id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-321149-hffj7s4o	Schmidt, Matthieu	Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study	2020-08-13		.txt	text/plain	5362	284	48	Methods This retrospective cohort study was done in the Paris–Sorbonne University Hospital Network, comprising five intensive care units (ICUs) and included patients who received ECMO for COVID-19 associated ARDS. This retrospective study, with 83 patients included and a complete follow-up until day 60 post-ECMO initiation is, to our knowledge, the largest to date reporting the outcomes after rescue ECMO for the most severe forms of COVID-19 ARDS, in the Paris-Sorbonne University Hospital Network (Paris, France), the principal hospital referral network for ICU care in Greater Paris, including one of the largest European ECMO centres (Pitié-Salpêtrière Hospital). Following early reports of severe COVID-19 associated coagulopathy [16] [17] [18] and frequent thromboembolic events on ECMO, inclu ding massive pulmonary embolism, 19, 20 we decided to increase the targeted activated partial thromboplastin time for anticoagulation of venovenous ECMO with unfractionated heparin to 60-75 s or anti-Xa activity 0·3-0·5 IU/mL (respective values were 40-55 s or 0·2-0·3 IU/mL in the EOLIA trial 3 ) before we treated our first patients with COVID-19 ARDS.	./cache/cord-321149-hffj7s4o.txt	./txt/cord-321149-hffj7s4o.txt