id author title date pages extension mime words sentences flesch summary cache txt cord-288734-xinkqs6u Muñoz-Fontela, César Ebola Virus Disease in Humans: Pathophysiology and Immunity 2017-03-30 .txt text/plain 9957 451 44 Discovered in 1976 during the first documented outbreak of Ebola virus disease (EVD) in the town of Yambuku in northern Zaire (today Democratic Republic of the Congo), EBOV has since caused sporadic human disease outbreaks of varying magnitude in Equatorial African countries (Sanchez et al. Antigen-presenting cells are a putative initial target of EBOV infection and previous research in animal models of disease has indicated that dendritic cells (DCs) and macrophages are early and preferred targets of EBOV and support virus replication (Geisbert et al. Clinical presentation, biochemical, and haematological parameters and their association with outcome in patients with Ebola virus disease: an observational cohort study Sequence-based human leukocyte antigen-B typing of patients infected with Ebola virus in Uganda in 2000: identification of alleles associated with fatal and nonfatal disease outcomes ./cache/cord-288734-xinkqs6u.txt ./txt/cord-288734-xinkqs6u.txt