id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-334560-1j9zmuub	Hunt, Catherine L.	Filovirus Entry: A Novelty in the Viral Fusion World	2012-02-07		.txt	text/plain	6445	301	48	Details of the molecular events following cathepsin-dependent trimming of GP(1) are currently incomplete; however, the processed GP(1) specifically interacts with endosomal/lysosomal membranes that contain the Niemann Pick C1 (NPC1) protein and expression of NPC1 is required for productive infection, suggesting that GP/NPC1 interactions may be an important late step in the entry process. However, for reasons that are not entirely clear, this type of study has not been successful in identifying cell surface proteins that directly interact with EBOV GP to mediate virus entry [41, 42] . However, as both of these regions can be deleted from EBOV GP 1 without loss of viral transduction efficiency [16, [50] [51] [52] , it is likely that C-type lectins increase filovirus attachment to cells rather than serving as cellular receptors that mediate internalization of the virus into endosomes [53] .	./cache/cord-334560-1j9zmuub.txt	./txt/cord-334560-1j9zmuub.txt