id	sid	tid	token	lemma	pos
cord-256187-ofp7tupv	1	1	key	key	JJ
cord-256187-ofp7tupv	2	1	:	:	:
cord-256187-ofp7tupv	2	2	cord-256187-ofp7tupv	cord-256187-ofp7tupv	NNP
cord-256187-ofp7tupv	2	3	authors	author	NNS
cord-256187-ofp7tupv	2	4	:	:	:
cord-256187-ofp7tupv	2	5	Kühl	Kühl	NNP
cord-256187-ofp7tupv	2	6	,	,	,
cord-256187-ofp7tupv	2	7	A.	a.	NN
cord-256187-ofp7tupv	2	8	;	;	:
cord-256187-ofp7tupv	2	9	Pöhlmann	Pöhlmann	NNP
cord-256187-ofp7tupv	2	10	,	,	,
cord-256187-ofp7tupv	2	11	S.	S.	NNP
cord-256187-ofp7tupv	2	12	title	title	NN
cord-256187-ofp7tupv	2	13	:	:	:
cord-256187-ofp7tupv	2	14	How	how	WRB
cord-256187-ofp7tupv	2	15	Ebola	Ebola	NNP
cord-256187-ofp7tupv	2	16	Virus	Virus	NNP
cord-256187-ofp7tupv	2	17	Counters	counter	VBZ
cord-256187-ofp7tupv	2	18	the	the	DT
cord-256187-ofp7tupv	2	19	Interferon	Interferon	NNP
cord-256187-ofp7tupv	2	20	System	System	NNP
cord-256187-ofp7tupv	2	21	date	date	NN
cord-256187-ofp7tupv	2	22	:	:	:
cord-256187-ofp7tupv	2	23	2012	2012	CD
cord-256187-ofp7tupv	2	24	-	-	SYM
cord-256187-ofp7tupv	2	25	09	09	CD
cord-256187-ofp7tupv	2	26	-	-	HYPH
cord-256187-ofp7tupv	2	27	07	07	CD
cord-256187-ofp7tupv	2	28	journal	journal	NN
cord-256187-ofp7tupv	2	29	:	:	:
cord-256187-ofp7tupv	3	1	Zoonoses	Zoonoses	NNP
cord-256187-ofp7tupv	3	2	Public	Public	NNP
cord-256187-ofp7tupv	3	3	Health	Health	NNP
cord-256187-ofp7tupv	3	4	DOI	DOI	NNP
cord-256187-ofp7tupv	3	5	:	:	:
cord-256187-ofp7tupv	4	1	10.1111	10.1111	CD
cord-256187-ofp7tupv	4	2	/	/	SYM
cord-256187-ofp7tupv	4	3	j.1863	j.1863	NNP
cord-256187-ofp7tupv	4	4	-	-	HYPH
cord-256187-ofp7tupv	4	5	2378.2012.01454.x	2378.2012.01454.x	NNP
cord-256187-ofp7tupv	5	1	sha	sha	NNP
cord-256187-ofp7tupv	5	2	:	:	:
cord-256187-ofp7tupv	6	1	e90edd075fd1c05194acb4b12d0f7499cf9853b8	e90edd075fd1c05194acb4b12d0f7499cf9853b8	NNP
cord-256187-ofp7tupv	6	2	doc_id	doc_id	CD
cord-256187-ofp7tupv	7	1	:	:	:
cord-256187-ofp7tupv	7	2	256187	256187	CD
cord-256187-ofp7tupv	7	3	cord_uid	cord_uid	NNS
cord-256187-ofp7tupv	7	4	:	:	:
cord-256187-ofp7tupv	8	1	ofp7tupv	ofp7tupv	NNP
cord-256187-ofp7tupv	8	2	Zoonotic	zoonotic	JJ
cord-256187-ofp7tupv	8	3	transmission	transmission	NN
cord-256187-ofp7tupv	8	4	of	of	IN
cord-256187-ofp7tupv	8	5	Ebola	Ebola	NNP
cord-256187-ofp7tupv	8	6	virus	virus	NN
cord-256187-ofp7tupv	8	7	(	(	-LRB-
cord-256187-ofp7tupv	8	8	EBOV	EBOV	NNP
cord-256187-ofp7tupv	8	9	)	)	-RRB-
cord-256187-ofp7tupv	8	10	to	to	IN
cord-256187-ofp7tupv	8	11	humans	human	NNS
cord-256187-ofp7tupv	8	12	causes	cause	VBZ
cord-256187-ofp7tupv	8	13	a	a	DT
cord-256187-ofp7tupv	8	14	severe	severe	JJ
cord-256187-ofp7tupv	8	15	haemorrhagic	haemorrhagic	JJ
cord-256187-ofp7tupv	8	16	fever	fever	NN
cord-256187-ofp7tupv	8	17	in	in	IN
cord-256187-ofp7tupv	8	18	afflicted	afflict	VBN
cord-256187-ofp7tupv	8	19	individuals	individual	NNS
cord-256187-ofp7tupv	8	20	with	with	IN
cord-256187-ofp7tupv	8	21	high	high	JJ
cord-256187-ofp7tupv	8	22	case‐fatality	case‐fatality	NN
cord-256187-ofp7tupv	8	23	rates	rate	NNS
cord-256187-ofp7tupv	8	24	.	.	.
cord-256187-ofp7tupv	9	1	Neither	neither	DT
cord-256187-ofp7tupv	9	2	vaccines	vaccine	NNS
cord-256187-ofp7tupv	9	3	nor	nor	CC
cord-256187-ofp7tupv	9	4	therapeutics	therapeutic	NNS
cord-256187-ofp7tupv	9	5	are	be	VBP
cord-256187-ofp7tupv	9	6	at	at	IN
cord-256187-ofp7tupv	9	7	present	present	JJ
cord-256187-ofp7tupv	9	8	available	available	JJ
cord-256187-ofp7tupv	9	9	to	to	TO
cord-256187-ofp7tupv	9	10	combat	combat	VB
cord-256187-ofp7tupv	9	11	EBOV	EBOV	NNP
cord-256187-ofp7tupv	9	12	infection	infection	NN
cord-256187-ofp7tupv	9	13	,	,	,
cord-256187-ofp7tupv	9	14	making	make	VBG
cord-256187-ofp7tupv	9	15	the	the	DT
cord-256187-ofp7tupv	9	16	virus	virus	NN
cord-256187-ofp7tupv	9	17	a	a	DT
cord-256187-ofp7tupv	9	18	potential	potential	JJ
cord-256187-ofp7tupv	9	19	threat	threat	NN
cord-256187-ofp7tupv	9	20	to	to	IN
cord-256187-ofp7tupv	9	21	public	public	JJ
cord-256187-ofp7tupv	9	22	health	health	NN
cord-256187-ofp7tupv	9	23	.	.	.
cord-256187-ofp7tupv	10	1	To	to	TO
cord-256187-ofp7tupv	10	2	devise	devise	VB
cord-256187-ofp7tupv	10	3	antiviral	antiviral	JJ
cord-256187-ofp7tupv	10	4	strategies	strategy	NNS
cord-256187-ofp7tupv	10	5	,	,	,
cord-256187-ofp7tupv	10	6	it	-PRON-	PRP
cord-256187-ofp7tupv	10	7	is	be	VBZ
cord-256187-ofp7tupv	10	8	important	important	JJ
cord-256187-ofp7tupv	10	9	to	to	TO
cord-256187-ofp7tupv	10	10	understand	understand	VB
cord-256187-ofp7tupv	10	11	which	which	WDT
cord-256187-ofp7tupv	10	12	components	component	NNS
cord-256187-ofp7tupv	10	13	of	of	IN
cord-256187-ofp7tupv	10	14	the	the	DT
cord-256187-ofp7tupv	10	15	immune	immune	JJ
cord-256187-ofp7tupv	10	16	system	system	NN
cord-256187-ofp7tupv	10	17	could	could	MD
cord-256187-ofp7tupv	10	18	be	be	VB
cord-256187-ofp7tupv	10	19	effective	effective	JJ
cord-256187-ofp7tupv	10	20	against	against	IN
cord-256187-ofp7tupv	10	21	EBOV	EBOV	NNP
cord-256187-ofp7tupv	10	22	infection	infection	NN
cord-256187-ofp7tupv	10	23	.	.	.
cord-256187-ofp7tupv	11	1	The	the	DT
cord-256187-ofp7tupv	11	2	interferon	interferon	NN
cord-256187-ofp7tupv	11	3	(	(	-LRB-
cord-256187-ofp7tupv	11	4	IFN	IFN	NNP
cord-256187-ofp7tupv	11	5	)	)	-RRB-
cord-256187-ofp7tupv	11	6	system	system	NN
cord-256187-ofp7tupv	11	7	constitutes	constitute	VBZ
cord-256187-ofp7tupv	11	8	a	a	DT
cord-256187-ofp7tupv	11	9	key	key	JJ
cord-256187-ofp7tupv	11	10	innate	innate	JJ
cord-256187-ofp7tupv	11	11	defence	defence	NN
cord-256187-ofp7tupv	11	12	against	against	IN
cord-256187-ofp7tupv	11	13	viral	viral	JJ
cord-256187-ofp7tupv	11	14	infections	infection	NNS
cord-256187-ofp7tupv	11	15	and	and	CC
cord-256187-ofp7tupv	11	16	prevents	prevent	VBZ
cord-256187-ofp7tupv	11	17	development	development	NN
cord-256187-ofp7tupv	11	18	of	of	IN
cord-256187-ofp7tupv	11	19	lethal	lethal	JJ
cord-256187-ofp7tupv	11	20	disease	disease	NN
cord-256187-ofp7tupv	11	21	in	in	IN
cord-256187-ofp7tupv	11	22	mice	mouse	NNS
cord-256187-ofp7tupv	11	23	infected	infect	VBN
cord-256187-ofp7tupv	11	24	with	with	IN
cord-256187-ofp7tupv	11	25	EBOV	EBOV	NNP
cord-256187-ofp7tupv	11	26	strains	strain	NNS
cord-256187-ofp7tupv	11	27	not	not	RB
cord-256187-ofp7tupv	11	28	adapted	adapt	VBN
cord-256187-ofp7tupv	11	29	to	to	IN
cord-256187-ofp7tupv	11	30	this	this	DT
cord-256187-ofp7tupv	11	31	host	host	NN
cord-256187-ofp7tupv	11	32	.	.	.
cord-256187-ofp7tupv	12	1	Recent	recent	JJ
cord-256187-ofp7tupv	12	2	research	research	NN
cord-256187-ofp7tupv	12	3	revealed	reveal	VBD
cord-256187-ofp7tupv	12	4	that	that	IN
cord-256187-ofp7tupv	12	5	expression	expression	NN
cord-256187-ofp7tupv	12	6	of	of	IN
cord-256187-ofp7tupv	12	7	the	the	DT
cord-256187-ofp7tupv	12	8	host	host	NN
cord-256187-ofp7tupv	12	9	cell	cell	NN
cord-256187-ofp7tupv	12	10	IFN‐inducible	ifn‐inducible	NN
cord-256187-ofp7tupv	12	11	transmembrane	transmembrane	NN
cord-256187-ofp7tupv	12	12	proteins	protein	NNS
cord-256187-ofp7tupv	12	13	1–3	1–3	CD
cord-256187-ofp7tupv	12	14	(	(	-LRB-
cord-256187-ofp7tupv	12	15	IFITM1–3	IFITM1–3	NNP
cord-256187-ofp7tupv	12	16	)	)	-RRB-
cord-256187-ofp7tupv	12	17	and	and	CC
cord-256187-ofp7tupv	12	18	tetherin	tetherin	NNP
cord-256187-ofp7tupv	12	19	is	be	VBZ
cord-256187-ofp7tupv	12	20	induced	induce	VBN
cord-256187-ofp7tupv	12	21	by	by	IN
cord-256187-ofp7tupv	12	22	IFN	IFN	NNP
cord-256187-ofp7tupv	12	23	and	and	CC
cord-256187-ofp7tupv	12	24	restricts	restrict	VBZ
cord-256187-ofp7tupv	12	25	EBOV	EBOV	NNP
cord-256187-ofp7tupv	12	26	infection	infection	NN
cord-256187-ofp7tupv	12	27	,	,	,
cord-256187-ofp7tupv	12	28	at	at	IN
cord-256187-ofp7tupv	12	29	least	least	JJS
cord-256187-ofp7tupv	12	30	in	in	IN
cord-256187-ofp7tupv	12	31	cell	cell	NN
cord-256187-ofp7tupv	12	32	culture	culture	NN
cord-256187-ofp7tupv	12	33	model	model	NN
cord-256187-ofp7tupv	12	34	systems	system	NNS
cord-256187-ofp7tupv	12	35	.	.	.
cord-256187-ofp7tupv	13	1	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	13	2	,	,	,
cord-256187-ofp7tupv	13	3	tetherin	tetherin	NNP
cord-256187-ofp7tupv	13	4	and	and	CC
cord-256187-ofp7tupv	13	5	other	other	JJ
cord-256187-ofp7tupv	13	6	effector	effector	NN
cord-256187-ofp7tupv	13	7	molecules	molecule	NNS
cord-256187-ofp7tupv	13	8	of	of	IN
cord-256187-ofp7tupv	13	9	the	the	DT
cord-256187-ofp7tupv	13	10	IFN	IFN	NNP
cord-256187-ofp7tupv	13	11	system	system	NN
cord-256187-ofp7tupv	13	12	could	could	MD
cord-256187-ofp7tupv	13	13	thus	thus	RB
cord-256187-ofp7tupv	13	14	pose	pose	VB
cord-256187-ofp7tupv	13	15	a	a	DT
cord-256187-ofp7tupv	13	16	potent	potent	JJ
cord-256187-ofp7tupv	13	17	barrier	barrier	NN
cord-256187-ofp7tupv	13	18	against	against	IN
cord-256187-ofp7tupv	13	19	EBOV	EBOV	NNP
cord-256187-ofp7tupv	13	20	spread	spread	VBD
cord-256187-ofp7tupv	13	21	in	in	IN
cord-256187-ofp7tupv	13	22	humans	human	NNS
cord-256187-ofp7tupv	13	23	.	.	.
cord-256187-ofp7tupv	14	1	However	however	RB
cord-256187-ofp7tupv	14	2	,	,	,
cord-256187-ofp7tupv	14	3	EBOV	EBOV	NNP
cord-256187-ofp7tupv	14	4	interferes	interfere	VBZ
cord-256187-ofp7tupv	14	5	with	with	IN
cord-256187-ofp7tupv	14	6	signalling	signal	VBG
cord-256187-ofp7tupv	14	7	events	event	NNS
cord-256187-ofp7tupv	14	8	required	require	VBN
cord-256187-ofp7tupv	14	9	for	for	IN
cord-256187-ofp7tupv	14	10	human	human	JJ
cord-256187-ofp7tupv	14	11	cells	cell	NNS
cord-256187-ofp7tupv	14	12	to	to	TO
cord-256187-ofp7tupv	14	13	express	express	VB
cord-256187-ofp7tupv	14	14	these	these	DT
cord-256187-ofp7tupv	14	15	proteins	protein	NNS
cord-256187-ofp7tupv	14	16	.	.	.
cord-256187-ofp7tupv	15	1	Here	here	RB
cord-256187-ofp7tupv	15	2	,	,	,
cord-256187-ofp7tupv	15	3	we	-PRON-	PRP
cord-256187-ofp7tupv	15	4	will	will	MD
cord-256187-ofp7tupv	15	5	review	review	VB
cord-256187-ofp7tupv	15	6	the	the	DT
cord-256187-ofp7tupv	15	7	strategies	strategy	NNS
cord-256187-ofp7tupv	15	8	employed	employ	VBN
cord-256187-ofp7tupv	15	9	by	by	IN
cord-256187-ofp7tupv	15	10	EBOV	EBOV	NNP
cord-256187-ofp7tupv	15	11	to	to	TO
cord-256187-ofp7tupv	15	12	fight	fight	VB
cord-256187-ofp7tupv	15	13	the	the	DT
cord-256187-ofp7tupv	15	14	IFN	IFN	NNP
cord-256187-ofp7tupv	15	15	system	system	NN
cord-256187-ofp7tupv	15	16	,	,	,
cord-256187-ofp7tupv	15	17	and	and	CC
cord-256187-ofp7tupv	15	18	we	-PRON-	PRP
cord-256187-ofp7tupv	15	19	will	will	MD
cord-256187-ofp7tupv	15	20	discuss	discuss	VB
cord-256187-ofp7tupv	15	21	how	how	WRB
cord-256187-ofp7tupv	15	22	IFITM	IFITM	NNP
cord-256187-ofp7tupv	15	23	proteins	protein	NNS
cord-256187-ofp7tupv	15	24	and	and	CC
cord-256187-ofp7tupv	15	25	tetherin	tetherin	NN
cord-256187-ofp7tupv	15	26	inhibit	inhibit	VBP
cord-256187-ofp7tupv	15	27	EBOV	EBOV	NNP
cord-256187-ofp7tupv	15	28	infection	infection	NN
cord-256187-ofp7tupv	15	29	.	.	.
cord-256187-ofp7tupv	16	1	The	the	DT
cord-256187-ofp7tupv	16	2	Ebola	Ebola	NNP
cord-256187-ofp7tupv	16	3	virus	virus	NN
cord-256187-ofp7tupv	16	4	(	(	-LRB-
cord-256187-ofp7tupv	16	5	EBOV	EBOV	NNP
cord-256187-ofp7tupv	16	6	)	)	-RRB-
cord-256187-ofp7tupv	16	7	is	be	VBZ
cord-256187-ofp7tupv	16	8	an	an	DT
cord-256187-ofp7tupv	16	9	enveloped	envelop	VBN
cord-256187-ofp7tupv	16	10	,	,	,
cord-256187-ofp7tupv	16	11	negativestranded	negativestranded	JJ
cord-256187-ofp7tupv	16	12	RNA	RNA	NNP
cord-256187-ofp7tupv	16	13	virus	virus	NN
cord-256187-ofp7tupv	16	14	of	of	IN
cord-256187-ofp7tupv	16	15	the	the	DT
cord-256187-ofp7tupv	16	16	filovirus	filovirus	NN
cord-256187-ofp7tupv	16	17	family	family	NN
cord-256187-ofp7tupv	16	18	.	.	.
cord-256187-ofp7tupv	17	1	Infection	infection	NN
cord-256187-ofp7tupv	17	2	of	of	IN
cord-256187-ofp7tupv	17	3	humans	human	NNS
cord-256187-ofp7tupv	17	4	with	with	IN
cord-256187-ofp7tupv	17	5	EBOV	EBOV	NNP
cord-256187-ofp7tupv	17	6	causes	cause	VBZ
cord-256187-ofp7tupv	17	7	Ebola	Ebola	NNP
cord-256187-ofp7tupv	17	8	haemorrhagic	haemorrhagic	JJ
cord-256187-ofp7tupv	17	9	fever	fever	NN
cord-256187-ofp7tupv	17	10	.	.	.
cord-256187-ofp7tupv	18	1	At	at	IN
cord-256187-ofp7tupv	18	2	present	present	NN
cord-256187-ofp7tupv	18	3	,	,	,
cord-256187-ofp7tupv	18	4	neither	neither	CC
cord-256187-ofp7tupv	18	5	antivirals	antiviral	NNS
cord-256187-ofp7tupv	18	6	nor	nor	CC
cord-256187-ofp7tupv	18	7	vaccines	vaccine	NNS
cord-256187-ofp7tupv	18	8	are	be	VBP
cord-256187-ofp7tupv	18	9	available	available	JJ
cord-256187-ofp7tupv	18	10	to	to	TO
cord-256187-ofp7tupv	18	11	combat	combat	VB
cord-256187-ofp7tupv	18	12	this	this	DT
cord-256187-ofp7tupv	18	13	lethal	lethal	JJ
cord-256187-ofp7tupv	18	14	disease	disease	NN
cord-256187-ofp7tupv	18	15	,	,	,
cord-256187-ofp7tupv	18	16	and	and	CC
cord-256187-ofp7tupv	18	17	EBOV	EBOV	NNP
cord-256187-ofp7tupv	18	18	is	be	VBZ
cord-256187-ofp7tupv	18	19	classified	classify	VBN
cord-256187-ofp7tupv	18	20	as	as	IN
cord-256187-ofp7tupv	18	21	a	a	DT
cord-256187-ofp7tupv	18	22	category	category	NN
cord-256187-ofp7tupv	18	23	A	a	DT
cord-256187-ofp7tupv	18	24	priority	priority	NN
cord-256187-ofp7tupv	18	25	pathogen	pathogen	NN
cord-256187-ofp7tupv	18	26	(	(	-LRB-
cord-256187-ofp7tupv	18	27	NIAID	NIAID	NNP
cord-256187-ofp7tupv	18	28	,	,	,
cord-256187-ofp7tupv	18	29	2011	2011	CD
cord-256187-ofp7tupv	18	30	)	)	-RRB-
cord-256187-ofp7tupv	18	31	.	.	.
cord-256187-ofp7tupv	19	1	Four	four	CD
cord-256187-ofp7tupv	19	2	EBOV	EBOV	NNP
cord-256187-ofp7tupv	19	3	species	specie	NNS
cord-256187-ofp7tupv	19	4	have	have	VBP
cord-256187-ofp7tupv	19	5	been	be	VBN
cord-256187-ofp7tupv	19	6	defined	define	VBN
cord-256187-ofp7tupv	19	7	(	(	-LRB-
cord-256187-ofp7tupv	19	8	Kuhn	Kuhn	NNP
cord-256187-ofp7tupv	19	9	,	,	,
cord-256187-ofp7tupv	19	10	2008	2008	CD
cord-256187-ofp7tupv	19	11	)	)	-RRB-
cord-256187-ofp7tupv	19	12	,	,	,
cord-256187-ofp7tupv	19	13	Zaire	Zaire	NNP
cord-256187-ofp7tupv	19	14	ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	19	15	(	(	-LRB-
cord-256187-ofp7tupv	19	16	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	19	17	)	)	-RRB-
cord-256187-ofp7tupv	19	18	,	,	,
cord-256187-ofp7tupv	19	19	Sudan	Sudan	NNP
cord-256187-ofp7tupv	19	20	ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	19	21	(	(	-LRB-
cord-256187-ofp7tupv	19	22	SEBOV	SEBOV	NNP
cord-256187-ofp7tupv	19	23	)	)	-RRB-
cord-256187-ofp7tupv	19	24	,	,	.
cord-256187-ofp7tupv	20	1	Côte	Côte	NNP
cord-256187-ofp7tupv	20	2	d'Ivoire	d'Ivoire	NNP
cord-256187-ofp7tupv	20	3	ebolavirus	ebolavirus	NNP
cord-256187-ofp7tupv	20	4	(	(	-LRB-
cord-256187-ofp7tupv	20	5	CIEBOV	CIEBOV	NNP
cord-256187-ofp7tupv	20	6	)	)	-RRB-
cord-256187-ofp7tupv	20	7	and	and	CC
cord-256187-ofp7tupv	20	8	Reston	Reston	NNP
cord-256187-ofp7tupv	20	9	ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	20	10	(	(	-LRB-
cord-256187-ofp7tupv	20	11	REBOV	REBOV	NNP
cord-256187-ofp7tupv	20	12	)	)	-RRB-
cord-256187-ofp7tupv	20	13	,	,	,
cord-256187-ofp7tupv	20	14	and	and	CC
cord-256187-ofp7tupv	20	15	a	a	DT
cord-256187-ofp7tupv	20	16	fifth	fifth	JJ
cord-256187-ofp7tupv	20	17	species	specie	NNS
cord-256187-ofp7tupv	20	18	has	have	VBZ
cord-256187-ofp7tupv	20	19	been	be	VBN
cord-256187-ofp7tupv	20	20	proposed	propose	VBN
cord-256187-ofp7tupv	20	21	,	,	,
cord-256187-ofp7tupv	20	22	Bundibugyo	Bundibugyo	NNP
cord-256187-ofp7tupv	20	23	ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	20	24	(	(	-LRB-
cord-256187-ofp7tupv	20	25	BEBOV	BEBOV	NNP
cord-256187-ofp7tupv	20	26	)	)	-RRB-
cord-256187-ofp7tupv	21	1	(	(	-LRB-
cord-256187-ofp7tupv	21	2	Towner	Towner	NNP
cord-256187-ofp7tupv	21	3	et	et	NNP
cord-256187-ofp7tupv	21	4	al	al	NNP
cord-256187-ofp7tupv	21	5	.	.	NNP
cord-256187-ofp7tupv	21	6	,	,	,
cord-256187-ofp7tupv	21	7	2008	2008	CD
cord-256187-ofp7tupv	21	8	)	)	-RRB-
cord-256187-ofp7tupv	21	9	.	.	.
cord-256187-ofp7tupv	22	1	African	african	JJ
cord-256187-ofp7tupv	22	2	fruit	fruit	NN
cord-256187-ofp7tupv	22	3	bats	bat	NNS
cord-256187-ofp7tupv	22	4	are	be	VBP
cord-256187-ofp7tupv	22	5	a	a	DT
cord-256187-ofp7tupv	22	6	natural	natural	JJ
cord-256187-ofp7tupv	22	7	reservoir	reservoir	NN
cord-256187-ofp7tupv	22	8	of	of	IN
cord-256187-ofp7tupv	22	9	the	the	DT
cord-256187-ofp7tupv	22	10	second	second	JJ
cord-256187-ofp7tupv	22	11	filoviral	filoviral	JJ
cord-256187-ofp7tupv	22	12	genus	genus	NN
cord-256187-ofp7tupv	22	13	,	,	,
cord-256187-ofp7tupv	22	14	Marburg	Marburg	NNP
cord-256187-ofp7tupv	22	15	virus	virus	NN
cord-256187-ofp7tupv	22	16	(	(	-LRB-
cord-256187-ofp7tupv	22	17	MARV	MARV	NNP
cord-256187-ofp7tupv	22	18	)	)	-RRB-
cord-256187-ofp7tupv	22	19	,	,	,
cord-256187-ofp7tupv	22	20	and	and	CC
cord-256187-ofp7tupv	22	21	have	have	VBP
cord-256187-ofp7tupv	22	22	also	also	RB
cord-256187-ofp7tupv	22	23	been	be	VBN
cord-256187-ofp7tupv	22	24	proposed	propose	VBN
cord-256187-ofp7tupv	22	25	as	as	IN
cord-256187-ofp7tupv	22	26	a	a	DT
cord-256187-ofp7tupv	22	27	natural	natural	JJ
cord-256187-ofp7tupv	22	28	reservoir	reservoir	NN
cord-256187-ofp7tupv	22	29	of	of	IN
cord-256187-ofp7tupv	22	30	EBOV	EBOV	NNP
cord-256187-ofp7tupv	23	1	(	(	-LRB-
cord-256187-ofp7tupv	23	2	Leroy	Leroy	NNP
cord-256187-ofp7tupv	23	3	et	et	NNP
cord-256187-ofp7tupv	23	4	al	al	NNP
cord-256187-ofp7tupv	23	5	.	.	NNP
cord-256187-ofp7tupv	23	6	,	,	,
cord-256187-ofp7tupv	23	7	2005	2005	CD
cord-256187-ofp7tupv	23	8	)	)	-RRB-
cord-256187-ofp7tupv	23	9	.	.	.
cord-256187-ofp7tupv	24	1	African	african	JJ
cord-256187-ofp7tupv	24	2	fruit	fruit	NN
cord-256187-ofp7tupv	24	3	bats	bat	NNS
cord-256187-ofp7tupv	24	4	may	may	MD
cord-256187-ofp7tupv	24	5	transmit	transmit	VB
cord-256187-ofp7tupv	24	6	the	the	DT
cord-256187-ofp7tupv	24	7	virus	virus	NN
cord-256187-ofp7tupv	24	8	to	to	IN
cord-256187-ofp7tupv	24	9	humans	human	NNS
cord-256187-ofp7tupv	24	10	either	either	CC
cord-256187-ofp7tupv	24	11	directly	directly	RB
cord-256187-ofp7tupv	24	12	or	or	CC
cord-256187-ofp7tupv	24	13	via	via	IN
cord-256187-ofp7tupv	24	14	an	an	DT
cord-256187-ofp7tupv	24	15	intermediate	intermediate	JJ
cord-256187-ofp7tupv	24	16	host	host	NN
cord-256187-ofp7tupv	25	1	(	(	-LRB-
cord-256187-ofp7tupv	25	2	Groseth	Groseth	NNP
cord-256187-ofp7tupv	25	3	et	et	FW
cord-256187-ofp7tupv	25	4	al	al	NNP
cord-256187-ofp7tupv	25	5	.	.	NNP
cord-256187-ofp7tupv	25	6	,	,	,
cord-256187-ofp7tupv	25	7	2007	2007	CD
cord-256187-ofp7tupv	25	8	)	)	-RRB-
cord-256187-ofp7tupv	25	9	.	.	.
cord-256187-ofp7tupv	26	1	Outbreaks	outbreak	NNS
cord-256187-ofp7tupv	26	2	of	of	IN
cord-256187-ofp7tupv	26	3	Summary	Summary	NNP
cord-256187-ofp7tupv	26	4	Zoonotic	Zoonotic	NNP
cord-256187-ofp7tupv	26	5	transmission	transmission	NN
cord-256187-ofp7tupv	26	6	of	of	IN
cord-256187-ofp7tupv	26	7	Ebola	Ebola	NNP
cord-256187-ofp7tupv	26	8	virus	virus	NN
cord-256187-ofp7tupv	26	9	(	(	-LRB-
cord-256187-ofp7tupv	26	10	EBOV	EBOV	NNP
cord-256187-ofp7tupv	26	11	)	)	-RRB-
cord-256187-ofp7tupv	26	12	to	to	IN
cord-256187-ofp7tupv	26	13	humans	human	NNS
cord-256187-ofp7tupv	26	14	causes	cause	VBZ
cord-256187-ofp7tupv	26	15	a	a	DT
cord-256187-ofp7tupv	26	16	severe	severe	JJ
cord-256187-ofp7tupv	26	17	haemorrhagic	haemorrhagic	JJ
cord-256187-ofp7tupv	26	18	fever	fever	NN
cord-256187-ofp7tupv	26	19	in	in	IN
cord-256187-ofp7tupv	26	20	afflicted	afflict	VBN
cord-256187-ofp7tupv	26	21	individuals	individual	NNS
cord-256187-ofp7tupv	26	22	with	with	IN
cord-256187-ofp7tupv	26	23	high	high	JJ
cord-256187-ofp7tupv	26	24	case	case	NN
cord-256187-ofp7tupv	26	25	-	-	HYPH
cord-256187-ofp7tupv	26	26	fatality	fatality	NN
cord-256187-ofp7tupv	26	27	rates	rate	NNS
cord-256187-ofp7tupv	26	28	.	.	.
cord-256187-ofp7tupv	27	1	Neither	neither	DT
cord-256187-ofp7tupv	27	2	vaccines	vaccine	NNS
cord-256187-ofp7tupv	27	3	nor	nor	CC
cord-256187-ofp7tupv	27	4	therapeutics	therapeutic	NNS
cord-256187-ofp7tupv	27	5	are	be	VBP
cord-256187-ofp7tupv	27	6	at	at	IN
cord-256187-ofp7tupv	27	7	present	present	JJ
cord-256187-ofp7tupv	27	8	available	available	JJ
cord-256187-ofp7tupv	27	9	to	to	TO
cord-256187-ofp7tupv	27	10	combat	combat	VB
cord-256187-ofp7tupv	27	11	EBOV	EBOV	NNP
cord-256187-ofp7tupv	27	12	infection	infection	NN
cord-256187-ofp7tupv	27	13	,	,	,
cord-256187-ofp7tupv	27	14	making	make	VBG
cord-256187-ofp7tupv	27	15	the	the	DT
cord-256187-ofp7tupv	27	16	virus	virus	NN
cord-256187-ofp7tupv	27	17	a	a	DT
cord-256187-ofp7tupv	27	18	potential	potential	JJ
cord-256187-ofp7tupv	27	19	threat	threat	NN
cord-256187-ofp7tupv	27	20	to	to	IN
cord-256187-ofp7tupv	27	21	public	public	JJ
cord-256187-ofp7tupv	27	22	health	health	NN
cord-256187-ofp7tupv	27	23	.	.	.
cord-256187-ofp7tupv	28	1	To	to	TO
cord-256187-ofp7tupv	28	2	devise	devise	VB
cord-256187-ofp7tupv	28	3	antiviral	antiviral	JJ
cord-256187-ofp7tupv	28	4	strategies	strategy	NNS
cord-256187-ofp7tupv	28	5	,	,	,
cord-256187-ofp7tupv	28	6	it	-PRON-	PRP
cord-256187-ofp7tupv	28	7	is	be	VBZ
cord-256187-ofp7tupv	28	8	important	important	JJ
cord-256187-ofp7tupv	28	9	to	to	TO
cord-256187-ofp7tupv	28	10	understand	understand	VB
cord-256187-ofp7tupv	28	11	which	which	WDT
cord-256187-ofp7tupv	28	12	components	component	NNS
cord-256187-ofp7tupv	28	13	of	of	IN
cord-256187-ofp7tupv	28	14	the	the	DT
cord-256187-ofp7tupv	28	15	immune	immune	JJ
cord-256187-ofp7tupv	28	16	system	system	NN
cord-256187-ofp7tupv	28	17	could	could	MD
cord-256187-ofp7tupv	28	18	be	be	VB
cord-256187-ofp7tupv	28	19	effective	effective	JJ
cord-256187-ofp7tupv	28	20	against	against	IN
cord-256187-ofp7tupv	28	21	EBOV	EBOV	NNP
cord-256187-ofp7tupv	28	22	infection	infection	NN
cord-256187-ofp7tupv	28	23	.	.	.
cord-256187-ofp7tupv	29	1	The	the	DT
cord-256187-ofp7tupv	29	2	interferon	interferon	NN
cord-256187-ofp7tupv	29	3	(	(	-LRB-
cord-256187-ofp7tupv	29	4	IFN	IFN	NNP
cord-256187-ofp7tupv	29	5	)	)	-RRB-
cord-256187-ofp7tupv	29	6	system	system	NN
cord-256187-ofp7tupv	29	7	constitutes	constitute	VBZ
cord-256187-ofp7tupv	29	8	a	a	DT
cord-256187-ofp7tupv	29	9	key	key	JJ
cord-256187-ofp7tupv	29	10	innate	innate	JJ
cord-256187-ofp7tupv	29	11	defence	defence	NN
cord-256187-ofp7tupv	29	12	against	against	IN
cord-256187-ofp7tupv	29	13	viral	viral	JJ
cord-256187-ofp7tupv	29	14	infections	infection	NNS
cord-256187-ofp7tupv	29	15	and	and	CC
cord-256187-ofp7tupv	29	16	prevents	prevent	VBZ
cord-256187-ofp7tupv	29	17	development	development	NN
cord-256187-ofp7tupv	29	18	of	of	IN
cord-256187-ofp7tupv	29	19	lethal	lethal	JJ
cord-256187-ofp7tupv	29	20	disease	disease	NN
cord-256187-ofp7tupv	29	21	in	in	IN
cord-256187-ofp7tupv	29	22	mice	mouse	NNS
cord-256187-ofp7tupv	29	23	infected	infect	VBN
cord-256187-ofp7tupv	29	24	with	with	IN
cord-256187-ofp7tupv	29	25	EBOV	EBOV	NNP
cord-256187-ofp7tupv	29	26	strains	strain	NNS
cord-256187-ofp7tupv	29	27	not	not	RB
cord-256187-ofp7tupv	29	28	adapted	adapt	VBN
cord-256187-ofp7tupv	29	29	to	to	IN
cord-256187-ofp7tupv	29	30	this	this	DT
cord-256187-ofp7tupv	29	31	host	host	NN
cord-256187-ofp7tupv	29	32	.	.	.
cord-256187-ofp7tupv	30	1	Recent	recent	JJ
cord-256187-ofp7tupv	30	2	research	research	NN
cord-256187-ofp7tupv	30	3	revealed	reveal	VBD
cord-256187-ofp7tupv	30	4	that	that	IN
cord-256187-ofp7tupv	30	5	expression	expression	NN
cord-256187-ofp7tupv	30	6	of	of	IN
cord-256187-ofp7tupv	30	7	the	the	DT
cord-256187-ofp7tupv	30	8	host	host	NN
cord-256187-ofp7tupv	30	9	cell	cell	NN
cord-256187-ofp7tupv	30	10	IFN	IFN	NNP
cord-256187-ofp7tupv	30	11	-	-	HYPH
cord-256187-ofp7tupv	30	12	inducible	inducible	JJ
cord-256187-ofp7tupv	30	13	transmembrane	transmembrane	NN
cord-256187-ofp7tupv	30	14	proteins	protein	NNS
cord-256187-ofp7tupv	30	15	1	1	CD
cord-256187-ofp7tupv	30	16	-	-	SYM
cord-256187-ofp7tupv	30	17	3	3	CD
cord-256187-ofp7tupv	30	18	(	(	-LRB-
cord-256187-ofp7tupv	30	19	IFITM1	IFITM1	NNP
cord-256187-ofp7tupv	30	20	-	-	HYPH
cord-256187-ofp7tupv	30	21	3	3	CD
cord-256187-ofp7tupv	30	22	)	)	-RRB-
cord-256187-ofp7tupv	30	23	and	and	CC
cord-256187-ofp7tupv	30	24	tetherin	tetherin	NNP
cord-256187-ofp7tupv	30	25	is	be	VBZ
cord-256187-ofp7tupv	30	26	induced	induce	VBN
cord-256187-ofp7tupv	30	27	by	by	IN
cord-256187-ofp7tupv	30	28	IFN	IFN	NNP
cord-256187-ofp7tupv	30	29	and	and	CC
cord-256187-ofp7tupv	30	30	restricts	restrict	VBZ
cord-256187-ofp7tupv	30	31	EBOV	EBOV	NNP
cord-256187-ofp7tupv	30	32	infection	infection	NN
cord-256187-ofp7tupv	30	33	,	,	,
cord-256187-ofp7tupv	30	34	at	at	IN
cord-256187-ofp7tupv	30	35	least	least	JJS
cord-256187-ofp7tupv	30	36	in	in	IN
cord-256187-ofp7tupv	30	37	cell	cell	NN
cord-256187-ofp7tupv	30	38	culture	culture	NN
cord-256187-ofp7tupv	30	39	model	model	NN
cord-256187-ofp7tupv	30	40	systems	system	NNS
cord-256187-ofp7tupv	30	41	.	.	.
cord-256187-ofp7tupv	31	1	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	31	2	,	,	,
cord-256187-ofp7tupv	31	3	tetherin	tetherin	NNP
cord-256187-ofp7tupv	31	4	and	and	CC
cord-256187-ofp7tupv	31	5	other	other	JJ
cord-256187-ofp7tupv	31	6	effector	effector	NN
cord-256187-ofp7tupv	31	7	molecules	molecule	NNS
cord-256187-ofp7tupv	31	8	of	of	IN
cord-256187-ofp7tupv	31	9	the	the	DT
cord-256187-ofp7tupv	31	10	IFN	IFN	NNP
cord-256187-ofp7tupv	31	11	system	system	NN
cord-256187-ofp7tupv	31	12	could	could	MD
cord-256187-ofp7tupv	31	13	thus	thus	RB
cord-256187-ofp7tupv	31	14	pose	pose	VB
cord-256187-ofp7tupv	31	15	a	a	DT
cord-256187-ofp7tupv	31	16	potent	potent	JJ
cord-256187-ofp7tupv	31	17	barrier	barrier	NN
cord-256187-ofp7tupv	31	18	against	against	IN
cord-256187-ofp7tupv	31	19	EBOV	EBOV	NNP
cord-256187-ofp7tupv	31	20	spread	spread	VBD
cord-256187-ofp7tupv	31	21	in	in	IN
cord-256187-ofp7tupv	31	22	humans	human	NNS
cord-256187-ofp7tupv	31	23	.	.	.
cord-256187-ofp7tupv	32	1	However	however	RB
cord-256187-ofp7tupv	32	2	,	,	,
cord-256187-ofp7tupv	32	3	EBOV	EBOV	NNP
cord-256187-ofp7tupv	32	4	interferes	interfere	VBZ
cord-256187-ofp7tupv	32	5	with	with	IN
cord-256187-ofp7tupv	32	6	signalling	signal	VBG
cord-256187-ofp7tupv	32	7	events	event	NNS
cord-256187-ofp7tupv	32	8	required	require	VBN
cord-256187-ofp7tupv	32	9	for	for	IN
cord-256187-ofp7tupv	32	10	human	human	JJ
cord-256187-ofp7tupv	32	11	cells	cell	NNS
cord-256187-ofp7tupv	32	12	to	to	TO
cord-256187-ofp7tupv	32	13	express	express	VB
cord-256187-ofp7tupv	32	14	these	these	DT
cord-256187-ofp7tupv	32	15	proteins	protein	NNS
cord-256187-ofp7tupv	32	16	.	.	.
cord-256187-ofp7tupv	33	1	Here	here	RB
cord-256187-ofp7tupv	33	2	,	,	,
cord-256187-ofp7tupv	33	3	we	-PRON-	PRP
cord-256187-ofp7tupv	33	4	will	will	MD
cord-256187-ofp7tupv	33	5	review	review	VB
cord-256187-ofp7tupv	33	6	the	the	DT
cord-256187-ofp7tupv	33	7	strategies	strategy	NNS
cord-256187-ofp7tupv	33	8	employed	employ	VBN
cord-256187-ofp7tupv	33	9	by	by	IN
cord-256187-ofp7tupv	33	10	EBOV	EBOV	NNP
cord-256187-ofp7tupv	33	11	to	to	TO
cord-256187-ofp7tupv	33	12	fight	fight	VB
cord-256187-ofp7tupv	33	13	the	the	DT
cord-256187-ofp7tupv	33	14	IFN	IFN	NNP
cord-256187-ofp7tupv	33	15	system	system	NN
cord-256187-ofp7tupv	33	16	,	,	,
cord-256187-ofp7tupv	33	17	and	and	CC
cord-256187-ofp7tupv	33	18	we	-PRON-	PRP
cord-256187-ofp7tupv	33	19	will	will	MD
cord-256187-ofp7tupv	33	20	discuss	discuss	VB
cord-256187-ofp7tupv	33	21	how	how	WRB
cord-256187-ofp7tupv	33	22	IFITM	IFITM	NNP
cord-256187-ofp7tupv	33	23	proteins	protein	NNS
cord-256187-ofp7tupv	33	24	and	and	CC
cord-256187-ofp7tupv	33	25	tetherin	tetherin	NN
cord-256187-ofp7tupv	33	26	inhibit	inhibit	VBP
cord-256187-ofp7tupv	33	27	EBOV	EBOV	NNP
cord-256187-ofp7tupv	33	28	infection	infection	NN
cord-256187-ofp7tupv	33	29	.	.	.
cord-256187-ofp7tupv	34	1	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	34	2	,	,	,
cord-256187-ofp7tupv	34	3	SEBOV	SEBOV	NNP
cord-256187-ofp7tupv	34	4	,	,	,
cord-256187-ofp7tupv	34	5	CIEBOV	CIEBOV	NNP
cord-256187-ofp7tupv	34	6	and	and	CC
cord-256187-ofp7tupv	34	7	BEBOV	BEBOV	NNP
cord-256187-ofp7tupv	34	8	have	have	VBP
cord-256187-ofp7tupv	34	9	been	be	VBN
cord-256187-ofp7tupv	34	10	recorded	record	VBN
cord-256187-ofp7tupv	34	11	in	in	IN
cord-256187-ofp7tupv	34	12	Africa	Africa	NNP
cord-256187-ofp7tupv	34	13	and	and	CC
cord-256187-ofp7tupv	34	14	were	be	VBD
cord-256187-ofp7tupv	34	15	associated	associate	VBN
cord-256187-ofp7tupv	34	16	with	with	IN
cord-256187-ofp7tupv	34	17	case	case	NN
cord-256187-ofp7tupv	34	18	-	-	HYPH
cord-256187-ofp7tupv	34	19	fatality	fatality	NN
cord-256187-ofp7tupv	34	20	rates	rate	NNS
cord-256187-ofp7tupv	34	21	of	of	IN
cord-256187-ofp7tupv	34	22	up	up	IN
cord-256187-ofp7tupv	34	23	to	to	TO
cord-256187-ofp7tupv	34	24	90	90	CD
cord-256187-ofp7tupv	34	25	%	%	NN
cord-256187-ofp7tupv	34	26	in	in	IN
cord-256187-ofp7tupv	34	27	larger	large	JJR
cord-256187-ofp7tupv	34	28	outbreaks	outbreak	NNS
cord-256187-ofp7tupv	34	29	.	.	.
cord-256187-ofp7tupv	35	1	REBOV	REBOV	NNP
cord-256187-ofp7tupv	35	2	has	have	VBZ
cord-256187-ofp7tupv	35	3	been	be	VBN
cord-256187-ofp7tupv	35	4	detected	detect	VBN
cord-256187-ofp7tupv	35	5	in	in	IN
cord-256187-ofp7tupv	35	6	swine	swine	NN
cord-256187-ofp7tupv	35	7	in	in	IN
cord-256187-ofp7tupv	35	8	the	the	DT
cord-256187-ofp7tupv	35	9	Philippines	Philippines	NNPS
cord-256187-ofp7tupv	35	10	and	and	CC
cord-256187-ofp7tupv	35	11	is	be	VBZ
cord-256187-ofp7tupv	35	12	believed	believe	VBN
cord-256187-ofp7tupv	35	13	to	to	TO
cord-256187-ofp7tupv	35	14	be	be	VB
cord-256187-ofp7tupv	35	15	apathogenic	apathogenic	JJ
cord-256187-ofp7tupv	35	16	for	for	IN
cord-256187-ofp7tupv	35	17	humans	human	NNS
cord-256187-ofp7tupv	35	18	with	with	IN
cord-256187-ofp7tupv	35	19	an	an	DT
cord-256187-ofp7tupv	35	20	intact	intact	JJ
cord-256187-ofp7tupv	35	21	immune	immune	JJ
cord-256187-ofp7tupv	35	22	system	system	NN
cord-256187-ofp7tupv	35	23	(	(	-LRB-
cord-256187-ofp7tupv	35	24	Barrette	Barrette	NNP
cord-256187-ofp7tupv	35	25	et	et	NNP
cord-256187-ofp7tupv	35	26	al	al	NNP
cord-256187-ofp7tupv	35	27	.	.	NNP
cord-256187-ofp7tupv	35	28	,	,	,
cord-256187-ofp7tupv	35	29	2009	2009	CD
cord-256187-ofp7tupv	35	30	;	;	:
cord-256187-ofp7tupv	35	31	Hartman	Hartman	NNP
cord-256187-ofp7tupv	35	32	et	et	NNP
cord-256187-ofp7tupv	35	33	al	al	NNP
cord-256187-ofp7tupv	35	34	.	.	NNP
cord-256187-ofp7tupv	35	35	,	,	,
cord-256187-ofp7tupv	35	36	2010	2010	CD
cord-256187-ofp7tupv	35	37	)	)	-RRB-
cord-256187-ofp7tupv	35	38	.	.	.
cord-256187-ofp7tupv	36	1	The	the	DT
cord-256187-ofp7tupv	36	2	determinants	determinant	NNS
cord-256187-ofp7tupv	36	3	accounting	account	VBG
cord-256187-ofp7tupv	36	4	for	for	IN
cord-256187-ofp7tupv	36	5	the	the	DT
cord-256187-ofp7tupv	36	6	differential	differential	JJ
cord-256187-ofp7tupv	36	7	pathogenicity	pathogenicity	NN
cord-256187-ofp7tupv	36	8	of	of	IN
cord-256187-ofp7tupv	36	9	the	the	DT
cord-256187-ofp7tupv	36	10	different	different	JJ
cord-256187-ofp7tupv	36	11	EBOV	EBOV	NNP
cord-256187-ofp7tupv	36	12	species	specie	NNS
cord-256187-ofp7tupv	36	13	are	be	VBP
cord-256187-ofp7tupv	36	14	poorly	poorly	RB
cord-256187-ofp7tupv	36	15	understood	understand	VBN
cord-256187-ofp7tupv	36	16	.	.	.
cord-256187-ofp7tupv	37	1	The	the	DT
cord-256187-ofp7tupv	37	2	EBOV	EBOV	NNP
cord-256187-ofp7tupv	37	3	genome	genome	NN
cord-256187-ofp7tupv	37	4	encodes	encode	VBZ
cord-256187-ofp7tupv	37	5	three	three	CD
cord-256187-ofp7tupv	37	6	non	non	JJ
cord-256187-ofp7tupv	37	7	-	-	JJ
cord-256187-ofp7tupv	37	8	structural	structural	JJ
cord-256187-ofp7tupv	37	9	(	(	-LRB-
cord-256187-ofp7tupv	37	10	sGP	sgp	XX
cord-256187-ofp7tupv	37	11	,	,	,
cord-256187-ofp7tupv	37	12	ssGP	ssGP	NNP
cord-256187-ofp7tupv	37	13	,	,	,
cord-256187-ofp7tupv	37	14	D	d	NN
cord-256187-ofp7tupv	37	15	-	-	HYPH
cord-256187-ofp7tupv	37	16	peptide	peptide	JJ
cord-256187-ofp7tupv	37	17	,	,	,
cord-256187-ofp7tupv	37	18	as	as	IN
cord-256187-ofp7tupv	37	19	discussed	discuss	VBN
cord-256187-ofp7tupv	37	20	later	later	RB
cord-256187-ofp7tupv	37	21	)	)	-RRB-
cord-256187-ofp7tupv	37	22	and	and	CC
cord-256187-ofp7tupv	37	23	seven	seven	CD
cord-256187-ofp7tupv	37	24	structural	structural	JJ
cord-256187-ofp7tupv	37	25	proteins	protein	NNS
cord-256187-ofp7tupv	38	1	(	(	-LRB-
cord-256187-ofp7tupv	38	2	Fig	Fig	NNP
cord-256187-ofp7tupv	38	3	.	.	NNP
cord-256187-ofp7tupv	38	4	1	1	CD
cord-256187-ofp7tupv	38	5	)	)	-RRB-
cord-256187-ofp7tupv	38	6	.	.	.
cord-256187-ofp7tupv	39	1	The	the	DT
cord-256187-ofp7tupv	39	2	N	N	NNP
cord-256187-ofp7tupv	39	3	protein	protein	NN
cord-256187-ofp7tupv	39	4	(	(	-LRB-
cord-256187-ofp7tupv	39	5	NP	NP	NNP
cord-256187-ofp7tupv	39	6	)	)	-RRB-
cord-256187-ofp7tupv	39	7	,	,	,
cord-256187-ofp7tupv	39	8	the	the	DT
cord-256187-ofp7tupv	39	9	L	L	NNP
cord-256187-ofp7tupv	39	10	protein	protein	NN
cord-256187-ofp7tupv	39	11	,	,	,
cord-256187-ofp7tupv	39	12	viral	viral	JJ
cord-256187-ofp7tupv	39	13	protein	protein	NN
cord-256187-ofp7tupv	39	14	30	30	CD
cord-256187-ofp7tupv	39	15	(	(	-LRB-
cord-256187-ofp7tupv	39	16	VP30	VP30	NNP
cord-256187-ofp7tupv	39	17	)	)	-RRB-
cord-256187-ofp7tupv	39	18	and	and	CC
cord-256187-ofp7tupv	39	19	VP35	VP35	NNP
cord-256187-ofp7tupv	39	20	are	be	VBP
cord-256187-ofp7tupv	39	21	associated	associate	VBN
cord-256187-ofp7tupv	39	22	with	with	IN
cord-256187-ofp7tupv	39	23	the	the	DT
cord-256187-ofp7tupv	39	24	viral	viral	JJ
cord-256187-ofp7tupv	39	25	RNA	RNA	NNP
cord-256187-ofp7tupv	39	26	,	,	,
cord-256187-ofp7tupv	39	27	forming	form	VBG
cord-256187-ofp7tupv	39	28	a	a	DT
cord-256187-ofp7tupv	39	29	ribonucleoprotein	ribonucleoprotein	NN
cord-256187-ofp7tupv	39	30	(	(	-LRB-
cord-256187-ofp7tupv	39	31	RNP	RNP	NNP
cord-256187-ofp7tupv	39	32	)	)	-RRB-
cord-256187-ofp7tupv	39	33	complex	complex	NN
cord-256187-ofp7tupv	39	34	.	.	.
cord-256187-ofp7tupv	40	1	The	the	DT
cord-256187-ofp7tupv	40	2	L	L	NNP
cord-256187-ofp7tupv	40	3	protein	protein	NN
cord-256187-ofp7tupv	40	4	has	have	VBZ
cord-256187-ofp7tupv	40	5	a	a	DT
cord-256187-ofp7tupv	40	6	polymerase	polymerase	NN
cord-256187-ofp7tupv	40	7	function	function	NN
cord-256187-ofp7tupv	40	8	and	and	CC
cord-256187-ofp7tupv	40	9	is	be	VBZ
cord-256187-ofp7tupv	40	10	essential	essential	JJ
cord-256187-ofp7tupv	40	11	for	for	IN
cord-256187-ofp7tupv	40	12	genome	genome	NN
cord-256187-ofp7tupv	40	13	replication	replication	NN
cord-256187-ofp7tupv	40	14	and	and	CC
cord-256187-ofp7tupv	40	15	transcription	transcription	NN
cord-256187-ofp7tupv	40	16	,	,	,
cord-256187-ofp7tupv	40	17	and	and	CC
cord-256187-ofp7tupv	40	18	these	these	DT
cord-256187-ofp7tupv	40	19	processes	process	NNS
cord-256187-ofp7tupv	40	20	are	be	VBP
cord-256187-ofp7tupv	40	21	regulated	regulate	VBN
cord-256187-ofp7tupv	40	22	by	by	IN
cord-256187-ofp7tupv	40	23	VP30	VP30	NNP
cord-256187-ofp7tupv	40	24	and	and	CC
cord-256187-ofp7tupv	40	25	VP35	VP35	NNP
cord-256187-ofp7tupv	40	26	(	(	-LRB-
cord-256187-ofp7tupv	40	27	Dolnik	Dolnik	NNP
cord-256187-ofp7tupv	40	28	et	et	FW
cord-256187-ofp7tupv	40	29	al	al	NNP
cord-256187-ofp7tupv	40	30	.	.	NNP
cord-256187-ofp7tupv	40	31	,	,	,
cord-256187-ofp7tupv	40	32	2008	2008	CD
cord-256187-ofp7tupv	40	33	)	)	-RRB-
cord-256187-ofp7tupv	40	34	.	.	.
cord-256187-ofp7tupv	41	1	The	the	DT
cord-256187-ofp7tupv	41	2	minor	minor	JJ
cord-256187-ofp7tupv	41	3	matrix	matrix	NN
cord-256187-ofp7tupv	41	4	protein	protein	NN
cord-256187-ofp7tupv	41	5	,	,	,
cord-256187-ofp7tupv	41	6	VP24	VP24	NNP
cord-256187-ofp7tupv	41	7	,	,	,
cord-256187-ofp7tupv	41	8	contributes	contribute	VBZ
cord-256187-ofp7tupv	41	9	to	to	IN
cord-256187-ofp7tupv	41	10	nucleocapsid	nucleocapsid	NNP
cord-256187-ofp7tupv	41	11	formation	formation	NN
cord-256187-ofp7tupv	41	12	,	,	,
cord-256187-ofp7tupv	41	13	while	while	IN
cord-256187-ofp7tupv	41	14	the	the	DT
cord-256187-ofp7tupv	41	15	major	major	JJ
cord-256187-ofp7tupv	41	16	matrix	matrix	NN
cord-256187-ofp7tupv	41	17	protein	protein	NN
cord-256187-ofp7tupv	41	18	,	,	,
cord-256187-ofp7tupv	41	19	VP40	VP40	NNP
cord-256187-ofp7tupv	41	20	,	,	,
cord-256187-ofp7tupv	41	21	facilitates	facilitate	VBZ
cord-256187-ofp7tupv	41	22	budding	budding	NN
cord-256187-ofp7tupv	41	23	of	of	IN
cord-256187-ofp7tupv	41	24	progeny	progeny	NN
cord-256187-ofp7tupv	41	25	particles	particle	NNS
cord-256187-ofp7tupv	41	26	from	from	IN
cord-256187-ofp7tupv	41	27	infected	infected	JJ
cord-256187-ofp7tupv	41	28	cells	cell	NNS
cord-256187-ofp7tupv	41	29	(	(	-LRB-
cord-256187-ofp7tupv	42	1	Huang	Huang	NNP
cord-256187-ofp7tupv	42	2	et	et	NNP
cord-256187-ofp7tupv	42	3	al	al	NNP
cord-256187-ofp7tupv	42	4	.	.	.
cord-256187-ofp7tupv	43	1	,	,	,
cord-256187-ofp7tupv	43	2	2002	2002	CD
cord-256187-ofp7tupv	43	3	;	;	:
cord-256187-ofp7tupv	43	4	Hartlieb	Hartlieb	NNP
cord-256187-ofp7tupv	43	5	and	and	CC
cord-256187-ofp7tupv	43	6	Weissenhorn	Weissenhorn	NNP
cord-256187-ofp7tupv	43	7	,	,	,
cord-256187-ofp7tupv	43	8	2006	2006	CD
cord-256187-ofp7tupv	43	9	;	;	:
cord-256187-ofp7tupv	43	10	Dolnik	Dolnik	NNP
cord-256187-ofp7tupv	43	11	et	et	FW
cord-256187-ofp7tupv	43	12	al	al	NNP
cord-256187-ofp7tupv	43	13	.	.	NNP
cord-256187-ofp7tupv	43	14	,	,	,
cord-256187-ofp7tupv	43	15	2008	2008	CD
cord-256187-ofp7tupv	43	16	)	)	-RRB-
cord-256187-ofp7tupv	44	1	(	(	-LRB-
cord-256187-ofp7tupv	44	2	Fig	Fig	NNP
cord-256187-ofp7tupv	44	3	.	.	NNP
cord-256187-ofp7tupv	44	4	1	1	CD
cord-256187-ofp7tupv	44	5	)	)	-RRB-
cord-256187-ofp7tupv	44	6	.	.	.
cord-256187-ofp7tupv	45	1	The	the	DT
cord-256187-ofp7tupv	45	2	structural	structural	JJ
cord-256187-ofp7tupv	45	3	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	45	4	,	,	,
cord-256187-ofp7tupv	45	5	GP	GP	NNP
cord-256187-ofp7tupv	45	6	1,2	1,2	CD
cord-256187-ofp7tupv	45	7	,	,	,
cord-256187-ofp7tupv	45	8	mediates	mediate	VBZ
cord-256187-ofp7tupv	45	9	binding	bind	VBG
cord-256187-ofp7tupv	45	10	and	and	CC
cord-256187-ofp7tupv	45	11	infectious	infectious	JJ
cord-256187-ofp7tupv	45	12	entry	entry	NN
cord-256187-ofp7tupv	45	13	into	into	IN
cord-256187-ofp7tupv	45	14	host	host	NN
cord-256187-ofp7tupv	45	15	cells	cell	NNS
cord-256187-ofp7tupv	45	16	(	(	-LRB-
cord-256187-ofp7tupv	45	17	Kawaoka	Kawaoka	NNP
cord-256187-ofp7tupv	45	18	,	,	,
cord-256187-ofp7tupv	45	19	2005	2005	CD
cord-256187-ofp7tupv	45	20	)	)	-RRB-
cord-256187-ofp7tupv	45	21	.	.	.
cord-256187-ofp7tupv	46	1	Innate	innate	JJ
cord-256187-ofp7tupv	46	2	defences	defence	NNS
cord-256187-ofp7tupv	46	3	of	of	IN
cord-256187-ofp7tupv	46	4	the	the	DT
cord-256187-ofp7tupv	46	5	host	host	NN
cord-256187-ofp7tupv	46	6	are	be	VBP
cord-256187-ofp7tupv	46	7	crucial	crucial	JJ
cord-256187-ofp7tupv	46	8	to	to	TO
cord-256187-ofp7tupv	46	9	successfully	successfully	RB
cord-256187-ofp7tupv	46	10	fight	fight	VB
cord-256187-ofp7tupv	46	11	EBOV	EBOV	NNP
cord-256187-ofp7tupv	46	12	and	and	CC
cord-256187-ofp7tupv	46	13	other	other	JJ
cord-256187-ofp7tupv	46	14	acute	acute	JJ
cord-256187-ofp7tupv	46	15	infections	infection	NNS
cord-256187-ofp7tupv	46	16	.	.	.
cord-256187-ofp7tupv	47	1	The	the	DT
cord-256187-ofp7tupv	47	2	interferon	interferon	NN
cord-256187-ofp7tupv	47	3	(	(	-LRB-
cord-256187-ofp7tupv	47	4	IFN	IFN	NNP
cord-256187-ofp7tupv	47	5	)	)	-RRB-
cord-256187-ofp7tupv	47	6	system	system	NN
cord-256187-ofp7tupv	47	7	is	be	VBZ
cord-256187-ofp7tupv	47	8	an	an	DT
cord-256187-ofp7tupv	47	9	integral	integral	JJ
cord-256187-ofp7tupv	47	10	part	part	NN
cord-256187-ofp7tupv	47	11	of	of	IN
cord-256187-ofp7tupv	47	12	the	the	DT
cord-256187-ofp7tupv	47	13	innate	innate	JJ
cord-256187-ofp7tupv	47	14	immunity	immunity	NN
cord-256187-ofp7tupv	47	15	against	against	IN
cord-256187-ofp7tupv	47	16	viral	viral	JJ
cord-256187-ofp7tupv	47	17	infections	infection	NNS
cord-256187-ofp7tupv	47	18	.	.	.
cord-256187-ofp7tupv	48	1	Sensor	sensor	NN
cord-256187-ofp7tupv	48	2	molecules	molecule	NNS
cord-256187-ofp7tupv	48	3	of	of	IN
cord-256187-ofp7tupv	48	4	the	the	DT
cord-256187-ofp7tupv	48	5	IFN	IFN	NNP
cord-256187-ofp7tupv	48	6	system	system	NN
cord-256187-ofp7tupv	48	7	recognize	recognize	VBP
cord-256187-ofp7tupv	48	8	viral	viral	JJ
cord-256187-ofp7tupv	48	9	components	component	NNS
cord-256187-ofp7tupv	48	10	and	and	CC
cord-256187-ofp7tupv	48	11	induce	induce	VB
cord-256187-ofp7tupv	48	12	signalling	signal	VBG
cord-256187-ofp7tupv	48	13	that	that	WDT
cord-256187-ofp7tupv	48	14	triggers	trigger	VBZ
cord-256187-ofp7tupv	48	15	expression	expression	NN
cord-256187-ofp7tupv	48	16	of	of	IN
cord-256187-ofp7tupv	48	17	IFNs	ifn	NNS
cord-256187-ofp7tupv	48	18	(	(	-LRB-
cord-256187-ofp7tupv	48	19	Baum	Baum	NNP
cord-256187-ofp7tupv	48	20	and	and	CC
cord-256187-ofp7tupv	48	21	García	García	NNP
cord-256187-ofp7tupv	48	22	-	-	HYPH
cord-256187-ofp7tupv	48	23	Sastre	Sastre	NNP
cord-256187-ofp7tupv	48	24	,	,	,
cord-256187-ofp7tupv	48	25	2011	2011	CD
cord-256187-ofp7tupv	48	26	)	)	-RRB-
cord-256187-ofp7tupv	48	27	.	.	.
cord-256187-ofp7tupv	49	1	Subsequent	subsequent	JJ
cord-256187-ofp7tupv	49	2	binding	binding	NN
cord-256187-ofp7tupv	49	3	of	of	IN
cord-256187-ofp7tupv	49	4	IFN	IFN	NNP
cord-256187-ofp7tupv	49	5	to	to	IN
cord-256187-ofp7tupv	49	6	IFN	IFN	NNP
cord-256187-ofp7tupv	49	7	receptors	receptor	NNS
cord-256187-ofp7tupv	49	8	on	on	IN
cord-256187-ofp7tupv	49	9	uninfected	uninfected	JJ
cord-256187-ofp7tupv	49	10	cells	cell	NNS
cord-256187-ofp7tupv	49	11	activates	activate	VBZ
cord-256187-ofp7tupv	49	12	signal	signal	NN
cord-256187-ofp7tupv	49	13	transducer	transducer	NN
cord-256187-ofp7tupv	49	14	and	and	CC
cord-256187-ofp7tupv	49	15	activator	activator	NN
cord-256187-ofp7tupv	49	16	of	of	IN
cord-256187-ofp7tupv	49	17	transcription	transcription	NN
cord-256187-ofp7tupv	49	18	(	(	-LRB-
cord-256187-ofp7tupv	49	19	STAT)-dependent	stat)-dependent	NN
cord-256187-ofp7tupv	49	20	signalling	signal	VBG
cord-256187-ofp7tupv	49	21	,	,	,
cord-256187-ofp7tupv	49	22	which	which	WDT
cord-256187-ofp7tupv	49	23	commandeers	commandeer	VBZ
cord-256187-ofp7tupv	49	24	the	the	DT
cord-256187-ofp7tupv	49	25	cell	cell	NN
cord-256187-ofp7tupv	49	26	to	to	TO
cord-256187-ofp7tupv	49	27	express	express	VB
cord-256187-ofp7tupv	49	28	IFN	IFN	NNP
cord-256187-ofp7tupv	49	29	-	-	HYPH
cord-256187-ofp7tupv	49	30	stimulated	stimulate	VBN
cord-256187-ofp7tupv	49	31	genes	gene	NNS
cord-256187-ofp7tupv	49	32	(	(	-LRB-
cord-256187-ofp7tupv	49	33	ISGs	ISGs	NNP
cord-256187-ofp7tupv	49	34	)	)	-RRB-
cord-256187-ofp7tupv	49	35	,	,	,
cord-256187-ofp7tupv	49	36	which	which	WDT
cord-256187-ofp7tupv	49	37	can	can	MD
cord-256187-ofp7tupv	49	38	function	function	VB
cord-256187-ofp7tupv	49	39	as	as	IN
cord-256187-ofp7tupv	49	40	antiviral	antiviral	JJ
cord-256187-ofp7tupv	49	41	effectors	effector	NNS
cord-256187-ofp7tupv	49	42	molecules	molecule	NNS
cord-256187-ofp7tupv	49	43	(	(	-LRB-
cord-256187-ofp7tupv	49	44	Schindler	Schindler	NNP
cord-256187-ofp7tupv	49	45	et	et	NNP
cord-256187-ofp7tupv	49	46	al	al	NNP
cord-256187-ofp7tupv	49	47	.	.	NNP
cord-256187-ofp7tupv	49	48	,	,	,
cord-256187-ofp7tupv	49	49	2007	2007	CD
cord-256187-ofp7tupv	49	50	;	;	:
cord-256187-ofp7tupv	49	51	Sadler	Sadler	NNP
cord-256187-ofp7tupv	49	52	and	and	CC
cord-256187-ofp7tupv	49	53	Williams	Williams	NNP
cord-256187-ofp7tupv	49	54	,	,	,
cord-256187-ofp7tupv	49	55	2008	2008	CD
cord-256187-ofp7tupv	49	56	)	)	-RRB-
cord-256187-ofp7tupv	49	57	.	.	.
cord-256187-ofp7tupv	50	1	Ebola	Ebola	NNP
cord-256187-ofp7tupv	50	2	virus	virus	NN
cord-256187-ofp7tupv	50	3	strains	strain	VBZ
cord-256187-ofp7tupv	50	4	lethal	lethal	JJ
cord-256187-ofp7tupv	50	5	in	in	IN
cord-256187-ofp7tupv	50	6	humans	human	NNS
cord-256187-ofp7tupv	50	7	were	be	VBD
cord-256187-ofp7tupv	50	8	found	find	VBN
cord-256187-ofp7tupv	50	9	to	to	TO
cord-256187-ofp7tupv	50	10	be	be	VB
cord-256187-ofp7tupv	50	11	unable	unable	JJ
cord-256187-ofp7tupv	50	12	to	to	TO
cord-256187-ofp7tupv	50	13	produce	produce	VB
cord-256187-ofp7tupv	50	14	fatal	fatal	JJ
cord-256187-ofp7tupv	50	15	disease	disease	NN
cord-256187-ofp7tupv	50	16	in	in	IN
cord-256187-ofp7tupv	50	17	adult	adult	NN
cord-256187-ofp7tupv	50	18	mice	mouse	NNS
cord-256187-ofp7tupv	50	19	.	.	.
cord-256187-ofp7tupv	51	1	However	however	RB
cord-256187-ofp7tupv	51	2	,	,	,
cord-256187-ofp7tupv	51	3	when	when	WRB
cord-256187-ofp7tupv	51	4	essential	essential	JJ
cord-256187-ofp7tupv	51	5	components	component	NNS
cord-256187-ofp7tupv	51	6	of	of	IN
cord-256187-ofp7tupv	51	7	the	the	DT
cord-256187-ofp7tupv	51	8	IFN	IFN	NNP
cord-256187-ofp7tupv	51	9	system	system	NN
cord-256187-ofp7tupv	51	10	were	be	VBD
cord-256187-ofp7tupv	51	11	inactivated	inactivate	VBN
cord-256187-ofp7tupv	51	12	in	in	IN
cord-256187-ofp7tupv	51	13	mice	mouse	NNS
cord-256187-ofp7tupv	51	14	,	,	,
cord-256187-ofp7tupv	51	15	fatal	fatal	JJ
cord-256187-ofp7tupv	51	16	disease	disease	NN
cord-256187-ofp7tupv	51	17	was	be	VBD
cord-256187-ofp7tupv	51	18	observed	observe	VBN
cord-256187-ofp7tupv	51	19	(	(	-LRB-
cord-256187-ofp7tupv	51	20	Bray	Bray	NNP
cord-256187-ofp7tupv	51	21	,	,	,
cord-256187-ofp7tupv	51	22	2001	2001	CD
cord-256187-ofp7tupv	51	23	)	)	-RRB-
cord-256187-ofp7tupv	51	24	.	.	.
cord-256187-ofp7tupv	52	1	Similarly	similarly	RB
cord-256187-ofp7tupv	52	2	,	,	,
cord-256187-ofp7tupv	52	3	adaptation	adaptation	NN
cord-256187-ofp7tupv	52	4	of	of	IN
cord-256187-ofp7tupv	52	5	EBOV	EBOV	NNP
cord-256187-ofp7tupv	52	6	to	to	IN
cord-256187-ofp7tupv	52	7	efficient	efficient	JJ
cord-256187-ofp7tupv	52	8	replication	replication	NN
cord-256187-ofp7tupv	52	9	in	in	IN
cord-256187-ofp7tupv	52	10	adult	adult	NN
cord-256187-ofp7tupv	52	11	mice	mouse	NNS
cord-256187-ofp7tupv	53	1	(	(	-LRB-
cord-256187-ofp7tupv	53	2	Bray	Bray	NNP
cord-256187-ofp7tupv	53	3	et	et	NNP
cord-256187-ofp7tupv	53	4	al	al	NNP
cord-256187-ofp7tupv	53	5	.	.	NNP
cord-256187-ofp7tupv	53	6	,	,	,
cord-256187-ofp7tupv	53	7	1998	1998	CD
cord-256187-ofp7tupv	53	8	)	)	-RRB-
cord-256187-ofp7tupv	53	9	resulted	result	VBD
cord-256187-ofp7tupv	53	10	in	in	IN
cord-256187-ofp7tupv	53	11	the	the	DT
cord-256187-ofp7tupv	53	12	generation	generation	NN
cord-256187-ofp7tupv	53	13	of	of	IN
cord-256187-ofp7tupv	53	14	viruses	virus	NNS
cord-256187-ofp7tupv	53	15	with	with	IN
cord-256187-ofp7tupv	53	16	mutations	mutation	NNS
cord-256187-ofp7tupv	53	17	allowing	allow	VBG
cord-256187-ofp7tupv	53	18	efficient	efficient	JJ
cord-256187-ofp7tupv	53	19	interference	interference	NN
cord-256187-ofp7tupv	53	20	with	with	IN
cord-256187-ofp7tupv	53	21	components	component	NNS
cord-256187-ofp7tupv	53	22	of	of	IN
cord-256187-ofp7tupv	53	23	the	the	DT
cord-256187-ofp7tupv	53	24	murine	murine	JJ
cord-256187-ofp7tupv	53	25	IFN	IFN	NNP
cord-256187-ofp7tupv	53	26	system	system	NN
cord-256187-ofp7tupv	53	27	.	.	.
cord-256187-ofp7tupv	54	1	Thus	thus	RB
cord-256187-ofp7tupv	54	2	,	,	,
cord-256187-ofp7tupv	54	3	the	the	DT
cord-256187-ofp7tupv	54	4	IFN	IFN	NNP
cord-256187-ofp7tupv	54	5	system	system	NN
cord-256187-ofp7tupv	54	6	is	be	VBZ
cord-256187-ofp7tupv	54	7	generally	generally	RB
cord-256187-ofp7tupv	54	8	capable	capable	JJ
cord-256187-ofp7tupv	54	9	of	of	IN
cord-256187-ofp7tupv	54	10	restricting	restrict	VBG
cord-256187-ofp7tupv	54	11	filovirus	filovirus	NN
cord-256187-ofp7tupv	54	12	spread	spread	NN
cord-256187-ofp7tupv	54	13	and	and	CC
cord-256187-ofp7tupv	54	14	pathogenesis	pathogenesis	NN
cord-256187-ofp7tupv	54	15	.	.	.
cord-256187-ofp7tupv	55	1	However	however	RB
cord-256187-ofp7tupv	55	2	,	,	,
cord-256187-ofp7tupv	55	3	several	several	JJ
cord-256187-ofp7tupv	55	4	EBOV	EBOV	NNP
cord-256187-ofp7tupv	55	5	proteins	protein	NNS
cord-256187-ofp7tupv	55	6	are	be	VBP
cord-256187-ofp7tupv	55	7	well	well	RB
cord-256187-ofp7tupv	55	8	adapted	adapt	VBN
cord-256187-ofp7tupv	55	9	to	to	TO
cord-256187-ofp7tupv	55	10	block	block	VB
cord-256187-ofp7tupv	55	11	processes	process	NNS
cord-256187-ofp7tupv	55	12	essential	essential	JJ
cord-256187-ofp7tupv	55	13	for	for	IN
cord-256187-ofp7tupv	55	14	the	the	DT
cord-256187-ofp7tupv	55	15	establishment	establishment	NN
cord-256187-ofp7tupv	55	16	of	of	IN
cord-256187-ofp7tupv	55	17	a	a	DT
cord-256187-ofp7tupv	55	18	vigorous	vigorous	JJ
cord-256187-ofp7tupv	55	19	IFN	IFN	NNP
cord-256187-ofp7tupv	55	20	response	response	NN
cord-256187-ofp7tupv	55	21	in	in	IN
cord-256187-ofp7tupv	55	22	human	human	JJ
cord-256187-ofp7tupv	55	23	cells	cell	NNS
cord-256187-ofp7tupv	55	24	,	,	,
cord-256187-ofp7tupv	55	25	potentially	potentially	RB
cord-256187-ofp7tupv	55	26	explaining	explain	VBG
cord-256187-ofp7tupv	55	27	why	why	WRB
cord-256187-ofp7tupv	55	28	the	the	DT
cord-256187-ofp7tupv	55	29	IFN	IFN	NNP
cord-256187-ofp7tupv	55	30	system	system	NN
cord-256187-ofp7tupv	55	31	frequently	frequently	RB
cord-256187-ofp7tupv	55	32	fails	fail	VBZ
cord-256187-ofp7tupv	55	33	to	to	TO
cord-256187-ofp7tupv	55	34	protect	protect	VB
cord-256187-ofp7tupv	55	35	humans	human	NNS
cord-256187-ofp7tupv	55	36	from	from	IN
cord-256187-ofp7tupv	55	37	lethal	lethal	JJ
cord-256187-ofp7tupv	55	38	EBOV	EBOV	NNP
cord-256187-ofp7tupv	55	39	infection	infection	NN
cord-256187-ofp7tupv	55	40	,	,	,
cord-256187-ofp7tupv	55	41	as	as	IN
cord-256187-ofp7tupv	55	42	discussed	discuss	VBN
cord-256187-ofp7tupv	55	43	below	below	RB
cord-256187-ofp7tupv	55	44	.	.	.
cord-256187-ofp7tupv	56	1	The	the	DT
cord-256187-ofp7tupv	56	2	molecular	molecular	JJ
cord-256187-ofp7tupv	56	3	pathways	pathway	NNS
cord-256187-ofp7tupv	56	4	leading	lead	VBG
cord-256187-ofp7tupv	56	5	to	to	IN
cord-256187-ofp7tupv	56	6	expression	expression	NN
cord-256187-ofp7tupv	56	7	of	of	IN
cord-256187-ofp7tupv	56	8	IFNinduced	ifninduced	JJ
cord-256187-ofp7tupv	56	9	antiviral	antiviral	JJ
cord-256187-ofp7tupv	56	10	effector	effector	NN
cord-256187-ofp7tupv	56	11	molecules	molecule	NNS
cord-256187-ofp7tupv	56	12	,	,	,
cord-256187-ofp7tupv	56	13	and	and	CC
cord-256187-ofp7tupv	56	14	thus	thus	RB
cord-256187-ofp7tupv	56	15	to	to	IN
cord-256187-ofp7tupv	56	16	the	the	DT
cord-256187-ofp7tupv	56	17	transition	transition	NN
cord-256187-ofp7tupv	56	18	of	of	IN
cord-256187-ofp7tupv	56	19	cells	cell	NNS
cord-256187-ofp7tupv	56	20	into	into	IN
cord-256187-ofp7tupv	56	21	an	an	DT
cord-256187-ofp7tupv	56	22	antiviral	antiviral	JJ
cord-256187-ofp7tupv	56	23	state	state	NN
cord-256187-ofp7tupv	56	24	,	,	,
cord-256187-ofp7tupv	56	25	are	be	VBP
cord-256187-ofp7tupv	56	26	well	well	RB
cord-256187-ofp7tupv	56	27	characterized	characterize	VBN
cord-256187-ofp7tupv	56	28	(	(	-LRB-
cord-256187-ofp7tupv	56	29	Baum	Baum	NNP
cord-256187-ofp7tupv	56	30	and	and	CC
cord-256187-ofp7tupv	56	31	García	García	NNP
cord-256187-ofp7tupv	56	32	-	-	HYPH
cord-256187-ofp7tupv	56	33	Sastre	Sastre	NNP
cord-256187-ofp7tupv	56	34	,	,	,
cord-256187-ofp7tupv	56	35	2010	2010	CD
cord-256187-ofp7tupv	56	36	)	)	-RRB-
cord-256187-ofp7tupv	56	37	.	.	.
cord-256187-ofp7tupv	57	1	However	however	RB
cord-256187-ofp7tupv	57	2	,	,	,
cord-256187-ofp7tupv	57	3	the	the	DT
cord-256187-ofp7tupv	57	4	antiviral	antiviral	JJ
cord-256187-ofp7tupv	57	5	effector	effector	NN
cord-256187-ofp7tupv	57	6	molecules	molecule	NNS
cord-256187-ofp7tupv	57	7	induced	induce	VBN
cord-256187-ofp7tupv	57	8	by	by	IN
cord-256187-ofp7tupv	57	9	IFN	IFN	NNP
cord-256187-ofp7tupv	57	10	and	and	CC
cord-256187-ofp7tupv	57	11	the	the	DT
cord-256187-ofp7tupv	57	12	molecular	molecular	JJ
cord-256187-ofp7tupv	57	13	mechanisms	mechanism	NNS
cord-256187-ofp7tupv	57	14	underlying	underlie	VBG
cord-256187-ofp7tupv	57	15	their	-PRON-	PRP$
cord-256187-ofp7tupv	57	16	antiviral	antiviral	JJ
cord-256187-ofp7tupv	57	17	action	action	NN
cord-256187-ofp7tupv	57	18	are	be	VBP
cord-256187-ofp7tupv	57	19	incompletely	incompletely	RB
cord-256187-ofp7tupv	57	20	understood	understand	VBN
cord-256187-ofp7tupv	57	21	.	.	.
cord-256187-ofp7tupv	58	1	Recent	recent	JJ
cord-256187-ofp7tupv	58	2	,	,	,
cord-256187-ofp7tupv	58	3	groundbreaking	groundbreaking	NN
cord-256187-ofp7tupv	58	4	studies	study	NNS
cord-256187-ofp7tupv	58	5	attempted	attempt	VBD
cord-256187-ofp7tupv	58	6	to	to	TO
cord-256187-ofp7tupv	58	7	close	close	VB
cord-256187-ofp7tupv	58	8	this	this	DT
cord-256187-ofp7tupv	58	9	gap	gap	NN
cord-256187-ofp7tupv	59	1	(	(	-LRB-
cord-256187-ofp7tupv	59	2	Schoggins	Schoggins	NNP
cord-256187-ofp7tupv	59	3	et	et	NNP
cord-256187-ofp7tupv	59	4	al	al	NNP
cord-256187-ofp7tupv	59	5	.	.	NNP
cord-256187-ofp7tupv	59	6	,	,	,
cord-256187-ofp7tupv	59	7	2011	2011	CD
cord-256187-ofp7tupv	59	8	)	)	-RRB-
cord-256187-ofp7tupv	59	9	and	and	CC
cord-256187-ofp7tupv	59	10	identified	identify	VBD
cord-256187-ofp7tupv	59	11	novel	novel	JJ
cord-256187-ofp7tupv	59	12	ISGs	isg	NNS
cord-256187-ofp7tupv	59	13	,	,	,
cord-256187-ofp7tupv	59	14	among	among	IN
cord-256187-ofp7tupv	59	15	them	-PRON-	PRP
cord-256187-ofp7tupv	59	16	the	the	DT
cord-256187-ofp7tupv	59	17	tetherin	tetherin	NNS
cord-256187-ofp7tupv	59	18	and	and	CC
cord-256187-ofp7tupv	59	19	IFNinduced	IFNinduced	NNP
cord-256187-ofp7tupv	59	20	transmembrane	transmembrane	NN
cord-256187-ofp7tupv	59	21	proteins	protein	NNS
cord-256187-ofp7tupv	59	22	(	(	-LRB-
cord-256187-ofp7tupv	59	23	IFITMs	ifitms	NN
cord-256187-ofp7tupv	59	24	)	)	-RRB-
cord-256187-ofp7tupv	60	1	(	(	-LRB-
cord-256187-ofp7tupv	60	2	Neil	Neil	NNP
cord-256187-ofp7tupv	60	3	et	et	NNP
cord-256187-ofp7tupv	60	4	al	al	NNP
cord-256187-ofp7tupv	60	5	.	.	NNP
cord-256187-ofp7tupv	60	6	,	,	,
cord-256187-ofp7tupv	60	7	2008	2008	CD
cord-256187-ofp7tupv	60	8	;	;	:
cord-256187-ofp7tupv	60	9	Van	Van	NNP
cord-256187-ofp7tupv	60	10	Damme	Damme	NNP
cord-256187-ofp7tupv	60	11	et	et	FW
cord-256187-ofp7tupv	60	12	al	al	NNP
cord-256187-ofp7tupv	60	13	.	.	.
cord-256187-ofp7tupv	61	1	,	,	,
cord-256187-ofp7tupv	61	2	2008	2008	CD
cord-256187-ofp7tupv	61	3	;	;	:
cord-256187-ofp7tupv	61	4	Brass	Brass	NNP
cord-256187-ofp7tupv	61	5	et	et	NNP
cord-256187-ofp7tupv	61	6	al	al	NNP
cord-256187-ofp7tupv	61	7	.	.	NNP
cord-256187-ofp7tupv	61	8	,	,	,
cord-256187-ofp7tupv	61	9	2009	2009	CD
cord-256187-ofp7tupv	61	10	)	)	-RRB-
cord-256187-ofp7tupv	61	11	.	.	.
cord-256187-ofp7tupv	62	1	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	62	2	exhibits	exhibit	VBZ
cord-256187-ofp7tupv	62	3	an	an	DT
cord-256187-ofp7tupv	62	4	unusual	unusual	JJ
cord-256187-ofp7tupv	62	5	topology	topology	NN
cord-256187-ofp7tupv	62	6	and	and	CC
cord-256187-ofp7tupv	62	7	restricts	restrict	VBZ
cord-256187-ofp7tupv	62	8	release	release	NN
cord-256187-ofp7tupv	62	9	of	of	IN
cord-256187-ofp7tupv	62	10	several	several	JJ
cord-256187-ofp7tupv	62	11	enveloped	envelop	VBN
cord-256187-ofp7tupv	62	12	viruses	virus	NNS
cord-256187-ofp7tupv	62	13	and	and	CC
cord-256187-ofp7tupv	62	14	filovirus	filovirus	NN
cord-256187-ofp7tupv	62	15	-	-	HYPH
cord-256187-ofp7tupv	62	16	like	like	JJ
cord-256187-ofp7tupv	62	17	particles	particle	NNS
cord-256187-ofp7tupv	62	18	from	from	IN
cord-256187-ofp7tupv	62	19	infected	infected	JJ
cord-256187-ofp7tupv	62	20	cells	cell	NNS
cord-256187-ofp7tupv	62	21	,	,	,
cord-256187-ofp7tupv	62	22	while	while	IN
cord-256187-ofp7tupv	62	23	IFITM	IFITM	NNP
cord-256187-ofp7tupv	62	24	proteins	protein	NNS
cord-256187-ofp7tupv	62	25	inhibit	inhibit	VBP
cord-256187-ofp7tupv	62	26	infection	infection	NN
cord-256187-ofp7tupv	62	27	by	by	IN
cord-256187-ofp7tupv	62	28	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	62	29	and	and	CC
cord-256187-ofp7tupv	62	30	other	other	JJ
cord-256187-ofp7tupv	62	31	enveloped	envelop	VBN
cord-256187-ofp7tupv	62	32	viruses	virus	NNS
cord-256187-ofp7tupv	62	33	at	at	IN
cord-256187-ofp7tupv	62	34	the	the	DT
cord-256187-ofp7tupv	62	35	stage	stage	NN
cord-256187-ofp7tupv	62	36	of	of	IN
cord-256187-ofp7tupv	62	37	viral	viral	JJ
cord-256187-ofp7tupv	62	38	entry	entry	NN
cord-256187-ofp7tupv	62	39	,	,	,
cord-256187-ofp7tupv	62	40	as	as	IN
cord-256187-ofp7tupv	62	41	discussed	discuss	VBN
cord-256187-ofp7tupv	62	42	below	below	RB
cord-256187-ofp7tupv	62	43	.	.	.
cord-256187-ofp7tupv	63	1	In	in	IN
cord-256187-ofp7tupv	63	2	the	the	DT
cord-256187-ofp7tupv	63	3	present	present	JJ
cord-256187-ofp7tupv	63	4	review	review	NN
cord-256187-ofp7tupv	63	5	,	,	,
cord-256187-ofp7tupv	63	6	we	-PRON-	PRP
cord-256187-ofp7tupv	63	7	will	will	MD
cord-256187-ofp7tupv	63	8	summarize	summarize	VB
cord-256187-ofp7tupv	63	9	current	current	JJ
cord-256187-ofp7tupv	63	10	knowledge	knowledge	NN
cord-256187-ofp7tupv	63	11	on	on	IN
cord-256187-ofp7tupv	63	12	EBOV	EBOV	NNP
cord-256187-ofp7tupv	63	13	interference	interference	NN
cord-256187-ofp7tupv	63	14	with	with	IN
cord-256187-ofp7tupv	63	15	the	the	DT
cord-256187-ofp7tupv	63	16	IFN	IFN	NNP
cord-256187-ofp7tupv	63	17	system	system	NN
cord-256187-ofp7tupv	63	18	.	.	.
cord-256187-ofp7tupv	64	1	In	in	IN
cord-256187-ofp7tupv	64	2	addition	addition	NN
cord-256187-ofp7tupv	64	3	,	,	,
cord-256187-ofp7tupv	64	4	we	-PRON-	PRP
cord-256187-ofp7tupv	64	5	will	will	MD
cord-256187-ofp7tupv	64	6	discuss	discuss	VB
cord-256187-ofp7tupv	64	7	how	how	WRB
cord-256187-ofp7tupv	64	8	tetherin	tetherin	NNP
cord-256187-ofp7tupv	64	9	and	and	CC
cord-256187-ofp7tupv	64	10	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	64	11	block	block	VBP
cord-256187-ofp7tupv	64	12	filovirus	filovirus	NN
cord-256187-ofp7tupv	64	13	infection	infection	NN
cord-256187-ofp7tupv	64	14	.	.	.
cord-256187-ofp7tupv	65	1	The	the	DT
cord-256187-ofp7tupv	65	2	interferon	interferon	NN
cord-256187-ofp7tupv	65	3	system	system	NN
cord-256187-ofp7tupv	65	4	constitutes	constitute	VBZ
cord-256187-ofp7tupv	65	5	a	a	DT
cord-256187-ofp7tupv	65	6	major	major	JJ
cord-256187-ofp7tupv	65	7	innate	innate	JJ
cord-256187-ofp7tupv	65	8	defence	defence	NN
cord-256187-ofp7tupv	65	9	against	against	IN
cord-256187-ofp7tupv	65	10	infections	infection	NNS
cord-256187-ofp7tupv	65	11	by	by	IN
cord-256187-ofp7tupv	65	12	viruses	virus	NNS
cord-256187-ofp7tupv	65	13	and	and	CC
cord-256187-ofp7tupv	65	14	other	other	JJ
cord-256187-ofp7tupv	65	15	pathogens	pathogen	NNS
cord-256187-ofp7tupv	65	16	.	.	.
cord-256187-ofp7tupv	66	1	The	the	DT
cord-256187-ofp7tupv	66	2	components	component	NNS
cord-256187-ofp7tupv	66	3	and	and	CC
cord-256187-ofp7tupv	66	4	signalling	signal	VBG
cord-256187-ofp7tupv	66	5	pathways	pathway	NNS
cord-256187-ofp7tupv	66	6	of	of	IN
cord-256187-ofp7tupv	66	7	the	the	DT
cord-256187-ofp7tupv	66	8	IFN	IFN	NNP
cord-256187-ofp7tupv	66	9	system	system	NN
cord-256187-ofp7tupv	66	10	have	have	VBP
cord-256187-ofp7tupv	66	11	been	be	VBN
cord-256187-ofp7tupv	66	12	described	describe	VBN
cord-256187-ofp7tupv	66	13	in	in	IN
cord-256187-ofp7tupv	66	14	several	several	JJ
cord-256187-ofp7tupv	66	15	recent	recent	JJ
cord-256187-ofp7tupv	66	16	reviews	review	NNS
cord-256187-ofp7tupv	66	17	(	(	-LRB-
cord-256187-ofp7tupv	66	18	García	García	NNP
cord-256187-ofp7tupv	66	19	-	-	HYPH
cord-256187-ofp7tupv	66	20	Sastre	Sastre	NNP
cord-256187-ofp7tupv	66	21	and	and	CC
cord-256187-ofp7tupv	66	22	Biron	Biron	NNP
cord-256187-ofp7tupv	66	23	,	,	,
cord-256187-ofp7tupv	66	24	2006	2006	CD
cord-256187-ofp7tupv	66	25	;	;	:
cord-256187-ofp7tupv	66	26	Baum	Baum	NNP
cord-256187-ofp7tupv	66	27	and	and	CC
cord-256187-ofp7tupv	66	28	García	García	NNP
cord-256187-ofp7tupv	66	29	-	-	HYPH
cord-256187-ofp7tupv	66	30	Sastre	Sastre	NNP
cord-256187-ofp7tupv	66	31	,	,	,
cord-256187-ofp7tupv	66	32	2010	2010	CD
cord-256187-ofp7tupv	66	33	;	;	:
cord-256187-ofp7tupv	66	34	Liu	Liu	NNP
cord-256187-ofp7tupv	66	35	et	et	NNP
cord-256187-ofp7tupv	66	36	al	al	NNP
cord-256187-ofp7tupv	66	37	.	.	NNP
cord-256187-ofp7tupv	66	38	,	,	,
cord-256187-ofp7tupv	66	39	2011	2011	CD
cord-256187-ofp7tupv	66	40	)	)	-RRB-
cord-256187-ofp7tupv	66	41	and	and	CC
cord-256187-ofp7tupv	66	42	are	be	VBP
cord-256187-ofp7tupv	66	43	only	only	RB
cord-256187-ofp7tupv	66	44	briefly	briefly	RB
cord-256187-ofp7tupv	66	45	summarized	summarize	VBN
cord-256187-ofp7tupv	66	46	here	here	RB
cord-256187-ofp7tupv	66	47	.	.	.
cord-256187-ofp7tupv	67	1	Three	three	CD
cord-256187-ofp7tupv	67	2	classes	class	NNS
cord-256187-ofp7tupv	67	3	of	of	IN
cord-256187-ofp7tupv	67	4	IFNs	ifn	NNS
cord-256187-ofp7tupv	67	5	have	have	VBP
cord-256187-ofp7tupv	67	6	been	be	VBN
cord-256187-ofp7tupv	67	7	defined	define	VBN
cord-256187-ofp7tupv	67	8	according	accord	VBG
cord-256187-ofp7tupv	67	9	to	to	IN
cord-256187-ofp7tupv	67	10	the	the	DT
cord-256187-ofp7tupv	67	11	receptors	receptor	NNS
cord-256187-ofp7tupv	67	12	bound	bind	VBN
cord-256187-ofp7tupv	67	13	by	by	IN
cord-256187-ofp7tupv	67	14	these	these	DT
cord-256187-ofp7tupv	67	15	cytokines	cytokine	NNS
cord-256187-ofp7tupv	67	16	.	.	.
cord-256187-ofp7tupv	68	1	Type	type	NN
cord-256187-ofp7tupv	68	2	I	-PRON-	PRP
cord-256187-ofp7tupv	68	3	IFN	IFN	NNP
cord-256187-ofp7tupv	68	4	,	,	,
cord-256187-ofp7tupv	68	5	including	include	VBG
cord-256187-ofp7tupv	68	6	IFNa	IFNa	NNS
cord-256187-ofp7tupv	68	7	and	and	CC
cord-256187-ofp7tupv	68	8	IFNb	IFNb	NNS
cord-256187-ofp7tupv	68	9	,	,	,
cord-256187-ofp7tupv	68	10	are	be	VBP
cord-256187-ofp7tupv	68	11	produced	produce	VBN
cord-256187-ofp7tupv	68	12	by	by	IN
cord-256187-ofp7tupv	68	13	many	many	JJ
cord-256187-ofp7tupv	68	14	cell	cell	NN
cord-256187-ofp7tupv	68	15	types	type	NNS
cord-256187-ofp7tupv	68	16	as	as	IN
cord-256187-ofp7tupv	68	17	a	a	DT
cord-256187-ofp7tupv	68	18	direct	direct	JJ
cord-256187-ofp7tupv	68	19	result	result	NN
cord-256187-ofp7tupv	68	20	of	of	IN
cord-256187-ofp7tupv	68	21	viral	viral	JJ
cord-256187-ofp7tupv	68	22	infection	infection	NN
cord-256187-ofp7tupv	68	23	.	.	.
cord-256187-ofp7tupv	69	1	IFNc	IFNc	NNP
cord-256187-ofp7tupv	69	2	,	,	,
cord-256187-ofp7tupv	69	3	the	the	DT
cord-256187-ofp7tupv	69	4	only	only	JJ
cord-256187-ofp7tupv	69	5	type	type	NN
cord-256187-ofp7tupv	69	6	II	II	NNP
cord-256187-ofp7tupv	69	7	IFN	IFN	NNP
cord-256187-ofp7tupv	69	8	,	,	,
cord-256187-ofp7tupv	69	9	is	be	VBZ
cord-256187-ofp7tupv	69	10	generated	generate	VBN
cord-256187-ofp7tupv	69	11	by	by	IN
cord-256187-ofp7tupv	69	12	activated	activate	VBN
cord-256187-ofp7tupv	69	13	T	T	NNP
cord-256187-ofp7tupv	69	14	cells	cell	NNS
cord-256187-ofp7tupv	69	15	and	and	CC
cord-256187-ofp7tupv	69	16	NK	NK	NNP
cord-256187-ofp7tupv	69	17	cells	cell	NNS
cord-256187-ofp7tupv	69	18	.	.	.
cord-256187-ofp7tupv	70	1	Type	Type	NNP
cord-256187-ofp7tupv	70	2	III	III	NNP
cord-256187-ofp7tupv	70	3	IFNs	ifn	NNS
cord-256187-ofp7tupv	70	4	,	,	,
cord-256187-ofp7tupv	70	5	which	which	WDT
cord-256187-ofp7tupv	70	6	include	include	VBP
cord-256187-ofp7tupv	70	7	IFNk1	IFNk1	NNP
cord-256187-ofp7tupv	70	8	-	-	HYPH
cord-256187-ofp7tupv	70	9	3	3	NNP
cord-256187-ofp7tupv	70	10	,	,	,
cord-256187-ofp7tupv	70	11	are	be	VBP
cord-256187-ofp7tupv	70	12	incompletely	incompletely	RB
cord-256187-ofp7tupv	70	13	characterized	characterize	VBN
cord-256187-ofp7tupv	70	14	,	,	,
cord-256187-ofp7tupv	70	15	but	but	CC
cord-256187-ofp7tupv	70	16	are	be	VBP
cord-256187-ofp7tupv	70	17	believed	believe	VBN
cord-256187-ofp7tupv	70	18	to	to	TO
cord-256187-ofp7tupv	70	19	regulate	regulate	VB
cord-256187-ofp7tupv	70	20	the	the	DT
cord-256187-ofp7tupv	70	21	antiviral	antiviral	JJ
cord-256187-ofp7tupv	70	22	response	response	NN
cord-256187-ofp7tupv	70	23	.	.	.
cord-256187-ofp7tupv	71	1	The	the	DT
cord-256187-ofp7tupv	71	2	IFN	IFN	NNP
cord-256187-ofp7tupv	71	3	system	system	NN
cord-256187-ofp7tupv	71	4	integrates	integrate	VBZ
cord-256187-ofp7tupv	71	5	two	two	CD
cord-256187-ofp7tupv	71	6	major	major	JJ
cord-256187-ofp7tupv	71	7	sensor	sensor	NN
cord-256187-ofp7tupv	71	8	and	and	CC
cord-256187-ofp7tupv	71	9	signalling	signal	VBG
cord-256187-ofp7tupv	71	10	networks	network	NNS
cord-256187-ofp7tupv	71	11	.	.	.
cord-256187-ofp7tupv	72	1	In	in	IN
cord-256187-ofp7tupv	72	2	cells	cell	NNS
cord-256187-ofp7tupv	72	3	exposed	expose	VBN
cord-256187-ofp7tupv	72	4	to	to	IN
cord-256187-ofp7tupv	72	5	viruses	virus	NNS
cord-256187-ofp7tupv	72	6	,	,	,
cord-256187-ofp7tupv	72	7	receptors	receptor	NNS
cord-256187-ofp7tupv	72	8	for	for	IN
cord-256187-ofp7tupv	72	9	pathogen	pathogen	NN
cord-256187-ofp7tupv	72	10	-	-	HYPH
cord-256187-ofp7tupv	72	11	associated	associate	VBN
cord-256187-ofp7tupv	72	12	molecular	molecular	JJ
cord-256187-ofp7tupv	72	13	patterns	pattern	NNS
cord-256187-ofp7tupv	72	14	sense	sense	VBP
cord-256187-ofp7tupv	72	15	the	the	DT
cord-256187-ofp7tupv	72	16	presence	presence	NN
cord-256187-ofp7tupv	72	17	of	of	IN
cord-256187-ofp7tupv	72	18	the	the	DT
cord-256187-ofp7tupv	72	19	invading	invade	VBG
cord-256187-ofp7tupv	72	20	pathogens	pathogen	NNS
cord-256187-ofp7tupv	72	21	.	.	.
cord-256187-ofp7tupv	73	1	These	these	DT
cord-256187-ofp7tupv	73	2	receptors	receptor	NNS
cord-256187-ofp7tupv	73	3	are	be	VBP
cord-256187-ofp7tupv	73	4	located	locate	VBN
cord-256187-ofp7tupv	73	5	in	in	IN
cord-256187-ofp7tupv	73	6	the	the	DT
cord-256187-ofp7tupv	73	7	cytoplasm	cytoplasm	NN
cord-256187-ofp7tupv	73	8	,	,	,
cord-256187-ofp7tupv	73	9	like	like	IN
cord-256187-ofp7tupv	73	10	retinoic	retinoic	JJ
cord-256187-ofp7tupv	73	11	acid	acid	NN
cord-256187-ofp7tupv	73	12	-	-	HYPH
cord-256187-ofp7tupv	73	13	inducible	inducible	JJ
cord-256187-ofp7tupv	73	14	gene	gene	NN
cord-256187-ofp7tupv	73	15	I	i	NN
cord-256187-ofp7tupv	73	16	(	(	-LRB-
cord-256187-ofp7tupv	73	17	RIG	rig	NN
cord-256187-ofp7tupv	73	18	-	-	:
cord-256187-ofp7tupv	73	19	I	i	NN
cord-256187-ofp7tupv	73	20	)	)	-RRB-
cord-256187-ofp7tupv	73	21	and	and	CC
cord-256187-ofp7tupv	73	22	melanoma	melanoma	NN
cord-256187-ofp7tupv	73	23	differentiation	differentiation	NN
cord-256187-ofp7tupv	73	24	-	-	HYPH
cord-256187-ofp7tupv	73	25	associated	associate	VBN
cord-256187-ofp7tupv	73	26	gene	gene	NN
cord-256187-ofp7tupv	73	27	5	5	CD
cord-256187-ofp7tupv	73	28	(	(	-LRB-
cord-256187-ofp7tupv	73	29	MDA-5	MDA-5	NNP
cord-256187-ofp7tupv	73	30	)	)	-RRB-
cord-256187-ofp7tupv	73	31	,	,	,
cord-256187-ofp7tupv	73	32	or	or	CC
cord-256187-ofp7tupv	73	33	in	in	IN
cord-256187-ofp7tupv	73	34	the	the	DT
cord-256187-ofp7tupv	73	35	extracytoplasmic	extracytoplasmic	JJ
cord-256187-ofp7tupv	73	36	space	space	NN
cord-256187-ofp7tupv	73	37	,	,	,
cord-256187-ofp7tupv	73	38	like	like	IN
cord-256187-ofp7tupv	73	39	Toll	toll	NN
cord-256187-ofp7tupv	73	40	-	-	HYPH
cord-256187-ofp7tupv	73	41	like	like	JJ
cord-256187-ofp7tupv	73	42	receptor	receptor	NN
cord-256187-ofp7tupv	73	43	(	(	-LRB-
cord-256187-ofp7tupv	73	44	TLR)-3	TLR)-3	NNP
cord-256187-ofp7tupv	73	45	and	and	CC
cord-256187-ofp7tupv	73	46	TLR-7/8/9	TLR-7/8/9	NNP
cord-256187-ofp7tupv	73	47	,	,	,
cord-256187-ofp7tupv	73	48	and	and	CC
cord-256187-ofp7tupv	73	49	,	,	,
cord-256187-ofp7tupv	73	50	upon	upon	IN
cord-256187-ofp7tupv	73	51	pathogen	pathogen	NN
cord-256187-ofp7tupv	73	52	recognition	recognition	NN
cord-256187-ofp7tupv	73	53	,	,	,
cord-256187-ofp7tupv	73	54	induce	induce	VB
cord-256187-ofp7tupv	73	55	IFN	IFN	NNP
cord-256187-ofp7tupv	73	56	regulatory	regulatory	JJ
cord-256187-ofp7tupv	73	57	factor	factor	NN
cord-256187-ofp7tupv	73	58	(	(	-LRB-
cord-256187-ofp7tupv	73	59	IRF)-3-and	IRF)-3-and	NNP
cord-256187-ofp7tupv	73	60	IRF-7dependent	irf-7dependent	NN
cord-256187-ofp7tupv	73	61	signalling	signal	VBG
cord-256187-ofp7tupv	73	62	cascades	cascade	NNS
cord-256187-ofp7tupv	73	63	that	that	WDT
cord-256187-ofp7tupv	73	64	lead	lead	VBP
cord-256187-ofp7tupv	73	65	to	to	IN
cord-256187-ofp7tupv	73	66	the	the	DT
cord-256187-ofp7tupv	73	67	expression	expression	NN
cord-256187-ofp7tupv	73	68	of	of	IN
cord-256187-ofp7tupv	73	69	type	type	NN
cord-256187-ofp7tupv	73	70	I	-PRON-	PRP
cord-256187-ofp7tupv	73	71	IFNs	ifns	VBP
cord-256187-ofp7tupv	73	72	(	(	-LRB-
cord-256187-ofp7tupv	73	73	Fig	Fig	NNP
cord-256187-ofp7tupv	73	74	.	.	NNP
cord-256187-ofp7tupv	73	75	2	2	CD
cord-256187-ofp7tupv	73	76	)	)	-RRB-
cord-256187-ofp7tupv	73	77	.	.	.
cord-256187-ofp7tupv	74	1	Secreted	secreted	JJ
cord-256187-ofp7tupv	74	2	type	type	NN
cord-256187-ofp7tupv	74	3	I	-PRON-	PRP
cord-256187-ofp7tupv	74	4	IFNs	ifns	VBP
cord-256187-ofp7tupv	74	5	then	then	RB
cord-256187-ofp7tupv	74	6	bind	bind	VB
cord-256187-ofp7tupv	74	7	to	to	IN
cord-256187-ofp7tupv	74	8	cells	cell	NNS
cord-256187-ofp7tupv	74	9	expressing	express	VBG
cord-256187-ofp7tupv	74	10	the	the	DT
cord-256187-ofp7tupv	74	11	type	type	NN
cord-256187-ofp7tupv	75	1	I	-PRON-	PRP
cord-256187-ofp7tupv	75	2	IFN	IFN	NNP
cord-256187-ofp7tupv	75	3	receptor	receptor	NN
cord-256187-ofp7tupv	75	4	,	,	,
cord-256187-ofp7tupv	75	5	which	which	WDT
cord-256187-ofp7tupv	75	6	consists	consist	VBZ
cord-256187-ofp7tupv	75	7	of	of	IN
cord-256187-ofp7tupv	75	8	two	two	CD
cord-256187-ofp7tupv	75	9	subunits	subunit	NNS
cord-256187-ofp7tupv	75	10	,	,	,
cord-256187-ofp7tupv	75	11	IFNa	IFNa	NNS
cord-256187-ofp7tupv	75	12	receptor	receptor	NNP
cord-256187-ofp7tupv	75	13	1	1	CD
cord-256187-ofp7tupv	75	14	(	(	-LRB-
cord-256187-ofp7tupv	75	15	IFNAR1	IFNAR1	NNP
cord-256187-ofp7tupv	75	16	)	)	-RRB-
cord-256187-ofp7tupv	75	17	and	and	CC
cord-256187-ofp7tupv	75	18	IFNAR2	IFNAR2	NNS
cord-256187-ofp7tupv	75	19	.	.	.
cord-256187-ofp7tupv	76	1	Ligand	ligand	NN
cord-256187-ofp7tupv	76	2	binding	bind	VBG
cord-256187-ofp7tupv	76	3	to	to	IN
cord-256187-ofp7tupv	76	4	IFNAR1	ifnar1	NN
cord-256187-ofp7tupv	76	5	and	and	CC
cord-256187-ofp7tupv	76	6	IFNAR2	IFNAR2	NNP
cord-256187-ofp7tupv	76	7	triggers	trigger	VBZ
cord-256187-ofp7tupv	76	8	receptor	receptor	NN
cord-256187-ofp7tupv	76	9	dimerization	dimerization	NN
cord-256187-ofp7tupv	76	10	and	and	CC
cord-256187-ofp7tupv	76	11	signalling	signalling	NN
cord-256187-ofp7tupv	76	12	.	.	.
cord-256187-ofp7tupv	77	1	STAT1	STAT1	NNP
cord-256187-ofp7tupv	77	2	and	and	CC
cord-256187-ofp7tupv	77	3	STAT2	STAT2	NNS
cord-256187-ofp7tupv	77	4	are	be	VBP
cord-256187-ofp7tupv	77	5	integral	integral	JJ
cord-256187-ofp7tupv	77	6	components	component	NNS
cord-256187-ofp7tupv	77	7	of	of	IN
cord-256187-ofp7tupv	77	8	the	the	DT
cord-256187-ofp7tupv	77	9	signalling	signal	VBG
cord-256187-ofp7tupv	77	10	pathway	pathway	NN
cord-256187-ofp7tupv	77	11	induced	induce	VBN
cord-256187-ofp7tupv	77	12	by	by	IN
cord-256187-ofp7tupv	77	13	IFNARs	IFNARs	''
cord-256187-ofp7tupv	77	14	(	(	-LRB-
cord-256187-ofp7tupv	77	15	Fig	fig	NN
cord-256187-ofp7tupv	77	16	.	.	NNP
cord-256187-ofp7tupv	77	17	2	2	CD
cord-256187-ofp7tupv	77	18	)	)	-RRB-
cord-256187-ofp7tupv	77	19	.	.	.
cord-256187-ofp7tupv	78	1	Homodimers	homodimer	NNS
cord-256187-ofp7tupv	78	2	of	of	IN
cord-256187-ofp7tupv	78	3	STAT1	stat1	NN
cord-256187-ofp7tupv	78	4	bind	bind	NN
cord-256187-ofp7tupv	78	5	to	to	IN
cord-256187-ofp7tupv	78	6	IFNcactivated	ifncactivate	VBN
cord-256187-ofp7tupv	78	7	sites	site	NNS
cord-256187-ofp7tupv	78	8	(	(	-LRB-
cord-256187-ofp7tupv	78	9	GAS	gas	NN
cord-256187-ofp7tupv	78	10	)	)	-RRB-
cord-256187-ofp7tupv	78	11	,	,	,
cord-256187-ofp7tupv	78	12	while	while	IN
cord-256187-ofp7tupv	78	13	STAT1	stat1	NN
cord-256187-ofp7tupv	78	14	/	/	SYM
cord-256187-ofp7tupv	78	15	STAT2	STAT2	NNS
cord-256187-ofp7tupv	78	16	heterodimers	heterodimer	NNS
cord-256187-ofp7tupv	78	17	recognize	recognize	VBP
cord-256187-ofp7tupv	78	18	IFN	IFN	NNP
cord-256187-ofp7tupv	78	19	-	-	HYPH
cord-256187-ofp7tupv	78	20	stimulated	stimulate	VBN
cord-256187-ofp7tupv	78	21	response	response	NN
cord-256187-ofp7tupv	78	22	elements	element	NNS
cord-256187-ofp7tupv	78	23	,	,	,
cord-256187-ofp7tupv	78	24	resulting	result	VBG
cord-256187-ofp7tupv	78	25	in	in	IN
cord-256187-ofp7tupv	78	26	the	the	DT
cord-256187-ofp7tupv	78	27	transcription	transcription	NN
cord-256187-ofp7tupv	78	28	of	of	IN
cord-256187-ofp7tupv	78	29	ISGs	isg	NNS
cord-256187-ofp7tupv	78	30	,	,	,
cord-256187-ofp7tupv	78	31	many	many	JJ
cord-256187-ofp7tupv	78	32	of	of	IN
cord-256187-ofp7tupv	78	33	which	which	WDT
cord-256187-ofp7tupv	78	34	have	have	VBP
cord-256187-ofp7tupv	78	35	antiviral	antiviral	JJ
cord-256187-ofp7tupv	78	36	activity	activity	NN
cord-256187-ofp7tupv	78	37	,	,	,
cord-256187-ofp7tupv	78	38	like	like	IN
cord-256187-ofp7tupv	78	39	the	the	DT
cord-256187-ofp7tupv	78	40	well	well	RB
cord-256187-ofp7tupv	78	41	-	-	HYPH
cord-256187-ofp7tupv	78	42	characterized	characterize	VBN
cord-256187-ofp7tupv	78	43	myxovirus	myxovirus	JJ
cord-256187-ofp7tupv	78	44	resistance	resistance	NN
cord-256187-ofp7tupv	78	45	guanosine	guanosine	NN
cord-256187-ofp7tupv	78	46	triphosphatases	triphosphatase	NNS
cord-256187-ofp7tupv	78	47	(	(	-LRB-
cord-256187-ofp7tupv	78	48	Mx	Mx	NNP
cord-256187-ofp7tupv	78	49	GTPases	GTPases	NNP
cord-256187-ofp7tupv	78	50	)	)	-RRB-
cord-256187-ofp7tupv	79	1	(	(	-LRB-
cord-256187-ofp7tupv	79	2	Haller	Haller	NNP
cord-256187-ofp7tupv	79	3	et	et	NNP
cord-256187-ofp7tupv	79	4	al	al	NNP
cord-256187-ofp7tupv	79	5	.	.	NNP
cord-256187-ofp7tupv	79	6	,	,	,
cord-256187-ofp7tupv	79	7	2007	2007	CD
cord-256187-ofp7tupv	79	8	;	;	:
cord-256187-ofp7tupv	79	9	Sadler	Sadler	NNP
cord-256187-ofp7tupv	79	10	and	and	CC
cord-256187-ofp7tupv	79	11	Williams	Williams	NNP
cord-256187-ofp7tupv	79	12	,	,	,
cord-256187-ofp7tupv	79	13	2008	2008	CD
cord-256187-ofp7tupv	79	14	)	)	-RRB-
cord-256187-ofp7tupv	79	15	.	.	.
cord-256187-ofp7tupv	80	1	However	however	RB
cord-256187-ofp7tupv	80	2	,	,	,
cord-256187-ofp7tupv	80	3	the	the	DT
cord-256187-ofp7tupv	80	4	full	full	JJ
cord-256187-ofp7tupv	80	5	spectrum	spectrum	NN
cord-256187-ofp7tupv	80	6	of	of	IN
cord-256187-ofp7tupv	80	7	ISGs	ISGs	NNP
cord-256187-ofp7tupv	80	8	has	have	VBZ
cord-256187-ofp7tupv	80	9	only	only	RB
cord-256187-ofp7tupv	80	10	been	be	VBN
cord-256187-ofp7tupv	80	11	recently	recently	RB
cord-256187-ofp7tupv	80	12	characterized	characterize	VBN
cord-256187-ofp7tupv	80	13	(	(	-LRB-
cord-256187-ofp7tupv	80	14	Schoggins	Schoggins	NNP
cord-256187-ofp7tupv	80	15	et	et	NNP
cord-256187-ofp7tupv	80	16	al	al	NNP
cord-256187-ofp7tupv	80	17	.	.	NNP
cord-256187-ofp7tupv	80	18	,	,	,
cord-256187-ofp7tupv	80	19	2011	2011	CD
cord-256187-ofp7tupv	80	20	)	)	-RRB-
cord-256187-ofp7tupv	80	21	,	,	,
cord-256187-ofp7tupv	80	22	and	and	CC
cord-256187-ofp7tupv	80	23	novel	novel	NN
cord-256187-ofp7tupv	80	24	ISGs	isg	NNS
cord-256187-ofp7tupv	80	25	that	that	WDT
cord-256187-ofp7tupv	80	26	target	target	VBP
cord-256187-ofp7tupv	80	27	discrete	discrete	JJ
cord-256187-ofp7tupv	80	28	steps	step	NNS
cord-256187-ofp7tupv	80	29	in	in	IN
cord-256187-ofp7tupv	80	30	the	the	DT
cord-256187-ofp7tupv	80	31	viral	viral	JJ
cord-256187-ofp7tupv	80	32	life	life	NN
cord-256187-ofp7tupv	80	33	cycle	cycle	NN
cord-256187-ofp7tupv	80	34	,	,	,
cord-256187-ofp7tupv	80	35	like	like	IN
cord-256187-ofp7tupv	80	36	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	80	37	and	and	CC
cord-256187-ofp7tupv	80	38	tetherin	tetherin	NNP
cord-256187-ofp7tupv	80	39	,	,	,
cord-256187-ofp7tupv	80	40	have	have	VBP
cord-256187-ofp7tupv	80	41	been	be	VBN
cord-256187-ofp7tupv	80	42	identified	identify	VBN
cord-256187-ofp7tupv	80	43	,	,	,
cord-256187-ofp7tupv	80	44	as	as	IN
cord-256187-ofp7tupv	80	45	discussed	discuss	VBN
cord-256187-ofp7tupv	80	46	below	below	RB
cord-256187-ofp7tupv	80	47	.	.	.
cord-256187-ofp7tupv	81	1	VP24	VP24	NNP
cord-256187-ofp7tupv	81	2	is	be	VBZ
cord-256187-ofp7tupv	81	3	the	the	DT
cord-256187-ofp7tupv	81	4	smallest	small	JJS
cord-256187-ofp7tupv	81	5	of	of	IN
cord-256187-ofp7tupv	81	6	the	the	DT
cord-256187-ofp7tupv	81	7	seven	seven	CD
cord-256187-ofp7tupv	81	8	EBOV	EBOV	NNP
cord-256187-ofp7tupv	81	9	-	-	HYPH
cord-256187-ofp7tupv	81	10	encoded	encode	VBN
cord-256187-ofp7tupv	81	11	structural	structural	JJ
cord-256187-ofp7tupv	81	12	proteins	protein	NNS
cord-256187-ofp7tupv	81	13	and	and	CC
cord-256187-ofp7tupv	81	14	constitutes	constitute	VBZ
cord-256187-ofp7tupv	81	15	the	the	DT
cord-256187-ofp7tupv	81	16	minor	minor	JJ
cord-256187-ofp7tupv	81	17	matrix	matrix	NN
cord-256187-ofp7tupv	81	18	protein	protein	NN
cord-256187-ofp7tupv	81	19	relative	relative	JJ
cord-256187-ofp7tupv	81	20	to	to	IN
cord-256187-ofp7tupv	81	21	the	the	DT
cord-256187-ofp7tupv	81	22	major	major	JJ
cord-256187-ofp7tupv	81	23	matrix	matrix	NN
cord-256187-ofp7tupv	81	24	protein	protein	NN
cord-256187-ofp7tupv	82	1	VP40	VP40	NNP
cord-256187-ofp7tupv	83	1	(	(	-LRB-
cord-256187-ofp7tupv	83	2	Han	Han	NNP
cord-256187-ofp7tupv	83	3	et	et	NNP
cord-256187-ofp7tupv	83	4	al	al	NNP
cord-256187-ofp7tupv	83	5	.	.	NNP
cord-256187-ofp7tupv	83	6	,	,	,
cord-256187-ofp7tupv	83	7	2003	2003	CD
cord-256187-ofp7tupv	83	8	)	)	-RRB-
cord-256187-ofp7tupv	83	9	.	.	.
cord-256187-ofp7tupv	84	1	It	-PRON-	PRP
cord-256187-ofp7tupv	84	2	is	be	VBZ
cord-256187-ofp7tupv	84	3	required	require	VBN
cord-256187-ofp7tupv	84	4	for	for	IN
cord-256187-ofp7tupv	84	5	the	the	DT
cord-256187-ofp7tupv	84	6	assembly	assembly	NN
cord-256187-ofp7tupv	84	7	of	of	IN
cord-256187-ofp7tupv	84	8	fully	fully	RB
cord-256187-ofp7tupv	84	9	functional	functional	JJ
cord-256187-ofp7tupv	84	10	nucleocapsids	nucleocapsid	NNS
cord-256187-ofp7tupv	84	11	(	(	-LRB-
cord-256187-ofp7tupv	84	12	Huang	Huang	NNP
cord-256187-ofp7tupv	84	13	et	et	NNP
cord-256187-ofp7tupv	84	14	al	al	NNP
cord-256187-ofp7tupv	84	15	.	.	.
cord-256187-ofp7tupv	85	1	,	,	,
cord-256187-ofp7tupv	85	2	2002	2002	CD
cord-256187-ofp7tupv	85	3	;	;	:
cord-256187-ofp7tupv	85	4	Hoenen	Hoenen	NNP
cord-256187-ofp7tupv	85	5	et	et	NNP
cord-256187-ofp7tupv	85	6	al	al	NNP
cord-256187-ofp7tupv	85	7	.	.	NNP
cord-256187-ofp7tupv	85	8	,	,	,
cord-256187-ofp7tupv	85	9	2006	2006	CD
cord-256187-ofp7tupv	85	10	)	)	-RRB-
cord-256187-ofp7tupv	85	11	and	and	CC
cord-256187-ofp7tupv	85	12	contributes	contribute	VBZ
cord-256187-ofp7tupv	85	13	to	to	IN
cord-256187-ofp7tupv	85	14	the	the	DT
cord-256187-ofp7tupv	85	15	budding	budding	NN
cord-256187-ofp7tupv	85	16	of	of	IN
cord-256187-ofp7tupv	85	17	virus	virus	NN
cord-256187-ofp7tupv	85	18	-	-	HYPH
cord-256187-ofp7tupv	85	19	like	like	JJ
cord-256187-ofp7tupv	85	20	particles	particle	NNS
cord-256187-ofp7tupv	85	21	(	(	-LRB-
cord-256187-ofp7tupv	85	22	VLPs	vlp	NNS
cord-256187-ofp7tupv	85	23	)	)	-RRB-
cord-256187-ofp7tupv	86	1	(	(	-LRB-
cord-256187-ofp7tupv	86	2	Han	Han	NNP
cord-256187-ofp7tupv	86	3	et	et	NNP
cord-256187-ofp7tupv	86	4	al	al	NNP
cord-256187-ofp7tupv	86	5	.	.	NNP
cord-256187-ofp7tupv	86	6	,	,	,
cord-256187-ofp7tupv	86	7	2003	2003	CD
cord-256187-ofp7tupv	87	1	;	;	:
cord-256187-ofp7tupv	87	2	Licata	Licata	NNP
cord-256187-ofp7tupv	87	3	et	et	NNP
cord-256187-ofp7tupv	87	4	al	al	NNP
cord-256187-ofp7tupv	87	5	.	.	NNP
cord-256187-ofp7tupv	87	6	,	,	,
cord-256187-ofp7tupv	87	7	2004	2004	CD
cord-256187-ofp7tupv	87	8	)	)	-RRB-
cord-256187-ofp7tupv	87	9	.	.	.
cord-256187-ofp7tupv	88	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	88	2	,	,	,
cord-256187-ofp7tupv	88	3	VP24	VP24	NNP
cord-256187-ofp7tupv	88	4	can	can	MD
cord-256187-ofp7tupv	88	5	shut	shut	VB
cord-256187-ofp7tupv	88	6	down	down	RP
cord-256187-ofp7tupv	88	7	the	the	DT
cord-256187-ofp7tupv	88	8	host	host	NN
cord-256187-ofp7tupv	88	9	's	's	POS
cord-256187-ofp7tupv	88	10	IFN	IFN	NNP
cord-256187-ofp7tupv	88	11	-	-	HYPH
cord-256187-ofp7tupv	88	12	a	a	NNP
cord-256187-ofp7tupv	88	13	/	/	SYM
cord-256187-ofp7tupv	88	14	b	b	NN
cord-256187-ofp7tupv	88	15	and	and	CC
cord-256187-ofp7tupv	88	16	IFN	IFN	NNP
cord-256187-ofp7tupv	88	17	-	-	HYPH
cord-256187-ofp7tupv	88	18	c	c	NNP
cord-256187-ofp7tupv	88	19	Recognition	Recognition	NNP
cord-256187-ofp7tupv	88	20	of	of	IN
cord-256187-ofp7tupv	88	21	viral	viral	JJ
cord-256187-ofp7tupv	88	22	pathogen	pathogen	NN
cord-256187-ofp7tupv	88	23	-	-	HYPH
cord-256187-ofp7tupv	88	24	associated	associate	VBN
cord-256187-ofp7tupv	88	25	molecular	molecular	JJ
cord-256187-ofp7tupv	88	26	patterns	pattern	NNS
cord-256187-ofp7tupv	88	27	(	(	-LRB-
cord-256187-ofp7tupv	88	28	PAMPs	PAMPs	NNP
cord-256187-ofp7tupv	88	29	)	)	-RRB-
cord-256187-ofp7tupv	88	30	by	by	IN
cord-256187-ofp7tupv	88	31	PRRs	PRRs	NNP
cord-256187-ofp7tupv	88	32	(	(	-LRB-
cord-256187-ofp7tupv	88	33	purple	purple	NN
cord-256187-ofp7tupv	88	34	)	)	-RRB-
cord-256187-ofp7tupv	88	35	in	in	IN
cord-256187-ofp7tupv	88	36	infected	infected	JJ
cord-256187-ofp7tupv	88	37	cells	cell	NNS
cord-256187-ofp7tupv	88	38	initiates	initiate	VBZ
cord-256187-ofp7tupv	88	39	a	a	DT
cord-256187-ofp7tupv	88	40	signalling	signal	VBG
cord-256187-ofp7tupv	88	41	cascade	cascade	NN
cord-256187-ofp7tupv	88	42	including	include	VBG
cord-256187-ofp7tupv	88	43	adaptor	adaptor	NN
cord-256187-ofp7tupv	88	44	molecules	molecule	NNS
cord-256187-ofp7tupv	88	45	(	(	-LRB-
cord-256187-ofp7tupv	88	46	blue	blue	JJ
cord-256187-ofp7tupv	88	47	)	)	-RRB-
cord-256187-ofp7tupv	88	48	and	and	CC
cord-256187-ofp7tupv	88	49	kinases	kinase	NNS
cord-256187-ofp7tupv	88	50	(	(	-LRB-
cord-256187-ofp7tupv	88	51	green	green	NNP
cord-256187-ofp7tupv	88	52	)	)	-RRB-
cord-256187-ofp7tupv	88	53	,	,	,
cord-256187-ofp7tupv	88	54	which	which	WDT
cord-256187-ofp7tupv	88	55	activate	activate	VBP
cord-256187-ofp7tupv	88	56	transcription	transcription	NN
cord-256187-ofp7tupv	88	57	factors	factor	NNS
cord-256187-ofp7tupv	88	58	(	(	-LRB-
cord-256187-ofp7tupv	88	59	red	red	JJ
cord-256187-ofp7tupv	88	60	)	)	-RRB-
cord-256187-ofp7tupv	88	61	that	that	WDT
cord-256187-ofp7tupv	88	62	induce	induce	VBP
cord-256187-ofp7tupv	88	63	the	the	DT
cord-256187-ofp7tupv	88	64	expression	expression	NN
cord-256187-ofp7tupv	88	65	of	of	IN
cord-256187-ofp7tupv	88	66	type	type	NN
cord-256187-ofp7tupv	88	67	I	-PRON-	PRP
cord-256187-ofp7tupv	88	68	IFNs	ifns	VBP
cord-256187-ofp7tupv	88	69	and	and	CC
cord-256187-ofp7tupv	88	70	ISGs	ISGs	NNPS
cord-256187-ofp7tupv	88	71	(	(	-LRB-
cord-256187-ofp7tupv	88	72	left	left	JJ
cord-256187-ofp7tupv	88	73	panel	panel	NN
cord-256187-ofp7tupv	88	74	)	)	-RRB-
cord-256187-ofp7tupv	88	75	.	.	.
cord-256187-ofp7tupv	89	1	Binding	bind	VBG
cord-256187-ofp7tupv	89	2	of	of	IN
cord-256187-ofp7tupv	89	3	IFN	IFN	NNP
cord-256187-ofp7tupv	89	4	-	-	HYPH
cord-256187-ofp7tupv	89	5	a	a	NNP
cord-256187-ofp7tupv	89	6	/	/	SYM
cord-256187-ofp7tupv	89	7	b	b	NN
cord-256187-ofp7tupv	89	8	and	and	CC
cord-256187-ofp7tupv	89	9	IFN	IFN	NNP
cord-256187-ofp7tupv	89	10	-	-	HYPH
cord-256187-ofp7tupv	89	11	c	c	NNP
cord-256187-ofp7tupv	89	12	to	to	IN
cord-256187-ofp7tupv	89	13	their	-PRON-	PRP$
cord-256187-ofp7tupv	89	14	receptors	receptor	NNS
cord-256187-ofp7tupv	89	15	induces	induce	VBZ
cord-256187-ofp7tupv	89	16	phosphorylation	phosphorylation	NN
cord-256187-ofp7tupv	89	17	(	(	-LRB-
cord-256187-ofp7tupv	89	18	by	by	IN
cord-256187-ofp7tupv	89	19	JAK1	JAK1	NNP
cord-256187-ofp7tupv	89	20	/	/	SYM
cord-256187-ofp7tupv	89	21	TYK2	TYK2	NNP
cord-256187-ofp7tupv	89	22	)	)	-RRB-
cord-256187-ofp7tupv	89	23	,	,	,
cord-256187-ofp7tupv	89	24	dimerization	dimerization	NN
cord-256187-ofp7tupv	89	25	and	and	CC
cord-256187-ofp7tupv	89	26	nuclear	nuclear	JJ
cord-256187-ofp7tupv	89	27	translocation	translocation	NN
cord-256187-ofp7tupv	89	28	of	of	IN
cord-256187-ofp7tupv	89	29	STAT	stat	NN
cord-256187-ofp7tupv	89	30	transcription	transcription	NN
cord-256187-ofp7tupv	89	31	factors	factor	NNS
cord-256187-ofp7tupv	89	32	,	,	,
cord-256187-ofp7tupv	89	33	which	which	WDT
cord-256187-ofp7tupv	89	34	induce	induce	VBP
cord-256187-ofp7tupv	89	35	the	the	DT
cord-256187-ofp7tupv	89	36	expression	expression	NN
cord-256187-ofp7tupv	89	37	of	of	IN
cord-256187-ofp7tupv	89	38	several	several	JJ
cord-256187-ofp7tupv	89	39	ISGs	isg	NNS
cord-256187-ofp7tupv	89	40	such	such	JJ
cord-256187-ofp7tupv	89	41	as	as	IN
cord-256187-ofp7tupv	89	42	tetherin	tetherin	NNP
cord-256187-ofp7tupv	89	43	,	,	,
cord-256187-ofp7tupv	89	44	IFITM	IFITM	NNP
cord-256187-ofp7tupv	89	45	,	,	,
cord-256187-ofp7tupv	89	46	PKR	PKR	NNP
cord-256187-ofp7tupv	89	47	and	and	CC
cord-256187-ofp7tupv	89	48	others	other	NNS
cord-256187-ofp7tupv	89	49	(	(	-LRB-
cord-256187-ofp7tupv	89	50	right	right	JJ
cord-256187-ofp7tupv	89	51	panel	panel	NN
cord-256187-ofp7tupv	89	52	)	)	-RRB-
cord-256187-ofp7tupv	89	53	.	.	.
cord-256187-ofp7tupv	90	1	IFN	IFN	NNP
cord-256187-ofp7tupv	90	2	,	,	,
cord-256187-ofp7tupv	90	3	interferon	interferon	NN
cord-256187-ofp7tupv	90	4	;	;	:
cord-256187-ofp7tupv	90	5	TLR	TLR	NNP
cord-256187-ofp7tupv	90	6	,	,	,
cord-256187-ofp7tupv	90	7	Toll	Toll	NNP
cord-256187-ofp7tupv	90	8	-	-	HYPH
cord-256187-ofp7tupv	90	9	like	like	JJ
cord-256187-ofp7tupv	90	10	receptor	receptor	NN
cord-256187-ofp7tupv	90	11	;	;	:
cord-256187-ofp7tupv	90	12	RIG	rig	NN
cord-256187-ofp7tupv	90	13	-	-	:
cord-256187-ofp7tupv	90	14	I	i	NN
cord-256187-ofp7tupv	90	15	,	,	,
cord-256187-ofp7tupv	90	16	retinoic	retinoic	JJ
cord-256187-ofp7tupv	90	17	acid	acid	NN
cord-256187-ofp7tupv	90	18	-	-	HYPH
cord-256187-ofp7tupv	90	19	inducible	inducible	JJ
cord-256187-ofp7tupv	90	20	gene	gene	NN
cord-256187-ofp7tupv	90	21	I	i	NN
cord-256187-ofp7tupv	90	22	;	;	:
cord-256187-ofp7tupv	90	23	MDA-5	MDA-5	NNP
cord-256187-ofp7tupv	90	24	,	,	,
cord-256187-ofp7tupv	90	25	melanoma	melanoma	NN
cord-256187-ofp7tupv	90	26	differentiation	differentiation	NN
cord-256187-ofp7tupv	90	27	-	-	HYPH
cord-256187-ofp7tupv	90	28	associated	associate	VBN
cord-256187-ofp7tupv	90	29	gene	gene	NN
cord-256187-ofp7tupv	90	30	5	5	CD
cord-256187-ofp7tupv	90	31	;	;	:
cord-256187-ofp7tupv	90	32	MyD88	MyD88	NNS
cord-256187-ofp7tupv	90	33	,	,	,
cord-256187-ofp7tupv	90	34	myeloid	myeloid	JJ
cord-256187-ofp7tupv	90	35	differentiation	differentiation	NN
cord-256187-ofp7tupv	90	36	primary	primary	JJ
cord-256187-ofp7tupv	90	37	response	response	NN
cord-256187-ofp7tupv	90	38	protein	protein	NN
cord-256187-ofp7tupv	90	39	88	88	CD
cord-256187-ofp7tupv	90	40	;	;	:
cord-256187-ofp7tupv	90	41	TRIF	TRIF	NNP
cord-256187-ofp7tupv	90	42	,	,	,
cord-256187-ofp7tupv	90	43	TIR	TIR	NNP
cord-256187-ofp7tupv	90	44	domain	domain	NN
cord-256187-ofp7tupv	90	45	-	-	HYPH
cord-256187-ofp7tupv	90	46	containing	contain	VBG
cord-256187-ofp7tupv	90	47	adaptor	adaptor	NN
cord-256187-ofp7tupv	90	48	-	-	HYPH
cord-256187-ofp7tupv	90	49	inducing	induce	VBG
cord-256187-ofp7tupv	90	50	IFN	IFN	NNP
cord-256187-ofp7tupv	90	51	-	-	HYPH
cord-256187-ofp7tupv	90	52	b	b	NNP
cord-256187-ofp7tupv	90	53	;	;	:
cord-256187-ofp7tupv	90	54	IPS-1	IPS-1	NNP
cord-256187-ofp7tupv	91	1	,	,	,
cord-256187-ofp7tupv	91	2	IFN	IFN	NNP
cord-256187-ofp7tupv	91	3	-	-	HYPH
cord-256187-ofp7tupv	91	4	b	b	NNP
cord-256187-ofp7tupv	91	5	promoter	promoter	NN
cord-256187-ofp7tupv	91	6	stimulator	stimulator	NN
cord-256187-ofp7tupv	91	7	1	1	CD
cord-256187-ofp7tupv	91	8	;	;	:
cord-256187-ofp7tupv	91	9	TRAF6	TRAF6	NNP
cord-256187-ofp7tupv	91	10	,	,	,
cord-256187-ofp7tupv	91	11	tumour	tumour	NN
cord-256187-ofp7tupv	91	12	necrosis	necrosis	NN
cord-256187-ofp7tupv	91	13	factor	factor	NN
cord-256187-ofp7tupv	91	14	receptor	receptor	NN
cord-256187-ofp7tupv	91	15	-	-	HYPH
cord-256187-ofp7tupv	91	16	associated	associate	VBN
cord-256187-ofp7tupv	91	17	factor	factor	NN
cord-256187-ofp7tupv	91	18	6	6	CD
cord-256187-ofp7tupv	91	19	;	;	:
cord-256187-ofp7tupv	91	20	IRAK	IRAK	NNP
cord-256187-ofp7tupv	91	21	,	,	,
cord-256187-ofp7tupv	91	22	interleukin-1	interleukin-1	NNP
cord-256187-ofp7tupv	91	23	receptor	receptor	NN
cord-256187-ofp7tupv	91	24	-	-	HYPH
cord-256187-ofp7tupv	91	25	associated	associate	VBN
cord-256187-ofp7tupv	91	26	kinase	kinase	NN
cord-256187-ofp7tupv	91	27	;	;	:
cord-256187-ofp7tupv	91	28	IKKe	IKKe	NNS
cord-256187-ofp7tupv	91	29	,	,	,
cord-256187-ofp7tupv	91	30	IjB	ijb	NN
cord-256187-ofp7tupv	91	31	kinase	kinase	NN
cord-256187-ofp7tupv	91	32	e	e	NNP
cord-256187-ofp7tupv	91	33	;	;	:
cord-256187-ofp7tupv	91	34	TBK1	TBK1	NNP
cord-256187-ofp7tupv	91	35	,	,	,
cord-256187-ofp7tupv	91	36	tank	tank	NN
cord-256187-ofp7tupv	91	37	-	-	HYPH
cord-256187-ofp7tupv	91	38	binding	binding	NN
cord-256187-ofp7tupv	91	39	kinase	kinase	NN
cord-256187-ofp7tupv	91	40	1	1	CD
cord-256187-ofp7tupv	91	41	;	;	:
cord-256187-ofp7tupv	91	42	IRF	IRF	NNP
cord-256187-ofp7tupv	91	43	,	,	,
cord-256187-ofp7tupv	91	44	IFN	IFN	NNP
cord-256187-ofp7tupv	91	45	regulatory	regulatory	JJ
cord-256187-ofp7tupv	91	46	factor	factor	NN
cord-256187-ofp7tupv	91	47	;	;	:
cord-256187-ofp7tupv	91	48	NF	nf	NN
cord-256187-ofp7tupv	91	49	-	-	HYPH
cord-256187-ofp7tupv	91	50	jB	jB	NNP
cord-256187-ofp7tupv	91	51	,	,	,
cord-256187-ofp7tupv	91	52	nuclear	nuclear	JJ
cord-256187-ofp7tupv	91	53	factor	factor	NN
cord-256187-ofp7tupv	91	54	j	j	NNP
cord-256187-ofp7tupv	91	55	light	light	NNP
cord-256187-ofp7tupv	91	56	chain	chain	NN
cord-256187-ofp7tupv	91	57	enhancer	enhancer	NN
cord-256187-ofp7tupv	91	58	of	of	IN
cord-256187-ofp7tupv	91	59	activated	activate	VBN
cord-256187-ofp7tupv	91	60	B	b	NN
cord-256187-ofp7tupv	91	61	-	-	HYPH
cord-256187-ofp7tupv	91	62	cells	cell	NNS
cord-256187-ofp7tupv	91	63	;	;	:
cord-256187-ofp7tupv	91	64	ISG	ISG	NNP
cord-256187-ofp7tupv	91	65	,	,	,
cord-256187-ofp7tupv	91	66	IFN	IFN	NNP
cord-256187-ofp7tupv	91	67	-	-	HYPH
cord-256187-ofp7tupv	91	68	stimulated	stimulate	VBN
cord-256187-ofp7tupv	91	69	gene	gene	NN
cord-256187-ofp7tupv	91	70	;	;	:
cord-256187-ofp7tupv	91	71	IFNAR	IFNAR	NNP
cord-256187-ofp7tupv	91	72	,	,	,
cord-256187-ofp7tupv	91	73	IFN	IFN	NNP
cord-256187-ofp7tupv	91	74	-	-	:
cord-256187-ofp7tupv	91	75	a	a	DT
cord-256187-ofp7tupv	91	76	receptor	receptor	NN
cord-256187-ofp7tupv	91	77	;	;	:
cord-256187-ofp7tupv	91	78	IFNGR	IFNGR	NNP
cord-256187-ofp7tupv	91	79	,	,	,
cord-256187-ofp7tupv	91	80	IFN	IFN	NNP
cord-256187-ofp7tupv	91	81	-	-	HYPH
cord-256187-ofp7tupv	91	82	c	c	NNP
cord-256187-ofp7tupv	91	83	receptor	receptor	NN
cord-256187-ofp7tupv	91	84	;	;	:
cord-256187-ofp7tupv	91	85	JAK1	JAK1	NNP
cord-256187-ofp7tupv	91	86	,	,	,
cord-256187-ofp7tupv	91	87	Janus	Janus	NNP
cord-256187-ofp7tupv	91	88	-	-	HYPH
cord-256187-ofp7tupv	91	89	activated	activate	VBN
cord-256187-ofp7tupv	91	90	kinase	kinase	NN
cord-256187-ofp7tupv	91	91	1	1	CD
cord-256187-ofp7tupv	91	92	;	;	:
cord-256187-ofp7tupv	91	93	PRR	PRR	NNP
cord-256187-ofp7tupv	91	94	,	,	,
cord-256187-ofp7tupv	91	95	pathogen	pathogen	NN
cord-256187-ofp7tupv	91	96	recognition	recognition	NN
cord-256187-ofp7tupv	91	97	receptor	receptor	NN
cord-256187-ofp7tupv	91	98	;	;	:
cord-256187-ofp7tupv	91	99	TYK2	TYK2	NNP
cord-256187-ofp7tupv	91	100	,	,	,
cord-256187-ofp7tupv	91	101	tyrosine	tyrosine	NN
cord-256187-ofp7tupv	91	102	kinase	kinase	NN
cord-256187-ofp7tupv	91	103	2	2	CD
cord-256187-ofp7tupv	91	104	;	;	:
cord-256187-ofp7tupv	91	105	STAT	stat	NN
cord-256187-ofp7tupv	91	106	,	,	,
cord-256187-ofp7tupv	91	107	signal	signal	NN
cord-256187-ofp7tupv	91	108	transducer	transducer	NN
cord-256187-ofp7tupv	91	109	and	and	CC
cord-256187-ofp7tupv	91	110	activators	activator	NNS
cord-256187-ofp7tupv	91	111	of	of	IN
cord-256187-ofp7tupv	91	112	transcription	transcription	NN
cord-256187-ofp7tupv	91	113	.	.	.
cord-256187-ofp7tupv	92	1	A.	A.	NNP
cord-256187-ofp7tupv	93	1	Kü	Kü	NNP
cord-256187-ofp7tupv	93	2	hl	hl	NNP
cord-256187-ofp7tupv	93	3	and	and	CC
cord-256187-ofp7tupv	94	1	S.	S.	NNP
cord-256187-ofp7tupv	94	2	Pö	Pö	NNP
cord-256187-ofp7tupv	94	3	hlmann	hlmann	NN
cord-256187-ofp7tupv	94	4	response	response	NN
cord-256187-ofp7tupv	94	5	to	to	IN
cord-256187-ofp7tupv	94	6	viral	viral	JJ
cord-256187-ofp7tupv	94	7	infection	infection	NN
cord-256187-ofp7tupv	94	8	(	(	-LRB-
cord-256187-ofp7tupv	94	9	Reid	Reid	NNP
cord-256187-ofp7tupv	94	10	et	et	NNP
cord-256187-ofp7tupv	94	11	al	al	NNP
cord-256187-ofp7tupv	94	12	.	.	NNP
cord-256187-ofp7tupv	94	13	,	,	,
cord-256187-ofp7tupv	94	14	2006	2006	CD
cord-256187-ofp7tupv	94	15	)	)	-RRB-
cord-256187-ofp7tupv	94	16	.	.	.
cord-256187-ofp7tupv	95	1	For	for	IN
cord-256187-ofp7tupv	95	2	this	this	DT
cord-256187-ofp7tupv	95	3	,	,	,
cord-256187-ofp7tupv	95	4	VP24	VP24	NNP
cord-256187-ofp7tupv	95	5	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	95	6	the	the	DT
cord-256187-ofp7tupv	95	7	nuclear	nuclear	JJ
cord-256187-ofp7tupv	95	8	translocation	translocation	NN
cord-256187-ofp7tupv	95	9	of	of	IN
cord-256187-ofp7tupv	95	10	the	the	DT
cord-256187-ofp7tupv	95	11	transcription	transcription	NN
cord-256187-ofp7tupv	95	12	factor	factor	NN
cord-256187-ofp7tupv	95	13	STAT1	stat1	XX
cord-256187-ofp7tupv	96	1	(	(	-LRB-
cord-256187-ofp7tupv	96	2	Reid	Reid	NNP
cord-256187-ofp7tupv	96	3	et	et	NNP
cord-256187-ofp7tupv	96	4	al	al	NNP
cord-256187-ofp7tupv	96	5	.	.	NNP
cord-256187-ofp7tupv	96	6	,	,	,
cord-256187-ofp7tupv	96	7	2006	2006	CD
cord-256187-ofp7tupv	96	8	)	)	-RRB-
cord-256187-ofp7tupv	97	1	(	(	-LRB-
cord-256187-ofp7tupv	97	2	Fig	Fig	NNP
cord-256187-ofp7tupv	97	3	.	.	.
cord-256187-ofp7tupv	98	1	3	3	LS
cord-256187-ofp7tupv	98	2	)	)	-RRB-
cord-256187-ofp7tupv	98	3	,	,	,
cord-256187-ofp7tupv	98	4	a	a	DT
cord-256187-ofp7tupv	98	5	key	key	JJ
cord-256187-ofp7tupv	98	6	component	component	NN
cord-256187-ofp7tupv	98	7	of	of	IN
cord-256187-ofp7tupv	98	8	the	the	DT
cord-256187-ofp7tupv	98	9	IFN	IFN	NNP
cord-256187-ofp7tupv	98	10	-	-	HYPH
cord-256187-ofp7tupv	98	11	induced	induce	VBN
cord-256187-ofp7tupv	98	12	signalling	signal	VBG
cord-256187-ofp7tupv	98	13	pathway	pathway	NN
cord-256187-ofp7tupv	98	14	controlling	control	VBG
cord-256187-ofp7tupv	98	15	the	the	DT
cord-256187-ofp7tupv	98	16	expression	expression	NN
cord-256187-ofp7tupv	98	17	of	of	IN
cord-256187-ofp7tupv	98	18	ISGs	isg	NNS
cord-256187-ofp7tupv	98	19	,	,	,
cord-256187-ofp7tupv	98	20	as	as	IN
cord-256187-ofp7tupv	98	21	discussed	discuss	VBN
cord-256187-ofp7tupv	98	22	below	below	RB
cord-256187-ofp7tupv	98	23	.	.	.
cord-256187-ofp7tupv	99	1	Upon	upon	IN
cord-256187-ofp7tupv	99	2	activation	activation	NN
cord-256187-ofp7tupv	99	3	,	,	,
cord-256187-ofp7tupv	99	4	STAT1	stat1	NN
cord-256187-ofp7tupv	99	5	is	be	VBZ
cord-256187-ofp7tupv	99	6	tyrosine	tyrosine	NN
cord-256187-ofp7tupv	99	7	-	-	HYPH
cord-256187-ofp7tupv	99	8	phosphorylated	phosphorylate	VBN
cord-256187-ofp7tupv	99	9	(	(	-LRB-
cord-256187-ofp7tupv	99	10	PY	py	NN
cord-256187-ofp7tupv	99	11	-	-	HYPH
cord-256187-ofp7tupv	99	12	STAT1	stat1	NN
cord-256187-ofp7tupv	99	13	)	)	-RRB-
cord-256187-ofp7tupv	99	14	and	and	CC
cord-256187-ofp7tupv	99	15	either	either	CC
cord-256187-ofp7tupv	99	16	heterodimerizes	heterodimerize	VBN
cord-256187-ofp7tupv	99	17	with	with	IN
cord-256187-ofp7tupv	99	18	PY	py	NN
cord-256187-ofp7tupv	99	19	-	-	HYPH
cord-256187-ofp7tupv	99	20	STAT2	STAT2	NNS
cord-256187-ofp7tupv	99	21	for	for	IN
cord-256187-ofp7tupv	99	22	type	type	NN
cord-256187-ofp7tupv	100	1	I	-PRON-	PRP
cord-256187-ofp7tupv	100	2	IFN	IFN	NNP
cord-256187-ofp7tupv	100	3	signalling	signal	VBG
cord-256187-ofp7tupv	100	4	or	or	CC
cord-256187-ofp7tupv	100	5	homodimerizes	homodimerize	NNS
cord-256187-ofp7tupv	100	6	with	with	IN
cord-256187-ofp7tupv	100	7	PY	py	NN
cord-256187-ofp7tupv	100	8	-	-	HYPH
cord-256187-ofp7tupv	100	9	STAT1	stat1	NN
cord-256187-ofp7tupv	100	10	for	for	IN
cord-256187-ofp7tupv	100	11	type	type	NN
cord-256187-ofp7tupv	100	12	II	II	NNP
cord-256187-ofp7tupv	100	13	IFN	IFN	NNP
cord-256187-ofp7tupv	100	14	signalling	signal	VBG
cord-256187-ofp7tupv	100	15	.	.	.
cord-256187-ofp7tupv	101	1	The	the	DT
cord-256187-ofp7tupv	101	2	dimerization	dimerization	NN
cord-256187-ofp7tupv	101	3	leads	lead	VBZ
cord-256187-ofp7tupv	101	4	to	to	IN
cord-256187-ofp7tupv	101	5	the	the	DT
cord-256187-ofp7tupv	101	6	exposition	exposition	NN
cord-256187-ofp7tupv	101	7	of	of	IN
cord-256187-ofp7tupv	101	8	a	a	DT
cord-256187-ofp7tupv	101	9	nuclear	nuclear	JJ
cord-256187-ofp7tupv	101	10	localization	localization	NN
cord-256187-ofp7tupv	101	11	signal	signal	NN
cord-256187-ofp7tupv	101	12	(	(	-LRB-
cord-256187-ofp7tupv	101	13	NLS	NLS	NNP
cord-256187-ofp7tupv	101	14	)	)	-RRB-
cord-256187-ofp7tupv	101	15	in	in	IN
cord-256187-ofp7tupv	101	16	STAT1	stat1	NN
cord-256187-ofp7tupv	101	17	,	,	,
cord-256187-ofp7tupv	101	18	which	which	WDT
cord-256187-ofp7tupv	101	19	is	be	VBZ
cord-256187-ofp7tupv	101	20	recognized	recognize	VBN
cord-256187-ofp7tupv	101	21	by	by	IN
cord-256187-ofp7tupv	101	22	the	the	DT
cord-256187-ofp7tupv	101	23	nuclear	nuclear	JJ
cord-256187-ofp7tupv	101	24	import	import	NN
cord-256187-ofp7tupv	101	25	adaptor	adaptor	NN
cord-256187-ofp7tupv	101	26	protein	protein	NNP
cord-256187-ofp7tupv	101	27	importin	importin	NNP
cord-256187-ofp7tupv	102	1	a	a	LS
cord-256187-ofp7tupv	102	2	,	,	,
cord-256187-ofp7tupv	102	3	specifically	specifically	RB
cord-256187-ofp7tupv	102	4	importin	importin	NNP
cord-256187-ofp7tupv	102	5	a5	a5	NNP
cord-256187-ofp7tupv	102	6	,	,	,
cord-256187-ofp7tupv	102	7	a6	a6	NNP
cord-256187-ofp7tupv	102	8	and	and	CC
cord-256187-ofp7tupv	102	9	a7	a7	NNP
cord-256187-ofp7tupv	102	10	(	(	-LRB-
cord-256187-ofp7tupv	102	11	karyopherin	karyopherin	NNP
cord-256187-ofp7tupv	102	12	a1	a1	NNP
cord-256187-ofp7tupv	102	13	,	,	,
cord-256187-ofp7tupv	102	14	a5	a5	NNP
cord-256187-ofp7tupv	102	15	,	,	,
cord-256187-ofp7tupv	102	16	a6	a6	NNP
cord-256187-ofp7tupv	102	17	;	;	:
cord-256187-ofp7tupv	103	1	NP-1	NP-1	NNP
cord-256187-ofp7tupv	103	2	subfamily	subfamily	NN
cord-256187-ofp7tupv	103	3	of	of	IN
cord-256187-ofp7tupv	103	4	importins	importin	NNS
cord-256187-ofp7tupv	103	5	)	)	-RRB-
cord-256187-ofp7tupv	103	6	.	.	.
cord-256187-ofp7tupv	104	1	Importin	Importin	NNP
cord-256187-ofp7tupv	104	2	a	a	DT
cord-256187-ofp7tupv	104	3	is	be	VBZ
cord-256187-ofp7tupv	104	4	then	then	RB
cord-256187-ofp7tupv	104	5	bound	bind	VBN
cord-256187-ofp7tupv	104	6	by	by	IN
cord-256187-ofp7tupv	104	7	the	the	DT
cord-256187-ofp7tupv	104	8	nuclear	nuclear	JJ
cord-256187-ofp7tupv	104	9	import	import	NN
cord-256187-ofp7tupv	104	10	factor	factor	NN
cord-256187-ofp7tupv	105	1	importin	importin	NNP
cord-256187-ofp7tupv	105	2	b	b	NNP
cord-256187-ofp7tupv	105	3	(	(	-LRB-
cord-256187-ofp7tupv	105	4	Sekimoto	Sekimoto	NNP
cord-256187-ofp7tupv	105	5	et	et	NNP
cord-256187-ofp7tupv	105	6	al	al	NNP
cord-256187-ofp7tupv	105	7	.	.	NNP
cord-256187-ofp7tupv	105	8	,	,	,
cord-256187-ofp7tupv	105	9	1997	1997	CD
cord-256187-ofp7tupv	105	10	)	)	-RRB-
cord-256187-ofp7tupv	105	11	,	,	,
cord-256187-ofp7tupv	105	12	which	which	WDT
cord-256187-ofp7tupv	105	13	facilitates	facilitate	VBZ
cord-256187-ofp7tupv	105	14	import	import	NN
cord-256187-ofp7tupv	105	15	of	of	IN
cord-256187-ofp7tupv	105	16	STAT	stat	NN
cord-256187-ofp7tupv	105	17	dimers	dimer	NNS
cord-256187-ofp7tupv	105	18	into	into	IN
cord-256187-ofp7tupv	105	19	the	the	DT
cord-256187-ofp7tupv	105	20	nucleus	nucleus	NN
cord-256187-ofp7tupv	106	1	(	(	-LRB-
cord-256187-ofp7tupv	106	2	Fig	Fig	NNP
cord-256187-ofp7tupv	106	3	.	.	.
cord-256187-ofp7tupv	106	4	3	3	CD
cord-256187-ofp7tupv	106	5	)	)	-RRB-
cord-256187-ofp7tupv	106	6	.	.	.
cord-256187-ofp7tupv	107	1	However	however	RB
cord-256187-ofp7tupv	107	2	,	,	,
cord-256187-ofp7tupv	107	3	in	in	IN
cord-256187-ofp7tupv	107	4	the	the	DT
cord-256187-ofp7tupv	107	5	presence	presence	NN
cord-256187-ofp7tupv	107	6	of	of	IN
cord-256187-ofp7tupv	107	7	VP24	VP24	NNP
cord-256187-ofp7tupv	107	8	,	,	,
cord-256187-ofp7tupv	107	9	which	which	WDT
cord-256187-ofp7tupv	107	10	like	like	IN
cord-256187-ofp7tupv	107	11	STAT1	stat1	NN
cord-256187-ofp7tupv	107	12	binds	bind	VBZ
cord-256187-ofp7tupv	107	13	to	to	IN
cord-256187-ofp7tupv	107	14	importins	importins	NNP
cord-256187-ofp7tupv	107	15	a5	a5	NNP
cord-256187-ofp7tupv	107	16	,	,	,
cord-256187-ofp7tupv	107	17	a6	a6	NNP
cord-256187-ofp7tupv	107	18	and	and	CC
cord-256187-ofp7tupv	107	19	a7	a7	NNP
cord-256187-ofp7tupv	108	1	(	(	-LRB-
cord-256187-ofp7tupv	108	2	Reid	Reid	NNP
cord-256187-ofp7tupv	108	3	et	et	NNP
cord-256187-ofp7tupv	108	4	al	al	NNP
cord-256187-ofp7tupv	108	5	.	.	NNP
cord-256187-ofp7tupv	108	6	,	,	,
cord-256187-ofp7tupv	108	7	2006	2006	CD
cord-256187-ofp7tupv	109	1	(	(	-LRB-
cord-256187-ofp7tupv	109	2	Reid	Reid	NNP
cord-256187-ofp7tupv	109	3	et	et	NNP
cord-256187-ofp7tupv	109	4	al	al	NNP
cord-256187-ofp7tupv	109	5	.	.	.
cord-256187-ofp7tupv	110	1	,	,	,
cord-256187-ofp7tupv	110	2	,	,	,
cord-256187-ofp7tupv	110	3	2007	2007	CD
cord-256187-ofp7tupv	110	4	,	,	,
cord-256187-ofp7tupv	110	5	the	the	DT
cord-256187-ofp7tupv	110	6	recognition	recognition	NN
cord-256187-ofp7tupv	110	7	of	of	IN
cord-256187-ofp7tupv	110	8	the	the	DT
cord-256187-ofp7tupv	110	9	PY	py	NN
cord-256187-ofp7tupv	110	10	-	-	HYPH
cord-256187-ofp7tupv	110	11	STAT1	stat1	NN
cord-256187-ofp7tupv	110	12	NLS	nls	NN
cord-256187-ofp7tupv	110	13	by	by	IN
cord-256187-ofp7tupv	110	14	these	these	DT
cord-256187-ofp7tupv	110	15	importins	importin	NNS
cord-256187-ofp7tupv	110	16	is	be	VBZ
cord-256187-ofp7tupv	110	17	disrupted	disrupt	VBN
cord-256187-ofp7tupv	110	18	,	,	,
cord-256187-ofp7tupv	110	19	and	and	CC
cord-256187-ofp7tupv	110	20	PY	py	NN
cord-256187-ofp7tupv	110	21	-	-	HYPH
cord-256187-ofp7tupv	110	22	STAT1	stat1	NN
cord-256187-ofp7tupv	110	23	is	be	VBZ
cord-256187-ofp7tupv	110	24	not	not	RB
cord-256187-ofp7tupv	110	25	imported	import	VBN
cord-256187-ofp7tupv	110	26	into	into	IN
cord-256187-ofp7tupv	110	27	the	the	DT
cord-256187-ofp7tupv	110	28	nucleus	nucleus	NN
cord-256187-ofp7tupv	110	29	.	.	.
cord-256187-ofp7tupv	111	1	Blockade	blockade	NN
cord-256187-ofp7tupv	111	2	of	of	IN
cord-256187-ofp7tupv	111	3	nuclear	nuclear	JJ
cord-256187-ofp7tupv	111	4	transport	transport	NN
cord-256187-ofp7tupv	111	5	of	of	IN
cord-256187-ofp7tupv	111	6	PY	py	NN
cord-256187-ofp7tupv	111	7	-	-	HYPH
cord-256187-ofp7tupv	111	8	STAT1	stat1	NN
cord-256187-ofp7tupv	111	9	is	be	VBZ
cord-256187-ofp7tupv	111	10	not	not	RB
cord-256187-ofp7tupv	111	11	because	because	IN
cord-256187-ofp7tupv	111	12	of	of	IN
cord-256187-ofp7tupv	111	13	a	a	DT
cord-256187-ofp7tupv	111	14	global	global	JJ
cord-256187-ofp7tupv	111	15	inhibition	inhibition	NN
cord-256187-ofp7tupv	111	16	of	of	IN
cord-256187-ofp7tupv	111	17	nuclear	nuclear	JJ
cord-256187-ofp7tupv	111	18	import	import	NN
cord-256187-ofp7tupv	111	19	,	,	,
cord-256187-ofp7tupv	111	20	as	as	IN
cord-256187-ofp7tupv	111	21	VP24	VP24	NNP
cord-256187-ofp7tupv	111	22	does	do	VBZ
cord-256187-ofp7tupv	111	23	not	not	RB
cord-256187-ofp7tupv	111	24	bind	bind	VB
cord-256187-ofp7tupv	111	25	to	to	IN
cord-256187-ofp7tupv	111	26	importin	importin	NNP
cord-256187-ofp7tupv	111	27	a1	a1	NNP
cord-256187-ofp7tupv	111	28	(	(	-LRB-
cord-256187-ofp7tupv	111	29	karyopherin	karyopherin	NNP
cord-256187-ofp7tupv	111	30	a2	a2	NNP
cord-256187-ofp7tupv	111	31	;	;	:
cord-256187-ofp7tupv	111	32	RchI	RchI	NNP
cord-256187-ofp7tupv	111	33	subfamily	subfamily	NN
cord-256187-ofp7tupv	111	34	)	)	-RRB-
cord-256187-ofp7tupv	111	35	,	,	,
cord-256187-ofp7tupv	111	36	a3	a3	NNP
cord-256187-ofp7tupv	111	37	or	or	CC
cord-256187-ofp7tupv	111	38	a4	a4	NNP
cord-256187-ofp7tupv	111	39	(	(	-LRB-
cord-256187-ofp7tupv	111	40	karyopherin	karyopherin	NNP
cord-256187-ofp7tupv	111	41	a4	a4	NNP
cord-256187-ofp7tupv	111	42	,	,	,
cord-256187-ofp7tupv	111	43	a3	a3	NNP
cord-256187-ofp7tupv	111	44	;	;	:
cord-256187-ofp7tupv	111	45	Qip1	Qip1	NNP
cord-256187-ofp7tupv	111	46	subfamily	subfamily	NN
cord-256187-ofp7tupv	111	47	)	)	-RRB-
cord-256187-ofp7tupv	112	1	(	(	-LRB-
cord-256187-ofp7tupv	112	2	Reid	Reid	NNP
cord-256187-ofp7tupv	112	3	et	et	NNP
cord-256187-ofp7tupv	112	4	al	al	NNP
cord-256187-ofp7tupv	112	5	.	.	NNP
cord-256187-ofp7tupv	112	6	,	,	,
cord-256187-ofp7tupv	112	7	2007	2007	CD
cord-256187-ofp7tupv	112	8	)	)	-RRB-
cord-256187-ofp7tupv	113	1	and	and	CC
cord-256187-ofp7tupv	113	2	does	do	VBZ
cord-256187-ofp7tupv	113	3	not	not	RB
cord-256187-ofp7tupv	113	4	affect	affect	VB
cord-256187-ofp7tupv	113	5	nuclear	nuclear	JJ
cord-256187-ofp7tupv	113	6	import	import	NN
cord-256187-ofp7tupv	113	7	mediated	mediate	VBN
cord-256187-ofp7tupv	113	8	by	by	IN
cord-256187-ofp7tupv	113	9	these	these	DT
cord-256187-ofp7tupv	113	10	factors	factor	NNS
cord-256187-ofp7tupv	113	11	.	.	.
cord-256187-ofp7tupv	114	1	Mutational	mutational	JJ
cord-256187-ofp7tupv	114	2	analyses	analysis	NNS
cord-256187-ofp7tupv	114	3	revealed	reveal	VBD
cord-256187-ofp7tupv	114	4	that	that	IN
cord-256187-ofp7tupv	114	5	VP24	VP24	NNP
cord-256187-ofp7tupv	114	6	binds	bind	VBZ
cord-256187-ofp7tupv	114	7	to	to	IN
cord-256187-ofp7tupv	114	8	amino	amino	JJ
cord-256187-ofp7tupv	114	9	acids	acid	NNS
cord-256187-ofp7tupv	114	10	458	458	CD
cord-256187-ofp7tupv	114	11	-	-	SYM
cord-256187-ofp7tupv	114	12	504	504	CD
cord-256187-ofp7tupv	114	13	in	in	IN
cord-256187-ofp7tupv	114	14	importin	importin	NNP
cord-256187-ofp7tupv	114	15	a5	a5	NNP
cord-256187-ofp7tupv	114	16	,	,	,
cord-256187-ofp7tupv	114	17	which	which	WDT
cord-256187-ofp7tupv	114	18	constitute	constitute	VBP
cord-256187-ofp7tupv	114	19	armadillo	armadillo	NN
cord-256187-ofp7tupv	114	20	repeat	repeat	NN
cord-256187-ofp7tupv	114	21	(	(	-LRB-
cord-256187-ofp7tupv	114	22	ARM	arm	NN
cord-256187-ofp7tupv	114	23	)	)	-RRB-
cord-256187-ofp7tupv	114	24	10	10	CD
cord-256187-ofp7tupv	114	25	and	and	CC
cord-256187-ofp7tupv	114	26	comprise	comprise	VBP
cord-256187-ofp7tupv	114	27	part	part	NN
cord-256187-ofp7tupv	114	28	of	of	IN
cord-256187-ofp7tupv	114	29	the	the	DT
cord-256187-ofp7tupv	114	30	binding	binding	NN
cord-256187-ofp7tupv	114	31	site	site	NN
cord-256187-ofp7tupv	114	32	for	for	IN
cord-256187-ofp7tupv	114	33	PY	py	NN
cord-256187-ofp7tupv	114	34	-	-	HYPH
cord-256187-ofp7tupv	114	35	STAT1	stat1	XX
cord-256187-ofp7tupv	115	1	(	(	-LRB-
cord-256187-ofp7tupv	115	2	Reid	Reid	NNP
cord-256187-ofp7tupv	115	3	et	et	NNP
cord-256187-ofp7tupv	115	4	al	al	NNP
cord-256187-ofp7tupv	115	5	.	.	NNP
cord-256187-ofp7tupv	115	6	,	,	,
cord-256187-ofp7tupv	115	7	2006	2006	CD
cord-256187-ofp7tupv	116	1	(	(	-LRB-
cord-256187-ofp7tupv	116	2	Reid	Reid	NNP
cord-256187-ofp7tupv	116	3	et	et	NNP
cord-256187-ofp7tupv	116	4	al	al	NNP
cord-256187-ofp7tupv	116	5	.	.	NNP
cord-256187-ofp7tupv	116	6	,	,	,
cord-256187-ofp7tupv	116	7	,	,	,
cord-256187-ofp7tupv	116	8	2007	2007	CD
cord-256187-ofp7tupv	116	9	.	.	.
cord-256187-ofp7tupv	117	1	Predictions	prediction	NNS
cord-256187-ofp7tupv	117	2	on	on	IN
cord-256187-ofp7tupv	117	3	VP24	VP24	NNP
cord-256187-ofp7tupv	117	4	structure	structure	NN
cord-256187-ofp7tupv	117	5	offer	offer	VBP
cord-256187-ofp7tupv	117	6	insights	insight	NNS
cord-256187-ofp7tupv	117	7	into	into	IN
cord-256187-ofp7tupv	117	8	the	the	DT
cord-256187-ofp7tupv	117	9	mechanisms	mechanism	NNS
cord-256187-ofp7tupv	117	10	potentially	potentially	RB
cord-256187-ofp7tupv	117	11	underlying	underlie	VBG
cord-256187-ofp7tupv	117	12	VP24	VP24	NNP
cord-256187-ofp7tupv	117	13	inhibition	inhibition	NN
cord-256187-ofp7tupv	117	14	of	of	IN
cord-256187-ofp7tupv	117	15	importin	importin	NNP
cord-256187-ofp7tupv	117	16	a.	a.	NN
cord-256187-ofp7tupv	117	17	)	)	-RRB-
cord-256187-ofp7tupv	117	18	.	.	.
cord-256187-ofp7tupv	118	1	Thus	thus	RB
cord-256187-ofp7tupv	118	2	,	,	,
cord-256187-ofp7tupv	118	3	it	-PRON-	PRP
cord-256187-ofp7tupv	118	4	was	be	VBD
cord-256187-ofp7tupv	118	5	suggested	suggest	VBN
cord-256187-ofp7tupv	118	6	that	that	IN
cord-256187-ofp7tupv	118	7	VP24	VP24	NNP
cord-256187-ofp7tupv	118	8	,	,	,
cord-256187-ofp7tupv	118	9	like	like	IN
cord-256187-ofp7tupv	118	10	importin	importin	NNP
cord-256187-ofp7tupv	118	11	a	a	DT
cord-256187-ofp7tupv	118	12	,	,	,
cord-256187-ofp7tupv	118	13	importin	importin	NNP
cord-256187-ofp7tupv	118	14	b	b	NNP
cord-256187-ofp7tupv	118	15	and	and	CC
cord-256187-ofp7tupv	118	16	exportins	exportins	NNP
cord-256187-ofp7tupv	118	17	(	(	-LRB-
cord-256187-ofp7tupv	118	18	nuclear	nuclear	JJ
cord-256187-ofp7tupv	118	19	export	export	NN
cord-256187-ofp7tupv	118	20	factors	factor	NNS
cord-256187-ofp7tupv	118	21	important	important	JJ
cord-256187-ofp7tupv	118	22	for	for	IN
cord-256187-ofp7tupv	118	23	recycling	recycling	NN
cord-256187-ofp7tupv	118	24	of	of	IN
cord-256187-ofp7tupv	118	25	importin	importin	NN
cord-256187-ofp7tupv	119	1	a	a	DT
cord-256187-ofp7tupv	119	2	to	to	IN
cord-256187-ofp7tupv	119	3	the	the	DT
cord-256187-ofp7tupv	119	4	cytoplasm	cytoplasm	NN
cord-256187-ofp7tupv	119	5	)	)	-RRB-
cord-256187-ofp7tupv	119	6	,	,	,
cord-256187-ofp7tupv	119	7	belongs	belong	VBZ
cord-256187-ofp7tupv	119	8	to	to	IN
cord-256187-ofp7tupv	119	9	the	the	DT
cord-256187-ofp7tupv	119	10	ARM	ARM	NNP
cord-256187-ofp7tupv	119	11	family	family	NN
cord-256187-ofp7tupv	119	12	of	of	IN
cord-256187-ofp7tupv	119	13	proteins	protein	NNS
cord-256187-ofp7tupv	119	14	.	.	.
cord-256187-ofp7tupv	120	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	120	2	,	,	,
cord-256187-ofp7tupv	120	3	it	-PRON-	PRP
cord-256187-ofp7tupv	120	4	was	be	VBD
cord-256187-ofp7tupv	120	5	posited	posit	VBN
cord-256187-ofp7tupv	120	6	that	that	IN
cord-256187-ofp7tupv	120	7	binding	binding	NN
cord-256187-ofp7tupv	120	8	of	of	IN
cord-256187-ofp7tupv	120	9	VP24	VP24	NNP
cord-256187-ofp7tupv	120	10	to	to	IN
cord-256187-ofp7tupv	120	11	importin	importin	NNP
cord-256187-ofp7tupv	120	12	a	a	DT
cord-256187-ofp7tupv	120	13	mimics	mimic	NNS
cord-256187-ofp7tupv	120	14	that	that	WDT
cord-256187-ofp7tupv	120	15	of	of	IN
cord-256187-ofp7tupv	120	16	exportin	exportin	NNP
cord-256187-ofp7tupv	120	17	,	,	,
cord-256187-ofp7tupv	120	18	which	which	WDT
cord-256187-ofp7tupv	120	19	also	also	RB
cord-256187-ofp7tupv	120	20	targets	target	VBZ
cord-256187-ofp7tupv	120	21	ARM	arm	NN
cord-256187-ofp7tupv	120	22	repeat	repeat	NN
cord-256187-ofp7tupv	120	23	10	10	CD
cord-256187-ofp7tupv	120	24	.	.	.
cord-256187-ofp7tupv	121	1	As	as	IN
cord-256187-ofp7tupv	121	2	a	a	DT
cord-256187-ofp7tupv	121	3	consequence	consequence	NN
cord-256187-ofp7tupv	121	4	,	,	,
cord-256187-ofp7tupv	121	5	VP24	VP24	NNP
cord-256187-ofp7tupv	121	6	may	may	MD
cord-256187-ofp7tupv	121	7	block	block	VB
cord-256187-ofp7tupv	121	8	release	release	NN
cord-256187-ofp7tupv	121	9	of	of	IN
cord-256187-ofp7tupv	121	10	the	the	DT
cord-256187-ofp7tupv	121	11	autoinhibitory	autoinhibitory	JJ
cord-256187-ofp7tupv	121	12	NLS	NLS	NNP
cord-256187-ofp7tupv	121	13	of	of	IN
cord-256187-ofp7tupv	121	14	importin	importin	NNP
cord-256187-ofp7tupv	121	15	a	a	DT
cord-256187-ofp7tupv	121	16	,	,	,
cord-256187-ofp7tupv	121	17	and	and	CC
cord-256187-ofp7tupv	121	18	this	this	DT
cord-256187-ofp7tupv	121	19	would	would	MD
cord-256187-ofp7tupv	121	20	inhibit	inhibit	VB
cord-256187-ofp7tupv	121	21	binding	bind	VBG
cord-256187-ofp7tupv	121	22	of	of	IN
cord-256187-ofp7tupv	121	23	other	other	JJ
cord-256187-ofp7tupv	121	24	proteins	protein	NNS
cord-256187-ofp7tupv	121	25	to	to	IN
cord-256187-ofp7tupv	121	26	the	the	DT
cord-256187-ofp7tupv	121	27	NLS	NLS	NNP
cord-256187-ofp7tupv	121	28	binding	binding	NN
cord-256187-ofp7tupv	121	29	site	site	NN
cord-256187-ofp7tupv	121	30	of	of	IN
cord-256187-ofp7tupv	121	31	importin	importin	NNP
cord-256187-ofp7tupv	121	32	a	a	DT
cord-256187-ofp7tupv	121	33	,	,	,
cord-256187-ofp7tupv	121	34	including	include	VBG
cord-256187-ofp7tupv	121	35	PY	py	NN
cord-256187-ofp7tupv	121	36	-	-	HYPH
cord-256187-ofp7tupv	121	37	STAT1	stat1	NN
cord-256187-ofp7tupv	121	38	.	.	.
cord-256187-ofp7tupv	122	1	Alternatively	alternatively	RB
cord-256187-ofp7tupv	122	2	,	,	,
cord-256187-ofp7tupv	122	3	targeting	target	VBG
cord-256187-ofp7tupv	122	4	the	the	DT
cord-256187-ofp7tupv	122	5	ARM10	ARM10	NNP
cord-256187-ofp7tupv	122	6	repeat	repeat	NN
cord-256187-ofp7tupv	122	7	of	of	IN
cord-256187-ofp7tupv	122	8	importin	importin	NN
cord-256187-ofp7tupv	122	9	a	a	DT
cord-256187-ofp7tupv	122	10	by	by	IN
cord-256187-ofp7tupv	122	11	VP24	VP24	NNP
cord-256187-ofp7tupv	122	12	may	may	MD
cord-256187-ofp7tupv	122	13	block	block	VB
cord-256187-ofp7tupv	122	14	binding	binding	NN
cord-256187-ofp7tupv	122	15	of	of	IN
cord-256187-ofp7tupv	122	16	PY	py	NN
cord-256187-ofp7tupv	122	17	-	-	HYPH
cord-256187-ofp7tupv	122	18	STAT1	stat1	NN
cord-256187-ofp7tupv	122	19	because	because	IN
cord-256187-ofp7tupv	122	20	of	of	IN
cord-256187-ofp7tupv	122	21	competitive	competitive	JJ
cord-256187-ofp7tupv	122	22	inhibition	inhibition	NN
cord-256187-ofp7tupv	122	23	.	.	.
cord-256187-ofp7tupv	123	1	In	in	IN
cord-256187-ofp7tupv	123	2	VP24	VP24	NNP
cord-256187-ofp7tupv	123	3	,	,	,
cord-256187-ofp7tupv	123	4	the	the	DT
cord-256187-ofp7tupv	123	5	amino	amino	NN
cord-256187-ofp7tupv	123	6	acid	acid	NN
cord-256187-ofp7tupv	123	7	residues	residue	NNS
cord-256187-ofp7tupv	123	8	42	42	CD
cord-256187-ofp7tupv	123	9	and	and	CC
cord-256187-ofp7tupv	123	10	142	142	CD
cord-256187-ofp7tupv	123	11	-	-	SYM
cord-256187-ofp7tupv	123	12	146	146	CD
cord-256187-ofp7tupv	123	13	were	be	VBD
cord-256187-ofp7tupv	123	14	found	find	VBN
cord-256187-ofp7tupv	123	15	to	to	TO
cord-256187-ofp7tupv	123	16	be	be	VB
cord-256187-ofp7tupv	123	17	crucial	crucial	JJ
cord-256187-ofp7tupv	123	18	for	for	IN
cord-256187-ofp7tupv	123	19	the	the	DT
cord-256187-ofp7tupv	123	20	inhibition	inhibition	NN
cord-256187-ofp7tupv	123	21	of	of	IN
cord-256187-ofp7tupv	123	22	IFN	IFN	NNP
cord-256187-ofp7tupv	123	23	-	-	HYPH
cord-256187-ofp7tupv	123	24	b	b	NN
cord-256187-ofp7tupv	123	25	-	-	HYPH
cord-256187-ofp7tupv	123	26	induced	induce	VBN
cord-256187-ofp7tupv	123	27	signalling	signalling	NN
cord-256187-ofp7tupv	123	28	and	and	CC
cord-256187-ofp7tupv	123	29	PY	py	NN
cord-256187-ofp7tupv	123	30	-	-	HYPH
cord-256187-ofp7tupv	123	31	STAT	stat	NN
cord-256187-ofp7tupv	123	32	accumulation	accumulation	NN
cord-256187-ofp7tupv	123	33	in	in	IN
cord-256187-ofp7tupv	123	34	the	the	DT
cord-256187-ofp7tupv	123	35	nucleus	nucleus	NN
cord-256187-ofp7tupv	124	1	(	(	-LRB-
cord-256187-ofp7tupv	124	2	Mateo	Mateo	NNP
cord-256187-ofp7tupv	124	3	et	et	NNP
cord-256187-ofp7tupv	124	4	al	al	NNP
cord-256187-ofp7tupv	124	5	.	.	NNP
cord-256187-ofp7tupv	124	6	,	,	,
cord-256187-ofp7tupv	124	7	2010	2010	CD
cord-256187-ofp7tupv	124	8	)	)	-RRB-
cord-256187-ofp7tupv	124	9	.	.	.
cord-256187-ofp7tupv	125	1	The	the	DT
cord-256187-ofp7tupv	125	2	lack	lack	NN
cord-256187-ofp7tupv	125	3	of	of	IN
cord-256187-ofp7tupv	125	4	inhibition	inhibition	NN
cord-256187-ofp7tupv	125	5	of	of	IN
cord-256187-ofp7tupv	125	6	IFN	IFN	NNP
cord-256187-ofp7tupv	125	7	-	-	HYPH
cord-256187-ofp7tupv	125	8	b	b	NN
cord-256187-ofp7tupv	125	9	-	-	HYPH
cord-256187-ofp7tupv	125	10	induced	induce	VBN
cord-256187-ofp7tupv	125	11	signalling	signal	VBG
cord-256187-ofp7tupv	125	12	by	by	IN
cord-256187-ofp7tupv	125	13	a	a	DT
cord-256187-ofp7tupv	125	14	VP24	VP24	NNP
cord-256187-ofp7tupv	125	15	mutant	mutant	NN
cord-256187-ofp7tupv	125	16	with	with	IN
cord-256187-ofp7tupv	125	17	amino	amino	JJ
cord-256187-ofp7tupv	125	18	acid	acid	NN
cord-256187-ofp7tupv	125	19	exchanges	exchange	NNS
cord-256187-ofp7tupv	125	20	at	at	IN
cord-256187-ofp7tupv	125	21	these	these	DT
cord-256187-ofp7tupv	125	22	positions	position	NNS
cord-256187-ofp7tupv	125	23	correlated	correlate	VBN
cord-256187-ofp7tupv	125	24	with	with	IN
cord-256187-ofp7tupv	125	25	absence	absence	NN
cord-256187-ofp7tupv	125	26	of	of	IN
cord-256187-ofp7tupv	125	27	importin	importin	NNP
cord-256187-ofp7tupv	125	28	a5	a5	NN
cord-256187-ofp7tupv	125	29	binding	binding	NN
cord-256187-ofp7tupv	125	30	,	,	,
cord-256187-ofp7tupv	125	31	highlighting	highlight	VBG
cord-256187-ofp7tupv	125	32	that	that	IN
cord-256187-ofp7tupv	125	33	binding	binding	NN
cord-256187-ofp7tupv	125	34	of	of	IN
cord-256187-ofp7tupv	125	35	VP24	VP24	NNP
cord-256187-ofp7tupv	125	36	to	to	IN
cord-256187-ofp7tupv	125	37	importin	importin	NNP
cord-256187-ofp7tupv	125	38	a5	a5	NNP
cord-256187-ofp7tupv	125	39	is	be	VBZ
cord-256187-ofp7tupv	125	40	essential	essential	JJ
cord-256187-ofp7tupv	125	41	for	for	IN
cord-256187-ofp7tupv	125	42	IFN	IFN	NNP
cord-256187-ofp7tupv	125	43	antagonism	antagonism	NN
cord-256187-ofp7tupv	125	44	(	(	-LRB-
cord-256187-ofp7tupv	125	45	Mateo	Mateo	NNP
cord-256187-ofp7tupv	125	46	et	et	NNP
cord-256187-ofp7tupv	125	47	al	al	NNP
cord-256187-ofp7tupv	125	48	.	.	NNP
cord-256187-ofp7tupv	125	49	,	,	,
cord-256187-ofp7tupv	125	50	2010	2010	CD
cord-256187-ofp7tupv	125	51	)	)	-RRB-
cord-256187-ofp7tupv	125	52	.	.	.
cord-256187-ofp7tupv	126	1	The	the	DT
cord-256187-ofp7tupv	126	2	IFN	IFN	NNP
cord-256187-ofp7tupv	126	3	system	system	NN
cord-256187-ofp7tupv	126	4	can	can	MD
cord-256187-ofp7tupv	126	5	protect	protect	VB
cord-256187-ofp7tupv	126	6	immune	immune	JJ
cord-256187-ofp7tupv	126	7	-	-	HYPH
cord-256187-ofp7tupv	126	8	competent	competent	JJ
cord-256187-ofp7tupv	126	9	mice	mouse	NNS
cord-256187-ofp7tupv	126	10	from	from	IN
cord-256187-ofp7tupv	126	11	lethal	lethal	JJ
cord-256187-ofp7tupv	126	12	EBOV	EBOV	NNP
cord-256187-ofp7tupv	126	13	infection	infection	NN
cord-256187-ofp7tupv	127	1	(	(	-LRB-
cord-256187-ofp7tupv	127	2	Bray	Bray	NNP
cord-256187-ofp7tupv	127	3	,	,	,
cord-256187-ofp7tupv	127	4	2001	2001	CD
cord-256187-ofp7tupv	127	5	;	;	:
cord-256187-ofp7tupv	128	1	Mahanty	Mahanty	NNP
cord-256187-ofp7tupv	128	2	et	et	FW
cord-256187-ofp7tupv	128	3	al	al	NNP
cord-256187-ofp7tupv	128	4	.	.	NNP
cord-256187-ofp7tupv	128	5	,	,	,
cord-256187-ofp7tupv	128	6	2003	2003	CD
cord-256187-ofp7tupv	128	7	)	)	-RRB-
cord-256187-ofp7tupv	128	8	.	.	.
cord-256187-ofp7tupv	129	1	Adaptation	adaptation	NN
cord-256187-ofp7tupv	129	2	of	of	IN
cord-256187-ofp7tupv	129	3	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	129	4	to	to	IN
cord-256187-ofp7tupv	129	5	lethal	lethal	JJ
cord-256187-ofp7tupv	129	6	infection	infection	NN
cord-256187-ofp7tupv	129	7	of	of	IN
cord-256187-ofp7tupv	129	8	mice	mouse	NNS
cord-256187-ofp7tupv	129	9	was	be	VBD
cord-256187-ofp7tupv	129	10	associated	associate	VBN
cord-256187-ofp7tupv	129	11	with	with	IN
cord-256187-ofp7tupv	129	12	mutations	mutation	NNS
cord-256187-ofp7tupv	129	13	in	in	IN
cord-256187-ofp7tupv	129	14	VP24	VP24	NNP
cord-256187-ofp7tupv	129	15	and	and	CC
cord-256187-ofp7tupv	129	16	NP	NP	NNP
cord-256187-ofp7tupv	129	17	.	.	.
cord-256187-ofp7tupv	130	1	However	however	RB
cord-256187-ofp7tupv	130	2	,	,	,
cord-256187-ofp7tupv	130	3	both	both	DT
cord-256187-ofp7tupv	130	4	wild	wild	JJ
cord-256187-ofp7tupv	130	5	-	-	HYPH
cord-256187-ofp7tupv	130	6	type	type	NN
cord-256187-ofp7tupv	130	7	VP24	VP24	NNP
cord-256187-ofp7tupv	130	8	and	and	CC
cord-256187-ofp7tupv	130	9	VP24	VP24	NNP
cord-256187-ofp7tupv	130	10	of	of	IN
cord-256187-ofp7tupv	130	11	the	the	DT
cord-256187-ofp7tupv	130	12	mouse	mouse	NN
cord-256187-ofp7tupv	130	13	-	-	HYPH
cord-256187-ofp7tupv	130	14	adapted	adapt	VBN
cord-256187-ofp7tupv	130	15	(	(	-LRB-
cord-256187-ofp7tupv	130	16	MA	MA	NNP
cord-256187-ofp7tupv	130	17	)	)	-RRB-
cord-256187-ofp7tupv	130	18	strain	strain	NN
cord-256187-ofp7tupv	130	19	were	be	VBD
cord-256187-ofp7tupv	130	20	able	able	JJ
cord-256187-ofp7tupv	130	21	to	to	TO
cord-256187-ofp7tupv	130	22	bind	bind	VB
cord-256187-ofp7tupv	130	23	to	to	IN
cord-256187-ofp7tupv	130	24	human	human	JJ
cord-256187-ofp7tupv	130	25	and	and	CC
cord-256187-ofp7tupv	130	26	mouse	mouse	NN
cord-256187-ofp7tupv	130	27	NP-1	NP-1	NNP
cord-256187-ofp7tupv	130	28	importins	importin	NNS
cord-256187-ofp7tupv	130	29	and	and	CC
cord-256187-ofp7tupv	130	30	to	to	TO
cord-256187-ofp7tupv	130	31	disrupt	disrupt	VB
cord-256187-ofp7tupv	130	32	the	the	DT
cord-256187-ofp7tupv	130	33	interaction	interaction	NN
cord-256187-ofp7tupv	130	34	with	with	IN
cord-256187-ofp7tupv	130	35	PY	py	NN
cord-256187-ofp7tupv	130	36	-	-	HYPH
cord-256187-ofp7tupv	130	37	STAT1	stat1	XX
cord-256187-ofp7tupv	131	1	(	(	-LRB-
cord-256187-ofp7tupv	131	2	Reid	Reid	NNP
cord-256187-ofp7tupv	131	3	et	et	NNP
cord-256187-ofp7tupv	131	4	al	al	NNP
cord-256187-ofp7tupv	131	5	.	.	NNP
cord-256187-ofp7tupv	131	6	,	,	,
cord-256187-ofp7tupv	131	7	2007	2007	CD
cord-256187-ofp7tupv	131	8	)	)	-RRB-
cord-256187-ofp7tupv	131	9	.	.	.
cord-256187-ofp7tupv	132	1	Similar	similar	JJ
cord-256187-ofp7tupv	132	2	findings	finding	NNS
cord-256187-ofp7tupv	132	3	were	be	VBD
cord-256187-ofp7tupv	132	4	documented	document	VBN
cord-256187-ofp7tupv	132	5	for	for	IN
cord-256187-ofp7tupv	132	6	VP24	VP24	NNP
cord-256187-ofp7tupv	132	7	of	of	IN
cord-256187-ofp7tupv	132	8	REBOV	REBOV	NNP
cord-256187-ofp7tupv	132	9	,	,	,
cord-256187-ofp7tupv	132	10	which	which	WDT
cord-256187-ofp7tupv	132	11	is	be	VBZ
cord-256187-ofp7tupv	132	12	believed	believe	VBN
cord-256187-ofp7tupv	132	13	to	to	TO
cord-256187-ofp7tupv	132	14	be	be	VB
cord-256187-ofp7tupv	132	15	non	non	JJ
cord-256187-ofp7tupv	132	16	-	-	JJ
cord-256187-ofp7tupv	132	17	pathogenic	pathogenic	JJ
cord-256187-ofp7tupv	132	18	for	for	IN
cord-256187-ofp7tupv	132	19	humans	human	NNS
cord-256187-ofp7tupv	132	20	,	,	,
cord-256187-ofp7tupv	132	21	and	and	CC
cord-256187-ofp7tupv	132	22	it	-PRON-	PRP
cord-256187-ofp7tupv	132	23	was	be	VBD
cord-256187-ofp7tupv	132	24	shown	show	VBN
cord-256187-ofp7tupv	132	25	that	that	IN
cord-256187-ofp7tupv	132	26	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	132	27	,	,	,
cord-256187-ofp7tupv	132	28	REBOV	REBOV	NNP
cord-256187-ofp7tupv	132	29	and	and	CC
cord-256187-ofp7tupv	132	30	MA	MA	NNP
cord-256187-ofp7tupv	132	31	VP24	VP24	NNP
cord-256187-ofp7tupv	132	32	can	can	MD
cord-256187-ofp7tupv	132	33	suppress	suppress	VB
cord-256187-ofp7tupv	132	34	IFN	IFN	NNP
cord-256187-ofp7tupv	132	35	-	-	HYPH
cord-256187-ofp7tupv	132	36	b	b	NN
cord-256187-ofp7tupv	132	37	-	-	HYPH
cord-256187-ofp7tupv	132	38	induced	induce	VBN
cord-256187-ofp7tupv	132	39	gene	gene	NN
cord-256187-ofp7tupv	132	40	expression	expression	NN
cord-256187-ofp7tupv	132	41	(	(	-LRB-
cord-256187-ofp7tupv	132	42	Reid	Reid	NNP
cord-256187-ofp7tupv	132	43	et	et	NNP
cord-256187-ofp7tupv	132	44	al	al	NNP
cord-256187-ofp7tupv	132	45	.	.	NNP
cord-256187-ofp7tupv	132	46	,	,	,
cord-256187-ofp7tupv	132	47	2007	2007	CD
cord-256187-ofp7tupv	132	48	)	)	-RRB-
cord-256187-ofp7tupv	132	49	.	.	.
cord-256187-ofp7tupv	133	1	Thus	thus	RB
cord-256187-ofp7tupv	133	2	,	,	,
cord-256187-ofp7tupv	133	3	alterations	alteration	NNS
cord-256187-ofp7tupv	133	4	in	in	IN
cord-256187-ofp7tupv	133	5	VP24	VP24	NNP
cord-256187-ofp7tupv	133	6	interference	interference	NN
cord-256187-ofp7tupv	133	7	with	with	IN
cord-256187-ofp7tupv	133	8	the	the	DT
cord-256187-ofp7tupv	133	9	IFN	IFN	NNP
cord-256187-ofp7tupv	133	10	response	response	NN
cord-256187-ofp7tupv	133	11	might	may	MD
cord-256187-ofp7tupv	133	12	not	not	RB
cord-256187-ofp7tupv	133	13	account	account	VB
cord-256187-ofp7tupv	133	14	for	for	IN
cord-256187-ofp7tupv	133	15	the	the	DT
cord-256187-ofp7tupv	133	16	acquisition	acquisition	NN
cord-256187-ofp7tupv	133	17	of	of	IN
cord-256187-ofp7tupv	133	18	virulence	virulence	NN
cord-256187-ofp7tupv	133	19	of	of	IN
cord-256187-ofp7tupv	133	20	MA	MA	NNP
cord-256187-ofp7tupv	133	21	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	133	22	in	in	IN
cord-256187-ofp7tupv	133	23	mice	mouse	NNS
cord-256187-ofp7tupv	133	24	and	and	CC
cord-256187-ofp7tupv	133	25	for	for	IN
cord-256187-ofp7tupv	133	26	the	the	DT
cord-256187-ofp7tupv	133	27	lack	lack	NN
cord-256187-ofp7tupv	133	28	of	of	IN
cord-256187-ofp7tupv	133	29	virulence	virulence	NN
cord-256187-ofp7tupv	133	30	of	of	IN
cord-256187-ofp7tupv	133	31	REBOV	REBOV	NNP
cord-256187-ofp7tupv	133	32	in	in	IN
cord-256187-ofp7tupv	133	33	humans	human	NNS
cord-256187-ofp7tupv	133	34	,	,	,
cord-256187-ofp7tupv	133	35	respectively	respectively	RB
cord-256187-ofp7tupv	133	36	.	.	.
cord-256187-ofp7tupv	134	1	The	the	DT
cord-256187-ofp7tupv	134	2	EBOV	EBOV	NNP
cord-256187-ofp7tupv	134	3	-	-	HYPH
cord-256187-ofp7tupv	134	4	encoded	encode	VBN
cord-256187-ofp7tupv	134	5	protein	protein	NN
cord-256187-ofp7tupv	134	6	VP35	VP35	NNP
cord-256187-ofp7tupv	134	7	fulfils	fulfil	VBZ
cord-256187-ofp7tupv	134	8	several	several	JJ
cord-256187-ofp7tupv	134	9	functions	function	NNS
cord-256187-ofp7tupv	134	10	important	important	JJ
cord-256187-ofp7tupv	134	11	for	for	IN
cord-256187-ofp7tupv	134	12	viral	viral	JJ
cord-256187-ofp7tupv	134	13	amplification	amplification	NN
cord-256187-ofp7tupv	134	14	.	.	.
cord-256187-ofp7tupv	135	1	As	as	IN
cord-256187-ofp7tupv	135	2	essential	essential	JJ
cord-256187-ofp7tupv	135	3	polymerase	polymerase	NN
cord-256187-ofp7tupv	135	4	cofactor	cofactor	NN
cord-256187-ofp7tupv	135	5	,	,	,
cord-256187-ofp7tupv	135	6	VP35	VP35	NNP
cord-256187-ofp7tupv	135	7	is	be	VBZ
cord-256187-ofp7tupv	135	8	involved	involve	VBN
cord-256187-ofp7tupv	135	9	in	in	IN
cord-256187-ofp7tupv	135	10	the	the	DT
cord-256187-ofp7tupv	135	11	formation	formation	NN
cord-256187-ofp7tupv	135	12	of	of	IN
cord-256187-ofp7tupv	135	13	the	the	DT
cord-256187-ofp7tupv	135	14	EBOV	EBOV	NNP
cord-256187-ofp7tupv	135	15	RNP	RNP	NNP
cord-256187-ofp7tupv	135	16	complex	complex	NN
cord-256187-ofp7tupv	135	17	and	and	CC
cord-256187-ofp7tupv	135	18	therefore	therefore	RB
cord-256187-ofp7tupv	135	19	crucial	crucial	JJ
cord-256187-ofp7tupv	135	20	for	for	IN
cord-256187-ofp7tupv	135	21	transcription	transcription	NN
cord-256187-ofp7tupv	135	22	and	and	CC
cord-256187-ofp7tupv	135	23	viral	viral	JJ
cord-256187-ofp7tupv	135	24	replication	replication	NN
cord-256187-ofp7tupv	136	1	(	(	-LRB-
cord-256187-ofp7tupv	136	2	Mühlberger	Mühlberger	NNP
cord-256187-ofp7tupv	136	3	et	et	NNP
cord-256187-ofp7tupv	136	4	al	al	NNP
cord-256187-ofp7tupv	136	5	.	.	NNP
cord-256187-ofp7tupv	136	6	,	,	,
cord-256187-ofp7tupv	136	7	1999	1999	CD
cord-256187-ofp7tupv	136	8	)	)	-RRB-
cord-256187-ofp7tupv	136	9	.	.	.
cord-256187-ofp7tupv	137	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	137	2	,	,	,
cord-256187-ofp7tupv	137	3	it	-PRON-	PRP
cord-256187-ofp7tupv	137	4	is	be	VBZ
cord-256187-ofp7tupv	137	5	required	require	VBN
cord-256187-ofp7tupv	137	6	for	for	IN
cord-256187-ofp7tupv	137	7	nucleocapsid	nucleocapsid	NNP
cord-256187-ofp7tupv	137	8	assembly	assembly	NNP
cord-256187-ofp7tupv	137	9	(	(	-LRB-
cord-256187-ofp7tupv	137	10	Huang	Huang	NNP
cord-256187-ofp7tupv	137	11	et	et	NNP
cord-256187-ofp7tupv	137	12	al	al	NNP
cord-256187-ofp7tupv	137	13	.	.	NNP
cord-256187-ofp7tupv	137	14	,	,	,
cord-256187-ofp7tupv	137	15	2002	2002	CD
cord-256187-ofp7tupv	137	16	)	)	-RRB-
cord-256187-ofp7tupv	137	17	.	.	.
cord-256187-ofp7tupv	138	1	Consequently	consequently	RB
cord-256187-ofp7tupv	138	2	,	,	,
cord-256187-ofp7tupv	138	3	interference	interference	NN
cord-256187-ofp7tupv	138	4	with	with	IN
cord-256187-ofp7tupv	138	5	expression	expression	NN
cord-256187-ofp7tupv	138	6	of	of	IN
cord-256187-ofp7tupv	138	7	VP35	VP35	NNP
cord-256187-ofp7tupv	138	8	attenuates	attenuate	VBZ
cord-256187-ofp7tupv	138	9	viral	viral	JJ
cord-256187-ofp7tupv	138	10	growth	growth	NN
cord-256187-ofp7tupv	138	11	and	and	CC
cord-256187-ofp7tupv	138	12	virulence	virulence	NN
cord-256187-ofp7tupv	138	13	(	(	-LRB-
cord-256187-ofp7tupv	138	14	Enterlein	Enterlein	NNP
cord-256187-ofp7tupv	138	15	et	et	FW
cord-256187-ofp7tupv	138	16	al	al	NNP
cord-256187-ofp7tupv	138	17	.	.	NNP
cord-256187-ofp7tupv	138	18	,	,	,
cord-256187-ofp7tupv	138	19	2006	2006	CD
cord-256187-ofp7tupv	138	20	;	;	:
cord-256187-ofp7tupv	138	21	Hartman	Hartman	NNP
cord-256187-ofp7tupv	138	22	et	et	NNP
cord-256187-ofp7tupv	138	23	al	al	NNP
cord-256187-ofp7tupv	138	24	.	.	NNP
cord-256187-ofp7tupv	138	25	,	,	,
cord-256187-ofp7tupv	138	26	2008a	2008a	CD
cord-256187-ofp7tupv	138	27	;	;	:
cord-256187-ofp7tupv	138	28	Prins	Prins	NNP
cord-256187-ofp7tupv	138	29	et	et	NNP
cord-256187-ofp7tupv	138	30	al	al	NNP
cord-256187-ofp7tupv	138	31	.	.	.
cord-256187-ofp7tupv	139	1	,	,	,
cord-256187-ofp7tupv	139	2	2010b	2010b	CD
cord-256187-ofp7tupv	139	3	)	)	-RRB-
cord-256187-ofp7tupv	139	4	.	.	.
cord-256187-ofp7tupv	140	1	Additionally	additionally	RB
cord-256187-ofp7tupv	140	2	,	,	,
cord-256187-ofp7tupv	140	3	VP35	VP35	NNP
cord-256187-ofp7tupv	140	4	blocks	block	VBZ
cord-256187-ofp7tupv	140	5	multiple	multiple	JJ
cord-256187-ofp7tupv	140	6	steps	step	NNS
cord-256187-ofp7tupv	140	7	of	of	IN
cord-256187-ofp7tupv	140	8	the	the	DT
cord-256187-ofp7tupv	140	9	innate	innate	JJ
cord-256187-ofp7tupv	140	10	antiviral	antiviral	JJ
cord-256187-ofp7tupv	140	11	defence	defence	NN
cord-256187-ofp7tupv	140	12	(	(	-LRB-
cord-256187-ofp7tupv	140	13	Fig	Fig	NNP
cord-256187-ofp7tupv	140	14	.	.	NNP
cord-256187-ofp7tupv	140	15	4	4	CD
cord-256187-ofp7tupv	140	16	)	)	-RRB-
cord-256187-ofp7tupv	140	17	,	,	,
cord-256187-ofp7tupv	140	18	such	such	JJ
cord-256187-ofp7tupv	140	19	as	as	IN
cord-256187-ofp7tupv	140	20	the	the	DT
cord-256187-ofp7tupv	140	21	signalling	signal	VBG
cord-256187-ofp7tupv	140	22	pathways	pathway	NNS
cord-256187-ofp7tupv	140	23	leading	lead	VBG
cord-256187-ofp7tupv	140	24	to	to	IN
cord-256187-ofp7tupv	140	25	the	the	DT
cord-256187-ofp7tupv	140	26	expression	expression	NN
cord-256187-ofp7tupv	140	27	of	of	IN
cord-256187-ofp7tupv	140	28	type	type	NN
cord-256187-ofp7tupv	140	29	I	-PRON-	PRP
cord-256187-ofp7tupv	140	30	IFNs	ifns	NN
cord-256187-ofp7tupv	140	31	and	and	CC
cord-256187-ofp7tupv	140	32	type	type	NN
cord-256187-ofp7tupv	141	1	I	-PRON-	PRP
cord-256187-ofp7tupv	141	2	IFN	IFN	NNP
cord-256187-ofp7tupv	141	3	-	-	HYPH
cord-256187-ofp7tupv	141	4	induced	induce	VBN
cord-256187-ofp7tupv	141	5	genes	gene	NNS
cord-256187-ofp7tupv	141	6	,	,	,
cord-256187-ofp7tupv	141	7	double	double	RB
cord-256187-ofp7tupv	141	8	-	-	HYPH
cord-256187-ofp7tupv	141	9	stranded	stranded	JJ
cord-256187-ofp7tupv	141	10	(	(	-LRB-
cord-256187-ofp7tupv	141	11	ds	ds	NNP
cord-256187-ofp7tupv	141	12	)	)	-RRB-
cord-256187-ofp7tupv	141	13	RNA	RNA	NNP
cord-256187-ofp7tupv	141	14	-	-	HYPH
cord-256187-ofp7tupv	141	15	dependent	dependent	JJ
cord-256187-ofp7tupv	141	16	protein	protein	NN
cord-256187-ofp7tupv	141	17	kinase	kinase	NN
cord-256187-ofp7tupv	141	18	(	(	-LRB-
cord-256187-ofp7tupv	141	19	PKR	PKR	NNP
cord-256187-ofp7tupv	141	20	)	)	-RRB-
cord-256187-ofp7tupv	141	21	translation	translation	NN
cord-256187-ofp7tupv	141	22	inhibition	inhibition	NN
cord-256187-ofp7tupv	141	23	and	and	CC
cord-256187-ofp7tupv	141	24	RNA	RNA	NNP
cord-256187-ofp7tupv	141	25	silencing	silence	VBG
cord-256187-ofp7tupv	141	26	Cárdenas	Cárdenas	NNP
cord-256187-ofp7tupv	141	27	et	et	NNP
cord-256187-ofp7tupv	141	28	al	al	NNP
cord-256187-ofp7tupv	141	29	.	.	NNP
cord-256187-ofp7tupv	141	30	,	,	,
cord-256187-ofp7tupv	141	31	2006	2006	CD
cord-256187-ofp7tupv	141	32	;	;	:
cord-256187-ofp7tupv	141	33	Feng	Feng	NNP
cord-256187-ofp7tupv	141	34	et	et	FW
cord-256187-ofp7tupv	141	35	al	al	NNP
cord-256187-ofp7tupv	141	36	.	.	NNP
cord-256187-ofp7tupv	141	37	,	,	,
cord-256187-ofp7tupv	141	38	2007	2007	CD
cord-256187-ofp7tupv	141	39	;	;	:
cord-256187-ofp7tupv	141	40	Haasnoot	Haasnoot	NNP
cord-256187-ofp7tupv	141	41	et	et	NNP
cord-256187-ofp7tupv	141	42	al	al	NNP
cord-256187-ofp7tupv	141	43	.	.	NNP
cord-256187-ofp7tupv	141	44	,	,	,
cord-256187-ofp7tupv	141	45	2007	2007	CD
cord-256187-ofp7tupv	141	46	)	)	-RRB-
cord-256187-ofp7tupv	141	47	.	.	.
cord-256187-ofp7tupv	142	1	The	the	DT
cord-256187-ofp7tupv	142	2	key	key	JJ
cord-256187-ofp7tupv	142	3	role	role	NN
cord-256187-ofp7tupv	142	4	of	of	IN
cord-256187-ofp7tupv	142	5	VP35	VP35	NNP
cord-256187-ofp7tupv	142	6	in	in	IN
cord-256187-ofp7tupv	142	7	the	the	DT
cord-256187-ofp7tupv	142	8	defence	defence	NN
cord-256187-ofp7tupv	142	9	against	against	IN
cord-256187-ofp7tupv	142	10	innate	innate	JJ
cord-256187-ofp7tupv	142	11	immunity	immunity	NN
cord-256187-ofp7tupv	142	12	is	be	VBZ
cord-256187-ofp7tupv	142	13	exemplified	exemplify	VBN
cord-256187-ofp7tupv	142	14	by	by	IN
cord-256187-ofp7tupv	142	15	studies	study	NNS
cord-256187-ofp7tupv	142	16	demonstrating	demonstrate	VBG
cord-256187-ofp7tupv	142	17	that	that	IN
cord-256187-ofp7tupv	142	18	VP35	VP35	NNP
cord-256187-ofp7tupv	142	19	mutated	mutated	JJ
cord-256187-ofp7tupv	142	20	viruses	virus	NNS
cord-256187-ofp7tupv	142	21	are	be	VBP
cord-256187-ofp7tupv	142	22	unable	unable	JJ
cord-256187-ofp7tupv	142	23	to	to	TO
cord-256187-ofp7tupv	142	24	block	block	VB
cord-256187-ofp7tupv	142	25	the	the	DT
cord-256187-ofp7tupv	142	26	IFN	IFN	NNP
cord-256187-ofp7tupv	142	27	-	-	HYPH
cord-256187-ofp7tupv	142	28	dependent	dependent	JJ
cord-256187-ofp7tupv	142	29	induction	induction	NN
cord-256187-ofp7tupv	142	30	of	of	IN
cord-256187-ofp7tupv	142	31	antiviral	antiviral	JJ
cord-256187-ofp7tupv	142	32	factors	factor	NNS
cord-256187-ofp7tupv	142	33	(	(	-LRB-
cord-256187-ofp7tupv	142	34	Cárdenas	Cárdenas	NNP
cord-256187-ofp7tupv	142	35	et	et	NNP
cord-256187-ofp7tupv	142	36	al	al	NNP
cord-256187-ofp7tupv	142	37	.	.	NNP
cord-256187-ofp7tupv	142	38	,	,	,
cord-256187-ofp7tupv	142	39	2006	2006	CD
cord-256187-ofp7tupv	142	40	;	;	.
cord-256187-ofp7tupv	143	1	Hartman	Hartman	NNP
cord-256187-ofp7tupv	143	2	et	et	NNP
cord-256187-ofp7tupv	143	3	al	al	NNP
cord-256187-ofp7tupv	143	4	.	.	NNP
cord-256187-ofp7tupv	143	5	,	,	,
cord-256187-ofp7tupv	143	6	2008a	2008a	CD
cord-256187-ofp7tupv	143	7	,	,	,
cord-256187-ofp7tupv	143	8	b	b	LS
cord-256187-ofp7tupv	143	9	)	)	-RRB-
cord-256187-ofp7tupv	143	10	.	.	.
cord-256187-ofp7tupv	144	1	Moreover	moreover	RB
cord-256187-ofp7tupv	144	2	,	,	,
cord-256187-ofp7tupv	144	3	VP35	VP35	NNP
cord-256187-ofp7tupv	144	4	impairs	impair	VBZ
cord-256187-ofp7tupv	144	5	the	the	DT
cord-256187-ofp7tupv	144	6	maturation	maturation	NN
cord-256187-ofp7tupv	144	7	of	of	IN
cord-256187-ofp7tupv	144	8	dendritic	dendritic	JJ
cord-256187-ofp7tupv	144	9	cells	cell	NNS
cord-256187-ofp7tupv	144	10	and	and	CC
cord-256187-ofp7tupv	144	11	thus	thus	RB
cord-256187-ofp7tupv	144	12	prevents	prevent	VBZ
cord-256187-ofp7tupv	144	13	the	the	DT
cord-256187-ofp7tupv	144	14	establishment	establishment	NN
cord-256187-ofp7tupv	144	15	of	of	IN
cord-256187-ofp7tupv	144	16	an	an	DT
cord-256187-ofp7tupv	144	17	adaptive	adaptive	JJ
cord-256187-ofp7tupv	144	18	immune	immune	JJ
cord-256187-ofp7tupv	144	19	response	response	NN
cord-256187-ofp7tupv	144	20	(	(	-LRB-
cord-256187-ofp7tupv	144	21	Jin	Jin	NNP
cord-256187-ofp7tupv	144	22	et	et	NNP
cord-256187-ofp7tupv	144	23	al	al	NNP
cord-256187-ofp7tupv	144	24	.	.	NNP
cord-256187-ofp7tupv	144	25	,	,	,
cord-256187-ofp7tupv	144	26	2010	2010	CD
cord-256187-ofp7tupv	144	27	)	)	-RRB-
cord-256187-ofp7tupv	144	28	,	,	,
cord-256187-ofp7tupv	144	29	an	an	DT
cord-256187-ofp7tupv	144	30	important	important	JJ
cord-256187-ofp7tupv	144	31	feature	feature	NN
cord-256187-ofp7tupv	144	32	of	of	IN
cord-256187-ofp7tupv	144	33	EBOV	EBOV	NNP
cord-256187-ofp7tupv	144	34	haemorrhagic	haemorrhagic	JJ
cord-256187-ofp7tupv	144	35	fever	fever	NN
cord-256187-ofp7tupv	144	36	pathogenesis	pathogenesis	NN
cord-256187-ofp7tupv	144	37	(	(	-LRB-
cord-256187-ofp7tupv	144	38	Hartman	Hartman	NNP
cord-256187-ofp7tupv	144	39	et	et	NNP
cord-256187-ofp7tupv	144	40	al	al	NNP
cord-256187-ofp7tupv	144	41	.	.	NNP
cord-256187-ofp7tupv	144	42	,	,	,
cord-256187-ofp7tupv	144	43	2008a	2008a	CD
cord-256187-ofp7tupv	144	44	)	)	-RRB-
cord-256187-ofp7tupv	144	45	.	.	.
cord-256187-ofp7tupv	145	1	The	the	DT
cord-256187-ofp7tupv	145	2	ability	ability	NN
cord-256187-ofp7tupv	145	3	of	of	IN
cord-256187-ofp7tupv	145	4	VP35	VP35	NNP
cord-256187-ofp7tupv	145	5	to	to	TO
cord-256187-ofp7tupv	145	6	antagonize	antagonize	VB
cord-256187-ofp7tupv	145	7	the	the	DT
cord-256187-ofp7tupv	145	8	type	type	NN
cord-256187-ofp7tupv	145	9	I	-PRON-	PRP
cord-256187-ofp7tupv	145	10	IFN	IFN	NNP
cord-256187-ofp7tupv	145	11	response	response	NN
cord-256187-ofp7tupv	145	12	was	be	VBD
cord-256187-ofp7tupv	145	13	identified	identify	VBN
cord-256187-ofp7tupv	145	14	by	by	IN
cord-256187-ofp7tupv	145	15	Basler	Basler	NNP
cord-256187-ofp7tupv	145	16	et	et	NNP
cord-256187-ofp7tupv	145	17	al	al	NNP
cord-256187-ofp7tupv	145	18	.	.	.
cord-256187-ofp7tupv	146	1	(	(	-LRB-
cord-256187-ofp7tupv	146	2	2000	2000	CD
cord-256187-ofp7tupv	146	3	)	)	-RRB-
cord-256187-ofp7tupv	146	4	who	who	WP
cord-256187-ofp7tupv	146	5	showed	show	VBD
cord-256187-ofp7tupv	146	6	that	that	IN
cord-256187-ofp7tupv	146	7	VP35	VP35	NNP
cord-256187-ofp7tupv	146	8	can	can	MD
cord-256187-ofp7tupv	146	9	functionally	functionally	RB
cord-256187-ofp7tupv	146	10	replace	replace	VB
cord-256187-ofp7tupv	146	11	the	the	DT
cord-256187-ofp7tupv	146	12	influenza	influenza	NN
cord-256187-ofp7tupv	146	13	A	a	DT
cord-256187-ofp7tupv	146	14	virus	virus	NN
cord-256187-ofp7tupv	146	15	(	(	-LRB-
cord-256187-ofp7tupv	146	16	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	146	17	)	)	-RRB-
cord-256187-ofp7tupv	146	18	non	non	JJ
cord-256187-ofp7tupv	146	19	-	-	JJ
cord-256187-ofp7tupv	146	20	structural	structural	JJ
cord-256187-ofp7tupv	146	21	protein	protein	NN
cord-256187-ofp7tupv	146	22	1	1	CD
cord-256187-ofp7tupv	146	23	(	(	-LRB-
cord-256187-ofp7tupv	146	24	NS1	NS1	NNS
cord-256187-ofp7tupv	146	25	)	)	-RRB-
cord-256187-ofp7tupv	146	26	protein	protein	NN
cord-256187-ofp7tupv	146	27	,	,	,
cord-256187-ofp7tupv	146	28	a	a	DT
cord-256187-ofp7tupv	146	29	viral	viral	JJ
cord-256187-ofp7tupv	146	30	type	type	NN
cord-256187-ofp7tupv	146	31	I	-PRON-	PRP
cord-256187-ofp7tupv	146	32	IFN	IFN	NNP
cord-256187-ofp7tupv	146	33	antagonist	antagonist	NN
cord-256187-ofp7tupv	146	34	.	.	.
cord-256187-ofp7tupv	147	1	VP35	VP35	NNP
cord-256187-ofp7tupv	147	2	was	be	VBD
cord-256187-ofp7tupv	147	3	found	find	VBN
cord-256187-ofp7tupv	147	4	to	to	TO
cord-256187-ofp7tupv	147	5	inhibit	inhibit	VB
cord-256187-ofp7tupv	147	6	the	the	DT
cord-256187-ofp7tupv	147	7	virus	virus	NN
cord-256187-ofp7tupv	147	8	-	-	HYPH
cord-256187-ofp7tupv	147	9	induced	induce	VBN
cord-256187-ofp7tupv	147	10	activation	activation	NN
cord-256187-ofp7tupv	147	11	of	of	IN
cord-256187-ofp7tupv	147	12	type	type	NN
cord-256187-ofp7tupv	147	13	I	-PRON-	PRP
cord-256187-ofp7tupv	147	14	IFN	IFN	NNP
cord-256187-ofp7tupv	147	15	promoters	promoter	NNS
cord-256187-ofp7tupv	147	16	by	by	IN
cord-256187-ofp7tupv	147	17	targeting	target	VBG
cord-256187-ofp7tupv	147	18	the	the	DT
cord-256187-ofp7tupv	147	19	transcription	transcription	NN
cord-256187-ofp7tupv	147	20	factor	factor	NN
cord-256187-ofp7tupv	147	21	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	147	22	.	.	.
cord-256187-ofp7tupv	148	1	In	in	IN
cord-256187-ofp7tupv	148	2	contrast	contrast	NN
cord-256187-ofp7tupv	148	3	,	,	,
cord-256187-ofp7tupv	148	4	activation	activation	NN
cord-256187-ofp7tupv	148	5	of	of	IN
cord-256187-ofp7tupv	148	6	IFN	IFN	NNP
cord-256187-ofp7tupv	148	7	promoters	promoter	NNS
cord-256187-ofp7tupv	148	8	through	through	IN
cord-256187-ofp7tupv	148	9	exogenous	exogenous	JJ
cord-256187-ofp7tupv	148	10	IFN	IFN	NNP
cord-256187-ofp7tupv	148	11	was	be	VBD
cord-256187-ofp7tupv	148	12	not	not	RB
cord-256187-ofp7tupv	148	13	modulated	modulate	VBN
cord-256187-ofp7tupv	148	14	by	by	IN
cord-256187-ofp7tupv	148	15	VP35	VP35	NNP
cord-256187-ofp7tupv	148	16	.	.	.
cord-256187-ofp7tupv	149	1	Upon	upon	IN
cord-256187-ofp7tupv	149	2	activation	activation	NN
cord-256187-ofp7tupv	149	3	by	by	IN
cord-256187-ofp7tupv	149	4	viral	viral	JJ
cord-256187-ofp7tupv	149	5	infection	infection	NN
cord-256187-ofp7tupv	149	6	,	,	,
cord-256187-ofp7tupv	149	7	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	149	8	is	be	VBZ
cord-256187-ofp7tupv	149	9	phosphorylated	phosphorylate	VBN
cord-256187-ofp7tupv	149	10	by	by	IN
cord-256187-ofp7tupv	149	11	cellular	cellular	JJ
cord-256187-ofp7tupv	149	12	kinases	kinase	NNS
cord-256187-ofp7tupv	149	13	such	such	JJ
cord-256187-ofp7tupv	149	14	as	as	IN
cord-256187-ofp7tupv	149	15	TANK	tank	NN
cord-256187-ofp7tupv	149	16	-	-	HYPH
cord-256187-ofp7tupv	149	17	binding	bind	VBG
cord-256187-ofp7tupv	149	18	kinase	kinase	NN
cord-256187-ofp7tupv	149	19	1	1	CD
cord-256187-ofp7tupv	149	20	(	(	-LRB-
cord-256187-ofp7tupv	149	21	TBK-1	TBK-1	NNP
cord-256187-ofp7tupv	149	22	)	)	-RRB-
cord-256187-ofp7tupv	149	23	and	and	CC
cord-256187-ofp7tupv	149	24	IjB	ijb	NN
cord-256187-ofp7tupv	149	25	kinase	kinase	NNP
cord-256187-ofp7tupv	149	26	epsilon	epsilon	NNP
cord-256187-ofp7tupv	149	27	(	(	-LRB-
cord-256187-ofp7tupv	149	28	IKKe	IKKe	NNP
cord-256187-ofp7tupv	149	29	)	)	-RRB-
cord-256187-ofp7tupv	149	30	(	(	-LRB-
cord-256187-ofp7tupv	150	1	Prins	Prins	NNP
cord-256187-ofp7tupv	150	2	et	et	NNP
cord-256187-ofp7tupv	150	3	al	al	NNP
cord-256187-ofp7tupv	150	4	.	.	NNP
cord-256187-ofp7tupv	150	5	,	,	,
cord-256187-ofp7tupv	150	6	2009	2009	CD
cord-256187-ofp7tupv	150	7	)	)	-RRB-
cord-256187-ofp7tupv	150	8	.	.	.
cord-256187-ofp7tupv	151	1	Subsequently	subsequently	RB
cord-256187-ofp7tupv	151	2	,	,	,
cord-256187-ofp7tupv	151	3	IFR-3	ifr-3	IN
cord-256187-ofp7tupv	151	4	dimerizes	dimerizes	NNP
cord-256187-ofp7tupv	151	5	and	and	CC
cord-256187-ofp7tupv	151	6	translocates	translocates	NNPS
cord-256187-ofp7tupv	151	7	into	into	IN
cord-256187-ofp7tupv	151	8	the	the	DT
cord-256187-ofp7tupv	151	9	nucleus	nucleus	NN
cord-256187-ofp7tupv	151	10	where	where	WRB
cord-256187-ofp7tupv	151	11	it	-PRON-	PRP
cord-256187-ofp7tupv	151	12	activates	activate	VBZ
cord-256187-ofp7tupv	151	13	transcription	transcription	NN
cord-256187-ofp7tupv	151	14	of	of	IN
cord-256187-ofp7tupv	151	15	ISGs	ISGs	NNPS
cord-256187-ofp7tupv	151	16	(	(	-LRB-
cord-256187-ofp7tupv	151	17	Fig	Fig	NNP
cord-256187-ofp7tupv	151	18	.	.	NNP
cord-256187-ofp7tupv	151	19	4	4	CD
cord-256187-ofp7tupv	151	20	)	)	-RRB-
cord-256187-ofp7tupv	151	21	.	.	.
cord-256187-ofp7tupv	152	1	VP35	VP35	NNP
cord-256187-ofp7tupv	152	2	blocks	block	VBZ
cord-256187-ofp7tupv	152	3	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	152	4	phosphorylation	phosphorylation	NN
cord-256187-ofp7tupv	152	5	and	and	CC
cord-256187-ofp7tupv	152	6	therefore	therefore	RB
cord-256187-ofp7tupv	152	7	subsequent	subsequent	JJ
cord-256187-ofp7tupv	152	8	nuclear	nuclear	JJ
cord-256187-ofp7tupv	152	9	accumulation	accumulation	NN
cord-256187-ofp7tupv	152	10	of	of	IN
cord-256187-ofp7tupv	152	11	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	152	12	Cárdenas	Cárdenas	NNP
cord-256187-ofp7tupv	152	13	et	et	NNP
cord-256187-ofp7tupv	152	14	al	al	NNP
cord-256187-ofp7tupv	152	15	.	.	NNP
cord-256187-ofp7tupv	152	16	,	,	,
cord-256187-ofp7tupv	152	17	2006	2006	CD
cord-256187-ofp7tupv	152	18	)	)	-RRB-
cord-256187-ofp7tupv	152	19	.	.	.
cord-256187-ofp7tupv	153	1	For	for	IN
cord-256187-ofp7tupv	153	2	this	this	DT
cord-256187-ofp7tupv	153	3	,	,	,
cord-256187-ofp7tupv	153	4	VP35	VP35	NNP
cord-256187-ofp7tupv	153	5	binds	bind	VBZ
cord-256187-ofp7tupv	153	6	to	to	IN
cord-256187-ofp7tupv	153	7	IKKe	IKKe	NNS
cord-256187-ofp7tupv	153	8	and	and	CC
cord-256187-ofp7tupv	153	9	TBK-1	TBK-1	NNP
cord-256187-ofp7tupv	153	10	and	and	CC
cord-256187-ofp7tupv	153	11	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	153	12	substrate	substrate	NN
cord-256187-ofp7tupv	153	13	binding	binding	NN
cord-256187-ofp7tupv	153	14	and	and	CC
cord-256187-ofp7tupv	153	15	kinase	kinase	NN
cord-256187-ofp7tupv	153	16	activity	activity	NN
cord-256187-ofp7tupv	154	1	(	(	-LRB-
cord-256187-ofp7tupv	154	2	Prins	Prins	NNP
cord-256187-ofp7tupv	154	3	et	et	NNP
cord-256187-ofp7tupv	154	4	al	al	NNP
cord-256187-ofp7tupv	154	5	.	.	NNP
cord-256187-ofp7tupv	154	6	,	,	,
cord-256187-ofp7tupv	154	7	2009	2009	CD
cord-256187-ofp7tupv	154	8	)	)	-RRB-
cord-256187-ofp7tupv	154	9	.	.	.
cord-256187-ofp7tupv	155	1	Mutational	Mutational	NNP
cord-256187-ofp7tupv	155	2	studies	study	NNS
cord-256187-ofp7tupv	155	3	revealed	reveal	VBD
cord-256187-ofp7tupv	155	4	that	that	IN
cord-256187-ofp7tupv	155	5	a	a	DT
cord-256187-ofp7tupv	155	6	N	n	CD
cord-256187-ofp7tupv	155	7	-	-	HYPH
cord-256187-ofp7tupv	155	8	terminal	terminal	JJ
cord-256187-ofp7tupv	155	9	coiledcoil	coiledcoil	NNP
cord-256187-ofp7tupv	155	10	domain	domain	NN
cord-256187-ofp7tupv	155	11	in	in	IN
cord-256187-ofp7tupv	155	12	VP35	VP35	NNP
cord-256187-ofp7tupv	155	13	mediates	mediate	VBZ
cord-256187-ofp7tupv	155	14	homooligomerization	homooligomerization	NN
cord-256187-ofp7tupv	155	15	,	,	,
cord-256187-ofp7tupv	155	16	which	which	WDT
cord-256187-ofp7tupv	155	17	was	be	VBD
cord-256187-ofp7tupv	155	18	found	find	VBN
cord-256187-ofp7tupv	155	19	to	to	TO
cord-256187-ofp7tupv	155	20	be	be	VB
cord-256187-ofp7tupv	155	21	essential	essential	JJ
cord-256187-ofp7tupv	155	22	for	for	IN
cord-256187-ofp7tupv	155	23	IFN	IFN	NNP
cord-256187-ofp7tupv	155	24	antagonism	antagonism	NN
cord-256187-ofp7tupv	155	25	exhibited	exhibit	VBN
cord-256187-ofp7tupv	155	26	by	by	IN
cord-256187-ofp7tupv	155	27	the	the	DT
cord-256187-ofp7tupv	155	28	C	C	NNP
cord-256187-ofp7tupv	155	29	-	-	HYPH
cord-256187-ofp7tupv	155	30	terminus	terminus	NN
cord-256187-ofp7tupv	155	31	of	of	IN
cord-256187-ofp7tupv	155	32	the	the	DT
cord-256187-ofp7tupv	155	33	protein	protein	NN
cord-256187-ofp7tupv	155	34	(	(	-LRB-
cord-256187-ofp7tupv	155	35	Reid	Reid	NNP
cord-256187-ofp7tupv	155	36	et	et	NNP
cord-256187-ofp7tupv	155	37	al	al	NNP
cord-256187-ofp7tupv	155	38	.	.	NNP
cord-256187-ofp7tupv	155	39	,	,	,
cord-256187-ofp7tupv	155	40	2005	2005	CD
cord-256187-ofp7tupv	155	41	)	)	-RRB-
cord-256187-ofp7tupv	155	42	.	.	.
cord-256187-ofp7tupv	156	1	Several	several	JJ
cord-256187-ofp7tupv	156	2	amino	amino	NN
cord-256187-ofp7tupv	156	3	acid	acid	NN
cord-256187-ofp7tupv	156	4	residues	residue	NNS
cord-256187-ofp7tupv	156	5	(	(	-LRB-
cord-256187-ofp7tupv	156	6	R305	R305	VBN
cord-256187-ofp7tupv	156	7	,	,	,
cord-256187-ofp7tupv	156	8	K309	K309	NNPS
cord-256187-ofp7tupv	156	9	,	,	,
cord-256187-ofp7tupv	156	10	R312	R312	NNP
cord-256187-ofp7tupv	156	11	,	,	,
cord-256187-ofp7tupv	156	12	K319	K319	NNP
cord-256187-ofp7tupv	156	13	,	,	,
cord-256187-ofp7tupv	156	14	R322	r322	ADD
cord-256187-ofp7tupv	156	15	)	)	-RRB-
cord-256187-ofp7tupv	156	16	in	in	IN
cord-256187-ofp7tupv	156	17	the	the	DT
cord-256187-ofp7tupv	156	18	central	central	JJ
cord-256187-ofp7tupv	156	19	basic	basic	JJ
cord-256187-ofp7tupv	156	20	patch	patch	NN
cord-256187-ofp7tupv	156	21	of	of	IN
cord-256187-ofp7tupv	156	22	the	the	DT
cord-256187-ofp7tupv	156	23	C	C	NNP
cord-256187-ofp7tupv	156	24	-	-	HYPH
cord-256187-ofp7tupv	156	25	terminal	terminal	NN
cord-256187-ofp7tupv	156	26	IFN	IFN	NNP
cord-256187-ofp7tupv	156	27	inhibitory	inhibitory	JJ
cord-256187-ofp7tupv	156	28	domain	domain	NN
cord-256187-ofp7tupv	156	29	(	(	-LRB-
cord-256187-ofp7tupv	156	30	IID	IID	NNP
cord-256187-ofp7tupv	156	31	)	)	-RRB-
cord-256187-ofp7tupv	156	32	of	of	IN
cord-256187-ofp7tupv	156	33	VP35	VP35	NNP
cord-256187-ofp7tupv	156	34	were	be	VBD
cord-256187-ofp7tupv	156	35	shown	show	VBN
cord-256187-ofp7tupv	156	36	to	to	TO
cord-256187-ofp7tupv	156	37	be	be	VB
cord-256187-ofp7tupv	156	38	required	require	VBN
cord-256187-ofp7tupv	156	39	for	for	IN
cord-256187-ofp7tupv	156	40	inhibition	inhibition	NN
cord-256187-ofp7tupv	156	41	of	of	IN
cord-256187-ofp7tupv	156	42	virus	virus	NN
cord-256187-ofp7tupv	156	43	-	-	HYPH
cord-256187-ofp7tupv	156	44	induced	induce	VBN
cord-256187-ofp7tupv	156	45	activation	activation	NN
cord-256187-ofp7tupv	156	46	of	of	IN
cord-256187-ofp7tupv	156	47	IFN	IFN	NNP
cord-256187-ofp7tupv	156	48	-	-	HYPH
cord-256187-ofp7tupv	156	49	regulated	regulate	VBN
cord-256187-ofp7tupv	156	50	promoters	promoter	NNS
cord-256187-ofp7tupv	156	51	and	and	CC
cord-256187-ofp7tupv	156	52	production	production	NN
cord-256187-ofp7tupv	156	53	of	of	IN
cord-256187-ofp7tupv	156	54	IFN	IFN	NNP
cord-256187-ofp7tupv	156	55	-	-	HYPH
cord-256187-ofp7tupv	156	56	b	b	NNP
cord-256187-ofp7tupv	156	57	(	(	-LRB-
cord-256187-ofp7tupv	156	58	Cárdenas	Cárdenas	NNP
cord-256187-ofp7tupv	156	59	et	et	NNP
cord-256187-ofp7tupv	156	60	al	al	NNP
cord-256187-ofp7tupv	156	61	.	.	NNP
cord-256187-ofp7tupv	156	62	,	,	,
cord-256187-ofp7tupv	156	63	2006	2006	CD
cord-256187-ofp7tupv	156	64	;	;	:
cord-256187-ofp7tupv	156	65	Prins	Prins	NNP
cord-256187-ofp7tupv	156	66	et	et	NNP
cord-256187-ofp7tupv	156	67	al	al	NNP
cord-256187-ofp7tupv	156	68	.	.	.
cord-256187-ofp7tupv	157	1	,	,	,
cord-256187-ofp7tupv	157	2	2010b	2010b	CD
cord-256187-ofp7tupv	157	3	)	)	-RRB-
cord-256187-ofp7tupv	157	4	,	,	,
cord-256187-ofp7tupv	157	5	with	with	IN
cord-256187-ofp7tupv	157	6	R312	r312	IN
cord-256187-ofp7tupv	157	7	being	being	NN
cord-256187-ofp7tupv	157	8	of	of	IN
cord-256187-ofp7tupv	157	9	particular	particular	JJ
cord-256187-ofp7tupv	157	10	importance	importance	NN
cord-256187-ofp7tupv	158	1	(	(	-LRB-
cord-256187-ofp7tupv	158	2	Hartman	Hartman	NNP
cord-256187-ofp7tupv	158	3	et	et	NNP
cord-256187-ofp7tupv	158	4	al	al	NNP
cord-256187-ofp7tupv	158	5	.	.	NNP
cord-256187-ofp7tupv	158	6	,	,	,
cord-256187-ofp7tupv	158	7	2004	2004	CD
cord-256187-ofp7tupv	158	8	;	;	:
cord-256187-ofp7tupv	159	1	Cárdenas	Cárdenas	NNP
cord-256187-ofp7tupv	159	2	et	et	NNP
cord-256187-ofp7tupv	159	3	al	al	NNP
cord-256187-ofp7tupv	159	4	.	.	NNP
cord-256187-ofp7tupv	159	5	,	,	,
cord-256187-ofp7tupv	159	6	2006	2006	CD
cord-256187-ofp7tupv	159	7	)	)	-RRB-
cord-256187-ofp7tupv	159	8	.	.	.
cord-256187-ofp7tupv	160	1	Mutations	mutation	NNS
cord-256187-ofp7tupv	160	2	in	in	IN
cord-256187-ofp7tupv	160	3	the	the	DT
cord-256187-ofp7tupv	160	4	IID	IID	NNP
cord-256187-ofp7tupv	160	5	attenuate	attenuate	VB
cord-256187-ofp7tupv	160	6	viral	viral	JJ
cord-256187-ofp7tupv	160	7	growth	growth	NN
cord-256187-ofp7tupv	160	8	in	in	IN
cord-256187-ofp7tupv	160	9	cell	cell	NN
cord-256187-ofp7tupv	160	10	lines	line	NNS
cord-256187-ofp7tupv	160	11	and	and	CC
cord-256187-ofp7tupv	160	12	the	the	DT
cord-256187-ofp7tupv	160	13	C	C	NNP
cord-256187-ofp7tupv	160	14	-	-	HYPH
cord-256187-ofp7tupv	160	15	terminal	terminal	JJ
cord-256187-ofp7tupv	160	16	basic	basic	JJ
cord-256187-ofp7tupv	160	17	patch	patch	NN
cord-256187-ofp7tupv	160	18	residues	residue	NNS
cord-256187-ofp7tupv	160	19	are	be	VBP
cord-256187-ofp7tupv	160	20	highly	highly	RB
cord-256187-ofp7tupv	160	21	conserved	conserve	VBN
cord-256187-ofp7tupv	160	22	between	between	IN
cord-256187-ofp7tupv	160	23	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	160	24	,	,	,
cord-256187-ofp7tupv	160	25	highlighting	highlight	VBG
cord-256187-ofp7tupv	160	26	their	-PRON-	PRP$
cord-256187-ofp7tupv	160	27	importance	importance	NN
cord-256187-ofp7tupv	160	28	for	for	IN
cord-256187-ofp7tupv	160	29	the	the	DT
cord-256187-ofp7tupv	160	30	function	function	NN
cord-256187-ofp7tupv	160	31	of	of	IN
cord-256187-ofp7tupv	160	32	VP35	VP35	NNP
cord-256187-ofp7tupv	160	33	(	(	-LRB-
cord-256187-ofp7tupv	160	34	Hartman	Hartman	NNP
cord-256187-ofp7tupv	160	35	et	et	NNP
cord-256187-ofp7tupv	160	36	al	al	NNP
cord-256187-ofp7tupv	160	37	.	.	NNP
cord-256187-ofp7tupv	160	38	,	,	,
cord-256187-ofp7tupv	160	39	2004	2004	CD
cord-256187-ofp7tupv	160	40	;	;	:
cord-256187-ofp7tupv	160	41	Prins	Prins	NNP
cord-256187-ofp7tupv	160	42	et	et	NNP
cord-256187-ofp7tupv	160	43	al	al	NNP
cord-256187-ofp7tupv	160	44	.	.	NNP
cord-256187-ofp7tupv	160	45	,	,	,
cord-256187-ofp7tupv	160	46	2010b	2010b	CD
cord-256187-ofp7tupv	160	47	)	)	-RRB-
cord-256187-ofp7tupv	160	48	.	.	.
cord-256187-ofp7tupv	161	1	Notably	notably	RB
cord-256187-ofp7tupv	161	2	,	,	,
cord-256187-ofp7tupv	161	3	Fig	Fig	NNP
cord-256187-ofp7tupv	161	4	.	.	NNP
cord-256187-ofp7tupv	161	5	4	4	CD
cord-256187-ofp7tupv	161	6	.	.	.
cord-256187-ofp7tupv	162	1	Interference	interference	NN
cord-256187-ofp7tupv	162	2	of	of	IN
cord-256187-ofp7tupv	162	3	Ebola	Ebola	NNP
cord-256187-ofp7tupv	162	4	virus	virus	NN
cord-256187-ofp7tupv	162	5	VP35	VP35	NNP
cord-256187-ofp7tupv	162	6	with	with	IN
cord-256187-ofp7tupv	162	7	the	the	DT
cord-256187-ofp7tupv	162	8	expression	expression	NN
cord-256187-ofp7tupv	162	9	of	of	IN
cord-256187-ofp7tupv	162	10	IFN	IFN	NNP
cord-256187-ofp7tupv	162	11	and	and	CC
cord-256187-ofp7tupv	162	12	ISGs	ISGs	NNP
cord-256187-ofp7tupv	162	13	.	.	.
cord-256187-ofp7tupv	163	1	Transcription	transcription	NN
cord-256187-ofp7tupv	163	2	of	of	IN
cord-256187-ofp7tupv	163	3	the	the	DT
cord-256187-ofp7tupv	163	4	EBOV	EBOV	NNP
cord-256187-ofp7tupv	163	5	genome	genome	NN
cord-256187-ofp7tupv	163	6	results	result	NNS
cord-256187-ofp7tupv	163	7	in	in	IN
cord-256187-ofp7tupv	163	8	the	the	DT
cord-256187-ofp7tupv	163	9	production	production	NN
cord-256187-ofp7tupv	163	10	of	of	IN
cord-256187-ofp7tupv	163	11	dsRNA	dsrna	NN
cord-256187-ofp7tupv	163	12	intermediates	intermediate	NNS
cord-256187-ofp7tupv	163	13	,	,	,
cord-256187-ofp7tupv	163	14	which	which	WDT
cord-256187-ofp7tupv	163	15	are	be	VBP
cord-256187-ofp7tupv	163	16	recognized	recognize	VBN
cord-256187-ofp7tupv	163	17	by	by	IN
cord-256187-ofp7tupv	163	18	the	the	DT
cord-256187-ofp7tupv	163	19	cytoplasmic	cytoplasmic	JJ
cord-256187-ofp7tupv	163	20	pathogen	pathogen	NN
cord-256187-ofp7tupv	163	21	recognition	recognition	NN
cord-256187-ofp7tupv	163	22	receptor	receptor	NN
cord-256187-ofp7tupv	163	23	(	(	-LRB-
cord-256187-ofp7tupv	163	24	PRR	PRR	NNP
cord-256187-ofp7tupv	163	25	)	)	-RRB-
cord-256187-ofp7tupv	163	26	RIG	rig	NN
cord-256187-ofp7tupv	163	27	-	-	HYPH
cord-256187-ofp7tupv	163	28	I.	I.	NNP
cord-256187-ofp7tupv	163	29	Single	Single	NNP
cord-256187-ofp7tupv	163	30	-	-	HYPH
cord-256187-ofp7tupv	163	31	stranded	strand	VBN
cord-256187-ofp7tupv	163	32	RNA	RNA	NNP
cord-256187-ofp7tupv	163	33	is	be	VBZ
cord-256187-ofp7tupv	163	34	recognized	recognize	VBN
cord-256187-ofp7tupv	163	35	by	by	IN
cord-256187-ofp7tupv	163	36	the	the	DT
cord-256187-ofp7tupv	163	37	endosomal	endosomal	NNP
cord-256187-ofp7tupv	163	38	PRRs	prr	NNS
cord-256187-ofp7tupv	163	39	TLR-7	TLR-7	NNP
cord-256187-ofp7tupv	163	40	and	and	CC
cord-256187-ofp7tupv	163	41	TLR-8	TLR-8	NNPS
cord-256187-ofp7tupv	163	42	.	.	.
cord-256187-ofp7tupv	164	1	Activation	activation	NN
cord-256187-ofp7tupv	164	2	of	of	IN
cord-256187-ofp7tupv	164	3	these	these	DT
cord-256187-ofp7tupv	164	4	PRRs	prr	NNS
cord-256187-ofp7tupv	164	5	induces	induce	VBZ
cord-256187-ofp7tupv	164	6	signalling	signal	VBG
cord-256187-ofp7tupv	164	7	cascades	cascade	NNS
cord-256187-ofp7tupv	164	8	leading	lead	VBG
cord-256187-ofp7tupv	164	9	to	to	IN
cord-256187-ofp7tupv	164	10	the	the	DT
cord-256187-ofp7tupv	164	11	expression	expression	NN
cord-256187-ofp7tupv	164	12	of	of	IN
cord-256187-ofp7tupv	164	13	type	type	NN
cord-256187-ofp7tupv	164	14	I	-PRON-	PRP
cord-256187-ofp7tupv	164	15	IFNs	ifns	VBP
cord-256187-ofp7tupv	164	16	.	.	.
cord-256187-ofp7tupv	165	1	In	in	IN
cord-256187-ofp7tupv	165	2	addition	addition	NN
cord-256187-ofp7tupv	165	3	,	,	,
cord-256187-ofp7tupv	165	4	dsRNA	dsrna	NN
cord-256187-ofp7tupv	165	5	is	be	VBZ
cord-256187-ofp7tupv	165	6	recognized	recognize	VBN
cord-256187-ofp7tupv	165	7	by	by	IN
cord-256187-ofp7tupv	165	8	the	the	DT
cord-256187-ofp7tupv	165	9	RNA	RNA	NNP
cord-256187-ofp7tupv	165	10	interference	interference	NN
cord-256187-ofp7tupv	165	11	machinery	machinery	NN
cord-256187-ofp7tupv	165	12	that	that	WDT
cord-256187-ofp7tupv	165	13	facilitates	facilitate	VBZ
cord-256187-ofp7tupv	165	14	RNA	RNA	NNP
cord-256187-ofp7tupv	165	15	degradation	degradation	NN
cord-256187-ofp7tupv	165	16	and	and	CC
cord-256187-ofp7tupv	165	17	thereby	thereby	RB
cord-256187-ofp7tupv	165	18	suppresses	suppress	VBZ
cord-256187-ofp7tupv	165	19	the	the	DT
cord-256187-ofp7tupv	165	20	expression	expression	NN
cord-256187-ofp7tupv	165	21	of	of	IN
cord-256187-ofp7tupv	165	22	viral	viral	JJ
cord-256187-ofp7tupv	165	23	genes	gene	NNS
cord-256187-ofp7tupv	165	24	.	.	.
cord-256187-ofp7tupv	166	1	VP35	VP35	NNP
cord-256187-ofp7tupv	166	2	is	be	VBZ
cord-256187-ofp7tupv	166	3	able	able	JJ
cord-256187-ofp7tupv	166	4	to	to	TO
cord-256187-ofp7tupv	166	5	block	block	VB
cord-256187-ofp7tupv	166	6	several	several	JJ
cord-256187-ofp7tupv	166	7	of	of	IN
cord-256187-ofp7tupv	166	8	the	the	DT
cord-256187-ofp7tupv	166	9	above	above	RB
cord-256187-ofp7tupv	166	10	-	-	HYPH
cord-256187-ofp7tupv	166	11	described	describe	VBN
cord-256187-ofp7tupv	166	12	processes	process	NNS
cord-256187-ofp7tupv	166	13	.	.	.
cord-256187-ofp7tupv	167	1	Because	because	IN
cord-256187-ofp7tupv	167	2	of	of	IN
cord-256187-ofp7tupv	167	3	its	-PRON-	PRP$
cord-256187-ofp7tupv	167	4	dsRNA	dsrna	JJ
cord-256187-ofp7tupv	167	5	-	-	HYPH
cord-256187-ofp7tupv	167	6	binding	bind	VBG
cord-256187-ofp7tupv	167	7	domain	domain	NN
cord-256187-ofp7tupv	167	8	,	,	,
cord-256187-ofp7tupv	167	9	it	-PRON-	PRP
cord-256187-ofp7tupv	167	10	is	be	VBZ
cord-256187-ofp7tupv	167	11	able	able	JJ
cord-256187-ofp7tupv	167	12	to	to	TO
cord-256187-ofp7tupv	167	13	sequester	sequester	VB
cord-256187-ofp7tupv	167	14	dsRNA	dsrna	NN
cord-256187-ofp7tupv	167	15	from	from	IN
cord-256187-ofp7tupv	167	16	recognition	recognition	NN
cord-256187-ofp7tupv	167	17	by	by	IN
cord-256187-ofp7tupv	167	18	RIG	rig	NN
cord-256187-ofp7tupv	167	19	-	-	:
cord-256187-ofp7tupv	167	20	I	-PRON-	PRP
cord-256187-ofp7tupv	167	21	and	and	CC
cord-256187-ofp7tupv	167	22	to	to	TO
cord-256187-ofp7tupv	167	23	protect	protect	VB
cord-256187-ofp7tupv	167	24	it	-PRON-	PRP
cord-256187-ofp7tupv	167	25	from	from	IN
cord-256187-ofp7tupv	167	26	degradation	degradation	NN
cord-256187-ofp7tupv	167	27	through	through	IN
cord-256187-ofp7tupv	167	28	the	the	DT
cord-256187-ofp7tupv	167	29	RNA	RNA	NNP
cord-256187-ofp7tupv	167	30	-	-	HYPH
cord-256187-ofp7tupv	167	31	induced	induce	VBN
cord-256187-ofp7tupv	167	32	silencing	silence	VBG
cord-256187-ofp7tupv	167	33	complex	complex	NN
cord-256187-ofp7tupv	167	34	.	.	.
cord-256187-ofp7tupv	168	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	168	2	,	,	,
cord-256187-ofp7tupv	168	3	it	-PRON-	PRP
cord-256187-ofp7tupv	168	4	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	168	5	the	the	DT
cord-256187-ofp7tupv	168	6	phosphorylation	phosphorylation	NN
cord-256187-ofp7tupv	168	7	of	of	IN
cord-256187-ofp7tupv	168	8	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	168	9	and	and	CC
cord-256187-ofp7tupv	168	10	therefore	therefore	RB
cord-256187-ofp7tupv	168	11	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	168	12	dimerization	dimerization	NN
cord-256187-ofp7tupv	168	13	,	,	,
cord-256187-ofp7tupv	168	14	translocation	translocation	NN
cord-256187-ofp7tupv	168	15	into	into	IN
cord-256187-ofp7tupv	168	16	the	the	DT
cord-256187-ofp7tupv	168	17	nucleus	nucleus	NN
cord-256187-ofp7tupv	168	18	and	and	CC
cord-256187-ofp7tupv	168	19	the	the	DT
cord-256187-ofp7tupv	168	20	expression	expression	NN
cord-256187-ofp7tupv	168	21	of	of	IN
cord-256187-ofp7tupv	168	22	IFN	IFN	NNP
cord-256187-ofp7tupv	168	23	-	-	HYPH
cord-256187-ofp7tupv	168	24	induced	induce	VBN
cord-256187-ofp7tupv	168	25	genes	gene	NNS
cord-256187-ofp7tupv	168	26	.	.	.
cord-256187-ofp7tupv	169	1	In	in	IN
cord-256187-ofp7tupv	169	2	addition	addition	NN
cord-256187-ofp7tupv	169	3	,	,	,
cord-256187-ofp7tupv	169	4	VP35	VP35	NNP
cord-256187-ofp7tupv	169	5	is	be	VBZ
cord-256187-ofp7tupv	169	6	able	able	JJ
cord-256187-ofp7tupv	169	7	to	to	TO
cord-256187-ofp7tupv	169	8	induce	induce	VB
cord-256187-ofp7tupv	169	9	SU	SU	NNP
cord-256187-ofp7tupv	169	10	-	-	HYPH
cord-256187-ofp7tupv	169	11	MOylation	MOylation	NNP
cord-256187-ofp7tupv	169	12	of	of	IN
cord-256187-ofp7tupv	169	13	IRF-7	IRF-7	NNP
cord-256187-ofp7tupv	169	14	and	and	CC
cord-256187-ofp7tupv	169	15	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	169	16	,	,	,
cord-256187-ofp7tupv	169	17	which	which	WDT
cord-256187-ofp7tupv	169	18	interferes	interfere	VBZ
cord-256187-ofp7tupv	169	19	with	with	IN
cord-256187-ofp7tupv	169	20	dimerization	dimerization	NN
cord-256187-ofp7tupv	169	21	and	and	CC
cord-256187-ofp7tupv	169	22	nuclear	nuclear	JJ
cord-256187-ofp7tupv	169	23	translocation	translocation	NN
cord-256187-ofp7tupv	169	24	.	.	.
cord-256187-ofp7tupv	170	1	IFN	IFN	NNP
cord-256187-ofp7tupv	170	2	,	,	,
cord-256187-ofp7tupv	170	3	interferon	interferon	NN
cord-256187-ofp7tupv	170	4	;	;	:
cord-256187-ofp7tupv	170	5	TLR	TLR	NNP
cord-256187-ofp7tupv	170	6	,	,	,
cord-256187-ofp7tupv	170	7	Toll	Toll	NNP
cord-256187-ofp7tupv	170	8	-	-	HYPH
cord-256187-ofp7tupv	170	9	like	like	JJ
cord-256187-ofp7tupv	170	10	receptor	receptor	NN
cord-256187-ofp7tupv	170	11	;	;	:
cord-256187-ofp7tupv	170	12	TRBP	TRBP	NNP
cord-256187-ofp7tupv	170	13	,	,	,
cord-256187-ofp7tupv	170	14	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	170	15	trans	trans	NNP
cord-256187-ofp7tupv	170	16	-	-	JJ
cord-256187-ofp7tupv	170	17	activation	activation	NNP
cord-256187-ofp7tupv	170	18	response	response	NN
cord-256187-ofp7tupv	170	19	RNA	rna	NN
cord-256187-ofp7tupv	170	20	-	-	HYPH
cord-256187-ofp7tupv	170	21	binding	bind	VBG
cord-256187-ofp7tupv	170	22	protein	protein	NN
cord-256187-ofp7tupv	170	23	;	;	:
cord-256187-ofp7tupv	170	24	PACT	pact	NN
cord-256187-ofp7tupv	170	25	,	,	,
cord-256187-ofp7tupv	170	26	protein	protein	NN
cord-256187-ofp7tupv	170	27	activator	activator	NN
cord-256187-ofp7tupv	170	28	of	of	IN
cord-256187-ofp7tupv	170	29	PKR	PKR	NNP
cord-256187-ofp7tupv	170	30	;	;	:
cord-256187-ofp7tupv	170	31	RIG	rig	NN
cord-256187-ofp7tupv	170	32	-	-	:
cord-256187-ofp7tupv	170	33	I	i	NN
cord-256187-ofp7tupv	170	34	,	,	,
cord-256187-ofp7tupv	170	35	retinoic	retinoic	JJ
cord-256187-ofp7tupv	170	36	acid	acid	NN
cord-256187-ofp7tupv	170	37	-	-	HYPH
cord-256187-ofp7tupv	170	38	inducible	inducible	JJ
cord-256187-ofp7tupv	170	39	gene	gene	NN
cord-256187-ofp7tupv	170	40	I	i	NN
cord-256187-ofp7tupv	170	41	;	;	:
cord-256187-ofp7tupv	170	42	MyD88	MyD88	NNS
cord-256187-ofp7tupv	170	43	,	,	,
cord-256187-ofp7tupv	170	44	myeloid	myeloid	JJ
cord-256187-ofp7tupv	170	45	differentiation	differentiation	NN
cord-256187-ofp7tupv	170	46	primary	primary	JJ
cord-256187-ofp7tupv	170	47	response	response	NN
cord-256187-ofp7tupv	170	48	protein	protein	NN
cord-256187-ofp7tupv	170	49	88	88	CD
cord-256187-ofp7tupv	170	50	;	;	:
cord-256187-ofp7tupv	170	51	TRIF	TRIF	NNP
cord-256187-ofp7tupv	170	52	,	,	,
cord-256187-ofp7tupv	170	53	TIR	TIR	NNP
cord-256187-ofp7tupv	170	54	domain	domain	NN
cord-256187-ofp7tupv	170	55	-	-	HYPH
cord-256187-ofp7tupv	170	56	containing	contain	VBG
cord-256187-ofp7tupv	170	57	adaptor	adaptor	NN
cord-256187-ofp7tupv	170	58	-	-	HYPH
cord-256187-ofp7tupv	170	59	inducing	induce	VBG
cord-256187-ofp7tupv	170	60	IFN	IFN	NNP
cord-256187-ofp7tupv	170	61	-	-	HYPH
cord-256187-ofp7tupv	170	62	b	b	NNP
cord-256187-ofp7tupv	170	63	;	;	:
cord-256187-ofp7tupv	170	64	IPS-1	IPS-1	NNP
cord-256187-ofp7tupv	171	1	,	,	,
cord-256187-ofp7tupv	171	2	IFN	IFN	NNP
cord-256187-ofp7tupv	171	3	-	-	HYPH
cord-256187-ofp7tupv	171	4	b	b	NNP
cord-256187-ofp7tupv	171	5	promoter	promoter	NN
cord-256187-ofp7tupv	171	6	stimulator	stimulator	NN
cord-256187-ofp7tupv	171	7	1	1	CD
cord-256187-ofp7tupv	171	8	;	;	:
cord-256187-ofp7tupv	171	9	TRAF6	TRAF6	NNP
cord-256187-ofp7tupv	171	10	,	,	,
cord-256187-ofp7tupv	171	11	tumour	tumour	NN
cord-256187-ofp7tupv	171	12	necrosis	necrosis	NN
cord-256187-ofp7tupv	171	13	factor	factor	NN
cord-256187-ofp7tupv	171	14	receptor	receptor	NN
cord-256187-ofp7tupv	171	15	-	-	HYPH
cord-256187-ofp7tupv	171	16	associated	associate	VBN
cord-256187-ofp7tupv	171	17	factor	factor	NN
cord-256187-ofp7tupv	171	18	6	6	CD
cord-256187-ofp7tupv	171	19	;	;	:
cord-256187-ofp7tupv	171	20	IRAK	IRAK	NNP
cord-256187-ofp7tupv	171	21	,	,	,
cord-256187-ofp7tupv	171	22	interleukin-1	interleukin-1	NNP
cord-256187-ofp7tupv	171	23	receptor	receptor	NN
cord-256187-ofp7tupv	171	24	-	-	HYPH
cord-256187-ofp7tupv	171	25	associated	associate	VBN
cord-256187-ofp7tupv	171	26	kinase	kinase	NN
cord-256187-ofp7tupv	171	27	;	;	:
cord-256187-ofp7tupv	171	28	IKKe	IKKe	NNS
cord-256187-ofp7tupv	171	29	,	,	,
cord-256187-ofp7tupv	171	30	IjB	ijb	NN
cord-256187-ofp7tupv	171	31	kinase	kinase	NN
cord-256187-ofp7tupv	171	32	e	e	NNP
cord-256187-ofp7tupv	171	33	;	;	:
cord-256187-ofp7tupv	171	34	TBK1	TBK1	NNP
cord-256187-ofp7tupv	171	35	,	,	,
cord-256187-ofp7tupv	171	36	tank	tank	NN
cord-256187-ofp7tupv	171	37	-	-	HYPH
cord-256187-ofp7tupv	171	38	binding	binding	NN
cord-256187-ofp7tupv	171	39	kinase	kinase	NN
cord-256187-ofp7tupv	171	40	1	1	CD
cord-256187-ofp7tupv	171	41	;	;	:
cord-256187-ofp7tupv	171	42	IRF	IRF	NNP
cord-256187-ofp7tupv	171	43	,	,	,
cord-256187-ofp7tupv	171	44	IFN	IFN	NNP
cord-256187-ofp7tupv	171	45	regulatory	regulatory	JJ
cord-256187-ofp7tupv	171	46	factor	factor	NN
cord-256187-ofp7tupv	171	47	;	;	:
cord-256187-ofp7tupv	171	48	ISG	ISG	NNP
cord-256187-ofp7tupv	171	49	,	,	,
cord-256187-ofp7tupv	171	50	IFN	IFN	NNP
cord-256187-ofp7tupv	171	51	-	-	HYPH
cord-256187-ofp7tupv	171	52	stimulated	stimulate	VBN
cord-256187-ofp7tupv	171	53	gene	gene	NN
cord-256187-ofp7tupv	171	54	;	;	:
cord-256187-ofp7tupv	171	55	PKR	PKR	NNP
cord-256187-ofp7tupv	171	56	,	,	,
cord-256187-ofp7tupv	171	57	dsRNA	dsrna	JJ
cord-256187-ofp7tupv	171	58	-	-	HYPH
cord-256187-ofp7tupv	171	59	dependent	dependent	JJ
cord-256187-ofp7tupv	171	60	protein	protein	NN
cord-256187-ofp7tupv	171	61	kinase	kinase	NN
cord-256187-ofp7tupv	171	62	;	;	:
cord-256187-ofp7tupv	171	63	IFITM	IFITM	NNP
cord-256187-ofp7tupv	171	64	,	,	,
cord-256187-ofp7tupv	171	65	IFN	IFN	NNP
cord-256187-ofp7tupv	171	66	-	-	HYPH
cord-256187-ofp7tupv	171	67	induced	induce	VBN
cord-256187-ofp7tupv	171	68	transmembrane	transmembrane	NN
cord-256187-ofp7tupv	171	69	protein	protein	NN
cord-256187-ofp7tupv	171	70	.	.	.
cord-256187-ofp7tupv	172	1	the	the	DT
cord-256187-ofp7tupv	172	2	disruption	disruption	NN
cord-256187-ofp7tupv	172	3	of	of	IN
cord-256187-ofp7tupv	172	4	the	the	DT
cord-256187-ofp7tupv	172	5	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	172	6	inhibitory	inhibitory	JJ
cord-256187-ofp7tupv	172	7	activity	activity	NN
cord-256187-ofp7tupv	172	8	of	of	IN
cord-256187-ofp7tupv	172	9	VP35	VP35	NNP
cord-256187-ofp7tupv	172	10	does	do	VBZ
cord-256187-ofp7tupv	172	11	not	not	RB
cord-256187-ofp7tupv	172	12	influence	influence	VB
cord-256187-ofp7tupv	172	13	the	the	DT
cord-256187-ofp7tupv	172	14	function	function	NN
cord-256187-ofp7tupv	172	15	of	of	IN
cord-256187-ofp7tupv	172	16	VP35	VP35	NNP
cord-256187-ofp7tupv	172	17	in	in	IN
cord-256187-ofp7tupv	172	18	viral	viral	JJ
cord-256187-ofp7tupv	172	19	replication	replication	NN
cord-256187-ofp7tupv	172	20	and	and	CC
cord-256187-ofp7tupv	172	21	transcription	transcription	NN
cord-256187-ofp7tupv	172	22	,	,	,
cord-256187-ofp7tupv	172	23	as	as	IN
cord-256187-ofp7tupv	172	24	amino	amino	NN
cord-256187-ofp7tupv	172	25	acid	acid	NN
cord-256187-ofp7tupv	172	26	residues	residue	NNS
cord-256187-ofp7tupv	172	27	essential	essential	JJ
cord-256187-ofp7tupv	172	28	for	for	IN
cord-256187-ofp7tupv	172	29	polymerase	polymerase	NN
cord-256187-ofp7tupv	172	30	cofactor	cofactor	NN
cord-256187-ofp7tupv	172	31	function	function	NN
cord-256187-ofp7tupv	172	32	of	of	IN
cord-256187-ofp7tupv	172	33	VP35	VP35	NNP
cord-256187-ofp7tupv	172	34	differ	differ	VBP
cord-256187-ofp7tupv	172	35	from	from	IN
cord-256187-ofp7tupv	172	36	those	those	DT
cord-256187-ofp7tupv	172	37	required	require	VBN
cord-256187-ofp7tupv	172	38	for	for	IN
cord-256187-ofp7tupv	172	39	IFN	IFN	NNP
cord-256187-ofp7tupv	172	40	antagonism	antagonism	NN
cord-256187-ofp7tupv	172	41	(	(	-LRB-
cord-256187-ofp7tupv	172	42	Prins	Prins	NNP
cord-256187-ofp7tupv	172	43	et	et	NNP
cord-256187-ofp7tupv	172	44	al	al	NNP
cord-256187-ofp7tupv	172	45	.	.	NNP
cord-256187-ofp7tupv	172	46	,	,	,
cord-256187-ofp7tupv	172	47	2010a	2010a	CD
cord-256187-ofp7tupv	172	48	)	)	-RRB-
cord-256187-ofp7tupv	172	49	.	.	.
cord-256187-ofp7tupv	173	1	Sequences	sequence	NNS
cord-256187-ofp7tupv	173	2	in	in	IN
cord-256187-ofp7tupv	173	3	the	the	DT
cord-256187-ofp7tupv	173	4	C	c	NN
cord-256187-ofp7tupv	173	5	-	-	HYPH
cord-256187-ofp7tupv	173	6	terminus	terminus	NN
cord-256187-ofp7tupv	173	7	of	of	IN
cord-256187-ofp7tupv	173	8	VP35	VP35	NNP
cord-256187-ofp7tupv	173	9	resemble	resemble	VBP
cord-256187-ofp7tupv	173	10	the	the	DT
cord-256187-ofp7tupv	173	11	dsRNA	dsrna	NN
cord-256187-ofp7tupv	173	12	-	-	HYPH
cord-256187-ofp7tupv	173	13	binding	bind	VBG
cord-256187-ofp7tupv	173	14	domain	domain	NN
cord-256187-ofp7tupv	173	15	of	of	IN
cord-256187-ofp7tupv	173	16	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	173	17	NS1	NS1	NNP
cord-256187-ofp7tupv	173	18	,	,	,
cord-256187-ofp7tupv	173	19	which	which	WDT
cord-256187-ofp7tupv	173	20	is	be	VBZ
cord-256187-ofp7tupv	173	21	important	important	JJ
cord-256187-ofp7tupv	173	22	for	for	IN
cord-256187-ofp7tupv	173	23	IFN	IFN	NNP
cord-256187-ofp7tupv	173	24	antagonism	antagonism	NN
cord-256187-ofp7tupv	173	25	(	(	-LRB-
cord-256187-ofp7tupv	173	26	Donelan	Donelan	NNP
cord-256187-ofp7tupv	173	27	et	et	FW
cord-256187-ofp7tupv	173	28	al	al	NNP
cord-256187-ofp7tupv	173	29	.	.	NNP
cord-256187-ofp7tupv	173	30	,	,	,
cord-256187-ofp7tupv	173	31	2003	2003	CD
cord-256187-ofp7tupv	173	32	;	;	:
cord-256187-ofp7tupv	173	33	Hartman	Hartman	NNP
cord-256187-ofp7tupv	173	34	et	et	NNP
cord-256187-ofp7tupv	173	35	al	al	NNP
cord-256187-ofp7tupv	173	36	.	.	NNP
cord-256187-ofp7tupv	173	37	,	,	,
cord-256187-ofp7tupv	173	38	2004	2004	CD
cord-256187-ofp7tupv	173	39	)	)	-RRB-
cord-256187-ofp7tupv	173	40	.	.	.
cord-256187-ofp7tupv	174	1	Indeed	indeed	RB
cord-256187-ofp7tupv	174	2	,	,	,
cord-256187-ofp7tupv	174	3	VP35	VP35	NNP
cord-256187-ofp7tupv	174	4	is	be	VBZ
cord-256187-ofp7tupv	174	5	able	able	JJ
cord-256187-ofp7tupv	174	6	to	to	TO
cord-256187-ofp7tupv	174	7	bind	bind	VB
cord-256187-ofp7tupv	174	8	dsRNA	dsrna	NN
cord-256187-ofp7tupv	174	9	,	,	,
cord-256187-ofp7tupv	174	10	but	but	CC
cord-256187-ofp7tupv	174	11	not	not	RB
cord-256187-ofp7tupv	174	12	single	single	RB
cord-256187-ofp7tupv	174	13	-	-	HYPH
cord-256187-ofp7tupv	174	14	stranded	stranded	JJ
cord-256187-ofp7tupv	174	15	(	(	-LRB-
cord-256187-ofp7tupv	174	16	ss	ss	NNP
cord-256187-ofp7tupv	174	17	)	)	-RRB-
cord-256187-ofp7tupv	174	18	RNA	RNA	NNP
cord-256187-ofp7tupv	174	19	or	or	CC
cord-256187-ofp7tupv	174	20	dsDNA	dsdna	RB
cord-256187-ofp7tupv	174	21	and	and	CC
cord-256187-ofp7tupv	174	22	mutations	mutation	NNS
cord-256187-ofp7tupv	174	23	in	in	IN
cord-256187-ofp7tupv	174	24	the	the	DT
cord-256187-ofp7tupv	174	25	central	central	JJ
cord-256187-ofp7tupv	174	26	basic	basic	JJ
cord-256187-ofp7tupv	174	27	patch	patch	NN
cord-256187-ofp7tupv	174	28	of	of	IN
cord-256187-ofp7tupv	174	29	IID	IID	NNP
cord-256187-ofp7tupv	174	30	,	,	,
cord-256187-ofp7tupv	174	31	which	which	WDT
cord-256187-ofp7tupv	174	32	abrogate	abrogate	VBP
cord-256187-ofp7tupv	174	33	IFN	IFN	NNP
cord-256187-ofp7tupv	174	34	antagonism	antagonism	NN
cord-256187-ofp7tupv	174	35	were	be	VBD
cord-256187-ofp7tupv	174	36	found	find	VBN
cord-256187-ofp7tupv	174	37	to	to	TO
cord-256187-ofp7tupv	174	38	be	be	VB
cord-256187-ofp7tupv	174	39	incompatible	incompatible	JJ
cord-256187-ofp7tupv	174	40	with	with	IN
cord-256187-ofp7tupv	174	41	dsRNA	dsRNA	``
cord-256187-ofp7tupv	174	42	binding	bind	VBG
cord-256187-ofp7tupv	174	43	(	(	-LRB-
cord-256187-ofp7tupv	174	44	Cárdenas	Cárdenas	NNP
cord-256187-ofp7tupv	174	45	et	et	NNP
cord-256187-ofp7tupv	174	46	al	al	NNP
cord-256187-ofp7tupv	174	47	.	.	NNP
cord-256187-ofp7tupv	174	48	,	,	,
cord-256187-ofp7tupv	174	49	2006	2006	CD
cord-256187-ofp7tupv	174	50	;	;	:
cord-256187-ofp7tupv	174	51	Leung	Leung	NNP
cord-256187-ofp7tupv	174	52	et	et	NNP
cord-256187-ofp7tupv	174	53	al	al	NNP
cord-256187-ofp7tupv	174	54	.	.	NNP
cord-256187-ofp7tupv	174	55	,	,	,
cord-256187-ofp7tupv	174	56	2010	2010	CD
cord-256187-ofp7tupv	174	57	;	;	:
cord-256187-ofp7tupv	174	58	Prins	Prins	NNP
cord-256187-ofp7tupv	174	59	et	et	NNP
cord-256187-ofp7tupv	174	60	al	al	NNP
cord-256187-ofp7tupv	174	61	.	.	NNP
cord-256187-ofp7tupv	174	62	,	,	,
cord-256187-ofp7tupv	174	63	2010b	2010b	CD
cord-256187-ofp7tupv	174	64	)	)	-RRB-
cord-256187-ofp7tupv	174	65	.	.	.
cord-256187-ofp7tupv	175	1	The	the	DT
cord-256187-ofp7tupv	175	2	structure	structure	NN
cord-256187-ofp7tupv	175	3	of	of	IN
cord-256187-ofp7tupv	175	4	VP35	VP35	NNP
cord-256187-ofp7tupv	175	5	IID	IID	NNP
cord-256187-ofp7tupv	175	6	in	in	IN
cord-256187-ofp7tupv	175	7	complex	complex	NN
cord-256187-ofp7tupv	175	8	with	with	IN
cord-256187-ofp7tupv	175	9	dsRNA	dsrna	NN
cord-256187-ofp7tupv	175	10	has	have	VBZ
cord-256187-ofp7tupv	175	11	been	be	VBN
cord-256187-ofp7tupv	175	12	determined	determine	VBN
cord-256187-ofp7tupv	175	13	at	at	IN
cord-256187-ofp7tupv	175	14	the	the	DT
cord-256187-ofp7tupv	175	15	atomic	atomic	JJ
cord-256187-ofp7tupv	175	16	level	level	NN
cord-256187-ofp7tupv	175	17	(	(	-LRB-
cord-256187-ofp7tupv	175	18	Kimberlin	Kimberlin	NNP
cord-256187-ofp7tupv	175	19	et	et	FW
cord-256187-ofp7tupv	175	20	al	al	NNP
cord-256187-ofp7tupv	175	21	.	.	NNP
cord-256187-ofp7tupv	175	22	,	,	,
cord-256187-ofp7tupv	175	23	2010	2010	CD
cord-256187-ofp7tupv	175	24	;	;	:
cord-256187-ofp7tupv	175	25	Leung	Leung	NNP
cord-256187-ofp7tupv	175	26	et	et	NNP
cord-256187-ofp7tupv	175	27	al	al	NNP
cord-256187-ofp7tupv	175	28	.	.	NNP
cord-256187-ofp7tupv	175	29	,	,	,
cord-256187-ofp7tupv	175	30	2010	2010	CD
cord-256187-ofp7tupv	175	31	)	)	-RRB-
cord-256187-ofp7tupv	175	32	,	,	,
cord-256187-ofp7tupv	175	33	and	and	CC
cord-256187-ofp7tupv	175	34	the	the	DT
cord-256187-ofp7tupv	175	35	protein	protein	NN
cord-256187-ofp7tupv	175	36	was	be	VBD
cord-256187-ofp7tupv	175	37	found	find	VBN
cord-256187-ofp7tupv	175	38	to	to	TO
cord-256187-ofp7tupv	175	39	display	display	VB
cord-256187-ofp7tupv	175	40	a	a	DT
cord-256187-ofp7tupv	175	41	unique	unique	JJ
cord-256187-ofp7tupv	175	42	fold	fold	NN
cord-256187-ofp7tupv	175	43	compared	compare	VBN
cord-256187-ofp7tupv	175	44	with	with	IN
cord-256187-ofp7tupv	175	45	known	know	VBN
cord-256187-ofp7tupv	175	46	dsRNA	dsrna	RB
cord-256187-ofp7tupv	175	47	-	-	HYPH
cord-256187-ofp7tupv	175	48	binding	bind	VBG
cord-256187-ofp7tupv	175	49	proteins	protein	NNS
cord-256187-ofp7tupv	175	50	,	,	,
cord-256187-ofp7tupv	175	51	including	include	VBG
cord-256187-ofp7tupv	175	52	that	that	DT
cord-256187-ofp7tupv	175	53	of	of	IN
cord-256187-ofp7tupv	175	54	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	175	55	NS1	NS1	NNP
cord-256187-ofp7tupv	175	56	(	(	-LRB-
cord-256187-ofp7tupv	175	57	Leung	Leung	NNP
cord-256187-ofp7tupv	175	58	et	et	NNP
cord-256187-ofp7tupv	175	59	al	al	NNP
cord-256187-ofp7tupv	175	60	.	.	NNP
cord-256187-ofp7tupv	175	61	,	,	,
cord-256187-ofp7tupv	175	62	2009	2009	CD
cord-256187-ofp7tupv	175	63	)	)	-RRB-
cord-256187-ofp7tupv	175	64	.	.	.
cord-256187-ofp7tupv	176	1	Interestingly	interestingly	RB
cord-256187-ofp7tupv	176	2	,	,	,
cord-256187-ofp7tupv	176	3	VP35	VP35	NNP
cord-256187-ofp7tupv	176	4	displays	display	VBZ
cord-256187-ofp7tupv	176	5	a	a	DT
cord-256187-ofp7tupv	176	6	bimodal	bimodal	JJ
cord-256187-ofp7tupv	176	7	dsRNA	dsrna	RB
cord-256187-ofp7tupv	176	8	-	-	HYPH
cord-256187-ofp7tupv	176	9	binding	bind	VBG
cord-256187-ofp7tupv	176	10	strategy	strategy	NN
cord-256187-ofp7tupv	176	11	.	.	.
cord-256187-ofp7tupv	177	1	Upon	upon	IN
cord-256187-ofp7tupv	177	2	dsRNA	dsrna	NN
cord-256187-ofp7tupv	177	3	recognition	recognition	NN
cord-256187-ofp7tupv	177	4	,	,	,
cord-256187-ofp7tupv	177	5	VP35	VP35	NNP
cord-256187-ofp7tupv	177	6	builds	build	VBZ
cord-256187-ofp7tupv	177	7	asymmetric	asymmetric	JJ
cord-256187-ofp7tupv	177	8	dimers	dimer	NNS
cord-256187-ofp7tupv	177	9	;	;	:
cord-256187-ofp7tupv	177	10	one	one	CD
cord-256187-ofp7tupv	177	11	monomer	monomer	NN
cord-256187-ofp7tupv	177	12	binds	bind	VBZ
cord-256187-ofp7tupv	177	13	the	the	DT
cord-256187-ofp7tupv	177	14	dsRNA	dsrna	NN
cord-256187-ofp7tupv	177	15	phosphate	phosphate	NN
cord-256187-ofp7tupv	177	16	backbone	backbone	NN
cord-256187-ofp7tupv	177	17	,	,	,
cord-256187-ofp7tupv	177	18	whereas	whereas	IN
cord-256187-ofp7tupv	177	19	the	the	DT
cord-256187-ofp7tupv	177	20	other	other	JJ
cord-256187-ofp7tupv	177	21	binds	bind	VBZ
cord-256187-ofp7tupv	177	22	terminal	terminal	JJ
cord-256187-ofp7tupv	177	23	nucleotides	nucleotide	NNS
cord-256187-ofp7tupv	177	24	of	of	IN
cord-256187-ofp7tupv	177	25	the	the	DT
cord-256187-ofp7tupv	177	26	dsRNA	dsrna	NN
cord-256187-ofp7tupv	177	27	molecule	molecule	NN
cord-256187-ofp7tupv	177	28	(	(	-LRB-
cord-256187-ofp7tupv	177	29	Kimberlin	Kimberlin	NNP
cord-256187-ofp7tupv	177	30	et	et	FW
cord-256187-ofp7tupv	177	31	al	al	NNP
cord-256187-ofp7tupv	177	32	.	.	NNP
cord-256187-ofp7tupv	177	33	,	,	,
cord-256187-ofp7tupv	177	34	2010	2010	CD
cord-256187-ofp7tupv	177	35	;	;	:
cord-256187-ofp7tupv	177	36	Leung	Leung	NNP
cord-256187-ofp7tupv	177	37	et	et	NNP
cord-256187-ofp7tupv	177	38	al	al	NNP
cord-256187-ofp7tupv	177	39	.	.	NNP
cord-256187-ofp7tupv	177	40	,	,	,
cord-256187-ofp7tupv	177	41	2010	2010	CD
cord-256187-ofp7tupv	177	42	)	)	-RRB-
cord-256187-ofp7tupv	177	43	.	.	.
cord-256187-ofp7tupv	178	1	This	this	DT
cord-256187-ofp7tupv	178	2	dsRNA	dsrna	RB
cord-256187-ofp7tupv	178	3	-	-	HYPH
cord-256187-ofp7tupv	178	4	binding	bind	VBG
cord-256187-ofp7tupv	178	5	mode	mode	NN
cord-256187-ofp7tupv	178	6	of	of	IN
cord-256187-ofp7tupv	178	7	VP35	VP35	NNP
cord-256187-ofp7tupv	178	8	dimers	dimer	NNS
cord-256187-ofp7tupv	178	9	seems	seem	VBZ
cord-256187-ofp7tupv	178	10	to	to	TO
cord-256187-ofp7tupv	178	11	mimic	mimic	VB
cord-256187-ofp7tupv	178	12	that	that	DT
cord-256187-ofp7tupv	178	13	of	of	IN
cord-256187-ofp7tupv	178	14	RIG	rig	NN
cord-256187-ofp7tupv	178	15	-	-	:
cord-256187-ofp7tupv	178	16	I	I	NNP
cord-256187-ofp7tupv	178	17	,	,	,
cord-256187-ofp7tupv	178	18	a	a	DT
cord-256187-ofp7tupv	178	19	key	key	JJ
cord-256187-ofp7tupv	178	20	cellular	cellular	JJ
cord-256187-ofp7tupv	178	21	sensor	sensor	NN
cord-256187-ofp7tupv	178	22	of	of	IN
cord-256187-ofp7tupv	178	23	dsRNA	dsrna	NN
cord-256187-ofp7tupv	178	24	,	,	,
cord-256187-ofp7tupv	178	25	and	and	CC
cord-256187-ofp7tupv	178	26	VP35	VP35	NNP
cord-256187-ofp7tupv	178	27	and	and	CC
cord-256187-ofp7tupv	178	28	RIG	rig	NN
cord-256187-ofp7tupv	178	29	-	-	:
cord-256187-ofp7tupv	178	30	I	-PRON-	PRP
cord-256187-ofp7tupv	178	31	might	may	MD
cord-256187-ofp7tupv	178	32	occupy	occupy	VB
cord-256187-ofp7tupv	178	33	overlapping	overlap	VBG
cord-256187-ofp7tupv	178	34	binding	bind	VBG
cord-256187-ofp7tupv	178	35	sites	site	NNS
cord-256187-ofp7tupv	178	36	on	on	IN
cord-256187-ofp7tupv	178	37	dsRNA	dsrna	NN
cord-256187-ofp7tupv	179	1	(	(	-LRB-
cord-256187-ofp7tupv	179	2	Kimberlin	Kimberlin	NNP
cord-256187-ofp7tupv	179	3	et	et	FW
cord-256187-ofp7tupv	179	4	al	al	NNP
cord-256187-ofp7tupv	179	5	.	.	NNP
cord-256187-ofp7tupv	179	6	,	,	,
cord-256187-ofp7tupv	179	7	2010	2010	CD
cord-256187-ofp7tupv	179	8	;	;	:
cord-256187-ofp7tupv	179	9	Leung	Leung	NNP
cord-256187-ofp7tupv	179	10	et	et	NNP
cord-256187-ofp7tupv	179	11	al	al	NNP
cord-256187-ofp7tupv	179	12	.	.	NNP
cord-256187-ofp7tupv	179	13	,	,	,
cord-256187-ofp7tupv	179	14	2010	2010	CD
cord-256187-ofp7tupv	179	15	)	)	-RRB-
cord-256187-ofp7tupv	179	16	.	.	.
cord-256187-ofp7tupv	180	1	These	these	DT
cord-256187-ofp7tupv	180	2	findings	finding	NNS
cord-256187-ofp7tupv	180	3	suggest	suggest	VBP
cord-256187-ofp7tupv	180	4	that	that	IN
cord-256187-ofp7tupv	180	5	VP35	VP35	NNP
cord-256187-ofp7tupv	180	6	may	may	MD
cord-256187-ofp7tupv	180	7	sequester	sequester	VB
cord-256187-ofp7tupv	180	8	dsRNA	dsrna	NN
cord-256187-ofp7tupv	180	9	from	from	IN
cord-256187-ofp7tupv	180	10	recognition	recognition	NN
cord-256187-ofp7tupv	180	11	by	by	IN
cord-256187-ofp7tupv	180	12	RIG	rig	NN
cord-256187-ofp7tupv	180	13	-	-	:
cord-256187-ofp7tupv	180	14	I	-PRON-	PRP
cord-256187-ofp7tupv	180	15	and	and	CC
cord-256187-ofp7tupv	180	16	potentially	potentially	RB
cord-256187-ofp7tupv	180	17	other	other	JJ
cord-256187-ofp7tupv	180	18	dsRNA	dsrna	RB
cord-256187-ofp7tupv	180	19	-	-	HYPH
cord-256187-ofp7tupv	180	20	binding	bind	VBG
cord-256187-ofp7tupv	180	21	molecules	molecule	NNS
cord-256187-ofp7tupv	180	22	such	such	JJ
cord-256187-ofp7tupv	180	23	as	as	IN
cord-256187-ofp7tupv	180	24	MDA-5	MDA-5	NNP
cord-256187-ofp7tupv	180	25	or	or	CC
cord-256187-ofp7tupv	180	26	Dicer	Dicer	NNP
cord-256187-ofp7tupv	180	27	(	(	-LRB-
cord-256187-ofp7tupv	180	28	Kimberlin	Kimberlin	NNP
cord-256187-ofp7tupv	180	29	et	et	FW
cord-256187-ofp7tupv	180	30	al	al	NNP
cord-256187-ofp7tupv	180	31	.	.	NNP
cord-256187-ofp7tupv	180	32	,	,	,
cord-256187-ofp7tupv	180	33	2010	2010	CD
cord-256187-ofp7tupv	180	34	;	;	:
cord-256187-ofp7tupv	180	35	.	.	.
cord-256187-ofp7tupv	181	1	In	in	IN
cord-256187-ofp7tupv	181	2	addition	addition	NN
cord-256187-ofp7tupv	181	3	,	,	,
cord-256187-ofp7tupv	181	4	differences	difference	NNS
cord-256187-ofp7tupv	181	5	in	in	IN
cord-256187-ofp7tupv	181	6	the	the	DT
cord-256187-ofp7tupv	181	7	structural	structural	JJ
cord-256187-ofp7tupv	181	8	organization	organization	NN
cord-256187-ofp7tupv	181	9	and	and	CC
cord-256187-ofp7tupv	181	10	dsRNA	dsrna	NN
cord-256187-ofp7tupv	181	11	binding	binding	NN
cord-256187-ofp7tupv	181	12	of	of	IN
cord-256187-ofp7tupv	181	13	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	181	14	and	and	CC
cord-256187-ofp7tupv	181	15	REBOV	REBOV	NNP
cord-256187-ofp7tupv	181	16	VP35	VP35	NNP
cord-256187-ofp7tupv	181	17	were	be	VBD
cord-256187-ofp7tupv	181	18	identified	identify	VBN
cord-256187-ofp7tupv	181	19	,	,	,
cord-256187-ofp7tupv	181	20	which	which	WDT
cord-256187-ofp7tupv	181	21	might	may	MD
cord-256187-ofp7tupv	181	22	contribute	contribute	VB
cord-256187-ofp7tupv	181	23	to	to	IN
cord-256187-ofp7tupv	181	24	the	the	DT
cord-256187-ofp7tupv	181	25	differential	differential	JJ
cord-256187-ofp7tupv	181	26	pathogenicity	pathogenicity	NN
cord-256187-ofp7tupv	181	27	of	of	IN
cord-256187-ofp7tupv	181	28	these	these	DT
cord-256187-ofp7tupv	181	29	viruses	virus	NNS
cord-256187-ofp7tupv	181	30	in	in	IN
cord-256187-ofp7tupv	181	31	humans	human	NNS
cord-256187-ofp7tupv	182	1	(	(	-LRB-
cord-256187-ofp7tupv	182	2	Kimberlin	Kimberlin	NNP
cord-256187-ofp7tupv	182	3	et	et	FW
cord-256187-ofp7tupv	182	4	al	al	NNP
cord-256187-ofp7tupv	182	5	.	.	NNP
cord-256187-ofp7tupv	182	6	,	,	,
cord-256187-ofp7tupv	182	7	2010	2010	CD
cord-256187-ofp7tupv	182	8	;	;	:
cord-256187-ofp7tupv	182	9	Leung	Leung	NNP
cord-256187-ofp7tupv	182	10	et	et	NNP
cord-256187-ofp7tupv	182	11	al	al	NNP
cord-256187-ofp7tupv	182	12	.	.	NNP
cord-256187-ofp7tupv	182	13	,	,	,
cord-256187-ofp7tupv	182	14	2010	2010	CD
cord-256187-ofp7tupv	182	15	)	)	-RRB-
cord-256187-ofp7tupv	182	16	,	,	,
cord-256187-ofp7tupv	182	17	although	although	IN
cord-256187-ofp7tupv	182	18	it	-PRON-	PRP
cord-256187-ofp7tupv	182	19	needs	need	VBZ
cord-256187-ofp7tupv	182	20	to	to	TO
cord-256187-ofp7tupv	182	21	be	be	VB
cord-256187-ofp7tupv	182	22	noted	note	VBN
cord-256187-ofp7tupv	182	23	that	that	IN
cord-256187-ofp7tupv	182	24	both	both	DT
cord-256187-ofp7tupv	182	25	viruses	virus	NNS
cord-256187-ofp7tupv	182	26	are	be	VBP
cord-256187-ofp7tupv	182	27	highly	highly	RB
cord-256187-ofp7tupv	182	28	pathogenic	pathogenic	JJ
cord-256187-ofp7tupv	182	29	in	in	IN
cord-256187-ofp7tupv	182	30	macaques	macaque	NNS
cord-256187-ofp7tupv	182	31	.	.	.
cord-256187-ofp7tupv	183	1	VP35	VP35	NNP
cord-256187-ofp7tupv	183	2	promotes	promote	VBZ
cord-256187-ofp7tupv	183	3	SUMOylation	sumoylation	NN
cord-256187-ofp7tupv	183	4	of	of	IN
cord-256187-ofp7tupv	183	5	IFR-7	IFR-7	NNP
cord-256187-ofp7tupv	183	6	via	via	IN
cord-256187-ofp7tupv	183	7	PIAS1	PIAS1	NNS
cord-256187-ofp7tupv	183	8	IFR-7	ifr-7	RB
cord-256187-ofp7tupv	184	1	but	but	CC
cord-256187-ofp7tupv	184	2	not	not	RB
cord-256187-ofp7tupv	184	3	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	184	4	is	be	VBZ
cord-256187-ofp7tupv	184	5	critical	critical	JJ
cord-256187-ofp7tupv	184	6	for	for	IN
cord-256187-ofp7tupv	184	7	the	the	DT
cord-256187-ofp7tupv	184	8	production	production	NN
cord-256187-ofp7tupv	184	9	of	of	IN
cord-256187-ofp7tupv	184	10	type	type	NN
cord-256187-ofp7tupv	184	11	I	-PRON-	PRP
cord-256187-ofp7tupv	184	12	IFNs	ifns	VBP
cord-256187-ofp7tupv	184	13	(	(	-LRB-
cord-256187-ofp7tupv	184	14	Honda	Honda	NNP
cord-256187-ofp7tupv	184	15	et	et	NNP
cord-256187-ofp7tupv	184	16	al	al	NNP
cord-256187-ofp7tupv	184	17	.	.	NNP
cord-256187-ofp7tupv	184	18	,	,	,
cord-256187-ofp7tupv	184	19	2005	2005	CD
cord-256187-ofp7tupv	184	20	)	)	-RRB-
cord-256187-ofp7tupv	184	21	,	,	,
cord-256187-ofp7tupv	184	22	and	and	CC
cord-256187-ofp7tupv	184	23	a	a	DT
cord-256187-ofp7tupv	184	24	recent	recent	JJ
cord-256187-ofp7tupv	184	25	study	study	NN
cord-256187-ofp7tupv	184	26	shows	show	VBZ
cord-256187-ofp7tupv	184	27	that	that	IN
cord-256187-ofp7tupv	184	28	VP35	VP35	NNP
cord-256187-ofp7tupv	184	29	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	184	30	IRF-7	irf-7	XX
cord-256187-ofp7tupv	184	31	by	by	IN
cord-256187-ofp7tupv	184	32	promoting	promote	VBG
cord-256187-ofp7tupv	184	33	its	-PRON-	PRP$
cord-256187-ofp7tupv	184	34	SUMOylation	sumoylation	NN
cord-256187-ofp7tupv	184	35	(	(	-LRB-
cord-256187-ofp7tupv	184	36	Chang	Chang	NNP
cord-256187-ofp7tupv	184	37	et	et	NNP
cord-256187-ofp7tupv	184	38	al	al	NNP
cord-256187-ofp7tupv	184	39	.	.	NNP
cord-256187-ofp7tupv	184	40	,	,	,
cord-256187-ofp7tupv	184	41	2009	2009	CD
cord-256187-ofp7tupv	184	42	)	)	-RRB-
cord-256187-ofp7tupv	184	43	.	.	.
cord-256187-ofp7tupv	185	1	Thus	thus	RB
cord-256187-ofp7tupv	185	2	,	,	,
cord-256187-ofp7tupv	185	3	VP35	VP35	NNP
cord-256187-ofp7tupv	185	4	forms	form	VBZ
cord-256187-ofp7tupv	185	5	a	a	DT
cord-256187-ofp7tupv	185	6	complex	complex	NN
cord-256187-ofp7tupv	185	7	with	with	IN
cord-256187-ofp7tupv	186	1	IRF-7	IRF-7	NNP
cord-256187-ofp7tupv	186	2	and	and	CC
cord-256187-ofp7tupv	186	3	PIAS1	PIAS1	NNP
cord-256187-ofp7tupv	187	1	(	(	-LRB-
cord-256187-ofp7tupv	187	2	the	the	DT
cord-256187-ofp7tupv	187	3	small	small	JJ
cord-256187-ofp7tupv	187	4	ubiquitin	ubiquitin	NN
cord-256187-ofp7tupv	187	5	-	-	HYPH
cord-256187-ofp7tupv	187	6	like	like	JJ
cord-256187-ofp7tupv	187	7	modifier	modifier	NN
cord-256187-ofp7tupv	187	8	(	(	-LRB-
cord-256187-ofp7tupv	187	9	SUMO	SUMO	NNP
cord-256187-ofp7tupv	187	10	)	)	-RRB-
cord-256187-ofp7tupv	187	11	E3	e3	NN
cord-256187-ofp7tupv	187	12	ligase	ligase	NN
cord-256187-ofp7tupv	187	13	protein	protein	NN
cord-256187-ofp7tupv	187	14	inhibitor	inhibitor	NN
cord-256187-ofp7tupv	187	15	of	of	IN
cord-256187-ofp7tupv	187	16	activated	activate	VBN
cord-256187-ofp7tupv	187	17	STAT	stat	NN
cord-256187-ofp7tupv	187	18	)	)	-RRB-
cord-256187-ofp7tupv	187	19	and	and	CC
cord-256187-ofp7tupv	187	20	promotes	promote	VBZ
cord-256187-ofp7tupv	187	21	IRF-7	IRF-7	NNP
cord-256187-ofp7tupv	187	22	SUMOylation	sumoylation	NN
cord-256187-ofp7tupv	187	23	via	via	IN
cord-256187-ofp7tupv	187	24	PIAS1	PIAS1	NNS
cord-256187-ofp7tupv	188	1	(	(	-LRB-
cord-256187-ofp7tupv	188	2	Chang	Chang	NNP
cord-256187-ofp7tupv	188	3	et	et	NNP
cord-256187-ofp7tupv	188	4	al	al	NNP
cord-256187-ofp7tupv	188	5	.	.	NNP
cord-256187-ofp7tupv	188	6	,	,	,
cord-256187-ofp7tupv	188	7	2009	2009	CD
cord-256187-ofp7tupv	188	8	)	)	-RRB-
cord-256187-ofp7tupv	189	1	(	(	-LRB-
cord-256187-ofp7tupv	189	2	Fig	Fig	NNP
cord-256187-ofp7tupv	189	3	.	.	NNP
cord-256187-ofp7tupv	189	4	4	4	CD
cord-256187-ofp7tupv	189	5	)	)	-RRB-
cord-256187-ofp7tupv	189	6	.	.	.
cord-256187-ofp7tupv	190	1	This	this	DT
cord-256187-ofp7tupv	190	2	study	study	NN
cord-256187-ofp7tupv	190	3	also	also	RB
cord-256187-ofp7tupv	190	4	revealed	reveal	VBD
cord-256187-ofp7tupv	190	5	that	that	IN
cord-256187-ofp7tupv	190	6	VP35	VP35	NNP
cord-256187-ofp7tupv	190	7	displays	display	VBZ
cord-256187-ofp7tupv	190	8	an	an	DT
cord-256187-ofp7tupv	190	9	IFN	IFN	NNP
cord-256187-ofp7tupv	190	10	inhibitory	inhibitory	JJ
cord-256187-ofp7tupv	190	11	activity	activity	NN
cord-256187-ofp7tupv	190	12	independent	independent	JJ
cord-256187-ofp7tupv	190	13	of	of	IN
cord-256187-ofp7tupv	190	14	its	-PRON-	PRP$
cord-256187-ofp7tupv	190	15	ability	ability	NN
cord-256187-ofp7tupv	190	16	to	to	TO
cord-256187-ofp7tupv	190	17	recognize	recognize	VB
cord-256187-ofp7tupv	190	18	dsRNA	dsrna	NN
cord-256187-ofp7tupv	190	19	,	,	,
cord-256187-ofp7tupv	190	20	and	and	CC
cord-256187-ofp7tupv	190	21	this	this	DT
cord-256187-ofp7tupv	190	22	activity	activity	NN
cord-256187-ofp7tupv	190	23	was	be	VBD
cord-256187-ofp7tupv	190	24	mapped	map	VBN
cord-256187-ofp7tupv	190	25	to	to	IN
cord-256187-ofp7tupv	190	26	the	the	DT
cord-256187-ofp7tupv	190	27	N	N	NNP
cord-256187-ofp7tupv	190	28	-	-	HYPH
cord-256187-ofp7tupv	190	29	terminus	terminus	NN
cord-256187-ofp7tupv	190	30	,	,	,
cord-256187-ofp7tupv	190	31	which	which	WDT
cord-256187-ofp7tupv	190	32	is	be	VBZ
cord-256187-ofp7tupv	190	33	essential	essential	JJ
cord-256187-ofp7tupv	190	34	for	for	IN
cord-256187-ofp7tupv	190	35	interactions	interaction	NNS
cord-256187-ofp7tupv	190	36	with	with	IN
cord-256187-ofp7tupv	190	37	IRF-7	IRF-7	NNP
cord-256187-ofp7tupv	190	38	and	and	CC
cord-256187-ofp7tupv	190	39	PIAS1	PIAS1	NNP
cord-256187-ofp7tupv	190	40	.	.	.
cord-256187-ofp7tupv	191	1	The	the	DT
cord-256187-ofp7tupv	191	2	interferon	interferon	NN
cord-256187-ofp7tupv	191	3	-	-	HYPH
cord-256187-ofp7tupv	191	4	inducible	inducible	JJ
cord-256187-ofp7tupv	191	5	dsRNA	dsrna	JJ
cord-256187-ofp7tupv	191	6	-	-	HYPH
cord-256187-ofp7tupv	191	7	dependent	dependent	JJ
cord-256187-ofp7tupv	191	8	protein	protein	NN
cord-256187-ofp7tupv	191	9	kinase	kinase	NN
cord-256187-ofp7tupv	191	10	(	(	-LRB-
cord-256187-ofp7tupv	191	11	PKR	PKR	NNP
cord-256187-ofp7tupv	191	12	)	)	-RRB-
cord-256187-ofp7tupv	191	13	recognizes	recognize	VBZ
cord-256187-ofp7tupv	191	14	dsRNA	dsrna	NN
cord-256187-ofp7tupv	191	15	produced	produce	VBN
cord-256187-ofp7tupv	191	16	in	in	IN
cord-256187-ofp7tupv	191	17	the	the	DT
cord-256187-ofp7tupv	191	18	context	context	NN
cord-256187-ofp7tupv	191	19	of	of	IN
cord-256187-ofp7tupv	191	20	infection	infection	NN
cord-256187-ofp7tupv	191	21	by	by	IN
cord-256187-ofp7tupv	191	22	RNA	RNA	NNP
cord-256187-ofp7tupv	191	23	viruses	virus	NNS
cord-256187-ofp7tupv	191	24	and	and	CC
cord-256187-ofp7tupv	191	25	DNA	dna	NN
cord-256187-ofp7tupv	191	26	viruses	virus	NNS
cord-256187-ofp7tupv	191	27	encoding	encode	VBG
cord-256187-ofp7tupv	191	28	opposite	opposite	RB
cord-256187-ofp7tupv	191	29	open	open	JJ
cord-256187-ofp7tupv	191	30	reading	reading	NN
cord-256187-ofp7tupv	191	31	frames	frame	NNS
cord-256187-ofp7tupv	191	32	from	from	IN
cord-256187-ofp7tupv	191	33	which	which	WDT
cord-256187-ofp7tupv	191	34	overlapping	overlap	VBG
cord-256187-ofp7tupv	191	35	mRNA	mrna	NN
cord-256187-ofp7tupv	191	36	sequences	sequence	NNS
cord-256187-ofp7tupv	191	37	are	be	VBP
cord-256187-ofp7tupv	191	38	generated	generate	VBN
cord-256187-ofp7tupv	192	1	(	(	-LRB-
cord-256187-ofp7tupv	192	2	George	George	NNP
cord-256187-ofp7tupv	192	3	et	et	NNP
cord-256187-ofp7tupv	192	4	al	al	NNP
cord-256187-ofp7tupv	192	5	.	.	NNP
cord-256187-ofp7tupv	192	6	,	,	,
cord-256187-ofp7tupv	192	7	2009	2009	CD
cord-256187-ofp7tupv	192	8	)	)	-RRB-
cord-256187-ofp7tupv	192	9	.	.	.
cord-256187-ofp7tupv	193	1	Subsequently	subsequently	RB
cord-256187-ofp7tupv	193	2	,	,	,
cord-256187-ofp7tupv	193	3	it	-PRON-	PRP
cord-256187-ofp7tupv	193	4	phosphorylates	phosphorylate	VBZ
cord-256187-ofp7tupv	193	5	the	the	DT
cord-256187-ofp7tupv	193	6	eukaryotic	eukaryotic	JJ
cord-256187-ofp7tupv	193	7	translation	translation	NN
cord-256187-ofp7tupv	193	8	initiation	initiation	NN
cord-256187-ofp7tupv	193	9	factor	factor	NN
cord-256187-ofp7tupv	193	10	2	2	CD
cord-256187-ofp7tupv	193	11	a	a	DT
cord-256187-ofp7tupv	193	12	(	(	-LRB-
cord-256187-ofp7tupv	193	13	eIF2a	eIF2a	NNP
cord-256187-ofp7tupv	193	14	)	)	-RRB-
cord-256187-ofp7tupv	193	15	,	,	,
cord-256187-ofp7tupv	193	16	which	which	WDT
cord-256187-ofp7tupv	193	17	results	result	VBZ
cord-256187-ofp7tupv	193	18	in	in	IN
cord-256187-ofp7tupv	193	19	the	the	DT
cord-256187-ofp7tupv	193	20	arrest	arrest	NN
cord-256187-ofp7tupv	193	21	of	of	IN
cord-256187-ofp7tupv	193	22	protein	protein	NN
cord-256187-ofp7tupv	193	23	synthesis	synthesis	NN
cord-256187-ofp7tupv	193	24	from	from	IN
cord-256187-ofp7tupv	193	25	cellular	cellular	JJ
cord-256187-ofp7tupv	193	26	and	and	CC
cord-256187-ofp7tupv	193	27	viral	viral	JJ
cord-256187-ofp7tupv	193	28	mRNAs	mRNAs	.
cord-256187-ofp7tupv	194	1	(	(	-LRB-
cord-256187-ofp7tupv	194	2	García	García	NNP
cord-256187-ofp7tupv	194	3	et	et	NNP
cord-256187-ofp7tupv	194	4	al	al	NNP
cord-256187-ofp7tupv	194	5	.	.	NNP
cord-256187-ofp7tupv	194	6	,	,	,
cord-256187-ofp7tupv	194	7	2007	2007	CD
cord-256187-ofp7tupv	194	8	)	)	-RRB-
cord-256187-ofp7tupv	194	9	.	.	.
cord-256187-ofp7tupv	195	1	In	in	IN
cord-256187-ofp7tupv	195	2	the	the	DT
cord-256187-ofp7tupv	195	3	context	context	NN
cord-256187-ofp7tupv	195	4	of	of	IN
cord-256187-ofp7tupv	195	5	EBOV	EBOV	NNP
cord-256187-ofp7tupv	195	6	infection	infection	NN
cord-256187-ofp7tupv	195	7	,	,	,
cord-256187-ofp7tupv	195	8	it	-PRON-	PRP
cord-256187-ofp7tupv	195	9	was	be	VBD
cord-256187-ofp7tupv	195	10	noted	note	VBN
cord-256187-ofp7tupv	195	11	that	that	IN
cord-256187-ofp7tupv	195	12	the	the	DT
cord-256187-ofp7tupv	195	13	expression	expression	NN
cord-256187-ofp7tupv	195	14	of	of	IN
cord-256187-ofp7tupv	195	15	VP35	VP35	NNP
cord-256187-ofp7tupv	195	16	and	and	CC
cord-256187-ofp7tupv	195	17	eIF-2a	eif-2a	NN
cord-256187-ofp7tupv	195	18	phosphorylation	phosphorylation	NN
cord-256187-ofp7tupv	195	19	inversely	inversely	RB
cord-256187-ofp7tupv	195	20	correlate	correlate	VBP
cord-256187-ofp7tupv	195	21	and	and	CC
cord-256187-ofp7tupv	195	22	that	that	IN
cord-256187-ofp7tupv	195	23	autophosphorylation	autophosphorylation	NN
cord-256187-ofp7tupv	195	24	of	of	IN
cord-256187-ofp7tupv	195	25	PKR	PKR	NNP
cord-256187-ofp7tupv	195	26	is	be	VBZ
cord-256187-ofp7tupv	195	27	disrupted	disrupt	VBN
cord-256187-ofp7tupv	195	28	in	in	IN
cord-256187-ofp7tupv	195	29	the	the	DT
cord-256187-ofp7tupv	195	30	presence	presence	NN
cord-256187-ofp7tupv	195	31	of	of	IN
cord-256187-ofp7tupv	195	32	VP35	VP35	NNP
cord-256187-ofp7tupv	195	33	(	(	-LRB-
cord-256187-ofp7tupv	195	34	Feng	Feng	NNP
cord-256187-ofp7tupv	195	35	et	et	FW
cord-256187-ofp7tupv	195	36	al	al	NNP
cord-256187-ofp7tupv	195	37	.	.	NNP
cord-256187-ofp7tupv	195	38	,	,	,
cord-256187-ofp7tupv	195	39	2007	2007	CD
cord-256187-ofp7tupv	195	40	)	)	-RRB-
cord-256187-ofp7tupv	195	41	.	.	.
cord-256187-ofp7tupv	196	1	Thus	thus	RB
cord-256187-ofp7tupv	196	2	,	,	,
cord-256187-ofp7tupv	196	3	VP35	VP35	NNP
cord-256187-ofp7tupv	196	4	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	196	5	PKR	PKR	NNP
cord-256187-ofp7tupv	196	6	activation	activation	NN
cord-256187-ofp7tupv	196	7	(	(	-LRB-
cord-256187-ofp7tupv	196	8	Fig	Fig	NNP
cord-256187-ofp7tupv	196	9	.	.	.
cord-256187-ofp7tupv	196	10	5	5	CD
cord-256187-ofp7tupv	196	11	)	)	-RRB-
cord-256187-ofp7tupv	196	12	.	.	.
cord-256187-ofp7tupv	197	1	In	in	IN
cord-256187-ofp7tupv	197	2	fact	fact	NN
cord-256187-ofp7tupv	197	3	,	,	,
cord-256187-ofp7tupv	197	4	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	197	5	was	be	VBD
cord-256187-ofp7tupv	197	6	shown	show	VBN
cord-256187-ofp7tupv	197	7	to	to	IN
cord-256187-ofp7tupv	197	8	not	not	RB
cord-256187-ofp7tupv	197	9	only	only	RB
cord-256187-ofp7tupv	197	10	block	block	VB
cord-256187-ofp7tupv	197	11	,	,	,
cord-256187-ofp7tupv	197	12	but	but	CC
cord-256187-ofp7tupv	197	13	to	to	TO
cord-256187-ofp7tupv	197	14	reverse	reverse	VB
cord-256187-ofp7tupv	197	15	activation	activation	NN
cord-256187-ofp7tupv	197	16	of	of	IN
cord-256187-ofp7tupv	197	17	PKR	PKR	NNP
cord-256187-ofp7tupv	197	18	(	(	-LRB-
cord-256187-ofp7tupv	197	19	Schumann	Schumann	NNP
cord-256187-ofp7tupv	197	20	et	et	NNP
cord-256187-ofp7tupv	197	21	al	al	NNP
cord-256187-ofp7tupv	197	22	.	.	NNP
cord-256187-ofp7tupv	197	23	,	,	,
cord-256187-ofp7tupv	197	24	2009	2009	CD
cord-256187-ofp7tupv	197	25	)	)	-RRB-
cord-256187-ofp7tupv	197	26	.	.	.
cord-256187-ofp7tupv	198	1	Feng	Feng	NNP
cord-256187-ofp7tupv	198	2	et	et	FW
cord-256187-ofp7tupv	198	3	al	al	NNP
cord-256187-ofp7tupv	198	4	.	.	.
cord-256187-ofp7tupv	199	1	(	(	-LRB-
cord-256187-ofp7tupv	199	2	2007	2007	CD
cord-256187-ofp7tupv	199	3	suggested	suggest	VBD
cord-256187-ofp7tupv	199	4	that	that	IN
cord-256187-ofp7tupv	199	5	VP35	VP35	NNP
cord-256187-ofp7tupv	199	6	inhibition	inhibition	NN
cord-256187-ofp7tupv	199	7	of	of	IN
cord-256187-ofp7tupv	199	8	PKR	PKR	NNP
cord-256187-ofp7tupv	199	9	might	may	MD
cord-256187-ofp7tupv	199	10	not	not	RB
cord-256187-ofp7tupv	199	11	involve	involve	VB
cord-256187-ofp7tupv	199	12	interactions	interaction	NNS
cord-256187-ofp7tupv	199	13	of	of	IN
cord-256187-ofp7tupv	199	14	these	these	DT
cord-256187-ofp7tupv	199	15	proteins	protein	NNS
cord-256187-ofp7tupv	199	16	and	and	CC
cord-256187-ofp7tupv	199	17	might	may	MD
cord-256187-ofp7tupv	199	18	not	not	RB
cord-256187-ofp7tupv	199	19	depend	depend	VB
cord-256187-ofp7tupv	199	20	on	on	IN
cord-256187-ofp7tupv	199	21	dsRNA	dsRNA	NNS
cord-256187-ofp7tupv	199	22	binding	bind	VBG
cord-256187-ofp7tupv	199	23	by	by	IN
cord-256187-ofp7tupv	199	24	VP35	VP35	NNP
cord-256187-ofp7tupv	199	25	.	.	.
cord-256187-ofp7tupv	200	1	Instead	instead	RB
cord-256187-ofp7tupv	200	2	,	,	,
cord-256187-ofp7tupv	200	3	a	a	DT
cord-256187-ofp7tupv	200	4	role	role	NN
cord-256187-ofp7tupv	200	5	of	of	IN
cord-256187-ofp7tupv	200	6	the	the	DT
cord-256187-ofp7tupv	200	7	N	n	CD
cord-256187-ofp7tupv	200	8	-	-	HYPH
cord-256187-ofp7tupv	200	9	terminal	terminal	NN
cord-256187-ofp7tupv	200	10	sequences	sequence	NNS
cord-256187-ofp7tupv	200	11	in	in	IN
cord-256187-ofp7tupv	200	12	VP35	VP35	NNP
cord-256187-ofp7tupv	200	13	was	be	VBD
cord-256187-ofp7tupv	200	14	suggested	suggest	VBN
cord-256187-ofp7tupv	200	15	.	.	.
cord-256187-ofp7tupv	201	1	Subsequent	subsequent	JJ
cord-256187-ofp7tupv	201	2	work	work	NN
cord-256187-ofp7tupv	201	3	by	by	IN
cord-256187-ofp7tupv	201	4	Schumann	Schumann	NNP
cord-256187-ofp7tupv	201	5	et	et	NNP
cord-256187-ofp7tupv	201	6	al	al	NNP
cord-256187-ofp7tupv	201	7	.	.	.
cord-256187-ofp7tupv	202	1	(	(	-LRB-
cord-256187-ofp7tupv	202	2	2009	2009	CD
cord-256187-ofp7tupv	202	3	)	)	-RRB-
cord-256187-ofp7tupv	202	4	indicates	indicate	VBZ
cord-256187-ofp7tupv	202	5	that	that	IN
cord-256187-ofp7tupv	202	6	mutations	mutation	NNS
cord-256187-ofp7tupv	202	7	in	in	IN
cord-256187-ofp7tupv	202	8	the	the	DT
cord-256187-ofp7tupv	202	9	IID	IID	NNP
cord-256187-ofp7tupv	202	10	can	can	MD
cord-256187-ofp7tupv	202	11	be	be	VB
cord-256187-ofp7tupv	202	12	sufficient	sufficient	JJ
cord-256187-ofp7tupv	202	13	to	to	TO
cord-256187-ofp7tupv	202	14	relief	relief	VB
cord-256187-ofp7tupv	202	15	the	the	DT
cord-256187-ofp7tupv	202	16	block	block	NN
cord-256187-ofp7tupv	202	17	to	to	IN
cord-256187-ofp7tupv	202	18	PKR	PKR	NNP
cord-256187-ofp7tupv	202	19	activation	activation	NN
cord-256187-ofp7tupv	202	20	imposed	impose	VBN
cord-256187-ofp7tupv	202	21	by	by	IN
cord-256187-ofp7tupv	202	22	VP35	VP35	NNP
cord-256187-ofp7tupv	202	23	and	and	CC
cord-256187-ofp7tupv	202	24	that	that	IN
cord-256187-ofp7tupv	202	25	PRK	PRK	NNP
cord-256187-ofp7tupv	202	26	antagonism	antagonism	NN
cord-256187-ofp7tupv	202	27	by	by	IN
cord-256187-ofp7tupv	202	28	VP35	VP35	NNP
cord-256187-ofp7tupv	202	29	is	be	VBZ
cord-256187-ofp7tupv	202	30	therefore	therefore	RB
cord-256187-ofp7tupv	202	31	functionally	functionally	RB
cord-256187-ofp7tupv	202	32	separate	separate	JJ
cord-256187-ofp7tupv	202	33	from	from	IN
cord-256187-ofp7tupv	202	34	dsRNA	dsrna	NN
cord-256187-ofp7tupv	202	35	binding	binding	NN
cord-256187-ofp7tupv	202	36	and	and	CC
cord-256187-ofp7tupv	202	37	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	202	38	inhibition	inhibition	NN
cord-256187-ofp7tupv	202	39	.	.	.
cord-256187-ofp7tupv	203	1	VP35	VP35	NNP
cord-256187-ofp7tupv	203	2	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	203	3	RNAi	RNAi	NNS
cord-256187-ofp7tupv	203	4	by	by	IN
cord-256187-ofp7tupv	203	5	targeting	target	VBG
cord-256187-ofp7tupv	203	6	the	the	DT
cord-256187-ofp7tupv	203	7	components	component	NNS
cord-256187-ofp7tupv	203	8	of	of	IN
cord-256187-ofp7tupv	203	9	the	the	DT
cord-256187-ofp7tupv	203	10	RNA	RNA	NNP
cord-256187-ofp7tupv	203	11	-	-	HYPH
cord-256187-ofp7tupv	203	12	induced	induce	VBN
cord-256187-ofp7tupv	203	13	silencing	silence	VBG
cord-256187-ofp7tupv	203	14	complex	complex	JJ
cord-256187-ofp7tupv	203	15	RNA	RNA	NNP
cord-256187-ofp7tupv	203	16	interference	interference	NN
cord-256187-ofp7tupv	203	17	allows	allow	VBZ
cord-256187-ofp7tupv	203	18	cells	cell	NNS
cord-256187-ofp7tupv	203	19	to	to	TO
cord-256187-ofp7tupv	203	20	specifically	specifically	RB
cord-256187-ofp7tupv	203	21	recognize	recognize	VB
cord-256187-ofp7tupv	203	22	and	and	CC
cord-256187-ofp7tupv	203	23	destroy	destroy	VB
cord-256187-ofp7tupv	203	24	viral	viral	JJ
cord-256187-ofp7tupv	203	25	RNA	RNA	NNP
cord-256187-ofp7tupv	203	26	and	and	CC
cord-256187-ofp7tupv	203	27	thus	thus	RB
cord-256187-ofp7tupv	203	28	to	to	TO
cord-256187-ofp7tupv	203	29	combat	combat	VB
cord-256187-ofp7tupv	203	30	viral	viral	JJ
cord-256187-ofp7tupv	203	31	infection	infection	NN
cord-256187-ofp7tupv	203	32	.	.	.
cord-256187-ofp7tupv	204	1	The	the	DT
cord-256187-ofp7tupv	204	2	observation	observation	NN
cord-256187-ofp7tupv	204	3	that	that	IN
cord-256187-ofp7tupv	204	4	several	several	JJ
cord-256187-ofp7tupv	204	5	viruses	virus	NNS
cord-256187-ofp7tupv	204	6	encode	encode	VBP
cord-256187-ofp7tupv	204	7	RNAi	RNAi	NNP
cord-256187-ofp7tupv	204	8	silencing	silence	VBG
cord-256187-ofp7tupv	204	9	suppressors	suppressor	NNS
cord-256187-ofp7tupv	204	10	(	(	-LRB-
cord-256187-ofp7tupv	204	11	RSS	RSS	NNP
cord-256187-ofp7tupv	204	12	)	)	-RRB-
cord-256187-ofp7tupv	204	13	,	,	,
cord-256187-ofp7tupv	204	14	like	like	IN
cord-256187-ofp7tupv	204	15	the	the	DT
cord-256187-ofp7tupv	204	16	NS1	ns1	NN
cord-256187-ofp7tupv	204	17	protein	protein	NN
cord-256187-ofp7tupv	204	18	of	of	IN
cord-256187-ofp7tupv	204	19	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	204	20	or	or	CC
cord-256187-ofp7tupv	204	21	the	the	DT
cord-256187-ofp7tupv	204	22	Tat	Tat	NNP
cord-256187-ofp7tupv	204	23	protein	protein	NN
cord-256187-ofp7tupv	204	24	of	of	IN
cord-256187-ofp7tupv	204	25	the	the	DT
cord-256187-ofp7tupv	204	26	human	human	JJ
cord-256187-ofp7tupv	204	27	immunodeficiency	immunodeficiency	NN
cord-256187-ofp7tupv	204	28	virus	virus	NN
cord-256187-ofp7tupv	204	29	type	type	NN
cord-256187-ofp7tupv	204	30	1	1	CD
cord-256187-ofp7tupv	204	31	(	(	-LRB-
cord-256187-ofp7tupv	204	32	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	204	33	)	)	-RRB-
cord-256187-ofp7tupv	204	34	,	,	,
cord-256187-ofp7tupv	204	35	underlines	underline	VBZ
cord-256187-ofp7tupv	204	36	the	the	DT
cord-256187-ofp7tupv	204	37	potency	potency	NN
cord-256187-ofp7tupv	204	38	of	of	IN
cord-256187-ofp7tupv	204	39	this	this	DT
cord-256187-ofp7tupv	204	40	cellular	cellular	JJ
cord-256187-ofp7tupv	204	41	defence	defence	NN
cord-256187-ofp7tupv	204	42	mechanism	mechanism	NN
cord-256187-ofp7tupv	204	43	(	(	-LRB-
cord-256187-ofp7tupv	204	44	Bivalkar	Bivalkar	NNP
cord-256187-ofp7tupv	204	45	-	-	HYPH
cord-256187-ofp7tupv	204	46	Mehla	Mehla	NNP
cord-256187-ofp7tupv	204	47	et	et	FW
cord-256187-ofp7tupv	204	48	al	al	NNP
cord-256187-ofp7tupv	204	49	.	.	NNP
cord-256187-ofp7tupv	204	50	,	,	,
cord-256187-ofp7tupv	204	51	2011	2011	CD
cord-256187-ofp7tupv	204	52	)	)	-RRB-
cord-256187-ofp7tupv	204	53	.	.	.
cord-256187-ofp7tupv	205	1	Haasnoot	Haasnoot	NNP
cord-256187-ofp7tupv	205	2	et	et	IN
cord-256187-ofp7tupv	205	3	al	al	NNP
cord-256187-ofp7tupv	205	4	.	.	.
cord-256187-ofp7tupv	206	1	(	(	-LRB-
cord-256187-ofp7tupv	206	2	2007	2007	CD
cord-256187-ofp7tupv	206	3	)	)	-RRB-
cord-256187-ofp7tupv	206	4	demonstrated	demonstrate	VBD
cord-256187-ofp7tupv	206	5	that	that	IN
cord-256187-ofp7tupv	206	6	EBOV	EBOV	NNP
cord-256187-ofp7tupv	206	7	VP35	VP35	NNP
cord-256187-ofp7tupv	206	8	is	be	VBZ
cord-256187-ofp7tupv	206	9	an	an	DT
cord-256187-ofp7tupv	206	10	RSS	RSS	NNP
cord-256187-ofp7tupv	206	11	,	,	,
cord-256187-ofp7tupv	206	12	which	which	WDT
cord-256187-ofp7tupv	206	13	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	206	14	shRNA	shrna	JJ
cord-256187-ofp7tupv	206	15	-	-	HYPH
cord-256187-ofp7tupv	206	16	mediated	mediate	VBN
cord-256187-ofp7tupv	206	17	suppression	suppression	NN
cord-256187-ofp7tupv	206	18	of	of	IN
cord-256187-ofp7tupv	206	19	reporter	reporter	NN
cord-256187-ofp7tupv	206	20	gene	gene	NN
cord-256187-ofp7tupv	206	21	expression	expression	NN
cord-256187-ofp7tupv	206	22	and	and	CC
cord-256187-ofp7tupv	206	23	rescues	rescue	VBZ
cord-256187-ofp7tupv	206	24	production	production	NN
cord-256187-ofp7tupv	206	25	of	of	IN
cord-256187-ofp7tupv	206	26	tat	tat	JJ
cord-256187-ofp7tupv	206	27	-	-	HYPH
cord-256187-ofp7tupv	206	28	defective	defective	JJ
cord-256187-ofp7tupv	206	29	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	206	30	from	from	IN
cord-256187-ofp7tupv	206	31	suppression	suppression	NN
cord-256187-ofp7tupv	206	32	by	by	IN
cord-256187-ofp7tupv	206	33	RNAi	RNAi	NNS
cord-256187-ofp7tupv	206	34	.	.	.
cord-256187-ofp7tupv	207	1	The	the	DT
cord-256187-ofp7tupv	207	2	RSS	RSS	NNP
cord-256187-ofp7tupv	207	3	activity	activity	NN
cord-256187-ofp7tupv	207	4	of	of	IN
cord-256187-ofp7tupv	207	5	VP35	VP35	NNP
cord-256187-ofp7tupv	207	6	was	be	VBD
cord-256187-ofp7tupv	207	7	dependent	dependent	JJ
cord-256187-ofp7tupv	207	8	on	on	IN
cord-256187-ofp7tupv	207	9	its	-PRON-	PRP$
cord-256187-ofp7tupv	207	10	dsRNA	dsrna	JJ
cord-256187-ofp7tupv	207	11	-	-	HYPH
cord-256187-ofp7tupv	207	12	binding	bind	VBG
cord-256187-ofp7tupv	207	13	capability	capability	NN
cord-256187-ofp7tupv	207	14	(	(	-LRB-
cord-256187-ofp7tupv	207	15	Haasnoot	Haasnoot	NNP
cord-256187-ofp7tupv	207	16	et	et	NNP
cord-256187-ofp7tupv	207	17	al	al	NNP
cord-256187-ofp7tupv	207	18	.	.	NNP
cord-256187-ofp7tupv	207	19	,	,	,
cord-256187-ofp7tupv	207	20	2007	2007	CD
cord-256187-ofp7tupv	207	21	)	)	-RRB-
cord-256187-ofp7tupv	207	22	,	,	,
cord-256187-ofp7tupv	207	23	suggesting	suggest	VBG
cord-256187-ofp7tupv	207	24	that	that	IN
cord-256187-ofp7tupv	207	25	VP35	VP35	NNP
cord-256187-ofp7tupv	207	26	may	may	MD
cord-256187-ofp7tupv	207	27	sequester	sequester	VB
cord-256187-ofp7tupv	207	28	and	and	CC
cord-256187-ofp7tupv	207	29	protect	protect	VB
cord-256187-ofp7tupv	207	30	dsRNA	dsrna	NN
cord-256187-ofp7tupv	207	31	from	from	IN
cord-256187-ofp7tupv	207	32	recognition	recognition	NN
cord-256187-ofp7tupv	207	33	by	by	IN
cord-256187-ofp7tupv	207	34	dicer	dicer	NN
cord-256187-ofp7tupv	207	35	,	,	,
cord-256187-ofp7tupv	207	36	a	a	DT
cord-256187-ofp7tupv	207	37	central	central	JJ
cord-256187-ofp7tupv	207	38	molecule	molecule	NN
cord-256187-ofp7tupv	207	39	of	of	IN
cord-256187-ofp7tupv	207	40	the	the	DT
cord-256187-ofp7tupv	207	41	RNAi	RNAi	NNP
cord-256187-ofp7tupv	207	42	pathway	pathway	NN
cord-256187-ofp7tupv	207	43	(	(	-LRB-
cord-256187-ofp7tupv	207	44	Fig	Fig	NNP
cord-256187-ofp7tupv	207	45	.	.	NNP
cord-256187-ofp7tupv	207	46	4	4	CD
cord-256187-ofp7tupv	207	47	)	)	-RRB-
cord-256187-ofp7tupv	207	48	.	.	.
cord-256187-ofp7tupv	208	1	However	however	RB
cord-256187-ofp7tupv	208	2	,	,	,
cord-256187-ofp7tupv	208	3	a	a	DT
cord-256187-ofp7tupv	208	4	subsequent	subsequent	JJ
cord-256187-ofp7tupv	208	5	study	study	NN
cord-256187-ofp7tupv	208	6	demonstrated	demonstrate	VBD
cord-256187-ofp7tupv	208	7	that	that	IN
cord-256187-ofp7tupv	208	8	VP35	VP35	NNP
cord-256187-ofp7tupv	208	9	interacts	interact	VBZ
cord-256187-ofp7tupv	208	10	with	with	IN
cord-256187-ofp7tupv	208	11	components	component	NNS
cord-256187-ofp7tupv	208	12	of	of	IN
cord-256187-ofp7tupv	208	13	the	the	DT
cord-256187-ofp7tupv	208	14	RNA	RNA	NNP
cord-256187-ofp7tupv	208	15	-	-	HYPH
cord-256187-ofp7tupv	208	16	induced	induce	VBN
cord-256187-ofp7tupv	208	17	silencing	silence	VBG
cord-256187-ofp7tupv	208	18	complex	complex	NN
cord-256187-ofp7tupv	208	19	(	(	-LRB-
cord-256187-ofp7tupv	208	20	RISC	RISC	NNP
cord-256187-ofp7tupv	208	21	)	)	-RRB-
cord-256187-ofp7tupv	208	22	independent	independent	NN
cord-256187-ofp7tupv	208	23	of	of	IN
cord-256187-ofp7tupv	208	24	the	the	DT
cord-256187-ofp7tupv	208	25	presence	presence	NN
cord-256187-ofp7tupv	208	26	of	of	IN
cord-256187-ofp7tupv	208	27	siRNA	siRNA	NNP
cord-256187-ofp7tupv	208	28	(	(	-LRB-
cord-256187-ofp7tupv	208	29	Fabozzi	Fabozzi	NNP
cord-256187-ofp7tupv	208	30	et	et	NNP
cord-256187-ofp7tupv	208	31	al	al	NNP
cord-256187-ofp7tupv	208	32	.	.	NNP
cord-256187-ofp7tupv	208	33	,	,	,
cord-256187-ofp7tupv	208	34	2011	2011	CD
cord-256187-ofp7tupv	208	35	)	)	-RRB-
cord-256187-ofp7tupv	208	36	.	.	.
cord-256187-ofp7tupv	209	1	Specifically	specifically	RB
cord-256187-ofp7tupv	209	2	,	,	,
cord-256187-ofp7tupv	209	3	VP35	VP35	NNP
cord-256187-ofp7tupv	209	4	was	be	VBD
cord-256187-ofp7tupv	209	5	found	find	VBN
cord-256187-ofp7tupv	209	6	to	to	TO
cord-256187-ofp7tupv	209	7	interact	interact	VB
cord-256187-ofp7tupv	209	8	with	with	IN
cord-256187-ofp7tupv	209	9	the	the	DT
cord-256187-ofp7tupv	209	10	two	two	CD
cord-256187-ofp7tupv	209	11	dsRNA	dsrna	JJ
cord-256187-ofp7tupv	209	12	-	-	HYPH
cord-256187-ofp7tupv	209	13	binding	bind	VBG
cord-256187-ofp7tupv	209	14	proteins	protein	NNS
cord-256187-ofp7tupv	209	15	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	209	16	trans	trans	JJ
cord-256187-ofp7tupv	209	17	-	-	JJ
cord-256187-ofp7tupv	209	18	activation	activation	NNP
cord-256187-ofp7tupv	209	19	response	response	NN
cord-256187-ofp7tupv	209	20	RNA	rna	NN
cord-256187-ofp7tupv	209	21	-	-	HYPH
cord-256187-ofp7tupv	209	22	binding	bind	VBG
cord-256187-ofp7tupv	209	23	protein	protein	NN
cord-256187-ofp7tupv	209	24	(	(	-LRB-
cord-256187-ofp7tupv	209	25	TRBP	TRBP	NNP
cord-256187-ofp7tupv	209	26	)	)	-RRB-
cord-256187-ofp7tupv	209	27	and	and	CC
cord-256187-ofp7tupv	209	28	protein	protein	NN
cord-256187-ofp7tupv	209	29	activator	activator	NN
cord-256187-ofp7tupv	209	30	of	of	IN
cord-256187-ofp7tupv	209	31	PKR	PKR	NNP
cord-256187-ofp7tupv	209	32	(	(	-LRB-
cord-256187-ofp7tupv	209	33	PACT	PACT	NNP
cord-256187-ofp7tupv	209	34	)	)	-RRB-
cord-256187-ofp7tupv	209	35	,	,	,
cord-256187-ofp7tupv	209	36	which	which	WDT
cord-256187-ofp7tupv	209	37	are	be	VBP
cord-256187-ofp7tupv	209	38	part	part	NN
cord-256187-ofp7tupv	209	39	of	of	IN
cord-256187-ofp7tupv	209	40	the	the	DT
cord-256187-ofp7tupv	209	41	RISC	RISC	NNP
cord-256187-ofp7tupv	209	42	complex	complex	NN
cord-256187-ofp7tupv	209	43	,	,	,
cord-256187-ofp7tupv	209	44	but	but	CC
cord-256187-ofp7tupv	209	45	not	not	RB
cord-256187-ofp7tupv	209	46	directly	directly	RB
cord-256187-ofp7tupv	209	47	with	with	IN
cord-256187-ofp7tupv	209	48	dicer	dicer	NN
cord-256187-ofp7tupv	209	49	(	(	-LRB-
cord-256187-ofp7tupv	209	50	Fabozzi	Fabozzi	NNP
cord-256187-ofp7tupv	209	51	et	et	NNP
cord-256187-ofp7tupv	209	52	al	al	NNP
cord-256187-ofp7tupv	209	53	.	.	NNP
cord-256187-ofp7tupv	209	54	,	,	,
cord-256187-ofp7tupv	209	55	2011	2011	CD
cord-256187-ofp7tupv	209	56	)	)	-RRB-
cord-256187-ofp7tupv	209	57	.	.	.
cord-256187-ofp7tupv	210	1	In	in	IN
cord-256187-ofp7tupv	210	2	addition	addition	NN
cord-256187-ofp7tupv	210	3	,	,	,
cord-256187-ofp7tupv	210	4	evidence	evidence	NN
cord-256187-ofp7tupv	210	5	was	be	VBD
cord-256187-ofp7tupv	210	6	presented	present	VBN
cord-256187-ofp7tupv	210	7	that	that	IN
cord-256187-ofp7tupv	210	8	also	also	RB
cord-256187-ofp7tupv	210	9	VP30	VP30	NNP
cord-256187-ofp7tupv	210	10	and	and	CC
cord-256187-ofp7tupv	210	11	VP40	VP40	NNP
cord-256187-ofp7tupv	210	12	act	act	VBP
cord-256187-ofp7tupv	210	13	as	as	IN
cord-256187-ofp7tupv	210	14	RSS	RSS	NNP
cord-256187-ofp7tupv	210	15	,	,	,
cord-256187-ofp7tupv	210	16	and	and	CC
cord-256187-ofp7tupv	210	17	VP30	VP30	NNP
cord-256187-ofp7tupv	210	18	like	like	IN
cord-256187-ofp7tupv	210	19	VP35	VP35	NNP
cord-256187-ofp7tupv	210	20	was	be	VBD
cord-256187-ofp7tupv	210	21	shown	show	VBN
cord-256187-ofp7tupv	210	22	to	to	TO
cord-256187-ofp7tupv	210	23	bind	bind	VB
cord-256187-ofp7tupv	210	24	to	to	IN
cord-256187-ofp7tupv	210	25	components	component	NNS
cord-256187-ofp7tupv	210	26	of	of	IN
cord-256187-ofp7tupv	210	27	the	the	DT
cord-256187-ofp7tupv	210	28	RISC	RISC	NNP
cord-256187-ofp7tupv	210	29	complex	complex	NN
cord-256187-ofp7tupv	210	30	,	,	,
cord-256187-ofp7tupv	210	31	while	while	IN
cord-256187-ofp7tupv	210	32	no	no	DT
cord-256187-ofp7tupv	210	33	such	such	JJ
cord-256187-ofp7tupv	210	34	interactions	interaction	NNS
cord-256187-ofp7tupv	210	35	were	be	VBD
cord-256187-ofp7tupv	210	36	seen	see	VBN
cord-256187-ofp7tupv	210	37	for	for	IN
cord-256187-ofp7tupv	210	38	VP40	VP40	NNP
cord-256187-ofp7tupv	210	39	,	,	,
cord-256187-ofp7tupv	210	40	which	which	WDT
cord-256187-ofp7tupv	210	41	might	may	MD
cord-256187-ofp7tupv	210	42	employ	employ	VB
cord-256187-ofp7tupv	210	43	a	a	DT
cord-256187-ofp7tupv	210	44	different	different	JJ
cord-256187-ofp7tupv	210	45	strategy	strategy	NN
cord-256187-ofp7tupv	210	46	to	to	TO
cord-256187-ofp7tupv	210	47	inhibit	inhibit	VB
cord-256187-ofp7tupv	210	48	RNAi	RNAi	NNS
cord-256187-ofp7tupv	210	49	(	(	-LRB-
cord-256187-ofp7tupv	210	50	Fabozzi	Fabozzi	NNP
cord-256187-ofp7tupv	210	51	et	et	NNP
cord-256187-ofp7tupv	210	52	al	al	NNP
cord-256187-ofp7tupv	210	53	.	.	NNP
cord-256187-ofp7tupv	210	54	,	,	,
cord-256187-ofp7tupv	210	55	2011	2011	CD
cord-256187-ofp7tupv	210	56	)	)	-RRB-
cord-256187-ofp7tupv	210	57	.	.	.
cord-256187-ofp7tupv	211	1	The	the	DT
cord-256187-ofp7tupv	211	2	tetherin	tetherin	NN
cord-256187-ofp7tupv	211	3	protein	protein	NN
cord-256187-ofp7tupv	211	4	(	(	-LRB-
cord-256187-ofp7tupv	211	5	HM1.24	HM1.24	NNP
cord-256187-ofp7tupv	211	6	,	,	,
cord-256187-ofp7tupv	211	7	BST-2	BST-2	NNP
cord-256187-ofp7tupv	211	8	,	,	,
cord-256187-ofp7tupv	211	9	CD317	CD317	NNP
cord-256187-ofp7tupv	211	10	)	)	-RRB-
cord-256187-ofp7tupv	211	11	was	be	VBD
cord-256187-ofp7tupv	211	12	identified	identify	VBN
cord-256187-ofp7tupv	211	13	as	as	IN
cord-256187-ofp7tupv	211	14	a	a	DT
cord-256187-ofp7tupv	211	15	type	type	NN
cord-256187-ofp7tupv	211	16	I	-PRON-	PRP
cord-256187-ofp7tupv	211	17	interferon	interferon	NN
cord-256187-ofp7tupv	211	18	-	-	HYPH
cord-256187-ofp7tupv	211	19	inducible	inducible	JJ
cord-256187-ofp7tupv	211	20	host	host	NN
cord-256187-ofp7tupv	211	21	cellular	cellular	JJ
cord-256187-ofp7tupv	211	22	factor	factor	NN
cord-256187-ofp7tupv	211	23	,	,	,
cord-256187-ofp7tupv	211	24	which	which	WDT
cord-256187-ofp7tupv	211	25	restricts	restrict	VBZ
cord-256187-ofp7tupv	211	26	release	release	NN
cord-256187-ofp7tupv	211	27	of	of	IN
cord-256187-ofp7tupv	211	28	progeny	progeny	JJ
cord-256187-ofp7tupv	211	29	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	211	30	particles	particle	NNS
cord-256187-ofp7tupv	211	31	from	from	IN
cord-256187-ofp7tupv	211	32	infected	infected	JJ
cord-256187-ofp7tupv	211	33	cells	cell	NNS
cord-256187-ofp7tupv	211	34	(	(	-LRB-
cord-256187-ofp7tupv	211	35	Neil	Neil	NNP
cord-256187-ofp7tupv	211	36	et	et	NNP
cord-256187-ofp7tupv	211	37	al	al	NNP
cord-256187-ofp7tupv	211	38	.	.	NNP
cord-256187-ofp7tupv	211	39	,	,	,
cord-256187-ofp7tupv	211	40	2008	2008	CD
cord-256187-ofp7tupv	211	41	;	;	.
cord-256187-ofp7tupv	212	1	Van	Van	NNP
cord-256187-ofp7tupv	212	2	Damme	Damme	NNP
cord-256187-ofp7tupv	212	3	et	et	NNP
cord-256187-ofp7tupv	212	4	al	al	NNP
cord-256187-ofp7tupv	212	5	.	.	NNP
cord-256187-ofp7tupv	212	6	,	,	,
cord-256187-ofp7tupv	212	7	2008	2008	CD
cord-256187-ofp7tupv	212	8	)	)	-RRB-
cord-256187-ofp7tupv	212	9	.	.	.
cord-256187-ofp7tupv	213	1	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	213	2	is	be	VBZ
cord-256187-ofp7tupv	213	3	counteracted	counteract	VBN
cord-256187-ofp7tupv	213	4	by	by	IN
cord-256187-ofp7tupv	213	5	the	the	DT
cord-256187-ofp7tupv	213	6	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	213	7	accessory	accessory	NN
cord-256187-ofp7tupv	213	8	protein	protein	NN
cord-256187-ofp7tupv	213	9	Vpu	Vpu	NNP
cord-256187-ofp7tupv	213	10	(	(	-LRB-
cord-256187-ofp7tupv	213	11	viral	viral	JJ
cord-256187-ofp7tupv	213	12	protein	protein	NN
cord-256187-ofp7tupv	213	13	u	u	NNP
cord-256187-ofp7tupv	213	14	)	)	-RRB-
cord-256187-ofp7tupv	213	15	,	,	,
cord-256187-ofp7tupv	213	16	which	which	WDT
cord-256187-ofp7tupv	213	17	allows	allow	VBZ
cord-256187-ofp7tupv	213	18	efficient	efficient	JJ
cord-256187-ofp7tupv	213	19	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	213	20	release	release	NN
cord-256187-ofp7tupv	213	21	form	form	NN
cord-256187-ofp7tupv	213	22	tetherin	tetherin	NN
cord-256187-ofp7tupv	213	23	-	-	HYPH
cord-256187-ofp7tupv	213	24	expressing	express	VBG
cord-256187-ofp7tupv	213	25	cells	cell	NNS
cord-256187-ofp7tupv	213	26	(	(	-LRB-
cord-256187-ofp7tupv	213	27	Neil	Neil	NNP
cord-256187-ofp7tupv	213	28	et	et	NNP
cord-256187-ofp7tupv	213	29	al	al	NNP
cord-256187-ofp7tupv	213	30	.	.	NNP
cord-256187-ofp7tupv	213	31	,	,	,
cord-256187-ofp7tupv	213	32	2008	2008	CD
cord-256187-ofp7tupv	213	33	;	;	:
cord-256187-ofp7tupv	213	34	Van	Van	NNP
cord-256187-ofp7tupv	213	35	Damme	Damme	NNP
cord-256187-ofp7tupv	213	36	et	et	NNP
cord-256187-ofp7tupv	213	37	al	al	NNP
cord-256187-ofp7tupv	213	38	.	.	NNP
cord-256187-ofp7tupv	213	39	,	,	,
cord-256187-ofp7tupv	213	40	2008	2008	CD
cord-256187-ofp7tupv	213	41	)	)	-RRB-
cord-256187-ofp7tupv	213	42	.	.	.
cord-256187-ofp7tupv	214	1	The	the	DT
cord-256187-ofp7tupv	214	2	antiviral	antiviral	JJ
cord-256187-ofp7tupv	214	3	action	action	NN
cord-256187-ofp7tupv	214	4	of	of	IN
cord-256187-ofp7tupv	214	5	tetherin	tetherin	NNP
cord-256187-ofp7tupv	214	6	is	be	VBZ
cord-256187-ofp7tupv	214	7	not	not	RB
cord-256187-ofp7tupv	214	8	limited	limited	JJ
cord-256187-ofp7tupv	214	9	to	to	IN
cord-256187-ofp7tupv	214	10	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	214	11	;	;	:
cord-256187-ofp7tupv	214	12	several	several	JJ
cord-256187-ofp7tupv	214	13	recent	recent	JJ
cord-256187-ofp7tupv	214	14	studies	study	NNS
cord-256187-ofp7tupv	214	15	found	find	VBD
cord-256187-ofp7tupv	214	16	that	that	IN
cord-256187-ofp7tupv	214	17	tetherin	tetherin	NNP
cord-256187-ofp7tupv	214	18	restricts	restrict	VBZ
cord-256187-ofp7tupv	214	19	release	release	NN
cord-256187-ofp7tupv	214	20	of	of	IN
cord-256187-ofp7tupv	214	21	VLPs	vlp	NNS
cord-256187-ofp7tupv	214	22	and	and	CC
cord-256187-ofp7tupv	214	23	progeny	progeny	NN
cord-256187-ofp7tupv	214	24	particles	particle	NNS
cord-256187-ofp7tupv	214	25	of	of	IN
cord-256187-ofp7tupv	214	26	several	several	JJ
cord-256187-ofp7tupv	214	27	enveloped	envelop	VBN
cord-256187-ofp7tupv	214	28	viruses	virus	NNS
cord-256187-ofp7tupv	214	29	,	,	,
cord-256187-ofp7tupv	214	30	including	include	VBG
cord-256187-ofp7tupv	214	31	members	member	NNS
cord-256187-ofp7tupv	214	32	of	of	IN
cord-256187-ofp7tupv	214	33	the	the	DT
cord-256187-ofp7tupv	214	34	Retroviridae	Retroviridae	NNP
cord-256187-ofp7tupv	214	35	,	,	,
cord-256187-ofp7tupv	214	36	Arenaviridae	Arenaviridae	NNP
cord-256187-ofp7tupv	214	37	,	,	,
cord-256187-ofp7tupv	214	38	Paramyxoviridae	Paramyxoviridae	NNP
cord-256187-ofp7tupv	214	39	,	,	,
cord-256187-ofp7tupv	214	40	Filoviridae	Filoviridae	NNP
cord-256187-ofp7tupv	214	41	,	,	,
cord-256187-ofp7tupv	214	42	Rhabdoviridae	Rhabdoviridae	NNP
cord-256187-ofp7tupv	214	43	and	and	CC
cord-256187-ofp7tupv	214	44	Herpesviridae	Herpesviridae	NNP
cord-256187-ofp7tupv	214	45	families	family	NNS
cord-256187-ofp7tupv	214	46	(	(	-LRB-
cord-256187-ofp7tupv	215	1	Jouvenet	Jouvenet	NNP
cord-256187-ofp7tupv	215	2	et	et	NNP
cord-256187-ofp7tupv	215	3	al	al	NNP
cord-256187-ofp7tupv	215	4	.	.	NNP
cord-256187-ofp7tupv	215	5	,	,	,
cord-256187-ofp7tupv	216	1	Fig	Fig	NNP
cord-256187-ofp7tupv	216	2	.	.	NNP
cord-256187-ofp7tupv	216	3	5	5	CD
cord-256187-ofp7tupv	216	4	.	.	.
cord-256187-ofp7tupv	217	1	Countermeasures	countermeasure	NNS
cord-256187-ofp7tupv	217	2	of	of	IN
cord-256187-ofp7tupv	217	3	Ebola	Ebola	NNP
cord-256187-ofp7tupv	217	4	virus	virus	NN
cord-256187-ofp7tupv	217	5	against	against	IN
cord-256187-ofp7tupv	217	6	IFN	IFN	NNP
cord-256187-ofp7tupv	217	7	-	-	HYPH
cord-256187-ofp7tupv	217	8	induced	induce	VBN
cord-256187-ofp7tupv	217	9	antiviral	antiviral	JJ
cord-256187-ofp7tupv	217	10	proteins	protein	NNS
cord-256187-ofp7tupv	217	11	.	.	.
cord-256187-ofp7tupv	218	1	Ebola	Ebola	NNP
cord-256187-ofp7tupv	218	2	virus	virus	NN
cord-256187-ofp7tupv	218	3	infection	infection	NN
cord-256187-ofp7tupv	218	4	commences	commence	VBZ
cord-256187-ofp7tupv	218	5	with	with	IN
cord-256187-ofp7tupv	218	6	viral	viral	JJ
cord-256187-ofp7tupv	218	7	uptake	uptake	NN
cord-256187-ofp7tupv	218	8	and	and	CC
cord-256187-ofp7tupv	218	9	transport	transport	NN
cord-256187-ofp7tupv	218	10	of	of	IN
cord-256187-ofp7tupv	218	11	virions	virion	NNS
cord-256187-ofp7tupv	218	12	into	into	IN
cord-256187-ofp7tupv	218	13	endosomal	endosomal	NNP
cord-256187-ofp7tupv	218	14	compartments	compartment	NNS
cord-256187-ofp7tupv	218	15	,	,	,
cord-256187-ofp7tupv	218	16	where	where	WRB
cord-256187-ofp7tupv	218	17	the	the	DT
cord-256187-ofp7tupv	218	18	EBOV	EBOV	NNP
cord-256187-ofp7tupv	218	19	-	-	HYPH
cord-256187-ofp7tupv	218	20	GP	GP	NNP
cord-256187-ofp7tupv	218	21	is	be	VBZ
cord-256187-ofp7tupv	218	22	activated	activate	VBN
cord-256187-ofp7tupv	218	23	by	by	IN
cord-256187-ofp7tupv	218	24	cathepsins	cathepsin	NNS
cord-256187-ofp7tupv	218	25	.	.	.
cord-256187-ofp7tupv	219	1	Subsequently	subsequently	RB
cord-256187-ofp7tupv	219	2	,	,	,
cord-256187-ofp7tupv	219	3	GP	GP	NNP
cord-256187-ofp7tupv	219	4	mediates	mediate	VBZ
cord-256187-ofp7tupv	219	5	fusion	fusion	NN
cord-256187-ofp7tupv	219	6	of	of	IN
cord-256187-ofp7tupv	219	7	the	the	DT
cord-256187-ofp7tupv	219	8	viral	viral	JJ
cord-256187-ofp7tupv	219	9	envelope	envelope	NN
cord-256187-ofp7tupv	219	10	with	with	IN
cord-256187-ofp7tupv	219	11	the	the	DT
cord-256187-ofp7tupv	219	12	endosomal	endosomal	NNP
cord-256187-ofp7tupv	219	13	membrane	membrane	NN
cord-256187-ofp7tupv	219	14	,	,	,
cord-256187-ofp7tupv	219	15	allowing	allow	VBG
cord-256187-ofp7tupv	219	16	release	release	NN
cord-256187-ofp7tupv	219	17	of	of	IN
cord-256187-ofp7tupv	219	18	the	the	DT
cord-256187-ofp7tupv	219	19	viral	viral	JJ
cord-256187-ofp7tupv	219	20	genome	genome	NN
cord-256187-ofp7tupv	219	21	into	into	IN
cord-256187-ofp7tupv	219	22	the	the	DT
cord-256187-ofp7tupv	219	23	cytosol	cytosol	NN
cord-256187-ofp7tupv	219	24	.	.	.
cord-256187-ofp7tupv	220	1	Subsequently	subsequently	RB
cord-256187-ofp7tupv	220	2	,	,	,
cord-256187-ofp7tupv	220	3	the	the	DT
cord-256187-ofp7tupv	220	4	viral	viral	JJ
cord-256187-ofp7tupv	220	5	genome	genome	NN
cord-256187-ofp7tupv	220	6	is	be	VBZ
cord-256187-ofp7tupv	220	7	transcribed	transcribe	VBN
cord-256187-ofp7tupv	220	8	into	into	IN
cord-256187-ofp7tupv	220	9	mRNAs	mrnas	PRP
cord-256187-ofp7tupv	220	10	and	and	CC
cord-256187-ofp7tupv	220	11	replicated	replicate	VBN
cord-256187-ofp7tupv	220	12	.	.	.
cord-256187-ofp7tupv	221	1	Viral	viral	JJ
cord-256187-ofp7tupv	221	2	proteins	protein	NNS
cord-256187-ofp7tupv	221	3	are	be	VBP
cord-256187-ofp7tupv	221	4	translated	translate	VBN
cord-256187-ofp7tupv	221	5	and	and	CC
cord-256187-ofp7tupv	221	6	transported	transport	VBN
cord-256187-ofp7tupv	221	7	to	to	IN
cord-256187-ofp7tupv	221	8	the	the	DT
cord-256187-ofp7tupv	221	9	cellular	cellular	JJ
cord-256187-ofp7tupv	221	10	membrane	membrane	NN
cord-256187-ofp7tupv	221	11	for	for	IN
cord-256187-ofp7tupv	221	12	assembly	assembly	NN
cord-256187-ofp7tupv	221	13	of	of	IN
cord-256187-ofp7tupv	221	14	new	new	JJ
cord-256187-ofp7tupv	221	15	particles	particle	NNS
cord-256187-ofp7tupv	221	16	,	,	,
cord-256187-ofp7tupv	221	17	which	which	WDT
cord-256187-ofp7tupv	221	18	eventually	eventually	RB
cord-256187-ofp7tupv	221	19	bud	bud	VBP
cord-256187-ofp7tupv	221	20	from	from	IN
cord-256187-ofp7tupv	221	21	the	the	DT
cord-256187-ofp7tupv	221	22	host	host	NN
cord-256187-ofp7tupv	221	23	cell	cell	NN
cord-256187-ofp7tupv	221	24	membrane	membrane	NN
cord-256187-ofp7tupv	221	25	.	.	.
cord-256187-ofp7tupv	222	1	Virus	virus	NN
cord-256187-ofp7tupv	222	2	entry	entry	NN
cord-256187-ofp7tupv	222	3	is	be	VBZ
cord-256187-ofp7tupv	222	4	inhibited	inhibit	VBN
cord-256187-ofp7tupv	222	5	by	by	IN
cord-256187-ofp7tupv	222	6	the	the	DT
cord-256187-ofp7tupv	222	7	IFN	IFN	NNP
cord-256187-ofp7tupv	222	8	-	-	HYPH
cord-256187-ofp7tupv	222	9	induced	induce	VBN
cord-256187-ofp7tupv	222	10	IFITM	IFITM	NNP
cord-256187-ofp7tupv	222	11	proteins	protein	NNS
cord-256187-ofp7tupv	222	12	.	.	.
cord-256187-ofp7tupv	223	1	The	the	DT
cord-256187-ofp7tupv	223	2	exact	exact	JJ
cord-256187-ofp7tupv	223	3	step	step	NN
cord-256187-ofp7tupv	223	4	that	that	WDT
cord-256187-ofp7tupv	223	5	is	be	VBZ
cord-256187-ofp7tupv	223	6	blocked	block	VBN
cord-256187-ofp7tupv	223	7	by	by	IN
cord-256187-ofp7tupv	223	8	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	223	9	remains	remain	VBZ
cord-256187-ofp7tupv	223	10	to	to	TO
cord-256187-ofp7tupv	223	11	be	be	VB
cord-256187-ofp7tupv	223	12	defined	define	VBN
cord-256187-ofp7tupv	223	13	.	.	.
cord-256187-ofp7tupv	224	1	The	the	DT
cord-256187-ofp7tupv	224	2	protein	protein	NN
cord-256187-ofp7tupv	224	3	kinase	kinase	NN
cord-256187-ofp7tupv	224	4	R	r	NN
cord-256187-ofp7tupv	224	5	,	,	,
cord-256187-ofp7tupv	224	6	which	which	WDT
cord-256187-ofp7tupv	224	7	senses	sense	VBZ
cord-256187-ofp7tupv	224	8	dsRNA	dsrna	NN
cord-256187-ofp7tupv	224	9	intermediates	intermediate	NNS
cord-256187-ofp7tupv	224	10	of	of	IN
cord-256187-ofp7tupv	224	11	viral	viral	JJ
cord-256187-ofp7tupv	224	12	replication	replication	NN
cord-256187-ofp7tupv	224	13	,	,	,
cord-256187-ofp7tupv	224	14	phosphorylates	phosphorylate	VBZ
cord-256187-ofp7tupv	224	15	the	the	DT
cord-256187-ofp7tupv	224	16	translation	translation	NN
cord-256187-ofp7tupv	224	17	initiation	initiation	NN
cord-256187-ofp7tupv	224	18	factor	factor	NN
cord-256187-ofp7tupv	224	19	eIF2a	eIF2a	NNP
cord-256187-ofp7tupv	224	20	,	,	,
cord-256187-ofp7tupv	224	21	which	which	WDT
cord-256187-ofp7tupv	224	22	results	result	VBZ
cord-256187-ofp7tupv	224	23	in	in	IN
cord-256187-ofp7tupv	224	24	the	the	DT
cord-256187-ofp7tupv	224	25	arrest	arrest	NN
cord-256187-ofp7tupv	224	26	of	of	IN
cord-256187-ofp7tupv	224	27	translation	translation	NN
cord-256187-ofp7tupv	224	28	of	of	IN
cord-256187-ofp7tupv	224	29	viral	viral	JJ
cord-256187-ofp7tupv	224	30	and	and	CC
cord-256187-ofp7tupv	224	31	cellular	cellular	JJ
cord-256187-ofp7tupv	224	32	mRNAs	mrna	NNS
cord-256187-ofp7tupv	224	33	.	.	.
cord-256187-ofp7tupv	225	1	The	the	DT
cord-256187-ofp7tupv	225	2	tetherin	tetherin	NN
cord-256187-ofp7tupv	225	3	protein	protein	NN
cord-256187-ofp7tupv	225	4	tethers	tether	NNS
cord-256187-ofp7tupv	225	5	budding	bud	VBG
cord-256187-ofp7tupv	225	6	EBOV	EBOV	NNP
cord-256187-ofp7tupv	225	7	-	-	HYPH
cord-256187-ofp7tupv	225	8	like	like	JJ
cord-256187-ofp7tupv	225	9	particles	particle	NNS
cord-256187-ofp7tupv	225	10	to	to	IN
cord-256187-ofp7tupv	225	11	the	the	DT
cord-256187-ofp7tupv	225	12	cell	cell	NN
cord-256187-ofp7tupv	225	13	surface	surface	NN
cord-256187-ofp7tupv	225	14	and	and	CC
cord-256187-ofp7tupv	225	15	is	be	VBZ
cord-256187-ofp7tupv	225	16	counteracted	counteract	VBN
cord-256187-ofp7tupv	225	17	by	by	IN
cord-256187-ofp7tupv	225	18	EBOV	EBOV	NNP
cord-256187-ofp7tupv	225	19	-	-	HYPH
cord-256187-ofp7tupv	225	20	GP	GP	NNP
cord-256187-ofp7tupv	225	21	.	.	.
cord-256187-ofp7tupv	226	1	GP	GP	NNP
cord-256187-ofp7tupv	226	2	,	,	,
cord-256187-ofp7tupv	226	3	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	226	4	;	;	:
cord-256187-ofp7tupv	226	5	VP	VP	NNP
cord-256187-ofp7tupv	226	6	,	,	,
cord-256187-ofp7tupv	226	7	viral	viral	JJ
cord-256187-ofp7tupv	226	8	protein	protein	NN
cord-256187-ofp7tupv	226	9	;	;	:
cord-256187-ofp7tupv	226	10	L	L	NNP
cord-256187-ofp7tupv	226	11	,	,	,
cord-256187-ofp7tupv	226	12	RNA	RNA	NNP
cord-256187-ofp7tupv	226	13	-	-	HYPH
cord-256187-ofp7tupv	226	14	dependent	dependent	JJ
cord-256187-ofp7tupv	226	15	RNA	RNA	NNP
cord-256187-ofp7tupv	226	16	polymerase	polymerase	NN
cord-256187-ofp7tupv	226	17	;	;	:
cord-256187-ofp7tupv	226	18	NP	NP	NNP
cord-256187-ofp7tupv	226	19	,	,	,
cord-256187-ofp7tupv	226	20	nucleoprotein	nucleoprotein	NNP
cord-256187-ofp7tupv	226	21	;	;	:
cord-256187-ofp7tupv	226	22	IFITM	IFITM	NNP
cord-256187-ofp7tupv	226	23	,	,	,
cord-256187-ofp7tupv	226	24	IFN	IFN	NNP
cord-256187-ofp7tupv	226	25	-	-	HYPH
cord-256187-ofp7tupv	226	26	induced	induce	VBN
cord-256187-ofp7tupv	226	27	transmembrane	transmembrane	NN
cord-256187-ofp7tupv	226	28	protein	protein	NN
cord-256187-ofp7tupv	226	29	;	;	:
cord-256187-ofp7tupv	226	30	PKR	PKR	NNP
cord-256187-ofp7tupv	226	31	,	,	,
cord-256187-ofp7tupv	226	32	dsRNA	dsrna	JJ
cord-256187-ofp7tupv	226	33	-	-	HYPH
cord-256187-ofp7tupv	226	34	dependent	dependent	JJ
cord-256187-ofp7tupv	226	35	protein	protein	NN
cord-256187-ofp7tupv	226	36	kinase	kinase	NN
cord-256187-ofp7tupv	226	37	;	;	:
cord-256187-ofp7tupv	226	38	EBOV	EBOV	NNP
cord-256187-ofp7tupv	226	39	-	-	HYPH
cord-256187-ofp7tupv	226	40	GP	GP	NNP
cord-256187-ofp7tupv	226	41	,	,	,
cord-256187-ofp7tupv	226	42	Ebola	Ebola	NNP
cord-256187-ofp7tupv	226	43	virus	virus	NN
cord-256187-ofp7tupv	226	44	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	226	45	.	.	.
cord-256187-ofp7tupv	226	46	2009	2009	CD
cord-256187-ofp7tupv	226	47	;	;	.
cord-256187-ofp7tupv	227	1	Mansouri	Mansouri	NNP
cord-256187-ofp7tupv	227	2	et	et	NNP
cord-256187-ofp7tupv	227	3	al	al	NNP
cord-256187-ofp7tupv	227	4	.	.	.
cord-256187-ofp7tupv	228	1	,	,	,
cord-256187-ofp7tupv	228	2	2009	2009	CD
cord-256187-ofp7tupv	228	3	;	;	:
cord-256187-ofp7tupv	228	4	Sakuma	Sakuma	NNP
cord-256187-ofp7tupv	228	5	et	et	FW
cord-256187-ofp7tupv	228	6	al	al	NNP
cord-256187-ofp7tupv	228	7	.	.	.
cord-256187-ofp7tupv	229	1	,	,	,
cord-256187-ofp7tupv	229	2	2009	2009	CD
cord-256187-ofp7tupv	229	3	;	;	:
cord-256187-ofp7tupv	229	4	Pardieu	Pardieu	NNP
cord-256187-ofp7tupv	229	5	et	et	NNP
cord-256187-ofp7tupv	229	6	al	al	NNP
cord-256187-ofp7tupv	229	7	.	.	NNP
cord-256187-ofp7tupv	229	8	,	,	,
cord-256187-ofp7tupv	229	9	2010	2010	CD
cord-256187-ofp7tupv	229	10	;	;	:
cord-256187-ofp7tupv	229	11	Radoshitzky	Radoshitzky	NNP
cord-256187-ofp7tupv	229	12	et	et	NNP
cord-256187-ofp7tupv	229	13	al	al	NNP
cord-256187-ofp7tupv	229	14	.	.	NNP
cord-256187-ofp7tupv	229	15	,	,	,
cord-256187-ofp7tupv	229	16	2010	2010	CD
cord-256187-ofp7tupv	229	17	;	;	.
cord-256187-ofp7tupv	230	1	Weidner	Weidner	NNP
cord-256187-ofp7tupv	230	2	et	et	NNP
cord-256187-ofp7tupv	230	3	al	al	NNP
cord-256187-ofp7tupv	230	4	.	.	NNP
cord-256187-ofp7tupv	230	5	,	,	,
cord-256187-ofp7tupv	230	6	2010	2010	CD
cord-256187-ofp7tupv	231	1	;	;	:
cord-256187-ofp7tupv	231	2	Watanabe	Watanabe	NNP
cord-256187-ofp7tupv	231	3	et	et	NNP
cord-256187-ofp7tupv	231	4	al	al	NNP
cord-256187-ofp7tupv	231	5	.	.	NNP
cord-256187-ofp7tupv	231	6	,	,	,
cord-256187-ofp7tupv	231	7	2011	2011	CD
cord-256187-ofp7tupv	231	8	;	;	:
cord-256187-ofp7tupv	231	9	Yondola	Yondola	NNP
cord-256187-ofp7tupv	231	10	et	et	NNP
cord-256187-ofp7tupv	231	11	al	al	NNP
cord-256187-ofp7tupv	231	12	.	.	NNP
cord-256187-ofp7tupv	231	13	,	,	,
cord-256187-ofp7tupv	231	14	2011	2011	CD
cord-256187-ofp7tupv	231	15	)	)	-RRB-
cord-256187-ofp7tupv	232	1	(	(	-LRB-
cord-256187-ofp7tupv	232	2	Fig	Fig	NNP
cord-256187-ofp7tupv	232	3	.	.	NNP
cord-256187-ofp7tupv	232	4	5	5	CD
cord-256187-ofp7tupv	232	5	)	)	-RRB-
cord-256187-ofp7tupv	232	6	.	.	.
cord-256187-ofp7tupv	233	1	The	the	DT
cord-256187-ofp7tupv	233	2	broad	broad	JJ
cord-256187-ofp7tupv	233	3	spectrum	spectrum	NN
cord-256187-ofp7tupv	233	4	antiviral	antiviral	JJ
cord-256187-ofp7tupv	233	5	action	action	NN
cord-256187-ofp7tupv	233	6	of	of	IN
cord-256187-ofp7tupv	233	7	tetherin	tetherin	NNP
cord-256187-ofp7tupv	233	8	is	be	VBZ
cord-256187-ofp7tupv	233	9	intimately	intimately	RB
cord-256187-ofp7tupv	233	10	linked	link	VBN
cord-256187-ofp7tupv	233	11	to	to	IN
cord-256187-ofp7tupv	233	12	its	-PRON-	PRP$
cord-256187-ofp7tupv	233	13	unusual	unusual	JJ
cord-256187-ofp7tupv	233	14	structural	structural	JJ
cord-256187-ofp7tupv	233	15	organization	organization	NN
cord-256187-ofp7tupv	233	16	.	.	.
cord-256187-ofp7tupv	234	1	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	234	2	encodes	encode	VBZ
cord-256187-ofp7tupv	234	3	a	a	DT
cord-256187-ofp7tupv	234	4	short	short	JJ
cord-256187-ofp7tupv	234	5	cytoplasmic	cytoplasmic	JJ
cord-256187-ofp7tupv	234	6	domain	domain	NN
cord-256187-ofp7tupv	234	7	at	at	IN
cord-256187-ofp7tupv	234	8	its	-PRON-	PRP$
cord-256187-ofp7tupv	234	9	N	n	CD
cord-256187-ofp7tupv	234	10	-	-	HYPH
cord-256187-ofp7tupv	234	11	terminus	terminus	NN
cord-256187-ofp7tupv	234	12	,	,	,
cord-256187-ofp7tupv	234	13	followed	follow	VBN
cord-256187-ofp7tupv	234	14	by	by	IN
cord-256187-ofp7tupv	234	15	a	a	DT
cord-256187-ofp7tupv	234	16	single	single	JJ
cord-256187-ofp7tupv	234	17	transmembrane	transmembrane	NN
cord-256187-ofp7tupv	234	18	(	(	-LRB-
cord-256187-ofp7tupv	234	19	TM	TM	NNP
cord-256187-ofp7tupv	234	20	)	)	-RRB-
cord-256187-ofp7tupv	234	21	domain	domain	NN
cord-256187-ofp7tupv	234	22	,	,	,
cord-256187-ofp7tupv	234	23	an	an	DT
cord-256187-ofp7tupv	234	24	extracellular	extracellular	JJ
cord-256187-ofp7tupv	234	25	coiled	coil	VBN
cord-256187-ofp7tupv	234	26	-	-	HYPH
cord-256187-ofp7tupv	234	27	coil	coil	NN
cord-256187-ofp7tupv	234	28	region	region	NN
cord-256187-ofp7tupv	234	29	and	and	CC
cord-256187-ofp7tupv	234	30	a	a	DT
cord-256187-ofp7tupv	234	31	C	c	NN
cord-256187-ofp7tupv	234	32	-	-	HYPH
cord-256187-ofp7tupv	234	33	terminal	terminal	NN
cord-256187-ofp7tupv	234	34	glycosylphosphatidylinositol	glycosylphosphatidylinositol	NN
cord-256187-ofp7tupv	234	35	(	(	-LRB-
cord-256187-ofp7tupv	234	36	GPI	GPI	NNP
cord-256187-ofp7tupv	234	37	)	)	-RRB-
cord-256187-ofp7tupv	234	38	anchor	anchor	NN
cord-256187-ofp7tupv	235	1	(	(	-LRB-
cord-256187-ofp7tupv	235	2	Kupzig	Kupzig	NNP
cord-256187-ofp7tupv	235	3	et	et	NNP
cord-256187-ofp7tupv	235	4	al	al	NNP
cord-256187-ofp7tupv	235	5	.	.	NNP
cord-256187-ofp7tupv	235	6	,	,	,
cord-256187-ofp7tupv	235	7	2003	2003	CD
cord-256187-ofp7tupv	235	8	)	)	-RRB-
cord-256187-ofp7tupv	235	9	.	.	.
cord-256187-ofp7tupv	236	1	Thus	thus	RB
cord-256187-ofp7tupv	236	2	,	,	,
cord-256187-ofp7tupv	236	3	the	the	DT
cord-256187-ofp7tupv	236	4	protein	protein	NN
cord-256187-ofp7tupv	236	5	spans	span	VBZ
cord-256187-ofp7tupv	236	6	the	the	DT
cord-256187-ofp7tupv	236	7	membrane	membrane	NN
cord-256187-ofp7tupv	236	8	twice	twice	RB
cord-256187-ofp7tupv	236	9	and	and	CC
cord-256187-ofp7tupv	236	10	is	be	VBZ
cord-256187-ofp7tupv	236	11	able	able	JJ
cord-256187-ofp7tupv	236	12	to	to	TO
cord-256187-ofp7tupv	236	13	insert	insert	VB
cord-256187-ofp7tupv	236	14	one	one	CD
cord-256187-ofp7tupv	236	15	end	end	NN
cord-256187-ofp7tupv	236	16	into	into	IN
cord-256187-ofp7tupv	236	17	the	the	DT
cord-256187-ofp7tupv	236	18	cellular	cellular	JJ
cord-256187-ofp7tupv	236	19	membrane	membrane	NN
cord-256187-ofp7tupv	236	20	and	and	CC
cord-256187-ofp7tupv	236	21	the	the	DT
cord-256187-ofp7tupv	236	22	other	other	JJ
cord-256187-ofp7tupv	236	23	end	end	NN
cord-256187-ofp7tupv	236	24	into	into	IN
cord-256187-ofp7tupv	236	25	the	the	DT
cord-256187-ofp7tupv	236	26	viral	viral	JJ
cord-256187-ofp7tupv	236	27	envelope	envelope	NN
cord-256187-ofp7tupv	236	28	.	.	.
cord-256187-ofp7tupv	237	1	By	by	IN
cord-256187-ofp7tupv	237	2	this	this	DT
cord-256187-ofp7tupv	237	3	mechanism	mechanism	NN
cord-256187-ofp7tupv	237	4	,	,	,
cord-256187-ofp7tupv	237	5	tetherin	tetherin	NNP
cord-256187-ofp7tupv	237	6	retains	retain	VBZ
cord-256187-ofp7tupv	237	7	budding	bud	VBG
cord-256187-ofp7tupv	237	8	virions	virion	NNS
cord-256187-ofp7tupv	237	9	at	at	IN
cord-256187-ofp7tupv	237	10	the	the	DT
cord-256187-ofp7tupv	237	11	surface	surface	NN
cord-256187-ofp7tupv	237	12	of	of	IN
cord-256187-ofp7tupv	237	13	the	the	DT
cord-256187-ofp7tupv	237	14	infected	infected	JJ
cord-256187-ofp7tupv	237	15	cell	cell	NN
cord-256187-ofp7tupv	237	16	and	and	CC
cord-256187-ofp7tupv	237	17	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	237	18	their	-PRON-	PRP$
cord-256187-ofp7tupv	237	19	transmission	transmission	NN
cord-256187-ofp7tupv	237	20	to	to	IN
cord-256187-ofp7tupv	237	21	new	new	JJ
cord-256187-ofp7tupv	237	22	target	target	NN
cord-256187-ofp7tupv	237	23	cells	cell	NNS
cord-256187-ofp7tupv	238	1	(	(	-LRB-
cord-256187-ofp7tupv	238	2	Perez	Perez	NNP
cord-256187-ofp7tupv	238	3	-	-	HYPH
cord-256187-ofp7tupv	238	4	Caballero	Caballero	NNP
cord-256187-ofp7tupv	238	5	et	et	NNP
cord-256187-ofp7tupv	238	6	al	al	NNP
cord-256187-ofp7tupv	238	7	.	.	.
cord-256187-ofp7tupv	239	1	,	,	,
cord-256187-ofp7tupv	239	2	2009	2009	CD
cord-256187-ofp7tupv	239	3	;	;	:
cord-256187-ofp7tupv	239	4	Hammonds	Hammonds	NNP
cord-256187-ofp7tupv	239	5	et	et	NNP
cord-256187-ofp7tupv	239	6	al	al	NNP
cord-256187-ofp7tupv	239	7	.	.	NNP
cord-256187-ofp7tupv	239	8	,	,	,
cord-256187-ofp7tupv	239	9	2010	2010	CD
cord-256187-ofp7tupv	239	10	)	)	-RRB-
cord-256187-ofp7tupv	239	11	.	.	.
cord-256187-ofp7tupv	240	1	An	an	DT
cord-256187-ofp7tupv	240	2	artificially	artificially	RB
cord-256187-ofp7tupv	240	3	constructed	construct	VBN
cord-256187-ofp7tupv	240	4	tetherin	tetherin	NNS
cord-256187-ofp7tupv	240	5	,	,	,
cord-256187-ofp7tupv	240	6	which	which	WDT
cord-256187-ofp7tupv	240	7	displays	display	VBZ
cord-256187-ofp7tupv	240	8	the	the	DT
cord-256187-ofp7tupv	240	9	same	same	JJ
cord-256187-ofp7tupv	240	10	topology	topology	NN
cord-256187-ofp7tupv	240	11	as	as	IN
cord-256187-ofp7tupv	240	12	the	the	DT
cord-256187-ofp7tupv	240	13	original	original	JJ
cord-256187-ofp7tupv	240	14	molecule	molecule	NN
cord-256187-ofp7tupv	240	15	,	,	,
cord-256187-ofp7tupv	240	16	but	but	CC
cord-256187-ofp7tupv	240	17	is	be	VBZ
cord-256187-ofp7tupv	240	18	assembled	assemble	VBN
cord-256187-ofp7tupv	240	19	from	from	IN
cord-256187-ofp7tupv	240	20	completely	completely	RB
cord-256187-ofp7tupv	240	21	unrelated	unrelated	JJ
cord-256187-ofp7tupv	240	22	sequences	sequence	NNS
cord-256187-ofp7tupv	240	23	,	,	,
cord-256187-ofp7tupv	240	24	is	be	VBZ
cord-256187-ofp7tupv	240	25	able	able	JJ
cord-256187-ofp7tupv	240	26	to	to	TO
cord-256187-ofp7tupv	240	27	inhibit	inhibit	VB
cord-256187-ofp7tupv	240	28	virus	virus	NN
cord-256187-ofp7tupv	240	29	spread	spread	VBN
cord-256187-ofp7tupv	240	30	as	as	RB
cord-256187-ofp7tupv	240	31	well	well	RB
cord-256187-ofp7tupv	240	32	,	,	,
cord-256187-ofp7tupv	240	33	confirming	confirm	VBG
cord-256187-ofp7tupv	240	34	that	that	IN
cord-256187-ofp7tupv	240	35	it	-PRON-	PRP
cord-256187-ofp7tupv	240	36	is	be	VBZ
cord-256187-ofp7tupv	240	37	tetherin	tetherin	NNP
cord-256187-ofp7tupv	240	38	's	's	POS
cord-256187-ofp7tupv	240	39	unusual	unusual	JJ
cord-256187-ofp7tupv	240	40	architecture	architecture	NN
cord-256187-ofp7tupv	240	41	that	that	WDT
cord-256187-ofp7tupv	240	42	is	be	VBZ
cord-256187-ofp7tupv	240	43	responsible	responsible	JJ
cord-256187-ofp7tupv	240	44	for	for	IN
cord-256187-ofp7tupv	240	45	tethering	tether	VBG
cord-256187-ofp7tupv	240	46	virions	virion	NNS
cord-256187-ofp7tupv	240	47	to	to	IN
cord-256187-ofp7tupv	240	48	cells	cell	NNS
cord-256187-ofp7tupv	241	1	(	(	-LRB-
cord-256187-ofp7tupv	241	2	Perez	Perez	NNP
cord-256187-ofp7tupv	241	3	-	-	HYPH
cord-256187-ofp7tupv	241	4	Caballero	Caballero	NNP
cord-256187-ofp7tupv	241	5	et	et	NNP
cord-256187-ofp7tupv	241	6	al	al	NNP
cord-256187-ofp7tupv	241	7	.	.	NNP
cord-256187-ofp7tupv	241	8	,	,	,
cord-256187-ofp7tupv	241	9	2009	2009	CD
cord-256187-ofp7tupv	241	10	)	)	-RRB-
cord-256187-ofp7tupv	241	11	.	.	.
cord-256187-ofp7tupv	242	1	Antagonism	antagonism	NN
cord-256187-ofp7tupv	242	2	of	of	IN
cord-256187-ofp7tupv	242	3	tetherin	tetherin	NNP
cord-256187-ofp7tupv	242	4	is	be	VBZ
cord-256187-ofp7tupv	242	5	not	not	RB
cord-256187-ofp7tupv	242	6	limited	limited	JJ
cord-256187-ofp7tupv	242	7	to	to	IN
cord-256187-ofp7tupv	242	8	Vpu	Vpu	NNP
cord-256187-ofp7tupv	242	9	.	.	.
cord-256187-ofp7tupv	243	1	HIV-2	hiv-2	NN
cord-256187-ofp7tupv	243	2	uses	use	VBZ
cord-256187-ofp7tupv	243	3	its	-PRON-	PRP$
cord-256187-ofp7tupv	243	4	envelope	envelope	NN
cord-256187-ofp7tupv	243	5	(	(	-LRB-
cord-256187-ofp7tupv	243	6	Env	Env	NNP
cord-256187-ofp7tupv	243	7	)	)	-RRB-
cord-256187-ofp7tupv	243	8	protein	protein	NN
cord-256187-ofp7tupv	243	9	to	to	TO
cord-256187-ofp7tupv	243	10	counteract	counteract	VB
cord-256187-ofp7tupv	243	11	tetherin	tetherin	NNS
cord-256187-ofp7tupv	243	12	(	(	-LRB-
cord-256187-ofp7tupv	243	13	Le	Le	NNP
cord-256187-ofp7tupv	243	14	Tortorec	Tortorec	NNP
cord-256187-ofp7tupv	243	15	and	and	CC
cord-256187-ofp7tupv	243	16	Neil	Neil	NNP
cord-256187-ofp7tupv	243	17	,	,	,
cord-256187-ofp7tupv	243	18	2009	2009	CD
cord-256187-ofp7tupv	243	19	)	)	-RRB-
cord-256187-ofp7tupv	243	20	,	,	,
cord-256187-ofp7tupv	243	21	while	while	IN
cord-256187-ofp7tupv	243	22	the	the	DT
cord-256187-ofp7tupv	243	23	simian	simian	JJ
cord-256187-ofp7tupv	243	24	immunodeficiency	immunodeficiency	NN
cord-256187-ofp7tupv	243	25	virus	virus	NN
cord-256187-ofp7tupv	243	26	(	(	-LRB-
cord-256187-ofp7tupv	243	27	SIV	SIV	NNP
cord-256187-ofp7tupv	243	28	)	)	-RRB-
cord-256187-ofp7tupv	243	29	uses	use	VBZ
cord-256187-ofp7tupv	243	30	either	either	CC
cord-256187-ofp7tupv	243	31	the	the	DT
cord-256187-ofp7tupv	243	32	accessory	accessory	NN
cord-256187-ofp7tupv	243	33	protein	protein	NN
cord-256187-ofp7tupv	243	34	Nef	Nef	NNP
cord-256187-ofp7tupv	243	35	or	or	CC
cord-256187-ofp7tupv	243	36	Vpu	Vpu	NNP
cord-256187-ofp7tupv	243	37	or	or	CC
cord-256187-ofp7tupv	243	38	Env	Env	NNP
cord-256187-ofp7tupv	243	39	,	,	,
cord-256187-ofp7tupv	243	40	depending	depend	VBG
cord-256187-ofp7tupv	243	41	on	on	IN
cord-256187-ofp7tupv	243	42	the	the	DT
cord-256187-ofp7tupv	243	43	origin	origin	NN
cord-256187-ofp7tupv	243	44	of	of	IN
cord-256187-ofp7tupv	243	45	the	the	DT
cord-256187-ofp7tupv	243	46	virus	virus	NN
cord-256187-ofp7tupv	244	1	(	(	-LRB-
cord-256187-ofp7tupv	244	2	Gupta	Gupta	NNP
cord-256187-ofp7tupv	244	3	et	et	NNP
cord-256187-ofp7tupv	244	4	al	al	NNP
cord-256187-ofp7tupv	244	5	.	.	.
cord-256187-ofp7tupv	245	1	,	,	,
cord-256187-ofp7tupv	245	2	2009	2009	CD
cord-256187-ofp7tupv	245	3	;	;	:
cord-256187-ofp7tupv	245	4	Sauter	Sauter	NNP
cord-256187-ofp7tupv	245	5	et	et	NNP
cord-256187-ofp7tupv	245	6	al	al	NNP
cord-256187-ofp7tupv	245	7	.	.	NNP
cord-256187-ofp7tupv	245	8	,	,	,
cord-256187-ofp7tupv	245	9	2009	2009	CD
cord-256187-ofp7tupv	245	10	)	)	-RRB-
cord-256187-ofp7tupv	245	11	.	.	.
cord-256187-ofp7tupv	246	1	The	the	DT
cord-256187-ofp7tupv	246	2	Kaposi	Kaposi	NNP
cord-256187-ofp7tupv	246	3	's	's	POS
cord-256187-ofp7tupv	246	4	sarcoma	sarcoma	NN
cord-256187-ofp7tupv	246	5	-	-	HYPH
cord-256187-ofp7tupv	246	6	associated	associate	VBN
cord-256187-ofp7tupv	246	7	herpes	herpes	NNP
cord-256187-ofp7tupv	246	8	virus	virus	NN
cord-256187-ofp7tupv	246	9	encodes	encode	VBZ
cord-256187-ofp7tupv	246	10	the	the	DT
cord-256187-ofp7tupv	246	11	E3	e3	NN
cord-256187-ofp7tupv	246	12	ubiquitin	ubiquitin	NN
cord-256187-ofp7tupv	246	13	ligase	ligase	NN
cord-256187-ofp7tupv	246	14	K5	K5	NNP
cord-256187-ofp7tupv	246	15	as	as	IN
cord-256187-ofp7tupv	246	16	a	a	DT
cord-256187-ofp7tupv	246	17	tetherin	tetherin	NN
cord-256187-ofp7tupv	246	18	antagonist	antagonist	NN
cord-256187-ofp7tupv	246	19	(	(	-LRB-
cord-256187-ofp7tupv	246	20	Mansouri	Mansouri	NNP
cord-256187-ofp7tupv	246	21	et	et	NNP
cord-256187-ofp7tupv	246	22	al	al	NNP
cord-256187-ofp7tupv	246	23	.	.	NNP
cord-256187-ofp7tupv	246	24	,	,	,
cord-256187-ofp7tupv	246	25	2009	2009	CD
cord-256187-ofp7tupv	246	26	)	)	-RRB-
cord-256187-ofp7tupv	246	27	.	.	.
cord-256187-ofp7tupv	247	1	For	for	IN
cord-256187-ofp7tupv	247	2	the	the	DT
cord-256187-ofp7tupv	247	3	EBOV	EBOV	NNP
cord-256187-ofp7tupv	247	4	,	,	,
cord-256187-ofp7tupv	247	5	the	the	DT
cord-256187-ofp7tupv	247	6	GP	GP	NNP
cord-256187-ofp7tupv	247	7	1,2	1,2	CD
cord-256187-ofp7tupv	247	8	serves	serve	VBZ
cord-256187-ofp7tupv	247	9	as	as	IN
cord-256187-ofp7tupv	247	10	tetherin	tetherin	NNP
cord-256187-ofp7tupv	247	11	antagonist	antagonist	NN
cord-256187-ofp7tupv	247	12	(	(	-LRB-
cord-256187-ofp7tupv	247	13	Kaletsky	Kaletsky	NNP
cord-256187-ofp7tupv	247	14	et	et	NNP
cord-256187-ofp7tupv	247	15	al	al	NNP
cord-256187-ofp7tupv	247	16	.	.	NNP
cord-256187-ofp7tupv	247	17	,	,	,
cord-256187-ofp7tupv	247	18	2009	2009	CD
cord-256187-ofp7tupv	247	19	)	)	-RRB-
cord-256187-ofp7tupv	247	20	.	.	.
cord-256187-ofp7tupv	248	1	This	this	DT
cord-256187-ofp7tupv	248	2	ability	ability	NN
cord-256187-ofp7tupv	248	3	of	of	IN
cord-256187-ofp7tupv	248	4	GP	GP	NNP
cord-256187-ofp7tupv	248	5	1,2	1,2	CD
cord-256187-ofp7tupv	248	6	is	be	VBZ
cord-256187-ofp7tupv	248	7	conserved	conserve	VBN
cord-256187-ofp7tupv	248	8	between	between	IN
cord-256187-ofp7tupv	248	9	the	the	DT
cord-256187-ofp7tupv	248	10	GPs	gps	NNS
cord-256187-ofp7tupv	248	11	of	of	IN
cord-256187-ofp7tupv	248	12	the	the	DT
cord-256187-ofp7tupv	248	13	different	different	JJ
cord-256187-ofp7tupv	248	14	EBOV	EBOV	NNP
cord-256187-ofp7tupv	248	15	species	specie	NNS
cord-256187-ofp7tupv	248	16	(	(	-LRB-
cord-256187-ofp7tupv	248	17	Zaire	Zaire	NNP
cord-256187-ofp7tupv	248	18	,	,	,
cord-256187-ofp7tupv	248	19	Sudan	Sudan	NNP
cord-256187-ofp7tupv	248	20	,	,	,
cord-256187-ofp7tupv	248	21	Côte	Côte	NNP
cord-256187-ofp7tupv	248	22	d'Ivoire	d'Ivoire	NNP
cord-256187-ofp7tupv	248	23	and	and	CC
cord-256187-ofp7tupv	248	24	Reston	Reston	NNP
cord-256187-ofp7tupv	248	25	)	)	-RRB-
cord-256187-ofp7tupv	248	26	,	,	,
cord-256187-ofp7tupv	248	27	the	the	DT
cord-256187-ofp7tupv	248	28	proposed	propose	VBN
cord-256187-ofp7tupv	248	29	species	species	NN
cord-256187-ofp7tupv	248	30	BEBOV	BEBOV	NNP
cord-256187-ofp7tupv	248	31	and	and	CC
cord-256187-ofp7tupv	248	32	the	the	DT
cord-256187-ofp7tupv	248	33	second	second	JJ
cord-256187-ofp7tupv	248	34	filoviral	filoviral	JJ
cord-256187-ofp7tupv	248	35	genus	genus	NN
cord-256187-ofp7tupv	248	36	MARV	MARV	NNP
cord-256187-ofp7tupv	249	1	(	(	-LRB-
cord-256187-ofp7tupv	249	2	Kaletsky	Kaletsky	NNP
cord-256187-ofp7tupv	249	3	et	et	NNP
cord-256187-ofp7tupv	249	4	al	al	NNP
cord-256187-ofp7tupv	249	5	.	.	.
cord-256187-ofp7tupv	250	1	,	,	,
cord-256187-ofp7tupv	250	2	2009	2009	CD
cord-256187-ofp7tupv	250	3	;	;	:
cord-256187-ofp7tupv	250	4	Lopez	Lopez	NNP
cord-256187-ofp7tupv	250	5	et	et	NNP
cord-256187-ofp7tupv	250	6	al	al	NNP
cord-256187-ofp7tupv	250	7	.	.	NNP
cord-256187-ofp7tupv	250	8	,	,	,
cord-256187-ofp7tupv	250	9	2010	2010	CD
cord-256187-ofp7tupv	250	10	;	;	:
cord-256187-ofp7tupv	250	11	Radoshitzky	Radoshitzky	NNP
cord-256187-ofp7tupv	250	12	et	et	NNP
cord-256187-ofp7tupv	250	13	al	al	NNP
cord-256187-ofp7tupv	250	14	.	.	NNP
cord-256187-ofp7tupv	250	15	,	,	,
cord-256187-ofp7tupv	250	16	2010	2010	CD
cord-256187-ofp7tupv	251	1	;	;	:
cord-256187-ofp7tupv	251	2	Kühl	Kühl	NNP
cord-256187-ofp7tupv	251	3	et	et	NNP
cord-256187-ofp7tupv	251	4	al	al	NNP
cord-256187-ofp7tupv	251	5	.	.	NNP
cord-256187-ofp7tupv	251	6	,	,	,
cord-256187-ofp7tupv	251	7	2011a	2011a	CD
cord-256187-ofp7tupv	251	8	,	,	,
cord-256187-ofp7tupv	251	9	b	b	LS
cord-256187-ofp7tupv	251	10	)	)	-RRB-
cord-256187-ofp7tupv	251	11	.	.	.
cord-256187-ofp7tupv	252	1	The	the	DT
cord-256187-ofp7tupv	252	2	EBOV	EBOV	NNP
cord-256187-ofp7tupv	252	3	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	252	4	and	and	CC
cord-256187-ofp7tupv	252	5	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	252	6	Vpu	Vpu	NNP
cord-256187-ofp7tupv	252	7	employ	employ	VBP
cord-256187-ofp7tupv	252	8	different	different	JJ
cord-256187-ofp7tupv	252	9	strategies	strategy	NNS
cord-256187-ofp7tupv	252	10	to	to	TO
cord-256187-ofp7tupv	252	11	counteract	counteract	VB
cord-256187-ofp7tupv	252	12	tetherin	tetherin	NNS
cord-256187-ofp7tupv	253	1	The	the	DT
cord-256187-ofp7tupv	253	2	EBOV	EBOV	NNP
cord-256187-ofp7tupv	253	3	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	253	4	(	(	-LRB-
cord-256187-ofp7tupv	253	5	EBOV	EBOV	NNP
cord-256187-ofp7tupv	253	6	-	-	HYPH
cord-256187-ofp7tupv	253	7	GP	GP	NNP
cord-256187-ofp7tupv	253	8	1,2	1,2	CD
cord-256187-ofp7tupv	253	9	)	)	-RRB-
cord-256187-ofp7tupv	253	10	is	be	VBZ
cord-256187-ofp7tupv	253	11	the	the	DT
cord-256187-ofp7tupv	253	12	only	only	JJ
cord-256187-ofp7tupv	253	13	viral	viral	JJ
cord-256187-ofp7tupv	253	14	surface	surface	NN
cord-256187-ofp7tupv	253	15	protein	protein	NN
cord-256187-ofp7tupv	253	16	and	and	CC
cord-256187-ofp7tupv	253	17	mediates	mediate	VBZ
cord-256187-ofp7tupv	253	18	viral	viral	JJ
cord-256187-ofp7tupv	253	19	entry	entry	NN
cord-256187-ofp7tupv	253	20	into	into	IN
cord-256187-ofp7tupv	253	21	the	the	DT
cord-256187-ofp7tupv	253	22	host	host	NN
cord-256187-ofp7tupv	253	23	cell	cell	NN
cord-256187-ofp7tupv	253	24	that	that	WDT
cord-256187-ofp7tupv	253	25	requires	require	VBZ
cord-256187-ofp7tupv	253	26	binding	binding	NN
cord-256187-ofp7tupv	253	27	of	of	IN
cord-256187-ofp7tupv	253	28	GP	GP	NNP
cord-256187-ofp7tupv	253	29	1,2	1,2	CD
cord-256187-ofp7tupv	253	30	to	to	IN
cord-256187-ofp7tupv	253	31	the	the	DT
cord-256187-ofp7tupv	253	32	endosomal	endosomal	NNP
cord-256187-ofp7tupv	253	33	membrane	membrane	NN
cord-256187-ofp7tupv	253	34	protein	protein	NN
cord-256187-ofp7tupv	253	35	Niemann	Niemann	NNP
cord-256187-ofp7tupv	253	36	-	-	HYPH
cord-256187-ofp7tupv	253	37	Pick	Pick	NNP
cord-256187-ofp7tupv	253	38	C1	C1	NNP
cord-256187-ofp7tupv	253	39	(	(	-LRB-
cord-256187-ofp7tupv	253	40	NPC1	NPC1	NNP
cord-256187-ofp7tupv	253	41	)	)	-RRB-
cord-256187-ofp7tupv	254	1	(	(	-LRB-
cord-256187-ofp7tupv	254	2	Carette	Carette	NNP
cord-256187-ofp7tupv	254	3	et	et	NNP
cord-256187-ofp7tupv	254	4	al	al	NNP
cord-256187-ofp7tupv	254	5	.	.	NNP
cord-256187-ofp7tupv	254	6	,	,	,
cord-256187-ofp7tupv	254	7	2011	2011	CD
cord-256187-ofp7tupv	254	8	;	;	:
cord-256187-ofp7tupv	254	9	Cô	Cô	NNP
cord-256187-ofp7tupv	254	10	té	té	NNP
cord-256187-ofp7tupv	254	11	et	et	FW
cord-256187-ofp7tupv	254	12	al	al	NNP
cord-256187-ofp7tupv	254	13	.	.	.
cord-256187-ofp7tupv	255	1	,	,	,
cord-256187-ofp7tupv	255	2	2011	2011	CD
cord-256187-ofp7tupv	255	3	)	)	-RRB-
cord-256187-ofp7tupv	255	4	.	.	.
cord-256187-ofp7tupv	256	1	EBOV	EBOV	NNP
cord-256187-ofp7tupv	256	2	-	-	HYPH
cord-256187-ofp7tupv	256	3	GP	GP	NNP
cord-256187-ofp7tupv	256	4	1,2	1,2	CD
cord-256187-ofp7tupv	256	5	is	be	VBZ
cord-256187-ofp7tupv	256	6	synthesized	synthesize	VBN
cord-256187-ofp7tupv	256	7	as	as	IN
cord-256187-ofp7tupv	256	8	a	a	DT
cord-256187-ofp7tupv	256	9	precursor	precursor	NN
cord-256187-ofp7tupv	256	10	protein	protein	NN
cord-256187-ofp7tupv	256	11	,	,	,
cord-256187-ofp7tupv	256	12	which	which	WDT
cord-256187-ofp7tupv	256	13	is	be	VBZ
cord-256187-ofp7tupv	256	14	post	post	JJ
cord-256187-ofp7tupv	256	15	-	-	JJ
cord-256187-ofp7tupv	256	16	translationally	translationally	RB
cord-256187-ofp7tupv	256	17	cleaved	cleave	VBN
cord-256187-ofp7tupv	256	18	by	by	IN
cord-256187-ofp7tupv	256	19	subtilisin	subtilisin	NNS
cord-256187-ofp7tupv	256	20	-	-	HYPH
cord-256187-ofp7tupv	256	21	like	like	JJ
cord-256187-ofp7tupv	256	22	proteases	protease	NNS
cord-256187-ofp7tupv	256	23	into	into	IN
cord-256187-ofp7tupv	256	24	its	-PRON-	PRP$
cord-256187-ofp7tupv	256	25	two	two	CD
cord-256187-ofp7tupv	256	26	subunits	subunit	NNS
cord-256187-ofp7tupv	256	27	GP	GP	NNP
cord-256187-ofp7tupv	256	28	1	1	CD
cord-256187-ofp7tupv	256	29	and	and	CC
cord-256187-ofp7tupv	256	30	GP	GP	NNP
cord-256187-ofp7tupv	256	31	2	2	CD
cord-256187-ofp7tupv	257	1	(	(	-LRB-
cord-256187-ofp7tupv	257	2	Volchkov	Volchkov	NNP
cord-256187-ofp7tupv	257	3	et	et	NNP
cord-256187-ofp7tupv	257	4	al	al	NNP
cord-256187-ofp7tupv	257	5	.	.	NNP
cord-256187-ofp7tupv	257	6	,	,	,
cord-256187-ofp7tupv	257	7	1998	1998	CD
cord-256187-ofp7tupv	257	8	)	)	-RRB-
cord-256187-ofp7tupv	257	9	.	.	.
cord-256187-ofp7tupv	258	1	The	the	DT
cord-256187-ofp7tupv	258	2	large	large	JJ
cord-256187-ofp7tupv	258	3	and	and	CC
cord-256187-ofp7tupv	258	4	heavily	heavily	RB
cord-256187-ofp7tupv	258	5	glycosylated	glycosylate	VBN
cord-256187-ofp7tupv	258	6	,	,	,
cord-256187-ofp7tupv	258	7	extracellular	extracellular	JJ
cord-256187-ofp7tupv	258	8	domain	domain	NN
cord-256187-ofp7tupv	258	9	GP	GP	NNP
cord-256187-ofp7tupv	258	10	1	1	CD
cord-256187-ofp7tupv	258	11	mediates	mediate	VBZ
cord-256187-ofp7tupv	258	12	attachment	attachment	NN
cord-256187-ofp7tupv	258	13	to	to	IN
cord-256187-ofp7tupv	258	14	the	the	DT
cord-256187-ofp7tupv	258	15	host	host	NN
cord-256187-ofp7tupv	258	16	cell	cell	NN
cord-256187-ofp7tupv	258	17	;	;	:
cord-256187-ofp7tupv	258	18	the	the	DT
cord-256187-ofp7tupv	258	19	smaller	small	JJR
cord-256187-ofp7tupv	258	20	TM	TM	NNP
cord-256187-ofp7tupv	258	21	unit	unit	NN
cord-256187-ofp7tupv	258	22	GP	GP	NNP
cord-256187-ofp7tupv	258	23	2	2	CD
cord-256187-ofp7tupv	258	24	facilitates	facilitate	VBZ
cord-256187-ofp7tupv	258	25	fusion	fusion	NN
cord-256187-ofp7tupv	258	26	of	of	IN
cord-256187-ofp7tupv	258	27	the	the	DT
cord-256187-ofp7tupv	258	28	viral	viral	JJ
cord-256187-ofp7tupv	258	29	envelope	envelope	NN
cord-256187-ofp7tupv	258	30	with	with	IN
cord-256187-ofp7tupv	258	31	the	the	DT
cord-256187-ofp7tupv	258	32	membrane	membrane	NN
cord-256187-ofp7tupv	258	33	of	of	IN
cord-256187-ofp7tupv	258	34	host	host	NN
cord-256187-ofp7tupv	258	35	cell	cell	NN
cord-256187-ofp7tupv	258	36	endosomes	endosome	NNS
cord-256187-ofp7tupv	258	37	(	(	-LRB-
cord-256187-ofp7tupv	258	38	Takada	Takada	NNP
cord-256187-ofp7tupv	258	39	et	et	FW
cord-256187-ofp7tupv	258	40	al	al	NNP
cord-256187-ofp7tupv	258	41	.	.	NNP
cord-256187-ofp7tupv	258	42	,	,	,
cord-256187-ofp7tupv	258	43	1997	1997	CD
cord-256187-ofp7tupv	258	44	;	;	:
cord-256187-ofp7tupv	258	45	Wool	Wool	NNP
cord-256187-ofp7tupv	258	46	-	-	HYPH
cord-256187-ofp7tupv	258	47	Lewis	Lewis	NNP
cord-256187-ofp7tupv	258	48	and	and	CC
cord-256187-ofp7tupv	258	49	Bates	Bates	NNP
cord-256187-ofp7tupv	258	50	,	,	,
cord-256187-ofp7tupv	258	51	1998	1998	CD
cord-256187-ofp7tupv	258	52	)	)	-RRB-
cord-256187-ofp7tupv	258	53	.	.	.
cord-256187-ofp7tupv	259	1	A	a	DT
cord-256187-ofp7tupv	259	2	recent	recent	JJ
cord-256187-ofp7tupv	259	3	study	study	NN
cord-256187-ofp7tupv	259	4	demonstrated	demonstrate	VBD
cord-256187-ofp7tupv	259	5	that	that	IN
cord-256187-ofp7tupv	259	6	GP	GP	NNP
cord-256187-ofp7tupv	259	7	1,2	1,2	CD
cord-256187-ofp7tupv	259	8	also	also	RB
cord-256187-ofp7tupv	259	9	inactivates	inactivate	VBZ
cord-256187-ofp7tupv	259	10	one	one	CD
cord-256187-ofp7tupv	259	11	of	of	IN
cord-256187-ofp7tupv	259	12	the	the	DT
cord-256187-ofp7tupv	259	13	cell	cell	NN
cord-256187-ofp7tupv	259	14	's	's	POS
cord-256187-ofp7tupv	259	15	innate	innate	JJ
cord-256187-ofp7tupv	259	16	defences	defence	NNS
cord-256187-ofp7tupv	259	17	against	against	IN
cord-256187-ofp7tupv	259	18	infection	infection	NN
cord-256187-ofp7tupv	259	19	,	,	,
cord-256187-ofp7tupv	259	20	the	the	DT
cord-256187-ofp7tupv	259	21	tetherin	tetherin	NN
cord-256187-ofp7tupv	259	22	protein	protein	NN
cord-256187-ofp7tupv	259	23	(	(	-LRB-
cord-256187-ofp7tupv	259	24	Kaletsky	Kaletsky	NNP
cord-256187-ofp7tupv	259	25	et	et	NNP
cord-256187-ofp7tupv	259	26	al	al	NNP
cord-256187-ofp7tupv	259	27	.	.	NNP
cord-256187-ofp7tupv	259	28	,	,	,
cord-256187-ofp7tupv	259	29	2009	2009	CD
cord-256187-ofp7tupv	259	30	)	)	-RRB-
cord-256187-ofp7tupv	259	31	.	.	.
cord-256187-ofp7tupv	260	1	Vpu	Vpu	NNP
cord-256187-ofp7tupv	260	2	allows	allow	VBZ
cord-256187-ofp7tupv	260	3	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	260	4	to	to	TO
cord-256187-ofp7tupv	260	5	evade	evade	VB
cord-256187-ofp7tupv	260	6	tetherin	tetherin	NNS
cord-256187-ofp7tupv	260	7	by	by	IN
cord-256187-ofp7tupv	260	8	mediating	mediate	VBG
cord-256187-ofp7tupv	260	9	cell	cell	NN
cord-256187-ofp7tupv	260	10	surface	surface	NN
cord-256187-ofp7tupv	260	11	downregulation	downregulation	NN
cord-256187-ofp7tupv	260	12	and	and	CC
cord-256187-ofp7tupv	260	13	relocalization	relocalization	NN
cord-256187-ofp7tupv	260	14	of	of	IN
cord-256187-ofp7tupv	260	15	tetherin	tetherin	NNP
cord-256187-ofp7tupv	260	16	into	into	IN
cord-256187-ofp7tupv	260	17	intracellular	intracellular	JJ
cord-256187-ofp7tupv	260	18	compartments	compartment	NNS
cord-256187-ofp7tupv	260	19	(	(	-LRB-
cord-256187-ofp7tupv	260	20	Van	Van	NNP
cord-256187-ofp7tupv	260	21	Damme	Damme	NNP
cord-256187-ofp7tupv	260	22	et	et	FW
cord-256187-ofp7tupv	260	23	al	al	NNP
cord-256187-ofp7tupv	260	24	.	.	NNP
cord-256187-ofp7tupv	260	25	,	,	,
cord-256187-ofp7tupv	260	26	2008	2008	CD
cord-256187-ofp7tupv	260	27	)	)	-RRB-
cord-256187-ofp7tupv	260	28	.	.	.
cord-256187-ofp7tupv	261	1	In	in	IN
cord-256187-ofp7tupv	261	2	addition	addition	NN
cord-256187-ofp7tupv	261	3	,	,	,
cord-256187-ofp7tupv	261	4	Vpu	Vpu	NNP
cord-256187-ofp7tupv	261	5	facilitates	facilitate	VBZ
cord-256187-ofp7tupv	261	6	degradation	degradation	NN
cord-256187-ofp7tupv	261	7	of	of	IN
cord-256187-ofp7tupv	261	8	tetherin	tetherin	NN
cord-256187-ofp7tupv	261	9	in	in	IN
cord-256187-ofp7tupv	261	10	lysosomal	lysosomal	JJ
cord-256187-ofp7tupv	261	11	or	or	CC
cord-256187-ofp7tupv	261	12	proteasomal	proteasomal	JJ
cord-256187-ofp7tupv	261	13	compartments	compartment	NNS
cord-256187-ofp7tupv	261	14	Goffinet	Goffinet	NNP
cord-256187-ofp7tupv	261	15	et	et	FW
cord-256187-ofp7tupv	261	16	al	al	NNP
cord-256187-ofp7tupv	261	17	.	.	NNP
cord-256187-ofp7tupv	261	18	,	,	,
cord-256187-ofp7tupv	261	19	2009	2009	CD
cord-256187-ofp7tupv	262	1	Goffinet	Goffinet	NNP
cord-256187-ofp7tupv	262	2	et	et	FW
cord-256187-ofp7tupv	262	3	al	al	NNP
cord-256187-ofp7tupv	262	4	.	.	.
cord-256187-ofp7tupv	263	1	,	,	,
cord-256187-ofp7tupv	263	2	,	,	,
cord-256187-ofp7tupv	263	3	2010	2010	CD
cord-256187-ofp7tupv	263	4	Mangeat	Mangeat	NNP
cord-256187-ofp7tupv	263	5	et	et	NNP
cord-256187-ofp7tupv	263	6	al	al	NNP
cord-256187-ofp7tupv	263	7	.	.	.
cord-256187-ofp7tupv	264	1	,	,	,
cord-256187-ofp7tupv	264	2	2009	2009	CD
cord-256187-ofp7tupv	264	3	;	;	:
cord-256187-ofp7tupv	264	4	Mitchell	Mitchell	NNP
cord-256187-ofp7tupv	264	5	et	et	NNP
cord-256187-ofp7tupv	264	6	al	al	NNP
cord-256187-ofp7tupv	264	7	.	.	NNP
cord-256187-ofp7tupv	264	8	,	,	,
cord-256187-ofp7tupv	264	9	2009	2009	CD
cord-256187-ofp7tupv	264	10	;	;	:
cord-256187-ofp7tupv	264	11	Dubé	Dubé	NNP
cord-256187-ofp7tupv	264	12	et	et	FW
cord-256187-ofp7tupv	264	13	al	al	NNP
cord-256187-ofp7tupv	264	14	.	.	NNP
cord-256187-ofp7tupv	264	15	,	,	,
cord-256187-ofp7tupv	264	16	2010	2010	CD
cord-256187-ofp7tupv	264	17	)	)	-RRB-
cord-256187-ofp7tupv	264	18	.	.	.
cord-256187-ofp7tupv	265	1	In	in	IN
cord-256187-ofp7tupv	265	2	contrast	contrast	NN
cord-256187-ofp7tupv	265	3	,	,	,
cord-256187-ofp7tupv	265	4	no	no	DT
cord-256187-ofp7tupv	265	5	evidence	evidence	NN
cord-256187-ofp7tupv	265	6	for	for	IN
cord-256187-ofp7tupv	265	7	downregulation	downregulation	NN
cord-256187-ofp7tupv	265	8	,	,	,
cord-256187-ofp7tupv	265	9	relocalization	relocalization	NN
cord-256187-ofp7tupv	265	10	away	away	RB
cord-256187-ofp7tupv	265	11	from	from	IN
cord-256187-ofp7tupv	265	12	the	the	DT
cord-256187-ofp7tupv	265	13	cell	cell	NN
cord-256187-ofp7tupv	265	14	surface	surface	NN
cord-256187-ofp7tupv	265	15	or	or	CC
cord-256187-ofp7tupv	265	16	degradation	degradation	NN
cord-256187-ofp7tupv	265	17	of	of	IN
cord-256187-ofp7tupv	265	18	tetherin	tetherin	NNP
cord-256187-ofp7tupv	265	19	was	be	VBD
cord-256187-ofp7tupv	265	20	observed	observe	VBN
cord-256187-ofp7tupv	265	21	in	in	IN
cord-256187-ofp7tupv	265	22	the	the	DT
cord-256187-ofp7tupv	265	23	presence	presence	NN
cord-256187-ofp7tupv	265	24	of	of	IN
cord-256187-ofp7tupv	265	25	EBOV	EBOV	NNP
cord-256187-ofp7tupv	265	26	-	-	HYPH
cord-256187-ofp7tupv	265	27	GP	GP	NNP
cord-256187-ofp7tupv	265	28	1,2	1,2	CD
cord-256187-ofp7tupv	265	29	or	or	CC
cord-256187-ofp7tupv	265	30	MARV	MARV	NNP
cord-256187-ofp7tupv	265	31	-	-	HYPH
cord-256187-ofp7tupv	265	32	GP	GP	NNP
cord-256187-ofp7tupv	265	33	1,2	1,2	CD
cord-256187-ofp7tupv	266	1	(	(	-LRB-
cord-256187-ofp7tupv	266	2	Kaletsky	Kaletsky	NNP
cord-256187-ofp7tupv	266	3	et	et	NNP
cord-256187-ofp7tupv	266	4	al	al	NNP
cord-256187-ofp7tupv	266	5	.	.	.
cord-256187-ofp7tupv	267	1	,	,	,
cord-256187-ofp7tupv	267	2	2009	2009	CD
cord-256187-ofp7tupv	267	3	;	;	:
cord-256187-ofp7tupv	267	4	Lopez	Lopez	NNP
cord-256187-ofp7tupv	267	5	et	et	NNP
cord-256187-ofp7tupv	267	6	al	al	NNP
cord-256187-ofp7tupv	267	7	.	.	NNP
cord-256187-ofp7tupv	267	8	,	,	,
cord-256187-ofp7tupv	267	9	2010	2010	CD
cord-256187-ofp7tupv	267	10	;	;	:
cord-256187-ofp7tupv	267	11	Radoshitzky	Radoshitzky	NNP
cord-256187-ofp7tupv	267	12	et	et	NNP
cord-256187-ofp7tupv	267	13	al	al	NNP
cord-256187-ofp7tupv	267	14	.	.	NNP
cord-256187-ofp7tupv	267	15	,	,	,
cord-256187-ofp7tupv	267	16	2010	2010	CD
cord-256187-ofp7tupv	268	1	;	;	:
cord-256187-ofp7tupv	268	2	Kühl	Kühl	NNP
cord-256187-ofp7tupv	268	3	et	et	FW
cord-256187-ofp7tupv	268	4	al	al	NNP
cord-256187-ofp7tupv	268	5	.	.	.
cord-256187-ofp7tupv	269	1	,	,	,
cord-256187-ofp7tupv	269	2	2011a	2011a	CD
cord-256187-ofp7tupv	269	3	)	)	-RRB-
cord-256187-ofp7tupv	269	4	.	.	.
cord-256187-ofp7tupv	270	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	270	2	,	,	,
cord-256187-ofp7tupv	270	3	EBOV	EBOV	NNP
cord-256187-ofp7tupv	270	4	-	-	HYPH
cord-256187-ofp7tupv	270	5	GP	GP	NNP
cord-256187-ofp7tupv	270	6	1,2	1,2	CD
cord-256187-ofp7tupv	270	7	is	be	VBZ
cord-256187-ofp7tupv	270	8	active	active	JJ
cord-256187-ofp7tupv	270	9	against	against	IN
cord-256187-ofp7tupv	270	10	tetherin	tetherin	NNP
cord-256187-ofp7tupv	270	11	homologues	homologue	NNS
cord-256187-ofp7tupv	270	12	from	from	IN
cord-256187-ofp7tupv	270	13	different	different	JJ
cord-256187-ofp7tupv	270	14	monkeys	monkey	NNS
cord-256187-ofp7tupv	270	15	,	,	,
cord-256187-ofp7tupv	270	16	in	in	IN
cord-256187-ofp7tupv	270	17	accordance	accordance	NN
cord-256187-ofp7tupv	270	18	with	with	IN
cord-256187-ofp7tupv	270	19	the	the	DT
cord-256187-ofp7tupv	270	20	ability	ability	NN
cord-256187-ofp7tupv	270	21	of	of	IN
cord-256187-ofp7tupv	270	22	EBOV	EBOV	NNP
cord-256187-ofp7tupv	270	23	to	to	TO
cord-256187-ofp7tupv	270	24	infect	infect	VB
cord-256187-ofp7tupv	270	25	several	several	JJ
cord-256187-ofp7tupv	270	26	non	non	JJ
cord-256187-ofp7tupv	270	27	-	-	JJ
cord-256187-ofp7tupv	270	28	human	human	JJ
cord-256187-ofp7tupv	270	29	primates	primate	NNS
cord-256187-ofp7tupv	271	1	(	(	-LRB-
cord-256187-ofp7tupv	271	2	Kühl	Kühl	NNP
cord-256187-ofp7tupv	271	3	et	et	FW
cord-256187-ofp7tupv	271	4	al	al	NNP
cord-256187-ofp7tupv	271	5	.	.	NNP
cord-256187-ofp7tupv	271	6	,	,	,
cord-256187-ofp7tupv	271	7	2011a	2011a	CD
cord-256187-ofp7tupv	271	8	)	)	-RRB-
cord-256187-ofp7tupv	271	9	.	.	.
cord-256187-ofp7tupv	272	1	In	in	IN
cord-256187-ofp7tupv	272	2	contrast	contrast	NN
cord-256187-ofp7tupv	272	3	,	,	,
cord-256187-ofp7tupv	272	4	tetherin	tetherin	NN
cord-256187-ofp7tupv	272	5	antagonism	antagonism	NN
cord-256187-ofp7tupv	272	6	by	by	IN
cord-256187-ofp7tupv	272	7	Vpu	Vpu	NNP
cord-256187-ofp7tupv	272	8	is	be	VBZ
cord-256187-ofp7tupv	272	9	limited	limit	VBN
cord-256187-ofp7tupv	272	10	to	to	IN
cord-256187-ofp7tupv	272	11	tetherin	tetherin	NNP
cord-256187-ofp7tupv	272	12	of	of	IN
cord-256187-ofp7tupv	272	13	human	human	NN
cord-256187-ofp7tupv	272	14	,	,	,
cord-256187-ofp7tupv	272	15	chimpanzee	chimpanzee	NN
cord-256187-ofp7tupv	272	16	and	and	CC
cord-256187-ofp7tupv	272	17	gorilla	gorilla	NN
cord-256187-ofp7tupv	272	18	origin	origin	NN
cord-256187-ofp7tupv	272	19	,	,	,
cord-256187-ofp7tupv	272	20	and	and	CC
cord-256187-ofp7tupv	272	21	these	these	DT
cord-256187-ofp7tupv	272	22	species	specie	NNS
cord-256187-ofp7tupv	272	23	are	be	VBP
cord-256187-ofp7tupv	272	24	infected	infect	VBN
cord-256187-ofp7tupv	272	25	by	by	IN
cord-256187-ofp7tupv	272	26	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	272	27	and	and	CC
cord-256187-ofp7tupv	272	28	Vpu	Vpu	NNP
cord-256187-ofp7tupv	272	29	encoding	encoding	NN
cord-256187-ofp7tupv	272	30	SIV	SIV	NNP
cord-256187-ofp7tupv	272	31	,	,	,
cord-256187-ofp7tupv	272	32	respectively	respectively	RB
cord-256187-ofp7tupv	272	33	(	(	-LRB-
cord-256187-ofp7tupv	272	34	Goffinet	Goffinet	NNP
cord-256187-ofp7tupv	272	35	et	et	FW
cord-256187-ofp7tupv	272	36	al	al	NNP
cord-256187-ofp7tupv	272	37	.	.	NNP
cord-256187-ofp7tupv	272	38	,	,	,
cord-256187-ofp7tupv	272	39	2009	2009	CD
cord-256187-ofp7tupv	272	40	;	;	:
cord-256187-ofp7tupv	272	41	Jia	Jia	NNP
cord-256187-ofp7tupv	272	42	et	et	NNP
cord-256187-ofp7tupv	272	43	al	al	NNP
cord-256187-ofp7tupv	272	44	.	.	NNP
cord-256187-ofp7tupv	272	45	,	,	,
cord-256187-ofp7tupv	272	46	2009	2009	CD
cord-256187-ofp7tupv	272	47	;	;	:
cord-256187-ofp7tupv	272	48	McNatt	McNatt	NNP
cord-256187-ofp7tupv	272	49	et	et	NNP
cord-256187-ofp7tupv	272	50	al	al	NNP
cord-256187-ofp7tupv	272	51	.	.	NNP
cord-256187-ofp7tupv	272	52	,	,	,
cord-256187-ofp7tupv	272	53	2009	2009	CD
cord-256187-ofp7tupv	272	54	)	)	-RRB-
cord-256187-ofp7tupv	272	55	.	.	.
cord-256187-ofp7tupv	273	1	Thus	thus	RB
cord-256187-ofp7tupv	273	2	,	,	,
cord-256187-ofp7tupv	273	3	Vpu	Vpu	NNP
cord-256187-ofp7tupv	273	4	and	and	CC
cord-256187-ofp7tupv	273	5	EBOV	EBOV	NNP
cord-256187-ofp7tupv	273	6	-	-	HYPH
cord-256187-ofp7tupv	273	7	GP	GP	NNP
cord-256187-ofp7tupv	273	8	1,2	1,2	CD
cord-256187-ofp7tupv	273	9	have	have	VBP
cord-256187-ofp7tupv	273	10	a	a	DT
cord-256187-ofp7tupv	273	11	different	different	JJ
cord-256187-ofp7tupv	273	12	specificity	specificity	NN
cord-256187-ofp7tupv	273	13	for	for	IN
cord-256187-ofp7tupv	273	14	tetherin	tetherin	NNP
cord-256187-ofp7tupv	273	15	and	and	CC
cord-256187-ofp7tupv	273	16	employ	employ	VB
cord-256187-ofp7tupv	273	17	different	different	JJ
cord-256187-ofp7tupv	273	18	strategies	strategy	NNS
cord-256187-ofp7tupv	273	19	to	to	TO
cord-256187-ofp7tupv	273	20	counteract	counteract	VB
cord-256187-ofp7tupv	273	21	tetherin	tetherin	NNS
cord-256187-ofp7tupv	273	22	.	.	.
cord-256187-ofp7tupv	274	1	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	274	2	interacts	interact	VBZ
cord-256187-ofp7tupv	274	3	with	with	IN
cord-256187-ofp7tupv	274	4	the	the	DT
cord-256187-ofp7tupv	274	5	GP	GP	NNP
cord-256187-ofp7tupv	274	6	2	2	CD
cord-256187-ofp7tupv	274	7	subunit	subunit	NN
cord-256187-ofp7tupv	274	8	of	of	IN
cord-256187-ofp7tupv	274	9	the	the	DT
cord-256187-ofp7tupv	274	10	EBOV	EBOV	NNP
cord-256187-ofp7tupv	274	11	-	-	HYPH
cord-256187-ofp7tupv	274	12	GP	GP	NNP
cord-256187-ofp7tupv	274	13	1,2	1,2	CD
cord-256187-ofp7tupv	275	1	Four	four	CD
cord-256187-ofp7tupv	275	2	different	different	JJ
cord-256187-ofp7tupv	275	3	proteins	protein	NNS
cord-256187-ofp7tupv	275	4	are	be	VBP
cord-256187-ofp7tupv	275	5	expressed	express	VBN
cord-256187-ofp7tupv	275	6	from	from	IN
cord-256187-ofp7tupv	275	7	the	the	DT
cord-256187-ofp7tupv	275	8	EBOV	EBOV	NNP
cord-256187-ofp7tupv	275	9	-	-	HYPH
cord-256187-ofp7tupv	275	10	GP	gp	NN
cord-256187-ofp7tupv	275	11	gene	gene	NN
cord-256187-ofp7tupv	275	12	:	:	:
cord-256187-ofp7tupv	275	13	(	(	-LRB-
cord-256187-ofp7tupv	275	14	i	i	NN
cord-256187-ofp7tupv	275	15	)	)	-RRB-
cord-256187-ofp7tupv	276	1	The	the	DT
cord-256187-ofp7tupv	276	2	primary	primary	JJ
cord-256187-ofp7tupv	276	3	transcript	transcript	NN
cord-256187-ofp7tupv	276	4	from	from	IN
cord-256187-ofp7tupv	276	5	the	the	DT
cord-256187-ofp7tupv	276	6	GP	GP	NNP
cord-256187-ofp7tupv	276	7	gene	gene	NN
cord-256187-ofp7tupv	276	8	is	be	VBZ
cord-256187-ofp7tupv	276	9	sGP	sgp	XX
cord-256187-ofp7tupv	276	10	,	,	,
cord-256187-ofp7tupv	276	11	a	a	DT
cord-256187-ofp7tupv	276	12	soluble	soluble	JJ
cord-256187-ofp7tupv	276	13	,	,	,
cord-256187-ofp7tupv	276	14	secreted	secrete	VBN
cord-256187-ofp7tupv	276	15	form	form	NN
cord-256187-ofp7tupv	276	16	of	of	IN
cord-256187-ofp7tupv	276	17	the	the	DT
cord-256187-ofp7tupv	276	18	GP	GP	NNP
cord-256187-ofp7tupv	276	19	(	(	-LRB-
cord-256187-ofp7tupv	276	20	Volchkov	Volchkov	NNP
cord-256187-ofp7tupv	276	21	et	et	NNP
cord-256187-ofp7tupv	276	22	al	al	NNP
cord-256187-ofp7tupv	276	23	.	.	NNP
cord-256187-ofp7tupv	276	24	,	,	,
cord-256187-ofp7tupv	276	25	1995	1995	CD
cord-256187-ofp7tupv	276	26	;	;	:
cord-256187-ofp7tupv	276	27	Sanchez	Sanchez	NNP
cord-256187-ofp7tupv	276	28	et	et	NNP
cord-256187-ofp7tupv	276	29	al	al	NNP
cord-256187-ofp7tupv	276	30	.	.	NNP
cord-256187-ofp7tupv	276	31	,	,	,
cord-256187-ofp7tupv	276	32	1996	1996	CD
cord-256187-ofp7tupv	276	33	)	)	-RRB-
cord-256187-ofp7tupv	276	34	,	,	,
cord-256187-ofp7tupv	276	35	which	which	WDT
cord-256187-ofp7tupv	276	36	has	have	VBZ
cord-256187-ofp7tupv	276	37	an	an	DT
cord-256187-ofp7tupv	276	38	anti	anti	JJ
cord-256187-ofp7tupv	276	39	-	-	JJ
cord-256187-ofp7tupv	276	40	inflammatory	inflammatory	JJ
cord-256187-ofp7tupv	276	41	property	property	NN
cord-256187-ofp7tupv	276	42	(	(	-LRB-
cord-256187-ofp7tupv	276	43	Wahl	Wahl	NNP
cord-256187-ofp7tupv	276	44	-	-	HYPH
cord-256187-ofp7tupv	276	45	Jensen	Jensen	NNP
cord-256187-ofp7tupv	276	46	et	et	NNP
cord-256187-ofp7tupv	276	47	al	al	NNP
cord-256187-ofp7tupv	276	48	.	.	NNP
cord-256187-ofp7tupv	276	49	,	,	,
cord-256187-ofp7tupv	276	50	2005	2005	CD
cord-256187-ofp7tupv	276	51	)	)	-RRB-
cord-256187-ofp7tupv	276	52	.	.	.
cord-256187-ofp7tupv	277	1	(	(	-LRB-
cord-256187-ofp7tupv	277	2	ii	ii	NN
cord-256187-ofp7tupv	277	3	)	)	-RRB-
cord-256187-ofp7tupv	278	1	A	a	DT
cord-256187-ofp7tupv	278	2	soluble	soluble	JJ
cord-256187-ofp7tupv	278	3	D	d	NN
cord-256187-ofp7tupv	278	4	-	-	HYPH
cord-256187-ofp7tupv	278	5	peptide	peptide	NN
cord-256187-ofp7tupv	278	6	is	be	VBZ
cord-256187-ofp7tupv	278	7	released	release	VBN
cord-256187-ofp7tupv	278	8	upon	upon	IN
cord-256187-ofp7tupv	278	9	proteolytic	proteolytic	JJ
cord-256187-ofp7tupv	278	10	processing	processing	NN
cord-256187-ofp7tupv	278	11	of	of	IN
cord-256187-ofp7tupv	278	12	sGP	sgp	NN
cord-256187-ofp7tupv	278	13	by	by	IN
cord-256187-ofp7tupv	278	14	furin	furin	NN
cord-256187-ofp7tupv	278	15	(	(	-LRB-
cord-256187-ofp7tupv	278	16	Volchkova	Volchkova	NNP
cord-256187-ofp7tupv	278	17	et	et	NNP
cord-256187-ofp7tupv	278	18	al	al	NNP
cord-256187-ofp7tupv	278	19	.	.	NNP
cord-256187-ofp7tupv	278	20	,	,	,
cord-256187-ofp7tupv	278	21	1999	1999	CD
cord-256187-ofp7tupv	278	22	)	)	-RRB-
cord-256187-ofp7tupv	278	23	.	.	.
cord-256187-ofp7tupv	279	1	(	(	-LRB-
cord-256187-ofp7tupv	279	2	iii	iii	NN
cord-256187-ofp7tupv	279	3	)	)	-RRB-
cord-256187-ofp7tupv	280	1	The	the	DT
cord-256187-ofp7tupv	280	2	full	full	JJ
cord-256187-ofp7tupv	280	3	-	-	HYPH
cord-256187-ofp7tupv	280	4	length	length	NN
cord-256187-ofp7tupv	280	5	,	,	,
cord-256187-ofp7tupv	280	6	membrane	membrane	NN
cord-256187-ofp7tupv	280	7	-	-	HYPH
cord-256187-ofp7tupv	280	8	bound	bind	VBN
cord-256187-ofp7tupv	280	9	form	form	NN
cord-256187-ofp7tupv	280	10	GP	GP	NNP
cord-256187-ofp7tupv	280	11	1,2	1,2	CD
cord-256187-ofp7tupv	280	12	,	,	,
cord-256187-ofp7tupv	280	13	which	which	WDT
cord-256187-ofp7tupv	280	14	is	be	VBZ
cord-256187-ofp7tupv	280	15	incorporated	incorporate	VBN
cord-256187-ofp7tupv	280	16	into	into	IN
cord-256187-ofp7tupv	280	17	the	the	DT
cord-256187-ofp7tupv	280	18	virions	virion	NNS
cord-256187-ofp7tupv	280	19	,	,	,
cord-256187-ofp7tupv	280	20	is	be	VBZ
cord-256187-ofp7tupv	280	21	produced	produce	VBN
cord-256187-ofp7tupv	280	22	by	by	IN
cord-256187-ofp7tupv	280	23	RNA	RNA	NNP
cord-256187-ofp7tupv	280	24	editing	editing	NN
cord-256187-ofp7tupv	280	25	of	of	IN
cord-256187-ofp7tupv	280	26	the	the	DT
cord-256187-ofp7tupv	280	27	primary	primary	JJ
cord-256187-ofp7tupv	280	28	transcript	transcript	NN
cord-256187-ofp7tupv	280	29	(	(	-LRB-
cord-256187-ofp7tupv	280	30	Volchkov	Volchkov	NNP
cord-256187-ofp7tupv	280	31	et	et	NNP
cord-256187-ofp7tupv	280	32	al	al	NNP
cord-256187-ofp7tupv	280	33	.	.	NNP
cord-256187-ofp7tupv	280	34	,	,	,
cord-256187-ofp7tupv	280	35	1995	1995	CD
cord-256187-ofp7tupv	280	36	;	;	:
cord-256187-ofp7tupv	280	37	Sanchez	Sanchez	NNP
cord-256187-ofp7tupv	280	38	et	et	NNP
cord-256187-ofp7tupv	280	39	al	al	NNP
cord-256187-ofp7tupv	280	40	.	.	NNP
cord-256187-ofp7tupv	280	41	,	,	,
cord-256187-ofp7tupv	280	42	1996	1996	CD
cord-256187-ofp7tupv	280	43	)	)	-RRB-
cord-256187-ofp7tupv	280	44	.	.	.
cord-256187-ofp7tupv	281	1	(	(	-LRB-
cord-256187-ofp7tupv	281	2	iv	iv	LS
cord-256187-ofp7tupv	281	3	)	)	-RRB-
cord-256187-ofp7tupv	282	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	282	2	,	,	,
cord-256187-ofp7tupv	282	3	a	a	DT
cord-256187-ofp7tupv	282	4	small	small	JJ
cord-256187-ofp7tupv	282	5	soluble	soluble	JJ
cord-256187-ofp7tupv	282	6	GP	gp	NN
cord-256187-ofp7tupv	282	7	(	(	-LRB-
cord-256187-ofp7tupv	282	8	ssGP	ssGP	NNP
cord-256187-ofp7tupv	282	9	)	)	-RRB-
cord-256187-ofp7tupv	282	10	has	have	VBZ
cord-256187-ofp7tupv	282	11	recently	recently	RB
cord-256187-ofp7tupv	282	12	been	be	VBN
cord-256187-ofp7tupv	282	13	identified	identify	VBN
cord-256187-ofp7tupv	282	14	,	,	,
cord-256187-ofp7tupv	282	15	but	but	CC
cord-256187-ofp7tupv	282	16	the	the	DT
cord-256187-ofp7tupv	282	17	function	function	NN
cord-256187-ofp7tupv	282	18	of	of	IN
cord-256187-ofp7tupv	282	19	this	this	DT
cord-256187-ofp7tupv	282	20	protein	protein	NN
cord-256187-ofp7tupv	282	21	is	be	VBZ
cord-256187-ofp7tupv	282	22	at	at	IN
cord-256187-ofp7tupv	282	23	present	present	JJ
cord-256187-ofp7tupv	282	24	unknown	unknown	NN
cord-256187-ofp7tupv	283	1	(	(	-LRB-
cord-256187-ofp7tupv	283	2	Mehedi	Mehedi	NNP
cord-256187-ofp7tupv	283	3	et	et	NNP
cord-256187-ofp7tupv	283	4	al	al	NNP
cord-256187-ofp7tupv	283	5	.	.	NNP
cord-256187-ofp7tupv	283	6	,	,	,
cord-256187-ofp7tupv	283	7	2011	2011	CD
cord-256187-ofp7tupv	283	8	)	)	-RRB-
cord-256187-ofp7tupv	283	9	.	.	.
cord-256187-ofp7tupv	284	1	In	in	IN
cord-256187-ofp7tupv	284	2	addition	addition	NN
cord-256187-ofp7tupv	284	3	,	,	,
cord-256187-ofp7tupv	284	4	the	the	DT
cord-256187-ofp7tupv	284	5	TNFa	TNFa	NNS
cord-256187-ofp7tupv	284	6	converting	convert	VBG
cord-256187-ofp7tupv	284	7	enzyme	enzyme	NN
cord-256187-ofp7tupv	284	8	induces	induce	VBZ
cord-256187-ofp7tupv	284	9	shedding	shed	VBG
cord-256187-ofp7tupv	284	10	of	of	IN
cord-256187-ofp7tupv	284	11	GP	GP	NNP
cord-256187-ofp7tupv	284	12	1,2D	1,2d	CD
cord-256187-ofp7tupv	284	13	from	from	IN
cord-256187-ofp7tupv	284	14	the	the	DT
cord-256187-ofp7tupv	284	15	surface	surface	NN
cord-256187-ofp7tupv	284	16	of	of	IN
cord-256187-ofp7tupv	284	17	infected	infected	JJ
cord-256187-ofp7tupv	284	18	cells	cell	NNS
cord-256187-ofp7tupv	284	19	by	by	IN
cord-256187-ofp7tupv	284	20	cleaving	cleave	VBG
cord-256187-ofp7tupv	284	21	GP	GP	NNP
cord-256187-ofp7tupv	284	22	1,2	1,2	CD
cord-256187-ofp7tupv	284	23	near	near	IN
cord-256187-ofp7tupv	284	24	the	the	DT
cord-256187-ofp7tupv	284	25	TM	TM	NNP
cord-256187-ofp7tupv	284	26	domain	domain	NN
cord-256187-ofp7tupv	284	27	(	(	-LRB-
cord-256187-ofp7tupv	284	28	Dolnik	Dolnik	NNP
cord-256187-ofp7tupv	284	29	et	et	FW
cord-256187-ofp7tupv	284	30	al	al	NNP
cord-256187-ofp7tupv	284	31	.	.	NNP
cord-256187-ofp7tupv	284	32	,	,	,
cord-256187-ofp7tupv	284	33	2004	2004	CD
cord-256187-ofp7tupv	284	34	)	)	-RRB-
cord-256187-ofp7tupv	284	35	.	.	.
cord-256187-ofp7tupv	285	1	All	all	DT
cord-256187-ofp7tupv	285	2	different	different	JJ
cord-256187-ofp7tupv	285	3	forms	form	NNS
cord-256187-ofp7tupv	285	4	of	of	IN
cord-256187-ofp7tupv	285	5	the	the	DT
cord-256187-ofp7tupv	285	6	GP	gp	NN
cord-256187-ofp7tupv	285	7	might	may	MD
cord-256187-ofp7tupv	285	8	play	play	VB
cord-256187-ofp7tupv	285	9	a	a	DT
cord-256187-ofp7tupv	285	10	role	role	NN
cord-256187-ofp7tupv	285	11	in	in	IN
cord-256187-ofp7tupv	285	12	combating	combat	VBG
cord-256187-ofp7tupv	285	13	the	the	DT
cord-256187-ofp7tupv	285	14	host	host	NN
cord-256187-ofp7tupv	285	15	's	's	POS
cord-256187-ofp7tupv	285	16	immune	immune	JJ
cord-256187-ofp7tupv	285	17	system	system	NN
cord-256187-ofp7tupv	285	18	as	as	IN
cord-256187-ofp7tupv	285	19	,	,	,
cord-256187-ofp7tupv	285	20	for	for	IN
cord-256187-ofp7tupv	285	21	example	example	NN
cord-256187-ofp7tupv	285	22	the	the	DT
cord-256187-ofp7tupv	285	23	shedded	shedde	VBN
cord-256187-ofp7tupv	285	24	form	form	NN
cord-256187-ofp7tupv	285	25	of	of	IN
cord-256187-ofp7tupv	285	26	GP	GP	NNP
cord-256187-ofp7tupv	285	27	might	may	MD
cord-256187-ofp7tupv	285	28	be	be	VB
cord-256187-ofp7tupv	285	29	able	able	JJ
cord-256187-ofp7tupv	285	30	to	to	TO
cord-256187-ofp7tupv	285	31	act	act	VB
cord-256187-ofp7tupv	285	32	as	as	IN
cord-256187-ofp7tupv	285	33	a	a	DT
cord-256187-ofp7tupv	285	34	decoy	decoy	NN
cord-256187-ofp7tupv	285	35	for	for	IN
cord-256187-ofp7tupv	285	36	neutralizing	neutralize	VBG
cord-256187-ofp7tupv	285	37	antibodies	antibody	NNS
cord-256187-ofp7tupv	285	38	(	(	-LRB-
cord-256187-ofp7tupv	285	39	Dolnik	Dolnik	NNP
cord-256187-ofp7tupv	285	40	et	et	FW
cord-256187-ofp7tupv	285	41	al	al	NNP
cord-256187-ofp7tupv	285	42	.	.	NNP
cord-256187-ofp7tupv	285	43	,	,	,
cord-256187-ofp7tupv	285	44	2008	2008	CD
cord-256187-ofp7tupv	285	45	)	)	-RRB-
cord-256187-ofp7tupv	285	46	.	.	.
cord-256187-ofp7tupv	286	1	However	however	RB
cord-256187-ofp7tupv	286	2	,	,	,
cord-256187-ofp7tupv	286	3	neither	neither	CC
cord-256187-ofp7tupv	286	4	sGP	sgp	XX
cord-256187-ofp7tupv	286	5	nor	nor	CC
cord-256187-ofp7tupv	286	6	GP	GP	NNP
cord-256187-ofp7tupv	286	7	1,2D	1,2d	CD
cord-256187-ofp7tupv	286	8	are	be	VBP
cord-256187-ofp7tupv	286	9	able	able	JJ
cord-256187-ofp7tupv	286	10	to	to	TO
cord-256187-ofp7tupv	286	11	counteract	counteract	VB
cord-256187-ofp7tupv	286	12	tetherin	tetherin	NNS
cord-256187-ofp7tupv	286	13	(	(	-LRB-
cord-256187-ofp7tupv	286	14	Kaletsky	Kaletsky	NNP
cord-256187-ofp7tupv	286	15	et	et	NNP
cord-256187-ofp7tupv	286	16	al	al	NNP
cord-256187-ofp7tupv	286	17	.	.	NNP
cord-256187-ofp7tupv	286	18	,	,	,
cord-256187-ofp7tupv	286	19	2009	2009	CD
cord-256187-ofp7tupv	286	20	)	)	-RRB-
cord-256187-ofp7tupv	286	21	.	.	.
cord-256187-ofp7tupv	287	1	In	in	IN
cord-256187-ofp7tupv	287	2	addition	addition	NN
cord-256187-ofp7tupv	287	3	,	,	,
cord-256187-ofp7tupv	287	4	a	a	DT
cord-256187-ofp7tupv	287	5	GP	gp	NN
cord-256187-ofp7tupv	287	6	1,2	1,2	CD
cord-256187-ofp7tupv	287	7	mutant	mutant	JJ
cord-256187-ofp7tupv	287	8	that	that	WDT
cord-256187-ofp7tupv	287	9	is	be	VBZ
cord-256187-ofp7tupv	287	10	retained	retain	VBN
cord-256187-ofp7tupv	287	11	in	in	IN
cord-256187-ofp7tupv	287	12	the	the	DT
cord-256187-ofp7tupv	287	13	ER	ER	NNP
cord-256187-ofp7tupv	287	14	failed	fail	VBD
cord-256187-ofp7tupv	287	15	to	to	TO
cord-256187-ofp7tupv	287	16	counteract	counteract	VB
cord-256187-ofp7tupv	287	17	tetherin	tetherin	NNS
cord-256187-ofp7tupv	287	18	,	,	,
cord-256187-ofp7tupv	287	19	suggesting	suggest	VBG
cord-256187-ofp7tupv	287	20	that	that	IN
cord-256187-ofp7tupv	287	21	the	the	DT
cord-256187-ofp7tupv	287	22	correct	correct	JJ
cord-256187-ofp7tupv	287	23	localization	localization	NN
cord-256187-ofp7tupv	287	24	of	of	IN
cord-256187-ofp7tupv	287	25	the	the	DT
cord-256187-ofp7tupv	287	26	EBOV	EBOV	NNP
cord-256187-ofp7tupv	287	27	-	-	HYPH
cord-256187-ofp7tupv	287	28	GP	GP	NNP
cord-256187-ofp7tupv	287	29	1,2	1,2	CD
cord-256187-ofp7tupv	287	30	at	at	IN
cord-256187-ofp7tupv	287	31	sites	site	NNS
cord-256187-ofp7tupv	287	32	of	of	IN
cord-256187-ofp7tupv	287	33	viral	viral	JJ
cord-256187-ofp7tupv	287	34	budding	budding	NN
cord-256187-ofp7tupv	287	35	is	be	VBZ
cord-256187-ofp7tupv	287	36	crucial	crucial	JJ
cord-256187-ofp7tupv	287	37	for	for	IN
cord-256187-ofp7tupv	287	38	tetherin	tetherin	NNP
cord-256187-ofp7tupv	287	39	antagonism	antagonism	NN
cord-256187-ofp7tupv	288	1	(	(	-LRB-
cord-256187-ofp7tupv	288	2	Kaletsky	Kaletsky	NNP
cord-256187-ofp7tupv	288	3	et	et	NNP
cord-256187-ofp7tupv	288	4	al	al	NNP
cord-256187-ofp7tupv	288	5	.	.	NNP
cord-256187-ofp7tupv	288	6	,	,	,
cord-256187-ofp7tupv	288	7	2009	2009	CD
cord-256187-ofp7tupv	288	8	)	)	-RRB-
cord-256187-ofp7tupv	288	9	.	.	.
cord-256187-ofp7tupv	289	1	Indeed	indeed	RB
cord-256187-ofp7tupv	289	2	,	,	,
cord-256187-ofp7tupv	289	3	because	because	IN
cord-256187-ofp7tupv	289	4	of	of	IN
cord-256187-ofp7tupv	289	5	the	the	DT
cord-256187-ofp7tupv	289	6	expression	expression	NN
cord-256187-ofp7tupv	289	7	of	of	IN
cord-256187-ofp7tupv	289	8	the	the	DT
cord-256187-ofp7tupv	289	9	GPI	GPI	NNP
cord-256187-ofp7tupv	289	10	-	-	HYPH
cord-256187-ofp7tupv	289	11	anchor	anchor	NN
cord-256187-ofp7tupv	289	12	,	,	,
cord-256187-ofp7tupv	289	13	tetherin	tetherin	NNP
cord-256187-ofp7tupv	289	14	is	be	VBZ
cord-256187-ofp7tupv	289	15	localized	localize	VBN
cord-256187-ofp7tupv	289	16	to	to	IN
cord-256187-ofp7tupv	289	17	lipid	lipid	NN
cord-256187-ofp7tupv	289	18	rafts	raft	NNS
cord-256187-ofp7tupv	289	19	,	,	,
cord-256187-ofp7tupv	289	20	which	which	WDT
cord-256187-ofp7tupv	289	21	are	be	VBP
cord-256187-ofp7tupv	289	22	used	use	VBN
cord-256187-ofp7tupv	289	23	by	by	IN
cord-256187-ofp7tupv	289	24	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	289	25	and	and	CC
cord-256187-ofp7tupv	289	26	EBOV	EBOV	NNP
cord-256187-ofp7tupv	289	27	as	as	IN
cord-256187-ofp7tupv	289	28	platforms	platform	NNS
cord-256187-ofp7tupv	289	29	for	for	IN
cord-256187-ofp7tupv	289	30	budding	bud	VBG
cord-256187-ofp7tupv	290	1	(	(	-LRB-
cord-256187-ofp7tupv	290	2	Ono	Ono	NNP
cord-256187-ofp7tupv	290	3	and	and	CC
cord-256187-ofp7tupv	290	4	Freed	Freed	NNP
cord-256187-ofp7tupv	290	5	,	,	,
cord-256187-ofp7tupv	290	6	2001	2001	CD
cord-256187-ofp7tupv	290	7	;	;	:
cord-256187-ofp7tupv	290	8	Bavari	Bavari	NNP
cord-256187-ofp7tupv	290	9	et	et	NNP
cord-256187-ofp7tupv	290	10	al	al	NNP
cord-256187-ofp7tupv	290	11	.	.	NNP
cord-256187-ofp7tupv	290	12	,	,	,
cord-256187-ofp7tupv	290	13	2002	2002	CD
cord-256187-ofp7tupv	290	14	)	)	-RRB-
cord-256187-ofp7tupv	290	15	.	.	.
cord-256187-ofp7tupv	291	1	Vpu	Vpu	NNP
cord-256187-ofp7tupv	291	2	and	and	CC
cord-256187-ofp7tupv	291	3	tetherin	tetherin	XX
cord-256187-ofp7tupv	291	4	interact	interact	VBP
cord-256187-ofp7tupv	291	5	via	via	IN
cord-256187-ofp7tupv	291	6	their	-PRON-	PRP$
cord-256187-ofp7tupv	291	7	TM	TM	NNP
cord-256187-ofp7tupv	291	8	domains	domain	NNS
cord-256187-ofp7tupv	291	9	,	,	,
cord-256187-ofp7tupv	291	10	and	and	CC
cord-256187-ofp7tupv	291	11	the	the	DT
cord-256187-ofp7tupv	291	12	interaction	interaction	NN
cord-256187-ofp7tupv	291	13	is	be	VBZ
cord-256187-ofp7tupv	291	14	critical	critical	JJ
cord-256187-ofp7tupv	291	15	for	for	IN
cord-256187-ofp7tupv	291	16	tetherin	tetherin	NNP
cord-256187-ofp7tupv	291	17	antagonism	antagonism	NN
cord-256187-ofp7tupv	291	18	.	.	.
cord-256187-ofp7tupv	292	1	In	in	IN
cord-256187-ofp7tupv	292	2	contrast	contrast	NN
cord-256187-ofp7tupv	292	3	,	,	,
cord-256187-ofp7tupv	292	4	the	the	DT
cord-256187-ofp7tupv	292	5	sequences	sequence	NNS
cord-256187-ofp7tupv	292	6	of	of	IN
cord-256187-ofp7tupv	292	7	tetherin	tetherin	NNP
cord-256187-ofp7tupv	292	8	's	's	POS
cord-256187-ofp7tupv	292	9	cytoplasmic	cytoplasmic	JJ
cord-256187-ofp7tupv	292	10	tail	tail	NN
cord-256187-ofp7tupv	292	11	(	(	-LRB-
cord-256187-ofp7tupv	292	12	CT	CT	NNP
cord-256187-ofp7tupv	292	13	)	)	-RRB-
cord-256187-ofp7tupv	292	14	and	and	CC
cord-256187-ofp7tupv	292	15	TM	TM	NNP
cord-256187-ofp7tupv	292	16	domain	domain	NN
cord-256187-ofp7tupv	292	17	do	do	VBP
cord-256187-ofp7tupv	292	18	not	not	RB
cord-256187-ofp7tupv	292	19	determine	determine	VB
cord-256187-ofp7tupv	292	20	counteraction	counteraction	NN
cord-256187-ofp7tupv	292	21	by	by	IN
cord-256187-ofp7tupv	292	22	EBOV	EBOV	NNP
cord-256187-ofp7tupv	292	23	-	-	HYPH
cord-256187-ofp7tupv	292	24	GP	GP	NNP
cord-256187-ofp7tupv	292	25	1,2	1,2	CD
cord-256187-ofp7tupv	292	26	.	.	.
cord-256187-ofp7tupv	293	1	Thus	thus	RB
cord-256187-ofp7tupv	293	2	,	,	,
cord-256187-ofp7tupv	293	3	tetherin	tetherin	NNP
cord-256187-ofp7tupv	293	4	chimeras	chimera	NNS
cord-256187-ofp7tupv	293	5	in	in	IN
cord-256187-ofp7tupv	293	6	which	which	WDT
cord-256187-ofp7tupv	293	7	the	the	DT
cord-256187-ofp7tupv	293	8	TM	TM	NNP
cord-256187-ofp7tupv	293	9	region	region	NN
cord-256187-ofp7tupv	293	10	and	and	CC
cord-256187-ofp7tupv	293	11	the	the	DT
cord-256187-ofp7tupv	293	12	N	N	NNP
cord-256187-ofp7tupv	293	13	-	-	HYPH
cord-256187-ofp7tupv	293	14	terminus	terminus	NN
cord-256187-ofp7tupv	293	15	of	of	IN
cord-256187-ofp7tupv	293	16	tetherin	tetherin	NNP
cord-256187-ofp7tupv	293	17	were	be	VBD
cord-256187-ofp7tupv	293	18	exchanged	exchange	VBN
cord-256187-ofp7tupv	293	19	against	against	IN
cord-256187-ofp7tupv	293	20	similar	similar	JJ
cord-256187-ofp7tupv	293	21	domains	domain	NNS
cord-256187-ofp7tupv	293	22	of	of	IN
cord-256187-ofp7tupv	293	23	the	the	DT
cord-256187-ofp7tupv	293	24	transferrin	transferrin	NN
cord-256187-ofp7tupv	293	25	receptor	receptor	NN
cord-256187-ofp7tupv	293	26	type	type	NN
cord-256187-ofp7tupv	293	27	1	1	CD
cord-256187-ofp7tupv	293	28	(	(	-LRB-
cord-256187-ofp7tupv	293	29	TfR	TfR	NNP
cord-256187-ofp7tupv	293	30	)	)	-RRB-
cord-256187-ofp7tupv	293	31	displayed	display	VBN
cord-256187-ofp7tupv	293	32	antiviral	antiviral	JJ
cord-256187-ofp7tupv	293	33	activity	activity	NN
cord-256187-ofp7tupv	293	34	and	and	CC
cord-256187-ofp7tupv	293	35	were	be	VBD
cord-256187-ofp7tupv	293	36	counteracted	counteract	VBN
cord-256187-ofp7tupv	293	37	by	by	IN
cord-256187-ofp7tupv	293	38	EBOV	EBOV	NNP
cord-256187-ofp7tupv	293	39	-	-	HYPH
cord-256187-ofp7tupv	293	40	GP	GP	NNP
cord-256187-ofp7tupv	293	41	1,2	1,2	CD
cord-256187-ofp7tupv	294	1	(	(	-LRB-
cord-256187-ofp7tupv	294	2	Lopez	Lopez	NNP
cord-256187-ofp7tupv	294	3	et	et	NNP
cord-256187-ofp7tupv	294	4	al	al	NNP
cord-256187-ofp7tupv	294	5	.	.	NNP
cord-256187-ofp7tupv	294	6	,	,	,
cord-256187-ofp7tupv	294	7	2010	2010	CD
cord-256187-ofp7tupv	294	8	)	)	-RRB-
cord-256187-ofp7tupv	294	9	.	.	.
cord-256187-ofp7tupv	295	1	Nevertheless	nevertheless	RB
cord-256187-ofp7tupv	295	2	,	,	,
cord-256187-ofp7tupv	295	3	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	295	4	-	-	HYPH
cord-256187-ofp7tupv	295	5	GP	GP	NNP
cord-256187-ofp7tupv	295	6	1,2	1,2	CD
cord-256187-ofp7tupv	295	7	is	be	VBZ
cord-256187-ofp7tupv	295	8	able	able	JJ
cord-256187-ofp7tupv	295	9	to	to	TO
cord-256187-ofp7tupv	295	10	efficiently	efficiently	RB
cord-256187-ofp7tupv	295	11	coimmunoprecipitate	coimmunoprecipitate	VB
cord-256187-ofp7tupv	295	12	human	human	JJ
cord-256187-ofp7tupv	295	13	tetherin	tetherin	NN
cord-256187-ofp7tupv	295	14	(	(	-LRB-
cord-256187-ofp7tupv	295	15	Kaletsky	Kaletsky	NNP
cord-256187-ofp7tupv	295	16	et	et	NNP
cord-256187-ofp7tupv	295	17	al	al	NNP
cord-256187-ofp7tupv	295	18	.	.	NNP
cord-256187-ofp7tupv	295	19	,	,	,
cord-256187-ofp7tupv	295	20	2009	2009	CD
cord-256187-ofp7tupv	295	21	)	)	-RRB-
cord-256187-ofp7tupv	295	22	,	,	,
cord-256187-ofp7tupv	295	23	and	and	CC
cord-256187-ofp7tupv	295	24	the	the	DT
cord-256187-ofp7tupv	295	25	GP	GP	NNP
cord-256187-ofp7tupv	295	26	2	2	CD
cord-256187-ofp7tupv	295	27	subunit	subunit	NN
cord-256187-ofp7tupv	295	28	of	of	IN
cord-256187-ofp7tupv	295	29	EBOV	EBOV	NNP
cord-256187-ofp7tupv	295	30	-	-	HYPH
cord-256187-ofp7tupv	295	31	GP	GP	NNP
cord-256187-ofp7tupv	295	32	1,2	1,2	CD
cord-256187-ofp7tupv	295	33	was	be	VBD
cord-256187-ofp7tupv	295	34	shown	show	VBN
cord-256187-ofp7tupv	295	35	to	to	TO
cord-256187-ofp7tupv	295	36	be	be	VB
cord-256187-ofp7tupv	295	37	critical	critical	JJ
cord-256187-ofp7tupv	295	38	for	for	IN
cord-256187-ofp7tupv	295	39	the	the	DT
cord-256187-ofp7tupv	295	40	interaction	interaction	NN
cord-256187-ofp7tupv	295	41	(	(	-LRB-
cord-256187-ofp7tupv	295	42	Kühl	Kühl	NNP
cord-256187-ofp7tupv	295	43	et	et	FW
cord-256187-ofp7tupv	295	44	al	al	NNP
cord-256187-ofp7tupv	295	45	.	.	NNP
cord-256187-ofp7tupv	295	46	,	,	,
cord-256187-ofp7tupv	295	47	2011a	2011a	CD
cord-256187-ofp7tupv	295	48	)	)	-RRB-
cord-256187-ofp7tupv	295	49	.	.	.
cord-256187-ofp7tupv	296	1	Which	which	WDT
cord-256187-ofp7tupv	296	2	domain	domain	NN
cord-256187-ofp7tupv	296	3	of	of	IN
cord-256187-ofp7tupv	296	4	tetherin	tetherin	NNP
cord-256187-ofp7tupv	296	5	interacts	interact	VBZ
cord-256187-ofp7tupv	296	6	with	with	IN
cord-256187-ofp7tupv	296	7	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	296	8	-	-	HYPH
cord-256187-ofp7tupv	296	9	GP	GP	NNP
cord-256187-ofp7tupv	296	10	2	2	CD
cord-256187-ofp7tupv	296	11	remains	remain	VBZ
cord-256187-ofp7tupv	296	12	to	to	TO
cord-256187-ofp7tupv	296	13	be	be	VB
cord-256187-ofp7tupv	296	14	determined	determine	VBN
cord-256187-ofp7tupv	296	15	,	,	,
cord-256187-ofp7tupv	296	16	and	and	CC
cord-256187-ofp7tupv	296	17	,	,	,
cord-256187-ofp7tupv	296	18	because	because	IN
cord-256187-ofp7tupv	296	19	of	of	IN
cord-256187-ofp7tupv	296	20	topological	topological	JJ
cord-256187-ofp7tupv	296	21	constraints	constraint	NNS
cord-256187-ofp7tupv	296	22	,	,	,
cord-256187-ofp7tupv	296	23	the	the	DT
cord-256187-ofp7tupv	296	24	TM	TM	NNP
cord-256187-ofp7tupv	296	25	unit	unit	NN
cord-256187-ofp7tupv	296	26	and	and	CC
cord-256187-ofp7tupv	296	27	the	the	DT
cord-256187-ofp7tupv	296	28	CT	CT	NNP
cord-256187-ofp7tupv	296	29	are	be	VBP
cord-256187-ofp7tupv	296	30	interesting	interesting	JJ
cord-256187-ofp7tupv	296	31	candidates	candidate	NNS
cord-256187-ofp7tupv	296	32	.	.	.
cord-256187-ofp7tupv	297	1	However	however	RB
cord-256187-ofp7tupv	297	2	,	,	,
cord-256187-ofp7tupv	297	3	the	the	DT
cord-256187-ofp7tupv	297	4	TM	TM	NNP
cord-256187-ofp7tupv	297	5	and	and	CC
cord-256187-ofp7tupv	297	6	CT	CT	NNP
cord-256187-ofp7tupv	297	7	have	have	VBP
cord-256187-ofp7tupv	297	8	been	be	VBN
cord-256187-ofp7tupv	297	9	shown	show	VBN
cord-256187-ofp7tupv	297	10	to	to	TO
cord-256187-ofp7tupv	297	11	be	be	VB
cord-256187-ofp7tupv	297	12	irrelevant	irrelevant	JJ
cord-256187-ofp7tupv	297	13	for	for	IN
cord-256187-ofp7tupv	297	14	tetherin	tetherin	NN
cord-256187-ofp7tupv	297	15	counteraction	counteraction	NN
cord-256187-ofp7tupv	297	16	by	by	IN
cord-256187-ofp7tupv	297	17	ZEBOV	ZEBOV	NNP
cord-256187-ofp7tupv	297	18	-	-	HYPH
cord-256187-ofp7tupv	297	19	GP	GP	NNP
cord-256187-ofp7tupv	297	20	1,2	1,2	CD
cord-256187-ofp7tupv	298	1	(	(	-LRB-
cord-256187-ofp7tupv	298	2	Lopez	Lopez	NNP
cord-256187-ofp7tupv	298	3	et	et	NNP
cord-256187-ofp7tupv	298	4	al	al	NNP
cord-256187-ofp7tupv	298	5	.	.	NNP
cord-256187-ofp7tupv	298	6	,	,	,
cord-256187-ofp7tupv	298	7	2010	2010	CD
cord-256187-ofp7tupv	298	8	)	)	-RRB-
cord-256187-ofp7tupv	298	9	,	,	,
cord-256187-ofp7tupv	298	10	and	and	CC
cord-256187-ofp7tupv	298	11	the	the	DT
cord-256187-ofp7tupv	298	12	importance	importance	NN
cord-256187-ofp7tupv	298	13	of	of	IN
cord-256187-ofp7tupv	298	14	tetherin	tetherin	NNP
cord-256187-ofp7tupv	298	15	binding	bind	VBG
cord-256187-ofp7tupv	298	16	for	for	IN
cord-256187-ofp7tupv	298	17	tetherin	tetherin	NN
cord-256187-ofp7tupv	298	18	inhibition	inhibition	NN
cord-256187-ofp7tupv	298	19	by	by	IN
cord-256187-ofp7tupv	298	20	EBOV	EBOV	NNP
cord-256187-ofp7tupv	298	21	-	-	HYPH
cord-256187-ofp7tupv	298	22	GP	GP	NNP
cord-256187-ofp7tupv	298	23	1,2	1,2	CD
cord-256187-ofp7tupv	298	24	remains	remain	VBZ
cord-256187-ofp7tupv	298	25	to	to	TO
cord-256187-ofp7tupv	298	26	be	be	VB
cord-256187-ofp7tupv	298	27	determined	determine	VBN
cord-256187-ofp7tupv	298	28	.	.	.
cord-256187-ofp7tupv	299	1	The	the	DT
cord-256187-ofp7tupv	299	2	EBOV	EBOV	NNP
cord-256187-ofp7tupv	299	3	-	-	HYPH
cord-256187-ofp7tupv	299	4	GP	GP	NNP
cord-256187-ofp7tupv	299	5	1,2	1,2	CD
cord-256187-ofp7tupv	299	6	might	may	MD
cord-256187-ofp7tupv	299	7	relocalize	relocalize	VB
cord-256187-ofp7tupv	299	8	tetherin	tetherin	NNS
cord-256187-ofp7tupv	299	9	within	within	IN
cord-256187-ofp7tupv	299	10	the	the	DT
cord-256187-ofp7tupv	299	11	plasma	plasma	NN
cord-256187-ofp7tupv	299	12	membrane	membrane	NN
cord-256187-ofp7tupv	299	13	or	or	CC
cord-256187-ofp7tupv	299	14	interfere	interfere	VB
cord-256187-ofp7tupv	299	15	with	with	IN
cord-256187-ofp7tupv	299	16	the	the	DT
cord-256187-ofp7tupv	299	17	structural	structural	JJ
cord-256187-ofp7tupv	299	18	integrity	integrity	NN
cord-256187-ofp7tupv	299	19	of	of	IN
cord-256187-ofp7tupv	299	20	tetherin	tetherin	NNP
cord-256187-ofp7tupv	299	21	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	299	22	and	and	CC
cord-256187-ofp7tupv	299	23	VP40	VP40	NNP
cord-256187-ofp7tupv	299	24	,	,	,
cord-256187-ofp7tupv	299	25	which	which	WDT
cord-256187-ofp7tupv	299	26	is	be	VBZ
cord-256187-ofp7tupv	299	27	essential	essential	JJ
cord-256187-ofp7tupv	299	28	for	for	IN
cord-256187-ofp7tupv	299	29	EBOV	EBOV	NNP
cord-256187-ofp7tupv	299	30	budding	bud	VBG
cord-256187-ofp7tupv	299	31	,	,	,
cord-256187-ofp7tupv	300	1	colocalize	colocalize	NNP
cord-256187-ofp7tupv	300	2	at	at	IN
cord-256187-ofp7tupv	300	3	the	the	DT
cord-256187-ofp7tupv	300	4	plasma	plasma	NN
cord-256187-ofp7tupv	300	5	membrane	membrane	NN
cord-256187-ofp7tupv	300	6	and	and	CC
cord-256187-ofp7tupv	300	7	release	release	NN
cord-256187-ofp7tupv	300	8	of	of	IN
cord-256187-ofp7tupv	300	9	VP40based	VP40based	NNP
cord-256187-ofp7tupv	300	10	VLPs	vlp	NNS
cord-256187-ofp7tupv	300	11	is	be	VBZ
cord-256187-ofp7tupv	300	12	inhibited	inhibit	VBN
cord-256187-ofp7tupv	300	13	by	by	IN
cord-256187-ofp7tupv	300	14	tetherin	tetherin	FW
cord-256187-ofp7tupv	300	15	(	(	-LRB-
cord-256187-ofp7tupv	300	16	Jouvenet	Jouvenet	NNP
cord-256187-ofp7tupv	300	17	et	et	NNP
cord-256187-ofp7tupv	300	18	al	al	NNP
cord-256187-ofp7tupv	300	19	.	.	NNP
cord-256187-ofp7tupv	300	20	,	,	,
cord-256187-ofp7tupv	300	21	2009	2009	CD
cord-256187-ofp7tupv	300	22	)	)	-RRB-
cord-256187-ofp7tupv	300	23	.	.	.
cord-256187-ofp7tupv	301	1	It	-PRON-	PRP
cord-256187-ofp7tupv	301	2	is	be	VBZ
cord-256187-ofp7tupv	301	3	thus	thus	RB
cord-256187-ofp7tupv	301	4	possible	possible	JJ
cord-256187-ofp7tupv	301	5	that	that	IN
cord-256187-ofp7tupv	301	6	the	the	DT
cord-256187-ofp7tupv	301	7	EBOV	EBOV	NNP
cord-256187-ofp7tupv	301	8	-	-	HYPH
cord-256187-ofp7tupv	301	9	GP	GP	NNP
cord-256187-ofp7tupv	301	10	1,2	1,2	CD
cord-256187-ofp7tupv	301	11	rescues	rescue	VBZ
cord-256187-ofp7tupv	301	12	the	the	DT
cord-256187-ofp7tupv	301	13	block	block	NN
cord-256187-ofp7tupv	301	14	to	to	IN
cord-256187-ofp7tupv	301	15	particle	particle	NN
cord-256187-ofp7tupv	301	16	release	release	NN
cord-256187-ofp7tupv	301	17	by	by	IN
cord-256187-ofp7tupv	301	18	interfering	interfere	VBG
cord-256187-ofp7tupv	301	19	with	with	IN
cord-256187-ofp7tupv	301	20	the	the	DT
cord-256187-ofp7tupv	301	21	integrity	integrity	NN
cord-256187-ofp7tupv	301	22	of	of	IN
cord-256187-ofp7tupv	301	23	tetherin	tetherin	NNP
cord-256187-ofp7tupv	301	24	at	at	IN
cord-256187-ofp7tupv	301	25	filoviral	filoviral	JJ
cord-256187-ofp7tupv	301	26	budding	bud	VBG
cord-256187-ofp7tupv	301	27	sites	site	NNS
cord-256187-ofp7tupv	302	1	(	(	-LRB-
cord-256187-ofp7tupv	302	2	Kühl	Kühl	NNP
cord-256187-ofp7tupv	302	3	et	et	FW
cord-256187-ofp7tupv	302	4	al	al	NNP
cord-256187-ofp7tupv	302	5	.	.	NNP
cord-256187-ofp7tupv	302	6	,	,	,
cord-256187-ofp7tupv	302	7	2011a	2011a	CD
cord-256187-ofp7tupv	302	8	)	)	-RRB-
cord-256187-ofp7tupv	302	9	.	.	.
cord-256187-ofp7tupv	303	1	Alternatively	alternatively	RB
cord-256187-ofp7tupv	303	2	,	,	,
cord-256187-ofp7tupv	303	3	the	the	DT
cord-256187-ofp7tupv	303	4	extracellular	extracellular	JJ
cord-256187-ofp7tupv	303	5	,	,	,
cord-256187-ofp7tupv	303	6	heavily	heavily	RB
cord-256187-ofp7tupv	303	7	glycosylated	glycosylated	JJ
cord-256187-ofp7tupv	303	8	EBOV	EBOV	NNP
cord-256187-ofp7tupv	303	9	-	-	HYPH
cord-256187-ofp7tupv	303	10	GP	GP	NNP
cord-256187-ofp7tupv	303	11	1	1	CD
cord-256187-ofp7tupv	303	12	subunit	subunit	NN
cord-256187-ofp7tupv	303	13	might	may	MD
cord-256187-ofp7tupv	303	14	interfere	interfere	VB
cord-256187-ofp7tupv	303	15	with	with	IN
cord-256187-ofp7tupv	303	16	the	the	DT
cord-256187-ofp7tupv	303	17	formation	formation	NN
cord-256187-ofp7tupv	303	18	of	of	IN
cord-256187-ofp7tupv	303	19	the	the	DT
cord-256187-ofp7tupv	303	20	'	'	``
cord-256187-ofp7tupv	303	21	tetherin	tetherin	NN
cord-256187-ofp7tupv	303	22	-	-	HYPH
cord-256187-ofp7tupv	303	23	clamp	clamp	NN
cord-256187-ofp7tupv	303	24	'	'	''
cord-256187-ofp7tupv	303	25	between	between	IN
cord-256187-ofp7tupv	303	26	the	the	DT
cord-256187-ofp7tupv	303	27	cellular	cellular	NN
cord-256187-ofp7tupv	303	28	and	and	CC
cord-256187-ofp7tupv	303	29	the	the	DT
cord-256187-ofp7tupv	303	30	viral	viral	JJ
cord-256187-ofp7tupv	303	31	membrane	membrane	NN
cord-256187-ofp7tupv	303	32	,	,	,
cord-256187-ofp7tupv	303	33	because	because	IN
cord-256187-ofp7tupv	303	34	of	of	IN
cord-256187-ofp7tupv	303	35	steric	steric	JJ
cord-256187-ofp7tupv	303	36	hindrance	hindrance	NN
cord-256187-ofp7tupv	303	37	.	.	.
cord-256187-ofp7tupv	304	1	Finally	finally	RB
cord-256187-ofp7tupv	304	2	,	,	,
cord-256187-ofp7tupv	304	3	EBOV	EBOV	NNP
cord-256187-ofp7tupv	304	4	-	-	HYPH
cord-256187-ofp7tupv	304	5	GP	GP	NNP
cord-256187-ofp7tupv	304	6	1,2	1,2	CD
cord-256187-ofp7tupv	304	7	might	may	MD
cord-256187-ofp7tupv	304	8	relocalize	relocalize	VB
cord-256187-ofp7tupv	304	9	tetherin	tetherin	NNS
cord-256187-ofp7tupv	304	10	within	within	IN
cord-256187-ofp7tupv	304	11	the	the	DT
cord-256187-ofp7tupv	304	12	plasma	plasma	NN
cord-256187-ofp7tupv	304	13	membrane	membrane	NN
cord-256187-ofp7tupv	304	14	,	,	,
cord-256187-ofp7tupv	304	15	thereby	thereby	RB
cord-256187-ofp7tupv	304	16	excluding	exclude	VBG
cord-256187-ofp7tupv	304	17	it	-PRON-	PRP
cord-256187-ofp7tupv	304	18	from	from	IN
cord-256187-ofp7tupv	304	19	membrane	membrane	NN
cord-256187-ofp7tupv	304	20	domains	domain	NNS
cord-256187-ofp7tupv	304	21	used	use	VBN
cord-256187-ofp7tupv	304	22	by	by	IN
cord-256187-ofp7tupv	304	23	EBOV	EBOV	NNP
cord-256187-ofp7tupv	304	24	for	for	IN
cord-256187-ofp7tupv	304	25	budding	bud	VBG
cord-256187-ofp7tupv	304	26	.	.	.
cord-256187-ofp7tupv	305	1	Indeed	indeed	RB
cord-256187-ofp7tupv	305	2	,	,	,
cord-256187-ofp7tupv	305	3	it	-PRON-	PRP
cord-256187-ofp7tupv	305	4	was	be	VBD
cord-256187-ofp7tupv	305	5	observed	observe	VBN
cord-256187-ofp7tupv	305	6	that	that	IN
cord-256187-ofp7tupv	305	7	tetherin	tetherin	NNP
cord-256187-ofp7tupv	305	8	is	be	VBZ
cord-256187-ofp7tupv	305	9	excluded	exclude	VBN
cord-256187-ofp7tupv	305	10	from	from	IN
cord-256187-ofp7tupv	305	11	plasma	plasma	NN
cord-256187-ofp7tupv	305	12	membrane	membrane	NN
cord-256187-ofp7tupv	305	13	sites	site	NNS
cord-256187-ofp7tupv	305	14	positive	positive	JJ
cord-256187-ofp7tupv	305	15	for	for	IN
cord-256187-ofp7tupv	305	16	GP	GP	NNP
cord-256187-ofp7tupv	305	17	1,2	1,2	CD
cord-256187-ofp7tupv	305	18	in	in	IN
cord-256187-ofp7tupv	305	19	EBOV	EBOV	NNP
cord-256187-ofp7tupv	305	20	-	-	HYPH
cord-256187-ofp7tupv	305	21	infected	infect	VBN
cord-256187-ofp7tupv	305	22	cells	cell	NNS
cord-256187-ofp7tupv	306	1	(	(	-LRB-
cord-256187-ofp7tupv	306	2	Radoshitzky	Radoshitzky	NNP
cord-256187-ofp7tupv	306	3	et	et	NNP
cord-256187-ofp7tupv	306	4	al	al	NNP
cord-256187-ofp7tupv	306	5	.	.	NNP
cord-256187-ofp7tupv	306	6	,	,	,
cord-256187-ofp7tupv	306	7	2010	2010	CD
cord-256187-ofp7tupv	306	8	)	)	-RRB-
cord-256187-ofp7tupv	306	9	,	,	,
cord-256187-ofp7tupv	306	10	lending	lend	VBG
cord-256187-ofp7tupv	306	11	support	support	NN
cord-256187-ofp7tupv	306	12	to	to	IN
cord-256187-ofp7tupv	306	13	the	the	DT
cord-256187-ofp7tupv	306	14	idea	idea	NN
cord-256187-ofp7tupv	306	15	that	that	IN
cord-256187-ofp7tupv	306	16	EBOV	EBOV	NNP
cord-256187-ofp7tupv	306	17	-	-	HYPH
cord-256187-ofp7tupv	306	18	GP	GP	NNP
cord-256187-ofp7tupv	306	19	1,2	1,2	CD
cord-256187-ofp7tupv	306	20	blocks	block	VBZ
cord-256187-ofp7tupv	306	21	tetherin	tetherin	NNP
cord-256187-ofp7tupv	306	22	's	's	POS
cord-256187-ofp7tupv	306	23	antiviral	antiviral	JJ
cord-256187-ofp7tupv	306	24	action	action	NN
cord-256187-ofp7tupv	306	25	by	by	IN
cord-256187-ofp7tupv	306	26	inducing	induce	VBG
cord-256187-ofp7tupv	306	27	its	-PRON-	PRP$
cord-256187-ofp7tupv	306	28	mislocalization	mislocalization	NN
cord-256187-ofp7tupv	306	29	within	within	IN
cord-256187-ofp7tupv	306	30	the	the	DT
cord-256187-ofp7tupv	306	31	plasma	plasma	NN
cord-256187-ofp7tupv	306	32	membrane	membrane	NN
cord-256187-ofp7tupv	306	33	.	.	.
cord-256187-ofp7tupv	307	1	Regardless	regardless	RB
cord-256187-ofp7tupv	307	2	of	of	IN
cord-256187-ofp7tupv	307	3	the	the	DT
cord-256187-ofp7tupv	307	4	mechanism	mechanism	NN
cord-256187-ofp7tupv	307	5	underlying	underlie	VBG
cord-256187-ofp7tupv	307	6	tetherin	tetherin	NN
cord-256187-ofp7tupv	307	7	counteraction	counteraction	NN
cord-256187-ofp7tupv	307	8	by	by	IN
cord-256187-ofp7tupv	307	9	EBOV	EBOV	NNP
cord-256187-ofp7tupv	307	10	-	-	HYPH
cord-256187-ofp7tupv	307	11	GP	GP	NNP
cord-256187-ofp7tupv	307	12	1,2	1,2	CD
cord-256187-ofp7tupv	307	13	,	,	,
cord-256187-ofp7tupv	307	14	it	-PRON-	PRP
cord-256187-ofp7tupv	307	15	remains	remain	VBZ
cord-256187-ofp7tupv	307	16	to	to	TO
cord-256187-ofp7tupv	307	17	be	be	VB
cord-256187-ofp7tupv	307	18	determined	determine	VBN
cord-256187-ofp7tupv	307	19	whether	whether	IN
cord-256187-ofp7tupv	307	20	endogenous	endogenous	JJ
cord-256187-ofp7tupv	307	21	tetherin	tetherin	NNS
cord-256187-ofp7tupv	307	22	can	can	MD
cord-256187-ofp7tupv	307	23	reduce	reduce	VB
cord-256187-ofp7tupv	307	24	EBOV	EBOV	NNP
cord-256187-ofp7tupv	307	25	release	release	NN
cord-256187-ofp7tupv	307	26	from	from	IN
cord-256187-ofp7tupv	307	27	infected	infected	JJ
cord-256187-ofp7tupv	307	28	cells	cell	NNS
cord-256187-ofp7tupv	307	29	,	,	,
cord-256187-ofp7tupv	307	30	as	as	IN
cord-256187-ofp7tupv	307	31	modest	modest	JJ
cord-256187-ofp7tupv	307	32	effects	effect	NNS
cord-256187-ofp7tupv	307	33	were	be	VBD
cord-256187-ofp7tupv	307	34	observed	observe	VBN
cord-256187-ofp7tupv	307	35	in	in	IN
cord-256187-ofp7tupv	307	36	one	one	CD
cord-256187-ofp7tupv	307	37	study	study	NN
cord-256187-ofp7tupv	307	38	(	(	-LRB-
cord-256187-ofp7tupv	307	39	Kühl	Kühl	NNP
cord-256187-ofp7tupv	307	40	et	et	FW
cord-256187-ofp7tupv	307	41	al	al	NNP
cord-256187-ofp7tupv	307	42	.	.	NNP
cord-256187-ofp7tupv	307	43	,	,	,
cord-256187-ofp7tupv	307	44	2011a	2011a	CD
cord-256187-ofp7tupv	307	45	)	)	-RRB-
cord-256187-ofp7tupv	307	46	but	but	CC
cord-256187-ofp7tupv	307	47	not	not	RB
cord-256187-ofp7tupv	307	48	in	in	IN
cord-256187-ofp7tupv	307	49	another	another	DT
cord-256187-ofp7tupv	307	50	applying	apply	VBG
cord-256187-ofp7tupv	307	51	a	a	DT
cord-256187-ofp7tupv	307	52	substantially	substantially	RB
cord-256187-ofp7tupv	307	53	higher	high	JJR
cord-256187-ofp7tupv	307	54	multiplicity	multiplicity	NN
cord-256187-ofp7tupv	307	55	of	of	IN
cord-256187-ofp7tupv	307	56	infection	infection	NN
cord-256187-ofp7tupv	307	57	(	(	-LRB-
cord-256187-ofp7tupv	307	58	MOI	MOI	NNP
cord-256187-ofp7tupv	307	59	)	)	-RRB-
cord-256187-ofp7tupv	308	1	(	(	-LRB-
cord-256187-ofp7tupv	308	2	Radoshitzky	Radoshitzky	NNP
cord-256187-ofp7tupv	308	3	et	et	NNP
cord-256187-ofp7tupv	308	4	al	al	NNP
cord-256187-ofp7tupv	308	5	.	.	NNP
cord-256187-ofp7tupv	308	6	,	,	,
cord-256187-ofp7tupv	308	7	2010	2010	CD
cord-256187-ofp7tupv	308	8	)	)	-RRB-
cord-256187-ofp7tupv	308	9	,	,	,
cord-256187-ofp7tupv	308	10	and	and	CC
cord-256187-ofp7tupv	308	11	might	may	MD
cord-256187-ofp7tupv	308	12	thus	thus	RB
cord-256187-ofp7tupv	308	13	restrict	restrict	VB
cord-256187-ofp7tupv	308	14	viral	viral	JJ
cord-256187-ofp7tupv	308	15	spread	spread	NN
cord-256187-ofp7tupv	308	16	in	in	IN
cord-256187-ofp7tupv	308	17	the	the	DT
cord-256187-ofp7tupv	308	18	infected	infected	JJ
cord-256187-ofp7tupv	308	19	host	host	NN
cord-256187-ofp7tupv	308	20	.	.	.
cord-256187-ofp7tupv	309	1	In	in	IN
cord-256187-ofp7tupv	309	2	addition	addition	NN
cord-256187-ofp7tupv	309	3	,	,	,
cord-256187-ofp7tupv	309	4	it	-PRON-	PRP
cord-256187-ofp7tupv	309	5	will	will	MD
cord-256187-ofp7tupv	309	6	be	be	VB
cord-256187-ofp7tupv	309	7	interesting	interesting	JJ
cord-256187-ofp7tupv	309	8	to	to	TO
cord-256187-ofp7tupv	309	9	determine	determine	VB
cord-256187-ofp7tupv	309	10	whether	whether	IN
cord-256187-ofp7tupv	309	11	African	african	JJ
cord-256187-ofp7tupv	309	12	fruit	fruit	NN
cord-256187-ofp7tupv	309	13	bats	bat	NNS
cord-256187-ofp7tupv	309	14	,	,	,
cord-256187-ofp7tupv	309	15	the	the	DT
cord-256187-ofp7tupv	309	16	potential	potential	JJ
cord-256187-ofp7tupv	309	17	natural	natural	JJ
cord-256187-ofp7tupv	309	18	reservoir	reservoir	NN
cord-256187-ofp7tupv	309	19	of	of	IN
cord-256187-ofp7tupv	309	20	EBOV	EBOV	NNP
cord-256187-ofp7tupv	309	21	,	,	,
cord-256187-ofp7tupv	309	22	encode	encode	VB
cord-256187-ofp7tupv	309	23	a	a	DT
cord-256187-ofp7tupv	309	24	tetherin	tetherin	NN
cord-256187-ofp7tupv	309	25	-	-	HYPH
cord-256187-ofp7tupv	309	26	like	like	JJ
cord-256187-ofp7tupv	309	27	protein	protein	NN
cord-256187-ofp7tupv	309	28	and	and	CC
cord-256187-ofp7tupv	309	29	whether	whether	IN
cord-256187-ofp7tupv	309	30	this	this	DT
cord-256187-ofp7tupv	309	31	tetherin	tetherin	FW
cord-256187-ofp7tupv	309	32	homologue	homologue	NN
cord-256187-ofp7tupv	309	33	restricts	restrict	VBZ
cord-256187-ofp7tupv	309	34	EBOV	EBOV	NNP
cord-256187-ofp7tupv	309	35	spread	spread	VBD
cord-256187-ofp7tupv	309	36	.	.	.
cord-256187-ofp7tupv	310	1	The	the	DT
cord-256187-ofp7tupv	310	2	IFITM	IFITM	NNP
cord-256187-ofp7tupv	310	3	1	1	CD
cord-256187-ofp7tupv	310	4	,	,	,
cord-256187-ofp7tupv	310	5	2	2	CD
cord-256187-ofp7tupv	310	6	and	and	CC
cord-256187-ofp7tupv	310	7	3	3	CD
cord-256187-ofp7tupv	310	8	were	be	VBD
cord-256187-ofp7tupv	310	9	recently	recently	RB
cord-256187-ofp7tupv	310	10	discovered	discover	VBN
cord-256187-ofp7tupv	310	11	as	as	IN
cord-256187-ofp7tupv	310	12	inhibitors	inhibitor	NNS
cord-256187-ofp7tupv	310	13	of	of	IN
cord-256187-ofp7tupv	310	14	host	host	NN
cord-256187-ofp7tupv	310	15	cell	cell	NN
cord-256187-ofp7tupv	310	16	entry	entry	NN
cord-256187-ofp7tupv	310	17	of	of	IN
cord-256187-ofp7tupv	310	18	several	several	JJ
cord-256187-ofp7tupv	310	19	enveloped	envelop	VBN
cord-256187-ofp7tupv	310	20	viruses	virus	NNS
cord-256187-ofp7tupv	310	21	,	,	,
cord-256187-ofp7tupv	310	22	including	include	VBG
cord-256187-ofp7tupv	310	23	EBOV	EBOV	NNP
cord-256187-ofp7tupv	310	24	(	(	-LRB-
cord-256187-ofp7tupv	310	25	Fig	Fig	NNP
cord-256187-ofp7tupv	310	26	.	.	NNP
cord-256187-ofp7tupv	310	27	5	5	CD
cord-256187-ofp7tupv	310	28	)	)	-RRB-
cord-256187-ofp7tupv	310	29	.	.	.
cord-256187-ofp7tupv	311	1	IFITMs	ifitms	RB
cord-256187-ofp7tupv	311	2	1	1	CD
cord-256187-ofp7tupv	311	3	,	,	,
cord-256187-ofp7tupv	311	4	2	2	CD
cord-256187-ofp7tupv	311	5	and	and	CC
cord-256187-ofp7tupv	311	6	3	3	CD
cord-256187-ofp7tupv	311	7	are	be	VBP
cord-256187-ofp7tupv	311	8	ubiquitously	ubiquitously	RB
cord-256187-ofp7tupv	311	9	expressed	express	VBN
cord-256187-ofp7tupv	311	10	in	in	IN
cord-256187-ofp7tupv	311	11	human	human	JJ
cord-256187-ofp7tupv	311	12	cells	cell	NNS
cord-256187-ofp7tupv	311	13	and	and	CC
cord-256187-ofp7tupv	311	14	tissues	tissue	NNS
cord-256187-ofp7tupv	311	15	upon	upon	IN
cord-256187-ofp7tupv	311	16	exposure	exposure	NN
cord-256187-ofp7tupv	311	17	to	to	IN
cord-256187-ofp7tupv	311	18	type	type	NN
cord-256187-ofp7tupv	311	19	I	-PRON-	PRP
cord-256187-ofp7tupv	311	20	(	(	-LRB-
cord-256187-ofp7tupv	311	21	a	a	LS
cord-256187-ofp7tupv	311	22	)	)	-RRB-
cord-256187-ofp7tupv	311	23	and	and	CC
cord-256187-ofp7tupv	312	1	type	type	NNP
cord-256187-ofp7tupv	312	2	II	II	NNP
cord-256187-ofp7tupv	312	3	(	(	-LRB-
cord-256187-ofp7tupv	312	4	c	c	NN
cord-256187-ofp7tupv	312	5	)	)	-RRB-
cord-256187-ofp7tupv	312	6	IFN	IFN	NNP
cord-256187-ofp7tupv	312	7	,	,	,
cord-256187-ofp7tupv	312	8	and	and	CC
cord-256187-ofp7tupv	312	9	homologous	homologous	JJ
cord-256187-ofp7tupv	312	10	proteins	protein	NNS
cord-256187-ofp7tupv	312	11	are	be	VBP
cord-256187-ofp7tupv	312	12	present	present	JJ
cord-256187-ofp7tupv	312	13	in	in	IN
cord-256187-ofp7tupv	312	14	many	many	JJ
cord-256187-ofp7tupv	312	15	vertebrates	vertebrate	NNS
cord-256187-ofp7tupv	312	16	(	(	-LRB-
cord-256187-ofp7tupv	312	17	Siegrist	Siegrist	NNP
cord-256187-ofp7tupv	312	18	et	et	FW
cord-256187-ofp7tupv	312	19	al	al	NNP
cord-256187-ofp7tupv	312	20	.	.	NNP
cord-256187-ofp7tupv	312	21	,	,	,
cord-256187-ofp7tupv	312	22	2011	2011	CD
cord-256187-ofp7tupv	312	23	)	)	-RRB-
cord-256187-ofp7tupv	312	24	.	.	.
cord-256187-ofp7tupv	313	1	IFITM	ifitm	NN
cord-256187-ofp7tupv	313	2	proteins	protein	NNS
cord-256187-ofp7tupv	313	3	were	be	VBD
cord-256187-ofp7tupv	313	4	shown	show	VBN
cord-256187-ofp7tupv	313	5	to	to	TO
cord-256187-ofp7tupv	313	6	play	play	VB
cord-256187-ofp7tupv	313	7	a	a	DT
cord-256187-ofp7tupv	313	8	role	role	NN
cord-256187-ofp7tupv	313	9	in	in	IN
cord-256187-ofp7tupv	313	10	early	early	JJ
cord-256187-ofp7tupv	313	11	development	development	NN
cord-256187-ofp7tupv	313	12	,	,	,
cord-256187-ofp7tupv	313	13	cell	cell	NN
cord-256187-ofp7tupv	313	14	adhesion	adhesion	NN
cord-256187-ofp7tupv	313	15	and	and	CC
cord-256187-ofp7tupv	313	16	control	control	NN
cord-256187-ofp7tupv	313	17	of	of	IN
cord-256187-ofp7tupv	313	18	cell	cell	NN
cord-256187-ofp7tupv	313	19	growth	growth	NN
cord-256187-ofp7tupv	313	20	(	(	-LRB-
cord-256187-ofp7tupv	313	21	Siegrist	Siegrist	NNP
cord-256187-ofp7tupv	313	22	et	et	FW
cord-256187-ofp7tupv	313	23	al	al	NNP
cord-256187-ofp7tupv	313	24	.	.	NNP
cord-256187-ofp7tupv	313	25	,	,	,
cord-256187-ofp7tupv	313	26	2011	2011	CD
cord-256187-ofp7tupv	313	27	)	)	-RRB-
cord-256187-ofp7tupv	313	28	.	.	.
cord-256187-ofp7tupv	314	1	Their	-PRON-	PRP$
cord-256187-ofp7tupv	314	2	antiviral	antiviral	JJ
cord-256187-ofp7tupv	314	3	activity	activity	NN
cord-256187-ofp7tupv	314	4	was	be	VBD
cord-256187-ofp7tupv	314	5	discovered	discover	VBN
cord-256187-ofp7tupv	314	6	in	in	IN
cord-256187-ofp7tupv	314	7	a	a	DT
cord-256187-ofp7tupv	314	8	siRNA	siRNA	NNP
cord-256187-ofp7tupv	314	9	screen	screen	NN
cord-256187-ofp7tupv	314	10	designed	design	VBN
cord-256187-ofp7tupv	314	11	to	to	TO
cord-256187-ofp7tupv	314	12	identify	identify	VB
cord-256187-ofp7tupv	314	13	host	host	NN
cord-256187-ofp7tupv	314	14	cell	cell	NN
cord-256187-ofp7tupv	314	15	factors	factor	NNS
cord-256187-ofp7tupv	314	16	modulating	modulate	VBG
cord-256187-ofp7tupv	314	17	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	314	18	infection	infection	NN
cord-256187-ofp7tupv	315	1	(	(	-LRB-
cord-256187-ofp7tupv	315	2	Brass	Brass	NNP
cord-256187-ofp7tupv	315	3	et	et	FW
cord-256187-ofp7tupv	315	4	al	al	NNP
cord-256187-ofp7tupv	315	5	.	.	NNP
cord-256187-ofp7tupv	315	6	,	,	,
cord-256187-ofp7tupv	315	7	2009	2009	CD
cord-256187-ofp7tupv	315	8	)	)	-RRB-
cord-256187-ofp7tupv	315	9	.	.	.
cord-256187-ofp7tupv	316	1	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	316	2	was	be	VBD
cord-256187-ofp7tupv	316	3	identified	identify	VBN
cord-256187-ofp7tupv	316	4	as	as	IN
cord-256187-ofp7tupv	316	5	a	a	DT
cord-256187-ofp7tupv	316	6	potent	potent	JJ
cord-256187-ofp7tupv	316	7	inhibitor	inhibitor	NN
cord-256187-ofp7tupv	316	8	of	of	IN
cord-256187-ofp7tupv	316	9	host	host	NN
cord-256187-ofp7tupv	316	10	cell	cell	NN
cord-256187-ofp7tupv	316	11	entry	entry	NN
cord-256187-ofp7tupv	316	12	of	of	IN
cord-256187-ofp7tupv	316	13	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	316	14	and	and	CC
cord-256187-ofp7tupv	316	15	members	member	NNS
cord-256187-ofp7tupv	316	16	of	of	IN
cord-256187-ofp7tupv	316	17	the	the	DT
cord-256187-ofp7tupv	316	18	family	family	NN
cord-256187-ofp7tupv	316	19	Flaviviridae	Flaviviridae	NNP
cord-256187-ofp7tupv	316	20	,	,	,
cord-256187-ofp7tupv	316	21	West	West	NNP
cord-256187-ofp7tupv	316	22	Nile	Nile	NNP
cord-256187-ofp7tupv	316	23	virus	virus	NN
cord-256187-ofp7tupv	316	24	and	and	CC
cord-256187-ofp7tupv	316	25	Dengue	dengue	NN
cord-256187-ofp7tupv	316	26	virus	virus	NN
cord-256187-ofp7tupv	316	27	serotype	serotype	NN
cord-256187-ofp7tupv	316	28	2	2	CD
cord-256187-ofp7tupv	316	29	,	,	,
cord-256187-ofp7tupv	316	30	but	but	CC
cord-256187-ofp7tupv	316	31	not	not	RB
cord-256187-ofp7tupv	316	32	hepatitis	hepatitis	NN
cord-256187-ofp7tupv	316	33	C	C	NNP
cord-256187-ofp7tupv	316	34	Virus	Virus	NNP
cord-256187-ofp7tupv	316	35	(	(	-LRB-
cord-256187-ofp7tupv	316	36	Brass	Brass	NNP
cord-256187-ofp7tupv	316	37	et	et	FW
cord-256187-ofp7tupv	316	38	al	al	NNP
cord-256187-ofp7tupv	316	39	.	.	NNP
cord-256187-ofp7tupv	316	40	,	,	,
cord-256187-ofp7tupv	316	41	2009	2009	CD
cord-256187-ofp7tupv	316	42	;	;	:
cord-256187-ofp7tupv	316	43	Jiang	Jiang	NNP
cord-256187-ofp7tupv	316	44	et	et	FW
cord-256187-ofp7tupv	316	45	al	al	NNP
cord-256187-ofp7tupv	316	46	.	.	NNP
cord-256187-ofp7tupv	316	47	,	,	,
cord-256187-ofp7tupv	316	48	2010	2010	CD
cord-256187-ofp7tupv	316	49	)	)	-RRB-
cord-256187-ofp7tupv	316	50	,	,	,
cord-256187-ofp7tupv	316	51	and	and	CC
cord-256187-ofp7tupv	316	52	the	the	DT
cord-256187-ofp7tupv	316	53	induction	induction	NN
cord-256187-ofp7tupv	316	54	of	of	IN
cord-256187-ofp7tupv	316	55	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	316	56	expression	expression	NN
cord-256187-ofp7tupv	316	57	was	be	VBD
cord-256187-ofp7tupv	316	58	shown	show	VBN
cord-256187-ofp7tupv	316	59	to	to	TO
cord-256187-ofp7tupv	316	60	be	be	VB
cord-256187-ofp7tupv	316	61	largely	largely	RB
cord-256187-ofp7tupv	316	62	responsible	responsible	JJ
cord-256187-ofp7tupv	316	63	for	for	IN
cord-256187-ofp7tupv	316	64	the	the	DT
cord-256187-ofp7tupv	316	65	blockade	blockade	NN
cord-256187-ofp7tupv	316	66	to	to	IN
cord-256187-ofp7tupv	316	67	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	316	68	entry	entry	NN
cord-256187-ofp7tupv	316	69	imposed	impose	VBN
cord-256187-ofp7tupv	316	70	by	by	IN
cord-256187-ofp7tupv	316	71	treatment	treatment	NN
cord-256187-ofp7tupv	316	72	of	of	IN
cord-256187-ofp7tupv	316	73	target	target	NN
cord-256187-ofp7tupv	316	74	cells	cell	NNS
cord-256187-ofp7tupv	316	75	with	with	IN
cord-256187-ofp7tupv	316	76	IFNs	ifn	NNS
cord-256187-ofp7tupv	316	77	(	(	-LRB-
cord-256187-ofp7tupv	316	78	Brass	Brass	NNP
cord-256187-ofp7tupv	316	79	et	et	FW
cord-256187-ofp7tupv	316	80	al	al	NNP
cord-256187-ofp7tupv	316	81	.	.	NNP
cord-256187-ofp7tupv	316	82	,	,	,
cord-256187-ofp7tupv	316	83	2009	2009	CD
cord-256187-ofp7tupv	316	84	)	)	-RRB-
cord-256187-ofp7tupv	316	85	.	.	.
cord-256187-ofp7tupv	317	1	IFITM1	IFITM1	NNP
cord-256187-ofp7tupv	317	2	and	and	CC
cord-256187-ofp7tupv	317	3	2	2	CD
cord-256187-ofp7tupv	317	4	were	be	VBD
cord-256187-ofp7tupv	317	5	also	also	RB
cord-256187-ofp7tupv	317	6	shown	show	VBN
cord-256187-ofp7tupv	317	7	to	to	TO
cord-256187-ofp7tupv	317	8	restrict	restrict	VB
cord-256187-ofp7tupv	317	9	viral	viral	JJ
cord-256187-ofp7tupv	317	10	infection	infection	NN
cord-256187-ofp7tupv	317	11	although	although	IN
cord-256187-ofp7tupv	317	12	to	to	IN
cord-256187-ofp7tupv	317	13	a	a	DT
cord-256187-ofp7tupv	317	14	lower	low	JJR
cord-256187-ofp7tupv	317	15	extent	extent	NN
cord-256187-ofp7tupv	317	16	,	,	,
cord-256187-ofp7tupv	317	17	and	and	CC
cord-256187-ofp7tupv	317	18	the	the	DT
cord-256187-ofp7tupv	317	19	antiviral	antiviral	JJ
cord-256187-ofp7tupv	317	20	activity	activity	NN
cord-256187-ofp7tupv	317	21	of	of	IN
cord-256187-ofp7tupv	317	22	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	317	23	was	be	VBD
cord-256187-ofp7tupv	317	24	conserved	conserve	VBN
cord-256187-ofp7tupv	317	25	between	between	IN
cord-256187-ofp7tupv	317	26	human	human	JJ
cord-256187-ofp7tupv	317	27	proteins	protein	NNS
cord-256187-ofp7tupv	317	28	and	and	CC
cord-256187-ofp7tupv	317	29	murine	murine	JJ
cord-256187-ofp7tupv	317	30	orthologues	orthologue	NNS
cord-256187-ofp7tupv	318	1	(	(	-LRB-
cord-256187-ofp7tupv	318	2	Brass	Brass	NNP
cord-256187-ofp7tupv	318	3	et	et	FW
cord-256187-ofp7tupv	318	4	al	al	NNP
cord-256187-ofp7tupv	318	5	.	.	NNP
cord-256187-ofp7tupv	318	6	,	,	,
cord-256187-ofp7tupv	318	7	2009	2009	CD
cord-256187-ofp7tupv	318	8	)	)	-RRB-
cord-256187-ofp7tupv	318	9	.	.	.
cord-256187-ofp7tupv	319	1	Thus	thus	RB
cord-256187-ofp7tupv	319	2	,	,	,
cord-256187-ofp7tupv	319	3	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	319	4	are	be	VBP
cord-256187-ofp7tupv	319	5	novel	novel	JJ
cord-256187-ofp7tupv	319	6	IFN	IFN	NNP
cord-256187-ofp7tupv	319	7	-	-	HYPH
cord-256187-ofp7tupv	319	8	induced	induce	VBN
cord-256187-ofp7tupv	319	9	antiviral	antiviral	JJ
cord-256187-ofp7tupv	319	10	effector	effector	NN
cord-256187-ofp7tupv	319	11	proteins	protein	NNS
cord-256187-ofp7tupv	319	12	,	,	,
cord-256187-ofp7tupv	319	13	which	which	WDT
cord-256187-ofp7tupv	319	14	could	could	MD
cord-256187-ofp7tupv	319	15	modulate	modulate	VB
cord-256187-ofp7tupv	319	16	viral	viral	JJ
cord-256187-ofp7tupv	319	17	spread	spread	NN
cord-256187-ofp7tupv	319	18	in	in	IN
cord-256187-ofp7tupv	319	19	humans	human	NNS
cord-256187-ofp7tupv	319	20	and	and	CC
cord-256187-ofp7tupv	319	21	animals	animal	NNS
cord-256187-ofp7tupv	319	22	.	.	.
cord-256187-ofp7tupv	320	1	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	320	2	restrict	restrict	VBP
cord-256187-ofp7tupv	320	3	viral	viral	JJ
cord-256187-ofp7tupv	320	4	entry	entry	NN
cord-256187-ofp7tupv	320	5	into	into	IN
cord-256187-ofp7tupv	320	6	host	host	NN
cord-256187-ofp7tupv	320	7	cells	cell	NNS
cord-256187-ofp7tupv	320	8	While	while	IN
cord-256187-ofp7tupv	320	9	antiviral	antiviral	JJ
cord-256187-ofp7tupv	320	10	activity	activity	NN
cord-256187-ofp7tupv	320	11	of	of	IN
cord-256187-ofp7tupv	320	12	IFITMs	IFITMs	NNPS
cord-256187-ofp7tupv	320	13	was	be	VBD
cord-256187-ofp7tupv	320	14	initially	initially	RB
cord-256187-ofp7tupv	320	15	reported	report	VBN
cord-256187-ofp7tupv	320	16	for	for	IN
cord-256187-ofp7tupv	320	17	influenza	influenza	NN
cord-256187-ofp7tupv	320	18	and	and	CC
cord-256187-ofp7tupv	320	19	flaviviruses	flavivirus	NNS
cord-256187-ofp7tupv	320	20	(	(	-LRB-
cord-256187-ofp7tupv	320	21	Brass	Brass	NNP
cord-256187-ofp7tupv	320	22	et	et	FW
cord-256187-ofp7tupv	320	23	al	al	NNP
cord-256187-ofp7tupv	320	24	.	.	NNP
cord-256187-ofp7tupv	320	25	,	,	,
cord-256187-ofp7tupv	320	26	2009	2009	CD
cord-256187-ofp7tupv	320	27	;	;	.
cord-256187-ofp7tupv	321	1	Jiang	Jiang	NNP
cord-256187-ofp7tupv	321	2	et	et	NNP
cord-256187-ofp7tupv	321	3	al	al	NNP
cord-256187-ofp7tupv	321	4	.	.	NNP
cord-256187-ofp7tupv	321	5	,	,	,
cord-256187-ofp7tupv	321	6	2010	2010	CD
cord-256187-ofp7tupv	321	7	)	)	-RRB-
cord-256187-ofp7tupv	321	8	,	,	,
cord-256187-ofp7tupv	321	9	subsequent	subsequent	JJ
cord-256187-ofp7tupv	321	10	studies	study	NNS
cord-256187-ofp7tupv	321	11	showed	show	VBD
cord-256187-ofp7tupv	321	12	that	that	IN
cord-256187-ofp7tupv	321	13	IFITMs	ifitms	RB
cord-256187-ofp7tupv	321	14	inhibit	inhibit	VBP
cord-256187-ofp7tupv	321	15	entry	entry	NN
cord-256187-ofp7tupv	321	16	of	of	IN
cord-256187-ofp7tupv	321	17	additional	additional	JJ
cord-256187-ofp7tupv	321	18	enveloped	envelop	VBN
cord-256187-ofp7tupv	321	19	viruses	virus	NNS
cord-256187-ofp7tupv	321	20	such	such	JJ
cord-256187-ofp7tupv	321	21	as	as	IN
cord-256187-ofp7tupv	321	22	vesicular	vesicular	JJ
cord-256187-ofp7tupv	321	23	stomatitis	stomatitis	NN
cord-256187-ofp7tupv	321	24	Indiana	Indiana	NNP
cord-256187-ofp7tupv	321	25	virus	virus	NN
cord-256187-ofp7tupv	321	26	(	(	-LRB-
cord-256187-ofp7tupv	321	27	VSIV	VSIV	NNP
cord-256187-ofp7tupv	321	28	)	)	-RRB-
cord-256187-ofp7tupv	321	29	,	,	,
cord-256187-ofp7tupv	321	30	severe	severe	JJ
cord-256187-ofp7tupv	321	31	acute	acute	JJ
cord-256187-ofp7tupv	321	32	respiratory	respiratory	JJ
cord-256187-ofp7tupv	321	33	syndrome	syndrome	NN
cord-256187-ofp7tupv	321	34	coronavirus	coronavirus	NN
cord-256187-ofp7tupv	321	35	(	(	-LRB-
cord-256187-ofp7tupv	321	36	SARS	SARS	NNP
cord-256187-ofp7tupv	321	37	-	-	HYPH
cord-256187-ofp7tupv	321	38	CoV	CoV	NNP
cord-256187-ofp7tupv	321	39	)	)	-RRB-
cord-256187-ofp7tupv	321	40	and	and	CC
cord-256187-ofp7tupv	321	41	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	321	42	Huang	Huang	NNP
cord-256187-ofp7tupv	321	43	et	et	FW
cord-256187-ofp7tupv	321	44	al	al	NNP
cord-256187-ofp7tupv	321	45	.	.	NNP
cord-256187-ofp7tupv	321	46	,	,	,
cord-256187-ofp7tupv	321	47	2011	2011	CD
cord-256187-ofp7tupv	321	48	)	)	-RRB-
cord-256187-ofp7tupv	321	49	,	,	,
cord-256187-ofp7tupv	321	50	which	which	WDT
cord-256187-ofp7tupv	321	51	,	,	,
cord-256187-ofp7tupv	321	52	very	very	RB
cord-256187-ofp7tupv	321	53	much	much	RB
cord-256187-ofp7tupv	321	54	like	like	IN
cord-256187-ofp7tupv	321	55	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	321	56	and	and	CC
cord-256187-ofp7tupv	321	57	flaviviruses	flavivirus	NNS
cord-256187-ofp7tupv	321	58	,	,	,
cord-256187-ofp7tupv	321	59	depend	depend	VBP
cord-256187-ofp7tupv	321	60	on	on	IN
cord-256187-ofp7tupv	321	61	endo-/	endo-/	CD
cord-256187-ofp7tupv	321	62	lysosomal	lysosomal	JJ
cord-256187-ofp7tupv	321	63	acidic	acidic	JJ
cord-256187-ofp7tupv	321	64	pH	ph	NN
cord-256187-ofp7tupv	321	65	for	for	IN
cord-256187-ofp7tupv	321	66	host	host	NN
cord-256187-ofp7tupv	321	67	cell	cell	NN
cord-256187-ofp7tupv	321	68	entry	entry	NN
cord-256187-ofp7tupv	321	69	.	.	.
cord-256187-ofp7tupv	322	1	Inhibition	inhibition	NN
cord-256187-ofp7tupv	322	2	of	of	IN
cord-256187-ofp7tupv	322	3	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	322	4	and	and	CC
cord-256187-ofp7tupv	322	5	SARS	SARS	NNP
cord-256187-ofp7tupv	322	6	-	-	HYPH
cord-256187-ofp7tupv	322	7	CoV	CoV	NNP
cord-256187-ofp7tupv	322	8	was	be	VBD
cord-256187-ofp7tupv	322	9	demonstrated	demonstrate	VBN
cord-256187-ofp7tupv	322	10	employing	employ	VBG
cord-256187-ofp7tupv	322	11	lentiviral	lentiviral	NNP
cord-256187-ofp7tupv	322	12	vectors	vector	NNS
cord-256187-ofp7tupv	322	13	pseudotyped	pseudotyped	NNP
cord-256187-ofp7tupv	322	14	with	with	IN
cord-256187-ofp7tupv	322	15	the	the	DT
cord-256187-ofp7tupv	322	16	respective	respective	JJ
cord-256187-ofp7tupv	322	17	viral	viral	JJ
cord-256187-ofp7tupv	322	18	GPs	gps	NNS
cord-256187-ofp7tupv	322	19	and	and	CC
cord-256187-ofp7tupv	322	20	with	with	IN
cord-256187-ofp7tupv	322	21	replication	replication	NN
cord-256187-ofp7tupv	322	22	competent	competent	JJ
cord-256187-ofp7tupv	322	23	virus	virus	NN
cord-256187-ofp7tupv	322	24	(	(	-LRB-
cord-256187-ofp7tupv	322	25	Huang	Huang	NNP
cord-256187-ofp7tupv	322	26	et	et	NNP
cord-256187-ofp7tupv	322	27	al	al	NNP
cord-256187-ofp7tupv	322	28	.	.	NNP
cord-256187-ofp7tupv	322	29	,	,	,
cord-256187-ofp7tupv	322	30	2011	2011	CD
cord-256187-ofp7tupv	322	31	)	)	-RRB-
cord-256187-ofp7tupv	322	32	,	,	,
cord-256187-ofp7tupv	322	33	but	but	CC
cord-256187-ofp7tupv	322	34	the	the	DT
cord-256187-ofp7tupv	322	35	inhibitory	inhibitory	JJ
cord-256187-ofp7tupv	322	36	efficiency	efficiency	NN
cord-256187-ofp7tupv	322	37	was	be	VBD
cord-256187-ofp7tupv	322	38	modest	modest	JJ
cord-256187-ofp7tupv	322	39	.	.	.
cord-256187-ofp7tupv	323	1	In	in	IN
cord-256187-ofp7tupv	323	2	contrast	contrast	NN
cord-256187-ofp7tupv	323	3	to	to	IN
cord-256187-ofp7tupv	323	4	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	323	5	,	,	,
cord-256187-ofp7tupv	323	6	IFITM1	IFITM1	NNP
cord-256187-ofp7tupv	323	7	showed	show	VBD
cord-256187-ofp7tupv	323	8	the	the	DT
cord-256187-ofp7tupv	323	9	most	most	RBS
cord-256187-ofp7tupv	323	10	prominent	prominent	JJ
cord-256187-ofp7tupv	323	11	antiviral	antiviral	JJ
cord-256187-ofp7tupv	323	12	effects	effect	NNS
cord-256187-ofp7tupv	323	13	against	against	IN
cord-256187-ofp7tupv	323	14	replication	replication	NN
cord-256187-ofp7tupv	323	15	competent	competent	JJ
cord-256187-ofp7tupv	323	16	EBOV	EBOV	NNP
cord-256187-ofp7tupv	323	17	and	and	CC
cord-256187-ofp7tupv	323	18	MARV	MARV	NNP
cord-256187-ofp7tupv	323	19	,	,	,
cord-256187-ofp7tupv	323	20	while	while	IN
cord-256187-ofp7tupv	323	21	inhibition	inhibition	NN
cord-256187-ofp7tupv	323	22	by	by	IN
cord-256187-ofp7tupv	323	23	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	323	24	was	be	VBD
cord-256187-ofp7tupv	323	25	less	less	RBR
cord-256187-ofp7tupv	323	26	efficient	efficient	JJ
cord-256187-ofp7tupv	324	1	(	(	-LRB-
cord-256187-ofp7tupv	324	2	Huang	Huang	NNP
cord-256187-ofp7tupv	324	3	et	et	NNP
cord-256187-ofp7tupv	324	4	al	al	NNP
cord-256187-ofp7tupv	324	5	.	.	NNP
cord-256187-ofp7tupv	324	6	,	,	,
cord-256187-ofp7tupv	324	7	2011	2011	CD
cord-256187-ofp7tupv	324	8	)	)	-RRB-
cord-256187-ofp7tupv	324	9	.	.	.
cord-256187-ofp7tupv	325	1	Entry	entry	NN
cord-256187-ofp7tupv	325	2	of	of	IN
cord-256187-ofp7tupv	325	3	MARV	MARV	NNP
cord-256187-ofp7tupv	325	4	and	and	CC
cord-256187-ofp7tupv	325	5	EBOV	EBOV	NNP
cord-256187-ofp7tupv	325	6	was	be	VBD
cord-256187-ofp7tupv	325	7	reduced	reduce	VBN
cord-256187-ofp7tupv	325	8	by	by	IN
cord-256187-ofp7tupv	325	9	the	the	DT
cord-256187-ofp7tupv	325	10	expression	expression	NN
cord-256187-ofp7tupv	325	11	of	of	IN
cord-256187-ofp7tupv	325	12	several	several	JJ
cord-256187-ofp7tupv	325	13	IFITM	IFITM	NNP
cord-256187-ofp7tupv	325	14	orthologues	orthologue	NNS
cord-256187-ofp7tupv	325	15	of	of	IN
cord-256187-ofp7tupv	325	16	mouse	mouse	NN
cord-256187-ofp7tupv	325	17	and	and	CC
cord-256187-ofp7tupv	325	18	chicken	chicken	NN
cord-256187-ofp7tupv	325	19	,	,	,
cord-256187-ofp7tupv	325	20	although	although	IN
cord-256187-ofp7tupv	325	21	with	with	IN
cord-256187-ofp7tupv	325	22	different	different	JJ
cord-256187-ofp7tupv	325	23	efficacies	efficacy	NNS
cord-256187-ofp7tupv	325	24	compared	compare	VBN
cord-256187-ofp7tupv	325	25	to	to	IN
cord-256187-ofp7tupv	325	26	the	the	DT
cord-256187-ofp7tupv	325	27	human	human	JJ
cord-256187-ofp7tupv	325	28	proteins	protein	NNS
cord-256187-ofp7tupv	325	29	(	(	-LRB-
cord-256187-ofp7tupv	325	30	Huang	Huang	NNP
cord-256187-ofp7tupv	325	31	et	et	NNP
cord-256187-ofp7tupv	325	32	al	al	NNP
cord-256187-ofp7tupv	325	33	.	.	NNP
cord-256187-ofp7tupv	325	34	,	,	,
cord-256187-ofp7tupv	325	35	2011	2011	CD
cord-256187-ofp7tupv	325	36	)	)	-RRB-
cord-256187-ofp7tupv	325	37	.	.	.
cord-256187-ofp7tupv	326	1	Depletion	depletion	NN
cord-256187-ofp7tupv	326	2	of	of	IN
cord-256187-ofp7tupv	326	3	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	326	4	by	by	IN
cord-256187-ofp7tupv	326	5	shRNA	shrna	NN
cord-256187-ofp7tupv	326	6	was	be	VBD
cord-256187-ofp7tupv	326	7	sufficient	sufficient	JJ
cord-256187-ofp7tupv	326	8	to	to	TO
cord-256187-ofp7tupv	326	9	rescue	rescue	VB
cord-256187-ofp7tupv	326	10	entry	entry	NN
cord-256187-ofp7tupv	326	11	of	of	IN
cord-256187-ofp7tupv	326	12	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	326	13	pseudotypes	pseudotype	NNS
cord-256187-ofp7tupv	326	14	,	,	,
cord-256187-ofp7tupv	326	15	whereas	whereas	IN
cord-256187-ofp7tupv	326	16	a	a	DT
cord-256187-ofp7tupv	326	17	knockdown	knockdown	NN
cord-256187-ofp7tupv	326	18	of	of	IN
cord-256187-ofp7tupv	326	19	both	both	DT
cord-256187-ofp7tupv	326	20	,	,	,
cord-256187-ofp7tupv	326	21	IFITM1	IFITM1	NNP
cord-256187-ofp7tupv	326	22	and	and	CC
cord-256187-ofp7tupv	326	23	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	326	24	,	,	,
cord-256187-ofp7tupv	326	25	was	be	VBD
cord-256187-ofp7tupv	326	26	required	require	VBN
cord-256187-ofp7tupv	326	27	to	to	TO
cord-256187-ofp7tupv	326	28	increase	increase	VB
cord-256187-ofp7tupv	326	29	entry	entry	NN
cord-256187-ofp7tupv	326	30	of	of	IN
cord-256187-ofp7tupv	326	31	EBOV	EBOV	NNP
cord-256187-ofp7tupv	326	32	and	and	CC
cord-256187-ofp7tupv	326	33	MARV	MARV	NNP
cord-256187-ofp7tupv	326	34	pseudotypes	pseudotype	NNS
cord-256187-ofp7tupv	327	1	(	(	-LRB-
cord-256187-ofp7tupv	327	2	Huang	Huang	NNP
cord-256187-ofp7tupv	327	3	et	et	NNP
cord-256187-ofp7tupv	327	4	al	al	NNP
cord-256187-ofp7tupv	327	5	.	.	NNP
cord-256187-ofp7tupv	327	6	,	,	,
cord-256187-ofp7tupv	327	7	2011	2011	CD
cord-256187-ofp7tupv	327	8	)	)	-RRB-
cord-256187-ofp7tupv	327	9	.	.	.
cord-256187-ofp7tupv	328	1	Finally	finally	RB
cord-256187-ofp7tupv	328	2	,	,	,
cord-256187-ofp7tupv	328	3	a	a	DT
cord-256187-ofp7tupv	328	4	different	different	JJ
cord-256187-ofp7tupv	328	5	study	study	NN
cord-256187-ofp7tupv	328	6	also	also	RB
cord-256187-ofp7tupv	328	7	detected	detect	VBD
cord-256187-ofp7tupv	328	8	inhibition	inhibition	NN
cord-256187-ofp7tupv	328	9	of	of	IN
cord-256187-ofp7tupv	328	10	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	328	11	infection	infection	NN
cord-256187-ofp7tupv	328	12	(	(	-LRB-
cord-256187-ofp7tupv	328	13	Lu	Lu	NNP
cord-256187-ofp7tupv	328	14	et	et	FW
cord-256187-ofp7tupv	328	15	al	al	NNP
cord-256187-ofp7tupv	328	16	.	.	NNP
cord-256187-ofp7tupv	328	17	,	,	,
cord-256187-ofp7tupv	328	18	2011	2011	CD
cord-256187-ofp7tupv	328	19	)	)	-RRB-
cord-256187-ofp7tupv	328	20	,	,	,
cord-256187-ofp7tupv	328	21	which	which	WDT
cord-256187-ofp7tupv	328	22	does	do	VBZ
cord-256187-ofp7tupv	328	23	not	not	RB
cord-256187-ofp7tupv	328	24	depend	depend	VB
cord-256187-ofp7tupv	328	25	on	on	IN
cord-256187-ofp7tupv	328	26	low	low	JJ
cord-256187-ofp7tupv	328	27	pH	ph	NN
cord-256187-ofp7tupv	328	28	,	,	,
cord-256187-ofp7tupv	328	29	and	and	CC
cord-256187-ofp7tupv	328	30	it	-PRON-	PRP
cord-256187-ofp7tupv	328	31	is	be	VBZ
cord-256187-ofp7tupv	328	32	at	at	IN
cord-256187-ofp7tupv	328	33	present	present	JJ
cord-256187-ofp7tupv	328	34	unclear	unclear	NN
cord-256187-ofp7tupv	328	35	which	which	WDT
cord-256187-ofp7tupv	328	36	structure	structure	NN
cord-256187-ofp7tupv	328	37	or	or	CC
cord-256187-ofp7tupv	328	38	process	process	NN
cord-256187-ofp7tupv	328	39	shared	share	VBN
cord-256187-ofp7tupv	328	40	by	by	IN
cord-256187-ofp7tupv	328	41	the	the	DT
cord-256187-ofp7tupv	328	42	viruses	virus	NNS
cord-256187-ofp7tupv	328	43	listed	list	VBN
cord-256187-ofp7tupv	328	44	above	above	RB
cord-256187-ofp7tupv	328	45	for	for	IN
cord-256187-ofp7tupv	328	46	host	host	NN
cord-256187-ofp7tupv	328	47	cell	cell	NN
cord-256187-ofp7tupv	328	48	entry	entry	NN
cord-256187-ofp7tupv	328	49	is	be	VBZ
cord-256187-ofp7tupv	328	50	targeted	target	VBN
cord-256187-ofp7tupv	328	51	by	by	IN
cord-256187-ofp7tupv	328	52	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	328	53	.	.	.
cord-256187-ofp7tupv	329	1	Determinants	determinant	NNS
cord-256187-ofp7tupv	329	2	of	of	IN
cord-256187-ofp7tupv	329	3	the	the	DT
cord-256187-ofp7tupv	329	4	antiviral	antiviral	JJ
cord-256187-ofp7tupv	329	5	activity	activity	NN
cord-256187-ofp7tupv	329	6	of	of	IN
cord-256187-ofp7tupv	329	7	IFITM	IFITM	NNP
cord-256187-ofp7tupv	329	8	proteins	protein	NNS
cord-256187-ofp7tupv	329	9	Domains	domain	NNS
cord-256187-ofp7tupv	329	10	and	and	CC
cord-256187-ofp7tupv	329	11	modifications	modification	NNS
cord-256187-ofp7tupv	329	12	important	important	JJ
cord-256187-ofp7tupv	329	13	for	for	IN
cord-256187-ofp7tupv	329	14	antiviral	antiviral	JJ
cord-256187-ofp7tupv	329	15	activity	activity	NN
cord-256187-ofp7tupv	329	16	of	of	IN
cord-256187-ofp7tupv	329	17	the	the	DT
cord-256187-ofp7tupv	329	18	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	329	19	have	have	VBP
cord-256187-ofp7tupv	329	20	been	be	VBN
cord-256187-ofp7tupv	329	21	identified	identify	VBN
cord-256187-ofp7tupv	329	22	,	,	,
cord-256187-ofp7tupv	329	23	although	although	IN
cord-256187-ofp7tupv	329	24	most	most	JJS
cord-256187-ofp7tupv	329	25	studies	study	NNS
cord-256187-ofp7tupv	329	26	were	be	VBD
cord-256187-ofp7tupv	329	27	not	not	RB
cord-256187-ofp7tupv	329	28	conducted	conduct	VBN
cord-256187-ofp7tupv	329	29	in	in	IN
cord-256187-ofp7tupv	329	30	the	the	DT
cord-256187-ofp7tupv	329	31	context	context	NN
cord-256187-ofp7tupv	329	32	of	of	IN
cord-256187-ofp7tupv	329	33	filovirus	filovirus	NN
cord-256187-ofp7tupv	329	34	infection	infection	NN
cord-256187-ofp7tupv	329	35	.	.	.
cord-256187-ofp7tupv	330	1	Abrogation	abrogation	NN
cord-256187-ofp7tupv	330	2	of	of	IN
cord-256187-ofp7tupv	330	3	S	s	NN
cord-256187-ofp7tupv	330	4	-	-	HYPH
cord-256187-ofp7tupv	330	5	palmitoylation	palmitoylation	NN
cord-256187-ofp7tupv	330	6	of	of	IN
cord-256187-ofp7tupv	330	7	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	330	8	by	by	IN
cord-256187-ofp7tupv	330	9	mutation	mutation	NN
cord-256187-ofp7tupv	330	10	of	of	IN
cord-256187-ofp7tupv	330	11	crucial	crucial	JJ
cord-256187-ofp7tupv	330	12	cysteine	cysteine	NN
cord-256187-ofp7tupv	330	13	residues	residue	NNS
cord-256187-ofp7tupv	330	14	inhibited	inhibit	VBD
cord-256187-ofp7tupv	330	15	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	330	16	clustering	clustering	NN
cord-256187-ofp7tupv	330	17	in	in	IN
cord-256187-ofp7tupv	330	18	membrane	membrane	NN
cord-256187-ofp7tupv	330	19	compartments	compartment	NNS
cord-256187-ofp7tupv	330	20	as	as	RB
cord-256187-ofp7tupv	330	21	well	well	RB
cord-256187-ofp7tupv	330	22	as	as	IN
cord-256187-ofp7tupv	330	23	the	the	DT
cord-256187-ofp7tupv	330	24	antiviral	antiviral	JJ
cord-256187-ofp7tupv	330	25	activity	activity	NN
cord-256187-ofp7tupv	330	26	of	of	IN
cord-256187-ofp7tupv	330	27	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	330	28	against	against	IN
cord-256187-ofp7tupv	330	29	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	330	30	(	(	-LRB-
cord-256187-ofp7tupv	330	31	Yount	Yount	NNP
cord-256187-ofp7tupv	330	32	et	et	NNP
cord-256187-ofp7tupv	330	33	al	al	NNP
cord-256187-ofp7tupv	330	34	.	.	NNP
cord-256187-ofp7tupv	330	35	,	,	,
cord-256187-ofp7tupv	330	36	2010	2010	CD
cord-256187-ofp7tupv	330	37	)	)	-RRB-
cord-256187-ofp7tupv	330	38	.	.	.
cord-256187-ofp7tupv	331	1	The	the	DT
cord-256187-ofp7tupv	331	2	sites	site	NNS
cord-256187-ofp7tupv	331	3	of	of	IN
cord-256187-ofp7tupv	331	4	S	S	NNP
cord-256187-ofp7tupv	331	5	-	-	HYPH
cord-256187-ofp7tupv	331	6	palmitoylation	palmitoylation	NNP
cord-256187-ofp7tupv	331	7	are	be	VBP
cord-256187-ofp7tupv	331	8	highly	highly	RB
cord-256187-ofp7tupv	331	9	conserved	conserve	VBN
cord-256187-ofp7tupv	331	10	in	in	IN
cord-256187-ofp7tupv	331	11	members	member	NNS
cord-256187-ofp7tupv	331	12	of	of	IN
cord-256187-ofp7tupv	331	13	the	the	DT
cord-256187-ofp7tupv	331	14	IFITM	IFITM	NNP
cord-256187-ofp7tupv	331	15	protein	protein	NN
cord-256187-ofp7tupv	331	16	family	family	NN
cord-256187-ofp7tupv	331	17	,	,	,
cord-256187-ofp7tupv	331	18	suggesting	suggest	VBG
cord-256187-ofp7tupv	331	19	a	a	DT
cord-256187-ofp7tupv	331	20	general	general	JJ
cord-256187-ofp7tupv	331	21	role	role	NN
cord-256187-ofp7tupv	331	22	in	in	IN
cord-256187-ofp7tupv	331	23	the	the	DT
cord-256187-ofp7tupv	331	24	antiviral	antiviral	JJ
cord-256187-ofp7tupv	331	25	activity	activity	NN
cord-256187-ofp7tupv	331	26	.	.	.
cord-256187-ofp7tupv	332	1	In	in	IN
cord-256187-ofp7tupv	332	2	addition	addition	NN
cord-256187-ofp7tupv	332	3	,	,	,
cord-256187-ofp7tupv	332	4	the	the	DT
cord-256187-ofp7tupv	332	5	sequence	sequence	NN
cord-256187-ofp7tupv	332	6	of	of	IN
cord-256187-ofp7tupv	332	7	the	the	DT
cord-256187-ofp7tupv	332	8	N	n	CD
cord-256187-ofp7tupv	332	9	-	-	HYPH
cord-256187-ofp7tupv	332	10	terminus	terminus	NN
cord-256187-ofp7tupv	332	11	is	be	VBZ
cord-256187-ofp7tupv	332	12	distinct	distinct	JJ
cord-256187-ofp7tupv	332	13	for	for	IN
cord-256187-ofp7tupv	332	14	the	the	DT
cord-256187-ofp7tupv	332	15	different	different	JJ
cord-256187-ofp7tupv	332	16	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	332	17	as	as	IN
cord-256187-ofp7tupv	332	18	IFITM1	ifitm1	NN
cord-256187-ofp7tupv	332	19	is	be	VBZ
cord-256187-ofp7tupv	332	20	lacking	lack	VBG
cord-256187-ofp7tupv	332	21	an	an	DT
cord-256187-ofp7tupv	332	22	N	n	CD
cord-256187-ofp7tupv	332	23	-	-	HYPH
cord-256187-ofp7tupv	332	24	terminal	terminal	NN
cord-256187-ofp7tupv	332	25	amino	amino	NN
cord-256187-ofp7tupv	332	26	acid	acid	NN
cord-256187-ofp7tupv	332	27	stretch	stretch	NN
cord-256187-ofp7tupv	332	28	present	present	JJ
cord-256187-ofp7tupv	332	29	in	in	IN
cord-256187-ofp7tupv	332	30	IFITM2	IFITM2	NNP
cord-256187-ofp7tupv	333	1	and	and	CC
cord-256187-ofp7tupv	333	2	3	3	CD
cord-256187-ofp7tupv	333	3	.	.	.
cord-256187-ofp7tupv	334	1	Part	part	NN
cord-256187-ofp7tupv	334	2	of	of	IN
cord-256187-ofp7tupv	334	3	the	the	DT
cord-256187-ofp7tupv	334	4	N	n	CD
cord-256187-ofp7tupv	334	5	-	-	HYPH
cord-256187-ofp7tupv	334	6	terminus	terminus	NN
cord-256187-ofp7tupv	334	7	might	may	MD
cord-256187-ofp7tupv	334	8	be	be	VB
cord-256187-ofp7tupv	334	9	crucial	crucial	JJ
cord-256187-ofp7tupv	334	10	for	for	IN
cord-256187-ofp7tupv	334	11	their	-PRON-	PRP$
cord-256187-ofp7tupv	334	12	different	different	JJ
cord-256187-ofp7tupv	334	13	antiviral	antiviral	JJ
cord-256187-ofp7tupv	334	14	activity	activity	NN
cord-256187-ofp7tupv	334	15	(	(	-LRB-
cord-256187-ofp7tupv	334	16	Siegrist	Siegrist	NNP
cord-256187-ofp7tupv	334	17	et	et	FW
cord-256187-ofp7tupv	334	18	al	al	NNP
cord-256187-ofp7tupv	334	19	.	.	NNP
cord-256187-ofp7tupv	334	20	,	,	,
cord-256187-ofp7tupv	334	21	2011	2011	CD
cord-256187-ofp7tupv	334	22	)	)	-RRB-
cord-256187-ofp7tupv	334	23	.	.	.
cord-256187-ofp7tupv	335	1	Indeed	indeed	RB
cord-256187-ofp7tupv	335	2	,	,	,
cord-256187-ofp7tupv	335	3	the	the	DT
cord-256187-ofp7tupv	335	4	characterization	characterization	NN
cord-256187-ofp7tupv	335	5	of	of	IN
cord-256187-ofp7tupv	335	6	IFITM1	IFITM1	NNP
cord-256187-ofp7tupv	335	7	/	/	SYM
cord-256187-ofp7tupv	335	8	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	335	9	chimeras	chimera	NNS
cord-256187-ofp7tupv	335	10	revealed	reveal	VBD
cord-256187-ofp7tupv	335	11	that	that	IN
cord-256187-ofp7tupv	335	12	sequences	sequence	NNS
cord-256187-ofp7tupv	335	13	within	within	IN
cord-256187-ofp7tupv	335	14	the	the	DT
cord-256187-ofp7tupv	335	15	N	N	NNP
cord-256187-ofp7tupv	335	16	-	-	HYPH
cord-256187-ofp7tupv	335	17	and	and	CC
cord-256187-ofp7tupv	335	18	C	c	NN
cord-256187-ofp7tupv	335	19	-	-	HYPH
cord-256187-ofp7tupv	335	20	terminus	terminus	NN
cord-256187-ofp7tupv	335	21	of	of	IN
cord-256187-ofp7tupv	335	22	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	335	23	are	be	VBP
cord-256187-ofp7tupv	335	24	important	important	JJ
cord-256187-ofp7tupv	335	25	for	for	IN
cord-256187-ofp7tupv	335	26	antiviral	antiviral	JJ
cord-256187-ofp7tupv	335	27	activity	activity	NN
cord-256187-ofp7tupv	335	28	against	against	IN
cord-256187-ofp7tupv	335	29	VSIV	VSIV	NNP
cord-256187-ofp7tupv	335	30	.	.	.
cord-256187-ofp7tupv	336	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	336	2	,	,	,
cord-256187-ofp7tupv	336	3	Lu	Lu	NNP
cord-256187-ofp7tupv	336	4	et	et	FW
cord-256187-ofp7tupv	336	5	al	al	NNP
cord-256187-ofp7tupv	336	6	.	.	.
cord-256187-ofp7tupv	337	1	(	(	-LRB-
cord-256187-ofp7tupv	337	2	2011	2011	CD
cord-256187-ofp7tupv	337	3	)	)	-RRB-
cord-256187-ofp7tupv	337	4	could	could	MD
cord-256187-ofp7tupv	337	5	show	show	VB
cord-256187-ofp7tupv	337	6	that	that	IN
cord-256187-ofp7tupv	337	7	only	only	RB
cord-256187-ofp7tupv	337	8	IFITM-2	IFITM-2	NNS
cord-256187-ofp7tupv	337	9	and	and	CC
cord-256187-ofp7tupv	337	10	IFITM-3	IFITM-3	NNP
cord-256187-ofp7tupv	337	11	inhibit	inhibit	VBP
cord-256187-ofp7tupv	337	12	the	the	DT
cord-256187-ofp7tupv	337	13	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	337	14	life	life	NN
cord-256187-ofp7tupv	337	15	cycle	cycle	NN
cord-256187-ofp7tupv	337	16	at	at	IN
cord-256187-ofp7tupv	337	17	the	the	DT
cord-256187-ofp7tupv	337	18	step	step	NN
cord-256187-ofp7tupv	337	19	of	of	IN
cord-256187-ofp7tupv	337	20	viral	viral	JJ
cord-256187-ofp7tupv	337	21	entry	entry	NN
cord-256187-ofp7tupv	337	22	,	,	,
cord-256187-ofp7tupv	337	23	and	and	CC
cord-256187-ofp7tupv	337	24	that	that	DT
cord-256187-ofp7tupv	337	25	deletion	deletion	NN
cord-256187-ofp7tupv	337	26	of	of	IN
cord-256187-ofp7tupv	337	27	the	the	DT
cord-256187-ofp7tupv	337	28	N	n	CD
cord-256187-ofp7tupv	337	29	-	-	HYPH
cord-256187-ofp7tupv	337	30	terminal	terminal	NN
cord-256187-ofp7tupv	337	31	region	region	NN
cord-256187-ofp7tupv	337	32	abrogated	abrogate	VBD
cord-256187-ofp7tupv	337	33	this	this	DT
cord-256187-ofp7tupv	337	34	ability	ability	NN
cord-256187-ofp7tupv	337	35	.	.	.
cord-256187-ofp7tupv	338	1	IFITM1	ifitm1	UH
cord-256187-ofp7tupv	338	2	,	,	,
cord-256187-ofp7tupv	338	3	in	in	IN
cord-256187-ofp7tupv	338	4	contrast	contrast	NN
cord-256187-ofp7tupv	338	5	,	,	,
cord-256187-ofp7tupv	338	6	needs	need	VBZ
cord-256187-ofp7tupv	338	7	an	an	DT
cord-256187-ofp7tupv	338	8	intact	intact	JJ
cord-256187-ofp7tupv	338	9	intracellular	intracellular	JJ
cord-256187-ofp7tupv	338	10	domain	domain	NN
cord-256187-ofp7tupv	338	11	to	to	TO
cord-256187-ofp7tupv	338	12	inhibit	inhibit	VB
cord-256187-ofp7tupv	338	13	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	338	14	replication	replication	NN
cord-256187-ofp7tupv	338	15	,	,	,
cord-256187-ofp7tupv	338	16	whereas	whereas	IN
cord-256187-ofp7tupv	338	17	the	the	DT
cord-256187-ofp7tupv	338	18	N	N	NNP
cord-256187-ofp7tupv	338	19	-	-	HYPH
cord-256187-ofp7tupv	338	20	and	and	CC
cord-256187-ofp7tupv	338	21	C	C	NNP
cord-256187-ofp7tupv	338	22	-	-	HYPH
cord-256187-ofp7tupv	338	23	terminus	terminus	NN
cord-256187-ofp7tupv	338	24	are	be	VBP
cord-256187-ofp7tupv	338	25	dispensable	dispensable	JJ
cord-256187-ofp7tupv	339	1	(	(	-LRB-
cord-256187-ofp7tupv	339	2	Lu	Lu	NNP
cord-256187-ofp7tupv	339	3	et	et	FW
cord-256187-ofp7tupv	339	4	al	al	NNP
cord-256187-ofp7tupv	339	5	.	.	NNP
cord-256187-ofp7tupv	339	6	,	,	,
cord-256187-ofp7tupv	339	7	2011	2011	CD
cord-256187-ofp7tupv	339	8	)	)	-RRB-
cord-256187-ofp7tupv	339	9	.	.	.
cord-256187-ofp7tupv	340	1	What	what	WP
cord-256187-ofp7tupv	340	2	is	be	VBZ
cord-256187-ofp7tupv	340	3	known	know	VBN
cord-256187-ofp7tupv	340	4	about	about	IN
cord-256187-ofp7tupv	340	5	the	the	DT
cord-256187-ofp7tupv	340	6	mechanism	mechanism	NN
cord-256187-ofp7tupv	340	7	underlying	underlie	VBG
cord-256187-ofp7tupv	340	8	IFITM	IFITM	NNP
cord-256187-ofp7tupv	340	9	dependent	dependent	JJ
cord-256187-ofp7tupv	340	10	inhibition	inhibition	NN
cord-256187-ofp7tupv	340	11	of	of	IN
cord-256187-ofp7tupv	340	12	host	host	NN
cord-256187-ofp7tupv	340	13	cell	cell	NN
cord-256187-ofp7tupv	340	14	entry	entry	NN
cord-256187-ofp7tupv	340	15	of	of	IN
cord-256187-ofp7tupv	340	16	EBOV	EBOV	NNP
cord-256187-ofp7tupv	340	17	and	and	CC
cord-256187-ofp7tupv	340	18	other	other	JJ
cord-256187-ofp7tupv	340	19	viruses	virus	NNS
cord-256187-ofp7tupv	340	20	?	?	.
cord-256187-ofp7tupv	341	1	One	one	CD
cord-256187-ofp7tupv	341	2	possibility	possibility	NN
cord-256187-ofp7tupv	341	3	is	be	VBZ
cord-256187-ofp7tupv	341	4	that	that	IN
cord-256187-ofp7tupv	341	5	IFITMs	ifitms	RB
cord-256187-ofp7tupv	341	6	interfere	interfere	VB
cord-256187-ofp7tupv	341	7	with	with	IN
cord-256187-ofp7tupv	341	8	receptor	receptor	NN
cord-256187-ofp7tupv	341	9	expression	expression	NN
cord-256187-ofp7tupv	341	10	.	.	.
cord-256187-ofp7tupv	342	1	However	however	RB
cord-256187-ofp7tupv	342	2	,	,	,
cord-256187-ofp7tupv	342	3	IFITM	IFITM	NNP
cord-256187-ofp7tupv	342	4	proteins	protein	NNS
cord-256187-ofp7tupv	342	5	do	do	VBP
cord-256187-ofp7tupv	342	6	not	not	RB
cord-256187-ofp7tupv	342	7	interfere	interfere	VB
cord-256187-ofp7tupv	342	8	with	with	IN
cord-256187-ofp7tupv	342	9	the	the	DT
cord-256187-ofp7tupv	342	10	level	level	NN
cord-256187-ofp7tupv	342	11	of	of	IN
cord-256187-ofp7tupv	342	12	surface	surface	NN
cord-256187-ofp7tupv	342	13	expression	expression	NN
cord-256187-ofp7tupv	342	14	of	of	IN
cord-256187-ofp7tupv	342	15	sialic	sialic	JJ
cord-256187-ofp7tupv	342	16	acids	acid	NNS
cord-256187-ofp7tupv	342	17	and	and	CC
cord-256187-ofp7tupv	342	18	ACE2	ACE2	NNP
cord-256187-ofp7tupv	342	19	,	,	,
cord-256187-ofp7tupv	342	20	the	the	DT
cord-256187-ofp7tupv	342	21	receptors	receptor	NNS
cord-256187-ofp7tupv	342	22	for	for	IN
cord-256187-ofp7tupv	342	23	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	342	24	and	and	CC
cord-256187-ofp7tupv	342	25	SARS	SARS	NNP
cord-256187-ofp7tupv	342	26	-	-	HYPH
cord-256187-ofp7tupv	342	27	CoV	CoV	NNP
cord-256187-ofp7tupv	342	28	,	,	,
cord-256187-ofp7tupv	342	29	respectively	respectively	RB
cord-256187-ofp7tupv	342	30	(	(	-LRB-
cord-256187-ofp7tupv	342	31	Brass	Brass	NNP
cord-256187-ofp7tupv	342	32	et	et	FW
cord-256187-ofp7tupv	342	33	al	al	NNP
cord-256187-ofp7tupv	342	34	.	.	.
cord-256187-ofp7tupv	343	1	,	,	,
cord-256187-ofp7tupv	343	2	2009	2009	CD
cord-256187-ofp7tupv	343	3	;	;	:
cord-256187-ofp7tupv	343	4	Huang	Huang	NNP
cord-256187-ofp7tupv	343	5	et	et	NNP
cord-256187-ofp7tupv	343	6	al	al	NNP
cord-256187-ofp7tupv	343	7	.	.	NNP
cord-256187-ofp7tupv	343	8	,	,	,
cord-256187-ofp7tupv	343	9	2011	2011	CD
cord-256187-ofp7tupv	343	10	)	)	-RRB-
cord-256187-ofp7tupv	343	11	.	.	.
cord-256187-ofp7tupv	344	1	IFITM	ifitm	NN
cord-256187-ofp7tupv	344	2	expression	expression	NN
cord-256187-ofp7tupv	344	3	is	be	VBZ
cord-256187-ofp7tupv	344	4	compatible	compatible	JJ
cord-256187-ofp7tupv	344	5	with	with	IN
cord-256187-ofp7tupv	344	6	FLUAV	FLUAV	NNP
cord-256187-ofp7tupv	344	7	access	access	NN
cord-256187-ofp7tupv	344	8	to	to	IN
cord-256187-ofp7tupv	344	9	low	low	JJ
cord-256187-ofp7tupv	344	10	pH	pH	NNP
cord-256187-ofp7tupv	344	11	compartments	compartment	NNS
cord-256187-ofp7tupv	344	12	,	,	,
cord-256187-ofp7tupv	344	13	and	and	CC
cord-256187-ofp7tupv	344	14	inhibition	inhibition	NN
cord-256187-ofp7tupv	344	15	of	of	IN
cord-256187-ofp7tupv	344	16	SARS	SARS	NNP
cord-256187-ofp7tupv	344	17	-	-	HYPH
cord-256187-ofp7tupv	344	18	CoV	CoV	NNP
cord-256187-ofp7tupv	344	19	by	by	IN
cord-256187-ofp7tupv	344	20	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	344	21	could	could	MD
cord-256187-ofp7tupv	344	22	be	be	VB
cord-256187-ofp7tupv	344	23	rescued	rescue	VBN
cord-256187-ofp7tupv	344	24	by	by	IN
cord-256187-ofp7tupv	344	25	forcing	force	VBG
cord-256187-ofp7tupv	344	26	the	the	DT
cord-256187-ofp7tupv	344	27	virus	virus	NN
cord-256187-ofp7tupv	344	28	to	to	TO
cord-256187-ofp7tupv	344	29	fuse	fuse	VB
cord-256187-ofp7tupv	344	30	with	with	IN
cord-256187-ofp7tupv	344	31	the	the	DT
cord-256187-ofp7tupv	344	32	plasma	plasma	NN
cord-256187-ofp7tupv	344	33	membrane	membrane	NN
cord-256187-ofp7tupv	344	34	instead	instead	RB
cord-256187-ofp7tupv	344	35	of	of	IN
cord-256187-ofp7tupv	344	36	an	an	DT
cord-256187-ofp7tupv	344	37	internal	internal	JJ
cord-256187-ofp7tupv	344	38	membrane	membrane	NN
cord-256187-ofp7tupv	345	1	(	(	-LRB-
cord-256187-ofp7tupv	345	2	Huang	Huang	NNP
cord-256187-ofp7tupv	345	3	et	et	NNP
cord-256187-ofp7tupv	345	4	al	al	NNP
cord-256187-ofp7tupv	345	5	.	.	NNP
cord-256187-ofp7tupv	345	6	,	,	,
cord-256187-ofp7tupv	345	7	2011	2011	CD
cord-256187-ofp7tupv	345	8	)	)	-RRB-
cord-256187-ofp7tupv	345	9	.	.	.
cord-256187-ofp7tupv	346	1	Thus	thus	RB
cord-256187-ofp7tupv	346	2	,	,	,
cord-256187-ofp7tupv	346	3	viruses	virus	NNS
cord-256187-ofp7tupv	346	4	might	may	MD
cord-256187-ofp7tupv	346	5	reach	reach	VB
cord-256187-ofp7tupv	346	6	internal	internal	JJ
cord-256187-ofp7tupv	346	7	compartments	compartment	NNS
cord-256187-ofp7tupv	346	8	in	in	IN
cord-256187-ofp7tupv	346	9	IFITM	IFITM	NNP
cord-256187-ofp7tupv	346	10	expressing	express	VBG
cord-256187-ofp7tupv	346	11	cells	cell	NNS
cord-256187-ofp7tupv	346	12	in	in	IN
cord-256187-ofp7tupv	346	13	which	which	WDT
cord-256187-ofp7tupv	346	14	fusion	fusion	NN
cord-256187-ofp7tupv	346	15	of	of	IN
cord-256187-ofp7tupv	346	16	viral	viral	JJ
cord-256187-ofp7tupv	346	17	and	and	CC
cord-256187-ofp7tupv	346	18	compartment	compartment	NN
cord-256187-ofp7tupv	346	19	membrane	membrane	NN
cord-256187-ofp7tupv	346	20	could	could	MD
cord-256187-ofp7tupv	346	21	normally	normally	RB
cord-256187-ofp7tupv	346	22	occur	occur	VB
cord-256187-ofp7tupv	346	23	,	,	,
cord-256187-ofp7tupv	346	24	but	but	CC
cord-256187-ofp7tupv	346	25	membrane	membrane	NN
cord-256187-ofp7tupv	346	26	fusion	fusion	NN
cord-256187-ofp7tupv	346	27	might	may	MD
cord-256187-ofp7tupv	346	28	be	be	VB
cord-256187-ofp7tupv	346	29	blocked	block	VBN
cord-256187-ofp7tupv	346	30	by	by	IN
cord-256187-ofp7tupv	346	31	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	346	32	.	.	.
cord-256187-ofp7tupv	347	1	One	one	CD
cord-256187-ofp7tupv	347	2	possibility	possibility	NN
cord-256187-ofp7tupv	347	3	could	could	MD
cord-256187-ofp7tupv	347	4	be	be	VB
cord-256187-ofp7tupv	347	5	that	that	DT
cord-256187-ofp7tupv	347	6	IFITMs	ifitms	RB
cord-256187-ofp7tupv	347	7	interfere	interfere	VB
cord-256187-ofp7tupv	347	8	with	with	IN
cord-256187-ofp7tupv	347	9	the	the	DT
cord-256187-ofp7tupv	347	10	activity	activity	NN
cord-256187-ofp7tupv	347	11	of	of	IN
cord-256187-ofp7tupv	347	12	cathepsins	cathepsin	NNS
cord-256187-ofp7tupv	347	13	,	,	,
cord-256187-ofp7tupv	347	14	pH	ph	NN
cord-256187-ofp7tupv	347	15	-	-	HYPH
cord-256187-ofp7tupv	347	16	dependent	dependent	JJ
cord-256187-ofp7tupv	347	17	endo-/lysosomal	endo-/lysosomal	JJ
cord-256187-ofp7tupv	347	18	proteases	protease	NNS
cord-256187-ofp7tupv	347	19	essential	essential	JJ
cord-256187-ofp7tupv	347	20	for	for	IN
cord-256187-ofp7tupv	347	21	proteolytic	proteolytic	JJ
cord-256187-ofp7tupv	347	22	activation	activation	NN
cord-256187-ofp7tupv	347	23	of	of	IN
cord-256187-ofp7tupv	347	24	SARS	SARS	NNP
cord-256187-ofp7tupv	347	25	-	-	HYPH
cord-256187-ofp7tupv	347	26	CoV	CoV	NNP
cord-256187-ofp7tupv	347	27	and	and	CC
cord-256187-ofp7tupv	347	28	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	347	29	in	in	IN
cord-256187-ofp7tupv	347	30	vitro	vitro	FW
cord-256187-ofp7tupv	348	1	(	(	-LRB-
cord-256187-ofp7tupv	348	2	Chandran	Chandran	NNP
cord-256187-ofp7tupv	348	3	et	et	FW
cord-256187-ofp7tupv	348	4	al	al	NNP
cord-256187-ofp7tupv	348	5	.	.	.
cord-256187-ofp7tupv	349	1	,	,	,
cord-256187-ofp7tupv	349	2	2005	2005	CD
cord-256187-ofp7tupv	349	3	;	;	:
cord-256187-ofp7tupv	349	4	Simmons	Simmons	NNP
cord-256187-ofp7tupv	349	5	et	et	NNP
cord-256187-ofp7tupv	349	6	al	al	NNP
cord-256187-ofp7tupv	349	7	.	.	NNP
cord-256187-ofp7tupv	349	8	,	,	,
cord-256187-ofp7tupv	349	9	2005	2005	CD
cord-256187-ofp7tupv	349	10	)	)	-RRB-
cord-256187-ofp7tupv	349	11	.	.	.
cord-256187-ofp7tupv	350	1	No	no	DT
cord-256187-ofp7tupv	350	2	appreciable	appreciable	JJ
cord-256187-ofp7tupv	350	3	decrease	decrease	NN
cord-256187-ofp7tupv	350	4	of	of	IN
cord-256187-ofp7tupv	350	5	cathepsin	cathepsin	NN
cord-256187-ofp7tupv	350	6	activity	activity	NN
cord-256187-ofp7tupv	350	7	was	be	VBD
cord-256187-ofp7tupv	350	8	observed	observe	VBN
cord-256187-ofp7tupv	350	9	in	in	IN
cord-256187-ofp7tupv	350	10	IFITM	IFITM	NNP
cord-256187-ofp7tupv	350	11	expressing	express	VBG
cord-256187-ofp7tupv	350	12	cells	cell	NNS
cord-256187-ofp7tupv	351	1	(	(	-LRB-
cord-256187-ofp7tupv	351	2	Huang	Huang	NNP
cord-256187-ofp7tupv	351	3	et	et	NNP
cord-256187-ofp7tupv	351	4	al	al	NNP
cord-256187-ofp7tupv	351	5	.	.	NNP
cord-256187-ofp7tupv	351	6	,	,	,
cord-256187-ofp7tupv	351	7	2011	2011	CD
cord-256187-ofp7tupv	351	8	)	)	-RRB-
cord-256187-ofp7tupv	351	9	.	.	.
cord-256187-ofp7tupv	352	1	The	the	DT
cord-256187-ofp7tupv	352	2	endosomal	endosomal	JJ
cord-256187-ofp7tupv	352	3	membrane	membrane	NN
cord-256187-ofp7tupv	352	4	protein	protein	NN
cord-256187-ofp7tupv	352	5	NPC1	NPC1	NNP
cord-256187-ofp7tupv	352	6	has	have	VBZ
cord-256187-ofp7tupv	352	7	recently	recently	RB
cord-256187-ofp7tupv	352	8	been	be	VBN
cord-256187-ofp7tupv	352	9	reported	report	VBN
cord-256187-ofp7tupv	352	10	as	as	IN
cord-256187-ofp7tupv	352	11	an	an	DT
cord-256187-ofp7tupv	352	12	essential	essential	JJ
cord-256187-ofp7tupv	352	13	host	host	NN
cord-256187-ofp7tupv	352	14	cell	cell	NN
cord-256187-ofp7tupv	352	15	factor	factor	NN
cord-256187-ofp7tupv	352	16	for	for	IN
cord-256187-ofp7tupv	352	17	EBOV	EBOV	NNP
cord-256187-ofp7tupv	352	18	entry	entry	NN
cord-256187-ofp7tupv	353	1	(	(	-LRB-
cord-256187-ofp7tupv	353	2	Carette	Carette	NNP
cord-256187-ofp7tupv	353	3	et	et	NNP
cord-256187-ofp7tupv	353	4	al	al	NNP
cord-256187-ofp7tupv	353	5	.	.	NNP
cord-256187-ofp7tupv	353	6	,	,	,
cord-256187-ofp7tupv	353	7	2011	2011	CD
cord-256187-ofp7tupv	354	1	;	;	:
cord-256187-ofp7tupv	354	2	Cô	Cô	NNP
cord-256187-ofp7tupv	354	3	té	té	NNP
cord-256187-ofp7tupv	354	4	et	et	FW
cord-256187-ofp7tupv	354	5	al	al	NNP
cord-256187-ofp7tupv	354	6	.	.	NNP
cord-256187-ofp7tupv	354	7	,	,	,
cord-256187-ofp7tupv	354	8	2011	2011	CD
cord-256187-ofp7tupv	354	9	)	)	-RRB-
cord-256187-ofp7tupv	354	10	.	.	.
cord-256187-ofp7tupv	355	1	According	accord	VBG
cord-256187-ofp7tupv	355	2	to	to	IN
cord-256187-ofp7tupv	355	3	the	the	DT
cord-256187-ofp7tupv	355	4	model	model	NN
cord-256187-ofp7tupv	355	5	of	of	IN
cord-256187-ofp7tupv	355	6	Cô	Cô	NNP
cord-256187-ofp7tupv	355	7	té	té	NNP
cord-256187-ofp7tupv	355	8	et	et	FW
cord-256187-ofp7tupv	355	9	al	al	NNP
cord-256187-ofp7tupv	355	10	.	.	NNP
cord-256187-ofp7tupv	355	11	,	,	,
cord-256187-ofp7tupv	355	12	NPC1	NPC1	NNP
cord-256187-ofp7tupv	355	13	expression	expression	NN
cord-256187-ofp7tupv	355	14	or	or	CC
cord-256187-ofp7tupv	355	15	activity	activity	NN
cord-256187-ofp7tupv	355	16	is	be	VBZ
cord-256187-ofp7tupv	355	17	required	require	VBN
cord-256187-ofp7tupv	355	18	for	for	IN
cord-256187-ofp7tupv	355	19	endosomal	endosomal	NNP
cord-256187-ofp7tupv	355	20	fusion	fusion	NN
cord-256187-ofp7tupv	355	21	after	after	IN
cord-256187-ofp7tupv	355	22	cathepsin	cathepsin	NN
cord-256187-ofp7tupv	355	23	-	-	HYPH
cord-256187-ofp7tupv	355	24	mediated	mediate	VBN
cord-256187-ofp7tupv	355	25	processing	processing	NN
cord-256187-ofp7tupv	355	26	of	of	IN
cord-256187-ofp7tupv	355	27	GP	GP	NNP
cord-256187-ofp7tupv	355	28	1,2	1,2	CD
cord-256187-ofp7tupv	355	29	.	.	.
cord-256187-ofp7tupv	356	1	It	-PRON-	PRP
cord-256187-ofp7tupv	356	2	is	be	VBZ
cord-256187-ofp7tupv	356	3	conceivable	conceivable	JJ
cord-256187-ofp7tupv	356	4	that	that	IN
cord-256187-ofp7tupv	356	5	IFITMs	ifitms	RB
cord-256187-ofp7tupv	356	6	interfere	interfere	VB
cord-256187-ofp7tupv	356	7	with	with	IN
cord-256187-ofp7tupv	356	8	NPC1	NPC1	NNP
cord-256187-ofp7tupv	356	9	expression	expression	NN
cord-256187-ofp7tupv	356	10	or	or	CC
cord-256187-ofp7tupv	356	11	activity	activity	NN
cord-256187-ofp7tupv	356	12	.	.	.
cord-256187-ofp7tupv	357	1	Furthermore	furthermore	RB
cord-256187-ofp7tupv	357	2	,	,	,
cord-256187-ofp7tupv	357	3	it	-PRON-	PRP
cord-256187-ofp7tupv	357	4	is	be	VBZ
cord-256187-ofp7tupv	357	5	possible	possible	JJ
cord-256187-ofp7tupv	357	6	that	that	IN
cord-256187-ofp7tupv	357	7	a	a	DT
cord-256187-ofp7tupv	357	8	step	step	NN
cord-256187-ofp7tupv	357	9	in	in	IN
cord-256187-ofp7tupv	357	10	the	the	DT
cord-256187-ofp7tupv	357	11	filovirus	filovirus	NN
cord-256187-ofp7tupv	357	12	life	life	NN
cord-256187-ofp7tupv	357	13	cycle	cycle	NN
cord-256187-ofp7tupv	357	14	different	different	JJ
cord-256187-ofp7tupv	357	15	from	from	IN
cord-256187-ofp7tupv	357	16	membrane	membrane	NN
cord-256187-ofp7tupv	357	17	fusion	fusion	NN
cord-256187-ofp7tupv	357	18	could	could	MD
cord-256187-ofp7tupv	357	19	be	be	VB
cord-256187-ofp7tupv	357	20	affected	affect	VBN
cord-256187-ofp7tupv	357	21	by	by	IN
cord-256187-ofp7tupv	357	22	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	357	23	,	,	,
cord-256187-ofp7tupv	357	24	as	as	IN
cord-256187-ofp7tupv	357	25	it	-PRON-	PRP
cord-256187-ofp7tupv	357	26	was	be	VBD
cord-256187-ofp7tupv	357	27	reported	report	VBN
cord-256187-ofp7tupv	357	28	that	that	IN
cord-256187-ofp7tupv	357	29	IFITM2	ifitm2	NN
cord-256187-ofp7tupv	357	30	and	and	CC
cord-256187-ofp7tupv	357	31	3	3	CD
cord-256187-ofp7tupv	357	32	inhibit	inhibit	VB
cord-256187-ofp7tupv	357	33	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	357	34	entry	entry	NN
cord-256187-ofp7tupv	357	35	,	,	,
cord-256187-ofp7tupv	357	36	whereas	whereas	IN
cord-256187-ofp7tupv	357	37	IFITM1	ifitm1	NN
cord-256187-ofp7tupv	357	38	acts	act	NNS
cord-256187-ofp7tupv	357	39	later	later	RB
cord-256187-ofp7tupv	357	40	in	in	IN
cord-256187-ofp7tupv	357	41	the	the	DT
cord-256187-ofp7tupv	357	42	viral	viral	JJ
cord-256187-ofp7tupv	357	43	life	life	NN
cord-256187-ofp7tupv	357	44	cycle	cycle	NN
cord-256187-ofp7tupv	357	45	by	by	IN
cord-256187-ofp7tupv	357	46	suppressing	suppress	VBG
cord-256187-ofp7tupv	357	47	Gag	Gag	NNP
cord-256187-ofp7tupv	357	48	translation	translation	NN
cord-256187-ofp7tupv	357	49	(	(	-LRB-
cord-256187-ofp7tupv	357	50	Lu	Lu	NNP
cord-256187-ofp7tupv	357	51	et	et	FW
cord-256187-ofp7tupv	357	52	al	al	NNP
cord-256187-ofp7tupv	357	53	.	.	NNP
cord-256187-ofp7tupv	357	54	,	,	,
cord-256187-ofp7tupv	357	55	2011	2011	CD
cord-256187-ofp7tupv	357	56	)	)	-RRB-
cord-256187-ofp7tupv	357	57	.	.	.
cord-256187-ofp7tupv	358	1	Thus	thus	RB
cord-256187-ofp7tupv	358	2	,	,	,
cord-256187-ofp7tupv	358	3	the	the	DT
cord-256187-ofp7tupv	358	4	mechanisms	mechanism	NNS
cord-256187-ofp7tupv	358	5	underlying	underlie	VBG
cord-256187-ofp7tupv	358	6	inhibition	inhibition	NN
cord-256187-ofp7tupv	358	7	of	of	IN
cord-256187-ofp7tupv	358	8	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	358	9	and	and	CC
cord-256187-ofp7tupv	358	10	other	other	JJ
cord-256187-ofp7tupv	358	11	viruses	virus	NNS
cord-256187-ofp7tupv	358	12	remain	remain	VBP
cord-256187-ofp7tupv	358	13	to	to	TO
cord-256187-ofp7tupv	358	14	be	be	VB
cord-256187-ofp7tupv	358	15	defined	define	VBN
cord-256187-ofp7tupv	358	16	,	,	,
cord-256187-ofp7tupv	358	17	including	include	VBG
cord-256187-ofp7tupv	358	18	the	the	DT
cord-256187-ofp7tupv	358	19	possibility	possibility	NN
cord-256187-ofp7tupv	358	20	that	that	IN
cord-256187-ofp7tupv	358	21	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	358	22	require	require	VBP
cord-256187-ofp7tupv	358	23	cellular	cellular	JJ
cord-256187-ofp7tupv	358	24	cofactors	cofactor	NNS
cord-256187-ofp7tupv	358	25	to	to	TO
cord-256187-ofp7tupv	358	26	exert	exert	VB
cord-256187-ofp7tupv	358	27	their	-PRON-	PRP$
cord-256187-ofp7tupv	358	28	antiviral	antiviral	JJ
cord-256187-ofp7tupv	358	29	effects	effect	NNS
cord-256187-ofp7tupv	358	30	.	.	.
cord-256187-ofp7tupv	359	1	In	in	IN
cord-256187-ofp7tupv	359	2	sum	sum	NN
cord-256187-ofp7tupv	359	3	,	,	,
cord-256187-ofp7tupv	359	4	IFITMs	ifitms	RB
cord-256187-ofp7tupv	359	5	inhibit	inhibit	VBP
cord-256187-ofp7tupv	359	6	filovirus	filovirus	NN
cord-256187-ofp7tupv	359	7	entry	entry	NN
cord-256187-ofp7tupv	359	8	into	into	IN
cord-256187-ofp7tupv	359	9	host	host	NN
cord-256187-ofp7tupv	359	10	cells	cell	NNS
cord-256187-ofp7tupv	359	11	,	,	,
cord-256187-ofp7tupv	359	12	and	and	CC
cord-256187-ofp7tupv	359	13	the	the	DT
cord-256187-ofp7tupv	359	14	level	level	NN
cord-256187-ofp7tupv	359	15	of	of	IN
cord-256187-ofp7tupv	359	16	constitutive	constitutive	JJ
cord-256187-ofp7tupv	359	17	IFITM	IFITM	NNP
cord-256187-ofp7tupv	359	18	expression	expression	NN
cord-256187-ofp7tupv	359	19	might	may	MD
cord-256187-ofp7tupv	359	20	shape	shape	VB
cord-256187-ofp7tupv	359	21	the	the	DT
cord-256187-ofp7tupv	359	22	choice	choice	NN
cord-256187-ofp7tupv	359	23	of	of	IN
cord-256187-ofp7tupv	359	24	early	early	JJ
cord-256187-ofp7tupv	359	25	target	target	NN
cord-256187-ofp7tupv	359	26	cells	cell	NNS
cord-256187-ofp7tupv	359	27	in	in	IN
cord-256187-ofp7tupv	359	28	filovirus	filovirus	NN
cord-256187-ofp7tupv	359	29	infection	infection	NN
cord-256187-ofp7tupv	359	30	.	.	.
cord-256187-ofp7tupv	360	1	Further	further	JJ
cord-256187-ofp7tupv	360	2	research	research	NN
cord-256187-ofp7tupv	360	3	is	be	VBZ
cord-256187-ofp7tupv	360	4	needed	need	VBN
cord-256187-ofp7tupv	360	5	to	to	TO
cord-256187-ofp7tupv	360	6	define	define	VB
cord-256187-ofp7tupv	360	7	the	the	DT
cord-256187-ofp7tupv	360	8	basal	basal	JJ
cord-256187-ofp7tupv	360	9	expression	expression	NN
cord-256187-ofp7tupv	360	10	of	of	IN
cord-256187-ofp7tupv	360	11	IFITMs	ifitms	NN
cord-256187-ofp7tupv	360	12	in	in	IN
cord-256187-ofp7tupv	360	13	filovirus	filovirus	NN
cord-256187-ofp7tupv	360	14	target	target	NN
cord-256187-ofp7tupv	360	15	cells	cell	NNS
cord-256187-ofp7tupv	360	16	and	and	CC
cord-256187-ofp7tupv	360	17	to	to	TO
cord-256187-ofp7tupv	360	18	elucidate	elucidate	VB
cord-256187-ofp7tupv	360	19	the	the	DT
cord-256187-ofp7tupv	360	20	mechanism	mechanism	NN
cord-256187-ofp7tupv	360	21	by	by	IN
cord-256187-ofp7tupv	360	22	which	which	WDT
cord-256187-ofp7tupv	360	23	the	the	DT
cord-256187-ofp7tupv	360	24	different	different	JJ
cord-256187-ofp7tupv	360	25	IFITM	IFITM	NNP
cord-256187-ofp7tupv	360	26	proteins	protein	NNS
cord-256187-ofp7tupv	360	27	restrict	restrict	VBP
cord-256187-ofp7tupv	360	28	filovirus	filovirus	NN
cord-256187-ofp7tupv	360	29	infection	infection	NN
cord-256187-ofp7tupv	360	30	.	.	.
cord-256187-ofp7tupv	361	1	The	the	DT
cord-256187-ofp7tupv	361	2	IFN	IFN	NNP
cord-256187-ofp7tupv	361	3	system	system	NN
cord-256187-ofp7tupv	361	4	can	can	MD
cord-256187-ofp7tupv	361	5	potently	potently	RB
cord-256187-ofp7tupv	361	6	restrict	restrict	VB
cord-256187-ofp7tupv	361	7	EBOV	EBOV	NNP
cord-256187-ofp7tupv	361	8	spread	spread	VB
cord-256187-ofp7tupv	361	9	and	and	CC
cord-256187-ofp7tupv	361	10	pathogenesis	pathogenesis	NN
cord-256187-ofp7tupv	361	11	in	in	IN
cord-256187-ofp7tupv	361	12	infected	infected	JJ
cord-256187-ofp7tupv	361	13	mice	mouse	NNS
cord-256187-ofp7tupv	361	14	,	,	,
cord-256187-ofp7tupv	361	15	but	but	CC
cord-256187-ofp7tupv	361	16	is	be	VBZ
cord-256187-ofp7tupv	361	17	tuned	tune	VBN
cord-256187-ofp7tupv	361	18	down	down	RP
cord-256187-ofp7tupv	361	19	by	by	IN
cord-256187-ofp7tupv	361	20	viral	viral	JJ
cord-256187-ofp7tupv	361	21	proteins	protein	NNS
cord-256187-ofp7tupv	361	22	in	in	IN
cord-256187-ofp7tupv	361	23	infected	infected	JJ
cord-256187-ofp7tupv	361	24	humans	human	NNS
cord-256187-ofp7tupv	361	25	.	.	.
cord-256187-ofp7tupv	362	1	VP24	VP24	NNP
cord-256187-ofp7tupv	362	2	and	and	CC
cord-256187-ofp7tupv	362	3	VP35	VP35	NNP
cord-256187-ofp7tupv	362	4	play	play	VB
cord-256187-ofp7tupv	362	5	key	key	JJ
cord-256187-ofp7tupv	362	6	roles	role	NNS
cord-256187-ofp7tupv	362	7	in	in	IN
cord-256187-ofp7tupv	362	8	suppressing	suppress	VBG
cord-256187-ofp7tupv	362	9	the	the	DT
cord-256187-ofp7tupv	362	10	IFN	IFN	NNP
cord-256187-ofp7tupv	362	11	response	response	NN
cord-256187-ofp7tupv	362	12	by	by	IN
cord-256187-ofp7tupv	362	13	preventing	prevent	VBG
cord-256187-ofp7tupv	362	14	nuclear	nuclear	JJ
cord-256187-ofp7tupv	362	15	translocation	translocation	NN
cord-256187-ofp7tupv	362	16	of	of	IN
cord-256187-ofp7tupv	362	17	STAT1	stat1	NN
cord-256187-ofp7tupv	362	18	and	and	CC
cord-256187-ofp7tupv	362	19	by	by	IN
cord-256187-ofp7tupv	362	20	targeting	target	VBG
cord-256187-ofp7tupv	362	21	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	362	22	and	and	CC
cord-256187-ofp7tupv	362	23	IRF-7	IRF-7	NNP
cord-256187-ofp7tupv	362	24	,	,	,
cord-256187-ofp7tupv	362	25	respectively	respectively	RB
cord-256187-ofp7tupv	362	26	.	.	.
cord-256187-ofp7tupv	363	1	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	363	2	and	and	CC
cord-256187-ofp7tupv	363	3	IFITM	IFITM	NNP
cord-256187-ofp7tupv	363	4	proteins	protein	NNS
cord-256187-ofp7tupv	363	5	are	be	VBP
cord-256187-ofp7tupv	363	6	novel	novel	JJ
cord-256187-ofp7tupv	363	7	ISGs	isg	NNS
cord-256187-ofp7tupv	363	8	,	,	,
cord-256187-ofp7tupv	363	9	which	which	WDT
cord-256187-ofp7tupv	363	10	could	could	MD
cord-256187-ofp7tupv	363	11	suppress	suppress	VB
cord-256187-ofp7tupv	363	12	EBOV	EBOV	NNP
cord-256187-ofp7tupv	363	13	infectious	infectious	JJ
cord-256187-ofp7tupv	363	14	entry	entry	NN
cord-256187-ofp7tupv	363	15	into	into	IN
cord-256187-ofp7tupv	363	16	target	target	NN
cord-256187-ofp7tupv	363	17	cells	cell	NNS
cord-256187-ofp7tupv	363	18	(	(	-LRB-
cord-256187-ofp7tupv	363	19	IFITMs	ifitms	NN
cord-256187-ofp7tupv	363	20	)	)	-RRB-
cord-256187-ofp7tupv	363	21	and	and	CC
cord-256187-ofp7tupv	363	22	release	release	NN
cord-256187-ofp7tupv	363	23	of	of	IN
cord-256187-ofp7tupv	363	24	EBOV	EBOV	NNP
cord-256187-ofp7tupv	363	25	particles	particle	NNS
cord-256187-ofp7tupv	363	26	from	from	IN
cord-256187-ofp7tupv	363	27	infected	infected	JJ
cord-256187-ofp7tupv	363	28	cells	cell	NNS
cord-256187-ofp7tupv	363	29	(	(	-LRB-
cord-256187-ofp7tupv	363	30	tetherin	tetherin	NNP
cord-256187-ofp7tupv	363	31	)	)	-RRB-
cord-256187-ofp7tupv	363	32	.	.	.
cord-256187-ofp7tupv	364	1	Efficient	efficient	JJ
cord-256187-ofp7tupv	364	2	suppression	suppression	NN
cord-256187-ofp7tupv	364	3	of	of	IN
cord-256187-ofp7tupv	364	4	EBOV	EBOV	NNP
cord-256187-ofp7tupv	364	5	release	release	NN
cord-256187-ofp7tupv	364	6	has	have	VBZ
cord-256187-ofp7tupv	364	7	so	so	RB
cord-256187-ofp7tupv	364	8	far	far	RB
cord-256187-ofp7tupv	364	9	only	only	RB
cord-256187-ofp7tupv	364	10	been	be	VBN
cord-256187-ofp7tupv	364	11	demonstrated	demonstrate	VBN
cord-256187-ofp7tupv	364	12	with	with	IN
cord-256187-ofp7tupv	364	13	VLPs	vlp	NNS
cord-256187-ofp7tupv	364	14	and	and	CC
cord-256187-ofp7tupv	364	15	remains	remain	VBZ
cord-256187-ofp7tupv	364	16	to	to	TO
cord-256187-ofp7tupv	364	17	be	be	VB
cord-256187-ofp7tupv	364	18	shown	show	VBN
cord-256187-ofp7tupv	364	19	with	with	IN
cord-256187-ofp7tupv	364	20	infectious	infectious	JJ
cord-256187-ofp7tupv	364	21	EBOV	EBOV	NNS
cord-256187-ofp7tupv	364	22	.	.	.
cord-256187-ofp7tupv	365	1	For	for	IN
cord-256187-ofp7tupv	365	2	this	this	DT
cord-256187-ofp7tupv	365	3	,	,	,
cord-256187-ofp7tupv	365	4	the	the	DT
cord-256187-ofp7tupv	365	5	sequences	sequence	NNS
cord-256187-ofp7tupv	365	6	in	in	IN
cord-256187-ofp7tupv	365	7	GP	GP	NNP
cord-256187-ofp7tupv	365	8	1,2	1,2	CD
cord-256187-ofp7tupv	365	9	,	,	,
cord-256187-ofp7tupv	365	10	which	which	WDT
cord-256187-ofp7tupv	365	11	facilitate	facilitate	VBP
cord-256187-ofp7tupv	365	12	tetherin	tetherin	NN
cord-256187-ofp7tupv	365	13	antagonism	antagonism	NN
cord-256187-ofp7tupv	365	14	,	,	,
cord-256187-ofp7tupv	365	15	need	need	VBP
cord-256187-ofp7tupv	365	16	to	to	TO
cord-256187-ofp7tupv	365	17	be	be	VB
cord-256187-ofp7tupv	365	18	identified	identify	VBN
cord-256187-ofp7tupv	365	19	and	and	CC
cord-256187-ofp7tupv	365	20	altered	alter	VBN
cord-256187-ofp7tupv	365	21	,	,	,
cord-256187-ofp7tupv	365	22	which	which	WDT
cord-256187-ofp7tupv	365	23	should	should	MD
cord-256187-ofp7tupv	365	24	render	render	VB
cord-256187-ofp7tupv	365	25	EBOV	EBOV	NNP
cord-256187-ofp7tupv	365	26	susceptible	susceptible	JJ
cord-256187-ofp7tupv	365	27	to	to	IN
cord-256187-ofp7tupv	365	28	inhibition	inhibition	NN
cord-256187-ofp7tupv	365	29	by	by	IN
cord-256187-ofp7tupv	365	30	tetherin	tetherin	NNP
cord-256187-ofp7tupv	365	31	.	.	.
cord-256187-ofp7tupv	366	1	The	the	DT
cord-256187-ofp7tupv	366	2	GP	GP	NNP
cord-256187-ofp7tupv	366	3	2	2	CD
cord-256187-ofp7tupv	366	4	subunit	subunit	NN
cord-256187-ofp7tupv	366	5	is	be	VBZ
cord-256187-ofp7tupv	366	6	an	an	DT
cord-256187-ofp7tupv	366	7	excellent	excellent	JJ
cord-256187-ofp7tupv	366	8	candidate	candidate	NN
cord-256187-ofp7tupv	366	9	for	for	IN
cord-256187-ofp7tupv	366	10	these	these	DT
cord-256187-ofp7tupv	366	11	endeavours	endeavour	NNS
cord-256187-ofp7tupv	366	12	(	(	-LRB-
cord-256187-ofp7tupv	366	13	Kühl	Kühl	NNP
cord-256187-ofp7tupv	366	14	et	et	FW
cord-256187-ofp7tupv	366	15	al	al	NNP
cord-256187-ofp7tupv	366	16	.	.	NNP
cord-256187-ofp7tupv	366	17	,	,	,
cord-256187-ofp7tupv	366	18	2011a	2011a	CD
cord-256187-ofp7tupv	366	19	)	)	-RRB-
cord-256187-ofp7tupv	366	20	.	.	.
cord-256187-ofp7tupv	367	1	The	the	DT
cord-256187-ofp7tupv	367	2	mechanism	mechanism	NN
cord-256187-ofp7tupv	367	3	underlying	underlie	VBG
cord-256187-ofp7tupv	367	4	EBOV	EBOV	NNP
cord-256187-ofp7tupv	367	5	inhibition	inhibition	NN
cord-256187-ofp7tupv	367	6	by	by	IN
cord-256187-ofp7tupv	367	7	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	367	8	is	be	VBZ
cord-256187-ofp7tupv	367	9	at	at	IN
cord-256187-ofp7tupv	367	10	present	present	JJ
cord-256187-ofp7tupv	367	11	unknown	unknown	NN
cord-256187-ofp7tupv	367	12	,	,	,
cord-256187-ofp7tupv	367	13	and	and	CC
cord-256187-ofp7tupv	367	14	its	-PRON-	PRP$
cord-256187-ofp7tupv	367	15	elucidation	elucidation	NN
cord-256187-ofp7tupv	367	16	might	may	MD
cord-256187-ofp7tupv	367	17	require	require	VB
cord-256187-ofp7tupv	367	18	the	the	DT
cord-256187-ofp7tupv	367	19	identification	identification	NN
cord-256187-ofp7tupv	367	20	of	of	IN
cord-256187-ofp7tupv	367	21	potential	potential	JJ
cord-256187-ofp7tupv	367	22	interaction	interaction	NN
cord-256187-ofp7tupv	367	23	partners	partner	NNS
cord-256187-ofp7tupv	367	24	of	of	IN
cord-256187-ofp7tupv	367	25	GP	GP	NNP
cord-256187-ofp7tupv	367	26	1,2	1,2	CD
cord-256187-ofp7tupv	367	27	and	and	CC
cord-256187-ofp7tupv	367	28	IFITMs	ifitm	NNS
cord-256187-ofp7tupv	367	29	in	in	IN
cord-256187-ofp7tupv	367	30	host	host	NN
cord-256187-ofp7tupv	367	31	cell	cell	NN
cord-256187-ofp7tupv	367	32	endosomes	endosome	NNS
cord-256187-ofp7tupv	367	33	.	.	.
cord-256187-ofp7tupv	368	1	In	in	IN
cord-256187-ofp7tupv	368	2	addition	addition	NN
cord-256187-ofp7tupv	368	3	,	,	,
cord-256187-ofp7tupv	368	4	it	-PRON-	PRP
cord-256187-ofp7tupv	368	5	will	will	MD
cord-256187-ofp7tupv	368	6	be	be	VB
cord-256187-ofp7tupv	368	7	interesting	interesting	JJ
cord-256187-ofp7tupv	368	8	to	to	TO
cord-256187-ofp7tupv	368	9	determine	determine	VB
cord-256187-ofp7tupv	368	10	to	to	TO
cord-256187-ofp7tupv	368	11	which	which	WDT
cord-256187-ofp7tupv	368	12	extent	extent	NN
cord-256187-ofp7tupv	368	13	basal	basal	NN
cord-256187-ofp7tupv	368	14	(	(	-LRB-
cord-256187-ofp7tupv	368	15	in	in	IN
cord-256187-ofp7tupv	368	16	the	the	DT
cord-256187-ofp7tupv	368	17	absence	absence	NN
cord-256187-ofp7tupv	368	18	of	of	IN
cord-256187-ofp7tupv	368	19	IFN	IFN	NNP
cord-256187-ofp7tupv	368	20	)	)	-RRB-
cord-256187-ofp7tupv	368	21	expression	expression	NN
cord-256187-ofp7tupv	368	22	of	of	IN
cord-256187-ofp7tupv	368	23	IFITMs	IFITMs	NNPS
cord-256187-ofp7tupv	368	24	and	and	CC
cord-256187-ofp7tupv	368	25	tetherin	tetherin	VB
cord-256187-ofp7tupv	368	26	impact	impact	NN
cord-256187-ofp7tupv	368	27	EBOV	EBOV	NNP
cord-256187-ofp7tupv	368	28	spread	spread	VBD
cord-256187-ofp7tupv	368	29	.	.	.
cord-256187-ofp7tupv	369	1	A	a	DT
cord-256187-ofp7tupv	369	2	recent	recent	JJ
cord-256187-ofp7tupv	369	3	study	study	NN
cord-256187-ofp7tupv	369	4	demonstrated	demonstrate	VBD
cord-256187-ofp7tupv	369	5	that	that	IN
cord-256187-ofp7tupv	369	6	basal	basal	NN
cord-256187-ofp7tupv	369	7	tetherin	tetherin	NN
cord-256187-ofp7tupv	369	8	expression	expression	NN
cord-256187-ofp7tupv	369	9	is	be	VBZ
cord-256187-ofp7tupv	369	10	broader	broad	JJR
cord-256187-ofp7tupv	369	11	than	than	IN
cord-256187-ofp7tupv	369	12	initially	initially	RB
cord-256187-ofp7tupv	369	13	appreciated	appreciate	VBN
cord-256187-ofp7tupv	369	14	and	and	CC
cord-256187-ofp7tupv	369	15	raised	raise	VBD
cord-256187-ofp7tupv	369	16	doubts	doubt	NNS
cord-256187-ofp7tupv	369	17	concerning	concern	VBG
cord-256187-ofp7tupv	369	18	the	the	DT
cord-256187-ofp7tupv	369	19	sole	sole	JJ
cord-256187-ofp7tupv	369	20	regulation	regulation	NN
cord-256187-ofp7tupv	369	21	of	of	IN
cord-256187-ofp7tupv	369	22	tetherin	tetherin	NN
cord-256187-ofp7tupv	369	23	expression	expression	NN
cord-256187-ofp7tupv	369	24	by	by	IN
cord-256187-ofp7tupv	369	25	IFNs	ifn	NNS
cord-256187-ofp7tupv	369	26	(	(	-LRB-
cord-256187-ofp7tupv	369	27	Erikson	Erikson	NNP
cord-256187-ofp7tupv	369	28	et	et	NNP
cord-256187-ofp7tupv	369	29	al	al	NNP
cord-256187-ofp7tupv	369	30	.	.	NNP
cord-256187-ofp7tupv	369	31	,	,	,
cord-256187-ofp7tupv	369	32	2011	2011	CD
cord-256187-ofp7tupv	369	33	)	)	-RRB-
cord-256187-ofp7tupv	369	34	.	.	.
cord-256187-ofp7tupv	370	1	Moreover	moreover	RB
cord-256187-ofp7tupv	370	2	,	,	,
cord-256187-ofp7tupv	370	3	the	the	DT
cord-256187-ofp7tupv	370	4	role	role	NN
cord-256187-ofp7tupv	370	5	of	of	IN
cord-256187-ofp7tupv	370	6	the	the	DT
cord-256187-ofp7tupv	370	7	IFN	IFN	NNP
cord-256187-ofp7tupv	370	8	system	system	NN
cord-256187-ofp7tupv	370	9	in	in	IN
cord-256187-ofp7tupv	370	10	the	the	DT
cord-256187-ofp7tupv	370	11	EBOV	EBOV	NNP
cord-256187-ofp7tupv	370	12	infection	infection	NN
cord-256187-ofp7tupv	370	13	of	of	IN
cord-256187-ofp7tupv	370	14	the	the	DT
cord-256187-ofp7tupv	370	15	potential	potential	JJ
cord-256187-ofp7tupv	370	16	reservoir	reservoir	NN
cord-256187-ofp7tupv	370	17	host	host	NN
cord-256187-ofp7tupv	370	18	,	,	,
cord-256187-ofp7tupv	370	19	fruit	fruit	NN
cord-256187-ofp7tupv	370	20	bats	bat	NNS
cord-256187-ofp7tupv	370	21	(	(	-LRB-
cord-256187-ofp7tupv	370	22	Leroy	Leroy	NNP
cord-256187-ofp7tupv	370	23	et	et	NNP
cord-256187-ofp7tupv	370	24	al	al	NNP
cord-256187-ofp7tupv	370	25	.	.	NNP
cord-256187-ofp7tupv	370	26	,	,	,
cord-256187-ofp7tupv	370	27	2005	2005	CD
cord-256187-ofp7tupv	370	28	)	)	-RRB-
cord-256187-ofp7tupv	370	29	,	,	,
cord-256187-ofp7tupv	370	30	is	be	VBZ
cord-256187-ofp7tupv	370	31	of	of	IN
cord-256187-ofp7tupv	370	32	high	high	JJ
cord-256187-ofp7tupv	370	33	interest	interest	NN
cord-256187-ofp7tupv	370	34	.	.	.
cord-256187-ofp7tupv	371	1	Thus	thus	RB
cord-256187-ofp7tupv	371	2	,	,	,
cord-256187-ofp7tupv	371	3	EBOV	EBOV	NNP
cord-256187-ofp7tupv	371	4	infection	infection	NN
cord-256187-ofp7tupv	371	5	of	of	IN
cord-256187-ofp7tupv	371	6	these	these	DT
cord-256187-ofp7tupv	371	7	animals	animal	NNS
cord-256187-ofp7tupv	371	8	does	do	VBZ
cord-256187-ofp7tupv	371	9	not	not	RB
cord-256187-ofp7tupv	371	10	seem	seem	VB
cord-256187-ofp7tupv	371	11	to	to	TO
cord-256187-ofp7tupv	371	12	induce	induce	VB
cord-256187-ofp7tupv	371	13	disease	disease	NN
cord-256187-ofp7tupv	371	14	(	(	-LRB-
cord-256187-ofp7tupv	371	15	Swanepoel	Swanepoel	NNP
cord-256187-ofp7tupv	371	16	et	et	FW
cord-256187-ofp7tupv	371	17	al	al	NNP
cord-256187-ofp7tupv	371	18	.	.	NNP
cord-256187-ofp7tupv	371	19	,	,	,
cord-256187-ofp7tupv	371	20	1996	1996	CD
cord-256187-ofp7tupv	371	21	;	;	:
cord-256187-ofp7tupv	371	22	Hayman	Hayman	NNP
cord-256187-ofp7tupv	371	23	et	et	NNP
cord-256187-ofp7tupv	371	24	al	al	NNP
cord-256187-ofp7tupv	371	25	.	.	NNP
cord-256187-ofp7tupv	371	26	,	,	,
cord-256187-ofp7tupv	371	27	2010	2010	CD
cord-256187-ofp7tupv	371	28	)	)	-RRB-
cord-256187-ofp7tupv	371	29	,	,	,
cord-256187-ofp7tupv	371	30	and	and	CC
cord-256187-ofp7tupv	371	31	it	-PRON-	PRP
cord-256187-ofp7tupv	371	32	is	be	VBZ
cord-256187-ofp7tupv	371	33	tempting	tempt	VBG
cord-256187-ofp7tupv	371	34	to	to	TO
cord-256187-ofp7tupv	371	35	speculate	speculate	VB
cord-256187-ofp7tupv	371	36	that	that	IN
cord-256187-ofp7tupv	371	37	the	the	DT
cord-256187-ofp7tupv	371	38	bat	bat	NN
cord-256187-ofp7tupv	371	39	IFN	IFN	NNP
cord-256187-ofp7tupv	371	40	system	system	NN
cord-256187-ofp7tupv	371	41	efficiently	efficiently	RB
cord-256187-ofp7tupv	371	42	controls	control	VBZ
cord-256187-ofp7tupv	371	43	viral	viral	JJ
cord-256187-ofp7tupv	371	44	replication	replication	NN
cord-256187-ofp7tupv	371	45	.	.	.
cord-256187-ofp7tupv	372	1	Finally	finally	RB
cord-256187-ofp7tupv	372	2	,	,	,
cord-256187-ofp7tupv	372	3	the	the	DT
cord-256187-ofp7tupv	372	4	interesting	interesting	JJ
cord-256187-ofp7tupv	372	5	insights	insight	NNS
cord-256187-ofp7tupv	372	6	into	into	IN
cord-256187-ofp7tupv	372	7	EBOV	EBOV	NNP
cord-256187-ofp7tupv	372	8	interference	interference	NN
cord-256187-ofp7tupv	372	9	with	with	IN
cord-256187-ofp7tupv	372	10	the	the	DT
cord-256187-ofp7tupv	372	11	IFN	IFN	NNP
cord-256187-ofp7tupv	372	12	system	system	NN
cord-256187-ofp7tupv	372	13	open	open	VBP
cord-256187-ofp7tupv	372	14	new	new	JJ
cord-256187-ofp7tupv	372	15	avenues	avenue	NNS
cord-256187-ofp7tupv	372	16	to	to	IN
cord-256187-ofp7tupv	372	17	the	the	DT
cord-256187-ofp7tupv	372	18	development	development	NN
cord-256187-ofp7tupv	372	19	of	of	IN
cord-256187-ofp7tupv	372	20	filovirus	filovirus	NN
cord-256187-ofp7tupv	372	21	inhibitors	inhibitor	NNS
cord-256187-ofp7tupv	372	22	.	.	.
cord-256187-ofp7tupv	373	1	Proof	proof	NN
cord-256187-ofp7tupv	373	2	of	of	IN
cord-256187-ofp7tupv	373	3	concept	concept	NN
cord-256187-ofp7tupv	373	4	comes	come	VBZ
cord-256187-ofp7tupv	373	5	from	from	IN
cord-256187-ofp7tupv	373	6	studies	study	NNS
cord-256187-ofp7tupv	373	7	with	with	IN
cord-256187-ofp7tupv	373	8	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	373	9	,	,	,
cord-256187-ofp7tupv	373	10	which	which	WDT
cord-256187-ofp7tupv	373	11	demonstrated	demonstrate	VBD
cord-256187-ofp7tupv	373	12	that	that	IN
cord-256187-ofp7tupv	373	13	stabilization	stabilization	NN
cord-256187-ofp7tupv	373	14	of	of	IN
cord-256187-ofp7tupv	373	15	antiviral	antiviral	JJ
cord-256187-ofp7tupv	373	16	effectors	effector	NNS
cord-256187-ofp7tupv	373	17	molecules	molecule	NNS
cord-256187-ofp7tupv	373	18	of	of	IN
cord-256187-ofp7tupv	373	19	the	the	DT
cord-256187-ofp7tupv	373	20	IFN	IFN	NNP
cord-256187-ofp7tupv	373	21	system	system	NN
cord-256187-ofp7tupv	373	22	or	or	CC
cord-256187-ofp7tupv	373	23	inhibition	inhibition	NN
cord-256187-ofp7tupv	373	24	of	of	IN
cord-256187-ofp7tupv	373	25	viral	viral	JJ
cord-256187-ofp7tupv	373	26	IFN	IFN	NNP
cord-256187-ofp7tupv	373	27	antagonists	antagonist	NNS
cord-256187-ofp7tupv	373	28	by	by	IN
cord-256187-ofp7tupv	373	29	small	small	JJ
cord-256187-ofp7tupv	373	30	molecules	molecule	NNS
cord-256187-ofp7tupv	373	31	can	can	MD
cord-256187-ofp7tupv	373	32	suppress	suppress	VB
cord-256187-ofp7tupv	373	33	viral	viral	JJ
cord-256187-ofp7tupv	373	34	spread	spread	NN
cord-256187-ofp7tupv	373	35	(	(	-LRB-
cord-256187-ofp7tupv	373	36	Cen	Cen	NNP
cord-256187-ofp7tupv	373	37	et	et	FW
cord-256187-ofp7tupv	373	38	al	al	NNP
cord-256187-ofp7tupv	373	39	.	.	NNP
cord-256187-ofp7tupv	373	40	,	,	,
cord-256187-ofp7tupv	373	41	2010	2010	CD
cord-256187-ofp7tupv	373	42	;	;	:
cord-256187-ofp7tupv	373	43	Jiang	Jiang	NNP
cord-256187-ofp7tupv	373	44	et	et	FW
cord-256187-ofp7tupv	373	45	al	al	NNP
cord-256187-ofp7tupv	373	46	.	.	NNP
cord-256187-ofp7tupv	373	47	,	,	,
cord-256187-ofp7tupv	373	48	2010	2010	CD
cord-256187-ofp7tupv	373	49	)	)	-RRB-
cord-256187-ofp7tupv	373	50	.	.	.
cord-256187-ofp7tupv	374	1	The	the	DT
cord-256187-ofp7tupv	374	2	authors	author	NNS
cord-256187-ofp7tupv	374	3	have	have	VBP
cord-256187-ofp7tupv	374	4	no	no	DT
cord-256187-ofp7tupv	374	5	potential	potential	JJ
cord-256187-ofp7tupv	374	6	conflicts	conflict	NNS
cord-256187-ofp7tupv	374	7	to	to	TO
cord-256187-ofp7tupv	374	8	declare	declare	VB
cord-256187-ofp7tupv	374	9	.	.	.
cord-256187-ofp7tupv	375	1	The	the	DT
cord-256187-ofp7tupv	375	2	Ebola	Ebola	NNP
cord-256187-ofp7tupv	375	3	virus	virus	NN
cord-256187-ofp7tupv	375	4	VP35	VP35	NNP
cord-256187-ofp7tupv	375	5	protein	protein	NN
cord-256187-ofp7tupv	375	6	functions	function	NNS
cord-256187-ofp7tupv	375	7	as	as	IN
cord-256187-ofp7tupv	375	8	a	a	DT
cord-256187-ofp7tupv	375	9	type	type	NN
cord-256187-ofp7tupv	375	10	I	-PRON-	PRP
cord-256187-ofp7tupv	375	11	IFN	IFN	NNP
cord-256187-ofp7tupv	375	12	antagonist	antagonist	NN
cord-256187-ofp7tupv	376	1	The	the	DT
cord-256187-ofp7tupv	376	2	Ebola	Ebola	NNP
cord-256187-ofp7tupv	376	3	virus	virus	NN
cord-256187-ofp7tupv	376	4	VP35	VP35	NNP
cord-256187-ofp7tupv	376	5	protein	protein	NN
cord-256187-ofp7tupv	376	6	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	376	7	activation	activation	NN
cord-256187-ofp7tupv	376	8	of	of	IN
cord-256187-ofp7tupv	376	9	interferon	interferon	NN
cord-256187-ofp7tupv	376	10	regulatory	regulatory	JJ
cord-256187-ofp7tupv	376	11	factor	factor	NN
cord-256187-ofp7tupv	376	12	3	3	CD
cord-256187-ofp7tupv	376	13	Induction	Induction	NNP
cord-256187-ofp7tupv	376	14	of	of	IN
cord-256187-ofp7tupv	376	15	type	type	NN
cord-256187-ofp7tupv	377	1	I	-PRON-	PRP
cord-256187-ofp7tupv	377	2	interferon	interferon	RB
cord-256187-ofp7tupv	377	3	by	by	IN
cord-256187-ofp7tupv	377	4	RNA	RNA	NNP
cord-256187-ofp7tupv	377	5	viruses	virus	NNS
cord-256187-ofp7tupv	377	6	:	:	:
cord-256187-ofp7tupv	377	7	cellular	cellular	JJ
cord-256187-ofp7tupv	377	8	receptors	receptor	NNS
cord-256187-ofp7tupv	377	9	and	and	CC
cord-256187-ofp7tupv	377	10	their	-PRON-	PRP$
cord-256187-ofp7tupv	377	11	substrates	substrate	NNS
cord-256187-ofp7tupv	378	1	Differential	differential	JJ
cord-256187-ofp7tupv	378	2	recognition	recognition	NN
cord-256187-ofp7tupv	378	3	of	of	IN
cord-256187-ofp7tupv	378	4	viral	viral	JJ
cord-256187-ofp7tupv	378	5	RNA	RNA	NNP
cord-256187-ofp7tupv	378	6	by	by	IN
cord-256187-ofp7tupv	378	7	RIG-	RIG-	NNP
cord-256187-ofp7tupv	379	1	I	-PRON-	PRP
cord-256187-ofp7tupv	379	2	Lipid	Lipid	NNP
cord-256187-ofp7tupv	379	3	raft	raft	NN
cord-256187-ofp7tupv	379	4	microdomains	microdomain	NNS
cord-256187-ofp7tupv	379	5	:	:	:
cord-256187-ofp7tupv	379	6	a	a	DT
cord-256187-ofp7tupv	379	7	gateway	gateway	NN
cord-256187-ofp7tupv	379	8	for	for	IN
cord-256187-ofp7tupv	379	9	compartmentalized	compartmentalized	JJ
cord-256187-ofp7tupv	379	10	trafficking	trafficking	NN
cord-256187-ofp7tupv	379	11	of	of	IN
cord-256187-ofp7tupv	379	12	Ebola	Ebola	NNP
cord-256187-ofp7tupv	379	13	and	and	CC
cord-256187-ofp7tupv	379	14	Marburg	Marburg	NNP
cord-256187-ofp7tupv	379	15	viruses	virus	NNS
cord-256187-ofp7tupv	379	16	Viral	Viral	NNP
cord-256187-ofp7tupv	379	17	RNA	RNA	NNP
cord-256187-ofp7tupv	379	18	silencing	silence	VBG
cord-256187-ofp7tupv	379	19	suppressors	suppressor	NNS
cord-256187-ofp7tupv	379	20	(	(	-LRB-
cord-256187-ofp7tupv	379	21	RSS	RSS	NNP
cord-256187-ofp7tupv	379	22	)	)	-RRB-
cord-256187-ofp7tupv	379	23	:	:	:
cord-256187-ofp7tupv	380	1	novel	novel	JJ
cord-256187-ofp7tupv	380	2	strategy	strategy	NN
cord-256187-ofp7tupv	380	3	of	of	IN
cord-256187-ofp7tupv	380	4	viruses	virus	NNS
cord-256187-ofp7tupv	380	5	to	to	TO
cord-256187-ofp7tupv	380	6	ablate	ablate	VB
cord-256187-ofp7tupv	380	7	the	the	DT
cord-256187-ofp7tupv	380	8	host	host	NN
cord-256187-ofp7tupv	380	9	RNA	RNA	NNP
cord-256187-ofp7tupv	380	10	interference	interference	NN
cord-256187-ofp7tupv	380	11	(	(	-LRB-
cord-256187-ofp7tupv	380	12	RNAi	RNAi	NNP
cord-256187-ofp7tupv	380	13	)	)	-RRB-
cord-256187-ofp7tupv	380	14	defense	defense	NN
cord-256187-ofp7tupv	380	15	system	system	NN
cord-256187-ofp7tupv	381	1	The	the	DT
cord-256187-ofp7tupv	381	2	IFITM	IFITM	NNP
cord-256187-ofp7tupv	381	3	proteins	protein	NNS
cord-256187-ofp7tupv	381	4	mediate	mediate	VBP
cord-256187-ofp7tupv	381	5	cellular	cellular	JJ
cord-256187-ofp7tupv	381	6	resistance	resistance	NN
cord-256187-ofp7tupv	381	7	to	to	TO
cord-256187-ofp7tupv	381	8	influenza	influenza	VB
cord-256187-ofp7tupv	381	9	A	a	DT
cord-256187-ofp7tupv	381	10	H1N1	H1N1	NNP
cord-256187-ofp7tupv	381	11	virus	virus	NN
cord-256187-ofp7tupv	381	12	,	,	,
cord-256187-ofp7tupv	381	13	West	West	NNP
cord-256187-ofp7tupv	381	14	Nile	Nile	NNP
cord-256187-ofp7tupv	381	15	virus	virus	NN
cord-256187-ofp7tupv	381	16	,	,	,
cord-256187-ofp7tupv	381	17	and	and	CC
cord-256187-ofp7tupv	381	18	dengue	dengue	NN
cord-256187-ofp7tupv	381	19	virus	virus	NN
cord-256187-ofp7tupv	382	1	The	the	DT
cord-256187-ofp7tupv	382	2	role	role	NN
cord-256187-ofp7tupv	382	3	of	of	IN
cord-256187-ofp7tupv	382	4	the	the	DT
cord-256187-ofp7tupv	382	5	Type	type	NN
cord-256187-ofp7tupv	382	6	I	-PRON-	PRP
cord-256187-ofp7tupv	382	7	interferon	interferon	VBD
cord-256187-ofp7tupv	382	8	response	response	NN
cord-256187-ofp7tupv	382	9	in	in	IN
cord-256187-ofp7tupv	382	10	the	the	DT
cord-256187-ofp7tupv	382	11	resistance	resistance	NN
cord-256187-ofp7tupv	382	12	of	of	IN
cord-256187-ofp7tupv	382	13	mice	mouse	NNS
cord-256187-ofp7tupv	382	14	to	to	IN
cord-256187-ofp7tupv	382	15	filovirus	filovirus	NN
cord-256187-ofp7tupv	382	16	infection	infection	NN
cord-256187-ofp7tupv	383	1	A	a	DT
cord-256187-ofp7tupv	383	2	mouse	mouse	NN
cord-256187-ofp7tupv	383	3	model	model	NN
cord-256187-ofp7tupv	383	4	for	for	IN
cord-256187-ofp7tupv	383	5	evaluation	evaluation	NN
cord-256187-ofp7tupv	383	6	of	of	IN
cord-256187-ofp7tupv	383	7	prophylaxis	prophylaxis	NN
cord-256187-ofp7tupv	383	8	and	and	CC
cord-256187-ofp7tupv	383	9	therapy	therapy	NN
cord-256187-ofp7tupv	383	10	of	of	IN
cord-256187-ofp7tupv	383	11	Ebola	Ebola	NNP
cord-256187-ofp7tupv	383	12	hemorrhagic	hemorrhagic	JJ
cord-256187-ofp7tupv	383	13	fever	fever	NN
cord-256187-ofp7tupv	383	14	Ebola	Ebola	NNP
cord-256187-ofp7tupv	383	15	virus	virus	NN
cord-256187-ofp7tupv	383	16	VP35	VP35	NNP
cord-256187-ofp7tupv	383	17	protein	protein	NN
cord-256187-ofp7tupv	383	18	binds	bind	VBZ
cord-256187-ofp7tupv	383	19	doublestranded	doublestranded	JJ
cord-256187-ofp7tupv	383	20	RNA	RNA	NNP
cord-256187-ofp7tupv	383	21	and	and	CC
cord-256187-ofp7tupv	383	22	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	383	23	alpha	alpha	NN
cord-256187-ofp7tupv	383	24	/	/	SYM
cord-256187-ofp7tupv	383	25	beta	beta	NN
cord-256187-ofp7tupv	383	26	interferon	interferon	NN
cord-256187-ofp7tupv	383	27	production	production	NN
cord-256187-ofp7tupv	383	28	induced	induce	VBN
cord-256187-ofp7tupv	383	29	by	by	IN
cord-256187-ofp7tupv	383	30	RIG	rig	NN
cord-256187-ofp7tupv	384	1	-I	-i	DT
cord-256187-ofp7tupv	384	2	signaling	signal	VBG
cord-256187-ofp7tupv	384	3	Ebola	Ebola	NNP
cord-256187-ofp7tupv	384	4	virus	virus	NN
cord-256187-ofp7tupv	384	5	entry	entry	NN
cord-256187-ofp7tupv	384	6	requires	require	VBZ
cord-256187-ofp7tupv	384	7	the	the	DT
cord-256187-ofp7tupv	384	8	cholesterol	cholesterol	NN
cord-256187-ofp7tupv	384	9	transporter	transporter	NN
cord-256187-ofp7tupv	384	10	Niemann	Niemann	NNP
cord-256187-ofp7tupv	384	11	-	-	HYPH
cord-256187-ofp7tupv	384	12	Pick	Pick	NNP
cord-256187-ofp7tupv	384	13	C1	C1	NNP
cord-256187-ofp7tupv	384	14	Small	small	JJ
cord-256187-ofp7tupv	384	15	molecular	molecular	JJ
cord-256187-ofp7tupv	384	16	compounds	compound	NNS
cord-256187-ofp7tupv	384	17	inhibit	inhibit	VBP
cord-256187-ofp7tupv	384	18	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	384	19	replication	replication	NN
cord-256187-ofp7tupv	384	20	through	through	IN
cord-256187-ofp7tupv	384	21	specifically	specifically	RB
cord-256187-ofp7tupv	384	22	stabilizing	stabilize	VBG
cord-256187-ofp7tupv	384	23	APOBEC3	apobec3	DT
cord-256187-ofp7tupv	384	24	G	G	NNP
cord-256187-ofp7tupv	384	25	Endosomal	Endosomal	NNP
cord-256187-ofp7tupv	384	26	proteolysis	proteolysis	NN
cord-256187-ofp7tupv	384	27	of	of	IN
cord-256187-ofp7tupv	384	28	the	the	DT
cord-256187-ofp7tupv	384	29	Ebola	Ebola	NNP
cord-256187-ofp7tupv	384	30	virus	virus	NN
cord-256187-ofp7tupv	384	31	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	384	32	is	be	VBZ
cord-256187-ofp7tupv	384	33	necessary	necessary	JJ
cord-256187-ofp7tupv	384	34	for	for	IN
cord-256187-ofp7tupv	384	35	infection	infection	NN
cord-256187-ofp7tupv	385	1	Ebola	Ebola	NNP
cord-256187-ofp7tupv	385	2	Zaire	Zaire	NNP
cord-256187-ofp7tupv	385	3	virus	virus	NN
cord-256187-ofp7tupv	385	4	blocks	block	VBZ
cord-256187-ofp7tupv	385	5	type	type	NN
cord-256187-ofp7tupv	386	1	I	-PRON-	PRP
cord-256187-ofp7tupv	387	1	interferon	interferon	NN
cord-256187-ofp7tupv	387	2	production	production	NN
cord-256187-ofp7tupv	387	3	by	by	IN
cord-256187-ofp7tupv	387	4	exploiting	exploit	VBG
cord-256187-ofp7tupv	387	5	the	the	DT
cord-256187-ofp7tupv	387	6	host	host	NN
cord-256187-ofp7tupv	387	7	SUMO	SUMO	NNP
cord-256187-ofp7tupv	387	8	modification	modification	NN
cord-256187-ofp7tupv	387	9	machinery	machinery	NN
cord-256187-ofp7tupv	387	10	Small	small	JJ
cord-256187-ofp7tupv	387	11	molecule	molecule	NN
cord-256187-ofp7tupv	387	12	inhibitors	inhibitor	NNS
cord-256187-ofp7tupv	387	13	reveal	reveal	VBP
cord-256187-ofp7tupv	387	14	Niemann	Niemann	NNP
cord-256187-ofp7tupv	387	15	-	-	HYPH
cord-256187-ofp7tupv	387	16	Pick	Pick	NNP
cord-256187-ofp7tupv	387	17	C1	C1	NNP
cord-256187-ofp7tupv	387	18	is	be	VBZ
cord-256187-ofp7tupv	387	19	essential	essential	JJ
cord-256187-ofp7tupv	387	20	for	for	IN
cord-256187-ofp7tupv	387	21	Ebola	Ebola	NNP
cord-256187-ofp7tupv	387	22	virus	virus	NN
cord-256187-ofp7tupv	387	23	infection	infection	NN
cord-256187-ofp7tupv	387	24	Ectodomain	Ectodomain	NNP
cord-256187-ofp7tupv	387	25	shedding	shed	VBG
cord-256187-ofp7tupv	387	26	of	of	IN
cord-256187-ofp7tupv	387	27	the	the	DT
cord-256187-ofp7tupv	387	28	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	387	29	GP	gp	NN
cord-256187-ofp7tupv	387	30	of	of	IN
cord-256187-ofp7tupv	387	31	Ebola	Ebola	NNP
cord-256187-ofp7tupv	387	32	virus	virus	NN
cord-256187-ofp7tupv	387	33	Filoviruses	Filoviruses	NNPS
cord-256187-ofp7tupv	387	34	:	:	:
cord-256187-ofp7tupv	388	1	interactions	interaction	NNS
cord-256187-ofp7tupv	388	2	with	with	IN
cord-256187-ofp7tupv	388	3	the	the	DT
cord-256187-ofp7tupv	388	4	host	host	NN
cord-256187-ofp7tupv	388	5	cell	cell	NN
cord-256187-ofp7tupv	388	6	A	a	DT
cord-256187-ofp7tupv	388	7	recombinant	recombinant	JJ
cord-256187-ofp7tupv	388	8	influenza	influenza	NN
cord-256187-ofp7tupv	388	9	A	a	DT
cord-256187-ofp7tupv	388	10	virus	virus	NN
cord-256187-ofp7tupv	388	11	expressing	express	VBG
cord-256187-ofp7tupv	388	12	an	an	DT
cord-256187-ofp7tupv	388	13	RNA	RNA	NNP
cord-256187-ofp7tupv	388	14	-	-	HYPH
cord-256187-ofp7tupv	388	15	bindingdefective	bindingdefective	NNP
cord-256187-ofp7tupv	388	16	NS1	NS1	NNP
cord-256187-ofp7tupv	388	17	protein	protein	NN
cord-256187-ofp7tupv	388	18	induces	induce	VBZ
cord-256187-ofp7tupv	388	19	high	high	JJ
cord-256187-ofp7tupv	388	20	levels	level	NNS
cord-256187-ofp7tupv	388	21	of	of	IN
cord-256187-ofp7tupv	388	22	beta	beta	NN
cord-256187-ofp7tupv	388	23	interferon	interferon	NN
cord-256187-ofp7tupv	388	24	and	and	CC
cord-256187-ofp7tupv	388	25	is	be	VBZ
cord-256187-ofp7tupv	388	26	attenuated	attenuate	VBN
cord-256187-ofp7tupv	388	27	in	in	IN
cord-256187-ofp7tupv	388	28	mice	mice	NN
cord-256187-ofp7tupv	388	29	Vpu	Vpu	NNP
cord-256187-ofp7tupv	388	30	directs	direct	VBZ
cord-256187-ofp7tupv	388	31	the	the	DT
cord-256187-ofp7tupv	388	32	degradation	degradation	NN
cord-256187-ofp7tupv	388	33	of	of	IN
cord-256187-ofp7tupv	388	34	the	the	DT
cord-256187-ofp7tupv	388	35	human	human	JJ
cord-256187-ofp7tupv	388	36	immunodeficiency	immunodeficiency	NN
cord-256187-ofp7tupv	388	37	virus	virus	NN
cord-256187-ofp7tupv	388	38	restriction	restriction	NN
cord-256187-ofp7tupv	388	39	factor	factor	NN
cord-256187-ofp7tupv	388	40	BST-2	BST-2	NNP
cord-256187-ofp7tupv	388	41	/	/	SYM
cord-256187-ofp7tupv	388	42	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	388	43	via	via	IN
cord-256187-ofp7tupv	388	44	a	a	DT
cord-256187-ofp7tupv	388	45	{	{	-LRB-
cord-256187-ofp7tupv	388	46	beta}TrCP	beta}trcp	NN
cord-256187-ofp7tupv	388	47	-	-	HYPH
cord-256187-ofp7tupv	388	48	dependent	dependent	JJ
cord-256187-ofp7tupv	388	49	mechanism	mechanism	NN
cord-256187-ofp7tupv	388	50	Antagonism	antagonism	NN
cord-256187-ofp7tupv	388	51	of	of	IN
cord-256187-ofp7tupv	388	52	tetherin	tetherin	NN
cord-256187-ofp7tupv	388	53	restriction	restriction	NN
cord-256187-ofp7tupv	388	54	of	of	IN
cord-256187-ofp7tupv	388	55	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	388	56	release	release	NN
cord-256187-ofp7tupv	388	57	by	by	IN
cord-256187-ofp7tupv	388	58	Vpu	Vpu	NNP
cord-256187-ofp7tupv	388	59	involves	involve	VBZ
cord-256187-ofp7tupv	388	60	binding	binding	NN
cord-256187-ofp7tupv	388	61	and	and	CC
cord-256187-ofp7tupv	388	62	sequestration	sequestration	NN
cord-256187-ofp7tupv	388	63	of	of	IN
cord-256187-ofp7tupv	388	64	the	the	DT
cord-256187-ofp7tupv	388	65	restriction	restriction	NN
cord-256187-ofp7tupv	388	66	factor	factor	NN
cord-256187-ofp7tupv	388	67	in	in	IN
cord-256187-ofp7tupv	388	68	a	a	DT
cord-256187-ofp7tupv	388	69	perinuclear	perinuclear	NNP
cord-256187-ofp7tupv	388	70	compartment	compartment	NN
cord-256187-ofp7tupv	388	71	Molecular	molecular	JJ
cord-256187-ofp7tupv	388	72	determinants	determinant	NNS
cord-256187-ofp7tupv	388	73	of	of	IN
cord-256187-ofp7tupv	388	74	Ebola	Ebola	NNP
cord-256187-ofp7tupv	388	75	virus	virus	NN
cord-256187-ofp7tupv	388	76	virulence	virulence	NN
cord-256187-ofp7tupv	388	77	in	in	IN
cord-256187-ofp7tupv	388	78	mice	mouse	NNS
cord-256187-ofp7tupv	389	1	VP35	VP35	NNP
cord-256187-ofp7tupv	389	2	knockdown	knockdown	NN
cord-256187-ofp7tupv	389	3	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	389	4	Ebola	Ebola	NNP
cord-256187-ofp7tupv	389	5	virus	virus	NN
cord-256187-ofp7tupv	389	6	amplification	amplification	NN
cord-256187-ofp7tupv	389	7	and	and	CC
cord-256187-ofp7tupv	389	8	protects	protect	VBZ
cord-256187-ofp7tupv	389	9	against	against	IN
cord-256187-ofp7tupv	389	10	lethal	lethal	JJ
cord-256187-ofp7tupv	389	11	infection	infection	NN
cord-256187-ofp7tupv	389	12	in	in	IN
cord-256187-ofp7tupv	389	13	mice	mouse	NNS
cord-256187-ofp7tupv	390	1	In	in	IN
cord-256187-ofp7tupv	390	2	vivo	vivo	NN
cord-256187-ofp7tupv	390	3	expression	expression	NN
cord-256187-ofp7tupv	390	4	profile	profile	NN
cord-256187-ofp7tupv	390	5	of	of	IN
cord-256187-ofp7tupv	390	6	the	the	DT
cord-256187-ofp7tupv	390	7	antiviral	antiviral	JJ
cord-256187-ofp7tupv	390	8	restriction	restriction	NN
cord-256187-ofp7tupv	390	9	factor	factor	NN
cord-256187-ofp7tupv	390	10	and	and	CC
cord-256187-ofp7tupv	390	11	tumor	tumor	NN
cord-256187-ofp7tupv	390	12	-	-	HYPH
cord-256187-ofp7tupv	390	13	targeting	target	VBG
cord-256187-ofp7tupv	390	14	antigen	antigen	NN
cord-256187-ofp7tupv	390	15	CD317	CD317	NNP
cord-256187-ofp7tupv	390	16	/	/	SYM
cord-256187-ofp7tupv	390	17	BST-2	BST-2	NNP
cord-256187-ofp7tupv	390	18	/	/	SYM
cord-256187-ofp7tupv	390	19	HM1.24	HM1.24	NNP
cord-256187-ofp7tupv	390	20	/	/	SYM
cord-256187-ofp7tupv	390	21	tetherin	tetherin	NNS
cord-256187-ofp7tupv	390	22	in	in	IN
cord-256187-ofp7tupv	390	23	humans	human	NNS
cord-256187-ofp7tupv	391	1	Ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	391	2	proteins	protein	NNS
cord-256187-ofp7tupv	391	3	suppress	suppress	VBP
cord-256187-ofp7tupv	391	4	the	the	DT
cord-256187-ofp7tupv	391	5	effects	effect	NNS
cord-256187-ofp7tupv	391	6	of	of	IN
cord-256187-ofp7tupv	391	7	small	small	JJ
cord-256187-ofp7tupv	391	8	interfering	interfere	VBG
cord-256187-ofp7tupv	391	9	RNA	RNA	NNP
cord-256187-ofp7tupv	391	10	by	by	IN
cord-256187-ofp7tupv	391	11	direct	direct	JJ
cord-256187-ofp7tupv	391	12	interaction	interaction	NN
cord-256187-ofp7tupv	391	13	with	with	IN
cord-256187-ofp7tupv	391	14	the	the	DT
cord-256187-ofp7tupv	391	15	mammalian	mammalian	JJ
cord-256187-ofp7tupv	391	16	RNA	RNA	NNP
cord-256187-ofp7tupv	391	17	interference	interference	NN
cord-256187-ofp7tupv	391	18	pathway	pathway	NN
cord-256187-ofp7tupv	392	1	The	the	DT
cord-256187-ofp7tupv	392	2	VP35	VP35	NNP
cord-256187-ofp7tupv	392	3	protein	protein	NN
cord-256187-ofp7tupv	392	4	of	of	IN
cord-256187-ofp7tupv	392	5	Ebola	Ebola	NNP
cord-256187-ofp7tupv	392	6	virus	virus	NN
cord-256187-ofp7tupv	392	7	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	392	8	the	the	DT
cord-256187-ofp7tupv	392	9	antiviral	antiviral	JJ
cord-256187-ofp7tupv	392	10	effect	effect	NN
cord-256187-ofp7tupv	392	11	mediated	mediate	VBN
cord-256187-ofp7tupv	392	12	by	by	IN
cord-256187-ofp7tupv	392	13	double	double	RB
cord-256187-ofp7tupv	392	14	-	-	HYPH
cord-256187-ofp7tupv	392	15	stranded	strand	VBN
cord-256187-ofp7tupv	392	16	RNA	rna	NN
cord-256187-ofp7tupv	392	17	-	-	HYPH
cord-256187-ofp7tupv	392	18	dependent	dependent	JJ
cord-256187-ofp7tupv	392	19	protein	protein	NN
cord-256187-ofp7tupv	392	20	kinase	kinase	VBZ
cord-256187-ofp7tupv	392	21	PKR	PKR	NNP
cord-256187-ofp7tupv	393	1	The	the	DT
cord-256187-ofp7tupv	393	2	dsRNA	dsrna	NN
cord-256187-ofp7tupv	393	3	protein	protein	NN
cord-256187-ofp7tupv	393	4	kinase	kinase	VBZ
cord-256187-ofp7tupv	393	5	PKR	PKR	NNP
cord-256187-ofp7tupv	393	6	:	:	:
cord-256187-ofp7tupv	393	7	virus	virus	NN
cord-256187-ofp7tupv	393	8	and	and	CC
cord-256187-ofp7tupv	393	9	cell	cell	NN
cord-256187-ofp7tupv	393	10	control	control	NN
cord-256187-ofp7tupv	393	11	Type	type	NN
cord-256187-ofp7tupv	393	12	1	1	CD
cord-256187-ofp7tupv	393	13	interferons	interferon	NNS
cord-256187-ofp7tupv	393	14	and	and	CC
cord-256187-ofp7tupv	393	15	the	the	DT
cord-256187-ofp7tupv	393	16	virus	virus	NN
cord-256187-ofp7tupv	393	17	-	-	HYPH
cord-256187-ofp7tupv	393	18	host	host	NN
cord-256187-ofp7tupv	393	19	relationship	relationship	NN
cord-256187-ofp7tupv	393	20	:	:	:
cord-256187-ofp7tupv	393	21	a	a	DT
cord-256187-ofp7tupv	393	22	lesson	lesson	NN
cord-256187-ofp7tupv	393	23	in	in	IN
cord-256187-ofp7tupv	393	24	detente	detente	NN
cord-256187-ofp7tupv	393	25	Tipping	tip	VBG
cord-256187-ofp7tupv	393	26	the	the	DT
cord-256187-ofp7tupv	393	27	balance	balance	NN
cord-256187-ofp7tupv	393	28	:	:	:
cord-256187-ofp7tupv	393	29	antagonism	antagonism	NN
cord-256187-ofp7tupv	393	30	of	of	IN
cord-256187-ofp7tupv	393	31	PKR	PKR	NNP
cord-256187-ofp7tupv	393	32	kinase	kinase	NN
cord-256187-ofp7tupv	393	33	and	and	CC
cord-256187-ofp7tupv	393	34	ADAR1	adar1	NN
cord-256187-ofp7tupv	393	35	deaminase	deaminase	NN
cord-256187-ofp7tupv	393	36	functions	function	NNS
cord-256187-ofp7tupv	393	37	by	by	IN
cord-256187-ofp7tupv	393	38	virus	virus	NN
cord-256187-ofp7tupv	393	39	gene	gene	NN
cord-256187-ofp7tupv	393	40	products	product	VBZ
cord-256187-ofp7tupv	393	41	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	393	42	antagonism	antagonism	NN
cord-256187-ofp7tupv	393	43	of	of	IN
cord-256187-ofp7tupv	393	44	CD317	CD317	NNP
cord-256187-ofp7tupv	393	45	is	be	VBZ
cord-256187-ofp7tupv	393	46	species	specie	NNS
cord-256187-ofp7tupv	393	47	specific	specific	JJ
cord-256187-ofp7tupv	393	48	and	and	CC
cord-256187-ofp7tupv	393	49	involves	involve	VBZ
cord-256187-ofp7tupv	393	50	Vpu	Vpu	NNP
cord-256187-ofp7tupv	393	51	-	-	HYPH
cord-256187-ofp7tupv	393	52	mediated	mediate	VBN
cord-256187-ofp7tupv	393	53	proteasomal	proteasomal	JJ
cord-256187-ofp7tupv	393	54	degradation	degradation	NN
cord-256187-ofp7tupv	393	55	of	of	IN
cord-256187-ofp7tupv	393	56	the	the	DT
cord-256187-ofp7tupv	393	57	restriction	restriction	NN
cord-256187-ofp7tupv	393	58	factor	factor	NN
cord-256187-ofp7tupv	393	59	Antagonism	antagonism	NN
cord-256187-ofp7tupv	393	60	of	of	IN
cord-256187-ofp7tupv	393	61	CD317	CD317	NNP
cord-256187-ofp7tupv	393	62	restriction	restriction	NN
cord-256187-ofp7tupv	393	63	of	of	IN
cord-256187-ofp7tupv	393	64	human	human	JJ
cord-256187-ofp7tupv	393	65	immunodeficiency	immunodeficiency	NN
cord-256187-ofp7tupv	393	66	virus	virus	NN
cord-256187-ofp7tupv	393	67	type	type	NN
cord-256187-ofp7tupv	393	68	1	1	CD
cord-256187-ofp7tupv	393	69	(	(	-LRB-
cord-256187-ofp7tupv	393	70	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	393	71	)	)	-RRB-
cord-256187-ofp7tupv	393	72	particle	particle	NN
cord-256187-ofp7tupv	393	73	release	release	NN
cord-256187-ofp7tupv	393	74	and	and	CC
cord-256187-ofp7tupv	393	75	depletion	depletion	NN
cord-256187-ofp7tupv	393	76	of	of	IN
cord-256187-ofp7tupv	393	77	CD317	CD317	NNPS
cord-256187-ofp7tupv	393	78	are	be	VBP
cord-256187-ofp7tupv	393	79	separable	separable	JJ
cord-256187-ofp7tupv	393	80	activities	activity	NNS
cord-256187-ofp7tupv	393	81	of	of	IN
cord-256187-ofp7tupv	394	1	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	394	2	Vpu	Vpu	NNP
cord-256187-ofp7tupv	394	3	The	the	DT
cord-256187-ofp7tupv	394	4	ecology	ecology	NN
cord-256187-ofp7tupv	394	5	of	of	IN
cord-256187-ofp7tupv	394	6	Ebola	Ebola	NNP
cord-256187-ofp7tupv	394	7	virus	virus	NN
cord-256187-ofp7tupv	394	8	Simian	simian	JJ
cord-256187-ofp7tupv	394	9	immunodeficiency	immunodeficiency	NN
cord-256187-ofp7tupv	394	10	virus	virus	NN
cord-256187-ofp7tupv	394	11	envelope	envelope	NN
cord-256187-ofp7tupv	394	12	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	394	13	counteracts	counteract	VBZ
cord-256187-ofp7tupv	394	14	tetherin	tetherin	NNP
cord-256187-ofp7tupv	394	15	/	/	SYM
cord-256187-ofp7tupv	394	16	BST-2	BST-2	NNP
cord-256187-ofp7tupv	394	17	/	/	SYM
cord-256187-ofp7tupv	394	18	CD317	CD317	NNP
cord-256187-ofp7tupv	394	19	by	by	IN
cord-256187-ofp7tupv	394	20	intracellular	intracellular	JJ
cord-256187-ofp7tupv	394	21	sequestration	sequestration	NN
cord-256187-ofp7tupv	395	1	The	the	DT
cord-256187-ofp7tupv	395	2	Ebola	Ebola	NNP
cord-256187-ofp7tupv	395	3	virus	virus	NN
cord-256187-ofp7tupv	395	4	VP35	VP35	NNP
cord-256187-ofp7tupv	395	5	protein	protein	NN
cord-256187-ofp7tupv	395	6	is	be	VBZ
cord-256187-ofp7tupv	395	7	a	a	DT
cord-256187-ofp7tupv	395	8	suppressor	suppressor	NN
cord-256187-ofp7tupv	395	9	of	of	IN
cord-256187-ofp7tupv	395	10	RNA	RNA	NNP
cord-256187-ofp7tupv	395	11	silencing	silence	VBG
cord-256187-ofp7tupv	395	12	Interferoninduced	Interferoninduced	NNP
cord-256187-ofp7tupv	395	13	Mx	Mx	NNP
cord-256187-ofp7tupv	395	14	proteins	protein	NNS
cord-256187-ofp7tupv	395	15	in	in	IN
cord-256187-ofp7tupv	395	16	antiviral	antiviral	JJ
cord-256187-ofp7tupv	395	17	host	host	NN
cord-256187-ofp7tupv	395	18	defense	defense	NN
cord-256187-ofp7tupv	395	19	Immunoelectron	Immunoelectron	NNP
cord-256187-ofp7tupv	395	20	microscopic	microscopic	JJ
cord-256187-ofp7tupv	395	21	evidence	evidence	NN
cord-256187-ofp7tupv	395	22	for	for	IN
cord-256187-ofp7tupv	395	23	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	395	24	/	/	SYM
cord-256187-ofp7tupv	395	25	BST2	BST2	NNP
cord-256187-ofp7tupv	395	26	as	as	IN
cord-256187-ofp7tupv	395	27	the	the	DT
cord-256187-ofp7tupv	395	28	physical	physical	JJ
cord-256187-ofp7tupv	395	29	bridge	bridge	NN
cord-256187-ofp7tupv	395	30	between	between	IN
cord-256187-ofp7tupv	395	31	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	395	32	virions	virion	NNS
cord-256187-ofp7tupv	395	33	and	and	CC
cord-256187-ofp7tupv	395	34	the	the	DT
cord-256187-ofp7tupv	395	35	plasma	plasma	NN
cord-256187-ofp7tupv	395	36	membrane	membrane	NN
cord-256187-ofp7tupv	395	37	Biochemical	biochemical	JJ
cord-256187-ofp7tupv	395	38	and	and	CC
cord-256187-ofp7tupv	395	39	functional	functional	JJ
cord-256187-ofp7tupv	395	40	characterization	characterization	NN
cord-256187-ofp7tupv	395	41	of	of	IN
cord-256187-ofp7tupv	395	42	the	the	DT
cord-256187-ofp7tupv	395	43	Ebola	Ebola	NNP
cord-256187-ofp7tupv	395	44	virus	virus	NN
cord-256187-ofp7tupv	395	45	VP24	VP24	NNP
cord-256187-ofp7tupv	395	46	protein	protein	NN
cord-256187-ofp7tupv	395	47	:	:	:
cord-256187-ofp7tupv	395	48	implications	implication	NNS
cord-256187-ofp7tupv	395	49	for	for	IN
cord-256187-ofp7tupv	395	50	a	a	DT
cord-256187-ofp7tupv	395	51	role	role	NN
cord-256187-ofp7tupv	395	52	in	in	IN
cord-256187-ofp7tupv	395	53	virus	virus	NN
cord-256187-ofp7tupv	395	54	assembly	assembly	NN
cord-256187-ofp7tupv	395	55	and	and	CC
cord-256187-ofp7tupv	395	56	budding	bud	VBG
cord-256187-ofp7tupv	395	57	Filovirus	Filovirus	NNP
cord-256187-ofp7tupv	395	58	assembly	assembly	NN
cord-256187-ofp7tupv	395	59	and	and	CC
cord-256187-ofp7tupv	395	60	budding	bud	VBG
cord-256187-ofp7tupv	395	61	A	a	DT
cord-256187-ofp7tupv	395	62	C	c	NN
cord-256187-ofp7tupv	395	63	-	-	HYPH
cord-256187-ofp7tupv	395	64	terminal	terminal	JJ
cord-256187-ofp7tupv	395	65	basic	basic	JJ
cord-256187-ofp7tupv	395	66	amino	amino	NN
cord-256187-ofp7tupv	395	67	acid	acid	NN
cord-256187-ofp7tupv	395	68	motif	motif	NN
cord-256187-ofp7tupv	395	69	of	of	IN
cord-256187-ofp7tupv	395	70	Zaire	Zaire	NNP
cord-256187-ofp7tupv	395	71	ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	395	72	VP35	VP35	NNP
cord-256187-ofp7tupv	395	73	is	be	VBZ
cord-256187-ofp7tupv	395	74	essential	essential	JJ
cord-256187-ofp7tupv	395	75	for	for	IN
cord-256187-ofp7tupv	395	76	type	type	NN
cord-256187-ofp7tupv	396	1	I	-PRON-	PRP
cord-256187-ofp7tupv	396	2	interferon	interferon	VBD
cord-256187-ofp7tupv	396	3	antagonism	antagonism	NN
cord-256187-ofp7tupv	396	4	and	and	CC
cord-256187-ofp7tupv	396	5	displays	display	VBZ
cord-256187-ofp7tupv	396	6	high	high	JJ
cord-256187-ofp7tupv	396	7	identity	identity	NN
cord-256187-ofp7tupv	396	8	with	with	IN
cord-256187-ofp7tupv	396	9	the	the	DT
cord-256187-ofp7tupv	396	10	RNA	RNA	NNP
cord-256187-ofp7tupv	396	11	-	-	HYPH
cord-256187-ofp7tupv	396	12	binding	bind	VBG
cord-256187-ofp7tupv	396	13	domain	domain	NN
cord-256187-ofp7tupv	396	14	of	of	IN
cord-256187-ofp7tupv	396	15	another	another	DT
cord-256187-ofp7tupv	396	16	interferon	interferon	NN
cord-256187-ofp7tupv	396	17	antagonist	antagonist	NN
cord-256187-ofp7tupv	396	18	,	,	,
cord-256187-ofp7tupv	397	1	the	the	DT
cord-256187-ofp7tupv	397	2	NS1	NS1	NNP
cord-256187-ofp7tupv	397	3	protein	protein	NN
cord-256187-ofp7tupv	397	4	of	of	IN
cord-256187-ofp7tupv	397	5	influenza	influenza	NN
cord-256187-ofp7tupv	397	6	A	a	DT
cord-256187-ofp7tupv	397	7	virus	virus	NN
cord-256187-ofp7tupv	397	8	Reverse	reverse	VB
cord-256187-ofp7tupv	397	9	genetic	genetic	JJ
cord-256187-ofp7tupv	397	10	generation	generation	NN
cord-256187-ofp7tupv	397	11	of	of	IN
cord-256187-ofp7tupv	397	12	recombinant	recombinant	JJ
cord-256187-ofp7tupv	397	13	Zaire	Zaire	NNP
cord-256187-ofp7tupv	397	14	Ebola	Ebola	NNP
cord-256187-ofp7tupv	397	15	viruses	virus	NNS
cord-256187-ofp7tupv	397	16	containing	contain	VBG
cord-256187-ofp7tupv	397	17	disrupted	disrupt	VBD
cord-256187-ofp7tupv	397	18	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	397	19	inhibitory	inhibitory	JJ
cord-256187-ofp7tupv	397	20	domains	domain	NNS
cord-256187-ofp7tupv	397	21	results	result	NNS
cord-256187-ofp7tupv	397	22	in	in	IN
cord-256187-ofp7tupv	397	23	attenuated	attenuated	JJ
cord-256187-ofp7tupv	397	24	virus	virus	NN
cord-256187-ofp7tupv	397	25	growth	growth	NN
cord-256187-ofp7tupv	397	26	in	in	IN
cord-256187-ofp7tupv	397	27	vitro	vitro	FW
cord-256187-ofp7tupv	397	28	and	and	CC
cord-256187-ofp7tupv	397	29	higher	high	JJR
cord-256187-ofp7tupv	397	30	levels	level	NNS
cord-256187-ofp7tupv	397	31	of	of	IN
cord-256187-ofp7tupv	397	32	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	397	33	activation	activation	NN
cord-256187-ofp7tupv	397	34	without	without	IN
cord-256187-ofp7tupv	397	35	inhibiting	inhibit	VBG
cord-256187-ofp7tupv	397	36	viral	viral	JJ
cord-256187-ofp7tupv	397	37	transcription	transcription	NN
cord-256187-ofp7tupv	397	38	or	or	CC
cord-256187-ofp7tupv	397	39	replication	replication	NN
cord-256187-ofp7tupv	397	40	Inhibition	inhibition	NN
cord-256187-ofp7tupv	397	41	of	of	IN
cord-256187-ofp7tupv	397	42	IRF-3	IRF-3	NNP
cord-256187-ofp7tupv	397	43	activation	activation	NN
cord-256187-ofp7tupv	397	44	by	by	IN
cord-256187-ofp7tupv	397	45	VP35	VP35	NNP
cord-256187-ofp7tupv	397	46	is	be	VBZ
cord-256187-ofp7tupv	397	47	critical	critical	JJ
cord-256187-ofp7tupv	397	48	for	for	IN
cord-256187-ofp7tupv	397	49	the	the	DT
cord-256187-ofp7tupv	397	50	high	high	JJ
cord-256187-ofp7tupv	397	51	level	level	NN
cord-256187-ofp7tupv	397	52	of	of	IN
cord-256187-ofp7tupv	397	53	virulence	virulence	NN
cord-256187-ofp7tupv	397	54	of	of	IN
cord-256187-ofp7tupv	397	55	Ebola	Ebola	NNP
cord-256187-ofp7tupv	397	56	virus	virus	NN
cord-256187-ofp7tupv	397	57	Whole	whole	JJ
cord-256187-ofp7tupv	397	58	-	-	HYPH
cord-256187-ofp7tupv	397	59	genome	genome	NN
cord-256187-ofp7tupv	397	60	expression	expression	NN
cord-256187-ofp7tupv	397	61	profiling	profiling	NN
cord-256187-ofp7tupv	397	62	reveals	reveal	VBZ
cord-256187-ofp7tupv	397	63	that	that	IN
cord-256187-ofp7tupv	397	64	inhibition	inhibition	NN
cord-256187-ofp7tupv	397	65	of	of	IN
cord-256187-ofp7tupv	397	66	host	host	NN
cord-256187-ofp7tupv	397	67	innate	innate	JJ
cord-256187-ofp7tupv	397	68	immune	immune	JJ
cord-256187-ofp7tupv	397	69	response	response	NN
cord-256187-ofp7tupv	397	70	pathways	pathway	NNS
cord-256187-ofp7tupv	397	71	by	by	IN
cord-256187-ofp7tupv	397	72	Ebola	Ebola	NNP
cord-256187-ofp7tupv	397	73	virus	virus	NN
cord-256187-ofp7tupv	397	74	can	can	MD
cord-256187-ofp7tupv	397	75	be	be	VB
cord-256187-ofp7tupv	397	76	reversed	reverse	VBN
cord-256187-ofp7tupv	397	77	by	by	IN
cord-256187-ofp7tupv	397	78	a	a	DT
cord-256187-ofp7tupv	397	79	single	single	JJ
cord-256187-ofp7tupv	397	80	amino	amino	NN
cord-256187-ofp7tupv	397	81	acid	acid	NN
cord-256187-ofp7tupv	397	82	change	change	NN
cord-256187-ofp7tupv	397	83	in	in	IN
cord-256187-ofp7tupv	397	84	the	the	DT
cord-256187-ofp7tupv	397	85	VP35	VP35	NNP
cord-256187-ofp7tupv	397	86	protein	protein	NN
cord-256187-ofp7tupv	397	87	Ebola	Ebola	NNP
cord-256187-ofp7tupv	397	88	and	and	CC
cord-256187-ofp7tupv	397	89	marburg	marburg	NNP
cord-256187-ofp7tupv	397	90	hemorrhagic	hemorrhagic	JJ
cord-256187-ofp7tupv	397	91	fever	fever	NN
cord-256187-ofp7tupv	397	92	Long	long	JJ
cord-256187-ofp7tupv	397	93	-	-	HYPH
cord-256187-ofp7tupv	397	94	term	term	NN
cord-256187-ofp7tupv	397	95	survival	survival	NN
cord-256187-ofp7tupv	397	96	of	of	IN
cord-256187-ofp7tupv	397	97	an	an	DT
cord-256187-ofp7tupv	397	98	urban	urban	JJ
cord-256187-ofp7tupv	397	99	fruit	fruit	NN
cord-256187-ofp7tupv	397	100	bat	bat	NN
cord-256187-ofp7tupv	397	101	seropositive	seropositive	JJ
cord-256187-ofp7tupv	397	102	for	for	IN
cord-256187-ofp7tupv	397	103	Ebola	Ebola	NNP
cord-256187-ofp7tupv	397	104	and	and	CC
cord-256187-ofp7tupv	397	105	Lagos	Lagos	NNP
cord-256187-ofp7tupv	397	106	bat	bat	NN
cord-256187-ofp7tupv	397	107	viruses	viruse	VBZ
cord-256187-ofp7tupv	397	108	Infection	infection	NN
cord-256187-ofp7tupv	397	109	of	of	IN
cord-256187-ofp7tupv	397	110	naive	naive	JJ
cord-256187-ofp7tupv	397	111	target	target	NN
cord-256187-ofp7tupv	397	112	cells	cell	NNS
cord-256187-ofp7tupv	397	113	with	with	IN
cord-256187-ofp7tupv	397	114	virus	virus	NN
cord-256187-ofp7tupv	397	115	-	-	HYPH
cord-256187-ofp7tupv	397	116	like	like	JJ
cord-256187-ofp7tupv	397	117	particles	particle	NNS
cord-256187-ofp7tupv	397	118	:	:	:
cord-256187-ofp7tupv	397	119	implications	implication	NNS
cord-256187-ofp7tupv	397	120	for	for	IN
cord-256187-ofp7tupv	397	121	the	the	DT
cord-256187-ofp7tupv	397	122	function	function	NN
cord-256187-ofp7tupv	397	123	of	of	IN
cord-256187-ofp7tupv	397	124	Ebola	Ebola	NNP
cord-256187-ofp7tupv	397	125	virus	virus	NN
cord-256187-ofp7tupv	398	1	VP24	VP24	NNP
cord-256187-ofp7tupv	398	2	IRF-7	IRF-7	NNP
cord-256187-ofp7tupv	398	3	is	be	VBZ
cord-256187-ofp7tupv	398	4	the	the	DT
cord-256187-ofp7tupv	398	5	master	master	NN
cord-256187-ofp7tupv	398	6	regulator	regulator	NN
cord-256187-ofp7tupv	398	7	of	of	IN
cord-256187-ofp7tupv	398	8	type-	type-	NNP
cord-256187-ofp7tupv	399	1	I	-PRON-	PRP
cord-256187-ofp7tupv	399	2	interferon	interferon	NN
cord-256187-ofp7tupv	399	3	-	-	HYPH
cord-256187-ofp7tupv	399	4	dependent	dependent	JJ
cord-256187-ofp7tupv	399	5	immune	immune	JJ
cord-256187-ofp7tupv	399	6	responses	response	NNS
cord-256187-ofp7tupv	400	1	The	the	DT
cord-256187-ofp7tupv	400	2	assembly	assembly	NN
cord-256187-ofp7tupv	400	3	of	of	IN
cord-256187-ofp7tupv	400	4	Ebola	Ebola	NNP
cord-256187-ofp7tupv	400	5	virus	virus	NN
cord-256187-ofp7tupv	400	6	nucleocapsid	nucleocapsid	NN
cord-256187-ofp7tupv	400	7	requires	require	VBZ
cord-256187-ofp7tupv	400	8	virion	virion	NN
cord-256187-ofp7tupv	400	9	-	-	HYPH
cord-256187-ofp7tupv	400	10	associated	associate	VBN
cord-256187-ofp7tupv	400	11	proteins	protein	NNS
cord-256187-ofp7tupv	400	12	35	35	CD
cord-256187-ofp7tupv	400	13	and	and	CC
cord-256187-ofp7tupv	400	14	24	24	CD
cord-256187-ofp7tupv	400	15	and	and	CC
cord-256187-ofp7tupv	400	16	posttranslational	posttranslational	JJ
cord-256187-ofp7tupv	400	17	modification	modification	NN
cord-256187-ofp7tupv	400	18	of	of	IN
cord-256187-ofp7tupv	400	19	nucleoprotein	nucleoprotein	JJ
cord-256187-ofp7tupv	400	20	Distinct	distinct	JJ
cord-256187-ofp7tupv	400	21	patterns	pattern	NNS
cord-256187-ofp7tupv	400	22	of	of	IN
cord-256187-ofp7tupv	400	23	IFITM	ifitm	NN
cord-256187-ofp7tupv	400	24	-	-	HYPH
cord-256187-ofp7tupv	400	25	mediated	mediate	VBN
cord-256187-ofp7tupv	400	26	restriction	restriction	NN
cord-256187-ofp7tupv	400	27	of	of	IN
cord-256187-ofp7tupv	400	28	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	400	29	,	,	,
cord-256187-ofp7tupv	400	30	SARS	SARS	NNP
cord-256187-ofp7tupv	400	31	coronavirus	coronavirus	NN
cord-256187-ofp7tupv	400	32	,	,	,
cord-256187-ofp7tupv	400	33	and	and	CC
cord-256187-ofp7tupv	400	34	influenza	influenza	NN
cord-256187-ofp7tupv	400	35	A	a	DT
cord-256187-ofp7tupv	400	36	virus	virus	NN
cord-256187-ofp7tupv	400	37	.	.	.
cord-256187-ofp7tupv	401	1	PLoS	PLoS	NNP
cord-256187-ofp7tupv	401	2	Pathog	Pathog	NNP
cord-256187-ofp7tupv	401	3	Species	species	NN
cord-256187-ofp7tupv	401	4	-	-	HYPH
cord-256187-ofp7tupv	401	5	specific	specific	JJ
cord-256187-ofp7tupv	401	6	activity	activity	NN
cord-256187-ofp7tupv	401	7	of	of	IN
cord-256187-ofp7tupv	401	8	SIV	SIV	NNP
cord-256187-ofp7tupv	401	9	Nef	Nef	NNP
cord-256187-ofp7tupv	401	10	and	and	CC
cord-256187-ofp7tupv	401	11	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	401	12	Vpu	Vpu	NNP
cord-256187-ofp7tupv	401	13	in	in	IN
cord-256187-ofp7tupv	401	14	overcoming	overcome	VBG
cord-256187-ofp7tupv	401	15	restriction	restriction	NN
cord-256187-ofp7tupv	401	16	by	by	IN
cord-256187-ofp7tupv	401	17	tetherin	tetherin	NNP
cord-256187-ofp7tupv	401	18	/	/	SYM
cord-256187-ofp7tupv	401	19	BST2	BST2	NNP
cord-256187-ofp7tupv	401	20	Identification	Identification	NNP
cord-256187-ofp7tupv	401	21	of	of	IN
cord-256187-ofp7tupv	401	22	five	five	CD
cord-256187-ofp7tupv	401	23	interferon	interferon	NN
cord-256187-ofp7tupv	401	24	-	-	HYPH
cord-256187-ofp7tupv	401	25	induced	induce	VBN
cord-256187-ofp7tupv	401	26	cellular	cellular	JJ
cord-256187-ofp7tupv	401	27	proteins	protein	NNS
cord-256187-ofp7tupv	401	28	that	that	WDT
cord-256187-ofp7tupv	401	29	inhibit	inhibit	VBP
cord-256187-ofp7tupv	401	30	west	west	NNP
cord-256187-ofp7tupv	401	31	nile	nile	NNP
cord-256187-ofp7tupv	401	32	virus	virus	NN
cord-256187-ofp7tupv	401	33	and	and	CC
cord-256187-ofp7tupv	401	34	dengue	dengue	NN
cord-256187-ofp7tupv	401	35	virus	virus	NN
cord-256187-ofp7tupv	401	36	infections	infection	NNS
cord-256187-ofp7tupv	402	1	The	the	DT
cord-256187-ofp7tupv	402	2	VP35	VP35	NNP
cord-256187-ofp7tupv	402	3	protein	protein	NN
cord-256187-ofp7tupv	402	4	of	of	IN
cord-256187-ofp7tupv	402	5	Ebola	Ebola	NNP
cord-256187-ofp7tupv	402	6	virus	virus	NN
cord-256187-ofp7tupv	402	7	impairs	impair	VBZ
cord-256187-ofp7tupv	402	8	dendritic	dendritic	JJ
cord-256187-ofp7tupv	402	9	cell	cell	NN
cord-256187-ofp7tupv	402	10	maturation	maturation	NN
cord-256187-ofp7tupv	402	11	induced	induce	VBN
cord-256187-ofp7tupv	402	12	by	by	IN
cord-256187-ofp7tupv	402	13	virus	virus	NN
cord-256187-ofp7tupv	402	14	and	and	CC
cord-256187-ofp7tupv	402	15	lipopolysaccharide	lipopolysaccharide	NN
cord-256187-ofp7tupv	402	16	Broad	Broad	NNP
cord-256187-ofp7tupv	402	17	-	-	HYPH
cord-256187-ofp7tupv	402	18	spectrum	spectrum	NN
cord-256187-ofp7tupv	402	19	inhibition	inhibition	NN
cord-256187-ofp7tupv	402	20	of	of	IN
cord-256187-ofp7tupv	402	21	retroviral	retroviral	JJ
cord-256187-ofp7tupv	402	22	and	and	CC
cord-256187-ofp7tupv	402	23	filoviral	filoviral	JJ
cord-256187-ofp7tupv	402	24	particle	particle	NN
cord-256187-ofp7tupv	402	25	release	release	NN
cord-256187-ofp7tupv	402	26	by	by	IN
cord-256187-ofp7tupv	402	27	tetherin	tetherin	NNP
cord-256187-ofp7tupv	402	28	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	402	29	-	-	HYPH
cord-256187-ofp7tupv	402	30	mediated	mediate	VBN
cord-256187-ofp7tupv	402	31	restriction	restriction	NN
cord-256187-ofp7tupv	402	32	of	of	IN
cord-256187-ofp7tupv	402	33	filovirus	filovirus	NN
cord-256187-ofp7tupv	402	34	budding	budding	NN
cord-256187-ofp7tupv	402	35	is	be	VBZ
cord-256187-ofp7tupv	402	36	antagonized	antagonize	VBN
cord-256187-ofp7tupv	402	37	by	by	IN
cord-256187-ofp7tupv	402	38	the	the	DT
cord-256187-ofp7tupv	402	39	Ebola	Ebola	NNP
cord-256187-ofp7tupv	402	40	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	402	41	How	how	WRB
cord-256187-ofp7tupv	402	42	Ebola	Ebola	NNP
cord-256187-ofp7tupv	402	43	virus	virus	NN
cord-256187-ofp7tupv	402	44	infects	infect	VBZ
cord-256187-ofp7tupv	402	45	cells	cell	NNS
cord-256187-ofp7tupv	403	1	Ebolavirus	Ebolavirus	NNP
cord-256187-ofp7tupv	403	2	VP35	VP35	NNP
cord-256187-ofp7tupv	403	3	uses	use	VBZ
cord-256187-ofp7tupv	403	4	a	a	DT
cord-256187-ofp7tupv	403	5	bimodal	bimodal	JJ
cord-256187-ofp7tupv	403	6	strategy	strategy	NN
cord-256187-ofp7tupv	403	7	to	to	TO
cord-256187-ofp7tupv	403	8	bind	bind	VB
cord-256187-ofp7tupv	403	9	dsRNA	dsrna	JJ
cord-256187-ofp7tupv	403	10	for	for	IN
cord-256187-ofp7tupv	403	11	innate	innate	JJ
cord-256187-ofp7tupv	403	12	immune	immune	JJ
cord-256187-ofp7tupv	403	13	suppression	suppression	NN
cord-256187-ofp7tupv	404	1	The	the	DT
cord-256187-ofp7tupv	404	2	Ebola	Ebola	NNP
cord-256187-ofp7tupv	404	3	virus	virus	NN
cord-256187-ofp7tupv	404	4	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	404	5	and	and	CC
cord-256187-ofp7tupv	404	6	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	404	7	Vpu	Vpu	NNP
cord-256187-ofp7tupv	404	8	employ	employ	VBP
cord-256187-ofp7tupv	404	9	different	different	JJ
cord-256187-ofp7tupv	404	10	strategies	strategy	NNS
cord-256187-ofp7tupv	404	11	to	to	TO
cord-256187-ofp7tupv	404	12	counteract	counteract	VB
cord-256187-ofp7tupv	404	13	the	the	DT
cord-256187-ofp7tupv	404	14	antiviral	antiviral	JJ
cord-256187-ofp7tupv	404	15	factor	factor	NN
cord-256187-ofp7tupv	404	16	tetherin	tetherin	NNP
cord-256187-ofp7tupv	404	17	Comparative	Comparative	NNP
cord-256187-ofp7tupv	404	18	analysis	analysis	NN
cord-256187-ofp7tupv	404	19	of	of	IN
cord-256187-ofp7tupv	404	20	Ebola	Ebola	NNP
cord-256187-ofp7tupv	404	21	virus	virus	NN
cord-256187-ofp7tupv	404	22	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	404	23	interactions	interaction	NNS
cord-256187-ofp7tupv	404	24	with	with	IN
cord-256187-ofp7tupv	404	25	human	human	NN
cord-256187-ofp7tupv	404	26	and	and	CC
cord-256187-ofp7tupv	404	27	bat	bat	NN
cord-256187-ofp7tupv	404	28	cells	cell	NNS
cord-256187-ofp7tupv	404	29	Filoviruses	Filoviruses	NNPS
cord-256187-ofp7tupv	404	30	.	.	.
cord-256187-ofp7tupv	405	1	A	a	DT
cord-256187-ofp7tupv	405	2	compendium	compendium	NN
cord-256187-ofp7tupv	405	3	of	of	IN
cord-256187-ofp7tupv	405	4	40	40	CD
cord-256187-ofp7tupv	405	5	years	year	NNS
cord-256187-ofp7tupv	405	6	of	of	IN
cord-256187-ofp7tupv	405	7	epidemiological	epidemiological	JJ
cord-256187-ofp7tupv	405	8	,	,	,
cord-256187-ofp7tupv	405	9	clinical	clinical	JJ
cord-256187-ofp7tupv	405	10	,	,	,
cord-256187-ofp7tupv	405	11	and	and	CC
cord-256187-ofp7tupv	405	12	laboratory	laboratory	NN
cord-256187-ofp7tupv	405	13	studies	study	NNS
cord-256187-ofp7tupv	405	14	Bst-2	Bst-2	NNP
cord-256187-ofp7tupv	405	15	/	/	SYM
cord-256187-ofp7tupv	405	16	HM1.24	HM1.24	NNP
cord-256187-ofp7tupv	405	17	is	be	VBZ
cord-256187-ofp7tupv	405	18	a	a	DT
cord-256187-ofp7tupv	405	19	raft	raft	NN
cord-256187-ofp7tupv	405	20	-	-	HYPH
cord-256187-ofp7tupv	405	21	associated	associate	VBN
cord-256187-ofp7tupv	405	22	apical	apical	JJ
cord-256187-ofp7tupv	405	23	membrane	membrane	NN
cord-256187-ofp7tupv	405	24	protein	protein	NN
cord-256187-ofp7tupv	405	25	with	with	IN
cord-256187-ofp7tupv	405	26	an	an	DT
cord-256187-ofp7tupv	405	27	unusual	unusual	JJ
cord-256187-ofp7tupv	405	28	topology	topology	NN
cord-256187-ofp7tupv	405	29	Antagonism	antagonism	NN
cord-256187-ofp7tupv	405	30	to	to	IN
cord-256187-ofp7tupv	405	31	and	and	CC
cord-256187-ofp7tupv	405	32	intracellular	intracellular	JJ
cord-256187-ofp7tupv	405	33	sequestration	sequestration	NN
cord-256187-ofp7tupv	405	34	of	of	IN
cord-256187-ofp7tupv	405	35	human	human	JJ
cord-256187-ofp7tupv	405	36	tetherin	tetherin	NNS
cord-256187-ofp7tupv	405	37	by	by	IN
cord-256187-ofp7tupv	405	38	the	the	DT
cord-256187-ofp7tupv	405	39	human	human	JJ
cord-256187-ofp7tupv	405	40	immunodeficiency	immunodeficiency	NN
cord-256187-ofp7tupv	405	41	virus	virus	NN
cord-256187-ofp7tupv	405	42	type	type	NN
cord-256187-ofp7tupv	405	43	2	2	CD
cord-256187-ofp7tupv	405	44	envelope	envelope	NN
cord-256187-ofp7tupv	405	45	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	405	46	Fold	fold	JJ
cord-256187-ofp7tupv	405	47	prediction	prediction	NN
cord-256187-ofp7tupv	405	48	of	of	IN
cord-256187-ofp7tupv	405	49	VP24	VP24	NNP
cord-256187-ofp7tupv	405	50	protein	protein	NN
cord-256187-ofp7tupv	405	51	of	of	IN
cord-256187-ofp7tupv	405	52	Ebola	Ebola	NNP
cord-256187-ofp7tupv	405	53	and	and	CC
cord-256187-ofp7tupv	405	54	Marburg	Marburg	NNP
cord-256187-ofp7tupv	405	55	viruses	virus	NNS
cord-256187-ofp7tupv	405	56	using	use	VBG
cord-256187-ofp7tupv	405	57	de	de	FW
cord-256187-ofp7tupv	405	58	novo	novo	NNP
cord-256187-ofp7tupv	405	59	fragment	fragment	NNP
cord-256187-ofp7tupv	405	60	assembly	assembly	NNP
cord-256187-ofp7tupv	405	61	Fruit	Fruit	NNP
cord-256187-ofp7tupv	405	62	bats	bat	NNS
cord-256187-ofp7tupv	405	63	as	as	IN
cord-256187-ofp7tupv	405	64	reservoirs	reservoir	NNS
cord-256187-ofp7tupv	405	65	of	of	IN
cord-256187-ofp7tupv	405	66	Ebola	Ebola	NNP
cord-256187-ofp7tupv	405	67	virus	virus	NN
cord-256187-ofp7tupv	405	68	Structure	structure	NN
cord-256187-ofp7tupv	405	69	of	of	IN
cord-256187-ofp7tupv	405	70	the	the	DT
cord-256187-ofp7tupv	405	71	Ebola	Ebola	NNP
cord-256187-ofp7tupv	405	72	VP35	VP35	NNP
cord-256187-ofp7tupv	405	73	interferon	interferon	NN
cord-256187-ofp7tupv	405	74	inhibitory	inhibitory	JJ
cord-256187-ofp7tupv	405	75	domain	domain	NN
cord-256187-ofp7tupv	405	76	Structural	structural	JJ
cord-256187-ofp7tupv	405	77	basis	basis	NN
cord-256187-ofp7tupv	405	78	for	for	IN
cord-256187-ofp7tupv	405	79	dsRNA	dsrna	NN
cord-256187-ofp7tupv	405	80	recognition	recognition	NN
cord-256187-ofp7tupv	405	81	and	and	CC
cord-256187-ofp7tupv	405	82	interferon	interferon	NN
cord-256187-ofp7tupv	405	83	antagonism	antagonism	NN
cord-256187-ofp7tupv	405	84	by	by	IN
cord-256187-ofp7tupv	405	85	Ebola	Ebola	NNP
cord-256187-ofp7tupv	405	86	VP35	VP35	NNP
cord-256187-ofp7tupv	405	87	Contribution	Contribution	NNP
cord-256187-ofp7tupv	405	88	of	of	IN
cord-256187-ofp7tupv	405	89	Ebola	Ebola	NNP
cord-256187-ofp7tupv	405	90	virus	virus	NN
cord-256187-ofp7tupv	405	91	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	405	92	,	,	,
cord-256187-ofp7tupv	405	93	nucleoprotein	nucleoprotein	NNP
cord-256187-ofp7tupv	405	94	,	,	,
cord-256187-ofp7tupv	405	95	and	and	CC
cord-256187-ofp7tupv	405	96	VP24	VP24	NNP
cord-256187-ofp7tupv	405	97	to	to	IN
cord-256187-ofp7tupv	405	98	budding	bud	VBG
cord-256187-ofp7tupv	405	99	of	of	IN
cord-256187-ofp7tupv	405	100	VP40	VP40	NNP
cord-256187-ofp7tupv	405	101	virus	virus	NN
cord-256187-ofp7tupv	405	102	-	-	:
cord-256187-ofp7tupv	405	103	like	like	JJ
cord-256187-ofp7tupv	405	104	particles	particle	NNS
cord-256187-ofp7tupv	405	105	New	new	JJ
cord-256187-ofp7tupv	405	106	developments	development	NNS
cord-256187-ofp7tupv	405	107	in	in	IN
cord-256187-ofp7tupv	405	108	the	the	DT
cord-256187-ofp7tupv	405	109	induction	induction	NN
cord-256187-ofp7tupv	405	110	and	and	CC
cord-256187-ofp7tupv	405	111	antiviral	antiviral	JJ
cord-256187-ofp7tupv	405	112	effectors	effector	NNS
cord-256187-ofp7tupv	405	113	of	of	IN
cord-256187-ofp7tupv	405	114	type	type	NN
cord-256187-ofp7tupv	406	1	I	-PRON-	PRP
cord-256187-ofp7tupv	406	2	interferon	interferon	VBD
cord-256187-ofp7tupv	406	3	Ebola	Ebola	NNP
cord-256187-ofp7tupv	406	4	virus	virus	NN
cord-256187-ofp7tupv	406	5	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	406	6	counteracts	counteract	VBZ
cord-256187-ofp7tupv	406	7	BST-2	BST-2	NNP
cord-256187-ofp7tupv	406	8	/	/	SYM
cord-256187-ofp7tupv	406	9	Tetherin	tetherin	NN
cord-256187-ofp7tupv	406	10	restriction	restriction	NN
cord-256187-ofp7tupv	406	11	in	in	IN
cord-256187-ofp7tupv	406	12	a	a	DT
cord-256187-ofp7tupv	406	13	sequence	sequence	NN
cord-256187-ofp7tupv	406	14	-	-	HYPH
cord-256187-ofp7tupv	406	15	independent	independent	JJ
cord-256187-ofp7tupv	406	16	manner	manner	NN
cord-256187-ofp7tupv	406	17	that	that	WDT
cord-256187-ofp7tupv	406	18	does	do	VBZ
cord-256187-ofp7tupv	406	19	not	not	RB
cord-256187-ofp7tupv	406	20	require	require	VB
cord-256187-ofp7tupv	406	21	tetherin	tetherin	NNP
cord-256187-ofp7tupv	406	22	surface	surface	NN
cord-256187-ofp7tupv	406	23	removal	removal	NN
cord-256187-ofp7tupv	407	1	The	the	DT
cord-256187-ofp7tupv	407	2	IFITM	IFITM	NNP
cord-256187-ofp7tupv	407	3	proteins	protein	NNS
cord-256187-ofp7tupv	407	4	inhibit	inhibit	VBP
cord-256187-ofp7tupv	407	5	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	407	6	infection	infection	NN
cord-256187-ofp7tupv	407	7	Protection	Protection	NNP
cord-256187-ofp7tupv	407	8	from	from	IN
cord-256187-ofp7tupv	407	9	lethal	lethal	JJ
cord-256187-ofp7tupv	407	10	infection	infection	NN
cord-256187-ofp7tupv	407	11	is	be	VBZ
cord-256187-ofp7tupv	407	12	determined	determine	VBN
cord-256187-ofp7tupv	407	13	by	by	IN
cord-256187-ofp7tupv	407	14	innate	innate	JJ
cord-256187-ofp7tupv	407	15	immune	immune	JJ
cord-256187-ofp7tupv	407	16	responses	response	NNS
cord-256187-ofp7tupv	407	17	in	in	IN
cord-256187-ofp7tupv	407	18	a	a	DT
cord-256187-ofp7tupv	407	19	mouse	mouse	NN
cord-256187-ofp7tupv	407	20	model	model	NN
cord-256187-ofp7tupv	407	21	of	of	IN
cord-256187-ofp7tupv	407	22	Ebola	Ebola	NNP
cord-256187-ofp7tupv	407	23	virus	virus	NN
cord-256187-ofp7tupv	407	24	infection	infection	NN
cord-256187-ofp7tupv	407	25	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	407	26	Vpu	Vpu	NNP
cord-256187-ofp7tupv	407	27	neutralizes	neutralize	VBZ
cord-256187-ofp7tupv	407	28	the	the	DT
cord-256187-ofp7tupv	407	29	antiviral	antiviral	JJ
cord-256187-ofp7tupv	407	30	factor	factor	NN
cord-256187-ofp7tupv	407	31	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	407	32	/	/	SYM
cord-256187-ofp7tupv	407	33	BST-2	BST-2	NNP
cord-256187-ofp7tupv	407	34	by	by	IN
cord-256187-ofp7tupv	407	35	binding	bind	VBG
cord-256187-ofp7tupv	407	36	it	-PRON-	PRP
cord-256187-ofp7tupv	407	37	and	and	CC
cord-256187-ofp7tupv	407	38	directing	direct	VBG
cord-256187-ofp7tupv	407	39	its	-PRON-	PRP$
cord-256187-ofp7tupv	407	40	beta	beta	JJ
cord-256187-ofp7tupv	407	41	-	-	HYPH
cord-256187-ofp7tupv	407	42	TrCP2-dependent	trcp2-dependent	JJ
cord-256187-ofp7tupv	407	43	degradation	degradation	NN
cord-256187-ofp7tupv	407	44	Molecular	Molecular	NNP
cord-256187-ofp7tupv	407	45	mechanism	mechanism	NN
cord-256187-ofp7tupv	407	46	of	of	IN
cord-256187-ofp7tupv	407	47	BST2	BST2	NNP
cord-256187-ofp7tupv	407	48	/	/	SYM
cord-256187-ofp7tupv	407	49	tetherin	tetherin	XX
cord-256187-ofp7tupv	407	50	downregulation	downregulation	NN
cord-256187-ofp7tupv	407	51	by	by	IN
cord-256187-ofp7tupv	407	52	K5	K5	NNP
cord-256187-ofp7tupv	407	53	/	/	SYM
cord-256187-ofp7tupv	407	54	MIR2	MIR2	NNP
cord-256187-ofp7tupv	407	55	of	of	IN
cord-256187-ofp7tupv	407	56	Kaposi	Kaposi	NNP
cord-256187-ofp7tupv	407	57	's	's	POS
cord-256187-ofp7tupv	407	58	sarcoma	sarcoma	NN
cord-256187-ofp7tupv	407	59	-	-	HYPH
cord-256187-ofp7tupv	407	60	associated	associate	VBN
cord-256187-ofp7tupv	407	61	herpesvirus	herpesvirus	NN
cord-256187-ofp7tupv	407	62	Ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	407	63	VP24	VP24	NNP
cord-256187-ofp7tupv	408	1	binding	bind	VBG
cord-256187-ofp7tupv	408	2	to	to	IN
cord-256187-ofp7tupv	408	3	karyopherins	karyopherins	NNP
cord-256187-ofp7tupv	408	4	is	be	VBZ
cord-256187-ofp7tupv	408	5	required	require	VBN
cord-256187-ofp7tupv	408	6	for	for	IN
cord-256187-ofp7tupv	408	7	inhibition	inhibition	NN
cord-256187-ofp7tupv	408	8	of	of	IN
cord-256187-ofp7tupv	408	9	interferon	interferon	NN
cord-256187-ofp7tupv	408	10	signaling	signal	VBG
cord-256187-ofp7tupv	408	11	Species	species	NN
cord-256187-ofp7tupv	408	12	-	-	HYPH
cord-256187-ofp7tupv	408	13	specific	specific	JJ
cord-256187-ofp7tupv	408	14	activity	activity	NN
cord-256187-ofp7tupv	408	15	of	of	IN
cord-256187-ofp7tupv	408	16	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	408	17	Vpu	Vpu	NNP
cord-256187-ofp7tupv	408	18	and	and	CC
cord-256187-ofp7tupv	408	19	positive	positive	JJ
cord-256187-ofp7tupv	408	20	selection	selection	NN
cord-256187-ofp7tupv	408	21	of	of	IN
cord-256187-ofp7tupv	408	22	tetherin	tetherin	NNP
cord-256187-ofp7tupv	408	23	transmembrane	transmembrane	NNP
cord-256187-ofp7tupv	408	24	domain	domain	NN
cord-256187-ofp7tupv	409	1	variants	variant	NNS
cord-256187-ofp7tupv	410	1	A	a	DT
cord-256187-ofp7tupv	410	2	new	new	JJ
cord-256187-ofp7tupv	410	3	Ebola	Ebola	NNP
cord-256187-ofp7tupv	410	4	virus	virus	NN
cord-256187-ofp7tupv	410	5	nonstructural	nonstructural	JJ
cord-256187-ofp7tupv	410	6	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	410	7	expressed	express	VBN
cord-256187-ofp7tupv	410	8	through	through	IN
cord-256187-ofp7tupv	410	9	RNA	RNA	NNP
cord-256187-ofp7tupv	410	10	editing	editing	NN
cord-256187-ofp7tupv	410	11	Vpu	Vpu	NNP
cord-256187-ofp7tupv	410	12	antagonizes	antagonize	VBZ
cord-256187-ofp7tupv	410	13	BST-2-mediated	bst-2-mediate	VBN
cord-256187-ofp7tupv	410	14	restriction	restriction	NN
cord-256187-ofp7tupv	410	15	of	of	IN
cord-256187-ofp7tupv	410	16	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	410	17	release	release	VBP
cord-256187-ofp7tupv	410	18	via	via	IN
cord-256187-ofp7tupv	410	19	beta	beta	NN
cord-256187-ofp7tupv	410	20	-	-	HYPH
cord-256187-ofp7tupv	410	21	TrCP	trcp	NN
cord-256187-ofp7tupv	410	22	and	and	CC
cord-256187-ofp7tupv	410	23	endo	endo	NN
cord-256187-ofp7tupv	410	24	-	-	HYPH
cord-256187-ofp7tupv	410	25	lysosomal	lysosomal	JJ
cord-256187-ofp7tupv	410	26	trafficking	traffic	VBG
cord-256187-ofp7tupv	410	27	Comparison	comparison	NN
cord-256187-ofp7tupv	410	28	of	of	IN
cord-256187-ofp7tupv	410	29	the	the	DT
cord-256187-ofp7tupv	410	30	transcription	transcription	NN
cord-256187-ofp7tupv	410	31	and	and	CC
cord-256187-ofp7tupv	410	32	replication	replication	NN
cord-256187-ofp7tupv	410	33	strategies	strategy	NNS
cord-256187-ofp7tupv	410	34	of	of	IN
cord-256187-ofp7tupv	410	35	marburg	marburg	NNP
cord-256187-ofp7tupv	410	36	virus	virus	NN
cord-256187-ofp7tupv	410	37	and	and	CC
cord-256187-ofp7tupv	410	38	Ebola	Ebola	NNP
cord-256187-ofp7tupv	410	39	virus	virus	NN
cord-256187-ofp7tupv	410	40	by	by	IN
cord-256187-ofp7tupv	410	41	using	use	VBG
cord-256187-ofp7tupv	410	42	artificial	artificial	JJ
cord-256187-ofp7tupv	410	43	replication	replication	NN
cord-256187-ofp7tupv	410	44	systems	system	NNS
cord-256187-ofp7tupv	411	1	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	411	2	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	411	3	retrovirus	retrovirus	NN
cord-256187-ofp7tupv	411	4	release	release	NN
cord-256187-ofp7tupv	411	5	and	and	CC
cord-256187-ofp7tupv	411	6	is	be	VBZ
cord-256187-ofp7tupv	411	7	antagonized	antagonize	VBN
cord-256187-ofp7tupv	411	8	by	by	IN
cord-256187-ofp7tupv	411	9	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	411	10	Vpu	Vpu	NNP
cord-256187-ofp7tupv	411	11	Plasma	Plasma	NNP
cord-256187-ofp7tupv	411	12	membrane	membrane	NN
cord-256187-ofp7tupv	411	13	rafts	raft	NNS
cord-256187-ofp7tupv	411	14	play	play	VBP
cord-256187-ofp7tupv	411	15	a	a	DT
cord-256187-ofp7tupv	411	16	critical	critical	JJ
cord-256187-ofp7tupv	411	17	role	role	NN
cord-256187-ofp7tupv	411	18	in	in	IN
cord-256187-ofp7tupv	411	19	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	411	20	assembly	assembly	NN
cord-256187-ofp7tupv	411	21	and	and	CC
cord-256187-ofp7tupv	411	22	release	release	NN
cord-256187-ofp7tupv	412	1	The	the	DT
cord-256187-ofp7tupv	412	2	RING	ring	NN
cord-256187-ofp7tupv	412	3	-	-	HYPH
cord-256187-ofp7tupv	412	4	CH	ch	NN
cord-256187-ofp7tupv	412	5	ligase	ligase	NN
cord-256187-ofp7tupv	412	6	K5	K5	NNP
cord-256187-ofp7tupv	412	7	antagonizes	antagonize	VBZ
cord-256187-ofp7tupv	412	8	restriction	restriction	NN
cord-256187-ofp7tupv	412	9	of	of	IN
cord-256187-ofp7tupv	412	10	KSHV	KSHV	NNP
cord-256187-ofp7tupv	412	11	and	and	CC
cord-256187-ofp7tupv	412	12	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	412	13	particle	particle	NN
cord-256187-ofp7tupv	412	14	release	release	NN
cord-256187-ofp7tupv	412	15	by	by	IN
cord-256187-ofp7tupv	412	16	mediating	mediate	VBG
cord-256187-ofp7tupv	412	17	ubiquitindependent	ubiquitindependent	JJ
cord-256187-ofp7tupv	412	18	endosomal	endosomal	NNP
cord-256187-ofp7tupv	412	19	degradation	degradation	NN
cord-256187-ofp7tupv	412	20	of	of	IN
cord-256187-ofp7tupv	412	21	tetherin	tetherin	NNP
cord-256187-ofp7tupv	412	22	Tetherin	Tetherin	NNP
cord-256187-ofp7tupv	412	23	inhibits	inhibit	VBZ
cord-256187-ofp7tupv	412	24	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	412	25	release	release	NN
cord-256187-ofp7tupv	412	26	by	by	IN
cord-256187-ofp7tupv	412	27	directly	directly	RB
cord-256187-ofp7tupv	412	28	tethering	tether	VBG
cord-256187-ofp7tupv	412	29	virions	virion	NNS
cord-256187-ofp7tupv	412	30	to	to	TO
cord-256187-ofp7tupv	412	31	cells	cells	VB
cord-256187-ofp7tupv	412	32	Ebola	Ebola	NNP
cord-256187-ofp7tupv	412	33	virus	virus	NN
cord-256187-ofp7tupv	412	34	protein	protein	NN
cord-256187-ofp7tupv	412	35	VP35	VP35	NNP
cord-256187-ofp7tupv	412	36	impairs	impair	VBZ
cord-256187-ofp7tupv	412	37	the	the	DT
cord-256187-ofp7tupv	412	38	function	function	NN
cord-256187-ofp7tupv	412	39	of	of	IN
cord-256187-ofp7tupv	412	40	interferon	interferon	NN
cord-256187-ofp7tupv	412	41	regulatory	regulatory	JJ
cord-256187-ofp7tupv	412	42	factor	factor	NN
cord-256187-ofp7tupv	412	43	-	-	HYPH
cord-256187-ofp7tupv	412	44	activating	activate	VBG
cord-256187-ofp7tupv	412	45	kinases	kinase	NNS
cord-256187-ofp7tupv	412	46	IKKepsilon	IKKepsilon	NNP
cord-256187-ofp7tupv	412	47	and	and	CC
cord-256187-ofp7tupv	412	48	TBK-1	TBK-1	NNP
cord-256187-ofp7tupv	412	49	Basic	basic	JJ
cord-256187-ofp7tupv	412	50	residues	residue	NNS
cord-256187-ofp7tupv	412	51	within	within	IN
cord-256187-ofp7tupv	412	52	the	the	DT
cord-256187-ofp7tupv	412	53	ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	412	54	VP35	VP35	NNP
cord-256187-ofp7tupv	412	55	protein	protein	NN
cord-256187-ofp7tupv	412	56	are	be	VBP
cord-256187-ofp7tupv	412	57	required	require	VBN
cord-256187-ofp7tupv	412	58	for	for	IN
cord-256187-ofp7tupv	412	59	its	-PRON-	PRP$
cord-256187-ofp7tupv	412	60	viral	viral	JJ
cord-256187-ofp7tupv	412	61	polymerase	polymerase	NN
cord-256187-ofp7tupv	412	62	cofactor	cofactor	NN
cord-256187-ofp7tupv	412	63	function	function	NN
cord-256187-ofp7tupv	412	64	Mutations	mutation	NNS
cord-256187-ofp7tupv	412	65	abrogating	abrogate	VBG
cord-256187-ofp7tupv	412	66	VP35	VP35	NNP
cord-256187-ofp7tupv	412	67	interaction	interaction	NN
cord-256187-ofp7tupv	412	68	with	with	IN
cord-256187-ofp7tupv	412	69	double	double	RB
cord-256187-ofp7tupv	412	70	-	-	HYPH
cord-256187-ofp7tupv	412	71	stranded	strand	VBN
cord-256187-ofp7tupv	412	72	RNA	RNA	NNP
cord-256187-ofp7tupv	412	73	render	render	VB
cord-256187-ofp7tupv	412	74	Ebola	Ebola	NNP
cord-256187-ofp7tupv	412	75	virus	virus	NN
cord-256187-ofp7tupv	412	76	avirulent	avirulent	NN
cord-256187-ofp7tupv	412	77	in	in	IN
cord-256187-ofp7tupv	412	78	guinea	guinea	NN
cord-256187-ofp7tupv	412	79	pigs	pig	NNS
cord-256187-ofp7tupv	412	80	Infectious	Infectious	NNP
cord-256187-ofp7tupv	412	81	Lassa	Lassa	NNP
cord-256187-ofp7tupv	412	82	virus	virus	NN
cord-256187-ofp7tupv	412	83	,	,	,
cord-256187-ofp7tupv	412	84	but	but	CC
cord-256187-ofp7tupv	412	85	not	not	RB
cord-256187-ofp7tupv	412	86	filoviruses	filovirus	NNS
cord-256187-ofp7tupv	412	87	,	,	,
cord-256187-ofp7tupv	412	88	is	be	VBZ
cord-256187-ofp7tupv	412	89	restricted	restrict	VBN
cord-256187-ofp7tupv	412	90	by	by	IN
cord-256187-ofp7tupv	413	1	BST-2	BST-2	NNP
cord-256187-ofp7tupv	413	2	/	/	SYM
cord-256187-ofp7tupv	413	3	tetherin	tetherin	NNP
cord-256187-ofp7tupv	413	4	Homooligomerization	Homooligomerization	NNP
cord-256187-ofp7tupv	413	5	facilitates	facilitate	VBZ
cord-256187-ofp7tupv	413	6	the	the	DT
cord-256187-ofp7tupv	413	7	interferon	interferon	NN
cord-256187-ofp7tupv	413	8	-	-	HYPH
cord-256187-ofp7tupv	413	9	antagonist	antagonist	NN
cord-256187-ofp7tupv	413	10	activity	activity	NN
cord-256187-ofp7tupv	413	11	of	of	IN
cord-256187-ofp7tupv	413	12	the	the	DT
cord-256187-ofp7tupv	413	13	ebolavirus	ebolavirus	NN
cord-256187-ofp7tupv	413	14	VP35	VP35	NNP
cord-256187-ofp7tupv	413	15	protein	protein	NN
cord-256187-ofp7tupv	413	16	Ebola	Ebola	NNP
cord-256187-ofp7tupv	413	17	virus	virus	NN
cord-256187-ofp7tupv	413	18	VP24	VP24	NNP
cord-256187-ofp7tupv	413	19	binds	bind	VBZ
cord-256187-ofp7tupv	413	20	karyopherin	karyopherin	NNP
cord-256187-ofp7tupv	413	21	alpha1	alpha1	NN
cord-256187-ofp7tupv	413	22	and	and	CC
cord-256187-ofp7tupv	413	23	blocks	block	VBZ
cord-256187-ofp7tupv	413	24	STAT1	STAT1	NNP
cord-256187-ofp7tupv	413	25	nuclear	nuclear	JJ
cord-256187-ofp7tupv	413	26	accumulation	accumulation	NN
cord-256187-ofp7tupv	413	27	Ebola	Ebola	NNP
cord-256187-ofp7tupv	413	28	virus	virus	NN
cord-256187-ofp7tupv	414	1	VP24	VP24	NNP
cord-256187-ofp7tupv	414	2	proteins	protein	NNS
cord-256187-ofp7tupv	414	3	inhibit	inhibit	VBP
cord-256187-ofp7tupv	414	4	the	the	DT
cord-256187-ofp7tupv	414	5	interaction	interaction	NN
cord-256187-ofp7tupv	414	6	of	of	IN
cord-256187-ofp7tupv	414	7	NPI-1	NPI-1	NNP
cord-256187-ofp7tupv	414	8	subfamily	subfamily	NN
cord-256187-ofp7tupv	414	9	karyopherin	karyopherin	NNP
cord-256187-ofp7tupv	414	10	alpha	alpha	NN
cord-256187-ofp7tupv	414	11	proteins	protein	NNS
cord-256187-ofp7tupv	414	12	with	with	IN
cord-256187-ofp7tupv	414	13	activated	activate	VBN
cord-256187-ofp7tupv	414	14	STAT1	stat1	NN
cord-256187-ofp7tupv	415	1	Interferon	interferon	NN
cord-256187-ofp7tupv	415	2	-	-	HYPH
cord-256187-ofp7tupv	415	3	inducible	inducible	JJ
cord-256187-ofp7tupv	415	4	antiviral	antiviral	JJ
cord-256187-ofp7tupv	415	5	effectors	effector	NNS
cord-256187-ofp7tupv	415	6	Inhibition	Inhibition	NNP
cord-256187-ofp7tupv	415	7	of	of	IN
cord-256187-ofp7tupv	415	8	Lassa	Lassa	NNP
cord-256187-ofp7tupv	415	9	and	and	CC
cord-256187-ofp7tupv	415	10	Marburg	Marburg	NNP
cord-256187-ofp7tupv	415	11	virus	virus	NN
cord-256187-ofp7tupv	415	12	production	production	NN
cord-256187-ofp7tupv	415	13	by	by	IN
cord-256187-ofp7tupv	415	14	tetherin	tetherin	NNP
cord-256187-ofp7tupv	416	1	The	the	DT
cord-256187-ofp7tupv	416	2	virion	virion	NN
cord-256187-ofp7tupv	416	3	glycoproteins	glycoprotein	NNS
cord-256187-ofp7tupv	416	4	of	of	IN
cord-256187-ofp7tupv	416	5	Ebola	Ebola	NNP
cord-256187-ofp7tupv	416	6	viruses	virus	NNS
cord-256187-ofp7tupv	416	7	are	be	VBP
cord-256187-ofp7tupv	416	8	encoded	encode	VBN
cord-256187-ofp7tupv	416	9	in	in	IN
cord-256187-ofp7tupv	416	10	two	two	CD
cord-256187-ofp7tupv	416	11	reading	read	VBG
cord-256187-ofp7tupv	416	12	frames	frame	NNS
cord-256187-ofp7tupv	416	13	and	and	CC
cord-256187-ofp7tupv	416	14	are	be	VBP
cord-256187-ofp7tupv	416	15	expressed	express	VBN
cord-256187-ofp7tupv	416	16	through	through	IN
cord-256187-ofp7tupv	416	17	transcriptional	transcriptional	JJ
cord-256187-ofp7tupv	416	18	editing	editing	NN
cord-256187-ofp7tupv	416	19	Tetherin	tetherin	NN
cord-256187-ofp7tupv	416	20	-	-	HYPH
cord-256187-ofp7tupv	416	21	driven	drive	VBN
cord-256187-ofp7tupv	416	22	adaptation	adaptation	NN
cord-256187-ofp7tupv	416	23	of	of	IN
cord-256187-ofp7tupv	416	24	Vpu	Vpu	NNP
cord-256187-ofp7tupv	416	25	and	and	CC
cord-256187-ofp7tupv	416	26	Nef	Nef	NNP
cord-256187-ofp7tupv	416	27	function	function	NN
cord-256187-ofp7tupv	416	28	and	and	CC
cord-256187-ofp7tupv	416	29	the	the	DT
cord-256187-ofp7tupv	416	30	evolution	evolution	NN
cord-256187-ofp7tupv	416	31	of	of	IN
cord-256187-ofp7tupv	416	32	pandemic	pandemic	NN
cord-256187-ofp7tupv	416	33	and	and	CC
cord-256187-ofp7tupv	416	34	nonpandemic	nonpandemic	NNP
cord-256187-ofp7tupv	416	35	HIV-1	HIV-1	NNP
cord-256187-ofp7tupv	416	36	strains	strain	NNS
cord-256187-ofp7tupv	417	1	JAK	JAK	NNP
cord-256187-ofp7tupv	417	2	-	-	HYPH
cord-256187-ofp7tupv	417	3	STAT	STAT	NNP
cord-256187-ofp7tupv	417	4	signaling	signaling	NN
cord-256187-ofp7tupv	417	5	:	:	:
cord-256187-ofp7tupv	417	6	from	from	IN
cord-256187-ofp7tupv	417	7	interferons	interferon	NNS
cord-256187-ofp7tupv	417	8	to	to	IN
cord-256187-ofp7tupv	417	9	cytokines	cytokine	NNS
cord-256187-ofp7tupv	418	1	A	a	DT
cord-256187-ofp7tupv	418	2	diverse	diverse	JJ
cord-256187-ofp7tupv	418	3	range	range	NN
cord-256187-ofp7tupv	418	4	of	of	IN
cord-256187-ofp7tupv	418	5	gene	gene	NN
cord-256187-ofp7tupv	418	6	products	product	NNS
cord-256187-ofp7tupv	418	7	are	be	VBP
cord-256187-ofp7tupv	418	8	effectors	effector	NNS
cord-256187-ofp7tupv	418	9	of	of	IN
cord-256187-ofp7tupv	418	10	the	the	DT
cord-256187-ofp7tupv	418	11	type	type	NN
cord-256187-ofp7tupv	419	1	I	-PRON-	PRP
cord-256187-ofp7tupv	419	2	interferon	interferon	VBP
cord-256187-ofp7tupv	419	3	antiviral	antiviral	JJ
cord-256187-ofp7tupv	419	4	response	response	NN
cord-256187-ofp7tupv	420	1	Ebola	Ebola	NNP
cord-256187-ofp7tupv	420	2	virus	virus	NN
cord-256187-ofp7tupv	420	3	VP35	VP35	NNP
cord-256187-ofp7tupv	420	4	antagonizes	antagonize	VBZ
cord-256187-ofp7tupv	420	5	PKR	PKR	NNP
cord-256187-ofp7tupv	420	6	activity	activity	NN
cord-256187-ofp7tupv	420	7	through	through	IN
cord-256187-ofp7tupv	420	8	its	-PRON-	PRP$
cord-256187-ofp7tupv	420	9	C	c	NN
cord-256187-ofp7tupv	420	10	-	-	HYPH
cord-256187-ofp7tupv	420	11	terminal	terminal	NN
cord-256187-ofp7tupv	420	12	interferon	interferon	NN
cord-256187-ofp7tupv	420	13	inhibitory	inhibitory	JJ
cord-256187-ofp7tupv	420	14	domain	domain	NN
cord-256187-ofp7tupv	421	1	Extracellular	extracellular	JJ
cord-256187-ofp7tupv	421	2	signal	signal	NN
cord-256187-ofp7tupv	421	3	-	-	HYPH
cord-256187-ofp7tupv	421	4	dependent	dependent	JJ
cord-256187-ofp7tupv	421	5	nuclear	nuclear	JJ
cord-256187-ofp7tupv	421	6	import	import	NN
cord-256187-ofp7tupv	421	7	of	of	IN
cord-256187-ofp7tupv	421	8	Stat1	Stat1	NNS
cord-256187-ofp7tupv	421	9	is	be	VBZ
cord-256187-ofp7tupv	421	10	mediated	mediate	VBN
cord-256187-ofp7tupv	421	11	by	by	IN
cord-256187-ofp7tupv	421	12	nuclear	nuclear	JJ
cord-256187-ofp7tupv	421	13	pore	pore	NN
cord-256187-ofp7tupv	421	14	-	-	HYPH
cord-256187-ofp7tupv	421	15	targeting	target	VBG
cord-256187-ofp7tupv	421	16	complex	complex	JJ
cord-256187-ofp7tupv	421	17	formation	formation	NN
cord-256187-ofp7tupv	421	18	with	with	IN
cord-256187-ofp7tupv	421	19	NPI-1	NPI-1	NNP
cord-256187-ofp7tupv	421	20	,	,	,
cord-256187-ofp7tupv	421	21	but	but	CC
cord-256187-ofp7tupv	421	22	not	not	RB
cord-256187-ofp7tupv	421	23	Rch1	Rch1	NNP
cord-256187-ofp7tupv	422	1	The	the	DT
cord-256187-ofp7tupv	422	2	small	small	JJ
cord-256187-ofp7tupv	422	3	interferon	interferon	NN
cord-256187-ofp7tupv	422	4	-	-	HYPH
cord-256187-ofp7tupv	422	5	induced	induce	VBN
cord-256187-ofp7tupv	422	6	transmembrane	transmembrane	NN
cord-256187-ofp7tupv	422	7	genes	gene	NNS
cord-256187-ofp7tupv	422	8	and	and	CC
cord-256187-ofp7tupv	422	9	proteins	protein	NNS
cord-256187-ofp7tupv	422	10	Ebola	Ebola	NNP
cord-256187-ofp7tupv	422	11	Virus	Virus	NNP
cord-256187-ofp7tupv	422	12	Counters	counter	NNS
cord-256187-ofp7tupv	423	1	the	the	DT
cord-256187-ofp7tupv	423	2	Interferon	Interferon	NNP
cord-256187-ofp7tupv	423	3	System	System	NNP
cord-256187-ofp7tupv	423	4	A.	a.	NN
cord-256187-ofp7tupv	423	5	Kü	Kü	NNP
cord-256187-ofp7tupv	423	6	hl	hl	NNP
cord-256187-ofp7tupv	423	7	and	and	CC
cord-256187-ofp7tupv	424	1	S.	S.	NNP
cord-256187-ofp7tupv	424	2	Pö	Pö	NNP
cord-256187-ofp7tupv	424	3	hlmann	hlmann	NN
cord-256187-ofp7tupv	424	4	Inhibitors	Inhibitors	NNP
cord-256187-ofp7tupv	424	5	of	of	IN
cord-256187-ofp7tupv	424	6	cathepsin	cathepsin	NN
cord-256187-ofp7tupv	425	1	L	l	NN
cord-256187-ofp7tupv	425	2	prevent	prevent	VBP
cord-256187-ofp7tupv	425	3	severe	severe	JJ
cord-256187-ofp7tupv	425	4	acute	acute	JJ
cord-256187-ofp7tupv	425	5	respiratory	respiratory	JJ
cord-256187-ofp7tupv	425	6	syndrome	syndrome	NN
cord-256187-ofp7tupv	425	7	coronavirus	coronavirus	NN
cord-256187-ofp7tupv	425	8	entry	entry	NN
cord-256187-ofp7tupv	425	9	Experimental	experimental	JJ
cord-256187-ofp7tupv	425	10	inoculation	inoculation	NN
cord-256187-ofp7tupv	425	11	of	of	IN
cord-256187-ofp7tupv	425	12	plants	plant	NNS
cord-256187-ofp7tupv	425	13	and	and	CC
cord-256187-ofp7tupv	425	14	animals	animal	NNS
cord-256187-ofp7tupv	425	15	with	with	IN
cord-256187-ofp7tupv	425	16	Ebola	Ebola	NNP
cord-256187-ofp7tupv	425	17	virus	virus	NN
cord-256187-ofp7tupv	425	18	A	a	DT
cord-256187-ofp7tupv	425	19	system	system	NN
cord-256187-ofp7tupv	425	20	for	for	IN
cord-256187-ofp7tupv	425	21	functional	functional	JJ
cord-256187-ofp7tupv	425	22	analysis	analysis	NN
cord-256187-ofp7tupv	425	23	of	of	IN
cord-256187-ofp7tupv	425	24	Ebola	Ebola	NNP
cord-256187-ofp7tupv	425	25	virus	virus	NN
cord-256187-ofp7tupv	425	26	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	425	27	Newly	newly	RB
cord-256187-ofp7tupv	425	28	discovered	discover	VBN
cord-256187-ofp7tupv	425	29	Ebola	Ebola	NNP
cord-256187-ofp7tupv	425	30	virus	virus	NN
cord-256187-ofp7tupv	425	31	associated	associate	VBN
cord-256187-ofp7tupv	425	32	with	with	IN
cord-256187-ofp7tupv	425	33	hemorrhagic	hemorrhagic	JJ
cord-256187-ofp7tupv	425	34	fever	fever	NN
cord-256187-ofp7tupv	425	35	outbreak	outbreak	NN
cord-256187-ofp7tupv	425	36	in	in	IN
cord-256187-ofp7tupv	425	37	Uganda	Uganda	NNP
cord-256187-ofp7tupv	425	38	.	.	.
cord-256187-ofp7tupv	426	1	PLoS	PLoS	NNP
cord-256187-ofp7tupv	426	2	Pathog	Pathog	NNP
cord-256187-ofp7tupv	426	3	.	.	.
cord-256187-ofp7tupv	427	1	4	4	LS
cord-256187-ofp7tupv	427	2	,	,	,
cord-256187-ofp7tupv	427	3	e1000212	e1000212	NNP
cord-256187-ofp7tupv	427	4	GP	GP	NNP
cord-256187-ofp7tupv	427	5	mRNA	mrna	NN
cord-256187-ofp7tupv	427	6	of	of	IN
cord-256187-ofp7tupv	427	7	Ebola	Ebola	NNP
cord-256187-ofp7tupv	427	8	virus	virus	NN
cord-256187-ofp7tupv	427	9	is	be	VBZ
cord-256187-ofp7tupv	427	10	edited	edit	VBN
cord-256187-ofp7tupv	427	11	by	by	IN
cord-256187-ofp7tupv	427	12	the	the	DT
cord-256187-ofp7tupv	427	13	Ebola	Ebola	NNP
cord-256187-ofp7tupv	427	14	virus	virus	NN
cord-256187-ofp7tupv	427	15	polymerase	polymerase	NN
cord-256187-ofp7tupv	427	16	and	and	CC
cord-256187-ofp7tupv	427	17	by	by	IN
cord-256187-ofp7tupv	427	18	T7	T7	NNP
cord-256187-ofp7tupv	427	19	and	and	CC
cord-256187-ofp7tupv	427	20	vaccinia	vaccinia	NN
cord-256187-ofp7tupv	427	21	virus	virus	NN
cord-256187-ofp7tupv	427	22	polymerases	polymerases	VBP
cord-256187-ofp7tupv	427	23	Processing	process	VBG
cord-256187-ofp7tupv	427	24	of	of	IN
cord-256187-ofp7tupv	427	25	the	the	DT
cord-256187-ofp7tupv	427	26	Ebola	Ebola	NNP
cord-256187-ofp7tupv	427	27	virus	virus	NN
cord-256187-ofp7tupv	427	28	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	427	29	by	by	IN
cord-256187-ofp7tupv	427	30	the	the	DT
cord-256187-ofp7tupv	427	31	proprotein	proprotein	NNP
cord-256187-ofp7tupv	427	32	convertase	convertase	NNP
cord-256187-ofp7tupv	427	33	furin	furin	NNP
cord-256187-ofp7tupv	427	34	Delta	Delta	NNP
cord-256187-ofp7tupv	427	35	-	-	HYPH
cord-256187-ofp7tupv	427	36	peptide	peptide	NN
cord-256187-ofp7tupv	427	37	is	be	VBZ
cord-256187-ofp7tupv	427	38	the	the	DT
cord-256187-ofp7tupv	427	39	carboxy	carboxy	JJ
cord-256187-ofp7tupv	427	40	-	-	HYPH
cord-256187-ofp7tupv	427	41	terminal	terminal	NN
cord-256187-ofp7tupv	427	42	cleavage	cleavage	NN
cord-256187-ofp7tupv	427	43	fragment	fragment	NN
cord-256187-ofp7tupv	427	44	of	of	IN
cord-256187-ofp7tupv	427	45	the	the	DT
cord-256187-ofp7tupv	427	46	nonstructural	nonstructural	JJ
cord-256187-ofp7tupv	427	47	small	small	JJ
cord-256187-ofp7tupv	427	48	glycoprotein	glycoprotein	NN
cord-256187-ofp7tupv	427	49	sGP	sgp	XX
cord-256187-ofp7tupv	427	50	of	of	IN
cord-256187-ofp7tupv	427	51	Ebola	Ebola	NNP
cord-256187-ofp7tupv	427	52	virus	virus	NN
cord-256187-ofp7tupv	427	53	Effects	effect	NNS
cord-256187-ofp7tupv	427	54	of	of	IN
cord-256187-ofp7tupv	427	55	Ebola	Ebola	NNP
cord-256187-ofp7tupv	427	56	virus	virus	NN
cord-256187-ofp7tupv	427	57	glycoproteins	glycoprotein	VBZ
cord-256187-ofp7tupv	427	58	on	on	IN
cord-256187-ofp7tupv	427	59	endothelial	endothelial	JJ
cord-256187-ofp7tupv	427	60	cell	cell	NN
cord-256187-ofp7tupv	427	61	activation	activation	NN
cord-256187-ofp7tupv	427	62	and	and	CC
cord-256187-ofp7tupv	427	63	barrier	barrier	NN
cord-256187-ofp7tupv	427	64	function	function	NN
cord-256187-ofp7tupv	427	65	Influenza	Influenza	NNP
cord-256187-ofp7tupv	427	66	virus	virus	NN
cord-256187-ofp7tupv	427	67	is	be	VBZ
cord-256187-ofp7tupv	427	68	not	not	RB
cord-256187-ofp7tupv	427	69	restricted	restrict	VBN
cord-256187-ofp7tupv	427	70	by	by	IN
cord-256187-ofp7tupv	427	71	tetherin	tetherin	NNS
cord-256187-ofp7tupv	427	72	whereas	whereas	IN
cord-256187-ofp7tupv	427	73	influenza	influenza	NN
cord-256187-ofp7tupv	427	74	VLP	VLP	NNP
cord-256187-ofp7tupv	427	75	production	production	NN
cord-256187-ofp7tupv	427	76	is	be	VBZ
cord-256187-ofp7tupv	427	77	restricted	restrict	VBN
cord-256187-ofp7tupv	427	78	by	by	IN
cord-256187-ofp7tupv	427	79	tetherin	tetherin	NNP
cord-256187-ofp7tupv	427	80	Interferon	Interferon	NNP
cord-256187-ofp7tupv	427	81	-	-	HYPH
cord-256187-ofp7tupv	427	82	induced	induce	VBN
cord-256187-ofp7tupv	427	83	cell	cell	NN
cord-256187-ofp7tupv	427	84	membrane	membrane	NN
cord-256187-ofp7tupv	427	85	proteins	protein	NNS
cord-256187-ofp7tupv	427	86	,	,	,
cord-256187-ofp7tupv	427	87	IFITM3	IFITM3	''
cord-256187-ofp7tupv	427	88	and	and	CC
cord-256187-ofp7tupv	427	89	tetherin	tetherin	NNP
cord-256187-ofp7tupv	427	90	,	,	,
cord-256187-ofp7tupv	427	91	inhibit	inhibit	VBP
cord-256187-ofp7tupv	427	92	vesicular	vesicular	JJ
cord-256187-ofp7tupv	427	93	stomatitis	stomatitis	NN
cord-256187-ofp7tupv	427	94	virus	virus	NN
cord-256187-ofp7tupv	427	95	infection	infection	NN
cord-256187-ofp7tupv	427	96	via	via	IN
cord-256187-ofp7tupv	427	97	distinct	distinct	JJ
cord-256187-ofp7tupv	427	98	mechanisms	mechanism	NNS
cord-256187-ofp7tupv	427	99	Characterization	characterization	NN
cord-256187-ofp7tupv	427	100	of	of	IN
cord-256187-ofp7tupv	427	101	Ebola	Ebola	NNP
cord-256187-ofp7tupv	427	102	virus	virus	NN
cord-256187-ofp7tupv	427	103	entry	entry	NN
cord-256187-ofp7tupv	427	104	by	by	IN
cord-256187-ofp7tupv	427	105	using	use	VBG
cord-256187-ofp7tupv	427	106	pseudotyped	pseudotyped	NNS
cord-256187-ofp7tupv	427	107	viruses	virus	NNS
cord-256187-ofp7tupv	427	108	:	:	:
cord-256187-ofp7tupv	427	109	identification	identification	NN
cord-256187-ofp7tupv	427	110	of	of	IN
cord-256187-ofp7tupv	427	111	receptor	receptor	NN
cord-256187-ofp7tupv	427	112	-	-	HYPH
cord-256187-ofp7tupv	427	113	deficient	deficient	JJ
cord-256187-ofp7tupv	427	114	cell	cell	NN
cord-256187-ofp7tupv	427	115	lines	line	NNS
cord-256187-ofp7tupv	428	1	Budding	bud	VBG
cord-256187-ofp7tupv	428	2	capability	capability	NN
cord-256187-ofp7tupv	428	3	of	of	IN
cord-256187-ofp7tupv	428	4	the	the	DT
cord-256187-ofp7tupv	428	5	influenza	influenza	NN
cord-256187-ofp7tupv	428	6	virus	virus	NN
cord-256187-ofp7tupv	428	7	neuraminidase	neuraminidase	NN
cord-256187-ofp7tupv	428	8	can	can	MD
cord-256187-ofp7tupv	428	9	be	be	VB
cord-256187-ofp7tupv	428	10	modulated	modulate	VBN
cord-256187-ofp7tupv	428	11	by	by	IN
cord-256187-ofp7tupv	428	12	tetherin	tetherin	NNP
cord-256187-ofp7tupv	428	13	Palmitoylome	Palmitoylome	NNP
cord-256187-ofp7tupv	428	14	profiling	profiling	NN
cord-256187-ofp7tupv	428	15	reveals	reveal	VBZ
cord-256187-ofp7tupv	428	16	S	s	NN
cord-256187-ofp7tupv	428	17	-	-	HYPH
cord-256187-ofp7tupv	428	18	palmitoylation	palmitoylation	NN
cord-256187-ofp7tupv	428	19	-	-	HYPH
cord-256187-ofp7tupv	428	20	dependent	dependent	JJ
cord-256187-ofp7tupv	428	21	antiviral	antiviral	JJ
cord-256187-ofp7tupv	428	22	activity	activity	NN
cord-256187-ofp7tupv	428	23	of	of	IN
cord-256187-ofp7tupv	428	24	IFITM3	IFITM3	NNP
cord-256187-ofp7tupv	429	1	We	-PRON-	PRP
cord-256187-ofp7tupv	429	2	thank	thank	VBP
cord-256187-ofp7tupv	429	3	T.F.	T.F.	NNP
cord-256187-ofp7tupv	429	4	Schulz	Schulz	NNP
cord-256187-ofp7tupv	429	5	for	for	IN
cord-256187-ofp7tupv	429	6	support	support	NN
cord-256187-ofp7tupv	429	7	.	.	.