id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-006621-0fxpn7qf	Cantwell, Tamara	Leptospirosis-associated catastrophic respiratory failure supported by extracorporeal membrane oxygenation	2017-10-10		.txt	text/plain	2503	159	38	title: Leptospirosis-associated catastrophic respiratory failure supported by extracorporeal membrane oxygenation The clinical relevance of the case is the scared evidence of leptospirosis-associated severe respiratory failure treated with ECMO. A high index of suspicion is needed for an adequate diagnosis of leptospirosis to implement the correct treatment, particularly in the association of respiratory failure, pulmonary hemorrhage, and an epidemiological-related context. Leptospirosis can present with a wide range of symptoms, mimicking flu, hepatitis, dengue, hanta virus cardiopulmonary syndrome, meningitis, among others, and has a specific treatment; thus, clinical suspicion must remain high and serological diagnosis should be performed. The most severe clinical form of leptospirosis is known as Weil's disease, which is uncommon (5-10% of cases), and is characterized by hepatic, renal, and pulmonary involvement [7] [8] [9] [10] [11] . In the case presented, profound septic shock, with MOF and catastrophic ARDS, made it impossible to ventilate the patient protectively and simultaneously supply adequate oxygenation and ventilation; thus, ECMO was initiated.	./cache/cord-006621-0fxpn7qf.txt	./txt/cord-006621-0fxpn7qf.txt