id author title date pages extension mime words sentences flesch summary cache txt cord-034303-kcu9guxa Laimoud, Mohamed The clinical significance of blood lactate levels in evaluation of adult patients with veno-arterial extracorporeal membrane oxygenation 2020-10-27 .txt text/plain 3194 170 44 The objective of this study was to detect the validity of serial measurements of arterial lactate level in differentiating hospital mortality and neurological outcome after VA-ECMO support for adult patients with cardiogenic shock. The non-survivors and the patients with acute cerebral strokes had significantly higher arterial lactate levels at pre-ECMO initiation, post-ECMO peak and after 24 h of ECMO support compared to the survivors and those without strokes, respectively. CONCLUSION: Progressive hyperlactatemia after VA-ECMO initiation for adult patients with cardiogenic shock is a sensitive and specific predictor of hospital mortality and acute cerebrovascular strokes. The objective of this study was to detect the validity of serial measurements of arterial lactate level in differentiating in-hospital mortality and neurological outcome after VA-ECMO support for patients with cardiogenic shock. Finally, our study revealed that the hospital mortality and neurological outcome of VA-ECMO were significantly associated with the severity of pre-ECMO shock state and the appropriate recovery of organs perfusion after ECMO support as indicated with changes of blood lactate levels. ./cache/cord-034303-kcu9guxa.txt ./txt/cord-034303-kcu9guxa.txt