id author title date pages extension mime words sentences flesch summary cache txt cord-336986-rmxin1da De Clercq, Erik New Nucleoside Analogues for the Treatment of Hemorrhagic Fever Virus Infections 2019-08-07 .txt text/plain 2711 221 57 Eight different compounds, all nucleoside analogues, could presently be considered as potential drug candidates for the treatment of Ebola virus (EBOV) and/or other hemorrhagic fever virus (HFV) infections. Abstract: Eight differentc ompounds, all nucleoside analogues, could presently be considered as potential drug candidates for the treatment of Ebola virus (EBOV) and/oro ther hemorrhagic fever virus (HFV) infections.T hey can be considered as either (i)adenine analogues (3-deazaneplanocin A, galidesivir,G S-6620 andr emdesivir) or (ii)guanine analogues containing the carboxamide entity (ribavirin, EICAR, pyrazofurin and favipiravir). [26] It wasa lso found active against other emerging viruses such as respiratory syncytial virus (RSV) and hepatitis Cv irus (HCV),a nd the presence of the 1'-cyano group in remdesivir wasf ound to be critical in providing selectivity toward the viral (RNA) polymerases. ./cache/cord-336986-rmxin1da.txt ./txt/cord-336986-rmxin1da.txt