id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-011129-btaxvmsr	Di Paola, Nicholas	Viral genomics in Ebola virus research	2020-05-04		.txt	text/plain	9440	433	37	Here, we review how recent advances in genomic technologies have shaped past and current responses to outbreaks of Ebola virus disease (EVD), including insights into filovirus diversity and evolution. After this identification, considerations other than sequencing speed (for example, sequencing accuracy and processivity) become paramount in determining virus transmission networks and in detecting changes in the viral genome (between cases in the current outbreak and between the current and previous outbreaks) that could subvert MCMs. However, whereas unbiased sequencing approaches using high fidelity platforms can lead to the discovery of co-infections and reveal important clinical considerations during the treatment of patients near the point of need, targeted methods of pathogen characterization using the portable sequencing platforms iSeq 100 and MiSeq (which use bait-enrichment techniques) and MinION (which uses amplicon sequencing) can still provide useful genomic data albeit with a lower sequencing output (that is, a lower number of reads) than unbiased sequencing.	./cache/cord-011129-btaxvmsr.txt	./txt/cord-011129-btaxvmsr.txt