id author title date pages extension mime words sentences flesch summary cache txt cord-344326-025ioy3r Usman, AA A Case Series of Devastating Intracranial Hemorrhage during Venovenous Extracorporeal Membrane Oxygenation for COVID-19 2020-07-28 .txt text/plain 2991 189 44 This report was created to describe the authors' single institutional experience, with emphasis on the high rate of intracranial hemorrhage for the first 10 patients with COVID-19 placed on venovenous extracorporeal membrane oxygenation (VV ECMO). Despite maximal medical therapy, COVID-19 can progress to severe, refractory acute respiratory distress syndrome (ARDS) prompting clinicians to consider utilization of extracorporeal membrane oxygenation (ECMO) in appropriate cases, although early reports appeared to have high rates of mortality. This case series describes our single institutional neurological outcomes for the first ten patients placed on VV ECMO for COVID-19, of whom three had severe intraparenchymal hemorrhagic strokes resulting in death, one patient had a small subarachnoid hemorrhage and one patient had severe gastrointestinal bleeding. This unprecedented intracranial hemorrhage rate in COVID related ARDS requiring VV ECMO has prompted an evaluation of our anticoagulation practice by experts in hematology and neurology. ./cache/cord-344326-025ioy3r.txt ./txt/cord-344326-025ioy3r.txt