id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-004226-3ki0dzwb	Patel, Sunil	Inflammatory and microbiological associations with near-fatal asthma requiring extracorporeal membrane oxygenation	2020-01-27		.txt	text/plain	947	49	39	Patients with near-fatal asthma requiring ECMO are more likely to be younger and female and are also likely to have positive viral and fungal isolates on bronchoalveolar lavage when compared to those receiving conventional mechanical ventilation http://bit.ly/2S38SaC In this retrospective review of adult asthmatics admitted to intensive care for a near-fatal acute exacerbation, we report that the requirement for ECMO was associated with younger age, female sex and the presence of either fungal or rhinoviral infection in the lower airway. Studies have shown that virally mediated inflammatory pathways (acute or quiescent) are implicated in near-fatal asthma and occur in as much as 50% of patients [3] . To date, this is the first case series investigating inflammatory and microbial factors associated with the need for ECMO in near-fatal asthma and highlights rhinovirus infection as well as positive fungal isolates as being particularly associated with the need for ECMO.	./cache/cord-004226-3ki0dzwb.txt	./txt/cord-004226-3ki0dzwb.txt