id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-000575-g1ob16b9	Xie, Xiao-li	Protein sequence analysis based on hydropathy profile of amino acids	2012-01-27		.txt	text/plain	2178	116	48	A new method to analyze the similarity/dissimilarity of protein sequence was proposed based on the conditional probability of the protein sequence. Based on the graphical representation, it is possible to numerically characterize DNA sequence and further quantitatively measure similarity of different DNA sequences. This is mainly because extension of DNA graphical representation to protein sequences would enormously increase the number of possible alternative assignments for the 20 amino acids. The graphical representation of protein sequence cannot only describe amino acid sequence, but also measure similarity/ dissimilarity of different protein sequences. In this paper, we converted a protein sequence into three-letter sequence based on hydropathy profile of amino acid and defined the three curves to represent different hydropathy features. The method is based on the graphical representation and conditional probability taken as the numerical characterization of the protein sequence. Similarity/dissimilarity studies of protein sequences based on a new 2D graphical representation	./cache/cord-000575-g1ob16b9.txt	./txt/cord-000575-g1ob16b9.txt