id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334894-v5mu9ey2	Gaykwad, C.	Amelioration of oxidative stress using N‐acetylcysteine in canine parvoviral enteritis	2017-07-12		.txt	text/plain	3927	209	45	In this study, antioxidant potential of N‐acetylcysteine (NAC) in dogs infected with canine parvovirus with a nonblinded randomized clinical trial has been carried out. In addition, NAC treatment significantly improved glutathione S‐transferase (GST) activity and decreased nitrite plus nitrate (NOx) and malondialdehyde (MDA) concentrations on day 3 and 5 compared to supportive treatment in parvo‐infected dogs. The results of this study suggest that NAC represents a potential additional treatment option that could be considered to improve the health condition and minimize the duration of hospitalization in case of canine parvoviral diarrhea. Recently, it has been observed that parvovirus infection is linked with oxidative stress, and marked enhancement of reactive oxygen/nitrogen species, lipid peroxidation, DNA damage and poor antioxidant reserve (Luo & Qiu, 2013; Nykky, Vuento, & Gilbert, 2014; Panda, Patra, Nandi, & Swarup, 2009) . A strong association of CPV with oxidative stress suggests incorporation of antioxidants in therapeutic regimen in canine parvoviral diarrhea may help in ameliorating the clinical signs.	./cache/cord-334894-v5mu9ey2.txt	./txt/cord-334894-v5mu9ey2.txt