cord-353633-a4pu6rlu	577	116	reference	reference	NN
cord-353633-a4pu6rlu	577	117	Hyaluronic	hyaluronic	NN
cord-353633-a4pu6rlu	577	118	acid	acid	NN
cord-353633-a4pu6rlu	577	119	levels	level	NNS
cord-353633-a4pu6rlu	577	120	can	can	MD
cord-353633-a4pu6rlu	577	121	predict	predict	VB
cord-353633-a4pu6rlu	577	122	severe	severe	JJ
cord-353633-a4pu6rlu	577	123	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	124	and	and	CC
cord-353633-a4pu6rlu	577	125	platelet	platelet	NN
cord-353633-a4pu6rlu	577	126	counts	count	NNS
cord-353633-a4pu6rlu	577	127	can	can	MD
cord-353633-a4pu6rlu	577	128	predict	predict	VB
cord-353633-a4pu6rlu	577	129	cirrhosis	cirrhosis	NN
cord-353633-a4pu6rlu	577	130	in	in	IN
cord-353633-a4pu6rlu	577	131	patients	patient	NNS
cord-353633-a4pu6rlu	577	132	with	with	IN
cord-353633-a4pu6rlu	577	133	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	134	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	135	liver	liver	NN
cord-353633-a4pu6rlu	577	136	disease	disease	NN
cord-353633-a4pu6rlu	577	137	Serum	serum	NN
cord-353633-a4pu6rlu	577	138	markers	marker	NNS
cord-353633-a4pu6rlu	577	139	detect	detect	VBP
cord-353633-a4pu6rlu	577	140	the	the	DT
cord-353633-a4pu6rlu	577	141	presence	presence	NN
cord-353633-a4pu6rlu	577	142	of	of	IN
cord-353633-a4pu6rlu	577	143	liver	liver	NN
cord-353633-a4pu6rlu	577	144	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	145	:	:	:
cord-353633-a4pu6rlu	577	146	a	a	DT
cord-353633-a4pu6rlu	577	147	cohort	cohort	NN
cord-353633-a4pu6rlu	577	148	study	study	NN
cord-353633-a4pu6rlu	577	149	Performance	performance	NN
cord-353633-a4pu6rlu	577	150	of	of	IN
cord-353633-a4pu6rlu	577	151	the	the	DT
cord-353633-a4pu6rlu	577	152	PRO	pro	JJ
cord-353633-a4pu6rlu	577	153	-	-	JJ
cord-353633-a4pu6rlu	577	154	C3	c3	JJ
cord-353633-a4pu6rlu	577	155	collagen	collagen	NN
cord-353633-a4pu6rlu	577	156	neo	neo	NNP
cord-353633-a4pu6rlu	577	157	-	-	HYPH
cord-353633-a4pu6rlu	577	158	epitope	epitope	JJ
cord-353633-a4pu6rlu	577	159	biomarker	biomarker	NN
cord-353633-a4pu6rlu	577	160	in	in	IN
cord-353633-a4pu6rlu	577	161	non	non	JJ
cord-353633-a4pu6rlu	577	162	-	-	JJ
cord-353633-a4pu6rlu	577	163	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	577	164	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	165	liver	liver	NN
cord-353633-a4pu6rlu	577	166	disease	disease	NN
cord-353633-a4pu6rlu	577	167	Direct	direct	JJ
cord-353633-a4pu6rlu	577	168	comparison	comparison	NN
cord-353633-a4pu6rlu	577	169	of	of	IN
cord-353633-a4pu6rlu	577	170	the	the	DT
cord-353633-a4pu6rlu	577	171	specialised	specialised	JJ
cord-353633-a4pu6rlu	577	172	blood	blood	NN
cord-353633-a4pu6rlu	577	173	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	174	tests	test	NNS
cord-353633-a4pu6rlu	577	175	FibroMeter(V2	FibroMeter(V2	NNP
cord-353633-a4pu6rlu	577	176	G	G	NNP
cord-353633-a4pu6rlu	577	177	)	)	-RRB-
cord-353633-a4pu6rlu	577	178	and	and	CC
cord-353633-a4pu6rlu	577	179	Enhanced	Enhanced	NNP
cord-353633-a4pu6rlu	577	180	Liver	Liver	NNP
cord-353633-a4pu6rlu	577	181	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	577	182	score	score	NN
cord-353633-a4pu6rlu	577	183	in	in	IN
cord-353633-a4pu6rlu	577	184	patients	patient	NNS
cord-353633-a4pu6rlu	577	185	with	with	IN
cord-353633-a4pu6rlu	577	186	non	non	JJ
cord-353633-a4pu6rlu	577	187	-	-	JJ
cord-353633-a4pu6rlu	577	188	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	577	189	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	190	liver	liver	NN
cord-353633-a4pu6rlu	577	191	disease	disease	NN
cord-353633-a4pu6rlu	577	192	from	from	IN
cord-353633-a4pu6rlu	577	193	tertiary	tertiary	JJ
cord-353633-a4pu6rlu	577	194	care	care	NN
cord-353633-a4pu6rlu	577	195	centres	centre	NNS
cord-353633-a4pu6rlu	577	196	Step	step	VB
cord-353633-a4pu6rlu	577	197	layered	layered	JJ
cord-353633-a4pu6rlu	577	198	combination	combination	NN
cord-353633-a4pu6rlu	577	199	of	of	IN
cord-353633-a4pu6rlu	577	200	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	577	201	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	202	models	model	NNS
cord-353633-a4pu6rlu	577	203	improves	improve	VBZ
cord-353633-a4pu6rlu	577	204	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	577	205	accuracy	accuracy	NN
cord-353633-a4pu6rlu	577	206	of	of	IN
cord-353633-a4pu6rlu	577	207	advanced	advanced	JJ
cord-353633-a4pu6rlu	577	208	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	209	in	in	IN
cord-353633-a4pu6rlu	577	210	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	211	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	212	liver	liver	NN
cord-353633-a4pu6rlu	577	213	disease	disease	NN
cord-353633-a4pu6rlu	577	214	Development	Development	NNP
cord-353633-a4pu6rlu	577	215	and	and	CC
cord-353633-a4pu6rlu	577	216	Validation	Validation	NNP
cord-353633-a4pu6rlu	577	217	of	of	IN
cord-353633-a4pu6rlu	577	218	Hepamet	Hepamet	NNP
cord-353633-a4pu6rlu	577	219	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	577	220	Scoring	Scoring	NNP
cord-353633-a4pu6rlu	577	221	System	System	NNP
cord-353633-a4pu6rlu	577	222	-	-	:
cord-353633-a4pu6rlu	577	223	A	A	NNP
cord-353633-a4pu6rlu	577	224	Simple	Simple	NNP
cord-353633-a4pu6rlu	577	225	,	,	,
cord-353633-a4pu6rlu	577	226	Noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	577	227	Test	test	NN
cord-353633-a4pu6rlu	577	228	to	to	TO
cord-353633-a4pu6rlu	577	229	Identify	identify	VB
cord-353633-a4pu6rlu	577	230	Patients	patient	NNS
cord-353633-a4pu6rlu	577	231	With	with	IN
cord-353633-a4pu6rlu	577	232	Nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	233	Fatty	fatty	JJ
cord-353633-a4pu6rlu	577	234	Liver	liver	NN
cord-353633-a4pu6rlu	577	235	Disease	Disease	NNP
cord-353633-a4pu6rlu	577	236	With	with	IN
cord-353633-a4pu6rlu	577	237	Advanced	Advanced	NNP
cord-353633-a4pu6rlu	577	238	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	577	239	Low	Low	NNP
cord-353633-a4pu6rlu	577	240	circulating	circulate	VBG
cord-353633-a4pu6rlu	577	241	levels	level	NNS
cord-353633-a4pu6rlu	577	242	of	of	IN
cord-353633-a4pu6rlu	577	243	dehydroepiandrosterone	dehydroepiandrosterone	NN
cord-353633-a4pu6rlu	577	244	in	in	IN
cord-353633-a4pu6rlu	577	245	histologically	histologically	RB
cord-353633-a4pu6rlu	577	246	advanced	advanced	JJ
cord-353633-a4pu6rlu	577	247	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	577	248	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	249	liver	liver	NN
cord-353633-a4pu6rlu	577	250	disease	disease	NN
cord-353633-a4pu6rlu	577	251	Validation	validation	NN
cord-353633-a4pu6rlu	577	252	of	of	IN
cord-353633-a4pu6rlu	577	253	Serum	Serum	NNP
cord-353633-a4pu6rlu	577	254	Test	Test	NNP
cord-353633-a4pu6rlu	577	255	for	for	IN
cord-353633-a4pu6rlu	577	256	Advanced	Advanced	NNP
cord-353633-a4pu6rlu	577	257	Liver	Liver	NNP
cord-353633-a4pu6rlu	577	258	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	577	259	in	in	IN
cord-353633-a4pu6rlu	577	260	Patients	Patients	NNP
cord-353633-a4pu6rlu	577	261	With	with	IN
cord-353633-a4pu6rlu	577	262	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	577	263	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	577	264	Comparison	Comparison	NNP
cord-353633-a4pu6rlu	577	265	of	of	IN
cord-353633-a4pu6rlu	577	266	FIB-4	FIB-4	NNP
cord-353633-a4pu6rlu	577	267	index	index	NN
cord-353633-a4pu6rlu	577	268	,	,	,
cord-353633-a4pu6rlu	577	269	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	577	270	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	271	score	score	NN
cord-353633-a4pu6rlu	577	272	and	and	CC
cord-353633-a4pu6rlu	577	273	BARD	BARD	NNP
cord-353633-a4pu6rlu	577	274	score	score	NN
cord-353633-a4pu6rlu	577	275	for	for	IN
cord-353633-a4pu6rlu	577	276	prediction	prediction	NN
cord-353633-a4pu6rlu	577	277	of	of	IN
cord-353633-a4pu6rlu	577	278	advanced	advanced	JJ
cord-353633-a4pu6rlu	577	279	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	577	280	in	in	IN
cord-353633-a4pu6rlu	577	281	adult	adult	NN
cord-353633-a4pu6rlu	577	282	patients	patient	NNS
cord-353633-a4pu6rlu	577	283	with	with	IN
cord-353633-a4pu6rlu	577	284	non	non	JJ
cord-353633-a4pu6rlu	577	285	-	-	JJ
cord-353633-a4pu6rlu	577	286	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	577	287	fatty	fatty	JJ
cord-353633-a4pu6rlu	577	288	liver	liver	NN
cord-353633-a4pu6rlu	577	289	disease	disease	NN
cord-353633-a4pu6rlu	577	290	:	:	:
cord-353633-a4pu6rlu	578	1	A	a	DT
cord-353633-a4pu6rlu	578	2	meta	meta	JJ
cord-353633-a4pu6rlu	578	3	-	-	HYPH
cord-353633-a4pu6rlu	578	4	analysis	analysis	NN
cord-353633-a4pu6rlu	578	5	study	study	NN
cord-353633-a4pu6rlu	578	6	NIKEI	NIKEI	NNP
cord-353633-a4pu6rlu	578	7	:	:	:
cord-353633-a4pu6rlu	578	8	a	a	DT
cord-353633-a4pu6rlu	578	9	new	new	JJ
cord-353633-a4pu6rlu	578	10	inexpensive	inexpensive	JJ
cord-353633-a4pu6rlu	578	11	and	and	CC
cord-353633-a4pu6rlu	578	12	non	non	JJ
cord-353633-a4pu6rlu	578	13	-	-	JJ
cord-353633-a4pu6rlu	578	14	invasive	invasive	JJ
cord-353633-a4pu6rlu	578	15	scoring	scoring	NN
cord-353633-a4pu6rlu	578	16	system	system	NN
cord-353633-a4pu6rlu	578	17	to	to	TO
cord-353633-a4pu6rlu	578	18	exclude	exclude	VB
cord-353633-a4pu6rlu	578	19	advanced	advanced	JJ
cord-353633-a4pu6rlu	578	20	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	578	21	in	in	IN
cord-353633-a4pu6rlu	578	22	patients	patient	NNS
cord-353633-a4pu6rlu	578	23	with	with	IN
cord-353633-a4pu6rlu	578	24	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	579	1	The	the	DT
cord-353633-a4pu6rlu	579	2	development	development	NN
cord-353633-a4pu6rlu	579	3	of	of	IN
cord-353633-a4pu6rlu	579	4	the	the	DT
cord-353633-a4pu6rlu	579	5	pediatric	pediatric	JJ
cord-353633-a4pu6rlu	579	6	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	579	7	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	579	8	score	score	NN
cord-353633-a4pu6rlu	579	9	(	(	-LRB-
cord-353633-a4pu6rlu	579	10	PNFS	PNFS	NNP
cord-353633-a4pu6rlu	579	11	)	)	-RRB-
cord-353633-a4pu6rlu	580	1	to	to	TO
cord-353633-a4pu6rlu	580	2	predict	predict	VB
cord-353633-a4pu6rlu	580	3	the	the	DT
cord-353633-a4pu6rlu	580	4	presence	presence	NN
cord-353633-a4pu6rlu	580	5	of	of	IN
cord-353633-a4pu6rlu	580	6	advanced	advanced	JJ
cord-353633-a4pu6rlu	580	7	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	580	8	in	in	IN
cord-353633-a4pu6rlu	580	9	children	child	NNS
cord-353633-a4pu6rlu	580	10	with	with	IN
cord-353633-a4pu6rlu	580	11	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	580	12	fatty	fatty	JJ
cord-353633-a4pu6rlu	580	13	liver	liver	NN
cord-353633-a4pu6rlu	580	14	disease	disease	NN
cord-353633-a4pu6rlu	581	1	Simple	simple	JJ
cord-353633-a4pu6rlu	581	2	noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	581	3	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	581	4	scoring	scoring	NN
cord-353633-a4pu6rlu	581	5	systems	system	NNS
cord-353633-a4pu6rlu	581	6	can	can	MD
cord-353633-a4pu6rlu	581	7	reliably	reliably	RB
cord-353633-a4pu6rlu	581	8	exclude	exclude	VB
cord-353633-a4pu6rlu	581	9	advanced	advanced	JJ
cord-353633-a4pu6rlu	581	10	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	581	11	in	in	IN
cord-353633-a4pu6rlu	581	12	patients	patient	NNS
cord-353633-a4pu6rlu	581	13	with	with	IN
cord-353633-a4pu6rlu	581	14	non	non	JJ
cord-353633-a4pu6rlu	581	15	-	-	JJ
cord-353633-a4pu6rlu	581	16	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	581	17	fatty	fatty	JJ
cord-353633-a4pu6rlu	581	18	liver	liver	NN
cord-353633-a4pu6rlu	581	19	disease	disease	NN
cord-353633-a4pu6rlu	581	20	Noninvasive	noninvasive	JJ
cord-353633-a4pu6rlu	581	21	markers	marker	NNS
cord-353633-a4pu6rlu	581	22	of	of	IN
cord-353633-a4pu6rlu	581	23	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	581	24	in	in	IN
cord-353633-a4pu6rlu	581	25	nonalcoholic	nonalcoholic	JJ
cord-353633-a4pu6rlu	581	26	fatty	fatty	JJ
cord-353633-a4pu6rlu	581	27	liver	liver	NN
cord-353633-a4pu6rlu	581	28	disease	disease	NN
cord-353633-a4pu6rlu	581	29	:	:	:
cord-353633-a4pu6rlu	581	30	Validating	validate	VBG
cord-353633-a4pu6rlu	581	31	the	the	DT
cord-353633-a4pu6rlu	581	32	European	European	NNP
cord-353633-a4pu6rlu	581	33	Liver	Liver	NNP
cord-353633-a4pu6rlu	581	34	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	581	35	Panel	Panel	NNP
cord-353633-a4pu6rlu	581	36	and	and	CC
cord-353633-a4pu6rlu	581	37	exploring	explore	VBG
cord-353633-a4pu6rlu	581	38	simple	simple	JJ
cord-353633-a4pu6rlu	581	39	markers	marker	NNS
cord-353633-a4pu6rlu	581	40	Hyaluronic	hyaluronic	NN
cord-353633-a4pu6rlu	581	41	acid	acid	NN
cord-353633-a4pu6rlu	581	42	,	,	,
cord-353633-a4pu6rlu	581	43	an	an	DT
cord-353633-a4pu6rlu	581	44	accurate	accurate	JJ
cord-353633-a4pu6rlu	581	45	serum	serum	NN
cord-353633-a4pu6rlu	581	46	marker	marker	NN
cord-353633-a4pu6rlu	581	47	for	for	IN
cord-353633-a4pu6rlu	581	48	severe	severe	JJ
cord-353633-a4pu6rlu	581	49	hepatic	hepatic	JJ
cord-353633-a4pu6rlu	581	50	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	581	51	in	in	IN
cord-353633-a4pu6rlu	581	52	patients	patient	NNS
cord-353633-a4pu6rlu	581	53	with	with	IN
cord-353633-a4pu6rlu	581	54	non	non	JJ
cord-353633-a4pu6rlu	581	55	-	-	JJ
cord-353633-a4pu6rlu	581	56	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	581	57	fatty	fatty	JJ
cord-353633-a4pu6rlu	581	58	liver	liver	NN
cord-353633-a4pu6rlu	581	59	disease	disease	NN
cord-353633-a4pu6rlu	581	60	Development	Development	NNP
cord-353633-a4pu6rlu	581	61	of	of	IN
cord-353633-a4pu6rlu	581	62	Serum	Serum	NNP
cord-353633-a4pu6rlu	581	63	Marker	Marker	NNP
cord-353633-a4pu6rlu	581	64	Models	model	NNS
cord-353633-a4pu6rlu	581	65	to	to	TO
cord-353633-a4pu6rlu	581	66	Increase	increase	VB
cord-353633-a4pu6rlu	581	67	Diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	581	68	Accuracy	Accuracy	NNP
cord-353633-a4pu6rlu	581	69	of	of	IN
cord-353633-a4pu6rlu	581	70	Advanced	Advanced	NNP
cord-353633-a4pu6rlu	581	71	Fibrosis	Fibrosis	NNP
cord-353633-a4pu6rlu	581	72	in	in	IN
cord-353633-a4pu6rlu	581	73	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	581	74	Fatty	Fatty	NNP
cord-353633-a4pu6rlu	581	75	Liver	Liver	NNP
cord-353633-a4pu6rlu	581	76	Disease	Disease	NNP
cord-353633-a4pu6rlu	581	77	:	:	:
cord-353633-a4pu6rlu	582	1	The	the	DT
cord-353633-a4pu6rlu	582	2	New	New	NNP
cord-353633-a4pu6rlu	582	3	LINKI	LINKI	NNP
cord-353633-a4pu6rlu	582	4	Algorithm	Algorithm	NNP
cord-353633-a4pu6rlu	583	1	Compared	compare	VBN
cord-353633-a4pu6rlu	583	2	with	with	IN
cord-353633-a4pu6rlu	583	3	Established	Established	NNP
cord-353633-a4pu6rlu	583	4	Algorithms	Algorithms	NNP
cord-353633-a4pu6rlu	583	5	Classification	Classification	NNP
cord-353633-a4pu6rlu	583	6	of	of	IN
cord-353633-a4pu6rlu	583	7	patients	patient	NNS
cord-353633-a4pu6rlu	583	8	with	with	IN
cord-353633-a4pu6rlu	583	9	non	non	JJ
cord-353633-a4pu6rlu	583	10	-	-	JJ
cord-353633-a4pu6rlu	583	11	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	583	12	fatty	fatty	JJ
cord-353633-a4pu6rlu	583	13	liver	liver	NN
cord-353633-a4pu6rlu	583	14	disease	disease	NN
cord-353633-a4pu6rlu	583	15	using	use	VBG
cord-353633-a4pu6rlu	583	16	rapid	rapid	JJ
cord-353633-a4pu6rlu	583	17	immunoassay	immunoassay	NN
cord-353633-a4pu6rlu	583	18	of	of	IN
cord-353633-a4pu6rlu	583	19	serum	serum	NN
cord-353633-a4pu6rlu	583	20	type	type	NN
cord-353633-a4pu6rlu	583	21	IV	IV	NNP
cord-353633-a4pu6rlu	583	22	collagen	collagen	NN
cord-353633-a4pu6rlu	583	23	compared	compare	VBN
cord-353633-a4pu6rlu	583	24	with	with	IN
cord-353633-a4pu6rlu	583	25	liver	liver	NN
cord-353633-a4pu6rlu	583	26	histology	histology	NN
cord-353633-a4pu6rlu	583	27	and	and	CC
cord-353633-a4pu6rlu	583	28	other	other	JJ
cord-353633-a4pu6rlu	583	29	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	583	30	markers	marker	NNS
cord-353633-a4pu6rlu	584	1	A	a	DT
cord-353633-a4pu6rlu	584	2	PDGFRbeta	pdgfrbeta	NN
cord-353633-a4pu6rlu	584	3	-	-	HYPH
cord-353633-a4pu6rlu	584	4	based	base	VBN
cord-353633-a4pu6rlu	584	5	score	score	NN
cord-353633-a4pu6rlu	584	6	predicts	predict	VBZ
cord-353633-a4pu6rlu	584	7	significant	significant	JJ
cord-353633-a4pu6rlu	584	8	liver	liver	NN
cord-353633-a4pu6rlu	584	9	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	584	10	in	in	IN
cord-353633-a4pu6rlu	584	11	patients	patient	NNS
cord-353633-a4pu6rlu	584	12	with	with	IN
cord-353633-a4pu6rlu	584	13	chronic	chronic	JJ
cord-353633-a4pu6rlu	584	14	alcohol	alcohol	NN
cord-353633-a4pu6rlu	584	15	abuse	abuse	NN
cord-353633-a4pu6rlu	584	16	,	,	,
cord-353633-a4pu6rlu	584	17	NAFLD	NAFLD	NNP
cord-353633-a4pu6rlu	584	18	and	and	CC
cord-353633-a4pu6rlu	584	19	viral	viral	JJ
cord-353633-a4pu6rlu	584	20	liver	liver	NN
cord-353633-a4pu6rlu	584	21	disease	disease	NN
cord-353633-a4pu6rlu	585	1	An	an	DT
cord-353633-a4pu6rlu	585	2	Evaluation	Evaluation	NNP
cord-353633-a4pu6rlu	585	3	of	of	IN
cord-353633-a4pu6rlu	585	4	the	the	DT
cord-353633-a4pu6rlu	585	5	Collagen	Collagen	NNP
cord-353633-a4pu6rlu	585	6	Fragments	fragment	NNS
cord-353633-a4pu6rlu	585	7	Related	relate	VBN
cord-353633-a4pu6rlu	585	8	to	to	IN
cord-353633-a4pu6rlu	585	9	Fibrogenesis	Fibrogenesis	NNP
cord-353633-a4pu6rlu	585	10	and	and	CC
cord-353633-a4pu6rlu	585	11	Fibrolysis	Fibrolysis	NNP
cord-353633-a4pu6rlu	585	12	in	in	IN
cord-353633-a4pu6rlu	585	13	Nonalcoholic	Nonalcoholic	NNP
cord-353633-a4pu6rlu	585	14	Steatohepatitis	Steatohepatitis	NNP
cord-353633-a4pu6rlu	586	1	A	a	DT
cord-353633-a4pu6rlu	586	2	gene	gene	NN
cord-353633-a4pu6rlu	586	3	-	-	HYPH
cord-353633-a4pu6rlu	586	4	based	base	VBN
cord-353633-a4pu6rlu	586	5	model	model	NN
cord-353633-a4pu6rlu	586	6	for	for	IN
cord-353633-a4pu6rlu	586	7	staging	stage	VBG
cord-353633-a4pu6rlu	586	8	liver	liver	NN
cord-353633-a4pu6rlu	586	9	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	587	1	A	a	DT
cord-353633-a4pu6rlu	587	2	biomarker	biomarker	NN
cord-353633-a4pu6rlu	587	3	panel	panel	NN
cord-353633-a4pu6rlu	587	4	for	for	IN
cord-353633-a4pu6rlu	587	5	non	non	JJ
cord-353633-a4pu6rlu	587	6	-	-	JJ
cord-353633-a4pu6rlu	587	7	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	587	8	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	587	9	(	(	-LRB-
cord-353633-a4pu6rlu	587	10	NASH	NASH	NNP
cord-353633-a4pu6rlu	587	11	)	)	-RRB-
cord-353633-a4pu6rlu	587	12	and	and	CC
cord-353633-a4pu6rlu	588	1	NASH	NASH	NNP
cord-353633-a4pu6rlu	588	2	-	-	HYPH
cord-353633-a4pu6rlu	588	3	related	relate	VBN
cord-353633-a4pu6rlu	588	4	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	589	1	New	new	JJ
cord-353633-a4pu6rlu	589	2	discriminant	discriminant	JJ
cord-353633-a4pu6rlu	589	3	score	score	NN
cord-353633-a4pu6rlu	589	4	to	to	TO
cord-353633-a4pu6rlu	589	5	predict	predict	VB
cord-353633-a4pu6rlu	589	6	the	the	DT
cord-353633-a4pu6rlu	589	7	fibrotic	fibrotic	JJ
cord-353633-a4pu6rlu	589	8	stage	stage	NN
cord-353633-a4pu6rlu	589	9	of	of	IN
cord-353633-a4pu6rlu	589	10	non	non	JJ
cord-353633-a4pu6rlu	589	11	-	-	JJ
cord-353633-a4pu6rlu	589	12	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	589	13	steatohepatitis	steatohepatitis	NN
cord-353633-a4pu6rlu	589	14	in	in	IN
cord-353633-a4pu6rlu	589	15	Japan	Japan	NNP
cord-353633-a4pu6rlu	590	1	The	the	DT
cord-353633-a4pu6rlu	590	2	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	590	3	accuracy	accuracy	NN
cord-353633-a4pu6rlu	590	4	of	of	IN
cord-353633-a4pu6rlu	590	5	liver	liver	NN
cord-353633-a4pu6rlu	590	6	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	590	7	in	in	IN
cord-353633-a4pu6rlu	590	8	non	non	JJ
cord-353633-a4pu6rlu	590	9	-	-	JJ
cord-353633-a4pu6rlu	590	10	viral	viral	JJ
cord-353633-a4pu6rlu	590	11	liver	liver	NN
cord-353633-a4pu6rlu	590	12	diseases	disease	NNS
cord-353633-a4pu6rlu	590	13	using	use	VBG
cord-353633-a4pu6rlu	590	14	acoustic	acoustic	JJ
cord-353633-a4pu6rlu	590	15	radiation	radiation	NN
cord-353633-a4pu6rlu	590	16	force	force	NN
cord-353633-a4pu6rlu	590	17	impulse	impulse	NN
cord-353633-a4pu6rlu	590	18	elastography	elastography	NNP
cord-353633-a4pu6rlu	590	19	:	:	:
cord-353633-a4pu6rlu	590	20	A	a	DT
cord-353633-a4pu6rlu	590	21	systematic	systematic	JJ
cord-353633-a4pu6rlu	590	22	review	review	NN
cord-353633-a4pu6rlu	590	23	and	and	CC
cord-353633-a4pu6rlu	590	24	meta	meta	NNP
cord-353633-a4pu6rlu	590	25	-	-	HYPH
cord-353633-a4pu6rlu	590	26	analysis	analysis	NN
cord-353633-a4pu6rlu	590	27	Magnetic	magnetic	JJ
cord-353633-a4pu6rlu	590	28	resonance	resonance	NN
cord-353633-a4pu6rlu	590	29	elastography	elastography	NN
cord-353633-a4pu6rlu	590	30	for	for	IN
cord-353633-a4pu6rlu	590	31	staging	stage	VBG
cord-353633-a4pu6rlu	590	32	liver	liver	NN
cord-353633-a4pu6rlu	590	33	fibrosis	fibrosis	NN
cord-353633-a4pu6rlu	590	34	in	in	IN
cord-353633-a4pu6rlu	590	35	non	non	JJ
cord-353633-a4pu6rlu	590	36	-	-	JJ
cord-353633-a4pu6rlu	590	37	alcoholic	alcoholic	JJ
cord-353633-a4pu6rlu	590	38	fatty	fatty	JJ
cord-353633-a4pu6rlu	590	39	liver	liver	NN
cord-353633-a4pu6rlu	590	40	disease	disease	NN
cord-353633-a4pu6rlu	590	41	:	:	:
cord-353633-a4pu6rlu	590	42	a	a	DT
cord-353633-a4pu6rlu	590	43	diagnostic	diagnostic	JJ
cord-353633-a4pu6rlu	590	44	accuracy	accuracy	NN
cord-353633-a4pu6rlu	590	45	systematic	systematic	JJ
cord-353633-a4pu6rlu	590	46	review	review	NN
cord-353633-a4pu6rlu	590	47	and	and	CC
cord-353633-a4pu6rlu	590	48	individual	individual	JJ
cord-353633-a4pu6rlu	590	49	participant	participant	NN
cord-353633-a4pu6rlu	590	50	data	datum	NNS
cord-353633-a4pu6rlu	590	51	pooled	pool	VBD
cord-353633-a4pu6rlu	590	52	analysis	analysis	NN