id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-189561-jhvwozsn	Chechetkin, Vladimr R.	Combining Detection and Reconstruction of Periodic Motifs in Genomic Sequences with Transitional Genome Mapping	2020-10-14		.txt	text/plain	4184	268	54	A method of transitional automorphic mapping of the genome on itself (TAMGI) is aimed at combining detection and reconstruction of periodic motifs in the genomic RNA/DNA sequences. Generally, TAMGI provides a convenient tool for the study of numerous molecular mechanisms with participation of both quasi-periodic motifs and complete repeats, the genome organization, contextual analysis of cis/trans regulatory elements, data mining, and correlations in the genomic sequences. f The distribution of k-mer lengths after TAMGI for the steps within interval 1-500 for the genome of SARS-CoV-2 (shown by crosses) and its comparison with the counterpart distribution for a random reshuffled sequence (shown by circles). The correspondence should be searched between the (generally multiple) elements of icosahedral symmetry and the character of large-scale quasi-periodic segmentation induced by weakly specific cooperative interactions between genomic RNA/DNA and capsid proteins. To sum up, TAMGI method developed in this article is quite general and can be applied to the combined detection/reconstruction of quasi-periodic motifs in the genomic RNA/DNA sequences.	./cache/cord-189561-jhvwozsn.txt	./txt/cord-189561-jhvwozsn.txt