id author title date pages extension mime words sentences flesch summary cache txt cord-007511-5d5authn Gil, JP CYP2C8 and antimalaria drug efficacy 2007-02-07 .txt text/plain 6628 363 47 By combining it with published in vitro pharmacodynamic and drug metabolism information, we review and predict the possible relevance, or lack of, of CYP2C8 polymorphisms in the present and future efficacy of amodiaquine. By combining it with published in vitro pharmacodynamic and drug metabolism information, we review and predict the possible relevance, or lack of, of CYP2C8 polymorphisms in the present and future efficacy of amodiaquine. This leaves drug therapy as the main tool for the global treatment and control of the disease, presently in the successful shape of the highly effective combination of artemisinine (ART) derivatives with longer half-life partners [4] . ./cache/cord-007511-5d5authn.txt ./txt/cord-007511-5d5authn.txt