id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-312748-9v2bmbod	Guo, Zhen	Anticoagulation Management in Severe COVID-19 Patients on Extracorporeal Membrane Oxygenation	2020-09-04		.txt	text/plain	3126	165	38	OBJECTIVE: To explore special coagulation characteristics and anticoagulation management in extracorporeal membrane oxygenation assisted patients with coronavirus disease 2019. CONCLUSIONS: Hypercoagulability and secondary hyperfibrinolysis during ECMO support in COVID-19 patients are common and possibly increase the propensity for thrombotic events and failure of the oxygenator. A majority of coronavirus disease 2019 (COVID-19) patients have mild symptoms and recover completely; however, approximately 5-14% become severely or critically ill with acute respiratory distress syndrome (ARDS) requiring intensive care unit (ICU) admission 3 . This study aims to summarize the coagulation characteristics, anticoagulation management, and complications of COVID-19 patients who received ECMO support in Shanghai, China. In this study we found that the clinical characteristics of COVID-19 patients were different from those of other viral pneumonia patients in terms of ECMO anticoagulation management and coagulation-related complications. In summary, hypercoagulability and secondary hyperfibrinolysis during ECMO support in COVID-19 patients were common and possibly increased the propensity for thrombotic events and oxygenator membrane failure.	./cache/cord-312748-9v2bmbod.txt	./txt/cord-312748-9v2bmbod.txt