id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-320031-e328fesl	Loforte, Antonio	Veno-venous Extracorporeal Membrane Oxygenation Support in COVID-19 Respiratory Distress Syndrome: Initial Experience	2020-06-01		.txt	text/plain	1672	119	52	By considering overall impact of COVID-19 pandemic outbreak, an increased need of extracorporeal membrane oxygenation (ECMO) support becomes evident. Consideration of ECMO was based on the presence of severe respiratory failure (Murray score >3.0 or pH <7.20 under protective ventilation 2,6-8 ) with sustained clinical deterioration despite optimal conventional treatment and refractory prone positioning. Aggressive mechanical ventilation (peak or plateau airway pressure >30 cm H2O or fraction of inspired oxygen [FIO2] >0.8) for more than 7 days, uncontrolled active bleeding, severe comorbidity, multiple organ failure, sepsis, disseminated intravascular coagulation, age >65 years, and neurologic damage were used as contraindications for VV ECMO institution. 2, [6] [7] [8] Regarding oxygenation, ECMO blood flow was maximized to reduce the FIO2 less than 0.6 and maintain hemoglobin Veno-venous Extracorporeal Membrane Oxygenation Support in COVID-19 Respiratory Distress Syndrome: Initial Experience saturation more than 85%.	./cache/cord-320031-e328fesl.txt	./txt/cord-320031-e328fesl.txt